-- dump date 20140620_081034 -- class Genbank::CDS -- table cds_note -- id note NP_687037.1 binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication; can also affect transcription of multiple genes including itself. NP_687038.1 binds the polymerase to DNA and acts as a sliding clamp NP_687039.1 identified by match to PFAM protein family HMM PF00781 NP_687042.1 translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1 NP_687043.1 Enables the recycling of peptidyl-tRNAs produced at termination of translation NP_687044.1 identified by match to PFAM protein family HMM PF00270 NP_687046.1 identified by match to PFAM protein family HMM PF01479 NP_687047.1 similar to OMNI:NTL01SPL0011; identified by sequence similarity NP_687049.1 The product of this gene was detected by Western blot analysis. For details on the method see Tettelin et al. 2002. NP_687051.1 Catalyzes the salvage synthesis of inosine-5'-monophosphate (IMP) and guanosine-5'-monophosphate (GMP) from the purine bases hypoxanthine and guanine, respectively NP_687052.1 identified by match to PFAM protein family HMM PF00004 NP_687053.1 similar to GP:12667037; identified by sequence similarity NP_687054.1 catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP NP_687055.1 catalyzes the transamination of the aromatic amino acid forming a ketoacid; first step in aromatic amino acid degradation in lactococci NP_687056.1 involved in DNA repair and RecFOR pathway recombination; RecFOR proteins displace ssDNA-binding protein and facilitate the production of RecA-coated ssDNA NP_687057.1 identified by match to PFAM protein family HMM PF02517 NP_687058.1 involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsY NP_687059.1 carries the fatty acid chain in fatty acid biosynthesis NP_687060.1 catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis; SAICAR synthase NP_687061.1 identified by match to PFAM protein family HMM PF02769 NP_687062.1 Catalyzes first step of the de novo purine nucleotide biosynthetic pathway NP_687063.1 catalyzes the formation of 1-(5-phosphoribosyl)-5-aminoimidazole from 2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in purine biosynthesis NP_687064.1 glycinamide ribonucleotide transformylase; GAR Tfase; catalyzes the synthesis of 5'-phosphoribosylformylglycinamide from 5'-phosphoribosylglycinamide and 10-formyltetrahydrofolate; PurN requires formyl folate for the reaction unlike PurT which uses formate NP_687065.1 identified by match to PFAM protein family HMM PF00583 NP_687066.1 involved in de novo purine biosynthesis NP_687067.1 identified by match to PFAM protein family HMM PF01551 NP_687068.1 identified by match to PFAM protein family HMM PF01476 NP_687069.1 Converts N-acetylmannosamine-6-phosphate to N-acetylglucosamine-6-phosphate NP_687070.1 identified by match to PFAM protein family HMM PF01547 NP_687071.1 identified by match to PFAM protein family HMM PF00528 NP_687072.1 identified by match to PFAM protein family HMM PF00528 NP_687075.1 identified by match to PFAM protein family HMM PF00701 NP_687076.1 identified by match to PFAM protein family HMM PF00480; The product of this gene was detected by Western blot analysis. For details on the method see Tettelin et al. 2002. NP_687078.1 identified by match to PFAM protein family HMM PF01380 NP_687079.1 catalyzes the formation of N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-D-ribosylamine and glycine in purine biosynthesis NP_687080.1 Catalyzes a step in the de novo purine nucleotide biosynthetic pathway NP_687081.1 With PurE catalyzes the conversion of aminoimidazole ribonucleotide to carboxyaminoimidazole ribonucleotide in the de novo purine nucleotide biosynthetic pathway NP_687083.1 Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide NP_687084.1 identified by match to PFAM protein family HMM PF01381 NP_687085.1 promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration NP_687086.1 identified by match to PFAM protein family HMM PF01451 NP_687087.1 identified by match to PFAM protein family HMM PF02493 NP_687088.1 identified by match to PFAM protein family HMM PF01757 NP_687089.1 identified by match to PFAM protein family HMM PF00171 NP_687090.1 similar to zinc-dependent eukaryotic ADH enzymes and distinct from fermentative ADHs NP_687091.1 catalyzes the formation of L-threonine from O-phospho-L-homoserine NP_687092.1 identified by match to PFAM protein family HMM PF01554 NP_687093.1 NusE; involved in assembly of the 30S subunit; in the ribosome, this protein is involved in the binding of tRNA; in Escherichia coli this protein was also found to be involved in transcription antitermination; NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination; binding of NusB/S10 to boxA nucleates assembly of the antitermination complex NP_687094.1 binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin NP_687095.1 L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA NP_687096.1 binds third domain of 23S rRNA and protein L29; part of exit tunnel NP_687097.1 one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation NP_687098.1 protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA NP_687099.1 binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center NP_687100.1 forms a complex with S10 and S14; binds the lower part of the 30S subunit head and the mRNA in the complete ribosome to position it for translation NP_687101.1 located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e NP_687102.1 one of the stabilizing components for the large ribosomal subunit NP_687103.1 primary binding protein; helps mediate assembly; involved in translation fidelity NP_687104.1 binds to the 23S rRNA between the centers for peptidyl transferase and GTPase NP_687105.1 assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel NP_687106.1 part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13 NP_687107.1 