-- dump date 20140620_081034 -- class Genbank::CDS -- table cds -- table main -- field 1 id -- field 2 GI -- field 3 GeneID -- field 4 chrom_position -- field 5 chromosome -- field 6 codon_start -- field 7 contig -- field 8 description -- field 9 end_pos -- field 10 gene -- field 11 gene_id -- field 12 name -- field 13 organism -- field 14 product -- field 15 protein_id -- field 16 start_pos -- field 17 strand -- field 18 taxid -- field 19 type -- header -- id GI GeneID chrom_position chromosome codon_start contig description end_pos gene gene_id name organism product protein_id start_pos strand taxid type NP_687037.1 22536186 1012723 102..1463 1 NC_004116.1 binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication; can also affect transcription of multiple genes including itself.; chromosome replication initiator DnaA 1463 dnaA 1012723 dnaA Streptococcus agalactiae 2603V/R chromosome replication initiator DnaA NP_687037.1 102 D 208435 CDS NP_687038.1 22536187 1012719 1618..2754 1 NC_004116.1 binds the polymerase to DNA and acts as a sliding clamp; DNA polymerase III subunit beta 2754 dnaN 1012719 dnaN Streptococcus agalactiae 2603V/R DNA polymerase III subunit beta NP_687038.1 1618 D 208435 CDS NP_687039.1 22536188 1012720 2824..3705 1 NC_004116.1 identified by match to PFAM protein family HMM PF00781; diacylglycerol kinase catalytic subunit 3705 1012720 SAG0003 Streptococcus agalactiae 2603V/R diacylglycerol kinase catalytic subunit NP_687039.1 2824 D 208435 CDS NP_687040.1 22536189 1012721 3715..3912 1 NC_004116.1 hypothetical protein 3912 1012721 SAG0004 Streptococcus agalactiae 2603V/R hypothetical protein NP_687040.1 3715 D 208435 CDS NP_687041.1 22536190 1012722 4114..4317 1 NC_004116.1 hypothetical protein 4317 1012722 SAG0005 Streptococcus agalactiae 2603V/R hypothetical protein NP_687041.1 4114 D 208435 CDS NP_687042.1 22536191 1012724 4477..5592 1 NC_004116.1 translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1; GTP-dependent nucleic acid-binding protein EngD 5592 ychF 1012724 ychF Streptococcus agalactiae 2603V/R GTP-dependent nucleic acid-binding protein EngD NP_687042.1 4477 D 208435 CDS NP_687043.1 22536192 1012725 5676..6251 1 NC_004116.1 Enables the recycling of peptidyl-tRNAs produced at termination of translation; peptidyl-tRNA hydrolase 6251 pth 1012725 pth Streptococcus agalactiae 2603V/R peptidyl-tRNA hydrolase NP_687043.1 5676 D 208435 CDS NP_687044.1 22536193 1012726 6248..9745 1 NC_004116.1 identified by match to PFAM protein family HMM PF00270; transcription-repair coupling factor 9745 mfd 1012726 mfd Streptococcus agalactiae 2603V/R transcription-repair coupling factor NP_687044.1 6248 D 208435 CDS NP_687045.1 22536194 1012727 9906..10001 1 NC_004116.1 hypothetical protein 10001 1012727 SAG0009 Streptococcus agalactiae 2603V/R hypothetical protein NP_687045.1 9906 D 208435 CDS NP_687046.1 22536195 1012728 10036..10308 1 NC_004116.1 identified by match to PFAM protein family HMM PF01479; S4 domain-containing protein 10308 1012728 SAG0010 Streptococcus agalactiae 2603V/R S4 domain-containing protein NP_687046.1 10036 D 208435 CDS NP_687047.1 22536196 1012729 10295..10666 1 NC_004116.1 similar to OMNI:NTL01SPL0011; identified by sequence similarity; hypothetical protein 10666 1012729 SAG0011 Streptococcus agalactiae 2603V/R hypothetical protein NP_687047.1 10295 D 208435 CDS NP_687048.1 22536197 1012730 10669..10803 1 NC_004116.1 hypothetical protein 10803 1012730 SAG0012 Streptococcus agalactiae 2603V/R hypothetical protein NP_687048.1 10669 D 208435 CDS NP_687049.1 22536198 1012731 10803..12089 1 NC_004116.1 The product of this gene was detected by Western blot analysis. For details on the method see Tettelin et al. 2002.; hypothetical protein 12089 1012731 SAG0013 Streptococcus agalactiae 2603V/R hypothetical protein NP_687049.1 10803 D 208435 CDS NP_687050.1 22536199 1012732 12091..13365 1 NC_004116.1 MesJ/Ycf62 family protein 13365 1012732 SAG0014 Streptococcus agalactiae 2603V/R MesJ/Ycf62 family protein NP_687050.1 12091 D 208435 CDS NP_687051.1 22536200 1012733 13370..13912 1 NC_004116.1 Catalyzes the salvage synthesis of inosine-5'-monophosphate (IMP) and guanosine-5'-monophosphate (GMP) from the purine bases hypoxanthine and guanine, respectively; hypoxanthine-guanine phosphoribosyltransferase 13912 hpt 1012733 hpt Streptococcus agalactiae 2603V/R hypoxanthine-guanine phosphoribosyltransferase NP_687051.1 13370 D 208435 CDS NP_687052.1 22536201 1012734 13935..15911 1 NC_004116.1 identified by match to PFAM protein family HMM PF00004; cell division protein FtsH 15911 ftsH 1012734 ftsH Streptococcus agalactiae 2603V/R cell division protein FtsH NP_687052.1 13935 D 208435 CDS NP_687053.1 22536202 1012767 28902..30245 1 NC_004116.1 similar to GP:12667037; identified by sequence similarity; PcsB protein 30245 pscB 1012767 pscB Streptococcus agalactiae 2603V/R PcsB protein NP_687053.1 28902 D 208435 CDS NP_687054.1 22536203 1012768 30369..31337 1 NC_004116.1 catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP; ribose-phosphate pyrophosphokinase 31337 prsA-1 1012768 prsA-1 Streptococcus agalactiae 2603V/R ribose-phosphate pyrophosphokinase NP_687054.1 30369 D 208435 CDS NP_687055.1 22536204 1012769 31445..32620 1 NC_004116.1 catalyzes the transamination of the aromatic amino acid forming a ketoacid; first step in aromatic amino acid degradation in lactococci; aromatic amino acid aminotransferase 32620 1012769 SAG0019 Streptococcus agalactiae 2603V/R aromatic amino acid aminotransferase NP_687055.1 31445 D 208435 CDS NP_687056.1 22536205 1012770 32610..33371 1 NC_004116.1 involved in DNA repair and RecFOR pathway recombination; RecFOR proteins displace ssDNA-binding protein and facilitate the production of RecA-coated ssDNA; DNA repair protein RecO 33371 recO 1012770 recO Streptococcus agalactiae 2603V/R DNA repair protein RecO NP_687056.1 32610 D 208435 CDS NP_687057.1 22536206 1012771 33461..34312 1 NC_004116.1 identified by match to PFAM protein family HMM PF02517; protease 34312 1012771 SAG0021 Streptococcus agalactiae 2603V/R protease NP_687057.1 33461 D 208435 CDS NP_687058.1 22536207 1012772 34390..35382 1 NC_004116.1 involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsY; glycerol-3-phosphate acyltransferase PlsX 35382 plsX 1012772 plsX Streptococcus agalactiae 2603V/R glycerol-3-phosphate acyltransferase PlsX NP_687058.1 34390 D 208435 CDS NP_687059.1 22536208 1012773 35393..35632 1 NC_004116.1 carries the fatty acid chain in fatty acid biosynthesis; acyl carrier protein 35632 acpP-1 1012773 acpP-1 Streptococcus agalactiae 2603V/R acyl carrier protein NP_687059.1 35393 D 208435 CDS NP_687060.1 22536209 1012774 35756..36460 1 NC_004116.1 catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis; SAICAR synthase; phosphoribosylaminoimidazole-succinocarboxamide synthase 36460 purC 1012774 purC Streptococcus agalactiae 2603V/R phosphoribosylaminoimidazole-succinocarboxamide synthase NP_687060.1 35756 D 208435 CDS NP_687061.1 22536210 1012775 36583..40308 1 NC_004116.1 identified by match to PFAM protein family HMM PF02769; phosphoribosylformylglycinamidine synthase 40308 1012775 SAG0025 Streptococcus agalactiae 2603V/R phosphoribosylformylglycinamidine synthase NP_687061.1 36583 D 208435 CDS NP_687062.1 22536211 1012776 40720..42174 1 NC_004116.1 Catalyzes first step of the de novo purine nucleotide biosynthetic pathway; amidophosphoribosyltransferase 42174 purF 1012776 purF Streptococcus agalactiae 2603V/R amidophosphoribosyltransferase NP_687062.1 40720 D 208435 CDS NP_687063.1 22536212 1012777 42202..43224 1 NC_004116.1 catalyzes the formation of 1-(5-phosphoribosyl)-5-aminoimidazole from 2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in purine biosynthesis; phosphoribosylaminoimidazole synthetase 43224 purM 1012777 purM Streptococcus agalactiae 2603V/R phosphoribosylaminoimidazole synthetase NP_687063.1 42202 D 208435 CDS NP_687064.1 22536213 1012778 43392..43940 1 NC_004116.1 glycinamide ribonucleotide transformylase; GAR Tfase; catalyzes the synthesis of 5'-phosphoribosylformylglycinamide from 5'-phosphoribosylglycinamide and 10-formyltetrahydrofolate; PurN requires formyl folate for the reaction unlike PurT which uses formate; phosphoribosylglycinamide formyltransferase 43940 purN 1012778 purN Streptococcus agalactiae 2603V/R phosphoribosylglycinamide formyltransferase NP_687064.1 43392 D 208435 CDS NP_687065.1 22536214 1012779 43963..44715 1 NC_004116.1 identified by match to PFAM protein family HMM PF00583; acetyltransferase 44715 1012779 SAG0029 Streptococcus agalactiae 2603V/R acetyltransferase NP_687065.1 43963 D 208435 CDS NP_687066.1 22536215 1012780 44735..46282 1 NC_004116.1 involved in de novo purine biosynthesis; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 46282 purH 1012780 purH Streptococcus agalactiae 2603V/R bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase NP_687066.1 44735 D 208435 CDS NP_687067.1 22536216 1012781 46475..47374 1 NC_004116.1 identified by match to PFAM protein family HMM PF01551; M24/M37 family peptidase 47374 1012781 SAG0031 Streptococcus agalactiae 2603V/R M24/M37 family peptidase NP_687067.1 46475 D 208435 CDS NP_687068.1 22536217 1012782 47521..48825 1 NC_004116.1 identified by match to PFAM protein family HMM PF01476; group B streptococcal surface immunogenic protein 48825 1012782 SAG0032 Streptococcus agalactiae 2603V/R group B streptococcal surface immunogenic protein NP_687068.1 47521 D 208435 CDS NP_687069.1 22536218 1012783 49072..49770 1 NC_004116.1 Converts N-acetylmannosamine-6-phosphate to N-acetylglucosamine-6-phosphate; N-acetylmannosamine-6-phosphate 2-epimerase 49770 1012783 SAG0033 Streptococcus agalactiae 2603V/R N-acetylmannosamine-6-phosphate 2-epimerase NP_687069.1 49072 D 208435 CDS NP_687070.1 22536219 1012784 49817..51133 1 NC_004116.1 identified by match to PFAM protein family HMM PF01547; sugar ABC transporter sugar-binding protein 51133 1012784 SAG0034 Streptococcus agalactiae 2603V/R sugar ABC transporter sugar-binding protein NP_687070.1 49817 D 208435 CDS NP_687071.1 22536220 1012785 51221..52108 1 NC_004116.1 identified by match to PFAM protein family HMM PF00528; sugar ABC transporter permease 52108 1012785 SAG0035 Streptococcus agalactiae 2603V/R sugar ABC transporter permease NP_687071.1 51221 D 208435 CDS NP_687072.1 22536221 1012786 52118..52948 1 NC_004116.1 identified by match to PFAM protein family HMM PF00528; sugar ABC transporter permease 52948 1012786 SAG0036 Streptococcus agalactiae 2603V/R sugar ABC transporter permease NP_687072.1 52118 D 208435 CDS NP_687073.1 22536222 1012787 52961..53404 1 NC_004116.1 hypothetical protein 53404 1012787 SAG0037 Streptococcus agalactiae 2603V/R hypothetical protein NP_687073.1 52961 D 208435 CDS NP_687074.1 22536223 1012788 53424..54086 1 NC_004116.1 hypothetical protein 54086 1012788 SAG0038 Streptococcus agalactiae 2603V/R hypothetical protein NP_687074.1 53424 D 208435 CDS NP_687075.1 22536224 1012789 54083..55000 1 NC_004116.1 identified by match to PFAM protein family HMM PF00701; N-acetylneuraminate lyase 55000 1012789 SAG0039 Streptococcus agalactiae 2603V/R N-acetylneuraminate lyase NP_687075.1 54083 D 208435 CDS NP_687076.1 22536225 1012790 55017..55898 1 NC_004116.1 identified by match to PFAM protein family HMM PF00480; The product of this gene was detected by Western blot analysis. For details on the method see Tettelin et al. 2002.; ROK family protein 55898 1012790 SAG0040 Streptococcus agalactiae 2603V/R ROK family protein NP_687076.1 55017 D 208435 CDS NP_687077.1 22536226 1012791 55906..56883 1 NC_004116.1 acetyl xylan esterase 56883 1012791 SAG0041 Streptococcus agalactiae 2603V/R acetyl xylan esterase NP_687077.1 55906 D 208435 CDS NP_687078.1 22536227 1012792 complement(56906..57709) 1 NC_004116.1 identified by match to PFAM protein family HMM PF01380; RpiR family transcriptional regulator 57709 1012792 SAG0042 Streptococcus agalactiae 2603V/R RpiR family transcriptional regulator NP_687078.1 56906 R 208435 CDS NP_687079.1 22536228 1012793 57991..59256 1 NC_004116.1 catalyzes the formation of N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-D-ribosylamine and glycine in purine biosynthesis; phosphoribosylamine--glycine ligase 59256 purD 1012793 purD Streptococcus agalactiae 2603V/R phosphoribosylamine--glycine ligase NP_687079.1 57991 D 208435 CDS NP_687080.1 22536229 1012794 59537..60025 1 NC_004116.1 Catalyzes a step in the de novo purine nucleotide biosynthetic pathway; phosphoribosylaminoimidazole carboxylase catalytic subunit 60025 purE 1012794 purE Streptococcus agalactiae 2603V/R phosphoribosylaminoimidazole carboxylase catalytic subunit NP_687080.1 59537 D 208435 CDS NP_687081.1 22536230 1012795 60012..61103 1 NC_004116.1 With PurE catalyzes the conversion of aminoimidazole ribonucleotide to carboxyaminoimidazole ribonucleotide in the de novo purine nucleotide biosynthetic pathway; phosphoribosylaminoimidazole carboxylase ATPase subunit 61103 purK 1012795 purK Streptococcus agalactiae 2603V/R phosphoribosylaminoimidazole carboxylase ATPase subunit NP_687081.1 60012 D 208435 CDS NP_687082.1 22536231 1012796 61157..62548 1 NC_004116.1 hypothetical protein 62548 1012796 SAG0046 Streptococcus agalactiae 2603V/R hypothetical protein NP_687082.1 61157 D 208435 CDS NP_687083.1 22536232 1012797 62573..63871 1 NC_004116.1 Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide; adenylosuccinate lyase 63871 purB 1012797 purB Streptococcus agalactiae 2603V/R adenylosuccinate lyase NP_687083.1 62573 D 208435 CDS NP_687084.1 22536233 1012798 64023..64934 1 NC_004116.1 identified by match to PFAM protein family HMM PF01381; Cro/CI family transcriptional regulator 64934 1012798 SAG0048 Streptococcus agalactiae 2603V/R Cro/CI family transcriptional regulator NP_687084.1 64023 D 208435 CDS NP_687085.1 22536234 1012799 65231..66229 1 NC_004116.1 promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration; Holliday junction DNA helicase RuvB 66229 ruvB 1012799 ruvB Streptococcus agalactiae 2603V/R Holliday junction DNA helicase RuvB NP_687085.1 65231 D 208435 CDS NP_687086.1 22536235 1012800 66381..66818 1 NC_004116.1 identified by match to PFAM protein family HMM PF01451; phosphotyrosine protein phosphatase, low molecular weight 66818 1012800 SAG0050 Streptococcus agalactiae 2603V/R phosphotyrosine protein phosphatase, low molecular weight NP_687086.1 66381 D 208435 CDS NP_687087.1 22536236 1012801 66825..67205 1 NC_004116.1 identified by match to PFAM protein family HMM PF02493; MORN motif-containing protein 67205 1012801 SAG0051 Streptococcus agalactiae 2603V/R MORN motif-containing protein NP_687087.1 66825 D 208435 CDS NP_687088.1 22536237 1012802 67202..68980 1 NC_004116.1 identified by match to PFAM protein family HMM PF01757; hypothetical protein 68980 1012802 SAG0052 Streptococcus agalactiae 2603V/R hypothetical protein NP_687088.1 67202 D 208435 CDS NP_687089.1 22536238 1012803 69250..71892 1 NC_004116.1 identified by match to PFAM protein family HMM PF00171; bifunctional acetaldehyde-CoA/alcohol dehydrogenase 71892 adhE 1012803 adhE Streptococcus agalactiae 2603V/R bifunctional acetaldehyde-CoA/alcohol dehydrogenase NP_687089.1 69250 D 208435 CDS NP_687090.1 22536239 1012804 72071..73087 1 NC_004116.1 similar to zinc-dependent eukaryotic ADH enzymes and distinct from fermentative ADHs; alcohol dehydrogenase 73087 adhP 1012804 adhP Streptococcus agalactiae 2603V/R alcohol dehydrogenase NP_687090.1 72071 D 208435 CDS NP_687091.1 22536240 1012805 73207..74697 1 NC_004116.1 catalyzes the formation of L-threonine from O-phospho-L-homoserine; threonine synthase 74697 thrC 1012805 thrC Streptococcus agalactiae 2603V/R threonine synthase NP_687091.1 73207 D 208435 CDS NP_687092.1 22536241 1012806 74844..76082 1 NC_004116.1 identified by match to PFAM protein family HMM PF01554; MATE efflux family protein 76082 1012806 SAG0056 Streptococcus agalactiae 2603V/R MATE efflux family protein NP_687092.1 74844 D 208435 CDS NP_687093.1 22536242 1012807 76288..76596 1 NC_004116.1 NusE; involved in assembly of the 30S subunit; in the ribosome, this protein is involved in the binding of tRNA; in Escherichia coli this protein was also found to be involved in transcription antitermination; NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination; binding of NusB/S10 to boxA nucleates assembly of the antitermination complex; 30S ribosomal protein S10 76596 rpsJ 1012807 rpsJ Streptococcus agalactiae 2603V/R 30S ribosomal protein S10 NP_687093.1 76288 D 208435 CDS NP_687094.1 22536243 1012808 76701..77327 1 NC_004116.1 binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin; 50S ribosomal protein L3 77327 rplC 1012808 rplC Streptococcus agalactiae 2603V/R 50S ribosomal protein L3 NP_687094.1 76701 D 208435 CDS NP_687095.1 22536244 1012809 77351..77974 1 NC_004116.1 L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA; 50S ribosomal protein L4 77974 rplD 1012809 rplD Streptococcus agalactiae 2603V/R 50S ribosomal protein L4 NP_687095.1 77351 D 208435 CDS NP_687096.1 22536245 1012810 77974..78270 1 NC_004116.1 binds third domain of 23S rRNA and protein L29; part of exit tunnel; 50S ribosomal protein L23 78270 rplW 1012810 rplW Streptococcus agalactiae 2603V/R 50S ribosomal protein L23 NP_687096.1 77974 D 208435 CDS NP_687097.1 22536246 1012811 78288..79121 1 NC_004116.1 one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation; 50S ribosomal protein L2 79121 rplB 1012811 rplB Streptococcus agalactiae 2603V/R 50S ribosomal protein L2 NP_687097.1 78288 D 208435 CDS NP_687098.1 22536247 1012812 79220..79498 1 NC_004116.1 protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA; 30S ribosomal protein S19 79498 rpsS 1012812 rpsS Streptococcus agalactiae 2603V/R 30S ribosomal protein S19 NP_687098.1 79220 D 208435 CDS NP_687099.1 22536248 1012813 79514..79858 1 NC_004116.1 binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center; 50S ribosomal protein L22 79858 rplV 1012813 rplV Streptococcus agalactiae 2603V/R 50S ribosomal protein L22 NP_687099.1 79514 D 208435 CDS NP_687100.1 22536249 1012814 79871..80524 1 NC_004116.1 forms a complex with S10 and S14; binds the lower part of the 30S subunit head and the mRNA in the complete ribosome to position it for translation; 30S ribosomal protein S3 80524 rpsC 1012814 rpsC Streptococcus agalactiae 2603V/R 30S ribosomal protein S3 NP_687100.1 79871 D 208435 CDS NP_687101.1 22536250 1012815 80528..80941 1 NC_004116.1 located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e; 50S ribosomal protein L16 80941 rplP 1012815 rplP Streptococcus agalactiae 2603V/R 50S ribosomal protein L16 NP_687101.1 80528 D 208435 CDS NP_687102.1 22536251 1012816 80951..81157 1 NC_004116.1 one of the stabilizing components for the large ribosomal subunit; 50S ribosomal protein L29 81157 rpmC 1012816 rpmC Streptococcus agalactiae 2603V/R 50S ribosomal protein L29 NP_687102.1 80951 D 208435 CDS NP_687103.1 22536252 1012817 81183..81443 1 NC_004116.1 primary binding protein; helps mediate assembly; involved in translation fidelity; 30S ribosomal protein S17 81443 rpsQ 1012817 rpsQ Streptococcus agalactiae 2603V/R 30S ribosomal protein S17 NP_687103.1 81183 D 208435 CDS NP_687104.1 22536253 1012818 81468..81836 1 NC_004116.1 binds to the 23S rRNA between the centers for peptidyl transferase and GTPase; 50S ribosomal protein L14 81836 rplN 1012818 rplN Streptococcus agalactiae 2603V/R 50S ribosomal protein L14 NP_687104.1 81468 D 208435 CDS NP_687105.1 22536254 1012819 81916..82221 1 NC_004116.1 assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel; 50S ribosomal protein L24 82221 rplX 1012819 rplX Streptococcus agalactiae 2603V/R 50S ribosomal protein L24 NP_687105.1 81916 D 208435 CDS NP_687106.1 22536255 1012820 82245..82787 1 NC_004116.1 part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13; 50S ribosomal protein L5 82787 rplE 1012820 rplE Streptococcus agalactiae 2603V/R 50S ribosomal protein L5 NP_687106.1 82245 D 208435 CDS NP_687107.1 22536256 1012821 82805..82990 1 NC_004116.1 located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group appear to contain the zinc-binding motif; 30S ribosomal protein S14 82990 rpsN 1012821 rpsN Streptococcus agalactiae 2603V/R 30S ribosomal protein S14 NP_687107.1 82805 D 208435 CDS NP_687108.1 22536257 1012822 83145..83543 1 NC_004116.1 binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; 30S ribosomal protein S8 83543 rpsH 1012822 rpsH Streptococcus agalactiae 2603V/R 30S ribosomal protein S8 NP_687108.1 83145 D 208435 CDS NP_687109.1 22536258 1012823 83653..84189 1 NC_004116.1 ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance; 50S ribosomal protein L6 84189 rplF 1012823 rplF Streptococcus agalactiae 2603V/R 50S ribosomal protein L6 NP_687109.1 83653 D 208435 CDS NP_687110.1 22536259 1012824 84290..84646 1 NC_004116.1 binds 5S rRNA along with protein L5 and L25; 50S ribosomal protein L18 84646 rplR 1012824 rplR Streptococcus agalactiae 2603V/R 50S ribosomal protein L18 NP_687110.1 84290 D 208435 CDS NP_687111.1 22536260 1012825 84665..85159 1 NC_004116.1 located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance; 30S ribosomal protein S5 85159 rpsE 1012825 rpsE Streptococcus agalactiae 2603V/R 30S ribosomal protein S5 NP_687111.1 84665 D 208435 CDS NP_687112.1 22536261 1012826 85174..85353 1 NC_004116.1 L30 binds domain II of the 23S rRNA and the 5S rRNA; similar to eukaryotic protein L7; 50S ribosomal protein L30 85353 rpmD 1012826 rpmD Streptococcus agalactiae 2603V/R 50S ribosomal protein L30 NP_687112.1 85174 D 208435 CDS NP_687113.1 22536262 1012827 85478..85918 1 NC_004116.1 late assembly protein; 50S ribosomal protein L15 85918 rplO 1012827 rplO Streptococcus agalactiae 2603V/R 50S ribosomal protein L15 NP_687113.1 85478 D 208435 CDS NP_687114.1 22536263 1012828 85939..87243 1 NC_004116.1 forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase; preprotein translocase subunit SecY 87243 secY 1012828 secY Streptococcus agalactiae 2603V/R preprotein translocase subunit SecY NP_687114.1 85939 D 208435 CDS NP_687115.1 22536264 1012829 87338..87976 1 NC_004116.1 essential enzyme that recycles AMP in active cells; converts ATP and AMP to two molecules of ADP; adenylate kinase 87976 adk 1012829 adk Streptococcus agalactiae 2603V/R adenylate kinase NP_687115.1 87338 D 208435 CDS NP_687116.1 22536265 1012830 88092..88310 1 NC_004116.1 stimulates the activities of the other two initiation factors, IF-2 and IF-3; translation initiation factor IF-1 88310 infA 1012830 infA Streptococcus agalactiae 2603V/R translation initiation factor IF-1 NP_687116.1 88092 D 208435 CDS NP_687117.1 22536266 1012831 88336..88452 1 NC_004116.1 smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group have the motif; 50S ribosomal protein L36 88452 rpmJ 1012831 rpmJ Streptococcus agalactiae 2603V/R 50S ribosomal protein L36 NP_687117.1 88336 D 208435 CDS NP_687118.1 22536267 1012832 88470..88835 1 NC_004116.1 located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA; 30S ribosomal protein S13 88835 rpsM 1012832 rpsM Streptococcus agalactiae 2603V/R 30S ribosomal protein S13 NP_687118.1 88470 D 208435 CDS NP_687119.2 161485618 1012833 88853..89236 1 NC_004116.1 located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3; 30S ribosomal protein S11 89236 rpsK 1012833 rpsK Streptococcus agalactiae 2603V/R 30S ribosomal protein S11 NP_687119.2 88853 D 208435 CDS NP_687120.1 22536269 1012834 89286..90224 1 NC_004116.1 catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme; DNA-directed RNA polymerase subunit alpha 90224 rpoA 1012834 rpoA Streptococcus agalactiae 2603V/R DNA-directed RNA polymerase subunit alpha NP_687120.1 89286 D 208435 CDS NP_687121.1 22536270 1012835 90239..90625 1 NC_004116.1 is a component of the macrolide binding site in the peptidyl transferase center; 50S ribosomal protein L17 90625 rplQ 1012835 rplQ Streptococcus agalactiae 2603V/R 50S ribosomal protein L17 NP_687121.1 90239 D 208435 CDS NP_687122.1 22536271 1012854 97819..98076 1 NC_004116.1 lipoprotein 98076 1012854 SAG0086 Streptococcus agalactiae 2603V/R lipoprotein NP_687122.1 97819 D 208435 CDS NP_687123.1 22536272 1012855 98067..98246 1 NC_004116.1 hypothetical protein 98246 1012855 SAG0087 Streptococcus agalactiae 2603V/R hypothetical protein NP_687123.1 98067 D 208435 CDS NP_687124.1 22536273 1012856 98316..98486 1 NC_004116.1 hypothetical protein 98486 1012856 SAG0088 Streptococcus agalactiae 2603V/R hypothetical protein NP_687124.1 98316 D 208435 CDS NP_687125.1 22536274 1012857 99401..99952 1 NC_004116.1 hypothetical protein 99952 1012857 SAG0089 Streptococcus agalactiae 2603V/R hypothetical protein NP_687125.1 99401 D 208435 CDS NP_687126.1 22536275 1012858 100172..100591 1 NC_004116.1 hypothetical protein 100591 1012858 SAG0090 Streptococcus agalactiae 2603V/R hypothetical protein NP_687126.1 100172 D 208435 CDS NP_687127.1 22536276 1012859 100836..101270 1 NC_004116.1 similar to OMNI:SP0014; identified by sequence similarity; ComX1 family transcriptional regulator 101270 1012859 SAG0091 Streptococcus agalactiae 2603V/R ComX1 family transcriptional regulator NP_687127.1 100836 D 208435 CDS NP_687128.1 22536277 1012860 101392..102084 1 NC_004116.1 identified by match to PFAM protein family HMM PF00300; phosphoglycerate mutase family protein 102084 1012860 SAG0092 Streptococcus agalactiae 2603V/R phosphoglycerate mutase family protein NP_687128.1 101392 D 208435 CDS NP_687129.1 22536278 1012861 102081..102833 1 NC_004116.1 identified by match to PFAM protein family HMM PF02557; D-alanyl-D-alanine carboxypeptidase 102833 1012861 SAG0093 Streptococcus agalactiae 2603V/R D-alanyl-D-alanine carboxypeptidase NP_687129.1 102081 D 208435 CDS NP_687130.1 22536279 1012862 102830..103405 1 NC_004116.1 identified by match to PFAM protein family HMM PF01832; N-acetylmuramoyl-L-alanine amidase 103405 1012862 SAG0094 Streptococcus agalactiae 2603V/R N-acetylmuramoyl-L-alanine amidase NP_687130.1 102830 D 208435 CDS NP_687131.1 22536280 1012863 103548..104582 1 NC_004116.1 Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons; heat-inducible transcription repressor 104582 hrcA 1012863 hrcA Streptococcus agalactiae 2603V/R heat-inducible transcription repressor NP_687131.1 103548 D 208435 CDS NP_687132.1 22536281 1012864 104585..105157 1 NC_004116.1 with DnaK and DnaJ acts in response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins; may act as a thermosensor; heat shock protein GrpE 105157 grpE 1012864 grpE Streptococcus agalactiae 2603V/R heat shock protein GrpE NP_687132.1 104585 D 208435 CDS NP_687133.1 22536282 1012865 105338..107167 1 NC_004116.1 heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria; molecular chaperone DnaK 107167 dnaK 1012865 dnaK Streptococcus agalactiae 2603V/R molecular chaperone DnaK NP_687133.1 105338 D 208435 CDS NP_687134.1 22536283 1012866 107456..108595 1 NC_004116.1 chaperone Hsp40; co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion; molecular chaperone DnaJ 108595 dnaJ 1012866 dnaJ Streptococcus agalactiae 2603V/R molecular chaperone DnaJ NP_687134.1 107456 D 208435 CDS NP_687135.1 22536284 1012867 108709..109956 1 NC_004116.1 identified by match to PFAM protein family HMM PF00392; GntR family transcriptional regulator 109956 1012867 SAG0099 Streptococcus agalactiae 2603V/R GntR family transcriptional regulator NP_687135.1 108709 D 208435 CDS NP_687136.1 22536285 1012868 110027..110803 1 NC_004116.1 mediates pseudouridylation (positions 38, 39, 40) at the tRNA anticodon region which contributes to the structural stability; tRNA pseudouridine synthase A 110803 truA 1012868 truA Streptococcus agalactiae 2603V/R tRNA pseudouridine synthase A NP_687136.1 110027 D 208435 CDS NP_687137.1 22536286 1012869 110766..111524 1 NC_004116.1 catalyzes the formation of 4-amino-2-methyl-5-diphosphomethylpyrimidine; phosphomethylpyrimidine kinase 111524 1012869 SAG0101 Streptococcus agalactiae 2603V/R phosphomethylpyrimidine kinase NP_687137.1 110766 D 208435 CDS NP_687138.1 22536287 1012870 111534..111998 1 NC_004116.1 hypothetical protein 111998 1012870 SAG0102 Streptococcus agalactiae 2603V/R hypothetical protein NP_687138.1 111534 D 208435 CDS NP_687139.1 22536288 1012871 111995..112564 1 NC_004116.1 hypothetical protein 112564 1012871 SAG0103 Streptococcus agalactiae 2603V/R hypothetical protein NP_687139.1 111995 D 208435 CDS NP_687140.1 22536289 1012872 complement(112601..113443) 1 NC_004116.1 hypothetical protein 113443 1012872 SAG0104 Streptococcus agalactiae 2603V/R hypothetical protein NP_687140.1 112601 R 208435 CDS NP_687141.1 22536290 1012873 113600..114883 1 NC_004116.1 Tig; RopA; peptidyl-prolyl cis/trans isomerase; promotes folding of newly synthesized proteins; binds ribosomal 50S subunit; forms a homodimer; trigger factor 114883 tig 1012873 tig Streptococcus agalactiae 2603V/R trigger factor NP_687141.1 113600 D 208435 CDS NP_687142.1 22536291 1012874 115072..115647 1 NC_004116.1 participates in both the initiation and recycling phases of transcription; in the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling; DNA-directed RNA polymerase subunit delta 115647 1012874 SAG0106 Streptococcus agalactiae 2603V/R DNA-directed RNA polymerase subunit delta NP_687142.1 115072 D 208435 CDS NP_687143.1 22536292 1012875 115920..117524 1 NC_004116.1 CTP synthase; CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer; CTP synthetase 117524 pyrG 1012875 pyrG Streptococcus agalactiae 2603V/R CTP synthetase NP_687143.1 115920 D 208435 CDS NP_687144.1 22536293 1012876 117633..118559 1 NC_004116.1 hypothetical protein 118559 1012876 SAG0108 Streptococcus agalactiae 2603V/R hypothetical protein NP_687144.1 117633 D 208435 CDS NP_687145.1 22536294 1012878 118754..119200 1 NC_004116.1 catalyzes the formation of dUMP from dUTP; deoxyuridine 5'-triphosphate nucleotidohydrolase 119200 dut 1012878 dut Streptococcus agalactiae 2603V/R deoxyuridine 5'-triphosphate nucleotidohydrolase NP_687145.1 118754 D 208435 CDS NP_687146.1 22536295 1012879 119362..120726 1 NC_004116.1 Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents; DNA repair protein RadA 120726 radA 1012879 radA Streptococcus agalactiae 2603V/R DNA repair protein RadA NP_687146.1 119362 D 208435 CDS NP_687147.1 22536296 1012880 120862..121359 1 NC_004116.1 carbonic anhydrase-like protein 121359 1012880 SAG0111 Streptococcus agalactiae 2603V/R carbonic anhydrase-like protein NP_687147.1 120862 D 208435 CDS NP_687148.1 22536297 1012881 121513..122832 1 NC_004116.1 Involved in disulfide oxidoreductase activity and electron transport; pyridine nucleotide-disulfide oxidoreductase 122832 1012881 SAG0112 Streptococcus agalactiae 2603V/R pyridine nucleotide-disulfide oxidoreductase NP_687148.1 121513 D 208435 CDS NP_687149.1 22536298 1012882 123041..124495 1 NC_004116.1 Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation; glutamyl-tRNA synthetase 124495 gltX 1012882 gltX Streptococcus agalactiae 2603V/R glutamyl-tRNA synthetase NP_687149.1 123041 D 208435 CDS NP_687150.1 22536299 1012883 complement(124535..125503) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00532; ribose ABC transporter periplasmic D-ribose-binding protein 125503 rbsB 1012883 rbsB Streptococcus agalactiae 2603V/R ribose ABC transporter periplasmic D-ribose-binding protein NP_687150.1 124535 R 208435 CDS NP_687151.1 22536300 1012884 complement(125556..126488) 1 NC_004116.1 identified by match to PFAM protein family HMM PF02653; ribose ABC transporter permease 126488 rbsC 1012884 rbsC Streptococcus agalactiae 2603V/R ribose ABC transporter permease NP_687151.1 125556 R 208435 CDS NP_687152.1 22536301 1012885 complement(126499..127977) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00005; ribose ABC transporter ATP-binding protein 127977 rbsA 1012885 rbsA Streptococcus agalactiae 2603V/R ribose ABC transporter ATP-binding protein NP_687152.1 126499 R 208435 CDS NP_687153.1 22536302 1012886 complement(127993..128391) 1 NC_004116.1 cytoplasmic mutarotase that catalyzes the conversion between beta-pyran and beta-furan forms of D-ribose; RbsD is required for efficient ribose utilization in E. coli; rbsD-mutant E. coli strains are unable to use ribose as a sole carbon source; D-ribose pyranase 128391 rbsD 1012886 rbsD Streptococcus agalactiae 2603V/R D-ribose pyranase NP_687153.1 127993 R 208435 CDS NP_687154.1 22536303 1012887 complement(128366..129277) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00294; ribokinase 129277 rbsK 1012887 rbsK Streptococcus agalactiae 2603V/R ribokinase NP_687154.1 128366 R 208435 CDS NP_687155.1 22536304 1012888 complement(129270..130256) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00356; ribose operon repressor RbsR 130256 rbsR 1012888 rbsR Streptococcus agalactiae 2603V/R ribose operon repressor RbsR NP_687155.1 129270 R 208435 CDS NP_687156.1 22536305 1012889 complement(130314..130412) 1 NC_004116.1 hypothetical protein 130412 1012889 SAG0120 Streptococcus agalactiae 2603V/R hypothetical protein NP_687156.1 130314 R 208435 CDS NP_687157.1 22536306 1012890 130438..131526 1 NC_004116.1 identified by match to PFAM protein family HMM PF02687; permease 131526 1012890 SAG0121 Streptococcus agalactiae 2603V/R permease NP_687157.1 130438 D 208435 CDS NP_687158.1 22536307 1012891 131526..132212 1 NC_004116.1 identified by match to PFAM protein family HMM PF00005; ABC transporter ATP-binding protein 132212 1012891 SAG0122 Streptococcus agalactiae 2603V/R ABC transporter ATP-binding protein NP_687158.1 131526 D 208435 CDS NP_687159.1 22536308 1012892 132243..132914 1 NC_004116.1 identified by match to PFAM protein family HMM PF00072; DNA-binding response regulator 132914 1012892 SAG0123 Streptococcus agalactiae 2603V/R DNA-binding response regulator NP_687159.1 132243 D 208435 CDS NP_687160.1 22536309 1012893 132907..133977 1 NC_004116.1 identified by match to PFAM protein family HMM PF00512; sensor histidine kinase 133977 1012893 SAG0124 Streptococcus agalactiae 2603V/R sensor histidine kinase NP_687160.1 132907 D 208435 CDS NP_687161.1 22536310 1012894 134131..135321 1 NC_004116.1 catalyzes the formation of 2-N(omega)-(L-arginino)succinate from L-citrulline and L-aspartate in arginine biosynthesis, AMP-forming; argininosuccinate synthase 135321 argG 1012894 argG Streptococcus agalactiae 2603V/R argininosuccinate synthase NP_687161.1 134131 D 208435 CDS NP_687162.1 22536311 1012895 135340..136728 1 NC_004116.1 catalyzes the formation of arginine from (N-L-arginino)succinate; argininosuccinate lyase 136728 argH 1012895 argH Streptococcus agalactiae 2603V/R argininosuccinate lyase NP_687162.1 135340 D 208435 CDS NP_687163.1 22536312 1012896 136869..137750 1 NC_004116.1 catalyzes the formation of glycerone phosphate and glyceraldehyde 3-phosphate from fructose 1,6, bisphosphate; fructose-bisphosphate aldolase 137750 fba 1012896 fba Streptococcus agalactiae 2603V/R fructose-bisphosphate aldolase NP_687163.1 136869 D 208435 CDS NP_687164.1 22536313 1012897 complement(137834..138751) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00056; L-2-hydroxyisocaproate dehydrogenase 138751 1012897 SAG0128 Streptococcus agalactiae 2603V/R L-2-hydroxyisocaproate dehydrogenase NP_687164.1 137834 R 208435 CDS NP_687165.1 22536314 1012898 138990..139178 1 NC_004116.1 required for 70S ribosome assembly; 50S ribosomal protein L28 139178 rpmB 1012898 rpmB Streptococcus agalactiae 2603V/R 50S ribosomal protein L28 NP_687165.1 138990 D 208435 CDS NP_687166.1 22536315 1012899 139310..139675 1 NC_004116.1 hypothetical protein 139675 1012899 SAG0130 Streptococcus agalactiae 2603V/R hypothetical protein NP_687166.1 139310 D 208435 CDS NP_687167.1 22536316 1012900 139708..141339 1 NC_004116.1 identified by match to PFAM protein family HMM PF02734; DAK2 domain-containing protein 141339 1012900 SAG0131 Streptococcus agalactiae 2603V/R DAK2 domain-containing protein NP_687167.1 139708 D 208435 CDS NP_687168.1 22536317 1012901 141487..142371 1 NC_004116.1 identified by match to PFAM protein family HMM PF01145; The product of this gene was detected by Western blot analysis. For details on the method see Tettelin et al. 2002.; hypothetical protein 142371 1012901 SAG0132 Streptococcus agalactiae 2603V/R hypothetical protein NP_687168.1 141487 D 208435 CDS NP_687169.1 22536318 1012902 complement(142463..142579) 1 NC_004116.1 hypothetical protein 142579 1012902 SAG0133 Streptococcus agalactiae 2603V/R hypothetical protein NP_687169.1 142463 R 208435 CDS NP_687170.1 22536319 1012903 complement(142947..143237) 1 NC_004116.1 hypothetical protein 143237 1012903 SAG0134 Streptococcus agalactiae 2603V/R hypothetical protein NP_687170.1 142947 R 208435 CDS NP_687171.1 22536320 1012904 complement(143579..144319) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00005; amino acid ABC transporter ATP-binding protein 144319 1012904 SAG0135 Streptococcus agalactiae 2603V/R amino acid ABC transporter ATP-binding protein NP_687171.1 143579 R 208435 CDS NP_687172.1 22536321 1012905 complement(144329..145879) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00497; amino acid ABC transporter amino acid-binding protein/permease 145879 1012905 SAG0136 Streptococcus agalactiae 2603V/R amino acid ABC transporter amino acid-binding protein/permease NP_687172.1 144329 R 208435 CDS NP_687173.1 22536322 1012906 146015..147898 1 NC_004116.1 hypothetical protein 147898 1012906 SAG0137 Streptococcus agalactiae 2603V/R hypothetical protein NP_687173.1 146015 D 208435 CDS NP_687174.1 22536323 1012907 147944..148783 1 NC_004116.1 BacA; phosphatase activity in Escherichia coli not kinase; involved in bacitracin resistance as bacitracin supposedly sequesters undecaprenyl disphosphate which reduces the pool of lipid carrier available to the cell; undecaprenyl pyrophosphate phosphatase 148783 uppP 1012907 uppP Streptococcus agalactiae 2603V/R undecaprenyl pyrophosphate phosphatase NP_687174.1 147944 D 208435 CDS NP_687175.1 22536324 1012908 148903..149658 1 NC_004116.1 enables recognition and targeting of proteins for proteolysis, involved in negative regulation of competence; adaptor protein 149658 1012908 SAG0139 Streptococcus agalactiae 2603V/R adaptor protein NP_687175.1 148903 D 208435 CDS NP_687176.1 22536325 1012909 149660..150820 1 NC_004116.1 identified by match to PFAM protein family HMM PF00953; glycoside hydrolase family protein 150820 1012909 SAG0140 Streptococcus agalactiae 2603V/R glycoside hydrolase family protein NP_687176.1 149660 D 208435 CDS NP_687177.1 22536326 1012910 150985..151755 1 NC_004116.1 identified by match to PFAM protein family HMM PF00005; ABC transporter ATP-binding protein 151755 1012910 SAG0141 Streptococcus agalactiae 2603V/R ABC transporter ATP-binding protein NP_687177.1 150985 D 208435 CDS NP_687178.1 22536327 1012911 151792..153054 1 NC_004116.1 hypothetical protein 153054 1012911 SAG0142 Streptococcus agalactiae 2603V/R hypothetical protein NP_687178.1 151792 D 208435 CDS NP_687179.1 22536328 1012912 153056..154288 1 NC_004116.1 identified by match to PFAM protein family HMM PF00266; selenocysteine lyase 154288 csdB 1012912 csdB Streptococcus agalactiae 2603V/R selenocysteine lyase NP_687179.1 153056 D 208435 CDS NP_687180.1 22536329 1012913 154275..154718 1 NC_004116.1 identified by match to PFAM protein family HMM PF01592; NifU family protein 154718 1012913 SAG0144 Streptococcus agalactiae 2603V/R NifU family protein NP_687180.1 154275 D 208435 CDS NP_687181.1 22536330 1012914 154818..156236 1 NC_004116.1 hypothetical protein 156236 1012914 SAG0145 Streptococcus agalactiae 2603V/R hypothetical protein NP_687181.1 154818 D 208435 CDS NP_687182.1 22536331 1012915 complement(156308..157495) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00768; penicillin-binding protein 4 157495 1012915 SAG0146 Streptococcus agalactiae 2603V/R penicillin-binding protein 4 NP_687182.1 156308 R 208435 CDS NP_687183.1 22536332 1012916 complement(157648..158883) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00768; D-alanyl-D-alanine carboxypeptidase 158883 1012916 SAG0147 Streptococcus agalactiae 2603V/R D-alanyl-D-alanine carboxypeptidase NP_687183.1 157648 R 208435 CDS NP_687184.1 22536333 1012917 159124..160779 1 NC_004116.1 identified by match to PFAM protein family HMM PF00496; oligopeptide ABC transporter substrate-binding protein 160779 1012917 SAG0148 Streptococcus agalactiae 2603V/R oligopeptide ABC transporter substrate-binding protein NP_687184.1 159124 D 208435 CDS NP_687185.1 22536334 1012918 160898..161812 1 NC_004116.1 identified by match to PFAM protein family HMM PF00528; oligopeptide ABC transporter permease 161812 1012918 SAG0149 Streptococcus agalactiae 2603V/R oligopeptide ABC transporter permease NP_687185.1 160898 D 208435 CDS NP_687186.1 22536335 1012919 161822..162853 1 NC_004116.1 identified by match to PFAM protein family HMM PF00528; oligopeptide ABC transporter permease 162853 1012919 SAG0150 Streptococcus agalactiae 2603V/R oligopeptide ABC transporter permease NP_687186.1 161822 D 208435 CDS NP_687187.1 22536336 1012920 162866..163912 1 NC_004116.1 identified by match to PFAM protein family HMM PF00005; oligopeptide ABC transporter ATP-binding protein 163912 1012920 SAG0151 Streptococcus agalactiae 2603V/R oligopeptide ABC transporter ATP-binding protein NP_687187.1 162866 D 208435 CDS NP_687188.1 22536337 1012921 163912..164844 1 NC_004116.1 identified by match to PFAM protein family HMM PF00005; oligopeptide ABC transporter ATP-binding protein 164844 1012921 SAG0152 Streptococcus agalactiae 2603V/R oligopeptide ABC transporter ATP-binding protein NP_687188.1 163912 D 208435 CDS NP_687189.1 22536338 1012927 170382..171233 1 NC_004116.1 An essential enzyme in the nonmevalonate pathway of isopentenyl diphosphate and dimethylallyl diphosphate biosynthesis; 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase 171233 ipk 1012927 ipk Streptococcus agalactiae 2603V/R 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase NP_687189.1 170382 D 208435 CDS NP_687190.1 22536339 1012928 171319..171762 1 NC_004116.1 identified by match to PFAM protein family HMM PF01047; adc operon repressor AdcR 171762 adcR 1012928 adcR Streptococcus agalactiae 2603V/R adc operon repressor AdcR NP_687190.1 171319 D 208435 CDS NP_687191.1 22536340 1012929 171765..172475 1 NC_004116.1 identified by match to PFAM protein family HMM PF00005; zinc ABC transporter ATP-binding protein 172475 1012929 SAG0155 Streptococcus agalactiae 2603V/R zinc ABC transporter ATP-binding protein NP_687191.1 171765 D 208435 CDS NP_687192.1 22536341 1012930 172465..173277 1 NC_004116.1 identified by match to PFAM protein family HMM PF00950; zinc ABC transporter permease 173277 1012930 SAG0156 Streptococcus agalactiae 2603V/R zinc ABC transporter permease NP_687192.1 172465 D 208435 CDS NP_687193.1 22536342 1012932 complement(175097..176356) 1 NC_004116.1 catalyzes the formation of tyrosyl-tRNA(Tyr) from tyrosine and tRNA(Tyr); tyrosyl-tRNA synthetase 176356 tyrS 1012932 tyrS Streptococcus agalactiae 2603V/R tyrosyl-tRNA synthetase NP_687193.1 175097 R 208435 CDS NP_687194.1 22536343 1012933 176467..178764 1 NC_004116.1 identified by match to PFAM protein family HMM PF00905; penicillin-binding protein 1B 178764 1012933 SAG0159 Streptococcus agalactiae 2603V/R penicillin-binding protein 1B NP_687194.1 176467 D 208435 CDS NP_687195.1 22536344 1012934 179288..182863 1 NC_004116.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme; DNA-directed RNA polymerase subunit beta 182863 rpoB 1012934 rpoB Streptococcus agalactiae 2603V/R DNA-directed RNA polymerase subunit beta NP_687195.1 179288 D 208435 CDS NP_687196.1 22536345 1012935 182980..186630 1 NC_004116.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Subunit beta' binds to sigma factor allowing it to bind to the -10 region of the promoter; DNA-directed RNA polymerase subunit beta' 186630 rpoC 1012935 rpoC Streptococcus agalactiae 2603V/R DNA-directed RNA polymerase subunit beta' NP_687196.1 182980 D 208435 CDS NP_687197.1 22536346 1012936 186744..187109 1 NC_004116.1 hypothetical protein 187109 1012936 SAG0162 Streptococcus agalactiae 2603V/R hypothetical protein NP_687197.1 186744 D 208435 CDS NP_687198.1 22536347 1012937 187282..188253 1 NC_004116.1 identified by match to PFAM protein family HMM PF00437; competence protein CglA 188253 cglA 1012937 cglA Streptococcus agalactiae 2603V/R competence protein CglA NP_687198.1 187282 D 208435 CDS NP_687199.1 22536348 1012938 188342..189190 1 NC_004116.1 identified by match to PFAM protein family HMM PF00482; competence protein CglB 189190 cglB 1012938 cglB Streptococcus agalactiae 2603V/R competence protein CglB NP_687199.1 188342 D 208435 CDS NP_687200.1 22536349 1012939 189187..189642 1 NC_004116.1 hypothetical protein 189642 1012939 SAG0165 Streptococcus agalactiae 2603V/R hypothetical protein NP_687200.1 189187 D 208435 CDS NP_687201.1 22536350 1012940 189620..189991 1 NC_004116.1 similar to OMNI:NTL01SPL0084; identified by sequence similarity; hypothetical protein 189991 1012940 SAG0166 Streptococcus agalactiae 2603V/R hypothetical protein NP_687201.1 189620 D 208435 CDS NP_687202.1 22536351 1012941 190106..191080 1 NC_004116.1 hypothetical protein 191080 1012941 SAG0167 Streptococcus agalactiae 2603V/R hypothetical protein NP_687202.1 190106 D 208435 CDS NP_687203.1 22536352 1012942 191112..192305 1 NC_004116.1 AckA utilizes acetate and can acetylate CheY which increases signal strength during flagellar rotation; utilizes magnesium and ATP; also involved in conversion of acetate to aceyl-CoA; acetate kinase 192305 ackA 1012942 ackA Streptococcus agalactiae 2603V/R acetate kinase NP_687203.1 191112 D 208435 CDS NP_687204.1 22536353 1012943 192457..192663 1 NC_004116.1 identified by match to PFAM protein family HMM PF01381; Cro/CI family transcriptional regulator 192663 1012943 SAG0169 Streptococcus agalactiae 2603V/R Cro/CI family transcriptional regulator NP_687204.1 192457 D 208435 CDS NP_687205.1 22536354 1012944 192722..192859 1 NC_004116.1 hypothetical protein 192859 1012944 SAG0170 Streptococcus agalactiae 2603V/R hypothetical protein NP_687205.1 192722 D 208435 CDS NP_687206.1 22536355 1012945 192900..193355 1 NC_004116.1 hypothetical protein 193355 1012945 SAG0171 Streptococcus agalactiae 2603V/R hypothetical protein NP_687206.1 192900 D 208435 CDS NP_687207.1 22536356 1012946 193424..194089 1 NC_004116.1 identified by match to PFAM protein family HMM PF02517; protease 194089 1012946 SAG0172 Streptococcus agalactiae 2603V/R protease NP_687207.1 193424 D 208435 CDS NP_687208.1 22536357 1012947 complement(194110..194880) 1 NC_004116.1 catalyzes the formation of L-proline from pyrroline-5-carboxylate; pyrroline-5-carboxylate reductase 194880 proC 1012947 proC Streptococcus agalactiae 2603V/R pyrroline-5-carboxylate reductase NP_687208.1 194110 R 208435 CDS NP_687209.1 22536358 1012948 complement(194950..196017) 1 NC_004116.1 similar to PID:1072381; identified by sequence similarity; glutamyl-aminopeptidase 196017 pepA 1012948 pepA Streptococcus agalactiae 2603V/R glutamyl-aminopeptidase NP_687209.1 194950 R 208435 CDS NP_687210.1 22536359 1012949 complement(196202..196441) 1 NC_004116.1 hypothetical protein 196441 1012949 SAG0175 Streptococcus agalactiae 2603V/R hypothetical protein NP_687210.1 196202 R 208435 CDS NP_687211.1 22536360 1012950 196602..196886 1 NC_004116.1 hypothetical protein 196886 1012950 SAG0176 Streptococcus agalactiae 2603V/R hypothetical protein NP_687211.1 196602 D 208435 CDS NP_687212.1 22536361 1012951 196883..197206 1 NC_004116.1 identified by match to PFAM protein family HMM PF00085; thioredoxin 197206 1012951 SAG0177 Streptococcus agalactiae 2603V/R thioredoxin NP_687212.1 196883 D 208435 CDS NP_687213.1 22536362 1012952 197239..197865 1 NC_004116.1 identified by match to PFAM protein family HMM PF01588; tRNA-binding domain-containing protein 197865 1012952 SAG0178 Streptococcus agalactiae 2603V/R tRNA-binding domain-containing protein NP_687213.1 197239 D 208435 CDS NP_687214.1 22536363 1012953 complement(197919..198635) 1 NC_004116.1 hypothetical protein 198635 1012953 SAG0179 Streptococcus agalactiae 2603V/R hypothetical protein NP_687214.1 197919 R 208435 CDS NP_687215.1 22536364 1012954 198716..199111 1 NC_004116.1 binds to single stranded DNA and may facilitate the binding and interaction of other proteins to DNA; single-stranded DNA-binding protein 199111 ssb-1 1012954 ssb-1 Streptococcus agalactiae 2603V/R single-stranded DNA-binding protein NP_687215.1 198716 D 208435 CDS NP_687216.1 22536365 1012955 199235..199879 1 NC_004116.1 identified by match to PFAM protein family HMM PF00702; HAD superfamily hydrolase 199879 1012955 SAG0181 Streptococcus agalactiae 2603V/R HAD superfamily hydrolase NP_687216.1 199235 D 208435 CDS NP_687217.1 22536366 1012956 199906..201651 1 NC_004116.1 identified by match to PFAM protein family HMM PF02518; sensor histidine kinase 201651 1012956 SAG0182 Streptococcus agalactiae 2603V/R sensor histidine kinase NP_687217.1 199906 D 208435 CDS NP_687218.1 22536367 1012957 201632..202372 1 NC_004116.1 identified by match to PFAM protein family HMM PF00072; response regulator 202372 1012957 SAG0183 Streptococcus agalactiae 2603V/R response regulator NP_687218.1 201632 D 208435 CDS NP_687219.1 22536368 1012958 202542..202997 1 NC_004116.1 hypothetical protein 202997 1012958 SAG0184 Streptococcus agalactiae 2603V/R hypothetical protein NP_687219.1 202542 D 208435 CDS NP_687220.1 22536369 1012959 202999..203727 1 NC_004116.1 hypothetical protein 203727 1012959 SAG0185 Streptococcus agalactiae 2603V/R hypothetical protein NP_687220.1 202999 D 208435 CDS NP_687221.1 22536370 1012960 complement(203839..203949) 1 NC_004116.1 hypothetical protein 203949 1012960 SAG0186 Streptococcus agalactiae 2603V/R hypothetical protein NP_687221.1 203839 R 208435 CDS NP_687222.1 22536371 1012961 203970..205598 1 NC_004116.1 identified by match to PFAM protein family HMM PF00496; oligopeptide ABC transporter oligopeptide-binding protein 205598 1012961 SAG0187 Streptococcus agalactiae 2603V/R oligopeptide ABC transporter oligopeptide-binding protein NP_687222.1 203970 D 208435 CDS NP_687223.1 22536372 1012962 205711..206688 1 NC_004116.1 identified by match to PFAM protein family HMM PF00528; oligopeptide ABC transporter permease 206688 1012962 SAG0188 Streptococcus agalactiae 2603V/R oligopeptide ABC transporter permease NP_687223.1 205711 D 208435 CDS NP_687224.1 22536373 1012963 206685..207506 1 NC_004116.1 identified by match to PFAM protein family HMM PF00528; oligopeptide ABC transporter permease 207506 1012963 SAG0189 Streptococcus agalactiae 2603V/R oligopeptide ABC transporter permease NP_687224.1 206685 D 208435 CDS NP_687225.1 22536374 1012964 207518..208321 1 NC_004116.1 identified by match to PFAM protein family HMM PF00005; peptide ABC transporter ATP-binding protein 208321 1012964 SAG0190 Streptococcus agalactiae 2603V/R peptide ABC transporter ATP-binding protein NP_687225.1 207518 D 208435 CDS NP_687226.1 22536375 1012965 208305..208931 1 NC_004116.1 identified by match to PFAM protein family HMM PF00005; peptide ABC transporter ATP-binding protein 208931 1012965 SAG0191 Streptococcus agalactiae 2603V/R peptide ABC transporter ATP-binding protein NP_687226.1 208305 D 208435 CDS NP_687227.1 22536376 1012966 209214..211244 1 NC_004116.1 identified by match to PFAM protein family HMM PF00358; PTS system transporter subunit IIABC 211244 1012966 SAG0192 Streptococcus agalactiae 2603V/R PTS system transporter subunit IIABC NP_687227.1 209214 D 208435 CDS NP_687228.1 22536377 1012967 211466..213091 1 NC_004116.1 identified by match to PFAM protein family HMM PF00128; alpha amylase 213091 1012967 SAG0193 Streptococcus agalactiae 2603V/R alpha amylase NP_687228.1 211466 D 208435 CDS NP_687229.1 22536378 1012968 213307..215226 1 NC_004116.1 identified by match to PFAM protein family HMM PF00359; BglG family transcriptional antiterminator 215226 1012968 SAG0194 Streptococcus agalactiae 2603V/R BglG family transcriptional antiterminator NP_687229.1 213307 D 208435 CDS NP_687230.1 22536379 1012969 complement(215240..216373) 1 NC_004116.1 identified by match to PFAM protein family HMM PF01609; IS1548 transposase 216373 1012969 SAG0195 Streptococcus agalactiae 2603V/R IS1548 transposase NP_687230.1 215240 R 208435 CDS NP_687231.1 22536380 1012970 216468..216668 1 NC_004116.1 similar to OMNI:SP2131; identified by sequence similarity; hypothetical protein 216668 1012970 SAG0196 Streptococcus agalactiae 2603V/R hypothetical protein NP_687231.1 216468 D 208435 CDS NP_687232.1 22536381 1012971 216671..216955 1 NC_004116.1 similar to OMNI:SP2130; identified by sequence similarity; PTS system transporter subunit IIB 216955 1012971 SAG0197 Streptococcus agalactiae 2603V/R PTS system transporter subunit IIB NP_687232.1 216671 D 208435 CDS NP_687233.1 22536382 1012972 216968..218323 1 NC_004116.1 membrane component; functions with enzymes IIB (sgaB; ulaB) and IIA (sgaA; ulaC) enzyme I and HPr for anaerobic utilization and uptake of L-ascorbate; sgaTBA are regulated by yifQ as well as Crp and Fnr; PTS system ascorbate-specific transporter subunit IIC 218323 ulaA 1012972 ulaA Streptococcus agalactiae 2603V/R PTS system ascorbate-specific transporter subunit IIC NP_687233.1 216968 D 208435 CDS NP_687234.1 22536383 1012973 218326..219183 1 NC_004116.1 identified by match to PFAM protein family HMM PF00456; transketolase 219183 1012973 SAG0199 Streptococcus agalactiae 2603V/R transketolase NP_687234.1 218326 D 208435 CDS NP_687235.1 22536384 1012974 219180..220109 1 NC_004116.1 identified by match to PFAM protein family HMM PF02779; transketolase 220109 1012974 SAG0200 Streptococcus agalactiae 2603V/R transketolase NP_687235.1 219180 D 208435 CDS NP_687236.1 22536385 1012975 220218..221477 1 NC_004116.1 identified by match to PFAM protein family HMM PF00175; oxidoreductase 221477 1012975 SAG0201 Streptococcus agalactiae 2603V/R oxidoreductase NP_687236.1 220218 D 208435 CDS NP_687237.1 22536386 1012976 221565..221834 1 NC_004116.1 primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence; 30S ribosomal protein S15 221834 rpsO 1012976 rpsO Streptococcus agalactiae 2603V/R 30S ribosomal protein S15 NP_687237.1 221565 D 208435 CDS NP_687238.1 22536387 1012977 222215..224344 1 NC_004116.1 identified by match to PFAM protein family HMM PF00013; polynucleotide phosphorylase 224344 pnp 1012977 pnp Streptococcus agalactiae 2603V/R polynucleotide phosphorylase NP_687238.1 222215 D 208435 CDS NP_687239.1 22536388 1012978 224346..225098 1 NC_004116.1 hypothetical protein 225098 1012978 SAG0204 Streptococcus agalactiae 2603V/R hypothetical protein NP_687239.1 224346 D 208435 CDS NP_687240.1 22536389 1012979 225107..225691 1 NC_004116.1 identified by match to PFAM protein family HMM PF00132; serine O-acetyltransferase 225691 cysE 1012979 cysE Streptococcus agalactiae 2603V/R serine O-acetyltransferase NP_687240.1 225107 D 208435 CDS NP_687241.1 22536390 1012980 225701..225883 1 NC_004116.1 lipoprotein 225883 1012980 SAG0206 Streptococcus agalactiae 2603V/R lipoprotein NP_687241.1 225701 D 208435 CDS NP_687242.1 22536391 1012981 225880..227223 1 NC_004116.1 catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA; cysteinyl-tRNA synthetase 227223 cysS 1012981 cysS Streptococcus agalactiae 2603V/R cysteinyl-tRNA synthetase NP_687242.1 225880 D 208435 CDS NP_687243.1 22536392 1012982 227216..227602 1 NC_004116.1 hypothetical protein 227602 1012982 SAG0208 Streptococcus agalactiae 2603V/R hypothetical protein NP_687243.1 227216 D 208435 CDS NP_687244.1 22536393 1012983 227705..228460 1 NC_004116.1 identified by match to PFAM protein family HMM PF00588; RNA methyltransferase 228460 1012983 SAG0209 Streptococcus agalactiae 2603V/R RNA methyltransferase NP_687244.1 227705 D 208435 CDS NP_687245.1 22536394 1012984 228457..228975 1 NC_004116.1 hypothetical protein 228975 1012984 SAG0210 Streptococcus agalactiae 2603V/R hypothetical protein NP_687245.1 228457 D 208435 CDS NP_687246.1 22536395 1012985 229068..229928 1 NC_004116.1 identified by match to PFAM protein family HMM PF02645; DegV family protein 229928 1012985 SAG0211 Streptococcus agalactiae 2603V/R DegV family protein NP_687246.1 229068 D 208435 CDS NP_687247.1 22536396 1012986 230061..230159 1 NC_004116.1 hypothetical protein 230159 1012986 SAG0212 Streptococcus agalactiae 2603V/R hypothetical protein NP_687247.1 230061 D 208435 CDS NP_687248.1 22536397 1012987 230273..230392 1 NC_004116.1 hypothetical protein 230392 1012987 SAG0213 Streptococcus agalactiae 2603V/R hypothetical protein NP_687248.1 230273 D 208435 CDS NP_687249.1 22536398 1012988 230809..231255 1 NC_004116.1 in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit; 50S ribosomal protein L13 231255 rplM 1012988 rplM Streptococcus agalactiae 2603V/R 50S ribosomal protein L13 NP_687249.1 230809 D 208435 CDS NP_687250.1 22536399 1012989 231276..231668 1 NC_004116.1 forms a direct contact with the tRNA during translation; 30S ribosomal protein S9 231668 rpsI 1012989 rpsI Streptococcus agalactiae 2603V/R 30S ribosomal protein S9 NP_687250.1 231276 D 208435 CDS NP_687251.1 22536400 1012990 complement(231682..231783) 1 NC_004116.1 hypothetical protein 231783 1012990 SAG0216 Streptococcus agalactiae 2603V/R hypothetical protein NP_687251.1 231682 R 208435 CDS NP_687252.1 22536401 1012991 complement(231796..232950) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00589; phage integrase family site specific recombinase 232950 1012991 SAG0217 Streptococcus agalactiae 2603V/R phage integrase family site specific recombinase NP_687252.1 231796 R 208435 CDS NP_687253.1 22536402 1012992 complement(233015..233491) 1 NC_004116.1 identified by match to PFAM protein family HMM PF01381; Cro/CI family transcriptional regulator 233491 1012992 SAG0218 Streptococcus agalactiae 2603V/R Cro/CI family transcriptional regulator NP_687253.1 233015 R 208435 CDS NP_687254.1 22536403 1012993 233645..233950 1 NC_004116.1 hypothetical protein 233950 1012993 SAG0219 Streptococcus agalactiae 2603V/R hypothetical protein NP_687254.1 233645 D 208435 CDS NP_687255.1 22536404 1012994 234087..234365 1 NC_004116.1 hypothetical protein 234365 1012994 SAG0220 Streptococcus agalactiae 2603V/R hypothetical protein NP_687255.1 234087 D 208435 CDS NP_687256.1 22536405 1012995 234376..234606 1 NC_004116.1 hypothetical protein 234606 1012995 SAG0221 Streptococcus agalactiae 2603V/R hypothetical protein NP_687256.1 234376 D 208435 CDS NP_687257.1 22536406 1012996 234619..234945 1 NC_004116.1 similar to OMNI:EFC0001; identified by sequence similarity; hypothetical protein 234945 1012996 SAG0222 Streptococcus agalactiae 2603V/R hypothetical protein NP_687257.1 234619 D 208435 CDS NP_687258.1 22536407 1012997 234949..235578 1 NC_004116.1 hypothetical protein 235578 1012997 SAG0223 Streptococcus agalactiae 2603V/R hypothetical protein NP_687258.1 234949 D 208435 CDS NP_687259.1 22536408 1012998 235768..236766 1 NC_004116.1 identified by match to PFAM protein family HMM PF02486; replication initiation protein 236766 1012998 SAG0224 Streptococcus agalactiae 2603V/R replication initiation protein NP_687259.1 235768 D 208435 CDS NP_687260.1 22536409 1012999 236802..237236 1 NC_004116.1 hypothetical protein 237236 1012999 SAG0225 Streptococcus agalactiae 2603V/R hypothetical protein NP_687260.1 236802 D 208435 CDS NP_687261.1 22536410 1013000 237552..238808 1 NC_004116.1 identified by match to PFAM protein family HMM PF01076; recombination protein 238808 1013000 SAG0226 Streptococcus agalactiae 2603V/R recombination protein NP_687261.1 237552 D 208435 CDS NP_687262.1 22536411 1013001 238976..239446 1 NC_004116.1 hypothetical protein 239446 1013001 SAG0227 Streptococcus agalactiae 2603V/R hypothetical protein NP_687262.1 238976 D 208435 CDS NP_687263.1 22536412 1013002 complement(239751..240086) 1 NC_004116.1 hypothetical protein 240086 1013002 SAG0228 Streptococcus agalactiae 2603V/R hypothetical protein NP_687263.1 239751 R 208435 CDS NP_687264.1 22536413 1013003 complement(240076..240363) 1 NC_004116.1 hypothetical protein 240363 1013003 SAG0229 Streptococcus agalactiae 2603V/R hypothetical protein NP_687264.1 240076 R 208435 CDS NP_687265.1 22536414 1013004 240870..241160 1 NC_004116.1 hypothetical protein 241160 1013004 SAG0230 Streptococcus agalactiae 2603V/R hypothetical protein NP_687265.1 240870 D 208435 CDS NP_687266.1 22536415 1013005 241262..241669 1 NC_004116.1 hypothetical protein 241669 1013005 SAG0231 Streptococcus agalactiae 2603V/R hypothetical protein NP_687266.1 241262 D 208435 CDS NP_687267.1 22536416 1013006 241669..242229 1 NC_004116.1 hypothetical protein 242229 1013006 SAG0232 Streptococcus agalactiae 2603V/R hypothetical protein NP_687267.1 241669 D 208435 CDS NP_687268.1 22536417 1013007 242202..242882 1 NC_004116.1 hypothetical protein 242882 1013007 SAG0233 Streptococcus agalactiae 2603V/R hypothetical protein NP_687268.1 242202 D 208435 CDS NP_687269.1 22536418 1013008 242867..243253 1 NC_004116.1 hypothetical protein 243253 1013008 SAG0234 Streptococcus agalactiae 2603V/R hypothetical protein NP_687269.1 242867 D 208435 CDS NP_687270.1 22536419 1013009 243287..243568 1 NC_004116.1 hypothetical protein 243568 1013009 SAG0235 Streptococcus agalactiae 2603V/R hypothetical protein NP_687270.1 243287 D 208435 CDS NP_687271.1 22536420 1013010 243659..243757 1 NC_004116.1 hypothetical protein 243757 1013010 SAG0236 Streptococcus agalactiae 2603V/R hypothetical protein NP_687271.1 243659 D 208435 CDS NP_687272.1 22536421 1013011 244185..244289 1 NC_004116.1 hypothetical protein 244289 1013011 SAG0237 Streptococcus agalactiae 2603V/R hypothetical protein NP_687272.1 244185 D 208435 CDS NP_687273.1 22536422 1013012 244286..244411 1 NC_004116.1 hypothetical protein 244411 1013012 SAG0238 Streptococcus agalactiae 2603V/R hypothetical protein NP_687273.1 244286 D 208435 CDS NP_687274.1 22536423 1013013 244411..245271 1 NC_004116.1 MutR family transcriptional regulator 245271 1013013 SAG0239 Streptococcus agalactiae 2603V/R MutR family transcriptional regulator NP_687274.1 244411 D 208435 CDS NP_687275.1 22536424 1013014 245344..246525 1 NC_004116.1 transporter 246525 1013014 SAG0240 Streptococcus agalactiae 2603V/R transporter NP_687275.1 245344 D 208435 CDS NP_687276.1 22536425 1013015 complement(246587..247228) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00528; amino acid ABC transporter permease 247228 1013015 SAG0241 Streptococcus agalactiae 2603V/R amino acid ABC transporter permease NP_687276.1 246587 R 208435 CDS NP_687277.1 22536426 1013016 complement(247238..248164) 1 NC_004116.1 similar to GB:AL009126; identified by sequence similarity; amino acid ABC transporter amino acid-binding protein 248164 1013016 SAG0242 Streptococcus agalactiae 2603V/R amino acid ABC transporter amino acid-binding protein NP_687277.1 247238 R 208435 CDS NP_687278.1 22536427 1013017 complement(248167..248802) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00528; amino acid ABC transporter permease 248802 1013017 SAG0243 Streptococcus agalactiae 2603V/R amino acid ABC transporter permease NP_687278.1 248167 R 208435 CDS NP_687279.1 22536428 1013018 complement(248802..249947) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00005; amino acid ABC transporter ATP-binding protein 249947 1013018 SAG0244 Streptococcus agalactiae 2603V/R amino acid ABC transporter ATP-binding protein NP_687279.1 248802 R 208435 CDS NP_687280.1 22536429 1013034 256634..257092 1 NC_004116.1 identified by Glimmer2; The product of this gene was detected by Western blot analysis. For details on the method see Tettelin et al. 2002.; hypothetical protein 257092 1013034 SAG0245 Streptococcus agalactiae 2603V/R hypothetical protein NP_687280.1 256634 D 208435 CDS NP_687281.1 22536430 1013035 257156..257962 1 NC_004116.1 hypothetical protein 257962 1013035 SAG0246 Streptococcus agalactiae 2603V/R hypothetical protein NP_687281.1 257156 D 208435 CDS NP_687282.1 22536431 1013036 258440..258790 1 NC_004116.1 hypothetical protein 258790 1013036 SAG0247 Streptococcus agalactiae 2603V/R hypothetical protein NP_687282.1 258440 D 208435 CDS NP_687283.1 22536432 1013037 258809..259081 1 NC_004116.1 hypothetical protein 259081 1013037 SAG0248 Streptococcus agalactiae 2603V/R hypothetical protein NP_687283.1 258809 D 208435 CDS NP_687284.1 22536433 1013038 259091..259441 1 NC_004116.1 hypothetical protein 259441 1013038 SAG0249 Streptococcus agalactiae 2603V/R hypothetical protein NP_687284.1 259091 D 208435 CDS NP_687285.1 22536434 1013039 260302..260883 1 NC_004116.1 hypothetical protein 260883 1013039 SAG0250 Streptococcus agalactiae 2603V/R hypothetical protein NP_687285.1 260302 D 208435 CDS NP_687286.1 22536435 1013040 260886..261104 1 NC_004116.1 identified by match to PFAM protein family HMM PF01381; Cro/CI family transcriptional regulator 261104 1013040 SAG0251 Streptococcus agalactiae 2603V/R Cro/CI family transcriptional regulator NP_687286.1 260886 D 208435 CDS NP_687287.1 22536436 1013041 261677..262237 1 NC_004116.1 identified by match to PFAM protein family HMM PF00583; acetyltransferase 262237 1013041 SAG0252 Streptococcus agalactiae 2603V/R acetyltransferase NP_687287.1 261677 D 208435 CDS NP_687288.1 22536437 1013042 262337..262915 1 NC_004116.1 identified by match to PFAM protein family HMM PF00583; acetyltransferase 262915 1013042 SAG0253 Streptococcus agalactiae 2603V/R acetyltransferase NP_687288.1 262337 D 208435 CDS NP_687289.1 22536438 1013043 262958..263638 1 NC_004116.1 identified by match to PFAM protein family HMM PF00583; acetyltransferase 263638 1013043 SAG0254 Streptococcus agalactiae 2603V/R acetyltransferase NP_687289.1 262958 D 208435 CDS NP_687290.1 22536439 1013044 complement(263898..264845) 1 NC_004116.1 hypothetical protein 264845 1013044 SAG0255 Streptococcus agalactiae 2603V/R hypothetical protein NP_687290.1 263898 R 208435 CDS NP_687291.1 22536440 1013045 complement(264842..265333) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00776; ECF subfamily RNA polymerase sigma factor 265333 1013045 SAG0256 Streptococcus agalactiae 2603V/R ECF subfamily RNA polymerase sigma factor NP_687291.1 264842 R 208435 CDS NP_687292.1 22536441 1013046 265617..265778 1 NC_004116.1 lipoprotein 265778 1013046 SAG0257 Streptococcus agalactiae 2603V/R lipoprotein NP_687292.1 265617 D 208435 CDS NP_687293.1 22536442 1013047 complement(265913..266521) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00440; TetR family transcriptional regulator 266521 1013047 SAG0258 Streptococcus agalactiae 2603V/R TetR family transcriptional regulator NP_687293.1 265913 R 208435 CDS NP_687294.1 22536443 1013048 complement(266545..267642) 1 NC_004116.1 ABC transporter 267642 1013048 SAG0259 Streptococcus agalactiae 2603V/R ABC transporter NP_687294.1 266545 R 208435 CDS NP_687295.1 22536444 1013049 complement(267645..268361) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00005; ABC transporter ATP-binding protein 268361 1013049 SAG0260 Streptococcus agalactiae 2603V/R ABC transporter ATP-binding protein NP_687295.1 267645 R 208435 CDS NP_687296.1 22536445 1013050 complement(268657..269046) 1 NC_004116.1 identified by match to PFAM protein family HMM PF01609; IS1381 transposase protein B 269046 1013050 SAG0261 Streptococcus agalactiae 2603V/R IS1381 transposase protein B NP_687296.1 268657 R 208435 CDS NP_687297.1 22536446 1013051 complement(269079..269462) 1 NC_004116.1 similar to OMNI:SP0537; identified by sequence similarity; IS1381 transposase protein A 269462 1013051 SAG0262 Streptococcus agalactiae 2603V/R IS1381 transposase protein A NP_687297.1 269079 R 208435 CDS NP_687298.1 22536447 1013052 complement(269498..270013) 1 NC_004116.1 hypothetical protein 270013 1013052 SAG0263 Streptococcus agalactiae 2603V/R hypothetical protein NP_687298.1 269498 R 208435 CDS NP_687299.1 22536448 1013053 complement(270190..270501) 1 NC_004116.1 hypothetical protein 270501 1013053 SAG0264 Streptococcus agalactiae 2603V/R hypothetical protein NP_687299.1 270190 R 208435 CDS NP_687300.1 22536449 1013054 270693..271400 1 NC_004116.1 identified by Glimmer2; The product of this gene was detected by Western blot analysis. For details on the method see Tettelin et al. 2002.; hypothetical protein 271400 1013054 SAG0265 Streptococcus agalactiae 2603V/R hypothetical protein NP_687300.1 270693 D 208435 CDS NP_687301.1 22536450 1013055 271678..272826 1 NC_004116.1 identified by match to PFAM protein family HMM PF02612; N-acetylglucosamine-6-phosphate deacetylase 272826 nagA 1013055 nagA Streptococcus agalactiae 2603V/R N-acetylglucosamine-6-phosphate deacetylase NP_687301.1 271678 D 208435 CDS NP_687302.1 22536451 1013056 272945..273487 1 NC_004116.1 hypothetical protein 273487 1013056 SAG0267 Streptococcus agalactiae 2603V/R hypothetical protein NP_687302.1 272945 D 208435 CDS NP_687303.1 22536452 1013057 273800..274714 1 NC_004116.1 glycine--tRNA ligase alpha chain; GlyRS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; glycyl-tRNA synthetase subunit alpha 274714 glyQ 1013057 glyQ Streptococcus agalactiae 2603V/R glycyl-tRNA synthetase subunit alpha NP_687303.1 273800 D 208435 CDS NP_687304.1 22536453 1013058 274714..275355 1 NC_004116.1 ACP phosphodieterase 275355 1013058 SAG0269 Streptococcus agalactiae 2603V/R ACP phosphodieterase NP_687304.1 274714 D 208435 CDS NP_687305.1 22536454 1013059 275359..277398 1 NC_004116.1 glycine--tRNA ligase beta chain; glyS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; glycyl-tRNA synthetase subunit beta 277398 glyS 1013059 glyS Streptococcus agalactiae 2603V/R glycyl-tRNA synthetase subunit beta NP_687305.1 275359 D 208435 CDS NP_687306.1 22536455 1013060 277410..277667 1 NC_004116.1 hypothetical protein 277667 1013060 SAG0271 Streptococcus agalactiae 2603V/R hypothetical protein NP_687306.1 277410 D 208435 CDS NP_687307.1 