-- dump date 20140620_075924 -- class Genbank::CDS -- table cds_note -- id note YP_251916.1 binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication; can also affect transcription of multiple genes including itself. YP_251917.1 binds the polymerase to DNA and acts as a sliding clamp YP_251918.1 similar to unknown protein YP_251919.1 Required for DNA replication; binds preferentially to single-stranded, linear DNA YP_251922.1 similar to unknown protein YP_251923.1 catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_251924.1 hypothetical protein, similar to branched-chain amino acid transport protein, AzlC family YP_251925.1 similar to unknown protein YP_251926.1 hypothetical protein, similar to homoserine-o-acetyltransferase YP_251927.1 similar to unknown protein YP_251928.1 similar to unknown protein YP_251929.1 in Escherichia coli this protein is wrapped around the base of the L1 stalk YP_251931.1 catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis YP_251934.1 similar to unknown protein YP_251935.1 similar to unknown protein YP_251936.1 no similarity YP_251937.1 hypothetical protein, similar to metal-dependent hydrolases of the beta-lactamase superfamily I YP_251938.1 SPOUT methyltransferase family protein; crystal structure shows homodimer; in Escherichia coli this protein methylates pseudouridine at position 1915 of the 23S ribosomal RNA YP_251939.1 similar to unknown protein YP_251941.1 no similarity YP_251942.1 hypothetical protein, similar to transposase YP_251943.1 hypothetical protein, similar to NADP-dependent alcohol dehydrogenase [truncated] YP_251944.1 similar to unknown protein YP_251946.1 hypothetical protein, similar to kdp operon transcriptional regulatory protein, kdpE YP_251947.1 hypothetical protein, similar to kdp operon sensor protein KdpD YP_251948.1 catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions YP_251949.1 One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions YP_251950.1 one of the components of the high-affinity ATP-driven potassium transport (or KDP)system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions; the C subunit may be involved in assembly of the KDP complex YP_251951.1 no similarity YP_251952.1 hypothetical protein, similar to serine/threonine protein kinase YP_251953.1 no similarity YP_251954.1 similar to unknown protein YP_251955.1 hypothetical protein, similar to surface protein SdrI from Staphylococcus saprophyticus YP_251956.1 hypothetical protein, similar to lipopolysaccharide biosynthesis protein YP_251957.1 similar to unknown protein YP_251958.1 hypothetical protein, similar to 2-nitropropane dioxygenase YP_251959.1 hypothetical protein, similar to LysR-gltR family transcription regulator YP_251960.1 similar to unknown protein YP_251961.1 truncated YP_251962.1 truncated YP_251963.1 truncated YP_251964.1 hypothetical protein, similar to PhnB protein from Bacillus cereus YP_251965.1 hypothetical protein, similar to transcription regulator DeoR family YP_251966.1 no similarity YP_251967.1 no similarity YP_251968.1 similar to unknown protein YP_251969.1 similar to unknown protein YP_251970.1 similar to unknown protein YP_251972.1 similar to unknown protein YP_251973.1 similar to unknown protein YP_251974.1 similar to unknown protein YP_251975.1 similar to unknown protein YP_251976.1 similar to unknown protein YP_251978.1 hypothetical protein, similar to type I restriction-modification system specificity subunit YP_251980.1 no similarity YP_251981.1 no similarity YP_251982.1 similar to unknown protein YP_251983.1 similar to unknown protein YP_251984.1 similar to unknown protein YP_251985.1 hypothetical protein, similar to glycerate dehydrogenase [truncated] YP_251986.1 hypothetical protein, similar to transporter proteins YP_251988.1 hypothetical protein, similar to transcriptional regulators YP_251989.1 truncated YP_251990.1 similar to unknown protein YP_251991.1 truncated YP_251992.1 truncated YP_251993.1 hypothetical protein, similar to transcriptional regulator, TetR family YP_251994.1 hypothetical protein, similar to ABC transporter ecsA-like protein [truncated] YP_251996.1 hypothetical protein, similar to ABC transporter, ATP-binding protein [truncated] YP_251997.1 hypothetical protein, similar to ABC transporter efflux protein DrrB family YP_251998.1 no similarity YP_251999.1 no similarity YP_252000.1 similar to unknown protein YP_252001.1 similar to unknown protein YP_252003.1 hypothetical protein, similar to 3-hydroxy-3-methylglutaryl CoA synthase [truncated] YP_252004.1 glycerophosphoryl diester phosphodiesterase homolog YP_252005.1 similar to unknown protein YP_252007.1 truncated YP_252009.1 hypothetical protein, similar to transcriptional regulator, MerR family YP_252010.1 hypothetical protein, similar to intracellular protease/amidase YP_252011.1 similar to unknown protein YP_252012.1 hypothetical protein, similar to quinone/NADP-dependent oxidoreductase YP_252013.1 similar to unknown protein YP_252015.1 cadmium resistant accessory protein CadX homologue YP_252016.1 catalyzes the reduction of arsenate to arsenite; also can dephosphorylate tyrosine phosphorylated proteins, aryl phosphates, and acyl phosphates YP_252019.1 hypothetical protein, similar to copper-exporting ATPase [truncated] YP_252020.1 hypothetical protein, similar to copper-exporting ATPase [truncated] YP_252021.1 hypothetical protein, similar to multicopper oxidases YP_252022.1 similar to unknown protein YP_252023.1 catalyzes the reduction of arsenate to arsenite; also can dephosphorylate tyrosine phosphorylated proteins, aryl phosphates, and acyl phosphates YP_252027.1 hypothetical protein, similar to arsenical resistance operon trans-acting ArsD YP_252028.1 no similarity YP_252029.1 hypothetical protein, similar to transcriptional regulator of arsR family genes YP_252030.1 similar to unknown protein YP_252031.1 no similarity YP_252032.1 similar to unknown protein YP_252033.1 truncated YP_252035.1 similar to unknown protein YP_252036.1 similar to unknown protein YP_252037.1 similar to unknown protein YP_252038.1 hypothetical protein, similar to transcription regulator YP_252039.1 hypothetical protein, similar to cobalamin synthesis related protein CobW YP_252040.1 hypothetical protein, similar to Zn-binding lipoprotein adcA YP_252041.1 no similarity YP_252042.1 no similarity YP_252043.1 no similarity YP_252044.1 hypothetical protein, similar to acyl carrier protein phosphodiesterase [truncated] YP_252045.1 similar to unknown protein YP_252046.1 similar to unknown protein YP_252047.1 dapE-encoded N-succinyl-L,L-diaminopimelic acid desuccinylase (DapE), catalyzes the hydrolysis of N-succinyl-L,Ldiaminopimelate L,L-SDAP to L,L-diaminopimelate and succinate. It is a metalloprotease containing dinuclear active sites. Its structure is similar to the carboxypeptidase G2 from Pseudomonas sp. strain RS-16 and the aminopeptidase from Aeromonas proteolytica. YP_252048.1 hypothetical protein, similar to regulatory protein (pfoS/R) YP_252049.1 catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr) YP_252050.1 hypothetical protein, similar to ABC transporter ATP-binding protein YP_252051.1 hypothetical protein, similar to ABC transporter YP_252052.1 similar to unknown protein YP_252053.1 no similarity YP_252054.1 hypothetical protein, similar to surface adhesion IcaC YP_252055.1 hypothetical protein, similar to glycosyl transferase cpsK YP_252056.1 hypothetical protein, similar to MntC ABC transporter YP_252057.1 hypothetical protein, similar to metal cation ABC transporter protein YP_252058.1 hypothetical protein, similar to ABC transporter ATP-binding protein YP_252059.1 hypothetical protein, similar to cobalamin synthesis protein cobW YP_252060.1 hypothetical protein, similar to branched-chain amino acid transport system carrier protein YP_252061.1 hypothetical protein, similar to methyltransferase, S-Adenosyl-L-methionine MTase protein YP_252062.1 hypothetical protein, similar to nickel ABC transporter, solute-binding protein YP_252063.1 hypothetical protein, similar to oligopeptide ABC transporter (permease) opp-1B YP_252064.1 hypothetical protein, similar to nickel ABC transporter YP_252065.1 hypothetical protein, similar to oligopeptide transporter ATPase domain opp-1D YP_252066.1 hypothetical protein, similar to nickel transport ATP-binding protein nikE YP_252067.1 similar to unknown protein YP_252068.1 similar to unknown protein YP_252069.1 similar to unknown protein YP_252070.1 hypothetical protein, similar to transmembrane efflux protein YP_252071.1 hypothetical protein, similar to transcription regulator MerR family YP_252072.1 hypothetical protein, similar to 6-pyruvoyl tetrahydropterin synthase YP_252073.1 similar to unknown protein YP_252074.1 hypothetical protein, similar to oxidoreductase [truncated] YP_252075.1 hypothetical protein, similar to dihydrofolate reductase family proteins YP_252076.1 hypothetical protein, similar to ABC transporter permease YP_252077.1 hypothetical protein, similar to ABC transporter ATP-binding protein YP_252079.1 hypothetical protein, similar to oxidoreductase YP_252080.1 similar to unknown protein YP_252081.1 similar to unknown protein YP_252082.1 no similarity YP_252083.1 triacylglycerol lipase (EC 3.1.1.3) precursor homologue YP_252084.1 no similarity YP_252085.1 hypothetical protein, similar to serine protease SplF YP_252086.1 similar to unknown protein YP_252088.1 similar to unknown protein YP_252089.1 hypothetical protein, similar to LacI family transcription repressor YP_252091.1 cytoplasmic mutarotase that catalyzes the conversion between beta-pyran and beta-furan forms of D-ribose; RbsD is required for efficient ribose utilization in E. coli; rbsD-mutant E. coli strains are unable to use ribose as a sole carbon source YP_252095.1 catalyzes the formation of 2-dehydropantoate from (R)-pantoate YP_252096.1 catalyzes the formation of tetrahydrofolate and 2-dehydropantoate from 5,10-methylenetetrahydrofolate and 3-methyl-2-oxobutanoate YP_252097.1 catalyzes the formation of (R)-pantothenate from pantoate and beta-alanine YP_252098.1 Converts L-aspartate to beta-alanine and provides the major route of beta-alanine production in bacteria. Beta-alanine is essential for the biosynthesis of pantothenate (vitamin B5) YP_252100.1 similar to unknown protein YP_252101.1 hypothetical protein, similar to D-alanyl-D-alanine carboxypeptidase YP_252102.1 hypothetical protein, similar to transcriptional regulator, RpiR family YP_252103.1 hypothetical protein, similar to Lactose/Cellobiose specific IIB subunit of PTS system YP_252104.1 phosphotransferase system diacetylchitobiose-specific component IIC homolog YP_252105.1 hypothetical protein, similar to phosphotransferase system (PTS) lichenan-specific enzyme IIA component YP_252106.1 no similarity YP_252107.1 similar to unknown protein YP_252108.1 hypothetical protein, similar to N-acetylglucosamine kinase YP_252109.1 similar to unknown protein YP_252110.1 similar to unknown protein YP_252111.1 similar to unknown protein YP_252113.1 similar to unknown protein YP_252115.1 similar to unknown protein YP_252116.1 no similarity YP_252117.1 similar to unknown protein YP_252118.1 no similarity YP_252120.1 similar to unknown protein YP_252121.1 hypothetical protein, similar to dihydroflavonol-4-reductase [truncated] YP_252122.1 hypothetical protein, similar to dihydroflavonol-4-reductase [truncated] YP_252123.1 xylulose kinase homolog YP_252124.1 ribitol transporter homolog YP_252125.1 3-oxoacyl-(acyl-carrier protein) reductase homolog YP_252126.1 hypothetical protein, similar to ABC transporter ATPase domain YP_252127.1 similar to unknown protein YP_252128.1 proposed role in polysaccahride synthesis YP_252129.1 hypothetical protein, similar to succinate-semialdehyde dehydrogenase YP_252130.1 sorbitol dehydrogenase homolog YP_252131.1 hypothetical protein, similar to transcription regulator YP_252132.1 dihydrolipoamide dehydrogenase homolog YP_252133.1 hypothetical protein, similar to ThiJ, ThiJ/PfpI protease family YP_252134.1 similar to unknown protein YP_252135.1 no similarity YP_252136.1 hypothetical protein, similar to aspartate aminotransferase YP_252137.1 similar to unknown protein YP_252138.1 hypothetical protein, similar to dihydrolipoamide dehydrogenase YP_252139.1 hypothetical protein, similar to branched-chain alpha-keto acid dehydrogenase E1 component YP_252141.1 Catalyzes the transfer of acetyl from acetyldihydrolipoamide to coenzyme A to form acetyl CoA YP_252142.1 hypothetical protein, similar to dihydrolipoamide dehydrogenase YP_252143.1 similar to unknown protein YP_252144.1 similar to unknown protein YP_252145.1 hypothetical protein, similar to short chain dehydrogenase YP_252146.1 similar to unknown protein YP_252149.1 hypothetical protein, similar to transcription antiterminator BglG family YP_252151.1 no similarity YP_252152.1 chloramphenicol-sensitive protein RarD homolog YP_252153.1 no similarity YP_252154.1 hypothetical protein, similar to teichoic acid biosynthesis protein F [frameshifted] YP_252155.1 similar to unknown protein YP_252156.1 similar to unknown protein YP_252157.1 similar to unknown protein YP_252158.1 similar to unknown protein YP_252159.1 similar to unknown protein YP_252160.1 hypothetical protein, partially similar to alkaline phosphatase YP_252161.1 hypothetical protein, similar to ABC transporter binding component YP_252162.1 similar to unknown protein YP_252163.1 similar to unknown protein YP_252164.1 hypothetical protein, similar to mercury resistance operon negative regulator MerR2 YP_252165.1 hypothetical protein, similar to NAD(P)H Oxidoreductase chain B YP_252166.1 no similarity YP_252167.1 no similarity YP_252168.1 no similarity YP_252169.1 similar to unknown protein YP_252170.1 no similarity YP_252171.1 similar to unknown protein YP_252172.1 hypothetical protein, similar to regulatory protein PfoR YP_252173.1 catalyzes the formation of L-citrulline from carbamoyl phosphate and L-ornithine in arginine biosynthesis and degradation YP_252174.2 catalyzes the reversible synthesis of carbamate and ATP from carbamoyl phosphate and ADP YP_252175.1 no similarity YP_252176.1 hypothetical protein, similar to transcriptional regulator PBSX family YP_252177.1 similar to unknown protein YP_252178.1 hypothetical protein, similar to lipoate-protein ligase A YP_252179.1 similar to unknown protein YP_252180.1 similar to unknown protein YP_252181.1 hypothetical protein, similar to glycine cleavage system H protein YP_252182.1 hypothetical protein, similar to alkanal monooxygenase alpha chain YP_252183.1 hypothetical protein, similar to trimethylamine dehydrogenase YP_252184.1 catalyzes the formation of biotin from dethiobiotin and sulfur 2 S-adenosyl-L-methionine YP_252185.1 similar to unknown protein YP_252186.1 similar to unknown protein YP_252187.1 2-oxoglutarate/malate translocator homologue YP_252188.1 similar to unknown protein YP_252189.1 similar to unknown protein YP_252190.1 glycine betaine transporter homolog YP_252191.1 hypothetical protein, similar to N-acetylglucosamine-6-phosphate deacetylase YP_252192.1 no similarity YP_252193.1 N-acetylglucosamine-6-phosphate isomerase homolog YP_252194.1 Converts N-acetylmannosamine-6-phosphate to N-acetylglucosamine-6-phosphate YP_252195.1 hypothetical protein, similar to transcriptional regulator (RpiR family) YP_252196.1 hypothetical protein, similar to glucokinase YP_252197.1 catalyzes the formation of pyruvate and N-acetylmannosamine from N-acetylneuraminic acid YP_252198.1 hypothetical protein, similar to sodium-coupled permease YP_252199.1 similar to unknown protein YP_252200.1 similar to unknown protein YP_252201.1 similar to unknown protein YP_252202.1 similar to unknown protein YP_252203.1 hypothetical protein, similar to ATP-binding protein of nickel transport system YP_252204.1 hypothetical protein, similar to oligopeptide ABC transporter (ATP-binding protein) YP_252205.1 hypothetical protein, similar to nickel transport system (permease) YP_252206.1 hypothetical protein, similar to dipeptide transport system permease protein YP_252207.1 hypothetical protein, similar to nickel ABC transporter, solute-binding protein YP_252209.1 similar to unknown protein YP_252210.1 similar to unknown protein YP_252211.1 hypothetical protein, similar to proton antiporter efflux pump YP_252212.1 hypothetical protein, similar to penicillin amidase (EC 3.5.1.11) YP_252213.1 similar to unknown protein YP_252214.1 hypothetical protein, similar to rhodanase family protein YP_252215.1 Drp35 homologue YP_252216.1 hypothetical protein, similar to phosphomannomutase YP_252217.1 similar to unknown protein YP_252218.1 hypothetical protein, similar to penicillin-binding protein 4 YP_252219.1 hypothetical protein, similar to transcriptional regulator tetR-family YP_252220.1 in group A Streptococci this protein was found to cross react with anti myosin antibodies and may play a role in rheumatic fever YP_252221.1 hypothetical protein, similar to UVRA-like protein/excinuclease ABC subunit A YP_252222.1 hypothetical protein, similar to N-hydroxyarylamine O-acetyltransferase/arylamine N-acetyltransferase YP_252223.1 similar to unknown protein YP_252224.1 hypothetical protein, similar to ABC transporter ATP-binding protein YP_252225.1 similar to unknown protein YP_252226.1 hypothetical protein, similar to transcriptional repressor YP_252227.1 similar to unknown protein YP_252228.1 hypothetical protein, similar to transporter YP_252229.1 no similarity YP_252230.1 similar to unknown protein YP_252231.1 no similarity YP_252232.1 hypothetical protein, similar to phosphatase YP_252233.1 hypothetical protein, similar to alkylphosphonate ABC transporter YP_252234.1 hypothetical protein, similar to phosphate/phosphonate ABC transport system, ATPase component YP_252235.1 hypothetical protein, similar to phosphate/phosphonate ABC transport system, permease subunit YP_252236.1 hypothetical protein, similar to phosphate/phosphonate ABC transport system, permease subunit YP_252237.1 similar to unknown protein YP_252239.1 no similarity YP_252240.1 hypothetical protein, similar to acetyltransferase, GNAT family YP_252241.1 hypothetical protein, similar to cell wall surface anchor family protein YP_252242.1 forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase YP_252243.1 similar to unknown protein YP_252244.1 similar to unknown protein YP_252245.1 similar to unknown protein YP_252246.1 functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; in some organisms, especially gram positive pathogens, have paralogs that have been found to be nonessential but do function in secretion of a subset of exported proteins YP_252247.1 hypothetical protein, similar to glycosyl transferase YP_252248.1 similar to unknown protein YP_252249.1 no similarity YP_252250.1 hypothetical protein, similar to two-component sensor histidine kinase YP_252251.1 hypothetical protein, similar to two-component response regulator YP_252252.1 hypothetical protein, similar to two-component response regulator [truncated] YP_252253.1 no similarity YP_252255.1 hypothetical protein, similar to ABC