located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group appear to contain the zinc-binding motif NP_687108.1 binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit NP_687109.1 ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance NP_687110.1 binds 5S rRNA along with protein L5 and L25 NP_687111.1 located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance NP_687112.1 L30 binds domain II of the 23S rRNA and the 5S rRNA; similar to eukaryotic protein L7 NP_687113.1 late assembly protein NP_687114.1 forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase NP_687115.1 essential enzyme that recycles AMP in active cells; converts ATP and AMP to two molecules of ADP NP_687116.1 stimulates the activities of the other two initiation factors, IF-2 and IF-3 NP_687117.1 smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group have the motif NP_687118.1 located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA NP_687119.2 located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3 NP_687120.1 catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme NP_687121.1 is a component of the macrolide binding site in the peptidyl transferase center NP_687127.1 similar to OMNI:SP0014; identified by sequence similarity NP_687128.1 identified by match to PFAM protein family HMM PF00300 NP_687129.1 identified by match to PFAM protein family HMM PF02557 NP_687130.1 identified by match to PFAM protein family HMM PF01832 NP_687131.1 Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons NP_687132.1 with DnaK and DnaJ acts in response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins; may act as a thermosensor NP_687133.1 heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria NP_687134.1 chaperone Hsp40; co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion NP_687135.1 identified by match to PFAM protein family HMM PF00392 NP_687136.1 mediates pseudouridylation (positions 38, 39, 40) at the tRNA anticodon region which contributes to the structural stability NP_687137.1 catalyzes the formation of 4-amino-2-methyl-5-diphosphomethylpyrimidine NP_687141.1 Tig; RopA; peptidyl-prolyl cis/trans isomerase; promotes folding of newly synthesized proteins; binds ribosomal 50S subunit; forms a homodimer NP_687142.1 participates in both the initiation and recycling phases of transcription; in the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling NP_687143.1 CTP synthase; CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer NP_687145.1 catalyzes the formation of dUMP from dUTP NP_687146.1 Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents NP_687148.1 Involved in disulfide oxidoreductase activity and electron transport NP_687149.1 Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation NP_687150.1 identified by match to PFAM protein family HMM PF00532 NP_687151.1 identified by match to PFAM protein family HMM PF02653 NP_687152.1 identified by match to PFAM protein family HMM PF00005 NP_687153.1 cytoplasmic mutarotase that catalyzes the conversion between beta-pyran and beta-furan forms of D-ribose; RbsD is required for efficient ribose utilization in E. coli; rbsD-mutant E. coli strains are unable to use ribose as a sole carbon source NP_687154.1 identified by match to PFAM protein family HMM PF00294 NP_687155.1 identified by match to PFAM protein family HMM PF00356 NP_687157.1 identified by match to PFAM protein family HMM PF02687 NP_687158.1 identified by match to PFAM protein family HMM PF00005 NP_687159.1 identified by match to PFAM protein family HMM PF00072 NP_687160.1 identified by match to PFAM protein family HMM PF00512 NP_687161.1 catalyzes the formation of 2-N(omega)-(L-arginino)succinate from L-citrulline and L-aspartate in arginine biosynthesis, AMP-forming NP_687162.1 catalyzes the formation of arginine from (N-L-arginino)succinate NP_687163.1 catalyzes the formation of glycerone phosphate and glyceraldehyde 3-phosphate from fructose 1,6, bisphosphate NP_687164.1 identified by match to PFAM protein family HMM PF00056 NP_687165.1 required for 70S ribosome assembly NP_687167.1 identified by match to PFAM protein family HMM PF02734 NP_687168.1 identified by match to PFAM protein family HMM PF01145; The product of this gene was detected by Western blot analysis. For details on the method see Tettelin et al. 2002. NP_687171.1 identified by match to PFAM protein family HMM PF00005 NP_687172.1 identified by match to PFAM protein family HMM PF00497 NP_687174.1 BacA; phosphatase activity in Escherichia coli not kinase; involved in bacitracin resistance as bacitracin supposedly sequesters undecaprenyl disphosphate which reduces the pool of lipid carrier available to the cell NP_687175.1 enables recognition and targeting of proteins for proteolysis, involved in negative regulation of competence NP_687176.1 identified by match to PFAM protein family HMM PF00953 NP_687177.1 identified by match to PFAM protein family HMM PF00005 NP_687179.1 identified by match to PFAM protein family HMM PF00266 NP_687180.1 identified by match to PFAM protein family HMM PF01592 NP_687182.1 identified by match to PFAM protein family HMM PF00768 NP_687183.1 identified by match to PFAM protein family HMM PF00768 NP_687184.1 identified by match to PFAM protein family HMM PF00496 NP_687185.1 identified by match to PFAM protein family HMM PF00528 NP_687186.1 identified by match to PFAM protein family HMM PF00528 NP_687187.1 identified by match to PFAM protein family HMM PF00005 NP_687188.1 identified by match to PFAM protein family HMM PF00005 NP_687189.1 An essential enzyme in the nonmevalonate pathway of isopentenyl diphosphate and dimethylallyl diphosphate biosynthesis NP_687190.1 identified by match to PFAM protein family HMM PF01047 NP_687191.1 identified by match to PFAM protein family HMM PF00005 NP_687192.1 identified by match to PFAM protein family HMM PF00950 NP_687193.1 catalyzes the formation of tyrosyl-tRNA(Tyr) from tyrosine and tRNA(Tyr) NP_687194.1 identified by match to PFAM protein family HMM PF00905 NP_687195.