-- dump date 20140620_075304 -- class Genbank::misc_feature -- table misc_feature_note -- id note 663951000001 chromosomal replication initiation protein; Reviewed; Region: dnaA; PRK00149 663951000002 DnaA N-terminal domain; Region: DnaA_N; pfam11638 663951000003 The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009 663951000004 Walker A motif; other site 663951000005 ATP binding site [chemical binding]; other site 663951000006 The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cl17189 663951000007 Walker B motif; other site 663951000008 arginine finger; other site 663951000009 C-terminal domain of bacterial DnaA proteins. The DNA-binding C-terminal domain of DnaA contains a helix-turn-helix motif that specifically interacts with the DnaA box, a 9-mer motif that occurs repetitively in the replication origin oriC. Multiple...; Region: Bac_DnaA_C; cd06571 663951000010 DnaA box-binding interface [nucleotide binding]; other site 663951000011 HMMPfam hit to PF00308, Bac_DnaA, score 5.7e-144 663951000012 PS00017 ATP/GTP-binding site motif A (P-loop). 663951000013 HMMPfam hit to PF08299, Bac_DnaA_C, score 1.9e-42 663951000014 PS01008 DnaA protein signature. 663951000015 DNA polymerase III subunit beta; Validated; Region: PRK05643 663951000016 Beta clamp domain. The beta subunit (processivity factor) of DNA polymerase III holoenzyme, refered to as the beta clamp, forms a ring shaped dimer that encircles dsDNA (sliding clamp) in bacteria. The beta-clamp is structurally similar to the trimeric...; Region: beta_clamp; cd00140 663951000017 putative DNA binding surface [nucleotide binding]; other site 663951000018 dimer interface [polypeptide binding]; other site 663951000019 beta-clamp/clamp loader binding surface; other site 663951000020 beta-clamp/translesion DNA polymerase binding surface; other site 663951000021 HMMPfam hit to PF00712, DNA_pol3_beta, score 1.5e-66 663951000022 HMMPfam hit to PF02767, DNA_pol3_beta_2, score 4.3e-68 663951000023 HMMPfam hit to PF02768, DNA_pol3_beta_3, score 5.8e-60 663951000024 S4 domain protein YaaA; Region: YaaA_near_RecF; TIGR02988 663951000025 recF protein; Region: recf; TIGR00611 663951000026 ATP-binding cassette domain of RecF; Region: ABC_RecF; cd03242 663951000027 Walker A/P-loop; other site 663951000028 ATP binding site [chemical binding]; other site 663951000029 Q-loop/lid; other site 663951000030 ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201 663951000031 ABC transporter signature motif; other site 663951000032 Walker B; other site 663951000033 D-loop; other site 663951000034 H-loop/switch region; other site 663951000035 HMMPfam hit to PF02463, SMC_N, score 2.6e-08 663951000036 PS00017 ATP/GTP-binding site motif A (P-loop). 663951000037 PS00617 RecF protein signature 1. 663951000038 PS00618 RecF protein signature 2. 663951000039 DNA gyrase subunit B; Validated; Region: gyrB; PRK05644 663951000040 Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075 663951000041 Mg2+ binding site [ion binding]; other site 663951000042 G-X-G motif; other site 663951000043 TopoIIA_Trans_DNA_gyrase: Transducer domain, having a ribosomal S5 domain 2-like fold, of the type found in proteins of the type IIA family of DNA topoisomerases similar to the B subunits of E. coli DNA gyrase and E. coli Topoisomerase IV which are; Region: TopoII_Trans_DNA_gyrase; cd00822 663951000044 anchoring element; other site 663951000045 dimer interface [polypeptide binding]; other site 663951000046 ATP binding site [chemical binding]; other site 663951000047 TOPRIM_TopoIIA_GyrB: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in proteins of the type IIA family of DNA topoisomerases similar to the Escherichia coli GyrB subunit. TopoIIA enzymes cut both strands of the...; Region: TOPRIM_TopoIIA_GyrB; cd03366 663951000048 active site 663951000049 putative metal-binding site [ion binding]; other site 663951000050 DNA gyrase B subunit, carboxyl terminus; Region: DNA_gyraseB_C; pfam00986 663951000051 HMMPfam hit to PF02518, HATPase_c, score 1.7e-28 663951000052 PS00154 E1-E2 ATPases phosphorylation site. 663951000053 HMMPfam hit to PF00204, DNA_gyraseB, score 1.1e-94 663951000054 PS00177 DNA topoisomerase II signature. 663951000055 HMMPfam hit to PF01751, Toprim, score 1e-09 663951000056 HMMPfam hit to PF00986, DNA_gyraseB_C, score 1.5e-42 663951000057 DNA gyrase subunit A; Validated; Region: PRK05560 663951000058 DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes...; Region: TOP4c; cd00187 663951000059 CAP-like domain; other site 663951000060 active site 663951000061 primary dimer interface [polypeptide binding]; other site 663951000062 DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989 663951000063 DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989 663951000064 DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989 663951000065 DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989 663951000066 DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989 663951000067 DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989 663951000068 HMMPfam hit to PF00521, DNA_topoisoIV, score 0 663951000069 PS00017 ATP/GTP-binding site motif A (P-loop). 663951000070 HMMPfam hit to PF03989, DNA_gyraseA_C, score 2.9e-14 663951000071 HMMPfam hit to PF03989, DNA_gyraseA_C, score 5.4e-15 663951000072 HMMPfam hit to PF03989, DNA_gyraseA_C, score 2.2e-13 663951000073 HMMPfam hit to PF03989, DNA_gyraseA_C, score 6.2e-14 663951000074 HMMPfam hit to PF03989, DNA_gyraseA_C, score 7.6e-14 663951000075 HMMPfam hit to PF03989, DNA_gyraseA_C, score 2.6e-15 663951000076 B.subtilis YXKO protein of unknown function and related proteins. Based on the conservation of the ATP binding site, the substrate binding site and the Mg2+binding site and structural homology this group is a member of the ribokinase-like superfamily; Region: YXKO-related; cd01171 663951000077 putative substrate binding site [chemical binding]; other site 663951000078 putative ATP binding site [chemical binding]; other site 663951000079 HMMPfam hit to PF01256, Carb_kinase, score 1.1e-67 663951000080 PS01050 Uncharacterized protein family UPF0031 signature 2. 663951000081 PS01049 Uncharacterized protein family UPF0031 signature 1. 663951000082 1 probable transmembrane helix predicted for SATW20_00070 by TMHMM2.0 at aa 21-43 663951000083 Phenylalanine ammonia-lyase (PAL) and histidine ammonia-lyase (HAL); Region: PAL-HAL; cd00332 663951000084 active sites [active] 663951000085 tetramer interface [polypeptide binding]; other site 663951000086 HMMPfam hit to PF00221, PAL, score 6.2e-216 663951000087 PS00488 Phenylalanine and histidine ammonia-lyases signature. 663951000088 seryl-tRNA synthetase; Provisional; Region: PRK05431 663951000089 Seryl-tRNA synthetase N-terminal domain; Region: Seryl_tRNA_N; pfam02403 663951000090 Seryl-tRNA synthetase (SerRS) class II core catalytic domain. SerRS is responsible for the attachment of serine to the 3' OH group of ribose of the appropriate tRNA. This domain It is primarily responsible for ATP-dependent formation of the enzyme...; Region: SerRS_core; cd00770 663951000091 dimer interface [polypeptide binding]; other site 663951000092 active site 663951000093 motif 1; other site 663951000094 motif 2; other site 663951000095 motif 3; other site 663951000096 HMMPfam hit to PF02403, Seryl_tRNA_N, score 2.1e-46 663951000097 HMMPfam hit to PF00587, tRNA-synt_2b, score 9.7e-71 663951000098 PS00179 Aminoacyl-transfer RNA synthetases class-II signature 1. 663951000099 Predicted branched-chain amino acid permease (azaleucine resistance) [Amino acid transport and metabolism]; Region: AzlC; COG1296 663951000100 7 probable transmembrane helices predicted for SATW20_00100 by TMHMM2.0 at aa 15-32, 37-59, 63-85,134-156, 161-183, 190-208 and 212-229 663951000101 HMMPfam hit to PF03591, AzlC, score 1.4e-65 663951000102 Predicted membrane protein [Function unknown]; Region: COG4392 663951000103 4 probable transmembrane helices predicted for SATW20_00110 by TMHMM2.0 at aa 7-29, 39-58, 70-87 and 91-108 663951000104 HMMPfam hit to PF05437, AzlD, score 7.7e-36 663951000105 Homoserine acetyltransferase [Amino acid transport and metabolism]; Region: MET2; COG2021 663951000106 homoserine O-acetyltransferase; Provisional; Region: metX; cl17114 663951000107 HMMPfam hit to PF00561, Abhydrolase_1, score 5.8e-08 663951000108 Predicted membrane protein [Function unknown]; Region: COG4241 663951000109 7 probable transmembrane helices predicted for SATW20_00130 by TMHMM2.0 at aa 21-43, 53-86, 99-121,167-189, 202-224, 234-256 and 269-291 663951000110 Predicted signaling protein consisting of a modified GGDEF domain and a DHH domain [Signal transduction mechanisms]; Region: COG3887 663951000111 Class III nucleotidyl cyclases; Region: Nucleotidyl_cyc_III; cl11967 663951000112 DHH family; Region: DHH; pfam01368 663951000113 DHHA1 domain; Region: DHHA1; pfam02272 663951000114 2 probable transmembrane helices predicted for SATW20_00140 by TMHMM2.0 at aa 9-31 and 35-54 663951000115 HMMPfam hit to PF01368, DHH, score 2.7e-44 663951000116 HMMPfam hit to PF02272, DHHA1, score 3e-09 663951000117 50S ribosomal protein L9; Reviewed; Region: rplI; PRK00137 663951000118 Ribosomal protein L9, N-terminal domain; Region: Ribosomal_L9_N; pfam01281 663951000119 Ribosomal protein L9, C-terminal domain; Region: Ribosomal_L9_C; pfam03948 663951000120 HMMPfam hit to PF01281, Ribosomal_L9_N, score 8.7e-23 663951000121 PS00651 Ribosomal protein L9 signature. 663951000122 HMMPfam hit to PF03948, Ribosomal_L9_C, score 9.8e-32 663951000123 replicative DNA helicase; Region: DnaB; TIGR00665 663951000124 DnaB-like helicase N terminal domain; Region: DnaB; pfam00772 663951000125 DnaB helicase C terminal domain. The hexameric helicase DnaB unwinds the DNA duplex at the chromosome replication fork. Although the mechanism by which DnaB both couples ATP hydrolysis to translocation along DNA and denatures the duplex is unknown, a...; Region: DnaB_C; cd00984 663951000126 Walker A motif; other site 663951000127 ATP binding site [chemical binding]; other site 663951000128 Walker B motif; other site 663951000129 DNA binding loops [nucleotide binding] 663951000130 HMMPfam hit to PF00772, DnaB, score 2e-49 663951000131 HMMPfam hit to PF03796, DnaB_C, score 1.5e-142 663951000132 PS00017 ATP/GTP-binding site motif A (P-loop). 663951000133 Predicted helix-turn-helix motif with score 1117.000, SD 2.99 at aa 346-367, sequence RTLKALARELECPVIALSQLSR 663951000134 Adenylosuccinate synthetase; Region: Adenylsucc_synt; smart00788 663951000135 Adenylosuccinate synthetase (AdSS) catalyzes the first step in the de novo biosynthesis of AMP. IMP and L-aspartate are conjugated in a two-step reaction accompanied by the hydrolysis of GTP to GDP in the presence of Mg2+. In the first step, the...; Region: AdSS; cd03108 663951000136 GDP-binding site [chemical binding]; other site 663951000137 ACT binding site; other site 663951000138 IMP binding site; other site 663951000139 HMMPfam hit to PF00709, Adenylsucc_synt, score 5.4e-285 663951000140 PS01266 Adenylosuccinate synthetase GTP-binding site. 663951000141 PS00513 Adenylosuccinate synthetase active site. 663951000142 PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 663951000143 Predicted helix-turn-helix motif with score 1007.000, SD 2.62 at aa 287-308, sequence HHIREVGREYGTTTGRPRRVGW 663951000144 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745 663951000145 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 663951000146 active site 663951000147 phosphorylation site [posttranslational modification] 663951000148 intermolecular recognition site; other site 663951000149 dimerization interface [polypeptide binding]; other site 663951000150 Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383 663951000151 DNA binding site [nucleotide binding] 663951000152 HMMPfam hit to PF00072, Response_reg, score 4.1e-39 663951000153 HMMPfam hit to PF00486, Trans_reg_C, score 1.5e-23 663951000154 Signal transduction histidine kinase [Signal transduction mechanisms]; Region: VicK; COG5002 663951000155 Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225 663951000156 dimerization interface [polypeptide binding]; other site 663951000157 PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130 663951000158 putative active site [active] 663951000159 heme pocket [chemical binding]; other site 663951000160 Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082 663951000161 dimer interface [polypeptide binding]; other site 663951000162 phosphorylation site [posttranslational modification] 663951000163 Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075 663951000164 ATP binding site [chemical binding]; other site 663951000165 Mg2+ binding site [ion binding]; other site 663951000166 G-X-G motif; other site 663951000167 2 probable transmembrane helices predicted for SATW20_00190 by TMHMM2.0 at aa 15-37 and 183-205 663951000168 HMMPfam hit to PF00672, HAMP, score 1.8e-21 663951000169 HMMPfam hit to PF00989, PAS, score 1.3e-10 663951000170 HMMPfam hit to PF00512, HisKA, score 3.2e-24 663951000171 HMMPfam hit to PF02518, HATPase_c, score 6.1e-43 663951000172 Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4863 663951000173 YycH protein; Region: YycH; pfam07435 663951000174 HMMPfam hit to PF07435, YycH, score 1.8e-242 663951000175 1 probable transmembrane helix predicted for SATW20_00200 by TMHMM2.0 at aa 7-29 663951000176 YycH protein; Region: YycI; cl02015 663951000177 1 probable transmembrane helix predicted for SATW20_00210 by TMHMM2.0 at aa 9-26 663951000178 Metal-dependent hydrolases of the beta-lactamase superfamily I [General function prediction only]; Region: PhnP; COG1235 663951000179 HMMPfam hit to PF00753, Lactamase_B, score 2.6e-19 663951000180 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases [Nucleotide transport and metabolism]; Region: UshA; COG0737 663951000181 Staphylococcus aureus SA0022 and related proteins, N-terminal metallophosphatase domain; Region: MPP_SA0022_N; cd07408 663951000182 putative active site [active] 663951000183 putative metal binding site [ion binding]; other site 663951000184 5'-nucleotidase, C-terminal domain; Region: 5_nucleotid_C; pfam02872 663951000185 LPXTG-motif cell wall anchor domain; Region: LPXTG_anchor; TIGR01167 663951000186 HMMPfam hit to PF00149, Metallophos, score 4e-17 663951000187 PS00786 5'-nucleotidase signature 2. 663951000188 HMMPfam hit to PF02872, 5_nucleotid_C, score 2.7e-63 663951000189 HMMPfam hit to PF00746, Gram_pos_anchor, score 0.0001 663951000190 PS00343 Gram-positive cocci surface proteins 'anchoring' hexapeptide. 663951000191 rRNA large subunit methyltransferase; Provisional; Region: PRK00103 663951000192 HMMPfam hit to PF02590, DUF163, score 8.2e-137 663951000193 SCCmercury 663951000194 Predicted restriction endonuclease [Defense mechanisms]; Region: COG3183 663951000195 GIY-YIG domain of uncharacterized proteins from bacteria and their eukaryotic homologs; Region: GIY-YIG_COG3680; cd10440 663951000196 GIY-YIG motif/motif A; other site 663951000197 putative active site [active] 663951000198 putative metal binding site [ion binding]; other site 663951000199 CDS contains a frameshift after codon 224. Frameshift occurs at a poly A nonamer 663951000200 Family A polymerase primarily fills DNA gaps that arise during DNA repair, recombination and replication; Region: DNA_pol_A; cl02626 663951000201 active site 663951000202 DNA binding site [nucleotide binding] 663951000203 catalytic site [active] 663951000204 Phage associated DNA primase [General function prediction only]; Region: COG3378 663951000205 PS00017 ATP/GTP-binding site motif A (P-loop). 663951000206 CDS is disrupted by the insertion of an IS200-family element after codon 532 663951000207 HMMPfam hit to PF00239, Resolvase, score 2.3e-39 663951000208 HMMPfam hit to PF07508, Recombinase, score 1.2e-32 663951000209 HMMPfam hit to PF04606, Ogr_Delta, score 2.9e-16 663951000210 Transposase IS200 like; Region: Y1_Tnp; pfam01797 663951000211 HMMPfam hit to PF01797, Transposase_17, score 8.4e-59 663951000212 Staphylococcus protein of unknown function (DUF950); Region: DUF950; pfam06106 663951000213 HMMPfam hit to PF06106, DUF950, score 3.2e-93 663951000214 Staphylococcal protein of unknown function (DUF960); Region: DUF960; pfam06124 663951000215 HMMPfam hit to PF06124, DUF960, score 1.1e-71 663951000216 Protein of unknown function (DUF1643); Region: DUF1643; cl01787 663951000217 HMMPfam hit to PF07799, DUF1643, score 6.3e-73 663951000218 CDS contains a nonsense mutation (ochre) after codon 60 663951000219 Tn554 663951000220 Phage integrase, N-terminal SAM-like domain; Region: Phage_integr_N; cl12235 663951000221 tyrosine recombinase XerD; Region: recomb_XerD; TIGR02225 663951000222 Tn544A and related transposases, DNA breaking-rejoining enzymes, integrase/recombinases, C-terminal catalytic domain. This CD includes various bacterial transposases similar to TnpA from transposon Tn554; Region: INT_Tn554A_C; cd01194 663951000223 Int/Topo IB signature motif; other site 663951000224 HMMPfam hit to PF02899, Phage_integr_N, score 4.6e-05 663951000225 HMMPfam hit to PF00589, Phage_integrase, score 6.1e-55 663951000226 tyrosine recombinase XerC; Region: recomb_XerC; TIGR02224 663951000227 Phage integrase, N-terminal SAM-like domain; Region: Phage_integr_N; cl12235 663951000228 DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213 663951000229 active site 663951000230 DNA binding site [nucleotide binding] 663951000231 Int/Topo IB signature motif; other site 663951000232 HMMPfam hit to PF00589, Phage_integrase, score 1e-38 663951000233 Predicted helix-turn-helix motif with score 1150.000, SD 3.10 at aa 40-61, sequence INFNSIAKEANVSKSWLYKEHD 663951000234 aminoglycoside resistance protein; Provisional; Region: PRK13746 663951000235 Nucleotidyltransferase (NT) domain of Staphylococcus aureus kanamycin nucleotidyltransferase, and similar proteins; Region: NT_KNTase_like; cd05403 663951000236 active site 663951000237 NTP binding site [chemical binding]; other site 663951000238 metal binding triad [ion binding]; metal-binding site 663951000239 antibiotic binding site [chemical binding]; other site 663951000240 Domain of unknown function (DUF4111); Region: DUF4111; pfam13427 663951000241 HMMPfam hit to PF01909, NTP_transf_2, score 1.4e-15 663951000242 Ribosomal RNA adenine dimethylase; Region: RrnaAD; pfam00398 663951000243 S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440 663951000244 S-adenosylmethionine binding site [chemical binding]; other site 663951000245 HMMPfam hit to PF00398, RrnaAD, score 1.9e-108 663951000246 PS01131 Ribosomal RNA adenine dimethylases signature. 663951000247 S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440 663951000248 S-adenosylmethionine binding site [chemical binding]; other site 663951000249 HMMPfam hit to PF08242, Methyltransf_12, score 3.4e-22 663951000250 WYL domain; Region: WYL; pfam13280 663951000251 1 probable transmembrane helix predicted for SATW20_00460 by TMHMM2.0 at aa 13-35 663951000252 2 probable transmembrane helices predicted for SATW20_00470 by TMHMM2.0 at aa 72-94 and 104-126 663951000253 1 probable transmembrane helix predicted for SATW20_00480 by TMHMM2.0 at aa 4-26 663951000254 PS00018 EF-hand calcium-binding domain. 663951000255 Probable gene remnant. Similar to C-terminal region of Staphylococcus aureus (strain MSSA476) subname: full=putative uncharacterized protein UniProt:Q6GD61 (EMBL:BX571857) (167 aa) fasta scores: E()=3.1e-08, 75.7% id in 37 aa 663951000256 Lysis protein; Region: Lysis_col; pfam02402 663951000257 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 663951000258 HMMPfam hit to PF03413, PepSY, score 0.0037 663951000259 Probable gene remnant. CDS is truncated by the insertion of the upstream IS431 element 663951000260 HMMPfam hit to PF04851, ResIII, score 7e-11 663951000261 Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3316 663951000262 Integrase core domain; Region: rve; pfam00665 663951000263 HMMPfam hit to PF00665, rve, score 3.4e-18 663951000264 Predicted helix-turn-helix motif with score 980.000,SD 2.52 at aa 31-52, sequence ISEILRERGVNVHHSTVYRWVQ 663951000265 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes [Energy production and conversion]; Region: Lpd; COG1249 663951000266 Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070 663951000267 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852 663951000268 HMMPfam hit to PF07992, Pyr_redox_2, score 1.3e-40 663951000269 HMMPfam hit to PF00070, Pyr_redox, score 2.3e-27 663951000270 HMMPfam hit to PF02852, Pyr_redox_dim, score 1.4e-35 663951000271 Helix-Turn-Helix DNA binding domain of the MerR1 transcription regulator; Region: HTH_MerR1; cd04783 663951000272 Hg(II)-responsive transcriptional regulator; Region: MerR; TIGR02051 663951000273 DNA binding residues [nucleotide binding] 663951000274 dimer interface [polypeptide binding]; other site 663951000275 mercury binding site [ion binding]; other site 663951000276 Predicted helix-turn-helix motif with score 2172.000, SD 6.58 at aa 3-24, sequence MKISELAKACDVNKETVRYYER 663951000277 HMMPfam hit to PF00376, MerR, score 1.5e-12 663951000278 PS00552 Bacterial regulatory proteins, merR family signature. 663951000279 HMMPfam hit to PF09278, MerR-DNA-bind, score 9.7e-15 663951000280 TlpA-like family; composed of TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a...; Region: TlpA_like_family; cd02966 663951000281 Thioredoxin-like; Region: Thioredoxin_8; pfam13905 663951000282 catalytic residues [active] 663951000283 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 663951000284 HMMPfam hit to PF00578, AhpC-TSA, score 0.0007 663951000285 Cytochrome c biogenesis protein [Posttranslational modification, protein turnover, chaperones]; Region: CcdA; COG0785 663951000286 6 probable transmembrane helices predicted for SATW20_00580 by TMHMM2.0 at aa 6-28, 49-71, 81-103,124-146, 161-183 and 196-218 663951000287 HMMPfam hit to PF02683, DsbD, score 1.5e-05 663951000288 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 663951000289 2 probable transmembrane helices predicted for SATW20_00590 by TMHMM2.0 at aa 31-53 and 73-95 663951000290 Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371 663951000291 metal-binding site [ion binding] 663951000292 mercuric reductase; Region: MerA; TIGR02053 663951000293 Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070 663951000294 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852 663951000295 HMMPfam hit to PF00403, HMA, score 1.9e-11 663951000296 PS01047 Heavy-metal-associated domain. 663951000297 HMMPfam hit to PF07992, Pyr_redox_2, score 7.4e-66 663951000298 PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 663951000299 HMMPfam hit to PF00070, Pyr_redox, score 1.7e-33 663951000300 HMMPfam hit to PF02852, Pyr_redox_dim, score 8.2e-50 663951000301 alkylmercury lyase; Provisional; Region: PRK13239 663951000302 Helix-turn-helix domain of alkylmercury lyase; Region: HTH_15; pfam12324 663951000303 Alkylmercury lyase; Region: MerB; pfam03243 663951000304 HMMPfam hit to PF03243, MerB, score 8e-151 663951000305 Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3316 663951000306 Integrase core domain; Region: rve; pfam00665 663951000307 HMMPfam hit to PF00665, rve, score 3.2e-18 663951000308 Predicted helix-turn-helix motif with score 980.000,SD 2.52 at aa 31-52, sequence ISEILRERGVNVHHSTVYRWVQ 663951000309 SCCmec type III 663951000310 Protein of unknown function (DUF3021); Region: DUF3021; pfam11457 663951000311 Probable gene remnant. CDS is truncated by the insertion of the upstream IS431 element 663951000312 1 probable transmembrane helix predicted for SATW20_00640 by TMHMM2.0 at aa 55-77 663951000313 HMMPfam hit to PF04397, LytTR, score 9.5e-09 663951000314 Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3316 663951000315 Integrase core domain; Region: rve; pfam00665 663951000316 HMMPfam hit to PF00665, rve, score 4.4e-18 663951000317 Predicted helix-turn-helix motif with score 980.000,SD 2.52 at aa 31-52, sequence ISEILRERGVNVHHSTVYRWVQ 663951000318 pT181 663951000319 drug resistance transporter, EmrB/QacA subfamily; Region: efflux_EmrB; TIGR00711 663951000320 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 663951000321 putative substrate translocation pore; other site 663951000322 14 probable transmembrane helices predicted for SATW20_00660 by TMHMM2.0 at aa 12-34, 49-68, 81-100,105-127, 140-162, 166-188, 201-218, 223-240, 261-283,293-315, 322-344, 348-370, 391-413 and 428-450 663951000323 HMMPfam hit to PF07690, MFS_1, score 1.7e-43 663951000324 Plasmid recombination enzyme; Region: Mob_Pre; pfam01076 663951000325 HMMPfam hit to PF01076, Mob_Pre, score 2.5e-116 663951000326 CDS contains a frameshift after codon 28. Frameshift is due to a bp insertion 663951000327 HMMPfam hit to PF02486, Rep_trans, score 1.2e-65 663951000328 Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3316 663951000329 Integrase core domain; Region: rve; pfam00665 663951000330 HMMPfam hit to PF00665, rve, score 3.4e-18 663951000331 Predicted helix-turn-helix motif with score 980.000,SD 2.52 at aa 31-52, sequence ISEILRERGVNVHHSTVYRWVQ 663951000332 3-hydroxy-3-methylglutaryl CoA synthase [Lipid metabolism]; Region: PksG; COG3425 663951000333 1 probable transmembrane helix predicted for SATW20_00710 by TMHMM2.0 at aa 39-58 663951000334 Glycerophosphoryl diester phosphodiesterase [Energy production and conversion]; Region: UgpQ; COG0584 663951000335 Glycerophosphodiester phosphodiesterase domain in Escherichia coli cytosolic glycerophosphodiester phosphodiesterase UgpQ and similar proteins; Region: GDPD_EcUgpQ_like; cd08562 663951000336 putative active site [active] 663951000337 catalytic site [active] 663951000338 putative metal binding site [ion binding]; other site 663951000339 HMMPfam hit to PF03009, GDPD, score 7.6e-50 663951000340 YdeM is a Bacillus subtilis protein that belongs to a family of prokaryotic proteins of unkown function. YdeM has sequence similarity to the hot-dog fold of (R)-specific enoyl-CoA hydratase. Other enzymes with this fold include the peroxisomal...; Region: YdeM; cd03454 663951000341 putative active site [active] 663951000342 putative catalytic site [active] 663951000343 HMMPfam hit to PF01575, MaoC_dehydratas, score 1.4e-42 663951000344 NTF2-like N-terminal transpeptidase domain; Region: MecA_N; pfam05223 663951000345 Cell division protein FtsI/penicillin-binding protein 2 [Cell envelope biogenesis, outer membrane]; Region: FtsI; COG0768 663951000346 Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717 663951000347 Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905 663951000348 HMMPfam hit to PF00905, Transpeptidase, score 2.9e-102 663951000349 HMMPfam hit to PF03717, PBP_dimer, score 3.3e-55 663951000350 HMMPfam hit to PF05223, MecA_N, score 5.1e-46 663951000351 1 probable transmembrane helix predicted for SATW20_00740 by TMHMM2.0 at aa 7-24 663951000352 Antirepressor regulating drug resistance, predicted signal transduction N-terminal membrane component [Transcription / Signal transduction mechanisms]; Region: MecR1; COG4219 663951000353 Beta-lactamase class D [Defense mechanisms]; Region: COG2602 663951000354 2 probable transmembrane helices predicted for SATW20_00750 by TMHMM2.0 at aa 5-27 and 69-91 663951000355 HMMPfam hit to PF05569, Peptidase_M56, score 2.8e-60 663951000356 HMMPfam hit to PF00905, Transpeptidase, score 2.4e-68 663951000357 CDS contains a nonsense mutation (ochre) after codon 67. Similar to Staphylococcus aureus methicillin resistance regulatory protein MecI UniProt:P68262 (EMBL:L14020) (123 aa) fasta scores: E()=2.3e-43, 99.187% id in 123 aa 663951000358 HMMPfam hit to PF03965, Pencillinase_R, score 1.2e-24 663951000359 Transcriptional regulators [Transcription]; Region: MarR; COG1846 663951000360 MarR family; Region: MarR_2; pfam12802 663951000361 Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940 663951000362 Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012 663951000363 nucleotide binding site [chemical binding]; other site 663951000364 Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037 663951000365 HMMPfam hit to PF01047, MarR, score 1.5e-05 663951000366 Predicted helix-turn-helix motif with score 1609.000, SD 4.67 at aa 13-45, sequence RVLREIYNHHNISRTQISKNLEINKATISSILN 663951000367 HMMPfam hit to PF00480, ROK, score 1.2e-52 663951000368 PS01125 ROK family signature. 663951000369 Zn-dependent hydrolases, including glyoxylases [General function prediction only]; Region: GloB; COG0491 663951000370 Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158 663951000371 active site residue [active] 663951000372 Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158 663951000373 active site residue [active] 663951000374 HMMPfam hit to PF00581, Rhodanese, score 2.1e-05 663951000375 HMMPfam hit to PF00753, Lactamase_B, score 5.2e-19 663951000376 Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158 663951000377 active site residue [active] 663951000378 SirA_RHOD_Pry_redox. SirA-like domain located within a multidomain protein of unknown function. Other domains include RHOD (rhodanese homology domain), and Pry_redox (pyridine nucleotide-disulphide oxidoreductase) as well as a C-terminal domain that...; Region: SirA_RHOD_Pry_redox; cd03420 663951000379 CPxP motif; other site 663951000380 DsrE/DsrF/DrsH-like family; Region: DrsE_2; pfam13686 663951000381 HMMPfam hit to PF01206, SirA, score 1.1e-07 663951000382 HMMPfam hit to PF00581, Rhodanese, score 5.2e-09 663951000383 Uncharacterized protein YrkD from Bacillus subtilis and related domains; this domain superfamily was previously known as part of DUF156; Region: BsYrkD-like_DUF156; cd10155 663951000384 putative homodimer interface [polypeptide binding]; other site 663951000385 putative homotetramer interface [polypeptide binding]; other site 663951000386 putative metal binding site [ion binding]; other site 663951000387 putative homodimer-homodimer interface [polypeptide binding]; other site 663951000388 putative allosteric switch controlling residues; other site 663951000389 HMMPfam hit to PF02583, DUF156, score 1.4e-25 663951000390 HMMPfam hit to PF01925, DUF81, score 1.9e-12 663951000391 6 probable transmembrane helices predicted for SATW20_00810 by TMHMM2.0 at aa 10-32, 34-56, 81-103,108-125, 140-171 and 178-196 663951000392 A staphylococcus aureus chromosomal element encoding cadmium resistance determinants, and genes resembling the transposases genes of Tn554 663951000393 cadmium resistance transporter (or sequestration) family protein; Region: cad; TIGR00779 663951000394 Cadmium resistance transporter; Region: Cad; pfam03596 663951000395 HMMPfam hit to PF03596, Cad, score 3.9e-135 663951000396 6 probable transmembrane helices predicted for SATW20_00820 by TMHMM2.0 at aa 4-26, 38-60, 64-86, 98-120,135-157 and 178-200 663951000397 Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371 663951000398 metal-binding site [ion binding] 663951000399 Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371 663951000400 Cation transport ATPase [Inorganic ion transport and metabolism]; Region: ZntA; COG2217 663951000401 metal-binding site [ion binding] 663951000402 E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122 663951000403 Soluble P-type ATPase [General function prediction only]; Region: COG4087 663951000404 7 probable transmembrane helices predicted for SATW20_00830 by TMHMM2.0 at aa 184-201, 208-230, 245-267,406-428, 443-465, 749-771 and 776-798 663951000405 HMMPfam hit to PF00702, Hydrolase, score 2.7e-37 663951000406 PS00154 E1-E2 ATPases phosphorylation site. 663951000407 HMMPfam hit to PF00122, E1-E2_ATPase, score 4.1e-105 663951000408 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 663951000409 HMMPfam hit to PF00403, HMA, score 1.8e-10 663951000410 PS01047 Heavy-metal-associated domain. 663951000411 HMMPfam hit to PF00403, HMA, score 1.9e-09 663951000412 PS01047 Heavy-metal-associated domain. 663951000413 Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090 663951000414 dimerization interface [polypeptide binding]; other site 663951000415 putative DNA binding site [nucleotide binding]; other site 663951000416 putative Zn2+ binding site [ion binding]; other site 663951000417 HMMPfam hit to PF01022, HTH_5, score 1.7e-18 663951000418 PS00846 Bacterial regulatory proteins, arsR family signature. 663951000419 Predicted helix-turn-helix motif with score 1150.000, SD 3.10 at aa 40-61, sequence INFNSIAKEANVSKSWLYKEHD 663951000420 tyrosine recombinase XerC; Region: recomb_XerC; TIGR02224 663951000421 Phage integrase, N-terminal SAM-like domain; Region: Phage_integr_N; cl12235 663951000422 DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213 663951000423 active site 663951000424 DNA binding site [nucleotide binding] 663951000425 Int/Topo IB signature motif; other site 663951000426 HMMPfam hit to PF00589, Phage_integrase, score 1e-38 663951000427 Mov34/MPN/PAD-1 family; Region: MPN_DUF2466; cd08071 663951000428 MPN+ (JAMM) motif; other site 663951000429 Zinc-binding site [ion binding]; other site 663951000430 HMMPfam hit to PF04002, RadC, score 2.8e-12 663951000431 PS01302 DNA repair protein radC family signature. 663951000432 Protein of unknown function (DUF1643); Region: DUF1643; cl01787 663951000433 HMMPfam hit to PF07799, DUF1643, score 1.8e-73 663951000434 Staphylococcal protein of unknown function (DUF960); Region: DUF960; pfam06124 663951000435 HMMPfam hit to PF06124, DUF960, score 2.3e-79 663951000436 Staphylococcus protein of unknown function (DUF950); Region: DUF950; pfam06106 663951000437 Site-specific recombinases, DNA invertase Pin homologs [DNA replication, recombination, and repair]; Region: PinR; COG1961 663951000438 Serine Recombinase (SR) family, Resolvase and Invertase subfamily, catalytic domain; members contain a C-terminal DNA binding domain. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and...; Region: SR_ResInv; cd03768 663951000439 catalytic residues [active] 663951000440 catalytic nucleophile [active] 663951000441 Presynaptic Site I dimer interface [polypeptide binding]; other site 663951000442 Synaptic Antiparallel dimer interface [polypeptide binding]; other site 663951000443 Synaptic Flat tetramer interface [polypeptide binding]; other site 663951000444 Synaptic Site I dimer interface [polypeptide binding]; other site 663951000445 DNA binding site [nucleotide binding] 663951000446 Recombinase; Region: Recombinase; pfam07508 663951000447 Recombinase zinc beta ribbon domain; Region: Zn_ribbon_recom; pfam13408 663951000448 HMMPfam hit to PF04606, Ogr_Delta, score 2.2e-12 663951000449 HMMPfam hit to PF07508, Recombinase, score 3.3e-40 663951000450 HMMPfam hit to PF00239, Resolvase, score 1.5e-54 663951000451 PS00397 Site-specific recombinases active site. 663951000452 Site-specific recombinases, DNA invertase Pin homologs [DNA replication, recombination, and repair]; Region: PinR; COG1961 663951000453 Serine Recombinase family, catalytic domain; a DNA binding domain may be present either N- or C-terminal to the catalytic domain. These enzymes perform site-specific recombination of DNA molecules by a concerted, four-strand cleavage and rejoining...; Region: Ser_Recombinase; cd00338 663951000454 catalytic residues [active] 663951000455 catalytic nucleophile [active] 663951000456 Recombinase; Region: Recombinase; pfam07508 663951000457 Recombinase zinc beta ribbon domain; Region: Zn_ribbon_recom; pfam13408 663951000458 HMMPfam hit to PF07508, Recombinase, score 5.5e-27 663951000459 HMMPfam hit to PF00239, Resolvase, score 1.3e-41 663951000460 Domain of unknown function (DUF927); Region: DUF927; pfam06048 663951000461 HMMPfam hit to PF06048, DUF927, score 2.3e-240 663951000462 PS00017 ATP/GTP-binding site motif A (P-loop). 663951000463 Domain of unknown function (DUF1413); Region: DUF1413; pfam07205 663951000464 HMMPfam hit to PF07205, DUF1413, score 1e-77 663951000465 VIP2; A family of actin-ADP-ribosylating toxin. A member of the Bacillus-prodiced vegetative insecticidal proteins (VIPs) possesses high specificity against the major insect pest, corn rootworms, and belongs to a classs of binary toxins and regulators of...; Region: VIP2; cl00173 663951000466 The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009 663951000467 ATPases associated with a variety of cellular activities; Region: AAA; smart00382 663951000468 Walker A motif; other site 663951000469 ATP binding site [chemical binding]; other site 663951000470 Walker B motif; other site 663951000471 arginine finger; other site 663951000472 HMMPfam hit to PF07728, AAA_5, score 5.9e-32 663951000473 PS00017 ATP/GTP-binding site motif A (P-loop). 663951000474 5-methylcytosine-specific restriction enzyme subunit McrC; Provisional; Region: PRK09736 663951000476 Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cd01292 663951000477 active site 663951000478 HMMPfam hit to PF04909, Amidohydro_2, score 2.1e-33 663951000479 3 probable transmembrane helices predicted for SATW20_01030 by TMHMM2.0 at aa 46-63, 70-87 and 102-119 663951000480 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 663951000481 Major Facilitator Superfamily; Region: MFS_1; pfam07690 663951000482 putative substrate translocation pore; other site 663951000483 14 probable transmembrane helices predicted for SATW20_01040 by TMHMM2.0 at aa 17-39, 54-76, 83-105,115-133, 145-167, 172-194, 207-229, 233-250, 271-293,308-325, 332-354, 364-386, 407-424 and 439-461 663951000484 HMMPfam hit to PF07690, MFS_1, score 1.3e-53 663951000485 Probable gene remnant. Similar to the N-terminal region of sseveral protein including Staphylococcus haemolyticus (strain JCSC1435) N-hydroxyarylamine o-acetyltransferase/arylamine N-acetyltransferase UniProt:Q4L9Q9 (EMBL:AP006716) (261 aa) fasta scores: E()=3.2e-26, 42.9% id in 170 aa 663951000486 HMMPfam hit to PF00797, Acetyltransf_2, score 3.4e-06 663951000487 Transcriptional regulator [Transcription]; Region: AcrR; COG1309 663951000488 Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440 663951000489 Predicted helix-turn-helix motif with score 1706.000, SD 5.00 at aa 36-57, sequence KKMSDIAKISGVGVGTLYRHFE 663951000490 HMMPfam hit to PF00440, TetR_N, score 1.9e-08 663951000491 N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301 663951000492 Coenzyme A binding pocket [chemical binding]; other site 663951000493 HMMPfam hit to PF00583, Acetyltransf_1, score 6.9e-12 663951000494 tRNA-dihydrouridine synthase [Translation, ribosomal structure and biogenesis]; Region: COG0042 663951000495 Dihydrouridine synthase-like (DUS-like) FMN-binding domain. Members of this family catalyze the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also...; Region: DUS_like_FMN; cd02801 663951000496 FMN binding site [chemical binding]; other site 663951000497 active site 663951000498 catalytic residues [active] 663951000499 substrate binding site [chemical binding]; other site 663951000500 HMMPfam hit to PF01207, Dus, score 1.7e-31 663951000501 PS01136 Uncharacterized protein family UPF0034 signature. 663951000502 1 probable transmembrane helix predicted for SATW20_01090 by TMHMM2.0 at aa 15-37 663951000503 Regulator of competence-specific genes [Transcription]; Region: TfoX; COG3070 663951000504 HMMPfam hit to PF04993, TfoX_N, score 3.4e-34 663951000505 5 probable transmembrane helices predicted for SATW20_01110 by TMHMM2.0 at aa 5-27, 52-74, 84-106, 118-140 and 160-179 663951000506 Superfamily I DNA and RNA helicases and helicase subunits [DNA replication, recombination, and repair]; Region: COG1112 663951000507 Part of AAA domain; Region: AAA_19; pfam13245 663951000508 AAA domain; Region: AAA_12; pfam13087 663951000509 PS00017 ATP/GTP-binding site motif A (P-loop). 663951000510 4 probable transmembrane helices predicted for SATW20_01130 by TMHMM2.0 at aa 33-55, 59-81, 102-124 and 139-156 663951000511 Catalytic domain of Bacillus cereus phosphatidylinositol-specific phospholipases C and similar proteins; Region: PI-PLCc_BcPLC_like; cd08586 663951000512 active site 663951000513 catalytic site [active] 663951000514 putative metal binding site [ion binding]; other site 663951000515 1 probable transmembrane helix predicted for SATW20_01140 by TMHMM2.0 at aa 7-24 663951000516 HMMPfam hit to PF00388, PI-PLC-X, score 1.6e-68 663951000517 Protein of unknown function, DUF576; Region: DUF576; pfam04507 663951000518 HMMPfam hit to PF04507, DUF576, score 4.9e-173 663951000519 1 probable transmembrane helix predicted for SATW20_01150 by TMHMM2.0 at aa 5-27 663951000520 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 663951000521 AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207 663951000522 Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165 663951000523 Beta-xylosidase [Carbohydrate transport and metabolism]; Region: XynB; COG3664 663951000524 HMMPfam hit to PF00165, HTH_AraC, score 3.3e-06 663951000525 Predicted helix-turn-helix motif with score 1860.000, SD 5.52 at aa 172-193, sequence LSLSELSEYVGWSESHLSKKFA 663951000526 HMMPfam hit to PF00165, HTH_AraC, score 5.4e-08 663951000527 Metal-dependent amidase/aminoacylase/carboxypeptidase [General function prediction only]; Region: AbgB; COG1473 663951000528 M20 Peptidase Aminoacylase 1 family; Region: M20_Acy1; cd03886 663951000529 metal binding site [ion binding]; metal-binding site 663951000530 dimer interface [polypeptide binding]; other site 663951000531 HMMPfam hit to PF01546, Peptidase_M20, score 1.1e-52 663951000532 HMMPfam hit to PF07687, M20_dimer, score 4.4e-07 663951000533 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 663951000534 Major Facilitator Superfamily; Region: MFS_1; pfam07690 663951000535 putative substrate translocation pore; other site 663951000536 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 663951000537 14 probable transmembrane helices predicted for SATW20_01180 by TMHMM2.0 at aa 7-26, 46-68, 80-102,106-123, 136-158, 162-181, 201-223, 227-246, 267-289,295-317, 330-349, 353-375, 403-425 and 430-452 663951000538 HMMPfam hit to PF07690, MFS_1, score 1.1e-45 663951000539 PS00079 Multicopper oxidases signature 1. 663951000540 Na+/phosphate symporter [Inorganic ion transport and metabolism]; Region: NptA; COG1283 663951000541 Na+/Pi-cotransporter; Region: Na_Pi_cotrans; pfam02690 663951000542 Na+/Pi-cotransporter; Region: Na_Pi_cotrans; pfam02690 663951000543 PhoU domain; Region: PhoU; pfam01895 663951000544 9 probable transmembrane helices predicted for SATW20_01190 by TMHMM2.0 at aa 5-27, 53-75, 88-107,112-127, 134-156, 176-198, 210-232, 247-269 and 289-311 663951000545 HMMPfam hit to PF02690, Na_Pi_cotrans, score 2e-11 663951000546 HMMPfam hit to PF02690, Na_Pi_cotrans, score 1.2e-78 663951000547 Myosin-crossreactive antigen [Function unknown]; Region: COG4716 663951000548 HMMPfam hit to PF06100, Strep_67kDa_ant, score 0 663951000549 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 663951000550 Protein of unknown function (DUF1648); Region: DUF1648; pfam07853 663951000551 4 probable transmembrane helices predicted for SATW20_01210 by TMHMM2.0 at aa 7-26, 51-73, 94-116 and 126-148 663951000552 HMMPfam hit to PF07853, DUF1648, score 1.1e-16 663951000553 L-lactate permease [Energy production and conversion]; Region: LldP; COG1620 663951000554 L-lactate permease; Region: Lactate_perm; cl00701 663951000555 13 probable transmembrane helices predicted for SATW20_01220 by TMHMM2.0 at aa 12-34, 38-60, 67-89,127-149, 156-178, 193-215, 224-246, 250-267, 293-315,348-370, 391-413, 423-445 and 512-529 663951000556 HMMPfam hit to PF02652, Lactate_perm, score 6.7e-194 663951000557 PS00904 Protein prenyltransferases alpha subunit repeat signature. 663951000558 YSIRK type signal peptide; Region: YSIRK_signal; pfam04650 663951000559 B domain; Region: B; pfam02216 663951000560 B domain; Region: B; pfam02216 663951000561 B domain; Region: B; pfam02216 663951000562 B domain; Region: B; pfam02216 663951000563 Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118 663951000564 HMMPfam hit to PF00746, Gram_pos_anchor, score 5.2e-10 663951000565 PS00343 Gram-positive cocci surface proteins 'anchoring' hexapeptide. 663951000566 HMMPfam hit to PF01476, LysM, score 1e-14 663951000567 HMMPfam hit to PF03373, Octapeptide, score 1.5 663951000568 HMMPfam hit to PF03373, Octapeptide, score 0.72 663951000569 HMMPfam hit to PF03373, Octapeptide, score 0.72 663951000570 HMMPfam hit to PF03373, Octapeptide, score 0.72 663951000571 HMMPfam hit to PF03373, Octapeptide, score 0.56 663951000572 HMMPfam hit to PF03373, Octapeptide, score 0.72 663951000573 HMMPfam hit to PF03373, Octapeptide, score 0.34 663951000574 HMMPfam hit to PF03373, Octapeptide, score 0.87 663951000575 HMMPfam hit to PF02216, B, score 5.1e-33 663951000576 HMMPfam hit to PF02216, B, score 2.2e-34 663951000577 HMMPfam hit to PF02216, B, score 6.9e-34 663951000578 HMMPfam hit to PF02216, B, score 3.6e-34 663951000579 1 probable transmembrane helix predicted for SATW20_01230 by TMHMM2.0 at aa 12-34 663951000580 HMMPfam hit to PF04650, YSIRK_signal, score 1.1e-08 663951000581 staphylococcal accessory regulator family; Region: Staph_reg_Sar; TIGR01889 663951000582 Transcriptional regulators [Transcription]; Region: MarR; COG1846 663951000583 staphylococcal accessory regulator family; Region: Staph_reg_Sar; TIGR01889 663951000584 Transcriptional regulators [Transcription]; Region: MarR; COG1846 663951000585 HMMPfam hit to PF01047, MarR, score 0.00089 663951000586 iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577 663951000587 Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550 663951000588 ABC-ATPase subunit interface; other site 663951000589 dimer interface [polypeptide binding]; other site 663951000590 putative PBP binding regions; other site 663951000591 9 probable transmembrane helices predicted for SATW20_01250 by TMHMM2.0 at aa 13-35, 59-81, 94-111,115-137, 149-171, 196-213, 244-266, 281-303 and 310-329 663951000592 HMMPfam hit to PF01032, FecCD, score 1.6e-83 663951000593 iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577 663951000594 Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550 663951000595 ABC-ATPase subunit interface; other site 663951000596 dimer interface [polypeptide binding]; other site 663951000597 putative PBP binding regions; other site 663951000598 HMMPfam hit to PF01032, FecCD, score 1.2e-106 663951000599 9 probable transmembrane helices predicted for SATW20_01260 by TMHMM2.0 at aa 10-32, 62-81, 91-109,116-138, 148-170, 195-217, 237-259, 279-301 and 306-323 663951000600 Fe3+-siderophore binding domain FhuD. These proteins have been shown to function as initial receptors in ABC transport of Fe3+-siderophores in many eubacterial species. They belong to the TroA-like superfamily of helical backbone metal receptor proteins...; Region: FhuD; cd01146 663951000601 Periplasmic binding protein; Region: Peripla_BP_2; pfam01497 663951000602 siderophore binding site; other site 663951000603 HMMPfam hit to PF01497, Peripla_BP_2, score 4.1e-51 663951000604 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 663951000605 2,3-diaminopropionate biosynthesis protein SbnA; Region: PLP_SbnA_fam; TIGR03945 663951000606 CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS is a unique heme-containing enzyme that catalyzes a pyridoxal 5'-phosphate (PLP)-dependent condensation of serine and homocysteine to give cystathionine; Region: CBS_like; cd01561 663951000607 dimer interface [polypeptide binding]; other site 663951000608 pyridoxal 5'-phosphate binding site [chemical binding]; other site 663951000609 catalytic residue [active] 663951000610 HMMPfam hit to PF00291, PALP, score 4.3e-79 663951000611 2,3-diaminopropionate biosynthesis protein SbnB; Region: dehyd_SbnB_fam; TIGR03944 663951000612 ornithine cyclodeaminase; Validated; Region: PRK06823; cl17400 663951000613 HMMPfam hit to PF02423, OCD_Mu_crystall, score 5.6e-50 663951000614 Siderophore synthetase component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: RhbC; COG4264 663951000615 IucA / IucC family; Region: IucA_IucC; pfam04183 663951000616 Ferric iron reductase FhuF-like transporter; Region: FhuF; pfam06276 663951000617 HMMPfam hit to PF04183, IucA_IucC, score 1.2e-172 663951000618 drug efflux system protein MdtG; Provisional; Region: PRK09874 663951000619 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 663951000620 putative substrate translocation pore; other site 663951000621 10 probable transmembrane helices predicted for SATW20_01310 by TMHMM2.0 at aa 13-35, 50-72, 85-107,164-186, 222-244, 259-276, 288-307, 317-339, 346-368 and 378-397 663951000622 HMMPfam hit to PF07690, MFS_1, score 1.5e-44 663951000623 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 663951000624 Siderophore synthetase component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: RhbC; COG4264 663951000625 IucA / IucC family; Region: IucA_IucC; pfam04183 663951000626 Ferric iron reductase FhuF-like transporter; Region: FhuF; pfam06276 663951000627 HMMPfam hit to PF04183, IucA_IucC, score 6.2e-178 663951000628 Siderophore synthetase component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: RhbC; COG4264 663951000629 IucA / IucC family; Region: IucA_IucC; pfam04183 663951000630 Ferric iron reductase FhuF-like transporter; Region: FhuF; pfam06276 663951000631 HMMPfam hit to PF04183, IucA_IucC, score 1.1e-203 663951000632 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase [Carbohydrate transport and metabolism]; Region: HpcH; COG3836 663951000633 HMMPfam hit to PF03328, HpcH_HpaI, score 2.9e-28 663951000634 Diaminopimelate decarboxylase [Amino acid transport and metabolism]; Region: LysA; COG0019 663951000635 Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme PvsE; Region: PLPDE_III_PvsE_like; cd06843 663951000636 dimer interface [polypeptide binding]; other site 663951000637 active site 663951000638 pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site 663951000639 catalytic residues [active] 663951000640 substrate binding site [chemical binding]; other site 663951000641 HMMPfam hit to PF02784, Orn_Arg_deC_N, score 1.6e-23 663951000642 PS00879 Orn/DAP/Arg decarboxylases family 2 signature 2. 663951000643 HMMPfam hit to PF00278, Orn_DAP_Arg_deC, score 9.2e-24 663951000644 PS00213 Lipocalin signature. 663951000645 Stage 0 sporulation protein J (antagonist of Soj) containing ParB-like nuclease domain [Transcription]; Region: Spo0J; COG1475 663951000646 ParB-like nuclease domain; Region: ParBc; pfam02195 663951000647 HMMPfam hit to PF02195, ParBc, score 1.8e-09 663951000648 3 probable transmembrane helices predicted for SATW20_01370 by TMHMM2.0 at aa 20-42, 57-79 and 92-114 663951000649 acetoin reductase; Validated; Region: PRK08643 663951000650 meso-2,3-butanediol dehydrogenase-like, classical (c) SDRs; Region: meso-BDH-like_SDR_c; cd05366 663951000651 NAD binding site [chemical binding]; other site 663951000652 homotetramer interface [polypeptide binding]; other site 663951000653 homodimer interface [polypeptide binding]; other site 663951000654 active site 663951000655 substrate binding site [chemical binding]; other site 663951000656 HMMPfam hit to PF00106, adh_short, score 2.1e-35 663951000657 PS00061 Short-chain dehydrogenases/reductases family signature. 663951000658 Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931 663951000659 NAD dependent epimerase/dehydratase family; Region: Epimerase; pfam01370 663951000660 NAD(P) binding site [chemical binding]; other site 663951000661 active site 663951000662 HMMPfam hit to PF01370, Epimerase, score 1.5e-71 663951000663 Sugar transferases involved in lipopolysaccharide synthesis [Cell envelope biogenesis, outer membrane]; Region: WcaJ; COG2148 663951000664 exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase; Region: EPS_sugtrans; TIGR03025 663951000665 HMMPfam hit to PF02397, Bac_transf, score 4.8e-42 663951000666 1 probable transmembrane helix predicted for SATW20_01400 by TMHMM2.0 at aa 49-71 663951000667 Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438 663951000668 This family is most closely related to the GT1 family of glycosyltransferases. cap1E in Streptococcus pneumoniae is required for the synthesis of type 1 capsular polysaccharides; Region: GT1_cap1E_like; cd03808 663951000669 putative ADP-binding pocket [chemical binding]; other site 663951000670 HMMPfam hit to PF00534, Glycos_transf_1, score 1.6e-31 663951000671 12 probable transmembrane helices predicted for SATW20_01420 by TMHMM2.0 at aa 9-28, 32-54, 59-81, 91-113,120-142, 166-188, 195-217, 232-254, 290-312, 332-354,361-383 and 388-402 663951000672 HMMPfam hit to PF04932, Wzy_C, score 4.9e-13 663951000673 Membrane protein involved in the export of O-antigen and teichoic acid [General function prediction only]; Region: RfbX; COG2244 663951000674 Wzx, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Region: MATE_Wzx_like; cd13128 663951000675 HMMPfam hit to PF01943, Polysacc_synt, score 1e-32 663951000676 13 probable transmembrane helices predicted for SATW20_01430 by TMHMM2.0 at aa 43-65, 86-108, 113-135,142-161, 171-190, 221-243, 247-266, 292-314, 319-341,354-376, 380-399, 408-430 and 434-456 663951000677 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 663951000678 Superoxide dismutase [Inorganic ion transport and metabolism]; Region: SodA; COG0605 663951000679 Iron/manganese superoxide dismutases, alpha-hairpin domain; Region: Sod_Fe_N; pfam00081 663951000680 Iron/manganese superoxide dismutases, C-terminal domain; Region: Sod_Fe_C; pfam02777 663951000681 HMMPfam hit to PF00081, Sod_Fe_N, score 4.2e-49 663951000682 HMMPfam hit to PF02777, Sod_Fe_C, score 4.4e-69 663951000683 PS00088 Manganese and iron superoxide dismutases signature. 663951000684 HMMPfam hit to PF00746, Gram_pos_anchor, score 2.2e-05 663951000685 1 probable transmembrane helix predicted for SATW20_01450 by TMHMM2.0 at aa 192-214 663951000686 Transcriptional regulators [Transcription]; Region: PhnF; COG2188 663951000687 Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377 663951000688 DNA-binding site [nucleotide binding]; DNA binding site 663951000689 HMMPfam hit to PF00392, GntR, score 2.7e-18 663951000690 PS00043 Bacterial regulatory proteins, gntR family signature. 663951000691 Predicted helix-turn-helix motif with score 1559.000, SD 4.50 at aa 31-52, sequence PTEKELCARFDVSRMTLRQAIK 663951000692 purine nucleoside phosphorylase; Reviewed; Region: deoD; PRK05819 663951000693 Uridine phosphorylase [Nucleotide transport and metabolism]; Region: Udp; COG2820 663951000694 HMMPfam hit to PF01048, PNP_UDP_1, score 8e-86 663951000695 PS01232 Purine and other phosphorylases family 1 signature. 663951000696 Major Facilitator Superfamily; Region: MFS_1; pfam07690 663951000697 14 probable transmembrane helices predicted for SATW20_01480 by TMHMM2.0 at aa 12-34, 47-69, 76-98,102-124, 136-158, 163-185, 198-215, 220-237, 258-280,290-309, 321-340, 344-366, 379-401 and 421-443 663951000698 HMMPfam hit to PF07690, MFS_1, score 2.3e-40 663951000699 2-deoxyribose-5-phosphate aldolase (DERA) of the DeoC family; Region: DeoC; cd00959 663951000700 intersubunit interface [polypeptide binding]; other site 663951000701 active site 663951000702 catalytic residue [active] 663951000703 HMMPfam hit to PF01791, DeoC, score 7.4e-84 663951000704 phosphopentomutase; Provisional; Region: PRK05362 663951000705 Metalloenzyme superfamily; Region: Metalloenzyme; pfam01676 663951000706 HMMPfam hit to PF08342, PPM_N, score 3.7e-53 663951000707 PS00017 ATP/GTP-binding site motif A (P-loop). 663951000708 HMMPfam hit to PF01676, Metalloenzyme, score 3.7e-38 663951000709 phosphonate ABC transporter, permease protein PhnE; Region: PhnE; TIGR01097 663951000710 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 663951000711 dimer interface [polypeptide binding]; other site 663951000712 conserved gate region; other site 663951000713 putative PBP binding loops; other site 663951000714 ABC-ATPase subunit interface; other site 663951000715 HMMPfam hit to PF00528, BPD_transp_1, score 1.9e-09 663951000716 6 probable transmembrane helices predicted for SATW20_01510 by TMHMM2.0 at aa 23-45, 83-105, 117-139,191-208, 215-237 and 247-266 663951000717 phosphonate ABC transporter, permease protein PhnE; Region: PhnE; TIGR01097 663951000718 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 663951000719 dimer interface [polypeptide binding]; other site 663951000720 conserved gate region; other site 663951000721 ABC-ATPase subunit interface; other site 663951000722 HMMPfam hit to PF00528, BPD_transp_1, score 3.1e-16 663951000723 6 probable transmembrane helices predicted for SATW20_01520 by TMHMM2.0 at aa 21-43, 83-105, 118-140,145-164, 185-207 and 232-254 663951000724 ABC-type phosphate/phosphonate transport system, ATPase component [Inorganic ion transport and metabolism]; Region: COG3638 663951000725 ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; Region: ABC_PhnC_transporter; cd03256 663951000726 Walker A/P-loop; other site 663951000727 ATP binding site [chemical binding]; other site 663951000728 Q-loop/lid; other site 663951000729 ABC transporter signature motif; other site 663951000730 Walker B; other site 663951000731 D-loop; other site 663951000732 H-loop/switch region; other site 663951000733 HMMPfam hit to PF00005, ABC_tran, score 2e-53 663951000734 PS00211 ABC transporters family signature. 663951000735 PS00017 ATP/GTP-binding site motif A (P-loop). 663951000736 ABC-type phosphate/phosphonate transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: PhnD; COG3221 663951000737 Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cl17432 663951000738 HMMPfam hit to PF09084, NMT1, score 9.1e-10 663951000739 1 probable transmembrane helix predicted for SATW20_01540 by TMHMM2.0 at aa 7-26 663951000740 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 663951000741 ABC-type uncharacterized transport system; Region: ABC_transp_aux; pfam09822 663951000742 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases [Nucleotide transport and metabolism]; Region: UshA; COG0737 663951000743 Escherichia coli CpdB and related proteins, N-terminal metallophosphatase domain; Region: MPP_CpdB_N; cd07410 663951000744 active site 663951000745 metal binding site [ion binding]; metal-binding site 663951000746 5'-nucleotidase, C-terminal domain; Region: 5_nucleotid_C; pfam02872 663951000747 HMMPfam hit to PF00149, Metallophos, score 1.2e-12 663951000748 PS00786 5'-nucleotidase signature 2. 663951000749 HMMPfam hit to PF02872, 5_nucleotid_C, score 8.5e-45 663951000750 Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396 663951000751 Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093 663951000752 non-specific DNA binding site [nucleotide binding]; other site 663951000753 salt bridge; other site 663951000754 sequence-specific DNA binding site [nucleotide binding]; other site 663951000755 Predicted Zn peptidase [Amino acid transport and metabolism]; Region: COG2856 663951000756 HMMPfam hit to PF01381, HTH_3, score 3e-07 663951000757 Predicted helix-turn-helix motif with score 1894.000, SD 5.64 at aa 16-37, sequence LSRKELSEKINVSEQAIWQYET 663951000758 HMMPfam hit to PF06114, DUF955, score 7.1e-26 663951000759 bifunctional acetaldehyde-CoA/alcohol dehydrogenase; Provisional; Region: PRK13805 663951000760 Coenzyme A acylating aldehyde dehydrogenase (ACDH), ALDH family 20-like; Region: ALDH_F20_ACDH; cd07122 663951000761 putative catalytic cysteine [active] 663951000762 C-terminal alcohol dehydrogenase domain of the acetaldehyde dehydrogenase-alcohol dehydrogenase bifunctional two-domain protein (AAD); Region: AAD_C; cd08178 663951000763 putative active site [active] 663951000764 metal binding site [ion binding]; metal-binding site 663951000765 HMMPfam hit to PF00465, Fe-ADH, score 5.5e-145 663951000766 PS00913 Iron-containing alcohol dehydrogenases signature 1. 663951000767 PS00060 Iron-containing alcohol dehydrogenases signature 2. 663951000768 Capsular polysaccharide biosynthesis protein [Cell envelope biogenesis, outer membrane]; Region: COG3944 663951000769 polysaccharide export protein, MPA1 family, Gram-positive type; Region: polys_exp_MPA1; TIGR01006 663951000770 HMMPfam hit to PF02706, Wzz, score 2e-45 663951000771 2 probable transmembrane helices predicted for SATW20_01600 by TMHMM2.0 at aa 20-42 and 172-191 663951000772 capsular exopolysaccharide family; Region: eps_fam; TIGR01007 663951000773 The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203 663951000774 Capsular polysaccharide biosynthesis protein [Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: CapC; COG4464 663951000775 HMMPfam hit to PF02811, PHP, score 4.1e-35 663951000776 Predicted nucleoside-diphosphate sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: COG1086 663951000777 UDP-Glcnac (UDP-linked N-acetylglucosamine) inverting 4,6-dehydratase, extended (e) SDRs; Region: UDP_invert_4-6DH_SDR_e; cd05237 663951000778 NAD(P) binding site [chemical binding]; other site 663951000779 homodimer interface [polypeptide binding]; other site 663951000780 substrate binding site [chemical binding]; other site 663951000781 active site 663951000782 4 probable transmembrane helices predicted for SATW20_01630 by TMHMM2.0 at aa 10-32, 44-62, 77-99 and 104-126 663951000783 HMMPfam hit to PF02719, Polysacc_synt_2, score 1.2e-200 663951000784 UDP-N-acetylglucosamine 4,6-dehydratase/5-epimerase; Region: FnlA; TIGR04130 663951000785 UDP-Glcnac (UDP-linked N-acetylglucosamine) inverting 4,6-dehydratase, extended (e) SDRs; Region: UDP_invert_4-6DH_SDR_e; cd05237 663951000786 NAD(P) binding site [chemical binding]; other site 663951000787 homodimer interface [polypeptide binding]; other site 663951000788 substrate binding site [chemical binding]; other site 663951000789 active site 663951000790 Polysaccharide biosynthesis protein C-terminal; Region: Polysacc_syn_2C; pfam08485 663951000791 HMMPfam hit to PF02719, Polysacc_synt_2, score 7.2e-160 663951000792 HMMPfam hit to PF08485, Polysacc_syn_2C, score 1.8e-25 663951000793 capsular polysaccharide assembling protein (CAPF) like, extended (e) SDRs; Region: CAPF_like_SDR_e; cd05261 663951000794 NAD dependent epimerase/dehydratase family; Region: Epimerase; pfam01370 663951000795 putative NAD(P) binding site [chemical binding]; other site 663951000796 active site 663951000797 putative substrate binding site [chemical binding]; other site 663951000798 dTDP-4-dehydrorhamnose 3,5-epimerase and related enzymes [Cell envelope biogenesis, outer membrane]; Region: RfbC; COG1898 663951000799 HMMPfam hit to PF01370, Epimerase, score 1.4e-11 663951000800 UDP-N-acetylglucosamine 2-epimerase [Cell envelope biogenesis, outer membrane]; Region: WecB; COG0381 663951000801 Bacterial members of the UDP-N-Acetylglucosamine (GlcNAc) 2-Epimerase family are known to catalyze the reversible interconversion of UDP-GlcNAc and UDP-N-acetylmannosamine (UDP-ManNAc). The enzyme serves to produce an activated form of ManNAc residues; Region: GT1_UDP-GlcNAc_2-Epimerase; cd03786 663951000802 active site 663951000803 homodimer interface [polypeptide binding]; other site 663951000804 HMMPfam hit to PF02350, Epimerase_2, score 2.2e-169 663951000805 Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438 663951000806 Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013 663951000807 12 probable transmembrane helices predicted for SATW20_01680 by TMHMM2.0 at aa 5-22, 27-44, 56-75, 90-112,125-147, 174-196, 208-227, 231-248, 255-273, 376-398,411-428 and 432-454 663951000808 Maltose O-acyltransferase (MAT)-like: This family is composed of maltose O-acetyltransferase, galactoside O-acetyltransferase (GAT), xenobiotic acyltransferase (XAT) and similar proteins. MAT and GAT catalyze the CoA-dependent acetylation of the...; Region: LbH_MAT_like; cd04647 663951000809 trimer interface [polypeptide binding]; other site 663951000810 active site 663951000811 substrate binding site [chemical binding]; other site 663951000812 CoA binding site [chemical binding]; other site 663951000813 HMMPfam hit to PF00132, Hexapep, score 13 663951000814 HMMPfam hit to PF00132, Hexapep, score 3.3 663951000815 HMMPfam hit to PF00132, Hexapep, score 2.4 663951000816 Multidrug and toxic compound extrusion family and similar proteins; Region: MATE_like; cl09326 663951000817 HMMPfam hit to PF01943, Polysacc_synt, score 2.6e-05 663951000818 12 probable transmembrane helices predicted for SATW20_01700 by TMHMM2.0 at aa 13-35, 45-67, 80-102,106-128, 141-163, 167-186, 217-236, 240-262, 283-305,320-342, 354-371 and 381-403 663951000819 Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438 663951000820 This family is most closely related to the GT1 family of glycosyltransferases. wbuB in E. coli is involved in the biosynthesis of the O26 O-antigen. It has been proposed to function as an N-acetyl-L-fucosamine (L-FucNAc) transferase; Region: GT1_wbuB_like; cd03794 663951000821 HMMPfam hit to PF00534, Glycos_transf_1, score 2.4e-06 663951000822 Bacterial sugar transferase; Region: Bac_transf; pfam02397 663951000823 HMMPfam hit to PF02397, Bac_transf, score 3.4e-40 663951000824 1 probable transmembrane helix predicted for SATW20_01720 by TMHMM2.0 at aa 7-28 663951000825 UDP-glucose 4 epimerase, subgroup 4, extended (e) SDRs; Region: UDP_G4E_4_SDR_e; cd05232 663951000826 NAD dependent epimerase/dehydratase family; Region: Epimerase; pfam01370 663951000827 putative NAD(P) binding site [chemical binding]; other site 663951000828 active site 663951000829 putative substrate binding site [chemical binding]; other site 663951000830 HMMPfam hit to PF01370, Epimerase, score 7.7e-17 663951000831 UDP-N-acetyl-D-mannosaminuronate dehydrogenase [Cell envelope biogenesis, outer membrane]; Region: WecC; COG0677 663951000832 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; Region: 3HCDH_N; pfam02737 663951000833 UDP-glucose/GDP-mannose dehydrogenase family, central domain; Region: UDPG_MGDP_dh; pfam00984 663951000834 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain; Region: UDPG_MGDP_dh_C; pfam03720 663951000835 HMMPfam hit to PF03721, UDPG_MGDP_dh_N, score 3.3e-89 663951000836 PS00639 Eukaryotic thiol (cysteine) proteases histidine active site. 663951000837 HMMPfam hit to PF00984, UDPG_MGDP_dh, score 1.2e-46 663951000838 HMMPfam hit to PF03720, UDPG_MGDP_dh_C, score 2.1e-34 663951000839 UDP-N-acetylglucosamine 2-epimerase [Cell envelope biogenesis, outer membrane]; Region: WecB; COG0381 663951000840 Bacterial members of the UDP-N-Acetylglucosamine (GlcNAc) 2-Epimerase family are known to catalyze the reversible interconversion of UDP-GlcNAc and UDP-N-acetylmannosamine (UDP-ManNAc). The enzyme serves to produce an activated form of ManNAc residues; Region: GT1_UDP-GlcNAc_2-Epimerase; cd03786 663951000841 active site 663951000842 homodimer interface [polypeptide binding]; other site 663951000843 HMMPfam hit to PF02350, Epimerase_2, score 6.6e-195 663951000844 heme-degrading monooxygenase IsdI; Provisional; Region: PRK13313 663951000845 HMMPfam hit to PF03992, ABM, score 3e-11 663951000846 Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2832 663951000847 HMMPfam hit to PF04304, DUF454, score 5.5e-37 663951000848 3 probable transmembrane helices predicted for SATW20_01770 by TMHMM2.0 at aa 4-38, 76-93 and 98-115 663951000849 Uncharacterized Staphylococcus aureus AldA1 (SACOL0154) aldehyde dehydrogenase-like; Region: ALDH_StaphAldA1; cd07117 663951000850 Aldehyde dehydrogenase family; Region: Aldedh; pfam00171 663951000851 NAD(P) binding site [chemical binding]; other site 663951000852 catalytic residues [active] 663951000853 HMMPfam hit to PF00171, Aldedh, score 3.6e-241 663951000854 PS00687 Aldehyde dehydrogenases glutamic acid active site. 663951000855 PS00070 Aldehyde dehydrogenases cysteine active site. 663951000856 Co/Zn/Cd efflux system component [Inorganic ion transport and metabolism]; Region: CzcD; COG1230 663951000857 Predicted Co/Zn/Cd cation transporters [Inorganic ion transport and metabolism]; Region: MMT1; COG0053 663951000858 6 probable transmembrane helices predicted for SATW20_01790 by TMHMM2.0 at aa 30-52, 62-81, 94-116,131-153, 166-188 and 192-209 663951000859 HMMPfam hit to PF01545, Cation_efflux, score 6.3e-113 663951000860 Protein of unknown function (DUF4242); Region: DUF4242; pfam14026 663951000861 ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism]; Region: TauB; COG1116 663951000862 ATP-binding cassette domain of the nitrate and sulfonate transporters; Region: ABC_NrtD_SsuB_transporters; cd03293 663951000863 Walker A/P-loop; other site 663951000864 ATP binding site [chemical binding]; other site 663951000865 Q-loop/lid; other site 663951000866 ABC transporter signature motif; other site 663951000867 Walker B; other site 663951000868 D-loop; other site 663951000869 H-loop/switch region; other site 663951000870 HMMPfam hit to PF00005, ABC_tran, score 2.1e-58 663951000871 PS00017 ATP/GTP-binding site motif A (P-loop). 663951000872 ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components [Inorganic ion transport and metabolism]; Region: TauA; COG0715 663951000873 NMT1-like family; Region: NMT1_2; pfam13379 663951000874 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 663951000875 ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism]; Region: TauC; COG0600 663951000876 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cl00427 663951000877 6 probable transmembrane helices predicted for SATW20_01840 by TMHMM2.0 at aa 9-31, 35-57, 64-86, 116-138,180-202 and 222-241 663951000878 PS00017 ATP/GTP-binding site motif A (P-loop). 663951000879 HMMPfam hit to PF00528, BPD_transp_1, score 6.5e-25 663951000880 Acyl-CoA dehydrogenases [Lipid metabolism]; Region: CaiA; COG1960 663951000881 Acyl-CoA dehydrogenase; Region: ACAD; cl09933 663951000882 Uncharacterized conserved protein [Function unknown]; Region: COG5609 663951000883 formate dehydrogenase; Provisional; Region: PRK07574 663951000884 NAD-dependent Formate Dehydrogenase (FDH); Region: FDH; cd05302 663951000885 dimerization interface [polypeptide binding]; other site 663951000886 ligand binding site [chemical binding]; other site 663951000887 NAD binding site [chemical binding]; other site 663951000888 catalytic site [active] 663951000889 HMMPfam hit to PF00389, 2-Hacid_dh, score 1.9e-21 663951000890 HMMPfam hit to PF02826, 2-Hacid_dh_C, score 2.4e-71 663951000891 PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 663951000892 PS00670 D-isomer specific 2-hydroxyacid dehydrogenases signature 2. 663951000893 Na+/melibiose symporter and related transporters [Carbohydrate transport and metabolism]; Region: MelB; COG2211 663951000894 HMMPfam hit to PF07690, MFS_1, score 1.3e-25 663951000895 12 probable transmembrane helices predicted for SATW20_01880 by TMHMM2.0 at aa 13-32, 42-64, 71-90, 95-114,135-157, 162-184, 225-247, 270-292, 299-316, 320-342,355-377 and 387-409 663951000896 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 663951000897 The adenylation domain of nonribosomal peptide synthetases (NRPS), including Bacillus subtilis termination module Surfactin (SrfA-C); Region: A_NRPS_Srf_like; cd12117 663951000898 amino acid adenylation domain; Region: AA-adenyl-dom; TIGR01733 663951000899 acyl-activating enzyme (AAE) consensus motif; other site 663951000900 AMP binding site [chemical binding]; other site 663951000901 Phosphopantetheine attachment site; Region: PP-binding; pfam00550 663951000902 Condensation domain; Region: Condensation; pfam00668 663951000903 Non-ribosomal peptide synthetase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: EntF; COG1020 663951000904 HxxPF-repeated domain; Region: HxxPF_rpt; pfam13745 663951000905 The adenylation domain of nonribosomal peptide synthetases (NRPS); Region: A_NRPS; cd05930 663951000906 acyl-activating enzyme (AAE) consensus motif; other site 663951000907 AMP binding site [chemical binding]; other site 663951000908 Phosphopantetheine attachment site; Region: PP-binding; pfam00550 663951000909 thioester reductase domain; Region: Thioester-redct; TIGR01746 663951000910 Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931 663951000911 NAD(P) binding site [chemical binding]; other site 663951000912 active site 663951000913 HMMPfam hit to PF00501, AMP-binding, score 2.7e-134 663951000914 PS00455 Putative AMP-binding domain signature. 663951000915 HMMPfam hit to PF00550, PP-binding, score 4e-18 663951000916 PS00012 Phosphopantetheine attachment site. 663951000917 HMMPfam hit to PF00668, Condensation, score 2.1e-64 663951000918 HMMPfam hit to PF00501, AMP-binding, score 2.6e-115 663951000919 PS00697 ATP-dependent DNA ligase AMP-binding site. 663951000920 HMMPfam hit to PF00550, PP-binding, score 1.3e-12 663951000921 PS00012 Phosphopantetheine attachment site. 663951000922 HMMPfam hit to PF07993, NAD_binding_4, score 1.5e-23 663951000923 Phosphopantetheinyl transferase [Coenzyme metabolism]; Region: Sfp; COG2091 663951000924 4'-phosphopantetheinyl transferase superfamily; Region: ACPS; pfam01648 663951000925 HMMPfam hit to PF01648, ACPS, score 0.0011 663951000926 Predicted periplasmic/secreted protein [Function unknown]; Region: COG3477 663951000927 4 probable transmembrane helices predicted for SATW20_01910 by TMHMM2.0 at aa 7-29, 69-91, 103-125 and 140-158 663951000928 HMMPfam hit to PF07274, DUF1440, score 6.1e-104 663951000929 AAK_NAGK-like: N-Acetyl-L-glutamate kinase (NAGK)-like . Included in this CD are the Escherichia coli and Pseudomonas aeruginosa type NAGKs which catalyze the phosphorylation of N-acetyl-L-glutamate (NAG) by ATP in the second step of arginine...; Region: AAK_NAGK-like; cd04238 663951000930 nucleotide binding site [chemical binding]; other site 663951000931 N-acetyl-L-glutamate binding site [chemical binding]; other site 663951000932 HMMPfam hit to PF00696, AA_kinase, score 1.7e-31 663951000933 Ornithine acetyltransferase (OAT) family; also referred to as ArgJ. OAT catalyzes the first and fifth steps in arginine biosynthesis, coupling acetylation of glutamate with deacetylation of N-acetylornithine, which allows recycling of the acetyl group in...; Region: OAT; cd02152 663951000934 heterotetramer interface [polypeptide binding]; other site 663951000935 active site pocket [active] 663951000936 cleavage site 663951000937 HMMPfam hit to PF01960, ArgJ, score 3.9e-194 663951000938 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 663951000939 N-acetyl-gamma-glutamyl-phosphate reductase, common form; Region: argC; TIGR01850 663951000940 Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859 663951000941 HMMPfam hit to PF02774, Semialdhyde_dhC, score 1.2e-41 663951000942 PS01224 N-acetyl-gamma-glutamyl-phosphate reductase active site. 663951000943 HMMPfam hit to PF01118, Semialdhyde_dh, score 4.9e-44 663951000944 ornithine--oxo-acid transaminase; Provisional; Region: rocD; PRK04073 663951000945 Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610 663951000946 inhibitor-cofactor binding pocket; inhibition site 663951000947 pyridoxal 5'-phosphate binding site [chemical binding]; other site 663951000948 catalytic residue [active] 663951000949 HMMPfam hit to PF00202, Aminotran_3, score 3.2e-161 663951000950 PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 663951000951 Branched-chain amino acid transport protein; Region: Branch_AA_trans; pfam05525 663951000952 HMMPfam hit to PF05525, Branch_AA_trans, score 2.5e-239 663951000953 12 probable transmembrane helices predicted for SATW20_01960 by TMHMM2.0 at aa 12-31, 41-63, 84-106,121-140, 153-175, 195-217, 238-260, 275-297, 318-340,344-366, 373-390 and 422-441 663951000954 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 663951000955 Isochorismatase family; Region: Isochorismatase; pfam00857 663951000956 Cysteine hydrolases; This family contains amidohydrolases, like CSHase (N-carbamoylsarcosine amidohydrolase), involved in creatine metabolism and nicotinamidase, converting nicotinamide to nicotinic acid and ammonia in the pyridine nucleotide cycle. It...; Region: cysteine_hydrolases; cd00431 663951000957 catalytic triad [active] 663951000958 conserved cis-peptide bond; other site 663951000959 HMMPfam hit to PF00857, Isochorismatase, score 2.8e-45 663951000960 Pyruvate decarboxylase and related thiamine pyrophosphate-requiring enzymes [Carbohydrate transport and metabolism / Coenzyme metabolism / General function prediction only]; Region: COG3961 663951000961 Pyrimidine (PYR) binding domain of pyruvate decarboxylase (PDC), indolepyruvate decarboxylase (IPDC) and related proteins; Region: TPP_PYR_PDC_IPDC_like; cd07038 663951000962 dimer interface [polypeptide binding]; other site 663951000963 PYR/PP interface [polypeptide binding]; other site 663951000964 TPP binding site [chemical binding]; other site 663951000965 Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205 663951000966 Thiamine pyrophosphate (TPP) family, PDC_IPDC subfamily, TPP-binding module; composed of proteins similar to pyruvate decarboxylase (PDC) and indolepyruvate decarboxylase (IPDC). PDC, a key enzyme in alcoholic fermentation, catalyzes the conversion of...; Region: TPP_PDC_IPDC; cd02005 663951000967 TPP-binding site [chemical binding]; other site 663951000968 dimer interface [polypeptide binding]; other site 663951000969 HMMPfam hit to PF02775, TPP_enzyme_C, score 2.8e-16 663951000970 HMMPfam hit to PF00205, TPP_enzyme_M, score 9.3e-20 663951000971 HMMPfam hit to PF02776, TPP_enzyme_N, score 1.3e-54 663951000972 Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263 663951000973 PTS system, glucose-specific IIBC component; Region: PTS-II-BC-glcB; TIGR02002 663951000974 PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212 663951000975 active site turn [active] 663951000976 phosphorylation site [posttranslational modification] 663951000977 PTS_IIA, PTS system, glucose/sucrose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_glc; cd00210 663951000978 HPr interaction site; other site 663951000979 glycerol kinase (GK) interaction site [polypeptide binding]; other site 663951000980 active site 663951000981 phosphorylation site [posttranslational modification] 663951000982 HMMPfam hit to PF00358, PTS_EIIA_1, score 1.8e-77 663951000983 PS00371 PTS EIIA domains phosphorylation site signature 1. 663951000984 HMMPfam hit to PF00367, PTS_EIIB, score 3.2e-17 663951000985 PS01035 PTS EIIB domains cysteine phosphorylation site signature. 663951000986 10 probable transmembrane helices predicted for SATW20_01990 by TMHMM2.0 at aa 12-34, 74-96, 126-148,170-192, 197-219, 278-296, 303-321, 326-348, 355-374 and 380-402 663951000987 HMMPfam hit to PF02378, PTS_EIIC, score 8.1e-122 663951000988 Uncharacterized conserved protein [Function unknown]; Region: COG3589 663951000989 Bacterial protein of unknown function (DUF871); Region: DUF871; pfam05913 663951000990 HMMPfam hit to PF05913, DUF871, score 5.6e-186 663951000991 Predicted sugar phosphate isomerase [General function prediction only]; Region: COG2103 663951000992 N-acetylmuramic acid 6-phosphate etherase. Members of this family contain the SIS (Sugar ISomerase) domain. The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. The bacterial cell wall sugar N-acetylmuramic acid...; Region: SIS_Etherase; cd05007 663951000993 putative active site [active] 663951000994 PS00017 ATP/GTP-binding site motif A (P-loop). 663951000995 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 663951000996 PS01272 Glucokinase regulatory protein family signature. 663951000997 PTS system N-acetylmuramic acid transporter subunits EIIBC; Reviewed; Region: murP; PRK09586 663951000998 PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212 663951000999 active site turn [active] 663951001000 phosphorylation site [posttranslational modification] 663951001001 Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263 663951001002 HMMPfam hit to PF00367, PTS_EIIB, score 9.6e-15 663951001003 PS01035 PTS EIIB domains cysteine phosphorylation site signature. 663951001004 10 probable transmembrane helices predicted for SATW20_02020 by TMHMM2.0 at aa 132-154, 169-191, 204-226,236-255, 268-290, 305-327, 347-369, 384-401, 408-430 and 450-472 663951001005 HMMPfam hit to PF02378, PTS_EIIC, score 6e-39 663951001006 Transcriptional regulators [Transcription]; Region: RpiR; COG1737 663951001007 Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418 663951001008 RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013 663951001009 putative active site [active] 663951001010 HMMPfam hit to PF01418, HTH_6, score 1.8e-29 663951001011 HMMPfam hit to PF01380, SIS, score 2.5e-13 663951001012 3 probable transmembrane helices predicted for SATW20_02040 by TMHMM2.0 at aa 2-20, 30-52 and 65-87 663951001013 Type I site-specific restriction-modification system, R (restriction) subunit and related helicases [Defense mechanisms]; Region: COG0610 663951001014 Type I restriction enzyme R protein N terminus (HSDR_N); Region: HSDR_N; pfam04313 663951001015 DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046 663951001016 ATP binding site [chemical binding]; other site 663951001017 putative Mg++ binding site [ion binding]; other site 663951001018 HMMPfam hit to PF04313, HSDR_N, score 3.8e-47 663951001019 HMMPfam hit to PF04851, ResIII, score 1.3e-44 663951001020 PS00012 Phosphopantetheine attachment site. 663951001021 ATPase components of various ABC-type transport systems, contain duplicated ATPase [General function prediction only]; Region: COG1123 663951001022 ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257 663951001023 Walker A/P-loop; other site 663951001024 ATP binding site [chemical binding]; other site 663951001025 Q-loop/lid; other site 663951001026 ABC transporter signature motif; other site 663951001027 Walker B; other site 663951001028 D-loop; other site 663951001029 H-loop/switch region; other site 663951001030 Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; pfam08352 663951001031 ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257 663951001032 Walker A/P-loop; other site 663951001033 ATP binding site [chemical binding]; other site 663951001034 Q-loop/lid; other site 663951001035 ABC transporter signature motif; other site 663951001036 Walker B; other site 663951001037 D-loop; other site 663951001038 H-loop/switch region; other site 663951001039 HMMPfam hit to PF00005, ABC_tran, score 1.6e-63 663951001040 PS00211 ABC transporters family signature. 663951001041 PS00017 ATP/GTP-binding site motif A (P-loop). 663951001042 HMMPfam hit to PF08352, oligo_HPY, score 2.4e-05 663951001043 HMMPfam hit to PF00005, ABC_tran, score 5.8e-64 663951001044 PS00211 ABC transporters family signature. 663951001045 PS00017 ATP/GTP-binding site motif A (P-loop). 663951001046 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601 663951001047 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 663951001048 dimer interface [polypeptide binding]; other site 663951001049 conserved gate region; other site 663951001050 putative PBP binding loops; other site 663951001051 ABC-ATPase subunit interface; other site 663951001052 7 probable transmembrane helices predicted for SATW20_02080 by TMHMM2.0 at aa 88-110, 117-139, 206-228,241-263, 278-300, 336-358 and 386-408 663951001053 HMMPfam hit to PF00528, BPD_transp_1, score 1.5e-50 663951001054 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppC; COG1173 663951001055 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 663951001056 dimer interface [polypeptide binding]; other site 663951001057 conserved gate region; other site 663951001058 ABC-ATPase subunit interface; other site 663951001059 9 probable transmembrane helices predicted for SATW20_02090 by TMHMM2.0 at aa 15-34, 41-60, 75-97,125-147, 193-215, 228-247, 251-273, 311-333 and 353-375 663951001060 HMMPfam hit to PF00528, BPD_transp_1, score 4.1e-43 663951001061 The substrate-binding domain of an ABC-type nickel/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like; cl01709 663951001062 The substrate-binding domain of an ABC-type nickel/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like; cl01709 663951001063 Bacterial extracellular solute-binding proteins, family 5 Middle; Region: SBP_bac_5; pfam00496 663951001064 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 663951001065 HMMPfam hit to PF00496, SBP_bac_5, score 2.3e-05 663951001066 HMMPfam hit to PF00496, SBP_bac_5, score 5.3e-13 663951001067 Gamma-glutamyltransferase [Amino acid transport and metabolism]; Region: Ggt; COG0405 663951001068 Gamma-glutamyltranspeptidase; Region: G_glu_transpept; pfam01019 663951001069 HMMPfam hit to PF01019, G_glu_transpept, score 2e-228 663951001070 azoreductase; Reviewed; Region: PRK00170 663951001071 NADPH-dependent FMN reductase; Region: FMN_red; pfam03358 663951001072 HMMPfam hit to PF02525, Flavodoxin_2, score 6.2e-59 663951001073 PS00017 ATP/GTP-binding site motif A (P-loop). 663951001074 Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane]; Region: NlpD; COG0739 663951001075 Peptidase family M23; Region: Peptidase_M23; pfam01551 663951001076 1 probable transmembrane helix predicted for SATW20_02130 by TMHMM2.0 at aa 7-25 663951001077 HMMPfam hit to PF01551, Peptidase_M23, score 3.4e-42 663951001078 glycerol-3-phosphate transporter ATP-binding subunit; Provisional; Region: ugpC; PRK11650 663951001079 The N-terminal ATPase domain of the maltose transporter, MalK; Region: ABC_MalK_N; cd03301 663951001080 Walker A/P-loop; other site 663951001081 ATP binding site [chemical binding]; other site 663951001082 Q-loop/lid; other site 663951001083 ABC transporter signature motif; other site 663951001084 Walker B; other site 663951001085 D-loop; other site 663951001086 H-loop/switch region; other site 663951001087 TOBE domain; Region: TOBE; pfam03459 663951001088 HMMPfam hit to PF00005, ABC_tran, score 2.7e-60 663951001089 PS00017 ATP/GTP-binding site motif A (P-loop). 663951001090 PS00211 ABC transporters family signature. 663951001091 HMMPfam hit to PF03459, TOBE, score 1.1e-09 663951001092 Maltose-binding periplasmic proteins/domains [Carbohydrate transport and metabolism]; Region: MalE; COG2182 663951001093 Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547 663951001094 HMMPfam hit to PF01547, SBP_bac_1, score 5.3e-21 663951001095 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 663951001096 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 663951001097 dimer interface [polypeptide binding]; other site 663951001098 conserved gate region; other site 663951001099 ABC-ATPase subunit interface; other site 663951001100 HMMPfam hit to PF05154, TM2, score 6e-09 663951001101 8 probable transmembrane helices predicted for SATW20_02160 by TMHMM2.0 at aa 31-53, 68-90, 122-144,192-214, 227-249, 279-301, 326-345 and 388-410 663951001102 HMMPfam hit to PF00528, BPD_transp_1, score 5.2e-19 663951001103 PS00402 Binding-protein-dependent transport systems inner membrane comp. sign. 663951001104 ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395 663951001105 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 663951001106 dimer interface [polypeptide binding]; other site 663951001107 conserved gate region; other site 663951001108 putative PBP binding loops; other site 663951001109 ABC-ATPase subunit interface; other site 663951001110 6 probable transmembrane helices predicted for SATW20_02170 by TMHMM2.0 at aa 12-34, 75-97, 109-131,141-163, 184-206 and 242-264 663951001111 HMMPfam hit to PF00528, BPD_transp_1, score 1.8e-18 663951001112 PS00402 Binding-protein-dependent transport systems inner membrane comp. sign. 663951001113 Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673 663951001114 Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408 663951001115 Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894 663951001116 HMMPfam hit to PF01408, GFO_IDH_MocA, score 5.3e-39 663951001117 HMMPfam hit to PF02894, GFO_IDH_MocA_C, score 0.015 663951001118 Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673 663951001119 Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408 663951001120 Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894 663951001121 HMMPfam hit to PF01408, GFO_IDH_MocA, score 2.2e-38 663951001122 HMMPfam hit to PF02894, GFO_IDH_MocA_C, score 1.2e-05 663951001123 Sugar phosphate isomerases/epimerases [Carbohydrate transport and metabolism]; Region: IolE; COG1082 663951001124 AP endonuclease family 2 C terminus; Region: AP_endonuc_2_N; pfam07582 663951001125 HMMPfam hit to PF01261, AP_endonuc_2, score 3.2e-43 663951001126 HMMPfam hit to PF07582, AP_endonuc_2_N, score 2.8e-19 663951001127 Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1755 663951001128 HMMPfam hit to PF04140, ICMT, score 3.2e-47 663951001129 3 probable transmembrane helices predicted for SATW20_02210 by TMHMM2.0 at aa 43-60, 65-87 and 131-153 663951001130 sugar phosphate antiporter; Reviewed; Region: uhpT; PRK09556 663951001131 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 663951001132 putative substrate translocation pore; other site 663951001133 12 probable transmembrane helices predicted for SATW20_02220 by TMHMM2.0 at aa 22-44, 64-86, 99-121,125-147, 160-180, 190-212, 252-274, 294-316, 325-344,354-376, 389-408 and 428-450 663951001134 HMMPfam hit to PF07690, MFS_1, score 6.9e-42 663951001135 PS00942 glpT family of transporters signature. 663951001136 Response regulator receiver domain; Region: Response_reg; pfam00072 663951001137 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 663951001138 active site 663951001139 phosphorylation site [posttranslational modification] 663951001140 intermolecular recognition site; other site 663951001141 dimerization interface [polypeptide binding]; other site 663951001142 Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165 663951001143 helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342 663951001144 Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165 663951001145 HMMPfam hit to PF00165, HTH_AraC, score 1.8e-05 663951001146 HMMPfam hit to PF00072, Response_reg, score 8e-28 663951001147 Predicted signal transduction protein with a C-terminal ATPase domain [Signal transduction mechanisms]; Region: COG2972 663951001148 Histidine kinase; Region: His_kinase; pfam06580 663951001149 Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075 663951001150 ATP binding site [chemical binding]; other site 663951001151 Mg2+ binding site [ion binding]; other site 663951001152 G-X-G motif; other site 663951001153 HMMPfam hit to PF02518, HATPase_c, score 4.8e-05 663951001154 HMMPfam hit to PF06580, His_kinase, score 1.3e-31 663951001155 2 probable transmembrane helices predicted for SATW20_02240 by TMHMM2.0 at aa 15-37 and 222-244 663951001156 Bacterial extracellular solute-binding protein; Region: SBP_bac_11; pfam13531 663951001157 ABC-type Fe3+ transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: AfuA; COG1840 663951001158 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 663951001159 formate acetyltransferase 1; Region: pyr_form_ly_1; TIGR01255 663951001160 Pyruvate formate lyase 1; Region: PFL1; cd01678 663951001161 coenzyme A binding site [chemical binding]; other site 663951001162 active site 663951001163 catalytic residues [active] 663951001164 glycine loop; other site 663951001165 HMMPfam hit to PF02901, PFL, score 0 663951001166 HMMPfam hit to PF01228, Gly_radical, score 5.6e-47 663951001167 PS00850 Glycine radical signature. 663951001168 pyruvate formate-lyase 1-activating enzyme; Region: PFLA; TIGR02493 663951001169 Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335 663951001170 FeS/SAM binding site; other site 663951001171 Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold; Region: Thioredoxin_like; cl00388 663951001172 PS01087 Radical activating enzymes signature. 663951001173 HMMPfam hit to PF04055, Radical_SAM, score 6.8e-27 663951001174 PS00190 Cytochrome c family heme-binding site signature. 663951001175 Membrane domain of membrane-anchored glycerophosphoryl diester phosphodiesterase [Energy production and conversion]; Region: COG4781 663951001176 Glycerophosphoryl diester phosphodiesterase [Energy production and conversion]; Region: UgpQ; COG0584 663951001177 Glycerophosphodiester phosphodiesterase domain of uncharacterized bacterial glycerophosphodiester phosphodiesterases; Region: GDPD_memb_like; cd08579 663951001178 putative active site [active] 663951001179 catalytic site [active] 663951001180 putative metal binding site [ion binding]; other site 663951001181 7 probable transmembrane helices predicted for SATW20_02290 by TMHMM2.0 at aa 21-43, 70-101, 122-144,174-196, 223-245, 255-274 and 312-334 663951001182 HMMPfam hit to PF03009, GDPD, score 6.1e-23 663951001183 Staphylococcal complement inhibitor SCIN; Region: CompInhib_SCIN; pfam11546 663951001184 Staphylococcus aureus coagulase; Region: Coagulase; pfam08764 663951001185 Staphylocoagulase repeat; Region: Staphylcoagulse; pfam04022 663951001186 Staphylocoagulase repeat; Region: Staphylcoagulse; pfam04022 663951001187 Staphylocoagulase repeat; Region: Staphylcoagulse; pfam04022 663951001188 Staphylocoagulase repeat; Region: Staphylcoagulse; pfam04022 663951001189 Staphylocoagulase repeat; Region: Staphylcoagulse; pfam04022 663951001190 Staphylocoagulase repeat; Region: Staphylcoagulse; pfam04022 663951001191 HMMPfam hit to PF08764, Coagulase, score 2.2e-202 663951001192 PS00429 Staphylocoagulase repeat signature. 663951001193 HMMPfam hit to PF04022, Staphylcoagulse, score 2.1e-14 663951001194 PS00429 Staphylocoagulase repeat signature. 663951001195 HMMPfam hit to PF04022, Staphylcoagulse, score 6.5e-15 663951001196 PS00429 Staphylocoagulase repeat signature. 663951001197 HMMPfam hit to PF04022, Staphylcoagulse, score 2e-14 663951001198 PS00429 Staphylocoagulase repeat signature. 663951001199 HMMPfam hit to PF04022, Staphylcoagulse, score 6.5e-15 663951001200 PS00429 Staphylocoagulase repeat signature. 663951001201 HMMPfam hit to PF04022, Staphylcoagulse, score 6.5e-15 663951001202 PS00429 Staphylocoagulase repeat signature. 663951001203 HMMPfam hit to PF04022, Staphylcoagulse, score 2e-13 663951001204 acetyl-CoA acetyltransferase; Provisional; Region: PRK09052 663951001205 Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751 663951001206 dimer interface [polypeptide binding]; other site 663951001207 active site 663951001208 1 probable transmembrane helix predicted for SATW20_02320 by TMHMM2.0 at aa 371-393 663951001209 HMMPfam hit to PF02803, Thiolase_C, score 1.2e-72 663951001210 PS00099 Thiolases active site. 663951001211 PS00737 Thiolases signature 2. 663951001212 HMMPfam hit to PF00108, Thiolase_N, score 2.6e-95 663951001213 PS00098 Thiolases acyl-enzyme intermediate signature. 663951001214 3-hydroxyacyl-CoA dehydrogenase [Lipid metabolism]; Region: FadB; COG1250 663951001215 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; Region: 3HCDH_N; pfam02737 663951001216 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725 663951001217 Enoyl-CoA hydratase/carnithine racemase [Lipid metabolism]; Region: CaiD; COG1024 663951001218 Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558 663951001219 substrate binding site [chemical binding]; other site 663951001220 oxyanion hole (OAH) forming residues; other site 663951001221 trimer interface [polypeptide binding]; other site 663951001222 HMMPfam hit to PF00378, ECH, score 1e-12 663951001223 PS00166 Enoyl-CoA hydratase/isomerase signature. 663951001224 HMMPfam hit to PF00725, 3HCDH, score 4.4e-29 663951001225 HMMPfam hit to PF02737, 3HCDH_N, score 5.7e-70 663951001226 Acyl-CoA dehydrogenase; Region: ACAD; cl09933 663951001227 Acyl-CoA dehydrogenases [Lipid metabolism]; Region: CaiA; COG1960 663951001228 active site 663951001229 HMMPfam hit to PF00441, Acyl-CoA_dh_1, score 3.9e-27 663951001230 HMMPfam hit to PF02770, Acyl-CoA_dh_M, score 6.2e-25 663951001231 HMMPfam hit to PF02771, Acyl-CoA_dh_N, score 1.8e-06 663951001232 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II [Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism]; Region: CaiC; COG0318 663951001233 Adenylate forming domain, Class I; Region: AFD_class_I; cl17068 663951001234 acyl-activating enzyme (AAE) consensus motif; other site 663951001235 AMP binding site [chemical binding]; other site 663951001236 active site 663951001237 CoA binding site [chemical binding]; other site 663951001238 HMMPfam hit to PF00501, AMP-binding, score 8e-119 663951001239 PS00455 Putative AMP-binding domain signature. 663951001240 Acyl CoA:acetate/3-ketoacid CoA transferase [Lipid metabolism]; Region: COG4670 663951001241 Coenzyme A transferase; Region: CoA_trans; smart00882 663951001242 Coenzyme A transferase; Region: CoA_trans; cl17247 663951001243 HMMPfam hit to PF01144, CoA_trans, score 8.5e-07 663951001244 GMP synthase - Glutamine amidotransferase domain [Nucleotide transport and metabolism]; Region: GuaA; COG0518 663951001245 Subgroup of proteins having the Type 1 glutamine amidotransferase (GATase1) domain; Region: GATase1_1; cd01741 663951001246 catalytic triad [active] 663951001247 HMMPfam hit to PF00117, GATase, score 3.9e-06 663951001248 Membrane proteinase, regulator of anti-sigma factor [Posttranslational modification, protein turnover, chaperones]; Region: prsW; COG2339 663951001249 8 probable transmembrane helices predicted for SATW20_02380 by TMHMM2.0 at aa 136-158, 163-185, 198-220,235-257, 264-286, 301-323, 344-366 and 371-390 663951001250 The substrate-binding component of an uncharacterized ABC-type nickel/dipeptide/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like_3; cd08490 663951001251 Bacterial extracellular solute-binding proteins, family 5 Middle; Region: SBP_bac_5; pfam00496 663951001252 HMMPfam hit to PF00496, SBP_bac_5, score 1.5e-66 663951001253 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 663951001254 Uncharacterized conserved protein [Function unknown]; Region: COG3189 663951001255 HMMPfam hit to PF04343, DUF488, score 2.7e-42 663951001256 2 probable transmembrane helices predicted for SATW20_02410 by TMHMM2.0 at aa 7-24 and 34-51 663951001257 bifunctional nitric oxide dioxygenase/dihydropteridine reductase 2; Provisional; Region: PRK13289 663951001258 Globins are heme proteins, which bind and transport oxygen. This family summarizes a diverse set of homologous protein domains, including: (1) tetrameric vertebrate hemoglobins, which are the major protein component of erythrocytes and transport oxygen...; Region: globin; cd01040 663951001259 heme-binding site [chemical binding]; other site 663951001260 FAD_NAD(P)H binding domain of flavohemoglobin. Flavohemoglobins have a globin domain containing a B-type heme fused with a ferredoxin reductase-like FAD/NAD-binding domain. Flavohemoglobins detoxify nitric oxide (NO) via an NO dioxygenase reaction. The...; Region: flavohem_like_fad_nad_binding; cd06184 663951001261 FAD binding pocket [chemical binding]; other site 663951001262 FAD binding motif [chemical binding]; other site 663951001263 phosphate binding motif [ion binding]; other site 663951001264 beta-alpha-beta structure motif; other site 663951001265 NAD binding pocket [chemical binding]; other site 663951001266 Heme binding pocket [chemical binding]; other site 663951001267 HMMPfam hit to PF00175, NAD_binding_1, score 4.3e-05 663951001268 HMMPfam hit to PF00970, FAD_binding_6, score 8.4e-09 663951001269 HMMPfam hit to PF00042, Globin, score 2.3e-14 663951001270 L-lactate dehydrogenase; Reviewed; Region: ldh; PRK00066 663951001271 L-2-hydroxyisocapronate dehydrogenases and some bacterial L-lactate dehydrogenases; Region: HicDH_like; cd05291 663951001272 tetramer (dimer of dimers) interface [polypeptide binding]; other site 663951001273 NAD binding site [chemical binding]; other site 663951001274 dimer interface [polypeptide binding]; other site 663951001275 substrate binding site [chemical binding]; other site 663951001276 HMMPfam hit to PF00056, Ldh_1_N, score 2.4e-75 663951001277 HMMPfam hit to PF02866, Ldh_1_C, score 5.7e-69 663951001278 PS00064 L-lactate dehydrogenase active site. 663951001279 PTS system, glucose-specific IIBC component; Region: PTS-II-BC-glcB; TIGR02002 663951001280 Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263 663951001281 PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212 663951001282 active site turn [active] 663951001283 phosphorylation site [posttranslational modification] 663951001284 HMMPfam hit to PF00367, PTS_EIIB, score 3.4e-13 663951001285 PS01035 PTS EIIB domains cysteine phosphorylation site signature. 663951001286 11 probable transmembrane helices predicted for SATW20_02440 by TMHMM2.0 at aa 15-37, 58-80, 93-115,128-150, 170-192, 199-221, 280-302, 309-327, 332-354,361-383 and 388-410 663951001287 HMMPfam hit to PF02378, PTS_EIIC, score 2.5e-115 663951001288 nuc_hydro_IU_UC_XIUA: inosine-uridine preferring, xanthosine-inosine-uridine-adenosine-preferring and, uridine-cytidine preferring nucleoside hydrolases. Nucleoside hydrolases cleave the N-glycosidic bond in nucleosides generating ribose and the...; Region: nuc_hydro_IU_UC_XIUA; cd02651 663951001289 active site 663951001290 tetramer interface [polypeptide binding]; other site 663951001291 HMMPfam hit to PF01156, IU_nuc_hydro, score 2.6e-109 663951001292 PS01247 Inosine-uridine preferring nucleoside hydrolase family signature. 663951001293 PS00018 EF-hand calcium-binding domain. 663951001294 Transcriptional antiterminator [Transcription]; Region: BglG; COG3711 663951001295 Mga helix-turn-helix domain; Region: Mga; pfam05043 663951001296 PRD domain; Region: PRD; pfam00874 663951001297 PTS_IIB_bgl_like: the PTS (phosphotransferase system) IIB domain of a family of sensory systems composed of a membrane-bound sugar-sensor (similar to BglF) and a transcription antiterminator (similar to BglG) which regulate expression of genes involved...; Region: PTS_IIB_bgl_like; cd05568 663951001298 active site 663951001299 P-loop; other site 663951001300 phosphorylation site [posttranslational modification] 663951001301 PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211 663951001302 active site 663951001303 phosphorylation site [posttranslational modification] 663951001304 Predicted helix-turn-helix motif with score 1056.000, SD 2.78 at aa 18-39, sequence IHGKELESIFGLSRRQLGYRIQ 663951001305 HMMPfam hit to PF05043, Mga, score 1.3e-05 663951001306 HMMPfam hit to PF00874, PRD, score 1e-15 663951001307 HMMPfam hit to PF00874, PRD, score 1.3e-16 663951001308 HMMPfam hit to PF00359, PTS_EIIA_2, score 6.7e-05 663951001309 PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211 663951001310 active site 663951001311 phosphorylation site [posttranslational modification] 663951001312 HMMPfam hit to PF00359, PTS_EIIA_2, score 8.1e-12 663951001313 PTS_IIB_galactitol: subunit IIB of enzyme II (EII) of the galactitol-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is a galactitol-specific permease with two cytoplasmic domains (IIA and IIB) and a...; Region: PTS_IIB_galactitol; cd05566 663951001314 active site 663951001315 P-loop; other site 663951001316 phosphorylation site [posttranslational modification] 663951001317 HMMPfam hit to PF02302, PTS_IIB, score 1.7e-25 663951001318 Phosphotransferase system, galactitol-specific IIC component [Carbohydrate transport and metabolism]; Region: GatC; COG3775 663951001319 PTS system sugar-specific permease component; Region: EIIC-GAT; cl04451 663951001320 9 probable transmembrane helices predicted for SATW20_02490 by TMHMM2.0 at aa 10-31, 38-60, 92-114,135-157, 177-199, 220-242, 303-325, 330-352 and 357-379 663951001321 HMMPfam hit to PF03611, EIIC-GAT, score 8e-212 663951001322 Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063 663951001323 Alcohol dehydrogenases of the MDR family; Region: Zn_ADH4; cd08258 663951001324 putative NAD(P) binding site [chemical binding]; other site 663951001325 catalytic Zn binding site [ion binding]; other site 663951001326 structural Zn binding site [ion binding]; other site 663951001327 HMMPfam hit to PF08240, ADH_N, score 2.2e-48 663951001328 PS00059 Zinc-containing alcohol dehydrogenases signature. 663951001329 HMMPfam hit to PF00107, ADH_zinc_N, score 6.4e-33 663951001330 1 probable transmembrane helix predicted for SATW20_02510 by TMHMM2.0 at aa 19-41 663951001331 Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063 663951001332 NAD(P)-dependent sugar dehydrogenases; Region: sugar_DH; cd08236 663951001333 putative NAD(P) binding site [chemical binding]; other site 663951001334 catalytic Zn binding site [ion binding]; other site 663951001335 HMMPfam hit to PF08240, ADH_N, score 3.9e-45 663951001336 PS00059 Zinc-containing alcohol dehydrogenases signature. 663951001337 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 663951001338 HMMPfam hit to PF00107, ADH_zinc_N, score 2.5e-32 663951001339 CDP-ME synthetase is involved in mevalonate-independent isoprenoid production; Region: CDP-ME_synthetase; cd02516 663951001340 substrate binding site; other site 663951001341 dimer interface; other site 663951001342 HMMPfam hit to PF01128, IspD, score 3e-25 663951001343 ribitol-5-phosphate dehydrogenase; Region: ribitol-5-phosphate_DH; cd08237 663951001344 Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063 663951001345 putative NAD(P) binding site [chemical binding]; other site 663951001346 putative catalytic Zn binding site [ion binding]; other site 663951001347 HMMPfam hit to PF08240, ADH_N, score 3.2e-10 663951001348 HMMPfam hit to PF00107, ADH_zinc_N, score 8.7e-08 663951001349 Putative glycosyl/glycerophosphate transferases involved in teichoic acid biosynthesis TagF/TagB/EpsJ/RodC [Cell envelope biogenesis, outer membrane]; Region: TagB; COG1887 663951001350 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase; Region: Glyphos_transf; pfam04464 663951001351 HMMPfam hit to PF04464, Glyphos_transf, score 4.4e-80 663951001352 Putative glycosyl/glycerophosphate transferases involved in teichoic acid biosynthesis TagF/TagB/EpsJ/RodC [Cell envelope biogenesis, outer membrane]; Region: TagB; COG1887 663951001353 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase; Region: Glyphos_transf; pfam04464 663951001354 HMMPfam hit to PF04464, Glyphos_transf, score 4.8e-98 663951001355 CDP-ME synthetase is involved in mevalonate-independent isoprenoid production; Region: CDP-ME_synthetase; cd02516 663951001356 substrate binding site; other site 663951001357 dimer interface; other site 663951001358 HMMPfam hit to PF01128, IspD, score 7.4e-24 663951001359 ribitol-5-phosphate dehydrogenase; Region: ribitol-5-phosphate_DH; cd08237 663951001360 Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063 663951001361 putative NAD(P) binding site [chemical binding]; other site 663951001362 putative catalytic Zn binding site [ion binding]; other site 663951001363 HMMPfam hit to PF08240, ADH_N, score 6.6e-09 663951001364 HMMPfam hit to PF00107, ADH_zinc_N, score 1.5e-08 663951001365 Putative glycosyl/glycerophosphate transferases involved in teichoic acid biosynthesis TagF/TagB/EpsJ/RodC [Cell envelope biogenesis, outer membrane]; Region: TagB; COG1887 663951001366 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase; Region: Glyphos_transf; pfam04464 663951001367 HMMPfam hit to PF04464, Glyphos_transf, score 2.7e-83 663951001368 Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463 663951001369 Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761 663951001370 active site 663951001371 HMMPfam hit to PF00535, Glycos_transf_2, score 6.8e-40 663951001372 cell wall biosynthesis protein ScdA; Provisional; Region: PRK13276 663951001373 Domain of Unknown function (DUF542); Region: ScdA_N; pfam04405 663951001374 Hemerythrin-like domain; Region: Hr-like; cd12108 663951001375 Fe binding site [ion binding]; other site 663951001376 HMMPfam hit to PF04405, ScdA_N, score 3.6e-38 663951001377 HMMPfam hit to PF01814, Hemerythrin, score 0.00012 663951001378 HMMPfam hit to PF01814, Hemerythrin, score 0.00022 663951001379 Putative regulator of cell autolysis [Signal transduction mechanisms]; Region: LytS; COG3275 663951001380 5TMR of 5TMR-LYT; Region: 5TM-5TMR_LYT; pfam07694 663951001381 Histidine kinase; Region: His_kinase; pfam06580 663951001382 Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075 663951001383 Mg2+ binding site [ion binding]; other site 663951001384 G-X-G motif; other site 663951001385 6 probable transmembrane helices predicted for SATW20_02620 by TMHMM2.0 at aa 6-28, 40-62, 88-110,123-140, 155-172 and 184-206 663951001386 HMMPfam hit to PF07694, 5TM-5TMR_LYT, score 9e-46 663951001387 PS00038 Myc-type, 'helix-loop-helix' dimerization domain signature. 663951001388 HMMPfam hit to PF01590, GAF, score 3e-05 663951001389 HMMPfam hit to PF06580, His_kinase, score 1.5e-41 663951001390 HMMPfam hit to PF02518, HATPase_c, score 2.6e-15 663951001391 two-component response regulator; Provisional; Region: PRK14084 663951001392 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 663951001393 active site 663951001394 phosphorylation site [posttranslational modification] 663951001395 intermolecular recognition site; other site 663951001396 dimerization interface [polypeptide binding]; other site 663951001397 LytTr DNA-binding domain; Region: LytTR; pfam04397 663951001398 HMMPfam hit to PF00072, Response_reg, score 9.3e-33 663951001399 HMMPfam hit to PF04397, LytTR, score 5.4e-26 663951001400 murein hydrolase regulator LrgA; Provisional; Region: PRK04125 663951001401 HMMPfam hit to PF03788, LrgA, score 2.6e-27 663951001402 4 probable transmembrane helices predicted for SATW20_02640 by TMHMM2.0 at aa 13-30, 40-62, 69-91 and 95-117 663951001403 antiholin-like protein LrgB; Provisional; Region: PRK04288 663951001404 7 probable transmembrane helices predicted for SATW20_02650 by TMHMM2.0 at aa 5-27, 34-56, 67-84, 97-116,126-148, 155-177 and 210-232 663951001405 HMMPfam hit to PF04172, LrgB, score 6e-109 663951001406 Nitric oxide reductase large subunit [Inorganic ion transport and metabolism]; Region: NorB; COG3256 663951001407 The Tellurite-resistance/Dicarboxylate Transporter (TDT) family; Region: TDT; cl04176 663951001408 14 probable transmembrane helices predicted for SATW20_02660 by TMHMM2.0 at aa 13-32, 234-256, 294-316,336-358, 371-393, 413-435, 456-478, 493-515, 528-550,555-577, 598-620, 640-659, 680-702 and 737-754 663951001409 PS00077 Heme-copper oxidase catalytic subunit,copper B binding region signature. 663951001410 Transcriptional regulators [Transcription]; Region: PhnF; COG2188 663951001411 Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377 663951001412 DNA-binding site [nucleotide binding]; DNA binding site 663951001413 The UbiC transcription regulator-associated (UTRA) domain is a conserved ligand-binding domain; Region: UTRA; smart00866 663951001414 HMMPfam hit to PF07702, UTRA, score 8e-27 663951001415 HMMPfam hit to PF00392, GntR, score 6.6e-17 663951001416 Phosphotransferase system IIB components [Carbohydrate transport and metabolism]; Region: PtsG; COG1264 663951001417 Phosphotransferase system IIA components [Carbohydrate transport and metabolism]; Region: NagE; COG2190 663951001418 HPr interaction site; other site 663951001419 glycerol kinase (GK) interaction site [polypeptide binding]; other site 663951001420 active site 663951001421 phosphorylation site [posttranslational modification] 663951001422 HMMPfam hit to PF00358, PTS_EIIA_1, score 6.3e-40 663951001423 PS00371 PTS EIIA domains phosphorylation site signature 1. 663951001424 Glycosyl hydrolase family 1; Region: Glyco_hydro_1; cl01046 663951001425 beta-galactosidase; Region: BGL; TIGR03356 663951001426 HMMPfam hit to PF00232, Glyco_hydro_1, score 4e-148 663951001427 PS00653 Glycosyl hydrolases family 1 N-terminal signature. 663951001428 PS00572 Glycosyl hydrolases family 1 active site. 663951001429 Methyltransferase domain; Region: Methyltransf_31; pfam13847 663951001430 S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440 663951001431 S-adenosylmethionine binding site [chemical binding]; other site 663951001432 HMMPfam hit to PF08241, Methyltransf_11, score 3.5e-21 663951001433 Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524 663951001434 Ribokinase catalyses the phosphorylation of ribose to ribose-5-phosphate using ATP. This reaction is the first step in the ribose metabolism. It traps ribose within the cell after uptake and also prepares the sugar for use in the synthesis of nucleotides...; Region: ribokinase; cd01174 663951001435 substrate binding site [chemical binding]; other site 663951001436 dimer interface [polypeptide binding]; other site 663951001437 ATP binding site [chemical binding]; other site 663951001438 HMMPfam hit to PF00294, PfkB, score 1.9e-70 663951001439 PS00584 pfkB family of carbohydrate kinases signature 2. 663951001440 D-ribose pyranase; Provisional; Region: PRK11797 663951001441 HMMPfam hit to PF05025, RbsD_FucU, score 6.3e-80 663951001442 Sugar transport protein; Region: Sugar_transport; pfam06800 663951001443 10 probable transmembrane helices predicted for SATW20_02730 by TMHMM2.0 at aa 2-24, 34-56, 63-80, 95-117,122-139, 154-171, 180-202, 212-234, 241-263 and 273-292 663951001444 HMMPfam hit to PF06800, Sugar_transport, score 3.9e-162 663951001445 Transcriptional regulators [Transcription]; Region: PurR; COG1609 663951001446 Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392 663951001447 DNA binding site [nucleotide binding] 663951001448 domain linker motif; other site 663951001449 Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267 663951001450 dimerization interface [polypeptide binding]; other site 663951001451 ligand binding site [chemical binding]; other site 663951001452 HMMPfam hit to PF00532, Peripla_BP_1, score 1.1e-10 663951001453 HMMPfam hit to PF00356, LacI, score 2.5e-12 663951001454 Predicted helix-turn-helix motif with score 2168.000, SD 6.57 at aa 4-25, sequence VSIKDVAREAGVSVTTVSHILN 663951001455 PS00356 Bacterial regulatory proteins, lacI family signature. 663951001456 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 663951001457 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 663951001458 14 probable transmembrane helices predicted for SATW20_02760 by TMHMM2.0 at aa 12-34, 44-66, 79-98,102-124, 137-159, 163-182, 202-221, 225-247, 268-290,296-318, 330-352, 357-379, 391-413 and 428-450 663951001459 HMMPfam hit to PF07690, MFS_1, score 7.9e-39 663951001460 PS00962 Ribosomal protein S2 signature 1. 663951001461 Linear amide C-N hydrolases, choloylglycine hydrolase family; Region: CBAH; pfam02275 663951001462 Penicillin V acylase (PVA), also known as conjugated bile salt acid hydrolase (CBAH), catalyzes the hydrolysis of penicillin V to yield 6-amino penicillanic acid (6-APA), an important key intermediate of semisynthetic penicillins. PVA has an N-terminal...; Region: Ntn_PVA; cd00542 663951001463 active site 663951001464 HMMPfam hit to PF02275, CBAH, score 7.5e-68 663951001465 Surface antigen [General function prediction only]; Region: COG3942 663951001466 Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane]; Region: NlpD; COG0739 663951001467 Peptidase family M23; Region: Peptidase_M23; pfam01551 663951001468 HMMPfam hit to PF01551, Peptidase_M23, score 1.2e-44 663951001469 ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230 663951001470 putative bacteriocin export ABC transporter, lactococcin 972 group; Region: L_ocin_972_ABC; TIGR03608 663951001471 Walker A/P-loop; other site 663951001472 ATP binding site [chemical binding]; other site 663951001473 Q-loop/lid; other site 663951001474 ABC transporter signature motif; other site 663951001475 Walker B; other site 663951001476 D-loop; other site 663951001477 H-loop/switch region; other site 663951001478 HMMPfam hit to PF00005, ABC_tran, score 3e-47 663951001479 PS00211 ABC transporters family signature. 663951001480 PS00017 ATP/GTP-binding site motif A (P-loop). 663951001481 5 probable transmembrane helices predicted for SATW20_02800 by TMHMM2.0 at aa 15-37, 185-207, 227-249,256-278 and 283-305 663951001482 6 probable transmembrane helices predicted for SATW20_02810 by TMHMM2.0 at aa 20-42, 199-221, 242-264,279-301, 313-335 and 367-384 663951001483 1 probable transmembrane helix predicted for SATW20_02820 by TMHMM2.0 at aa 7-29 663951001484 Surface antigen [General function prediction only]; Region: COG3942 663951001485 CHAP domain; Region: CHAP; pfam05257 663951001486 HMMPfam hit to PF05257, CHAP, score 1.1e-44 663951001487 Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4842 663951001488 HMMPfam hit to PF06013, WXG100, score 2.7e-36 663951001489 Predicted membrane protein [Function unknown]; Region: COG1511 663951001490 YhgE/Pip N-terminal domain; Region: pip_yhgE_Nterm; TIGR03061 663951001491 ABC-2 type transporter; Region: ABC2_membrane; pfam01061 663951001492 6 probable transmembrane helices predicted for SATW20_02850 by TMHMM2.0 at aa 5-27, 821-843, 864-886,901-923, 928-945 and 978-1000 663951001493 type VII secretion protein EssA; Region: T7SS_EssA_Firm; TIGR03927 663951001494 1 probable transmembrane helix predicted for SATW20_02860 by TMHMM2.0 at aa 115-137 663951001495 Uncharacterized small protein [Function unknown]; Region: COG5417 663951001496 HMMPfam hit to PF08817, YukD, score 7.1e-44 663951001497 Predicted membrane protein [Function unknown]; Region: COG4499 663951001498 type VII secretion protein EssB; Region: T7_EssB; TIGR03926 663951001499 1 probable transmembrane helix predicted for SATW20_02880 by TMHMM2.0 at aa 229-251 663951001500 DNA transporter; Region: FtsK_SpoIIIE_N; pfam12538 663951001501 type VII secretion protein EssC, C-terminal domain; Region: T7_EssCb_Firm; TIGR03928 663951001502 FtsK/SpoIIIE family; Region: FtsK_SpoIIIE; pfam01580 663951001503 FtsK/SpoIIIE family; Region: FtsK_SpoIIIE; pfam01580 663951001504 2 probable transmembrane helices predicted for SATW20_02890 by TMHMM2.0 at aa 230-252 and 257-279 663951001505 HMMPfam hit to PF01580, FtsK_SpoIIIE, score 4.7e-39 663951001506 PS00017 ATP/GTP-binding site motif A (P-loop). 663951001507 HMMPfam hit to PF01580, FtsK_SpoIIIE, score 1.6e-34 663951001508 Protein of unknown function (DUF3130; Region: DUF3130; cl12867 663951001509 LXG domain of WXG superfamily; Region: LXG; pfam04740 663951001510 6 probable transmembrane helices predicted for SATW20_02930 by TMHMM2.0 at aa 13-35, 45-63, 83-105,110-132, 145-167 and 177-196 663951001511 6 probable transmembrane helices predicted for SATW20_02960 by TMHMM2.0 at aa 4-22, 27-49, 59-81, 116-133,143-165 and 172-194 663951001512 PS00095 C-5 cytosine-specific DNA methylases C-terminal signature. 663951001513 2 probable transmembrane helices predicted for SATW20_02970 by TMHMM2.0 at aa 12-34 and 49-71 663951001514 Protein of unknown function, DUF600; Region: DUF600; cl04640 663951001515 HMMPfam hit to PF04634, DUF600, score 1.7e-102 663951001516 Protein of unknown function, DUF600; Region: DUF600; cl04640 663951001517 HMMPfam hit to PF04634, DUF600, score 1.6e-107 663951001518 Protein of unknown function, DUF600; Region: DUF600; cl04640 663951001519 HMMPfam hit to PF04634, DUF600, score 3.5e-97 663951001520 3 probable transmembrane helices predicted for SATW20_03010 by TMHMM2.0 at aa 12-34, 54-76 and 97-119 663951001521 1 probable transmembrane helix predicted for SATW20_03020 by TMHMM2.0 at aa 4-21 663951001522 3 probable transmembrane helices predicted for SATW20_03030 by TMHMM2.0 at aa 13-35, 57-79 and 91-113 663951001523 3 probable transmembrane helices predicted for SATW20_03040 by TMHMM2.0 at aa 20-42, 59-81 and 101-123 663951001524 CDS contains a nonsense mutation (opal) after codon 118 663951001525 HMMPfam hit to PF04634, DUF600, score 2.3e-59 663951001526 Protein of unknown function, DUF600; Region: DUF600; cl04640 663951001527 HMMPfam hit to PF04634, DUF600, score 1.4e-92 663951001528 Protein of unknown function, DUF600; Region: DUF600; cl04640 663951001529 HMMPfam hit to PF04634, DUF600, score 5.4e-91 663951001530 3 probable transmembrane helices predicted for SATW20_03090 by TMHMM2.0 at aa 7-29, 57-79 and 91-113 663951001531 Formate/nitrite family of transporters [Inorganic ion transport and metabolism]; Region: FocA; COG2116 663951001532 HMMPfam hit to PF01226, Form_Nir_trans, score 4.2e-14 663951001533 6 probable transmembrane helices predicted for SATW20_03100 by TMHMM2.0 at aa 38-60, 75-97, 117-139,165-187, 194-216 and 242-264 663951001534 Branched-chain amino acid transport protein; Region: Branch_AA_trans; pfam05525 663951001535 HMMPfam hit to PF05525, Branch_AA_trans, score 1.9e-231 663951001536 12 probable transmembrane helices predicted for SATW20_03110 by TMHMM2.0 at aa 5-27, 37-59, 72-94, 109-131,143-165, 189-211, 223-245, 275-297, 310-332, 336-358,371-393 and 408-427 663951001537 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 663951001538 5'-nucleotidase, lipoprotein e(P4) family; Region: lipo_e_P4; TIGR01533 663951001539 HMMPfam hit to PF03767, Acid_phosphat_B, score 1.1e-89 663951001540 MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704 663951001541 ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms]; Region: SalY; COG0577 663951001542 FtsX-like permease family; Region: FtsX; pfam02687 663951001543 4 probable transmembrane helices predicted for SATW20_03130 by TMHMM2.0 at aa 13-35, 230-252, 273-295 and 315-337 663951001544 HMMPfam hit to PF02687, FtsX, score 1.6e-24 663951001545 ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136 663951001546 ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255 663951001547 Walker A/P-loop; other site 663951001548 ATP binding site [chemical binding]; other site 663951001549 Q-loop/lid; other site 663951001550 ABC transporter signature motif; other site 663951001551 Walker B; other site 663951001552 D-loop; other site 663951001553 H-loop/switch region; other site 663951001554 HMMPfam hit to PF00005, ABC_tran, score 4.3e-56 663951001555 PS00017 ATP/GTP-binding site motif A (P-loop). 663951001556 PS00211 ABC transporters family signature. 663951001557 Phosphotransferase system, EIIC; Region: PTS_EIIC_2; pfam13303 663951001558 Phosphotransferase system, fructose-specific IIC component [Carbohydrate transport and metabolism]; Region: FruA; cl17425 663951001559 9 probable transmembrane helices predicted for SATW20_03150 by TMHMM2.0 at aa 4-23, 30-47, 67-86, 93-115,130-152, 172-191, 196-218, 254-276 and 302-324 663951001560 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 663951001561 Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093 663951001562 non-specific DNA binding site [nucleotide binding]; other site 663951001563 salt bridge; other site 663951001564 sequence-specific DNA binding site [nucleotide binding]; other site 663951001565 Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524 663951001566 YeiC-like sugar kinase. Found in eukaryotes and bacteria, YeiC-like kinase is part of the ribokinase/pfkB sugar kinase superfamily. Its oligomerization state is unknown at this time; Region: YeiC_kinase_like; cd01941 663951001567 substrate binding site [chemical binding]; other site 663951001568 ATP binding site [chemical binding]; other site 663951001569 HMMPfam hit to PF01047, MarR, score 1.6e-06 663951001570 Predicted helix-turn-helix motif with score 1997.000, SD 5.99 at aa 18-39, sequence ISQRELAEAIGLSRPSVANIIS 663951001571 HMMPfam hit to PF00294, PfkB, score 2e-27 663951001572 PS00583 pfkB family of carbohydrate kinases signature 1. 663951001573 PS00584 pfkB family of carbohydrate kinases signature 2. 663951001574 Indigoidine synthase A like protein; Region: Indigoidine_A; pfam04227 663951001575 HMMPfam hit to PF04227, Indigoidine_A, score 3.9e-219 663951001576 1 probable transmembrane helix predicted for SATW20_03170 by TMHMM2.0 at aa 104-126 663951001577 Nucleoside permease [Nucleotide transport and metabolism]; Region: NupC; COG1972 663951001578 Na+ dependent nucleoside transporter N-terminus; Region: Nucleos_tra2_N; pfam01773 663951001579 Na+ dependent nucleoside transporter C-terminus; Region: Nucleos_tra2_C; pfam07662 663951001580 HMMPfam hit to PF01773, Nucleos_tra2_N, score 2.3e-29 663951001581 10 probable transmembrane helices predicted for SATW20_03180 by TMHMM2.0 at aa 4-22, 34-56, 88-110,131-153, 163-185, 192-211, 264-286, 293-315, 347-369 and 382-404 663951001582 HMMPfam hit to PF07670, Gate, score 1.2e-13 663951001583 HMMPfam hit to PF07662, Nucleos_tra2_C, score 3.7e-103 663951001584 uncharacterized subgroup of the Na(+)/iodide (NIS) cotransporter subfamily; putative solute-binding domain; Region: SLC5sbd_NIS-like_u3; cd11495 663951001585 putative transporter; Provisional; Region: PRK10484 663951001586 Na binding site [ion binding]; other site 663951001587 13 probable transmembrane helices predicted for SATW20_03190 by TMHMM2.0 at aa 4-26, 46-68, 78-100,121-143, 158-180, 187-205, 230-252, 279-301, 316-338,373-395, 405-427, 432-449 and 459-481 663951001588 HMMPfam hit to PF00474, SSF, score 2.2e-13 663951001589 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 663951001590 N-acetylneuraminate lyase; Provisional; Region: PRK04147 663951001591 N-Acetylneuraminic acid aldolase, also called N-acetylneuraminate lyase (NAL); Region: NAL; cd00954 663951001592 inhibitor site; inhibition site 663951001593 active site 663951001594 dimer interface [polypeptide binding]; other site 663951001595 catalytic residue [active] 663951001596 HMMPfam hit to PF00701, DHDPS, score 2.7e-89 663951001597 Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940 663951001598 Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012 663951001599 nucleotide binding site [chemical binding]; other site 663951001600 BadF/BadG/BcrA/BcrD ATPase family; Region: BcrAD_BadFG; cl17271 663951001601 HMMPfam hit to PF00480, ROK, score 1.4e-18 663951001602 Transcriptional regulators [Transcription]; Region: RpiR; COG1737 663951001603 Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418 663951001604 RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013 663951001605 putative active site [active] 663951001606 HMMPfam hit to PF01380, SIS, score 6.5e-15 663951001607 HMMPfam hit to PF01418, HTH_6, score 1.3e-08 663951001608 Predicted helix-turn-helix motif with score 996.000,SD 2.58 at aa 35-56, sequence STINSLAHAIGTSPATMTRFSH 663951001609 N-acetylmannosamine-6-phosphate 2-epimerase; Provisional; Region: PRK01130 663951001610 N-acetylmannosamine-6-phosphate epimerase (NanE) converts N-acetylmannosamine-6-phosphate to N-acetylglucosamine-6-phosphate. This reaction is part of the pathway that allows the usage of sialic acid as a carbohydrate source. Sialic acids are a family of...; Region: NanE; cd04729 663951001611 putative active site cavity [active] 663951001612 HMMPfam hit to PF04131, NanE, score 1.1e-81 663951001613 Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3314 663951001614 Nucleoside recognition; Region: Gate; pfam07670 663951001615 12 probable transmembrane helices predicted for SATW20_03240 by TMHMM2.0 at aa 12-31, 51-73, 80-102,124-146, 167-186, 201-223, 230-252, 304-326, 331-348,352-374, 381-403 and 413-435 663951001616 HMMPfam hit to PF07670, Gate, score 3.5e-15 663951001617 CDS is disrupted by the integration of a prophage 663951001618 HMMPfam hit to PF04650, YSIRK_signal, score 3.2e-11 663951001619 PS00017 ATP/GTP-binding site motif A (P-loop). 663951001620 PS00120 Lipases, serine active site. 663951001621 prophage phiSa1(TW20) 663951001622 Site-specific recombinase XerD [DNA replication, recombination, and repair]; Region: XerD; COG4974 663951001623 Tn1545-related conjugative transposon integrases, site-specific recombinases, DNA breaking-rejoining enzymes, C-terminal catalytic domain. This CD includes bacterial (gram positive) and phage integrases, including those similar to Tn1545, Tn5252, and...; Region: INT_Tn1545_C; cd01199 663951001624 Int/Topo IB signature motif; other site 663951001625 HMMPfam hit to PF00589, Phage_integrase, score 2.7e-61 663951001626 Short C-terminal domain; Region: SHOCT; pfam09851 663951001627 Domain of unknown function (DUF955); Region: DUF955; pfam06114 663951001628 HMMPfam hit to PF06114, DUF955, score 4.4e-16 663951001629 Predicted helix-turn-helix motif with score 989.000,SD 2.56 at aa 152-173, sequence FNIEQISYKYQMSFQAIHIAVK 663951001630 PS00142 Neutral zinc metallopeptidases, zinc-binding region signature. 663951001631 Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396 663951001632 Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093 663951001633 non-specific DNA binding site [nucleotide binding]; other site 663951001634 salt bridge; other site 663951001635 sequence-specific DNA binding site [nucleotide binding]; other site 663951001636 HMMPfam hit to PF01381, HTH_3, score 1.6e-08 663951001637 Predicted helix-turn-helix motif with score 1793.000, SD 5.29 at aa 16-37, sequence MTFAELERTLGFSNGQIRRWEK 663951001638 Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093 663951001639 non-specific DNA binding site [nucleotide binding]; other site 663951001640 salt bridge; other site 663951001641 sequence-specific DNA binding site [nucleotide binding]; other site 663951001642 Predicted helix-turn-helix motif with score 1356.000, SD 3.81 at aa 19-40, sequence MTNKQLAEMLEISSAYLSDILR 663951001643 BRO family, N-terminal domain; Region: Bro-N; smart01040 663951001644 Phage antirepressor protein KilAC domain; Region: ANT; pfam03374 663951001645 HMMPfam hit to PF02498, Bro-N, score 0.0037 663951001646 Homeodomain-like domain; Region: HTH_23; pfam13384 663951001647 Predicted helix-turn-helix motif with score 2106.000, SD 6.36 at aa 26-47, sequence ATPTQIHQLFGVCRSTVYNWLK 663951001648 Protein of unknown function (DUF1108); Region: DUF1108; pfam06531 663951001649 HMMPfam hit to PF06531, DUF1108, score 1.8e-64 663951001650 Chromosome segregation ATPases [Cell division and chromosome partitioning]; Region: Smc; COG1196 663951001651 PS00017 ATP/GTP-binding site motif A (P-loop). 663951001652 Recombinational DNA repair protein (RecE pathway) [DNA replication, recombination, and repair]; Region: RecT; COG3723 663951001653 HMMPfam hit to PF03837, RecT, score 2.4e-72 663951001654 Metal-dependent hydrolases of the beta-lactamase superfamily I [General function prediction only]; Region: PhnP; COG1235 663951001655 Single-stranded DNA-binding protein [DNA replication, recombination, and repair]; Region: Ssb; COG0629 663951001656 SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496 663951001657 dimer interface [polypeptide binding]; other site 663951001658 ssDNA binding site [nucleotide binding]; other site 663951001659 tetramer (dimer of dimers) interface [polypeptide binding]; other site 663951001660 HMMPfam hit to PF00436, SSB, score 5.9e-36 663951001661 Putative primosome component and related proteins [DNA replication, recombination, and repair]; Region: DnaD; COG3935 663951001662 DnaD and phage-associated domain; Region: DnaD_dom; TIGR01446 663951001663 HMMPfam hit to PF04271, DnaD, score 3.8e-31 663951001664 Holliday junction resolvase [DNA replication, recombination, and repair]; Region: Rus; COG4570 663951001665 HMMPfam hit to PF05866, RusA, score 2e-53 663951001666 PVL ORF-50-like family; Region: PVL_ORF50; pfam07768 663951001667 HMMPfam hit to PF07768, PVL_ORF50, score 7.1e-43 663951001668 Protein of unknwon function (DUF3310); Region: DUF3310; pfam11753 663951001669 Phage Conserved Open Reading Frame 51; Region: Phage_Orf51; pfam06194 663951001670 HMMPfam hit to PF06194, Phage_Orf51, score 2e-61 663951001671 YopX protein; Region: YopX; pfam09643 663951001672 Protein of unknown function (DUF1024); Region: DUF1024; pfam06260 663951001673 HMMPfam hit to PF06260, DUF1024, score 7.3e-61 663951001674 dUTPase; Region: dUTPase_2; pfam08761 663951001675 Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) MazG-like domain found in dimeric 2-Deoxyuridine 5'-triphosphate nucleotidohydrolase and similar proteins; Region: NTP-PPase_dUTPase; cd11527 663951001676 active site 663951001677 homodimer interface [polypeptide binding]; other site 663951001678 metal binding site [ion binding]; metal-binding site 663951001679 HMMPfam hit to PF08761, dUTPase_2, score 8e-13 663951001680 Protein of unknown function (DUF1381); Region: DUF1381; pfam07129 663951001681 HMMPfam hit to PF07129, DUF1381, score 2.6e-31 663951001682 Probable gene remnant. Similar to the C-terminal region of several proteins, including Staphylococcus aureus phage phiNM4 subname: full=putative uncharacterized protein UniProt:A0EX52 (EMBL:DQ530362) (67 aa) fasta scores: E()=9.5e-15, 100.0% id in 39 aa 663951001683 Transcriptional activator RinB; Region: RinB; pfam06116 663951001684 HMMPfam hit to PF06116, RinB, score 1.2e-39 663951001685 1 probable transmembrane helix predicted for SATW20_03580 by TMHMM2.0 at aa 5-22 663951001686 1 probable transmembrane helix predicted for SATW20_03590 by TMHMM2.0 at aa 3-22 663951001687 phage transcriptional activator, RinA family; Region: phage_rinA; TIGR01636 663951001688 phage transcriptional regulator, ArpU family; Region: phage_arpU; TIGR01637 663951001689 Terminase small subunit; Region: Terminase_2; cl01513 663951001690 PS00017 ATP/GTP-binding site motif A (P-loop). 663951001691 phage terminase, large subunit, PBSX family; Region: phage_term_2; TIGR01547 663951001692 Terminase-like family; Region: Terminase_6; pfam03237 663951001693 HMMPfam hit to PF03237, Terminase_6, score 7.5e-95 663951001694 PS00017 ATP/GTP-binding site motif A (P-loop). 663951001695 Phage portal protein, SPP1 Gp6-like; Region: Phage_prot_Gp6; pfam05133 663951001696 phage portal protein, SPP1 family; Region: portal_SPP1; TIGR01538 663951001697 HMMPfam hit to PF05133, Phage_prot_Gp6, score 1.1e-276 663951001698 Phage Mu protein F like protein; Region: Phage_Mu_F; cl10072 663951001699 HMMPfam hit to PF04233, Phage_Mu_F, score 2.2e-52 663951001700 Phage minor structural protein GP20; Region: Phage_GP20; pfam06810 663951001701 HMMPfam hit to PF06810, Phage_GP20, score 3.3e-80 663951001702 Rho termination factor, N-terminal domain; Region: Rho_N; cl06505 663951001703 HMMPfam hit to PF07498, Rho_N, score 3.1e-06 663951001704 Head-Tail Connector Protein gp15 of Bacteriophage SPP1 and similar proteins; Region: gp15; cd08055 663951001705 Bacteriophage protein of unknown function (DUF646); Region: DUF646; pfam04883 663951001706 HMMPfam hit to PF07772, TP901-1_ORF40, score 5.4e-05 663951001707 PS00268 Cecropin family signature. 663951001708 Protein of unknown function (DUF3168); Region: DUF3168; pfam11367 663951001709 Phage protein; Region: DUF3647; pfam12363 663951001710 PS00017 ATP/GTP-binding site motif A (P-loop). 663951001711 PS00017 ATP/GTP-binding site motif A (P-loop). 