22536456 1013061 277756..278019 1 NC_004116.1 similar to OMNI:NTL01SPL1075; identified by sequence similarity; hypothetical protein 278019 1013061 SAG0272 Streptococcus agalactiae 2603V/R hypothetical protein NP_687307.1 277756 D 208435 CDS NP_687308.1 22536457 1013062 278134..279642 1 NC_004116.1 Converts glycerol and ADP to glycerol-3-phosphate and ADP; glycerol kinase 279642 glpK 1013062 glpK Streptococcus agalactiae 2603V/R glycerol kinase NP_687308.1 278134 D 208435 CDS NP_687309.1 22536458 1013063 279655..281484 1 NC_004116.1 identified by match to PFAM protein family HMM PF01224; alpha-glycerophosphate oxidase 281484 1013063 SAG0274 Streptococcus agalactiae 2603V/R alpha-glycerophosphate oxidase NP_687309.1 279655 D 208435 CDS NP_687310.1 22536459 1013064 281496..282194 1 NC_004116.1 identified by match to PFAM protein family HMM PF00230; glycerol uptake facilitator protein 282194 glpF-1 1013064 glpF-1 Streptococcus agalactiae 2603V/R glycerol uptake facilitator protein NP_687310.1 281496 D 208435 CDS NP_687311.1 22536460 1013065 282282..283619 1 NC_004116.1 identified by match to PFAM protein family HMM PF00070; NADH oxidase 283619 1013065 SAG0276 Streptococcus agalactiae 2603V/R NADH oxidase NP_687311.1 282282 D 208435 CDS NP_687312.1 22536461 1013066 283610..285040 1 NC_004116.1 hypothetical protein 285040 1013066 SAG0277 Streptococcus agalactiae 2603V/R hypothetical protein NP_687312.1 283610 D 208435 CDS NP_687313.1 22536462 1013067 285165..287150 1 NC_004116.1 catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase; transketolase 287150 tkt 1013067 tkt Streptococcus agalactiae 2603V/R transketolase NP_687313.1 285165 D 208435 CDS NP_687314.1 22536463 1013068 287363..287668 1 NC_004116.1 hypothetical protein 287668 1013068 SAG0279 Streptococcus agalactiae 2603V/R hypothetical protein NP_687314.1 287363 D 208435 CDS NP_687315.1 22536464 1013069 287688..288422 1 NC_004116.1 identified by match to PFAM protein family HMM PF00005; ABC transporter ATP-binding protein 288422 1013069 SAG0280 Streptococcus agalactiae 2603V/R ABC transporter ATP-binding protein NP_687315.1 287688 D 208435 CDS NP_687316.1 22536465 1013070 288426..290030 1 NC_004116.1 similar to OMNI:NTL01SPL1317; identified by sequence similarity; hypothetical protein 290030 1013070 SAG0281 Streptococcus agalactiae 2603V/R hypothetical protein NP_687316.1 288426 D 208435 CDS NP_687317.1 22536466 1013071 complement(290238..291623) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00367; PTS system transporter subunit IIBC 291623 1013071 SAG0282 Streptococcus agalactiae 2603V/R PTS system transporter subunit IIBC NP_687317.1 290238 R 208435 CDS NP_687318.1 22536467 1013072 291764..292567 1 NC_004116.1 catalyzes the formation of glutamate 5-phosphate from glutamate in proline biosynthesis; gamma-glutamyl kinase 292567 proB 1013072 proB Streptococcus agalactiae 2603V/R gamma-glutamyl kinase NP_687318.1 291764 D 208435 CDS NP_687319.1 22536468 1013073 292577..293830 1 NC_004116.1 Catalyzes the phosphorylation of L-glutamate during the proline biosynthesis pathway; gamma-glutamyl phosphate reductase 293830 proA 1013073 proA Streptococcus agalactiae 2603V/R gamma-glutamyl phosphate reductase NP_687319.1 292577 D 208435 CDS NP_687320.2 161485617 1013074 293913..294860 1 NC_004116.1 S-adenosyl-methyltransferase MraW 294860 mraW 1013074 mraW Streptococcus agalactiae 2603V/R S-adenosyl-methyltransferase MraW NP_687320.2 293913 D 208435 CDS NP_687321.1 22536470 1013075 294875..295201 1 NC_004116.1 similar to OMNI:SP0335; identified by sequence similarity; cell division protein FtsL 295201 1013075 SAG0286 Streptococcus agalactiae 2603V/R cell division protein FtsL NP_687321.1 294875 D 208435 CDS NP_687322.1 22536471 1013076 295205..297463 1 NC_004116.1 identified by match to PFAM protein family HMM PF00905; penicillin-binding protein 2X 297463 pbpX 1013076 pbpX Streptococcus agalactiae 2603V/R penicillin-binding protein 2X NP_687322.1 295205 D 208435 CDS NP_687323.1 22536472 1013077 297465..298475 1 NC_004116.1 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; phospho-N-acetylmuramoyl-pentapeptide- transferase 298475 mraY 1013077 mraY Streptococcus agalactiae 2603V/R phospho-N-acetylmuramoyl-pentapeptide- transferase NP_687323.1 297465 D 208435 CDS NP_687324.1 22536473 1013078 298573..299916 1 NC_004116.1 identified by match to PFAM protein family HMM PF00270; DEAD/DEAH box helicase 299916 1013078 SAG0289 Streptococcus agalactiae 2603V/R DEAD/DEAH box helicase NP_687324.1 298573 D 208435 CDS NP_687325.1 22536474 1013079 300054..300866 1 NC_004116.1 identified by match to PFAM protein family HMM PF00497; ABC transporter substrate-binding protein 300866 1013079 SAG0290 Streptococcus agalactiae 2603V/R ABC transporter substrate-binding protein NP_687325.1 300054 D 208435 CDS NP_687326.1 22536475 1013080 300961..301764 1 NC_004116.1 identified by match to PFAM protein family HMM PF00528; amino acid ABC transporter permease 301764 1013080 SAG0291 Streptococcus agalactiae 2603V/R amino acid ABC transporter permease NP_687326.1 300961 D 208435 CDS NP_687327.1 22536476 1013081 301764..302507 1 NC_004116.1 identified by match to PFAM protein family HMM PF00005; amino acid ABC transporter ATP-binding protein 302507 1013081 SAG0292 Streptococcus agalactiae 2603V/R amino acid ABC transporter ATP-binding protein NP_687327.1 301764 D 208435 CDS NP_687328.1 22536477 1013082 302629..302853 1 NC_004116.1 hypothetical protein 302853 1013082 SAG0293 Streptococcus agalactiae 2603V/R hypothetical protein NP_687328.1 302629 D 208435 CDS NP_687329.1 22536478 1013083 302922..303836 1 NC_004116.1 identified by match to PFAM protein family HMM PF00070; thioredoxin reductase 303836 trxB 1013083 trxB Streptococcus agalactiae 2603V/R thioredoxin reductase NP_687329.1 302922 D 208435 CDS NP_687330.1 22536479 1013084 303994..305454 1 NC_004116.1 catalyzes the formation of 5-phospho-alpha-D-ribose 1-diphosphate and nicotinate from nicotinate D-ribonucleotide and diphosphate; nicotinate phosphoribosyltransferase 305454 1013084 SAG0295 Streptococcus agalactiae 2603V/R nicotinate phosphoribosyltransferase NP_687330.1 303994 D 208435 CDS NP_687331.1 22536480 1013085 305451..306272 1 NC_004116.1 catalyzes the formation of nicotinamide adenine dinucleotide (NAD) from nicotinic acid adenine dinucleotide (NAAD) using either ammonia or glutamine as the amide donor and ATP; ammonia-utilizing enzymes include the ones from Bacillus and Escherichia coli while glutamine-utilizing enzymes include the Mycobacterial one; forms homodimers; NAD synthetase 306272 nadE 1013085 nadE Streptococcus agalactiae 2603V/R NAD synthetase NP_687331.1 305451 D 208435 CDS NP_687332.1 22536481 1013086 306385..307719 1 NC_004116.1 identified by match to PFAM protein family HMM PF03051; aminopeptidase 307719 pepC 1013086 pepC Streptococcus agalactiae 2603V/R aminopeptidase NP_687332.1 306385 D 208435 CDS NP_687333.1 22536482 1013087 complement(307765..310017) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00905; penicillin-binding protein 1A 310017 pbp1A 1013087 pbp1A Streptococcus agalactiae 2603V/R penicillin-binding protein 1A NP_687333.1 307765 R 208435 CDS NP_687334.1 22536483 1013088 complement(310004..310603) 1 NC_004116.1 functions in homologous recombination, DNA repair, and chromosome segregation; binds preferentially to three- and four-stranded DNA intermediates; introduces specific nick sites in four-stranded DNA substrates; functions similarly to Escherichia coli RuvC; Holliday junction-specific endonuclease 310603 recU 1013088 recU Streptococcus agalactiae 2603V/R Holliday junction-specific endonuclease NP_687334.1 310004 R 208435 CDS NP_687335.1 22536484 1013089 310678..311196 1 NC_004116.1 hypothetical protein 311196 1013089 SAG0300 Streptococcus agalactiae 2603V/R hypothetical protein NP_687335.1 310678 D 208435 CDS NP_687336.1 22536485 1013090 311177..311299 1 NC_004116.1 hypothetical protein 311299 1013090 SAG0301 Streptococcus agalactiae 2603V/R hypothetical protein NP_687336.1 311177 D 208435 CDS NP_687337.1 22536486 1013091 311317..311649 1 NC_004116.1 GpsB; guiding PBP1 shuttling; similar to DivIVA; cell division protein GpsB 311649 1013091 SAG0302 Streptococcus agalactiae 2603V/R cell division protein GpsB NP_687337.1 311317 D 208435 CDS NP_687338.1 22536487 1013092 312119..313273 1 NC_004116.1 hypothetical protein 313273 1013092 SAG0303 Streptococcus agalactiae 2603V/R hypothetical protein NP_687338.1 312119 D 208435 CDS NP_687339.1 22536488 1013093 313286..314749 1 NC_004116.1 hypothetical protein 314749 1013093 SAG0304 Streptococcus agalactiae 2603V/R hypothetical protein NP_687339.1 313286 D 208435 CDS NP_687340.1 22536489 1013094 complement(314974..315456) 1 NC_004116.1 catalyzes the hydrolysis of S-ribosylhomocysteine to homocysteine and autoinducer-2; S-ribosylhomocysteinase 315456 luxS 1013094 luxS Streptococcus agalactiae 2603V/R S-ribosylhomocysteinase NP_687340.1 314974 R 208435 CDS NP_687341.1 22536490 1013095 315645..317252 1 NC_004116.1 identified by match to PFAM protein family HMM PF00013; hypothetical protein 317252 1013095 SAG0306 Streptococcus agalactiae 2603V/R hypothetical protein NP_687341.1 315645 D 208435 CDS NP_687342.1 22536491 1013096 317299..317400 1 NC_004116.1 hypothetical protein 317400 1013096 SAG0307 Streptococcus agalactiae 2603V/R hypothetical protein NP_687342.1 317299 D 208435 CDS NP_687343.1 22536492 1013097 317381..318277 1 NC_004116.1 identified by match to PFAM protein family HMM PF00005; ABC transporter ATP-binding protein 318277 1013097 SAG0308 Streptococcus agalactiae 2603V/R ABC transporter ATP-binding protein NP_687343.1 317381 D 208435 CDS NP_687344.1 22536493 1013098 318264..319004 1 NC_004116.1 hypothetical protein 319004 1013098 SAG0309 Streptococcus agalactiae 2603V/R hypothetical protein NP_687344.1 318264 D 208435 CDS NP_687345.1 22536494 1013099 319001..320086 1 NC_004116.1 hypothetical protein 320086 1013099 SAG0310 Streptococcus agalactiae 2603V/R hypothetical protein NP_687345.1 319001 D 208435 CDS NP_687346.1 22536495 1013101 320728..321432 1 NC_004116.1 hypothetical protein 321432 1013101 SAG0312 Streptococcus agalactiae 2603V/R hypothetical protein NP_687346.1 320728 D 208435 CDS NP_687347.1 22536496 1013102 321599..322228 1 NC_004116.1 Essential for recycling GMP and indirectly, cGMP; guanylate kinase 322228 gmk 1013102 gmk Streptococcus agalactiae 2603V/R guanylate kinase NP_687347.1 321599 D 208435 CDS NP_687348.1 22536497 1013103 322251..322565 1 NC_004116.1 Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits; DNA-directed RNA polymerase subunit omega 322565 1013103 SAG0314 Streptococcus agalactiae 2603V/R DNA-directed RNA polymerase subunit omega NP_687348.1 322251 D 208435 CDS NP_687349.1 22536498 1013104 322639..325029 1 NC_004116.1 binding of PriA to forked DNA starts the assembly of the primosome, also possesses 3'-5' helicase activity; primosome assembly protein PriA 325029 priA 1013104 priA Streptococcus agalactiae 2603V/R primosome assembly protein PriA NP_687349.1 322639 D 208435 CDS NP_687350.1 22536499 1013105 325076..326011 1 NC_004116.1 modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet) which is important in translation initiation; inactivation of this gene in Escherichia coli severely impairs growth; methionyl-tRNA formyltransferase 326011 fmt 1013105 fmt Streptococcus agalactiae 2603V/R methionyl-tRNA formyltransferase NP_687350.1 325076 D 208435 CDS NP_687351.1 22536500 1013106 326001..327323 1 NC_004116.1 identified by match to PFAM protein family HMM PF01029; sun protein 327323 sun 1013106 sun Streptococcus agalactiae 2603V/R sun protein NP_687351.1 326001 D 208435 CDS NP_687352.1 22536501 1013107 327361..328098 1 NC_004116.1 identified by match to PFAM protein family HMM PF00481; serine/threonine phosphatase 328098 1013107 SAG0318 Streptococcus agalactiae 2603V/R serine/threonine phosphatase NP_687352.1 327361 D 208435 CDS NP_687353.1 22536502 1013108 328098..330053 1 NC_004116.1 identified by match to PFAM protein family HMM PF00069; serine/threonine protein kinase 330053 1013108 SAG0319 Streptococcus agalactiae 2603V/R serine/threonine protein kinase NP_687353.1 328098 D 208435 CDS NP_687354.1 22536503 1013109 330214..330909 1 NC_004116.1 hypothetical protein 330909 1013109 SAG0320 Streptococcus agalactiae 2603V/R hypothetical protein NP_687354.1 330214 D 208435 CDS NP_687355.1 22536504 1013110 330906..331925 1 NC_004116.1 identified by match to PFAM protein family HMM PF02518; sensor histidine kinase 331925 1013110 SAG0321 Streptococcus agalactiae 2603V/R sensor histidine kinase NP_687355.1 330906 D 208435 CDS NP_687356.1 22536505 1013111 331918..332559 1 NC_004116.1 identified by match to PFAM protein family HMM PF00072; DNA-binding response regulator 332559 1013111 SAG0322 Streptococcus agalactiae 2603V/R DNA-binding response regulator NP_687356.1 331918 D 208435 CDS NP_687357.1 22536506 1013112 332601..334001 1 NC_004116.1 identified by match to PFAM protein family HMM PF00160; peptidyl-prolyl cis-trans isomerase 334001 1013112 SAG0323 Streptococcus agalactiae 2603V/R peptidyl-prolyl cis-trans isomerase NP_687357.1 332601 D 208435 CDS NP_687358.1 22536507 1013113 333985..334359 1 NC_004116.1 identified by match to PFAM protein family HMM PF00575; hypothetical protein 334359 1013113 SAG0324 Streptococcus agalactiae 2603V/R hypothetical protein NP_687358.1 333985 D 208435 CDS NP_687359.1 22536508 1013114 complement(334406..335182) 1 NC_004116.1 identified by match to PFAM protein family HMM PF02143; pyruvate formate-lyase-activating enzyme 335182 pflA-1 1013114 pflA-1 Streptococcus agalactiae 2603V/R pyruvate formate-lyase-activating enzyme NP_687359.1 334406 R 208435 CDS NP_687360.1 22536509 1013115 335303..336058 1 NC_004116.1 identified by match to PFAM protein family HMM PF00455; DeoR family transcriptional regulator 336058 1013115 SAG0326 Streptococcus agalactiae 2603V/R DeoR family transcriptional regulator NP_687360.1 335303 D 208435 CDS NP_687361.1 22536510 1013116 336177..337160 1 NC_004116.1 transcriptional regulator 337160 1013116 SAG0327 Streptococcus agalactiae 2603V/R transcriptional regulator NP_687361.1 336177 D 208435 CDS NP_687362.1 22536511 1013117 337364..337687 1 NC_004116.1 identified by match to PFAM protein family HMM PF02255; PTS system cellobiose-specific transporter subunit IIA 337687 celC 1013117 celC Streptococcus agalactiae 2603V/R PTS system cellobiose-specific transporter subunit IIA NP_687362.1 337364 D 208435 CDS NP_687363.1 22536512 1013118 337704..338024 1 NC_004116.1 identified by match to PFAM protein family HMM PF02302; PTS system cellobiose-specific transporter subunit IIB 338024 1013118 SAG0329 Streptococcus agalactiae 2603V/R PTS system cellobiose-specific transporter subunit IIB NP_687363.1 337704 D 208435 CDS NP_687364.1 22536513 1013119 338026..339327 1 NC_004116.1 identified by match to PFAM protein family HMM PF02378; PTS system cellobiose-specific transporter subunit IIC 339327 celB 1013119 celB Streptococcus agalactiae 2603V/R PTS system cellobiose-specific transporter subunit IIC NP_687364.1 338026 D 208435 CDS NP_687365.1 22536514 1013120 339508..341964 1 NC_004116.1 identified by match to PFAM protein family HMM PF01228; formate acetyltransferase 341964 pflD-1 1013120 pflD-1 Streptococcus agalactiae 2603V/R formate acetyltransferase NP_687365.1 339508 D 208435 CDS NP_687366.1 22536515 1013121 341974..342642 1 NC_004116.1 similar to transaldolase from Escherichia coli; many organisms have multiple copies; fructose-6-phosphate aldolase 342642 1013121 SAG0332 Streptococcus agalactiae 2603V/R fructose-6-phosphate aldolase NP_687366.1 341974 D 208435 CDS NP_687367.1 22536516 1013122 342710..343798 1 NC_004116.1 forms dimers and octamers; involved in conversion of glycerol to dihydroxy-acetone; glycerol dehydrogenase 343798 gldA 1013122 gldA Streptococcus agalactiae 2603V/R glycerol dehydrogenase NP_687367.1 342710 D 208435 CDS NP_687368.1 22536517 1013123 complement(343950..344876) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00291; cysteine synthase A 344876 cysK 1013123 cysK Streptococcus agalactiae 2603V/R cysteine synthase A NP_687368.1 343950 R 208435 CDS NP_687369.1 22536518 1013124 complement(344967..345611) 1 NC_004116.1 hypothetical protein 345611 1013124 SAG0335 Streptococcus agalactiae 2603V/R hypothetical protein NP_687369.1 344967 R 208435 CDS NP_687370.1 22536519 1013125 345667..346956 1 NC_004116.1 identified by match to PFAM protein family HMM PF00270; helicase 346956 1013125 SAG0336 Streptococcus agalactiae 2603V/R helicase NP_687370.1 345667 D 208435 CDS NP_687371.1 22536520 1013126 346956..347621 1 NC_004116.1 competence protein F 347621 1013126 SAG0337 Streptococcus agalactiae 2603V/R competence protein F NP_687371.1 346956 D 208435 CDS NP_687372.1 22536521 1013127 347698..348252 1 NC_004116.1 identified by match to PFAM protein family HMM PF02482; ribosomal subunit interface protein 348252 yfiA 1013127 yfiA Streptococcus agalactiae 2603V/R ribosomal subunit interface protein NP_687372.1 347698 D 208435 CDS NP_687373.1 22536522 1013133 complement(353792..355144) 1 NC_004116.1 catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP; lysine and threonine sensitive; aspartate kinase 355144 1013133 SAG0339 Streptococcus agalactiae 2603V/R aspartate kinase NP_687373.1 353792 R 208435 CDS NP_687374.1 22536523 1013134 355238..355888 1 NC_004116.1 identified by match to PFAM protein family HMM PF00702; HAD superfamily hydrolase 355888 1013134 SAG0340 Streptococcus agalactiae 2603V/R HAD superfamily hydrolase NP_687374.1 355238 D 208435 CDS NP_687375.1 22536524 1013135 complement(355874..356023) 1 NC_004116.1 hypothetical protein 356023 1013135 SAG0341 Streptococcus agalactiae 2603V/R hypothetical protein NP_687375.1 355874 R 208435 CDS NP_687376.1 22536525 1013136 356025..356816 1 NC_004116.1 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; enoyl-CoA hydratase 356816 1013136 SAG0342 Streptococcus agalactiae 2603V/R enoyl-CoA hydratase NP_687376.1 356025 D 208435 CDS NP_687377.1 22536526 1013137 356912..357346 1 NC_004116.1 identified by match to PFAM protein family HMM PF01047; MarR family transcriptional regulator 357346 1013137 SAG0343 Streptococcus agalactiae 2603V/R MarR family transcriptional regulator NP_687377.1 356912 D 208435 CDS NP_687378.1 22536527 1013138 357346..358317 1 NC_004116.1 FabH; beta-ketoacyl-acyl carrier protein synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs; 3-oxoacyl-ACP synthase 358317 fabH 1013138 fabH Streptococcus agalactiae 2603V/R 3-oxoacyl-ACP synthase NP_687378.1 357346 D 208435 CDS NP_687379.1 22536528 1013139 358375..358599 1 NC_004116.1 carries the fatty acid chain in fatty acid biosynthesis; acyl carrier protein 358599 acpP 1013139 acpP Streptococcus agalactiae 2603V/R acyl carrier protein NP_687379.1 358375 D 208435 CDS NP_687380.1 22536529 1013140 358754..359713 1 NC_004116.1 identified by match to PFAM protein family HMM PF03060; enoyl-ACP reductase 359713 fabK 1013140 fabK Streptococcus agalactiae 2603V/R enoyl-ACP reductase NP_687380.1 358754 D 208435 CDS NP_687381.1 22536530 1013141 359733..360659 1 NC_004116.1 identified by match to PFAM protein family HMM PF00698; ACP S-malonyltransferase 360659 fabD 1013141 fabD Streptococcus agalactiae 2603V/R ACP S-malonyltransferase NP_687381.1 359733 D 208435 CDS NP_687382.1 22536531 1013142 360668..361402 1 NC_004116.1 catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis; 3-ketoacyl-ACP reductase 361402 fabG 1013142 fabG Streptococcus agalactiae 2603V/R 3-ketoacyl-ACP reductase NP_687382.1 360668 D 208435 CDS NP_687383.1 22536532 1013143 361418..362650 1 NC_004116.1 FabF; beta-ketoacyl-ACP synthase II, KASII; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP; 3-oxoacyl-ACP synthase 362650 fabF 1013143 fabF Streptococcus agalactiae 2603V/R 3-oxoacyl-ACP synthase NP_687383.1 361418 D 208435 CDS NP_687384.1 22536533 1013144 362652..363152 1 NC_004116.1 composes the biotin carboxyl carrier protein subunit of the acetyl-CoA carboxylase complex, the enzyme that catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, which in turn controls the rate of fatty acid metabolism; acetyl-CoA carboxylase biotin carboxyl carrier protein subunit 363152 accB 1013144 accB Streptococcus agalactiae 2603V/R acetyl-CoA carboxylase biotin carboxyl carrier protein subunit NP_687384.1 362652 D 208435 CDS NP_687385.1 22536534 1013145 363149..363571 1 NC_004116.1 in Pseudomonas aeruginosa this enzyme is a trimer of dimers; essential for membrane formation; performs third step of type II fatty acid biosynthesis; catalyzes dehydration of (3R)-hydroxyacyl-ACP to trans-2-acyl-ACP; (3R)-hydroxymyristoyl-ACP dehydratase 363571 fabZ 1013145 fabZ Streptococcus agalactiae 2603V/R (3R)-hydroxymyristoyl-ACP dehydratase NP_687385.1 363149 D 208435 CDS NP_687386.1 22536535 1013146 363609..364979 1 NC_004116.1 an AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism; acetyl-CoA carboxylase biotin carboxylase subunit 364979 accC 1013146 accC Streptococcus agalactiae 2603V/R acetyl-CoA carboxylase biotin carboxylase subunit NP_687386.1 363609 D 208435 CDS NP_687387.1 22536536 1013147 364988..365863 1 NC_004116.1 catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer of AccA2D2 subunits; acetyl-CoA carboxylase subunit beta 365863 accD 1013147 accD Streptococcus agalactiae 2603V/R acetyl-CoA carboxylase subunit beta NP_687387.1 364988 D 208435 CDS NP_687388.1 22536537 1013148 365856..366629 1 NC_004116.1 catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer composed of two alpha (AccA) and two beta (AccD) subunits; one of the two catalytic subunits that can form the acetyl CoA carboxylase enzyme together with a carrier protein; these proteins present a shorter N-terminus; acetyl-CoA carboxylase subunit alpha 366629 accA 1013148 accA Streptococcus agalactiae 2603V/R acetyl-CoA carboxylase subunit alpha NP_687388.1 365856 D 208435 CDS NP_687389.1 22536538 1013149 367099..367731 1 NC_004116.1 hypothetical protein 367731 1013149 SAG0355 Streptococcus agalactiae 2603V/R hypothetical protein NP_687389.1 367099 D 208435 CDS NP_687390.1 22536539 1013150 complement(367777..369054) 1 NC_004116.1 catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; seryl-tRNA synthetase 369054 serS 1013150 serS Streptococcus agalactiae 2603V/R seryl-tRNA synthetase NP_687390.1 367777 R 208435 CDS NP_687391.1 22536540 1013151 369420..370412 1 NC_004116.1 hypothetical protein 370412 1013151 SAG0357 Streptococcus agalactiae 2603V/R hypothetical protein NP_687391.1 369420 D 208435 CDS NP_687392.1 22536541 1013152 complement(370450..370812) 1 NC_004116.1 hypothetical protein 370812 1013152 SAG0358 Streptococcus agalactiae 2603V/R hypothetical protein NP_687392.1 370450 R 208435 CDS NP_687393.1 22536542 1013153 complement(370931..371842) 1 NC_004116.1 PTS system mannose-specific transporter subunit IID 371842 1013153 SAG0359 Streptococcus agalactiae 2603V/R PTS system mannose-specific transporter subunit IID NP_687393.1 370931 R 208435 CDS NP_687394.1 22536543 1013154 complement(371857..372669) 1 NC_004116.1 PTS system mannose-specific transporter subunit IIC 372669 manM 1013154 manM Streptococcus agalactiae 2603V/R PTS system mannose-specific transporter subunit IIC NP_687394.1 371857 R 208435 CDS NP_687395.1 22536544 1013155 complement(372702..373712) 1 NC_004116.1 PTS system mannose-specific transporter subunit IIAB 373712 manL 1013155 manL Streptococcus agalactiae 2603V/R PTS system mannose-specific transporter subunit IIAB NP_687395.1 372702 R 208435 CDS NP_687396.1 22536545 1013156 complement(374015..374827) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00702; HAD superfamily hydrolase 374827 1013156 SAG0362 Streptococcus agalactiae 2603V/R HAD superfamily hydrolase NP_687396.1 374015 R 208435 CDS NP_687397.1 22536546 1013157 374916..375500 1 NC_004116.1 hypothetical protein 375500 1013157 SAG0363 Streptococcus agalactiae 2603V/R hypothetical protein NP_687397.1 374916 D 208435 CDS NP_687398.1 22536547 1013158 375590..376201 1 NC_004116.1 similar to GB:AE000520; identified by sequence similarity; hypothetical protein 376201 1013158 SAG0364 Streptococcus agalactiae 2603V/R hypothetical protein NP_687398.1 375590 D 208435 CDS NP_687399.1 22536548 1013159 376304..377725 1 NC_004116.1 identified by match to PFAM protein family HMM PF00860; xanthine/uracil permease family protein 377725 1013159 SAG0365 Streptococcus agalactiae 2603V/R xanthine/uracil permease family protein NP_687399.1 376304 D 208435 CDS NP_687400.1 22536549 1013160 377808..378317 1 NC_004116.1 hypothetical protein 378317 1013160 SAG0366 Streptococcus agalactiae 2603V/R hypothetical protein NP_687400.1 377808 D 208435 CDS NP_687401.1 22536550 1013161 378271..378831 1 NC_004116.1 identified by match to PFAM protein family HMM PF00583; acetyltransferase 378831 1013161 SAG0367 Streptococcus agalactiae 2603V/R acetyltransferase NP_687401.1 378271 D 208435 CDS NP_687402.1 22536551 1013162 378840..380147 1 NC_004116.1 identified by match to TIGR protein family HMM TIGR00350; The product of this gene was detected by Western blot analysis. For details on the method see Tettelin et al. 2002.; hypothetical protein 380147 1013162 SAG0368 Streptococcus agalactiae 2603V/R hypothetical protein NP_687402.1 378840 D 208435 CDS NP_687403.1 22536552 1013163 complement(380211..380507) 1 NC_004116.1 hypothetical protein 380507 1013163 SAG0369 Streptococcus agalactiae 2603V/R hypothetical protein NP_687403.1 380211 R 208435 CDS NP_687404.1 22536553 1013164 complement(380504..380923) 1 NC_004116.1 identified by match to PFAM protein family HMM PF01230; HIT family protein 380923 hit 1013164 hit Streptococcus agalactiae 2603V/R HIT family protein NP_687404.1 380504 R 208435 CDS NP_687405.1 22536554 1013165 381259..381762 1 NC_004116.1 hypothetical protein 381762 1013165 SAG0371 Streptococcus agalactiae 2603V/R hypothetical protein NP_687405.1 381259 D 208435 CDS NP_687406.1 22536555 1013166 complement(381814..382071) 1 NC_004116.1 hypothetical protein 382071 1013166 SAG0372 Streptococcus agalactiae 2603V/R hypothetical protein NP_687406.1 381814 R 208435 CDS NP_687407.1 22536556 1013167 382071..382796 1 NC_004116.1 identified by match to PFAM protein family HMM PF00005; ABC transporter ATP-binding protein 382796 1013167 SAG0373 Streptococcus agalactiae 2603V/R ABC transporter ATP-binding protein NP_687407.1 382071 D 208435 CDS NP_687408.1 22536557 1013168 382798..383832 1 NC_004116.1 similar to OMNI:NTL01SPL1360; identified by sequence similarity; ABC transporter permease 383832 1013168 SAG0374 Streptococcus agalactiae 2603V/R ABC transporter permease NP_687408.1 382798 D 208435 CDS NP_687409.1 22536558 1013169 383890..384690 1 NC_004116.1 hypothetical protein 384690 1013169 SAG0375 Streptococcus agalactiae 2603V/R hypothetical protein NP_687409.1 383890 D 208435 CDS NP_687410.1 22536559 1013170 384680..385315 1 NC_004116.1 tRNA (guanine-N(7)-)-methyltransferase; catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA by transferring the methyl residue from S-adenosyl-L-methionine; tRNA (guanine-N(7)-)-methyltransferase 385315 trmB 1013170 trmB Streptococcus agalactiae 2603V/R tRNA (guanine-N(7)-)-methyltransferase NP_687410.1 384680 D 208435 CDS NP_687411.1 22536560 1013172 385898..386281 1 NC_004116.1 in Streptococcus pneumoniae this gene was found to be essential; structure determination of the Streptococcus protein shows that it is similar to a number of other proteins; hypothetical protein 386281 1013172 SAG0377 Streptococcus agalactiae 2603V/R hypothetical protein NP_687411.1 385898 D 208435 CDS NP_687412.2 161485616 1013173 386317..387468 1 NC_004116.1 modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination; transcription elongation factor NusA 387468 nusA 1013173 nusA Streptococcus agalactiae 2603V/R transcription elongation factor NusA NP_687412.2 386317 D 208435 CDS NP_687413.1 22536562 1013174 387490..387786 1 NC_004116.1 hypothetical protein 387786 1013174 SAG0379 Streptococcus agalactiae 2603V/R hypothetical protein NP_687413.1 387490 D 208435 CDS NP_687414.1 22536563 1013175 387779..388081 1 NC_004116.1 identified by match to PFAM protein family HMM PF01248; hypothetical protein 388081 1013175 SAG0380 Streptococcus agalactiae 2603V/R hypothetical protein NP_687414.1 387779 D 208435 CDS NP_687415.1 22536564 1013176 388101..390884 1 NC_004116.1 Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; translation initiation factor IF-2 390884 infB 1013176 infB Streptococcus agalactiae 2603V/R translation initiation factor IF-2 NP_687415.1 388101 D 208435 CDS NP_687416.1 22536565 1013177 390975..391343 1 NC_004116.1 associates with free 30S ribosomal subunits; essential for efficient processing of 16S rRNA; in Escherichia coli rbfA is induced by cold shock; ribosome-binding factor A 391343 rbfA 1013177 rbfA Streptococcus agalactiae 2603V/R ribosome-binding factor A NP_687416.1 390975 D 208435 CDS NP_687417.1 22536566 1013178 complement(391427..392431) 1 NC_004116.1 similar to OMNI:NTL01SPL1351; identified by sequence similarity; The product of this gene was detected by Western blot analysis. For details on the method see Tettelin et al. 2002.; hypothetical protein 392431 1013178 SAG0383 Streptococcus agalactiae 2603V/R hypothetical protein NP_687417.1 391427 R 208435 CDS NP_687418.1 22536567 1013179 392595..393011 1 NC_004116.1 transcriptional repressor CopY 393011 1013179 SAG0384 Streptococcus agalactiae 2603V/R transcriptional repressor CopY NP_687418.1 392595 D 208435 CDS NP_687419.1 22536568 1013180 393024..395258 1 NC_004116.1 identified by match to PFAM protein family HMM PF00122; copper-transporter ATPase CopA 395258 1013180 SAG0385 Streptococcus agalactiae 2603V/R copper-transporter ATPase CopA NP_687419.1 393024 D 208435 CDS NP_687420.1 22536569 1013181 395299..395505 1 NC_004116.1 identified by match to PFAM protein family HMM PF00403; copper-transporter protein CopZ 395505 1013181 SAG0386 Streptococcus agalactiae 2603V/R copper-transporter protein CopZ NP_687420.1 395299 D 208435 CDS NP_687421.1 22536570 1013182 395615..396229 1 NC_004116.1 identified by match to PFAM protein family HMM PF03458; hypothetical protein 396229 1013182 SAG0387 Streptococcus agalactiae 2603V/R hypothetical protein NP_687421.1 395615 D 208435 CDS NP_687422.1 22536571 1013183 396244..397056 1 NC_004116.1 identified by match to PFAM protein family HMM PF00702; HAD superfamily hydrolase 397056 1013183 SAG0388 Streptococcus agalactiae 2603V/R HAD superfamily hydrolase NP_687422.1 396244 D 208435 CDS NP_687423.1 22536572 1013184 397169..399811 1 NC_004116.1 has 3'-5' exonuclease, 5'-3' exonuclease and 5'-3'polymerase activities, primarily functions to fill gaps during DNA replication and repair; DNA polymerase I 399811 polA 1013184 polA Streptococcus agalactiae 2603V/R DNA polymerase I NP_687423.1 397169 D 208435 CDS NP_687424.1 22536573 1013185 399841..400281 1 NC_004116.1 identified by match to PFAM protein family HMM PF02629; CoA-binding domain-containing protein 400281 1013185 SAG0390 Streptococcus agalactiae 2603V/R CoA-binding domain-containing protein NP_687424.1 399841 D 208435 CDS NP_687425.1 22536574 1013186 400363..400842 1 NC_004116.1 identified by match to PFAM protein family HMM PF01475; FUR family transcriptional regulator 400842 1013186 SAG0391 Streptococcus agalactiae 2603V/R FUR family transcriptional regulator NP_687425.1 400363 D 208435 CDS NP_687426.1 22536575 1013187 400995..402560 1 NC_004116.1 identified by match to PFAM protein family HMM PF00746; The product of this gene was detected by Western blot analysis. For details on the method see Tettelin et al. 2002.; cell wall surface anchor family protein 402560 1013187 SAG0392 Streptococcus agalactiae 2603V/R cell wall surface anchor family protein NP_687426.1 400995 D 208435 CDS NP_687427.1 22536576 1013188 402673..403359 1 NC_004116.1 identified by match to PFAM protein family HMM PF00072; DNA-binding response regulator 403359 1013188 SAG0393 Streptococcus agalactiae 2603V/R DNA-binding response regulator NP_687427.1 402673 D 208435 CDS NP_687428.1 22536577 1013189 403361..404398 1 NC_004116.1 identified by match to PFAM protein family HMM PF00512; sensor histidine kinase 404398 1013189 SAG0394 Streptococcus agalactiae 2603V/R sensor histidine kinase NP_687428.1 403361 D 208435 CDS NP_687429.1 22536578 1013190 complement(404412..405152) 1 NC_004116.1 similar to OMNI:NTL01SPL0158; identified by sequence similarity; hypothetical protein 405152 1013190 SAG0395 Streptococcus agalactiae 2603V/R hypothetical protein NP_687429.1 404412 R 208435 CDS NP_687430.1 22536579 1013191 405339..406481 1 NC_004116.1 Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr); queuine tRNA-ribosyltransferase 406481 tgt 1013191 tgt Streptococcus agalactiae 2603V/R queuine tRNA-ribosyltransferase NP_687430.1 405339 D 208435 CDS NP_687431.1 22536580 1013192 406591..406899 1 NC_004116.1 hypothetical protein 406899 1013192 SAG0397 Streptococcus agalactiae 2603V/R hypothetical protein NP_687431.1 406591 D 208435 CDS NP_687432.1 22536581 1013193 406906..407445 1 NC_004116.1 identified by match to PFAM protein family HMM PF02632; BioY family protein 407445 1013193 SAG0398 Streptococcus agalactiae 2603V/R BioY family protein NP_687432.1 406906 D 208435 CDS NP_687433.1 22536582 1013194 407584..408360 1 NC_004116.1 AtsA/ElaC family protein 408360 1013194 SAG0399 Streptococcus agalactiae 2603V/R AtsA/ElaC family protein NP_687433.1 407584 D 208435 CDS NP_687434.1 22536583 1013195 408360..408866 1 NC_004116.1 identified by match to PFAM protein family HMM PF00383; cytidine/deoxycytidylate deaminase family protein 408866 1013195 SAG0400 Streptococcus agalactiae 2603V/R cytidine/deoxycytidylate deaminase family protein NP_687434.1 408360 D 208435 CDS NP_687435.1 22536584 1013196 408968..409102 1 NC_004116.1 hypothetical protein 409102 1013196 SAG0401 Streptococcus agalactiae 2603V/R hypothetical protein NP_687435.1 408968 D 208435 CDS NP_687436.1 22536585 1013197 409138..410487 1 NC_004116.1 functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis; catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate; member of PGI family; glucose-6-phosphate isomerase 410487 pgi 1013197 pgi Streptococcus agalactiae 2603V/R glucose-6-phosphate isomerase NP_687436.1 409138 D 208435 CDS NP_687437.1 22536586 1013198 410809..411336 1 NC_004116.1 identified by match to PFAM protein family HMM PF01812; 5-formyltetrahydrofolate cyclo-ligase 411336 1013198 SAG0403 Streptococcus agalactiae 2603V/R 5-formyltetrahydrofolate cyclo-ligase NP_687437.1 410809 D 208435 CDS NP_687438.1 22536587 1013199 411327..412004 1 NC_004116.1 identified by match to PFAM protein family HMM PF01694; rhomboid family protein 412004 1013199 SAG0404 Streptococcus agalactiae 2603V/R rhomboid family protein NP_687438.1 411327 D 208435 CDS NP_687439.1 22536588 1013200 412136..413179 1 NC_004116.1 identified by match to PFAM protein family HMM PF02608; The product of this gene was detected by Western blot analysis. For details on the method see Tettelin et al. 2002.; hypothetical protein 413179 1013200 SAG0405 Streptococcus agalactiae 2603V/R hypothetical protein NP_687439.1 412136 D 208435 CDS NP_687440.1 22536589 1013201 complement(413270..414169) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00483; UTP-glucose-1-phosphate uridylyltransferase 414169 galU 1013201 galU Streptococcus agalactiae 2603V/R UTP-glucose-1-phosphate uridylyltransferase NP_687440.1 413270 R 208435 CDS NP_687441.1 22536590 1013202 complement(414206..415222) 1 NC_004116.1 catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate; NAD(P)H-dependent glycerol-3-phosphate dehydrogenase 415222 gpsA 1013202 gpsA Streptococcus agalactiae 2603V/R NAD(P)H-dependent glycerol-3-phosphate dehydrogenase NP_687441.1 414206 R 208435 CDS NP_687442.1 22536591 1013203 415392..415721 1 NC_004116.1 protein component of RNaseP which catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'terminus; this enzyme also cleaves other RNA substrates; ribonuclease P 415721 rnpA 1013203 rnpA Streptococcus agalactiae 2603V/R ribonuclease P NP_687442.1 415392 D 208435 CDS NP_687443.1 22536592 1013204 415734..416549 1 NC_004116.1 identified by match to PFAM protein family HMM PF02096; SpoIIIJ family protein 416549 1013204 SAG0409 Streptococcus agalactiae 2603V/R SpoIIIJ family protein NP_687443.1 415734 D 208435 CDS NP_687444.1 22536593 1013205 416557..417378 1 NC_004116.1 identified by match to PFAM protein family HMM PF01424; R3H domain-containing protein 417378 1013205 SAG0410 Streptococcus agalactiae 2603V/R R3H domain-containing protein NP_687444.1 416557 D 208435 CDS NP_687445.1 22536594 1013213 complement(423100..423633) 1 NC_004116.1 hypothetical protein 423633 1013213 SAG0411 Streptococcus agalactiae 2603V/R hypothetical protein NP_687445.1 423100 R 208435 CDS NP_687446.1 22536595 1013214 complement(423717..424493) 1 NC_004116.1 binds RecA and inhibits RecA-mediated DNA strand exchange and ATP hydrolysis and coprotease activities; RecX family transcriptional regulator 424493 recX 1013214 recX Streptococcus agalactiae 2603V/R RecX family transcriptional regulator NP_687446.1 423717 R 208435 CDS NP_687447.1 22536596 1013215 424592..425947 1 NC_004116.1 identified by match to PFAM protein family HMM PF01938; RNA methyltransferase 425947 1013215 SAG0413 Streptococcus agalactiae 2603V/R RNA methyltransferase NP_687447.1 424592 D 208435 CDS NP_687448.1 22536597 1013216 426216..426677 1 NC_004116.1 hypothetical protein 426677 1013216 SAG0414 Streptococcus agalactiae 2603V/R hypothetical protein NP_687448.1 426216 D 208435 CDS NP_687449.1 22536598 1013217 426820..427248 1 NC_004116.1 identified by match to PFAM protein family HMM PF00583; acetyltransferase 427248 1013217 SAG0415 Streptococcus agalactiae 2603V/R acetyltransferase NP_687449.1 426820 D 208435 CDS NP_687450.1 22536599 1013218 427436..431137 1 NC_004116.1 identified by match to PFAM protein family HMM PF00082; The product of this gene was detected by Western blot analysis. For details on the method see Tettelin et al. 2002.; protease 431137 1013218 SAG0416 Streptococcus agalactiae 2603V/R protease NP_687450.1 427436 D 208435 CDS NP_687451.1 22536600 1013219 431347..432255 1 NC_004116.1 identified by match to PFAM protein family HMM PF00535; glycosyl transferase family protein 432255 1013219 SAG0417 Streptococcus agalactiae 2603V/R glycosyl transferase family protein NP_687451.1 431347 D 208435 CDS NP_687452.1 22536601 1013220 432807..433817 1 NC_004116.1 B2 or R2 protein; type 1b enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdE; ribonucleotide-diphosphate reductase subunit beta 433817 nrdF 1013220 nrdF Streptococcus agalactiae 2603V/R ribonucleotide-diphosphate reductase subunit beta NP_687452.1 432807 D 208435 CDS NP_687453.1 22536602 1013221 433818..434231 1 NC_004116.1 in Salmonella NrdI has a stimulatory effect on the ribonucleotide reductase activity of NrdH with NrdEF; ribonucleotide reductase stimulatory protein 434231 nrdI 1013221 nrdI Streptococcus agalactiae 2603V/R ribonucleotide reductase stimulatory protein NP_687453.1 433818 D 208435 CDS NP_687454.1 22536603 1013222 434233..436398 1 NC_004116.1 Catalyzes the rate-limiting step in dNTP synthesis; ribonucleotide-diphosphate reductase subunit alpha 436398 nrdE-1 1013222 nrdE-1 Streptococcus agalactiae 2603V/R ribonucleotide-diphosphate reductase subunit alpha NP_687454.1 434233 D 208435 CDS NP_687455.1 22536604 1013223 436461..439628 1 NC_004116.1 similar to OMNI:NTL01SPL0643; identified by sequence similarity; There are documented cases with S in place of G in the LPXTG motif. The product of this gene was detected by Western blot analysis. For details on the method see Tettelin et al. 2002.; hypothetical protein 439628 1013223 SAG0421 Streptococcus agalactiae 2603V/R hypothetical protein NP_687455.1 436461 D 208435 CDS NP_687456.1 22536605 1013224 439641..440030 1 NC_004116.1 hypothetical protein 440030 1013224 SAG0422 Streptococcus agalactiae 2603V/R hypothetical protein NP_687456.1 439641 D 208435 CDS NP_687457.1 22536606 1013225 complement(440074..440472) 1 NC_004116.1 similar to OMNI:NTL01CA0427; identified by sequence similarity; hypothetical protein 440472 1013225 SAG0423 Streptococcus agalactiae 2603V/R hypothetical protein NP_687457.1 440074 R 208435 CDS NP_687458.1 22536607 1013226 complement(440744..441028) 1 NC_004116.1 hypothetical protein 441028 1013226 SAG0424 Streptococcus agalactiae 2603V/R hypothetical protein NP_687458.1 440744 R 208435 CDS NP_687459.1 22536608 1013227 complement(441115..441432) 1 NC_004116.1 identified by match to PFAM protein family HMM PF02627; carboxymuconolactone decarboxylase family protein 441432 1013227 SAG0425 Streptococcus agalactiae 2603V/R carboxymuconolactone decarboxylase family protein NP_687459.1 441115 R 208435 CDS NP_687460.1 22536609 1013228 complement(441456..441851) 1 NC_004116.1 hypothetical protein 441851 1013228 SAG0426 Streptococcus agalactiae 2603V/R hypothetical protein NP_687460.1 441456 R 208435 CDS NP_687461.1 22536610 1013229 complement(441861..442250) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00376; MerR family transcriptional regulator 442250 1013229 SAG0427 Streptococcus agalactiae 2603V/R MerR family transcriptional regulator NP_687461.1 441861 R 208435 CDS NP_687462.1 22536611 1013230 complement(442266..443303) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00107; zinc-containing alcohol dehydrogenase 443303 1013230 SAG0428 Streptococcus agalactiae 2603V/R zinc-containing alcohol dehydrogenase NP_687462.1 442266 R 208435 CDS NP_687463.1 22536612 1013231 complement(443413..444267) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00248; aldo/keto reductase 444267 1013231 SAG0429 Streptococcus agalactiae 2603V/R aldo/keto reductase NP_687463.1 443413 R 208435 CDS NP_687464.1 22536613 1013232 complement(444352..445215) 1 NC_004116.1 identified by match to PFAM protein family HMM PF01545; cation efflux system protein 445215 1013232 SAG0430 Streptococcus agalactiae 2603V/R cation efflux system protein NP_687464.1 444352 R 208435 CDS NP_687465.1 22536614 1013233 445347..445871 1 NC_004116.1 identified by match to PFAM protein family HMM PF00440; TetR family transcriptional regulator 445871 1013233 SAG0431 Streptococcus agalactiae 2603V/R TetR family transcriptional regulator NP_687465.1 445347 D 208435 CDS NP_687466.1 22536615 1013234 complement(446066..447259) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00165; AraC family transcriptional regulator 447259 1013234 SAG0432 Streptococcus agalactiae 2603V/R AraC family transcriptional regulator NP_687466.1 446066 R 208435 CDS NP_687467.1 22536616 1013235 447507..451676 1 NC_004116.1 identified by match to PFAM protein family HMM PF00746; surface protein Rib 451676 1013235 SAG0433 Streptococcus agalactiae 2603V/R surface protein Rib NP_687467.1 447507 D 208435 CDS NP_687468.1 22536617 1013237 452388..452681 1 NC_004116.1 similar to PID:984582 GB:U00096 SP:Q47150 PID:1786420; identified by sequence similarity; DNA-damage-inducible protein J 452681 1013237 SAG0435 Streptococcus agalactiae 2603V/R DNA-damage-inducible protein J NP_687468.1 452388 D 208435 CDS NP_687469.1 22536618 1013238 452678..452866 1 NC_004116.1 hypothetical protein 452866 1013238 SAG0436 Streptococcus agalactiae 2603V/R hypothetical protein NP_687469.1 452678 D 208435 CDS NP_687470.1 22536619 1013239 453019..453390 1 NC_004116.1 lipoprotein 453390 1013239 SAG0437 Streptococcus agalactiae 2603V/R lipoprotein NP_687470.1 453019 D 208435 CDS NP_687471.1 22536620 1013243 455763..456017 1 NC_004116.1 hypothetical protein 456017 1013243 SAG0440 Streptococcus agalactiae 2603V/R hypothetical protein NP_687471.1 455763 D 208435 CDS NP_687472.1 22536621 1013244 456126..456437 1 NC_004116.1 similar to GP:13622655; identified by sequence similarity; hypothetical protein 456437 1013244 SAG0441 Streptococcus agalactiae 2603V/R hypothetical protein NP_687472.1 456126 D 208435 CDS NP_687473.1 22536622 1013245 456705..457274 1 NC_004116.1 identified by match to PFAM protein family HMM PF00583; acetyltransferase 457274 1013245 SAG0442 Streptococcus agalactiae 2603V/R acetyltransferase NP_687473.1 456705 D 208435 CDS NP_687474.1 22536623 1013246 457372..457956 1 NC_004116.1 identified by match to PFAM protein family HMM PF00583; acetyltransferase 457956 1013246 SAG0443 Streptococcus agalactiae 2603V/R acetyltransferase NP_687474.1 457372 D 208435 CDS NP_687475.1 22536624 1013247 457953..458519 1 NC_004116.1 hypothetical protein 458519 1013247 SAG0444 Streptococcus agalactiae 2603V/R hypothetical protein NP_687475.1 457953 D 208435 CDS NP_687476.1 22536625 1013248 458519..461170 1 NC_004116.1 valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain; valyl-tRNA synthetase 461170 valS 1013248 valS Streptococcus agalactiae 2603V/R valyl-tRNA synthetase NP_687476.1 458519 D 208435 CDS NP_687477.1 22536626 1013249 461341..462300 1 NC_004116.1 identified by match to PFAM protein family HMM PF01408; Gfo/Idh/MocA family oxidoreductase 462300 1013249 SAG0446 Streptococcus agalactiae 2603V/R Gfo/Idh/MocA family oxidoreductase NP_687477.1 461341 D 208435 CDS NP_687478.1 22536627 1013250 462461..463324 1 NC_004116.1 identified by match to PFAM protein family HMM PF01544; magnesium transporter CorA family protein 463324 1013250 SAG0447 Streptococcus agalactiae 2603V/R magnesium transporter CorA family protein NP_687478.1 462461 D 208435 CDS NP_687479.1 22536628 1013251 complement(463371..464546) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00872; IS256 family transposase 464546 1013251 SAG0448 Streptococcus agalactiae 2603V/R IS256 family transposase NP_687479.1 463371 R 208435 CDS NP_687480.1 22536629 1013252 464852..465916 1 NC_004116.1 hypothetical protein 465916 1013252 SAG0449 Streptococcus agalactiae 2603V/R hypothetical protein NP_687480.1 464852 D 208435 CDS NP_687481.1 22536630 1013253 466030..467022 1 NC_004116.1 catalyzes the formation of asparagine from aspartate and ammonia; asparagine synthetase AsnA 467022 asnA 1013253 asnA Streptococcus agalactiae 2603V/R asparagine synthetase AsnA NP_687481.1 466030 D 208435 CDS NP_687482.1 22536631 1013254 complement(467067..467516) 1 NC_004116.1 hypothetical protein 467516 1013254 SAG0451 Streptococcus agalactiae 2603V/R hypothetical protein NP_687482.1 467067 R 208435 CDS NP_687483.1 22536632 1013255 467646..468185 1 NC_004116.1 identified by match to TIGR protein family HMM TIGR00095; type II DNA modification methyltransferase 468185 1013255 SAG0452 Streptococcus agalactiae 2603V/R type II DNA modification methyltransferase NP_687483.1 467646 D 208435 CDS NP_687484.1 22536633 1013256 468197..468487 1 NC_004116.1 hypothetical protein 468487 1013256 SAG0453 Streptococcus agalactiae 2603V/R hypothetical protein NP_687484.1 468197 D 208435 CDS NP_687485.1 22536634 1013257 468484..468969 1 NC_004116.1 Catalyzes the conversion of ATP and pantetheine 4'-phosphate to diphosphate and 3'-dephospho-coA; phosphopantetheine adenylyltransferase 468969 coaD 1013257 coaD Streptococcus agalactiae 2603V/R phosphopantetheine adenylyltransferase NP_687485.1 468484 D 208435 CDS NP_687486.1 22536635 1013258 468959..470032 1 NC_004116.1 hypothetical protein 470032 1013258 SAG0455 Streptococcus agalactiae 2603V/R hypothetical protein NP_687486.1 468959 D 208435 CDS NP_687487.1 22536636 1013260 471508..472086 1 NC_004116.1 hypothetical protein 472086 1013260 SAG0457 Streptococcus agalactiae 2603V/R hypothetical protein NP_687487.1 471508 D 208435 CDS NP_687488.1 22536637 1013261 472137..473243 1 NC_004116.1 23S rRNA m2A2503 methyltransferase; methylates the C2 position of the A2530 nucleotide in 23S rRNA; may be involved in antibiotic resistance; ribosomal RNA large subunit methyltransferase N 473243 1013261 SAG0458 Streptococcus agalactiae 2603V/R ribosomal RNA large subunit methyltransferase N NP_687488.1 472137 D 208435 CDS NP_687489.1 22536638 1013262 473243..473758 1 NC_004116.1 similar to OMNI:SP0769; identified by sequence similarity; VanZF domain-containing protein 473758 1013262 SAG0459 Streptococcus agalactiae 2603V/R VanZF domain-containing protein NP_687489.1 473243 D 208435 CDS NP_687490.1 22536639 1013263 473937..475682 1 NC_004116.1 identified by match to PFAM protein family HMM PF00005; ABC transporter ATP-binding protein/permease 475682 1013263 SAG0460 Streptococcus agalactiae 2603V/R ABC transporter ATP-binding protein/permease NP_687490.1 473937 D 208435 CDS NP_687491.1 22536640 1013264 475672..477411 1 NC_004116.1 identified by match to PFAM protein family HMM PF00005; ABC transporter ATP-binding protein/permease 477411 1013264 SAG0461 Streptococcus agalactiae 2603V/R ABC transporter ATP-binding protein/permease NP_687491.1 475672 D 208435 CDS NP_687492.1 22536641 1013265 477539..478105 1 NC_004116.1 TrpG; with TrpE catalyzes the formation of anthranilate and glutamate from chorismate and glutamine; TrpG provides the glutamine amidotransferase activity; anthranilate synthase component II 478105 trpG 1013265 trpG Streptococcus agalactiae 2603V/R anthranilate synthase component II NP_687492.1 477539 D 208435 CDS NP_687493.1 22536642 1013266 complement(478172..478711) 1 NC_004116.1 identified by match to PFAM protein family HMM PF02632; BioY family protein 478711 1013266 SAG0463 Streptococcus agalactiae 2603V/R BioY family protein NP_687493.1 478172 R 208435 CDS NP_687494.1 22536643 1013267 complement(478712..479704) 1 NC_004116.1 identified by match to PFAM protein family HMM PF01792; biotin synthetase 479704 bioB 1013267 bioB Streptococcus agalactiae 2603V/R biotin synthetase NP_687494.1 478712 R 208435 CDS NP_687495.1 22536644 1013268 479828..480322 1 NC_004116.1 hypothetical protein 480322 1013268 SAG0465 Streptococcus agalactiae 2603V/R hypothetical protein NP_687495.1 479828 D 208435 CDS NP_687496.1 22536645 1013269 480332..481447 1 NC_004116.1 identified by match to PFAM protein family HMM PF00108; thiolase 481447 1013269 SAG0466 Streptococcus agalactiae 2603V/R thiolase NP_687496.1 480332 D 208435 CDS NP_687497.1 22536646 1013270 481440..482669 1 NC_004116.1 AMP-binding protein 482669 1013270 SAG0467 Streptococcus agalactiae 2603V/R AMP-binding protein NP_687497.1 481440 D 208435 CDS NP_687498.1 22536647 1013271 482782..483414 1 NC_004116.1 identified by match to PFAM protein family HMM PF00730; endonuclease III 483414 nth 1013271 nth Streptococcus agalactiae 2603V/R endonuclease III NP_687498.1 482782 D 208435 CDS NP_687499.1 22536648 1013272 complement(483415..483810) 1 NC_004116.1 similar to OMNI:SP1808; identified by sequence similarity; type IV prepilin peptidase-like protein 483810 1013272 SAG0469 Streptococcus agalactiae 2603V/R type IV prepilin peptidase-like protein NP_687499.1 483415 R 208435 CDS NP_687500.1 22536649 1013273 483965..484174 1 NC_004116.1 hypothetical protein 484174 1013273 SAG0470 Streptococcus agalactiae 2603V/R hypothetical protein NP_687500.1 483965 D 208435 CDS NP_687501.1 22536650 1013274 484171..485139 1 NC_004116.1 identified by match to PFAM protein family HMM PF00480; glucokinase 485139 glk 1013274 glk Streptococcus agalactiae 2603V/R glucokinase NP_687501.1 484171 D 208435 CDS NP_687502.1 22536651 1013275 485151..485531 1 NC_004116.1 identified by match to PFAM protein family HMM PF00581; The product of this gene was detected by Western blot analysis. For details on the method see Tettelin et al. 2002.; rhodanese-like domain-containing protein 485531 1013275 SAG0472 Streptococcus agalactiae 2603V/R rhodanese-like domain-containing protein NP_687502.1 485151 D 208435 CDS NP_687503.1 22536652 1013276 485763..487604 1 NC_004116.1 identified by match to PFAM protein family HMM PF00009; elongation factor Tu family protein 487604 1013276 SAG0473 Streptococcus agalactiae 2603V/R elongation factor Tu family protein NP_687503.1 485763 D 208435 CDS NP_687504.1 22536653 1013277 487649..487894 1 NC_004116.1 hypothetical protein 487894 1013277 SAG0474 Streptococcus agalactiae 2603V/R hypothetical protein NP_687504.1 487649 D 208435 CDS NP_687505.1 22536654 1013278 488024..489379 1 NC_004116.1 UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase 489379 murD 1013278 murD Streptococcus agalactiae 2603V/R UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase NP_687505.1 488024 D 208435 CDS NP_687506.1 22536655 1013279 489382..490458 1 NC_004116.1 UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; involved in cell wall formation; inner membrane-associated; last step of peptidoglycan synthesis; undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase 490458 murG 1013279 murG Streptococcus agalactiae 2603V/R undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase NP_687506.1 489382 D 208435 CDS NP_687507.1 22536656 1013280 490462..491598 1 NC_004116.1 similar to OMNI:SP0690; identified by sequence similarity; cell division protein DivIB 491598 1013280 SAG0477 Streptococcus agalactiae 2603V/R cell division protein DivIB NP_687507.1 490462 D 208435 CDS NP_687508.1 22536657 1013281 491954..493243 1 NC_004116.1 identified by match to PFAM protein family HMM PF02491; cell division protein FtsA 493243 ftsA 1013281 ftsA Streptococcus agalactiae 2603V/R cell division protein FtsA NP_687508.1 491954 D 208435 CDS NP_687509.1 22536658 1013282 493265..494545 1 NC_004116.1 GTPase; similar structure to tubulin; forms ring-shaped polymers at the site of cell division; other proteins such as FtsA, ZipA, and ZapA, interact with and regulate FtsZ function; cell division protein FtsZ 494545 ftsZ 1013282 ftsZ Streptococcus agalactiae 2603V/R cell division protein FtsZ NP_687509.1 493265 D 208435 CDS NP_687510.1 22536659 1013283 494551..495225 1 NC_004116.1 identified by match to PFAM protein family HMM PF01168; hypothetical protein 495225 1013283 SAG0480 Streptococcus agalactiae 2603V/R hypothetical protein NP_687510.1 494551 D 208435 CDS NP_687511.1 22536660 1013284 495237..495842 1 NC_004116.1 similar to GP:4009494; identified by sequence similarity; hypothetical protein 495842 ylmF 1013284 ylmF Streptococcus agalactiae 2603V/R hypothetical protein NP_687511.1 495237 D 208435 CDS NP_687512.1 22536661 1013285 495845..496099 1 NC_004116.1 identified by match to PFAM protein family HMM PF02325; hypothetical protein 496099 1013285 SAG0482 Streptococcus agalactiae 2603V/R hypothetical protein NP_687512.1 495845 D 208435 CDS NP_687513.1 22536662 1013286 496101..496889 1 NC_004116.1 identified by match to PFAM protein family HMM PF01479; hypothetical protein 496889 ylmH 1013286 ylmH Streptococcus agalactiae 2603V/R hypothetical protein NP_687513.1 496101 D 208435 CDS NP_687514.1 22536663 1013287 496899..497669 1 NC_004116.1 similar to OMNI:SP1661; identified by sequence similarity; cell division protein DivIVA 497669 1013287 SAG0484 Streptococcus agalactiae 2603V/R cell division protein DivIVA NP_687514.1 496899 D 208435 CDS NP_687515.1 22536664 1013288 497954..500746 1 NC_004116.1 IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase family; some organisms carry two different copies of this enzyme; isoleucyl-tRNA synthetase 500746 ileS 1013288 ileS Streptococcus agalactiae 2603V/R isoleucyl-tRNA synthetase NP_687515.1 497954 D 208435 CDS NP_687516.1 22536665 1013289 complement(500863..501165) 1 NC_004116.1 hypothetical protein 501165 1013289 SAG0486 Streptococcus agalactiae 2603V/R hypothetical protein NP_687516.1 500863 R 208435 CDS NP_687517.1 22536666 1013290 complement(501229..501684) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00293; MutT/nudix family protein 501684 1013290 SAG0487 Streptococcus agalactiae 2603V/R MutT/nudix family protein NP_687517.1 501229 R 208435 CDS NP_687518.1 22536667 1013291 complement(501870..504131) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00004; ATP-dependent Clp protease, ATP-binding subunit 504131 1013291 SAG0488 Streptococcus agalactiae 2603V/R ATP-dependent Clp protease, ATP-binding subunit NP_687518.1 501870 R 208435 CDS NP_687519.1 22536668 1013292 504287..504391 1 NC_004116.1 hypothetical protein 504391 1013292 SAG0489 Streptococcus agalactiae 2603V/R hypothetical protein NP_687519.1 504287 D 208435 CDS NP_687520.1 22536669 1013293 504429..504659 1 NC_004116.1 hypothetical protein 504659 1013293 SAG0490 Streptococcus agalactiae 2603V/R hypothetical protein NP_687520.1 504429 D 208435 CDS NP_687521.1 22536670 1013294 504801..505493 1 NC_004116.1 identified by match to PFAM protein family HMM PF00528; amino acid ABC transporter permease 505493 1013294 SAG0491 Streptococcus agalactiae 2603V/R amino acid ABC transporter permease NP_687521.1 504801 D 208435 CDS NP_687522.1 22536671 1013295 505486..506220 1 NC_004116.1 identified by match to PFAM protein family HMM PF00005; amino acid ABC transporter ATP-binding protein 506220 1013295 SAG0492 Streptococcus agalactiae 2603V/R amino acid ABC transporter ATP-binding protein NP_687522.1 505486 D 208435 CDS NP_687523.1 22536672 1013296 506507..508201 1 NC_004116.1 identified by match to PFAM protein family HMM PF00408; phosphoglucomutase/phosphomannomutase family protein 508201 1013296 SAG0493 Streptococcus agalactiae 2603V/R phosphoglucomutase/phosphomannomutase family protein NP_687523.1 506507 D 208435 CDS NP_687524.1 22536673 1013297 508340..509194 1 NC_004116.1 catalyzes the formation of 5,10-methenyltetrahydrofolate from 5,10-methylenetetrahydrofolate and subsequent formation of 10-formyltetrahydrofolate from 5,10-methenyltetrahydrofolate; bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase 509194 folD 1013297 folD Streptococcus agalactiae 2603V/R bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase NP_687524.1 508340 D 208435 CDS NP_687525.1 22536674 1013298 509191..510027 1 NC_004116.1 identified by match to PFAM protein family HMM PF01256; The product of this gene was detected by Western blot analysis. For details on the method see Tettelin et al. 2002.; hypothetical protein 510027 1013298 SAG0495 Streptococcus agalactiae 2603V/R hypothetical protein NP_687525.1 509191 D 208435 CDS NP_687526.1 22536675 1013299 510153..511493 1 NC_004116.1 bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides; exodeoxyribonuclease VII large subunit 511493 xseA 1013299 xseA Streptococcus agalactiae 2603V/R exodeoxyribonuclease VII large subunit NP_687526.1 510153 D 208435 CDS NP_687527.1 22536676 1013300 511471..511686 1 NC_004116.1 catalyzes the bidirectional exonucleolytic cleavage of DNA; exodeoxyribonuclease VII small subunit 511686 xseB 1013300 xseB Streptococcus agalactiae 2603V/R exodeoxyribonuclease VII small subunit NP_687527.1 511471 D 208435 CDS NP_687528.1 22536677 1013301 511686..512558 1 NC_004116.1 identified by match to PFAM protein family HMM PF00348; geranyltranstransferase 512558 1013301 SAG0498 Streptococcus agalactiae 2603V/R geranyltranstransferase NP_687528.1 511686 D 208435 CDS NP_687529.1 22536678 1013302 512551..513378 1 NC_004116.1 identified by match to PFAM protein family HMM PF01479; hemolysin A 513378 1013302 SAG0499 Streptococcus agalactiae 2603V/R hemolysin A NP_687529.1 512551 D 208435 CDS NP_687530.1 22536679 1013303 513365..513838 1 NC_004116.1 identified by match to PFAM protein family HMM PF01316; arginine repressor ArgR 513838 1013303 SAG0500 Streptococcus agalactiae 2603V/R arginine repressor ArgR NP_687530.1 513365 D 208435 CDS NP_687531.1 22536680 1013304 513850..515508 1 NC_004116.1 identified by match to PFAM protein family HMM PF02463; DNA repair protein RecN 515508 recN 1013304 recN Streptococcus agalactiae 2603V/R DNA repair protein RecN NP_687531.1 513850 D 208435 CDS NP_687532.1 22536681 1013305 515621..516457 1 NC_004116.1 identified by match to PFAM protein family HMM PF02645; The product of this gene was detected by Western blot analysis. For details on the method see Tettelin et al. 2002.; DegV family protein 516457 1013305 SAG0502 Streptococcus agalactiae 2603V/R DegV family protein NP_687532.1 515621 D 208435 CDS NP_687533.1 22536682 1013306 516450..517289 1 NC_004116.1 identified by match to PFAM protein family HMM PF00657; The product of this gene was detected by Western blot analysis. For details on the method see Tettelin et al. 2002.; lipase/acylhydrolase 517289 1013306 SAG0503 Streptococcus agalactiae 2603V/R lipase/acylhydrolase NP_687533.1 516450 D 208435 CDS NP_687534.1 22536683 1013307 517264..517866 1 NC_004116.1 hypothetical protein 517866 1013307 SAG0504 Streptococcus agalactiae 2603V/R hypothetical protein NP_687534.1 517264 D 208435 CDS NP_687535.1 22536684 1013308 517969..518244 1 NC_004116.1 identified by match to PFAM protein family HMM PF00216; DNA-binding protein HU 518244 hup 1013308 hup Streptococcus agalactiae 2603V/R DNA-binding protein HU NP_687535.1 517969 D 208435 CDS NP_687536.1 22536685 1013309 518441..518638 1 NC_004116.1 hypothetical protein 518638 1013309 SAG0506 Streptococcus agalactiae 2603V/R hypothetical protein NP_687536.1 518441 D 208435 CDS NP_687537.1 22536686 1013310 complement(518682..519614) 1 NC_004116.1 catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway; subclass 1A is a dimer formed by two identical PyrD subunits each containing an FMN group; dihydroorotate dehydrogenase 1A 519614 pyrDA 1013310 pyrDA Streptococcus agalactiae 2603V/R dihydroorotate dehydrogenase 1A NP_687537.1 518682 R 208435 CDS NP_687538.1 22536687 1013311 complement(519801..521036) 1 NC_004116.1 identified by match to PFAM protein family HMM PF02388; beta-lactam resistance factor 521036 fibB 1013311 fibB Streptococcus agalactiae 2603V/R beta-lactam resistance factor NP_687538.1 519801 R 208435 CDS NP_687539.1 22536688 1013312 complement(521055..522266) 1 NC_004116.1 identified by match to PFAM protein family HMM PF02388; beta-lactam resistance factor 522266 fibA 1013312 fibA Streptococcus agalactiae 2603V/R beta-lactam resistance factor NP_687539.1 521055 R 208435 CDS NP_687540.1 22536689 1013313 complement(522279..523499) 1 NC_004116.1 identified by match to PFAM protein family HMM PF02388; MurM protein 523499 1013313 SAG0510 Streptococcus agalactiae 2603V/R MurM protein NP_687540.1 522279 R 208435 CDS NP_687541.1 22536690 1013314 complement(523499..524311) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00702; HAD superfamily hydrolase 524311 1013314 SAG0511 Streptococcus agalactiae 2603V/R HAD superfamily hydrolase NP_687541.1 523499 R 208435 CDS NP_687542.1 22536691 1013315 complement(524382..525698) 1 NC_004116.1 identified by match to PFAM protein family HMM PF01966; HD domain-containing protein 525698 1013315 SAG0512 Streptococcus agalactiae 2603V/R HD domain-containing protein NP_687542.1 524382 R 208435 CDS NP_687543.1 22536692 1013316 525774..526160 1 NC_004116.1 hypothetical protein 526160 1013316 SAG0513 Streptococcus agalactiae 2603V/R hypothetical protein NP_687543.1 525774 D 208435 CDS NP_687544.1 22536693 1013317 526504..529188 1 NC_004116.1 identified by match to PFAM protein family HMM PF00122; cation transporter E1-E2 family ATPase 529188 1013317 SAG0514 Streptococcus agalactiae 2603V/R cation transporter E1-E2 family ATPase NP_687544.1 526504 D 208435 CDS NP_687545.1 22536694 1013318 complement(529233..530093) 1 NC_004116.1 hypothetical protein 530093 1013318 SAG0515 Streptococcus agalactiae 2603V/R hypothetical protein NP_687545.1 529233 R 208435 CDS NP_687546.1 22536695 1013319 530245..532176 1 NC_004116.1 similar to PID:1064791 GB:AL009126; identified by sequence similarity; fructose-1,6-bisphosphatase 532176 1013319 SAG0516 Streptococcus agalactiae 2603V/R fructose-1,6-bisphosphatase NP_687546.1 530245 D 208435 CDS NP_687547.1 22536696 1013320 532266..533390 1 NC_004116.1 identified by match to PFAM protein family HMM PF00037; (Fe-S)-binding protein 533390 1013320 SAG0517 Streptococcus agalactiae 2603V/R (Fe-S)-binding protein NP_687547.1 532266 D 208435 CDS NP_687548.1 22536697 1013322 534576..535268 1 NC_004116.1 identified by match to PFAM protein family HMM PF00005; cell division ABC transporter ATP-binding protein FtsE 535268 ftsE 1013322 ftsE Streptococcus agalactiae 2603V/R cell division ABC transporter ATP-binding protein FtsE NP_687548.1 534576 D 208435 CDS NP_687549.1 22536698 1013323 535252..536181 1 NC_004116.1 identified by match to PFAM protein family HMM PF02687; cell division ABC transporter permease FtsX 536181 ftsX 1013323 ftsX Streptococcus agalactiae 2603V/R cell division ABC transporter permease FtsX NP_687549.1 535252 D 208435 CDS NP_687550.1 22536699 1013324 complement(536234..536944) 1 NC_004116.1 similar to OMNI:EF0274; identified by sequence similarity; hypothetical protein 536944 1013324 SAG0521 Streptococcus agalactiae 2603V/R hypothetical protein NP_687550.1 536234 R 208435 CDS NP_687551.1 22536700 1013325 complement(536941..537639) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00753; metallo-beta-lactamase superfamily protein 537639 1013325 SAG0522 Streptococcus agalactiae 2603V/R metallo-beta-lactamase superfamily protein NP_687551.1 536941 R 208435 CDS NP_687552.1 22536701 1013326 537807..538571 1 NC_004116.1 identified by match to PFAM protein family HMM PF00106; acetoin reductase 538571 1013326 SAG0523 Streptococcus agalactiae 2603V/R acetoin reductase NP_687552.1 537807 D 208435 CDS NP_687553.1 22536702 1013327 538679..541186 1 NC_004116.1 unwinds DNA; bifunctional ATP-dependent DNA helicase/DNA polymerase III subunit epsilon 541186 1013327 SAG0524 Streptococcus agalactiae 2603V/R bifunctional ATP-dependent DNA helicase/DNA polymerase III subunit epsilon NP_687553.1 538679 D 208435 CDS NP_687554.1 22536703 1013328 541272..542465 1 NC_004116.1 catalyzes the formation of oxalozcetate and L-glutamate from L-aspartate and 2-oxoglutarate; aspartate aminotransferase 542465 aspC 1013328 aspC Streptococcus agalactiae 2603V/R aspartate aminotransferase NP_687554.1 541272 D 208435 CDS NP_687555.1 22536704 1013329 542486..543832 1 NC_004116.1 catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; asparaginyl-tRNA synthetase 543832 asnC 1013329 asnC Streptococcus agalactiae 2603V/R asparaginyl-tRNA synthetase NP_687555.1 542486 D 208435 CDS NP_687556.1 22536705 1013330 complement(543872..544429) 1 NC_004116.1 hypothetical protein 544429 1013330 SAG0527 Streptococcus agalactiae 2603V/R hypothetical protein NP_687556.1 543872 R 208435 CDS NP_687557.1 22536706 1013331 complement(544426..545409) 1 NC_004116.1 identified by match to PFAM protein family HMM PF01156; inosine-uridine preferring nucleoside hydrolase 545409 1013331 SAG0528 Streptococcus agalactiae 2603V/R inosine-uridine preferring nucleoside hydrolase NP_687557.1 544426 R 208435 CDS NP_687558.1 22536707 1013332 complement(545442..545558) 1 NC_004116.1 hypothetical protein 545558 1013332 SAG0529 Streptococcus agalactiae 2603V/R hypothetical protein NP_687558.1 545442 R 208435 CDS NP_687559.1 22536708 1013333 complement(545655..546068) 1 NC_004116.1 identified by match to PFAM protein family HMM PF02566; OsmC/Ohr family protein 546068 1013333 SAG0530 Streptococcus agalactiae 2603V/R OsmC/Ohr family protein NP_687559.1 545655 R 208435 CDS NP_687560.1 22536709 1013334 546222..547112 1 NC_004116.1 hypothetical protein 547112 1013334 SAG0531 Streptococcus agalactiae 2603V/R hypothetical protein NP_687560.1 546222 D 208435 CDS NP_687561.1 22536710 1013335 547109..548083 1 NC_004116.1 hypothetical protein 548083 1013335 SAG0532 Streptococcus agalactiae 2603V/R hypothetical protein NP_687561.1 547109 D 208435 CDS NP_687562.1 22536711 1013336 548080..548991 1 NC_004116.1 hypothetical protein 548991 1013336 SAG0533 Streptococcus agalactiae 2603V/R hypothetical protein NP_687562.1 548080 D 208435 CDS NP_687563.1 22536712 1013337 549006..550403 1 NC_004116.1 similar to OMNI:NTL01LL1596; identified by sequence similarity; dipeptidase 550403 1013337 SAG0534 Streptococcus agalactiae 2603V/R dipeptidase NP_687563.1 549006 D 208435 CDS NP_687564.1 22536713 1013338 550545..552065 1 NC_004116.1 identified by match to PFAM protein family HMM PF01297; zinc ABC transporter substrate-binding protein 552065 1013338 SAG0535 Streptococcus agalactiae 2603V/R zinc ABC transporter substrate-binding protein NP_687564.1 550545 D 208435 CDS NP_687565.1 22536714 1013339 complement(552178..552438) 1 NC_004116.1 RpmE2; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster do not have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome; 50S ribosomal protein L31 552438 rpmE2 1013339 rpmE2 Streptococcus agalactiae 2603V/R 50S ribosomal protein L31 NP_687565.1 552178 R 208435 CDS NP_687566.1 22536715 1013340 complement(552547..553482) 1 NC_004116.1 identified by match to PFAM protein family HMM PF01368; DHH family protein 553482 1013340 SAG0537 Streptococcus agalactiae 2603V/R DHH family protein NP_687566.1 552547 R 208435 CDS NP_687567.1 22536716 1013341 553748..554770 1 NC_004116.1 catalyzes the formation of inosine from adenosine; adenosine deaminase 554770 1013341 SAG0538 Streptococcus agalactiae 2603V/R adenosine deaminase NP_687567.1 553748 D 208435 CDS NP_687568.1 22536717 1013342 554829..555272 1 NC_004116.1 An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group; flavodoxin 555272 1013342 SAG0539 Streptococcus agalactiae 2603V/R flavodoxin NP_687568.1 554829 D 208435 CDS NP_687569.1 22536718 1013343 555349..555624 1 NC_004116.1 identified by match to PFAM protein family HMM PF01817; hypothetical protein 555624 1013343 SAG0540 Streptococcus agalactiae 2603V/R hypothetical protein NP_687569.1 555349 D 208435 CDS NP_687570.1 22536719 1013344 555617..556813 1 NC_004116.1 identified by match to PFAM protein family HMM PF00654; voltage-gated chloride channel family protein 556813 1013344 SAG0541 Streptococcus agalactiae 2603V/R voltage-gated chloride channel family protein NP_687570.1 555617 D 208435 CDS NP_687571.1 22536720 1013345 557266..557649 1 NC_004116.1 similar to OMNI:SP0537; identified by sequence similarity; IS1381 transposase protein A 557649 1013345 