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme NP_687196.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Subunit beta' binds to sigma factor allowing it to bind to the -10 region of the promoter NP_687198.1 identified by match to PFAM protein family HMM PF00437 NP_687199.1 identified by match to PFAM protein family HMM PF00482 NP_687201.1 similar to OMNI:NTL01SPL0084; identified by sequence similarity NP_687203.1 AckA utilizes acetate and can acetylate CheY which increases signal strength during flagellar rotation; utilizes magnesium and ATP; also involved in conversion of acetate to aceyl-CoA NP_687204.1 identified by match to PFAM protein family HMM PF01381 NP_687207.1 identified by match to PFAM protein family HMM PF02517 NP_687208.1 catalyzes the formation of L-proline from pyrroline-5-carboxylate NP_687209.1 similar to PID:1072381; identified by sequence similarity NP_687212.1 identified by match to PFAM protein family HMM PF00085 NP_687213.1 identified by match to PFAM protein family HMM PF01588 NP_687215.1 binds to single stranded DNA and may facilitate the binding and interaction of other proteins to DNA NP_687216.1 identified by match to PFAM protein family HMM PF00702 NP_687217.1 identified by match to PFAM protein family HMM PF02518 NP_687218.1 identified by match to PFAM protein family HMM PF00072 NP_687222.1 identified by match to PFAM protein family HMM PF00496 NP_687223.1 identified by match to PFAM protein family HMM PF00528 NP_687224.1 identified by match to PFAM protein family HMM PF00528 NP_687225.1 identified by match to PFAM protein family HMM PF00005 NP_687226.1 identified by match to PFAM protein family HMM PF00005 NP_687227.1 identified by match to PFAM protein family HMM PF00358 NP_687228.1 identified by match to PFAM protein family HMM PF00128 NP_687229.1 identified by match to PFAM protein family HMM PF00359 NP_687230.1 identified by match to PFAM protein family HMM PF01609 NP_687231.1 similar to OMNI:SP2131; identified by sequence similarity NP_687232.1 similar to OMNI:SP2130; identified by sequence similarity NP_687233.1 membrane component; functions with enzymes IIB (sgaB; ulaB) and IIA (sgaA; ulaC) enzyme I and HPr for anaerobic utilization and uptake of L-ascorbate; sgaTBA are regulated by yifQ as well as Crp and Fnr NP_687234.1 identified by match to PFAM protein family HMM PF00456 NP_687235.1 identified by match to PFAM protein family HMM PF02779 NP_687236.1 identified by match to PFAM protein family HMM PF00175 NP_687237.1 primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence NP_687238.1 identified by match to PFAM protein family HMM PF00013 NP_687240.1 identified by match to PFAM protein family HMM PF00132 NP_687242.1 catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA NP_687244.1 identified by match to PFAM protein family HMM PF00588 NP_687246.1 identified by match to PFAM protein family HMM PF02645 NP_687249.1 in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit NP_687250.1 forms a direct contact with the tRNA during translation NP_687252.1 identified by match to PFAM protein family HMM PF00589 NP_687253.1 identified by match to PFAM protein family HMM PF01381 NP_687257.1 similar to OMNI:EFC0001; identified by sequence similarity NP_687259.1 identified by match to PFAM protein family HMM PF02486 NP_687261.1 identified by match to PFAM protein family HMM PF01076 NP_687276.1 identified by match to PFAM protein family HMM PF00528 NP_687277.1 similar to GB:AL009126; identified by sequence similarity NP_687278.1 identified by match to PFAM protein family HMM PF00528 NP_687279.1 identified by match to PFAM protein family HMM PF00005 NP_687280.1 identified by Glimmer2; The product of this gene was detected by Western blot analysis. For details on the method see Tettelin et al. 2002. NP_687286.1 identified by match to PFAM protein family HMM PF01381 NP_687287.1 identified by match to PFAM protein family HMM PF00583 NP_687288.1 identified by match to PFAM protein family HMM PF00583 NP_687289.1 identified by match to PFAM protein family HMM PF00583 NP_687291.1 identified by match to PFAM protein family HMM PF00776 NP_687293.1 identified by match to PFAM protein family HMM PF00440 NP_687295.1 identified by match to PFAM protein family HMM PF00005 NP_687296.1 identified by match to PFAM protein family HMM PF01609 NP_687297.1 similar to OMNI:SP0537; identified by sequence similarity NP_687300.1 identified by Glimmer2; The product of this gene was detected by Western blot analysis. For details on the method see Tettelin et al. 2002. NP_687301.1 identified by match to PFAM protein family HMM PF02612 NP_687303.1 glycine--tRNA ligase alpha chain; GlyRS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA NP_687305.1 glycine--tRNA ligase beta chain; glyS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA NP_687307.1 similar to OMNI:NTL01SPL1075; identified by sequence similarity NP_687308.1 Converts glycerol and ADP to glycerol-3-phosphate and ADP NP_687309.1 identified by match to PFAM protein family HMM PF01224 NP_687310.1 identified by match to PFAM protein family HMM PF00230 NP_687311.1 identified by match to PFAM protein family HMM PF00070 NP_687313.1 catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase NP_687315.1 identified by match to PFAM protein family HMM PF00005 NP_687316.1 similar to OMNI:NTL01SPL1317; identified by sequence similarity NP_687317.1 identified by match to PFAM protein family HMM PF00367 NP_687318.1 catalyzes the formation of glutamate 5-phosphate from glutamate in proline biosynthesis NP_687319.1 Catalyzes the phosphorylation of L-glutamate during the proline biosynthesis pathway NP_687321.1 similar to