transporter, periplasmic amino acid-binding protein [truncated] YP_252256.1 no similarity YP_252257.1 similar to unknown protein YP_252258.1 this stereospecific enzymes reduces the S isomer of methionine sulfoxide while MsrB reduces the R form; a fusion protein of this enzyme with MsrB provides protection against oxidative stress in Neisseria gonorrhoeae YP_252259.1 similar to unknown protein YP_252261.1 similar to unknown protein YP_252262.1 hypothetical protein, similar to oxidoreductase (N5,N10-methylenetetrahydromethanopterin reductase) YP_252263.1 hypothetical protein, similar to bicyclomycin resistance protein TcaB YP_252264.1 no similarity YP_252265.1 hypothetical protein, similar to transcriptional regulator (TetR/AcrR family) YP_252266.1 hypothetical protein, similar to glycine betaine ABC transporter permease and substrate binding protein YP_252267.1 hypothetical protein, similar to antibiotic exporters of the RND superfamily YP_252268.1 similar to unknown protein YP_252269.1 hypothetical protein, similar to transcriptional regulator, LysR family YP_252270.1 hypothetical protein, similar to serine/threonine protein phosphatase YP_252271.1 similar to unknown protein YP_252272.1 hypothetical protein, similar to uncharacterized membrane protein YP_252274.1 hypothetical protein, similar to autolysin precursor YP_252275.1 hypothetical protein, similar to phage infection protein YP_252276.1 similar to unknown protein YP_252277.1 hypothetical protein, similar to immunodominant antigen B YP_252279.1 similar to unknown protein YP_252280.1 hypothetical protein, similar to immunodominant antigen B YP_252281.1 hypothetical protein, similar to arginine repressor YP_252282.1 catalyzes the degradation of arginine to citruline and ammonia YP_252284.1 hypothetical protein, similar to transcription regulator Crp/Fnr family YP_252285.1 hypothetical protein, similar to tributyrin esterase YP_252286.1 hypothetical protein, similar to transcriptional regulator (LacI family) YP_252287.1 hypothetical protein, similar to Zn-dependent hydrolase YP_252289.1 similar to unknown protein YP_252290.1 hypothetical protein, similar to capsule biosynthesis protein capA YP_252291.1 hypothetical protein, similar to indole-3-pyruvate decarboxylase YP_252292.1 hypothetical protein, similar to transcriptional regulator YP_252294.1 no similarity YP_252295.1 hypothetical protein, similar to phage-related replication protein YP_252296.1 hypothetical protein, similar to phage-related replication protein YP_252298.1 undetermined role; similar to CarB protein but much smaller YP_252299.1 hypothetical protein, similar to spermidine N1-acetyltransferase YP_252300.1 hypothetical protein, similar to UDP-galactose phosphate transferase involved in capsular polysaccharide synthesis YP_252301.1 FMN-dependent; requires NADH; catalyzes the cleavage of azo bond in aromatic azo compounds YP_252302.1 similar to unknown protein YP_252310.1 hypothetical protein, similar to polysaccharide polymerase YP_252311.1 hypothetical protein, similar to O antigen flippase (transporter) YP_252312.1 hypothetical protein, similar to glucose transferase/glycosyltransferase YP_252313.1 hypothetical protein, similar to glycosyltransferase/capsular polysaccharide synthesis enzyme Cap5L YP_252314.1 hypothetical protein, similar to spore coat polysaccharide biosynthesis protein YP_252315.1 hypothetical protein, similar to lyt expression attenuator LytR YP_252317.1 no similarity YP_252318.1 similar to unknown protein YP_252319.1 hypothetical protein, similar to two-component response regulator YP_252320.1 hypothetical protein, similar to two-component sensor histidine kinase YP_252321.1 hypothetical protein, similar to ABC transporter (ATP-binding protein) YP_252322.1 hypothetical protein, similar to ABC transporter (permease) YP_252323.1 similar to unknown protein YP_252324.1 similar to unknown protein YP_252325.1 similar to unknown protein YP_252326.1 no similarity YP_252327.1 no similarity YP_252328.1 hypothetical protein, similar to 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase) YP_252330.1 hemoprotein; NADPH dependent; with the alpha subunit (a flavoprotein) catalyzes the reduction of sulfite to sulfide YP_252331.1 hypothetical protein, similar to uroporphyrin-III C-methyltransferase YP_252332.1 catalyzes the formation of siroheme from precorrin-2 YP_252333.1 similar to unknown protein YP_252334.1 ATP sulfurylase; ATPS; converts ATP and sulfate to 5'phosphosulfate and pyrophosphate; in some organisms this enzyme is involved in the incorporation of inorganic sulfate while in others it is involved in the production of ATP in the reverse direction; the enzyme from Thermus thermophilus is dimeric and binds a zinc ion that is coordinated by cysteine and histidine residues that are not found in all related proteins but is found in some thermophilic organisms YP_252335.1 converts ATP and adenylyl sulfate to ADP and 3'-phosphoadenylyl sulfate; in Escherichia coli this enzyme functions in cysteine biosynthesis YP_252336.1 hypothetical protein, similar to magnesium citrate secondary transporter YP_252337.1 no similarity YP_252338.1 hypothetical protein, similar to secretory antigen precursor SsaA YP_252339.1 no similarity YP_252340.1 functions in anaerobic transport of C4-dicarboxylate compounds such as fumarate; similar to dcuB YP_252342.1 similar to unknown protein YP_252344.1 catalyzes the oxidation of choline to betaine aldehyde and betain aldehyde to glycine betaine YP_252345.1 hypothetical protein, similar to transcription regulator AraC/XylS family YP_252346.1 hypothetical protein, similar to metal-dependent amidase/aminoacylase/carboxypeptidase YP_252347.1 hypothetical protein, similar to transmembrane efflux pump protein YP_252348.1 hypothetical protein, similar to metal-dependent amidase/aminoacylase/carboxypeptidase YP_252349.1 similar to unknown protein YP_252350.1 similar to unknown protein YP_252352.1 hypothetical protein, similar to glucose 1-dehydrogenase YP_252353.1 hypothetical protein, similar to 3-oxoacyl-(acyl-carrier protein) reductase YP_252354.1 hypothetical protein, similar to transcriptional regulator (LysR family) YP_252355.1 hypothetical protein, similar to transcriptional regulator (LysR family) YP_252356.1 catalyzes the formation of phosphoenolpyruvate from pyruvate YP_252357.1 hypothetical protein, similar to transcription regulator of gluconeogenic genes YP_252358.1 malate dehydrogenase; catalyzes the oxidation of malate to oxaloacetate YP_252359.1 no similarity YP_252360.1 no similarity YP_252361.1 no similarity YP_252362.1 no similarity YP_252363.1 no similarity YP_252364.1 no similarity YP_252365.1 catalyzes the formation of glycerone phosphate and D-glyceraldehyde 3-phosphate from D-fructose 1,6-bisphosphate in glycolysis YP_252366.1 hypothetical protein, similar to DNA topology modulation protein YP_252367.1 similar to unknown protein YP_252368.1 similar to unknown protein YP_252369.1 no similarity YP_252371.1 no similarity YP_252372.1 similar to unknown protein YP_252373.1 similar to unknown protein YP_252374.1 catalyzes the formation of succinate semialdehyde and glutamate from 4-aminobutanoate and 2-oxoglutarate YP_252375.1 hypothetical protein, similar to amino acid transporter YP_252376.1 catalyzes the formation of 2-acetolactate from pyruvate in stationary phase YP_252377.1 hypothetical protein, similar to alpha-acetolactate decarboxylase YP_252378.1 similar to unknown protein YP_252379.1 hypothetical protein, similar to transcriptional regulator tetR-family YP_252380.1 no similarity YP_252381.1 no similarity YP_252382.1 no similarity YP_252383.1 similar to unknown protein YP_252384.1 similar to unknown protein YP_252385.1 similar to unknown protein YP_252386.1 catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway; uses a flavin nucleotide as an essential cofactor; class 2 enzymes are monomeric and compared to the class 1 class 2 possess an extended N terminus, which plays a role in the membrane association of the enzyme and provides the binding site for the respiratory quinones that serve as physiological electron acceptors YP_252387.1 similar to unknown protein YP_252388.1 similar to unknown protein YP_252389.1 similar to unknown protein YP_252390.1 similar to unknown protein YP_252391.1 similar to unknown protein YP_252392.1 similar to unknown protein YP_252393.1 no similarity YP_252395.1 similar to unknown protein YP_252396.1 hypothetical protein, similar to luciferase-like monooxygenase YP_252397.1 hypothetical protein, similar to transcriptional regulator (TetR/AcrR family) YP_252398.1 hypothetical protein, similar to lysostaphin precursor YP_252399.1 hypothetical protein, similar to regulatory protein (PfoS/R) YP_252400.1 similar to unknown protein YP_252401.1 hypothetical protein, similar to immunodominant antigen YP_252402.1 similar to unknown protein YP_252403.1 hypothetical protein, similar to phytoene dehydrogenase YP_252404.1 similar to unknown protein YP_252407.1 hypothetical protein, similar to aspartate aminotransferase YP_252408.1 catalyzes the formation of pyruvate from lactate YP_252409.1 no similarity YP_252410.1 hypothetical protein, similar to mercuric ion-binding protein YP_252412.1 similar to unknown protein YP_252413.1 hypothetical protein, similar to oxidoreductases YP_252414.1 hypothetical protein, similar to O-acetyltransferase YP_252415.1 catalyzes the conversion of 1-proline-5-carboxylate dehydrogenase to L-glutamate YP_252417.1 similar to unknown protein YP_252418.1 hypothetical protein, similar to transcriptional regulator tetR-family YP_252419.1 similar to unknown protein YP_252420.1 similar to unknown protein YP_252421.1 similar to unknown protein YP_252422.1 no similarity YP_252424.1 no similarity YP_252427.1 hypothetical protein, similar to secretory antigen precursor SsaA YP_252428.1 similar to unknown protein YP_252429.1 hypothetical protein, similar to transcriptional regulator YP_252430.1 no similarity YP_252432.1 similar to unknown protein YP_252433.1 hypothetical protein, similar to seritonin transporter YP_252434.1 catalyzes the formation of acetyl phosphate from pyruvate YP_252438.1 hypothetical protein, similar to 4-hydroxybenzoyl-CoA thioesterase YP_252439.1 hypothetical protein, similar to thiol-disulfide isomerase and thioredoxins YP_252440.1 hypothetical protein, similar to L-lactate dehydrogenase YP_252441.1 hypothetical protein, similar to esterase YP_252442.1 no similarity YP_252443.1 truncated YP_252444.1 hypothetical protein, similar to transcriptional regulator YP_252445.1 similar to unknown protein YP_252449.1 similar to unknown protein YP_252450.1 hypothetical protein, similar to gamma-glutamyltranspeptidase YP_252452.1 hypothetical protein, similar to regulatory protein PfoR YP_252453.1 hypothetical protein, similar to beta-subunit of L-serine dehydratase YP_252454.1 hypothetical protein, similar to L-serine dehydratase alpha-subunit YP_252455.1 no similarity YP_252456.1 similar to unknown protein YP_252457.1 hypothetical protein, similar to phosphinothricin acetyltransferase YP_252459.1 similar to unknown protein YP_252460.1 catalyzes the formation of pyruvate from lactate YP_252462.1 aldehyde dehydrogenase homologue YP_252463.1 hypothetical protein, similar to alkylphosphonate ABC transporter YP_252464.1 similar to unknown protein YP_252465.1 similar to unknown protein YP_252466.1 hypothetical protein, similar to Zn-binding lipoprotein adcA YP_252467.1 hypothetical protein, similar to aldehyde dehydrogenase (NAD) YP_252468.1 hypothetical protein, similar to transcriptional regulator (MarR family) YP_252469.1 similar to unknown protein YP_252470.1 hypothetical protein, similar to ABC transporter substrate-binding protein YP_252471.1 hypothetical protein, similar to abhydrolase 2 YP_252472.1 similar to unknown protein YP_252473.1 hypothetical protein, similar to Na(+):H(+) antiporter YP_252475.1 similar to unknown protein YP_252476.1 hypothetical protein, similar to thiamine biosynthesis protein YP_252477.1 functions in thiamine (vitamin B1) biosynthesis; in Bacillus subtilis this enzyme catalyzes the formation of thiazole from dehydroxyglycine and 1-deoxy-D-xylulose-5-phosphate and ThiS-thiocarboxylate YP_252478.1 similar to unknown protein YP_252479.1 hypothetical protein, similar to DAO, FAD dependent oxidoreductase YP_252480.1 hypothetical protein, similar to Thiamine monophosphate synthase TENI YP_252481.1 hypothetical protein, similar to transporter proteins YP_252482.1 similar to unknown protein YP_252483.1 similar to unknown protein YP_252484.1 similar to unknown protein YP_252485.1 hypothetical protein, similar to GTP-pyrophosphokinase YP_252486.1 hypothetical protein, similar to esterases YP_252487.1 hypothetical protein, similar to transcriptional activator regulator YP_252492.1 no similarity YP_252493.1 no similarity YP_252495.1 type II restriction enzyme Sau3AI homolog YP_252496.1 modification methylase Sau3AI homolog YP_252497.1 no similarity YP_252498.1 similar to unknown protein YP_252499.1 similar to unknown protein YP_252500.1 hypothetical protein, similar to oxidoreductase YP_252501.1 catalyzes the formation of L-ornithine from N(2)-acetyl-L-ornithine YP_252502.1 catalyzes the reversible transfer of the terminal phosphate of ATP to form a long chain polyphosphate YP_252504.1 hypothetical protein, similar to aminobenzoyl-glutamate transport protein YP_252505.1 hypothetical protein, similar to glucose 1-dehydrogenase YP_252506.1 hypothetical protein, similar to endo-1,4-beta-glucanase YP_252507.1 similar to unknown protein YP_252509.1 hypothetical protein, similar to glutamate synthase YP_252510.1 similar to unknown protein YP_252511.1 similar to unknown protein YP_252512.1 hypothetical protein, similar to ABC transporter, ATP-binding protein YP_252513.1 similar to unknown protein YP_252514.1 hypothetical protein, similar to two-component sensor histidine kinase YP_252515.1 hypothetical protein, similar to two-component response regulator YP_252516.1 hypothetical protein, similar to chloramphenicol resistance protein YP_252517.1 hypothetical protein, similar to para-nitrobenzyl esterase chain A YP_252518.1 hypothetical protein, similar to amino acid transporter YP_252519.1 similar to unknown protein YP_252520.1 hypothetical protein, similar to L-iditol 2-dehydrogenase YP_252522.1 glycine betaine/carnitine/choline ABC transporter homolog YP_252525.1 in conjunction with LrgA this protein inhibits the expression or activity of extracellular murein hydrolases YP_252526.1 negatively regulates murein hydrolase activity YP_252529.1 hypothetical protein, similar to membrane efflux protein YP_252530.1 ketopantoate reductase; catalyzes the NADPH reduction of ketopantoate to pantoate; functions in pantothenate (vitamin B5) biosynthesis YP_252531.1 no similarity YP_252532.1 similar to unknown protein YP_252533.1 hypothetical protein, similar to dTDP-glucose 4,6-dehydratase YP_252534.1 lipoprotein precursor homolog YP_252535.1 hypothetical protein, similar to beta-lactamase YP_252536.1 hypothetical protein, similar to amino acid permease YP_252537.1 hypothetical protein, similar to sodium-proton exchanger YP_252539.1 similar to unknown protein YP_252540.1 similar to unknown protein YP_252541.1 hypothetical protein, similar to transcriptional activator YP_252542.1 hypothetical protein, similar to S-adenosylmethionine dependent methyltransferase YP_252543.1 involved in peptidoglycan cross-linking YP_252544.1 hypothetical protein, similar to bicyclomycin resistance protein TcaB YP_252545.1 similar to unknown protein YP_252546.1 hypothetical protein, similar to glycerate kinase YP_252547.1 similar to unknown protein YP_252548.1 hypothetical protein, similar to sugar transporter YP_252549.1 hypothetical protein, similar to Cation efflux protein YP_252550.1 hypothetical protein, similar to SceA precursor from Staphylococcus carnosus YP_252551.1 2,3-bisphosphoglycerate-dependent; catalyzes the interconversion of 2-phosphoglycerate to 3-phosphoglycerate YP_252552.1 similar to unknown protein YP_252553.1 hypothetical protein, similar to multidrug resistance transport protein YP_252554.1 hypothetical protein, similar to ABC transporter, periplasmic amino acid-binding protein YP_252555.1 hypothetical protein, similar to amino acid ABC transporter, permease YP_252556.1 hypothetical protein, similar to ABC transporter (ATP binding subunit) YP_252558.1 similar to unknown protein YP_252559.1 disulfide bond protein A dsbG homolog YP_252560.1 hypothetical protein, similar to Zn-binding lipoprotein adcA YP_252561.1 similar to unknown protein YP_252562.1 similar to unknown protein YP_252563.1 similar to unknown protein YP_252564.1 hypothetical protein, similar to NirC protein YP_252565.1 hypothetical protein, similar to formate transporter NirC YP_252571.1 similar to unknown protein YP_252573.1 nitrogen regulation-related NreA protein homolog YP_252574.1 nitrogen regulon two component sensor histidine kinase NreB protein homolog YP_252575.1 nitrogen regulon two-component response regulators NreC protein homolog YP_252577.1 hypothetical protein, similar to small heat shock protein YP_252578.1 hypothetical protein, similar to transcriptional regulator YP_252579.1 similar to unknown protein YP_252582.1 similar to unknown protein YP_252583.1 hypothetical protein, similar to general stress protein 26 YP_252584.1 hypothetical protein, similar to transcription regulatory protein YP_252585.1 similar to unknown protein YP_252587.1 hypothetical protein, similar to cationic transporter YP_252588.1 hypothetical protein, similar to transcriptional regulator tetR-family YP_252589.1 hypothetical protein, similar to phage infection membrane protein precursor YP_252590.1 hypothetical protein, similar to transcription regulator YP_252591.1 similar to unknown protein YP_252592.1 similar to unknown protein YP_252593.1 hypothetical protein, similar to copper transporter [truncated] YP_252594.1 similar to unknown protein YP_252595.1 similar to unknown protein YP_252596.1 hypothetical protein, similar to thioredoxin reductase YP_252597.1 hypothetical protein, similar to a protein involved in attachment to host cells and virulence YP_252598.1 similar to unknown protein YP_252599.1 similar to unknown protein YP_252600.1 similar to unknown protein YP_252601.1 similar to unknown protein YP_252602.1 similar to unknown protein YP_252603.1 similar to unknown protein YP_252604.1 hypothetical protein, similar to transcription repressor of sporulation, septation and degradation paiA YP_252605.1 similar to unknown protein YP_252606.1 L-lactate permease lctP homolog YP_252607.1 hypothetical protein, similar to UDP-glucose:polyglycerol phosphate glucosyltransferase YP_252608.2 malate dehydrogenase; catalyzes the oxidation of malate to oxaloacetate YP_252609.1 similar to unknown protein YP_252610.1 similar to unknown protein YP_252611.1 hypothetical protein, similar to two component histidine kinase sensor protein YP_252612.1 hypothetical protein, similar to two-component response regulator YP_252613.1 hypothetical protein, similar to ABC-transporter permease