663951001712 Phage-related protein [Function unknown]; Region: COG5412 663951001713 Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; cl00465 663951001714 7 probable transmembrane helices predicted for SATW20_03760 by TMHMM2.0 at aa 173-195, 205-227, 508-530,572-594, 607-629, 644-666 and 673-695 663951001715 HMMPfam hit to PF05017, TMP, score 0.012 663951001716 HMMPfam hit to PF05017, TMP, score 0.2 663951001717 PS00678 Trp-Asp (WD) repeats signature. 663951001718 HMMPfam hit to PF05017, TMP, score 0.16 663951001719 HMMPfam hit to PF05017, TMP, score 0.3 663951001720 HMMPfam hit to PF05017, TMP, score 0.18 663951001721 PS00678 Trp-Asp (WD) repeats signature. 663951001722 Phage tail protein; Region: Sipho_tail; pfam05709 663951001723 Prophage endopeptidase tail; Region: Prophage_tail; pfam06605 663951001724 SGNH_hydrolase, or GDSL_hydrolase, is a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely...; Region: SGNH_hydrolase; cd00229 663951001725 active site 663951001726 catalytic triad [active] 663951001727 oxyanion hole [active] 663951001728 Domain of unknown function (DUF2479); Region: DUF2479; pfam10651 663951001729 Protein of unknown function (DUF2977); Region: DUF2977; pfam11192 663951001730 phage uncharacterized protein, XkdX family; Region: phage_XkdX; TIGR01669 663951001731 Protein of unknown function (DUF2951); Region: DUF2951; pfam11166 663951001732 1 probable transmembrane helix predicted for SATW20_03830 by TMHMM2.0 at aa 76-98 663951001733 CHAP domain; Region: CHAP; pfam05257 663951001734 Beta- N-acetylglucosaminidase [Carbohydrate transport and metabolism]; Region: LytD; COG4193 663951001735 Lysozyme subfamily 2; Region: LYZ2; smart00047 663951001736 HMMPfam hit to PF05257, CHAP, score 8e-38 663951001737 HMMPfam hit to PF01832, Glucosaminidase, score 3.1e-30 663951001738 Domain of unknown function (DUF2479); Region: DUF2479; pfam10651 663951001739 Collagen triple helix repeat (20 copies); Region: Collagen; pfam01391 663951001740 Phage tail repeat like; Region: PTR; pfam12789 663951001741 HMMPfam hit to PF01391, Collagen, score 3.6e-06 663951001742 Bacteriophage holin; Region: Phage_holin_1; pfam04531 663951001743 HMMPfam hit to PF04531, Phage_holin_1, score 8.6e-53 663951001744 2 probable transmembrane helices predicted for SATW20_03870 by TMHMM2.0 at aa 13-35 and 39-61 663951001745 CHAP domain; Region: CHAP; pfam05257 663951001746 Peptidoglycan recognition proteins (PGRPs) are pattern recognition receptors that bind, and in certain cases, hydrolyze peptidoglycans (PGNs) of bacterial cell walls. PGRPs have been divided into three classes: short PGRPs (PGRP-S), that are small (20...; Region: PGRP; cd06583 663951001747 amidase catalytic site [active] 663951001748 Zn binding residues [ion binding]; other site 663951001749 substrate binding site [chemical binding]; other site 663951001750 Bacterial SH3 domain; Region: SH3_5; pfam08460 663951001751 HMMPfam hit to PF05257, CHAP, score 2e-47 663951001752 HMMPfam hit to PF01510, Amidase_2, score 1.8e-11 663951001753 HMMPfam hit to PF08460, SH3_5, score 1.1e-30 663951001754 Esterase/lipase [Lipid metabolism]; Region: Aes; COG0657 663951001755 NADH:flavin oxidoreductases, Old Yellow Enzyme family [Energy production and conversion]; Region: NemA; COG1902 663951001756 Old yellow enzyme (OYE)-related FMN binding domain, group 4. Each monomer of OYE contains FMN as a non-covalently bound cofactor, uses NADPH as a reducing agent with oxygens, quinones, and alpha,beta-unsaturated aldehydes and ketones, and can act as...; Region: OYE_like_4_FMN; cd04735 663951001757 putative active site [active] 663951001758 putative FMN binding site [chemical binding]; other site 663951001759 putative substrate binding site [chemical binding]; other site 663951001760 putative catalytic residue [active] 663951001761 HMMPfam hit to PF00724, Oxidored_FMN, score 1.7e-48 663951001762 Flavin-utilizing monoxygenases; Region: Flavin_utilizing_monoxygenases; cd00347 663951001763 luciferase family oxidoreductase, group 1; Region: oxido_grp_1; TIGR03558 663951001764 probable F420-dependent oxidoreductase, MSMEG_4141 family; Region: F420_MSMEG_4141; TIGR03620 663951001765 HMMPfam hit to PF00296, Bac_luciferase, score 1.5e-08 663951001766 Glycine cleavage H-protein. Glycine cleavage H-proteins are part of the glycine cleavage system (GCS) found in bacteria, archea and the mitochondria of eukaryotes. GCS is a multienzyme complex consisting of 4 different components (P-, H-, T- and...; Region: GCS_H; cd06848 663951001767 lipoyl attachment site [posttranslational modification]; other site 663951001768 HMMPfam hit to PF01597, GCV_H, score 2.3e-07 663951001769 Replication protein C N-terminal domain; Region: RP-C; pfam03428 663951001770 Macro domain, Unknown family 1. The macro domain is a high-affinity ADP-ribose binding module found in a variety of proteins as a stand-alone domain or in combination with other domains like in histone macroH2A and some PARPs (poly ADP-ribose polymerases)...; Region: Macro_1; cd02906 663951001771 putative ADP-ribose binding site [chemical binding]; other site 663951001772 HMMPfam hit to PF01661, A1pp, score 1.7e-55 663951001773 NAD-dependent protein deacetylases, SIR2 family [Transcription]; Region: SIR2; COG0846 663951001774 SIR2 superfamily of proteins includes silent information regulator 2 (Sir2) enzymes which catalyze NAD+-dependent protein/histone deacetylation, where the acetyl group from the lysine epsilon-amino group is transferred to the ADP-ribose moiety of NAD+; Region: SIR2; cl00195 663951001775 Lipoate-protein ligase A [Coenzyme metabolism]; Region: LplA; COG0095 663951001776 lipoyltransferase and lipoate-protein ligase; Region: lipoyltrans; TIGR00545 663951001777 Bacterial lipoate protein ligase C-terminus; Region: Lip_prot_lig_C; pfam10437 663951001778 HMMPfam hit to PF03099, BPL_LipA_LipB, score 1.2e-13 663951001779 Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451 663951001780 aldehyde reductase, extended (e) SDRs; Region: AR_SDR_e; cd05227 663951001781 NADP binding site [chemical binding]; other site 663951001782 putative substrate binding site [chemical binding]; other site 663951001783 active site 663951001784 HMMPfam hit to PF01370, Epimerase, score 3.7e-10 663951001785 PS00152 ATP synthase alpha and beta subunits signature. 663951001786 PTS system ascorbate-specific transporter subunit IIC; Reviewed; Region: ulaA; PRK09410 663951001787 10 probable transmembrane helices predicted for SATW20_03970 by TMHMM2.0 at aa 7-29, 93-112, 119-141,145-167, 224-246, 261-283, 315-337, 341-363, 370-392 and 407-440 663951001788 HMMPfam hit to PF04215, SgaT_UlaA, score 1.8e-116 663951001789 PS00017 ATP/GTP-binding site motif A (P-loop). 663951001790 PTS_IIB_ascorbate: subunit IIB of enzyme II (EII) of the L-ascorbate-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is an L-ascorbate-specific permease with two cytoplasmic subunits (IIA and IIB) and a...; Region: PTS_IIB_ascorbate; cd05563 663951001791 active site 663951001792 P-loop; other site 663951001793 phosphorylation site [posttranslational modification] 663951001794 HMMPfam hit to PF02302, PTS_IIB, score 3.2e-28 663951001795 PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211 663951001796 active site 663951001797 phosphorylation site [posttranslational modification] 663951001798 HMMPfam hit to PF00359, PTS_EIIA_2, score 6.1e-27 663951001799 Transcriptional antiterminator [Transcription]; Region: BglG; COG3711 663951001800 HTH domain; Region: HTH_11; pfam08279 663951001801 HTH domain; Region: HTH_11; pfam08279 663951001802 PRD domain; Region: PRD; pfam00874 663951001803 PRD domain; Region: PRD; pfam00874 663951001804 PTS_IIB_bgl_like: the PTS (phosphotransferase system) IIB domain of a family of sensory systems composed of a membrane-bound sugar-sensor (similar to BglF) and a transcription antiterminator (similar to BglG) which regulate expression of genes involved...; Region: PTS_IIB_bgl_like; cd05568 663951001805 active site 663951001806 P-loop; other site 663951001807 phosphorylation site [posttranslational modification] 663951001808 PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211 663951001809 active site 663951001810 phosphorylation site [posttranslational modification] 663951001811 HMMPfam hit to PF00359, PTS_EIIA_2, score 3.2e-06 663951001812 HMMPfam hit to PF02302, PTS_IIB, score 2.2e-05 663951001813 HMMPfam hit to PF00874, PRD, score 6.5e-17 663951001814 HMMPfam hit to PF00874, PRD, score 1.6e-15 663951001815 HMMPfam hit to PF08279, HTH_11, score 1.6e-07 663951001816 Predicted helix-turn-helix motif with score 1440.000, SD 4.09 at aa 105-126, sequence VSTKQLAQDVNVSRRTIADDIK 663951001817 HMMPfam hit to PF08279, HTH_11, score 2.6e-07 663951001818 Predicted helix-turn-helix motif with score 1474.000, SD 4.21 at aa 20-41, sequence IPINTIANQLGVSPRTIQYDIA 663951001819 helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347 663951001820 MarR family; Region: MarR_2; pfam12802 663951001821 HMMPfam hit to PF01047, MarR, score 9.4e-12 663951001822 Predicted helix-turn-helix motif with score 1531.000, SD 4.40 at aa 48-69, sequence LTQNDIAKALQRTGPTVSNLLR 663951001823 Na+-driven multidrug efflux pump [Defense mechanisms]; Region: NorM; COG0534 663951001824 Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Streptococcus aureus MepA; Region: MATE_MepA_like; cd13143 663951001825 12 probable transmembrane helices predicted for SATW20_04020 by TMHMM2.0 at aa 20-42, 52-74, 95-117,132-154, 167-189, 194-216, 243-265, 285-307, 319-338,353-375, 388-410 and 415-437 663951001826 HMMPfam hit to PF01554, MatE, score 1.9e-25 663951001827 PS00038 Myc-type, 'helix-loop-helix' dimerization domain signature. 663951001828 HMMPfam hit to PF01554, MatE, score 4e-11 663951001829 MepB protein; Region: MepB; cl01985 663951001830 HMMPfam hit to PF08877, MepB, score 3.6e-69 663951001831 sn-glycerol-3-phosphate transporter; Provisional; Region: glpT; PRK11273 663951001832 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 663951001833 putative substrate translocation pore; other site 663951001834 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 663951001835 12 probable transmembrane helices predicted for SATW20_04040 by TMHMM2.0 at aa 27-44, 64-86, 93-115,119-138, 159-181, 196-215, 261-280, 300-319, 331-348,358-380, 393-415 and 420-442 663951001836 HMMPfam hit to PF07690, MFS_1, score 3.1e-59 663951001837 PS00942 glpT family of transporters signature. 663951001838 N-terminal domain of Sphingobium chlorophenolicum 2,6-dichloro-p-hydroquinone 1,2-dioxygenase (PcpA), and similar proteins; Region: PcpA_N_like; cd08346 663951001839 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903 663951001840 Zn binding site [ion binding]; other site 663951001841 C-terminal domain of Sphingobium chlorophenolicum 2,6-dichloro-p-hydroquinone 1,2-dioxygenase (PcpA), and similar proteins; Region: PcpA_C_like; cd08347 663951001842 Zn binding site [ion binding]; other site 663951001843 HMMPfam hit to PF00903, Glyoxalase, score 1.2e-12 663951001844 HMMPfam hit to PF00903, Glyoxalase, score 0.01 663951001845 putative luciferase-like monooxygenase, FMN-dependent, CE1758 family; Region: LLM_CE1758_fam; TIGR04036 663951001846 Flavin-utilizing monoxygenases; Region: Flavin_utilizing_monoxygenases; cl07892 663951001847 Flavin-utilizing monoxygenases; Region: Flavin_utilizing_monoxygenases; cd00347 663951001848 HMMPfam hit to PF00296, Bac_luciferase, score 1.8e-18 663951001849 Predicted flavoprotein [General function prediction only]; Region: COG0431 663951001850 NADPH-dependent FMN reductase; Region: FMN_red; pfam03358 663951001851 HMMPfam hit to PF03358, FMN_red, score 4e-08 663951001852 Conserved hypothetical protein 698; Region: Cons_hypoth698; pfam03601 663951001853 11 probable transmembrane helices predicted for SATW20_04080 by TMHMM2.0 at aa 9-26, 31-48, 69-88, 93-115,122-144, 154-176, 183-202, 217-234, 247-269, 273-295 and 308-330 663951001854 HMMPfam hit to PF03601, Cons_hypoth698, score 2.9e-145 663951001855 PS00142 Neutral zinc metallopeptidases, zinc-binding region signature. 663951001856 Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis]; Region: RimL; COG1670 663951001857 N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182 663951001858 HMMPfam hit to PF00583, Acetyltransf_1, score 1.3e-14 663951001859 CDS contains a frameshift after codon 218 663951001860 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 663951001861 HMMPfam hit to PF04302, DUF451, score 8.3e-182 663951001862 Tat-translocated enzyme; Region: tat_substr_1; TIGR01412 663951001863 Predicted iron-dependent peroxidase [Inorganic ion transport and metabolism]; Region: COG2837 663951001864 1 probable transmembrane helix predicted for SATW20_04120 by TMHMM2.0 at aa 21-40 663951001865 HMMPfam hit to PF04261, Dyp_perox, score 1.3e-180 663951001866 High-affinity Fe2+/Pb2+ permease [Inorganic ion transport and metabolism]; Region: FTR1; COG0672 663951001867 7 probable transmembrane helices predicted for SATW20_04130 by TMHMM2.0 at aa 5-24, 355-377, 392-409,430-449, 469-491, 498-520 and 551-568 663951001868 Sec-independent protein secretion pathway component TatC [Intracellular trafficking and secretion]; Region: TatC; COG0805 663951001869 6 probable transmembrane helices predicted for SATW20_04140 by TMHMM2.0 at aa 7-28, 43-65, 85-107,135-157, 169-186 and 190-207 663951001870 HMMPfam hit to PF00902, TatC, score 6.8e-61 663951001871 twin arginine translocase protein A; Provisional; Region: tatA; PRK14861 663951001872 HMMPfam hit to PF02416, MttA_Hcf106, score 2e-18 663951001873 1 probable transmembrane helix predicted for SATW20_04150 by TMHMM2.0 at aa 5-27 663951001874 Protein of unknown function (DUF1398); Region: DUF1398; cl11576 663951001875 Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093 663951001876 non-specific DNA binding site [nucleotide binding]; other site 663951001877 salt bridge; other site 663951001878 sequence-specific DNA binding site [nucleotide binding]; other site 663951001879 HMMPfam hit to PF01381, HTH_3, score 1.3e-14 663951001880 Predicted helix-turn-helix motif with score 2314.000, SD 7.07 at aa 14-35, sequence LNQTQLAKQAGVSRQTISLIER 663951001881 Predicted helix-turn-helix motif with score 1224.000, SD 3.36 at aa 43-64, sequence LTAIKIARIFNETVETVFIIEE 663951001882 Protein of unknown function (DUF3169); Region: DUF3169; pfam11368 663951001883 6 probable transmembrane helices predicted for SATW20_04180 by TMHMM2.0 at aa 7-25, 40-62, 95-117,121-143, 185-207 and 212-231 663951001884 ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131 663951001885 ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230 663951001886 Walker A/P-loop; other site 663951001887 ATP binding site [chemical binding]; other site 663951001888 Q-loop/lid; other site 663951001889 ABC transporter signature motif; other site 663951001890 Walker B; other site 663951001891 D-loop; other site 663951001892 H-loop/switch region; other site 663951001893 HMMPfam hit to PF00005, ABC_tran, score 2.9e-38 663951001894 PS00017 ATP/GTP-binding site motif A (P-loop). 663951001895 ABC-2 family transporter protein; Region: ABC2_membrane_5; pfam13346 663951001896 5 probable transmembrane helices predicted for SATW20_04200 by TMHMM2.0 at aa 15-37, 80-102, 107-129,141-163 and 178-200 663951001897 PS00014 Endoplasmic reticulum targeting sequence. 663951001898 Predicted membrane protein [Function unknown]; Region: COG4292 663951001899 12 probable transmembrane helices predicted for SATW20_04210 by TMHMM2.0 at aa 20-39, 49-71, 84-101,106-128, 141-163, 168-190, 202-224, 229-248, 260-282,297-319, 326-344 and 349-367 663951001900 HMMPfam hit to PF06772, LtrA, score 8.5e-165 663951001901 putative acyltransferase; Provisional; Region: PRK05790 663951001902 Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751 663951001903 dimer interface [polypeptide binding]; other site 663951001904 active site 663951001905 HMMPfam hit to PF00108, Thiolase_N, score 1e-166 663951001906 PS00098 Thiolases acyl-enzyme intermediate signature. 663951001907 HMMPfam hit to PF02803, Thiolase_C, score 2.1e-70 663951001908 PS00737 Thiolases signature 2. 663951001909 PS00099 Thiolases active site. 663951001910 Kynurenine formamidase [Amino acid transport and metabolism]; Region: COG1878 663951001911 HMMPfam hit to PF04199, Cyclase, score 2.4e-85 663951001912 CIMS - Cobalamine-independent methonine synthase, or MetE, N-terminal domain_like. Many members have been characterized as 5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferases, EC:2.1.1.14, mostly from bacteria and plants. This enzyme...; Region: CIMS_N_terminal_like; cd03312 663951001913 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase; Region: met_syn_B12ind; TIGR01371 663951001914 THF binding site; other site 663951001915 CIMS - Cobalamine-independent methonine synthase, or MetE, C-terminal domain_like. Many members have been characterized as 5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferases, EC:2.1.1.14, mostly from bacteria and plants. This enzyme...; Region: CIMS_C_terminal_like; cd03311 663951001916 substrate binding site [chemical binding]; other site 663951001917 THF binding site; other site 663951001918 zinc-binding site [ion binding]; other site 663951001919 HMMPfam hit to PF01717, Meth_synt_2, score 1.6e-178 663951001920 HMMPfam hit to PF08267, Meth_synt_1, score 5e-160 663951001921 bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase protein; Reviewed; Region: PRK08645 663951001922 Methionine synthase I (cobalamin-dependent), methyltransferase domain [Amino acid transport and metabolism]; Region: MetH; COG0646 663951001923 Methylenetetrahydrofolate reductase (MTHFR). 5,10-Methylenetetrahydrofolate is reduced to 5-methyltetrahydrofolate by methylenetetrahydrofolate reductase, a cytoplasmic, NAD(P)-dependent enzyme. 5-methyltetrahydrofolate is utilized by methionine synthase...; Region: MTHFR; cd00537 663951001924 FAD binding site [chemical binding]; other site 663951001925 HMMPfam hit to PF02219, MTHFR, score 2.6e-10 663951001926 HMMPfam hit to PF02574, S-methyl_trans, score 8.4e-58 663951001927 Cystathionine beta-lyases/cystathionine gamma-synthases [Amino acid transport and metabolism]; Region: MetC; COG0626 663951001928 CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of...; Region: CGS_like; cd00614 663951001929 homodimer interface [polypeptide binding]; other site 663951001930 substrate-cofactor binding pocket; other site 663951001931 pyridoxal 5'-phosphate binding site [chemical binding]; other site 663951001932 catalytic residue [active] 663951001933 HMMPfam hit to PF01053, Cys_Met_Meta_PP, score 5.3e-162 663951001934 PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. 663951001935 cystathionine gamma-synthase; Reviewed; Region: PRK08247 663951001936 Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321 663951001937 pyridoxal 5'-phosphate binding pocket [chemical binding]; other site 663951001938 catalytic residue [active] 663951001939 HMMPfam hit to PF01053, Cys_Met_Meta_PP, score 1.9e-140 663951001940 PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. 663951001941 Stage 0 sporulation protein J (antagonist of Soj) containing ParB-like nuclease domain [Transcription]; Region: Spo0J; COG1475 663951001942 ParB-like nuclease domain; Region: ParB; smart00470 663951001943 HMMPfam hit to PF02195, ParBc, score 7.3e-37 663951001944 Predicted helix-turn-helix motif with score 1788.000, SD 5.28 at aa 133-154, sequence ITQQEVAKRLSKSRPYIANMLR 663951001945 Small-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscS; COG0668 663951001946 Mechanosensitive ion channel; Region: MS_channel; pfam00924 663951001947 3 probable transmembrane helices predicted for SATW20_04290 by TMHMM2.0 at aa 24-46, 69-91 and 101-120 663951001948 HMMPfam hit to PF00924, MS_channel, score 2.7e-44 663951001949 Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4481 663951001950 HMMPfam hit to PF06107, DUF951, score 3.9e-40 663951001951 GTP-binding protein YchF; Reviewed; Region: PRK09601 663951001952 YchF GTPase; Region: YchF; cd01900 663951001953 G1 box; other site 663951001954 GTP/Mg2+ binding site [chemical binding]; other site 663951001955 Switch I region; other site 663951001956 G2 box; other site 663951001957 Switch II region; other site 663951001958 G3 box; other site 663951001959 G4 box; other site 663951001960 G5 box; other site 663951001961 TGS_YchF_C: This subfamily represents TGS domain-containing YchF GTP-binding protein, a universally conserved GTPase whose function is unknown. The N-terminal domain of the YchF protein belongs to the Obg-like family of GTPases, and some members of the...; Region: TGS_YchF_C; cd04867 663951001962 HMMPfam hit to PF01926, MMR_HSR1, score 1.2e-38 663951001963 PS00017 ATP/GTP-binding site motif A (P-loop). 663951001964 HMMPfam hit to PF06071, DUF933, score 1.2e-62 663951001965 30S ribosomal protein S6; Reviewed; Region: rpsF; PRK00453 663951001966 HMMPfam hit to PF01250, Ribosomal_S6, score 1.9e-36 663951001967 PS01048 Ribosomal protein S6 signature. 663951001968 Single-stranded DNA-binding protein [DNA replication, recombination, and repair]; Region: Ssb; COG0629 663951001969 SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496 663951001970 dimer interface [polypeptide binding]; other site 663951001971 ssDNA binding site [nucleotide binding]; other site 663951001972 tetramer (dimer of dimers) interface [polypeptide binding]; other site 663951001973 HMMPfam hit to PF00436, SSB, score 1.4e-34 663951001974 PS00735 Single-strand binding protein family signature 1. 663951001975 30S ribosomal protein S18; Reviewed; Region: rpsR; PRK00391 663951001976 HMMPfam hit to PF01084, Ribosomal_S18, score 1.2e-34 663951001977 PS00057 Ribosomal protein S18 signature. 663951001978 Abi-like protein; Region: Abi_2; pfam07751 663951001979 HMMPfam hit to PF07751, Abi_2, score 2e-86 663951001981 HMMPfam hit to PF00589, Phage_integrase, score 7.3e-12 663951001982 Staphylococcal/Streptococcal toxin, beta-grasp domain; Region: Stap_Strp_tox_C; pfam02876 663951001983 Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG5294 663951001984 1 probable transmembrane helix predicted for SATW20_04390 by TMHMM2.0 at aa 7-24 663951001985 HMMPfam hit to PF06486, DUF1093, score 6.7e-51 663951001986 Predicted membrane protein [Function unknown]; Region: COG3212 663951001987 Peptidase propeptide and YPEB domain; Region: PepSY; pfam03413 663951001988 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 663951001989 HMMPfam hit to PF03413, PepSY, score 0.00015 663951001990 HMMPfam hit to PF03413, PepSY, score 7.6e-07 663951001991 Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cl17200 663951001992 non-specific DNA binding site [nucleotide binding]; other site 663951001993 salt bridge; other site 663951001994 sequence-specific DNA binding site [nucleotide binding]; other site 663951001995 Predicted membrane protein [Function unknown]; Region: COG2261 663951001996 3 probable transmembrane helices predicted for SATW20_04420 by TMHMM2.0 at aa 4-23, 30-52 and 56-78 663951001997 HMMPfam hit to PF04226, Transgly_assoc, score 1.7e-18 663951001998 Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067 663951001999 catalytic core [active] 663951002000 HMMPfam hit to PF00300, PGAM, score 7.3e-41 663951002001 PS00175 Phosphoglycerate mutase family phosphohistidine signature. 663951002002 4 probable transmembrane helices predicted for SATW20_04440 by TMHMM2.0 at aa 5-23, 38-60, 67-89 and 94-116 663951002003 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 663951002004 alkyl hydroperoxide reductase subunit F; Provisional; Region: PRK15317 663951002005 Alkyl hydroperoxide reductase F subunit (AhpF) N-terminal domain (NTD) family, N-terminal TRX-fold subdomain; AhpF is a homodimeric flavoenzyme which catalyzes the NADH-dependent reduction of the peroxiredoxin AhpC, which in turn catalyzes the reduction...; Region: AhpF_NTD_N; cd02974 663951002006 catalytic residue [active] 663951002007 TRX-GRX-like family, Alkyl hydroperoxide reductase F subunit (AhpF) N-terminal domain (NTD) subfamily, C-terminal TRX-fold subdomain; AhpF is a homodimeric flavoenzyme which catalyzes the NADH-dependent reduction of the peroxiredoxin AhpC, which then...; Region: AhpF_NTD_C; cd03026 663951002008 catalytic residues [active] 663951002009 NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500 663951002010 Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070 663951002011 HMMPfam hit to PF07992, Pyr_redox_2, score 1.1e-41 663951002012 HMMPfam hit to PF00070, Pyr_redox, score 4e-24 663951002013 PS00573 Pyridine nucleotide-disulphide oxidoreductases class-II active site. 663951002014 peroxiredoxin; Region: AhpC; TIGR03137 663951002015 Peroxiredoxin (PRX) family, Typical 2-Cys PRX subfamily; PRXs are thiol-specific antioxidant (TSA) proteins, which confer a protective role in cells through its peroxidase activity by reducing hydrogen peroxide, peroxynitrite, and organic hydroperoxides; Region: PRX_Typ2cys; cd03015 663951002016 dimer interface [polypeptide binding]; other site 663951002017 decamer (pentamer of dimers) interface [polypeptide binding]; other site 663951002018 catalytic triad [active] 663951002019 peroxidatic and resolving cysteines [active] 663951002020 HMMPfam hit to PF00578, AhpC-TSA, score 7.6e-42 663951002021 This family contains NADPH-dependent flavin reductase and oxygen-insensitive nitroreductase. These enzymes are homodimeric flavoproteins that contain one FMN per monomer as a cofactor. Flavin reductase catalyzes the reduction of flavin by using NADPH as...; Region: NfsA_FRP; cd02146 663951002022 dimer interface [polypeptide binding]; other site 663951002023 FMN binding site [chemical binding]; other site 663951002024 NADPH bind site [chemical binding]; other site 663951002025 HMMPfam hit to PF00881, Nitroreductase, score 5.7e-32 663951002026 Predicted Na+/dicarboxylate symporter [General function prediction only]; Region: COG1823 663951002027 Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301 663951002028 HMMPfam hit to PF00375, SDF, score 2.7e-82 663951002029 9 probable transmembrane helices predicted for SATW20_04500 by TMHMM2.0 at aa 4-21, 34-53, 68-90, 109-131,180-202, 222-244, 264-286, 368-390 and 394-416 663951002030 Predicted helix-turn-helix motif with score 1266.000, SD 3.50 at aa 1-22, sequence MLTKEFAQRVELSEKQVRKIVQ 663951002031 Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223 663951002032 active site 663951002033 HMMPfam hit to PF00156, Pribosyltran, score 5.3e-12 663951002034 xanthine permease; Region: pbuX; TIGR03173 663951002035 HMMPfam hit to PF00860, Xan_ur_permease, score 7.7e-125 663951002036 13 probable transmembrane helices predicted for SATW20_04550 by TMHMM2.0 at aa 10-29, 36-55, 59-81, 88-107,117-139, 152-171, 176-195, 215-237, 268-290, 303-325,329-351, 358-380 and 390-412 663951002037 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 663951002038 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 663951002039 PS01116 Xanthine/uracil permeases family signature. 663951002040 inosine 5'-monophosphate dehydrogenase; Reviewed; Region: PRK05567 663951002041 TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl17186 663951002042 This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in the inosine 5' monophosphate dehydrogenase (IMPDH) protein. IMPDH is an essential enzyme that catalyzes the first step unique to GTP synthesis, playing a...; Region: CBS_pair_IMPDH; cd04601 663951002043 IMPDH: The catalytic domain of the inosine monophosphate dehydrogenase. IMPDH catalyzes the NAD-dependent oxidation of inosine 5'-monophosphate (IMP) to xanthosine 5' monophosphate (XMP). It is a rate-limiting step in the de novo synthesis of...; Region: IMPDH; cd00381 663951002044 active site 663951002045 HMMPfam hit to PF00478, IMPDH, score 3.8e-246 663951002046 HMMPfam hit to PF00571, CBS, score 2.7e-30 663951002047 PS00487 IMP dehydrogenase / GMP reductase signature. 663951002048 GMP synthase; Reviewed; Region: guaA; PRK00074 663951002049 Type 1 glutamine amidotransferase (GATase1) domain found in GMP synthetase; Region: GATase1_GMP_Synthase; cd01742 663951002050 AMP/PPi binding site [chemical binding]; other site 663951002051 candidate oxyanion hole; other site 663951002052 catalytic triad [active] 663951002053 potential glutamine specificity residues [chemical binding]; other site 663951002054 The C-terminal domain of GMP synthetase. It contains two subdomains; the ATP pyrophosphatase domain which closes to the N-termial and the dimerization domain at C-terminal end. The ATP-PPase is a twisted, five-stranded parallel beta-sheet sandwiched...; Region: GMP_synthase_C; cd01997 663951002055 ATP Binding subdomain [chemical binding]; other site 663951002056 Ligand Binding sites [chemical binding]; other site 663951002057 Dimerization subdomain; other site 663951002058 HMMPfam hit to PF00117, GATase, score 1.7e-61 663951002059 HMMPfam hit to PF03054, tRNA_Me_trans, score 1.9e-11 663951002060 HMMPfam hit to PF00958, GMP_synt_C, score 5.6e-52 663951002061 Integrase [DNA replication, recombination, and repair]; Region: XerC; COG0582 663951002062 phiLC3 phage and phage-related integrases, site-specific recombinases, DNA breaking-rejoining enzymes, C-terminal catalytic domain. This CD includes various bacterial (mainly gram positive) and phage integrases, including those similar to Lactococcus...; Region: INT_phiLC3_C; cd01189 663951002063 Int/Topo IB signature motif; other site 663951002064 putative transposon/ICE Tn5801-like 663951002065 HMMPfam hit to PF00589, Phage_integrase, score 1.5e-22 663951002066 Helix-turn-helix domain; Region: HTH_16; pfam12645 663951002067 CDS contains a nonsense mutation (ochre) after codon 48 663951002068 Predicted helix-turn-helix motif with score 1636.000, SD 4.76 at aa 123-144, sequence MSDVEIAELLNLNRSTVYRHRI 663951002069 HMMPfam hit to PF08281, Sigma70_r4_2, score 3.9e-10 663951002070 Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396 663951002071 Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093 663951002072 non-specific DNA binding site [nucleotide binding]; other site 663951002073 salt bridge; other site 663951002074 sequence-specific DNA binding site [nucleotide binding]; other site 663951002075 HMMPfam hit to PF01381, HTH_3, score 1.1e-13 663951002076 Translation elongation factors (GTPases) [Translation, ribosomal structure and biogenesis]; Region: FusA; COG0480 663951002077 Tet(M)-like family includes Tet(M), Tet(O), Tet(W), and OtrA, containing tetracycline resistant proteins; Region: TetM_like; cd04168 663951002078 G1 box; other site 663951002079 putative GEF interaction site [polypeptide binding]; other site 663951002080 GTP/Mg2+ binding site [chemical binding]; other site 663951002081 Switch I region; other site 663951002082 G2 box; other site 663951002083 G3 box; other site 663951002084 Switch II region; other site 663951002085 G4 box; other site 663951002086 G5 box; other site 663951002087 Tet_II: This subfamily represents domain II of ribosomal protection proteins Tet(M) and Tet(O). This domain has homology to domain II of the elongation factors EF-G and EF-2. Tet(M) and Tet(O) catalyze the release of tetracycline (Tc) from the ribosome...; Region: Tet_II; cd03690 663951002088 EF-G_domain IV_RPP domain is a part of bacterial ribosomal protected proteins (RPP) family. RPPs such as tetracycline resistance proteins Tet(M) and Tet(O) mediate tetracycline resistance in both gram-positive and -negative species. Tetracyclines inhibit...; Region: Tet_like_IV; cd01684 663951002089 Tet_C: C-terminus of ribosomal protection proteins Tet(M) and Tet(O). This domain has homology to the C terminal domains of the elongation factors EF-G and EF-2. Tet(M) and Tet(O) catalyze the release of tetracycline (Tc) from the ribosome in a...; Region: Tet_C; cd03711 663951002090 HMMPfam hit to PF00679, EFG_C, score 1.5e-19 663951002091 HMMPfam hit to PF03764, EFG_IV, score 1.8e-31 663951002092 HMMPfam hit to PF03144, GTP_EFTU_D2, score 2.6e-08 663951002093 HMMPfam hit to PF00009, GTP_EFTU, score 2.8e-84 663951002094 PS00301 GTP-binding elongation factors signature. 663951002095 PS00017 ATP/GTP-binding site motif A (P-loop). 663951002096 CDS contains a frameshift after codon 155 663951002097 1 probable transmembrane helix predicted for SATW20_04640 by TMHMM2.0 at aa 37-54 663951002098 Lytic Transglycosylase (LT) and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL). LTs...; Region: LT_GEWL; cd00254 663951002099 N-acetyl-D-glucosamine binding site [chemical binding]; other site 663951002100 catalytic residue [active] 663951002101 Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]; Region: Spr; COG0791 663951002102 NlpC/P60 family; Region: NLPC_P60; pfam00877 663951002103 HMMPfam hit to PF00877, NLPC_P60, score 1e-44 663951002104 1 probable transmembrane helix predicted for SATW20_04650 by TMHMM2.0 at aa 5-27 663951002105 Transmembrane amino acid transporter protein; Region: Aa_trans; cl17468 663951002106 Major Facilitator Superfamily; Region: MFS_1; pfam07690 663951002107 7 probable transmembrane helices predicted for SATW20_04660 by TMHMM2.0 at aa 13-35, 144-166, 173-195,308-330, 337-356, 371-388 and 395-417 663951002108 AAA-like domain; Region: AAA_10; pfam12846 663951002109 PS00225 Crystallins beta and gamma 'Greek key' motif signature. 663951002110 PS00017 ATP/GTP-binding site motif A (P-loop). 663951002111 TcpE family; Region: TcpE; pfam12648 663951002112 2 probable transmembrane helices predicted for SATW20_04680 by TMHMM2.0 at aa 25-47 and 51-73 663951002113 Dihydrofolate reductase [Coenzyme metabolism]; Region: FolA; COG0262 663951002114 Dihydrofolate reductase (DHFR). Reduces 7,8-dihydrofolate to 5,6,7,8-tetrahydrofolate with NADPH as a cofactor. This is an essential step in the biosynthesis of deoxythymidine phosphate since 5,6,7,8-tetrahydrofolate is required to regenerate 5; Region: DHFR; cd00209 663951002115 folate binding site [chemical binding]; other site 663951002116 NADP+ binding site [chemical binding]; other site 663951002117 HMMPfam hit to PF00186, DHFR_1, score 3.4e-60 663951002118 PS00075 Dihydrofolate reductase signature. 663951002119 transposase/IS protein; Provisional; Region: PRK09183 663951002120 The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009 663951002121 Walker A motif; other site 663951002122 ATP binding site [chemical binding]; other site 663951002123 Walker B motif; other site 663951002124 arginine finger; other site 663951002125 HMMPfam hit to PF01695, IstB, score 5e-70 663951002126 PS00017 ATP/GTP-binding site motif A (P-loop). 663951002127 Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG4584 663951002128 Integrase core domain; Region: rve; pfam00665 663951002129 HMMPfam hit to PF00665, rve, score 2e-06 663951002130 Antirestriction protein (ArdA); Region: ArdA; pfam07275 663951002131 HMMPfam hit to PF07275, ArdA, score 1.3e-94 663951002132 Abortive infection C-terminus; Region: Abi_C; pfam14355 663951002133 2 probable transmembrane helices predicted for SATW20_04780 by TMHMM2.0 at aa 15-32 and 39-58 663951002134 Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093 663951002135 non-specific DNA binding site [nucleotide binding]; other site 663951002136 salt bridge; other site 663951002137 sequence-specific DNA binding site [nucleotide binding]; other site 663951002138 Replication initiation factor; Region: Rep_trans; pfam02486 663951002139 HMMPfam hit to PF02486, Rep_trans, score 8.6e-68 663951002140 HMMPfam hit to PF01381, HTH_3, score 3.1e-09 663951002141 Predicted helix-turn-helix motif with score 1065.000, SD 2.81 at aa 20-41, sequence VSQNKLAVASHITRPYLSDIET 663951002142 FtsK/SpoIIIE family; Region: FtsK_SpoIIIE; pfam01580 663951002143 ATPases associated with a variety of cellular activities; Region: AAA; smart00382 663951002144 PS00017 ATP/GTP-binding site motif A (P-loop). 663951002145 HMMPfam hit to PF01580, FtsK_SpoIIIE, score 2.5e-43 663951002146 PS00017 ATP/GTP-binding site motif A (P-loop). 663951002147 PS00227 Tubulin subunits alpha, beta, and gamma signature. 663951002148 2 probable transmembrane helices predicted for SATW20_04810 by TMHMM2.0 at aa 20-42 and 62-84 663951002149 Bacterial protein of unknown function (DUF961); Region: DUF961; pfam06125 663951002150 HMMPfam hit to PF06125, DUF961, score 1e-63 663951002151 Bacterial protein of unknown function (DUF961); Region: DUF961; pfam06125 663951002152 HMMPfam hit to PF06125, DUF961, score 4.9e-66 663951002153 Superfamily I DNA and RNA helicases [DNA replication, recombination, and repair]; Region: UvrD; COG0210 663951002154 Part of AAA domain; Region: AAA_19; pfam13245 663951002155 Family description; Region: UvrD_C_2; pfam13538 663951002156 HMMPfam hit to PF00580, UvrD-helicase, score 4.3e-12 663951002157 HMMPfam hit to PF00580, UvrD-helicase, score 3.9e-19 663951002158 PS00017 ATP/GTP-binding site motif A (P-loop). 663951002159 ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201 663951002160 AAA domain; Region: AAA_21; pfam13304 663951002161 Walker A/P-loop; other site 663951002162 ATP binding site [chemical binding]; other site 663951002163 Predicted ATP-dependent endonuclease of the OLD family [DNA replication, recombination, and repair]; Region: COG3593 663951002164 TOPRIM_OLD: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in bacterial and archaeal nucleases of the OLD (overcome lysogenization defect) family. The bacteriophage P2 OLD protein, which has DNase as well as...; Region: TOPRIM_OLD; cd01026 663951002165 putative active site [active] 663951002166 putative metal-binding site [ion binding]; other site 663951002167 HMMPfam hit to PF02463, SMC_N, score 2.5e-05 663951002168 PS00017 ATP/GTP-binding site motif A (P-loop). 663951002169 CDS contains a frameshift after codon 103. Frameshift occurs due to a 7bp insertion 663951002170 HMMPfam hit to PF00872, Transposase_mut, score 2.3e-69 663951002171 HMMPfam hit to PF00872, Transposase_mut, score 1.4e-22 663951002172 PemK-like protein; Region: PemK; pfam02452 663951002173 Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963 663951002174 Transposase; Region: HTH_Tnp_1; cl17663 663951002175 HMMPfam hit to PF01527, Transposase_8, score 7.4e-12 663951002176 Predicted membrane protein [Function unknown]; Region: COG3759 663951002177 HMMPfam hit to PF06993, DUF1304, score 1.6e-69 663951002178 3 probable transmembrane helices predicted for SATW20_04940 by TMHMM2.0 at aa 4-22, 50-72 and 82-104 663951002179 Predicted nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: COG0702 663951002180 triphenylmethane reductase (TMR)-like proteins, NMRa-like, atypical (a) SDRs; Region: TMR_SDR_a; cd05269 663951002181 NADP binding site [chemical binding]; other site 663951002182 HMMPfam hit to PF01370, Epimerase, score 2.8e-05 663951002183 Genomic island niSa-alpha 663951002184 superantigen-like protein; Reviewed; Region: PRK13037 663951002185 Domain of unknown function (DUF1954); Region: DUF1954; pfam09199 663951002186 Staphylococcal/Streptococcal toxin, beta-grasp domain; Region: Stap_Strp_tox_C; pfam02876 663951002187 HMMPfam hit to PF09199, DUF1954, score 5.8e-40 663951002188 superantigen-like protein; Reviewed; Region: PRK13041 663951002189 Domain of unknown function (DUF1954); Region: DUF1954; pfam09199 663951002190 Staphylococcal/Streptococcal toxin, beta-grasp domain; Region: Stap_Strp_tox_C; pfam02876 663951002191 HMMPfam hit to PF09199, DUF1954, score 7.4e-46 663951002192 HMMPfam hit to PF02876, Stap_Strp_tox_C, score 0.0041 663951002193 superantigen-like protein; Reviewed; Region: PRK13335 663951002194 Domain of unknown function (DUF1954); Region: DUF1954; pfam09199 663951002195 Staphylococcal/Streptococcal toxin, beta-grasp domain; Region: Stap_Strp_tox_C; pfam02876 663951002196 HMMPfam hit to PF09199, DUF1954, score 1.4e-38 663951002197 HMMPfam hit to PF02876, Stap_Strp_tox_C, score 0.041 663951002198 PS00278 Staphyloccocal enterotoxin/Streptococcal pyrogenic exotoxin signature 2. 663951002199 superantigen-like protein; Reviewed; Region: PRK13042 663951002200 Domain of unknown function (DUF1954); Region: DUF1954; pfam09199 663951002201 Staphylococcal/Streptococcal toxin, beta-grasp domain; Region: Stap_Strp_tox_C; pfam02876 663951002202 HMMPfam hit to PF09199, DUF1954, score 9.5e-45 663951002203 HMMPfam hit to PF02876, Stap_Strp_tox_C, score 0.022 663951002204 PS00278 Staphyloccocal enterotoxin/Streptococcal pyrogenic exotoxin signature 2. 663951002205 superantigen-like protein 5; Reviewed; Region: PRK13035 663951002206 Domain of unknown function (DUF1954); Region: DUF1954; pfam09199 663951002207 Staphylococcal/Streptococcal toxin, beta-grasp domain; Region: Stap_Strp_tox_C; pfam02876 663951002208 HMMPfam hit to PF09199, DUF1954, score 1.6e-43 663951002209 PS00278 Staphyloccocal enterotoxin/Streptococcal pyrogenic exotoxin signature 2. 663951002210 superantigen-like protein; Reviewed; Region: PRK13040 663951002211 Domain of unknown function (DUF1954); Region: DUF1954; pfam09199 663951002212 Staphylococcal/Streptococcal toxin, beta-grasp domain; Region: Stap_Strp_tox_C; pfam02876 663951002213 HMMPfam hit to PF09199, DUF1954, score 6.6e-43 663951002214 PS00278 Staphyloccocal enterotoxin/Streptococcal pyrogenic exotoxin signature 2. 663951002215 superantigen-like protein 7; Reviewed; Region: PRK13346 663951002216 Domain of unknown function (DUF1954); Region: DUF1954; pfam09199 663951002217 Staphylococcal/Streptococcal toxin, beta-grasp domain; Region: Stap_Strp_tox_C; pfam02876 663951002218 HMMPfam hit to PF09199, DUF1954, score 3e-43 663951002219 HMMPfam hit to PF02876, Stap_Strp_tox_C, score 8.7e-05 663951002220 PS00278 Staphyloccocal enterotoxin/Streptococcal pyrogenic exotoxin signature 2. 663951002221 superantigen-like protein; Reviewed; Region: PRK13039 663951002222 Domain of unknown function (DUF1954); Region: DUF1954; pfam09199 663951002223 Staphylococcal/Streptococcal toxin, beta-grasp domain; Region: Stap_Strp_tox_C; pfam02876 663951002224 HMMPfam hit to PF09199, DUF1954, score 2.1e-44 663951002225 HMMPfam hit to PF02876, Stap_Strp_tox_C, score 0.00021 663951002226 PS00278 Staphyloccocal enterotoxin/Streptococcal pyrogenic exotoxin signature 2. 663951002227 superantigen-like protein; Reviewed; Region: PRK13345 663951002228 Domain of unknown function (DUF1954); Region: DUF1954; pfam09199 663951002229 Staphylococcal/Streptococcal toxin, beta-grasp domain; Region: Stap_Strp_tox_C; pfam02876 663951002230 HMMPfam hit to PF09199, DUF1954, score 2.7e-44 663951002231 HMMPfam hit to PF02876, Stap_Strp_tox_C, score 0.00031 663951002232 PS00278 Staphyloccocal enterotoxin/Streptococcal pyrogenic exotoxin signature 2. 663951002233 superantigen-like protein 5; Reviewed; Region: PRK13035 663951002234 Domain of unknown function (DUF1954); Region: DUF1954; pfam09199 663951002235 Staphylococcal/Streptococcal toxin, beta-grasp domain; Region: Stap_Strp_tox_C; pfam02876 663951002236 HMMPfam hit to PF09199, DUF1954, score 1.9e-39 663951002237 HMMPfam hit to PF02876, Stap_Strp_tox_C, score 0.019 663951002238 PS00278 Staphyloccocal enterotoxin/Streptococcal pyrogenic exotoxin signature 2. 663951002239 Type I restriction-modification system methyltransferase subunit [Defense mechanisms]; Region: HsdM; COG0286 663951002240 HsdM N-terminal domain; Region: HsdM_N; pfam12161 663951002241 S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440 663951002242 S-adenosylmethionine binding site [chemical binding]; other site 663951002243 HMMPfam hit to PF02384, N6_Mtase, score 1e-161 663951002244 PS00092 N-6 Adenine-specific DNA methylases signature. 663951002245 Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420 663951002246 Restriction endonuclease S subunits [Defense mechanisms]; Region: HsdS; COG0732 663951002247 Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420 663951002248 HMMPfam hit to PF01420, Methylase_S, score 2.4e-08 663951002249 HMMPfam hit to PF01420, Methylase_S, score 4.8e-06 663951002250 superantigen-like protein; Reviewed; Region: PRK13036 663951002251 Domain of unknown function (DUF1954); Region: DUF1954; pfam09199 663951002252 Staphylococcal/Streptococcal toxin, beta-grasp domain; Region: Stap_Strp_tox_C; pfam02876 663951002253 HMMPfam hit to PF09199, DUF1954, score 1.5e-40 663951002254 HMMPfam hit to PF02876, Stap_Strp_tox_C, score 0.022 663951002255 PS00278 Staphyloccocal enterotoxin/Streptococcal pyrogenic exotoxin signature 2. 663951002256 1 probable transmembrane helix predicted for SATW20_05120 by TMHMM2.0 at aa 7-24 663951002257 Protein of unknown function, DUF576; Region: DUF576; pfam04507 663951002258 HMMPfam hit to PF04507, DUF576, score 4.7e-191 663951002259 1 probable transmembrane helix predicted for SATW20_05130 by TMHMM2.0 at aa 12-34 663951002260 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 663951002261 Protein of unknown function, DUF576; Region: DUF576; pfam04507 663951002262 HMMPfam hit to PF04507, DUF576, score 1.7e-170 663951002263 1 probable transmembrane helix predicted for SATW20_05140 by TMHMM2.0 at aa 7-24 663951002264 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 663951002265 2 probable transmembrane helices predicted for SATW20_05180 by TMHMM2.0 at aa 4-21 and 34-56 663951002266 Putative GTPases (G3E family) [General function prediction only]; Region: COG0523 663951002267 CobW/HypB/UreG, nucleotide-binding domain; Region: cobW; pfam02492 663951002268 Cobalamin synthesis protein cobW C-terminal domain; Region: CobW_C; smart00833 663951002269 HMMPfam hit to PF02492, cobW, score 1.3e-97 663951002270 PS00017 ATP/GTP-binding site motif A (P-loop). 663951002271 HMMPfam hit to PF07683, CobW_C, score 2.1e-39 663951002272 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 663951002273 NADH dehydrogenase subunit 5; Validated; Region: PRK08601 663951002274 NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361 663951002275 14 probable transmembrane helices predicted for SATW20_05210 by TMHMM2.0 at aa 4-26, 39-58, 73-95, 102-119,123-142, 155-177, 192-214, 227-249, 254-276, 301-323,343-365, 372-390, 400-422 and 435-457 663951002276 HMMPfam hit to PF00361, Oxidored_q1, score 2.8e-46 663951002277 Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3002 663951002278 Uncharacterized protein conserved in bacteria (DUF2309); Region: DUF2309; pfam10070 663951002279 Uncharacterized conserved protein (DUF2294); Region: DUF2294; pfam10057 663951002280 4 probable transmembrane helices predicted for SATW20_05240 by TMHMM2.0 at aa 20-42, 62-79, 84-106 and 111-133 663951002281 PAP2_like_2 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This subgroup, which is specific to bacteria, lacks functional characterization and may act as a membrane-associated lipid phosphatase; Region: PAP2_like_2; cd03392 663951002282 Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671 663951002283 active site 663951002284 6 probable transmembrane helices predicted for SATW20_05250 by TMHMM2.0 at aa 13-32, 74-93, 98-116,144-161, 168-190 and 195-217 663951002285 HMMPfam hit to PF01569, PAP2, score 5.3e-16 663951002286 Esterase/lipase [General function prediction only]; Region: COG1647 663951002287 Putative lysophospholipase; Region: Hydrolase_4; pfam12146 663951002288 solute carrier 6 subfamily, Fusobacterium nucleatum Tyt1-like; solute-binding domain; Region: SLC6sbd_Tyt1-Like; cd10336 663951002289 Na2 binding site [ion binding]; other site 663951002290 putative substrate binding site 1 [chemical binding]; other site 663951002291 Na binding site 1 [ion binding]; other site 663951002292 putative substrate binding site 2 [chemical binding]; other site 663951002293 HMMPfam hit to PF00209, SNF, score 1.4e-10 663951002294 11 probable transmembrane helices predicted for SATW20_05270 by TMHMM2.0 at aa 13-30, 45-67, 94-116,144-166, 179-198, 218-240, 253-275, 303-325, 344-366,381-403 and 423-445 663951002295 Cysteine synthase [Amino acid transport and metabolism]; Region: CysK; COG0031 663951002296 CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS is a unique heme-containing enzyme that catalyzes a pyridoxal 5'-phosphate (PLP)-dependent condensation of serine and homocysteine to give cystathionine; Region: CBS_like; cd01561 663951002297 dimer interface [polypeptide binding]; other site 663951002298 pyridoxal 5'-phosphate binding site [chemical binding]; other site 663951002299 catalytic residue [active] 663951002300 HMMPfam hit to PF00291, PALP, score 1e-82 663951002301 PS00901 Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. 663951002302 cystathionine beta-lyase; Provisional; Region: PRK07671 663951002303 CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of...; Region: CGS_like; cd00614 663951002304 homodimer interface [polypeptide binding]; other site 663951002305 substrate-cofactor binding pocket; other site 663951002306 pyridoxal 5'-phosphate binding site [chemical binding]; other site 663951002307 catalytic residue [active] 663951002308 HMMPfam hit to PF01053, Cys_Met_Meta_PP, score 7.2e-200 663951002309 PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. 663951002310 ABC-type metal ion transport system, ATPase component [Inorganic ion transport and metabolism]; Region: AbcC; COG1135 663951002311 ATP-binding cassette domain of methionine transporter; Region: ABC_MetN_methionine_transporter; cd03258 663951002312 Walker A/P-loop; other site 663951002313 ATP binding site [chemical binding]; other site 663951002314 Q-loop/lid; other site 663951002315 ABC transporter signature motif; other site 663951002316 Walker B; other site 663951002317 D-loop; other site 663951002318 H-loop/switch region; other site 663951002319 NIL domain; Region: NIL; pfam09383 663951002320 HMMPfam hit to PF00005, ABC_tran, score 3.8e-69 663951002321 PS00017 ATP/GTP-binding site motif A (P-loop). 663951002322 PS00211 ABC transporters family signature. 663951002323 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 663951002324 dimer interface [polypeptide binding]; other site 663951002325 conserved gate region; other site 663951002326 ABC-ATPase subunit interface; other site 663951002327 HMMPfam hit to PF00528, BPD_transp_1, score 1.4e-15 663951002328 5 probable transmembrane helices predicted for SATW20_05310 by TMHMM2.0 at aa 20-42, 62-79, 83-105,148-170 and 190-212 663951002329 PS00402 Binding-protein-dependent transport systems inner membrane comp. sign. 663951002330 Predicted helix-turn-helix motif with score 1081.000, SD 2.87 at aa 119-140, sequence EGIIEAAKAMGASPLQIIRYFL 663951002331 NLPA lipoprotein; Region: Lipoprotein_9; pfam03180 663951002332 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 663951002333 HMMPfam hit to PF03180, Lipoprotein_9, score 1.5e-118 663951002334 LysM domain; Region: LysM; pfam01476 663951002335 Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118 663951002336 Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118 663951002337 Surface antigen [General function prediction only]; Region: COG3942 663951002338 CHAP domain; Region: CHAP; pfam05257 663951002339 HMMPfam hit to PF01476, LysM, score 8.4e-18 663951002340 HMMPfam hit to PF01476, LysM, score 2.8e-18 663951002341 HMMPfam hit to PF01476, LysM, score 1.8e-18 663951002342 HMMPfam hit to PF05257, CHAP, score 6.1e-46 663951002343 1 probable transmembrane helix predicted for SATW20_05340 by TMHMM2.0 at aa 36-55 663951002344 Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly...; Region: Nudix_Hydrolase_31; cd04690 663951002345 nudix motif; other site 663951002346 HMMPfam hit to PF00293, NUDIX, score 1.2e-11 663951002347 PS00893 mutT domain signature. 663951002348 N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301 663951002349 Acetyltransferases [General function prediction only]; Region: RimI; COG0456 663951002350 Coenzyme A binding pocket [chemical binding]; other site 663951002351 HMMPfam hit to PF00583, Acetyltransf_1, score 8.2e-10 663951002352 Predicted multitransmembrane protein [Function unknown]; Region: COG5438 663951002353 HMMPfam hit to PF07907, YibE_F, score 2.9e-105 663951002354 7 probable transmembrane helices predicted for SATW20_05370 by TMHMM2.0 at aa 4-19, 24-46, 50-72, 79-101,116-138, 180-202 and 222-244 663951002355 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 663951002356 Predicted multitransmembrane protein [Function unknown]; Region: COG5438 663951002357 8 probable transmembrane helices predicted for SATW20_05380 by TMHMM2.0 at aa 13-30, 125-142, 149-168,173-195, 202-224, 246-268, 298-320 and 340-362 663951002358 HMMPfam hit to PF07907, YibE_F, score 3.3e-106 663951002359 Transcriptional regulator [Transcription]; Region: LysR; COG0583 663951002360 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 663951002361 The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466 663951002362 dimerization interface [polypeptide binding]; other site 663951002363 HMMPfam hit to PF00126, HTH_1, score 2.6e-16 663951002364 PS00044 Bacterial regulatory proteins, lysR family signature. 663951002365 Predicted helix-turn-helix motif with score 1683.000, SD 4.92 at aa 16-37, sequence EHISETALELNIAQSAISRQIT 663951002366 glutamate synthase subunit alpha; Provisional; Region: gltB; PRK11750 663951002367 Glutamine amidotransferases class-II (Gn-AT), glutamate synthase (GltS)-type. GltS is a homodimer that synthesizes L-glutamate from 2-oxoglutarate and L-glutamine, an important step in ammonia assimilation in bacteria, cyanobacteria and plants. The...; Region: GltS; cd00713 663951002368 active site 663951002369 dimer interface [polypeptide binding]; other site 663951002370 Glutamate synthase central domain; Region: Glu_syn_central; pfam04898 663951002371 Glutamate synthase (GltS) FMN-binding domain. GltS is a complex iron-sulfur flavoprotein that catalyzes the reductive synthesis of L-glutamate from 2-oxoglutarate and L-glutamine via intramolecular channelling of ammonia, a reaction in the plant, yeast...; Region: GltS_FMN; cd02808 663951002372 active site 663951002373 FMN binding site [chemical binding]; other site 663951002374 substrate binding site [chemical binding]; other site 663951002375 3Fe-4S cluster binding site [ion binding]; other site 663951002376 gltb_C. This domain is found at the C-terminus of the large subunit (gltB) of glutamate synthase (GltS). GltS encodes a complex iron-sulfur flavoprotein that catalyzes the synthesis of L-glutamate from L-glutamine and 2-oxoglutarate. It requires the...; Region: gltB_C; cd00982 663951002377 domain interface; other site 663951002378 HMMPfam hit to PF00310, GATase_2, score 2.5e-211 663951002379 HMMPfam hit to PF04898, Glu_syn_central, score 2.2e-157 663951002380 HMMPfam hit to PF01645, Glu_synthase, score 7.5e-225 663951002381 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 663951002382 HMMPfam hit to PF01493, GXGXG, score 1.4e-62 663951002383 glutamate synthase subunit beta; Reviewed; Region: gltD; PRK12810 663951002384 HMMPfam hit to PF07992, Pyr_redox_2, score 5.6e-29 663951002385 PTS system, trehalose-specific IIBC component; Region: PTS-IIBC-Tre; TIGR01992 663951002386 PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212 663951002387 active site turn [active] 663951002388 phosphorylation site [posttranslational modification] 663951002389 Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263 663951002390 HMMPfam hit to PF00367, PTS_EIIB, score 8.8e-18 663951002391 PS01035 PTS EIIB domains cysteine phosphorylation site signature. 663951002392 HMMPfam hit to PF02378, PTS_EIIC, score 2.5e-45 663951002393 9 probable transmembrane helices predicted for SATW20_05420 by TMHMM2.0 at aa 113-135, 155-174, 181-203,266-288, 301-323, 338-360, 373-395, 400-422 and 439-461 663951002394 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 663951002395 alpha,alpha-phosphotrehalase; Region: trehalose_treC; TIGR02403 663951002396 Alpha amylase catalytic domain found in Sucrose isomerases, oligo-1,6-glucosidase (also called isomaltase; sucrase-isomaltase; alpha-limit dextrinase), dextran glucosidase (also called glucan 1,6-alpha-glucosidase), and related proteins; Region: AmyAc_SI_OligoGlu_DGase; cd11333 663951002397 Ca binding site [ion binding]; other site 663951002398 active site 663951002399 catalytic site [active] 663951002400 Domain of unknown function (DUF3459); Region: DUF3459; pfam11941 663951002401 HMMPfam hit to PF00128, Alpha-amylase, score 8.7e-134 663951002402 Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377 663951002403 DNA-binding site [nucleotide binding]; DNA binding site 663951002404 trehalose operon repressor, B. subtilis-type; Region: trehalos_R_Bsub; TIGR02404 663951002405 UTRA domain; Region: UTRA; pfam07702 663951002406 HMMPfam hit to PF00392, GntR, score 2.4e-16 663951002407 HMMPfam hit to PF07702, UTRA, score 7.6e-26 663951002408 Acetyltransferases [General function prediction only]; Region: RimI; COG0456 663951002409 N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301 663951002410 Coenzyme A binding pocket [chemical binding]; other site 663951002411 HMMPfam hit to PF00583, Acetyltransf_1, score 1.1e-12 663951002412 DNA polymerase III subunits gamma and tau; Validated; Region: PRK05563 663951002413 The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009 663951002414 Walker A motif; other site 663951002415 ATP binding site [chemical binding]; other site 663951002416 Walker B motif; other site 663951002417 arginine finger; other site 663951002418 HMMPfam hit to PF00004, AAA, score 1.4e-13 663951002419 PS00017 ATP/GTP-binding site motif A (P-loop). 663951002420 PS00190 Cytochrome c family heme-binding site signature. 663951002421 PS00214 Cytosolic fatty-acid binding proteins signature. 663951002422 hypothetical protein; Validated; Region: PRK00153 663951002423 HMMPfam hit to PF02575, DUF149, score 5.8e-50 663951002424 recombination protein RecR; Reviewed; Region: recR; PRK00076 663951002425 RecR protein; Region: RecR; pfam02132 663951002426 TOPRIM_recR: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in Escherichia coli RecR. RecR participates in the RecFOR pathway of homologous recombinational repair in prokaryotes. This pathway provides a...; Region: TOPRIM_recR; cd01025 663951002427 putative active site [active] 663951002428 putative metal-binding site [ion binding]; other site 663951002429 tetramer interface [polypeptide binding]; other site 663951002430 HMMPfam hit to PF02132, RecR, score 1.7e-19 663951002431 PS01300 RecR protein signature. 663951002432 HMMPfam hit to PF01751, Toprim, score 6.4e-16 663951002433 Arginine/lysine/ornithine decarboxylases [Amino acid transport and metabolism]; Region: LdcC; COG1982 663951002434 Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321 663951002435 pyridoxal 5'-phosphate binding pocket [chemical binding]; other site 663951002436 catalytic residue [active] 663951002437 Orn/Lys/Arg decarboxylase, C-terminal domain; Region: OKR_DC_1_C; pfam03711 663951002438 HMMPfam hit to PF01276, OKR_DC_1, score 1.8e-27 663951002439 HMMPfam hit to PF03711, OKR_DC_1_C, score 3.1e-07 663951002440 thymidylate kinase; Validated; Region: tmk; PRK00698 663951002441 Thymidine monophosphate kinase (TMPK), also known as thymidylate kinase, catalyzes the phosphorylation of thymidine monophosphate (TMP) to thymidine diphosphate (TDP) utilizing ATP as its preferred phophoryl donor. TMPK represents the rate-limiting step...; Region: TMPK; cd01672 663951002442 TMP-binding site; other site 663951002443 ATP-binding site [chemical binding]; other site 663951002444 HMMPfam hit to PF02223, Thymidylate_kin, score 3.5e-63 663951002445 PS00017 ATP/GTP-binding site motif A (P-loop). 663951002446 PS01331 Thymidylate kinase signature. 663951002447 Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3870 663951002448 HMMPfam hit to PF06153, DUF970, score 1.6e-80 663951002449 DNA polymerase III subunit delta'; Validated; Region: PRK08058 663951002450 DNA polymerase III subunit delta'; Validated; Region: PRK08485 663951002451 Uncharacterized homolog of PSP1 [Function unknown]; Region: COG1774 663951002452 HMMPfam hit to PF04468, PSP1, score 7.5e-53 663951002453 Regulator of replication initiation timing [Replication, recombination, and repair]; Region: COG4467 663951002454 HMMPfam hit to PF06156, DUF972, score 9e-63 663951002455 Predicted O-methyltransferase [General function prediction only]; Region: COG4123 663951002456 S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440 663951002457 S-adenosylmethionine binding site [chemical binding]; other site 663951002458 HMMPfam hit to PF05175, MTS, score 2.7e-06 663951002459 The GIY-YIG domain of uncharacterized protein family UPF0213 related to structure-specific endonuclease SLX1; Region: GIY-YIG_UPF0213; cd10456 663951002460 GIY-YIG motif/motif A; other site 663951002461 putative active site [active] 663951002462 putative metal binding site [ion binding]; other site 663951002463 HMMPfam hit to PF01541, GIY-YIG, score 2.6e-20 663951002464 Predicted methyltransferases [General function prediction only]; Region: COG0313 663951002465 Ribosomal RNA small subunit methyltransferase I, also known as rRNA (cytidine-2'-O-)-methyltransferase RsmI; Region: RsmI; cd11648 663951002466 putative SAM binding site [chemical binding]; other site 663951002467 putative homodimer interface [polypeptide binding]; other site 663951002468 HMMPfam hit to PF00590, TP_methylase, score 1.2e-43 663951002469 PS01296 Uncharacterized protein family UPF0011 signature. 663951002470 methionyl-tRNA synthetase; Reviewed; Region: PRK12267 663951002471 catalytic core domain of methioninyl-tRNA synthetases; Region: MetRS_core; cd00814 663951002472 active site 663951002473 HIGH motif; other site 663951002474 KMSKS motif; other site 663951002475 Anticodon-binding domain of methionyl tRNA synthetases; Region: Anticodon_Ia_Met; cd07957 663951002476 tRNA binding surface [nucleotide binding]; other site 663951002477 anticodon binding site; other site 663951002478 tRNA-binding-domain-containing Escherichia coli methionyl-tRNA synthetase (EcMetRS)-like proteins. This family includes EcMetRS and Aquifex aeolicus Trbp111 (AaTrbp111). This domain has general tRNA binding properties. MetRS aminoacylates methionine...; Region: tRNA_bind_EcMetRS_like; cd02800 663951002479 dimer interface [polypeptide binding]; other site 663951002480 putative tRNA-binding site [nucleotide binding]; other site 663951002481 HMMPfam hit to PF09334, tRNA-synt_1g, score 3.7e-218 663951002482 PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 663951002483 PS00017 ATP/GTP-binding site motif A (P-loop). 663951002484 HMMPfam hit to PF01588, tRNA_bind, score 1.3e-35 663951002485 Predicted metal-dependent hydrolases with the TIM-barrel fold [General function prediction only]; Region: COG1099 663951002486 TatD like proteins; E.coli TatD is a cytoplasmic protein, shown to have magnesium dependent DNase activity; Region: TatD_DNAse; cd01310 663951002487 active site 663951002488 HMMPfam hit to PF01026, TatD_DNase, score 3.2e-122 663951002489 PS01137 Uncharacterized protein family UPF0006 signature 1. 663951002490 PS01091 Uncharacterized protein family UPF0006 signature 3. 663951002491 ribonuclease M5; Region: 5S_RNA_mat_M5; TIGR00334 663951002492 TOPRIM_ RNase M5_like: The topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain found in Ribonuclease M5: (RNase M5) and other small primase-like proteins from bacteria and archaea. RNase M5 catalyzes the maturation of 5S rRNA in low...; Region: TOPRIM_RNase_M5_like; cd01027 663951002493 putative active site [active] 663951002494 putative metal binding site [ion binding]; other site 663951002495 Domain of unknown function (DUF4093); Region: DUF4093; pfam13331 663951002496 HMMPfam hit to PF01751, Toprim, score 4.2e-06 663951002497 16S ribosomal RNA methyltransferase KsgA/Dim1 family protein; Reviewed; Region: ksgA; PRK00274 663951002498 S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440 663951002499 S-adenosylmethionine binding site [chemical binding]; other site 663951002500 HMMPfam hit to PF00398, RrnaAD, score 7.6e-76 663951002501 PS01131 Ribosomal RNA adenine dimethylases signature. 663951002502 Protein of unknown function (DUF1021); Region: DUF1021; pfam06257 663951002503 HMMPfam hit to PF06257, DUF1021, score 9.7e-48 663951002504 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Provisional; Region: ipk; PRK00128 663951002505 GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288 663951002506 GHMP kinases C terminal; Region: GHMP_kinases_C; pfam08544 663951002507 HMMPfam hit to PF00288, GHMP_kinases_N, score 2.6e-17 663951002508 HMMPfam hit to PF08544, GHMP_kinases_C, score 1.7e-06 663951002509 pur operon repressor; Provisional; Region: PRK09213 663951002510 Bacterial purine repressor, N-terminal; Region: PuR_N; pfam09182 663951002511 Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223 663951002512 active site 663951002513 HMMPfam hit to PF09182, PuR_N, score 1.3e-35 663951002514 HMMPfam hit to PF00156, Pribosyltran, score 5.9e-22 663951002515 YjgF, YER057c, and UK114 belong to a large family of proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no...; Region: YjgF_YER057c_UK114_family; cd00448 663951002516 homotrimer interaction site [polypeptide binding]; other site 663951002517 putative active site [active] 663951002518 HMMPfam hit to PF01042, Ribonuc_L-PSP, score 9.4e-60 663951002519 PS01094 Uncharacterized protein family UPF0076 signature. 663951002520 regulatory protein SpoVG; Reviewed; Region: PRK13259 663951002521 HMMPfam hit to PF04026, SpoVG, score 1.6e-65 663951002522 bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase; Provisional; Region: glmU; PRK14354 663951002523 N-terminal domain of bacterial GlmU; Region: GT2_GlmU_N_bac; cd02540 663951002524 Substrate binding site; other site 663951002525 Mg++ binding site; other site 663951002526 N-acetyl-glucosamine-1-phosphate uridyltransferase (GlmU), C-terminal left-handed beta-helix (LbH) acetyltransferase domain: GlmU is also known as UDP-N-acetylglucosamine pyrophosphorylase. It is a bifunctional bacterial enzyme that catalyzes two...; Region: LbH_GlmU_C; cd03353 663951002527 active site 663951002528 substrate binding site [chemical binding]; other site 663951002529 CoA binding site [chemical binding]; other site 663951002530 HMMPfam hit to PF00483, NTP_transferase, score 1.3e-15 663951002531 PS00622 Bacterial regulatory proteins, luxR family signature. 663951002532 HMMPfam hit to PF00132, Hexapep, score 0.021 663951002533 HMMPfam hit to PF00132, Hexapep, score 0.42 663951002534 HMMPfam hit to PF00132, Hexapep, score 2.5 663951002535 HMMPfam hit to PF00132, Hexapep, score 1.9 663951002536 HMMPfam hit to PF00132, Hexapep, score 36 663951002537 HMMPfam hit to PF00132, Hexapep, score 46 663951002538 PS00101 Hexapeptide-repeat containing-transferases signature. 663951002539 HMMPfam hit to PF00132, Hexapep, score 0.22 663951002540 ribose-phosphate pyrophosphokinase; Provisional; Region: PRK01259 663951002541 N-terminal domain of ribose phosphate pyrophosphokinase; Region: Pribosyltran_N; pfam13793 663951002542 Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223 663951002543 active site 663951002544 PS00114 Phosphoribosyl pyrophosphate synthetase signature. 663951002545 HMMPfam hit to PF00156, Pribosyltran, score 2.8e-35 663951002546 PS00103 Purine/pyrimidine phosphoribosyl transferases signature. 663951002547 50S ribosomal protein L25/general stress protein Ctc; Reviewed; Region: PRK05618 663951002548 Ribosomal L25/TL5/CTC N-terminal 5S rRNA binding domain; Region: Ribosomal_L25_TL5_CTC; cd00495 663951002549 5S rRNA interface [nucleotide binding]; other site 663951002550 CTC domain interface [polypeptide binding]; other site 663951002551 L16 interface [polypeptide binding]; other site 663951002552 HMMPfam hit to PF01386, Ribosomal_L25p, score 3.5e-28 663951002553 PS00591 Glycosyl hydrolases family 10 active site. 663951002554 Peptidyl-tRNA hydrolase (PTH) is a monomeric protein that cleaves the ester bond linking the nascent peptide and tRNA when peptidyl-tRNA is released prematurely from the ribosome. This ensures the recycling of peptidyl-tRNAs into tRNAs produced through...; Region: PTH; cd00462 663951002555 putative active site [active] 663951002556 catalytic residue [active] 663951002557 HMMPfam hit to PF01195, Pept_tRNA_hydro, score 2.3e-81 663951002558 PS01195 Peptidyl-tRNA hydrolase signature 1. 663951002559 PS01196 Peptidyl-tRNA hydrolase signature 2. 663951002560 Transcription-repair coupling factor (superfamily II helicase) [DNA replication, recombination, and repair / Transcription]; Region: Mfd; COG1197 663951002561 CarD-like/TRCF domain; Region: CarD_CdnL_TRCF; pfam02559 663951002562 DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046 663951002563 ATP binding site [chemical binding]; other site 663951002564 putative Mg++ binding site [ion binding]; other site 663951002565 Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079 663951002566 nucleotide binding region [chemical binding]; other site 663951002567 ATP-binding site [chemical binding]; other site 663951002568 This domain is found in proteins necessary for strand-specific repair in DNA such as TRCF in Escherichia coli; Region: TRCF; smart00982 663951002569 HMMPfam hit to PF02559, CarD_TRCF, score 3e-51 663951002570 HMMPfam hit to PF00270, DEAD, score 1.5e-36 663951002571 PS00017 ATP/GTP-binding site motif A (P-loop). 663951002572 HMMPfam hit to PF00271, Helicase_C, score 1.7e-22 663951002573 HMMPfam hit to PF03461, TRCF, score 8e-48 663951002574 Membrane protein involved in the export of O-antigen and teichoic acid [General function prediction only]; Region: RfbX; COG2244 663951002575 Stage V sporulation protein B, also known as Stage III sporulation protein F, and related proteins; Region: MATE_SpoVB_like; cd13124 663951002576 HMMPfam hit to PF01943, Polysacc_synt, score 2.2e-16 663951002577 14 probable transmembrane helices predicted for SATW20_05720 by TMHMM2.0 at aa 7-29, 39-61, 82-104,114-136, 157-174, 179-198, 219-238, 268-290, 311-330,340-357, 370-392, 397-419, 432-454 and 459-481 663951002578 PS00030 Eukaryotic putative RNA-binding region RNP-1 signature. 663951002579 N-terminal S-AdoMet dependent methylase domain of Bacillus subtilis YabN and related proteins; Region: YabN_N; cd11723 663951002580 putative SAM binding site [chemical binding]; other site 663951002581 putative homodimer interface [polypeptide binding]; other site 663951002582 Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) N-terminal tandem-domain of MazG proteins from Escherichia coli and bacterial homologs; Region: NTP-PPase_MazG_Nterm; cd11528 663951002583 homodimer interface [polypeptide binding]; other site 663951002584 metal binding site [ion binding]; metal-binding site 663951002585 HMMPfam hit to PF00590, TP_methylase, score 5.7e-06 663951002586 HMMPfam hit to PF03819, MazG, score 1.2e-39 663951002587 S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site; Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165 663951002588 RNA binding surface [nucleotide binding]; other site 663951002589 HMMPfam hit to PF01479, S4, score 4.7e-08 663951002590 Septum formation initiator [Cell division and chromosome partitioning]; Region: COG2919 663951002591 Septum formation initiator; Region: DivIC; pfam04977 663951002592 1 probable transmembrane helix predicted for SATW20_05750 by TMHMM2.0 at aa 34-53 663951002593 HMMPfam hit to PF04977, DivIC, score 7.4e-22 663951002594 hypothetical protein; Provisional; Region: PRK08582 663951002595 S1_RPS1_repeat_hs4: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_hs4; cd05692 663951002596 RNA binding site [nucleotide binding]; other site 663951002597 HMMPfam hit to PF00575, S1, score 1.8e-24 663951002598 tRNA(Ile)-lysidine synthase MesJ [Cell cycle control, cell division, chromosome partitioning]; Region: MesJ; COG0037 663951002599 N-terminal domain of predicted ATPase of the PP-loop faimly implicated in cell cycle control [Cell division and chromosome partitioning]. This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases...; Region: PP-ATPase; cd01992 663951002600 Ligand Binding Site [chemical binding]; other site 663951002601 TilS substrate C-terminal domain; Region: TilS_C; smart00977 663951002602 HMMPfam hit to PF01171, ATP_bind_3, score 5.9e-90 663951002603 HMMPfam hit to PF09179, DUF1946, score 1.4e-08 663951002604 Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase [Nucleotide transport and metabolism]; Region: PyrR; COG2065 663951002605 Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223 663951002606 active site 663951002607 HMMPfam hit to PF00156, Pribosyltran, score 2.2e-33 663951002608 FtsH Extracellular; Region: FtsH_ext; pfam06480 663951002609 ATP-dependent metalloprotease FtsH; Region: FtsH_fam; TIGR01241 663951002610 The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009 663951002611 Walker A motif; other site 663951002612 ATP binding site [chemical binding]; other site 663951002613 Walker B motif; other site 663951002614 arginine finger; other site 663951002615 Peptidase family M41; Region: Peptidase_M41; pfam01434 663951002616 2 probable transmembrane helices predicted for SATW20_05790 by TMHMM2.0 at aa 4-26 and 110-132 663951002617 HMMPfam hit to PF06480, FtsH_ext, score 4.5e-35 663951002618 HMMPfam hit to PF00004, AAA, score 2.9e-103 663951002619 PS00017 ATP/GTP-binding site motif A (P-loop). 663951002620 PS00674 AAA-protein family signature. 663951002621 HMMPfam hit to PF01434, Peptidase_M41, score 1.1e-124 663951002622 Hsp33-like chaperonin; Reviewed; Region: hslO; PRK00114 663951002623 Heat shock protein 33 (Hsp33): Cytosolic protein that acts as a molecular chaperone under oxidative conditions. In normal (reducing) cytosolic conditions, four conserved Cys residues are coordinated by a Zn ion. Under oxidative stress (such as heat...; Region: Hsp33; cd00498 663951002624 dimerization interface [polypeptide binding]; other site 663951002625 domain crossover interface; other site 663951002626 redox-dependent activation switch; other site 663951002627 HMMPfam hit to PF01430, HSP33, score 6.7e-174 663951002628 Cysteine synthase [Amino acid transport and metabolism]; Region: CysK; COG0031 663951002629 CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS is a unique heme-containing enzyme that catalyzes a pyridoxal 5'-phosphate (PLP)-dependent condensation of serine and homocysteine to give cystathionine; Region: CBS_like; cd01561 663951002630 dimer interface [polypeptide binding]; other site 663951002631 pyridoxal 5'-phosphate binding site [chemical binding]; other site 663951002632 catalytic residue [active] 663951002633 HMMPfam hit to PF00291, PALP, score 2.2e-127 663951002634 PS00901 Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. 663951002635 DHPS subgroup of Pterin binding enzymes. DHPS (dihydropteroate synthase), a functional homodimer, catalyzes the condensation of p-aminobenzoic acid (pABA) in the de novo biosynthesis of folate, which is an essential cofactor in both nucleic acid and...; Region: DHPS; cd00739 663951002636 dihydropteroate synthase; Region: DHPS; TIGR01496 663951002637 substrate binding pocket [chemical binding]; other site 663951002638 dimer interface [polypeptide binding]; other site 663951002639 inhibitor binding site; inhibition site 663951002640 HMMPfam hit to PF00809, Pterin_bind, score 4.2e-99 663951002641 PS00793 Dihydropteroate synthase signature 2. 663951002642 Dihydroneopterin aldolase (DHNA) and 7,8-dihydroneopterin triphosphate epimerase domain (DHNTPE); these enzymes have been designated folB and folX, respectively. Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and...; Region: DHNA_DHNTPE; cd00534 663951002643 homooctamer interface [polypeptide binding]; other site 663951002644 active site 663951002645 HMMPfam hit to PF02152, FolB, score 4.5e-41 663951002646 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK). Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and amino acids as well as formyl-tRNA. Mammalian cells are able to utilize pre-formed folates after...; Region: HPPK; cd00483 663951002647 catalytic center binding site [active] 663951002648 ATP binding site [chemical binding]; other site 663951002649 HMMPfam hit to PF01288, HPPK, score 1.6e-59 663951002650 PS00794 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase signature. 663951002651 lysyl-tRNA synthetase; Reviewed; Region: lysS; PRK00484 663951002652 LysRS_N: N-terminal, anticodon recognition domain of lysyl-tRNA synthetases (LysRS). These enzymes are homodimeric class 2b aminoacyl-tRNA synthetases (aaRSs). This domain is a beta-barrel domain (OB fold) involved in binding the tRNA anticodon stem-loop; Region: LysRS_N; cd04322 663951002653 dimer interface [polypeptide binding]; other site 663951002654 putative anticodon binding site; other site 663951002655 Lys_tRNA synthetase (LysRS) class II core domain. Class II LysRS is a dimer which attaches a lysine to the 3' OH group of ribose of the appropriate tRNA. Its assignment to class II aaRS is based upon its structure and the presence of three...; Region: LysRS_core; cd00775 663951002656 motif 1; other site 663951002657 active site 663951002658 motif 2; other site 663951002659 motif 3; other site 663951002660 HMMPfam hit to PF01336, tRNA_anti, score 6.3e-18 663951002661 HMMPfam hit to PF00152, tRNA-synt_2, score 2.8e-132 663951002662 PS00179 Aminoacyl-transfer RNA synthetases class-II signature 1. 663951002663 PS00339 Aminoacyl-transfer RNA synthetases class-II signature 2. 663951002664 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism]; Region: ARO8; COG1167 663951002665 Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377 663951002666 DNA-binding site [nucleotide binding]; DNA binding site 663951002667 Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609 663951002668 pyridoxal 5'-phosphate binding site [chemical binding]; other site 663951002669 homodimer interface [polypeptide binding]; other site 663951002670 catalytic residue [active] 663951002671 HMMPfam hit to PF00392, GntR, score 5.4e-12 663951002672 Predicted helix-turn-helix motif with score 1366.000, SD 3.84 at aa 29-50, sequence YSKRQLSKHLSISQTTVEHAYQ 663951002673 pyridoxal 5'-phosphate synthase, synthase subunit Pdx1; Region: TIGR00343 663951002674 PdxS is a subunit of the pyridoxal 5'-phosphate (PLP) synthase, an important enzyme in deoxyxylulose 5-phosphate (DXP)-independent pathway for de novo biosynthesis of PLP, present in some eubacteria, in archaea, fungi, plants, plasmodia, and some...; Region: pdxS; cd04727 663951002675 active site 663951002676 multimer interface [polypeptide binding]; other site 663951002677 HMMPfam hit to PF01680, SOR_SNZ, score 1.7e-126 663951002678 HMMPfam hit to PF00218, IGPS, score 3e-06 663951002679 Glutamine Amidotransferase (GATase_I) involved in pyridoxine biosynthesis; Region: GATase1_PB; cd01749 663951002680 predicted active site [active] 663951002681 catalytic triad [active] 663951002682 HMMPfam hit to PF01174, SNO, score 4.6e-90 663951002683 PS01236 Uncharacterized protein family UPF0030 signature. 663951002684 Nucleoside permease [Nucleotide transport and metabolism]; Region: NupC; COG1972 663951002685 Na+ dependent nucleoside transporter N-terminus; Region: Nucleos_tra2_N; pfam01773 663951002686 Nucleoside recognition; Region: Gate; pfam07670 663951002687 Na+ dependent nucleoside transporter C-terminus; Region: Nucleos_tra2_C; pfam07662 663951002688 HMMPfam hit to PF07662, Nucleos_tra2_C, score 6.5e-108 663951002689 10 probable transmembrane helices predicted for SATW20_05900 by TMHMM2.0 at aa 4-22, 31-53, 90-109,114-133, 167-189, 194-216, 251-273, 286-308, 346-368 and 381-403 663951002690 HMMPfam hit to PF07670, Gate, score 1.3e-16 663951002691 HMMPfam hit to PF01773, Nucleos_tra2_N, score 1.8e-31 663951002692 Transcriptional repressor of class III stress genes [Transcription]; Region: CtsR; COG4463 663951002693 HMMPfam hit to PF05848, CtsR, score 5.1e-106 663951002694 Predicted helix-turn-helix motif with score 1132.000, SD 3.04 at aa 26-47, sequence IQRANIAQRFDCVPSQLNYVIK 663951002695 Modulator of heat shock repressor CtsR, McsA [Signal transduction mechanisms]; Region: COG3880 663951002696 UvrB/uvrC motif; Region: UVR; pfam02151 663951002697 HMMPfam hit to PF02151, UVR, score 9.8e-05 663951002698 Arginine kinase [Amino acid transport and metabolism]; Region: COG3869 663951002699 Phosphagen (guanidino) kinases found in bacteria; Region: bacterial_phosphagen_kinase; cd07930 663951002700 ADP binding site [chemical binding]; other site 663951002701 phosphagen binding site; other site 663951002702 substrate specificity loop; other site 663951002703 HMMPfam hit to PF00217, ATP-gua_Ptrans, score 8.6e-22 663951002704 PS00112 ATP:guanido phosphotransferases active site. 663951002705 ATP-binding subunits of Clp protease and DnaK/DnaJ chaperones [Posttranslational modification, protein turnover, chaperones]; Region: clpA; COG0542 663951002706 Clp amino terminal domain; Region: Clp_N; pfam02861 663951002707 Clp amino terminal domain; Region: Clp_N; pfam02861 663951002708 The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009 663951002709 Walker A motif; other site 663951002710 ATP binding site [chemical binding]; other site 663951002711 Walker B motif; other site 663951002712 arginine finger; other site 663951002713 UvrB/uvrC motif; Region: UVR; pfam02151 663951002714 The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009 663951002715 Walker A motif; other site 663951002716 ATP binding site [chemical binding]; other site 663951002717 Walker B motif; other site 663951002718 C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431 663951002719 HMMPfam hit to PF02861, Clp_N, score 5.4e-21 663951002720 HMMPfam hit to PF02861, Clp_N, score 1.8e-17 663951002721 HMMPfam hit to PF00004, AAA, score 9.6e-16 663951002722 PS00017 ATP/GTP-binding site motif A (P-loop). 663951002723 PS00870 Chaperonins clpA/B signature 1. 663951002724 HMMPfam hit to PF02151, UVR, score 2.9e-07 663951002725 HMMPfam hit to PF07724, AAA_2, score 1.6e-111 663951002726 PS00017 ATP/GTP-binding site motif A (P-loop). 663951002727 PS00871 Chaperonins clpA/B signature 2. 663951002728 DNA repair protein RadA; Provisional; Region: PRK11823 663951002729 Sms (bacterial radA) DNA repair protein. This protein is not related to archael radA any more than is to other RecA-like NTPases. Sms has a role in recombination and recombinational repair and is responsible for the stabilization or processing of...; Region: Sms; cd01121 663951002730 Walker A motif/ATP binding site; other site 663951002731 ATP binding site [chemical binding]; other site 663951002732 Walker B motif; other site 663951002733 Subunit ChlI of Mg-chelatase; Region: ChlI; pfam13541 663951002734 PS00017 ATP/GTP-binding site motif A (P-loop). 663951002735 Integral membrane protein (PIN domain superfamily) [General function prediction only]; Region: COG4956 663951002736 PIN domain of Thermus Thermophilus Hb8, uncharacterized Bacillus subtilis YacL, and other bacterial homologs; Region: PIN_YacL; cd09877 663951002737 putative active site [active] 663951002738 4 probable transmembrane helices predicted for SATW20_05960 by TMHMM2.0 at aa 7-29, 44-61, 82-104 and 114-133 663951002739 HMMPfam hit to PF01850, PIN, score 3.9e-14 663951002740 glutamyl-tRNA synthetase; Reviewed; Region: gltX; PRK01406 663951002741 catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808 663951002742 active site 663951002743 HIGH motif; other site 663951002744 catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808 663951002745 active site 663951002746 KMSKS motif; other site 663951002747 HMMPfam hit to PF00749, tRNA-synt_1c, score 6.4e-189 663951002748 PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 663951002749 Serine acetyltransferase [Amino acid transport and metabolism]; Region: CysE; COG1045 663951002750 Serine acetyltransferase (SAT): SAT catalyzes the CoA-dependent acetylation of the side chain hydroxyl group of L-serine to form O-acetylserine, as the first step of a two-step biosynthetic pathway in bacteria and plants leading to the formation of...; Region: LbH_SAT; cd03354 663951002751 trimer interface [polypeptide binding]; other site 663951002752 active site 663951002753 substrate binding site [chemical binding]; other site 663951002754 CoA binding site [chemical binding]; other site 663951002755 HMMPfam hit to PF00132, Hexapep, score 23 663951002756 HMMPfam hit to PF00132, Hexapep, score 0.002 663951002757 HMMPfam hit to PF00132, Hexapep, score 62 663951002758 HMMPfam hit to PF00132, Hexapep, score 10 663951002759 cysteinyl-tRNA synthetase; Validated; Region: cysS; PRK00260 663951002760 catalytic core domain of cysteinyl tRNA synthetase; Region: CysRS_core; cd00672 663951002761 active site 663951002762 HIGH motif; other site 663951002763 catalytic core domain of cysteinyl tRNA synthetase; Region: CysRS_core; cd00672 663951002764 KMSKS motif; other site 663951002765 Anticodon-binding domain of class Ia aminoacyl tRNA synthetases and similar domains; Region: Anticodon_Ia_like; cl12020 663951002766 tRNA binding surface [nucleotide binding]; other site 663951002767 anticodon binding site; other site 663951002768 HMMPfam hit to PF01406, tRNA-synt_1e, score 1.5e-187 663951002769 HMMPfam hit to PF09190, DALR_2, score 1.3e-20 663951002770 Ribonuclease III family protein [Replication, recombination, and repair]; Region: COG1939 663951002771 active site 663951002772 dimerization interface [polypeptide binding]; other site 663951002773 metal binding site [ion binding]; metal-binding site 663951002774 HMMPfam hit to PF00636, Ribonuclease_3, score 5.5e-12 663951002775 rRNA methylases [Translation, ribosomal structure and biogenesis]; Region: SpoU; COG0566 663951002776 RNA 2'-O ribose methyltransferase substrate binding; Region: SpoU_sub_bind; pfam08032 663951002777 SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588 663951002778 HMMPfam hit to PF08032, SpoU_sub_bind, score 6.1e-24 663951002779 HMMPfam hit to PF00588, SpoU_methylase, score 9.6e-60 663951002780 Predicted RNA-binding protein containing a PIN domain [General function prediction only]; Region: COG3688 663951002781 HMMPfam hit to PF05991, DUF901, score 2.4e-93 663951002782 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog [Transcription]; Region: RpoE; COG1595 663951002783 Sigma-70 region 2; Region: Sigma70_r2; pfam04542 663951002784 C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cl17315 663951002785 DNA binding residues [nucleotide binding] 663951002786 HMMPfam hit to PF04542, Sigma70_r2, score 1.4e-11 663951002787 Predicted helix-turn-helix motif with score 1274.000, SD 3.53 at aa 155-176, sequence YKPREIAQLMHVKEKVIYNAIQ 663951002788 50S ribosomal protein L33; Validated; Region: rpmG; PRK00504 663951002789 HMMPfam hit to PF00471, Ribosomal_L33, score 3.9e-11 663951002790 preprotein translocase subunit SecE; Reviewed; Region: secE; PRK07597 663951002791 HMMPfam hit to PF00584, SecE, score 1.8e-14 663951002792 PS01067 Protein secE/sec61-gamma signature. 663951002793 1 probable transmembrane helix predicted for SATW20_06050 by TMHMM2.0 at aa 31-53 663951002794 transcription antitermination protein NusG; Validated; Region: nusG; PRK05609 663951002795 Bacterial N-Utilization Substance G (NusG) N-terminal (NGN) domain, subgroup 1; Region: NGN_Bact_1; cd09891 663951002796 putative homodimer interface [polypeptide binding]; other site 663951002797 NusG contains an NGN domain at its N-terminus and KOW motif at its C-terminus; Region: KOW_NusG; cd06091 663951002798 heterodimer interface [polypeptide binding]; other site 663951002799 homodimer interface [polypeptide binding]; other site 663951002800 HMMPfam hit to PF02357, NusG, score 4.4e-54 663951002801 HMMPfam hit to PF00467, KOW, score 3.1e-10 663951002802 PS01014 Transcription termination factor nusG signature. 663951002803 50S ribosomal protein L11; Validated; Region: rplK; PRK00140 663951002804 Ribosomal protein L11. Ribosomal protein L11, together with proteins L10 and L7/L12, and 23S rRNA, form the L7/L12 stalk on the surface of the large subunit of the ribosome. The homologous eukaryotic cytoplasmic protein is also called 60S ribosomal...; Region: Ribosomal_L11; cd00349 663951002805 23S rRNA interface [nucleotide binding]; other site 663951002806 L7/L12 interface [polypeptide binding]; other site 663951002807 putative thiostrepton binding site; other site 663951002808 L25 interface [polypeptide binding]; other site 663951002809 HMMPfam hit to PF03946, Ribosomal_L11_N, score 2.6e-37 663951002810 HMMPfam hit to PF00298, Ribosomal_L11, score 1.5e-38 663951002811 PS00359 Ribosomal protein L11 signature. 663951002812 Ribosomal protein L1. The L1 protein, located near the E-site of the ribosome, forms part of the L1 stalk along with 23S rRNA. In bacteria and archaea, L1 functions both as a ribosomal protein that binds rRNA, and as a translation repressor that binds...; Region: Ribosomal_L1; cd00403 663951002813 mRNA/rRNA interface [nucleotide binding]; other site 663951002814 HMMPfam hit to PF00687, Ribosomal_L1, score 2.6e-134 663951002815 PS01199 Ribosomal protein L1 signature. 663951002816 Ribosomal protein L10 family, L10 subfamily; composed of bacterial 50S ribosomal protein and eukaryotic mitochondrial 39S ribosomal protein, L10. L10 occupies the L7/L12 stalk of the ribosome. The N-terminal domain (NTD) of L10 interacts with L11 protein...; Region: Ribosomal_L10; cd05797 663951002817 23S rRNA interface [nucleotide binding]; other site 663951002818 Interface with L7/L12 ribosomal proteins [polypeptide binding]; other site 663951002819 HMMPfam hit to PF00466, Ribosomal_L10, score 1.3e-35 663951002820 PS01109 Ribosomal protein L10 signature. 663951002821 Ribosomal protein L7/L12. Ribosomal protein L7/L12 refers to the large ribosomal subunit proteins L7 and L12, which are identical except that L7 is acetylated at the N terminus. It is a component of the L7/L12 stalk, which is located at the surface of...; Region: Ribosomal_L7_L12; cd00387 663951002822 peripheral dimer interface [polypeptide binding]; other site 663951002823 core dimer interface [polypeptide binding]; other site 663951002824 L10 interface [polypeptide binding]; other site 663951002825 L11 interface [polypeptide binding]; other site 663951002826 putative EF-Tu interaction site [polypeptide binding]; other site 663951002827 putative EF-G interaction site [polypeptide binding]; other site 663951002828 HMMPfam hit to PF00542, Ribosomal_L12, score 1.4e-37 663951002829 Methyltransferase domain; Region: Methyltransf_31; pfam13847 663951002830 S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440 663951002831 S-adenosylmethionine binding site [chemical binding]; other site 663951002832 HMMPfam hit to PF05175, MTS, score 2.3e-85 663951002833 RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cl17585 663951002834 RNA polymerase Rpb2, domain 2; Region: RNA_pol_Rpb2_2; pfam04561 663951002835 DNA-directed RNA polymerase subunit beta; Reviewed; Region: rpoB; PRK00405 663951002836 RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cd00653 663951002837 RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cd00653 663951002838 RPB10 interaction site [polypeptide binding]; other site 663951002839 RPB1 interaction site [polypeptide binding]; other site 663951002840 RPB11 interaction site [polypeptide binding]; other site 663951002841 RPB3 interaction site [polypeptide binding]; other site 663951002842 RPB12 interaction site [polypeptide binding]; other site 663951002843 HMMPfam hit to PF04563, RNA_pol_Rpb2_1, score 3.5e-57 663951002844 HMMPfam hit to PF04561, RNA_pol_Rpb2_2, score 2.5e-24 663951002845 HMMPfam hit to PF04561, RNA_pol_Rpb2_2, score 2e-08 663951002846 HMMPfam hit to PF04565, RNA_pol_Rpb2_3, score 2.3e-42 663951002847 HMMPfam hit to PF00562, RNA_pol_Rpb2_6, score 8.8e-221 663951002848 PS01166 RNA polymerases beta chain signature. 663951002849 PS00017 ATP/GTP-binding site motif A (P-loop). 663951002850 HMMPfam hit to PF04560, RNA_pol_Rpb2_7, score 8.1e-50 663951002851 DNA-directed RNA polymerase subunit beta'; Provisional; Region: PRK00566 663951002852 RNA polymerase Rpb1, domain 1; Region: RNA_pol_Rpb1_1; pfam04997 663951002853 RNA polymerase I subunit A N-terminus; Region: RPOLA_N; smart00663 663951002854 RNA polymerase Rpb1, domain 3; Region: RNA_pol_Rpb1_3; pfam04983 663951002855 RNA polymerase Rpb1, domain 4; Region: RNA_pol_Rpb1_4; pfam05000 663951002856 Largest subunit (beta') of Bacterial DNA-dependent RNA polymerase (RNAP), C-terminal domain; Region: RNAP_beta'_C; cd02655 663951002857 Rpb1 (beta') - Rpb6 (omega) interaction site [polypeptide binding]; other site 663951002858 Rpb1 (beta') - Rpb2 (beta) interaction site [polypeptide binding]; other site 663951002859 G-loop; other site 663951002860 DNA binding site [nucleotide binding] 663951002861 HMMPfam hit to PF04997, RNA_pol_Rpb1_1, score 1.7e-162 663951002862 HMMPfam hit to PF00623, RNA_pol_Rpb1_2, score 2.8e-83 663951002863 HMMPfam hit to PF04983, RNA_pol_Rpb1_3, score 3e-71 663951002864 HMMPfam hit to PF05000, RNA_pol_Rpb1_4, score 2.8e-29 663951002865 HMMPfam hit to PF04998, RNA_pol_Rpb1_5, score 2.7e-85 663951002866 PS00290 Immunoglobulins and major histocompatibility complex proteins signature. 663951002867 putative ribosomal protein L7Ae-like; Provisional; Region: PRK13600 663951002868 S12-like family, 30S ribosomal protein S12 subfamily; S12 is located at the interface of the large and small ribosomal subunits of prokaryotes, chloroplasts and mitochondria, where it plays an important role in both tRNA and ribosomal subunit...; Region: Ribosomal_S12; cd03368 663951002869 S17 interaction site [polypeptide binding]; other site 663951002870 S8 interaction site; other site 663951002871 16S rRNA interaction site [nucleotide binding]; other site 663951002872 streptomycin interaction site [chemical binding]; other site 663951002873 23S rRNA interaction site [nucleotide binding]; other site 663951002874 aminoacyl-tRNA interaction site (A-site) [nucleotide binding]; other site 663951002875 HMMPfam hit to PF00164, Ribosomal_S12, score 1.6e-64 663951002876 PS00055 Ribosomal protein S12 signature. 663951002877 30S ribosomal protein S7; Validated; Region: PRK05302 663951002878 HMMPfam hit to PF00177, Ribosomal_S7, score 1.5e-86 663951002879 PS00052 Ribosomal protein S7 signature. 663951002880 elongation factor G; Reviewed; Region: PRK00007 663951002881 Elongation factor G (EF-G) family involved in both the elongation and ribosome recycling phases of protein synthesis; Region: EF-G; cd01886 663951002882 G1 box; other site 663951002883 putative GEF interaction site [polypeptide binding]; other site 663951002884 GTP/Mg2+ binding site [chemical binding]; other site 663951002885 Switch I region; other site 663951002886 G2 box; other site 663951002887 G3 box; other site 663951002888 Switch II region; other site 663951002889 G4 box; other site 663951002890 G5 box; other site 663951002891 EFG_mtEFG_II: this subfamily represents the domain II of elongation factor G (EF-G) in bacteria and, the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2)_like proteins found in eukaryotes. During the process of peptide synthesis...; Region: EFG_mtEFG_II; cd04088 663951002892 EFG_mtEFG1_IV: domains similar to domain IV of the bacterial translational elongation factor (EF) EF-G. Included in this group is a domain of mitochondrial Elongation factor G1 (mtEFG1) proteins homologous to domain IV of EF-G. Eukaryotic cells harbor 2...; Region: EFG_mtEFG1_IV; cd01434 663951002893 EFG_mtEFG_C: domains similar to the C-terminal domain of the bacterial translational elongation factor (EF) EF-G. Included in this group is the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2) proteins. Eukaryotic cells harbor 2...; Region: EFG_mtEFG_C; cd03713 663951002894 HMMPfam hit to PF00009, GTP_EFTU, score 3.4e-111 663951002895 PS00017 ATP/GTP-binding site motif A (P-loop). 663951002896 PS00301 GTP-binding elongation factors signature. 663951002897 HMMPfam hit to PF03144, GTP_EFTU_D2, score 3.8e-18 663951002898 HMMPfam hit to PF03764, EFG_IV, score 1.4e-64 663951002899 HMMPfam hit to PF00679, EFG_C, score 8.4e-51 663951002900 elongation factor Tu; Reviewed; Region: PRK00049 663951002901 Elongation Factor Tu (EF-Tu) GTP-binding proteins; Region: EF_Tu; cd01884 663951002902 G1 box; other site 663951002903 GEF interaction site [polypeptide binding]; other site 663951002904 GTP/Mg2+ binding site [chemical binding]; other site 663951002905 Switch I region; other site 663951002906 G2 box; other site 663951002907 G3 box; other site 663951002908 Switch II region; other site 663951002909 G4 box; other site 663951002910 G5 box; other site 663951002911 EFTU_II: Elongation factor Tu domain II. Elongation factors Tu (EF-Tu) are three-domain GTPases with an essential function in the elongation phase of mRNA translation. The GTPase center of EF-Tu is in the N-terminal domain (domain I), also known as the...; Region: EFTU_II; cd03697 663951002912 Domain III of elongation factor (EF) Tu. Ef-Tu consists of three structural domains, designated I, II and III. Domain III adopts a beta barrel structure. Domain III is involved in binding to both charged tRNA and binding to elongation factor Ts (EF-Ts); Region: EFTU_III; cd03707 663951002913 Antibiotic Binding Site [chemical binding]; other site 663951002914 HMMPfam hit to PF00009, GTP_EFTU, score 1.5e-97 663951002915 PS00017 ATP/GTP-binding site motif A (P-loop). 663951002916 PS00301 GTP-binding elongation factors signature. 663951002917 HMMPfam hit to PF03144, GTP_EFTU_D2, score 6.9e-27 663951002918 HMMPfam hit to PF03143, GTP_EFTU_D3, score 6.7e-62 663951002919 Metal-dependent amidase/aminoacylase/carboxypeptidase [General function prediction only]; Region: AbgB; COG1473 663951002920 M20 Peptidase Aminoacylase 1 family; Region: M20_Acy1; cd03886 663951002921 metal binding site [ion binding]; metal-binding site 663951002922 dimer interface [polypeptide binding]; other site 663951002923 HMMPfam hit to PF01546, Peptidase_M20, score 6.6e-61 663951002924 HMMPfam hit to PF07687, M20_dimer, score 3.3e-06 663951002925 pyridoxal phosphate-dependent acyltransferase, putative; Region: gly_Cac_T_rel; TIGR01825 663951002926 KBL_like; this family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to serine palmitoyltransferase (SPT), 5-aminolevulinate synthase (ALAS); Region: KBL_like; cd06454 663951002927 substrate-cofactor binding pocket; other site 663951002928 pyridoxal 5'-phosphate binding site [chemical binding]; other site 663951002929 catalytic residue [active] 663951002930 HMMPfam hit to PF00155, Aminotran_1_2, score 4.8e-76 663951002931 PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 663951002932 chaperone protein HchA; Provisional; Region: PRK04155 663951002933 Type 1 glutamine amidotransferase (GATase1)-like domain found in Escherichia coli Hsp31 protein (EcHsp31); Region: GATase1_EcHsp31_like; cd03148 663951002934 dimer interface [polypeptide binding]; other site 663951002935 metal binding site [ion binding]; metal-binding site 663951002936 potential oxyanion hole; other site 663951002937 potential catalytic triad [active] 663951002938 conserved cys residue [active] 663951002939 HMMPfam hit to PF01965, DJ-1_PfpI, score 0.00037 663951002940 ribulokinase; Provisional; Region: PRK04123 663951002941 Ribulokinases; belongs to the FGGY family of carbohydrate kinases; Region: FGGY_RBK; cd07781 663951002942 N- and C-terminal domain interface [polypeptide binding]; other site 663951002943 active site 663951002944 MgATP binding site [chemical binding]; other site 663951002945 catalytic site [active] 663951002946 metal binding site [ion binding]; metal-binding site 663951002947 carbohydrate binding site [chemical binding]; other site 663951002948 homodimer interface [polypeptide binding]; other site 663951002949 HMMPfam hit to PF00370, FGGY_N, score 1.7e-07 663951002950 HMMPfam hit to PF02782, FGGY_C, score 5.6e-12 663951002951 Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451 663951002952 Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931 663951002953 NAD(P) binding site [chemical binding]; other site 663951002954 active site 663951002955 HMMPfam hit to PF01370, Epimerase, score 5.2e-18 663951002956 branched-chain amino acid aminotransferase; Provisional; Region: PRK13357 663951002957 BCAT_beta_family: Branched-chain aminotransferase catalyses the transamination of the branched-chain amino acids leusine, isoleucine and valine to their respective alpha-keto acids, alpha-ketoisocaproate, alpha-keto-beta-methylvalerate and...; Region: BCAT_beta_family; cd01557 663951002958 homodimer interface [polypeptide binding]; other site 663951002959 substrate-cofactor binding pocket; other site 663951002960 catalytic residue [active] 663951002961 HMMPfam hit to PF01063, Aminotran_4, score 2.9e-137 663951002962 PS00770 Aminotransferases class-IV signature. 663951002963 Predicted phosphatases [General function prediction only]; Region: Gph; COG0546 663951002964 Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427 663951002965 motif II; other site 663951002966 HMMPfam hit to PF00702, Hydrolase, score 1.3e-27 663951002967 Deoxynucleoside kinases [Nucleotide transport and metabolism]; Region: COG1428 663951002968 Deoxyribonucleoside kinase (dNK) catalyzes the phosphorylation of deoxyribonucleosides to yield corresponding monophosphates (dNMPs). This family consists of various deoxynucleoside kinases including deoxyribo- cytidine (EC 2.7.1.74), guanosine (EC 2.7.1; Region: dNK; cd01673 663951002969 Substrate-binding site [chemical binding]; other site 663951002970 Substrate specificity [chemical binding]; other site 663951002971 HMMPfam hit to PF01712, dNK, score 8.7e-47 663951002972 PS00017 ATP/GTP-binding site motif A (P-loop). 663951002973 Deoxynucleoside kinases [Nucleotide transport and metabolism]; Region: COG1428 663951002974 Deoxyribonucleoside kinase (dNK) catalyzes the phosphorylation of deoxyribonucleosides to yield corresponding monophosphates (dNMPs). This family consists of various deoxynucleoside kinases including deoxyribo- cytidine (EC 2.7.1.74), guanosine (EC 2.7.1; Region: dNK; cd01673 663951002975 Substrate-binding site [chemical binding]; other site 663951002976 Substrate specificity [chemical binding]; other site 663951002977 HMMPfam hit to PF01712, dNK, score 2.3e-21 663951002978 PS00017 ATP/GTP-binding site motif A (P-loop). 663951002979 Nucleoside deaminases include adenosine, guanine and cytosine deaminases. These enzymes are Zn dependent and catalyze the deamination of nucleosides. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a...; Region: nucleoside_deaminase; cd01285 663951002980 nucleoside/Zn binding site; other site 663951002981 dimer interface [polypeptide binding]; other site 663951002982 catalytic motif [active] 663951002983 HMMPfam hit to PF00383, dCMP_cyt_deam_1, score 1.4e-43 663951002984 PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 663951002985 Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427 663951002986 haloacid dehalogenase-like hydrolase; Region: Hydrolase_3; pfam08282 663951002987 active site 663951002988 motif I; other site 663951002989 motif II; other site 663951002990 Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427 663951002991 PS01228 Hypothetical cof family signature 1. 663951002992 HMMPfam hit to PF08282, Hydrolase_3, score 2.9e-96 663951002993 PS01229 Hypothetical cof family signature 2. 663951002994 Predicted flavoprotein [General function prediction only]; Region: COG0431 663951002995 NADPH-dependent FMN reductase; Region: FMN_red; pfam03358 663951002996 HMMPfam hit to PF03358, FMN_red, score 6.3e-19 663951002997 YSIRK type signal peptide; Region: YSIRK_signal; pfam04650 663951002998 C-terminus of bacterial fibrinogen-binding adhesin; Region: SdrG_C_C; pfam10425 663951002999 Cna protein B-type domain; Region: Cna_B; pfam05738 663951003000 Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620 663951003001 HMMPfam hit to PF04650, YSIRK_signal, score 7.2e-13 663951003002 2 probable transmembrane helices predicted for SATW20_06310 by TMHMM2.0 at aa 21-43 and 899-916 663951003003 HMMPfam hit to PF05738, Cna_B, score 7.6e-24 663951003004 HMMPfam hit to PF05738, Cna_B, score 1.1e-20 663951003005 HMMPfam hit to PF00746, Gram_pos_anchor, score 1.9e-12 663951003006 PS00343 Gram-positive cocci surface proteins 'anchoring' hexapeptide. 663951003007 YSIRK type signal peptide; Region: YSIRK_signal; pfam04650 663951003008 C-terminus of bacterial fibrinogen-binding adhesin; Region: SdrG_C_C; pfam10425 663951003009 Cna protein B-type domain; Region: Cna_B; pfam05738 663951003010 Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620 663951003011 Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620 663951003012 Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620 663951003013 Cna protein B-type domain; Region: Cna_B; pfam05738 663951003014 HMMPfam hit to PF04650, YSIRK_signal, score 2.9e-12 663951003015 HMMPfam hit to PF05738, Cna_B, score 3.6e-20 663951003016 HMMPfam hit to PF05738, Cna_B, score 3e-25 663951003017 HMMPfam hit to PF02412, TSP_3, score 0.71 663951003018 HMMPfam hit to PF05738, Cna_B, score 3.5e-21 663951003019 HMMPfam hit to PF02412, TSP_3, score 4.6 663951003020 HMMPfam hit to PF05738, Cna_B, score 2.3e-22 663951003021 HMMPfam hit to PF02412, TSP_3, score 1.9 663951003022 HMMPfam hit to PF05738, Cna_B, score 2.3e-20 663951003023 HMMPfam hit to PF00746, Gram_pos_anchor, score 2.2e-12 663951003024 1 probable transmembrane helix predicted for SATW20_06320 by TMHMM2.0 at aa 1357-1374 663951003025 YSIRK type signal peptide; Region: YSIRK_signal; pfam04650 663951003026 C-terminus of bacterial fibrinogen-binding adhesin; Region: SdrG_C_C; pfam10425 663951003027 Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620 663951003028 Cna protein B-type domain; Region: Cna_B; pfam05738 663951003029 Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620 663951003030 HMMPfam hit to PF04650, YSIRK_signal, score 2.9e-12 663951003031 2 probable transmembrane helices predicted for SATW20_06330 by TMHMM2.0 at aa 23-45 and 1113-1130 663951003032 HMMPfam hit to PF02412, TSP_3, score 0.91 663951003033 HMMPfam hit to PF05738, Cna_B, score 1.1e-19 663951003034 HMMPfam hit to PF02412, TSP_3, score 3.3 663951003035 HMMPfam hit to PF05738, Cna_B, score 4.3e-20 663951003036 HMMPfam hit to PF02412, TSP_3, score 1.9 663951003037 HMMPfam hit to PF05738, Cna_B, score 3.2e-20 663951003038 HMMPfam hit to PF00746, Gram_pos_anchor, score 1.9e-12 663951003039 PS00343 Gram-positive cocci surface proteins 'anchoring' hexapeptide. 663951003040 Domain of unknown function (DUF1975); Region: DUF1975; pfam09318 663951003041 This family is most closely related to the GT1 family of glycosyltransferases and is named after gtfA in Streptococcus gordonii, where it plays a role in the O-linked glycosylation of GspB, a cell surface glycoprotein involved in platelet binding. In...; Region: GT1_gtfA_like; cd04949 663951003042 Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438 663951003043 HMMPfam hit to PF09318, DUF1975, score 2.3e-132 663951003044 HMMPfam hit to PF00534, Glycos_transf_1, score 1.7e-44 663951003045 Domain of unknown function (DUF1975); Region: DUF1975; pfam09318 663951003046 This family is most closely related to the GT1 family of glycosyltransferases and is named after gtfA in Streptococcus gordonii, where it plays a role in the O-linked glycosylation of GspB, a cell surface glycoprotein involved in platelet binding. In...; Region: GT1_gtfA_like; cd04949 663951003047 Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438 663951003048 HMMPfam hit to PF00534, Glycos_transf_1, score 1.2e-32 663951003049 HMMPfam hit to PF09318, DUF1975, score 9.5e-143 663951003050 putative GTP cyclohydrolase; Provisional; Region: PRK13674 663951003051 HMMPfam hit to PF02649, DUF198, score 3.6e-59 663951003052 bacillithiol biosynthesis deacetylase BshB2; Region: thiol_BshB2; TIGR04000 663951003053 HMMPfam hit to PF02585, PIG-L, score 1.7e-46 663951003054 Protein of unknown function (DUF1806); Region: DUF1806; pfam08830 663951003055 HMMPfam hit to PF08830, DUF1806, score 1.2e-86 663951003056 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase [Carbohydrate transport and metabolism]; Region: NagB; COG0363 663951003057 GlcN6P_deaminase: Glucosamine-6-phosphate (GlcN6P) deaminase subfamily; GlcN6P deaminase catalyzes the reversible conversion of GlcN6P to D-fructose-6-phosphate (Fru6P) and ammonium. The reaction is an aldo-keto isomerization coupled with an amination or...; Region: GlcN6P_deaminase; cd01399 663951003058 active site 663951003059 trimer interface [polypeptide binding]; other site 663951003060 allosteric site; other site 663951003061 active site lid [active] 663951003062 hexamer (dimer of trimers) interface [polypeptide binding]; other site 663951003063 HMMPfam hit to PF01182, Glucosamine_iso, score 1.5e-46 663951003064 3-Keto-L-gulonate 6-phosphate decarboxylase (KGPDC) and D-arabino-3-hexulose-6-phosphate synthase (HPS). KGPDC catalyzes the formation of L-xylulose 5-phosphate and carbon dioxide from 3-keto-L-gulonate 6-phosphate as part of the anaerobic pathway for...; Region: KGPDC_HPS; cd04726 663951003065 active site 663951003066 dimer interface [polypeptide binding]; other site 663951003067 magnesium binding site [ion binding]; other site 663951003068 HMMPfam hit to PF00215, OMPdecase, score 6.6e-54 663951003069 Hexulose-6-phosphate isomerase (PHI). PHI is a member of the SIS (Sugar ISomerase domain) superfamily. In the ribulose monophosphate pathway of formaldehyde fixation, hexulose-6-phosphate synthase catalyzes the condensation of ribulose-5-phosphate with...; Region: SIS_PHI; cd05005 663951003070 tetramer interface [polypeptide binding]; other site 663951003071 Transcriptional regulators [Transcription]; Region: RpiR; COG1737 663951003072 active site 663951003073 HMMPfam hit to PF01380, SIS, score 4.3e-18 663951003074 Predicted phosphatases [General function prediction only]; Region: Gph; COG0546 663951003075 Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427 663951003076 motif II; other site 663951003077 HMMPfam hit to PF00702, Hydrolase, score 2.1e-29 663951003078 proline/glycine betaine transporter; Provisional; Region: PRK10642 663951003079 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 663951003080 putative substrate translocation pore; other site 663951003081 12 probable transmembrane helices predicted for SATW20_06430 by TMHMM2.0 at aa 20-42, 62-84, 91-113,118-140, 160-182, 192-211, 247-269, 279-301, 313-332,337-354, 375-397 and 407-429 663951003082 HMMPfam hit to PF07690, MFS_1, score 2e-25 663951003083 PS00217 Sugar transport proteins signature 2. 663951003084 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II [Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism]; Region: CaiC; COG0318 663951003085 Adenylate forming domain, Class I; Region: AFD_class_I; cd04433 663951003086 acyl-activating enzyme (AAE) consensus motif; other site 663951003087 AMP binding site [chemical binding]; other site 663951003088 active site 663951003089 CoA binding site [chemical binding]; other site 663951003090 HMMPfam hit to PF00501, AMP-binding, score 2.3e-23 663951003091 PS00455 Putative AMP-binding domain signature. 663951003092 Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751 663951003093 acetyl-CoA acetyltransferases; Region: AcCoA-C-Actrans; TIGR01930 663951003094 dimer interface [polypeptide binding]; other site 663951003095 active site 663951003096 HMMPfam hit to PF00108, Thiolase_N, score 2.3e-54 663951003097 HMMPfam hit to PF02803, Thiolase_C, score 9.6e-34 663951003098 PS00737 Thiolases signature 2. 663951003099 4-amino-5-hydroxymethyl-2-methyl-pyrimidine phosphate kinase (HMPP-kinase) catalyzes two consecutive phosphorylation steps in the thiamine phosphate biosynthesis pathway, leading to the synthesis of vitamin B1. The first step is the phosphorylation of...; Region: HMPP_kinase; cd01169 663951003100 dimer interface [polypeptide binding]; other site 663951003101 substrate binding site [chemical binding]; other site 663951003102 ATP binding site [chemical binding]; other site 663951003103 HMMPfam hit to PF08543, Phos_pyr_kin, score 2.2e-112 663951003104 PS00017 ATP/GTP-binding site motif A (P-loop). 663951003105 Family 1 of Uracil-DNA glycosylase (UDG) enzymes; Region: UDG_F1; cd10027 663951003106 ligand binding site [chemical binding]; other site 663951003107 active site 663951003108 UGI interface [polypeptide binding]; other site 663951003109 catalytic site [active] 663951003110 HMMPfam hit to PF03167, UDG, score 2e-69 663951003111 PS00130 Uracil-DNA glycosylase signature. 663951003112 Uncharacterized small membrane protein [Function unknown]; Region: COG2363 663951003113 4 probable transmembrane helices predicted for SATW20_06520 by TMHMM2.0 at aa 4-26, 47-64, 68-87 and 94-116 663951003114 HMMPfam hit to PF04241, DUF423, score 6e-64 663951003115 Amino acid transporters [Amino acid transport and metabolism]; Region: PotE; COG0531 663951003116 12 probable transmembrane helices predicted for SATW20_06530 by TMHMM2.0 at aa 21-40, 50-72, 93-115,138-160, 173-195, 210-229, 249-271, 291-313, 346-365,375-397, 410-429 and 434-456 663951003117 HMMPfam hit to PF00324, AA_permease, score 7.3e-05 663951003118 Uncharacterized conserved protein [Function unknown]; Region: COG3610 663951003119 4 probable transmembrane helices predicted for SATW20_06540 by TMHMM2.0 at aa 2-24, 44-66, 78-100 and 110-132 663951003120 Uncharacterized conserved protein [Function unknown]; Region: COG2966 663951003121 Protein of unknown function (DUF1212); Region: DUF1212; pfam06738 663951003122 4 probable transmembrane helices predicted for SATW20_06550 by TMHMM2.0 at aa 138-160, 170-192, 197-219 and 234-253 663951003123 HMMPfam hit to PF06738, DUF1212, score 1e-48 663951003124 putative heme peroxidase; Provisional; Region: PRK12276 663951003125 HMMPfam hit to PF06778, Chlor_dismutase, score 2.5e-118 663951003126 phosphotransacetylase; Reviewed; Region: eutD; PRK09653 663951003127 HMMPfam hit to PF01515, PTA_PTB, score 8.5e-162 663951003128 Lipoate-protein ligase A [Coenzyme metabolism]; Region: LplA; COG0095 663951003129 mevalonate kinase; Region: mevalon_kin; TIGR00549 663951003130 GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288 663951003131 GHMP kinases C terminal; Region: GHMP_kinases_C; pfam08544 663951003132 HMMPfam hit to PF00288, GHMP_kinases_N, score 1e-19 663951003133 PS00627 GHMP kinases putative ATP-binding domain. 663951003134 HMMPfam hit to PF08544, GHMP_kinases_C, score 1.9e-11 663951003135 Mevalonate pyrophosphate decarboxylase [Lipid metabolism]; Region: MVD1; COG3407 663951003136 diphosphomevalonate decarboxylase; Region: PLN02407 663951003137 HMMPfam hit to PF00288, GHMP_kinases_N, score 1.9e-14 663951003138 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 663951003139 HMMPfam hit to PF08544, GHMP_kinases_C, score 2.5e-08 663951003140 phosphomevalonate kinase, ERG8-type, Gram-positive branch; Region: Pmev_kin_Gr_pos; TIGR01220 663951003141 GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288 663951003142 GHMP kinases C terminal; Region: GHMP_kinases_C; pfam08544 663951003143 HMMPfam hit to PF00288, GHMP_kinases_N, score 5.3e-13 663951003144 HMMPfam hit to PF08544, GHMP_kinases_C, score 5.8e-09 663951003145 Protein of unknown function (DUF1450); Region: DUF1450; cl11488 663951003146 pyridine nucleotide-disulfide oxidoreductase; Provisional; Region: PRK07251 663951003147 ubiquinone biosynthesis hydroxylase family protein; Provisional; Region: PRK07608; cl17314 663951003148 Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070 663951003149 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852 663951003150 HMMPfam hit to PF02852, Pyr_redox_dim, score 1.2e-25 663951003151 HMMPfam hit to PF07992, Pyr_redox_2, score 1.9e-45 663951003152 HMMPfam hit to PF00070, Pyr_redox, score 7.4e-31 663951003153 PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 663951003154 PS00017 ATP/GTP-binding site motif A (P-loop). 663951003155 Predicted transcriptional regulator [Transcription]; Region: COG1959 663951003156 Transcriptional regulator; Region: Rrf2; pfam02082 663951003157 HMMPfam hit to PF02082, Rrf2, score 2.2e-20 663951003158 Predicted helix-turn-helix motif with score 1199.000, SD 3.27 at aa 23-44, sequence FNSSSLAELTCLNPVQLRRVTT 663951003159 LXG domain of WXG superfamily; Region: LXG; pfam04740 663951003160 1 probable transmembrane helix predicted for SATW20_06650 by TMHMM2.0 at aa 389-411 663951003161 Protein of unknown function (DUF443); Region: DUF443; pfam04276 663951003162 HMMPfam hit to PF04276, DUF443, score 1.8e-70 663951003163 5 probable transmembrane helices predicted for SATW20_06660 by TMHMM2.0 at aa 23-45, 67-84, 99-118,148-170 and 175-197 663951003164 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 663951003165 Protein of unknown function (DUF443); Region: DUF443; pfam04276 663951003166 HMMPfam hit to PF04276, DUF443, score 2.6e-84 663951003167 5 probable transmembrane helices predicted for SATW20_06670 by TMHMM2.0 at aa 26-48, 68-87, 102-121,148-170 and 174-193 663951003168 Protein of unknown function (DUF443); Region: DUF443; pfam04276 663951003169 HMMPfam hit to PF04276, DUF443, score 7.3e-79 663951003170 3 probable transmembrane helices predicted for SATW20_06680 by TMHMM2.0 at aa 99-118, 147-169 and 174-196 663951003171 Protein of unknown function (DUF443); Region: DUF443; pfam04276 663951003172 HMMPfam hit to PF04276, DUF443, score 2.2e-79 663951003173 5 probable transmembrane helices predicted for SATW20_06690 by TMHMM2.0 at aa 23-45, 70-89, 99-118,138-160 and 175-197 663951003174 Protein of unknown function (DUF443); Region: DUF443; pfam04276 663951003175 HMMPfam hit to PF04276, DUF443, score 1.5e-119 663951003176 5 probable transmembrane helices predicted for SATW20_06700 by TMHMM2.0 at aa 23-45, 69-84, 99-116,137-159 and 174-196 663951003177 Protein of unknown function (DUF443); Region: DUF443; pfam04276 663951003178 HMMPfam hit to PF04276, DUF443, score 1.6e-125 663951003179 5 probable transmembrane helices predicted for SATW20_06710 by TMHMM2.0 at aa 23-45, 69-86, 99-118,147-169 and 176-198 663951003180 CDS contains a nonsense mutation (ochre) after codon 56 663951003181 HMMPfam hit to PF04276, DUF443, score 1.3e-72 663951003182 5 probable transmembrane helices predicted for SATW20_06720 by TMHMM2.0 at aa 23-45, 66-83, 98-117,146-168 and 173-195 663951003183 Protein of unknown function (DUF443); Region: DUF443; pfam04276 663951003184 HMMPfam hit to PF04276, DUF443, score 1.3e-80 663951003185 5 probable transmembrane helices predicted for SATW20_06730 by TMHMM2.0 at aa 24-46, 70-89, 99-118,138-160 and 175-197 663951003186 Protein of unknown function (DUF443); Region: DUF443; pfam04276 663951003187 HMMPfam hit to PF04276, DUF443, score 2.9e-78 663951003188 5 probable transmembrane helices predicted for SATW20_06740 by TMHMM2.0 at aa 23-45, 67-84, 99-118,148-170 and 175-197 663951003189 Protein of unknown function (DUF443); Region: DUF443; pfam04276 663951003190 HMMPfam hit to PF04276, DUF443, score 8.8e-67 663951003191 5 probable transmembrane helices predicted for SATW20_06750 by TMHMM2.0 at aa 4-21, 46-65, 75-94, 123-145 and 150-172 663951003192 Protein of unknown function (DUF443); Region: DUF443; pfam04276 663951003193 HMMPfam hit to PF04276, DUF443, score 1.5e-114 663951003194 4 probable transmembrane helices predicted for SATW20_06760 by TMHMM2.0 at aa 24-46, 100-117, 138-160 and 175-197 663951003195 Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660 663951003196 Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248 663951003197 active site 663951003198 catalytic tetrad [active] 663951003199 HMMPfam hit to PF00248, Aldo_ket_red, score 5.3e-74 663951003200 PS00062 Aldo/keto reductase family signature 2. 663951003201 Multimeric flavodoxin WrbA [General function prediction only]; Region: WrbA; COG0655 663951003202 NADPH-dependent FMN reductase; Region: FMN_red; pfam03358 663951003203 HMMPfam hit to PF03358, FMN_red, score 0.00038 663951003204 Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673 663951003205 N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301 663951003206 Coenzyme A binding pocket [chemical binding]; other site 663951003207 HMMPfam hit to PF00583, Acetyltransf_1, score 1.1e-14 663951003208 HD superfamily phosphohydrolases [General function prediction only]; Region: COG1078 663951003209 Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077 663951003210 Zn2+ binding site [ion binding]; other site 663951003211 Mg2+ binding site [ion binding]; other site 663951003212 HMMPfam hit to PF01966, HD, score 1.4e-11 663951003213 YwhD family; Region: YwhD; pfam08741 663951003214 HMMPfam hit to PF08741, YwhD, score 2.3e-132 663951003215 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 663951003216 Cinnamyl alcohol dehydrogenases (CAD); Region: CAD3; cd08297 663951003217 ethanol-active dehydrogenase/acetaldehyde-active reductase; Provisional; Region: PRK09422 663951003218 NAD binding site [chemical binding]; other site 663951003219 substrate binding site [chemical binding]; other site 663951003220 catalytic Zn binding site [ion binding]; other site 663951003221 tetramer interface [polypeptide binding]; other site 663951003222 structural Zn binding site [ion binding]; other site 663951003223 HMMPfam hit to PF08240, ADH_N, score 7.7e-48 663951003224 PS00190 Cytochrome c family heme-binding site signature. 663951003225 PS00059 Zinc-containing alcohol dehydrogenases signature. 663951003226 HMMPfam hit to PF00107, ADH_zinc_N, score 3.1e-42 663951003227 PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 663951003228 Domain of unknown function (DUF1934); Region: DUF1934; cl01870 663951003229 HMMPfam hit to PF09148, DUF1934, score 8e-59 663951003230 arginyl-tRNA synthetase; Reviewed; Region: argS; PRK01611 663951003231 Arginyl tRNA synthetase N terminal domain; Region: Arg_tRNA_synt_N; pfam03485 663951003232 catalytic core domain of arginyl-tRNA synthetases; Region: ArgRS_core; cd00671 663951003233 active site 663951003234 HIGH motif; other site 663951003235 nucleotidyl transferase superfamily; Region: nt_trans; cl00015 663951003236 KMSK motif region; other site 663951003237 tRNA binding surface [nucleotide binding]; other site 663951003238 DALR anticodon binding domain; Region: DALR_1; smart00836 663951003239 anticodon binding site; other site 663951003240 HMMPfam hit to PF03485, Arg_tRNA_synt_N, score 3.9e-34 663951003241 HMMPfam hit to PF00750, tRNA-synt_1d, score 2.8e-91 663951003242 PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 663951003243 HMMPfam hit to PF05746, DALR_1, score 1.5e-50 663951003244 Uncharacterized protein related to Endonuclease III [DNA replication, recombination, and repair]; Region: COG2231 663951003245 endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056 663951003246 minor groove reading motif; other site 663951003247 helix-hairpin-helix signature motif; other site 663951003248 substrate binding pocket [chemical binding]; other site 663951003249 active site 663951003250 HMMPfam hit to PF00730, HhH-GPD, score 0.02 663951003251 ABC-type Fe3+-hydroxamate transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: FepB; COG0614 663951003252 Periplasmic binding protein YvrC. These proteins are predicted to function as initial receptors in ABC transport of metal ions in eubacteria and archaea. They belong to the TroA superfamily of periplasmic metal binding proteins that share a distinct...; Region: YvrC; cd01143 663951003253 putative binding site residues; other site 663951003254 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 663951003255 HMMPfam hit to PF01497, Peripla_BP_2, score 1.7e-28 663951003256 ABC-type enterobactin transport system, permease component [Inorganic ion transport and metabolism]; Region: FepG; COG4779 663951003257 Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550 663951003258 ABC-ATPase subunit interface; other site 663951003259 dimer interface [polypeptide binding]; other site 663951003260 putative PBP binding regions; other site 663951003261 10 probable transmembrane helices predicted for SATW20_06870 by TMHMM2.0 at aa 19-38, 58-80, 87-109,113-135, 142-164, 187-209, 222-241, 245-262, 275-297 and 302-321 663951003262 HMMPfam hit to PF01032, FecCD, score 8e-46 663951003263 Predicted hydrolase (HAD superfamily) [General function prediction only]; Region: COG1011 663951003264 Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427 663951003265 motif II; other site 663951003266 HMMPfam hit to PF00702, Hydrolase, score 7.2e-23 663951003267 PS00017 ATP/GTP-binding site motif A (P-loop). 663951003268 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596 663951003269 Putative lysophospholipase; Region: Hydrolase_4; pfam12146 663951003270 HMMPfam hit to PF00561, Abhydrolase_1, score 6.8e-08 663951003271 PS00017 ATP/GTP-binding site motif A (P-loop). 663951003272 5 probable transmembrane helices predicted for SATW20_06910 by TMHMM2.0 at aa 66-88, 98-120, 132-154,164-183 and 212-234 663951003273 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596 663951003274 Putative lysophospholipase; Region: Hydrolase_4; pfam12146 663951003275 HMMPfam hit to PF00561, Abhydrolase_1, score 2e-28 663951003276 staphylococcal accessory regulator family; Region: Staph_reg_Sar; TIGR01889 663951003277 Transcriptional regulators [Transcription]; Region: MarR; COG1846 663951003278 Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3238 663951003279 Protein of unknown function, DUF606; Region: DUF606; pfam04657 663951003280 9 probable transmembrane helices predicted for SATW20_06940 by TMHMM2.0 at aa 20-42, 57-79, 86-108,118-136, 148-170, 180-202, 221-243, 247-269 and 282-296 663951003281 HMMPfam hit to PF04657, DUF606, score 9.2e-33 663951003282 HMMPfam hit to PF04657, DUF606, score 2.2e-59 663951003283 Protein of unknown function (DUF2922); Region: DUF2922; pfam11148 663951003284 DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213 663951003285 active site 663951003286 DNA binding site [nucleotide binding] 663951003287 Int/Topo IB signature motif; other site 663951003288 HMMPfam hit to PF00589, Phage_integrase, score 3e-11 663951003289 Predicted helix-turn-helix motif with score 1046.000, SD 2.75 at aa 36-57, sequence HSGLKVSELLTITVSQVKRLIE 663951003290 putative monovalent cation/H+ antiporter subunit A; Reviewed; Region: PRK12646 663951003291 NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361 663951003292 Multisubunit Na+/H+ antiporter, MnhB subunit [Inorganic ion transport and metabolism]; Region: MnhB; COG2111 663951003293 21 probable transmembrane helices predicted for SATW20_06980 by TMHMM2.0 at aa 4-21, 30-52, 76-98, 111-128,132-154, 167-189, 209-231, 244-266, 271-293, 300-320,330-352, 385-407, 427-449, 473-495, 525-547, 591-613,628-647, 654-671, 676-698, 711-733 and 770-789 663951003294 HMMPfam hit to PF00662, Oxidored_q1_N, score 2.9e-06 663951003295 HMMPfam hit to PF00361, Oxidored_q1, score 1.8e-71 663951003296 putative monovalent cation/H+ antiporter subunit B; Reviewed; Region: PRK12574 663951003297 HMMPfam hit to PF04039, MnhB, score 5.8e-46 663951003298 4 probable transmembrane helices predicted for SATW20_06990 by TMHMM2.0 at aa 7-29, 34-56, 68-90 and 114-136 663951003299 putative monovalent cation/H+ antiporter subunit C; Reviewed; Region: PRK12660 663951003300 HMMPfam hit to PF00420, Oxidored_q2, score 6.1e-18 663951003301 3 probable transmembrane helices predicted for SATW20_07000 by TMHMM2.0 at aa 4-26, 28-50 and 70-92 663951003302 putative monovalent cation/H+ antiporter subunit D; Reviewed; Region: PRK12663 663951003303 NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361 663951003304 14 probable transmembrane helices predicted for SATW20_07010 by TMHMM2.0 at aa 5-23, 30-52, 77-99, 108-127,131-153, 160-182, 206-228, 235-257, 270-292, 299-321,326-348, 368-390, 405-427 and 451-473 663951003305 HMMPfam hit to PF00361, Oxidored_q1, score 1.7e-46 663951003306 putative monovalent cation/H+ antiporter subunit E; Reviewed; Region: PRK08965 663951003307 3 probable transmembrane helices predicted for SATW20_07020 by TMHMM2.0 at aa 25-47, 60-82 and 102-120 663951003308 HMMPfam hit to PF01899, MNHE, score 5e-05 663951003309 putative monovalent cation/H+ antiporter subunit F; Reviewed; Region: PRK12657 663951003310 3 probable transmembrane helices predicted for SATW20_07030 by TMHMM2.0 at aa 4-26, 38-60 and 70-92 663951003311 HMMPfam hit to PF04066, MrpF_PhaF, score 1.4e-21 663951003312 putative monovalent cation/H+ antiporter subunit G; Reviewed; Region: PRK12586 663951003313 HMMPfam hit to PF03334, PhaG_MnhG_YufB, score 2.1e-23 663951003314 3 probable transmembrane helices predicted for SATW20_07040 by TMHMM2.0 at aa 7-29, 49-71 and 73-95 663951003315 NhaP-type Na+/H+ and K+/H+ antiporters [Inorganic ion transport and metabolism]; Region: NhaP; COG0025 663951003316 Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: KefB; cl10482 663951003317 13 probable transmembrane helices predicted for SATW20_07050 by TMHMM2.0 at aa 7-24, 29-51, 84-106,111-133, 153-175, 180-202, 215-234, 238-255, 276-298,308-325, 327-349, 369-391 and 404-426 663951003318 HMMPfam hit to PF00999, Na_H_Exchanger, score 6.7e-40 663951003319 ABC-type metal ion transport system, periplasmic component/surface adhesin [Inorganic ion transport and metabolism]; Region: LraI; COG0803 663951003320 Metal binding protein PsaA. These proteins have been shown to function as initial receptors in ABC transport of Mn2+ and as surface adhesins in some eubacterial species. They belong to the TroA superfamily of periplasmic metal binding proteins that...; Region: PsaA; cd01137 663951003321 metal binding site [ion binding]; metal-binding site 663951003322 HMMPfam hit to PF01297, SBP_bac_9, score 4.1e-143 663951003323 PS00017 ATP/GTP-binding site motif A (P-loop). 663951003324 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 663951003325 ABC-type Mn2+/Zn2+ transport systems, permease components [Inorganic ion transport and metabolism]; Region: ZnuB; COG1108 663951003326 Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550 663951003327 ABC-ATPase subunit interface; other site 663951003328 dimer interface [polypeptide binding]; other site 663951003329 putative PBP binding regions; other site 663951003330 HMMPfam hit to PF00950, ABC-3, score 8.1e-106 663951003331 8 probable transmembrane helices predicted for SATW20_07070 by TMHMM2.0 at aa 13-35, 50-81, 93-115,130-152, 165-187, 192-214, 221-243 and 248-265 663951003332 ABC-type Mn/Zn transport systems, ATPase component [Inorganic ion transport and metabolism]; Region: ZnuC; COG1121 663951003333 ATP-binding cassette domain of the metal-type transporters; Region: ABC_Metallic_Cations; cd03235 663951003334 HMMPfam hit to PF00005, ABC_tran, score 2.9e-46 663951003335 PS00211 ABC transporters family signature. 663951003336 PS00017 ATP/GTP-binding site motif A (P-loop). 663951003337 Mn-dependent transcriptional regulator [Transcription]; Region: TroR; COG1321 663951003338 Iron dependent repressor, N-terminal DNA binding domain; Region: Fe_dep_repress; pfam01325 663951003339 Iron dependent repressor, metal binding and dimerisation domain; Region: Fe_dep_repr_C; pfam02742 663951003340 FeoA domain; Region: FeoA; pfam04023 663951003341 HMMPfam hit to PF01325, Fe_dep_repress, score 3.2e-30 663951003342 HMMPfam hit to PF02742, Fe_dep_repr_C, score 1.2e-31 663951003343 HMMPfam hit to PF04023, FeoA, score 2.8e-14 663951003344 Peptidase M50B-like; Region: Peptidase_M50B; pfam13398 663951003345 6 probable transmembrane helices predicted for SATW20_07100 by TMHMM2.0 at aa 7-29, 96-118, 125-144,148-165, 170-192 and 221-243 663951003346 PS00142 Neutral zinc metallopeptidases, zinc-binding region signature. 663951003347 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 663951003348 Teichoic acid biosynthesis proteins [Cell envelope biogenesis, outer membrane]; Region: WecG; COG1922 663951003349 The glycosyltransferase WecG/TagA superfamily contains Escherichia coli WecG, Bacillus subtilis TagA and related proteins. E. coli WecG is believed to be a UDP-N-acetyl-D-mannosaminuronic acid transferase, and is involved in enterobacterial common...; Region: Glyco_transf_WecG_TagA; cd06533 663951003350 HMMPfam hit to PF03808, Glyco_tran_WecB, score 1.4e-91 663951003351 teichoic acids export protein ATP-binding subunit; Provisional; Region: PRK13546 663951003352 ATP-binding cassette component of polysaccharide transport system; Region: ABC_KpsT_Wzt; cd03220 663951003353 Walker A/P-loop; other site 663951003354 ATP binding site [chemical binding]; other site 663951003355 Q-loop/lid; other site 663951003356 ABC transporter signature motif; other site 663951003357 Walker B; other site 663951003358 D-loop; other site 663951003359 H-loop/switch region; other site 663951003360 HMMPfam hit to PF00005, ABC_tran, score 8.5e-31 663951003361 PS00211 ABC transporters family signature. 663951003362 PS00017 ATP/GTP-binding site motif A (P-loop). 663951003363 ABC-type polysaccharide/polyol phosphate export systems, permease component [Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: TagG; COG1682 663951003364 ABC-2 type transporter; Region: ABC2_membrane; cl17235 663951003365 HMMPfam hit to PF01061, ABC2_membrane, score 2.1e-06 663951003366 6 probable transmembrane helices predicted for SATW20_07130 by TMHMM2.0 at aa 33-55, 70-89, 125-147,151-173, 185-207 and 240-259 663951003367 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 663951003368 Putative glycosyl/glycerophosphate transferases involved in teichoic acid biosynthesis TagF/TagB/EpsJ/RodC [Cell envelope biogenesis, outer membrane]; Region: TagB; COG1887 663951003369 HMMPfam hit to PF04464, Glyphos_transf, score 1.1e-12 663951003370 Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761 663951003371 active site 663951003372 HMMPfam hit to PF00535, Glycos_transf_2, score 5.5e-10 663951003373 nucleotidyl transferase superfamily; Region: nt_trans; cl00015 663951003374 Cytidylyltransferase; Region: CTP_transf_2; pfam01467 663951003375 active site 663951003376 nucleotide binding site [chemical binding]; other site 663951003377 HIGH motif; other site 663951003378 KMSKS motif; other site 663951003379 HMMPfam hit to PF01467, CTP_transf_2, score 8.7e-37 663951003380 D-alanyl-D-alanine carboxypeptidase [Cell envelope biogenesis, outer membrane]; Region: DacC; COG1686 663951003381 Beta-lactamase enzyme family; Region: Beta-lactamase2; cl17872 663951003382 Domain of unknown function (DUF1958); Region: DUF1958; pfam09211 663951003383 1 probable transmembrane helix predicted for SATW20_07170 by TMHMM2.0 at aa 401-423 663951003384 HMMPfam hit to PF09211, DUF1958, score 7.2e-46 663951003385 HMMPfam hit to PF00768, Peptidase_S11, score 9.5e-44 663951003386 ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132 663951003387 ABC transporter transmembrane region; Region: ABC_membrane; pfam00664 663951003388 ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201 663951003389 Walker A/P-loop; other site 663951003390 ATP binding site [chemical binding]; other site 663951003391 Q-loop/lid; other site 663951003392 ABC transporter signature motif; other site 663951003393 Walker B; other site 663951003394 D-loop; other site 663951003395 H-loop/switch region; other site 663951003396 6 probable transmembrane helices predicted for SATW20_07180 by TMHMM2.0 at aa 21-43, 58-80, 134-153,158-180, 238-260 and 270-292 663951003397 HMMPfam hit to PF00664, ABC_membrane, score 4.7e-42 663951003398 HMMPfam hit to PF00005, ABC_tran, score 1.1e-61 663951003399 PS00017 ATP/GTP-binding site motif A (P-loop). 