OMNI:SP0335; identified by sequence similarity NP_687322.1 identified by match to PFAM protein family HMM PF00905 NP_687323.1 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan NP_687324.1 identified by match to PFAM protein family HMM PF00270 NP_687325.1 identified by match to PFAM protein family HMM PF00497 NP_687326.1 identified by match to PFAM protein family HMM PF00528 NP_687327.1 identified by match to PFAM protein family HMM PF00005 NP_687329.1 identified by match to PFAM protein family HMM PF00070 NP_687330.1 catalyzes the formation of 5-phospho-alpha-D-ribose 1-diphosphate and nicotinate from nicotinate D-ribonucleotide and diphosphate NP_687331.1 catalyzes the formation of nicotinamide adenine dinucleotide (NAD) from nicotinic acid adenine dinucleotide (NAAD) using either ammonia or glutamine as the amide donor and ATP; ammonia-utilizing enzymes include the ones from Bacillus and Escherichia coli while glutamine-utilizing enzymes include the Mycobacterial one; forms homodimers NP_687332.1 identified by match to PFAM protein family HMM PF03051 NP_687333.1 identified by match to PFAM protein family HMM PF00905 NP_687334.1 functions in homologous recombination, DNA repair, and chromosome segregation; binds preferentially to three- and four-stranded DNA intermediates; introduces specific nick sites in four-stranded DNA substrates; functions similarly to Escherichia coli RuvC NP_687337.1 GpsB; guiding PBP1 shuttling; similar to DivIVA NP_687340.1 catalyzes the hydrolysis of S-ribosylhomocysteine to homocysteine and autoinducer-2 NP_687341.1 identified by match to PFAM protein family HMM PF00013 NP_687343.1 identified by match to PFAM protein family HMM PF00005 NP_687347.1 Essential for recycling GMP and indirectly, cGMP NP_687348.1 Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits NP_687349.1 binding of PriA to forked DNA starts the assembly of the primosome, also possesses 3'-5' helicase activity NP_687350.1 modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet) which is important in translation initiation; inactivation of this gene in Escherichia coli severely impairs growth NP_687351.1 identified by match to PFAM protein family HMM PF01029 NP_687352.1 identified by match to PFAM protein family HMM PF00481 NP_687353.1 identified by match to PFAM protein family HMM PF00069 NP_687355.1 identified by match to PFAM protein family HMM PF02518 NP_687356.1 identified by match to PFAM protein family HMM PF00072 NP_687357.1 identified by match to PFAM protein family HMM PF00160 NP_687358.1 identified by match to PFAM protein family HMM PF00575 NP_687359.1 identified by match to PFAM protein family HMM PF02143 NP_687360.1 identified by match to PFAM protein family HMM PF00455 NP_687362.1 identified by match to PFAM protein family HMM PF02255 NP_687363.1 identified by match to PFAM protein family HMM PF02302 NP_687364.1 identified by match to PFAM protein family HMM PF02378 NP_687365.1 identified by match to PFAM protein family HMM PF01228 NP_687366.1 similar to transaldolase from Escherichia coli; many organisms have multiple copies NP_687367.1 forms dimers and octamers; involved in conversion of glycerol to dihydroxy-acetone NP_687368.1 identified by match to PFAM protein family HMM PF00291 NP_687370.1 identified by match to PFAM protein family HMM PF00270 NP_687372.1 identified by match to PFAM protein family HMM PF02482 NP_687373.1 catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP; lysine and threonine sensitive NP_687374.1 identified by match to PFAM protein family HMM PF00702 NP_687376.1 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA NP_687377.1 identified by match to PFAM protein family HMM PF01047 NP_687378.1 FabH; beta-ketoacyl-acyl carrier protein synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs NP_687379.1 carries the fatty acid chain in fatty acid biosynthesis NP_687380.1 identified by match to PFAM protein family HMM PF03060 NP_687381.1 identified by match to PFAM protein family HMM PF00698 NP_687382.1 catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis NP_687383.1 FabF; beta-ketoacyl-ACP synthase II, KASII; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP NP_687384.1 composes the biotin carboxyl carrier protein subunit of the acetyl-CoA carboxylase complex, the enzyme that catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, which in turn controls the rate of fatty acid metabolism NP_687385.1 in Pseudomonas aeruginosa this enzyme is a trimer of dimers; essential for membrane formation; performs third step of type II fatty acid biosynthesis; catalyzes dehydration of (3R)-hydroxyacyl-ACP to trans-2-acyl-ACP NP_687386.1 an AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism NP_687387.1 catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer of AccA2D2 subunits NP_687388.1 catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer composed of two alpha (AccA) and two beta (AccD) subunits; one of the two catalytic subunits that can form the acetyl CoA carboxylase enzyme together with a carrier protein; these proteins present a shorter N-terminus NP_687390.1 catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA NP_687396.1 identified by match to PFAM protein family HMM PF00702 NP_687398.1 similar to GB:AE000520; identified by sequence similarity NP_687399.1 identified by match to PFAM protein family HMM PF00860 NP_687401.1 identified by match to PFAM protein family HMM PF00583 NP_687402.1 identified by match to TIGR protein family HMM TIGR00350; The product of this gene was detected by Western blot analysis. For details on the method see Tettelin et al. 2002. NP_687404.1 identified by match to PFAM protein family HMM PF01230 NP_687407.1 identified by match to PFAM protein family HMM PF00005 NP_687408.1 similar to OMNI:NTL01SPL1360; identified by sequence similarity NP_687410.1 tRNA (guanine-N(7)-)-methyltransferase; catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA by transferring the methyl residue from S-adenosyl-L-methionine NP_687411.1 in Streptococcus pneumoniae this gene was found to be essential; structure determination of the Streptococcus protein shows that it is similar to a number of other proteins NP_687412.2 modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination NP_687414.1 identified by match to PFAM protein family HMM PF01248 NP_687415.1 Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex NP_687416.1 associates with free 30S ribosomal subunits; essential for efficient processing of 16S rRNA; in Escherichia coli rbfA is induced by cold shock NP_687417.1 similar to OMNI:NTL01SPL1351; identified by sequence similarity; The product of this gene was detected by Western blot analysis. For details on the method see Tettelin et al. 2002. NP_687419.1 identified by match to PFAM protein family HMM PF00122 NP_687420.1 identified by match to PFAM protein family HMM PF00403 NP_687421.1 identified by match to PFAM protein family HMM PF03458 NP_687422.1 identified by match to PFAM protein family HMM PF00702 NP_687423.1 has 3'-5' exonuclease, 5'-3' exonuclease and 5'-3'polymerase activities, primarily functions to fill gaps during DNA replication and repair NP_687424.1 identified by match to PFAM protein family HMM PF02629 NP_687425.1 identified by match to PFAM protein family HMM PF01475 NP_687426.1 identified by match to PFAM protein family HMM PF00746; The product of this gene was detected by Western blot analysis. For details on the method see Tettelin et al. 2002. NP_687427.1 identified by match to PFAM protein family HMM PF00072 NP_687428.1 identified by match to PFAM protein family HMM PF00512 NP_687429.1 similar to OMNI:NTL01SPL0158; identified by sequence similarity NP_687430.1 Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr) NP_687432.1 identified by match to PFAM protein family HMM PF02632 NP_687434.1 identified by match to PFAM protein family HMM PF00383 NP_687436.1 functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis; catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate; member of PGI family NP_687437.1 identified by match to PFAM protein family HMM PF01812 NP_687438.1 identified by match to PFAM protein family HMM PF01694 NP_687439.1 identified by match to PFAM protein family HMM PF02608; The product of this gene was detected by Western blot analysis. For details on the method see Tettelin et al. 2002. NP_687440.1 identified by match to PFAM protein family HMM PF00483 NP_687441.1 catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate NP_687442.1 protein component of RNaseP which catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'terminus; this enzyme also cleaves other RNA substrates NP_687443.1 identified by match to PFAM protein family HMM PF02096 NP_687444.1 identified by match to PFAM protein family HMM PF01424 NP_687446.1 binds RecA and inhibits RecA-mediated DNA strand exchange and ATP hydrolysis and coprotease activities NP_687447.1 identified by match to PFAM protein family HMM PF01938 NP_687449.1 identified by match to PFAM protein family HMM PF00583 NP_687450.1 identified by match to PFAM protein family HMM PF00082; The product of this gene was detected by Western blot analysis. For details on the method see Tettelin et al. 2002. NP_687451.1 identified by match to PFAM protein family HMM PF00535 NP_687452.1 B2 or R2 protein; type 1b enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdE NP_687453.1 in Salmonella NrdI has a stimulatory effect on the ribonucleotide reductase activity of NrdH with NrdEF NP_687454.1 Catalyzes the rate-limiting step in dNTP synthesis NP_687455.1 similar to OMNI:NTL01SPL0643; identified by sequence similarity; There are documented cases with S in place of G in the LPXTG motif. The product of this gene was detected by Western blot analysis. For details on the method see Tettelin et al. 2002. NP_687457.1 similar to OMNI:NTL01CA0427; identified by sequence similarity NP_687459.1 identified by match to PFAM protein family HMM PF02627 NP_687461.1 identified by match to PFAM protein family HMM PF00376 NP_687462.1 identified by match to PFAM protein family HMM PF00107 NP_687463.1 identified by match to PFAM protein family HMM PF00248 NP_687464.1 identified by match to PFAM protein family HMM PF01545 NP_687465.1 identified by match to PFAM protein family HMM PF00440 NP_687466.1 identified by match to PFAM protein family HMM PF00165 NP_687467.1 identified by match to PFAM protein family HMM PF00746 NP_687468.1 similar to PID:984582 GB:U00096 SP:Q47150 PID:1786420; identified by sequence similarity NP_687472.1 similar to GP:13622655; identified by sequence similarity NP_687473.1 identified by match to PFAM protein family HMM PF00583 NP_687474.1 identified by match to PFAM protein family HMM PF00583 NP_687476.1 valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain NP_687477.1 identified by match to PFAM protein family HMM PF01408 NP_687478.1 identified by match to PFAM protein family HMM PF01544 NP_687479.1 identified by match to PFAM protein family HMM PF00872 NP_687481.1 catalyzes the formation of asparagine from aspartate and ammonia NP_687483.1 identified by match to TIGR protein family HMM TIGR00095 NP_687485.1 Catalyzes the conversion of ATP and pantetheine 4'-phosphate to diphosphate and 3'-dephospho-coA NP_687488.1 23S rRNA m2A2503 methyltransferase; methylates the C2 position of the A2530 nucleotide in 23S rRNA; may be involved in antibiotic resistance NP_687489.1 similar to OMNI:SP0769; identified by sequence similarity NP_687490.1 identified by match to PFAM protein family HMM PF00005 NP_687491.1 identified by match to PFAM protein family HMM PF00005 NP_687492.1 TrpG; with TrpE catalyzes the formation of anthranilate and glutamate from