-- dump date   	20140620_080942
-- class       	Genbank::misc_feature
-- table       	misc_feature_note
-- id	note
519441000001	chromosomal replication initiation protein; Reviewed; Region: dnaA; PRK00149
519441000002	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
519441000003	Walker A motif; other site
519441000004	ATP binding site [chemical binding]; other site
519441000005	Walker B motif; other site
519441000006	C-terminal domain of bacterial DnaA proteins. The DNA-binding C-terminal domain of DnaA contains a helix-turn-helix motif that specifically interacts with the DnaA box, a 9-mer motif that occurs repetitively in the replication origin oriC. Multiple...; Region: Bac_DnaA_C; cd06571
519441000007	DnaA box-binding interface [nucleotide binding]; other site
519441000008	Branched-chain amino acid transport protein; Region: Branch_AA_trans; cl00547
519441000009	Sialidases or neuraminidases function to bind and hydrolyze terminal sialic acid residues from various glycoconjugates as well as playing roles in pathogenesis, bacterial nutrition and cellular interactions. They have a six-bladed, beta-propeller fold...; Region: Sialidase; cd00260
519441000010	catalytic site [active]
519441000011	Asp-box motif; other site
519441000012	haemagglutination activity domain; Region: Haemagg_act; pfam05860
519441000013	DNA mismatch repair protein MutS; Provisional; Region: PRK05399
519441000014	MutS domain I; Region: MutS_I; pfam01624
519441000015	MutS domain II; Region: MutS_II; pfam05188
519441000016	MutS domain III; Region: MutS_III; pfam05192
519441000017	ATP-binding cassette domain of MutS1 homolog; Region: ABC_MutS1; cd03284
519441000018	Walker A/P-loop; other site
519441000019	ATP binding site [chemical binding]; other site
519441000020	Q-loop/lid; other site
519441000021	ABC transporter signature motif; other site
519441000022	Walker B; other site
519441000023	D-loop; other site
519441000024	H-loop/switch region; other site
519441000025	isopentenyl pyrophosphate isomerase; Provisional; Region: PRK05437
519441000026	TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl17186
519441000027	phosphate binding site [ion binding]; other site
519441000028	Protein of unknown function (DUF2185); Region: DUF2185; cl02019
519441000029	30S ribosomal protein S9; Reviewed; Region: rpsI; PRK00132
519441000030	Ribosomal protein L13.  Protein L13, a large ribosomal subunit protein, is one of five proteins required for an early folding intermediate of 23S rRNA in the assembly of the large subunit. L13 is situated on the bottom of the large subunit, near the...; Region: Ribosomal_L13; cd00392
519441000031	23S rRNA interface [nucleotide binding]; other site
519441000032	L3 interface [polypeptide binding]; other site
519441000033	ABC-type cobalt transport system, ATPase component [Inorganic ion transport and metabolism]; Region: CbiO; COG1122
519441000034	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
519441000035	Walker A/P-loop; other site
519441000036	ATP binding site [chemical binding]; other site
519441000037	Q-loop/lid; other site
519441000038	ABC transporter signature motif; other site
519441000039	Walker B; other site
519441000040	D-loop; other site
519441000041	H-loop/switch region; other site
519441000042	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Region: Gp_dh_N; pfam00044
519441000043	glyceraldehyde-3-phosphate dehydrogenase, type I; Region: GAPDH-I; TIGR01534
519441000044	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; pfam02800
519441000045	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1481
519441000046	Sporulation Regulator WhiA N terminal; Region: WhiA_N; pfam10298
519441000047	seryl-tRNA synthetase; Provisional; Region: PRK05431
519441000048	Seryl-tRNA synthetase N-terminal domain; Region: Seryl_tRNA_N; pfam02403
519441000049	Seryl-tRNA synthetase (SerRS) class II core catalytic domain. SerRS is responsible for the attachment of serine to the 3' OH group of ribose of the appropriate tRNA. This domain It is primarily responsible for ATP-dependent formation of the enzyme...; Region: SerRS_core; cd00770
519441000050	dimer interface [polypeptide binding]; other site
519441000051	active site
519441000052	motif 1; other site
519441000053	motif 2; other site
519441000054	motif 3; other site
519441000055	Endo-N-acetylmuramidases (muramidases) are lysozymes (also referred to as peptidoglycan hydrolases) that degrade bacterial cell walls by catalyzing the hydrolysis of 1,4-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues; Region: GH25_muramidase; cl10448
519441000056	Glycosyl hydrolases family 25; Region: Glyco_hydro_25; pfam01183
519441000057	active site
519441000058	ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only]; Region: Uup; COG0488
519441000059	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
519441000060	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
519441000061	ABC transporter; Region: ABC_tran_2; pfam12848
519441000062	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
519441000063	UDP-N-acetylmuramyl pentapeptide synthase [Cell envelope biogenesis, outer membrane]; Region: MurF; COG0770
519441000064	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
519441000065	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
519441000066	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
519441000067	phospho-N-acetylmuramoyl-pentapeptide-transferase; Provisional; Region: mraY; PRK00108
519441000068	Phospho-N-acetylmuramoyl-pentapeptide-transferase (mraY) is an enzyme responsible for the formation of the first lipid intermediate in the synthesis of bacterial cell wall peptidoglycan. It catalyzes the formation of...; Region: GT_MraY; cd06852
519441000069	Mg++ binding site [ion binding]; other site
519441000070	putative catalytic motif [active]
519441000071	putative substrate binding site [chemical binding]; other site
519441000072	UDP-N-acetylmuramoylalanine-D-glutamate ligase [Cell envelope biogenesis, outer membrane]; Region: MurD; COG0771
519441000073	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
519441000074	Cell cycle protein; Region: FTSW_RODA_SPOVE; cl00511
519441000075	undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase; Provisional; Region: murG; PRK00726
519441000076	MurG is an N-acetylglucosaminyltransferase, the last enzyme involved in the intracellular phase of peptidoglycan biosynthesis. It transfers N-acetyl-D-glucosamine (GlcNAc) from UDP-GlcNAc to the C4 hydroxyl of a lipid-linked N-acetylmuramoyl pentapeptide...; Region: GT1_MurG; cd03785
519441000077	active site
519441000078	homodimer interface [polypeptide binding]; other site
519441000079	Pyroglutamyl peptidase (PGP) type I, also known as pyrrolidone carboxyl peptidase (pcp) type I:  Enzymes responsible for cleaving pyroglutamate (pGlu) from the N-terminal end of specialized proteins. The N-terminal pGlu protects these proteins from...; Region: Peptidase_C15; cd00501
519441000080	putative substrate binding pocket [chemical binding]; other site
519441000081	AC domain interface; other site
519441000082	catalytic triad [active]
519441000083	AB domain interface; other site
519441000084	interchain disulfide; other site
519441000085	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
519441000086	Major Facilitator Superfamily; Region: MFS_1; pfam07690
519441000087	Tagatose-1,6-bisphosphate (TBP) aldolase and related Type B Class II aldolases. TBP aldolase is a tetrameric class II aldolase that catalyzes the reversible condensation of dihydroxyacetone phosphate with glyceraldehyde 3-phsophate to produce tagatose 1; Region: TBP_aldolase_IIB; cd00947
519441000088	fructose-bisphosphate aldolase; Provisional; Region: PRK09197
519441000089	intersubunit interface [polypeptide binding]; other site
519441000090	active site
519441000091	zinc binding site [ion binding]; other site
519441000092	Na+ binding site [ion binding]; other site
519441000093	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
519441000094	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
519441000095	nucleotide binding site [chemical binding]; other site
519441000096	CTP synthetase; Validated; Region: pyrG; PRK05380
519441000097	CTP synthetase (CTPs) is a two-domain protein, which consists of an N-terminal synthetase domain and C-terminal glutaminase domain. The enzymes hydrolyze the amide bond of glutamine to ammonia and glutamate at the glutaminase domains and transfer nascent...; Region: CTGs; cd03113
519441000098	Catalytic site [active]
519441000099	active site
519441000100	UTP binding site [chemical binding]; other site
519441000101	Type 1 glutamine amidotransferase (GATase1) domain found in Cytidine Triphosphate Synthetase; Region: GATase1_CTP_Synthase; cd01746
519441000102	active site
519441000103	putative oxyanion hole; other site
519441000104	catalytic triad [active]
519441000105	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
519441000106	RNA binding surface [nucleotide binding]; other site
519441000107	Recombinational DNA repair ATPase (RecF pathway) [DNA replication, recombination, and repair]; Region: RecF; COG1195
519441000108	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
519441000109	Walker A/P-loop; other site
519441000110	ATP binding site [chemical binding]; other site
519441000111	Q-loop/lid; other site
519441000112	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
519441000113	ABC transporter signature motif; other site
519441000114	Walker B; other site
519441000115	D-loop; other site
519441000116	H-loop/switch region; other site
519441000117	CarD-like/TRCF domain; Region: CarD_CdnL_TRCF; pfam02559
519441000118	DEAD-like helicases superfamily; Region: DEXDc; smart00487
519441000119	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
519441000120	ATP binding site [chemical binding]; other site
519441000121	putative Mg++ binding site [ion binding]; other site
519441000122	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
519441000123	nucleotide binding region [chemical binding]; other site
519441000124	ATP-binding site [chemical binding]; other site
519441000125	TRCF domain; Region: TRCF; pfam03461
519441000126	phosphoribosylformylglycinamidine synthase, clade II; Region: FGAM-synthase; TIGR01857
519441000127	AIR (aminoimidazole ribonucleotide) synthase related protein. This family includes Hydrogen expression/formation protein HypE, AIR synthases, FGAM (formylglycinamidine ribonucleotide) synthase and Selenophosphate synthetase (SelD). The N-terminal domain...; Region: PurM-like; cl10019
519441000128	PurL subunit of the formylglycinamide ribonucleotide amidotransferase (FGAR-AT), first repeat. FGAR-AT catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to formylglycinamidine ribonucleotide (FGAM), ADP; Region: PurL_repeat1; cd02203
519441000129	dimerization interface [polypeptide binding]; other site
519441000130	ATP binding site [chemical binding]; other site
519441000131	PurL subunit of the formylglycinamide ribonucleotide amidotransferase (FGAR-AT), second repeat. FGAR-AT catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to formylglycinamidine ribonucleotide (FGAM), ADP; Region: PurL_repeat2; cd02204
519441000132	dimerization interface [polypeptide binding]; other site
519441000133	ATP binding site [chemical binding]; other site
519441000134	Type 1 glutamine amidotransferase (GATase1)-like domain found in Formylglycinamide ribonucleotide amidotransferase; Region: GATase1_FGAR_AT; cd01740
519441000135	putative active site [active]
519441000136	catalytic triad [active]
519441000137	AIR carboxylase; Region: AIRC; pfam00731
519441000138	phosphoribosylaminoimidazole-succinocarboxamide synthase; Reviewed; Region: PRK09362
519441000139	bacterial and archaeal 5-aminoimidazole-4-(N-succinylcarboxamide) ribonucleotide (SAICAR) synthase; Region: SAICAR_synt_PurC; cd01415
519441000140	ATP binding site [chemical binding]; other site
519441000141	active site
519441000142	substrate binding site [chemical binding]; other site
519441000143	amidophosphoribosyltransferase; Provisional; Region: PRK05793
519441000144	Glutamine amidotransferases class-II (GN-AT)_GPAT- type. This domain is found at the N-terminus of  glutamine phosphoribosylpyrophosphate (Prpp) amidotransferase (GPATase) . The glutaminase domain catalyzes amide nitrogen transfer from glutamine to the...; Region: GPATase_N; cd00715
519441000145	tetramer interface [polypeptide binding]; other site
519441000146	active site
519441000147	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
519441000148	active site
519441000149	phosphoribosylaminoimidazole synthetase; Provisional; Region: PRK05385
519441000150	PurM (Aminoimidazole Ribonucleotide [AIR] synthetase), one of eleven enzymes required for purine biosynthesis, catalyzes the conversion of formylglycinamide ribonucleotide (FGAM) and ATP to AIR, ADP, and Pi, the fifth step in de novo purine biosynthesis; Region: PurM; cd02196
519441000151	dimerization interface [polypeptide binding]; other site
519441000152	putative ATP binding site [chemical binding]; other site
519441000153	Folate-dependent phosphoribosylglycinamide formyltransferase PurN [Nucleotide transport and metabolism]; Region: PurN; COG0299
519441000154	Phosphoribosylglycinamide formyltransferase (GAR transformylase, GART); Region: FMT_core_GART; cd08645
519441000155	active site
519441000156	substrate binding site [chemical binding]; other site
519441000157	cosubstrate binding site; other site
519441000158	catalytic site [active]
519441000159	bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; Provisional; Region: purH; PRK00881
519441000160	Inosine monophosphate cyclohydrolase domain. This is the N-terminal domain in the purine biosynthesis pathway protein ATIC (purH). The bifunctional ATIC protein contains a C-terminal  ATIC formylase domain that formylates...; Region: IMPCH; cd01421
519441000161	purine monophosphate binding site [chemical binding]; other site
519441000162	dimer interface [polypeptide binding]; other site
519441000163	putative catalytic residues [active]
519441000164	AICARFT/IMPCHase bienzyme; Region: AICARFT_IMPCHas; smart00798
519441000165	AICARFT/IMPCHase bienzyme; Region: AICARFT_IMPCHas; cl03362
519441000166	phosphoribosylamine--glycine ligase; Provisional; Region: PRK00885
519441000167	Phosphoribosylglycinamide synthetase, N domain; Region: GARS_N; pfam02844
519441000168	Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Region: GARS_A; pfam01071
519441000169	Phosphoribosylglycinamide synthetase, C domain; Region: GARS_C; pfam02843
519441000170	Uncharacterized protein conserved in bacteria (DUF2087); Region: DUF2087; pfam09860
519441000171	Family 41 Carbohydrate-Binding Module from pullulanase-like enzymes; Region: CBM41_pullulanase; cd10315
519441000172	carbohydrate binding site [chemical binding]; other site
519441000173	pullulanase, type I; Region: pulA_typeI; TIGR02104
519441000174	Early set domain associated with the catalytic domain of pullulanase (also called dextrinase and alpha-dextrin endo-1,6-alpha glucosidase); Region: E_set_Pullulanase; cd02860
519441000175	Alpha amylase catalytic domain found in Pullulanase (also called dextrinase; alpha-dextrin endo-1,6-alpha glucosidase), limit dextrinase, and related proteins; Region: AmyAc_Pullulanase_LD-like; cd11341
519441000176	Ca binding site [ion binding]; other site
519441000177	active site
519441000178	catalytic site [active]
519441000179	Transposase zinc-binding domain; Region: Zn_Tnp_IS91; pfam14319
519441000180	Putative transposase; Region: Y2_Tnp; pfam04986
519441000181	Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group...; Region: Cyt_C5_DNA_methylase; cd00315
519441000182	C-5 cytosine-specific DNA methylase; Region: DNA_methylase; pfam00145
519441000183	cofactor binding site; other site
519441000184	DNA binding site [nucleotide binding]
519441000185	substrate interaction site [chemical binding]; other site
519441000186	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
519441000187	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
519441000188	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
519441000189	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
519441000190	dimer interface [polypeptide binding]; other site
519441000191	conserved gate region; other site
519441000192	putative PBP binding loops; other site
519441000193	ABC-ATPase subunit interface; other site
519441000194	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppC; COG1173
519441000195	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
519441000196	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
519441000197	dimer interface [polypeptide binding]; other site
519441000198	conserved gate region; other site
519441000199	putative PBP binding loops; other site
519441000200	ABC-ATPase subunit interface; other site
519441000201	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppD; COG0444
519441000202	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
519441000203	Walker A/P-loop; other site
519441000204	ATP binding site [chemical binding]; other site
519441000205	Q-loop/lid; other site
519441000206	ABC transporter signature motif; other site
519441000207	Walker B; other site
519441000208	D-loop; other site
519441000209	H-loop/switch region; other site
519441000210	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
519441000211	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppF; COG1124
519441000212	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
519441000213	Walker A/P-loop; other site
519441000214	ATP binding site [chemical binding]; other site
519441000215	Q-loop/lid; other site
519441000216	ABC transporter signature motif; other site
519441000217	Walker B; other site
519441000218	D-loop; other site
519441000219	H-loop/switch region; other site
519441000220	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
519441000221	ABC-type oligopeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: OppA; COG4166
519441000222	The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold; Region: PBP2_OppA; cd08504
519441000223	peptide binding site [polypeptide binding]; other site
519441000224	putative ABC transporter ATP-binding protein YbbL; Provisional; Region: PRK10247
519441000225	ATP-binding cassette domain of multidrug resistance protein-like transporters; Region: ABCC_MRP_Like; cd03228
519441000226	Walker A/P-loop; other site
519441000227	ATP binding site [chemical binding]; other site
519441000228	Q-loop/lid; other site
519441000229	ABC transporter signature motif; other site
519441000230	Walker B; other site
519441000231	D-loop; other site
519441000232	H-loop/switch region; other site
519441000233	Predicted ATPase or kinase [General function prediction only]; Region: COG0802
519441000234	tRNA threonylcarbamoyl adenosine modification protein YeaZ; Region: T6A_YeaZ; TIGR03725
519441000235	Glycoprotease family; Region: Peptidase_M22; pfam00814
519441000236	signal recognition particle-docking protein FtsY; Provisional; Region: PRK10416
519441000237	SRP54-type protein, helical bundle domain; Region: SRP54_N; pfam02881
519441000238	The signal recognition particle (SRP) mediates the transport to or across the plasma membrane in bacteria and the endoplasmic reticulum in eukaryotes. SRP recognizes N-terminal sighnal sequences of newly synthesized polypeptides at the ribosome. The...; Region: SRP; cd03115
519441000239	P loop; other site
519441000240	GTP binding site [chemical binding]; other site
519441000241	phosphotransacetylase; Reviewed; Region: eutD; PRK09653
519441000242	acetate kinase A/propionate kinase 2; Reviewed; Region: PRK00180
519441000243	propionate/acetate kinase; Provisional; Region: PRK12379
519441000244	flavodoxin FldA; Validated; Region: PRK09267
519441000245	single-stranded-DNA-specific exonuclease RecJ; Region: recJ; TIGR00644
519441000246	DHH family; Region: DHH; pfam01368
519441000247	DHHA1 domain; Region: DHHA1; pfam02272
519441000248	Protein of unknown function (DUF3298); Region: DUF3298; pfam11738
519441000249	Spermidine/putrescine-binding periplasmic protein [Amino acid transport and metabolism]; Region: PotD; COG0687
519441000250	ABC-type Fe3+ transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: AfuA; COG1840
519441000251	UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Provisional; Region: murE; PRK00139
519441000252	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
519441000253	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
519441000254	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
519441000255	Protein of unknown function (DUF2424); Region: DUF2424; pfam10340
519441000256	alpha/beta hydrolase fold; Region: Abhydrolase_3; pfam07859
519441000257	YhcR_OBF_like: A subfamily of OB-fold domains similar to the OB folds of Bacillus subtilis YhcR. YhcR is a sugar-nonspecific nuclease, which is active in the presence of Ca2+ and Mn2+. It cleaves RNA endonucleolytically, producing 3'-monophosphate...; Region: YhcR_OBF_like; cd04486
519441000258	generic binding surface II; other site
519441000259	generic binding surface I; other site
519441000260	Exonuclease-Endonuclease-Phosphatase (EEP) domain superfamily; Region: EEP; cl00490
519441000261	putative catalytic site [active]
519441000262	putative metal binding site [ion binding]; other site
519441000263	putative phosphate binding site [ion binding]; other site
519441000264	Adenine specific DNA methylase Mod [DNA replication, recombination, and repair]; Region: COG2189
519441000265	DNA methylase; Region: N6_N4_Mtase; pfam01555
519441000266	UDP-N-acetylmuramate--L-alanine ligase; Provisional; Region: murC; PRK00421
519441000267	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
519441000268	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
519441000269	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
519441000270	UDP-N-acetylmuramate dehydrogenase [Cell envelope biogenesis, outer membrane]; Region: MurB; COG0812
519441000271	FAD binding domain; Region: FAD_binding_4; pfam01565
519441000272	UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain; Region: MurB_C; pfam02873
519441000273	tRNA-dihydrouridine synthase [Translation, ribosomal structure and biogenesis]; Region: COG0042
519441000274	Dihydrouridine synthase-like (DUS-like) FMN-binding domain. Members of this family catalyze the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also...; Region: DUS_like_FMN; cd02801
519441000275	FMN binding site [chemical binding]; other site
519441000276	active site
519441000277	catalytic residues [active]
519441000278	substrate binding site [chemical binding]; other site
519441000279	50S ribosomal protein L34; Reviewed; Region: rpmH; PRK00399
519441000280	Ribonuclease P; Region: Ribonuclease_P; pfam00825
519441000281	Haemolytic domain; Region: Haemolytic; pfam01809
519441000282	membrane protein insertase, YidC/Oxa1 family, C-terminal domain; Region: yidC_oxa1_cterm; TIGR03592
519441000283	jag_K homology RNA-binding domain. The KH domain is found in proteins homologous to the Bacillus subtilis protein Jag, which is associated with SpoIIIJ and is necessary for the third stage of sporulation.  The KH motif is a beta-alpha-alpha-beta-beta...; Region: jag_KH; cd02414
519441000284	G-X-X-G motif; other site
519441000285	R3H domain found in proteins homologous to Bacillus subtilus Jag, which is associated with SpoIIIJ. SpoIIIJ is necessary for the third stage of sporulation. The name of the R3H domain comes from the characteristic spacing of the most conserved arginine...; Region: R3H_jag; cd02644
519441000286	RxxxH motif; other site
519441000287	tRNA modification GTPase TrmE; Reviewed; Region: trmE; PRK05291
519441000288	GTP-binding protein TrmE N-terminus; Region: TrmE_N; pfam10396
519441000289	trmE is a tRNA modification GTPase; Region: trmE; cd04164
519441000290	G1 box; other site
519441000291	GTP/Mg2+ binding site [chemical binding]; other site
519441000292	Switch I region; other site
519441000293	G2 box; other site
519441000294	Switch II region; other site
519441000295	G3 box; other site
519441000296	G4 box; other site
519441000297	G5 box; other site
519441000298	Catalytic cysteine-containing C-terminus of GTPase, MnmE; Region: GTPase_Cys_C; pfam12631
519441000299	Cell division septal protein [Cell envelope biogenesis, outer membrane]; Region: FtsQ; COG1589
519441000300	POTRA domain, FtsQ-type; Region: POTRA_1; pfam08478
519441000301	FtsZ is a GTPase that is similar to the eukaryotic tubulins and is essential for cell division in prokaryotes.  FtsZ is capable of polymerizing in a GTP-driven process into structures similar to those formed by tubulin. FtsZ forms a ring-shaped septum at...; Region: FtsZ_type1; cd02201
519441000302	nucleotide binding site [chemical binding]; other site
519441000303	SulA interaction site; other site
519441000304	HpaII restriction endonuclease; Region: RE_HpaII; pfam09561
519441000305	Predicted acyltransferases [Lipid metabolism]; Region: COG1835
519441000306	SGNH_hydrolase, or GDSL_hydrolase, is a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely...; Region: SGNH_hydrolase; cl01053
519441000307	active site
519441000308	catalytic triad [active]
519441000309	oxyanion hole [active]
519441000310	Possible lysine decarboxylase; Region: Lysine_decarbox; cl00695
519441000311	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
519441000312	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
519441000313	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
519441000314	Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB) [Carbohydrate transport and metabolism]; Region: FruK; COG1105
519441000315	1-phosphofructokinase (FruK), minor 6-phosphofructokinase (pfkB) and related sugar kinases. FruK plays an important role in the predominant pathway for fructose utilisation.This group also contains tagatose-6-phophate kinase, an enzyme of the tagatose...; Region: FruK_PfkB_like; cd01164
519441000316	putative substrate binding site [chemical binding]; other site
519441000317	putative ATP binding site [chemical binding]; other site
519441000318	PTS system 2-O-a-mannosyl-D-glycerate specific transporter subunit IIABC; Provisional; Region: PRK09765
519441000319	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
519441000320	active site
519441000321	phosphorylation site [posttranslational modification]
519441000322	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
519441000323	active site
519441000324	P-loop; other site
519441000325	phosphorylation site [posttranslational modification]
519441000326	Phosphotransferase system, fructose-specific IIC component [Carbohydrate transport and metabolism]; Region: FruA; COG1299
519441000327	potassium/proton antiporter; Reviewed; Region: PRK05326
519441000328	Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: KefB; COG0475
519441000329	TrkA-C domain; Region: TrkA_C; pfam02080
519441000330	TrkA-C domain; Region: TrkA_C; pfam02080
519441000331	Transcriptional regulators [Transcription]; Region: PurR; COG1609
519441000332	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
519441000333	DNA binding site [nucleotide binding]
519441000334	domain linker motif; other site
519441000335	Ligand-binding domain of DNA transcription repressor RegR and other putative regulators such as KdgR and EndR; Region: PBP1_RegR_EndR_KdgR_like; cd06283
519441000336	putative dimerization interface [polypeptide binding]; other site
519441000337	putative ligand binding site [chemical binding]; other site
519441000338	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
519441000339	2-keto-3-deoxygluconate kinase (KdgK) phosphorylates 2-keto-3-deoxygluconate (KDG) to form 2-keto-3-deoxy-6-phosphogluconate (KDGP). KDG is the common intermediate product, that allows organisms to channel D-glucuronate and/or D-galacturinate into the...; Region: KdgK; cd01166
519441000340	substrate binding site [chemical binding]; other site
519441000341	ATP binding site [chemical binding]; other site
519441000342	2-keto-3-deoxy-6-phosphogluconate aldolase [Carbohydrate transport and metabolism]; Region: Eda; COG0800
519441000343	KDPG and KHG aldolase; Region: KDPG_aldolase; cd00452
519441000344	active site
519441000345	intersubunit interface [polypeptide binding]; other site
519441000346	catalytic residue [active]
519441000347	Glycosaminoglycan (GAG) polysaccharide lyase family. This family consists of a group of secreted bacterial lyase enzymes capable of acting on glycosaminoglycans, such as hyaluronan and chondroitin, in the extracellular matrix of host tissues; Region: GAG_Lyase; cl17706
519441000348	substrate binding site [chemical binding]; other site
519441000349	catalytic residues [active]
519441000350	2-deoxy-D-gluconate 3-dehydrogenase; Provisional; Region: PRK06935
519441000351	gluconate 5-dehydrogenase (Ga5DH)-like, classical (c) SDRs; Region: Ga5DH-like_SDR_c; cd05347
519441000352	NADP binding site [chemical binding]; other site
519441000353	homodimer interface [polypeptide binding]; other site
519441000354	active site
519441000355	5-keto-4-deoxyuronate isomerase; Provisional; Region: PRK00924
519441000356	glycerol-3-phosphate transporter ATP-binding subunit; Provisional; Region: ugpC; PRK11650
519441000357	The N-terminal ATPase domain of the maltose transporter, MalK; Region: ABC_MalK_N; cd03301
519441000358	Walker A/P-loop; other site
519441000359	ATP binding site [chemical binding]; other site
519441000360	Q-loop/lid; other site
519441000361	ABC transporter signature motif; other site
519441000362	Walker B; other site
519441000363	D-loop; other site
519441000364	H-loop/switch region; other site
519441000365	ABC-type polysaccharide transport system, permease component [Carbohydrate transport and metabolism]; Region: LplB; COG4209
519441000366	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
519441000367	dimer interface [polypeptide binding]; other site
519441000368	conserved gate region; other site
519441000369	putative PBP binding loops; other site
519441000370	ABC-ATPase subunit interface; other site
519441000371	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
519441000372	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
519441000373	dimer interface [polypeptide binding]; other site
519441000374	conserved gate region; other site
519441000375	ABC-ATPase subunit interface; other site
519441000376	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
519441000377	Alginate Lyase A1-III; enzymatically depolymerizes alginate, a complex copolymer of beta-D-mannuronate and alpha-L-guluronate, by cleaving the beta-(1,4) glycosidic bond; Region: AlgLyase; cl00179
519441000378	Heparinase II/III-like protein; Region: Hepar_II_III; pfam07940
519441000379	Glycosaminoglycan (GAG) polysaccharide lyase family. This family consists of a group of secreted bacterial lyase enzymes capable of acting on glycosaminoglycans, such as hyaluronan and chondroitin, in the extracellular matrix of host tissues; Region: GAG_Lyase; cd01083
519441000380	substrate binding site [chemical binding]; other site
519441000381	catalytic residues [active]
519441000382	Arylsulfatase A and related enzymes [Inorganic ion transport and metabolism]; Region: AslA; COG3119
519441000383	Sulfatase; Region: Sulfatase; cl17466
519441000384	Glycosyl Hydrolase Family 88; Region: Glyco_hydro_88; pfam07470
519441000385	OsmC-like protein; Region: OsmC; pfam02566
519441000386	Solo B3/4 domain (OB-fold DNA/RNA-binding) of Phe-aaRS-beta [General function prediction only]; Region: COG3382
519441000387	Family A polymerase primarily fills DNA gaps that arise during DNA repair, recombination and replication; Region: DNA_pol_A; cl02626
519441000388	B3/4 domain; Region: B3_4; pfam03483
519441000389	GTPase Era; Reviewed; Region: era; PRK00089
519441000390	E. coli Ras-like protein (Era) is a multifunctional GTPase; Region: Era; cd04163
519441000391	G1 box; other site
519441000392	GTP/Mg2+ binding site [chemical binding]; other site
519441000393	Switch I region; other site
519441000394	G2 box; other site
519441000395	Switch II region; other site
519441000396	G3 box; other site
519441000397	G4 box; other site
519441000398	G5 box; other site
519441000399	Phosphoglycerate kinase (PGK) is a monomeric enzyme which catalyzes the transfer of the high-energy phosphate group of 1,3-bisphosphoglycerate to ADP, forming ATP and 3-phosphoglycerate. This reaction represents the first of the two substrate-level...; Region: Phosphoglycerate_kinase; cd00318
519441000400	Phosphoglycerate kinase; Region: PGK; pfam00162
519441000401	substrate binding site [chemical binding]; other site
519441000402	hinge regions; other site
519441000403	ADP binding site [chemical binding]; other site
519441000404	catalytic site [active]
519441000405	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
519441000406	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
519441000407	Walker A/P-loop; other site
519441000408	ATP binding site [chemical binding]; other site
519441000409	Q-loop/lid; other site
519441000410	ABC transporter signature motif; other site
519441000411	Walker B; other site
519441000412	D-loop; other site
519441000413	H-loop/switch region; other site
519441000414	ABC-type uncharacterized transport system, permease component [General function prediction only]; Region: COG4587
519441000415	Class I aldolases; Region: Aldolase_Class_I; cl17187
519441000416	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
519441000417	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
519441000418	dimer interface [polypeptide binding]; other site
519441000419	conserved gate region; other site
519441000420	putative PBP binding loops; other site
519441000421	ABC-ATPase subunit interface; other site
519441000422	ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177
519441000423	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
519441000424	conserved gate region; other site
519441000425	dimer interface [polypeptide binding]; other site
519441000426	putative PBP binding loops; other site
519441000427	ABC-ATPase subunit interface; other site
519441000428	carbohydrate ABC transporter substrate-binding protein, CPR_0540 family; Region: bind_CPR_0540; TIGR03850
519441000429	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
519441000430	Lacto-N-biose phosphorylase; Region: Lact_bio_phlase; pfam09508
519441000431	1,3-beta-galactosyl-N-acetylhexosamine phosphorylase; Region: TIGR02336
519441000432	putative sugar isomerase, AgaS family; Region: agaS_fam; TIGR02815
519441000433	SIS (Sugar ISomerase) domain repeat 1 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_1; cd05008
519441000434	dimer interface [polypeptide binding]; other site
519441000435	active site
519441000436	SIS domain. SIS (Sugar ISomerase) domains are found in many phosphosugar isomerases and phosphosugar binding proteins. SIS domains are also found in proteins that regulate the expression of genes involved in synthesis of phosphosugars; Region: SIS; cl00389
519441000437	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cd00006
519441000438	active pocket/dimerization site; other site
519441000439	active site
519441000440	phosphorylation site [posttranslational modification]
519441000441	PTS system mannose/fructose/sorbose family IID component; Region: EIID-AGA; pfam03613
519441000442	PTS system sorbose-specific iic component; Region: EII-Sor; pfam03609
519441000443	PTS_IIB, PTS system, Mannose/sorbose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_man; cd00001
519441000444	active site
519441000445	phosphorylation site [posttranslational modification]
519441000446	Immunoglobulin A1 protease; Region: Peptidase_S6; pfam02395
519441000447	Sialidases or neuraminidases function to bind and hydrolyze terminal sialic acid residues from various glycoconjugates as well as playing roles in pathogenesis, bacterial nutrition and cellular interactions. They have a six-bladed, beta-propeller fold...; Region: Sialidase; cl17698
519441000448	Sodium:dicarboxylate symporter family; Region: SDF; pfam00375
519441000449	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
519441000450	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
519441000451	haloacid dehalogenase-like hydrolase; Region: Hydrolase_3; pfam08282
519441000452	active site
519441000453	motif I; other site
519441000454	motif II; other site
519441000455	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cl17915
519441000456	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
519441000457	Response regulator receiver domain; Region: Response_reg; pfam00072
519441000458	active site
519441000459	phosphorylation site [posttranslational modification]
519441000460	intermolecular recognition site; other site
519441000461	dimerization interface [polypeptide binding]; other site
519441000462	LrgA family; Region: LrgA; pfam03788
519441000463	Putative effector of murein hydrolase [Cell envelope biogenesis, outer membrane]; Region: LrgB; COG1346
519441000464	Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group...; Region: Cyt_C5_DNA_methylase; cd00315
519441000465	C-5 cytosine-specific DNA methylase; Region: DNA_methylase; pfam00145
519441000466	cofactor binding site; other site
519441000467	DNA binding site [nucleotide binding]
519441000468	substrate interaction site [chemical binding]; other site
519441000469	Peptidase domain in the S8 and S53 families; Region: Peptidases_S8_S53; cl10459
519441000470	catalytic residues [active]
519441000471	Autotransporter-associated beta strand repeat; Region: Autotrns_rpt; cl15373
519441000472	YadA-like, left-handed beta-roll; Region: LbR_YadA-like; cd12820
519441000473	trimer interface [polypeptide binding]; other site
519441000474	YadA-like, left-handed beta-roll; Region: LbR_YadA-like; cd12820
519441000475	trimer interface [polypeptide binding]; other site
519441000476	Haemagglutinin; Region: HIM; pfam05662
519441000477	Haemagglutinin; Region: HIM; pfam05662
519441000478	YadA-like C-terminal region; Region: YadA; pfam03895
519441000479	YadA-like, left-handed beta-roll; Region: LbR_YadA-like; cd12820
519441000480	trimer interface [polypeptide binding]; other site
519441000481	YadA-like, left-handed beta-roll; Region: LbR_YadA-like; cd12820
519441000482	trimer interface [polypeptide binding]; other site
519441000483	Autotransporter adhesin [Intracellular trafficking and secretion / Extracellular structures]; Region: Hia; COG5295
519441000484	Left-handed beta-roll, including virulence factors and various other proteins; Region: LbR-like; cl17507
519441000485	Haemagglutinin; Region: HIM; pfam05662
519441000486	Haemagglutinin; Region: HIM; pfam05662
519441000487	YadA-like C-terminal region; Region: YadA; pfam03895
519441000488	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
519441000489	ligand binding site [chemical binding]; other site
519441000490	Left-handed beta-roll, including virulence factors and various other proteins; Region: LbR-like; cl17507
519441000491	trimer interface [polypeptide binding]; other site
519441000492	YadA-like, left-handed beta-roll; Region: LbR_YadA-like; cd12820
519441000493	trimer interface [polypeptide binding]; other site
519441000494	YadA-like, left-handed beta-roll; Region: LbR_YadA-like; cd12820
519441000495	trimer interface [polypeptide binding]; other site
519441000496	Left-handed beta-roll, including virulence factors and various other proteins; Region: LbR-like; cl17507
519441000497	Haemagglutinin; Region: HIM; pfam05662
519441000498	YadA-like C-terminal region; Region: YadA; pfam03895
519441000499	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
519441000500	ligand binding site [chemical binding]; other site
519441000501	potential frameshift: common BLAST hit: gi|113460623|ref|YP_718689.1| cell-surface large adhesin
519441000502	Left-handed beta-roll, including virulence factors and various other proteins; Region: LbR-like; cl17507
519441000503	trimer interface [polypeptide binding]; other site
519441000504	Haemagglutinin; Region: HIM; pfam05662
519441000505	Left-handed beta-roll, including virulence factors and various other proteins; Region: LbR-like; cl17507
519441000506	Haemagglutinin; Region: HIM; pfam05662
519441000507	Haemagglutinin; Region: HIM; pfam05662
519441000508	YadA-like C-terminal region; Region: YadA; pfam03895
519441000509	YadA-like, left-handed beta-roll; Region: LbR_YadA-like; cd12820
519441000510	trimer interface [polypeptide binding]; other site
519441000511	YadA-like, left-handed beta-roll; Region: LbR_YadA-like; cd12820
519441000512	trimer interface [polypeptide binding]; other site
519441000513	YadA-like C-terminal region; Region: YadA; pfam03895
519441000514	YadA-like, left-handed beta-roll; Region: LbR_YadA-like; cd12820
519441000515	trimer interface [polypeptide binding]; other site
519441000516	Haemagglutinin; Region: HIM; pfam05662
519441000517	YadA-like C-terminal region; Region: YadA; pfam03895
519441000518	Left-handed beta-roll, including virulence factors and various other proteins; Region: LbR-like; cl17507
519441000519	trimer interface [polypeptide binding]; other site
519441000520	Haemagglutinin; Region: HIM; pfam05662
519441000521	YadA-like, left-handed beta-roll; Region: LbR_YadA-like; cd12820
519441000522	trimer interface [polypeptide binding]; other site
519441000523	YadA-like, left-handed beta-roll; Region: LbR_YadA-like; cd12820
519441000524	trimer interface [polypeptide binding]; other site
519441000525	Haemagglutinin; Region: HIM; pfam05662
519441000526	YadA-like C-terminal region; Region: YadA; pfam03895
519441000527	arginine deiminase; Provisional; Region: PRK01388
519441000528	ornithine carbamoyltransferase; Validated; Region: PRK02102
519441000529	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
519441000530	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
519441000531	carbamate kinase; Reviewed; Region: PRK12686
519441000532	AAK_CK: Carbamate kinase (CK) catalyzes both the ATP-phosphorylation of carbamate and carbamoyl phosphate (CP) utilization with the production of ATP from ADP and CP. Both CK (this CD) and nonhomologous CP synthetase synthesize carbamoyl phosphate, an...; Region: AAK_CK; cd04235
519441000533	putative substrate binding site [chemical binding]; other site
519441000534	nucleotide binding site [chemical binding]; other site
519441000535	nucleotide binding site [chemical binding]; other site
519441000536	homodimer interface [polypeptide binding]; other site
519441000537	Predicted membrane protein [Function unknown]; Region: COG1288
519441000538	Peptidase family C69; Region: Peptidase_C69; cl17793
519441000539	Immunoglobulin A1 protease; Region: Peptidase_S6; pfam02395
519441000540	Immunoglobulin A1 protease; Region: Peptidase_S6; pfam02395
519441000541	S12-like family, 30S ribosomal protein S12 subfamily; S12 is located at the interface of the large and small ribosomal subunits of prokaryotes, chloroplasts and mitochondria, where it plays an important role in both tRNA and ribosomal subunit...; Region: Ribosomal_S12; cd03368
519441000542	S17 interaction site [polypeptide binding]; other site
519441000543	S8 interaction site; other site
519441000544	16S rRNA interaction site [nucleotide binding]; other site
519441000545	streptomycin interaction site [chemical binding]; other site
519441000546	23S rRNA interaction site [nucleotide binding]; other site
519441000547	aminoacyl-tRNA interaction site (A-site) [nucleotide binding]; other site
519441000548	30S ribosomal protein S7; Validated; Region: PRK05302
519441000549	elongation factor G; Reviewed; Region: PRK00007
519441000550	Elongation factor G (EF-G) family involved in both the elongation and ribosome recycling phases of protein synthesis; Region: EF-G; cd01886
519441000551	G1 box; other site
519441000552	putative GEF interaction site [polypeptide binding]; other site
519441000553	GTP/Mg2+ binding site [chemical binding]; other site
519441000554	Switch I region; other site
519441000555	G2 box; other site
519441000556	G3 box; other site
519441000557	Switch II region; other site
519441000558	G4 box; other site
519441000559	G5 box; other site
519441000560	EFG_mtEFG_II: this subfamily represents the domain II of elongation factor G (EF-G) in bacteria and, the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2)_like proteins found in eukaryotes. During the process of peptide synthesis...; Region: EFG_mtEFG_II; cd04088