YP_252614.1 hypothetical protein, similar to ABC transporter, ATP-binding protein YP_252615.1 similar to unknown protein YP_252616.1 transcription regulator TcaR homolog YP_252617.1 TcaA protein homolog YP_252618.1 TcaB protein homolog YP_252619.1 hypothetical protein, similar to transcriptional regulator YP_252620.1 hypothetical protein, similar to multidrug resistance protein A YP_252621.1 hypothetical protein, similar to multidrug-efflux transporter YP_252622.1 similar to unknown protein YP_252623.1 hypothetical protein, similar to esterase YP_252624.1 similar to unknown protein YP_252625.1 similar to unknown protein YP_252626.1 hypothetical protein, similar to divalent cation transporter YP_252627.1 catalyzes the isomerization of isopentenyl pyrophosphate to dimethylallyl diphosphate YP_252628.1 hypothetical protein, similar to sodium/glutamate symporter YP_252629.1 hypothetical protein, similar to DNA-3-methyladenine glycosidase YP_252630.1 hypothetical protein, similar to transcriptional regulator YP_252631.1 no similarity YP_252632.1 similar to unknown protein YP_252633.1 hypothetical protein, similar to aldose 1-epimerase YP_252634.1 similar to unknown protein YP_252635.1 catalyzes D-ribose 5-phosphate --> D-ribulose 5-phosphate in the nonoxidative branch of the pentose phosphate pathway YP_252637.1 similar to unknown protein YP_252638.1 catalyzes the formation of glutamate and formamide from N-formimidoyl-L-glutamate YP_252639.1 hypothetical protein, similar to sulfate permease [truncated] YP_252640.1 truncated YP_252641.1 hypothetical protein, similar to amino acid amidohydrolase YP_252642.1 hypothetical protein, similar to oxidoreductase YP_252643.1 nitrilotriacetate monooxygenase component B homolog YP_252644.1 hypothetical protein, similar to Na+/H+ antiporter YP_252645.1 similar to unknown protein YP_252646.1 hypothetical protein, similar to transcriptional regulator YP_252648.1 similar to unknown protein YP_252649.1 hypothetical protein, similar to phosphoglycolate phosphatase YP_252650.1 similar to unknown protein YP_252651.1 no similarity YP_252652.1 similar to unknown protein YP_252653.1 similar to unknown protein YP_252654.1 hypothetical protein, similar to amino-acid transporter protein YP_252655.1 hypothetical protein, similar to transcriptional regulator, RpiR family YP_252656.1 sucrose-specific PTS system IIBC component homolog YP_252657.1 catalyzes the cleavage of the lactyl ether moiety of N-acetylmuramic acid-6-phosphate (MurNAc-6-P) to form N-acetylglucosamine-6-phosphate (GlcNAc-6-P) and lactate; involved in MurNAc dissimilation pathway YP_252658.1 similar to unknown protein YP_252659.1 no similarity YP_252660.1 similar to unknown protein YP_252661.1 hypothetical protein, similar to myo-inositol-1(or 4)-monophosphatase YP_252662.1 hypothetical protein, similar to lyt divergon expression attenuator LytR YP_252663.1 formate dehydrogenase homolog YP_252664.1 similar to unknown protein YP_252665.1 hypothetical protein, similar to autolysin E YP_252666.1 hypothetical protein, similar to monooxygenase YP_252667.1 Catalyzes the reduction of hydroxypyruvate to form D-glycerate, using NADH as an electron donor YP_252668.1 hypothetical protein, similar to chaperonin protein YP_252669.1 hypothetical protein, similar to chaperonin protein YP_252670.1 hypothetical protein, similar to secretory antigen precursor SsaA YP_252671.1 similar to unknown protein YP_252672.1 hypothetical protein, similar to D-octopine dehydrogenase YP_252673.1 hypothetical protein, similar to Na+/H+ antiporter YP_252674.1 truncated YP_252676.1 truncated YP_252677.1 secretory antigen precursor SsaA homolog YP_252678.1 hypothetical protein, similar to transcription regulator [truncated] YP_252679.1 hypothetical protein, similar to staphylococcal accessory regulator A YP_252680.1 similar to unknown protein YP_252681.1 staphylococcal accessory regulator SarR homolog YP_252682.1 hypothetical protein, similar to butyryl-CoA dehydrogenase YP_252683.1 hypothetical protein, similar to ferrichrome ABC transporter FhuD YP_252684.1 hypothetical protein, similar to inosine-adenosine-guanosine-nucleoside hydrolase YP_252685.1 hypothetical protein, similar to biotin biosynthesis protein YP_252686.1 similar to unknown protein YP_252687.1 involved in the production or activity of formate dehydrogenase-H which is active when nitrate is not present during anaerobic growth YP_252688.1 molybdate-binding protein homolog YP_252689.1 molybdenum transport permease homolog YP_252690.1 molybdenum transport ATP-binding protein homolog YP_252691.1 molybdopterin biosynthesis protein moeB homolog YP_252692.1 molybdopterin precursor biosynthesis moaB homolog YP_252693.1 MoaC; along with MoaA is involved in conversion of a guanosine derivative into molybdopterin precursor Z; involved in molybdenum cofactor biosynthesis YP_252694.1 molybdopterin biosynthesis protein moeA homolog YP_252695.1 molybdopterin-guanine dinucleotide biosynthesis mobB homolog YP_252697.1 molybdopterin synthase small subunit homolog YP_252698.1 in Escherichia coli MobA links a guanosine 5'-phosphate to molydopterin to form molybdopterin guanine dinucleotide during molybdenum cofactor biosynthesis YP_252699.1 molybdenum cofactor biosynthesis protein A homolog YP_252700.1 similar to unknown protein YP_252701.1 hypothetical protein, similar to transporter protein YP_252702.1 hypothetical protein, similar to transcription regulator MarR family YP_252703.1 similar to unknown protein YP_252704.1 no similarity YP_252706.1 hypothetical protein, similar to acriflavin resistance protein YP_252707.1 similar to unknown protein YP_252708.1 similar to unknown protein YP_252709.1 similar to unknown protein YP_252710.1 glucose-1-dehydrogenase homolog YP_252711.1 glucose uptake protein homolog YP_252712.1 hypothetical protein, similar to acetyltransferase, GNAT family YP_252713.1 decatenates replicating daughter chromosomes YP_252715.1 similar to unknown protein YP_252716.1 NusE; involved in assembly of the 30S subunit; in the ribosome, this protein is involved in the binding of tRNA; in Escherichia coli this protein was also found to be involved in transcription antitermination; NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination; binding of NusB/S10 to boxA nucleates assembly of the antitermination complex YP_252717.1 binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin YP_252718.1 L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA YP_252719.1 binds third domain of 23S rRNA and protein L29; part of exit tunnel YP_252720.1 one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation YP_252721.1 protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA YP_252722.1 binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center YP_252723.1 forms a complex with S10 and S14; binds the lower part of the 30S subunit head and the mRNA in the complete ribosome to position it for translation YP_252724.1 located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e YP_252725.1 one of the stabilizing components for the large ribosomal subunit YP_252726.1 primary binding protein; helps mediate assembly; involved in translation fidelity YP_252727.1 binds to the 23S rRNA between the centers for peptidyl transferase and GTPase YP_252728.1 assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel YP_252729.1 part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13 YP_252730.1 located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group appear to contain the zinc-binding motif YP_252731.1 binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit YP_252732.1 ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance YP_252733.1 binds 5S rRNA along with protein L5 and L25 YP_252734.1 located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance YP_252735.1 L30 binds domain II of the 23S rRNA and the 5S rRNA; similar to eukaryotic protein L7 YP_252736.1 late assembly protein YP_252737.1 forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase YP_252738.1 essential enzyme that recycles AMP in active cells; converts ATP and AMP to two molecules of ADP YP_252739.1 stimulates the activities of the other two initiation factors, IF-2 and IF-3 YP_252740.1 smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group have the motif YP_252741.1 located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA YP_252742.1 located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3 YP_252743.1 catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme YP_252744.1 is a component of the macrolide binding site in the peptidyl transferase center YP_252746.1 with CbiNQ forms the ABC transporter for cobalt import; Staphylococcus has two adjacent copies of this gene YP_252747.1 with CbiNQ forms the ABC transporter for cobalt import; Staphylococcus has two adjacent copies of this gene YP_252748.1 hypothetical protein, similar to nonorganic iron transporter membrane permease YP_252749.1 mediates pseudouridylation (positions 38, 39, 40) at the tRNA anticodon region which contributes to the structural stability YP_252750.1 in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit YP_252751.1 forms a direct contact with the tRNA during translation YP_252752.1 similar to unknown protein YP_252753.1 Modulates the activities of several enzymes which are inactive in their acetylated form YP_252755.1 no similarity YP_252757.1 catalyzes the interconversion of galactose 6-phosphate to tagatose 6-phosphate; tagatose pathway for galactose utilization YP_252758.1 catalyzes the interconversion of galactose 6-phosphate to tagatose 6-phosphate YP_252759.1 catalyzes the formation of tagatose 1,6-bisphosphate from tagatose 6-phosphate and ATP YP_252760.1 catalyzes the reversible reaction of dihydroxyacetone phosphate with glyceraldehyde 3-phosphate to produce tagatose 1,6-bisphosphate; in Streptococcus pyogenes there are two paralogs of tagatose-bisphosphate aldolase, encoded by lacD1 and lacD2; expression of lacD1 is highly regulated by environmental conditions while lacD2 specializes in an efficient utilization of carbohydrate sources YP_252763.1 catalyzes the formation of 6-phospho-galactose from a 6-phospho-beta-galactoside YP_252764.1 no similarity YP_252765.1 similar to unknown protein YP_252766.1 hypothetical protein, similar to luciferase-like monooxygenase YP_252767.1 hypothetical protein, similar to arginate lyase YP_252768.1 glycine betaine transporter opuD homolog YP_252769.1 similar to unknown protein YP_252770.1 similar to unknown protein YP_252771.1 alkaline shock protein 23 homolog YP_252772.1 truncated YP_252773.1 no similarity YP_252774.1 similar to unknown protein YP_252775.1 hypothetical protein, similar to transporter YP_252776.1 similar to unknown protein YP_252777.1 similar to unknown protein YP_252778.1 hypothetical protein, similar to ferrichrome ABC transporter binding protein YP_252779.1 hypothetical protein, similar to ferrichrome ABC transporter permease subunit YP_252780.1 hypothetical protein, similar to ferrichrome ABC transporter permease subunit YP_252781.1 similar to unknown protein YP_252782.1 iron regulated; catalyzes the release of heme from hemoglobin allowing bacterial pathogens to use the host heme as an iron source YP_252783.1 similar to unknown protein YP_252784.1 similar to unknown protein YP_252785.1 hypothetical protein, similar to UDP-N-acetylglucosamine pyrophosphorylase YP_252786.1 hypothetical protein, similar to hemolysin III YP_252787.1 hypothetical protein, similar to multidrug transporter YP_252788.1 similar to unknown protein YP_252789.1 hypothetical protein, similar to multidrug resistance transporter protein YP_252790.1 hypothetical protein, similar to ATP-binding Mrp-like protein YP_252792.1 similar to unknown protein YP_252793.1 similar to unknown protein YP_252794.1 catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate YP_252795.1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source YP_252796.1 hypothetical protein, similar to ABC transporter YP_252797.1 similar to unknown protein YP_252798.1 no similarity YP_252799.1 truncated YP_252800.1 truncated YP_252801.1 hypothetical protein, similar to lytic regulatory protein YP_252802.1 similar to unknown protein YP_252803.1 cation-efflux system membrane protein homolog YP_252804.1 repressor protein ArsR family homolog YP_252805.1 similar to unknown protein YP_252806.1 hypothetical protein, similar to mannnose-6 phospate isomelase pmi YP_252807.1 similar to unknown protein YP_252808.1 similar to unknown protein YP_252809.1 similar to unknown protein YP_252810.1 general stress protein 20U homolog YP_252811.1 catalyzes the reversible phosphorolysis of ribonucleosides and 2'- deoxyribonucleosides to the free base and (2'-deoxy)ribose-1- phosphate YP_252812.1 catalyzes the formation of D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-D-ribose-5-phosphate YP_252813.1 Catalyzes the reversible phosphorolysis of pyrimidines in the nucleotide synthesis salvage pathway YP_252814.1 catalyzes the transfer of phosphate between the C1 and C5 carbons of pentose YP_252815.1 similar to unknown protein YP_252816.1 catalyzes the hydrolysis of S-ribosylhomocysteine to homocysteine and autoinducer-2 YP_252817.1 HmrA protein homolog YP_252818.1 similar to unknown protein YP_252819.1 similar to unknown protein YP_252820.1 catalyzes the formation of (R)-4'-phosphopantothenate from (R)-pantothenate in coenzyme A biosynthesis; type II pantothenate kinases are not regulated by feedback inhibition by coenzyme A YP_252821.1 hypothetical protein, similar to spermine/spermidine acetyltransferase blt YP_252822.2 participates in both the initiation and recycling phases of transcription; in the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling YP_252823.1 CTP synthase; CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer YP_252824.1 similar to unknown protein YP_252825.1 catalyzes the formation of glycerone phosphate and glyceraldehyde 3-phosphate from fructose 1,6, bisphosphate; induced by anaerobic conditions in Bacillus subtilis YP_252826.1 adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active YP_252827.1 similar to unknown protein YP_252828.1 hypothetical protein, similar to aldehyde dehydrogenase YP_252829.1 An RNA-DNA helicase that actively releases nascent mRNAs from paused transcription complexes YP_252830.1 RpmE2; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster do not have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome YP_252831.1 catalyzes the formation of thymidine 5'-phosphate from thymidine YP_252832.1 recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2 YP_252833.1 hypothetical protein, similar to protoporphyrinogen oxidase (hemK) YP_252834.1 similar to unknown protein YP_252835.1 hypothetical protein, similar to protein-tyrosine-phosphatase YP_252836.1 similar to unknown protein YP_252837.1 catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate YP_252838.1 Catalyzes the formation of uracil and 5-phospho-alpha-D-ribosy 1-diphosphate from UMP and diphosphate YP_252840.1 similar to unknown protein YP_252841.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0 YP_252842.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit C is part of the membrane proton channel F0 YP_252843.1 produces ATP from ADP in the presence of a proton gradient across the membrane; subunit B is part of the membrane proton channel YP_252844.1 Produces ATP from ADP in the presence of a proton gradient across the membrane; the delta subunit is part of the catalytic core of the ATP synthase complex YP_252845.1 produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit YP_252846.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is a regulatory subunit YP_252847.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit YP_252848.1 part of catalytic core of ATP synthase; alpha(3)beta(3)gamma(1)delta(1)epsilon(1); involved in producing ATP from ADP in the presence of the proton motive force across the membrane YP_252849.1 similar to unknown protein YP_252850.1 adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active YP_252851.1 in Pseudomonas aeruginosa this enzyme is a trimer of dimers; essential for membrane formation; performs third step of type II fatty acid biosynthesis; catalyzes dehydration of (3R)-hydroxyacyl-ACP to trans-2-acyl-ACP YP_252852.1 similar to unknown protein YP_252853.1 hypothetical protein, similar to single-strand DNA binding protein YP_252854.1 hypothetical protein, similar to immunodominant antigen SceD precursor from Staphylococcus carnosus YP_252855.1 trasncription activator TenA homolog YP_252856.1 catalyzes the formation of 4-amino-2-methyl-5-diphosphomethylpyrimidine YP_252857.1 catalyzes the formation of 4-methyl-5-(2-phosphoethyl)-thiazole and ADP from 4-methyl-5-(2-hydroxyethyl)-thiazole and ATP YP_252858.1 Condenses 4-methyl-5-(beta-hydroxyethyl)-thiazole monophosphate and 4-amino-5-hydroxymethyl pyrimidine pyrophosphate to form thiamine monophosphate YP_252861.1 similar to unknown protein YP_252862.1 hypothetical protein, similar to cardiolipin synthetase YP_252863.1 similar to unknown protein YP_252864.1 similar to unknown protein YP_252865.1 similar to unknown protein YP_252866.1 no similarity YP_252868.1 hypothetical protein, similar to rod-shape determining protein RodA YP_252869.1 D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli YP_252871.1 hypothetical protein, similar to ATP-dependent RNA helicase YP_252872.1 similar to unknown protein YP_252873.1 similar to unknown protein YP_252874.1 similar to unknown protein YP_252875.1 Catalyzes the formation of holo-ACP, which mediates the essential transfer of acyl fatty acid intermediates during the biosynthesis of fatty acids and lipids YP_252877.1 similar to unknown protein YP_252881.1 binds to sigma-B preventing the formation of an RNA polymerase holoenzyme YP_252882.