663951003400 PS00211 ABC transporters family signature. 663951003401 Nucleoside permease [Nucleotide transport and metabolism]; Region: NupC; COG1972 663951003402 Na+ dependent nucleoside transporter N-terminus; Region: Nucleos_tra2_N; pfam01773 663951003403 Na+ dependent nucleoside transporter C-terminus; Region: Nucleos_tra2_C; pfam07662 663951003404 HMMPfam hit to PF01773, Nucleos_tra2_N, score 2.1e-30 663951003405 10 probable transmembrane helices predicted for SATW20_07200 by TMHMM2.0 at aa 2-21, 27-49, 62-81, 91-113,165-187, 192-214, 243-265, 294-316, 348-370 and 385-407 663951003406 HMMPfam hit to PF07662, Nucleos_tra2_C, score 7.4e-107 663951003407 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 663951003408 Uncharacterized conserved protein [Function unknown]; Region: COG1284 663951003409 Uncharacterized BCR, YitT family COG1284; Region: DUF161; pfam02588 663951003410 Uncharacterized protein conserved in bacteria (DUF2179); Region: DUF2179; pfam10035 663951003411 HMMPfam hit to PF02588, DUF161, score 8.3e-24 663951003412 5 probable transmembrane helices predicted for SATW20_07210 by TMHMM2.0 at aa 9-31, 41-63, 75-97, 112-134 and 147-166 663951003413 HMMPfam hit to PF02588, DUF161, score 2.8e-16 663951003414 ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components [Inorganic ion transport and metabolism / Coenzyme metabolism]; Region: FepC; COG1120 663951003415 ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214 663951003416 Walker A/P-loop; other site 663951003417 ATP binding site [chemical binding]; other site 663951003418 Q-loop/lid; other site 663951003419 ABC transporter signature motif; other site 663951003420 Walker B; other site 663951003421 D-loop; other site 663951003422 H-loop/switch region; other site 663951003423 HMMPfam hit to PF00005, ABC_tran, score 6e-61 663951003424 PS00017 ATP/GTP-binding site motif A (P-loop). 663951003425 PS00211 ABC transporters family signature. 663951003426 iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577 663951003427 Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550 663951003428 ABC-ATPase subunit interface; other site 663951003429 dimer interface [polypeptide binding]; other site 663951003430 putative PBP binding regions; other site 663951003431 9 probable transmembrane helices predicted for SATW20_07230 by TMHMM2.0 at aa 12-34, 63-85, 98-117,121-143, 155-177, 201-223, 244-266, 276-298 and 305-327 663951003432 HMMPfam hit to PF01032, FecCD, score 9.3e-118 663951003433 ABC-type enterobactin transport system, permease component [Inorganic ion transport and metabolism]; Region: FepG; COG4779 663951003434 Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550 663951003435 ABC-ATPase subunit interface; other site 663951003436 dimer interface [polypeptide binding]; other site 663951003437 putative PBP binding regions; other site 663951003438 9 probable transmembrane helices predicted for SATW20_07240 by TMHMM2.0 at aa 12-31, 65-82, 95-112,122-144, 151-173, 198-217, 247-269, 284-301 and 308-330 663951003439 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 663951003440 HMMPfam hit to PF01032, FecCD, score 2.4e-105 663951003441 PS00267 Tachykinin family signature. 663951003442 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 663951003443 dihydroxyacetone kinase subunit DhaK; Provisional; Region: PRK14481 663951003444 Dihydroxyacetone kinase [Carbohydrate transport and metabolism]; Region: DAK1; COG2376 663951003445 HMMPfam hit to PF02733, Dak1, score 3.7e-104 663951003446 Dihydroxyacetone kinase [Carbohydrate transport and metabolism]; Region: DAK1; COG2376 663951003447 dihydroxyacetone kinase, phosphoprotein-dependent, L subunit; Region: dha_L_ycgS; TIGR02365 663951003448 HMMPfam hit to PF02734, Dak2, score 1.7e-65 663951003449 phosphotransferase mannnose-specific family component IIA; Provisional; Region: PRK14484 663951003450 HMMPfam hit to PF03610, EIIA-man, score 7.9e-41 663951003451 Uncharacterized membrane protein [Function unknown]; Region: COG3949 663951003452 Solute carrier families 5 and 6-like; solute binding domain; Region: SLC5-6-like_sbd; cl00456 663951003453 Na binding site [ion binding]; other site 663951003454 HMMPfam hit to PF05525, Branch_AA_trans, score 0.0026 663951003455 10 probable transmembrane helices predicted for SATW20_07290 by TMHMM2.0 at aa 7-26, 36-55, 85-107,117-134, 141-163, 186-208, 215-237, 264-286, 299-321 and 325-344 663951003456 PS00251 TNF family signature. 663951003457 Esterase/lipase [Lipid metabolism]; Region: Aes; COG0657 663951003458 Esterases and lipases (includes fungal lipases, cholinesterases, etc.) These enzymes act on carboxylic esters (EC: 3.1.1.-). The catalytic apparatus involves three residues (catalytic triad): a serine, a glutamate or aspartate and a histidine.These...; Region: Esterase_lipase; cd00312 663951003459 substrate binding pocket [chemical binding]; other site 663951003460 Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326 663951003461 1 probable transmembrane helix predicted for SATW20_07300 by TMHMM2.0 at aa 7-26 663951003462 HMMPfam hit to PF07859, Abhydrolase_3, score 1.3e-18 663951003463 Acetyltransferases [General function prediction only]; Region: RimI; COG0456 663951003464 N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301 663951003465 Coenzyme A binding pocket [chemical binding]; other site 663951003466 N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182 663951003467 HMMPfam hit to PF00583, Acetyltransf_1, score 3.3e-16 663951003468 Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451 663951003469 Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931 663951003470 NAD(P) binding site [chemical binding]; other site 663951003471 active site 663951003472 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745 663951003473 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 663951003474 active site 663951003475 phosphorylation site [posttranslational modification] 663951003476 intermolecular recognition site; other site 663951003477 dimerization interface [polypeptide binding]; other site 663951003478 Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383 663951003479 DNA binding site [nucleotide binding] 663951003480 HMMPfam hit to PF00072, Response_reg, score 6.6e-26 663951003481 HMMPfam hit to PF00486, Trans_reg_C, score 7.6e-19 663951003482 Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642 663951003483 Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cl00080 663951003484 Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075 663951003485 ATP binding site [chemical binding]; other site 663951003486 Mg2+ binding site [ion binding]; other site 663951003487 G-X-G motif; other site 663951003488 2 probable transmembrane helices predicted for SATW20_07350 by TMHMM2.0 at aa 17-34 and 44-63 663951003489 HMMPfam hit to PF00512, HisKA, score 0.00047 663951003490 HMMPfam hit to PF02518, HATPase_c, score 7.7e-29 663951003491 ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136 663951003492 ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255 663951003493 Walker A/P-loop; other site 663951003494 ATP binding site [chemical binding]; other site 663951003495 Q-loop/lid; other site 663951003496 ABC transporter signature motif; other site 663951003497 Walker B; other site 663951003498 D-loop; other site 663951003499 H-loop/switch region; other site 663951003500 HMMPfam hit to PF00005, ABC_tran, score 8.1e-62 663951003501 PS00017 ATP/GTP-binding site motif A (P-loop). 663951003502 9 probable transmembrane helices predicted for SATW20_07370 by TMHMM2.0 at aa 28-50, 70-92, 124-146,167-189, 199-221, 256-278, 479-501, 535-557 and 567-589 663951003503 Phosphate transport regulator (distant homolog of PhoU) [Inorganic ion transport and metabolism]; Region: COG1392 663951003504 HMMPfam hit to PF01865, PhoU_div, score 1.2e-06 663951003505 Phosphate/sulphate permeases [Inorganic ion transport and metabolism]; Region: PitA; COG0306 663951003506 7 probable transmembrane helices predicted for SATW20_07390 by TMHMM2.0 at aa 2-24, 46-68, 81-103,108-130, 137-159, 221-243 and 309-331 663951003507 HMMPfam hit to PF01384, PHO4, score 4.1e-100 663951003508 Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118 663951003509 FOG: LysM repeat [Cell envelope biogenesis, outer membrane]; Region: LytE; COG1388 663951003510 Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118 663951003511 Surface antigen [General function prediction only]; Region: COG3942 663951003512 CHAP domain; Region: CHAP; pfam05257 663951003513 HMMPfam hit to PF05257, CHAP, score 6.2e-53 663951003514 HMMPfam hit to PF01476, LysM, score 2.1e-16 663951003515 HMMPfam hit to PF01476, LysM, score 1e-16 663951003516 Predicted helix-turn-helix motif with score 1169.000, SD 3.17 at aa 35-56, sequence ESLWSIAQKYNTSVESIKQNNQ 663951003517 Integral membrane protein, interacts with FtsH [General function prediction only]; Region: COG0670 663951003518 Inhibitor of apoptosis-promoting Bax1; Region: Bax1-I; pfam01027 663951003519 6 probable transmembrane helices predicted for SATW20_07410 by TMHMM2.0 at aa 21-43, 47-64, 71-93,103-125, 130-152 and 156-175 663951003520 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 663951003521 helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342 663951003522 HMMPfam hit to PF00165, HTH_AraC, score 0.0014 663951003523 Predicted helix-turn-helix motif with score 1764.000, SD 5.19 at aa 168-189, sequence LTLKSVADKLFVSKSNLSSQFH 663951003524 PS00041 Bacterial regulatory proteins, araC family signature. 663951003525 HMMPfam hit to PF00165, HTH_AraC, score 1.8e-11 663951003526 staphylococcal accessory regulator family; Region: Staph_reg_Sar; TIGR01889 663951003527 hypothetical protein; Provisional; Region: PRK12378 663951003528 HMMPfam hit to PF01709, DUF28, score 2e-119 663951003529 Cupin superfamily (DUF985); Region: Cupin_5; pfam06172 663951003530 HMMPfam hit to PF06172, Cupin_5, score 1.3e-86 663951003531 Predicted RNA-binding protein, associated with RNAses E/G family [General function prediction only]; Region: COG2306 663951003532 HMMPfam hit to PF04167, DUF402, score 1.3e-35 663951003533 Transcriptional regulator [Transcription]; Region: LysR; COG0583 663951003534 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 663951003535 The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466 663951003536 dimerization interface [polypeptide binding]; other site 663951003537 HMMPfam hit to PF00126, HTH_1, score 1.6e-15 663951003538 Predicted helix-turn-helix motif with score 1745.000, SD 5.13 at aa 16-37, sequence KTLRKAAEILYISQPAVTQRLK 663951003539 PS00044 Bacterial regulatory proteins, lysR family signature. 663951003540 HMMPfam hit to PF03466, LysR_substrate, score 2.6e-19 663951003541 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 663951003542 sugar efflux transporter; Region: 2A0120; TIGR00899 663951003543 putative substrate translocation pore; other site 663951003544 12 probable transmembrane helices predicted for SATW20_07480 by TMHMM2.0 at aa 13-35, 45-67, 80-99,103-125, 145-167, 171-193, 220-242, 257-279, 286-305,311-333, 340-359 and 369-391 663951003545 HMMPfam hit to PF07690, MFS_1, score 4.1e-32 663951003546 Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2839 663951003547 5 probable transmembrane helices predicted for SATW20_07490 by TMHMM2.0 at aa 2-21, 25-42, 47-69, 89-111 and 132-154 663951003548 HMMPfam hit to PF04306, DUF456, score 6.1e-89 663951003549 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 663951003550 Serine incorporator (Serinc); Region: Serinc; pfam03348 663951003551 4 probable transmembrane helices predicted for SATW20_07500 by TMHMM2.0 at aa 95-117, 127-149, 162-184 and 194-216 663951003552 N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301 663951003553 Coenzyme A binding pocket [chemical binding]; other site 663951003554 HMMPfam hit to PF00583, Acetyltransf_1, score 1.1e-14 663951003555 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 663951003556 Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302 663951003557 Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583 663951003558 HMMPfam hit to PF00583, Acetyltransf_1, score 4.4e-12 663951003559 Possible lysine decarboxylase; Region: Lysine_decarbox; pfam03641 663951003560 HMMPfam hit to PF03641, Lysine_decarbox, score 3.7e-68 663951003561 hypothetical protein; Validated; Region: PRK00124 663951003562 HMMPfam hit to PF02639, DUF188, score 3.8e-21 663951003563 recombination and DNA strand exchange inhibitor protein; Reviewed; Region: PRK00409 663951003564 undecaprenyl pyrophosphate phosphatase; Reviewed; Region: PRK00281 663951003565 6 probable transmembrane helices predicted for SATW20_07580 by TMHMM2.0 at aa 99-118, 128-145, 162-181,201-223, 236-258 and 268-287 663951003566 HMMPfam hit to PF02673, BacA, score 6.6e-141 663951003567 ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components [Energy production and conversion / Posttranslational modification, protein turnover, chaperones]; Region: CydD; COG4988 663951003568 ABC transporter transmembrane region; Region: ABC_membrane; pfam00664 663951003569 ATP-binding cassette domain of multidrug resistance protein-like transporters; Region: ABCC_MRP_Like; cd03228 663951003570 Walker A/P-loop; other site 663951003571 ATP binding site [chemical binding]; other site 663951003572 Q-loop/lid; other site 663951003573 ABC transporter signature motif; other site 663951003574 Walker B; other site 663951003575 D-loop; other site 663951003576 H-loop/switch region; other site 663951003577 5 probable transmembrane helices predicted for SATW20_07590 by TMHMM2.0 at aa 13-35, 50-72, 125-142,147-166 and 227-249 663951003578 HMMPfam hit to PF00664, ABC_membrane, score 2.2e-09 663951003579 HMMPfam hit to PF00005, ABC_tran, score 3e-51 663951003580 PS00017 ATP/GTP-binding site motif A (P-loop). 663951003581 PS00211 ABC transporters family signature. 663951003582 ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease components [Energy production and conversion / Posttranslational modification, protein turnover, chaperones]; Region: CydC; COG4987 663951003583 ABC transporter transmembrane region; Region: ABC_membrane; pfam00664 663951003584 ATP-binding cassette domain of multidrug resistance protein-like transporters; Region: ABCC_MRP_Like; cd03228 663951003585 Walker A/P-loop; other site 663951003586 ATP binding site [chemical binding]; other site 663951003587 Q-loop/lid; other site 663951003588 ABC transporter signature motif; other site 663951003589 Walker B; other site 663951003590 D-loop; other site 663951003591 H-loop/switch region; other site 663951003592 5 probable transmembrane helices predicted for SATW20_07600 by TMHMM2.0 at aa 13-35, 45-67, 123-145,149-171 and 240-262 663951003593 HMMPfam hit to PF00005, ABC_tran, score 2e-39 663951003594 PS00017 ATP/GTP-binding site motif A (P-loop). 663951003595 Transcriptional regulators [Transcription]; Region: MarR; COG1846 663951003596 MarR family; Region: MarR; pfam01047 663951003597 HMMPfam hit to PF01047, MarR, score 4.7e-20 663951003598 Putative GTPases (G3E family) [General function prediction only]; Region: COG0523 663951003599 CobW/HypB/UreG, nucleotide-binding domain; Region: cobW; pfam02492 663951003600 Cobalamin synthesis protein cobW C-terminal domain; Region: CobW_C; smart00833 663951003601 HMMPfam hit to PF02492, cobW, score 1.2e-62 663951003602 PS00017 ATP/GTP-binding site motif A (P-loop). 663951003603 HMMPfam hit to PF07683, CobW_C, score 8.5e-22 663951003604 Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660 663951003605 Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248 663951003606 active site 663951003607 catalytic tetrad [active] 663951003608 HMMPfam hit to PF00248, Aldo_ket_red, score 1e-36 663951003609 3 probable transmembrane helices predicted for SATW20_07640 by TMHMM2.0 at aa 17-36, 41-62 and 69-91 663951003610 Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Region: CitT; COG0471 663951003611 Anion permease ArsB/NhaD. These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life. A typical anion permease contains 8-13 transmembrane helices...; Region: ArsB_NhaD_permease; cl17221 663951003612 transmembrane helices; other site 663951003613 HMMPfam hit to PF00939, Na_sulph_symp, score 2.5e-108 663951003614 12 probable transmembrane helices predicted for SATW20_07650 by TMHMM2.0 at aa 25-42, 46-65, 70-92,122-144, 169-191, 257-279, 329-348, 363-382, 395-417,421-443, 450-472 and 492-514 663951003615 Deoxyribodipyrimidine photolyase [DNA replication, recombination, and repair]; Region: PhrB; COG0415 663951003616 DNA photolyase; Region: DNA_photolyase; pfam00875 663951003617 HMMPfam hit to PF03441, FAD_binding_7, score 3.5e-82 663951003618 3 probable transmembrane helices predicted for SATW20_07670 by TMHMM2.0 at aa 5-24, 28-47 and 68-90 663951003619 Predicted membrane protein [Function unknown]; Region: COG4330 663951003620 6 probable transmembrane helices predicted for SATW20_07680 by TMHMM2.0 at aa 5-22, 26-48, 60-82, 102-124,131-153 and 176-198 663951003621 HMMPfam hit to PF07099, DUF1361, score 1.4e-91 663951003622 Domain of unknown function found in archaea, bacteria, and plants; Region: DUF296; cd11378 663951003623 trimer interface [polypeptide binding]; other site 663951003624 putative Zn binding site [ion binding]; other site 663951003625 HMMPfam hit to PF03479, DUF296, score 2e-39 663951003626 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 663951003627 Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814 663951003628 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 663951003629 putative substrate translocation pore; other site 663951003630 12 probable transmembrane helices predicted for SATW20_07700 by TMHMM2.0 at aa 7-29, 40-62, 69-91, 95-117,129-151, 156-178, 203-225, 240-259, 266-288, 292-314,327-349 and 353-375 663951003631 HMMPfam hit to PF07690, MFS_1, score 9e-63 663951003632 1 probable transmembrane helix predicted for SATW20_07710 by TMHMM2.0 at aa 10-32 663951003633 This CD includes cysteinyl-tRNA(Pro) deacylases from Haemophilus influenzae and Escherichia coli and other related bacterial proteins. These trans-acting, single-domain proteins are homologs of ProX and also the cis-acting prolyl-tRNA synthetase (ProRS)...; Region: YbaK_deacylase; cd00002 663951003634 putative deacylase active site [active] 663951003635 HMMPfam hit to PF04073, YbaK, score 2.8e-60 663951003636 Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349 663951003637 helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420 663951003638 DeoR C terminal sensor domain; Region: DeoRC; pfam00455 663951003639 HMMPfam hit to PF08220, HTH_DeoR, score 8.1e-17 663951003640 PS00894 Bacterial regulatory proteins, deoR family signature. 663951003641 Predicted helix-turn-helix motif with score 1665.000, SD 4.86 at aa 21-42, sequence LTLQELIDRTGCSASTIRRDLS 663951003642 HMMPfam hit to PF00455, DeoR, score 9.4e-44 663951003643 Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB) [Carbohydrate transport and metabolism]; Region: FruK; COG1105 663951003644 1-phosphofructokinase (FruK), minor 6-phosphofructokinase (pfkB) and related sugar kinases. FruK plays an important role in the predominant pathway for fructose utilisation.This group also contains tagatose-6-phophate kinase, an enzyme of the tagatose...; Region: FruK_PfkB_like; cd01164 663951003645 putative substrate binding site [chemical binding]; other site 663951003646 putative ATP binding site [chemical binding]; other site 663951003647 HMMPfam hit to PF00294, PfkB, score 1.1e-52 663951003648 PS00584 pfkB family of carbohydrate kinases signature 2. 663951003649 PTS system 2-O-a-mannosyl-D-glycerate specific transporter subunit IIABC; Provisional; Region: PRK09765 663951003650 PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211 663951003651 active site 663951003652 phosphorylation site [posttranslational modification] 663951003653 PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569 663951003654 active site 663951003655 P-loop; other site 663951003656 phosphorylation site [posttranslational modification] 663951003657 Phosphotransferase system, fructose-specific IIC component [Carbohydrate transport and metabolism]; Region: FruA; COG1299 663951003658 HMMPfam hit to PF00359, PTS_EIIA_2, score 5.5e-27 663951003659 PS00372 PTS EIIA domains phosphorylation site signature 2. 663951003660 HMMPfam hit to PF02379, PTS_IIB_fruc, score 1.1e-57 663951003661 HMMPfam hit to PF02378, PTS_EIIC, score 1.6e-12 663951003662 9 probable transmembrane helices predicted for SATW20_07750 by TMHMM2.0 at aa 314-336, 356-378, 391-413,433-455, 467-489, 512-534, 547-569, 584-606 and 613-635 663951003663 N-acetylglucosamine-6-phosphate deacetylase, NagA, catalyzes the hydrolysis of the N-acetyl group of N-acetyl-glucosamine-6-phosphate (GlcNAc-6-P) to glucosamine 6-phosphate and acetate. This is the first committed step in the biosynthetic pathway to...; Region: NagA; cd00854 663951003664 N-acetylglucosamine-6-phosphate deacetylase [Carbohydrate transport and metabolism]; Region: NagA; COG1820 663951003665 active site 663951003666 dimer interface [polypeptide binding]; other site 663951003667 HMMPfam hit to PF01979, Amidohydro_1, score 9.3e-17 663951003668 Domain of unknown function DUF21; Region: DUF21; pfam01595 663951003669 Hemolysins and related proteins containing CBS domains [General function prediction only]; Region: TlyC; COG1253 663951003670 This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590 663951003671 Transporter associated domain; Region: CorC_HlyC; pfam03471 663951003672 HMMPfam hit to PF01595, DUF21, score 9.7e-89 663951003673 4 probable transmembrane helices predicted for SATW20_07770 by TMHMM2.0 at aa 4-22, 50-72, 92-114 and 131-153 663951003674 HMMPfam hit to PF00571, CBS, score 4e-25 663951003675 HMMPfam hit to PF03471, CorC_HlyC, score 2.9e-23 663951003676 Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660 663951003677 Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248 663951003678 active site 663951003679 catalytic tetrad [active] 663951003680 HMMPfam hit to PF00248, Aldo_ket_red, score 4.1e-121 663951003681 PS00798 Aldo/keto reductase family signature 1. 663951003682 PS00062 Aldo/keto reductase family signature 2. 663951003683 PS00063 Aldo/keto reductase family putative active site signature. 663951003684 undecaprenyl phosphate 4-deoxy-4-formamido-L-arabinose transferase; Provisional; Region: PRK10714 663951003685 Bacterial DPM1_like enzymes are related to eukaryotic DPM1; Region: DPM1_like_bac; cd04187 663951003686 Ligand binding site; other site 663951003687 Putative Catalytic site; other site 663951003688 DXD motif; other site 663951003689 HMMPfam hit to PF00535, Glycos_transf_2, score 6.3e-26 663951003690 2 probable transmembrane helices predicted for SATW20_07790 by TMHMM2.0 at aa 237-259 and 269-291 663951003691 Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642 663951003692 Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082 663951003693 dimer interface [polypeptide binding]; other site 663951003694 phosphorylation site [posttranslational modification] 663951003695 Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075 663951003696 ATP binding site [chemical binding]; other site 663951003697 Mg2+ binding site [ion binding]; other site 663951003698 G-X-G motif; other site 663951003699 HMMPfam hit to PF02518, HATPase_c, score 2.7e-34 663951003700 HMMPfam hit to PF00512, HisKA, score 2.4e-13 663951003701 HMMPfam hit to PF00672, HAMP, score 1e-06 663951003702 2 probable transmembrane helices predicted for SATW20_07800 by TMHMM2.0 at aa 9-31 and 41-63 663951003703 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 663951003704 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745 663951003705 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 663951003706 active site 663951003707 phosphorylation site [posttranslational modification] 663951003708 intermolecular recognition site; other site 663951003709 dimerization interface [polypeptide binding]; other site 663951003710 Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383 663951003711 DNA binding site [nucleotide binding] 663951003712 HMMPfam hit to PF00486, Trans_reg_C, score 3e-20 663951003713 HMMPfam hit to PF00072, Response_reg, score 7e-37 663951003714 DoxX; Region: DoxX; pfam07681 663951003715 3 probable transmembrane helices predicted for SATW20_07820 by TMHMM2.0 at aa 5-24, 75-97 and 99-121 663951003716 HMMPfam hit to PF07681, DoxX, score 0.00067 663951003717 Electron transfer DM13; Region: DM13; pfam10517 663951003718 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 663951003719 6 probable transmembrane helices predicted for SATW20_07840 by TMHMM2.0 at aa 4-21, 28-48, 53-72, 85-102,112-134 and 155-188 663951003720 7-cyano-7-deazaguanosine (preQ0) biosynthesis protein QueE; Region: Bsubt_queE; TIGR03365 663951003721 putative 7-cyano-7-deazaguanosine (preQ0) biosynthesis protein QueE; Region: rSAM_QueE_Ecoli; TIGR04322 663951003722 HMMPfam hit to PF04055, Radical_SAM, score 1.2e-09 663951003723 6-pyruvoyl-tetrahydropterin synthase [Coenzyme metabolism]; Region: COG0720 663951003724 active site 663951003725 HMMPfam hit to PF01242, PTPS, score 2.7e-08 663951003726 tRNA(Ile)-lysidine synthase MesJ [Cell cycle control, cell division, chromosome partitioning]; Region: MesJ; COG0037 663951003727 ExsB is a transcription regulator related protein. It is a subfamily of a Adenosine nucleotide binding superfamily of proteins. This protein family is represented by a single member in nearly every completed large (> 1000 genes) prokaryotic genome. In...; Region: ExsB; cd01995 663951003728 Ligand Binding Site [chemical binding]; other site 663951003729 HMMPfam hit to PF06508, ExsB, score 1.2e-114 663951003730 Type 1 glutamine amidotransferase (GATase1) domain found in Anthranilate synthase; Region: GATase1_Anthranilate_Synthase; cd01743 663951003731 Glutamine amidotransferase class-I; Region: GATase; pfam00117 663951003732 glutamine binding [chemical binding]; other site 663951003733 catalytic triad [active] 663951003734 HMMPfam hit to PF00117, GATase, score 5.1e-61 663951003735 PS00442 Glutamine amidotransferases class-I active site. 663951003736 aminodeoxychorismate synthase; Provisional; Region: PRK07508 663951003737 chorismate binding enzyme; Region: Chorismate_bind; cl10555 663951003738 HMMPfam hit to PF00425, Chorismate_bind, score 5.3e-54 663951003739 PS00017 ATP/GTP-binding site motif A (P-loop). 663951003740 Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase [Amino acid transport and metabolism / Coenzyme metabolism]; Region: IlvE; COG0115 663951003741 substrate-cofactor binding pocket; other site 663951003742 Aminotransferase class IV; Region: Aminotran_4; pfam01063 663951003743 pyridoxal 5'-phosphate binding site [chemical binding]; other site 663951003744 catalytic residue [active] 663951003745 2 probable transmembrane helices predicted for SATW20_07910 by TMHMM2.0 at aa 2-19 and 29-51 663951003746 Allophanate hydrolase subunit 1; Region: AHS1; smart00796 663951003747 Allophanate hydrolase subunit 1 [Amino acid transport and metabolism]; Region: DUR1; COG2049 663951003748 HMMPfam hit to PF02682, AHS1, score 5.7e-26 663951003749 Allophanate hydrolase subunit 2 [Amino acid transport and metabolism]; Region: DUR1; COG1984 663951003750 HMMPfam hit to PF02626, AHS2, score 5.2e-43 663951003751 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily [Cell envelope biogenesis, outer membrane]; Region: MdoB; COG1368 663951003752 Sulfatase; Region: Sulfatase; pfam00884 663951003753 5 probable transmembrane helices predicted for SATW20_07940 by TMHMM2.0 at aa 9-31, 41-63, 70-92, 122-141 and 154-173 663951003754 HMMPfam hit to PF00884, Sulfatase, score 5.7e-39 663951003755 ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only]; Region: Uup; COG0488 663951003756 ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221 663951003757 ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221 663951003758 ABC transporter; Region: ABC_tran_2; pfam12848 663951003759 ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221 663951003760 HMMPfam hit to PF00005, ABC_tran, score 3.9e-42 663951003761 PS00017 ATP/GTP-binding site motif A (P-loop). 663951003762 PS00211 ABC transporters family signature. 663951003763 HMMPfam hit to PF00005, ABC_tran, score 3.7e-46 663951003764 PS00017 ATP/GTP-binding site motif A (P-loop). 663951003765 ATP-dependent DNA helicase RecQ; Region: recQ; TIGR01389 663951003766 DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046 663951003767 ATP binding site [chemical binding]; other site 663951003768 putative Mg++ binding site [ion binding]; other site 663951003769 Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079 663951003770 nucleotide binding region [chemical binding]; other site 663951003771 ATP-binding site [chemical binding]; other site 663951003772 This DNA-binding domain is found in the RecQ helicase among others and has a helix-turn-helix structure; Region: RQC; smart00956 663951003773 HRDC domain; Region: HRDC; pfam00570 663951003774 HMMPfam hit to PF00270, DEAD, score 3.6e-34 663951003775 HMMPfam hit to PF00271, Helicase_C, score 5.9e-30 663951003776 HMMPfam hit to PF00570, HRDC, score 3e-10 663951003777 ABC-type proline/glycine betaine transport systems, ATPase components [Amino acid transport and metabolism]; Region: OpuBA; COG1125 663951003778 ATP-binding cassette domain of the osmoprotectant transporter; Region: ABC_OpuCA_Osmoprotection; cd03295 663951003779 Walker A/P-loop; other site 663951003780 ATP binding site [chemical binding]; other site 663951003781 Q-loop/lid; other site 663951003782 ABC transporter signature motif; other site 663951003783 Walker B; other site 663951003784 D-loop; other site 663951003785 H-loop/switch region; other site 663951003786 HMMPfam hit to PF00005, ABC_tran, score 6.3e-56 663951003787 PS00017 ATP/GTP-binding site motif A (P-loop). 663951003788 PS00211 ABC transporters family signature. 663951003789 ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism]; Region: TauC; COG0600 663951003790 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 663951003791 dimer interface [polypeptide binding]; other site 663951003792 conserved gate region; other site 663951003793 ABC-ATPase subunit interface; other site 663951003794 ABC-type proline/glycine betaine transport systems, periplasmic components [Amino acid transport and metabolism]; Region: ProX; cl17891 663951003795 Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein) [Cell envelope biogenesis, outer membrane]; Region: OpuBC; COG1732 663951003796 HMMPfam hit to PF00528, BPD_transp_1, score 1.4e-29 663951003797 6 probable transmembrane helices predicted for SATW20_07980 by TMHMM2.0 at aa 23-45, 52-74, 78-97,148-170, 180-202 and 209-231 663951003798 PS00402 Binding-protein-dependent transport systems inner membrane comp. sign. 663951003799 HMMPfam hit to PF04069, OpuAC, score 1.7e-84 663951003800 histidinol-phosphate aminotransferase; Provisional; Region: PRK03158 663951003801 Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609 663951003802 pyridoxal 5'-phosphate binding site [chemical binding]; other site 663951003803 homodimer interface [polypeptide binding]; other site 663951003804 catalytic residue [active] 663951003805 HMMPfam hit to PF00155, Aminotran_1_2, score 3.4e-49 663951003806 PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 663951003807 5'(3')-deoxyribonucleotidase [Nucleotide transport and metabolism]; Region: COG4502 663951003808 HMMPfam hit to PF06941, NT5C, score 1.8e-05 663951003809 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase [Lipid metabolism / General function prediction only]; Region: LCB5; COG1597 663951003810 Diacylglycerol kinase catalytic domain; Region: DAGK_cat; pfam00781 663951003811 HMMPfam hit to PF00781, DAGK_cat, score 1.5e-28 663951003812 Dipeptide/tripeptide permease [Amino acid transport and metabolism]; Region: PTR2; COG3104 663951003813 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 663951003814 putative substrate translocation pore; other site 663951003815 POT family; Region: PTR2; cl17359 663951003816 13 probable transmembrane helices predicted for SATW20_08020 by TMHMM2.0 at aa 40-62, 69-88, 103-136,157-176, 186-208, 231-253, 263-280, 293-310, 341-363,376-398, 408-430, 443-462 and 472-494 663951003817 HMMPfam hit to PF00854, PTR2, score 4.3e-34 663951003818 PS01023 PTR2 family proton/oligopeptide symporters signature 2. 663951003819 Enzyme related to GTP cyclohydrolase I [General function prediction only]; Region: COG0780 663951003820 HMMPfam hit to PF01227, GTP_cyclohydroI, score 1.8e-55 663951003821 Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697 663951003822 HMMPfam hit to PF00892, DUF6, score 4.9e-09 663951003823 10 probable transmembrane helices predicted for SATW20_08040 by TMHMM2.0 at aa 7-29, 39-56, 68-87, 97-114,121-136, 146-168, 175-197, 207-229, 236-254 and 259-276 663951003824 HMMPfam hit to PF00892, DUF6, score 2.9e-09 663951003825 Protein involved in ribonucleotide reduction [Nucleotide transport and metabolism]; Region: NrdI; COG1780 663951003826 HMMPfam hit to PF07972, Flavodoxin_NdrI, score 8.9e-63 663951003827 ribonucleotide-diphosphate reductase subunit alpha; Validated; Region: PRK07632 663951003828 Ribonucleotide reductase N-terminal; Region: RNR_N; pfam08343 663951003829 Class I ribonucleotide reductase; Region: RNR_I; cd01679 663951003830 active site 663951003831 dimer interface [polypeptide binding]; other site 663951003832 catalytic residues [active] 663951003833 effector binding site; other site 663951003834 R2 peptide binding site; other site 663951003835 HMMPfam hit to PF08343, RNR_N, score 1.5e-35 663951003836 HMMPfam hit to PF00317, Ribonuc_red_lgN, score 1.9e-25 663951003837 HMMPfam hit to PF02867, Ribonuc_red_lgC, score 7.7e-114 663951003838 PS00089 Ribonucleotide reductase large subunit signature. 663951003839 ribonucleotide-diphosphate reductase subunit beta; Provisional; Region: nrdF2; PRK13966 663951003840 Ribonucleotide Reductase, R2/beta subunit, ferritin-like diiron-binding domain; Region: RNRR2; cd01049 663951003841 dimer interface [polypeptide binding]; other site 663951003842 putative radical transfer pathway; other site 663951003843 diiron center [ion binding]; other site 663951003844 tyrosyl radical; other site 663951003845 HMMPfam hit to PF00268, Ribonuc_red_sm, score 1.3e-19 663951003846 1 probable transmembrane helix predicted for SATW20_08070 by TMHMM2.0 at aa 155-177 663951003847 Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550 663951003848 ABC-ATPase subunit interface; other site 663951003849 dimer interface [polypeptide binding]; other site 663951003850 putative PBP binding regions; other site 663951003851 8 probable transmembrane helices predicted for SATW20_08080 by TMHMM2.0 at aa 7-29, 49-71, 92-124,137-159, 184-206, 226-248, 268-290 and 295-314 663951003852 HMMPfam hit to PF01032, FecCD, score 2e-36 663951003853 Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550 663951003854 ABC-ATPase subunit interface; other site 663951003855 dimer interface [polypeptide binding]; other site 663951003856 putative PBP binding regions; other site 663951003857 9 probable transmembrane helices predicted for SATW20_08090 by TMHMM2.0 at aa 10-32, 44-63, 73-95,102-124, 129-148, 179-201, 224-246, 266-285 and 295-312 663951003858 HMMPfam hit to PF01032, FecCD, score 6.4e-40 663951003859 ABC-type enterochelin transport system, ATPase component [Inorganic ion transport and metabolism]; Region: CeuD; COG4604 663951003860 ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214 663951003861 Walker A/P-loop; other site 663951003862 ATP binding site [chemical binding]; other site 663951003863 Q-loop/lid; other site 663951003864 ABC transporter signature motif; other site 663951003865 Walker B; other site 663951003866 D-loop; other site 663951003867 H-loop/switch region; other site 663951003868 HMMPfam hit to PF00005, ABC_tran, score 9.7e-48 663951003869 PS00017 ATP/GTP-binding site motif A (P-loop). 663951003870 ABC-type enterochelin transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: CeuA; COG4607 663951003871 Siderophore binding protein FatB. These proteins have been shown to function as ABC-type initial receptors in the siderophore-mediated iron uptake in some eubacterial species. They belong to the TroA superfamily of periplasmic metal binding proteins...; Region: FatB; cd01140 663951003872 putative ligand binding residues [chemical binding]; other site 663951003873 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 663951003874 HMMPfam hit to PF01497, Peripla_BP_2, score 3e-40 663951003875 PS00017 ATP/GTP-binding site motif A (P-loop). 663951003876 Zinc finger domain containing protein (CHY type) [Function unknown]; Region: COG4357 663951003877 CHY zinc finger; Region: zf-CHY; pfam05495 663951003878 HMMPfam hit to PF05495, zf-CHY, score 1.6e-37 663951003879 PS00190 Cytochrome c family heme-binding site signature. 663951003880 UDP-N-acetylenolpyruvoylglucosamine reductase; Provisional; Region: murB; PRK13906 663951003881 FAD binding domain; Region: FAD_binding_4; pfam01565 663951003882 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain; Region: MurB_C; pfam02873 663951003883 HMMPfam hit to PF02873, MurB_C, score 5.9e-37 663951003884 HMMPfam hit to PF01565, FAD_binding_4, score 9.6e-32 663951003885 Uncharacterized protein family (UPF0157); Region: UPF0157; pfam04229 663951003886 HMMPfam hit to PF04229, UPF0157, score 3.2e-77 663951003887 1 probable transmembrane helix predicted for SATW20_08150 by TMHMM2.0 at aa 4-21 663951003888 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 663951003889 Protein of unknown function (DUF2847); Region: DUF2847; pfam11009 663951003890 Glycerate kinase [Carbohydrate transport and metabolism]; Region: COG1929 663951003891 HMMPfam hit to PF02595, Gly_kinase, score 7.5e-09 663951003892 peptidase T; Region: peptidase-T; TIGR01882 663951003893 M20 Peptidase T specifically cleaves tripeptides; Region: M20_peptT; cd03892 663951003894 metal binding site [ion binding]; metal-binding site 663951003895 dimer interface [polypeptide binding]; other site 663951003896 HMMPfam hit to PF01546, Peptidase_M20, score 1.4e-12 663951003897 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 663951003898 HMMPfam hit to PF07687, M20_dimer, score 1e-24 663951003899 PS00759 ArgE / dapE / ACY1 / CPG2 / yscS family signature 2. 663951003900 PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 663951003901 Uncharacterized conserved protein [Function unknown]; Region: COG3610 663951003902 3 probable transmembrane helices predicted for SATW20_08190 by TMHMM2.0 at aa 15-32, 45-64 and 84-106 663951003903 Uncharacterized conserved protein [Function unknown]; Region: COG2966 663951003904 Protein of unknown function (DUF1212); Region: DUF1212; pfam06738 663951003905 Protein of unknown function (DUF3815); Region: DUF3815; cl01118 663951003906 5 probable transmembrane helices predicted for SATW20_08200 by TMHMM2.0 at aa 120-142, 146-163, 170-188,198-217 and 230-252 663951003907 HMMPfam hit to PF06738, DUF1212, score 2.2e-85 663951003908 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 663951003909 5TMR of 5TMR-LYT; Region: 5TM-5TMR_LYT; pfam07694 663951003910 c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal transduction mechanisms]; Region: COG2199 663951003911 Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949 663951003912 metal binding site [ion binding]; metal-binding site 663951003913 active site 663951003914 I-site; other site 663951003915 HMMPfam hit to PF00990, GGDEF, score 4.6e-33 663951003916 6 probable transmembrane helices predicted for SATW20_08210 by TMHMM2.0 at aa 5-24, 31-53, 68-90, 97-119,124-146 and 153-175 663951003917 HMMPfam hit to PF07694, 5TM-5TMR_LYT, score 2.3e-21 663951003918 phospho-N-acetylmuramoyl-pentapeptide-transferase; Region: mraY; TIGR00445 663951003919 This subfamily contains Escherichia coli WecA, Bacillus subtilis TagO and related proteins. WecA is an UDP-N-acetylglucosamine (GlcNAc):undecaprenyl-phosphate (Und-P) GlcNAc-1-phosphate transferase that catalyzes the formation of a phosphodiester bond...; Region: GT_WecA_like; cd06853 663951003920 Mg++ binding site [ion binding]; other site 663951003921 putative catalytic motif [active] 663951003922 substrate binding site [chemical binding]; other site 663951003923 10 probable transmembrane helices predicted for SATW20_08220 by TMHMM2.0 at aa 2-24, 44-63, 70-89, 99-121,128-150, 165-197, 204-226, 231-253, 285-304 and 309-331 663951003924 HMMPfam hit to PF00953, Glycos_transf_4, score 3.2e-65 663951003925 Uncharacterized conserved protein [Function unknown]; Region: COG1739 663951003926 Uncharacterized protein family UPF0029; Region: UPF0029; pfam01205 663951003927 Domain of unknown function (DUF1949); Region: DUF1949; pfam09186 663951003928 HMMPfam hit to PF09186, DUF1949, score 5.5e-16 663951003929 HMMPfam hit to PF01205, UPF0029, score 7.7e-58 663951003930 PS00910 Uncharacterized protein family UPF0029 signature. 663951003931 EDD domain protein, DegV family; Region: DegV; TIGR00762 663951003932 Uncharacterized protein, DegV family COG1307; Region: DegV; pfam02645 663951003933 HMMPfam hit to PF02645, DegV, score 8.2e-82 663951003934 DEAD-like helicases superfamily; Region: DEXDc; smart00487 663951003935 DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046 663951003936 ATP binding site [chemical binding]; other site 663951003937 putative Mg++ binding site [ion binding]; other site 663951003938 Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079 663951003939 nucleotide binding region [chemical binding]; other site 663951003940 ATP-binding site [chemical binding]; other site 663951003941 HMMPfam hit to PF04851, ResIII, score 1.3e-06 663951003942 PS00017 ATP/GTP-binding site motif A (P-loop). 663951003943 HMMPfam hit to PF00271, Helicase_C, score 1.2e-09 663951003944 Predicted amidophosphoribosyltransferases [General function prediction only]; Region: ComFC; COG1040 663951003945 Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223 663951003946 active site 663951003947 RaiA ("ribosome-associated inhibitor A", also known as Protein Y (PY), YfiA, and SpotY, is a stress-response protein that binds the ribosomal subunit interface and arrests translation by interfering with aminoacyl-tRNA binding to the ribosomal...; Region: RaiA; cd00552 663951003948 30S subunit binding site; other site 663951003949 HMMPfam hit to PF02482, Ribosomal_S30AE, score 1.7e-26 663951003950 preprotein translocase subunit SecA; Reviewed; Region: PRK12904 663951003951 SecA preprotein cross-linking domain; Region: SecA_PP_bind; pfam01043 663951003952 Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cl17351 663951003953 nucleotide binding region [chemical binding]; other site 663951003954 ATP-binding site [chemical binding]; other site 663951003955 SEC-C motif; Region: SEC-C; pfam02810 663951003956 HMMPfam hit to PF07517, SecA_DEAD, score 4.5e-193 663951003957 HMMPfam hit to PF01043, SecA_PP_bind, score 3.3e-73 663951003958 HMMPfam hit to PF00271, Helicase_C, score 0.00091 663951003959 PS01312 Protein secA signatures. 663951003960 HMMPfam hit to PF07516, SecA_SW, score 2e-109 663951003961 HMMPfam hit to PF02810, SEC-C, score 1e-05 663951003962 peptide chain release factor 2; Validated; Region: prfB; PRK00578 663951003963 This domain is found in peptide chain release factors; Region: PCRF; smart00937 663951003964 RF-1 domain; Region: RF-1; pfam00472 663951003965 HMMPfam hit to PF03462, PCRF, score 3e-65 663951003966 HMMPfam hit to PF00472, RF-1, score 3.1e-68 663951003967 FOG: LysM repeat [Cell envelope biogenesis, outer membrane]; Region: LytE; COG1388 663951003968 Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118 663951003969 Surface antigen [General function prediction only]; Region: COG3942 663951003970 CHAP domain; Region: CHAP; pfam05257 663951003971 HMMPfam hit to PF01476, LysM, score 4.1e-09 663951003972 HMMPfam hit to PF05257, CHAP, score 1.9e-47 663951003973 HD domain; Region: HD_3; cl17350 663951003974 HMMPfam hit to PF01966, HD, score 0.00039 663951003975 Uncharacterized protein conserved in bacteria [Function unknown]; Region: CsbA; COG4897 663951003976 3 probable transmembrane helices predicted for SATW20_08320 by TMHMM2.0 at aa 2-21, 26-41 and 48-65 663951003977 excinuclease ABC subunit B; Provisional; Region: PRK05298 663951003978 DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046 663951003979 ATP binding site [chemical binding]; other site 663951003980 Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079 663951003981 nucleotide binding region [chemical binding]; other site 663951003982 ATP-binding site [chemical binding]; other site 663951003983 Ultra-violet resistance protein B; Region: UvrB; pfam12344 663951003984 UvrB/uvrC motif; Region: UVR; pfam02151 663951003985 HMMPfam hit to PF04851, ResIII, score 1.2e-13 663951003986 PS00017 ATP/GTP-binding site motif A (P-loop). 663951003987 HMMPfam hit to PF00271, Helicase_C, score 7.5e-22 663951003988 HMMPfam hit to PF02151, UVR, score 3.8e-11 663951003989 excinuclease ABC subunit A; Reviewed; Region: uvrA; PRK00349 663951003990 ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270 663951003991 ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270 663951003992 ATP-binding cassette domain II of the excision repair protein UvrA; Region: ABC_UvrA_II; cd03271 663951003993 PS00017 ATP/GTP-binding site motif A (P-loop). 663951003994 PS00190 Cytochrome c family heme-binding site signature. 663951003995 PS00211 ABC transporters family signature. 663951003996 HMMPfam hit to PF00005, ABC_tran, score 2.7e-24 663951003997 PS00017 ATP/GTP-binding site motif A (P-loop). 663951003998 PS00211 ABC transporters family signature. 663951003999 HPr kinase/phosphorylase; Provisional; Region: PRK05428 663951004000 HPr Serine kinase N terminus; Region: Hpr_kinase_N; pfam02603 663951004001 HprK/P, the bifunctional histidine-containing protein kinase/phosphatase, controls the phosphorylation state of the phosphocarrier protein HPr and regulates the utilization of carbon sources by gram-positive bacteria. It catalyzes both the ATP-dependent...; Region: HprK_C; cd01918 663951004002 Hpr binding site; other site 663951004003 active site 663951004004 homohexamer subunit interaction site [polypeptide binding]; other site 663951004005 HMMPfam hit to PF02603, Hpr_kinase_N, score 3.3e-39 663951004006 HMMPfam hit to PF07475, Hpr_kinase_C, score 9.5e-98 663951004007 PS00017 ATP/GTP-binding site motif A (P-loop). 663951004008 Predicted helix-turn-helix motif with score 1413.000, SD 4.00 at aa 233-254, sequence WNKQKLYDRVGLNEETLSILDT 663951004009 prolipoprotein diacylglyceryl transferase; Reviewed; Region: PRK12437 663951004010 HMMPfam hit to PF01790, LGT, score 5.7e-131 663951004011 5 probable transmembrane helices predicted for SATW20_08360 by TMHMM2.0 at aa 20-42, 55-74, 89-111,203-221 and 236-255 663951004012 PS01311 Prolipoprotein diacylglyceryl transferase signature. 663951004013 putative acyl transferase; Provisional; Region: PRK10191 663951004014 Maltose O-acyltransferase (MAT)-like: This family is composed of maltose O-acetyltransferase, galactoside O-acetyltransferase (GAT), xenobiotic acyltransferase (XAT) and similar proteins. MAT and GAT catalyze the CoA-dependent acetylation of the...; Region: LbH_MAT_like; cd04647 663951004015 trimer interface [polypeptide binding]; other site 663951004016 active site 663951004017 substrate binding site [chemical binding]; other site 663951004018 CoA binding site [chemical binding]; other site 663951004019 HMMPfam hit to PF00132, Hexapep, score 12 663951004020 HMMPfam hit to PF00132, Hexapep, score 0.044 663951004021 PS00101 Hexapeptide-repeat containing-transferases signature. 663951004022 HMMPfam hit to PF00132, Hexapep, score 0.7 663951004023 Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429 663951004024 binding surface 663951004025 TPR motif; other site 663951004026 Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189 663951004027 TPR motif; other site 663951004028 binding surface 663951004029 HMMPfam hit to PF07719, TPR_2, score 7.6e-05 663951004030 HMMPfam hit to PF07719, TPR_2, score 0.0013 663951004031 Predicted helix-turn-helix motif with score 976.000,SD 2.51 at aa 453-474, sequence VTKKQITTWLGITQYKLNKMIE 663951004032 thioredoxin-disulfide reductase; Region: TRX_reduct; TIGR01292 663951004033 NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500 663951004034 Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070 663951004035 HMMPfam hit to PF07992, Pyr_redox_2, score 6.6e-52 663951004036 PS00573 Pyridine nucleotide-disulphide oxidoreductases class-II active site. 663951004037 HMMPfam hit to PF00070, Pyr_redox, score 2.9e-33 663951004038 Predicted P-loop-containing kinase [General function prediction only]; Region: COG1660 663951004039 HMMPfam hit to PF03668, ATP_bind_2, score 4.5e-131 663951004040 PS00017 ATP/GTP-binding site motif A (P-loop). 663951004041 PS00017 ATP/GTP-binding site motif A (P-loop). 663951004042 conserved hypothetical protein, cofD-related; Region: CofD_related; TIGR01826 663951004043 Family of CofD-like proteins and proteins related to YvcK; Region: CofD_YvcK; cd07044 663951004044 phosphate binding site [ion binding]; other site 663951004045 dimer interface [polypeptide binding]; other site 663951004046 HMMPfam hit to PF01933, UPF0052, score 5.3e-159 663951004047 Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1481 663951004048 Sporulation Regulator WhiA N terminal; Region: WhiA_N; pfam10298 663951004049 HMMPfam hit to PF02650, DUF199, score 2.9e-126 663951004050 Clp protease; Region: CLP_protease; pfam00574 663951004051 Caseinolytic protease (ClpP) is an ATP-dependent, highly conserved serine protease; Region: S14_ClpP_2; cd07017 663951004052 oligomer interface [polypeptide binding]; other site 663951004053 active site residues [active] 663951004054 HMMPfam hit to PF00574, CLP_protease, score 1.9e-139 663951004055 PS00381 Endopeptidase Clp serine active site. 663951004056 PS00382 Endopeptidase Clp histidine active site. 663951004057 Predicted nucleoside-diphosphate sugar epimerase [General function prediction only]; Region: COG1090 663951004058 Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931 663951004059 NAD(P) binding site [chemical binding]; other site 663951004060 active site 663951004061 HMMPfam hit to PF08338, DUF1731, score 2.3e-21 663951004062 HMMPfam hit to PF01370, Epimerase, score 4.9e-08 663951004063 1 probable transmembrane helix predicted for SATW20_08450 by TMHMM2.0 at aa 25-47 663951004064 Transcriptional regulator, contains sigma factor-related N-terminal domain [Transcription]; Region: DeoR; COG2390 663951004065 Putative sugar-binding domain; Region: Sugar-bind; pfam04198 663951004066 HMMPfam hit to PF04198, Sugar-bind, score 2.6e-102 663951004067 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 663951004068 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Region: Gp_dh_N; smart00846 663951004069 glyceraldehyde-3-phosphate dehydrogenase, type I; Region: GAPDH-I; TIGR01534 663951004070 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; pfam02800 663951004071 HMMPfam hit to PF00044, Gp_dh_N, score 1.3e-87 663951004072 PS00071 Glyceraldehyde 3-phosphate dehydrogenase active site. 663951004073 HMMPfam hit to PF02800, Gp_dh_C, score 9.2e-99 663951004074 PS00211 ABC transporters family signature. 663951004075 Phosphoglycerate kinase (PGK) is a monomeric enzyme which catalyzes the transfer of the high-energy phosphate group of 1,3-bisphosphoglycerate to ADP, forming ATP and 3-phosphoglycerate. This reaction represents the first of the two substrate-level...; Region: Phosphoglycerate_kinase; cd00318 663951004076 Phosphoglycerate kinase; Region: PGK; pfam00162 663951004077 substrate binding site [chemical binding]; other site 663951004078 hinge regions; other site 663951004079 ADP binding site [chemical binding]; other site 663951004080 catalytic site [active] 663951004081 HMMPfam hit to PF00162, PGK, score 1.2e-186 663951004082 PS00111 Phosphoglycerate kinase signature. 663951004083 Triosephosphate isomerase (TIM) is a glycolytic enzyme that catalyzes the interconversion of dihydroxyacetone phosphate and D-glyceraldehyde-3-phosphate. The reaction is very efficient and requires neither cofactors nor metal ions. TIM, usually...; Region: TIM; cd00311 663951004084 triosephosphate isomerase; Provisional; Region: PRK14565 663951004085 substrate binding site [chemical binding]; other site 663951004086 dimer interface [polypeptide binding]; other site 663951004087 catalytic triad [active] 663951004088 HMMPfam hit to PF00121, TIM, score 5.4e-130 663951004089 PS00171 Triosephosphate isomerase active site. 663951004090 Phosphoglyceromutase [Carbohydrate transport and metabolism]; Region: GpmI; COG0696 663951004091 phosphoglyceromutase; Provisional; Region: PRK05434 663951004092 HMMPfam hit to PF06415, iPGM_N, score 5.6e-245 663951004093 PS00687 Aldehyde dehydrogenases glutamic acid active site. 663951004094 HMMPfam hit to PF01676, Metalloenzyme, score 8.5e-53 663951004095 enolase; Provisional; Region: eno; PRK00077 663951004096 Enolase: Enolases are homodimeric enzymes that catalyse the reversible dehydration of 2-phospho-D-glycerate to phosphoenolpyruvate as part of the glycolytic and gluconeogenesis pathways. The reaction is facilitated by the presence of metal ions; Region: enolase; cd03313 663951004097 dimer interface [polypeptide binding]; other site 663951004098 metal binding site [ion binding]; metal-binding site 663951004099 substrate binding pocket [chemical binding]; other site 663951004100 HMMPfam hit to PF03952, Enolase_N, score 2.8e-72 663951004101 HMMPfam hit to PF00113, Enolase_C, score 4.5e-168 663951004102 PS00164 Enolase signature. 663951004103 4 probable transmembrane helices predicted for SATW20_08520 by TMHMM2.0 at aa 12-34, 59-81, 88-110 and 120-142 663951004104 Preprotein translocase subunit SecG [Intracellular trafficking and secretion]; Region: SecG; COG1314 663951004105 HMMPfam hit to PF03840, SecG, score 2.2e-24 663951004106 2 probable transmembrane helices predicted for SATW20_08530 by TMHMM2.0 at aa 5-22 and 53-75 663951004107 Esterase/lipase [General function prediction only]; Region: COG1647 663951004108 Baculovirus DNA helicase; Region: Baculo_helicase; pfam04735 663951004109 ribonuclease R; Region: RNase_R; TIGR02063 663951004110 Ribonuclease B OB domain; Region: OB_RNB; pfam08206 663951004111 Ribonuclease B OB domain; Region: OB_RNB; pfam08206 663951004112 RNB domain; Region: RNB; pfam00773 663951004113 S1_RNase_R: RNase R C-terminal S1 domain. RNase R is a processive 3' to 5' exoribonuclease, which is a homolog of RNase II. RNase R degrades RNA with secondary structure having a 3' overhang of at least 7 nucleotides. RNase R and PNPase...; Region: S1_RNase_R; cd04471 663951004114 RNA binding site [nucleotide binding]; other site 663951004115 HMMPfam hit to PF08206, OB_RNB, score 9.7e-22 663951004116 HMMPfam hit to PF08206, OB_RNB, score 2.8e-05 663951004117 HMMPfam hit to PF00773, RNB, score 3.4e-153 663951004118 PS01175 Ribonuclease II family signature. 663951004119 HMMPfam hit to PF00575, S1, score 2e-16 663951004120 Small protein B (SmpB) is a component of the trans-translation system in prokaryotes for releasing stalled ribosome from damaged messenger RNAs; Region: SmpB; cd09294 663951004121 SmpB-tmRNA interface; other site 663951004122 HMMPfam hit to PF01668, SmpB, score 4.6e-41 663951004123 PS01317 Protein smpB signature. 663951004124 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 663951004125 1 probable transmembrane helix predicted for SATW20_08600 by TMHMM2.0 at aa 7-29 663951004126 N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301 663951004127 Coenzyme A binding pocket [chemical binding]; other site 663951004128 HMMPfam hit to PF00583, Acetyltransf_1, score 1.3e-07 663951004129 YSIRK type signal peptide; Region: YSIRK_signal; pfam04650 663951004130 C-terminus of bacterial fibrinogen-binding adhesin; Region: SdrG_C_C; pfam10425 663951004131 LPXTG-motif cell wall anchor domain; Region: LPXTG_anchor; TIGR01167 663951004132 HMMPfam hit to PF04650, YSIRK_signal, score 7.2e-10 663951004133 1 probable transmembrane helix predicted for SATW20_08620 by TMHMM2.0 at aa 16-33 663951004134 PS00402 Binding-protein-dependent transport systems inner membrane comp. sign. 663951004135 HMMPfam hit to PF00746, Gram_pos_anchor, score 2.7e-05 663951004136 PS00343 Gram-positive cocci surface proteins 'anchoring' hexapeptide. 663951004137 Staphylococcus aureus coagulase; Region: Coagulase; pfam08764 663951004138 HMMPfam hit to PF08764, Coagulase, score 6.1e-08 663951004139 Staphylococcal nuclease homologues; Region: SNc; smart00318 663951004140 Staphylococcal nuclease homologues. SNase homologues are found in bacteria, archaea, and eukaryotes. They contain no disufide bonds; Region: SNc; cd00175 663951004141 Catalytic site; other site 663951004142 2 probable transmembrane helices predicted for SATW20_08660 by TMHMM2.0 at aa 5-27 and 37-59 663951004143 HMMPfam hit to PF00565, SNase, score 1.4e-65 663951004144 PS01123 Thermonuclease family signature 1. 663951004145 PS01284 Thermonuclease family signature 2. 663951004146 Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea. CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458 663951004147 DNA-binding site [nucleotide binding]; DNA binding site 663951004148 RNA-binding motif; other site 663951004149 HMMPfam hit to PF00313, CSD, score 1.9e-42 663951004150 PS00352 'Cold-shock' DNA-binding domain signature. 663951004151 Uncharacterized distant relative of cell wall-associated hydrolases [Function unknown]; Region: COG3863 663951004152 3 probable transmembrane helices predicted for SATW20_08710 by TMHMM2.0 at aa 4-26, 33-55 and 60-82 663951004153 Protein of unknown function (DUF1250); Region: DUF1250; pfam06855 663951004154 HMMPfam hit to PF06855, DUF1250, score 8.7e-30 663951004155 Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067 663951004156 catalytic core [active] 663951004157 HMMPfam hit to PF00300, PGAM, score 2.6e-31 663951004158 PS00175 Phosphoglycerate mutase family phosphohistidine signature. 663951004159 Lysine efflux permease [General function prediction only]; Region: COG1279 663951004160 HMMPfam hit to PF01810, LysE, score 1.7e-40 663951004161 6 probable transmembrane helices predicted for SATW20_08750 by TMHMM2.0 at aa 4-26, 38-60, 70-92, 112-134,144-165 and 178-197 663951004162 N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182 663951004163 Acetyltransferase (GNAT) domain; Region: Acetyltransf_4; pfam13420 663951004164 N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182 663951004165 peroxiredoxin, Ohr subfamily; Region: organ_hyd_perox; TIGR03561 663951004166 HMMPfam hit to PF02566, OsmC, score 1.6e-31 663951004167 3-dehydroquinate dehydratase [Amino acid transport and metabolism]; Region: AroD; COG0710 663951004168 Type I 3-dehydroquinase, (3-dehydroquinate dehydratase or DHQase); Region: DHQase_I; cd00502 663951004169 active site 663951004170 catalytic residue [active] 663951004171 dimer interface [polypeptide binding]; other site 663951004172 HMMPfam hit to PF01487, DHquinase_I, score 7.1e-45 663951004173 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 663951004174 Nitroreductase-like family which includes NADH oxidase and arsenite oxidiase. NADH oxidase catalyses the oxidation of NAD(P)H and accepts a wide broad range of compounds as electron acceptors, such as nitrocompound. Arsenite oxidase in a...; Region: Arsenite_oxidase; cd02135 663951004175 putative FMN binding site [chemical binding]; other site 663951004176 HMMPfam hit to PF00881, Nitroreductase, score 9e-07 663951004177 TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947 663951004178 catalytic residues [active] 663951004179 HMMPfam hit to PF00085, Thioredoxin, score 3e-07 663951004180 Arsenate Reductase (ArsC) family, unknown subfamily; uncharacterized proteins containing a CXXC motif with similarity to thioredoxin (TRX)-fold arsenic reductases, ArsC. Proteins containing a redox active CXXC motif like TRX and glutaredoxin (GRX)...; Region: ArsC_like; cd03036 663951004181 ArsC family; Region: ArsC; pfam03960 663951004182 putative ArsC-like catalytic residues; other site 663951004183 putative TRX-like catalytic residues [active] 663951004184 HMMPfam hit to PF03960, ArsC, score 1.6e-31 663951004185 Glycine cleavage H-protein. Glycine cleavage H-proteins are part of the glycine cleavage system (GCS) found in bacteria, archea and the mitochondria of eukaryotes. GCS is a multienzyme complex consisting of 4 different components (P-, H-, T- and...; Region: GCS_H; cd06848 663951004186 lipoyl attachment site [posttranslational modification]; other site 663951004187 HMMPfam hit to PF01597, GCV_H, score 4.4e-66 663951004188 Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3878 663951004189 HMMPfam hit to PF09234, DUF1963, score 5.5e-112 663951004190 TOPRIM_ RNase M5_like: The topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain found in Ribonuclease M5: (RNase M5) and other small primase-like proteins from bacteria and archaea. RNase M5 catalyzes the maturation of 5S rRNA in low...; Region: TOPRIM_RNase_M5_like; cd01027 663951004191 putative active site [active] 663951004192 putative metal binding site [ion binding]; other site 663951004193 HMMPfam hit to PF01751, Toprim, score 3.2e-11 663951004194 TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947 663951004195 catalytic residues [active] 663951004196 ABC-type metal ion transport system, ATPase component [Inorganic ion transport and metabolism]; Region: AbcC; COG1135 663951004197 ATP-binding cassette domain of methionine transporter; Region: ABC_MetN_methionine_transporter; cd03258 663951004198 Walker A/P-loop; other site 663951004199 ATP binding site [chemical binding]; other site 663951004200 Q-loop/lid; other site 663951004201 ABC transporter signature motif; other site 663951004202 Walker B; other site 663951004203 D-loop; other site 663951004204 H-loop/switch region; other site 663951004205 This domain is found at the C-terminus of ABC transporter proteins involved in D-methionine transport as well as a number of ferredoxin-like proteins; Region: NIL; smart00930 663951004206 HMMPfam hit to PF00005, ABC_tran, score 1.8e-66 663951004207 PS00017 ATP/GTP-binding site motif A (P-loop). 663951004208 PS00211 ABC transporters family signature. 663951004209 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 663951004210 dimer interface [polypeptide binding]; other site 663951004211 conserved gate region; other site 663951004212 ABC-ATPase subunit interface; other site 663951004213 HMMPfam hit to PF00528, BPD_transp_1, score 3e-20 663951004214 5 probable transmembrane helices predicted for SATW20_08870 by TMHMM2.0 at aa 33-55, 68-90, 100-122,160-182 and 202-224 663951004215 PS00402 Binding-protein-dependent transport systems inner membrane comp. sign. 663951004216 ABC-type metal ion transport system, periplasmic component/surface antigen [Inorganic ion transport and metabolism]; Region: NlpA; COG1464 663951004217 NLPA lipoprotein; Region: Lipoprotein_9; pfam03180 663951004218 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 663951004219 HMMPfam hit to PF03180, Lipoprotein_9, score 4.8e-126 663951004220 pathogenicity island, SaPI1 663951004221 Integrase [DNA replication, recombination, and repair]; Region: XerC; COG0582 663951004222 Tn1545-related conjugative transposon integrases, site-specific recombinases, DNA breaking-rejoining enzymes, C-terminal catalytic domain. This CD includes bacterial (gram positive) and phage integrases, including those similar to Tn1545, Tn5252, and...; Region: INT_Tn1545_C; cd01199 663951004223 Int/Topo IB signature motif; other site 663951004224 HMMPfam hit to PF00589, Phage_integrase, score 1.9e-37 663951004225 Staphylococcal/Streptococcal toxin, OB-fold domain; Region: Stap_Strp_toxin; pfam01123 663951004226 Staphylococcal/Streptococcal toxin, beta-grasp domain; Region: Stap_Strp_tox_C; pfam02876 663951004227 HMMPfam hit to PF02876, Stap_Strp_tox_C, score 8.4e-28 663951004228 PS00278 Staphyloccocal enterotoxin/Streptococcal pyrogenic exotoxin signature 2. 663951004229 HMMPfam hit to PF01123, Stap_Strp_toxin, score 3.1e-29 663951004230 Staphylococcal/Streptococcal toxin, OB-fold domain; Region: Stap_Strp_toxin; pfam01123 663951004231 Staphylococcal/Streptococcal toxin, beta-grasp domain; Region: Stap_Strp_tox_C; pfam02876 663951004232 HMMPfam hit to PF02876, Stap_Strp_tox_C, score 2.9e-33 663951004233 PS00278 Staphyloccocal enterotoxin/Streptococcal pyrogenic exotoxin signature 2. 663951004234 PS00277 Staphylococcal enterotoxin/Streptococcal pyrogenic exotoxin signature 1. 663951004235 HMMPfam hit to PF01123, Stap_Strp_toxin, score 2.5e-23 663951004236 1 probable transmembrane helix predicted for SATW20_08910 by TMHMM2.0 at aa 21-43 663951004237 Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396 663951004238 Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093 663951004239 non-specific DNA binding site [nucleotide binding]; other site 663951004240 salt bridge; other site 663951004241 sequence-specific DNA binding site [nucleotide binding]; other site 663951004242 HMMPfam hit to PF01381, HTH_3, score 2.7e-10 663951004243 Predicted helix-turn-helix motif with score 1487.000, SD 4.25 at aa 16-37, sequence LSVKELSTLSGVSQTYISKLEN 663951004244 Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396 663951004245 Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093 663951004246 sequence-specific DNA binding site [nucleotide binding]; other site 663951004247 salt bridge; other site 663951004248 helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cl17320 663951004249 Predicted helix-turn-helix motif with score 1132.000, SD 3.04 at aa 29-50, sequence AKPNALAGIFGISYSSVNRILK 663951004250 1 probable transmembrane helix predicted for SATW20_08950 by TMHMM2.0 at aa 13-35 663951004251 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 663951004252 Protein of unknown function (DUF1474); Region: DUF1474; pfam07342 663951004253 HMMPfam hit to PF07342, DUF1474, score 4.3e-63 663951004254 Primase C terminal 1 (PriCT-1); Region: PriCT_1; smart00942 663951004255 HMMPfam hit to PF08708, PriCT_1, score 2.5e-15 663951004256 Virulence-associated protein E; Region: VirE; pfam05272 663951004257 HMMPfam hit to PF05272, VirE, score 3.3e-133 663951004258 PS00017 ATP/GTP-binding site motif A (P-loop). 663951004259 Spore coat protein [Cell envelope biogenesis, outer membrane]; Region: COG5577 663951004260 Predicted helix-turn-helix motif with score 976.000,SD 2.51 at aa 81-102, sequence RSFKDISNVLECSEQSVRLWYE 663951004261 Phage terminase, small subunit [DNA replication, recombination, and repair]; Region: XtmA; COG3728 663951004262 HMMPfam hit to PF03592, Terminase_2, score 4.8e-78 663951004263 Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3237 663951004264 HMMPfam hit to PF05532, CsbD, score 6.6e-19 663951004265 Predicted membrane protein [Function unknown]; Region: COG2035 663951004266 9 probable transmembrane helices predicted for SATW20_09130 by TMHMM2.0 at aa 20-39, 51-73, 83-105,117-134, 144-166, 173-190, 195-217, 230-252 and 256-278 663951004267 HMMPfam hit to PF04018, DUF368, score 8.2e-128 663951004268 Cysteine desulfurase activator ATPase [Posttranslational modification, protein turnover, chaperones]; Region: sufC; COG0396 663951004269 ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Region: ABC_FeS_Assembly; cd03217 663951004270 Walker A/P-loop; other site 663951004271 ATP binding site [chemical binding]; other site 663951004272 Q-loop/lid; other site 663951004273 ABC transporter signature motif; other site 663951004274 Walker B; other site 663951004275 D-loop; other site 663951004276 H-loop/switch region; other site 663951004277 HMMPfam hit to PF00005, ABC_tran, score 1.5e-29 663951004278 PS00017 ATP/GTP-binding site motif A (P-loop). 663951004279 PS00211 ABC transporters family signature. 663951004280 Cysteine desulfurase activator SufB [Posttranslational modification, protein turnover, chaperones]; Region: SufB; COG0719 663951004281 FeS assembly protein SufD; Region: sufD; TIGR01981 663951004282 HMMPfam hit to PF01458, UPF0051, score 1.3e-68 663951004283 Selenocysteine lyase/Cysteine desulfurase [Posttranslational modification, protein turnover, chaperones]; Region: csdA; COG0520 663951004284 Cysteine desulfurase (SufS)-like. This family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to cysteine desulfurase (SufS) and selenocysteine lyase. SufS...; Region: SufS_like; cd06453 663951004285 pyridoxal 5'-phosphate binding pocket [chemical binding]; other site 663951004286 catalytic residue [active] 663951004287 HMMPfam hit to PF00266, Aminotran_5, score 4.9e-232 663951004288 NifU homolog involved in Fe-S cluster formation [Energy production and conversion]; Region: IscU; COG0822 663951004289 Iron-sulfur cluster scaffold-like proteins; Region: IscU_like; cd06664 663951004290 trimerization site [polypeptide binding]; other site 663951004291 active site 663951004292 HMMPfam hit to PF01592, NifU_N, score 2e-43 663951004293 cysteine desulfurase activator complex subunit SufB; Provisional; Region: PRK11814; cl03223 663951004294 FeS assembly protein SufB; Region: sufB; TIGR01980 663951004295 HMMPfam hit to PF01458, UPF0051, score 7e-133 663951004296 3 probable transmembrane helices predicted for SATW20_09190 by TMHMM2.0 at aa 4-21, 42-71 and 86-103 663951004297 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 663951004298 Putative Mg2+ and Co2+ transporter CorB [Inorganic ion transport and metabolism]; Region: CorB; COG4536 663951004299 Domain of unknown function DUF21; Region: DUF21; pfam01595 663951004300 This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590 663951004301 HMMPfam hit to PF01595, DUF21, score 2.9e-52 663951004302 4 probable transmembrane helices predicted for SATW20_09200 by TMHMM2.0 at aa 2-24, 54-73, 80-102 and 117-139 663951004303 HMMPfam hit to PF00571, CBS, score 1.4e-17 663951004304 Dioxygenases related to 2-nitropropane dioxygenase [General function prediction only]; Region: COG2070 663951004305 2-Nitropropane dioxygenase (NPD), one of the nitroalkane oxidizing enzyme families, catalyzes oxidative denitrification of nitroalkanes to their corresponding carbonyl compounds and nitrites. NDP is a member of the NAD(P)H-dependent flavin oxidoreductase...; Region: NPD_like; cd04730 663951004306 FMN binding site [chemical binding]; other site 663951004307 substrate binding site [chemical binding]; other site 663951004308 putative catalytic residue [active] 663951004309 HMMPfam hit to PF03060, NPD, score 1.5e-100 663951004310 PS00912 Dihydroorotate dehydrogenase signature 2. 663951004311 Uncharacterized conserved protein [Function unknown]; Region: COG1801 663951004312 HMMPfam hit to PF01904, DUF72, score 2.5e-111 663951004313 Sulfite exporter TauE/SafE; Region: TauE; pfam01925 663951004314 HMMPfam hit to PF01925, DUF81, score 6.8e-47 663951004315 8 probable transmembrane helices predicted for SATW20_09230 by TMHMM2.0 at aa 7-29, 49-71, 83-105,110-127, 159-181, 196-218, 223-245 and 255-274 663951004316 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases [Nucleotide transport and metabolism]; Region: UshA; COG0737 663951004317 Escherichia coli UshA-like family, N-terminal metallophosphatase domain; Region: MPP_UshA_N_like; cd00845 663951004318 active site 663951004319 metal binding site [ion binding]; metal-binding site 663951004320 5'-nucleotidase, C-terminal domain; Region: 5_nucleotid_C; pfam02872 663951004321 HMMPfam hit to PF00149, Metallophos, score 4.1e-12 663951004322 lipoyl synthase; Provisional; Region: PRK05481 663951004323 Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335 663951004324 FeS/SAM binding site; other site 663951004325 HMMPfam hit to PF04055, Radical_SAM, score 3.3e-22 663951004326 Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4470 663951004327 HMMPfam hit to PF06265, DUF1027, score 2.6e-58 663951004328 Protein of unknown function (DUF3055); Region: DUF3055; pfam11256 663951004329 Uncharacterized conserved protein [Function unknown]; Region: COG2445 663951004330 HMMPfam hit to PF01934, DUF86, score 6.9e-32 663951004331 Predicted sugar phosphatases of the HAD superfamily [Carbohydrate transport and metabolism]; Region: NagD; COG0647 663951004332 Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427 663951004333 active site 663951004334 motif I; other site 663951004335 motif II; other site 663951004336 Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427 663951004337 HMMPfam hit to PF00702, Hydrolase, score 1e-21 663951004338 Lactate dehydrogenase and related dehydrogenases [Energy production and conversion / Coenzyme metabolism / General function prediction only]; Region: LdhA; COG1052 663951004339 D-glycerate dehydrogenase/hydroxypyruvate reductase (GDH); Region: GDH; cd05301 663951004340 dimerization interface [polypeptide binding]; other site 663951004341 ligand binding site [chemical binding]; other site 663951004342 NADP binding site [chemical binding]; other site 663951004343 catalytic site [active] 663951004344 HMMPfam hit to PF00389, 2-Hacid_dh, score 4.8e-38 663951004345 HMMPfam hit to PF02826, 2-Hacid_dh_C, score 3.9e-90 663951004346 PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 663951004347 D-Ala-teichoic acid biosynthesis protein; Region: DUF3687; pfam12459 663951004348 1 probable transmembrane helix predicted for SATW20_09310 by TMHMM2.0 at aa 15-37 663951004349 D-alanine--poly(phosphoribitol) ligase subunit 1; Provisional; Region: PRK04813 663951004350 D-alanine:D-alanyl carrier protein ligase (DltA); Region: DltA; cd05945 663951004351 acyl-activating enzyme (AAE) consensus motif; other site 663951004352 AMP binding site [chemical binding]; other site 663951004353 HMMPfam hit to PF00501, AMP-binding, score 7.4e-102 663951004354 PS00697 ATP-dependent DNA ligase AMP-binding site. 663951004355 D-alanyl-lipoteichoic acid biosynthesis protein DltB; Region: LTA_dltB; TIGR04091 663951004356 10 probable transmembrane helices predicted for SATW20_09330 by TMHMM2.0 at aa 4-26, 31-48, 58-80, 93-115,130-147, 210-232, 247-269, 323-340, 345-364 and 377-399 663951004357 HMMPfam hit to PF03062, MBOAT, score 9.6e-106 663951004358 D-alanine--poly(phosphoribitol) ligase subunit 2; Validated; Region: PRK05087 663951004359 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein) [Cell envelope biogenesis, outer membrane]; Region: DltD; COG3966 663951004360 DltD N-terminal region; Region: DltD_N; pfam04915 663951004361 DltD central region; Region: DltD_M; pfam04918 663951004362 DltD C-terminal region; Region: DltD_C; pfam04914 663951004363 1 probable transmembrane helix predicted for SATW20_09350 by TMHMM2.0 at aa 5-27 663951004364 HMMPfam hit to PF04915, DltD_N, score 6.5e-34 663951004365 HMMPfam hit to PF04918, DltD_M, score 3e-83 663951004366 HMMPfam hit to PF04914, DltD_C, score 5.8e-77 663951004367 Thioredoxin-like proteins and domains [Posttranslational modification, protein turnover, chaperones]; Region: COG0694 663951004368 HMMPfam hit to PF01106, NifU, score 6.8e-37 663951004369 Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4837 663951004370 HMMPfam hit to PF07315, DUF1462, score 1.9e-72 663951004371 NADH dehydrogenase, FAD-containing subunit [Energy production and conversion]; Region: Ndh; COG1252 663951004372 Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070 663951004373 HMMPfam hit to PF07992, Pyr_redox_2, score 2.4e-10 663951004374 HMMPfam hit to PF00070, Pyr_redox, score 5.6e-15 663951004375 hypothetical protein; Provisional; Region: PRK13669 663951004376 HMMPfam hit to PF07293, DUF1450, score 2.3e-41 663951004377 Fe-S cluster assembly scaffold protein [Posttranslational modification, protein turnover, chaperones]; Region: sufA; COG0316 663951004378 HMMPfam hit to PF01521, Fe-S_biosyn, score 3e-33 663951004379 PS01152 Hypothetical hesB/yadR/yfhF family signature. 663951004380 NADH dehydrogenase, FAD-containing subunit [Energy production and conversion]; Region: Ndh; COG1252 663951004381 Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070 663951004382 HMMPfam hit to PF07992, Pyr_redox_2, score 5.4e-08 663951004383 HMMPfam hit to PF00070, Pyr_redox, score 8.1e-07 663951004384 Leucyl aminopeptidase [Amino acid transport and metabolism]; Region: PepB; COG0260 663951004385 Cytosol aminopeptidase family, N-terminal and catalytic domains. Family M17 contains zinc- and manganese-dependent exopeptidases ( EC 3.4.11.1), including leucine aminopeptidase. They catalyze removal of amino acids from the N-terminus of a protein and...; Region: Peptidase_M17; cd00433 663951004386 interface (dimer of trimers) [polypeptide binding]; other site 663951004387 Substrate-binding/catalytic site; other site 663951004388 Zn-binding sites [ion binding]; other site 663951004389 HMMPfam hit to PF02789, Peptidase_M17_N, score 4.7e-14 663951004390 HMMPfam hit to PF00883, Peptidase_M17, score 4.2e-121 663951004391 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 663951004392 PS00631 Cytosol aminopeptidase signature. 663951004393 Predicted permease [General function prediction only]; Region: COG2056 663951004394 Na+-H+ antiporter family; Region: Na_H_antiport_2; pfam13726 663951004395 H+/citrate symporter [Energy production and conversion]; Region: CitM; cl17620 663951004396 12 probable transmembrane helices predicted for SATW20_09430 by TMHMM2.0 at aa 7-29, 58-77, 98-115,119-141, 148-170, 190-212, 233-255, 259-277, 290-312,332-354, 361-383 and 420-437 663951004397 HMMPfam hit to PF03553, Na_H_antiporter, score 1.4e-88 663951004398 PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria. Although orthologs of PaaI exist in archaea and eukaryotes, their function has not...; Region: PaaI_thioesterase; cd03443 663951004399 CoenzymeA binding site [chemical binding]; other site 663951004400 subunit interaction site [polypeptide binding]; other site 663951004401 PHB binding site; other site 663951004402 HMMPfam hit to PF03061, 4HBT, score 1e-16 663951004403 NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500 663951004404 NADH dehydrogenase, FAD-containing subunit [Energy production and conversion]; Region: Ndh; COG1252 663951004405 putative monovalent cation/H+ antiporter subunit G; Reviewed; Region: PRK12587 663951004406 HMMPfam hit to PF03334, PhaG_MnhG_YufB, score 1.9e-56 663951004407 3 probable transmembrane helices predicted for SATW20_09460 by TMHMM2.0 at aa 7-29, 44-66 and 71-90 663951004408 putative monovalent cation/H+ antiporter subunit F; Reviewed; Region: PRK12600 663951004409 HMMPfam hit to PF04066, MrpF_PhaF, score 3e-21 663951004410 3 probable transmembrane helices predicted for SATW20_09470 by TMHMM2.0 at aa 5-27, 34-56 and 60-82 663951004411 Monovalent Cation (K+ or Na+):Proton Antiporter-3 (CPA3) subfamily; Region: 2a6301s05; TIGR00942 663951004412 HMMPfam hit to PF01899, MNHE, score 9.5e-16 663951004413 4 probable transmembrane helices predicted for SATW20_09480 by TMHMM2.0 at aa 5-22, 27-45, 52-69 and 100-122 663951004414 putative monovalent cation/H+ antiporter subunit D; Reviewed; Region: PRK07691 663951004415 NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361 663951004416 14 probable transmembrane helices predicted for SATW20_09490 by TMHMM2.0 at aa 6-25, 32-54, 74-96, 109-126,131-153, 165-187, 211-233, 238-260, 275-297, 304-323,328-350, 371-393, 408-430 and 451-470 663951004417 HMMPfam hit to PF00361, Oxidored_q1, score 5.4e-48 663951004418 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 663951004419 putative monovalent cation/H+ antiporter subunit C; Reviewed; Region: PRK08600 663951004420 HMMPfam hit to PF00420, Oxidored_q2, score 1.9e-05 663951004421 1 probable transmembrane helix predicted for SATW20_09500 by TMHMM2.0 at aa 41-63 663951004422 putative monovalent cation/H+ antiporter subunit B; Reviewed; Region: PRK12573 663951004423 4 probable transmembrane helices predicted for SATW20_09510 by TMHMM2.0 at aa 9-31, 35-57, 70-92 and 116-138 663951004424 HMMPfam hit to PF04039, MnhB, score 1.7e-44 663951004425 monovalent cation/H+ antiporter subunit A; Reviewed; Region: PRK12645 663951004426 NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361 663951004427 Multisubunit Na+/H+ antiporter, MnhB subunit [Inorganic ion transport and metabolism]; Region: MnhB; COG2111 663951004428 21 probable transmembrane helices predicted for SATW20_09520 by TMHMM2.0 at aa 4-25, 30-49, 79-101,108-127, 131-153, 166-188, 208-230, 243-265, 270-289,302-324, 339-361, 373-395, 429-451, 472-494, 526-548,589-611, 621-641, 646-668, 672-694, 707-729 and 767-784 663951004429 HMMPfam hit to PF00361, Oxidored_q1, score 1.2e-65 663951004430 HMMPfam hit to PF00662, Oxidored_q1_N, score 3.7e-06 663951004431 Kinase associated protein B; Region: KapB; pfam08810 663951004432 HMMPfam hit to PF08810, KapB, score 1.2e-73 663951004433 cyclophilin: cyclophilin-type peptidylprolyl cis- trans isomerases. This family contains eukaryotic, bacterial and archeal proteins which exhibit a peptidylprolyl cis- trans isomerases activity (PPIase, Rotamase) and in addition bind the...; Region: cyclophilin; cl00197 663951004434 active site 663951004435 HMMPfam hit to PF00160, Pro_isomerase, score 2.4e-50 663951004436 general stress protein 13; Validated; Region: PRK08059 663951004437 S1_RPS1_repeat_hs4: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_hs4; cd05692 663951004438 RNA binding site [nucleotide binding]; other site 663951004439 HMMPfam hit to PF00575, S1, score 2.3e-17 663951004440 NADH:flavin oxidoreductases, Old Yellow Enzyme family [Energy production and conversion]; Region: NemA; COG1902 663951004441 Old yellow enzyme (OYE)-related FMN binding domain, group 4. Each monomer of OYE contains FMN as a non-covalently bound cofactor, uses NADPH as a reducing agent with oxygens, quinones, and alpha,beta-unsaturated aldehydes and ketones, and can act as...; Region: OYE_like_4_FMN; cd04735 663951004442 putative active site [active] 663951004443 putative FMN binding site [chemical binding]; other site 663951004444 putative substrate binding site [chemical binding]; other site 663951004445 putative catalytic residue [active] 663951004446 HMMPfam hit to PF00724, Oxidored_FMN, score 2.5e-79 663951004447 ornithine--oxo-acid transaminase; Provisional; Region: rocD; PRK04073 663951004448 Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610 663951004449 inhibitor-cofactor binding pocket; inhibition site 663951004450 pyridoxal 5'-phosphate binding site [chemical binding]; other site 663951004451 catalytic residue [active] 663951004452 HMMPfam hit to PF00202, Aminotran_3, score 2.7e-172 663951004453 PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 663951004454 Glutamate dehydrogenase/leucine dehydrogenase [Amino acid transport and metabolism]; Region: GdhA; COG0334 663951004455 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain; Region: ELFV_dehydrog_N; pfam02812 663951004456 NAD(P) binding domain of glutamate dehydrogenase, subgroup 1; Region: NAD_bind_1_Glu_DH; cd01076 663951004457 NAD(P) binding site [chemical binding]; other site 663951004458 HMMPfam hit to PF02812, ELFV_dehydrog_N, score 4.7e-79 663951004459 PS00074 Glu / Leu / Phe / Val dehydrogenases active site. 663951004460 HMMPfam hit to PF00208, ELFV_dehydrog, score 5.2e-124 663951004461 Glycerophosphoryl diester phosphodiesterase [Energy production and conversion]; Region: UgpQ; COG0584 663951004462 Glycerophosphodiester phosphodiesterase domain of Staphylococcus aureus and similar proteins; Region: GDPD_SaGlpQ_like; cd08601 663951004463 active site 663951004464 catalytic site [active] 663951004465 metal binding site [ion binding]; metal-binding site 663951004466 HMMPfam hit to PF03009, GDPD, score 8.2e-57 663951004467 argininosuccinate lyase; Provisional; Region: PRK00855 663951004468 Argininosuccinate lyase (argininosuccinase, ASAL); Region: Argininosuccinate_lyase; cd01359 663951004469 active sites [active] 663951004470 tetramer interface [polypeptide binding]; other site 663951004471 HMMPfam hit to PF00206, Lyase_1, score 2.6e-83 663951004472 PS00163 Fumarate lyases signature. 663951004473 argininosuccinate synthase; Provisional; Region: PRK13820 663951004474 Argininosuccinate synthase. The Argininosuccinate synthase is a urea cycle enzyme that catalyzes the penultimate step in arginine biosynthesis: the ATP-dependent ligation of citrulline to aspartate to form argininosuccinate, AMP and pyrophosphate . In...; Region: Argininosuccinate_Synthase; cd01999 663951004475 ANP binding site [chemical binding]; other site 663951004476 Substrate Binding Site II [chemical binding]; other site 663951004477 Substrate Binding Site I [chemical binding]; other site 663951004478 HMMPfam hit to PF00764, Arginosuc_synth, score 4.5e-224 663951004479 PS00565 Argininosuccinate synthase signature 2. 663951004480 PS00564 Argininosuccinate synthase signature 1. 663951004481 glucose-6-phosphate isomerase; Provisional; Region: pgi; PRK14097 663951004482 Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the first SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_1; cd05015 663951004483 active site 663951004484 dimer interface [polypeptide binding]; other site 663951004485 Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the second SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_2; cd05016 663951004486 dimer interface [polypeptide binding]; other site 663951004487 active site 663951004488 HMMPfam hit to PF00342, PGI, score 6e-160 663951004489 PS00765 Phosphoglucose isomerase signature 1. 663951004490 Uncharacterized conserved protein [Function unknown]; Region: COG0398 663951004491 5 probable transmembrane helices predicted for SATW20_09630 by TMHMM2.0 at aa 21-43, 48-70, 100-122,132-151 and 156-178 663951004492 HMMPfam hit to PF09335, SNARE_assoc, score 3.1e-23 663951004493 signal peptidase I, bacterial type; Region: sigpep_I_bact; TIGR02227 663951004494 The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530 663951004495 Catalytic site [active] 663951004496 1 probable transmembrane helix predicted for SATW20_09640 by TMHMM2.0 at aa 7-29 663951004497 HMMPfam hit to PF00717, Peptidase_S24, score 8e-10 663951004498 signal peptidase I, bacterial type; Region: sigpep_I_bact; TIGR02227 663951004499 The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530 663951004500 Catalytic site [active] 663951004501 1 probable transmembrane helix predicted for SATW20_09650 by TMHMM2.0 at aa 5-27 663951004502 HMMPfam hit to PF00717, Peptidase_S24, score 1.1e-23 663951004503 PS00501 Signal peptidases I serine active site. 663951004504 PS00760 Signal peptidases I lysine active site. 663951004505 PS00761 Signal peptidases I signature 3. 663951004506 helicase-exonuclease AddAB, AddB subunit; Region: addB_Gpos; TIGR02773 663951004507 PD-(D/E)XK nuclease superfamily; Region: PDDEXK_1; pfam12705 663951004508 PS00017 ATP/GTP-binding site motif A (P-loop). 663951004509 HMMPfam hit to PF00580, UvrD-helicase, score 3.7e-05 663951004510 helicase-exonuclease AddAB, AddA subunit, Firmicutes type; Region: addA_Gpos; TIGR02785 663951004511 Part of AAA domain; Region: AAA_19; pfam13245 663951004512 Family description; Region: UvrD_C_2; pfam13538 663951004513 PD-(D/E)XK nuclease superfamily; Region: PDDEXK_1; pfam12705 663951004514 HMMPfam hit to PF00580, UvrD-helicase, score 3.2e-82 663951004515 PS00017 ATP/GTP-binding site motif A (P-loop). 663951004516 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) [Secondary metabolites biosynthesis, transport, and catabolism]; Region: MhpD; COG0179 663951004517 Fumarylacetoacetate (FAA) hydrolase family; Region: FAA_hydrolase; pfam01557 663951004518 HMMPfam hit to PF01557, FAA_hydrolase, score 6.7e-57 663951004519 hypothetical protein; Provisional; Region: PRK13673 663951004520 HMMPfam hit to PF07457, DUF1516, score 1.1e-75 663951004521 4 probable transmembrane helices predicted for SATW20_09690 by TMHMM2.0 at aa 5-24, 37-56, 66-88 and 100-122 663951004522 coenzyme A disulfide reductase; Provisional; Region: PRK13512 663951004523 NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500 663951004524 Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070 663951004525 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852 663951004526 HMMPfam hit to PF02852, Pyr_redox_dim, score 1.6e-05 663951004527 HMMPfam hit to PF07992, Pyr_redox_2, score 6.2e-49 663951004528 HMMPfam hit to PF00070, Pyr_redox, score 8.5e-23 663951004529 Predicted hydrolases of the HAD superfamily [General function prediction only]; Region: Cof; COG0561 663951004530 Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427 663951004531 active site 663951004532 motif I; other site 663951004533 motif II; other site 663951004534 Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427 663951004535 HMMPfam hit to PF08282, Hydrolase_3, score 6.1e-84 663951004536 PS01228 Hypothetical cof family signature 1. 663951004537 Predicted metal-sulfur cluster biosynthetic enzyme [General function prediction only]; Region: PaaD; COG2151 663951004538 HMMPfam hit to PF01883, DUF59, score 6.1e-31 663951004539 Predicted acyltransferases [Lipid metabolism]; Region: COG1835 663951004540 yrhL-like subfamily of SGNH-hydrolases, a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely...; Region: SGNH_hydrolase_yrhL_like; cd01840 663951004541 catalytic triad [active] 663951004542 catalytic triad [active] 663951004543 oxyanion hole [active] 663951004544 10 probable transmembrane helices predicted for SATW20_09730 by TMHMM2.0 at aa 13-35, 41-63, 84-103,148-170, 177-199, 237-259, 272-294, 309-328, 335-357 and 377-399 663951004545 HMMPfam hit to PF01757, Acyl_transf_3, score 2.9e-52 663951004546 ATP-dependent chaperone ClpB; Region: chaperone_ClpB; TIGR03346 663951004547 Clp amino terminal domain; Region: Clp_N; pfam02861 663951004548 The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009 663951004549 Walker A motif; other site 663951004550 ATP binding site [chemical binding]; other site 663951004551 Walker B motif; other site 663951004552 arginine finger; other site 663951004553 ATP synthase B/B' CF(0); Region: ATP-synt_B; cl17192 663951004554 The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009 663951004555 Walker A motif; other site 663951004556 ATP binding site [chemical binding]; other site 663951004557 Walker B motif; other site 663951004558 C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431 663951004559 HMMPfam hit to PF02861, Clp_N, score 1e-09 663951004560 HMMPfam hit to PF02861, Clp_N, score 0.00036 663951004561 HMMPfam hit to PF00004, AAA, score 6e-16 663951004562 PS00017 ATP/GTP-binding site motif A (P-loop). 663951004563 PS00870 Chaperonins clpA/B signature 1. 663951004564 HMMPfam hit to PF07724, AAA_2, score 6.6e-108 663951004565 PS00017 ATP/GTP-binding site motif A (P-loop). 663951004566 PS00871 Chaperonins clpA/B signature 2. 663951004567 Transcriptional regulator [Transcription]; Region: LysR; COG0583 663951004568 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 663951004569 The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466 663951004570 dimerization interface [polypeptide binding]; other site 663951004571 HMMPfam hit to PF03466, LysR_substrate, score 1.1e-09 663951004572 HMMPfam hit to PF00126, HTH_1, score 4.6e-14 663951004573 PS00044 Bacterial regulatory proteins, lysR family signature. 663951004574 Predicted helix-turn-helix motif with score 995.000,SD 2.58 at aa 16-37, sequence LNYRLASEEINLTIPSIHKQIK 663951004575 Isopropylmalate/homocitrate/citramalate synthases [Amino acid transport and metabolism]; Region: LeuA; COG0119 663951004576 DRE-TIM metallolyase superfamily; Region: DRE_TIM_metallolyase; cl07974 663951004577 active site 663951004578 catalytic residues [active] 663951004579 metal binding site [ion binding]; metal-binding site 663951004580 HMMPfam hit to PF00682, HMGL-like, score 4.1e-43 663951004581 PS00816 Alpha-isopropylmalate and homocitrate synthases signature 2. 663951004582 Putative translation factor (SUA5) [Translation, ribosomal structure and biogenesis]; Region: SUA5; COG0009 663951004583 HMMPfam hit to PF01300, Sua5_yciO_yrdC, score 1.6e-09 663951004584 HMMPfam hit to PF07690, MFS_1, score 2.4e-05 663951004585 11 probable transmembrane helices predicted for SATW20_09780 by TMHMM2.0 at aa 13-30, 35-54, 71-88, 92-111,131-153, 157-176, 200-222, 232-254, 267-289, 314-336 and 343-362 663951004586 PhosphatidylEthanolamine-Binding Protein (PEBP) domain present in bacteria and archaea; Region: PEBP_bact_arch; cd00865 663951004587 substrate binding site [chemical binding]; other site 663951004588 MAP domain; Region: MAP; pfam03642 663951004589 HMMPfam hit to PF03642, MAP, score 7.3e-54 663951004590 Protein of unknown function (DUF2929); Region: DUF2929; pfam11151 663951004591 2 probable transmembrane helices predicted for SATW20_09810 by TMHMM2.0 at aa 4-26 and 31-53 663951004592 3-oxoacyl-(acyl carrier protein) synthase III; Reviewed; Region: PRK09352 663951004593 Ketoacyl-acyl carrier protein synthase III (KASIII) initiates the elongation in type II fatty acid synthase systems. It is found in bacteria and plants. Elongation of fatty acids in the type II systems occurs by Claisen condensation of malonyl-acyl...; Region: KAS_III; cd00830 663951004594 dimer interface [polypeptide binding]; other site 663951004595 active site 663951004596 CoA binding pocket [chemical binding]; other site 663951004597 HMMPfam hit to PF08545, ACP_syn_III, score 2.3e-40 663951004598 HMMPfam hit to PF08541, ACP_syn_III_C, score 3.8e-49 663951004599 beta-ketoacyl-acyl-carrier-protein synthase II; Region: fabF; TIGR03150 663951004600 Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen...; Region: KAS_I_II; cd00834 663951004601 dimer interface [polypeptide binding]; other site 663951004602 active site 663951004603 HMMPfam hit to PF00109, ketoacyl-synt, score 7.3e-85 663951004604 HMMPfam hit to PF02801, Ketoacyl-synt_C, score 5.9e-51 663951004605 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601 663951004606 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 663951004607 dimer interface [polypeptide binding]; other site 663951004608 conserved gate region; other site 663951004609 putative PBP binding loops; other site 663951004610 ABC-ATPase subunit interface; other site 663951004611 6 probable transmembrane helices predicted for SATW20_09840 by TMHMM2.0 at aa 5-27, 97-119, 132-154,164-186, 225-247 and 275-297 663951004612 HMMPfam hit to PF00528, BPD_transp_1, score 1e-51 663951004613 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppC; COG1173 663951004614 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 663951004615 dimer interface [polypeptide binding]; other site 663951004616 conserved gate region; other site 663951004617 putative PBP binding loops; other site 663951004618 ABC-ATPase subunit interface; other site 663951004619 6 probable transmembrane helices predicted for SATW20_09850 by TMHMM2.0 at aa 64-86, 156-178, 191-213,217-236, 267-289 and 320-342 663951004620 HMMPfam hit to PF00528, BPD_transp_1, score 7.3e-41 663951004621 ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppD; COG0444 663951004622 ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257 663951004623 Walker A/P-loop; other site 663951004624 ATP binding site [chemical binding]; other site 663951004625 Q-loop/lid; other site 663951004626 ABC transporter signature motif; other site 663951004627 Walker B; other site 663951004628 D-loop; other site 663951004629 H-loop/switch region; other site 663951004630 Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097 663951004631 HMMPfam hit to PF00005, ABC_tran, score 5.2e-68 663951004632 PS00017 ATP/GTP-binding site motif A (P-loop). 663951004633 PS00211 ABC transporters family signature. 663951004634 HMMPfam hit to PF08352, oligo_HPY, score 5.2e-27 663951004635 ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppF; COG1124 663951004636 ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257 663951004637 Walker A/P-loop; other site 663951004638 ATP binding site [chemical binding]; other site 663951004639 Q-loop/lid; other site 663951004640 ABC transporter signature motif; other site 663951004641 Walker B; other site 663951004642 D-loop; other site 663951004643 H-loop/switch region; other site 663951004644 Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097 663951004645 O-Glycosyl hydrolase family 30; Region: Glyco_hydro_30; pfam02055 663951004646 HMMPfam hit to PF00005, ABC_tran, score 2.9e-62 663951004647 PS00017 ATP/GTP-binding site motif A (P-loop). 663951004648 PS00211 ABC transporters family signature. 663951004649 HMMPfam hit to PF08352, oligo_HPY, score 2.8e-08 663951004650 ABC-type oligopeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: OppA; COG4166 663951004651 The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold; Region: PBP2_OppA; cd08504 663951004652 peptide binding site [polypeptide binding]; other site 663951004653 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 663951004654 HMMPfam hit to PF00496, SBP_bac_5, score 5.8e-81 663951004655 ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747 663951004656 The substrate-binding domain of an ABC-type nickel/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like; cl01709 663951004657 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 663951004658 HMMPfam hit to PF00496, SBP_bac_5, score 1.5e-70 663951004659 ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppD; COG0444 663951004660 ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257 663951004661 Walker A/P-loop; other site 663951004662 ATP binding site [chemical binding]; other site 663951004663 Q-loop/lid; other site 663951004664 ABC transporter signature motif; other site 663951004665 Walker B; other site 663951004666 D-loop; other site 663951004667 H-loop/switch region; other site 663951004668 Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097 663951004669 HMMPfam hit to PF00005, ABC_tran, score 1.4e-59 663951004670 PS00017 ATP/GTP-binding site motif A (P-loop). 663951004671 PS00211 ABC transporters family signature. 663951004672 HMMPfam hit to PF08352, oligo_HPY, score 5e-22 663951004673 dipeptide transporter ATP-binding subunit; Provisional; Region: dppF; PRK11308 663951004674 ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257 663951004675 Walker A/P-loop; other site 663951004676 ATP binding site [chemical binding]; other site 663951004677 Q-loop/lid; other site 663951004678 ABC transporter signature motif; other site 663951004679 Walker B; other site 663951004680 D-loop; other site 663951004681 H-loop/switch region; other site 663951004682 oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; Region: oligo_HPY; TIGR01727 663951004683 HMMPfam hit to PF00005, ABC_tran, score 1.6e-55 663951004684 PS00017 ATP/GTP-binding site motif A (P-loop). 663951004685 PS00211 ABC transporters family signature. 663951004686 HMMPfam hit to PF08352, oligo_HPY, score 1.1e-33 663951004687 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601 663951004688 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 663951004689 dimer interface [polypeptide binding]; other site 663951004690 conserved gate region; other site 663951004691 putative PBP binding loops; other site 663951004692 ABC-ATPase subunit interface; other site 663951004693 6 probable transmembrane helices predicted for SATW20_09920 by TMHMM2.0 at aa 9-31, 99-121, 134-156,184-206, 241-263 and 291-313 663951004694 HMMPfam hit to PF00528, BPD_transp_1, score 3.7e-54 663951004695 oligopeptide ABC transporter permease OppC; Provisional; Region: PRK15406 663951004696 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 663951004697 dimer interface [polypeptide binding]; other site 663951004698 conserved gate region; other site 663951004699 putative PBP binding loops; other site 663951004700 ABC-ATPase subunit interface; other site 663951004701 6 probable transmembrane helices predicted for SATW20_09930 by TMHMM2.0 at aa 21-43, 88-110, 117-139,149-171, 202-224 and 261-283 663951004702 HMMPfam hit to PF00528, BPD_transp_1, score 7.1e-43 663951004703 tryptophanyl-tRNA synthetase II; Reviewed; Region: PRK12282 663951004704 catalytic core domain of tryptophanyl-tRNA synthetase; Region: TrpRS_core; cd00806 663951004705 active site 663951004706 HIGH motif; other site 663951004707 dimer interface [polypeptide binding]; other site 663951004708 KMSKS motif; other site 663951004709 HMMPfam hit to PF00579, tRNA-synt_1b, score 1.3e-106 663951004710 PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 663951004711 Arsenate Reductase (ArsC) family, Spx subfamily; Spx is a unique RNA polymerase (RNAP)-binding protein present in bacilli and some mollicutes. It inhibits transcription by binding to the C-terminal domain of the alpha subunit of RNAP, disrupting complex...; Region: ArsC_Spx; cd03032 663951004712 ArsC family; Region: ArsC; pfam03960 663951004713 putative catalytic residues [active] 663951004714 thiol/disulfide switch; other site 663951004715 HMMPfam hit to PF03960, ArsC, score 3.8e-57 663951004716 adaptor protein; Provisional; Region: PRK02315 663951004717 HMMPfam hit to PF05389, MecA, score 1.4e-127 663951004718 CDS contains a frameshift after codon 85. Similar to Staphylococcus aureus (strain MRSA252) putative uncharacterized protein UniProt:Q6GI86 (EMBL:BX571856) (328 aa) fasta scores: E()=2.2e-127, 97.3% id in 328 aa 663951004719 HMMPfam hit to PF06054, CoiA, score 3.6e-132 663951004720 PS00225 Crystallins beta and gamma 'Greek key' motif signature. 663951004721 Oligoendopeptidase F [Amino acid transport and metabolism]; Region: COG1164 663951004722 Peptidase family M3B Oligopeptidase F (PepF); Region: M3B_PepF_3; cd09608 663951004723 active site 663951004724 Zn binding site [ion binding]; other site 663951004725 HMMPfam hit to PF08439, Peptidase_M3_N, score 8e-25 663951004726 HMMPfam hit to PF01432, Peptidase_M3, score 3.2e-130 663951004727 Predicted dithiol-disulfide isomerase involved in polyketide biosynthesis [Secondary metabolites biosynthesis, transport, and catabolism]; Region: FrnE; COG2761 663951004728 Thioredoxin; Region: Thioredoxin_5; pfam13743 663951004729 Truncated hemoglobins (trHbs) are a family of oxygen-binding heme proteins found in cyanobacteria, eubacteria, unicellular eukaryotes, and plants. The truncated hemoglobins have a characteristic two-over-two alpha helical folding pattern that is distinct...; Region: Trunc_globin; cd00454 663951004730 apolar tunnel; other site 663951004731 heme binding site [chemical binding]; other site 663951004732 dimerization interface [polypeptide binding]; other site 663951004733 HMMPfam hit to PF01152, Bac_globin, score 1.3e-23 663951004734 Uncharacterized subgroup 1 of the CYTH-like superfamily; Region: CYTH-like_Pase_1; cd07762 663951004735 putative active site [active] 663951004736 putative metal binding residues [ion binding]; other site 663951004737 signature motif; other site 663951004738 putative triphosphate binding site [ion binding]; other site 663951004739 HMMPfam hit to PF01928, CYTH, score 5.5e-49 663951004740 Nucleotidyltransferase (NT) domain of RelA- and SpoT-like ppGpp synthetases and hydrolases; Region: NT_Rel-Spo_like; cd05399 663951004741 synthetase active site [active] 663951004742 NTP binding site [chemical binding]; other site 663951004743 metal binding site [ion binding]; metal-binding site 663951004744 HMMPfam hit to PF04607, RelA_SpoT, score 4.4e-44 663951004745 inorganic polyphosphate/ATP-NAD kinase; Provisional; Region: ppnK; PRK04885 663951004746 ATP-NAD kinase; Region: NAD_kinase; pfam01513 663951004747 HMMPfam hit to PF01513, NAD_kinase, score 1.2e-55 663951004748 Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564 663951004749 Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869 663951004750 active site 663951004751 HMMPfam hit to PF00849, PseudoU_synth_2, score 1.7e-36 663951004752 PS01129 Rlu family of pseudouridine synthase signature. 663951004753 Mg/Co/Ni transporter MgtE (contains CBS domain) [Inorganic ion transport and metabolism]; Region: MgtE; COG2239 663951004754 MgtE intracellular N domain; Region: MgtE_N; smart00924 663951004755 This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domain in the magnesium transporter, MgtE. MgtE and its homologs are found in eubacteria, archaebacteria, and eukaryota. Members of this family transport Mg2+ or other...; Region: CBS_pair_Mg_transporter; cd04606 663951004756 Divalent cation transporter; Region: MgtE; pfam01769 663951004757 HMMPfam hit to PF03448, MgtE_N, score 5.5e-39 663951004758 HMMPfam hit to PF00571, CBS, score 1e-21 663951004759 5 probable transmembrane helices predicted for SATW20_10060 by TMHMM2.0 at aa 295-312, 322-341, 369-391,396-418 and 431-453 663951004760 HMMPfam hit to PF01769, MgtE, score 6.2e-34 663951004761 Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: KefB; COG0475 663951004762 Sodium/hydrogen exchanger family; Region: Na_H_Exchanger; pfam00999 663951004763 K+ transport systems, NAD-binding component [Inorganic ion transport and metabolism]; Region: TrkA; COG0569 663951004764 TrkA-N domain; Region: TrkA_N; pfam02254 663951004765 TrkA-C domain; Region: TrkA_C; pfam02080 663951004766 12 probable transmembrane helices predicted for SATW20_10070 by TMHMM2.0 at aa 4-20, 27-49, 54-76, 98-120,130-149, 162-184, 190-212, 233-262, 277-299, 306-328,338-355 and 368-387 663951004767 HMMPfam hit to PF00999, Na_H_Exchanger, score 2.2e-97 663951004768 HMMPfam hit to PF02254, TrkA_N, score 1.9e-10 663951004769 HMMPfam hit to PF02080, TrkA_C, score 1.3e-11 663951004770 enoyl-(acyl carrier protein) reductase; Provisional; Region: PRK08594 663951004771 Enoyl acyl carrier protein (ACP) reductase (ENR), divergent SDR; Region: ENR_SDR; cd05372 663951004772 NAD binding site [chemical binding]; other site 663951004773 homotetramer interface [polypeptide binding]; other site 663951004774 homodimer interface [polypeptide binding]; other site 663951004775 substrate binding site [chemical binding]; other site 663951004776 active site 663951004777 Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; COG0628 663951004778 Domain of unknown function DUF20; Region: UPF0118; pfam01594 663951004779 9 probable transmembrane helices predicted for SATW20_10090 by TMHMM2.0 at aa 5-23, 30-52, 72-94, 155-177,213-235, 242-261, 265-287, 299-318 and 323-345 663951004780 HMMPfam hit to PF01594, UPF0118, score 9.8e-61 663951004781 Na+/alanine symporter [Amino acid transport and metabolism]; Region: AlsT; COG1115 663951004782 Sodium:alanine symporter family; Region: Na_Ala_symp; cl00548 663951004783 10 probable transmembrane helices predicted for SATW20_10100 by TMHMM2.0 at aa 12-31, 86-108, 140-162,177-199, 206-228, 243-262, 296-318, 380-402, 419-437 and 447-469 663951004784 HMMPfam hit to PF01235, Na_Ala_symp, score 4.8e-159 663951004785 PS00873 Sodium:alanine symporter family signature. 663951004786 Predicted hydrolase of the alpha/beta superfamily [General function prediction only]; Region: COG2819 663951004787 Putative esterase; Region: Esterase; pfam00756 663951004788 HMMPfam hit to PF00756, Esterase, score 4.6e-86 663951004789 hypothetical protein; Provisional; Region: PRK13679 663951004790 LigT like Phosphoesterase; Region: LigT_PEase; pfam02834 663951004791 HMMPfam hit to PF02834, 2_5_RNA_ligase, score 2e-11 663951004792 Major Facilitator Superfamily; Region: MFS_1; pfam07690 663951004793 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 663951004794 putative substrate translocation pore; other site 663951004795 12 probable transmembrane helices predicted for SATW20_10130 by TMHMM2.0 at aa 13-35, 39-61, 80-99,104-126, 139-161, 166-184, 211-233, 246-268, 275-297,302-324, 337-359 and 369-391 663951004796 HMMPfam hit to PF07690, MFS_1, score 1.5e-37 663951004797 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 663951004798 diacylglycerol glucosyltransferase; Provisional; Region: PRK13608 663951004799 Monogalactosyldiacylglycerol (MGDG) synthase; Region: MGDG_synth; pfam06925 663951004800 Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013 663951004801 HMMPfam hit to PF00534, Glycos_transf_1, score 0.0017 663951004802 HMMPfam hit to PF06925, MGDG_synth, score 1e-74 663951004803 UDP-N-acetylmuramoylalanyl-D-glutamate--L-lysine ligase; Provisional; Region: PRK14022 663951004804 Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225 663951004805 Mur ligase middle domain; Region: Mur_ligase_M; pfam08245 663951004806 Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875 663951004807 HMMPfam hit to PF01225, Mur_ligase, score 2.2e-13 663951004808 HMMPfam hit to PF08245, Mur_ligase_M, score 4e-74 663951004809 HMMPfam hit to PF02875, Mur_ligase_C, score 1.7e-27 663951004810 YueH-like protein; Region: YueH; pfam14166 663951004811 peptide chain release factor 3; Provisional; Region: prfC; PRK00741 663951004812 Release Factor 3 (RF3) protein involved in the terminal step of translocation in bacteria; Region: RF3; cd04169 663951004813 G1 box; other site 663951004814 putative GEF interaction site [polypeptide binding]; other site 663951004815 GTP/Mg2+ binding site [chemical binding]; other site 663951004816 Switch I region; other site 663951004817 G2 box; other site 663951004818 G3 box; other site 663951004819 Switch II region; other site 663951004820 G4 box; other site 663951004821 G5 box; other site 663951004822 RF3_II: this subfamily represents the domain II of bacterial Release Factor 3 (RF3). Termination of protein synthesis by the ribosome requires two release factor (RF) classes. The class II RF3 is a GTPase that removes class I RFs (RF1 or RF2) from the...; Region: RF3_II; cd03689 663951004823 HMMPfam hit to PF00009, GTP_EFTU, score 1.7e-80 663951004824 PS00301 GTP-binding elongation factors signature. 663951004825 HMMPfam hit to PF03144, GTP_EFTU_D2, score 1.6e-12 663951004826 integral membrane protein, YkoY family; Region: R_switched_YkoY; TIGR03716 663951004827 7 probable transmembrane helices predicted for SATW20_10180 by TMHMM2.0 at aa 5-27, 48-70, 74-93, 133-155,170-192, 205-227 and 237-259 663951004828 HMMPfam hit to PF03741, TerC, score 5.5e-24 663951004829 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain [Posttranslational modification, protein turnover, chaperones]; Region: DegQ; COG0265 663951004830 Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365 663951004831 PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987 663951004832 1 probable transmembrane helix predicted for SATW20_10190 by TMHMM2.0 at aa 410-432 663951004833 HMMPfam hit to PF00089, Trypsin, score 9.6e-11 663951004834 potassium uptake protein, TrkH family; Region: 2a38; TIGR00933 663951004835 Trk-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: TrkG; COG0168 663951004836 10 probable transmembrane helices predicted for SATW20_10200 by TMHMM2.0 at aa 15-37, 50-68, 78-100,128-150, 193-215, 228-250, 312-334, 355-377, 382-404 and 413-435 663951004837 HMMPfam hit to PF02386, TrkH, score 1.8e-82 663951004838 PS00017 ATP/GTP-binding site motif A (P-loop). 663951004839 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases [Nucleotide transport and metabolism]; Region: UshA; COG0737 663951004840 metallophosphatase superfamily, metallophosphatase domain; Region: MPP_superfamily; cl13995 663951004841 active site 663951004842 metal binding site [ion binding]; metal-binding site 663951004843 5'-nucleotidase, C-terminal domain; Region: 5_nucleotid_C; pfam02872 663951004844 1 probable transmembrane helix predicted for SATW20_10210 by TMHMM2.0 at aa 47-69 663951004845 HMMPfam hit to PF02872, 5_nucleotid_C, score 3.3e-26 663951004846 Genetic competence transcription factor [Transcription]; Region: ComK; COG4903 663951004847 HMMPfam hit to PF06338, ComK, score 9.3e-128 663951004848 PS00453 FKBP-type peptidyl-prolyl cis-trans isomerase signature 1. 663951004849 IDEAL domain; Region: IDEAL; pfam08858 663951004850 HMMPfam hit to PF08858, IDEAL, score 7.3e-13 663951004851 Lipoate-protein ligase A [Coenzyme metabolism]; Region: LplA; COG0095 663951004852 lipoyltransferase and lipoate-protein ligase; Region: lipoyltrans; TIGR00545 663951004853 Bacterial lipoate protein ligase C-terminus; Region: Lip_prot_lig_C; pfam10437 663951004854 HMMPfam hit to PF03099, BPL_LipA_LipB, score 5e-23 663951004855 Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4873 663951004856 CAAX protease self-immunity; Region: Abi; pfam02517 663951004857 6 probable transmembrane helices predicted for SATW20_10260 by TMHMM2.0 at aa 10-27, 39-61, 81-98,111-130, 134-151 and 158-175 663951004858 HMMPfam hit to PF02517, Abi, score 0.0071 663951004859 CDS lacks appropriate translational start site. Possible alternative translational start sites which are affected by mutations 663951004860 Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4652 663951004861 Protein of unknown function (DUF1430); Region: DUF1430; pfam07242 663951004862 7 probable transmembrane helices predicted for SATW20_10280 by TMHMM2.0 at aa 6-25, 162-181, 212-234,241-263, 551-573, 594-616 and 620-642 663951004863 PS00904 Protein prenyltransferases alpha subunit repeat signature. 663951004864 HMMPfam hit to PF07242, DUF1430, score 2.8e-28 663951004865 Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG5294 663951004866 1 probable transmembrane helix predicted for SATW20_10290 by TMHMM2.0 at aa 5-27 663951004867 ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255 663951004868 putative bacteriocin export ABC transporter, lactococcin 972 group; Region: L_ocin_972_ABC; TIGR03608 663951004869 Walker A/P-loop; other site 663951004870 ATP binding site [chemical binding]; other site 663951004871 Q-loop/lid; other site 663951004872 ABC transporter signature motif; other site 663951004873 Walker B; other site 663951004874 D-loop; other site 663951004875 H-loop/switch region; other site 663951004876 HMMPfam hit to PF00005, ABC_tran, score 6.2e-44 663951004877 PS00017 ATP/GTP-binding site motif A (P-loop). 663951004878 PS00211 ABC transporters family signature. 663951004879 Domain of unknown function (DUF1975); Region: DUF1975; pfam09318 663951004880 This family is most closely related to the GT1 family of glycosyltransferases and is named after gtfA in Streptococcus gordonii, where it plays a role in the O-linked glycosylation of GspB, a cell surface glycoprotein involved in platelet binding. In...; Region: GT1_gtfA_like; cd04949 663951004881 Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438 663951004882 HMMPfam hit to PF09318, DUF1975, score 2.1e-98 663951004883 HMMPfam hit to PF00534, Glycos_transf_1, score 6.7e-40 663951004884 Predicted membrane protein [Function unknown]; Region: COG2259 663951004885 4 probable transmembrane helices predicted for SATW20_10330 by TMHMM2.0 at aa 7-26, 41-63, 68-90 and 95-112 663951004886 HMMPfam hit to PF07681, DoxX, score 6e-22 663951004887 ABC-type Fe3+-citrate transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: FecB; COG4594 663951004888 Fe3+-siderophore binding domain FhuD. These proteins have been shown to function as initial receptors in ABC transport of Fe3+-siderophores in many eubacterial species. They belong to the TroA-like superfamily of helical backbone metal receptor proteins...; Region: FhuD; cd01146 663951004889 siderophore binding site; other site 663951004890 1 probable transmembrane helix predicted for SATW20_10340 by TMHMM2.0 at aa 5-24 663951004891 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 663951004892 HMMPfam hit to PF01497, Peripla_BP_2, score 1.6e-50 663951004893 Predicted membrane protein [Function unknown]; Region: XynA; COG2314 663951004894 2 probable transmembrane helices predicted for SATW20_10360 by TMHMM2.0 at aa 7-25 and 35-57 663951004895 HMMPfam hit to PF05154, TM2, score 2.1e-18 663951004896 N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301 663951004897 Acetyltransferases [General function prediction only]; Region: RimI; COG0456 663951004898 N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182 663951004899 Coenzyme A binding pocket [chemical binding]; other site 663951004900 HMMPfam hit to PF00583, Acetyltransf_1, score 2.1e-13 663951004901 1,4-dihydroxy-2-naphthoate octaprenyltransferase; Validated; Region: PRK06080 663951004902 UbiA prenyltransferase family; Region: UbiA; pfam01040 663951004903 HMMPfam hit to PF01040, UbiA, score 1.7e-27 663951004904 9 probable transmembrane helices predicted for SATW20_10380 by TMHMM2.0 at aa 21-43, 48-70, 101-123,127-149, 154-176, 181-203, 224-246, 250-272 and 293-310 663951004905 PS00017 ATP/GTP-binding site motif A (P-loop). 663951004906 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 663951004907 Isochorismate synthase [Coenzyme metabolism / Secondary metabolites biosynthesis, transport, and catabolism]; Region: MenF; COG1169 663951004908 isochorismate synthases; Region: isochor_syn; TIGR00543 663951004909 HMMPfam hit to PF00425, Chorismate_bind, score 9.6e-44 663951004910 PS00017 ATP/GTP-binding site motif A (P-loop). 663951004911 2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylate synthase [Coenzyme metabolism]; Region: MenD; COG1165 663951004912 Pyrimidine (PYR) binding domain of 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexadiene-1- carboxylate synthase (MenD) and related proteins; Region: TPP_PYR_MenD; cd07037 663951004913 dimer interface [polypeptide binding]; other site 663951004914 tetramer interface [polypeptide binding]; other site 663951004915 PYR/PP interface [polypeptide binding]; other site 663951004916 TPP binding site [chemical binding]; other site 663951004917 Thiamine pyrophosphate (TPP) family, SHCHC synthase subfamily, TPP-binding module; composed of proteins similar to Escherichia coli 2-succinyl-6-hydroxyl-2,4-cyclohexadiene-1-carboxylic acid (SHCHC) synthase (also called MenD). SHCHC synthase plays a key...; Region: TPP_SHCHC_synthase; cd02009 663951004918 TPP-binding site; other site 663951004919 HMMPfam hit to PF02776, TPP_enzyme_N, score 0.00056 663951004920 2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylate synthase; Region: menH_SHCHC; TIGR03695 663951004921 PGAP1-like protein; Region: PGAP1; pfam07819 663951004922 HMMPfam hit to PF00561, Abhydrolase_1, score 3e-26 663951004923 Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558 663951004924 Enoyl-CoA hydratase/isomerase family; Region: ECH; pfam00378 663951004925 substrate binding site [chemical binding]; other site 663951004926 oxyanion hole (OAH) forming residues; other site 663951004927 trimer interface [polypeptide binding]; other site 663951004928 HMMPfam hit to PF00378, ECH, score 8.1e-79 663951004929 Staphostatin B; Region: Staphostatin_B; pfam09023 663951004930 HMMPfam hit to PF09023, Staphostatin_B, score 8.6e-93 663951004931 Staphopain peptidase C47; Region: Peptidase_C47; pfam05543 663951004932 HMMPfam hit to PF05543, Peptidase_C47, score 8.1e-142 663951004933 PS00639 Eukaryotic thiol (cysteine) proteases histidine active site. 663951004934 1 probable transmembrane helix predicted for SATW20_10440 by TMHMM2.0 at aa 7-29 663951004935 V8-like Glu-specific endopeptidase [Amino acid transport and metabolism]; Region: COG3591 663951004936 HMMPfam hit to PF00089, Trypsin, score 9e-29 663951004937 PS00673 Serine proteases, V8 family, serine active site. 663951004938 PS00672 Serine proteases, V8 family, histidine active site. 663951004939 aminotransferase A; Validated; Region: PRK07683 663951004940 Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609 663951004941 pyridoxal 5'-phosphate binding site [chemical binding]; other site 663951004942 homodimer interface [polypeptide binding]; other site 663951004943 catalytic residue [active] 663951004944 HMMPfam hit to PF00155, Aminotran_1_2, score 2.6e-68 663951004945 PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 663951004946 Fucose 4-O-acetylase and related acetyltransferases [Carbohydrate transport and metabolism]; Region: NolL; COG3594 663951004947 Acyltransferase family; Region: Acyl_transf_3; pfam01757 663951004948 HMMPfam hit to PF01757, Acyl_transf_3, score 8.2e-62 663951004949 10 probable transmembrane helices predicted for SATW20_10470 by TMHMM2.0 at aa 9-28, 38-60, 73-95, 110-129,136-153, 157-175, 188-210, 236-255, 262-281 and 296-318 663951004950 helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347 663951004951 MarR family; Region: MarR; pfam01047 663951004952 HMMPfam hit to PF01047, MarR, score 5.6e-18 663951004953 Predicted helix-turn-helix motif with score 1295.000, SD 3.60 at aa 46-67, sequence LSQYDLTMKISREQSIVSRWIK 663951004954 N-acetylmuramoyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: COG5632 663951004955 Peptidoglycan recognition proteins (PGRPs) are pattern recognition receptors that bind, and in certain cases, hydrolyze peptidoglycans (PGNs) of bacterial cell walls. PGRPs have been divided into three classes: short PGRPs (PGRP-S), that are small (20...; Region: PGRP; cd06583 663951004956 amidase catalytic site [active] 663951004957 Zn binding residues [ion binding]; other site 663951004958 substrate binding site [chemical binding]; other site 663951004959 Beta- N-acetylglucosaminidase [Carbohydrate transport and metabolism]; Region: LytD; COG4193 663951004960 Lysozyme subfamily 2; Region: LYZ2; smart00047 663951004961 HMMPfam hit to PF01832, Glucosaminidase, score 2.4e-69 663951004962 HMMPfam hit to PF01510, Amidase_2, score 1.5e-41 663951004963 N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301 663951004964 Coenzyme A binding pocket [chemical binding]; other site 663951004965 HMMPfam hit to PF00583, Acetyltransf_1, score 8.6e-22 663951004966 Protein of unknown function (DUF2538); Region: DUF2538; pfam10804 663951004967 Transcriptional regulator [Transcription]; Region: LytR; COG1316 663951004968 HMMPfam hit to PF03816, LytR_cpsA_psr, score 2.8e-70 663951004969 1 probable transmembrane helix predicted for SATW20_10520 by TMHMM2.0 at aa 7-28 663951004970 Beta-lactamase; Region: Beta-lactamase; pfam00144 663951004971 Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680 663951004972 1 probable transmembrane helix predicted for SATW20_10530 by TMHMM2.0 at aa 7-26 663951004973 HMMPfam hit to PF00144, Beta-lactamase, score 1.8e-59 663951004974 Heme/copper-type cytochrome/quinol oxidase, subunit 4 [Energy production and conversion]; Region: CyoD; COG3125 663951004975 3 probable transmembrane helices predicted for SATW20_10540 by TMHMM2.0 at aa 5-27, 32-54 and 66-85 663951004976 HMMPfam hit to PF03626, COX4_pro, score 8.1e-35 663951004977 Ubiquinol oxidase subunit III subfamily. Ubiquinol oxidase, the terminal oxidase in the respiratory chains of aerobic bacteria, is a multi-chain transmembrane protein located in the cell membrane. It catalyzes the reduction of O2 and simultaneously...; Region: Ubiquinol_oxidase_III; cd02863 663951004978 Subunit I/III interface [polypeptide binding]; other site 663951004979 Subunit III/IV interface [polypeptide binding]; other site 663951004980 5 probable transmembrane helices predicted for SATW20_10550 by TMHMM2.0 at aa 20-42, 62-84, 91-113,133-155 and 176-198 663951004981 HMMPfam hit to PF00510, COX3, score 3.7e-07 663951004982 Heme/copper-type cytochrome/quinol oxidases, subunit 1 [Energy production and conversion]; Region: CyoB; COG0843 663951004983 Ubiquinol oxidase subunit I. Ubiquinol oxidase, the terminal oxidase in the respiratory chains of aerobic bacteria, is a multi-chain transmembrane protein located in the cell membrane. It catalyzes the reduction of O2 and simultaneously pumps protons...; Region: Ubiquinol_Oxidase_I; cd01662 663951004984 D-pathway; other site 663951004985 Putative ubiquinol binding site [chemical binding]; other site 663951004986 Low-spin heme (heme b) binding site [chemical binding]; other site 663951004987 Putative water exit pathway; other site 663951004988 Binuclear center (heme o3/CuB) [ion binding]; other site 663951004989 K-pathway; other site 663951004990 Putative proton exit pathway; other site 663951004991 15 probable transmembrane helices predicted for SATW20_10560 by TMHMM2.0 at aa 15-37, 56-78, 101-123,136-158, 186-208, 228-250, 275-297, 310-332, 342-364,377-399, 414-436, 449-471, 486-508, 587-604 and 608-627 663951004992 HMMPfam hit to PF00115, COX1, score 6.7e-243 663951004993 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 663951004994 PS00077 Heme-copper oxidase catalytic subunit,copper B binding region signature. 663951004995 cytochrome aa3 quinol oxidase, subunit II; Region: QOXA; TIGR01432 663951004996 Cytochrome C oxidase subunit II, periplasmic domain; Region: COX2; pfam00116 663951004997 COX Aromatic Rich Motif; Region: COX_ARM; pfam06481 663951004998 HMMPfam hit to PF06481, COX_ARM, score 5.2e-12 663951004999 HMMPfam hit to PF00116, COX2, score 0.00011 663951005000 3 probable transmembrane helices predicted for SATW20_10570 by TMHMM2.0 at aa 7-26, 41-63 and 84-106 663951005001 HMMPfam hit to PF02790, COX2_TM, score 1.4e-05 663951005002 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 663951005003 Bacterial Ig-like domain (group 3); Region: Big_3; pfam07523 663951005004 bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase; Provisional; Region: PRK14175 663951005005 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain; Region: THF_DHG_CYH; pfam00763 663951005006 NADP binding domain of methylene-tetrahydrofolate dehydrogenase/cyclohydrolase; Region: NAD_bind_m-THF_DH_Cyclohyd; cd01080 663951005007 homodimer interface [polypeptide binding]; other site 663951005008 NADP binding site [chemical binding]; other site 663951005009 substrate binding site [chemical binding]; other site 663951005010 HMMPfam hit to PF02882, THF_DHG_CYH_C, score 1.1e-99 663951005011 HMMPfam hit to PF00763, THF_DHG_CYH, score 3e-58 663951005012 AIR carboxylase; Region: AIRC; cl00310 663951005013 HMMPfam hit to PF00731, AIRC, score 2.7e-71 663951005014 phosphoribosylaminoimidazole carboxylase ATPase subunit; Reviewed; Region: PRK06019 663951005015 Formate/glycerate dehydrogenases, D-specific 2-hydroxy acid dehydrogenases and related dehydrogenases; Region: FDH_GDH_like; cl17240 663951005016 NAD binding site [chemical binding]; other site 663951005017 ATP-grasp domain; Region: ATP-grasp; pfam02222 663951005018 HMMPfam hit to PF02222, ATP-grasp, score 3.2e-60 663951005019 phosphoribosylaminoimidazole-succinocarboxamide synthase; Reviewed; Region: PRK09362 663951005020 bacterial and archaeal 5-aminoimidazole-4-(N-succinylcarboxamide) ribonucleotide (SAICAR) synthase; Region: SAICAR_synt_PurC; cd01415 663951005021 ATP binding site [chemical binding]; other site 663951005022 active site 663951005023 substrate binding site [chemical binding]; other site 663951005024 HMMPfam hit to PF01259, SAICAR_synt, score 3.2e-93 663951005025 PS01058 SAICAR synthetase signature 2. 663951005026 Phosphoribosylformylglycinamidine (FGAM) synthase, PurS component [Nucleotide transport and metabolism]; Region: PurS; COG1828 663951005027 HMMPfam hit to PF02700, PurS, score 2.7e-16 663951005028 phosphoribosylformylglycinamidine synthase I; Provisional; Region: PRK03619 663951005029 Type 1 glutamine amidotransferase (GATase1)-like domain found in Formylglycinamide ribonucleotide amidotransferase; Region: GATase1_FGAR_AT; cd01740 663951005030 putative active site [active] 663951005031 catalytic triad [active] 663951005032 PS00442 Glutamine amidotransferases class-I active site. 663951005033 phosphoribosylformylglycinamidine synthase II; Provisional; Region: PRK01213 663951005034 PurL subunit of the formylglycinamide ribonucleotide amidotransferase (FGAR-AT), first repeat. FGAR-AT catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to formylglycinamidine ribonucleotide (FGAM), ADP; Region: PurL_repeat1; cd02203 663951005035 dimerization interface [polypeptide binding]; other site 663951005036 ATP binding site [chemical binding]; other site 663951005037 PurL subunit of the formylglycinamide ribonucleotide amidotransferase (FGAR-AT), second repeat. FGAR-AT catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to formylglycinamidine ribonucleotide (FGAM), ADP; Region: PurL_repeat2; cd02204 663951005038 dimerization interface [polypeptide binding]; other site 663951005039 ATP binding site [chemical binding]; other site 663951005040 HMMPfam hit to PF00586, AIRS, score 4.6e-52 663951005041 HMMPfam hit to PF02769, AIRS_C, score 6.3e-49 663951005042 HMMPfam hit to PF00586, AIRS, score 1.4e-38 663951005043 HMMPfam hit to PF02769, AIRS_C, score 0.00047 663951005044 amidophosphoribosyltransferase; Provisional; Region: PRK07272 663951005045 Glutamine amidotransferases class-II (GN-AT)_GPAT- type. This domain is found at the N-terminus of glutamine phosphoribosylpyrophosphate (Prpp) amidotransferase (GPATase) . The glutaminase domain catalyzes amide nitrogen transfer from glutamine to the...; Region: GPATase_N; cd00715 663951005046 active site 663951005047 tetramer interface [polypeptide binding]; other site 663951005048 Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223 663951005049 active site 663951005050 PS00443 Glutamine amidotransferases class-II active site. 663951005051 HMMPfam hit to PF00310, GATase_2, score 5.2e-30 663951005052 HMMPfam hit to PF00156, Pribosyltran, score 7e-09 663951005053 PS00103 Purine/pyrimidine phosphoribosyl transferases signature. 663951005054 phosphoribosylaminoimidazole synthetase; Provisional; Region: PRK05385 663951005055 PurM (Aminoimidazole Ribonucleotide [AIR] synthetase), one of eleven enzymes required for purine biosynthesis, catalyzes the conversion of formylglycinamide ribonucleotide (FGAM) and ATP to AIR, ADP, and Pi, the fifth step in de novo purine biosynthesis; Region: PurM; cd02196 663951005056 dimerization interface [polypeptide binding]; other site 663951005057 putative ATP binding site [chemical binding]; other site 663951005058 HMMPfam hit to PF00586, AIRS, score 6.7e-65 663951005059 HMMPfam hit to PF02769, AIRS_C, score 1.5e-50 663951005060 Folate-dependent phosphoribosylglycinamide formyltransferase PurN [Nucleotide transport and metabolism]; Region: PurN; COG0299 663951005061 Phosphoribosylglycinamide formyltransferase (GAR transformylase, GART); Region: FMT_core_GART; cd08645 663951005062 active site 663951005063 substrate binding site [chemical binding]; other site 663951005064 cosubstrate binding site; other site 663951005065 catalytic site [active] 663951005066 HMMPfam hit to PF00551, Formyl_trans_N, score 9.2e-64 663951005067 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; Provisional; Region: purH; PRK00881 663951005068 Inosine monophosphate cyclohydrolase domain. This is the N-terminal domain in the purine biosynthesis pathway protein ATIC (purH). The bifunctional ATIC protein contains a C-terminal ATIC formylase domain that formylates...; Region: IMPCH; cd01421 663951005069 purine monophosphate binding site [chemical binding]; other site 663951005070 dimer interface [polypeptide binding]; other site 663951005071 putative catalytic residues [active] 663951005072 AICARFT/IMPCHase bienzyme; Region: AICARFT_IMPCHas; smart00798 663951005073 AICARFT/IMPCHase bienzyme; Region: AICARFT_IMPCHas; cl03362 663951005074 HMMPfam hit to PF02142, MGS, score 1.1e-59 663951005075 HMMPfam hit to PF01808, AICARFT_IMPCHas, score 8.7e-123 663951005076 Phosphoribosylglycinamide synthetase, N domain; Region: GARS_N; pfam02844 663951005077 phosphoribosylamine--glycine ligase; Provisional; Region: PRK13790 663951005078 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Region: GARS_A; pfam01071 663951005079 Phosphoribosylglycinamide synthetase, C domain; Region: GARS_C; pfam02843 663951005080 HMMPfam hit to PF02844, GARS_N, score 1.5e-43 663951005081 HMMPfam hit to PF01071, GARS_A, score 2.6e-87 663951005082 PS00184 Phosphoribosylglycinamide synthetase signature. 663951005083 HMMPfam hit to PF02843, GARS_C, score 2.7e-26 663951005084 ABC-type cobalt transport system, permease component CbiQ and related transporters [Inorganic ion transport and metabolism]; Region: CbiQ; COG0619 663951005085 6 probable transmembrane helices predicted for SATW20_10710 by TMHMM2.0 at aa 15-34, 39-56, 61-83,114-136, 146-165 and 234-256 663951005086 HMMPfam hit to PF02361, CbiQ, score 3.9e-17 663951005087 ABC-type cobalt transport system, ATPase component [Inorganic ion transport and metabolism]; Region: CbiO; COG1122 663951005088 First domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain1; cd03225 663951005089 Walker A/P-loop; other site 663951005090 ATP binding site [chemical binding]; other site 663951005091 Q-loop/lid; other site 663951005092 ABC transporter signature motif; other site 663951005093 Walker B; other site 663951005094 D-loop; other site 663951005095 H-loop/switch region; other site 663951005096 ABC-type transport system involved in cytochrome c biogenesis, ATPase component [Posttranslational modification, protein turnover, chaperones]; Region: CcmA; COG4133 663951005097 First domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain1; cd03225 663951005098 Walker A/P-loop; other site 663951005099 ATP binding site [chemical binding]; other site 663951005100 Q-loop/lid; other site 663951005101 ABC transporter signature motif; other site 663951005102 Walker B; other site 663951005103 D-loop; other site 663951005104 H-loop/switch region; other site 663951005105 HMMPfam hit to PF00005, ABC_tran, score 5.9e-39 663951005106 PS00017 ATP/GTP-binding site motif A (P-loop). 663951005107 PS00017 ATP/GTP-binding site motif A (P-loop). 663951005108 HMMPfam hit to PF00005, ABC_tran, score 2.9e-33 663951005109 PS00211 ABC transporters family signature. 663951005110 PS00017 ATP/GTP-binding site motif A (P-loop). 