519441000561	EFG_mtEFG1_IV: domains similar to domain IV of the bacterial translational elongation factor (EF) EF-G. Included in this group is a domain of mitochondrial Elongation factor G1 (mtEFG1) proteins homologous to domain IV of EF-G. Eukaryotic cells harbor 2...; Region: EFG_mtEFG1_IV; cd01434
519441000562	EFG_mtEFG_C: domains similar to the C-terminal domain of the bacterial translational elongation factor (EF) EF-G.  Included in this group is the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2) proteins. Eukaryotic cells harbor 2...; Region: EFG_mtEFG_C; cd03713
519441000563	elongation factor Tu; Reviewed; Region: PRK00049
519441000564	Elongation Factor Tu (EF-Tu) GTP-binding proteins; Region: EF_Tu; cd01884
519441000565	G1 box; other site
519441000566	GEF interaction site [polypeptide binding]; other site
519441000567	GTP/Mg2+ binding site [chemical binding]; other site
519441000568	Switch I region; other site
519441000569	G2 box; other site
519441000570	G3 box; other site
519441000571	Switch II region; other site
519441000572	G4 box; other site
519441000573	G5 box; other site
519441000574	EFTU_II: Elongation factor Tu domain II. Elongation factors Tu (EF-Tu) are three-domain GTPases with an essential function in the elongation phase of mRNA translation. The GTPase center of EF-Tu is in the N-terminal domain (domain I), also known as the...; Region: EFTU_II; cd03697
519441000575	Domain III of elongation factor (EF) Tu. Ef-Tu consists of three structural domains, designated I, II and III. Domain III adopts a beta barrel structure. Domain III is involved in binding to both charged tRNA and binding to elongation factor Ts (EF-Ts); Region: EFTU_III; cd03707
519441000576	Antibiotic Binding Site [chemical binding]; other site
519441000577	30S ribosomal protein S10; Reviewed; Region: rpsJ; PRK00596
519441000578	50S ribosomal protein L3; Validated; Region: rplC; PRK00001
519441000579	50S ribosomal protein L4; Provisional; Region: rplD; PRK05319
519441000580	50S ribosomal protein L23; Reviewed; Region: rplW; PRK05738
519441000581	Na+/alanine symporter [Amino acid transport and metabolism]; Region: AlsT; COG1115
519441000582	Sodium:alanine symporter family; Region: Na_Ala_symp; cl00548
519441000583	Transcriptional antiterminator [Transcription]; Region: BglG; COG3711
519441000584	HTH domain; Region: HTH_11; cl17392
519441000585	Mga helix-turn-helix domain; Region: Mga; pfam05043
519441000586	PRD domain; Region: PRD; pfam00874
519441000587	PTS_IIB_bgl_like: the PTS (phosphotransferase system) IIB domain of a family of sensory systems composed of a membrane-bound sugar-sensor (similar to BglF) and a transcription antiterminator (similar to BglG) which regulate expression of genes involved...; Region: PTS_IIB_bgl_like; cd05568
519441000588	active site
519441000589	P-loop; other site
519441000590	phosphorylation site [posttranslational modification]
519441000591	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2; Region: PTS_EIIA_2; pfam00359
519441000592	active site
519441000593	phosphorylation site [posttranslational modification]
519441000594	PTS_IIA, PTS system, lactose/cellobiose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_lac; cd00215
519441000595	methionine cluster; other site
519441000596	active site
519441000597	phosphorylation site [posttranslational modification]
519441000598	metal binding site [ion binding]; metal-binding site
519441000599	PTS_IIB_chitobiose_lichenan: subunit IIB of enzyme II (EII) of the N,N-diacetylchitobiose-specific and lichenan-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In these systems, EII is either a lichenan- or an N; Region: PTS_IIB_chitobiose_lichenan; cd05564
519441000600	active site
519441000601	P-loop; other site
519441000602	phosphorylation site [posttranslational modification]
519441000603	Phosphotransferase system cellobiose-specific component IIC [Carbohydrate transport and metabolism]; Region: CelB; COG1455
519441000604	cellobiose phosphotransferase system IIC component; Reviewed; Region: celD; PRK09592
519441000605	Domain of unknown function (DUF3284); Region: DUF3284; pfam11687
519441000606	Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase [Carbohydrate transport and metabolism]; Region: BglB; COG2723
519441000607	beta-galactosidase; Region: BGL; TIGR03356
519441000608	Pertactin-like passenger domains (virulence factors) of autotransporter proteins of the type V secretion system. Autotransporters are proteins used by Gram-negative bacteria to transport proteins across their outer membranes. The C-terminal (beta) domain...; Region: PL_Passenger_AT; cd00253
519441000609	outer membrane autotransporter barrel domain; Region: autotrans_barl; TIGR01414
519441000610	Autotransporter beta-domain; Region: Autotransporter; pfam03797
519441000611	Type I periplasmic ligand-binding domain of uncharacterized ABC-type transport systems that are predicted to be involved in the uptake of amino acids, peptides, or inorganic ions; Region: PBP1_ABC_uncharacterized_transporter; cd06325
519441000612	Periplasmic binding protein domain; Region: Peripla_BP_4; pfam13407
519441000613	zinc binding site [ion binding]; other site
519441000614	putative ligand binding site [chemical binding]; other site
519441000615	Transmembrane subunit (TM) of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which are involved in the uptake of branched-chain amino acids (AAs), as well as TMs of transporters involved in the uptake of...; Region: TM_PBP1_branched-chain-AA_like; cd06574
519441000616	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
519441000617	TM-ABC transporter signature motif; other site
519441000618	ABC-type uncharacterized transport system, ATPase component [General function prediction only]; Region: PhnK; COG1101
519441000619	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
519441000620	Walker A/P-loop; other site
519441000621	ATP binding site [chemical binding]; other site
519441000622	Q-loop/lid; other site
519441000623	ABC transporter signature motif; other site
519441000624	Walker B; other site
519441000625	D-loop; other site
519441000626	H-loop/switch region; other site
519441000627	Tyrosine phosphatase family; Region: Y_phosphatase2; pfam03162
519441000628	PTS_IIB_ascorbate: subunit IIB of enzyme II (EII) of the L-ascorbate-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is an L-ascorbate-specific permease with two cytoplasmic subunits (IIA and IIB) and a...; Region: PTS_IIB_ascorbate; cd05563
519441000629	active site
519441000630	P-loop; other site
519441000631	phosphorylation site [posttranslational modification]
519441000632	glutamyl-tRNA synthetase; Reviewed; Region: gltX; PRK01406
519441000633	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
519441000634	active site
519441000635	HIGH motif; other site
519441000636	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
519441000637	active site
519441000638	KMSKS motif; other site
519441000639	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
519441000640	Ribosomal protein S2 (RPS2), involved in formation of the translation initiation complex, where it might contact the messenger RNA and several components of the ribosome. It has been shown that in Escherichia coli RPS2 is essential for the binding of...; Region: RPS2; cd01425
519441000641	rRNA interaction site [nucleotide binding]; other site
519441000642	S8 interaction site; other site
519441000643	putative laminin-1 binding site; other site
519441000644	elongation factor Ts; Provisional; Region: tsf; PRK09377
519441000645	UBA/TS-N domain; Region: UBA; pfam00627
519441000646	Elongation factor TS; Region: EF_TS; pfam00889
519441000647	Elongation factor TS; Region: EF_TS; pfam00889
519441000648	UMP kinase (UMPK)-Ec, the microbial/chloroplast uridine monophosphate kinase (uridylate kinase) enzyme that catalyzes UMP phosphorylation and plays a key role in pyrimidine nucleotide biosynthesis; regulation of this process is via feed-back control and...; Region: AAK_UMPK-PyrH-Ec; cd04254
519441000649	putative nucleotide binding site [chemical binding]; other site
519441000650	uridine monophosphate binding site [chemical binding]; other site
519441000651	homohexameric interface [polypeptide binding]; other site
519441000652	ribosome recycling factor; Reviewed; Region: frr; PRK00083
519441000653	Ribosome recycling factor (RRF). Ribosome recycling factor dissociates the posttermination complex, composed of the ribosome, deacylated tRNA, and mRNA, after termination of translation.  Thus ribosomes are "recycled" and ready for another...; Region: RRF; cd00520
519441000654	hinge region; other site
519441000655	rod shape-determining protein MreB; Provisional; Region: PRK13930
519441000656	MreB and similar proteins; Region: MreB_like; cd10225
519441000657	nucleotide binding site [chemical binding]; other site
519441000658	Mg binding site [ion binding]; other site
519441000659	putative protofilament interaction site [polypeptide binding]; other site
519441000660	RodZ interaction site [polypeptide binding]; other site
519441000661	Transposase IS200 like; Region: Y1_Tnp; pfam01797
519441000662	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
519441000663	TPR motif; other site
519441000664	TPR repeat; Region: TPR_11; pfam13414
519441000665	binding surface
519441000666	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
519441000667	active site
519441000668	phosphorylation site [posttranslational modification]
519441000669	ABC-type metal ion transport system, periplasmic component/surface adhesin [Inorganic ion transport and metabolism]; Region: LraI; COG0803
519441000670	Helical backbone metal receptor (TroA-like domain). These proteins have been shown to function in the ABC transport of ferric siderophores and metal ions such as Mn2+, Fe3+, Cu2+ and/or Zn2+.  Their ligand binding site is formed in the interface between...; Region: TroA-like; cl00262
519441000671	intersubunit interface [polypeptide binding]; other site
519441000672	ABC-type Mn/Zn transport systems, ATPase component [Inorganic ion transport and metabolism]; Region: ZnuC; COG1121
519441000673	ATP-binding cassette domain of the metal-type transporters; Region: ABC_Metallic_Cations; cd03235
519441000674	ABC-type Mn2+/Zn2+ transport systems, permease components [Inorganic ion transport and metabolism]; Region: ZnuB; COG1108
519441000675	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
519441000676	ABC-ATPase subunit  interface; other site
519441000677	dimer interface [polypeptide binding]; other site
519441000678	putative PBP binding regions; other site
519441000679	ABC-type Mn2+/Zn2+ transport systems, permease components [Inorganic ion transport and metabolism]; Region: ZnuB; COG1108
519441000680	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
519441000681	ABC-ATPase subunit  interface; other site
519441000682	dimer interface [polypeptide binding]; other site
519441000683	putative PBP binding regions; other site
519441000684	Left-handed beta-roll, including virulence factors and various other proteins; Region: LbR-like; cl17507
519441000685	trimer interface [polypeptide binding]; other site
519441000686	YadA-like, left-handed beta-roll; Region: LbR_YadA-like; cd12820
519441000687	trimer interface [polypeptide binding]; other site
519441000688	YadA-like, left-handed beta-roll; Region: LbR_YadA-like; cd12820
519441000689	trimer interface [polypeptide binding]; other site
519441000690	Left-handed beta-roll, including virulence factors and various other proteins; Region: LbR-like; cl17507
519441000691	YadA-like C-terminal region; Region: YadA; pfam03895
519441000692	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
519441000693	ligand binding site [chemical binding]; other site
519441000694	YadA-like, left-handed beta-roll; Region: LbR_YadA-like; cd12820
519441000695	trimer interface [polypeptide binding]; other site
519441000696	YadA-like C-terminal region; Region: YadA; pfam03895
519441000697	(R)-2-Hydroxyglutarate Dehydrogenase and related dehydrogenases, NAD-binding and catalytic domains; Region: HGDH_like; cd12184
519441000698	Lactate dehydrogenase and related dehydrogenases [Energy production and conversion / Coenzyme metabolism / General function prediction only]; Region: LdhA; COG1052
519441000699	putative homodimer interface [polypeptide binding]; other site
519441000700	putative ligand binding site [chemical binding]; other site
519441000701	putative NAD binding site [chemical binding]; other site
519441000702	catalytic site [active]
519441000703	Membrane transport protein; Region: Mem_trans; cl09117
519441000704	Chromate transporter; Region: Chromate_transp; pfam02417
519441000705	Chromate transporter; Region: Chromate_transp; pfam02417
519441000706	hypothetical protein; Validated; Region: PRK00153
519441000707	valyl-tRNA synthetase; Reviewed; Region: valS; PRK05729
519441000708	catalytic core domain of valyl-tRNA synthetases; Region: ValRS_core; cd00817
519441000709	HIGH motif; other site
519441000710	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
519441000711	catalytic core domain of valyl-tRNA synthetases; Region: ValRS_core; cd00817
519441000712	active site
519441000713	KMSKS motif; other site
519441000714	Anticodon-binding domain of valyl tRNA synthetases; Region: Anticodon_Ia_Val; cd07962
519441000715	tRNA binding surface [nucleotide binding]; other site
519441000716	anticodon binding site; other site
519441000717	Valyl tRNA synthetase tRNA binding arm; Region: Val_tRNA-synt_C; pfam10458
519441000718	Outer membrane protein and related peptidoglycan-associated (lipo)proteins [Cell envelope biogenesis, outer membrane]; Region: OmpA; COG2885
519441000719	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
519441000720	ligand binding site [chemical binding]; other site
519441000721	Type III pantothenate kinase; Region: Pan_kinase; cl17198
519441000722	Bacterial type II and III secretion system protein; Region: Secretin; pfam00263
519441000723	Type II secretory pathway, component PulF [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PulF; COG1459
519441000724	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
519441000725	YadA-like C-terminal region; Region: YadA; pfam03895
519441000726	Outer membrane protein and related peptidoglycan-associated (lipo)proteins [Cell envelope biogenesis, outer membrane]; Region: OmpA; COG2885
519441000727	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
519441000728	ligand binding site [chemical binding]; other site
519441000729	Peptide methionine sulfoxide reductase [Posttranslational modification, protein turnover, chaperones]; Region: MsrA; COG0225
519441000730	methionine sulfoxide reductase B; Provisional; Region: PRK00222
519441000731	SelR domain; Region: SelR; pfam01641
519441000732	V-type ATP synthase subunit I; Validated; Region: PRK05771
519441000733	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
519441000734	putative substrate translocation pore; other site
519441000735	V-type ATP synthase subunit K; Validated; Region: PRK06558
519441000736	ATP synthase subunit C; Region: ATP-synt_C; pfam00137
519441000737	ATP synthase subunit C; Region: ATP-synt_C; pfam00137
519441000738	Archaeal/vacuolar-type H+-ATPase subunit E [Energy production and conversion]; Region: NtpE; COG1390
519441000739	V-type ATP synthase subunit E; Provisional; Region: PRK03963; cl17074
519441000740	Archaeal/vacuolar-type H+-ATPase subunit C [Energy production and conversion]; Region: NtpC; COG1527
519441000741	V-type ATP synthase subunit C; Provisional; Region: PRK01198; cl00660
519441000742	ATP synthase (F/14-kDa) subunit; Region: ATP-synt_F; cl00632
519441000743	V-type ATP synthase subunit A; Provisional; Region: PRK04192
519441000744	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
519441000745	V/A-type ATP synthase catalytic subunit A. These ATPases couple ATP hydrolysis to the build up of a H+ gradient, but V-type ATPases do not catalyze the reverse reaction.  The Vacuolar (V-type) ATPase is found in the membranes of vacuoles, the golgi...; Region: V_A-ATPase_A; cd01134
519441000746	Walker A motif/ATP binding site; other site
519441000747	Walker B motif; other site
519441000748	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
519441000749	V-type ATP synthase subunit B; Provisional; Region: PRK04196
519441000750	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
519441000751	V/A-type ATP synthase (non-catalytic) subunit B. These ATPases couple ATP hydrolysis to the build up of a H+ gradient, but V-type ATPases do not catalyze the reverse reaction. The Vacuolar (V-type) ATPase is found in the membranes of vacuoles, the golgi...; Region: V_A-ATPase_B; cd01135
519441000752	Walker A motif homologous position; other site
519441000753	Walker B motif; other site
519441000754	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
519441000755	V-type ATP synthase subunit D; Reviewed; Region: PRK00373
519441000756	glycerol-3-phosphate transporter ATP-binding subunit; Provisional; Region: ugpC; PRK11650
519441000757	The N-terminal ATPase domain of the maltose transporter, MalK; Region: ABC_MalK_N; cd03301
519441000758	Walker A/P-loop; other site
519441000759	ATP binding site [chemical binding]; other site
519441000760	Q-loop/lid; other site
519441000761	ABC transporter signature motif; other site
519441000762	Walker B; other site
519441000763	D-loop; other site
519441000764	H-loop/switch region; other site
519441000765	Domain of unknown function (DUF955); Region: DUF955; pfam06114
519441000766	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
519441000767	dimerization domain swap beta strand [polypeptide binding]; other site
519441000768	regulatory protein interface [polypeptide binding]; other site
519441000769	active site
519441000770	regulatory phosphorylation site [posttranslational modification]; other site
519441000771	transcription termination factor Rho; Provisional; Region: rho; PRK09376
519441000772	Rho termination factor, N-terminal domain; Region: Rho_N; cl06505
519441000773	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
519441000774	RNA binding site [nucleotide binding]; other site
519441000775	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
519441000776	Walker A motif; other site
519441000777	ATP binding site [chemical binding]; other site
519441000778	Walker B motif; other site
519441000779	Caulimovirus viroplasmin; Region: Cauli_VI; pfam01693
519441000780	RNase H is an endonuclease that cleaves the RNA strand of an RNA/DNA hybrid in a sequence non-specific manner; Region: RNase_H; cl14782
519441000781	active site
519441000782	Transposase zinc-binding domain; Region: Zn_Tnp_IS91; pfam14319
519441000783	Putative transposase; Region: Y2_Tnp; pfam04986
519441000784	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
519441000785	PTS system, glucose-specific IIBC component; Region: PTS-II-BC-glcB; TIGR02002
519441000786	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
519441000787	active site turn [active]
519441000788	phosphorylation site [posttranslational modification]
519441000789	formate--tetrahydrofolate ligase; Provisional; Region: PRK13505
519441000790	Formyltetrahydrofolate synthetase (FTHFS) catalyzes the ATP-dependent activation of formate ion via its addition to the N10 position of tetrahydrofolate. FTHFS is a highly expressed key enzyme in both the Wood-Ljungdahl pathway of autotrophic CO2...; Region: FTHFS; cd00477
519441000791	Potassium binding sites [ion binding]; other site
519441000792	Cesium cation binding sites [ion binding]; other site
519441000793	Mov34/MPN/PAD-1 family; Region: MPN_DUF2466; cd08071
519441000794	MPN+ (JAMM) motif; other site
519441000795	Zinc-binding site [ion binding]; other site
519441000796	PSP1 C-terminal conserved region; Region: PSP1; cl00770
519441000797	Predicted O-methyltransferase [General function prediction only]; Region: COG4123
519441000798	Methyltransferase domain; Region: Methyltransf_26; pfam13659
519441000799	Cupin domain; Region: Cupin_2; pfam07883
519441000800	Dephospho-CoA kinase [Coenzyme metabolism]; Region: CoaE; COG0237
519441000801	Dephospho-coenzyme A kinase (DPCK, EC 2.7.1.24) catalyzes the phosphorylation of dephosphocoenzyme A (dCoA) to yield CoA, which is the final step in CoA biosynthesis; Region: DPCK; cd02022
519441000802	CoA-binding site [chemical binding]; other site
519441000803	ATP-binding [chemical binding]; other site
519441000804	YihA (EngB) GTPase family; Region: YihA_EngB; cd01876
519441000805	G1 box; other site
519441000806	GTP/Mg2+ binding site [chemical binding]; other site
519441000807	Switch I region; other site
519441000808	G2 box; other site
519441000809	G3 box; other site
519441000810	Switch II region; other site
519441000811	G4 box; other site
519441000812	G5 box; other site
519441000813	Uncharacterized conserved protein [Function unknown]; Region: LemA; COG1704
519441000814	Predicted membrane protein (DUF2207); Region: DUF2207; pfam09972
519441000815	Predicted membrane protein (DUF2207); Region: DUF2207; pfam09972
519441000816	ABC-type spermidine/putrescine transport systems, ATPase components [Amino acid transport and metabolism]; Region: PotA; COG3842
519441000817	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
519441000818	Walker A/P-loop; other site
519441000819	ATP binding site [chemical binding]; other site
519441000820	Q-loop/lid; other site
519441000821	ABC transporter signature motif; other site
519441000822	Walker B; other site
519441000823	D-loop; other site
519441000824	H-loop/switch region; other site
519441000825	TOBE domain; Region: TOBE_2; pfam08402
519441000826	ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism]; Region: ThiP; COG1178
519441000827	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
519441000828	dimer interface [polypeptide binding]; other site
519441000829	conserved gate region; other site
519441000830	putative PBP binding loops; other site
519441000831	ABC-ATPase subunit interface; other site
519441000832	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
519441000833	dimer interface [polypeptide binding]; other site
519441000834	conserved gate region; other site
519441000835	putative PBP binding loops; other site
519441000836	ABC-ATPase subunit interface; other site
519441000837	ABC-type thiamine transport system, periplasmic component [Coenzyme metabolism]; Region: TbpA; COG4143
519441000838	ABC-type Fe3+ transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: AfuA; COG1840
519441000839	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
519441000840	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
519441000841	Walker A/P-loop; other site
519441000842	ATP binding site [chemical binding]; other site
519441000843	Q-loop/lid; other site
519441000844	ABC transporter signature motif; other site
519441000845	Walker B; other site
519441000846	D-loop; other site
519441000847	H-loop/switch region; other site
519441000848	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
519441000849	dimer interface [polypeptide binding]; other site
519441000850	conserved gate region; other site
519441000851	ABC-ATPase subunit interface; other site
519441000852	ABC-type metal ion transport system, periplasmic component/surface antigen [Inorganic ion transport and metabolism]; Region: NlpA; COG1464
519441000853	NLPA lipoprotein; Region: Lipoprotein_9; pfam03180
519441000854	haemagglutination activity domain; Region: Haemagg_act; pfam05860
519441000855	Adenine-specific DNA methylase [DNA replication, recombination, and repair]; Region: COG3392
519441000856	D12 class N6 adenine-specific DNA methyltransferase; Region: MethyltransfD12; cl17344
519441000857	50S ribosomal protein L28; Reviewed; Region: rpmB; PRK00359
519441000858	Bacterial fructose-1,6-bisphosphatase, glpX-encoded. A dimeric enzyme dependent on Mg(2+). glpX-encoded FPBase (FBPase class II) differs from other members of the inositol-phosphatase superfamily by permutation of secondary structure elements. The core...; Region: FBPase_glpX; cd01516
519441000859	Bacterial fructose-1,6-bisphosphatase, glpX-encoded; Region: FBPase_glpX; pfam03320
519441000860	putative active site [active]
519441000861	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
519441000862	Catalytic site [active]
519441000863	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
519441000864	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
519441000865	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
519441000866	Coenzyme A binding pocket [chemical binding]; other site
519441000867	Uncharacterized conserved protein [Function unknown]; Region: COG1543
519441000868	N-terminal catalytic domain of  alpha-amylase ( AmyC ) and similar proteins; Region: GH57N_AmyC_like; cd10792
519441000869	active site
519441000870	substrate binding site [chemical binding]; other site
519441000871	catalytic site [active]
519441000872	Domain of unknown function (DUF1957); Region: DUF1957; pfam09210
519441000873	Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes [Amino acid transport and metabolism]; Region: NifS; COG1104
519441000874	cysteine desulfurase NifS; Region: FeS_nifS; TIGR03402
519441000875	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
519441000876	catalytic residue [active]
519441000877	Protein of unknown function (DUF541); Region: SIMPL; cl01077
519441000878	Protein of unknown function (DUF541); Region: SIMPL; pfam04402
519441000879	Protein of unknown function (DUF541); Region: SIMPL; pfam04402
519441000880	pyruvate formate-lyase 1-activating enzyme; Region: PFLA; TIGR02493
519441000881	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
519441000882	FeS/SAM binding site; other site
519441000883	pyruvate:ferredoxin (flavodoxin) oxidoreductase, homodimeric; Region: pyruv_ox_red; TIGR02176
519441000884	Pyrimidine (PYR) binding domain of pyruvate ferredoxin oxidoreductase (PFOR), indolepyruvate ferredoxin oxidoreductase alpha subunit (IOR-alpha), and related proteins; Region: TPP_PYR_PFOR_IOR-alpha_like; cd07034
519441000885	dimer interface [polypeptide binding]; other site
519441000886	PYR/PP interface [polypeptide binding]; other site
519441000887	TPP binding site [chemical binding]; other site
519441000888	substrate binding site [chemical binding]; other site
519441000889	Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit [Energy production and conversion]; Region: PorG; COG1014
519441000890	Domain of unknown function; Region: EKR; cl11037
519441000891	4Fe-4S binding domain; Region: Fer4; pfam00037
519441000892	Thiamine pyrophosphate (TPP family), PFOR_PNO subfamily, TPP-binding module; composed of proteins similar to the single subunit pyruvate ferredoxin oxidoreductase (PFOR) of Desulfovibrio Africanus, present in bacteria and amitochondriate eukaryotes. This...; Region: TPP_PFOR_PNO; cd03377
519441000893	TPP-binding site [chemical binding]; other site
519441000894	dimer interface [polypeptide binding]; other site
519441000895	Left-handed beta-roll, including virulence factors and various other proteins; Region: LbR-like; cl17507
519441000896	trimer interface [polypeptide binding]; other site
519441000897	YadA-like, left-handed beta-roll; Region: LbR_YadA-like; cd12820
519441000898	trimer interface [polypeptide binding]; other site
519441000899	YadA-like, left-handed beta-roll; Region: LbR_YadA-like; cd12820
519441000900	trimer interface [polypeptide binding]; other site
519441000901	Left-handed beta-roll, including virulence factors and various other proteins; Region: LbR-like; cl17507
519441000902	trimer interface [polypeptide binding]; other site
519441000903	Haemagglutinin; Region: HIM; pfam05662
519441000904	Haemagglutinin; Region: HIM; pfam05662
519441000905	YadA-like C-terminal region; Region: YadA; pfam03895
519441000906	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
519441000907	ligand binding site [chemical binding]; other site
519441000908	Competence protein; Region: Competence; pfam03772
519441000909	ABC-type Mn/Zn transport systems, ATPase component [Inorganic ion transport and metabolism]; Region: ZnuC; COG1121
519441000910	ATP-binding cassette domain of the metal-type transporters; Region: ABC_Metallic_Cations; cd03235
519441000911	ABC-type Mn2+/Zn2+ transport systems, permease components [Inorganic ion transport and metabolism]; Region: ZnuB; COG1108
519441000912	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cl00462
519441000913	ABC-ATPase subunit  interface; other site
519441000914	dimer interface [polypeptide binding]; other site
519441000915	putative PBP binding regions; other site
519441000916	Protein of unknown function (DUF552); Region: DUF552; pfam04472
519441000917	GTPase CgtA; Reviewed; Region: obgE; PRK12297
519441000918	GTP1/OBG; Region: GTP1_OBG; pfam01018
519441000919	Obg GTPase; Region: Obg; cd01898
519441000920	G1 box; other site
519441000921	GTP/Mg2+ binding site [chemical binding]; other site
519441000922	Switch I region; other site
519441000923	G2 box; other site
519441000924	G3 box; other site
519441000925	Switch II region; other site
519441000926	G4 box; other site
519441000927	G5 box; other site
519441000928	Domain of unknown function (DUF1967); Region: DUF1967; cl07779
519441000929	tRNA delta(2)-isopentenylpyrophosphate transferase [Translation, ribosomal structure and biogenesis]; Region: MiaA; COG0324
519441000930	tRNA delta(2)-isopentenylpyrophosphate transferase; Reviewed; Region: miaA; PRK00091
519441000931	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
519441000932	active site
519441000933	phosphorylation site [posttranslational modification]
519441000934	Uridine monophosphate kinase (UMPK, EC 2.7.1.48), also known as uridine kinase or uridine-cytidine kinase (UCK), catalyzes the reversible phosphoryl transfer from ATP to uridine or cytidine to yield UMP or CMP. In the primidine nucleotide-salvage pathway; Region: UMPK; cd02023
519441000935	Uridine kinase [Nucleotide transport and metabolism]; Region: Udk; COG0572
519441000936	Sugar specificity; other site
519441000937	Pyrimidine base specificity; other site
519441000938	ATP-binding site [chemical binding]; other site
519441000939	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
519441000940	putative DNA binding site [nucleotide binding]; other site
519441000941	putative Zn2+ binding site [ion binding]; other site
519441000942	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
519441000943	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
519441000944	nucleotide binding site [chemical binding]; other site
519441000945	methyl-galactoside ABC transporter galactose-binding periplasmic protein MglB; Provisional; Region: PRK15395
519441000946	Periplasmic glucose/galactose-binding protein (GGBP) involved in chemotaxis towards, and active transport of, glucose and galactose in various bacterial species; Region: PBP1_GGBP; cd01539
519441000947	ligand binding site [chemical binding]; other site
519441000948	calcium binding site [ion binding]; other site
519441000949	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
519441000950	galactose/methyl galaxtoside transporter ATP-binding protein; Provisional; Region: PRK10982
519441000951	Walker A/P-loop; other site
519441000952	ATP binding site [chemical binding]; other site
519441000953	Q-loop/lid; other site
519441000954	ABC transporter signature motif; other site
519441000955	Walker B; other site
519441000956	D-loop; other site
519441000957	H-loop/switch region; other site
519441000958	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
519441000959	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
519441000960	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
519441000961	TM-ABC transporter signature motif; other site
519441000962	galactokinase; Provisional; Region: PRK05322
519441000963	Galactokinase galactose-binding signature; Region: GalKase_gal_bdg; pfam10509
519441000964	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
519441000965	GHMP kinases C terminal; Region: GHMP_kinases_C; pfam08544
519441000966	galactose mutarotase_like; Region: galactose_mutarotase_like; cd09019
519441000967	active site
519441000968	catalytic residues [active]
519441000969	UDP-glucose 4-epimerase [Cell envelope biogenesis, outer membrane]; Region: GalE; COG1087
519441000970	UDP-glucose 4 epimerase, subgroup 1, extended (e) SDRs; Region: UDP_G4E_1_SDR_e; cd05247
519441000971	NAD binding site [chemical binding]; other site
519441000972	homodimer interface [polypeptide binding]; other site
519441000973	active site
519441000974	substrate binding site [chemical binding]; other site
519441000975	galactose-1-phosphate uridylyltransferase; Provisional; Region: PRK05270
519441000976	Galactose-1-phosphate uridyl transferase, N-terminal domain; Region: GalP_UDP_transf; pfam01087
519441000977	Galactose-1-phosphate uridyl transferase, C-terminal domain; Region: GalP_UDP_tr_C; pfam02744
519441000978	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
519441000979	Sodium:dicarboxylate symporter family; Region: SDF; cl00573
519441000980	prolyl-tRNA synthetase; Provisional; Region: PRK09194
519441000981	Prolyl-tRNA synthetase (ProRS) class II core catalytic domain. ProRS is a homodimer. It is responsible for the attachment of proline to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ProRS_core_prok; cd00779
519441000982	dimer interface [polypeptide binding]; other site
519441000983	motif 1; other site
519441000984	active site
519441000985	motif 2; other site
519441000986	INS is an amino acid-editing domain inserted (INS) into the bacterial class II prolyl-tRNA synthetase (ProRS) however, this CD is not exclusively bacterial. It is also found at the N-terminus of the eukaryotic/archaea-like ProRS's of yeasts and...; Region: ProRS-INS; cd04334
519441000987	putative deacylase active site [active]
519441000988	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
519441000989	active site
519441000990	motif 3; other site
519441000991	ProRS Prolyl-anticodon binding domain, short version found predominantly in bacteria. ProRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding; Region: ProRS_anticodon_short; cd00861
519441000992	anticodon binding site; other site
519441000993	AzlC protein; Region: AzlC; cl00570
519441000994	This domain is found in peptide chain release factors; Region: PCRF; smart00937
519441000995	Protein chain release factor B [Translation, ribosomal structure and biogenesis]; Region: PrfB; COG1186
519441000996	RF-1 domain; Region: RF-1; pfam00472
519441000997	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
519441000998	active site
519441000999	Adenylosuccinate synthetase (AdSS) catalyzes the first step in the de novo biosynthesis of AMP. IMP and L-aspartate are conjugated in a two-step reaction accompanied by the hydrolysis of GTP to GDP in the presence of Mg2+. In the first step, the...; Region: AdSS; cd03108
519441001000	Adenylosuccinate synthetase; Region: Adenylsucc_synt; smart00788
519441001001	GDP-binding site [chemical binding]; other site
519441001002	ACT binding site; other site
519441001003	IMP binding site; other site
519441001004	Adenylosuccinate lyase [Nucleotide transport and metabolism]; Region: PurB; COG0015
519441001005	Adenylsuccinate lyase (ASL)_subgroup 2; Region: Adenylsuccinate_lyase_2; cd03302
519441001006	tetramer interface [polypeptide binding]; other site
519441001007	active site
519441001008	DNA polymerase III PolC; Validated; Region: polC; PRK00448
519441001009	polC_OBF: A subfamily of OB folds corresponding to the N-terminal OB-fold nucleic acid binding domain of Bacillus subtilis type C replicative DNA polymerase III alpha subunit (polC). Replication in B. subtilis and Staphylococcus aureus requires two...; Region: polC_OBF; cd04484
519441001010	generic binding surface II; other site
519441001011	generic binding surface I; other site
519441001012	Polymerase and Histidinol Phosphatase domain; Region: PHP; cl17102
519441001013	active site
519441001014	DEDDh 3'-5' exonuclease domain family; Region: DEDDh; cd06127
519441001015	active site
519441001016	substrate binding site [chemical binding]; other site
519441001017	catalytic site [active]
519441001018	Polymerase and Histidinol Phosphatase domain of alpha-subunit of bacterial polymerase III at PolC gene; Region: PHP_PolIIIA_POLC; cd07435
519441001019	Arginyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Region: ArgS; COG0018
519441001020	Arginyl tRNA synthetase N terminal domain; Region: Arg_tRNA_synt_N; pfam03485
519441001021	catalytic core domain of arginyl-tRNA synthetases; Region: ArgRS_core; cd00671
519441001022	active site
519441001023	HIGH motif; other site
519441001024	KMSK motif region; other site
519441001025	Anticodon-binding domain of arginyl tRNA synthetases; Region: Anticodon_Ia_Arg; cd07956
519441001026	tRNA binding surface [nucleotide binding]; other site
519441001027	anticodon binding site; other site
519441001028	bacterial Ribonuclease HII-like; Region: RNase_HII_bacteria_HII_like; cd07182
519441001029	RNA/DNA hybrid binding site [nucleotide binding]; other site
519441001030	active site
519441001031	S1_IF1: Translation Initiation Factor IF1, S1-like RNA-binding domain. IF1 contains an S1-like RNA-binding domain, which is found in a wide variety of RNA-associated proteins. Translation initiation includes a number of interrelated steps preceding the...; Region: S1_IF1; cd04451
519441001032	rRNA binding site [nucleotide binding]; other site
519441001033	predicted 30S ribosome binding site; other site
519441001034	50S ribosomal protein L36; Reviewed; Region: rpmJ; PRK00465
519441001035	30S ribosomal protein S13; Validated; Region: rpsM; PRK05179
519441001036	30S ribosomal protein S13; Region: bact_S13; TIGR03631
519441001037	30S ribosomal protein S11; Validated; Region: PRK05309
519441001038	30S ribosomal protein S4; Validated; Region: rpsD; PRK05327
519441001039	Ribosomal protein S4/S9 N-terminal domain; Region: Ribosomal_S4; pfam00163
519441001040	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
519441001041	RNA binding surface [nucleotide binding]; other site
519441001042	DNA-directed RNA polymerase subunit alpha; Provisional; Region: PRK05182
519441001043	N-terminal domain of the Alpha subunit of Bacterial RNA polymerase; Region: RNAP_alpha_NTD; cd06928
519441001044	alphaNTD homodimer interface [polypeptide binding]; other site
519441001045	alphaNTD - beta interaction site [polypeptide binding]; other site
519441001046	alphaNTD - beta' interaction site [polypeptide binding]; other site
519441001047	Bacterial RNA polymerase, alpha chain C terminal domain; Region: RNA_pol_A_CTD; pfam03118
519441001048	50S ribosomal protein L17; Validated; Region: rplQ; PRK05591
519441001049	Helix-turn-helix domain; Region: HTH_18; pfam12833
519441001050	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
519441001051	rRNA methylase, putative, group 3; Region: rRNA_methyl_3; TIGR00186
519441001052	RNA 2'-O ribose methyltransferase substrate binding; Region: SpoU_sub_bind; pfam08032
519441001053	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
519441001054	leucyl-tRNA synthetase; Validated; Region: leuS; PRK00390
519441001055	catalytic core domain of leucyl-tRNA synthetases; Region: LeuRS_core; cd00812
519441001056	HIGH motif; other site
519441001057	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
519441001058	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
519441001059	active site
519441001060	KMSKS motif; other site
519441001061	Anticodon-binding domain of bacterial and eukaryotic mitochondrial leucyl tRNA synthetases; Region: Anticodon_Ia_Leu_BEm; cd07958
519441001062	tRNA binding surface [nucleotide binding]; other site
519441001063	Carboxylate/Amino Acid/Amine Transporter; Region: 2A78; TIGR00950
519441001064	EamA-like transporter family; Region: EamA; pfam00892
519441001065	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
519441001066	ATP-binding cassette domain of multidrug resistance protein-like transporters; Region: ABCC_MRP_Like; cd03228
519441001067	putative bacteriocin export ABC transporter, lactococcin 972 group; Region: L_ocin_972_ABC; TIGR03608
519441001068	Walker A/P-loop; other site
519441001069	ATP binding site [chemical binding]; other site
519441001070	Q-loop/lid; other site
519441001071	ABC transporter signature motif; other site
519441001072	Walker B; other site
519441001073	D-loop; other site
519441001074	H-loop/switch region; other site
519441001075	DNA polymerase III, epsilon subunit and related 3'-5' exonucleases [DNA replication, recombination, and repair]; Region: DnaQ; COG0847
519441001076	DEDDh 3'-5' exonuclease domain family; Region: DEDDh; cd06127
519441001077	active site
519441001078	catalytic site [active]
519441001079	substrate binding site [chemical binding]; other site
519441001080	DNA polymerase III, epsilon subunit and related 3'-5' exonucleases [DNA replication, recombination, and repair]; Region: DnaQ; COG0847
519441001081	DEDDh 3'-5' exonuclease domain family; Region: DEDDh; cd06127
519441001082	active site
519441001083	catalytic site [active]
519441001084	substrate binding site [chemical binding]; other site
519441001085	ATP-NAD kinase; Region: NAD_kinase; pfam01513
519441001086	NAD kinase [Coenzyme metabolism]; Region: nadF; COG0061
519441001087	ATPase involved in DNA repair [DNA replication, recombination, and repair]; Region: RecN; COG0497
519441001088	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
519441001089	Walker A/P-loop; other site
519441001090	ATP binding site [chemical binding]; other site
519441001091	ATP-binding cassette domain of RecN; Region: ABC_RecN; cd03241
519441001092	ABC transporter signature motif; other site
519441001093	Walker B; other site
519441001094	D-loop; other site
519441001095	H-loop/switch region; other site
519441001096	Solute carrier 5 family, sodium/glucose transporters and related proteins; solute-binding domain; Region: SLC5sbd; cd10322
519441001097	Predicted symporter [General function prediction only]; Region: DhlC; COG4147
519441001098	Na binding site [ion binding]; other site
519441001099	Arylsulfatase A and related enzymes [Inorganic ion transport and metabolism]; Region: AslA; COG3119
519441001100	Sulfatase; Region: Sulfatase; pfam00884
519441001101	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
519441001102	tyrosine recombinase XerD; Region: recomb_XerD; TIGR02225
519441001103	active site
519441001104	DNA binding site [nucleotide binding]
519441001105	Int/Topo IB signature motif; other site
519441001106	Protein of unknown function (DUF1694); Region: DUF1694; cl02318
519441001107	UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Region: murA; TIGR01072
519441001108	UDP-N-acetylglucosamine enolpyruvyl transferase catalyzes enolpyruvyl transfer as part of the first step in the biosynthesis of peptidoglycan, a component of the bacterial cell wall. The reaction is phosphoenolpyruvate + UDP-N-acetyl-D-glucosamine =...; Region: UdpNAET; cd01555
519441001109	hinge; other site
519441001110	active site
519441001111	Left-handed beta-roll, including virulence factors and various other proteins; Region: LbR-like; cl17507
519441001112	trimer interface [polypeptide binding]; other site
519441001113	YadA-like, left-handed beta-roll; Region: LbR_YadA-like; cd12820
519441001114	trimer interface [polypeptide binding]; other site
519441001115	YadA-like, left-handed beta-roll; Region: LbR_YadA-like; cd12820
519441001116	trimer interface [polypeptide binding]; other site
519441001117	Left-handed beta-roll, including virulence factors and various other proteins; Region: LbR-like; cl17507
519441001118	trimer interface [polypeptide binding]; other site
519441001119	Haemagglutinin; Region: HIM; pfam05662
519441001120	Haemagglutinin; Region: HIM; pfam05662
519441001121	YadA-like C-terminal region; Region: YadA; pfam03895
519441001122	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
519441001123	ligand binding site [chemical binding]; other site
519441001124	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
519441001125	Walker A/P-loop; other site
519441001126	ATP binding site [chemical binding]; other site
519441001127	ABC transporter; Region: ABC_tran; pfam00005
519441001128	Q-loop/lid; other site