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; sigma B is not essential for sporulation; rather it is required for maximal expression of ctc and csbA which are transcribed in the early stationary phase under conditions inimical to sporulation; induced by heat shock, salt stress, oxidative stress, glucose limitation, oxygen limitation and entry into stationary phase YP_252883.1 hypothetical protein, similar to transcription accessory protein (S1 RNA binding domain) YP_252884.1 similar to unknown protein YP_252885.1 no similarity YP_252887.1 catalyzes the formation of 2-oxobutanoate from L-threonine; biosynthetic YP_252888.1 catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate in leucine biosynthesis; forms a heterodimer of LeuC/D YP_252889.1 dehydratase component, catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate YP_252890.1 catalyzes the oxidation of 3-isopropylmalate to 3-carboxy-4-methyl-2-oxopentanoate in leucine biosynthesis YP_252891.1 catalyzes the formation of 2-isopropylmalate from acetyl-CoA and 2-oxoisovalerate in leucine biosynthesis YP_252892.1 catalyzes the formation of (R)-2,3-dihydroxy-3-methylbutanoate from (S)-2-hydroxy-2-methyl-3-oxobutanoate in valine and isoleucine biosynthesis YP_252893.1 with IlvI catalyzes the formation of 2-acetolactate from pyruvate, this subunit subunit is required for full activity and valine sensitivity; also known as acetolactate synthase small YP_252895.1 catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis YP_252896.1 hypothetical protein, similar to ATPase or kinase YP_252897.1 hypothetical protein, similar to glycoprotein endopeptidase YP_252898.1 hypothetical protein, similar to ribosomal protein-alanine N-acetyltransferase YP_252899.1 in most organisms, only the N-terminal domain is present in a single polypeptide; in some archaea this domain is fused to a kinase domain; this gene is essential for growth in Escherichia coli and Bacillus subtilis; the secreted glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins; the Pyrococcus structure shows DNA-binding properties, iron-binding, ATP-binding, and AP endonuclease activity YP_252900.1 ABC transporter ATP-binding protein vga homolog YP_252901.1 modulates transcription in response to the NADH/NAD(+) redox state YP_252902.1 hypothetical protein, similar to transporter permease protein YP_252903.1 similar to unknown protein YP_252904.1 ammonium transporter homolog YP_252907.1 hypothetical protein, similar to fructokinase YP_252912.1 hypothetical protein, similar to nitrilase YP_252913.1 nitroreductase family protein homolog YP_252914.1 hypothetical protein, similar to serine-aspartate repeat protein sdrZ YP_252915.1 hypothetical protein. similar to CAAX amino terminal protease family protein YP_252916.1 10 kDa chaperonin; Cpn10; GroES; forms homoheptameric ring; binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it; folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES; release of the folded substrate is dependent on ATP binding and hydrolysis in the trans ring YP_252917.1 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth YP_252918.1 hypothetical protein, similar to integrase YP_252919.1 no similarity YP_252921.1 similar to unknown protein YP_252922.1 no similarity YP_252924.1 no similarity YP_252925.1 no similarity YP_252926.1 similar to unknown protein YP_252927.1 hypothetical protein, similar to a protein from Staphylococcus aureus phage phi 12 YP_252928.1 no similarity YP_252929.1 no similarity YP_252930.1 no similarity YP_252931.1 hypothetical protein, similar to sporulation-control protein Spo0M YP_252932.1 similar to unknown protein YP_252933.1 hypothetical protein, similar to aspartate transaminase YP_252934.1 hypothetical protein, similar to transcriptional regulator (GntR family) YP_252935.1 similar to unknown protein YP_252936.1 hypothetical protein, similar to transcriptional regulator (GntR family) YP_252937.1 hypothetical protein, similar to ABC transporter ATB-binding subunit YP_252938.1 similar to unknown protein YP_252939.1 hypothetical protein, similar to ABC transporter, ATP-binding protein YP_252940.1 similar to unknown protein YP_252941.1 hypothetical protein, similar to thioredoxin YP_252942.1 similar to unknown protein YP_252943.1 similar to unknown protein YP_252944.1 similar to unknown protein YP_252945.1 similar to unknown protein YP_252946.1 similar to unknown protein YP_252947.1 similar to unknown protein YP_252949.1 catalyzes the hydrolysis of pyrophosphate to phosphate YP_252950.1 pyrazinamidase/nicotinamidase homolog YP_252951.1 similar to unknown protein YP_252952.1 hypothetical protein, similar to chorismate mutase/prephenate dehydratase (pheA) YP_252953.1 nitric-oxide synthase homolog YP_252954.2 catalyzes the formation of 5-phospho-alpha-D-ribose 1-diphosphate and nicotinate from nicotinate D-ribonucleotide and diphosphate YP_252955.1 catalyzes the formation of nicotinamide adenine dinucleotide (NAD) from nicotinic acid adenine dinucleotide (NAAD) using either ammonia or glutamine as the amide donor and ATP; ammonia-utilizing enzymes include the ones from Bacillus and Escherichia coli while glutamine-utilizing enzymes include the Mycobacterial one; forms homodimers YP_252956.1 similar to unknown protein YP_252957.1 similar to unknown protein YP_252958.1 Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide YP_252959.1 similar to unknown protein YP_252960.1 PcrB-like protein; GGGP synthase; member of prenyltransferases that transfer isoprenoid groups to nonisoprenoid acceptors; functions in form GGGP from glycerol-1-phosphate (G-1-P) and geranylgeranyl pyrophosphate (GGPP); important in lipid metabolism and especially important as the ether linkages in archaea are different than those in bacteria; GGGP synthase lies at the branch point for membrane lipid biosynthesis; cytosolic; T acidophilum protein acts as a homodimer while M thermoautotrophicum protein has been reported to function as a pentamer YP_252966.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; some Mycoplasma proteins contain an N-terminal fusion to an unknown domain YP_252967.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA YP_252968.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA YP_252969.1 no similarity YP_252970.1 similar to YegS from E. coli YP_252971.1 RNA methyltransferase homolog YP_252972.1 hypothetical protein, similar to a transcription regulator YP_252973.1 involved in translesion DNA polymerization with beta clamp of polymerase III; belongs to Y family of polymerases; does not contain proofreading function YP_252974.1 hypothetical protein, similar to DNA polymerase III, alpha chain PolC type YP_252975.1 hypothetical protein, similar to ferritin YP_252976.1 hypothetical protein, similar to UDP-N-acetylmuramyl tripeptide synthetase YP_252977.1 hypothetical protein, similar to cobyric acid synthase CobQ YP_252978.1 similar to unknown protein YP_252979.1 catalyzes the removal of N-terminal amino acids from peptides and arylamides; generally Co(II) however activity has been shown for some methionine aminopeptidases with Zn, Fe, or Mn YP_252980.1 hypothetical protein, similar to 3(or 17)beta-hydroxysteroid dehydrogenase (EC 1.1.1.51) I YP_252981.1 no similarity YP_252982.1 hypothetical protein, similar to high-affinity nickel-transport protein YP_252983.1 similar to unknown protein YP_252984.1 similar to unknown protein YP_252988.1 hypothetical protein, similar to transporter YP_252989.1 similar to unknown protein YP_252990.1 hypothetical protein, similar to protein-tyrosine phosphatase YP_252991.1 similar to unknown protein YP_252993.1 hypothetical protein, similar to acyl-CoA thioester hydrolase YP_252994.1 no similarity YP_252995.1 truncated YP_252996.1 truncated YP_252997.1 hypothetical protein, similar to thioredoxin-like oxidoreductases YP_252998.1 similar to unknown protein YP_252999.1 similar to unknown protein YP_253001.1 monofunctional; catalyzes the elongation of glycan strands in cell wall biosynthesis YP_253002.1 binds RecA and inhibits RecA-mediated DNA strand exchange and ATP hydrolysis and coprotease activities YP_253003.1 hypothetical protein, similar to transcriptional regulator YP_253004.1 hypothetical protein, similar to teichoic acid translocation ATP-binding protein tagH YP_253005.1 hypothetical protein, similar to teichoic acid transport protein tagG YP_253007.1 similar to unknown protein YP_253008.1 hypothetical protein, similar to A/G-specific adenine glycosylase YP_253009.1 similar to unknown protein YP_253010.1 hypothetical protein, similar to ABC transporter (ATP-binding protein) YP_253011.1 similar to unknown protein YP_253012.2 converts (S)-4-amino-5-oxopentanoate to 5-aminolevulinate YP_253013.1 hypothetical protein, similar to bacterioferritin comigratory protein YP_253014.1 hypothetical protein, similar to D-3-phosphoglycerate dehydrogenase YP_253016.1 no similarity YP_253017.1 transcription regulator Fur family homolog (transcription regulators, PerR in B. subtilis) YP_253018.1 hypothetical protein, similar to regulatory protein (pfoS/R) YP_253019.1 hypothetical protein, similar to glutamine-binding periplasmic protein YP_253021.1 hypothetical protein; similar to 4Fe-4S ferredoxin YP_253022.1 hypothetical protein, similar to SpoU rRNA methylase family YP_253023.1 similar to unknown protein YP_253024.1 similar to unknown protein YP_253025.1 similar to unknown protein YP_253026.1 class II family (does not require metal); tetrameric enzyme; fumarase C; reversibly converts (S)-malate to fumarate and water; functions in the TCA cycle YP_253027.1 hypothetical protein, similar to ribosomal large subunit pseudouridine synthase YP_253028.1 hypothetical protein, similar to histidine kinase-like ATPases YP_253029.1 hypothetical protein, similar to two-component response regulator YP_253030.1 similar to unknown protein YP_253031.1 similar to unknown protein YP_253032.1 similar to unknown protein YP_253033.1 similar to unknown protein YP_253034.1 similar to unknown protein YP_253035.1 catalyzes the exonucleic cleavage of mRNA yielding nucleioside 5'-phosphates YP_253037.1 similar to unknown protein YP_253038.1 similar to unknown protein YP_253040.1 hypothetical protein, similar to ABC transporter (ATP-binding protein) YP_253041.1 hypothetical protein, similar to ABC transporter YP_253043.1 catalyzes the formation of coproporphyrinogen from uroporphyrinogen III YP_253044.1 protoheme ferro-lyase; catalyzes the insertion of a ferrous ion into protoporphyrin IX to form protoheme; involved in protoheme biosynthesis; in some organisms this protein is membrane-associated while in others it is cytosolic YP_253045.1 catalyzes the formation of protoporphyrin IX from protoporphyrinogen IX YP_253046.1 similar to unknown protein YP_253049.1 hypothetical protein, similar to alpha-hemolysin YP_253050.1 similar to unknown protein YP_253051.1 similar to unknown protein YP_253052.1 PEP carboxykinase; PEP carboxylase; PEPCK; catalyzes the phosphorylation and decarboxylation of oxaloacetate to form phosphoenolpyruvate using ATP YP_253053.1 no similarity YP_253054.1 methionine adenosyltransferase; catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase YP_253055.1 similar to unknown protein YP_253056.1 plant metabolite dehydrogenase homolog YP_253057.1 hypothetical protein, similar to CrcB protein involved in chromosome condensation YP_253058.1 may be involved in chromosome condensation; overexpression in Escherichia coli protects against decondensation by camphor; overexpressing the protein results in an increase in supercoiling YP_253059.1 similar to unknown protein YP_253060.1 similar to novel fructose-6-phosphate aldolase from Escherichia coli; enzyme from Methanocaldococcus janaschii shows transaldolase activity YP_253061.1 similar to unknown protein YP_253062.1 similar to unknown protein YP_253063.1 similar to unknown protein YP_253064.1 similar to unknown protein YP_253067.1 similar to unknown protein YP_253069.1 catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine YP_253071.1 RibE; 6,7-diimethyl-8-ribityllumazine synthase; DMRL synthase; lumazine synthase; beta subunit of riboflavin synthase; condenses 5-amino-6-(1'-D)-ribityl-amino-2,4(1H,3H)-pyrimidinedione with L-3,4-dihydrohy-2-butanone-4-phosphate to generate 6,6-dimethyl-8-lumazine (DMRL); riboflavin synthase then uses 2 molecules of DMRL to produce riboflavin (vitamin B12); involved in the last steps of riboflavin biosynthesis; forms a 60mer (icosahedral shell) in both Bacillus subtilis and Escherichia coli; in Bacillus subtilis this 60mer is associated with the riboflavin synthase subunit (alpha) while in Escherichia coli it is not YP_253072.1 proline dehydrohenase homolog YP_253073.1 lysophospholipase homolog YP_253075.1 hypothetical protein, similar to SAM-dependent methyltransferase YP_253076.1 similar to unknown protein YP_253077.1 multidrug resistance protein homolog YP_253078.1 leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase YP_253079.1 hypothetical protein, similar to molybdopterin biosynthesis MoeB protein YP_253080.1 hypothetical protein, similar to FmtB/extracellular matrix binding protein YP_253081.1 hypothetical protein, similar to FmtB protein YP_253082.1 hypothetical protein, similar to pyridine nucleotide-disulphide oxidoreductase YP_253083.1 spore cortex protein homolog YP_253085.1 similar to unknown protein YP_253086.1 divalent metal ion-dependent extracellular dipeptidase; able to hydrolyze a broad range of dipeptides but no tri-, tetra-, or larger oligopeptides; differences in the amino acid specificity of the cleavage site varies between species; similar to succinyl-diaminopimelate desuccinylases YP_253088.1 hypothetical protein, similar to choline/ethanolamine kinase YP_253089.1 tRNA (guanine-N(7)-)-methyltransferase; catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA by transferring the methyl residue from S-adenosyl-L-methionine YP_253090.1 hypothetical protein, similar to metallo-beta-lactamase superfamily YP_253091.1 similar to unknown protein YP_253092.1 hypothetical protein, similar to endo-1,4-beta-glucanase (EC 3.2.1.4) YP_253093.1 thioredoxin homolog YP_253094.1 similar to unknown protein YP_253095.1 hypothetical protein, similar to phenylalanyl-tRNA synthetase YP_253096.1 hypothetical protein, similar to DNA translocase stage III sporulation protein YP_253097.1 Catalyzes the formation of UDP-N-acetylmuramoyl-L-alanine from UDP-N-acetylmuramate and L-alanine in peptidoglycan synthesis YP_253098.1 hypothetical protein, similar to general stress protein YP_253099.1 hypothetical protein, similar to smooth muscle caldesmon YP_253100.1 catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate YP_253104.1 Acs; catalyzes the conversion of acetate and CoA to acetyl-CoA YP_253105.1 catalyzes the formation of 10-formyltetrahydrofolate from formate and tetrahydrofolate YP_253106.1 transglycosylase SgtA homolog YP_253108.1 hypothetical protein, similar to transcriptional regulator, MarR family YP_253109.1 hypothetical protein, similar to membrane-bound transport protein YP_253111.1 hypothetical protein, similar to serine proteinase Do, heat-shock protein htrA YP_253112.1 hypothetical protein, similar to 1-acylglycerol-3-phosphate O-acyltransferase YP_253114.1 similar to unknown protein YP_253115.1 catalyzes the formation of 3-phosphonooxypyruvate from 3-phospho-D-glycerate in serine biosynthesis; can also reduce alpha ketoglutarate to form 2-hydroxyglutarate YP_253116.1 hypothetical protein, similar to transaminase YP_253117.1 hypothetical protein, similar to organic hydroperoxide resistance protein YP_253118.1 hypothetical protein, similar to glycerophosphoryl diester phosphodiesterase YP_253120.1 no similarity YP_253121.1 primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination YP_253122.1 similar to unknown protein YP_253123.1 acts to negatively regulates ftsZ ring formation by modulating the frequency and position of the ftsZ ring formation YP_253124.1 hypothetical protein, similar to L-cysteine sulfurtransferase YP_253125.1 Required for the synthesis of the thiazole moiety YP_253126.1 hypothetical protein, similar to transporter YP_253127.1 antioxidant activity; thioredoxin-dependent thiol peroxidase; forms homodimers in solution; shows substrate specificity to alkyl hydroperoxides; periplasmic protein YP_253129.1 AckA utilizes acetate and can acetylate CheY which increases signal strength during flagellar rotation; utilizes magnesium and ATP; also involved in conversion of acetate to aceyl-CoA YP_253130.1 hypothetical protein,similar to USPA, An ATP binding domain seen as a stand alone in USPA YP_253132.1 Xaa-Pro dipeptidase homolog YP_253133.1 catalyzes the opening and hydrolysis of the beta-lactam ring of beta-lactam antibiotics such as penicillins and cephalosporins YP_253134.1 similar to unknown protein YP_253135.1 similar to unknown protein YP_253136.1 similar to unknown protein YP_253138.1 malate dehydrogenase homolog YP_253139.1 catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer of AccA2D2 subunits YP_253140.1 catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer composed of two alpha (AccA) and two beta (AccD) subunits; one of the two catalytic subunits that can form the acetyl CoA carboxylase enzyme together with a carrier protein YP_253141.1 catalyzes the formation of D-fructose 1,6-bisphosphate from D-fructose 6-phosphate in glycolysis YP_253143.1 similar to unknown protein YP_253145.1 catalyzes the formation of citrate from acetyl-CoA and oxaloacetate YP_253146.1 Converts isocitrate to alpha ketoglutarate YP_253150.1 hypothetical protein, similar to formamidopyrimidine-DNA glycosylase YP_253151.1 catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; involved in coenzyme A biosynthesis YP_253152.1 no similarity YP_253154.1 similar to unknown protein YP_253156.1 Primosomal protein that may act to load helicase DnaC during DNA replication YP_253157.1 catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr) YP_253158.1 no similarity YP_253160.1 IF-3 has several functions that are required and promote translation initiation including; preventing association of 70S by binding to 30S; monitoring codon-anticodon interactions by promoting disassociation of fMet-tRNA(fMet) from initiation complexes formed on leaderless mRNAs or incorrectly bound noninitiatior tRNAs and complexes with noncanonical start sites; stimulates codon-anticodon interactions at P-site; involved in moving mRNA to the P-site; and in recycling subunits YP_253162.1 binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit YP_253163.1 similar to unknown protein YP_253164.1 similar to unknown protein YP_253165.1 Tig; RopA; peptidyl-prolyl cis/trans isomerase; promotes folding of newly synthesized proteins; binds ribosomal 50S subunit; forms a homodimer YP_253166.1 binds and unfolds substrates as part of the ClpXP protease YP_253167.1 truncated YP_253168.1 truncated YP_253169.1 binds guanine nucleotides; in Escherichia coli depletion results in defective cell division and filamentation; in Bacillus subtilis this gene is essential YP_253170.1 catalyzes the formation of glutamate-1-semialdehyde from glutamyl-tRNA(Glu) and NADPH; the second step of the pathway is catalyzed by glutamate-1-semialdehyde aminomutase which results in the formation of 5-aminolevulinic acid; functions in porphyrin (tetrapyrroles) biosynthesis; the crystal structure showed a C-terminal dimerization domain that appears to be absent in Chlamydial proteins YP_253172.1 transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis YP_253174.1 catalyzes the formation of porphobilinogen from 5-aminolevulinate YP_253175.1 Converts (S)-4-amino-5-oxopentanoate to 5-aminolevulinate during the porphyrin biosynthesis pathway YP_253176.1 similar to unknown protein YP_253178.1 valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain YP_253180.1 hypothetical protein, similar to type IV prepilin peptidase YP_253181.1 hypothetical protein, similar to DNA repair protein YP_253182.1 similar to unknown protein YP_253183.1 similar to unknown protein YP_253184.1 similar to unknown protein YP_253185.1 similar to unknown protein YP_253186.1 in some organisms this protein is a transmembrane protein while in others it is periplasmic; involved in some organisms with other components of the MreBCD complex and with penicillin binding proteins in the periplasm or cell wall YP_253187.1 hypothetical