chorismate and glutamine; TrpG provides the glutamine amidotransferase activity NP_687493.1 identified by match to PFAM protein family HMM PF02632 NP_687494.1 identified by match to PFAM protein family HMM PF01792 NP_687496.1 identified by match to PFAM protein family HMM PF00108 NP_687498.1 identified by match to PFAM protein family HMM PF00730 NP_687499.1 similar to OMNI:SP1808; identified by sequence similarity NP_687501.1 identified by match to PFAM protein family HMM PF00480 NP_687502.1 identified by match to PFAM protein family HMM PF00581; The product of this gene was detected by Western blot analysis. For details on the method see Tettelin et al. 2002. NP_687503.1 identified by match to PFAM protein family HMM PF00009 NP_687505.1 UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation NP_687506.1 UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; involved in cell wall formation; inner membrane-associated; last step of peptidoglycan synthesis NP_687507.1 similar to OMNI:SP0690; identified by sequence similarity NP_687508.1 identified by match to PFAM protein family HMM PF02491 NP_687509.1 GTPase; similar structure to tubulin; forms ring-shaped polymers at the site of cell division; other proteins such as FtsA, ZipA, and ZapA, interact with and regulate FtsZ function NP_687510.1 identified by match to PFAM protein family HMM PF01168 NP_687511.1 similar to GP:4009494; identified by sequence similarity NP_687512.1 identified by match to PFAM protein family HMM PF02325 NP_687513.1 identified by match to PFAM protein family HMM PF01479 NP_687514.1 similar to OMNI:SP1661; identified by sequence similarity NP_687515.1 IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase family; some organisms carry two different copies of this enzyme NP_687517.1 identified by match to PFAM protein family HMM PF00293 NP_687518.1 identified by match to PFAM protein family HMM PF00004 NP_687521.1 identified by match to PFAM protein family HMM PF00528 NP_687522.1 identified by match to PFAM protein family HMM PF00005 NP_687523.1 identified by match to PFAM protein family HMM PF00408 NP_687524.1 catalyzes the formation of 5,10-methenyltetrahydrofolate from 5,10-methylenetetrahydrofolate and subsequent formation of 10-formyltetrahydrofolate from 5,10-methenyltetrahydrofolate NP_687525.1 identified by match to PFAM protein family HMM PF01256; The product of this gene was detected by Western blot analysis. For details on the method see Tettelin et al. 2002. NP_687526.1 bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides NP_687527.1 catalyzes the bidirectional exonucleolytic cleavage of DNA NP_687528.1 identified by match to PFAM protein family HMM PF00348 NP_687529.1 identified by match to PFAM protein family HMM PF01479 NP_687530.1 identified by match to PFAM protein family HMM PF01316 NP_687531.1 identified by match to PFAM protein family HMM PF02463 NP_687532.1 identified by match to PFAM protein family HMM PF02645; The product of this gene was detected by Western blot analysis. For details on the method see Tettelin et al. 2002. NP_687533.1 identified by match to PFAM protein family HMM PF00657; The product of this gene was detected by Western blot analysis. For details on the method see Tettelin et al. 2002. NP_687535.1 identified by match to PFAM protein family HMM PF00216 NP_687537.1 catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway; subclass 1A is a dimer formed by two identical PyrD subunits each containing an FMN group NP_687538.1 identified by match to PFAM protein family HMM PF02388 NP_687539.1 identified by match to PFAM protein family HMM PF02388 NP_687540.1 identified by match to PFAM protein family HMM PF02388 NP_687541.1 identified by match to PFAM protein family HMM PF00702 NP_687542.1 identified by match to PFAM protein family HMM PF01966 NP_687544.1 identified by match to PFAM protein family HMM PF00122 NP_687546.1 similar to PID:1064791 GB:AL009126; identified by sequence similarity NP_687547.1 identified by match to PFAM protein family HMM PF00037 NP_687548.1 identified by match to PFAM protein family HMM PF00005 NP_687549.1 identified by match to PFAM protein family HMM PF02687 NP_687550.1 similar to OMNI:EF0274; identified by sequence similarity NP_687551.1 identified by match to PFAM protein family HMM PF00753 NP_687552.1 identified by match to PFAM protein family HMM PF00106 NP_687553.1 unwinds DNA NP_687554.1 catalyzes the formation of oxalozcetate and L-glutamate from L-aspartate and 2-oxoglutarate NP_687555.1 catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA NP_687557.1 identified by match to PFAM protein family HMM PF01156 NP_687559.1 identified by match to PFAM protein family HMM PF02566 NP_687563.1 similar to OMNI:NTL01LL1596; identified by sequence similarity NP_687564.1 identified by match to PFAM protein family HMM PF01297 NP_687565.1 RpmE2; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster do not have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome NP_687566.1 identified by match to PFAM protein family HMM PF01368 NP_687567.1 catalyzes the formation of inosine from adenosine NP_687568.1 An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group NP_687569.1 identified by match to PFAM protein family HMM PF01817 NP_687570.1 identified by match to PFAM protein family HMM PF00654 NP_687571.1 similar to OMNI:SP0537; identified by sequence similarity NP_687572.1 identified by match to PFAM protein family HMM PF01609 NP_687573.1 this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site NP_687574.1 identified by match to PFAM protein family HMM PF00589 NP_687575.1 similar to GP:2444082; identified by sequence similarity NP_687577.1 identified by match to PFAM protein family HMM PF00717 NP_687583.1 identified by match to PFAM protein family HMM PF01381 NP_687594.1 similar to GP:8918764; identified by