519441001129	ABC transporter signature motif; other site
519441001130	Walker B; other site
519441001131	D-loop; other site
519441001132	H-loop/switch region; other site
519441001133	Predicted transcriptional regulators [Transcription]; Region: COG1725
519441001134	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
519441001135	DNA-binding site [nucleotide binding]; DNA binding site
519441001136	DNA polymerase III, delta subunit; Region: holA; TIGR01128
519441001137	Asp-tRNAAsn/Glu-tRNAGln amidotransferase C subunit [Translation, ribosomal structure and biogenesis]; Region: GatC; COG0721
519441001138	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases [Translation, ribosomal structure and biogenesis]; Region: GatA; COG0154
519441001139	aspartyl/glutamyl-tRNA amidotransferase subunit A; Reviewed; Region: gatA; PRK00012
519441001140	aspartyl/glutamyl-tRNA amidotransferase subunit B; Validated; Region: gatB; PRK05477
519441001141	GatB/GatE catalytic domain; Region: GatB_N; pfam02934
519441001142	GatB domain; Region: GatB_Yqey; smart00845
519441001143	stage V sporulation protein D; Region: spoVD_pbp; TIGR02214
519441001144	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
519441001145	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
519441001146	PASTA domain of PBP2x-like proteins, second repeat. Penicillin-binding proteins (PBPs) are the major targets for beta-lactam antibiotics, like penicillins and cephalosporins. Beta-lactam antibiotics specifically inhibit transpeptidase activity by...; Region: PASTA_Pbp2x-like_2; cd06575
519441001147	primosome assembly protein PriA; Validated; Region: PRK05580
519441001148	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
519441001149	ATP binding site [chemical binding]; other site
519441001150	putative Mg++ binding site [ion binding]; other site
519441001151	helicase superfamily c-terminal domain; Region: HELICc; smart00490
519441001152	Polypeptide or peptide deformylase; a family of metalloenzymes that catalyzes the removal of the N-terminal formyl group in a growing polypeptide chain following translation initiation during protein synthesis in prokaryotes. These enzymes utilize Fe(II)...; Region: Pep_deformylase; cd00487
519441001153	active site
519441001154	catalytic residues [active]
519441001155	metal binding site [ion binding]; metal-binding site
519441001156	methionyl-tRNA formyltransferase; Reviewed; Region: fmt; PRK00005
519441001157	Methionyl-tRNA formyltransferase, N-terminal hydrolase domain; Region: FMT_core_Met-tRNA-FMT_N; cd08646
519441001158	putative active site [active]
519441001159	substrate binding site [chemical binding]; other site
519441001160	putative cosubstrate binding site; other site
519441001161	catalytic site [active]
519441001162	C-terminal domain of Formyltransferase and other enzymes; Region: Met_tRNA_FMT_C; cd08704
519441001163	substrate binding site [chemical binding]; other site
519441001164	redox-sensing transcriptional repressor Rex; Provisional; Region: PRK05472
519441001165	Putative DNA-binding protein N-terminus; Region: Put_DNA-bind_N; pfam06971
519441001166	CoA binding domain; Region: CoA_binding; pfam02629
519441001167	5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase [Coenzyme metabolism]; Region: FolD; COG0190
519441001168	Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain; Region: THF_DHG_CYH; pfam00763
519441001169	NADP binding domain of methylene-tetrahydrofolate dehydrogenase/cyclohydrolase; Region: NAD_bind_m-THF_DH_Cyclohyd; cd01080
519441001170	homodimer interface [polypeptide binding]; other site
519441001171	NADP binding site [chemical binding]; other site
519441001172	substrate binding site [chemical binding]; other site
519441001173	Domain of unknown function DUF21; Region: DUF21; pfam01595
519441001174	Hemolysins and related proteins containing CBS domains [General function prediction only]; Region: TlyC; COG1253
519441001175	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
519441001176	Transporter associated domain; Region: CorC_HlyC; smart01091
519441001177	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
519441001178	active site
519441001179	Helix-turn-helix domain; Region: HTH_31; pfam13560
519441001180	non-specific DNA binding site [nucleotide binding]; other site
519441001181	salt bridge; other site
519441001182	sequence-specific DNA binding site [nucleotide binding]; other site
519441001183	Zn-dependent carboxypeptidase [Amino acid transport and metabolism]; Region: COG2317
519441001184	Peptidase family M32 includes thermostable carboxypeptidases TaqCP and PfuCP; Region: M32_Taq; cd06460
519441001185	active site
519441001186	Zn binding site [ion binding]; other site
519441001187	M18 Peptidase Aspartyl aminopeptidase; Region: M18_DAP; cd05658
519441001188	Aminopeptidase I zinc metalloprotease (M18); Region: Peptidase_M18; pfam02127
519441001189	active site
519441001190	metal binding site [ion binding]; metal-binding site
519441001191	ABC-type spermidine/putrescine transport systems, ATPase components [Amino acid transport and metabolism]; Region: PotA; COG3842
519441001192	ATP-binding cassette domain of the polyamine transporter; Region: ABC_PotA_N; cd03300
519441001193	Walker A/P-loop; other site
519441001194	ATP binding site [chemical binding]; other site
519441001195	Q-loop/lid; other site
519441001196	ABC transporter signature motif; other site
519441001197	Walker B; other site
519441001198	D-loop; other site
519441001199	H-loop/switch region; other site
519441001200	TOBE domain; Region: TOBE_2; pfam08402
519441001201	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
519441001202	putative PBP binding loops; other site
519441001203	dimer interface [polypeptide binding]; other site
519441001204	ABC-ATPase subunit interface; other site
519441001205	ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177
519441001206	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
519441001207	dimer interface [polypeptide binding]; other site
519441001208	conserved gate region; other site
519441001209	putative PBP binding loops; other site
519441001210	ABC-ATPase subunit interface; other site
519441001211	META domain; Region: META; pfam03724
519441001212	META domain; Region: META; pfam03724
519441001213	Peptidase domain in the S8 and S53 families; Region: Peptidases_S8_S53; cl10459
519441001214	catalytic residues [active]
519441001215	Autotransporter-associated beta strand repeat; Region: Autotrns_rpt; cl15373
519441001216	Tetratricopeptide repeat; Region: TPR_12; pfam13424
519441001217	Tetratricopeptide repeat; Region: TPR_12; pfam13424
519441001218	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
519441001219	binding surface
519441001220	TPR motif; other site
519441001221	Tetratricopeptide repeat; Region: TPR_12; pfam13424
519441001222	Domain of unknown function (DUF4037); Region: DUF4037; pfam13228
519441001223	Protein of unknown function (DUF4125); Region: DUF4125; pfam13526
519441001224	threonyl-tRNA synthetase; Reviewed; Region: thrS; PRK00413
519441001225	TGS _ThrRS_N:  ThrRS (threonyl-tRNA Synthetase)  is a class II tRNA synthetase that couples threonine to its cognate tRNA.  In addition to its catalytic and anticodon-binding domains, ThrRS has an N-terminal TGS domain, named after the ThrRS, GTPase, and...; Region: TGS_ThrRS_N; cd01667
519441001226	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; pfam07973
519441001227	Threonyl-tRNA synthetase (ThrRS) class II core catalytic domain. ThrRS is a homodimer. It is responsible for the attachment of threonine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ThrRS_core; cd00771
519441001228	active site
519441001229	dimer interface [polypeptide binding]; other site
519441001230	motif 1; other site
519441001231	motif 2; other site
519441001232	motif 3; other site
519441001233	ThrRS Threonyl-anticodon binding domain. ThrRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: ThrRS_anticodon; cd00860
519441001234	anticodon binding site; other site
519441001235	Bacterial BAX inhibitor (BI)-1/YccA-like proteins; Region: BI-1-like_bacterial; cd10432
519441001236	Integral membrane protein, interacts with FtsH [General function prediction only]; Region: COG0670
519441001237	Site-specific DNA methylase [DNA replication, recombination, and repair]; Region: Dam; COG0338
519441001238	D12 class N6 adenine-specific DNA methyltransferase; Region: MethyltransfD12; cl17344
519441001239	MjaII restriction endonuclease; Region: RE_MjaII; pfam09520
519441001240	Antitoxin Phd_YefM, type II toxin-antitoxin system; Region: PhdYeFM_antitox; pfam02604
519441001241	polynucleotide phosphorylase/polyadenylase; Provisional; Region: PRK11824
519441001242	Polyribonucleotide nucleotidyltransferase, repeat 1; Region: RNase_PH_PNPase_1; cd11363
519441001243	RNase E interface [polypeptide binding]; other site
519441001244	trimer interface [polypeptide binding]; other site
519441001245	Polyribonucleotide nucleotidyltransferase, RNA binding domain; Region: PNPase; pfam03726
519441001246	Polyribonucleotide nucleotidyltransferase, repeat 2; Region: RNase_PH_PNPase_2; cd11364
519441001247	RNase E interface [polypeptide binding]; other site
519441001248	trimer interface [polypeptide binding]; other site
519441001249	active site
519441001250	Polynucleotide phosphorylase (PNPase) K homology RNA-binding domain (KH). PNPase is a polyribonucleotide nucleotidyl transferase that degrades mRNA in prokaryotes and plant chloroplasts. The C-terminal region of PNPase contains domains homologous to...; Region: PNPase_KH; cd02393
519441001251	putative nucleic acid binding region [nucleotide binding]; other site
519441001252	G-X-X-G motif; other site
519441001253	S1_PNPase: Polynucleotide phosphorylase (PNPase), ), S1-like RNA-binding domain. PNPase  is a polyribonucleotide nucleotidyl transferase that degrades mRNA. It is a trimeric multidomain protein. The C-terminus contains the S1 domain which binds ssRNA; Region: S1_PNPase; cd04472
519441001254	RNA binding site [nucleotide binding]; other site
519441001255	domain interface; other site
519441001256	CDP-alcohol phosphatidyltransferase; Region: CDP-OH_P_transf; cl00453
519441001257	Cation transporter/ATPase, N-terminus; Region: Cation_ATPase_N; smart00831
519441001258	Cation transport ATPase [Inorganic ion transport and metabolism]; Region: MgtA; COG0474
519441001259	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
519441001260	Putative hydrolase of sodium-potassium ATPase alpha subunit; Region: Hydrolase_like2; pfam13246
519441001261	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
519441001262	motif II; other site
519441001263	Cation transporting ATPase, C-terminus; Region: Cation_ATPase_C; pfam00689
519441001264	D-alanyl-D-alanine carboxypeptidase; Region: Peptidase_S11; pfam00768
519441001265	Beta-lactamase enzyme family; Region: Beta-lactamase2; cl17872
519441001266	Prolipoprotein diacylglyceryl transferase; Region: LGT; pfam01790
519441001267	catalytic core domain of tryptophanyl-tRNA synthetase; Region: TrpRS_core; cd00806
519441001268	tryptophanyl-tRNA synthetase II; Reviewed; Region: PRK12282
519441001269	active site
519441001270	HIGH motif; other site
519441001271	dimer interface [polypeptide binding]; other site
519441001272	KMSKS motif; other site
519441001273	Phosphotransferase system IIA components [Carbohydrate transport and metabolism]; Region: NagE; COG2190
519441001274	HPr interaction site; other site
519441001275	glycerol kinase (GK) interaction site [polypeptide binding]; other site
519441001276	active site
519441001277	phosphorylation site [posttranslational modification]
519441001278	6-phosphofructokinase; Provisional; Region: PRK03202
519441001279	6-phosphofructokinase; Region: PFKA_ATP; TIGR02482
519441001280	active site
519441001281	ADP/pyrophosphate binding site [chemical binding]; other site
519441001282	dimerization interface [polypeptide binding]; other site
519441001283	allosteric effector site; other site
519441001284	fructose-1,6-bisphosphate binding site; other site
519441001285	pyruvate kinase; Provisional; Region: PRK09206
519441001286	Pyruvate kinase (PK):  Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low...; Region: Pyruvate_Kinase; cl17342
519441001287	domain interfaces; other site
519441001288	active site
519441001289	recombination protein RecR; Reviewed; Region: recR; PRK00076
519441001290	RecR protein; Region: RecR; pfam02132
519441001291	TOPRIM_recR: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in Escherichia coli RecR.  RecR participates in the RecFOR pathway of homologous recombinational repair in prokaryotes. This pathway provides a...; Region: TOPRIM_recR; cd01025
519441001292	putative active site [active]
519441001293	putative metal-binding site [ion binding]; other site
519441001294	tetramer interface [polypeptide binding]; other site
519441001295	S-adenosylmethionine synthetase, N-terminal domain; Region: S-AdoMet_synt_N; pfam00438
519441001296	S-adenosylmethionine synthetase; Validated; Region: PRK05250
519441001297	S-adenosylmethionine synthetase, central domain; Region: S-AdoMet_synt_M; pfam02772
519441001298	S-adenosylmethionine synthetase, C-terminal domain; Region: S-AdoMet_synt_C; pfam02773
519441001299	ABC-type oligopeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: OppA; COG4166
519441001300	The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold; Region: PBP2_OppA; cd08504
519441001301	peptide binding site [polypeptide binding]; other site
519441001302	Uncharacterized protein family (UPF0081); Region: UPF0081; pfam03652
519441001303	alanyl-tRNA synthetase; Reviewed; Region: alaS; PRK00252
519441001304	Alanyl-tRNA synthetase (AlaRS) class II core catalytic domain. AlaRS is a homodimer. It is responsible for the attachment of alanine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: AlaRS_core; cd00673
519441001305	motif 1; other site
519441001306	active site
519441001307	motif 2; other site
519441001308	motif 3; other site
519441001309	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; smart00863
519441001310	DHHA1 domain; Region: DHHA1; pfam02272
519441001311	Transcriptional regulators [Transcription]; Region: PurR; COG1609
519441001312	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
519441001313	DNA binding site [nucleotide binding]
519441001314	domain linker motif; other site
519441001315	Type 1 periplasmic binding fold superfamily; Region: Periplasmic_Binding_Protein_Type_1; cl10011
519441001316	4-alpha-glucanotransferase; Provisional; Region: PRK14508
519441001317	pullulanase, type I; Region: pulA_typeI; TIGR02104
519441001318	Early set domain associated with the catalytic domain of pullulanase (also called dextrinase and alpha-dextrin endo-1,6-alpha glucosidase); Region: E_set_Pullulanase; cd02860
519441001319	Alpha amylase catalytic domain found in Pullulanase (also called dextrinase; alpha-dextrin endo-1,6-alpha glucosidase), limit dextrinase, and related proteins; Region: AmyAc_Pullulanase_LD-like; cd11341
519441001320	Ca binding site [ion binding]; other site
519441001321	active site
519441001322	catalytic site [active]
519441001323	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
519441001324	ABC-type uncharacterized transport system, permease component [General function prediction only]; Region: COG4587
519441001325	ABC-2 family transporter protein; Region: ABC2_membrane_6; cl01496
519441001326	ABC-type uncharacterized transport system, ATPase component [General function prediction only]; Region: COG4586
519441001327	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
519441001328	Walker A/P-loop; other site
519441001329	ATP binding site [chemical binding]; other site
519441001330	Q-loop/lid; other site
519441001331	ABC transporter signature motif; other site
519441001332	Walker B; other site
519441001333	D-loop; other site
519441001334	H-loop/switch region; other site
519441001335	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
519441001336	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
519441001337	dimer interface [polypeptide binding]; other site
519441001338	conserved gate region; other site
519441001339	putative PBP binding loops; other site
519441001340	ABC-ATPase subunit interface; other site
519441001341	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
519441001342	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
519441001343	dimer interface [polypeptide binding]; other site
519441001344	conserved gate region; other site
519441001345	putative PBP binding loops; other site
519441001346	ABC-ATPase subunit interface; other site
519441001347	glycerol-3-phosphate transporter ATP-binding subunit; Provisional; Region: ugpC; PRK11650
519441001348	The N-terminal ATPase domain of the maltose transporter, MalK; Region: ABC_MalK_N; cd03301
519441001349	Walker A/P-loop; other site
519441001350	ATP binding site [chemical binding]; other site
519441001351	Q-loop/lid; other site
519441001352	ABC transporter signature motif; other site
519441001353	Walker B; other site
519441001354	D-loop; other site
519441001355	H-loop/switch region; other site
519441001356	TOBE domain; Region: TOBE_2; pfam08402
519441001357	asparaginyl-tRNA synthetase; Validated; Region: asnC; PRK03932
519441001358	EcAsnRS_like_N: N-terminal, anticodon recognition domain of the type found in Escherichia coli asparaginyl-tRNA synthetase (AsnRS) and, in Arabidopsis thaliana and Saccharomyces cerevisiae mitochondrial (mt) AsnRS. This domain is a beta-barrel domain (OB...; Region: EcAsnRS_like_N; cd04318
519441001359	putative dimer interface [polypeptide binding]; other site
519441001360	putative anticodon binding site; other site
519441001361	Asx tRNA synthetase (AspRS/AsnRS) class II core domain.  Assignment to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure and the presence of three characteristic sequence motifs in the core domain. This family includes AsnRS as well as...; Region: AsxRS_core; cd00776
519441001362	homodimer interface [polypeptide binding]; other site
519441001363	motif 1; other site
519441001364	motif 2; other site
519441001365	active site
519441001366	motif 3; other site
519441001367	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
519441001368	binding surface
519441001369	TPR motif; other site
519441001370	Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake [DNA replication, recombination, and repair / Intracellular trafficking and secretion]; Region: Smf; COG0758
519441001371	DNA topoisomerase I; Validated; Region: PRK06599
519441001372	TOPRIM_TopoIA_TopoI: The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to Escherichia coli DNA topoisomerase I.   Type IA DNA topoisomerases remove (relax) negative supercoils in the...; Region: TOPRIM_TopoIA_TopoI; cd03363
519441001373	active site
519441001374	interdomain interaction site; other site
519441001375	putative metal-binding site [ion binding]; other site
519441001376	nucleotide binding site [chemical binding]; other site
519441001377	DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cd00186
519441001378	domain I; other site
519441001379	DNA binding groove [nucleotide binding]
519441001380	phosphate binding site [ion binding]; other site
519441001381	domain II; other site
519441001382	domain III; other site
519441001383	nucleotide binding site [chemical binding]; other site
519441001384	catalytic site [active]
519441001385	domain IV; other site
519441001386	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
519441001387	Site-specific recombinase XerD [DNA replication, recombination, and repair]; Region: XerD; COG4974
519441001388	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
519441001389	active site
519441001390	DNA binding site [nucleotide binding]
519441001391	Int/Topo IB signature motif; other site
519441001392	ribosome biogenesis GTPase YqeH; Region: GTPase_YqeH; TIGR03597
519441001393	Circularly permuted YlqF-related GTPases; Region: YlqF_related_GTPase; cl17249
519441001394	GTP/Mg2+ binding site [chemical binding]; other site
519441001395	G4 box; other site
519441001396	G5 box; other site
519441001397	G1 box; other site
519441001398	Switch I region; other site
519441001399	G2 box; other site
519441001400	G3 box; other site
519441001401	Switch II region; other site
519441001402	Metal-dependent hydrolases of the beta-lactamase superfamily I [General function prediction only]; Region: PhnP; COG1235
519441001403	Predicted Zn-dependent hydrolases of the beta-lactamase fold [General function prediction only]; Region: COG2220
519441001404	Uracil-DNA glycosylases (UDG) and related enzymes; Region: UDG_like; cl00483
519441001405	ligand binding site [chemical binding]; other site
519441001406	active site
519441001407	GTP-binding protein YchF; Reviewed; Region: PRK09601
519441001408	YchF GTPase; Region: YchF; cd01900
519441001409	G1 box; other site
519441001410	GTP/Mg2+ binding site [chemical binding]; other site
519441001411	Switch I region; other site
519441001412	G2 box; other site
519441001413	Switch II region; other site
519441001414	G3 box; other site
519441001415	G4 box; other site
519441001416	G5 box; other site
519441001417	TGS_YchF_C: This subfamily represents TGS domain-containing YchF GTP-binding protein, a universally conserved GTPase whose function is unknown. The N-terminal domain of the YchF protein belongs to the Obg-like family of GTPases, and some members of the...; Region: TGS_YchF_C; cd04867
519441001418	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes [Energy production and conversion]; Region: Lpd; COG1249
519441001419	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
519441001420	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
519441001421	Mechanosensitive ion channel; Region: MS_channel; pfam00924
519441001422	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
519441001423	C-terminal processing peptidase family S41; Region: Peptidase_S41; cd06567
519441001424	Active site serine [active]
519441001425	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
519441001426	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
519441001427	non-specific DNA binding site [nucleotide binding]; other site
519441001428	salt bridge; other site
519441001429	sequence-specific DNA binding site [nucleotide binding]; other site
519441001430	Exonuclease-Endonuclease-Phosphatase (EEP) domain superfamily; Region: EEP; cl00490
519441001431	putative catalytic site [active]
519441001432	putative phosphate binding site [ion binding]; other site
519441001433	putative metal binding site [ion binding]; other site
519441001434	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
519441001435	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
519441001436	non-specific DNA binding site [nucleotide binding]; other site
519441001437	salt bridge; other site
519441001438	sequence-specific DNA binding site [nucleotide binding]; other site
519441001439	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
519441001440	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
519441001441	Walker A/P-loop; other site
519441001442	ATP binding site [chemical binding]; other site
519441001443	Q-loop/lid; other site
519441001444	ABC transporter signature motif; other site
519441001445	Walker B; other site
519441001446	D-loop; other site
519441001447	H-loop/switch region; other site
519441001448	ABC-2 family transporter protein; Region: ABC2_membrane_4; pfam12730
519441001449	ABC-2 family transporter protein; Region: ABC2_membrane_2; cl17866
519441001450	ABC-2 family transporter protein; Region: ABC2_membrane_4; pfam12730
519441001451	gliding motility-associated ABC transporter permease protein GldF; Region: ABC_perm_GldF; TIGR03518
519441001452	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
519441001453	HlyD family secretion protein; Region: HlyD_3; pfam13437
519441001454	Periplasmic binding protein; Region: Peripla_BP_6; pfam13458
519441001455	Type I periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems that are predicted to be involved in uptake of amino acids, peptides, or inorganic ions; Region: PBP1_ABC_ligand_binding_like_12; cd06347
519441001456	putative ligand binding site [chemical binding]; other site
519441001457	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
519441001458	Transmembrane subunit (TM) of Escherichia coli LivH and related proteins. LivH is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of...; Region: TM_PBP1_LivH_like; cd06582
519441001459	TM-ABC transporter signature motif; other site
519441001460	ABC-type branched-chain amino acid transport system, permease component [Amino acid transport and metabolism]; Region: LivM; COG4177
519441001461	Transmembrane subunit (TM) of Escherichia coli LivM and related proteins. LivM is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of...; Region: TM_PBP1_LivM_like; cd06581
519441001462	TM-ABC transporter signature motif; other site
519441001463	ABC-type branched-chain amino acid transport systems, ATPase component [Amino acid transport and metabolism]; Region: LivG; COG0411
519441001464	ATP-binding cassette component of branched chain amino acids transport system; Region: ABC_Mj1267_LivG_branched; cd03219
519441001465	Walker A/P-loop; other site
519441001466	ATP binding site [chemical binding]; other site
519441001467	Q-loop/lid; other site
519441001468	ABC transporter signature motif; other site
519441001469	Walker B; other site
519441001470	D-loop; other site
519441001471	H-loop/switch region; other site
519441001472	ABC-type branched-chain amino acid transport systems, ATPase component [Amino acid transport and metabolism]; Region: LivF; COG0410
519441001473	ATP-binding cassette domain of branched-chain amino acid transporter; Region: ABC_TM1139_LivF_branched; cd03224
519441001474	Walker A/P-loop; other site
519441001475	ATP binding site [chemical binding]; other site
519441001476	Q-loop/lid; other site
519441001477	ABC transporter signature motif; other site
519441001478	Walker B; other site
519441001479	D-loop; other site
519441001480	H-loop/switch region; other site
519441001481	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
519441001482	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
519441001483	CutC family; Region: CutC; cl01218
519441001484	Protein of unknown function (DUF1576); Region: DUF1576; pfam07613
519441001485	Protein of unknown function (DUF1576); Region: DUF1576; pfam07613
519441001486	Peroxiredoxin (PRX) family, Atypical 2-cys PRX subfamily; composed of PRXs containing peroxidatic and resolving cysteines, similar to the homodimeric thiol specific antioxidant (TSA) protein also known as TRX-dependent thiol peroxidase (Tpx). Tpx is a...; Region: PRX_Atyp2cys; cd03014
519441001487	dimer interface [polypeptide binding]; other site
519441001488	catalytic triad [active]
519441001489	peroxidatic and resolving cysteines [active]
519441001490	Xanthine/uracil/vitamin C permease [Nucleotide transport and    metabolism]; Region: COG2252
519441001491	Transcriptional regulator [Transcription]; Region: LysR; COG0583
519441001492	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
519441001493	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
519441001494	dimerization interface [polypeptide binding]; other site
519441001495	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism]; Region: TauC; COG0600
519441001496	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
519441001497	dimer interface [polypeptide binding]; other site
519441001498	conserved gate region; other site
519441001499	putative PBP binding loops; other site
519441001500	ABC-ATPase subunit interface; other site
519441001501	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cl17432
519441001502	NMT1/THI5 like; Region: NMT1; pfam09084
519441001503	ATP-binding cassette domain of the nitrate and sulfonate transporters; Region: ABC_NrtD_SsuB_transporters; cd03293
519441001504	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
519441001505	Walker A/P-loop; other site
519441001506	ATP binding site [chemical binding]; other site
519441001507	Q-loop/lid; other site
519441001508	ABC transporter signature motif; other site
519441001509	Walker B; other site
519441001510	D-loop; other site
519441001511	H-loop/switch region; other site
519441001512	Ribosomal protein L10 family, L10 subfamily; composed of bacterial 50S ribosomal protein and eukaryotic mitochondrial 39S ribosomal protein, L10. L10 occupies the L7/L12 stalk of the ribosome. The N-terminal domain (NTD) of L10 interacts with L11 protein...; Region: Ribosomal_L10; cd05797
519441001513	23S rRNA interface [nucleotide binding]; other site
519441001514	Interface with L7/L12 ribosomal proteins [polypeptide binding]; other site
519441001515	Ribosomal protein L7/L12. Ribosomal protein L7/L12 refers to the large ribosomal subunit proteins L7 and L12, which are identical except that L7 is acetylated at the N terminus. It is a component of the L7/L12 stalk, which is located at the surface of...; Region: Ribosomal_L7_L12; cd00387
519441001516	peripheral dimer interface [polypeptide binding]; other site
519441001517	core dimer interface [polypeptide binding]; other site
519441001518	L10 interface [polypeptide binding]; other site
519441001519	L11 interface [polypeptide binding]; other site
519441001520	putative EF-Tu interaction site [polypeptide binding]; other site
519441001521	putative EF-G interaction site [polypeptide binding]; other site
519441001522	DNA-directed RNA polymerase subunit beta; Reviewed; Region: rpoB; PRK00405
519441001523	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cl17585
519441001524	RNA polymerase Rpb2, domain 2; Region: RNA_pol_Rpb2_2; pfam04561
519441001525	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cd00653
519441001526	RPB1 interaction site [polypeptide binding]; other site
519441001527	RPB10 interaction site [polypeptide binding]; other site
519441001528	RPB11 interaction site [polypeptide binding]; other site
519441001529	RPB3 interaction site [polypeptide binding]; other site
519441001530	RPB12 interaction site [polypeptide binding]; other site
519441001531	RNA polymerase Rpb1, domain 1; Region: RNA_pol_Rpb1_1; pfam04997
519441001532	DNA-directed RNA polymerase, beta' subunit/160 kD subunit [Transcription]; Region: RpoC; COG0086
519441001533	RNA polymerase I subunit A N-terminus; Region: RPOLA_N; smart00663
519441001534	RNA polymerase Rpb1, domain 3; Region: RNA_pol_Rpb1_3; pfam04983
519441001535	RNA polymerase Rpb1, domain 4; Region: RNA_pol_Rpb1_4; pfam05000
519441001536	RNA polymerase Rpb1, domain 5; Region: RNA_pol_Rpb1_5; pfam04998
519441001537	Largest subunit of RNA polymerase (RNAP), C-terminal domain; Region: RNAP_largest_subunit_C; cl11429
519441001538	Rpb1 - Rpb6 interaction site [polypeptide binding]; other site
519441001539	Largest subunit of RNA polymerase (RNAP), C-terminal domain; Region: RNAP_largest_subunit_C; cl11429
519441001540	Apocytochrome F, C-terminal; Region: Apocytochr_F_C; cl03168
519441001541	Rpb1 - Rpb5 interaction site [polypeptide binding]; other site
519441001542	Largest subunit (beta') of Bacterial DNA-dependent RNA polymerase (RNAP), C-terminal domain; Region: RNAP_beta'_C; cd02655
519441001543	DNA binding site [nucleotide binding]
519441001544	Rpb1 (beta') - Rpb2 (beta) interaction site [polypeptide binding]; other site
519441001545	Guanylate kinase [Nucleotide transport and metabolism]; Region: Gmk; COG0194
519441001546	Guanosine monophosphate kinase (GMPK, EC 2.7.4.8), also known as guanylate kinase (GKase), catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to guanosine monophosphate (GMP) to yield adenosine diphosphate (ADP) and guanosine...; Region: GMPK; cd00071
519441001547	catalytic site [active]
519441001548	G-X2-G-X-G-K; other site
519441001549	RNA polymerase Rpb6; Region: RNA_pol_Rpb6; cl14651
519441001550	DNA primase, catalytic core; Region: dnaG; TIGR01391
519441001551	CHC2 zinc finger; Region: zf-CHC2; cl17510
519441001552	DNA primase catalytic core, N-terminal domain; Region: Toprim_N; pfam08275
519441001553	TOPRIM_DnaG_primases: The topoisomerase-primase (TORPIM) nucleotidyl transferase/hydrolase domain found in the active site regions of proteins similar to Escherichia coli DnaG. Primases synthesize RNA primers for the initiation of DNA replication. DnaG...; Region: TOPRIM_DnaG_primases; cd03364
519441001554	active site
519441001555	metal binding site [ion binding]; metal-binding site
519441001556	interdomain interaction site; other site
519441001557	RNA polymerase sigma factor RpoD; Validated; Region: PRK09210
519441001558	Sigma-70 factor, region 1.2; Region: Sigma70_r1_2; pfam00140
519441001559	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
519441001560	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
519441001561	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
519441001562	DNA binding residues [nucleotide binding]
519441001563	translation initiation factor IF-3; Reviewed; Region: infC; PRK00028
519441001564	Translation initiation factor IF-3, N-terminal domain; Region: IF3_N; pfam05198
519441001565	Translation initiation factor IF-3, C-terminal domain; Region: IF3_C; pfam00707
519441001566	Ribosomal protein L20; Region: Ribosomal_L20; cd07026
519441001567	23S rRNA binding site [nucleotide binding]; other site
519441001568	L21 binding site [polypeptide binding]; other site
519441001569	L13 binding site [polypeptide binding]; other site
519441001570	PD-(D/E)XK nuclease superfamily; Region: PDDEXK_1; pfam12705
519441001571	putative recombination protein RecB; Provisional; Region: PRK13909
519441001572	Na+/glutamate symporter [Amino acid transport and metabolism]; Region: GltS; COG0786
519441001573	50S ribosomal protein L21; Validated; Region: rplU; PRK05573
519441001574	50S ribosomal protein L21/unknown domain fusion protein; Provisional; Region: PRK12278
519441001575	Protein of unknown function (DUF464); Region: DUF464; pfam04327
519441001576	50S ribosomal protein L27; Validated; Region: rpmA; PRK05435
519441001577	Predicted EndoIII-related endonuclease [DNA replication, recombination, and repair]; Region: Nth; COG0177
519441001578	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
519441001579	minor groove reading motif; other site
519441001580	helix-hairpin-helix signature motif; other site
519441001581	substrate binding pocket [chemical binding]; other site
519441001582	active site
519441001583	iron-sulpphur binding domain in DNA-(apurinic or apyrimidinic site) lyase (subfamily of ENDO3); Region: FES; smart00525
519441001584	Beta-lactamase enzyme family; Region: Beta-lactamase2; pfam13354
519441001585	D-alanyl-D-alanine carboxypeptidase [Cell envelope biogenesis, outer membrane]; Region: DacC; COG1686
519441001586	Shikimate kinase [Amino acid transport and metabolism]; Region: AroK; COG0703
519441001587	P-loop ATPase protein family; Region: ATP_bind_2; cl15794
519441001588	excinuclease ABC subunit C; Validated; Region: uvrC; PRK00558
519441001589	Catalytic GIY-YIG domain of nucleotide excision repair endonucleases UvrC, Cho, and similar proteins; Region: GIY-YIG_UvrC_Cho; cd10434
519441001590	GIY-YIG motif/motif A; other site
519441001591	active site
519441001592	catalytic site [active]
519441001593	putative DNA binding site [nucleotide binding]; other site
519441001594	metal binding site [ion binding]; metal-binding site
519441001595	UvrC Helix-hairpin-helix N-terminal; Region: UvrC_HhH_N; pfam08459
519441001596	H3TH domains of structure-specific 5' nucleases (or flap endonuclease-1-like) involved in DNA replication, repair, and recombination; Region: H3TH_StructSpec-5'-nucleases; cl14815
519441001597	DNA binding site [nucleotide binding]
519441001598	ABC-type uncharacterized transport systems, ATPase components [General function prediction only]; Region: COG3845
519441001599	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
519441001600	Walker A/P-loop; other site
519441001601	ATP binding site [chemical binding]; other site
519441001602	Q-loop/lid; other site
519441001603	ABC transporter signature motif; other site
519441001604	Walker B; other site
519441001605	D-loop; other site
519441001606	H-loop/switch region; other site
519441001607	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
519441001608	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
519441001609	Transmembrane subunit (TM) of Treponema pallidum (Tp) RbsC-1, RbsC-2 and related proteins. This is a functionally uncharacterized subgroup of TMs which belong to a larger group of TMs of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette; Region: TM_PBP1_transp_TpRbsC_like; cd06580
519441001610	TM-ABC transporter signature motif; other site
519441001611	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
519441001612	Transmembrane subunit (TM) of Treponema pallidum (Tp) RbsC-1, RbsC-2 and related proteins. This is a functionally uncharacterized subgroup of TMs which belong to a larger group of TMs of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette; Region: TM_PBP1_transp_TpRbsC_like; cd06580
519441001613	TM-ABC transporter signature motif; other site
519441001614	Uncharacterized ABC-type transport system, periplasmic component/surface lipoprotein [General function prediction only]; Region: Med; COG1744
519441001615	Periplasmic binding domain of basic membrane lipoprotein, PnrA, in Treponema pallidum and its homologs from other bacteria and Archaea; Region: PBP1_BmpA_PnrA_like; cd06354
519441001616	ligand binding site [chemical binding]; other site
519441001617	Glycosyl transferase family, helical bundle domain; Region: Glycos_trans_3N; pfam02885
519441001618	pyrimidine-nucleoside phosphorylase; Region: Y_phosphoryl; TIGR02644
519441001619	Glycosyl transferase family, a/b domain; Region: Glycos_transf_3; pfam00591
519441001620	Pyrimidine nucleoside phosphorylase C-terminal domain; Region: PYNP_C; smart00941
519441001621	2-deoxyribose-5-phosphate aldolase (DERA) of the DeoC family; Region: DeoC; cd00959
519441001622	intersubunit interface [polypeptide binding]; other site
519441001623	active site
519441001624	catalytic residue [active]
519441001625	purine nucleoside phosphorylase; Reviewed; Region: deoD; PRK05819
519441001626	Cytidine deaminase zinc-binding domain. These enzymes are Zn dependent. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a water molecule to form a hydroxide ion that performs a nucleophilic attack on...; Region: cytidine_deaminase; cd01283
519441001627	active site
519441001628	catalytic motif [active]
519441001629	Zn binding site [ion binding]; other site
519441001630	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
519441001631	active site
519441001632	Dimethyladenosine transferase (rRNA methylation) [Translation, ribosomal structure and biogenesis]; Region: KsgA; COG0030
519441001633	16S ribosomal RNA methyltransferase KsgA/Dim1 family protein; Reviewed; Region: ksgA; PRK00274
519441001634	Xaa-His dipeptidase; Region: aa-his-dipept; TIGR01893
519441001635	M20 Peptidase D has specificity for beta-alanyl-L-histidine dipeptide; Region: M20_pepD; cd03890
519441001636	metal binding site [ion binding]; metal-binding site
519441001637	dimer interface [polypeptide binding]; other site
519441001638	Topoisomerase-primase domain. This is a nucleotidyl transferase/hydrolase domain found in type IA, type IIA and type IIB topoisomerases, bacterial DnaG-type primases, small primase-like proteins from bacteria and archaea, OLD family nucleases from...; Region: TOPRIM; cl00718
519441001639	ribonuclease M5; Region: 5S_RNA_mat_M5; TIGR00334
519441001640	active site
519441001641	metal binding site [ion binding]; metal-binding site
519441001642	Domain of unknown function (DUF4093); Region: DUF4093; pfam13331
519441001643	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
519441001644	Cytidylyltransferase; Region: CTP_transf_2; pfam01467
519441001645	active site
519441001646	nucleotide binding site [chemical binding]; other site
519441001647	HIGH motif; other site
519441001648	KMSKS motif; other site
519441001649	50S ribosomal protein L33; Validated; Region: rpmG; PRK00595
519441001650	transcription antitermination protein NusG; Validated; Region: nusG; PRK05609
519441001651	Bacterial N-Utilization Substance G (NusG) N-terminal (NGN) domain, subgroup 1; Region: NGN_Bact_1; cd09891
519441001652	putative homodimer interface [polypeptide binding]; other site
519441001653	NusG contains an NGN domain at its N-terminus and KOW motif at its C-terminus; Region: KOW_NusG; cd06091
519441001654	heterodimer interface [polypeptide binding]; other site
519441001655	homodimer interface [polypeptide binding]; other site
519441001656	50S ribosomal protein L11; Validated; Region: rplK; PRK00140
519441001657	Ribosomal protein L11. Ribosomal protein L11, together with proteins L10 and L7/L12, and 23S rRNA, form the L7/L12 stalk on the surface of the large subunit of the ribosome. The homologous eukaryotic cytoplasmic protein is also called 60S ribosomal...; Region: Ribosomal_L11; cd00349
519441001658	23S rRNA interface [nucleotide binding]; other site
519441001659	L7/L12 interface [polypeptide binding]; other site
519441001660	putative thiostrepton binding site; other site
519441001661	L25 interface [polypeptide binding]; other site
519441001662	Ribosomal protein L1.  The L1 protein, located near the E-site of the ribosome, forms part of the L1 stalk along with 23S rRNA.  In bacteria and archaea, L1 functions both as a ribosomal protein that binds rRNA, and as a translation repressor that binds...; Region: Ribosomal_L1; cd00403
519441001663	mRNA/rRNA interface [nucleotide binding]; other site
519441001664	Transposase zinc-binding domain; Region: Zn_Tnp_IS91; pfam14319
519441001665	Putative transposase; Region: Y2_Tnp; pfam04986
519441001666	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
519441001667	active site
519441001668	50S ribosomal protein L31 type B; Reviewed; Region: rpmE2; PRK01678
519441001669	30S ribosomal protein S20; Reviewed; Region: rpsT; PRK00239
519441001670	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cl17251
519441001671	Rad3-related DNA helicases [Transcription / DNA replication, recombination, and repair]; Region: DinG; COG1199
519441001672	DEAD/DEAH box helicase; Region: DEAD; pfam00270
519441001673	ATP binding site [chemical binding]; other site
519441001674	DEAD_2; Region: DEAD_2; pfam06733
519441001675	Helicase C-terminal domain; Region: Helicase_C_2; pfam13307
519441001676	Predicted membrane-associated HD superfamily hydrolase [General function prediction only]; Region: COG1480
519441001677	7TM receptor with intracellular HD hydrolase; Region: 7TM-7TMR_HD; pfam07698
519441001678	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
519441001679	Zn2+ binding site [ion binding]; other site
519441001680	Mg2+ binding site [ion binding]; other site
519441001681	metal-binding heat shock protein; Provisional; Region: PRK00016
519441001682	Prokaryotic diacylglycerol kinase; Region: DAGK_prokar; pfam01219
519441001683	PAP2_like proteins, diacylglycerol_kinase like sub-family. In some prokaryotes, PAP2_like phosphatase domains appear fused to E. coli DAGK-like trans-membrane diacylglycerol kinase domains. The cellular function of these architectures remains to be...; Region: PAP2_diacylglycerolkinase; cd03383
519441001684	active site
519441001685	putative manganese-dependent inorganic pyrophosphatase; Provisional; Region: PRK05427
519441001686	The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called...; Region: CBS_pair; cl15354
519441001687	DHHA2 domain; Region: DHHA2; pfam02833
519441001688	Ribosomal protein S15 (prokaryotic)_S13 (eukaryotic) binds the central domain of 16S rRNA and is required for assembly of the small ribosomal subunit and for intersubunit association, thus representing a key element in the assembly of the whole ribosome; Region: Ribosomal_S15p_S13e; cd00353
519441001689	16S/18S rRNA binding site [nucleotide binding]; other site
519441001690	S13e-L30e interaction site [polypeptide binding]; other site
519441001691	25S rRNA binding site [nucleotide binding]; other site
519441001692	Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; Region: MATE_like_1; cd13140
519441001693	Na+-driven multidrug efflux pump [Defense mechanisms]; Region: NorM; COG0534