SAG0542 Streptococcus agalactiae 2603V/R IS1381 transposase protein A NP_687571.1 557266 D 208435 CDS NP_687572.1 22536721 1013346 557682..558071 1 NC_004116.1 identified by match to PFAM protein family HMM PF01609; IS1381 transposase protein B 558071 1013346 SAG0543 Streptococcus agalactiae 2603V/R IS1381 transposase protein B NP_687572.1 557682 D 208435 CDS NP_687573.1 22536722 1013347 558254..558601 1 NC_004116.1 this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site; 50S ribosomal protein L19 558601 rplS 1013347 rplS Streptococcus agalactiae 2603V/R 50S ribosomal protein L19 NP_687573.1 558254 D 208435 CDS NP_687574.1 22536723 1013349 complement(558826..559905) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00589; prophage LambdaSa1, site-specific recombinase phage integrase family protein 559905 1013349 SAG0545 Streptococcus agalactiae 2603V/R prophage LambdaSa1, site-specific recombinase phage integrase family protein NP_687574.1 558826 R 208435 CDS NP_687575.1 22536724 1013350 complement(560028..560231) 1 NC_004116.1 similar to GP:2444082; identified by sequence similarity; hypothetical protein 560231 1013350 SAG0546 Streptococcus agalactiae 2603V/R hypothetical protein NP_687575.1 560028 R 208435 CDS NP_687576.1 22536725 1013351 complement(560334..560891) 1 NC_004116.1 hypothetical protein 560891 1013351 SAG0547 Streptococcus agalactiae 2603V/R hypothetical protein NP_687576.1 560334 R 208435 CDS NP_687577.1 22536726 1013352 complement(560893..561690) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00717; prophage LambdaSa1, repressor protein 561690 1013352 SAG0548 Streptococcus agalactiae 2603V/R prophage LambdaSa1, repressor protein NP_687577.1 560893 R 208435 CDS NP_687578.1 22536727 1013353 562051..562194 1 NC_004116.1 hypothetical protein 562194 1013353 SAG0549 Streptococcus agalactiae 2603V/R hypothetical protein NP_687578.1 562051 D 208435 CDS NP_687579.1 22536728 1013354 complement(562191..562415) 1 NC_004116.1 hypothetical protein 562415 1013354 SAG0550 Streptococcus agalactiae 2603V/R hypothetical protein NP_687579.1 562191 R 208435 CDS NP_687580.1 22536729 1013355 562474..562632 1 NC_004116.1 hypothetical protein 562632 1013355 SAG0551 Streptococcus agalactiae 2603V/R hypothetical protein NP_687580.1 562474 D 208435 CDS NP_687581.1 22536730 1013356 562662..562850 1 NC_004116.1 hypothetical protein 562850 1013356 SAG0552 Streptococcus agalactiae 2603V/R hypothetical protein NP_687581.1 562662 D 208435 CDS NP_687582.1 22536731 1013357 complement(562833..563639) 1 NC_004116.1 hypothetical protein 563639 1013357 SAG0553 Streptococcus agalactiae 2603V/R hypothetical protein NP_687582.1 562833 R 208435 CDS NP_687583.1 22536732 1013358 563691..563882 1 NC_004116.1 identified by match to PFAM protein family HMM PF01381; prophage LambdaSa1, Cro/CI family transcriptional regulator 563882 1013358 SAG0554 Streptococcus agalactiae 2603V/R prophage LambdaSa1, Cro/CI family transcriptional regulator NP_687583.1 563691 D 208435 CDS NP_687584.1 22536733 1013359 563950..564699 1 NC_004116.1 prophage LambdaSa1, antirepressor 564699 1013359 SAG0555 Streptococcus agalactiae 2603V/R prophage LambdaSa1, antirepressor NP_687584.1 563950 D 208435 CDS NP_687585.1 22536734 1013360 564711..564854 1 NC_004116.1 hypothetical protein 564854 1013360 SAG0556 Streptococcus agalactiae 2603V/R hypothetical protein NP_687585.1 564711 D 208435 CDS NP_687586.1 22536735 1013361 565004..565234 1 NC_004116.1 hypothetical protein 565234 1013361 SAG0557 Streptococcus agalactiae 2603V/R hypothetical protein NP_687586.1 565004 D 208435 CDS NP_687587.1 22536736 1013362 565372..565596 1 NC_004116.1 hypothetical protein 565596 1013362 SAG0558 Streptococcus agalactiae 2603V/R hypothetical protein NP_687587.1 565372 D 208435 CDS NP_687588.1 22536737 1013363 565607..566467 1 NC_004116.1 hypothetical protein 566467 1013363 SAG0559 Streptococcus agalactiae 2603V/R hypothetical protein NP_687588.1 565607 D 208435 CDS NP_687589.1 22536738 1013364 566448..566681 1 NC_004116.1 hypothetical protein 566681 1013364 SAG0560 Streptococcus agalactiae 2603V/R hypothetical protein NP_687589.1 566448 D 208435 CDS NP_687590.1 22536739 1013365 566678..566818 1 NC_004116.1 hypothetical protein 566818 1013365 SAG0561 Streptococcus agalactiae 2603V/R hypothetical protein NP_687590.1 566678 D 208435 CDS NP_687591.1 22536740 1013366 566829..567083 1 NC_004116.1 hypothetical protein 567083 1013366 SAG0562 Streptococcus agalactiae 2603V/R hypothetical protein NP_687591.1 566829 D 208435 CDS NP_687592.1 22536741 1013367 567086..567247 1 NC_004116.1 hypothetical protein 567247 1013367 SAG0563 Streptococcus agalactiae 2603V/R hypothetical protein NP_687592.1 567086 D 208435 CDS NP_687593.1 22536742 1013368 567249..567731 1 NC_004116.1 hypothetical protein 567731 1013368 SAG0564 Streptococcus agalactiae 2603V/R hypothetical protein NP_687593.1 567249 D 208435 CDS NP_687594.1 22536743 1013369 567732..568406 1 NC_004116.1 similar to GP:8918764; identified by sequence similarity; hypothetical protein 568406 1013369 SAG0565 Streptococcus agalactiae 2603V/R hypothetical protein NP_687594.1 567732 D 208435 CDS NP_687595.1 22536744 1013370 568399..568815 1 NC_004116.1 identified by match to PFAM protein family HMM PF00436; prophage LambdaSa1, single-strand binding protein 568815 ssb-2 1013370 ssb-2 Streptococcus agalactiae 2603V/R prophage LambdaSa1, single-strand binding protein NP_687595.1 568399 D 208435 CDS NP_687596.1 22536745 1013371 569396..570715 1 NC_004116.1 identified by match to PFAM protein family HMM PF00078; prophage LambdaSa1, reverse transcriptase/maturase family protein 570715 1013371 SAG0567 Streptococcus agalactiae 2603V/R prophage LambdaSa1, reverse transcriptase/maturase family protein NP_687596.1 569396 D 208435 CDS NP_687597.1 22536746 1013372 570841..571044 1 NC_004116.1 hypothetical protein 571044 1013372 SAG0568 Streptococcus agalactiae 2603V/R hypothetical protein NP_687597.1 570841 D 208435 CDS NP_687598.1 22536747 1013373 571034..571510 1 NC_004116.1 hypothetical protein 571510 1013373 SAG0569 Streptococcus agalactiae 2603V/R hypothetical protein NP_687598.1 571034 D 208435 CDS NP_687599.1 22536748 1013374 571500..571847 1 NC_004116.1 hypothetical protein 571847 1013374 SAG0570 Streptococcus agalactiae 2603V/R hypothetical protein NP_687599.1 571500 D 208435 CDS YP_008592386.1 545902392 17097509 571859..572161 1 NC_004116.1 hypothetical protein 572161 17097509 SAG_RS02245 Streptococcus agalactiae 2603V/R hypothetical protein YP_008592386.1 571859 D 208435 CDS NP_687600.1 22536749 1013375 572165..572296 1 NC_004116.1 hypothetical protein 572296 1013375 SAG0571 Streptococcus agalactiae 2603V/R hypothetical protein NP_687600.1 572165 D 208435 CDS NP_687601.1 22536750 1013376 572296..572712 1 NC_004116.1 hypothetical protein 572712 1013376 SAG0572 Streptococcus agalactiae 2603V/R hypothetical protein NP_687601.1 572296 D 208435 CDS NP_687602.1 22536751 1013377 572709..572873 1 NC_004116.1 hypothetical protein 572873 1013377 SAG0573 Streptococcus agalactiae 2603V/R hypothetical protein NP_687602.1 572709 D 208435 CDS NP_687603.1 22536752 1013378 572870..573139 1 NC_004116.1 hypothetical protein 573139 1013378 SAG0574 Streptococcus agalactiae 2603V/R hypothetical protein NP_687603.1 572870 D 208435 CDS NP_687604.1 22536753 1013379 573142..573474 1 NC_004116.1 hypothetical protein 573474 1013379 SAG0575 Streptococcus agalactiae 2603V/R hypothetical protein NP_687604.1 573142 D 208435 CDS NP_687605.1 22536754 1013380 573557..573688 1 NC_004116.1 hypothetical protein 573688 1013380 SAG0576 Streptococcus agalactiae 2603V/R hypothetical protein NP_687605.1 573557 D 208435 CDS NP_687606.1 22536755 1013381 573781..574314 1 NC_004116.1 hypothetical protein 574314 1013381 SAG0577 Streptococcus agalactiae 2603V/R hypothetical protein NP_687606.1 573781 D 208435 CDS NP_687607.1 22536756 1013382 574311..574577 1 NC_004116.1 hypothetical protein 574577 1013382 SAG0578 Streptococcus agalactiae 2603V/R hypothetical protein NP_687607.1 574311 D 208435 CDS NP_687608.1 22536757 1013383 574965..575393 1 NC_004116.1 hypothetical protein 575393 1013383 SAG0579 Streptococcus agalactiae 2603V/R hypothetical protein NP_687608.1 574965 D 208435 CDS NP_687609.1 22536758 1013385 576505..576861 1 NC_004116.1 hypothetical protein 576861 1013385 SAG0581 Streptococcus agalactiae 2603V/R hypothetical protein NP_687609.1 576505 D 208435 CDS NP_687610.1 22536759 1013386 576858..578126 1 NC_004116.1 hypothetical protein 578126 1013386 SAG0582 Streptococcus agalactiae 2603V/R hypothetical protein NP_687610.1 576858 D 208435 CDS NP_687611.1 22536760 1013387 578119..579339 1 NC_004116.1 hypothetical protein 579339 1013387 SAG0583 Streptococcus agalactiae 2603V/R hypothetical protein NP_687611.1 578119 D 208435 CDS NP_687612.1 22536761 1013389 579635..581050 1 NC_004116.1 hypothetical protein 581050 1013389 SAG0585 Streptococcus agalactiae 2603V/R hypothetical protein NP_687612.1 579635 D 208435 CDS NP_687613.1 22536762 1013390 581131..581595 1 NC_004116.1 hypothetical protein 581595 1013390 SAG0586 Streptococcus agalactiae 2603V/R hypothetical protein NP_687613.1 581131 D 208435 CDS NP_687614.1 22536763 1013391 581598..582500 1 NC_004116.1 similar to PID:1353548; identified by sequence similarity; prophage LambdaSa1, structural protein 582500 1013391 SAG0587 Streptococcus agalactiae 2603V/R prophage LambdaSa1, structural protein NP_687614.1 581598 D 208435 CDS NP_687615.1 22536764 1013392 582497..582712 1 NC_004116.1 hypothetical protein 582712 1013392 SAG0588 Streptococcus agalactiae 2603V/R hypothetical protein NP_687615.1 582497 D 208435 CDS NP_687616.1 22536765 1013393 582726..583157 1 NC_004116.1 hypothetical protein 583157 1013393 SAG0589 Streptococcus agalactiae 2603V/R hypothetical protein NP_687616.1 582726 D 208435 CDS NP_687617.1 22536766 1013394 583108..583446 1 NC_004116.1 hypothetical protein 583446 1013394 SAG0590 Streptococcus agalactiae 2603V/R hypothetical protein NP_687617.1 583108 D 208435 CDS NP_687618.1 22536767 1013395 583439..583675 1 NC_004116.1 hypothetical protein 583675 1013395 SAG0591 Streptococcus agalactiae 2603V/R hypothetical protein NP_687618.1 583439 D 208435 CDS NP_687619.1 22536768 1013396 583676..584011 1 NC_004116.1 hypothetical protein 584011 1013396 SAG0592 Streptococcus agalactiae 2603V/R hypothetical protein NP_687619.1 583676 D 208435 CDS NP_687620.1 22536769 1013397 584021..584578 1 NC_004116.1 similar to PID:1353554; identified by sequence similarity; prophage LambdaSa1, structural protein 584578 1013397 SAG0593 Streptococcus agalactiae 2603V/R prophage LambdaSa1, structural protein NP_687620.1 584021 D 208435 CDS NP_687621.1 22536770 1013398 584578..584823 1 NC_004116.1 hypothetical protein 584823 1013398 SAG0594 Streptococcus agalactiae 2603V/R hypothetical protein NP_687621.1 584578 D 208435 CDS NP_687622.1 22536771 1013399 584838..585209 1 NC_004116.1 hypothetical protein 585209 1013399 SAG0595 Streptococcus agalactiae 2603V/R hypothetical protein NP_687622.1 584838 D 208435 CDS NP_687623.1 22536772 1013400 585209..587221 1 NC_004116.1 similar to GP:10732857; identified by sequence similarity; prophage LambdaSa1, pblA protein, internal deletion 587221 1013400 SAG0596 Streptococcus agalactiae 2603V/R prophage LambdaSa1, pblA protein, internal deletion NP_687623.1 585209 D 208435 CDS NP_687624.1 22536773 1013401 587215..588735 1 NC_004116.1 similar to GP:3540285; identified by sequence similarity; prophage LambdaSa1, minor structural protein 588735 1013401 SAG0597 Streptococcus agalactiae 2603V/R prophage LambdaSa1, minor structural protein NP_687624.1 587215 D 208435 CDS NP_687625.1 22536774 1013402 588736..592860 1 NC_004116.1 identified by match to PFAM protein family HMM PF01832; prophage LambdaSa1, N-acetylmuramoyl-L-alanine amidase family protein 592860 1013402 SAG0598 Streptococcus agalactiae 2603V/R prophage LambdaSa1, N-acetylmuramoyl-L-alanine amidase family protein NP_687625.1 588736 D 208435 CDS NP_687626.1 22536775 1013403 592871..594877 1 NC_004116.1 similar to GP:3540290; identified by sequence similarity; prophage LambdaSa1, minor structural protein 594877 1013403 SAG0599 Streptococcus agalactiae 2603V/R prophage LambdaSa1, minor structural protein NP_687626.1 592871 D 208435 CDS NP_687627.1 22536776 1013404 594903..595232 1 NC_004116.1 hypothetical protein 595232 1013404 SAG0600 Streptococcus agalactiae 2603V/R hypothetical protein NP_687627.1 594903 D 208435 CDS NP_687628.1 22536777 1013405 595207..595419 1 NC_004116.1 hypothetical protein 595419 1013405 SAG0601 Streptococcus agalactiae 2603V/R hypothetical protein NP_687628.1 595207 D 208435 CDS NP_687629.1 22536778 1013406 595432..595734 1 NC_004116.1 hypothetical protein 595734 1013406 SAG0602 Streptococcus agalactiae 2603V/R hypothetical protein NP_687629.1 595432 D 208435 CDS NP_687630.1 22536779 1013407 595736..596071 1 NC_004116.1 hypothetical protein 596071 1013407 SAG0603 Streptococcus agalactiae 2603V/R hypothetical protein NP_687630.1 595736 D 208435 CDS NP_687631.1 22536780 1013408 596073..596792 1 NC_004116.1 similar to GP:1934766; identified by sequence similarity; prophage LambdaSa1, lysin 596792 1013408 SAG0604 Streptococcus agalactiae 2603V/R prophage LambdaSa1, lysin NP_687631.1 596073 D 208435 CDS NP_687632.1 22536781 1013409 597125..598096 1 NC_004116.1 hypothetical protein 598096 1013409 SAG0605 Streptococcus agalactiae 2603V/R hypothetical protein NP_687632.1 597125 D 208435 CDS NP_687633.1 22536782 1013410 598200..598400 1 NC_004116.1 hypothetical protein 598400 1013410 SAG0606 Streptococcus agalactiae 2603V/R hypothetical protein NP_687633.1 598200 D 208435 CDS NP_687634.1 22536783 1013411 complement(598441..598611) 1 NC_004116.1 hypothetical protein 598611 1013411 SAG0607 Streptococcus agalactiae 2603V/R hypothetical protein NP_687634.1 598441 R 208435 CDS NP_687635.1 22536784 1013412 599028..599207 1 NC_004116.1 hypothetical protein 599207 1013412 SAG0608 Streptococcus agalactiae 2603V/R hypothetical protein NP_687635.1 599028 D 208435 CDS NP_687636.1 22536785 1013414 600190..600594 1 NC_004116.1 hypothetical protein 600594 1013414 SAG0610 Streptococcus agalactiae 2603V/R hypothetical protein NP_687636.1 600190 D 208435 CDS NP_687637.1 22536786 1013416 complement(601746..601907) 1 NC_004116.1 hypothetical protein 601907 1013416 SAG0612 Streptococcus agalactiae 2603V/R hypothetical protein NP_687637.1 601746 R 208435 CDS NP_687638.1 22536787 1013417 602649..603926 1 NC_004116.1 identified by match to PFAM protein family HMM PF02687; transmembrane protein Vexp1 603926 vex1 1013417 vex1 Streptococcus agalactiae 2603V/R transmembrane protein Vexp1 NP_687638.1 602649 D 208435 CDS NP_687639.1 22536788 1013418 603936..604592 1 NC_004116.1 identified by match to PFAM protein family HMM PF00005; ABC transporter ATP-binding protein 604592 vex2 1013418 vex2 Streptococcus agalactiae 2603V/R ABC transporter ATP-binding protein NP_687639.1 603936 D 208435 CDS NP_687640.1 22536789 1013419 604592..605968 1 NC_004116.1 identified by match to PFAM protein family HMM PF02687; transmembrane protein Vexp3 605968 vex3 1013419 vex3 Streptococcus agalactiae 2603V/R transmembrane protein Vexp3 NP_687640.1 604592 D 208435 CDS NP_687641.1 22536790 1013420 606065..606718 1 NC_004116.1 identified by match to PFAM protein family HMM PF00072; DNA-binding response regulator VncR 606718 vncR 1013420 vncR Streptococcus agalactiae 2603V/R DNA-binding response regulator VncR NP_687641.1 606065 D 208435 CDS NP_687642.1 22536791 1013421 606715..608034 1 NC_004116.1 identified by match to PFAM protein family HMM PF00512; sensor histidine kinase VncS 608034 vncS 1013421 vncS Streptococcus agalactiae 2603V/R sensor histidine kinase VncS NP_687642.1 606715 D 208435 CDS NP_687643.1 22536792 1013423 608911..609111 1 NC_004116.1 hypothetical protein 609111 1013423 SAG0619 Streptococcus agalactiae 2603V/R hypothetical protein NP_687643.1 608911 D 208435 CDS NP_687644.1 22536793 1013424 609153..609341 1 NC_004116.1 hypothetical protein 609341 1013424 SAG0620 Streptococcus agalactiae 2603V/R hypothetical protein NP_687644.1 609153 D 208435 CDS NP_687645.1 22536794 1013425 609766..610971 1 NC_004116.1 identified by match to PFAM protein family HMM PF01098; rod shape-determining protein RodA 610971 rodA 1013425 rodA Streptococcus agalactiae 2603V/R rod shape-determining protein RodA NP_687645.1 609766 D 208435 CDS NP_687646.1 22536795 1013426 611090..611650 1 NC_004116.1 identified by match to PFAM protein family HMM PF00702; HAD superfamily hydrolase 611650 1013426 SAG0622 Streptococcus agalactiae 2603V/R HAD superfamily hydrolase NP_687646.1 611090 D 208435 CDS NP_687647.1 22536796 1013427 611651..613603 1 NC_004116.1 negatively supercoils closed circular double-stranded DNA; DNA gyrase subunit B 613603 gyrB 1013427 gyrB Streptococcus agalactiae 2603V/R DNA gyrase subunit B NP_687647.1 611651 D 208435 CDS NP_687648.1 22536797 1013428 613697..615421 1 NC_004116.1 acts to negatively regulates ftsZ ring formation by modulating the frequency and position of the ftsZ ring formation; septation ring formation regulator EzrA 615421 1013428 SAG0624 Streptococcus agalactiae 2603V/R septation ring formation regulator EzrA NP_687648.1 613697 D 208435 CDS NP_687649.1 22536798 1013429 615515..616156 1 NC_004116.1 identified by match to PFAM protein family HMM PF00702; phosphoserine phosphatase SerB 616156 serB 1013429 serB Streptococcus agalactiae 2603V/R phosphoserine phosphatase SerB NP_687649.1 615515 D 208435 CDS NP_687650.1 22536799 1013430 complement(616177..616662) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00293; MutT/nudix family protein 616662 1013430 SAG0626 Streptococcus agalactiae 2603V/R MutT/nudix family protein NP_687650.1 616177 R 208435 CDS NP_687651.1 22536800 1013431 complement(616675..617130) 1 NC_004116.1 hypothetical protein 617130 1013431 SAG0627 Streptococcus agalactiae 2603V/R hypothetical protein NP_687651.1 616675 R 208435 CDS NP_687652.1 22536801 1013432 617328..618635 1 NC_004116.1 enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis; phosphopyruvate hydratase 618635 eno 1013432 eno Streptococcus agalactiae 2603V/R phosphopyruvate hydratase NP_687652.1 617328 D 208435 CDS NP_687653.1 22536802 1013433 complement(618743..619807) 1 NC_004116.1 similar to OMNI:NTL01SPL0534; identified by sequence similarity; hypothetical protein 619807 1013433 SAG0629 Streptococcus agalactiae 2603V/R hypothetical protein NP_687653.1 618743 R 208435 CDS NP_687654.1 22536803 1013434 620036..621319 1 NC_004116.1 catalyzes the formation of 5-O-(1-carboxyvinyl)-3-phosphoshikimate from phosphoenolpyruvate and 3-phosphoshikimate in tryptophan biosynthesis; 3-phosphoshikimate 1-carboxyvinyltransferase 621319 aroA 1013434 aroA Streptococcus agalactiae 2603V/R 3-phosphoshikimate 1-carboxyvinyltransferase NP_687654.1 620036 D 208435 CDS NP_687655.1 22536804 1013435 621312..621824 1 NC_004116.1 catalyzes the formation of shikimate 3-phosphate from shikimate in aromatic amino acid biosynthesis; shikimate kinase 621824 aroK 1013435 aroK Streptococcus agalactiae 2603V/R shikimate kinase NP_687655.1 621312 D 208435 CDS NP_687656.1 22536805 1013436 621881..623254 1 NC_004116.1 identified by match to TIGR protein family HMM TIGR00350; psr protein 623254 1013436 SAG0632 Streptococcus agalactiae 2603V/R psr protein NP_687656.1 621881 D 208435 CDS NP_687657.1 22536806 1013437 623355..624710 1 NC_004116.1 identified by match to PFAM protein family HMM PF01938; RNA methyltransferase 624710 1013437 SAG0633 Streptococcus agalactiae 2603V/R RNA methyltransferase NP_687657.1 623355 D 208435 CDS NP_687658.1 22536807 1013438 624827..625039 1 NC_004116.1 hypothetical protein 625039 1013438 SAG0634 Streptococcus agalactiae 2603V/R hypothetical protein NP_687658.1 624827 D 208435 CDS NP_687659.1 22536808 1013439 625157..625894 1 NC_004116.1 Class B; non-specific; catalyzes the dephosphorylation of organic phosphomonoesters; also has phosphotransferase activity; acid phosphatase/phosphotransferase 625894 aphA 1013439 aphA Streptococcus agalactiae 2603V/R acid phosphatase/phosphotransferase NP_687659.1 625157 D 208435 CDS NP_687660.1 22536809 1013440 626215..626733 1 NC_004116.1 hypothetical protein 626733 1013440 SAG0636 Streptococcus agalactiae 2603V/R hypothetical protein NP_687660.1 626215 D 208435 CDS NP_687661.1 22536810 1013443 complement(628019..628840) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00665; IS5 family transposase orfB 628840 1013443 SAG0639 Streptococcus agalactiae 2603V/R IS5 family transposase orfB NP_687661.1 628019 R 208435 CDS NP_687662.1 22536811 1013444 complement(628888..629163) 1 NC_004116.1 identified by match to PFAM protein family HMM PF01527; IS3 family transposase OrfA 629163 1013444 SAG0640 Streptococcus agalactiae 2603V/R IS3 family transposase OrfA NP_687662.1 628888 R 208435 CDS NP_687663.1 22536812 1013446 629519..629698 1 NC_004116.1 hypothetical protein 629698 1013446 SAG0642 Streptococcus agalactiae 2603V/R hypothetical protein NP_687663.1 629519 D 208435 CDS NP_687664.1 22536813 1013448 complement(630361..631569) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00165; AraC family transcriptional regulator 631569 1013448 SAG0644 Streptococcus agalactiae 2603V/R AraC family transcriptional regulator NP_687664.1 630361 R 208435 CDS NP_687665.1 22536814 1013449 631950..633614 1 NC_004116.1 identified by match to PFAM protein family HMM PF00746; The product of this gene was detected by Western blot analysis. For details on the method see Tettelin et al. 2002.; cell wall surface anchor family protein 633614 1013449 SAG0645 Streptococcus agalactiae 2603V/R cell wall surface anchor family protein NP_687665.1 631950 D 208435 CDS NP_687666.1 22536815 1013450 633703..634626 1 NC_004116.1 identified by match to TIGR protein family HMM TIGR01167; The product of this gene was detected by Western blot analysis. For details on the method see Tettelin et al. 2002.; cell wall surface anchor family protein 634626 1013450 SAG0646 Streptococcus agalactiae 2603V/R cell wall surface anchor family protein NP_687666.1 633703 D 208435 CDS NP_687667.1 22536816 1013451 634628..635545 1 NC_004116.1 identified by match to TIGR protein family HMM TIGR01076; sortase family protein 635545 1013451 SAG0647 Streptococcus agalactiae 2603V/R sortase family protein NP_687667.1 634628 D 208435 CDS NP_687668.1 22536817 1013452 635571..636353 1 NC_004116.1 identified by match to TIGR protein family HMM TIGR01076; sortase family protein 636353 1013452 SAG0648 Streptococcus agalactiae 2603V/R sortase family protein NP_687668.1 635571 D 208435 CDS NP_687669.1 22536818 1013453 636431..639103 1 NC_004116.1 similar to OMNI:SP0462; identified by sequence similarity; The product of this gene was detected by Western blot analysis. For details on the method see Tettelin et al. 2002.; cell wall surface anchor family protein 639103 1013453 SAG0649 Streptococcus agalactiae 2603V/R cell wall surface anchor family protein NP_687669.1 636431 D 208435 CDS NP_687670.1 22536819 1013454 639378..639947 1 NC_004116.1 identified by match to TIGR protein family HMM TIGR01076; sortase family protein 639947 1013454 SAG0650 Streptococcus agalactiae 2603V/R sortase family protein NP_687670.1 639378 D 208435 CDS NP_687671.1 22536820 1013455 640196..640801 1 NC_004116.1 identified by Glimmer2; The product of this gene was detected by Western blot analysis. For details on the method see Tettelin et al. 2002.; hypothetical protein 640801 1013455 SAG0651 Streptococcus agalactiae 2603V/R hypothetical protein NP_687671.1 640196 D 208435 CDS NP_687672.1 22536821 1013458 642197..642301 1 NC_004116.1 hypothetical protein 642301 1013458 SAG0654 Streptococcus agalactiae 2603V/R hypothetical protein NP_687672.1 642197 D 208435 CDS NP_687673.1 22536822 1013459 642734..642907 1 NC_004116.1 hypothetical protein 642907 1013459 SAG0655 Streptococcus agalactiae 2603V/R hypothetical protein NP_687673.1 642734 D 208435 CDS NP_687674.1 22536823 1013460 complement(643279..643389) 1 NC_004116.1 hypothetical protein 643389 1013460 SAG0656 Streptococcus agalactiae 2603V/R hypothetical protein NP_687674.1 643279 R 208435 CDS NP_687675.1 22536824 1013461 643420..643689 1 NC_004116.1 hypothetical protein 643689 1013461 SAG0657 Streptococcus agalactiae 2603V/R hypothetical protein NP_687675.1 643420 D 208435 CDS NP_687676.1 22536825 1013462 643750..644901 1 NC_004116.1 similar to OMNI:EF0746; identified by sequence similarity; lipoprotein 644901 1013462 SAG0658 Streptococcus agalactiae 2603V/R lipoprotein NP_687676.1 643750 D 208435 CDS NP_687677.1 22536826 1013463 645101..646093 1 NC_004116.1 identified by match to PFAM protein family HMM PF00005; ABC transporter ATP-binding protein 646093 1013463 SAG0659 Streptococcus agalactiae 2603V/R ABC transporter ATP-binding protein NP_687677.1 645101 D 208435 CDS NP_687678.1 22536827 1013464 646096..646914 1 NC_004116.1 similar to OMNI:SP0637; identified by sequence similarity; hypothetical protein 646914 1013464 SAG0660 Streptococcus agalactiae 2603V/R hypothetical protein NP_687678.1 646096 D 208435 CDS NP_687679.1 22536828 1013465 646916..647701 1 NC_004116.1 hypothetical protein 647701 1013465 SAG0661 Streptococcus agalactiae 2603V/R hypothetical protein NP_687679.1 646916 D 208435 CDS NP_687680.1 22536829 1013466 648326..648631 1 NC_004116.1 similar to GP:4886770; identified by sequence similarity; cylX protein 648631 1013466 SAG0662 Streptococcus agalactiae 2603V/R cylX protein NP_687680.1 648326 D 208435 CDS NP_687681.1 22536830 1013467 648631..649479 1 NC_004116.1 cylD protein 649479 cylD 1013467 cylD Streptococcus agalactiae 2603V/R cylD protein NP_687681.1 648631 D 208435 CDS NP_687682.1 22536831 1013468 649476..650198 1 NC_004116.1 identified by match to PFAM protein family HMM PF00106; cylG protein 650198 cylG 1013468 cylG Streptococcus agalactiae 2603V/R cylG protein NP_687682.1 649476 D 208435 CDS NP_687683.1 22536832 1013469 650191..650496 1 NC_004116.1 acyl carrier protein 650496 1013469 SAG0665 Streptococcus agalactiae 2603V/R acyl carrier protein NP_687683.1 650191 D 208435 CDS NP_687684.1 22536833 1013470 650480..650956 1 NC_004116.1 identified by match to PFAM protein family HMM PF01377; cylZ protein 650956 1013470 SAG0666 Streptococcus agalactiae 2603V/R cylZ protein NP_687684.1 650480 D 208435 CDS NP_687685.1 22536834 1013471 650946..651875 1 NC_004116.1 identified by match to PFAM protein family HMM PF00005; cylA protein 651875 cylA 1013471 cylA Streptococcus agalactiae 2603V/R cylA protein NP_687685.1 650946 D 208435 CDS NP_687686.1 22536835 1013472 651868..652746 1 NC_004116.1 cylB protein 652746 cylB 1013472 cylB Streptococcus agalactiae 2603V/R cylB protein NP_687686.1 651868 D 208435 CDS NP_687687.1 22536836 1013473 652743..654746 1 NC_004116.1 similar to GP:4886777; identified by sequence similarity; cylE protein 654746 cylE 1013473 cylE Streptococcus agalactiae 2603V/R cylE protein NP_687687.1 652743 D 208435 CDS NP_687688.1 22536837 1013474 654743..655696 1 NC_004116.1 identified by match to PFAM protein family HMM PF01571; cylF protein 655696 cylF 1013474 cylF Streptococcus agalactiae 2603V/R cylF protein NP_687688.1 654743 D 208435 CDS NP_687689.1 22536838 1013475 655693..657888 1 NC_004116.1 identified by match to PFAM protein family HMM PF00109; cylI protein 657888 cylI 1013475 cylI Streptococcus agalactiae 2603V/R cylI protein NP_687689.1 655693 D 208435 CDS NP_687690.1 22536839 1013476 657893..659104 1 NC_004116.1 similar to GP:6007854; identified by sequence similarity; cylJ protein 659104 cylJ 1013476 cylJ Streptococcus agalactiae 2603V/R cylJ protein NP_687690.1 657893 D 208435 CDS NP_687691.1 22536840 1013477 659073..659648 1 NC_004116.1 similar to GP:6007855; identified by sequence similarity; cylK protein 659648 cylK 1013477 cylK Streptococcus agalactiae 2603V/R cylK protein NP_687691.1 659073 D 208435 CDS NP_687692.1 22536841 1013478 659991..660332 1 NC_004116.1 hypothetical protein 660332 1013478 SAG0674 Streptococcus agalactiae 2603V/R hypothetical protein NP_687692.1 659991 D 208435 CDS NP_687693.1 22536842 1013479 660366..660881 1 NC_004116.1 similar to SP:P16952; identified by sequence similarity; secreted protein 660881 1013479 SAG0675 Streptococcus agalactiae 2603V/R secreted protein NP_687693.1 660366 D 208435 CDS NP_687694.1 22536843 1013480 660933..663590 1 NC_004116.1 identified by match to PFAM protein family HMM PF00082; proteinase 663590 1013480 SAG0676 Streptococcus agalactiae 2603V/R proteinase NP_687694.1 660933 D 208435 CDS NP_687695.1 22536844 1013481 663693..666881 1 NC_004116.1 identified by Glimmer2; The product of this gene was detected by Western blot analysis. For details on the method see Tettelin et al. 2002.; hypothetical protein 666881 1013481 SAG0677 Streptococcus agalactiae 2603V/R hypothetical protein NP_687695.1 663693 D 208435 CDS NP_687696.1 22536845 1013483 669128..670159 1 NC_004116.1 The product of this gene was detected by Western blot analysis. For details on the method see Tettelin et al. 2002.; hypothetical protein 670159 1013483 SAG0679 Streptococcus agalactiae 2603V/R hypothetical protein NP_687696.1 669128 D 208435 CDS NP_687697.1 22536846 1013484 670194..671213 1 NC_004116.1 The product of this gene was detected by Western blot analysis. For details on the method see Tettelin et al. 2002.; hypothetical protein 671213 1013484 SAG0680 Streptococcus agalactiae 2603V/R hypothetical protein NP_687697.1 670194 D 208435 CDS NP_687698.1 22536847 1013485 671248..672309 1 NC_004116.1 hypothetical protein 672309 1013485 SAG0681 Streptococcus agalactiae 2603V/R hypothetical protein NP_687698.1 671248 D 208435 CDS NP_687699.1 22536848 1013486 672433..673662 1 NC_004116.1 identified by match to PFAM protein family HMM PF02687; permease 673662 1013486 SAG0682 Streptococcus agalactiae 2603V/R permease NP_687699.1 672433 D 208435 CDS NP_687700.1 22536849 1013488 675121..675792 1 NC_004116.1 identified by match to PFAM protein family HMM PF00005; ABC transporter ATP-binding protein 675792 1013488 SAG0684 Streptococcus agalactiae 2603V/R ABC transporter ATP-binding protein NP_687700.1 675121 D 208435 CDS NP_687701.1 22536850 1013489 complement(675849..677267) 1 NC_004116.1 hypothetical protein 677267 1013489 SAG0685 Streptococcus agalactiae 2603V/R hypothetical protein NP_687701.1 675849 R 208435 CDS NP_687702.1 22536851 1013490 677555..678340 1 NC_004116.1 similar to SP:Q03158 GB:X54225 PID:47374; identified by sequence similarity; DNA-entry nuclease 678340 1013490 SAG0686 Streptococcus agalactiae 2603V/R DNA-entry nuclease NP_687702.1 677555 D 208435 CDS NP_687703.1 22536852 1013491 complement(678418..679056) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00597; DedA family protein 679056 1013491 SAG0687 Streptococcus agalactiae 2603V/R DedA family protein NP_687703.1 678418 R 208435 CDS NP_687704.1 22536853 1013492 679273..679929 1 NC_004116.1 identified by match to PFAM protein family HMM PF00005; ABC transporter ATP-binding protein 679929 1013492 SAG0688 Streptococcus agalactiae 2603V/R ABC transporter ATP-binding protein NP_687704.1 679273 D 208435 CDS NP_687705.1 22536854 1013493 679926..680699 1 NC_004116.1 identified by match to TIGR protein family HMM TIGR00245; hypothetical protein 680699 1013493 SAG0689 Streptococcus agalactiae 2603V/R hypothetical protein NP_687705.1 679926 D 208435 CDS NP_687706.1 22536855 1013494 680863..681681 1 NC_004116.1 hypothetical protein 681681 1013494 SAG0690 Streptococcus agalactiae 2603V/R hypothetical protein NP_687706.1 680863 D 208435 CDS NP_687707.1 22536856 1013495 complement(681718..682602) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00126; LysR family transcriptional regulator 682602 1013495 SAG0691 Streptococcus agalactiae 2603V/R LysR family transcriptional regulator NP_687707.1 681718 R 208435 CDS NP_687708.1 22536857 1013496 682795..683376 1 NC_004116.1 similar to GP:5901699; identified by sequence similarity; regulatory protein 683376 1013496 SAG0692 Streptococcus agalactiae 2603V/R regulatory protein NP_687708.1 682795 D 208435 CDS NP_687709.1 22536858 1013497 complement(683390..684523) 1 NC_004116.1 identified by match to PFAM protein family HMM PF01609; IS1548 transposase 684523 1013497 SAG0693 Streptococcus agalactiae 2603V/R IS1548 transposase NP_687709.1 683390 R 208435 CDS NP_687710.1 22536859 1013499 685192..686184 1 NC_004116.1 catalyzes the formation of pyruvate from lactate; D-lactate dehydrogenase 686184 ldhA 1013499 ldhA Streptococcus agalactiae 2603V/R D-lactate dehydrogenase NP_687710.1 685192 D 208435 CDS NP_687711.1 22536860 1013500 686391..687941 1 NC_004116.1 sugar transporter 687941 1013500 SAG0696 Streptococcus agalactiae 2603V/R sugar transporter NP_687711.1 686391 D 208435 CDS NP_687712.1 22536861 1013501 688008..689033 1 NC_004116.1 identified by match to PFAM protein family HMM PF00294; 2-keto-3-deoxygluconate kinase 689033 1013501 SAG0697 Streptococcus agalactiae 2603V/R 2-keto-3-deoxygluconate kinase NP_687712.1 688008 D 208435 CDS NP_687713.1 22536862 1013502 689050..690849 1 NC_004116.1 identified by match to PFAM protein family HMM PF00703; beta-D-glucuronidase 690849 1013502 SAG0698 Streptococcus agalactiae 2603V/R beta-D-glucuronidase NP_687713.1 689050 D 208435 CDS NP_687714.1 22536863 1013503 690878..691549 1 NC_004116.1 identified by match to PFAM protein family HMM PF00392; GntR family transcriptional regulator 691549 1013503 SAG0699 Streptococcus agalactiae 2603V/R GntR family transcriptional regulator NP_687714.1 690878 D 208435 CDS NP_687715.1 22536864 1013504 691666..692283 1 NC_004116.1 identified by match to PFAM protein family HMM PF01081; 2-dehydro-3-deoxyphosphooctonate aldolase 692283 eda-1 1013504 eda-1 Streptococcus agalactiae 2603V/R 2-dehydro-3-deoxyphosphooctonate aldolase NP_687715.1 691666 D 208435 CDS NP_687716.1 22536865 1013505 692300..693700 1 NC_004116.1 catalyzes the interconversion of D-glucuronate to D-fructuronate or D-galacturonate to D-tagaturonate; functions in glucuronic and galacturonic metabolism; glucuronate isomerase 693700 uxaC 1013505 uxaC Streptococcus agalactiae 2603V/R glucuronate isomerase NP_687716.1 692300 D 208435 CDS NP_687717.1 22536866 1013506 693718..694764 1 NC_004116.1 catalyzes the formation of 2-dehydro-3-deoxy-D-gluconate from mannonate; mannonate dehydratase 694764 uxuA 1013506 uxuA Streptococcus agalactiae 2603V/R mannonate dehydratase NP_687717.1 693718 D 208435 CDS NP_687718.1 22536867 1013507 694888..695727 1 NC_004116.1 Converts D-mannonate to D-mannuronate; D-mannonate oxidoreductase 695727 1013507 SAG0703 Streptococcus agalactiae 2603V/R D-mannonate oxidoreductase NP_687718.1 694888 D 208435 CDS NP_687719.1 22536868 1013508 695880..696692 1 NC_004116.1 identified by match to PFAM protein family HMM PF00702; HAD superfamily hydrolase 696692 1013508 SAG0704 Streptococcus agalactiae 2603V/R HAD superfamily hydrolase NP_687719.1 695880 D 208435 CDS NP_687720.1 22536869 1013509 696708..698498 1 NC_004116.1 identified by match to PFAM protein family HMM PF00933; glycosyl hydrolase family protein 698498 1013509 SAG0705 Streptococcus agalactiae 2603V/R glycosyl hydrolase family protein NP_687720.1 696708 D 208435 CDS NP_687721.1 22536870 1013510 complement(698556..699641) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00557; proline dipeptidase 699641 pepQ 1013510 pepQ Streptococcus agalactiae 2603V/R proline dipeptidase NP_687721.1 698556 R 208435 CDS NP_687722.1 22536871 1013511 699851..700855 1 NC_004116.1 identified by match to PFAM protein family HMM PF00356; RegM family transcriptional regulator 700855 1013511 SAG0707 Streptococcus agalactiae 2603V/R RegM family transcriptional regulator NP_687722.1 699851 D 208435 CDS NP_687723.1 22536872 1013512 700987..702453 1 NC_004116.1 converts 1,4-alpha-D-glucans to maltodextrin; alpha-amylase 702453 1013512 SAG0708 Streptococcus agalactiae 2603V/R alpha-amylase NP_687723.1 700987 D 208435 CDS NP_687724.1 22536873 1013513 702498..703496 1 NC_004116.1 identified by match to PFAM protein family HMM PF00534; glycoside hydrolase family protein 703496 1013513 SAG0709 Streptococcus agalactiae 2603V/R glycoside hydrolase family protein NP_687724.1 702498 D 208435 CDS NP_687725.1 22536874 1013514 703498..704832 1 NC_004116.1 identified by match to PFAM protein family HMM PF00534; glycoside hydrolase family protein 704832 1013514 SAG0710 Streptococcus agalactiae 2603V/R glycoside hydrolase family protein NP_687725.1 703498 D 208435 CDS NP_687726.1 22536875 1013515 705289..707232 1 NC_004116.1 catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr); threonyl-tRNA synthetase 707232 thrS 1013515 thrS Streptococcus agalactiae 2603V/R threonyl-tRNA synthetase NP_687726.1 705289 D 208435 CDS NP_687727.1 22536876 1013516 707454..708158 1 NC_004116.1 identified by match to PFAM protein family HMM PF00072; DNA-binding response regulator 708158 1013516 SAG0712 Streptococcus agalactiae 2603V/R DNA-binding response regulator NP_687727.1 707454 D 208435 CDS NP_687728.1 22536877 1013517 708256..709275 1 NC_004116.1 hypothetical protein 709275 1013517 SAG0713 Streptococcus agalactiae 2603V/R hypothetical protein NP_687728.1 708256 D 208435 CDS NP_687729.1 22536878 1013518 709443..710009 1 NC_004116.1 hypothetical protein 710009 1013518 SAG0714 Streptococcus agalactiae 2603V/R hypothetical protein NP_687729.1 709443 D 208435 CDS NP_687730.1 22536879 1013519 complement(710058..710708) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00528; amino acid ABC transporter permease 710708 1013519 SAG0715 Streptococcus agalactiae 2603V/R amino acid ABC transporter permease NP_687730.1 710058 R 208435 CDS NP_687731.1 22536880 1013520 complement(710720..711415) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00528; amino acid ABC transporter permease 711415 1013520 SAG0716 Streptococcus agalactiae 2603V/R amino acid ABC transporter permease NP_687731.1 710720 R 208435 CDS NP_687732.1 22536881 1013521 complement(711428..712228) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00497; amino acid ABC transporter amino acid-binding protein 712228 1013521 SAG0717 Streptococcus agalactiae 2603V/R amino acid ABC transporter amino acid-binding protein NP_687732.1 711428 R 208435 CDS NP_687733.1 22536882 1013522 complement(712240..712995) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00005; amino acid ABC transporter ATP-binding protein 712995 1013522 SAG0718 Streptococcus agalactiae 2603V/R amino acid ABC transporter ATP-binding protein NP_687733.1 712240 R 208435 CDS NP_687734.1 22536883 1013523 713335..714045 1 NC_004116.1 identified by match to PFAM protein family HMM PF00072; DNA-binding response regulator 714045 1013523 SAG0719 Streptococcus agalactiae 2603V/R DNA-binding response regulator NP_687734.1 713335 D 208435 CDS NP_687735.1 22536884 1013524 714038..715387 1 NC_004116.1 identified by match to PFAM protein family HMM PF00512; sensory box histidine kinase 715387 1013524 SAG0720 Streptococcus agalactiae 2603V/R sensory box histidine kinase NP_687735.1 714038 D 208435 CDS NP_687736.1 22536885 1013525 715391..716200 1 NC_004116.1 identified by match to PFAM protein family HMM PF00753; metallo-beta-lactamase superfamily protein 716200 1013525 SAG0721 Streptococcus agalactiae 2603V/R metallo-beta-lactamase superfamily protein NP_687736.1 715391 D 208435 CDS NP_687737.1 22536886 1013526 716203..716571 1 NC_004116.1 hypothetical protein 716571 1013526 SAG0722 Streptococcus agalactiae 2603V/R hypothetical protein NP_687737.1 716203 D 208435 CDS NP_687738.1 22536887 1013527 716723..717433 1 NC_004116.1 cytoplasmic enzyme involved in processing rRNA and some mRNAs; substrates typically have dsRNA regions; forms a homodimer; have N-terminal nuclease and C-terminal RNA-binding domains; requires magnesium as preferred ion for activity; ribonuclease III 717433 rnc 1013527 rnc Streptococcus agalactiae 2603V/R ribonuclease III NP_687738.1 716723 D 208435 CDS NP_687739.1 22536888 1013528 717441..720980 1 NC_004116.1 identified by match to PFAM protein family HMM PF02463; The product of this gene was detected by Western blot analysis. For details on the method see Tettelin et al. 2002.; chromosome segregation protein SMC 720980 1013528 SAG0724 Streptococcus agalactiae 2603V/R chromosome segregation protein SMC NP_687739.1 717441 D 208435 CDS NP_687740.1 22536889 1013529 721071..721868 1 NC_004116.1 identified by match to PFAM protein family HMM PF00702; HAD superfamily hydrolase 721868 1013529 SAG0725 Streptococcus agalactiae 2603V/R HAD superfamily hydrolase NP_687740.1 721071 D 208435 CDS NP_687741.1 22536890 1013530 721868..722692 1 NC_004116.1 identified by match to PFAM protein family HMM PF00702; HAD superfamily hydrolase 722692 1013530 SAG0726 Streptococcus agalactiae 2603V/R HAD superfamily hydrolase NP_687741.1 721868 D 208435 CDS NP_687742.1 22536891 1013531 722692..724302 1 NC_004116.1 identified by match to PFAM protein family HMM PF00448; signal recognition particle-docking protein FtsY 724302 ftsY 1013531 ftsY Streptococcus agalactiae 2603V/R signal recognition particle-docking protein FtsY NP_687742.1 722692 D 208435 CDS NP_687743.1 22536892 1013532 complement(724339..725151) 1 NC_004116.1 similar to OMNI:NTL01SPL0427; identified by sequence similarity; hypothetical protein 725151 1013532 SAG0728 Streptococcus agalactiae 2603V/R hypothetical protein NP_687743.1 724339 R 208435 CDS NP_687744.1 22536893 1013533 complement(725151..726053) 1 NC_004116.1 similar to OMNI:NTL01SPL0428; identified by sequence similarity; ABC transporter permease 726053 1013533 SAG0729 Streptococcus agalactiae 2603V/R ABC transporter permease NP_687744.1 725151 R 208435 CDS NP_687745.1 22536894 1013534 complement(726059..726187) 1 NC_004116.1 similar to OMNI:NTL01SPL0429; identified by sequence similarity; hypothetical protein 726187 1013534 SAG0730 Streptococcus agalactiae 2603V/R hypothetical protein NP_687745.1 726059 R 208435 CDS NP_687746.1 22536895 1013535 726320..727363 1 NC_004116.1 identified by match to PFAM protein family HMM PF00296; luciferase family protein 727363 1013535 SAG0731 Streptococcus agalactiae 2603V/R luciferase family protein NP_687746.1 726320 D 208435 CDS NP_687747.1 22536896 1013536 727468..729630 1 NC_004116.1 identified by match to PFAM protein family HMM PF00575; transcriptional accessory protein Tex 729630 1013536 SAG0732 Streptococcus agalactiae 2603V/R transcriptional accessory protein Tex NP_687747.1 727468 D 208435 CDS NP_687748.1 22536897 1013537 729623..730051 1 NC_004116.1 hypothetical protein 730051 1013537 SAG0733 Streptococcus agalactiae 2603V/R hypothetical protein NP_687748.1 729623 D 208435 CDS NP_687749.1 22536898 1013538 730132..730395 1 NC_004116.1 similar to SP:P23855 GB:X57560 PID:42541 GB:U00096 PID:1742136; identified by sequence similarity; phage shock protein C 730395 1013538 SAG0734 Streptococcus agalactiae 2603V/R phage shock protein C NP_687749.1 730132 D 208435 CDS NP_687750.1 22536899 1013539 730373..730507 1 NC_004116.1 hypothetical protein 730507 1013539 SAG0735 Streptococcus agalactiae 2603V/R hypothetical protein NP_687750.1 730373 D 208435 CDS NP_687751.1 22536900 1013540 730623..731558 1 NC_004116.1 catalyzes the phosphorylation of the phosphocarrier protein HPr of the bacterial phosphotransferase system; HPr kinase/phosphorylase 731558 hprK 1013540 hprK Streptococcus agalactiae 2603V/R HPr kinase/phosphorylase NP_687751.1 730623 D 208435 CDS NP_687752.1 22536901 1013541 731551..732324 1 NC_004116.1 transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein; prolipoprotein diacylglyceryl transferase 732324 lgt 1013541 lgt Streptococcus agalactiae 2603V/R prolipoprotein diacylglyceryl transferase NP_687752.1 731551 D 208435 CDS NP_687753.1 22536902 1013542 732339..732737 1 NC_004116.1 hypothetical protein 732737 1013542 SAG0738 Streptococcus agalactiae 2603V/R hypothetical protein NP_687753.1 732339 D 208435 CDS NP_687754.1 22536903 1013543 732734..733165 1 NC_004116.1 hypothetical protein 733165 1013543 SAG0739 Streptococcus agalactiae 2603V/R hypothetical protein NP_687754.1 732734 D 208435 CDS NP_687755.1 22536904 1013544 complement(733206..733481) 1 NC_004116.1 hypothetical protein 733481 1013544 SAG0740 Streptococcus agalactiae 2603V/R hypothetical protein NP_687755.1 733206 R 208435 CDS NP_687756.1 22536905 1013545 733836..734747 1 NC_004116.1 hypothetical protein 734747 1013545 SAG0741 Streptococcus agalactiae 2603V/R hypothetical protein NP_687756.1 733836 D 208435 CDS NP_687757.1 22536906 1013546 734877..736163 1 NC_004116.1 identified by match to PFAM protein family HMM PF01136; U32 family peptidase 736163 1013546 SAG0742 Streptococcus agalactiae 2603V/R U32 family peptidase NP_687757.1 734877 D 208435 CDS NP_687758.1 22536907 1013547 736290..736502 1 NC_004116.1 hypothetical protein 736502 1013547 SAG0743 Streptococcus agalactiae 2603V/R hypothetical protein NP_687758.1 736290 D 208435 CDS NP_687759.1 22536908 1013548 736626..737423 1 NC_004116.1 hypothetical protein 737423 1013548 SAG0744 Streptococcus agalactiae 2603V/R hypothetical protein NP_687759.1 736626 D 208435 CDS NP_687760.1 22536909 1013549 complement(737525..738865) 1 NC_004116.1 identified by match to PFAM protein family HMM PF01566; Mn2+/Fe2+ transporter 738865 1013549 SAG0745 Streptococcus agalactiae 2603V/R Mn2+/Fe2+ transporter NP_687760.1 737525 R 208435 CDS NP_687761.1 22536910 1013550 739594..740703 1 NC_004116.1 identified by match to PFAM protein family HMM PF00383; riboflavin biosynthesis protein RibD 740703 ribD 1013550 ribD Streptococcus agalactiae 2603V/R riboflavin biosynthesis protein RibD NP_687761.1 739594 D 208435 CDS NP_687762.2 161485615 1013551 740684..741334 1 NC_004116.1 catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine; riboflavin synthase subunit alpha 741334 ribE 1013551 ribE Streptococcus agalactiae 2603V/R riboflavin synthase subunit alpha NP_687762.2 740684 D 208435 CDS NP_687763.1 22536912 1013552 741352..742545 1 NC_004116.1 identified by match to PFAM protein family HMM PF00925; riboflavin biosynthesis protein RibA 742545 ribA 1013552 ribA Streptococcus agalactiae 2603V/R riboflavin biosynthesis protein RibA NP_687763.1 741352 D 208435 CDS NP_687764.1 22536913 1013553 742560..743030 1 NC_004116.1 RibE; 6,7-diimethyl-8-ribityllumazine synthase; DMRL synthase; lumazine synthase; beta subunit of riboflavin synthase; condenses 5-amino-6-(1'-D)-ribityl-amino-2,4(1H,3H)-pyrimidinedione with L-3,4-dihydrohy-2-butanone-4-phosphate to generate 6,6-dimethyl-8-lumazine (DMRL); riboflavin synthase then uses 2 molecules of DMRL to produce riboflavin (vitamin B12); involved in the last steps of riboflavin biosynthesis; forms a 60mer (icosahedral shell) in both Bacillus subtilis and Escherichia coli; in Bacillus subtilis this 60mer is associated with the riboflavin synthase subunit (alpha) while in Escherichia coli it is not; 6,7-dimethyl-8-ribityllumazine synthase 743030 ribH 1013553 ribH Streptococcus agalactiae 2603V/R 6,7-dimethyl-8-ribityllumazine synthase NP_687764.1 742560 D 208435 CDS NP_687765.1 22536914 1013554 complement(743105..744595) 1 NC_004116.1 class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1; lysyl-tRNA synthetase 744595 lysS 1013554 lysS Streptococcus agalactiae 2603V/R lysyl-tRNA synthetase NP_687765.1 743105 R 208435 CDS NP_687766.1 22536915 1013555 744770..745672 1 NC_004116.1 identified by match to PFAM protein family HMM PF00702; HAD superfamily hydrolase 745672 1013555 SAG0751 Streptococcus agalactiae 2603V/R HAD superfamily hydrolase NP_687766.1 744770 D 208435 CDS NP_687767.1 22536916 1013556 complement(745708..746349) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00300; phosphoglycerate mutase family protein 746349 1013556 SAG0752 Streptococcus agalactiae 2603V/R phosphoglycerate mutase family protein NP_687767.1 745708 R 208435 CDS NP_687768.1 22536917 1013557 complement(746371..746844) 1 NC_004116.1 EbsC family transcriptional regulator 746844 1013557 SAG0753 Streptococcus agalactiae 2603V/R EbsC family transcriptional regulator NP_687768.1 746371 R 208435 CDS NP_687769.1 22536918 1013558 747139..747756 1 NC_004116.1 hypothetical protein 747756 1013558 SAG0754 Streptococcus agalactiae 2603V/R hypothetical protein NP_687769.1 747139 D 208435 CDS NP_687770.1 22536919 1013559 complement(747789..748637) 1 NC_004116.1 similar to OMNI:NTL01SPL0447; identified by sequence similarity; U32 family peptidase 748637 1013559 SAG0755 Streptococcus agalactiae 2603V/R U32 family peptidase NP_687770.1 747789 R 208435 CDS NP_687771.1 22536920 1013560 748793..749317 1 NC_004116.1 hypothetical protein 749317 1013560 SAG0756 Streptococcus agalactiae 2603V/R hypothetical protein NP_687771.1 748793 D 208435 CDS NP_687772.1 22536921 1013561 749301..749690 1 NC_004116.1 similar to GP:13621804; identified by sequence similarity; The product of this gene was detected by Western blot analysis. For details on the method see Tettelin et al. 2002.; hypothetical protein 749690 1013561 SAG0757 Streptococcus agalactiae 2603V/R hypothetical protein NP_687772.1 749301 D 208435 CDS NP_687773.1 22536922 1013562 complement(749749..751548) 1 NC_004116.1 identified by match to PFAM protein family HMM PF01432; oligoendopeptidase F 751548 1013562 SAG0758 Streptococcus agalactiae 2603V/R oligoendopeptidase F NP_687773.1 749749 R 208435 CDS NP_687774.1 22536923 1013563 751757..754552 1 NC_004116.1 catalyzes the formation of oxaloacetate from phosphoenolpyruvate; phosphoenolpyruvate carboxylase 754552 ppc 1013563 ppc Streptococcus agalactiae 2603V/R phosphoenolpyruvate carboxylase NP_687774.1 751757 D 208435 CDS NP_687775.1 22536924 1013564 754678..755811 1 NC_004116.1 identified by match to PFAM protein family HMM PF01609; IS1548 transposase 755811 1013564 SAG0760 Streptococcus agalactiae 2603V/R IS1548 transposase NP_687775.1 754678 D 208435 CDS NP_687776.1 22536925 1013565 755984..757252 1 NC_004116.1 identified by match to PFAM protein family HMM PF01098; cell cycle protein FtsW 757252 ftsW 1013565 ftsW Streptococcus agalactiae 2603V/R cell cycle protein FtsW NP_687776.1 755984 D 208435 CDS NP_687777.1 22536926 1013566 757604..758800 1 NC_004116.1 EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu; elongation factor Tu 758800 tuf 1013566 tuf Streptococcus agalactiae 2603V/R elongation factor Tu NP_687777.1 757604 D 208435 CDS NP_687778.1 22536927 1013567 758981..759739 1 NC_004116.1 Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate; triosephosphate isomerase 759739 tpiA 1013567 tpiA Streptococcus agalactiae 2603V/R triosephosphate isomerase NP_687778.1 758981 D 208435 CDS NP_687779.1 22536928 1013568 759916..760608 1 NC_004116.1 2,3-bisphosphoglycerate-dependent; catalyzes the interconversion of 2-phosphoglycerate to 3-phosphoglycerate; phosphoglyceromutase 760608 gpmA 1013568 gpmA Streptococcus agalactiae 2603V/R phosphoglyceromutase NP_687779.1 759916 D 208435 CDS NP_687780.1 22536929 1013569 760737..762782 1 NC_004116.1 identified by match to PFAM protein family HMM PF00905; penicillin-binding protein 2b 762782 1013569 SAG0765 Streptococcus agalactiae 2603V/R penicillin-binding protein 2b NP_687780.1 760737 D 208435 CDS NP_687781.1 22536930 1013570 762797..763393 1 NC_004116.1 involved in a recombinational process of DNA repair, independent of the recBC complex; recombination protein RecR 763393 recR 1013570 recR Streptococcus agalactiae 2603V/R recombination protein RecR NP_687781.1 762797 D 208435 CDS NP_687782.1 22536931 1013571 763534..764580 1 NC_004116.1 D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli; D-alanyl-alanine synthetase A 764580 ddl 1013571 ddl Streptococcus agalactiae 2603V/R D-alanyl-alanine synthetase A NP_687782.1 763534 D 208435 CDS NP_687783.1 22536932 1013572 764727..766094 1 NC_004116.1 identified by match to PFAM protein family HMM PF01225; UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate--D-alanyl-D-alanyl ligase 766094 murF 1013572 murF Streptococcus agalactiae 2603V/R UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate--D-alanyl-D-alanyl ligase NP_687783.1 764727 D 208435 CDS NP_687784.1 22536933 1013573 766281..767501 1 NC_004116.1 identified by match to PFAM protein family HMM PF00083; oxalate:formate antiporter 767501 1013573 SAG0769 Streptococcus agalactiae 2603V/R oxalate:formate antiporter NP_687784.1 766281 D 208435 CDS NP_687785.1 22536934 1013574 767630..768316 1 NC_004116.1 similar to OMNI:SP1668; identified by sequence similarity; hypothetical protein 768316 1013574 SAG0770 Streptococcus agalactiae 2603V/R hypothetical protein NP_687785.1 767630 D 208435 CDS NP_687786.1 22536935 1013575 768495..770033 1 NC_004116.1 identified by match to TIGR protein family HMM TIGR01167; cell wall surface anchor family protein 770033 1013575 SAG0771 Streptococcus agalactiae 2603V/R cell wall surface anchor family protein NP_687786.1 768495 D 208435 CDS NP_687787.1 22536936 1013576 770210..771754 1 NC_004116.1 stimulates the release of release factors 1 and 2 from the ribosome after hydrolysis of the ester bond in peptidyl-tRNA has occurred; GDP/GTP-binding protein; peptide chain release factor 3 771754 prfC 1013576 prfC Streptococcus agalactiae 2603V/R peptide chain release factor 3 NP_687787.1 770210 D 208435 CDS NP_687788.1 22536937 1013577 771840..772220 1 NC_004116.1 hypothetical protein 772220 1013577 SAG0773 Streptococcus agalactiae 2603V/R hypothetical protein NP_687788.1 771840 D 208435 CDS NP_687789.1 22536938 1013578 772341..773075 1 NC_004116.1 identified by match to PFAM protein family HMM PF00005; ABC transporter ATP-binding protein 773075 1013578 SAG0774 Streptococcus agalactiae 2603V/R ABC transporter ATP-binding protein NP_687789.1 772341 D 208435 CDS NP_687790.1 22536939 1013579 773068..773730 1 NC_004116.1 identified by match to PFAM protein family HMM PF00528; ABC transporter permease 773730 1013579 SAG0775 Streptococcus agalactiae 2603V/R ABC transporter permease NP_687790.1 773068 D 208435 CDS NP_687791.1 22536940 1013580 773746..774576 1 NC_004116.1 identified by match to PFAM protein family HMM PF03180; YaeC family protein 774576 1013580 SAG0776 Streptococcus agalactiae 2603V/R YaeC family protein NP_687791.1 773746 D 208435 CDS NP_687792.1 22536941 1013581 774811..776397 1 NC_004116.1 identified by match to PFAM protein family HMM PF00270; DEAD/DEAH box helicase 776397 1013581 SAG0777 Streptococcus agalactiae 2603V/R DEAD/DEAH box helicase NP_687792.1 774811 D 208435 CDS NP_687793.1 22536942 1013582 complement(776582..776848) 1 NC_004116.1 hypothetical protein 776848 1013582 SAG0778 Streptococcus agalactiae 2603V/R hypothetical protein NP_687793.1 776582 R 208435 CDS NP_687794.1 22536943 1013583 complement(776841..777605) 1 NC_004116.1 hypothetical protein 777605 1013583 SAG0779 Streptococcus agalactiae 2603V/R hypothetical protein NP_687794.1 776841 R 208435 CDS NP_687795.1 22536944 1013584 777740..778480 1 NC_004116.1 identified by match to PFAM protein family HMM PF01553; acyltransferase 778480 1013584 SAG0780 Streptococcus agalactiae 2603V/R acyltransferase NP_687795.1 777740 D 208435 CDS NP_687796.1 22536945 1013585 778580..779233 1 NC_004116.1 identified by match to PFAM protein family HMM PF00633; competence protein CelA 779233 celA 1013585 celA Streptococcus agalactiae 2603V/R competence protein CelA NP_687796.1 778580 D 208435 CDS NP_687797.1 22536946 1013586 779217..781454 1 NC_004116.1 identified by match to PFAM protein family HMM PF00753; DNA internalization-related competence protein ComEC/Rec2 781454 1013586 SAG0782 Streptococcus agalactiae 2603V/R DNA internalization-related competence protein ComEC/Rec2 NP_687797.1 779217 D 208435 CDS NP_687798.1 22536947 1013587 781580..782389 1 NC_004116.1 identified by match to PFAM protein family HMM PF00702; HAD superfamily hydrolase 782389 1013587 SAG0783 Streptococcus agalactiae 2603V/R HAD superfamily hydrolase NP_687798.1 781580 D 208435 CDS NP_687799.1 22536948 1013588 782400..783344 1 NC_004116.1 identified by match to PFAM protein family HMM PF00356; LacI family sugar-binding transcriptional regulator 783344 1013588 SAG0784 Streptococcus agalactiae 2603V/R LacI family sugar-binding transcriptional regulator NP_687799.1 782400 D 208435 CDS NP_687800.1 22536949 1013589 complement(783403..784395) 1 NC_004116.1 hypothetical protein 784395 1013589 SAG0785 Streptococcus agalactiae 2603V/R hypothetical protein NP_687800.1 783403 R 208435 CDS NP_687801.1 22536950 1013590 784571..785299 1 NC_004116.1 hypothetical protein 785299 1013590 SAG0786 Streptococcus agalactiae 2603V/R hypothetical protein NP_687801.1 784571 D 208435 CDS NP_687802.1 22536951 1013591 785353..786390 1 NC_004116.1 required for the assembly and function of the DNAX complex which is required for the assembly of the beta subunit onto primed DNA; DNA polymerase III subunit delta 786390 holA 1013591 holA Streptococcus agalactiae 2603V/R DNA polymerase III subunit delta NP_687802.1 785353 D 208435 CDS NP_687803.1 22536952 1013592 786470..787078 1 NC_004116.1 identified by match to PFAM protein family HMM PF00081; superoxide dismutase 787078 sodA 1013592 sodA Streptococcus agalactiae 2603V/R superoxide dismutase NP_687803.1 786470 D 208435 CDS NP_687804.1 22536953 1013593 787416..788267 1 NC_004116.1 identified by match to PFAM protein family HMM PF00874; transcriptional antiterminator LicT 788267 1013593 SAG0789 Streptococcus agalactiae 2603V/R transcriptional antiterminator LicT NP_687804.1 787416 D 208435 CDS NP_687805.1 22536954 1013594 788260..790128 1 NC_004116.1 identified by match to PFAM protein family HMM PF00358; PTS system beta-glucosides-specific transporter subunit IIABC 790128 1013594 SAG0790 Streptococcus agalactiae 2603V/R PTS system beta-glucosides-specific transporter subunit IIABC NP_687805.1 788260 D 208435 CDS NP_687806.1 22536955 1013595 790145..791572 1 NC_004116.1 identified by match to PFAM protein family HMM PF00232; 6-phospho-beta-glucosidase 791572 bglA 1013595 bglA Streptococcus agalactiae 2603V/R 6-phospho-beta-glucosidase NP_687806.1 790145 D 208435 CDS NP_687807.1 22536956 1013596 complement(791641..792735) 1 NC_004116.1 hypothetical protein 792735 1013596 SAG0792 Streptococcus agalactiae 2603V/R hypothetical protein NP_687807.1 791641 R 208435 CDS NP_687808.1 22536957 1013597 792902..794044 1 NC_004116.1 identified by match to PFAM protein family HMM PF02595; The product of this gene was detected by Western blot analysis. For details on the method see Tettelin et al. 2002.; glycerate kinase 794044 garK 1013597 garK Streptococcus agalactiae 2603V/R glycerate kinase NP_687808.1 792902 D 208435 CDS NP_687809.1 22536958 1013598 794069..795325 1 NC_004116.1 identified by match to PFAM protein family HMM PF02447; GntP family permease 795325 1013598 SAG0794 Streptococcus agalactiae 2603V/R GntP family permease NP_687809.1 794069 D 208435 CDS NP_687810.1 22536959 1013599 795426..796490 1 NC_004116.1 hypothetical protein 796490 1013599 SAG0795 Streptococcus agalactiae 2603V/R hypothetical protein NP_687810.1 795426 D 208435 CDS NP_687811.1 22536960 1013600 complement(796545..796988) 1 NC_004116.1 identified by match to PFAM protein family HMM PF01047; MarR family transcriptional regulator 796988 1013600 SAG0796 Streptococcus agalactiae 2603V/R MarR family transcriptional regulator NP_687811.1 796545 R 208435 CDS NP_687812.1 22536961 1013601 complement(797069..798097) 1 NC_004116.1 Synthesizes oQ from preQ1 in a single S-adenosylmethionine-requiring step; S-adenosylmethionine--tRNA ribosyltransferase-isomerase 798097 queA 1013601 queA Streptococcus agalactiae 2603V/R S-adenosylmethionine--tRNA ribosyltransferase-isomerase NP_687812.1 797069 R 208435 CDS NP_687813.1 22536962 1013602 798250..798930 1 NC_004116.1 hypothetical protein 798930 1013602 SAG0798 Streptococcus agalactiae 2603V/R hypothetical protein NP_687813.1 798250 D 208435 CDS NP_687814.1 22536963 1013603 799081..799782 1 NC_004116.1 identified by match to PFAM protein family HMM PF01182; glucosamine-6-phosphate isomerase 799782 nagB 1013603 nagB Streptococcus agalactiae 2603V/R glucosamine-6-phosphate isomerase NP_687814.1 799081 D 208435 CDS NP_687815.1 22536964 1013604 complement(799854..800810) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00043; glutathione S-transferase family protein 800810 1013604 SAG0800 Streptococcus agalactiae 2603V/R glutathione S-transferase family protein NP_687815.1 799854 R 208435 CDS NP_687816.1 22536965 1013605 800906..801625 1 NC_004116.1 identified by match to PFAM protein family HMM PF00849; ribosomal small subunit pseudouridine synthase A 801625 1013605 SAG0801 Streptococcus agalactiae 2603V/R ribosomal small subunit pseudouridine synthase A NP_687816.1 800906 D 208435 CDS NP_687817.1 22536966 1013606 complement(801600..801716) 1 NC_004116.1 hypothetical protein 801716 1013606 SAG0802 Streptococcus agalactiae 2603V/R hypothetical protein NP_687817.1 801600 R 208435 CDS NP_687818.1 22536967 1013607 801698..802849 1 NC_004116.1 identified by match to PFAM protein family HMM PF00083; major facilitator family protein 802849 1013607 SAG0803 Streptococcus agalactiae 2603V/R major facilitator family protein NP_687818.1 801698 D 208435 CDS NP_687819.1 22536968 1013608 802901..803848 1 NC_004116.1 similar to OMNI:SP0978; identified by sequence similarity; competence protein CoiA 803848 coiA 1013608 coiA Streptococcus agalactiae 2603V/R competence protein CoiA NP_687819.1 802901 D 208435 CDS NP_687820.1 22536969 1013609 803864..805669 1 NC_004116.1 identified by match to PFAM protein family HMM PF01432; group B oligopeptidase PepB 805669 pepB 1013609 pepB Streptococcus agalactiae 2603V/R group B oligopeptidase PepB NP_687820.1 803864 D 208435 CDS NP_687821.1 22536970 1013610 805864..806490 1 NC_004116.1 identified by match to PFAM protein family HMM PF00702; HAD superfamily hydrolase 806490 1013610 SAG0806 Streptococcus agalactiae 2603V/R HAD superfamily hydrolase NP_687821.1 805864 D 208435 CDS NP_687822.1 22536971 1013611 806564..807271 1 NC_004116.1 identified by match to PFAM protein family HMM PF01596; O-methyltransferase family protein 807271 1013611 SAG0807 Streptococcus agalactiae 2603V/R O-methyltransferase family protein NP_687822.1 806564 D 208435 CDS NP_687823.1 22536972 1013612 807332..808261 1 NC_004116.1 cis/trans isomerase of peptidylprolyl; PPIase; membrane-bound lipoprotein; foldase protein PrsA 808261 prsA 1013612 prsA Streptococcus agalactiae 2603V/R foldase protein PrsA NP_687823.1 807332 D 208435 CDS NP_687824.1 22536973 1013613 808503..808988 1 NC_004116.1 hypothetical protein 808988 1013613 SAG0809 Streptococcus agalactiae 2603V/R hypothetical protein NP_687824.1 808503 D 208435 CDS NP_687825.1 22536974 1013614 809004..811622 1 NC_004116.1 Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; alanyl-tRNA synthetase 811622 alaS 1013614 alaS Streptococcus agalactiae 2603V/R alanyl-tRNA synthetase NP_687825.1 809004 D 208435 CDS NP_687826.1 22536975 1013615 811704..812420 1 NC_004116.1 similar to OMNI:NTL01BH4061; identified by sequence similarity; hypothetical protein 812420 1013615 SAG0811 Streptococcus agalactiae 2603V/R hypothetical protein NP_687826.1 811704 D 208435 CDS NP_687827.1 22536976 1013616 812508..813326 1 NC_004116.1 identified by match to PFAM protein family HMM PF01501; glycosyl transferase family protein 813326 1013616 SAG0812 Streptococcus agalactiae 2603V/R glycosyl transferase family protein NP_687827.1 812508 D 208435 CDS NP_687828.1 22536977 1013617 813470..813715 1 NC_004116.1 hypothetical protein 813715 1013617 SAG0813 Streptococcus agalactiae 2603V/R hypothetical protein NP_687828.1 813470 D 208435 CDS NP_687829.1 22536978 1013618 813754..814041 1 NC_004116.1 hypothetical protein 814041 1013618 SAG0814 Streptococcus agalactiae 2603V/R hypothetical protein NP_687829.1 813754 D 208435 CDS NP_687830.1 22536979 1013619 814086..814301 1 NC_004116.1 identified by match to PFAM protein family HMM PF01381; Cro/CI family transcriptional regulator 814301 1013619 SAG0815 Streptococcus agalactiae 2603V/R Cro/CI family transcriptional regulator NP_687830.1 814086 D 208435 CDS NP_687831.1 22536980 1013620 814301..815062 1 NC_004116.1 similar to OMNI:NTL01SPL1088; identified by sequence similarity; hypothetical protein 815062 1013620 SAG0816 Streptococcus agalactiae 2603V/R hypothetical protein NP_687831.1 814301 D 208435 CDS NP_687832.1 22536981 1013621 complement(815147..815710) 1 NC_004116.1 similar to OMNI:NTL01SPL0446; identified by sequence similarity; hypothetical protein 815710 1013621 SAG0817 Streptococcus agalactiae 2603V/R hypothetical protein NP_687832.1 815147 R 208435 CDS NP_687833.1 22536982 1013622 complement(815951..816910) 1 NC_004116.1 B2 or R2 protein; type 1b enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdE; ribonucleotide-diphosphate reductase subunit beta 816910 nrdF 1013622 nrdF Streptococcus agalactiae 2603V/R ribonucleotide-diphosphate reductase subunit beta NP_687833.1 815951 R 208435 CDS NP_687834.1 22536983 1013623 complement(817113..819272) 1 NC_004116.1 Catalyzes the rate-limiting step in dNTP synthesis; ribonucleotide-diphosphate reductase subunit alpha 819272 nrdE-2 1013623 nrdE-2 Streptococcus agalactiae 2603V/R ribonucleotide-diphosphate reductase subunit alpha NP_687834.1 817113 R 208435 CDS NP_687835.1 22536984 1013624 complement(819350..819574) 1 NC_004116.1 ribonucleoside-diphosphate reductase 2, NrdH-redoxin 819574 nrdH 1013624 nrdH Streptococcus agalactiae 2603V/R ribonucleoside-diphosphate reductase 2, NrdH-redoxin NP_687835.1 819350 R 208435 CDS NP_687836.1 22536985 1013625 819957..820220 1 NC_004116.1 identified by match to PFAM protein family HMM PF00381; phosphocarrier protein HPr 820220 ptsH 1013625 ptsH Streptococcus agalactiae 2603V/R phosphocarrier protein HPr NP_687836.1 819957 D 208435 CDS NP_687837.1 22536986 1013626 820225..821958 1 NC_004116.1 identified by match to PFAM protein family HMM PF00391; phosphoenolpyruvate-protein phosphotransferase 821958 ptsI 1013626 ptsI Streptococcus agalactiae 2603V/R phosphoenolpyruvate-protein phosphotransferase NP_687837.1 820225 D 208435 CDS NP_687838.1 22536987 1013627 822108..823535 1 NC_004116.1 identified by match to PFAM protein family HMM PF00171; glyceraldehyde-3-phosphate dehydrogenase 823535 gapN 1013627 gapN Streptococcus agalactiae 2603V/R glyceraldehyde-3-phosphate dehydrogenase NP_687838.1 822108 D 208435 CDS NP_687839.1 22536988 1013628 823675..824928 1 NC_004116.1 identified by match to PFAM protein family HMM PF01522; polysaccharide deacetylase 824928 1013628 SAG0824 Streptococcus agalactiae 2603V/R polysaccharide deacetylase NP_687839.1 823675 D 208435 CDS NP_687840.1 22536989 1013629 complement(824961..826043) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00270; DEAD/DEAH box helicase 826043 1013629 SAG0825 Streptococcus agalactiae 2603V/R DEAD/DEAH box helicase NP_687840.1 824961 R 208435 CDS NP_687841.1 22536990 1013630 826188..826817 1 NC_004116.1 functions in pyrimidine salvage; pyrimidine ribonucleoside kinase; phosphorylates nucleosides or dinucleosides to make UMP or CMP using ATP or GTP as the donor; uridine kinase 826817 udk 1013630 udk Streptococcus agalactiae 2603V/R uridine kinase NP_687841.1 826188 D 208435 CDS NP_687842.1 22536991 1013631 826904..827401 1 NC_004116.1 hypothetical protein 827401 1013631 SAG0827 Streptococcus agalactiae 2603V/R hypothetical protein NP_687842.1 826904 D 208435 CDS NP_687843.1 22536992 1013632 827401..829065 1 NC_004116.1 catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the tau chain serves as a scaffold to help in the dimerizaton of the alpha,epsilon and theta core complex; the gamma chain seems to interact with the delta and delta' subunits to transfer the beta subunit on the DNA; DNA polymerase III subunits gamma and tau 829065 dnaX 1013632 dnaX Streptococcus agalactiae 2603V/R DNA polymerase III subunits gamma and tau NP_687843.1 827401 D 208435 CDS NP_687844.1 22536993 1013633 829154..829348 1 NC_004116.1 hypothetical protein 829348 1013633 SAG0829 Streptococcus agalactiae 2603V/R hypothetical protein NP_687844.1 829154 D 208435 CDS NP_687845.1 22536994 1013634 complement(829329..830264) 1 NC_004116.1 catalyzes the formation of biotinyl-5'-AMP, also acts as a transcriptional repressor of the biotin operon; biotin--protein ligase 830264 1013634 SAG0830 Streptococcus agalactiae 2603V/R biotin--protein ligase NP_687845.1 829329 R 208435 CDS NP_687846.1 22536995 1013635 830449..831645 1 NC_004116.1 methionine adenosyltransferase; catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase; S-adenosylmethionine synthetase 831645 metK 1013635 metK Streptococcus agalactiae 2603V/R S-adenosylmethionine synthetase NP_687846.1 830449 D 208435 CDS NP_687847.1 22536996 1013636 832166..834427 1 NC_004116.1 identified by Glimmer2; The product of this gene was detected by Western blot analysis. For details on the method see Tettelin et al. 2002.; hypothetical protein 834427 1013636 SAG0832 Streptococcus agalactiae 2603V/R hypothetical protein NP_687847.1 832166 D 208435 CDS NP_687848.1 22536997 1013637 834494..835039 1 NC_004116.1 hypothetical protein 835039 1013637 SAG0833 Streptococcus agalactiae 2603V/R hypothetical protein NP_687848.1 834494 D 208435 CDS NP_687849.1 22536998 1013638 835199..835327 1 NC_004116.1 hypothetical protein 835327 1013638 SAG0834 Streptococcus agalactiae 2603V/R hypothetical protein NP_687849.1 835199 D 208435 CDS NP_687850.1 22536999 1013639 835435..836001 1 NC_004116.1 hypothetical protein 836001 1013639 SAG0835 Streptococcus agalactiae 2603V/R hypothetical protein NP_687850.1 835435 D 208435 CDS NP_687851.1 22537000 1013640 835998..836552 1 NC_004116.1 hypothetical protein 836552 1013640 SAG0836 Streptococcus agalactiae 2603V/R hypothetical protein NP_687851.1 835998 D 208435 CDS NP_687852.1 22537001 1013641 836556..837842 1 NC_004116.1 identified by match to PFAM protein family HMM PF00005; ABC transporter ATP-binding protein 837842 1013641 SAG0837 Streptococcus agalactiae 2603V/R ABC transporter ATP-binding protein NP_687852.1 836556 D 208435 CDS NP_687853.1 22537002 1013642 837797..838498 1 NC_004116.1 hypothetical protein 838498 1013642 SAG0838 Streptococcus agalactiae 2603V/R hypothetical protein NP_687853.1 837797 D 208435 CDS NP_687854.1 22537003 1013643 838582..839262 1 NC_004116.1 identified by match to PFAM protein family HMM PF03070; TenA family transcriptional regulator 839262 1013643 SAG0839 Streptococcus agalactiae 2603V/R TenA family transcriptional regulator NP_687854.1 838582 D 208435 CDS NP_687855.1 22537004 1013644 839264..840061 1 NC_004116.1 catalyzes the formation of 4-amino-2-methyl-5-diphosphomethylpyrimidine; phosphomethylpyrimidine kinase 840061 thiD 1013644 thiD Streptococcus agalactiae 2603V/R phosphomethylpyrimidine kinase NP_687855.1 839264 D 208435 CDS NP_687856.1 22537005 1013645 840063..840833 1 NC_004116.1 catalyzes the formation of 4-methyl-5-(2-phosphoethyl)-thiazole and ADP from 4-methyl-5-(2-hydroxyethyl)-thiazole and ATP; hydroxyethylthiazole kinase 840833 thiM 1013645 thiM Streptococcus agalactiae 2603V/R hydroxyethylthiazole kinase NP_687856.1 840063 D 208435 CDS NP_687857.1 22537006 1013646 840847..841518 1 NC_004116.1 Condenses 4-methyl-5-(beta-hydroxyethyl)-thiazole monophosphate and 4-amino-5-hydroxymethyl pyrimidine pyrophosphate to form thiamine monophosphate; thiamine-phosphate pyrophosphorylase 841518 thiE 1013646 thiE Streptococcus agalactiae 2603V/R thiamine-phosphate pyrophosphorylase NP_687857.1 840847 D 208435 CDS NP_687858.1 22537007 1013647 841645..842904 1 NC_004116.1 adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active; UDP-N-acetylglucosamine 1-carboxyvinyltransferase 842904 murA-1 1013647 murA-1 Streptococcus agalactiae 2603V/R UDP-N-acetylglucosamine 1-carboxyvinyltransferase NP_687858.1 841645 D 208435 CDS NP_687859.1 22537008 1013648 843006..843560 1 NC_004116.1 identified by match to PFAM protein family HMM PF00583; acetyltransferase 843560 1013648 SAG0844 Streptococcus agalactiae 2603V/R acetyltransferase NP_687859.1 843006 D 208435 CDS NP_687860.1 22537009 1013649 843553..844836 1 NC_004116.1 identified by match to PFAM protein family HMM PF00571; hypothetical protein 844836 1013649 SAG0845 Streptococcus agalactiae 2603V/R hypothetical protein NP_687860.1 843553 D 208435 CDS NP_687861.1 22537010 1013650 844859..845719 1 NC_004116.1 catalyzes the removal of N-terminal amino acids from peptides and arylamides; methionine aminopeptidase 845719 map 1013650 map Streptococcus agalactiae 2603V/R methionine aminopeptidase NP_687861.1 844859 D 208435 CDS NP_687862.1 22537011 1013651 845721..846641 1 NC_004116.1 identified by match to TIGR protein family HMM TIGR00765; ribonuclease BN 846641 1013651 SAG0847 Streptococcus agalactiae 2603V/R ribonuclease BN NP_687862.1 845721 D 208435 CDS NP_687863.1 22537012 1013652 complement(846658..847113) 1 NC_004116.1 similar to GB:X73124 SP:P39602 PID:413958 GB:AL009126; identified by sequence similarity; GtrA family protein 847113 1013652 SAG0848 Streptococcus agalactiae 2603V/R GtrA family protein NP_687863.1 846658 R 208435 CDS NP_687864.1 22537013 1013653 847295..847804 1 NC_004116.1 hypothetical protein 847804 1013653 SAG0849 Streptococcus agalactiae 2603V/R hypothetical protein NP_687864.1 847295 D 208435 CDS NP_687865.1 22537014 1013654 847944..849902 1 NC_004116.1 this protein catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction; essential for DNA replication and repair of damaged DNA; similar to ligase LigB; NAD-dependent DNA ligase LigA 849902 ligA 1013654 ligA Streptococcus agalactiae 2603V/R NAD-dependent DNA ligase LigA NP_687865.1 847944 D 208435 CDS NP_687866.1 22537015 1013655 849914..850933 1 NC_004116.1 similar to YegS from E. coli; lipid kinase 850933 1013655 SAG0851 Streptococcus agalactiae 2603V/R lipid kinase NP_687866.1 849914 D 208435 CDS NP_687867.1 22537016 1013656 850937..853237 1 NC_004116.1 identified by match to PFAM protein family HMM PF00128; pullulanase 853237 1013656 SAG0852 Streptococcus agalactiae 2603V/R pullulanase NP_687867.1 850937 D 208435 CDS NP_687868.1 22537017 1013657 853443..855311 1 NC_004116.1 catalyzes the transfer of a segment of a 1,4-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain; glycogen branching protein 855311 glgB 1013657 glgB Streptococcus agalactiae 2603V/R glycogen branching protein NP_687868.1 853443 D 208435 CDS NP_687869.1 22537018 1013658 855353..856492 1 NC_004116.1 catalyzes the formation of ADP-glucose and diphosphate from ATP and alpha-D-glucose 1-phosphate; glucose-1-phosphate adenylyltransferase 856492 glgC 1013658 glgC Streptococcus agalactiae 2603V/R glucose-1-phosphate adenylyltransferase NP_687869.1 855353 D 208435 CDS NP_687870.1 22537019 1013660 857611..859041 1 NC_004116.1 catalyzes the formation of alpha-1,4-glucan chains from ADP-glucose; glycogen synthase 859041 glgA 1013660 glgA Streptococcus agalactiae 2603V/R glycogen synthase NP_687870.1 857611 D 208435 CDS NP_687871.1 22537020 1013661 859373..859573 1 NC_004116.1 produces ATP from ADP in the presence of a proton gradient across the membrane; subunit C is part of the membrane proton channel F0; ATP synthase F0F1 subunit C 859573 atpE 1013661 atpE Streptococcus agalactiae 2603V/R ATP synthase F0F1 subunit C NP_687871.1 859373 D 208435 CDS NP_687872.1 22537021 1013662 859606..860322 1 NC_004116.