663951005111 ABC-type cobalt transport system, predicted permease component [Inorganic ion transport and metabolism]; Region: COG4721 663951005112 5 probable transmembrane helices predicted for SATW20_10730 by TMHMM2.0 at aa 10-31, 47-69, 84-106,113-135 and 145-167 663951005113 10 probable transmembrane helices predicted for SATW20_10750 by TMHMM2.0 at aa 12-34, 69-91, 104-123,128-147, 160-182, 192-214, 309-326, 346-368, 375-397 and 401-423 663951005114 Predicted SAM-dependent methyltransferases [General function prediction only]; Region: COG1092 663951005115 Middle domain of the SAM-dependent methyltransferase RlmI and related proteins; Region: RlmI_M_like; cd11572 663951005116 putative RNA binding site [nucleotide binding]; other site 663951005117 Methyltransferase domain; Region: Methyltransf_26; pfam13659 663951005118 Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367 663951005119 dimerization domain swap beta strand [polypeptide binding]; other site 663951005120 regulatory protein interface [polypeptide binding]; other site 663951005121 active site 663951005122 regulatory phosphorylation site [posttranslational modification]; other site 663951005123 HMMPfam hit to PF00381, PTS-HPr, score 6.1e-54 663951005124 PS00369 PTS HPR component histidine phosphorylation site signature. 663951005125 PS00589 PTS HPR component serine phosphorylation site signature. 663951005126 Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) [Carbohydrate transport and metabolism]; Region: PtsA; COG1080 663951005127 PEP-utilising enzyme, N-terminal; Region: PEP-utilisers_N; pfam05524 663951005128 PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391 663951005129 PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896 663951005130 HMMPfam hit to PF05524, PEP-utilisers_N, score 1.9e-63 663951005131 HMMPfam hit to PF00391, PEP-utilizers, score 4.8e-42 663951005132 PS00370 PEP-utilizing enzymes phosphorylation site signature. 663951005133 HMMPfam hit to PF02896, PEP-utilizers_C, score 2.5e-192 663951005134 PS00742 PEP-utilizing enzymes signature 2. 663951005135 NrdH-redoxin (NrdH) family; NrdH is a small monomeric protein with a conserved redox active CXXC motif within a TRX fold, characterized by a glutaredoxin (GRX)-like sequence and TRX-like activity profile. In vitro, it displays protein disulfide reductase...; Region: NrdH; cd02976 663951005136 catalytic residues [active] 663951005137 HMMPfam hit to PF00462, Glutaredoxin, score 2.8e-08 663951005138 Bacterial Cytochrome Ubiquinol Oxidase; Region: Bac_Ubq_Cox; pfam01654 663951005139 HMMPfam hit to PF01654, Bac_Ubq_Cox, score 1.2e-112 663951005140 9 probable transmembrane helices predicted for SATW20_10810 by TMHMM2.0 at aa 15-37, 58-80, 90-112,124-146, 182-204, 225-242, 322-344, 357-379 and 405-427 663951005141 Cytochrome bd-type quinol oxidase, subunit 2 [Energy production and conversion]; Region: AppB; COG1294 663951005142 9 probable transmembrane helices predicted for SATW20_10820 by TMHMM2.0 at aa 10-32, 52-74, 84-103,116-138, 158-180, 201-223, 233-255, 260-279 and 306-328 663951005143 K+ transport systems, NAD-binding component [Inorganic ion transport and metabolism]; Region: TrkA; COG0569 663951005144 TrkA-N domain; Region: TrkA_N; pfam02254 663951005145 TrkA-C domain; Region: TrkA_C; pfam02080 663951005146 HMMPfam hit to PF02254, TrkA_N, score 4.8e-44 663951005147 HMMPfam hit to PF02080, TrkA_C, score 4.2e-15 663951005148 mRNA degradation ribonucleases J1/J2 (metallo-beta-lactamase superfamily) [Translation, ribosomal structure and biogenesis; Replication, recombination and repair]; Region: COG0595 663951005149 Metallo-beta-lactamase superfamily; Region: Lactamase_B; pfam00753 663951005150 RNA-metabolising metallo-beta-lactamase; Region: RMMBL; pfam07521 663951005151 PS00018 EF-hand calcium-binding domain. 663951005152 HMMPfam hit to PF07521, RMMBL, score 9.4e-14 663951005153 PS01292 Uncharacterized protein family UPF0036 signature. 663951005154 HMMPfam hit to PF00753, Lactamase_B, score 4.9e-29 663951005155 PS00136 Serine proteases, subtilase family, aspartic acid active site. 663951005156 hypothetical protein; Provisional; Region: PRK13667 663951005157 HMMPfam hit to PF07288, DUF1447, score 7.6e-43 663951005158 Polypeptide or peptide deformylase; a family of metalloenzymes that catalyzes the removal of the N-terminal formyl group in a growing polypeptide chain following translation initiation during protein synthesis in prokaryotes. These enzymes utilize Fe(II)...; Region: Pep_deformylase; cd00487 663951005159 active site 663951005160 catalytic residues [active] 663951005161 metal binding site [ion binding]; metal-binding site 663951005162 HMMPfam hit to PF01327, Pep_deformylase, score 6.7e-81 663951005163 Putative cell-wall binding lipoprotein; Region: YkyA; pfam10368 663951005164 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 663951005165 pyruvate dehydrogenase E1 component, alpha subunit; Region: PDH_E1_alph_x; TIGR03181 663951005166 Thiamine pyrophosphate (TPP) family, E1 of PDC_ADC_BCADC subfamily, TPP-binding module; composed of proteins similar to the E1 components of the human pyruvate dehydrogenase complex (PDC), the acetoin dehydrogenase complex (ADC) and the branched chain...; Region: TPP_E1_PDC_ADC_BCADC; cd02000 663951005167 TPP-binding site [chemical binding]; other site 663951005168 tetramer interface [polypeptide binding]; other site 663951005169 heterodimer interface [polypeptide binding]; other site 663951005170 phosphorylation loop region [posttranslational modification] 663951005171 HMMPfam hit to PF00676, E1_dh, score 2.3e-144 663951005172 Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit [Energy production and conversion]; Region: AcoB; COG0022 663951005173 Pyrimidine (PYR) binding domain of the beta subunits of the E1 components of human pyruvate dehydrogenase complex (E1- PDHc) and related proteins; Region: TPP_PYR_E1-PDHc-beta_like; cd07036 663951005174 alpha subunit interface [polypeptide binding]; other site 663951005175 TPP binding site [chemical binding]; other site 663951005176 heterodimer interface [polypeptide binding]; other site 663951005177 Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780 663951005178 HMMPfam hit to PF02779, Transket_pyr, score 5.7e-51 663951005179 HMMPfam hit to PF02780, Transketolase_C, score 4.5e-54 663951005180 branched-chain alpha-keto acid dehydrogenase subunit E2; Reviewed; Region: PRK11856 663951005181 Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849 663951005182 E3 interaction surface; other site 663951005183 lipoyl attachment site [posttranslational modification]; other site 663951005184 e3 binding domain; Region: E3_binding; pfam02817 663951005185 2-oxoacid dehydrogenases acyltransferase (catalytic domain); Region: 2-oxoacid_dh; pfam00198 663951005186 HMMPfam hit to PF00364, Biotin_lipoyl, score 1.7e-32 663951005187 PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 663951005188 HMMPfam hit to PF02817, E3_binding, score 7.6e-19 663951005189 HMMPfam hit to PF00198, 2-oxoacid_dh, score 6.5e-138 663951005190 dihydrolipoamide dehydrogenase; Reviewed; Region: PRK06416 663951005191 NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450 663951005192 Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070 663951005193 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852 663951005194 HMMPfam hit to PF07992, Pyr_redox_2, score 1.1e-74 663951005195 PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 663951005196 HMMPfam hit to PF00070, Pyr_redox, score 3.3e-33 663951005197 HMMPfam hit to PF02852, Pyr_redox_dim, score 3.2e-53 663951005198 hypothetical protein; Provisional; Region: PRK04387 663951005199 HMMPfam hit to PF05256, UPF0223, score 2.6e-66 663951005200 Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396 663951005201 Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093 663951005202 non-specific DNA binding site [nucleotide binding]; other site 663951005203 salt bridge; other site 663951005204 sequence-specific DNA binding site [nucleotide binding]; other site 663951005205 Cupin domain; Region: Cupin_2; pfam07883 663951005206 HMMPfam hit to PF01381, HTH_3, score 2.9e-16 663951005207 Predicted helix-turn-helix motif with score 1972.000, SD 5.90 at aa 16-37, sequence LTQEELAERTDLSKGYISQIES 663951005208 HMMPfam hit to PF07883, Cupin_2, score 1.5e-07 663951005209 ABC-type spermidine/putrescine transport systems, ATPase components [Amino acid transport and metabolism]; Region: PotA; COG3842 663951005210 ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201 663951005211 Walker A/P-loop; other site 663951005212 ATP binding site [chemical binding]; other site 663951005213 Q-loop/lid; other site 663951005214 ABC transporter signature motif; other site 663951005215 Walker B; other site 663951005216 D-loop; other site 663951005217 H-loop/switch region; other site 663951005218 TOBE domain; Region: TOBE_2; pfam08402 663951005219 HMMPfam hit to PF00005, ABC_tran, score 3.1e-58 663951005220 PS00017 ATP/GTP-binding site motif A (P-loop). 663951005221 PS00211 ABC transporters family signature. 663951005222 HMMPfam hit to PF08402, TOBE_2, score 2.5e-12 663951005223 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 663951005224 putative PBP binding loops; other site 663951005225 dimer interface [polypeptide binding]; other site 663951005226 ABC-ATPase subunit interface; other site 663951005227 6 probable transmembrane helices predicted for SATW20_10950 by TMHMM2.0 at aa 7-29, 60-82, 89-111,131-153, 193-215 and 235-257 663951005228 HMMPfam hit to PF00528, BPD_transp_1, score 0.0022 663951005229 PS00402 Binding-protein-dependent transport systems inner membrane comp. sign. 663951005230 ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177 663951005231 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 663951005232 dimer interface [polypeptide binding]; other site 663951005233 conserved gate region; other site 663951005234 putative PBP binding loops; other site 663951005235 ABC-ATPase subunit interface; other site 663951005236 6 probable transmembrane helices predicted for SATW20_10960 by TMHMM2.0 at aa 7-29, 62-84, 97-119,129-151, 175-197 and 236-258 663951005237 HMMPfam hit to PF00528, BPD_transp_1, score 4.9e-15 663951005238 Spermidine/putrescine-binding periplasmic protein [Amino acid transport and metabolism]; Region: PotD; COG0687 663951005239 Bacterial extracellular solute-binding protein; Region: SBP_bac_1; cl17199 663951005240 1 probable transmembrane helix predicted for SATW20_10970 by TMHMM2.0 at aa 7-25 663951005241 HMMPfam hit to PF01547, SBP_bac_1, score 4e-12 663951005242 Protein of unknown function (DUF4064); Region: DUF4064; pfam13273 663951005243 ABC-2 family transporter protein; Region: ABC2_membrane_4; pfam12730 663951005244 3 probable transmembrane helices predicted for SATW20_10980 by TMHMM2.0 at aa 20-42, 84-106 and 113-147 663951005245 Protein of unknown function (DUF4064); Region: DUF4064; pfam13273 663951005246 3 probable transmembrane helices predicted for SATW20_10990 by TMHMM2.0 at aa 7-29, 61-83 and 90-121 663951005247 manganese transport protein MntH; Reviewed; Region: PRK00701 663951005248 Natural resistance-associated macrophage protein; Region: Nramp; pfam01566 663951005249 10 probable transmembrane helices predicted for SATW20_11000 by TMHMM2.0 at aa 33-55, 59-81, 102-124,139-161, 168-190, 210-232, 263-285, 305-327, 384-406 and 421-443 663951005250 HMMPfam hit to PF01566, Nramp, score 6.5e-143 663951005251 Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4493 663951005252 Protein of unknown function (DUF1054); Region: DUF1054; pfam06335 663951005253 HMMPfam hit to PF06335, DUF1054, score 7.2e-155 663951005254 Inositol-monophosphatase-like domains. This family of phosphatases is dependent on bivalent metal ions such as Mg++, and many members are inhibited by Li+ (which is thought to displace a bivalent ion in the active site). Substrates include fructose-1; Region: IMPase_like; cd01637 663951005255 Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family [Carbohydrate transport and metabolism]; Region: SuhB; COG0483 663951005256 active site 663951005257 HMMPfam hit to PF00459, Inositol_P, score 1.8e-63 663951005258 PS00629 Inositol monophosphatase family signature 1. 663951005259 2 probable transmembrane helices predicted for SATW20_11030 by TMHMM2.0 at aa 9-31 and 35-52 663951005260 Predicted membrane GTPase involved in stress response [Signal transduction mechanisms]; Region: TypA; COG1217 663951005261 Tyrosine phosphorylated protein A (TypA)/BipA family belongs to ribosome-binding GTPases; Region: TypA_BipA; cd01891 663951005262 G1 box; other site 663951005263 putative GEF interaction site [polypeptide binding]; other site 663951005264 GTP/Mg2+ binding site [chemical binding]; other site 663951005265 Switch I region; other site 663951005266 G2 box; other site 663951005267 G3 box; other site 663951005268 Switch II region; other site 663951005269 G4 box; other site 663951005270 G5 box; other site 663951005271 BipA_TypA_II: domain II of BipA (also called TypA) having homology to domain II of the elongation factors (EFs) EF-G and EF-Tu. BipA is a highly conserved protein with global regulatory properties in Escherichia coli. BipA is phosphorylated on a...; Region: BipA_TypA_II; cd03691 663951005272 BipA_TypA_C: a C-terminal portion of BipA or TypA having homology to the C terminal domains of the elongation factors EF-G and EF-2. A member of the ribosome binding GTPase superfamily, BipA is widely distributed in bacteria and plants. BipA is a highly...; Region: BipA_TypA_C; cd03710 663951005273 HMMPfam hit to PF00009, GTP_EFTU, score 3.5e-71 663951005274 PS00017 ATP/GTP-binding site motif A (P-loop). 663951005275 PS00301 GTP-binding elongation factors signature. 663951005276 HMMPfam hit to PF03144, GTP_EFTU_D2, score 4.2e-15 663951005277 HMMPfam hit to PF00679, EFG_C, score 7.7e-21 663951005278 Uncharacterized protein conserved in bacteria (DUF2197); Region: DUF2197; pfam09963 663951005279 hypothetical protein; Provisional; Region: PRK13666 663951005280 HMMPfam hit to PF07408, DUF1507, score 9.3e-53 663951005281 Bacterial cell division membrane protein [Cell division and chromosome partitioning]; Region: FtsW; COG0772 663951005282 HMMPfam hit to PF01098, FTSW_RODA_SPOVE, score 1.7e-93 663951005283 10 probable transmembrane helices predicted for SATW20_11080 by TMHMM2.0 at aa 20-42, 66-88, 93-111,126-148, 160-177, 181-203, 208-230, 288-313, 326-348 and 363-385 663951005284 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 663951005285 pyruvate carboxylase; Reviewed; Region: PRK12999 663951005286 Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289 663951005287 Carbamoyl-phosphate synthase L chain, ATP binding domain; Region: CPSase_L_D2; pfam02786 663951005288 Biotin carboxylase C-terminal domain; Region: Biotin_carb_C; smart00878 663951005289 Pyruvate carboxylase and Transcarboxylase 5S, carboxyltransferase domain; Region: DRE_TIM_PC_TC_5S; cd07937 663951005290 active site 663951005291 catalytic residues [active] 663951005292 metal binding site [ion binding]; metal-binding site 663951005293 homodimer binding site [polypeptide binding]; other site 663951005294 The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850 663951005295 carboxyltransferase (CT) interaction site; other site 663951005296 biotinylation site [posttranslational modification]; other site 663951005297 HMMPfam hit to PF00289, CPSase_L_chain, score 4.7e-39 663951005298 HMMPfam hit to PF02786, CPSase_L_D2, score 9.4e-105 663951005299 PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 663951005300 PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 663951005301 HMMPfam hit to PF02785, Biotin_carb_C, score 1.2e-57 663951005302 HMMPfam hit to PF00682, HMGL-like, score 5.3e-15 663951005303 HMMPfam hit to PF02436, PYC_OADA, score 4.9e-98 663951005304 HMMPfam hit to PF00364, Biotin_lipoyl, score 3.8e-24 663951005305 Uncharacterized protein required for cytochrome oxidase assembly [Posttranslational modification, protein turnover, chaperones]; Region: CtaA; COG1612 663951005306 Cytochrome oxidase assembly protein; Region: COX15-CtaA; pfam02628 663951005307 HMMPfam hit to PF02628, COX15-CtaA, score 1.3e-42 663951005308 8 probable transmembrane helices predicted for SATW20_11100 by TMHMM2.0 at aa 7-29, 65-87, 94-116,121-143, 164-181, 211-233, 245-267 and 271-293 663951005309 protoheme IX farnesyltransferase; Provisional; Region: PRK04375 663951005310 UbiA prenyltransferase family; Region: UbiA; pfam01040 663951005311 8 probable transmembrane helices predicted for SATW20_11110 by TMHMM2.0 at aa 22-44, 54-76, 104-123,127-144, 149-171, 175-197, 227-260 and 280-302 663951005312 HMMPfam hit to PF01040, UbiA, score 1.6e-69 663951005313 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 663951005314 Predicted membrane protein [Function unknown]; Region: COG2322 663951005315 HMMPfam hit to PF04238, DUF420, score 8.6e-75 663951005316 4 probable transmembrane helices predicted for SATW20_11120 by TMHMM2.0 at aa 5-27, 39-61, 76-98 and 118-140 663951005317 Uncharacterized protein with SCP/PR1 domains [Function unknown]; Region: COG2340 663951005318 SCP_bacterial: SCP-like extracellular protein domain, as found in bacteria and archaea. The wider family of SCP containing proteins includes plant pathogenesis-related protein 1 (PR-1), CRISPs, mammalian cysteine-rich secretory proteins, and allergen 5...; Region: SCP_bacterial; cd05379 663951005319 1 probable transmembrane helix predicted for SATW20_11130 by TMHMM2.0 at aa 5-24 663951005320 HMMPfam hit to PF00188, SCP, score 5.9e-21 663951005321 Regulatory protein involved in competence development and sporulation [Replication, recombination and repair; Signal transduction mechanisms]; Region: COG3679 663951005322 HMMPfam hit to PF07050, DUF1333, score 1.1e-101 663951005323 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 663951005324 Glycerophosphoryl diester phosphodiesterase [Energy production and conversion]; Region: UgpQ; COG0584 663951005325 Glycerophosphodiester phosphodiesterase domain of Streptomyces coelicolor cytoplasmic phosphodiesterases UgpQ2 and similar proteins; Region: GDPD_cytoplasmic_ScUgpQ2_like; cd08561 663951005326 putative active site [active] 663951005327 catalytic site [active] 663951005328 putative metal binding site [ion binding]; other site 663951005329 HMMPfam hit to PF03009, GDPD, score 6.4e-28 663951005330 1 probable transmembrane helix predicted for SATW20_11150 by TMHMM2.0 at aa 7-25 663951005331 Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4471 663951005332 Conserved hypothetical protein 95; Region: Cons_hypoth95; pfam03602 663951005333 S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440 663951005334 S-adenosylmethionine binding site [chemical binding]; other site 663951005335 HMMPfam hit to PF03602, Cons_hypoth95, score 1.3e-84 663951005336 PS00092 N-6 Adenine-specific DNA methylases signature. 663951005337 phosphopantetheine adenylyltransferase; Provisional; Region: coaD; PRK00168 663951005338 Phosphopantetheine adenylyltransferase; Region: PPAT; cd02163 663951005339 active site 663951005340 (T/H)XGH motif; other site 663951005341 HMMPfam hit to PF01467, CTP_transf_2, score 1.3e-30 663951005342 HIGH Nucleotidyl Transferase; Region: HIGH_NTase1; pfam05636 663951005343 hypothetical protein; Provisional; Region: PRK13670 663951005344 HMMPfam hit to PF05636, DUF795, score 1e-233 663951005345 Predicted metal-binding, possibly nucleic acid-binding protein [General function prediction only]; Region: COG1399 663951005346 HMMPfam hit to PF02620, DUF177, score 3.8e-52 663951005347 50S ribosomal protein L32; Reviewed; Region: rpmF; PRK12286 663951005348 HMMPfam hit to PF01783, Ribosomal_L32p, score 9.2e-32 663951005349 heme uptake protein IsdB; Region: IsdB; TIGR03657 663951005350 YSIRK type signal peptide; Region: YSIRK_signal; pfam04650 663951005351 NEAr Transporter domain; Region: NEAT; smart00725 663951005352 NEAr Transport domain, a component of cell surface proteins; Region: NEAT; cd06920 663951005353 heme-binding site [chemical binding]; other site 663951005354 Gram positive anchor; Region: Gram_pos_anchor; pfam00746 663951005355 HMMPfam hit to PF00746, Gram_pos_anchor, score 2e-09 663951005356 1 probable transmembrane helix predicted for SATW20_11230 by TMHMM2.0 at aa 622-639 663951005357 PS00343 Gram-positive cocci surface proteins 'anchoring' hexapeptide. 663951005358 HMMPfam hit to PF05031, NEAT, score 1.5e-40 663951005359 HMMPfam hit to PF05031, NEAT, score 3e-28 663951005360 HMMPfam hit to PF04650, YSIRK_signal, score 1.8e-09 663951005361 Cell surface protein [Cell envelope biogenesis, outer membrane]; Region: COG5386 663951005362 NEAr Transport domain, a component of cell surface proteins; Region: NEAT; cd06920 663951005363 heme-binding site [chemical binding]; other site 663951005364 HMMPfam hit to PF00746, Gram_pos_anchor, score 2.1e-09 663951005365 1 probable transmembrane helix predicted for SATW20_11240 by TMHMM2.0 at aa 325-344 663951005366 HMMPfam hit to PF05031, NEAT, score 4.9e-44 663951005367 heme uptake protein IsdC; Region: IsdC; TIGR03656 663951005368 NEAr Transport domain, a component of cell surface proteins; Region: NEAT; cd06920 663951005369 heme-binding site [chemical binding]; other site 663951005370 sortase B signal domain, NPQTN class; Region: srtB_sig_NPQTN; TIGR03068 663951005371 2 probable transmembrane helices predicted for SATW20_11250 by TMHMM2.0 at aa 7-29 and 196-218 663951005372 HMMPfam hit to PF05031, NEAT, score 6.6e-46 663951005373 2 probable transmembrane helices predicted for SATW20_11260 by TMHMM2.0 at aa 13-32 and 329-351 663951005374 Helical backbone metal receptor (TroA-like domain). These proteins have been shown to function in the ABC transport of ferric siderophores and metal ions such as Mn2+, Fe3+, Cu2+ and/or Zn2+. Their ligand binding site is formed in the interface between...; Region: TroA-like; cl00262 663951005375 Periplasmic binding protein; Region: Peripla_BP_2; pfam01497 663951005376 intersubunit interface [polypeptide binding]; other site 663951005377 HMMPfam hit to PF01497, Peripla_BP_2, score 2.8e-28 663951005378 iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577 663951005379 Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550 663951005380 ABC-ATPase subunit interface; other site 663951005381 dimer interface [polypeptide binding]; other site 663951005382 putative PBP binding regions; other site 663951005383 8 probable transmembrane helices predicted for SATW20_11280 by TMHMM2.0 at aa 9-31, 60-82, 112-134,138-160, 180-202, 230-252, 264-286 and 296-315 663951005384 HMMPfam hit to PF01032, FecCD, score 8.1e-69 663951005385 Sortase B (SrtB) or subfamily-2 sortases are membrane cysteine transpeptidases found in gram-positive bacteria that anchor surface proteins to peptidoglycans of the bacterial cell wall envelope. This involves a transpeptidation reaction in which the...; Region: Sortase_B_2; cd05826 663951005386 active site 663951005387 catalytic site [active] 663951005388 1 probable transmembrane helix predicted for SATW20_11290 by TMHMM2.0 at aa 7-29 663951005389 HMMPfam hit to PF07170, Sortase_B, score 1.2e-129 663951005390 heme-degrading monooxygenase IsdG; Provisional; Region: PRK13312 663951005391 HMMPfam hit to PF03992, ABM, score 4.6e-09 663951005392 rRNA methylases [Translation, ribosomal structure and biogenesis]; Region: SpoU; COG0566 663951005393 RNA 2'-O ribose methyltransferase substrate binding; Region: SpoU_sub_bind; pfam08032 663951005394 SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588 663951005395 HMMPfam hit to PF08032, SpoU_sub_bind, score 6.6e-16 663951005396 HMMPfam hit to PF00588, SpoU_methylase, score 1.1e-50 663951005397 phenylalanyl-tRNA synthetase subunit alpha; Validated; Region: pheS; PRK00488 663951005398 Aminoacyl tRNA synthetase class II, N-terminal domain; Region: Phe_tRNA-synt_N; pfam02912 663951005399 Phenylalanyl-tRNA synthetase (PheRS) alpha chain catalytic core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure and the presence of three characteristic sequence motifs. This domain is primarily responsible...; Region: PheRS_alpha_core; cd00496 663951005400 dimer interface [polypeptide binding]; other site 663951005401 motif 1; other site 663951005402 active site 663951005403 motif 2; other site 663951005404 motif 3; other site 663951005405 HMMPfam hit to PF02912, Phe_tRNA-synt_N, score 3.5e-34 663951005406 HMMPfam hit to PF01409, tRNA-synt_2d, score 4.4e-180 663951005407 PS00179 Aminoacyl-transfer RNA synthetases class-II signature 1. 663951005408 PS00225 Crystallins beta and gamma 'Greek key' motif signature. 663951005409 phenylalanyl-tRNA synthetase subunit beta; Reviewed; Region: pheT; PRK00629 663951005410 tRNA-binding-domain-containing prokaryotic phenylalanly tRNA synthetase (PheRS) beta chain. PheRS aminoacylate phenylalanine transfer RNAs (tRNAphe). PheRSs belong structurally to class II aminoacyl tRNA synthetases (aaRSs) but, as they aminoacylate...; Region: tRNA_bind_bactPheRS; cd02796 663951005411 putative tRNA-binding site [nucleotide binding]; other site 663951005412 B3/4 domain; Region: B3_4; pfam03483 663951005413 tRNA synthetase B5 domain; Region: B5; smart00874 663951005414 Phenylalanyl-tRNA synthetase (PheRS) beta chain core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure. While class II aaRSs generally aminoacylate the 3'-OH ribose of the appropriate tRNA, PheRS is an...; Region: PheRS_beta_core; cd00769 663951005415 dimer interface [polypeptide binding]; other site 663951005416 motif 1; other site 663951005417 motif 3; other site 663951005418 motif 2; other site 663951005419 Ferredoxin-fold anticodon binding domain; Region: FDX-ACB; pfam03147 663951005420 HMMPfam hit to PF01588, tRNA_bind, score 2.7e-31 663951005421 HMMPfam hit to PF03483, B3_4, score 2.4e-98 663951005422 HMMPfam hit to PF03484, B5, score 8.7e-29 663951005423 HMMPfam hit to PF03147, FDX-ACB, score 1.1e-28 663951005424 ribonuclease HIII; Provisional; Region: PRK00996 663951005425 Domain of unknown function (DUF3378); Region: DUF3378; pfam11858 663951005426 bacterial Ribonuclease HIII-like; Region: RNase_HII_bacteria_HIII_like; cd06590 663951005427 RNA/DNA hybrid binding site [nucleotide binding]; other site 663951005428 active site 663951005429 HMMPfam hit to PF01351, RNase_HII, score 3.7e-47 663951005430 Cell division protein ZapA; Region: ZapA; cl01146 663951005431 HMMPfam hit to PF05164, ZapA, score 7.1e-28 663951005432 Uncharacterized membrane protein, required for colicin V production [General function prediction only]; Region: CvpA; COG1286 663951005433 Colicin V production protein; Region: Colicin_V; pfam02674 663951005434 HMMPfam hit to PF02674, Colicin_V, score 2.2e-62 663951005435 4 probable transmembrane helices predicted for SATW20_11360 by TMHMM2.0 at aa 5-24, 80-102, 117-139 and 152-171 663951005436 hypothetical protein; Provisional; Region: PRK08609 663951005437 Nucleotidyltransferase (NT) domain of family X DNA Polymerases; Region: NT_POLXc; cd00141 663951005438 active site 663951005439 primer binding site [nucleotide binding]; other site 663951005440 NTP binding site [chemical binding]; other site 663951005441 metal binding triad [ion binding]; metal-binding site 663951005442 Polymerase and Histidinol Phosphatase domain of bacterial polymerase X; Region: PHP_PolX; cd07436 663951005443 active site 663951005444 HMMPfam hit to PF02811, PHP, score 9.4e-34 663951005445 recombination and DNA strand exchange inhibitor protein; Reviewed; Region: PRK00409 663951005446 MutS domain III; Region: MutS_III; pfam05192 663951005447 ATP-binding cassette domain of MutS2; Region: ABC_MutS2; cd03280 663951005448 Walker A/P-loop; other site 663951005449 ATP binding site [chemical binding]; other site 663951005450 Q-loop/lid; other site 663951005451 ABC transporter signature motif; other site 663951005452 Walker B; other site 663951005453 D-loop; other site 663951005454 H-loop/switch region; other site 663951005455 Smr domain; Region: Smr; pfam01713 663951005456 PS00591 Glycosyl hydrolases family 10 active site. 663951005457 HMMPfam hit to PF00488, MutS_V, score 7e-16 663951005458 PS00017 ATP/GTP-binding site motif A (P-loop). 663951005459 HMMPfam hit to PF01713, Smr, score 6.2e-34 663951005460 TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947 663951005461 Thioredoxin-like; Region: Thioredoxin_8; pfam13905 663951005462 catalytic residues [active] 663951005463 HMMPfam hit to PF00085, Thioredoxin, score 1.1e-42 663951005464 PS00194 Thioredoxin family active site. 663951005465 excinuclease ABC subunit C; Validated; Region: uvrC; PRK00558 663951005466 Catalytic GIY-YIG domain of nucleotide excision repair endonucleases UvrC, Cho, and similar proteins; Region: GIY-YIG_UvrC_Cho; cd10434 663951005467 GIY-YIG motif/motif A; other site 663951005468 active site 663951005469 catalytic site [active] 663951005470 putative DNA binding site [nucleotide binding]; other site 663951005471 metal binding site [ion binding]; metal-binding site 663951005472 UvrB/uvrC motif; Region: UVR; pfam02151 663951005473 UvrC Helix-hairpin-helix N-terminal; Region: UvrC_HhH_N; pfam08459 663951005474 HMMPfam hit to PF01541, GIY-YIG, score 1e-33 663951005475 HMMPfam hit to PF02151, UVR, score 2.5e-10 663951005476 HMMPfam hit to PF08459, UvrC_HhH_N, score 1.9e-85 663951005477 Succinate:quinone oxidoreductase (SQR) Type B subfamily 1, transmembrane subunit; composed of proteins similar to Bacillus subtilis SQR. SQR catalyzes the oxidation of succinate to fumarate coupled to the reduction of quinone to quinol. Bacillus subtilis...; Region: SQR_TypeB_1_TM; cd03497 663951005478 putative Iron-sulfur protein interface [polypeptide binding]; other site 663951005479 succinate dehydrogenase (or fumarate reductase) cytochrome b subunit, b558 family; Region: sdhC_b558_fam; TIGR02046 663951005480 proximal heme binding site [chemical binding]; other site 663951005481 distal heme binding site [chemical binding]; other site 663951005482 putative dimer interface [polypeptide binding]; other site 663951005483 5 probable transmembrane helices predicted for SATW20_11410 by TMHMM2.0 at aa 13-32, 52-74, 95-117,145-167 and 180-202 663951005484 succinate dehydrogenase flavoprotein subunit; Reviewed; Region: sdhA; PRK08641 663951005485 L-aspartate oxidase; Provisional; Region: PRK06175 663951005486 Fumarate reductase flavoprotein C-term; Region: Succ_DH_flav_C; pfam02910 663951005487 HMMPfam hit to PF00890, FAD_binding_2, score 1.4e-113 663951005488 PS00504 Fumarate reductase / succinate dehydrogenase FAD-binding site. 663951005489 HMMPfam hit to PF02910, Succ_DH_flav_C, score 4.4e-52 663951005490 succinate dehydrogenase iron-sulfur subunit; Reviewed; Region: sdhB; PRK08640 663951005491 2Fe-2S iron-sulfur cluster binding domain; Region: Fer2_3; pfam13085 663951005492 HMMPfam hit to PF00037, Fer4, score 0.0022 663951005493 PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature. 663951005494 glutamate racemase; Provisional; Region: PRK00865 663951005495 HMMPfam hit to PF01177, Asp_Glu_race, score 2.8e-100 663951005496 PS00923 Aspartate and glutamate racemases signature 1. 663951005497 PS00924 Aspartate and glutamate racemases signature 2. 663951005498 NTPase/HAM1. This family consists of the HAM1 protein and pyrophosphate-releasing xanthosine/ inosine triphosphatase. HAM1 protects the cell against mutagenesis by the base analog 6-N-hydroxylaminopurine (HAP) in E. Coli and S. cerevisiae. A...; Region: HAM1; cd00515 663951005499 active site 663951005500 dimerization interface [polypeptide binding]; other site 663951005501 HMMPfam hit to PF01725, Ham1p_like, score 1.3e-73 663951005502 Escherichia coli YfcE and related proteins, metallophosphatase domain; Region: MPP_YfcE; cd00841 663951005503 active site 663951005504 metal binding site [ion binding]; metal-binding site 663951005505 homotetramer interface [polypeptide binding]; other site 663951005506 HMMPfam hit to PF00149, Metallophos, score 1.1e-05 663951005507 Extracellular fibrinogen binding protein C terminal; Region: efb-c; pfam12199 663951005508 formyl peptide receptor-like 1 inhibitory protein; Reviewed; Region: PRK13033 663951005509 5 probable transmembrane helices predicted for SATW20_11490 by TMHMM2.0 at aa 2-20, 35-57, 64-86, 101-120 and 141-160 663951005510 Extracellular fibrinogen binding protein C terminal; Region: efb-c; pfam12199 663951005511 Staphylococcal complement inhibitor SCIN; Region: CompInhib_SCIN; pfam11546 663951005512 1 probable transmembrane helix predicted for SATW20_11520 by TMHMM2.0 at aa 30-52 663951005513 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 663951005514 3 probable transmembrane helices predicted for SATW20_11530 by TMHMM2.0 at aa 2-24, 29-51 and 58-80 663951005515 beta-channel forming cytolysin; Region: hlyII; TIGR01002 663951005516 HMMPfam hit to PF07968, Leukocidin, score 2.5e-53 663951005517 PS00274 Aerolysin type toxins signature. 663951005518 Transposase, Mutator family; Region: Transposase_mut; pfam00872 663951005519 MULE transposase domain; Region: MULE; pfam10551 663951005520 HMMPfam hit to PF00872, Transposase_mut, score 9.8e-228 663951005521 PS01007 Transposases, Mutator family, signature. 663951005522 1 probable transmembrane helix predicted for SATW20_11570 by TMHMM2.0 at aa 5-36 663951005523 superantigen-like protein; Reviewed; Region: PRK13350 663951005524 Staphylococcal/Streptococcal toxin, beta-grasp domain; Region: Stap_Strp_tox_C; pfam02876 663951005525 HMMPfam hit to PF02876, Stap_Strp_tox_C, score 0.057 663951005526 PS00278 Staphyloccocal enterotoxin/Streptococcal pyrogenic exotoxin signature 2. 663951005527 superantigen-like protein; Reviewed; Region: PRK13349 663951005528 Staphylococcal/Streptococcal toxin, beta-grasp domain; Region: Stap_Strp_tox_C; pfam02876 663951005529 HMMPfam hit to PF02876, Stap_Strp_tox_C, score 0.0017 663951005530 PS00278 Staphyloccocal enterotoxin/Streptococcal pyrogenic exotoxin signature 2. 663951005531 superantigen-like protein; Reviewed; Region: PRK13043 663951005532 Staphylococcal/Streptococcal toxin, beta-grasp domain; Region: Stap_Strp_tox_C; pfam02876 663951005533 HMMPfam hit to PF02876, Stap_Strp_tox_C, score 0.0015 663951005534 PS00278 Staphyloccocal enterotoxin/Streptococcal pyrogenic exotoxin signature 2. 663951005535 ornithine carbamoyltransferase; Provisional; Region: PRK04284 663951005536 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729 663951005537 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185 663951005538 HMMPfam hit to PF02729, OTCace_N, score 1.9e-68 663951005539 PS00097 Aspartate and ornithine carbamoyltransferases signature. 663951005540 HMMPfam hit to PF00185, OTCace, score 4.9e-79 663951005541 carbamate kinase; Reviewed; Region: PRK12686 663951005542 AAK_CK: Carbamate kinase (CK) catalyzes both the ATP-phosphorylation of carbamate and carbamoyl phosphate (CP) utilization with the production of ATP from ADP and CP. Both CK (this CD) and nonhomologous CP synthetase synthesize carbamoyl phosphate, an...; Region: AAK_CK; cd04235 663951005543 putative substrate binding site [chemical binding]; other site 663951005544 nucleotide binding site [chemical binding]; other site 663951005545 nucleotide binding site [chemical binding]; other site 663951005546 homodimer interface [polypeptide binding]; other site 663951005547 HMMPfam hit to PF00696, AA_kinase, score 7.1e-85 663951005548 PS00017 ATP/GTP-binding site motif A (P-loop). 663951005549 Predicted membrane protein [Function unknown]; Region: COG1288 663951005550 C4-dicarboxylate anaerobic carrier; Region: DcuC; pfam03606 663951005551 HMMPfam hit to PF03606, DcuC, score 1.5e-263 663951005552 13 probable transmembrane helices predicted for SATW20_11630 by TMHMM2.0 at aa 21-43, 127-149, 162-184,189-211, 213-235, 245-267, 308-325, 329-351, 364-386,406-428, 435-457, 462-481 and 494-516 663951005553 PS00012 Phosphopantetheine attachment site. 663951005554 2 probable transmembrane helices predicted for SATW20_11640 by TMHMM2.0 at aa 7-29 and 44-61 663951005555 Tellurite resistance protein and related permeases [Inorganic ion transport and metabolism]; Region: TehA; COG1275 663951005556 C4-dicarboxylate transporters of the Tellurite-resistance/Dicarboxylate Transporter (TDT) family; Region: TDT_C4-dicarb_trans; cd09325 663951005557 gating phenylalanine in ion channel; other site 663951005558 10 probable transmembrane helices predicted for SATW20_11650 by TMHMM2.0 at aa 7-24, 29-51, 64-86, 96-118,130-149, 153-175, 187-209, 214-233, 246-268 and 278-300 663951005559 HMMPfam hit to PF03595, C4dic_mal_tran, score 9.7e-80 663951005560 Predicted helix-turn-helix motif with score 1183.000, SD 3.22 at aa 13-34, sequence LSSLHISKQTGVPQSTIHRMRK 663951005561 Staphylococcus haemolytic protein; Region: Staph_haemo; pfam05480 663951005562 HMMPfam hit to PF05480, Staph_haemo, score 1.8e-25 663951005563 PS00572 Glycosyl hydrolases family 1 active site. 663951005564 Staphylococcus haemolytic protein; Region: Staph_haemo; pfam05480 663951005565 HMMPfam hit to PF05480, Staph_haemo, score 1.4e-26 663951005566 HAD superfamily (subfamily IA) hydrolase, TIGR02254; Region: YjjG/YfnB 663951005567 Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427 663951005568 motif II; other site 663951005569 HMMPfam hit to PF00702, Hydrolase, score 3.4e-18 663951005570 hypothetical protein; Provisional; Region: PRK13688 663951005571 Acetyltransferase (GNAT) domain; Region: Acetyltransf_7; pfam13508 663951005572 Coenzyme A binding pocket [chemical binding]; other site 663951005573 HMMPfam hit to PF00583, Acetyltransf_1, score 0.00048 663951005574 Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4365 663951005575 bacillithiol biosynthesis cysteine-adding enzyme BshC; Region: thiol_BshC; TIGR03998 663951005576 Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2001 663951005577 MraZ protein; Region: MraZ; pfam02381 663951005578 MraZ protein; Region: MraZ; pfam02381 663951005579 HMMPfam hit to PF02381, MraZ, score 5.8e-32 663951005580 HMMPfam hit to PF02381, MraZ, score 2.3e-35 663951005581 Predicted S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis [Cell envelope biogenesis, outer membrane]; Region: COG0275 663951005582 MraW methylase family; Region: Methyltransf_5; pfam01795 663951005583 HMMPfam hit to PF01795, Methyltransf_5, score 1.2e-207 663951005584 Protein required for the initiation of cell division [Cell division and chromosome partitioning]; Region: FtsL; COG4839 663951005585 1 probable transmembrane helix predicted for SATW20_11740 by TMHMM2.0 at aa 46-65 663951005586 HMMPfam hit to PF04977, DivIC, score 2.1e-15 663951005587 Cell division protein FtsI/penicillin-binding protein 2 [Cell envelope biogenesis, outer membrane]; Region: FtsI; COG0768 663951005588 Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717 663951005589 Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905 663951005590 PASTA domain of PBP2x-like proteins, first repeat. Penicillin-binding proteins (PBPs) are the major targets for beta-lactam antibiotics, like penicillins and cephalosporins. Beta-lactam antibiotics specifically inhibit transpeptidase activity by...; Region: PASTA_Pbp2x-like_1; cd06576 663951005591 PASTA domain of PBP2x-like proteins, second repeat. Penicillin-binding proteins (PBPs) are the major targets for beta-lactam antibiotics, like penicillins and cephalosporins. Beta-lactam antibiotics specifically inhibit transpeptidase activity by...; Region: PASTA_Pbp2x-like_2; cd06575 663951005592 1 probable transmembrane helix predicted for SATW20_11750 by TMHMM2.0 at aa 13-35 663951005593 HMMPfam hit to PF03717, PBP_dimer, score 2.2e-57 663951005594 HMMPfam hit to PF00905, Transpeptidase, score 3.8e-115 663951005595 PS00017 ATP/GTP-binding site motif A (P-loop). 663951005596 HMMPfam hit to PF03793, PASTA, score 2.8e-11 663951005597 HMMPfam hit to PF03793, PASTA, score 4.9e-10 663951005598 phospho-N-acetylmuramoyl-pentapeptide-transferase; Provisional; Region: mraY; PRK00108 663951005599 Phospho-N-acetylmuramoyl-pentapeptide-transferase (mraY) is an enzyme responsible for the formation of the first lipid intermediate in the synthesis of bacterial cell wall peptidoglycan. It catalyzes the formation of...; Region: GT_MraY; cd06852 663951005600 Mg++ binding site [ion binding]; other site 663951005601 putative catalytic motif [active] 663951005602 putative substrate binding site [chemical binding]; other site 663951005603 10 probable transmembrane helices predicted for SATW20_11760 by TMHMM2.0 at aa 2-24, 47-69, 76-98, 113-135,142-164, 174-196, 201-220, 225-244, 251-273 and 301-320 663951005604 HMMPfam hit to PF00953, Glycos_transf_4, score 4.8e-84 663951005605 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase; Provisional; Region: murD; PRK02472 663951005606 Formate/glycerate dehydrogenases, D-specific 2-hydroxy acid dehydrogenases and related dehydrogenases; Region: FDH_GDH_like; cl17240 663951005607 NAD binding site [chemical binding]; other site 663951005608 Mur ligase middle domain; Region: Mur_ligase_M; pfam08245 663951005609 Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875 663951005610 HMMPfam hit to PF08245, Mur_ligase_M, score 7.4e-66 663951005611 HMMPfam hit to PF02875, Mur_ligase_C, score 1.5e-17 663951005612 Cell division septal protein [Cell envelope biogenesis, outer membrane]; Region: FtsQ; COG1589 663951005613 POTRA domain, FtsQ-type; Region: POTRA_1; pfam08478 663951005614 Cell division protein FtsQ; Region: FtsQ; pfam03799 663951005615 1 probable transmembrane helix predicted for SATW20_11780 by TMHMM2.0 at aa 171-193 663951005616 HMMPfam hit to PF08478, POTRA_1, score 5.9e-22 663951005617 HMMPfam hit to PF03799, FtsQ, score 2.5e-38 663951005618 Cell division ATPase FtsA [Cell division and chromosome partitioning]; Region: ftsA; COG0849 663951005619 Cell division protein FtsA; Region: FtsA; smart00842 663951005620 Cell division protein FtsA; Region: FtsA; pfam14450 663951005621 HMMPfam hit to PF02491, FtsA, score 1.7e-34 663951005622 HMMPfam hit to PF02491, FtsA, score 5.2e-51 663951005623 cell division protein FtsZ; Validated; Region: PRK09330 663951005624 FtsZ is a GTPase that is similar to the eukaryotic tubulins and is essential for cell division in prokaryotes. FtsZ is capable of polymerizing in a GTP-driven process into structures similar to those formed by tubulin. FtsZ forms a ring-shaped septum at...; Region: FtsZ_type1; cd02201 663951005625 nucleotide binding site [chemical binding]; other site 663951005626 SulA interaction site; other site 663951005627 HMMPfam hit to PF00091, Tubulin, score 1e-99 663951005628 PS01134 FtsZ protein signature 1. 663951005629 PS01135 FtsZ protein signature 2. 663951005630 HMMPfam hit to PF03953, Tubulin_C, score 1.1e-32 663951005631 Multicopper polyphenol oxidase (laccase) [Secondary metabolites biosynthesis, transport and catabolism]; Region: yfiH; COG1496 663951005632 Multi-copper polyphenol oxidoreductase laccase; Region: Cu-oxidase_4; pfam02578 663951005633 HMMPfam hit to PF02578, DUF152, score 4.2e-28 663951005634 Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes, YBL036c-like proteins; Region: PLPDE_III_YBL036c_like; cd00635 663951005635 pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site 663951005636 catalytic residue [active] 663951005637 HMMPfam hit to PF01168, Ala_racemase_N, score 5.3e-08 663951005638 Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1799 663951005639 HMMPfam hit to PF04472, DUF552, score 4.1e-44 663951005640 YGGT family; Region: YGGT; pfam02325 663951005641 HMMPfam hit to PF02325, YGGT, score 6.2e-34 663951005642 2 probable transmembrane helices predicted for SATW20_11840 by TMHMM2.0 at aa 12-34 and 59-81 663951005643 CDS contains a frameshift after codon 213. Frameshift occurs at a poly A heptamer 663951005644 HMMPfam hit to PF01479, S4, score 8.2e-12 663951005645 Cell division initiation protein [Cell division and chromosome partitioning]; Region: DivIVA; COG3599 663951005646 DivIVA domain; Region: DivI1A_domain; TIGR03544 663951005647 HMMPfam hit to PF05103, DivIVA, score 1.5e-19 663951005648 isoleucyl-tRNA synthetase; Reviewed; Region: ileS; PRK05743 663951005649 catalytic core domain of isoleucyl-tRNA synthetases; Region: IleRS_core; cd00818 663951005650 HIGH motif; other site 663951005651 Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603 663951005652 catalytic core domain of isoleucyl-tRNA synthetases; Region: IleRS_core; cd00818 663951005653 active site 663951005654 KMSKS motif; other site 663951005655 Anticodon-binding domain of bacterial and eukaryotic mitochondrial isoleucyl tRNA synthetases; Region: Anticodon_Ia_Ile_BEm; cd07960 663951005656 tRNA binding surface [nucleotide binding]; other site 663951005657 anticodon binding site; other site 663951005658 Zinc finger found in FPG and IleRS; Region: zf-FPG_IleRS; pfam06827 663951005659 HMMPfam hit to PF00133, tRNA-synt_1, score 0 663951005660 PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 663951005661 HMMPfam hit to PF08264, Anticodon_1, score 2.1e-59 663951005662 HMMPfam hit to PF06827, zf-FPG_IleRS, score 7.3e-15 663951005663 Predicted ring-cleavage extradiol dioxygenase [General function prediction only]; Region: COG2514 663951005664 This domain superfamily is found in a variety of structurally related metalloproteins, including the type I extradiol dioxygenases, glyoxalase I and a group of antibiotic resistance proteins; Region: Glo_EDI_BRP_like; cl14632 663951005665 active site 663951005666 HMMPfam hit to PF00903, Glyoxalase, score 2.3e-05 663951005667 Probable gene remnant 663951005668 lipoprotein signal peptidase; Reviewed; Region: lspA; PRK00376 663951005669 lipoprotein signal peptidase; Provisional; Region: PRK14787 663951005670 4 probable transmembrane helices predicted for SATW20_11900 by TMHMM2.0 at aa 7-29, 64-83, 90-109 and 129-151 663951005671 HMMPfam hit to PF01252, Peptidase_A8, score 1.7e-81 663951005672 PS00855 Signal peptidases II signature. 663951005673 Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564 663951005674 S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site; Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165 663951005675 RNA binding surface [nucleotide binding]; other site 663951005676 Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869 663951005677 active site 663951005678 HMMPfam hit to PF01479, S4, score 5.2e-10 663951005679 HMMPfam hit to PF00849, PseudoU_synth_2, score 1.4e-77 663951005680 PS01129 Rlu family of pseudouridine synthase signature. 663951005681 Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase [Nucleotide transport and metabolism]; Region: PyrR; COG2065 663951005682 bifunctional pyrimidine regulatory protein PyrR uracil phosphoribosyltransferase; Provisional; Region: PRK05205 663951005683 HMMPfam hit to PF00156, Pribosyltran, score 9.4e-14 663951005684 uracil transporter; Provisional; Region: PRK10720 663951005685 HMMPfam hit to PF00860, Xan_ur_permease, score 2e-132 663951005686 11 probable transmembrane helices predicted for SATW20_11930 by TMHMM2.0 at aa 47-69, 76-95, 100-122,129-151, 166-183, 190-212, 240-262, 317-339, 349-371,383-401 and 405-427 663951005687 PS01116 Xanthine/uracil permeases family signature. 663951005688 aspartate carbamoyltransferase catalytic subunit; Provisional; Region: pyrB; PRK00856 663951005689 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729 663951005690 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185 663951005691 HMMPfam hit to PF02729, OTCace_N, score 2.3e-54 663951005692 PS00097 Aspartate and ornithine carbamoyltransferases signature. 663951005693 HMMPfam hit to PF00185, OTCace, score 1.2e-25 663951005694 PS00639 Eukaryotic thiol (cysteine) proteases histidine active site. 663951005695 dihydroorotase; Validated; Region: pyrC; PRK09357 663951005696 Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281 663951005697 Dihydroorotase (DHOase), subgroup IIa; DHOases catalyze the reversible interconversion of carbamoyl aspartate to dihydroorotate, a key reaction in pyrimidine biosynthesis. This subgroup also contains proteins that lack the active site, like unc-33, a C; Region: DHOase_IIa; cd01317 663951005698 active site 663951005699 HMMPfam hit to PF01979, Amidohydro_1, score 2.8e-54 663951005700 PS00482 Dihydroorotase signature 1. 663951005701 PS00483 Dihydroorotase signature 2. 663951005702 carbamoyl phosphate synthase small subunit; Reviewed; Region: PRK12564 663951005703 Carbamoyl-phosphate synthase small chain, CPSase domain; Region: CPSase_sm_chain; pfam00988 663951005704 Small chain of the glutamine-dependent form of carbamoyl phosphate synthase, CPSase II; Region: GATase1_CPSase; cd01744 663951005705 catalytic site [active] 663951005706 subunit interface [polypeptide binding]; other site 663951005707 HMMPfam hit to PF00988, CPSase_sm_chain, score 2.7e-73 663951005708 HMMPfam hit to PF00117, GATase, score 1.1e-68 663951005709 PS00442 Glutamine amidotransferases class-I active site. 663951005710 carbamoyl phosphate synthase large subunit; Reviewed; Region: carB; PRK05294 663951005711 Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289 663951005712 Carbamoyl-phosphate synthase L chain, ATP binding domain; Region: CPSase_L_D2; pfam02786 663951005713 Carbamoyl-phosphate synthetase large chain, oligomerisation domain; Region: CPSase_L_D3; pfam02787 663951005714 Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289 663951005715 ATP-grasp domain; Region: ATP-grasp_4; cl17255 663951005716 Methylglyoxal synthase-like domain from type II glutamine-dependent carbamoyl phosphate synthetase (CSP). CSP, a CarA and CarB heterodimer, catalyzes the production of carbamoyl phosphate which is subsequently employed in the metabolic pathways...; Region: MGS_CPS_II; cd01424 663951005717 IMP binding site; other site 663951005718 dimer interface [polypeptide binding]; other site 663951005719 interdomain contacts; other site 663951005720 partial ornithine binding site; other site 663951005721 HMMPfam hit to PF00289, CPSase_L_chain, score 9.3e-54 663951005722 HMMPfam hit to PF02786, CPSase_L_D2, score 2.4e-140 663951005723 PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 663951005724 PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 663951005725 HMMPfam hit to PF02787, CPSase_L_D3, score 1.3e-65 663951005726 Predicted helix-turn-helix motif with score 1035.000, SD 2.71 at aa 490-511, sequence FSDKTIAHRFNMTEEEVYQLRM 663951005727 HMMPfam hit to PF00289, CPSase_L_chain, score 8.8e-31 663951005728 PS00639 Eukaryotic thiol (cysteine) proteases histidine active site. 663951005729 HMMPfam hit to PF02786, CPSase_L_D2, score 3.9e-37 663951005730 PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 663951005731 PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 663951005732 HMMPfam hit to PF02142, MGS, score 1.5e-30 663951005733 Orotidine 5'-phosphate decarboxylase (ODCase) is a dimeric enzyme that decarboxylates orotidine 5'-monophosphate (OMP) to form uridine 5'-phosphate (UMP), an essential step in the pyrimidine biosynthetic pathway. In mammals, UMP synthase...; Region: OMP_decarboxylase_like; cd04725 663951005734 active site 663951005735 dimer interface [polypeptide binding]; other site 663951005736 HMMPfam hit to PF00215, OMPdecase, score 3.7e-82 663951005737 PS00156 Orotidine 5'-phosphate decarboxylase active site. 663951005738 Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223 663951005739 active site 663951005740 HMMPfam hit to PF00156, Pribosyltran, score 4.6e-31 663951005741 PS00626 Regulator of chromosome condensation (RCC1) signature 2. 663951005742 PS00103 Purine/pyrimidine phosphoribosyl transferases signature. 663951005743 PS00012 Phosphopantetheine attachment site. 663951005744 Escherichia coli PhnB and similar proteins; the E. coli phnB gene is found next to an operon involved in the cleavage of carbon-phosphorus bonds in unactivated alkylphosphonates; Region: PhnB_like; cd06588 663951005745 dimer interface [polypeptide binding]; other site 663951005746 HMMPfam hit to PF06983, 3-dmu-9_3-mt, score 1.9e-71 663951005747 Predicted RNA-binding protein homologous to eukaryotic snRNP [Transcription]; Region: COG1293 663951005748 Domain of unknown function (DUF814); Region: DUF814; pfam05670 663951005749 HMMPfam hit to PF05670, DUF814, score 3.3e-41 663951005750 HMMPfam hit to PF05833, FbpA, score 1.6e-241 663951005751 Guanylate kinase [Nucleotide transport and metabolism]; Region: Gmk; COG0194 663951005752 Guanosine monophosphate kinase (GMPK, EC 2.7.4.8), also known as guanylate kinase (GKase), catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to guanosine monophosphate (GMP) to yield adenosine diphosphate (ADP) and guanosine...; Region: GMPK; cd00071 663951005753 catalytic site [active] 663951005754 G-X2-G-X-G-K; other site 663951005755 PS00856 Guanylate kinase signature. 663951005756 HMMPfam hit to PF00625, Guanylate_kin, score 8e-44 663951005757 DNA-directed RNA polymerase, subunit K/omega [Transcription]; Region: RpoZ; COG1758 663951005758 HMMPfam hit to PF01192, RNA_pol_Rpb6, score 1.4e-16 663951005759 bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase; Validated; Region: PRK05579 663951005760 Flavoprotein; Region: Flavoprotein; pfam02441 663951005761 DNA / pantothenate metabolism flavoprotein; Region: DFP; pfam04127 663951005762 HMMPfam hit to PF02441, Flavoprotein, score 6.5e-51 663951005763 HMMPfam hit to PF04127, DFP, score 1.7e-38 663951005764 Primosomal protein N' (replication factor Y) - superfamily II helicase [DNA replication, recombination, and repair]; Region: PriA; COG1198 663951005765 DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046 663951005766 ATP binding site [chemical binding]; other site 663951005767 putative Mg++ binding site [ion binding]; other site 663951005768 helicase superfamily c-terminal domain; Region: HELICc; smart00490 663951005769 nucleotide binding region [chemical binding]; other site 663951005770 ATP-binding site [chemical binding]; other site 663951005771 HMMPfam hit to PF00270, DEAD, score 6.1e-29 663951005772 PS00017 ATP/GTP-binding site motif A (P-loop). 663951005773 HMMPfam hit to PF00271, Helicase_C, score 7e-08 663951005774 1 probable transmembrane helix predicted for SATW20_12070 by TMHMM2.0 at aa 5-24 663951005775 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 663951005776 Predicted membrane protein [Function unknown]; Region: XynA; COG2314 663951005777 2 probable transmembrane helices predicted for SATW20_12080 by TMHMM2.0 at aa 6-25 and 32-54 663951005778 HMMPfam hit to PF05154, TM2, score 2e-22 663951005779 Polypeptide or peptide deformylase; a family of metalloenzymes that catalyzes the removal of the N-terminal formyl group in a growing polypeptide chain following translation initiation during protein synthesis in prokaryotes. These enzymes utilize Fe(II)...; Region: Pep_deformylase; cd00487 663951005780 active site 663951005781 catalytic residues [active] 663951005782 metal binding site [ion binding]; metal-binding site 663951005783 HMMPfam hit to PF01327, Pep_deformylase, score 1e-23 663951005784 methionyl-tRNA formyltransferase; Reviewed; Region: fmt; PRK00005 663951005785 Methionyl-tRNA formyltransferase, N-terminal hydrolase domain; Region: FMT_core_Met-tRNA-FMT_N; cd08646 663951005786 putative active site [active] 663951005787 substrate binding site [chemical binding]; other site 663951005788 putative cosubstrate binding site; other site 663951005789 catalytic site [active] 663951005790 C-terminal domain of Formyltransferase and other enzymes; Region: Met_tRNA_FMT_C; cd08704 663951005791 substrate binding site [chemical binding]; other site 663951005792 HMMPfam hit to PF00551, Formyl_trans_N, score 3.3e-48 663951005793 HMMPfam hit to PF02911, Formyl_trans_C, score 7.7e-28 663951005794 16S rRNA methyltransferase B; Provisional; Region: PRK14902 663951005795 NusB family; Region: NusB; pfam01029 663951005796 putative RNA binding site [nucleotide binding]; other site 663951005797 S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440 663951005798 S-adenosylmethionine binding site [chemical binding]; other site 663951005799 HMMPfam hit to PF01029, NusB, score 1.9e-33 663951005800 HMMPfam hit to PF01189, Nol1_Nop2_Fmu, score 1.6e-44 663951005801 PS00237 G-protein coupled receptors signature. 663951005802 ribosomal RNA large subunit methyltransferase N; Provisional; Region: PRK14455 663951005803 Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335 663951005804 FeS/SAM binding site; other site 663951005805 HMMPfam hit to PF04055, Radical_SAM, score 1.7e-19 663951005806 Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and deduced catalytic mechanism of PP2C phosphatases are similar to the PP1, PP2A, PP2B family of protein Ser/Thr phosphatases, with which PP2C shares no sequence...; Region: PP2Cc; cd00143 663951005807 Protein phosphatase 2C; Region: PP2C; pfam00481 663951005808 active site 663951005809 HMMPfam hit to PF00481, PP2C, score 3.5e-07 663951005810 Protein Kinases, catalytic domain; Region: PKc_like; cl09925 663951005811 Serine/Threonine protein kinases, catalytic domain; Region: S_TKc; smart00220 663951005812 active site 663951005813 ATP binding site [chemical binding]; other site 663951005814 substrate binding site [chemical binding]; other site 663951005815 activation loop (A-loop); other site 663951005816 Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2815 663951005817 PASTA domain of bacterial serine/threonine kinase pknB-like proteins. PknB is a member of a group of related transmembrane sensor kinases present in many gram positive bacteria, which has been shown to regulate cell shape in Mycobacterium tubercolosis; Region: PASTA_pknB; cd06577 663951005818 PASTA domain of bacterial serine/threonine kinase pknB-like proteins. PknB is a member of a group of related transmembrane sensor kinases present in many gram positive bacteria, which has been shown to regulate cell shape in Mycobacterium tubercolosis; Region: PASTA_pknB; cd06577 663951005819 PASTA domain of bacterial serine/threonine kinase pknB-like proteins. PknB is a member of a group of related transmembrane sensor kinases present in many gram positive bacteria, which has been shown to regulate cell shape in Mycobacterium tubercolosis; Region: PASTA_pknB; cd06577 663951005820 HMMPfam hit to PF00069, Pkinase, score 2.3e-62 663951005821 PS00107 Protein kinases ATP-binding region signature. 663951005822 PS00108 Serine/Threonine protein kinases active-site signature. 663951005823 1 probable transmembrane helix predicted for SATW20_12140 by TMHMM2.0 at aa 350-372 663951005824 HMMPfam hit to PF03793, PASTA, score 1.1e-09 663951005825 HMMPfam hit to PF03793, PASTA, score 1.5e-12 663951005826 HMMPfam hit to PF03793, PASTA, score 2.2e-15 663951005827 Predicted GTPases [General function prediction only]; Region: COG1162 663951005828 S1_YloQ_GTPase: YloQ GTase family (also known as YjeQ and CpgA), S1-like RNA-binding domain. Proteins in the YloQ GTase family bind the ribosome and have GTPase activity. The precise role of this family is unknown. The protein structure is composed of...; Region: S1_YloQ_GTPase; cd04466 663951005829 RNA binding site [nucleotide binding]; other site 663951005830 homodimer interface [polypeptide binding]; other site 663951005831 Ribosomal interacting GTPase YjeQ/EngC, a circularly permuted subfamily of the Ras GTPases; Region: YjeQ_EngC; cd01854 663951005832 GTPase/Zn-binding domain interface [polypeptide binding]; other site 663951005833 GTP/Mg2+ binding site [chemical binding]; other site 663951005834 G4 box; other site 663951005835 G5 box; other site 663951005836 G1 box; other site 663951005837 Switch I region; other site 663951005838 G2 box; other site 663951005839 G3 box; other site 663951005840 Switch II region; other site 663951005841 HMMPfam hit to PF03193, DUF258, score 1.1e-138 663951005842 PS00675 Sigma-54 interaction domain ATP-binding region A signature. 663951005843 PS00017 ATP/GTP-binding site motif A (P-loop). 663951005844 Pentose-5-phosphate-3-epimerase [Carbohydrate transport and metabolism]; Region: Rpe; COG0036 663951005845 Ribulose-5-phosphate 3-epimerase (RPE). This enzyme catalyses the interconversion of D-ribulose 5-phosphate (Ru5P) into D-xylulose 5-phosphate, as part of the Calvin cycle (reductive pentose phosphate pathway) in chloroplasts and in the oxidative pentose...; Region: RPE; cd00429 663951005846 substrate binding site [chemical binding]; other site 663951005847 hexamer interface [polypeptide binding]; other site 663951005848 metal binding site [ion binding]; metal-binding site 663951005849 HMMPfam hit to PF00834, Ribul_P_3_epim, score 2.2e-101 663951005850 PS01085 Ribulose-phosphate 3-epimerase family signature 1. 663951005851 PS01086 Ribulose-phosphate 3-epimerase family signature 2. 663951005852 Thiamine pyrophosphokinase [Coenzyme metabolism]; Region: THI80; COG1564 663951005853 Thiamine pyrophosphokinase; Region: TPK; cd07995 663951005854 active site 663951005855 dimerization interface [polypeptide binding]; other site 663951005856 thiamine binding site [chemical binding]; other site 663951005857 HMMPfam hit to PF04263, TPK_catalytic, score 1.4e-50 663951005858 HMMPfam hit to PF04265, TPK_B1_binding, score 8.7e-27 663951005859 50S ribosomal protein L28; Reviewed; Region: rpmB; PRK00359 663951005860 HMMPfam hit to PF00830, Ribosomal_L28, score 2.6e-26 663951005861 Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1302 663951005862 HMMPfam hit to PF03780, DUF322, score 1.3e-39 663951005863 Predicted kinase related to dihydroxyacetone kinase [General function prediction only]; Region: COG1461 663951005864 DAK2 domain; Region: Dak2; pfam02734 663951005865 HMMPfam hit to PF02734, Dak2, score 4.2e-80 663951005866 ATP-dependent DNA helicase RecG; Provisional; Region: PRK10917 663951005867 RecG_wedge_OBF: A subfamily of OB folds corresponding to the OB fold found in the N-terminal (wedge) domain of Escherichia coli RecG. RecG is a branched-DNA-specific helicase, which catalyzes the interconversion of a DNA replication fork to a...; Region: RecG_wedge_OBF; cd04488 663951005868 generic binding surface II; other site 663951005869 ssDNA binding site; other site 663951005870 DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046 663951005871 ATP binding site [chemical binding]; other site 663951005872 putative Mg++ binding site [ion binding]; other site 663951005873 Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079 663951005874 nucleotide binding region [chemical binding]; other site 663951005875 ATP-binding site [chemical binding]; other site 663951005876 HMMPfam hit to PF01336, tRNA_anti, score 0.39 663951005877 HMMPfam hit to PF00270, DEAD, score 2.7e-29 663951005878 PS00017 ATP/GTP-binding site motif A (P-loop). 663951005879 PS00435 Peroxidases proximal heme-ligand signature. 663951005880 HMMPfam hit to PF00271, Helicase_C, score 9.9e-23 663951005881 fatty acid biosynthesis transcriptional regulator; Provisional; Region: PRK04424 663951005882 The hotdog fold was initially identified in the E. coli FabA (beta-hydroxydecanoyl-acyl carrier protein (ACP)-dehydratase) structure and subsequently in 4HBT (4-hydroxybenzoyl-CoA thioesterase) from Pseudomonas. A number of other seemingly unrelated...; Region: hot_dog; cd03440 663951005883 active site 2 [active] 663951005884 active site 1 [active] 663951005885 putative phosphate acyltransferase; Provisional; Region: PRK05331 663951005886 HMMPfam hit to PF02504, FA_synthesis, score 1.4e-145 663951005887 PS00359 Ribosomal protein L11 signature. 663951005888 (acyl-carrier-protein) S-malonyltransferase [Lipid metabolism]; Region: FabD; COG0331 663951005889 malonyl CoA-acyl carrier protein transacylase; Region: fabD; TIGR00128 663951005890 HMMPfam hit to PF00698, Acyl_transf_1, score 5.2e-14 663951005891 PS00157 Ribulose bisphosphate carboxylase large chain active site. 663951005892 3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05557 663951005893 beta-Keto acyl carrier protein reductase (BKR), involved in Type II FAS, classical (c) SDRs; Region: BKR_SDR_c; cd05333 663951005894 NAD(P) binding site [chemical binding]; other site 663951005895 homotetramer interface [polypeptide binding]; other site 663951005896 homodimer interface [polypeptide binding]; other site 663951005897 active site 663951005898 HMMPfam hit to PF00106, adh_short, score 2.7e-48 663951005899 PS00061 Short-chain dehydrogenases/reductases family signature. 663951005900 acyl carrier protein; Provisional; Region: acpP; PRK00982 663951005901 HMMPfam hit to PF00550, PP-binding, score 1.9e-20 663951005902 PS00012 Phosphopantetheine attachment site. 663951005903 PS00038 Myc-type, 'helix-loop-helix' dimerization domain signature. 663951005904 ribonuclease III; Reviewed; Region: rnc; PRK00102 663951005905 RIBOc. Ribonuclease III C terminal domain. This group consists of eukaryotic, bacterial and archeal ribonuclease III (RNAse III) proteins. RNAse III is a double stranded RNA-specific endonuclease. Prokaryotic RNAse III is important in...; Region: RIBOc; cd00593 663951005906 dimerization interface [polypeptide binding]; other site 663951005907 active site 663951005908 metal binding site [ion binding]; metal-binding site 663951005909 Double-stranded RNA binding motif. Binding is not sequence specific but is highly specific for double stranded RNA. Found in a variety of proteins including dsRNA dependent protein kinase PKR, RNA helicases, Drosophila staufen protein, E. coli RNase III; Region: DSRM; cd00048 663951005910 dsRNA binding site [nucleotide binding]; other site 663951005911 HMMPfam hit to PF00636, Ribonuclease_3, score 4.3e-49 663951005912 PS00517 Ribonuclease III family signature. 663951005913 HMMPfam hit to PF00035, dsrm, score 1.3e-18 663951005914 Chromosome segregation ATPases [Cell division and chromosome partitioning]; Region: Smc; COG1196 663951005915 ATP-binding cassette domain of barmotin, a member of the SMC protein family; Region: ABC_SMC_barmotin; cd03278 663951005916 Walker A/P-loop; other site 663951005917 ATP binding site [chemical binding]; other site 663951005918 Q-loop/lid; other site 663951005919 DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes...; Region: TOP4c; cl00148 663951005920 SMC proteins Flexible Hinge Domain; Region: SMC_hinge; smart00968 663951005921 ATP-binding cassette domain of barmotin, a member of the SMC protein family; Region: ABC_SMC_barmotin; cd03278 663951005922 ABC transporter signature motif; other site 663951005923 Walker B; other site 663951005924 D-loop; other site 663951005925 H-loop/switch region; other site 663951005926 HMMPfam hit to PF02463, SMC_N, score 1.2e-121 663951005927 PS00017 ATP/GTP-binding site motif A (P-loop). 663951005928 HMMPfam hit to PF06470, SMC_hinge, score 2.4e-31 663951005929 signal recognition particle-docking protein FtsY; Provisional; Region: PRK10416 663951005930 SRP54-type protein, helical bundle domain; Region: SRP54_N; pfam02881 663951005931 The signal recognition particle (SRP) mediates the transport to or across the plasma membrane in bacteria and the endoplasmic reticulum in eukaryotes. SRP recognizes N-terminal sighnal sequences of newly synthesized polypeptides at the ribosome. The...; Region: SRP; cd03115 663951005932 P loop; other site 663951005933 GTP binding site [chemical binding]; other site 663951005934 PS00018 EF-hand calcium-binding domain. 663951005935 HMMPfam hit to PF02881, SRP54_N, score 5e-18 663951005936 HMMPfam hit to PF00448, SRP54, score 3.6e-127 663951005937 PS00017 ATP/GTP-binding site motif A (P-loop). 663951005938 PS00300 SRP54-type proteins GTP-binding domain signature. 663951005939 putative DNA-binding protein; Validated; Region: PRK00118 663951005940 Putative helix-turn-helix protein, YlxM / p13 like; Region: UPF0122; pfam04297 663951005941 HMMPfam hit to PF04297, UPF0122, score 3.7e-61 663951005942 Predicted helix-turn-helix motif with score 1776.000, SD 5.24 at aa 39-60, sequence YSLSEIADTFNVSRQAVYDNIR 663951005943 signal recognition particle protein; Provisional; Region: PRK10867 663951005944 SRP54-type protein, helical bundle domain; Region: SRP54_N; smart00963 663951005945 The signal recognition particle (SRP) mediates the transport to or across the plasma membrane in bacteria and the endoplasmic reticulum in eukaryotes. SRP recognizes N-terminal sighnal sequences of newly synthesized polypeptides at the ribosome. The...; Region: SRP; cd03115 663951005946 P loop; other site 663951005947 GTP binding site [chemical binding]; other site 663951005948 Signal peptide binding domain; Region: SRP_SPB; pfam02978 663951005949 HMMPfam hit to PF02881, SRP54_N, score 9.2e-33 663951005950 HMMPfam hit to PF00448, SRP54, score 1.7e-117 663951005951 PS00017 ATP/GTP-binding site motif A (P-loop). 663951005952 PS00300 SRP54-type proteins GTP-binding domain signature. 663951005953 HMMPfam hit to PF02978, SRP_SPB, score 2.4e-51 663951005954 Ribosomal protein S16 [Translation, ribosomal structure and biogenesis]; Region: RpsP; COG0228 663951005955 HMMPfam hit to PF00886, Ribosomal_S16, score 9.4e-32 663951005956 16S rRNA-processing protein RimM; Provisional; Region: rimM; PRK00122 663951005957 RimM N-terminal domain; Region: RimM; pfam01782 663951005958 PRC-barrel domain; Region: PRC; pfam05239 663951005959 HMMPfam hit to PF01782, RimM, score 1.3e-34 663951005960 HMMPfam hit to PF05239, PRC, score 1.5e-22 663951005961 tRNA (guanine-N(1)-)-methyltransferase; Reviewed; Region: trmD; PRK00026 663951005962 HMMPfam hit to PF01746, tRNA_m1G_MT, score 1.7e-80 663951005963 50S ribosomal protein L19; Provisional; Region: rplS; PRK05338 663951005964 HMMPfam hit to PF01245, Ribosomal_L19, score 9.2e-75 663951005965 PS01015 Ribosomal protein L19 signature. 663951005966 Predicted membrane protein [Function unknown]; Region: COG4485 663951005967 13 probable transmembrane helices predicted for SATW20_12360 by TMHMM2.0 at aa 15-37, 87-109, 124-146,153-175, 197-228, 249-271, 291-313, 320-342, 357-375,382-401, 405-427, 432-449 and 843-865 663951005968 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 663951005969 GTPase YlqF; Reviewed; Region: rbgA; PRK09563 663951005970 Circularly permuted YlqF GTPase; Region: YlqF; cd01856 663951005971 GTP/Mg2+ binding site [chemical binding]; other site 663951005972 G4 box; other site 663951005973 G5 box; other site 663951005974 G1 box; other site 663951005975 Switch I region; other site 663951005976 G2 box; other site 663951005977 G3 box; other site 663951005978 Switch II region; other site 663951005979 HMMPfam hit to PF01926, MMR_HSR1, score 3e-23 663951005980 PS00017 ATP/GTP-binding site motif A (P-loop). 663951005981 bacterial Ribonuclease HII-like; Region: RNase_HII_bacteria_HII_like; cd07182 663951005982 RNA/DNA hybrid binding site [nucleotide binding]; other site 663951005983 active site 663951005984 HMMPfam hit to PF01351, RNase_HII, score 2.9e-61 663951005985 succinyl-CoA synthetase subunit beta; Provisional; Region: sucC; PRK00696 663951005986 ATP-grasp domain; Region: ATP-grasp_2; pfam08442 663951005987 CoA-ligase; Region: Ligase_CoA; pfam00549 663951005988 HMMPfam hit to PF08442, ATP-grasp_2, score 1.3e-135 663951005989 PS00017 ATP/GTP-binding site motif A (P-loop). 663951005990 HMMPfam hit to PF00549, Ligase_CoA, score 9.5e-70 663951005991 PS01217 ATP-citrate lyase / succinyl-CoA ligases family signature 3. 663951005992 succinyl-CoA synthetase subunit alpha; Validated; Region: PRK05678 663951005993 CoA binding domain; Region: CoA_binding; pfam02629 663951005994 CoA-ligase; Region: Ligase_CoA; pfam00549 663951005995 HMMPfam hit to PF02629, CoA_binding, score 1.7e-46 663951005996 HMMPfam hit to PF00549, Ligase_CoA, score 2.7e-52 663951005997 PS01216 ATP-citrate lyase / succinyl-CoA ligases family signature 1. 663951005998 PS00399 ATP-citrate lyase / succinyl-CoA ligases family active site. 663951005999 CDS contains a frameshift after codon 168. Frameshift occurs at a poly A octamer 663951006000 HMMPfam hit to PF04650, YSIRK_signal, score 4.6e-07 663951006001 1 probable transmembrane helix predicted for SATW20_12410 by TMHMM2.0 at aa 12-31 663951006002 HMMPfam hit to PF01476, LysM, score 3.7e-11 663951006003 HMMPfam hit to PF05257, CHAP, score 3.7e-39 663951006004 PS00626 Regulator of chromosome condensation (RCC1) signature 2. 663951006005 FemAB family; Region: FemAB; pfam02388 663951006006 Acetyltransferase (GNAT) domain; Region: Acetyltransf_6; pfam13480 663951006007 HMMPfam hit to PF02388, FemAB, score 7.4e-248 663951006008 DNA protecting protein DprA; Region: dprA; TIGR00732 663951006009 DNA recombination-mediator protein A; Region: DNA_processg_A; pfam02481 663951006010 HMMPfam hit to PF02481, SMF, score 3.6e-125 663951006011 DNA topoisomerase I; Validated; Region: PRK05582 663951006012 TOPRIM_TopoIA_TopoI: The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to Escherichia coli DNA topoisomerase I. Type IA DNA topoisomerases remove (relax) negative supercoils in the...; Region: TOPRIM_TopoIA_TopoI; cd03363 663951006013 active site 663951006014 interdomain interaction site; other site 663951006015 putative metal-binding site [ion binding]; other site 663951006016 nucleotide binding site [chemical binding]; other site 663951006017 DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cd00186 663951006018 domain I; other site 663951006019 DNA binding groove [nucleotide binding] 663951006020 phosphate binding site [ion binding]; other site 663951006021 domain II; other site 663951006022 domain III; other site 663951006023 nucleotide binding site [chemical binding]; other site 663951006024 catalytic site [active] 663951006025 domain IV; other site 663951006026 Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396 663951006027 Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396 663951006028 HMMPfam hit to PF01751, Toprim, score 6e-38 663951006029 HMMPfam hit to PF01131, Topoisom_bac, score 5.2e-181 663951006030 PS00396 Prokaryotic DNA topoisomerase I active site. 663951006031 HMMPfam hit to PF01396, zf-C4_Topoisom, score 1.4e-19 663951006032 HMMPfam hit to PF01396, zf-C4_Topoisom, score 5.3e-17 663951006033 HMMPfam hit to PF01396, zf-C4_Topoisom, score 0.033 663951006034 tRNA (uracil-5-)-methyltransferase Gid; Reviewed; Region: PRK05335 663951006035 Glucose inhibited division protein A; Region: GIDA; pfam01134 663951006036 HMMPfam hit to PF01134, GIDA, score 1.3e-191 663951006037 tyrosine recombinase XerC; Region: recomb_XerC; TIGR02224 663951006038 DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213 663951006039 active site 663951006040 DNA binding site [nucleotide binding] 663951006041 Int/Topo IB signature motif; other site 663951006042 HMMPfam hit to PF02899, Phage_integr_N, score 9.4e-17 663951006043 HMMPfam hit to PF00589, Phage_integrase, score 6e-48 663951006044 Protease HslV and the ATPase/chaperone HslU are part of an ATP-dependent proteolytic system that is the prokaryotic homolog of the proteasome. HslV is a dimer of hexamers (a dodecamer) that forms a central proteolytic chamber with active sites on the...; Region: protease_HslV; cd01913 663951006045 active site 663951006046 HslU subunit interaction site [polypeptide binding]; other site 663951006047 HMMPfam hit to PF00227, Proteasome, score 1.3e-40 663951006048 ATP-dependent protease ATP-binding subunit HslU; Provisional; Region: hslU; PRK05201 663951006049 The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009 663951006050 Walker A motif; other site 663951006051 ATP binding site [chemical binding]; other site 663951006052 AAA domain (Cdc48 subfamily); Region: AAA_2; pfam07724 663951006053 Walker B motif; other site 663951006054 arginine finger; other site 663951006055 C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086 663951006056 HMMPfam hit to PF07724, AAA_2, score 4e-39 663951006057 PS00017 ATP/GTP-binding site motif A (P-loop). 663951006058 transcriptional repressor CodY; Validated; Region: PRK04158 663951006059 CodY GAF-like domain; Region: CodY; pfam06018 663951006060 CodY helix-turn-helix domain; Region: HTH_CodY; pfam08222 663951006061 HMMPfam hit to PF06018, CodY, score 7.1e-108 663951006062 HMMPfam hit to PF08222, HTH_CodY, score 1.7e-37 663951006063 Predicted helix-turn-helix motif with score 1382.000, SD 3.89 at aa 201-222, sequence LIASKVADRVGITRSVIVNALR 663951006064 Ribosomal protein S2 (RPS2), involved in formation of the translation initiation complex, where it might contact the messenger RNA and several components of the ribosome. It has been shown that in Escherichia coli RPS2 is essential for the binding of...; Region: RPS2; cd01425 663951006065 rRNA interaction site [nucleotide binding]; other site 663951006066 S8 interaction site; other site 663951006067 putative laminin-1 binding site; other site 663951006068 PS00962 Ribosomal protein S2 signature 1. 663951006069 HMMPfam hit to PF00318, Ribosomal_S2, score 3.7e-107 663951006070 PS00963 Ribosomal protein S2 signature 2. 663951006071 elongation factor Ts; Provisional; Region: tsf; PRK09377 663951006072 UBA/TS-N domain; Region: UBA; pfam00627 663951006073 Elongation factor TS; Region: EF_TS; pfam00889 663951006074 Elongation factor TS; Region: EF_TS; pfam00889 663951006075 HMMPfam hit to PF00627, UBA, score 1.9e-15 663951006076 PS01126 Elongation factor Ts signature 1. 663951006077 HMMPfam hit to PF00889, EF_TS, score 1.6e-102 663951006078 PS01127 Elongation factor Ts signature 2. 663951006079 UMP kinase (UMPK)-Ec, the microbial/chloroplast uridine monophosphate kinase (uridylate kinase) enzyme that catalyzes UMP phosphorylation and plays a key role in pyrimidine nucleotide biosynthesis; regulation of this process is via feed-back control and...; Region: AAK_UMPK-PyrH-Ec; cd04254 663951006080 putative nucleotide binding site [chemical binding]; other site 663951006081 uridine monophosphate binding site [chemical binding]; other site 663951006082 homohexameric interface [polypeptide binding]; other site 663951006083 HMMPfam hit to PF00696, AA_kinase, score 2.7e-64 663951006084 PS00017 ATP/GTP-binding site motif A (P-loop). 663951006085 ribosome recycling factor; Reviewed; Region: frr; PRK00083 663951006086 Ribosome recycling factor (RRF). Ribosome recycling factor dissociates the posttermination complex, composed of the ribosome, deacylated tRNA, and mRNA, after termination of translation. Thus ribosomes are "recycled" and ready for another...; Region: RRF; cd00520 663951006087 hinge region; other site 663951006088 HMMPfam hit to PF01765, RRF, score 6.1e-105 663951006089 Undecaprenyl pyrophosphate synthase [Lipid metabolism]; Region: UppS; COG0020 663951006090 Cis (Z)-Isoprenyl Diphosphate Synthases (cis-IPPS); homodimers which catalyze the successive 1'-4 condensation of the isopentenyl diphosphate (IPP) molecule to trans,trans-farnesyl diphosphate (FPP) or to cis,trans-FPP to form long-chain polyprenyl...; Region: CIS_IPPS; cd00475 663951006091 catalytic residue [active] 663951006092 putative FPP diphosphate binding site; other site 663951006093 putative FPP binding hydrophobic cleft; other site 663951006094 dimer interface [polypeptide binding]; other site 663951006095 putative IPP diphosphate binding site; other site 663951006096 HMMPfam hit to PF01255, Prenyltransf, score 3.3e-100 663951006097 PS01066 Undecaprenyl pyrophosphate synthetase family signature. 663951006098 CDP-diglyceride synthetase [Lipid metabolism]; Region: CdsA; COG0575 663951006099 Cytidylyltransferase family; Region: CTP_transf_1; pfam01148 663951006100 HMMPfam hit to PF01148, CTP_transf_1, score 4.8e-99 663951006101 7 probable transmembrane helices predicted for SATW20_12550 by TMHMM2.0 at aa 7-29, 44-66, 73-95, 100-122,129-151, 171-190 and 197-216 663951006102 PS01315 Phosphatidate cytidylyltransferase signature. 663951006103 RIP metalloprotease RseP; Region: TIGR00054 663951006104 RseP-like Site-2 proteases (S2P), zinc metalloproteases (MEROPS family M50A), cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. In Escherichia coli, the S2P homolog...; Region: S2P-M50_PDZ_RseP-like; cd06163 663951006105 active site 663951006106 Site-2 protease (S2P) class of zinc metalloproteases (MEROPS family M50) cleaves transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. Members of this family use proteolytic...; Region: S2P-M50; cl10020 663951006107 PDZ domain of bacterial and plant zinc metalloprotases, presumably membrane-associated or integral membrane proteases, which may be involved in signalling and regulatory mechanisms. May be responsible for substrate recognition and/or binding, as most PDZ...; Region: PDZ_metalloprotease; cd00989 663951006108 protein binding site [polypeptide binding]; other site 663951006109 RseP-like Site-2 proteases (S2P), zinc metalloproteases (MEROPS family M50A), cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. In Escherichia coli, the S2P homolog...; Region: S2P-M50_PDZ_RseP-like; cd06163 663951006110 putative substrate binding region [chemical binding]; other site 663951006111 5 probable transmembrane helices predicted for SATW20_12560 by TMHMM2.0 at aa 4-21, 172-194, 307-329,350-372 and 401-420 663951006112 HMMPfam hit to PF02163, Peptidase_M50, score 6.2e-91 663951006113 PS00142 Neutral zinc metallopeptidases, zinc-binding region signature. 663951006114 prolyl-tRNA synthetase; Provisional; Region: PRK09194 663951006115 Prolyl-tRNA synthetase (ProRS) class II core catalytic domain. ProRS is a homodimer. It is responsible for the attachment of proline to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ProRS_core_prok; cd00779 663951006116 dimer interface [polypeptide binding]; other site 663951006117 motif 1; other site 663951006118 active site 663951006119 motif 2; other site 663951006120 INS is an amino acid-editing domain inserted (INS) into the bacterial class II prolyl-tRNA synthetase (ProRS) however, this CD is not exclusively bacterial. It is also found at the N-terminus of the eukaryotic/archaea-like ProRS's of yeasts and...; Region: ProRS-INS; cd04334 663951006121 putative deacylase active site [active] 663951006122 Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA. PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268 663951006123 active site 663951006124 motif 3; other site 663951006125 ProRS Prolyl-anticodon binding domain, short version found predominantly in bacteria. ProRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding; Region: ProRS_anticodon_short; cd00861 663951006126 anticodon binding site; other site 663951006127 HMMPfam hit to PF00587, tRNA-synt_2b, score 3.9e-59 663951006128 PS00179 Aminoacyl-transfer RNA synthetases class-II signature 1. 663951006129 HMMPfam hit to PF04073, YbaK, score 7.7e-15 663951006130 HMMPfam hit to PF03129, HGTP_anticodon, score 4.6e-23 663951006131 DNA polymerase III PolC; Validated; Region: polC; PRK00448 663951006132 DNA polymerase III polC-type N-terminus; Region: DNA_pol3_alph_N; pfam11490 663951006133 polC_OBF: A subfamily of OB folds corresponding to the N-terminal OB-fold nucleic acid binding domain of Bacillus subtilis type C replicative DNA polymerase III alpha subunit (polC). Replication in B. subtilis and Staphylococcus aureus requires two...; Region: polC_OBF; cd04484 663951006134 generic binding surface II; other site 663951006135 generic binding surface I; other site 663951006136 Polymerase and Histidinol Phosphatase domain; Region: PHP; cl17102 663951006137 active site 663951006138 DEDDh 3'-5' exonuclease domain family; Region: DEDDh; cd06127 663951006139 active site 663951006140 catalytic site [active] 663951006141 substrate binding site [chemical binding]; other site 663951006142 Polymerase and Histidinol Phosphatase domain of alpha-subunit of bacterial polymerase III at PolC gene; Region: PHP_PolIIIA_POLC; cd07435 663951006143 HMMPfam hit to PF01336, tRNA_anti, score 2.3e-07 663951006144 HMMPfam hit to PF02811, PHP, score 6.1e-52 663951006145 HMMPfam hit to PF00929, Exonuc_X-T, score 2.3e-58 663951006146 HMMPfam hit to PF07733, DNA_pol3_alpha, score 4.9e-209 663951006147 ribosome maturation protein RimP; Reviewed; Region: PRK00092 663951006148 Sm and related proteins; Region: Sm_like; cl00259 663951006149 Bacillus subtilis YxlS-like, C-terminal domain; Region: YlxS_C; cd01734 663951006150 putative oligomer interface [polypeptide binding]; other site 663951006151 putative RNA binding site [nucleotide binding]; other site 663951006152 HMMPfam hit to PF02576, DUF150, score 1.2e-70 663951006153 transcription elongation factor NusA; Provisional; Region: nusA; PRK12327 663951006154 NusA N-terminal domain; Region: NusA_N; pfam08529 663951006155 S1_NusA: N-utilizing substance A protein (NusA), S1-like RNA-binding domain. S1-like RNA-binding domains are found in a wide variety of RNA-associated proteins. NusA is a transcription elongation factor containing an N-terminal catalytic domain and three...; Region: S1_NusA; cd04455 663951006156 RNA binding site [nucleotide binding]; other site 663951006157 homodimer interface [polypeptide binding]; other site 663951006158 NusA-like KH domain; Region: KH_5; pfam13184 663951006159 NusA_K homology RNA-binding domain (KH). NusA is an essential multifunctional transcription elongation factor that is universally conserved among prokaryotes and archaea. NusA anti-termination function plays an important role in the expression of...; Region: NusA_KH; cd02134 663951006160 G-X-X-G motif; other site 663951006161 HMMPfam hit to PF08529, NusA_N, score 1.7e-65 663951006162 HMMPfam hit to PF00575, S1, score 7.6e-06 663951006163 HMMPfam hit to PF00013, KH_1, score 0.037 663951006164 Ylxr homologs; group of conserved hypothetical bacterial proteins of unknown function; structure revealed putative RNA binding cleft; proteins are encoded by an operon that includes other proteins involved in transcription and/or translation; Region: YlxR; cd00279 663951006165 putative RNA binding cleft [nucleotide binding]; other site 663951006166 HMMPfam hit to PF04296, DUF448, score 3.6e-40 663951006167 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family; Region: Ribosomal_L7Ae; cl00600 663951006168 HMMPfam hit to PF01248, Ribosomal_L7Ae, score 5.6e-19 663951006169 Translation initiation factor IF-2, N-terminal region; Region: IF2_N; pfam04760 663951006170 translation initiation factor IF-2; Region: IF-2; TIGR00487 663951006171 Translation initiation factor IF-2, N-terminal region; Region: IF2_N; pfam04760 663951006172 Initiation Factor 2 (IF2)/ eukaryotic Initiation Factor 5B (eIF5B) family; Region: IF2_eIF5B; cd01887 663951006173 G1 box; other site 663951006174 putative GEF interaction site [polypeptide binding]; other site 663951006175 GTP/Mg2+ binding site [chemical binding]; other site 663951006176 Switch I region; other site 663951006177 G2 box; other site 663951006178 G3 box; other site 663951006179 Switch II region; other site 663951006180 G4 box; other site 663951006181 G5 box; other site 663951006182 This family represents the domain II of bacterial Initiation Factor 2 (IF2) and its eukaryotic mitochondrial homologue mtIF2. IF2, the largest initiation factor is an essential GTP binding protein. In E. coli three natural forms of IF2 exist in the cell; Region: IF2_mtIF2_II; cd03702 663951006183 Translation-initiation factor 2; Region: IF-2; pfam11987 663951006184 mtIF2_IVc: this family represents the C2 subdomain of domain IV of mitochondrial translation initiation factor 2 (mtIF2) which adopts a beta-barrel fold displaying a high degree of structural similarity with domain II of the translation elongation factor...; Region: mtIF2_IVc; cd03692 663951006185 HMMPfam hit to PF04760, IF2_N, score 8.2e-19 663951006186 HMMPfam hit to PF04760, IF2_N, score 3.2e-23 663951006187 HMMPfam hit to PF00009, GTP_EFTU, score 5.2e-52 663951006188 PS00017 ATP/GTP-binding site motif A (P-loop). 663951006189 HMMPfam hit to PF03144, GTP_EFTU_D2, score 6.6e-12 663951006190 HMMPfam hit to PF03144, GTP_EFTU_D2, score 1.4e-08 663951006191 PS01176 Initiation factor 2 signature. 663951006192 ribosome-binding factor A; Validated; Region: rbfA; PRK00521 663951006193 HMMPfam hit to PF02033, RBFA, score 4.8e-47 663951006194 tRNA pseudouridine synthase B; Provisional; Region: PRK14123 663951006195 Pseudouridine synthase, Escherichia coli TruB like; Region: PseudoU_synth_EcTruB; cd02573 663951006196 RNA binding site [nucleotide binding]; other site 663951006197 active site 663951006198 HMMPfam hit to PF01509, TruB_N, score 3.4e-68 663951006199 FAD synthase [Coenzyme metabolism]; Region: RibF; COG0196 663951006200 FAD synthetase, N-terminal domain of the bifunctional enzyme; Region: FAD_synthetase_N; cd02064 663951006201 active site 663951006202 Riboflavin kinase; Region: Flavokinase; smart00904 663951006203 HMMPfam hit to PF06574, FAD_syn, score 6.2e-71 663951006204 HMMPfam hit to PF01687, Flavokinase, score 2.8e-55 663951006205 Ribosomal protein S15 (prokaryotic)_S13 (eukaryotic) binds the central domain of 16S rRNA and is required for assembly of the small ribosomal subunit and for intersubunit association, thus representing a key element in the assembly of the whole ribosome; Region: Ribosomal_S15p_S13e; cd00353 663951006206 16S/18S rRNA binding site [nucleotide binding]; other site 663951006207 S13e-L30e interaction site [polypeptide binding]; other site 663951006208 25S rRNA binding site [nucleotide binding]; other site 663951006209 HMMPfam hit to PF00312, Ribosomal_S15, score 2.4e-36 663951006210 PS00362 Ribosomal protein S15 signature. 663951006211 polynucleotide phosphorylase/polyadenylase; Provisional; Region: PRK11824 663951006212 Polyribonucleotide nucleotidyltransferase, repeat 1; Region: RNase_PH_PNPase_1; cd11363 663951006213 RNase E interface [polypeptide binding]; other site 663951006214 trimer interface [polypeptide binding]; other site 663951006215 Polyribonucleotide nucleotidyltransferase, RNA binding domain; Region: PNPase; pfam03726 663951006216 Polyribonucleotide nucleotidyltransferase, repeat 2; Region: RNase_PH_PNPase_2; cd11364 663951006217 RNase E interface [polypeptide binding]; other site 663951006218 trimer interface [polypeptide binding]; other site 663951006219 active site 663951006220 Polynucleotide phosphorylase (PNPase) K homology RNA-binding domain (KH). PNPase is a polyribonucleotide nucleotidyl transferase that degrades mRNA in prokaryotes and plant chloroplasts. The C-terminal region of PNPase contains domains homologous to...; Region: PNPase_KH; cd02393 663951006221 putative nucleic acid binding region [nucleotide binding]; other site 663951006222 G-X-X-G motif; other site 663951006223 S1_PNPase: Polynucleotide phosphorylase (PNPase), ), S1-like RNA-binding domain. PNPase is a polyribonucleotide nucleotidyl transferase that degrades mRNA. It is a trimeric multidomain protein. The C-terminus contains the S1 domain which binds ssRNA; Region: S1_PNPase; cd04472 663951006224 RNA binding site [nucleotide binding]; other site 663951006225 domain interface; other site 663951006226 HMMPfam hit to PF01138, RNase_PH, score 2.5e-42 663951006227 HMMPfam hit to PF03725, RNase_PH_C, score 1.8e-15 663951006228 HMMPfam hit to PF03726, PNPase, score 8.3e-14 663951006229 HMMPfam hit to PF01138, RNase_PH, score 2.1e-48 663951006230 HMMPfam hit to PF03725, RNase_PH_C, score 1.7e-24 663951006231 HMMPfam hit to PF00013, KH_1, score 4.1e-14 663951006232 HMMPfam hit to PF00575, S1, score 5.1e-24 663951006233 mRNA degradation ribonucleases J1/J2 (metallo-beta-lactamase superfamily) [Translation, ribosomal structure and biogenesis; Replication, recombination and repair]; Region: COG0595 663951006234 Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849 663951006235 RNA-metabolising metallo-beta-lactamase; Region: RMMBL; pfam07521 663951006236 HMMPfam hit to PF00753, Lactamase_B, score 2e-21 663951006237 HMMPfam hit to PF07521, RMMBL, score 7.4e-12 663951006238 Domain of unknown function (DUF4117); Region: DUF4117; pfam13491 663951006239 FtsK/SpoIIIE family; Region: FtsK_SpoIIIE; pfam01580 663951006240 ATPases associated with a variety of cellular activities; Region: AAA; smart00382 663951006241 Type 1 periplasmic binding fold superfamily; Region: Periplasmic_Binding_Protein_Type_1; cl10011 663951006242 Ftsk gamma domain; Region: Ftsk_gamma; pfam09397 663951006243 5 probable transmembrane helices predicted for SATW20_12700 by TMHMM2.0 at aa 31-53, 63-85, 97-119,134-151 and 158-180 663951006244 HMMPfam hit to PF01580, FtsK_SpoIIIE, score 5.5e-81 663951006245 PS00017 ATP/GTP-binding site motif A (P-loop). 663951006246 Transcriptional regulators [Transcription]; Region: PhnF; COG2188 663951006247 Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cl17414 663951006248 DNA-binding site [nucleotide binding]; DNA binding site 663951006249 UTRA domain; Region: UTRA; pfam07702 663951006250 HMMPfam hit to PF00392, GntR, score 0.0027 663951006251 HMMPfam hit to PF07702, UTRA, score 2e-31 663951006252 Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612 663951006253 Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193 663951006254 HMMPfam hit to PF05193, Peptidase_M16_C, score 1.9e-38 663951006255 Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612 663951006256 Insulinase (Peptidase family M16); Region: Peptidase_M16; pfam00675 663951006257 Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193 663951006258 HMMPfam hit to PF00675, Peptidase_M16, score 1.8e-07 663951006259 HMMPfam hit to PF05193, Peptidase_M16_C, score 1.2e-30 663951006260 3-ketoacyl-(acyl-carrier-protein) reductase; Provisional; Region: fabG; PRK05565 663951006261 classical (c) SDRs; Region: SDR_c; cd05233 663951006262 NAD(P) binding site [chemical binding]; other site 663951006263 active site 663951006264 HMMPfam hit to PF01370, Epimerase, score 1.6e-06 663951006265 ACT domains are commonly involved in specifically binding an amino acid or other small ligand leading to regulation of the enzyme; Region: ACT; cl09141 663951006266 Protein of unknown function (DUF3388); Region: DUF3388; pfam11868 663951006267 HMMPfam hit to PF01842, ACT, score 0.00014 663951006268 1 probable transmembrane helix predicted for SATW20_12750 by TMHMM2.0 at aa 21-43 663951006269 PS00017 ATP/GTP-binding site motif A (P-loop). 663951006270 Predicted transcriptional regulator contains Xre-like HTH domain [Function unknown]; Region: COG1426 663951006271 Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093 663951006272 non-specific DNA binding site [nucleotide binding]; other site 663951006273 salt bridge; other site 663951006274 sequence-specific DNA binding site [nucleotide binding]; other site 663951006275 Predicted helix-turn-helix motif with score 1176.000, SD 3.19 at aa 17-38, sequence MTLTELEQRTGIKREMLVHIEN 663951006276 1 probable transmembrane helix predicted for SATW20_12760 by TMHMM2.0 at aa 107-129 663951006277 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; Region: pgsA; TIGR00560 663951006278 CDP-diacylglycerol--serine O-phosphatidyltransferase; Region: pssA; TIGR00473 663951006279 4 probable transmembrane helices predicted for SATW20_12770 by TMHMM2.0 at aa 7-29, 44-63, 84-106 and 157-179 663951006280 HMMPfam hit to PF01066, CDP-OH_P_transf, score 1e-38 663951006281 PS00379 CDP-alcohol phosphatidyltransferases signature. 663951006282 Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA [General function prediction only]; Region: CinA; COG1058 663951006283 Competence-damaged protein. CinA is the first gene in the competence- inducible (cin) operon and is thought to be specifically required at some stage in the process of transformation. This domain is closely related to a domain, found in a variety of...; Region: cinA; cd00885 663951006284 putative MPT binding site; other site 663951006285 HMMPfam hit to PF00994, MoCF_biosynth, score 2.4e-51 663951006286 recombinase A; Provisional; Region: recA; PRK09354 663951006287 RecA is a bacterial enzyme which has roles in homologous recombination, DNA repair, and the induction of the SOS response. RecA couples ATP hydrolysis to DNA strand exchange; Region: recA; cd00983 663951006288 hexamer interface [polypeptide binding]; other site 663951006289 Walker A motif; other site 663951006290 ATP binding site [chemical binding]; other site 663951006291 Walker B motif; other site 663951006292 HMMPfam hit to PF00154, RecA, score 1.1e-252 663951006293 PS00017 ATP/GTP-binding site motif A (P-loop). 663951006294 PS00321 recA signature. 663951006295 phosphodiesterase; Provisional; Region: PRK12704 663951006296 Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077 663951006297 Zn2+ binding site [ion binding]; other site 663951006298 Mg2+ binding site [ion binding]; other site 663951006299 1 probable transmembrane helix predicted for SATW20_12800 by TMHMM2.0 at aa 2-24 663951006300 HMMPfam hit to PF00013, KH_1, score 3.6e-08 663951006301 HMMPfam hit to PF01966, HD, score 3.1e-26 663951006302 Deinococcus radiodurans DR1281 and related proteins, metallophosphatase domain; Region: MPP_DR1281; cd07382 663951006303 Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149 663951006304 putative active site [active] 663951006305 metal binding site [ion binding]; metal-binding site 663951006306 homodimer binding site [polypeptide binding]; other site 663951006307 HMMPfam hit to PF00149, Metallophos, score 3.4e-08 663951006308 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit [Energy production and conversion]; Region: PorG; COG1014 663951006309 2-oxoacid:acceptor oxidoreductase, alpha subunit; Region: OAFO_sf; TIGR03710 663951006310 Pyrimidine (PYR) binding domain of pyruvate ferredoxin oxidoreductase (PFOR), indolepyruvate ferredoxin oxidoreductase alpha subunit (IOR-alpha), and related proteins; Region: TPP_PYR_PFOR_IOR-alpha_like; cd07034 663951006311 dimer interface [polypeptide binding]; other site 663951006312 PYR/PP interface [polypeptide binding]; other site 663951006313 TPP binding site [chemical binding]; other site 663951006314 substrate binding site [chemical binding]; other site 663951006315 HMMPfam hit to PF01558, POR, score 4.4e-08 663951006316 HMMPfam hit to PF01855, POR_N, score 1.7e-83 663951006317 2-oxoglutarate ferredoxin oxidoreductase subunit beta; Reviewed; Region: PRK11867 663951006318 Thiamine pyrophosphate (TPP family), 2-oxoglutarate ferredoxin oxidoreductase (OGFOR) subfamily, TPP-binding module; OGFOR catalyzes the oxidative decarboxylation of 2-oxo-acids, with ferredoxin acting as an electron acceptor. In the TCA cycle, OGFOR...; Region: TPP_OGFOR; cd03375 663951006319 TPP-binding site [chemical binding]; other site 663951006320 Pyruvate ferredoxin oxidoreductase beta subunit C terminal; Region: PFO_beta_C; pfam12367 663951006321 HMMPfam hit to PF02775, TPP_enzyme_C, score 4e-54 663951006322 Uncharacterized conserved protein [Function unknown]; Region: COG0011 663951006323 (dimethylallyl)adenosine tRNA methylthiotransferase; Provisional; Region: PRK14327 663951006324 Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919 663951006325 Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335 663951006326 FeS/SAM binding site; other site 663951006327 TRAM domain; Region: TRAM; pfam01938 663951006328 HMMPfam hit to PF00919, UPF0004, score 1.8e-49 663951006329 HMMPfam hit to PF04055, Radical_SAM, score 2e-38 663951006330 PS01278 Uncharacterized protein family UPF0004 signature. 663951006331 HMMPfam hit to PF01938, TRAM, score 5.6e-15 663951006332 Predicted membrane protein [Function unknown]; Region: COG4550 663951006333 Predicted membrane protein [Function unknown]; Region: COG4732 663951006334 5 probable transmembrane helices predicted for SATW20_12880 by TMHMM2.0 at aa 6-28, 37-59, 69-91, 98-120 and 130-152 663951006335 DNA mismatch repair protein MutS; Provisional; Region: PRK05399 663951006336 MutS domain I; Region: MutS_I; pfam01624 663951006337 MutS domain II; Region: MutS_II; pfam05188 663951006338 MutS domain III; Region: MutS_III; pfam05192 663951006339 ATP-binding cassette domain of MutS1 homolog; Region: ABC_MutS1; cd03284 663951006340 Walker A/P-loop; other site 663951006341 ATP binding site [chemical binding]; other site 663951006342 Q-loop/lid; other site 663951006343 ABC transporter signature motif; other site 663951006344 Walker B; other site 663951006345 D-loop; other site 663951006346 H-loop/switch region; other site 663951006347 HMMPfam hit to PF01624, MutS_I, score 4.3e-51 663951006348 HMMPfam hit to PF05188, MutS_II, score 3.6e-30 663951006349 HMMPfam hit to PF05192, MutS_III, score 1.5e-86 663951006350 HMMPfam hit to PF05190, MutS_IV, score 2.3e-41 663951006351 HMMPfam hit to PF00488, MutS_V, score 4.4e-141 663951006352 PS00017 ATP/GTP-binding site motif A (P-loop). 663951006353 PS00486 DNA mismatch repair proteins mutS family signature. 663951006354 DNA mismatch repair protein; Reviewed; Region: mutL; PRK00095 663951006355 Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075 663951006356 ATP binding site [chemical binding]; other site 663951006357 Mg2+ binding site [ion binding]; other site 663951006358 G-X-G motif; other site 663951006359 MutL_Trans: transducer domain, having a ribosomal S5 domain 2-like fold, conserved in the C-terminal domain of DNA mismatch repair (MutL/MLH1/PMS2) family. This transducer domain is homologous to the second domain of the DNA gyrase B subunit, which is...; Region: MutL_Trans; cd00782 663951006360 ATP binding site [chemical binding]; other site 663951006361 MutL C terminal dimerisation domain; Region: MutL_C; pfam08676 663951006362 HMMPfam hit to PF02518, HATPase_c, score 1.7e-12 663951006363 PS00058 DNA mismatch repair proteins mutL / hexB / PMS1 signature. 663951006364 PS00017 ATP/GTP-binding site motif A (P-loop). 663951006365 HMMPfam hit to PF01119, DNA_mis_repair, score 2.2e-43 663951006366 HMMPfam hit to PF08676, MutL_C, score 9.7e-63 663951006367 Glycerol-3-phosphate responsive antiterminator; Region: G3P_antiterm; pfam04309 663951006368 HMMPfam hit to PF04309, G3P_antiterm, score 4.6e-109 663951006369 Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family) [Carbohydrate transport and metabolism]; Region: GlpF; COG0580 663951006370 amphipathic channel; other site 663951006371 Asn-Pro-Ala signature motifs; other site 663951006372 HMMPfam hit to PF00230, MIP, score 6.5e-35 663951006373 7 probable transmembrane helices predicted for SATW20_12920 by TMHMM2.0 at aa 5-27, 39-61, 81-103,131-153, 163-185, 211-233 and 237-259 663951006374 PS00221 MIP family signature. 663951006375 glycerol kinase; Provisional; Region: glpK; PRK00047 663951006376 Escherichia coli glycerol kinase-like proteins; belongs to the FGGY family of carbohydrate kinases; Region: FGGY_EcGK_like; cd07786 663951006377 N- and C-terminal domain interface [polypeptide binding]; other site 663951006378 active site 663951006379 MgATP binding site [chemical binding]; other site 663951006380 catalytic site [active] 663951006381 metal binding site [ion binding]; metal-binding site 663951006382 glycerol binding site [chemical binding]; other site 663951006383 homotetramer interface [polypeptide binding]; other site 663951006384 homodimer interface [polypeptide binding]; other site 663951006385 FBP binding site [chemical binding]; other site 663951006386 protein IIAGlc interface [polypeptide binding]; other site 663951006387 HMMPfam hit to PF00370, FGGY_N, score 4.2e-120 663951006388 HMMPfam hit to PF02782, FGGY_C, score 2.6e-101 663951006389 PS00445 FGGY family of carbohydrate kinases signature 2. 663951006390 Glycerol-3-phosphate dehydrogenase [Energy production and conversion]; Region: GlpA; COG0578 663951006391 HMMPfam hit to PF01266, DAO, score 1.8e-73 663951006392 PS00977 FAD-dependent glycerol-3-phosphate dehydrogenase signature 1. 663951006393 PS00978 FAD-dependent glycerol-3-phosphate dehydrogenase signature 2. 663951006394 Lysophospholipase [Lipid metabolism]; Region: PldB; COG2267 663951006395 Putative lysophospholipase; Region: Hydrolase_4; pfam12146 663951006396 Cofactor of BRCA1 (COBRA1); Region: COBRA1; pfam06209 663951006397 HMMPfam hit to PF00561, Abhydrolase_1, score 2.8e-09 663951006398 tRNA delta(2)-isopentenylpyrophosphate transferase; Reviewed; Region: miaA; PRK00091 663951006399 tRNA delta(2)-isopentenylpyrophosphate transferase [Translation, ribosomal structure and biogenesis]; Region: MiaA; COG0324 663951006400 PS00017 ATP/GTP-binding site motif A (P-loop). 663951006401 HMMPfam hit to PF01715, IPPT, score 1.2e-100 663951006402 bacterial Hfq-like; Region: Hfq; cd01716 663951006403 hexamer interface [polypeptide binding]; other site 663951006404 Sm1 motif; other site 663951006405 RNA binding site [nucleotide binding]; other site 663951006406 Sm2 motif; other site 663951006407 HMMPfam hit to PF01423, LSM, score 2.6e-08 663951006408 Glutathione (GSH) peroxidase family; tetrameric selenoenzymes that catalyze the reduction of a variety of hydroperoxides including lipid peroxidases, using GSH as a specific electron donor substrate. GSH peroxidase contains one selenocysteine residue per...; Region: GSH_Peroxidase; cd00340 663951006409 catalytic residues [active] 663951006410 dimer interface [polypeptide binding]; other site 663951006411 HMMPfam hit to PF00255, GSHPx, score 5.6e-47 663951006412 PS00763 Glutathione peroxidases signature 2. 663951006413 GTP-binding protein HflX; Region: GTP_HflX; TIGR03156 663951006414 GTP-binding GTPase N-terminal; Region: GTP-bdg_N; pfam13167 663951006415 HflX GTPase family; Region: HflX; cd01878 663951006416 G1 box; other site 663951006417 GTP/Mg2+ binding site [chemical binding]; other site 663951006418 Switch I region; other site 663951006419 G2 box; other site 663951006420 G3 box; other site 663951006421 Switch II region; other site 663951006422 G4 box; other site 663951006423 G5 box; other site 663951006424 HMMPfam hit to PF04471, Mrr_cat, score 1.9e-21 663951006425 HMMPfam hit to PF01926, MMR_HSR1, score 4.6e-35 663951006426 PS00017 ATP/GTP-binding site motif A (P-loop). 663951006427 Cystathionine beta-lyase family protein involved in aluminum resistance [Inorganic ion transport and metabolism]; Region: COG4100 663951006428 Aluminium resistance protein; Region: Alum_res; pfam06838 663951006429 HMMPfam hit to PF06838, Alum_res, score 5.1e-298 663951006430 Helix-Turn-Helix DNA binding domain of GlnR-like transcription regulators; Region: HTH_GlnR-like; cd01105 663951006431 MerR HTH family regulatory protein; Region: MerR_1; pfam13411 663951006432 DNA binding residues [nucleotide binding] 663951006433 putative dimer interface [polypeptide binding]; other site 663951006434 Predicted helix-turn-helix motif with score 1281.000, SD 3.55 at aa 14-35, sequence FSMSVVSKLTDLTPRQIRYYET 663951006435 HMMPfam hit to PF00376, MerR, score 2.1e-09 663951006436 Glutamine synthetase [Amino acid transport and metabolism]; Region: GlnA; COG0174 663951006437 Glutamine synthetase, beta-Grasp domain; Region: Gln-synt_N; pfam03951 663951006438 Glutamine synthetase, catalytic domain; Region: Gln-synt_C; pfam00120 663951006439 HMMPfam hit to PF03951, Gln-synt_N, score 5.4e-20 663951006440 PS00180 Glutamine synthetase signature 1. 663951006441 HMMPfam hit to PF00120, Gln-synt_C, score 1.2e-151 663951006442 PS00181 Glutamine synthetase putative ATP-binding region signature. 663951006443 Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cl17200 663951006444 Predicted helix-turn-helix motif with score 1336.000, SD 3.74 at aa 16-37, sequence LTGYEISKKTGVSQYVLSQLRQ 663951006445 Phage Mu protein F like protein; Region: Phage_Mu_F; cl10072 663951006446 HMMPfam hit to PF04233, Phage_Mu_F, score 1.2e-12 663951006447 Transposase, Mutator family; Region: Transposase_mut; pfam00872 663951006448 MULE transposase domain; Region: MULE; pfam10551 663951006449 HMMPfam hit to PF00872, Transposase_mut, score 9.8e-228 663951006450 PS01007 Transposases, Mutator family, signature. 663951006451 Phage Mu protein F like protein; Region: Phage_Mu_F; cl10072 663951006452 HMMPfam hit to PF01423, LSM, score 0.00099 663951006453 Threonine aldolase [Amino acid transport and metabolism]; Region: GLY1; COG2008 663951006454 Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321 663951006455 pyridoxal 5'-phosphate binding pocket [chemical binding]; other site 663951006456 catalytic residue [active] 663951006457 HMMPfam hit to PF01212, Beta_elim_lyase, score 6.6e-36 663951006458 cardiolipin synthase; Region: bac_cardiolipin; TIGR04265 663951006459 Phospholipase_D-nuclease N-terminal; Region: PLDc_N; pfam13396 663951006460 Catalytic domain, repeat 1, of bacterial cardiolipin synthase and similar proteins; Region: PLDc_CLS_1; cd09110 663951006461 putative active site [active] 663951006462 catalytic site [active] 663951006463 catalytic domain repeat 2 of bacterial cardiolipin synthase and similar proteins; Region: PLDc_CLS_2; cd09112 663951006464 putative active site [active] 663951006465 catalytic site [active] 663951006466 2 probable transmembrane helices predicted for SATW20_13200 by TMHMM2.0 at aa 10-32 and 44-66 663951006467 HMMPfam hit to PF00614, PLDc, score 8.7e-09 663951006468 HMMPfam hit to PF00614, PLDc, score 6.1e-07 663951006469 ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131 663951006470 ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230 663951006471 Walker A/P-loop; other site 663951006472 ATP binding site [chemical binding]; other site 663951006473 Q-loop/lid; other site 663951006474 ABC transporter signature motif; other site 663951006475 Walker B; other site 663951006476 D-loop; other site 663951006477 H-loop/switch region; other site 663951006478 HMMPfam hit to PF00005, ABC_tran, score 3.2e-34 663951006479 PS00017 ATP/GTP-binding site motif A (P-loop). 663951006480 PS00211 ABC transporters family signature. 663951006481 ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842 663951006482 HMMPfam hit to PF01061, ABC2_membrane, score 0.00049 663951006483 6 probable transmembrane helices predicted for SATW20_13220 by TMHMM2.0 at aa 20-37, 52-74, 95-117,137-156, 163-182 and 214-236 663951006484 Signal transduction histidine kinase [Signal transduction mechanisms]; Region: COG4585 663951006485 Histidine kinase; Region: HisKA_3; pfam07730 663951006486 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Region: HATPase_c; pfam02518 663951006487 5 probable transmembrane helices predicted for SATW20_13230 by TMHMM2.0 at aa 12-31, 35-54, 61-83, 87-104 and 124-146 663951006488 HMMPfam hit to PF07730, HisKA_3, score 1.2e-20 663951006489 Predicted helix-turn-helix motif with score 1050.000, SD 2.76 at aa 272-293, sequence LSPTKQSMLVMITREAINNVIK 663951006490 HMMPfam hit to PF02518, HATPase_c, score 6.2e-08 663951006491 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197 663951006492 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 663951006493 active site 663951006494 phosphorylation site [posttranslational modification] 663951006495 intermolecular recognition site; other site 663951006496 dimerization interface [polypeptide binding]; other site 663951006497 C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170 663951006498 DNA binding residues [nucleotide binding] 663951006499 dimerization interface [polypeptide binding]; other site 663951006500 HMMPfam hit to PF00072, Response_reg, score 1.4e-27 663951006501 HMMPfam hit to PF00196, GerE, score 3.1e-11 663951006502 Predicted helix-turn-helix motif with score 1371.000, SD 3.86 at aa 155-176, sequence LSSKEISEKLFLTDGTVRNYTS 663951006503 2 probable transmembrane helices predicted for SATW20_13250 by TMHMM2.0 at aa 9-28 and 32-54 663951006504 Staphylococcal nuclease homologues; Region: SNc; smart00318 663951006505 Staphylococcal nuclease homologues. SNase homologues are found in bacteria, archaea, and eukaryotes. They contain no disufide bonds; Region: SNc; cd00175 663951006506 Catalytic site; other site 663951006507 1 probable transmembrane helix predicted for SATW20_13260 by TMHMM2.0 at aa 7-24 663951006508 HMMPfam hit to PF00565, SNase, score 2.8e-50 663951006509 PS01284 Thermonuclease family signature 2. 663951006510 AAA domain; Region: AAA_11; pfam13086 663951006511 1 probable transmembrane helix predicted for SATW20_13270 by TMHMM2.0 at aa 4-21 663951006512 aspartate kinase; Reviewed; Region: PRK09034 663951006513 AAK_AKiii-YclM-BS: Amino Acid Kinase Superfamily (AAK), AKiii-YclM-BS; this CD includes the N-terminal catalytic aspartokinase (AK) domain of the lysine plus threonine-sensitive aspartokinase isoenzyme AKIII, a monofunctional class enzyme found in...; Region: AAK_AKiii-YclM-BS; cd04245 663951006514 putative catalytic residues [active] 663951006515 putative nucleotide binding site [chemical binding]; other site 663951006516 putative aspartate binding site [chemical binding]; other site 663951006517 ACT domains located C-terminal to the catalytic domain of the lysine plus threonine-sensitive aspartokinase isoenzyme AKIII; Region: ACT_AKiii-YclM-BS_1; cd04911 663951006518 allosteric regulatory residue; other site 663951006519 ACT domains located C-terminal to the catalytic domain of the lysine plus threonine-sensitive aspartokinase isoenzyme AKIII; Region: ACT_AKiii-YclM-BS_2; cd04916 663951006520 HMMPfam hit to PF01842, ACT, score 0.029 663951006521 HMMPfam hit to PF01842, ACT, score 0.37 663951006522 HMMPfam hit to PF00696, AA_kinase, score 3.9e-35 663951006523 PS00324 Aspartokinase signature. 663951006524 Homoserine dehydrogenase [Amino acid transport and metabolism]; Region: ThrA; COG0460 663951006525 Homoserine dehydrogenase, NAD binding domain; Region: NAD_binding_3; pfam03447 663951006526 Homoserine dehydrogenase; Region: Homoserine_dh; pfam00742 663951006527 HMMPfam hit to PF03447, NAD_binding_3, score 1.3e-23 663951006528 HMMPfam hit to PF00742, Homoserine_dh, score 6.3e-73 663951006529 PS01042 Homoserine dehydrogenase signature. 663951006530 threonine synthase; Reviewed; Region: PRK06721 663951006531 Threonine synthase is a pyridoxal phosphate (PLP) dependent enzyme that catalyses the last reaction in the synthesis of threonine from aspartate. It proceeds by converting O-phospho-L-homoserine (OPH) into threonine and inorganic phosphate. In plants; Region: Thr-synth_1; cd01563 663951006532 homodimer interface [polypeptide binding]; other site 663951006533 pyridoxal 5'-phosphate binding site [chemical binding]; other site 663951006534 catalytic residue [active] 663951006535 HMMPfam hit to PF00291, PALP, score 2.2e-93 663951006536 PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 663951006537 homoserine kinase; Provisional; Region: PRK01212 663951006538 GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288 663951006539 GHMP kinases C terminal; Region: GHMP_kinases_C; pfam08544 663951006540 HMMPfam hit to PF00288, GHMP_kinases_N, score 5.1e-20 663951006541 PS00627 GHMP kinases putative ATP-binding domain. 663951006542 HMMPfam hit to PF08544, GHMP_kinases_C, score 1.9e-06 663951006543 Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427 663951006544 haloacid dehalogenase-like hydrolase; Region: Hydrolase_3; pfam08282 663951006545 active site 663951006546 motif I; other site 663951006547 motif II; other site 663951006548 haloacid dehalogenase-like hydrolase; Region: HAD; cl17202 663951006549 HMMPfam hit to PF08282, Hydrolase_3, score 2.1e-87 663951006550 lysine transporter; Provisional; Region: PRK10836 663951006551 HMMPfam hit to PF00324, AA_permease, score 3.7e-146 663951006552 11 probable transmembrane helices predicted for SATW20_13350 by TMHMM2.0 at aa 15-37, 44-66, 93-115,122-144, 159-181, 239-261, 284-306, 338-357, 367-389,409-431 and 446-463 663951006553 PS00218 Amino acid permeases signature. 663951006554 Catalase [Inorganic ion transport and metabolism]; Region: KatE; COG0753 663951006555 Clade 3 of the heme-binding enzyme catalase; Region: catalase_clade_3; cd08156 663951006556 tetramer interface [polypeptide binding]; other site 663951006557 heme binding pocket [chemical binding]; other site 663951006558 NADPH binding site [chemical binding]; other site 663951006559 HMMPfam hit to PF00199, Catalase, score 4e-262 663951006560 PS00438 Catalase proximal active site signature. 663951006561 PS00437 Catalase proximal heme-ligand signature. 663951006562 50S ribosomal protein L33; Validated; Region: rpmG; PRK00595 663951006563 HMMPfam hit to PF00471, Ribosomal_L33, score 4.2e-24 663951006564 PS00582 Ribosomal protein L33 signature. 663951006565 30S ribosomal protein S14; Reviewed; Region: rpsN; PRK08881 663951006566 HMMPfam hit to PF00253, Ribosomal_S14, score 2.1e-25 663951006567 PS00527 Ribosomal protein S14 signature. 663951006568 guanosine 5'-monophosphate oxidoreductase; Provisional; Region: PRK05458 663951006569 IMPDH: The catalytic domain of the inosine monophosphate dehydrogenase. IMPDH catalyzes the NAD-dependent oxidation of inosine 5'-monophosphate (IMP) to xanthosine 5' monophosphate (XMP). It is a rate-limiting step in the de novo synthesis of...; Region: IMPDH; cd00381 663951006570 active site 663951006571 HMMPfam hit to PF00478, IMPDH, score 6.2e-142 663951006572 Uncharacterized protein with SCP/PR1 domains [Function unknown]; Region: COG2340 663951006573 SCP_bacterial: SCP-like extracellular protein domain, as found in bacteria and archaea. The wider family of SCP containing proteins includes plant pathogenesis-related protein 1 (PR-1), CRISPs, mammalian cysteine-rich secretory proteins, and allergen 5...; Region: SCP_bacterial; cd05379 663951006574 HMMPfam hit to PF00188, SCP, score 2.4e-22 663951006575 LexA repressor; Validated; Region: PRK00215 663951006576 Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090 663951006577 putative DNA binding site [nucleotide binding]; other site 663951006578 putative Zn2+ binding site [ion binding]; other site 663951006579 Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529 663951006580 Catalytic site [active] 663951006581 HMMPfam hit to PF00717, Peptidase_S24, score 4.2e-23 663951006582 HMMPfam hit to PF01726, LexA_DNA_bind, score 1.5e-40 663951006583 PS00228 Tubulin-beta mRNA autoregulation signal. 663951006584 1 probable transmembrane helix predicted for SATW20_13420 by TMHMM2.0 at aa 13-35 663951006585 Bacterial protein of unknown function (DUF896); Region: DUF896; pfam05979 663951006586 HMMPfam hit to PF05979, DUF896, score 3.2e-44 663951006587 Transketolase [Carbohydrate transport and metabolism]; Region: TktA; COG0021 663951006588 Thiamine pyrophosphate (TPP) family, Transketolase (TK) subfamily, TPP-binding module; TK catalyzes the transfer of a two-carbon unit from ketose phosphates to aldose phosphates. In heterotrophic organisms, TK provides a link between glycolysis and the...; Region: TPP_TK; cd02012 663951006589 TPP-binding site [chemical binding]; other site 663951006590 dimer interface [polypeptide binding]; other site 663951006591 Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033 663951006592 PYR/PP interface [polypeptide binding]; other site 663951006593 dimer interface [polypeptide binding]; other site 663951006594 TPP binding site [chemical binding]; other site 663951006595 Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780 663951006596 HMMPfam hit to PF00456, Transketolase_N, score 6e-191 663951006597 PS00801 Transketolase signature 1. 663951006598 HMMPfam hit to PF02779, Transket_pyr, score 8.6e-59 663951006599 PS00802 Transketolase signature 2. 663951006600 HMMPfam hit to PF02780, Transketolase_C, score 0.0016 663951006601 Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3763 663951006602 1 probable transmembrane helix predicted for SATW20_13450 by TMHMM2.0 at aa 4-26 663951006603 HMMPfam hit to PF03672, UPF0154, score 4.7e-28 663951006604 Membrane protein involved in cytochrome C biogenesis [Posttranslational modification, protein turnover, chaperones]; Region: CcdC; COG4846 663951006605 HMMPfam hit to PF07301, DUF1453, score 5.8e-110 663951006606 5 probable transmembrane helices predicted for SATW20_13460 by TMHMM2.0 at aa 4-21, 34-56, 61-83, 95-114 and 124-143 663951006607 DNA repair exonuclease [DNA replication, recombination, and repair]; Region: SbcD; COG0420 663951006608 Mre11 nuclease, N-terminal metallophosphatase domain; Region: MPP_Mre11_N; cd00840 663951006609 active site 663951006610 metal binding site [ion binding]; metal-binding site 663951006611 DNA binding site [nucleotide binding] 663951006612 Type 5 capsule protein repressor C-terminal domain; Region: SbcD_C; pfam12320 663951006613 HMMPfam hit to PF00149, Metallophos, score 1.4e-17 663951006614 ATPase involved in DNA repair [DNA replication, recombination, and repair]; Region: SbcC; COG0419 663951006615 ATP-binding cassette domain of sbcCD; Region: ABC_sbcCD; cd03279 663951006616 Walker A/P-loop; other site 663951006617 ATP binding site [chemical binding]; other site 663951006618 Q-loop/lid; other site 663951006619 ATP-binding cassette domain of sbcCD; Region: ABC_sbcCD; cd03279 663951006620 ABC transporter signature motif; other site 663951006621 Walker B; other site 663951006622 D-loop; other site 663951006623 H-loop/switch region; other site 663951006624 PS00017 ATP/GTP-binding site motif A (P-loop). 663951006625 large-conductance mechanosensitive channel; Reviewed; Region: mscL; PRK00567 663951006626 large-conductance mechanosensitive channel; Provisional; Region: mscL; PRK13954 663951006627 HMMPfam hit to PF01741, MscL, score 1.5e-75 663951006628 2 probable transmembrane helices predicted for SATW20_13490 by TMHMM2.0 at aa 13-35 and 65-84 663951006629 PS01327 Large-conductance mechanosensitive channels mscL family signature. 663951006630 Choline-glycine betaine transporter [Cell envelope biogenesis, outer membrane]; Region: BetT; COG1292 663951006631 11 probable transmembrane helices predicted for SATW20_13500 by TMHMM2.0 at aa 15-35, 56-78, 93-115,190-212, 232-254, 263-285, 321-340, 353-375, 400-422,443-465 and 475-497 663951006632 HMMPfam hit to PF02028, BCCT, score 6.7e-225 663951006633 PS01303 BCCT family of transporters signature. 663951006634 aconitate hydratase; Validated; Region: PRK09277 663951006635 Aconitase A catalytic domain; Region: AcnA_IRP; cd01586 663951006636 substrate binding site [chemical binding]; other site 663951006637 ligand binding site [chemical binding]; other site 663951006638 Aconitase A swivel domain. This is the major form of the TCA cycle enzyme aconitate hydratase, also known as aconitase and citrate hydro-lyase. It includes bacterial and archaeal aconitase A, and the eukaryotic cytosolic form of aconitase. This group...; Region: AcnA_IRP_Swivel; cd01580 663951006639 substrate binding site [chemical binding]; other site 663951006640 HMMPfam hit to PF00330, Aconitase, score 5.7e-197 663951006641 PS00450 Aconitase family signature 1. 663951006642 PS01244 Aconitase family signature 2. 663951006643 HMMPfam hit to PF00694, Aconitase_C, score 1.4e-52 663951006644 4-hydroxybenzoyl-CoA thioesterase (4HBT). Catalyzes the final step in the 4-chlorobenzoate degradation pathway in which 4-chlorobenzoate is converted to 4-hydroxybenzoate in certain soil-dwelling bacteria. 4HBT forms a homotetramer with four active sites; Region: 4HBT; cd00586 663951006645 active site 663951006646 HMMPfam hit to PF03061, 4HBT, score 2e-21 663951006647 Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4841 663951006648 HMMPfam hit to PF01521, Fe-S_biosyn, score 1.8e-32 663951006649 putative glycerol-3-phosphate acyltransferase PlsY; Provisional; Region: PRK00220 663951006650 HMMPfam hit to PF02660, DUF205, score 1.5e-67 663951006651 5 probable transmembrane helices predicted for SATW20_13540 by TMHMM2.0 at aa 4-26, 52-74, 84-106, 118-140 and 150-182 663951006652 DNA gyrase subunit B; Validated; Region: gyrB; PRK05644 663951006653 Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075 663951006654 ATP binding site [chemical binding]; other site 663951006655 Mg2+ binding site [ion binding]; other site 663951006656 G-X-G motif; other site 663951006657 TopoIIA_Trans_DNA_gyrase: Transducer domain, having a ribosomal S5 domain 2-like fold, of the type found in proteins of the type IIA family of DNA topoisomerases similar to the B subunits of E. coli DNA gyrase and E. coli Topoisomerase IV which are; Region: TopoII_Trans_DNA_gyrase; cd00822 663951006658 anchoring element; other site 663951006659 dimer interface [polypeptide binding]; other site 663951006660 ATP binding site [chemical binding]; other site 663951006661 TOPRIM_TopoIIA_GyrB: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in proteins of the type IIA family of DNA topoisomerases similar to the Escherichia coli GyrB subunit. TopoIIA enzymes cut both strands of the...; Region: TOPRIM_TopoIIA_GyrB; cd03366 663951006662 active site 663951006663 putative metal-binding site [ion binding]; other site 663951006664 DNA gyrase B subunit, carboxyl terminus; Region: DNA_gyraseB_C; pfam00986 663951006665 HMMPfam hit to PF02518, HATPase_c, score 1.2e-32 663951006666 PS00017 ATP/GTP-binding site motif A (P-loop). 663951006667 HMMPfam hit to PF00204, DNA_gyraseB, score 8.8e-92 663951006668 HMMPfam hit to PF01751, Toprim, score 2.1e-06 663951006669 PS00177 DNA topoisomerase II signature. 663951006670 HMMPfam hit to PF00986, DNA_gyraseB_C, score 2.9e-44 663951006671 DNA topoisomerase IV subunit A; Validated; Region: PRK05561 663951006672 DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes...; Region: TOP4c; cd00187 663951006673 CAP-like domain; other site 663951006674 active site 663951006675 primary dimer interface [polypeptide binding]; other site 663951006676 DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989 663951006677 HMMPfam hit to PF00521, DNA_topoisoIV, score 2.1e-297 663951006678 HMMPfam hit to PF03989, DNA_gyraseA_C, score 2.4e-05 663951006679 HMMPfam hit to PF03989, DNA_gyraseA_C, score 7.6e-06 663951006680 HMMPfam hit to PF03989, DNA_gyraseA_C, score 4.5e-06 663951006681 HMMPfam hit to PF03989, DNA_gyraseA_C, score 6.9e-06 663951006682 HMMPfam hit to PF03989, DNA_gyraseA_C, score 9.9e-07 663951006683 Na+/alanine symporter [Amino acid transport and metabolism]; Region: AlsT; COG1115 663951006684 amino acid carrier protein; Region: agcS; TIGR00835 663951006685 9 probable transmembrane helices predicted for SATW20_13570 by TMHMM2.0 at aa 22-41, 90-112, 155-172,193-215, 219-241, 309-331, 357-379, 392-411 and 422-444 663951006686 HMMPfam hit to PF01235, Na_Ala_symp, score 2.8e-205 663951006687 PS00873 Sodium:alanine symporter family signature. 663951006688 CAT RNA binding domain; Region: CAT_RBD; smart01061 663951006689 Transcriptional antiterminator [Transcription]; Region: BglG; COG3711 663951006690 PRD domain; Region: PRD; pfam00874 663951006691 PRD domain; Region: PRD; pfam00874 663951006692 HMMPfam hit to PF03123, CAT_RBD, score 2.6e-23 663951006693 HMMPfam hit to PF00874, PRD, score 4.4e-16 663951006694 PS00654 Transcriptional antiterminators bglG family signature. 663951006695 HMMPfam hit to PF00874, PRD, score 9.8e-14 663951006696 Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; COG0628 663951006697 Domain of unknown function DUF20; Region: UPF0118; pfam01594 663951006698 8 probable transmembrane helices predicted for SATW20_13590 by TMHMM2.0 at aa 9-26, 36-58, 75-97, 162-184,222-244, 249-271, 276-298 and 318-340 663951006699 HMMPfam hit to PF01594, UPF0118, score 2.2e-88 663951006700 Predicted integral membrane protein [Function unknown]; Region: COG0392 663951006701 Uncharacterized conserved protein [Function unknown]; Region: COG2898 663951006702 Uncharacterized conserved protein (DUF2156); Region: DUF2156; pfam09924 663951006703 14 probable transmembrane helices predicted for SATW20_13600 by TMHMM2.0 at aa 9-31, 51-73, 94-116,131-153, 162-184, 194-216, 229-251, 271-293, 336-358,368-390, 397-416, 420-439, 451-473 and 488-510 663951006704 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 663951006705 HMMPfam hit to PF03706, UPF0104, score 1.1e-05 663951006706 HMMPfam hit to PF04329, DUF470, score 2.9e-77 663951006707 HMMPfam hit to PF04330, DUF471, score 9.3e-33 663951006708 HMMPfam hit to PF04331, DUF472, score 6.4e-52 663951006709 methionine sulfoxide reductase A; Provisional; Region: PRK14054 663951006710 HMMPfam hit to PF01625, PMSR, score 3.1e-75 663951006711 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 663951006712 Transcriptional regulator [Transcription]; Region: LytR; COG1316 663951006713 1 probable transmembrane helix predicted for SATW20_13620 by TMHMM2.0 at aa 32-54 663951006714 HMMPfam hit to PF03816, LytR_cpsA_psr, score 1e-78 663951006715 4-Oxalocrotonate Tautomerase: Catalyzes the isomerization of unsaturated ketones. The structure is a homohexamer that is arranged as a trimer of dimers. The hexamer contains six active sites, each formed by residues from three monomers, two from one...; Region: 4Oxalocrotonate_Tautomerase; cd00491 663951006716 active site 1 [active] 663951006717 dimer interface [polypeptide binding]; other site 663951006718 hexamer interface [polypeptide binding]; other site 663951006719 active site 2 [active] 663951006720 HMMPfam hit to PF01361, Tautomerase, score 1.3e-29 663951006721 Nucleotidyltransferase/DNA polymerase involved in DNA repair [DNA replication, recombination, and repair]; Region: DinP; COG0389 663951006722 umuC subunit of DNA Polymerase V; Region: PolY_Pol_V_umuC; cd01700 663951006723 active site 663951006724 DNA binding site [nucleotide binding] 663951006725 Domain of unknown function (DUF4113); Region: DUF4113; pfam13438 663951006726 HMMPfam hit to PF00817, IMS, score 2.2e-89 663951006727 prephenate dehydrogenase; Validated; Region: PRK06545 663951006728 prephenate dehydrogenase; Validated; Region: PRK08507 663951006729 C-terminal ACT domain of the monofunctional, NAD dependent, prephenate dehydrogenase (PDH); Region: ACT_PDH-BS; cd04909 663951006730 PS00294 Prenyl group binding site (CAAX box). 663951006731 HMMPfam hit to PF02153, PDH, score 5.3e-88 663951006732 Cellulase M and related proteins [Carbohydrate transport and metabolism]; Region: FrvX; COG1363 663951006733 M42 Peptidase, Endoglucanase-like subfamily; Region: M42_glucanase_like; cd05657 663951006734 putative oligomer interface [polypeptide binding]; other site 663951006735 putative active site [active] 663951006736 metal binding site [ion binding]; metal-binding site 663951006737 HMMPfam hit to PF05343, Peptidase_M42, score 2.9e-122 663951006738 anthranilate synthase component I; Provisional; Region: PRK13567 663951006739 Anthranilate synthase component I, N terminal region; Region: Anth_synt_I_N; pfam04715 663951006740 chorismate binding enzyme; Region: Chorismate_bind; pfam00425 663951006741 HMMPfam hit to PF04715, Anth_synt_I_N, score 8.4e-30 663951006742 HMMPfam hit to PF00425, Chorismate_bind, score 6.4e-114 663951006743 Type 1 glutamine amidotransferase (GATase1) domain found in Anthranilate synthase; Region: GATase1_Anthranilate_Synthase; cd01743 663951006744 Glutamine amidotransferase class-I; Region: GATase; pfam00117 663951006745 glutamine binding [chemical binding]; other site 663951006746 catalytic triad [active] 663951006747 HMMPfam hit to PF00117, GATase, score 9.8e-42 663951006748 PS00442 Glutamine amidotransferases class-I active site. 663951006749 anthranilate phosphoribosyltransferase; Provisional; Region: trpD; PRK00188 663951006750 Glycosyl transferase family, a/b domain; Region: Glycos_transf_3; pfam00591 663951006751 HMMPfam hit to PF00591, Glycos_transf_3, score 2e-91 663951006752 Indole-3-glycerol phosphate synthase (IGPS); an enzyme in the tryptophan biosynthetic pathway, catalyzing the ring closure reaction of 1-(o-carboxyphenylamino)-1-deoxyribulose-5-phosphate (CdRP) to indole-3-glycerol phosphate (IGP), accompanied by the...; Region: IGPS; cd00331 663951006753 active site 663951006754 ribulose/triose binding site [chemical binding]; other site 663951006755 phosphate binding site [ion binding]; other site 663951006756 substrate (anthranilate) binding pocket [chemical binding]; other site 663951006757 product (indole) binding pocket [chemical binding]; other site 663951006758 HMMPfam hit to PF00218, IGPS, score 5.3e-80 663951006759 PS00614 Indole-3-glycerol phosphate synthase signature. 663951006760 PS00339 Aminoacyl-transfer RNA synthetases class-II signature 2. 663951006761 Phosphoribosylanthranilate isomerase (PRAI) catalyzes the fourth step of the tryptophan biosynthesis, the conversion of N-(5'- phosphoribosyl)-anthranilate (PRA) to 1-(o-carboxyphenylamino)- 1-deoxyribulose 5-phosphate (CdRP). Most PRAIs are...; Region: PRAI; cd00405 663951006762 active site 663951006763 HMMPfam hit to PF00697, PRAI, score 2e-32 663951006764 tryptophan synthase, beta subunit; Region: trpB; TIGR00263 663951006765 Tryptophan synthase-beta: Trptophan synthase is a bifunctional enzyme that catalyses the last two steps in the biosynthesis of L-tryptophan via its alpha and beta reactions. In the alpha reaction, indole 3-glycerol phosphate is cleaved reversibly to...; Region: Trp-synth_B; cd06446 663951006766 pyridoxal 5'-phosphate binding site [chemical binding]; other site 663951006767 catalytic residue [active] 663951006768 HMMPfam hit to PF00291, PALP, score 1.9e-115 663951006769 PS00168 Tryptophan synthase beta chain pyridoxal-phosphate attachment site. 663951006770 tryptophan synthase alpha subunit; Provisional; Region: trpA; CHL00200 663951006771 Ttryptophan synthase (TRPS) alpha subunit (TSA). TPRS is a bifunctional tetrameric enzyme (2 alpha and 2 beta subunits) that catalyzes the last two steps of L-tryptophan biosynthesis. Alpha and beta subunit catalyze two distinct reactions which are both...; Region: Tryptophan_synthase_alpha; cd04724 663951006772 substrate binding site [chemical binding]; other site 663951006773 active site 663951006774 catalytic residues [active] 663951006775 heterodimer interface [polypeptide binding]; other site 663951006776 HMMPfam hit to PF00290, Trp_syntA, score 3.1e-63 663951006777 PS00167 Tryptophan synthase alpha chain signature. 663951006778 FemAB family; Region: FemAB; pfam02388 663951006779 FlxA-like protein; Region: FlxA; pfam14282 663951006780 HMMPfam hit to PF02388, FemAB, score 2.1e-268 663951006781 FemAB family; Region: FemAB; pfam02388 663951006782 HMMPfam hit to PF02388, FemAB, score 1.1e-240 663951006783 Cof subfamily of IIB subfamily of haloacid dehalogenase superfamily; Region: Cof-subfamily; TIGR00099 663951006784 Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427 663951006785 active site 663951006786 motif I; other site 663951006787 motif II; other site 663951006788 HMMPfam hit to PF08282, Hydrolase_3, score 5.6e-33 663951006789 SWIM zinc finger; Region: SWIM; pfam04434 663951006790 HMMPfam hit to PF04434, SWIM, score 3.5e-06 663951006791 ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppF; COG1124 663951006792 ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257 663951006793 Walker A/P-loop; other site 663951006794 ATP binding site [chemical binding]; other site 663951006795 Q-loop/lid; other site 663951006796 ABC transporter signature motif; other site 663951006797 Walker B; other site 663951006798 D-loop; other site 663951006799 H-loop/switch region; other site 663951006800 HMMPfam hit to PF00005, ABC_tran, score 5.5e-39 663951006801 PS00017 ATP/GTP-binding site motif A (P-loop). 