519441001694	Transposase zinc-binding domain; Region: Zn_Tnp_IS91; pfam14319
519441001695	Putative transposase; Region: Y2_Tnp; pfam04986
519441001696	NAD pyrophosphatase/5'-nucleotidase NadN; Region: nadN; TIGR01530
519441001697	CD73 ecto-5'-nucleotidase and related proteins, N-terminal metallophosphatase domain; Region: MPP_CD73_N; cd07409
519441001698	active site
519441001699	metal binding site [ion binding]; metal-binding site
519441001700	5'-nucleotidase, C-terminal domain; Region: 5_nucleotid_C; pfam02872
519441001701	NrdI Flavodoxin like; Region: Flavodoxin_NdrI; pfam07972
519441001702	ribonucleotide-diphosphate reductase subunit alpha; Validated; Region: PRK07632
519441001703	Ribonucleotide reductase N-terminal; Region: RNR_N; pfam08343
519441001704	Class I ribonucleotide reductase; Region: RNR_I; cd01679
519441001705	active site
519441001706	dimer interface [polypeptide binding]; other site
519441001707	catalytic residues [active]
519441001708	effector binding site; other site
519441001709	R2 peptide binding site; other site
519441001710	ribonucleotide-diphosphate reductase subunit beta; Provisional; Region: nrdF2; PRK13966
519441001711	Ribonucleotide Reductase, R2/beta subunit, ferritin-like diiron-binding domain; Region: RNRR2; cd01049
519441001712	dimer interface [polypeptide binding]; other site
519441001713	putative radical transfer pathway; other site
519441001714	diiron center [ion binding]; other site
519441001715	tyrosyl radical; other site
519441001716	Major Facilitator Superfamily; Region: MFS_1; pfam07690
519441001717	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
519441001718	putative substrate translocation pore; other site
519441001719	Hypothetical protein (DUF2513); Region: DUF2513; pfam10711
519441001720	Protein of unknown function (DUF1361); Region: DUF1361; cl01784
519441001721	Nucleoside 2-deoxyribosyltransferase; Region: Nuc_deoxyrib_tr; pfam05014
519441001722	Protein of unknown function (DUF1275); Region: DUF1275; pfam06912
519441001723	aspartate aminotransferase; Provisional; Region: PRK07568
519441001724	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
519441001725	pyridoxal 5'-phosphate binding site [chemical binding]; other site
519441001726	homodimer interface [polypeptide binding]; other site
519441001727	catalytic residue [active]
519441001728	Pseudouridylate synthase [Translation, ribosomal structure and biogenesis]; Region: TruA; COG0101
519441001729	Pseudouridine synthases catalyze the isomerization of specific uridines in an RNA molecule to pseudouridines (5-ribosyluracil, psi); Region: PseudoU_synth; cl00130
519441001730	active site
519441001731	Protein of unknown function (DUF997); Region: DUF997; pfam06196
519441001732	Predicted symporter [General function prediction only]; Region: DhlC; COG4147
519441001733	Na(+)/pantothenate cotransporters: PanF of Escherichia coli and related proteins; solute binding domain; Region: SLC5sbd_PanF; cd10327
519441001734	Na binding site [ion binding]; other site
519441001735	Indigoidine synthase A like protein; Region: Indigoidine_A; pfam04227
519441001736	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
519441001737	YeiC-like sugar kinase.  Found in eukaryotes and bacteria, YeiC-like kinase is part of the ribokinase/pfkB sugar kinase superfamily. Its oligomerization state is unknown at this time; Region: YeiC_kinase_like; cd01941
519441001738	substrate binding site [chemical binding]; other site
519441001739	ATP binding site [chemical binding]; other site
519441001740	Transposase zinc-binding domain; Region: Zn_Tnp_IS91; pfam14319
519441001741	Putative transposase; Region: Y2_Tnp; pfam04986
519441001742	Ribose/Galactose Isomerase; Region: LacAB_rpiB; pfam02502
519441001743	Protein Kinase C Interacting protein related (PKCI): PKCI and related proteins belong to the ubiquitous HIT family of hydrolases that act on alpha-phosphates of ribonucleotides. The members of this subgroup have a conserved HxHxHxx motif (x is a...; Region: PKCI_related; cd01276
519441001744	nucleotide binding site/active site [active]
519441001745	HIT family signature motif; other site
519441001746	catalytic residue [active]
519441001747	rRNA methylases [Translation, ribosomal structure and biogenesis]; Region: SpoU; COG0566
519441001748	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
519441001749	ethanol-active dehydrogenase/acetaldehyde-active reductase; Provisional; Region: PRK09422
519441001750	Cinnamyl alcohol dehydrogenases (CAD); Region: CAD3; cd08297
519441001751	NAD binding site [chemical binding]; other site
519441001752	substrate binding site [chemical binding]; other site
519441001753	catalytic Zn binding site [ion binding]; other site
519441001754	tetramer interface [polypeptide binding]; other site
519441001755	structural Zn binding site [ion binding]; other site
519441001756	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
519441001757	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
519441001758	Walker A/P-loop; other site
519441001759	ATP binding site [chemical binding]; other site
519441001760	Q-loop/lid; other site
519441001761	ABC transporter signature motif; other site
519441001762	Walker B; other site
519441001763	D-loop; other site
519441001764	H-loop/switch region; other site
519441001765	Patatin-like phospholipase; includes PNPLA8, PNPLA9, and Pat17; Region: Pat17_PNPLA8_PNPLA9_like; cd07199
519441001766	active site
519441001767	nucleophile elbow; other site
519441001768	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cl02542
519441001769	HSP70 interaction site [polypeptide binding]; other site
519441001770	TatD like proteins;  E.coli TatD is a cytoplasmic protein, shown to have magnesium dependent DNase activity; Region: TatD_DNAse; cd01310
519441001771	active site
519441001772	4'-phosphopantetheinyl transferase; Provisional; Region: acpS; PRK00070
519441001773	helix_turn_helix isocitrate lyase regulation; Region: HTH_ICLR; smart00346
519441001774	Transcriptional regulator [Transcription]; Region: IclR; COG1414
519441001775	Bacterial transcriptional regulator; Region: IclR; pfam01614
519441001776	Metal-dependent amidase/aminoacylase/carboxypeptidase [General function prediction only]; Region: AbgB; COG1473
519441001777	M20 Peptidase Aminoacylase 1 family; Region: M20_Acy1; cd03886
519441001778	metal binding site [ion binding]; metal-binding site
519441001779	dimer interface [polypeptide binding]; other site
519441001780	SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase [Translation, ribosomal structure and biogenesis]; Region: TrmA; COG2265
519441001781	TRAM domain; Region: TRAM; cl01282
519441001782	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
519441001783	S-adenosylmethionine binding site [chemical binding]; other site
519441001784	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
519441001785	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
519441001786	Walker A/P-loop; other site
519441001787	ATP binding site [chemical binding]; other site
519441001788	Q-loop/lid; other site
519441001789	ABC transporter signature motif; other site
519441001790	Walker B; other site
519441001791	D-loop; other site
519441001792	H-loop/switch region; other site
519441001793	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
519441001794	dimer interface [polypeptide binding]; other site
519441001795	conserved gate region; other site
519441001796	ABC-ATPase subunit interface; other site
519441001797	ABC-type proline/glycine betaine transport systems, periplasmic components [Amino acid transport and metabolism]; Region: ProX; cl17891
519441001798	Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein) [Cell envelope biogenesis, outer membrane]; Region: OpuBC; COG1732
519441001799	putative glycerol-3-phosphate acyltransferase PlsY; Provisional; Region: PRK00220
519441001800	NAD(P)H-dependent glycerol-3-phosphate dehydrogenase; Validated; Region: gpsA; PRK00094
519441001801	NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; Region: NAD_Gly3P_dh_N; pfam01210
519441001802	NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus; Region: NAD_Gly3P_dh_C; pfam07479
519441001803	RNA polymerase sigma factor RpoD, C-terminal domain; Region: RpoD_Cterm; TIGR02393
519441001804	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
519441001805	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
519441001806	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
519441001807	DNA binding residues [nucleotide binding]
519441001808	Beta clamp domain.  The beta subunit (processivity factor) of DNA polymerase III holoenzyme, refered to as the beta clamp, forms a ring shaped dimer that encircles dsDNA (sliding clamp) in bacteria.  The beta-clamp is structurally similar to the trimeric...; Region: beta_clamp; cd00140
519441001809	DNA polymerase III subunit beta; Validated; Region: PRK05643
519441001810	putative DNA binding surface [nucleotide binding]; other site
519441001811	dimer interface [polypeptide binding]; other site
519441001812	beta-clamp/clamp loader binding surface; other site
519441001813	beta-clamp/translesion DNA polymerase binding surface; other site
519441001814	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
519441001815	haloacid dehalogenase-like hydrolase; Region: Hydrolase; pfam00702
519441001816	hybrid cluster protein-associated redox disulfide domain; Region: prismane_assoc; TIGR03980
519441001817	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
519441001818	non-specific DNA binding site [nucleotide binding]; other site
519441001819	salt bridge; other site
519441001820	sequence-specific DNA binding site [nucleotide binding]; other site
519441001821	phosphoglucosamine mutase; Provisional; Region: glmM; PRK14316
519441001822	GlmM is a bacterial phosphoglucosamine mutase (PNGM) that belongs to the alpha-D-phosphohexomutase superfamily. It is required for the interconversion of glucosamine-6-phosphate and glucosamine-1-phosphate in the biosynthetic pathway of...; Region: GlmM; cd05802
519441001823	active site
519441001824	substrate binding site [chemical binding]; other site
519441001825	metal binding site [ion binding]; metal-binding site
519441001826	Methyltransferase domain; Region: Methyltransf_31; pfam13847
519441001827	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
519441001828	S-adenosylmethionine binding site [chemical binding]; other site
519441001829	Trimeric dUTP diphosphatases; Region: trimeric_dUTPase; cd07557
519441001830	trimer interface [polypeptide binding]; other site
519441001831	active site
519441001832	Predicted O-methyltransferase [General function prediction only]; Region: COG4123
519441001833	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
519441001834	S-adenosylmethionine binding site [chemical binding]; other site
519441001835	Cis (Z)-Isoprenyl Diphosphate Synthases (cis-IPPS); homodimers which catalyze the successive 1'-4 condensation of the isopentenyl diphosphate (IPP) molecule to trans,trans-farnesyl diphosphate (FPP) or to cis,trans-FPP to form long-chain polyprenyl...; Region: CIS_IPPS; cl00230
519441001836	Putative undecaprenyl diphosphate synthase; Region: Prenyltransf; pfam01255
519441001837	catalytic residue [active]
519441001838	putative FPP diphosphate  binding site; other site
519441001839	putative FPP binding hydrophobic cleft; other site
519441001840	dimer interface [polypeptide binding]; other site
519441001841	putative IPP diphosphate binding site; other site
519441001842	CDP-diglyceride synthetase [Lipid metabolism]; Region: CdsA; COG0575
519441001843	Cytidylyltransferase family; Region: CTP_transf_1; pfam01148
519441001844	ribonuclease PH; Reviewed; Region: rph; PRK00173
519441001845	Ribonuclease PH; Region: RNase_PH_bact; cd11362
519441001846	hexamer interface [polypeptide binding]; other site
519441001847	active site
519441001848	Predicted Fe-S-cluster redox enzyme [General function prediction only]; Region: COG0820
519441001849	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
519441001850	FeS/SAM binding site; other site
519441001851	Transglycosylase; Region: Transgly; pfam00912
519441001852	penicillin-binding protein, 1A family; Region: PBP_1a_fam; TIGR02074
519441001853	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
519441001854	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
519441001855	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
519441001856	substrate binding pocket [chemical binding]; other site
519441001857	membrane-bound complex binding site; other site
519441001858	hinge residues; other site
519441001859	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
519441001860	dimer interface [polypeptide binding]; other site
519441001861	conserved gate region; other site
519441001862	putative PBP binding loops; other site
519441001863	ABC-ATPase subunit interface; other site
519441001864	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
519441001865	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
519441001866	Walker A/P-loop; other site
519441001867	ATP binding site [chemical binding]; other site
519441001868	Q-loop/lid; other site
519441001869	ABC transporter signature motif; other site
519441001870	Walker B; other site
519441001871	D-loop; other site
519441001872	H-loop/switch region; other site
519441001873	YadA-like, left-handed beta-roll; Region: LbR_YadA-like; cd12820
519441001874	trimer interface [polypeptide binding]; other site
519441001875	YadA-like C-terminal region; Region: YadA; pfam03895
519441001876	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
519441001877	ligand binding site [chemical binding]; other site
519441001878	Putative methyltransferase; Region: Methyltransf_4; cl17290
519441001879	Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins...; Region: FHA; cl00062
519441001880	phosphopeptide binding site; other site
519441001881	Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins...; Region: FHA; cd00060
519441001882	phosphopeptide binding site; other site
519441001883	Lipoproteins [Cell envelope biogenesis, outer membrane]; Region: RlpA; COG0797
519441001884	Rare lipoprotein A (RlpA)-like double-psi beta-barrel; Region: DPBB_1; pfam03330
519441001885	amidase; Provisional; Region: PRK06529
519441001886	Amidase; Region: Amidase; cl11426
519441001887	Dipeptidyl aminopeptidases/acylaminoacyl-peptidases [Amino acid transport and metabolism]; Region: DAP2; COG1506
519441001888	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
519441001889	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
519441001890	active site
519441001891	phosphorylation site [posttranslational modification]
519441001892	peptide chain release factor 1; Validated; Region: prfA; PRK00591
519441001893	This domain is found in peptide chain release factors; Region: PCRF; smart00937
519441001894	RF-1 domain; Region: RF-1; pfam00472
519441001895	N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase; Provisional; Region: PRK09328
519441001896	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
519441001897	S-adenosylmethionine binding site [chemical binding]; other site
519441001898	S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Provisional; Region: queA; PRK00147
519441001899	S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Region: queA; TIGR00113
519441001900	N6-adenine-specific methylase [DNA replication, recombination, and repair]; Region: COG0742
519441001901	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
519441001902	S-adenosylmethionine binding site [chemical binding]; other site
519441001903	Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; Region: IspA; COG0142
519441001904	Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685
519441001905	substrate binding pocket [chemical binding]; other site
519441001906	chain length determination region; other site
519441001907	substrate-Mg2+ binding site; other site
519441001908	catalytic residues [active]
519441001909	aspartate-rich region 1; other site
519441001910	active site lid residues [active]
519441001911	aspartate-rich region 2; other site
519441001912	Multi-copper polyphenol oxidoreductase laccase; Region: Cu-oxidase_4; pfam02578
519441001913	preprotein translocase subunit SecA; Reviewed; Region: PRK12904
519441001914	SecA preprotein cross-linking domain; Region: SecA_PP_bind; smart00958
519441001915	DL-methionine transporter ATP-binding subunit; Provisional; Region: metN; PRK11153
519441001916	ATP-binding cassette domain of methionine transporter; Region: ABC_MetN_methionine_transporter; cd03258
519441001917	Walker A/P-loop; other site
519441001918	ATP binding site [chemical binding]; other site
519441001919	Q-loop/lid; other site
519441001920	ABC transporter signature motif; other site
519441001921	Walker B; other site
519441001922	D-loop; other site
519441001923	H-loop/switch region; other site
519441001924	This domain is found at the C-terminus of ABC transporter proteins involved in D-methionine transport as well as a number of ferredoxin-like proteins; Region: NIL; smart00930
519441001925	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
519441001926	ABC-ATPase subunit interface; other site
519441001927	ABC-type metal ion transport system, periplasmic component/surface antigen [Inorganic ion transport and metabolism]; Region: NlpA; COG1464
519441001928	NLPA lipoprotein; Region: Lipoprotein_9; pfam03180
519441001929	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; cl00465
519441001930	YceG-like family; Region: YceG; pfam02618
519441001931	proteins similar to Escherichia coli yceG; Region: yceG_like; cl17666
519441001932	dimerization interface [polypeptide binding]; other site
519441001933	Stage II sporulation protein; Region: SpoIID; pfam08486
519441001934	SpoIID/LytB domain; Region: SpoIID_LytB; TIGR02669
519441001935	tRNA(Ile)-lysidine synthase MesJ [Cell cycle control, cell division, chromosome partitioning]; Region: MesJ; COG0037
519441001936	N-terminal domain of predicted ATPase of the PP-loop faimly implicated in cell cycle control [Cell division and chromosome partitioning]. This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases...; Region: PP-ATPase; cd01992
519441001937	Ligand Binding Site [chemical binding]; other site
519441001938	TilS substrate C-terminal domain; Region: TilS_C; smart00977
519441001939	FtsH Extracellular; Region: FtsH_ext; pfam06480
519441001940	ATP-dependent metalloprotease FtsH; Region: FtsH_fam; TIGR01241
519441001941	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
519441001942	Walker A motif; other site
519441001943	ATP binding site [chemical binding]; other site
519441001944	Walker B motif; other site
519441001945	arginine finger; other site
519441001946	Peptidase family M41; Region: Peptidase_M41; pfam01434
519441001947	Ribosomal protein L32 [Translation, ribosomal structure and biogenesis]; Region: RpmF; COG0333
519441001948	recombination and DNA strand exchange inhibitor protein; Reviewed; Region: PRK00409
519441001949	MutS domain III; Region: MutS_III; pfam05192
519441001950	ATP-binding cassette domain of MutS2; Region: ABC_MutS2; cd03280
519441001951	Walker A/P-loop; other site
519441001952	ATP binding site [chemical binding]; other site
519441001953	Q-loop/lid; other site
519441001954	ABC transporter signature motif; other site
519441001955	Walker B; other site
519441001956	D-loop; other site
519441001957	H-loop/switch region; other site
519441001958	Smr domain; Region: Smr; pfam01713
519441001959	cysteinyl-tRNA synthetase; Validated; Region: cysS; PRK00260
519441001960	catalytic core domain of cysteinyl tRNA synthetase; Region: CysRS_core; cd00672
519441001961	active site
519441001962	HIGH motif; other site
519441001963	catalytic core domain of cysteinyl tRNA synthetase; Region: CysRS_core; cd00672
519441001964	KMSKS motif; other site
519441001965	Anticodon-binding domain of class Ia aminoacyl tRNA synthetases and similar domains; Region: Anticodon_Ia_like; cl12020
519441001966	rod shape-determining protein MreB; Provisional; Region: PRK13930
519441001967	MreB and similar proteins; Region: MreB_like; cd10225
519441001968	nucleotide binding site [chemical binding]; other site
519441001969	Mg binding site [ion binding]; other site
519441001970	putative protofilament interaction site [polypeptide binding]; other site
519441001971	RodZ interaction site [polypeptide binding]; other site
519441001972	DNA polymerase III, delta subunit; Region: DNA_pol3_delta2; pfam13177
519441001973	glutamate racemase; Provisional; Region: PRK00865
519441001974	Holliday junction DNA helicase RuvA; Reviewed; Region: ruvA; PRK00116
519441001975	RuvA N terminal domain; Region: RuvA_N; pfam01330
519441001976	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cl14786
519441001977	excinuclease ABC subunit A; Reviewed; Region: uvrA; PRK00349
519441001978	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
519441001979	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
519441001980	ATP-binding cassette domain II of the excision repair protein UvrA; Region: ABC_UvrA_II; cd03271
519441001981	aminotransferase A; Validated; Region: PRK07683
519441001982	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
519441001983	pyridoxal 5'-phosphate binding site [chemical binding]; other site
519441001984	homodimer interface [polypeptide binding]; other site
519441001985	catalytic residue [active]
519441001986	SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase [Translation, ribosomal structure and biogenesis]; Region: TrmA; COG2265
519441001987	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
519441001988	S-adenosylmethionine binding site [chemical binding]; other site
519441001989	Replication initiator protein A (RepA) N-terminus; Region: RepA_N; pfam06970
519441001990	Domain of unknown function (DUF4366); Region: DUF4366; pfam14283
519441001991	KilA-N domain; Region: KilA-N; pfam04383
519441001992	Retron-type reverse transcriptase [DNA replication, recombination, and repair]; Region: COG3344
519441001993	N-terminal domain of reverse transcriptase; Region: RVT_N; pfam13655
519441001994	RT_G2_intron: Reverse transcriptases (RTs) with group II intron origin. RT transcribes DNA using RNA as template. Proteins in this subfamily are found in bacterial and mitochondrial group II introns. Their most probable ancestor was a retrotransposable...; Region: RT_G2_intron; cd01651
519441001995	putative active site [active]
519441001996	putative NTP binding site [chemical binding]; other site
519441001997	putative nucleic acid binding site [nucleotide binding]; other site
519441001998	Group II intron, maturase-specific domain; Region: GIIM; pfam08388
519441001999	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
519441002000	non-specific DNA binding site [nucleotide binding]; other site
519441002001	salt bridge; other site
519441002002	sequence-specific DNA binding site [nucleotide binding]; other site
519441002003	Type I restriction-modification system methyltransferase subunit [Defense mechanisms]; Region: HsdM; COG0286
519441002004	HsdM N-terminal domain; Region: HsdM_N; pfam12161
519441002005	Methyltransferase domain; Region: Methyltransf_26; pfam13659
519441002006	Restriction endonuclease S subunits [Defense mechanisms]; Region: HsdS; COG0732
519441002007	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
519441002008	Type I site-specific restriction-modification system, R (restriction) subunit and related helicases [Defense mechanisms]; Region: COG0610
519441002009	Type I restriction enzyme R protein N terminus (HSDR_N); Region: HSDR_N; pfam04313
519441002010	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
519441002011	ATP binding site [chemical binding]; other site
519441002012	putative Mg++ binding site [ion binding]; other site
519441002013	Domain of unknown function (DUF1837); Region: DUF1837; pfam08878
519441002014	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
519441002015	ATP binding site [chemical binding]; other site
519441002016	putative Mg++ binding site [ion binding]; other site
519441002017	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
519441002018	nucleotide binding region [chemical binding]; other site
519441002019	ATP-binding site [chemical binding]; other site
519441002020	Relaxase/Mobilisation nuclease domain; Region: Relaxase; pfam03432
519441002021	RT_G2_intron: Reverse transcriptases (RTs) with group II intron origin. RT transcribes DNA using RNA as template. Proteins in this subfamily are found in bacterial and mitochondrial group II introns. Their most probable ancestor was a retrotransposable...; Region: RT_G2_intron; cd01651
519441002022	Reverse transcriptase (RNA-dependent DNA polymerase); Region: RVT_1; pfam00078
519441002023	putative active site [active]
519441002024	putative NTP binding site [chemical binding]; other site
519441002025	putative nucleic acid binding site [nucleotide binding]; other site
519441002026	Reverse transcriptase (RNA-dependent DNA polymerase); Region: RVT_1; pfam00078
519441002027	Type II intron maturase; Region: Intron_maturas2; pfam01348
519441002028	Relaxase/Mobilisation nuclease domain; Region: Relaxase; pfam03432
519441002029	Transcriptional regulators [Transcription]; Region: PurR; COG1609
519441002030	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
519441002031	DNA binding site [nucleotide binding]
519441002032	domain linker motif; other site
519441002033	Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267
519441002034	dimerization interface [polypeptide binding]; other site
519441002035	ligand binding site [chemical binding]; other site
519441002036	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
519441002037	Coenzyme A binding pocket [chemical binding]; other site
519441002038	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
519441002039	Ribokinase catalyses the phosphorylation of ribose to ribose-5-phosphate using ATP. This reaction is the first step in the ribose metabolism. It traps ribose within the cell after uptake and also prepares the sugar for use in the synthesis of nucleotides...; Region: ribokinase; cd01174
519441002040	substrate binding site [chemical binding]; other site
519441002041	dimer interface [polypeptide binding]; other site
519441002042	ATP binding site [chemical binding]; other site
519441002043	nuc_hydro_IU_UC_XIUA: inosine-uridine preferring, xanthosine-inosine-uridine-adenosine-preferring and, uridine-cytidine preferring nucleoside hydrolases. Nucleoside hydrolases cleave the N-glycosidic bond in nucleosides generating ribose and the...; Region: nuc_hydro_IU_UC_XIUA; cd02651
519441002044	active site
519441002045	tetramer interface [polypeptide binding]; other site
519441002046	C4-dicarboxylate transporter [Energy production and conversion]; Region: DcuC; COG3069
519441002047	C4-dicarboxylate anaerobic carrier; Region: DcuC; pfam03606
519441002048	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
519441002049	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
519441002050	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
519441002051	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
519441002052	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
519441002053	Walker A/P-loop; other site
519441002054	ATP binding site [chemical binding]; other site
519441002055	Q-loop/lid; other site
519441002056	ABC transporter signature motif; other site
519441002057	Walker B; other site
519441002058	D-loop; other site
519441002059	H-loop/switch region; other site
519441002060	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
519441002061	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
519441002062	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
519441002063	Walker A/P-loop; other site
519441002064	ATP binding site [chemical binding]; other site
519441002065	Q-loop/lid; other site
519441002066	ABC transporter signature motif; other site
519441002067	Walker B; other site
519441002068	D-loop; other site
519441002069	H-loop/switch region; other site
519441002070	Hypothetical bacterial integral membrane protein (Trep_Strep); Region: Trep_Strep; pfam09605
519441002071	Cobalt transport protein; Region: CbiQ; cl00463
519441002072	ATPase components of various ABC-type transport systems, contain duplicated ATPase [General function prediction only]; Region: COG1123
519441002073	First domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain1; cd03225
519441002074	Walker A/P-loop; other site
519441002075	ATP binding site [chemical binding]; other site
519441002076	Q-loop/lid; other site
519441002077	ABC transporter signature motif; other site
519441002078	Walker B; other site
519441002079	D-loop; other site
519441002080	H-loop/switch region; other site
519441002081	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
519441002082	Walker A/P-loop; other site
519441002083	ATP binding site [chemical binding]; other site
519441002084	Q-loop/lid; other site
519441002085	ABC transporter signature motif; other site
519441002086	Walker B; other site
519441002087	D-loop; other site
519441002088	H-loop/switch region; other site
519441002089	putative nicotinate phosphoribosyltransferase; Provisional; Region: PRK09198
519441002090	pre-B-cell colony-enhancing factor (PBEF)-like. The mammalian members of this group of nicotinate phosphoribosyltransferases (NAPRTases) were originally identified as genes whose expression is upregulated upon activation in lymphoid cells. In general; Region: PBEF_like; cd01569
519441002091	active site
519441002092	Chloride channel protein EriC [Inorganic ion transport and metabolism]; Region: EriC; COG0038
519441002093	ClC chloride channel EriC.  This domain is found in the EriC chloride transporters that mediate the extreme acid resistance response in eubacteria and archaea. This response allows bacteria to survive in the acidic environments by decarboxylation-linked...; Region: EriC; cd01031
519441002094	Cl- selectivity filter; other site
519441002095	Cl- binding residues [ion binding]; other site
519441002096	pore gating glutamate residue; other site
519441002097	dimer interface [polypeptide binding]; other site
519441002098	H+/Cl- coupling transport residue; other site
519441002099	TrkA-C domain; Region: TrkA_C; pfam02080
519441002100	Putative small multi-drug export protein; Region: Sm_multidrug_ex; pfam06695
519441002101	Phage late control gene D protein (GPD); Region: Phage_GPD; pfam05954
519441002102	Domain of unknown function (DUF4280); Region: DUF4280; pfam14107
519441002103	TIGR02594 family protein; Region: TIGR02594
519441002104	Predicted membrane GTPase involved in stress response [Signal transduction mechanisms]; Region: TypA; COG1217
519441002105	Tyrosine phosphorylated protein A (TypA)/BipA family belongs to ribosome-binding GTPases; Region: TypA_BipA; cd01891
519441002106	G1 box; other site
519441002107	putative GEF interaction site [polypeptide binding]; other site
519441002108	GTP/Mg2+ binding site [chemical binding]; other site
519441002109	Switch I region; other site
519441002110	G2 box; other site
519441002111	G3 box; other site
519441002112	Switch II region; other site
519441002113	G4 box; other site
519441002114	G5 box; other site
519441002115	BipA_TypA_II: domain II of BipA (also called TypA) having homology to domain II of the elongation factors (EFs) EF-G and EF-Tu.  BipA is a highly conserved protein with global regulatory properties in Escherichia coli. BipA is phosphorylated on a...; Region: BipA_TypA_II; cd03691
519441002116	BipA_TypA_C: a C-terminal portion of BipA or TypA having homology to the C terminal domains of the elongation factors EF-G and EF-2. A member of the ribosome binding GTPase superfamily, BipA is widely distributed in bacteria and plants.  BipA is a highly...; Region: BipA_TypA_C; cd03710
519441002117	SdpI/YhfL protein family; Region: SdpI; pfam13630
519441002118	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
519441002119	HlyD family secretion protein; Region: HlyD_3; pfam13437
519441002120	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
519441002121	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
519441002122	Walker A/P-loop; other site
519441002123	ATP binding site [chemical binding]; other site
519441002124	Q-loop/lid; other site
519441002125	ABC transporter signature motif; other site
519441002126	Walker B; other site
519441002127	D-loop; other site
519441002128	H-loop/switch region; other site
519441002129	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
519441002130	FtsX-like permease family; Region: FtsX; pfam02687
519441002131	Cation efflux family; Region: Cation_efflux; pfam01545
519441002132	Predicted Co/Zn/Cd cation transporters [Inorganic ion transport and metabolism]; Region: MMT1; COG0053
519441002133	Collagenase and related proteases [Posttranslational modification, protein turnover, chaperones]; Region: COG0826
519441002134	DRE-TIM metallolyase superfamily; Region: DRE_TIM_metallolyase; cl07974
519441002135	Peptidase family U32; Region: Peptidase_U32; pfam01136
519441002136	metal binding site [ion binding]; metal-binding site
519441002137	Collagenase; Region: DUF3656; pfam12392
519441002138	Predicted RNA-binding protein containing KH domain, possibly ribosomal protein [Translation, ribosomal structure and biogenesis]; Region: COG1534
519441002139	Divergent PAP2 family; Region: DUF212; pfam02681
519441002140	Predicted rRNA methylase [Translation, ribosomal structure and biogenesis]; Region: COG1189
519441002141	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
519441002142	RNA binding surface [nucleotide binding]; other site
519441002143	FtsJ-like methyltransferase; Region: FtsJ; pfam01728
519441002144	Periplasmic protease [Cell envelope biogenesis, outer membrane]; Region: Prc; COG0793
519441002145	C-terminal processing peptidase family S41; Region: Peptidase_S41; cl02526
519441002146	PDZ domain of C-terminal processing-, tail-specific-, and tricorn proteases, which function in posttranslational protein processing, maturation, and disassembly or degradation, in Bacteria, Archaea, and plant chloroplasts. May be responsible for...; Region: PDZ_CTP_protease; cd00988
519441002147	protein binding site [polypeptide binding]; other site
519441002148	C-terminal processing peptidase; serine protease family S41; Region: Peptidase_S41_CPP; cd07560
519441002149	Catalytic dyad [active]
519441002150	Predicted methyltransferases [General function prediction only]; Region: COG0313
519441002151	Ribosomal RNA small subunit methyltransferase I, also known as rRNA (cytidine-2'-O-)-methyltransferase RsmI; Region: RsmI; cd11648
519441002152	putative SAM binding site [chemical binding]; other site
519441002153	putative homodimer interface [polypeptide binding]; other site
519441002154	ribosome biogenesis GTP-binding protein YlqF; Region: GTPase_YlqF; TIGR03596
519441002155	Circularly permuted YlqF GTPase; Region: YlqF; cd01856
519441002156	GTP/Mg2+ binding site [chemical binding]; other site
519441002157	G4 box; other site
519441002158	G5 box; other site
519441002159	50S ribosome-binding GTPase; Region: MMR_HSR1; pfam01926
519441002160	G1 box; other site
519441002161	Switch I region; other site
519441002162	G2 box; other site
519441002163	G3 box; other site
519441002164	Switch II region; other site
519441002165	helicase 45; Provisional; Region: PTZ00424
519441002166	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
519441002167	ATP binding site [chemical binding]; other site
519441002168	Mg++ binding site [ion binding]; other site
519441002169	motif III; other site
519441002170	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
519441002171	nucleotide binding region [chemical binding]; other site
519441002172	ATP-binding site [chemical binding]; other site
519441002173	RNA recognition motif in the DbpA subfamily of prokaryotic DEAD-box rRNA helicases; Region: RRM_DbpA; cd12252
519441002174	RNA binding site [nucleotide binding]; other site
519441002175	phosphoenolpyruvate carboxylase; Reviewed; Region: PRK00009
519441002176	Phosphoenolpyruvate carboxylase [Energy production and conversion]; Region: Ppc; COG2352
519441002177	tyrosyl-tRNA synthetase; Validated; Region: PRK05912
519441002178	catalytic core domain of tyrosinyl-tRNA synthetase; Region: TyrRS_core; cd00805
519441002179	active site
519441002180	HIGH motif; other site
519441002181	dimer interface [polypeptide binding]; other site
519441002182	KMSKS motif; other site
519441002183	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
519441002184	RNA binding surface [nucleotide binding]; other site
519441002185	thioredoxin-disulfide reductase; Region: TRX_reduct; TIGR01292
519441002186	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
519441002187	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
519441002188	Small protein B (SmpB) is a component of the trans-translation system in prokaryotes for releasing stalled ribosome from damaged messenger RNAs; Region: SmpB; cd09294
519441002189	SmpB-tmRNA interface; other site
519441002190	ribonuclease R; Region: RNase_R; TIGR02063
519441002191	RNB domain; Region: RNB; pfam00773
519441002192	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
519441002193	RNA binding site [nucleotide binding]; other site
519441002194	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
519441002195	Zn2+ binding site [ion binding]; other site
519441002196	Mg2+ binding site [ion binding]; other site
519441002197	N-acetylmuramoyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: AmiC; COG0860
519441002198	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696
519441002199	active site
519441002200	metal binding site [ion binding]; metal-binding site
519441002201	Preprotein translocase subunit; Region: YajC; pfam02699
519441002202	N-glycosylase/DNA lyase; Provisional; Region: PRK01229
519441002203	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
519441002204	minor groove reading motif; other site
519441002205	helix-hairpin-helix signature motif; other site
519441002206	active site
519441002207	Sulphur transport; Region: Sulf_transp; pfam04143
519441002208	SirA, YedF, and YeeD. Two-layered alpha/beta sandwich domain.  SirA (also known as UvrY,  and YhhP) belongs to a family of bacterial two-component response regulators that controls secondary metabolism and virulence. The other member of this...; Region: SirA_YedF_YeeD; cd00291
519441002209	CPxP  motif; other site
519441002210	Sulphur transport; Region: Sulf_transp; pfam04143
519441002211	Anaerobic glycerol-3-phosphate dehydrogenase [Amino acid transport and metabolism]; Region: GlpB; cl17730
519441002212	thioredoxin-disulfide reductase; Region: TRX_reduct; TIGR01292
519441002213	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
519441002214	SirA, YedF, and YeeD. Two-layered alpha/beta sandwich domain.  SirA (also known as UvrY,  and YhhP) belongs to a family of bacterial two-component response regulators that controls secondary metabolism and virulence. The other member of this...; Region: SirA_YedF_YeeD; cd00291
519441002215	CPxP  motif; other site
519441002216	Transcriptional regulator [Transcription]; Region: LysR; COG0583
519441002217	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
519441002218	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
519441002219	dimerization interface [polypeptide binding]; other site
519441002220	ABC transporter ATP-binding protein; Provisional; Region: PRK15064
519441002221	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
519441002222	Walker A/P-loop; other site
519441002223	ATP binding site [chemical binding]; other site
519441002224	Q-loop/lid; other site
519441002225	ABC transporter signature motif; other site
519441002226	Walker B; other site
519441002227	D-loop; other site
519441002228	H-loop/switch region; other site
519441002229	ABC transporter; Region: ABC_tran_2; pfam12848
519441002230	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
519441002231	ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+; Region: ADPRase_NUDT5; cd03424
519441002232	dimer interface [polypeptide binding]; other site
519441002233	ADP-ribose binding site [chemical binding]; other site
519441002234	active site
519441002235	nudix motif; other site
519441002236	metal binding site [ion binding]; metal-binding site
519441002237	Mg/Co/Ni transporter MgtE (contains CBS domain) [Inorganic ion transport and metabolism]; Region: MgtE; COG2239
519441002238	MgtE intracellular N domain; Region: MgtE_N; pfam03448
519441002239	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domain in the magnesium transporter, MgtE.  MgtE and its homologs are found in eubacteria, archaebacteria, and eukaryota. Members of this family transport Mg2+ or other...; Region: CBS_pair_Mg_transporter; cd04606
519441002240	Divalent cation transporter; Region: MgtE; cl00786
519441002241	Protein of unknown function DUF45; Region: DUF45; pfam01863
519441002242	Membrane protease subunits, stomatin/prohibitin homologs [Posttranslational modification, protein turnover, chaperones]; Region: HflC; COG0330
519441002243	SPFH domain / Band 7 family; Region: Band_7; pfam01145
519441002244	cyclophilin: cyclophilin-type peptidylprolyl cis- trans isomerases. This family contains eukaryotic, bacterial and archeal proteins which exhibit a peptidylprolyl cis- trans isomerases activity (PPIase, Rotamase) and in addition bind the...; Region: cyclophilin; cd00317
519441002245	active site
519441002246	Deoxynucleoside kinases [Nucleotide transport and metabolism]; Region: COG1428
519441002247	Deoxyribonucleoside kinase (dNK) catalyzes the phosphorylation of deoxyribonucleosides to yield corresponding monophosphates (dNMPs). This family consists of various deoxynucleoside kinases including deoxyribo- cytidine (EC 2.7.1.74), guanosine (EC 2.7.1; Region: dNK; cd01673
519441002248	Substrate-binding site [chemical binding]; other site
519441002249	Substrate specificity [chemical binding]; other site
519441002250	This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases superfamily  includes N type ATP PPases and ATP sulphurylases. It forms a apha/beta/apha fold which  binds to Adenosine group.  This subfamily; Region: Alpha_ANH_like_II; cd01993
519441002251	Ligand Binding Site [chemical binding]; other site
519441002252	TIGR00269 family protein; Region: TIGR00269
519441002253	bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase; Validated; Region: PRK05579
519441002254	Flavoprotein; Region: Flavoprotein; pfam02441
519441002255	DNA / pantothenate metabolism flavoprotein; Region: DFP; pfam04127
519441002256	Prokaryotic UGPase catalyses the synthesis of UDP-glucose; Region: UGPase_prokaryotic; cd02541
519441002257	dTDP-glucose pyrophosphorylase [Cell envelope biogenesis, outer membrane]; Region: RfbA; COG1209
519441002258	active site
519441002259	tetramer interface; other site
519441002260	tRNA pseudouridine synthase B; Provisional; Region: truB; PRK00130
519441002261	Pseudouridine synthase, Escherichia coli TruB like; Region: PseudoU_synth_EcTruB; cd02573
519441002262	RNA binding site [nucleotide binding]; other site
519441002263	active site
519441002264	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
519441002265	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
519441002266	dimerization interface [polypeptide binding]; other site
519441002267	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
519441002268	dimer interface [polypeptide binding]; other site
519441002269	phosphorylation site [posttranslational modification]
519441002270	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
519441002271	ATP binding site [chemical binding]; other site
519441002272	Mg2+ binding site [ion binding]; other site
519441002273	G-X-G motif; other site
519441002274	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
519441002275	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
519441002276	active site
519441002277	phosphorylation site [posttranslational modification]
519441002278	intermolecular recognition site; other site
519441002279	dimerization interface [polypeptide binding]; other site
519441002280	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
519441002281	DNA binding site [nucleotide binding]
519441002282	putative protease; Provisional; Region: PRK15452
519441002283	DRE-TIM metallolyase superfamily; Region: DRE_TIM_metallolyase; cl07974