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0; ATP synthase F0F1 subunit A 860322 atpB 1013662 atpB Streptococcus agalactiae 2603V/R ATP synthase F0F1 subunit A NP_687872.1 859606 D 208435 CDS NP_687873.1 22537022 1013663 860340..860837 1 NC_004116.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit B is part of the membrane proton channel.; ATP synthase F0F1 subunit B 860837 atpF 1013663 atpF Streptococcus agalactiae 2603V/R ATP synthase F0F1 subunit B NP_687873.1 860340 D 208435 CDS NP_687874.1 22537023 1013664 860837..861373 1 NC_004116.1 Produces ATP from ADP in the presence of a proton gradient across the membrane; the delta subunit is part of the catalytic core of the ATP synthase complex; ATP synthase F0F1 subunit delta 861373 atpH 1013664 atpH Streptococcus agalactiae 2603V/R ATP synthase F0F1 subunit delta NP_687874.1 860837 D 208435 CDS NP_687875.1 22537024 1013665 861389..862894 1 NC_004116.1 produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit; ATP synthase F0F1 subunit alpha 862894 atpA 1013665 atpA Streptococcus agalactiae 2603V/R ATP synthase F0F1 subunit alpha NP_687875.1 861389 D 208435 CDS NP_687876.1 22537025 1013666 862910..863791 1 NC_004116.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is a regulatory subunit; ATP synthase F0F1 subunit gamma 863791 atpG 1013666 atpG Streptococcus agalactiae 2603V/R ATP synthase F0F1 subunit gamma NP_687876.1 862910 D 208435 CDS NP_687877.1 22537026 1013667 863865..865271 1 NC_004116.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit; ATP synthase F0F1 subunit beta 865271 atpD 1013667 atpD Streptococcus agalactiae 2603V/R ATP synthase F0F1 subunit beta NP_687877.1 863865 D 208435 CDS NP_687878.1 22537027 1013668 865284..865697 1 NC_004116.1 part of catalytic core of ATP synthase; alpha(3)beta(3)gamma(1)delta(1)epsilon(1); involved in producing ATP from ADP in the presence of the proton motive force across the membrane; ATP synthase F0F1 subunit epsilon 865697 atpC 1013668 atpC Streptococcus agalactiae 2603V/R ATP synthase F0F1 subunit epsilon NP_687878.1 865284 D 208435 CDS NP_687879.1 22537028 1013669 865762..865992 1 NC_004116.1 hypothetical protein 865992 1013669 SAG0865 Streptococcus agalactiae 2603V/R hypothetical protein NP_687879.1 865762 D 208435 CDS NP_687880.1 22537029 1013670 866055..867326 1 NC_004116.1 adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active; UDP-N-acetylglucosamine 1-carboxyvinyltransferase 867326 murA-2 1013670 murA-2 Streptococcus agalactiae 2603V/R UDP-N-acetylglucosamine 1-carboxyvinyltransferase NP_687880.1 866055 D 208435 CDS NP_687881.1 22537030 1013671 867328..867519 1 NC_004116.1 hypothetical protein 867519 1013671 SAG0867 Streptococcus agalactiae 2603V/R hypothetical protein NP_687881.1 867328 D 208435 CDS NP_687882.1 22537031 1013672 867594..868451 1 NC_004116.1 identified by match to PFAM protein family HMM PF01223; DNA-entry nuclease 868451 endA 1013672 endA Streptococcus agalactiae 2603V/R DNA-entry nuclease NP_687882.1 867594 D 208435 CDS NP_687883.1 22537032 1013673 868743..869783 1 NC_004116.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily; phenylalanyl-tRNA synthetase subunit alpha 869783 pheS 1013673 pheS Streptococcus agalactiae 2603V/R phenylalanyl-tRNA synthetase subunit alpha NP_687883.1 868743 D 208435 CDS NP_687884.1 22537033 1013674 869866..870387 1 NC_004116.1 identified by match to PFAM protein family HMM PF00583; acetyltransferase 870387 1013674 SAG0870 Streptococcus agalactiae 2603V/R acetyltransferase NP_687884.1 869866 D 208435 CDS NP_687885.1 22537034 1013675 870441..872846 1 NC_004116.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily; phenylalanyl-tRNA synthetase subunit beta 872846 pheT 1013675 pheT Streptococcus agalactiae 2603V/R phenylalanyl-tRNA synthetase subunit beta NP_687885.1 870441 D 208435 CDS NP_687886.1 22537035 1013676 complement(872915..873817) 1 NC_004116.1 hypothetical protein 873817 1013676 SAG0872 Streptococcus agalactiae 2603V/R hypothetical protein NP_687886.1 872915 R 208435 CDS NP_687887.1 22537036 1013677 873995..877228 1 NC_004116.1 similar to GP:2909715; identified by sequence similarity; RexAB system found in Gram positive bacteria appears to fulfill the biological roles of RecBCD found in Gram negative bacteria.; exonuclease RexB 877228 rexB 1013677 rexB Streptococcus agalactiae 2603V/R exonuclease RexB NP_687887.1 873995 D 208435 CDS NP_687888.1 22537037 1013678 877218..880841 1 NC_004116.1 identified by match to PFAM protein family HMM PF00580; RexAB system found in Gram positive bacteria appears to fulfill the biological roles of RecBCD found in Gram negative bacteria.; exonuclease RexA 880841 rexA 1013678 rexA Streptococcus agalactiae 2603V/R exonuclease RexA NP_687888.1 877218 D 208435 CDS NP_687889.1 22537038 1013679 880854..881771 1 NC_004116.1 identified by match to PFAM protein family HMM PF01544; magnesium transporter CorA family protein 881771 1013679 SAG0875 Streptococcus agalactiae 2603V/R magnesium transporter CorA family protein NP_687889.1 880854 D 208435 CDS NP_687890.1 22537039 1013680 complement(881804..883180) 1 NC_004116.1 in Escherichia coli this protein is involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2-thiouridine, which is found in the wobble position of some tRNAs and affects ribosomal frameshifting; shows potassium-dependent dimerization and GTP hydrolysis; also involved in regulation of glutamate-dependent acid resistance and activation of gadE; tRNA modification GTPase TrmE 883180 trmE 1013680 trmE Streptococcus agalactiae 2603V/R tRNA modification GTPase TrmE NP_687890.1 881804 R 208435 CDS NP_687891.1 22537040 1013681 883308..885218 1 NC_004116.1 identified by match to PFAM protein family HMM PF00005; ABC transporter ATP-binding protein 885218 1013681 SAG0877 Streptococcus agalactiae 2603V/R ABC transporter ATP-binding protein NP_687891.1 883308 D 208435 CDS NP_687892.1 22537041 1013682 885368..886336 1 NC_004116.1 identified by match to PFAM protein family HMM PF00676; acetoin dehydrogenase, thymine PPi dependent, E1 component subunit alpha 886336 1013682 SAG0878 Streptococcus agalactiae 2603V/R acetoin dehydrogenase, thymine PPi dependent, E1 component subunit alpha NP_687892.1 885368 D 208435 CDS NP_687893.1 22537042 1013683 886411..887409 1 NC_004116.1 identified by match to PFAM protein family HMM PF02779; acetoin dehydrogenase, thymine PPi dependent, E1 component subunit beta 887409 1013683 SAG0879 Streptococcus agalactiae 2603V/R acetoin dehydrogenase, thymine PPi dependent, E1 component subunit beta NP_687893.1 886411 D 208435 CDS NP_687894.1 22537043 1013684 887536..888924 1 NC_004116.1 Catalyzes the transfer of acetyl from acetyldihydrolipoamide to coenzyme A to form acetyl CoA; branched-chain alpha-keto acid dehydrogenase subunit E2 888924 1013684 SAG0880 Streptococcus agalactiae 2603V/R branched-chain alpha-keto acid dehydrogenase subunit E2 NP_687894.1 887536 D 208435 CDS NP_687895.1 22537044 1013685 888984..890741 1 NC_004116.1 identified by match to PFAM protein family HMM PF00070; acetoin dehydrogenase, thymine PPi dependent, E3 component, dihydrolipoamide dehydrogenase 890741 1013685 SAG0881 Streptococcus agalactiae 2603V/R acetoin dehydrogenase, thymine PPi dependent, E3 component, dihydrolipoamide dehydrogenase NP_687895.1 888984 D 208435 CDS NP_687896.1 22537045 1013686 890839..891828 1 NC_004116.1 identified by match to PFAM protein family HMM PF02539; lipoate-protein ligase A 891828 lplA-1 1013686 lplA-1 Streptococcus agalactiae 2603V/R lipoate-protein ligase A NP_687896.1 890839 D 208435 CDS NP_687897.1 22537046 1013687 complement(891936..892721) 1 NC_004116.1 similar to OMNI:NTL01LL1120; identified by sequence similarity; cobyric acid synthase 892721 1013687 SAG0883 Streptococcus agalactiae 2603V/R cobyric acid synthase NP_687897.1 891936 R 208435 CDS NP_687898.1 22537047 1013688 complement(892721..894064) 1 NC_004116.1 mur ligase family protein 894064 1013688 SAG0884 Streptococcus agalactiae 2603V/R mur ligase family protein NP_687898.1 892721 R 208435 CDS NP_687899.1 22537048 1013689 894204..895055 1 NC_004116.1 hypothetical protein 895055 1013689 SAG0885 Streptococcus agalactiae 2603V/R hypothetical protein NP_687899.1 894204 D 208435 CDS NP_687900.1 22537049 1013690 895058..896017 1 NC_004116.1 The product of this gene was detected by Western blot analysis. For details on the method see Tettelin et al. 2002.; hypothetical protein 896017 1013690 SAG0886 Streptococcus agalactiae 2603V/R hypothetical protein NP_687900.1 895058 D 208435 CDS NP_687901.1 22537050 1013691 896071..897423 1 NC_004116.1 catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; phosphoglucosamine mutase 897423 glmM 1013691 glmM Streptococcus agalactiae 2603V/R phosphoglucosamine mutase NP_687901.1 896071 D 208435 CDS NP_687902.1 22537051 1013692 897546..897917 1 NC_004116.1 hypothetical protein 897917 1013692 SAG0888 Streptococcus agalactiae 2603V/R hypothetical protein NP_687902.1 897546 D 208435 CDS NP_687903.1 22537052 1013693 897942..898322 1 NC_004116.1 hypothetical protein 898322 1013693 SAG0889 Streptococcus agalactiae 2603V/R hypothetical protein NP_687903.1 897942 D 208435 CDS NP_687904.1 22537053 1013694 898414..899544 1 NC_004116.1 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III; coproporphyrinogen III oxidase 899544 1013694 SAG0890 Streptococcus agalactiae 2603V/R coproporphyrinogen III oxidase NP_687904.1 898414 D 208435 CDS NP_687905.1 22537054 1013695 899548..900285 1 NC_004116.1 hypothetical protein 900285 1013695 SAG0891 Streptococcus agalactiae 2603V/R hypothetical protein NP_687905.1 899548 D 208435 CDS NP_687906.1 22537055 1013696 900286..901056 1 NC_004116.1 identified by match to PFAM protein family HMM PF00702; HAD superfamily hydrolase 901056 1013696 SAG0892 Streptococcus agalactiae 2603V/R HAD superfamily hydrolase NP_687906.1 900286 D 208435 CDS NP_687907.1 22537056 1013697 901046..901702 1 NC_004116.1 hypothetical protein 901702 1013697 SAG0893 Streptococcus agalactiae 2603V/R hypothetical protein NP_687907.1 901046 D 208435 CDS NP_687908.1 22537057 1013698 902090..906202 1 NC_004116.1 similar to OMNI:NTL01SPL0811; identified by sequence similarity; The product of this gene was detected by Western blot analysis. For details on the method see Tettelin et al. 2002.; hypothetical protein 906202 1013698 SAG0894 Streptococcus agalactiae 2603V/R hypothetical protein NP_687908.1 902090 D 208435 CDS NP_687909.1 22537058 1013699 906204..907073 1 NC_004116.1 lipoyl-binding domain-containing protein 907073 1013699 SAG0895 Streptococcus agalactiae 2603V/R lipoyl-binding domain-containing protein NP_687909.1 906204 D 208435 CDS NP_687910.1 22537059 1013700 907085..907411 1 NC_004116.1 similar to OMNI:NTL01SPL0813; identified by sequence similarity; oxidoreductase 907411 1013700 SAG0896 Streptococcus agalactiae 2603V/R oxidoreductase NP_687910.1 907085 D 208435 CDS NP_687911.1 22537060 1013701 907398..908063 1 NC_004116.1 hypothetical protein 908063 1013701 SAG0897 Streptococcus agalactiae 2603V/R hypothetical protein NP_687911.1 907398 D 208435 CDS NP_687912.1 22537061 1013702 908175..908426 1 NC_004116.1 hypothetical protein 908426 1013702 SAG0898 Streptococcus agalactiae 2603V/R hypothetical protein NP_687912.1 908175 D 208435 CDS NP_687913.1 22537062 1013703 908439..908612 1 NC_004116.1 hypothetical protein 908612 1013703 SAG0899 Streptococcus agalactiae 2603V/R hypothetical protein NP_687913.1 908439 D 208435 CDS NP_687914.1 22537063 1013704 908847..909017 1 NC_004116.1 hypothetical protein 909017 1013704 SAG0900 Streptococcus agalactiae 2603V/R hypothetical protein NP_687914.1 908847 D 208435 CDS NP_687915.1 22537064 1013705 909099..909482 1 NC_004116.1 hypothetical protein 909482 1013705 SAG0901 Streptococcus agalactiae 2603V/R hypothetical protein NP_687915.1 909099 D 208435 CDS NP_687916.1 22537065 1013706 909460..909597 1 NC_004116.1 hypothetical protein 909597 1013706 SAG0902 Streptococcus agalactiae 2603V/R hypothetical protein NP_687916.1 909460 D 208435 CDS NP_687917.1 22537066 1013707 909601..909735 1 NC_004116.1 hypothetical protein 909735 1013707 SAG0903 Streptococcus agalactiae 2603V/R hypothetical protein NP_687917.1 909601 D 208435 CDS NP_687918.1 22537067 1013708 910104..910274 1 NC_004116.1 hypothetical protein 910274 1013708 SAG0904 Streptococcus agalactiae 2603V/R hypothetical protein NP_687918.1 910104 D 208435 CDS NP_687919.1 22537068 1013709 910407..910823 1 NC_004116.1 catalyzes the formation of nucleoside triphosphate from ATP and nucleoside diphosphate; nucleoside diphosphate kinase 910823 ndk 1013709 ndk Streptococcus agalactiae 2603V/R nucleoside diphosphate kinase NP_687919.1 910407 D 208435 CDS NP_687920.1 22537069 1013710 910959..912791 1 NC_004116.1 binds to the ribosome on the universally-conserved alpha-sarcin loop; GTP-binding protein LepA 912791 lepA 1013710 lepA Streptococcus agalactiae 2603V/R GTP-binding protein LepA NP_687920.1 910959 D 208435 CDS NP_687921.1 22537070 1013711 913038..915671 1 NC_004116.1 identified by match to PFAM protein family HMM PF00560; The product of this gene was detected by Western blot analysis. For details on the method see Tettelin et al. 2002.; hypothetical protein 915671 1013711 SAG0907 Streptococcus agalactiae 2603V/R hypothetical protein NP_687921.1 913038 D 208435 CDS NP_687922.1 22537071 1013712 915819..916430 1 NC_004116.1 identified by match to PFAM protein family HMM PF01966; HD domain-containing protein 916430 1013712 SAG0908 Streptococcus agalactiae 2603V/R HD domain-containing protein NP_687922.1 915819 D 208435 CDS NP_687923.1 22537072 1013713 916439..916903 1 NC_004116.1 identified by match to PFAM protein family HMM PF00583; acetyltransferase 916903 1013713 SAG0909 Streptococcus agalactiae 2603V/R acetyltransferase NP_687923.1 916439 D 208435 CDS NP_687924.1 22537073 1013714 916903..917337 1 NC_004116.1 this stereospecific enzymes reduces the R isomer of methionine sulfoxide while MsrA reduces the S form; provides protection against oxidative stress; methionine sulfoxide reductase B 917337 1013714 SAG0910 Streptococcus agalactiae 2603V/R methionine sulfoxide reductase B NP_687924.1 916903 D 208435 CDS NP_687925.1 22537074 1013715 917489..920281 1 NC_004116.1 identified by match to PFAM protein family HMM PF00122; cation transporter E1-E2 family ATPase 920281 1013715 SAG0911 Streptococcus agalactiae 2603V/R cation transporter E1-E2 family ATPase NP_687925.1 917489 D 208435 CDS NP_687926.1 22537075 1013716 920281..921384 1 NC_004116.1 hypothetical protein 921384 1013716 SAG0912 Streptococcus agalactiae 2603V/R hypothetical protein NP_687926.1 920281 D 208435 CDS NP_687927.1 22537076 1013717 complement(921505..922143) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00132; chloramphenicol acetyltransferase 922143 cat 1013717 cat Streptococcus agalactiae 2603V/R chloramphenicol acetyltransferase NP_687927.1 921505 R 208435 CDS NP_687928.1 22537077 1013718 922854..923465 1 NC_004116.1 hypothetical protein 923465 1013718 SAG0914 Streptococcus agalactiae 2603V/R hypothetical protein NP_687928.1 922854 D 208435 CDS NP_687929.1 22537078 1013719 complement(923639..924856) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00589; Tn916, transposase 924856 1013719 SAG0915 Streptococcus agalactiae 2603V/R Tn916, transposase NP_687929.1 923639 R 208435 CDS NP_687930.1 22537079 1013720 complement(924938..925141) 1 NC_004116.1 similar to SP:P27452 GB:S56948 GB:X61025 PID:47462; identified by sequence similarity; Tn916, excisionase 925141 1013720 SAG0916 Streptococcus agalactiae 2603V/R Tn916, excisionase NP_687930.1 924938 R 208435 CDS NP_687931.1 22537080 1013721 925125..925376 1 NC_004116.1 Tn916 hypothetical protein 925376 1013721 SAG0917 Streptococcus agalactiae 2603V/R Tn916 hypothetical protein NP_687931.1 925125 D 208435 CDS NP_687932.1 22537081 1013722 complement(925602..925832) 1 NC_004116.1 Tn916 hypothetical protein 925832 1013722 SAG0918 Streptococcus agalactiae 2603V/R Tn916 hypothetical protein NP_687932.1 925602 R 208435 CDS NP_687933.1 22537082 1013723 complement(925829..926302) 1 NC_004116.1 Tn916 hypothetical protein 926302 1013723 SAG0919 Streptococcus agalactiae 2603V/R Tn916 hypothetical protein NP_687933.1 925829 R 208435 CDS NP_687934.1 22537083 1013724 complement(926480..926551) 1 NC_004116.1 Tn916 hypothetical protein 926551 1013724 SAG0920 Streptococcus agalactiae 2603V/R Tn916 hypothetical protein NP_687934.1 926480 R 208435 CDS NP_687935.1 22537084 1013725 926756..927109 1 NC_004116.1 identified by match to PFAM protein family HMM PF01381; Tn916, transcriptional regulator 927109 1013725 SAG0921 Streptococcus agalactiae 2603V/R Tn916, transcriptional regulator NP_687935.1 926756 D 208435 CDS NP_687936.1 22537085 1013726 complement(927169..927354) 1 NC_004116.1 Tn916 hypothetical protein 927354 1013726 SAG0922 Streptococcus agalactiae 2603V/R Tn916 hypothetical protein NP_687936.1 927169 R 208435 CDS NP_687937.1 22537086 1013727 complement(927455..929374) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00009; tetracycline resistance protein 929374 tetM 1013727 tetM Streptococcus agalactiae 2603V/R tetracycline resistance protein NP_687937.1 927455 R 208435 CDS NP_687938.1 22537087 1013728 complement(929390..929476) 1 NC_004116.1 regulates the transcription of tet(M) by attenuation; tetracycline resistance determinant leader peptide 929476 1013728 SAG0924 Streptococcus agalactiae 2603V/R tetracycline resistance determinant leader peptide NP_687938.1 929390 R 208435 CDS NP_687939.1 22537088 1013729 complement(929751..930683) 1 NC_004116.1 Tn916 hypothetical protein 930683 1013729 SAG0925 Streptococcus agalactiae 2603V/R Tn916 hypothetical protein NP_687939.1 929751 R 208435 CDS NP_687940.1 22537089 1013730 complement(930680..931681) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00877; Tn916, NLP/P60 family protein 931681 1013730 SAG0926 Streptococcus agalactiae 2603V/R Tn916, NLP/P60 family protein NP_687940.1 930680 R 208435 CDS NP_687941.1 22537090 1013731 complement(931678..933855) 1 NC_004116.1 hypothetical protein 933855 1013731 SAG0927 Streptococcus agalactiae 2603V/R hypothetical protein NP_687941.1 931678 R 208435 CDS NP_687942.1 22537091 1013733 complement(936288..936794) 1 NC_004116.1 Tn916 hypothetical protein 936794 1013733 SAG0929 Streptococcus agalactiae 2603V/R Tn916 hypothetical protein NP_687942.1 936288 R 208435 CDS NP_687943.1 22537092 1013734 complement(936769..937266) 1 NC_004116.1 Tn916 hypothetical protein 937266 1013734 SAG0930 Streptococcus agalactiae 2603V/R Tn916 hypothetical protein NP_687943.1 936769 R 208435 CDS NP_687944.1 22537093 1013735 complement(937383..937604) 1 NC_004116.1 Tn916 hypothetical protein 937604 1013735 SAG0931 Streptococcus agalactiae 2603V/R Tn916 hypothetical protein NP_687944.1 937383 R 208435 CDS NP_687945.1 22537094 1013736 complement(937647..938852) 1 NC_004116.1 identified by match to PFAM protein family HMM PF01381; Tn916, transcriptional regulator 938852 1013736 SAG0932 Streptococcus agalactiae 2603V/R Tn916, transcriptional regulator NP_687945.1 937647 R 208435 CDS NP_687946.1 22537095 1013737 complement(939030..940415) 1 NC_004116.1 identified by match to PFAM protein family HMM PF01580; DNA translocase FtsK 940415 1013737 SAG0933 Streptococcus agalactiae 2603V/R DNA translocase FtsK NP_687946.1 939030 R 208435 CDS NP_687947.1 22537096 1013738 complement(940444..940830) 1 NC_004116.1 Tn916 hypothetical protein 940830 1013738 SAG0934 Streptococcus agalactiae 2603V/R Tn916 hypothetical protein NP_687947.1 940444 R 208435 CDS NP_687948.1 22537097 1013739 complement(940846..941160) 1 NC_004116.1 Tn916 hypothetical protein 941160 1013739 SAG0935 Streptococcus agalactiae 2603V/R Tn916 hypothetical protein NP_687948.1 940846 R 208435 CDS NP_687949.1 22537098 1013740 complement(941183..941302) 1 NC_004116.1 Tn916 hypothetical protein 941302 1013740 SAG0936 Streptococcus agalactiae 2603V/R Tn916 hypothetical protein NP_687949.1 941183 R 208435 CDS NP_687950.1 22537099 1013742 complement(943034..943402) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00392; GntR family transcriptional regulator 943402 1013742 SAG0938 Streptococcus agalactiae 2603V/R GntR family transcriptional regulator NP_687950.1 943034 R 208435 CDS NP_687951.1 22537100 1013743 943547..946651 1 NC_004116.1 Catalyzes DNA-template-directed extension of the 3'-end of a DNA strand by one nucleotide at a time. Proposed to be responsible for the synthesis of the lagging strand. In the low GC gram positive bacteria this enzyme is less processive and more error prone than its counterpart in other bacteria.; DNA polymerase III DnaE 946651 dnaE 1013743 dnaE Streptococcus agalactiae 2603V/R DNA polymerase III DnaE NP_687951.1 943547 D 208435 CDS NP_687952.1 22537101 1013744 946732..947754 1 NC_004116.1 catalyzes the formation of D-fructose 1,6-bisphosphate from D-fructose 6-phosphate in glycolysis; 6-phosphofructokinase 947754 pfkA 1013744 pfkA Streptococcus agalactiae 2603V/R 6-phosphofructokinase NP_687952.1 946732 D 208435 CDS NP_687953.1 22537102 1013745 947803..949305 1 NC_004116.1 catalyzes the formation of phosphoenolpyruvate from pyruvate; pyruvate kinase 949305 pyk 1013745 pyk Streptococcus agalactiae 2603V/R pyruvate kinase NP_687953.1 947803 D 208435 CDS NP_687954.1 22537103 1013746 949476..950033 1 NC_004116.1 identified by match to PFAM protein family HMM PF00461; signal peptidase I 950033 1013746 SAG0942 Streptococcus agalactiae 2603V/R signal peptidase I NP_687954.1 949476 D 208435 CDS NP_687955.1 22537104 1013747 complement(950047..950190) 1 NC_004116.1 hypothetical protein 950190 1013747 SAG0943 Streptococcus agalactiae 2603V/R hypothetical protein NP_687955.1 950047 R 208435 CDS NP_687956.1 22537105 1013748 950302..952116 1 NC_004116.1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source; glucosamine--fructose-6-phosphate aminotransferase 952116 glmS 1013748 glmS Streptococcus agalactiae 2603V/R glucosamine--fructose-6-phosphate aminotransferase NP_687956.1 950302 D 208435 CDS NP_687957.1 22537106 1013749 952293..953426 1 NC_004116.1 identified by match to PFAM protein family HMM PF01609; IS1548 transposase 953426 1013749 SAG0945 Streptococcus agalactiae 2603V/R IS1548 transposase NP_687957.1 952293 D 208435 CDS NP_687958.1 22537107 1013750 953605..953934 1 NC_004116.1 identified by match to TIGR protein family HMM TIGR00686; phnA protein 953934 phnA 1013750 phnA Streptococcus agalactiae 2603V/R phnA protein NP_687958.1 953605 D 208435 CDS NP_687959.1 22537108 1013751 954069..954710 1 NC_004116.1 identified by match to PFAM protein family HMM PF00528; amino acid ABC transporter permease 954710 1013751 SAG0947 Streptococcus agalactiae 2603V/R amino acid ABC transporter permease NP_687959.1 954069 D 208435 CDS NP_687960.1 22537109 1013752 954720..955349 1 NC_004116.1 identified by match to PFAM protein family HMM PF00005; amino acid ABC transporter ATP-binding protein 955349 1013752 SAG0948 Streptococcus agalactiae 2603V/R amino acid ABC transporter ATP-binding protein NP_687960.1 954720 D 208435 CDS NP_687961.1 22537110 1013753 955366..956196 1 NC_004116.1 identified by match to PFAM protein family HMM PF00497; amino acid ABC transporter amino acid-binding protein 956196 1013753 SAG0949 Streptococcus agalactiae 2603V/R amino acid ABC transporter amino acid-binding protein NP_687961.1 955366 D 208435 CDS NP_687962.2 161485614 1013754 complement(956280..956513) 1 NC_004116.1 binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase; 30S ribosomal protein S20 956513 rpsT 1013754 rpsT Streptococcus agalactiae 2603V/R 30S ribosomal protein S20 NP_687962.2 956280 R 208435 CDS NP_687963.1 22537112 1013755 complement(956582..957502) 1 NC_004116.1 catalyzes the formation of (R)-4'-phosphopantothenate in coenzyme A biosynthesis; pantothenate kinase 957502 coaA 1013755 coaA Streptococcus agalactiae 2603V/R pantothenate kinase NP_687963.1 956582 R 208435 CDS NP_687964.1 22537113 1013756 957608..958198 1 NC_004116.1 hypothetical protein 958198 1013756 SAG0952 Streptococcus agalactiae 2603V/R hypothetical protein NP_687964.1 957608 D 208435 CDS NP_687965.1 22537114 1013757 958524..958913 1 NC_004116.1 Reclaims exogenous and endogenous cytidine and 2'-deoxycytidine molecules for UMP synthesis; cytidine deaminase 958913 cdd 1013757 cdd Streptococcus agalactiae 2603V/R cytidine deaminase NP_687965.1 958524 D 208435 CDS NP_687966.1 22537115 1013758 958978..960027 1 NC_004116.1 identified by match to PFAM protein family HMM PF02608; The product of this gene was detected by Western blot analysis. For details on the method see Tettelin et al. 2002.; hypothetical protein 960027 1013758 SAG0954 Streptococcus agalactiae 2603V/R hypothetical protein NP_687966.1 958978 D 208435 CDS NP_687967.1 22537116 1013759 960172..961707 1 NC_004116.1 identified by match to PFAM protein family HMM PF00005; sugar ABC transporter ATP-binding protein 961707 1013759 SAG0955 Streptococcus agalactiae 2603V/R sugar ABC transporter ATP-binding protein NP_687967.1 960172 D 208435 CDS NP_687968.1 22537117 1013760 961700..962761 1 NC_004116.1 sugar ABC transporter permease 962761 1013760 SAG0956 Streptococcus agalactiae 2603V/R sugar ABC transporter permease NP_687968.1 961700 D 208435 CDS NP_687969.1 22537118 1013761 962763..963719 1 NC_004116.1 sugar ABC transporter permease 963719 1013761 SAG0957 Streptococcus agalactiae 2603V/R sugar ABC transporter permease NP_687969.1 962763 D 208435 CDS NP_687970.1 22537119 1013762 963924..965294 1 NC_004116.1 identified by match to PFAM protein family HMM PF00070; NADH oxidase 965294 nox-2 1013762 nox-2 Streptococcus agalactiae 2603V/R NADH oxidase NP_687970.1 963924 D 208435 CDS NP_687971.1 22537120 1013763 complement(965415..966404) 1 NC_004116.1 Converts (S)-lactate and NAD(+) to pyruvate and NADH; L-lactate dehydrogenase 966404 ldh 1013763 ldh Streptococcus agalactiae 2603V/R L-lactate dehydrogenase NP_687971.1 965415 R 208435 CDS NP_687972.1 22537121 1013764 966643..969102 1 NC_004116.1 negatively supercoils closed circular double-stranded DNA; DNA gyrase subunit A 969102 gyrA 1013764 gyrA Streptococcus agalactiae 2603V/R DNA gyrase subunit A NP_687972.1 966643 D 208435 CDS NP_687973.1 22537122 1013765 969109..969852 1 NC_004116.1 identified by match to TIGR protein family HMM TIGR01076; sortase SrtA 969852 srtA 1013765 srtA Streptococcus agalactiae 2603V/R sortase SrtA NP_687973.1 969109 D 208435 CDS NP_687974.1 22537123 1013766 969868..970281 1 NC_004116.1 identified by match to PFAM protein family HMM PF00903; glyoxylase 970281 1013766 SAG0962 Streptococcus agalactiae 2603V/R glyoxylase NP_687974.1 969868 D 208435 CDS NP_687975.1 22537124 1013767 970434..971396 1 NC_004116.1 hypothetical protein 971396 1013767 SAG0963 Streptococcus agalactiae 2603V/R hypothetical protein NP_687975.1 970434 D 208435 CDS NP_687976.1 22537125 1013768 complement(971459..972586) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00999; Na+/H+ exchanger family protein 972586 1013768 SAG0964 Streptococcus agalactiae 2603V/R Na+/H+ exchanger family protein NP_687976.1 971459 R 208435 CDS NP_687977.1 22537126 1013769 972846..973229 1 NC_004116.1 similar to OMNI:SP0537; identified by sequence similarity; IS1381 transposase protein A 973229 1013769 SAG0965 Streptococcus agalactiae 2603V/R IS1381 transposase protein A NP_687977.1 972846 D 208435 CDS NP_687978.1 22537127 1013770 973262..973651 1 NC_004116.1 identified by match to PFAM protein family HMM PF01609; IS1381 transposase protein B 973651 1013770 SAG0966 Streptococcus agalactiae 2603V/R IS1381 transposase protein B NP_687978.1 973262 D 208435 CDS NP_687979.1 22537128 1013771 complement(973717..975279) 1 NC_004116.1 contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway; GMP synthase 975279 guaA 1013771 guaA Streptococcus agalactiae 2603V/R GMP synthase NP_687979.1 973717 R 208435 CDS NP_687980.1 22537129 1013772 975492..976190 1 NC_004116.1 identified by match to PFAM protein family HMM PF00392; GntR family transcriptional regulator 976190 1013772 SAG0968 Streptococcus agalactiae 2603V/R GntR family transcriptional regulator NP_687980.1 975492 D 208435 CDS NP_687981.1 22537130 1013773 976304..977638 1 NC_004116.1 TrmFO; Gid; glucose-inhibited division protein; similar to GidA; the gene from Bacillus subtilis encodes a tRNA-methyltransferase that utilizes folate as the carbon donor and bound flavin as reductant; modifies tRNA at position 54 (uridine) of the T-psi loop to form a C5-methyluridine; tRNA (uracil-5-)-methyltransferase Gid 977638 gid 1013773 gid Streptococcus agalactiae 2603V/R tRNA (uracil-5-)-methyltransferase Gid NP_687981.1 976304 D 208435 CDS NP_687982.1 22537131 1013774 977716..978459 1 NC_004116.1 identified by match to PFAM protein family HMM PF00583; acetyltransferase 978459 1013774 SAG0970 Streptococcus agalactiae 2603V/R acetyltransferase NP_687982.1 977716 D 208435 CDS NP_687983.1 22537132 1013775 978592..979440 1 NC_004116.1 identified by match to PFAM protein family HMM PF03180; The product of this gene was detected by Western blot analysis. For details on the method see Tettelin et al. 2002.; hypothetical protein 979440 1013775 SAG0971 Streptococcus agalactiae 2603V/R hypothetical protein NP_687983.1 978592 D 208435 CDS NP_687984.1 22537133 1013777 980127..981089 1 NC_004116.1 nisin-resistance protein 981089 1013777 SAG0973 Streptococcus agalactiae 2603V/R nisin-resistance protein NP_687984.1 980127 D 208435 CDS NP_687985.1 22537134 1013778 981115..981867 1 NC_004116.1 identified by match to PFAM protein family HMM PF00005; ABC transporter ATP-binding protein 981867 1013778 SAG0974 Streptococcus agalactiae 2603V/R ABC transporter ATP-binding protein NP_687985.1 981115 D 208435 CDS NP_687986.1 22537135 1013779 981869..983824 1 NC_004116.1 similar to OMNI:NTL01LL1789; identified by sequence similarity; ABC transporter permease 983824 1013779 SAG0975 Streptococcus agalactiae 2603V/R ABC transporter permease NP_687986.1 981869 D 208435 CDS NP_687987.1 22537136 1013780 983934..984602 1 NC_004116.1 identified by match to PFAM protein family HMM PF00072; DNA-binding response regulator 984602 1013780 SAG0976 Streptococcus agalactiae 2603V/R DNA-binding response regulator NP_687987.1 983934 D 208435 CDS NP_687988.1 22537137 1013781 984599..985537 1 NC_004116.1 identified by match to PFAM protein family HMM PF00512; sensor histidine kinase 985537 1013781 SAG0977 Streptococcus agalactiae 2603V/R sensor histidine kinase NP_687988.1 984599 D 208435 CDS NP_687989.1 22537138 1013782 complement(985580..986650) 1 NC_004116.1 site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; cell division protein FtsK may regulate the XerS; site-specific tyrosine recombinase XerS 986650 xerS 1013782 xerS Streptococcus agalactiae 2603V/R site-specific tyrosine recombinase XerS NP_687989.1 985580 R 208435 CDS NP_687990.1 22537139 1013783 987103..988764 1 NC_004116.1 identified by match to PFAM protein family HMM PF00496; ABC transporter substrate-binding protein 988764 1013783 SAG0979 Streptococcus agalactiae 2603V/R ABC transporter substrate-binding protein NP_687990.1 987103 D 208435 CDS NP_687991.1 22537140 1013784 complement(988797..989570) 1 NC_004116.1 hypothetical protein 989570 1013784 SAG0980 Streptococcus agalactiae 2603V/R hypothetical protein NP_687991.1 988797 R 208435 CDS NP_687992.1 22537141 1013785 complement(989560..990246) 1 NC_004116.1 similar to GP:11055964; identified by sequence similarity; satD protein 990246 1013785 SAG0981 Streptococcus agalactiae 2603V/R satD protein NP_687992.1 989560 R 208435 CDS NP_687993.1 22537142 1013786 complement(990313..991878) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00448; signal recognition particle protein Ffh 991878 ffh 1013786 ffh Streptococcus agalactiae 2603V/R signal recognition particle protein Ffh NP_687993.1 990313 R 208435 CDS NP_687994.1 22537143 1013787 complement(991896..992228) 1 NC_004116.1 DNA-binding protein 992228 1013787 SAG0983 Streptococcus agalactiae 2603V/R DNA-binding protein NP_687994.1 991896 R 208435 CDS NP_687995.1 22537144 1013788 complement(992317..993630) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00512; sensor histidine kinase CiaH 993630 1013788 SAG0984 Streptococcus agalactiae 2603V/R sensor histidine kinase CiaH NP_687995.1 992317 R 208435 CDS NP_687996.1 22537145 1013789 complement(993614..994294) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00072; DNA-binding response regulator CiaR 994294 ciaR 1013789 ciaR Streptococcus agalactiae 2603V/R DNA-binding response regulator CiaR NP_687996.1 993614 R 208435 CDS NP_687997.1 22537146 1013790 complement(994456..997005) 1 NC_004116.1 identified by match to PFAM protein family HMM PF01433; aminopeptidase 997005 pepN 1013790 pepN Streptococcus agalactiae 2603V/R aminopeptidase NP_687997.1 994456 R 208435 CDS NP_687998.1 22537147 1013791 complement(997151..997804) 1 NC_004116.1 identified by match to PFAM protein family HMM PF01895; phosphate transport system regulatory protein PhoU 997804 phoU 1013791 phoU Streptococcus agalactiae 2603V/R phosphate transport system regulatory protein PhoU NP_687998.1 997151 R 208435 CDS NP_687999.1 22537148 1013792 complement(997838..998596) 1 NC_004116.1 ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation; phosphate transporter ATP-binding protein 998596 1013792 SAG0988 Streptococcus agalactiae 2603V/R phosphate transporter ATP-binding protein NP_687999.1 997838 R 208435 CDS NP_688000.1 22537149 1013793 complement(998608..999411) 1 NC_004116.1 ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation; phosphate transporter ATP-binding protein 999411 1013793 SAG0989 Streptococcus agalactiae 2603V/R phosphate transporter ATP-binding protein NP_688000.1 998608 R 208435 CDS NP_688001.1 22537150 1013794 complement(999423..1000310) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00528; phosphate ABC transporter permease 1000310 1013794 SAG0990 Streptococcus agalactiae 2603V/R phosphate ABC transporter permease NP_688001.1 999423 R 208435 CDS NP_688002.1 22537151 1013795 complement(1000300..1001217) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00528; phosphate ABC transporter permease 1001217 1013795 SAG0991 Streptococcus agalactiae 2603V/R phosphate ABC transporter permease NP_688002.1 1000300 R 208435 CDS NP_688003.1 22537152 1013796 complement(1001263..1002123) 1 NC_004116.1 identified by match to PFAM protein family HMM PF01449; phosphate ABC transporter substrate-binding protein 1002123 1013796 SAG0992 Streptococcus agalactiae 2603V/R phosphate ABC transporter substrate-binding protein NP_688003.1 1001263 R 208435 CDS NP_688004.1 22537153 1013797 complement(1002308..1003618) 1 NC_004116.1 identified by match to PFAM protein family HMM PF01189; NOL1/NOP2/sun family protein 1003618 1013797 SAG0993 Streptococcus agalactiae 2603V/R NOL1/NOP2/sun family protein NP_688004.1 1002308 R 208435 CDS NP_688005.1 22537154 1013798 complement(1003686..1004450) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00459; inositol monophosphatase 1004450 1013798 SAG0994 Streptococcus agalactiae 2603V/R inositol monophosphatase NP_688005.1 1003686 R 208435 CDS NP_688006.1 22537155 1013799 complement(1004440..1004721) 1 NC_004116.1 hypothetical protein 1004721 1013799 SAG0995 Streptococcus agalactiae 2603V/R hypothetical protein NP_688006.1 1004440 R 208435 CDS NP_688007.1 22537156 1013800 complement(1004714..1005127) 1 NC_004116.1 the anti-alpha factor Spx interacts with RNA polymerase alpha subunit C-terminal domain in a region that interacts with the sigma 70 subunit and may interfere with activation of promoters; in Bacillus subtilis this protein is a substrate for ClpXP protease; blocks transcription of the competence regulatory gene encoded by the srf operon; regulates a number of genes involved in thiol homeostasis including trxA and trxB; monomeric member of ArsC family of proteins; does not bind DNA; contains a disulfide bond between C10 and C13 which may sense disulfide stress; Spx family transcriptional regulator 1005127 spxA 1013800 spxA Streptococcus agalactiae 2603V/R Spx family transcriptional regulator NP_688007.1 1004714 R 208435 CDS NP_688008.1 22537157 1013801 complement(1005170..1006102) 1 NC_004116.1 catalyzes the formation of FMN from riboflavin and the formation of FAD from FMN; in Bacillus the ribC gene has both flavokinase and FAD synthetase activities; bifunctional riboflavin kinase/FMN adenylyltransferase 1006102 1013801 SAG0997 Streptococcus agalactiae 2603V/R bifunctional riboflavin kinase/FMN adenylyltransferase NP_688008.1 1005170 R 208435 CDS NP_688009.1 22537158 1013802 complement(1006115..1006999) 1 NC_004116.1 catalyzes isomerization of specific uridines in RNA to pseudouridine; responsible for residues in T loops of many tRNAs; tRNA pseudouridine synthase B 1006999 truB 1013802 truB Streptococcus agalactiae 2603V/R tRNA pseudouridine synthase B NP_688009.1 1006115 R 208435 CDS NP_688010.1 22537159 1013803 complement(1007091..1007522) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00583; acetyltransferase 1007522 1013803 SAG0999 Streptococcus agalactiae 2603V/R acetyltransferase NP_688010.1 1007091 R 208435 CDS NP_688011.1 22537160 1013804 complement(1007535..1008806) 1 NC_004116.1 hypothetical protein 1008806 1013804 SAG1000 Streptococcus agalactiae 2603V/R hypothetical protein NP_688011.1 1007535 R 208435 CDS NP_688012.1 22537161 1013805 complement(1008840..1009430) 1 NC_004116.1 hypothetical protein 1009430 1013805 SAG1001 Streptococcus agalactiae 2603V/R hypothetical protein NP_688012.1 1008840 R 208435 CDS NP_688013.1 22537162 1013806 complement(1009537..1010415) 1 NC_004116.1 identified by match to PFAM protein family HMM PF02517; protease 1010415 1013806 SAG1002 Streptococcus agalactiae 2603V/R protease NP_688013.1 1009537 R 208435 CDS NP_688014.1 22537163 1013807 complement(1010521..1013151) 1 NC_004116.1 identified by match to PFAM protein family HMM PF02687; permease 1013151 1013807 SAG1003 Streptococcus agalactiae 2603V/R permease NP_688014.1 1010521 R 208435 CDS NP_688015.1 22537164 1013808 complement(1013163..1013864) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00005; ABC transporter ATP-binding protein 1013864 1013808 SAG1004 Streptococcus agalactiae 2603V/R ABC transporter ATP-binding protein NP_688015.1 1013163 R 208435 CDS NP_688016.1 22537165 1013809 complement(1014001..1016121) 1 NC_004116.1 catalyzes the ATP-dependent breakage of single-stranded DNA followed by passage and rejoining, maintains net negative superhelicity; DNA topoisomerase I 1016121 topA 1013809 topA Streptococcus agalactiae 2603V/R DNA topoisomerase I NP_688016.1 1014001 R 208435 CDS NP_688017.1 22537166 1013810 complement(1016216..1017058) 1 NC_004116.1 identified by match to PFAM protein family HMM PF02481; DprA/SMF protein DNA processing factor 1017058 dprA 1013810 dprA Streptococcus agalactiae 2603V/R DprA/SMF protein DNA processing factor NP_688017.1 1016216 R 208435 CDS NP_688018.1 22537167 1013811 complement(1017196..1018224) 1 NC_004116.1 identified by match to PFAM protein family HMM PF01497; iron-compound ABC transporter iron-compound-binding protein 1018224 1013811 SAG1007 Streptococcus agalactiae 2603V/R iron-compound ABC transporter iron-compound-binding protein NP_688018.1 1017196 R 208435 CDS NP_688019.1 22537168 1013812 complement(1018286..1019047) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00005; iron ABC transporter ATP-binding protein 1019047 1013812 SAG1008 Streptococcus agalactiae 2603V/R iron ABC transporter ATP-binding protein NP_688019.1 1018286 R 208435 CDS NP_688020.1 22537169 1013813 complement(1019044..1020018) 1 NC_004116.1 identified by match to PFAM protein family HMM PF01032; iron ABC transporter permease 1020018 1013813 SAG1009 Streptococcus agalactiae 2603V/R iron ABC transporter permease NP_688020.1 1019044 R 208435 CDS NP_688021.1 22537170 1013814 complement(1020015..1020977) 1 NC_004116.1 identified by match to PFAM protein family HMM PF01032; iron ABC transporter permease 1020977 1013814 SAG1010 Streptococcus agalactiae 2603V/R iron ABC transporter permease NP_688021.1 1020015 R 208435 CDS NP_688022.1 22537171 1013815 complement(1021216..1021764) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00132; acetyltransferase 1021764 1013815 SAG1011 Streptococcus agalactiae 2603V/R acetyltransferase NP_688022.1 1021216 R 208435 CDS NP_688023.1 22537172 1013816 complement(1021785..1022546) 1 NC_004116.1 RNH2; RNase HII; binds manganese; endonuclease which specifically degrades the RNA of RNA-DNA hybrids; ribonuclease HII 1022546 rnhB 1013816 rnhB Streptococcus agalactiae 2603V/R ribonuclease HII NP_688023.1 1021785 R 208435 CDS NP_688024.1 22537173 1013817 complement(1022533..1023384) 1 NC_004116.1 essential GTPase; functions in ribosome assembly; binds a unique part of the 23S rRNA; interacts with ribosomal protein L25(Ctc); ribosomal biogenesis GTPase 1023384 rbgA 1013817 rbgA Streptococcus agalactiae 2603V/R ribosomal biogenesis GTPase NP_688024.1 1022533 R 208435 CDS NP_688025.1 22537174 1013818 complement(1023660..1024232) 1 NC_004116.1 identified by Glimmer2; The product of this gene was detected by Western blot analysis. For details on the method see Tettelin et al. 2002.; hypothetical protein 1024232 1013818 SAG1014 Streptococcus agalactiae 2603V/R hypothetical protein NP_688025.1 1023660 R 208435 CDS NP_688026.1 22537175 1013819 complement(1024433..1025917) 1 NC_004116.1 carbon starvation protein CstA 1025917 1013819 SAG1015 Streptococcus agalactiae 2603V/R carbon starvation protein CstA NP_688026.1 1024433 R 208435 CDS NP_688027.1 22537176 1013820 complement(1026073..1026807) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00072; response regulator 1026807 1013820 SAG1016 Streptococcus agalactiae 2603V/R response regulator NP_688027.1 1026073 R 208435 CDS NP_688028.1 22537177 1013821 complement(1026819..1028558) 1 NC_004116.1 identified by match to PFAM protein family HMM PF02518; sensor histidine kinase 1028558 1013821 SAG1017 Streptococcus agalactiae 2603V/R sensor histidine kinase NP_688028.1 1026819 R 208435 CDS NP_688029.1 22537178 1013822 complement(1029094..1029216) 1 NC_004116.1 lipoprotein 1029216 1013822 SAG1018 Streptococcus agalactiae 2603V/R lipoprotein NP_688029.1 1029094 R 208435 CDS NP_688030.1 22537179 1013823 complement(1029739..1029858) 1 NC_004116.1 hypothetical protein 1029858 1013823 SAG1019 Streptococcus agalactiae 2603V/R hypothetical protein NP_688030.1 1029739 R 208435 CDS NP_688031.1 22537180 1013824 complement(1030102..1030785) 1 NC_004116.1 lipoprotein 1030785 1013824 SAG1020 Streptococcus agalactiae 2603V/R lipoprotein NP_688031.1 1030102 R 208435 CDS NP_688032.1 22537181 1013825 complement(1030871..1031194) 1 NC_004116.1 hypothetical protein 1031194 1013825 SAG1021 Streptococcus agalactiae 2603V/R hypothetical protein NP_688032.1 1030871 R 208435 CDS NP_688033.1 22537182 1013826 complement(1031542..1032075) 1 NC_004116.1 hypothetical protein 1032075 1013826 SAG1022 Streptococcus agalactiae 2603V/R hypothetical protein NP_688033.1 1031542 R 208435 CDS NP_688034.1 22537183 1013827 complement(1032087..1032233) 1 NC_004116.1 hypothetical protein 1032233 1013827 SAG1023 Streptococcus agalactiae 2603V/R hypothetical protein NP_688034.1 1032087 R 208435 CDS NP_688035.1 22537184 1013828 complement(1032230..1032781) 1 NC_004116.1 lipoprotein 1032781 1013828 SAG1024 Streptococcus agalactiae 2603V/R lipoprotein NP_688035.1 1032230 R 208435 CDS NP_688036.1 22537185 1013829 complement(1032786..1033235) 1 NC_004116.1 hypothetical protein 1033235 1013829 SAG1025 Streptococcus agalactiae 2603V/R hypothetical protein NP_688036.1 1032786 R 208435 CDS NP_688037.1 22537186 1013831 complement(1035253..1035507) 1 NC_004116.1 hypothetical protein 1035507 1013831 SAG1027 Streptococcus agalactiae 2603V/R hypothetical protein NP_688037.1 1035253 R 208435 CDS NP_688038.1 22537187 1013832 complement(1035528..1036118) 1 NC_004116.1 hypothetical protein 1036118 1013832 SAG1028 Streptococcus agalactiae 2603V/R hypothetical protein NP_688038.1 1035528 R 208435 CDS NP_688039.1 22537188 1013833 complement(1036132..1036437) 1 NC_004116.1 hypothetical protein 1036437 1013833 SAG1029 Streptococcus agalactiae 2603V/R hypothetical protein NP_688039.1 1036132 R 208435 CDS NP_688040.1 22537189 1013834 complement(1036566..1037480) 1 NC_004116.1 similar to OMNI:SA0643; identified by sequence similarity; The product of this gene was detected by Western blot analysis. For details on the method see Tettelin et al. 2002.; hypothetical protein 1037480 1013834 SAG1030 Streptococcus agalactiae 2603V/R hypothetical protein NP_688040.1 1036566 R 208435 CDS NP_688041.1 22537190 1013835 complement(1037483..1037845) 1 NC_004116.1 similar to GB:L13925 PID:466482; identified by sequence similarity; hypothetical protein 1037845 1013835 SAG1031 Streptococcus agalactiae 2603V/R hypothetical protein NP_688041.1 1037483 R 208435 CDS NP_688042.1 22537191 1013836 complement(1037950..1038207) 1 NC_004116.1 hypothetical protein 1038207 1013836 SAG1032 Streptococcus agalactiae 2603V/R hypothetical protein NP_688042.1 1037950 R 208435 CDS NP_688043.1 22537192 1013837 complement(1038221..1042150) 1 NC_004116.1 identified by match to PFAM protein family HMM PF01580; DNA translocase FtsK 1042150 1013837 SAG1033 Streptococcus agalactiae 2603V/R DNA translocase FtsK NP_688043.1 1038221 R 208435 CDS NP_688044.1 22537193 1013838 complement(1042461..1042628) 1 NC_004116.1 hypothetical protein 1042628 1013838 SAG1034 Streptococcus agalactiae 2603V/R hypothetical protein NP_688044.1 1042461 R 208435 CDS NP_688045.1 22537194 1013839 complement(1042635..1043909) 1 NC_004116.1 hypothetical protein 1043909 1013839 SAG1035 Streptococcus agalactiae 2603V/R hypothetical protein NP_688045.1 1042635 R 208435 CDS NP_688046.1 22537195 1013840 complement(1043909..1044151) 1 NC_004116.1 hypothetical protein 1044151 1013840 SAG1036 Streptococcus agalactiae 2603V/R hypothetical protein NP_688046.1 1043909 R 208435 CDS NP_688047.1 22537196 1013841 complement(1044135..1044608) 1 NC_004116.1 hypothetical protein 1044608 1013841 SAG1037 Streptococcus agalactiae 2603V/R hypothetical protein NP_688047.1 1044135 R 208435 CDS NP_688048.1 22537197 1013842 complement(1044617..1047628) 1 NC_004116.1 phage infection protein 1047628 1013842 SAG1038 Streptococcus agalactiae 2603V/R phage infection protein NP_688048.1 1044617 R 208435 CDS NP_688049.1 22537198 1013843 complement(1047710..1048000) 1 NC_004116.1 hypothetical protein 1048000 1013843 SAG1039 Streptococcus agalactiae 2603V/R hypothetical protein NP_688049.1 1047710 R 208435 CDS NP_688050.1 22537199 1013844 complement(1048117..1048899) 1 NC_004116.1 similar to GP:14588952; identified by sequence similarity; hypothetical protein 1048899 1013844 SAG1040 Streptococcus agalactiae 2603V/R hypothetical protein NP_688050.1 1048117 R 208435 CDS NP_688051.1 22537200 1013845 complement(1048896..1049219) 1 NC_004116.1 hypothetical protein 1049219 1013845 SAG1041 Streptococcus agalactiae 2603V/R hypothetical protein NP_688051.1 1048896 R 208435 CDS NP_688052.1 22537201 1013846 complement(1049346..1052528) 1 NC_004116.1 four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate; CarB is responsible for the amidotransferase activity; carbamoyl phosphate synthase large subunit 1052528 carB 1013846 carB Streptococcus agalactiae 2603V/R carbamoyl phosphate synthase large subunit NP_688052.1 1049346 R 208435 CDS NP_688053.1 22537202 1013847 complement(1052559..1053635) 1 NC_004116.1 catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers; carbamoyl phosphate synthase small subunit 1053635 carA-1 1013847 carA-1 Streptococcus agalactiae 2603V/R carbamoyl phosphate synthase small subunit NP_688053.1 1052559 R 208435 CDS NP_688054.1 22537203 1013848 complement(1053649..1054572) 1 NC_004116.1 catalyzes the transfer of the carbamoyl moiety from carbamoyl phosphate to L- aspartate in pyrimidine biosynthesis; aspartate carbamoyltransferase 1054572 pyrB 1013848 pyrB Streptococcus agalactiae 2603V/R aspartate carbamoyltransferase NP_688054.1 1053649 R 208435 CDS NP_688055.1 22537204 1013849 complement(1054737..1056029) 1 NC_004116.1 catalyzes the formation of N-carbamoyl-L-aspartate from (S)-dihydroorotate in pyrimidine biosynthesis; dihydroorotase 1056029 pyrC 1013849 pyrC Streptococcus agalactiae 2603V/R dihydroorotase NP_688055.1 1054737 R 208435 CDS NP_688056.1 22537205 1013850 complement(1056041..1056670) 1 NC_004116.1 involved in fifth step of pyrimidine biosynthesis; converts orotidine 5'-phosphate and diphosphate to orotate and 5-phospho-alpha-D-ribose 1-diphosphate; orotate phosphoribosyltransferase 1056670 pyrE 1013850 pyrE Streptococcus agalactiae 2603V/R orotate phosphoribosyltransferase NP_688056.1 1056041 R 208435 CDS NP_688057.1 22537206 1013851 complement(1056683..1057384) 1 NC_004116.1 OMP decarboxylase; OMPDCase; OMPdecase; type 1 subfamily; involved in last step of pyrimidine biosynthesis; converts orotidine 5'-phosphate to UMP and carbon dioxide; OMP decarboxylase; OMPDCase; OMPdecase; orotidine 5'-phosphate decarboxylase 1057384 pyrF 1013851 pyrF Streptococcus agalactiae 2603V/R orotidine 5'-phosphate decarboxylase NP_688057.1 1056683 R 208435 CDS NP_688058.1 22537207 1013852 complement(1057597..1058829) 1 NC_004116.1 similar to OMNI:NTL01CA2266; identified by sequence similarity; hypothetical protein 1058829 1013852 SAG1048 Streptococcus agalactiae 2603V/R hypothetical protein NP_688058.1 1057597 R 208435 CDS NP_688059.1 22537208 1013853 complement(1058869..1060410) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00005; ABC transporter ATP-binding protein 1060410 1013853 SAG1049 Streptococcus agalactiae 2603V/R ABC transporter ATP-binding protein NP_688059.1 1058869 R 208435 CDS NP_688060.1 22537209 1013855 complement(1061049..1062125) 1 NC_004116.1 catalyzes the formation of 4-aspartyl phosphate from aspartate 4-semialdehyde; aspartate-semialdehyde dehydrogenase 1062125 asd 1013855 asd Streptococcus agalactiae 2603V/R aspartate-semialdehyde dehydrogenase NP_688060.1 1061049 R 208435 CDS NP_688061.1 22537210 1013856 complement(1062335..1062478) 1 NC_004116.1 cell wall surface anchor family protein 1062478 1013856 SAG1052 Streptococcus agalactiae 2603V/R cell wall surface anchor family protein NP_688061.1 1062335 R 208435 CDS NP_688062.1 22537211 1013857 1063089..1063181 1 NC_004116.1 hypothetical protein 1063181 1013857 SAG1053 Streptococcus agalactiae 2603V/R hypothetical protein NP_688062.1 1063089 D 208435 CDS NP_688063.2 545902391 1013858 complement(1063395..1064870) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00614; cardiolipin synthetase 1064870 cls 1013858 cls Streptococcus agalactiae 2603V/R cardiolipin synthetase NP_688063.2 1063395 R 208435 CDS NP_688064.1 22537213 1013859 complement(1065109..1066779) 1 NC_004116.1 catalyzes the formation of 10-formyltetrahydrofolate from formate and tetrahydrofolate; formate--tetrahydrofolate ligase 1066779 fhs 1013859 fhs Streptococcus agalactiae 2603V/R formate--tetrahydrofolate ligase NP_688064.1 1065109 R 208435 CDS NP_688065.1 22537214 1013860 complement(1066868..1067887) 1 NC_004116.1 identified by match to PFAM protein family HMM PF02539; lipoate-protein ligase A 1067887 lplA-2 1013860 lplA-2 Streptococcus agalactiae 2603V/R lipoate-protein ligase A NP_688065.1 1066868 R 208435 CDS NP_688066.1 22537215 1013861 complement(1067914..1068792) 1 NC_004116.1 hypothetical protein 1068792 1013861 SAG1057 Streptococcus agalactiae 2603V/R hypothetical protein NP_688066.1 1067914 R 208435 CDS NP_688067.1 22537216 1013862 complement(1068761..1069579) 1 NC_004116.1 hypothetical protein 1069579 1013862 SAG1058 Streptococcus agalactiae 2603V/R hypothetical protein NP_688067.1 1068761 R 208435 CDS NP_688068.1 22537217 1013863 complement(1069572..1069904) 1 NC_004116.1 identified by match to PFAM protein family HMM PF01597; glycine cleavage system H protein 1069904 1013863 SAG1059 Streptococcus agalactiae 2603V/R glycine cleavage system H protein NP_688068.1 1069572 R 208435 CDS NP_688069.1 22537218 1013864 complement(1069933..1070919) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00296; luciferase family protein 1070919 1013864 SAG1060 Streptococcus agalactiae 2603V/R luciferase family protein NP_688069.1 1069933 R 208435 CDS NP_688070.1 22537219 1013865 complement(1070916..1072115) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00724; oxidoreductase, FMN-binding 1072115 1013865 SAG1061 Streptococcus agalactiae 2603V/R oxidoreductase, FMN-binding NP_688070.1 1070916 R 208435 CDS NP_688071.1 22537220 1013866 complement(1072108..1072956) 1 NC_004116.1 hypothetical protein 1072956 1013866 SAG1062 Streptococcus agalactiae 2603V/R hypothetical protein NP_688071.1 1072108 R 208435 CDS NP_688072.1 22537221 1013867 1073098..1073784 1 NC_004116.1 similar to GB:L77117 PID:1591587; identified by sequence similarity; phosphopantothenate--cysteine ligase 1073784 1013867 SAG1063 Streptococcus agalactiae 2603V/R phosphopantothenate--cysteine ligase NP_688072.1 1073098 D 208435 CDS NP_688073.1 22537222 1013868 1073777..1074319 1 NC_004116.1 decarboxylates 4-phosphopantothenoylcysteine to form 4'-phosphopantotheine.; phosphopantothenoylcysteine decarboxylase 1074319 1013868 SAG1064 Streptococcus agalactiae 2603V/R phosphopantothenoylcysteine decarboxylase NP_688073.1 1073777 D 208435 CDS NP_688074.1 22537223 1013869 1074365..1074937 1 NC_004116.1 similar to OMNI:NTL01SPL0962; identified by sequence similarity; hypothetical protein 1074937 1013869 SAG1065 Streptococcus agalactiae 2603V/R hypothetical protein NP_688074.1 1074365 D 208435 CDS NP_688075.1 22537224 1013870 1075047..1076765 1 NC_004116.1 identified by match to PFAM protein family HMM PF00408; phosphoglucomutase 1076765 pgm 1013870 pgm Streptococcus agalactiae 2603V/R phosphoglucomutase NP_688075.1 1075047 D 208435 CDS NP_688076.1 22537225 1013871 1076837..1077373 1 NC_004116.1 IS861, transposase OrfA 1077373 1013871 SAG1067 Streptococcus agalactiae 2603V/R IS861, transposase OrfA NP_688076.1 1076837 D 208435 CDS NP_688077.1 22537226 1013872 1077349..1078182 1 NC_004116.1 identified by match to PFAM protein family HMM PF00665; IS861, transposase OrfB 1078182 1013872 SAG1068 Streptococcus agalactiae 2603V/R IS861, transposase OrfB NP_688077.1 1077349 D 208435 CDS NP_688078.1 22537227 1013873 complement(1078264..1078461) 1 NC_004116.1 hypothetical protein 1078461 1013873 SAG1069 Streptococcus agalactiae 2603V/R hypothetical protein NP_688078.1 1078264 R 208435 CDS NP_688079.1 22537228 1013874 complement(1078475..1080208) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00005; ABC transporter ATP-binding protein/permease 1080208 1013874 SAG1070 Streptococcus agalactiae 2603V/R ABC transporter ATP-binding protein/permease NP_688079.1 1078475 R 208435 CDS NP_688080.1 22537229 1013875 complement(1080209..1081930) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00005; ABC transporter ATP-binding protein/permease 1081930 1013875 SAG1071 Streptococcus agalactiae 2603V/R ABC transporter ATP-binding protein/permease NP_688080.1 1080209 R 208435 CDS NP_688081.1 22537230 1013876 complement(1081942..1082544) 1 NC_004116.1 hypothetical protein 1082544 1013876 SAG1072 Streptococcus agalactiae 2603V/R hypothetical protein NP_688081.1 1081942 R 208435 CDS NP_688082.1 22537231 1013877 complement(1082546..1083523) 1 NC_004116.1 hypothetical protein 1083523 1013877 SAG1073 Streptococcus agalactiae 2603V/R hypothetical protein NP_688082.1 1082546 R 208435 CDS NP_688083.1 22537232 1013878 complement(1083528..1084784) 1 NC_004116.1 catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate; serine hydroxymethyltransferase 1084784 glyA 1013878 glyA Streptococcus agalactiae 2603V/R serine hydroxymethyltransferase NP_688083.1 1083528 R 208435 CDS NP_688084.1 22537233 1013879 complement(1084876..1085427) 1 NC_004116.1 identified by match to PFAM protein family HMM PF01300; Sua5/YciO/YrdC/YwlC family protein 1085427 1013879 SAG1075 Streptococcus agalactiae 2603V/R Sua5/YciO/YrdC/YwlC family protein NP_688084.1 1084876 R 208435 CDS NP_688085.1 22537234 1013880 complement(1085465..1086295) 1 NC_004116.1 identified by match to TIGR protein family HMM TIGR00536; HemK family modification methylase 1086295 1013880 SAG1076 Streptococcus agalactiae 2603V/R HemK family modification methylase NP_688085.1 1085465 R 208435 CDS NP_688086.1 22537235 1013881 complement(1086295..1087374) 1 NC_004116.1 recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2; peptide chain release factor 1 1087374 prfA 1013881 prfA Streptococcus agalactiae 2603V/R peptide chain release factor 1 NP_688086.1 1086295 R 208435 CDS NP_688087.1 22537236 1013882 complement(1087409..1087978) 1 NC_004116.1 catalyzes the formation of thymidine 5'-phosphate from thymidine; thymidine kinase 1087978 tdk 1013882 tdk Streptococcus agalactiae 2603V/R thymidine kinase NP_688087.1 1087409 R 208435 CDS NP_688088.1 22537237 1013883 1088116..1088298 1 NC_004116.1 4-OT; member of subfamily 5; forms a dimer; the function in the Escherichia coli cell is unknown; 4-oxalocrotonate tautomerase 1088298 xylM 1013883 xylM Streptococcus agalactiae 2603V/R 4-oxalocrotonate tautomerase NP_688088.1 1088116 D 208435 CDS NP_688089.1 22537238 1013884 complement(1088274..1088417) 1 NC_004116.1 hypothetical protein 1088417 1013884 SAG1080 Streptococcus agalactiae 2603V/R hypothetical protein NP_688089.1 1088274 R 208435 CDS NP_688090.1 22537239 1013885 1088447..1089385 1 NC_004116.1 identified by match to PFAM protein family HMM PF02424; ApbE family protein 1089385 1013885 SAG1081 Streptococcus agalactiae 2603V/R ApbE family protein NP_688090.1 1088447 D 208435 CDS NP_688091.1 22537240 1013886 1089403..1090005 1 NC_004116.1 hypothetical protein 1090005 1013886 SAG1082 Streptococcus agalactiae 2603V/R hypothetical protein NP_688091.1 1089403 D 208435 CDS NP_688092.1 22537241 1013887 1090029..1091264 1 NC_004116.1 hypothetical protein 1091264 1013887 SAG1083 Streptococcus agalactiae 2603V/R hypothetical protein NP_688092.1 1090029 D 208435 CDS NP_688093.1 22537242 1013888 1091363..1092151 1 NC_004116.1 identified by match to PFAM protein family HMM PF01226; formate/nitrite transporter family protein 1092151 1013888 SAG1084 Streptococcus agalactiae 2603V/R formate/nitrite transporter family protein NP_688093.1 1091363 D 208435 CDS NP_688094.1 22537243 1013889 complement(1092250..1093524) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00860; xanthine permease 1093524 pbuX 1013889 pbuX Streptococcus agalactiae 2603V/R xanthine permease NP_688094.1 1092250 R 208435 CDS NP_688095.1 22537244 1013890 complement(1093524..1094105) 1 NC_004116.1 Catalyzes the transfer of the phosphoribosyl moiety from 5-phospho--D-ribosyl-1-pyrophosphate (PRib-PP) to the 6-oxo-guanine and -xanthine; xanthine phosphoribosyltransferase 1094105 xpt 1013890 xpt Streptococcus agalactiae 2603V/R xanthine phosphoribosyltransferase NP_688095.1 1093524 R 208435 CDS NP_688096.1 22537245 1013891 complement(1094361..1095344) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00478; guanosine 5'-monophosphate oxidoreductase 1095344 guaC 1013891 guaC Streptococcus agalactiae 2603V/R guanosine 5'-monophosphate oxidoreductase NP_688096.1 1094361 R 208435 CDS NP_688097.1 22537246 1013892 complement(1095548..1096888) 1 NC_004116.1 EmrB/QacA family drug resistance transporter 1096888 1013892 SAG1088 Streptococcus agalactiae 2603V/R EmrB/QacA family drug resistance transporter NP_688097.1 1095548 R 208435 CDS NP_688098.1 22537247 1013893 1097159..1097851 1 NC_004116.1 hypothetical protein 1097851 1013893 SAG1089 Streptococcus agalactiae 2603V/R hypothetical protein NP_688098.1 1097159 D 208435 CDS NP_688099.1 22537248 1013894 complement(1097922..1099922) 1 NC_004116.1 identified by match to PFAM protein family HMM PF02705; potassium uptake protein 1099922 1013894 SAG1090 Streptococcus agalactiae 2603V/R potassium uptake protein NP_688099.1 1097922 R 208435 CDS NP_688100.1 22537249 1013895 complement(1100057..1100707) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00106; short chain dehydrogenase/reductase family oxidoreductase 1100707 1013895 SAG1091 Streptococcus agalactiae 2603V/R short chain dehydrogenase/reductase family oxidoreductase NP_688100.1 1100057 R 208435 CDS NP_688101.1 22537250 1013896 complement(1100881..1101873) 1 NC_004116.1 in Salmonella this enzyme is required for ethanolamine catabolism; has higher affinity for CoA than Pta; phosphotransacetylase 1101873 eutD 1013896 eutD Streptococcus agalactiae 2603V/R phosphotransacetylase NP_688101.1 1100881 R 208435 CDS NP_688102.1 22537251 1013897 complement(1101899..1102783) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00849; ribosomal large subunit pseudouridine synthase D 1102783 1013897 SAG1093 Streptococcus agalactiae 2603V/R ribosomal large subunit pseudouridine synthase D NP_688102.1 1101899 R 208435 CDS NP_688103.1 22537252 1013898 complement(1102780..1103616) 1 NC_004116.1 catalyzes the phosphorylation of NAD to NADP; inorganic polyphosphate/ATP-NAD kinase 1103616 ppnK 1013898 ppnK Streptococcus agalactiae 2603V/R inorganic polyphosphate/ATP-NAD kinase NP_688103.1 1102780 R 208435 CDS NP_688104.1 22537253 1013899 complement(1103591..1104262) 1 NC_004116.1 similar to OMNI:NTL01SPL0878; identified by sequence similarity; GTP pyrophosphokinase 1104262 1013899 SAG1095 Streptococcus agalactiae 2603V/R GTP pyrophosphokinase NP_688104.1 1103591 R 208435 CDS NP_688105.1 22537254 1013900 1104372..1104944 1 NC_004116.1 hypothetical protein 1104944 1013900 SAG1096 Streptococcus agalactiae 2603V/R hypothetical protein NP_688105.1 1104372 D 208435 CDS NP_688106.1 22537255 1013901 1105121..1106095 1 NC_004116.1 catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP; ribose-phosphate pyrophosphokinase 1106095 prsA-2 1013901 prsA-2 Streptococcus agalactiae 2603V/R ribose-phosphate pyrophosphokinase NP_688106.1 1105121 D 208435 CDS NP_688107.1 22537256 1013902 1106099..1107214 1 NC_004116.1 identified by match to PFAM protein family HMM PF00266; cysteine desulfurase 1107214 iscS-1 1013902 iscS-1 Streptococcus agalactiae 2603V/R cysteine desulfurase NP_688107.1 1106099 D 208435 CDS NP_688108.1 22537257 1013903 1107216..1107563 1 NC_004116.1 hypothetical protein 1107563 1013903 SAG1099 Streptococcus agalactiae 2603V/R hypothetical protein NP_688108.1 1107216 D 208435 CDS NP_688109.1 22537258 1013904 1107724..1108356 1 NC_004116.1 modulates transcription in response to the NADH/NAD(+) redox state; redox-sensing transcriptional repressor Rex 1108356 1013904 SAG1100 Streptococcus agalactiae 2603V/R redox-sensing transcriptional repressor Rex NP_688109.1 1107724 D 208435 CDS NP_688110.1 22537259 1013905 complement(1108369..1109049) 1 NC_004116.1 Involved in DNA double-strand break repair and recombination. Promotes the annealing of complementary single-stranded DNA and by simulation of RAD51 recombinase; DNA repair protein RadC 1109049 radC 1013905 radC Streptococcus agalactiae 2603V/R DNA repair protein RadC NP_688110.1 1108369 R 208435 CDS NP_688111.1 22537260 1013906 complement(1109145..1110278) 1 NC_004116.1 identified by match to PFAM protein family HMM PF01594; hypothetical protein 1110278 1013906 SAG1102 Streptococcus agalactiae 2603V/R hypothetical protein NP_688111.1 1109145 R 208435 CDS NP_688112.1 22537261 1013907 complement(1110369..1111805) 1 NC_004116.1 required for arbutin uptake and metabolism; 6-phospho-beta-glucosidase 1111805 arb 1013907 arb Streptococcus agalactiae 2603V/R 6-phospho-beta-glucosidase NP_688112.1 1110369 R 208435 CDS NP_688113.1 22537262 1013908 complement(1111968..1112582) 1 NC_004116.1 platelet activating factor 1112582 1013908 SAG1104 Streptococcus agalactiae 2603V/R platelet activating factor NP_688113.1 1111968 R 208435 CDS NP_688114.1 22537263 1013909 complement(1112683..1113504) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00702; HAD superfamily hydrolase 1113504 1013909 SAG1105 Streptococcus agalactiae 2603V/R HAD superfamily hydrolase NP_688114.1 1112683 R 208435 CDS NP_688115.1 22537264 1013910 1114129..1115058 1 NC_004116.1 identified by match to PFAM protein family HMM PF00165; AraC family transcriptional regulator 1115058 1013910 SAG1106 Streptococcus agalactiae 2603V/R AraC family transcriptional regulator NP_688115.1 1114129 D 208435 CDS NP_688116.1 22537265 1013911 complement(1115115..1116647) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00654; voltage-gated