663951006802 ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257 663951006803 nickel import ATP-binding protein NikD; Region: nickel_nikD; TIGR02770 663951006804 Walker A/P-loop; other site 663951006805 ATP binding site [chemical binding]; other site 663951006806 Q-loop/lid; other site 663951006807 ABC transporter signature motif; other site 663951006808 Walker B; other site 663951006809 D-loop; other site 663951006810 H-loop/switch region; other site 663951006811 HMMPfam hit to PF00005, ABC_tran, score 2.4e-33 663951006812 PS00017 ATP/GTP-binding site motif A (P-loop). 663951006813 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppC; COG1173 663951006814 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 663951006815 dimer interface [polypeptide binding]; other site 663951006816 conserved gate region; other site 663951006817 putative PBP binding loops; other site 663951006818 ABC-ATPase subunit interface; other site 663951006819 HMMPfam hit to PF00528, BPD_transp_1, score 7.1e-52 663951006820 4 probable transmembrane helices predicted for SATW20_13800 by TMHMM2.0 at aa 25-47, 67-89, 142-164 and 184-206 663951006821 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601 663951006822 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 663951006823 dimer interface [polypeptide binding]; other site 663951006824 conserved gate region; other site 663951006825 putative PBP binding loops; other site 663951006826 ABC-ATPase subunit interface; other site 663951006827 HMMPfam hit to PF00528, BPD_transp_1, score 2e-52 663951006828 6 probable transmembrane helices predicted for SATW20_13810 by TMHMM2.0 at aa 7-29, 104-126, 139-161,171-193, 228-250 and 278-300 663951006829 PS00402 Binding-protein-dependent transport systems inner membrane comp. sign. 663951006830 bifunctional preprotein translocase subunit SecD/SecF; Provisional; Region: PRK14726 663951006831 3 probable transmembrane helices predicted for SATW20_13820 by TMHMM2.0 at aa 10-29, 31-50 and 60-82 663951006832 oligoendopeptidase F; Region: pepF; TIGR00181 663951006833 Peptidase family M3B Oligopeptidase F (PepF); Region: M3B_PepF_4; cd09609 663951006834 active site 663951006835 Zn binding site [ion binding]; other site 663951006836 HMMPfam hit to PF08439, Peptidase_M3_N, score 1.1e-22 663951006837 HMMPfam hit to PF01432, Peptidase_M3, score 1e-39 663951006838 PS00142 Neutral zinc metallopeptidases, zinc-binding region signature. 663951006839 phosphate transport system regulatory protein PhoU; Region: phoU_full; TIGR02135 663951006840 PhoU domain; Region: PhoU; pfam01895 663951006841 PhoU domain; Region: PhoU; pfam01895 663951006842 HMMPfam hit to PF01895, PhoU, score 2.3e-20 663951006843 HMMPfam hit to PF01895, PhoU, score 5.7e-17 663951006844 phosphate transporter ATP-binding protein; Provisional; Region: PRK14238 663951006845 ATP-binding cassette domain of the phosphate transport system; Region: ABC_PstB_phosphate_transporter; cd03260 663951006846 Walker A/P-loop; other site 663951006847 ATP binding site [chemical binding]; other site 663951006848 Q-loop/lid; other site 663951006849 ABC transporter signature motif; other site 663951006850 Walker B; other site 663951006851 D-loop; other site 663951006852 H-loop/switch region; other site 663951006853 HMMPfam hit to PF00005, ABC_tran, score 5.1e-57 663951006854 PS00211 ABC transporters family signature. 663951006855 PS00017 ATP/GTP-binding site motif A (P-loop). 663951006856 phosphate ABC transporter, permease protein PstA; Region: 3a0107s02c; TIGR00974 663951006857 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 663951006858 dimer interface [polypeptide binding]; other site 663951006859 conserved gate region; other site 663951006860 putative PBP binding loops; other site 663951006861 ABC-ATPase subunit interface; other site 663951006862 HMMPfam hit to PF00528, BPD_transp_1, score 2.5e-21 663951006863 6 probable transmembrane helices predicted for SATW20_13860 by TMHMM2.0 at aa 33-55, 86-108, 128-150,155-177, 207-229 and 275-297 663951006864 PS00402 Binding-protein-dependent transport systems inner membrane comp. sign. 663951006865 ABC-type phosphate transport system, permease component [Inorganic ion transport and metabolism]; Region: PstC; COG0573 663951006866 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 663951006867 dimer interface [polypeptide binding]; other site 663951006868 conserved gate region; other site 663951006869 ABC-ATPase subunit interface; other site 663951006870 HMMPfam hit to PF00528, BPD_transp_1, score 6.5e-24 663951006871 6 probable transmembrane helices predicted for SATW20_13870 by TMHMM2.0 at aa 25-47, 79-111, 124-146,161-180, 209-231 and 275-297 663951006872 PS00402 Binding-protein-dependent transport systems inner membrane comp. sign. 663951006873 phosphate binding protein; Region: ptsS_2; TIGR02136 663951006874 HMMPfam hit to PF01547, SBP_bac_1, score 2.8e-05 663951006875 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 663951006876 Probable gene remnant 663951006877 HMMPfam hit to PF01609, Transposase_11, score 3.4e-09 663951006878 Predicted RNA-bindining protein (contains S1 and HTH domains) [General function prediction only]; Region: COG2996 663951006879 S1 domain; Region: S1_2; pfam13509 663951006880 ABC transporter ATP-binding protein; Provisional; Region: PRK15064 663951006881 ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221 663951006882 ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221 663951006883 ABC transporter; Region: ABC_tran_2; pfam12848 663951006884 ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221 663951006885 HMMPfam hit to PF00005, ABC_tran, score 4e-36 663951006886 PS00017 ATP/GTP-binding site motif A (P-loop). 663951006887 HMMPfam hit to PF00005, ABC_tran, score 3.4e-25 663951006888 aspartate kinase; Reviewed; Region: PRK06635 663951006889 AAK_AKii-LysC-BS: Amino Acid Kinase Superfamily (AAK), AKii; this CD includes the N-terminal catalytic aspartokinase (AK) domain of the lysine-sensitive aspartokinase isoenzyme AKII of Bacillus subtilis 168, and the lysine plus threonine-sensitive...; Region: AAK_AKii-LysC-BS; cd04261 663951006890 putative nucleotide binding site [chemical binding]; other site 663951006891 putative catalytic residues [active] 663951006892 putative Mg ion binding site [ion binding]; other site 663951006893 putative aspartate binding site [chemical binding]; other site 663951006894 ACT domains of the lysine-sensitive aspartokinase isoenzyme AKII and related proteins; Region: ACT_AK-LysC-DapG-like_1; cd04891 663951006895 ACT domains of the lysine-sensitive aspartokinase isoenzyme AKII of Bacillus subtilis (BS) strain 168 and related domains; Region: ACT_AK-LysC-DapG-like_2; cd04923 663951006896 HMMPfam hit to PF00696, AA_kinase, score 7.4e-47 663951006897 PS00324 Aspartokinase signature. 663951006898 aspartate-semialdehyde dehydrogenase; Provisional; Region: PRK14874 663951006899 Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859 663951006900 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; pfam02800 663951006901 HMMPfam hit to PF01118, Semialdhyde_dh, score 7.9e-39 663951006902 HMMPfam hit to PF02774, Semialdhyde_dhC, score 1.2e-53 663951006903 Dihydrodipicolinate synthase/N-acetylneuraminate lyase [Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: DapA; COG0329 663951006904 Dihydrodipicolinate synthase (DHDPS); Region: DHDPS; cd00950 663951006905 dimer interface [polypeptide binding]; other site 663951006906 active site 663951006907 catalytic residue [active] 663951006908 HMMPfam hit to PF00701, DHDPS, score 6.5e-80 663951006909 PS00666 Dihydrodipicolinate synthetase signature 2. 663951006910 Dihydrodipicolinate reductase [Amino acid transport and metabolism]; Region: DapB; COG0289 663951006911 Dihydrodipicolinate reductase, N-terminus; Region: DapB_N; pfam01113 663951006912 Dihydrodipicolinate reductase, C-terminus; Region: DapB_C; pfam05173 663951006913 HMMPfam hit to PF01113, DapB_N, score 2.4e-23 663951006914 HMMPfam hit to PF05173, DapB_C, score 3.5e-65 663951006915 Tetrahydrodipicolinate succinyltransferase N-terminal; Region: DapH_N; pfam08503 663951006916 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase; Region: DapD_Ac; TIGR03532 663951006917 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate (THDP) N-succinyltransferase (also called THP succinyltransferase): THDP N-succinyltransferase catalyzes the conversion of tetrahydrodipicolinate and succinyl-CoA to N-succinyltetrahydrodipicolinate and CoA; Region: LbH_THP_succinylT; cd03350 663951006918 active site 663951006919 trimer interface [polypeptide binding]; other site 663951006920 substrate binding site [chemical binding]; other site 663951006921 CoA binding site [chemical binding]; other site 663951006922 HMMPfam hit to PF08503, DapD_N, score 2.6e-57 663951006923 HMMPfam hit to PF00132, Hexapep, score 4.6 663951006924 HMMPfam hit to PF00132, Hexapep, score 0.15 663951006925 HMMPfam hit to PF00132, Hexapep, score 8.5 663951006926 HMMPfam hit to PF00132, Hexapep, score 0.077 663951006927 PS00101 Hexapeptide-repeat containing-transferases signature. 663951006928 HMMPfam hit to PF00132, Hexapep, score 5.9 663951006929 Metal-dependent amidase/aminoacylase/carboxypeptidase [General function prediction only]; Region: AbgB; COG1473 663951006930 M20 Peptidase Aminoacylase 1 family; Region: M20_Acy1; cd03886 663951006931 metal binding site [ion binding]; metal-binding site 663951006932 dimer interface [polypeptide binding]; other site 663951006933 HMMPfam hit to PF01546, Peptidase_M20, score 1.7e-47 663951006934 Alanine racemase [Cell envelope biogenesis, outer membrane]; Region: Alr; COG0787 663951006935 Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes; Region: PLPDE_III; cl00261 663951006936 pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site 663951006937 catalytic residue [active] 663951006938 HMMPfam hit to PF01168, Ala_racemase_N, score 3.6e-60 663951006939 HMMPfam hit to PF00842, Ala_racemase_C, score 1.6e-39 663951006940 Diaminopimelate decarboxylase [Amino acid transport and metabolism]; Region: LysA; COG0019 663951006941 Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Diaminopimelate Decarboxylase; Region: PLPDE_III_DapDC; cd06828 663951006942 active site 663951006943 pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site 663951006944 substrate binding site [chemical binding]; other site 663951006945 catalytic residues [active] 663951006946 dimer interface [polypeptide binding]; other site 663951006947 HMMPfam hit to PF02784, Orn_Arg_deC_N, score 1.9e-77 663951006948 PS00879 Orn/DAP/Arg decarboxylases family 2 signature 2. 663951006949 HMMPfam hit to PF00278, Orn_DAP_Arg_deC, score 1.9e-35 663951006950 4 probable transmembrane helices predicted for SATW20_14000 by TMHMM2.0 at aa 3-21, 25-47, 54-76 and 108-125 663951006951 Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea. CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458 663951006952 DNA-binding site [nucleotide binding]; DNA binding site 663951006953 RNA-binding motif; other site 663951006954 PS00352 'Cold-shock' DNA-binding domain signature. 663951006955 Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4699 663951006956 HMMPfam hit to PF06279, DUF1033, score 3.8e-10 663951006957 acylphosphatase; Provisional; Region: PRK14431 663951006958 HMMPfam hit to PF00708, Acylphosphatase, score 1.2e-08 663951006959 PS00150 Acylphosphatase signature 1. 663951006960 5-bromo-4-chloroindolyl phosphate hydrolysis protein [General function prediction only]; Region: XpaC; COG4915 663951006961 2 probable transmembrane helices predicted for SATW20_14040 by TMHMM2.0 at aa 7-29 and 33-51 663951006962 Toxic anion resistance protein (TelA); Region: TelA; pfam05816 663951006963 HMMPfam hit to PF05816, TelA, score 7.3e-181 663951006964 CDS contains a frameshift after codon 121. Frameshift occurs at a poly A hexamer 663951006965 Branched-chain amino acid permeases [Amino acid transport and metabolism]; Region: BrnQ; COG1114 663951006966 HMMPfam hit to PF05525, Branch_AA_trans, score 3.7e-227 663951006967 12 probable transmembrane helices predicted for SATW20_14080 by TMHMM2.0 at aa 7-25, 35-57, 77-94, 109-131,143-160, 193-215, 228-250, 292-314, 321-338, 348-370,382-404 and 419-437 663951006968 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 663951006969 Nitric oxide reductase activation protein [Inorganic ion transport and metabolism]; Region: NorD; COG4548 663951006970 norD type: Denitrifying bacteria contain both membrane bound and periplasmic nitrate reductases. Denitrification plays a major role in completing the nitrogen cycle by converting nitrate or nitrite to nitrogen gas. The pathway for microbial...; Region: vWA_norD_type; cd01454 663951006971 metal ion-dependent adhesion site (MIDAS); other site 663951006972 MoxR-like ATPases [General function prediction only]; Region: COG0714 663951006973 The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009 663951006974 Walker A motif; other site 663951006975 ATP binding site [chemical binding]; other site 663951006976 Walker B motif; other site 663951006977 arginine finger; other site 663951006978 HMMPfam hit to PF07728, AAA_5, score 2.1e-35 663951006979 PS00017 ATP/GTP-binding site motif A (P-loop). 663951006980 This domain superfamily is found in a variety of structurally related metalloproteins, including the type I extradiol dioxygenases, glyoxalase I and a group of antibiotic resistance proteins; Region: Glo_EDI_BRP_like; cl14632 663951006981 active site 663951006982 This domain superfamily is found in a variety of structurally related metalloproteins, including the type I extradiol dioxygenases, glyoxalase I and a group of antibiotic resistance proteins; Region: Glo_EDI_BRP_like; cl14632 663951006983 active site 663951006984 HMMPfam hit to PF00903, Glyoxalase, score 0.0091 663951006985 dihydrolipoamide succinyltransferase; Validated; Region: PRK05704 663951006986 Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849 663951006987 E3 interaction surface; other site 663951006988 lipoyl attachment site [posttranslational modification]; other site 663951006989 e3 binding domain; Region: E3_binding; pfam02817 663951006990 2-oxoacid dehydrogenases acyltransferase (catalytic domain); Region: 2-oxoacid_dh; pfam00198 663951006991 HMMPfam hit to PF00198, 2-oxoacid_dh, score 1.6e-126 663951006992 HMMPfam hit to PF02817, E3_binding, score 0.00044 663951006993 HMMPfam hit to PF00364, Biotin_lipoyl, score 2.7e-28 663951006994 PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 663951006995 2-oxoglutarate dehydrogenase E1 component; Reviewed; Region: sucA; PRK09404 663951006996 Thiamine pyrophosphate (TPP) family, E1 of OGDC-like subfamily, TPP-binding module; composed of proteins similar to the E1 component of the 2-oxoglutarate dehydrogenase multienzyme complex (OGDC). OGDC catalyzes the oxidative decarboxylation of...; Region: TPP_E1_OGDC_like; cd02016 663951006997 TPP-binding site [chemical binding]; other site 663951006998 Ribosome recycling factor (RRF). Ribosome recycling factor dissociates the posttermination complex, composed of the ribosome, deacylated tRNA, and mRNA, after termination of translation. Thus ribosomes are "recycled" and ready for another...; Region: RRF; cl00240 663951006999 Transketolase, pyrimidine binding domain; Region: Transket_pyr; pfam02779 663951007000 HMMPfam hit to PF02779, Transket_pyr, score 2.2e-53 663951007001 HMMPfam hit to PF00676, E1_dh, score 1.2e-53 663951007002 Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642 663951007003 HAMP domain; Region: HAMP; pfam00672 663951007004 Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082 663951007005 dimer interface [polypeptide binding]; other site 663951007006 phosphorylation site [posttranslational modification] 663951007007 Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075 663951007008 ATP binding site [chemical binding]; other site 663951007009 Mg2+ binding site [ion binding]; other site 663951007010 G-X-G motif; other site 663951007011 HMMPfam hit to PF02518, HATPase_c, score 3.8e-34 663951007012 HMMPfam hit to PF00512, HisKA, score 4.3e-18 663951007013 HMMPfam hit to PF00672, HAMP, score 3.3e-09 663951007014 2 probable transmembrane helices predicted for SATW20_14150 by TMHMM2.0 at aa 10-32 and 154-176 663951007015 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745 663951007016 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 663951007017 active site 663951007018 phosphorylation site [posttranslational modification] 663951007019 intermolecular recognition site; other site 663951007020 dimerization interface [polypeptide binding]; other site 663951007021 Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383 663951007022 DNA binding site [nucleotide binding] 663951007023 HMMPfam hit to PF00486, Trans_reg_C, score 4.7e-24 663951007024 HMMPfam hit to PF00072, Response_reg, score 1.4e-45 663951007025 PS00217 Sugar transport proteins signature 2. 663951007026 Transposase IS200 like; Region: Y1_Tnp; pfam01797 663951007027 HMMPfam hit to PF01797, Transposase_17, score 8.4e-59 663951007028 Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671 663951007029 PAP2_like_2 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This subgroup, which is specific to bacteria, lacks functional characterization and may act as a membrane-associated lipid phosphatase; Region: PAP2_like_2; cd03392 663951007030 active site 663951007031 HMMPfam hit to PF01569, PAP2, score 1.6e-31 663951007032 6 probable transmembrane helices predicted for SATW20_14180 by TMHMM2.0 at aa 7-24, 58-77, 84-101,121-143, 150-172 and 176-198 663951007033 undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase; Reviewed; Region: PRK12446 663951007034 MurG is an N-acetylglucosaminyltransferase, the last enzyme involved in the intracellular phase of peptidoglycan biosynthesis. It transfers N-acetyl-D-glucosamine (GlcNAc) from UDP-GlcNAc to the C4 hydroxyl of a lipid-linked N-acetylmuramoyl pentapeptide...; Region: GT1_MurG; cd03785 663951007035 active site 663951007036 homodimer interface [polypeptide binding]; other site 663951007037 HMMPfam hit to PF04101, Glyco_tran_28_C, score 5.4e-23 663951007038 HMMPfam hit to PF03033, Glyco_transf_28, score 8.3e-37 663951007039 N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301 663951007040 Coenzyme A binding pocket [chemical binding]; other site 663951007041 HMMPfam hit to PF00583, Acetyltransf_1, score 8.1e-10 663951007042 Periplasmic protease [Cell envelope biogenesis, outer membrane]; Region: Prc; COG0793 663951007043 C-terminal processing peptidase family S41; Region: Peptidase_S41; cl02526 663951007044 PDZ domain of C-terminal processing-, tail-specific-, and tricorn proteases, which function in posttranslational protein processing, maturation, and disassembly or degradation, in Bacteria, Archaea, and plant chloroplasts. May be responsible for...; Region: PDZ_CTP_protease; cd00988 663951007045 protein binding site [polypeptide binding]; other site 663951007046 C-terminal processing peptidase; serine protease family S41; Region: Peptidase_S41_CPP; cd07560 663951007047 Catalytic dyad [active] 663951007048 Putative peptidoglycan binding domain; Region: PG_binding_1; pfam01471 663951007049 HMMPfam hit to PF01471, PG_binding_1, score 9.9e-14 663951007050 HMMPfam hit to PF03572, Peptidase_S41, score 1.3e-63 663951007051 HMMPfam hit to PF00595, PDZ, score 7.2e-16 663951007052 1 probable transmembrane helix predicted for SATW20_14210 by TMHMM2.0 at aa 39-61 663951007053 Protein of unknown function (DUF1250); Region: DUF1250; cl11485 663951007054 HMMPfam hit to PF06855, DUF1250, score 3.5e-33 663951007055 Phosphotransferase system IIA components [Carbohydrate transport and metabolism]; Region: NagE; COG2190 663951007056 HPr interaction site; other site 663951007057 glycerol kinase (GK) interaction site [polypeptide binding]; other site 663951007058 active site 663951007059 phosphorylation site [posttranslational modification] 663951007060 HMMPfam hit to PF00358, PTS_EIIA_1, score 2.4e-67 663951007061 PS00371 PTS EIIA domains phosphorylation site signature 1. 663951007062 methionine sulfoxide reductase B; Provisional; Region: PRK00222 663951007063 SelR domain; Region: SelR; pfam01641 663951007064 HMMPfam hit to PF01641, SelR, score 8.8e-72 663951007065 methionine sulfoxide reductase A; Provisional; Region: PRK13014 663951007066 HMMPfam hit to PF01625, PMSR, score 8e-76 663951007067 EDD domain protein, DegV family; Region: DegV; TIGR00762 663951007068 Uncharacterized protein, DegV family COG1307; Region: DegV; pfam02645 663951007069 HMMPfam hit to PF02645, DegV, score 3.7e-68 663951007070 Dihydrofolate reductase [Coenzyme metabolism]; Region: FolA; COG0262 663951007071 Dihydrofolate reductase (DHFR). Reduces 7,8-dihydrofolate to 5,6,7,8-tetrahydrofolate with NADPH as a cofactor. This is an essential step in the biosynthesis of deoxythymidine phosphate since 5,6,7,8-tetrahydrofolate is required to regenerate 5; Region: DHFR; cd00209 663951007072 folate binding site [chemical binding]; other site 663951007073 NADP+ binding site [chemical binding]; other site 663951007074 HMMPfam hit to PF00186, DHFR_1, score 6.8e-62 663951007075 PS00075 Dihydrofolate reductase signature. 663951007076 thymidylate synthase; Region: thym_sym; TIGR03284 663951007077 Thymidylate synthase and pyrimidine hydroxymethylase: Thymidylate synthase (TS) and deoxycytidylate hydroxymethylase (dCMP-HMase) are homologs that catalyze analogous alkylation of C5 of pyrimidine nucleotides. Both enzymes are involved in the...; Region: TS_Pyrimidine_HMase; cd00351 663951007078 dimerization interface [polypeptide binding]; other site 663951007079 active site 663951007080 HMMPfam hit to PF00303, Thymidylat_synt, score 1.1e-173 663951007081 PS00091 Thymidylate synthase active site. 663951007082 Disulphide isomerase; Region: Disulph_isomer; pfam06491 663951007083 HMMPfam hit to PF06491, DUF1094, score 1.9e-102 663951007084 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 663951007085 Scaffold protein Nfu/NifU N terminal; Region: Nfu_N; smart00932 663951007086 Virulence factor; Region: Virulence_fact; pfam13769 663951007087 HEAT repeats; Region: HEAT_2; pfam13646 663951007088 HEAT repeat; Region: HEAT; pfam02985 663951007089 HMMPfam hit to PF03130, HEAT_PBS, score 0.018 663951007090 HMMPfam hit to PF08712, Nfu_N, score 1.5e-05 663951007091 Scaffold protein Nfu/NifU N terminal; Region: Nfu_N; cl07364 663951007092 HMMPfam hit to PF08712, Nfu_N, score 6.7e-06 663951007093 Protein of unknown function (DUF2602); Region: DUF2602; pfam10782 663951007094 Uncharacterized member of the PurR regulon [General function prediction only]; Region: yhhQ; COG1738 663951007095 7 probable transmembrane helices predicted for SATW20_14330 by TMHMM2.0 at aa 5-22, 29-46, 51-73, 86-108,128-150, 170-192 and 196-218 663951007096 HMMPfam hit to PF02592, DUF165, score 6.5e-78 663951007097 RNAse HI family that includes Archaeal RNase HI; Region: RNase_HI_archaeal_like; cd09279 663951007098 RNA/DNA hybrid binding site [nucleotide binding]; other site 663951007099 active site 663951007100 YSIRK type signal peptide; Region: YSIRK_signal; pfam04650 663951007101 hyperosmolarity resistance protein Ebh, N-terminal domain; Region: hyperosmo_Ebh; TIGR04264 663951007102 GA module; Region: GA; smart00844 663951007103 GA module; Region: GA; smart00844 663951007104 GA module; Region: GA; smart00844 663951007105 GA module; Region: GA; smart00844 663951007106 GA module; Region: GA; smart00844 663951007107 GA module; Region: GA; smart00844 663951007108 GA module; Region: GA; smart00844 663951007109 GA module; Region: GA; smart00844 663951007110 GA module; Region: GA; smart00844 663951007111 GA module; Region: GA; smart00844 663951007112 GA module; Region: GA; smart00844 663951007113 GA module; Region: GA; smart00844 663951007114 GA module; Region: GA; smart00844 663951007115 GA module; Region: GA; smart00844 663951007116 GA module; Region: GA; smart00844 663951007117 GA module; Region: GA; smart00844 663951007118 GA module; Region: GA; smart00844 663951007119 GA module; Region: GA; smart00844 663951007120 GA module; Region: GA; smart00844 663951007121 GA module; Region: GA; pfam01468 663951007122 GA module; Region: GA; smart00844 663951007123 GA module; Region: GA; smart00844 663951007124 GA module; Region: GA; smart00844 663951007125 GA module; Region: GA; smart00844 663951007126 Uncharacterized Sugar-binding Domain; Region: FIVAR; pfam07554 663951007127 GA module; Region: GA; smart00844 663951007128 GA module; Region: GA; smart00844 663951007129 GA module; Region: GA; smart00844 663951007130 GA module; Region: GA; smart00844 663951007131 GA module; Region: GA; smart00844 663951007132 GA module; Region: GA; smart00844 663951007133 GA module; Region: GA; smart00844 663951007134 GA module; Region: GA; pfam01468 663951007135 GA module; Region: GA; smart00844 663951007136 GA module; Region: GA; smart00844 663951007137 GA module; Region: GA; smart00844 663951007138 GA module; Region: GA; smart00844 663951007139 GA module; Region: GA; smart00844 663951007140 GA module; Region: GA; smart00844 663951007141 GA module; Region: GA; smart00844 663951007142 ATPase involved in DNA repair [DNA replication, recombination, and repair]; Region: SbcC; COG0419 663951007143 GA module; Region: GA; smart00844 663951007144 GA module; Region: GA; smart00844 663951007145 GA module; Region: GA; smart00844 663951007146 GA module; Region: GA; smart00844 663951007147 Domain of Unknown Function (DUF1542); Region: DUF1542; pfam07564 663951007148 Domain of Unknown Function (DUF1542); Region: DUF1542; pfam07564 663951007149 1 probable transmembrane helix predicted for SATW20_14350 by TMHMM2.0 at aa 10226-10248 663951007150 HMMPfam hit to PF07564, DUF1542, score 1.4e-18 663951007151 HMMPfam hit to PF07564, DUF1542, score 7.3e-15 663951007152 HMMPfam hit to PF07564, DUF1542, score 5e-15 663951007153 HMMPfam hit to PF07564, DUF1542, score 3.7e-19 663951007154 HMMPfam hit to PF07564, DUF1542, score 6.9e-16 663951007155 HMMPfam hit to PF07564, DUF1542, score 3.4e-13 663951007156 HMMPfam hit to PF07564, DUF1542, score 1.6e-12 663951007157 HMMPfam hit to PF01468, GA, score 1e-05 663951007158 HMMPfam hit to PF07554, FIVAR, score 4.9e-09 663951007159 HMMPfam hit to PF01468, GA, score 4.7e-14 663951007160 HMMPfam hit to PF01468, GA, score 3.3e-14 663951007161 HMMPfam hit to PF07554, FIVAR, score 1e-06 663951007162 HMMPfam hit to PF01468, GA, score 2e-15 663951007163 HMMPfam hit to PF07554, FIVAR, score 8.9e-09 663951007164 HMMPfam hit to PF01468, GA, score 3.2e-14 663951007165 HMMPfam hit to PF07554, FIVAR, score 2.7e-08 663951007166 HMMPfam hit to PF01468, GA, score 3.2e-17 663951007167 HMMPfam hit to PF07554, FIVAR, score 1.1e-07 663951007168 HMMPfam hit to PF01468, GA, score 1.2e-19 663951007169 HMMPfam hit to PF07554, FIVAR, score 2.6e-08 663951007170 HMMPfam hit to PF01468, GA, score 2.9e-15 663951007171 HMMPfam hit to PF07554, FIVAR, score 1.5e-06 663951007172 HMMPfam hit to PF01468, GA, score 7e-16 663951007173 HMMPfam hit to PF07554, FIVAR, score 7.1e-07 663951007174 HMMPfam hit to PF01468, GA, score 2.2e-15 663951007175 HMMPfam hit to PF07554, FIVAR, score 2.3e-06 663951007176 HMMPfam hit to PF01468, GA, score 6.8e-14 663951007177 HMMPfam hit to PF07554, FIVAR, score 2.1e-06 663951007178 HMMPfam hit to PF01468, GA, score 1.3e-15 663951007179 HMMPfam hit to PF07554, FIVAR, score 4.3e-07 663951007180 HMMPfam hit to PF01468, GA, score 3.9e-17 663951007181 HMMPfam hit to PF07554, FIVAR, score 5.1e-07 663951007182 HMMPfam hit to PF01468, GA, score 5.6e-16 663951007183 HMMPfam hit to PF07554, FIVAR, score 3.3e-06 663951007184 HMMPfam hit to PF01468, GA, score 5.9e-18 663951007185 HMMPfam hit to PF07554, FIVAR, score 6.7e-07 663951007186 HMMPfam hit to PF01468, GA, score 1.5e-17 663951007187 HMMPfam hit to PF07554, FIVAR, score 2.1e-09 663951007188 HMMPfam hit to PF01468, GA, score 2.5e-16 663951007189 HMMPfam hit to PF07554, FIVAR, score 8.5e-09 663951007190 HMMPfam hit to PF01468, GA, score 1.6e-14 663951007191 HMMPfam hit to PF07554, FIVAR, score 2.9e-07 663951007192 HMMPfam hit to PF01468, GA, score 9.9e-17 663951007193 HMMPfam hit to PF07554, FIVAR, score 1.1e-09 663951007194 HMMPfam hit to PF01468, GA, score 1.3e-14 663951007195 HMMPfam hit to PF07554, FIVAR, score 1.5e-09 663951007196 HMMPfam hit to PF01468, GA, score 6.6e-16 663951007197 HMMPfam hit to PF07554, FIVAR, score 1.4e-09 663951007198 HMMPfam hit to PF01468, GA, score 5.2e-14 663951007199 HMMPfam hit to PF07554, FIVAR, score 1.1e-07 663951007200 HMMPfam hit to PF01468, GA, score 3.9e-12 663951007201 HMMPfam hit to PF07554, FIVAR, score 7.8e-08 663951007202 HMMPfam hit to PF01468, GA, score 2.1e-20 663951007203 HMMPfam hit to PF07554, FIVAR, score 1.1e-07 663951007204 HMMPfam hit to PF01468, GA, score 8.1e-22 663951007205 HMMPfam hit to PF07554, FIVAR, score 1e-05 663951007206 HMMPfam hit to PF01468, GA, score 3.3e-18 663951007207 HMMPfam hit to PF07554, FIVAR, score 1.7e-09 663951007208 HMMPfam hit to PF01468, GA, score 1.8e-17 663951007209 HMMPfam hit to PF07554, FIVAR, score 5.3e-07 663951007210 HMMPfam hit to PF01468, GA, score 1.6e-14 663951007211 HMMPfam hit to PF07554, FIVAR, score 5.2e-08 663951007212 HMMPfam hit to PF01468, GA, score 7.4e-18 663951007213 HMMPfam hit to PF07554, FIVAR, score 1.8e-05 663951007214 HMMPfam hit to PF01468, GA, score 1.5e-17 663951007215 HMMPfam hit to PF07554, FIVAR, score 4.3e-07 663951007216 HMMPfam hit to PF01468, GA, score 7.1e-17 663951007217 HMMPfam hit to PF07554, FIVAR, score 1.3e-08 663951007218 HMMPfam hit to PF01468, GA, score 4.7e-16 663951007219 HMMPfam hit to PF07554, FIVAR, score 5.4e-08 663951007220 HMMPfam hit to PF01468, GA, score 2.9e-14 663951007221 HMMPfam hit to PF07554, FIVAR, score 6.4e-08 663951007222 HMMPfam hit to PF01468, GA, score 1e-16 663951007223 HMMPfam hit to PF07554, FIVAR, score 1.9e-07 663951007224 HMMPfam hit to PF01468, GA, score 2.3e-16 663951007225 HMMPfam hit to PF07554, FIVAR, score 2.7e-08 663951007226 HMMPfam hit to PF01468, GA, score 9e-17 663951007227 HMMPfam hit to PF07554, FIVAR, score 4e-08 663951007228 HMMPfam hit to PF01468, GA, score 6.6e-16 663951007229 HMMPfam hit to PF07554, FIVAR, score 2.2e-07 663951007230 HMMPfam hit to PF01468, GA, score 2.1e-16 663951007231 HMMPfam hit to PF07554, FIVAR, score 2.1e-09 663951007232 HMMPfam hit to PF01468, GA, score 2.9e-16 663951007233 HMMPfam hit to PF07554, FIVAR, score 5.6e-07 663951007234 HMMPfam hit to PF01468, GA, score 3.1e-14 663951007235 HMMPfam hit to PF07554, FIVAR, score 5.9e-07 663951007236 HMMPfam hit to PF01468, GA, score 1.6e-15 663951007237 HMMPfam hit to PF07554, FIVAR, score 1.9e-06 663951007238 HMMPfam hit to PF01468, GA, score 3.8e-14 663951007239 HMMPfam hit to PF07554, FIVAR, score 1.2e-06 663951007240 HMMPfam hit to PF01468, GA, score 2.9e-14 663951007241 HMMPfam hit to PF07554, FIVAR, score 9.2e-09 663951007242 HMMPfam hit to PF01468, GA, score 1.9e-17 663951007243 HMMPfam hit to PF07554, FIVAR, score 8.2e-07 663951007244 HMMPfam hit to PF01468, GA, score 4.8e-14 663951007245 HMMPfam hit to PF07554, FIVAR, score 2.9e-07 663951007246 HMMPfam hit to PF01468, GA, score 3.4e-14 663951007247 HMMPfam hit to PF07554, FIVAR, score 1e-09 663951007248 HMMPfam hit to PF01468, GA, score 5e-17 663951007249 HMMPfam hit to PF07554, FIVAR, score 1.8e-07 663951007250 HMMPfam hit to PF01468, GA, score 9.9e-19 663951007251 HMMPfam hit to PF07554, FIVAR, score 3.9e-09 663951007252 HMMPfam hit to PF01468, GA, score 5.3e-14 663951007253 HMMPfam hit to PF07554, FIVAR, score 9.4e-10 663951007254 HMMPfam hit to PF01468, GA, score 2.8e-16 663951007255 HMMPfam hit to PF07554, FIVAR, score 2.8e-08 663951007256 HMMPfam hit to PF01468, GA, score 9.4e-16 663951007257 HMMPfam hit to PF07554, FIVAR, score 1.6e-10 663951007258 HMMPfam hit to PF01468, GA, score 2.2e-15 663951007259 HMMPfam hit to PF07554, FIVAR, score 4.1e-06 663951007260 HMMPfam hit to PF07554, FIVAR, score 1.6e-08 663951007261 HMMPfam hit to PF07554, FIVAR, score 4.6e-07 663951007262 HMMPfam hit to PF07554, FIVAR, score 8.9e-07 663951007263 HMMPfam hit to PF07554, FIVAR, score 7.7e-07 663951007264 HMMPfam hit to PF07554, FIVAR, score 5.3e-07 663951007265 HMMPfam hit to PF07554, FIVAR, score 4.1e-10 663951007266 HMMPfam hit to PF04650, YSIRK_signal, score 1.4e-10 663951007267 drug resistance transporter, EmrB/QacA subfamily; Region: efflux_EmrB; TIGR00711 663951007268 14 probable transmembrane helices predicted for SATW20_14360 by TMHMM2.0 at aa 13-35, 50-72, 85-107,111-133, 140-162, 166-185, 206-223, 228-250, 271-293,303-322, 334-353, 357-379, 400-422 and 432-454 663951007269 HMMPfam hit to PF07690, MFS_1, score 5.9e-43 663951007270 Amino acid permease; Region: AA_permease_2; pfam13520 663951007271 HMMPfam hit to PF00324, AA_permease, score 5.7e-31 663951007272 12 probable transmembrane helices predicted for SATW20_14370 by TMHMM2.0 at aa 12-34, 49-71, 91-113,123-145, 152-174, 194-216, 229-251, 282-299, 327-349,353-375, 388-407 and 411-433 663951007273 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 663951007274 PS00095 C-5 cytosine-specific DNA methylases C-terminal signature. 663951007275 Threonine dehydratase [Amino acid transport and metabolism]; Region: IlvA; COG1171 663951007276 Threonine dehydratase: The first step in amino acid degradation is the removal of nitrogen. Although the nitrogen atoms of most amino acids are transferred to alpha-ketoglutarate before removal, the alpha-amino group of threonine can be directly...; Region: Thr-dehyd; cd01562 663951007277 tetramer interface [polypeptide binding]; other site 663951007278 pyridoxal 5'-phosphate binding site [chemical binding]; other site 663951007279 catalytic residue [active] 663951007280 HMMPfam hit to PF00291, PALP, score 1.7e-86 663951007281 PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 663951007282 Alanine dehydrogenase [Amino acid transport and metabolism]; Region: Ald; COG0686 663951007283 Alanine dehydrogenase NAD-binding and catalytic domains; Region: L-AlaDH; cd05305 663951007284 hexamer interface [polypeptide binding]; other site 663951007285 ligand binding site [chemical binding]; other site 663951007286 putative active site [active] 663951007287 NAD(P) binding site [chemical binding]; other site 663951007288 HMMPfam hit to PF01262, AlaDh_PNT_C, score 1.3e-69 663951007289 HMMPfam hit to PF05222, AlaDh_PNT_N, score 1.7e-67 663951007290 5'-3' exonuclease; Region: 53EXOc; smart00475 663951007291 PIN domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: PIN_53EXO; cd09859 663951007292 active site 663951007293 metal binding site 1 [ion binding]; metal-binding site 663951007294 putative 5' ssDNA interaction site; other site 663951007295 metal binding site 3; metal-binding site 663951007296 metal binding site 2 [ion binding]; metal-binding site 663951007297 H3TH domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: H3TH_53EXO; cd09898 663951007298 putative DNA binding site [nucleotide binding]; other site 663951007299 putative metal binding site [ion binding]; other site 663951007300 HMMPfam hit to PF01367, 5_3_exonuc, score 1.1e-38 663951007301 HMMPfam hit to PF02739, 5_3_exonuc_N, score 4.9e-72 663951007302 Dynamin-like protein including dynamins, mitofusins, and guanylate-binding proteins; Region: DLP_2; cd09912 663951007303 Dynamin family; Region: Dynamin_N; pfam00350 663951007304 G1 box; other site 663951007305 GTP/Mg2+ binding site [chemical binding]; other site 663951007306 G2 box; other site 663951007307 Switch I region; other site 663951007308 G3 box; other site 663951007309 Switch II region; other site 663951007310 G4 box; other site 663951007311 Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cl17170 663951007312 Dynamin family; Region: Dynamin_N; pfam00350 663951007313 G1 box; other site 663951007314 GTP/Mg2+ binding site [chemical binding]; other site 663951007315 G2 box; other site 663951007316 Switch I region; other site 663951007317 Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cl17170 663951007318 G3 box; other site 663951007319 Switch II region; other site 663951007320 GTP/Mg2+ binding site [chemical binding]; other site 663951007321 G4 box; other site 663951007322 G5 box; other site 663951007323 HMMPfam hit to PF00350, Dynamin_N, score 1.7e-47 663951007324 PS00017 ATP/GTP-binding site motif A (P-loop). 663951007325 HMMPfam hit to PF00350, Dynamin_N, score 1.1e-44 663951007326 PS00017 ATP/GTP-binding site motif A (P-loop). 663951007327 Uncharacterized iron-regulated membrane protein [Function unknown]; Region: PiuB; COG3182 663951007328 PepSY-associated TM helix; Region: PepSY_TM_1; pfam13172 663951007329 PepSY-associated TM helix; Region: PepSY_TM_2; pfam13703 663951007330 HMMPfam hit to PF03929, PepSY_TM, score 0.048 663951007331 5 probable transmembrane helices predicted for SATW20_14420 by TMHMM2.0 at aa 15-37, 139-161, 181-203,366-387 and 407-438 663951007332 HMMPfam hit to PF03929, PepSY_TM, score 0.015 663951007333 HMMPfam hit to PF03929, PepSY_TM, score 0.069 663951007334 HMMPfam hit to PF03413, PepSY, score 6.4e-05 663951007335 HMMPfam hit to PF03929, PepSY_TM, score 0.088 663951007336 Cobalt transport protein component CbiN; Region: CbiN; cl00842 663951007337 1 probable transmembrane helix predicted for SATW20_14430 by TMHMM2.0 at aa 5-27 663951007338 Predicted N6-adenine-specific DNA methylase [DNA replication, recombination, and repair]; Region: COG0116 663951007339 THUMP domain associated with S-adenosylmethionine-dependent methyltransferases; Region: THUMP_AdoMetMT; cd11715 663951007340 S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173 663951007341 HMMPfam hit to PF01170, UPF0020, score 5.2e-67 663951007342 PS00092 N-6 Adenine-specific DNA methylases signature. 663951007343 PS01261 Uncharacterized protein family UPF0020 signature. 663951007344 cell division protein GpsB; Provisional; Region: PRK14127 663951007345 DivIVA domain; Region: DivI1A_domain; TIGR03544 663951007346 HMMPfam hit to PF05103, DivIVA, score 6.4e-09 663951007347 hypothetical protein; Provisional; Region: PRK13660 663951007348 HMMPfam hit to PF06908, DUF1273, score 4.1e-123 663951007349 Bacterial domain of unknown function (DUF1798); Region: DUF1798; pfam08807 663951007350 HMMPfam hit to PF08807, DUF1798, score 8.5e-51 663951007351 Holliday junction-specific endonuclease; Reviewed; Region: recU; PRK02234 663951007352 HMMPfam hit to PF03838, RecU, score 5.3e-119 663951007353 Membrane carboxypeptidase (penicillin-binding protein) [Cell envelope biogenesis, outer membrane]; Region: MrcB; COG0744 663951007354 Transglycosylase; Region: Transgly; pfam00912 663951007355 Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760 663951007356 1 probable transmembrane helix predicted for SATW20_14490 by TMHMM2.0 at aa 35-57 663951007357 HMMPfam hit to PF00912, Transgly, score 3.8e-80 663951007358 HMMPfam hit to PF00905, Transpeptidase, score 3.1e-23 663951007359 Predicted EndoIII-related endonuclease [DNA replication, recombination, and repair]; Region: Nth; COG0177 663951007360 endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056 663951007361 minor groove reading motif; other site 663951007362 helix-hairpin-helix signature motif; other site 663951007363 substrate binding pocket [chemical binding]; other site 663951007364 active site 663951007365 Iron-sulfur binding domain of endonuclease III; Region: EndIII_4Fe-2S; pfam10576 663951007366 PS00764 Endonuclease III iron-sulfur binding region signature. 663951007367 HMMPfam hit to PF00730, HhH-GPD, score 5.9e-22 663951007368 HMMPfam hit to PF00633, HHH, score 1.9e-07 663951007369 Putative primosome component and related proteins [DNA replication, recombination, and repair]; Region: DnaD; COG3935 663951007370 Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4950; cl17731 663951007371 Replication initiation and membrane attachment; Region: DnaB_2; pfam07261 663951007372 HMMPfam hit to PF04271, DnaD, score 3.1e-37 663951007373 asparaginyl-tRNA synthetase; Validated; Region: asnC; PRK03932 663951007374 AsnRS_cyto_like_N: N-terminal, anticodon recognition domain of the type found in human and Saccharomyces cerevisiae cytoplasmic asparaginyl-tRNA synthetase (AsnRS), in Brugia malayai AsnRs and, in various putative bacterial AsnRSs. This domain is a...; Region: AsnRS_cyto_like_N; cd04323 663951007375 putative dimer interface [polypeptide binding]; other site 663951007376 putative anticodon binding site; other site 663951007377 Asx tRNA synthetase (AspRS/AsnRS) class II core domain. Assignment to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure and the presence of three characteristic sequence motifs in the core domain. This family includes AsnRS as well as...; Region: AsxRS_core; cd00776 663951007378 homodimer interface [polypeptide binding]; other site 663951007379 motif 1; other site 663951007380 motif 2; other site 663951007381 active site 663951007382 motif 3; other site 663951007383 HMMPfam hit to PF00152, tRNA-synt_2, score 5.5e-109 663951007384 PS00179 Aminoacyl-transfer RNA synthetases class-II signature 1. 663951007385 HMMPfam hit to PF01336, tRNA_anti, score 1.3e-21 663951007386 DnaQ family exonuclease/DinG family helicase, putative; Region: dinG_rel; TIGR01407 663951007387 DEDDh 3'-5' exonuclease domain family; Region: DEDDh; cd06127 663951007388 active site 663951007389 catalytic site [active] 663951007390 substrate binding site [chemical binding]; other site 663951007391 CRISPR/Cas system-associated DinG family helicase Csf4; Region: Csf4_U; cl17460 663951007392 Helicase C-terminal domain; Region: Helicase_C_2; pfam13307 663951007393 PS00017 ATP/GTP-binding site motif A (P-loop). 663951007394 HMMPfam hit to PF00929, Exonuc_X-T, score 4.3e-28 663951007395 Biotin operon repressor [Transcription]; Region: BirA; COG1654 663951007396 Biotin-(acetyl-CoA carboxylase) ligase [Coenzyme metabolism]; Region: BirA; COG0340 663951007397 Biotin/lipoate A/B protein ligase family; Region: BPL_LplA_LipB; cl14057 663951007398 HMMPfam hit to PF03099, BPL_LipA_LipB, score 1.7e-15 663951007399 HMMPfam hit to PF08279, HTH_11, score 4.7e-16 663951007400 Predicted helix-turn-helix motif with score 1321.000, SD 3.69 at aa 20-41, sequence ISGQSIAESLNISRTAVKKVID 663951007401 tRNA CCA-pyrophosphorylase; Provisional; Region: PRK13299 663951007402 Nucleotidyltransferase (NT) domain of ClassII CCA-adding enzymes; Region: NT_ClassII-CCAase; cd05398 663951007403 active site 663951007404 NTP binding site [chemical binding]; other site 663951007405 metal binding triad [ion binding]; metal-binding site 663951007406 Probable RNA and SrmB- binding site of polymerase A; Region: PolyA_pol_RNAbd; pfam12627 663951007407 tRNA nucleotidyltransferase domain 2 putative; Region: tRNA_NucTran2_2; pfam13735 663951007408 HMMPfam hit to PF01743, PolyA_pol, score 8.7e-53 663951007409 N-acetyl-alpha-D-glucosaminyl L-malate synthase BshA; Region: thiol_BshA; TIGR03999 663951007410 This family is most closely related to the GT1 family of glycosyltransferases. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can...; Region: GT1_like_5; cd04962 663951007411 HMMPfam hit to PF00534, Glycos_transf_1, score 4.7e-40 663951007412 Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) MazG-like domain putative pyrophosphatase YpjD from Bacillus subtilis and its bacterial homologs; Region: NTP-PPase_BsYpjD; cd11531 663951007413 homodimer interface [polypeptide binding]; other site 663951007414 metal binding site [ion binding]; metal-binding site 663951007415 HMMPfam hit to PF03819, MazG, score 2.2e-29 663951007416 Predicted Zn-dependent protease [General function prediction only]; Region: COG2738 663951007417 HMMPfam hit to PF04298, Zn_peptidase_2, score 3.1e-172 663951007418 4 probable transmembrane helices predicted for SATW20_14590 by TMHMM2.0 at aa 4-21, 119-141, 151-173 and 202-224 663951007419 PS00107 Protein kinases ATP-binding region signature. 663951007420 PS00142 Neutral zinc metallopeptidases, zinc-binding region signature. 663951007421 Predicted membrane protein [Function unknown]; Region: COG4347 663951007422 HMMPfam hit to PF07187, DUF1405, score 1.5e-133 663951007423 6 probable transmembrane helices predicted for SATW20_14600 by TMHMM2.0 at aa 13-35, 50-69, 78-100,105-127, 134-156 and 166-188 663951007424 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 663951007425 Uncharacterized conserved protein [Function unknown]; Region: COG5582 663951007426 UPF0302 domain; Region: UPF0302; pfam08864 663951007427 A short protein domain of unknown function; Region: IDEAL; smart00914 663951007428 HMMPfam hit to PF08858, IDEAL, score 6.1e-10 663951007429 HMMPfam hit to PF08864, UPF0302, score 5.6e-55 663951007430 TPR repeat; Region: TPR_11; pfam13414 663951007431 Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189 663951007432 binding surface 663951007433 TPR motif; other site 663951007434 Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189 663951007435 TPR motif; other site 663951007436 binding surface 663951007437 HMMPfam hit to PF07719, TPR_2, score 0.0011 663951007438 3-phosphoshikimate 1-carboxyvinyltransferase; Provisional; Region: PRK02427 663951007439 EPSP synthase domain. 3-phosphoshikimate 1-carboxyvinyltransferase (5-enolpyruvylshikimate-3-phosphate synthase) (EC 2.5.1.19) catalyses the reaction between shikimate-3-phosphate (S3P) and phosphoenolpyruvate (PEP) to form...; Region: EPSP_synthase; cd01556 663951007440 hinge; other site 663951007441 active site 663951007442 HMMPfam hit to PF00275, EPSP_synthase, score 6.8e-185 663951007443 PS00104 EPSP synthase signature 1. 663951007444 Dehydroquinate synthase-like (DHQ-like) and iron-containing alcohol dehydrogenases (Fe-ADH); Region: DHQ_Fe-ADH; cl02872 663951007445 active site 663951007446 NAD binding site [chemical binding]; other site 663951007447 metal binding site [ion binding]; metal-binding site 663951007448 HMMPfam hit to PF01761, DHQ_synthase, score 2.6e-121 663951007449 Chorismate synthase [Amino acid transport and metabolism]; Region: AroC; COG0082 663951007450 Chorismase synthase, the enzyme catalyzing the final step of the shikimate pathway; Region: Chorismate_synthase; cd07304 663951007451 Tetramer interface [polypeptide binding]; other site 663951007452 active site 663951007453 FMN-binding site [chemical binding]; other site 663951007454 HMMPfam hit to PF01264, Chorismate_synt, score 5.4e-228 663951007455 PS00789 Chorismate synthase signature 3. 663951007456 PS00788 Chorismate synthase signature 2. 663951007457 PS00787 Chorismate synthase signature 1. 663951007458 Nucleoside diphosphate kinase Group I (NDPk_I)-like: NDP kinase domains are present in a large family of structurally and functionally conserved proteins from bacteria to humans that generally catalyze the transfer of gamma-phosphates of a nucleoside...; Region: NDPk_I; cd04413 663951007459 active site 663951007460 multimer interface [polypeptide binding]; other site 663951007461 HMMPfam hit to PF00334, NDK, score 4.8e-89 663951007462 PS00469 Nucleoside diphosphate kinases active site. 663951007463 Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; Region: IspA; COG0142 663951007464 Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685 663951007465 substrate binding pocket [chemical binding]; other site 663951007466 chain length determination region; other site 663951007467 substrate-Mg2+ binding site; other site 663951007468 catalytic residues [active] 663951007469 aspartate-rich region 1; other site 663951007470 active site lid residues [active] 663951007471 aspartate-rich region 2; other site 663951007472 HMMPfam hit to PF00348, polyprenyl_synt, score 2.2e-76 663951007473 PS00444 Polyprenyl synthetases signature 2. 663951007474 PS00723 Polyprenyl synthetases signature 1. 663951007475 Methylase involved in ubiquinone/menaquinone biosynthesis [Coenzyme metabolism]; Region: UbiE; COG2226 663951007476 S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440 663951007477 S-adenosylmethionine binding site [chemical binding]; other site 663951007478 HMMPfam hit to PF01209, Ubie_methyltran, score 1.4e-127 663951007479 PS01184 ubiE/COQ5 methyltransferase family signature 2. 663951007480 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1; Region: HEPPP_synt_1; pfam07307 663951007481 Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591 663951007482 IHF dimer interface [polypeptide binding]; other site 663951007483 IHF - DNA interface [nucleotide binding]; other site 663951007484 HMMPfam hit to PF00216, Bac_DNA_binding, score 1.7e-55 663951007485 PS00045 Bacterial histone-like DNA-binding proteins signature. 663951007486 NAD(P)H-dependent glycerol-3-phosphate dehydrogenase; Validated; Region: gpsA; PRK00094 663951007487 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; Region: NAD_Gly3P_dh_N; pfam01210 663951007488 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus; Region: NAD_Gly3P_dh_C; pfam07479 663951007489 HMMPfam hit to PF07479, NAD_Gly3P_dh_C, score 1.9e-76 663951007490 HMMPfam hit to PF01210, NAD_Gly3P_dh_N, score 9.1e-64 663951007491 GTP-binding protein Der; Reviewed; Region: PRK00093 663951007492 EngA1 GTPase contains the first domain of EngA; Region: EngA1; cd01894 663951007493 G1 box; other site 663951007494 GTP/Mg2+ binding site [chemical binding]; other site 663951007495 Switch I region; other site 663951007496 G2 box; other site 663951007497 Switch II region; other site 663951007498 G3 box; other site 663951007499 G4 box; other site 663951007500 G5 box; other site 663951007501 EngA2 GTPase contains the second domain of EngA; Region: EngA2; cd01895 663951007502 G1 box; other site 663951007503 GTP/Mg2+ binding site [chemical binding]; other site 663951007504 Switch I region; other site 663951007505 G2 box; other site 663951007506 G3 box; other site 663951007507 Switch II region; other site 663951007508 G4 box; other site 663951007509 G5 box; other site 663951007510 HMMPfam hit to PF01926, MMR_HSR1, score 6.6e-46 663951007511 PS00017 ATP/GTP-binding site motif A (P-loop). 663951007512 HMMPfam hit to PF01926, MMR_HSR1, score 3.2e-45 663951007513 PS00017 ATP/GTP-binding site motif A (P-loop). 663951007514 30S ribosomal protein S1; Reviewed; Region: rpsA; PRK06676 663951007515 S1_RPS1_repeat_ec1_hs1: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture...; Region: S1_RPS1_repeat_ec1_hs1; cd05687 663951007516 RNA binding site [nucleotide binding]; other site 663951007517 S1_RPS1_repeat_ec2_hs2: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture...; Region: S1_RPS1_repeat_ec2_hs2; cd04465 663951007518 RNA binding site [nucleotide binding]; other site 663951007519 S1_RPS1_repeat_ec3: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec3; cd05688 663951007520 RNA binding site [nucleotide binding]; other site 663951007521 S1_RPS1_repeat_hs4: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_hs4; cd05692 663951007522 RNA binding site [nucleotide binding]; other site 663951007523 HMMPfam hit to PF00575, S1, score 2.9e-26 663951007524 HMMPfam hit to PF00575, S1, score 4.3e-29 663951007525 HMMPfam hit to PF00575, S1, score 1.4e-16 663951007526 HMMPfam hit to PF00575, S1, score 1.8e-14 663951007527 cytidylate kinase; Provisional; Region: cmk; PRK00023 663951007528 Cytidine monophosphate kinase (CMPK) catalyzes the reversible phosphorylation of cytidine monophosphate (CMP) to produce cytidine diphosphate (CDP), using ATP as the preferred phosphoryl donor; Region: CMPK; cd02020 663951007529 CMP-binding site; other site 663951007530 The sites determining sugar specificity; other site 663951007531 HMMPfam hit to PF02224, Cytidylate_kin, score 4.3e-66 663951007532 PS00017 ATP/GTP-binding site motif A (P-loop). 663951007533 Type II (periplasmic) bacterial L-asparaginase; Region: L-asparaginase_II; cd08964 663951007534 active site 663951007535 homotetramer interface [polypeptide binding]; other site 663951007536 homodimer interface [polypeptide binding]; other site 663951007537 HMMPfam hit to PF00710, Asparaginase, score 4.8e-146 663951007538 PS00144 Asparaginase / glutaminase active site signature 1. 663951007539 PS00917 Asparaginase / glutaminase active site signature 2. 663951007540 putative bacillithiol system oxidoreductase, YpdA family; Region: Bthiol_YpdA; TIGR04018 663951007541 Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox_3; pfam13738 663951007542 Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070 663951007543 HMMPfam hit to PF00070, Pyr_redox, score 0.00051 663951007544 HMMPfam hit to PF01494, FAD_binding_3, score 8.5e-09 663951007545 Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118 663951007546 HMMPfam hit to PF01476, LysM, score 1.7e-06 663951007547 1 probable transmembrane helix predicted for SATW20_14780 by TMHMM2.0 at aa 320-342 663951007548 Superfamily II DNA helicase [DNA replication, recombination, and repair]; Region: RecQ; COG0514 663951007549 DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046 663951007550 ATP binding site [chemical binding]; other site 663951007551 putative Mg++ binding site [ion binding]; other site 663951007552 Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079 663951007553 nucleotide binding region [chemical binding]; other site 663951007554 ATP-binding site [chemical binding]; other site 663951007555 HMMPfam hit to PF00271, Helicase_C, score 9.4e-28 663951007556 HMMPfam hit to PF00270, DEAD, score 8.2e-28 663951007557 PS00690 DEAH-box subfamily ATP-dependent helicases signature. 663951007558 Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4955 663951007559 Ferredoxin [Energy production and conversion]; Region: Fer; COG1141 663951007560 Predicted membrane protein [Function unknown]; Region: COG3601 663951007561 Protein of unknown function (DUF3816); Region: DUF3816; pfam12822 663951007562 5 probable transmembrane helices predicted for SATW20_14820 by TMHMM2.0 at aa 7-29, 44-66, 78-95, 105-127 and 147-169 663951007563 Protein of unknown function (DUF1672); Region: DUF1672; pfam07901 663951007564 HMMPfam hit to PF07901, DUF1672, score 2.3e-200 663951007565 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 663951007566 Protein of unknown function (DUF1672); Region: DUF1672; pfam07901 663951007567 HMMPfam hit to PF07901, DUF1672, score 8.8e-204 663951007568 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 663951007569 Protein of unknown function (DUF1672); Region: DUF1672; pfam07901 663951007570 HMMPfam hit to PF07901, DUF1672, score 1e-231 663951007571 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 663951007572 Predicted helix-turn-helix motif with score 980.000,SD 2.52 at aa 390-411, sequence NSLEEVADETIESISAVKHLLP 663951007573 Protein of unknown function (DUF1672); Region: DUF1672; pfam07901 663951007574 HMMPfam hit to PF07901, DUF1672, score 7e-205 663951007575 Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225 663951007576 dimerization interface [polypeptide binding]; other site 663951007577 phosphate regulon sensor kinase PhoR; Region: phoR_proteo; TIGR02966 663951007578 Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082 663951007579 dimer interface [polypeptide binding]; other site 663951007580 phosphorylation site [posttranslational modification] 663951007581 Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075 663951007582 ATP binding site [chemical binding]; other site 663951007583 Mg2+ binding site [ion binding]; other site 663951007584 G-X-G motif; other site 663951007585 HMMPfam hit to PF02518, HATPase_c, score 2.5e-41 663951007586 HMMPfam hit to PF00512, HisKA, score 4.3e-21 663951007587 HMMPfam hit to PF00672, HAMP, score 4.9e-22 663951007588 2 probable transmembrane helices predicted for SATW20_14890 by TMHMM2.0 at aa 4-21 and 154-176 663951007589 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745 663951007590 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 663951007591 active site 663951007592 phosphorylation site [posttranslational modification] 663951007593 intermolecular recognition site; other site 663951007594 dimerization interface [polypeptide binding]; other site 663951007595 Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383 663951007596 DNA binding site [nucleotide binding] 663951007597 HMMPfam hit to PF00486, Trans_reg_C, score 5.2e-24 663951007598 HMMPfam hit to PF00072, Response_reg, score 5.2e-42 663951007599 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases [Translation, ribosomal structure and biogenesis]; Region: RsuA; COG1187 663951007600 S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site; Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165 663951007601 RNA binding surface [nucleotide binding]; other site 663951007602 Pseudouridine synthases, RsuA subfamily; Region: PseudoU_synth_RsuA_like; cd02870 663951007603 active site 663951007604 HMMPfam hit to PF00849, PseudoU_synth_2, score 3.6e-22 663951007605 PS01149 Rsu family of pseudouridine synthase signature. 663951007606 HMMPfam hit to PF01479, S4, score 5.8e-14 663951007607 Chromosome segregation and condensation protein B [DNA replication, recombination and repair]; Region: scpB; COG1386 663951007608 HMMPfam hit to PF04079, DUF387, score 1.4e-65 663951007609 segregation and condensation protein A; Reviewed; Region: scpA; PRK00104 663951007610 HMMPfam hit to PF02616, ScpA_ScpB, score 7.9e-31 663951007611 Predicted metal-dependent hydrolase [General function prediction only]; Region: COG1547 663951007612 HMMPfam hit to PF03745, DUF309, score 8.7e-07 663951007613 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 663951007614 Site-specific recombinase XerD [DNA replication, recombination, and repair]; Region: XerD; COG4974 663951007615 XerD and XerC integrases, DNA breaking-rejoining enzymes, N- and C-terminal domains. XerD-like integrases are involved in the site-specific integration and excision of lysogenic bacteriophage genomes, transposition of conjugative transposons, termination...; Region: INT_XerDC; cd00798 663951007616 active site 663951007617 Int/Topo IB signature motif; other site 663951007618 HMMPfam hit to PF00589, Phage_integrase, score 2.1e-62 663951007619 HMMPfam hit to PF02899, Phage_integr_N, score 4.6e-34 663951007620 Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators; Region: Fur_like; cd07153 663951007621 metal binding site 2 [ion binding]; metal-binding site 663951007622 putative DNA binding helix; other site 663951007623 metal binding site 1 [ion binding]; metal-binding site 663951007624 dimer interface [polypeptide binding]; other site 663951007625 structural Zn2+ binding site [ion binding]; other site 663951007626 HMMPfam hit to PF01475, FUR, score 3.5e-52 663951007627 ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+; Region: ADPRase_NUDT5; cd03424 663951007628 dimer interface [polypeptide binding]; other site 663951007629 ADP-ribose binding site [chemical binding]; other site 663951007630 active site 663951007631 nudix motif; other site 663951007632 metal binding site [ion binding]; metal-binding site 663951007633 HMMPfam hit to PF00293, NUDIX, score 2.5e-25 663951007634 PS00893 mutT domain signature. 663951007635 Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660 663951007636 Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248 663951007637 active site 663951007638 catalytic tetrad [active] 663951007639 HMMPfam hit to PF00248, Aldo_ket_red, score 9e-16 663951007640 Short-chain dehydrogenases of various substrate specificities [General function prediction only]; Region: DltE; COG0300 663951007641 classical (c) SDRs; Region: SDR_c; cd05233 663951007642 NAD(P) binding site [chemical binding]; other site 663951007643 active site 663951007644 HMMPfam hit to PF00106, adh_short, score 1.9e-07 663951007645 NADP oxidoreductase coenzyme F420-dependent; Region: F420_oxidored; cl17232 663951007646 pyrroline-5-carboxylate reductase; Region: proC; TIGR00112 663951007647 HMMPfam hit to PF03807, F420_oxidored, score 8.7e-36 663951007648 ribonuclease Z; Region: RNase_Z; TIGR02651 663951007649 HMMPfam hit to PF00753, Lactamase_B, score 2e-09 663951007650 glucose-6-phosphate 1-dehydrogenase; Validated; Region: PRK05722 663951007651 Glucose-6-phosphate dehydrogenase, NAD binding domain; Region: G6PD_N; pfam00479 663951007652 Glucose-6-phosphate dehydrogenase, C-terminal domain; Region: G6PD_C; pfam02781 663951007653 HMMPfam hit to PF00479, G6PD_N, score 2.6e-110 663951007654 HMMPfam hit to PF02781, G6PD_C, score 2.5e-128 663951007655 helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342 663951007656 Bacterial transcription activator, effector binding domain; Region: AraC_E_bind; smart00871 663951007657 PS00041 Bacterial regulatory proteins, araC family signature. 663951007658 HMMPfam hit to PF00165, HTH_AraC, score 0.00013 663951007659 Predicted helix-turn-helix motif with score 1399.000, SD 3.95 at aa 22-43, sequence FNLQELSDYVGLSPYHLDQSFK 663951007660 HMMPfam hit to PF06445, AraC_E_bind, score 1.3e-20 663951007661 alpha,alpha-phosphotrehalase; Region: trehalose_treC; TIGR02403 663951007662 Alpha amylase catalytic domain found in Sucrose isomerases, oligo-1,6-glucosidase (also called isomaltase; sucrase-isomaltase; alpha-limit dextrinase), dextran glucosidase (also called glucan 1,6-alpha-glucosidase), and related proteins; Region: AmyAc_SI_OligoGlu_DGase; cd11333 663951007663 Ca binding site [ion binding]; other site 663951007664 active site 663951007665 catalytic site [active] 663951007666 HMMPfam hit to PF00128, Alpha-amylase, score 3.4e-115 663951007667 Transcriptional regulators [Transcription]; Region: PurR; COG1609 663951007668 Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392 663951007669 DNA binding site [nucleotide binding] 663951007670 domain linker motif; other site 663951007671 Ligand-binding domain of uncharacterized transcription regulator ycjW which is a member of the LacI-GalR family repressors; Region: PBP1_ycjW_transcription_regulator_like; cd06294 663951007672 putative ligand binding site [chemical binding]; other site 663951007673 putative dimerization interface [polypeptide binding]; other site 663951007674 HMMPfam hit to PF00532, Peripla_BP_1, score 7.3e-07 663951007675 HMMPfam hit to PF00356, LacI, score 5.4e-12 663951007676 Predicted helix-turn-helix motif with score 2503.000, SD 7.71 at aa 2-23, sequence VTIKDVALKAGVSPSTVSRVIK 663951007677 PS00356 Bacterial regulatory proteins, lacI family signature. 663951007678 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903 663951007679 This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_16; cd07263 663951007680 HMMPfam hit to PF00903, Glyoxalase, score 2.1e-07 663951007681 6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599 663951007682 6-phosphogluconate dehydrogenase; Validated; Region: PRK09287 663951007683 6-phosphogluconate dehydrogenase, C-terminal domain; Region: 6PGD; pfam00393 663951007684 HMMPfam hit to PF00393, 6PGD, score 1.5e-254 663951007685 PS00461 6-phosphogluconate dehydrogenase signature. 663951007686 HMMPfam hit to PF03446, NAD_binding_2, score 2.2e-90 663951007687 M20 Peptidase T like enzymes specifically cleave tripeptides; Region: M20_peptT_like; cd05683 663951007688 peptidase T-like protein; Region: PepT-like; TIGR01883 663951007689 metal binding site [ion binding]; metal-binding site 663951007690 putative dimer interface [polypeptide binding]; other site 663951007691 HMMPfam hit to PF01546, Peptidase_M20, score 1.4e-19 663951007692 HMMPfam hit to PF07687, M20_dimer, score 7.9e-09 663951007693 PS00759 ArgE / dapE / ACY1 / CPG2 / yscS family signature 2. 663951007694 PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 663951007695 Predicted membrane protein [Function unknown]; Region: COG4129 663951007696 Bacterial protein of unknown function (DUF939); Region: DUF939; pfam06081 663951007697 DUF939 C-terminal domain; Region: DUF939_C; pfam11728 663951007698 HMMPfam hit to PF06081, DUF939, score 6.6e-168 663951007699 4 probable transmembrane helices predicted for SATW20_15100 by TMHMM2.0 at aa 22-44, 57-79, 83-105 and 125-147 663951007700 Disulphide isomerase; Region: Disulph_isomer; pfam06491 663951007701 HMMPfam hit to PF06491, DUF1094, score 3.4e-104 663951007702 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 663951007703 Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849 663951007704 branched-chain alpha-keto acid dehydrogenase subunit E2; Reviewed; Region: PRK11856 663951007705 E3 interaction surface; other site 663951007706 lipoyl attachment site [posttranslational modification]; other site 663951007707 e3 binding domain; Region: E3_binding; pfam02817 663951007708 2-oxoacid dehydrogenases acyltransferase (catalytic domain); Region: 2-oxoacid_dh; pfam00198 663951007709 HMMPfam hit to PF00198, 2-oxoacid_dh, score 1.7e-125 663951007710 HMMPfam hit to PF02817, E3_binding, score 1.9e-11 663951007711 HMMPfam hit to PF00364, Biotin_lipoyl, score 9.7e-28 663951007712 PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 663951007713 Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit [Energy production and conversion]; Region: AcoB; COG0022 663951007714 Pyrimidine (PYR) binding domain of the beta subunits of the E1 components of human pyruvate dehydrogenase complex (E1- PDHc) and related proteins; Region: TPP_PYR_E1-PDHc-beta_like; cd07036 663951007715 alpha subunit interface [polypeptide binding]; other site 663951007716 TPP binding site [chemical binding]; other site 663951007717 heterodimer interface [polypeptide binding]; other site 663951007718 Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780 663951007719 HMMPfam hit to PF02780, Transketolase_C, score 4.3e-49 663951007720 HMMPfam hit to PF02779, Transket_pyr, score 8.2e-67 663951007721 Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit [Energy production and conversion]; Region: AcoA; COG1071 663951007722 Thiamine pyrophosphate (TPP) family, E1 of PDC_ADC_BCADC subfamily, TPP-binding module; composed of proteins similar to the E1 components of the human pyruvate dehydrogenase complex (PDC), the acetoin dehydrogenase complex (ADC) and the branched chain...; Region: TPP_E1_PDC_ADC_BCADC; cd02000 663951007723 tetramer interface [polypeptide binding]; other site 663951007724 TPP-binding site [chemical binding]; other site 663951007725 heterodimer interface [polypeptide binding]; other site 663951007726 phosphorylation loop region [posttranslational modification] 663951007727 HMMPfam hit to PF00676, E1_dh, score 9.1e-106 663951007728 dihydrolipoamide dehydrogenase; Validated; Region: PRK05976 663951007729 Anaerobic glycerol-3-phosphate dehydrogenase [Amino acid transport and metabolism]; Region: GlpB; cl17730 663951007730 Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070 663951007731 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852 663951007732 HMMPfam hit to PF02852, Pyr_redox_dim, score 4.5e-36 663951007733 HMMPfam hit to PF07992, Pyr_redox_2, score 2.3e-53 663951007734 HMMPfam hit to PF00070, Pyr_redox, score 1.3e-26 663951007735 PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 663951007736 ATPase involved in DNA repair [DNA replication, recombination, and repair]; Region: RecN; COG0497 663951007737 ATP-binding cassette domain of RecN; Region: ABC_RecN; cd03241 663951007738 Walker A/P-loop; other site 663951007739 ATP binding site [chemical binding]; other site 663951007740 Q-loop/lid; other site 663951007741 ATP-binding cassette domain of RecN; Region: ABC_RecN; cd03241 663951007742 ABC transporter signature motif; other site 663951007743 Walker B; other site 663951007744 D-loop; other site 663951007745 H-loop/switch region; other site 663951007746 HMMPfam hit to PF02463, SMC_N, score 1.3e-10 663951007747 PS00017 ATP/GTP-binding site motif A (P-loop). 663951007748 arginine repressor; Provisional; Region: PRK04280 663951007749 Arginine repressor, DNA binding domain; Region: Arg_repressor; pfam01316 663951007750 Arginine repressor, C-terminal domain; Region: Arg_repressor_C; pfam02863 663951007751 HMMPfam hit to PF02863, Arg_repressor_C, score 2.6e-28 663951007752 HMMPfam hit to PF01316, Arg_repressor, score 1.6e-31 663951007753 Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; Region: IspA; COG0142 663951007754 Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685 663951007755 substrate binding pocket [chemical binding]; other site 663951007756 chain length determination region; other site 663951007757 substrate-Mg2+ binding site; other site 663951007758 catalytic residues [active] 663951007759 aspartate-rich region 1; other site 663951007760 active site lid residues [active] 663951007761 aspartate-rich region 2; other site 663951007762 HMMPfam hit to PF00348, polyprenyl_synt, score 2.2e-89 663951007763 PS00444 Polyprenyl synthetases signature 2. 663951007764 PS00723 Polyprenyl synthetases signature 1. 663951007765 exodeoxyribonuclease VII small subunit; Provisional; Region: PRK14068 663951007766 HMMPfam hit to PF02609, Exonuc_VII_S, score 2.6e-33 663951007767 exodeoxyribonuclease VII large subunit; Reviewed; Region: xseA; PRK00286 663951007768 ExoVII_LU_OBF: A subfamily of OB folds corresponding to the N-terminal OB-fold domain of Escherichia coli exodeoxyribonuclease VII (ExoVII) large subunit. E. coli ExoVII is composed of two non-identical subunits. E. coli ExoVII is a...; Region: ExoVII_LU_OBF; cd04489 663951007769 generic binding surface II; other site 663951007770 generic binding surface I; other site 663951007771 HMMPfam hit to PF02601, Exonuc_VII_L, score 3e-59 663951007772 HMMPfam hit to PF01336, tRNA_anti, score 1e-12 663951007773 transcription antitermination protein NusB; Reviewed; Region: nusB; PRK00202 663951007774 putative RNA binding site [nucleotide binding]; other site 663951007775 HMMPfam hit to PF01029, NusB, score 1.7e-31 663951007776 Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1302 663951007777 HMMPfam hit to PF03780, DUF322, score 3.4e-25 663951007778 acetyl-CoA carboxylase biotin carboxylase subunit; Validated; Region: PRK08591 663951007779 Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289 663951007780 Carbamoyl-phosphate synthase L chain, ATP binding domain; Region: CPSase_L_D2; pfam02786 663951007781 Biotin carboxylase C-terminal domain; Region: Biotin_carb_C; smart00878 663951007782 HMMPfam hit to PF02785, Biotin_carb_C, score 1.3e-57 663951007783 HMMPfam hit to PF02786, CPSase_L_D2, score 1e-111 663951007784 PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 663951007785 PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 663951007786 HMMPfam hit to PF00289, CPSase_L_chain, score 2.7e-45 663951007787 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 663951007788 acetyl-CoA carboxylase biotin carboxyl carrier protein subunit; Validated; Region: PRK06302 663951007789 The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850 663951007790 carboxyltransferase (CT) interaction site; other site 663951007791 biotinylation site [posttranslational modification]; other site 663951007792 HMMPfam hit to PF00364, Biotin_lipoyl, score 3.4e-30 663951007793 elongation factor P; Validated; Region: PRK00529 663951007794 Elongation factor P (EF-P) KOW-like domain; Region: EFP_N; pfam08207 663951007795 S1_EF-P_repeat_1: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_1; cd04470 663951007796 RNA binding site [nucleotide binding]; other site 663951007797 S1_EF-P_repeat_2: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_2; cd05794 663951007798 RNA binding site [nucleotide binding]; other site 663951007799 HMMPfam hit to PF09285, Elong-fact-P_C, score 3.6e-33 663951007800 PS01275 Elongation factor P signature. 663951007801 HMMPfam hit to PF01132, EFP, score 1.5e-24 663951007802 HMMPfam hit to PF08207, EFP_N, score 2.9e-34 663951007803 Xaa-Pro aminopeptidase [Amino acid transport and metabolism]; Region: PepP; COG0006 663951007804 Creatinase/Prolidase N-terminal domain; Region: Creatinase_N; pfam01321 663951007805 Similar to Prolidase and Aminopeptidase P. The members of this subfamily presumably catalyse hydrolysis of Xaa-Pro dipeptides and/or release of any N-terminal amino acid, including proline, that is linked with proline; Region: APP-like; cd01092 663951007806 active site 663951007807 HMMPfam hit to PF00557, Peptidase_M24, score 5.4e-86 663951007808 PS00491 Aminopeptidase P and proline dipeptidase signature. 663951007809 HMMPfam hit to PF01321, Creatinase_N, score 5e-27 663951007810 Prokaryotic membrane lipoprotein lipid attachment site; Region: LPAM_1; pfam08139 663951007811 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 663951007812 2 probable transmembrane helices predicted for SATW20_15280 by TMHMM2.0 at aa 7-29 and 33-52 663951007813 Lipoate-protein ligase A [Coenzyme metabolism]; Region: LplA; COG0095 663951007814 HMMPfam hit to PF03099, BPL_LipA_LipB, score 9.7e-19 663951007815 Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158 663951007816 active site residue [active] 663951007817 1 probable transmembrane helix predicted for SATW20_15300 by TMHMM2.0 at aa 4-21 663951007818 HMMPfam hit to PF00581, Rhodanese, score 2.8e-21 663951007819 Glycine cleavage system P-protein, alpha- and beta-subunits. This family consists of Glycine cleavage system P-proteins EC:1.4.4.2 from bacterial, mammalian and plant sources. The P protein is part of the glycine decarboxylase multienzyme complex EC:2.1; Region: GDC-P; cd00613 663951007820 tetramer interface [polypeptide binding]; other site 663951007821 pyridoxal 5'-phosphate binding site [chemical binding]; other site 663951007822 catalytic residue [active] 663951007823 HMMPfam hit to PF02347, GDC-P, score 0.0036 663951007824 Glycine cleavage system protein P (pyridoxal-binding), N-terminal domain [Amino acid transport and metabolism]; Region: GcvP; COG0403 663951007825 Glycine cleavage system P-protein, alpha- and beta-subunits. This family consists of Glycine cleavage system P-proteins EC:1.4.4.2 from bacterial, mammalian and plant sources. The P protein is part of the glycine decarboxylase multienzyme complex EC:2.1; Region: GDC-P; cd00613 663951007826 tetramer interface [polypeptide binding]; other site 663951007827 pyridoxal 5'-phosphate binding site [chemical binding]; other site 663951007828 catalytic residue [active] 663951007829 HMMPfam hit to PF02347, GDC-P, score 9.8e-203 663951007830 glycine cleavage system aminomethyltransferase T; Reviewed; Region: gcvT; PRK00389 663951007831 Glycine cleavage T-protein C-terminal barrel domain; Region: GCV_T_C; pfam08669 663951007832 HMMPfam hit to PF08669, GCV_T_C, score 5.5e-33 663951007833 HMMPfam hit to PF01571, GCV_T, score 2.4e-98 663951007834 Shikimate kinase [Amino acid transport and metabolism]; Region: AroK; COG0703 663951007835 Shikimate kinase (SK) is the fifth enzyme in the shikimate pathway, a seven-step biosynthetic pathway which converts erythrose-4-phosphate to chorismic acid, found in bacteria, fungi and plants. Chorismic acid is a important intermediate in the synthesis...; Region: SK; cd00464 663951007836 ADP binding site [chemical binding]; other site 663951007837 magnesium binding site [ion binding]; other site 663951007838 putative shikimate binding site; other site 663951007839 HMMPfam hit to PF01202, SKI, score 5.1e-59 663951007840 PS01128 Shikimate kinase signature. 663951007841 PS00017 ATP/GTP-binding site motif A (P-loop). 663951007842 Competence protein ComGF [Intracellular trafficking and secretion]; Region: ComGF; COG4940 663951007843 HMMPfam hit to PF07963, N_methyl, score 0.0015 663951007844 1 probable transmembrane helix predicted for SATW20_15360 by TMHMM2.0 at aa 10-32 663951007845 Type II secretory pathway, pseudopilin PulG [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PulG; COG2165 663951007846 Competence protein ComGC [Intracellular trafficking and secretion]; Region: ComGC; COG4537 663951007847 HMMPfam hit to PF07963, N_methyl, score 1.6e-05 663951007848 1 probable transmembrane helix predicted for SATW20_15380 by TMHMM2.0 at aa 10-32 663951007849 Type II secretory pathway, component PulF [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PulF; COG1459 663951007850 Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482 663951007851 Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482 663951007852 3 probable transmembrane helices predicted for SATW20_15390 by TMHMM2.0 at aa 123-145, 168-190 and 327-349 663951007853 HMMPfam hit to PF00482, GSPII_F, score 2.9e-16 663951007854 HMMPfam hit to PF00482, GSPII_F, score 1.6e-17 663951007855 Type II/IV secretion system protein; Region: T2SE; pfam00437 663951007856 RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233 663951007857 Walker A motif; other site 663951007858 ATP binding site [chemical binding]; other site 663951007859 Walker B motif; other site 663951007860 HMMPfam hit to PF00437, GSPII_E, score 1.3e-47 663951007861 PS00662 Bacterial type II secretion system protein E signature. 663951007862 PS00017 ATP/GTP-binding site motif A (P-loop). 663951007863 Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849 663951007864 HMMPfam hit to PF00753, Lactamase_B, score 1.5e-38 663951007865 Uncharacterized conserved protein [Function unknown]; Region: COG0011 663951007866 HMMPfam hit to PF01910, DUF77, score 8.4e-54 663951007867 ROK family protein (putative glucokinase); Region: ROK_glcA_fam; TIGR00744 663951007868 Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037 663951007869 HMMPfam hit to PF00480, ROK, score 7.5e-47 663951007870 PS01125 ROK family signature. 663951007871 Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4483 663951007872 HMMPfam hit to PF06014, DUF910, score 6.8e-37 663951007873 Rhomboid family; Region: Rhomboid; pfam01694 663951007874 Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189 663951007875 binding surface 663951007876 TPR motif; other site 663951007877 Tetratricopeptide repeat; Region: TPR_16; pfam13432 663951007878 HMMPfam hit to PF07719, TPR_2, score 0.0011 663951007879 7 probable transmembrane helices predicted for SATW20_15450 by TMHMM2.0 at aa 156-178, 218-237, 242-259,264-286, 293-312, 316-335 and 342-364 663951007880 PS00041 Bacterial regulatory proteins, araC family signature. 663951007881 HMMPfam hit to PF01694, Rhomboid, score 1.3e-50 663951007882 5-formyltetrahydrofolate cyclo-ligase family; Region: 5-FTHF_cyc-lig; pfam01812 663951007883 5,10-methenyltetrahydrofolate synthetase; Region: MTHFS_bact; TIGR02727 663951007884 HMMPfam hit to PF01812, 5-FTHF_cyc-lig, score 6.5e-41 663951007885 50S ribosomal protein L33; Validated; Region: rpmG; PRK00595 663951007886 HMMPfam hit to PF00471, Ribosomal_L33, score 1.1e-22 663951007887 PS00582 Ribosomal protein L33 signature. 663951007888 Cell division protein FtsI/penicillin-binding protein 2 [Cell envelope biogenesis, outer membrane]; Region: FtsI; COG0768 663951007889 Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717 663951007890 Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905 663951007891 HMMPfam hit to PF00905, Transpeptidase, score 2.5e-64 663951007892 HMMPfam hit to PF03717, PBP_dimer, score 3.8e-36 663951007893 1 probable transmembrane helix predicted for SATW20_15480 by TMHMM2.0 at aa 21-43 663951007894 Superoxide dismutase [Inorganic ion transport and metabolism]; Region: SodA; COG0605 663951007895 Iron/manganese superoxide dismutases, alpha-hairpin domain; Region: Sod_Fe_N; pfam00081 663951007896 Iron/manganese superoxide dismutases, C-terminal domain; Region: Sod_Fe_C; pfam02777 663951007897 HMMPfam hit to PF02777, Sod_Fe_C, score 2.1e-74 663951007898 PS00088 Manganese and iron superoxide dismutases signature. 663951007899 HMMPfam hit to PF00081, Sod_Fe_N, score 3.9e-53 663951007900 Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators; Region: Fur_like; cd07153 663951007901 metal binding site 2 [ion binding]; metal-binding site 663951007902 putative DNA binding helix; other site 663951007903 metal binding site 1 [ion binding]; metal-binding site 663951007904 dimer interface [polypeptide binding]; other site 663951007905 structural Zn2+ binding site [ion binding]; other site 663951007906 HMMPfam hit to PF01475, FUR, score 4e-45 663951007907 ABC-type Mn2+/Zn2+ transport systems, permease components [Inorganic ion transport and metabolism]; Region: ZnuB; COG1108 663951007908 Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550 663951007909 ABC-ATPase subunit interface; other site 663951007910 dimer interface [polypeptide binding]; other site 663951007911 putative PBP binding regions; other site 663951007912 HMMPfam hit to PF00950, ABC-3, score 2.9e-55 663951007913 9 probable transmembrane helices predicted for SATW20_15510 by TMHMM2.0 at aa 10-32, 39-61, 66-85, 98-117,137-159, 171-193, 197-219, 226-248 and 253-270 663951007914 ABC-type Mn/Zn transport systems, ATPase component [Inorganic ion transport and metabolism]; Region: ZnuC; COG1121 663951007915 ATP-binding cassette domain of the metal-type transporters; Region: ABC_Metallic_Cations; cd03235 663951007916 HMMPfam hit to PF00005, ABC_tran, score 1.7e-58 663951007917 PS00211 ABC transporters family signature. 663951007918 PS00017 ATP/GTP-binding site motif A (P-loop). 663951007919 endonuclease IV; Provisional; Region: PRK01060 663951007920 AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cd00019 663951007921 AP (apurinic/apyrimidinic) site pocket; other site 663951007922 DNA interaction; other site 663951007923 Metal-binding active site; metal-binding site 663951007924 HMMPfam hit to PF01261, AP_endonuc_2, score 4.5e-53 663951007925 PS00731 AP endonucleases family 2 signature 3. 663951007926 PS00729 AP endonucleases family 2 signature 1. 663951007927 DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker B motif; Region: DEADc; cd00268 663951007928 DEAD-like helicases superfamily; Region: DEXDc; smart00487 663951007929 ATP binding site [chemical binding]; other site 663951007930 Mg++ binding site [ion binding]; other site 663951007931 motif III; other site 663951007932 Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079 663951007933 nucleotide binding region [chemical binding]; other site 663951007934 ATP-binding site [chemical binding]; other site 663951007935 HMMPfam hit to PF00271, Helicase_C, score 9.2e-29 663951007936 HMMPfam hit to PF00270, DEAD, score 5.7e-48 663951007937 Uncharacterized conserved protein [Function unknown]; Region: COG0327 663951007938 NIF3 (NGG1p interacting factor 3); Region: NIF3; pfam01784 663951007939 Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3323 663951007940 Uncharacterized conserved protein [Function unknown]; Region: COG0327 663951007941 NIF3 (NGG1p interacting factor 3); Region: NIF3; pfam01784 663951007942 HMMPfam hit to PF01784, NIF3, score 1.1e-103 663951007943 Predicted SAM-dependent methyltransferase [General function prediction only]; Region: COG2384 663951007944 Family of unknown function (DUF633); Region: DUF633; pfam04816 663951007945 HMMPfam hit to PF04816, DUF633, score 6.4e-119 663951007946 RNA polymerase sigma factor RpoD; Validated; Region: PRK09210 663951007947 Sigma-70 factor, region 1.1; Region: Sigma70_r1_1; pfam03979 663951007948 Sigma-70 factor, region 1.2; Region: Sigma70_r1_2; pfam00140 663951007949 Sigma-70 region 2; Region: Sigma70_r2; pfam04542 663951007950 Sigma-70 region 3; Region: Sigma70_r3; pfam04539 663951007951 Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171 663951007952 DNA binding residues [nucleotide binding] 663951007953 HMMPfam hit to PF04545, Sigma70_r4, score 6.1e-27 663951007954 PS00716 Sigma-70 factors family signature 2. 663951007955 Predicted helix-turn-helix motif with score 1909.000, SD 5.69 at aa 327-348, sequence RTLEEVGKVFGVTRERIRQIEA 663951007956 HMMPfam hit to PF04539, Sigma70_r3, score 1.1e-42 663951007957 HMMPfam hit to PF04542, Sigma70_r2, score 1.4e-28 663951007958 PS00715 Sigma-70 factors family signature 1. 663951007959 HMMPfam hit to PF00140, Sigma70_r1_2, score 1.9e-20 663951007960 HMMPfam hit to PF03979, Sigma70_r1_1, score 8.8e-28 663951007961 DNA primase, catalytic core; Region: dnaG; TIGR01391 663951007962 CHC2 zinc finger; Region: zf-CHC2; pfam01807 663951007963 DNA primase catalytic core, N-terminal domain; Region: Toprim_N; pfam08275 663951007964 TOPRIM_DnaG_primases: The topoisomerase-primase (TORPIM) nucleotidyl transferase/hydrolase domain found in the active site regions of proteins similar to Escherichia coli DnaG. Primases synthesize RNA primers for the initiation of DNA replication. DnaG...; Region: TOPRIM_DnaG_primases; cd03364 663951007965 active site 663951007966 metal binding site [ion binding]; metal-binding site 663951007967 interdomain interaction site; other site 663951007968 HMMPfam hit to PF01751, Toprim, score 1.7e-18 663951007969 HMMPfam hit to PF08275, Toprim_N, score 1.2e-65 663951007970 HMMPfam hit to PF01807, zf-CHC2, score 1.3e-55 663951007971 Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1806 663951007972 HMMPfam hit to PF03618, DUF299, score 2.5e-156 663951007973 HTH domain; Region: HTH_11; cl17392 663951007974 FOG: CBS domain [General function prediction only]; Region: COG0517 663951007975 The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called...; Region: CBS_pair_4; cd04617 663951007976 HMMPfam hit to PF00571, CBS, score 9.4e-17 663951007977 PS00017 ATP/GTP-binding site motif A (P-loop). 663951007978 HMMPfam hit to PF08279, HTH_11, score 3.1e-05 663951007979 glycyl-tRNA synthetase; Provisional; Region: PRK04173 663951007980 Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA. PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268 663951007981 motif 1; other site 663951007982 Glycyl-tRNA synthetase (GlyRS)-like class II core catalytic domain. GlyRS functions as a homodimer in eukaryotes, archaea and some bacteria and as a heterotetramer in the remainder of prokaryotes. It is responsible for the attachment of glycine to the 3...; Region: GlyRS-like_core; cd00774 663951007983 active site 663951007984 motif 2; other site 663951007985 motif 3; other site 663951007986 GlyRS Glycyl-anticodon binding domain. GlyRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: GlyRS_anticodon; cd00858 663951007987 anticodon binding site; other site 663951007988 HMMPfam hit to PF00587, tRNA-synt_2b, score 1.1e-57 663951007989 PS00017 ATP/GTP-binding site motif A (P-loop). 663951007990 PS00179 Aminoacyl-transfer RNA synthetases class-II signature 1. 663951007991 HMMPfam hit to PF03129, HGTP_anticodon, score 1.4e-29 663951007992 DNA repair protein RecO; Region: reco; TIGR00613 663951007993 Recombination protein O N terminal; Region: RecO_N; pfam11967 663951007994 Recombination protein O C terminal; Region: RecO_C; pfam02565 663951007995 HMMPfam hit to PF02565, RecO, score 1.9e-05 663951007996 GTPase Era; Reviewed; Region: era; PRK00089 663951007997 E. coli Ras-like protein (Era) is a multifunctional GTPase; Region: Era; cd04163 663951007998 G1 box; other site 663951007999 GTP/Mg2+ binding site [chemical binding]; other site 663951008000 Switch I region; other site 663951008001 G2 box; other site 663951008002 Switch II region; other site 663951008003 G3 box; other site 663951008004 G4 box; other site 663951008005 G5 box; other site 663951008006 KH-II (K homology RNA-binding domain, type II). KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins (e.g. ribosomal protein S3), transcription factors (e.g. NusA_K), and post-transcriptional...; Region: KH-II; cl00098 663951008007 HMMPfam hit to PF07650, KH_2, score 2.2e-29 663951008008 HMMPfam hit to PF01926, MMR_HSR1, score 6.2e-44 663951008009 PS00017 ATP/GTP-binding site motif A (P-loop). 663951008010 Cytidine deaminase zinc-binding domain. These enzymes are Zn dependent. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a water molecule to form a hydroxide ion that performs a nucleophilic attack on...; Region: cytidine_deaminase; cd01283 663951008011 active site 663951008012 catalytic motif [active] 663951008013 Zn binding site [ion binding]; other site 663951008014 HMMPfam hit to PF00383, dCMP_cyt_deam_1, score 2.2e-15 663951008015 Diacylglycerol kinase [Cell envelope biogenesis, outer membrane]; Region: DgkA; COG0818 663951008016 HMMPfam hit to PF01219, DAGK_prokar, score 2.6e-30 663951008017 3 probable transmembrane helices predicted for SATW20_15650 by TMHMM2.0 at aa 21-38, 43-65 and 86-108 663951008018 PS01069 Prokaryotic diacylglycerol kinase signature. 663951008019 metal-binding heat shock protein; Provisional; Region: PRK00016 663951008020 HMMPfam hit to PF02130, UPF0054, score 3.7e-48 663951008021 PS01306 Uncharacterized protein family UPF0054 signature. 663951008022 Phosphate starvation-inducible protein PhoH, predicted ATPase [Signal transduction mechanisms]; Region: PhoH; COG1702 663951008023 PhoH-like protein; Region: PhoH; pfam02562 663951008024 HMMPfam hit to PF02562, PhoH, score 6.3e-138 663951008025 PS00017 ATP/GTP-binding site motif A (P-loop). 663951008026 HMMPfam hit to PF00013, KH_1, score 0.012 663951008027 hypothetical protein; Provisional; Region: PRK13665 663951008028 HMMPfam hit to PF07251, DUF1432, score 7.7e-258 663951008029 2 probable transmembrane helices predicted for SATW20_15690 by TMHMM2.0 at aa 2-24 and 28-47 663951008030 Membrane-bound serine protease (ClpP class) [Posttranslational modification, protein turnover, chaperones]; Region: NfeD; COG1030 663951008031 HMMPfam hit to PF01957, NfeD, score 9.9e-06 663951008032 4 probable transmembrane helices predicted for SATW20_15700 by TMHMM2.0 at aa 28-50, 57-79, 84-117 and 124-146 663951008033 30S ribosomal protein S21; Reviewed; Region: rpsU; PRK00270 663951008034 HMMPfam hit to PF01165, Ribosomal_S21, score 8.5e-31 663951008035 PS01181 Ribosomal protein S21 signature. 663951008036 2-methylthioadenine synthetase [Translation, ribosomal structure and biogenesis]; Region: MiaB; COG0621 663951008037 Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919 663951008038 Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335 663951008039 FeS/SAM binding site; other site 663951008040 TRAM domain; Region: TRAM; cl01282 663951008041 HMMPfam hit to PF01938, TRAM, score 0.00018 663951008042 HMMPfam hit to PF04055, Radical_SAM, score 3.1e-33 663951008043 PS01278 Uncharacterized protein family UPF0004 signature. 663951008044 HMMPfam hit to PF00919, UPF0004, score 2.5e-42 663951008045 Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1385 663951008046 RNA methyltransferase, RsmE family; Region: TIGR00046 663951008047 HMMPfam hit to PF04452, DUF558, score 4.8e-101 663951008048 Ribosomal protein L11 methyltransferase (PrmA); Region: PrmA; pfam06325 663951008049 S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440 663951008050 S-adenosylmethionine binding site [chemical binding]; other site 663951008051 HMMPfam hit to PF06325, PrmA, score 5.2e-158 663951008052 chaperone protein DnaJ; Provisional; Region: PRK14280 663951008053 DnaJ domain or J-domain. DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257 663951008054 HSP70 interaction site [polypeptide binding]; other site 663951008055 C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cl03262 663951008056 substrate binding site [polypeptide binding]; other site 663951008057 Zinc finger domain of DnaJ and HSP40; Region: DnaJ_zf; cd10719 663951008058 Zn binding sites [ion binding]; other site 663951008059 C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cd10747 663951008060 dimer interface [polypeptide binding]; other site 663951008061 HMMPfam hit to PF01556, DnaJ_C, score 5.5e-79 663951008062 HMMPfam hit to PF00684, DnaJ_CXXCXGXG, score 5.5e-44 663951008063 PS00637 CXXCXGXG dnaJ domain signature. 663951008064 PS00190 Cytochrome c family heme-binding site signature. 663951008065 HMMPfam hit to PF00226, DnaJ, score 5.2e-40 663951008066 PS00636 Nt-dnaJ domain signature. 663951008067 molecular chaperone DnaK; Provisional; Region: dnaK; PRK00290 663951008068 Nucleotide-binding domain of human HSPA9 and similar proteins; Region: HSPA9-Ssq1-like_NBD; cd10234 663951008069 nucleotide binding site [chemical binding]; other site 663951008070 NEF interaction site [polypeptide binding]; other site 663951008071 SBD interface [polypeptide binding]; other site 663951008072 HMMPfam hit to PF00012, HSP70, score 0 663951008073 PS00329 Heat shock hsp70 proteins family signature 2. 663951008074 PS00297 Heat shock hsp70 proteins family signature 1. 663951008075 heat shock protein GrpE; Provisional; Region: PRK14140 663951008076 GrpE is the adenine nucleotide exchange factor of DnaK (Hsp70)-type ATPases. The GrpE dimer binds to the ATPase domain of Hsp70 catalyzing the dissociation of ADP, which enables rebinding of ATP, one step in the Hsp70 reaction cycle in protein folding; Region: GrpE; cd00446 663951008077 dimer interface [polypeptide binding]; other site 663951008078 hsp70 (ATPase domain) interactions [polypeptide binding]; other site 663951008079 HMMPfam hit to PF01025, GrpE, score 2.7e-84 663951008080 PS01071 grpE protein signature. 663951008081 Winged helix-turn-helix transcription repressor, HrcA DNA-binding; Region: HrcA_DNA-bdg; pfam03444 663951008082 heat shock gene repressor HrcA; Region: hrcA; TIGR00331 663951008083 Tubulin C-terminal domain; Region: Tubulin_C; cl10021 663951008084 HMMPfam hit to PF01628, HrcA, score 4.5e-82 663951008085 Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335 663951008086 FeS/SAM binding site; other site 663951008087 HemN C-terminal domain; Region: HemN_C; pfam06969 663951008088 HMMPfam hit to PF06969, HemN_C, score 5e-33 663951008089 HMMPfam hit to PF04055, Radical_SAM, score 4.8e-20 663951008090 GTP-binding protein LepA; Provisional; Region: PRK05433 663951008091 LepA also known as Elongation Factor 4 (EF4); Region: LepA; cd01890 663951008092 G1 box; other site 663951008093 putative GEF interaction site [polypeptide binding]; other site 663951008094 GTP/Mg2+ binding site [chemical binding]; other site 663951008095 Switch I region; other site 663951008096 G2 box; other site 663951008097 G3 box; other site 663951008098 Switch II region; other site 663951008099 G4 box; other site 663951008100 G5 box; other site 663951008101 lepA_II: This subfamily represents the domain II of LepA, a GTP-binding protein localized in the cytoplasmic membrane. The N-terminal domain of LepA shares regions of homology to translation factors. In terms of interaction with the ribosome, EF-G, EF-Tu...; Region: lepA_II; cd03699 663951008102 lepA_C: This family represents the C-terminal region of LepA, a GTP-binding protein localized in the cytoplasmic membrane. LepA is ubiquitous in Bacteria and Eukaryota (e.g. Saccharomyces cerevisiae GUF1p), but is missing from Archaea. LepA exhibits...; Region: lepA_C; cd03709 663951008103 GTP-binding protein LepA C-terminus; Region: LepA_C; pfam06421 663951008104 HMMPfam hit to PF06421, LepA_C, score 1.5e-81 663951008105 HMMPfam hit to PF00679, EFG_C, score 6.8e-42 663951008106 HMMPfam hit to PF03144, GTP_EFTU_D2, score 7.2e-14 663951008107 HMMPfam hit to PF00009, GTP_EFTU, score 8.4e-67 663951008108 PS00301 GTP-binding elongation factors signature. 663951008109 PS00017 ATP/GTP-binding site motif A (P-loop). 663951008110 30S ribosomal protein S20; Reviewed; Region: rpsT; PRK00239 663951008111 HMMPfam hit to PF01649, Ribosomal_S20p, score 6.9e-15 663951008112 DNA polymerase III subunit delta; Reviewed; Region: holA; PRK05574 663951008113 DNA polymerase III, delta subunit; Region: DNA_pol3_delta; pfam06144 663951008114 HMMPfam hit to PF06144, DNA_pol3_delta, score 7.2e-132 663951008115 Predicted membrane metal-binding protein [General function prediction only]; Region: ComEC; COG0658 663951008116 Competence protein; Region: Competence; pfam03772 663951008117 Predicted hydrolase (metallo-beta-lactamase superfamily) [General function prediction only]; Region: ComEC; COG2333 663951008118 Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849 663951008119 HMMPfam hit to PF00753, Lactamase_B, score 6.7e-16 663951008120 9 probable transmembrane helices predicted for SATW20_15830 by TMHMM2.0 at aa 12-34, 38-57, 202-224,239-261, 281-315, 325-347, 360-382, 423-440 and 445-462 663951008121 HMMPfam hit to PF03772, Competence, score 3.1e-80 663951008122 Deoxycytidylate deaminase domain. Deoxycytidylate deaminase catalyzes the deamination of dCMP to dUMP, providing the nucleotide substrate for thymidylate synthase. The enzyme binds Zn++, which is required for catalytic activity. The activity of the...; Region: deoxycytidylate_deaminase; cd01286 663951008123 catalytic motif [active] 663951008124 Zn binding site [ion binding]; other site 663951008125 HMMPfam hit to PF00383, dCMP_cyt_deam_1, score 3.2e-39 663951008126 PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 663951008127 DNA uptake protein and related DNA-binding proteins [DNA replication, recombination, and repair]; Region: ComEA; COG1555 663951008128 SLBB domain; Region: SLBB; pfam10531 663951008129 Helix-hairpin-helix motif; Region: HHH; pfam00633 663951008130 HMMPfam hit to PF00633, HHH, score 2e-08 663951008131 1 probable transmembrane helix predicted for SATW20_15850 by TMHMM2.0 at aa 15-35 663951008132 CDS contains a frameshift after codon 98. Frameshift occurs at a poly T heptamer 663951008133 HMMPfam hit to PF08242, Methyltransf_12, score 4.7e-15 663951008134 Uncharacterized homolog of plant Iojap protein [Function unknown]; Region: COG0799 663951008135 HMMPfam hit to PF02410, DUF143, score 2.9e-39 663951008136 Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077 663951008137 Zn2+ binding site [ion binding]; other site 663951008138 Mg2+ binding site [ion binding]; other site 663951008139 HMMPfam hit to PF01966, HD, score 1.9e-12 663951008140 Nicotinamide/nicotinate mononucleotide adenylyltransferase; Region: NMNAT; cd02165 663951008141 nicotinate (nicotinamide) nucleotide adenylyltransferase; Region: TIGR00482 663951008142 active site 663951008143 (T/H)XGH motif; other site 663951008144 HMMPfam hit to PF01467, CTP_transf_2, score 3.7e-54 663951008145 Predicted RNA-binding protein containing KH domain, possibly ribosomal protein [Translation, ribosomal structure and biogenesis]; Region: COG1534 663951008146 HMMPfam hit to PF01985, CRS1_YhbY, score 1e-42 663951008147 Shikimate 5-dehydrogenase [Amino acid transport and metabolism]; Region: AroE; COG0169 663951008148 Shikimate dehydrogenase substrate binding domain; Region: Shikimate_dh_N; pfam08501 663951008149 NAD(P) binding domain of Shikimate dehydrogenase; Region: NAD_bind_Shikimate_DH; cd01065 663951008150 shikimate binding site; other site 663951008151 NAD(P) binding site [chemical binding]; other site 663951008152 HMMPfam hit to PF01488, Shikimate_DH, score 2.1e-17 663951008153 HMMPfam hit to PF08501, Shikimate_dh_N, score 1.8e-42 663951008154 GTPase YqeH; Provisional; Region: PRK13796 663951008155 Circularly permuted YqeH GTPase; Region: YqeH; cd01855 663951008156 GTP/Mg2+ binding site [chemical binding]; other site 663951008157 G4 box; other site 663951008158 G5 box; other site 663951008159 G1 box; other site 663951008160 Switch I region; other site 663951008161 G2 box; other site 663951008162 G3 box; other site 663951008163 Switch II region; other site 663951008164 HMMPfam hit to PF01926, MMR_HSR1, score 2.7e-09 663951008165 PS00017 ATP/GTP-binding site motif A (P-loop). 663951008166 Predicted hydrolase of the HAD superfamily [General function prediction only]; Region: COG2179 663951008167 Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427 663951008168 active site 663951008169 motif I; other site 663951008170 motif II; other site 663951008171 HMMPfam hit to PF00702, Hydrolase, score 2.1e-06 663951008172 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Validated; Region: PRK05584 663951008173 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Region: MTA/SAH-Nsdase; TIGR01704 663951008174 HMMPfam hit to PF01048, PNP_UDP_1, score 5.8e-87 663951008175 Staphylococcal/Streptococcal toxin, OB-fold domain; Region: Stap_Strp_toxin; pfam01123 663951008176 Staphylococcal/Streptococcal toxin, beta-grasp domain; Region: Stap_Strp_tox_C; pfam02876 663951008177 HMMPfam hit to PF02876, Stap_Strp_tox_C, score 9.1e-32 663951008178 PS00277 Staphylococcal enterotoxin/Streptococcal pyrogenic exotoxin signature 1. 663951008179 HMMPfam hit to PF01123, Stap_Strp_toxin, score 1.7e-20 663951008180 CDS is disrupted by the insertion of an IS element after codon 324 663951008181 Predicted helix-turn-helix motif with score 983.000,SD 2.53 at aa 360-381, sequence LTLIDLENILGVGRVKINNTIK 663951008182 Transposase, Mutator family; Region: Transposase_mut; pfam00872 663951008183 MULE transposase domain; Region: MULE; pfam10551 663951008184 HMMPfam hit to PF00872, Transposase_mut, score 9.8e-228 663951008185 PS01007 Transposases, Mutator family, signature. 663951008186 HMMPfam hit to PF02661, Fic, score 1.5e-35 663951008187 Mn2+ and Fe2+ transporters of the NRAMP family [Inorganic ion transport and metabolism]; Region: MntH; COG1914 663951008188 11 probable transmembrane helices predicted for SATW20_15990 by TMHMM2.0 at aa 21-40, 55-77, 90-109,124-146, 153-175, 195-217, 238-260, 288-310, 323-340,345-367 and 380-402 663951008189 LamB/YcsF family of lactam utilization protein; Region: LamB_YcsF_like; cd10787 663951008190 putative active site [active] 663951008191 HMMPfam hit to PF03746, LamB_YcsF, score 5.7e-174 663951008192 Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289 663951008193 acetyl-CoA carboxylase biotin carboxylase subunit; Validated; Region: PRK08591 663951008194 ATP-grasp domain; Region: ATP-grasp_4; cl17255 663951008195 Biotin carboxylase C-terminal domain; Region: Biotin_carb_C; pfam02785 663951008196 HMMPfam hit to PF02785, Biotin_carb_C, score 4.5e-45 663951008197 HMMPfam hit to PF02786, CPSase_L_D2, score 2.3e-74 663951008198 PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 663951008199 PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 663951008200 HMMPfam hit to PF00289, CPSase_L_chain, score 1.8e-42 663951008201 acetyl-CoA carboxylase biotin carboxyl carrier protein subunit; Validated; Region: PRK06302 663951008202 The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850 663951008203 carboxyltransferase (CT) interaction site; other site 663951008204 biotinylation site [posttranslational modification]; other site 663951008205 HMMPfam hit to PF00364, Biotin_lipoyl, score 4.5e-20 663951008206 Allophanate hydrolase subunit 2 [Amino acid transport and metabolism]; Region: DUR1; COG1984 663951008207 HMMPfam hit to PF02626, AHS2, score 5.1e-65 663951008208 Allophanate hydrolase subunit 1; Region: AHS1; smart00796 663951008209 Allophanate hydrolase subunit 1 [Amino acid transport and metabolism]; Region: DUR1; COG2049 663951008210 HMMPfam hit to PF02682, AHS1, score 4.4e-64 663951008211 transcription elongation factor GreA; Reviewed; Region: greA; PRK00226 663951008212 Transcription elongation factor, N-terminal; Region: GreA_GreB_N; pfam03449 663951008213 Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272 663951008214 HMMPfam hit to PF01272, GreA_GreB, score 1.9e-19 663951008215 PS00830 Prokaryotic transcription elongation factors signature 2. 663951008216 HMMPfam hit to PF03449, GreA_GreB_N, score 1.2e-32 663951008217 PS00829 Prokaryotic transcription elongation factors signature 1. 663951008218 Uridine kinase [Nucleotide transport and metabolism]; Region: Udk; COG0572 663951008219 Uridine monophosphate kinase (UMPK, EC 2.7.1.48), also known as uridine kinase or uridine-cytidine kinase (UCK), catalyzes the reversible phosphoryl transfer from ATP to uridine or cytidine to yield UMP or CMP. In the primidine nucleotide-salvage pathway; Region: UMPK; cd02023 663951008220 Sugar specificity; other site 663951008221 Pyrimidine base specificity; other site 663951008222 ATP-binding site [chemical binding]; other site 663951008223 HMMPfam hit to PF00485, PRK, score 1.5e-51 663951008224 PS00017 ATP/GTP-binding site motif A (P-loop). 663951008225 Collagenase and related proteases [Posttranslational modification, protein turnover, chaperones]; Region: COG0826 663951008226 TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl17186 663951008227 Peptidase family U32; Region: Peptidase_U32; pfam01136 663951008228 HMMPfam hit to PF01136, Peptidase_U32, score 5.2e-130 663951008229 PS01276 Peptidase family U32 signature. 663951008230 Collagenase and related proteases [Posttranslational modification, protein turnover, chaperones]; Region: COG0826 663951008231 Peptidase family U32; Region: Peptidase_U32; pfam01136 663951008232 HMMPfam hit to PF01136, Peptidase_U32, score 3.4e-71 663951008233 PS00018 EF-hand calcium-binding domain. 663951008234 Predicted O-methyltransferase [General function prediction only]; Region: COG4122 663951008235 S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440 663951008236 S-adenosylmethionine binding site [chemical binding]; other site 663951008237 HMMPfam hit to PF01596, Methyltransf_3, score 3.4e-10 663951008238 hypothetical protein; Provisional; Region: PRK13678 663951008239 HMMPfam hit to PF06949, DUF1292, score 4.2e-46 663951008240 Predicted endonuclease involved in recombination (possible Holliday junction resolvase in Mycoplasmas and B. subtilis) [DNA replication, recombination, and repair]; Region: COG0816 663951008241 HMMPfam hit to PF03652, UPF0081, score 1.5e-47 663951008242 hypothetical protein; Provisional; Region: PRK05473 663951008243 HMMPfam hit to PF06135, DUF965, score 1.7e-48 663951008244 alanyl-tRNA synthetase; Reviewed; Region: alaS; PRK00252 663951008245 Alanyl-tRNA synthetase (AlaRS) class II core catalytic domain. AlaRS is a homodimer. It is responsible for the attachment of alanine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: AlaRS_core; cd00673 663951008246 motif 1; other site 663951008247 active site 663951008248 motif 2; other site 663951008249 motif 3; other site 663951008250 Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; smart00863 663951008251 DHHA1 domain; Region: DHHA1; pfam02272 663951008252 HMMPfam hit to PF02272, DHHA1, score 7.6e-21 663951008253 HMMPfam hit to PF07973, tRNA_SAD, score 9.3e-22 663951008254 HMMPfam hit to PF01411, tRNA-synt_2c, score 3.1e-301 663951008255 PS00339 Aminoacyl-transfer RNA synthetases class-II signature 2. 663951008256 helicase, putative, RecD/TraA family; Region: recD_rel; TIGR01448 663951008257 AAA domain; Region: AAA_30; pfam13604 663951008258 Family description; Region: UvrD_C_2; pfam13538 663951008259 PS00017 ATP/GTP-binding site motif A (P-loop). 663951008260 Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189 663951008261 binding surface 663951008262 TPR motif; other site 663951008263 Anaphase-promoting complex, cyclosome, subunit 3; Region: Apc3; pfam12895 663951008264 Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189 663951008265 binding surface 663951008266 TPR motif; other site 663951008267 TPR repeat; Region: TPR_11; pfam13414 663951008268 HMMPfam hit to PF00515, TPR_1, score 2.5e-05 663951008269 HMMPfam hit to PF07719, TPR_2, score 0.0028 663951008270 HMMPfam hit to PF00515, TPR_1, score 0.12 663951008271 HMMPfam hit to PF00515, TPR_1, score 2.8e-06 663951008272 HMMPfam hit to PF07719, TPR_2, score 2e-05 663951008273 Predicted tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain [Translation, ribosomal structure and biogenesis]; Region: TrmU; COG0482 663951008274 tRNA methyl transferase. This family represents tRNA(5-methylaminomethyl-2-thiouridine)-methyltransferase which is involved in the biosynthesis of the modified nucleoside 5-methylaminomethyl-2-thiouridine present in the wobble position of some tRNAs; Region: tRNA_Me_trans; cd01998 663951008275 HMMPfam hit to PF03054, tRNA_Me_trans, score 5.3e-219 663951008276 Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes [Amino acid transport and metabolism]; Region: NifS; COG1104 663951008277 cysteine desulfurase NifS; Region: FeS_nifS; TIGR03402 663951008278 pyridoxal 5'-phosphate binding pocket [chemical binding]; other site 663951008279 catalytic residue [active] 663951008280 HMMPfam hit to PF00266, Aminotran_5, score 8.5e-89 663951008281 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 663951008282 PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 663951008283 luciferase family oxidoreductase, group 1; Region: oxido_grp_1; TIGR03558 663951008284 Flavin-utilizing monoxygenases; Region: Flavin_utilizing_monoxygenases; cl07892 663951008285 HMMPfam hit to PF00296, Bac_luciferase, score 1.6e-16 663951008286 Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3237 663951008287 HMMPfam hit to PF05532, CsbD, score 4.7e-23 663951008288 Predicted transcriptional regulator [Transcription]; Region: COG1959 663951008289 Transcriptional regulator; Region: Rrf2; pfam02082 663951008290 HMMPfam hit to PF02082, Rrf2, score 4.2e-50 663951008291 PS01332 Uncharacterized protein family UPF0074 signature. 663951008292 recombination factor protein RarA; Reviewed; Region: PRK13342 663951008293 The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009 663951008294 Walker A motif; other site 663951008295 ATP binding site [chemical binding]; other site 663951008296 Walker B motif; other site 663951008297 arginine finger; other site 663951008298 MgsA AAA+ ATPase C terminal; Region: MgsA_C; pfam12002 663951008299 HMMPfam hit to PF00004, AAA, score 5.4e-20 663951008300 PS00017 ATP/GTP-binding site motif A (P-loop). 663951008301 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1 [Coenzyme metabolism]; Region: COG1179 663951008302 Family of activating enzymes (E1) of ubiquitin-like proteins related to the E.coli hypothetical protein ygdL. The common reaction mechanism catalyzed by E1-like enzymes begins with a nucleophilic attack of the C-terminal carboxylate of the ubiquitin-like...; Region: YgdL_like; cd00755 663951008303 putative ATP binding site [chemical binding]; other site 663951008304 putative substrate interface [chemical binding]; other site 663951008305 HMMPfam hit to PF00899, ThiF, score 1.7e-53 663951008306 aspartyl-tRNA synthetase; Validated; Region: aspS; PRK00476 663951008307 EcAspRS_like_N: N-terminal, anticodon recognition domain of the type found in Escherichia coli aspartyl-tRNA synthetase (AspRS), the human mitochondrial (mt) AspRS-2, the discriminating (D) Thermus thermophilus AspRS-1, and the nondiscriminating (ND)...; Region: EcAspRS_like_N; cd04317 663951008308 dimer interface [polypeptide binding]; other site 663951008309 anticodon binding site; other site 663951008310 Asp tRNA synthetase (aspRS) class II core domain. Class II assignment is based upon its structure and the presence of three characteristic sequence motifs. AspRS is a homodimer, which attaches a specific amino acid to the 3' OH group of ribose of...; Region: AspRS_core; cd00777 663951008311 homodimer interface [polypeptide binding]; other site 663951008312 motif 1; other site 663951008313 active site 663951008314 motif 2; other site 663951008315 GAD domain; Region: GAD; pfam02938 663951008316 Asp tRNA synthetase (aspRS) class II core domain. Class II assignment is based upon its structure and the presence of three characteristic sequence motifs. AspRS is a homodimer, which attaches a specific amino acid to the 3' OH group of ribose of...; Region: AspRS_core; cd00777 663951008317 motif 3; other site 663951008318 HMMPfam hit to PF00152, tRNA-synt_2, score 5.2e-231 663951008319 PS00339 Aminoacyl-transfer RNA synthetases class-II signature 2. 663951008320 HMMPfam hit to PF02938, GAD, score 2.8e-36 663951008321 PS00179 Aminoacyl-transfer RNA synthetases class-II signature 1. 663951008322 HMMPfam hit to PF01336, tRNA_anti, score 1.9e-27 663951008323 histidyl-tRNA synthetase; Reviewed; Region: hisS; PRK00037 663951008324 Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core domain. HisRS is a homodimer. It is responsible for the attachment of histidine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for...; Region: HisRS-like_core; cd00773 663951008325 dimer interface [polypeptide binding]; other site 663951008326 motif 1; other site 663951008327 active site 663951008328 motif 2; other site 663951008329 motif 3; other site 663951008330 HisRS Histidyl-anticodon binding domain. HisRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: HisRS_anticodon; cd00859 663951008331 anticodon binding site; other site 663951008332 HMMPfam hit to PF03129, HGTP_anticodon, score 8e-22 663951008333 HMMPfam hit to PF00587, tRNA-synt_2b, score 1e-60 663951008334 Bacterial SH3 domain homologues; Region: SH3b; smart00287 663951008335 N-acetylmuramoyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: AmiC; COG0860 663951008336 N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696 663951008337 active site 663951008338 metal binding site [ion binding]; metal-binding site 663951008339 HMMPfam hit to PF01520, Amidase_3, score 5.9e-76 663951008340 HMMPfam hit to PF08239, SH3_3, score 0.00065 663951008341 1 probable transmembrane helix predicted for SATW20_16260 by TMHMM2.0 at aa 19-36 663951008342 D-Tyrosyl-tRNAtyr deacylases; a class of tRNA-dependent hydrolases which are capable of hydrolyzing the ester bond of D-Tyrosyl-tRNA reducing the level of cellular D-Tyrosine while recycling the peptidyl-tRNA; found in bacteria and in eukaryotes but not...; Region: Dtyr_deacylase; cd00563 663951008343 putative active site [active] 663951008344 dimerization interface [polypeptide binding]; other site 663951008345 putative tRNAtyr binding site [nucleotide binding]; other site 663951008346 HMMPfam hit to PF02580, Tyr_Deacylase, score 1.8e-84 663951008347 Guanosine polyphosphate pyrophosphohydrolases/synthetases [Signal transduction mechanisms / Transcription]; Region: SpoT; COG0317 663951008348 Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077 663951008349 Zn2+ binding site [ion binding]; other site 663951008350 Mg2+ binding site [ion binding]; other site 663951008351 Nucleotidyltransferase (NT) domain of RelA- and SpoT-like ppGpp synthetases and hydrolases; Region: NT_Rel-Spo_like; cd05399 663951008352 synthetase active site [active] 663951008353 NTP binding site [chemical binding]; other site 663951008354 metal binding site [ion binding]; metal-binding site 663951008355 TGS_RelA_SpoT: The RelA (SpoT) protein, also referred to as ppGpp hydrolase/synthetase, is a ribosome-associated protein that is activated during amino acid starvation and thought to mediate the stringent response. RelA contains a TGS domain, named after...; Region: TGS_RelA_SpoT; cd01668 663951008356 ACT domain found C-terminal of the RelA/SpoT domains; Region: ACT_RelA-SpoT; cd04876 663951008357 HMMPfam hit to PF01842, ACT, score 1.4e-06 663951008358 HMMPfam hit to PF02824, TGS, score 1.3e-26 663951008359 HMMPfam hit to PF04607, RelA_SpoT, score 1.2e-51 663951008360 HMMPfam hit to PF01966, HD, score 5.3e-18 663951008361 Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223 663951008362 active site 663951008363 HMMPfam hit to PF00156, Pribosyltran, score 7.5e-48 663951008364 single-stranded-DNA-specific exonuclease RecJ; Region: recJ; TIGR00644 663951008365 DHH family; Region: DHH; pfam01368 663951008366 DHHA1 domain; Region: DHHA1; pfam02272 663951008367 Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4199 663951008368 HMMPfam hit to PF02272, DHHA1, score 1.1e-10 663951008369 HMMPfam hit to PF01368, DHH, score 7.4e-53 663951008370 bifunctional preprotein translocase subunit SecD/SecF; Reviewed; Region: PRK13024 663951008371 SecD/SecF GG Motif; Region: Sec_GG; pfam07549 663951008372 protein-export membrane protein, SecD/SecF family; Region: 2A0604s01; TIGR00916 663951008373 Protein export membrane protein; Region: SecD_SecF; pfam02355 663951008374 HMMPfam hit to PF02355, SecD_SecF, score 3.8e-77 663951008375 12 probable transmembrane helices predicted for SATW20_16310 by TMHMM2.0 at aa 7-29, 262-281, 288-310,314-336, 356-378, 388-410, 456-478, 574-591, 598-620,625-647, 681-703 and 707-729 663951008376 HMMPfam hit to PF07549, Sec_GG, score 0.00031 663951008377 HMMPfam hit to PF07549, Sec_GG, score 0.00026 663951008378 Preprotein translocase subunit; Region: YajC; pfam02699 663951008379 HMMPfam hit to PF02699, YajC, score 4.7e-26 663951008380 1 probable transmembrane helix predicted for SATW20_16320 by TMHMM2.0 at aa 4-21 663951008381 queuine tRNA-ribosyltransferase; Provisional; Region: tgt; PRK00112 663951008382 Queuine/archaeosine tRNA-ribosyltransferase [Translation, ribosomal structure and biogenesis]; Region: Tgt; COG0343 663951008383 HMMPfam hit to PF01702, TGT, score 3.5e-161 663951008384 S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Provisional; Region: queA; PRK00147 663951008385 S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Region: queA; TIGR00113 663951008386 HMMPfam hit to PF02547, Queuosine_synth, score 5.5e-119 663951008387 Holliday junction DNA helicase RuvB; Reviewed; Region: ruvB; PRK00080 663951008388 The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009 663951008389 Walker A motif; other site 663951008390 ATP binding site [chemical binding]; other site 663951008391 Walker B motif; other site 663951008392 arginine finger; other site 663951008393 Holliday junction DNA helicase ruvB C-terminus; Region: RuvB_C; pfam05491 663951008394 HMMPfam hit to PF05491, RuvB_C, score 1.2e-53 663951008395 HMMPfam hit to PF00004, AAA, score 5e-34 663951008396 PS00017 ATP/GTP-binding site motif A (P-loop). 663951008397 HMMPfam hit to PF05496, RuvB_N, score 3.4e-27 663951008398 Holliday junction DNA helicase RuvA; Reviewed; Region: ruvA; PRK00116 663951008399 RuvA N terminal domain; Region: RuvA_N; pfam01330 663951008400 RuvA, C-terminal domain; Region: RuvA_C; pfam07499 663951008401 HMMPfam hit to PF07499, RuvA_C, score 1.1e-10 663951008402 HMMPfam hit to PF01330, RuvA_N, score 7.2e-29 663951008403 ACT domain-containing protein [General function prediction only]; Region: PheB; COG4492 663951008404 ACT domains are commonly involved in specifically binding an amino acid or other small ligand leading to regulation of the enzyme; Region: ACT; cl09141 663951008405 HMMPfam hit to PF01842, ACT, score 0.012 663951008406 Predicted helix-turn-helix motif with score 1182.000, SD 3.21 at aa 37-58, sequence LSIYDAVKQFDLSRSAFYKYRE 663951008407 GTPase CgtA; Reviewed; Region: obgE; PRK12297 663951008408 GTP1/OBG; Region: GTP1_OBG; pfam01018 663951008409 Obg GTPase; Region: Obg; cd01898 663951008410 G1 box; other site 663951008411 GTP/Mg2+ binding site [chemical binding]; other site 663951008412 Switch I region; other site 663951008413 G2 box; other site 663951008414 G3 box; other site 663951008415 Switch II region; other site 663951008416 G4 box; other site 663951008417 G5 box; other site 663951008418 Domain of unknown function (DUF1967); Region: DUF1967; pfam09269 663951008419 HMMPfam hit to PF09269, DUF1967, score 5e-38 663951008420 HMMPfam hit to PF01926, MMR_HSR1, score 1.4e-40 663951008421 PS00905 GTP1/OBG family signature. 663951008422 PS00017 ATP/GTP-binding site motif A (P-loop). 663951008423 HMMPfam hit to PF01018, GTP1_OBG, score 4.2e-92 663951008424 50S ribosomal protein L27; Validated; Region: rpmA; PRK05435 663951008425 HMMPfam hit to PF01016, Ribosomal_L27, score 1e-52 663951008426 PS00831 Ribosomal protein L27 signature. 663951008427 Predicted ribosomal protein [Translation, ribosomal structure and biogenesis]; Region: COG2868 663951008428 HMMPfam hit to PF04327, DUF464, score 5.2e-53 663951008429 50S ribosomal protein L21/unknown domain fusion protein; Provisional; Region: PRK12278 663951008430 50S ribosomal protein L21; Validated; Region: rplU; PRK05573 663951008431 HMMPfam hit to PF00829, Ribosomal_L21p, score 6.6e-62 663951008432 Cell shape-determining protein [Cell envelope biogenesis, outer membrane]; Region: MreD; COG2891 663951008433 HMMPfam hit to PF04093, MreD, score 2.1e-63 663951008434 5 probable transmembrane helices predicted for SATW20_16420 by TMHMM2.0 at aa 5-27, 42-64, 71-93, 103-125 and 137-159 663951008435 Cell shape-determining protein [Cell envelope biogenesis, outer membrane]; Region: MreC; COG1792 663951008436 rod shape-determining protein MreC; Region: MreC; pfam04085 663951008437 HMMPfam hit to PF04085, MreC, score 6.3e-73 663951008438 1 probable transmembrane helix predicted for SATW20_16430 by TMHMM2.0 at aa 10-28 663951008439 1 probable transmembrane helix predicted for SATW20_16440 by TMHMM2.0 at aa 3-25 663951008440 3 probable transmembrane helices predicted for SATW20_16450 by TMHMM2.0 at aa 4-21, 30-52 and 62-84 663951008441 CDS is disrupted by the insertion of a Tn554 transposon after codon 180 663951008442 HMMPfam hit to PF04002, RadC, score 1.6e-54 663951008443 Transposon Tn554 663951008444 S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440 663951008445 S-adenosylmethionine binding site [chemical binding]; other site 663951008446 HMMPfam hit to PF08242, Methyltransf_12, score 3.4e-22 663951008447 Ribosomal RNA adenine dimethylase; Region: RrnaAD; pfam00398 663951008448 S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440 663951008449 S-adenosylmethionine binding site [chemical binding]; other site 663951008450 HMMPfam hit to PF00398, RrnaAD, score 1.9e-108 663951008451 PS01131 Ribosomal RNA adenine dimethylases signature. 663951008452 aminoglycoside resistance protein; Provisional; Region: PRK13746 663951008453 Nucleotidyltransferase (NT) domain of Staphylococcus aureus kanamycin nucleotidyltransferase, and similar proteins; Region: NT_KNTase_like; cd05403 663951008454 active site 663951008455 NTP binding site [chemical binding]; other site 663951008456 metal binding triad [ion binding]; metal-binding site 663951008457 antibiotic binding site [chemical binding]; other site 663951008458 Domain of unknown function (DUF4111); Region: DUF4111; pfam13427 663951008459 HMMPfam hit to PF01909, NTP_transf_2, score 1.4e-15 663951008460 Predicted helix-turn-helix motif with score 1150.000, SD 3.10 at aa 40-61, sequence INFNSIAKEANVSKSWLYKEHD 663951008461 tyrosine recombinase XerC; Region: recomb_XerC; TIGR02224 663951008462 Phage integrase, N-terminal SAM-like domain; Region: Phage_integr_N; cl12235 663951008463 DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213 663951008464 active site 663951008465 DNA binding site [nucleotide binding] 663951008466 Int/Topo IB signature motif; other site 663951008467 HMMPfam hit to PF00589, Phage_integrase, score 1e-38 663951008468 Phage integrase, N-terminal SAM-like domain; Region: Phage_integr_N; cl12235 663951008469 tyrosine recombinase XerD; Region: recomb_XerD; TIGR02225 663951008470 Tn544A and related transposases, DNA breaking-rejoining enzymes, integrase/recombinases, C-terminal catalytic domain. This CD includes various bacterial transposases similar to TnpA from transposon Tn554; Region: INT_Tn554A_C; cd01194 663951008471 Int/Topo IB signature motif; other site 663951008472 HMMPfam hit to PF00589, Phage_integrase, score 6.1e-55 663951008473 HMMPfam hit to PF02899, Phage_integr_N, score 4.6e-05 663951008474 PS01302 DNA repair protein radC family signature. 663951008475 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases [Cell motility and secretion / Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: PulO; COG1989 663951008476 Bacterial Peptidase A24 N-terminal domain; Region: DiS_P_DiS; pfam06750 663951008477 Type IV leader peptidase family; Region: Peptidase_A24; pfam01478 663951008478 6 probable transmembrane helices predicted for SATW20_16530 by TMHMM2.0 at aa 68-86, 90-109, 122-144,154-176, 178-200 and 205-223 663951008479 HMMPfam hit to PF01478, Peptidase_A24, score 2.1e-17 663951008480 HMMPfam hit to PF06750, DiS_P_DiS, score 2e-39 663951008481 Folylpolyglutamate synthase [Coenzyme metabolism]; Region: FolC; COG0285 663951008482 Mur ligase middle domain; Region: Mur_ligase_M; pfam08245 663951008483 Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875 663951008484 HMMPfam hit to PF02875, Mur_ligase_C, score 0.0031 663951008485 HMMPfam hit to PF08245, Mur_ligase_M, score 6.9e-06 663951008486 valyl-tRNA synthetase; Reviewed; Region: valS; PRK05729 663951008487 nucleotidyl transferase superfamily; Region: nt_trans; cl00015 663951008488 active site 663951008489 HIGH motif; other site 663951008490 nucleotide binding site [chemical binding]; other site 663951008491 Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603 663951008492 catalytic core domain of valyl-tRNA synthetases; Region: ValRS_core; cd00817 663951008493 active site 663951008494 KMSKS motif; other site 663951008495 Anticodon-binding domain of valyl tRNA synthetases; Region: Anticodon_Ia_Val; cd07962 663951008496 tRNA binding surface [nucleotide binding]; other site 663951008497 anticodon binding site; other site 663951008498 Valyl tRNA synthetase tRNA binding arm; Region: Val_tRNA-synt_C; pfam10458 663951008499 HMMPfam hit to PF08264, Anticodon_1, score 2.2e-67 663951008500 HMMPfam hit to PF00133, tRNA-synt_1, score 0 663951008501 PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 663951008502 Methyladenine glycosylase; Region: Adenine_glyco; pfam03352 663951008503 HMMPfam hit to PF03352, Adenine_glyco, score 8.8e-127 663951008504 membrane protein AbrB duplication; Region: Gneg_AbrB_dup; TIGR03082 663951008505 Putative ammonia monooxygenase; Region: AmoA; pfam05145 663951008506 membrane protein AbrB duplication; Region: Gneg_AbrB_dup; TIGR03082 663951008507 HMMPfam hit to PF05145, AmoA, score 2.3e-166 663951008508 10 probable transmembrane helices predicted for SATW20_16570 by TMHMM2.0 at aa 13-35, 60-82, 89-111,121-138, 145-167, 190-212, 219-241, 275-297, 304-326 and 336-354 663951008509 glutamate-1-semialdehyde aminotransferase; Provisional; Region: PRK00062 663951008510 Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610 663951008511 inhibitor-cofactor binding pocket; inhibition site 663951008512 pyridoxal 5'-phosphate binding site [chemical binding]; other site 663951008513 catalytic residue [active] 663951008514 HMMPfam hit to PF00202, Aminotran_3, score 6.6e-86 663951008515 PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 663951008516 Porphobilinogen synthase (PBGS), which is also called delta-aminolevulinic acid dehydratase (ALAD), catalyzes the condensation of two 5-aminolevulinic acid (ALA) molecules to form the pyrrole porphobilinogen (PBG), which is the second step in the...; Region: ALAD_PBGS; cd00384 663951008517 dimer interface [polypeptide binding]; other site 663951008518 active site 663951008519 Schiff base residues; other site 663951008520 HMMPfam hit to PF00490, ALAD, score 5.2e-195 663951008521 PS00169 Delta-aminolevulinic acid dehydratase active site. 663951008522 Uroporphyrinogen-III synthase [Coenzyme metabolism]; Region: HemD; COG1587 663951008523 Uroporphyrinogen-III synthase (HemD) catalyzes the asymmetrical cyclization of tetrapyrrole (linear) to uroporphyrinogen-III, the fourth step in the biosynthesis of heme. This ubiquitous enzyme is present in eukaryotes, bacteria and archaea. Mutations in...; Region: HemD; cd06578 663951008524 active site 663951008525 HMMPfam hit to PF02602, HEM4, score 1.2e-25 663951008526 porphobilinogen deaminase; Reviewed; Region: hemC; PRK00072 663951008527 Hydroxymethylbilane synthase (HMBS), also known as porphobilinogen deaminase (PBGD), is an intermediate enzyme in the biosynthetic pathway of tetrapyrrolic ring systems, such as heme, chlorophylls, and vitamin B12. HMBS catalyzes the conversion of...; Region: HMBS; cd00494 663951008528 domain interfaces; other site 663951008529 active site 663951008530 HMMPfam hit to PF03900, Porphobil_deamC, score 2.3e-35 663951008531 PS00533 Porphobilinogen deaminase cofactor-binding site. 663951008532 HMMPfam hit to PF01379, Porphobil_deam, score 3.1e-141 663951008533 ABC-type transport system involved in cytochrome c biogenesis, permease component [Posttranslational modification, protein turnover, chaperones]; Region: CcmC; COG0755 663951008534 8 probable transmembrane helices predicted for SATW20_16620 by TMHMM2.0 at aa 4-26, 38-60, 65-87, 92-114,134-156, 184-206, 221-240 and 247-269 663951008535 HMMPfam hit to PF01578, Cytochrom_C_asm, score 5.2e-07 663951008536 glutamyl-tRNA reductase; Reviewed; Region: hemA; PRK00045 663951008537 NADP-binding domain of glutamyl-tRNA reductase; Region: NAD_bind_Glutamyl_tRNA_reduct; cd05213 663951008538 tRNA; other site 663951008539 putative tRNA binding site [nucleotide binding]; other site 663951008540 putative NADP binding site [chemical binding]; other site 663951008541 Glutamyl-tRNAGlu reductase, dimerisation domain; Region: GlutR_dimer; pfam00745 663951008542 HMMPfam hit to PF00745, GlutR_dimer, score 4.9e-33 663951008543 HMMPfam hit to PF01488, Shikimate_DH, score 1.5e-66 663951008544 HMMPfam hit to PF05201, GlutR_N, score 1.8e-79 663951008545 PS00747 Glutamyl-tRNA reductase signature. 663951008546 YihA (EngB) GTPase family; Region: YihA_EngB; cd01876 663951008547 G1 box; other site 663951008548 GTP/Mg2+ binding site [chemical binding]; other site 663951008549 Switch I region; other site 663951008550 G2 box; other site 663951008551 G3 box; other site 663951008552 Switch II region; other site 663951008553 G4 box; other site 663951008554 G5 box; other site 663951008555 HMMPfam hit to PF01926, MMR_HSR1, score 6e-31 663951008556 PS00017 ATP/GTP-binding site motif A (P-loop). 663951008557 ATP-dependent protease ATP-binding subunit ClpX; Provisional; Region: clpX; PRK05342 663951008558 ClpX C4-type zinc finger; Region: zf-C4_ClpX; pfam06689 663951008559 The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009 663951008560 Walker A motif; other site 663951008561 ATP binding site [chemical binding]; other site 663951008562 Walker B motif; other site 663951008563 C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086 663951008564 HMMPfam hit to PF07724, AAA_2, score 5.8e-81 663951008565 PS00017 ATP/GTP-binding site motif A (P-loop). 663951008566 HMMPfam hit to PF06689, zf-C4_ClpX, score 9.5e-25 663951008567 trigger factor; Provisional; Region: tig; PRK01490 663951008568 FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254 663951008569 Bacterial trigger factor protein (TF) C-terminus; Region: Trigger_C; pfam05698 663951008570 HMMPfam hit to PF05698, Trigger_C, score 7.6e-65 663951008571 HMMPfam hit to PF00254, FKBP_C, score 1.7e-26 663951008572 HMMPfam hit to PF05697, Trigger_N, score 3.8e-71 663951008573 Predicted phosphoesterase (MutT family) [General function prediction only]; Region: COG4112 663951008574 HMMPfam hit to PF00293, NUDIX, score 0.024 663951008575 Ribosomal protein L20; Region: Ribosomal_L20; cd07026 663951008576 23S rRNA binding site [nucleotide binding]; other site 663951008577 L21 binding site [polypeptide binding]; other site 663951008578 L13 binding site [polypeptide binding]; other site 663951008579 HMMPfam hit to PF00453, Ribosomal_L20, score 1.1e-68 663951008580 PS00937 Ribosomal protein L20 signature. 663951008581 50S ribosomal protein L35; Reviewed; Region: rpmI; PRK00172 663951008582 HMMPfam hit to PF01632, Ribosomal_L35p, score 4e-29 663951008583 PS00936 Ribosomal protein L35 signature. 663951008584 translation initiation factor IF-3; Reviewed; Region: infC; PRK00028 663951008585 Translation initiation factor IF-3, N-terminal domain; Region: IF3_N; pfam05198 663951008586 Translation initiation factor IF-3, C-terminal domain; Region: IF3_C; pfam00707 663951008587 HMMPfam hit to PF00707, IF3_C, score 6.4e-50 663951008588 HMMPfam hit to PF05198, IF3_N, score 1e-50 663951008589 PS00938 Initiation factor 3 signature. 663951008590 lysine transporter; Provisional; Region: PRK10836 663951008591 HMMPfam hit to PF00324, AA_permease, score 6.5e-163 663951008592 12 probable transmembrane helices predicted for SATW20_16720 by TMHMM2.0 at aa 21-43, 47-69, 101-123,128-150, 162-184, 199-221, 250-269, 295-317, 347-366,376-398, 419-438 and 453-470 663951008593 PS00017 ATP/GTP-binding site motif A (P-loop). 663951008594 PS00218 Amino acid permeases signature. 663951008595 threonyl-tRNA synthetase; Reviewed; Region: thrS; PRK00413 663951008596 TGS _ThrRS_N: ThrRS (threonyl-tRNA Synthetase) is a class II tRNA synthetase that couples threonine to its cognate tRNA. In addition to its catalytic and anticodon-binding domains, ThrRS has an N-terminal TGS domain, named after the ThrRS, GTPase, and...; Region: TGS_ThrRS_N; cd01667 663951008597 Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; smart00863 663951008598 Threonyl-tRNA synthetase (ThrRS) class II core catalytic domain. ThrRS is a homodimer. It is responsible for the attachment of threonine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ThrRS_core; cd00771 663951008599 active site 663951008600 dimer interface [polypeptide binding]; other site 663951008601 motif 1; other site 663951008602 motif 2; other site 663951008603 motif 3; other site 663951008604 ThrRS Threonyl-anticodon binding domain. ThrRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: ThrRS_anticodon; cd00860 663951008605 anticodon binding site; other site 663951008606 HMMPfam hit to PF03129, HGTP_anticodon, score 1.3e-31 663951008607 PS00339 Aminoacyl-transfer RNA synthetases class-II signature 2. 663951008608 HMMPfam hit to PF00587, tRNA-synt_2b, score 2.3e-59 663951008609 HMMPfam hit to PF07973, tRNA_SAD, score 4.6e-28 663951008610 HMMPfam hit to PF02824, TGS, score 1.5e-17 663951008611 primosomal protein DnaI; Reviewed; Region: PRK08939 663951008612 Primosomal protein DnaI N-terminus; Region: DnaI_N; pfam07319 663951008613 The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009 663951008614 Walker A motif; other site 663951008615 ATP binding site [chemical binding]; other site 663951008616 Walker B motif; other site 663951008617 PS00017 ATP/GTP-binding site motif A (P-loop). 663951008618 HMMPfam hit to PF07319, DnaI_N, score 4.7e-59 663951008619 Replication initiation/membrane attachment protein [DNA replication, recombination, and repair]; Region: DnaB; COG3611 663951008620 Replication initiation and membrane attachment; Region: DnaB_2; pfam07261 663951008621 HMMPfam hit to PF07261, DnaB_2, score 4e-304 663951008622 transcriptional regulator NrdR; Validated; Region: nrdR; PRK00464 663951008623 ATP cone domain; Region: ATP-cone; pfam03477 663951008624 HMMPfam hit to PF03477, ATP-cone, score 3.5e-36 663951008625 glyceraldehyde-3-phosphate dehydrogenase; Validated; Region: PRK07729 663951008626 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Region: Gp_dh_N; pfam00044 663951008627 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; pfam02800 663951008628 HMMPfam hit to PF02800, Gp_dh_C, score 3.8e-93 663951008629 PS00071 Glyceraldehyde 3-phosphate dehydrogenase active site. 663951008630 HMMPfam hit to PF00044, Gp_dh_N, score 1.1e-80 663951008631 Dephospho-CoA kinase [Coenzyme metabolism]; Region: CoaE; COG0237 663951008632 Dephospho-coenzyme A kinase (DPCK, EC 2.7.1.24) catalyzes the phosphorylation of dephosphocoenzyme A (dCoA) to yield CoA, which is the final step in CoA biosynthesis; Region: DPCK; cd02022 663951008633 CoA-binding site [chemical binding]; other site 663951008634 ATP-binding [chemical binding]; other site 663951008635 HMMPfam hit to PF01121, CoaE, score 9.3e-69 663951008636 PS00017 ATP/GTP-binding site motif A (P-loop). 