519441002284	Peptidase family U32; Region: Peptidase_U32; pfam01136
519441002285	metal binding site [ion binding]; metal-binding site
519441002286	DnaB-like helicase N terminal domain; Region: DnaB; pfam00772
519441002287	replicative DNA helicase; Region: DnaB; TIGR00665
519441002288	DnaB helicase C terminal domain. The hexameric helicase DnaB unwinds the DNA duplex at the  chromosome replication fork. Although the mechanism by which DnaB both couples ATP hydrolysis to translocation along DNA and denatures the duplex is unknown, a...; Region: DnaB_C; cd00984
519441002289	Walker A motif; other site
519441002290	ATP binding site [chemical binding]; other site
519441002291	Walker B motif; other site
519441002292	DNA binding loops [nucleotide binding]
519441002293	Ribosomal protein L9, N-terminal domain; Region: Ribosomal_L9_N; pfam01281
519441002294	50S ribosomal protein L9; Reviewed; Region: rplI; PRK00137
519441002295	Ribosomal protein L9, C-terminal domain; Region: Ribosomal_L9_C; pfam03948
519441002296	DNA polymerase III, subunit gamma and tau; Region: dnaX_nterm; TIGR02397
519441002297	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
519441002298	Walker A motif; other site
519441002299	ATP binding site [chemical binding]; other site
519441002300	DNA polymerase III subunit delta'; Validated; Region: PRK08485
519441002301	Walker B motif; other site
519441002302	arginine finger; other site
519441002303	NAD(P) binding domain of Shikimate dehydrogenase; Region: NAD_bind_Shikimate_DH; cd01065
519441002304	NAD(P) binding site [chemical binding]; other site
519441002305	16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases [Translation, ribosomal structure and biogenesis]; Region: RsuA; COG1187
519441002306	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
519441002307	RNA binding surface [nucleotide binding]; other site
519441002308	Pseudouridine synthase, Escherichia coli RsuA like; Region: PseudoU_synth_RsuA; cd02553
519441002309	active site
519441002310	uracil binding [chemical binding]; other site
519441002311	ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms]; Region: SalY; COG0577
519441002312	FtsX-like permease family; Region: FtsX; pfam02687
519441002313	thymidine kinase; Provisional; Region: PRK04296
519441002314	Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]; Region: Spr; COG0791
519441002315	NlpC/P60 family; Region: NLPC_P60; pfam00877
519441002316	Uncharacterized protein related to glutamine synthetase [General function prediction only]; Region: COG3968
519441002317	Glutamine synthetase type III N terminal; Region: GSIII_N; pfam12437
519441002318	Glutamine synthetase, catalytic domain; Region: Gln-synt_C; pfam00120
519441002319	Predicted membrane protein [Function unknown]; Region: COG2860
519441002320	UPF0126 domain; Region: UPF0126; pfam03458
519441002321	UPF0126 domain; Region: UPF0126; pfam03458
519441002322	DNA polymerase III, epsilon subunit and related 3'-5' exonucleases [DNA replication, recombination, and repair]; Region: DnaQ; COG0847
519441002323	DEDDh 3'-5' exonuclease domain family; Region: DEDDh; cd06127
519441002324	active site
519441002325	catalytic site [active]
519441002326	substrate binding site [chemical binding]; other site
519441002327	GTP-binding protein LepA; Provisional; Region: PRK05433
519441002328	LepA also known as Elongation Factor 4 (EF4); Region: LepA; cd01890
519441002329	G1 box; other site
519441002330	putative GEF interaction site [polypeptide binding]; other site
519441002331	GTP/Mg2+ binding site [chemical binding]; other site
519441002332	Switch I region; other site
519441002333	G2 box; other site
519441002334	G3 box; other site
519441002335	Switch II region; other site
519441002336	G4 box; other site
519441002337	G5 box; other site
519441002338	lepA_II: This subfamily represents the domain II of LepA, a GTP-binding protein localized in the cytoplasmic membrane. The N-terminal domain of LepA shares regions of homology to translation factors. In terms of interaction with the ribosome, EF-G, EF-Tu...; Region: lepA_II; cd03699
519441002339	lepA_C: This family represents the C-terminal region of LepA, a GTP-binding protein localized in the cytoplasmic membrane.   LepA is ubiquitous in Bacteria and Eukaryota (e.g. Saccharomyces cerevisiae GUF1p), but is missing from Archaea. LepA exhibits...; Region: lepA_C; cd03709
519441002340	GTP-binding protein LepA C-terminus; Region: LepA_C; pfam06421
519441002341	Large-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscL; COG1970
519441002342	large-conductance mechanosensitive channel; Reviewed; Region: mscL; PRK00567
519441002343	cyclophilin: cyclophilin-type peptidylprolyl cis- trans isomerases. This family contains eukaryotic, bacterial and archeal proteins which exhibit a peptidylprolyl cis- trans isomerases activity (PPIase, Rotamase) and in addition bind the...; Region: cyclophilin; cd00317
519441002344	active site
519441002345	Maf-like protein; Region: Maf; pfam02545
519441002346	Nucleotide binding protein Maf. Maf has been implicated in inhibition of septum formation in eukaryotes, bacteria and archaea, but homologs in B.subtilis and S.cerevisiae are nonessential for cell division. Maf has been predicted to be a nucleotide- or...; Region: Maf; cd00555
519441002347	active site
519441002348	dimer interface [polypeptide binding]; other site
519441002349	purine nucleoside phosphorylase; Provisional; Region: PRK08202
519441002350	Uncharacterized membrane protein, putative virulence factor [General function prediction only]; Region: MviN; COG0728
519441002351	MurJ/MviN, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Region: MATE_MurJ_like; cd13123
519441002352	ScpA/B protein; Region: ScpA_ScpB; cl00598
519441002353	bifunctional riboflavin kinase/FMN adenylyltransferase; Reviewed; Region: PRK05627
519441002354	FAD synthetase, N-terminal domain of the bifunctional enzyme; Region: FAD_synthetase_N; cd02064
519441002355	active site
519441002356	Riboflavin kinase; Region: Flavokinase; pfam01687
519441002357	ATP-dependent Lon protease, bacterial type [Posttranslational modification, protein turnover, chaperones]; Region: Lon; COG0466
519441002358	Found in ATP-dependent protease La (LON); Region: LON; smart00464
519441002359	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
519441002360	Walker A motif; other site
519441002361	ATP binding site [chemical binding]; other site
519441002362	Walker B motif; other site
519441002363	arginine finger; other site
519441002364	Lon protease (S16) C-terminal proteolytic domain; Region: Lon_C; pfam05362
519441002365	ATP-dependent protease ATP-binding subunit ClpX; Provisional; Region: clpX; PRK05342
519441002366	ClpX C4-type zinc finger; Region: zf-C4_ClpX; pfam06689
519441002367	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
519441002368	Walker A motif; other site
519441002369	ATP binding site [chemical binding]; other site
519441002370	Walker B motif; other site
519441002371	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
519441002372	Clp protease; Region: CLP_protease; pfam00574
519441002373	Caseinolytic protease (ClpP) is an ATP-dependent, highly conserved serine protease; Region: S14_ClpP_2; cd07017
519441002374	oligomer interface [polypeptide binding]; other site
519441002375	active site residues [active]
519441002376	trigger factor; Region: tig; TIGR00115
519441002377	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
519441002378	Bacterial trigger factor protein (TF) C-terminus; Region: Trigger_C; pfam05698
519441002379	single-stranded-DNA-specific exonuclease RecJ; Region: recJ; TIGR00644
519441002380	DHH family; Region: DHH; pfam01368
519441002381	DHHA1 domain; Region: DHHA1; pfam02272
519441002382	Ribosome-binding factor A; Region: RBFA; pfam02033
519441002383	Translation initiation factor IF-2, N-terminal region; Region: IF2_N; pfam04760
519441002384	Translation initiation factor IF-2, N-terminal region; Region: IF2_N; pfam04760
519441002385	Translation initiation factor 2 (IF-2; GTPase) [Translation, ribosomal structure and biogenesis]; Region: InfB; COG0532
519441002386	Initiation Factor 2 (IF2)/ eukaryotic Initiation Factor 5B (eIF5B) family; Region: IF2_eIF5B; cd01887
519441002387	G1 box; other site
519441002388	putative GEF interaction site [polypeptide binding]; other site
519441002389	GTP/Mg2+ binding site [chemical binding]; other site
519441002390	Switch I region; other site
519441002391	G2 box; other site
519441002392	G3 box; other site
519441002393	Switch II region; other site
519441002394	G4 box; other site
519441002395	G5 box; other site
519441002396	This family represents the domain II of bacterial Initiation Factor 2 (IF2) and its eukaryotic mitochondrial homologue mtIF2. IF2, the largest initiation factor is an essential GTP binding protein. In E. coli three natural forms of IF2 exist in the cell; Region: IF2_mtIF2_II; cd03702
519441002397	Translation-initiation factor 2; Region: IF-2; pfam11987
519441002398	mtIF2_IVc: this family represents the C2 subdomain of domain IV of mitochondrial translation initiation factor 2 (mtIF2) which adopts a beta-barrel fold displaying a high degree of structural similarity with domain II of the translation elongation factor...; Region: mtIF2_IVc; cd03692
519441002399	Protein of unknown function (DUF448); Region: DUF448; pfam04296
519441002400	putative RNA binding cleft [nucleotide binding]; other site
519441002401	transcription elongation factor NusA; Provisional; Region: nusA; PRK12327
519441002402	NusA N-terminal domain; Region: NusA_N; pfam08529
519441002403	S1_NusA: N-utilizing substance A protein (NusA), S1-like RNA-binding domain. S1-like RNA-binding domains are found in a wide variety of RNA-associated proteins. NusA is a transcription elongation factor containing an N-terminal catalytic domain and three...; Region: S1_NusA; cd04455
519441002404	RNA binding site [nucleotide binding]; other site
519441002405	homodimer interface [polypeptide binding]; other site
519441002406	NusA-like KH domain; Region: KH_5; pfam13184
519441002407	NusA_K homology RNA-binding domain (KH). NusA is an essential multifunctional transcription elongation factor that is universally conserved among prokaryotes and archaea. NusA anti-termination function plays an important role in the expression of...; Region: NusA_KH; cd02134
519441002408	G-X-X-G motif; other site
519441002409	Uncharacterized BCR, YhbC family COG0779; Region: DUF150; pfam02576
519441002410	Sm and related proteins; Region: Sm_like; cl00259
519441002411	Bacillus subtilis YxlS-like, C-terminal domain; Region: YlxS_C; cd01734
519441002412	putative oligomer interface [polypeptide binding]; other site
519441002413	putative RNA binding site [nucleotide binding]; other site
519441002414	hypothetical protein; Validated; Region: PRK00110
519441002415	DNA integrity scanning protein DisA; Provisional; Region: PRK13482
519441002416	DisA bacterial checkpoint controller nucleotide-binding; Region: DisA_N; pfam02457
519441002417	DisA bacterial checkpoint controller linker region; Region: DisA-linker; pfam10635
519441002418	DNA repair protein RadA; Provisional; Region: PRK11823
519441002419	Sms (bacterial radA) DNA repair protein. This protein is not related to archael radA any more than is to other RecA-like NTPases. Sms has a role in recombination and recombinational repair and is responsible for the stabilization or processing of...; Region: Sms; cd01121
519441002420	Walker A motif/ATP binding site; other site
519441002421	ATP binding site [chemical binding]; other site
519441002422	Walker B motif; other site
519441002423	Lon protease (S16) C-terminal proteolytic domain; Region: Lon_C; pfam05362
519441002424	phosphopantetheine adenylyltransferase; Provisional; Region: coaD; PRK00168
519441002425	Phosphopantetheine adenylyltransferase; Region: PPAT; cd02163
519441002426	active site
519441002427	(T/H)XGH motif; other site
519441002428	ribonuclease III; Reviewed; Region: rnc; PRK00102
519441002429	RIBOc. Ribonuclease III C terminal domain. This group consists of eukaryotic, bacterial and archeal ribonuclease III (RNAse III) proteins. RNAse III is a double stranded RNA-specific endonuclease. Prokaryotic RNAse III is important in...; Region: RIBOc; cd00593
519441002430	dimerization interface [polypeptide binding]; other site
519441002431	active site
519441002432	metal binding site [ion binding]; metal-binding site
519441002433	Double-stranded RNA binding motif. Binding is not sequence specific but is highly specific for double stranded RNA. Found in a variety of proteins including dsRNA dependent protein kinase PKR, RNA helicases, Drosophila staufen protein, E. coli RNase III; Region: DSRM; cd00048
519441002434	dsRNA binding site [nucleotide binding]; other site
519441002435	Phosphopantetheine attachment site; Region: PP-binding; cl09936
519441002436	HAD superfamily (subfamily IA) hydrolase, TIGR02254; Region: YjjG/YfnB
519441002437	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
519441002438	glycogen synthase; Provisional; Region: glgA; PRK00654
519441002439	This family is most closely related to the GT1 family of glycosyltransferases. Glycogen synthase catalyzes the formation and elongation of the alpha-1,4-glucose backbone using ADP-glucose, the second and key step of glycogen biosynthesis. This family...; Region: GT1_Glycogen_synthase_DULL1_like; cd03791
519441002440	ADP-binding pocket [chemical binding]; other site
519441002441	homodimer interface [polypeptide binding]; other site
519441002442	glucose-1-phosphate adenylyltransferase; Provisional; Region: glgC; PRK05293
519441002443	ADP-glucose pyrophosphorylase is involved in the biosynthesis of glycogen or starch; Region: ADP_Glucose_PP; cd02508
519441002444	ligand binding site; other site
519441002445	oligomer interface; other site
519441002446	Glucose-1-phosphate adenylyltransferase, C-terminal Left-handed parallel beta helix (LbH) domain: Glucose-1-phosphate adenylyltransferase is also known as ADP-glucose synthase or ADP-glucose pyrophosphorylase. It catalyzes the first committed and...; Region: LbH_G1P_AT_C; cd04651
519441002447	dimer interface [polypeptide binding]; other site
519441002448	N-terminal domain interface [polypeptide binding]; other site
519441002449	sulfate 1 binding site; other site
519441002450	2-methylthioadenine synthetase [Translation, ribosomal structure and biogenesis]; Region: MiaB; COG0621
519441002451	Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919
519441002452	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
519441002453	FeS/SAM binding site; other site
519441002454	TRAM domain; Region: TRAM; pfam01938
519441002455	Formate/nitrite transporter; Region: Form_Nir_trans; pfam01226
519441002456	Human Ape1-like subfamily of the ExoIII family purinic/apyrimidinic (AP) endonucleases; Region: Ape1-like_AP-endo; cd09087
519441002457	active site
519441002458	putative catalytic site [active]
519441002459	DNA binding site [nucleotide binding]
519441002460	putative phosphate binding site [ion binding]; other site
519441002461	metal binding site A [ion binding]; metal-binding site
519441002462	AP binding site [nucleotide binding]; other site
519441002463	metal binding site B [ion binding]; metal-binding site
519441002464	16S rRNA m(4)C1402 methyltranserfase; Provisional; Region: PRK00050
519441002465	MraW methylase family; Region: Methyltransf_5; pfam01795
519441002466	cell division protein MraZ; Reviewed; Region: PRK00326
519441002467	MraZ protein; Region: MraZ; pfam02381
519441002468	MraZ protein; Region: MraZ; pfam02381
519441002469	This is a family of oligosaccharide phosphorylases. It includes yeast and mammalian glycogen phosphorylases, plant starch/glucan phosphorylase, as well as the maltodextrin phosphorylases of bacteria. The members of this family catalyze the breakdown of...; Region: GT1_Glycogen_Phosphorylase; cd04300
519441002470	homodimer interface [polypeptide binding]; other site
519441002471	glycogen/starch/alpha-glucan phosphorylases; Region: P_ylase; TIGR02093
519441002472	active site pocket [active]
519441002473	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
519441002474	IHF - DNA interface [nucleotide binding]; other site
519441002475	IHF dimer interface [polypeptide binding]; other site
519441002476	triosephosphate isomerase; Provisional; Region: PRK14567
519441002477	Triosephosphate isomerase (TIM) is a glycolytic enzyme that catalyzes the interconversion of dihydroxyacetone phosphate and D-glyceraldehyde-3-phosphate. The reaction is very efficient and requires neither cofactors nor metal ions. TIM, usually...; Region: TIM; cd00311
519441002478	substrate binding site [chemical binding]; other site
519441002479	dimer interface [polypeptide binding]; other site
519441002480	catalytic triad [active]
519441002481	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
519441002482	haloacid dehalogenase-like hydrolase; Region: Hydrolase_3; pfam08282
519441002483	active site
519441002484	motif I; other site
519441002485	motif II; other site
519441002486	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
519441002487	Methylated DNA-protein cysteine methyltransferase [DNA replication, recombination, and repair]; Region: Ada; COG0350
519441002488	The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445
519441002489	DNA binding site [nucleotide binding]
519441002490	active site
519441002491	acetate kinase A/propionate kinase 2; Reviewed; Region: PRK00180
519441002492	propionate/acetate kinase; Provisional; Region: PRK12379
519441002493	Hemolysins and related proteins containing CBS domains [General function prediction only]; Region: TlyC; COG1253
519441002494	Domain of unknown function DUF21; Region: DUF21; pfam01595
519441002495	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
519441002496	Transporter associated domain; Region: CorC_HlyC; smart01091
519441002497	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
519441002498	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
519441002499	nucleotide binding site [chemical binding]; other site
519441002500	BadF/BadG/BcrA/BcrD ATPase family; Region: BcrAD_BadFG; cl17271
519441002501	Aldehyde dehydrogenase family; Region: Aldedh; pfam00171
519441002502	NADP+-dependent non-phosphorylating glyceraldehyde 3-phosphate dehydrogenase and ALDH family 11; Region: ALDH_F11_NP-GAPDH; cd07082
519441002503	tetrameric interface [polypeptide binding]; other site
519441002504	activator binding site; other site
519441002505	NADP binding site [chemical binding]; other site
519441002506	substrate binding site [chemical binding]; other site
519441002507	catalytic residues [active]
519441002508	Lysophospholipase [Lipid metabolism]; Region: PldB; COG2267
519441002509	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
519441002510	Cation transport ATPase [Inorganic ion transport and metabolism]; Region: ZntA; COG2217
519441002511	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
519441002512	metal-binding site [ion binding]
519441002513	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
519441002514	Soluble P-type ATPase [General function prediction only]; Region: COG4087
519441002515	Transposase zinc-binding domain; Region: Zn_Tnp_IS91; pfam14319
519441002516	Putative transposase; Region: Y2_Tnp; pfam04986
519441002517	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
519441002518	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
519441002519	catalytic residues [active]
519441002520	coenzyme A disulfide reductase; Reviewed; Region: PRK09564
519441002521	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
519441002522	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
519441002523	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
519441002524	tRNA dihydrouridine synthase A; Region: yjbN; TIGR00742
519441002525	Dihydrouridine synthase-like (DUS-like) FMN-binding domain. Members of this family catalyze the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also...; Region: DUS_like_FMN; cd02801
519441002526	FMN binding site [chemical binding]; other site
519441002527	active site
519441002528	catalytic residues [active]
519441002529	substrate binding site [chemical binding]; other site
519441002530	Protein of unknown function, DUF606; Region: DUF606; pfam04657
519441002531	recombination factor protein RarA; Reviewed; Region: PRK13342
519441002532	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
519441002533	Walker A motif; other site
519441002534	ATP binding site [chemical binding]; other site
519441002535	Walker B motif; other site
519441002536	arginine finger; other site
519441002537	MgsA AAA+ ATPase C terminal; Region: MgsA_C; pfam12002
519441002538	4-alpha-glucanotransferase; Provisional; Region: PRK14508
519441002539	RmuC family; Region: RmuC; pfam02646
519441002540	Virulence factor BrkB; Region: Virul_fac_BrkB; pfam03631
519441002541	thiamine biosynthesis protein ThiI; Provisional; Region: PRK01565
519441002542	THUMP domain of thiamine biosynthesis protein ThiI; Region: THUMP_ThiI; cd11716
519441002543	ThiI is required for thiazole synthesis in the thiamine biosynthesis pathway. It belongs to the Adenosine Nucleotide Hydrolysis suoerfamily and predicted to bind to Adenosine nucleotide; Region: ThiI; cd01712
519441002544	Ligand Binding Site [chemical binding]; other site
519441002545	queuine tRNA-ribosyltransferase; Provisional; Region: tgt; PRK00112
519441002546	Queuine/archaeosine tRNA-ribosyltransferase [Translation, ribosomal structure and biogenesis]; Region: Tgt; COG0343
519441002547	Guanosine polyphosphate pyrophosphohydrolases/synthetases [Signal transduction mechanisms / Transcription]; Region: SpoT; COG0317
519441002548	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
519441002549	Zn2+ binding site [ion binding]; other site
519441002550	Mg2+ binding site [ion binding]; other site
519441002551	Nucleotidyltransferase (NT) domain of RelA- and SpoT-like ppGpp synthetases and hydrolases; Region: NT_Rel-Spo_like; cd05399
519441002552	synthetase active site [active]
519441002553	NTP binding site [chemical binding]; other site
519441002554	metal binding site [ion binding]; metal-binding site
519441002555	TGS_RelA_SpoT: The RelA (SpoT) protein, also referred to as ppGpp hydrolase/synthetase, is a ribosome-associated protein that is activated during amino acid starvation and thought to mediate the stringent response. RelA contains a TGS domain, named after...; Region: TGS_RelA_SpoT; cd01668
519441002556	ACT domain; Region: ACT_4; pfam13291
519441002557	Pertactin-like passenger domains (virulence factors) of autotransporter proteins of the type V secretion system. Autotransporters are proteins used by Gram-negative bacteria to transport proteins across their outer membranes. The C-terminal (beta) domain...; Region: PL_Passenger_AT; cd00253
519441002558	outer membrane autotransporter barrel domain; Region: autotrans_barl; TIGR01414
519441002559	Autotransporter beta-domain; Region: Autotransporter; pfam03797
519441002560	Pertactin-like passenger domains (virulence factors) of autotransporter proteins of the type V secretion system. Autotransporters are proteins used by Gram-negative bacteria to transport proteins across their outer membranes. The C-terminal (beta) domain...; Region: PL_Passenger_AT; cd00253
519441002561	outer membrane autotransporter barrel domain; Region: autotrans_barl; TIGR01414
519441002562	Autotransporter beta-domain; Region: Autotransporter; cl17461
519441002563	Transposase zinc-binding domain; Region: Zn_Tnp_IS91; pfam14319
519441002564	Putative transposase; Region: Y2_Tnp; pfam04986
519441002565	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
519441002566	This family is most closely related to the GT1 family of glycosyltransferases. UDP-glucose-diacylglycerol glucosyltransferase (UGDG; also known as 1,2-diacylglycerol 3-glucosyltransferase) catalyzes the transfer of glucose from UDP-glucose to 1; Region: GT1_UGDG_like; cd03817
519441002567	putative ADP-binding pocket [chemical binding]; other site
519441002568	5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Validated; Region: PRK05584
519441002569	5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Region: MTA/SAH-Nsdase; TIGR01704
519441002570	DNA-binding ferritin-like protein (oxidative damage protectant) [Inorganic ion transport and metabolism]; Region: Dps; COG0783
519441002571	DPS protein, ferritin-like diiron-binding domain; Region: DPS; cd01043
519441002572	dimerization interface [polypeptide binding]; other site
519441002573	DPS ferroxidase diiron center [ion binding]; other site
519441002574	ion pore; other site
519441002575	RaiA ("ribosome-associated inhibitor A", also known as Protein Y (PY), YfiA, and SpotY,  is a stress-response protein that binds the ribosomal subunit interface and arrests translation by interfering with aminoacyl-tRNA binding to the ribosomal...; Region: RaiA; cd00552
519441002576	30S subunit binding site; other site
519441002577	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
519441002578	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
519441002579	Walker A/P-loop; other site
519441002580	ATP binding site [chemical binding]; other site
519441002581	Q-loop/lid; other site
519441002582	ABC transporter signature motif; other site
519441002583	Walker B; other site
519441002584	D-loop; other site
519441002585	H-loop/switch region; other site
519441002586	ABC-type transport system, involved in lipoprotein release, permease component [Cell envelope biogenesis, outer membrane]; Region: LolE; COG4591
519441002587	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
519441002588	FtsX-like permease family; Region: FtsX; pfam02687
519441002589	transcriptional regulator NrdR; Validated; Region: nrdR; PRK00464
519441002590	ATP cone domain; Region: ATP-cone; pfam03477
519441002591	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
519441002592	active site
519441002593	phosphorylation site [posttranslational modification]
519441002594	DNA repair protein RecO; Reviewed; Region: recO; PRK00085
519441002595	Recombination protein O N terminal; Region: RecO_N; pfam11967
519441002596	rod shape-determining protein MreC; Provisional; Region: PRK13922
519441002597	rod shape-determining protein MreC; Region: MreC; pfam04085
519441002598	chaperonin GroEL; Reviewed; Region: groEL; PRK12849
519441002599	GroEL_like type I chaperonin. Chaperonins are involved in productive folding of proteins. They share a common general morphology, a double toroid of 2 stacked rings, each composed of 7-9 subunits. The symmetry of type I is seven-fold and they are found...; Region: GroEL; cd03344
519441002600	ring oligomerisation interface [polypeptide binding]; other site
519441002601	ATP/Mg binding site [chemical binding]; other site
519441002602	stacking interactions; other site
519441002603	hinge regions; other site
519441002604	Chaperonin 10 Kd subunit (cpn10 or GroES); Cpn10 cooperates with chaperonin 60 (cpn60 or GroEL), an ATPase, to assist the folding and assembly of proteins and is found in eubacterial cytosol, as well as in the matrix of mitochondria and chloroplasts. It...; Region: cpn10; cd00320
519441002605	oligomerisation interface [polypeptide binding]; other site
519441002606	mobile loop; other site
519441002607	roof hairpin; other site
519441002608	Peptidase domain in the S8 and S53 families; Region: Peptidases_S8_S53; cl10459
519441002609	catalytic residues [active]
519441002610	Autotransporter-associated beta strand repeat; Region: Autotrns_rpt; cl15373
519441002611	DJ-1 family protein; Region: not_thiJ; TIGR01383
519441002612	Type 1 glutamine amidotransferase (GATase1)-like domain found in Human DJ-1; Region: GATase1_DJ-1; cd03135
519441002613	conserved cys residue [active]
519441002614	Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) [Carbohydrate transport and metabolism]; Region: PtsA; COG1080
519441002615	PEP-utilising enzyme, N-terminal; Region: PEP-utilisers_N; pfam05524
519441002616	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
519441002617	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
519441002618	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
519441002619	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
519441002620	tRNA (guanine-N(1)-)-methyltransferase; Reviewed; Region: trmD; PRK00026
519441002621	16S rRNA-processing protein RimM; Provisional; Region: rimM; PRK00122
519441002622	RimM N-terminal domain; Region: RimM; pfam01782
519441002623	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cl00025
519441002624	SAM-dependent RNA methyltransferase; Region: Methyltrn_RNA_4; pfam09936
519441002625	tRNA nucleotidyltransferase/poly(A) polymerase [Translation, ribosomal structure and biogenesis]; Region: PcnB; COG0617
519441002626	Nucleotidyltransferase (NT) domain of ClassII CCA-adding enzymes; Region: NT_ClassII-CCAase; cd05398
519441002627	active site
519441002628	NTP binding site [chemical binding]; other site
519441002629	metal binding triad [ion binding]; metal-binding site
519441002630	Probable RNA and SrmB- binding site of polymerase A; Region: PolyA_pol_RNAbd; pfam12627
519441002631	Diadenosine tetraphosphate (Ap4A) hydrolase is a member of the Nudix hydrolase superfamily. Ap4A hydrolases are well represented in a variety of prokaryotic and eukaryotic organisms. Phylogenetic analysis reveals two distinct subgroups where plant...; Region: Ap4A_hydrolase_human_like; cd03428
519441002632	active site
519441002633	Ap4A binding cleft/pocket [chemical binding]; other site
519441002634	P4 phosphate binding site; other site
519441002635	nudix motif; other site
519441002636	putative P2/P3 phosphate binding site [ion binding]; other site
519441002637	NusB family; Region: NusB; pfam01029
519441002638	16S rRNA methyltransferase B; Provisional; Region: PRK14902
519441002639	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
519441002640	S-adenosylmethionine binding site [chemical binding]; other site
519441002641	tRNA methyl transferase; Region: tRNA_Me_trans; pfam03054
519441002642	tRNA methyl transferase. This family represents tRNA(5-methylaminomethyl-2-thiouridine)-methyltransferase which is involved in the biosynthesis of the modified nucleoside 5-methylaminomethyl-2-thiouridine present in the wobble position of some tRNAs; Region: tRNA_Me_trans; cd01998
519441002643	Ligand Binding Site [chemical binding]; other site
519441002644	YbaK-like.  The YbaK family of deacylase domains includes the INS amino acid-editing domain of  the bacterial class II prolyl tRNA synthetase (ProRS), and it's trans-acting homologs, YbaK, ProX, and PrdX. The primary function of INS is to hydrolyze...; Region: YbaK_like; cl00022
519441002645	putative deacylase active site [active]
519441002646	Transposase zinc-binding domain; Region: Zn_Tnp_IS91; pfam14319
519441002647	Putative transposase; Region: Y2_Tnp; pfam04986
519441002648	Replication initiator protein A (RepA) N-terminus; Region: RepA_N; pfam06970
519441002649	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
519441002650	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
519441002651	non-specific DNA binding site [nucleotide binding]; other site
519441002652	salt bridge; other site
519441002653	sequence-specific DNA binding site [nucleotide binding]; other site
519441002654	DNA breaking-rejoining enzymes, intergrase/recombinases, C-terminal catalytic domain. The tyrosine recombinase/integrase family share the same catalytic domain containing six conserved active site residues. The best-studied members of this diverse family...; Region: INT_REC_C; cd01182
519441002655	active site
519441002656	catalytic residues [active]
519441002657	DNA binding site [nucleotide binding]
519441002658	Int/Topo IB signature motif; other site
519441002659	Topoisomerase IA [DNA replication, recombination, and repair]; Region: TopA; COG0550
519441002660	TOPRIM_TopoIA_TopoIII: The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to topoisomerase III. Type IA DNA topoisomerases remove (relax) negative supercoils in the DNA by: cleaving...; Region: TOPRIM_TopoIA_TopoIII; cd03362
519441002661	active site
519441002662	putative interdomain interaction site [polypeptide binding]; other site
519441002663	putative metal-binding site [ion binding]; other site
519441002664	putative nucleotide binding site [chemical binding]; other site
519441002665	DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cl11986
519441002666	domain I; other site
519441002667	DNA binding groove [nucleotide binding]
519441002668	phosphate binding site [ion binding]; other site
519441002669	domain II; other site
519441002670	domain III; other site
519441002671	nucleotide binding site [chemical binding]; other site
519441002672	catalytic site [active]
519441002673	domain IV; other site
519441002674	Protein of unknown function (DUF3991); Region: DUF3991; pfam13154
519441002675	Toprim-like; Region: Toprim_2; pfam13155
519441002676	Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]; Region: Spr; COG0791
519441002677	NlpC/P60 family; Region: NLPC_P60; pfam00877
519441002678	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
519441002679	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
519441002680	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
519441002681	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
519441002682	YadA-like C-terminal region; Region: YadA; pfam03895
519441002683	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
519441002684	Outer membrane protein and related peptidoglycan-associated (lipo)proteins [Cell envelope biogenesis, outer membrane]; Region: OmpA; COG2885
519441002685	ligand binding site [chemical binding]; other site
519441002686	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
519441002687	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
519441002688	Protein of unknown function DUF2620; Region: DUF2620; pfam10941
519441002689	Ataxin-1 and HBP1 module (AXH); Region: AXH; cl02647
519441002690	Conjugal transfer protein TraD; Region: TraD; cl05753
519441002691	Type IV secretory pathway, protease TraF [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: TraF; COG4959
519441002692	Uncharacterized virulence-associated protein D [Function unknown]; Region: VapD; COG3309
519441002693	conjugal transfer ATPase TrbE; Provisional; Region: PRK13873
519441002694	CagE, TrbE, VirB family, component of type IV transporter system; Region: CagE_TrbE_VirB; pfam03135
519441002695	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
519441002696	Walker A motif; other site
519441002697	ATP binding site [chemical binding]; other site
519441002698	YadA-like C-terminal region; Region: YadA; pfam03895
519441002699	P-type conjugative transfer ATPase TrbB; Region: TrbB_P; TIGR02782
519441002700	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
519441002701	Walker A motif; other site
519441002702	ATP binding site [chemical binding]; other site
519441002703	Walker B motif; other site
519441002704	Type IV secretory system Conjugative DNA transfer; Region: T4SS-DNA_transf; pfam02534
519441002705	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
519441002706	Walker A motif; other site
519441002707	ATP binding site [chemical binding]; other site
519441002708	Walker B motif; other site
519441002709	Bacterial conjugation TrbI-like protein; Region: TrbI; pfam03743
519441002710	VirB9/CagX/TrbG, a component of the type IV secretion system; Region: VirB9_CagX_TrbG; cd06911
519441002711	VirB7 interaction site; other site
519441002712	VirB8 protein; Region: VirB8; pfam04335
519441002713	MobA/MobL family; Region: MobA_MobL; pfam03389
519441002714	BRO family, N-terminal domain; Region: Bro-N; smart01040
519441002715	Protein of unknown function (DUF739); Region: DUF739; pfam05339
519441002716	Replication initiator protein A (RepA) N-terminus; Region: RepA_N; pfam06970
519441002717	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
519441002718	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
519441002719	non-specific DNA binding site [nucleotide binding]; other site
519441002720	salt bridge; other site
519441002721	sequence-specific DNA binding site [nucleotide binding]; other site
519441002722	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
519441002723	non-specific DNA binding site [nucleotide binding]; other site
519441002724	salt bridge; other site
519441002725	sequence-specific DNA binding site [nucleotide binding]; other site
519441002726	DNA breaking-rejoining enzymes, intergrase/recombinases, C-terminal catalytic domain. The tyrosine recombinase/integrase family share the same catalytic domain containing six conserved active site residues. The best-studied members of this diverse family...; Region: INT_REC_C; cd01182
519441002727	active site
519441002728	catalytic residues [active]
519441002729	DNA binding site [nucleotide binding]
519441002730	Int/Topo IB signature motif; other site
519441002731	50S ribosomal protein L19; Provisional; Region: rplS; PRK05338
519441002732	Uncharacterized conserved protein [Function unknown]; Region: COG1284
519441002733	Uncharacterized BCR, YitT family COG1284; Region: DUF161; pfam02588
519441002734	Uncharacterized protein conserved in bacteria (DUF2179); Region: DUF2179; pfam10035
519441002735	Uncharacterized member of the PurR regulon [General function prediction only]; Region: yhhQ; COG1738
519441002736	chromosome segregation protein SMC, common bacterial type; Region: SMC_prok_B; TIGR02168
519441002737	ATP-binding cassette domain of barmotin, a member of the SMC protein family; Region: ABC_SMC_barmotin; cd03278
519441002738	Walker A/P-loop; other site
519441002739	ATP binding site [chemical binding]; other site
519441002740	Q-loop/lid; other site
519441002741	SMC proteins Flexible Hinge Domain; Region: SMC_hinge; pfam06470
519441002742	ATP-binding cassette domain of barmotin, a member of the SMC protein family; Region: ABC_SMC_barmotin; cd03278
519441002743	ABC transporter signature motif; other site
519441002744	Walker B; other site
519441002745	D-loop; other site
519441002746	H-loop/switch region; other site
519441002747	Deoxycytidylate deaminase domain. Deoxycytidylate deaminase catalyzes the deamination of dCMP to dUMP, providing the nucleotide substrate for thymidylate synthase. The enzyme binds Zn++, which is required for catalytic activity. The activity of the...; Region: deoxycytidylate_deaminase; cd01286
519441002748	catalytic motif [active]
519441002749	Zn binding site [ion binding]; other site
519441002750	exodeoxyribonuclease VII large subunit; Reviewed; Region: xseA; PRK00286
519441002751	ExoVII_LU_OBF: A subfamily of OB folds corresponding to the N-terminal OB-fold domain of Escherichia coli exodeoxyribonuclease VII (ExoVII) large subunit. E. coli ExoVII is composed of two non-identical subunits. E. coli ExoVII is a...; Region: ExoVII_LU_OBF; cd04489
519441002752	generic binding surface II; other site
519441002753	generic binding surface I; other site
519441002754	Arsenate Reductase (ArsC) family, unknown subfamily; uncharacterized proteins containing a CXXC motif with similarity to thioredoxin (TRX)-fold arsenic reductases, ArsC. Proteins containing a redox active CXXC motif like TRX and glutaredoxin (GRX)...; Region: ArsC_like; cd03036
519441002755	ArsC family; Region: ArsC; pfam03960
519441002756	putative ArsC-like catalytic residues; other site
519441002757	putative TRX-like catalytic residues [active]
519441002758	excinuclease ABC subunit B; Provisional; Region: PRK05298
519441002759	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
519441002760	ATP binding site [chemical binding]; other site
519441002761	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
519441002762	nucleotide binding region [chemical binding]; other site
519441002763	ATP-binding site [chemical binding]; other site
519441002764	Ultra-violet resistance protein B; Region: UvrB; pfam12344
519441002765	Uncharacterized BCR, COG1649; Region: DUF187; pfam02638
519441002766	Predicted O-methyltransferase [General function prediction only]; Region: COG4122
519441002767	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
519441002768	S-adenosylmethionine binding site [chemical binding]; other site
519441002769	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppF; COG1124
519441002770	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
519441002771	Walker A/P-loop; other site
519441002772	ATP binding site [chemical binding]; other site
519441002773	Q-loop/lid; other site
519441002774	ABC transporter signature motif; other site
519441002775	Walker B; other site
519441002776	D-loop; other site
519441002777	H-loop/switch region; other site
519441002778	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppF; COG1124
519441002779	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
519441002780	Walker A/P-loop; other site
519441002781	ATP binding site [chemical binding]; other site
519441002782	Q-loop/lid; other site
519441002783	ABC transporter signature motif; other site
519441002784	Walker B; other site
519441002785	D-loop; other site
519441002786	H-loop/switch region; other site
519441002787	nickel ABC transporter, permease subunit NikC; Region: nickel_nikC; TIGR02790
519441002788	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
519441002789	putative PBP binding loops; other site
519441002790	dimer interface [polypeptide binding]; other site
519441002791	ABC-ATPase subunit interface; other site
519441002792	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
519441002793	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cl00427
519441002794	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
519441002795	dimer interface [polypeptide binding]; other site
519441002796	conserved gate region; other site
519441002797	putative PBP binding loops; other site
519441002798	ABC-ATPase subunit interface; other site
519441002799	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
519441002800	DNA-binding site [nucleotide binding]; DNA binding site
519441002801	RNA-binding motif; other site
519441002802	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
519441002803	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
519441002804	RNA binding surface [nucleotide binding]; other site
519441002805	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
519441002806	active site
519441002807	rod shape-determining protein RodA; Region: rodA_shape; TIGR02210
519441002808	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
519441002809	Insulinase (Peptidase family M16); Region: Peptidase_M16; pfam00675
519441002810	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
519441002811	Colicin V production protein; Region: Colicin_V; pfam02674
519441002812	Alanine racemase [Cell envelope biogenesis, outer membrane]; Region: Alr; COG0787
519441002813	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Alanine Racemase; Region: PLPDE_III_AR; cd00430
519441002814	active site
519441002815	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
519441002816	dimer interface [polypeptide binding]; other site
519441002817	substrate binding site [chemical binding]; other site
519441002818	catalytic residues [active]
519441002819	cytidylate kinase; Provisional; Region: cmk; PRK00023
519441002820	Cytidine monophosphate kinase (CMPK) catalyzes the reversible phosphorylation of cytidine monophosphate (CMP) to produce cytidine diphosphate (CDP), using ATP as the preferred phosphoryl donor; Region: CMPK; cd02020
519441002821	CMP-binding site; other site
519441002822	The sites determining sugar specificity; other site
519441002823	Deinococcus radiodurans DR1281 and related proteins, metallophosphatase domain; Region: MPP_DR1281; cd07382
519441002824	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
519441002825	putative active site [active]
519441002826	metal binding site [ion binding]; metal-binding site
519441002827	homodimer binding site [polypeptide binding]; other site
519441002828	phosphodiesterase; Provisional; Region: PRK12704
519441002829	KH domain; Region: KH_1; pfam00013
519441002830	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
519441002831	Zn2+ binding site [ion binding]; other site
519441002832	Mg2+ binding site [ion binding]; other site
519441002833	Tetratricopeptide repeat; Region: TPR_12; pfam13424