chloride channel family protein 1116647 1013911 SAG1107 Streptococcus agalactiae 2603V/R voltage-gated chloride channel family protein NP_688116.1 1115115 R 208435 CDS NP_688117.1 22537266 1013912 complement(1116756..1117829) 1 NC_004116.1 identified by match to PFAM protein family HMM PF01547; spermidine/putrescine ABC transporter spermidine/putrescine-binding protein 1117829 potD 1013912 potD Streptococcus agalactiae 2603V/R spermidine/putrescine ABC transporter spermidine/putrescine-binding protein NP_688117.1 1116756 R 208435 CDS NP_688118.1 22537267 1013913 complement(1117822..1118598) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00528; spermidine/putrescine ABC transporter permease 1118598 potC 1013913 potC Streptococcus agalactiae 2603V/R spermidine/putrescine ABC transporter permease NP_688118.1 1117822 R 208435 CDS NP_688119.1 22537268 1013914 complement(1118595..1119389) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00528; spermidine/putrescine ABC transporter permease 1119389 potB 1013914 potB Streptococcus agalactiae 2603V/R spermidine/putrescine ABC transporter permease NP_688119.1 1118595 R 208435 CDS NP_688120.1 22537269 1013915 complement(1119373..1120527) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00005; spermidine/putrescine ABC transporter ATP-binding protein 1120527 potA 1013915 potA Streptococcus agalactiae 2603V/R spermidine/putrescine ABC transporter ATP-binding protein NP_688120.1 1119373 R 208435 CDS NP_688121.1 22537270 1013916 complement(1120576..1121478) 1 NC_004116.1 catalyzes the reduction of UDP-N-acetylglucosamine enolpyruvate to form UDP-N-acetylmuramate in peptidoglycan biosynthesis; UDP-N-acetylenolpyruvoylglucosamine reductase 1121478 murB 1013916 murB Streptococcus agalactiae 2603V/R UDP-N-acetylenolpyruvoylglucosamine reductase NP_688121.1 1120576 R 208435 CDS NP_688122.1 22537271 1013917 complement(1121622..1122110) 1 NC_004116.1 identified by match to PFAM protein family HMM PF01288; 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase 1122110 folK 1013917 folK Streptococcus agalactiae 2603V/R 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase NP_688122.1 1121622 R 208435 CDS NP_688123.1 22537272 1013918 complement(1122107..1122469) 1 NC_004116.1 identified by match to PFAM protein family HMM PF02152; dihydroneopterin aldolase 1122469 folB 1013918 folB Streptococcus agalactiae 2603V/R dihydroneopterin aldolase NP_688123.1 1122107 R 208435 CDS NP_688124.1 22537273 1013919 complement(1122471..1123274) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00809; dihydropteroate synthase 1123274 folP 1013919 folP Streptococcus agalactiae 2603V/R dihydropteroate synthase NP_688124.1 1122471 R 208435 CDS NP_688125.1 22537274 1013920 complement(1123278..1123841) 1 NC_004116.1 involved in the first step of tetrahydrofolate biosynthesis; catalyzes the formation of formate and 2-amino-4-hydroxy-6-(erythro-1,2, 3-trihydroxypropyl)dihydropteridine triphosphate from GTP and water; forms a homopolymer; GTP cyclohydrolase I 1123841 folE 1013920 folE Streptococcus agalactiae 2603V/R GTP cyclohydrolase I NP_688125.1 1123278 R 208435 CDS NP_688126.1 22537275 1013921 complement(1123860..1125122) 1 NC_004116.1 identified by match to TIGR protein family HMM TIGR01499; folylpolyglutamate synthase 1125122 folC 1013921 folC Streptococcus agalactiae 2603V/R folylpolyglutamate synthase NP_688126.1 1123860 R 208435 CDS NP_688127.1 22537276 1013922 complement(1125124..1126011) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00892; rarD protein 1126011 rarD 1013922 rarD Streptococcus agalactiae 2603V/R rarD protein NP_688127.1 1125124 R 208435 CDS NP_688128.1 22537277 1013923 complement(1125998..1126864) 1 NC_004116.1 catalyzes the formation of O-phospho-L-homoserine from L-homoserine in threonine biosynthesis from asparate; homoserine kinase 1126864 thrB 1013923 thrB Streptococcus agalactiae 2603V/R homoserine kinase NP_688128.1 1125998 R 208435 CDS NP_688129.1 22537278 1013924 complement(1126866..1128149) 1 NC_004116.1 catalyzes the formation of L-aspartate 4-semialdehyde from L-homoserine; homoserine dehydrogenase 1128149 hom 1013924 hom Streptococcus agalactiae 2603V/R homoserine dehydrogenase NP_688129.1 1126866 R 208435 CDS NP_688130.1 22537279 1013925 1128326..1129213 1 NC_004116.1 identified by match to PFAM protein family HMM PF01522; polysaccharide deacetylase 1129213 1013925 SAG1121 Streptococcus agalactiae 2603V/R polysaccharide deacetylase NP_688130.1 1128326 D 208435 CDS NP_688131.1 22537280 1013926 complement(1129236..1130783) 1 NC_004116.1 identified by match to PFAM protein family HMM PF02028; transporter BCCT family protein 1130783 1013926 SAG1122 Streptococcus agalactiae 2603V/R transporter BCCT family protein NP_688131.1 1129236 R 208435 CDS NP_688132.1 22537281 1013927 complement(1130793..1130897) 1 NC_004116.1 hypothetical protein 1130897 1013927 SAG1123 Streptococcus agalactiae 2603V/R hypothetical protein NP_688132.1 1130793 R 208435 CDS NP_688133.1 22537282 1013928 complement(1130926..1132302) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00171; aldehyde dehydrogenase 1132302 1013928 SAG1124 Streptococcus agalactiae 2603V/R aldehyde dehydrogenase NP_688133.1 1130926 R 208435 CDS NP_688134.1 22537283 1013929 complement(1132376..1133383) 1 NC_004116.1 hypothetical protein 1133383 1013929 SAG1125 Streptococcus agalactiae 2603V/R hypothetical protein NP_688134.1 1132376 R 208435 CDS NP_688135.1 22537284 1013930 complement(1133491..1134177) 1 NC_004116.1 similar to OMNI:NTL01SPL0680; identified by sequence similarity; The product of this gene was detected by Western blot analysis. For details on the method see Tettelin et al. 2002.; hypothetical protein 1134177 1013930 SAG1126 Streptococcus agalactiae 2603V/R hypothetical protein NP_688135.1 1133491 R 208435 CDS NP_688136.1 22537285 1013931 1134596..1135936 1 NC_004116.1 similar to OMNI:NTL01SA1825; identified by sequence similarity; hypothetical protein 1135936 1013931 SAG1127 Streptococcus agalactiae 2603V/R hypothetical protein NP_688136.1 1134596 D 208435 CDS NP_688137.1 22537286 1013932 1136133..1136330 1 NC_004116.1 identified by match to PFAM protein family HMM PF01381; Cro/CI family transcriptional regulator 1136330 1013932 SAG1128 Streptococcus agalactiae 2603V/R Cro/CI family transcriptional regulator NP_688137.1 1136133 D 208435 CDS NP_688138.1 22537287 1013933 1136375..1136485 1 NC_004116.1 hypothetical protein 1136485 1013933 SAG1129 Streptococcus agalactiae 2603V/R hypothetical protein NP_688138.1 1136375 D 208435 CDS NP_688139.1 22537288 1013934 1136814..1136963 1 NC_004116.1 hypothetical protein 1136963 1013934 SAG1130 Streptococcus agalactiae 2603V/R hypothetical protein NP_688139.1 1136814 D 208435 CDS NP_688140.1 22537289 1013935 complement(1137039..1137533) 1 NC_004116.1 antioxidant activity; thioredoxin-dependent thiol peroxidase; forms homodimers in solution; shows substrate specificity to alkyl hydroperoxides; periplasmic protein; thiol peroxidase 1137533 tpx 1013935 tpx Streptococcus agalactiae 2603V/R thiol peroxidase NP_688140.1 1137039 R 208435 CDS NP_688141.1 22537290 1013936 complement(1137606..1138265) 1 NC_004116.1 hypothetical protein 1138265 1013936 SAG1132 Streptococcus agalactiae 2603V/R hypothetical protein NP_688141.1 1137606 R 208435 CDS NP_688142.1 22537291 1013937 complement(1138265..1139029) 1 NC_004116.1 hypothetical protein 1139029 1013937 SAG1133 Streptococcus agalactiae 2603V/R hypothetical protein NP_688142.1 1138265 R 208435 CDS NP_688143.1 22537292 1013938 complement(1139034..1139675) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00392; GntR family transcriptional regulator 1139675 1013938 SAG1134 Streptococcus agalactiae 2603V/R GntR family transcriptional regulator NP_688143.1 1139034 R 208435 CDS NP_688144.1 22537293 1013939 complement(1139839..1140390) 1 NC_004116.1 similar to OMNI:EF0080; identified by sequence similarity; gls24 protein 1140390 1013939 SAG1135 Streptococcus agalactiae 2603V/R gls24 protein NP_688144.1 1139839 R 208435 CDS NP_688145.1 22537294 1013940 complement(1140412..1140609) 1 NC_004116.1 hypothetical protein 1140609 1013940 SAG1136 Streptococcus agalactiae 2603V/R hypothetical protein NP_688145.1 1140412 R 208435 CDS NP_688146.1 22537295 1013941 complement(1140656..1141198) 1 NC_004116.1 similar to OMNI:EF0604; identified by sequence similarity; gls24 protein 1141198 1013941 SAG1137 Streptococcus agalactiae 2603V/R gls24 protein NP_688146.1 1140656 R 208435 CDS NP_688147.1 22537296 1013942 complement(1141254..1141448) 1 NC_004116.1 hypothetical protein 1141448 1013942 SAG1138 Streptococcus agalactiae 2603V/R hypothetical protein NP_688147.1 1141254 R 208435 CDS NP_688148.1 22537297 1013943 complement(1141458..1142039) 1 NC_004116.1 hypothetical protein 1142039 1013943 SAG1139 Streptococcus agalactiae 2603V/R hypothetical protein NP_688148.1 1141458 R 208435 CDS NP_688149.1 22537298 1013944 complement(1142054..1142302) 1 NC_004116.1 hypothetical protein 1142302 1013944 SAG1140 Streptococcus agalactiae 2603V/R hypothetical protein NP_688149.1 1142054 R 208435 CDS NP_688150.1 22537299 1013945 complement(1142350..1142688) 1 NC_004116.1 hypothetical protein 1142688 1013945 SAG1141 Streptococcus agalactiae 2603V/R hypothetical protein NP_688150.1 1142350 R 208435 CDS NP_688151.1 22537300 1013946 complement(1143007..1145286) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00580; ATP-dependent DNA helicase PcrA 1145286 pcrA 1013946 pcrA Streptococcus agalactiae 2603V/R ATP-dependent DNA helicase PcrA NP_688151.1 1143007 R 208435 CDS NP_688152.1 22537301 1013947 complement(1145392..1145778) 1 NC_004116.1 hypothetical protein 1145778 1013947 SAG1143 Streptococcus agalactiae 2603V/R hypothetical protein NP_688152.1 1145392 R 208435 CDS NP_688153.1 22537302 1013948 complement(1145911..1147236) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00860; uracil permease 1147236 uraA 1013948 uraA Streptococcus agalactiae 2603V/R uracil permease NP_688153.1 1145911 R 208435 CDS NP_688154.1 22537303 1013949 1147833..1149179 1 NC_004116.1 identified by match to PFAM protein family HMM PF01235; sodium:alanine symporter family protein 1149179 1013949 SAG1145 Streptococcus agalactiae 2603V/R sodium:alanine symporter family protein NP_688154.1 1147833 D 208435 CDS NP_688155.1 22537304 1013950 1149243..1150478 1 NC_004116.1 identified by match to PFAM protein family HMM PF01545; cation efflux family protein 1150478 1013950 SAG1146 Streptococcus agalactiae 2603V/R cation efflux family protein NP_688155.1 1149243 D 208435 CDS NP_688156.1 22537305 1013951 1150637..1151029 1 NC_004116.1 hypothetical protein 1151029 1013951 SAG1147 Streptococcus agalactiae 2603V/R hypothetical protein NP_688156.1 1150637 D 208435 CDS NP_688157.1 22537306 1013952 1151010..1151705 1 NC_004116.1 hypothetical protein 1151705 1013952 SAG1148 Streptococcus agalactiae 2603V/R hypothetical protein NP_688157.1 1151010 D 208435 CDS NP_688158.1 22537307 1013953 1151774..1152397 1 NC_004116.1 similar to OMNI:NTL01SPL1018; identified by sequence similarity; hypothetical protein 1152397 1013953 SAG1149 Streptococcus agalactiae 2603V/R hypothetical protein NP_688158.1 1151774 D 208435 CDS NP_688159.1 22537308 1013955 complement(1152810..1154012) 1 NC_004116.1 in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins; 30S ribosomal protein S1 1154012 rpsA 1013955 rpsA Streptococcus agalactiae 2603V/R 30S ribosomal protein S1 NP_688159.1 1152810 R 208435 CDS NP_688160.1 22537309 1013958 complement(1154356..1154586) 1 NC_004116.1 hypothetical protein 1154586 1013958 SAG1151 Streptococcus agalactiae 2603V/R hypothetical protein NP_688160.1 1154356 R 208435 CDS NP_688161.1 22537310 1013959 complement(1154670..1155692) 1 NC_004116.1 catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids; branched-chain amino acid aminotransferase 1155692 ilvE 1013959 ilvE Streptococcus agalactiae 2603V/R branched-chain amino acid aminotransferase NP_688161.1 1154670 R 208435 CDS NP_688162.1 22537311 1013960 complement(1155806..1158265) 1 NC_004116.1 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling; DNA topoisomerase IV subunit A 1158265 parC 1013960 parC Streptococcus agalactiae 2603V/R DNA topoisomerase IV subunit A NP_688162.1 1155806 R 208435 CDS NP_688163.1 22537312 1013961 complement(1158399..1160360) 1 NC_004116.1 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling; DNA topoisomerase IV subunit B 1160360 parE 1013961 parE Streptococcus agalactiae 2603V/R DNA topoisomerase IV subunit B NP_688163.1 1158399 R 208435 CDS NP_688164.1 22537313 1013962 1160462..1161100 1 NC_004116.1 involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsX; glycerol-3-phosphate acyltransferase PlsY 1161100 1013962 SAG1155 Streptococcus agalactiae 2603V/R glycerol-3-phosphate acyltransferase PlsY NP_688164.1 1160462 D 208435 CDS NP_688165.1 22537314 1013963 complement(1161166..1161819) 1 NC_004116.1 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine; uracil-DNA glycosylase 1161819 ung 1013963 ung Streptococcus agalactiae 2603V/R uracil-DNA glycosylase NP_688165.1 1161166 R 208435 CDS NP_688166.1 22537315 1013964 complement(1161918..1162403) 1 NC_004116.1 hypothetical protein 1162403 1013964 SAG1157 Streptococcus agalactiae 2603V/R hypothetical protein NP_688166.1 1161918 R 208435 CDS NP_688167.1 22537316 1013965 complement(1162517..1163758) 1 NC_004116.1 identified by match to PFAM protein family HMM PF02348; CMP-N-acetylneuraminic acid synthetase NeuA 1163758 neuA 1013965 neuA Streptococcus agalactiae 2603V/R CMP-N-acetylneuraminic acid synthetase NeuA NP_688167.1 1162517 R 208435 CDS NP_688168.1 22537317 1013966 complement(1163769..1164398) 1 NC_004116.1 neuD protein 1164398 neuD 1013966 neuD Streptococcus agalactiae 2603V/R neuD protein NP_688168.1 1163769 R 208435 CDS NP_688169.1 22537318 1013967 complement(1164395..1165549) 1 NC_004116.1 UDP-N-acetylglucosamine-2-epimerase NeuC 1165549 neuC 1013967 neuC Streptococcus agalactiae 2603V/R UDP-N-acetylglucosamine-2-epimerase NeuC NP_688169.1 1164395 R 208435 CDS NP_688170.1 22537319 1013968 complement(1165626..1166651) 1 NC_004116.1 identified by match to PFAM protein family HMM PF01354; N-acetyl neuramic acid synthetase NeuB 1166651 neuB 1013968 neuB Streptococcus agalactiae 2603V/R N-acetyl neuramic acid synthetase NeuB NP_688170.1 1165626 R 208435 CDS NP_688171.1 22537320 1013969 complement(1166651..1168051) 1 NC_004116.1 identified by match to PFAM protein family HMM PF01943; polysaccharide biosynthesis protein CpsL 1168051 cpsL 1013969 cpsL Streptococcus agalactiae 2603V/R polysaccharide biosynthesis protein CpsL NP_688171.1 1166651 R 208435 CDS NP_688172.1 22537321 1013970 complement(1168048..1169004) 1 NC_004116.1 similar to GP:13549137; identified by sequence similarity; polysaccharide biosynthesis protein CpsK(V) 1169004 cpsK 1013970 cpsK Streptococcus agalactiae 2603V/R polysaccharide biosynthesis protein CpsK(V) NP_688172.1 1168048 R 208435 CDS NP_688173.1 22537322 1013971 complement(1169001..1169966) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00535; glycosyl transferase CpsJ(V) 1169966 cpsJ 1013971 cpsJ Streptococcus agalactiae 2603V/R glycosyl transferase CpsJ(V) NP_688173.1 1169001 R 208435 CDS NP_688174.1 22537323 1013972 complement(1169959..1170942) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00535; glycosyl transferase CpsO(V) 1170942 cpsO 1013972 cpsO Streptococcus agalactiae 2603V/R glycosyl transferase CpsO(V) NP_688174.1 1169959 R 208435 CDS NP_688175.1 22537324 1013973 complement(1170946..1171833) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00535; glycosyl transferase CpsN(V) 1171833 cpsN 1013973 cpsN Streptococcus agalactiae 2603V/R glycosyl transferase CpsN(V) NP_688175.1 1170946 R 208435 CDS NP_688176.1 22537325 1013974 complement(1171859..1172584) 1 NC_004116.1 similar to GP:13549133; identified by sequence similarity; polysaccharide biosynthesis protein CpsM(V) 1172584 cpsM 1013974 cpsM Streptococcus agalactiae 2603V/R polysaccharide biosynthesis protein CpsM(V) NP_688176.1 1171859 R 208435 CDS NP_688177.1 22537326 1013975 complement(1172623..1173717) 1 NC_004116.1 similar to GP:13549132; identified by sequence similarity; polysaccharide biosynthesis protein cpsH(V) 1173717 cpsH 1013975 cpsH Streptococcus agalactiae 2603V/R polysaccharide biosynthesis protein cpsH(V) NP_688177.1 1172623 R 208435 CDS NP_688178.1 22537327 1013976 complement(1173704..1174195) 1 NC_004116.1 similar to GP:5823214; identified by sequence similarity; glycosyl transferase CpsG(V) 1174195 cpsG 1013976 cpsG Streptococcus agalactiae 2603V/R glycosyl transferase CpsG(V) NP_688178.1 1173704 R 208435 CDS NP_688179.1 22537328 1013977 complement(1174195..1174644) 1 NC_004116.1 similar to GP:13549130; identified by sequence similarity; polysaccharide biosynthesis protein CpsF 1174644 cpsF 1013977 cpsF Streptococcus agalactiae 2603V/R polysaccharide biosynthesis protein CpsF NP_688179.1 1174195 R 208435 CDS NP_688180.1 22537329 1013978 complement(1174668..1176056) 1 NC_004116.1 identified by match to PFAM protein family HMM PF02397; glycosyl transferase CpsE 1176056 cpsE 1013978 cpsE Streptococcus agalactiae 2603V/R glycosyl transferase CpsE NP_688180.1 1174668 R 208435 CDS NP_688181.1 22537330 1013979 complement(1176069..1176758) 1 NC_004116.1 identified by match to TIGR protein family HMM TIGR01007; cpsD protein 1176758 cpsD 1013979 cpsD Streptococcus agalactiae 2603V/R cpsD protein NP_688181.1 1176069 R 208435 CDS NP_688182.1 22537331 1013980 complement(1176769..1177461) 1 NC_004116.1 identified by match to PFAM protein family HMM PF02706; cpsC protein 1177461 cpsC 1013980 cpsC Streptococcus agalactiae 2603V/R cpsC protein NP_688182.1 1176769 R 208435 CDS NP_688183.1 22537332 1013981 complement(1177470..1178201) 1 NC_004116.1 identified by match to PFAM protein family HMM PF02811; capsular polysaccharide biosynthesis protein CpsB 1178201 cpsB 1013981 cpsB Streptococcus agalactiae 2603V/R capsular polysaccharide biosynthesis protein CpsB NP_688183.1 1177470 R 208435 CDS NP_688184.1 22537333 1013982 complement(1178207..1179664) 1 NC_004116.1 identified by match to TIGR protein family HMM TIGR00350; capsular polysaccharide biosynthesis protein CpsA 1179664 cpsA 1013982 cpsA Streptococcus agalactiae 2603V/R capsular polysaccharide biosynthesis protein CpsA NP_688184.1 1178207 R 208435 CDS NP_688185.1 22537334 1013983 1179904..1180776 1 NC_004116.1 identified by match to PFAM protein family HMM PF00126; LysR family transcriptional regulator 1180776 1013983 SAG1176 Streptococcus agalactiae 2603V/R LysR family transcriptional regulator NP_688185.1 1179904 D 208435 CDS NP_688186.1 22537335 1013984 complement(1180801..1181568) 1 NC_004116.1 hypothetical protein 1181568 1013984 SAG1177 Streptococcus agalactiae 2603V/R hypothetical protein NP_688186.1 1180801 R 208435 CDS NP_688187.1 22537336 1013985 complement(1181577..1182287) 1 NC_004116.1 catalyzes the reversible phosphorolysis of ribonucleosides and 2'- deoxyribonucleosides to the free base and (2'-deoxy)ribose-1- phosphate; purine nucleoside phosphorylase 1182287 deoD 1013985 deoD Streptococcus agalactiae 2603V/R purine nucleoside phosphorylase NP_688187.1 1181577 R 208435 CDS NP_688188.1 22537337 1013986 complement(1182271..1183527) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00654; voltage-gated chloride channel family protein 1183527 1013986 SAG1179 Streptococcus agalactiae 2603V/R voltage-gated chloride channel family protein NP_688188.1 1182271 R 208435 CDS NP_688189.1 22537338 1013987 complement(1183529..1184338) 1 NC_004116.1 catalyzes the formation of a purine and ribose phosphate from a purine nucleoside; in E. coli this enzyme functions in xanthosine degradation; purine nucleoside phosphorylase 1184338 deoD-2 1013987 deoD-2 Streptococcus agalactiae 2603V/R purine nucleoside phosphorylase NP_688189.1 1183529 R 208435 CDS NP_688190.1 22537339 1013988 complement(1184377..1184784) 1 NC_004116.1 arsenate reductase 1184784 arsC 1013988 arsC Streptococcus agalactiae 2603V/R arsenate reductase NP_688190.1 1184377 R 208435 CDS NP_688191.1 22537340 1013989 complement(1184835..1186046) 1 NC_004116.1 catalyzes the transfer of phosphate between the C1 and C5 carbons of pentose; phosphopentomutase 1186046 deoB-1 1013989 deoB-1 Streptococcus agalactiae 2603V/R phosphopentomutase NP_688191.1 1184835 R 208435 CDS NP_688192.1 22537341 1013990 complement(1186103..1186774) 1 NC_004116.1 Catalyzes D-ribose 5-phosphate --> D-ribulose 5-phosphate in the nonoxidative branch of the pentose phosphate pathway; ribose-5-phosphate isomerase A 1186774 rpiA 1013990 rpiA Streptococcus agalactiae 2603V/R ribose-5-phosphate isomerase A NP_688192.1 1186103 R 208435 CDS NP_688193.1 22537342 1013991 complement(1187012..1187722) 1 NC_004116.1 hypothetical protein 1187722 1013991 SAG1184 Streptococcus agalactiae 2603V/R hypothetical protein NP_688193.1 1187012 R 208435 CDS NP_688194.1 22537343 1013992 complement(1187812..1188600) 1 NC_004116.1 similar to GP:7453518; identified by sequence similarity; tributyrin esterase 1188600 estA 1013992 estA Streptococcus agalactiae 2603V/R tributyrin esterase NP_688194.1 1187812 R 208435 CDS NP_688195.1 22537344 1013993 complement(1188657..1190318) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00753; metallo-beta-lactamase superfamily protein 1190318 1013993 SAG1186 Streptococcus agalactiae 2603V/R metallo-beta-lactamase superfamily protein NP_688195.1 1188657 R 208435 CDS NP_688196.1 22537345 1013994 complement(1190614..1191375) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00005; ABC transporter ATP-binding protein 1191375 1013994 SAG1187 Streptococcus agalactiae 2603V/R ABC transporter ATP-binding protein NP_688196.1 1190614 R 208435 CDS NP_688197.1 22537346 1013995 complement(1191375..1192238) 1 NC_004116.1 ABC transporter permease 1192238 1013995 SAG1188 Streptococcus agalactiae 2603V/R ABC transporter permease NP_688197.1 1191375 R 208435 CDS NP_688198.1 22537347 1013996 complement(1192251..1193255) 1 NC_004116.1 hypothetical protein 1193255 1013996 SAG1189 Streptococcus agalactiae 2603V/R hypothetical protein NP_688198.1 1192251 R 208435 CDS NP_688199.1 22537348 1013997 1193614..1195269 1 NC_004116.1 similar to OMNI:SP0966; identified by sequence similarity; adherence and virulence protein A 1195269 pavA 1013997 pavA Streptococcus agalactiae 2603V/R adherence and virulence protein A NP_688199.1 1193614 D 208435 CDS NP_688200.1 22537349 1013998 complement(1195323..1196042) 1 NC_004116.1 identified by match to PFAM protein family HMM PF03306; alpha-acetolactate decarboxylase 1196042 budA 1013998 budA Streptococcus agalactiae 2603V/R alpha-acetolactate decarboxylase NP_688200.1 1195323 R 208435 CDS NP_688201.1 22537350 1013999 complement(1196056..1197738) 1 NC_004116.1 catalyzes the formation of 2-acetolactate from pyruvate in stationary phase; acetolactate synthase 1197738 ilvK 1013999 ilvK Streptococcus agalactiae 2603V/R acetolactate synthase NP_688201.1 1196056 R 208435 CDS NP_688202.1 22537351 1014000 complement(1197848..1199074) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00515; hypothetical protein 1199074 1014000 SAG1193 Streptococcus agalactiae 2603V/R hypothetical protein NP_688202.1 1197848 R 208435 CDS NP_688203.1 22537352 1014001 complement(1199064..1200254) 1 NC_004116.1 identified by match to PFAM protein family HMM PF01594; hypothetical protein 1200254 1014001 SAG1194 Streptococcus agalactiae 2603V/R hypothetical protein NP_688203.1 1199064 R 208435 CDS NP_688204.1 22537353 1014002 complement(1200346..1200807) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00293; MutT/nudix family protein 1200807 1014002 SAG1195 Streptococcus agalactiae 2603V/R MutT/nudix family protein NP_688204.1 1200346 R 208435 CDS NP_688205.1 22537354 1014003 complement(1200797..1201279) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00293; mutator MutT protein 1201279 mutX 1014003 mutX Streptococcus agalactiae 2603V/R mutator MutT protein NP_688205.1 1200797 R 208435 CDS NP_688206.1 22537355 1014004 1201497..1204715 1 NC_004116.1 identified by match to PFAM protein family HMM PF02278; hyaluronate lyase 1204715 1014004 SAG1197 Streptococcus agalactiae 2603V/R hyaluronate lyase NP_688206.1 1201497 D 208435 CDS NP_688207.1 22537356 1014005 complement(1204767..1205813) 1 NC_004116.1 identified by match to PFAM protein family HMM PF01370; dTDP-glucose 4,6-dehydratase 1205813 rfbB 1014005 rfbB Streptococcus agalactiae 2603V/R dTDP-glucose 4,6-dehydratase NP_688207.1 1204767 R 208435 CDS NP_688208.1 22537357 1014006 complement(1206020..1206613) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00908; dTDP-4-keto-6-deoxyglucose-3,5-epimerase 1206613 1014006 SAG1199 Streptococcus agalactiae 2603V/R dTDP-4-keto-6-deoxyglucose-3,5-epimerase NP_688208.1 1206020 R 208435 CDS NP_688209.1 22537358 1014007 complement(1206613..1207482) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00483; glucose-1-phosphate thymidylyltransferase 1207482 rfbA 1014007 rfbA Streptococcus agalactiae 2603V/R glucose-1-phosphate thymidylyltransferase NP_688209.1 1206613 R 208435 CDS NP_688210.1 22537359 1014008 complement(1207541..1208644) 1 NC_004116.1 identified by match to PFAM protein family HMM PF01266; iminodiacetate oxidase 1208644 1014008 SAG1201 Streptococcus agalactiae 2603V/R iminodiacetate oxidase NP_688210.1 1207541 R 208435 CDS NP_688211.1 22537360 1014009 complement(1208653..1209441) 1 NC_004116.1 hypothetical protein 1209441 1014009 SAG1202 Streptococcus agalactiae 2603V/R hypothetical protein NP_688211.1 1208653 R 208435 CDS NP_688212.1 22537361 1014010 complement(1209431..1210114) 1 NC_004116.1 hypothetical protein 1210114 1014010 SAG1203 Streptococcus agalactiae 2603V/R hypothetical protein NP_688212.1 1209431 R 208435 CDS NP_688213.1 22537362 1014011 complement(1210218..1210898) 1 NC_004116.1 identified by match to TIGR protein family HMM TIGR01446; DNA replication protein DnaD 1210898 1014011 SAG1204 Streptococcus agalactiae 2603V/R DNA replication protein DnaD NP_688213.1 1210218 R 208435 CDS NP_688214.1 22537363 1014012 complement(1211016..1211534) 1 NC_004116.1 catalyzes a salvage reaction resulting in the formation of AMP which is metabolically less costly than a de novo synthesis; adenine phosphoribosyltransferase 1211534 apt 1014012 apt Streptococcus agalactiae 2603V/R adenine phosphoribosyltransferase NP_688214.1 1211016 R 208435 CDS NP_688215.1 22537364 1014013 complement(1211657..1214221) 1 NC_004116.1 hypothetical protein 1214221 1014013 SAG1206 Streptococcus agalactiae 2603V/R hypothetical protein NP_688215.1 1211657 R 208435 CDS NP_688216.1 22537365 1014014 complement(1214205..1214303) 1 NC_004116.1 hypothetical protein 1214303 1014014 SAG1207 Streptococcus agalactiae 2603V/R hypothetical protein NP_688216.1 1214205 R 208435 CDS NP_688217.1 22537366 1014015 complement(1214373..1216571) 1 NC_004116.1 identified by match to PFAM protein family HMM PF01368; single-stranded-DNA-specific exonuclease RecJ 1216571 recJ 1014015 recJ Streptococcus agalactiae 2603V/R single-stranded-DNA-specific exonuclease RecJ NP_688217.1 1214373 R 208435 CDS NP_688218.1 22537367 1014016 complement(1216568..1217329) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00106; short chain dehydrogenase/reductase family oxidoreductase 1217329 1014016 SAG1209 Streptococcus agalactiae 2603V/R short chain dehydrogenase/reductase family oxidoreductase NP_688218.1 1216568 R 208435 CDS NP_688219.1 22537368 1014017 complement(1217331..1218260) 1 NC_004116.1 member of metallo-beta-lactamase family; the purified enzyme from Escherichia coli forms dimeric zinc phosphodiesterase; in Bacillus subtilis this protein is a 3'-tRNA processing endoribonuclease and is essential while in Escherichia coli it is not; associates with two zinc ions; ribonuclease Z 1218260 1014017 SAG1210 Streptococcus agalactiae 2603V/R ribonuclease Z NP_688219.1 1217331 R 208435 CDS NP_688220.1 22537369 1014018 complement(1218302..1218949) 1 NC_004116.1 hypothetical protein 1218949 1014018 SAG1211 Streptococcus agalactiae 2603V/R hypothetical protein NP_688220.1 1218302 R 208435 CDS NP_688221.1 22537370 1014019 complement(1218942..1220180) 1 NC_004116.1 identified by match to TIGR protein family HMM TIGR00231; GTP-binding protein HflX 1220180 hflX 1014019 hflX Streptococcus agalactiae 2603V/R GTP-binding protein HflX NP_688221.1 1218942 R 208435 CDS NP_688222.1 22537371 1014020 complement(1220271..1221161) 1 NC_004116.1 IPP transferase; isopentenyltransferase; involved in tRNA modification; in Escherichia coli this enzyme catalyzes the addition of a delta2-isopentenyl group from dimethylallyl diphosphate to the N6-nitrogen of adenosine adjacent to the anticodon of tRNA species that read codons starting with uracil; further tRNA modifications may occur; mutations in miaA result in defects in translation efficiency and fidelity; tRNA delta(2)-isopentenylpyrophosphate transferase 1221161 miaA 1014020 miaA Streptococcus agalactiae 2603V/R tRNA delta(2)-isopentenylpyrophosphate transferase NP_688222.1 1220271 R 208435 CDS NP_688223.1 22537372 1014021 1221272..1221448 1 NC_004116.1 hypothetical protein 1221448 1014021 SAG1214 Streptococcus agalactiae 2603V/R hypothetical protein NP_688223.1 1221272 D 208435 CDS NP_688224.1 22537373 1014022 complement(1221490..1222407) 1 NC_004116.1 similar to OMNI:SA1184; identified by sequence similarity; hypothetical protein 1222407 1014022 SAG1215 Streptococcus agalactiae 2603V/R hypothetical protein NP_688224.1 1221490 R 208435 CDS NP_688225.1 22537374 1014023 complement(1222542..1226300) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00128; pullulanase 1226300 1014023 SAG1216 Streptococcus agalactiae 2603V/R pullulanase NP_688225.1 1222542 R 208435 CDS NP_688226.1 22537375 1014025 complement(1227217..1227801) 1 NC_004116.1 hypothetical protein 1227801 1014025 SAG1218 Streptococcus agalactiae 2603V/R hypothetical protein NP_688226.1 1227217 R 208435 CDS NP_688227.1 22537376 1014026 complement(1227898..1229304) 1 NC_004116.1 divalent metal ion-dependent extracellular dipeptidase; able to hydrolyze a broad range of dipeptides but no tri-, tetra-, or larger oligopeptides; differences in the amino acid specificity of the cleavage site varies between species; similar to succinyl-diaminopimelate desuccinylases; dipeptidase PepV 1229304 1014026 SAG1219 Streptococcus agalactiae 2603V/R dipeptidase PepV NP_688227.1 1227898 R 208435 CDS NP_688228.1 22537377 1014027 complement(1229351..1229953) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00881; nitroreductase family protein 1229953 1014027 SAG1220 Streptococcus agalactiae 2603V/R nitroreductase family protein NP_688228.1 1229351 R 208435 CDS NP_688229.1 22537378 1014029 complement(1231946..1233727) 1 NC_004116.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision; excinuclease ABC subunit C 1233727 uvrC 1014029 uvrC Streptococcus agalactiae 2603V/R excinuclease ABC subunit C NP_688229.1 1231946 R 208435 CDS NP_688230.1 22537379 1014030 1233886..1234653 1 NC_004116.1 hypothetical protein 1234653 1014030 SAG1223 Streptococcus agalactiae 2603V/R hypothetical protein NP_688230.1 1233886 D 208435 CDS NP_688231.1 22537380 1014031 complement(1234712..1236052) 1 NC_004116.1 identified by match to PFAM protein family HMM PF01554; MATE efflux family protein 1236052 1014031 SAG1224 Streptococcus agalactiae 2603V/R MATE efflux family protein NP_688231.1 1234712 R 208435 CDS NP_688232.1 22537381 1014032 complement(1236152..1236562) 1 NC_004116.1 hypothetical protein 1236562 1014032 SAG1225 Streptococcus agalactiae 2603V/R hypothetical protein NP_688232.1 1236152 R 208435 CDS NP_688233.1 22537382 1014033 complement(1236572..1237069) 1 NC_004116.1 hypothetical protein 1237069 1014033 SAG1226 Streptococcus agalactiae 2603V/R hypothetical protein NP_688233.1 1236572 R 208435 CDS NP_688234.1 22537383 1014034 1237291..1237887 1 NC_004116.1 similar to GB:AL009126; identified by sequence similarity; The product of this gene was detected by Western blot analysis. For details on the method see Tettelin et al. 2002.; hypothetical protein 1237887 1014034 SAG1227 Streptococcus agalactiae 2603V/R hypothetical protein NP_688234.1 1237291 D 208435 CDS NP_688235.1 22537384 1014035 1238076..1238366 1 NC_004116.1 identified by match to PFAM protein family HMM PF01527; ISSdy1, transposase OrfA 1238366 1014035 SAG1228 Streptococcus agalactiae 2603V/R ISSdy1, transposase OrfA NP_688235.1 1238076 D 208435 CDS NP_688236.1 22537385 1014036 1238402..1239181 1 NC_004116.1 identified by match to PFAM protein family HMM PF00665; ISSdy1, transposase OrfB 1239181 1014036 SAG1229 Streptococcus agalactiae 2603V/R ISSdy1, transposase OrfB NP_688236.1 1238402 D 208435 CDS NP_688237.1 22537386 1014037 1239405..1239695 1 NC_004116.1 hypothetical protein 1239695 1014037 SAG1230 Streptococcus agalactiae 2603V/R hypothetical protein NP_688237.1 1239405 D 208435 CDS NP_688238.1 22537387 1014040 complement(1241015..1243483) 1 NC_004116.1 identified by match to TIGR protein family HMM TIGR01363; The product of this gene was detected by Western blot analysis. For details on the method see Tettelin et al. 2002.; streptococcal histidine triad family protein 1243483 1014040 SAG1233 Streptococcus agalactiae 2603V/R streptococcal histidine triad family protein NP_688238.1 1241015 R 208435 CDS NP_688239.1 22537388 1014041 complement(1243496..1244416) 1 NC_004116.1 identified by match to PFAM protein family HMM PF01297; laminin-binding surface protein 1244416 lmb 1014041 lmb Streptococcus agalactiae 2603V/R laminin-binding surface protein NP_688239.1 1243496 R 208435 CDS NP_688240.1 22537389 1014042 complement(1244650..1245927) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00078; GBSi1, group II intron, maturase 1245927 1014042 SAG1235 Streptococcus agalactiae 2603V/R GBSi1, group II intron, maturase NP_688240.1 1244650 R 208435 CDS NP_688241.1 22537390 1014044 complement(1250615..1251949) 1 NC_004116.1 hypothetical protein 1251949 1014044 SAG1237 Streptococcus agalactiae 2603V/R hypothetical protein NP_688241.1 1250615 R 208435 CDS NP_688242.1 22537391 1014045 complement(1252057..1252665) 1 NC_004116.1 hypothetical protein 1252665 1014045 SAG1238 Streptococcus agalactiae 2603V/R hypothetical protein NP_688242.1 1252057 R 208435 CDS NP_688243.1 22537392 1014046 complement(1252715..1252945) 1 NC_004116.1 hypothetical protein 1252945 1014046 SAG1239 Streptococcus agalactiae 2603V/R hypothetical protein NP_688243.1 1252715 R 208435 CDS NP_688244.1 22537393 1014048 1253409..1253684 1 NC_004116.1 identified by match to PFAM protein family HMM PF01527; IS3 family transposase OrfA 1253684 1014048 SAG1241 Streptococcus agalactiae 2603V/R IS3 family transposase OrfA NP_688244.1 1253409 D 208435 CDS NP_688245.1 22537394 1014050 1254003..1254293 1 NC_004116.1 identified by match to PFAM protein family HMM PF01527; ISSdy1, transposase OrfA 1254293 1014050 SAG1243 Streptococcus agalactiae 2603V/R ISSdy1, transposase OrfA NP_688245.1 1254003 D 208435 CDS NP_688246.1 22537395 1014051 1254329..1255108 1 NC_004116.1 identified by match to PFAM protein family HMM PF00665; ISSdy1, transposase OrfB 1255108 1014051 SAG1244 Streptococcus agalactiae 2603V/R ISSdy1, transposase OrfB NP_688246.1 1254329 D 208435 CDS NP_688247.1 22537396 1014052 complement(1255213..1255329) 1 NC_004116.1 hypothetical protein 1255329 1014052 SAG1245 Streptococcus agalactiae 2603V/R hypothetical protein NP_688247.1 1255213 R 208435 CDS NP_688248.1 22537397 1014053 1255316..1256485 1 NC_004116.1 hypothetical protein 1256485 1014053 SAG1246 Streptococcus agalactiae 2603V/R hypothetical protein NP_688248.1 1255316 D 208435 CDS NP_688249.1 22537398 1014054 complement(1256680..1257879) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00589; phage integrase family site specific recombinase 1257879 1014054 SAG1247 Streptococcus agalactiae 2603V/R phage integrase family site specific recombinase NP_688249.1 1256680 R 208435 CDS NP_688250.1 22537399 1014055 complement(1257902..1258129) 1 NC_004116.1 hypothetical protein 1258129 1014055 SAG1248 Streptococcus agalactiae 2603V/R hypothetical protein NP_688250.1 1257902 R 208435 CDS NP_688251.1 22537400 1014056 complement(1258408..1258632) 1 NC_004116.1 identified by match to PFAM protein family HMM PF01381; Cro/CI family transcriptional regulator 1258632 1014056 SAG1249 Streptococcus agalactiae 2603V/R Cro/CI family transcriptional regulator NP_688251.1 1258408 R 208435 CDS NP_688252.1 22537401 1014057 complement(1258813..1260678) 1 NC_004116.1 identified by match to PFAM protein family HMM PF03432; Tn5252, relaxase 1260678 1014057 SAG1250 Streptococcus agalactiae 2603V/R Tn5252, relaxase NP_688252.1 1258813 R 208435 CDS NP_688253.1 22537402 1014058 complement(1260665..1261030) 1 NC_004116.1 similar to OMNI:SP1055; identified by sequence similarity; Tn5252, ORF 9 protein 1261030 1014058 SAG1251 Streptococcus agalactiae 2603V/R Tn5252, ORF 9 protein NP_688253.1 1260665 R 208435 CDS NP_688254.1 22537403 1014059 complement(1261037..1261399) 1 NC_004116.1 similar to OMNI:SP1054; identified by sequence similarity; Tn5252, ORF 10 protein 1261399 1014059 SAG1252 Streptococcus agalactiae 2603V/R Tn5252, ORF 10 protein NP_688254.1 1261037 R 208435 CDS NP_688255.1 22537404 1014060 complement(1261820..1263127) 1 NC_004116.1 identified by match to PFAM protein family HMM PF01610; This gene is located in a transposable element that also encodes two genes for a mercuric resistance operon, and there are two copies of the transposable element in this strain.; ISL3 family transposase 1263127 1014060 SAG1253 Streptococcus agalactiae 2603V/R ISL3 family transposase NP_688255.1 1261820 R 208435 CDS NP_688256.1 22537405 1014061 complement(1263287..1264927) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00070; mercuric reductase 1264927 merA-1 1014061 merA-1 Streptococcus agalactiae 2603V/R mercuric reductase NP_688256.1 1263287 R 208435 CDS NP_688257.1 22537406 1014062 complement(1264956..1265348) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00376; mercuric resistance operon regulatory protein MerR 1265348 merR-1 1014062 merR-1 Streptococcus agalactiae 2603V/R mercuric resistance operon regulatory protein MerR NP_688257.1 1264956 R 208435 CDS NP_688258.1 22537407 1014064 complement(1266612..1268741) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00122; cation transporter E1-E2 family ATPase 1268741 1014064 SAG1257 Streptococcus agalactiae 2603V/R cation transporter E1-E2 family ATPase NP_688258.1 1266612 R 208435 CDS NP_688259.1 22537408 1014065 complement(1268734..1269102) 1 NC_004116.1 identified by match to PFAM protein family HMM PF01022; cadmium efflux system accessory protein 1269102 cadC 1014065 cadC Streptococcus agalactiae 2603V/R cadmium efflux system accessory protein NP_688259.1 1268734 R 208435 CDS NP_688260.1 22537409 1014066 1269305..1269604 1 NC_004116.1 hypothetical protein 1269604 1014066 SAG1259 Streptococcus agalactiae 2603V/R hypothetical protein NP_688260.1 1269305 D 208435 CDS NP_688261.1 22537410 1014067 complement(1269658..1270446) 1 NC_004116.1 hypothetical protein 1270446 1014067 SAG1260 Streptococcus agalactiae 2603V/R hypothetical protein NP_688261.1 1269658 R 208435 CDS NP_688262.1 22537411 1014068 1270455..1271051 1 NC_004116.1 hypothetical protein 1271051 1014068 SAG1261 Streptococcus agalactiae 2603V/R hypothetical protein NP_688262.1 1270455 D 208435 CDS NP_688263.1 22537412 1014069 complement(1271225..1273312) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00122; cation transporter E1-E2 family ATPase 1273312 1014069 SAG1262 Streptococcus agalactiae 2603V/R cation transporter E1-E2 family ATPase NP_688263.1 1271225 R 208435 CDS YP_008592387.1 545902393 17097510 complement(1273451..1273657) 1 NC_004116.1 hypothetical protein 1273657 17097510 SAG_RS02360 Streptococcus agalactiae 2603V/R hypothetical protein YP_008592387.1 1273451 R 208435 CDS NP_688264.1 22537413 1014071 complement(1274268..1274714) 1 NC_004116.1 similar to GP:9965434; identified by sequence similarity; transcriptional repressor CopY 1274714 1014071 SAG1264 Streptococcus agalactiae 2603V/R transcriptional repressor CopY NP_688264.1 1274268 R 208435 CDS NP_688265.1 22537414 1014072 complement(1275139..1275759) 1 NC_004116.1 cadmium resistance transporter 1275759 1014072 SAG1265 Streptococcus agalactiae 2603V/R cadmium resistance transporter NP_688265.1 1275139 R 208435 CDS NP_688266.1 22537415 1014073 1276299..1276757 1 NC_004116.1 hypothetical protein 1276757 1014073 SAG1266 Streptococcus agalactiae 2603V/R hypothetical protein NP_688266.1 1276299 D 208435 CDS NP_688267.1 22537416 1014074 1276791..1277117 1 NC_004116.1 hypothetical protein 1277117 1014074 SAG1267 Streptococcus agalactiae 2603V/R hypothetical protein NP_688267.1 1276791 D 208435 CDS NP_688268.1 22537417 1014075 1277301..1277993 1 NC_004116.1 identified by match to PFAM protein family HMM PF01381; repressor protein 1277993 1014075 SAG1268 Streptococcus agalactiae 2603V/R repressor protein NP_688268.1 1277301 D 208435 CDS NP_688269.1 22537418 1014076 1277996..1278130 1 NC_004116.1 hypothetical protein 1278130 1014076 SAG1269 Streptococcus agalactiae 2603V/R hypothetical protein NP_688269.1 1277996 D 208435 CDS NP_688270.1 22537419 1014077 1278136..1279551 1 NC_004116.1 identified by match to PFAM protein family HMM PF00817; ImpB/MucB/SamB family protein 1279551 1014077 SAG1270 Streptococcus agalactiae 2603V/R ImpB/MucB/SamB family protein NP_688270.1 1278136 D 208435 CDS NP_688271.1 22537420 1014078 1279548..1279898 1 NC_004116.1 hypothetical protein 1279898 1014078 SAG1271 Streptococcus agalactiae 2603V/R hypothetical protein NP_688271.1 1279548 D 208435 CDS NP_688272.1 22537421 1014079 1279885..1280193 1 NC_004116.1 hypothetical protein 1280193 1014079 SAG1272 Streptococcus agalactiae 2603V/R hypothetical protein NP_688272.1 1279885 D 208435 CDS NP_688273.1 22537422 1014080 complement(1280202..1280558) 1 NC_004116.1 hypothetical protein 1280558 1014080 SAG1273 Streptococcus agalactiae 2603V/R hypothetical protein NP_688273.1 1280202 R 208435 CDS NP_688274.1 22537423 1014081 complement(1280548..1280937) 1 NC_004116.1 hypothetical protein 1280937 1014081 SAG1274 Streptococcus agalactiae 2603V/R hypothetical protein NP_688274.1 1280548 R 208435 CDS NP_688275.1 22537424 1014082 complement(1280934..1281161) 1 NC_004116.1 hypothetical protein 1281161 1014082 SAG1275 Streptococcus agalactiae 2603V/R hypothetical protein NP_688275.1 1280934 R 208435 CDS NP_688276.1 22537425 1014083 complement(1281215..1282291) 1 NC_004116.1 hypothetical protein 1282291 1014083 SAG1276 Streptococcus agalactiae 2603V/R hypothetical protein NP_688276.1 1281215 R 208435 CDS NP_688277.1 22537426 1014084 complement(1282330..1282821) 1 NC_004116.1 hypothetical protein 1282821 1014084 SAG1277 Streptococcus agalactiae 2603V/R hypothetical protein NP_688277.1 1282330 R 208435 CDS NP_688278.1 22537427 1014085 complement(1283064..1283354) 1 NC_004116.1 hypothetical protein 1283354 1014085 SAG1278 Streptococcus agalactiae 2603V/R hypothetical protein NP_688278.1 1283064 R 208435 CDS NP_688279.1 22537428 1014086 complement(1283368..1283667) 1 NC_004116.1 similar to GP:2735477; identified by sequence similarity; hypothetical protein 1283667 1014086 SAG1279 Streptococcus agalactiae 2603V/R hypothetical protein NP_688279.1 1283368 R 208435 CDS NP_688280.1 22537429 1014087 complement(1283738..1290562) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00176; SNF2 family protein 1290562 1014087 SAG1280 Streptococcus agalactiae 2603V/R SNF2 family protein NP_688280.1 1283738 R 208435 CDS NP_688281.1 22537430 1014088 complement(1290611..1291162) 1 NC_004116.1 hypothetical protein 1291162 1014088 SAG1281 Streptococcus agalactiae 2603V/R hypothetical protein NP_688281.1 1290611 R 208435 CDS NP_688282.1 22537431 1014089 complement(1291146..1291337) 1 NC_004116.1 similar to OMNI:EF0591; identified by sequence similarity; calcium-binding protein 1291337 1014089 SAG1282 Streptococcus agalactiae 2603V/R calcium-binding protein NP_688282.1 1291146 R 208435 CDS NP_688283.1 22537432 1014090 complement(1291338..1296233) 1 NC_004116.1 identified by match to TIGR protein family HMM TIGR01167; The product of this gene was detected by Western blot analysis. For details on the method see Tettelin et al. 2002.; agglutinin receptor 1296233 ssp-5 1014090 ssp-5 Streptococcus agalactiae 2603V/R agglutinin receptor NP_688283.1 1291338 R 208435 CDS NP_688284.1 22537433 1014091 1296512..1297102 1 NC_004116.1 similar to PID:1039476; identified by sequence similarity; abortive infection protein AbiGI 1297102 abiGI 1014091 abiGI Streptococcus agalactiae 2603V/R abortive infection protein AbiGI NP_688284.1 1296512 D 208435 CDS NP_688285.1 22537434 1014092 1297099..1297944 1 NC_004116.1 similar to GP:12620628; identified by sequence similarity; abortive infection protein AbiGII 1297944 abiGII 1014092 abiGII Streptococcus agalactiae 2603V/R abortive infection protein AbiGII NP_688285.1 1297099 D 208435 CDS NP_688286.1 22537435 1014093 complement(1298030..1300831) 1 NC_004116.1 Tn5252, Orf28 1300831 1014093 SAG1286 Streptococcus agalactiae 2603V/R Tn5252, Orf28 NP_688286.1 1298030 R 208435 CDS NP_688287.1 22537436 1014094 complement(1300833..1303163) 1 NC_004116.1 The product of this gene was detected by Western blot analysis. For details on the method see Tettelin et al. 2002.; Tn5252, Orf26 1303163 1014094 SAG1287 Streptococcus agalactiae 2603V/R Tn5252, Orf26 NP_688287.1 1300833 R 208435 CDS NP_688288.1 22537437 1014096 complement(1303556..1304410) 1 NC_004116.1 similar to GP:11559691; identified by sequence similarity; Tn5252, Orf23 1304410 1014096 SAG1289 Streptococcus agalactiae 2603V/R Tn5252, Orf23 NP_688288.1 1303556 R 208435 CDS NP_688289.1 22537438 1014097 complement(1304429..1304671) 1 NC_004116.1 hypothetical protein 1304671 1014097 SAG1290 Streptococcus agalactiae 2603V/R hypothetical protein NP_688289.1 1304429 R 208435 CDS NP_688290.1 22537439 1014099 complement(1306506..1306994) 1 NC_004116.1 hypothetical protein 1306994 1014099 SAG1292 Streptococcus agalactiae 2603V/R hypothetical protein NP_688290.1 1306506 R 208435 CDS NP_688291.1 22537440 1014100 complement(1307071..1307655) 1 NC_004116.1 identified by match to PFAM protein family HMM PF02517; protease 1307655 1014100 SAG1293 Streptococcus agalactiae 2603V/R protease NP_688291.1 1307071 R 208435 CDS NP_688292.1 22537441 1014101 complement(1307658..1307891) 1 NC_004116.1 hypothetical protein 1307891 1014101 SAG1294 Streptococcus agalactiae 2603V/R hypothetical protein NP_688292.1 1307658 R 208435 CDS NP_688293.1 22537442 1014102 complement(1307900..1308283) 1 NC_004116.1 hypothetical protein 1308283 1014102 SAG1295 Streptococcus agalactiae 2603V/R hypothetical protein NP_688293.1 1307900 R 208435 CDS NP_688294.1 22537443 1014103 complement(1308294..1308722) 1 NC_004116.1 hypothetical protein 1308722 1014103 SAG1296 Streptococcus agalactiae 2603V/R hypothetical protein NP_688294.1 1308294 R 208435 CDS NP_688295.1 22537444 1014104 complement(1308706..1310061) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00145; C-5 cytosine-specific DNA methylase 1310061 1014104 SAG1297 Streptococcus agalactiae 2603V/R C-5 cytosine-specific DNA methylase NP_688295.1 1308706 R 208435 CDS NP_688296.1 22537445 1014105 complement(1310113..1310208) 1 NC_004116.1 hypothetical protein 1310208 1014105 SAG1298 Streptococcus agalactiae 2603V/R hypothetical protein NP_688296.1 1310113 R 208435 CDS NP_688297.1 22537446 1014106 complement(1310210..1311028) 1 NC_004116.1 hypothetical protein 1311028 1014106 SAG1299 Streptococcus agalactiae 2603V/R hypothetical protein NP_688297.1 1310210 R 208435 CDS NP_688298.1 22537447 1014107 complement(1311025..1311198) 1 NC_004116.1 hypothetical protein 1311198 1014107 SAG1300 Streptococcus agalactiae 2603V/R hypothetical protein NP_688298.1 1311025 R 208435 CDS NP_688299.1 22537448 1014108 complement(1311397..1311762) 1 NC_004116.1 present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulates GTPase activity of translation factors; 50S ribosomal protein L7/L12 1311762 rplL 1014108 rplL Streptococcus agalactiae 2603V/R 50S ribosomal protein L7/L12 NP_688299.1 1311397 R 208435 CDS NP_688300.1 22537449 1014109 complement(1311826..1312326) 1 NC_004116.1 binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit; 50S ribosomal protein L10 1312326 rplJ 1014109 rplJ Streptococcus agalactiae 2603V/R 50S ribosomal protein L10 NP_688300.1 1311826 R 208435 CDS NP_688301.1 22537450 1014110 1312759..1314867 1 NC_004116.1 identified by match to PFAM protein family HMM PF00004; ATP-dependent Clp protease, ATP-binding subunit 1314867 1014110 SAG1303 Streptococcus agalactiae 2603V/R ATP-dependent Clp protease, ATP-binding subunit NP_688301.1 1312759 D 208435 CDS NP_688302.1 22537451 1014111 complement(1314851..1314949) 1 NC_004116.1 hypothetical protein 1314949 1014111 SAG1304 Streptococcus agalactiae 2603V/R hypothetical protein NP_688302.1 1314851 R 208435 CDS NP_688303.1 22537452 1014112 complement(1314960..1315904) 1 NC_004116.1 converts homocysteine and S-adenosyl-methionine to methionine and S-adenosyl-homocysteine or S-methyl-methionine and homocysteine to two methionines; homocysteine methyltransferase 1315904 mmuM 1014112 mmuM Streptococcus agalactiae 2603V/R homocysteine methyltransferase NP_688303.1 1314960 R 208435 CDS NP_688304.1 22537453 1014113 complement(1315909..1317285) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00324; amino acid permease 1317285 1014113 SAG1306 Streptococcus agalactiae 2603V/R amino acid permease NP_688304.1 1315909 R 208435 CDS NP_688305.1 22537454 1014114 complement(1317415..1318065) 1 NC_004116.1 hypothetical protein 1318065 1014114 SAG1307 Streptococcus agalactiae 2603V/R hypothetical protein NP_688305.1 1317415 R 208435 CDS NP_688306.1 22537455 1014115 complement(1318223..1318726) 1 NC_004116.1 hypothetical protein 1318726 1014115 SAG1308 Streptococcus agalactiae 2603V/R hypothetical protein NP_688306.1 1318223 R 208435 CDS NP_688307.1 22537456 1014116 complement(1318723..1318815) 1 NC_004116.1 hypothetical protein 1318815 1014116 SAG1309 Streptococcus agalactiae 2603V/R hypothetical protein NP_688307.1 1318723 R 208435 CDS NP_688308.1 22537457 1014117 1318818..1319366 1 NC_004116.1 identified by match to PFAM protein family HMM PF00440; TetR family transcriptional regulator 1319366 1014117 SAG1310 Streptococcus agalactiae 2603V/R TetR family transcriptional regulator NP_688308.1 1318818 D 208435 CDS NP_688309.1 22537458 1014118 complement(1319428..1320024) 1 NC_004116.1 binds guanine nucleotides; in Escherichia coli depletion results in defective cell division and filamentation; in Bacillus subtilis this gene is essential; ribosome biogenesis GTP-binding protein YsxC 1320024 engB 1014118 engB Streptococcus agalactiae 2603V/R ribosome biogenesis GTP-binding protein YsxC NP_688309.1 1319428 R 208435 CDS NP_688310.1 22537459 1014119 complement(1320035..1321261) 1 NC_004116.1 binds and unfolds substrates as part of the ClpXP protease; ATP-dependent protease ATP-binding subunit ClpX 1321261 clpX 1014119 clpX Streptococcus agalactiae 2603V/R ATP-dependent protease ATP-binding subunit ClpX NP_688310.1 1320035 R 208435 CDS NP_688311.1 22537460 1014120 complement(1321291..1321461) 1 NC_004116.1 hypothetical protein 1321461 1014120 SAG1313 Streptococcus agalactiae 2603V/R hypothetical protein NP_688311.1 1321291 R 208435 CDS NP_688312.1 22537461 1014121 complement(1321479..1321973) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00186; dihydrofolate reductase 1321973 folA 1014121 folA Streptococcus agalactiae 2603V/R dihydrofolate reductase NP_688312.1 1321479 R 208435 CDS NP_688313.1 22537462 1014122 complement(1322053..1322892) 1 NC_004116.1 ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived; thymidylate synthase 1322892 thyA 1014122 thyA Streptococcus agalactiae 2603V/R thymidylate synthase NP_688313.1 1322053 R 208435 CDS NP_688314.1 22537463 1014123 1323046..1324218 1 NC_004116.1 identified by match to PFAM protein family HMM PF01154; HMG-CoA synthase 1324218 1014123 SAG1316 Streptococcus agalactiae 2603V/R HMG-CoA synthase NP_688314.1 1323046 D 208435 CDS NP_688315.1 22537464 1014124 1324220..1325503 1 NC_004116.1 identified by match to PFAM protein family HMM PF00368; 3-hydroxy-3-methylglutaryl-CoA reductase 1325503 1014124 SAG1317 Streptococcus agalactiae 2603V/R 3-hydroxy-3-methylglutaryl-CoA reductase NP_688315.1 1324220 D 208435 CDS NP_688316.1 22537465 1014125 1325595..1326044 1 NC_004116.1 hypothetical protein 1326044 1014125 SAG1318 Streptococcus agalactiae 2603V/R hypothetical protein NP_688316.1 1325595 D 208435 CDS NP_688317.1 22537466 1014126 1326049..1326693 1 NC_004116.1 identified by match to PFAM protein family HMM PF03006; hemolysin III 1326693 1014126 SAG1319 Streptococcus agalactiae 2603V/R hemolysin III NP_688317.1 1326049 D 208435 CDS NP_688318.1 22537467 1014127 1326780..1327694 1 NC_004116.1 hypothetical protein 1327694 1014127 SAG1320 Streptococcus agalactiae 2603V/R hypothetical protein NP_688318.1 1326780 D 208435 CDS NP_688319.1 22537468 1014128 1327795..1328649 1 NC_004116.1 hypothetical protein 1328649 1014128 SAG1321 Streptococcus agalactiae 2603V/R hypothetical protein NP_688319.1 1327795 D 208435 CDS NP_688320.1 22537469 1014129 complement(1328695..1328913) 1 NC_004116.1 similar to OMNI:SP1775; identified by sequence similarity; hypothetical protein 1328913 1014129 SAG1322 Streptococcus agalactiae 2603V/R hypothetical protein NP_688320.1 1328695 R 208435 CDS NP_688321.1 22537470 1014130 complement(1328981..1329976) 1 NC_004116.1 catalyzes the isomerization of isopentenyl pyrophosphate to dimethylallyl diphosphate; isopentenyl pyrophosphate isomerase 1329976 1014130 SAG1323 Streptococcus agalactiae 2603V/R isopentenyl pyrophosphate isomerase NP_688321.1 1328981 R 208435 CDS NP_688322.1 22537471 1014131 complement(1329973..1330965) 1 NC_004116.1 identified by match to TIGR protein family HMM TIGR01220; phosphomevalonate kinase 1330965 1014131 SAG1324 Streptococcus agalactiae 2603V/R phosphomevalonate kinase NP_688322.1 1329973 R 208435 CDS NP_688323.1 22537472 1014132 complement(1330958..1331902) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00288; diphosphomevalonate decarboxylase 1331902 mvaD 1014132 mvaD Streptococcus agalactiae 2603V/R diphosphomevalonate decarboxylase NP_688323.1 1330958 R 208435 CDS NP_688324.1 22537473 1014133 complement(1331884..1332762) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00288; mevalonate kinase 1332762 1014133 SAG1326 Streptococcus agalactiae 2603V/R mevalonate kinase NP_688324.1 1331884 R 208435 CDS NP_688325.1 22537474 1014134 complement(1332878..1334107) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00512; sensor histidine kinase 1334107 1014134 SAG1327 Streptococcus agalactiae 2603V/R sensor histidine kinase NP_688325.1 1332878 R 208435 CDS NP_688326.1 22537475 1014135 complement(1334107..1334793) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00072; DNA-binding response regulator 1334793 1014135 SAG1328 Streptococcus agalactiae 2603V/R DNA-binding response regulator NP_688326.1 1334107 R 208435 CDS NP_688327.1 22537476 1014136 complement(1334795..1335421) 1 NC_004116.1 similar to OMNI:NTL01SPL0666; identified by sequence similarity; GTP pyrophosphokinase 1335421 1014136 SAG1329 Streptococcus agalactiae 2603V/R GTP pyrophosphokinase NP_688327.1 1334795 R 208435 CDS NP_688328.1 22537477 1014137 complement(1335570..1335776) 1 NC_004116.1 hypothetical protein 1335776 1014137 SAG1330 Streptococcus agalactiae 2603V/R hypothetical protein NP_688328.1 1335570 R 208435 CDS NP_688329.1 22537478 1014138 complement(1336428..1339367) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00746; hypothetical protein 1339367 1014138 SAG1331 Streptococcus agalactiae 2603V/R hypothetical protein NP_688329.1 1336428 R 208435 CDS NP_688330.1 22537479 1014139 complement(1340126..1340566) 1 NC_004116.1 identified by match to PFAM protein family HMM PF01047; MarR family transcriptional regulator 1340566 1014139 SAG1332 Streptococcus agalactiae 2603V/R MarR family transcriptional regulator NP_688330.1 1340126 R 208435 CDS NP_688331.1 22537480 1014140 1340840..1342912 1 NC_004116.1 identified by match to PFAM protein family HMM PF00149; 5'-nucleotidase 1342912 1014140 SAG1333 Streptococcus agalactiae 2603V/R 5'-nucleotidase NP_688331.1 1340840 D 208435 CDS NP_688332.1 22537481 1014141 complement(1342949..1343359) 1 NC_004116.1 cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+); peptide deformylase 1343359 1014141 SAG1334 Streptococcus agalactiae 2603V/R peptide deformylase NP_688332.1 1342949 R 208435 CDS NP_688333.1 22537482 1014142 complement(1343429..1344778) 1 NC_004116.1 converts 2-oxoglutarate to glutamate; in Escherichia coli this enzyme plays a role in glutamate synthesis when the cell is under energy restriction; uses NADPH; forms a homohexamer; glutamate dehydrogenase 1344778 gdhA 1014142 gdhA Streptococcus agalactiae 2603V/R glutamate dehydrogenase NP_688333.1 1343429 R 208435 CDS NP_688334.1 22537483 1014143 1344946..1345455 1 NC_004116.1 identified by sequence similarity; hypothetical protein 1345455 1014143 SAG1336 Streptococcus agalactiae 2603V/R hypothetical protein NP_688334.1 1344946 D 208435 CDS NP_688335.1 22537484 1014144 complement(1345496..1347265) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00005; ABC transporter ATP-binding protein/permease 1347265 1014144 SAG1337 Streptococcus agalactiae 2603V/R ABC transporter ATP-binding protein/permease NP_688335.1 1345496 R 208435 CDS NP_688336.1 22537485 1014145 complement(1347270..1349009) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00005; ABC transporter ATP-binding protein/permease 1349009 1014145 SAG1338 Streptococcus agalactiae 2603V/R ABC transporter ATP-binding protein/permease NP_688336.1 1347270 R 208435 CDS NP_688337.1 22537486 1014146 complement(1349076..1349549) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00583; acetyltransferase 1349549 1014146 SAG1339 Streptococcus agalactiae 2603V/R acetyltransferase NP_688337.1 1349076 R 208435 CDS NP_688338.1 22537487 1014147 complement(1349546..1351414) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00005; ABC transporter ATP-binding protein 1351414 1014147 SAG1340 Streptococcus agalactiae 2603V/R ABC transporter ATP-binding protein NP_688338.1 1349546 R 208435 CDS NP_688339.1 22537488 1014148 complement(1351425..1352633) 1 NC_004116.1 catalyzes the addition and repair of the 3'-terminal CCA sequence in tRNA; these proteins belong to the CCA-adding enzyme subfamily 2 which does not have phosphohydrolase activity; tRNA CCA-pyrophosphorylase 1352633 1014148 SAG1341 Streptococcus agalactiae 2603V/R tRNA CCA-pyrophosphorylase NP_688339.1 1351425 R 208435 CDS NP_688340.1 22537489 1014149 complement(1352818..1353666) 1 NC_004116.1 identified by match to PFAM protein family HMM PF02645; DegV family protein 1353666 1014149 SAG1342 Streptococcus agalactiae 2603V/R DegV family protein NP_688340.1 1352818 R 208435 CDS NP_688341.1 22537490 1014150 complement(1353666..1354046) 1 NC_004116.1 similar to OMNI:NTL01SPL0660; identified by sequence similarity; The product of this gene was detected by Western blot analysis. For details on the method see Tettelin et al. 2002.; hypothetical protein 1354046 1014150 SAG1343 Streptococcus agalactiae 2603V/R hypothetical protein NP_688341.1 1353666 R 208435 CDS NP_688342.1 22537491 1014151 complement(1354118..1354651) 1 NC_004116.1 hypothetical protein 1354651 1014151 SAG1344 Streptococcus agalactiae 2603V/R hypothetical protein NP_688342.1 1354118 R 208435 CDS NP_688343.1 22537492 1014152 complement(1354702..1355196) 1 NC_004116.1 hypothetical protein 1355196 1014152 SAG1345 Streptococcus agalactiae 2603V/R hypothetical protein NP_688343.1 1354702 R 208435 CDS NP_688344.1 22537493 1014153 complement(1355385..1357349) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00359; PTS system fructose specific transporter subunit IIABC 1357349 1014153 SAG1346 Streptococcus agalactiae 2603V/R PTS system fructose specific transporter subunit IIABC NP_688344.1 1355385 R 208435 CDS NP_688345.1 22537494 1014154 complement(1357346..1358257) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00294; 1-phosphofructokinase 1358257 fruK 1014154 fruK Streptococcus agalactiae 2603V/R 1-phosphofructokinase NP_688345.1 1357346 R 208435 CDS NP_688346.1 22537495 1014155 complement(1358254..1358997) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00455; lactose phosphotransferase system repressor 1358997 lacR-1 1014155 lacR-1 Streptococcus agalactiae 2603V/R lactose phosphotransferase system repressor NP_688346.1 1358254 R 208435 CDS NP_688347.1 22537496 1014156 complement(1359128..1360363) 1 NC_004116.1 identified by match to PFAM protein family HMM PF02388; beta-lactam resistance factor 1360363 1014156 SAG1349 Streptococcus agalactiae 2603V/R beta-lactam resistance factor NP_688347.1 1359128 R 208435 CDS NP_688348.1 22537497 1014157 complement(1360507..1362141) 1 NC_004116.1 identified by match to TIGR protein family HMM TIGR01168; surface antigen-like protein 1362141 1014157 SAG1350 Streptococcus agalactiae 2603V/R surface antigen-like protein NP_688348.1 1360507 R 208435 CDS NP_688349.1 22537498 1014158 complement(1362353..1363276) 1 NC_004116.1 ketopantoate reductase; catalyzes the NADPH reduction of ketopantoate to pantoate; functions in pantothenate (vitamin B5) biosynthesis; 2-dehydropantoate 2-reductase 1363276 1014158 SAG1351 Streptococcus agalactiae 2603V/R 2-dehydropantoate 2-reductase NP_688349.1 1362353 R 208435 CDS NP_688350.1 22537499 1014159 complement(1363289..1364359) 1 NC_004116.1 similar to OMNI:NTL01SPL0650; identified by sequence similarity; hypothetical protein 1364359 1014159 SAG1352 Streptococcus agalactiae 2603V/R hypothetical protein NP_688350.1 1363289 R 208435 CDS NP_688351.1 22537500 1014160 complement(1364496..1365488) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00070; pyridine nucleotide-disulfide oxidoreductase family protein 1365488 1014160 SAG1353 Streptococcus agalactiae 2603V/R pyridine nucleotide-disulfide oxidoreductase family protein NP_688351.1 1364496 R 208435 CDS NP_688352.1 22537501 1014161 complement(1365469..1366224) 1 NC_004116.1 methylates guanosine-37 in various tRNAs; uses S-adenosyl-L-methionine to transfer methyl group to tRNA; tRNA (guanine-N(1)-)-methyltransferase 1366224 trmD 1014161 trmD Streptococcus agalactiae 2603V/R tRNA (guanine-N(1)-)-methyltransferase NP_688352.1 1365469 R 208435 CDS NP_688353.1 22537502 1014162 complement(1366211..1366729) 1 NC_004116.1 Essential for efficient processing of 16S rRNA; 16S rRNA-processing protein RimM 1366729 rimM 1014162 rimM Streptococcus agalactiae 2603V/R 16S rRNA-processing protein RimM NP_688353.1 1366211 R 208435 CDS NP_688354.1 22537503 1014165 complement(1367051..1368562) 1 NC_004116.1 similar to GB:U01312 PID:460083; identified by sequence similarity; RofA family transcriptional regulator 1368562 1014165 SAG1356 Streptococcus agalactiae 2603V/R RofA family transcriptional regulator NP_688354.1 1367051 R 208435 CDS NP_688355.1 22537504 1014166 complement(1368694..1368936) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00013; KH domain-containing protein 1368936 1014166 SAG1357 Streptococcus agalactiae 2603V/R KH domain-containing protein NP_688355.1 1368694 R 208435 CDS NP_688356.1 22537505 1014167 complement(1368946..1369218) 1 NC_004116.1 binds to lower part of 30S body where it stabilizes two domains; required for efficient assembly of 30S; in Escherichia coli this protein has nuclease activity; 30S ribosomal protein S16 1369218 rpsP 1014167 rpsP Streptococcus agalactiae 2603V/R 30S ribosomal protein S16 NP_688356.1 1368946 R 208435 CDS NP_688357.1 22537506 1014168 complement(1369347..1370594) 1 NC_004116.1 identified by match to PFAM protein family HMM PF02687; permease 1370594 1014168 SAG1359 Streptococcus agalactiae 2603V/R permease NP_688357.1 1369347 R 208435 CDS NP_688358.1 22537507 1014169 complement(1370609..1371319) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00005; ABC transporter ATP-binding protein 1371319 1014169 SAG1360 Streptococcus agalactiae 2603V/R ABC transporter ATP-binding protein NP_688358.1 1370609 R 208435 CDS NP_688359.1 22537508 1014170 complement(1371322..1372566) 1 NC_004116.1 hypothetical protein 1372566 1014170 SAG1361 Streptococcus agalactiae 2603V/R hypothetical protein NP_688359.1 1371322 R 208435 CDS NP_688360.1 22537509 1014171 complement(1372768..1374366) 1 NC_004116.1 identified by match to PFAM protein family HMM PF02787; carbamoyl-phosphate synthase large subunit 1374366 1014171 SAG1362 Streptococcus agalactiae 2603V/R carbamoyl-phosphate synthase large subunit NP_688360.1 1372768 R 208435 CDS NP_688361.1 22537510 1014172 complement(1374422..1375492) 1 NC_004116.1 catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers; carbamoyl phosphate synthase small subunit 1375492 carA-2 1014172 carA-2 Streptococcus agalactiae 2603V/R carbamoyl phosphate synthase small subunit NP_688361.1 1374422 R 208435 CDS NP_688362.1 22537511 1014173 complement(1375541..1376062) 1 NC_004116.1 regulates pyrimidine biosynthesis by binding to the mRNA of the pyr genes, also has been shown to have uracil phosphoribosyltransferase activity; bifunctional pyrimidine regulatory protein PyrR/uracil phosphoribosyltransferase 1376062 pyrR 1014173 pyrR Streptococcus agalactiae 2603V/R bifunctional pyrimidine regulatory protein PyrR/uracil phosphoribosyltransferase NP_688362.1 1375541 R 208435 CDS NP_688363.1 22537512 1014174 complement(1376238..1377128) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00849; ribosomal large subunit pseudouridine synthase D 1377128 1014174 SAG1365 Streptococcus agalactiae 2603V/R ribosomal large subunit pseudouridine synthase D NP_688363.1 1376238 R 208435 CDS NP_688364.1 22537513 1014175 complement(1377112..1377576) 1 NC_004116.1 lipoprotein signal peptidase; integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis; lipoprotein signal peptidase 1377576 lspA 1014175 lspA Streptococcus agalactiae 2603V/R lipoprotein signal peptidase NP_688364.1 1377112 R 208435 CDS NP_688365.1 22537514 1014176 complement(1377585..1378490) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00126; LysR family transcriptional regulator 1378490 1014176 SAG1367 Streptococcus agalactiae 2603V/R LysR family transcriptional regulator NP_688365.1 1377585 R 208435 CDS NP_688366.1 22537515 1014177 complement(1378706..1378990) 1 NC_004116.1 involved in the peptidyltransferase reaction during translation; 50S ribosomal protein L27 1378990 rpmA 1014177 rpmA Streptococcus agalactiae 2603V/R 50S ribosomal protein L27 NP_688366.1 1378706 R 208435 CDS NP_688367.1 22537516 1014178 complement(1379021..1379359) 1 NC_004116.1 hypothetical protein 1379359 1014178 SAG1369 Streptococcus agalactiae 2603V/R hypothetical protein NP_688367.1 1379021 R 208435 CDS NP_688368.1 22537517 1014179 complement(1379366..1379680) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00829; 50S ribosomal protein L21 1379680 rplU 1014179 rplU Streptococcus agalactiae 2603V/R 50S ribosomal protein L21 NP_688368.1 1379366 R 208435 CDS NP_688369.1 22537518 1014180 complement(1379870..1381048) 1 NC_004116.1 hypothetical protein 1381048 1014180 SAG1371 Streptococcus agalactiae 2603V/R hypothetical protein NP_688369.1 1379870 R 208435 CDS NP_688370.1 22537519 1014181 complement(1381150..1382364) 1 NC_004116.1 Required for the synthesis of the thiazole moiety; thiamine biosynthesis protein ThiI 1382364 thiI 1014181 thiI Streptococcus agalactiae 2603V/R thiamine biosynthesis protein ThiI NP_688370.1 1381150 R 208435 CDS NP_688371.1 22537520 1014182 complement(1382366..1383511) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00266; cysteine desulfurase 1383511 iscS-2 1014182 iscS-2 Streptococcus agalactiae 2603V/R cysteine desulfurase NP_688371.1 1382366 R 208435 CDS NP_688372.1 22537521 1014183 1383758..1384210 1 NC_004116.1 hypothetical protein 1384210 1014183 SAG1374 Streptococcus agalactiae 2603V/R hypothetical protein NP_688372.1 1383758 D 208435 CDS NP_688373.1 22537522 1014184 complement(1384253..1385602) 1 NC_004116.1 catalyzes the reduction of 2 glutathione to glutathione disulfide; maintains high levels of reduced glutathione in the cytosol; involved in redox regulation and oxidative defense; glutathione reductase 1385602 gor 1014184 gor Streptococcus agalactiae 2603V/R glutathione reductase NP_688373.1 1384253 R 208435 CDS NP_688374.1 22537523 1014185 complement(1385777..1386112) 1 NC_004116.1 hypothetical protein 1386112 1014185 SAG1376 Streptococcus agalactiae 2603V/R hypothetical protein NP_688374.1 1385777 R 208435 CDS NP_688375.1 22537524 1014186 complement(1386196..1387362) 1 NC_004116.1 catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis; chorismate synthase 1387362 aroC 1014186 aroC Streptococcus agalactiae 2603V/R chorismate synthase NP_688375.1 1386196 R 208435 CDS NP_688376.1 22537525 1014187 complement(1387363..1388430) 1 NC_004116.1 catalyzes the formation of 3-dehydroquinate from 3-deoxy-arabino-heptulonate 7-phosphate; functions in aromatic amino acid biosynthesis; 3-dehydroquinate synthase 1388430 aroB 1014187 aroB Streptococcus agalactiae 2603V/R 3-dehydroquinate synthase NP_688376.1 1387363 R 208435 CDS NP_688377.1 22537526 1014188 complement(1388524..1389201) 1 NC_004116.1 catalyzes the dehydration of 3-dehydroquinate to form 3-dehydroshikimate in aromatic amino acid biosynthesis; 3-dehydroquinate dehydratase 1389201 aroD 1014188 aroD Streptococcus agalactiae 2603V/R 3-dehydroquinate dehydratase NP_688377.1 1388524 R 208435 CDS NP_688378.1 22537527 1014189 complement(1389201..1390358) 