663951008637 Formamidopyrimidine-DNA glycosylase [DNA replication, recombination, and repair]; Region: Nei; COG0266 663951008638 N-terminal domain of Escherichia coli Fpg1/MutM and related bacterial DNA glycosylases; Region: EcFpg-like_N; cd08966 663951008639 DNA binding site [nucleotide binding] 663951008640 catalytic residue [active] 663951008641 H2TH interface [polypeptide binding]; other site 663951008642 putative catalytic residues [active] 663951008643 turnover-facilitating residue; other site 663951008644 intercalation triad [nucleotide binding]; other site 663951008645 8OG recognition residue [nucleotide binding]; other site 663951008646 putative reading head residues; other site 663951008647 Formamidopyrimidine-DNA glycosylase H2TH domain; Region: H2TH; pfam06831 663951008648 Zinc finger found in FPG and IleRS; Region: zf-FPG_IleRS; pfam06827 663951008649 HMMPfam hit to PF06831, H2TH, score 7.9e-23 663951008650 HMMPfam hit to PF01149, Fapy_DNA_glyco, score 6.5e-48 663951008651 DNA polymerase I; Provisional; Region: PRK05755 663951008652 PIN domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: PIN_53EXO; cd09859 663951008653 active site 663951008654 metal binding site 1 [ion binding]; metal-binding site 663951008655 putative 5' ssDNA interaction site; other site 663951008656 metal binding site 3; metal-binding site 663951008657 metal binding site 2 [ion binding]; metal-binding site 663951008658 H3TH domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: H3TH_53EXO; cd09898 663951008659 putative DNA binding site [nucleotide binding]; other site 663951008660 putative metal binding site [ion binding]; other site 663951008661 inactive DEDDy 3'-5' exonuclease domain of Bacillus stearothermophilus DNA polymerase I and similar family-A DNA polymerases; Region: DNA_polA_I_Bacillus_like_exo; cd06140 663951008662 Polymerase I functions primarily to fill DNA gaps that arise during DNA repair, recombination and replication; Region: DNA_pol_A_pol_I_C; cd08637 663951008663 active site 663951008664 DNA binding site [nucleotide binding] 663951008665 catalytic site [active] 663951008666 HMMPfam hit to PF00476, DNA_pol_A, score 1.3e-192 663951008667 PS00447 DNA polymerase family A signature. 663951008668 HMMPfam hit to PF01367, 5_3_exonuc, score 3.3e-50 663951008669 HMMPfam hit to PF02739, 5_3_exonuc_N, score 1.4e-90 663951008670 13 probable transmembrane helices predicted for SATW20_16810 by TMHMM2.0 at aa 9-31, 63-85, 98-116,126-148, 153-170, 174-191, 198-215, 254-276, 289-311,321-343, 350-372, 377-392 and 404-426 663951008671 phosphate regulon sensor kinase PhoR; Region: phoR_proteo; TIGR02966 663951008672 Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082 663951008673 dimer interface [polypeptide binding]; other site 663951008674 phosphorylation site [posttranslational modification] 663951008675 Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075 663951008676 ATP binding site [chemical binding]; other site 663951008677 Mg2+ binding site [ion binding]; other site 663951008678 G-X-G motif; other site 663951008679 HMMPfam hit to PF02518, HATPase_c, score 5.1e-43 663951008680 HMMPfam hit to PF00512, HisKA, score 2.5e-22 663951008681 HMMPfam hit to PF00989, PAS, score 5.1e-07 663951008682 HMMPfam hit to PF00672, HAMP, score 2e-06 663951008683 2 probable transmembrane helices predicted for SATW20_16820 by TMHMM2.0 at aa 4-26 and 120-142 663951008684 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745 663951008685 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 663951008686 active site 663951008687 phosphorylation site [posttranslational modification] 663951008688 intermolecular recognition site; other site 663951008689 dimerization interface [polypeptide binding]; other site 663951008690 Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383 663951008691 DNA binding site [nucleotide binding] 663951008692 HMMPfam hit to PF00486, Trans_reg_C, score 2e-28 663951008693 HMMPfam hit to PF00072, Response_reg, score 5.8e-43 663951008694 isocitrate dehydrogenase; Reviewed; Region: PRK07006 663951008695 isocitrate dehydrogenase; Validated; Region: PRK07362 663951008696 HMMPfam hit to PF00180, Iso_dh, score 3.5e-169 663951008697 PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 663951008698 Bacillus subtilis (Bs) citrate synthase (CS)-II_like. CS catalyzes the condensation of acetyl coenzyme A (AcCoA) and oxalacetate (OAA) to form citrate and coenzyme A (CoA), the first step in the citric acid cycle (TCA or Krebs cycle). 2MCS catalyzes the...; Region: BSuCS-II_like; cd06110 663951008699 dimer interface [polypeptide binding]; other site 663951008700 Citrate synthase; Region: Citrate_synt; pfam00285 663951008701 active site 663951008702 citrylCoA binding site [chemical binding]; other site 663951008703 oxalacetate/citrate binding site [chemical binding]; other site 663951008704 coenzyme A binding site [chemical binding]; other site 663951008705 catalytic triad [active] 663951008706 HMMPfam hit to PF00285, Citrate_synt, score 2.4e-155 663951008707 PS00480 Citrate synthase signature. 663951008708 Gamma-aminobutyrate permease and related permeases [Amino acid transport and metabolism]; Region: AnsP; COG1113 663951008709 HMMPfam hit to PF00324, AA_permease, score 8e-123 663951008710 12 probable transmembrane helices predicted for SATW20_16860 by TMHMM2.0 at aa 13-35, 39-61, 80-102,122-144, 151-173, 198-220, 233-255, 270-292, 327-349,359-381, 402-421 and 426-444 663951008711 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 663951008712 CDS contains a frameshift after codon 268. Frameshift occurs due to a 5bp insertion 663951008713 HMMPfam hit to PF01609, Transposase_11, score 1.3e-10 663951008714 pyruvate kinase; Provisional; Region: PRK06354 663951008715 Pyruvate kinase (PK): Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low...; Region: Pyruvate_Kinase; cl17342 663951008716 domain interfaces; other site 663951008717 active site 663951008718 Phosphohistidine swiveling domain [Signal transduction mechanisms]; Region: COG3848 663951008719 HMMPfam hit to PF00391, PEP-utilizers, score 1.4e-12 663951008720 HMMPfam hit to PF02887, PK_C, score 1.3e-44 663951008721 HMMPfam hit to PF00224, PK, score 1.9e-222 663951008722 6-phosphofructokinase; Provisional; Region: PRK03202 663951008723 6-phosphofructokinase; Region: PFKA_ATP; TIGR02482 663951008724 active site 663951008725 ADP/pyrophosphate binding site [chemical binding]; other site 663951008726 dimerization interface [polypeptide binding]; other site 663951008727 allosteric effector site; other site 663951008728 fructose-1,6-bisphosphate binding site; other site 663951008729 HMMPfam hit to PF00365, PFK, score 2.6e-165 663951008730 PS00433 Phosphofructokinase signature. 663951008731 acetyl-CoA carboxylase carboxyltransferase subunit alpha; Validated; Region: PRK05724 663951008732 acetyl-CoA carboxylase carboxyltransferase alpha subunit; Provisional; Region: accA; CHL00198 663951008733 HMMPfam hit to PF03255, ACCA, score 3.4e-87 663951008734 acetyl-CoA carboxylase subunit beta; Validated; Region: PRK05654 663951008735 malonate decarboxylase subunit beta; Reviewed; Region: PRK07189; cl17682 663951008736 HMMPfam hit to PF01039, Carboxyl_trans, score 8.4e-12 663951008737 Malic enzyme [Energy production and conversion]; Region: SfcA; COG0281 663951008738 Malic enzyme, N-terminal domain; Region: malic; pfam00390 663951008739 NAD(P) binding domain of malic enzyme (ME), subgroup 2; Region: NAD_bind_2_malic_enz; cd05311 663951008740 putative NAD(P) binding site [chemical binding]; other site 663951008741 HMMPfam hit to PF03949, Malic_M, score 2.3e-129 663951008742 PS00331 Malic enzymes signature. 663951008743 HMMPfam hit to PF00390, malic, score 6.8e-75 663951008744 DNA polymerase III, alpha subunit [DNA replication, recombination, and repair]; Region: DnaE; COG0587 663951008745 Polymerase and Histidinol Phosphatase domain of alpha-subunit of bacterial polymerase III; Region: PHP_PolIIIA; cd07431 663951008746 active site 663951008747 PHP Thumb interface [polypeptide binding]; other site 663951008748 DnaE_OBF: A subfamily of OB folds corresponding to the C-terminal OB-fold nucleic acid binding domain of Thermus aquaticus and Escherichia coli type C replicative DNA polymerase III alpha subunit (DnaE). The DNA polymerase holoenzyme of E. coli contains...; Region: DnaE_OBF; cd04485 663951008749 generic binding surface I; other site 663951008750 generic binding surface II; other site 663951008751 HMMPfam hit to PF01336, tRNA_anti, score 5e-09 663951008752 PS00017 ATP/GTP-binding site motif A (P-loop). 663951008753 HMMPfam hit to PF07733, DNA_pol3_alpha, score 1.9e-262 663951008754 HMMPfam hit to PF02811, PHP, score 1.2e-14 663951008755 Exopolyphosphatase-related proteins [General function prediction only]; Region: COG0618 663951008756 DHH family; Region: DHH; pfam01368 663951008757 DHHA1 domain; Region: DHHA1; pfam02272 663951008758 HMMPfam hit to PF02272, DHHA1, score 1.3e-11 663951008759 PS00126 3'5'-cyclic nucleotide phosphodiesterases signature. 663951008760 HMMPfam hit to PF01368, DHH, score 8.8e-44 663951008761 Predicted transcriptional regulator containing CBS domains [Transcription]; Region: COG4109 663951008762 Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cl17414 663951008763 DNA-binding site [nucleotide binding]; DNA binding site 663951008764 DRTGG domain; Region: DRTGG; pfam07085 663951008765 This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with a DRTGG domain upstream. The function of the DRTGG domain, named after its conserved residues, is unknown. CBS is a small domain originally...; Region: CBS_pair_DRTGG_assoc; cd04596 663951008766 The hotdog fold was initially identified in the E. coli FabA (beta-hydroxydecanoyl-acyl carrier protein (ACP)-dehydratase) structure and subsequently in 4HBT (4-hydroxybenzoyl-CoA thioesterase) from Pseudomonas. A number of other seemingly unrelated...; Region: hot_dog; cd03440 663951008767 active site 2 [active] 663951008768 active site 1 [active] 663951008769 HMMPfam hit to PF00571, CBS, score 1.6e-22 663951008770 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 663951008771 HMMPfam hit to PF07085, DRTGG, score 3.9e-53 663951008772 PS00339 Aminoacyl-transfer RNA synthetases class-II signature 2. 663951008773 Predicted helix-turn-helix motif with score 1841.000, SD 5.46 at aa 20-41, sequence ISVRKIAKFLNVSEGTAYRAIK 663951008774 Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293 663951008775 Ligand Binding Site [chemical binding]; other site 663951008776 HMMPfam hit to PF00582, Usp, score 1.4e-17 663951008777 Predicted Zn-dependent hydrolases of the beta-lactamase fold [General function prediction only]; Region: COG2220 663951008778 metal-dependent hydrolase; Provisional; Region: PRK00685 663951008779 HMMPfam hit to PF00753, Lactamase_B, score 1.1e-22 663951008780 Xaa-Pro aminopeptidase [Amino acid transport and metabolism]; Region: PepP; COG0006 663951008781 Creatinase/Prolidase N-terminal domain; Region: Creatinase_N; pfam01321 663951008782 Similar to Prolidase and Aminopeptidase P. The members of this subfamily presumably catalyse hydrolysis of Xaa-Pro dipeptides and/or release of any N-terminal amino acid, including proline, that is linked with proline; Region: APP-like; cd01092 663951008783 active site 663951008784 HMMPfam hit to PF01321, Creatinase_N, score 4.7e-13 663951008785 HMMPfam hit to PF00557, Peptidase_M24, score 1.3e-70 663951008786 Alanine dehydrogenase [Amino acid transport and metabolism]; Region: Ald; COG0686 663951008787 Alanine dehydrogenase NAD-binding and catalytic domains; Region: L-AlaDH; cd05305 663951008788 hexamer interface [polypeptide binding]; other site 663951008789 ligand binding site [chemical binding]; other site 663951008790 putative active site [active] 663951008791 NAD(P) binding site [chemical binding]; other site 663951008792 HMMPfam hit to PF01262, AlaDh_PNT_C, score 2.4e-94 663951008793 PS00837 Alanine dehydrogenase & pyridine nucleotide transhydrogenase signature 2. 663951008794 HMMPfam hit to PF05222, AlaDh_PNT_N, score 3.2e-82 663951008795 Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293 663951008796 Ligand Binding Site [chemical binding]; other site 663951008797 HMMPfam hit to PF00582, Usp, score 4.6e-22 663951008798 acetate kinase A/propionate kinase 2; Reviewed; Region: PRK00180 663951008799 propionate/acetate kinase; Provisional; Region: PRK12379 663951008800 HMMPfam hit to PF00871, Acetate_kinase, score 1.2e-231 663951008801 PS00017 ATP/GTP-binding site motif A (P-loop). 663951008802 PS01076 Acetate and butyrate kinases family signature 2. 663951008803 PS00430 TonB-dependent receptor proteins signature 1. 663951008804 PS01075 Acetate and butyrate kinases family signature 1. 663951008805 Adenine-specific DNA methylase [DNA replication, recombination, and repair]; Region: COG0827 663951008806 S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440 663951008807 S-adenosylmethionine binding site [chemical binding]; other site 663951008808 Peroxiredoxin (PRX) family, Atypical 2-cys PRX subfamily; composed of PRXs containing peroxidatic and resolving cysteines, similar to the homodimeric thiol specific antioxidant (TSA) protein also known as TRX-dependent thiol peroxidase (Tpx). Tpx is a...; Region: PRX_Atyp2cys; cd03014 663951008809 dimer interface [polypeptide binding]; other site 663951008810 catalytic triad [active] 663951008811 peroxidatic and resolving cysteines [active] 663951008812 HMMPfam hit to PF08534, Redoxin, score 3.2e-37 663951008813 PS01265 Tpx family signature. 663951008814 hypothetical protein; Provisional; Region: PRK10621 663951008815 Sulfite exporter TauE/SafE; Region: TauE; pfam01925 663951008816 HMMPfam hit to PF01925, DUF81, score 5.1e-26 663951008817 7 probable transmembrane helices predicted for SATW20_17050 by TMHMM2.0 at aa 5-27, 73-95, 100-119,132-154, 159-178, 191-213 and 223-245 663951008818 PS00061 Short-chain dehydrogenases/reductases family signature. 663951008819 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 663951008820 thiamine biosynthesis protein ThiI; Provisional; Region: PRK01565 663951008821 THUMP domain of thiamine biosynthesis protein ThiI; Region: THUMP_ThiI; cd11716 663951008822 ThiI is required for thiazole synthesis in the thiamine biosynthesis pathway. It belongs to the Adenosine Nucleotide Hydrolysis suoerfamily and predicted to bind to Adenosine nucleotide; Region: ThiI; cd01712 663951008823 Ligand Binding Site [chemical binding]; other site 663951008824 HMMPfam hit to PF02568, ThiI, score 1.4e-89 663951008825 HMMPfam hit to PF02926, THUMP, score 2.8e-17 663951008826 cysteine desulfurase NifS; Region: FeS_nifS; TIGR03402 663951008827 Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes [Amino acid transport and metabolism]; Region: NifS; COG1104 663951008828 pyridoxal 5'-phosphate binding pocket [chemical binding]; other site 663951008829 catalytic residue [active] 663951008830 HMMPfam hit to PF00266, Aminotran_5, score 4e-69 663951008831 Negative regulator of septation ring formation [Cell division and chromosome partitioning]; Region: EzrA; COG4477 663951008832 HMMPfam hit to PF06160, EzrA, score 1.2e-296 663951008833 1 probable transmembrane helix predicted for SATW20_17080 by TMHMM2.0 at aa 2-24 663951008834 GAF domain-containing protein [Signal transduction mechanisms]; Region: COG1956 663951008835 GAF domain; Region: GAF_2; pfam13185 663951008836 HMMPfam hit to PF01590, GAF, score 1.4e-06 663951008837 PS01320 Uncharacterized protein family UPF0067 signature. 663951008838 30S ribosomal protein S4; Validated; Region: rpsD; PRK05327 663951008839 Ribosomal protein S4/S9 N-terminal domain; Region: Ribosomal_S4; pfam00163 663951008840 S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site; Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165 663951008841 RNA binding surface [nucleotide binding]; other site 663951008842 HMMPfam hit to PF00163, Ribosomal_S4, score 3.3e-29 663951008843 HMMPfam hit to PF01479, S4, score 1.5e-22 663951008844 Glycerophosphoryl diester phosphodiesterase [Energy production and conversion]; Region: UgpQ; COG0584 663951008845 Catalytic domain of phosphoinositide-specific phospholipase C-like phosphodiesterases superfamily; Region: PI-PLCc_GDPD_SF; cl14615 663951008846 active site 663951008847 catalytic site [active] 663951008848 HMMPfam hit to PF03009, GDPD, score 1e-46 663951008849 OsmC-like protein; Region: OsmC; cl00767 663951008850 HMMPfam hit to PF02566, OsmC, score 8.7e-24 663951008851 Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase [Amino acid transport and metabolism]; Region: COG0075 663951008852 pyridoxal 5'-phosphate binding pocket [chemical binding]; other site 663951008853 catalytic residue [active] 663951008854 HMMPfam hit to PF00266, Aminotran_5, score 1.7e-14 663951008855 PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 663951008856 D-3-phosphoglycerate dehydrogenase; Region: PGDH; TIGR01327 663951008857 Phosphoglycerate dehydrogenases, NAD-binding and catalytic domains; Region: PGDH_4; cd12173 663951008858 ligand binding site [chemical binding]; other site 663951008859 NAD binding site [chemical binding]; other site 663951008860 dimerization interface [polypeptide binding]; other site 663951008861 catalytic site [active] 663951008862 C-terminal ACT (regulatory) domain of D-3-phosphoglycerate dehydrogenase (3PGDH); Region: ACT_3PGDH-xct; cd04902 663951008863 putative L-serine binding site [chemical binding]; other site 663951008864 HMMPfam hit to PF00389, 2-Hacid_dh, score 1.6e-37 663951008865 HMMPfam hit to PF02826, 2-Hacid_dh_C, score 7e-86 663951008866 PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 663951008867 HMMPfam hit to PF01842, ACT, score 2.6e-09 663951008868 Haloacid dehalogenase-like hydrolase; Region: HAD_2; pfam13419 663951008869 Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427 663951008870 motif II; other site 663951008871 PTS system, N-acetylglucosamine-specific IIBC component; Region: PTS-II-BC-nag; TIGR01998 663951008872 Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263 663951008873 PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212 663951008874 active site turn [active] 663951008875 phosphorylation site [posttranslational modification] 663951008876 HMMPfam hit to PF00367, PTS_EIIB, score 2.2e-15 663951008877 PS01035 PTS EIIB domains cysteine phosphorylation site signature. 663951008878 11 probable transmembrane helices predicted for SATW20_17160 by TMHMM2.0 at aa 15-37, 44-66, 76-93,114-133, 153-175, 187-206, 241-263, 276-293, 298-320,325-342 and 352-374 663951008879 HMMPfam hit to PF02378, PTS_EIIC, score 2e-73 663951008880 1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid metabolism]; Region: PlsC; COG0204 663951008881 Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989 663951008882 putative acyl-acceptor binding pocket; other site 663951008883 HMMPfam hit to PF01553, Acyltransferase, score 1.3e-23 663951008884 Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365 663951008885 PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987 663951008886 protein binding site [polypeptide binding]; other site 663951008887 1 probable transmembrane helix predicted for SATW20_17180 by TMHMM2.0 at aa 27-49 663951008888 HMMPfam hit to PF00089, Trypsin, score 6.1e-21 663951008889 tyrosyl-tRNA synthetase; Validated; Region: PRK05912 663951008890 catalytic core domain of tyrosinyl-tRNA and tryptophanyl-tRNA synthetase; Region: Tyr_Trp_RS_core; cd00395 663951008891 active site 663951008892 HIGH motif; other site 663951008893 dimer interface [polypeptide binding]; other site 663951008894 KMSKS motif; other site 663951008895 S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site; Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165 663951008896 RNA binding surface [nucleotide binding]; other site 663951008897 HMMPfam hit to PF01479, S4, score 1.3e-08 663951008898 HMMPfam hit to PF00579, tRNA-synt_1b, score 2.1e-116 663951008899 PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 663951008900 Membrane carboxypeptidase (penicillin-binding protein) [Cell envelope biogenesis, outer membrane]; Region: MrcB; COG0744 663951008901 Transglycosylase; Region: Transgly; pfam00912 663951008902 1 probable transmembrane helix predicted for SATW20_17200 by TMHMM2.0 at aa 27-49 663951008903 HMMPfam hit to PF00912, Transgly, score 1.8e-71 663951008904 haptoglobin-binding heme uptake protein HarA; Region: IsdH_HarA; TIGR03658 663951008905 Gram-positive signal peptide, YSIRK family; Region: YSIRK_signal; TIGR01168 663951008906 NEAr Transporter domain; Region: NEAT; smart00725 663951008907 NEAr Transporter domain; Region: NEAT; smart00725 663951008908 NEAr Transport domain, a component of cell surface proteins; Region: NEAT; cd06920 663951008909 heme-binding site [chemical binding]; other site 663951008910 PS00343 Gram-positive cocci surface proteins 'anchoring' hexapeptide. 663951008911 HMMPfam hit to PF05031, NEAT, score 3.4e-37 663951008912 HMMPfam hit to PF05031, NEAT, score 1.9e-35 663951008913 HMMPfam hit to PF05031, NEAT, score 4.8e-27 663951008914 HMMPfam hit to PF04650, YSIRK_signal, score 3.7e-08 663951008915 formate--tetrahydrofolate ligase; Provisional; Region: PRK13505 663951008916 Formyltetrahydrofolate synthetase (FTHFS) catalyzes the ATP-dependent activation of formate ion via its addition to the N10 position of tetrahydrofolate. FTHFS is a highly expressed key enzyme in both the Wood-Ljungdahl pathway of autotrophic CO2...; Region: FTHFS; cd00477 663951008917 Potassium binding sites [ion binding]; other site 663951008918 Cesium cation binding sites [ion binding]; other site 663951008919 HMMPfam hit to PF01268, FTHFS, score 0 663951008920 PS00722 Formate--tetrahydrofolate ligase signature 2. 663951008921 acetyl-CoA synthetase; Provisional; Region: PRK04319 663951008922 Domain of unknown function (DUF3448); Region: DUF3448; pfam11930 663951008923 Uncharacterized subfamily of Acetyl-CoA synthetase like family (ACS); Region: MACS_like_4; cd05969 663951008924 active site 663951008925 acyl-activating enzyme (AAE) consensus motif; other site 663951008926 putative CoA binding site [chemical binding]; other site 663951008927 AMP binding site [chemical binding]; other site 663951008928 HMMPfam hit to PF00501, AMP-binding, score 1.1e-127 663951008929 PS00455 Putative AMP-binding domain signature. 663951008930 1 probable transmembrane helix predicted for SATW20_17230 by TMHMM2.0 at aa 112-134 663951008931 Deacetylases, including yeast histone deacetylase and acetoin utilization protein [Chromatin structure and dynamics / Secondary metabolites biosynthesis, transport, and catabolism]; Region: AcuC; COG0123 663951008932 Class I histone deacetylase AcuC (Acetoin utilization protein)-like enzymes; Region: HDAC_AcuC_like; cd09994 663951008933 active site 663951008934 Zn binding site [ion binding]; other site 663951008935 HMMPfam hit to PF00850, Hist_deacetyl, score 4.7e-136 663951008936 catabolite control protein A; Region: ccpA; TIGR01481 663951008937 Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392 663951008938 DNA binding site [nucleotide binding] 663951008939 domain linker motif; other site 663951008940 Ligand-binding domain of the catabolite control protein A (CcpA), which functions as the major transcriptional regulator of carbon catabolite repression/regulation; Region: PBP1_CcpA_like; cd06298 663951008941 dimerization interface [polypeptide binding]; other site 663951008942 effector binding site; other site 663951008943 HMMPfam hit to PF00532, Peripla_BP_1, score 1.6e-06 663951008944 HMMPfam hit to PF00356, LacI, score 6.5e-13 663951008945 Predicted helix-turn-helix motif with score 1741.000, SD 5.12 at aa 3-24, sequence VTIYDVAREARVSMATVSRVVN 663951008946 PS00356 Bacterial regulatory proteins, lacI family signature. 663951008947 bifunctional 3-deoxy-7-phosphoheptulonate synthase/chorismate mutase; Reviewed; Region: PRK12595 663951008948 Chorismate mutase type II; Region: CM_2; cl00693 663951008949 phospho-2-dehydro-3-deoxyheptonate aldolase; Region: DAHP_synth_Bsub; TIGR01361 663951008950 HMMPfam hit to PF00793, DAHP_synth_1, score 1.9e-125 663951008951 HMMPfam hit to PF01817, CM_2, score 5.2e-32 663951008952 1 probable transmembrane helix predicted for SATW20_17280 by TMHMM2.0 at aa 28-45 663951008953 Uncharacterized protein containing a divergent version of the methyl-accepting chemotaxis-like domain [General function prediction only]; Region: COG4768 663951008954 HMMPfam hit to PF06103, DUF948, score 1.1e-50 663951008955 1 probable transmembrane helix predicted for SATW20_17290 by TMHMM2.0 at aa 4-26 663951008956 UDP-N-acetylmuramate--L-alanine ligase; Provisional; Region: murC; PRK00421 663951008957 Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225 663951008958 Mur ligase middle domain; Region: Mur_ligase_M; pfam08245 663951008959 Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875 663951008960 HMMPfam hit to PF02875, Mur_ligase_C, score 2e-27 663951008961 HMMPfam hit to PF08245, Mur_ligase_M, score 8.4e-42 663951008962 HMMPfam hit to PF01225, Mur_ligase, score 4.4e-31 663951008963 DNA segregation ATPase FtsK/SpoIIIE and related proteins [Cell division and chromosome partitioning]; Region: FtsK; COG1674 663951008964 FtsK/SpoIIIE family; Region: FtsK_SpoIIIE; pfam01580 663951008965 This domain directs oriented DNA translocation and forms a winged helix structure; Region: Ftsk_gamma; smart00843 663951008966 HMMPfam hit to PF01580, FtsK_SpoIIIE, score 3.4e-79 663951008967 PS00017 ATP/GTP-binding site motif A (P-loop). 663951008968 tRNA-binding-domain-containing prokaryotic phenylalanly tRNA synthetase (PheRS) beta chain. PheRS aminoacylate phenylalanine transfer RNAs (tRNAphe). PheRSs belong structurally to class II aminoacyl tRNA synthetases (aaRSs) but, as they aminoacylate...; Region: tRNA_bind_bactPheRS; cd02796 663951008969 putative tRNA-binding site [nucleotide binding]; other site 663951008970 HMMPfam hit to PF01588, tRNA_bind, score 1.6e-32 663951008971 PS00225 Crystallins beta and gamma 'Greek key' motif signature. 663951008972 hypothetical protein; Provisional; Region: PRK13668 663951008973 HMMPfam hit to PF07285, DUF1444, score 7.6e-215 663951008974 TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947 663951008975 Thioredoxin-like; Region: Thioredoxin_8; pfam13905 663951008976 catalytic residues [active] 663951008977 HMMPfam hit to PF00085, Thioredoxin, score 5e-09 663951008978 Cellulase M and related proteins [Carbohydrate transport and metabolism]; Region: FrvX; COG1363 663951008979 M42 Peptidase, Endoglucanases; Region: M42_Frv; cd05656 663951008980 oligomer interface [polypeptide binding]; other site 663951008981 active site 663951008982 metal binding site [ion binding]; metal-binding site 663951008983 HMMPfam hit to PF05343, Peptidase_M42, score 6.9e-143 663951008984 Predicted small secreted protein [Function unknown]; Region: COG5584 663951008985 1 probable transmembrane helix predicted for SATW20_17360 by TMHMM2.0 at aa 7-29 663951008986 HMMPfam hit to PF03413, PepSY, score 7.1e-05 663951008987 Zn-dependent hydrolases, including glyoxylases [General function prediction only]; Region: GloB; COG0491 663951008988 HMMPfam hit to PF00753, Lactamase_B, score 1.6e-15 663951008989 S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440 663951008990 S-adenosylmethionine binding site [chemical binding]; other site 663951008991 HMMPfam hit to PF02390, Methyltransf_4, score 1.9e-58 663951008992 Phosphotransferase enzyme family; Region: APH; pfam01636 663951008993 Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs)...; Region: APH_ChoK_like; cd05120 663951008994 active site 663951008995 substrate binding site [chemical binding]; other site 663951008996 ATP binding site [chemical binding]; other site 663951008997 HMMPfam hit to PF01636, APH, score 3.9e-38 663951008998 Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase [Amino acid transport and metabolism / Coenzyme metabolism]; Region: IlvE; COG0115 663951008999 D-Alanine aminotransferase (D-AAT_like): D-amino acid aminotransferase catalyzes transamination between D-amino acids and their respective alpha-keto acids. It plays a major role in the synthesis of bacterial cell wall components like D-alanine and...; Region: D-AAT_like; cd01558 663951009000 homodimer interface [polypeptide binding]; other site 663951009001 substrate-cofactor binding pocket; other site 663951009002 pyridoxal 5'-phosphate binding site [chemical binding]; other site 663951009003 catalytic residue [active] 663951009004 HMMPfam hit to PF01063, Aminotran_4, score 1e-118 663951009005 PS00770 Aminotransferases class-IV signature. 663951009006 dipeptidase PepV; Reviewed; Region: PRK07318 663951009007 M20 Peptidase Xaa-His dipeptidase (PepV) degrades hydrophobic dipeptides; Region: M20_PepV; cd03888 663951009008 active site 663951009009 metal binding site [ion binding]; metal-binding site 663951009010 HMMPfam hit to PF01546, Peptidase_M20, score 4.1e-20 663951009011 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases [Translation, ribosomal structure and biogenesis]; Region: RsuA; COG1187 663951009012 S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site; Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165 663951009013 RNA binding surface [nucleotide binding]; other site 663951009014 Pseudouridine synthase, Escherichia coli RsuA like; Region: PseudoU_synth_RsuA; cd02553 663951009015 active site 663951009016 uracil binding [chemical binding]; other site 663951009017 HMMPfam hit to PF00849, PseudoU_synth_2, score 1.5e-15 663951009018 PS01149 Rsu family of pseudouridine synthase signature. 663951009019 HMMPfam hit to PF01479, S4, score 3.2e-12 663951009020 Membrane protein involved in the export of O-antigen and teichoic acid [General function prediction only]; Region: RfbX; COG2244 663951009021 Stage V sporulation protein B, also known as Stage III sporulation protein F, and related proteins; Region: MATE_SpoVB_like; cd13124 663951009022 14 probable transmembrane helices predicted for SATW20_17440 by TMHMM2.0 at aa 12-34, 49-71, 91-113,133-155, 176-198, 202-221, 250-267, 303-322, 342-364,388-410, 417-439, 443-462, 475-497 and 507-529 663951009023 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 663951009024 HMMPfam hit to PF01943, Polysacc_synt, score 1.3e-13 663951009025 HI0933-like protein; Region: HI0933_like; pfam03486 663951009026 HMMPfam hit to PF03486, HI0933_like, score 3.2e-230 663951009027 YSIRK type signal peptide; Region: YSIRK_signal; pfam04650 663951009028 SasC/Mrp/FmtB intercellular aggregation domain; Region: SasC_Mrp_aggreg; TIGR04263 663951009029 Domain of Unknown Function (DUF1542); Region: DUF1542; pfam07564 663951009030 Domain of Unknown Function (DUF1542); Region: DUF1542; pfam07564 663951009031 Domain of Unknown Function (DUF1542); Region: DUF1542; pfam07564 663951009032 Domain of Unknown Function (DUF1542); Region: DUF1542; pfam07564 663951009033 Domain of Unknown Function (DUF1542); Region: DUF1542; pfam07564 663951009034 Domain of Unknown Function (DUF1542); Region: DUF1542; pfam07564 663951009035 Domain of Unknown Function (DUF1542); Region: DUF1542; pfam07564 663951009036 Domain of Unknown Function (DUF1542); Region: DUF1542; pfam07564 663951009037 Domain of Unknown Function (DUF1542); Region: DUF1542; pfam07564 663951009038 Domain of Unknown Function (DUF1542); Region: DUF1542; pfam07564 663951009039 Domain of Unknown Function (DUF1542); Region: DUF1542; pfam07564 663951009040 Domain of Unknown Function (DUF1542); Region: DUF1542; pfam07564 663951009041 Domain of Unknown Function (DUF1542); Region: DUF1542; pfam07564 663951009042 Domain of Unknown Function (DUF1542); Region: DUF1542; pfam07564 663951009043 Domain of Unknown Function (DUF1542); Region: DUF1542; pfam07564 663951009044 PS00343 Gram-positive cocci surface proteins 'anchoring' hexapeptide. 663951009045 HMMPfam hit to PF07564, DUF1542, score 1.2e-16 663951009046 HMMPfam hit to PF07564, DUF1542, score 1.2e-14 663951009047 HMMPfam hit to PF07564, DUF1542, score 7.4e-15 663951009048 HMMPfam hit to PF07564, DUF1542, score 5.1e-16 663951009049 HMMPfam hit to PF07564, DUF1542, score 6.1e-16 663951009050 HMMPfam hit to PF07564, DUF1542, score 5.9e-15 663951009051 HMMPfam hit to PF07564, DUF1542, score 1.3e-18 663951009052 HMMPfam hit to PF07564, DUF1542, score 8e-15 663951009053 HMMPfam hit to PF07564, DUF1542, score 2.5e-19 663951009054 HMMPfam hit to PF07564, DUF1542, score 8.2e-16 663951009055 HMMPfam hit to PF07564, DUF1542, score 3.9e-22 663951009056 HMMPfam hit to PF07564, DUF1542, score 1.6e-18 663951009057 HMMPfam hit to PF07564, DUF1542, score 1.1e-13 663951009058 HMMPfam hit to PF07564, DUF1542, score 2.5e-18 663951009059 HMMPfam hit to PF07564, DUF1542, score 2.5e-19 663951009060 HMMPfam hit to PF07564, DUF1542, score 8.8e-19 663951009061 HMMPfam hit to PF07564, DUF1542, score 1.2e-20 663951009062 HMMPfam hit to PF07554, FIVAR, score 3.3e-06 663951009063 HMMPfam hit to PF04650, YSIRK_signal, score 1.5e-10 663951009064 Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158 663951009065 active site residue [active] 663951009066 HMMPfam hit to PF00581, Rhodanese, score 2e-08 663951009067 leucyl-tRNA synthetase; Validated; Region: leuS; PRK00390 663951009068 catalytic core domain of leucyl-tRNA synthetases; Region: LeuRS_core; cd00812 663951009069 HIGH motif; other site 663951009070 Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603 663951009071 catalytic core domain of leucyl-tRNA synthetases; Region: LeuRS_core; cd00812 663951009072 active site 663951009073 KMSKS motif; other site 663951009074 Anticodon-binding domain of bacterial and eukaryotic mitochondrial leucyl tRNA synthetases; Region: Anticodon_Ia_Leu_BEm; cd07958 663951009075 tRNA binding surface [nucleotide binding]; other site 663951009076 HMMPfam hit to PF08264, Anticodon_1, score 7.7e-17 663951009077 HMMPfam hit to PF00133, tRNA-synt_1, score 2.7e-15 663951009078 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 663951009079 PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 663951009080 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 663951009081 Major Facilitator Superfamily; Region: MFS_1; pfam07690 663951009082 putative substrate translocation pore; other site 663951009083 12 probable transmembrane helices predicted for SATW20_17490 by TMHMM2.0 at aa 7-25, 40-62, 69-91, 96-118,131-153, 159-181, 202-224, 244-266, 275-292, 297-319,332-354 and 364-381 663951009084 HMMPfam hit to PF07690, MFS_1, score 2.6e-62 663951009085 Predicted Fe-S oxidoreductase [General function prediction only]; Region: COG1242 663951009086 HMMPfam hit to PF04055, Radical_SAM, score 4.2e-13 663951009087 S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440 663951009088 S-adenosylmethionine binding site [chemical binding]; other site 663951009089 PS00430 TonB-dependent receptor proteins signature 1. 663951009090 HMMPfam hit to PF06962, rRNA_methylase, score 7.6e-91 663951009091 staphylococcal accessory regulator family; Region: Staph_reg_Sar; TIGR01889 663951009092 HMMPfam hit to PF01047, MarR, score 1e-06 663951009093 Transposase, Mutator family; Region: Transposase_mut; pfam00872 663951009094 MULE transposase domain; Region: MULE; pfam10551 663951009095 HMMPfam hit to PF00872, Transposase_mut, score 9.8e-228 663951009096 PS01007 Transposases, Mutator family, signature. 663951009097 CDS contains a frameshift after codon 153 663951009098 Lysophospholipase [Lipid metabolism]; Region: PldB; COG2267 663951009099 Putative lysophospholipase; Region: Hydrolase_4; pfam12146 663951009100 HMMPfam hit to PF00561, Abhydrolase_1, score 1.7e-06 663951009101 Proline dehydrogenase [Amino acid transport and metabolism]; Region: PutA; COG0506 663951009102 HMMPfam hit to PF01619, Pro_dh, score 6.4e-59 663951009103 1 probable transmembrane helix predicted for SATW20_17570 by TMHMM2.0 at aa 310-327 663951009104 lumazine synthase (6,7-dimethyl-8-ribityllumazine synthase, LS), catalyzes the penultimate step in the biosynthesis of riboflavin (vitamin B2); type-I; Region: Lumazine_synthase-I; cd09209 663951009105 homopentamer interface [polypeptide binding]; other site 663951009106 active site 663951009107 HMMPfam hit to PF00885, DMRL_synthase, score 8.9e-85 663951009108 bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II protein; Provisional; Region: PRK09311 663951009109 3,4-dihydroxy-2-butanone 4-phosphate synthase; Region: DHBP_synthase; pfam00926 663951009110 GTP cyclohydrolase II (RibA). GTP cyclohydrolase II catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5' phosphate, formate, pyrophosphate (APy), and GMP in the biosynthetic pathway of riboflavin. Riboflavin is the...; Region: GTP_cyclohydro2; cd00641 663951009111 dimerization interface [polypeptide binding]; other site 663951009112 active site 663951009113 HMMPfam hit to PF00925, GTP_cyclohydro2, score 9.9e-79 663951009114 HMMPfam hit to PF00926, DHBP_synthase, score 1.8e-107 663951009115 riboflavin synthase subunit alpha; Provisional; Region: PRK09289 663951009116 Lumazine binding domain; Region: Lum_binding; pfam00677 663951009117 Lumazine binding domain; Region: Lum_binding; pfam00677 663951009118 HMMPfam hit to PF00677, Lum_binding, score 2.1e-23 663951009119 HMMPfam hit to PF00677, Lum_binding, score 4.2e-20 663951009120 PS00430 TonB-dependent receptor proteins signature 1. 663951009121 riboflavin biosynthesis protein RibD; Region: eubact_ribD; TIGR00326 663951009122 Riboflavin-specific deaminase. Riboflavin biosynthesis protein RibD (Diaminohydroxyphosphoribosylaminopyrimidine deaminase) catalyzes the deamination of 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate, which is an intermediate step in the...; Region: Riboflavin_deaminase-reductase; cd01284 663951009123 catalytic motif [active] 663951009124 Zn binding site [ion binding]; other site 663951009125 RibD C-terminal domain; Region: RibD_C; cl17279 663951009126 HMMPfam hit to PF01872, RibD_C, score 1.6e-37 663951009127 HMMPfam hit to PF00383, dCMP_cyt_deam_1, score 5.8e-31 663951009128 PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 663951009129 Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4529 663951009130 FAD-NAD(P)-binding; Region: NAD_binding_9; pfam13454 663951009131 Anion permease ArsB. These permeases have been shown to export arsenate and antimonite in eubacteria and archaea. A typical ArsB permease contains 8-13 transmembrane helices and can function either independently as a chemiosmotic transporter or as a...; Region: ArsB_permease; cd01118 663951009132 arsenical pump membrane protein; Provisional; Region: PRK15445 663951009133 transmembrane helices; other site 663951009134 11 probable transmembrane helices predicted for SATW20_17630 by TMHMM2.0 at aa 2-19, 24-46, 53-72, 98-120,141-163, 178-200, 221-243, 248-265, 285-307, 317-336 and 407-429 663951009135 HMMPfam hit to PF02040, ArsB, score 3.9e-292 663951009136 Low molecular weight phosphatase family; Region: LMWPc; cd00115 663951009137 Low molecular weight phosphotyrosine protein phosphatase; Region: LMWPc; pfam01451 663951009138 active site 663951009139 HMMPfam hit to PF01451, LMWPc, score 4.2e-51 663951009140 Beta- N-acetylglucosaminidase [Carbohydrate transport and metabolism]; Region: LytD; COG4193 663951009141 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase; Region: Glucosaminidase; cl17361 663951009142 HMMPfam hit to PF01832, Glucosaminidase, score 7.9e-36 663951009143 1 probable transmembrane helix predicted for SATW20_17650 by TMHMM2.0 at aa 7-29 663951009144 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog [Transcription]; Region: RpoE; COG1595 663951009145 Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171 663951009146 DNA binding residues [nucleotide binding] 663951009147 HMMPfam hit to PF04542, Sigma70_r2, score 0.00055 663951009148 HMMPfam hit to PF08281, Sigma70_r4_2, score 0.0001 663951009149 Predicted helix-turn-helix motif with score 1109.000, SD 2.96 at aa 150-171, sequence YKQFEIAEIMSLSLSTIKLIKM 663951009150 2 probable transmembrane helices predicted for SATW20_17690 by TMHMM2.0 at aa 67-89 and 109-128 663951009151 CAAX protease self-immunity; Region: Abi; pfam02517 663951009152 7 probable transmembrane helices predicted for SATW20_17700 by TMHMM2.0 at aa 17-39, 44-66, 73-95,115-134, 147-161, 166-185 and 192-210 663951009153 HMMPfam hit to PF02517, Abi, score 2.6e-19 663951009154 Transaldolase-like fructose-6-phosphate aldolases (FSA) found in bacteria and archaea; Region: Transaldolase_FSA; cd00956 663951009155 active site 663951009156 intersubunit interactions; other site 663951009157 catalytic residue [active] 663951009158 HMMPfam hit to PF00923, Transaldolase, score 5.3e-10 663951009159 3 probable transmembrane helices predicted for SATW20_17720 by TMHMM2.0 at aa 7-29, 34-56 and 77-99 663951009160 camphor resistance protein CrcB; Provisional; Region: PRK14201 663951009161 HMMPfam hit to PF02537, CRCB, score 1.3e-27 663951009162 4 probable transmembrane helices predicted for SATW20_17730 by TMHMM2.0 at aa 4-21, 33-55, 65-87 and 92-114 663951009163 Integral membrane protein possibly involved in chromosome condensation [Cell division and chromosome partitioning]; Region: CrcB; COG0239 663951009164 HMMPfam hit to PF02537, CRCB, score 3.5e-21 663951009165 4 probable transmembrane helices predicted for SATW20_17740 by TMHMM2.0 at aa 4-21, 33-54, 58-80 and 93-115 663951009166 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 663951009167 CDS contains a frameshift after codon 274, due to a deletion 663951009168 HMMPfam hit to PF01609, Transposase_11, score 0.026 663951009169 Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660 663951009170 Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248 663951009171 active site 663951009172 catalytic tetrad [active] 663951009173 HMMPfam hit to PF00248, Aldo_ket_red, score 3.6e-119 663951009174 PS00063 Aldo/keto reductase family putative active site signature. 663951009175 Predicted helix-turn-helix motif with score 1298.000, SD 3.61 at aa 202-223, sequence ETIKDIAQELGKSPAQVVLRWN 663951009176 PS00062 Aldo/keto reductase family signature 2. 663951009177 PS00798 Aldo/keto reductase family signature 1. 663951009178 1 probable transmembrane helix predicted for SATW20_17780 by TMHMM2.0 at aa 7-29 663951009179 S-adenosylmethionine synthetase; Validated; Region: PRK05250 663951009180 S-adenosylmethionine synthetase, N-terminal domain; Region: S-AdoMet_synt_N; pfam00438 663951009181 S-adenosylmethionine synthetase, central domain; Region: S-AdoMet_synt_M; pfam02772 663951009182 S-adenosylmethionine synthetase, C-terminal domain; Region: S-AdoMet_synt_C; pfam02773 663951009183 HMMPfam hit to PF02773, S-AdoMet_synt_C, score 1.9e-97 663951009184 PS00377 S-adenosylmethionine synthetase signature 2. 663951009185 HMMPfam hit to PF02772, S-AdoMet_synt_M, score 3.3e-88 663951009186 PS00376 S-adenosylmethionine synthetase signature 1. 663951009187 HMMPfam hit to PF00438, S-AdoMet_synt_N, score 8.3e-61 663951009188 Phosphoenolpyruvate carboxykinase (PEPCK), a critical gluconeogenic enzyme, catalyzes the first committed step in the diversion of tricarboxylic acid cycle intermediates toward gluconeogenesis. It catalyzes the reversible decarboxylation and...; Region: PEPCK_ATP; cd00484 663951009189 Phosphoenolpyruvate carboxykinase; Region: PEPCK_ATP; pfam01293 663951009190 active site 663951009191 substrate-binding site [chemical binding]; other site 663951009192 metal-binding site [ion binding] 663951009193 ATP binding site [chemical binding]; other site 663951009194 HMMPfam hit to PF01293, PEPCK_ATP, score 2.9e-303 663951009195 PS00017 ATP/GTP-binding site motif A (P-loop). 663951009196 Transposase IS200 like; Region: Y1_Tnp; pfam01797 663951009197 HMMPfam hit to PF01797, Transposase_17, score 8.4e-59 663951009198 Dipeptidyl aminopeptidases/acylaminoacyl-peptidases [Amino acid transport and metabolism]; Region: DAP2; COG1506 663951009199 Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326 663951009200 nucleoside triphosphatase YtkD; Region: nudix_YtkD; TIGR02705 663951009201 Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly...; Region: Nudix_Hydrolase_8; cd04665 663951009202 nudix motif; other site 663951009203 HMMPfam hit to PF00293, NUDIX, score 3.2e-10 663951009204 PS00893 mutT domain signature. 663951009205 Haemolytic domain; Region: Haemolytic; pfam01809 663951009206 HMMPfam hit to PF01809, DUF37, score 1.3e-40 663951009207 Enolase-superfamily, characterized by the presence of an enolate anion intermediate which is generated by abstraction of the alpha-proton of the carboxylate substrate by an active site residue and is stabilized by coordination to the essential Mg2+ ion; Region: enolase_like; cl17188 663951009208 o-succinylbenzoate synthase; Region: menC_lowGC/arch; TIGR01928 663951009209 metal binding site [ion binding]; metal-binding site 663951009210 substrate binding pocket [chemical binding]; other site 663951009211 O-succinylbenzoate-CoA ligase (also known as O-succinylbenzoate-CoA synthase, OSB-CoA synthetase, or MenE); Region: OSB_CoA_lg; cd05912 663951009212 O-succinylbenzoate-CoA ligase; Region: menE; TIGR01923 663951009213 acyl-activating enzyme (AAE) consensus motif; other site 663951009214 putative AMP binding site [chemical binding]; other site 663951009215 putative active site [active] 663951009216 putative CoA binding site [chemical binding]; other site 663951009217 HMMPfam hit to PF00501, AMP-binding, score 7.5e-83 663951009218 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 663951009219 Excalibur calcium-binding domain; Region: Excalibur; smart00894 663951009220 1 probable transmembrane helix predicted for SATW20_17880 by TMHMM2.0 at aa 20-42 663951009221 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 663951009222 HMMPfam hit to PF05901, Excalibur, score 1.2e-19 663951009223 Domain of unknown function (DUF4352); Region: DUF4352; pfam11611 663951009224 1 probable transmembrane helix predicted for SATW20_17890 by TMHMM2.0 at aa 39-61 663951009225 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 663951009226 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 663951009227 Protein of unknown function (DUF3969); Region: DUF3969; pfam13108 663951009228 Domain of unknown function (DUF955); Region: DUF955; pfam06114 663951009229 Genomic island niSa-beta 663951009230 HMMPfam hit to PF06114, DUF955, score 3.4e-24 663951009231 2 probable transmembrane helices predicted for SATW20_17950 by TMHMM2.0 at aa 7-24 and 34-56 663951009232 1 probable transmembrane helix predicted for SATW20_17960 by TMHMM2.0 at aa 67-89 663951009233 Probable gene remnant 663951009234 Probable gene remnant 663951009235 HMMPfam hit to PF01527, Transposase_8, score 2.4e-08 663951009236 Probable gene remnant 663951009237 Protein of unknown function (DUF1433); Region: DUF1433; pfam07252 663951009238 HMMPfam hit to PF07252, DUF1433, score 2.5e-59 663951009239 1 probable transmembrane helix predicted for SATW20_17990 by TMHMM2.0 at aa 5-22 663951009240 CDS is disrupted by the insertion of an IS element after codon 951 663951009241 CDS contains a frameshift after codon 267. Frameshift occurs at a poly A heptamer 663951009242 HMMPfam hit to PF00872, Transposase_mut, score 9.8e-228 663951009243 PS01007 Transposases, Mutator family, signature. 663951009244 PS00017 ATP/GTP-binding site motif A (P-loop). 663951009245 Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420 663951009246 Restriction endonuclease S subunits [Defense mechanisms]; Region: HsdS; COG0732 663951009247 Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420 663951009248 HMMPfam hit to PF01420, Methylase_S, score 5.4e-16 663951009249 HMMPfam hit to PF01420, Methylase_S, score 1.1e-23 663951009250 Type I restriction-modification system methyltransferase subunit [Defense mechanisms]; Region: HsdM; COG0286 663951009251 HsdM N-terminal domain; Region: HsdM_N; pfam12161 663951009252 S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440 663951009253 S-adenosylmethionine binding site [chemical binding]; other site 663951009254 HMMPfam hit to PF02384, N6_Mtase, score 1e-161 663951009255 PS00092 N-6 Adenine-specific DNA methylases signature. 663951009256 V8-like Glu-specific endopeptidase [Amino acid transport and metabolism]; Region: COG3591 663951009257 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain [Posttranslational modification, protein turnover, chaperones]; Region: DegQ; COG0265 663951009258 HMMPfam hit to PF00089, Trypsin, score 5.4e-18 663951009259 PS00672 Serine proteases, V8 family, histidine active site. 663951009260 2 probable transmembrane helices predicted for SATW20_18060 by TMHMM2.0 at aa 5-27 and 49-71 663951009261 V8-like Glu-specific endopeptidase [Amino acid transport and metabolism]; Region: COG3591 663951009262 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain [Posttranslational modification, protein turnover, chaperones]; Region: DegQ; COG0265 663951009263 HMMPfam hit to PF00089, Trypsin, score 3e-22 663951009264 PS00672 Serine proteases, V8 family, histidine active site. 663951009265 1 probable transmembrane helix predicted for SATW20_18070 by TMHMM2.0 at aa 5-27 663951009266 V8-like Glu-specific endopeptidase [Amino acid transport and metabolism]; Region: COG3591 663951009267 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain [Posttranslational modification, protein turnover, chaperones]; Region: DegQ; COG0265 663951009268 HMMPfam hit to PF00089, Trypsin, score 2.1e-14 663951009269 PS00672 Serine proteases, V8 family, histidine active site. 663951009270 2 probable transmembrane helices predicted for SATW20_18080 by TMHMM2.0 at aa 5-27 and 49-71 663951009271 V8-like Glu-specific endopeptidase [Amino acid transport and metabolism]; Region: COG3591 663951009272 HMMPfam hit to PF00089, Trypsin, score 3.5e-34 663951009273 PS00672 Serine proteases, V8 family, histidine active site. 663951009274 V8-like Glu-specific endopeptidase [Amino acid transport and metabolism]; Region: COG3591 663951009275 HMMPfam hit to PF00089, Trypsin, score 1.4e-36 663951009276 PS00672 Serine proteases, V8 family, histidine active site. 663951009277 1 probable transmembrane helix predicted for SATW20_18100 by TMHMM2.0 at aa 5-27 663951009278 V8-like Glu-specific endopeptidase [Amino acid transport and metabolism]; Region: COG3591 663951009279 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain [Posttranslational modification, protein turnover, chaperones]; Region: DegQ; COG0265 663951009280 HMMPfam hit to PF00089, Trypsin, score 6.8e-25 663951009281 PS00672 Serine proteases, V8 family, histidine active site. 663951009282 PS00097 Aspartate and ornithine carbamoyltransferases signature. 663951009283 6 probable transmembrane helices predicted for SATW20_18130 by TMHMM2.0 at aa 17-39, 49-71, 91-113,123-145, 152-174 and 197-219 663951009284 lantibiotic protection ABC transporter permease subunit, MutE/EpiE family; Region: lanti_perm_MutE; TIGR03732 663951009285 ABC-2 family transporter protein; Region: ABC2_membrane_4; pfam12730 663951009286 7 probable transmembrane helices predicted for SATW20_18140 by TMHMM2.0 at aa 13-35, 50-72, 104-126,136-158, 163-185, 195-214 and 227-244 663951009287 gallidermin-class lantibiotic protection ABC transporter, ATP-binding subunit; Region: galliderm_ABC; TIGR03740 663951009288 ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201 663951009289 Walker A/P-loop; other site 663951009290 ATP binding site [chemical binding]; other site 663951009291 Q-loop/lid; other site 663951009292 ABC transporter signature motif; other site 663951009293 Walker B; other site 663951009294 D-loop; other site 663951009295 H-loop/switch region; other site 663951009296 HMMPfam hit to PF00005, ABC_tran, score 1.3e-49 663951009297 PS00211 ABC transporters family signature. 663951009298 PS00017 ATP/GTP-binding site motif A (P-loop). 663951009299 Peptidase S8 family domain in Lantiobiotic (lanthionine-containing antibiotics) specific proteases; Region: Peptidases_S8_Lantibiotic_specific_protease; cd07482 663951009300 active site 663951009301 catalytic triad [active] 663951009302 HMMPfam hit to PF00082, Peptidase_S8, score 1.8e-53 663951009303 PS00138 Serine proteases, subtilase family, serine active site. 663951009304 PS00136 Serine proteases, subtilase family, aspartic acid active site. 663951009305 Phosphopantothenoylcysteine synthetase/decarboxylase [Coenzyme metabolism]; Region: Dfp; COG0452 663951009306 Flavoprotein; Region: Flavoprotein; pfam02441 663951009307 HMMPfam hit to PF02441, Flavoprotein, score 9.3e-29 663951009308 Lanthionine synthetase C-like protein; Region: LANC_like; pfam05147 663951009309 LanC is the cyclase enzyme of the lanthionine synthetase. Lanthinoine is a lantibiotic, a unique class of peptide antibiotics. They are ribosomally synthesized as precursor peptides and then post-translationally modified to contain thioether cross-links...; Region: LanC; cd04793 663951009310 active site 663951009311 zinc binding site [ion binding]; other site 663951009312 HMMPfam hit to PF05147, LANC_like, score 1.9e-112 663951009313 CDS contains a large internal deletion, 418 amino acids, in comparison to orthologues 663951009314 HMMPfam hit to PF04738, Lant_dehyd_C, score 1e-71 663951009315 HMMPfam hit to PF04737, Lant_dehyd_N, score 9.8e-58 663951009316 lantibiotic, gallidermin/nisin family; Region: lantibio_gallid; TIGR03731 663951009317 HMMPfam hit to PF02052, Gallidermin, score 1.2e-17 663951009318 lantibiotic, gallidermin/nisin family; Region: lantibio_gallid; TIGR03731 663951009319 beta-channel forming cytolysin; Region: hlyII; TIGR01002 663951009320 HMMPfam hit to PF07968, Leukocidin, score 4.2e-135 663951009321 Leukocidin/Hemolysin toxin family; Region: Leukocidin; pfam07968 663951009322 HMMPfam hit to PF07968, Leukocidin, score 4.3e-129 663951009323 CDS contains a frameshift after codon 211. Frameshift occurs at a poly A heptamer 663951009324 HMMPfam hit to PF08861, DUF1828, score 2.3e-42 663951009325 HMMPfam hit to PF08862, DUF1829, score 2.5e-41 663951009326 Predicted esterase of the alpha/beta hydrolase fold [General function prediction only]; Region: COG3545 663951009327 Alpha/beta hydrolase family; Region: Abhydrolase_5; pfam12695 663951009328 HMMPfam hit to PF06821, DUF1234, score 1.1e-05 663951009329 protoporphyrinogen oxidase; Reviewed; Region: PRK11883 663951009330 NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450 663951009331 HMMPfam hit to PF01593, Amino_oxidase, score 6.2e-27 663951009332 ferrochelatase; Provisional; Region: PRK12435 663951009333 Ferrochelatase, N-terminal domain: Ferrochelatase (protoheme ferrolyase or HemH) is the terminal enzyme of the heme biosynthetic pathway. It catalyzes the insertion of ferrous iron into the protoporphyrin IX ring yielding protoheme. This enzyme is...; Region: Ferrochelatase_N; cd03411 663951009334 C-terminal domain interface [polypeptide binding]; other site 663951009335 active site 663951009336 Ferrochelatase, C-terminal domain: Ferrochelatase (protoheme ferrolyase or HemH) is the terminal enzyme of the heme biosynthetic pathway. It catalyzes the insertion of ferrous iron into the protoporphyrin IX ring yielding protoheme. This enzyme is...; Region: Ferrochelatase_C; cd00419 663951009337 active site 663951009338 N-terminal domain interface [polypeptide binding]; other site 663951009339 HMMPfam hit to PF00762, Ferrochelatase, score 6e-85 663951009340 PS00435 Peroxidases proximal heme-ligand signature. 663951009341 Uroporphyrinogen decarboxylase (URO-D) is a dimeric cytosolic enzyme that decarboxylates the four acetate side chains of uroporphyrinogen III (uro-III) to create coproporphyrinogen III, without requiring any prosthetic groups or cofactors. This reaction...; Region: URO-D; cd00717 663951009342 substrate binding site [chemical binding]; other site 663951009343 active site 663951009344 HMMPfam hit to PF01208, URO-D, score 1.8e-160 663951009345 PS00907 Uroporphyrinogen decarboxylase signature 2. 663951009346 PS00906 Uroporphyrinogen decarboxylase signature 1. 663951009347 Antibiotic biosynthesis monooxygenase; Region: ABM; cl10022 663951009348 Predicted ABC-type exoprotein transport system, permease component [Intracellular trafficking and secretion]; Region: EcsB; COG4473 663951009349 HMMPfam hit to PF05975, EcsB, score 3.2e-218 663951009350 10 probable transmembrane helices predicted for SATW20_18300 by TMHMM2.0 at aa 26-48, 58-80, 101-123,133-151, 164-183, 187-204, 285-302, 306-328, 353-371 and 376-395 663951009351 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 663951009352 ABC-type Na+ transport system, ATPase component [Energy production and conversion / Inorganic ion transport and metabolism]; Region: NatA; COG4555 663951009353 ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230 663951009354 Walker A/P-loop; other site 663951009355 ATP binding site [chemical binding]; other site 663951009356 Q-loop/lid; other site 663951009357 ABC transporter signature motif; other site 663951009358 Walker B; other site 663951009359 D-loop; other site 663951009360 H-loop/switch region; other site 663951009361 HMMPfam hit to PF00005, ABC_tran, score 4.3e-49 663951009362 PS00211 ABC transporters family signature. 663951009363 PS00017 ATP/GTP-binding site motif A (P-loop). 663951009364 HINT (histidine triad nucleotide-binding protein) subgroup: Members of this CD belong to the superfamily of histidine triad hydrolases that act on alpha-phosphate of ribonucleotides. This subgroup includes members from all three forms of cellular life; Region: HINT_subgroup; cd01277 663951009365 HIT family signature motif; other site 663951009366 catalytic residue [active] 663951009367 HMMPfam hit to PF01230, HIT, score 4.2e-37 663951009368 PS00892 HIT family signature. 663951009369 Gas vesicle protein [General function prediction only]; Region: GvpP; COG4980 663951009370 1 probable transmembrane helix predicted for SATW20_18330 by TMHMM2.0 at aa 5-22 663951009371 Protein of unknown function (DUF3267); Region: DUF3267; pfam11667 663951009372 4 probable transmembrane helices predicted for SATW20_18340 by TMHMM2.0 at aa 19-41, 51-73, 105-127 and 137-159 663951009373 peptidylprolyl isomerase; Reviewed; Region: prsA; PRK03095 663951009374 SurA N-terminal domain; Region: SurA_N_3; cl07813 663951009375 PPIC-type PPIASE domain; Region: Rotamase; pfam00639 663951009376 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 663951009377 HMMPfam hit to PF00639, Rotamase, score 8.7e-27 663951009378 3'-5' exoribonuclease YhaM; Provisional; Region: PRK13480 663951009379 YhaM_OBF_like: A subfamily of OB folds similar to that found in Bacillus subtilis YhaM and Staphylococcus aureus cmp-binding factor-1 (SaCBF1). Both these proteins are 3'-to-5'exoribonucleases. YhaM requires Mn2+ or Co2+ for activity and is...; Region: YhaM_OBF_like; cd04492 663951009380 generic binding surface II; other site 663951009381 generic binding surface I; other site 663951009382 Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077 663951009383 Zn2+ binding site [ion binding]; other site 663951009384 Mg2+ binding site [ion binding]; other site 663951009385 HMMPfam hit to PF01966, HD, score 1.6e-13 663951009386 HMMPfam hit to PF01336, tRNA_anti, score 3.1e-07 663951009387 Uncharacterized conserved protein [Function unknown]; Region: COG4717 663951009388 P-loop containing region of AAA domain; Region: AAA_29; cl17516 663951009389 Plant specific eukaryotic initiation factor 4B; Region: eIF-4B; pfam06273 663951009390 2 probable transmembrane helices predicted for SATW20_18370 by TMHMM2.0 at aa 465-482 and 487-506 663951009391 PS00017 ATP/GTP-binding site motif A (P-loop). 663951009392 DNA repair exonuclease [DNA replication, recombination, and repair]; Region: SbcD; COG0420 663951009393 Mre11 nuclease, N-terminal metallophosphatase domain; Region: MPP_Mre11_N; cd00840 663951009394 active site 663951009395 metal binding site [ion binding]; metal-binding site 663951009396 DNA binding site [nucleotide binding] 663951009397 HMMPfam hit to PF00149, Metallophos, score 3.9e-20 663951009398 hypothetical protein; Provisional; Region: PRK13676 663951009399 HMMPfam hit to PF06133, DUF964, score 1.8e-60 663951009400 Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4399 663951009401 HMMPfam hit to PF04286, DUF445, score 4.8e-159 663951009402 2 probable transmembrane helices predicted for SATW20_18400 by TMHMM2.0 at aa 4-26 and 351-373 663951009403 Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396 663951009404 Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093 663951009405 non-specific DNA binding site [nucleotide binding]; other site 663951009406 salt bridge; other site 663951009407 sequence-specific DNA binding site [nucleotide binding]; other site 663951009408 Predicted helix-turn-helix motif with score 983.000,SD 2.53 at aa 23-44, sequence YTQDTMAQTIGLSKKTLVQIEK 663951009409 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197 663951009410 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 663951009411 active site 663951009412 phosphorylation site [posttranslational modification] 663951009413 intermolecular recognition site; other site 663951009414 dimerization interface [polypeptide binding]; other site 663951009415 C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170 663951009416 DNA binding residues [nucleotide binding] 663951009417 dimerization interface [polypeptide binding]; other site 663951009418 HMMPfam hit to PF00196, GerE, score 4.7e-27 663951009419 PS00622 Bacterial regulatory proteins, luxR family signature. 663951009420 Predicted helix-turn-helix motif with score 1251.000, SD 3.45 at aa 162-183, sequence KTNKEIAETLFVSEKTIKTHVS 663951009421 HMMPfam hit to PF00072, Response_reg, score 9.5e-37 663951009422 FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203 663951009423 GAF domain; Region: GAF_3; pfam13492 663951009424 Signal transduction histidine kinase [Signal transduction mechanisms]; Region: COG4585 663951009425 Histidine kinase; Region: HisKA_3; pfam07730 663951009426 Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075 663951009427 ATP binding site [chemical binding]; other site 663951009428 Mg2+ binding site [ion binding]; other site 663951009429 G-X-G motif; other site 663951009430 HMMPfam hit to PF02518, HATPase_c, score 2.1e-14 663951009431 HMMPfam hit to PF07730, HisKA_3, score 1e-20 663951009432 HMMPfam hit to PF01590, GAF, score 0.00098 663951009433 Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564 663951009434 Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869 663951009435 active site 663951009436 HMMPfam hit to PF00849, PseudoU_synth_2, score 3.7e-35 663951009437 fumarate hydratase; Reviewed; Region: fumC; PRK00485 663951009438 Class II fumarases; Region: Fumarase_classII; cd01362 663951009439 active site 663951009440 tetramer interface [polypeptide binding]; other site 663951009441 HMMPfam hit to PF00206, Lyase_1, score 2e-164 663951009442 PS00163 Fumarate lyases signature. 663951009443 3 probable transmembrane helices predicted for SATW20_18460 by TMHMM2.0 at aa 10-32, 66-85 and 100-122 663951009444 SugarP_isomerase: Sugar Phosphate Isomerase family; includes type A ribose 5-phosphate isomerase (RPI_A), glucosamine-6-phosphate (GlcN6P) deaminase, and 6-phosphogluconolactonase (6PGL). RPI catalyzes the reversible conversion of ribose-5-phosphate to...; Region: SugarP_isomerase; cl00339 663951009445 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase [Carbohydrate transport and metabolism]; Region: NagB; COG0363 663951009446 active site 663951009447 Predicted rRNA methylase (SpoU class) [Translation, ribosomal structure and biogenesis]; Region: CspR; COG0219 663951009448 HMMPfam hit to PF00588, SpoU_methylase, score 4.3e-43 663951009449 epoxyqueuosine reductase; Region: TIGR00276 663951009450 Domain of unknown function (DUF1730); Region: DUF1730; pfam08331 663951009451 HEAT repeats; Region: HEAT_2; pfam13646 663951009452 HMMPfam hit to PF00037, Fer4, score 0.0019 663951009453 PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature. 663951009454 HMMPfam hit to PF08331, DUF1730, score 4.4e-36 663951009455 ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126 663951009456 ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262 663951009457 Walker A/P-loop; other site 663951009458 ATP binding site [chemical binding]; other site 663951009459 Q-loop/lid; other site 663951009460 ABC transporter signature motif; other site 663951009461 Walker B; other site 663951009462 D-loop; other site 663951009463 H-loop/switch region; other site 663951009464 HMMPfam hit to PF00005, ABC_tran, score 6.6e-71 663951009465 PS00211 ABC transporters family signature. 663951009466 PS00017 ATP/GTP-binding site motif A (P-loop). 663951009467 Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134 663951009468 Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497 663951009469 substrate binding pocket [chemical binding]; other site 663951009470 membrane-bound complex binding site; other site 663951009471 hinge residues; other site 663951009472 ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215 663951009473 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 663951009474 dimer interface [polypeptide binding]; other site 663951009475 conserved gate region; other site 663951009476 putative PBP binding loops; other site 663951009477 ABC-ATPase subunit interface; other site 663951009478 HMMPfam hit to PF00528, BPD_transp_1, score 3.7e-35 663951009479 3 probable transmembrane helices predicted for SATW20_18520 by TMHMM2.0 at aa 287-309, 334-356 and 448-470 663951009480 PS00402 Binding-protein-dependent transport systems inner membrane comp. sign. 663951009481 HMMPfam hit to PF00497, SBP_bac_3, score 3.9e-61 663951009482 Predicted membrane protein, putative toxin regulator [General function prediction only]; Region: PfoR; COG3641 663951009483 Phosphotransferase system, EIIC; Region: PTS_EIIC_2; pfam13303 663951009484 10 probable transmembrane helices predicted for SATW20_18530 by TMHMM2.0 at aa 12-34, 49-71, 78-97,107-129, 136-158, 178-200, 207-229, 233-255, 258-280 and 309-331 663951009485 HMMPfam hit to PF02378, PTS_EIIC, score 2.2e-22 663951009486 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 663951009487 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 663951009488 Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3464 663951009489 Transposase; Region: DDE_Tnp_ISL3; pfam01610 663951009490 Predicted helix-turn-helix motif with score 1283.000, SD 3.56 at aa 124-145, sequence KTEIDTAEDNCISPSTVSRIRT 663951009491 HMMPfam hit to PF01610, Transposase_12, score 1.5e-49 663951009492 Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators; Region: Fur_like; cd07153 663951009493 metal binding site 2 [ion binding]; metal-binding site 663951009494 putative DNA binding helix; other site 663951009495 metal binding site 1 [ion binding]; metal-binding site 663951009496 dimer interface [polypeptide binding]; other site 663951009497 structural Zn2+ binding site [ion binding]; other site 663951009498 HMMPfam hit to PF01475, FUR, score 2.5e-54 663951009499 Phosphoglycerate Dehydrogenase, 2-hydroxyacid dehydrogenase family; Region: PGDH_1; cd12155 663951009500 Phosphoglycerate dehydrogenase and related dehydrogenases [Amino acid transport and metabolism]; Region: SerA; COG0111 663951009501 putative ligand binding site [chemical binding]; other site 663951009502 NAD binding site [chemical binding]; other site 663951009503 catalytic site [active] 663951009504 HMMPfam hit to PF00389, 2-Hacid_dh, score 2.8e-37 663951009505 HMMPfam hit to PF02826, 2-Hacid_dh_C, score 1.8e-63 663951009506 Peroxiredoxin [Posttranslational modification, protein turnover, chaperones]; Region: AhpC; COG0450 663951009507 Peroxiredoxin (PRX) family, Bacterioferritin comigratory protein (BCP) subfamily; composed of thioredoxin-dependent thiol peroxidases, widely expressed in pathogenic bacteria, that protect cells against toxicity from reactive oxygen species by reducing...; Region: PRX_BCP; cd03017 663951009508 catalytic triad [active] 663951009509 HMMPfam hit to PF00578, AhpC-TSA, score 1.3e-40 663951009510 glutamate-1-semialdehyde aminotransferase; Provisional; Region: PRK12389 663951009511 Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610 663951009512 inhibitor-cofactor binding pocket; inhibition site 663951009513 pyridoxal 5'-phosphate binding site [chemical binding]; other site 663951009514 catalytic residue [active] 663951009515 HMMPfam hit to PF00202, Aminotran_3, score 3.5e-74 663951009516 Predicted membrane protein [Function unknown]; Region: COG4129 663951009517 Bacterial protein of unknown function (DUF939); Region: DUF939; pfam06081 663951009518 HMMPfam hit to PF06081, DUF939, score 1.2e-26 663951009519 4 probable transmembrane helices predicted for SATW20_18590 by TMHMM2.0 at aa 7-24, 57-79, 86-108 and 123-145 663951009520 ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132 663951009521 ABC transporter transmembrane region; Region: ABC_membrane; pfam00664 663951009522 ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; Region: ABCC_MsbA; cd03251 663951009523 Walker A/P-loop; other site 663951009524 ATP binding site [chemical binding]; other site 663951009525 Q-loop/lid; other site 663951009526 ABC transporter signature motif; other site 663951009527 Walker B; other site 663951009528 D-loop; other site 663951009529 H-loop/switch region; other site 663951009530 HMMPfam hit to PF00005, ABC_tran, score 6.1e-63 663951009531 PS00211 ABC transporters family signature. 663951009532 PS00017 ATP/GTP-binding site motif A (P-loop). 663951009533 HMMPfam hit to PF00664, ABC_membrane, score 1.9e-46 663951009534 5 probable transmembrane helices predicted for SATW20_18600 by TMHMM2.0 at aa 19-41, 56-73, 136-158,163-185 and 260-282 663951009535 hypothetical protein; Provisional; Region: PRK13662 663951009536 HMMPfam hit to PF04167, DUF402, score 4.3e-46 663951009537 A/G-specific DNA glycosylase [DNA replication, recombination, and repair]; Region: MutY; COG1194 663951009538 endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056 663951009539 minor groove reading motif; other site 663951009540 helix-hairpin-helix signature motif; other site 663951009541 substrate binding pocket [chemical binding]; other site 663951009542 active site 663951009543 Iron-sulfur binding domain of endonuclease III; Region: EndIII_4Fe-2S; pfam10576 663951009544 DNA glycosylase (MutY in bacteria and hMYH in humans) is responsible for repairing misread A*oxoG residues to C*G by removing the inappropriately paired adenine base from the DNA backbone. It belongs to the Nudix hydrolase superfamily and is important...; Region: DNA_Glycosylase_C; cd03431 663951009545 DNA binding and oxoG recognition site [nucleotide binding] 663951009546 HMMPfam hit to PF00730, HhH-GPD, score 5.7e-14 663951009547 HMMPfam hit to PF00633, HHH, score 5e-07 663951009548 Predicted membrane-bound metal-dependent hydrolases [General function prediction only]; Region: COG1988 663951009549 HMMPfam hit to PF04307, DUF457, score 1.3e-35 663951009550 4 probable transmembrane helices predicted for SATW20_18630 by TMHMM2.0 at aa 65-87, 92-114, 127-149 and 154-171 663951009551 7 probable transmembrane helices predicted for SATW20_18640 by TMHMM2.0 at aa 29-51, 61-83, 95-117,132-154, 166-185, 195-217 and 224-246 663951009552 ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: TagH; COG1134 663951009553 ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201 663951009554 Walker A/P-loop; other site 663951009555 ATP binding site [chemical binding]; other site 663951009556 Q-loop/lid; other site 663951009557 ABC transporter signature motif; other site 663951009558 Walker B; other site 663951009559 H-loop/switch region; other site 663951009560 Predicted helix-turn-helix motif with score 1121.000, SD 3.00 at aa 396-417, sequence HSFKKLAPYMKSNYSNYYAYFN 663951009561 1 probable transmembrane helix predicted for SATW20_18650 by TMHMM2.0 at aa 285-307 663951009562 Protein of unknown function (DUF1811); Region: DUF1811; pfam08838 663951009563 HMMPfam hit to PF08838, DUF1811, score 7.7e-58 663951009564 recombination regulator RecX; Provisional; Region: recX; PRK14135 663951009565 HMMPfam hit to PF02631, RecX, score 0.0013 663951009566 glycosyltransferase; Provisional; Region: PRK13481 663951009567 Transglycosylase; Region: Transgly; pfam00912 663951009568 HMMPfam hit to PF00912, Transgly, score 1.7e-71 663951009569 1 probable transmembrane helix predicted for SATW20_18680 by TMHMM2.0 at aa 42-64 663951009570 intracellular protease, PfpI family; Region: PfpI; TIGR01382 663951009571 A type 1 glutamine amidotransferase (GATase1)-like domain found in PfpI from Pyrococcus furiosus; Region: GATase1_PfpI_like; cd03134 663951009572 proposed catalytic triad [active] 663951009573 conserved cys residue [active] 663951009574 HMMPfam hit to PF01965, DJ-1_PfpI, score 4.8e-52 663951009575 Predicted Fe-S oxidoreductases [General function prediction only]; Region: COG0535 663951009576 Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335 663951009577 FeS/SAM binding site; other site 663951009578 YfkB-like domain; Region: YfkB; pfam08756 663951009579 HMMPfam hit to PF04055, Radical_SAM, score 2.1e-12 663951009580 HMMPfam hit to PF08756, YfkB, score 2.8e-109 663951009581 Brown fat-inducible thioesterase (BFIT). Brain acyl-CoA hydrolase (BACH). These enzymes deacylate long-chain fatty acids by hydrolyzing acyl-CoA thioesters to free fatty acids and CoA-SH. Eukaryotic members of this family are expressed in brain, testis; Region: BFIT_BACH; cd03442 663951009582 HMMPfam hit to PF03061, 4HBT, score 1.3e-18 663951009583 Thermophilic metalloprotease (M29); Region: Peptidase_M29; pfam02073 663951009584 Leucyl aminopeptidase (aminopeptidase T) [Amino acid transport and metabolism]; Region: AmpS; COG2309 663951009585 HMMPfam hit to PF02073, Peptidase_M29, score 1.4e-160 663951009586 Protein of unknown function (DUF1128); Region: DUF1128; cl11553 663951009587 HMMPfam hit to PF06569, DUF1128, score 1.9e-37 663951009588 Protein-tyrosine-phosphatase [Signal transduction mechanisms]; Region: Wzb; COG0394 663951009589 Low molecular weight phosphatase family; Region: LMWPc; cd00115 663951009590 active site 663951009591 HMMPfam hit to PF01451, LMWPc, score 2.6e-39 663951009592 1 probable transmembrane helix predicted for SATW20_18760 by TMHMM2.0 at aa 5-22 663951009593 Virulence factor BrkB; Region: Virul_fac_BrkB; pfam03631 663951009594 HMMPfam hit to PF03631, Ribonuclease_BN, score 2.2e-106 663951009595 6 probable transmembrane helices predicted for SATW20_18770 by TMHMM2.0 at aa 95-117, 157-179, 192-214,234-256, 269-291 and 301-323 663951009596 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197 663951009597 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 663951009598 active site 663951009599 phosphorylation site [posttranslational modification] 663951009600 intermolecular recognition site; other site 663951009601 dimerization interface [polypeptide binding]; other site 663951009602 C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170 663951009603 DNA binding residues [nucleotide binding] 663951009604 dimerization interface [polypeptide binding]; other site 663951009605 HMMPfam hit to PF00196, GerE, score 1.4e-22 663951009606 HMMPfam hit to PF00072, Response_reg, score 2.3e-36 663951009607 Signal transduction histidine kinase [Signal transduction mechanisms]; Region: COG4585 663951009608 Histidine kinase; Region: HisKA_3; pfam07730 663951009609 Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075 663951009610 ATP binding site [chemical binding]; other site 663951009611 Mg2+ binding site [ion binding]; other site 663951009612 G-X-G motif; other site 663951009613 HMMPfam hit to PF02518, HATPase_c, score 1.8e-19 663951009614 HMMPfam hit to PF07730, HisKA_3, score 3e-21 663951009615 2 probable transmembrane helices predicted for SATW20_18790 by TMHMM2.0 at aa 13-35 and 45-67 663951009616 Predicted membrane protein [Function unknown]; Region: COG4758 663951009617 Cell wall-active antibiotics response protein (DUF2154); Region: DUF2154; pfam09922 663951009618 4 probable transmembrane helices predicted for SATW20_18800 by TMHMM2.0 at aa 5-27, 31-49, 56-73 and 77-94 663951009619 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 663951009620 Methionine Aminopeptidase 1. E.C. 3.4.11.18. Also known as methionyl aminopeptidase and Peptidase M. Catalyzes release of N-terminal amino acids, preferentially methionine, from peptides and arylamides; Region: MetAP1; cd01086 663951009621 active site 663951009622 HMMPfam hit to PF00557, Peptidase_M24, score 1.4e-52 663951009623 Predicted membrane protein [Function unknown]; Region: COG4129 663951009624 Bacterial protein of unknown function (DUF939); Region: DUF939; pfam06081 663951009625 HMMPfam hit to PF06081, DUF939, score 4.7e-23 663951009626 4 probable transmembrane helices predicted for SATW20_18830 by TMHMM2.0 at aa 18-40, 61-79, 89-111 and 123-145 663951009627 Type 1 glutamine amidotransferase (GATase1) domain found in Cobyric Acid Synthase (CobQ); Region: GATase1_CobQ; cd01750 663951009628 catalytic triad [active] 663951009629 HMMPfam hit to PF07685, GATase_3, score 3.8e-42 663951009630 UDP-N-acetylmuramyl tripeptide synthase [Cell envelope biogenesis, outer membrane]; Region: MurE; COG0769 663951009631 Mur ligase middle domain; Region: Mur_ligase_M; pfam08245 663951009632 Domain of unknown function (DUF1727); Region: DUF1727; pfam08353 663951009633 HMMPfam hit to PF08353, DUF1727, score 1.2e-53 663951009634 HMMPfam hit to PF08245, Mur_ligase_M, score 6.2e-07 663951009635 nonheme-containing ferritins; Region: Nonheme_Ferritin; cd01055 663951009636 Ferritin-like domain; Region: Ferritin; pfam00210 663951009637 ferroxidase diiron center [ion binding]; other site 663951009638 HMMPfam hit to PF00210, Ferritin, score 4.8e-48 663951009639 an uncharacterized bacterial subgroup of the DEDDh 3'-5' exonuclease domain family with similarity to the epsilon subunit of DNA polymerase III; Region: DNA_pol_III_epsilon_like; cd06130 663951009640 active site 663951009641 catalytic site [active] 663951009642 substrate binding site [chemical binding]; other site 663951009643 HMMPfam hit to PF00929, Exonuc_X-T, score 1.7e-24 663951009644 DNA Polymerase IV/Kappa; Region: PolY_Pol_IV_kappa; cd03586 663951009645 active site 663951009646 DNA polymerase IV; Validated; Region: PRK02406 663951009647 DNA binding site [nucleotide binding] 663951009648 HMMPfam hit to PF00817, IMS, score 1.2e-112 663951009649 Protein of unknown function (DUF3267); Region: DUF3267; pfam11667 663951009650 4 probable transmembrane helices predicted for SATW20_18900 by TMHMM2.0 at aa 15-37, 50-72, 104-126 and 131-153 663951009651 TRAM domain; Region: TRAM; cl01282 663951009652 SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase [Translation, ribosomal structure and biogenesis]; Region: TrmA; COG2265 663951009653 S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440 663951009654 S-adenosylmethionine binding site [chemical binding]; other site 663951009655 PS01231 RNA methyltransferase trmA family signature 2. 663951009656 PS01230 RNA methyltransferase trmA family signature 1. 663951009657 HMMPfam hit to PF02475, Met_10, score 0.0014 663951009658 putative lipid kinase; Reviewed; Region: PRK13337 663951009659 Diacylglycerol kinase catalytic domain; Region: DAGK_cat; pfam00781 663951009660 Diacylglycerol kinase catalytic domain; Region: DAGK_cat; cl17465 663951009661 HMMPfam hit to PF00781, DAGK_cat, score 4e-50 663951009662 aspartyl/glutamyl-tRNA amidotransferase subunit B; Validated; Region: gatB; PRK05477 663951009663 GatB/GatE catalytic domain; Region: GatB_N; pfam02934 663951009664 GatB domain; Region: GatB_Yqey; pfam02637 663951009665 HMMPfam hit to PF02637, GatB_Yqey, score 1.5e-70 663951009666 HMMPfam hit to PF01162, GatB, score 3.2e-39 663951009667 HMMPfam hit to PF02934, GatB_N, score 9.2e-157 663951009668 PS01234 PET112 family signature. 663951009669 Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases [Translation, ribosomal structure and biogenesis]; Region: GatA; COG0154 663951009670 aspartyl/glutamyl-tRNA amidotransferase subunit A; Reviewed; Region: gatA; PRK00012 663951009671 HMMPfam hit to PF01425, Amidase, score 1.8e-203 663951009672 PS00571 Amidases signature. 663951009673 aspartyl/glutamyl-tRNA amidotransferase subunit C; Reviewed; Region: gatC; PRK00034 663951009674 HMMPfam hit to PF02686, Glu-tRNAGln, score 1.5e-20 663951009675 Predicted symporter [General function prediction only]; Region: DhlC; COG4147 663951009676 Na(+)/proline cotransporter PutP and related proteins; solute binding domain; Region: SLC5sbd_PutP; cd11475 663951009677 Na binding site [ion binding]; other site 663951009678 13 probable transmembrane helices predicted for SATW20_18970 by TMHMM2.0 at aa 15-37, 49-71, 86-105,137-159, 174-196, 203-225, 245-267, 288-310, 320-342,382-400, 410-432, 439-458 and 468-487 663951009679 HMMPfam hit to PF00474, SSF, score 7.4e-118 663951009680 PS00225 Crystallins beta and gamma 'Greek key' motif signature. 663951009681 Protein involved in sex pheromone biosynthesis [General function prediction only]; Region: CamS; COG4851 663951009682 N-terminal repeat domain of CamS sex pheromone cAM373 precursor; Region: CamS_repeat_1; cd13441 663951009683 putative dimer interface [polypeptide binding]; other site 663951009684 C-terminal repeat domain of CamS sex pheromone cAM373 precursor; Region: CamS_repeat_2; cd13440 663951009685 putative dimer interface [polypeptide binding]; other site 663951009686 HMMPfam hit to PF07537, CamS, score 4.6e-191 663951009687 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 663951009688 NAD-dependent DNA ligase LigA; Validated; Region: ligA; PRK07956 663951009689 NAD+ dependent DNA ligase adenylation domain. DNA ligases catalyze the crucial step of joining the breaks in duplex DNA during DNA replication, repair and recombination, utilizing either ATP or NAD(+) as a cofactor, but using the same basic reaction...; Region: LIGANc; cd00114 663951009690 nucleotide binding pocket [chemical binding]; other site 663951009691 K-X-D-G motif; other site 663951009692 catalytic site [active] 663951009693 NAD-dependent DNA ligase OB-fold domain; Region: DNA_ligase_OB; pfam03120 663951009694 NAD-dependent DNA ligase C4 zinc finger domain; Region: DNA_ligase_ZBD; pfam03119 663951009695 Breast Cancer Suppressor Protein (BRCA1), carboxy-terminal domain. The BRCT domain is found within many DNA damage repair and cell cycle checkpoint proteins. The unique diversity of this domain superfamily allows BRCT modules to interact forming homo...; Region: BRCT; cd00027 663951009696 Dimer interface [polypeptide binding]; other site 663951009697 HMMPfam hit to PF00533, BRCT, score 3.3e-17 663951009698 HMMPfam hit to PF03119, DNA_ligase_ZBD, score 1.4e-14 663951009699 HMMPfam hit to PF03120, DNA_ligase_OB, score 4.5e-48 663951009700 PS01056 NAD-dependent DNA ligase signature 2. 663951009701 HMMPfam hit to PF01653, DNA_ligase_aden, score 3.5e-188 663951009702 PS01055 NAD-dependent DNA ligase signature 1. 663951009703 ATP-dependent DNA helicase PcrA; Region: pcrA; TIGR01073 663951009704 Part of AAA domain; Region: AAA_19; pfam13245 663951009705 Family description; Region: UvrD_C_2; pfam13538 663951009706 HMMPfam hit to PF00580, UvrD-helicase, score 4.3e-250 663951009707 PS00017 ATP/GTP-binding site motif A (P-loop). 663951009708 PcrB family; Region: PcrB; pfam01884 663951009709 PcrB_like proteins. One member of this family, a protein from Archaeoglobus fulgidus, has been characterized as a (S)-3-O-geranylgeranylglyceryl phosphate synthase (AfGGGPS). AfGGGPS catalyzes the formation of an ether linkage between...; Region: PcrB_like; cd02812 663951009710 substrate binding site [chemical binding]; other site 663951009711 putative active site [active] 663951009712 dimer interface [polypeptide binding]; other site 663951009713 HMMPfam hit to PF01884, PcrB, score 4e-147 663951009714 Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4496 663951009715 HMMPfam hit to PF01371, Trp_repressor, score 1.1e-45 663951009716 Predicted helix-turn-helix motif with score 1037.000, SD 2.72 at aa 57-78, sequence YTYATIEQESGASTATISRVKR 663951009717 Adenylosuccinate lyase [Nucleotide transport and metabolism]; Region: PurB; COG0015 663951009718 Adenylsuccinate lyase (ASL)_subgroup 1; Region: Adenylsuccinate_lyase_1; cd01360 663951009719 tetramer interface [polypeptide binding]; other site 663951009720 active site 663951009721 Adenylosuccinate lyase C-terminus; Region: ADSL_C; smart00998 663951009722 HMMPfam hit to PF00206, Lyase_1, score 1.5e-96 663951009723 PS00163 Fumarate lyases signature. 663951009724 Staphopain peptidase C47; Region: Peptidase_C47; pfam05543 663951009725 HMMPfam hit to PF05543, Peptidase_C47, score 3.2e-138 663951009726 PS00639 Eukaryotic thiol (cysteine) proteases histidine active site. 663951009727 NETI protein; Region: NETI; pfam14044 663951009728 Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4843 663951009729 Uncharacterized protein conserved in bacteria (DUF2179); Region: DUF2179; pfam10035 663951009730 3 probable transmembrane helices predicted for SATW20_19060 by TMHMM2.0 at aa 10-32, 39-61 and 66-83 663951009731 NAD synthase [Coenzyme metabolism]; Region: NadE; COG0171 663951009732 NAD+ synthase is a homodimer, which catalyzes the final step in de novo nicotinamide adenine dinucleotide (NAD+) biosynthesis, an amide transfer from either ammonia or glutamine to nicotinic acid adenine dinucleotide (NaAD). The conversion of NaAD to NAD...; Region: NAD_synthase; cd00553 663951009733 homodimer interface [polypeptide binding]; other site 663951009734 NAD binding pocket [chemical binding]; other site 663951009735 ATP binding pocket [chemical binding]; other site 663951009736 Mg binding site [ion binding]; other site 663951009737 active-site loop [active] 663951009738 HMMPfam hit to PF02540, NAD_synthase, score 3.7e-98 663951009739 nicotinate phosphoribosyltransferase; Validated; Region: PRK09243 663951009740 Nicotinate phosphoribosyltransferase (NAPRTase), subgroup A. Nicotinate phosphoribosyltransferase catalyses the formation of NAMN and PPi from 5-phosphoribosy -1-pyrophosphate (PRPP) and nicotinic acid, this is the first, and also rate limiting, reaction...; Region: NAPRTase_A; cd01570 663951009741 active site 663951009742 HMMPfam hit to PF04095, NAPRTase, score 7.2e-13 663951009743 Nitric oxide synthase (NOS) prokaryotic oxygenase domain. NOS produces nitric oxide (NO) by catalyzing a five-electron heme-based oxidation of a guanidine nitrogen of L-arginine to L-citrulline via two successive monooxygenation reactions producing N...; Region: NOS_oxygenase_prok; cd00794 663951009744 active site 663951009745 dimer interface [polypeptide binding]; other site 663951009746 HMMPfam hit to PF02898, NO_synthase, score 2.5e-111 663951009747 Prephenate dehydratase [Amino acid transport and metabolism]; Region: PheA; COG0077 663951009748 Prephenate dehydratase; Region: PDT; pfam00800 663951009749 C-terminal ACT domain of the bifunctional chorismate mutase-prephenate dehydratase (CM-PDT) enzyme and the prephenate dehydratase (PDT) enzyme; Region: ACT_CM-PDT; cd04905 663951009750 putative L-Phe binding site [chemical binding]; other site 663951009751 HMMPfam hit to PF00800, PDT, score 4.5e-30 663951009752 HMMPfam hit to PF01842, ACT, score 2.3e-06 663951009753 Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Region: CitT; COG0471 663951009754 Permease SLC13 (solute carrier 13). The sodium/dicarboxylate cotransporter NaDC-1 has been shown to translocate Krebs cycle intermediates such as succinate, citrate, and alpha-ketoglutarate across plasma membranes rabbit, human, and rat kidney. It is...; Region: SLC13_permease; cd01115 663951009755 transmembrane helices; other site 663951009756 HMMPfam hit to PF00939, Na_sulph_symp, score 6.6e-59 663951009757 14 probable transmembrane helices predicted for SATW20_19110 by TMHMM2.0 at aa 28-50, 57-74, 78-97,110-127, 158-180, 205-227, 242-264, 299-318, 323-345,365-387, 397-419, 426-448, 452-474 and 487-509 663951009758 Pectate lyase superfamily protein; Region: Pectate_lyase_3; pfam12708 663951009759 PS00435 Peroxidases proximal heme-ligand signature. 663951009760 Isochorismatase family; Region: Isochorismatase; pfam00857 663951009761 Cysteine hydrolases; This family contains amidohydrolases, like CSHase (N-carbamoylsarcosine amidohydrolase), involved in creatine metabolism and nicotinamidase, converting nicotinamide to nicotinic acid and ammonia in the pyridine nucleotide cycle. It...; Region: cysteine_hydrolases; cd00431 663951009762 catalytic triad [active] 663951009763 conserved cis-peptide bond; other site 663951009764 HMMPfam hit to PF00857, Isochorismatase, score 2.6e-07 663951009765 putative manganese-dependent inorganic pyrophosphatase; Provisional; Region: PRK05427 663951009766 DHH family; Region: DHH; pfam01368 663951009767 DHHA2 domain; Region: DHHA2; pfam02833 663951009768 HMMPfam hit to PF01368, DHH, score 5.1e-17 663951009769 HMMPfam hit to PF02833, DHHA2, score 3.1e-40 663951009770 aldehyde dehydrogenase family protein; Provisional; Region: PTZ00381 663951009771 Bacillus subtilis aldehyde dehydrogenase ywdH-like; Region: ALDH_YwdH-P39616; cd07136 663951009772 NAD(P) binding site [chemical binding]; other site 663951009773 catalytic residues [active] 663951009774 HMMPfam hit to PF00171, Aldedh, score 3.5e-64 663951009775 PS00687 Aldehyde dehydrogenases glutamic acid active site. 663951009776 PS00070 Aldehyde dehydrogenases cysteine active site. 663951009777 3-carboxymuconate cyclase [Carbohydrate transport and metabolism]; Region: COG2706 663951009778 PS00294 Prenyl group binding site (CAAX box). 663951009779 YolD-like protein; Region: YolD; pfam08863 663951009780 HMMPfam hit to PF08863, YolD, score 4.2e-38 663951009781 1 probable transmembrane helix predicted for SATW20_19180 by TMHMM2.0 at aa 12-34 663951009782 Choloylglycine hydrolase (CGH)_like. This family of choloylglycine hydrolase-like proteins includes conjugated bile acid hydrolase (CBAH), penicillin V acylase (PVA), acid ceramidase (AC), and N-acylethanolamine-hydrolyzing acid amidase (NAAA) which...; Region: Ntn_CGH_like; cd01935 663951009783 active site 663951009784 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase; Region: AAT; pfam03417 663951009785 HMMPfam hit to PF03417, AAT, score 3e-95 663951009786 Domain of unknown function (DUF4097); Region: DUF4097; pfam13349 663951009787 1 probable transmembrane helix predicted for SATW20_19200 by TMHMM2.0 at aa 4-26 663951009788 Protein of unknown function (DUF1700); Region: DUF1700; pfam08006 663951009789 HMMPfam hit to PF08006, DUF1700, score 4.8e-121 663951009790 3 probable transmembrane helices predicted for SATW20_19210 by TMHMM2.0 at aa 81-103, 107-129 and 136-158 663951009791 Bacterial PH domain; Region: DUF304; cl01348 663951009792 1 probable transmembrane helix predicted for SATW20_19220 by TMHMM2.0 at aa 21-40 663951009793 Thiol-disulfide isomerase and thioredoxins [Posttranslational modification, protein turnover, chaperones / Energy production and conversion]; Region: TrxA; COG0526 663951009794 6 probable transmembrane helices predicted for SATW20_19240 by TMHMM2.0 at aa 21-38, 48-70, 102-124,139-161, 166-188 and 219-241 663951009795 ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131 663951009796 ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230 663951009797 Walker A/P-loop; other site 663951009798 ATP binding site [chemical binding]; other site 663951009799 Q-loop/lid; other site 663951009800 ABC transporter signature motif; other site 663951009801 Walker B; other site 663951009802 D-loop; other site 663951009803 H-loop/switch region; other site 663951009804 HMMPfam hit to PF00005, ABC_tran, score 7.2e-42 663951009805 PS00017 ATP/GTP-binding site motif A (P-loop). 663951009806 ABC-2 family transporter protein; Region: ABC2_membrane_5; pfam13346 663951009807 6 probable transmembrane helices predicted for SATW20_19260 by TMHMM2.0 at aa 13-32, 37-55, 87-109,119-141, 153-175 and 188-210 663951009808 ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131 663951009809 ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230 663951009810 Walker A/P-loop; other site 663951009811 ATP binding site [chemical binding]; other site 663951009812 Q-loop/lid; other site 663951009813 ABC transporter signature motif; other site 663951009814 Walker B; other site 663951009815 D-loop; other site 663951009816 H-loop/switch region; other site 663951009817 HMMPfam hit to PF00005, ABC_tran, score 1.9e-37 663951009818 PS00017 ATP/GTP-binding site motif A (P-loop). 663951009819 Predicted transcriptional regulators [Transcription]; Region: COG1725 663951009820 Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377 663951009821 DNA-binding site [nucleotide binding]; DNA binding site 663951009822 HMMPfam hit to PF00392, GntR, score 1.5e-18 663951009823 2 probable transmembrane helices predicted for SATW20_19290 by TMHMM2.0 at aa 7-24 and 34-51 663951009824 Aspartate/tyrosine/aromatic aminotransferase [Amino acid transport and metabolism]; Region: COG0436 663951009825 Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609 663951009826 pyridoxal 5'-phosphate binding site [chemical binding]; other site 663951009827 homodimer interface [polypeptide binding]; other site 663951009828 catalytic residue [active] 663951009829 HMMPfam hit to PF00155, Aminotran_1_2, score 3.8e-20 663951009830 MAP domain; Region: MAP; pfam03642 663951009831 MAP domain; Region: MAP; pfam03642 663951009832 MAP domain; Region: MAP; pfam03642 663951009833 MAP domain; Region: MAP; pfam03642 663951009834 MAP domain; Region: MAP; pfam03642 663951009835 MAP domain; Region: MAP; pfam03642 663951009836 HMMPfam hit to PF03642, MAP, score 3.3e-49 663951009837 HMMPfam hit to PF03642, MAP, score 1.9e-56 663951009838 HMMPfam hit to PF03642, MAP, score 1.8e-53 663951009839 HMMPfam hit to PF03642, MAP, score 1e-46 663951009840 HMMPfam hit to PF03642, MAP, score 1.9e-55 663951009841 HMMPfam hit to PF03642, MAP, score 7.1e-50 663951009842 Neutral sphingomyelinases (nSMase) catalyze the hydrolysis of sphingomyelin in biological membranes to ceramide and phosphorylcholine; Region: nSMase; cd09078 663951009843 putative catalytic site [active] 663951009844 metal binding site A [ion binding]; metal-binding site 663951009845 phosphate binding site [ion binding]; other site 663951009846 metal binding site C [ion binding]; metal-binding site 663951009847 metal binding site B [ion binding]; metal-binding site 663951009848 HMMPfam hit to PF03372, Exo_endo_phos, score 1.8e-36 663951009849 prophage phiSa3(TW20) 663951009850 1 probable transmembrane helix predicted for SATW20_19330 by TMHMM2.0 at aa 29-51 663951009851 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 663951009852 3 probable transmembrane helices predicted for SATW20_19340 by TMHMM2.0 at aa 7-29, 33-55 and 62-84 663951009853 PS00225 Crystallins beta and gamma 'Greek key' motif signature. 663951009854 3 probable transmembrane helices predicted for SATW20_19350 by TMHMM2.0 at aa 3-25, 35-57 and 62-84 663951009855 Staphylococcal complement inhibitor SCIN; Region: CompInhib_SCIN; pfam11546 663951009856 Bacterial SH3 domain; Region: SH3_5; pfam08460 663951009857 HMMPfam hit to PF08460, SH3_5, score 7.3e-08 663951009858 Staphylokinase/Streptokinase family; Region: Staphylokinase; pfam02821 663951009859 HMMPfam hit to PF02821, Staphylokinase, score 1.5e-38 663951009860 CHAP domain; Region: CHAP; pfam05257 663951009861 PS00017 ATP/GTP-binding site motif A (P-loop). 663951009862 HMMPfam hit to PF05257, CHAP, score 4.5e-38 663951009863 Small integral membrane protein [Function unknown]; Region: COG5546 663951009864 HMMPfam hit to PF04531, Phage_holin_1, score 6.2e-58 663951009865 1 probable transmembrane helix predicted for SATW20_19400 by TMHMM2.0 at aa 12-34 663951009866 Staphylococcal/Streptococcal toxin, OB-fold domain; Region: Stap_Strp_toxin; pfam01123 663951009867 Staphylococcal/Streptococcal toxin, beta-grasp domain; Region: Stap_Strp_tox_C; pfam02876 663951009868 HMMPfam hit to PF02876, Stap_Strp_tox_C, score 4.1e-74 663951009869 PS00278 Staphyloccocal enterotoxin/Streptococcal pyrogenic exotoxin signature 2. 663951009870 PS00277 Staphylococcal enterotoxin/Streptococcal pyrogenic exotoxin signature 1. 663951009871 HMMPfam hit to PF01123, Stap_Strp_toxin, score 8.7e-46 663951009872 Zinc finger-containing protein; Region: zf-C4H2; pfam10146 663951009873 Ligand-gated ion channel; Region: Lig_chan; pfam00060 663951009874 1 probable transmembrane helix predicted for SATW20_19420 by TMHMM2.0 at aa 98-120 663951009875 phage minor structural protein, N-terminal region; Region: put_anti_recept; TIGR01665 663951009876 mttA/Hcf106 family; Region: MttA_Hcf106; cl00788 663951009877 TolA protein; Region: tolA_full; TIGR02794 663951009878 Phage tail protein; Region: Sipho_tail; cl17486 663951009879 Phage tail protein; Region: Sipho_tail; cl17486 663951009880 Phage-related minor tail protein [Function unknown]; Region: COG5280 663951009881 The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature; Region: BAR; cl12013 663951009882 Phage-related protein [Function unknown]; Region: COG5412 663951009883 Polysaccharide biosynthesis protein; Region: Polysacc_synt_3; pfam13440 663951009884 Peptidase family M23; Region: Peptidase_M23; pfam01551 663951009885 Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane]; Region: NlpD; COG0739 663951009886 Lytic Transglycosylase (LT) and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL). LTs...; Region: LT_GEWL; cd00254 663951009887 N-acetyl-D-glucosamine binding site [chemical binding]; other site 663951009888 catalytic residue [active] 663951009889 HMMPfam hit to PF01464, SLT, score 0.00012 663951009890 HMMPfam hit to PF01551, Peptidase_M23, score 3.5e-35 663951009891 HMMPfam hit to PF05017, TMP, score 0.24 663951009892 6 probable transmembrane helices predicted for SATW20_19470 by TMHMM2.0 at aa 487-509, 516-538, 548-570,657-679, 694-716 and 735-757 663951009893 HMMPfam hit to PF05017, TMP, score 0.11 663951009894 Predicted helix-turn-helix motif with score 973.000,SD 2.50 at aa 407-428, sequence FSYQEFLKTIEDSQGTVNQTFK 663951009895 PS00017 ATP/GTP-binding site motif A (P-loop). 663951009896 phage major tail protein, phi13 family; Region: maj_tail_phi13; TIGR01603 663951009897 Bacterial surface proteins containing Ig-like domains [Cell motility and secretion]; Region: COG5492 663951009898 Bacterial Ig-like domain (group 2); Region: Big_2; pfam02368 663951009899 HMMPfam hit to PF02368, Big_2, score 2e-11 663951009900 Bacteriophage protein of unknown function (DUF646); Region: DUF646; pfam04883 663951009901 Translocation protein Sec62; Region: Sec62; cl02170 663951009902 Phage capsid family; Region: Phage_capsid; pfam05065 663951009903 Protease subunit of ATP-dependent Clp proteases [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: ClpP; COG0740 663951009904 Caseinolytic protease (ClpP) is an ATP-dependent, highly conserved serine protease; Region: S14_ClpP_1; cd07016 663951009905 oligomer interface [polypeptide binding]; other site 663951009906 active site residues [active] 663951009907 HMMPfam hit to PF00574, CLP_protease, score 1.5e-51 663951009908 phage portal protein, HK97 family; Region: portal_HK97; TIGR01537 663951009909 Phage-related protein [Function unknown]; Region: COG4695; cl01923 663951009910 HMMPfam hit to PF04860, Phage_portal, score 4.3e-85 663951009911 Phage terminase-like protein, large subunit [General function prediction only]; Region: COG4626 663951009912 HMMPfam hit to PF03354, Terminase_1, score 3.8e-26 663951009913 Restriction endonuclease [Defense mechanisms]; Region: McrA; COG1403 663951009914 HNH endonuclease; Region: HNH; pfam01844 663951009915 active site 663951009916 HMMPfam hit to PF01844, HNH, score 2e-07 663951009917 PS00190 Cytochrome c family heme-binding site signature. 663951009918 phage transcriptional activator, RinA family; Region: phage_rinA; TIGR01636 663951009919 Protein of unknown function (DUF1514); Region: DUF1514; pfam07438 663951009920 HMMPfam hit to PF07438, DUF1514, score 6.7e-50 663951009921 1 probable transmembrane helix predicted for SATW20_19640 by TMHMM2.0 at aa 4-21 663951009922 Transcriptional activator RinB; Region: RinB; pfam06116 663951009923 HMMPfam hit to PF06116, RinB, score 1.4e-34 663951009924 Protein of unknown function (DUF1523); Region: DUF1523; pfam07509 663951009925 1 probable transmembrane helix predicted for SATW20_19660 by TMHMM2.0 at aa 13-35 663951009926 Protein of unknown function (DUF1381); Region: DUF1381; pfam07129 663951009927 HMMPfam hit to PF07129, DUF1381, score 1.3e-37 663951009928 dUTPase; Region: dUTPase_2; pfam08761 663951009929 Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) MazG-like domain found in dimeric 2-Deoxyuridine 5'-triphosphate nucleotidohydrolase and similar proteins; Region: NTP-PPase_dUTPase; cd11527 663951009930 active site 663951009931 homodimer interface [polypeptide binding]; other site 663951009932 metal binding site [ion binding]; metal-binding site 663951009933 HMMPfam hit to PF08761, dUTPase_2, score 8e-13 663951009934 Protein of unknown function (DUF1024); Region: DUF1024; pfam06260 663951009935 HMMPfam hit to PF06260, DUF1024, score 8.2e-23 663951009936 YopX protein; Region: YopX; pfam09643 663951009937 Phage Conserved Open Reading Frame 51; Region: Phage_Orf51; pfam06194 663951009938 HMMPfam hit to PF06194, Phage_Orf51, score 2e-61 663951009939 Protein of unknwon function (DUF3310); Region: DUF3310; pfam11753 663951009940 PVL ORF-50-like family; Region: PVL_ORF50; pfam07768 663951009941 HMMPfam hit to PF07768, PVL_ORF50, score 7.1e-43 663951009942 Holliday junction resolvase [DNA replication, recombination, and repair]; Region: Rus; COG4570 663951009943 HMMPfam hit to PF05866, RusA, score 2e-53 663951009944 Putative primosome component and related proteins [DNA replication, recombination, and repair]; Region: DnaD; COG3935 663951009945 DnaD and phage-associated domain; Region: DnaD_dom; TIGR01446 663951009946 HMMPfam hit to PF04271, DnaD, score 3.8e-31 663951009947 Single-stranded DNA-binding protein [DNA replication, recombination, and repair]; Region: Ssb; COG0629 663951009948 SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496 663951009949 dimer interface [polypeptide binding]; other site 663951009950 ssDNA binding site [nucleotide binding]; other site 663951009951 tetramer (dimer of dimers) interface [polypeptide binding]; other site 663951009952 HMMPfam hit to PF00436, SSB, score 5.9e-36 663951009953 Metal-dependent hydrolases of the beta-lactamase superfamily I [General function prediction only]; Region: PhnP; COG1235 663951009954 Recombinational DNA repair protein (RecE pathway) [DNA replication, recombination, and repair]; Region: RecT; COG3723 663951009955 HMMPfam hit to PF03837, RecT, score 2.4e-72 663951009956 Chromosome segregation ATPases [Cell division and chromosome partitioning]; Region: Smc; COG1196 663951009957 PS00017 ATP/GTP-binding site motif A (P-loop). 663951009958 Protein of unknown function (DUF1108); Region: DUF1108; pfam06531 663951009959 HMMPfam hit to PF06531, DUF1108, score 1.1e-59 663951009960 Protein of unknown function (DUF1270); Region: DUF1270; pfam06900 663951009961 HMMPfam hit to PF06900, DUF1270, score 7.9e-39 663951009962 1 probable transmembrane helix predicted for SATW20_19860 by TMHMM2.0 at aa 7-29 663951009963 Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4707 663951009964 HMMPfam hit to PF05595, DUF771, score 4.2e-64 663951009965 AntA/AntB antirepressor; Region: AntA; cl01430 663951009966 Uncharacterized phage-encoded protein [Function unknown]; Region: COG3645 663951009967 HMMPfam hit to PF03374, ANT, score 2.7e-105 663951009968 HMMPfam hit to PF08346, AntA, score 3.9e-34 663951009969 Uncharacterized protein conserved in bacteria (DUF2064); Region: DUF2064; cl17492 663951009970 Protein of unknown function (DUF2829); Region: DUF2829; pfam11195 663951009971 Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396 663951009972 Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093 663951009973 non-specific DNA binding site [nucleotide binding]; other site 663951009974 salt bridge; other site 663951009975 sequence-specific DNA binding site [nucleotide binding]; other site 663951009976 HMMPfam hit to PF01381, HTH_3, score 8.2e-11 663951009977 Predicted helix-turn-helix motif with score 1869.000, SD 5.55 at aa 13-34, sequence LTQKELGDLFKVSSRTIQNMEK 663951009978 Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093 663951009979 non-specific DNA binding site [nucleotide binding]; other site 663951009980 salt bridge; other site 663951009981 sequence-specific DNA binding site [nucleotide binding]; other site 663951009982 Predicted transcriptional regulator [Transcription]; Region: COG2932 663951009983 Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529 663951009984 Catalytic site [active] 663951009985 HMMPfam hit to PF01381, HTH_3, score 1.4e-11 663951009986 Predicted helix-turn-helix motif with score 2092.000, SD 6.31 at aa 22-43, sequence MSQKKLAELINIKPSTLSDYLN 663951009987 HMMPfam hit to PF00717, Peptidase_S24, score 7e-21 663951009988 DNA polymerase III subunit epsilon; Validated; Region: PRK06195 663951009989 DnaQ-like (or DEDD) 3'-5' exonuclease domain superfamily; Region: DnaQ_like_exo; cl10012 663951009990 active site 663951009991 catalytic site [active] 663951009992 substrate binding site [chemical binding]; other site 663951009993 HMMPfam hit to PF00929, Exonuc_X-T, score 1.8e-06 663951009994 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 663951009995 Integrase [DNA replication, recombination, and repair]; Region: XerC; COG0582 663951009996 phiLC3 phage and phage-related integrases, site-specific recombinases, DNA breaking-rejoining enzymes, C-terminal catalytic domain. This CD includes various bacterial (mainly gram positive) and phage integrases, including those similar to Lactococcus...; Region: INT_phiLC3_C; cd01189 663951009997 Int/Topo IB signature motif; other site 663951009998 HMMPfam hit to PF00589, Phage_integrase, score 9.1e-15 663951009999 Leukocidin/Hemolysin toxin family; Region: Leukocidin; pfam07968 663951010000 HMMPfam hit to PF07968, Leukocidin, score 3.8e-124 663951010001 PS00340 Growth factor and cytokines receptors family signature 2. 663951010002 Leukocidin/Hemolysin toxin family; Region: Leukocidin; pfam07968 663951010003 HMMPfam hit to PF07968, Leukocidin, score 1.5e-111 663951010004 1 probable transmembrane helix predicted for SATW20_20020 by TMHMM2.0 at aa 7-24 663951010005 succinyl-diaminopimelate desuccinylase; Reviewed; Region: PRK08588 663951010006 Peptidase M20 acetylornithine deacetylase/succinyl-diaminopimelate desuccinylase (ArgE/DapE)-like; Region: M20_ArgE_DapE_like; cd08659 663951010007 metal binding site [ion binding]; metal-binding site 663951010008 dimer interface [polypeptide binding]; other site 663951010009 PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 663951010010 HMMPfam hit to PF01546, Peptidase_M20, score 2.3e-42 663951010011 HMMPfam hit to PF07687, M20_dimer, score 3.7e-26 663951010012 CDS contains a frameshift after codon 34. Frameshift occurs at a poly A heptamer 663951010013 Periplasmic binding protein FeuA. These proteins have predicted to function as initial receptors in ABC transport of metal ions in some eubacterial species. They belong to the TroA superfamily of periplasmic metal binding proteins that share a distinct...; Region: FeuA; cd01138 663951010014 Periplasmic binding protein; Region: Peripla_BP_2; pfam01497 663951010015 putative ligand binding residues [chemical binding]; other site 663951010016 HMMPfam hit to PF01497, Peripla_BP_2, score 1.3e-28 663951010017 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 663951010018 Cation transport protein; Region: TrkH; cl17365 663951010019 Trk-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: TrkG; COG0168 663951010020 11 probable transmembrane helices predicted for SATW20_20070 by TMHMM2.0 at aa 7-29, 71-93, 123-145,155-177, 184-206, 221-240, 270-292, 297-319, 339-361,365-384 and 397-419 663951010021 HMMPfam hit to PF02386, TrkH, score 9.4e-75 663951010022 N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301 663951010023 Coenzyme A binding pocket [chemical binding]; other site 663951010024 HMMPfam hit to PF00583, Acetyltransf_1, score 2.8e-08 663951010025 3 probable transmembrane helices predicted for SATW20_20090 by TMHMM2.0 at aa 21-43, 71-88 and 95-112 663951010026 Phage terminase, small subunit [DNA replication, recombination, and repair]; Region: XtmA; COG3728 663951010027 HMMPfam hit to PF03592, Terminase_2, score 1.8e-75 663951010028 Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cl17257 663951010029 chaperonin GroEL; Reviewed; Region: groEL; PRK12849 663951010030 GroEL_like type I chaperonin. Chaperonins are involved in productive folding of proteins. They share a common general morphology, a double toroid of 2 stacked rings, each composed of 7-9 subunits. The symmetry of type I is seven-fold and they are found...; Region: GroEL; cd03344 663951010031 ring oligomerisation interface [polypeptide binding]; other site 663951010032 ATP/Mg binding site [chemical binding]; other site 663951010033 stacking interactions; other site 663951010034 hinge regions; other site 663951010035 HMMPfam hit to PF00118, Cpn60_TCP1, score 1.2e-195 663951010036 PS00296 Chaperonins cpn60 signature. 663951010037 Chaperonin 10 Kd subunit (cpn10 or GroES); Cpn10 cooperates with chaperonin 60 (cpn60 or GroEL), an ATPase, to assist the folding and assembly of proteins and is found in eubacterial cytosol, as well as in the matrix of mitochondria and chloroplasts. It...; Region: cpn10; cd00320 663951010038 oligomerisation interface [polypeptide binding]; other site 663951010039 mobile loop; other site 663951010040 roof hairpin; other site 663951010041 HMMPfam hit to PF00166, Cpn10, score 7.8e-50 663951010042 PS00681 Chaperonins cpn10 signature. 663951010043 CAAX protease self-immunity; Region: Abi; pfam02517 663951010044 6 probable transmembrane helices predicted for SATW20_20140 by TMHMM2.0 at aa 5-25, 40-62, 82-104,119-141, 162-180 and 185-202 663951010045 HMMPfam hit to PF02517, Abi, score 6.6e-23 663951010046 1 probable transmembrane helix predicted for SATW20_20150 by TMHMM2.0 at aa 386-405 663951010047 Nitroreductase-like family 4. A subfamily of the nitroreductase family containing uncharacterized proteins that are similar to nitroreductase. Nitroreductase catalyzes the reduction of nitroaromatic compounds such as nitrotoluenes, nitrofurans and...; Region: Nitroreductase_4; cd02140 663951010048 dimer interface [polypeptide binding]; other site 663951010049 FMN binding site [chemical binding]; other site 663951010050 HMMPfam hit to PF00881, Nitroreductase, score 0.00039 663951010051 Predicted amidohydrolase [General function prediction only]; Region: COG0388 663951010052 Uncharacterized subgroup of the nitrilase superfamily (putative class 13 nitrilases); Region: nitrilase_5; cd07583 663951010053 putative active site [active] 663951010054 catalytic triad [active] 663951010055 putative dimer interface [polypeptide binding]; other site 663951010056 HMMPfam hit to PF00795, CN_hydrolase, score 4.6e-26 663951010057 PS01227 Uncharacterized protein family UPF0012 signature. 663951010058 delta-hemolysin; Provisional; Region: PRK14752 663951010059 HMMPfam hit to PF05372, Delta_lysin, score 1.5e-15 663951010060 Accessory gene regulator B; Region: AgrB; smart00793 663951010061 HMMPfam hit to PF04647, AgrB, score 3.2e-89 663951010062 5 probable transmembrane helices predicted for SATW20_20190 by TMHMM2.0 at aa 47-69, 81-100, 104-123,143-160 and 165-184 663951010063 Staphylococcal AgrD protein; Region: AgrD; smart00794 663951010064 HMMPfam hit to PF05931, AgrD, score 1.4e-25 663951010065 Predicted signal transduction protein with a C-terminal ATPase domain [Signal transduction mechanisms]; Region: COG2972 663951010066 Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075 663951010067 Mg2+ binding site [ion binding]; other site 663951010068 G-X-G motif; other site 663951010069 6 probable transmembrane helices predicted for SATW20_20210 by TMHMM2.0 at aa 7-29, 49-71, 78-100,110-132, 145-167 and 182-204 663951010070 HMMPfam hit to PF02518, HATPase_c, score 1e-06 663951010071 Response regulator of the LytR/AlgR family [Transcription / Signal transduction mechanisms]; Region: LytT; COG3279 663951010072 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 663951010073 active site 663951010074 phosphorylation site [posttranslational modification] 663951010075 intermolecular recognition site; other site 663951010076 dimerization interface [polypeptide binding]; other site 663951010077 LytTr DNA-binding domain; Region: LytTR; pfam04397 663951010078 HMMPfam hit to PF00072, Response_reg, score 4.3e-30 663951010079 HMMPfam hit to PF04397, LytTR, score 3.8e-20 663951010080 Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524 663951010081 Fructokinases (FRKs) mainly from bacteria and plants are enzymes with high specificity for fructose, as are all FRKs, but they catalyzes the conversion of fructose to fructose-6-phosphate, which is an entry point into glycolysis via conversion into...; Region: bac_FRK; cd01167 663951010082 putative substrate binding site [chemical binding]; other site 663951010083 putative ATP binding site [chemical binding]; other site 663951010084 HMMPfam hit to PF00294, PfkB, score 8e-105 663951010085 PS00584 pfkB family of carbohydrate kinases signature 2. 663951010086 PS00583 pfkB family of carbohydrate kinases signature 1. 663951010087 Beta-fructosidases (levanase/invertase) [Carbohydrate transport and metabolism]; Region: SacC; COG1621 663951010088 Glycosyl hydrolase family 32, beta-fructosidases; Region: GH32_B_Fructosidase; cd08996 663951010089 substrate binding [chemical binding]; other site 663951010090 active site 663951010091 Glycosyl hydrolases family 32 C terminal; Region: Glyco_hydro_32C; pfam08244 663951010092 HMMPfam hit to PF08244, Glyco_hydro_32C, score 9.5e-16 663951010093 HMMPfam hit to PF00251, Glyco_hydro_32N, score 7.4e-155 663951010094 PS00609 Glycosyl hydrolases family 32 active site. 663951010095 Transcriptional regulators [Transcription]; Region: PurR; COG1609 663951010096 Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392 663951010097 DNA binding site [nucleotide binding] 663951010098 domain linker motif; other site 663951010099 Ligand-binding domain of DNA transcription repressor specific for trehalose (TreR) which is a member of the LacI-GalR family of bacterial transcription regulators; Region: PBP1_TreR_like; cd01542 663951010100 dimerization interface [polypeptide binding]; other site 663951010101 ligand binding site [chemical binding]; other site 663951010102 HMMPfam hit to PF00532, Peripla_BP_1, score 0.00071 663951010103 HMMPfam hit to PF00356, LacI, score 3e-10 663951010104 Predicted helix-turn-helix motif with score 2286.000, SD 6.97 at aa 2-23, sequence KNISDIAKLAGVSKSTVSRFLN 663951010105 PS00356 Bacterial regulatory proteins, lacI family signature. 663951010106 Ammonia permease [Inorganic ion transport and metabolism]; Region: AmtB; COG0004 663951010107 HMMPfam hit to PF00909, Ammonium_transp, score 9.3e-142 663951010108 11 probable transmembrane helices predicted for SATW20_20260 by TMHMM2.0 at aa 6-28, 48-70, 95-117,124-146, 156-178, 190-212, 222-244, 253-272, 276-298,310-329 and 349-371 663951010109 SirA, YedF, and YeeD. Two-layered alpha/beta sandwich domain. SirA (also known as UvrY, and YhhP) belongs to a family of bacterial two-component response regulators that controls secondary metabolism and virulence. The other member of this...; Region: SirA_YedF_YeeD; cd00291 663951010110 CPxP motif; other site 663951010111 HMMPfam hit to PF01206, SirA, score 2.5e-25 663951010112 HMMPfam hit to PF04143, DUF395, score 4e-18 663951010113 9 probable transmembrane helices predicted for SATW20_20280 by TMHMM2.0 at aa 4-18, 39-61, 71-93, 105-127,147-169, 199-218, 248-267, 288-310 and 320-339 663951010114 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 663951010115 HMMPfam hit to PF04143, DUF395, score 8.1e-18 663951010116 Prophage phiSPbeta-like(TW20) 663951010117 Site-specific recombinases, DNA invertase Pin homologs [DNA replication, recombination, and repair]; Region: PinR; COG1961 663951010118 Serine Recombinase family, catalytic domain; a DNA binding domain may be present either N- or C-terminal to the catalytic domain. These enzymes perform site-specific recombination of DNA molecules by a concerted, four-strand cleavage and rejoining...; Region: Ser_Recombinase; cd00338 663951010119 catalytic residues [active] 663951010120 catalytic nucleophile [active] 663951010121 Recombinase; Region: Recombinase; pfam07508 663951010122 HMMPfam hit to PF07508, Recombinase, score 6.1e-16 663951010123 HMMPfam hit to PF00239, Resolvase, score 3.6e-18 663951010124 Myb-like DNA-binding domain; Region: Myb_DNA-bind_6; pfam13921 663951010125 DNA binding site [nucleotide binding] 663951010126 HMMPfam hit to PF00249, Myb_DNA-binding, score 0.16 663951010127 PS00037 Myb DNA-binding domain repeat signature 1. 663951010128 HMMPfam hit to PF00249, Myb_DNA-binding, score 0.00086 663951010129 PS00037 Myb DNA-binding domain repeat signature 1. 663951010130 Endodeoxyribonuclease RusA; Region: RusA; pfam05866 663951010131 HMMPfam hit to PF05866, RusA, score 0.00062 663951010132 Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) MazG-like domain found in Exiguobacterium sibiricum YP_001813558.1 protein and its bacterial homologs; Region: NTP-PPase_YP_001813558; cd11545 663951010133 putative nucleotide binding site [chemical binding]; other site 663951010134 putative metal binding site [ion binding]; other site 663951010135 TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947 663951010136 catalytic residues [active] 663951010137 HMMPfam hit to PF00462, Glutaredoxin, score 8.7e-06 663951010138 hypothetical protein; Provisional; Region: PRK01184 663951010139 ribonucleotide-diphosphate reductase subunit beta; Provisional; Region: nrdF2; PRK13966 663951010140 Ribonucleotide Reductase, R2/beta subunit, ferritin-like diiron-binding domain; Region: RNRR2; cd01049 663951010141 dimer interface [polypeptide binding]; other site 663951010142 putative radical transfer pathway; other site 663951010143 diiron center [ion binding]; other site 663951010144 tyrosyl radical; other site 663951010145 HMMPfam hit to PF00268, Ribonuc_red_sm, score 5.1e-23 663951010146 1 probable transmembrane helix predicted for SATW20_20380 by TMHMM2.0 at aa 156-178 663951010147 Ribonucleotide reductase N-terminal; Region: RNR_N; pfam08343 663951010148 Ribonucleotide reductase and Pyruvate formate lyase; Region: RNR_PFL; cl09939 663951010149 Hedgehog/Intein domain, found in Hedgehog proteins as well as proteins which contain inteins and undergo protein splicing (e.g. DnaB, RIR1-2, GyrA and Pol). In protein splicing an intervening polypeptide sequence - the intein - is excised from a protein; Region: Hint; cd00081 663951010150 protein-splicing catalytic site; other site 663951010151 thioester formation/cholesterol transfer; other site 663951010152 Intein/homing endonuclease [DNA replication, recombination, and repair]; Region: COG1372 663951010153 Hint (Hedgehog/Intein) domain C-terminal region; Region: HintC; smart00305 663951010154 Ribonucleotide reductase, barrel domain; Region: Ribonuc_red_lgC; pfam02867 663951010155 HMMPfam hit to PF02867, Ribonuc_red_lgC, score 5.5e-12 663951010156 HMMPfam hit to PF02867, Ribonuc_red_lgC, score 4.5e-14 663951010157 PS00089 Ribonucleotide reductase large subunit signature. 663951010158 intein 663951010159 HMMPfam hit to PF00317, Ribonuc_red_lgN, score 1.5e-18 663951010160 HMMPfam hit to PF08343, RNR_N, score 5.1e-28 663951010161 NrdI Flavodoxin like; Region: Flavodoxin_NdrI; pfam07972 663951010162 HMMPfam hit to PF07972, Flavodoxin_NdrI, score 1.7e-41 663951010163 Siphovirus Gp157; Region: Sipho_Gp157; pfam05565 663951010164 HMMPfam hit to PF05565, Sipho_Gp157, score 6e-16 663951010165 hypothetical protein; Region: PHA02246 663951010166 6 probable transmembrane helices predicted for SATW20_20460 by TMHMM2.0 at aa 2-24, 34-56, 63-85, 91-113,146-168 and 172-194 663951010167 2 probable transmembrane helices predicted for SATW20_20470 by TMHMM2.0 at aa 9-31 and 46-63 663951010168 Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group...; Region: Cyt_C5_DNA_methylase; cd00315 663951010169 C-5 cytosine-specific DNA methylase; Region: DNA_methylase; pfam00145 663951010170 cofactor binding site; other site 663951010171 DNA binding site [nucleotide binding] 663951010172 substrate interaction site [chemical binding]; other site 663951010173 HMMPfam hit to PF00145, DNA_methylase, score 2.7e-43 663951010174 S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440 663951010175 S-adenosylmethionine binding site [chemical binding]; other site 663951010176 HMMPfam hit to PF08241, Methyltransf_11, score 6.2e-08 663951010177 Nucleoside 2-deoxyribosyltransferase; Region: Nuc_deoxyrib_tr; cl17818 663951010178 1 probable transmembrane helix predicted for SATW20_20600 by TMHMM2.0 at aa 13-32 663951010179 DNA ligase; Provisional; Region: 30; PHA02587 663951010180 Adenylation domain of kDNA ligases and similar proteins; Region: Adenylation_kDNA_ligase_like; cd07896 663951010181 DNA binding site [nucleotide binding] 663951010182 active site 663951010183 The Oligonucleotide/oligosaccharide binding (OB)-fold domain of kDNA ligase-like ATP-dependent DNA ligases is a DNA-binding module that is part of the catalytic core unit; Region: OBF_kDNA_ligase_like; cd08041 663951010184 DNA binding site [nucleotide binding] 663951010185 HMMPfam hit to PF01068, DNA_ligase_A_M, score 1.4e-06 663951010186 CDS contains a frameshift and insertion after codon 473. Similar to Bacillus subtilis DNA polymerase YorL UniProt:O31902 (EMBL:Z99114) (1305 aa) fasta scores: E()=0,46.066% id in 1309 aa 663951010187 HMMPfam hit to PF07733, DNA_pol3_alpha, score 1.5e-12 663951010188 HMMPfam hit to PF07733, DNA_pol3_alpha, score 7.5e-24 663951010189 HMMPfam hit to PF02811, PHP, score 1.1e-25 663951010190 Probable gene remnant. CDS lacks appropriate translational start site 663951010191 CDS is disrupted by the insertion of the IS256 element 663951010192 HMMPfam hit to PF01872, RibD_C, score 4.1e-11 663951010193 Transposase, Mutator family; Region: Transposase_mut; pfam00872 663951010194 MULE transposase domain; Region: MULE; pfam10551 663951010195 HMMPfam hit to PF00872, Transposase_mut, score 9.8e-228 663951010196 PS01007 Transposases, Mutator family, signature. 663951010197 Acetyltransferase (GNAT) domain; Region: Acetyltransf_8; pfam13523 663951010198 Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583 663951010199 Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs)...; Region: APH_ChoK_like; cd05120 663951010200 Phosphotransferase enzyme family; Region: APH; pfam01636 663951010201 active site 663951010202 ATP binding site [chemical binding]; other site 663951010203 Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs)...; Region: APH_ChoK_like; cl17270 663951010204 substrate binding site [chemical binding]; other site 663951010205 HMMPfam hit to PF01636, APH, score 4.6e-26 663951010206 HMMPfam hit to PF00583, Acetyltransf_1, score 1.6e-16 663951010207 Histone acetyltransferase HPA2 and related acetyltransferases [Transcription / General function prediction only]; Region: WecD; COG0454 663951010208 N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301 663951010209 Coenzyme A binding pocket [chemical binding]; other site 663951010210 HMMPfam hit to PF00583, Acetyltransf_1, score 7.2e-22 663951010211 Transposase, Mutator family; Region: Transposase_mut; pfam00872 663951010212 MULE transposase domain; Region: MULE; pfam10551 663951010213 HMMPfam hit to PF00872, Transposase_mut, score 9.8e-228 663951010214 PS01007 Transposases, Mutator family, signature. 663951010215 Probable gene remnant. Similar to the N-terminal region of Staphylococcus aureus uncharacterized protein UniProt:O54362 (EMBL:U73027) (154 aa) fasta scores: E()=3.6e-23, 100.0% id in 60 aa 663951010217 HMMPfam hit to PF08279, HTH_11, score 3.8e-21 663951010218 Predicted helix-turn-helix motif with score 1909.000, SD 5.69 at aa 20-41, sequence IPAKEIAQRFNISLRTVYRDIR 663951010219 Aminoglycoside 3'-phosphotransferase (APH). The APH subfamily is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs), RIO kinases, actin-fragmin...; Region: APH; cd05150 663951010220 active site 663951010221 ATP binding site [chemical binding]; other site 663951010222 Phosphotransferase enzyme family; Region: APH; pfam01636 663951010223 antibiotic binding site [chemical binding]; other site 663951010224 HMMPfam hit to PF01636, APH, score 2.3e-42 663951010225 CDS contains frameshift resulting an insertion of 124 bp after codon 71. Similar to Enterococcus faecium (Streptococcus faecium) streptothricin acetyltransferase UniProt:Q7BFR8 (EMBL:AF330699) (180 aa) fasta scores: E()=4e-81, 99.444% id in 180 aa 663951010226 HMMPfam hit to PF00583, Acetyltransf_1, score 4.4e-25 663951010227 Probable gene remnant. Similar to the N-terminal region of Bacillus subtilis aminoglycoside 6-adenylyltransferase UniProt:P17585 (EMBL:M26879) (284 aa) fasta scores: E()=1.9e-41, 51.7% id in 176 aa 663951010228 HMMPfam hit to PF04439, Adenyl_transf, score 9.4e-82 663951010229 PS00017 ATP/GTP-binding site motif A (P-loop). 663951010230 1 probable transmembrane helix predicted for SATW20_20790 by TMHMM2.0 at aa 12-34 663951010231 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 663951010232 metallophosphatase superfamily, metallophosphatase domain; Region: MPP_superfamily; cl13995 663951010233 active site 663951010234 metal binding site [ion binding]; metal-binding site 663951010235 HMMPfam hit to PF00149, Metallophos, score 1e-10 663951010236 2 probable transmembrane helices predicted for SATW20_20820 by TMHMM2.0 at aa 5-27 and 42-60 663951010237 3 probable transmembrane helices predicted for SATW20_20830 by TMHMM2.0 at aa 4-21, 41-60 and 70-92 663951010238 Fic/DOC family; Region: Fic; cl00960 663951010239 HMMPfam hit to PF05012, DOC, score 1.6e-16 663951010240 Antidote-toxin recognition MazE; Region: Antitoxin-MazE; cl00877 663951010241 HMMPfam hit to PF04014, SpoVT_AbrB, score 0.0015 663951010242 Aquifex aeolicus AQ1575 and related proteins, metallophosphatase domain; Region: MPP_AQ1575; cd07390 663951010243 putative active site [active] 663951010244 putative metal binding site [ion binding]; other site 663951010245 HMMPfam hit to PF00149, Metallophos, score 0.00022 663951010246 Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149 663951010247 phosphoprotein phosphatases of the metallophosphatase superfamily, metallophosphatase domain; Region: MPP_PPP_family; cd00144 663951010248 active site 663951010249 metal binding site [ion binding]; metal-binding site 663951010250 HMMPfam hit to PF00149, Metallophos, score 5.1e-16 663951010251 PS00678 Trp-Asp (WD) repeats signature. 663951010252 VHS, ENTH and ANTH domain superfamily; composed of proteins containing a VHS, ENTH or ANTH domain. The VHS domain is present in Vps27 (Vacuolar Protein Sorting), Hrs (Hepatocyte growth factor-regulated tyrosine kinase substrate) and STAM (Signal...; Region: VHS_ENTH_ANTH; cl02544 663951010253 Asp-tRNAAsn/Glu-tRNAGln amidotransferase B subunit (PET112 homolog) [Translation, ribosomal structure and biogenesis]; Region: GatB; COG0064 663951010254 Transcriptional activator RinB; Region: RinB; pfam06116 663951010255 Restriction alleviation protein Lar; Region: Lar_restr_allev; pfam14354 663951010256 Staphylococcal nuclease homologues. SNase homologues are found in bacteria, archaea, and eukaryotes. They contain no disufide bonds; Region: SNc; cl00140 663951010257 Catalytic site; other site 663951010258 HMMPfam hit to PF00565, SNase, score 3.7e-06 663951010259 YopX protein; Region: YopX; cl09859 663951010260 Metallo-beta-lactamase superfamily; Region: Lactamase_B; cl00446 663951010261 HMMPfam hit to PF00753, Lactamase_B, score 2.1e-09 663951010262 single-stranded-DNA-specific exonuclease RecJ; Region: recJ; TIGR00644 663951010263 DHH family; Region: DHH; pfam01368 663951010264 HMMPfam hit to PF01368, DHH, score 7.5e-27 663951010265 hypothetical protein; Provisional; Region: PRK08624 663951010266 TOPRIM_DnaG_primases: The topoisomerase-primase (TORPIM) nucleotidyl transferase/hydrolase domain found in the active site regions of proteins similar to Escherichia coli DnaG. Primases synthesize RNA primers for the initiation of DNA replication. DnaG...; Region: TOPRIM_DnaG_primases; cd03364 663951010267 active site 663951010268 metal binding site [ion binding]; metal-binding site 663951010269 interdomain interaction site; other site 663951010270 Replicative DNA helicase [DNA replication, recombination, and repair]; Region: DnaB; COG0305 663951010271 DnaB-like helicase N terminal domain; Region: DnaB; pfam00772 663951010272 RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233 663951010273 ATP binding site [chemical binding]; other site 663951010274 Walker B motif; other site 663951010275 Predicted helix-turn-helix motif with score 1118.000, SD 2.99 at aa 229-250, sequence KSRTSLGEATDLAINRWYNWET 663951010276 AAA domain; Region: AAA_24; pfam13479 663951010277 PS00017 ATP/GTP-binding site motif A (P-loop). 663951010278 acetyacetyl-CoA reductase; Provisional; Region: PRK12938 663951010279 DNA-sulfur modification-associated; Region: DndB; cl17621 663951010280 Phage integrase, N-terminal SAM-like domain; Region: Phage_integr_N; cl12235 663951010281 DNA breaking-rejoining enzymes, intergrase/recombinases, C-terminal catalytic domain. The tyrosine recombinase/integrase family share the same catalytic domain containing six conserved active site residues. The best-studied members of this diverse family...; Region: INT_REC_C; cd01182 663951010282 active site 663951010283 catalytic residues [active] 663951010284 DNA binding site [nucleotide binding] 663951010285 Int/Topo IB signature motif; other site 663951010286 HMMPfam hit to PF00589, Phage_integrase, score 3.4e-05 663951010287 HMMPfam hit to PF02899, Phage_integr_N, score 1e-05 663951010288 CDS is disrupted by the insertion of an IS element after codon 43. Similar to Staphylococcus epidermidis (strain ATCC 35984/RP62A) conserved domain protein UniProt:Q5HMM3 (EMBL:CP000029) (150 aa) fasta scores: E()=8.7e-52, 92.667% id in 150 aa 663951010289 Transposase, Mutator family; Region: Transposase_mut; pfam00872 663951010290 MULE transposase domain; Region: MULE; pfam10551 663951010291 HMMPfam hit to PF00872, Transposase_mut, score 9.8e-228 663951010292 PS01007 Transposases, Mutator family, signature. 663951010293 Antirestriction protein (ArdA); Region: ArdA; cl01953 663951010294 HMMPfam hit to PF07275, ArdA, score 6.3e-06 663951010295 1 probable transmembrane helix predicted for SATW20_21440 by TMHMM2.0 at aa 2-19 663951010296 AAA domain; Region: AAA_30; pfam13604 663951010297 Family description; Region: UvrD_C_2; pfam13538 663951010298 PS00017 ATP/GTP-binding site motif A (P-loop). 663951010299 Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591 663951010300 IHF dimer interface [polypeptide binding]; other site 663951010301 IHF - DNA interface [nucleotide binding]; other site 663951010302 HMMPfam hit to PF00216, Bac_DNA_binding, score 3.8e-07 663951010303 YonK protein; Region: YonK; pfam09642 663951010304 PS00339 Aminoacyl-transfer RNA synthetases class-II signature 2. 663951010305 large terminase protein; Provisional; Region: 17; PHA02533 663951010306 Terminase-like family; Region: Terminase_6; pfam03237 663951010307 PS00017 ATP/GTP-binding site motif A (P-loop). 663951010308 PS00030 Eukaryotic putative RNA-binding region RNP-1 signature. 663951010309 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 663951010310 Phage integrase, N-terminal SAM-like domain; Region: Phage_integr_N2; pfam13495 663951010311 tyrosine recombinase XerC; Region: recomb_XerC; TIGR02224 663951010312 DNA breaking-rejoining enzymes, intergrase/recombinases, C-terminal catalytic domain. The tyrosine recombinase/integrase family share the same catalytic domain containing six conserved active site residues. The best-studied members of this diverse family...; Region: INT_REC_C; cd01182 663951010313 active site 663951010314 catalytic residues [active] 663951010315 DNA binding site [nucleotide binding] 663951010316 Int/Topo IB signature motif; other site 663951010317 HMMPfam hit to PF00589, Phage_integrase, score 0.0015 663951010318 phage tail tape measure protein, TP901 family, core region; Region: tape_meas_TP901; TIGR01760 663951010319 Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane]; Region: NlpD; COG0739 663951010320 Peptidase family M23; Region: Peptidase_M23; pfam01551 663951010321 ATPase involved in DNA repair [DNA replication, recombination, and repair]; Region: SbcC; COG0419 663951010322 Predicted helix-turn-helix motif with score 1243.000, SD 3.42 at aa 1233-1254, sequence KGIMQAAKAANMSKSQMKDLKK 663951010323 PS00017 ATP/GTP-binding site motif A (P-loop). 663951010324 Predicted helix-turn-helix motif with score 1303.000, SD 3.62 at aa 1605-1626, sequence EKTKEKAEEAGVTVKQLYKQFT 663951010325 PS00287 Cysteine proteases inhibitors signature. 