519441002834	Xaa-Pro aminopeptidase [Amino acid transport and metabolism]; Region: PepP; COG0006
519441002835	Creatinase/Prolidase N-terminal domain; Region: Creatinase_N; pfam01321
519441002836	Similar to Prolidase and Aminopeptidase P. The members of this subfamily presumably catalyse hydrolysis of Xaa-Pro dipeptides and/or release of any N-terminal amino acid, including proline, that is linked with proline; Region: APP-like; cd01092
519441002837	active site
519441002838	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppC; COG1173
519441002839	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
519441002840	putative PBP binding loops; other site
519441002841	dimer interface [polypeptide binding]; other site
519441002842	ABC-ATPase subunit interface; other site
519441002843	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
519441002844	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
519441002845	dimer interface [polypeptide binding]; other site
519441002846	conserved gate region; other site
519441002847	putative PBP binding loops; other site
519441002848	ABC-ATPase subunit interface; other site
519441002849	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppF; COG1124
519441002850	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
519441002851	Walker A/P-loop; other site
519441002852	ATP binding site [chemical binding]; other site
519441002853	Q-loop/lid; other site
519441002854	ABC transporter signature motif; other site
519441002855	Walker B; other site
519441002856	D-loop; other site
519441002857	H-loop/switch region; other site
519441002858	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
519441002859	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppD; COG0444
519441002860	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
519441002861	Walker A/P-loop; other site
519441002862	ATP binding site [chemical binding]; other site
519441002863	Q-loop/lid; other site
519441002864	ABC transporter signature motif; other site
519441002865	Walker B; other site
519441002866	D-loop; other site
519441002867	H-loop/switch region; other site
519441002868	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
519441002869	ferric uptake regulator; Provisional; Region: fur; PRK09462
519441002870	Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators; Region: Fur_like; cd07153
519441002871	metal binding site 2 [ion binding]; metal-binding site
519441002872	putative DNA binding helix; other site
519441002873	metal binding site 1 [ion binding]; metal-binding site
519441002874	dimer interface [polypeptide binding]; other site
519441002875	structural Zn2+ binding site [ion binding]; other site
519441002876	Asparagine synthetase (aspartate-ammonia ligase) (AsnA) catalyses the conversion of L-aspartate to L-asparagine in the presence of ATP and ammonia.  AsnA is a homodimeric enzyme which is structurally similiar to the catalytic core domain of class II...; Region: AsnA; cd00645
519441002877	dimer interface [polypeptide binding]; other site
519441002878	active site
519441002879	NAD-dependent DNA ligase LigA; Validated; Region: ligA; PRK07956
519441002880	NAD+ dependent DNA ligase adenylation domain. DNA ligases catalyze the crucial step of joining the breaks in duplex DNA during DNA replication, repair and recombination, utilizing either ATP or NAD(+) as a cofactor, but using the same basic reaction...; Region: LIGANc; cd00114
519441002881	nucleotide binding pocket [chemical binding]; other site
519441002882	K-X-D-G motif; other site
519441002883	catalytic site [active]
519441002884	NAD-dependent DNA ligase OB-fold domain; Region: DNA_ligase_OB; pfam03120
519441002885	NAD-dependent DNA ligase C4 zinc finger domain; Region: DNA_ligase_ZBD; pfam03119
519441002886	Breast Cancer Suppressor Protein (BRCA1), carboxy-terminal domain. The BRCT domain is found within many DNA damage repair and cell cycle checkpoint proteins. The unique diversity of this domain superfamily allows BRCT modules to interact forming homo...; Region: BRCT; cd00027
519441002887	Dimer interface [polypeptide binding]; other site
519441002888	BRCT sequence motif; other site
519441002889	inosine 5'-monophosphate dehydrogenase; Reviewed; Region: PRK05567
519441002890	TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl17186
519441002891	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in the inosine 5' monophosphate dehydrogenase (IMPDH) protein.  IMPDH is an essential enzyme that catalyzes the first step unique to GTP synthesis, playing a...; Region: CBS_pair_IMPDH; cd04601
519441002892	IMPDH: The catalytic domain of the inosine monophosphate dehydrogenase. IMPDH catalyzes the NAD-dependent oxidation of inosine 5'-monophosphate (IMP) to xanthosine 5' monophosphate (XMP). It is a rate-limiting step in the de novo synthesis of...; Region: IMPDH; cd00381
519441002893	active site
519441002894	Family 1 of Uracil-DNA glycosylase (UDG) enzymes; Region: UDG_F1; cd10027
519441002895	ligand binding site [chemical binding]; other site
519441002896	active site
519441002897	UGI interface [polypeptide binding]; other site
519441002898	catalytic site [active]
519441002899	mRNA degradation ribonucleases J1/J2 (metallo-beta-lactamase superfamily) [Translation, ribosomal structure and biogenesis; Replication, recombination and repair]; Region: COG0595
519441002900	Metallo-beta-lactamase superfamily; Region: Lactamase_B; pfam00753
519441002901	RNA-metabolising metallo-beta-lactamase; Region: RMMBL; pfam07521
519441002902	tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA; Validated; Region: PRK05192
519441002903	NAD(FAD)-utilizing enzyme possibly involved in translation [Translation, ribosomal structure and biogenesis]; Region: Gid; COG1206
519441002904	tRNA (uracil-5-)-methyltransferase Gid; Reviewed; Region: PRK05335
519441002905	GidA associated domain 3; Region: GIDA_assoc_3; pfam13932
519441002906	K+ transport systems, NAD-binding component [Inorganic ion transport and metabolism]; Region: TrkA; COG0569
519441002907	TrkA-N domain; Region: TrkA_N; pfam02254
519441002908	TrkA-C domain; Region: TrkA_C; pfam02080
519441002909	potassium uptake protein, TrkH family; Region: 2a38; TIGR00933
519441002910	Trk-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: TrkG; COG0168
519441002911	SurA N-terminal domain; Region: SurA_N_3; cl07813
519441002912	PPIC-type PPIASE domain; Region: Rotamase; pfam00639
519441002913	Protein of unknown function (DUF328); Region: DUF328; cl01143
519441002914	16S RNA G1207 methylase RsmC [Translation, ribosomal structure and biogenesis]; Region: RsmC; COG2813
519441002915	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
519441002916	S-adenosylmethionine binding site [chemical binding]; other site
519441002917	Acetyltransferases [General function prediction only]; Region: RimI; COG0456
519441002918	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
519441002919	Coenzyme A binding pocket [chemical binding]; other site
519441002920	Glutamine Amidotransferase (GATase_I) involved in pyridoxine biosynthesis; Region: GATase1_PB; cd01749
519441002921	imidazole glycerol phosphate synthase, glutamine amidotransferase subunit; Region: IMP_synth_hisH; TIGR01855
519441002922	predicted active site [active]
519441002923	catalytic triad [active]
519441002924	pyridoxal 5'-phosphate synthase, synthase subunit Pdx1; Region: TIGR00343
519441002925	PdxS is a subunit of the pyridoxal 5'-phosphate (PLP) synthase, an important enzyme in deoxyxylulose 5-phosphate (DXP)-independent pathway for de novo biosynthesis of PLP,  present in some eubacteria, in archaea, fungi, plants, plasmodia, and some...; Region: pdxS; cd04727
519441002926	active site
519441002927	multimer interface [polypeptide binding]; other site
519441002928	Signal peptide peptidase A (SppA) 67K type, a serine protease, has catalytic Ser-Lys dyad; Region: S49_SppA_67K_type; cd07018
519441002929	oligomer interface [polypeptide binding]; other site
519441002930	tandem repeat interface [polypeptide binding]; other site
519441002931	active site residues [active]
519441002932	signal peptide peptidase SppA, 36K type; Region: SppA_dom; TIGR00706
519441002933	Signal peptide peptidase A (SppA), a serine protease, has catalytic Ser-Lys dyad; Region: S49_Sppa_N_C; cd07023
519441002934	tandem repeat interface [polypeptide binding]; other site
519441002935	oligomer interface [polypeptide binding]; other site
519441002936	active site residues [active]
519441002937	ATP-dependent DNA helicase PcrA; Region: pcrA; TIGR01073
519441002938	Part of AAA domain; Region: AAA_19; pfam13245
519441002939	Family description; Region: UvrD_C_2; pfam13538
519441002940	Domain of unknown function (DUF4300); Region: DUF4300; pfam14133
519441002941	enolase; Provisional; Region: eno; PRK00077
519441002942	Enolase: Enolases are homodimeric enzymes that catalyse the reversible dehydration of 2-phospho-D-glycerate to phosphoenolpyruvate as part of the glycolytic and gluconeogenesis pathways. The reaction is facilitated by the presence of metal ions; Region: enolase; cd03313
519441002943	dimer interface [polypeptide binding]; other site
519441002944	metal binding site [ion binding]; metal-binding site
519441002945	substrate binding pocket [chemical binding]; other site
519441002946	Uncharacterized conserved protein [Function unknown]; Region: COG3589
519441002947	Bacterial protein of unknown function (DUF871); Region: DUF871; pfam05913
519441002948	S-formylglutathione hydrolase; Region: PLN02442
519441002949	Putative esterase; Region: Esterase; pfam00756
519441002950	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
519441002951	PTS system N-acetylmuramic acid transporter subunits EIIBC; Reviewed; Region: murP; PRK09586
519441002952	active site turn [active]
519441002953	phosphorylation site [posttranslational modification]
519441002954	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
519441002955	Transcriptional regulators [Transcription]; Region: RpiR; COG1737
519441002956	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
519441002957	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
519441002958	putative active site [active]
519441002959	N-acetylmuramic acid-6-phosphate etherase; Reviewed; Region: murQ; PRK05441
519441002960	N-acetylmuramic acid 6-phosphate etherase. Members of this family contain the SIS (Sugar ISomerase) domain. The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. The bacterial cell wall sugar N-acetylmuramic acid...; Region: SIS_Etherase; cd05007
519441002961	putative active site [active]
519441002962	ATP-binding cassette domain of the carbohydrate and solute transporters-like; Region: ABC_Carb_Solutes_like; cd03259
519441002963	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
519441002964	Walker A/P-loop; other site
519441002965	ATP binding site [chemical binding]; other site
519441002966	Q-loop/lid; other site
519441002967	ABC transporter signature motif; other site
519441002968	Walker B; other site
519441002969	D-loop; other site
519441002970	H-loop/switch region; other site
519441002971	ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism]; Region: ThiP; COG1178
519441002972	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
519441002973	dimer interface [polypeptide binding]; other site
519441002974	conserved gate region; other site
519441002975	putative PBP binding loops; other site
519441002976	ABC-ATPase subunit interface; other site
519441002977	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
519441002978	dimer interface [polypeptide binding]; other site
519441002979	conserved gate region; other site
519441002980	putative PBP binding loops; other site
519441002981	ABC-ATPase subunit interface; other site
519441002982	ABC-type Fe3+ transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: AfuA; COG1840
519441002983	Bacterial extracellular solute-binding protein; Region: SBP_bac_8; pfam13416
519441002984	uracil transporter; Provisional; Region: PRK10720
519441002985	DHH family; Region: DHH; pfam01368
519441002986	Predicted phosphohydrolase (DHH superfamily) [General function prediction only]; Region: COG2404
519441002987	Holliday junction resolvases (HJRs) are endonucleases that specifically resolve Holliday junction DNA intermediates during homologous recombination. HJR's occur in archaea, bacteria, and in the mitochondria of certain fungi, however this CD...; Region: RuvC_resolvase; cd00529
519441002988	active site
519441002989	putative DNA-binding cleft [nucleotide binding]; other site
519441002990	dimer interface [polypeptide binding]; other site
519441002991	L-lactate dehydrogenase; Reviewed; Region: ldh; PRK00066
519441002992	A subgroup of L-lactate dehydrogenases; Region: LDH_2; cd05292
519441002993	NAD binding site [chemical binding]; other site
519441002994	dimer interface [polypeptide binding]; other site
519441002995	substrate binding site [chemical binding]; other site
519441002996	tetramer (dimer of dimers) interface [polypeptide binding]; other site
519441002997	TlpA-like family; composed of  TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a...; Region: TlpA_like_family; cd02966
519441002998	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
519441002999	catalytic residues [active]
519441003000	putative PEP-CTERM system TPR-repeat lipoprotein; Region: PEP_TPR_lipo; TIGR02917
519441003001	methionyl-tRNA synthetase; Reviewed; Region: PRK12267
519441003002	catalytic core domain of methioninyl-tRNA synthetases; Region: MetRS_core; cd00814
519441003003	active site
519441003004	HIGH motif; other site
519441003005	KMSKS motif; other site
519441003006	Anticodon-binding domain of methionyl tRNA synthetases; Region: Anticodon_Ia_Met; cd07957
519441003007	tRNA binding surface [nucleotide binding]; other site
519441003008	anticodon binding site; other site
519441003009	The tRNA binding domain is also known as the Myf domain in literature. This domain is found in a diverse collection of tRNA binding proteins, including prokaryotic phenylalanyl tRNA synthetases (PheRS), methionyl-tRNA synthetases (MetRS), human...; Region: tRNA_bindingDomain; cl00320
519441003010	putative tRNA-binding site [nucleotide binding]; other site
519441003011	Dihydrofolate reductase [Coenzyme metabolism]; Region: FolA; COG0262
519441003012	Dihydrofolate reductase (DHFR). Reduces 7,8-dihydrofolate to 5,6,7,8-tetrahydrofolate with NADPH as a cofactor. This is an essential step in the biosynthesis of deoxythymidine phosphate since 5,6,7,8-tetrahydrofolate is required to regenerate 5; Region: DHFR; cd00209
519441003013	folate binding site [chemical binding]; other site
519441003014	NADP+ binding site [chemical binding]; other site
519441003015	Predicted rRNA methylase (SpoU class) [Translation, ribosomal structure and biogenesis]; Region: CspR; COG0219
519441003016	RseP-like Site-2 proteases (S2P), zinc metalloproteases (MEROPS family M50A), cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. In Escherichia coli, the S2P homolog...; Region: S2P-M50_PDZ_RseP-like; cd06163
519441003017	Peptidase family M50; Region: Peptidase_M50; pfam02163
519441003018	active site
519441003019	putative substrate binding region [chemical binding]; other site
519441003020	Predicted transcriptional regulators [Transcription]; Region: COG1378
519441003021	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
519441003022	putative DNA binding site [nucleotide binding]; other site
519441003023	putative Zn2+ binding site [ion binding]; other site
519441003024	deoxyguanosinetriphosphate triphosphohydrolase-like protein; Provisional; Region: PRK01096
519441003025	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
519441003026	Zn2+ binding site [ion binding]; other site
519441003027	Mg2+ binding site [ion binding]; other site
519441003028	Phosphohydrolase-associated domain; Region: HD_assoc; pfam13286
519441003029	Na+-driven multidrug efflux pump [Defense mechanisms]; Region: NorM; COG0534
519441003030	Multidrug and toxic compound extrusion family and similar proteins; Region: MATE_like; cl09326
519441003031	Mycoplasma pulmonis MnuA nuclease-like; Region: MnuA_DNase1-like; cd10283
519441003032	putative active site [active]
519441003033	putative catalytic site [active]
519441003034	putative Mg binding site IVb [ion binding]; other site
519441003035	putative phosphate binding site [ion binding]; other site
519441003036	putative DNA binding site [nucleotide binding]; other site
519441003037	putative Mg binding site IVa [ion binding]; other site
519441003038	elongation factor P; Validated; Region: PRK00529
519441003039	Elongation factor P (EF-P) KOW-like domain; Region: EFP_N; pfam08207
519441003040	S1_EF-P_repeat_1: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_1; cd04470
519441003041	RNA binding site [nucleotide binding]; other site
519441003042	S1_EF-P_repeat_2: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_2; cd05794
519441003043	RNA binding site [nucleotide binding]; other site
519441003044	aspartate-semialdehyde dehydrogenase; Provisional; Region: PRK14874
519441003045	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
519441003046	diaminopimelate epimerase; Provisional; Region: dapF; PRK00450
519441003047	Diaminopimelate epimerase; Region: DAP_epimerase; pfam01678
519441003048	Diaminopimelate epimerase; Region: DAP_epimerase; pfam01678
519441003049	Dihydrodipicolinate synthase/N-acetylneuraminate lyase [Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: DapA; COG0329
519441003050	Dihydrodipicolinate synthase (DHDPS); Region: DHDPS; cd00950
519441003051	dimer interface [polypeptide binding]; other site
519441003052	active site
519441003053	catalytic residue [active]
519441003054	TM1410 hypothetical-related protein; Region: DUF297; cl00997
519441003055	aspartate kinase; Reviewed; Region: PRK06635
519441003056	AAK_AK-DapG-like: Amino Acid Kinase Superfamily (AAK), AK-DapG-like; this CD includes the N-terminal catalytic aspartokinase (AK) domain of the diaminopimelate-sensitive aspartokinase isoenzyme AKI (DapG), a monofunctional enzymes found in Bacilli; Region: AAK_AK-DapG-like; cd04246
519441003057	putative catalytic residues [active]
519441003058	putative nucleotide binding site [chemical binding]; other site
519441003059	putative aspartate binding site [chemical binding]; other site
519441003060	ACT domains of the lysine-sensitive aspartokinase isoenzyme AKII and related proteins; Region: ACT_AK-LysC-DapG-like_1; cd04891
519441003061	ACT domains are commonly involved in specifically binding an amino acid or other small ligand leading to regulation of the enzyme; Region: ACT; cl09141
519441003062	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2849
519441003063	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
519441003064	CoA-disulfide reductase; Region: CoA_CoA_reduc; TIGR03385
519441003065	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
519441003066	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
519441003067	dihydrodipicolinate reductase; Provisional; Region: PRK00048
519441003068	Dihydrodipicolinate reductase, N-terminus; Region: DapB_N; pfam01113
519441003069	Dihydrodipicolinate reductase, C-terminus; Region: DapB_C; pfam05173
519441003070	Short-chain dehydrogenases of various substrate specificities [General function prediction only]; Region: DltE; COG0300
519441003071	classical (c) SDRs; Region: SDR_c; cd05233
519441003072	NAD(P) binding site [chemical binding]; other site
519441003073	active site
519441003074	Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Bacillus subtilis yoeA; Region: MATE_yoeA_like; cd13138
519441003075	Na+-driven multidrug efflux pump [Defense mechanisms]; Region: NorM; COG0534
519441003076	anaerobic sulfatase-maturating enzyme; Region: sulfatase_rSAM; TIGR03942
519441003077	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
519441003078	FeS/SAM binding site; other site
519441003079	radical SAM additional 4Fe4S-binding SPASM domain; Region: rSAM_more_4Fe4S; TIGR04085
519441003080	Elongation factor G (EF-G) family; Region: EF-G_bact; cd04170
519441003081	elongation factor G; Reviewed; Region: PRK12740
519441003082	G1 box; other site
519441003083	putative GEF interaction site [polypeptide binding]; other site
519441003084	GTP/Mg2+ binding site [chemical binding]; other site
519441003085	Switch I region; other site
519441003086	G2 box; other site
519441003087	G3 box; other site
519441003088	Switch II region; other site
519441003089	G4 box; other site
519441003090	G5 box; other site
519441003091	EFG_mtEFG_II: this subfamily represents the domain II of elongation factor G (EF-G) in bacteria and, the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2)_like proteins found in eukaryotes. During the process of peptide synthesis...; Region: EFG_mtEFG_II; cd04088
519441003092	Elongation Factor G-like domain IV. This family includes the translational elongation factor termed EF-2 (for Archaea and Eukarya) and EF-G (for Bacteria), ribosomal protection proteins that mediate tetracycline resistance and, an evolutionarily...; Region: EFG_like_IV; cl02789
519441003093	EFG_mtEFG_C: domains similar to the C-terminal domain of the bacterial translational elongation factor (EF) EF-G.  Included in this group is the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2) proteins. Eukaryotic cells harbor 2...; Region: EFG_mtEFG_C; cd03713
519441003094	Transposase zinc-binding domain; Region: Zn_Tnp_IS91; pfam14319
519441003095	Putative transposase; Region: Y2_Tnp; pfam04986
519441003096	NlpC/P60 family; Region: NLPC_P60; pfam00877
519441003097	D-Tyrosyl-tRNAtyr deacylases; a class of tRNA-dependent hydrolases which are capable of hydrolyzing the ester bond of D-Tyrosyl-tRNA reducing the level of cellular D-Tyrosine while recycling the peptidyl-tRNA; found in bacteria and in eukaryotes but not...; Region: Dtyr_deacylase; cd00563
519441003098	putative active site [active]
519441003099	dimerization interface [polypeptide binding]; other site
519441003100	putative tRNAtyr binding site [nucleotide binding]; other site
519441003101	Sulfite exporter TauE/SafE; Region: TauE; pfam01925
519441003102	Uncharacterized FAD-dependent dehydrogenases [General function prediction only]; Region: COG2509
519441003103	flavoprotein, HI0933 family; Region: TIGR00275
519441003104	Abi-like protein; Region: Abi_2; cl01988
519441003105	Uncharacterized BCR, COG1636; Region: DUF208; pfam02677
519441003106	Tetrahydrodipicolinate succinyltransferase N-terminal; Region: DapH_N; pfam08503
519441003107	2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase; Region: DapD_Ac; TIGR03532
519441003108	2,3,4,5-tetrahydropyridine-2,6-dicarboxylate (THDP) N-succinyltransferase (also called THP succinyltransferase): THDP N-succinyltransferase catalyzes the conversion of tetrahydrodipicolinate and succinyl-CoA to N-succinyltetrahydrodipicolinate and CoA; Region: LbH_THP_succinylT; cd03350
519441003109	active site
519441003110	trimer interface [polypeptide binding]; other site
519441003111	substrate binding site [chemical binding]; other site
519441003112	CoA binding site [chemical binding]; other site
519441003113	Peptidase family M3B Oligopeptidase F (PepF); Region: M3B_PepF_1; cd09606
519441003114	oligoendopeptidase, M3 family; Region: M3_not_pepF; TIGR02289
519441003115	active site
519441003116	Zn binding site [ion binding]; other site
519441003117	mitochondrial ATP synthase delta subunit; Region: F1-ATPase_delta; cd12152
519441003118	gamma subunit interface [polypeptide binding]; other site
519441003119	LBP interface [polypeptide binding]; other site
519441003120	F0F1 ATP synthase subunit beta; Validated; Region: PRK09280
519441003121	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
519441003122	F1 ATP synthase beta subunit, nucleotide-binding domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a...; Region: F1-ATPase_beta; cd01133
519441003123	alpha subunit interaction interface [polypeptide binding]; other site
519441003124	Walker A motif; other site
519441003125	ATP binding site [chemical binding]; other site
519441003126	Walker B motif; other site
519441003127	inhibitor binding site; inhibition site
519441003128	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
519441003129	mitochondrial ATP synthase gamma subunit; Region: F1-ATPase_gamma; cd12151
519441003130	core domain interface [polypeptide binding]; other site
519441003131	delta subunit interface [polypeptide binding]; other site
519441003132	epsilon subunit interface [polypeptide binding]; other site
519441003133	F0F1 ATP synthase subunit alpha; Validated; Region: PRK09281
519441003134	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
519441003135	F1 ATP synthase alpha, central domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a proton gradient to...; Region: F1_ATPase_alpha; cd01132
519441003136	beta subunit interaction interface [polypeptide binding]; other site
519441003137	Walker A motif; other site
519441003138	ATP binding site [chemical binding]; other site
519441003139	Walker B motif; other site
519441003140	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
519441003141	F0F1 ATP synthase subunit delta; Validated; Region: PRK05758
519441003142	ATP synthase delta (OSCP) subunit; Region: OSCP; pfam00213
519441003143	F0F1-type ATP synthase, subunit b [Energy production and conversion]; Region: AtpF; COG0711
519441003144	F0F1 ATP synthase subunit B; Validated; Region: PRK05759
519441003145	ATP synthase subunit C; Region: ATP-synt_C; cl00466
519441003146	F0F1 ATP synthase subunit A; Validated; Region: PRK05815
519441003147	Uncharacterized protein conserved in bacteria (DUF2147); Region: DUF2147; pfam09917
519441003148	lysyl-tRNA synthetase; Reviewed; Region: lysS; PRK00484
519441003149	LysRS_N: N-terminal, anticodon recognition domain of lysyl-tRNA synthetases (LysRS). These enzymes are homodimeric class 2b aminoacyl-tRNA synthetases (aaRSs). This domain is a beta-barrel domain (OB fold) involved in binding the tRNA anticodon stem-loop; Region: LysRS_N; cd04322
519441003150	dimer interface [polypeptide binding]; other site
519441003151	putative anticodon binding site; other site
519441003152	Lys_tRNA synthetase (LysRS) class II core domain. Class II LysRS is a dimer which attaches a lysine to the 3' OH group of ribose of the appropriate tRNA. Its assignment to class II aaRS is based upon its structure and the presence of three...; Region: LysRS_core; cd00775
519441003153	motif 1; other site
519441003154	active site
519441003155	motif 2; other site
519441003156	motif 3; other site
519441003157	rRNA large subunit methyltransferase; Provisional; Region: PRK00103
519441003158	DNA methylase; Region: N6_N4_Mtase; pfam01555
519441003159	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
519441003160	S-adenosylmethionine binding site [chemical binding]; other site
519441003161	DNA methylase; Region: N6_N4_Mtase; cl17433
519441003162	DNA mismatch repair protein; Reviewed; Region: mutL; PRK00095
519441003163	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
519441003164	Mg2+ binding site [ion binding]; other site
519441003165	G-X-G motif; other site
519441003166	MutL_Trans: transducer domain, having a ribosomal S5 domain 2-like fold, conserved in the C-terminal domain of DNA mismatch repair (MutL/MLH1/PMS2) family. This transducer domain is homologous to the second domain of the DNA gyrase B subunit, which is...; Region: MutL_Trans; cd00782
519441003167	ATP binding site [chemical binding]; other site
519441003168	MutL C terminal dimerisation domain; Region: MutL_C; pfam08676
519441003169	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
519441003170	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
519441003171	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
519441003172	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
519441003173	dimer interface [polypeptide binding]; other site
519441003174	conserved gate region; other site
519441003175	putative PBP binding loops; other site
519441003176	ABC-ATPase subunit interface; other site
519441003177	ABC-type polysaccharide transport system, permease component [Carbohydrate transport and metabolism]; Region: LplB; COG4209
519441003178	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
519441003179	dimer interface [polypeptide binding]; other site
519441003180	ABC-ATPase subunit interface; other site
519441003181	putative PBP binding loops; other site
519441003182	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
519441003183	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
519441003184	Dihydrodipicolinate synthase/N-acetylneuraminate lyase [Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: DapA; COG0329
519441003185	Class I aldolases; Region: Aldolase_Class_I; cl17187
519441003186	catalytic residue [active]
519441003187	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
519441003188	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
519441003189	nucleotide binding site [chemical binding]; other site
519441003190	N-acetylmannosamine-6-phosphate epimerase (NanE) converts N-acetylmannosamine-6-phosphate to N-acetylglucosamine-6-phosphate. This reaction is part of the pathway that allows the usage of sialic acid as a carbohydrate source. Sialic acids are a family of...; Region: NanE; cd04729
519441003191	N-acetylmannosamine-6-phosphate 2-epimerase; Provisional; Region: PRK01130
519441003192	putative active site cavity [active]
519441003193	Transcriptional regulators [Transcription]; Region: RpiR; COG1737
519441003194	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
519441003195	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
519441003196	putative active site [active]
519441003197	cyclically-permuted mutarotase family protein; Region: mutarot_permut; TIGR03548
519441003198	Galactose oxidase, central domain; Region: Kelch_3; pfam13415
519441003199	bifunctional acetaldehyde-CoA/alcohol dehydrogenase; Provisional; Region: PRK13805
519441003200	Coenzyme A acylating aldehyde dehydrogenase (ACDH), ALDH family 20-like; Region: ALDH_F20_ACDH; cd07122
519441003201	putative catalytic cysteine [active]
519441003202	C-terminal alcohol dehydrogenase domain of the acetaldehyde dehydrogenase-alcohol dehydrogenase bifunctional two-domain protein (AAD); Region: AAD_C; cd08178
519441003203	putative active site [active]
519441003204	metal binding site [ion binding]; metal-binding site
519441003205	YjgF, YER057c, and UK114 belong to a large family of proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no...; Region: YjgF_YER057c_UK114_family; cd00448
519441003206	homotrimer interaction site [polypeptide binding]; other site
519441003207	putative active site [active]
519441003208	elongation factor Tu; Reviewed; Region: PRK00049
519441003209	Elongation Factor Tu (EF-Tu) GTP-binding proteins; Region: EF_Tu; cd01884
519441003210	G1 box; other site
519441003211	GEF interaction site [polypeptide binding]; other site
519441003212	GTP/Mg2+ binding site [chemical binding]; other site
519441003213	Switch I region; other site
519441003214	G2 box; other site
519441003215	G3 box; other site
519441003216	Switch II region; other site
519441003217	G4 box; other site
519441003218	G5 box; other site
519441003219	EFTU_II: Elongation factor Tu domain II. Elongation factors Tu (EF-Tu) are three-domain GTPases with an essential function in the elongation phase of mRNA translation. The GTPase center of EF-Tu is in the N-terminal domain (domain I), also known as the...; Region: EFTU_II; cd03697
519441003220	Domain III of elongation factor (EF) Tu. Ef-Tu consists of three structural domains, designated I, II and III. Domain III adopts a beta barrel structure. Domain III is involved in binding to both charged tRNA and binding to elongation factor Ts (EF-Ts); Region: EFTU_III; cd03707
519441003221	Antibiotic Binding Site [chemical binding]; other site
519441003222	alpha/beta hydrolase fold; Region: Abhydrolase_3; pfam07859
519441003223	Protein of unknown function (DUF2424); Region: DUF2424; pfam10340
519441003224	peptidase T; Region: peptidase-T; TIGR01882
519441003225	M20 Peptidase T specifically cleaves tripeptides; Region: M20_peptT; cd03892
519441003226	metal binding site [ion binding]; metal-binding site
519441003227	dimer interface [polypeptide binding]; other site
519441003228	formate acetyltransferase 1; Region: pyr_form_ly_1; TIGR01255
519441003229	Pyruvate formate lyase 1; Region: PFL1; cd01678
519441003230	coenzyme A binding site [chemical binding]; other site
519441003231	active site
519441003232	catalytic residues [active]
519441003233	glycine loop; other site
519441003234	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
519441003235	catalytic core [active]
519441003236	CRISPR/Cas system-associated protein Cas2; Region: Cas2_I_II_III; cl11442
519441003237	CRISPR/Cas system-associated protein Cas1; Region: Cas1_I-II-III; cl00656
519441003238	HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and...; Region: HNHc; cl00083
519441003239	CRISPR-associated protein Cas9/Csn1, subtype II/NMEMI; Region: cas_Csn1; TIGR01865
519441003240	Immunoglobulin A1 protease; Region: Peptidase_S6; pfam02395
519441003241	Immunoglobulin A1 protease; Region: Peptidase_S6; pfam02395
519441003242	aspartyl-tRNA synthetase; Validated; Region: aspS; PRK00476
519441003243	EcAspRS_like_N: N-terminal, anticodon recognition domain of the type found in Escherichia coli aspartyl-tRNA synthetase (AspRS), the human mitochondrial (mt) AspRS-2, the discriminating (D) Thermus thermophilus AspRS-1, and the nondiscriminating (ND)...; Region: EcAspRS_like_N; cd04317
519441003244	dimer interface [polypeptide binding]; other site
519441003245	anticodon binding site; other site
519441003246	Asp tRNA synthetase (aspRS) class II core domain. Class II assignment is based upon its structure and the presence of three characteristic sequence motifs. AspRS is a homodimer, which attaches a specific amino acid to the 3' OH group of ribose of...; Region: AspRS_core; cd00777
519441003247	homodimer interface [polypeptide binding]; other site
519441003248	motif 1; other site
519441003249	active site
519441003250	motif 2; other site
519441003251	GAD domain; Region: GAD; pfam02938
519441003252	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
519441003253	active site
519441003254	motif 3; other site
519441003255	histidyl-tRNA synthetase; Reviewed; Region: hisS; PRK00037
519441003256	Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core domain. HisRS is a homodimer. It is responsible for the attachment of histidine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for...; Region: HisRS-like_core; cd00773
519441003257	dimer interface [polypeptide binding]; other site
519441003258	motif 1; other site
519441003259	active site
519441003260	motif 2; other site
519441003261	motif 3; other site
519441003262	HisRS Histidyl-anticodon binding domain. HisRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: HisRS_anticodon; cd00859
519441003263	anticodon binding site; other site
519441003264	Thymidylate kinase [Nucleotide transport and metabolism]; Region: Tmk; COG0125
519441003265	Thymidine monophosphate kinase (TMPK), also known as thymidylate kinase, catalyzes the phosphorylation of thymidine monophosphate (TMP) to thymidine diphosphate (TDP) utilizing ATP as its preferred phophoryl donor. TMPK represents the rate-limiting step...; Region: TMPK; cd01672
519441003266	TMP-binding site; other site
519441003267	ATP-binding site [chemical binding]; other site
519441003268	NifU homolog involved in Fe-S cluster formation [Energy production and conversion]; Region: IscU; COG0822
519441003269	Iron-sulfur cluster scaffold-like proteins; Region: IscU_like; cd06664
519441003270	trimerization site [polypeptide binding]; other site
519441003271	active site
519441003272	DNA modification methylase [DNA replication, recombination, and repair]; Region: COG0863
519441003273	DNA methylase; Region: N6_N4_Mtase; pfam01555
519441003274	ApaLI-like restriction endonuclease; Region: RE_ApaLI; pfam09499
519441003275	YhcR_OBF_like: A subfamily of OB-fold domains similar to the OB folds of Bacillus subtilis YhcR. YhcR is a sugar-nonspecific nuclease, which is active in the presence of Ca2+ and Mn2+. It cleaves RNA endonucleolytically, producing 3'-monophosphate...; Region: YhcR_OBF_like; cd04486
519441003276	generic binding surface II; other site
519441003277	generic binding surface I; other site
519441003278	Exonuclease-Endonuclease-Phosphatase (EEP) domain superfamily; Region: EEP; cl00490
519441003279	putative catalytic site [active]
519441003280	putative metal binding site [ion binding]; other site
519441003281	putative phosphate binding site [ion binding]; other site
519441003282	GTP-binding protein Der; Reviewed; Region: PRK00093
519441003283	EngA1 GTPase contains the first domain of EngA; Region: EngA1; cd01894
519441003284	G1 box; other site
519441003285	GTP/Mg2+ binding site [chemical binding]; other site
519441003286	Switch I region; other site
519441003287	G2 box; other site
519441003288	Switch II region; other site
519441003289	G3 box; other site
519441003290	G4 box; other site
519441003291	G5 box; other site
519441003292	EngA2 GTPase contains the second domain of EngA; Region: EngA2; cd01895
519441003293	G1 box; other site
519441003294	GTP/Mg2+ binding site [chemical binding]; other site
519441003295	Switch I region; other site
519441003296	G2 box; other site
519441003297	G3 box; other site
519441003298	Switch II region; other site
519441003299	G4 box; other site
519441003300	G5 box; other site
519441003301	Uncharacterized conserved protein [Function unknown]; Region: COG1739
519441003302	Uncharacterized protein family UPF0029; Region: UPF0029; pfam01205
519441003303	Domain of unknown function (DUF1949); Region: DUF1949; pfam09186
519441003304	Uncharacterized homologs of Site-2 protease (S2P), zinc metalloproteases (MEROPS family M50) which cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. Members of the...; Region: S2P-M50_like_1; cd06158
519441003305	active site
519441003306	putative substrate binding region [chemical binding]; other site
519441003307	D-alanine--D-alanine ligase; Reviewed; Region: ddl; PRK01372
519441003308	D-ala D-ala ligase N-terminus; Region: Dala_Dala_lig_N; pfam01820
519441003309	ATP-grasp domain; Region: ATP-grasp_4; cl17255
519441003310	Sulphate Transporter and Anti-Sigma factor antagonist) domain of anti-anti-sigma factors, key regulators of anti-sigma factors by phosphorylation; Region: STAS_anti-anti-sigma_factors; cd07043
519441003311	anti sigma factor interaction site; other site
519441003312	regulatory phosphorylation site [posttranslational modification]; other site
519441003313	Hsp33-like chaperonin; Reviewed; Region: hslO; PRK00114
519441003314	Heat shock protein 33 (Hsp33):  Cytosolic protein that acts as a molecular chaperone under oxidative conditions.  In normal (reducing) cytosolic conditions, four conserved Cys residues are coordinated by a Zn ion. Under oxidative stress (such as heat...; Region: Hsp33; cd00498
519441003315	dimerization interface [polypeptide binding]; other site
519441003316	domain crossover interface; other site
519441003317	redox-dependent activation switch; other site
519441003318	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
519441003319	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
519441003320	Surface antigen; Region: Bac_surface_Ag; pfam01103
519441003321	Surface antigen; Region: Bac_surface_Ag; pfam01103
519441003322	AsmA-like C-terminal region; Region: AsmA_2; pfam13502
519441003323	Family of unknown function (DUF490); Region: DUF490; pfam04357
519441003324	Family of unknown function (DUF490); Region: DUF490; pfam04357
519441003325	Predicted S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division [Cell envelope biogenesis, outer membrane]; Region: GidB; COG0357
519441003326	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
519441003327	S-adenosylmethionine binding site [chemical binding]; other site
519441003328	penicillin-binding protein 2; Region: pbp2_mrdA; TIGR03423
519441003329	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
519441003330	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
519441003331	iojap-like ribosome-associated protein; Region: iojap_ybeB; TIGR00090
519441003332	RNA methyltransferase, RsmE family; Region: TIGR00046
519441003333	16S ribosomal RNA methyltransferase RsmE; Provisional; Region: PRK11713
519441003334	Holliday junction DNA helicase RuvB; Reviewed; Region: ruvB; PRK00080
519441003335	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
519441003336	Walker A motif; other site
519441003337	ATP binding site [chemical binding]; other site
519441003338	Walker B motif; other site
519441003339	arginine finger; other site
519441003340	Holliday junction DNA helicase ruvB C-terminus; Region: RuvB_C; pfam05491
519441003341	glycyl-tRNA synthetase subunit beta; Validated; Region: glyS; PRK01233
519441003342	Class II Glycyl-tRNA synthetase (GlyRS) alpha subunit core catalytic domain. GlyRS functions as a homodimer in eukaryotes, archaea and some bacteria and as a heterotetramer in the remainder of prokaryotes and in arabidopsis. It is responsible for the...; Region: GlyRS_alpha_core; cd00733
519441003343	dimer interface [polypeptide binding]; other site
519441003344	motif 1; other site
519441003345	active site
519441003346	motif 2; other site
519441003347	motif 3; other site
519441003348	Signal peptidase (SPase) II; Region: Peptidase_A8; pfam01252
519441003349	isoleucyl-tRNA synthetase; Reviewed; Region: ileS; PRK05743
519441003350	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
519441003351	active site
519441003352	HIGH motif; other site
519441003353	nucleotide binding site [chemical binding]; other site
519441003354	catalytic core domain of isoleucyl-tRNA synthetases; Region: IleRS_core; cd00818
519441003355	active site
519441003356	KMSKS motif; other site
519441003357	Anticodon-binding domain of bacterial and eukaryotic mitochondrial isoleucyl tRNA synthetases; Region: Anticodon_Ia_Ile_BEm; cd07960
519441003358	tRNA binding surface [nucleotide binding]; other site
519441003359	anticodon binding site; other site
519441003360	Zinc finger found in FPG and IleRS; Region: zf-FPG_IleRS; pfam06827
519441003361	Transcriptional accessory protein [Transcription]; Region: Tex; COG2183
519441003362	Tex-like protein N-terminal domain; Region: Tex_N; pfam09371
519441003363	Likely ribonuclease with RNase H fold; Region: YqgFc; smart00732
519441003364	S1_Tex: The C-terminal S1 domain of a transcription accessory factor called Tex, which has been characterized in Bordetella pertussis and Pseudomonas aeruginosa. The tex gene is essential in Bortella pertusis and is named for its role in toxin expression; Region: S1_Tex; cd05685
519441003365	RNA binding site [nucleotide binding]; other site
519441003366	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
519441003367	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
519441003368	RNA binding surface [nucleotide binding]; other site
519441003369	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
519441003370	active site
519441003371	Predicted phosphatases [General function prediction only]; Region: Gph; COG0546
519441003372	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
519441003373	motif II; other site
519441003374	DNA polymerase I; Provisional; Region: PRK05755
519441003375	PIN domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: PIN_53EXO; cd09859
519441003376	active site
519441003377	metal binding site 1 [ion binding]; metal-binding site
519441003378	putative 5' ssDNA interaction site; other site
519441003379	metal binding site 3; metal-binding site
519441003380	metal binding site 2 [ion binding]; metal-binding site
519441003381	H3TH domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: H3TH_53EXO; cd09898
519441003382	putative DNA binding site [nucleotide binding]; other site
519441003383	putative metal binding site [ion binding]; other site
519441003384	DnaQ-like (or DEDD) 3'-5' exonuclease domain superfamily; Region: DnaQ_like_exo; cl10012
519441003385	Polymerase I functions primarily to fill DNA gaps that arise during DNA repair, recombination and replication; Region: DNA_pol_A_pol_I_C; cd08637
519441003386	active site