protein, similar to cell shape determinant mreD YP_253189.1 similar to unknown protein YP_253190.1 involved in the peptidyltransferase reaction during translation YP_253191.1 no similarity YP_253192.1 essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication YP_253193.1 hypothetical protein, similar to chorismate mutase YP_253194.1 plays an essential role in ATP-dependent branch migration of the Holliday junction YP_253195.1 promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration YP_253196.1 Synthesizes oQ from preQ1 in a single S-adenosylmethionine-requiring step YP_253197.1 Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr) YP_253198.1 hypothetical protein, similar to protein translocase subunit YajC YP_253199.1 part of the preprotein secretory system; forms a complex with protein YajC; SecDFyajC stimulates the proton motive force-driven protein translocation, seems to modulate the cycling of SecA by stabilizing its membrane-inserted state and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; in some organisms, such as Bacillus subtilis, SecD is fused to SecF YP_253200.1 hypothetical protein, similar to single-strand DNA-specific exonuclease YP_253201.1 catalyzes a salvage reaction resulting in the formation of AMP which is metabolically less costly than a de novo synthesis YP_253203.1 hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr); possible defense mechanism against a harmful effect of D-tyrosine YP_253205.1 catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG YP_253206.1 catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes YP_253207.1 hypothetical protein, similar to ThiF family protein YP_253208.1 hypothetical protein, similar to ATPase family associated with various cellular activities YP_253209.1 hypothetical protein, similar to transcriptional regulator YP_253210.1 similar to unknown protein YP_253211.1 hypothetical protein, similar to alkanal monooxygenase alpha chain YP_253212.1 hypothetical protein, similar to aminotransferase class-V YP_253213.1 catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs YP_253214.1 similar to unknown protein YP_253215.1 hypothetical protein, similar to exodeoxyribonuclease V YP_253216.1 Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_253217.1 similar to unknown protein YP_253218.1 similar to RuvC resolvase with substantial differences; NMR structural information suggests this protein is monomeric; unknown cellular function YP_253219.1 similar to unknown protein YP_253220.1 hypothetical protein, similar to caffeoyl-CoA O-methyltransferase YP_253221.1 hypothetical protein, similar to protease YP_253222.1 hypothetical protein, similar to protease YP_253223.1 functions in pyrimidine salvage; pyrimidine ribonucleoside kinase; phosphorylates nucleosides or dinucleosides to make UMP or CMP using ATP or GTP as the donor YP_253224.1 necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus YP_253225.1 hypothetical protein, similar to allophanate hydrolase subunit 1 YP_253226.1 hypothetical protein, similar to Urea carboxylase YP_253227.1 hypothetical protein, similar to acetyl-CoA carboxylase (biotin carboxyl carrier subunit), accB homolog YP_253228.1 hypothetical protein, similar to acetyl-CoA carboxylase YP_253229.1 hypothetical protein, similar to lactam utilization-related protein YP_253230.1 hypothetical protein, similar to branched chain amino acids transporter YP_253232.1 hypothetical protein, similar to haloacid dehalogenase-like hydrolase YP_253233.1 in Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis YP_253235.1 hypothetical protein, similar to dihydrodipicolinate reductase YP_253236.1 hypothetical protein, similar to nicotinate mononucleotide adenylyltransferase YP_253237.1 hypothetical protein, similar to HD domain YP_253238.1 similar to unknown protein YP_253239.1 hypothetical protein, similar to ubiE/COQ5 methyltransferase family YP_253240.1 hypothetical protein, similar to late competence operon protein required for DNA binding and uptake ComEA YP_253242.1 hypothetical protein, similar to ComEC late competence protein 3 (comE operon) YP_253243.1 required for the assembly and function of the DNAX complex which is required for the assembly of the beta subunit onto primed DNA YP_253244.1 no similarity YP_253246.1 binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase YP_253247.1 binds to the ribosome on the universally-conserved alpha-sarcin loop YP_253248.1 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III YP_253250.1 with DnaK and DnaJ acts in response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins; may act as a thermosensor YP_253251.1 heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria YP_253252.1 chaperone Hsp40; co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion YP_253253.1 methylates ribosomal protein L11 at multiple amino acid positions; mutations of these genes in Escherichia coli or Thermus thermophilus has no apparent phenotype YP_253254.1 in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA; cells lacking this function can grow, but are outcompeted by wild-type; SAM-dependent m(3)U1498 methyltransferase YP_253255.1 similar to unknown protein YP_253256.1 a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA YP_253257.1 similar to unknown protein YP_253258.1 similar to unknown protein YP_253259.1 similar to unknown protein YP_253260.1 phosphate starvation-induced protein phoH homolog YP_253261.1 similar to unknown protein YP_253262.1 hypothetical protein, similar to diacylglycerol kinase YP_253264.2 Era; Escherichia coli Ras-like protein; Bex; Bacillus Era-complementing segment; essential protein in Escherichia coli that is involved in many cellular processes; GTPase; binds the cell membrane through apparent C-terminal domain; mutants are arrested during the cell cycle; Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome YP_253265.1 hypothetical protein, similar to DNA repair protein RecO YP_253266.1 Catalyzes a two-step reaction, first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_253267.1 similar to unknown protein YP_253268.1 similar to unknown protein YP_253270.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; primary sigma factor of bacterium YP_253271.1 similar to unknown protein YP_253272.1 similar to unknown protein YP_253273.1 hypothetical protein, similar to ATP-dependent RNA helicase YP_253274.1 Assists in DNA repair by cleaving phosphodiester bonds at apurinic or apyrimidinic sties to produce new 5' ends that are base-free deoxyribose 5-phosphate residues YP_253275.1 ABC transporter ATP-binding protein MreA homolog YP_253276.1 ABC transporter peamease protein MreB homolog YP_253280.1 in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif YP_253281.1 hypothetical protein, similar to 5-formyltetrahydrofolate cyclo-ligase family protein YP_253282.1 similar to unknown protein YP_253283.1 similar to unknown protein YP_253285.1 similar to unknown protein YP_253286.1 hypothetical protein, similar to metallo-beta-lactamase superfamily protein YP_253287.1 hypothetical protein, similar to late competence protein comGA YP_253288.1 hypothetical protein, similar to DNA transport machinery protein comGB YP_253290.1 hypothetical protein, similar to comG operon protein 4 (comGD) YP_253291.1 similar to unknown protein YP_253292.1 hypothetical protein, similar to competence protein ComYC YP_253293.1 hypothetical protein, similar to shikimate kinase (SK) YP_253294.1 catalyzes the transfer of a methylene carbon from the methylamine-loaded GcvH protein to tetrahydrofolate, causing the release of ammonia and the generation of reduced GcvH protein YP_253295.1 acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine; forms a heterodimer with subunit 2 to form the P protein YP_253296.1 acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine; forms a heterodimer with subunit 1 to form the P protein YP_253297.1 hypothetical protein, similar to rhodanese Homology Domain YP_253298.1 hypothetical protein, similar to lipoate protein ligase YP_253299.1 similar to unknown protein YP_253300.1 similar to unknown protein YP_253302.1 Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA YP_253304.1 an AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism YP_253305.1 similar to unknown protein YP_253306.1 Regulates rRNA biosynthesis by transcriptional antitermination YP_253307.1 bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides YP_253308.1 catalyzes the bidirectional exonucleolytic cleavage of DNA YP_253310.1 regulates arginine biosynthesis when complexed with arginine by binding at site that overlap the promotors of the arginine biosynthesis genes YP_253316.1 similar to unknown protein YP_253317.1 similar to unknown protein YP_253318.1 truncated YP_253319.1 no similarity YP_253320.1 hypothetical protein, similar to tripeptidase YP_253321.1 catalyzes the formation of D-ribulose 5-phosphate from 6-phospho-D-gluconate YP_253322.1 hypothetical protein, similar to maltose operon transcriptional repressor YP_253324.1 similar to unknown protein YP_253325.1 transcription regulator AraC/XylS family homolog YP_253326.1 catalyzes the formation of D-glucono-1,5-lactone 6-phosphate from D-glucose 6-phosphate YP_253327.1 hypothetical protein, similar to metallo-beta-lactamase superfamily YP_253328.1 hypothetical protein, similar to pyrroline-5-carboxylate reductase YP_253329.1 hypothetical protein, similar to oxidoreductase YP_253330.1 no similarity YP_253331.1 hypothetical protein, similar to aldo/keto reductase family YP_253333.1 ferric uptake regulator homolog YP_253335.1 similar to unknown protein YP_253336.1 similar to unknown protein YP_253337.1 similar to unknown protein YP_253341.1 no similarity YP_253342.1 hypothetical protein, similar to riboflavin transporter YP_253344.1 similar to unknown protein YP_253345.1 hypothetical protein, similar to ATP-dependent DNA helicase recQ YP_253347.1 hypothetical protein, similar to thioredoxin reductase homolog YP_253349.1 Catalyzes the formation of (d)CDP from ATP and (d)CMP YP_253350.1 in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins YP_253351.1 EngA; essential Neisserial GTPase; synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains YP_253352.1 catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate YP_253354.1 truncated YP_253355.1 truncated YP_253356.1 no similarity YP_253357.1 hypothetical protein, similar to component A of hexaprenyl diphosphate synthase YP_253358.1 Catalyzes the carbon methylation reaction in the biosynthesis of ubiquinone YP_253360.1 catalyzes the formation of nucleoside triphosphate from ATP and nucleoside diphosphate YP_253361.1 catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis YP_253362.1 catalyzes the formation of 3-dehydroquinate from 3-deoxy-arabino-heptulonate 7-phosphate; functions in aromatic amino acid biosynthesis YP_253363.1 catalyzes the formation of 5-O-(1-carboxyvinyl)-3-phosphoshikimate from phosphoenolpyruvate and 3-phosphoshikimate in tryptophan biosynthesis YP_253364.1 similar to unknown protein YP_253365.1 similar to unknown protein YP_253366.1 similar to unknown protein YP_253367.1 similar to unknown protein YP_253368.1 similar to unknown protein YP_253369.1 hypothetical protein, similar to lipopolysaccharide biosynthesis-related pr homolog YP_253370.1 catalyzes the addition and repair of the 3'-terminal CCA sequence in tRNA; these proteins belong to the CCA-adding enzyme subfamily 2 which does not have phosphohydrolase activity YP_253371.1 hypothetical protein, similar to bifunctional biotin ligase/biotin operon repressor YP_253373.1 catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_253376.1 similar to unknown protein YP_253378.1 functions in homologous recombination, DNA repair, and chromosome segregation; binds preferentially to three- and four-stranded DNA intermediates; introduces specific nick sites in four-stranded DNA substrates; functions similarly to Escherichia coli RuvC YP_253379.1 similar to unknown protein YP_253380.1 similar to unknown protein YP_253381.1 hypothetical protein, similar to cell division protein DivIVA YP_253382.1 similar to unknown protein YP_253383.1 similar to unknown protein YP_253384.1 hypothetical protein, similar to GTPase of unknown function YP_253385.1 hypothetical protein, similar to 5'-3' exonuclease YP_253386.1 hypothetical protein, similar to hemagglutinin/hemolysin-related protein YP_253387.1 no similarity YP_253388.1 hypothetical protein,similar to cell wall enzyme EbsB YP_253389.1 hypothetical protein, similar to membrane transporter protein YP_253390.1 similar to unknown protein YP_253391.1 similar to unknown protein YP_253392.1 similar to unknown protein YP_253393.1 similar to unknown protein YP_253394.1 ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived YP_253396.1 similar to unknown protein YP_253397.1 this stereospecific enzymes reduces the S isomer of methionine sulfoxide while MsrB reduces the R form; provides protection against oxidative stress YP_253398.1 this stereospecific enzymes reduces the R isomer of methionine sulfoxide while MsrA reduces the S form; provides protection against oxidative stress YP_253400.1 similar to unknown protein YP_253402.1 hypothetical protein, similar to acetyltransferase YP_253403.1 UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; involved in cell wall formation; inner membrane-associated; last step of peptidoglycan synthesis YP_253404.1 similar to unknown protein YP_253405.1 hypothetical protein, similar to response regulator ArlR [truncated] YP_253407.1 SucA; E1 component of the oxoglutarate dehydrogenase complex which catalyzes the formation of succinyl-CoA from 2-oxoglutarate; SucA catalyzes the reaction of 2-oxoglutarate with dihydrolipoamide succinyltransferase-lipoate to form dihydrolipoamide succinyltransferase-succinyldihydrolipoate and carbon dioxide YP_253408.1 component of 2-oxoglutarate dehydrogenase complex; catalyzes the transfer of succinyl coenzyme A to form succinyl CoA as part of the conversion of 2-oxoglutarate to succinyl-CoA YP_253409.1 no similarity YP_253410.1 no similarity YP_253412.1 no similarity YP_253413.1 ABC transporter homolog YP_253414.1 similar to unknown protein YP_253415.1 hypothetical protein, similar to nitric-oxide reductase YP_253416.1 similar to unknown protein YP_253418.1 no similarity YP_253420.1 hypothetical protein, similar to tellurite resistance protein YP_253421.1 hypothetical protein, similar to 5-bromo-4-chloroindolyl phosphate hydrolysis protein xpaC YP_253422.1 catalyzes the hydrolysis of acylphosphate YP_253423.1 hypothetical protein, similar to DNA binding protein YP_253430.1 catalyzes the reduction of 2,3-dihydrodipicolinate to 2,3,4,5-tetrahydrodipicolinate in lysine and diaminopimelate biosynthesis YP_253431.1 catalyzes the formation of dihydrodipicolinate from L-aspartate 4-semialdehyde and pyruvate in lysine and diaminopimelate biosynthesis YP_253433.1 catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP, in Bacillus, lysine sensitive; regulated by response to starvation. YP_253434.1 no similarity YP_253435.1 ABC transporter homolog YP_253436.1 similar to unknown protein YP_253438.1 hypothetical protein, similar to phosphate ABC transporter YP_253439.1 hypothetical protein, similar to phosphate ABC transporter YP_253440.1 ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation YP_253441.1 hypothetical protein, similar to negative regulator PhoU YP_253442.1 hypothetical protein, similar to oligoendopeptidase YP_253444.1 hypothetical protein, similar to lipoprotein YP_253445.1 similar to unknown protein YP_253449.1 no similarity YP_253450.1 no similarity YP_253451.1 catalyzes the formation of indole and glyceraldehyde 3-phosphate from indoleglycerol phosphate in tryptophan biosynthesis YP_253452.1 catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate YP_253453.1 catalyzes the formation of 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate from N-(5-phospho-beta-D-ribosyl)-anthranilate in tryptophan biosynthesis YP_253454.1 involved in tryptophan biosynthesis; amino acid biosynthesis; converts 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate to C(1)-(3-indolyl)-glycerol 3-phosphate and carbon dioxide and water YP_253455.1 Catalyzes the conversion of N-(5-phospho-D-ribosyl)-anthranilate and diphosphate to anthranilate and 5-phospho-alpha-D-ribose 1-diphosphate YP_253457.1 with component II, the glutamine amidotransferase, catalyzes the formation of anthranilate from chorismate and glutamine YP_253458.1 hypothetical protein, similar to glucanase YP_253459.1 catalyzes the formation of 4-hydroxyphenylpyruvate from prephenate YP_253460.1 hypothetical protein, similar to DNA-damage repair protein YP_253463.1 this stereospecific enzymes reduces the S isomer of methionine sulfoxide while MsrB reduces the R form; provides protection against oxidative stress YP_253465.1 similar to unknown protein YP_253468.1 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling YP_253469.1 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling YP_253470.1 similar to unknown protein YP_253471.1 similar to unknown protein YP_253472.1 similar to unknown protein YP_253473.1 Catalyzes the conversion of citrate to isocitrate YP_253475.1 forms homopentamer; channel that opens in response to pressure or hypoosmotic shock YP_253476.1 hypothetical protein, similar to exonuclease SbcC YP_253477.1 hypothetical protein, similar to exonuclease SbcD YP_253478.1 similar to unknown protein YP_253479.1 similar to unknown protein YP_253481.1 similar to unknown protein YP_253482.1 similar to unknown protein YP_253483.1 Represses a number of genes involved in the response to DNA damage YP_253484.1 similar to unknown protein YP_253485.1 hypothetical protein, similar to GMP reductase YP_253486.1 located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group do not appear to have the zinc-binding motif YP_253487.1 in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif YP_253490.1 similar to unknown protein YP_253491.1 similar to unknown protein YP_253492.1 catalyzes the formation of O-phospho-L-homoserine from L-homoserine in threonine biosynthesis from asparate YP_253493.1 catalyzes the formation of L-threonine from O-phospho-L-homoserine YP_253494.1 catalyzes the formation of L-aspartate 4-semialdehyde from L-homoserine YP_253495.1 catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP; lysine and threonine sensitive YP_253496.1 similar to unknown protein YP_253497.1 similar to unknown protein YP_253499.1 similar to unknown protein YP_253500.1 no similarity YP_253501.1 hypothetical protein, similar to two-component response regulator YP_253502.1 hypothetical protein, similar to two-component sensor histidine kinase YP_253503.1 hypothetical protein, similar to ABC transporter integral membrane protein YP_253504.1 ABC transporter (ATP-binding protein) homolog YP_253505.1 cardiolipin synthetase homolog YP_253506.1 similar to unknown protein YP_253507.1 similar to unknown protein YP_253508.1 no similarity YP_253509.1 no similarity YP_253510.1 no similarity YP_253511.1 no similarity YP_253512.1 similar to unknown protein