663951010326 HMMPfam hit to PF01551, Peptidase_M23, score 3.4e-20 663951010327 chromosome segregation protein SMC, common bacterial type; Region: SMC_prok_B; TIGR02168 663951010328 Chromosome segregation ATPases [Cell division and chromosome partitioning]; Region: Smc; COG1196 663951010329 Phage-related protein [Function unknown]; Region: PblB; COG4926 663951010330 Chaperone of endosialidase; Region: Peptidase_S74; pfam13884 663951010331 PS00402 Binding-protein-dependent transport systems inner membrane comp. sign. 663951010332 4 probable transmembrane helices predicted for SATW20_21770 by TMHMM2.0 at aa 20-42, 68-90, 97-119 and 132-150 663951010333 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 663951010334 1 probable transmembrane helix predicted for SATW20_21780 by TMHMM2.0 at aa 146-168 663951010335 Phage lysis protein, holin; Region: Phage_holin; pfam04688 663951010336 2 probable transmembrane helices predicted for SATW20_21790 by TMHMM2.0 at aa 7-24 and 39-57 663951010337 HMMPfam hit to PF04688, Phage_holin, score 1.8e-09 663951010338 CHAP domain; Region: CHAP; pfam05257 663951010339 N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696 663951010340 active site 663951010341 metal binding site [ion binding]; metal-binding site 663951010342 HMMPfam hit to PF05257, CHAP, score 2.9e-07 663951010343 HMMPfam hit to PF01520, Amidase_3, score 1.2e-05 663951010344 HMMPfam hit to PF00746, Gram_pos_anchor, score 0.00017 663951010345 2 probable transmembrane helices predicted for SATW20_21850 by TMHMM2.0 at aa 7-29 and 178-197 663951010346 PS00343 Gram-positive cocci surface proteins 'anchoring' hexapeptide. 663951010347 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 663951010348 AT-rich DNA-binding protein [General function prediction only]; Region: COG2344 663951010349 Putative DNA-binding protein N-terminus; Region: Put_DNA-bind_N; pfam06971 663951010350 CoA binding domain; Region: CoA_binding; pfam02629 663951010351 HMMPfam hit to PF02629, CoA_binding, score 3e-36 663951010352 HMMPfam hit to PF06971, Put_DNA-bind_N, score 8.2e-27 663951010353 ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only]; Region: Uup; COG0488 663951010354 ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221 663951010355 ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221 663951010356 ABC transporter; Region: ABC_tran_2; pfam12848 663951010357 ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221 663951010358 HMMPfam hit to PF00005, ABC_tran, score 6.4e-48 663951010359 PS00017 ATP/GTP-binding site motif A (P-loop). 663951010360 PS00211 ABC transporters family signature. 663951010361 HMMPfam hit to PF00005, ABC_tran, score 2.1e-42 663951010362 PS00017 ATP/GTP-binding site motif A (P-loop). 663951010363 PS00211 ABC transporters family signature. 663951010364 Mismatch repair ATPase (MutS family) [DNA replication, recombination, and repair]; Region: MutS; COG0249 663951010365 ATP-binding cassette domain of MutS-like homolog; Region: ABC_MutS-like; cd03283 663951010366 Walker A/P-loop; other site 663951010367 ATP binding site [chemical binding]; other site 663951010368 Q-loop/lid; other site 663951010369 ABC transporter signature motif; other site 663951010370 Walker B; other site 663951010371 D-loop; other site 663951010372 H-loop/switch region; other site 663951010373 2 probable transmembrane helices predicted for SATW20_21880 by TMHMM2.0 at aa 5-27 and 159-181 663951010374 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 663951010375 HMMPfam hit to PF00488, MutS_V, score 4.7e-13 663951010376 PS00017 ATP/GTP-binding site motif A (P-loop). 663951010377 UGMP family protein; Validated; Region: PRK09604 663951010378 tRNA threonylcarbamoyl adenosine modification protein YeaZ; Region: T6A_YeaZ; TIGR03725 663951010379 HMMPfam hit to PF00814, Peptidase_M22, score 7.6e-77 663951010380 PS01016 Glycoprotease family signature. 663951010381 ribosomal-protein-alanine acetyltransferase; Region: rimI; TIGR01575 663951010382 N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301 663951010383 Coenzyme A binding pocket [chemical binding]; other site 663951010384 HMMPfam hit to PF00583, Acetyltransf_1, score 1.3e-17 663951010385 tRNA threonylcarbamoyl adenosine modification protein YeaZ; Region: T6A_YeaZ; TIGR03725 663951010386 Glycoprotease family; Region: Peptidase_M22; pfam00814 663951010387 HMMPfam hit to PF00814, Peptidase_M22, score 2.5e-64 663951010388 Predicted ATPase or kinase [General function prediction only]; Region: COG0802 663951010389 HMMPfam hit to PF02367, UPF0079, score 1.4e-43 663951010390 PS00017 ATP/GTP-binding site motif A (P-loop). 663951010391 dihydroxy-acid dehydratase; Provisional; Region: PRK00911 663951010392 6-phosphogluconate dehydratase; Region: edd; TIGR01196 663951010393 HMMPfam hit to PF00920, ILVD_EDD, score 0 663951010394 PS00886 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1. 663951010395 PS00887 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 2. 663951010396 acetolactate synthase catalytic subunit; Reviewed; Region: PRK07710 663951010397 Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035 663951010398 PYR/PP interface [polypeptide binding]; other site 663951010399 dimer interface [polypeptide binding]; other site 663951010400 TPP binding site [chemical binding]; other site 663951010401 Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205 663951010402 Thiamine pyrophosphate (TPP) family, Acetohydroxyacid synthase (AHAS) subfamily, TPP-binding module; composed of proteins similar to the large catalytic subunit of AHAS. AHAS catalyzes the condensation of two molecules of pyruvate to give the...; Region: TPP_AHAS; cd02015 663951010403 TPP-binding site [chemical binding]; other site 663951010404 dimer interface [polypeptide binding]; other site 663951010405 HMMPfam hit to PF02776, TPP_enzyme_N, score 1.3e-88 663951010406 HMMPfam hit to PF00205, TPP_enzyme_M, score 3.7e-61 663951010407 HMMPfam hit to PF02775, TPP_enzyme_C, score 4.1e-79 663951010408 PS00187 Thiamine pyrophosphate enzymes signature. 663951010410 HMMPfam hit to PF01842, ACT, score 2e-05 663951010411 ketol-acid reductoisomerase; Provisional; Region: PRK05479 663951010412 Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvN; pfam07991 663951010413 Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvC; pfam01450 663951010414 HMMPfam hit to PF07991, IlvN, score 1.3e-111 663951010415 HMMPfam hit to PF01450, IlvC, score 1e-81 663951010416 2-isopropylmalate synthase; Validated; Region: PRK00915 663951010417 2-isopropylmalate synthase (IPMS), N-terminal catalytic TIM barrel domain; Region: DRE_TIM_IPMS; cd07940 663951010418 active site 663951010419 catalytic residues [active] 663951010420 metal binding site [ion binding]; metal-binding site 663951010421 LeuA allosteric (dimerisation) domain; Region: LeuA_dimer; pfam08502 663951010422 HMMPfam hit to PF00682, HMGL-like, score 3.1e-116 663951010423 HMMPfam hit to PF08502, LeuA_dimer, score 1.9e-52 663951010424 3-isopropylmalate dehydrogenase; Provisional; Region: PRK00772 663951010425 tartrate dehydrogenase; Region: TTC; TIGR02089 663951010426 HMMPfam hit to PF00180, Iso_dh, score 5.2e-177 663951010427 PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 663951010428 3-isopropylmalate dehydratase large subunit; Reviewed; Region: PRK00402 663951010429 3-isopropylmalate dehydratase catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate; Region: IPMI; cd01583 663951010430 substrate binding site [chemical binding]; other site 663951010431 ligand binding site [chemical binding]; other site 663951010432 HMMPfam hit to PF00330, Aconitase, score 1.1e-230 663951010433 PS00017 ATP/GTP-binding site motif A (P-loop). 663951010434 PS00450 Aconitase family signature 1. 663951010435 PS01244 Aconitase family signature 2. 663951010436 isopropylmalate isomerase small subunit; Provisional; Region: leuD; PRK01641 663951010437 Aconatase-like swivel domain of 3-isopropylmalate dehydratase and related uncharacterized proteins. 3-isopropylmalate dehydratase catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate...; Region: IPMI_Swivel; cd01577 663951010438 substrate binding site [chemical binding]; other site 663951010439 HMMPfam hit to PF00694, Aconitase_C, score 6.7e-48 663951010440 threonine dehydratase; Validated; Region: PRK08639 663951010441 Threonine dehydratase: The first step in amino acid degradation is the removal of nitrogen. Although the nitrogen atoms of most amino acids are transferred to alpha-ketoglutarate before removal, the alpha-amino group of threonine can be directly...; Region: Thr-dehyd; cd01562 663951010442 tetramer interface [polypeptide binding]; other site 663951010443 pyridoxal 5'-phosphate binding site [chemical binding]; other site 663951010444 catalytic residue [active] 663951010445 Second of two tandem C-terminal ACT domains of threonine dehydratase I (ThrD-I; L-threonine hydrolyase); Region: ACT_ThrD-I_2; cd04907 663951010446 putative Ile/Val binding site [chemical binding]; other site 663951010447 HMMPfam hit to PF00291, PALP, score 2.2e-88 663951010448 PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 663951010449 HMMPfam hit to PF00585, Thr_dehydrat_C, score 1e-25 663951010450 hypothetical protein; Provisional; Region: PRK04351 663951010451 Zn-dependent metalloprotease, SprT family [General function prediction only]; Region: SprT; COG3091 663951010452 HMMPfam hit to PF03926, DUF335, score 2e-41 663951010453 PS00190 Cytochrome c family heme-binding site signature. 663951010454 Transcriptional accessory protein [Transcription]; Region: Tex; COG2183 663951010455 Tex-like protein N-terminal domain; Region: Tex_N; pfam09371 663951010456 Likely ribonuclease with RNase H fold; Region: YqgFc; smart00732 663951010457 S1_Tex: The C-terminal S1 domain of a transcription accessory factor called Tex, which has been characterized in Bordetella pertussis and Pseudomonas aeruginosa. The tex gene is essential in Bortella pertusis and is named for its role in toxin expression; Region: S1_Tex; cd05685 663951010458 RNA binding site [nucleotide binding]; other site 663951010459 HMMPfam hit to PF00575, S1, score 5.1e-19 663951010460 RNA polymerase sigma factor SigB; Validated; Region: PRK08583 663951010461 Sigma-70 region 2; Region: Sigma70_r2; pfam04542 663951010462 Sigma-70 region 3; Region: Sigma70_r3; pfam04539 663951010463 Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171 663951010464 DNA binding residues [nucleotide binding] 663951010465 HMMPfam hit to PF04545, Sigma70_r4, score 6.5e-18 663951010466 Predicted helix-turn-helix motif with score 1939.000, SD 5.79 at aa 223-244, sequence LSQKETGERIGLSQMHVSRLQR 663951010467 HMMPfam hit to PF04539, Sigma70_r3, score 1.7e-22 663951010468 HMMPfam hit to PF04542, Sigma70_r2, score 2e-19 663951010469 PS00715 Sigma-70 factors family signature 1. 663951010470 Anti-sigma regulatory factor (Ser/Thr protein kinase) [Signal transduction mechanisms]; Region: RsbW; COG2172 663951010471 Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075 663951010472 ATP binding site [chemical binding]; other site 663951010473 Mg2+ binding site [ion binding]; other site 663951010474 G-X-G motif; other site 663951010475 HMMPfam hit to PF02518, HATPase_c, score 5.1e-08 663951010476 Sulphate Transporter and Anti-Sigma factor antagonist) domain of anti-anti-sigma factors, key regulators of anti-sigma factors by phosphorylation; Region: STAS_anti-anti-sigma_factors; cd07043 663951010477 anti sigma factor interaction site; other site 663951010478 regulatory phosphorylation site [posttranslational modification]; other site 663951010479 HMMPfam hit to PF01740, STAS, score 3.9e-18 663951010480 Serine phosphatase RsbU, regulator of sigma subunit [Signal transduction mechanisms / Transcription]; Region: RsbU; COG2208 663951010481 Phosphoserine phosphatase RsbU, N-terminal domain; Region: RsbU_N; pfam08673 663951010482 Stage II sporulation protein E (SpoIIE); Region: SpoIIE; pfam07228 663951010483 HMMPfam hit to PF07228, SpoIIE, score 5e-64 663951010484 HMMPfam hit to PF08673, RsbU_N, score 3.9e-43 663951010485 PemK-like protein; Region: PemK; pfam02452 663951010486 HMMPfam hit to PF02452, PemK, score 2.8e-57 663951010487 Alanine racemase [Cell envelope biogenesis, outer membrane]; Region: Alr; COG0787 663951010488 Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Alanine Racemase; Region: PLPDE_III_AR; cd00430 663951010489 active site 663951010490 pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site 663951010491 dimer interface [polypeptide binding]; other site 663951010492 substrate binding site [chemical binding]; other site 663951010493 catalytic residues [active] 663951010494 HMMPfam hit to PF00842, Ala_racemase_C, score 1e-69 663951010495 HMMPfam hit to PF01168, Ala_racemase_N, score 3.5e-98 663951010496 PS00225 Crystallins beta and gamma 'Greek key' motif signature. 663951010497 4'-phosphopantetheinyl transferase; Provisional; Region: acpS; PRK00070 663951010498 HMMPfam hit to PF01648, ACPS, score 6.8e-25 663951010499 Uncharacterized conserved protein [Function unknown]; Region: COG3402 663951010500 HMMPfam hit to PF03703, DUF304, score 3e-22 663951010501 2 probable transmembrane helices predicted for SATW20_22120 by TMHMM2.0 at aa 13-35 and 45-67 663951010502 Predicted membrane protein [Function unknown]; Region: COG3428 663951010503 Bacterial PH domain; Region: DUF304; pfam03703 663951010504 Bacterial PH domain; Region: DUF304; pfam03703 663951010505 6 probable transmembrane helices predicted for SATW20_22130 by TMHMM2.0 at aa 13-35, 45-67, 210-232,252-274, 389-411 and 415-437 663951010506 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 663951010507 HMMPfam hit to PF03703, DUF304, score 1.8e-22 663951010508 HMMPfam hit to PF03703, DUF304, score 2.5e-22 663951010509 Bacterial PH domain; Region: DUF304; cl01348 663951010510 2 probable transmembrane helices predicted for SATW20_22140 by TMHMM2.0 at aa 16-38 and 48-70 663951010511 potassium-transporting ATPase subunit C; Provisional; Region: PRK13998 663951010512 HMMPfam hit to PF02669, KdpC, score 1.2e-49 663951010513 1 probable transmembrane helix predicted for SATW20_22150 by TMHMM2.0 at aa 7-29 663951010514 High-affinity K+ transport system, ATPase chain B [Inorganic ion transport and metabolism]; Region: KdpB; COG2216 663951010515 E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122 663951010516 Soluble P-type ATPase [General function prediction only]; Region: COG4087 663951010517 7 probable transmembrane helices predicted for SATW20_22160 by TMHMM2.0 at aa 33-55, 59-81, 217-239,249-271, 569-591, 611-630 and 650-672 663951010518 HMMPfam hit to PF00702, Hydrolase, score 1.2e-29 663951010519 PS00154 E1-E2 ATPases phosphorylation site. 663951010520 HMMPfam hit to PF00122, E1-E2_ATPase, score 6.9e-54 663951010521 K+-transporting ATPase, A chain [Inorganic ion transport and metabolism]; Region: KdpA; COG2060 663951010522 HMMPfam hit to PF03814, KdpA, score 0 663951010523 12 probable transmembrane helices predicted for SATW20_22170 by TMHMM2.0 at aa 4-26, 63-85, 127-149,169-191, 245-267, 280-302, 325-347, 354-372, 376-398,415-437, 484-506 and 526-548 663951010524 Osmosensitive K+ channel histidine kinase [Signal transduction mechanisms]; Region: KdpD; COG2205 663951010525 Osmosensitive K+ channel His kinase sensor domain; Region: KdpD; pfam02702 663951010526 USP domain is located between the N-terminal sensor domain and C-terminal catalytic domain of this Osmosensitive K+ channel histidine kinase family. The family of KdpD sensor kinase proteins regulates the kdpFABC operon responsible for potassium...; Region: USP_OKCHK; cd01987 663951010527 Ligand Binding Site [chemical binding]; other site 663951010528 Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082 663951010529 dimer interface [polypeptide binding]; other site 663951010530 phosphorylation site [posttranslational modification] 663951010531 Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075 663951010532 ATP binding site [chemical binding]; other site 663951010533 Mg2+ binding site [ion binding]; other site 663951010534 G-X-G motif; other site 663951010535 HMMPfam hit to PF02702, KdpD, score 4.6e-139 663951010536 4 probable transmembrane helices predicted for SATW20_22180 by TMHMM2.0 at aa 383-405, 412-430, 434-453 and 466-484 663951010537 HMMPfam hit to PF00512, HisKA, score 1.6e-11 663951010538 HMMPfam hit to PF02518, HATPase_c, score 2.2e-26 663951010539 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745 663951010540 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 663951010541 active site 663951010542 phosphorylation site [posttranslational modification] 663951010543 intermolecular recognition site; other site 663951010544 dimerization interface [polypeptide binding]; other site 663951010545 Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383 663951010546 DNA binding site [nucleotide binding] 663951010547 HMMPfam hit to PF00072, Response_reg, score 1.2e-35 663951010548 HMMPfam hit to PF00486, Trans_reg_C, score 2.8e-18 663951010549 Superfamily II DNA and RNA helicases [DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis]; Region: SrmB; COG0513 663951010550 DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker B motif; Region: DEADc; cd00268 663951010551 ATP binding site [chemical binding]; other site 663951010552 Mg++ binding site [ion binding]; other site 663951010553 motif III; other site 663951010554 Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079 663951010555 nucleotide binding region [chemical binding]; other site 663951010556 ATP-binding site [chemical binding]; other site 663951010557 HMMPfam hit to PF00271, Helicase_C, score 2.2e-35 663951010558 HMMPfam hit to PF00270, DEAD, score 1.6e-67 663951010559 PS00039 DEAD-box subfamily ATP-dependent helicases signature. 663951010560 PS00017 ATP/GTP-binding site motif A (P-loop). 663951010561 UDP-N-acetylmuramyl pentapeptide synthase [Cell envelope biogenesis, outer membrane]; Region: MurF; COG0770 663951010562 Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225 663951010563 Mur ligase middle domain; Region: Mur_ligase_M; pfam08245 663951010564 Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875 663951010565 HMMPfam hit to PF02875, Mur_ligase_C, score 4.6e-13 663951010566 HMMPfam hit to PF08245, Mur_ligase_M, score 5.9e-53 663951010567 HMMPfam hit to PF01225, Mur_ligase, score 6.9e-20 663951010568 D-alanyl-alanine synthetase A; Reviewed; Region: ddl; PRK01966 663951010569 D-ala D-ala ligase N-terminus; Region: Dala_Dala_lig_N; pfam01820 663951010570 D-ala D-ala ligase C-terminus; Region: Dala_Dala_lig_C; pfam07478 663951010571 HMMPfam hit to PF07478, Dala_Dala_lig_C, score 8.9e-105 663951010572 HMMPfam hit to PF01820, Dala_Dala_lig_N, score 2.1e-50 663951010573 PS00843 D-alanine--D-alanine ligase signature 1. 663951010574 rod shape-determining protein RodA; Region: rodA_shape; TIGR02210 663951010575 HMMPfam hit to PF01098, FTSW_RODA_SPOVE, score 1.4e-105 663951010576 10 probable transmembrane helices predicted for SATW20_22230 by TMHMM2.0 at aa 19-41, 51-70, 77-96,111-133, 153-172, 176-195, 202-224, 296-318, 330-352 and 362-384 663951010577 Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cl00207 663951010578 Staphylococcus aureus copper-sensitive operon repressor (CsoR), and related domains; this family was previously known as part of DUF156; Region: SaCsoR-like_DUF156; cd10152 663951010579 putative homodimer interface [polypeptide binding]; other site 663951010580 putative homotetramer interface [polypeptide binding]; other site 663951010581 allosteric switch controlling residues; other site 663951010582 putative metal binding site [ion binding]; other site 663951010583 putative homodimer-homodimer interface [polypeptide binding]; other site 663951010584 HMMPfam hit to PF02583, DUF156, score 6.6e-39 663951010585 cardiolipin synthase; Region: bac_cardiolipin; TIGR04265 663951010586 Catalytic domain, repeat 1, of bacterial cardiolipin synthase and similar proteins; Region: PLDc_CLS_1; cd09110 663951010587 putative active site [active] 663951010588 catalytic site [active] 663951010589 catalytic domain repeat 2 of bacterial cardiolipin synthase and similar proteins; Region: PLDc_CLS_2; cd09112 663951010590 putative active site [active] 663951010591 catalytic site [active] 663951010592 2 probable transmembrane helices predicted for SATW20_22270 by TMHMM2.0 at aa 13-35 and 45-67 663951010593 HMMPfam hit to PF00614, PLDc, score 6.1e-09 663951010594 PS00017 ATP/GTP-binding site motif A (P-loop). 663951010595 PS00136 Serine proteases, subtilase family, aspartic acid active site. 663951010596 HMMPfam hit to PF00614, PLDc, score 8.7e-09 663951010597 Predicted HD superfamily hydrolase [General function prediction only]; Region: COG1418 663951010598 Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077 663951010599 Zn2+ binding site [ion binding]; other site 663951010600 Mg2+ binding site [ion binding]; other site 663951010601 HMMPfam hit to PF01966, HD, score 1.7e-06 663951010602 60Kd inner membrane protein; Region: 60KD_IMP; cl00489 663951010603 HMMPfam hit to PF02096, 60KD_IMP, score 4.3e-47 663951010604 6 probable transmembrane helices predicted for SATW20_22290 by TMHMM2.0 at aa 5-22, 57-79, 131-153,173-195, 207-224 and 229-251 663951010605 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 663951010606 Thiamine monophosphate synthase (TMP synthase)/TenI. TMP synthase catalyzes an important step in the thiamine biosynthesis pathway, the substitution of the pyrophosphate of 2-methyl-4-amino-5- hydroxymethylpyrimidine pyrophosphate by 4-methyl-5-; Region: TMP_TenI; cd00564 663951010607 thiamine phosphate binding site [chemical binding]; other site 663951010608 active site 663951010609 pyrophosphate binding site [ion binding]; other site 663951010610 HMMPfam hit to PF02581, TMP-TENI, score 2.7e-95 663951010611 4-methyl-5-beta-hydroxyethylthiazole (Thz) kinase catalyzes the phosphorylation of the hydroxylgroup of Thz. A reaction that allows cells to recycle Thz into the thiamine biosynthesis pathway, as an alternative to its synthesis from cysteine, tyrosine...; Region: THZ_kinase; cd01170 663951010612 substrate binding site [chemical binding]; other site 663951010613 multimerization interface [polypeptide binding]; other site 663951010614 ATP binding site [chemical binding]; other site 663951010615 HMMPfam hit to PF02110, HK, score 9.3e-90 663951010616 4-amino-5-hydroxymethyl-2-methyl-pyrimidine phosphate kinase (HMPP-kinase) catalyzes two consecutive phosphorylation steps in the thiamine phosphate biosynthesis pathway, leading to the synthesis of vitamin B1. The first step is the phosphorylation of...; Region: HMPP_kinase; cd01169 663951010617 dimer interface [polypeptide binding]; other site 663951010618 substrate binding site [chemical binding]; other site 663951010619 ATP binding site [chemical binding]; other site 663951010620 HMMPfam hit to PF08543, Phos_pyr_kin, score 3.6e-135 663951010621 thiaminase II; Region: salvage_TenA; TIGR04306 663951010622 HMMPfam hit to PF03070, TENA_THI-4, score 4.8e-40 663951010623 Transglycosylase-like domain; Region: Transglycosylas; pfam06737 663951010624 HMMPfam hit to PF06737, Transglycosylas, score 4.2e-34 663951010625 Single-stranded DNA-binding protein [DNA replication, recombination, and repair]; Region: Ssb; COG0629 663951010626 SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496 663951010627 dimer interface [polypeptide binding]; other site 663951010628 ssDNA binding site [nucleotide binding]; other site 663951010629 tetramer (dimer of dimers) interface [polypeptide binding]; other site 663951010630 HMMPfam hit to PF00436, SSB, score 2.9e-30 663951010631 PS00735 Single-strand binding protein family signature 1. 663951010632 YwpF-like protein; Region: YwpF; pfam14183 663951010633 FabZ is a 17kD beta-hydroxyacyl-acyl carrier protein (ACP) dehydratase that primarily catalyzes the dehydration of beta-hydroxyacyl-ACP to trans-2-acyl-ACP, the third step in the elongation phase of the bacterial/ plastid, type II, fatty-acid...; Region: FabZ; cd01288 663951010634 HMMPfam hit to PF07977, FabA, score 1e-67 663951010635 UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Region: murA; TIGR01072 663951010636 UDP-N-acetylglucosamine enolpyruvyl transferase catalyzes enolpyruvyl transfer as part of the first step in the biosynthesis of peptidoglycan, a component of the bacterial cell wall. The reaction is phosphoenolpyruvate + UDP-N-acetyl-D-glucosamine =...; Region: UdpNAET; cd01555 663951010637 hinge; other site 663951010638 active site 663951010639 HMMPfam hit to PF00275, EPSP_synthase, score 3.4e-145 663951010640 PS00017 ATP/GTP-binding site motif A (P-loop). 663951010641 PS00017 ATP/GTP-binding site motif A (P-loop). 663951010642 Predicted membrane protein [Function unknown]; Region: COG4836 663951010643 HMMPfam hit to PF06612, DUF1146, score 2.8e-55 663951010644 2 probable transmembrane helices predicted for SATW20_22390 by TMHMM2.0 at aa 7-26 and 41-63 663951010645 F0F1 ATP synthase subunit epsilon; Provisional; Region: atpC; PRK14735 663951010646 mitochondrial ATP synthase delta subunit; Region: F1-ATPase_delta; cd12152 663951010647 gamma subunit interface [polypeptide binding]; other site 663951010648 epsilon subunit interface [polypeptide binding]; other site 663951010649 LBP interface [polypeptide binding]; other site 663951010650 HMMPfam hit to PF00401, ATP-synt_DE, score 8e-09 663951010651 HMMPfam hit to PF02823, ATP-synt_DE_N, score 1.6e-29 663951010652 F0F1 ATP synthase subunit beta; Validated; Region: PRK09280 663951010653 ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874 663951010654 F1 ATP synthase beta subunit, nucleotide-binding domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a...; Region: F1-ATPase_beta; cd01133 663951010655 alpha subunit interaction interface [polypeptide binding]; other site 663951010656 Walker A motif; other site 663951010657 ATP binding site [chemical binding]; other site 663951010658 Walker B motif; other site 663951010659 inhibitor binding site; inhibition site 663951010660 ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306 663951010661 HMMPfam hit to PF00306, ATP-synt_ab_C, score 2.2e-53 663951010662 HMMPfam hit to PF00006, ATP-synt_ab, score 9.5e-102 663951010663 PS00152 ATP synthase alpha and beta subunits signature. 663951010664 PS00017 ATP/GTP-binding site motif A (P-loop). 663951010665 HMMPfam hit to PF02874, ATP-synt_ab_N, score 2.7e-25 663951010666 mitochondrial ATP synthase gamma subunit; Region: F1-ATPase_gamma; cd12151 663951010667 core domain interface [polypeptide binding]; other site 663951010668 delta subunit interface [polypeptide binding]; other site 663951010669 epsilon subunit interface [polypeptide binding]; other site 663951010670 HMMPfam hit to PF00231, ATP-synt, score 5.2e-121 663951010671 F0F1 ATP synthase subunit alpha; Validated; Region: PRK09281 663951010672 ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874 663951010673 F1 ATP synthase alpha, central domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a proton gradient to...; Region: F1_ATPase_alpha; cd01132 663951010674 beta subunit interaction interface [polypeptide binding]; other site 663951010675 Walker A motif; other site 663951010676 ATP binding site [chemical binding]; other site 663951010677 Walker B motif; other site 663951010678 ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306 663951010679 HMMPfam hit to PF00306, ATP-synt_ab_C, score 3e-34 663951010680 HMMPfam hit to PF00006, ATP-synt_ab, score 1.6e-120 663951010681 PS00152 ATP synthase alpha and beta subunits signature. 663951010682 PS00017 ATP/GTP-binding site motif A (P-loop). 663951010683 HMMPfam hit to PF02874, ATP-synt_ab_N, score 1.4e-21 663951010684 F0F1 ATP synthase subunit delta; Validated; Region: PRK05758 663951010685 ATP synthase delta (OSCP) subunit; Region: OSCP; pfam00213 663951010686 HMMPfam hit to PF00213, OSCP, score 6.6e-31 663951010687 PS00389 ATP synthase delta (OSCP) subunit signature. 663951010688 F0F1 ATP synthase subunit B; Provisional; Region: PRK13453 663951010689 F0F1-type ATP synthase, subunit b [Energy production and conversion]; Region: AtpF; COG0711 663951010690 HMMPfam hit to PF00430, ATP-synt_B, score 2.3e-33 663951010691 1 probable transmembrane helix predicted for SATW20_22450 by TMHMM2.0 at aa 7-29 663951010692 F0F1 ATP synthase subunit C; Validated; Region: PRK06876 663951010693 HMMPfam hit to PF00137, ATP-synt_C, score 6.7e-29 663951010694 2 probable transmembrane helices predicted for SATW20_22460 by TMHMM2.0 at aa 4-26 and 47-69 663951010695 PS00605 ATP synthase c subunit signature. 663951010696 F0F1 ATP synthase subunit A; Validated; Region: PRK05815 663951010697 F0F1-type ATP synthase, subunit a [Energy production and conversion]; Region: AtpB; COG0356 663951010698 HMMPfam hit to PF00119, ATP-synt_A, score 6.9e-79 663951010699 5 probable transmembrane helices predicted for SATW20_22470 by TMHMM2.0 at aa 15-37, 81-103, 118-137,171-193 and 208-230 663951010700 PS00449 ATP synthase a subunit signature. 663951010701 4 probable transmembrane helices predicted for SATW20_22480 by TMHMM2.0 at aa 12-29, 34-56, 69-86 and 91-113 663951010702 UDP-N-acetylglucosamine 2-epimerase [Cell envelope biogenesis, outer membrane]; Region: WecB; COG0381 663951010703 Bacterial members of the UDP-N-Acetylglucosamine (GlcNAc) 2-Epimerase family are known to catalyze the reversible interconversion of UDP-GlcNAc and UDP-N-acetylmannosamine (UDP-ManNAc). The enzyme serves to produce an activated form of ManNAc residues; Region: GT1_UDP-GlcNAc_2-Epimerase; cd03786 663951010704 active site 663951010705 homodimer interface [polypeptide binding]; other site 663951010706 HMMPfam hit to PF02350, Epimerase_2, score 1.4e-176 663951010707 Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223 663951010708 active site 663951010709 HMMPfam hit to PF00156, Pribosyltran, score 3.5e-12 663951010710 serine hydroxymethyltransferase; Reviewed; Region: glyA; PRK00011 663951010711 Serine-glycine hydroxymethyltransferase (SHMT). This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). SHMT carries out interconversion of serine and glycine; it catalyzes the transfer of hydroxymethyl...; Region: SHMT; cd00378 663951010712 dimer interface [polypeptide binding]; other site 663951010713 active site 663951010714 glycine-pyridoxal phosphate binding site [chemical binding]; other site 663951010715 folate binding site [chemical binding]; other site 663951010716 HMMPfam hit to PF00464, SHMT, score 6.8e-265 663951010717 PS00096 Serine hydroxymethyltransferase pyridoxal-phosphate attachment site. 663951010718 hypothetical protein; Provisional; Region: PRK13690 663951010719 HMMPfam hit to PF04260, DUF436, score 2.9e-130 663951010720 Protein-tyrosine-phosphatase [Signal transduction mechanisms]; Region: Wzb; COG0394 663951010721 Low molecular weight phosphatase family; Region: LMWPc; cd00115 663951010722 active site 663951010723 HMMPfam hit to PF01451, LMWPc, score 3.3e-21 663951010724 Putative translation factor (SUA5) [Translation, ribosomal structure and biogenesis]; Region: SUA5; COG0009 663951010725 Putative GTP-binding controlling metal-binding; Region: SUA5; pfam03481 663951010726 HMMPfam hit to PF03481, SUA5, score 4.3e-60 663951010727 HMMPfam hit to PF01300, Sua5_yciO_yrdC, score 5.3e-58 663951010728 N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase; Provisional; Region: PRK09328 663951010729 S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440 663951010730 S-adenosylmethionine binding site [chemical binding]; other site 663951010731 PS00092 N-6 Adenine-specific DNA methylases signature. 663951010732 HMMPfam hit to PF08241, Methyltransf_11, score 1.2e-06 663951010733 peptide chain release factor 1; Validated; Region: prfA; PRK00591 663951010734 This domain is found in peptide chain release factors; Region: PCRF; smart00937 663951010735 RF-1 domain; Region: RF-1; pfam00472 663951010736 HMMPfam hit to PF00472, RF-1, score 8.4e-71 663951010737 PS00745 Prokaryotic-type class I peptide chain release factors signature. 663951010738 HMMPfam hit to PF03462, PCRF, score 2.4e-70 663951010739 thymidine kinase; Provisional; Region: PRK04296 663951010740 PS00014 Endoplasmic reticulum targeting sequence. 663951010741 HMMPfam hit to PF00265, TK, score 1.4e-81 663951010742 PS00603 Thymidine kinase cellular-type signature. 663951010743 PS00017 ATP/GTP-binding site motif A (P-loop). 663951010744 50S ribosomal protein L31 type B; Reviewed; Region: rpmE2; PRK01678 663951010745 HMMPfam hit to PF01197, Ribosomal_L31, score 3e-20 663951010746 PS01143 Ribosomal protein L31 signature. 663951010747 transcription termination factor Rho; Provisional; Region: rho; PRK09376 663951010748 Rho termination factor, N-terminal domain; Region: Rho_N; pfam07498 663951010749 Rho_CSD: Rho protein cold-shock domain (CSD). Rho protein is a transcription termination factor in most bacteria. In bacteria, there are two distinct mechanisms for mRNA transcription termination. In intrinsic termination, RNA polymerase and nascent mRNA...; Region: Rho_CSD; cd04459 663951010750 RNA binding site [nucleotide binding]; other site 663951010751 Transcription termination factor rho is a bacterial ATP-dependent RNA/DNA helicase. It is a homohexamer. Each monomer consists of an N-terminal domain of the OB fold, which is responsible for binding to cysteine rich nucleotides. This alignment is of the...; Region: rho_factor; cd01128 663951010752 multimer interface [polypeptide binding]; other site 663951010753 Walker A motif; other site 663951010754 ATP binding site [chemical binding]; other site 663951010755 Walker B motif; other site 663951010756 HMMPfam hit to PF00006, ATP-synt_ab, score 1.3e-72 663951010757 PS00017 ATP/GTP-binding site motif A (P-loop). 663951010758 HMMPfam hit to PF07497, Rho_RNA_bind, score 3.3e-38 663951010759 HMMPfam hit to PF07498, Rho_N, score 1.5e-13 663951010760 Rhodococcus ruber 6-oxolauric acid dehydrogenase-like; Region: ALDH_CddD_SSP0762; cd07138 663951010761 Aldehyde dehydrogenase family; Region: Aldedh; pfam00171 663951010762 NAD binding site [chemical binding]; other site 663951010763 catalytic residues [active] 663951010764 HMMPfam hit to PF00171, Aldedh, score 4.7e-224 663951010765 PS00070 Aldehyde dehydrogenases cysteine active site. 663951010766 PS00687 Aldehyde dehydrogenases glutamic acid active site. 663951010767 Predicted transcriptional regulators [Transcription]; Region: COG1733 663951010768 HxlR-like helix-turn-helix; Region: HxlR; pfam01638 663951010769 HMMPfam hit to PF01638, DUF24, score 7.5e-12 663951010770 UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Region: murA; TIGR01072 663951010771 UDP-N-acetylglucosamine enolpyruvyl transferase catalyzes enolpyruvyl transfer as part of the first step in the biosynthesis of peptidoglycan, a component of the bacterial cell wall. The reaction is phosphoenolpyruvate + UDP-N-acetyl-D-glucosamine =...; Region: UdpNAET; cd01555 663951010772 hinge; other site 663951010773 active site 663951010774 HMMPfam hit to PF00275, EPSP_synthase, score 1.6e-98 663951010775 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 663951010776 fructose-bisphosphate aldolase; Provisional; Region: PRK09197 663951010777 Tagatose-1,6-bisphosphate (TBP) aldolase and related Type B Class II aldolases. TBP aldolase is a tetrameric class II aldolase that catalyzes the reversible condensation of dihydroxyacetone phosphate with glyceraldehyde 3-phsophate to produce tagatose 1; Region: TBP_aldolase_IIB; cd00947 663951010778 intersubunit interface [polypeptide binding]; other site 663951010779 active site 663951010780 zinc binding site [ion binding]; other site 663951010781 Na+ binding site [ion binding]; other site 663951010782 HMMPfam hit to PF01116, F_bP_aldolase, score 1.6e-157 663951010783 PS00806 Fructose-bisphosphate aldolase class-II signature 2. 663951010784 Protein of unknown function (DUF2529); Region: DUF2529; pfam10740 663951010785 CTP synthetase; Validated; Region: pyrG; PRK05380 663951010786 CTP synthetase (CTPs) is a two-domain protein, which consists of an N-terminal synthetase domain and C-terminal glutaminase domain. The enzymes hydrolyze the amide bond of glutamine to ammonia and glutamate at the glutaminase domains and transfer nascent...; Region: CTGs; cd03113 663951010787 Catalytic site [active] 663951010788 active site 663951010789 UTP binding site [chemical binding]; other site 663951010790 Type 1 glutamine amidotransferase (GATase1) domain found in Cytidine Triphosphate Synthetase; Region: GATase1_CTP_Synthase; cd01746 663951010791 active site 663951010792 putative oxyanion hole; other site 663951010793 catalytic triad [active] 663951010794 HMMPfam hit to PF00117, GATase, score 4.2e-72 663951010795 PS00442 Glutamine amidotransferases class-I active site. 663951010796 HMMPfam hit to PF06418, CTP_synth_N, score 2.8e-208 663951010797 DNA-directed RNA polymerase delta subunit; Region: RNA_pol_delta; pfam05066 663951010798 HMMPfam hit to PF05066, RNA_pol_delta, score 2.5e-16 663951010799 Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis]; Region: RimL; COG1670 663951010800 N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301 663951010801 Coenzyme A binding pocket [chemical binding]; other site 663951010802 N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182 663951010803 Coenzyme A binding pocket [chemical binding]; other site 663951010804 HMMPfam hit to PF00583, Acetyltransf_1, score 9.4e-13 663951010805 pantothenate kinase; Provisional; Region: PRK13317 663951010806 pantothenate kinase, eukaryotic/staphyloccocal type; Region: panK_eukar; TIGR00555 663951010807 HMMPfam hit to PF03630, Fumble, score 5.1e-124 663951010808 Protein of unknown function (DUF2750); Region: DUF2750; pfam11042 663951010809 ATP-grasp domain; Region: ATP-grasp_4; pfam13535 663951010810 Metal-dependent amidase/aminoacylase/carboxypeptidase [General function prediction only]; Region: AbgB; COG1473 663951010811 M20 Peptidase Aminoacylase 1-like protein 2-like, amidohydrolase subfamily; Region: M20_ACY1L2_like; cd05672 663951010812 metal binding site [ion binding]; metal-binding site 663951010813 HMMPfam hit to PF01546, Peptidase_M20, score 0.00034 663951010814 HMMPfam hit to PF07687, M20_dimer, score 0.00096 663951010815 S-ribosylhomocysteinase; Provisional; Region: PRK02260 663951010816 HMMPfam hit to PF02664, LuxS, score 3.7e-84 663951010817 Predicted membrane protein [Function unknown]; Region: COG4270 663951010818 3 probable transmembrane helices predicted for SATW20_22730 by TMHMM2.0 at aa 4-21, 40-57 and 67-84 663951010819 pyrimidine-nucleoside phosphorylase; Reviewed; Region: PRK06078 663951010820 Glycosyl transferase family, helical bundle domain; Region: Glycos_trans_3N; pfam02885 663951010821 Glycosyl transferase family, a/b domain; Region: Glycos_transf_3; pfam00591 663951010822 Pyrimidine nucleoside phosphorylase C-terminal domain; Region: PYNP_C; pfam07831 663951010823 HMMPfam hit to PF07831, PYNP_C, score 2e-36 663951010824 HMMPfam hit to PF00591, Glycos_transf_3, score 8.5e-58 663951010825 PS00647 Thymidine and pyrimidine-nucleoside phosphorylases signature. 663951010826 HMMPfam hit to PF02885, Glycos_trans_3N, score 2.3e-23 663951010827 2-deoxyribose-5-phosphate aldolase (DERA) of the DeoC family; Region: DeoC; cd00959 663951010828 intersubunit interface [polypeptide binding]; other site 663951010829 active site 663951010830 catalytic residue [active] 663951010831 HMMPfam hit to PF01791, DeoC, score 6.8e-85 663951010832 Uridine phosphorylase [Nucleotide transport and metabolism]; Region: Udp; COG2820 663951010833 purine nucleoside phosphorylase; Reviewed; Region: deoD; PRK05819 663951010834 HMMPfam hit to PF01048, PNP_UDP_1, score 3.1e-96 663951010835 PS01232 Purine and other phosphorylases family 1 signature. 663951010836 DNA-binding ferritin-like protein (oxidative damage protectant) [Inorganic ion transport and metabolism]; Region: Dps; COG0783 663951010837 DPS protein, ferritin-like diiron-binding domain; Region: DPS; cd01043 663951010838 dimerization interface [polypeptide binding]; other site 663951010839 DPS ferroxidase diiron center [ion binding]; other site 663951010840 ion pore; other site 663951010841 HMMPfam hit to PF00210, Ferritin, score 2.6e-25 663951010842 PS00818 Dps protein family signature 1. 663951010843 Predicted thiol-disulfide oxidoreductase [General function prediction only]; Region: COG3011 663951010844 HMMPfam hit to PF04134, DUF393, score 2.7e-07 663951010845 EVE domain; Region: EVE; cl00728 663951010846 HMMPfam hit to PF01878, DUF55, score 0.0051 663951010847 3 probable transmembrane helices predicted for SATW20_22800 by TMHMM2.0 at aa 5-24, 29-47 and 52-74 663951010848 PS00443 Glutamine amidotransferases class-II active site. 663951010849 Phosphomannose isomerase [Carbohydrate transport and metabolism]; Region: ManA; COG1482 663951010850 mannose-6-phosphate isomerase, class I; Region: manA; TIGR00218 663951010851 HMMPfam hit to PF01238, PMI_typeI, score 5e-17 663951010852 atypical (a) SDRs, subgroup 5; Region: SDR_a5; cd05243 663951010853 NADH(P)-binding; Region: NAD_binding_10; pfam13460 663951010854 NAD(P) binding site [chemical binding]; other site 663951010855 putative active site [active] 663951010856 HMMPfam hit to PF01370, Epimerase, score 0.00073 663951010857 Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090 663951010858 dimerization interface [polypeptide binding]; other site 663951010859 putative DNA binding site [nucleotide binding]; other site 663951010860 putative Zn2+ binding site [ion binding]; other site 663951010861 HMMPfam hit to PF01022, HTH_5, score 2.1e-10 663951010862 Predicted helix-turn-helix motif with score 1380.000, SD 3.89 at aa 40-61, sequence ASVGHISHQLNLSQSNVSHQLK 663951010863 Co/Zn/Cd efflux system component [Inorganic ion transport and metabolism]; Region: CzcD; COG1230 663951010864 Predicted Co/Zn/Cd cation transporters [Inorganic ion transport and metabolism]; Region: MMT1; COG0053 663951010865 6 probable transmembrane helices predicted for SATW20_22840 by TMHMM2.0 at aa 22-44, 54-73, 90-112,127-145, 158-180 and 185-207 663951010866 HMMPfam hit to PF01545, Cation_efflux, score 1.7e-115 663951010867 6 probable transmembrane helices predicted for SATW20_22850 by TMHMM2.0 at aa 20-42, 66-88, 118-140,173-195, 230-252 and 267-289 663951010868 Probable gene remnant 663951010869 HMMPfam hit to PF00239, Resolvase, score 2.4e-13 663951010870 SAP domain; Region: SAP; pfam02037 663951010871 HMMPfam hit to PF02037, SAP, score 1.4e-05 663951010872 Predicted hydrolases of the HAD superfamily [General function prediction only]; Region: Cof; COG0561 663951010873 Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427 663951010874 active site 663951010875 motif I; other site 663951010876 motif II; other site 663951010877 Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427 663951010878 HMMPfam hit to PF08282, Hydrolase_3, score 1.7e-56 663951010879 ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components [Inorganic ion transport and metabolism / Coenzyme metabolism]; Region: FepC; COG1120 663951010880 ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201 663951010881 Walker A/P-loop; other site 663951010882 ATP binding site [chemical binding]; other site 663951010883 Q-loop/lid; other site 663951010884 ABC transporter signature motif; other site 663951010885 Walker B; other site 663951010886 D-loop; other site 663951010887 H-loop/switch region; other site 663951010888 HMMPfam hit to PF00005, ABC_tran, score 2.7e-41 663951010889 PS00017 ATP/GTP-binding site motif A (P-loop). 663951010890 PS00017 ATP/GTP-binding site motif A (P-loop). 663951010891 glucosamine--fructose-6-phosphate aminotransferase; Reviewed; Region: PRK00331 663951010892 Glutamine amidotransferases class-II (Gn-AT)_GFAT-type. This domain is found at the N-terminus of glucosamine-6P synthase (GlmS, or GFAT in humans). The glutaminase domain catalyzes amide nitrogen transfer from glutamine to the appropriate substrate. In...; Region: GFAT; cd00714 663951010893 glutaminase active site [active] 663951010894 SIS (Sugar ISomerase) domain repeat 1 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_1; cd05008 663951010895 dimer interface [polypeptide binding]; other site 663951010896 active site 663951010897 SIS (Sugar ISomerase) domain repeat 2 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_2; cd05009 663951010898 dimer interface [polypeptide binding]; other site 663951010899 active site 663951010900 HMMPfam hit to PF01380, SIS, score 7.8e-16 663951010901 HMMPfam hit to PF01380, SIS, score 2.7e-35 663951010902 HMMPfam hit to PF00310, GATase_2, score 2.7e-43 663951010903 PS00443 Glutamine amidotransferases class-II active site. 663951010904 Phosphotransferase system, mannitol-specific IIBC component [Carbohydrate transport and metabolism]; Region: MtlA; COG2213 663951010905 PTS system, mannitol-specific IIC component; Region: mtlA; TIGR00851 663951010906 PTS_IIB_mannitol: subunit IIB of enzyme II (EII) of the mannitol-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is a mannitol-specific permease with two cytoplasmic domains (IIA and IIB) and a transmembrane...; Region: PTS_IIB_mannitol; cd05567 663951010907 active site 663951010908 P-loop; other site 663951010909 phosphorylation site [posttranslational modification] 663951010910 9 probable transmembrane helices predicted for SATW20_22910 by TMHMM2.0 at aa 21-43, 53-72, 93-115,135-157, 164-186, 219-241, 248-270, 275-297 and 318-340 663951010911 HMMPfam hit to PF02378, PTS_EIIC, score 4.8e-19 663951010912 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 663951010913 HMMPfam hit to PF02302, PTS_IIB, score 6.4e-20 663951010914 Transcriptional antiterminator [Transcription]; Region: BglG; COG3711 663951010915 HTH domain; Region: HTH_11; pfam08279 663951010916 Mga helix-turn-helix domain; Region: Mga; pfam05043 663951010917 PRD domain; Region: PRD; pfam00874 663951010918 PRD domain; Region: PRD; pfam00874 663951010919 PTS_IIB_bgl_like: the PTS (phosphotransferase system) IIB domain of a family of sensory systems composed of a membrane-bound sugar-sensor (similar to BglF) and a transcription antiterminator (similar to BglG) which regulate expression of genes involved...; Region: PTS_IIB_bgl_like; cd05568 663951010920 active site 663951010921 P-loop; other site 663951010922 phosphorylation site [posttranslational modification] 663951010923 PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cl00163 663951010924 active site 663951010925 phosphorylation site [posttranslational modification] 663951010926 HMMPfam hit to PF08279, HTH_11, score 3.5e-07 663951010927 Predicted helix-turn-helix motif with score 1504.000, SD 4.31 at aa 22-43, sequence ITIHDIAQQLAVSSRTIHRELK 663951010928 HMMPfam hit to PF08279, HTH_11, score 0.0011 663951010929 Predicted helix-turn-helix motif with score 1415.000, SD 4.01 at aa 108-129, sequence VKQYSLAQEIGVSVQTLAKMLD 663951010930 HMMPfam hit to PF00874, PRD, score 1.3e-15 663951010931 HMMPfam hit to PF00874, PRD, score 7.4e-16 663951010932 HMMPfam hit to PF02302, PTS_IIB, score 3.5e-05 663951010933 PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211 663951010934 active site 663951010935 phosphorylation site [posttranslational modification] 663951010936 HMMPfam hit to PF00359, PTS_EIIA_2, score 3.6e-65 663951010937 PS00372 PTS EIIA domains phosphorylation site signature 2. 663951010938 mannitol-1-phosphate 5-dehydrogenase; Provisional; Region: PRK02318 663951010939 Mannitol dehydrogenase Rossmann domain; Region: Mannitol_dh; pfam01232 663951010940 Mannitol dehydrogenase C-terminal domain; Region: Mannitol_dh_C; pfam08125 663951010941 HMMPfam hit to PF01232, Mannitol_dh, score 3e-34 663951010942 HMMPfam hit to PF08125, Mannitol_dh_C, score 3.5e-53 663951010943 PS00974 Mannitol dehydrogenases signature. 663951010944 YSIRK type signal peptide; Region: YSIRK_signal; pfam04650 663951010945 SasC/Mrp/FmtB intercellular aggregation domain; Region: SasC_Mrp_aggreg; TIGR04263 663951010946 Domain of Unknown Function (DUF1542); Region: DUF1542; pfam07564 663951010947 Domain of Unknown Function (DUF1542); Region: DUF1542; pfam07564 663951010948 Domain of Unknown Function (DUF1542); Region: DUF1542; pfam07564 663951010949 Domain of Unknown Function (DUF1542); Region: DUF1542; pfam07564 663951010950 Domain of Unknown Function (DUF1542); Region: DUF1542; pfam07564 663951010951 Domain of Unknown Function (DUF1542); Region: DUF1542; pfam07564 663951010952 HMMPfam hit to PF07564, DUF1542, score 1.3e-14 663951010953 HMMPfam hit to PF07564, DUF1542, score 5.7e-15 663951010954 HMMPfam hit to PF07564, DUF1542, score 2.5e-16 663951010955 HMMPfam hit to PF07564, DUF1542, score 2.9e-15 663951010956 HMMPfam hit to PF07564, DUF1542, score 3e-15 663951010957 HMMPfam hit to PF07564, DUF1542, score 1.5e-17 663951010958 HMMPfam hit to PF07564, DUF1542, score 5.9e-19 663951010959 HMMPfam hit to PF07564, DUF1542, score 2.9e-13 663951010960 HMMPfam hit to PF07564, DUF1542, score 2.1e-17 663951010961 HMMPfam hit to PF07564, DUF1542, score 5.3e-14 663951010962 HMMPfam hit to PF07564, DUF1542, score 7.5e-16 663951010963 HMMPfam hit to PF07564, DUF1542, score 2e-17 663951010964 HMMPfam hit to PF07564, DUF1542, score 1.8e-14 663951010965 HMMPfam hit to PF07564, DUF1542, score 5.8e-16 663951010966 HMMPfam hit to PF07564, DUF1542, score 7.6e-12 663951010967 HMMPfam hit to PF07564, DUF1542, score 2.2e-16 663951010968 HMMPfam hit to PF07564, DUF1542, score 1.6e-12 663951010969 HMMPfam hit to PF07564, DUF1542, score 4e-15 663951010970 HMMPfam hit to PF07554, FIVAR, score 2.5e-06 663951010971 HMMPfam hit to PF04650, YSIRK_signal, score 4.8e-09 663951010972 phosphoglucosamine mutase; Provisional; Region: glmM; PRK14316 663951010973 GlmM is a bacterial phosphoglucosamine mutase (PNGM) that belongs to the alpha-D-phosphohexomutase superfamily. It is required for the interconversion of glucosamine-6-phosphate and glucosamine-1-phosphate in the biosynthetic pathway of...; Region: GlmM; cd05802 663951010974 active site 663951010975 substrate binding site [chemical binding]; other site 663951010976 metal binding site [ion binding]; metal-binding site 663951010977 HMMPfam hit to PF00408, PGM_PMM_IV, score 1.1e-08 663951010978 HMMPfam hit to PF02880, PGM_PMM_III, score 1.1e-26 663951010979 HMMPfam hit to PF02879, PGM_PMM_II, score 4.3e-24 663951010980 HMMPfam hit to PF02878, PGM_PMM_I, score 1.1e-59 663951010981 PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 663951010982 Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4856 663951010983 YbbR-like protein; Region: YbbR; pfam07949 663951010984 HMMPfam hit to PF07949, YbbR, score 2.8e-07 663951010985 HMMPfam hit to PF07949, YbbR, score 1.8e-13 663951010986 HMMPfam hit to PF07949, YbbR, score 1.2e-13 663951010987 1 probable transmembrane helix predicted for SATW20_22970 by TMHMM2.0 at aa 10-32 663951010988 TIGR00159 family protein; Region: TIGR00159 663951010989 DisA bacterial checkpoint controller nucleotide-binding; Region: DisA_N; pfam02457 663951010990 HMMPfam hit to PF02457, DUF147, score 6.1e-73 663951010991 2 probable transmembrane helices predicted for SATW20_22980 by TMHMM2.0 at aa 15-37 and 44-66 663951010992 Arginase family; Region: Arginase; cd09989 663951010993 active site 663951010994 Mn binding site [ion binding]; other site 663951010995 oligomer interface [polypeptide binding]; other site 663951010996 HMMPfam hit to PF00491, Arginase, score 1.8e-114 663951010997 PS01053 Arginase family signature 3. 663951010998 PS00148 Arginase family signature 2. 663951010999 PS00147 Arginase family signature 1. 663951011000 Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3464 663951011001 Transposase; Region: DDE_Tnp_ISL3; pfam01610 663951011002 Predicted helix-turn-helix motif with score 1283.000, SD 3.56 at aa 124-145, sequence KTEIDTAEDNCISPSTVSRIRT 663951011003 HMMPfam hit to PF01610, Transposase_12, score 1.5e-49 663951011004 ATPases involved in chromosome partitioning [Cell division and chromosome partitioning]; Region: Mrp; COG0489 663951011005 MRP (Multiple Resistance and pH adaptation) is a homologue of the Fer4_NifH superfamily. Like the other members of the superfamily, MRP contains a ATP-binding domain at the N-termini. It is found in bacteria as a membrane-spanning protein and functions...; Region: MRP-like; cd02037 663951011006 Walker A motif; other site 663951011007 PS00017 ATP/GTP-binding site motif A (P-loop). 663951011008 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 663951011009 Major Facilitator Superfamily; Region: MFS_1; pfam07690 663951011010 putative substrate translocation pore; other site 663951011011 14 probable transmembrane helices predicted for SATW20_23020 by TMHMM2.0 at aa 13-35, 50-72, 81-100,110-132, 137-159, 169-191, 204-221, 225-247, 267-289,299-321, 333-352, 362-384, 404-426 and 446-468 663951011012 HMMPfam hit to PF07690, MFS_1, score 3.1e-67 663951011013 4 probable transmembrane helices predicted for SATW20_23030 by TMHMM2.0 at aa 20-42, 63-80, 95-117 and 122-141 663951011014 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 663951011015 Major Facilitator Superfamily; Region: MFS_1; pfam07690 663951011016 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 663951011017 14 probable transmembrane helices predicted for SATW20_23040 by TMHMM2.0 at aa 7-29, 39-61, 68-87, 97-119,131-153, 157-179, 199-214, 218-237, 257-279, 289-311,323-342, 346-363, 384-406 and 416-438 663951011018 HMMPfam hit to PF07690, MFS_1, score 1.5e-61 663951011019 Predicted membrane protein, hemolysin III homolog [General function prediction only]; Region: COG1272 663951011020 channel protein, hemolysin III family; Region: hlyIII; TIGR01065 663951011021 7 probable transmembrane helices predicted for SATW20_23050 by TMHMM2.0 at aa 33-55, 59-81, 93-115,119-141, 154-173, 177-198 and 205-227 663951011022 HMMPfam hit to PF03006, HlyIII, score 7.5e-61 663951011023 UDP-glucose pyrophosphorylase [Carbohydrate transport and metabolism]; Region: COG4284 663951011024 UDPGlcNAc pyrophosphorylase catalayzes the synthesis of UDPGlcNAc; Region: UDPGlcNAc_PPase; cd04193 663951011025 substrate binding site; other site 663951011026 dimerization interface; other site 663951011027 HMMPfam hit to PF01704, UDPGP, score 8.4e-16 663951011028 Predicted membrane-bound metal-dependent hydrolases [General function prediction only]; Region: COG1988 663951011029 4 probable transmembrane helices predicted for SATW20_23070 by TMHMM2.0 at aa 20-42, 62-84, 94-116 and 137-159 663951011030 HMMPfam hit to PF04307, DUF457, score 1.4e-39 663951011031 Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3314 663951011032 Nucleoside recognition; Region: Gate; pfam07670 663951011033 10 probable transmembrane helices predicted for SATW20_23090 by TMHMM2.0 at aa 9-31, 60-82, 95-117,132-154, 216-235, 245-267, 330-352, 372-394, 401-423 and 433-455 663951011034 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 663951011035 HMMPfam hit to PF07670, Gate, score 5.3e-16 663951011036 iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577 663951011037 Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550 663951011038 ABC-ATPase subunit interface; other site 663951011039 dimer interface [polypeptide binding]; other site 663951011040 putative PBP binding regions; other site 663951011041 HMMPfam hit to PF01032, FecCD, score 4.2e-109 663951011042 8 probable transmembrane helices predicted for SATW20_23100 by TMHMM2.0 at aa 28-47, 57-75, 80-102,112-134, 154-176, 204-226, 239-261 and 271-288 663951011043 ABC-type enterobactin transport system, permease component [Inorganic ion transport and metabolism]; Region: FepG; COG4779 663951011044 Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550 663951011045 ABC-ATPase subunit interface; other site 663951011046 dimer interface [polypeptide binding]; other site 663951011047 putative PBP binding regions; other site 663951011048 8 probable transmembrane helices predicted for SATW20_23110 by TMHMM2.0 at aa 21-43, 70-92, 105-124,128-150, 206-228, 248-279, 286-308 and 318-340 663951011049 HMMPfam hit to PF01032, FecCD, score 6.5e-120 663951011050 ABC-type Fe3+-citrate transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: FecB; COG4594 663951011051 Fe3+-siderophore binding domain FhuD. These proteins have been shown to function as initial receptors in ABC transport of Fe3+-siderophores in many eubacterial species. They belong to the TroA-like superfamily of helical backbone metal receptor proteins...; Region: FhuD; cd01146 663951011052 siderophore binding site; other site 663951011053 HMMPfam hit to PF01497, Peripla_BP_2, score 6.9e-55 663951011054 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 663951011055 Predicted amino acid racemase [Amino acid transport and metabolism]; Region: COG3457 663951011056 Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Alanine Racemase-like 1; Region: PLPDE_III_AR_like_1; cd06815 663951011057 dimer interface [polypeptide binding]; other site 663951011058 active site 663951011059 pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site 663951011060 substrate binding site [chemical binding]; other site 663951011061 catalytic residue [active] 663951011062 HMMPfam hit to PF01168, Ala_racemase_N, score 2.5e-40 663951011063 Siderophore synthetase component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: RhbC; COG4264 663951011064 IucA / IucC family; Region: IucA_IucC; pfam04183 663951011065 Ferric iron reductase FhuF-like transporter; Region: FhuF; pfam06276 663951011066 HMMPfam hit to PF04183, IucA_IucC, score 5.1e-171 663951011067 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 663951011068 putative substrate translocation pore; other site 663951011069 9 probable transmembrane helices predicted for SATW20_23150 by TMHMM2.0 at aa 25-47, 85-107, 111-133,161-183, 193-212, 219-240, 244-261, 281-303 and 307-329 663951011070 HMMPfam hit to PF07690, MFS_1, score 8.8e-09 663951011071 HMMPfam hit to PF05977, DUF894, score 5.9e-13 663951011072 Siderophore synthetase component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: RhbC; COG4264 663951011073 IucA / IucC family; Region: IucA_IucC; pfam04183 663951011074 Ferric iron reductase FhuF-like transporter; Region: FhuF; pfam06276 663951011075 HMMPfam hit to PF04183, IucA_IucC, score 5.7e-187 663951011076 Possible pseudogene 663951011077 HMMPfam hit to PF01609, Transposase_11, score 2e-05 663951011078 HMMPfam hit to PF01609, Transposase_11, score 7.1e-11 663951011079 Asp23 family; Region: Asp23; pfam03780 663951011080 HMMPfam hit to PF03780, DUF322, score 2.3e-26 663951011081 Small integral membrane protein [Function unknown]; Region: COG5547 663951011082 2 probable transmembrane helices predicted for SATW20_23210 by TMHMM2.0 at aa 22-41 and 45-64 663951011083 1 probable transmembrane helix predicted for SATW20_23220 by TMHMM2.0 at aa 20-42 663951011084 Choline-glycine betaine transporter [Cell envelope biogenesis, outer membrane]; Region: BetT; COG1292 663951011085 HMMPfam hit to PF02028, BCCT, score 4.6e-218 663951011086 12 probable transmembrane helices predicted for SATW20_23230 by TMHMM2.0 at aa 5-27, 42-64, 85-107,137-159, 188-210, 225-247, 260-282, 313-335, 348-370,394-416, 437-459 and 463-485 663951011087 PS01303 BCCT family of transporters signature. 663951011088 Arginate lyase and other MDR family members; Region: AL_MDR; cd08252 663951011089 zinc-binding alcohol dehydrogenase family protein; Region: adh_fam_1; TIGR02817 663951011090 putative NAD(P) binding site [chemical binding]; other site 663951011091 dimer interface [polypeptide binding]; other site 663951011092 HMMPfam hit to PF00107, ADH_zinc_N, score 3.7e-15 663951011093 HMMPfam hit to PF08240, ADH_N, score 2.5e-14 663951011094 Putative NADP-dependent oxidoreductases [General function prediction only]; Region: COG2130 663951011095 Prostaglandin dehydrogenases; Region: PGDH; cd05288 663951011096 NAD(P) binding site [chemical binding]; other site 663951011097 substrate binding site [chemical binding]; other site 663951011098 dimer interface [polypeptide binding]; other site 663951011099 HMMPfam hit to PF00107, ADH_zinc_N, score 3.7e-24 663951011100 Uncharacterized protein with an alpha/beta hydrolase fold [General function prediction only]; Region: COG4814 663951011101 HMMPfam hit to PF06028, DUF915, score 3.3e-144 663951011102 1 probable transmembrane helix predicted for SATW20_23260 by TMHMM2.0 at aa 4-26 663951011103 6-phospho-beta-galactosidase; Provisional; Region: PRK13511 663951011104 beta-galactosidase; Region: BGL; TIGR03356 663951011105 HMMPfam hit to PF00232, Glyco_hydro_1, score 7.5e-286 663951011106 PS00572 Glycosyl hydrolases family 1 active site. 663951011107 PS00225 Crystallins beta and gamma 'Greek key' motif signature. 663951011108 PS00653 Glycosyl hydrolases family 1 N-terminal signature. 663951011109 phosphotransferase system, lactose specific, IIC component; Region: lac_pts_IIC; TIGR00394 663951011110 Phosphotransferase system, EIIC; Region: PTS_EIIC; pfam02378 663951011111 PTS_IIB: subunit IIB of enzyme II (EII) is the central energy-coupling domain of the phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In the multienzyme PTS complex, EII is a carbohydrate-specific permease consisting of two cytoplasmic...; Region: PTS_IIB; cl10014 663951011112 active site 663951011113 P-loop; other site 663951011114 phosphorylation site [posttranslational modification] 663951011115 HMMPfam hit to PF02302, PTS_IIB, score 8e-33 663951011116 10 probable transmembrane helices predicted for SATW20_23280 by TMHMM2.0 at aa 33-55, 75-93, 106-123,138-160, 183-200, 220-242, 285-307, 335-357, 364-386 and 391-413 663951011117 HMMPfam hit to PF02378, PTS_EIIC, score 1.7e-114 663951011118 PTS_IIA, PTS system, lactose/cellobiose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_lac; cd00215 663951011119 methionine cluster; other site 663951011120 active site 663951011121 phosphorylation site [posttranslational modification] 663951011122 metal binding site [ion binding]; metal-binding site 663951011123 HMMPfam hit to PF02255, PTS_IIA, score 2.7e-60 663951011124 tagatose 1,6-diphosphate aldolase; Reviewed; Region: PRK12399 663951011125 HMMPfam hit to PF01791, DeoC, score 4.4e-113 663951011126 1-phosphofructokinase (FruK), minor 6-phosphofructokinase (pfkB) and related sugar kinases. FruK plays an important role in the predominant pathway for fructose utilisation.This group also contains tagatose-6-phophate kinase, an enzyme of the tagatose...; Region: FruK_PfkB_like; cd01164 663951011127 tagatose-6-phosphate kinase; Region: lacC; TIGR01231 663951011128 putative substrate binding site [chemical binding]; other site 663951011129 putative ATP binding site [chemical binding]; other site 663951011130 HMMPfam hit to PF00294, PfkB, score 9.6e-70 663951011131 PS00584 pfkB family of carbohydrate kinases signature 2. 663951011132 PS00583 pfkB family of carbohydrate kinases signature 1. 663951011133 galactose-6-phosphate isomerase subunit LacB; Reviewed; Region: PRK08622 663951011134 HMMPfam hit to PF02502, LacAB_rpiB, score 7.8e-65 663951011135 galactose-6-phosphate isomerase subunit LacA; Reviewed; Region: PRK08621 663951011136 HMMPfam hit to PF02502, LacAB_rpiB, score 6.6e-55 663951011137 Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349 663951011138 DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220 663951011139 DeoR C terminal sensor domain; Region: DeoRC; pfam00455 663951011140 HMMPfam hit to PF00455, DeoR, score 1.7e-84 663951011141 HMMPfam hit to PF08220, HTH_DeoR, score 9.8e-29 663951011142 PS00894 Bacterial regulatory proteins, deoR family signature. 663951011143 NAD-dependent deacetylase; Provisional; Region: PRK00481 663951011144 SIR2H: Uncharacterized prokaryotic Sir2 homologs from several gram positive bacterial species and Fusobacteria; and are members of the SIR2 family of proteins, silent information regulator 2 (Sir2) enzymes which catalyze NAD+-dependent protein/histone...; Region: SIR2H; cd01411 663951011145 NAD+ binding site [chemical binding]; other site 663951011146 substrate binding site [chemical binding]; other site 663951011147 putative Zn binding site [ion binding]; other site 663951011148 HMMPfam hit to PF02146, SIR2, score 4.1e-94 663951011149 PS00290 Immunoglobulins and major histocompatibility complex proteins signature. 663951011150 PS00190 Cytochrome c family heme-binding site signature. 663951011151 Domain of unknown function (DUF3885); Region: DUF3885; pfam13021 663951011152 1 probable transmembrane helix predicted for SATW20_23370 by TMHMM2.0 at aa 4-26 663951011153 Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660 663951011154 Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248 663951011155 active site 663951011156 catalytic tetrad [active] 663951011157 HMMPfam hit to PF00248, Aldo_ket_red, score 6.2e-105 663951011158 PS00063 Aldo/keto reductase family putative active site signature. 663951011159 PS00062 Aldo/keto reductase family signature 2. 663951011160 PS00798 Aldo/keto reductase family signature 1. 663951011161 Predicted transcriptional regulators [Transcription]; Region: SoxR; COG0789 663951011162 Helix-Turn-Helix DNA binding domain of the MerR-like transcription regulators YyaN and YraB; Region: HTH_YyaN; cd01109 663951011163 DNA binding residues [nucleotide binding] 663951011164 putative dimer interface [polypeptide binding]; other site 663951011165 HMMPfam hit to PF00376, MerR, score 3e-11 663951011166 Predicted helix-turn-helix motif with score 1484.000, SD 4.24 at aa 1-22, sequence MKTKEVVALMNISQDTLRYYEK 663951011167 Glycosaminoglycan (GAG) polysaccharide lyase family. This family consists of a group of secreted bacterial lyase enzymes capable of acting on glycosaminoglycans, such as hyaluronan and chondroitin, in the extracellular matrix of host tissues; Region: GAG_Lyase; cd01083 663951011168 substrate binding site [chemical binding]; other site 663951011169 catalytic residues [active] 663951011170 HMMPfam hit to PF08124, Lyase_8_N, score 1.4e-87 663951011171 HMMPfam hit to PF02278, Lyase_8, score 5e-179 663951011172 HMMPfam hit to PF02884, Lyase_8_C, score 9.8e-39 663951011173 Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane]; Region: NlpD; COG0739 663951011174 Peptidase family M23; Region: Peptidase_M23; pfam01551 663951011175 HMMPfam hit to PF01551, Peptidase_M23, score 4.4e-27 663951011176 HAD-superfamily hydrolase, subfamily IIB; Region: HAD-SF-IIB; TIGR01484 663951011177 Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cl17915 663951011178 active site 663951011179 motif I; other site 663951011180 motif II; other site 663951011181 HMMPfam hit to PF08282, Hydrolase_3, score 1.2e-05 663951011182 MAP domain; Region: MAP; pfam03642 663951011183 HMMPfam hit to PF03642, MAP, score 1.3e-46 663951011184 Alpha-acetolactate decarboxylase [Secondary metabolites biosynthesis, transport, and catabolism]; Region: AlsD; COG3527 663951011185 HMMPfam hit to PF03306, AAL_decarboxy, score 6.7e-84 663951011186 acetolactate synthase; Reviewed; Region: PRK08617 663951011187 Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035 663951011188 PYR/PP interface [polypeptide binding]; other site 663951011189 dimer interface [polypeptide binding]; other site 663951011190 TPP binding site [chemical binding]; other site 663951011191 Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205 663951011192 Thiamine pyrophosphate (TPP) enzyme family, TPP-binding module; found in many key metabolic enzymes which use TPP (also known as thiamine diphosphate) as a cofactor. These enzymes include, among others, the E1 components of the pyruvate, the acetoin and...; Region: TPP_enzymes; cl01629 663951011193 TPP-binding site [chemical binding]; other site 663951011194 HMMPfam hit to PF02775, TPP_enzyme_C, score 3.4e-68 663951011195 PS00187 Thiamine pyrophosphate enzymes signature. 663951011196 HMMPfam hit to PF00205, TPP_enzyme_M, score 1.4e-26 663951011197 HMMPfam hit to PF02776, TPP_enzyme_N, score 3.6e-61 663951011198 ATP-binding subunits of Clp protease and DnaK/DnaJ chaperones [Posttranslational modification, protein turnover, chaperones]; Region: clpA; COG0542 663951011199 The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009 663951011200 Walker A motif; other site 663951011201 ATP binding site [chemical binding]; other site 663951011202 Walker B motif; other site 663951011203 arginine finger; other site 663951011204 HMMPfam hit to PF07724, AAA_2, score 5.1e-09 663951011205 PS00017 ATP/GTP-binding site motif A (P-loop). 663951011206 Probable gene remnant. Similar to C-terminal region of Lactococcus lactis subsp. cremoris (strain SK11) DNA or RNA helicase of superfamily II UniProt:Q02V83 (EMBL:CP000430) (1560 aa) fasta scores: E()=3.8e-87,50.533% id in 469 aa 663951011207 30S ribosomal protein S9; Reviewed; Region: rpsI; PRK00132 663951011208 HMMPfam hit to PF00380, Ribosomal_S9, score 9.2e-60 663951011209 PS00360 Ribosomal protein S9 signature. 663951011210 Ribosomal protein L13. Protein L13, a large ribosomal subunit protein, is one of five proteins required for an early folding intermediate of 23S rRNA in the assembly of the large subunit. L13 is situated on the bottom of the large subunit, near the...; Region: Ribosomal_L13; cd00392 663951011211 23S rRNA interface [nucleotide binding]; other site 663951011212 L3 interface [polypeptide binding]; other site 663951011213 HMMPfam hit to PF00572, Ribosomal_L13, score 1.2e-78 663951011214 PS00783 Ribosomal protein L13 signature. 663951011215 tRNA pseudouridine synthase A; Validated; Region: truA; PRK00021 663951011216 Eukaryotic and bacterial pseudouridine synthases similar to E. coli TruA; Region: PseudoU_synth_EcTruA; cd02570 663951011217 dimerization interface 3.5A [polypeptide binding]; other site 663951011218 active site 663951011219 HMMPfam hit to PF01416, PseudoU_synth_1, score 1.8e-35 663951011220 HMMPfam hit to PF01416, PseudoU_synth_1, score 6.8e-34 663951011221 ABC-type cobalt transport system, permease component CbiQ and related transporters [Inorganic ion transport and metabolism]; Region: CbiQ; COG0619 663951011222 4 probable transmembrane helices predicted for SATW20_23540 by TMHMM2.0 at aa 29-51, 64-86, 112-134 and 244-263 663951011223 HMMPfam hit to PF02361, CbiQ, score 1e-62 663951011224 cobalt transporter ATP-binding subunit; Provisional; Region: cbiO; PRK13646 663951011225 First domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain1; cd03225 663951011226 Walker A/P-loop; other site 663951011227 ATP binding site [chemical binding]; other site 663951011228 Q-loop/lid; other site 663951011229 ABC transporter signature motif; other site 663951011230 Walker B; other site 663951011231 D-loop; other site 663951011232 H-loop/switch region; other site 663951011233 HMMPfam hit to PF00005, ABC_tran, score 2.5e-49 663951011234 PS00211 ABC transporters family signature. 663951011235 PS00017 ATP/GTP-binding site motif A (P-loop). 663951011236 cobalt transporter ATP-binding subunit; Provisional; Region: cbiO; PRK13648 663951011237 First domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain1; cd03225 663951011238 Walker A/P-loop; other site 663951011239 ATP binding site [chemical binding]; other site 663951011240 Q-loop/lid; other site 663951011241 ABC transporter signature motif; other site 663951011242 Walker B; other site 663951011243 D-loop; other site 663951011244 H-loop/switch region; other site 663951011245 HMMPfam hit to PF00005, ABC_tran, score 8.5e-54 663951011246 PS00211 ABC transporters family signature. 663951011247 PS00017 ATP/GTP-binding site motif A (P-loop). 663951011248 50S ribosomal protein L17; Validated; Region: rplQ; PRK05591 663951011249 HMMPfam hit to PF01196, Ribosomal_L17, score 2.6e-52 663951011250 PS01167 Ribosomal protein L17 signature. 663951011251 DNA-directed RNA polymerase subunit alpha; Provisional; Region: PRK05182 663951011252 N-terminal domain of the Alpha subunit of Bacterial RNA polymerase; Region: RNAP_alpha_NTD; cd06928 663951011253 alphaNTD homodimer interface [polypeptide binding]; other site 663951011254 alphaNTD - beta interaction site [polypeptide binding]; other site 663951011255 alphaNTD - beta' interaction site [polypeptide binding]; other site 663951011256 Bacterial RNA polymerase, alpha chain C terminal domain; Region: RNA_pol_A_CTD; pfam03118 663951011257 HMMPfam hit to PF03118, RNA_pol_A_CTD, score 2.1e-34 663951011258 HMMPfam hit to PF01193, RNA_pol_L, score 2.9e-25 663951011259 HMMPfam hit to PF01000, RNA_pol_A_bac, score 2.6e-54 663951011260 30S ribosomal protein S11; Validated; Region: PRK05309 663951011261 HMMPfam hit to PF00411, Ribosomal_S11, score 1.8e-72 663951011262 PS00054 Ribosomal protein S11 signature. 663951011263 30S ribosomal protein S13; Validated; Region: rpsM; PRK05179 663951011264 30S ribosomal protein S13; Region: bact_S13; TIGR03631 663951011265 HMMPfam hit to PF00416, Ribosomal_S13, score 2.3e-57 663951011266 PS00646 Ribosomal protein S13 signature. 663951011267 50S ribosomal protein L36; Reviewed; Region: rpmJ; PRK00465 663951011268 HMMPfam hit to PF00444, Ribosomal_L36, score 8.7e-19 663951011269 PS00828 Ribosomal protein L36 signature. 663951011270 S1_IF1: Translation Initiation Factor IF1, S1-like RNA-binding domain. IF1 contains an S1-like RNA-binding domain, which is found in a wide variety of RNA-associated proteins. Translation initiation includes a number of interrelated steps preceding the...; Region: S1_IF1; cd04451 663951011271 rRNA binding site [nucleotide binding]; other site 663951011272 predicted 30S ribosome binding site; other site 663951011273 HMMPfam hit to PF01176, eIF-1a, score 2e-37 663951011274 adenylate kinase; Reviewed; Region: adk; PRK00279 663951011275 Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine triphosphates (ATP) to adenosine monophosphates (AMP) and to yield adenosine diphosphates (ADP). This enzyme is required for the biosynthesis of ADP and is essential for...; Region: ADK; cd01428 663951011276 AMP-binding site [chemical binding]; other site 663951011277 ATP-AMP (Ap5A)-binding site [chemical binding]; other site 663951011278 HMMPfam hit to PF00406, ADK, score 5.1e-93 663951011279 HMMPfam hit to PF05191, ADK_lid, score 8e-23 663951011280 PS00113 Adenylate kinase signature. 663951011281 preprotein translocase subunit SecY; Reviewed; Region: secY; PRK09204 663951011282 SecY translocase; Region: SecY; pfam00344 663951011283 HMMPfam hit to PF00344, SecY, score 1.6e-197 663951011284 10 probable transmembrane helices predicted for SATW20_23640 by TMHMM2.0 at aa 17-39, 68-90, 111-133,146-168, 175-197, 217-239, 260-282, 309-331, 362-384 and 394-411 663951011285 PS00095 C-5 cytosine-specific DNA methylases C-terminal signature. 663951011286 PS00756 Protein secY signature 2. 663951011287 PS00755 Protein secY signature 1. 663951011288 50S ribosomal protein L15; Reviewed; Region: rplO; PRK05592 663951011289 HMMPfam hit to PF00256, L15, score 4.3e-11 663951011290 PS00475 Ribosomal protein L15 signature. 663951011291 HMMPfam hit to PF01305, Ribosomal_L15, score 5.5e-61 663951011292 Ribosomal protein L30, which is found in eukaryotes and prokaryotes but not in archaea, is one of the smallest ribosomal proteins with a molecular mass of about 7kDa. L30 binds the 23SrRNA as well as the 5S rRNA and is one of five ribosomal proteins that...; Region: Ribosomal_L30; cd01658 663951011293 23S rRNA binding site [nucleotide binding]; other site 663951011294 HMMPfam hit to PF00327, Ribosomal_L30, score 5e-18 663951011295 ribosomal protein S5, bacterial/organelle type; Region: rpsE_bact; TIGR01021 663951011296 Ribosomal protein S5, N-terminal domain; Region: Ribosomal_S5; pfam00333 663951011297 Ribosomal protein S5, C-terminal domain; Region: Ribosomal_S5_C; pfam03719 663951011298 HMMPfam hit to PF03719, Ribosomal_S5_C, score 1.6e-43 663951011299 HMMPfam hit to PF00333, Ribosomal_S5, score 2.4e-40 663951011300 PS00585 Ribosomal protein S5 signature. 663951011301 Ribosomal L18/L5e: L18 (L5e) is a ribosomal protein found in the central protuberance (CP) of the large subunit. L18 binds 5S rRNA and induces a conformational change that stimulates the binding of L5 to 5S rRNA. Association of 5S rRNA with 23S rRNA...; Region: Ribosomal_L18_L5e; cd00432 663951011302 5S rRNA interface [nucleotide binding]; other site 663951011303 L27 interface [polypeptide binding]; other site 663951011304 23S rRNA interface [nucleotide binding]; other site 663951011305 L5 interface [polypeptide binding]; other site 663951011306 HMMPfam hit to PF00861, Ribosomal_L18p, score 7.2e-50 663951011307 50S ribosomal protein L6; Validated; Region: rplF; PRK05498 663951011308 Ribosomal protein L6; Region: Ribosomal_L6; pfam00347 663951011309 Ribosomal protein L6; Region: Ribosomal_L6; pfam00347 663951011310 HMMPfam hit to PF00347, Ribosomal_L6, score 1.1e-31 663951011311 PS00525 Ribosomal protein L6 signature 1. 663951011312 HMMPfam hit to PF00347, Ribosomal_L6, score 1.6e-27 663951011313 30S ribosomal protein S8; Validated; Region: rpsH; PRK00136 663951011314 HMMPfam hit to PF00410, Ribosomal_S8, score 1.6e-75 663951011315 PS00053 Ribosomal protein S8 signature. 663951011316 30S ribosomal protein S14; Reviewed; Region: rpsN; PRK08061 663951011317 HMMPfam hit to PF00253, Ribosomal_S14, score 4.5e-21 663951011318 PS00527 Ribosomal protein S14 signature. 663951011319 50S ribosomal protein L5; Validated; Region: rplE; PRK00010 663951011320 Ribosomal protein L5; Region: Ribosomal_L5; pfam00281 663951011321 ribosomal L5P family C-terminus; Region: Ribosomal_L5_C; pfam00673 663951011322 HMMPfam hit to PF00673, Ribosomal_L5_C, score 3.8e-58 663951011323 HMMPfam hit to PF00281, Ribosomal_L5, score 3.9e-34 663951011324 PS00358 Ribosomal protein L5 signature. 663951011325 50S ribosomal protein L24; Reviewed; Region: rplX; PRK00004 663951011326 KOW motif of Ribosomal Protein L26; Region: KOW_RPL26; cd06089 663951011327 RNA binding site [nucleotide binding]; other site 663951011328 HMMPfam hit to PF00467, KOW, score 5.6e-11 663951011329 PS01108 Ribosomal protein L24 signature. 663951011330 50S ribosomal protein L14; Validated; Region: rplN; PRK05483 663951011331 HMMPfam hit to PF00238, Ribosomal_L14, score 9.4e-78 663951011332 PS00049 Ribosomal protein L14 signature. 663951011333 30S ribosomal protein S17; Reviewed; Region: rpsQ; PRK05610 663951011334 HMMPfam hit to PF00366, Ribosomal_S17, score 2.8e-38 663951011335 PS00056 Ribosomal protein S17 signature. 663951011336 Ribosomal L29 protein/HIP. L29 is a protein of the large ribosomal Subunit. A homolog, called heparin/heparan sulfate interacting protein (HIP), has also been identified in mammals. L29 is located on the surface of the large ribosomal subunit, where it...; Region: Ribosomal_L29_HIP; cd00427 663951011337 23S rRNA interface [nucleotide binding]; other site 663951011338 putative translocon interaction site; other site 663951011339 signal recognition particle (SRP54) interaction site; other site 663951011340 L23 interface [polypeptide binding]; other site 663951011341 trigger factor interaction site; other site 663951011342 HMMPfam hit to PF00831, Ribosomal_L29, score 3.4e-28 663951011343 Ribosomal_L16_L10e: L16 is an essential protein in the large ribosomal subunit of bacteria, mitochondria, and chloroplasts. Large subunits that lack L16 are defective in peptidyl transferase activity, peptidyl-tRNA hydrolysis activity, association with...; Region: Ribosomal_L16_L10e; cd01433 663951011344 23S rRNA interface [nucleotide binding]; other site 663951011345 5S rRNA interface [nucleotide binding]; other site 663951011346 putative antibiotic binding site [chemical binding]; other site 663951011347 L25 interface [polypeptide binding]; other site 663951011348 L27 interface [polypeptide binding]; other site 663951011349 HMMPfam hit to PF00252, Ribosomal_L16, score 6.7e-87 663951011350 PS00701 Ribosomal protein L16 signature 2. 663951011351 PS00586 Ribosomal protein L16 signature 1. 663951011352 30S ribosomal protein S3; Reviewed; Region: rpsC; PRK00310 663951011353 K homology RNA-binding (KH) domain of the prokaryotic 30S small ribosomal subunit protein S3. S3 is part of the head region of the 30S ribosomal subunit and is believed to interact with mRNA as it threads its way from the latch into the channel. The KH...; Region: 30S_S3_KH; cd02412 663951011354 G-X-X-G motif; other site 663951011355 Ribosomal protein S3, C-terminal domain; Region: Ribosomal_S3_C; pfam00189 663951011356 HMMPfam hit to PF00189, Ribosomal_S3_C, score 9.8e-50 663951011357 PS00548 Ribosomal protein S3 signature. 663951011358 HMMPfam hit to PF07650, KH_2, score 1.3e-21 663951011359 HMMPfam hit to PF00417, Ribosomal_S3_N, score 7.7e-31 663951011360 Ribosomal protein L22/L17e. L22 (L17 in eukaryotes) is a core protein of the large ribosomal subunit. It is the only ribosomal protein that interacts with all six domains of 23S rRNA, and is one of the proteins important for directing the proper...; Region: Ribosomal_L22; cd00336 663951011361 putative translocon binding site; other site 663951011362 protein-rRNA interface [nucleotide binding]; other site 663951011363 HMMPfam hit to PF00237, Ribosomal_L22, score 1.1e-60 663951011364 PS00464 Ribosomal protein L22 signature. 663951011365 30S ribosomal protein S19; Reviewed; Region: rpsS; PRK00357 663951011366 HMMPfam hit to PF00203, Ribosomal_S19, score 5.8e-52 663951011367 PS00323 Ribosomal protein S19 signature. 663951011368 50S ribosomal protein L2; Validated; Region: rplB; PRK09374 663951011369 Ribosomal Proteins L2, RNA binding domain; Region: Ribosomal_L2; pfam00181 663951011370 Ribosomal Proteins L2, C-terminal domain; Region: Ribosomal_L2_C; pfam03947 663951011371 HMMPfam hit to PF03947, Ribosomal_L2_C, score 1e-92 663951011372 PS00467 Ribosomal protein L2 signature. 663951011373 HMMPfam hit to PF00181, Ribosomal_L2, score 4.3e-47 663951011374 50S ribosomal protein L23; Reviewed; Region: rplW; PRK05738 663951011375 HMMPfam hit to PF00276, Ribosomal_L23, score 2.8e-34 663951011376 50S ribosomal protein L4; Provisional; Region: rplD; PRK05319 663951011377 HMMPfam hit to PF00573, Ribosomal_L4, score 9.9e-82 663951011378 50S ribosomal protein L3; Validated; Region: rplC; PRK00001 663951011379 HMMPfam hit to PF00297, Ribosomal_L3, score 8.4e-88 663951011380 PS00474 Ribosomal protein L3 signature. 663951011381 30S ribosomal protein S10; Reviewed; Region: rpsJ; PRK00596 663951011382 HMMPfam hit to PF00338, Ribosomal_S10, score 2e-60 663951011383 PS00361 Ribosomal protein S10 signature. 663951011384 4 probable transmembrane helices predicted for SATW20_23860 by TMHMM2.0 at aa 7-26, 36-58, 65-87 and 91-113 663951011385 Xanthine/uracil/vitamin C permease [Nucleotide transport and metabolism]; Region: COG2252 663951011386 13 probable transmembrane helices predicted for SATW20_23870 by TMHMM2.0 at aa 20-42, 57-76, 83-105,110-132, 141-163, 178-195, 202-221, 252-274, 295-317,322-344, 349-371, 391-413 and 425-442 663951011387 HMMPfam hit to PF00860, Xan_ur_permease, score 2.3e-25 663951011388 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 663951011389 DNA topoisomerase III; Provisional; Region: PRK07726 663951011390 TOPRIM_TopoIA_TopoIII: The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to topoisomerase III. Type IA DNA topoisomerases remove (relax) negative supercoils in the DNA by: cleaving...; Region: TOPRIM_TopoIA_TopoIII; cd03362 663951011391 active site 663951011392 putative interdomain interaction site [polypeptide binding]; other site 663951011393 putative metal-binding site [ion binding]; other site 663951011394 putative nucleotide binding site [chemical binding]; other site 663951011395 DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cd00186 663951011396 domain I; other site 663951011397 DNA binding groove [nucleotide binding] 663951011398 phosphate binding site [ion binding]; other site 663951011399 domain II; other site 663951011400 domain III; other site 663951011401 nucleotide binding site [chemical binding]; other site 663951011402 catalytic site [active] 663951011403 domain IV; other site 663951011404 Zn-finger domain associated with topoisomerase type I [DNA replication, recombination, and repair]; Region: TopA; COG0551 663951011405 PS00196 Type-1 copper (blue) proteins signature. 663951011406 HMMPfam hit to PF01396, zf-C4_Topoisom, score 0.0072 663951011407 HMMPfam hit to PF01131, Topoisom_bac, score 1.8e-90 663951011408 HMMPfam hit to PF01751, Toprim, score 1.5e-18 663951011409 N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301 663951011410 Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302 663951011411 Coenzyme A binding pocket [chemical binding]; other site 663951011412 HMMPfam hit to PF00583, Acetyltransf_1, score 1.5e-06 663951011413 Putative glucose uptake permease [Carbohydrate transport and metabolism]; Region: GlcU; COG4975 663951011414 L-rhamnose-proton symport protein (RhaT); Region: RhaT; cl05728 663951011415 9 probable transmembrane helices predicted for SATW20_23900 by TMHMM2.0 at aa 7-29, 34-53, 60-77, 114-136,157-179, 184-201, 208-230, 235-257 and 269-286 663951011416 HMMPfam hit to PF06800, Sugar_transport, score 4.4e-138 663951011417 Predicted permeases [General function prediction only]; Region: COG0679 663951011418 10 probable transmembrane helices predicted for SATW20_23910 by TMHMM2.0 at aa 5-24, 37-54, 64-86, 95-117,122-144, 164-186, 196-217, 229-248, 258-275 and 282-304 663951011419 HMMPfam hit to PF03547, Mem_trans, score 2.6e-09 663951011420 4 probable transmembrane helices predicted for SATW20_23930 by TMHMM2.0 at aa 4-21, 28-50, 55-73 and 82-104 663951011421 Cation/multidrug efflux pump [Defense mechanisms]; Region: AcrB; COG0841 663951011422 HMMPfam hit to PF00873, ACR_tran, score 1.1e-151 663951011423 12 probable transmembrane helices predicted for SATW20_23940 by TMHMM2.0 at aa 13-32, 369-391, 398-415,420-438, 476-498, 508-530, 561-583, 886-908, 913-935,945-967, 988-1008 and 1023-1045 663951011424 Peptidoglycan interpeptide bridge formation enzyme [Cell wall/membrane/envelope biogenesis]; Region: COG2348 663951011425 Acetyltransferase (GNAT) domain; Region: Acetyltransf_6; pfam13480 663951011426 HMMPfam hit to PF02388, FemAB, score 2.1e-37 663951011427 Glyoxalase-like domain; Region: Glyoxalase_3; pfam13468 663951011428 Winged helix DNA-binding domain; Region: HTH_27; pfam13463 663951011429 HMMPfam hit to PF01047, MarR, score 1e-15 663951011430 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 663951011431 Major Facilitator Superfamily; Region: MFS_1; pfam07690 663951011432 putative substrate translocation pore; other site 663951011433 12 probable transmembrane helices predicted for SATW20_23980 by TMHMM2.0 at aa 20-42, 52-71, 83-100,113-135, 142-164, 168-190, 220-242, 252-274, 283-302,307-326, 347-369 and 374-393 663951011434 HMMPfam hit to PF07690, MFS_1, score 8.9e-47 663951011435 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 663951011436 staphylococcal accessory regulator family; Region: Staph_reg_Sar; TIGR01889 663951011437 Transcriptional regulators [Transcription]; Region: MarR; COG1846 663951011438 HMMPfam hit to PF01047, MarR, score 0.002 663951011439 molybdenum cofactor biosynthesis protein A, bacterial; Region: moaA; TIGR02666 663951011440 Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335 663951011441 FeS/SAM binding site; other site 663951011442 Molybdenum Cofactor Synthesis C; Region: Mob_synth_C; pfam06463 663951011443 HMMPfam hit to PF06463, Mob_synth_C, score 9.2e-48 663951011444 HMMPfam hit to PF04055, Radical_SAM, score 9.6e-13 663951011445 molybdopterin-guanine dinucleotide biosynthesis protein MobA; Reviewed; Region: mobA; PRK00317 663951011446 MobA catalyzes the formation of molybdopterin guanine dinucleotide; Region: MobA; cd02503 663951011447 GTP binding site; other site 663951011448 Ubiquitin domain of MoaD-like proteins; Region: MoaD; cd00754 663951011449 MoaE interaction surface [polypeptide binding]; other site 663951011450 MoeB interaction surface [polypeptide binding]; other site 663951011451 thiocarboxylated glycine; other site 663951011452 HMMPfam hit to PF02597, ThiS, score 8.3e-21 663951011453 MoaE family. Members of this family are involved in biosynthesis of the molybdenum cofactor (Moco), an essential cofactor for a diverse group of redox enzymes. Moco biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea and...; Region: MoaE; cd00756 663951011454 MoaE homodimer interface [polypeptide binding]; other site 663951011455 MoaD interaction [polypeptide binding]; other site 663951011456 active site residues [active] 663951011457 HMMPfam hit to PF02391, MoaE, score 8.7e-56 663951011458 Molybdopterin-guanine dinucleotide biosynthesis protein [Coenzyme metabolism]; Region: MobB; COG1763 663951011459 HMMPfam hit to PF03205, MobB, score 2.1e-40 663951011460 PS00017 ATP/GTP-binding site motif A (P-loop). 663951011461 Molybdopterin biosynthesis enzyme [Coenzyme metabolism]; Region: MoeA; COG0303 663951011462 MoeA family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF), an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea and...; Region: MoeA; cd00887 663951011463 dimer interface [polypeptide binding]; other site 663951011464 putative functional site; other site 663951011465 putative MPT binding site; other site 663951011466 HMMPfam hit to PF03454, MoeA_C, score 4.9e-20 663951011467 HMMPfam hit to PF00994, MoCF_biosynth, score 1.4e-45 663951011468 HMMPfam hit to PF03453, MoeA_N, score 3.3e-81 663951011469 MoaC family, prokaryotic and eukaryotic. Members of this family are involved in molybdenum cofactor (Moco) biosynthesis, an essential cofactor of a diverse group of redox enzymes. MoaC, a small hexameric protein, converts, together with MoaA, a guanosine...; Region: MoaC_PE; cd01420 663951011470 trimer interface [polypeptide binding]; other site 663951011471 dimer interface [polypeptide binding]; other site 663951011472 putative active site [active] 663951011473 Predicted helix-turn-helix motif with score 1001.000, SD 2.60 at aa 7-28, sequence INQQGHAKMVDVSDKQITKRTA 663951011474 HMMPfam hit to PF01967, MoaC, score 7.9e-74 663951011475 MogA_MoaB family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF) an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea; Region: MogA_MoaB; cd00886 663951011476 MPT binding site; other site 663951011477 trimer interface [polypeptide binding]; other site 663951011478 HMMPfam hit to PF00994, MoCF_biosynth, score 4.6e-37 663951011479 PS01078 Molybdenum cofactor biosynthesis proteins signature 1. 663951011480 thiamine/molybdopterin biosynthesis ThiF/MoeB-like protein; Validated; Region: PRK07688 663951011481 ThiF_MoeB_HesA. Family of E1-like enzymes involved in molybdopterin and thiamine biosynthesis family. The common reaction mechanism catalyzed by MoeB and ThiF, like other E1 enzymes, begins with a nucleophilic attack of the C-terminal carboxylate of MoaD...; Region: ThiF_MoeB_HesA_family; cd00757 663951011482 ATP binding site [chemical binding]; other site 663951011483 substrate interface [chemical binding]; other site 663951011484 HMMPfam hit to PF05237, MoeZ_MoeB, score 4.1e-31 663951011485 PS00017 ATP/GTP-binding site motif A (P-loop). 663951011486 HMMPfam hit to PF00899, ThiF, score 1.3e-49 663951011487 ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201 663951011488 putative bacteriocin export ABC transporter, lactococcin 972 group; Region: L_ocin_972_ABC; TIGR03608 663951011489 Walker A/P-loop; other site 663951011490 ATP binding site [chemical binding]; other site 663951011491 Q-loop/lid; other site 663951011492 ABC transporter signature motif; other site 663951011493 Walker B; other site 663951011494 D-loop; other site 663951011495 H-loop/switch region; other site 663951011496 HMMPfam hit to PF00005, ABC_tran, score 4.1e-42 663951011497 PS00211 ABC transporters family signature. 663951011498 PS00017 ATP/GTP-binding site motif A (P-loop). 663951011499 ABC-type sulfate transport system, permease component [Posttranslational modification, protein turnover, chaperones]; Region: CysU; COG0555 663951011500 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 663951011501 dimer interface [polypeptide binding]; other site 663951011502 conserved gate region; other site 663951011503 putative PBP binding loops; other site 663951011504 ABC-ATPase subunit interface; other site 663951011505 HMMPfam hit to PF00528, BPD_transp_1, score 5.9e-17 663951011506 5 probable transmembrane helices predicted for SATW20_24100 by TMHMM2.0 at aa 10-32, 45-67, 82-104,145-167 and 193-215 663951011507 ABC-type molybdate transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: ModA; COG0725 663951011508 Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134 663951011509 substrate binding pocket [chemical binding]; other site 663951011510 membrane-bound complex binding site; other site 663951011511 hinge residues; other site 663951011512 HMMPfam hit to PF01547, SBP_bac_1, score 1.8e-09 663951011513 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 663951011514 formate dehydrogenase accessory protein; Reviewed; Region: PRK00724 663951011515 HMMPfam hit to PF02634, FdhD-NarQ, score 6.4e-88 663951011516 N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301 663951011517 Coenzyme A binding pocket [chemical binding]; other site 663951011518 HMMPfam hit to PF00583, Acetyltransf_1, score 1.3e-07 663951011519 Uncharacterized conserved protein [General function prediction only]; Region: BioY; COG1268 663951011520 HMMPfam hit to PF02632, BioY, score 6.1e-30 663951011521 6 probable transmembrane helices predicted for SATW20_24140 by TMHMM2.0 at aa 7-25, 29-48, 55-74, 78-100,112-134 and 149-171 663951011522 nuc_hydro_ TvIAG: Nucleoside hydrolases similar to the Inosine-adenosine-guanosine-preferring nucleoside hydrolase from Trypanosoma vivax. Nucleoside hydrolases cleave the N-glycosidic bond in nucleosides generating ribose and the respective base; Region: nuc_hydro_TvIAG; cd02647 663951011523 active site 663951011524 dimerization interface [polypeptide binding]; other site 663951011525 HMMPfam hit to PF01156, IU_nuc_hydro, score 3.8e-22 663951011526 ABC-type Fe3+-hydroxamate transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: FepB; COG0614 663951011527 Helical backbone metal receptor (TroA-like domain). These proteins have been shown to function in the ABC transport of ferric siderophores and metal ions such as Mn2+, Fe3+, Cu2+ and/or Zn2+. Their ligand binding site is formed in the interface between...; Region: TroA-like; cl00262 663951011528 intersubunit interface [polypeptide binding]; other site 663951011529 HMMPfam hit to PF01497, Peripla_BP_2, score 1.4e-34 663951011530 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 663951011531 Acyl-CoA dehydrogenases [Lipid metabolism]; Region: CaiA; COG1960 663951011532 Acyl-CoA dehydrogenase, N-terminal domain; Region: Acyl-CoA_dh_N; pfam02771 663951011533 Acyl-CoA dehydrogenase; Region: ACAD; cd00567 663951011534 HMMPfam hit to PF00441, Acyl-CoA_dh_1, score 2.6e-05 663951011535 HMMPfam hit to PF02770, Acyl-CoA_dh_M, score 5.4e-05 663951011536 Urea transporter [Amino acid transport and metabolism]; Region: Utp; COG4413 663951011537 HMMPfam hit to PF03253, UT, score 7.8e-153 663951011538 8 probable transmembrane helices predicted for SATW20_24180 by TMHMM2.0 at aa 21-43, 89-106, 113-135,171-193, 198-215, 225-242, 249-267 and 272-294 663951011539 Urease gamma-subunit; Urease is a nickel-dependent metalloenzyme that catalyzes the hydrolysis of urea to form ammonia and carbon dioxide. Nickel-dependent ureases are found in bacteria, archaea, fungi and plants. Their primary role is to allow the use...; Region: Urease_gamma; cd00390 663951011540 alpha-gamma subunit interface [polypeptide binding]; other site 663951011541 beta-gamma subunit interface [polypeptide binding]; other site 663951011542 HMMPfam hit to PF00547, Urease_gamma, score 1.6e-58 663951011543 Urease beta-subunit; Urease is a nickel-dependent metalloenzyme that catalyzes the hydrolysis of urea to form ammonia and carbon dioxide. Nickel-dependent ureases are found in bacteria, archaea, fungi and plants. Their primary role is to allow the use of...; Region: Urease_beta; cd00407 663951011544 gamma-beta subunit interface [polypeptide binding]; other site 663951011545 alpha-beta subunit interface [polypeptide binding]; other site 663951011546 HMMPfam hit to PF00699, Urease_beta, score 1.7e-66 663951011547 urease subunit alpha; Reviewed; Region: ureC; PRK13207 663951011548 Urease alpha-subunit; Urease is a nickel-dependent metalloenzyme that catalyzes the hydrolysis of urea to form ammonia and carbon dioxide. Nickel-dependent ureases are found in bacteria, fungi and plants. Their primary role is to allow the use of...; Region: Urease_alpha; cd00375 663951011549 subunit interactions [polypeptide binding]; other site 663951011550 active site 663951011551 flap region; other site 663951011552 HMMPfam hit to PF00449, Urease_alpha, score 3.3e-84 663951011553 PS00017 ATP/GTP-binding site motif A (P-loop). 663951011554 HMMPfam hit to PF01979, Amidohydro_1, score 3.3e-92 663951011555 PS01120 Urease nickel ligands signature. 663951011556 PS00145 Urease active site. 663951011557 urease accessory protein UreE; Provisional; Region: ureE; PRK13261 663951011558 UreE urease accessory protein. UreE is a metallochaperone assisting the insertion of a Ni2+ ion in the active site of urease, an important step in the in vivo assembly of urease, an enzyme that hydrolyses urea into ammonia and carbamic acid. The...; Region: UreE; cd00571 663951011559 dimer interface [polypeptide binding]; other site 663951011560 catalytic residues [active] 663951011561 HMMPfam hit to PF02814, UreE_N, score 9.3e-27 663951011562 HMMPfam hit to PF05194, UreE_C, score 7.8e-36 663951011563 Urease accessory protein UreF [Posttranslational modification, protein turnover, chaperones]; Region: UreF; COG0830 663951011564 UreF; Region: UreF; pfam01730 663951011565 HMMPfam hit to PF01730, UreF, score 4.6e-73 663951011566 The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203 663951011567 HMMPfam hit to PF02492, cobW, score 1.1e-72 663951011568 PS00017 ATP/GTP-binding site motif A (P-loop). 663951011569 Urease accessory protein UreH [Posttranslational modification, protein turnover, chaperones]; Region: UreH; COG0829 663951011570 HMMPfam hit to PF01774, UreD, score 5.7e-60 663951011571 staphylococcal accessory regulator family; Region: Staph_reg_Sar; TIGR01889 663951011572 staphylococcal accessory regulator family; Region: Staph_reg_Sar; TIGR01889 663951011573 staphylococcal accessory regulator family; Region: Staph_reg_Sar; TIGR01889 663951011574 Helix-turn-helix domain; Region: HTH_18; pfam12833 663951011575 Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165 663951011576 Predicted helix-turn-helix motif with score 1261.000, SD 3.48 at aa 313-334, sequence YTIKQIIQRLGVNPENLHIIVT 663951011577 HMMPfam hit to PF00165, HTH_AraC, score 2.1e-06 663951011578 Surface antigen [General function prediction only]; Region: COG3942 663951011579 CHAP domain; Region: CHAP; pfam05257 663951011580 HMMPfam hit to PF05257, CHAP, score 2.6e-47 663951011581 Na+/H+ antiporter NhaC; Region: antiport_nhaC; TIGR00931 663951011582 10 probable transmembrane helices predicted for SATW20_24310 by TMHMM2.0 at aa 7-29, 33-53, 66-88, 108-130,187-209, 229-251, 258-276, 310-332, 352-383 and 433-455 663951011583 HMMPfam hit to PF03553, Na_H_antiporter, score 4.3e-96 663951011584 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; Region: NAD_Gly3P_dh_N; pfam01210 663951011585 NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain; Region: Octopine_DH; pfam02317 663951011586 HMMPfam hit to PF02317, Octopine_DH, score 4.2e-67 663951011587 Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3296 663951011588 3 probable transmembrane helices predicted for SATW20_24330 by TMHMM2.0 at aa 22-44, 65-87 and 92-123 663951011589 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 663951011590 Surface antigen [General function prediction only]; Region: COG3942 663951011591 CHAP domain; Region: CHAP; pfam05257 663951011592 HMMPfam hit to PF05257, CHAP, score 5e-44 663951011593 Putative D-isomer specific 2-hydroxyacid dehydrogenases, NAD-binding and catalytic domains; Region: 2-Hacid_dh_13; cd12178 663951011594 Lactate dehydrogenase and related dehydrogenases [Energy production and conversion / Coenzyme metabolism / General function prediction only]; Region: LdhA; COG1052 663951011595 putative ligand binding site [chemical binding]; other site 663951011596 putative NAD binding site [chemical binding]; other site 663951011597 catalytic site [active] 663951011598 HMMPfam hit to PF00389, 2-Hacid_dh, score 1.6e-36 663951011599 HMMPfam hit to PF02826, 2-Hacid_dh_C, score 1.2e-87 663951011600 PS00017 ATP/GTP-binding site motif A (P-loop). 663951011601 hypothetical protein; Provisional; Region: PRK06753 663951011602 ubiquinone biosynthesis hydroxylase family protein; Provisional; Region: PRK07608; cl17314 663951011603 HMMPfam hit to PF01266, DAO, score 5.1e-07 663951011604 Beta- N-acetylglucosaminidase [Carbohydrate transport and metabolism]; Region: LytD; COG4193 663951011605 Lysozyme subfamily 2; Region: LYZ2; smart00047 663951011606 HMMPfam hit to PF01832, Glucosaminidase, score 8.1e-41 663951011607 Predicted helix-turn-helix motif with score 1098.000, SD 2.93 at aa 84-105, sequence MKYMDITEKVPMSESEVNQLLK 663951011608 1 probable transmembrane helix predicted for SATW20_24370 by TMHMM2.0 at aa 7-26 663951011609 2 probable transmembrane helices predicted for SATW20_24380 by TMHMM2.0 at aa 12-34 and 54-76 663951011610 Uncharacterized conserved protein [Function unknown]; Region: COG2427 663951011611 HMMPfam hit to PF07849, DUF1641, score 6.9e-12 663951011612 Uncharacterized anaerobic dehydrogenase [General function prediction only]; Region: COG3383 663951011613 2Fe-2S iron-sulfur cluster binding domain; Region: Fer2_4; pfam13510 663951011614 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region; Region: NADH-G_4Fe-4S_3; pfam10588 663951011615 4Fe-4S binding domain; Region: Fer4; pfam00037 663951011616 Formate dehydrogenase H (Formate-Dh-H) catalyzes the reversible oxidation of formate to CO2 with the release of a proton and two electrons. It is a component of the anaerobic formate hydrogen lyase complex. The E. coli formate dehydrogenase H (Fdh-H) is...; Region: MopB_Formate-Dh-H; cd02753 663951011617 [4Fe-4S] binding site [ion binding]; other site 663951011618 molybdopterin cofactor binding site; other site 663951011619 Formate dehydrogenase N, alpha subunit (Formate-Dh-Na) is a major component of nitrate respiration in bacteria such as in the E. coli formate dehydrogenase N (Fdh-N). Fdh-N is a membrane protein that is a complex of three different subunits and is the...; Region: MopB_CT_Formate-Dh-Na-like; cd02792 663951011620 molybdopterin cofactor binding site; other site 663951011621 HMMPfam hit to PF01568, Molydop_binding, score 2.8e-21 663951011622 HMMPfam hit to PF00384, Molybdopterin, score 1.2e-94 663951011623 HMMPfam hit to PF04879, Molybdop_Fe4S4, score 3.9e-25 663951011624 PS00551 Prokaryotic molybdopterin oxidoreductases signature 1. 663951011625 HMMPfam hit to PF00037, Fer4, score 4e-06 663951011626 PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature. 663951011627 HMMPfam hit to PF00037, Fer4, score 0.0027 663951011628 HMMPfam hit to PF00111, Fer2, score 5.7e-05 663951011629 Cell envelope-related transcriptional attenuator domain; Region: LytR_cpsA_psr; cl00581 663951011630 HMMPfam hit to PF03816, LytR_cpsA_psr, score 9.5e-76 663951011631 1 probable transmembrane helix predicted for SATW20_24410 by TMHMM2.0 at aa 15-34 663951011632 Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family [Carbohydrate transport and metabolism]; Region: SuhB; COG0483 663951011633 Inositol-monophosphatase-like domains. This family of phosphatases is dependent on bivalent metal ions such as Mg++, and many members are inhibited by Li+ (which is thought to displace a bivalent ion in the active site). Substrates include fructose-1; Region: IMPase_like; cd01637 663951011634 active site 663951011635 HMMPfam hit to PF00459, Inositol_P, score 1.1e-27 663951011636 Predicted transcriptional regulator [Transcription]; Region: COG2378 663951011637 HTH domain; Region: HTH_11; pfam08279 663951011638 HMMPfam hit to PF08279, HTH_11, score 4.3e-15 663951011639 Predicted helix-turn-helix motif with score 1386.000, SD 3.91 at aa 20-41, sequence MTALELAKYCNVSKRTILRDID 663951011640 Probable gene remnant 663951011641 CAAX protease self-immunity; Region: Abi; pfam02517 663951011642 7 probable transmembrane helices predicted for SATW20_24450 by TMHMM2.0 at aa 19-41, 51-73, 92-114,139-161, 173-192, 196-215 and 222-244 663951011643 HMMPfam hit to PF02517, Abi, score 1.5e-16 663951011644 Transcriptional regulators [Transcription]; Region: RpiR; COG1737 663951011645 Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418 663951011646 RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013 663951011647 putative active site [active] 663951011648 HMMPfam hit to PF01418, HTH_6, score 1.1e-26 663951011649 Predicted helix-turn-helix motif with score 978.000,SD 2.52 at aa 36-57, sequence MRSQDLASLLDISTSSVIRFSK 663951011650 HMMPfam hit to PF01380, SIS, score 1.1e-15 663951011651 Gamma-aminobutyrate permease and related permeases [Amino acid transport and metabolism]; Region: AnsP; COG1113 663951011652 HMMPfam hit to PF00324, AA_permease, score 3.8e-124 663951011653 11 probable transmembrane helices predicted for SATW20_24480 by TMHMM2.0 at aa 15-32, 39-61, 122-141,153-175, 195-217, 237-259, 269-291, 329-351, 361-383,403-425 and 430-449 663951011654 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 663951011655 PS00218 Amino acid permeases signature. 663951011656 3 probable transmembrane helices predicted for SATW20_24490 by TMHMM2.0 at aa 5-27, 36-58 and 73-106 663951011657 2 probable transmembrane helices predicted for SATW20_24500 by TMHMM2.0 at aa 5-24 and 39-58 663951011658 2 probable transmembrane helices predicted for SATW20_24510 by TMHMM2.0 at aa 4-26 and 39-58 663951011659 Predicted phosphatase/phosphohexomutase [General function prediction only]; Region: COG0637 663951011660 Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427 663951011661 active site 663951011662 motif I; other site 663951011663 motif II; other site 663951011664 HMMPfam hit to PF00702, Hydrolase, score 2e-29 663951011665 Predicted Na+-dependent transporter [General function prediction only]; Region: COG0385 663951011666 Sodium Bile acid symporter family; Region: SBF; pfam01758 663951011667 8 probable transmembrane helices predicted for SATW20_24530 by TMHMM2.0 at aa 15-37, 50-70, 80-102,107-129, 144-166, 173-195, 205-227 and 248-270 663951011668 HMMPfam hit to PF01758, SBF, score 4e-55 663951011669 PTS system, alpha-glucoside-specific IIBC component; Region: PTS-IIBC-alpha; TIGR02005 663951011670 Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263 663951011671 PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212 663951011672 active site turn [active] 663951011673 phosphorylation site [posttranslational modification] 663951011674 PS00017 ATP/GTP-binding site motif A (P-loop). 663951011675 HMMPfam hit to PF00367, PTS_EIIB, score 2.3e-14 663951011676 PS01035 PTS EIIB domains cysteine phosphorylation site signature. 663951011677 10 probable transmembrane helices predicted for SATW20_24550 by TMHMM2.0 at aa 7-29, 56-78, 85-107,127-149, 170-192, 202-219, 304-321, 326-343, 350-372 and 382-404 663951011678 HMMPfam hit to PF02378, PTS_EIIC, score 4.5e-66 663951011679 PS00079 Multicopper oxidases signature 1. 663951011680 Transcriptional regulators [Transcription]; Region: RpiR; COG1737 663951011681 Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418 663951011682 RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013 663951011683 putative active site [active] 663951011684 HMMPfam hit to PF01418, HTH_6, score 8.1e-16 663951011685 Predicted helix-turn-helix motif with score 1106.000, SD 2.95 at aa 35-56, sequence MKIQDLAQFTHASNATIHRFTR 663951011686 HMMPfam hit to PF01380, SIS, score 2.1e-33 663951011687 Putative hydrophobic ligand-binding SRPBCC domain of Micromonospora echinospora CalC, human Aha1, and related proteins; Region: SRPBCC_CalC_Aha1-like; cd07814 663951011688 putative hydrophobic ligand binding site [chemical binding]; other site 663951011689 HMMPfam hit to PF08327, AHSA1, score 2.5e-17 663951011690 Na+/H+ antiporter [Energy production and conversion]; Region: NhaC; COG1757 663951011691 HMMPfam hit to PF03553, Na_H_antiporter, score 4.6e-68 663951011692 10 probable transmembrane helices predicted for SATW20_24580 by TMHMM2.0 at aa 7-29, 33-50, 71-90, 110-132,191-213, 228-250, 252-274, 289-311, 373-395 and 400-422 663951011693 6 probable transmembrane helices predicted for SATW20_24590 by TMHMM2.0 at aa 3-25, 29-51, 64-86, 92-114,134-156 and 160-182 663951011694 oxidoreductase; Provisional; Region: PRK07985 663951011695 Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931 663951011696 NAD(P) binding site [chemical binding]; other site 663951011697 active site 663951011698 HMMPfam hit to PF00106, adh_short, score 3.9e-17 663951011699 PS00061 Short-chain dehydrogenases/reductases family signature. 663951011700 M20 Peptidase Aminoacyclase-1 YxeP-like proteins, including YxeP, YtnL, YjiB and HipO2; Region: M20_Acy1_YxeP_like; cd05669 663951011701 amidohydrolase; Region: amidohydrolases; TIGR01891 663951011702 metal binding site [ion binding]; metal-binding site 663951011703 dimer interface [polypeptide binding]; other site 663951011704 HMMPfam hit to PF01546, Peptidase_M20, score 9.7e-48 663951011705 HMMPfam hit to PF07687, M20_dimer, score 3.1e-06 663951011706 imidazolonepropionase; Validated; Region: PRK09356 663951011707 Imidazolonepropionase/imidazolone-5-propionate hydrolase (Imidazolone-5PH) catalyzes the third step in the histidine degradation pathway, the hydrolysis of (S)-3-(5-oxo-4,5-dihydro-3H-imidazol-4-yl)propanoate to N-formimidoyl-L-glutamate. In bacteria; Region: Imidazolone-5PH; cd01296 663951011708 active site 663951011709 HMMPfam hit to PF01979, Amidohydro_1, score 7.2e-06 663951011710 urocanate hydratase; Provisional; Region: PRK05414 663951011711 HMMPfam hit to PF01175, Urocanase, score 0 663951011712 Transcriptional regulator [Transcription]; Region: LysR; COG0583 663951011713 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 663951011714 The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466 663951011715 dimerization interface [polypeptide binding]; other site 663951011716 HMMPfam hit to PF00126, HTH_1, score 1.6e-16 663951011717 Predicted helix-turn-helix motif with score 1212.000, SD 3.31 at aa 16-37, sequence NSFTKAAQFLHISQPSLTATIK 663951011718 PS00044 Bacterial regulatory proteins, lysR family signature. 663951011719 HMMPfam hit to PF03466, LysR_substrate, score 1.7e-28 663951011720 fosfomycin resistance protein FosB; Provisional; Region: PRK04101 663951011721 FosB, a fosfomycin resistance protein, catalyzes the Mg(II) dependent addition of L-cysteine to the epoxide ring of fosfomycin; Region: FosB; cd08363 663951011722 putative active site [active] 663951011723 putative Mg binding site [ion binding]; other site 663951011724 HMMPfam hit to PF00903, Glyoxalase, score 4e-18 663951011725 formimidoylglutamase; Provisional; Region: PRK13775 663951011726 Formimidoylglutamase or HutE; Region: Formimidoylglutamase; cd09988 663951011727 putative active site [active] 663951011728 putative metal binding site [ion binding]; other site 663951011729 HMMPfam hit to PF00491, Arginase, score 2e-11 663951011730 PS00148 Arginase family signature 2. 663951011731 PS00147 Arginase family signature 1. 663951011732 Predicted metal-dependent membrane protease [General function prediction only]; Region: COG1266 663951011733 8 probable transmembrane helices predicted for SATW20_24670 by TMHMM2.0 at aa 7-29, 41-63, 83-105,115-137, 150-172, 176-195, 202-221 and 231-253 663951011734 HMMPfam hit to PF02517, Abi, score 0.00029 663951011735 RPI_A: Ribose 5-phosphate isomerase type A (RPI_A) subfamily; RPI catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate, the first step of the non-oxidative branch of the pentose phosphate pathway. This reaction leads to the...; Region: RPI_A; cd01398 663951011736 tetramer (dimer of dimers) interface [polypeptide binding]; other site 663951011737 active site 663951011738 dimer interface [polypeptide binding]; other site 663951011739 HMMPfam hit to PF06026, Rib_5-P_isom_A, score 1.8e-95 663951011740 Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2258 663951011741 MOSC domain; Region: MOSC; pfam03473 663951011742 3-alpha domain; Region: 3-alpha; pfam03475 663951011743 HMMPfam hit to PF03473, MOSC, score 1.4e-42 663951011744 HMMPfam hit to PF03475, 3-alpha, score 3.6e-18 663951011745 galactose mutarotase_like; Region: galactose_mutarotase_like; cd09019 663951011746 active site 663951011747 catalytic residues [active] 663951011748 HMMPfam hit to PF01263, Aldose_epim, score 1e-100 663951011749 PS00545 Aldose 1-epimerase putative active site. 663951011750 Uncharacterized conserved protein [Function unknown]; Region: COG1742 663951011751 HMMPfam hit to PF02694, UPF0060, score 2.7e-53 663951011752 4 probable transmembrane helices predicted for SATW20_24710 by TMHMM2.0 at aa 4-26, 33-55, 60-79 and 86-105 663951011753 ABC-type Na+ efflux pump, permease component [Energy production and conversion / Inorganic ion transport and metabolism]; Region: NatB; COG1668 663951011754 7 probable transmembrane helices predicted for SATW20_24720 by TMHMM2.0 at aa 21-38, 178-200, 235-257,277-299, 312-331, 336-355 and 367-386 663951011755 ABC-type uncharacterized transport system, ATPase component [General function prediction only]; Region: COG4152 663951011756 ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201 663951011757 Walker A/P-loop; other site 663951011758 ATP binding site [chemical binding]; other site 663951011759 Q-loop/lid; other site 663951011760 ABC transporter signature motif; other site 663951011761 Walker B; other site 663951011762 D-loop; other site 663951011763 H-loop/switch region; other site 663951011764 Domain of unknown function (DUF4162); Region: DUF4162; pfam13732 663951011765 HMMPfam hit to PF00005, ABC_tran, score 1.1e-54 663951011766 PS00211 ABC transporters family signature. 663951011767 PS00017 ATP/GTP-binding site motif A (P-loop). 663951011768 Predicted membrane protein [Function unknown]; Region: COG3152 663951011769 HMMPfam hit to PF05656, DUF805, score 7e-64 663951011770 4 probable transmembrane helices predicted for SATW20_24740 by TMHMM2.0 at aa 36-58, 68-90, 110-129 and 144-166 663951011771 Alkyladenine DNA glycosylase catalyzes the first step in base excision repair; Region: AAG; cd00540 663951011772 active site 663951011773 DNA binding site [nucleotide binding] 663951011774 HMMPfam hit to PF02245, Pur_DNA_glyco, score 1.4e-43 663951011775 Sodium/glutamate symporter; Region: Glt_symporter; pfam03616 663951011776 HMMPfam hit to PF03616, Glt_symporter, score 2.6e-239 663951011777 11 probable transmembrane helices predicted for SATW20_24760 by TMHMM2.0 at aa 5-27, 34-56, 66-88, 95-117,158-180, 219-236, 240-262, 282-304, 308-330, 339-361 and 376-398 663951011778 isopentenyl pyrophosphate isomerase; Provisional; Region: PRK05437 663951011779 Isopentenyl-diphosphate:dimethylallyl diphosphate isomerase type 2 (IDI-2) FMN-binding domain. Two types of IDIs have been characterized at present. The long known IDI-1 is only dependent on divalent metals for activity, whereas IDI-2 requires a metal; Region: IDI-2_FMN; cd02811 663951011780 homotetramer interface [polypeptide binding]; other site 663951011781 FMN binding site [chemical binding]; other site 663951011782 homodimer contacts [polypeptide binding]; other site 663951011783 putative active site [active] 663951011784 putative substrate binding site [chemical binding]; other site 663951011785 Predicted helix-turn-helix motif with score 1174.000, SD 3.19 at aa 271-292, sequence KSLALGAKATGMSRPFLNQVEN 663951011786 HMMPfam hit to PF01645, Glu_synthase, score 1.7e-05 663951011787 Mg2+ and Co2+ transporters [Inorganic ion transport and metabolism]; Region: CorA; COG0598 663951011788 Uncharacterized bacterial subfamily of the Thermotoga maritima CorA-like family; Region: TmCorA-like_u2; cd12831 663951011789 oligomer interface [polypeptide binding]; other site 663951011790 metal binding site [ion binding]; metal-binding site 663951011791 metal binding site [ion binding]; metal-binding site 663951011792 putative Cl binding site [ion binding]; other site 663951011793 aspartate ring; other site 663951011794 basic sphincter; other site 663951011795 hydrophobic gate; other site 663951011796 periplasmic entrance; other site 663951011797 HMMPfam hit to PF01544, CorA, score 2.2e-35 663951011798 2 probable transmembrane helices predicted for SATW20_24780 by TMHMM2.0 at aa 255-277 and 287-309 663951011799 4-hydroxybenzoyl-CoA thioesterase (4HBT). Catalyzes the final step in the 4-chlorobenzoate degradation pathway in which 4-chlorobenzoate is converted to 4-hydroxybenzoate in certain soil-dwelling bacteria. 4HBT forms a homotetramer with four active sites; Region: 4HBT; cd00586 663951011800 active site 663951011801 Esterase/lipase [Lipid metabolism]; Region: Aes; COG0657 663951011802 Protein of unknown function (DUF2424); Region: DUF2424; pfam10340 663951011803 HMMPfam hit to PF07859, Abhydrolase_3, score 3.2e-24 663951011804 4 probable transmembrane helices predicted for SATW20_24820 by TMHMM2.0 at aa 32-54, 105-127, 134-156 and 183-205 663951011805 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 663951011806 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 663951011807 drug resistance transporter, EmrB/QacA subfamily; Region: efflux_EmrB; TIGR00711 663951011808 putative substrate translocation pore; other site 663951011809 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 663951011810 15 probable transmembrane helices predicted for SATW20_24830 by TMHMM2.0 at aa 5-25, 141-163, 178-200,207-229, 234-256, 269-288, 293-315, 328-345, 360-377,398-420, 425-447, 454-473, 488-510, 531-548 and 599-621 663951011811 HMMPfam hit to PF07690, MFS_1, score 5.5e-61 663951011812 Multidrug resistance efflux pump [Defense mechanisms]; Region: EmrA; COG1566 663951011813 Biotinyl_lipoyl_domains are present in biotin-dependent carboxylases/decarboxylases, the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases, and the H-protein of the glycine cleavage system (GCS). These domains transport CO2, acyl; Region: Biotinyl_lipoyl_domains; cl11404 663951011814 HlyD family secretion protein; Region: HlyD_3; pfam13437 663951011815 lipoyl-biotinyl attachment site [posttranslational modification]; other site 663951011816 HMMPfam hit to PF00364, Biotin_lipoyl, score 0.00016 663951011817 1 probable transmembrane helix predicted for SATW20_24840 by TMHMM2.0 at aa 4-26 663951011818 HMMPfam hit to PF00440, TetR_N, score 1e-06 663951011819 Predicted helix-turn-helix motif with score 1145.000, SD 3.09 at aa 25-46, sequence ISTKMICAYCNINRSTFYDYYK 663951011820 drug resistance transporter, Bcr/CflA subfamily; Region: efflux_Bcr_CflA; TIGR00710 663951011821 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 663951011822 putative substrate translocation pore; other site 663951011823 11 probable transmembrane helices predicted for SATW20_24860 by TMHMM2.0 at aa 13-35, 50-69, 81-103,139-161, 168-186, 222-244, 257-279, 289-311, 313-335,350-367 and 374-393 663951011824 HMMPfam hit to PF07690, MFS_1, score 2.5e-51 663951011825 Predicted membrane protein [Function unknown]; Region: COG4640 663951011826 zinc-ribbon domain; Region: zinc_ribbon_2; pfam13240 663951011827 1 probable transmembrane helix predicted for SATW20_24870 by TMHMM2.0 at aa 51-70 663951011828 helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347 663951011829 Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090 663951011830 putative Zn2+ binding site [ion binding]; other site 663951011831 putative DNA binding site [nucleotide binding]; other site 663951011832 HMMPfam hit to PF01047, MarR, score 5.1e-07 663951011833 Predicted helix-turn-helix motif with score 1618.000, SD 4.70 at aa 52-73, sequence LTISEITQRQGVNKAAVSRRIK 663951011834 Uncharacterized conserved protein [Function unknown]; Region: COG1434 663951011835 YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259 663951011836 putative active site [active] 663951011837 6 probable transmembrane helices predicted for SATW20_24890 by TMHMM2.0 at aa 5-27, 29-46, 50-67, 88-110,115-137 and 298-320 663951011838 HMMPfam hit to PF02698, DUF218, score 2.9e-53 663951011839 Transposase DDE domain; Region: DDE_Tnp_1; pfam01609 663951011840 ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136 663951011841 ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255 663951011842 Walker A/P-loop; other site 663951011843 ATP binding site [chemical binding]; other site 663951011844 Q-loop/lid; other site 663951011845 ABC transporter signature motif; other site 663951011846 Walker B; other site 663951011847 D-loop; other site 663951011848 H-loop/switch region; other site 663951011849 HMMPfam hit to PF00005, ABC_tran, score 1.8e-53 663951011850 PS00017 ATP/GTP-binding site motif A (P-loop). 663951011851 MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704 663951011852 ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms]; Region: SalY; COG0577 663951011853 FtsX-like permease family; Region: FtsX; pfam02687 663951011854 HMMPfam hit to PF02687, FtsX, score 8e-23 663951011855 4 probable transmembrane helices predicted for SATW20_24920 by TMHMM2.0 at aa 13-35, 232-254, 274-296 and 316-338 663951011856 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745 663951011857 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 663951011858 active site 663951011859 phosphorylation site [posttranslational modification] 663951011860 intermolecular recognition site; other site 663951011861 dimerization interface [polypeptide binding]; other site 663951011862 Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383 663951011863 DNA binding site [nucleotide binding] 663951011864 HMMPfam hit to PF00072, Response_reg, score 3.4e-33 663951011865 HMMPfam hit to PF00486, Trans_reg_C, score 6.7e-24 663951011866 PS00230 Neuraxin and MAP1B proteins repeated region signature. 663951011867 Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642 663951011868 Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225 663951011869 dimerization interface [polypeptide binding]; other site 663951011870 Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082 663951011871 dimer interface [polypeptide binding]; other site 663951011872 phosphorylation site [posttranslational modification] 663951011873 Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075 663951011874 ATP binding site [chemical binding]; other site 663951011875 Mg2+ binding site [ion binding]; other site 663951011876 G-X-G motif; other site 663951011877 2 probable transmembrane helices predicted for SATW20_24940 by TMHMM2.0 at aa 10-32 and 165-187 663951011878 HMMPfam hit to PF00672, HAMP, score 2.5e-13 663951011879 HMMPfam hit to PF00512, HisKA, score 1.4e-09 663951011880 HMMPfam hit to PF02518, HATPase_c, score 8.2e-31 663951011881 Response regulator of the LytR/AlgR family [Transcription / Signal transduction mechanisms]; Region: LytT; COG3279 663951011882 LytTr DNA-binding domain; Region: LytTR; smart00850 663951011883 HMMPfam hit to PF04397, LytTR, score 5e-24 663951011884 Protein of unknown function (DUF3021); Region: DUF3021; pfam11457 663951011885 4 probable transmembrane helices predicted for SATW20_24960 by TMHMM2.0 at aa 7-26, 53-75, 87-109 and 113-135 663951011886 Malate:quinone oxidoreductase (Mqo); Region: Mqo; pfam06039 663951011887 malate:quinone-oxidoreductase; Region: mal_quin_oxido; TIGR01320 663951011888 HMMPfam hit to PF06039, Mqo, score 0 663951011889 L-lactate permease [Energy production and conversion]; Region: LldP; COG1620 663951011890 L-lactate permease; Region: Lactate_perm; cl00701 663951011891 13 probable transmembrane helices predicted for SATW20_24980 by TMHMM2.0 at aa 12-34, 38-60, 67-89,127-149, 156-178, 193-215, 228-245, 250-267, 295-317,349-371, 392-414, 429-448 and 512-529 663951011892 HMMPfam hit to PF02652, Lactate_perm, score 7.4e-195 663951011893 Putative glycosyl/glycerophosphate transferases involved in teichoic acid biosynthesis TagF/TagB/EpsJ/RodC [Cell envelope biogenesis, outer membrane]; Region: TagB; COG1887 663951011894 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 663951011895 N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301 663951011896 Acetyltransferases [General function prediction only]; Region: RimI; COG0456 663951011897 Coenzyme A binding pocket [chemical binding]; other site 663951011898 HMMPfam hit to PF00583, Acetyltransf_1, score 6.6e-20 663951011899 Medium chain reductase/dehydrogenase (MDR)/zinc-dependent alcohol dehydrogenase-like family; Region: MDR; cl16912 663951011900 putative quinone oxidoreductase, YhdH/YhfP family; Region: oxido_YhdH; TIGR02823 663951011901 NAD(P) binding site [chemical binding]; other site 663951011902 HMMPfam hit to PF08240, ADH_N, score 2.7e-16 663951011903 HMMPfam hit to PF00107, ADH_zinc_N, score 3e-10 663951011904 N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301 663951011905 Coenzyme A binding pocket [chemical binding]; other site 663951011906 HMMPfam hit to PF00583, Acetyltransf_1, score 1.6e-12 663951011907 Thioredoxin reductase [Posttranslational modification, protein turnover, chaperones]; Region: TrxB; COG0492 663951011908 NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500 663951011909 Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070 663951011910 HMMPfam hit to PF07992, Pyr_redox_2, score 3.3e-09 663951011911 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 663951011912 HMMPfam hit to PF00070, Pyr_redox, score 2.1e-12 663951011913 Protein of unknown function (DUF2871); Region: DUF2871; pfam11070 663951011914 4 probable transmembrane helices predicted for SATW20_25050 by TMHMM2.0 at aa 5-22, 37-56, 68-90 and 105-127 663951011915 Predicted membrane protein [Function unknown]; Region: COG1511 663951011916 YhgE/Pip N-terminal domain; Region: pip_yhgE_Nterm; TIGR03061 663951011917 YhgE/Pip C-terminal domain; Region: pip_yhgE_Cterm; TIGR03062 663951011918 6 probable transmembrane helices predicted for SATW20_25060 by TMHMM2.0 at aa 9-31, 236-258, 271-293,308-330, 335-352 and 391-413 663951011919 HMMPfam hit to PF01061, ABC2_membrane, score 0.011 663951011920 probable dihydroxyacetone kinase regulator; Region: DHAK_reg; TIGR02366 663951011921 Transcriptional regulator C-terminal region; Region: TetR_C_8; pfam14278 663951011922 HMMPfam hit to PF00440, TetR_N, score 2.5e-07 663951011923 Mg2+ and Co2+ transporters [Inorganic ion transport and metabolism]; Region: CorA; COG0598 663951011924 uncharacterized bacterial subfamily of the Escherichia coli CorA-Salmonella typhimurium ZntB family; Region: EcCorA_ZntB-like_u2; cd12827 663951011925 Cl binding site [ion binding]; other site 663951011926 oligomer interface [polypeptide binding]; other site 663951011927 HMMPfam hit to PF01544, CorA, score 6.1e-08 663951011928 2 probable transmembrane helices predicted for SATW20_25080 by TMHMM2.0 at aa 260-282 and 287-309 663951011929 PTS system, sucrose-specific IIBC component; Region: PTS-II-BC-sucr; TIGR01996 663951011930 PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212 663951011931 active site turn [active] 663951011932 phosphorylation site [posttranslational modification] 663951011933 Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263 663951011934 8 probable transmembrane helices predicted for SATW20_25090 by TMHMM2.0 at aa 112-134, 154-176, 183-205,264-286, 299-321, 347-369, 404-423 and 447-469 663951011935 HMMPfam hit to PF02378, PTS_EIIC, score 9.8e-77 663951011936 HMMPfam hit to PF00367, PTS_EIIB, score 5.4e-17 663951011937 PS01035 PTS EIIB domains cysteine phosphorylation site signature. 663951011938 Protein of unknown function (DUF1722); Region: DUF1722; pfam08349 663951011939 HMMPfam hit to PF08349, DUF1722, score 1.3e-43 663951011940 helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342 663951011941 Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165 663951011942 HMMPfam hit to PF00165, HTH_AraC, score 1e-07 663951011943 Predicted helix-turn-helix motif with score 1732.000, SD 5.09 at aa 164-185, sequence LSLKDIAMHCNISESYCSNLFV 663951011944 HMMPfam hit to PF00165, HTH_AraC, score 1.8e-07 663951011945 Uncharacterized stress protein (general stress protein 26) [General function prediction only]; Region: COG3871 663951011946 Pyridoxamine 5'-phosphate oxidase; Region: Pyridox_oxidase; pfam01243 663951011947 HMMPfam hit to PF01243, Pyridox_oxidase, score 6.7e-17 663951011948 1 probable transmembrane helix predicted for SATW20_25130 by TMHMM2.0 at aa 7-29 663951011949 Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301 663951011950 Sodium:dicarboxylate symporter family; Region: SDF; cl00573 663951011951 HMMPfam hit to PF00375, SDF, score 4.2e-162 663951011952 8 probable transmembrane helices predicted for SATW20_25140 by TMHMM2.0 at aa 9-31, 46-68, 81-103,159-176, 204-226, 231-253, 323-345 and 360-382 663951011953 PS00713 Sodium:dicarboxylate symporter family signature 1. 663951011954 Protein of unknown function (DUF3139); Region: DUF3139; pfam11337 663951011955 1 probable transmembrane helix predicted for SATW20_25150 by TMHMM2.0 at aa 7-26 663951011956 helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347 663951011957 MarR family; Region: MarR_2; pfam12802 663951011958 HMMPfam hit to PF01047, MarR, score 2.2e-20 663951011959 Molecular chaperone (small heat shock protein) [Posttranslational modification, protein turnover, chaperones]; Region: IbpA; COG0071 663951011960 alpha-crystallin domain (ACD) found in alpha-crystallin-type small heat shock proteins, and a similar domain found in p23 (a cochaperone for Hsp90) and in other p23-like proteins; Region: alpha-crystallin-Hsps_p23-like; cl00175 663951011961 HMMPfam hit to PF00011, HSP20, score 6e-15 663951011962 Nitrate/nitrite transporter [Inorganic ion transport and metabolism]; Region: NarK; COG2223 663951011963 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 663951011964 putative substrate translocation pore; other site 663951011965 12 probable transmembrane helices predicted for SATW20_25180 by TMHMM2.0 at aa 12-34, 44-63, 70-89, 99-121,134-156, 161-180, 205-227, 242-259, 266-288, 292-314,327-349 and 359-378 663951011966 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 663951011967 HMMPfam hit to PF07690, MFS_1, score 1.1e-48 663951011968 CDS contains a nonsense mutation (opal) after codon 212 663951011969 PS00142 Neutral zinc metallopeptidases, zinc-binding region signature. 663951011970 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 663951011971 Helix-Turn-Helix DNA binding domain of the transcription regulators TipAL, Mta, and SkgA; Region: HTH_TipAL-Mta; cd01106 663951011972 MerR HTH family regulatory protein; Region: MerR_1; pfam13411 663951011973 DNA binding residues [nucleotide binding] 663951011974 dimer interface [polypeptide binding]; other site 663951011975 TipAS antibiotic-recognition domain; Region: TipAS; pfam07739 663951011976 Predicted helix-turn-helix motif with score 1346.000, SD 3.77 at aa 5-26, sequence YTLKDIIEITGVTKRTLHYYDE 663951011977 HMMPfam hit to PF00376, MerR, score 8.9e-11 663951011978 HMMPfam hit to PF07739, TipAS, score 8.7e-44 663951011979 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197 663951011980 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 663951011981 active site 663951011982 phosphorylation site [posttranslational modification] 663951011983 intermolecular recognition site; other site 663951011984 dimerization interface [polypeptide binding]; other site 663951011985 C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170 663951011986 DNA binding residues [nucleotide binding] 663951011987 dimerization interface [polypeptide binding]; other site 663951011988 HMMPfam hit to PF00196, GerE, score 1.5e-25 663951011989 PS00622 Bacterial regulatory proteins, luxR family signature. 663951011990 Predicted helix-turn-helix motif with score 1054.000, SD 2.78 at aa 153-174, sequence YGNKEIAEKLFVSVKTVEAHKT 663951011991 HMMPfam hit to PF00072, Response_reg, score 5.2e-26 663951011992 Signal transduction histidine kinase [Signal transduction mechanisms]; Region: COG4585 663951011993 Histidine kinase; Region: HisKA_3; pfam07730 663951011994 Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075 663951011995 ATP binding site [chemical binding]; other site 663951011996 Mg2+ binding site [ion binding]; other site 663951011997 G-X-G motif; other site 663951011998 HMMPfam hit to PF02518, HATPase_c, score 3.8e-19 663951011999 HMMPfam hit to PF07730, HisKA_3, score 1.9e-17 663951012000 PS00430 TonB-dependent receptor proteins signature 1. 663951012001 FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203 663951012002 Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065 663951012003 Nitrate reductase gamma subunit; Region: Nitrate_red_gam; pfam02665 663951012004 HMMPfam hit to PF02665, Nitrate_red_gam, score 4.2e-77 663951012005 5 probable transmembrane helices predicted for SATW20_25240 by TMHMM2.0 at aa 4-26, 47-69, 84-106, 126-148 and 186-208 663951012006 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 663951012007 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 663951012008 Nitrate reductase delta subunit [Energy production and conversion]; Region: NarJ; COG2180 663951012009 HMMPfam hit to PF02613, Nitrate_red_del, score 3.7e-09 663951012010 Nitrate reductase beta subunit [Energy production and conversion]; Region: NarY; COG1140 663951012011 Nitrate reductase alpha subunit [Energy production and conversion]; Region: NarG; COG5013 663951012012 Respiratory nitrate reductase A (NarGHI), alpha chain (NarG) and related proteins. Under anaerobic conditions in the presence of nitrate, E. coli synthesizes the cytoplasmic membrane-bound quinol-nitrate oxidoreductase (NarGHI), which reduces nitrate to...; Region: MopB_Nitrate-R-NarG-like; cd02750 663951012013 [4Fe-4S] binding site [ion binding]; other site 663951012014 Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928 663951012015 Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928 663951012016 Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928 663951012017 Respiratory nitrate reductase A (NarGHI), alpha chain (NarG) and related proteins. Under anaerobic conditions in the presence of nitrate, E. coli synthesizes the cytoplasmic membrane-bound quinol-nitrate oxidoreductase (NarGHI), which reduces nitrate to...; Region: MopB_CT_Nitrate-R-NarG-like; cd02776 663951012018 molybdopterin cofactor binding site; other site 663951012019 HMMPfam hit to PF01568, Molydop_binding, score 5.2e-24 663951012020 PS00932 Prokaryotic molybdopterin oxidoreductases signature 3. 