519441003387	DNA binding site [nucleotide binding]
519441003388	catalytic site [active]
519441003389	Glutaredoxin-like domain protein; Region: GlrX_arch; TIGR02187
519441003390	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
519441003391	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
519441003392	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
519441003393	Walker A/P-loop; other site
519441003394	ATP binding site [chemical binding]; other site
519441003395	Q-loop/lid; other site
519441003396	ABC transporter signature motif; other site
519441003397	Walker B; other site
519441003398	D-loop; other site
519441003399	H-loop/switch region; other site
519441003400	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
519441003401	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
519441003402	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
519441003403	Walker A/P-loop; other site
519441003404	ATP binding site [chemical binding]; other site
519441003405	Q-loop/lid; other site
519441003406	ABC transporter signature motif; other site
519441003407	Walker B; other site
519441003408	D-loop; other site
519441003409	H-loop/switch region; other site
519441003410	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
519441003411	Coproporphyrinogen III oxidase and related Fe-S oxidoreductases [Coenzyme metabolism]; Region: HemN; COG0635
519441003412	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
519441003413	FeS/SAM binding site; other site
519441003414	CAAX protease self-immunity; Region: Abi; pfam02517
519441003415	Preprotein translocase subunit SecF [Intracellular trafficking and secretion]; Region: SecF; COG0341
519441003416	Uncharacterized conserved protein [Function unknown]; Region: COG0327
519441003417	NIF3 (NGG1p interacting factor 3); Region: NIF3; pfam01784
519441003418	Major Facilitator Superfamily; Region: MFS_1; pfam07690
519441003419	The substrate binding component of an ABC-type lactococcal OppA-like transport system contains; Region: PBP2_Lactococcal_OppA_like; cd08510
519441003420	Bacterial extracellular solute-binding proteins, family 5 Middle; Region: SBP_bac_5; pfam00496
519441003421	peptide binding site [polypeptide binding]; other site
519441003422	The substrate binding component of an ABC-type lactococcal OppA-like transport system contains; Region: PBP2_Lactococcal_OppA_like; cd08510
519441003423	Bacterial extracellular solute-binding proteins, family 5 Middle; Region: SBP_bac_5; pfam00496
519441003424	peptide binding site [polypeptide binding]; other site
519441003425	ATP-dependent DNA helicase RecG; Provisional; Region: PRK10917
519441003426	RecG_wedge_OBF: A subfamily of OB folds corresponding to the OB fold found in the N-terminal (wedge) domain of Escherichia coli RecG. RecG is a branched-DNA-specific helicase, which catalyzes the interconversion of a DNA replication fork to a...; Region: RecG_wedge_OBF; cd04488
519441003427	ssDNA binding site; other site
519441003428	generic binding surface II; other site
519441003429	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
519441003430	ATP binding site [chemical binding]; other site
519441003431	putative Mg++ binding site [ion binding]; other site
519441003432	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
519441003433	nucleotide binding region [chemical binding]; other site
519441003434	ATP-binding site [chemical binding]; other site
519441003435	NTPase/HAM1.  This family consists of the HAM1 protein and pyrophosphate-releasing xanthosine/ inosine triphosphatase. HAM1 protects the cell against mutagenesis by the base analog 6-N-hydroxylaminopurine (HAP) in E. Coli and S. cerevisiae. A...; Region: HAM1; cd00515
519441003436	active site
519441003437	dimerization interface [polypeptide binding]; other site
519441003438	recombination regulator RecX; Reviewed; Region: recX; PRK00117
519441003439	recombinase A; Provisional; Region: recA; PRK09354
519441003440	RecA is a  bacterial enzyme which has roles in homologous recombination, DNA repair, and the induction of the SOS response.  RecA couples ATP hydrolysis to DNA strand exchange; Region: recA; cd00983
519441003441	hexamer interface [polypeptide binding]; other site
519441003442	Walker A motif; other site
519441003443	ATP binding site [chemical binding]; other site
519441003444	Walker B motif; other site
519441003445	oligoendopeptidase F; Region: pepF; TIGR00181
519441003446	Peptidase family M3B Oligopeptidase F (PepF); Region: M3B_PepF_3; cd09608
519441003447	active site
519441003448	Zn binding site [ion binding]; other site
519441003449	Mevalonate kinase [Lipid metabolism]; Region: ERG12; COG1577
519441003450	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
519441003451	diphosphomevalonate decarboxylase; Region: mevDPdecarb; TIGR01240
519441003452	diphosphomevalonate decarboxylase; Region: PLN02407
519441003453	mevalonate kinase; Region: mevalon_kin; TIGR00549
519441003454	GHMP kinases C terminal; Region: GHMP_kinases_C; pfam08544
519441003455	peroxiredoxin; Region: AhpC; TIGR03137
519441003456	Peroxiredoxin (PRX) family, Typical 2-Cys PRX subfamily; PRXs are thiol-specific antioxidant (TSA) proteins, which confer a protective role in cells through its peroxidase activity by reducing hydrogen peroxide, peroxynitrite, and organic hydroperoxides; Region: PRX_Typ2cys; cd03015
519441003457	dimer interface [polypeptide binding]; other site
519441003458	decamer (pentamer of dimers) interface [polypeptide binding]; other site
519441003459	catalytic triad [active]
519441003460	peroxidatic and resolving cysteines [active]
519441003461	haloacid dehalogenase-like hydrolase; Region: HAD; pfam12710
519441003462	tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA; Validated; Region: PRK05192
519441003463	putative FAD-binding dehydrogenase; Reviewed; Region: PRK12834
519441003464	tRNA (uracil-5-)-methyltransferase Gid; Reviewed; Region: PRK05335
519441003465	GidA associated domain 3; Region: GIDA_assoc_3; pfam13932
519441003466	Integral membrane protein (intg_mem_TP0381); Region: Intg_mem_TP0381; cl02331
519441003467	ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components [Energy production and conversion / Posttranslational modification, protein turnover, chaperones]; Region: CydD; COG4988
519441003468	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
519441003469	ATP-binding cassette domain of multidrug resistance protein-like transporters; Region: ABCC_MRP_Like; cd03228
519441003470	Walker A/P-loop; other site
519441003471	ATP binding site [chemical binding]; other site
519441003472	Q-loop/lid; other site
519441003473	ABC transporter signature motif; other site
519441003474	Walker B; other site
519441003475	D-loop; other site
519441003476	H-loop/switch region; other site
519441003477	Selenocysteine lyase/Cysteine desulfurase [Posttranslational modification, protein turnover, chaperones]; Region: csdA; COG0520
519441003478	Cysteine desulfurase (SufS)-like. This family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to cysteine desulfurase (SufS) and selenocysteine lyase. SufS...; Region: SufS_like; cd06453
519441003479	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
519441003480	catalytic residue [active]
519441003481	cysteine desulfurase activator complex subunit SufB; Provisional; Region: PRK11814; cl03223
519441003482	Uncharacterized protein family (UPF0051); Region: UPF0051; pfam01458
519441003483	FeS assembly protein SufB; Region: sufB; TIGR01980
519441003484	cysteine desulfurase activator complex subunit SufB; Provisional; Region: PRK11814; cl03223
519441003485	Cysteine desulfurase activator ATPase [Posttranslational modification, protein turnover, chaperones]; Region: sufC; COG0396
519441003486	ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Region: ABC_FeS_Assembly; cd03217
519441003487	Walker A/P-loop; other site
519441003488	ATP binding site [chemical binding]; other site
519441003489	Q-loop/lid; other site
519441003490	ABC transporter signature motif; other site
519441003491	Walker B; other site
519441003492	D-loop; other site
519441003493	H-loop/switch region; other site
519441003494	Carboxylate/Amino Acid/Amine Transporter; Region: 2A78; TIGR00950
519441003495	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
519441003496	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
519441003497	Walker A/P-loop; other site
519441003498	ATP binding site [chemical binding]; other site
519441003499	Q-loop/lid; other site
519441003500	ABC transporter signature motif; other site
519441003501	Walker B; other site
519441003502	D-loop; other site
519441003503	H-loop/switch region; other site
519441003504	Transketolase, C-terminal subunit [Carbohydrate transport and metabolism]; Region: COG3958
519441003505	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
519441003506	PYR/PP interface [polypeptide binding]; other site
519441003507	dimer interface [polypeptide binding]; other site
519441003508	TPP binding site [chemical binding]; other site
519441003509	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
519441003510	transketolase; Reviewed; Region: PRK05899
519441003511	Thiamine pyrophosphate (TPP) family, Transketolase (TK) subfamily, TPP-binding module; TK catalyzes the transfer of a two-carbon unit from ketose phosphates to aldose phosphates. In heterotrophic organisms, TK provides a link between glycolysis and the...; Region: TPP_TK; cd02012
519441003512	TPP-binding site [chemical binding]; other site
519441003513	dimer interface [polypeptide binding]; other site
519441003514	PTS system ascorbate-specific transporter subunit IIC; Reviewed; Region: ulaA; PRK09410
519441003515	PTS_IIB_ascorbate: subunit IIB of enzyme II (EII) of the L-ascorbate-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is an L-ascorbate-specific permease with two cytoplasmic subunits (IIA and IIB) and a...; Region: PTS_IIB_ascorbate; cd05563
519441003516	active site
519441003517	P-loop; other site
519441003518	phosphorylation site [posttranslational modification]
519441003519	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
519441003520	active site
519441003521	phosphorylation site [posttranslational modification]
519441003522	Transcriptional antiterminator [Transcription]; Region: BglG; COG3711
519441003523	PRD domain; Region: PRD; pfam00874
519441003524	PTS_IIB_bgl_like: the PTS (phosphotransferase system) IIB domain of a family of sensory systems composed of a membrane-bound sugar-sensor (similar to BglF) and a transcription antiterminator (similar to BglG) which regulate expression of genes involved...; Region: PTS_IIB_bgl_like; cd05568
519441003525	active site
519441003526	P-loop; other site
519441003527	phosphorylation site [posttranslational modification]
519441003528	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
519441003529	active site
519441003530	phosphorylation site [posttranslational modification]
519441003531	N-methylhydantoinase B/acetone carboxylase, alpha subunit [Amino acid transport and metabolism / Secondary metabolites biosynthesis, transport, and catabolism]; Region: HyuB; COG0146
519441003532	haemagglutination activity domain; Region: Haemagg_act; cl05436
519441003533	acid phosphatase/phosphotransferase; Provisional; Region: aphA; PRK11009
519441003534	haloacid dehalogenase superfamily, subfamily IA, variant 1 with third motif having Dx(3-4)D or Dx(3-4)E; Region: HAD-SF-IA-v1; TIGR01549
519441003535	Topoisomerase IA [DNA replication, recombination, and repair]; Region: TopA; COG0550
519441003536	TOPRIM_TopoIA_TopoIII: The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to topoisomerase III. Type IA DNA topoisomerases remove (relax) negative supercoils in the DNA by: cleaving...; Region: TOPRIM_TopoIA_TopoIII; cd03362
519441003537	active site
519441003538	putative interdomain interaction site [polypeptide binding]; other site
519441003539	putative metal-binding site [ion binding]; other site
519441003540	putative nucleotide binding site [chemical binding]; other site
519441003541	DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cl11986
519441003542	domain I; other site
519441003543	DNA binding groove [nucleotide binding]
519441003544	phosphate binding site [ion binding]; other site
519441003545	domain II; other site
519441003546	domain III; other site
519441003547	nucleotide binding site [chemical binding]; other site
519441003548	catalytic site [active]
519441003549	domain IV; other site
519441003550	Antirestriction protein [DNA replication, recombination, and repair]; Region: COG4227
519441003551	Domain of unknown function (DUF1738); Region: DUF1738; pfam08401
519441003552	Protein of unknown function (DUF3991); Region: DUF3991; pfam13154
519441003553	Toprim-like; Region: Toprim_2; pfam13155
519441003554	NlpC/P60 family; Region: NLPC_P60; pfam00877
519441003555	Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]; Region: Spr; COG0791
519441003556	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
519441003557	Outer membrane protein and related peptidoglycan-associated (lipo)proteins [Cell envelope biogenesis, outer membrane]; Region: OmpA; COG2885
519441003558	ligand binding site [chemical binding]; other site
519441003559	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
519441003560	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
519441003561	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
519441003562	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
519441003563	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
519441003564	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
519441003565	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
519441003566	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
519441003567	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
519441003568	Conjugal transfer protein TraD; Region: TraD; cl05753
519441003569	Type IV secretory pathway, protease TraF [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: TraF; COG4959
519441003570	TrbL/VirB6 plasmid conjugal transfer protein; Region: TrbL; pfam04610
519441003571	transcription factor, RsfA family; Region: DNA_bind_RsfA; TIGR02894
519441003572	TrbL/VirB6 plasmid conjugal transfer protein; Region: TrbL; cl01503
519441003573	conjugal transfer ATPase TrbE; Provisional; Region: PRK13873
519441003574	CagE, TrbE, VirB family, component of type IV transporter system; Region: CagE_TrbE_VirB; pfam03135
519441003575	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
519441003576	Walker A motif; other site
519441003577	ATP binding site [chemical binding]; other site
519441003578	Type IV secretory pathway, VirB3-like protein; Region: VirB3; cl01501
519441003579	YadA-like C-terminal region; Region: YadA; pfam03895
519441003580	P-type conjugative transfer ATPase TrbB; Region: TrbB_P; TIGR02782
519441003581	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
519441003582	Walker A motif; other site
519441003583	ATP binding site [chemical binding]; other site
519441003584	Walker B motif; other site
519441003585	Type IV secretory system Conjugative DNA transfer; Region: T4SS-DNA_transf; pfam02534
519441003586	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
519441003587	Walker A motif; other site
519441003588	ATP binding site [chemical binding]; other site
519441003589	Walker B motif; other site
519441003590	Bacterial conjugation TrbI-like protein; Region: TrbI; pfam03743
519441003591	VirB9/CagX/TrbG, a component of the type IV secretion system; Region: VirB9_CagX_TrbG; cd06911
519441003592	VirB7 interaction site; other site
519441003593	Orbivirus outer capsid protein VP5; Region: Orbi_VP5; pfam00901
519441003594	VirB8 protein; Region: VirB8; pfam04335
519441003595	MobA/MobL family; Region: MobA_MobL; pfam03389
519441003596	BRO family, N-terminal domain; Region: Bro-N; smart01040
519441003597	Replication initiator protein A (RepA) N-terminus; Region: RepA_N; pfam06970
519441003598	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
519441003599	non-specific DNA binding site [nucleotide binding]; other site
519441003600	salt bridge; other site
519441003601	sequence-specific DNA binding site [nucleotide binding]; other site
519441003602	Site-specific recombinase XerD [DNA replication, recombination, and repair]; Region: XerD; COG4974
519441003603	DNA breaking-rejoining enzymes, intergrase/recombinases, C-terminal catalytic domain. The tyrosine recombinase/integrase family share the same catalytic domain containing six conserved active site residues. The best-studied members of this diverse family...; Region: INT_REC_C; cd01182
519441003604	active site
519441003605	catalytic residues [active]
519441003606	DNA binding site [nucleotide binding]
519441003607	Int/Topo IB signature motif; other site
519441003608	PASTA domain of bacterial serine/threonine kinase pknB-like proteins. PknB is a member of a group of related transmembrane sensor kinases present in many gram positive bacteria, which has been shown to regulate cell shape in Mycobacterium tubercolosis; Region: PASTA_pknB; cd06577
519441003609	PASTA domain of bacterial serine/threonine kinase pknB-like proteins. PknB is a member of a group of related transmembrane sensor kinases present in many gram positive bacteria, which has been shown to regulate cell shape in Mycobacterium tubercolosis; Region: PASTA_pknB; cd06577
519441003610	PASTA domain of bacterial serine/threonine kinase pknB-like proteins. PknB is a member of a group of related transmembrane sensor kinases present in many gram positive bacteria, which has been shown to regulate cell shape in Mycobacterium tubercolosis; Region: PASTA_pknB; cd06577
519441003611	Predicted GTPases [General function prediction only]; Region: COG1162
519441003612	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
519441003613	RNA binding site [nucleotide binding]; other site
519441003614	Ribosomal interacting GTPase YjeQ/EngC, a circularly permuted subfamily of the Ras GTPases; Region: YjeQ_EngC; cd01854
519441003615	GTPase/Zn-binding domain interface [polypeptide binding]; other site
519441003616	GTP/Mg2+ binding site [chemical binding]; other site
519441003617	G4 box; other site
519441003618	G1 box; other site
519441003619	Switch I region; other site
519441003620	G2 box; other site
519441003621	G3 box; other site
519441003622	Switch II region; other site
519441003623	Pentose-5-phosphate-3-epimerase [Carbohydrate transport and metabolism]; Region: Rpe; COG0036
519441003624	Ribulose-5-phosphate 3-epimerase (RPE). This enzyme catalyses the interconversion of D-ribulose 5-phosphate (Ru5P) into D-xylulose 5-phosphate, as part of the Calvin cycle (reductive pentose phosphate pathway) in chloroplasts and in the oxidative pentose...; Region: RPE; cd00429
519441003625	substrate binding site [chemical binding]; other site
519441003626	hexamer interface [polypeptide binding]; other site
519441003627	metal binding site [ion binding]; metal-binding site
519441003628	MarR family; Region: MarR; pfam01047
519441003629	FeoA domain; Region: FeoA; pfam04023
519441003630	Fibronectin-binding protein A N-terminus (FbpA); Region: FbpA; pfam05833
519441003631	Domain of unknown function (DUF814); Region: DUF814; pfam05670
519441003632	6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase [Carbohydrate transport and metabolism]; Region: NagB; COG0363
519441003633	GlcN6P_deaminase: Glucosamine-6-phosphate (GlcN6P) deaminase subfamily; GlcN6P deaminase catalyzes the reversible conversion of GlcN6P to D-fructose-6-phosphate (Fru6P) and ammonium. The reaction is an aldo-keto isomerization coupled with an amination or...; Region: GlcN6P_deaminase; cd01399
519441003634	active site
519441003635	trimer interface [polypeptide binding]; other site
519441003636	allosteric site; other site
519441003637	active site lid [active]
519441003638	hexamer (dimer of trimers) interface [polypeptide binding]; other site
519441003639	Acetyltransferase (GNAT) domain; Region: Acetyltransf_8; pfam13523
519441003640	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
519441003641	Coenzyme A binding pocket [chemical binding]; other site
519441003642	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
519441003643	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
519441003644	DNA binding site [nucleotide binding]
519441003645	Sialidases or neuraminidases function to bind and hydrolyze terminal sialic acid residues from various glycoconjugates as well as playing roles in pathogenesis, bacterial nutrition and cellular interactions. They have a six-bladed, beta-propeller fold...; Region: Sialidase; cd00260
519441003646	BNR repeat-like domain; Region: BNR_2; pfam13088
519441003647	Asp-box motif; other site
519441003648	catalytic site [active]
519441003649	GAF domain-containing protein [Signal transduction mechanisms]; Region: COG1956
519441003650	GAF domain; Region: GAF_2; pfam13185
519441003651	Lipoate-protein ligase A [Coenzyme metabolism]; Region: LplA; COG0095
519441003652	lipoyltransferase and lipoate-protein ligase; Region: lipoyltrans; TIGR00545
519441003653	Bacterial lipoate protein ligase C-terminus; Region: Lip_prot_lig_C; pfam10437
519441003654	adenosine deaminase; Provisional; Region: PRK09358
519441003655	Adenosine deaminase [Nucleotide transport and metabolism]; Region: Add; COG1816
519441003656	active site
519441003657	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
519441003658	E3 interaction surface; other site
519441003659	lipoyl attachment site [posttranslational modification]; other site
519441003660	dihydrolipoamide dehydrogenase; Region: lipoamide_DH; TIGR01350
519441003661	Anaerobic glycerol-3-phosphate dehydrogenase [Amino acid transport and metabolism]; Region: GlpB; cl17730
519441003662	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
519441003663	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
519441003664	dihydrolipoamide acetyltransferase; Provisional; Region: PRK14843
519441003665	e3 binding domain; Region: E3_binding; pfam02817
519441003666	e3 binding domain; Region: E3_binding; pfam02817
519441003667	2-oxoacid dehydrogenases acyltransferase (catalytic domain); Region: 2-oxoacid_dh; pfam00198
519441003668	Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit [Energy production and conversion]; Region: AcoB; COG0022
519441003669	Pyrimidine (PYR) binding domain of the beta subunits of the E1 components of human pyruvate dehydrogenase complex (E1- PDHc) and related proteins; Region: TPP_PYR_E1-PDHc-beta_like; cd07036
519441003670	alpha subunit interface [polypeptide binding]; other site
519441003671	TPP binding site [chemical binding]; other site
519441003672	heterodimer interface [polypeptide binding]; other site
519441003673	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
519441003674	Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit [Energy production and conversion]; Region: AcoA; COG1071
519441003675	Thiamine pyrophosphate (TPP) family, E1 of PDC_ADC_BCADC subfamily, TPP-binding module; composed of proteins similar to the E1 components of the human pyruvate dehydrogenase complex (PDC), the acetoin dehydrogenase complex (ADC) and the branched chain...; Region: TPP_E1_PDC_ADC_BCADC; cd02000
519441003676	tetramer interface [polypeptide binding]; other site
519441003677	TPP-binding site [chemical binding]; other site
519441003678	heterodimer interface [polypeptide binding]; other site
519441003679	phosphorylation loop region [posttranslational modification]
519441003680	Pertactin-like passenger domains (virulence factors) of autotransporter proteins of the type V secretion system. Autotransporters are proteins used by Gram-negative bacteria to transport proteins across their outer membranes. The C-terminal (beta) domain...; Region: PL_Passenger_AT; cd00253
519441003681	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
519441003682	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
519441003683	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
519441003684	Walker A/P-loop; other site
519441003685	ATP binding site [chemical binding]; other site
519441003686	Q-loop/lid; other site
519441003687	ABC transporter signature motif; other site
519441003688	Walker B; other site
519441003689	D-loop; other site
519441003690	H-loop/switch region; other site
519441003691	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
519441003692	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
519441003693	ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Region: ABCC_Glucan_exporter_like; cd03254
519441003694	Walker A/P-loop; other site
519441003695	ATP binding site [chemical binding]; other site
519441003696	Q-loop/lid; other site
519441003697	ABC transporter signature motif; other site
519441003698	Walker B; other site
519441003699	D-loop; other site
519441003700	H-loop/switch region; other site
519441003701	Xaa-Pro aminopeptidase [Amino acid transport and metabolism]; Region: PepP; COG0006
519441003702	Creatinase/Prolidase N-terminal domain; Region: Creatinase_N; pfam01321
519441003703	Similar to Prolidase and Aminopeptidase P. The members of this subfamily presumably catalyse hydrolysis of Xaa-Pro dipeptides and/or release of any N-terminal amino acid, including proline, that is linked with proline; Region: APP-like; cd01092
519441003704	active site
519441003705	CAAX protease self-immunity; Region: Abi; pfam02517
519441003706	Membrane protease subunits, stomatin/prohibitin homologs [Posttranslational modification, protein turnover, chaperones]; Region: HflC; COG0330
519441003707	Band_7_stomatin_like: A subgroup of the band 7 domain of flotillin (reggie) like proteins similar to stomatin and podicin (two lipid raft-associated integral membrane proteins). Individual proteins of this band 7 domain family may cluster to form...; Region: Band_7_stomatin_like; cd03403
519441003708	Membrane protein implicated in regulation of membrane protease activity [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: COG1585
519441003709	delta-lactam-biosynthetic de-N-acetylase; Region: spore_pdaA; TIGR02884
519441003710	Catalytic NodB homology domain of Clostridium thermocellum acetylxylan esterase and its bacterial homologs; Region: CE4_CtAXE_like; cd10954
519441003711	NodB motif; other site
519441003712	active site
519441003713	catalytic site [active]
519441003714	Abi-like protein; Region: Abi_2; pfam07751
519441003715	This family contains NADPH-dependent flavin reductase and oxygen-insensitive nitroreductase. These enzymes are homodimeric flavoproteins that contain one FMN per monomer as a cofactor. Flavin reductase catalyzes the reduction of flavin by using NADPH as...; Region: NfsA_FRP; cd02146
519441003716	dimer interface [polypeptide binding]; other site
519441003717	FMN binding site [chemical binding]; other site
519441003718	NADPH bind site [chemical binding]; other site
519441003719	glucose-1-phosphatase/inositol phosphatase; Provisional; Region: PRK10173
519441003720	Histidine phosphatase domain found in a functionally diverse set of proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP; cd07040
519441003721	catalytic core [active]
519441003722	4Fe-4S single cluster domain; Region: Fer4_12; pfam13353
519441003723	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
519441003724	FeS/SAM binding site; other site
519441003725	anaerobic ribonucleoside triphosphate reductase; Provisional; Region: PRK09263
519441003726	ATP cone domain; Region: ATP-cone; pfam03477
519441003727	Ribonucleotide reductase and Pyruvate formate lyase; Region: RNR_PFL; cl09939
519441003728	Transposase zinc-binding domain; Region: Zn_Tnp_IS91; pfam14319
519441003729	Putative transposase; Region: Y2_Tnp; pfam04986
519441003730	Superoxide dismutase [Inorganic ion transport and metabolism]; Region: SodA; COG0605
519441003731	Iron/manganese superoxide dismutases, alpha-hairpin domain; Region: Sod_Fe_N; pfam00081
519441003732	Iron/manganese superoxide dismutases, C-terminal domain; Region: Sod_Fe_C; pfam02777
519441003733	This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases superfamily  includes N type ATP PPases and ATP sulphurylases. It forms a apha/beta/apha fold which  binds to Adenosine group.  This subfamily; Region: Alpha_ANH_like_II; cd01993
519441003734	Ligand Binding Site [chemical binding]; other site
519441003735	YadA-like, left-handed beta-roll; Region: LbR_YadA-like; cd12820
519441003736	trimer interface [polypeptide binding]; other site
519441003737	YadA-like, left-handed beta-roll; Region: LbR_YadA-like; cd12820
519441003738	trimer interface [polypeptide binding]; other site
519441003739	YadA-like, left-handed beta-roll; Region: LbR_YadA-like; cd12820
519441003740	trimer interface [polypeptide binding]; other site
519441003741	Haemagglutinin; Region: HIM; pfam05662
519441003742	YadA-like C-terminal region; Region: YadA; pfam03895
519441003743	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
519441003744	ligand binding site [chemical binding]; other site
519441003745	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
519441003746	metal-binding site [ion binding]
519441003747	ATPase, P-type (transporting), HAD superfamily, subfamily IC; Region: ATPase_P-type; TIGR01494
519441003748	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
519441003749	Soluble P-type ATPase [General function prediction only]; Region: COG4087
519441003750	Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group...; Region: Cyt_C5_DNA_methylase; cd00315
519441003751	DNA-methyltransferase (dcm); Region: dcm; TIGR00675
519441003752	cofactor binding site; other site
519441003753	DNA binding site [nucleotide binding]
519441003754	substrate interaction site [chemical binding]; other site
519441003755	Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group...; Region: Cyt_C5_DNA_methylase; cd00315
519441003756	NgoBV restriction endonuclease; Region: RE_NgoBV; pfam09564
519441003757	N-acetylglucosamine-6-phosphate deacetylase [Carbohydrate transport and metabolism]; Region: NagA; COG1820
519441003758	N-acetylglucosamine-6-phosphate deacetylase, NagA, catalyzes the hydrolysis of the N-acetyl group of N-acetyl-glucosamine-6-phosphate (GlcNAc-6-P) to glucosamine 6-phosphate and acetate. This is the first committed step in the biosynthetic pathway to...; Region: NagA; cd00854
519441003759	active site
519441003760	dimer interface [polypeptide binding]; other site
519441003761	Helical backbone metal receptor (TroA-like domain). These proteins have been shown to function in the ABC transport of ferric siderophores and metal ions such as Mn2+, Fe3+, Cu2+ and/or Zn2+.  Their ligand binding site is formed in the interface between...; Region: TroA-like; cl00262
519441003762	Periplasmic solute binding protein family; Region: SBP_bac_9; pfam01297
519441003763	intersubunit interface [polypeptide binding]; other site
519441003764	Thiamine pyrophosphokinase; Region: TPK; cd07995
519441003765	thiamine pyrophosphokinase; Region: thi_PPkinase; TIGR01378
519441003766	active site
519441003767	dimerization interface [polypeptide binding]; other site
519441003768	thiamine binding site [chemical binding]; other site
519441003769	phenylalanyl-tRNA synthetase subunit beta; Reviewed; Region: pheT; PRK00629
519441003770	tRNA-binding-domain-containing prokaryotic phenylalanly tRNA synthetase (PheRS) beta chain.  PheRS aminoacylate phenylalanine transfer RNAs (tRNAphe). PheRSs belong structurally to class II aminoacyl tRNA synthetases (aaRSs) but, as they aminoacylate...; Region: tRNA_bind_bactPheRS; cd02796
519441003771	putative tRNA-binding site [nucleotide binding]; other site
519441003772	B3/4 domain; Region: B3_4; pfam03483
519441003773	tRNA synthetase B5 domain; Region: B5; smart00874
519441003774	Phenylalanyl-tRNA synthetase (PheRS) beta chain core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure. While class II aaRSs generally aminoacylate the 3'-OH ribose of the appropriate tRNA,  PheRS is an...; Region: PheRS_beta_core; cd00769
519441003775	dimer interface [polypeptide binding]; other site
519441003776	motif 1; other site
519441003777	motif 3; other site
519441003778	motif 2; other site
519441003779	Ferredoxin-fold anticodon binding domain; Region: FDX-ACB; smart00896
519441003780	phenylalanyl-tRNA synthetase subunit alpha; Validated; Region: pheS; PRK00488
519441003781	Aminoacyl tRNA synthetase class II, N-terminal domain; Region: Phe_tRNA-synt_N; pfam02912
519441003782	Phenylalanyl-tRNA synthetase (PheRS) alpha chain catalytic core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure and the presence of three characteristic sequence motifs. This domain is primarily responsible...; Region: PheRS_alpha_core; cd00496
519441003783	dimer interface [polypeptide binding]; other site
519441003784	motif 1; other site
519441003785	active site
519441003786	motif 2; other site
519441003787	motif 3; other site
519441003788	Large-conductance mechanosensitive channel, MscL; Region: MscL; cl00860
519441003789	Escherichia coli YfcE and related proteins, metallophosphatase domain; Region: MPP_YfcE; cd00841
519441003790	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
519441003791	active site
519441003792	metal binding site [ion binding]; metal-binding site
519441003793	homotetramer interface [polypeptide binding]; other site
519441003794	DNA gyrase subunit A; Validated; Region: PRK05560
519441003795	DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes...; Region: TOP4c; cd00187
519441003796	CAP-like domain; other site
519441003797	active site
519441003798	primary dimer interface [polypeptide binding]; other site
519441003799	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
519441003800	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
519441003801	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
519441003802	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
519441003803	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
519441003804	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
519441003805	DNA gyrase subunit B; Validated; Region: gyrB; PRK05644
519441003806	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
519441003807	ATP binding site [chemical binding]; other site
519441003808	Mg2+ binding site [ion binding]; other site
519441003809	G-X-G motif; other site
519441003810	TopoIIA_Trans_DNA_gyrase: Transducer domain, having a ribosomal S5 domain 2-like fold, of the type found in proteins of the type IIA family of DNA topoisomerases similar to the B subunits of E. coli DNA gyrase and E. coli Topoisomerase IV which are; Region: TopoII_Trans_DNA_gyrase; cd00822
519441003811	anchoring element; other site
519441003812	dimer interface [polypeptide binding]; other site
519441003813	ATP binding site [chemical binding]; other site
519441003814	TOPRIM_TopoIIA_GyrB: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in proteins of the type IIA family of DNA topoisomerases similar to the Escherichia coli GyrB subunit. TopoIIA enzymes cut both strands of the...; Region: TOPRIM_TopoIIA_GyrB; cd03366
519441003815	active site
519441003816	putative metal-binding site [ion binding]; other site
519441003817	DNA gyrase B subunit, carboxyl terminus; Region: DNA_gyraseB_C; pfam00986
519441003818	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
519441003819	RNA binding surface [nucleotide binding]; other site
519441003820	RNA recognition motif (RRM) superfamily; Region: RRM_SF; cl17169
519441003821	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
519441003822	RNA binding surface [nucleotide binding]; other site
519441003823	preprotein translocase subunit SecY; Reviewed; Region: secY; PRK09204
519441003824	SecY translocase; Region: SecY; pfam00344
519441003825	50S ribosomal protein L15; Reviewed; Region: rplO; PRK05592
519441003826	Ribosomal protein L30, which is found in eukaryotes and prokaryotes but not in archaea, is one of the smallest ribosomal proteins with a molecular mass of about 7kDa. L30 binds the 23SrRNA as well as the 5S rRNA and is one of five ribosomal proteins that...; Region: Ribosomal_L30; cd01658
519441003827	23S rRNA binding site [nucleotide binding]; other site
519441003828	30S ribosomal protein S5; Validated; Region: rpsE; PRK00550
519441003829	Ribosomal protein S5, N-terminal domain; Region: Ribosomal_S5; pfam00333
519441003830	Ribosomal protein S5, C-terminal domain; Region: Ribosomal_S5_C; pfam03719
519441003831	Ribosomal L18/L5e:  L18 (L5e) is a ribosomal protein found in the central protuberance (CP) of the large subunit. L18 binds 5S rRNA and induces a conformational change that stimulates the binding of L5 to 5S rRNA. Association of 5S rRNA with 23S rRNA...; Region: Ribosomal_L18_L5e; cd00432
519441003832	23S rRNA interface [nucleotide binding]; other site
519441003833	L21e interface [polypeptide binding]; other site
519441003834	5S rRNA interface [nucleotide binding]; other site
519441003835	L27 interface [polypeptide binding]; other site
519441003836	L5 interface [polypeptide binding]; other site
519441003837	50S ribosomal protein L6; Validated; Region: rplF; PRK05498
519441003838	Ribosomal protein L6; Region: Ribosomal_L6; pfam00347
519441003839	Ribosomal protein L6; Region: Ribosomal_L6; pfam00347
519441003840	30S ribosomal protein S8; Validated; Region: rpsH; PRK00136
519441003841	30S ribosomal protein S14; Reviewed; Region: rpsN; PRK08881
519441003842	50S ribosomal protein L5; Validated; Region: rplE; PRK00010
519441003843	Ribosomal protein L5; Region: Ribosomal_L5; pfam00281
519441003844	ribosomal L5P family C-terminus; Region: Ribosomal_L5_C; pfam00673
519441003845	50S ribosomal protein L24; Reviewed; Region: rplX; PRK00004
519441003846	KOW motif of Ribosomal Protein L26; Region: KOW_RPL26; cd06089
519441003847	RNA binding site [nucleotide binding]; other site
519441003848	50S ribosomal protein L14; Validated; Region: rplN; PRK05483
519441003849	30S ribosomal protein S17; Reviewed; Region: rpsQ; PRK05610
519441003850	Ribosomal L29 protein/HIP.  L29 is a protein of the large ribosomal Subunit. A homolog, called heparin/heparan sulfate interacting protein (HIP), has also been identified in mammals.  L29 is located on the surface of the large ribosomal subunit, where it...; Region: Ribosomal_L29_HIP; cd00427
519441003851	23S rRNA interface [nucleotide binding]; other site
519441003852	putative translocon interaction site; other site
519441003853	signal recognition particle (SRP54) interaction site; other site
519441003854	L23 interface [polypeptide binding]; other site
519441003855	trigger factor interaction site; other site
519441003856	Ribosomal_L16_L10e: L16 is an essential protein in the large ribosomal subunit of bacteria, mitochondria, and chloroplasts. Large subunits that lack L16 are defective in peptidyl transferase activity, peptidyl-tRNA hydrolysis activity, association with...; Region: Ribosomal_L16_L10e; cd01433
519441003857	23S rRNA interface [nucleotide binding]; other site
519441003858	5S rRNA interface [nucleotide binding]; other site
519441003859	putative antibiotic binding site [chemical binding]; other site
519441003860	L25 interface [polypeptide binding]; other site
519441003861	L27 interface [polypeptide binding]; other site
519441003862	30S ribosomal protein S3; Reviewed; Region: rpsC; PRK00310
519441003863	K homology RNA-binding (KH) domain of the prokaryotic 30S small ribosomal subunit protein S3. S3  is part of the head region of the 30S ribosomal subunit and is believed to interact with mRNA as it threads its way from the latch into the channel.  The KH...; Region: 30S_S3_KH; cd02412
519441003864	G-X-X-G motif; other site
519441003865	Ribosomal protein S3, C-terminal domain; Region: Ribosomal_S3_C; pfam00189
519441003866	Ribosomal protein L22/L17e.  L22 (L17 in eukaryotes) is a core protein of the large ribosomal subunit.  It is the only ribosomal protein that interacts with all six domains of 23S rRNA, and is one of the proteins important for directing the proper...; Region: Ribosomal_L22; cd00336
519441003867	putative translocon binding site; other site
519441003868	protein-rRNA interface [nucleotide binding]; other site
519441003869	30S ribosomal protein S19; Reviewed; Region: rpsS; PRK00357
519441003870	50S ribosomal protein L2; Validated; Region: rplB; PRK09374
519441003871	Ribosomal Proteins L2, RNA binding domain; Region: Ribosomal_L2; pfam00181
519441003872	Ribosomal Proteins L2, C-terminal domain; Region: Ribosomal_L2_C; pfam03947
519441003873	Pertactin-like passenger domains (virulence factors) of autotransporter proteins of the type V secretion system. Autotransporters are proteins used by Gram-negative bacteria to transport proteins across their outer membranes. The C-terminal (beta) domain...; Region: PL_Passenger_AT; cd00253
519441003874	outer membrane autotransporter barrel domain; Region: autotrans_barl; TIGR01414
519441003875	Autotransporter beta-domain; Region: Autotransporter; pfam03797
519441003876	Predicted membrane protein, putative toxin regulator [General function prediction only]; Region: PfoR; COG3641
519441003877	Phosphotransferase system, EIIC; Region: PTS_EIIC_2; pfam13303
519441003878	2-dehydropantoate 2-reductase; Reviewed; Region: PRK06522
519441003879	Ketopantoate reductase PanE/ApbA; Region: ApbA; pfam02558
519441003880	Ketopantoate reductase PanE/ApbA C terminal; Region: ApbA_C; pfam08546
519441003881	PemK-like protein; Region: PemK; pfam02452
519441003882	Protein of unknown function (DUF4065); Region: DUF4065; pfam13274
519441003883	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
519441003884	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
519441003885	active site
519441003886	catalytic tetrad [active]
519441003887	Peptidase C1B subfamily (MEROPS database nomenclature); composed of eukaryotic bleomycin hydrolases (BH) and bacterial aminopeptidases C (pepC). The proteins of this subfamily contain a large insert relative to the C1A peptidase (papain) subfamily. BH is...; Region: Peptidase_C1B; cd00585
519441003888	trimer interface [polypeptide binding]; other site
519441003889	active site
519441003890	G bulge; other site
519441003891	Class II hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase (HMGR); Region: HMG-CoA_reductase_classII; cd00644
519441003892	homodimer interface [polypeptide binding]; other site
519441003893	catalytic residues [active]
519441003894	NAD binding site [chemical binding]; other site
519441003895	substrate binding pocket [chemical binding]; other site
519441003896	flexible flap; other site
519441003897	"initiating" condensing enzymes are a subclass of decarboxylating condensing enzymes, including beta-ketoacyl [ACP] synthase, type III and polyketide synthases, type III, which include chalcone synthase and related enzymes. They are...; Region: init_cond_enzymes; cd00827
519441003898	3-hydroxy-3-methylglutaryl CoA synthase, prokaryotic clade; Region: HMG-CoA-S_prok; TIGR01835
519441003899	dimer interface [polypeptide binding]; other site
519441003900	active site
519441003901	putative acyltransferase; Provisional; Region: PRK05790
519441003902	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
519441003903	dimer interface [polypeptide binding]; other site
519441003904	active site
519441003905	Membrane-bound lysozyme-inhibitor of c-type lysozyme; Region: MliC; cl01604
519441003906	glucose-6-phosphate isomerase; Provisional; Region: pgi; PRK14097
519441003907	Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the first SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_1; cd05015
519441003908	active site
519441003909	dimer interface [polypeptide binding]; other site
519441003910	Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the second SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_2; cd05016
519441003911	dimer interface [polypeptide binding]; other site
519441003912	active site
519441003913	Domain of unknown function (DUF956); Region: DUF956; pfam06115
519441003914	Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IID [Carbohydrate transport and metabolism]; Region: ManZ; COG3716
519441003915	PTS system mannose-specific transporter subunit IIC; Provisional; Region: PRK15065
519441003916	Protein of unknown function (DUF1648); Region: DUF1648; pfam07853
519441003917	SdpI/YhfL protein family; Region: SdpI; pfam13630
519441003918	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