YP_253513.1 similar to unknown protein YP_253514.1 similar to unknown protein YP_253517.1 hypothetical protein, similar to aluminum resistance protein YP_253518.1 hypothetical protein, similar to GTP-binding protein proteinase modulator homolog ynbA YP_253520.1 hypothetical protein, similar to host factor-1 YP_253521.1 IPP transferase; isopentenyltransferase; involved in tRNA modification; in Escherichia coli this enzyme catalyzes the addition of a delta2-isopentenyl group from dimethylallyl diphosphate to the N6-nitrogen of adenosine adjacent to the anticodon of tRNA species that read codons starting with uracil; further tRNA modifications may occur; mutations in miaA result in defects in translation efficiency and fidelity YP_253522.1 hypothetical protein, similar to lysophospholipase YP_253524.1 Converts glycerol and ADP to glycerol-3-phosphate and ADP YP_253531.1 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. Promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex YP_253532.1 This protein performs the mismatch recognition step during the DNA repair process YP_253533.1 similar to unknown protein YP_253534.1 similar to unknown protein YP_253535.1 catalyzes the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine from N6-(dimethylallyl)adenosine (i(6)A) YP_253536.1 similar to unknown protein YP_253537.1 hypothetical protein, similar to phage-related replication protein YP_253538.1 catalyzes the coenzyme A dependent formation of succinyl-CoA from 2-oxoglutarate and ferredoxin YP_253539.1 hypothetical protein, similar to 2-oxoacid ferredoxin oxidoreductase, alpha subunit YP_253540.1 similar to unknown protein YP_253541.1 similar to unknown protein YP_253542.1 protein from Staphylococcus aureus has phosphodiesterase activity against 2'-3'-cAMP and 2'-3'-cGMP YP_253543.1 catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs YP_253546.1 similar to unknown protein YP_253547.1 similar to unknown protein YP_253548.1 hypothetical protein, similar to 3-oxoacyl- acyl-carrier protein reductase homolog ymfI YP_253549.1 hypothetical protein, similar to precessing proteinase YP_253550.1 hypothetical protein, similar to processing proteinase homolog YP_253551.1 hypothetical protein, similar to transcription regulator GntR family YP_253552.1 sporulation-related protein SpoIIIE homologue YP_253553.1 similar to unknown protein YP_253555.1 primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence YP_253557.1 catalyzes isomerization of specific uridines in RNA to pseudouridine; responsible for residues in T loops of many tRNAs YP_253559.1 associates with free 30S ribosomal subunits; essential for efficient processing of 16S rRNA; in Escherichia coli rbfA is induced by cold shock YP_253560.1 Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex YP_253561.1 hypothetical protein, similar to ribosomal protein L7AE family YP_253562.1 similar to unknown protein YP_253563.1 modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination YP_253564.1 in Streptococcus pneumoniae this gene was found to be essential; structure determination of the Streptococcus protein shows that it is similar to a number of other proteins YP_253565.1 catalyzes DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time; required for leading strand synthesis; PolC exhibits 3' to 5' exonuclease activity YP_253566.1 catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro) YP_253567.1 similar to unknown protein YP_253569.1 catalyzes the formation of undecaprenyl pyrophosphate from isopentenyl pyrophosphate YP_253570.1 Rrf; Frr; ribosome-recycling factor; release factor 4; RF4; recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G; A GTPase-dependent process results in release of 50S from 70S; inhibited by release factor RF-1; essential for viability; structurally similar to tRNAs YP_253571.1 Catalyzes the phosphorylation of UMP to UDP YP_253572.1 EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu YP_253573.1 one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit YP_253574.1 CodY; DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase (By similarity). It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor YP_253575.1 heat shock protein involved in degradation of misfolded proteins YP_253576.1 heat shock protein involved in degradation of misfolded proteins YP_253577.1 site-specific recombinase XerC homolog YP_253578.1 TrmFO; Gid; glucose-inhibited division protein; similar to GidA; the gene from Bacillus subtilis encodes a tRNA-methyltransferase that utilizes folate as the carbon donor and bound flavin as reductant; modifies tRNA at position 54 (uridine) of the T-psi loop to form a C5-methyluridine YP_253579.1 catalyzes the ATP-dependent breakage of single-stranded DNA followed by passage and rejoining, maintains net negative superhelicity YP_253580.1 hypothetical protein, similar to DNA processing Smf protein YP_253582.1 Catalyzes the only substrate-level phosphorylation in the TCA cycle YP_253583.1 catalyzes the interconversion of succinyl-CoA and succinate YP_253584.1 RNH2; RNase HII; binds manganese; endonuclease which specifically degrades the RNA of RNA-DNA hybrids YP_253585.1 essential GTPase; functions in ribosome assembly; binds a unique part of the 23S rRNA; interacts with ribosomal protein L25(Ctc) YP_253586.1 similar to unknown protein YP_253587.1 similar to unknown protein YP_253588.1 this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site YP_253589.1 methylates guanosine-37 in various tRNAs; uses S-adenosyl-L-methionine to transfer methyl group to tRNA YP_253590.1 Essential for efficient processing of 16S rRNA YP_253591.1 binds to lower part of 30S body where it stabilizes two domains; required for efficient assembly of 30S; in Escherichia coli this protein has nuclease activity YP_253592.1 signal recognition particle homolog YP_253593.1 similar to unknown protein YP_253594.1 signal recognition particle and cell-dovision protein FtsY homolog YP_253596.1 cytoplasmic enzyme involved in processing rRNA and some mRNAs; substrates typically have dsRNA regions; forms a homodimer; have N-terminal nuclease and C-terminal RNA-binding domains; requires magnesium as preferred ion for activity YP_253597.1 carries the fatty acid chain in fatty acid biosynthesis YP_253600.1 involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsY YP_253601.1 negative regulator of genes involved in fatty acid and phospholipid biosynthesis for gram positive bacteria YP_253602.1 catalyzes branch migration in Holliday junction intermediates YP_253603.1 hypothetical protein, similar to staphylococcal nuclease YP_253604.1 similar to unknown protein YP_253605.1 similar to unknown protein YP_253606.1 required for 70S ribosome assembly YP_253607.1 hypothetical protein, similar to thiamin pyrophosphokinase YP_253609.1 similar to unknown protein YP_253610.1 hypothetical protein, similar to protein kinase YP_253611.1 hypothetical protein, similar to PP2C protein phosphatase YP_253612.1 23S rRNA m2A2503 methyltransferase; methylates the C2 position of the A2530 nucleotide in 23S rRNA; may be involved in antibiotic resistance YP_253613.1 hypothetical protein, similar to RNA-binding Sun protein YP_253615.1 cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+) YP_253616.1 similar to unknown protein YP_253618.1 pantothenate metabolism flavoprotein homolog YP_253619.1 Promotes RNA polymerase assembly; latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits YP_253620.1 Essential for recycling GMP and indirectly, cGMP YP_253621.1 hypothetical protein, similar to fibronectin/fibrinogen-binding protein YP_253622.1 similar to unknown protein YP_253623.1 similar to unknown protein YP_253624.1 involved in fifth step of pyrimidine biosynthesis; converts orotidine 5'-phosphate and diphosphate to orotate and 5-phospho-alpha-D-ribose 1-diphosphate YP_253625.1 type 1 subfamily; involved in last step of pyrimidine biosynthesis; converts orotidine 5'-phosphate to UMP and carbon dioxide; OMP decarboxylase; OMPDCase; OMPdecase YP_253626.1 four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate; CarB is responsible for the amidotransferase activity YP_253627.1 catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers YP_253628.1 catalyzes the formation of N-carbamoyl-L-aspartate from (S)-dihydroorotate in pyrimidine biosynthesis YP_253629.1 catalyzes the transfer of the carbamoyl moiety from carbamoyl phosphate to L- aspartate in pyrimidine biosynthesis YP_253631.1 regulates pyrimidine biosynthesis by binding to the mRNA of the pyr genes, also has been shown to have uracil phosphoribosyltransferase activity YP_253632.1 hypothetical protein, similar to ribosomal large subunit pseudouridine synthase D YP_253633.1 lipoprotein signal peptidase; integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis YP_253634.1 hypothetical protein, similar to secretory antigen SsaA YP_253635.1 similar to unknown protein YP_253636.1 similar to unknown protein YP_253637.1 IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase family type 1 subfamily; some organisms carry two different copies of this enzyme YP_253638.1 hypothetical protein, similar to cell-division initiation protein DivIVA YP_253639.1 hypothetical protein, similar to cell-division protein YP_253640.1 similar to unknown protein YP_253641.1 similar to unknown protein YP_253642.1 similar to unknown protein YP_253643.1 similar to unknown protein YP_253644.1 GTPase; similar structure to tubulin; forms ring-shaped polymers at the site of cell division; other proteins such as FtsA, ZipA, and ZapA, interact with and regulate FtsZ function YP_253646.1 cell division protein, FtsQ homolog YP_253647.1 UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation YP_253648.1 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan YP_253651.1 similar to unknown protein YP_253652.1 MraZ; UPF0040; crystal structure shows similarity to AbrB YP_253653.1 similar to unknown protein YP_253654.1 hypothetical protein, similar to acetyltransferase, GNAT family YP_253655.1 hypothetical protein, similar to haloacid dehalogenase-like hydrolase YP_253656.1 antibacterial protein 1 homolog YP_253657.1 antibacterial protein 2 homolog YP_253658.1 antibacterial protein 3 homolog YP_253659.1 antibacterial protein 2 homolog YP_253660.1 antibacterial protein 3 homolog YP_253661.1 no similarity YP_253662.1 no similarity YP_253665.1 no similarity YP_253666.1 hypothetical protein, similar to phage-related protein YP_253667.1 no similarity YP_253668.1 no similarity YP_253669.1 no similarity YP_253670.1 no similarity YP_253671.1 hypothetical protein, similar to phage-related protein YP_253672.1 no similarity YP_253673.1 no similarity YP_253680.1 similar to unknown protein YP_253681.1 no similarity YP_253682.1 similar to unknown protein YP_253683.1 similar to unknown protein YP_253684.1 similar to unknown protein YP_253685.1 similar to unknown protein YP_253686.1 similar to unknown protein YP_253687.1 similar to unknown protein YP_253688.1 hypothetical protein, similar to ClpP-like protease YP_253689.1 similar to unknown protein YP_253690.1 hypothetical protein, similar to phage terminase YP_253691.1 similar to unknown protein YP_253692.1 similar to unknown protein YP_253693.1 hypothetical protein, similar to orf 61 from Staphylococcus aureus phage phiPVL YP_253694.1 hypothetical protein, similar to phage hilicase YP_253695.1 hypothetical protein, similar to phage-related protein YP_253696.1 similar to unknown protein YP_253697.1 hypothetical protein, similar to ofr60 from Staphylococcus aureus phage phiPVL YP_253698.1 hypothetical protein, similar to int gene activator RinB YP_253699.1 no similarity YP_253700.1 hypothetical protein, similar to ofr55 from Staphylococcus aureus phage phiPVL YP_253701.1 no similarity YP_253702.1 no similarity YP_253703.1 hypothetical protein, similar to ArpR YP_253704.1 no similarity YP_253705.1 no similarity YP_253706.1 hypothetical protein, similar to phage-related protein YP_253708.1 hypothetical protein, similar to phage-related protein YP_253709.1 hypothetical protein, similar to phage-related protein YP_253710.1 no similarity YP_253711.1 hypothetical protein, similar to phi PVL ORF 38 YP_253712.1 similar to unknown protein YP_253713.1 no similarity YP_253714.1 no similarity YP_253715.1 hypothetical protein, similar to ORF2 from Streptococcus thermophilus bacteriophage 7201 YP_253716.1 hypothetical protein, similar to orf 11 from Staphylococcus aureus prophage phiPV83 YP_253717.1 no similarity YP_253718.1 hypothetical protein, similar to phage anti-repressor YP_253719.1 similar to unknown protein YP_253720.1 hypothetical protein, similar to transcriptional regulator, Cro/CI family YP_253721.1 no similarity YP_253722.1 similar to unknown protein YP_253724.1 similar to unknown protein YP_253725.1 hydrolyzes non-standard nucleotides such as xanthine and inosine YP_253726.1 converts L-glutamate to D-glutamate, a component of peptidoglycan YP_253727.1 part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; the catalytic subunits are similar to fumarate reductase YP_253728.1 part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol YP_253730.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision YP_253732.1 MutS2; MutS-II; involved in blocking homologous and homeologous recombination; has ATPase activity stimulated by recombination intermediates; inhibits DNA strand exchange YP_253734.1 similar to unknown protein YP_253735.1 similar to unknown protein YP_253736.1 An endonuclease that specifically degrades the RNA strand of RNA-DNA hybrids YP_253737.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily YP_253738.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily YP_253739.1 hypothetical protein, similar to rRNA methylase YP_253740.1 some L32 proteins have zinc finger motifs consisting of CXXC while others do not YP_253741.1 similar to unknown protein YP_253742.1 similar to unknown protein YP_253743.1 Catalyzes the conversion of ATP and pantetheine 4'-phosphate to diphosphate and 3'-dephospho-coA YP_253744.1 similar to unknown protein YP_253745.1 similar to unknown protein YP_253746.1 similar to unknown protein YP_253747.1 hypothetical protein, similar to glycerophosphoryl diester phosphodiesterase YP_253748.1 similar to unknown protein YP_253749.1 similar to unknown protein YP_253750.1 similar to unknown protein YP_253751.1 converts protoheme IX and farnesyl diphosphate to heme O YP_253753.1 biotin-containing enzyme that catalyzes a two step carboxylation of pyruvate to oxaloacetate YP_253754.1 similar to unknown protein YP_253755.1 depletion of this protein in Bacillus subtilis results in defects in cell morphology; crystal structure of Staphylococcus protein shows homodimer; ligand binding protein YP_253756.1 similar to unknown protein YP_253757.1 similar to unknown protein YP_253758.1 GTP-binding elongation factor homologue YP_253759.1 similar to unknown protein YP_253760.1 myo-inositol-1(or 4)-monophosphatase homolog YP_253761.1 similar to unknown protein YP_253763.1 similar to unknown protein YP_253764.1 similar to unknown protein YP_253769.1 hypothetical protein, similar to transcriptional regulator, Cro/CI family YP_253770.1 similar to unknown protein YP_253771.1 E3 component of pyruvate complex; catalyzes the oxidation of dihydrolipoamide to lipoamide YP_253775.1 similar to unknown protein YP_253776.1 cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+) YP_253777.1 similar to unknown protein YP_253778.1 similar to unknown protein YP_253779.1 no similarity YP_253780.1 truncated YP_253781.1 similar to unknown protein YP_253782.1 hypothetical protein, similar to potassium uptake protein YP_253785.1 similar to unknown protein YP_253786.1 no similarity YP_253787.1 truncated YP_253788.1 truncated YP_253791.1 similar to unknown protein YP_253792.1 similar to unknown protein YP_253793.1 similar to unknown protein YP_253794.1 similar to unknown protein YP_253795.1 similar to unknown protein YP_253796.1 hypothetical protein, similar to cation ABC transporter YP_253797.1 similar to unknown protein YP_253798.1 catalyzes the formation of N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-D-ribosylamine and glycine in purine biosynthesis YP_253799.1 involved in de novo purine biosynthesis YP_253801.1 catalyzes the formation of 1-(5-phosphoribosyl)-5-aminoimidazole from 2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in purine biosynthesis YP_253802.1 Catalyzes first step of the de novo purine nucleotide biosynthetic pathway YP_253803.1 catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis YP_253804.1 catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis YP_253805.1 hypothetical protein, similar to phosphoribosylformylglycinamidine (FGAM) synthase, PurS subunit YP_253806.1 catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis; SAICAR synthase YP_253807.1 With PurE catalyzes the conversion of aminoimidazole ribonucleotide to carboxyaminoimidazole ribonucleotide in the de novo purine nucleotide biosynthetic pathway YP_253809.1 catalyzes the formation of 5,10-methenyltetrahydrofolate from 5,10-methylenetetrahydrofolate and subsequent formation of 10-formyltetrahydrofolate from 5,10-methenyltetrahydrofolate YP_253810.1 no similarity YP_253811.1 truncated YP_253812.1 no similarity YP_253814.1 hypothetical protein, similar to flavohemoprotein YP_253815.1 hypothetical protein, similar to chitinase B YP_253816.1 hypothetical protein, similar to quinol oxidase polypeptide II QoxA YP_253819.1 hypothetical protein, similar to quinol oxidase polypeptide IV QoxD YP_253820.1 catalyzes the hydrolysis of both purine and pyrimidine ribonucleosides YP_253823.1 similar to unknown protein YP_253824.1 similar to unknown protein YP_253825.1 hypothetical protein, similar to acetyl transferase YP_253829.1 similar to unknown protein YP_253830.1 similar to unknown protein YP_253831.1 HisC romatic amino acid aminotransferase HisC homolog YP_253832.1 catalyzes the formation of 1,4-dihydroxy-2-naphthoate from O-succinylbenzoyl-CoA YP_253833.1 hypothetical protein, similar to prolyl aminopeptidase YP_253835.1 hypothetical protein, similar to menaquinone-specific isochorismate synthase YP_253836.1 catalyzes the formation of dimethylmenaquinone from 1,4-dihydroxy-2-naphthoate and octaprenyl diphosphate YP_253837.1 similar to unknown protein YP_253838.1 similar to unknown protein YP_253839.1 similar to unknown protein YP_253840.1 similar to unknown protein YP_253841.1 hypothetical protein, similar to competence transcription factor YP_253843.1 similar to unknown protein YP_253844.1 no similarity YP_253845.1 similar to unknown protein YP_253847.1 similar to unknown protein YP_253848.1 similar to unknown protein YP_253849.1 hypothetical protein, similar to nucleotidase YP_253850.1 hypothetical protein, similar to Na+-transporting ATP synthase YP_253851.1 hypothetical protein, similar to serine protease HtrA YP_253852.1 toxic anion resistance protein homologue YP_253853.1 no similarity YP_253854.1 stimulates the release of release factors 1 and 2 from the ribosome after hydrolysis of the ester bond in peptidyl-tRNA has occurred; GDP/GTP-binding