663951012021 PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 663951012022 HMMPfam hit to PF00384, Molybdopterin, score 1.2e-128 663951012023 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 663951012024 PS00551 Prokaryotic molybdopterin oxidoreductases signature 1. 663951012025 Uroporphyrin-III C-methyltransferase (S-Adenosyl-L-methionine:uroporphyrinogen III methyltransferase, SUMT); Region: SUMT; cd11642 663951012026 active site 663951012027 SAM binding site [chemical binding]; other site 663951012028 homodimer interface [polypeptide binding]; other site 663951012029 HMMPfam hit to PF00446, GnRH, score 0.08 663951012030 HMMPfam hit to PF00590, TP_methylase, score 9.8e-55 663951012031 PS00840 Uroporphyrin-III C-methyltransferase signature 2. 663951012032 Small subunit of nitrite reductase (NirD) family, Rieske domain; composed of proteins similar to the Bacillus subtilis small subunit of assimilatory nitrite reductase containing a Rieske domain. The Rieske domain is a [2Fe-2S] cluster binding domain...; Region: Rieske_NirD_small_Bacillus; cd03530 663951012033 [2Fe-2S] cluster binding site [ion binding]; other site 663951012034 HMMPfam hit to PF00355, Rieske, score 8.3e-18 663951012035 NAD(P)H-nitrite reductase [Energy production and conversion]; Region: NirB; COG1251 663951012036 NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500 663951012037 Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070 663951012038 BFD-like [2Fe-2S] binding domain; Region: Fer2_BFD; pfam04324 663951012039 BFD-like [2Fe-2S] binding domain; Region: Fer2_BFD; pfam04324 663951012040 Nitrite/Sulfite reductase ferredoxin-like half domain; Region: NIR_SIR_ferr; pfam03460 663951012041 HMMPfam hit to PF01077, NIR_SIR, score 3.8e-51 663951012042 PS00365 Nitrite and sulfite reductases iron-sulfur/siroheme-binding site. 663951012043 HMMPfam hit to PF03460, NIR_SIR_ferr, score 2.1e-18 663951012044 HMMPfam hit to PF04324, Fer2_BFD, score 7.1e-05 663951012045 HMMPfam hit to PF04324, Fer2_BFD, score 3e-25 663951012046 HMMPfam hit to PF07992, Pyr_redox_2, score 5.7e-45 663951012047 HMMPfam hit to PF00070, Pyr_redox, score 8e-30 663951012048 HMMPfam hit to PF00070, Pyr_redox, score 0.00037 663951012049 Sirohydrochlorin ferrochelatase [Inorganic ion transport and metabolism]; Region: COG2138 663951012050 Sirohydrochlorin cobalt chelatase (CbiX) and sirohydrochlorin iron chelatase (SirB), N-terminal domain. SirB catalyzes the ferro-chelation of sirohydrochlorin to siroheme, the prosthetic group of sulfite and nitrite reductases. CbiX is a cobaltochelatase; Region: CbiX_SirB_N; cd03416 663951012051 putative active site [active] 663951012052 Class II Chelatase: a family of ATP-independent monomeric or homodimeric enzymes that catalyze the insertion of metal into protoporphyrin rings. This family includes protoporphyrin IX ferrochelatase (HemH), sirohydrochlorin ferrochelatase (SirB) and the...; Region: Chelatase_Class_II; cl02784 663951012053 active site 663951012054 HMMPfam hit to PF01903, CbiX, score 1.2e-37 663951012055 Acetyltransferases [General function prediction only]; Region: RimI; COG0456 663951012056 N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301 663951012057 Coenzyme A binding pocket [chemical binding]; other site 663951012058 GNAT acetyltransferase 2; Region: GNAT_acetyltr_2; pfam13718 663951012059 HMMPfam hit to PF00583, Acetyltransf_1, score 4.6e-12 663951012060 Formate/nitrite family of transporters [Inorganic ion transport and metabolism]; Region: FocA; COG2116 663951012061 HMMPfam hit to PF01226, Form_Nir_trans, score 5.4e-18 663951012062 6 probable transmembrane helices predicted for SATW20_25330 by TMHMM2.0 at aa 38-60, 75-97, 117-139,165-187, 200-222 and 242-264 663951012063 PS00146 Beta-lactamase class-A active site. 663951012064 2 probable transmembrane helices predicted for SATW20_25340 by TMHMM2.0 at aa 5-24 and 34-56 663951012065 Putative hydrophobic ligand-binding SRPBCC domain of Micromonospora echinospora CalC, human Aha1, and related proteins; Region: SRPBCC_CalC_Aha1-like; cd07814 663951012066 putative hydrophobic ligand binding site [chemical binding]; other site 663951012067 HMMPfam hit to PF08327, AHSA1, score 1.1e-14 663951012068 ABC-type metal ion transport system, periplasmic component/surface adhesin [Inorganic ion transport and metabolism]; Region: LraI; COG0803 663951012069 Helical backbone metal receptor (TroA-like domain). These proteins have been shown to function in the ABC transport of ferric siderophores and metal ions such as Mn2+, Fe3+, Cu2+ and/or Zn2+. Their ligand binding site is formed in the interface between...; Region: TroA-like; cl00262 663951012070 intersubunit interface [polypeptide binding]; other site 663951012071 YodA lipocalin-like domain; Region: YodA; pfam09223 663951012072 HMMPfam hit to PF09223, YodA, score 9.3e-133 663951012073 HMMPfam hit to PF01297, SBP_bac_9, score 4e-61 663951012074 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 663951012075 Plasmid encoded toxin Txe; Region: Plasmid_Txe; pfam06769 663951012076 HMMPfam hit to PF06769, Plasmid_Txe, score 1.7e-32 663951012077 Antitoxin of toxin-antitoxin stability system [Cell division and chromosome partitioning]; Region: StbD; COG2161 663951012078 PS00017 ATP/GTP-binding site motif A (P-loop). 663951012079 HMMPfam hit to PF02604, PhdYeFM, score 6.8e-26 663951012080 Protein-disulfide isomerase [Posttranslational modification, protein turnover, chaperones]; Region: DsbG; COG1651 663951012081 Thioredoxin; Region: Thioredoxin_4; cl17273 663951012082 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 663951012083 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 663951012084 FemAB family; Region: FemAB; pfam02388 663951012085 HMMPfam hit to PF02388, FemAB, score 3e-222 663951012086 ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126 663951012087 ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262 663951012088 Walker A/P-loop; other site 663951012089 ATP binding site [chemical binding]; other site 663951012090 Q-loop/lid; other site 663951012091 ABC transporter signature motif; other site 663951012092 Walker B; other site 663951012093 D-loop; other site 663951012094 H-loop/switch region; other site 663951012095 HMMPfam hit to PF00005, ABC_tran, score 9.4e-71 663951012096 PS00211 ABC transporters family signature. 663951012097 PS00017 ATP/GTP-binding site motif A (P-loop). 663951012098 ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215 663951012099 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 663951012100 dimer interface [polypeptide binding]; other site 663951012101 conserved gate region; other site 663951012102 putative PBP binding loops; other site 663951012103 ABC-ATPase subunit interface; other site 663951012104 HMMPfam hit to PF00528, BPD_transp_1, score 4.3e-26 663951012105 4 probable transmembrane helices predicted for SATW20_25430 by TMHMM2.0 at aa 30-52, 65-87, 102-121 and 207-229 663951012106 PS00402 Binding-protein-dependent transport systems inner membrane comp. sign. 663951012107 Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497 663951012108 Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134 663951012109 substrate binding pocket [chemical binding]; other site 663951012110 membrane-bound complex binding site; other site 663951012111 hinge residues; other site 663951012112 HMMPfam hit to PF00497, SBP_bac_3, score 3.8e-89 663951012113 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 663951012114 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 663951012115 Major Facilitator Superfamily; Region: MFS_1; pfam07690 663951012116 putative substrate translocation pore; other site 663951012117 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 663951012118 14 probable transmembrane helices predicted for SATW20_25450 by TMHMM2.0 at aa 13-35, 45-67, 74-96,100-122, 134-156, 161-180, 192-214, 224-243, 264-286,301-320, 327-346, 351-373, 394-416 and 444-466 663951012119 HMMPfam hit to PF07690, MFS_1, score 2.1e-58 663951012120 Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067 663951012121 catalytic core [active] 663951012122 Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067 663951012123 HMMPfam hit to PF00300, PGAM, score 1.7e-42 663951012124 PS00175 Phosphoglycerate mutase family phosphohistidine signature. 663951012125 Predicted Co/Zn/Cd cation transporters [Inorganic ion transport and metabolism]; Region: MMT1; COG0053 663951012126 cation diffusion facilitator family transporter; Region: CDF; TIGR01297 663951012127 HMMPfam hit to PF01545, Cation_efflux, score 1.9e-92 663951012128 5 probable transmembrane helices predicted for SATW20_25470 by TMHMM2.0 at aa 13-35, 39-61, 82-101,116-135 and 174-196 663951012129 B domain; Region: B; pfam02216 663951012130 B domain; Region: B; pfam02216 663951012131 C3 binding domain 4 of IgG-bind protein SBI; Region: Sbi-IV; pfam11621 663951012132 HMMPfam hit to PF02216, B, score 2.4e-33 663951012133 HMMPfam hit to PF02216, B, score 1.5e-31 663951012134 Leukocidin/Hemolysin toxin family; Region: Leukocidin; pfam07968 663951012135 HMMPfam hit to PF07968, Leukocidin, score 1.4e-129 663951012136 Leukocidin/Hemolysin toxin family; Region: Leukocidin; pfam07968 663951012137 HMMPfam hit to PF07968, Leukocidin, score 2.4e-126 663951012138 Leukocidin/Hemolysin toxin family; Region: Leukocidin; cl08468 663951012139 HMMPfam hit to PF07968, Leukocidin, score 4.2e-133 663951012140 4 probable transmembrane helices predicted for SATW20_25520 by TMHMM2.0 at aa 9-31, 53-75, 82-104 and 124-146 663951012141 Pimeloyl-CoA synthetase [Coenzyme metabolism]; Region: BioW; COG1424 663951012142 HMMPfam hit to PF03744, BioW, score 5e-29 663951012143 7-keto-8-aminopelargonate synthetase and related enzymes [Coenzyme metabolism]; Region: BioF; COG0156 663951012144 pyridoxal phosphate-dependent acyltransferase, putative; Region: gly_Cac_T_rel; TIGR01825 663951012145 pyridoxal 5'-phosphate binding pocket [chemical binding]; other site 663951012146 catalytic residue [active] 663951012147 HMMPfam hit to PF00155, Aminotran_1_2, score 4e-26 663951012148 biotin synthase; Validated; Region: PRK06256 663951012149 Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335 663951012150 FeS/SAM binding site; other site 663951012151 Biotin and Thiamin Synthesis associated domain; Region: BATS; pfam06968 663951012152 HMMPfam hit to PF06968, BATS, score 3.4e-43 663951012153 HMMPfam hit to PF04055, Radical_SAM, score 1.4e-22 663951012154 Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610 663951012155 adenosylmethionine-8-amino-7-oxononanoate transaminase; Region: bioA; TIGR00508 663951012156 inhibitor-cofactor binding pocket; inhibition site 663951012157 pyridoxal 5'-phosphate binding site [chemical binding]; other site 663951012158 catalytic residue [active] 663951012159 HMMPfam hit to PF00202, Aminotran_3, score 3.4e-125 663951012160 PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 663951012161 Dethiobiotin synthetase [Coenzyme metabolism]; Region: BioD; COG0132 663951012162 AAA domain; Region: AAA_26; pfam13500 663951012163 ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; Region: ABCC_MsbA; cd03251 663951012164 ABC-type cobalt transport system, ATPase component [Inorganic ion transport and metabolism]; Region: CbiO; COG1122 663951012165 Walker A/P-loop; other site 663951012166 ATP binding site [chemical binding]; other site 663951012167 Q-loop/lid; other site 663951012168 ABC transporter signature motif; other site 663951012169 Walker B; other site 663951012170 D-loop; other site 663951012171 H-loop/switch region; other site 663951012172 HMMPfam hit to PF00005, ABC_tran, score 1.2e-61 663951012173 PS00211 ABC transporters family signature. 663951012174 PS00017 ATP/GTP-binding site motif A (P-loop). 663951012175 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 663951012176 5 probable transmembrane helices predicted for SATW20_25580 by TMHMM2.0 at aa 21-43, 58-80, 140-157,161-179 and 242-264 663951012177 HMMPfam hit to PF00664, ABC_membrane, score 8.2e-07 663951012178 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 663951012179 ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132 663951012180 ABC transporter transmembrane region; Region: ABC_membrane; pfam00664 663951012181 ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201 663951012182 Walker A/P-loop; other site 663951012183 ATP binding site [chemical binding]; other site 663951012184 Q-loop/lid; other site 663951012185 ABC transporter signature motif; other site 663951012186 Walker B; other site 663951012187 D-loop; other site 663951012188 H-loop/switch region; other site 663951012189 HMMPfam hit to PF00005, ABC_tran, score 9.9e-59 663951012190 PS00211 ABC transporters family signature. 663951012191 PS00017 ATP/GTP-binding site motif A (P-loop). 663951012192 HMMPfam hit to PF00664, ABC_membrane, score 9.4e-21 663951012193 5 probable transmembrane helices predicted for SATW20_25590 by TMHMM2.0 at aa 22-44, 59-81, 142-159,163-185 and 250-272 663951012194 Predicted membrane protein [Function unknown]; Region: COG2246 663951012195 GtrA-like protein; Region: GtrA; pfam04138 663951012196 HMMPfam hit to PF04138, GtrA, score 2e-40 663951012197 4 probable transmembrane helices predicted for SATW20_25600 by TMHMM2.0 at aa 13-35, 40-62, 75-97 and 102-124 663951012198 glycerate kinase; Region: TIGR00045 663951012199 HMMPfam hit to PF02595, Gly_kinase, score 9.8e-163 663951012200 Glutamyl-tRNAGlu reductase, dimerisation domain; Region: GlutR_dimer; pfam00745 663951012201 1 probable transmembrane helix predicted for SATW20_25620 by TMHMM2.0 at aa 70-92 663951012202 drug resistance transporter, Bcr/CflA subfamily; Region: efflux_Bcr_CflA; TIGR00710 663951012203 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 663951012204 putative substrate translocation pore; other site 663951012205 12 probable transmembrane helices predicted for SATW20_25630 by TMHMM2.0 at aa 13-35, 50-72, 81-100,105-127, 139-161, 165-187, 217-239, 254-276, 283-305,309-331, 343-365 and 375-394 663951012206 HMMPfam hit to PF07690, MFS_1, score 8.2e-41 663951012207 Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3708 663951012208 HMMPfam hit to PF06445, AraC_E_bind, score 9.2e-31 663951012209 Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4990 663951012210 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 663951012211 Predicted phosphohydrolases [General function prediction only]; Region: Icc; COG1409 663951012212 putative phosphoesterase; Region: acc_ester; TIGR03729 663951012213 HMMPfam hit to PF00149, Metallophos, score 5.1e-13 663951012214 Gamma-aminobutyrate permease and related permeases [Amino acid transport and metabolism]; Region: AnsP; COG1113 663951012215 Spore germination protein; Region: Spore_permease; cl17796 663951012216 HMMPfam hit to PF00324, AA_permease, score 1.5e-122 663951012217 12 probable transmembrane helices predicted for SATW20_25670 by TMHMM2.0 at aa 13-35, 45-67, 80-102,122-144, 149-171, 191-213, 234-256, 271-293, 328-350,360-382, 403-420 and 425-442 663951012218 NhaP-type Na+/H+ and K+/H+ antiporters [Inorganic ion transport and metabolism]; Region: NhaP; COG0025 663951012219 12 probable transmembrane helices predicted for SATW20_25680 by TMHMM2.0 at aa 4-21, 28-45, 55-72, 84-106,110-132, 152-174, 184-206, 230-252, 280-302, 309-331,366-388 and 401-423 663951012220 HMMPfam hit to PF00999, Na_H_Exchanger, score 6.3e-38 663951012221 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 663951012222 Amino acid transporters [Amino acid transport and metabolism]; Region: PotE; COG0531 663951012223 11 probable transmembrane helices predicted for SATW20_25690 by TMHMM2.0 at aa 58-80, 106-128, 138-160,172-194, 209-231, 252-274, 302-324, 345-367, 372-394,407-426 and 430-447 663951012224 PS00589 PTS HPR component serine phosphorylation site signature. 663951012225 PS00012 Phosphopantetheine attachment site. 663951012226 Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680 663951012227 Beta-lactamase; Region: Beta-lactamase; pfam00144 663951012228 4 probable transmembrane helices predicted for SATW20_25700 by TMHMM2.0 at aa 7-26, 389-411, 432-454 and 469-491 663951012229 HMMPfam hit to PF00144, Beta-lactamase, score 1.3e-78 663951012230 NAD dependent epimerase/dehydratase family; Region: Epimerase; pfam01370 663951012231 Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931 663951012232 NAD(P) binding site [chemical binding]; other site 663951012233 active site 663951012234 HMMPfam hit to PF01370, Epimerase, score 3.1e-10 663951012235 2-dehydropantoate 2-reductase; Reviewed; Region: PRK06522 663951012236 Ketopantoate reductase PanE/ApbA; Region: ApbA; pfam02558 663951012237 Ketopantoate reductase PanE/ApbA C terminal; Region: ApbA_C; pfam08546 663951012238 HMMPfam hit to PF08546, ApbA_C, score 5e-49 663951012239 HMMPfam hit to PF02558, ApbA, score 1.1e-52 663951012240 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 663951012241 putative substrate translocation pore; other site 663951012242 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 663951012243 14 probable transmembrane helices predicted for SATW20_25730 by TMHMM2.0 at aa 13-31, 46-68, 81-103,108-130, 137-159, 163-185, 206-224, 229-251, 271-293,308-325, 338-357, 361-383, 411-433 and 437-459 663951012244 HMMPfam hit to PF07690, MFS_1, score 1.6e-48 663951012245 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 663951012246 dimer interface [polypeptide binding]; other site 663951012247 conserved gate region; other site 663951012248 ABC-ATPase subunit interface; other site 663951012249 HMMPfam hit to PF00528, BPD_transp_1, score 1.7e-27 663951012250 5 probable transmembrane helices predicted for SATW20_25740 by TMHMM2.0 at aa 27-49, 56-78, 88-110,138-160 and 185-207 663951012251 Predicted helix-turn-helix motif with score 1171.000, SD 3.18 at aa 114-135, sequence ANIKDAGKGMGMTRNQVLRMIE 663951012252 Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein) [Cell envelope biogenesis, outer membrane]; Region: OpuBC; COG1732 663951012253 ABC-type proline/glycine betaine transport systems, periplasmic components [Amino acid transport and metabolism]; Region: ProX; cl17891 663951012254 HMMPfam hit to PF04069, OpuAC, score 5e-75 663951012255 1 probable transmembrane helix predicted for SATW20_25750 by TMHMM2.0 at aa 7-26 663951012256 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 663951012257 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 663951012258 dimer interface [polypeptide binding]; other site 663951012259 conserved gate region; other site 663951012260 putative PBP binding loops; other site 663951012261 ABC-ATPase subunit interface; other site 663951012262 HMMPfam hit to PF00528, BPD_transp_1, score 2.7e-25 663951012263 5 probable transmembrane helices predicted for SATW20_25760 by TMHMM2.0 at aa 20-42, 49-71, 81-100,144-166 and 176-198 663951012264 PS00402 Binding-protein-dependent transport systems inner membrane comp. sign. 663951012265 Predicted helix-turn-helix motif with score 984.000,SD 2.54 at aa 106-127, sequence SNIKEAGKSMGMTQFQLMKDVE 663951012266 ABC-type proline/glycine betaine transport systems, ATPase components [Amino acid transport and metabolism]; Region: OpuBA; COG1125 663951012267 ATP-binding cassette domain of the osmoprotectant transporter; Region: ABC_OpuCA_Osmoprotection; cd03295 663951012268 Walker A/P-loop; other site 663951012269 ATP binding site [chemical binding]; other site 663951012270 Q-loop/lid; other site 663951012271 ABC transporter signature motif; other site 663951012272 Walker B; other site 663951012273 D-loop; other site 663951012274 H-loop/switch region; other site 663951012275 This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in association with the ABC transporter OpuCA. OpuCA is the ATP binding component of a bacterial solute transporter that serves a protective role to cells growing...; Region: CBS_pair_ABC_OpuCA_assoc2; cd04583 663951012276 HMMPfam hit to PF00571, CBS, score 9.6e-26 663951012277 HMMPfam hit to PF00005, ABC_tran, score 5.2e-65 663951012278 PS00211 ABC transporters family signature. 663951012279 PS00017 ATP/GTP-binding site motif A (P-loop). 663951012280 Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4430 663951012281 Domain of unknown function (DU1801); Region: DUF1801; pfam08818 663951012282 Bacteriocin-protection, YdeI or OmpD-Associated; Region: OmdA; pfam13376 663951012283 HMMPfam hit to PF08818, DUF1801, score 3e-32 663951012284 amino acid transporter; Region: 2A0306; TIGR00909 663951012285 14 probable transmembrane helices predicted for SATW20_25790 by TMHMM2.0 at aa 12-34, 44-66, 87-109,134-156, 163-185, 200-222, 242-264, 298-320, 345-367,372-394, 407-429, 433-450, 463-484 and 499-521 663951012286 HMMPfam hit to PF00324, AA_permease, score 3.3e-08 663951012287 HMMPfam hit to PF00324, AA_permease, score 4.2e-08 663951012288 Carboxylesterase type B [Lipid metabolism]; Region: PnbA; COG2272 663951012289 Esterases and lipases (includes fungal lipases, cholinesterases, etc.) These enzymes act on carboxylic esters (EC: 3.1.1.-). The catalytic apparatus involves three residues (catalytic triad): a serine, a glutamate or aspartate and a histidine.These...; Region: Esterase_lipase; cd00312 663951012290 substrate binding pocket [chemical binding]; other site 663951012291 catalytic triad [active] 663951012292 HMMPfam hit to PF00135, COesterase, score 5.2e-39 663951012293 PS00941 Carboxylesterases type-B signature 2. 663951012294 PS00122 Carboxylesterases type-B serine active site. 663951012295 Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814 663951012296 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 663951012297 putative substrate translocation pore; other site 663951012298 10 probable transmembrane helices predicted for SATW20_25810 by TMHMM2.0 at aa 7-29, 39-60, 73-95, 100-122,129-151, 155-177, 214-236, 246-268, 281-303 and 364-383 663951012299 HMMPfam hit to PF07690, MFS_1, score 1.9e-57 663951012300 PS00215 Mitochondrial energy transfer proteins signature. 663951012301 ABC-type uncharacterized transport system, permease component [General function prediction only]; Region: COG0390 663951012302 HMMPfam hit to PF03649, UPF0014, score 1.1e-57 663951012303 6 probable transmembrane helices predicted for SATW20_25820 by TMHMM2.0 at aa 2-21, 31-53, 60-77, 87-109,189-211 and 216-238 663951012304 ABC-type uncharacterized transport system, ATPase component [General function prediction only]; Region: COG4619 663951012305 First domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain1; cd03225 663951012306 Walker A/P-loop; other site 663951012307 ATP binding site [chemical binding]; other site 663951012308 Q-loop/lid; other site 663951012309 ABC transporter signature motif; other site 663951012310 Walker B; other site 663951012311 D-loop; other site 663951012312 H-loop/switch region; other site 663951012313 HMMPfam hit to PF00005, ABC_tran, score 6.5e-45 663951012314 PS00211 ABC transporters family signature. 663951012315 PS00017 ATP/GTP-binding site motif A (P-loop). 663951012316 Cellulase M and related proteins [Carbohydrate transport and metabolism]; Region: FrvX; COG1363 663951012317 M42 Peptidase, Endoglucanases; Region: M42_Frv; cd05656 663951012318 oligomer interface [polypeptide binding]; other site 663951012319 active site 663951012320 metal binding site [ion binding]; metal-binding site 663951012321 HMMPfam hit to PF05343, Peptidase_M42, score 7.7e-181 663951012322 Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4115 663951012323 HMMPfam hit to PF05016, Plasmid_stabil, score 1.9e-07 663951012324 Antitoxin of toxin-antitoxin stability system [Cell division and chromosome partitioning]; Region: StbD; COG2161 663951012325 HMMPfam hit to PF02604, PhdYeFM, score 1.6e-18 663951012326 Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4808 663951012327 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 663951012328 HMMPfam hit to PF06998, DUF1307, score 1.5e-66 663951012329 Glutamate synthase domain 2 [Amino acid transport and metabolism]; Region: GltB; COG0069 663951012330 Glutamate synthase (GltS) FMN-binding domain. GltS is a complex iron-sulfur flavoprotein that catalyzes the reductive synthesis of L-glutamate from 2-oxoglutarate and L-glutamine via intramolecular channelling of ammonia, a reaction in the plant, yeast...; Region: GltS_FMN; cd02808 663951012331 active site 663951012332 FMN binding site [chemical binding]; other site 663951012333 substrate binding site [chemical binding]; other site 663951012334 3Fe-4S cluster binding site [ion binding]; other site 663951012335 HMMPfam hit to PF01645, Glu_synthase, score 2.9e-115 663951012336 1 probable transmembrane helix predicted for SATW20_25880 by TMHMM2.0 at aa 9-31 663951012337 6 probable transmembrane helices predicted for SATW20_25890 by TMHMM2.0 at aa 26-48, 63-85, 106-128,148-170, 182-204 and 231-248 663951012338 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 663951012339 Major Facilitator Superfamily; Region: MFS_1; pfam07690 663951012340 putative substrate translocation pore; other site 663951012341 12 probable transmembrane helices predicted for SATW20_25900 by TMHMM2.0 at aa 7-29, 39-61, 74-93, 98-120,132-154, 159-178, 214-236, 241-263, 283-305, 309-331,338-360 and 364-386 663951012342 HMMPfam hit to PF07690, MFS_1, score 6.5e-51 663951012343 ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppF; COG1124 663951012344 ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257 663951012345 Walker A/P-loop; other site 663951012346 ATP binding site [chemical binding]; other site 663951012347 Q-loop/lid; other site 663951012348 ABC transporter signature motif; other site 663951012349 Walker B; other site 663951012350 D-loop; other site 663951012351 H-loop/switch region; other site 663951012352 HMMPfam hit to PF00005, ABC_tran, score 1.9e-56 663951012353 PS00211 ABC transporters family signature. 663951012354 PS00017 ATP/GTP-binding site motif A (P-loop). 663951012355 ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257 663951012356 nickel import ATP-binding protein NikD; Region: nickel_nikD; TIGR02770 663951012357 Walker A/P-loop; other site 663951012358 ATP binding site [chemical binding]; other site 663951012359 Q-loop/lid; other site 663951012360 ABC transporter signature motif; other site 663951012361 Walker B; other site 663951012362 D-loop; other site 663951012363 H-loop/switch region; other site 663951012364 Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097 663951012365 HMMPfam hit to PF00005, ABC_tran, score 4.1e-48 663951012366 PS00211 ABC transporters family signature. 663951012367 PS00017 ATP/GTP-binding site motif A (P-loop). 663951012368 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppC; COG1173 663951012369 N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911 663951012370 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 663951012371 dimer interface [polypeptide binding]; other site 663951012372 conserved gate region; other site 663951012373 ABC-ATPase subunit interface; other site 663951012374 HMMPfam hit to PF00528, BPD_transp_1, score 4e-38 663951012375 5 probable transmembrane helices predicted for SATW20_25930 by TMHMM2.0 at aa 13-35, 79-101, 122-144,194-216 and 236-258 663951012376 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601 663951012377 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 663951012378 dimer interface [polypeptide binding]; other site 663951012379 conserved gate region; other site 663951012380 putative PBP binding loops; other site 663951012381 ABC-ATPase subunit interface; other site 663951012382 HMMPfam hit to PF00528, BPD_transp_1, score 3.3e-62 663951012383 6 probable transmembrane helices predicted for SATW20_25940 by TMHMM2.0 at aa 9-31, 107-126, 139-161,176-193, 234-256 and 276-298 663951012384 ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747 663951012385 The substrate-binding component of an ABC-type nickel import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA; cd08489 663951012386 substrate binding site [chemical binding]; other site 663951012387 HMMPfam hit to PF00496, SBP_bac_5, score 2.6e-76 663951012388 PS01040 Bacterial extracellular solute-binding proteins, family 5 signature. 663951012389 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 663951012390 Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4408 663951012391 Uncharacterized protein conserved in bacteria (DUF2338); Region: DUF2338; pfam10100 663951012392 Medium chain reductase/dehydrogenase (MDR)/zinc-dependent alcohol dehydrogenase-like family; Region: MDR; cl16912 663951012393 Diaminopimelate epimerase [Amino acid transport and metabolism]; Region: DapF; COG0253 663951012394 2-deoxy-D-gluconate 3-dehydrogenase; Region: kduD; TIGR01832 663951012395 classical (c) SDRs; Region: SDR_c; cd05233 663951012396 NAD(P) binding site [chemical binding]; other site 663951012397 active site 663951012398 PS00061 Short-chain dehydrogenases/reductases family signature. 663951012399 AbgT putative transporter family; Region: ABG_transport; pfam03806 663951012400 p-Aminobenzoyl-glutamate transporter family; Region: ydaH; TIGR00819 663951012401 HMMPfam hit to PF03806, ABG_transport, score 0 663951012402 12 probable transmembrane helices predicted for SATW20_26010 by TMHMM2.0 at aa 32-54, 85-104, 124-157,164-186, 210-232, 269-291, 306-328, 341-363, 388-407,414-433, 443-462 and 482-504 663951012403 PS00019 Actinin-type actin-binding domain signature 1. 663951012404 Uncharacterized conserved protein [Function unknown]; Region: COG2128 663951012405 Carboxymuconolactone decarboxylase family; Region: CMD; pfam02627 663951012406 HMMPfam hit to PF02627, CMD, score 4e-11 663951012407 Protein of unknown function (DUF1433); Region: DUF1433; pfam07252 663951012408 HMMPfam hit to PF07252, DUF1433, score 7.9e-76 663951012409 1 probable transmembrane helix predicted for SATW20_26030 by TMHMM2.0 at aa 5-27 663951012410 Protein of unknown function (DUF1433); Region: DUF1433; pfam07252 663951012411 HMMPfam hit to PF07252, DUF1433, score 1.1e-79 663951012412 1 probable transmembrane helix predicted for SATW20_26040 by TMHMM2.0 at aa 5-27 663951012413 Short-chain alcohol dehydrogenase of unknown specificity [General function prediction only]; Region: COG4221 663951012414 classical (c) SDRs; Region: SDR_c; cd05233 663951012415 NAD(P) binding site [chemical binding]; other site 663951012416 active site 663951012417 HMMPfam hit to PF00106, adh_short, score 6.7e-28 663951012418 Domain of unknown function (DUF1413); Region: DUF1413; pfam07205 663951012419 Protein of unknown function, DUF576; Region: DUF576; pfam04507 663951012420 HMMPfam hit to PF04507, DUF576, score 2.9e-179 663951012421 1 probable transmembrane helix predicted for SATW20_26080 by TMHMM2.0 at aa 7-26 663951012422 Protein of unknown function, DUF576; Region: DUF576; pfam04507 663951012423 HMMPfam hit to PF04507, DUF576, score 2.8e-158 663951012424 N-terminal putative catalytic domain of uncharacterized prokaryotic and archeal HKD family nucleases fused to a DEAD/DEAH box helicase domain; Region: PLDc_N_DEXD_b2; cd09204 663951012425 PLD-like domain; Region: PLDc_2; pfam13091 663951012426 putative homodimer interface [polypeptide binding]; other site 663951012427 putative active site [active] 663951012428 catalytic site [active] 663951012429 DNA or RNA helicases of superfamily II [Transcription / DNA replication, recombination, and repair]; Region: SSL2; COG1061 663951012430 DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046 663951012431 ATP binding site [chemical binding]; other site 663951012432 putative Mg++ binding site [ion binding]; other site 663951012433 Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079 663951012434 nucleotide binding region [chemical binding]; other site 663951012435 DNA or RNA helicases of superfamily II [Transcription / DNA replication, recombination, and repair]; Region: SSL2; COG1061 663951012436 ATP-binding site [chemical binding]; other site 663951012437 Domain of unknown function (DUF3427); Region: DUF3427; pfam11907 663951012438 HMMPfam hit to PF00271, Helicase_C, score 4.8e-18 663951012439 HMMPfam hit to PF04851, ResIII, score 1.3e-55 663951012440 The MutT pyrophosphohydrolase is a prototypical Nudix hydrolase that catalyzes the hydrolysis of nucleoside and deoxynucleoside triphosphates (NTPs and dNTPs) by substitution at a beta-phosphorus to yield a nucleotide monophosphate (NMP) and inorganic...; Region: MutT_pyrophosphohydrolase; cd03425 663951012441 active site 663951012442 8-oxo-dGMP binding site [chemical binding]; other site 663951012443 nudix motif; other site 663951012444 metal binding site [ion binding]; metal-binding site 663951012445 HMMPfam hit to PF00293, NUDIX, score 1.1e-19 663951012446 PS00893 mutT domain signature. 663951012447 Phosphomannomutase [Carbohydrate transport and metabolism]; Region: {ManB}; COG1109 663951012448 This CD includes PGM2 (phosphoglucomutase 2) and PGM2L1 (phosphoglucomutase 2-like 1). The mammalian PGM2 is thought to be a phosphopentomutase that catalyzes the conversion of the nucleoside breakdown products, ribose-1-phosphate and...; Region: PGM2; cd05799 663951012449 active site 663951012450 substrate binding site [chemical binding]; other site 663951012451 metal binding site [ion binding]; metal-binding site 663951012452 HMMPfam hit to PF02878, PGM_PMM_I, score 5.4e-57 663951012453 PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 663951012454 HMMPfam hit to PF02879, PGM_PMM_II, score 2.3e-05 663951012455 HMMPfam hit to PF02880, PGM_PMM_III, score 0.14 663951012456 HMMPfam hit to PF00408, PGM_PMM_IV, score 1.9e-07 663951012457 1 probable transmembrane helix predicted for SATW20_26130 by TMHMM2.0 at aa 7-29 663951012458 3 probable transmembrane helices predicted for SATW20_26140 by TMHMM2.0 at aa 5-24, 47-69 and 74-96 663951012459 H+ Antiporter protein; Region: 2A0121; TIGR00900 663951012460 8 probable transmembrane helices predicted for SATW20_26150 by TMHMM2.0 at aa 20-38, 48-70, 77-99,156-190, 219-241, 256-278, 290-312 and 365-387 663951012461 HMMPfam hit to PF07690, MFS_1, score 7.3e-22 663951012462 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 663951012463 CDS contains a nonsense mutation (amber) after codon 125, and a frameshift after codon 181. Similar to Staphylococcus aureus (strain NCTC 8325) surface protein G SasG UniProt:Q2G2B2 (EMBL:CP000253) (1627 aa) fasta scores: E()=0, 89.124% id in 1085 aa 663951012464 HMMPfam hit to PF00746, Gram_pos_anchor, score 3.5e-06 663951012465 HMMPfam hit to PF07501, G5, score 6e-30 663951012466 HMMPfam hit to PF07501, G5, score 3.2e-29 663951012467 HMMPfam hit to PF07501, G5, score 1e-28 663951012468 HMMPfam hit to PF07501, G5, score 1e-28 663951012469 HMMPfam hit to PF07501, G5, score 1.1e-25 663951012470 HMMPfam hit to PF04650, YSIRK_signal, score 5e-12 663951012471 staphylococcal accessory regulator family; Region: Staph_reg_Sar; TIGR01889 663951012472 helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347 663951012473 staphylococcal accessory regulator family; Region: Staph_reg_Sar; TIGR01889 663951012474 Transcriptional regulators [Transcription]; Region: MarR; COG1846 663951012475 staphylococcal accessory regulator family; Region: Staph_reg_Sar; TIGR01889 663951012476 HMMPfam hit to PF01047, MarR, score 2.1e-05 663951012477 Prokaryotic UGPase catalyses the synthesis of UDP-glucose; Region: UGPase_prokaryotic; cd02541 663951012478 dTDP-glucose pyrophosphorylase [Cell envelope biogenesis, outer membrane]; Region: RfbA; COG1209 663951012479 active site 663951012480 tetramer interface; other site 663951012481 Predicted helix-turn-helix motif with score 1082.000, SD 2.87 at aa 250-271, sequence GERYDVGEKLGFVKTTIEYALK 663951012482 HMMPfam hit to PF00483, NTP_transferase, score 4.9e-29 663951012483 C-terminus of bacterial fibrinogen-binding adhesin; Region: SdrG_C_C; pfam10425 663951012484 Fibronectin binding repeat; Region: Fn_bind; pfam02986 663951012485 Gram positive anchor; Region: Gram_pos_anchor; pfam00746 663951012486 HMMPfam hit to PF00746, Gram_pos_anchor, score 4.9e-09 663951012487 PS00343 Gram-positive cocci surface proteins 'anchoring' hexapeptide. 663951012488 HMMPfam hit to PF02986, Fn_bind, score 0.0056 663951012489 HMMPfam hit to PF02986, Fn_bind, score 0.78 663951012490 C-terminus of bacterial fibrinogen-binding adhesin; Region: SdrG_C_C; pfam10425 663951012491 Fibronectin binding repeat; Region: Fn_bind; pfam02986 663951012492 Gram positive anchor; Region: Gram_pos_anchor; pfam00746 663951012493 HMMPfam hit to PF00746, Gram_pos_anchor, score 1.8e-09 663951012494 PS00343 Gram-positive cocci surface proteins 'anchoring' hexapeptide. 663951012495 HMMPfam hit to PF02986, Fn_bind, score 0.0056 663951012496 GntP family permease; Region: GntP_permease; pfam02447 663951012497 fructuronate transporter; Provisional; Region: PRK10034; cl15264 663951012498 HMMPfam hit to PF02447, GntP_permease, score 4e-247 663951012499 12 probable transmembrane helices predicted for SATW20_26240 by TMHMM2.0 at aa 5-24, 29-51, 63-85, 105-127,140-159, 179-201, 232-254, 269-288, 309-331, 351-373,385-407 and 427-449 663951012500 gluconate kinase, FGGY type; Region: gntK_FGGY; TIGR01314 663951012501 Gluconate kinases; a subfamily of the FGGY family of carbohydrate kinases; Region: FGGY_GntK; cd07770 663951012502 N- and C-terminal domain interface [polypeptide binding]; other site 663951012503 active site 663951012504 catalytic site [active] 663951012505 metal binding site [ion binding]; metal-binding site 663951012506 carbohydrate binding site [chemical binding]; other site 663951012507 ATP binding site [chemical binding]; other site 663951012508 HMMPfam hit to PF02782, FGGY_C, score 6.9e-88 663951012509 PS00445 FGGY family of carbohydrate kinases signature 2. 663951012510 HMMPfam hit to PF00370, FGGY_N, score 9.6e-84 663951012511 Transcriptional regulators [Transcription]; Region: GntR; COG1802 663951012512 Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377 663951012513 DNA-binding site [nucleotide binding]; DNA binding site 663951012514 FCD domain; Region: FCD; pfam07729 663951012515 HMMPfam hit to PF07729, FCD, score 0.00026 663951012516 HMMPfam hit to PF00392, GntR, score 1.3e-14 663951012517 PS00043 Bacterial regulatory proteins, gntR family signature. 663951012518 Predicted helix-turn-helix motif with score 1508.000, SD 4.32 at aa 38-59, sequence LTENQMAKQFNVSRSPIRDAFK 663951012519 Helix-Turn-Helix DNA binding domain of the transcription regulators TipAL, Mta, and SkgA; Region: HTH_TipAL-Mta; cd01106 663951012520 Predicted transcriptional regulators [Transcription]; Region: SoxR; COG0789 663951012521 DNA binding residues [nucleotide binding] 663951012522 2 probable transmembrane helices predicted for SATW20_26270 by TMHMM2.0 at aa 141-163 and 168-187 663951012523 HMMPfam hit to PF00376, MerR, score 9.7e-10 663951012524 Predicted helix-turn-helix motif with score 1686.000, SD 4.93 at aa 4-25, sequence YSTGELAKLCNVTTRTIQYYDR 663951012525 Nucleotidyltransferase (NT) domain of RelA- and SpoT-like ppGpp synthetases and hydrolases; Region: NT_Rel-Spo_like; cd05399 663951012526 Guanosine polyphosphate pyrophosphohydrolases/synthetases [Signal transduction mechanisms / Transcription]; Region: SpoT; COG0317 663951012527 synthetase active site [active] 663951012528 NTP binding site [chemical binding]; other site 663951012529 metal binding site [ion binding]; metal-binding site 663951012530 HMMPfam hit to PF04607, RelA_SpoT, score 4.2e-45 663951012531 Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4876 663951012532 Predicted membrane protein [Function unknown]; Region: COG1289 663951012533 Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515 663951012534 7 probable transmembrane helices predicted for SATW20_26300 by TMHMM2.0 at aa 12-34, 61-83, 253-275,280-299, 312-334, 349-368 and 375-397 663951012535 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 663951012536 D-galactonate transporter; Region: 2A0114; TIGR00893 663951012537 putative substrate translocation pore; other site 663951012538 11 probable transmembrane helices predicted for SATW20_26310 by TMHMM2.0 at aa 7-25, 48-70, 83-105,140-162, 167-186, 227-249, 270-292, 297-319, 326-348,363-385 and 392-409 663951012539 HMMPfam hit to PF07690, MFS_1, score 5.4e-70 663951012540 Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586 663951012541 SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335 663951012542 5 probable transmembrane helices predicted for SATW20_26320 by TMHMM2.0 at aa 13-35, 50-72, 108-127,137-159 and 179-196 663951012543 HMMPfam hit to PF09335, SNARE_assoc, score 3.5e-13 663951012544 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 663951012545 Major Facilitator Superfamily; Region: MFS_1; pfam07690 663951012546 putative substrate translocation pore; other site 663951012547 12 probable transmembrane helices predicted for SATW20_26330 by TMHMM2.0 at aa 7-29, 39-61, 74-96, 101-120,133-155, 160-182, 205-227, 237-259, 272-291, 296-318,331-353 and 357-379 663951012548 HMMPfam hit to PF07690, MFS_1, score 3e-47 663951012549 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 663951012550 PS00290 Immunoglobulins and major histocompatibility complex proteins signature. 663951012551 helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347 663951012552 MarR family; Region: MarR; pfam01047 663951012553 HMMPfam hit to PF01047, MarR, score 6.2e-19 663951012554 Predicted helix-turn-helix motif with score 1295.000, SD 3.60 at aa 53-74, sequence VNNKFLSEMLNVSKPAITKSIK 663951012555 gallidermin-class lantibiotic protection ABC transporter, ATP-binding subunit; Region: galliderm_ABC; TIGR03740 663951012556 ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201 663951012557 Walker A/P-loop; other site 663951012558 ATP binding site [chemical binding]; other site 663951012559 Q-loop/lid; other site 663951012560 ABC transporter signature motif; other site 663951012561 Walker B; other site 663951012562 D-loop; other site 663951012563 H-loop/switch region; other site 663951012564 HMMPfam hit to PF00005, ABC_tran, score 1.4e-46 663951012565 PS00017 ATP/GTP-binding site motif A (P-loop). 663951012566 PS00211 ABC transporters family signature. 663951012567 ABC-2 family transporter protein; Region: ABC2_membrane_2; pfam12679 663951012568 ABC-2 family transporter protein; Region: ABC2_membrane_4; pfam12730 663951012569 6 probable transmembrane helices predicted for SATW20_26360 by TMHMM2.0 at aa 17-36, 56-78, 98-120,144-166, 173-195 and 229-251 663951012570 Uncharacterized protein conserved in bacteria [Carbohydrate transport and metabolism]; Region: Fbp; COG3855 663951012571 HMMPfam hit to PF06874, FBPase_2, score 0 663951012572 Uncharacterized membrane protein [Function unknown]; Region: COG3949 663951012573 10 probable transmembrane helices predicted for SATW20_26380 by TMHMM2.0 at aa 7-26, 36-58, 78-100,115-134, 139-161, 187-209, 221-243, 267-289, 302-324 and 328-345 663951012574 Predicted esterase [General function prediction only]; Region: COG0400 663951012575 putative hydrolase; Provisional; Region: PRK11460 663951012576 HMMPfam hit to PF02230, Abhydrolase_2, score 3.5e-06 663951012577 N-terminal domain of Sphingobium chlorophenolicum 2,6-dichloro-p-hydroquinone 1,2-dioxygenase (PcpA), and similar proteins; Region: PcpA_N_like; cd08346 663951012578 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903 663951012579 Zn binding site [ion binding]; other site 663951012580 C-terminal domain of Sphingobium chlorophenolicum 2,6-dichloro-p-hydroquinone 1,2-dioxygenase (PcpA), and similar proteins; Region: PcpA_C_like; cd08347 663951012581 Zn binding site [ion binding]; other site 663951012582 HMMPfam hit to PF00903, Glyoxalase, score 2.2e-13 663951012583 helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347 663951012584 MarR family; Region: MarR; pfam01047 663951012585 HMMPfam hit to PF01047, MarR, score 2.3e-20 663951012586 Predicted acetyltransferase [General function prediction only]; Region: COG2388 663951012587 HMMPfam hit to PF00583, Acetyltransf_1, score 9.4e-07 663951012588 Predicted ring-cleavage extradiol dioxygenase [General function prediction only]; Region: COG2514 663951012589 This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_12; cd07255 663951012590 putative metal binding site [ion binding]; other site 663951012591 This domain superfamily is found in a variety of structurally related metalloproteins, including the type I extradiol dioxygenases, glyoxalase I and a group of antibiotic resistance proteins; Region: Glo_EDI_BRP_like; cl14632 663951012592 HMMPfam hit to PF00903, Glyoxalase, score 5.2e-12 663951012593 PS00082 Extradiol ring-cleavage dioxygenases signature. 663951012594 NAD(P)H:FMN oxidoreductase family. This domain catalyzes the reduction of flavin, nitrocompound, quinones and azo compounds using NADH or NADPH as an electron donor. The enzyme is a homodimer, and each monomer binds a FMN as co-factor. This family...; Region: NfsB_like_nitroreductase; cd02149 663951012595 dimer interface [polypeptide binding]; other site 663951012596 FMN binding site [chemical binding]; other site 663951012597 HMMPfam hit to PF00881, Nitroreductase, score 9.9e-55 663951012598 D-lactate dehydrogenase; Provisional; Region: PRK12480 663951012599 D-Lactate dehydrogenase and D-2-Hydroxyisocaproic acid dehydrogenase (D-HicDH), NAD-binding and catalytic domains; Region: LDH; cd12186 663951012600 homodimer interface [polypeptide binding]; other site 663951012601 ligand binding site [chemical binding]; other site 663951012602 NAD binding site [chemical binding]; other site 663951012603 catalytic site [active] 663951012604 HMMPfam hit to PF00389, 2-Hacid_dh, score 1.3e-37 663951012605 HMMPfam hit to PF02826, 2-Hacid_dh_C, score 1.2e-64 663951012606 PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 663951012607 PS00670 D-isomer specific 2-hydroxyacid dehydrogenases signature 2. 663951012608 Predicted hydrolases of the HAD superfamily [General function prediction only]; Region: Cof; COG0561 663951012609 Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427 663951012610 active site 663951012611 motif I; other site 663951012612 motif II; other site 663951012613 Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cl17915 663951012614 HMMPfam hit to PF08282, Hydrolase_3, score 3.6e-57 663951012615 PS01229 Hypothetical cof family signature 2. 663951012616 ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201 663951012617 ABC-type cobalt transport system, ATPase component [Inorganic ion transport and metabolism]; Region: CbiO; COG1122 663951012618 Walker A/P-loop; other site 663951012619 ATP binding site [chemical binding]; other site 663951012620 Q-loop/lid; other site 663951012621 ABC transporter signature motif; other site 663951012622 Walker B; other site 663951012623 D-loop; other site 663951012624 H-loop/switch region; other site 663951012625 HMMPfam hit to PF00005, ABC_tran, score 9.3e-14 663951012626 PS00017 ATP/GTP-binding site motif A (P-loop). 663951012627 6 probable transmembrane helices predicted for SATW20_26480 by TMHMM2.0 at aa 13-35, 48-70, 97-119,124-146, 153-173 and 208-230 663951012628 Sortases are cysteine transpeptidases, found in gram-positive bacteria, that anchor surface proteins to peptidoglycans of the bacterial cell wall envelope. They do so by catalyzing a transpeptidation reaction in which the surface protein substrate is...; Region: Sortase; cd00004 663951012629 active site 663951012630 catalytic site [active] 663951012631 HMMPfam hit to PF04203, Sortase, score 2.3e-54 663951012632 1 probable transmembrane helix predicted for SATW20_26490 by TMHMM2.0 at aa 7-24 663951012633 Sortase and related acyltransferases [Cell envelope biogenesis, outer membrane]; Region: COG1247 663951012634 N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301 663951012635 Coenzyme A binding pocket [chemical binding]; other site 663951012636 HMMPfam hit to PF00583, Acetyltransf_1, score 2.8e-21 663951012637 Serine dehydratase alpha chain; Region: SDH_alpha; cl12120 663951012638 L-serine deaminase [Amino acid transport and metabolism]; Region: SdaA; COG1760 663951012639 HMMPfam hit to PF03313, SDH_alpha, score 1.8e-119 663951012640 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 663951012641 L-serine deaminase [Amino acid transport and metabolism]; Region: SdaA; COG1760 663951012642 Serine dehydratase beta chain; Region: SDH_beta; pfam03315 663951012643 HMMPfam hit to PF03315, SDH_beta, score 1.4e-36 663951012644 Phosphotransferase system, EIIC; Region: PTS_EIIC_2; pfam13303 663951012645 Phosphotransferase system, fructose-specific IIC component [Carbohydrate transport and metabolism]; Region: FruA; COG1299 663951012646 9 probable transmembrane helices predicted for SATW20_26530 by TMHMM2.0 at aa 4-21, 34-56, 76-98, 103-120,130-152, 173-195, 205-224, 256-278 and 303-325 663951012647 HMMPfam hit to PF02378, PTS_EIIC, score 7e-05 663951012648 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 663951012649 1 probable transmembrane helix predicted for SATW20_26540 by TMHMM2.0 at aa 15-37 663951012650 Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697 663951012651 EamA-like transporter family; Region: EamA; pfam00892 663951012652 EamA-like transporter family; Region: EamA; pfam00892 663951012653 10 probable transmembrane helices predicted for SATW20_26550 by TMHMM2.0 at aa 7-29, 39-58, 79-101,106-125, 132-154, 159-181, 186-208, 223-245, 258-277 and 282-299 663951012654 HMMPfam hit to PF00892, DUF6, score 2.7e-15 663951012655 HMMPfam hit to PF00892, DUF6, score 2.5e-20 663951012656 Esterase/lipase [Lipid metabolism]; Region: Aes; COG0657 663951012657 Protein of unknown function (DUF2424); Region: DUF2424; pfam10340 663951012658 HMMPfam hit to PF07859, Abhydrolase_3, score 9.9e-24 663951012659 TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947 663951012660 catalytic residues [active] 663951012661 PS00190 Cytochrome c family heme-binding site signature. 663951012662 4-hydroxybenzoyl-CoA thioesterase (4HBT). Catalyzes the final step in the 4-chlorobenzoate degradation pathway in which 4-chlorobenzoate is converted to 4-hydroxybenzoate in certain soil-dwelling bacteria. 4HBT forms a homotetramer with four active sites; Region: 4HBT; cd00586 663951012663 active site 663951012664 Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263 663951012665 PTS system, glucose-specific IIBC component; Region: PTS-II-BC-glcB; TIGR02002 663951012666 PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212 663951012667 active site turn [active] 663951012668 phosphorylation site [posttranslational modification] 663951012669 PTS_IIA, PTS system, glucose/sucrose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_glc; cd00210 663951012670 HPr interaction site; other site 663951012671 glycerol kinase (GK) interaction site [polypeptide binding]; other site 663951012672 active site 663951012673 phosphorylation site [posttranslational modification] 663951012674 HMMPfam hit to PF00358, PTS_EIIA_1, score 3.8e-66 663951012675 PS00371 PTS EIIA domains phosphorylation site signature 1. 663951012676 HMMPfam hit to PF00367, PTS_EIIB, score 7e-17 663951012677 PS01035 PTS EIIB domains cysteine phosphorylation site signature. 663951012678 9 probable transmembrane helices predicted for SATW20_26590 by TMHMM2.0 at aa 12-34, 78-100, 138-160,180-202, 223-245, 283-305, 338-360, 364-386 and 393-415 663951012679 HMMPfam hit to PF02378, PTS_EIIC, score 1.5e-119 663951012680 pyruvate oxidase; Provisional; Region: PRK08611 663951012681 Pyrimidine (PYR) binding domain of POX; Region: TPP_PYR_POX; cd07039 663951012682 PYR/PP interface [polypeptide binding]; other site 663951012683 tetramer interface [polypeptide binding]; other site 663951012684 dimer interface [polypeptide binding]; other site 663951012685 TPP binding site [chemical binding]; other site 663951012686 Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205 663951012687 Thiamine pyrophosphate (TPP) family, Pyruvate oxidase (POX) subfamily, TPP-binding module; composed of proteins similar to Lactobacillus plantarum POX, which plays a key role in controlling acetate production under aerobic conditions. POX decarboxylates...; Region: TPP_POX; cd02014 663951012688 TPP-binding site [chemical binding]; other site 663951012689 HMMPfam hit to PF02775, TPP_enzyme_C, score 1.2e-60 663951012690 PS00187 Thiamine pyrophosphate enzymes signature. 663951012691 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 663951012692 HMMPfam hit to PF00205, TPP_enzyme_M, score 6e-48 663951012693 HMMPfam hit to PF02776, TPP_enzyme_N, score 3.4e-44 663951012694 Putative effector of murein hydrolase [Cell envelope biogenesis, outer membrane]; Region: LrgB; COG1346 663951012695 HMMPfam hit to PF04172, LrgB, score 1.9e-97 663951012696 6 probable transmembrane helices predicted for SATW20_26610 by TMHMM2.0 at aa 4-21, 30-52, 62-79, 90-112,149-171 and 204-226 663951012697 Putative effector of murein hydrolase LrgA [General function prediction only]; Region: COG1380 663951012698 HMMPfam hit to PF03788, LrgA, score 1.6e-17 663951012699 3 probable transmembrane helices predicted for SATW20_26620 by TMHMM2.0 at aa 13-35, 45-67 and 74-96 663951012700 Transcriptional regulator [Transcription]; Region: LysR; COG0583 663951012701 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 663951012702 The C-terminal substrate binding domain of LysR-like transcriptional regulator CidR, contains the type 2 periplasmic binding fold; Region: PBP2_CidR; cd08438 663951012703 putative dimerization interface [polypeptide binding]; other site 663951012704 HMMPfam hit to PF03466, LysR_substrate, score 2.1e-44 663951012705 HMMPfam hit to PF00126, HTH_1, score 4e-19 663951012706 PS00044 Bacterial regulatory proteins, lysR family signature. 663951012707 Predicted helix-turn-helix motif with score 1179.000, SD 3.20 at aa 16-37, sequence GGMTNASKSLYIAQPTISKAIK 663951012708 Protein of unknown function (DUF1250); Region: DUF1250; pfam06855 663951012709 HMMPfam hit to PF06855, DUF1250, score 1e-29 663951012710 Surface antigen [General function prediction only]; Region: COG3942 663951012711 CHAP domain; Region: CHAP; pfam05257 663951012712 HMMPfam hit to PF05257, CHAP, score 6.1e-42 663951012713 Class II hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase (HMGR); Region: HMG-CoA_reductase_classII; cd00644 663951012714 homodimer interface [polypeptide binding]; other site 663951012715 catalytic residues [active] 663951012716 NAD binding site [chemical binding]; other site 663951012717 substrate binding pocket [chemical binding]; other site 663951012718 flexible flap; other site 663951012719 PS01192 Hydroxymethylglutaryl-coenzyme A reductases signature 3. 663951012720 PS00066 Hydroxymethylglutaryl-coenzyme A reductases signature 1. 663951012721 "initiating" condensing enzymes are a subclass of decarboxylating condensing enzymes, including beta-ketoacyl [ACP] synthase, type III and polyketide synthases, type III, which include chalcone synthase and related enzymes. They are...; Region: init_cond_enzymes; cd00827 663951012722 3-hydroxy-3-methylglutaryl CoA synthase, prokaryotic clade; Region: HMG-CoA-S_prok; TIGR01835 663951012723 dimer interface [polypeptide binding]; other site 663951012724 active site 663951012725 HMMPfam hit to PF01154, HMG_CoA_synt_N, score 2.2e-15 663951012726 HMMPfam hit to PF08540, HMG_CoA_synt_C, score 1.9e-11 663951012727 Methylated DNA-protein cysteine methyltransferase [DNA replication, recombination, and repair]; Region: Ada; COG0350 663951012728 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain; Region: Methyltransf_1N; pfam02870 663951012729 The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445 663951012730 DNA binding site [nucleotide binding] 663951012731 active site 663951012732 HMMPfam hit to PF01035, DNA_binding_1, score 1.1e-33 663951012733 PS00374 Methylated-DNA--protein-cysteine methyltransferase active site. 663951012734 HMMPfam hit to PF02870, Methyltransf_1N, score 8e-08 663951012735 The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009 663951012736 ATPases associated with a variety of cellular activities; Region: AAA; smart00382 663951012737 Walker A motif; other site 663951012738 ATP binding site [chemical binding]; other site 663951012739 Walker B motif; other site 663951012740 arginine finger; other site 663951012741 UvrB/uvrC motif; Region: UVR; pfam02151 663951012742 The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009 663951012743 Walker A motif; other site 663951012744 ATP binding site [chemical binding]; other site 663951012745 Walker B motif; other site 663951012746 arginine finger; other site 663951012747 C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086 663951012748 HMMPfam hit to PF00004, AAA, score 5.9e-18 663951012749 PS00017 ATP/GTP-binding site motif A (P-loop). 663951012750 HMMPfam hit to PF02151, UVR, score 0.00026 663951012751 HMMPfam hit to PF07724, AAA_2, score 4.3e-78 663951012752 PS00017 ATP/GTP-binding site motif A (P-loop). 663951012753 Virus attachment protein p12 family; Region: P12; pfam12669 663951012754 1 probable transmembrane helix predicted for SATW20_26710 by TMHMM2.0 at aa 4-22 663951012755 Fe2+ transport system protein B [Inorganic ion transport and metabolism]; Region: FeoB; COG0370 663951012756 Ferrous iron transport protein B (FeoB) family; Region: FeoB; cd01879 663951012757 G1 box; other site 663951012758 GTP/Mg2+ binding site [chemical binding]; other site 663951012759 Switch I region; other site 663951012760 G2 box; other site 663951012761 G3 box; other site 663951012762 Switch II region; other site 663951012763 G4 box; other site 663951012764 G5 box; other site 663951012765 Nucleoside recognition; Region: Gate; pfam07670 663951012766 Ferrous iron transport protein B C terminus; Region: FeoB_C; pfam07664 663951012767 Nucleoside recognition; Region: Gate; pfam07670 663951012768 9 probable transmembrane helices predicted for SATW20_26720 by TMHMM2.0 at aa 280-302, 342-364, 385-407,422-444, 451-473, 514-536, 543-565, 606-628 and 640-662 663951012769 HMMPfam hit to PF07670, Gate, score 1.2e-14 663951012770 HMMPfam hit to PF07664, FeoB_C, score 4.7e-21 663951012771 HMMPfam hit to PF07670, Gate, score 5.5e-21 663951012772 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 663951012773 HMMPfam hit to PF02421, FeoB_N, score 1.8e-49 663951012774 HMMPfam hit to PF01926, MMR_HSR1, score 1.1e-22 663951012775 PS00017 ATP/GTP-binding site motif A (P-loop). 663951012776 Fe2+ transport system protein A [Inorganic ion transport and metabolism]; Region: FeoA; COG1918 663951012777 HMMPfam hit to PF04023, FeoA, score 4.9e-17 663951012778 Predicted drug exporters of the RND superfamily [General function prediction only]; Region: COG2409 663951012779 Mn2+ and Fe2+ transporters of the NRAMP family [Inorganic ion transport and metabolism]; Region: MntH; cl15845 663951012780 12 probable transmembrane helices predicted for SATW20_26740 by TMHMM2.0 at aa 12-31, 173-195, 197-219,223-245, 269-291, 301-323, 347-369, 515-537, 542-561,571-593, 626-645 and 655-677 663951012781 HMMPfam hit to PF03176, MMPL, score 5.1e-06 663951012782 HMMPfam hit to PF03176, MMPL, score 7e-16 663951012783 PS00402 Binding-protein-dependent transport systems inner membrane comp. sign. 663951012784 Transcriptional regulator [Transcription]; Region: AcrR; COG1309 663951012785 HMMPfam hit to PF00440, TetR_N, score 0.00045 663951012786 1-pyrroline-5-carboxylate dehydrogenase; Provisional; Region: PRK03137 663951012787 Delta(1)-pyrroline-5-carboxylate dehydrogenase, RocA; Region: ALDH_PutA-P5CDH-RocA; cd07124 663951012788 Glutamate binding site [chemical binding]; other site 663951012789 homodimer interface [polypeptide binding]; other site 663951012790 NAD binding site [chemical binding]; other site 663951012791 catalytic residues [active] 663951012792 HMMPfam hit to PF00171, Aldedh, score 4.6e-193 663951012793 PS00070 Aldehyde dehydrogenases cysteine active site. 663951012794 PS00687 Aldehyde dehydrogenases glutamic acid active site. 663951012795 maltose O-acetyltransferase; Provisional; Region: PRK10092 663951012796 Maltose O-acetyltransferase (MAT) and Galactoside O-acetyltransferase (GAT): MAT and GAT catalyze the CoA-dependent acetylation of the 6-hydroxyl group of their respective sugar substrates. MAT acetylates maltose and glucose exclusively at the C6...; Region: LbH_MAT_GAT; cd03357 663951012797 active site 663951012798 substrate binding site [chemical binding]; other site 663951012799 trimer interface [polypeptide binding]; other site 663951012800 CoA binding site [chemical binding]; other site 663951012801 HMMPfam hit to PF00132, Hexapep, score 0.11 663951012802 HMMPfam hit to PF00132, Hexapep, score 75 663951012803 HMMPfam hit to PF00132, Hexapep, score 0.69 663951012804 HMMPfam hit to PF00132, Hexapep, score 12 663951012805 1 probable transmembrane helix predicted for SATW20_26780 by TMHMM2.0 at aa 4-21 663951012806 Cation transport ATPase [Inorganic ion transport and metabolism]; Region: ZntA; COG2217 663951012807 Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371 663951012808 metal-binding site [ion binding] 663951012809 Cation transport ATPase [Inorganic ion transport and metabolism]; Region: ZntA; COG2217 663951012810 Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371 663951012811 metal-binding site [ion binding] 663951012812 E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122 663951012813 Soluble P-type ATPase [General function prediction only]; Region: COG4087 663951012814 HMMPfam hit to PF00403, HMA, score 3.8e-13 663951012815 PS01047 Heavy-metal-associated domain. 663951012816 HMMPfam hit to PF00403, HMA, score 4.2e-17 663951012817 PS01047 Heavy-metal-associated domain. 663951012818 8 probable transmembrane helices predicted for SATW20_26790 by TMHMM2.0 at aa 158-180, 190-212, 219-241,256-274, 407-429, 444-466, 748-767 and 771-790 663951012819 HMMPfam hit to PF00122, E1-E2_ATPase, score 6.6e-107 663951012820 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 663951012821 HMMPfam hit to PF00702, Hydrolase, score 3.5e-38 663951012822 PS00154 E1-E2 ATPases phosphorylation site. 663951012823 Cation transport ATPase [Inorganic ion transport and metabolism]; Region: ZntA; COG2217 663951012824 Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371 663951012825 metal-binding site [ion binding] 663951012826 HMMPfam hit to PF00403, HMA, score 4.1e-14 663951012827 PS01047 Heavy-metal-associated domain. 663951012828 D-lactate dehydrogenase; Validated; Region: PRK08605 663951012829 D-Lactate dehydrogenase and D-2-Hydroxyisocaproic acid dehydrogenase (D-HicDH), NAD-binding and catalytic domains; Region: LDH; cd12186 663951012830 homodimer interface [polypeptide binding]; other site 663951012831 ligand binding site [chemical binding]; other site 663951012832 NAD binding site [chemical binding]; other site 663951012833 catalytic site [active] 663951012834 HMMPfam hit to PF00389, 2-Hacid_dh, score 3.5e-38 663951012835 HMMPfam hit to PF02826, 2-Hacid_dh_C, score 2.2e-62 663951012836 PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 663951012837 PS00670 D-isomer specific 2-hydroxyacid dehydrogenases signature 2. 663951012838 PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 663951012839 transaminase; Reviewed; Region: PRK08068 663951012840 Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609 663951012841 pyridoxal 5'-phosphate binding site [chemical binding]; other site 663951012842 homodimer interface [polypeptide binding]; other site 663951012843 catalytic residue [active] 663951012844 HMMPfam hit to PF00155, Aminotran_1_2, score 5.7e-68 663951012845 PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 663951012846 phytoene desaturase; Region: crtI_fam; TIGR02734 663951012847 NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450 663951012848 HMMPfam hit to PF01593, Amino_oxidase, score 4.3e-05 663951012849 HMMPfam hit to PF01593, Amino_oxidase, score 8.1e-13 663951012850 Trans-Isoprenyl Diphosphate Synthases, head-to-head; Region: Trans_IPPS_HH; cd00683 663951012851 active site lid residues [active] 663951012852 substrate binding pocket [chemical binding]; other site 663951012853 catalytic residues [active] 663951012854 substrate-Mg2+ binding site; other site 663951012855 aspartate-rich region 1; other site 663951012856 aspartate-rich region 2; other site 663951012857 HMMPfam hit to PF00494, SQS_PSY, score 2.3e-24 663951012858 PS01044 Squalene and phytoene synthases signature 1. 663951012859 Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463 663951012860 Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761 663951012861 active site 663951012862 4 probable transmembrane helices predicted for SATW20_26850 by TMHMM2.0 at aa 4-23, 164-186, 277-299 and 330-352 663951012863 HMMPfam hit to PF00535, Glycos_transf_2, score 3.3e-23 663951012864 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 663951012865 Phytoene dehydrogenase and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG1233 663951012866 NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450 663951012867 Adenylosuccinate lyase C-terminus; Region: ADSL_C; cl17237 663951012868 NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500 663951012869 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 663951012870 HMMPfam hit to PF01593, Amino_oxidase, score 1.5e-12 663951012871 1 probable transmembrane helix predicted for SATW20_26870 by TMHMM2.0 at aa 126-145 663951012872 Surface antigen [General function prediction only]; Region: COG3942 663951012873 CHAP domain; Region: CHAP; pfam05257 663951012874 HMMPfam hit to PF05257, CHAP, score 2.6e-46 663951012875 Predicted acyltransferases [Lipid metabolism]; Region: COG1835 663951012876 glucans biosynthesis protein; Provisional; Region: opgC; PRK03854 663951012877 yrhL-like subfamily of SGNH-hydrolases, a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely...; Region: SGNH_hydrolase_yrhL_like; cd01840 663951012878 catalytic triad [active] 663951012879 catalytic triad [active] 663951012880 oxyanion hole [active] 663951012881 11 probable transmembrane helices predicted for SATW20_26890 by TMHMM2.0 at aa 17-39, 44-66, 87-105,147-169, 176-198, 213-232, 239-261, 271-293, 313-330,334-356 and 377-399 663951012882 HMMPfam hit to PF01757, Acyl_transf_3, score 4.1e-61 663951012883 Lytic Transglycosylase (LT) and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL). LTs...; Region: LT_GEWL; cd00254 663951012884 N-acetyl-D-glucosamine binding site [chemical binding]; other site 663951012885 catalytic residue [active] 663951012886 HMMPfam hit to PF06737, Transglycosylas, score 8.2e-24 663951012887 Predicted membrane protein, putative toxin regulator [General function prediction only]; Region: PfoR; COG3641 663951012888 Phosphotransferase system, EIIC; Region: PTS_EIIC_2; pfam13303 663951012889 PS00636 Nt-dnaJ domain signature. 663951012890 10 probable transmembrane helices predicted for SATW20_26910 by TMHMM2.0 at aa 13-35, 50-72, 79-96,106-128, 135-157, 172-194, 199-221, 225-247, 259-281 and 309-331 663951012891 PS00962 Ribosomal protein S2 signature 1. 663951012892 Transcriptional regulator [Transcription]; Region: AcrR; COG1309 663951012893 Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440 663951012894 HMMPfam hit to PF00440, TetR_N, score 1e-05 663951012895 Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4224 663951012896 HMMPfam hit to PF05979, DUF896, score 2.7e-44 663951012897 This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_24; cd09012 663951012898 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903 663951012899 HMMPfam hit to PF00903, Glyoxalase, score 0.00025 663951012900 NmrA (a transcriptional regulator) and HSCARG (an NADPH sensor) like proteins, atypical (a) SDRs; Region: NmrA_like_SDR_a; cd05251 663951012901 NmrA-like family; Region: NmrA; pfam05368 663951012902 NADP binding site [chemical binding]; other site 663951012903 active site 663951012904 regulatory binding site [polypeptide binding]; other site 663951012905 HMMPfam hit to PF05368, NmrA, score 2.3e-26 663951012906 Uncharacterized protein conserved in bacteria (DUF2316); Region: DUF2316; pfam10078 663951012907 Transcriptional regulator [Transcription]; Region: AcrR; COG1309 663951012908 Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440 663951012909 HMMPfam hit to PF00440, TetR_N, score 8.5e-13 663951012910 PS01081 Bacterial regulatory proteins, tetR family signature. 663951012911 Predicted helix-turn-helix motif with score 1867.000, SD 5.55 at aa 28-49, sequence ISMNRIAKELGIGMGTLYRHFK 663951012912 3-ketoacyl-(acyl-carrier-protein) reductase; Provisional; Region: fabG; PRK12825 663951012913 Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931 663951012914 NAD(P) binding site [chemical binding]; other site 663951012915 active site 663951012916 HMMPfam hit to PF00106, adh_short, score 9e-18 663951012917 PS00061 Short-chain dehydrogenases/reductases family signature. 663951012918 Predicted metal-dependent hydrolase of the TIM-barrel fold [General function prediction only]; Region: COG2159 663951012919 HMMPfam hit to PF04909, Amidohydro_2, score 4.5e-54 663951012920 CDS contains a frameshift after codon 87. Similar to Staphylococcus aureus (strain MRSA252) uncharacterized hydrolase SAR2661 UniProt:Q6GDM0 (EMBL:BX571856) (276 aa) fasta scores: E()=4.7e-112, 100.000% id in 276 aa 663951012921 HMMPfam hit to PF00561, Abhydrolase_1, score 2.2e-05 663951012922 Putative GTPases (G3E family) [General function prediction only]; Region: COG0523 663951012923 CobW/HypB/UreG, nucleotide-binding domain; Region: cobW; pfam02492 663951012924 Cobalamin synthesis protein cobW C-terminal domain; Region: CobW_C; pfam07683 663951012925 HMMPfam hit to PF07683, CobW_C, score 1.2e-11 663951012926 HMMPfam hit to PF02492, cobW, score 3.9e-69 663951012927 PS00217 Sugar transport proteins signature 2. 663951012928 PS00017 ATP/GTP-binding site motif A (P-loop). 663951012929 Fe2+ transport system protein B [Inorganic ion transport and metabolism]; Region: FeoB; COG0370 663951012930 Nucleoside recognition; Region: Gate; pfam07670 663951012931 8 probable transmembrane helices predicted for SATW20_27040 by TMHMM2.0 at aa 84-106, 148-170, 229-251,255-274, 310-332, 342-364, 388-410 and 425-444 663951012932 HMMPfam hit to PF07670, Gate, score 9.9e-14 663951012933 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 663951012934 HMMPfam hit to PF07670, Gate, score 1.6e-16 663951012935 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 663951012936 Thioredoxin reductase [Posttranslational modification, protein turnover, chaperones]; Region: TrxB; COG0492 663951012937 Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox_3; pfam13738 663951012938 HMMPfam hit to PF01266, DAO, score 4.4e-05 663951012939 intgrative conjugative element ICE6013 663951012940 Transposase and inactivated derivatives, IS30 family [DNA replication, recombination, and repair]; Region: Tra8; COG2826 663951012941 Homeodomain-like domain; Region: HTH_32; pfam13565 663951012942 Integrase core domain; Region: rve; pfam00665 663951012943 HMMPfam hit to PF00665, rve, score 9.5e-26 663951012944 PS01043 Transposases, IS30 family, signature. 663951012945 Tn552 663951012946 Uncharacterized ATPase, putative transposase [General function prediction only]; Region: COG2842 663951012947 PS00017 ATP/GTP-binding site motif A (P-loop). 663951012948 Helix-turn-helix domain; Region: HTH_28; pfam13518 663951012949 Winged helix-turn helix; Region: HTH_29; pfam13551 663951012950 Integrase core domain; Region: rve; pfam00665 663951012951 Mu transposase, C-terminal; Region: Mu-transpos_C; pfam09299 663951012952 HMMPfam hit to PF09299, Mu-transpos_C, score 3.7e-27 663951012953 HMMPfam hit to PF00665, rve, score 3.4e-33 663951012954 Predicted helix-turn-helix motif with score 1319.000, SD 3.68 at aa 34-55, sequence QSLSSISKSKGIALSTLYRWNK 663951012955 Site-specific recombinases, DNA invertase Pin homologs [DNA replication, recombination, and repair]; Region: PinR; COG1961 663951012956 Serine Recombinase (SR) family, Resolvase and Invertase subfamily, catalytic domain; members contain a C-terminal DNA binding domain. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and...; Region: SR_ResInv; cd03768 663951012957 catalytic residues [active] 663951012958 catalytic nucleophile [active] 663951012959 Presynaptic Site I dimer interface [polypeptide binding]; other site 663951012960 Synaptic Antiparallel dimer interface [polypeptide binding]; other site 663951012961 Synaptic Flat tetramer interface [polypeptide binding]; other site 663951012962 Synaptic Site I dimer interface [polypeptide binding]; other site 663951012963 Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed...; Region: HTH_Hin_like; cd00569 663951012964 DNA-binding interface [nucleotide binding]; DNA binding site 663951012965 HMMPfam hit to PF02796, HTH_7, score 1.7e-20 663951012966 Predicted helix-turn-helix motif with score 1887.000, SD 5.61 at aa 161-182, sequence TPIKTIAEQWQVSRTTIYRYLN 663951012967 HMMPfam hit to PF00239, Resolvase, score 5e-67 663951012968 PS00398 Site-specific recombinases signature 2. 663951012969 PS00397 Site-specific recombinases active site. 663951012970 Predicted transcriptional regulator [Transcription]; Region: COG3682 663951012971 HMMPfam hit to PF03965, Pencillinase_R, score 8.3e-46 663951012972 Antirepressor regulating drug resistance, predicted signal transduction N-terminal membrane component [Transcription / Signal transduction mechanisms]; Region: MecR1; COG4219 663951012973 Beta-lactamase class D [Defense mechanisms]; Region: COG2602 663951012974 HMMPfam hit to PF00905, Transpeptidase, score 2.2e-64 663951012975 6 probable transmembrane helices predicted for SATW20_27110 by TMHMM2.0 at aa 4-26, 38-60, 105-127,171-191, 211-233 and 309-331 663951012976 HMMPfam hit to PF05569, Peptidase_M56, score 2e-53 663951012977 Prokaryotic membrane lipoprotein lipid attachment site; Region: LPAM_1; pfam08139 663951012978 beta-lactamase TEM; Provisional; Region: PRK15442 663951012979 Beta-lactamase enzyme family; Region: Beta-lactamase2; pfam13354 663951012980 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 663951012981 HMMPfam hit to PF00144, Beta-lactamase, score 2.3e-37 663951012982 PS00146 Beta-lactamase class-A active site. 663951012983 Predicted helix-turn-helix motif with score 1001.000, SD 2.60 at aa 103-124, sequence ASQIEKDTGYYISYPTIYRYIR 663951012984 Protein involved in sex pheromone biosynthesis [General function prediction only]; Region: CamS; COG4851 663951012985 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 663951012986 1 probable transmembrane helix predicted for SATW20_27140 by TMHMM2.0 at aa 5-23 663951012987 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase; Region: Glucosaminidase; pfam01832 663951012988 Surface antigen [General function prediction only]; Region: COG3942 663951012989 CHAP domain; Region: CHAP; pfam05257 663951012990 HMMPfam hit to PF05257, CHAP, score 3.5e-35 663951012991 PS00017 ATP/GTP-binding site motif A (P-loop). 663951012992 1 probable transmembrane helix predicted for SATW20_27150 by TMHMM2.0 at aa 26-48 663951012993 PS00017 ATP/GTP-binding site motif A (P-loop). 663951012994 ribonuclease E; Reviewed; Region: rne; PRK10811 663951012995 7 probable transmembrane helices predicted for SATW20_27160 by TMHMM2.0 at aa 5-27, 121-143, 155-177,283-305, 312-334, 349-369 and 382-399 663951012996 FtsK/SpoIIIE family; Region: FtsK_SpoIIIE; pfam01580 663951012997 DNA segregation ATPase FtsK/SpoIIIE and related proteins [Cell division and chromosome partitioning]; Region: FtsK; COG1674 663951012998 HMMPfam hit to PF01580, FtsK_SpoIIIE, score 3e-19 663951012999 PS00017 ATP/GTP-binding site motif A (P-loop). 663951013000 2 probable transmembrane helices predicted for SATW20_27170 by TMHMM2.0 at aa 20-42 and 65-87 663951013001 AAA-like domain; Region: AAA_10; pfam12846 663951013002 PS00017 ATP/GTP-binding site motif A (P-loop). 663951013003 TcpE family; Region: TcpE; pfam12648 663951013004 3 probable transmembrane helices predicted for SATW20_27190 by TMHMM2.0 at aa 35-54, 58-77 and 90-107 663951013005 2 probable transmembrane helices predicted for SATW20_27200 by TMHMM2.0 at aa 20-42 and 49-66 663951013006 Conjugative transposon protein TcpC; Region: TpcC; pfam12642 663951013007 1 probable transmembrane helix predicted for SATW20_27210 by TMHMM2.0 at aa 40-59 663951013008 Replication initiation factor; Region: Rep_trans; pfam02486 663951013009 HMMPfam hit to PF02486, Rep_trans, score 7.6e-30 663951013010 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 663951013011 Bacterial protein of unknown function (DUF961); Region: DUF961; pfam06125 663951013012 Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4495 663951013013 type VII secretion effector, SACOL2603 family; Region: T7SS_SACOL2603; TIGR04197 663951013014 Phosphotransferase enzyme family; Region: APH; pfam01636 663951013015 Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs)...; Region: APH_ChoK_like; cd05120 663951013016 active site 663951013017 ATP binding site [chemical binding]; other site 663951013018 Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs)...; Region: APH_ChoK_like; cl17270 663951013019 active site 663951013020 ATP binding site [chemical binding]; other site 663951013021 HMMPfam hit to PF01636, APH, score 5.8e-35 663951013022 dihydroorotate dehydrogenase 2; Reviewed; Region: PRK05286 663951013023 Dihydroorotate dehydrogenase (DHOD) class 2. DHOD catalyzes the oxidation of (S)-dihydroorotate to orotate. This is the fourth step and the only redox reaction in the de novo biosynthesis of UMP, the precursor of all pyrimidine nucleotides. DHOD requires...; Region: DHOD_2_like; cd04738 663951013024 quinone interaction residues [chemical binding]; other site 663951013025 active site 663951013026 catalytic residues [active] 663951013027 FMN binding site [chemical binding]; other site 663951013028 substrate binding site [chemical binding]; other site 663951013029 HMMPfam hit to PF01180, DHO_dh, score 1.4e-71 663951013030 PS00911 Dihydroorotate dehydrogenase signature 1. 663951013031 PS00912 Dihydroorotate dehydrogenase signature 2. 663951013032 1 probable transmembrane helix predicted for SATW20_27310 by TMHMM2.0 at aa 69-88 663951013033 Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1636 663951013034 HMMPfam hit to PF02677, DUF208, score 1.4e-37 663951013035 Escherichia coli PhnB and similar proteins; the E. coli phnB gene is found next to an operon involved in the cleavage of carbon-phosphorus bonds in unactivated alkylphosphonates; Region: PhnB_like; cd06588 663951013036 dimer interface [polypeptide binding]; other site 663951013037 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903 663951013038 HMMPfam hit to PF00903, Glyoxalase, score 0.00017 663951013039 Transcriptional regulator [Transcription]; Region: AcrR; COG1309 663951013040 Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440 663951013041 HMMPfam hit to PF00440, TetR_N, score 8.4e-05 663951013042 Predicted helix-turn-helix motif with score 1202.000, SD 3.28 at aa 30-51, sequence ITVQQIADLADVNRSTFYTHYY 663951013043 Predicted acyl esterases [General function prediction only]; Region: COG2936 663951013044 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain; Region: PepX_C; pfam08530 663951013045 HMMPfam hit to PF02129, Peptidase_S15, score 2.3e-34 663951013046 HMMPfam hit to PF08530, PepX_C, score 7.4e-66 663951013047 Aspartate alpha-decarboxylase or L-aspartate 1-decarboxylase, a pyruvoyl group-dependent decarboxylase in beta-alanine production; Region: Asp_decarbox; cd06919 663951013048 tetramerization interface [polypeptide binding]; other site 663951013049 active site 663951013050 HMMPfam hit to PF02261, Asp_decarbox, score 2.8e-71 663951013051 pantoate--beta-alanine ligase; Region: panC; TIGR00018 663951013052 Pantoate-beta-alanine ligase; Region: PanC; cd00560 663951013053 active site 663951013054 ATP-binding site [chemical binding]; other site 663951013055 pantoate-binding site; other site 663951013056 HXXH motif; other site 663951013057 HMMPfam hit to PF02569, Pantoate_ligase, score 6.6e-137 663951013058 Ketopantoate hydroxymethyltransferase (KPHMT) is the first enzyme in the pantothenate biosynthesis pathway. Ketopantoate hydroxymethyltransferase (KPHMT) catalyzes the first committed step in the biosynthesis of pantothenate (vitamin B5), which is a...; Region: KPHMT-like; cd06557 663951013059 oligomerization interface [polypeptide binding]; other site 663951013060 active site 663951013061 metal binding site [ion binding]; metal-binding site 663951013062 HMMPfam hit to PF02548, Pantoate_transf, score 1.6e-120 663951013063 2-dehydropantoate 2-reductase; Provisional; Region: PRK12921 663951013064 Ketopantoate reductase PanE/ApbA; Region: ApbA; pfam02558 663951013065 Ketopantoate reductase PanE/ApbA C terminal; Region: ApbA_C; pfam08546 663951013066 HMMPfam hit to PF02558, ApbA, score 1.1e-27 663951013067 HMMPfam hit to PF08546, ApbA_C, score 1.1e-46 663951013068 Alpha-acetolactate decarboxylase [Secondary metabolites biosynthesis, transport, and catabolism]; Region: AlsD; COG3527 663951013069 HMMPfam hit to PF03306, AAL_decarboxy, score 5e-76 663951013070 L-lactate dehydrogenase; Reviewed; Region: ldh; PRK00066 663951013071 L-2-hydroxyisocapronate dehydrogenases and some bacterial L-lactate dehydrogenases; Region: HicDH_like; cd05291 663951013072 tetramer (dimer of dimers) interface [polypeptide binding]; other site 663951013073 NAD binding site [chemical binding]; other site 663951013074 dimer interface [polypeptide binding]; other site 663951013075 substrate binding site [chemical binding]; other site 663951013076 HMMPfam hit to PF02866, Ldh_1_C, score 1.3e-57 663951013077 PS00064 L-lactate dehydrogenase active site. 663951013078 HMMPfam hit to PF00056, Ldh_1_N, score 1.4e-69 663951013079 amino acid transporter; Region: 2A0306; TIGR00909 663951013080 HMMPfam hit to PF00324, AA_permease, score 3.5e-21 663951013081 12 probable transmembrane helices predicted for SATW20_27420 by TMHMM2.0 at aa 33-55, 59-81, 93-115,155-174, 187-209, 229-246, 267-289, 309-331, 365-384,388-405, 422-444 and 449-466 663951013082 4-aminobutyrate aminotransferase; Provisional; Region: PRK08593 663951013083 Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610 663951013084 inhibitor-cofactor binding pocket; inhibition site 663951013085 pyridoxal 5'-phosphate binding site [chemical binding]; other site 663951013086 catalytic residue [active] 663951013087 HMMPfam hit to PF00202, Aminotran_3, score 1.6e-100 663951013088 4 probable transmembrane helices predicted for SATW20_27440 by TMHMM2.0 at aa 7-29, 52-74, 81-103 and 113-135 663951013089 fructose-1,6-bisphosphate aldolase; Reviewed; Region: PRK05377 663951013090 catalytic residue [active] 663951013091 HMMPfam hit to PF00274, Glycolytic, score 1e-06 663951013092 malate:quinone oxidoreductase; Reviewed; Region: PRK13339 663951013093 malate:quinone-oxidoreductase; Region: mal_quin_oxido; TIGR01320 663951013094 HMMPfam hit to PF06039, Mqo, score 0 663951013095 Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases [Lipid metabolism]; Region: Acs; COG0365 663951013096 Adenylate forming domain, Class I; Region: AFD_class_I; cl17068 663951013097 acyl-activating enzyme (AAE) consensus motif; other site 663951013098 AMP binding site [chemical binding]; other site 663951013099 active site 663951013100 CoA binding site [chemical binding]; other site 663951013101 HMMPfam hit to PF00501, AMP-binding, score 1.8e-110 663951013102 PS00455 Putative AMP-binding domain signature. 663951013103 PS00211 ABC transporters family signature. 663951013104 Uncharacterized enzyme involved in biosynthesis of extracellular polysaccharides [General function prediction only]; Region: COG2329 663951013105 HMMPfam hit to PF03992, ABM, score 1.6e-14 663951013106 Protein of unknown function (DUF1250); Region: DUF1250; pfam06855 663951013107 HMMPfam hit to PF06855, DUF1250, score 4.2e-32 663951013108 choline dehydrogenase; Validated; Region: PRK02106 663951013109 GMC oxidoreductase; Region: GMC_oxred_C; pfam05199 663951013110 PS00044 Bacterial regulatory proteins, lysR family signature. 663951013111 HMMPfam hit to PF05199, GMC_oxred_C, score 7.1e-57 663951013112 HMMPfam hit to PF00732, GMC_oxred_N, score 1.6e-99 663951013113 PS00624 GMC oxidoreductases signature 2. 663951013114 PS00623 GMC oxidoreductases signature 1. 663951013115 Bacillus subtilis NAD+-dependent betaine aldehyde dehydrogenase-like; Region: ALDH_BADH-GbsA; cd07119 663951013116 glycine betaine aldehyde dehydrogenase; Region: BADH; TIGR01804 663951013117 tetramerization interface [polypeptide binding]; other site 663951013118 NAD(P) binding site [chemical binding]; other site 663951013119 catalytic residues [active] 663951013120 HMMPfam hit to PF00171, Aldedh, score 9.5e-247 663951013121 PS00070 Aldehyde dehydrogenases cysteine active site. 663951013122 PS00687 Aldehyde dehydrogenases glutamic acid active site. 663951013123 Predicted transcriptional regulators [Transcription]; Region: COG1510 663951013124 Choline-glycine betaine transporter [Cell envelope biogenesis, outer membrane]; Region: BetT; COG1292 663951013125 HMMPfam hit to PF02028, BCCT, score 1.4e-104 663951013126 12 probable transmembrane helices predicted for SATW20_27530 by TMHMM2.0 at aa 12-29, 44-66, 87-109,140-162, 192-214, 229-248, 260-282, 321-343, 356-378,413-435, 448-470 and 483-505 663951013127 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 663951013128 PS01303 BCCT family of transporters signature. 663951013129 PS00339 Aminoacyl-transfer RNA synthetases class-II signature 2. 663951013130 4Fe-4S single cluster domain; Region: Fer4_12; pfam13353 663951013131 Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335 663951013132 FeS/SAM binding site; other site 663951013133 HMMPfam hit to PF04055, Radical_SAM, score 9.1e-07 663951013134 anaerobic ribonucleoside-triphosphate reductase; Region: NrdD; TIGR02487 663951013135 Class III ribonucleotide reductase; Region: RNR_III; cd01675 663951013136 effector binding site; other site 663951013137 active site 663951013138 Zn binding site [ion binding]; other site 663951013139 glycine loop; other site 663951013140 HMMPfam hit to PF01228, Gly_radical, score 2.4e-29 663951013141 PS00850 Glycine radical signature. 663951013142 H+/citrate symporter [Energy production and conversion]; Region: CitM; COG2851 663951013143 Citrate transporter; Region: CitMHS; pfam03600 663951013144 12 probable transmembrane helices predicted for SATW20_27560 by TMHMM2.0 at aa 5-24, 31-53, 63-80, 93-115,120-139, 144-166, 181-203, 257-290, 305-327, 340-362,398-420 and 432-454 663951013145 HMMPfam hit to PF03600, CitMHS, score 4.3e-124 663951013146 precorrin-2 dehydrogenase; Reviewed; Region: PRK06718 663951013147 Putative NAD(P)-binding; Region: NAD_binding_7; pfam13241 663951013148 Sulfite reductase, alpha subunit (flavoprotein) [Inorganic ion transport and metabolism]; Region: CysJ; COG0369 663951013149 Flavodoxin; Region: Flavodoxin_1; pfam00258 663951013150 Cytochrome p450- like alpha subunits of E. coli sulfite reductase (SiR) multimerize with beta subunits to catalyze the NADPH dependent reduction of sulfite to sulfide. Beta subunits have an Fe4S4 cluster and a siroheme, while the alpha subunits (cysJ...; Region: SiR; cd06199 663951013151 FAD binding pocket [chemical binding]; other site 663951013152 FAD binding motif [chemical binding]; other site 663951013153 catalytic residues [active] 663951013154 NAD binding pocket [chemical binding]; other site 663951013155 phosphate binding motif [ion binding]; other site 663951013156 beta-alpha-beta structure motif; other site 663951013157 HMMPfam hit to PF00175, NAD_binding_1, score 1.2e-28 663951013158 HMMPfam hit to PF00667, FAD_binding_1, score 2e-21 663951013159 HMMPfam hit to PF00258, Flavodoxin_1, score 3.3e-44 663951013160 Glutathione (GSH) peroxidase family; tetrameric selenoenzymes that catalyze the reduction of a variety of hydroperoxides including lipid peroxidases, using GSH as a specific electron donor substrate. GSH peroxidase contains one selenocysteine residue per...; Region: GSH_Peroxidase; cd00340 663951013161 catalytic residues [active] 663951013162 dimer interface [polypeptide binding]; other site 663951013163 HMMPfam hit to PF00255, GSHPx, score 2.2e-33 663951013164 FtsX-like permease family; Region: FtsX; pfam02687 663951013165 10 probable transmembrane helices predicted for SATW20_27600 by TMHMM2.0 at aa 21-43, 53-75, 113-135,155-177, 198-217, 232-254, 284-306, 538-560, 596-618 and 628-650 663951013166 HMMPfam hit to PF02687, FtsX, score 0.0023 663951013167 ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136 663951013168 ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255 663951013169 Walker A/P-loop; other site 663951013170 ATP binding site [chemical binding]; other site 663951013171 Q-loop/lid; other site 663951013172 ABC transporter signature motif; other site 663951013173 Walker B; other site 663951013174 D-loop; other site 663951013175 H-loop/switch region; other site 663951013176 HMMPfam hit to PF00005, ABC_tran, score 3.9e-59 663951013177 PS00211 ABC transporters family signature. 663951013178 PS00017 ATP/GTP-binding site motif A (P-loop). 663951013179 Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642 663951013180 Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075 663951013181 ATP binding site [chemical binding]; other site 663951013182 Mg2+ binding site [ion binding]; other site 663951013183 G-X-G motif; other site 663951013184 HMMPfam hit to PF02518, HATPase_c, score 8.3e-27 663951013185 2 probable transmembrane helices predicted for SATW20_27620 by TMHMM2.0 at aa 13-30 and 35-57 663951013186 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745 663951013187 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 663951013188 active site 663951013189 phosphorylation site [posttranslational modification] 663951013190 intermolecular recognition site; other site 663951013191 dimerization interface [polypeptide binding]; other site 663951013192 Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383 663951013193 DNA binding site [nucleotide binding] 663951013194 HMMPfam hit to PF00486, Trans_reg_C, score 1.2e-14 663951013195 HMMPfam hit to PF00072, Response_reg, score 2.3e-31 663951013196 1 probable transmembrane helix predicted for SATW20_27640 by TMHMM2.0 at aa 4-21 663951013197 Alkaline phosphatase [Inorganic ion transport and metabolism]; Region: PhoA; COG1785 663951013198 Alkaline phosphatase homologues; alkaline phosphatases are non-specific phosphomonoesterases that catalyze the hydrolysis reaction via a phosphoseryl intermediate to produce inorganic phosphate and the corresponding alcohol, optimally at high pH; Region: alkPPc; cd00016 663951013199 dimer interface [polypeptide binding]; other site 663951013200 active site 663951013201 Alkaline phosphatase homologues; alkaline phosphatases are non-specific phosphomonoesterases that catalyze the hydrolysis reaction via a phosphoseryl intermediate to produce inorganic phosphate and the corresponding alcohol, optimally at high pH; Region: alkPPc; cl15837 663951013202 HMMPfam hit to PF00245, Alk_phosphatase, score 6.6e-97 663951013203 PS00123 Alkaline phosphatase active site. 663951013204 PS00017 ATP/GTP-binding site motif A (P-loop). 663951013205 helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347 663951013206 MarR family; Region: MarR_2; pfam12802 663951013207 Predicted esterase [General function prediction only]; Region: COG0627 663951013208 S-formylglutathione hydrolase; Region: PLN02442 663951013209 HMMPfam hit to PF00756, Esterase, score 9.5e-06 663951013210 YSIRK type signal peptide; Region: YSIRK_signal; pfam04650 663951013211 C-terminus of bacterial fibrinogen-binding adhesin; Region: SdrG_C_C; pfam10425 663951013212 Gram positive anchor; Region: Gram_pos_anchor; pfam00746 663951013213 HMMPfam hit to PF00746, Gram_pos_anchor, score 1.6e-07 663951013214 PS00343 Gram-positive cocci surface proteins 'anchoring' hexapeptide. 663951013215 1 probable transmembrane helix predicted for SATW20_27680 by TMHMM2.0 at aa 21-43 663951013216 HMMPfam hit to PF04650, YSIRK_signal, score 1.2e-11 663951013217 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664 663951013218 effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038 663951013219 ligand binding site [chemical binding]; other site 663951013220 flexible hinge region; other site 663951013221 Crp-like helix-turn-helix domain; Region: HTH_Crp_2; pfam13545 663951013222 Predicted helix-turn-helix motif with score 1236.000, SD 3.40 at aa 186-207, sequence LTIQLMSDMAGISRETAGHIIH 663951013223 HMMPfam hit to PF00027, cNMP_binding, score 3.8e-09 663951013224 carbamate kinase; Reviewed; Region: PRK12686 663951013225 AAK_CK: Carbamate kinase (CK) catalyzes both the ATP-phosphorylation of carbamate and carbamoyl phosphate (CP) utilization with the production of ATP from ADP and CP. Both CK (this CD) and nonhomologous CP synthetase synthesize carbamoyl phosphate, an...; Region: AAK_CK; cd04235 663951013226 putative substrate binding site [chemical binding]; other site 663951013227 nucleotide binding site [chemical binding]; other site 663951013228 nucleotide binding site [chemical binding]; other site 663951013229 homodimer interface [polypeptide binding]; other site 663951013230 HMMPfam hit to PF00696, AA_kinase, score 2.4e-81 663951013231 arginine-ornithine antiporter; Region: arg_ornith_anti; TIGR03810 663951013232 14 probable transmembrane helices predicted for SATW20_27710 by TMHMM2.0 at aa 13-31, 38-60, 75-97, 99-121,126-145, 157-179, 209-228, 241-263, 278-300, 334-356,360-382, 399-416, 421-438 and 451-473 663951013233 HMMPfam hit to PF00324, AA_permease, score 6.5e-05 663951013234 ornithine carbamoyltransferase; Validated; Region: PRK02102 663951013235 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729 663951013236 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185 663951013237 HMMPfam hit to PF00185, OTCace, score 8.7e-77 663951013238 HMMPfam hit to PF02729, OTCace_N, score 8.6e-69 663951013239 PS00097 Aspartate and ornithine carbamoyltransferases signature. 663951013240 arginine deiminase; Provisional; Region: PRK01388 663951013241 HMMPfam hit to PF02274, Amidinotransf, score 7e-222 663951013242 Arginine repressor [Transcription]; Region: ArgR; COG1438 663951013243 Arginine repressor, DNA binding domain; Region: Arg_repressor; pfam01316 663951013244 Arginine repressor, C-terminal domain; Region: Arg_repressor_C; pfam02863 663951013245 HMMPfam hit to PF02863, Arg_repressor_C, score 6.1e-11 663951013246 Zinc metalloprotease (elastase) [Amino acid transport and metabolism]; Region: LasB; COG3227 663951013247 Fungalysin/Thermolysin Propeptide Motif; Region: FTP; pfam07504 663951013248 Peptidase propeptide and YPEB domain; Region: PepSY; pfam03413 663951013249 Peptidase M4 family includes thermolysin, protealysin, aureolysin and neutral protease; Region: M4_neutral_protease; cd09597 663951013250 active site 663951013251 Zn binding site [ion binding]; other site 663951013252 HMMPfam hit to PF02868, Peptidase_M4_C, score 1.5e-88 663951013253 HMMPfam hit to PF01447, Peptidase_M4, score 1.9e-68 663951013254 PS00142 Neutral zinc metallopeptidases, zinc-binding region signature. 663951013255 HMMPfam hit to PF03413, PepSY, score 0.002 663951013256 HMMPfam hit to PF07504, FTP, score 3.4e-13 663951013257 1 probable transmembrane helix predicted for SATW20_27760 by TMHMM2.0 at aa 7-29 663951013258 1 probable transmembrane helix predicted for SATW20_27770 by TMHMM2.0 at aa 4-26 663951013259 Transcriptional antiterminator [Transcription]; Region: BglG; COG3711 663951013260 HTH domain; Region: HTH_11; pfam08279 663951013261 PRD domain; Region: PRD; pfam00874 663951013262 PTS_IIB_bgl_like: the PTS (phosphotransferase system) IIB domain of a family of sensory systems composed of a membrane-bound sugar-sensor (similar to BglF) and a transcription antiterminator (similar to BglG) which regulate expression of genes involved...; Region: PTS_IIB_bgl_like; cd05568 663951013263 active site 663951013264 P-loop; other site 663951013265 phosphorylation site [posttranslational modification] 663951013266 PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211 663951013267 active site 663951013268 phosphorylation site [posttranslational modification] 663951013269 HMMPfam hit to PF08279, HTH_11, score 3.9e-15 663951013270 Predicted helix-turn-helix motif with score 1430.000, SD 4.06 at aa 20-41, sequence ISSNEIAEHVNVSNRTVRNDIH 663951013271 HMMPfam hit to PF00874, PRD, score 2.3e-17 663951013272 HMMPfam hit to PF00359, PTS_EIIA_2, score 0.00019 663951013273 PS00372 PTS EIIA domains phosphorylation site signature 2. 663951013274 putative PTS system transporter subunits IIBC; Provisional; Region: PRK11404 663951013275 PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569 663951013276 active site 663951013277 P-loop; other site 663951013278 phosphorylation site [posttranslational modification] 663951013279 Phosphotransferase system, fructose-specific IIC component [Carbohydrate transport and metabolism]; Region: FruA; COG1299 663951013280 PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211 663951013281 active site 663951013282 phosphorylation site [posttranslational modification] 663951013283 HMMPfam hit to PF02379, PTS_IIB_fruc, score 5.9e-54 663951013284 HMMPfam hit to PF02378, PTS_EIIC, score 3e-21 663951013285 8 probable transmembrane helices predicted for SATW20_27790 by TMHMM2.0 at aa 133-155, 175-197, 218-240,255-277, 298-317, 337-359, 398-417 and 437-459 663951013286 HMMPfam hit to PF00359, PTS_EIIA_2, score 7.3e-09 663951013287 PS00372 PTS EIIA domains phosphorylation site signature 2. 663951013288 Phosphomannose isomerase [Carbohydrate transport and metabolism]; Region: ManA; COG1482 663951013289 mannose-6-phosphate isomerase, class I; Region: manA; TIGR00218 663951013290 HMMPfam hit to PF01238, PMI_typeI, score 1.1e-70 663951013291 Predicted membrane protein [Function unknown]; Region: COG1511 663951013292 YhgE/Pip N-terminal domain; Region: pip_yhgE_Nterm; TIGR03061 663951013293 YhgE/Pip C-terminal domain; Region: pip_yhgE_Cterm; TIGR03062 663951013294 6 probable transmembrane helices predicted for SATW20_27810 by TMHMM2.0 at aa 21-43, 793-815, 836-858,868-890, 897-919 and 949-971 663951013295 HMMPfam hit to PF01061, ABC2_membrane, score 0.0038 663951013296 N-acetylmuramoyl-L-alanine amidase; Validated; Region: PRK08581 663951013297 Muramidase (flagellum-specific) [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FlgJ; COG1705 663951013298 CHAP domain; Region: CHAP; pfam05257 663951013299 HMMPfam hit to PF01832, Glucosaminidase, score 2.1e-34 663951013300 HMMPfam hit to PF05257, CHAP, score 8.5e-50 663951013301 Isochorismatase family; Region: Isochorismatase; pfam00857 663951013302 Cysteine hydrolases; This family contains amidohydrolases, like CSHase (N-carbamoylsarcosine amidohydrolase), involved in creatine metabolism and nicotinamidase, converting nicotinamide to nicotinic acid and ammonia in the pyridine nucleotide cycle. It...; Region: cysteine_hydrolases; cd00431 663951013303 catalytic triad [active] 663951013304 conserved cis-peptide bond; other site 663951013305 HMMPfam hit to PF00857, Isochorismatase, score 1.5e-15 663951013306 1 probable transmembrane helix predicted for SATW20_27840 by TMHMM2.0 at aa 599-618 663951013307 accessory Sec system glycosyltransferase GtfB; Region: TIGR02919 663951013308 Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013 663951013309 accessory Sec system glycosylation protein GtfA; Region: TIGR02918 663951013310 This family is most closely related to the GT1 family of glycosyltransferases and is named after gtfA in Streptococcus gordonii, where it plays a role in the O-linked glycosylation of GspB, a cell surface glycoprotein involved in platelet binding. In...; Region: GT1_gtfA_like; cd04949 663951013311 HMMPfam hit to PF00534, Glycos_transf_1, score 1.2e-19 663951013312 HMMPfam hit to PF09318, DUF1975, score 2.1e-153 663951013313 accessory Sec system translocase SecA2; Region: secA2; TIGR03714 663951013314 DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cl17251 663951013315 SecA preprotein cross-linking domain; Region: SecA_PP_bind; smart00958 663951013316 HMMPfam hit to PF07516, SecA_SW, score 2.4e-05 663951013317 HMMPfam hit to PF07517, SecA_DEAD, score 2.8e-158 663951013318 HMMPfam hit to PF01043, SecA_PP_bind, score 8.5e-52 663951013319 accessory Sec system protein Asp3; Region: acc_sec_asp3; TIGR03711 663951013320 accessory Sec system protein Asp2; Region: acc_sec_asp2; TIGR03712 663951013321 accessory Sec system protein Asp1; Region: acc_sec_asp1; TIGR03713 663951013322 Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013 663951013323 preprotein translocase subunit SecY; Reviewed; Region: secY; PRK12417 663951013324 SecY translocase; Region: SecY; pfam00344 663951013325 10 probable transmembrane helices predicted for SATW20_27910 by TMHMM2.0 at aa 17-39, 63-85, 105-123,133-151, 158-177, 187-209, 230-252, 280-302, 337-359 and 369-391 663951013326 HMMPfam hit to PF00344, SecY, score 2.9e-12 663951013327 KxYKxGKxW signal peptide; Region: KxYKxGKxW; TIGR03715 663951013328 legume lectins; Region: lectin_L-type; cd01951 663951013329 homotetramer interaction site [polypeptide binding]; other site 663951013330 carbohydrate binding site [chemical binding]; other site 663951013331 metal binding site [ion binding]; metal-binding site 663951013332 Putative Ig domain; Region: He_PIG; pfam05345 663951013333 HMMPfam hit to PF00746, Gram_pos_anchor, score 6.3e-08 663951013334 PS00343 Gram-positive cocci surface proteins 'anchoring' hexapeptide. 663951013335 HMMPfam hit to PF05345, He_PIG, score 4.4e-11 663951013336 HMMPfam hit to PF05345, He_PIG, score 6e-10 663951013337 Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family [General function prediction only]; Region: COG1853 663951013338 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 663951013339 PS00639 Eukaryotic thiol (cysteine) proteases histidine active site. 663951013340 Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family [General function prediction only]; Region: COG1853 663951013341 methionine sulfoxide reductase A; Provisional; Region: PRK05528 663951013342 HMMPfam hit to PF01625, PMSR, score 1.2e-29 663951013343 Histone acetyltransferase HPA2 and related acetyltransferases [Transcription / General function prediction only]; Region: WecD; COG0454 663951013344 N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301 663951013345 Coenzyme A binding pocket [chemical binding]; other site 663951013346 HMMPfam hit to PF00583, Acetyltransf_1, score 2.1e-17 663951013347 Capsular polysaccharide biosynthesis protein [Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: CapC; COG4464 663951013348 HMMPfam hit to PF02811, PHP, score 3.6e-31 663951013349 capsular exopolysaccharide family; Region: eps_fam; TIGR01007 663951013350 The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203 663951013351 Capsular polysaccharide biosynthesis protein [Cell envelope biogenesis, outer membrane]; Region: COG3944 663951013352 Chain length determinant protein; Region: Wzz; cl15801 663951013353 2 probable transmembrane helices predicted for SATW20_28020 by TMHMM2.0 at aa 20-39 and 169-191 663951013354 HMMPfam hit to PF02706, Wzz, score 2.3e-43 663951013355 Transcriptional regulator [Transcription]; Region: AcrR; COG1309 663951013356 Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440 663951013357 HMMPfam hit to PF00440, TetR_N, score 1.7e-16 663951013358 Predicted helix-turn-helix motif with score 1314.000, SD 3.66 at aa 21-42, sequence TTLDDIAKSVNIKKASLYYHFD 663951013359 poly-beta-1,6 N-acetyl-D-glucosamine synthase; Region: PgaC_IcaA; TIGR03937 663951013360 CESA_like is the cellulose synthase superfamily; Region: CESA_like; cd06423 663951013361 DXD motif; other site 663951013362 HMMPfam hit to PF00535, Glycos_transf_2, score 9.3e-37 663951013363 3 probable transmembrane helices predicted for SATW20_28040 by TMHMM2.0 at aa 285-307, 319-341 and 351-373 663951013364 intracellular adhesion protein D; Region: PIA_icaD; TIGR03932 663951013365 2 probable transmembrane helices predicted for SATW20_28050 by TMHMM2.0 at aa 24-46 and 71-93 663951013366 intercellular adhesin biosynthesis polysaccharide N-deacetylase; Region: PIA_icaB; TIGR03933 663951013367 HMMPfam hit to PF01522, Polysacc_deac_1, score 5.8e-41 663951013368 CDS contains a frameshift after codon 286 663951013369 10 probable transmembrane helices predicted for SATW20_28070 by TMHMM2.0 at aa 7-29, 44-66, 79-101,116-138, 145-167, 187-204, 211-233, 248-270, 277-294 and 309-331 663951013370 PS00284 Serpins signature. 663951013371 Gram-positive signal peptide, YSIRK family; Region: YSIRK_signal; TIGR01168 663951013372 Predicted acetyltransferases and hydrolases with the alpha/beta hydrolase fold [General function prediction only]; Region: LipA; COG1075 663951013373 PS00120 Lipases, serine active site. 663951013374 PS00017 ATP/GTP-binding site motif A (P-loop). 663951013375 1 probable transmembrane helix predicted for SATW20_28080 by TMHMM2.0 at aa 13-35 663951013376 HMMPfam hit to PF04650, YSIRK_signal, score 1e-12 663951013377 Phosphoribosyl-AMP cyclohydrolase [Amino acid transport and metabolism]; Region: HisI; COG0139 663951013378 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein; Reviewed; Region: PRK02759 663951013379 Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) MazG-like domain found in Escherichia coli phosphoribosyl-ATP pyrophosphohydrolase (HisIE or PRATP-PH) and its homologs; Region: NTP-PPase_HisIE_like; cd11534 663951013380 metal binding site [ion binding]; metal-binding site 663951013381 HMMPfam hit to PF01503, PRA-PH, score 1.9e-30 663951013382 HMMPfam hit to PF01502, PRA-CH, score 2.4e-43 663951013383 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 663951013384 The cyclase subunit of imidazoleglycerol phosphate synthase (HisF). Imidazole glycerol phosphate synthase (IGPS) catalyzes the fifth step of histidine biosynthesis, the formation of the imidazole ring. IGPS converts N1-(5'-phosphoribulosyl)...; Region: HisF; cd04731 663951013385 Histidine biosynthesis protein; Region: His_biosynth; pfam00977 663951013386 substrate binding site [chemical binding]; other site 663951013387 glutamase interaction surface [polypeptide binding]; other site 663951013388 HMMPfam hit to PF00977, His_biosynth, score 9.7e-117 663951013389 HisA. Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase catalyzes the fourth step in histidine biosynthesis, an isomerisation of the aminoaldose moiety of ProFAR to the aminoketose of PRFAR (N-(5'-phospho-D-1...; Region: HisA; cd04732 663951013390 phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; Region: TIGR00007 663951013391 catalytic residues [active] 663951013392 HMMPfam hit to PF00977, His_biosynth, score 2.5e-82 663951013393 PS00152 ATP synthase alpha and beta subunits signature. 663951013394 imidazole glycerol phosphate synthase subunit HisH; Provisional; Region: hisH; PRK13142 663951013395 Type 1 glutamine amidotransferase (GATase1) domain found in imidazole glycerol phosphate synthase (IGPS); Region: GATase1_IGP_Synthase; cd01748 663951013396 putative active site [active] 663951013397 oxyanion strand; other site 663951013398 catalytic triad [active] 663951013399 HMMPfam hit to PF00117, GATase, score 7.7e-24 663951013400 Imidazoleglycerol-phosphate dehydratase; Region: IGPD; cd07914 663951013401 putative active site pocket [active] 663951013402 4-fold oligomerization interface [polypeptide binding]; other site 663951013403 metal binding residues [ion binding]; metal-binding site 663951013404 3-fold/trimer interface [polypeptide binding]; other site 663951013405 HMMPfam hit to PF00475, IGPD, score 1.5e-67 663951013406 PS00955 Imidazoleglycerol-phosphate dehydratase signature 2. 663951013407 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase [Amino acid transport and metabolism]; Region: HisC; COG0079 663951013408 Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609 663951013409 pyridoxal 5'-phosphate binding site [chemical binding]; other site 663951013410 homodimer interface [polypeptide binding]; other site 663951013411 catalytic residue [active] 663951013412 HMMPfam hit to PF00155, Aminotran_1_2, score 2.2e-22 663951013413 PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 663951013414 Histidinol dehydrogenase [Amino acid transport and metabolism]; Region: HisD; COG0141 663951013415 Histidinol dehydrogenase, HisD, E.C 1.1.1.23. Histidinol dehydrogenase catalyzes the last two steps in the L-histidine biosynthesis pathway, which is conserved in bacteria, archaea, fungi, and plants. These last two steps are (i) the NAD-dependent...; Region: Histidinol_dh; cd06572 663951013416 NAD binding site [chemical binding]; other site 663951013417 dimerization interface [polypeptide binding]; other site 663951013418 product binding site; other site 663951013419 substrate binding site [chemical binding]; other site 663951013420 zinc binding site [ion binding]; other site 663951013421 catalytic residues [active] 663951013422 HMMPfam hit to PF00815, Histidinol_dh, score 1.9e-129 663951013423 ATP phosphoribosyltransferase catalytic subunit; Provisional; Region: hisG; PRK13584 663951013424 ATP phosphoribosyltransferase [Amino acid transport and metabolism]; Region: HisG; COG0040 663951013425 HMMPfam hit to PF01634, HisG, score 3.9e-48 663951013426 ATP phosphoribosyltransferase regulatory subunit; Provisional; Region: hisZ; PRK12294 663951013427 Histidyl-tRNA synthetase; Region: tRNA-synt_His; pfam13393 663951013428 Catalytic NodB homology domain of the carbohydrate esterase 4 superfamily; Region: CE4_SF; cl15692 663951013429 Putative catalytic NodB homology domain of PgaB, IcaB, and similar proteins which consist of a deformed (beta/alpha)8 barrel fold with 5- or 6-strands; Region: CE4_NodB_like_5s_6s; cd10918 663951013430 putative active site [active] 663951013431 HMMPfam hit to PF01522, Polysacc_deac_1, score 2.4e-06 663951013432 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 663951013433 Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302 663951013434 N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182 663951013435 PS00038 Myc-type, 'helix-loop-helix' dimerization domain signature. 663951013436 ABC-type cobalt transport system, permease component CbiQ and related transporters [Inorganic ion transport and metabolism]; Region: CbiQ; COG0619 663951013437 5 probable transmembrane helices predicted for SATW20_28200 by TMHMM2.0 at aa 21-38, 43-60, 67-86, 115-137 and 248-267 663951013438 HMMPfam hit to PF02361, CbiQ, score 1.2e-26 663951013439 PS00339 Aminoacyl-transfer RNA synthetases class-II signature 2. 663951013440 ABC-type cobalt transport system, ATPase component [Inorganic ion transport and metabolism]; Region: CbiO; COG1122 663951013441 First domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain1; cd03225 663951013442 Walker A/P-loop; other site 663951013443 ATP binding site [chemical binding]; other site 663951013444 Q-loop/lid; other site 663951013445 ABC transporter signature motif; other site 663951013446 Walker B; other site 663951013447 D-loop; other site 663951013448 H-loop/switch region; other site 663951013449 ATP-binding cassette cobalt transporter; Region: DUF3744; pfam12558 663951013450 ABC-type cobalt transport system, ATPase component [Inorganic ion transport and metabolism]; Region: CbiO; COG1122 663951013451 First domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain1; cd03225 663951013452 Walker A/P-loop; other site 663951013453 ATP binding site [chemical binding]; other site 663951013454 Q-loop/lid; other site 663951013455 ABC transporter signature motif; other site 663951013456 Walker B; other site 663951013457 D-loop; other site 663951013458 H-loop/switch region; other site 663951013459 HMMPfam hit to PF00005, ABC_tran, score 2.9e-46 663951013460 PS00211 ABC transporters family signature. 663951013461 PS00017 ATP/GTP-binding site motif A (P-loop). 663951013462 HMMPfam hit to PF00005, ABC_tran, score 1.6e-32 663951013463 PS00211 ABC transporters family signature. 663951013464 PS00017 ATP/GTP-binding site motif A (P-loop). 663951013465 hypothetical protein; Provisional; Region: PRK13661 663951013466 HMMPfam hit to PF07155, DUF1393, score 4e-134 663951013467 5 probable transmembrane helices predicted for SATW20_28220 by TMHMM2.0 at aa 10-29, 42-64, 79-101,114-136 and 146-168 663951013468 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 663951013469 Uncharacterized conserved protein [Function unknown]; Region: COG1912 663951013470 HMMPfam hit to PF01887, DUF62, score 3e-73 663951013471 Uncharacterized conserved protein [Function unknown]; Region: COG2353 663951013472 HMMPfam hit to PF04264, YceI, score 6.3e-71 663951013473 Gluconolactonase [Carbohydrate transport and metabolism]; Region: COG3386 663951013474 Strictosidine synthase; Region: Str_synth; pfam03088 663951013475 HMMPfam hit to PF08450, SGL, score 2.2e-21 663951013476 putative rhodanese-related sulfurtransferase; Provisional; Region: PRK00142 663951013477 Member of the Rhodanese Homology Domain superfamily. This CD includes Escherichia coli YceA, Bacillus subtilis YbfQ, and similar uncharacterized proteins; Region: RHOD_YceA; cd01518 663951013478 active site residue [active] 663951013479 Protein of unknown function (DUF3650); Region: DUF3650; pfam12368 663951013480 HMMPfam hit to PF00581, Rhodanese, score 2.8e-18 663951013481 Pyroglutamyl peptidase (PGP) type I, also known as pyrrolidone carboxyl peptidase (pcp) type I: Enzymes responsible for cleaving pyroglutamate (pGlu) from the N-terminal end of specialized proteins. The N-terminal pGlu protects these proteins from...; Region: Peptidase_C15; cd00501 663951013482 putative substrate binding pocket [chemical binding]; other site 663951013483 AC domain interface; other site 663951013484 catalytic triad [active] 663951013485 AB domain interface; other site 663951013486 interchain disulfide; other site 663951013487 HMMPfam hit to PF01470, Peptidase_C15, score 3.3e-144 663951013488 PS01333 Pyrrolidone-carboxylate peptidase glutamic acid active site. 663951013489 PS01334 Pyrrolidone-carboxylate peptidase cysteine active site. 663951013490 DinB superfamily; Region: DinB_2; pfam12867 663951013491 Collagen binding domain; Region: Collagen_bind; pfam05737 663951013492 Cna protein B-type domain; Region: Cna_B; pfam05738 663951013493 Repeat unit of collagen-binding protein domain B; Region: CollagenBindB; cd00222 663951013494 domain interaction interfaces [polypeptide binding]; other site 663951013495 Repeat unit of collagen-binding protein domain B; Region: CollagenBindB; cd00222 663951013496 domain interaction interfaces [polypeptide binding]; other site 663951013497 Repeat unit of collagen-binding protein domain B; Region: CollagenBindB; cd00222 663951013498 domain interaction interfaces [polypeptide binding]; other site 663951013499 1 probable transmembrane helix predicted for SATW20_28290 by TMHMM2.0 at aa 784-803 663951013500 HMMPfam hit to PF05738, Cna_B, score 7.2e-10 663951013501 HMMPfam hit to PF05738, Cna_B, score 3e-11 663951013502 HMMPfam hit to PF05738, Cna_B, score 3.1e-18 663951013503 HMMPfam hit to PF05737, Collagen_bind, score 1.6e-52 663951013504 Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Region: CitT; COG0471 663951013505 Anion permease ArsB/NhaD. These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life. A typical anion permease contains 8-13 transmembrane helices...; Region: ArsB_NhaD_permease; cd00625 663951013506 transmembrane helices; other site 663951013507 HMMPfam hit to PF00939, Na_sulph_symp, score 1.1e-208 663951013508 12 probable transmembrane helices predicted for SATW20_28300 by TMHMM2.0 at aa 7-24, 34-51, 56-73, 78-100,174-196, 216-238, 272-290, 294-313, 326-348, 358-380,392-414 and 443-465 663951013509 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 663951013510 Predicted permeases [General function prediction only]; Region: RarD; COG2962 663951013511 Multidrug resistance efflux transporter; Region: EmrE; pfam13536 663951013512 10 probable transmembrane helices predicted for SATW20_28310 by TMHMM2.0 at aa 7-29, 34-56, 77-99, 103-125,132-149, 154-172, 179-201, 216-235, 240-262 and 272-291 663951013513 HMMPfam hit to PF00892, DUF6, score 8.4e-08 663951013514 HMMPfam hit to PF00892, DUF6, score 2.4e-11 663951013515 hypothetical protein; Provisional; Region: PRK07758 663951013516 Nuclear transport factor 2 (NTF2-like) superfamily. This family includes members of the NTF2 family, Delta-5-3-ketosteroid isomerases, Scytalone Dehydratases, and the beta subunit of Ring hydroxylating dioxygenases. This family is a classic example of...; Region: NTF2_like; cl09109 663951013517 Predicted helix-turn-helix motif with score 1265.000, SD 3.50 at aa 28-49, sequence YTKSSLMEMHGVGPKAISILEQ 663951013518 High-affinity nickel permease [Inorganic ion transport and metabolism]; Region: HoxN; COG3376 663951013519 8 probable transmembrane helices predicted for SATW20_28330 by TMHMM2.0 at aa 21-43, 48-67, 91-113,133-155, 197-219, 229-251, 272-294 and 319-341 663951013520 HMMPfam hit to PF03824, NicO, score 1.7e-138 663951013521 Arylamine N-acetyltransferase [Secondary metabolites biosynthesis, transport, and catabolism]; Region: NhoA; COG2162 663951013522 HMMPfam hit to PF00797, Acetyltransf_2, score 1.2e-103 663951013523 Uncharacterized conserved protein [Function unknown]; Region: HdeD; COG3247 663951013524 6 probable transmembrane helices predicted for SATW20_28350 by TMHMM2.0 at aa 7-29, 33-55, 68-90, 94-116,123-140 and 144-166 663951013525 ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136 663951013526 ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255 663951013527 Walker A/P-loop; other site 663951013528 ATP binding site [chemical binding]; other site 663951013529 Q-loop/lid; other site 663951013530 ABC transporter signature motif; other site 663951013531 Walker B; other site 663951013532 D-loop; other site 663951013533 H-loop/switch region; other site 663951013534 HMMPfam hit to PF00005, ABC_tran, score 7e-57 663951013535 PS00017 ATP/GTP-binding site motif A (P-loop). 663951013536 FtsX-like permease family; Region: FtsX; pfam02687 663951013537 10 probable transmembrane helices predicted for SATW20_28370 by TMHMM2.0 at aa 21-38, 58-80, 109-131,153-175, 197-219, 229-251, 290-312, 506-528, 562-584 and 594-616 663951013538 HMMPfam hit to PF02687, FtsX, score 0.00012 663951013539 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 663951013540 Transposase and inactivated derivatives, IS30 family [DNA replication, recombination, and repair]; Region: Tra8; COG2826 663951013541 Integrase core domain; Region: rve; pfam00665 663951013542 Integrase core domain; Region: rve_3; cl15866 663951013543 Predicted helix-turn-helix motif with score 1477.000, SD 4.22 at aa 2-23, sequence LSVKEISSRLKRSRQTIYNVIN 663951013544 HMMPfam hit to PF00665, rve, score 6.9e-20 663951013545 PS00017 ATP/GTP-binding site motif A (P-loop). 663951013546 1 probable transmembrane helix predicted for SATW20_28400 by TMHMM2.0 at aa 5-27 663951013547 Peptidase domain in the S8 and S53 families; Region: Peptidases_S8_S53; cl10459 663951013548 active site 663951013549 catalytic residues [active] 663951013550 HMMPfam hit to PF00082, Peptidase_S8, score 1.4e-23 663951013551 1 probable transmembrane helix predicted for SATW20_28410 by TMHMM2.0 at aa 5-24 663951013552 Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea. CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458 663951013553 DNA-binding site [nucleotide binding]; DNA binding site 663951013554 RNA-binding motif; other site 663951013555 HMMPfam hit to PF00313, CSD, score 3.8e-40 663951013556 PS00352 'Cold-shock' DNA-binding domain signature. 663951013557 Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396 663951013558 Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093 663951013559 non-specific DNA binding site [nucleotide binding]; other site 663951013560 salt bridge; other site 663951013561 sequence-specific DNA binding site [nucleotide binding]; other site 663951013562 3 probable transmembrane helices predicted for SATW20_28430 by TMHMM2.0 at aa 80-102, 106-123 and 163-185 663951013563 HMMPfam hit to PF01381, HTH_3, score 1.8e-17 663951013564 Predicted helix-turn-helix motif with score 2265.000, SD 6.90 at aa 16-37, sequence YSQEYLAEKLYVSRQSISNWEN 663951013565 Protein of unknown function (DUF3147); Region: DUF3147; pfam11345 663951013566 4 probable transmembrane helices predicted for SATW20_28440 by TMHMM2.0 at aa 5-27, 31-53, 60-82 and 92-114 663951013567 Protein of unknown function (DUF3147); Region: DUF3147; pfam11345 663951013568 4 probable transmembrane helices predicted for SATW20_28450 by TMHMM2.0 at aa 4-25, 32-51, 66-88 and 95-114 663951013569 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 663951013570 Transposase IS200 like; Region: Y1_Tnp; pfam01797 663951013571 HMMPfam hit to PF01797, Transposase_17, score 8.4e-59 663951013572 nucleoid occlusion protein; Region: nucleoid_noc; TIGR04285 663951013573 ParB-like nuclease domain; Region: ParBc; pfam02195 663951013574 PS00017 ATP/GTP-binding site motif A (P-loop). 663951013575 Predicted helix-turn-helix motif with score 1898.000, SD 5.65 at aa 143-164, sequence TTQSELAKSLGKSQSFIANKLR 663951013576 HMMPfam hit to PF02195, ParBc, score 1.6e-34 663951013577 Predicted S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division [Cell envelope biogenesis, outer membrane]; Region: GidB; COG0357 663951013578 S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440 663951013579 S-adenosylmethionine binding site [chemical binding]; other site 663951013580 HMMPfam hit to PF02527, GidB, score 2.4e-78 663951013581 tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA; Validated; Region: PRK05192 663951013582 tRNA:m(5)U-54 methyltransferase; Region: gid_trmFO; TIGR00137 663951013583 GidA associated domain 3; Region: GIDA_assoc_3; pfam13932 663951013584 Predicted helix-turn-helix motif with score 1139.000, SD 3.07 at aa 592-613, sequence LNIAQASRISGVNPADISILLI 663951013585 HMMPfam hit to PF01134, GIDA, score 1.8e-270 663951013586 PS01281 Glucose inhibited division protein A family signature 2. 663951013587 tRNA modification GTPase TrmE; Reviewed; Region: trmE; PRK05291 663951013588 GTP-binding protein TrmE N-terminus; Region: TrmE_N; pfam10396 663951013589 trmE is a tRNA modification GTPase; Region: trmE; cd04164 663951013590 G1 box; other site 663951013591 GTP/Mg2+ binding site [chemical binding]; other site 663951013592 Switch I region; other site 663951013593 G2 box; other site 663951013594 Switch II region; other site 663951013595 G3 box; other site 663951013596 G4 box; other site 663951013597 G5 box; other site 663951013598 Catalytic cysteine-containing C-terminus of GTPase, MnmE; Region: GTPase_Cys_C; pfam12631 663951013599 HMMPfam hit to PF01926, MMR_HSR1, score 1.7e-39 663951013600 PS00017 ATP/GTP-binding site motif A (P-loop). 663951013601 ribonuclease P; Reviewed; Region: rnpA; PRK00499 663951013602 HMMPfam hit to PF00825, Ribonuclease_P, score 2.1e-29 663951013603 PS00648 Bacterial ribonuclease P protein component signature. 663951013604 50S ribosomal protein L34; Reviewed; Region: rpmH; PRK00399 663951013605 HMMPfam hit to PF00468, Ribosomal_L34, score 3.6e-20 663951013606 PS00784 Ribosomal protein L34 signature. 663951013607 Replication protein; Region: Rep_1; pfam01446 663951013608 alkylmercury lyase; Provisional; Region: PRK13239 663951013609 Helix-turn-helix domain of alkylmercury lyase; Region: HTH_15; pfam12324 663951013610 Alkylmercury lyase; Region: MerB; pfam03243 663951013611 HMMPfam hit to PF03243, MerB, score 3.6e-132 663951013612 Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3316 663951013613 Integrase core domain; Region: rve; pfam00665 663951013614 HMMPfam hit to PF00665, rve, score 3.2e-18 663951013615 Predicted helix-turn-helix motif with score 980.000, SD 2.52 at aa 31-52, sequence ISEILRERGVNVHHSTVYRWVQ 663951013616 4 probable transmembrane helices predicted for SATW20_p1050 by TMHMM2.0 at aa 9-31, 67-89, 102-124 and 129-146 663951013617 Probable gene remnant 663951013618 Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3316 663951013619 Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050 663951013620 Integrase core domain; Region: rve; pfam00665 663951013621 HMMPfam hit to PF00665, rve, score 8.2e-14 663951013622 Probable gene remnant 663951013623 HMMPfam hit to PF01446, Rep_1, score 4e-145 663951013624 Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090 663951013625 putative DNA binding site [nucleotide binding]; other site 663951013626 putative Zn2+ binding site [ion binding]; other site 663951013627 HMMPfam hit to PF01022, HTH_5, score 6.1e-17 663951013628 PS00846 Bacterial regulatory proteins, arsR family signature. 663951013629 potential frameshift: common BLAST hit: gi|270208727|ref|YP_003329494.1| CadD 663951013630 Cadmium resistance transporter; Region: Cad; pfam03596 663951013631 HMMPfam hit to PF03596, Cad, score 7.3e-22 663951013632 3 probable transmembrane helices predicted for SATW20_p1090 by TMHMM2.0 at aa 4-26, 33-55 and 70-88 663951013633 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 663951013634 Cadmium resistance transporter; Region: Cad; pfam03596 663951013635 3 probable transmembrane helices predicted for SATW20_p1100 by TMHMM2.0 at aa 5-27, 39-61 and 68-90 663951013636 HMMPfam hit to PF03596, Cad, score 6e-47 663951013637 Replication initiator protein A (RepA) N-terminus; Region: RepA_N; pfam06970 663951013638 HMMPfam hit to PF06970, RepA_N, score 2.3e-50 663951013639 Predicted helix-turn-helix motif with score 1386.000, SD 3.91 at aa 9-30, sequence KTIKMVADELNVTKQTIVNNAK 663951013640 HMMPfam hit to PF04394, DUF536, score 1.2e-13 663951013641 4 probable transmembrane helices predicted for SATW20_p1130 by TMHMM2.0 at aa 12-34, 39-56, 109-131 and 151-173 663951013642 Major Facilitator Superfamily; Region: MFS_1; pfam07690 663951013643 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 663951013644 putative substrate translocation pore; other site 663951013645 14 probable transmembrane helices predicted for SATW20_p1140 by TMHMM2.0 at aa 20-42, 57-79, 86-105, 110-132, 145-167, 173-195, 208-227, 238-255, 275-297, 312-334, 341-360, 370-392, 412-433 and 482-504 663951013646 HMMPfam hit to PF07690, MFS_1, score 1.6e-57 663951013647 PS00216 Sugar transport proteins signature 1. 663951013648 Transcriptional regulator [Transcription]; Region: AcrR; COG1309 663951013649 Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440 663951013650 QacR-like protein, C-terminal region; Region: TetR_C_5; pfam08360 663951013651 HMMPfam hit to PF00440, TetR_N, score 6.1e-19 663951013652 PS01081 Bacterial regulatory proteins, tetR family signature. 663951013653 HMMPfam hit to PF08360, TetR_C_5, score 6.8e-88 663951013654 3 probable transmembrane helices predicted for SATW20_p1160 by TMHMM2.0 at aa 4-26, 46-65 and 80-102 663951013655 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 663951013656 multiple promoter invertase; Provisional; Region: mpi; PRK13413 663951013657 Serine Recombinase (SR) family, Resolvase and Invertase subfamily, catalytic domain; members contain a C-terminal DNA binding domain. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and...; Region: SR_ResInv; cd03768 663951013658 catalytic residues [active] 663951013659 catalytic nucleophile [active] 663951013660 Presynaptic Site I dimer interface [polypeptide binding]; other site 663951013661 Synaptic Antiparallel dimer interface [polypeptide binding]; other site 663951013662 Synaptic Flat tetramer interface [polypeptide binding]; other site 663951013663 Synaptic Site I dimer interface [polypeptide binding]; other site 663951013664 DNA binding site [nucleotide binding] 663951013665 Helix-turn-helix domain of resolvase; Region: HTH_7; pfam02796 663951013666 DNA-binding interface [nucleotide binding]; DNA binding site 663951013667 HMMPfam hit to PF02796, HTH_7, score 2.1e-17 663951013668 Predicted helix-turn-helix motif with score 1839.000, SD 5.45 at aa 176-197, sequence KAISKIAKEVNITRQTVYRIKH 663951013669 HMMPfam hit to PF00239, Resolvase, score 1e-49 663951013670 PS00398 Site-specific recombinases signature 2. 663951013671 PS00397 Site-specific recombinases active site. 663951013672 Uncharacterized ATPase, putative transposase [General function prediction only]; Region: COG2842 663951013673 PS00017 ATP/GTP-binding site motif A (P-loop). 663951013674 Helix-turn-helix domain; Region: HTH_28; pfam13518 663951013675 Winged helix-turn helix; Region: HTH_29; pfam13551 663951013676 Integrase core domain; Region: rve; pfam00665 663951013677 Mu transposase, C-terminal; Region: Mu-transpos_C; pfam09299 663951013678 HMMPfam hit to PF09299, Mu-transpos_C, score 3.7e-27 663951013679 HMMPfam hit to PF00665, rve, score 3.4e-33 663951013680 Predicted helix-turn-helix motif with score 1319.000, SD 3.68 at aa 34-55, sequence QSLSSISKSKGIALSTLYRWNK 663951013681 Site-specific recombinases, DNA invertase Pin homologs [DNA replication, recombination, and repair]; Region: PinR; COG1961 663951013682 Serine Recombinase (SR) family, Resolvase and Invertase subfamily, catalytic domain; members contain a C-terminal DNA binding domain. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and...; Region: SR_ResInv; cd03768 663951013683 catalytic residues [active] 663951013684 catalytic nucleophile [active] 663951013685 Presynaptic Site I dimer interface [polypeptide binding]; other site 663951013686 Synaptic Antiparallel dimer interface [polypeptide binding]; other site 663951013687 Synaptic Flat tetramer interface [polypeptide binding]; other site 663951013688 Synaptic Site I dimer interface [polypeptide binding]; other site 663951013689 Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed...; Region: HTH_Hin_like; cd00569 663951013690 DNA-binding interface [nucleotide binding]; DNA binding site 663951013691 HMMPfam hit to PF02796, HTH_7, score 1.7e-20 663951013692 Predicted helix-turn-helix motif with score 1887.000, SD 5.61 at aa 161-182, sequence TPIKTIAEQWQVSRTTIYRYLN 663951013693 HMMPfam hit to PF00239, Resolvase, score 5e-67 663951013694 PS00398 Site-specific recombinases signature 2. 663951013695 PS00397 Site-specific recombinases active site. 663951013696 Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090 663951013697 dimerization interface [polypeptide binding]; other site 663951013698 putative DNA binding site [nucleotide binding]; other site 663951013699 putative Zn2+ binding site [ion binding]; other site 663951013700 HMMPfam hit to PF01022, HTH_5, score 2.4e-18 663951013701 Predicted helix-turn-helix motif with score 1179.000, SD 3.20 at aa 57-78, sequence LCVCDIANILGVTIANASHHLR 663951013702 PS00846 Bacterial regulatory proteins, arsR family signature. 663951013703 Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371 663951013704 Cation transport ATPase [Inorganic ion transport and metabolism]; Region: ZntA; COG2217 663951013705 metal-binding site [ion binding] 663951013706 E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122 663951013707 Soluble P-type ATPase [General function prediction only]; Region: COG4087 663951013708 HMMPfam hit to PF00403, HMA, score 9.7e-12 663951013709 PS01047 Heavy-metal-associated domain. 663951013710 6 probable transmembrane helices predicted for SATW20_p1220 by TMHMM2.0 at aa 107-124, 134-156, 329-351, 366-388, 672-694 and 699-721 663951013711 HMMPfam hit to PF00122, E1-E2_ATPase, score 5.3e-106 663951013712 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 663951013713 HMMPfam hit to PF00702, Hydrolase, score 1.3e-37 663951013714 PS00154 E1-E2 ATPases phosphorylation site. 663951013715 Probable gene remnant 663951013716 Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3316 663951013717 Integrase core domain; Region: rve; pfam00665 663951013718 HMMPfam hit to PF00665, rve, score 3e-19 663951013719 Predicted helix-turn-helix motif with score 980.000, SD 2.52 at aa 31-52, sequence ISEILRERGVNVHHSTVYRWVQ 663951013721 HMMPfam hit to PF00070, Pyr_redox, score 5.6e-09 663951013722 HMMPfam hit to PF07992, Pyr_redox_2, score 7.7e-09 663951013723 HMMPfam hit to PF02852, Pyr_redox_dim, score 1.8e-35 663951013724 Helix-Turn-Helix DNA binding domain of the MerR1 transcription regulator; Region: HTH_MerR1; cd04783 663951013725 Hg(II)-responsive transcriptional regulator; Region: MerR; TIGR02051 663951013726 DNA binding residues [nucleotide binding] 663951013727 dimer interface [polypeptide binding]; other site 663951013728 mercury binding site [ion binding]; other site 663951013729 Predicted helix-turn-helix motif with score 2172.000, SD 6.58 at aa 3-24, sequence MKISELAKACDVNKETVRYYER 663951013730 HMMPfam hit to PF00376, MerR, score 1.5e-12 663951013731 PS00552 Bacterial regulatory proteins, merR family signature. 663951013732 HMMPfam hit to PF09278, MerR-DNA-bind, score 1.3e-13 663951013733 TlpA-like family; composed of TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a...; Region: TlpA_like_family; cd02966 663951013734 Thioredoxin-like; Region: Thioredoxin_8; pfam13905 663951013735 catalytic residues [active] 663951013736 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 663951013737 HMMPfam hit to PF00578, AhpC-TSA, score 2.2e-07 663951013738 PS00659 Glycosyl hydrolases family 5 signature. 663951013739 Cytochrome c biogenesis protein [Posttranslational modification, protein turnover, chaperones]; Region: CcdA; COG0785 663951013740 6 probable transmembrane helices predicted for SATW20_p1270 by TMHMM2.0 at aa 6-28, 49-71, 81-103, 124-146, 161-183 and 196-218 663951013741 HMMPfam hit to PF02683, DsbD, score 1.5e-05 663951013742 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 663951013743 2 probable transmembrane helices predicted for SATW20_p1280 by TMHMM2.0 at aa 31-53 and 73-95 663951013744 Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371 663951013745 metal-binding site [ion binding] 663951013746 mercuric reductase; Region: MerA; TIGR02053 663951013747 Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070 663951013748 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852 663951013749 HMMPfam hit to PF00403, HMA, score 1.9e-11 663951013750 PS01047 Heavy-metal-associated domain. 663951013751 HMMPfam hit to PF07992, Pyr_redox_2, score 7.4e-66 663951013752 PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 663951013753 HMMPfam hit to PF00070, Pyr_redox, score 1.7e-33 663951013754 HMMPfam hit to PF02852, Pyr_redox_dim, score 8.2e-50