sequence similarity NP_687595.1 identified by match to PFAM protein family HMM PF00436 NP_687596.1 identified by match to PFAM protein family HMM PF00078 NP_687614.1 similar to PID:1353548; identified by sequence similarity NP_687620.1 similar to PID:1353554; identified by sequence similarity NP_687623.1 similar to GP:10732857; identified by sequence similarity NP_687624.1 similar to GP:3540285; identified by sequence similarity NP_687625.1 identified by match to PFAM protein family HMM PF01832 NP_687626.1 similar to GP:3540290; identified by sequence similarity NP_687631.1 similar to GP:1934766; identified by sequence similarity NP_687638.1 identified by match to PFAM protein family HMM PF02687 NP_687639.1 identified by match to PFAM protein family HMM PF00005 NP_687640.1 identified by match to PFAM protein family HMM PF02687 NP_687641.1 identified by match to PFAM protein family HMM PF00072 NP_687642.1 identified by match to PFAM protein family HMM PF00512 NP_687645.1 identified by match to PFAM protein family HMM PF01098 NP_687646.1 identified by match to PFAM protein family HMM PF00702 NP_687647.1 negatively supercoils closed circular double-stranded DNA NP_687648.1 acts to negatively regulates ftsZ ring formation by modulating the frequency and position of the ftsZ ring formation NP_687649.1 identified by match to PFAM protein family HMM PF00702 NP_687650.1 identified by match to PFAM protein family HMM PF00293 NP_687652.1 enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis NP_687653.1 similar to OMNI:NTL01SPL0534; identified by sequence similarity NP_687654.1 catalyzes the formation of 5-O-(1-carboxyvinyl)-3-phosphoshikimate from phosphoenolpyruvate and 3-phosphoshikimate in tryptophan biosynthesis NP_687655.1 catalyzes the formation of shikimate 3-phosphate from shikimate in aromatic amino acid biosynthesis NP_687656.1 identified by match to TIGR protein family HMM TIGR00350 NP_687657.1 identified by match to PFAM protein family HMM PF01938 NP_687659.1 Class B; non-specific; catalyzes the dephosphorylation of organic phosphomonoesters; also has phosphotransferase activity NP_687661.1 identified by match to PFAM protein family HMM PF00665 NP_687662.1 identified by match to PFAM protein family HMM PF01527 NP_687664.1 identified by match to PFAM protein family HMM PF00165 NP_687665.1 identified by match to PFAM protein family HMM PF00746; The product of this gene was detected by Western blot analysis. For details on the method see Tettelin et al. 2002. NP_687666.1 identified by match to TIGR protein family HMM TIGR01167; The product of this gene was detected by Western blot analysis. For details on the method see Tettelin et al. 2002. NP_687667.1 identified by match to TIGR protein family HMM TIGR01076 NP_687668.1 identified by match to TIGR protein family HMM TIGR01076 NP_687669.1 similar to OMNI:SP0462; identified by sequence similarity; The product of this gene was detected by Western blot analysis. For details on the method see Tettelin et al. 2002. NP_687670.1 identified by match to TIGR protein family HMM TIGR01076 NP_687671.1 identified by Glimmer2; The product of this gene was detected by Western blot analysis. For details on the method see Tettelin et al. 2002. NP_687676.1 similar to OMNI:EF0746; identified by sequence similarity NP_687677.1 identified by match to PFAM protein family HMM PF00005 NP_687678.1 similar to OMNI:SP0637; identified by sequence similarity NP_687680.1 similar to GP:4886770; identified by sequence similarity NP_687682.1 identified by match to PFAM protein family HMM PF00106 NP_687684.1 identified by match to PFAM protein family HMM PF01377 NP_687685.1 identified by match to PFAM protein family HMM PF00005 NP_687687.1 similar to GP:4886777; identified by sequence similarity NP_687688.1 identified by match to PFAM protein family HMM PF01571 NP_687689.1 identified by match to PFAM protein family HMM PF00109 NP_687690.1 similar to GP:6007854; identified by sequence similarity NP_687691.1 similar to GP:6007855; identified by sequence similarity NP_687693.1 similar to SP:P16952; identified by sequence similarity NP_687694.1 identified by match to PFAM protein family HMM PF00082 NP_687695.1 identified by Glimmer2; The product of this gene was detected by Western blot analysis. For details on the method see Tettelin et al. 2002. NP_687696.1 The product of this gene was detected by Western blot analysis. For details on the method see Tettelin et al. 2002. NP_687697.1 The product of this gene was detected by Western blot analysis. For details on the method see Tettelin et al. 2002. NP_687699.1 identified by match to PFAM protein family HMM PF02687 NP_687700.1 identified by match to PFAM protein family HMM PF00005 NP_687702.1 similar to SP:Q03158 GB:X54225 PID:47374; identified by sequence similarity NP_687703.1 identified by match to PFAM protein family HMM PF00597 NP_687704.1 identified by match to PFAM protein family HMM PF00005 NP_687705.1 identified by match to TIGR protein family HMM TIGR00245 NP_687707.1 identified by match to PFAM protein family HMM PF00126 NP_687708.1 similar to GP:5901699; identified by sequence similarity NP_687709.1 identified by match to PFAM protein family HMM PF01609 NP_687710.1 catalyzes the formation of pyruvate from lactate NP_687712.1 identified by match to PFAM protein family HMM PF00294 NP_687713.1 identified by match to PFAM protein family HMM PF00703 NP_687714.1 identified by match to PFAM protein family HMM PF00392 NP_687715.1 identified by match to PFAM protein family HMM PF01081 NP_687716.1 catalyzes the interconversion of D-glucuronate to D-fructuronate or D-galacturonate to D-tagaturonate; functions in glucuronic and galacturonic metabolism NP_687717.1 catalyzes the formation of 2-dehydro-3-deoxy-D-gluconate from mannonate NP_687718.1 Converts D-mannonate to D-mannuronate NP_687719.1 identified