1 NC_004116.1 hypothetical protein 1390358 1014189 SAG1380 Streptococcus agalactiae 2603V/R hypothetical protein NP_688378.1 1389201 R 208435 CDS NP_688379.1 22537528 1014190 1390493..1392637 1 NC_004116.1 identified by match to PFAM protein family HMM PF00884; sulfatase 1392637 1014190 SAG1381 Streptococcus agalactiae 2603V/R sulfatase NP_688379.1 1390493 D 208435 CDS NP_688380.1 22537529 1014191 complement(1392879..1393238) 1 NC_004116.1 binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit; 50S ribosomal protein L20 1393238 rplT 1014191 rplT Streptococcus agalactiae 2603V/R 50S ribosomal protein L20 NP_688380.1 1392879 R 208435 CDS NP_688381.1 22537530 1014192 complement(1393296..1393496) 1 NC_004116.1 identified by match to PFAM protein family HMM PF01632; 50S ribosomal protein L35 1393496 rpmI 1014192 rpmI Streptococcus agalactiae 2603V/R 50S ribosomal protein L35 NP_688381.1 1393296 R 208435 CDS NP_688382.1 22537531 1014193 complement(1393536..1394066) 1 NC_004116.1 IF-3 has several functions that are required and promote translation initiation including; preventing association of 70S by binding to 30S; monitoring codon-anticodon interactions by promoting disassociation of fMet-tRNA(fMet) from initiation complexes formed on leaderless mRNAs or incorrectly bound noninitiatior tRNAs and complexes with noncanonical start sites; stimulates codon-anticodon interactions at P-site; involved in moving mRNA to the P-site; and in recycling subunits; translation initiation factor IF-3 1394066 infC 1014193 infC Streptococcus agalactiae 2603V/R translation initiation factor IF-3 NP_688382.1 1393536 R 208435 CDS NP_688383.1 22537532 1014194 complement(1394227..1394910) 1 NC_004116.1 Catalyzes the formation of (d)CDP from ATP and (d)CMP; cytidylate kinase 1394910 cmk 1014194 cmk Streptococcus agalactiae 2603V/R cytidylate kinase NP_688383.1 1394227 R 208435 CDS NP_688384.1 22537533 1014195 complement(1394921..1395445) 1 NC_004116.1 hypothetical protein 1395445 1014195 SAG1386 Streptococcus agalactiae 2603V/R hypothetical protein NP_688384.1 1394921 R 208435 CDS NP_688385.1 22537534 1014196 1395491..1395688 1 NC_004116.1 ferredoxin, 4Fe-4S 1395688 1014196 SAG1387 Streptococcus agalactiae 2603V/R ferredoxin, 4Fe-4S NP_688385.1 1395491 D 208435 CDS NP_688386.1 22537535 1014197 complement(1395675..1396166) 1 NC_004116.1 hypothetical protein 1396166 1014197 SAG1388 Streptococcus agalactiae 2603V/R hypothetical protein NP_688386.1 1395675 R 208435 CDS NP_688387.1 22537536 1014198 complement(1396195..1397415) 1 NC_004116.1 catalyzes the release of the N-terminal amino acid from a tripeptide; peptidase T 1397415 pepT 1014198 pepT Streptococcus agalactiae 2603V/R peptidase T NP_688387.1 1396195 R 208435 CDS NP_688388.1 22537537 1014199 complement(1397550..1399184) 1 NC_004116.1 identified by match to PFAM protein family HMM PF01943; polysaccharide biosynthesis protein 1399184 1014199 SAG1390 Streptococcus agalactiae 2603V/R polysaccharide biosynthesis protein NP_688388.1 1397550 R 208435 CDS NP_688389.1 22537538 1014200 1399308..1400762 1 NC_004116.1 involved in cell wall formation; peptidoglycan synthesis; cytoplasmic enzyme; catalyzes the addition of lysine to UDP-N-acetylmuramoyl-L-alanyl-D-glutamate forming UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysine; UDP-N-acetylmuramoylalanyl-D-glutamate--L-lysine ligase 1400762 murE 1014200 murE Streptococcus agalactiae 2603V/R UDP-N-acetylmuramoylalanyl-D-glutamate--L-lysine ligase NP_688389.1 1399308 D 208435 CDS NP_688390.1 22537539 1014201 1400918..1401712 1 NC_004116.1 identified by match to PFAM protein family HMM PF00005; iron ABC transporter ATP-binding protein 1401712 1014201 SAG1392 Streptococcus agalactiae 2603V/R iron ABC transporter ATP-binding protein NP_688390.1 1400918 D 208435 CDS NP_688391.1 22537540 1014202 1401736..1402668 1 NC_004116.1 identified by match to PFAM protein family HMM PF01497; iron ABC transporter substrate-binding protein 1402668 1014202 SAG1393 Streptococcus agalactiae 2603V/R iron ABC transporter substrate-binding protein NP_688391.1 1401736 D 208435 CDS NP_688392.1 22537541 1014203 1402684..1403709 1 NC_004116.1 identified by match to PFAM protein family HMM PF01032; iron ABC transporter permease 1403709 1014203 SAG1394 Streptococcus agalactiae 2603V/R iron ABC transporter permease NP_688392.1 1402684 D 208435 CDS NP_688393.1 22537542 1014204 1403706..1404707 1 NC_004116.1 identified by match to PFAM protein family HMM PF01032; iron ABC transporter permease 1404707 1014204 SAG1395 Streptococcus agalactiae 2603V/R iron ABC transporter permease NP_688393.1 1403706 D 208435 CDS NP_688394.1 22537543 1014205 complement(1404736..1405389) 1 NC_004116.1 hypothetical protein 1405389 1014205 SAG1396 Streptococcus agalactiae 2603V/R hypothetical protein NP_688394.1 1404736 R 208435 CDS NP_688395.1 22537544 1014206 complement(1405449..1406384) 1 NC_004116.1 catalyzes the hydrolysis of pyrophosphate to phosphate; manganese-dependent inorganic pyrophosphatase 1406384 ppa 1014206 ppa Streptococcus agalactiae 2603V/R manganese-dependent inorganic pyrophosphatase NP_688395.1 1405449 R 208435 CDS NP_688396.1 22537545 1014207 complement(1406501..1407289) 1 NC_004116.1 identified by match to PFAM protein family HMM PF02143; pyruvate formate-lyase-activating enzyme 1407289 pflA-2 1014207 pflA-2 Streptococcus agalactiae 2603V/R pyruvate formate-lyase-activating enzyme NP_688396.1 1406501 R 208435 CDS NP_688397.1 22537546 1014208 complement(1407357..1408691) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00571; hypothetical protein 1408691 1014208 SAG1399 Streptococcus agalactiae 2603V/R hypothetical protein NP_688397.1 1407357 R 208435 CDS NP_688398.1 22537547 1014209 complement(1408871..1409437) 1 NC_004116.1 hypothetical protein 1409437 1014209 SAG1400 Streptococcus agalactiae 2603V/R hypothetical protein NP_688398.1 1408871 R 208435 CDS NP_688399.1 22537548 1014210 complement(1409430..1410365) 1 NC_004116.1 hypothetical protein 1410365 1014210 SAG1401 Streptococcus agalactiae 2603V/R hypothetical protein NP_688399.1 1409430 R 208435 CDS NP_688400.1 22537549 1014211 complement(1410458..1411099) 1 NC_004116.1 identified by match to PFAM protein family HMM PF01569; PAP2 family protein 1411099 1014211 SAG1402 Streptococcus agalactiae 2603V/R PAP2 family protein NP_688400.1 1410458 R 208435 CDS NP_688401.1 22537550 1014212 complement(1411080..1411664) 1 NC_004116.1 similar to OMNI:NTL01SPL0281; identified by sequence similarity; hypothetical protein 1411664 1014212 SAG1403 Streptococcus agalactiae 2603V/R hypothetical protein NP_688401.1 1411080 R 208435 CDS NP_688402.1 22537551 1014213 complement(1411965..1412891) 1 NC_004116.1 identified by match to TIGR protein family HMM TIGR01167; The product of this gene was detected by Western blot analysis. For details on the method see Tettelin et al. 2002.; cell wall surface anchor family protein 1412891 1014213 SAG1404 Streptococcus agalactiae 2603V/R cell wall surface anchor family protein NP_688402.1 1411965 R 208435 CDS NP_688403.1 22537552 1014214 complement(1412888..1413772) 1 NC_004116.1 identified by match to TIGR protein family HMM TIGR01076; The product of this gene was detected by Western blot analysis. For details on the method see Tettelin et al. 2002.; sortase family protein 1413772 1014214 SAG1405 Streptococcus agalactiae 2603V/R sortase family protein NP_688403.1 1412888 R 208435 CDS NP_688404.1 22537553 1014215 complement(1413772..1414653) 1 NC_004116.1 identified by match to TIGR protein family HMM TIGR01076; sortase family protein 1414653 1014215 SAG1406 Streptococcus agalactiae 2603V/R sortase family protein NP_688404.1 1413772 R 208435 CDS NP_688405.1 22537554 1014216 complement(1414765..1416882) 1 NC_004116.1 identified by match to TIGR protein family HMM TIGR01167; The product of this gene was detected by Western blot analysis. For details on the method see Tettelin et al. 2002.; cell wall surface anchor family protein 1416882 1014216 SAG1407 Streptococcus agalactiae 2603V/R cell wall surface anchor family protein NP_688405.1 1414765 R 208435 CDS NP_688406.1 22537555 1014217 complement(1417012..1419717) 1 NC_004116.1 cell wall surface anchor family protein 1419717 1014217 SAG1408 Streptococcus agalactiae 2603V/R cell wall surface anchor family protein NP_688406.1 1417012 R 208435 CDS NP_688407.1 22537556 1014219 complement(1421579..1422718) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00534; glycoside hydrolase family protein 1422718 1014219 SAG1410 Streptococcus agalactiae 2603V/R glycoside hydrolase family protein NP_688407.1 1421579 R 208435 CDS NP_688408.1 22537557 1014220 complement(1422708..1423556) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00535; glycosyl transferase family protein 1423556 1014220 SAG1411 Streptococcus agalactiae 2603V/R glycosyl transferase family protein NP_688408.1 1422708 R 208435 CDS NP_688409.1 22537558 1014221 complement(1423553..1424977) 1 NC_004116.1 identified by match to PFAM protein family HMM PF01943; polysaccharide biosynthesis protein 1424977 1014221 SAG1412 Streptococcus agalactiae 2603V/R polysaccharide biosynthesis protein NP_688409.1 1423553 R 208435 CDS NP_688410.1 22537559 1014222 complement(1424977..1426341) 1 NC_004116.1 hypothetical protein 1426341 1014222 SAG1413 Streptococcus agalactiae 2603V/R hypothetical protein NP_688410.1 1424977 R 208435 CDS NP_688411.1 22537560 1014223 complement(1426343..1427269) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00535; glycosyl transferase family protein 1427269 1014223 SAG1414 Streptococcus agalactiae 2603V/R glycosyl transferase family protein NP_688411.1 1426343 R 208435 CDS NP_688412.1 22537561 1014224 complement(1427299..1428234) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00535; glycosyl transferase family protein 1428234 1014224 SAG1415 Streptococcus agalactiae 2603V/R glycosyl transferase family protein NP_688412.1 1427299 R 208435 CDS NP_688413.1 22537562 1014225 complement(1428236..1429294) 1 NC_004116.1 nucleotide sugar dehydratase 1429294 1014225 SAG1416 Streptococcus agalactiae 2603V/R nucleotide sugar dehydratase NP_688413.1 1428236 R 208435 CDS NP_688414.1 22537563 1014226 complement(1429294..1430016) 1 NC_004116.1 identified by match to PFAM protein family HMM PF01128; nucleotidyl transferase 1430016 1014226 SAG1417 Streptococcus agalactiae 2603V/R nucleotidyl transferase NP_688414.1 1429294 R 208435 CDS NP_688415.1 22537564 1014227 complement(1430016..1430840) 1 NC_004116.1 similar to OMNI:EF2168; identified by sequence similarity; polysaccharide biosynthesis protein 1430840 1014227 SAG1418 Streptococcus agalactiae 2603V/R polysaccharide biosynthesis protein NP_688415.1 1430016 R 208435 CDS NP_688416.1 22537565 1014228 complement(1430865..1432598) 1 NC_004116.1 hypothetical protein 1432598 1014228 SAG1419 Streptococcus agalactiae 2603V/R hypothetical protein NP_688416.1 1430865 R 208435 CDS NP_688417.1 22537566 1014229 complement(1432591..1432944) 1 NC_004116.1 hypothetical protein 1432944 1014229 SAG1420 Streptococcus agalactiae 2603V/R hypothetical protein NP_688417.1 1432591 R 208435 CDS NP_688418.1 22537567 1014230 complement(1432941..1433672) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00535; glycosyl transferase family protein 1433672 1014230 SAG1421 Streptococcus agalactiae 2603V/R glycosyl transferase family protein NP_688418.1 1432941 R 208435 CDS NP_688419.1 22537568 1014231 complement(1433674..1434615) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00535; glycosyl transferase family protein 1434615 1014231 SAG1422 Streptococcus agalactiae 2603V/R glycosyl transferase family protein NP_688419.1 1433674 R 208435 CDS NP_688420.1 22537569 1014232 complement(1434605..1435759) 1 NC_004116.1 glycosyl transferase family protein 1435759 1014232 SAG1423 Streptococcus agalactiae 2603V/R glycosyl transferase family protein NP_688420.1 1434605 R 208435 CDS NP_688421.1 22537570 1014233 complement(1435876..1436730) 1 NC_004116.1 identified by match to TIGR protein family HMM TIGR01214; dTDP-4-dehydrorhamnose reductase 1436730 rfbD 1014233 rfbD Streptococcus agalactiae 2603V/R dTDP-4-dehydrorhamnose reductase NP_688421.1 1435876 R 208435 CDS NP_688422.1 22537571 1014234 complement(1436820..1437161) 1 NC_004116.1 hypothetical protein 1437161 1014234 SAG1425 Streptococcus agalactiae 2603V/R hypothetical protein NP_688422.1 1436820 R 208435 CDS NP_688423.1 22537572 1014235 complement(1437270..1438379) 1 NC_004116.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; primary sigma factor of bacterium; RNA polymerase sigma factor RpoD 1438379 rpoD 1014235 rpoD Streptococcus agalactiae 2603V/R RNA polymerase sigma factor RpoD NP_688423.1 1437270 R 208435 CDS NP_688424.1 22537573 1014236 complement(1438387..1440195) 1 NC_004116.1 synthesizes RNA primers at the replication forks; DNA primase 1440195 dnaG 1014236 dnaG Streptococcus agalactiae 2603V/R DNA primase NP_688424.1 1438387 R 208435 CDS NP_688425.1 22537574 1014237 1440385..1440762 1 NC_004116.1 identified by match to PFAM protein family HMM PF01741; large conductance mechanosensitive channel protein 1440762 mscL 1014237 mscL Streptococcus agalactiae 2603V/R large conductance mechanosensitive channel protein NP_688425.1 1440385 D 208435 CDS NP_688426.1 22537575 1014238 complement(1440859..1441035) 1 NC_004116.1 a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA; 30S ribosomal protein S21 1441035 rpsU 1014238 rpsU Streptococcus agalactiae 2603V/R 30S ribosomal protein S21 NP_688426.1 1440859 R 208435 CDS NP_688427.1 22537576 1014239 complement(1441139..1441642) 1 NC_004116.1 hypothetical protein 1441642 1014239 SAG1430 Streptococcus agalactiae 2603V/R hypothetical protein NP_688427.1 1441139 R 208435 CDS NP_688428.1 22537577 1014240 complement(1441725..1442531) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00497; amino acid ABC transporter amino acid-binding protein 1442531 1014240 SAG1431 Streptococcus agalactiae 2603V/R amino acid ABC transporter amino acid-binding protein NP_688428.1 1441725 R 208435 CDS NP_688429.1 22537578 1014241 complement(1442856..1443899) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00909; ammonium transporter 1443899 1014241 SAG1432 Streptococcus agalactiae 2603V/R ammonium transporter NP_688429.1 1442856 R 208435 CDS NP_688430.1 22537579 1014242 1443979..1445106 1 NC_004116.1 hypothetical protein 1445106 1014242 SAG1433 Streptococcus agalactiae 2603V/R hypothetical protein NP_688430.1 1443979 D 208435 CDS NP_688431.1 22537580 1014243 complement(1445143..1446129) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00581; hypothetical protein 1446129 1014243 SAG1434 Streptococcus agalactiae 2603V/R hypothetical protein NP_688431.1 1445143 R 208435 CDS NP_688432.1 22537581 1014244 1446292..1446597 1 NC_004116.1 hypothetical protein 1446597 1014244 SAG1435 Streptococcus agalactiae 2603V/R hypothetical protein NP_688432.1 1446292 D 208435 CDS NP_688433.1 22537582 1014245 complement(1446755..1448128) 1 NC_004116.1 glycerol-3-phosphate transporter 1448128 1014245 SAG1436 Streptococcus agalactiae 2603V/R glycerol-3-phosphate transporter NP_688433.1 1446755 R 208435 CDS NP_688434.1 22537583 1014246 1448236..1448403 1 NC_004116.1 hypothetical protein 1448403 1014246 SAG1437 Streptococcus agalactiae 2603V/R hypothetical protein NP_688434.1 1448236 D 208435 CDS NP_688435.1 22537584 1014247 complement(1448544..1450808) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00343; glycogen phosphorylase 1450808 glgP 1014247 glgP Streptococcus agalactiae 2603V/R glycogen phosphorylase NP_688435.1 1448544 R 208435 CDS NP_688436.1 22537585 1014248 complement(1450820..1452316) 1 NC_004116.1 amylomaltase; acts to release glucose from maltodextrins; 4-alpha-glucanotransferase 1452316 malQ 1014248 malQ Streptococcus agalactiae 2603V/R 4-alpha-glucanotransferase NP_688436.1 1450820 R 208435 CDS NP_688437.1 22537586 1014249 complement(1452437..1453465) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00356; maltose operon repressor MalR 1453465 1014249 SAG1440 Streptococcus agalactiae 2603V/R maltose operon repressor MalR NP_688437.1 1452437 R 208435 CDS NP_688438.1 22537587 1014250 1453721..1454968 1 NC_004116.1 identified by match to PFAM protein family HMM PF01547; maltose/maltodextrin ABC transporter maltose/maltodextrin-binding protein 1454968 1014250 SAG1441 Streptococcus agalactiae 2603V/R maltose/maltodextrin ABC transporter maltose/maltodextrin-binding protein NP_688438.1 1453721 D 208435 CDS NP_688439.1 22537588 1014251 1455066..1456436 1 NC_004116.1 identified by match to PFAM protein family HMM PF00528; maltose ABC transporter permease 1456436 1014251 SAG1442 Streptococcus agalactiae 2603V/R maltose ABC transporter permease NP_688439.1 1455066 D 208435 CDS NP_688440.1 22537589 1014252 1456436..1457272 1 NC_004116.1 identified by match to PFAM protein family HMM PF00528; maltose ABC transporter permease 1457272 1014252 SAG1443 Streptococcus agalactiae 2603V/R maltose ABC transporter permease NP_688440.1 1456436 D 208435 CDS NP_688441.1 22537590 1014253 1457503..1458975 1 NC_004116.1 identified by match to PFAM protein family HMM PF00854; proton/peptide symporter family protein 1458975 1014253 SAG1444 Streptococcus agalactiae 2603V/R proton/peptide symporter family protein NP_688441.1 1457503 D 208435 CDS NP_688442.1 22537591 1014255 complement(1459557..1459745) 1 NC_004116.1 hypothetical protein 1459745 1014255 SAG1446 Streptococcus agalactiae 2603V/R hypothetical protein NP_688442.1 1459557 R 208435 CDS NP_688443.1 22537592 1014256 complement(1459756..1461081) 1 NC_004116.1 hypothetical protein 1461081 1014256 SAG1447 Streptococcus agalactiae 2603V/R hypothetical protein NP_688443.1 1459756 R 208435 CDS NP_688444.1 22537593 1014257 complement(1461074..1462582) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00534; glycoside hydrolase family protein 1462582 1014257 SAG1448 Streptococcus agalactiae 2603V/R glycoside hydrolase family protein NP_688444.1 1461074 R 208435 CDS NP_688445.1 22537594 1014258 complement(1462596..1464983) 1 NC_004116.1 functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; in some organisms, especially gram positive pathogens, have paralogs that have been found to be nonessential but do function in secretion of a subset of exported proteins; preprotein translocase subunit SecA 1464983 1014258 SAG1449 Streptococcus agalactiae 2603V/R preprotein translocase subunit SecA NP_688445.1 1462596 R 208435 CDS NP_688446.1 22537595 1014259 complement(1464970..1465962) 1 NC_004116.1 similar to OMNI:SP1760; identified by sequence similarity; hypothetical protein 1465962 1014259 SAG1450 Streptococcus agalactiae 2603V/R hypothetical protein NP_688446.1 1464970 R 208435 CDS NP_688447.1 22537596 1014260 complement(1465959..1467443) 1 NC_004116.1 hypothetical protein 1467443 1014260 SAG1451 Streptococcus agalactiae 2603V/R hypothetical protein NP_688447.1 1465959 R 208435 CDS NP_688448.1 22537597 1014261 complement(1467525..1469069) 1 NC_004116.1 hypothetical protein 1469069 1014261 SAG1452 Streptococcus agalactiae 2603V/R hypothetical protein NP_688448.1 1467525 R 208435 CDS NP_688449.1 22537598 1014262 complement(1469069..1470298) 1 NC_004116.1 forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase; preprotein translocase subunit SecY 1470298 secY 1014262 secY Streptococcus agalactiae 2603V/R preprotein translocase subunit SecY NP_688449.1 1469069 R 208435 CDS NP_688450.1 22537599 1014263 complement(1470422..1471618) 1 NC_004116.1 similar to GP:13346801; identified by sequence similarity; hypothetical protein 1471618 1014263 SAG1454 Streptococcus agalactiae 2603V/R hypothetical protein NP_688450.1 1470422 R 208435 CDS NP_688451.1 22537600 1014264 complement(1471679..1472566) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00535; glycosyl transferase family protein 1472566 1014264 SAG1455 Streptococcus agalactiae 2603V/R glycosyl transferase family protein NP_688451.1 1471679 R 208435 CDS NP_688452.1 22537601 1014266 complement(1473647..1474036) 1 NC_004116.1 identified by match to PFAM protein family HMM PF01609; IS1381 transposase protein B 1474036 1014266 SAG1457 Streptococcus agalactiae 2603V/R IS1381 transposase protein B NP_688452.1 1473647 R 208435 CDS NP_688453.1 22537602 1014267 complement(1474069..1474452) 1 NC_004116.1 similar to OMNI:SP0537; identified by sequence similarity; IS1381 transposase protein A 1474452 1014267 SAG1458 Streptococcus agalactiae 2603V/R IS1381 transposase protein A NP_688453.1 1474069 R 208435 CDS NP_688454.1 22537603 1014268 complement(1474581..1475822) 1 NC_004116.1 identified by match to PFAM protein family HMM PF01501; glycosyl transferase family protein 1475822 1014268 SAG1459 Streptococcus agalactiae 2603V/R glycosyl transferase family protein NP_688454.1 1474581 R 208435 CDS NP_688455.1 22537604 1014269 complement(1475819..1477024) 1 NC_004116.1 identified by match to PFAM protein family HMM PF01501; glycosyl transferase family protein 1477024 1014269 SAG1460 Streptococcus agalactiae 2603V/R glycosyl transferase family protein NP_688455.1 1475819 R 208435 CDS NP_688456.1 22537605 1014270 complement(1477033..1478040) 1 NC_004116.1 hypothetical protein 1478040 1014270 SAG1461 Streptococcus agalactiae 2603V/R hypothetical protein NP_688456.1 1477033 R 208435 CDS NP_688457.1 22537606 1014271 complement(1478371..1481283) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00746; cell wall surface anchor family protein 1481283 1014271 SAG1462 Streptococcus agalactiae 2603V/R cell wall surface anchor family protein NP_688457.1 1478371 R 208435 CDS NP_688458.1 22537607 1014273 complement(1483259..1485250) 1 NC_004116.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion; excinuclease ABC subunit B 1485250 uvrB 1014273 uvrB Streptococcus agalactiae 2603V/R excinuclease ABC subunit B NP_688458.1 1483259 R 208435 CDS NP_688459.1 22537608 1014274 complement(1485311..1486231) 1 NC_004116.1 identified by match to PFAM protein family HMM PF02517; protease 1486231 1014274 SAG1465 Streptococcus agalactiae 2603V/R protease NP_688459.1 1485311 R 208435 CDS NP_688460.1 22537609 1014275 1486414..1488597 1 NC_004116.1 identified by match to PFAM protein family HMM PF00497; glutamine ABC transporter glutamine-binding protein/permease 1488597 glnP 1014275 glnP Streptococcus agalactiae 2603V/R glutamine ABC transporter glutamine-binding protein/permease NP_688460.1 1486414 D 208435 CDS NP_688461.1 22537610 1014276 1488597..1489337 1 NC_004116.1 identified by match to PFAM protein family HMM PF00005; glutamine ABC transporter ATP-binding protein, GlnQ 1489337 1014276 SAG1467 Streptococcus agalactiae 2603V/R glutamine ABC transporter ATP-binding protein, GlnQ NP_688461.1 1488597 D 208435 CDS NP_688462.1 22537611 1014277 1489486..1489836 1 NC_004116.1 hypothetical protein 1489836 1014277 SAG1468 Streptococcus agalactiae 2603V/R hypothetical protein NP_688462.1 1489486 D 208435 CDS NP_688463.1 22537612 1014278 complement(1489928..1490086) 1 NC_004116.1 hypothetical protein 1490086 1014278 SAG1469 Streptococcus agalactiae 2603V/R hypothetical protein NP_688463.1 1489928 R 208435 CDS NP_688464.2 161485613 1014279 complement(1490112..1491419) 1 NC_004116.1 essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication; GTPase ObgE 1491419 obgE 1014279 obgE Streptococcus agalactiae 2603V/R GTPase ObgE NP_688464.2 1490112 R 208435 CDS NP_688465.1 22537614 1014280 complement(1491486..1491614) 1 NC_004116.1 hypothetical protein 1491614 1014280 SAG1471 Streptococcus agalactiae 2603V/R hypothetical protein NP_688465.1 1491486 R 208435 CDS NP_688466.1 22537615 1014281 1491811..1493052 1 NC_004116.1 identified by match to PFAM protein family HMM PF02073; aminopeptidase 1493052 pepS 1014281 pepS Streptococcus agalactiae 2603V/R aminopeptidase NP_688466.1 1491811 D 208435 CDS NP_688467.1 22537616 1014282 complement(1493086..1493664) 1 NC_004116.1 identified by match to TIGR protein family HMM TIGR01167; cell wall surface anchor family protein 1493664 1014282 SAG1473 Streptococcus agalactiae 2603V/R cell wall surface anchor family protein NP_688467.1 1493086 R 208435 CDS NP_688468.1 22537617 1014283 complement(1493774..1495816) 1 NC_004116.1 identified by match to PFAM protein family HMM PF01425; amidase 1495816 1014283 SAG1474 Streptococcus agalactiae 2603V/R amidase NP_688468.1 1493774 R 208435 CDS NP_688469.1 22537618 1014284 complement(1495901..1496623) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00849; ribosomal small subunit pseudouridine synthase A 1496623 rsuA 1014284 rsuA Streptococcus agalactiae 2603V/R ribosomal small subunit pseudouridine synthase A NP_688469.1 1495901 R 208435 CDS NP_688470.1 22537619 1014285 complement(1496814..1497656) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00248; aldo/keto reductase 1497656 1014285 SAG1476 Streptococcus agalactiae 2603V/R aldo/keto reductase NP_688470.1 1496814 R 208435 CDS NP_688471.1 22537620 1014286 1497923..1498597 1 NC_004116.1 identified by match to PFAM protein family HMM PF00881; nitroreductase family protein 1498597 1014286 SAG1477 Streptococcus agalactiae 2603V/R nitroreductase family protein NP_688471.1 1497923 D 208435 CDS NP_688472.1 22537621 1014287 1498685..1499077 1 NC_004116.1 identified by match to PFAM protein family HMM PF00903; lactoylglutathione lyase 1499077 gloA 1014287 gloA Streptococcus agalactiae 2603V/R lactoylglutathione lyase NP_688472.1 1498685 D 208435 CDS NP_688473.1 22537622 1014288 1499206..1500132 1 NC_004116.1 identified by match to PFAM protein family HMM PF00535; glycosyl transferase family protein 1500132 1014288 SAG1479 Streptococcus agalactiae 2603V/R glycosyl transferase family protein NP_688473.1 1499206 D 208435 CDS NP_688474.1 22537623 1014289 1500261..1501649 1 NC_004116.1 identified by match to PFAM protein family HMM PF00324; amino acid permease 1501649 1014289 SAG1480 Streptococcus agalactiae 2603V/R amino acid permease NP_688474.1 1500261 D 208435 CDS NP_688475.1 22537624 1014290 complement(1501733..1502200) 1 NC_004116.1 binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation; SsrA-binding protein 1502200 smpB 1014290 smpB Streptococcus agalactiae 2603V/R SsrA-binding protein NP_688475.1 1501733 R 208435 CDS NP_688476.1 22537625 1014291 complement(1502203..1504608) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00575; VacB/Rnb family exoribonuclease 1504608 vacB 1014291 vacB Streptococcus agalactiae 2603V/R VacB/Rnb family exoribonuclease NP_688476.1 1502203 R 208435 CDS NP_688477.1 22537626 1014292 complement(1504721..1504957) 1 NC_004116.1 preprotein translocase subunit SecG 1504957 secG 1014292 secG Streptococcus agalactiae 2603V/R preprotein translocase subunit SecG NP_688477.1 1504721 R 208435 CDS NP_688478.1 22537627 1014293 complement(1505004..1505150) 1 NC_004116.1 in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif; 50S ribosomal protein L33 1505150 rpmG 1014293 rpmG Streptococcus agalactiae 2603V/R 50S ribosomal protein L33 NP_688478.1 1505004 R 208435 CDS NP_688479.1 22537628 1014294 complement(1505147..1506316) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00083; multi-drug resistance protein 1506316 1014294 SAG1485 Streptococcus agalactiae 2603V/R multi-drug resistance protein NP_688479.1 1505147 R 208435 CDS NP_688480.1 22537629 1014295 complement(1506512..1508158) 1 NC_004116.1 hypothetical protein 1508158 1014295 SAG1486 Streptococcus agalactiae 2603V/R hypothetical protein NP_688480.1 1506512 R 208435 CDS NP_688481.1 22537630 1014296 complement(1508148..1508849) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00005; ABC transporter ATP-binding protein 1508849 1014296 SAG1487 Streptococcus agalactiae 2603V/R ABC transporter ATP-binding protein NP_688481.1 1508148 R 208435 CDS NP_688482.1 22537631 1014297 complement(1508973..1509560) 1 NC_004116.1 catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; involved in coenzyme A biosynthesis; dephospho-CoA kinase 1509560 coaE 1014297 coaE Streptococcus agalactiae 2603V/R dephospho-CoA kinase NP_688482.1 1508973 R 208435 CDS NP_688483.1 22537632 1014298 complement(1509557..1510378) 1 NC_004116.1 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases; formamidopyrimidine-DNA glycosylase 1510378 mutM 1014298 mutM Streptococcus agalactiae 2603V/R formamidopyrimidine-DNA glycosylase NP_688483.1 1509557 R 208435 CDS NP_688484.1 22537633 1014299 complement(1510527..1511375) 1 NC_004116.1 identified by match to PFAM protein family HMM PF01381; MutR family transcriptional regulator 1511375 1014299 SAG1490 Streptococcus agalactiae 2603V/R MutR family transcriptional regulator NP_688484.1 1510527 R 208435 CDS NP_688485.1 22537634 1014300 1511592..1513184 1 NC_004116.1 hypothetical protein 1513184 1014300 SAG1491 Streptococcus agalactiae 2603V/R hypothetical protein NP_688485.1 1511592 D 208435 CDS NP_688486.1 22537635 1014301 1513220..1513396 1 NC_004116.1 hypothetical protein 1513396 1014301 SAG1492 Streptococcus agalactiae 2603V/R hypothetical protein NP_688486.1 1513220 D 208435 CDS NP_688487.1 22537636 1014302 complement(1513447..1513647) 1 NC_004116.1 hypothetical protein 1513647 1014302 SAG1493 Streptococcus agalactiae 2603V/R hypothetical protein NP_688487.1 1513447 R 208435 CDS NP_688488.1 22537637 1014303 complement(1513840..1513938) 1 NC_004116.1 hypothetical protein 1513938 1014303 SAG1494 Streptococcus agalactiae 2603V/R hypothetical protein NP_688488.1 1513840 R 208435 CDS NP_688489.1 22537638 1014304 complement(1514173..1514418) 1 NC_004116.1 identified by match to PFAM protein family HMM PF02517; CAAX amino terminal protease family protein 1514418 1014304 SAG1495 Streptococcus agalactiae 2603V/R CAAX amino terminal protease family protein NP_688489.1 1514173 R 208435 CDS NP_688490.1 22537639 1014305 complement(1514446..1514778) 1 NC_004116.1 hypothetical protein 1514778 1014305 SAG1496 Streptococcus agalactiae 2603V/R hypothetical protein NP_688490.1 1514446 R 208435 CDS NP_688491.1 22537640 1014306 complement(1514880..1514993) 1 NC_004116.1 hypothetical protein 1514993 1014306 SAG1497 Streptococcus agalactiae 2603V/R hypothetical protein NP_688491.1 1514880 R 208435 CDS NP_688492.1 22537641 1014307 complement(1515157..1515558) 1 NC_004116.1 hypothetical protein 1515558 1014307 SAG1498 Streptococcus agalactiae 2603V/R hypothetical protein NP_688492.1 1515157 R 208435 CDS NP_688493.1 22537642 1014308 complement(1515795..1516694) 1 NC_004116.1 Era; Escherichia coli Ras-like protein; Bex; Bacillus Era-complementing segment; essential protein in Escherichia coli that is involved in many cellular processes; GTPase; binds the cell membrane through apparent C-terminal domain; mutants are arrested during the cell cycle; Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome; GTP-binding protein Era 1516694 era 1014308 era Streptococcus agalactiae 2603V/R GTP-binding protein Era NP_688493.1 1515795 R 208435 CDS NP_688494.1 22537643 1014309 complement(1516736..1517134) 1 NC_004116.1 identified by match to PFAM protein family HMM PF01219; diacylglycerol kinase 1517134 dgkA 1014309 dgkA Streptococcus agalactiae 2603V/R diacylglycerol kinase NP_688494.1 1516736 R 208435 CDS NP_688495.1 22537644 1014310 complement(1517115..1517600) 1 NC_004116.1 metalloprotease 1517600 1014310 SAG1501 Streptococcus agalactiae 2603V/R metalloprotease NP_688495.1 1517115 R 208435 CDS NP_688496.1 22537645 1014311 complement(1518007..1518813) 1 NC_004116.1 similar to SP:P39887; identified by sequence similarity; tetracenomycin polyketide synthesis O-methyltransferase TcmP 1518813 1014311 SAG1502 Streptococcus agalactiae 2603V/R tetracenomycin polyketide synthesis O-methyltransferase TcmP NP_688496.1 1518007 R 208435 CDS NP_688497.1 22537646 1014312 complement(1518858..1518977) 1 NC_004116.1 hypothetical protein 1518977 1014312 SAG1503 Streptococcus agalactiae 2603V/R hypothetical protein NP_688497.1 1518858 R 208435 CDS NP_688498.1 22537647 1014313 complement(1519014..1519130) 1 NC_004116.1 hypothetical protein 1519130 1014313 SAG1504 Streptococcus agalactiae 2603V/R hypothetical protein NP_688498.1 1519014 R 208435 CDS NP_688499.1 22537648 1014314 complement(1519135..1519611) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00293; MutT/nudix family protein 1519611 1014314 SAG1505 Streptococcus agalactiae 2603V/R MutT/nudix family protein NP_688499.1 1519135 R 208435 CDS NP_688500.1 22537649 1014315 1519803..1520606 1 NC_004116.1 hypothetical protein 1520606 1014315 SAG1506 Streptococcus agalactiae 2603V/R hypothetical protein NP_688500.1 1519803 D 208435 CDS NP_688501.1 22537650 1014316 complement(1520697..1521734) 1 NC_004116.1 identified by match to PFAM protein family HMM PF02562; PhoH family protein 1521734 1014316 SAG1507 Streptococcus agalactiae 2603V/R PhoH family protein NP_688501.1 1520697 R 208435 CDS NP_688502.1 22537651 1014317 complement(1521807..1523579) 1 NC_004116.1 in group A Streptococci this protein was found to cross react with anti myosin antibodies and may play a role in rheumatic fever; hypothetical protein 1523579 1014317 SAG1508 Streptococcus agalactiae 2603V/R hypothetical protein NP_688502.1 1521807 R 208435 CDS NP_688503.1 22537652 1014318 complement(1523736..1523951) 1 NC_004116.1 hypothetical protein 1523951 1014318 SAG1509 Streptococcus agalactiae 2603V/R hypothetical protein NP_688503.1 1523736 R 208435 CDS NP_688504.1 22537653 1014319 complement(1523948..1524457) 1 NC_004116.1 this stereospecific enzymes reduces the S isomer of methionine sulfoxide while MsrB reduces the R form; provides protection against oxidative stress; methionine sulfoxide reductase A 1524457 msrA 1014319 msrA Streptococcus agalactiae 2603V/R methionine sulfoxide reductase A NP_688504.1 1523948 R 208435 CDS NP_688505.1 22537654 1014320 complement(1524595..1525449) 1 NC_004116.1 hypothetical protein 1525449 1014320 SAG1511 Streptococcus agalactiae 2603V/R hypothetical protein NP_688505.1 1524595 R 208435 CDS NP_688506.1 22537655 1014321 complement(1525567..1526124) 1 NC_004116.1 Rrf; Frr; ribosome-recycling factor; release factor 4; RF4; recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G; A GTPase-dependent process results in release of 50S from 70S; inhibited by release factor RF-1; essential for viability; structurally similar to tRNAs; ribosome recycling factor 1526124 frr 1014321 frr Streptococcus agalactiae 2603V/R ribosome recycling factor NP_688506.1 1525567 R 208435 CDS NP_688507.1 22537656 1014322 complement(1526140..1526868) 1 NC_004116.1 Catalyzes the phosphorylation of UMP to UDP; uridylate kinase 1526868 pyrH 1014322 pyrH Streptococcus agalactiae 2603V/R uridylate kinase NP_688507.1 1526140 R 208435 CDS NP_688508.1 22537657 1014323 complement(1526989..1527669) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00005; peptide ABC transporter ATP-binding protein 1527669 1014323 SAG1514 Streptococcus agalactiae 2603V/R peptide ABC transporter ATP-binding protein NP_688508.1 1526989 R 208435 CDS NP_688509.1 22537658 1014324 complement(1527656..1528444) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00005; peptide ABC transporter ATP-binding protein 1528444 1014324 SAG1515 Streptococcus agalactiae 2603V/R peptide ABC transporter ATP-binding protein NP_688509.1 1527656 R 208435 CDS NP_688510.1 22537659 1014325 complement(1528432..1529199) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00528; peptide ABC transporter permease 1529199 1014325 SAG1516 Streptococcus agalactiae 2603V/R peptide ABC transporter permease NP_688510.1 1528432 R 208435 CDS NP_688511.1 22537660 1014326 complement(1529238..1530182) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00528; peptide ABC transporter permease 1530182 1014326 SAG1517 Streptococcus agalactiae 2603V/R peptide ABC transporter permease NP_688511.1 1529238 R 208435 CDS NP_688512.1 22537661 1014327 complement(1530169..1531785) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00496; peptide ABC transporter substrate-binding protein 1531785 1014327 SAG1518 Streptococcus agalactiae 2603V/R peptide ABC transporter substrate-binding protein NP_688512.1 1530169 R 208435 CDS NP_688513.1 22537662 1014328 complement(1532174..1532863) 1 NC_004116.1 in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA; 50S ribosomal protein L1 1532863 rplA 1014328 rplA Streptococcus agalactiae 2603V/R 50S ribosomal protein L1 NP_688513.1 1532174 R 208435 CDS NP_688514.1 22537663 1014329 complement(1532967..1533392) 1 NC_004116.1 binds directly to 23S ribosomal RNA; 50S ribosomal protein L11 1533392 rplK 1014329 rplK Streptococcus agalactiae 2603V/R 50S ribosomal protein L11 NP_688514.1 1532967 R 208435 CDS NP_688515.1 22537664 1014330 1533654..1534820 1 NC_004116.1 identified by match to PFAM protein family HMM PF00665; IS30 family transposase 1534820 1014330 SAG1521 Streptococcus agalactiae 2603V/R IS30 family transposase NP_688515.1 1533654 D 208435 CDS NP_688516.1 22537665 1014331 complement(1535154..1536536) 1 NC_004116.1 major facilitator transporter 1536536 1014331 SAG1522 Streptococcus agalactiae 2603V/R major facilitator transporter NP_688516.1 1535154 R 208435 CDS NP_688517.1 22537666 1014332 complement(1536544..1537758) 1 NC_004116.1 identified by match to PFAM protein family HMM PF01546; M20/M25/M40 family peptidase 1537758 1014332 SAG1523 Streptococcus agalactiae 2603V/R M20/M25/M40 family peptidase NP_688517.1 1536544 R 208435 CDS NP_688518.1 22537667 1014333 1538037..1538921 1 NC_004116.1 identified by match to PFAM protein family HMM PF00126; LysR family transcriptional regulator 1538921 1014333 SAG1524 Streptococcus agalactiae 2603V/R LysR family transcriptional regulator NP_688518.1 1538037 D 208435 CDS NP_688519.1 22537668 1014334 1538982..1539335 1 NC_004116.1 hypothetical protein 1539335 1014334 SAG1525 Streptococcus agalactiae 2603V/R hypothetical protein NP_688519.1 1538982 D 208435 CDS NP_688520.1 22537669 1014335 1539406..1539942 1 NC_004116.1 IS861, transposase OrfA 1539942 1014335 SAG1526 Streptococcus agalactiae 2603V/R IS861, transposase OrfA NP_688520.1 1539406 D 208435 CDS NP_688521.1 22537670 1014336 1539918..1540751 1 NC_004116.1 identified by match to PFAM protein family HMM PF00665; IS861, transposase OrfB 1540751 1014336 SAG1527 Streptococcus agalactiae 2603V/R IS861, transposase OrfB NP_688521.1 1539918 D 208435 CDS NP_688522.1 22537671 1014337 complement(1540800..1542515) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00425; chorismate binding protein 1542515 1014337 SAG1528 Streptococcus agalactiae 2603V/R chorismate binding protein NP_688522.1 1540800 R 208435 CDS NP_688523.1 22537672 1014338 complement(1542597..1545047) 1 NC_004116.1 identified by match to PFAM protein family HMM PF01580; DNA translocase FtsK 1545047 1014338 SAG1529 Streptococcus agalactiae 2603V/R DNA translocase FtsK NP_688523.1 1542597 R 208435 CDS NP_688524.1 22537673 1014339 1545213..1546016 1 NC_004116.1 identified by match to PFAM protein family HMM PF00160; cyclophilin type peptidyl-prolyl cis-trans isomerase 1546016 1014339 SAG1530 Streptococcus agalactiae 2603V/R cyclophilin type peptidyl-prolyl cis-trans isomerase NP_688524.1 1545213 D 208435 CDS NP_688525.1 22537674 1014340 complement(1546068..1546901) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00950; manganese ABC transporter permease 1546901 1014340 SAG1531 Streptococcus agalactiae 2603V/R manganese ABC transporter permease NP_688525.1 1546068 R 208435 CDS NP_688526.1 22537675 1014341 complement(1546903..1547619) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00005; manganese ABC transporter ATP-binding protein 1547619 1014341 SAG1532 Streptococcus agalactiae 2603V/R manganese ABC transporter ATP-binding protein NP_688526.1 1546903 R 208435 CDS NP_688527.1 22537676 1014342 complement(1547790..1548716) 1 NC_004116.1 identified by match to PFAM protein family HMM PF01297; manganese ABC transporter manganese-binding adhesion liprotein 1548716 1014342 SAG1533 Streptococcus agalactiae 2603V/R manganese ABC transporter manganese-binding adhesion liprotein NP_688527.1 1547790 R 208435 CDS NP_688528.1 22537677 1014343 1548883..1549530 1 NC_004116.1 identified by match to PFAM protein family HMM PF01325; iron-dependent transcriptional regulator 1549530 1014343 SAG1534 Streptococcus agalactiae 2603V/R iron-dependent transcriptional regulator NP_688528.1 1548883 D 208435 CDS NP_688529.1 22537678 1014344 complement(1549570..1550259) 1 NC_004116.1 enables the cleavage of the glycosidic bond in both 5'-methylthioadenosine and S-adenosylhomocysteine; 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase 1550259 pfs 1014344 pfs Streptococcus agalactiae 2603V/R 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase NP_688529.1 1549570 R 208435 CDS NP_688530.1 22537679 1014345 complement(1550269..1550538) 1 NC_004116.1 hypothetical protein 1550538 1014345 SAG1536 Streptococcus agalactiae 2603V/R hypothetical protein NP_688530.1 1550269 R 208435 CDS NP_688531.1 22537680 1014346 complement(1550538..1551092) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00293; MutT/nudix family protein 1551092 1014346 SAG1537 Streptococcus agalactiae 2603V/R MutT/nudix family protein NP_688531.1 1550538 R 208435 CDS NP_688532.1 22537681 1014347 complement(1551113..1552492) 1 NC_004116.1 forms a homotrimer; catalyzes the acetylation of glucosamine-1-phosphate and uridylation of N-acetylglucosamine-1-phosphate to produce UDP-GlcNAc; function in cell wall synthesis; bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase 1552492 glmU 1014347 glmU Streptococcus agalactiae 2603V/R bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase NP_688532.1 1551113 R 208435 CDS NP_688533.1 22537682 1014348 1552634..1552729 1 NC_004116.1 hypothetical protein 1552729 1014348 SAG1539 Streptococcus agalactiae 2603V/R hypothetical protein NP_688533.1 1552634 D 208435 CDS NP_688534.1 22537683 1014349 complement(1552736..1553149) 1 NC_004116.1 hypothetical protein 1553149 1014349 SAG1540 Streptococcus agalactiae 2603V/R hypothetical protein NP_688534.1 1552736 R 208435 CDS NP_688535.1 22537684 1014350 complement(1553162..1553539) 1 NC_004116.1 glyoxylase 1553539 1014350 SAG1541 Streptococcus agalactiae 2603V/R glyoxylase NP_688535.1 1553162 R 208435 CDS NP_688536.1 22537685 1014351 complement(1553628..1554584) 1 NC_004116.1 identified by match to PFAM protein family HMM PF01408; Gfo/Idh/MocA family oxidoreductase 1554584 1014351 SAG1542 Streptococcus agalactiae 2603V/R Gfo/Idh/MocA family oxidoreductase NP_688536.1 1553628 R 208435 CDS NP_688537.1 22537686 1014353 complement(1555271..1555969) 1 NC_004116.1 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis; 3-ketoacyl-ACP reductase 1555969 fabG 1014353 fabG Streptococcus agalactiae 2603V/R 3-ketoacyl-ACP reductase NP_688537.1 1555271 R 208435 CDS NP_688538.1 22537687 1014354 complement(1555962..1556198) 1 NC_004116.1 hypothetical protein 1556198 1014354 SAG1545 Streptococcus agalactiae 2603V/R hypothetical protein NP_688538.1 1555962 R 208435 CDS NP_688539.1 22537688 1014355 complement(1556288..1556536) 1 NC_004116.1 hypothetical protein 1556536 1014355 SAG1546 Streptococcus agalactiae 2603V/R hypothetical protein NP_688539.1 1556288 R 208435 CDS NP_688540.1 22537689 1014356 complement(1556734..1557234) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00583; acetyltransferase 1557234 1014356 SAG1547 Streptococcus agalactiae 2603V/R acetyltransferase NP_688540.1 1556734 R 208435 CDS NP_688541.1 22537690 1014357 complement(1557474..1558742) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00535; glycosyl transferase family protein 1558742 1014357 SAG1548 Streptococcus agalactiae 2603V/R glycosyl transferase family protein NP_688541.1 1557474 R 208435 CDS NP_688542.1 22537691 1014358 1558750..1559133 1 NC_004116.1 similar to OMNI:SP0537; identified by sequence similarity; IS1381 transposase protein A 1559133 1014358 SAG1549 Streptococcus agalactiae 2603V/R IS1381 transposase protein A NP_688542.1 1558750 D 208435 CDS NP_688543.1 22537692 1014359 1559166..1559555 1 NC_004116.1 identified by match to PFAM protein family HMM PF01609; IS1381 transposase protein B 1559555 1014359 SAG1550 Streptococcus agalactiae 2603V/R IS1381 transposase protein B NP_688543.1 1559166 D 208435 CDS NP_688544.1 22537693 1014360 complement(1559544..1559747) 1 NC_004116.1 hypothetical protein 1559747 1014360 SAG1551 Streptococcus agalactiae 2603V/R hypothetical protein NP_688544.1 1559544 R 208435 CDS NP_688545.1 22537694 1014361 complement(1559887..1562046) 1 NC_004116.1 hypothetical protein 1562046 1014361 SAG1552 Streptococcus agalactiae 2603V/R hypothetical protein NP_688545.1 1559887 R 208435 CDS NP_688546.1 22537695 1014362 complement(1562053..1563486) 1 NC_004116.1 hypothetical protein 1563486 1014362 SAG1553 Streptococcus agalactiae 2603V/R hypothetical protein NP_688546.1 1562053 R 208435 CDS NP_688547.1 22537696 1014363 complement(1563491..1564168) 1 NC_004116.1 hypothetical protein 1564168 1014363 SAG1554 Streptococcus agalactiae 2603V/R hypothetical protein NP_688547.1 1563491 R 208435 CDS NP_688548.1 22537697 1014364 complement(1564220..1564915) 1 NC_004116.1 hypothetical protein 1564915 1014364 SAG1555 Streptococcus agalactiae 2603V/R hypothetical protein NP_688548.1 1564220 R 208435 CDS NP_688549.1 22537698 1014365 complement(1565281..1566618) 1 NC_004116.1 identified by match to TIGR protein family HMM TIGR00796; branched-chain amino acid transport system II carrier protein 1566618 brnQ-1 1014365 brnQ-1 Streptococcus agalactiae 2603V/R branched-chain amino acid transport system II carrier protein NP_688549.1 1565281 R 208435 CDS NP_688550.1 22537699 1014366 complement(1566814..1568811) 1 NC_004116.1 methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content; methionyl-tRNA synthetase 1568811 metG 1014366 metG Streptococcus agalactiae 2603V/R methionyl-tRNA synthetase NP_688550.1 1566814 R 208435 CDS NP_688551.1 22537700 1014367 1568954..1569829 1 NC_004116.1 with TehA confers resistance to tellurite; tellurite resistance protein TehB 1569829 tehB 1014367 tehB Streptococcus agalactiae 2603V/R tellurite resistance protein TehB NP_688551.1 1568954 D 208435 CDS NP_688552.1 22537701 1014368 complement(1569987..1570682) 1 NC_004116.1 similar to OMNI:NTL01SPL0310; identified by sequence similarity; hypothetical protein 1570682 1014368 SAG1559 Streptococcus agalactiae 2603V/R hypothetical protein NP_688552.1 1569987 R 208435 CDS NP_688553.1 22537702 1014369 complement(1570697..1570819) 1 NC_004116.1 hypothetical protein 1570819 1014369 SAG1560 Streptococcus agalactiae 2603V/R hypothetical protein NP_688553.1 1570697 R 208435 CDS NP_688554.1 22537703 1014370 1571018..1572235 1 NC_004116.1 PTS system transporter subunit IIC 1572235 1014370 SAG1561 Streptococcus agalactiae 2603V/R PTS system transporter subunit IIC NP_688554.1 1571018 D 208435 CDS NP_688555.1 22537704 1014371 1572219..1573061 1 NC_004116.1 hypothetical protein 1573061 1014371 SAG1562 Streptococcus agalactiae 2603V/R hypothetical protein NP_688555.1 1572219 D 208435 CDS NP_688556.1 22537705 1014372 1573138..1573965 1 NC_004116.1 identified by match to PFAM protein family HMM PF01260; In Gram negative bacteria, the apparent functional equivalent is known as exodeoxyribonuclease III (xth).; exodeoxyribonuclease 1573965 exoA 1014372 exoA Streptococcus agalactiae 2603V/R exodeoxyribonuclease NP_688556.1 1573138 D 208435 CDS NP_688557.1 22537706 1014373 complement(1574005..1574361) 1 NC_004116.1 hypothetical protein 1574361 1014373 SAG1564 Streptococcus agalactiae 2603V/R hypothetical protein NP_688557.1 1574005 R 208435 CDS NP_688558.1 22537707 1014374 complement(1574363..1574839) 1 NC_004116.1 identified by match to PFAM protein family HMM PF01035; methylated-DNA--protein-cysteine S-methyltransferase 1574839 ogt 1014374 ogt Streptococcus agalactiae 2603V/R methylated-DNA--protein-cysteine S-methyltransferase NP_688558.1 1574363 R 208435 CDS NP_688559.1 22537708 1014375 complement(1574894..1576075) 1 NC_004116.1 identified by match to PFAM protein family HMM PF01842; D-isomer specific 2-hydroxyacid dehydrogenase family protein 1576075 1014375 SAG1566 Streptococcus agalactiae 2603V/R D-isomer specific 2-hydroxyacid dehydrogenase family protein NP_688559.1 1574894 R 208435 CDS NP_688560.1 22537709 1014376 complement(1576138..1576686) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00583; acetyltransferase 1576686 1014376 SAG1567 Streptococcus agalactiae 2603V/R acetyltransferase NP_688560.1 1576138 R 208435 CDS NP_688561.1 22537710 1014378 1577979..1578614 1 NC_004116.1 similar to SP:P46719; identified by sequence similarity; copper homeostasis protein CutC 1578614 1014378 SAG1569 Streptococcus agalactiae 2603V/R copper homeostasis protein CutC NP_688561.1 1577979 D 208435 CDS NP_688562.1 22537711 1014379 complement(1578658..1578762) 1 NC_004116.1 hypothetical protein 1578762 1014379 SAG1570 Streptococcus agalactiae 2603V/R hypothetical protein NP_688562.1 1578658 R 208435 CDS NP_688563.1 22537712 1014380 1578747..1578908 1 NC_004116.1 hypothetical protein 1578908 1014380 SAG1571 Streptococcus agalactiae 2603V/R hypothetical protein NP_688563.1 1578747 D 208435 CDS NP_688564.1 22537713 1014381 complement(1578884..1579747) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00590; tetrapyrrole methylase family protein 1579747 1014381 SAG1572 Streptococcus agalactiae 2603V/R tetrapyrrole methylase family protein NP_688564.1 1578884 R 208435 CDS NP_688565.1 22537714 1014382 complement(1579753..1580079) 1 NC_004116.1 in Bacillus subtilis this protein is involved in the negative regulation of DNA replication initiation; interacts with DnaN and DnaA; DNA replication intiation control protein YabA 1580079 1014382 SAG1573 Streptococcus agalactiae 2603V/R DNA replication intiation control protein YabA NP_688565.1 1579753 R 208435 CDS NP_688566.1 22537715 1014383 complement(1580109..1580972) 1 NC_004116.1 catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the delta' subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA.; DNA polymerase III subunit delta' 1580972 1014383 SAG1574 Streptococcus agalactiae 2603V/R DNA polymerase III subunit delta' NP_688566.1 1580109 R 208435 CDS NP_688567.1 22537716 1014384 complement(1580992..1581627) 1 NC_004116.1 catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to thymidine monophosphate (dTMP) to form thymidine diphosphate (dTDP); thymidylate kinase 1581627 tmk 1014384 tmk Streptococcus agalactiae 2603V/R thymidylate kinase NP_688567.1 1580992 R 208435 CDS NP_688568.1 22537717 1014386 complement(1583268..1583927) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00571; AcuB family protein 1583927 1014386 SAG1577 Streptococcus agalactiae 2603V/R AcuB family protein NP_688568.1 1583268 R 208435 CDS NP_688569.1 22537718 1014387 complement(1583946..1584656) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00005; branched-chain amino acid ABC transporter ATP-binding protein 1584656 livF 1014387 livF Streptococcus agalactiae 2603V/R branched-chain amino acid ABC transporter ATP-binding protein NP_688569.1 1583946 R 208435 CDS NP_688570.1 22537719 1014388 complement(1584656..1585420) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00005; branched-chain amino acid ABC transporter ATP-binding protein 1585420 livG 1014388 livG Streptococcus agalactiae 2603V/R branched-chain amino acid ABC transporter ATP-binding protein NP_688570.1 1584656 R 208435 CDS NP_688571.1 22537720 1014389 complement(1585421..1586374) 1 NC_004116.1 identified by match to PFAM protein family HMM PF02653; branched-chain amino acid ABC transporter permease 1586374 1014389 SAG1580 Streptococcus agalactiae 2603V/R branched-chain amino acid ABC transporter permease NP_688571.1 1585421 R 208435 CDS NP_688572.1 22537721 1014390 complement(1586377..1587246) 1 NC_004116.1 identified by match to PFAM protein family HMM PF02653; branched-chain amino acid ABC transporter permease 1587246 livH 1014390 livH Streptococcus agalactiae 2603V/R branched-chain amino acid ABC transporter permease NP_688572.1 1586377 R 208435 CDS NP_688573.1 22537722 1014391 complement(1587352..1588518) 1 NC_004116.1 branched-chain amino acid ABC transporter substrate-binding protein 1588518 1014391 SAG1582 Streptococcus agalactiae 2603V/R branched-chain amino acid ABC transporter substrate-binding protein NP_688573.1 1587352 R 208435 CDS NP_688574.1 22537723 1014392 complement(1588673..1588918) 1 NC_004116.1 hypothetical protein 1588918 1014392 SAG1583 Streptococcus agalactiae 2603V/R hypothetical protein NP_688574.1 1588673 R 208435 CDS NP_688575.1 22537724 1014393 complement(1589092..1590225) 1 NC_004116.1 identified by match to PFAM protein family HMM PF01609; IS1548 transposase 1590225 1014393 SAG1584 Streptococcus agalactiae 2603V/R IS1548 transposase NP_688575.1 1589092 R 208435 CDS NP_688576.1 22537725 1014394 complement(1590344..1590934) 1 NC_004116.1 hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates; ATP-dependent Clp protease proteolytic subunit 1590934 clpP 1014394 clpP Streptococcus agalactiae 2603V/R ATP-dependent Clp protease proteolytic subunit NP_688576.1 1590344 R 208435 CDS NP_688577.1 22537726 1014395 complement(1591059..1591688) 1 NC_004116.1 Catalyzes the formation of uracil and 5-phospho-alpha-D-ribosy 1-diphosphate from UMP and diphosphate; uracil phosphoribosyltransferase 1591688 upp 1014395 upp Streptococcus agalactiae 2603V/R uracil phosphoribosyltransferase NP_688577.1 1591059 R 208435 CDS NP_688578.1 22537727 1014396 complement(1591798..1592967) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00155; class I aminotransferase 1592967 1014396 SAG1587 Streptococcus agalactiae 2603V/R class I aminotransferase NP_688578.1 1591798 R 208435 CDS NP_688579.1 22537728 1014397 complement(1593103..1593651) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00588; RNA methyltransferase 1593651 1014397 SAG1588 Streptococcus agalactiae 2603V/R RNA methyltransferase NP_688579.1 1593103 R 208435 CDS NP_688580.1 22537729 1014398 complement(1593824..1595176) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00324; amino acid permease 1595176 1014398 SAG1589 Streptococcus agalactiae 2603V/R amino acid permease NP_688580.1 1593824 R 208435 CDS NP_688581.1 22537730 1014399 1595382..1596731 1 NC_004116.1 involved in potassium uptake; found to be peripherally associated with the inner membrane in Escherichia coli; contains an NAD-binding domain; potassium transporter peripheral membrane protein 1596731 trkA 1014399 trkA Streptococcus agalactiae 2603V/R potassium transporter peripheral membrane protein NP_688581.1 1595382 D 208435 CDS NP_688582.1 22537731 1014400 1596748..1598175 1 NC_004116.1 identified by match to PFAM protein family HMM PF02386; cation uptake protein 1598175 1014400 SAG1591 Streptococcus agalactiae 2603V/R cation uptake protein NP_688582.1 1596748 D 208435 CDS NP_688583.1 22537732 1014401 complement(1598199..1598450) 1 NC_004116.1 hypothetical protein 1598450 1014401 SAG1592 Streptococcus agalactiae 2603V/R hypothetical protein NP_688583.1 1598199 R 208435 CDS NP_688584.1 22537733 1014402 complement(1598450..1599172) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00849; ribosomal large subunit pseudouridine synthase B 1599172 rluB 1014402 rluB Streptococcus agalactiae 2603V/R ribosomal large subunit pseudouridine synthase B NP_688584.1 1598450 R 208435 CDS NP_688585.1 22537734 1014403 complement(1599162..1599746) 1 NC_004116.1 functions during chromosome segregation; may form a condensin-like structure with SMC and ScpA; forms a homodimer; segregation and condensation protein B 1599746 scpB 1014403 scpB Streptococcus agalactiae 2603V/R segregation and condensation protein B NP_688585.1 1599162 R 208435 CDS NP_688586.1 22537735 1014404 complement(1599743..1600450) 1 NC_004116.1 functions during chromosome segregation; may form a condensin-like structure with SMC and ScpB; segregation and condensation protein A 1600450 scpA 1014404 scpA Streptococcus agalactiae 2603V/R segregation and condensation protein A NP_688586.1 1599743 R 208435 CDS NP_688587.1 22537736 1014405 complement(1600450..1601190) 1 NC_004116.1 site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs; site-specific tyrosine recombinase XerD 1601190 xerD 1014405 xerD Streptococcus agalactiae 2603V/R site-specific tyrosine recombinase XerD NP_688587.1 1600450 R 208435 CDS NP_688588.1 22537737 1014406 complement(1601180..1601653) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00571; hypothetical protein 1601653 1014406 SAG1597 Streptococcus agalactiae 2603V/R hypothetical protein NP_688588.1 1601180 R 208435 CDS NP_688589.1 22537738 1014407 complement(1601650..1602171) 1 NC_004116.1 hypothetical protein 1602171 1014407 SAG1598 Streptococcus agalactiae 2603V/R hypothetical protein NP_688589.1 1601650 R 208435 CDS NP_688590.1 22537739 1014408 complement(1602153..1603127) 1 NC_004116.1 HAM1-like protein; Rec-dependent growth; RgdB; yggV; it is suspected that this protein functions to remove misincorporated bases such as xanthine or hypoxanthine; deoxyribonucleotide triphosphate pyrophosphatase/unknown domain fusion protein 1603127 1014408 SAG1599 Streptococcus agalactiae 2603V/R deoxyribonucleotide triphosphate pyrophosphatase/unknown domain fusion protein NP_688590.1 1602153 R 208435 CDS NP_688591.1 22537740 1014409 complement(1603124..1603918) 1 NC_004116.1 converts L-glutamate to D-glutamate, a component of peptidoglycan; glutamate racemase 1603918 murI 1014409 murI Streptococcus agalactiae 2603V/R glutamate racemase NP_688591.1 1603124 R 208435 CDS NP_688592.1 22537741 1014410 complement(1604093..1604332) 1 NC_004116.1 hypothetical protein 1604332 1014410 SAG1601 Streptococcus agalactiae 2603V/R hypothetical protein NP_688592.1 1604093 R 208435 CDS NP_688593.1 22537742 1014411 complement(1604490..1605032) 1 NC_004116.1 similar to OMNI:NTL01SPL1119; identified by sequence similarity; hypothetical protein 1605032 1014411 SAG1602 Streptococcus agalactiae 2603V/R hypothetical protein NP_688593.1 1604490 R 208435 CDS NP_688594.1 22537743 1014412 complement(1605094..1605615) 1 NC_004116.1 identified by match to PFAM protein family HMM PF02829; biotin repressor family transcriptional regulator 1605615 1014412 SAG1603 Streptococcus agalactiae 2603V/R biotin repressor family transcriptional regulator NP_688594.1 1605094 R 208435 CDS NP_688595.1 22537744 1014413 complement(1605683..1606372) 1 NC_004116.1 identified by match to PFAM protein family HMM PF01027; hypothetical protein 1606372 1014413 SAG1604 Streptococcus agalactiae 2603V/R hypothetical protein NP_688595.1 1605683 R 208435 CDS NP_688596.1 22537745 1014414 complement(1606395..1606898) 1 NC_004116.1 hypothetical protein 1606898 1014414 SAG1605 Streptococcus agalactiae 2603V/R hypothetical protein NP_688596.1 1606395 R 208435 CDS NP_688597.1 22537746 1014415 complement(1606936..1607679) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00588; RNA methyltransferase 1607679 1014415 SAG1606 Streptococcus agalactiae 2603V/R RNA methyltransferase NP_688597.1 1606936 R 208435 CDS NP_688598.1 22537747 1014416 1607711..1607989 1 NC_004116.1 catalyzes the hydrolysis of acylphosphate; acylphosphatase 1607989 1014416 SAG1607 Streptococcus agalactiae 2603V/R acylphosphatase NP_688598.1 1607711 D 208435 CDS NP_688599.1 22537748 1014417 1608074..1609006 1 NC_004116.1 involved in biogenesis of membrane proteins; Firmicutes specific proteins are shorter than other bacterial counterparts and have a signal peptide and lipid attachment site; OxaA-like protein precursor 1609006 1014417 SAG1608 Streptococcus agalactiae 2603V/R OxaA-like protein precursor NP_688599.1 1608074 D 208435 CDS NP_688600.1 22537749 1014418 complement(1609206..1609871) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00528; amino acid ABC transporter permease 1609871 1014418 SAG1609 Streptococcus agalactiae 2603V/R amino acid ABC transporter permease NP_688600.1 1609206 R 208435 CDS NP_688601.1 22537750 1014419 complement(1609895..1610752) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00497; amino acid ABC transporter substrate-binding protein 1610752 1014419 SAG1610 Streptococcus agalactiae 2603V/R amino acid ABC transporter substrate-binding protein NP_688601.1 1609895 R 208435 CDS NP_688602.1 22537751 1014420 complement(1610913..1612373) 1 NC_004116.1 catalyzes the hydrolysis of a monocarboxylic acid amid to form a monocarboxylate and ammonia; amidase 1612373 1014420 SAG1611 Streptococcus agalactiae 2603V/R amidase NP_688602.1 1610913 R 208435 CDS NP_688603.1 22537752 1014421 complement(1612476..1612958) 1 NC_004116.1 necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus; transcription elongation factor GreA 1612958 greA 1014421 greA Streptococcus agalactiae 2603V/R transcription elongation factor GreA NP_688603.1 1612476 R 208435 CDS NP_688604.1 22537753 1014422 complement(1613031..1614833) 1 NC_004116.1 hypothetical protein 1614833 1014422 SAG1613 Streptococcus agalactiae 2603V/R hypothetical protein NP_688604.1 1613031 R 208435 CDS NP_688605.1 22537754 1014423 complement(1614920..1615423) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00583; acetyltransferase 1615423 1014423 SAG1614 Streptococcus agalactiae 2603V/R acetyltransferase NP_688605.1 1614920 R 208435 CDS NP_688606.1 22537755 1014424 complement(1615509..1616840) 1 NC_004116.1 Catalyzes the formation of UDP-N-acetylmuramoyl-L-alanine from UDP-N-acetylmuramate and L-alanine in peptidoglycan synthesis; UDP-N-acetylmuramate--L-alanine ligase 1616840 murC 1014424 murC Streptococcus agalactiae 2603V/R UDP-N-acetylmuramate--L-alanine ligase NP_688606.1 1615509 R 208435 CDS NP_688607.1 22537756 1014425 complement(1616850..1617467) 1 NC_004116.1 hypothetical protein 1617467 1014425 SAG1616 Streptococcus agalactiae 2603V/R hypothetical protein NP_688607.1 1616850 R 208435 CDS NP_688608.1 22537757 1014426 complement(1617472..1617570) 1 NC_004116.1 hypothetical protein 1617570 1014426 SAG1617 Streptococcus agalactiae 2603V/R hypothetical protein NP_688608.1 1617472 R 208435 CDS NP_688609.1 22537758 1014427 complement(1617632..1620730) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00176; The product of this gene was detected by Western blot analysis. For details on the method see Tettelin et al. 2002.; Snf2 family protein 1620730 1014427 SAG1618 Streptococcus agalactiae 2603V/R Snf2 family protein NP_688609.1 1617632 R 208435 CDS NP_688610.1 22537759 1014428 complement(1620893..1622026) 1 NC_004116.1 identified by match to PFAM protein family HMM PF01609; IS1548 transposase 1622026 1014428 SAG1619 Streptococcus agalactiae 2603V/R IS1548 transposase NP_688610.1 1620893 R 208435 CDS NP_688611.1 22537760 1014429 complement(1622211..1623521) 1 NC_004116.1 EngA; essential Neisserial GTPase; synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains; GTP-binding protein EngA 1623521 engA 1014429 engA Streptococcus agalactiae 2603V/R GTP-binding protein EngA NP_688611.1 1622211 R 208435 CDS NP_688612.1 22537761 1014430 complement(1623569..1624471) 1 NC_004116.1 Primosomal protein that may act to load helicase DnaC during DNA replication; primosomal protein DnaI 1624471 dnaI 1014430 dnaI Streptococcus agalactiae 2603V/R primosomal protein DnaI NP_688612.1 1623569 R 208435 CDS NP_688613.1 22537762 1014431 complement(1624468..1625643) 1 NC_004116.1 hypothetical protein 1625643 1014431 SAG1622 Streptococcus agalactiae 2603V/R hypothetical protein NP_688613.1 1624468 R 208435 CDS NP_688614.1 22537763 1014432 complement(1625643..1626122) 1 NC_004116.1 NrdR family transcriptional regulator 1626122 nrdR 1014432 nrdR Streptococcus agalactiae 2603V/R NrdR family transcriptional regulator NP_688614.1 1625643 R 208435 CDS NP_688615.1 22537764 1014433 complement(1626271..1627776) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00512; sensor histidine kinase CsrS 1627776 csrS 1014433 csrS Streptococcus agalactiae 2603V/R sensor histidine kinase CsrS NP_688615.1 1626271 R 208435 CDS NP_688616.1 22537765 1014434 complement(1627766..1628455) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00072; DNA-binding response regulator CsrR 1628455 csrR 1014434 csrR Streptococcus agalactiae 2603V/R DNA-binding response regulator CsrR NP_688616.1 1627766 R 208435 CDS NP_688617.1 22537766 1014435 complement(1628690..1629223) 1 NC_004116.1 hypothetical protein 1629223 1014435 SAG1626 Streptococcus agalactiae 2603V/R hypothetical protein NP_688617.1 1628690 R 208435 CDS NP_688618.1 22537767 1014436 complement(1629328..1630218) 1 NC_004116.1 metalloprotease; heat shock protein HtpX 1630218 htpX 1014436 htpX Streptococcus agalactiae 2603V/R heat shock protein HtpX NP_688618.1 1629328 R 208435 CDS NP_688619.1 22537768 1014437 complement(1630239..1630793) 1 NC_004116.1 similar to OMNI:SP1284; identified by sequence similarity; hypothetical protein 1630793 lemA 1014437 lemA Streptococcus agalactiae 2603V/R hypothetical protein NP_688619.1 1630239 R 208435 CDS NP_688620.1 22537769 1014438 1630921..1631634 1 NC_004116.1 glucose-inhibited division protein B; SAM-dependent methyltransferase; methylates the N7 position of guanosine in position 527 of 16S rRNA; 16S rRNA methyltransferase GidB 1631634 gidB 1014438 gidB Streptococcus agalactiae 2603V/R 16S rRNA methyltransferase GidB NP_688620.1 1630921 D 208435 CDS NP_688621.1 22537770 1014439 1631649..1633028 1 NC_004116.1 identified by match to PFAM protein family HMM PF02386; sodium transport family protein 1633028 1014439 SAG1630 Streptococcus agalactiae 2603V/R sodium transport family protein NP_688621.1 1631649 D 208435 CDS NP_688622.1 22537771 1014440 1633041..1633712 1 NC_004116.1 identified by match to PFAM protein family HMM PF02254; Trk family potassium uptake protein 1633712 1014440 SAG1631 Streptococcus agalactiae 2603V/R Trk family potassium uptake protein NP_688622.1 1633041 D 208435 CDS NP_688623.1 22537772 1014441 complement(1633747..1634577) 1 NC_004116.1 identified by match to PFAM protein family HMM PF02361; cobalt transport family protein 1634577 1014441 SAG1632 Streptococcus agalactiae 2603V/R cobalt transport family protein NP_688623.1 1633747 R 208435 CDS NP_688624.1 22537773 1014442 complement(1634570..1636246) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00005; ABC transporter ATP-binding protein 1636246 1014442 SAG1633 Streptococcus agalactiae 2603V/R ABC transporter ATP-binding protein NP_688624.1 1634570 R 208435 CDS NP_688625.2 545902390 1014443 complement(1636263..1636811) 1 NC_004116.1 hypothetical protein 1636811 1014443 SAG1634 Streptococcus agalactiae 2603V/R hypothetical protein NP_688625.2 1636263 R 208435 CDS NP_688626.1 22537775 1014444 complement(1636980..1638188) 1 NC_004116.1 involved in the import of serine and threonine coupled with the import of sodium; serine/threonine transporter SstT 1638188 1014444 SAG1635 Streptococcus agalactiae 2603V/R serine/threonine transporter SstT NP_688626.1 1636980 R 208435 CDS NP_688627.1 22537776 1014445 1638364..1639731 1 NC_004116.1 identified by match to TIGR protein family HMM TIGR00796; branched-chain amino acid transport system II carrier protein 1639731 brnQ-2 1014445 brnQ-2 Streptococcus agalactiae 2603V/R branched-chain amino acid transport system II carrier protein NP_688627.1 1638364 D 208435 CDS NP_688628.1 22537777 1014446 1639845..1640900 1 NC_004116.1 identified by match to PFAM protein family HMM PF00107; zinc-containing alcohol dehydrogenase 1640900 adh 1014446 adh Streptococcus agalactiae 2603V/R zinc-containing alcohol dehydrogenase NP_688628.1 1639845 D 208435 CDS NP_688629.1 22537778 1014447 complement(1640949..1641641) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00528; ABC transporter permease 1641641 1014447 SAG1638 Streptococcus agalactiae 2603V/R ABC transporter permease NP_688629.1 1640949 R 208435 CDS NP_688630.1 22537779 1014448 complement(1641638..1642708) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00005; ABC transporter ATP-binding protein 1642708 1014448 SAG1639 Streptococcus agalactiae 2603V/R ABC transporter ATP-binding protein NP_688630.1 1641638 R 208435 CDS NP_688631.1 22537780 1014449 complement(1642701..1644077) 1 NC_004116.1 identified by match to PFAM protein family HMM PF01546; hypothetical protein 1644077 1014449 SAG1640 Streptococcus agalactiae 2603V/R hypothetical protein NP_688631.1 1642701 R 208435 CDS NP_688632.1 22537781 1014450 complement(1644211..1645035) 1 NC_004116.1 identified by match to PFAM protein family HMM PF03180; The product of this gene was detected by Western blot analysis. For details on the method see Tettelin et al. 2002.; YaeC family protein 1645035 1014450 SAG1641 Streptococcus agalactiae 2603V/R YaeC family protein NP_688632.1 1644211 R 208435 CDS NP_688633.1 22537782 1014451 complement(1645176..1646009) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00497; ABC transporter substrate-binding protein 1646009 1014451 SAG1642 Streptococcus agalactiae 2603V/R ABC transporter substrate-binding protein NP_688633.1 1645176 R 208435 CDS NP_688634.1 22537783 1014452 complement(1646111..1646800) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00117; glutamine amidotransferase 1646800 1014452 SAG1643 Streptococcus agalactiae 2603V/R glutamine amidotransferase NP_688634.1 1646111 R 208435 CDS NP_688635.1 22537784 1014453 complement(1646794..1646907) 1 NC_004116.1 hypothetical protein 1646907 1014453 SAG1644 Streptococcus agalactiae 2603V/R hypothetical protein NP_688635.1 1646794 R 208435 CDS NP_688636.1 22537785 1014454 complement(1646955..1647671) 1 NC_004116.1 hypothetical protein 1647671 1014454 SAG1645 Streptococcus agalactiae 2603V/R hypothetical protein NP_688636.1 1646955 R 208435 CDS NP_688637.1 22537786 1014455 complement(1647697..1647795) 1 NC_004116.1 hypothetical protein 1647795 1014455 SAG1646 Streptococcus agalactiae 2603V/R hypothetical protein NP_688637.1 1647697 R 208435 CDS NP_688638.1 22537787 1014456 complement(1647789..1648775) 1 NC_004116.1 similar to DhaK; in Lactococcus lactis this protein froms a stable complex with DhaS and activates transcription of the dha operon in the presence of dihydroxyacetone; DhaKLM operon coactivator DhaQ 1648775 1014456 SAG1647 Streptococcus agalactiae 2603V/R DhaKLM operon coactivator DhaQ NP_688638.1 1647789 R 208435 CDS NP_688639.1 22537788 1014457 complement(1648785..1649321) 1 NC_004116.1 TetR family transcriptional regulator 1649321 1014457 SAG1648 Streptococcus agalactiae 2603V/R TetR family transcriptional regulator NP_688639.1 1648785 R 208435 CDS NP_688640.1 22537789 1014458 1649385..1649498 1 NC_004116.1 hypothetical protein 1649498 1014458 SAG1649 Streptococcus agalactiae 2603V/R hypothetical protein NP_688640.1 1649385 D 208435 CDS NP_688641.1 22537790 1014459 1649495..1650484 1 NC_004116.1 with DhaL and DhaM forms dihydroxyacetone kinase, which is responsible for phosphorylating dihydroxyacetone; DhaK is the dihydroxyacetone binding subunit of the dihydroxyacetone kinase; dihydroxyacetone kinase subunit DhaK 1650484 1014459 SAG1650 Streptococcus agalactiae 2603V/R dihydroxyacetone kinase subunit DhaK NP_688641.1 1649495 D 208435 CDS NP_688642.1 22537791 1014460 1650522..1651100 1 NC_004116.1 identified by match to PFAM protein family HMM PF02734; dihydroxyacetone kinase family protein 1651100 1014460 SAG1651 Streptococcus agalactiae 2603V/R dihydroxyacetone kinase family protein NP_688642.1 1650522 D 208435 CDS NP_688643.1 22537792 1014461 1651100..1651474 1 NC_004116.1 PTS system mannnose-specific transporter subunit IIA 1651474 1014461 SAG1652 Streptococcus agalactiae 2603V/R PTS system mannnose-specific transporter subunit IIA NP_688643.1 1651100 D 208435 CDS NP_688644.1 22537793 1014462 1651484..1652197 1 NC_004116.1 identified by match to PFAM protein family HMM PF00230; glycerol uptake facilitator protein 1652197 glpF-2 1014462 glpF-2 Streptococcus agalactiae 2603V/R glycerol uptake facilitator protein NP_688644.1 1651484 D 208435 CDS NP_688645.1 22537794 1014463 complement(1652462..1652866) 1 NC_004116.1 hypothetical protein 1652866 1014463 SAG1654 Streptococcus agalactiae 2603V/R hypothetical protein NP_688645.1 1652462 R 208435 CDS NP_688646.1 22537795 1014464 complement(1653005..1653718) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00376; MerR family transcriptional regulator 1653718 1014464 SAG1655 Streptococcus agalactiae 2603V/R MerR family transcriptional regulator NP_688646.1 1653005 R 208435 CDS NP_688647.1 22537796 1014465 complement(1653811..1654920) 1 NC_004116.1 hypothetical protein 1654920 1014465 SAG1656 Streptococcus agalactiae 2603V/R hypothetical protein NP_688647.1 1653811 R 208435 CDS NP_688648.1 22537797 1014466 complement(1654917..1655168) 1 NC_004116.1 hypothetical protein 1655168 1014466 SAG1657 Streptococcus agalactiae 2603V/R hypothetical protein NP_688648.1 1654917 R 208435 CDS NP_688649.1 22537798 1014467 complement(1655191..1655925) 1 NC_004116.1 hypothetical protein 1655925 1014467 SAG1658 Streptococcus agalactiae 2603V/R hypothetical protein NP_688649.1 1655191 R 208435 CDS NP_688650.1 22537799 1014468 complement(1655991..1656347) 1 NC_004116.1 identified by match to PFAM protein family HMM PF02410; iojap-like protein 1656347 1014468 SAG1659 Streptococcus agalactiae 2603V/R iojap-like protein NP_688650.1 1655991 R 208435 CDS NP_688651.1 22537800 1014469 complement(1656349..1656870) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00857; isochorismatase family protein 1656870 1014469 SAG1660 Streptococcus agalactiae 2603V/R isochorismatase family protein NP_688651.1 1656349 R 208435 CDS NP_688652.1 22537801 1014470 complement(1656933..1657520) 1 NC_004116.1 hypothetical protein 1657520 1014470 SAG1661 Streptococcus agalactiae 2603V/R hypothetical protein NP_688652.1 1656933 R 208435 CDS NP_688653.1 22537802 1014471 complement(1657517..1658149) 1 NC_004116.1 transfers an adenyl group from ATP to NaMN to form nicotinic acid adenine dinucleotide (NaAD) which is then converted to the ubiquitous compound NAD by NAD synthetase; essential enzyme in bacteria; nicotinic acid mononucleotide adenylyltransferase 1658149 nadD 1014471 nadD Streptococcus agalactiae 2603V/R nicotinic acid mononucleotide adenylyltransferase NP_688653.1 1657517 R 208435 CDS NP_688654.1 22537803 1014472 complement(1658279..1658596) 1 NC_004116.1 hypothetical protein 1658596 1014472 SAG1663 Streptococcus agalactiae 2603V/R hypothetical protein NP_688654.1 1658279 R 208435 CDS NP_688655.1 22537804 1014473 complement(1658689..1659807) 1 NC_004116.1 in Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis; GTP-binding protein YqeH 1659807 1014473 SAG1664 Streptococcus agalactiae 2603V/R GTP-binding protein YqeH NP_688655.1 1658689 R 208435 CDS NP_688656.1 22537805 1014474 complement(1659807..1660340) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00702; HAD superfamily hydrolase 1660340 1014474 SAG1665 Streptococcus agalactiae 2603V/R HAD superfamily hydrolase NP_688656.1 1659807 R 208435 CDS NP_688657.1 22537806 1014475 complement(1660451..1661365) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00892; hypothetical protein 1661365 1014475 SAG1666 Streptococcus agalactiae 2603V/R hypothetical protein NP_688657.1 1660451 R 208435 CDS NP_688658.1 22537807 1014476 complement(1661495..1662937) 1 NC_004116.