protein YP_253855.1 no similarity YP_253856.1 involved in cell wall formation; peptidoglycan synthesis; cytoplasmic enzyme; catalyzes the addition of lysine to UDP-N-acetylmuramoyl-L-alanyl-D-glutamate forming UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysine YP_253857.1 processive; catalyzes the formation of mono-, di- and tri-glucosyldiacylglycerol by the progressive transfer of glucosyl residues to diacylglycerol; involved in the formation of membrane glycolipids YP_253858.1 hypothetical protein, similar to multidrug resistance protein-related protein YP_253859.1 similar to 2'-5' RNA ligase YP_253860.1 similar to unknown protein YP_253861.1 similar to unknown protein YP_253862.1 Catalyzes a key regulatory step in fatty acid biosynthesis YP_253863.1 Na+/H+ antiporter homologue YP_253864.1 hypothetical protein, similar to Mg2+ transporter YP_253866.1 catalyzes the phosphorylation of NAD to NADP YP_253868.1 similar to unknown protein YP_253869.1 similar to unknown protein YP_253870.1 hypothetical protein, similar to Protozoan/cyanobacterial globin YP_253871.1 similar to unknown protein YP_253873.1 hypothetical protein, similar to transcription factor YP_253875.1 enables recognition and targeting of proteins for proteolysis, involved in negative regulation of competence YP_253876.1 the anti-alpha factor Spx interacts with RNA polymerase alpha subunit C-terminal domain in a region that interacts with the sigma 70 subunit and may interfere with activation of promoters; in Bacillus subtilis this protein is a substrate for ClpXP protease; blocks transcription of the competence regulatory gene encoded by the srf operon; regulates a number of genes involved in thiol homeostasis including trxA and trxB; monomeric member of ArsC family of proteins; does not bind DNA; contains a disulfide bond between C10 and C13 which may sense disulfide stress YP_253877.1 catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_253878.1 no similarity YP_253879.1 truncated YP_253881.1 hypothetical protein, similar to peptide binding protein OppA YP_253884.1 hypothetical protein, similar to oligopeptide transport system permease protein OppC YP_253886.1 similar to unknown protein YP_253888.1 FabH; beta-ketoacyl-acyl carrier protein synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs YP_253889.1 similar to unknown protein YP_253890.1 ClpB chaperone homologue YP_253891.1 hypothetical protein, similar to lipopolysaccharide modification acyltransferase YP_253892.1 similar to unknown protein YP_253893.1 similar to unknown protein YP_253894.1 NADPH-dependent; catalyzes the reduction of coenzyme A disulfide YP_253895.1 similar to unknown protein YP_253896.1 hypothetical protein, partially similar to PTS enzyme II glucose-specific factor II component YP_253897.1 hypothetical protein, similar to 5-oxo-1,2,5-tricarboxilic-3-penten acid decarboxylase YP_253898.1 hypothetical protein, similar to ATP-dependent nuclease subunit A YP_253899.1 hypothetical protein, similar to ATP-dependent nuclease subunit B YP_253902.1 similar to unknown protein YP_253903.1 functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis; catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate; member of PGI family YP_253904.1 catalyzes the formation of 2-N(omega)-(L-arginino)succinate from L-citrulline and L-aspartate in arginine biosynthesis, AMP-forming YP_253905.1 catalyzes the formation of arginine from (N-L-arginino)succinate YP_253909.1 hypothetical protein, similar to NADH-dependent flavin oxidoreductase YP_253910.1 hypothetical protein, similar to polyribonucleotide nucleotidyltransferase YP_253911.1 no similarity YP_253913.1 hypothetical protein, similar to kinase-associated protein B YP_253914.1 subunit A of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali YP_253915.1 subunit B of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; in the case of S. meliloti it was proved to be involved specifically with K+ transport YP_253916.1 subunit C of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali YP_253917.1 subunit D of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; contains an oxidoreductase domain; catalyzes the transfer of electrons from NADH to ubiquinone YP_253918.1 subunit E of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali YP_253919.1 subunit F of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali YP_253920.1 subunit G of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali YP_253921.1 similar to unknown protein YP_253922.1 similar to unknown protein YP_253923.1 similar to unknown protein YP_253925.1 hypothetical protein, similar to NADH dehydrogenase YP_253926.1 similar to unknown protein YP_253927.1 similar to unknown protein YP_253928.1 hypothetical protein, similar to NADH dehydrogenase YP_253929.1 similar to unknown protein YP_253931.1 no similarity YP_253934.1 D-alanyl carrier protein subunit; involved in the incorporation of D-alanine into membrane-associated D-alanyl-lipoteichoic acid; D-alanyl carrier protein is the acceptor of activated D-alanine which it donates to a membrane acceptor(D-alanyl transferase) for incorporation into membrane lipoteichoic acid YP_253936.1 transfers D-alanine to the D-alanyl carrier protein during the incorporation of D-alanine into lipoteichoic acid YP_253937.1 hypothetical protein, similar to D-Ala-teichoic acid biosynthesis protein YP_253938.1 hypothetical protein, similar to glycerate dehydrogenase YP_253939.1 hypothetical protein, similar to N-acetyl-glucosamine catabolism homologue YP_253940.1 similar to unknown protein YP_253941.1 similar to unknown protein YP_253942.1 similar to unknown protein YP_253943.1 catalyzes the radical-mediated insertion of two sulfur atoms into an acyl carrier protein (ACP) bound to an octanoyl group to produce a lipoyl group YP_253944.1 similar to unknown protein YP_253945.1 similar to unknown protein YP_253946.1 similar to unknown protein YP_253947.1 hypothetical protein, similar to 2-nitropropane dioxygenase YP_253949.1 no similarity YP_253950.1 similar to unknown protein YP_253951.1 hypothetical protein, similar to nitrogen fixation protein NifU YP_253952.1 aminotransferase NifS homologue YP_253953.1 similar to unknown protein YP_253955.1 similar to unknown protein YP_253957.1 no similarity YP_253958.1 similar to unknown protein YP_253959.1 no similarity YP_253960.1 similar to unknown protein YP_253961.1 similar to unknown protein YP_253963.1 no similarity YP_253964.1 hypothetical protein, similar to thioredoxin YP_253965.1 hypothetical protein, similar to nucleotidyl transferase/hydrolase domain YP_253966.1 part of multienzyme complex composed of H, L, P, and T proteins which catalyzes oxidation of glycine to yield carbon dioxide, ammonia, 5,10-CH2-H4folate and a reduced pyridine nucleotide; protein H is involved in transfer of methylamine group from the P to T protein; covalently bound to a lipoyl cofactor YP_253967.1 hypothetical protein, similar to arsenate reductase YP_253968.1 hypothetical protein, similar to thioredoxin YP_253969.1 similar to unknown protein YP_253970.1 catalyzes the dehydration of 3-dehydroquinate to form 3-dehydroshikimate in aromatic amino acid biosynthesis YP_253971.1 hypothetical protein, similar to general stress protein 170 YP_253972.1 similar to unknown protein YP_253973.1 hypothetical protein, similar to transporter, LysE family YP_253974.1 hypothetical protein, similar to phosphoglycerate mutase YP_253975.1 similar to unknown protein YP_253976.1 similar to unknown protein YP_253977.1 similar to unknown protein YP_253978.1 similar to unknown protein YP_253979.1 similar to unknown protein YP_253980.1 no similarity YP_253981.1 no similarity YP_253982.1 similar to unknown protein YP_253983.1 hypothetical protein, similar to phage-related protein YP_253984.1 similar to unknown protein YP_253985.1 similar to unknown protein YP_253986.1 no similarity YP_253987.1 no similarity YP_253989.1 no similarity YP_253990.1 no similarity YP_253991.1 no similarity YP_253992.1 similar to unknown protein YP_253993.1 no similarity YP_253994.1 no similarity YP_253995.1 no similarity YP_253996.1 no similarity YP_253997.1 no similarity YP_253998.1 no similarity YP_253999.1 hypothetical protein, similar to bacteriophage terminase small subunit YP_254000.1 no similarity YP_254001.1 no similarity YP_254002.1 no similarity YP_254003.1 no similarity YP_254004.1 no similarity YP_254005.1 no similarity YP_254006.1 no similarity YP_254007.1 no similarity YP_254009.1 no similarity YP_254010.1 no similarity YP_254011.1 no similarity YP_254012.1 no similarity YP_254013.1 no similarity YP_254014.1 no similarity YP_254015.1 no similarity YP_254016.1 hypothetical protein, similar to phage repressor protein YP_254018.1 similar to unknown protein YP_254019.1 binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation YP_254021.1 carboxyesterase precursor homologue YP_254022.1 hypothetical protein, similar to preprotein translocase subunit SecG YP_254023.1 similar to unknown protein YP_254024.1 enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis YP_254025.1 catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate YP_254026.1 Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate YP_254027.1 Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway YP_254030.1 similar to unknown protein YP_254031.1 similar to unknown protein YP_254032.1 no similarity YP_254033.1 no similarity YP_254034.1 hypothetical protein, similar to cell-division inhibitor YP_254035.1 similar to unknown protein YP_254036.1 hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates YP_254037.1 similar to unknown protein YP_254038.1 similar to unknown protein YP_254039.1 similar to unknown protein YP_254041.1 similar to unknown protein YP_254042.1 hypothetical protein, similar to O-acetyltransferase YP_254043.1 transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein YP_254044.1 catalyzes the phosphorylation of the phosphocarrier protein HPr of the bacterial phosphotransferase system YP_254045.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate YP_254046.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion YP_254047.1 similar to unknown protein YP_254048.1 similar to unknown protein YP_254051.1 hypothetical protein, similar to autolysin YP_254053.1 functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond SecA1; SecA2 is not essential and seems to play a role in secretion of a subset of proteins YP_254054.1 similar to unknown protein YP_254055.1 hypothetical protein, similar to comF operon protein 3 YP_254056.1 hypothetical protein, similar to comF operon protein 1 YP_254057.1 similar to unknown protein YP_254058.1 similar to unknown protein YP_254060.1 similar to unknown protein YP_254061.1 similar to unknown protein YP_254062.1 similar to unknown protein YP_254063.1 catalyzes the release of the N-terminal amino acid from a tripeptide YP_254064.1 hypothetical protein, similar to glycerate kinase YP_254065.1 similar to unknown protein YP_254066.1 no similarity YP_254067.1 similar to unknown protein YP_254068.1 catalyzes the reduction of UDP-N-acetylglucosamine enolpyruvate to form UDP-N-acetylmuramate in peptidoglycan biosynthesis YP_254069.1 similar to unknown protein YP_254070.1 hypothetical protein, similar to ferrichrome ABC transporter [truncated] YP_254071.1 hypothetical protein, similar to ferrichrome ABC transporter [truncated] YP_254072.1 hypothetical protein, similar to ferrichrome ABC transporter YP_254073.1 hypothetical protein, similar to ferrichrome ABC transporter ATP-binding protein YP_254074.1 hypothetical protein, similar to ferrichrome ABC transporter permease YP_254075.1 hypothetical protein, similar to ferrichrome ABC transporter permease YP_254076.1 B2 or R2 protein; type 1b enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdE YP_254077.1 Catalyzes the rate-limiting step in dNTP synthesis YP_254078.1 in Salmonella NrdI has a stimulatory effect on the ribonucleotide reductase activity of NrdH with NrdEF YP_254079.1 similar to unknown protein YP_254080.1 NADPH-dependent; catalyzes the reduction of 7-cyano-7-deazaguanine to 7-aminomethyl-7-deazaguanine in queuosine biosynthesis YP_254081.1 hypothetical protein, similar to di-tripepride ABC transporter YP_254082.1 hypothetical protein, similar to multidrug resistance protein YP_254083.1 similar to unknown protein YP_254084.1 catalyzes the formation of L-histidinol phosphate from imidazole-acetol phosphate and glutamate in histidine biosynthesis YP_254085.1 hypothetical protein, similar to di-tripeptide ABC transporter (membrane protein) YP_254086.1 hypothetical protein, similar to periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein) YP_254087.1 hypothetical protein, similar to glycine betaine/carnitine/choline ABC transporter (ATP-binding protein) YP_254089.1 hypothetical protein, similar to ABC transporter ATP-binding protein YP_254090.1 hypothetical protein, similar to divalent heavy-metal cations transporter YP_254091.1 no similarity YP_254092.1 truncated YP_254093.1 truncated YP_254094.1 hypothetical protein, similar to anion-binding protein YP_254095.1 similar to unknown protein YP_254096.1 hypothetical protein, similar to urea amidolyase YP_254097.1 similar to unknown protein YP_254098.1 hypothetical protein, similar to para-aminobenzoate synthase component I YP_254099.1 hypothetical protein, similar to para-aminobenzoate synthase component I YP_254100.1 hypothetical protein, similar to anthranilate synthase component II YP_254101.1 hypothetical protein, similar to aluminum resistance protein YP_254103.1 hypothetical protein, similar to coenzyme PQQ synthesis protein YP_254104.1 similar to unknown protein YP_254105.1 hypothetical protein, similar to CsbB stress response protein YP_254107.1 hypothetical protein, similar to plant-metabolite dehydrogenases YP_254108.1 hypothetical protein, similar to hemolysin YP_254111.1 hypothetical protein, similar to transcription repressor of fructose operon YP_254112.1 hypothetical protein, similar to transcription regulation protein YP_254113.1 similar to unknown protein YP_254115.1 similar to unknown protein YP_254116.1 similar to unknown protein YP_254117.1 similar to unknown protein YP_254118.1 hypothetical protein, similar to deoxyribodipyrimidine photolyase YP_254119.1 similar to unknown protein YP_254120.1 similar to unknown protein YP_254121.1 hypothetical protein, similar to cobalamin synthesis related protein YP_254122.1 hypothetical protein, similar to transcriptional regulator YP_254123.1 hypothetical protein, similar to ABC transporter required for expression of cytochrome bd YP_254124.1 hypothetical protein, similar to ABC transporter required for expression of cytochrome bd YP_254125.1 bacA; BacA; phosphatase activity in Escherichia coli not kinase; involved in bacitracin resistance as bacitracin supposedly sequesters undecaprenyl disphosphate which reduces the pool of lipid carrier available to the cell YP_254126.1 similar to unknown protein YP_254127.1 similar to unknown protein YP_254128.1 similar to unknown protein YP_254129.1 similar to unknown protein YP_254130.1 similar to unknown protein YP_254131.1 similar to unknown protein YP_254132.1 similar to unknown protein YP_254133.1 similar to unknown protein YP_254134.1 similar to unknown protein YP_254135.1 hypothetical protein, similar to sugar efflux transpoter YP_254136.1 hypothetical protein, similar to transcriptional regulator, LysR family YP_254137.1 similar to unknown protein YP_254138.1 similar to unknown protein YP_254139.1 similar to unknown protein YP_254140.1 similar to unknown protein YP_254141.1 similar to unknown protein YP_254143.1 similar to unknown protein YP_254144.1 secretory antigen SsaA homologue YP_254145.1 hypothetical protein, similar to low-affinity inorganic phosphate transporter YP_254146.1 similar to unknown protein YP_254149.1 hypothetical protein, similar to signal transduction histidine kinase YP_254150.1 hypothetical protein, similar to response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain YP_254151.1 similar to unknown protein YP_254152.1 hypothetical protein, similar to ribosomal protein-alanine acetyltransferase YP_254153.1 hypothetical protein, similar to lipase LipA YP_254154.1 no similarity YP_254155.1 similar to unknown protein YP_254156.1 similar to unknown protein YP_254157.1 hypothetical protein, similar to dihydroxyacetone kinase DhaK3 YP_254158.1 hypothetical protein, similar to dihydroxyacetone kinase YP_254159.1 with DhaL and DhaM forms dihydroxyacetone kinase, which is responsible for phosphorylating dihydroxyacetone; DhaK is the dihydroxyacetone binding subunit of the dihydroxyacetone kinase YP_254163.1 similar to unknown protein YP_254164.1 hypothetical protein, similar to pyrimidine nucleoside transporter YP_254168.1 ABC transporter AurT homolog YP_254174.1 with TagG is involved in the export of teichoic acids YP_254176.1 similar to unknown protein YP_254177.1 iron dependent transcriptional regulator/repressor homolog YP_254178.1 hypothetical protein, similar to NhaP-type Na+/H+ and K+/H+ antiporters YP_254179.1 no similarity YP_254180.1 dapE-encoded N-succinyl-L,L-diaminopimelic acid desuccinylase (DapE), catalyzes the hydrolysis of N-succinyl-L,Ldiaminopimelate L,L-SDAP to L,L-diaminopimelate and succinate. It is a metalloprotease containing dinuclear active sites. Its structure is similar to the carboxypeptidase G2 from Pseudomonas sp. strain RS-16 and the aminopeptidase from Aeromonas proteolytica. YP_254181.1 similar to unknown protein YP_254183.1 no similarity YP_254184.1 subunit G of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali YP_254185.1 subunit F of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali YP_254186.1 subunit E of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; in S. meliloti it is known to be involved specifically with K+ transport YP_254187.1 subunit D of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; contains an oxidoreductase domain; catalyzes the transfer of electrons from NADH to ubiquinone; in S. meliloti it is known to be involved specifically with K+ transport YP_254188.1 subunit C of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali YP_254189.1 subunit B of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali YP_254190.1 subunit A of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali YP_254192.1 similar to unknown protein YP_254193.1 similar to unknown protein YP_254194.1 similar to unknown protein YP_254195.1 similar to unknown protein YP_254198.1 hypothetical protein, similar to esterase/lipase YP_254199.1 similar to unknown protein YP_254200.1 similar to unknown protein YP_254201.1 hypothetical protein, similar to 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoic acid hydrolase YP_254202.1 hypothetical protein, similar to L-2-haloalkanoic acid dehalogenase YP_254204.1 hypothetical protein, similar to iron-binding protein YP_254205.1 similar to unknown protein YP_254207.1 hypothetical protein, similar to endonuclease III YP_254208.1 catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase YP_254209.1 similar to unknown protein YP_254210.1 