519441003919	dimerization interface [polypeptide binding]; other site
519441003920	putative DNA binding site [nucleotide binding]; other site
519441003921	putative Zn2+ binding site [ion binding]; other site
519441003922	D-mannonate oxidoreductase; Provisional; Region: PRK08277
519441003923	putative D-mannonate oxidoreductase, classical (c) SDR; Region: mannonate_red_SDR_c; cd08935
519441003924	putative NAD(P) binding site [chemical binding]; other site
519441003925	active site
519441003926	mannonate dehydratase; Provisional; Region: PRK03906
519441003927	mannonate dehydratase; Region: uxuA; TIGR00695
519441003928	glucuronate isomerase; Reviewed; Region: PRK02925
519441003929	Glucuronate isomerase [Carbohydrate transport and metabolism]; Region: UxaC; COG1904
519441003930	Transcriptional regulators [Transcription]; Region: PurR; COG1609
519441003931	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
519441003932	DNA binding site [nucleotide binding]
519441003933	domain linker motif; other site
519441003934	Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267
519441003935	dimerization interface [polypeptide binding]; other site
519441003936	ligand binding site [chemical binding]; other site
519441003937	MFS/sugar transport protein; Region: MFS_2; pfam13347
519441003938	melibiose:sodium symporter; Provisional; Region: PRK10429; cl15392
519441003939	beta-D-glucuronidase; Provisional; Region: PRK10150
519441003940	Glycosyl hydrolases family 2, sugar binding domain; Region: Glyco_hydro_2_N; pfam02837
519441003941	Glycosyl hydrolases family 2; Region: Glyco_hydro_2; pfam00703
519441003942	Glycosyl hydrolases family 2, TIM barrel domain; Region: Glyco_hydro_2_C; pfam02836
519441003943	Beta-glucosidase-related glycosidases [Carbohydrate transport and metabolism]; Region: BglX; COG1472
519441003944	Glycosyl hydrolase family 3 N terminal domain; Region: Glyco_hydro_3; cl07971
519441003945	haloacid dehalogenase-like hydrolase; Region: Hydrolase; pfam00702
519441003946	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cl17915
519441003947	motif II; other site
519441003948	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
519441003949	non-specific DNA binding site [nucleotide binding]; other site
519441003950	salt bridge; other site
519441003951	sequence-specific DNA binding site [nucleotide binding]; other site
519441003952	L-ribulose-5-phosphate 4-epimerase; Reviewed; Region: araD; PRK08193
519441003953	Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II); Region: Aldolase_II; cd00398
519441003954	intersubunit interface [polypeptide binding]; other site
519441003955	active site
519441003956	Zn2+ binding site [ion binding]; other site
519441003957	putative L-xylulose 5-phosphate 3-epimerase; Reviewed; Region: PRK13210
519441003958	AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cl12060
519441003959	AP (apurinic/apyrimidinic) site pocket; other site
519441003960	DNA interaction; other site
519441003961	Metal-binding active site; metal-binding site
519441003962	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
519441003963	active site
519441003964	phosphorylation site [posttranslational modification]
519441003965	PTS_IIB: subunit IIB of enzyme II (EII) is the central energy-coupling domain of the phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In the multienzyme PTS complex, EII is a carbohydrate-specific permease consisting of two cytoplasmic...; Region: PTS_IIB; cl10014
519441003966	active site
519441003967	P-loop; other site
519441003968	phosphorylation site [posttranslational modification]
519441003969	PTS system ascorbate-specific transporter subunit IIC; Reviewed; Region: PRK12997
519441003970	putative L-ascorbate 6-phosphate lactonase; Provisional; Region: PRK11709
519441003971	Predicted Zn-dependent hydrolases of the beta-lactamase fold [General function prediction only]; Region: COG2220
519441003972	Carbon starvation protein, predicted membrane protein [Signal transduction mechanisms]; Region: CstA; COG1966
519441003973	Carbon starvation protein CstA; Region: CstA; pfam02554
519441003974	C-terminal domain on CstA (DUF4161); Region: DUF4161; pfam13722
519441003975	Carbon starvation protein, predicted membrane protein [Signal transduction mechanisms]; Region: CstA; COG1966
519441003976	Carbon starvation protein CstA; Region: CstA; pfam02554
519441003977	Carbon starvation protein, predicted membrane protein [Signal transduction mechanisms]; Region: CstA; COG1966
519441003978	C-terminal domain on CstA (DUF4161); Region: DUF4161; pfam13722
519441003979	Phosphomannose isomerase [Carbohydrate transport and metabolism]; Region: ManA; COG1482
519441003980	Alpha-Mannosidase Binding Domain of Atg19/34; Region: ABD; cl15429
519441003981	Nucleotidyltransferase/DNA polymerase involved in DNA repair [DNA replication, recombination, and repair]; Region: DinP; COG0389
519441003982	Y-family of DNA polymerases; Region: PolY; cl12025
519441003983	active site
519441003984	DNA binding site [nucleotide binding]
519441003985	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
519441003986	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
519441003987	DNA-binding site [nucleotide binding]; DNA binding site
519441003988	UTRA domain; Region: UTRA; pfam07702
519441003989	threonine dehydratase; Provisional; Region: PRK08198
519441003990	Threonine dehydratase: The first step in amino acid degradation is the removal of nitrogen. Although the nitrogen atoms of most amino acids are transferred to alpha-ketoglutarate before removal, the alpha-amino group of threonine can be directly...; Region: Thr-dehyd; cd01562
519441003991	tetramer interface [polypeptide binding]; other site
519441003992	pyridoxal 5'-phosphate binding site [chemical binding]; other site
519441003993	catalytic residue [active]
519441003994	C-terminal ACT domain of biodegradative (catabolic) threonine dehydratase II (ThrD-II) and other related ACT domains; Region: ACT_ThrD-II-like; cd04886
519441003995	YadA-like, left-handed beta-roll; Region: LbR_YadA-like; cd12820
519441003996	trimer interface [polypeptide binding]; other site
519441003997	YadA-like, left-handed beta-roll; Region: LbR_YadA-like; cd12820
519441003998	trimer interface [polypeptide binding]; other site
519441003999	Haemagglutinin; Region: HIM; pfam05662
519441004000	YadA-like C-terminal region; Region: YadA; pfam03895
519441004001	Methionine Aminopeptidase 1. E.C. 3.4.11.18. Also known as methionyl aminopeptidase and Peptidase M. Catalyzes release of N-terminal amino acids, preferentially methionine, from peptides and arylamides; Region: MetAP1; cd01086
519441004002	active site
519441004003	Protein of unknown function (DUF2424); Region: DUF2424; pfam10340
519441004004	alpha/beta hydrolase fold; Region: Abhydrolase_3; pfam07859
519441004005	YadA-like, left-handed beta-roll; Region: LbR_YadA-like; cd12820
519441004006	trimer interface [polypeptide binding]; other site
519441004007	Left-handed beta-roll, including virulence factors and various other proteins; Region: LbR-like; cl17507
519441004008	trimer interface [polypeptide binding]; other site
519441004009	Haemagglutinin; Region: HIM; pfam05662
519441004010	YadA-like C-terminal region; Region: YadA; pfam03895
519441004011	Alpha amylase catalytic domain found in bacterial Alpha-amylases (also called 1,4-alpha-D-glucan-4-glucanohydrolase); Region: AmyAc_bac2_AmyA; cd11316
519441004012	Glycosidases [Carbohydrate transport and metabolism]; Region: AmyA; COG0366
519441004013	Ca binding site [ion binding]; other site
519441004014	active site
519441004015	catalytic site [active]
519441004016	Methionine Aminopeptidase 1. E.C. 3.4.11.18. Also known as methionyl aminopeptidase and Peptidase M. Catalyzes release of N-terminal amino acids, preferentially methionine, from peptides and arylamides; Region: MetAP1; cd01086
519441004017	active site
519441004018	adenylate kinase; Reviewed; Region: adk; PRK00279
519441004019	Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine triphosphates (ATP) to adenosine monophosphates (AMP) and to yield adenosine diphosphates (ADP). This enzyme is required for the biosynthesis of ADP and is essential for...; Region: ADK; cd01428
519441004020	AMP-binding site [chemical binding]; other site
519441004021	ATP-AMP (Ap5A)-binding site [chemical binding]; other site
519441004022	alpha/beta hydrolase fold; Region: Abhydrolase_3; pfam07859
519441004023	Protein of unknown function (DUF2424); Region: DUF2424; pfam10340
519441004024	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
519441004025	Helix-turn-helix domain; Region: HTH_28; pfam13518
519441004026	Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities [Amino acid transport and metabolism]; Region: MalY; COG1168
519441004027	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
519441004028	pyridoxal 5'-phosphate binding site [chemical binding]; other site
519441004029	homodimer interface [polypeptide binding]; other site
519441004030	catalytic residue [active]
519441004031	Phosphotransferase system, fructose-specific IIC component [Carbohydrate transport and metabolism]; Region: FruA; COG1299
519441004032	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
519441004033	active site
519441004034	P-loop; other site
519441004035	phosphorylation site [posttranslational modification]
519441004036	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2; Region: PTS_EIIA_2; pfam00359
519441004037	active site
519441004038	phosphorylation site [posttranslational modification]
519441004039	Transcriptional antiterminator [Transcription]; Region: BglG; COG3711
519441004040	Mga helix-turn-helix domain; Region: Mga; pfam05043
519441004041	PRD domain; Region: PRD; pfam00874
519441004042	PTS_IIB_bgl_like: the PTS (phosphotransferase system) IIB domain of a family of sensory systems composed of a membrane-bound sugar-sensor (similar to BglF) and a transcription antiterminator (similar to BglG) which regulate expression of genes involved...; Region: PTS_IIB_bgl_like; cd05568
519441004043	active site
519441004044	P-loop; other site
519441004045	phosphorylation site [posttranslational modification]
519441004046	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
519441004047	active site
519441004048	phosphorylation site [posttranslational modification]
519441004049	Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase [Carbohydrate transport and metabolism]; Region: BglB; COG2723
519441004050	beta-galactosidase; Region: BGL; TIGR03356
519441004051	PTS system, beta-glucoside-specific IIABC component; Region: PTS-II-ABC-beta; TIGR01995
519441004052	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
519441004053	active site turn [active]
519441004054	phosphorylation site [posttranslational modification]
519441004055	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
519441004056	Phosphotransferase system IIA components [Carbohydrate transport and metabolism]; Region: NagE; COG2190
519441004057	HPr interaction site; other site
519441004058	glycerol kinase (GK) interaction site [polypeptide binding]; other site
519441004059	active site
519441004060	phosphorylation site [posttranslational modification]
519441004061	CAT RNA binding domain; Region: CAT_RBD; smart01061
519441004062	PRD domain; Region: PRD; pfam00874
519441004063	chaperone protein DnaJ; Region: DnaJ_bact; TIGR02349
519441004064	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
519441004065	HSP70 interaction site [polypeptide binding]; other site
519441004066	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cl03262
519441004067	substrate binding site [polypeptide binding]; other site
519441004068	Zinc finger domain of DnaJ and HSP40; Region: DnaJ_zf; cd10719
519441004069	Zn binding sites [ion binding]; other site
519441004070	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cd10747
519441004071	dimer interface [polypeptide binding]; other site
519441004072	Aldose 1-epimerase, similar to Lactococcus lactis lacX; Region: Aldose_epim_lacX; cd09024
519441004073	active site
519441004074	catalytic residues [active]
519441004075	molecular chaperone DnaK; Provisional; Region: dnaK; PRK00290
519441004076	Nucleotide-binding domain of human HSPA9 and similar proteins; Region: HSPA9-Ssq1-like_NBD; cd10234
519441004077	nucleotide binding site [chemical binding]; other site
519441004078	NEF interaction site [polypeptide binding]; other site
519441004079	SBD interface [polypeptide binding]; other site
519441004080	GrpE; Region: GrpE; pfam01025
519441004081	GrpE is the adenine nucleotide exchange factor of DnaK (Hsp70)-type ATPases. The GrpE dimer binds to the ATPase domain of Hsp70 catalyzing the dissociation of ADP, which enables rebinding of ATP, one step in the Hsp70 reaction cycle in protein folding; Region: GrpE; cd00446
519441004082	dimer interface [polypeptide binding]; other site
519441004083	hsp70 (ATPase domain) interactions [polypeptide binding]; other site
519441004084	heat-inducible transcription repressor; Provisional; Region: hrcA; PRK00082
519441004085	Winged helix-turn-helix transcription repressor, HrcA DNA-binding; Region: HrcA_DNA-bdg; pfam03444
519441004086	ATP-dependent chaperone ClpB; Region: chaperone_ClpB; TIGR03346
519441004087	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
519441004088	Walker A motif; other site
519441004089	ATP binding site [chemical binding]; other site
519441004090	Walker B motif; other site
519441004091	arginine finger; other site
519441004092	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
519441004093	Walker A motif; other site
519441004094	ATP binding site [chemical binding]; other site
519441004095	Walker B motif; other site
519441004096	arginine finger; other site
519441004097	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431
519441004098	Protein of unknown function (DUF1706); Region: DUF1706; pfam08020
519441004099	16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases [Translation, ribosomal structure and biogenesis]; Region: RsuA; COG1187
519441004100	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
519441004101	RNA binding surface [nucleotide binding]; other site
519441004102	Pseudouridine synthases, RsuA subfamily; Region: PseudoU_synth_RsuA_like; cd02870
519441004103	active site
519441004104	Putative transcriptional regulators (Ypuh-like); Region: DUF387; pfam04079
519441004105	rod shape-determining protein MreB; Provisional; Region: PRK13930
519441004106	MreB and similar proteins; Region: MreB_like; cd10225
519441004107	nucleotide binding site [chemical binding]; other site
519441004108	Mg binding site [ion binding]; other site
519441004109	putative protofilament interaction site [polypeptide binding]; other site
519441004110	RodZ interaction site [polypeptide binding]; other site
519441004111	DNA segregation ATPase FtsK/SpoIIIE and related proteins [Cell division and chromosome partitioning]; Region: FtsK; COG1674
519441004112	FtsK/SpoIIIE family; Region: FtsK_SpoIIIE; pfam01580
519441004113	This domain directs oriented DNA translocation and forms a winged helix structure; Region: Ftsk_gamma; smart00843
519441004114	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
519441004115	catalytic core [active]
519441004116	UGMP family protein; Validated; Region: PRK09604
519441004117	tRNA threonylcarbamoyl adenosine modification protein YeaZ; Region: T6A_YeaZ; TIGR03725
519441004118	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
519441004119	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3330
519441004120	alpha/beta hydrolase fold; Region: Abhydrolase_3; pfam07859
519441004121	Protein of unknown function (DUF2424); Region: DUF2424; pfam10340
519441004122	alpha/beta hydrolase fold; Region: Abhydrolase_3; pfam07859
519441004123	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
519441004124	S-adenosylmethionine binding site [chemical binding]; other site
519441004125	Predicted methyltransferase regulatory domain; Region: MethyTransf_Reg; pfam10119
519441004126	Predicted regulatory domain of a methyltransferase [General function prediction only]; Region: COG4797
519441004127	phosphoglucomutase-2-like protein; Provisional; Region: PTZ00150
519441004128	This CD includes PGM2 (phosphoglucomutase 2) and PGM2L1 (phosphoglucomutase 2-like 1). The mammalian PGM2 is thought to be a phosphopentomutase that catalyzes the conversion of the nucleoside breakdown products, ribose-1-phosphate and...; Region: PGM2; cd05799
519441004129	active site
519441004130	substrate binding site [chemical binding]; other site
519441004131	metal binding site [ion binding]; metal-binding site
519441004132	Peptidase family M23; Region: Peptidase_M23; pfam01551
519441004133	Cell division protein [Cell division and chromosome partitioning]; Region: FtsX; COG2177
519441004134	Transketolase, C-terminal subunit [Carbohydrate transport and metabolism]; Region: COG3958
519441004135	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
519441004136	PYR/PP interface [polypeptide binding]; other site
519441004137	dimer interface [polypeptide binding]; other site
519441004138	TPP binding site [chemical binding]; other site
519441004139	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
519441004140	transketolase; Reviewed; Region: PRK05899
519441004141	Thiamine pyrophosphate (TPP) family, Transketolase (TK) subfamily, TPP-binding module; TK catalyzes the transfer of a two-carbon unit from ketose phosphates to aldose phosphates. In heterotrophic organisms, TK provides a link between glycolysis and the...; Region: TPP_TK; cd02012
519441004142	TPP-binding site [chemical binding]; other site
519441004143	dimer interface [polypeptide binding]; other site
519441004144	Na+/melibiose symporter and related transporters [Carbohydrate transport and metabolism]; Region: MelB; COG2211
519441004145	melibiose:sodium symporter; Provisional; Region: PRK10429; cl15392
519441004146	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
519441004147	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
519441004148	active site
519441004149	phosphorylation site [posttranslational modification]
519441004150	intermolecular recognition site; other site
519441004151	dimerization interface [polypeptide binding]; other site
519441004152	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
519441004153	DNA binding residues [nucleotide binding]
519441004154	dimerization interface [polypeptide binding]; other site
519441004155	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: COG4585
519441004156	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
519441004157	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
519441004158	Walker A/P-loop; other site
519441004159	ATP binding site [chemical binding]; other site
519441004160	Q-loop/lid; other site
519441004161	ABC transporter signature motif; other site
519441004162	Walker B; other site
519441004163	D-loop; other site
519441004164	H-loop/switch region; other site
519441004165	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
519441004166	Walker A/P-loop; other site
519441004167	alpha/beta hydrolase fold; Region: Abhydrolase_1; pfam00561
519441004168	hypothetical protein; Provisional; Region: PRK13670
519441004169	HIGH Nucleotidyl Transferase; Region: HIGH_NTase1; cl17673
519441004170	NADH:flavin oxidoreductases, Old Yellow Enzyme family [Energy production and conversion]; Region: NemA; COG1902
519441004171	TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl17186
519441004172	phosphate binding site [ion binding]; other site
519441004173	N-terminal Early set domain, a glycogen binding domain, associated with the catalytic domain of AMP-activated protein kinase beta subunit; Region: E_set_AMPKbeta_like_N; cd02859
519441004174	glycogen binding site [chemical binding]; other site
519441004175	N-terminal Early set domain associated with the catalytic domain of cyclomaltodextrinase and pullulan-degrading enzymes; Region: E_set_CDase_PDE_N; cd02857
519441004176	homodimer interface [polypeptide binding]; other site
519441004177	Alpha amylase catalytic domain family; Region: AmyAc_family; cl07893
519441004178	Alpha amylase catalytic domain family; Region: AmyAc_family; cl07893
519441004179	active site
519441004180	catalytic site [active]
519441004181	Alpha amylase, C-terminal all-beta domain; Region: Alpha-amylase_C; cl02706
519441004182	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
519441004183	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
519441004184	Walker A/P-loop; other site
519441004185	ATP binding site [chemical binding]; other site
519441004186	ABC transporter; Region: ABC_tran; pfam00005
519441004187	Q-loop/lid; other site
519441004188	ABC transporter signature motif; other site
519441004189	Walker B; other site
519441004190	D-loop; other site
519441004191	H-loop/switch region; other site
519441004192	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
519441004193	ATP-binding cassette domain of multidrug resistance protein-like transporters; Region: ABCC_MRP_Like; cd03228
519441004194	Walker A/P-loop; other site
519441004195	ATP binding site [chemical binding]; other site
519441004196	Q-loop/lid; other site
519441004197	ABC transporter signature motif; other site
519441004198	Walker B; other site
519441004199	D-loop; other site
519441004200	H-loop/switch region; other site
519441004201	Phosphotransferase system, galactitol-specific IIC component [Carbohydrate transport and metabolism]; Region: GatC; COG3775
519441004202	PTS system sugar-specific permease component; Region: EIIC-GAT; cl04451
519441004203	Predicted hydrolases of the HAD superfamily [General function prediction only]; Region: Cof; COG0561
519441004204	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
519441004205	active site
519441004206	motif I; other site
519441004207	motif II; other site
519441004208	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
519441004209	proline iminopeptidase, Neisseria-type subfamily; Region: pro_imino_pep_1; TIGR01249
519441004210	alpha/beta hydrolase fold; Region: Abhydrolase_3; pfam07859
519441004211	Cadmium resistance transporter; Region: Cad; pfam03596
519441004212	Helix-hairpin-helix motif; Region: HHH_3; pfam12836
519441004213	coproporphyrinogen III oxidase; Provisional; Region: PRK08207
519441004214	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
519441004215	FeS/SAM binding site; other site
519441004216	undecaprenyl pyrophosphate phosphatase; Reviewed; Region: PRK00281
519441004217	Left-handed beta-roll, including virulence factors and various other proteins; Region: LbR-like; cl17507
519441004218	trimer interface [polypeptide binding]; other site
519441004219	YadA-like, left-handed beta-roll; Region: LbR_YadA-like; cd12820
519441004220	trimer interface [polypeptide binding]; other site
519441004221	YadA-like, left-handed beta-roll; Region: LbR_YadA-like; cd12820
519441004222	trimer interface [polypeptide binding]; other site
519441004223	Haemagglutinin; Region: HIM; pfam05662
519441004224	YadA-like C-terminal region; Region: YadA; pfam03895
519441004225	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
519441004226	ligand binding site [chemical binding]; other site
519441004227	cardiolipin synthase; Region: bac_cardiolipin; TIGR04265
519441004228	Putative catalytic domain, repeat 1, of Streptococcus mutans uncharacterized protein SMU_988 and similar proteins; Region: PLDc_SMU_988_like_1; cd09154
519441004229	putative active site [active]
519441004230	catalytic site [active]
519441004231	Putative catalytic domain, repeat 2, of Streptococcus mutans uncharacterized protein SMU_988 and similar proteins; Region: PLDc_SMU_988_like_2; cd09160
519441004232	putative active site [active]
519441004233	catalytic site [active]
519441004234	Domain of unknown function DUF87; Region: DUF87; pfam01935
519441004235	HerA helicase [Replication, recombination, and repair]; Region: COG0433
519441004236	SIR2-like domain; Region: SIR2_2; pfam13289
519441004237	DEAD-like helicases superfamily; Region: DEXDc; smart00487
519441004238	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
519441004239	ATP binding site [chemical binding]; other site
519441004240	putative Mg++ binding site [ion binding]; other site
519441004241	head completion protein; Provisional; Region: 4; PHA02552
519441004242	Adenine specific DNA methylase Mod [DNA replication, recombination, and repair]; Region: COG2189
519441004243	DNA methylase; Region: N6_N4_Mtase; pfam01555
519441004244	DNA methylase; Region: N6_N4_Mtase; cl17433
519441004245	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
519441004246	non-specific DNA binding site [nucleotide binding]; other site
519441004247	salt bridge; other site
519441004248	sequence-specific DNA binding site [nucleotide binding]; other site
519441004249	GMP synthase; Reviewed; Region: guaA; PRK00074
519441004250	Type 1 glutamine amidotransferase (GATase1) domain found in GMP synthetase; Region: GATase1_GMP_Synthase; cd01742
519441004251	AMP/PPi binding site [chemical binding]; other site
519441004252	candidate oxyanion hole; other site
519441004253	catalytic triad [active]
519441004254	potential glutamine specificity residues [chemical binding]; other site
519441004255	The C-terminal domain of GMP synthetase. It contains two subdomains; the ATP pyrophosphatase domain which closes to the N-termial and the dimerization domain at C-terminal end. The ATP-PPase is a twisted, five-stranded parallel beta-sheet sandwiched...; Region: GMP_synthase_C; cd01997
519441004256	ATP Binding subdomain [chemical binding]; other site
519441004257	Ligand Binding sites [chemical binding]; other site
519441004258	Dimerization subdomain; other site
519441004259	Serine phosphatase RsbU, regulator of sigma subunit [Signal transduction mechanisms / Transcription]; Region: RsbU; COG2208
519441004260	Stage II sporulation protein E (SpoIIE); Region: SpoIIE; pfam07228
519441004261	TlpA-like family; composed of  TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a...; Region: TlpA_like_family; cd02966
519441004262	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
519441004263	catalytic residues [active]
519441004264	Cytochrome c biogenesis protein [Posttranslational modification, protein turnover, chaperones]; Region: CcdA; COG0785
519441004265	Cytochrome C biogenesis protein transmembrane region; Region: DsbD; pfam02683
519441004266	MutT homolog-1 (MTH1) is a member of the Nudix hydrolase superfamily. MTH1, the mammalian counterpart of MutT, hydrolyzes oxidized purine nucleoside triphosphates, such as 8-oxo-dGTP and 2-hydroxy-ATP, to monophosphates, thereby preventing the...; Region: MTH1; cd03427
519441004267	putative active site [active]
519441004268	nucleotide binding site [chemical binding]; other site
519441004269	nudix motif; other site
519441004270	putative metal binding site [ion binding]; other site
519441004271	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
519441004272	dimerization domain swap beta strand [polypeptide binding]; other site
519441004273	regulatory protein interface [polypeptide binding]; other site
519441004274	active site
519441004275	regulatory phosphorylation site [posttranslational modification]; other site
519441004276	30S ribosomal protein S1; Reviewed; Region: rpsA; PRK06299
519441004277	S1_RPS1_repeat_ec1_hs1: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture...; Region: S1_RPS1_repeat_ec1_hs1; cd05687
519441004278	RNA binding site [nucleotide binding]; other site
519441004279	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
519441004280	RNA binding site [nucleotide binding]; other site
519441004281	Ribosomal protein S1-like RNA-binding domain; Region: S1; smart00316
519441004282	RNA binding site [nucleotide binding]; other site
519441004283	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cd00164
519441004284	RNA binding site [nucleotide binding]; other site
519441004285	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
519441004286	RNA binding site [nucleotide binding]; other site
519441004287	Predicted kinase related to dihydroxyacetone kinase [General function prediction only]; Region: COG1461
519441004288	DAK2 domain; Region: Dak2; pfam02734
519441004289	EDD domain protein, DegV family; Region: DegV; TIGR00762
519441004290	Uncharacterized protein, DegV family COG1307; Region: DegV; pfam02645
519441004291	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
519441004292	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
519441004293	active site
519441004294	Co/Zn/Cd efflux system component [Inorganic ion transport and metabolism]; Region: CzcD; COG1230
519441004295	Predicted Co/Zn/Cd cation transporters [Inorganic ion transport and metabolism]; Region: MMT1; COG0053
519441004296	Caseinolytic protease (ClpP) is an ATP-dependent protease; Region: Clp_protease_like; cl15763
519441004297	active site
519441004298	Signal peptide peptidase A (SppA), a serine protease, has catalytic Ser-Lys dyad; Region: S49_Sppa_N_C; cd07023
519441004299	tandem repeat interface [polypeptide binding]; other site
519441004300	signal peptide peptidase SppA, 36K type; Region: SppA_dom; TIGR00706
519441004301	oligomer interface [polypeptide binding]; other site
519441004302	active site residues [active]
519441004303	Predicted membrane protein [Function unknown]; Region: COG4709
519441004304	N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains) [Cell envelope biogenesis, outer membrane]; Region: GlmU; COG1207
519441004305	N-terminal domain of bacterial GlmU; Region: GT2_GlmU_N_bac; cd02540
519441004306	Substrate binding site; other site
519441004307	Mg++ binding site; other site
519441004308	N-acetyl-glucosamine-1-phosphate uridyltransferase (GlmU), C-terminal left-handed beta-helix (LbH) acetyltransferase domain: GlmU is also known as UDP-N-acetylglucosamine pyrophosphorylase. It is a bifunctional bacterial enzyme that catalyzes two...; Region: LbH_GlmU_C; cd03353
519441004309	active site
519441004310	substrate binding site [chemical binding]; other site
519441004311	CoA binding site [chemical binding]; other site
519441004312	ribose-phosphate pyrophosphokinase; Provisional; Region: PRK01259
519441004313	N-terminal domain of ribose phosphate pyrophosphokinase; Region: Pribosyltran_N; pfam13793
519441004314	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
519441004315	active site
519441004316	Putative translation factor (SUA5) [Translation, ribosomal structure and biogenesis]; Region: SUA5; COG0009
519441004317	Type II/IV secretion system protein; Region: T2SE; pfam00437
519441004318	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
519441004319	Walker A motif; other site
519441004320	ATP binding site [chemical binding]; other site
519441004321	Walker B motif; other site
519441004322	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
519441004323	tRNA pseudouridine synthase A; Validated; Region: truA; PRK00021
519441004324	Eukaryotic and bacterial pseudouridine synthases similar to E.  coli TruA; Region: PseudoU_synth_EcTruA; cd02570
519441004325	dimerization interface 3.5A [polypeptide binding]; other site
519441004326	active site
519441004327	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
519441004328	haloacid dehalogenase-like hydrolase; Region: Hydrolase_3; pfam08282
519441004329	active site
519441004330	motif I; other site
519441004331	motif II; other site
519441004332	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
519441004333	ribosomal protein S16; Region: S16; TIGR00002
519441004334	O-succinylbenzoic acid--CoA ligase; Provisional; Region: PRK03640
519441004335	Long-chain fatty acid CoA synthetases and Bubblegum-like very long-chain fatty acid CoA synthetases; Region: VL_LC_FACS_like; cd05907
519441004336	acyl-activating enzyme (AAE) consensus motif; other site
519441004337	putative AMP binding site [chemical binding]; other site
519441004338	putative active site [active]
519441004339	putative CoA binding site [chemical binding]; other site
519441004340	Acyl carrier protein [Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism]; Region: AcpP; COG0236
519441004341	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989
519441004342	1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid metabolism]; Region: PlsC; COG0204
519441004343	putative acyl-acceptor binding pocket; other site
519441004344	Long-chain acyl-CoA synthetases (AMP-forming) [Lipid metabolism]; Region: FAA1; COG1022
519441004345	Long-chain fatty acid CoA synthetases and Bubblegum-like very long-chain fatty acid CoA synthetases; Region: VL_LC_FACS_like; cd05907
519441004346	acyl-activating enzyme (AAE) consensus motif; other site
519441004347	putative AMP binding site [chemical binding]; other site
519441004348	putative active site [active]
519441004349	putative CoA binding site [chemical binding]; other site
519441004350	Domain of unknown function (DUF4009); Region: DUF4009; pfam13193
519441004351	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
519441004352	1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid metabolism]; Region: PlsC; COG0204
519441004353	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989
519441004354	putative acyl-acceptor binding pocket; other site
519441004355	signal recognition particle protein; Provisional; Region: PRK10867
519441004356	SRP54-type protein, helical bundle domain; Region: SRP54_N; smart00963
519441004357	The signal recognition particle (SRP) mediates the transport to or across the plasma membrane in bacteria and the endoplasmic reticulum in eukaryotes. SRP recognizes N-terminal sighnal sequences of newly synthesized polypeptides at the ribosome. The...; Region: SRP; cd03115
519441004358	P loop; other site
519441004359	GTP binding site [chemical binding]; other site
519441004360	Signal peptide binding domain; Region: SRP_SPB; pfam02978
519441004361	putative DNA-binding protein; Validated; Region: PRK00118
519441004362	Eco57I restriction-modification methylase; Region: Eco57I; pfam07669
519441004363	Eco57I restriction-modification methylase; Region: Eco57I; pfam07669
519441004364	CAAX protease self-immunity; Region: Abi; pfam02517
519441004365	A new structural DNA glycosylase; Region: AlkD_like; cd06561
519441004366	active site
519441004367	Branched-chain amino acid transport protein; Region: Branch_AA_trans; cl00547
519441004368	The substrate-binding component of an uncharacterized ABC-type nickel/dipeptide/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like_19; cd08518
519441004369	Bacterial extracellular solute-binding proteins, family 5 Middle; Region: SBP_bac_5; pfam00496
519441004370	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
519441004371	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
519441004372	dimer interface [polypeptide binding]; other site
519441004373	conserved gate region; other site
519441004374	putative PBP binding loops; other site
519441004375	ABC-ATPase subunit interface; other site
519441004376	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppC; COG1173
519441004377	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
519441004378	dimer interface [polypeptide binding]; other site
519441004379	conserved gate region; other site
519441004380	putative PBP binding loops; other site
519441004381	ABC-ATPase subunit interface; other site
519441004382	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppF; COG1124
519441004383	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
519441004384	Walker A/P-loop; other site
519441004385	ATP binding site [chemical binding]; other site
519441004386	Q-loop/lid; other site
519441004387	ABC transporter signature motif; other site
519441004388	Walker B; other site
519441004389	D-loop; other site
519441004390	H-loop/switch region; other site
519441004391	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
519441004392	ABC-type cobalt transport system, ATPase component [Inorganic ion transport and metabolism]; Region: CbiO; COG1122
519441004393	Walker A/P-loop; other site
519441004394	ATP binding site [chemical binding]; other site
519441004395	Q-loop/lid; other site
519441004396	ABC transporter signature motif; other site
519441004397	Walker B; other site
519441004398	D-loop; other site
519441004399	H-loop/switch region; other site
519441004400	transcription antitermination protein NusB; Reviewed; Region: nusB; PRK00202
519441004401	putative RNA binding site [nucleotide binding]; other site
519441004402	Asp23 family; Region: Asp23; pfam03780
519441004403	DNA polymerase III, alpha subunit [DNA replication, recombination, and repair]; Region: DnaE; COG0587
519441004404	Polymerase and Histidinol Phosphatase domain; Region: PHP; cl17102
519441004405	active site
519441004406	DnaE_OBF: A subfamily of OB folds corresponding to the C-terminal OB-fold nucleic acid binding domain of Thermus aquaticus and Escherichia coli type C replicative DNA polymerase III alpha subunit (DnaE). The DNA polymerase holoenzyme of E. coli contains...; Region: DnaE_OBF; cd04485
519441004407	generic binding surface I; other site
519441004408	Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes [Amino acid transport and metabolism]; Region: NifS; COG1104
519441004409	cysteine desulfurase NifS; Region: FeS_nifS; TIGR03402
519441004410	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
519441004411	catalytic residue [active]
519441004412	Protein of unknown function (DUF1294); Region: DUF1294; pfam06961
519441004413	30S ribosomal protein S18; Reviewed; Region: rpsR; PRK00391
519441004414	Single-stranded DNA-binding protein [DNA replication, recombination, and repair]; Region: Ssb; COG0629
519441004415	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
519441004416	dimer interface [polypeptide binding]; other site
519441004417	ssDNA binding site [nucleotide binding]; other site
519441004418	tetramer (dimer of dimers) interface [polypeptide binding]; other site
519441004419	30S ribosomal protein S6; Reviewed; Region: rpsF; PRK00453
519441004420	YadA-like, left-handed beta-roll; Region: LbR_YadA-like; cd12820
519441004421	trimer interface [polypeptide binding]; other site
519441004422	Haemagglutinin; Region: HIM; pfam05662
519441004423	YadA-like C-terminal region; Region: YadA; pfam03895
519441004424	YadA-like, left-handed beta-roll; Region: LbR_YadA-like; cd12820
519441004425	trimer interface [polypeptide binding]; other site
519441004426	Haemagglutinin; Region: HIM; pfam05662
519441004427	YadA-like, left-handed beta-roll; Region: LbR_YadA-like; cd12820
519441004428	trimer interface [polypeptide binding]; other site
519441004429	YadA-like, left-handed beta-roll; Region: LbR_YadA-like; cd12820
519441004430	trimer interface [polypeptide binding]; other site
519441004431	YadA-like, left-handed beta-roll; Region: LbR_YadA-like; cd12820
519441004432	trimer interface [polypeptide binding]; other site
519441004433	YadA-like C-terminal region; Region: YadA; pfam03895
519441004434	YadA-like, left-handed beta-roll; Region: LbR_YadA-like; cd12820
519441004435	trimer interface [polypeptide binding]; other site
519441004436	YadA-like C-terminal region; Region: YadA; pfam03895
519441004437	YadA-like, left-handed beta-roll; Region: LbR_YadA-like; cd12820
519441004438	trimer interface [polypeptide binding]; other site
519441004439	Haemagglutinin; Region: HIM; pfam05662
519441004440	Left-handed beta-roll, including virulence factors and various other proteins; Region: LbR-like; cl17507
519441004441	trimer interface [polypeptide binding]; other site
519441004442	Haemagglutinin; Region: HIM; pfam05662
519441004443	YadA-like C-terminal region; Region: YadA; pfam03895
519441004444	Left-handed beta-roll, including virulence factors and various other proteins; Region: LbR-like; cl17507
519441004445	trimer interface [polypeptide binding]; other site
519441004446	YadA-like, left-handed beta-roll; Region: LbR_YadA-like; cd12820
519441004447	trimer interface [polypeptide binding]; other site
519441004448	YadA-like, left-handed beta-roll; Region: LbR_YadA-like; cd12820
519441004449	trimer interface [polypeptide binding]; other site
519441004450	Left-handed beta-roll, including virulence factors and various other proteins; Region: LbR-like; cl17507
519441004451	trimer interface [polypeptide binding]; other site
519441004452	Haemagglutinin; Region: HIM; pfam05662
519441004453	YadA-like C-terminal region; Region: YadA; pfam03895
519441004454	Peptidase propeptide and YPEB domain; Region: PepSY; pfam03413
519441004455	Peptidase propeptide and YPEB domain; Region: PepSY; pfam03413
519441004456	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
519441004457	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
519441004458	active site
519441004459	phosphorylation site [posttranslational modification]
519441004460	intermolecular recognition site; other site
519441004461	dimerization interface [polypeptide binding]; other site
519441004462	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
519441004463	DNA binding site [nucleotide binding]
519441004464	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
519441004465	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
519441004466	dimerization interface [polypeptide binding]; other site
519441004467	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
519441004468	dimer interface [polypeptide binding]; other site
519441004469	phosphorylation site [posttranslational modification]
519441004470	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
519441004471	ATP binding site [chemical binding]; other site
519441004472	Mg2+ binding site [ion binding]; other site
519441004473	G-X-G motif; other site
519441004474	putative ATPase RIL; Provisional; Region: PRK13409
519441004475	Uncharacterized proteins with similarity to Ribonucleotide reductase and Pyruvate formate lyase; Region: RNR_PFL_like_DUF711; cd08025
519441004476	ACT domain proteins similar to the yet uncharacterized Streptococcus pneumoniae ACT domain protein; Region: ACT_1ZPV; cd04872
519441004477	multifunctional aminopeptidase A; Provisional; Region: PRK00913
519441004478	Cytosol aminopeptidase family, N-terminal and catalytic domains.  Family M17 contains zinc- and manganese-dependent exopeptidases ( EC  3.4.11.1), including leucine aminopeptidase. They catalyze removal of amino acids from the N-terminus of a protein and...; Region: Peptidase_M17; cd00433
519441004479	interface (dimer of trimers) [polypeptide binding]; other site
519441004480	Substrate-binding/catalytic site; other site
519441004481	Zn-binding sites [ion binding]; other site
519441004482	Na+/Pi-cotransporter; Region: Na_Pi_cotrans; pfam02690
519441004483	Na+/phosphate symporter [Inorganic ion transport and metabolism]; Region: NptA; COG1283
519441004484	Na+/Pi-cotransporter; Region: Na_Pi_cotrans; pfam02690
519441004485	PhoU domain; Region: PhoU; pfam01895
519441004486	PhoU domain; Region: PhoU; pfam01895
519441004487	Peptidyl-tRNA hydrolase (PTH) is a monomeric protein that cleaves the ester bond linking the nascent peptide and tRNA when peptidyl-tRNA is released prematurely from the ribosome. This ensures the recycling of peptidyl-tRNAs into tRNAs produced through...; Region: PTH; cd00462
519441004488	putative active site [active]
519441004489	catalytic residue [active]
519441004490	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
519441004491	Coenzyme A binding pocket [chemical binding]; other site
519441004492	ABC-2 family transporter protein; Region: ABC2_membrane_6; cl01496
519441004493	ABC-type uncharacterized transport system, permease component [General function prediction only]; Region: COG4587
519441004494	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
519441004495	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
519441004496	Walker A/P-loop; other site
519441004497	ATP binding site [chemical binding]; other site
519441004498	Q-loop/lid; other site
519441004499	ABC transporter signature motif; other site
519441004500	Walker B; other site
519441004501	D-loop; other site
519441004502	H-loop/switch region; other site
519441004503	TPR repeat; Region: TPR_11; pfam13414
519441004504	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
519441004505	binding surface
519441004506	TPR motif; other site
519441004507	Family A polymerase primarily fills DNA gaps that arise during DNA repair, recombination and replication; Region: DNA_pol_A; cl02626