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; aspartyl/glutamyl-tRNA amidotransferase subunit B 1662937 gatB 1014476 gatB Streptococcus agalactiae 2603V/R aspartyl/glutamyl-tRNA amidotransferase subunit B NP_688658.1 1661495 R 208435 CDS NP_688659.1 22537808 1014477 complement(1662937..1664403) 1 NC_004116.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; aspartyl/glutamyl-tRNA amidotransferase subunit A 1664403 gatA 1014477 gatA Streptococcus agalactiae 2603V/R aspartyl/glutamyl-tRNA amidotransferase subunit A NP_688659.1 1662937 R 208435 CDS NP_688660.1 22537809 1014478 complement(1664403..1664705) 1 NC_004116.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; some Mycoplasma proteins contain an N-terminal fusion to an unknown domain; aspartyl/glutamyl-tRNA amidotransferase subunit C 1664705 gatC 1014478 gatC Streptococcus agalactiae 2603V/R aspartyl/glutamyl-tRNA amidotransferase subunit C NP_688660.1 1664403 R 208435 CDS NP_688661.1 22537810 1014479 complement(1664843..1667488) 1 NC_004116.1 catalyzes the formation of phosphoenolpyruvate from pyruvate; pyruvate phosphate dikinase 1667488 ppdK 1014479 ppdK Streptococcus agalactiae 2603V/R pyruvate phosphate dikinase NP_688661.1 1664843 R 208435 CDS NP_688662.1 22537811 1014480 complement(1667501..1668331) 1 NC_004116.1 similar to OMNI:NTL01BH1376; identified by sequence similarity; The product of this gene was detected by Western blot analysis. For details on the method see Tettelin et al. 2002.; hypothetical protein 1668331 1014480 SAG1671 Streptococcus agalactiae 2603V/R hypothetical protein NP_688662.1 1667501 R 208435 CDS NP_688663.1 22537812 1014481 complement(1668342..1668854) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00571; In pairwise matches, the initiation methionine is located 40 residues upstream from the current start site of this gene; although there is strong sequence similarity, this ORF lacks an initiation codon in that upstream region.; hypothetical protein 1668854 1014481 SAG1672 Streptococcus agalactiae 2603V/R hypothetical protein NP_688663.1 1668342 R 208435 CDS NP_688664.1 22537813 1014482 1669160..1670125 1 NC_004116.1 converts (S)-3-hydroxybutanoyl-CoA to 3-acetoacetyl-CoA; 3-hydroxybutyryl-CoA dehydrogenase 1670125 1014482 SAG1673 Streptococcus agalactiae 2603V/R 3-hydroxybutyryl-CoA dehydrogenase NP_688664.1 1669160 D 208435 CDS NP_688665.1 22537814 1014483 complement(1670172..1670720) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00857; isochorismatase family protein 1670720 1014483 SAG1674 Streptococcus agalactiae 2603V/R isochorismatase family protein NP_688665.1 1670172 R 208435 CDS NP_688666.1 22537815 1014484 complement(1670787..1671572) 1 NC_004116.1 CodY; DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase (By similarity). It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor; transcriptional repressor CodY 1671572 1014484 SAG1675 Streptococcus agalactiae 2603V/R transcriptional repressor CodY NP_688666.1 1670787 R 208435 CDS NP_688667.1 22537816 1014485 complement(1671698..1672909) 1 NC_004116.1 broad specificity; family IV; in Corynebacterium glutamicum this protein can use glutamate, 2-aminobutyrate, and aspartate as amino donors and pyruvate as the acceptor; aminotransferase 1672909 1014485 SAG1676 Streptococcus agalactiae 2603V/R aminotransferase NP_688667.1 1671698 R 208435 CDS NP_688668.1 22537817 1014486 1673176..1673628 1 NC_004116.1 hypothetical protein 1673628 1014486 SAG1677 Streptococcus agalactiae 2603V/R hypothetical protein NP_688668.1 1673176 D 208435 CDS NP_688669.1 22537818 1014487 complement(1673684..1675066) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00702; HAD superfamily hydrolase 1675066 1014487 SAG1678 Streptococcus agalactiae 2603V/R HAD superfamily hydrolase NP_688669.1 1673684 R 208435 CDS NP_688670.1 22537819 1014488 1675135..1676097 1 NC_004116.1 identified by match to PFAM protein family HMM PF00710; asparaginase 1676097 1014488 SAG1679 Streptococcus agalactiae 2603V/R asparaginase NP_688670.1 1675135 D 208435 CDS NP_688671.1 22537820 1014489 complement(1676132..1677010) 1 NC_004116.1 identified by match to PFAM protein family HMM PF01488; shikimate 5-dehydrogenase 1677010 aroE 1014489 aroE Streptococcus agalactiae 2603V/R shikimate 5-dehydrogenase NP_688671.1 1676132 R 208435 CDS NP_688672.1 22537821 1014490 complement(1677108..1678022) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00248; aldo/keto reductase 1678022 1014490 SAG1681 Streptococcus agalactiae 2603V/R aldo/keto reductase NP_688672.1 1677108 R 208435 CDS NP_688673.1 22537822 1014491 complement(1678313..1680328) 1 NC_004116.1 catalyzes branch migration in Holliday junction intermediates; ATP-dependent DNA helicase RecG 1680328 recG 1014491 recG Streptococcus agalactiae 2603V/R ATP-dependent DNA helicase RecG NP_688673.1 1678313 R 208435 CDS NP_688674.1 22537823 1014492 complement(1680408..1681946) 1 NC_004116.1 similar to GP:1399011; identified by sequence similarity; hypothetical protein 1681946 1014492 SAG1683 Streptococcus agalactiae 2603V/R hypothetical protein NP_688674.1 1680408 R 208435 CDS NP_688675.1 22537824 1014493 complement(1682039..1683139) 1 NC_004116.1 converts L-alanine to D-alanine which is used in cell wall biosynthesis; binds one pyridoxal phosphate per monomer; forms a homodimer; alanine racemase 1683139 alr 1014493 alr Streptococcus agalactiae 2603V/R alanine racemase NP_688675.1 1682039 R 208435 CDS NP_688676.1 22537825 1014494 complement(1683136..1683495) 1 NC_004116.1 Catalyzes the formation of holo-ACP, which mediates the essential transfer of acyl fatty acid intermediates during the biosynthesis of fatty acids and lipids; 4'-phosphopantetheinyl transferase 1683495 acpS 1014494 acpS Streptococcus agalactiae 2603V/R 4'-phosphopantetheinyl transferase NP_688676.1 1683136 R 208435 CDS NP_688677.1 22537826 1014495 complement(1683520..1684527) 1 NC_004116.1 catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, phenylalanine sensitive; phospho-2-dehydro-3-deoxyheptonate aldolase 1684527 1014495 SAG1686 Streptococcus agalactiae 2603V/R phospho-2-dehydro-3-deoxyheptonate aldolase NP_688677.1 1683520 R 208435 CDS NP_688678.1 22537827 1014496 complement(1684653..1687181) 1 NC_004116.1 functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond SecA1; SecA2 is not essential and seems to play a role in secretion of a subset of proteins; preprotein translocase subunit SecA 1687181 secA 1014496 secA Streptococcus agalactiae 2603V/R preprotein translocase subunit SecA NP_688678.1 1684653 R 208435 CDS NP_688679.1 22537828 1014497 complement(1687290..1688237) 1 NC_004116.1 identified by match to PFAM protein family HMM PF01238; mannose-6-phosphate isomerase 1688237 manA 1014497 manA Streptococcus agalactiae 2603V/R mannose-6-phosphate isomerase NP_688679.1 1687290 R 208435 CDS NP_688680.1 22537829 1014498 complement(1688355..1689236) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00480; fructokinase 1689236 scrK 1014498 scrK Streptococcus agalactiae 2603V/R fructokinase NP_688680.1 1688355 R 208435 CDS NP_688681.1 22537830 1014499 complement(1689304..1691223) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00358; PTS system transporter subunit IIABC 1691223 1014499 SAG1690 Streptococcus agalactiae 2603V/R PTS system transporter subunit IIABC NP_688681.1 1689304 R 208435 CDS NP_688682.1 22537831 1014500 1691408..1692847 1 NC_004116.1 identified by match to PFAM protein family HMM PF00251; sucrose-6-phosphate hydrolase 1692847 scrB 1014500 scrB Streptococcus agalactiae 2603V/R sucrose-6-phosphate hydrolase NP_688682.1 1691408 D 208435 CDS NP_688683.1 22537832 1014501 1692849..1693811 1 NC_004116.1 identified by match to PFAM protein family HMM PF00356; sucrose operon repressor ScrR 1693811 scrR 1014501 scrR Streptococcus agalactiae 2603V/R sucrose operon repressor ScrR NP_688683.1 1692849 D 208435 CDS NP_688684.1 22537833 1014502 complement(1693898..1694332) 1 NC_004116.1 Regulates rRNA biosynthesis by transcriptional antitermination; transcription antitermination protein NusB 1694332 nusB 1014502 nusB Streptococcus agalactiae 2603V/R transcription antitermination protein NusB NP_688684.1 1693898 R 208435 CDS NP_688685.1 22537834 1014503 complement(1694325..1694714) 1 NC_004116.1 hypothetical protein 1694714 1014503 SAG1694 Streptococcus agalactiae 2603V/R hypothetical protein NP_688685.1 1694325 R 208435 CDS NP_688686.1 22537835 1014504 complement(1694803..1695363) 1 NC_004116.1 Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA; elongation factor P 1695363 efp 1014504 efp Streptococcus agalactiae 2603V/R elongation factor P NP_688686.1 1694803 R 208435 CDS NP_688687.1 22537836 1014505 complement(1695394..1695510) 1 NC_004116.1 hypothetical protein 1695510 1014505 SAG1696 Streptococcus agalactiae 2603V/R hypothetical protein NP_688687.1 1695394 R 208435 CDS NP_688688.1 22537837 1014506 complement(1696092..1696238) 1 NC_004116.1 hypothetical protein 1696238 1014506 SAG1697 Streptococcus agalactiae 2603V/R hypothetical protein NP_688688.1 1696092 R 208435 CDS NP_688689.1 22537838 1014507 complement(1696291..1696590) 1 NC_004116.1 hypothetical protein 1696590 1014507 SAG1698 Streptococcus agalactiae 2603V/R hypothetical protein NP_688689.1 1696291 R 208435 CDS NP_688690.1 22537839 1014508 complement(1696643..1696735) 1 NC_004116.1 hypothetical protein 1696735 1014508 SAG1699 Streptococcus agalactiae 2603V/R hypothetical protein NP_688690.1 1696643 R 208435 CDS NP_688691.1 22537840 1014509 complement(1697008..1697238) 1 NC_004116.1 hypothetical protein 1697238 1014509 SAG1700 Streptococcus agalactiae 2603V/R hypothetical protein NP_688691.1 1697008 R 208435 CDS NP_688692.1 22537841 1014510 complement(1697251..1697421) 1 NC_004116.1 hypothetical protein 1697421 1014510 SAG1701 Streptococcus agalactiae 2603V/R hypothetical protein NP_688692.1 1697251 R 208435 CDS NP_688693.1 22537842 1014511 complement(1697874..1697999) 1 NC_004116.1 hypothetical protein 1697999 1014511 SAG1702 Streptococcus agalactiae 2603V/R hypothetical protein NP_688693.1 1697874 R 208435 CDS NP_688694.1 22537843 1014512 complement(1698010..1698174) 1 NC_004116.1 hypothetical protein 1698174 1014512 SAG1703 Streptococcus agalactiae 2603V/R hypothetical protein NP_688694.1 1698010 R 208435 CDS NP_688695.1 22537844 1014513 complement(1698476..1698928) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00383; cytidine/deoxycytidylate deaminase family protein 1698928 1014513 SAG1704 Streptococcus agalactiae 2603V/R cytidine/deoxycytidylate deaminase family protein NP_688695.1 1698476 R 208435 CDS NP_688696.1 22537845 1014515 complement(1700107..1700823) 1 NC_004116.1 hypothetical protein 1700823 1014515 SAG1706 Streptococcus agalactiae 2603V/R hypothetical protein NP_688696.1 1700107 R 208435 CDS NP_688697.1 22537846 1014516 complement(1700825..1702324) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00083; EmrB/QacA family drug resistance transporter 1702324 1014516 SAG1707 Streptococcus agalactiae 2603V/R EmrB/QacA family drug resistance transporter NP_688697.1 1700825 R 208435 CDS NP_688698.1 22537847 1014517 complement(1702412..1702528) 1 NC_004116.1 hypothetical protein 1702528 1014517 SAG1708 Streptococcus agalactiae 2603V/R hypothetical protein NP_688698.1 1702412 R 208435 CDS NP_688699.1 22537848 1014518 complement(1702660..1705488) 1 NC_004116.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate; excinuclease ABC subunit A 1705488 uvrA 1014518 uvrA Streptococcus agalactiae 2603V/R excinuclease ABC subunit A NP_688699.1 1702660 R 208435 CDS NP_688700.1 22537849 1014519 complement(1705620..1706291) 1 NC_004116.1 hypothetical protein 1706291 1014519 SAG1710 Streptococcus agalactiae 2603V/R hypothetical protein NP_688700.1 1705620 R 208435 CDS NP_688701.1 22537850 1014520 complement(1706316..1707260) 1 NC_004116.1 identified by match to PFAM protein family HMM PF01544; magnesium transporter CorA family protein 1707260 1014520 SAG1711 Streptococcus agalactiae 2603V/R magnesium transporter CorA family protein NP_688701.1 1706316 R 208435 CDS NP_688702.1 22537851 1014521 complement(1707430..1707669) 1 NC_004116.1 binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit; 30S ribosomal protein S18 1707669 rpsR 1014521 rpsR Streptococcus agalactiae 2603V/R 30S ribosomal protein S18 NP_688702.1 1707430 R 208435 CDS NP_688703.1 22537852 1014522 complement(1707714..1708205) 1 NC_004116.1 binds to single stranded DNA and may facilitate the binding and interaction of other proteins to DNA; single-stranded DNA-binding protein 1708205 ssb-3 1014522 ssb-3 Streptococcus agalactiae 2603V/R single-stranded DNA-binding protein NP_688703.1 1707714 R 208435 CDS NP_688704.1 22537853 1014523 complement(1708217..1708504) 1 NC_004116.1 binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21; 30S ribosomal protein S6 1708504 rpsF 1014523 rpsF Streptococcus agalactiae 2603V/R 30S ribosomal protein S6 NP_688704.1 1708217 R 208435 CDS NP_688705.1 22537854 1014524 1709598..1710722 1 NC_004116.1 identified by match to PFAM protein family HMM PF00730; A/G-specific adenine glycosylase 1710722 mutY 1014524 mutY Streptococcus agalactiae 2603V/R A/G-specific adenine glycosylase NP_688705.1 1709598 D 208435 CDS NP_688706.1 22537855 1014525 1710899..1711492 1 NC_004116.1 identified by match to PFAM protein family HMM PF01381; Cro/CI family transcriptional regulator 1711492 1014525 SAG1716 Streptococcus agalactiae 2603V/R Cro/CI family transcriptional regulator NP_688706.1 1710899 D 208435 CDS NP_688707.1 22537856 1014526 complement(1711538..1711852) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00085; thioredoxin 1711852 trx 1014526 trx Streptococcus agalactiae 2603V/R thioredoxin NP_688707.1 1711538 R 208435 CDS NP_688708.1 22537857 1014527 complement(1711933..1712433) 1 NC_004116.1 identified by match to PFAM protein family HMM PF01569; PAP2 family protein 1712433 1014527 SAG1718 Streptococcus agalactiae 2603V/R PAP2 family protein NP_688708.1 1711933 R 208435 CDS NP_688709.1 22537858 1014528 complement(1712437..1714776) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00488; Function of MutS2 is unknown. It should not be considered a DNA mismatch repair protein. It is likely a DNA mismatch binding protein of unknown cellular function.; MutS2 family protein 1714776 1014528 SAG1719 Streptococcus agalactiae 2603V/R MutS2 family protein NP_688709.1 1712437 R 208435 CDS NP_688710.1 22537859 1014529 complement(1714861..1715403) 1 NC_004116.1 hypothetical protein 1715403 1014529 SAG1720 Streptococcus agalactiae 2603V/R hypothetical protein NP_688710.1 1714861 R 208435 CDS NP_688711.1 22537860 1014530 complement(1715406..1715717) 1 NC_004116.1 hypothetical protein 1715717 1014530 SAG1721 Streptococcus agalactiae 2603V/R hypothetical protein NP_688711.1 1715406 R 208435 CDS NP_688712.1 22537861 1014531 1715828..1716721 1 NC_004116.1 An endonuclease that specifically degrades the RNA strand of RNA-DNA hybrids; ribonuclease HIII 1716721 rnhC 1014531 rnhC Streptococcus agalactiae 2603V/R ribonuclease HIII NP_688712.1 1715828 D 208435 CDS NP_688713.1 22537862 1014532 1716737..1717330 1 NC_004116.1 identified by match to PFAM protein family HMM PF00461; signal peptidase I 1717330 1014532 SAG1723 Streptococcus agalactiae 2603V/R signal peptidase I NP_688713.1 1716737 D 208435 CDS NP_688714.1 22537863 1014533 1717459..1719879 1 NC_004116.1 identified by match to TIGR protein family HMM TIGR01448; helicase 1719879 1014533 SAG1724 Streptococcus agalactiae 2603V/R helicase NP_688714.1 1717459 D 208435 CDS NP_688715.1 22537864 1014534 1719993..1720475 1 NC_004116.1 hypothetical protein 1720475 1014534 SAG1725 Streptococcus agalactiae 2603V/R hypothetical protein NP_688715.1 1719993 D 208435 CDS NP_688716.1 22537865 1014535 complement(1720546..1721640) 1 NC_004116.1 involved in translesion DNA polymerization with beta clamp of polymerase III; belongs to Y family of polymerases; does not contain proofreading function; DNA polymerase IV 1721640 dinP 1014535 dinP Streptococcus agalactiae 2603V/R DNA polymerase IV NP_688716.1 1720546 R 208435 CDS NP_688717.1 22537866 1014536 1721825..1724137 1 NC_004116.1 identified by match to PFAM protein family HMM PF01228; formate acetyltransferase 1724137 pflD-2 1014536 pflD-2 Streptococcus agalactiae 2603V/R formate acetyltransferase NP_688717.1 1721825 D 208435 CDS NP_688718.1 22537867 1014537 1724238..1724612 1 NC_004116.1 similar to SP:Q46604; identified by sequence similarity; FMN-binding protein 1724612 1014537 SAG1728 Streptococcus agalactiae 2603V/R FMN-binding protein NP_688718.1 1724238 D 208435 CDS NP_688719.1 22537868 1014538 complement(1724647..1725576) 1 NC_004116.1 hypothetical protein 1725576 1014538 SAG1729 Streptococcus agalactiae 2603V/R hypothetical protein NP_688719.1 1724647 R 208435 CDS NP_688720.1 22537869 1014539 complement(1725573..1726328) 1 NC_004116.1 hypothetical protein 1726328 1014539 SAG1730 Streptococcus agalactiae 2603V/R hypothetical protein NP_688720.1 1725573 R 208435 CDS NP_688721.1 22537870 1014540 1726453..1727349 1 NC_004116.1 hypothetical protein 1727349 1014540 SAG1731 Streptococcus agalactiae 2603V/R hypothetical protein NP_688721.1 1726453 D 208435 CDS NP_688722.1 22537871 1014541 complement(1727428..1728276) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00230; glycerol uptake facilitator protein 1728276 1014541 SAG1732 Streptococcus agalactiae 2603V/R glycerol uptake facilitator protein NP_688722.1 1727428 R 208435 CDS NP_688723.1 22537872 1014542 complement(1728444..1728896) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00582; universal stress protein 1728896 1014542 SAG1733 Streptococcus agalactiae 2603V/R universal stress protein NP_688723.1 1728444 R 208435 CDS NP_688724.1 22537873 1014543 complement(1728914..1730116) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00083; transporter 1730116 1014543 SAG1734 Streptococcus agalactiae 2603V/R transporter NP_688724.1 1728914 R 208435 CDS NP_688725.1 22537874 1014544 1730273..1730932 1 NC_004116.1 Crp/Fnr family transcriptional regulator 1730932 1014544 SAG1735 Streptococcus agalactiae 2603V/R Crp/Fnr family transcriptional regulator NP_688725.1 1730273 D 208435 CDS NP_688726.1 22537875 1014545 1730956..1733241 1 NC_004116.1 catalyzes the removal of N-terminal dipeptides when proline is the penultimate residue; x-prolyl-dipeptidyl aminopeptidase 1733241 pepX 1014545 pepX Streptococcus agalactiae 2603V/R x-prolyl-dipeptidyl aminopeptidase NP_688726.1 1730956 D 208435 CDS NP_688727.1 22537876 1014546 1733245..1733604 1 NC_004116.1 hypothetical protein 1733604 1014546 SAG1737 Streptococcus agalactiae 2603V/R hypothetical protein NP_688727.1 1733245 D 208435 CDS NP_688728.1 22537877 1014547 1733650..1734630 1 NC_004116.1 identified by match to PFAM protein family HMM PF00348; polyprenyl synthetase 1734630 1014547 SAG1738 Streptococcus agalactiae 2603V/R polyprenyl synthetase NP_688728.1 1733650 D 208435 CDS NP_688729.1 22537878 1014548 complement(1734715..1736463) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00005; ABC transporter ATP-binding protein 1736463 cydC 1014548 cydC Streptococcus agalactiae 2603V/R ABC transporter ATP-binding protein NP_688729.1 1734715 R 208435 CDS NP_688730.1 22537879 1014549 complement(1736456..1738174) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00005; ABC transporter ATP-binding protein 1738174 1014549 SAG1740 Streptococcus agalactiae 2603V/R ABC transporter ATP-binding protein NP_688730.1 1736456 R 208435 CDS NP_688731.1 22537880 1014550 complement(1738174..1739193) 1 NC_004116.1 identified by match to PFAM protein family HMM PF02322; cytochrome d ubiquinol oxidase, subunit II 1739193 cydB 1014550 cydB Streptococcus agalactiae 2603V/R cytochrome d ubiquinol oxidase, subunit II NP_688731.1 1738174 R 208435 CDS NP_688732.1 22537881 1014551 complement(1739194..1740621) 1 NC_004116.1 identified by match to PFAM protein family HMM PF01654; cytochrome d oxidase subunit I 1740621 cydA 1014551 cydA Streptococcus agalactiae 2603V/R cytochrome d oxidase subunit I NP_688732.1 1739194 R 208435 CDS NP_688733.1 22537882 1014552 complement(1740724..1741932) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00070; pyridine nucleotide-disulfide oxidoreductase family protein 1741932 1014552 SAG1743 Streptococcus agalactiae 2603V/R pyridine nucleotide-disulfide oxidoreductase family protein NP_688733.1 1740724 R 208435 CDS NP_688734.1 22537883 1014553 complement(1741945..1742844) 1 NC_004116.1 catalyzes the formation of dimethylmenaquinone from 1,4-dihydroxy-2-naphthoate and octaprenyl diphosphate; 1,4-dihydroxy-2-naphthoate octaprenyltransferase 1742844 1014553 SAG1744 Streptococcus agalactiae 2603V/R 1,4-dihydroxy-2-naphthoate octaprenyltransferase NP_688734.1 1741945 R 208435 CDS NP_688735.1 22537884 1014554 complement(1743253..1743699) 1 NC_004116.1 hypothetical protein 1743699 1014554 SAG1745 Streptococcus agalactiae 2603V/R hypothetical protein NP_688735.1 1743253 R 208435 CDS NP_688736.1 22537885 1014555 complement(1744352..1744459) 1 NC_004116.1 hypothetical protein 1744459 1014555 SAG1746 Streptococcus agalactiae 2603V/R hypothetical protein NP_688736.1 1744352 R 208435 CDS NP_688737.1 22537886 1014556 1744582..1744881 1 NC_004116.1 hypothetical protein 1744881 1014556 SAG1747 Streptococcus agalactiae 2603V/R hypothetical protein NP_688737.1 1744582 D 208435 CDS NP_688738.1 22537887 1014557 1745041..1746231 1 NC_004116.1 identified by match to PFAM protein family HMM PF02353; cyclopropane-fatty-acyl-phospholipid synthase 1746231 cfa 1014557 cfa Streptococcus agalactiae 2603V/R cyclopropane-fatty-acyl-phospholipid synthase NP_688738.1 1745041 D 208435 CDS NP_688739.1 22537888 1014558 complement(1746301..1747026) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00376; MerR family transcriptional regulator 1747026 1014558 SAG1749 Streptococcus agalactiae 2603V/R MerR family transcriptional regulator NP_688739.1 1746301 R 208435 CDS NP_688740.1 22537889 1014559 complement(1747153..1747740) 1 NC_004116.1 3'-5' exonuclease of DNA polymerase III; DNA polymerase III subunit epsilon 1747740 1014559 SAG1750 Streptococcus agalactiae 2603V/R DNA polymerase III subunit epsilon NP_688740.1 1747153 R 208435 CDS NP_688741.1 22537890 1014560 complement(1747784..1748320) 1 NC_004116.1 hypothetical protein 1748320 1014560 SAG1751 Streptococcus agalactiae 2603V/R hypothetical protein NP_688741.1 1747784 R 208435 CDS NP_688742.1 22537891 1014561 1748455..1749627 1 NC_004116.1 hypothetical protein 1749627 1014561 SAG1752 Streptococcus agalactiae 2603V/R hypothetical protein NP_688742.1 1748455 D 208435 CDS NP_688743.1 22537892 1014562 complement(1749671..1750453) 1 NC_004116.1 hypothetical protein 1750453 1014562 SAG1753 Streptococcus agalactiae 2603V/R hypothetical protein NP_688743.1 1749671 R 208435 CDS NP_688744.1 22537893 1014563 1750612..1750881 1 NC_004116.1 located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group do not appear to have the zinc-binding motif; 30S ribosomal protein S14 1750881 rpsN 1014563 rpsN Streptococcus agalactiae 2603V/R 30S ribosomal protein S14 NP_688744.1 1750612 D 208435 CDS NP_688745.1 22537894 1014564 1751089..1751205 1 NC_004116.1 hypothetical protein 1751205 1014564 SAG1755 Streptococcus agalactiae 2603V/R hypothetical protein NP_688745.1 1751089 D 208435 CDS NP_688746.1 22537895 1014565 complement(1751242..1752267) 1 NC_004116.1 hypothetical protein 1752267 1014565 SAG1756 Streptococcus agalactiae 2603V/R hypothetical protein NP_688746.1 1751242 R 208435 CDS NP_688747.1 22537896 1014566 complement(1752387..1753397) 1 NC_004116.1 in most organisms, only the N-terminal domain is present in a single polypeptide; in some archaea this domain is fused to a kinase domain; this gene is essential for growth in Escherichia coli and Bacillus subtilis; the secreted glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins; the Pyrococcus structure shows DNA-binding properties, iron-binding, ATP-binding, and AP endonuclease activity; DNA-binding/iron metalloprotein/AP endonuclease 1753397 1014566 SAG1757 Streptococcus agalactiae 2603V/R DNA-binding/iron metalloprotein/AP endonuclease NP_688747.1 1752387 R 208435 CDS NP_688748.1 22537897 1014567 complement(1753473..1753880) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00583; ribosomal-protein-alanine acetyltransferase 1753880 1014567 SAG1758 Streptococcus agalactiae 2603V/R ribosomal-protein-alanine acetyltransferase NP_688748.1 1753473 R 208435 CDS NP_688749.1 22537898 1014568 complement(1753882..1754574) 1 NC_004116.1 The product of this gene was detected by Western blot analysis. For details on the method see Tettelin et al. 2002.; hypothetical protein 1754574 1014568 SAG1759 Streptococcus agalactiae 2603V/R hypothetical protein NP_688749.1 1753882 R 208435 CDS NP_688750.1 22537899 1014569 1754753..1754983 1 NC_004116.1 hypothetical protein 1754983 1014569 SAG1760 Streptococcus agalactiae 2603V/R hypothetical protein NP_688750.1 1754753 D 208435 CDS NP_688751.1 22537900 1014570 1755037..1756716 1 NC_004116.1 identified by match to PFAM protein family HMM PF00753; metallo-beta-lactamase superfamily protein 1756716 1014570 SAG1761 Streptococcus agalactiae 2603V/R metallo-beta-lactamase superfamily protein NP_688751.1 1755037 D 208435 CDS NP_688752.1 22537901 1014571 complement(1756874..1757383) 1 NC_004116.1 hypothetical protein 1757383 1014571 SAG1762 Streptococcus agalactiae 2603V/R hypothetical protein NP_688752.1 1756874 R 208435 CDS NP_688753.1 22537902 1014572 complement(1757531..1758877) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00120; glutamine synthetase, type I 1758877 glnA 1014572 glnA Streptococcus agalactiae 2603V/R glutamine synthetase, type I NP_688753.1 1757531 R 208435 CDS NP_688754.1 22537903 1014573 complement(1758911..1759282) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00376; GlnR family transcriptional regulator 1759282 glnR 1014573 glnR Streptococcus agalactiae 2603V/R GlnR family transcriptional regulator NP_688754.1 1758911 R 208435 CDS NP_688755.1 22537904 1014574 complement(1759362..1759901) 1 NC_004116.1 hypothetical protein 1759901 1014574 SAG1765 Streptococcus agalactiae 2603V/R hypothetical protein NP_688755.1 1759362 R 208435 CDS NP_688756.1 22537905 1014575 complement(1760164..1761360) 1 NC_004116.1 Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway; phosphoglycerate kinase 1761360 pgk 1014575 pgk Streptococcus agalactiae 2603V/R phosphoglycerate kinase NP_688756.1 1760164 R 208435 CDS NP_688757.1 22537906 1014576 complement(1761495..1762364) 1 NC_004116.1 similar to GP:1944618; identified by sequence similarity; acid phosphatase 1762364 1014576 SAG1767 Streptococcus agalactiae 2603V/R acid phosphatase NP_688757.1 1761495 R 208435 CDS NP_688758.1 22537907 1014577 complement(1762573..1763583) 1 NC_004116.1 catalyzes the formation of 3-phospho-D-glyceroyl phosphate from D-glyceraldehyde 3-phosphate; glyceraldehyde-3-phosphate dehydrogenase 1763583 gap 1014577 gap Streptococcus agalactiae 2603V/R glyceraldehyde-3-phosphate dehydrogenase NP_688758.1 1762573 R 208435 CDS NP_688759.1 22537908 1014578 complement(1763787..1765865) 1 NC_004116.1 EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene; elongation factor G 1765865 fusA 1014578 fusA Streptococcus agalactiae 2603V/R elongation factor G NP_688759.1 1763787 R 208435 CDS NP_688760.1 22537909 1014579 complement(1766020..1766490) 1 NC_004116.1 binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit; 30S ribosomal protein S7 1766490 rpsG 1014579 rpsG Streptococcus agalactiae 2603V/R 30S ribosomal protein S7 NP_688760.1 1766020 R 208435 CDS NP_688761.1 22537910 1014580 complement(1766512..1766925) 1 NC_004116.1 interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance; 30S ribosomal protein S12 1766925 rpsL 1014580 rpsL Streptococcus agalactiae 2603V/R 30S ribosomal protein S12 NP_688761.1 1766512 R 208435 CDS NP_688762.1 22537911 1014581 complement(1767144..1767956) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00156; pur operon repressor 1767956 purR 1014581 purR Streptococcus agalactiae 2603V/R pur operon repressor NP_688762.1 1767144 R 208435 CDS NP_688763.1 22537912 1014582 complement(1768053..1768994) 1 NC_004116.1 identified by match to PFAM protein family HMM PF01966; HD domain-containing protein 1768994 1014582 SAG1773 Streptococcus agalactiae 2603V/R HD domain-containing protein NP_688763.1 1768053 R 208435 CDS NP_688764.1 22537913 1014583 complement(1768984..1770258) 1 NC_004116.1 hypothetical protein 1770258 1014583 SAG1774 Streptococcus agalactiae 2603V/R hypothetical protein NP_688764.1 1768984 R 208435 CDS NP_688765.1 22537914 1014584 complement(1770260..1770892) 1 NC_004116.1 hypothetical protein 1770892 1014584 SAG1775 Streptococcus agalactiae 2603V/R hypothetical protein NP_688765.1 1770260 R 208435 CDS NP_688766.1 22537915 1014585 complement(1770885..1771547) 1 NC_004116.1 catalyzes the interconversion of D-ribulose 5-phosphate to xylulose 5-phosphate; ribulose-phosphate 3-epimerase 1771547 rpe 1014585 rpe Streptococcus agalactiae 2603V/R ribulose-phosphate 3-epimerase NP_688766.1 1770885 R 208435 CDS NP_688767.1 22537916 1014586 complement(1771554..1772426) 1 NC_004116.1 EngC; RsgA; CpgA; circularly permuted GTPase; ribosome small subunit-dependent GTPase A; has the pattern G4-G1-G3 as opposed to other GTPases; interacts strongly with 30S ribosome which stimulates GTPase activity; ribosome-associated GTPase 1772426 1014586 SAG1777 Streptococcus agalactiae 2603V/R ribosome-associated GTPase NP_688767.1 1771554 R 208435 CDS NP_688768.1 22537917 1014587 complement(1772582..1773433) 1 NC_004116.1 similar to GB:D28496 SP:P36999 PID:460699 GB:U00096 PID:1736466; identified by sequence similarity; rRNA (guanine-N1-)-methyltransferase 1773433 1014587 SAG1778 Streptococcus agalactiae 2603V/R rRNA (guanine-N1-)-methyltransferase NP_688768.1 1772582 R 208435 CDS NP_688769.1 22537918 1014588 complement(1773437..1774309) 1 NC_004116.1 catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin; dimethyladenosine transferase 1774309 ksgA 1014588 ksgA Streptococcus agalactiae 2603V/R dimethyladenosine transferase NP_688769.1 1773437 R 208435 CDS NP_688770.1 22537919 1014589 complement(1774389..1774880) 1 NC_004116.1 hypothetical protein 1774880 1014589 SAG1780 Streptococcus agalactiae 2603V/R hypothetical protein NP_688770.1 1774389 R 208435 CDS NP_688771.1 22537920 1014590 complement(1774899..1775459) 1 NC_004116.1 identified by match to PFAM protein family HMM PF01751; primase-like protein 1775459 1014590 SAG1781 Streptococcus agalactiae 2603V/R primase-like protein NP_688771.1 1774899 R 208435 CDS NP_688772.1 22537921 1014591 complement(1775446..1776228) 1 NC_004116.1 identified by match to PFAM protein family HMM PF01026; TatD family deoxyribonuclease 1776228 1014591 SAG1782 Streptococcus agalactiae 2603V/R TatD family deoxyribonuclease NP_688772.1 1775446 R 208435 CDS NP_688773.1 22537922 1014592 complement(1776410..1776682) 1 NC_004116.1 hypothetical protein 1776682 1014592 SAG1783 Streptococcus agalactiae 2603V/R hypothetical protein NP_688773.1 1776410 R 208435 CDS NP_688774.1 22537923 1014593 complement(1776701..1777093) 1 NC_004116.1 hypothetical protein 1777093 1014593 SAG1784 Streptococcus agalactiae 2603V/R hypothetical protein NP_688774.1 1776701 R 208435 CDS NP_688775.1 22537924 1014594 complement(1777084..1778376) 1 NC_004116.1 hypothetical protein 1778376 1014594 SAG1785 Streptococcus agalactiae 2603V/R hypothetical protein NP_688775.1 1777084 R 208435 CDS NP_688776.1 22537925 1014595 complement(1778376..1778768) 1 NC_004116.1 identified by Glimmer2; The product of this gene was detected by Western blot analysis. For details on the method see Tettelin et al. 2002.; hypothetical protein 1778768 1014595 SAG1786 Streptococcus agalactiae 2603V/R hypothetical protein NP_688776.1 1778376 R 208435 CDS NP_688777.1 22537926 1014596 complement(1778943..1780205) 1 NC_004116.1 similar to OMNI:SP2173; identified by sequence similarity; dltD protein 1780205 dltD 1014596 dltD Streptococcus agalactiae 2603V/R dltD protein NP_688777.1 1778943 R 208435 CDS NP_688778.1 22537927 1014597 complement(1780198..1780437) 1 NC_004116.1 D-alanyl carrier protein subunit; involved in the incorporation of D-alanine into membrane-associated D-alanyl-lipoteichoic acid; D-alanyl carrier protein is the acceptor of activated D-alanine which it donates to a membrane acceptor(D-alanyl transferase) for incorporation into membrane lipoteichoic acid; D-alanine--poly(phosphoribitol) ligase subunit 2 1780437 dltC 1014597 dltC Streptococcus agalactiae 2603V/R D-alanine--poly(phosphoribitol) ligase subunit 2 NP_688778.1 1780198 R 208435 CDS NP_688779.1 22537928 1014598 complement(1780452..1781717) 1 NC_004116.1 similar to OMNI:SP2175; identified by sequence similarity; dltB protein 1781717 dltB 1014598 dltB Streptococcus agalactiae 2603V/R dltB protein NP_688779.1 1780452 R 208435 CDS NP_688780.1 22537929 1014599 complement(1781714..1783249) 1 NC_004116.1 transfers D-alanine to the D-alanyl carrier protein during the incorporation of D-alanine into lipoteichoic acid; D-alanine--poly(phosphoribitol) ligase subunit 1 1783249 dltA 1014599 dltA Streptococcus agalactiae 2603V/R D-alanine--poly(phosphoribitol) ligase subunit 1 NP_688780.1 1781714 R 208435 CDS NP_688781.1 22537930 1014600 complement(1783395..1784582) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00512; sensor histidine kinase 1784582 1014600 SAG1791 Streptococcus agalactiae 2603V/R sensor histidine kinase NP_688781.1 1783395 R 208435 CDS NP_688782.1 22537931 1014601 complement(1784582..1785256) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00072; DNA-binding response regulator 1785256 1014601 SAG1792 Streptococcus agalactiae 2603V/R DNA-binding response regulator NP_688782.1 1784582 R 208435 CDS NP_688783.1 22537932 1014602 complement(1785612..1785746) 1 NC_004116.1 in Escherichia coli transcription of this gene is enhanced by polyamines; 50S ribosomal protein L34 1785746 rpmH 1014602 rpmH Streptococcus agalactiae 2603V/R 50S ribosomal protein L34 NP_688783.1 1785612 R 208435 CDS NP_688784.1 22537933 1014603 complement(1785930..1787285) 1 NC_004116.1 similar to OMNI:NTL01BH3953; identified by sequence similarity; hypothetical protein 1787285 1014603 SAG1794 Streptococcus agalactiae 2603V/R hypothetical protein NP_688784.1 1785930 R 208435 CDS NP_688785.1 22537934 1014604 1787517..1788683 1 NC_004116.1 identified by match to PFAM protein family HMM PF00665; IS30 family transposase 1788683 1014604 SAG1795 Streptococcus agalactiae 2603V/R IS30 family transposase NP_688785.1 1787517 D 208435 CDS NP_688786.1 22537935 1014605 complement(1789082..1790809) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00528; amino acid ABC transporter permease 1790809 1014605 SAG1796 Streptococcus agalactiae 2603V/R amino acid ABC transporter permease NP_688786.1 1789082 R 208435 CDS NP_688787.1 22537936 1014606 complement(1790828..1792051) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00005; amino acid ABC transporter ATP-binding protein 1792051 1014606 SAG1797 Streptococcus agalactiae 2603V/R amino acid ABC transporter ATP-binding protein NP_688787.1 1790828 R 208435 CDS NP_688788.1 22537937 1014607 1792194..1792313 1 NC_004116.1 hypothetical protein 1792313 1014607 SAG1798 Streptococcus agalactiae 2603V/R hypothetical protein NP_688788.1 1792194 D 208435 CDS NP_688789.1 22537938 1014608 complement(1792428..1794806) 1 NC_004116.1 similar to SP:Q9AEM9; identified by sequence similarity; phosphoketolase 1794806 xfp 1014608 xfp Streptococcus agalactiae 2603V/R phosphoketolase NP_688789.1 1792428 R 208435 CDS NP_688790.1 22537939 1014609 complement(1794896..1795987) 1 NC_004116.1 L-ascorbate 6-phosphate lactonase 1795987 1014609 SAG1800 Streptococcus agalactiae 2603V/R L-ascorbate 6-phosphate lactonase NP_688790.1 1794896 R 208435 CDS NP_688791.1 22537940 1014610 complement(1796304..1797983) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00874; BglG family transcriptional antiterminator 1797983 1014610 SAG1801 Streptococcus agalactiae 2603V/R BglG family transcriptional antiterminator NP_688791.1 1796304 R 208435 CDS NP_688792.1 22537941 1014611 complement(1798049..1798810) 1 NC_004116.1 hypothetical protein 1798810 1014611 SAG1802 Streptococcus agalactiae 2603V/R hypothetical protein NP_688792.1 1798049 R 208435 CDS NP_688793.1 22537942 1014612 complement(1798830..1800347) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00370; carbohydrate kinase 1800347 1014612 SAG1803 Streptococcus agalactiae 2603V/R carbohydrate kinase NP_688793.1 1798830 R 208435 CDS NP_688794.1 22537943 1014613 complement(1800413..1801402) 1 NC_004116.1 hypothetical protein 1801402 1014613 SAG1804 Streptococcus agalactiae 2603V/R hypothetical protein NP_688794.1 1800413 R 208435 CDS NP_688795.1 22537944 1014614 complement(1801424..1802875) 1 NC_004116.1 PTS system transporter subunit IIC 1802875 1014614 SAG1805 Streptococcus agalactiae 2603V/R PTS system transporter subunit IIC NP_688795.1 1801424 R 208435 CDS NP_688796.1 22537945 1014615 complement(1802973..1803929) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00389; glyoxylate reductase, NADH-dependent 1803929 1014615 SAG1806 Streptococcus agalactiae 2603V/R glyoxylate reductase, NADH-dependent NP_688796.1 1802973 R 208435 CDS NP_688797.1 22537946 1014616 complement(1803948..1804967) 1 NC_004116.1 hypothetical protein 1804967 1014616 SAG1807 Streptococcus agalactiae 2603V/R hypothetical protein NP_688797.1 1803948 R 208435 CDS NP_688798.1 22537947 1014617 complement(1805202..1806185) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00356; LacI family sugar-binding transcriptional regulator 1806185 1014617 SAG1808 Streptococcus agalactiae 2603V/R LacI family sugar-binding transcriptional regulator NP_688798.1 1805202 R 208435 CDS NP_688799.1 22537948 1014618 complement(1806349..1806996) 1 NC_004116.1 similar to novel fructose-6-phosphate aldolase from Escherichia coli; enzyme from Methanocaldococcus janaschii shows transaldolase activity; translaldolase 1806996 1014618 SAG1809 Streptococcus agalactiae 2603V/R translaldolase NP_688799.1 1806349 R 208435 CDS NP_688800.1 22537949 1014619 complement(1807007..1807723) 1 NC_004116.1 catalyzes the formation of D-xylulose 5-phosphate from L-ribulose 5-phosphate in the L-arabinose and L-ascorbate degradation pathways; L-ribulose-5-phosphate 4-epimerase 1807723 araD 1014619 araD Streptococcus agalactiae 2603V/R L-ribulose-5-phosphate 4-epimerase NP_688800.1 1807007 R 208435 CDS NP_688801.1 22537950 1014620 complement(1807725..1808588) 1 NC_004116.1 L-xylulose 5-phosphate 3-epimerase activity not yet demonstrated; may be involved in the utilization of 2,3-diketo-L-gulonate; L-xylulose 5-phosphate 3-epimerase 1808588 1014620 SAG1811 Streptococcus agalactiae 2603V/R L-xylulose 5-phosphate 3-epimerase NP_688801.1 1807725 R 208435 CDS NP_688802.1 22537951 1014621 complement(1808592..1809257) 1 NC_004116.1 catalyzes the formation of L-xylulose-5-phosphate from 3-keto-L-gulonate-6-phosphate in anaerobic L-ascorbate utilization; 3-keto-L-gulonate-6-phosphate decarboxylase 1809257 ulaD 1014621 ulaD Streptococcus agalactiae 2603V/R 3-keto-L-gulonate-6-phosphate decarboxylase NP_688802.1 1808592 R 208435 CDS NP_688803.1 22537952 1014622 complement(1809370..1809855) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00359; PTS system transporter subunit IIA 1809855 1014622 SAG1813 Streptococcus agalactiae 2603V/R PTS system transporter subunit IIA NP_688803.1 1809370 R 208435 CDS NP_688804.1 22537953 1014623 complement(1809922..1810200) 1 NC_004116.1 similar to OMNI:SP2037; identified by sequence similarity; PTS system transporter subunit IIB 1810200 1014623 SAG1814 Streptococcus agalactiae 2603V/R PTS system transporter subunit IIB NP_688804.1 1809922 R 208435 CDS NP_688805.1 22537954 1014624 complement(1810228..1811667) 1 NC_004116.1 membrane component; functions with enzymes IIB (sgaB; ulaB) and IIA (sgaA; ulaC) enzyme I and HPr for anaerobic utilization and uptake of L-ascorbate; sgaTBA are regulated by yifQ as well as Crp and Fnr; PTS system ascorbate-specific transporter subunit IIC 1811667 ulaA 1014624 ulaA Streptococcus agalactiae 2603V/R PTS system ascorbate-specific transporter subunit IIC NP_688805.1 1810228 R 208435 CDS NP_688806.1 22537955 1014625 complement(1811835..1812452) 1 NC_004116.1 hypothetical protein 1812452 1014625 SAG1816 Streptococcus agalactiae 2603V/R hypothetical protein NP_688806.1 1811835 R 208435 CDS NP_688807.1 22537956 1014626 1812611..1813084 1 NC_004116.1 hypothetical protein 1813084 1014626 SAG1817 Streptococcus agalactiae 2603V/R hypothetical protein NP_688807.1 1812611 D 208435 CDS NP_688808.1 22537957 1014627 complement(1813107..1814399) 1 NC_004116.1 catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis; adenylosuccinate synthetase 1814399 purA 1014627 purA Streptococcus agalactiae 2603V/R adenylosuccinate synthetase NP_688808.1 1813107 R 208435 CDS NP_688809.1 22537958 1014628 complement(1814769..1815791) 1 NC_004116.1 identified by sequence similarity; perfringolysin O regulator protein 1815791 pfoR 1014628 pfoR Streptococcus agalactiae 2603V/R perfringolysin O regulator protein NP_688809.1 1814769 R 208435 CDS NP_688810.1 22537959 1014629 1816153..1816827 1 NC_004116.1 hypothetical protein 1816827 1014629 SAG1820 Streptococcus agalactiae 2603V/R hypothetical protein NP_688810.1 1816153 D 208435 CDS NP_688811.1 22537960 1014630 1816997..1819249 1 NC_004116.1 Synthesizes glutathione from L-glutamate and L-cysteine via gamma-L-glutamyl-L-cysteine; bifunctional glutamate--cysteine ligase/glutathione synthetase 1819249 1014630 SAG1821 Streptococcus agalactiae 2603V/R bifunctional glutamate--cysteine ligase/glutathione synthetase NP_688811.1 1816997 D 208435 CDS NP_688812.1 22537961 1014631 1819373..1820191 1 NC_004116.1 similar to OMNI:NTL01SPL0121; identified by sequence similarity; The product of this gene was detected by Western blot analysis. For details on the method see Tettelin et al. 2002.; hypothetical protein 1820191 1014631 SAG1822 Streptococcus agalactiae 2603V/R hypothetical protein NP_688812.1 1819373 D 208435 CDS NP_688813.1 22537962 1014632 1820188..1821444 1 NC_004116.1 similar to OMNI:NTL01SPL0120; identified by sequence similarity; The product of this gene was detected by Western blot analysis. For details on the method see Tettelin et al. 2002.; hypothetical protein 1821444 1014632 SAG1823 Streptococcus agalactiae 2603V/R hypothetical protein NP_688813.1 1820188 D 208435 CDS NP_688814.1 22537963 1014633 1821584..1822459 1 NC_004116.1 becomes active under oxidative stress; four conserved cysteines bind a zinc atom when they are in the reduced state and the enzyme is inactive; oxidative stress results in oxidized cysteines, release of zinc, and binding of Hsp33 to aggregation-prone proteins; forms dimers and higher order oligomers; heat shock protein 33 1822459 hslO 1014633 hslO Streptococcus agalactiae 2603V/R heat shock protein 33 NP_688814.1 1821584 D 208435 CDS NP_688815.1 22537964 1014634 1822443..1823420 1 NC_004116.1 identified by match to PFAM protein family HMM PF01207; NifR3/Smm1 family protein 1823420 1014634 SAG1825 Streptococcus agalactiae 2603V/R NifR3/Smm1 family protein NP_688815.1 1822443 D 208435 CDS NP_688816.1 22537965 1014635 1823541..1824182 1 NC_004116.1 identified by match to PFAM protein family HMM PF01712; deoxynucleoside kinase family protein 1824182 1014635 SAG1826 Streptococcus agalactiae 2603V/R deoxynucleoside kinase family protein NP_688816.1 1823541 D 208435 CDS NP_688817.1 22537966 1014636 1824196..1824687 1 NC_004116.1 identified by match to PFAM protein family HMM PF00583; phosphinothricin N-acetyltransferase 1824687 pat 1014636 pat Streptococcus agalactiae 2603V/R phosphinothricin N-acetyltransferase NP_688817.1 1824196 D 208435 CDS NP_688818.1 22537967 1014637 complement(1824907..1827354) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00004; ATP-dependent Clp protease, ATP-binding subunit 1827354 1014637 SAG1828 Streptococcus agalactiae 2603V/R ATP-dependent Clp protease, ATP-binding subunit NP_688818.1 1824907 R 208435 CDS NP_688819.1 22537968 1014638 complement(1827351..1827815) 1 NC_004116.1 similar to GB:D26185 SP:P37568 PID:467471 GB:AL009126; identified by sequence similarity; CtsR family transcriptional regulator 1827815 ctsR 1014638 ctsR Streptococcus agalactiae 2603V/R CtsR family transcriptional regulator NP_688819.1 1827351 R 208435 CDS NP_688820.1 22537969 1014639 1827988..1828449 1 NC_004116.1 hypothetical protein 1828449 1014639 SAG1830 Streptococcus agalactiae 2603V/R hypothetical protein NP_688820.1 1827988 D 208435 CDS NP_688821.1 22537970 1014640 complement(1828608..1829648) 1 NC_004116.1 EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu; elongation factor Ts 1829648 tsf 1014640 tsf Streptococcus agalactiae 2603V/R elongation factor Ts NP_688821.1 1828608 R 208435 CDS NP_688822.1 22537971 1014641 complement(1829742..1830512) 1 NC_004116.1 one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit; 30S ribosomal protein S2 1830512 rpsB 1014641 rpsB Streptococcus agalactiae 2603V/R 30S ribosomal protein S2 NP_688822.1 1829742 R 208435 CDS NP_688823.1 22537972 1014642 1830789..1831349 1 NC_004116.1 identified by match to PFAM protein family HMM PF00578; alkyl hydroperoxide reductase 1831349 ahpC 1014642 ahpC Streptococcus agalactiae 2603V/R alkyl hydroperoxide reductase NP_688823.1 1830789 D 208435 CDS NP_688824.1 22537973 1014643 1831367..1832899 1 NC_004116.1 identified by match to PFAM protein family HMM PF00070; alkyl hydroperoxide reductase 1832899 ahpF 1014643 ahpF Streptococcus agalactiae 2603V/R alkyl hydroperoxide reductase NP_688824.1 1831367 D 208435 CDS NP_688825.1 22537974 1014645 complement(1833318..1833722) 1 NC_004116.1 hypothetical protein 1833722 1014645 SAG1835 Streptococcus agalactiae 2603V/R hypothetical protein NP_688825.1 1833318 R 208435 CDS NP_688826.1 22537975 1014646 complement(1833783..1833968) 1 NC_004116.1 hypothetical protein 1833968 1014646 SAG1836 Streptococcus agalactiae 2603V/R hypothetical protein NP_688826.1 1833783 R 208435 CDS NP_688827.1 22537976 1014647 complement(1834175..1835581) 1 NC_004116.1 identified by match to PFAM protein family HMM PF01832; prophage LambdaSa2, lysin 1835581 1014647 SAG1837 Streptococcus agalactiae 2603V/R prophage LambdaSa2, lysin NP_688827.1 1834175 R 208435 CDS NP_688828.1 22537977 1014648 complement(1835585..1835914) 1 NC_004116.1 similar to GP:13655626; identified by sequence similarity; prophage LambdaSa2, holin 1835914 1014648 SAG1838 Streptococcus agalactiae 2603V/R prophage LambdaSa2, holin NP_688828.1 1835585 R 208435 CDS NP_688829.1 22537978 1014649 complement(1835917..1836327) 1 NC_004116.1 hypothetical protein 1836327 1014649 SAG1839 Streptococcus agalactiae 2603V/R hypothetical protein NP_688829.1 1835917 R 208435 CDS NP_688830.1 22537979 1014650 complement(1836362..1836700) 1 NC_004116.1 hypothetical protein 1836700 1014650 SAG1840 Streptococcus agalactiae 2603V/R hypothetical protein NP_688830.1 1836362 R 208435 CDS NP_688831.1 22537980 1014651 complement(1836703..1836933) 1 NC_004116.1 similar to PID:1514671; identified by sequence similarity; hypothetical protein 1836933 1014651 SAG1841 Streptococcus agalactiae 2603V/R hypothetical protein NP_688831.1 1836703 R 208435 CDS NP_688832.1 22537981 1014652 complement(1836950..1840624) 1 NC_004116.1 similar to GP:10732859; identified by sequence similarity; PblB is a platelet adhesin. This version contains a 200aa insert that shows similarity (32% identity, 44% similarity over 95 residues) to SP|Q9TL08 a chloroplast enzyme which converts protoporphyrin IX (a hemoglobin precursor) into cholorophyll.; prophage LambdaSa2, PblB 1840624 1014652 SAG1842 Streptococcus agalactiae 2603V/R prophage LambdaSa2, PblB NP_688832.1 1836950 R 208435 CDS NP_688833.1 22537982 1014653 complement(1840625..1841347) 1 NC_004116.1 hypothetical protein 1841347 1014653 SAG1843 Streptococcus agalactiae 2603V/R hypothetical protein NP_688833.1 1840625 R 208435 CDS NP_688834.1 22537983 1014654 complement(1841344..1844079) 1 NC_004116.1 hypothetical protein 1844079 1014654 SAG1844 Streptococcus agalactiae 2603V/R hypothetical protein NP_688834.1 1841344 R 208435 CDS NP_688835.1 22537984 1014655 complement(1844098..1844226) 1 NC_004116.1 hypothetical protein 1844226 1014655 SAG1845 Streptococcus agalactiae 2603V/R hypothetical protein NP_688835.1 1844098 R 208435 CDS NP_688836.1 22537985 1014656 complement(1844265..1844741) 1 NC_004116.1 hypothetical protein 1844741 1014656 SAG1846 Streptococcus agalactiae 2603V/R hypothetical protein NP_688836.1 1844265 R 208435 CDS NP_688837.1 22537986 1014657 complement(1844741..1845424) 1 NC_004116.1 hypothetical protein 1845424 1014657 SAG1847 Streptococcus agalactiae 2603V/R hypothetical protein NP_688837.1 1844741 R 208435 CDS NP_688838.1 22537987 1014658 complement(1845439..1845783) 1 NC_004116.1 hypothetical protein 1845783 1014658 SAG1848 Streptococcus agalactiae 2603V/R hypothetical protein NP_688838.1 1845439 R 208435 CDS NP_688839.1 22537988 1014659 complement(1845770..1846117) 1 NC_004116.1 hypothetical protein 1846117 1014659 SAG1849 Streptococcus agalactiae 2603V/R hypothetical protein NP_688839.1 1845770 R 208435 CDS NP_688840.1 22537989 1014660 complement(1846117..1846422) 1 NC_004116.1 hypothetical protein 1846422 1014660 SAG1850 Streptococcus agalactiae 2603V/R hypothetical protein NP_688840.1 1846117 R 208435 CDS NP_688841.1 22537990 1014661 complement(1846419..1846754) 1 NC_004116.1 similar to GB:AE001825; identified by sequence similarity; hypothetical protein 1846754 1014661 SAG1851 Streptococcus agalactiae 2603V/R hypothetical protein NP_688841.1 1846419 R 208435 CDS NP_688842.1 22537991 1014662 complement(1846775..1848037) 1 NC_004116.1 hypothetical protein 1848037 1014662 SAG1852 Streptococcus agalactiae 2603V/R hypothetical protein NP_688842.1 1846775 R 208435 CDS NP_688843.1 22537992 1014663 complement(1848048..1848590) 1 NC_004116.1 similar to OMNI:CC2786; identified by sequence similarity; prophage LambdaSa2, protease 1848590 1014663 SAG1853 Streptococcus agalactiae 2603V/R prophage LambdaSa2, protease NP_688843.1 1848048 R 208435 CDS NP_688844.1 22537993 1014664 complement(1848640..1849782) 1 NC_004116.1 hypothetical protein 1849782 1014664 SAG1854 Streptococcus agalactiae 2603V/R hypothetical protein NP_688844.1 1848640 R 208435 CDS NP_688845.1 22537994 1014665 complement(1849791..1851503) 1 NC_004116.1 identified by match to PFAM protein family HMM PF03354; prophage LambdaSa2, terminase large subunit 1851503 1014665 SAG1855 Streptococcus agalactiae 2603V/R prophage LambdaSa2, terminase large subunit NP_688845.1 1849791 R 208435 CDS NP_688846.1 22537995 1014666 complement(1851496..1851981) 1 NC_004116.1 hypothetical protein 1851981 1014666 SAG1856 Streptococcus agalactiae 2603V/R hypothetical protein NP_688846.1 1851496 R 208435 CDS NP_688847.1 22537996 1014667 complement(1852069..1852428) 1 NC_004116.1 identified by match to PFAM protein family HMM PF01844; prophage LambdaSa2, HNH endonuclease family protein 1852428 1014667 SAG1857 Streptococcus agalactiae 2603V/R prophage LambdaSa2, HNH endonuclease family protein NP_688847.1 1852069 R 208435 CDS NP_688848.1 22537997 1014668 complement(1852428..1852715) 1 NC_004116.1 hypothetical protein 1852715 1014668 SAG1858 Streptococcus agalactiae 2603V/R hypothetical protein NP_688848.1 1852428 R 208435 CDS NP_688849.1 22537998 1014669 complement(1853005..1853547) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00589; prophage LambdaSa2, site-specific recombinase phage integrase family protein 1853547 1014669 SAG1859 Streptococcus agalactiae 2603V/R prophage LambdaSa2, site-specific recombinase phage integrase family protein NP_688849.1 1853005 R 208435 CDS NP_688850.1 22537999 1014670 complement(1853657..1854121) 1 NC_004116.1 hypothetical protein 1854121 1014670 SAG1860 Streptococcus agalactiae 2603V/R hypothetical protein NP_688850.1 1853657 R 208435 CDS NP_688851.1 22538000 1014671 complement(1854118..1854477) 1 NC_004116.1 identified by match to PFAM protein family HMM PF01381; prophage LambdaSa2, Cro/CI family transcriptional regulator 1854477 1014671 SAG1861 Streptococcus agalactiae 2603V/R prophage LambdaSa2, Cro/CI family transcriptional regulator NP_688851.1 1854118 R 208435 CDS NP_688852.1 22538001 1014672 complement(1854462..1854722) 1 NC_004116.1 hypothetical protein 1854722 1014672 SAG1862 Streptococcus agalactiae 2603V/R hypothetical protein NP_688852.1 1854462 R 208435 CDS NP_688853.1 22538002 1014673 complement(1854732..1855148) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00436; prophage LambdaSa2, single-strand binding protein 1855148 ssb-4 1014673 ssb-4 Streptococcus agalactiae 2603V/R prophage LambdaSa2, single-strand binding protein NP_688853.1 1854732 R 208435 CDS NP_688854.1 22538003 1014674 complement(1855138..1855344) 1 NC_004116.1 hypothetical protein 1855344 1014674 SAG1864 Streptococcus agalactiae 2603V/R hypothetical protein NP_688854.1 1855138 R 208435 CDS NP_688855.1 22538004 1014675 complement(1855341..1855565) 1 NC_004116.1 hypothetical protein 1855565 1014675 SAG1865 Streptococcus agalactiae 2603V/R hypothetical protein NP_688855.1 1855341 R 208435 CDS NP_688856.1 22538005 1014676 complement(1855697..1856026) 1 NC_004116.1 hypothetical protein 1856026 1014676 SAG1866 Streptococcus agalactiae 2603V/R hypothetical protein NP_688856.1 1855697 R 208435 CDS NP_688857.1 22538006 1014677 complement(1856026..1856517) 1 NC_004116.1 hypothetical protein 1856517 1014677 SAG1867 Streptococcus agalactiae 2603V/R hypothetical protein NP_688857.1 1856026 R 208435 CDS NP_688858.1 22538007 1014678 complement(1856510..1856914) 1 NC_004116.1 hypothetical protein 1856914 1014678 SAG1868 Streptococcus agalactiae 2603V/R hypothetical protein NP_688858.1 1856510 R 208435 CDS NP_688859.1 22538008 1014679 complement(1856911..1858224) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00145; Possibly an isoschizomer of Spn5252IP.; prophage LambdaSa2, type II DNA modification methyltransferase 1858224 1014679 SAG1869 Streptococcus agalactiae 2603V/R prophage LambdaSa2, type II DNA modification methyltransferase NP_688859.1 1856911 R 208435 CDS NP_688860.1 22538009 1014680 complement(1858224..1859045) 1 NC_004116.1 prophage LambdaSa2, DNA replication protein DnaC 1859045 1014680 SAG1870 Streptococcus agalactiae 2603V/R prophage LambdaSa2, DNA replication protein DnaC NP_688860.1 1858224 R 208435 CDS NP_688861.1 22538010 1014682 complement(1859770..1860372) 1 NC_004116.1 hypothetical protein 1860372 1014682 SAG1872 Streptococcus agalactiae 2603V/R hypothetical protein NP_688861.1 1859770 R 208435 CDS NP_688862.1 22538011 1014683 complement(1860374..1861705) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00772; In low GC Gram-postive bacteria this is known as dnaC. In other prokaryotes, functional equivalent known as dnaB.; prophage LambdaSa2, replicative DNA helicase 1861705 dnaC-1 1014683 dnaC-1 Streptococcus agalactiae 2603V/R prophage LambdaSa2, replicative DNA helicase NP_688862.1 1860374 R 208435 CDS NP_688863.1 22538012 1014684 complement(1861714..1861977) 1 NC_004116.1 hypothetical protein 1861977 1014684 SAG1874 Streptococcus agalactiae 2603V/R hypothetical protein NP_688863.1 1861714 R 208435 CDS NP_688864.1 22538013 1014685 complement(1861956..1862240) 1 NC_004116.1 hypothetical protein 1862240 1014685 SAG1875 Streptococcus agalactiae 2603V/R hypothetical protein NP_688864.1 1861956 R 208435 CDS NP_688865.1 22538014 1014686 complement(1862240..1862770) 1 NC_004116.1 identified by match to PFAM protein family HMM PF01844; prophage LambdaSa2, HNH endonuclease family protein 1862770 1014686 SAG1876 Streptococcus agalactiae 2603V/R prophage LambdaSa2, HNH endonuclease family protein NP_688865.1 1862240 R 208435 CDS NP_688866.1 22538015 1014687 complement(1862833..1863543) 1 NC_004116.1 identified by match to PFAM protein family HMM PF02498; prophage LambdaSa2, antirepressor protein 1863543 1014687 SAG1877 Streptococcus agalactiae 2603V/R prophage LambdaSa2, antirepressor protein NP_688866.1 1862833 R 208435 CDS NP_688867.1 22538016 1014688 complement(1863546..1863854) 1 NC_004116.1 similar to GP:3676450; identified by sequence similarity; hypothetical protein 1863854 1014688 SAG1878 Streptococcus agalactiae 2603V/R hypothetical protein NP_688867.1 1863546 R 208435 CDS NP_688868.1 22538017 1014689 1863816..1864286 1 NC_004116.1 hypothetical protein 1864286 1014689 SAG1879 Streptococcus agalactiae 2603V/R hypothetical protein NP_688868.1 1863816 D 208435 CDS NP_688869.1 22538018 1014690 complement(1864269..1864433) 1 NC_004116.1 hypothetical protein 1864433 1014690 SAG1880 Streptococcus agalactiae 2603V/R hypothetical protein NP_688869.1 1864269 R 208435 CDS NP_688870.1 22538019 1014691 complement(1864415..1864570) 1 NC_004116.1 hypothetical protein 1864570 1014691 SAG1881 Streptococcus agalactiae 2603V/R hypothetical protein NP_688870.1 1864415 R 208435 CDS NP_688871.1 22538020 1014692 1864719..1865081 1 NC_004116.1 prophage LambdaSa2, repressor protein 1865081 1014692 SAG1882 Streptococcus agalactiae 2603V/R prophage LambdaSa2, repressor protein NP_688871.1 1864719 D 208435 CDS NP_688872.1 22538021 1014693 1865082..1865468 1 NC_004116.1 hypothetical protein 1865468 1014693 SAG1883 Streptococcus agalactiae 2603V/R hypothetical protein NP_688872.1 1865082 D 208435 CDS NP_688873.1 22538022 1014694 1865521..1865925 1 NC_004116.1 hypothetical protein 1865925 1014694 SAG1884 Streptococcus agalactiae 2603V/R hypothetical protein NP_688873.1 1865521 D 208435 CDS NP_688874.1 22538023 1014695 1866047..1867117 1 NC_004116.1 identified by match to PFAM protein family HMM PF00589; prophage LambdaSa2, site-specific recombinase phage integrase family protein 1867117 1014695 SAG1885 Streptococcus agalactiae 2603V/R prophage LambdaSa2, site-specific recombinase phage integrase family protein NP_688874.1 1866047 D 208435 CDS NP_688875.1 22538024 1014696 1867119..1867217 1 NC_004116.1 hypothetical protein 1867217 1014696 SAG1886 Streptococcus agalactiae 2603V/R hypothetical protein NP_688875.1 1867119 D 208435 CDS NP_688876.1 22538025 1014697 complement(1867260..1869329) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00999; Na+/H+ exchanger family protein 1869329 1014697 SAG1887 Streptococcus agalactiae 2603V/R Na+/H+ exchanger family protein NP_688876.1 1867260 R 208435 CDS NP_688877.1 22538026 1014698 complement(1869331..1869567) 1 NC_004116.1 hypothetical protein 1869567 1014698 SAG1888 Streptococcus agalactiae 2603V/R hypothetical protein NP_688877.1 1869331 R 208435 CDS NP_688878.1 22538027 1014699 1869734..1870687 1 NC_004116.1 identified by match to PFAM protein family HMM PF02016; microcin immunity protein MccF 1870687 1014699 SAG1889 Streptococcus agalactiae 2603V/R microcin immunity protein MccF NP_688878.1 1869734 D 208435 CDS NP_688879.1 22538028 1014700 complement(1870737..1872632) 1 NC_004116.1 identified by match to PFAM protein family HMM PF01431; endopeptidase O 1872632 pepO 1014700 pepO Streptococcus agalactiae 2603V/R endopeptidase O NP_688879.1 1870737 R 208435 CDS NP_688880.1 22538029 1014701 1872780..1873763 1 NC_004116.1 identified by match to PFAM protein family HMM PF01408; Gfo/Idh/MocA family oxidoreductase 1873763 1014701 SAG1891 Streptococcus agalactiae 2603V/R Gfo/Idh/MocA family oxidoreductase NP_688880.1 1872780 D 208435 CDS NP_688881.1 22538030 1014702 complement(1873809..1874885) 1 NC_004116.1 hypothetical protein 1874885 1014702 SAG1892 Streptococcus agalactiae 2603V/R hypothetical protein NP_688881.1 1873809 R 208435 CDS NP_688882.1 22538031 1014703 complement(1874869..1875048) 1 NC_004116.1 hypothetical protein 1875048 1014703 SAG1893 Streptococcus agalactiae 2603V/R hypothetical protein NP_688882.1 1874869 R 208435 CDS NP_688883.1 22538032 1014704 1875084..1875728 1 NC_004116.1 identified by match to PFAM protein family HMM PF00027; cyclic nucleotide-binding protein 1875728 1014704 SAG1894 Streptococcus agalactiae 2603V/R cyclic nucleotide-binding protein NP_688883.1 1875084 D 208435 CDS NP_688884.1 22538033 1014705 1875794..1876408 1 NC_004116.1 cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+); peptide deformylase 1876408 def 1014705 def Streptococcus agalactiae 2603V/R peptide deformylase NP_688884.1 1875794 D 208435 CDS NP_688885.1 22538034 1014706 complement(1876479..1877480) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00532; RegR family transcriptional regulator 1877480 regR 1014706 regR Streptococcus agalactiae 2603V/R RegR family transcriptional regulator NP_688885.1 1876479 R 208435 CDS NP_688886.1 22538035 1014707 complement(1877560..1879464) 1 NC_004116.1 hypothetical protein 1879464 1014707 SAG1897 Streptococcus agalactiae 2603V/R hypothetical protein NP_688886.1 1877560 R 208435 CDS NP_688887.1 22538036 1014708 complement(1879544..1880359) 1 NC_004116.1 PTS system transporter subunit IID 1880359 1014708 SAG1898 Streptococcus agalactiae 2603V/R PTS system transporter subunit IID NP_688887.1 1879544 R 208435 CDS NP_688888.1 22538037 1014709 complement(1880346..1881212) 1 NC_004116.1 PTS system transporter subunit IIC 1881212 1014709 SAG1899 Streptococcus agalactiae 2603V/R PTS system transporter subunit IIC NP_688888.1 1880346 R 208435 CDS NP_688889.1 22538038 1014710 complement(1881248..1881742) 1 NC_004116.1 PTS system transporter subunit IIB 1881742 1014710 SAG1900 Streptococcus agalactiae 2603V/R PTS system transporter subunit IIB NP_688889.1 1881248 R 208435 CDS NP_688890.1 22538039 1014711 complement(1881797..1882993) 1 NC_004116.1 similar to GP:5869507; identified by sequence similarity; glucuronyl hydrolase 1882993 1014711 SAG1901 Streptococcus agalactiae 2603V/R glucuronyl hydrolase NP_688890.1 1881797 R 208435 CDS NP_688891.1 22538040 1014712 complement(1882996..1883430) 1 NC_004116.1 PTS system transporter subunit IIA 1883430 1014712 SAG1902 Streptococcus agalactiae 2603V/R PTS system transporter subunit IIA NP_688891.1 1882996 R 208435 CDS NP_688892.1 22538041 1014713 1883531..1883635 1 NC_004116.1 hypothetical protein 1883635 1014713 SAG1903 Streptococcus agalactiae 2603V/R hypothetical protein NP_688892.1 1883531 D 208435 CDS NP_688893.1 22538042 1014714 1883708..1884520 1 NC_004116.1 Involved in the nonphosphorylative, ketogenic oxidation of glucose and oxidizes gluconate to 5-ketogluconate; gluconate 5-dehydrogenase 1884520 1014714 SAG1904 Streptococcus agalactiae 2603V/R gluconate 5-dehydrogenase NP_688893.1 1883708 D 208435 CDS NP_688894.1 22538043 1014715 1884537..1885175 1 NC_004116.1 hypothetical protein 1885175 1014715 SAG1905 Streptococcus agalactiae 2603V/R hypothetical protein NP_688894.1 1884537 D 208435 CDS NP_688895.1 22538044 1014716 1885201..1886208 1 NC_004116.1 identified by match to PFAM protein family HMM PF00294; carbohydrate kinase 1886208 1014716 SAG1906 Streptococcus agalactiae 2603V/R carbohydrate kinase NP_688895.1 1885201 D 208435 CDS NP_688896.1 22538045 1014717 1886220..1886858 1 NC_004116.1 catalyzes the formation of pyruvate and glyoxylate from 4-hydroxy-2-oxoglutarate; or pyruvate and D-glyceraldehyde 3-phosphate from 2-dehydro-3-deoxy-D-glyconate 6-phosphate; keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase 1886858 eda-2 1014717 eda-2 Streptococcus agalactiae 2603V/R keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase NP_688896.1 1886220 D 208435 CDS NP_688897.1 22538046 1014718 1887919..1889418 1 NC_004116.1 hypothetical protein 1889418 1014718 SAG1908 Streptococcus agalactiae 2603V/R hypothetical protein NP_688897.1 1887919 D 208435 CDS NP_688898.1 22538047 1014719 complement(1889589..1890203) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00881; nitroreductase family protein 1890203 1014719 SAG1909 Streptococcus agalactiae 2603V/R nitroreductase family protein NP_688898.1 1889589 R 208435 CDS NP_688899.1 22538048 1014720 complement(1890336..1890761) 1 NC_004116.1 identified by match to PFAM protein family HMM PF01047; MarR family transcriptional regulator 1890761 1014720 SAG1910 Streptococcus agalactiae 2603V/R MarR family transcriptional regulator NP_688899.1 1890336 R 208435 CDS NP_688900.1 22538049 1014721 complement(1890888..1895294) 1 NC_004116.1 catalyzes DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time; required for leading strand synthesis; PolC exhibits 3' to 5' exonuclease activity; DNA polymerase III PolC 1895294 polC 1014721 polC Streptococcus