similar to unknown protein YP_254211.1 truncated YP_254212.1 no similarity YP_254213.1 no similarity YP_254214.1 similar to unknown protein YP_254215.1 similar to unknown protein YP_254216.1 no similarity YP_254217.1 similar to unknown protein YP_254218.1 similar to unknown protein YP_254222.1 similar to unknown protein YP_254223.1 hypothetical protein, similar to transcriptional regulator YP_254226.1 no similarity YP_254227.1 similar to unknown protein YP_254228.1 similar to unknown protein YP_254229.1 hypothetical protein, similar to transcriptional regulator YP_254230.1 no similarity YP_254231.1 similar to unknown protein YP_254232.1 similar to unknown protein YP_254233.1 similar to unknown protein YP_254234.1 no similarity YP_254235.1 no similarity YP_254236.1 hypothetical protein,similar to ABC transporter permease YP_254237.1 no similarity YP_254241.1 similar to unknown protein YP_254242.1 similar to unknown protein YP_254243.1 similar to unknown protein YP_254244.1 similar to unknown protein YP_254245.1 hypothetical protein, similar to oxidoreductase ion channel YP_254246.1 similar to unknown protein YP_254247.1 mercuric reductase homologue [truncated] YP_254250.1 no similarity YP_254251.1 hypothetical protein, similar to phage phi187 cell hydrolase Ply187 YP_254252.1 no similarity YP_254253.1 no similarity YP_254254.1 no similarity YP_254255.1 no similarity YP_254256.1 no similarity YP_254257.1 hypothetical protein, similar to phage-related pre-neck appendage protein YP_254258.1 no similarity YP_254259.1 no similarity YP_254260.1 hypothetical protein, similar to tape measure protein YP_254261.1 no similarity YP_254262.1 no similarity YP_254263.1 no similarity YP_254264.1 no similarity YP_254265.1 no similarity YP_254266.1 no similarity YP_254267.1 no similarity YP_254268.1 no similarity YP_254269.1 hypothetical protein, similar to bacteriophage major head protein YP_254270.1 hypothetical protein, similar to bacteriophage minor capsid protein YP_254271.1 no similarity YP_254272.1 hypothetical protein, similar to bacteriophage portal protein YP_254274.1 no similarity YP_254275.1 no similarity YP_254276.1 no similarity YP_254277.1 no similarity YP_254278.1 no similarity YP_254279.1 no similarity YP_254280.1 no similarity YP_254281.1 no similarity YP_254282.1 no similarity YP_254284.1 no similarity YP_254285.1 no similarity YP_254286.1 no similarity YP_254287.1 no similarity YP_254288.1 no similarity YP_254289.1 no similarity YP_254290.1 no similarity YP_254291.1 no similarity YP_254292.1 no similarity YP_254293.1 no similarity YP_254294.1 no similarity YP_254295.1 no similarity YP_254296.1 no similarity YP_254297.1 no similarity YP_254298.1 no similarity YP_254299.1 no similarity YP_254300.1 no similarity YP_254301.1 no similarity YP_254302.1 no similarity YP_254303.1 no similarity YP_254304.1 no similarity YP_254305.1 no similarity YP_254306.1 no similarity YP_254307.1 no similarity YP_254308.1 no similarity YP_254309.1 hypothetical protein, similar to phage repressor protein YP_254310.1 no similarity YP_254312.1 mercuric reductase homologue [truncated] YP_254314.1 similar to unknown protein YP_254318.1 hypothetical protein, similar to lipoate-protein ligase A YP_254319.1 in Salmonella this enzyme is required for ethanolamine catabolism; has higher affinity for CoA than Pta YP_254320.1 similar to unknown protein YP_254321.1 similar to unknown protein YP_254322.1 similar to unknown protein YP_254323.1 hypothetical protein, similar to cationic amino acid transporter YP_254324.1 similar to unknown protein YP_254325.1 similar to unknown protein YP_254326.1 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine YP_254328.1 similar to unknown protein YP_254329.1 proline/betaine transporter homologue YP_254330.1 similar to unknown protein YP_254331.1 similar to unknown protein YP_254333.1 hypothetical protein, similar to acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II YP_254334.1 similar to unknown protein YP_254335.1 hexulose-6-phosphate synthase homolog YP_254336.1 similar to unknown protein YP_254337.1 similar to unknown protein YP_254338.1 similar protein in Methanocaldococcus converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate as the first step in methanopterin biosynthesis YP_254339.1 hypothetical protein, similar to UDP-N-acetylmuramyl pentapeptide synthase YP_254340.1 similar to unknown protein YP_254341.1 hypothetical protein, similar to cell-surface adhesin SdrF YP_254342.1 no similarity YP_254343.1 truncated YP_254344.1 truncated YP_254345.1 truncated YP_254346.1 hypothetical protein, similar to fibrinogen-binding protein SdrG [truncated] YP_254347.1 similar to unknown protein YP_254348.1 similar to unknown protein YP_254349.1 similar to unknown protein YP_254350.1 deoxypurine kinase homolog YP_254351.1 deoxyguanosine kinase homolog YP_254352.1 hypothetical protein, similar to phosphoglycolate phosphatase YP_254353.1 similar to unknown protein YP_254354.1 no similarity YP_254355.1 similar to unknown protein YP_254356.1 no similarity YP_254357.1 no similarity YP_254358.1 hypothetical protein, similar to acetyltransferase YP_254359.1 similar to unknown protein YP_254360.1 no similarity YP_254361.1 no similarity YP_254362.1 truncated YP_254363.1 truncated YP_254364.1 catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids YP_254365.1 hypothetical protein, similar to UDP-glucose 4-epimerase related protein YP_254366.1 no similarity YP_254367.1 hypothetical protein, similar to 5'-nucleotidase YP_254368.1 catalyzes the formation of L-proline from L-ornithine YP_254369.1 no similarity YP_254370.1 hypothetical protein, similar to MutT-like protein YP_254371.1 hypothetical protein, similar to acetyltransferase YP_254372.1 catalyzes the formation of 2-amino-3-oxobutanoate from acetyl-CoA and glycine YP_254373.1 hypothetical protein, similar to N-acyl-L-amino acid amidohydrolase YP_254374.1 EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu YP_254375.1 EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene YP_254376.1 binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit YP_254377.1 interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance YP_254378.1 in Bacillus subtilis this non-essential protein associates with the ribosome YP_254379.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Subunit beta' binds to sigma factor allowing it to bind to the -10 region of the promoter YP_254380.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme YP_254381.1 similar to unknown protein YP_254382.1 present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulates GTPase activity of translation factors YP_254383.1 binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit YP_254384.1 truncated YP_254385.1 truncated YP_254386.1 in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA YP_254387.1 binds directly to 23S ribosomal RNA YP_254389.1 forms a complex with SecY and SecG; SecYEG forms a protein-conducting channel to which secA binds and translocates targeted polypeptides across the cytoplasmic membrane, a process driven by ATP and a proton-motive force YP_254390.1 hypothetical protein, similar to DNA-dependent RNA polymerase sigma subunit YP_254391.1 similar to unknown protein YP_254392.1 hypothetical protein, similar to tRNA/rRNA methyltransferase YP_254393.1 similar to unknown protein YP_254394.1 catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA YP_254396.1 Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation YP_254397.1 similar to unknown protein YP_254398.1 Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents YP_254400.1 hypothetical protein, similar to creatine kinase YP_254401.1 similar to unknown protein YP_254402.1 transcription repressor of class III stress genes homologue YP_254404.1 with PdxST is involved in the biosynthesis of pyridoxal 5'-phosphate; PdxT catalyzes the hydrolysis of glutamine to glutamate and ammonia; PdxS utilizes the ammonia to synthesize pyridoxal 5'-phosphate YP_254405.1 with PdxT forms pyridoxal 5'-phosphate from glutamine, either ribose 5-phosphate or ribulose 5-phosphate, and either glyceraldehyde 3-phosphate or dihydroxyacetone phosphate YP_254406.1 hypothetical protein, similar to transcriptional regulator YP_254407.1 similar to unknown protein YP_254408.1 class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1 YP_254413.1 becomes active under oxidative stress; four conserved cysteines bind a zinc atom when they are in the reduced state and the enzyme is inactive; oxidative stress results in oxidized cysteines, release of zinc, and binding of Hsp33 to aggregation-prone proteins; forms dimers and higher order oligomers YP_254414.1 no similarity YP_254417.1 similar to unknown protein YP_254418.1 polyribonucleotide nucleotidyltransferase homolog YP_254419.1 hypothetical protein, similar to cell-division initiation protein divIC YP_254420.1 similar to unknown protein YP_254421.1 similar to unknown protein YP_254422.1 hypothetical protein, similar to low temperature requirement B protein YP_254424.1 Enables the recycling of peptidyl-tRNAs produced at termination of translation YP_254425.1 the Ctc family of proteins consists of two types, one that contains the N-terminal ribosomal protein L25 domain only which in Escherichia coli binds the 5S rRNA while a subset of proteins contain a C-terminal extension that is involved in the stress response YP_254426.1 catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP YP_254427.1 gcaD; forms a homotrimer; catalyzes the acetylation of glucosamine-1-phosphate and uridylation of N-acetylglucosamine-1-phosphate to produce UDP-GlcNAc; function in cell wall synthesis YP_254428.1 stage V sporulation protein G; essential for spore formation and a negative regulator of asymmetric septation in Bacillus; involved in methicillin-resistance, biofilm formation and capsular polysaccharide synthesis in Staphylococcus YP_254430.1 pur operon repressor homologue YP_254431.1 An essential enzyme in the nonmevalonate pathway of isopentenyl diphosphate and dimethylallyl diphosphate biosynthesis YP_254432.1 VEG protein homologue YP_254433.1 catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin YP_254434.1 hypothetical protein,similar to primase-related protein YP_254436.1 methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content YP_254437.1 hypothetical protein,similar to tetrapyrrole (Corrin/Porphyrin) methylases YP_254438.1 similar to unknown protein YP_254439.1 hypothetical protein,similar to ubiE/COQ5 methyltransferase family YP_254440.1 in Bacillus subtilis this protein is involved in the negative regulation of DNA replication initiation; interacts with DnaN and DnaA YP_254441.1 hypothetical protein, similar to signal peptidase II homologue YP_254442.1 DNA polymerase III delta prime subunit homolog YP_254443.1 similar to unknown protein YP_254444.1 catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to thymidine monophosphate (dTMP) to form thymidine diphosphate (dTDP) YP_254445.1 hypothetical protein, similar to lysine decarboxylase YP_254446.1 spermidine acetyltransferase homolog YP_254447.1 involved in a recombinational process of DNA repair, independent of the recBC complex YP_254448.1 similar to unknown protein YP_254450.1 hypothetical protein, similar to acetyltransferase YP_254451.1 hypothetical protein, similar to trehalose operon transcriptional repressor YP_254454.1 glutamate synthase is composed of subunits alpha and beta; beta subunit is a flavin adenine dinucleotide-NADPH dependent oxidoreductase; provides electrons to the alpha subunit, which binds L-glutamine and 2-oxoglutarate and forms L-glutamate YP_254457.1 similar to unknown protein YP_254458.1 similar to unknown protein YP_254459.1 hypothetical protein, similar to acetyltransferase GNAT family YP_254460.1 similar to unknown protein YP_254461.1 similar to unknown protein YP_254462.1 hypothetical protein, similar to autolysin (N-acetylmuramoyl-L-alanine amidase) YP_254464.1 cysteine synthase homologue YP_254465.1 similar to unknown protein YP_254466.1 no similarity YP_254467.1 hypothetical protein, similar to sodium-dependent transporter YP_254468.1 no similarity YP_254469.1 similar to unknown protein YP_254470.1 hypothetical protein, similar to carboxylesterase YP_254471.1 similar to unknown protein YP_254472.1 similar to unknown protein YP_254473.1 hypothetical protein, similar to acetyltransferase, GNAT family YP_254474.1 similar to unknown protein YP_254475.1 similar to unknown protein YP_254476.1 Catalyzes the transfer of electrons from NADH to ubiquinone YP_254477.1 no similarity YP_254478.1 similar to unknown protein YP_254479.1 hypothetical protein, similar to acetyltransferase, GNAT family YP_254480.1 no similarity YP_254481.1 no similarity YP_254482.1 hypothetical protein, similar to Na+-transporting ATP synthase YP_254483.1 no similarity YP_254484.1 hypothetical protein, similar to bacteriophage terminase small subunit YP_254485.1 similar to unknown protein YP_254486.1 similar to unknown protein YP_254489.1 hypothetical protein, similar to SAP domain protein from Streptococcus pneumoniae TIGR4 YP_254491.1 no similarity YP_254493.1 no similarity YP_254494.1 similar to unknown protein YP_254495.1 similar to unknown protein YP_254497.1 contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway YP_254500.1 Catalyzes the transfer of the phosphoribosyl moiety from 5-phospho--D-ribosyl-1-pyrophosphate (PRib-PP) to the 6-oxo-guanine and -xanthine YP_254501.1 similar to unknown protein YP_254502.1 similar to unknown protein YP_254503.1 similar to unknown protein YP_254504.1 hypothetical protein, similar to proton/sodium-glutamate symport protein YP_254505.1 hypothetical protein, similar to nitro/flavin reductase YP_254506.1 hypothetical protein,similar to 2-hydroxypenta-2,4-dienoate hydratase YP_254509.1 similar to unknown protein YP_254510.1 hypothetical protein, similar to phosphoglycerate mutase Gpm3p [truncated] YP_254511.1 hypothetical protein,similar to dihydrodipicolinate reductase YP_254512.1 truncated YP_254513.1 truncated YP_254514.1 no similarity YP_254515.1 hypothetical protein, similar to acetyltransferase, GNAT family YP_254516.1 similar to unknown protein YP_254517.1 no similarity YP_254518.1 no similarity YP_254519.1 similar to unknown protein YP_254520.1 similar to unknown protein YP_254521.1 no similarity YP_254525.1 hypothetical protein,similar to transcriptional regulator [truncated] YP_254526.1 similar to unknown protein YP_254527.1 hypothetical protein,similar to transcriptional regulator YP_254528.1 hypothetical protein, similar to ABC transporter, ATP-binding protein YP_254529.1 hypothetical protein,similar to ABC transporter efflux protein, DrrB family YP_254530.1 no similarity YP_254531.1 similar to unknown protein YP_254532.1 hypothetical protein,similar to immunodominant antigen B YP_254533.1 truncated YP_254534.1 truncated YP_254535.1 truncated YP_254536.1 truncated YP_254537.1 similar to unknown protein YP_254538.1 truncated YP_254539.1 similar to unknown protein YP_254540.1 no similarity YP_254541.1 binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit YP_254543.1 binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21 YP_254544.1 hypothetical protein, similar to 1,4-beta-N-acetylmuramidase YP_254545.1 similar to unknown protein YP_254546.1 translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1 YP_254547.1 similar to unknown protein YP_254548.1 similar to unknown protein YP_254549.1 hypothetical protein, similar to transcription terminator YP_254550.1 hypothetical protein, similar to cystathionine gamma-synthase YP_254551.1 hypothetical protein, similar to cystathionine beta-lyase YP_254552.1 catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine; expressed in B. subtilis under methionine starvation conditions YP_254553.1 catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine to form methionine YP_254554.1 similar to unknown protein YP_254555.1 hypothetical protein,similar to myo-inositol-1(or 4)-monophosphatase YP_254556.1 no similarity YP_254557.1 hypothetical protein,similar to ABC transporter (ATP-binding protein) YP_254558.1 similar to unknown protein YP_254559.1 hypothetical protein,similar to methylglyoxalase YP_254561.1 Converts D-mannonate to D-mannuronate YP_254562.1 catalyzes the formation of 2-dehydro-3-deoxy-D-gluconate from mannonate YP_254563.1 catalyzes the interconversion of D-glucuronate to D-fructuronate or D-galacturonate to D-tagaturonate; functions in glucuronic and galacturonic metabolism YP_254564.1 hypothetical protein,similar to Na+:galactoside symporter YP_254565.1 hypothetical protein,similar to 2-keto-3-deoxygluconate kinase YP_254566.1 hypothetical protein,similar to 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase YP_254567.1 hypothetical protein,similar to transcriptional regulator YP_254568.1 no similarity YP_254569.1 hypothetical protein,similar to beta-hexosamidase A YP_254570.1 glycine betaine/proline ABC transporter (ATP-binding protein) homolog YP_254571.1 truncated YP_254572.1 truncated YP_254573.1 hypothetical protein, similar to ribosomal-protein-serine N-acetyltransferase YP_254575.1 hypothetical protein,similar to TcaA protein YP_254576.1 no similarity YP_254578.1 similar to unknown protein YP_254581.1 similar to unknown protein YP_254582.1 no similarity YP_254583.1 hypothetical protein, similar to transcriptional regulator YP_254584.1 no similarity YP_254585.1 hypothetical protein,similar to transcriptional regulator YP_254586.1 similar to unknown protein YP_254587.1 similar to unknown protein YP_254588.1 hypothetical protein, similar to DNA-binding protein Spo0J-like homolog YP_254589.1 glucose-inhibited division protein B; SAM-dependent methyltransferase; methylates the N7 position of guanosine in position 527 of 16S rRNA YP_254590.1 GidA; glucose-inhibited cell division protein A; involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U) of the wobble uridine base in some tRNAs YP_254591.1 in Escherichia coli this protein is involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2-thiouridine, which is found in the wobble position of some tRNAs and affects ribosomal frameshifting; shows potassium-dependent dimerization and GTP hydrolysis; also involved in regulation of glutamate-dependent acid resistance and activation of gadE YP_254592.1 protein component of RNaseP which catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'terminus; this enzyme also cleaves other RNA substrates YP_254593.1 in Escherichia coli transcription of this gene is enhanced by polyamines YP_254594.1 catalyzes resistance to fosfomycin by the addition of a thiol cofactor YP_254596.1 no similarity YP_254597.1 rRNA adenine N-6-methyltransferase (Macrolide-lincosamide-streptogramin B resistance protein) (Erythromycin resistance protein) YP_254600.1 no similarity YP_254601.1 no similarity YP_254602.1 hypothetical protein, similar to multidrug-efflux transporter YP_254603.1 hypothetical protein, similar to transcriptional regulator, MarR family YP_254604.1 similar to unknown protein YP_254605.1 hypothetical protein, similar to cytochrome P450-like enzyme