agalactiae 2603V/R DNA polymerase III PolC NP_688900.1 1890888 R 208435 CDS NP_688901.1 22538050 1014722 complement(1895417..1896001) 1 NC_004116.1 identified by match to PFAM protein family HMM PF01832; N-acetylmuramoyl-L-alanine amidase 1896001 1014722 SAG1912 Streptococcus agalactiae 2603V/R N-acetylmuramoyl-L-alanine amidase NP_688901.1 1895417 R 208435 CDS NP_688902.1 22538051 1014723 complement(1896126..1897979) 1 NC_004116.1 catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro); prolyl-tRNA synthetase 1897979 proS 1014723 proS Streptococcus agalactiae 2603V/R prolyl-tRNA synthetase NP_688902.1 1896126 R 208435 CDS NP_688903.1 22538052 1014724 complement(1898071..1899330) 1 NC_004116.1 identified by match to TIGR protein family HMM TIGR00054; zinc metalloprotease 1899330 1014724 SAG1914 Streptococcus agalactiae 2603V/R zinc metalloprotease NP_688903.1 1898071 R 208435 CDS NP_688904.1 22538053 1014725 complement(1899361..1900155) 1 NC_004116.1 identified by match to PFAM protein family HMM PF01148; phosphatidate cytidylyltransferase 1900155 cdsA 1014725 cdsA Streptococcus agalactiae 2603V/R phosphatidate cytidylyltransferase NP_688904.1 1899361 R 208435 CDS NP_688905.1 22538054 1014726 complement(1900170..1900922) 1 NC_004116.1 catalyzes the formation of undecaprenyl pyrophosphate from isopentenyl pyrophosphate; undecaprenyl pyrophosphate synthase 1900922 uppS 1014726 uppS Streptococcus agalactiae 2603V/R undecaprenyl pyrophosphate synthase NP_688905.1 1900170 R 208435 CDS NP_688906.1 22538055 1014727 complement(1901089..1901430) 1 NC_004116.1 member of preprotein translocase; forms a heterotrimer with SecD and SecF; links the SecD/SecF/YajC/YidC complex with the SecY/SecE/SecG complex; preprotein translocase subunit YajC 1901430 yajC 1014727 yajC Streptococcus agalactiae 2603V/R preprotein translocase subunit YajC NP_688906.1 1901089 R 208435 CDS NP_688907.1 22538056 1014728 complement(1901507..1901851) 1 NC_004116.1 The product of this gene was detected by Western blot analysis. For details on the method see Tettelin et al. 2002.; hypothetical protein 1901851 1014728 SAG1918 Streptococcus agalactiae 2603V/R hypothetical protein NP_688907.1 1901507 R 208435 CDS NP_688908.1 22538057 1014729 complement(1902042..1903205) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00390; malate oxidoreductase 1903205 1014729 SAG1919 Streptococcus agalactiae 2603V/R malate oxidoreductase NP_688908.1 1902042 R 208435 CDS NP_688909.1 22538058 1014730 complement(1903230..1904567) 1 NC_004116.1 identified by match to PFAM protein family HMM PF03390; CCS family citrate carrier protein 1904567 1014730 SAG1920 Streptococcus agalactiae 2603V/R CCS family citrate carrier protein NP_688909.1 1903230 R 208435 CDS NP_688910.1 22538059 1014731 1904721..1906247 1 NC_004116.1 similar to OMNI:NTL01SPL0863; identified by sequence similarity; sensor histidine kinase 1906247 1014731 SAG1921 Streptococcus agalactiae 2603V/R sensor histidine kinase NP_688910.1 1904721 D 208435 CDS NP_688911.1 22538060 1014732 1906249..1906938 1 NC_004116.1 identified by match to PFAM protein family HMM PF00072; response regulator 1906938 1014732 SAG1922 Streptococcus agalactiae 2603V/R response regulator NP_688911.1 1906249 D 208435 CDS NP_688912.1 22538061 1014733 complement(1906951..1907946) 1 NC_004116.1 identified by match to PFAM protein family HMM PF01370; UDP-glucose 4-epimerase 1907946 galE 1014733 galE Streptococcus agalactiae 2603V/R UDP-glucose 4-epimerase NP_688912.1 1906951 R 208435 CDS NP_688913.1 22538062 1014734 complement(1908034..1909641) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00128; glucan 1,6-alpha-glucosidase 1909641 dexB 1014734 dexB Streptococcus agalactiae 2603V/R glucan 1,6-alpha-glucosidase NP_688913.1 1908034 R 208435 CDS NP_688914.1 22538063 1014735 complement(1909769..1910902) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00005; sugar ABC transporter ATP-binding protein 1910902 1014735 SAG1925 Streptococcus agalactiae 2603V/R sugar ABC transporter ATP-binding protein NP_688914.1 1909769 R 208435 CDS NP_688915.1 22538064 1014736 complement(1911003..1911854) 1 NC_004116.1 identified by match to TIGR protein family HMM TIGR01199; helix-turn-helix domain-containing protein 1911854 1014736 SAG1926 Streptococcus agalactiae 2603V/R helix-turn-helix domain-containing protein NP_688915.1 1911003 R 208435 CDS NP_688916.1 22538065 1014737 complement(1911949..1912845) 1 NC_004116.1 identified by match to PFAM protein family HMM PF02693; aldolase 1 epimerase LacX 1912845 1014737 SAG1927 Streptococcus agalactiae 2603V/R aldolase 1 epimerase LacX NP_688916.1 1911949 R 208435 CDS NP_688917.1 22538066 1014738 complement(1912899..1913876) 1 NC_004116.1 catalyzes the reversible reaction of dihydroxyacetone phosphate with glyceraldehyde 3-phosphate to produce tagatose 1,6-bisphosphate; in Streptococcus pyogenes there are two paralogs of tagatose-bisphosphate aldolase, encoded by lacD1 and lacD2; expression of lacD1 is highly regulated by environmental conditions while lacD2 specializes in an efficient utilization of carbohydrate sources; tagatose 1,6-diphosphate aldolase 1913876 lacD 1014738 lacD Streptococcus agalactiae 2603V/R tagatose 1,6-diphosphate aldolase NP_688917.1 1912899 R 208435 CDS NP_688918.1 22538067 1014739 complement(1913878..1914810) 1 NC_004116.1 catalyzes the formation of tagatose 1,6-bisphosphate from tagatose 6-phosphate and ATP; tagatose-6-phosphate kinase 1914810 lacC 1014739 lacC Streptococcus agalactiae 2603V/R tagatose-6-phosphate kinase NP_688918.1 1913878 R 208435 CDS NP_688919.1 22538068 1014740 complement(1914821..1915336) 1 NC_004116.1 catalyzes the interconversion of galactose 6-phosphate to tagatose 6-phosphate; galactose-6-phosphate isomerase subunit LacB 1915336 lacB 1014740 lacB Streptococcus agalactiae 2603V/R galactose-6-phosphate isomerase subunit LacB NP_688919.1 1914821 R 208435 CDS NP_688920.1 22538069 1014741 complement(1915357..1915782) 1 NC_004116.1 catalyzes the interconversion of galactose 6-phosphate to tagatose 6-phosphate; tagatose pathway for galactose utilization; galactose-6-phosphate isomerase subunit LacA 1915782 lacA 1014741 lacA Streptococcus agalactiae 2603V/R galactose-6-phosphate isomerase subunit LacA NP_688920.1 1915357 R 208435 CDS NP_688921.1 22538070 1014742 complement(1916030..1918480) 1 NC_004116.1 identified by match to PFAM protein family HMM PF02012; neuraminidase-like protein 1918480 1014742 SAG1932 Streptococcus agalactiae 2603V/R neuraminidase-like protein NP_688921.1 1916030 R 208435 CDS NP_688922.1 22538071 1014743 complement(1918719..1920167) 1 NC_004116.1 PTS system transporter subunit IIC 1920167 1014743 SAG1933 Streptococcus agalactiae 2603V/R PTS system transporter subunit IIC NP_688922.1 1918719 R 208435 CDS NP_688923.1 22538072 1014744 complement(1920207..1920512) 1 NC_004116.1 similar to OMNI:NTL01SPL1345; identified by sequence similarity; PTS system transporter subunit IIB 1920512 1014744 SAG1934 Streptococcus agalactiae 2603V/R PTS system transporter subunit IIB NP_688923.1 1920207 R 208435 CDS NP_688924.1 22538073 1014745 complement(1920514..1920987) 1 NC_004116.1 PTS system transporter subunit IIA 1920987 1014745 SAG1935 Streptococcus agalactiae 2603V/R PTS system transporter subunit IIA NP_688924.1 1920514 R 208435 CDS NP_688925.1 22538074 1014746 1921197..1921973 1 NC_004116.1 identified by match to PFAM protein family HMM PF00455; lactose phosphotransferase system repressor 1921973 lacR-2 1014746 lacR-2 Streptococcus agalactiae 2603V/R lactose phosphotransferase system repressor NP_688925.1 1921197 D 208435 CDS NP_688926.1 22538075 1014748 complement(1924811..1925734) 1 NC_004116.1 identified by match to PFAM protein family HMM PF01297; The product of this gene was detected by Western blot analysis. For details on the method see Tettelin et al. 2002.; adhesion lipoprotein 1925734 1014748 SAG1938 Streptococcus agalactiae 2603V/R adhesion lipoprotein NP_688926.1 1924811 R 208435 CDS NP_688927.1 22538076 1014749 complement(1925989..1926432) 1 NC_004116.1 hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr); possible defense mechanism against a harmful effect of D-tyrosine; D-tyrosyl-tRNA(Tyr) deacylase 1926432 1014749 SAG1939 Streptococcus agalactiae 2603V/R D-tyrosyl-tRNA(Tyr) deacylase NP_688927.1 1925989 R 208435 CDS NP_688928.1 22538077 1014750 complement(1926442..1928658) 1 NC_004116.1 identified by match to PFAM protein family HMM PF01842; GTP pyrophosphokinase 1928658 1014750 SAG1940 Streptococcus agalactiae 2603V/R GTP pyrophosphokinase NP_688928.1 1926442 R 208435 CDS NP_688929.1 22538078 1014751 1928918..1931320 1 NC_004116.1 in Escherichia coli this is a periplasmic enzyme while in gram positive organisms it may be anchored at the cell surface; functions during ribonucleic acid degradation; 2',3'-cyclic nucleotides are first converted to 3'-nucleotide and then cleaved to yield a ribonucleotide and a phosphate; bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase/3'-nucleotidase precursor protein 1931320 cpdB 1014751 cpdB Streptococcus agalactiae 2603V/R bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase/3'-nucleotidase precursor protein NP_688929.1 1928918 D 208435 CDS NP_688930.1 22538079 1014752 1931477..1931932 1 NC_004116.1 has a stimulatory effect on the ribonucleotide reductase activity of NrdH with NrdEF; flavoprotein NrdI 1931932 nrdI-2 1014752 nrdI-2 Streptococcus agalactiae 2603V/R flavoprotein NrdI NP_688930.1 1931477 D 208435 CDS NP_688931.1 22538080 1014753 1931943..1932980 1 NC_004116.1 hypothetical protein 1932980 1014753 SAG1943 Streptococcus agalactiae 2603V/R hypothetical protein NP_688931.1 1931943 D 208435 CDS NP_688932.1 22538081 1014754 1932980..1933477 1 NC_004116.1 hypothetical protein 1933477 1014754 SAG1944 Streptococcus agalactiae 2603V/R hypothetical protein NP_688932.1 1932980 D 208435 CDS NP_688933.1 22538082 1014755 complement(1933699..1934736) 1 NC_004116.1 identified by match to PFAM protein family HMM PF01547; iron ABC transporter substrate-binding protein 1934736 1014755 SAG1945 Streptococcus agalactiae 2603V/R iron ABC transporter substrate-binding protein NP_688933.1 1933699 R 208435 CDS NP_688934.1 22538083 1014756 complement(1934748..1935521) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00072; DNA-binding response regulator 1935521 1014756 SAG1946 Streptococcus agalactiae 2603V/R DNA-binding response regulator NP_688934.1 1934748 R 208435 CDS NP_688935.1 22538084 1014757 complement(1935525..1937174) 1 NC_004116.1 hypothetical protein 1937174 1014757 SAG1947 Streptococcus agalactiae 2603V/R hypothetical protein NP_688935.1 1935525 R 208435 CDS NP_688936.1 22538085 1014758 complement(1937312..1938139) 1 NC_004116.1 PTS system transporter subunit IID 1938139 1014758 SAG1948 Streptococcus agalactiae 2603V/R PTS system transporter subunit IID NP_688936.1 1937312 R 208435 CDS NP_688937.1 22538086 1014759 complement(1938136..1938945) 1 NC_004116.1 PTS system transporter subunit IIC 1938945 1014759 SAG1949 Streptococcus agalactiae 2603V/R PTS system transporter subunit IIC NP_688937.1 1938136 R 208435 CDS NP_688938.1 22538087 1014760 complement(1938961..1939452) 1 NC_004116.1 PTS system transporter subunit IIB 1939452 1014760 SAG1950 Streptococcus agalactiae 2603V/R PTS system transporter subunit IIB NP_688938.1 1938961 R 208435 CDS NP_688939.1 22538088 1014761 complement(1939470..1939895) 1 NC_004116.1 PTS system transporter subunit IIA 1939895 1014761 SAG1951 Streptococcus agalactiae 2603V/R PTS system transporter subunit IIA NP_688939.1 1939470 R 208435 CDS NP_688940.1 22538089 1014762 complement(1940142..1941203) 1 NC_004116.1 similar to GP:7960293; identified by sequence similarity; hypothetical protein 1941203 1014762 SAG1952 Streptococcus agalactiae 2603V/R hypothetical protein NP_688940.1 1940142 R 208435 CDS NP_688941.1 22538090 1014763 1941228..1941410 1 NC_004116.1 hypothetical protein 1941410 1014763 SAG1953 Streptococcus agalactiae 2603V/R hypothetical protein NP_688941.1 1941228 D 208435 CDS NP_688942.1 22538091 1014764 complement(1941405..1942559) 1 NC_004116.1 hypothetical protein 1942559 1014764 SAG1954 Streptococcus agalactiae 2603V/R hypothetical protein NP_688942.1 1941405 R 208435 CDS NP_688943.1 22538092 1014765 complement(1942565..1943413) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00005; ABC transporter ATP-binding protein 1943413 1014765 SAG1955 Streptococcus agalactiae 2603V/R ABC transporter ATP-binding protein NP_688943.1 1942565 R 208435 CDS NP_688944.1 22538093 1014767 complement(1943904..1944656) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00072; response regulator 1944656 1014767 SAG1957 Streptococcus agalactiae 2603V/R response regulator NP_688944.1 1943904 R 208435 CDS NP_688945.1 22538094 1014768 complement(1944933..1945763) 1 NC_004116.1 hypothetical protein 1945763 1014768 SAG1958 Streptococcus agalactiae 2603V/R hypothetical protein NP_688945.1 1944933 R 208435 CDS NP_688946.1 22538095 1014769 complement(1945802..1947985) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00358; PTS system transporter subunit IIABC 1947985 1014769 SAG1959 Streptococcus agalactiae 2603V/R PTS system transporter subunit IIABC NP_688946.1 1945802 R 208435 CDS NP_688947.1 22538096 1014770 complement(1948143..1949798) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00512; sensor histidine kinase 1949798 1014770 SAG1960 Streptococcus agalactiae 2603V/R sensor histidine kinase NP_688947.1 1948143 R 208435 CDS NP_688948.1 22538097 1014771 complement(1949791..1950468) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00072; phosphate regulon response regulator PhoB 1950468 phoB 1014771 phoB Streptococcus agalactiae 2603V/R phosphate regulon response regulator PhoB NP_688948.1 1949791 R 208435 CDS NP_688949.1 22538098 1014772 complement(1950468..1951124) 1 NC_004116.1 identified by match to PFAM protein family HMM PF01895; phosphate transport system regulatory protein PhoU 1951124 1014772 SAG1962 Streptococcus agalactiae 2603V/R phosphate transport system regulatory protein PhoU NP_688949.1 1950468 R 208435 CDS NP_688950.1 22538099 1014773 complement(1951121..1951882) 1 NC_004116.1 ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation; phosphate transporter ATP-binding protein 1951882 1014773 SAG1963 Streptococcus agalactiae 2603V/R phosphate transporter ATP-binding protein NP_688950.1 1951121 R 208435 CDS NP_688951.1 22538100 1014774 complement(1951863..1952741) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00528; phosphate ABC transporter permease 1952741 1014774 SAG1964 Streptococcus agalactiae 2603V/R phosphate ABC transporter permease NP_688951.1 1951863 R 208435 CDS NP_688952.1 22538101 1014775 complement(1952743..1953588) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00528; phosphate ABC transporter permease 1953588 1014775 SAG1965 Streptococcus agalactiae 2603V/R phosphate ABC transporter permease NP_688952.1 1952743 R 208435 CDS NP_688953.1 22538102 1014776 complement(1953603..1954484) 1 NC_004116.1 hemolysin 1954484 1014776 SAG1966 Streptococcus agalactiae 2603V/R hemolysin NP_688953.1 1953603 R 208435 CDS NP_688954.1 22538103 1014777 complement(1954685..1955272) 1 NC_004116.1 hypothetical protein 1955272 1014777 SAG1967 Streptococcus agalactiae 2603V/R hypothetical protein NP_688954.1 1954685 R 208435 CDS NP_688955.1 22538104 1014778 complement(1955269..1956009) 1 NC_004116.1 in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA; cells lacking this function can grow, but are outcompeted by wild-type; SAM-dependent m(3)U1498 methyltransferase; 16S ribosomal RNA methyltransferase RsmE 1956009 1014778 SAG1968 Streptococcus agalactiae 2603V/R 16S ribosomal RNA methyltransferase RsmE NP_688955.1 1955269 R 208435 CDS NP_688956.1 22538105 1014779 complement(1956009..1956962) 1 NC_004116.1 methylates ribosomal protein L11 at multiple amino acid positions; mutations of these genes in Escherichia coli or Thermus thermophilus has no apparent phenotype; 50S ribosomal protein L11 methyltransferase 1956962 prmA 1014779 prmA Streptococcus agalactiae 2603V/R 50S ribosomal protein L11 methyltransferase NP_688956.1 1956009 R 208435 CDS NP_688957.1 22538106 1014780 complement(1956959..1957267) 1 NC_004116.1 hypothetical protein 1957267 1014780 SAG1970 Streptococcus agalactiae 2603V/R hypothetical protein NP_688957.1 1956959 R 208435 CDS NP_688958.1 22538107 1014781 1957329..1957454 1 NC_004116.1 hypothetical protein 1957454 1014781 SAG1971 Streptococcus agalactiae 2603V/R hypothetical protein NP_688958.1 1957329 D 208435 CDS NP_688959.1 22538108 1014782 1957541..1958257 1 NC_004116.1 identified by match to PFAM protein family HMM PF00376; MerR family transcriptional regulator 1958257 1014782 SAG1972 Streptococcus agalactiae 2603V/R MerR family transcriptional regulator NP_688959.1 1957541 D 208435 CDS NP_688960.1 22538109 1014783 complement(1958296..1958766) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00583; acetyltransferase 1958766 1014783 SAG1973 Streptococcus agalactiae 2603V/R acetyltransferase NP_688960.1 1958296 R 208435 CDS NP_688961.1 22538110 1014784 complement(1958738..1959196) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00293; MutT/nudix family protein 1959196 1014784 SAG1974 Streptococcus agalactiae 2603V/R MutT/nudix family protein NP_688961.1 1958738 R 208435 CDS NP_688962.1 22538111 1014785 complement(1959183..1959326) 1 NC_004116.1 hypothetical protein 1959326 1014785 SAG1975 Streptococcus agalactiae 2603V/R hypothetical protein NP_688962.1 1959183 R 208435 CDS NP_688963.1 22538112 1014786 complement(1959332..1959802) 1 NC_004116.1 hypothetical protein 1959802 1014786 SAG1976 Streptococcus agalactiae 2603V/R hypothetical protein NP_688963.1 1959332 R 208435 CDS NP_688964.1 22538113 1014787 1960129..1960620 1 NC_004116.1 identified by match to PFAM protein family HMM PF00583; acetyltransferase 1960620 1014787 SAG1977 Streptococcus agalactiae 2603V/R acetyltransferase NP_688964.1 1960129 D 208435 CDS NP_688965.1 22538114 1014788 1960613..1961881 1 NC_004116.1 identified by match to PFAM protein family HMM PF00004; recombination factor protein RarA 1961881 1014788 SAG1978 Streptococcus agalactiae 2603V/R recombination factor protein RarA NP_688965.1 1960613 D 208435 CDS NP_688966.1 22538115 1014790 complement(1962397..1963158) 1 NC_004116.1 hypothetical protein 1963158 1014790 SAG1979 Streptococcus agalactiae 2603V/R hypothetical protein NP_688966.1 1962397 R 208435 CDS NP_688967.1 22538116 1014791 complement(1963155..1964057) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00005; ABC transporter ATP-binding protein 1964057 1014791 SAG1980 Streptococcus agalactiae 2603V/R ABC transporter ATP-binding protein NP_688967.1 1963155 R 208435 CDS NP_688968.1 22538117 1014792 complement(1964054..1964260) 1 NC_004116.1 hypothetical protein 1964260 1014792 SAG1981 Streptococcus agalactiae 2603V/R hypothetical protein NP_688968.1 1964054 R 208435 CDS NP_688969.1 22538118 1014793 complement(1964250..1965329) 1 NC_004116.1 identified by match to PFAM protein family HMM PF01381; Cro/CI family transcriptional regulator 1965329 1014793 SAG1982 Streptococcus agalactiae 2603V/R Cro/CI family transcriptional regulator NP_688969.1 1964250 R 208435 CDS NP_688970.1 22538119 1014794 1965710..1966027 1 NC_004116.1 hypothetical protein 1966027 1014794 SAG1983 Streptococcus agalactiae 2603V/R hypothetical protein NP_688970.1 1965710 D 208435 CDS NP_688971.1 22538120 1014795 1966024..1966590 1 NC_004116.1 hypothetical protein 1966590 1014795 SAG1984 Streptococcus agalactiae 2603V/R hypothetical protein NP_688971.1 1966024 D 208435 CDS NP_688972.1 22538121 1014796 complement(1966644..1966799) 1 NC_004116.1 hypothetical protein 1966799 1014796 SAG1985 Streptococcus agalactiae 2603V/R hypothetical protein NP_688972.1 1966644 R 208435 CDS NP_688973.1 22538122 1014797 complement(1966825..1967952) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00589; phage integrase family site specific recombinase 1967952 1014797 SAG1986 Streptococcus agalactiae 2603V/R phage integrase family site specific recombinase NP_688973.1 1966825 R 208435 CDS NP_688974.1 22538123 1014798 complement(1967956..1968141) 1 NC_004116.1 hypothetical protein 1968141 1014798 SAG1987 Streptococcus agalactiae 2603V/R hypothetical protein NP_688974.1 1967956 R 208435 CDS NP_688975.1 22538124 1014799 complement(1968202..1969230) 1 NC_004116.1 hypothetical protein 1969230 1014799 SAG1988 Streptococcus agalactiae 2603V/R hypothetical protein NP_688975.1 1968202 R 208435 CDS NP_688976.1 22538125 1014800 complement(1969233..1969652) 1 NC_004116.1 hypothetical protein 1969652 1014800 SAG1989 Streptococcus agalactiae 2603V/R hypothetical protein NP_688976.1 1969233 R 208435 CDS NP_688977.1 22538126 1014801 complement(1969978..1970361) 1 NC_004116.1 hypothetical protein 1970361 1014801 SAG1990 Streptococcus agalactiae 2603V/R hypothetical protein NP_688977.1 1969978 R 208435 CDS NP_688978.1 22538127 1014802 1970585..1971199 1 NC_004116.1 identified by match to PFAM protein family HMM PF01381; Cro/CI family transcriptional regulator 1971199 1014802 SAG1991 Streptococcus agalactiae 2603V/R Cro/CI family transcriptional regulator NP_688978.1 1970585 D 208435 CDS NP_688979.1 22538128 1014803 complement(1971372..1972928) 1 NC_004116.1 similar to PID:928833; identified by sequence similarity; The product of this gene was detected by Western blot analysis. For details on the method see Tettelin et al. 2002.; hypothetical protein 1972928 1014803 SAG1992 Streptococcus agalactiae 2603V/R hypothetical protein NP_688979.1 1971372 R 208435 CDS NP_688980.1 22538129 1014804 complement(1973269..1974390) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00589; phage integrase family site specific recombinase 1974390 1014804 SAG1993 Streptococcus agalactiae 2603V/R phage integrase family site specific recombinase NP_688980.1 1973269 R 208435 CDS NP_688981.1 22538130 1014805 complement(1974440..1974766) 1 NC_004116.1 hypothetical protein 1974766 1014805 SAG1994 Streptococcus agalactiae 2603V/R hypothetical protein NP_688981.1 1974440 R 208435 CDS NP_688982.1 22538131 1014806 complement(1974959..1975591) 1 NC_004116.1 hypothetical protein 1975591 1014806 SAG1995 Streptococcus agalactiae 2603V/R hypothetical protein NP_688982.1 1974959 R 208435 CDS NP_688983.1 22538132 1014807 complement(1975672..1976463) 1 NC_004116.1 cell wall surface anchor family protein 1976463 1014807 SAG1996 Streptococcus agalactiae 2603V/R cell wall surface anchor family protein NP_688983.1 1975672 R 208435 CDS NP_688984.1 22538133 1014808 complement(1976480..1977028) 1 NC_004116.1 hypothetical protein 1977028 1014808 SAG1997 Streptococcus agalactiae 2603V/R hypothetical protein NP_688984.1 1976480 R 208435 CDS NP_688985.1 22538134 1014809 complement(1977028..1978401) 1 NC_004116.1 hypothetical protein 1978401 1014809 SAG1998 Streptococcus agalactiae 2603V/R hypothetical protein NP_688985.1 1977028 R 208435 CDS NP_688986.1 22538135 1014810 1978564..1978707 1 NC_004116.1 hypothetical protein 1978707 1014810 SAG1999 Streptococcus agalactiae 2603V/R hypothetical protein NP_688986.1 1978564 D 208435 CDS NP_688987.1 22538136 1014811 complement(1978897..1980897) 1 NC_004116.1 similar to GP:6782407; identified by sequence similarity; hypothetical protein 1980897 1014811 SAG2000 Streptococcus agalactiae 2603V/R hypothetical protein NP_688987.1 1978897 R 208435 CDS NP_688988.1 22538137 1014812 complement(1980913..1983183) 1 NC_004116.1 This gene is interrupted by an IS1381 element.; conjugal transfer protein, interruption-C 1983183 1014812 SAG2001 Streptococcus agalactiae 2603V/R conjugal transfer protein, interruption-C NP_688988.1 1980913 R 208435 CDS NP_688989.1 22538138 1014813 complement(1983230..1983619) 1 NC_004116.1 identified by match to PFAM protein family HMM PF01609; IS1381 transposase protein B 1983619 1014813 SAG2002 Streptococcus agalactiae 2603V/R IS1381 transposase protein B NP_688989.1 1983230 R 208435 CDS NP_688990.2 545902389 1014814 complement(1983652..1984275) 1 NC_004116.1 similar to OMNI:SP0537; identified by sequence similarity; IS1381 transposase protein A 1984275 1014814 SAG2003 Streptococcus agalactiae 2603V/R IS1381 transposase protein A NP_688990.2 1983652 R 208435 CDS NP_688991.1 22538140 1014816 complement(1984296..1984706) 1 NC_004116.1 hypothetical protein 1984706 1014816 SAG2005 Streptococcus agalactiae 2603V/R hypothetical protein NP_688991.1 1984296 R 208435 CDS NP_688992.1 22538141 1014817 complement(1984717..1984983) 1 NC_004116.1 hypothetical protein 1984983 1014817 SAG2006 Streptococcus agalactiae 2603V/R hypothetical protein NP_688992.1 1984717 R 208435 CDS NP_688993.1 22538142 1014818 complement(1985004..1985957) 1 NC_004116.1 hypothetical protein 1985957 1014818 SAG2007 Streptococcus agalactiae 2603V/R hypothetical protein NP_688993.1 1985004 R 208435 CDS NP_688994.1 22538143 1014819 complement(1986010..1986264) 1 NC_004116.1 hypothetical protein 1986264 1014819 SAG2008 Streptococcus agalactiae 2603V/R hypothetical protein NP_688994.1 1986010 R 208435 CDS NP_688995.1 22538144 1014820 complement(1986257..1986523) 1 NC_004116.1 hypothetical protein 1986523 1014820 SAG2009 Streptococcus agalactiae 2603V/R hypothetical protein NP_688995.1 1986257 R 208435 CDS NP_688996.1 22538145 1014821 complement(1986668..1987141) 1 NC_004116.1 hypothetical protein 1987141 1014821 SAG2010 Streptococcus agalactiae 2603V/R hypothetical protein NP_688996.1 1986668 R 208435 CDS NP_688997.1 22538146 1014822 complement(1987149..1987631) 1 NC_004116.1 hypothetical protein 1987631 1014822 SAG2011 Streptococcus agalactiae 2603V/R hypothetical protein NP_688997.1 1987149 R 208435 CDS NP_688998.1 22538147 1014823 complement(1987684..1987956) 1 NC_004116.1 hypothetical protein 1987956 1014823 SAG2012 Streptococcus agalactiae 2603V/R hypothetical protein NP_688998.1 1987684 R 208435 CDS NP_688999.1 22538148 1014824 complement(1988091..1988660) 1 NC_004116.1 hypothetical protein 1988660 1014824 SAG2013 Streptococcus agalactiae 2603V/R hypothetical protein NP_688999.1 1988091 R 208435 CDS NP_689000.1 22538149 1014825 complement(1988663..1990012) 1 NC_004116.1 hypothetical protein 1990012 1014825 SAG2014 Streptococcus agalactiae 2603V/R hypothetical protein NP_689000.1 1988663 R 208435 CDS NP_689001.1 22538150 1014826 complement(1990209..1990508) 1 NC_004116.1 identified by match to PFAM protein family HMM PF01381; Cro/CI family transcriptional regulator 1990508 1014826 SAG2015 Streptococcus agalactiae 2603V/R Cro/CI family transcriptional regulator NP_689001.1 1990209 R 208435 CDS NP_689002.1 22538151 1014827 complement(1990492..1990869) 1 NC_004116.1 hypothetical protein 1990869 1014827 SAG2016 Streptococcus agalactiae 2603V/R hypothetical protein NP_689002.1 1990492 R 208435 CDS NP_689003.1 22538152 1014828 complement(1990885..1992174) 1 NC_004116.1 identified by match to PFAM protein family HMM PF01381; Cro/CI family transcriptional regulator 1992174 1014828 SAG2017 Streptococcus agalactiae 2603V/R Cro/CI family transcriptional regulator NP_689003.1 1990885 R 208435 CDS NP_689004.1 22538153 1014829 complement(1992405..1994066) 1 NC_004116.1 identified by match to PFAM protein family HMM PF01580; DNA translocase FtsK 1994066 1014829 SAG2018 Streptococcus agalactiae 2603V/R DNA translocase FtsK NP_689004.1 1992405 R 208435 CDS NP_689005.1 22538154 1014830 complement(1994143..1994604) 1 NC_004116.1 hypothetical protein 1994604 1014830 SAG2019 Streptococcus agalactiae 2603V/R hypothetical protein NP_689005.1 1994143 R 208435 CDS NP_689006.1 22538155 1014831 complement(1994626..1994922) 1 NC_004116.1 hypothetical protein 1994922 1014831 SAG2020 Streptococcus agalactiae 2603V/R hypothetical protein NP_689006.1 1994626 R 208435 CDS NP_689007.1 22538156 1014832 complement(1994982..1997462) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00746; cell wall surface anchor family protein 1997462 1014832 SAG2021 Streptococcus agalactiae 2603V/R cell wall surface anchor family protein NP_689007.1 1994982 R 208435 CDS NP_689008.1 22538157 1014833 complement(1997467..1998720) 1 NC_004116.1 identified by match to PFAM protein family HMM PF01610; This gene is located in a transposable element that also encodes two genes for a mercuric resistance operon, and there are two copies of the transposable element in this strain.; ISL3 family transposase 1998720 1014833 SAG2022 Streptococcus agalactiae 2603V/R ISL3 family transposase NP_689008.1 1997467 R 208435 CDS NP_689009.1 22538158 1014834 complement(1998880..2000520) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00070; mercuric reductase 2000520 merA-2 1014834 merA-2 Streptococcus agalactiae 2603V/R mercuric reductase NP_689009.1 1998880 R 208435 CDS NP_689010.1 22538159 1014835 complement(2000549..2000941) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00376; mercuric resistance operon regulatory protein MerR 2000941 merR-2 1014835 merR-2 Streptococcus agalactiae 2603V/R mercuric resistance operon regulatory protein MerR NP_689010.1 2000549 R 208435 CDS NP_689011.1 22538160 1014836 2001647..2003215 1 NC_004116.1 identified by match to PFAM protein family HMM PF01566; Mn2+/Fe2+ transporter 2003215 1014836 SAG2025 Streptococcus agalactiae 2603V/R Mn2+/Fe2+ transporter NP_689011.1 2001647 D 208435 CDS NP_689012.1 22538161 1014837 complement(2003783..2004505) 1 NC_004116.1 similar to OMNI:NTL01SA2412; identified by sequence similarity; hypothetical protein 2004505 1014837 SAG2026 Streptococcus agalactiae 2603V/R hypothetical protein NP_689012.1 2003783 R 208435 CDS NP_689013.1 22538162 1014838 complement(2004509..2005126) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00005; ABC transporter ATP-binding protein 2005126 1014838 SAG2027 Streptococcus agalactiae 2603V/R ABC transporter ATP-binding protein NP_689013.1 2004509 R 208435 CDS NP_689014.1 22538163 1014839 complement(2005184..2005294) 1 NC_004116.1 hypothetical protein 2005294 1014839 SAG2028 Streptococcus agalactiae 2603V/R hypothetical protein NP_689014.1 2005184 R 208435 CDS NP_689015.1 22538164 1014840 complement(2005813..2006667) 1 NC_004116.1 similar to SP:P12055 GB:X06627 PID:46644; identified by sequence similarity; streptomycin resistance protein 2006667 1014840 SAG2029 Streptococcus agalactiae 2603V/R streptomycin resistance protein NP_689015.1 2005813 R 208435 CDS NP_689016.1 22538165 1014841 complement(2006846..2007238) 1 NC_004116.1 hypothetical protein 2007238 1014841 SAG2030 Streptococcus agalactiae 2603V/R hypothetical protein NP_689016.1 2006846 R 208435 CDS NP_689017.1 22538166 1014842 complement(2007673..2008281) 1 NC_004116.1 hypothetical protein 2008281 1014842 SAG2031 Streptococcus agalactiae 2603V/R hypothetical protein NP_689017.1 2007673 R 208435 CDS NP_689018.1 22538167 1014843 complement(2008268..2008603) 1 NC_004116.1 hypothetical protein 2008603 1014843 SAG2032 Streptococcus agalactiae 2603V/R hypothetical protein NP_689018.1 2008268 R 208435 CDS NP_689019.1 22538168 1014844 complement(2009125..2009613) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00583; acetyltransferase 2009613 1014844 SAG2033 Streptococcus agalactiae 2603V/R acetyltransferase NP_689019.1 2009125 R 208435 CDS NP_689020.1 22538169 1014845 complement(2009782..2010525) 1 NC_004116.1 similar to OMNI:NTL01BH0292; identified by sequence similarity; hypothetical protein 2010525 1014845 SAG2034 Streptococcus agalactiae 2603V/R hypothetical protein NP_689020.1 2009782 R 208435 CDS NP_689021.1 22538170 1014846 complement(2010540..2011442) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00005; ABC transporter ATP-binding protein 2011442 1014846 SAG2035 Streptococcus agalactiae 2603V/R ABC transporter ATP-binding protein NP_689021.1 2010540 R 208435 CDS NP_689022.1 22538171 1014847 complement(2011439..2011645) 1 NC_004116.1 hypothetical protein 2011645 1014847 SAG2036 Streptococcus agalactiae 2603V/R hypothetical protein NP_689022.1 2011439 R 208435 CDS NP_689023.1 22538172 1014848 complement(2011647..2012723) 1 NC_004116.1 identified by match to PFAM protein family HMM PF01381; Cro/CI family transcriptional regulator 2012723 1014848 SAG2037 Streptococcus agalactiae 2603V/R Cro/CI family transcriptional regulator NP_689023.1 2011647 R 208435 CDS NP_689024.1 22538173 1014849 complement(2012972..2013586) 1 NC_004116.1 identified by match to PFAM protein family HMM PF01569; PAP2 family protein 2013586 1014849 SAG2038 Streptococcus agalactiae 2603V/R PAP2 family protein NP_689024.1 2012972 R 208435 CDS NP_689025.1 22538174 1014850 2013800..2014096 1 NC_004116.1 hypothetical protein 2014096 1014850 SAG2039 Streptococcus agalactiae 2603V/R hypothetical protein NP_689025.1 2013800 D 208435 CDS NP_689026.1 22538175 1014851 2014113..2014673 1 NC_004116.1 hypothetical protein 2014673 1014851 SAG2040 Streptococcus agalactiae 2603V/R hypothetical protein NP_689026.1 2014113 D 208435 CDS NP_689027.1 22538176 1014852 2014978..2015841 1 NC_004116.1 identified by match to PFAM protein family HMM PF02517; protease 2015841 1014852 SAG2041 Streptococcus agalactiae 2603V/R protease NP_689027.1 2014978 D 208435 CDS NP_689028.1 22538177 1014853 complement(2015998..2016300) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00581; rhodanese-like domain-containing protein 2016300 1014853 SAG2042 Streptococcus agalactiae 2603V/R rhodanese-like domain-containing protein NP_689028.1 2015998 R 208435 CDS NP_689029.1 22538178 1014854 complement(2016473..2017240) 1 NC_004116.1 similar to SP:P09879; identified by sequence similarity; cAMP factor 2017240 cfb 1014854 cfb Streptococcus agalactiae 2603V/R cAMP factor NP_689029.1 2016473 R 208435 CDS NP_689030.1 22538179 1014855 complement(2017460..2017648) 1 NC_004116.1 hypothetical protein 2017648 1014855 SAG2044 Streptococcus agalactiae 2603V/R hypothetical protein NP_689030.1 2017460 R 208435 CDS NP_689031.1 22538180 1014856 2018009..2018548 1 NC_004116.1 topology modulation protein 2018548 1014856 SAG2045 Streptococcus agalactiae 2603V/R topology modulation protein NP_689031.1 2018009 D 208435 CDS NP_689032.1 22538181 1014857 2018749..2019834 1 NC_004116.1 identified by match to PFAM protein family HMM PF00465; glycerol dehydrogenase 2019834 1014857 SAG2046 Streptococcus agalactiae 2603V/R glycerol dehydrogenase NP_689032.1 2018749 D 208435 CDS NP_689033.1 22538182 1014858 complement(2019999..2020706) 1 NC_004116.1 hypothetical protein 2020706 1014858 SAG2047 Streptococcus agalactiae 2603V/R hypothetical protein NP_689033.1 2019999 R 208435 CDS NP_689034.1 22538183 1014859 complement(2021053..2022897) 1 NC_004116.1 catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine; expressed in B. subtilis under methionine starvation conditions; bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase 2022897 1014859 SAG2048 Streptococcus agalactiae 2603V/R bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase NP_689034.1 2021053 R 208435 CDS NP_689035.1 22538184 1014860 complement(2022942..2025179) 1 NC_004116.1 catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine to form methionine; 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase 2025179 metE 1014860 metE Streptococcus agalactiae 2603V/R 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase NP_689035.1 2022942 R 208435 CDS NP_689036.1 22538185 1014861 complement(2025549..2025872) 1 NC_004116.1 hypothetical protein 2025872 1014861 SAG2050 Streptococcus agalactiae 2603V/R hypothetical protein NP_689036.1 2025549 R 208435 CDS NP_689037.1 22538186 1014862 complement(2025862..2026554) 1 NC_004116.1 branched-chain amino acid transport protein AzlC 2026554 1014862 SAG2051 Streptococcus agalactiae 2603V/R branched-chain amino acid transport protein AzlC NP_689037.1 2025862 R 208435 CDS NP_689038.1 22538187 1014863 2026789..2026914 1 NC_004116.1 hypothetical protein 2026914 1014863 SAG2052 Streptococcus agalactiae 2603V/R hypothetical protein NP_689038.1 2026789 D 208435 CDS NP_689039.1 22538188 1014864 2026877..2031589 1 NC_004116.1 identified by match to PFAM protein family HMM PF00082; serine protease 2031589 1014864 SAG2053 Streptococcus agalactiae 2603V/R serine protease NP_689039.1 2026877 D 208435 CDS NP_689040.1 22538189 1014865 2031822..2032508 1 NC_004116.1 identified by match to PFAM protein family HMM PF00072; DNA-binding response regulator 2032508 1014865 SAG2054 Streptococcus agalactiae 2603V/R DNA-binding response regulator NP_689040.1 2031822 D 208435 CDS NP_689041.1 22538190 1014866 2032505..2033893 1 NC_004116.1 identified by match to PFAM protein family HMM PF00512; sensor histidine kinase 2033893 1014866 SAG2055 Streptococcus agalactiae 2603V/R sensor histidine kinase NP_689041.1 2032505 D 208435 CDS NP_689042.1 22538191 1014867 2033986..2034594 1 NC_004116.1 similar to OMNI:EF0852; identified by sequence similarity; hypothetical protein 2034594 1014867 SAG2056 Streptococcus agalactiae 2603V/R hypothetical protein NP_689042.1 2033986 D 208435 CDS NP_689043.1 22538192 1014868 complement(2034681..2037182) 1 NC_004116.1 leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase; leucyl-tRNA synthetase 2037182 leuS 1014868 leuS Streptococcus agalactiae 2603V/R leucyl-tRNA synthetase NP_689043.1 2034681 R 208435 CDS NP_689044.1 22538193 1014869 2037559..2038806 1 NC_004116.1 identified by match to PFAM protein family HMM PF00083; major facilitator family protein 2038806 1014869 SAG2058 Streptococcus agalactiae 2603V/R major facilitator family protein NP_689044.1 2037559 D 208435 CDS NP_689045.1 22538194 1014870 complement(2038849..2039694) 1 NC_004116.1 identified by match to PFAM protein family HMM PF01734; The product of this gene was detected by Western blot analysis. For details on the method see Tettelin et al. 2002.; hypothetical protein 2039694 1014870 SAG2059 Streptococcus agalactiae 2603V/R hypothetical protein NP_689045.1 2038849 R 208435 CDS NP_689046.1 22538195 1014871 2039899..2041095 1 NC_004116.1 identified by match to PFAM protein family HMM PF01501; glycosyl transferase family protein 2041095 1014871 SAG2060 Streptococcus agalactiae 2603V/R glycosyl transferase family protein NP_689046.1 2039899 D 208435 CDS NP_689047.1 22538196 1014872 2041160..2042365 1 NC_004116.1 identified by match to PFAM protein family HMM PF01501; glycosyl transferase family protein 2042365 1014872 SAG2061 Streptococcus agalactiae 2603V/R glycosyl transferase family protein NP_689047.1 2041160 D 208435 CDS NP_689048.1 22538197 1014873 complement(2042412..2042951) 1 NC_004116.1 Modulates Rho-dependent transcription termination; transcription antitermination protein NusG 2042951 nusG 1014873 nusG Streptococcus agalactiae 2603V/R transcription antitermination protein NusG NP_689048.1 2042412 R 208435 CDS NP_689049.1 22538198 1014874 complement(2043157..2045049) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00746; pathogenicity protein 2045049 1014874 SAG2063 Streptococcus agalactiae 2603V/R pathogenicity protein NP_689049.1 2043157 R 208435 CDS NP_689050.1 22538199 1014875 complement(2045361..2045534) 1 NC_004116.1 forms a complex with SecY and SecG; SecYEG forms a protein-conducting channel to which secA binds and translocates targeted polypeptides across the cytoplasmic membrane, a process driven by ATP and a proton-motive force; preprotein translocase subunit SecE 2045534 secE 1014875 secE Streptococcus agalactiae 2603V/R preprotein translocase subunit SecE NP_689050.1 2045361 R 208435 CDS NP_689051.1 22538200 1014876 complement(2045570..2045722) 1 NC_004116.1 in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group have the CXXC motif; 50S ribosomal protein L33 2045722 rpmG 1014876 rpmG Streptococcus agalactiae 2603V/R 50S ribosomal protein L33 NP_689051.1 2045570 R 208435 CDS NP_689052.1 22538201 1014877 complement(2045771..2048092) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00905; penicillin-binding protein 2A 2048092 pbp2A 1014877 pbp2A Streptococcus agalactiae 2603V/R penicillin-binding protein 2A NP_689052.1 2045771 R 208435 CDS NP_689053.1 22538202 1014878 2048136..2049020 1 NC_004116.1 identified by match to PFAM protein family HMM PF00849; ribosomal large subunit pseudouridine synthase D 2049020 1014878 SAG2067 Streptococcus agalactiae 2603V/R ribosomal large subunit pseudouridine synthase D NP_689053.1 2048136 D 208435 CDS NP_689054.1 22538203 1014879 complement(2049045..2050685) 1 NC_004116.1 hypothetical protein 2050685 1014879 SAG2068 Streptococcus agalactiae 2603V/R hypothetical protein NP_689054.1 2049045 R 208435 CDS NP_689055.1 22538204 1014880 complement(2050855..2052066) 1 NC_004116.1 catalyzes the transfer of phosphate between the C1 and C5 carbons of pentose; phosphopentomutase 2052066 deoB-2 1014880 deoB-2 Streptococcus agalactiae 2603V/R phosphopentomutase NP_689055.1 2050855 R 208435 CDS NP_689056.1 22538205 1014881 complement(2052133..2052804) 1 NC_004116.1 catalyzes the formation of D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-D-ribose-5-phosphate; deoxyribose-phosphate aldolase 2052804 deoC 1014881 deoC Streptococcus agalactiae 2603V/R deoxyribose-phosphate aldolase NP_689056.1 2052133 R 208435 CDS NP_689057.1 22538206 1014882 complement(2052834..2054036) 1 NC_004116.1 identified by match to PFAM protein family HMM PF01773; Na+ dependent nucleoside transporter 2054036 1014882 SAG2071 Streptococcus agalactiae 2603V/R Na+ dependent nucleoside transporter NP_689057.1 2052834 R 208435 CDS NP_689058.1 22538207 1014883 complement(2054057..2054836) 1 NC_004116.1 identified by match to PFAM protein family HMM PF01048; uridine phosphorylase 2054836 udp 1014883 udp Streptococcus agalactiae 2603V/R uridine phosphorylase NP_689058.1 2054057 R 208435 CDS NP_689059.1 22538208 1014884 2054994..2055731 1 NC_004116.1 identified by match to PFAM protein family HMM PF00392; GntR family transcriptional regulator 2055731 1014884 SAG2073 Streptococcus agalactiae 2603V/R GntR family transcriptional regulator NP_689059.1 2054994 D 208435 CDS YP_008592388.1 545902394 17097511 2055744..2056040 1 NC_004116.1 hypothetical protein 2056040 17097511 SAG_RS02460 Streptococcus agalactiae 2603V/R hypothetical protein YP_008592388.1 2055744 D 208435 CDS NP_689060.1 22538209 1014885 complement(2056140..2057762) 1 NC_004116.1 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth; molecular chaperone GroEL 2057762 groEL 1014885 groEL Streptococcus agalactiae 2603V/R molecular chaperone GroEL NP_689060.1 2056140 R 208435 CDS NP_689061.1 22538210 1014886 complement(2057858..2058142) 1 NC_004116.1 10 kDa chaperonin; Cpn10; GroES; forms homoheptameric ring; binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it; folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES; release of the folded substrate is dependent on ATP-binding and hydrolysis in the trans ring; co-chaperonin GroES 2058142 groES 1014886 groES Streptococcus agalactiae 2603V/R co-chaperonin GroES NP_689061.1 2057858 R 208435 CDS NP_689062.1 22538211 1014887 complement(2058317..2059120) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00005; ABC transporter ATP-binding protein 2059120 1014887 SAG2076 Streptococcus agalactiae 2603V/R ABC transporter ATP-binding protein NP_689062.1 2058317 R 208435 CDS NP_689063.1 22538212 1014888 complement(2059125..2060021) 1 NC_004116.1 identified by match to PFAM protein family HMM PF02653; ABC transporter permease 2060021 1014888 SAG2077 Streptococcus agalactiae 2603V/R ABC transporter permease NP_689063.1 2059125 R 208435 CDS NP_689064.1 22538213 1014889 complement(2060037..2060999) 1 NC_004116.1 similar to OMNI:SP1069; identified by sequence similarity; The product of this gene was detected by Western blot analysis. For details on the method see Tettelin et al. 2002.; hypothetical protein 2060999 1014889 SAG2078 Streptococcus agalactiae 2603V/R hypothetical protein NP_689064.1 2060037 R 208435 CDS NP_689065.1 22538214 1014890 complement(2061464..2062261) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00702; HAD superfamily hydrolase 2062261 1014890 SAG2079 Streptococcus agalactiae 2603V/R HAD superfamily hydrolase NP_689065.1 2061464 R 208435 CDS NP_689066.1 22538215 1014891 2062447..2063307 1 NC_004116.1 identified by match to PFAM protein family HMM PF00903; glyoxylase 2063307 1014891 SAG2080 Streptococcus agalactiae 2603V/R glyoxylase NP_689066.1 2062447 D 208435 CDS NP_689067.1 22538216 1014892 2063350..2064081 1 NC_004116.1 hypothetical protein 2064081 1014892 SAG2081 Streptococcus agalactiae 2603V/R hypothetical protein NP_689067.1 2063350 D 208435 CDS NP_689068.1 22538217 1014893 complement(2064438..2065055) 1 NC_004116.1 identified by match to PFAM protein family HMM PF02143; anaerobic ribonucleoside-triphosphate reductase activating protein 2065055 nrdG 1014893 nrdG Streptococcus agalactiae 2603V/R anaerobic ribonucleoside-triphosphate reductase activating protein NP_689068.1 2064438 R 208435 CDS NP_689069.1 22538218 1014894 complement(2065128..2065619) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00583; acetyltransferase 2065619 1014894 SAG2083 Streptococcus agalactiae 2603V/R acetyltransferase NP_689069.1 2065128 R 208435 CDS NP_689070.1 22538219 1014895 complement(2065628..2066560) 1 NC_004116.1 identified by match to PFAM protein family HMM PF01408; virulence factor MviM 2066560 1014895 SAG2084 Streptococcus agalactiae 2603V/R virulence factor MviM NP_689070.1 2065628 R 208435 CDS NP_689071.1 22538220 1014896 complement(2066573..2066716) 1 NC_004116.1 hypothetical protein 2066716 1014896 SAG2085 Streptococcus agalactiae 2603V/R hypothetical protein NP_689071.1 2066573 R 208435 CDS NP_689072.1 22538221 1014897 complement(2066791..2068962) 1 NC_004116.1 Catalyzes the reduction of nucleoside 5'-triphosphates to 2'-deoxynucleoside 5'-triphosphates; anaerobic ribonucleoside triphosphate reductase 2068962 nrdD 1014897 nrdD Streptococcus agalactiae 2603V/R anaerobic ribonucleoside triphosphate reductase NP_689072.1 2066791 R 208435 CDS NP_689073.1 22538222 1014898 complement(2069088..2070575) 1 NC_004116.1 similar to OMNI:NTL01SPL1648; identified by sequence similarity; hypothetical protein 2070575 1014898 SAG2087 Streptococcus agalactiae 2603V/R hypothetical protein NP_689073.1 2069088 R 208435 CDS NP_689074.1 22538223 1014899 complement(2070675..2070797) 1 NC_004116.1 hypothetical protein 2070797 1014899 SAG2088 Streptococcus agalactiae 2603V/R hypothetical protein NP_689074.1 2070675 R 208435 CDS NP_689075.1 22538224 1014900 complement(2070879..2071196) 1 NC_004116.1 hypothetical protein 2071196 1014900 SAG2089 Streptococcus agalactiae 2603V/R hypothetical protein NP_689075.1 2070879 R 208435 CDS NP_689076.1 22538225 1014901 complement(2071222..2071632) 1 NC_004116.1 similar to RuvC resolvase with substantial differences; NMR structural information suggests this protein is monomeric; unknown cellular function; Holliday junction resolvase-like protein 2071632 1014901 SAG2090 Streptococcus agalactiae 2603V/R Holliday junction resolvase-like protein NP_689076.1 2071222 R 208435 CDS NP_689077.1 22538226 1014902 complement(2071641..2071907) 1 NC_004116.1 hypothetical protein 2071907 1014902 SAG2091 Streptococcus agalactiae 2603V/R hypothetical protein NP_689077.1 2071641 R 208435 CDS NP_689078.1 22538227 1014903 complement(2072109..2072507) 1 NC_004116.1 the anti-alpha factor Spx interacts with RNA polymerase alpha subunit C-terminal domain in a region that interacts with the sigma 70 subunit and may interfere with activation of promoters; in Bacillus subtilis this protein is a substrate for ClpXP protease; blocks transcription of the competence regulatory gene encoded by the srf operon; regulates a number of genes involved in thiol homeostasis including trxA and trxB; monomeric member of ArsC family of proteins; does not bind DNA; contains a disulfide bond between C10 and C13 which may sense disulfide stress; Spx family transcriptional regulator 2072507 spxA 1014903 spxA Streptococcus agalactiae 2603V/R Spx family transcriptional regulator NP_689078.1 2072109 R 208435 CDS NP_689079.1 22538228 1014904 complement(2072723..2073862) 1 NC_004116.1 catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs; recombinase A 2073862 recA 1014904 recA Streptococcus agalactiae 2603V/R recombinase A NP_689079.1 2072723 R 208435 CDS NP_689080.1 22538229 1014906 complement(2075285..2075836) 1 NC_004116.1 identified by match to PFAM protein family HMM PF03352; DNA-3-methyladenine glycosylase I 2075836 tag 1014906 tag Streptococcus agalactiae 2603V/R DNA-3-methyladenine glycosylase I NP_689080.1 2075285 R 208435 CDS NP_689081.1 22538230 1014907 complement(2075859..2076449) 1 NC_004116.1 plays an essential role in ATP-dependent branch migration of the Holliday junction; Holliday junction DNA helicase RuvA 2076449 ruvA 1014907 ruvA Streptococcus agalactiae 2603V/R Holliday junction DNA helicase RuvA NP_689081.1 2075859 R 208435 CDS NP_689082.1 22538231 1014908 complement(2076451..2077707) 1 NC_004116.1 transporter 2077707 1014908 SAG2097 Streptococcus agalactiae 2603V/R transporter NP_689082.1 2076451 R 208435 CDS NP_689083.1 22538232 1014909 complement(2077715..2079694) 1 NC_004116.1 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. Promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex; DNA mismatch repair protein 2079694 mutL 1014909 mutL Streptococcus agalactiae 2603V/R DNA mismatch repair protein NP_689083.1 2077715 R 208435 CDS NP_689084.1 22538233 1014910 complement(2079819..2079920) 1 NC_004116.1 hypothetical protein 2079920 1014910 SAG2099 Streptococcus agalactiae 2603V/R hypothetical protein NP_689084.1 2079819 R 208435 CDS NP_689085.1 22538234 1014911 2079914..2080117 1 NC_004116.1 identified by match to PFAM protein family HMM PF00313; CSD family cold shock protein 2080117 1014911 SAG2100 Streptococcus agalactiae 2603V/R CSD family cold shock protein NP_689085.1 2079914 D 208435 CDS NP_689086.1 22538235 1014912 complement(2080174..2082750) 1 NC_004116.1 This protein performs the mismatch recognition step during the DNA repair process; DNA mismatch repair protein MutS 2082750 hexA 1014912 hexA Streptococcus agalactiae 2603V/R DNA mismatch repair protein MutS NP_689086.1 2080174 R 208435 CDS NP_689087.1 22538236 1014913 complement(2082807..2083244) 1 NC_004116.1 identified by match to PFAM protein family HMM PF01316; arginine repressor ArgR 2083244 1014913 SAG2102 Streptococcus agalactiae 2603V/R arginine repressor ArgR NP_689087.1 2082807 R 208435 CDS NP_689088.1 22538237 1014914 2083466..2085157 1 NC_004116.1 catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase; arginyl-tRNA synthetase 2085157 argS 1014914 argS Streptococcus agalactiae 2603V/R arginyl-tRNA synthetase NP_689088.1 2083466 D 208435 CDS NP_689089.1 22538238 1014915 2085245..2085553 1 NC_004116.1 hypothetical protein 2085553 1014915 SAG2104 Streptococcus agalactiae 2603V/R hypothetical protein NP_689089.1 2085245 D 208435 CDS NP_689090.1 22538239 1014916 complement(2085580..2086452) 1 NC_004116.1 hypothetical protein 2086452 1014916 SAG2105 Streptococcus agalactiae 2603V/R hypothetical protein NP_689090.1 2085580 R 208435 CDS NP_689091.1 22538240 1014917 complement(2086560..2087504) 1 NC_004116.1 hypothetical protein 2087504 1014917 SAG2106 Streptococcus agalactiae 2603V/R hypothetical protein NP_689091.1 2086560 R 208435 CDS NP_689092.1 22538241 1014918 complement(2087494..2089245) 1 NC_004116.1 catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes; aspartyl-tRNA synthetase 2089245 aspS 1014918 aspS Streptococcus agalactiae 2603V/R aspartyl-tRNA synthetase NP_689092.1 2087494 R 208435 CDS NP_689093.1 22538242 1014919 complement(2089338..2090618) 1 NC_004116.1 catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG; histidyl-tRNA synthetase 2090618 hisS 1014919 hisS Streptococcus agalactiae 2603V/R histidyl-tRNA synthetase NP_689093.1 2089338 R 208435 CDS NP_689094.1 22538243 1014920 2090838..2091020 1 NC_004116.1 some L32 proteins have zinc finger motifs consisting of CXXC while others do not; 50S ribosomal protein L32 2091020 rpmF 1014920 rpmF Streptococcus agalactiae 2603V/R 50S ribosomal protein L32 NP_689094.1 2090838 D 208435 CDS NP_689095.1 22538244 1014921 2091036..2091185 1 NC_004116.1 in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif; 50S ribosomal protein L33 2091185 rpmG 1014921 rpmG Streptococcus agalactiae 2603V/R 50S ribosomal protein L33 NP_689095.1 2091036 D 208435 CDS NP_689096.1 22538245 1014922 complement(2091333..2091854) 1 NC_004116.1 hypothetical protein 2091854 1014922 SAG2111 Streptococcus agalactiae 2603V/R hypothetical protein NP_689096.1 2091333 R 208435 CDS NP_689097.1 22538246 1014923 complement(2091952..2093436) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00589; phage integrase family site specific recombinase 2093436 1014923 SAG2112 Streptococcus agalactiae 2603V/R phage integrase family site specific recombinase NP_689097.1 2091952 R 208435 CDS NP_689098.1 22538247 1014924 complement(2093446..2093694) 1 NC_004116.1 hypothetical protein 2093694 1014924 SAG2113 Streptococcus agalactiae 2603V/R hypothetical protein NP_689098.1 2093446 R 208435 CDS NP_689099.1 22538248 1014925 complement(2093760..2094788) 1 NC_004116.1 hypothetical protein 2094788 1014925 SAG2114 Streptococcus agalactiae 2603V/R hypothetical protein NP_689099.1 2093760 R 208435 CDS NP_689100.1 22538249 1014926 complement(2094791..2095222) 1 NC_004116.1 hypothetical protein 2095222 1014926 SAG2115 Streptococcus agalactiae 2603V/R hypothetical protein NP_689100.1 2094791 R 208435 CDS NP_689101.1 22538250 1014927 complement(2095498..2095953) 1 NC_004116.1 hypothetical protein 2095953 1014927 SAG2116 Streptococcus agalactiae 2603V/R hypothetical protein NP_689101.1 2095498 R 208435 CDS NP_689102.1 22538251 1014928 complement(2095953..2096168) 1 NC_004116.1 hypothetical protein 2096168 1014928 SAG2117 Streptococcus agalactiae 2603V/R hypothetical protein NP_689102.1 2095953 R 208435 CDS NP_689103.1 22538252 1014929 2096491..2097411 1 NC_004116.1 identified by match to PFAM protein family HMM PF01381; The product of this gene was detected by Western blot analysis. For details on the method see Tettelin et al. 2002.; Cro/CI family transcriptional regulator 2097411 1014929 SAG2118 Streptococcus agalactiae 2603V/R Cro/CI family transcriptional regulator NP_689103.1 2096491 D 208435 CDS NP_689104.1 22538253 1014930 2097432..2098553 1 NC_004116.1 similar to GP:15161770; identified by sequence similarity; hypothetical protein 2098553 1014930 SAG2119 Streptococcus agalactiae 2603V/R hypothetical protein NP_689104.1 2097432 D 208435 CDS NP_689105.1 22538254 1014931 2098781..2099590 1 NC_004116.1 hypothetical protein 2099590 1014931 SAG2120 Streptococcus agalactiae 2603V/R hypothetical protein NP_689105.1 2098781 D 208435 CDS NP_689106.1 22538255 1014932 2100041..2100712 1 NC_004116.1 identified by Glimmer2; The product of this gene was detected by Western blot analysis. For details on the method see Tettelin et al. 2002.; hypothetical protein 2100712 1014932 SAG2121 Streptococcus agalactiae 2603V/R hypothetical protein NP_689106.1 2100041 D 208435 CDS NP_689107.1 22538256 1014933 2100797..2101468 1 NC_004116.1 identified by match to PFAM protein family HMM PF00072; DNA-binding response regulator 2101468 1014933 SAG2122 Streptococcus agalactiae 2603V/R DNA-binding response regulator NP_689107.1 2100797 D 208435 CDS NP_689108.1 22538257 1014934 2101452..2102816 1 NC_004116.1 identified by match to PFAM protein family HMM PF00512; sensor histidine kinase 2102816 1014934 SAG2123 Streptococcus agalactiae 2603V/R sensor histidine kinase NP_689108.1 2101452 D 208435 CDS NP_689109.1 22538258 1014935 complement(2102926..2104479) 1 NC_004116.1 hypothetical protein 2104479 1014935 SAG2124 Streptococcus agalactiae 2603V/R hypothetical protein NP_689109.1 2102926 R 208435 CDS NP_689110.1 22538259 1014936 complement(2104573..2105499) 1 NC_004116.1 catalyzes the reversible synthesis of carbamate and ATP from carbamoyl phosphate and ADP; carbamate kinase 2105499 arcC-1 1014936 arcC-1 Streptococcus agalactiae 2603V/R carbamate kinase NP_689110.1 2104573 R 208435 CDS NP_689111.1 22538260 1014937 complement(2105511..2106509) 1 NC_004116.1 catalyzes the formation of L-citrulline from carbamoyl phosphate and L-ornithine in arginine biosynthesis and degradation; ornithine carbamoyltransferase 2106509 argF-1 1014937 argF-1 Streptococcus agalactiae 2603V/R ornithine carbamoyltransferase NP_689111.1 2105511 R 208435 CDS NP_689112.1 22538261 1014938 2106612..2107907 1 NC_004116.1 identified by match to PFAM protein family HMM PF02518; sensor histidine kinase 2107907 1014938 SAG2127 Streptococcus agalactiae 2603V/R sensor histidine kinase NP_689112.1 2106612 D 208435 CDS NP_689113.1 22538262 1014939 2107904..2108737 1 NC_004116.1 identified by match to PFAM protein family HMM PF00072; response regulator 2108737 1014939 SAG2128 Streptococcus agalactiae 2603V/R response regulator NP_689113.1 2107904 D 208435 CDS NP_689114.1 22538263 1014940 2108959..2109681 1 NC_004116.1 identified by match to PFAM protein family HMM PF00005; amino acid ABC transporter ATP-binding protein 2109681 1014940 SAG2129 Streptococcus agalactiae 2603V/R amino acid ABC transporter ATP-binding protein NP_689114.1 2108959 D 208435 CDS NP_689115.1 22538264 1014941 2109684..2111198 1 NC_004116.1 identified by match to PFAM protein family HMM PF00528; amino acid ABC transporter amino acid-binding protein/permease 2111198 1014941 SAG2130 Streptococcus agalactiae 2603V/R amino acid ABC transporter amino acid-binding protein/permease NP_689115.1 2109684 D 208435 CDS NP_689116.1 22538265 1014942 complement(2111277..2113820) 1 NC_004116.1 hypothetical protein 2113820 1014942 SAG2131 Streptococcus agalactiae 2603V/R hypothetical protein NP_689116.1 2111277 R 208435 CDS NP_689117.1 22538266 1014943 complement(2113801..2114544) 1 NC_004116.1 hypothetical protein 2114544 1014943 SAG2132 Streptococcus agalactiae 2603V/R hypothetical protein NP_689117.1 2113801 R 208435 CDS NP_689118.1 22538267 1014944 complement(2114678..2115034) 1 NC_004116.1 hypothetical protein 2115034 1014944 SAG2133 Streptococcus agalactiae 2603V/R hypothetical protein NP_689118.1 2114678 R 208435 CDS NP_689119.1 22538268 1014945 complement(2115101..2117419) 1 NC_004116.1 similar to OMNI:NTL01SPL1699; identified by sequence similarity; hypothetical protein 2117419 1014945 SAG2134 Streptococcus agalactiae 2603V/R hypothetical protein NP_689119.1 2115101 R 208435 CDS NP_689120.1 22538269 1014946 2117558..2118097 1 NC_004116.1 TetR family transcriptional regulator 2118097 1014946 SAG2135 Streptococcus agalactiae 2603V/R TetR family transcriptional regulator NP_689120.1 2117558 D 208435 CDS NP_689121.1 22538270 1014947 complement(2118183..2118479) 1 NC_004116.1 hypothetical protein 2118479 1014947 SAG2136 Streptococcus agalactiae 2603V/R hypothetical protein NP_689121.1 2118183 R 208435 CDS NP_689122.1 22538271 1014948 complement(2118723..2119334) 1 NC_004116.1 primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination; 30S ribosomal protein S4 2119334 rpsD 1014948 rpsD Streptococcus agalactiae 2603V/R 30S ribosomal protein S4 NP_689122.1 2118723 R 208435 CDS NP_689123.1 22538272 1014949 complement(2119664..2119951) 1 NC_004116.1 hypothetical protein 2119951 1014949 SAG2138 Streptococcus agalactiae 2603V/R hypothetical protein NP_689123.1 2119664 R 208435 CDS NP_689124.1 22538273 1014950 complement(2119963..2121318) 1 NC_004116.1 unwinds double stranded DNA; replicative DNA helicase 2121318 dnaC-2 1014950 dnaC-2 Streptococcus agalactiae 2603V/R replicative DNA helicase NP_689124.1 2119963 R 208435 CDS NP_689125.1 22538274 1014951 complement(2121361..2121813) 1 NC_004116.1 in Escherichia coli this protein is wrapped around the base of the L1 stalk; 50S ribosomal protein L9 2121813 rplI 1014951 rplI Streptococcus agalactiae 2603V/R 50S ribosomal protein L9 NP_689125.1 2121361 R 208435 CDS NP_689126.1 22538275 1014952 complement(2121819..2123801) 1 NC_004116.1 identified by match to PFAM protein family HMM PF01368; The product of this gene was detected by Western blot analysis. For details on the method see Tettelin et al. 2002.; DHH family protein 2123801 1014952 SAG2141 Streptococcus agalactiae 2603V/R DHH family protein NP_689126.1 2121819 R 208435 CDS NP_689127.1 22538276 1014953 complement(2123868..2125709) 1 NC_004116.1 GidA; glucose-inhibited cell division protein A; involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U) of the wobble uridine base in some tRNAs; tRNA uridine 5-carboxymethylaminomethyl modification protein GidA 2125709 gidA 1014953 gidA Streptococcus agalactiae 2603V/R tRNA uridine 5-carboxymethylaminomethyl modification protein GidA NP_689127.1 2123868 R 208435 CDS NP_689128.1 22538277 1014954 complement(2125938..2126549) 1 NC_004116.1 identified by match to PFAM protein family HMM PF01914; hypothetical protein 2126549 1014954 SAG2143 Streptococcus agalactiae 2603V/R hypothetical protein NP_689128.1 2125938 R 208435 CDS NP_689129.1 22538278 1014955 complement(2126581..2127702) 1 NC_004116.1 catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs; tRNA-specific 2-thiouridylase MnmA 2127702 mnmA 1014955 mnmA Streptococcus agalactiae 2603V/R tRNA-specific 2-thiouridylase MnmA NP_689129.1 2126581 R 208435 CDS NP_689130.1 22538279 1014956 2127948..2128616 1 NC_004116.1 identified by match to PFAM protein family HMM PF01842; L-serine dehydratase, iron-sulfur-dependent subunit beta 2128616 sdhB 1014956 sdhB Streptococcus agalactiae 2603V/R L-serine dehydratase, iron-sulfur-dependent subunit beta NP_689130.1 2127948 D 208435 CDS NP_689131.1 22538280 1014957 2128631..2129503 1 NC_004116.1 identified by match to PFAM protein family HMM PF03313; L-serine dehydratase, iron-sulfur-dependent subunit alpha 2129503 sdhA 1014957 sdhA Streptococcus agalactiae 2603V/R L-serine dehydratase, iron-sulfur-dependent subunit alpha NP_689131.1 2128631 D 208435 CDS NP_689132.1 22538281 1014958 complement(2129638..2130342) 1 NC_004116.1 similar to OMNI:NTL01SPL1712; identified by sequence similarity; The product of this gene was detected by Western blot analysis. For details on the method see Tettelin et al. 2002.; hypothetical protein 2130342 1014958 SAG2147 Streptococcus agalactiae 2603V/R hypothetical protein NP_689132.1 2129638 R 208435 CDS NP_689133.1 22538282 1014959 complement(2130448..2130987) 1 NC_004116.1 identified by match to PFAM protein family HMM PF01476; LysM domain-containing protein 2130987 1014959 SAG2148 Streptococcus agalactiae 2603V/R LysM domain-containing protein NP_689133.1 2130448 R 208435 CDS NP_689134.1 22538283 1014960 complement(2131203..2131997) 1 NC_004116.1 identified by match to PFAM protein family HMM PF02361; cobalt transport family protein 2131997 1014960 SAG2149 Streptococcus agalactiae 2603V/R cobalt transport family protein NP_689134.1 2131203 R 208435 CDS NP_689135.1 22538284 1014961 complement(2131990..2132832) 1 NC_004116.1 with CbiNQ forms the ABC transporter for cobalt import; Streptococcus has two adjacent copies of this gene; cobalt transporter ATP-binding subunit 2132832 cbiO 1014961 cbiO Streptococcus agalactiae 2603V/R cobalt transporter ATP-binding subunit NP_689135.1 2131990 R 208435 CDS NP_689136.1 22538285 1014962 complement(2132808..2133647) 1 NC_004116.1 with CbiNQ forms the ABC transporter for cobalt import; Streptococcus has two adjacent copies of this gene; cobalt transporter ATP-binding subunit 2133647 cbiO 1014962 cbiO Streptococcus agalactiae 2603V/R cobalt transporter ATP-binding subunit NP_689136.1 2132808 R 208435 CDS NP_689137.1 22538286 1014963 complement(2133647..2134189) 1 NC_004116.1 identified by match to PFAM protein family HMM PF01066; CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase 2134189 pgsA 1014963 pgsA Streptococcus agalactiae 2603V/R CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase NP_689137.1 2133647 R 208435 CDS NP_689138.1 22538287 1014964 complement(2134312..2135595) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00675; M16 family peptidase 2135595 1014964 SAG2153 Streptococcus agalactiae 2603V/R M16 family peptidase NP_689138.1 2134312 R 208435 CDS NP_689139.1 22538288 1014965 complement(2135597..2136841) 1 NC_004116.1 hypothetical protein 2136841 1014965 SAG2154 Streptococcus agalactiae 2603V/R hypothetical protein NP_689139.1 2135597 R 208435 CDS NP_689140.1 22538289 1014966 2137080..2137433 1 NC_004116.1 hypothetical protein 2137433 1014966 SAG2155 Streptococcus agalactiae 2603V/R hypothetical protein NP_689140.1 2137080 D 208435 CDS NP_689141.1 22538290 1014967 2137436..2138545 1 NC_004116.1 Required for DNA replication; binds preferentially to single-stranded, linear DNA; recombination protein F 2138545 recF 1014967 recF Streptococcus agalactiae 2603V/R recombination protein F NP_689141.1 2137436 D 208435 CDS NP_689142.1 22538291 1014968 complement(2138557..2139393) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00892; transporter 2139393 1014968 SAG2157 Streptococcus agalactiae 2603V/R transporter NP_689142.1 2138557 R 208435 CDS NP_689143.1 22538292 1014969 complement(2139479..2140141) 1 NC_004116.1 identified by match to PFAM protein family HMM PF01381; Cro/CI family transcriptional regulator 2140141 1014969 SAG2158 Streptococcus agalactiae 2603V/R Cro/CI family transcriptional regulator NP_689143.1 2139479 R 208435 CDS NP_689144.1 22538293 1014970 complement(2140216..2141697) 1 NC_004116.1 catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate; inosine 5'-monophosphate dehydrogenase 2141697 guaB 1014970 guaB Streptococcus agalactiae 2603V/R inosine 5'-monophosphate dehydrogenase NP_689144.1 2140216 R 208435 CDS NP_689145.1 22538294 1014971 complement(2141854..2142339) 1 NC_004116.1 identified by match to PFAM protein family HMM PF02863; ArgR family transcriptional regulator 2142339 1014971 SAG2160 Streptococcus agalactiae 2603V/R ArgR family transcriptional regulator NP_689145.1 2141854 R 208435 CDS NP_689146.1 22538295 1014972 complement(2142349..2143029) 1 NC_004116.1 identified by match to PFAM protein family HMM PF00027; Crp/Fnr family transcriptional regulator 2143029 1014972 SAG2161 Streptococcus agalactiae 2603V/R Crp/Fnr family transcriptional regulator NP_689146.1 2142349 R 208435 CDS NP_689147.1 22538296 1014973 2143237..2143941 1 NC_004116.1 hypothetical protein 2143941 1014973 SAG2162 Streptococcus agalactiae 2603V/R hypothetical protein NP_689147.1 2143237 D 208435 CDS NP_689148.1 22538297 1014974 2144208..2145440 1 NC_004116.1 catalyzes the degradation of arginine to citruline and ammonia; arginine deiminase 2145440 arcA 1014974 arcA Streptococcus agalactiae 2603V/R arginine deiminase NP_689148.1 2144208 D 208435 CDS NP_689149.1 22538298 1014975 2145467..2145877 1 NC_004116.1 identified by match to PFAM protein family HMM PF00583; acetyltransferase 2145877 1014975 SAG2164 Streptococcus agalactiae 2603V/R acetyltransferase NP_689149.1 2145467 D 208435 CDS NP_689150.1 22538299 1014976 2145893..2146906 1 NC_004116.1 catalyzes the formation of ornithine and carbamylphosphate from citrulline in the arginine catabolic pathway; ornithine carbamoyltransferase 2146906 argF-2 1014976 argF-2 Streptococcus agalactiae 2603V/R ornithine carbamoyltransferase NP_689150.1 2145893 D 208435 CDS NP_689151.1 22538300 1014977 2146969..2148396 1 NC_004116.1 identified by match to PFAM protein family HMM PF00324; arginine/ornithine antiporter 2148396 arcD 1014977 arcD Streptococcus agalactiae 2603V/R arginine/ornithine antiporter NP_689151.1 2146969 D 208435 CDS NP_689152.1 22538301 1014978 2148417..2149373 1 NC_004116.1 catalyzes the reversible synthesis of carbamate and ATP from carbamoyl phosphate and ADP; carbamate kinase 2149373 arcC-2 1014978 arcC-2 Streptococcus agalactiae 2603V/R carbamate kinase NP_689152.1 2148417 D 208435 CDS NP_689153.1 22538302 1014979 complement(2149483..2150508) 1 NC_004116.1 catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; tryptophanyl-tRNA synthetase 2150508 trpS 1014979 trpS Streptococcus agalactiae 2603V/R tryptophanyl-tRNA synthetase NP_689153.1 2149483 R 208435 CDS NP_689154.1 22538303 1014980 complement(2150616..2151308) 1 NC_004116.1 hypothetical protein 2151308 1014980 SAG2169 Streptococcus agalactiae 2603V/R hypothetical protein NP_689154.1 2150616 R 208435 CDS NP_689155.1 22538304 1014981 2151552..2152424 1 NC_004116.1 hypothetical protein 2152424 1014981 SAG2170 Streptococcus agalactiae 2603V/R hypothetical protein NP_689155.1 2151552 D 208435 CDS NP_689156.1 22538305 1014982 2152490..2154109 1 NC_004116.1 identified by match to PFAM protein family HMM PF00005; ABC transporter ATP-binding protein 2154109 1014982 SAG2171 Streptococcus agalactiae 2603V/R ABC transporter ATP-binding protein NP_689156.1 2152490 D 208435 CDS NP_689157.1 22538306 1014983 2154232..2156811 1 NC_004116.1 similar to OMNI:NTL01SPL1730; identified by sequence similarity; hypothetical protein 2156811 1014983 SAG2172 Streptococcus agalactiae 2603V/R hypothetical protein NP_689157.1 2154232 D 208435 CDS NP_689158.1 22538307 1014987 complement(2157390..2157869) 1 NC_004116.1 SPOUT methyltransferase family protein; crystal structure shows homodimer; in Escherichia coli this protein methylates pseudouridine at position 1915 of the 23S ribosomal RNA; rRNA large subunit methyltransferase 2157869 1014987 SAG2173 Streptococcus agalactiae 2603V/R rRNA large subunit methyltransferase NP_689158.1 2157390 R 208435 CDS NP_689159.1 22538308 1014988 2158070..2159299 1 NC_004116.1 identified by match to PFAM protein family HMM PF00089; serine protease 2159299 1014988 SAG2174 Streptococcus agalactiae 2603V/R serine protease NP_689159.1 2158070 D 208435 CDS NP_689160.1 22538309 1014989 2159397..2160170 1 NC_004116.1 identified by match to PFAM protein family HMM PF02195; ParB family partitioning protein 2160170 1014989 SAG2175 Streptococcus agalactiae 2603V/R ParB family partitioning protein NP_689160.1 2159397 D 208435 CDS