by match to PFAM protein family HMM PF00702 NP_687720.1 identified by match to PFAM protein family HMM PF00933 NP_687721.1 identified by match to PFAM protein family HMM PF00557 NP_687722.1 identified by match to PFAM protein family HMM PF00356 NP_687723.1 converts 1,4-alpha-D-glucans to maltodextrin NP_687724.1 identified by match to PFAM protein family HMM PF00534 NP_687725.1 identified by match to PFAM protein family HMM PF00534 NP_687726.1 catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr) NP_687727.1 identified by match to PFAM protein family HMM PF00072 NP_687730.1 identified by match to PFAM protein family HMM PF00528 NP_687731.1 identified by match to PFAM protein family HMM PF00528 NP_687732.1 identified by match to PFAM protein family HMM PF00497 NP_687733.1 identified by match to PFAM protein family HMM PF00005 NP_687734.1 identified by match to PFAM protein family HMM PF00072 NP_687735.1 identified by match to PFAM protein family HMM PF00512 NP_687736.1 identified by match to PFAM protein family HMM PF00753 NP_687738.1 cytoplasmic enzyme involved in processing rRNA and some mRNAs; substrates typically have dsRNA regions; forms a homodimer; have N-terminal nuclease and C-terminal RNA-binding domains; requires magnesium as preferred ion for activity NP_687739.1 identified by match to PFAM protein family HMM PF02463; The product of this gene was detected by Western blot analysis. For details on the method see Tettelin et al. 2002. NP_687740.1 identified by match to PFAM protein family HMM PF00702 NP_687741.1 identified by match to PFAM protein family HMM PF00702 NP_687742.1 identified by match to PFAM protein family HMM PF00448 NP_687743.1 similar to OMNI:NTL01SPL0427; identified by sequence similarity NP_687744.1 similar to OMNI:NTL01SPL0428; identified by sequence similarity NP_687745.1 similar to OMNI:NTL01SPL0429; identified by sequence similarity NP_687746.1 identified by match to PFAM protein family HMM PF00296 NP_687747.1 identified by match to PFAM protein family HMM PF00575 NP_687749.1 similar to SP:P23855 GB:X57560 PID:42541 GB:U00096 PID:1742136; identified by sequence similarity NP_687751.1 catalyzes the phosphorylation of the phosphocarrier protein HPr of the bacterial phosphotransferase system NP_687752.1 transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein NP_687757.1 identified by match to PFAM protein family HMM PF01136 NP_687760.1 identified by match to PFAM protein family HMM PF01566 NP_687761.1 identified by match to PFAM protein family HMM PF00383 NP_687762.2 catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine NP_687763.1 identified by match to PFAM protein family HMM PF00925 NP_687764.1 RibE; 6,7-diimethyl-8-ribityllumazine synthase; DMRL synthase; lumazine synthase; beta subunit of riboflavin synthase; condenses 5-amino-6-(1'-D)-ribityl-amino-2,4(1H,3H)-pyrimidinedione with L-3,4-dihydrohy-2-butanone-4-phosphate to generate 6,6-dimethyl-8-lumazine (DMRL); riboflavin synthase then uses 2 molecules of DMRL to produce riboflavin (vitamin B12); involved in the last steps of riboflavin biosynthesis; forms a 60mer (icosahedral shell) in both Bacillus subtilis and Escherichia coli; in Bacillus subtilis this 60mer is associated with the riboflavin synthase subunit (alpha) while in Escherichia coli it is not NP_687765.1 class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1 NP_687766.1 identified by match to PFAM protein family HMM PF00702 NP_687767.1 identified by match to PFAM protein family HMM PF00300 NP_687770.1 similar to OMNI:NTL01SPL0447; identified by sequence similarity NP_687772.1 similar to GP:13621804; identified by sequence similarity; The product of this gene was detected by Western blot analysis. For details on the method see Tettelin et al. 2002. NP_687773.1 identified by match to PFAM protein family HMM PF01432 NP_687774.1 catalyzes the formation of oxaloacetate from phosphoenolpyruvate NP_687775.1 identified by match to PFAM protein family HMM PF01609 NP_687776.1 identified by match to PFAM protein family HMM PF01098 NP_687777.1 EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu NP_687778.1 Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate NP_687779.1 2,3-bisphosphoglycerate-dependent; catalyzes the interconversion of 2-phosphoglycerate to 3-phosphoglycerate NP_687780.1 identified by match to PFAM protein family HMM PF00905 NP_687781.1 involved in a recombinational process of DNA repair, independent of the recBC complex NP_687782.1 D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli NP_687783.1 identified by match to PFAM protein family HMM PF01225 NP_687784.1 identified by match to PFAM protein family HMM PF00083 NP_687785.1 similar to OMNI:SP1668; identified by sequence similarity NP_687786.1 identified by match to TIGR protein family HMM TIGR01167 NP_687787.1 stimulates the release of release factors 1 and 2 from the ribosome after hydrolysis of the ester bond in peptidyl-tRNA has occurred; GDP/GTP-binding protein NP_687789.1 identified by match to PFAM protein family HMM PF00005 NP_687790.1 identified by match to PFAM protein family HMM PF00528 NP_687791.1 identified by match to PFAM protein family HMM PF03180 NP_687792.1 identified by match to PFAM protein family HMM PF00270 NP_687795.1 identified by match to PFAM protein family HMM PF01553 NP_687796.1 identified by match to PFAM protein family HMM PF00633 NP_687797.1 identified by match to PFAM protein family HMM PF00753 NP_687798.1 identified by match to PFAM protein family HMM PF00702 NP_687799.1 identified by match to PFAM protein family HMM PF00356 NP_687802.1 required for the assembly and function of the DNAX complex which is required for the assembly of the beta subunit onto primed DNA NP_687803.1 identified by match to PFAM protein family HMM PF00081 NP_687804.1 identified by match to PFAM protein family HMM PF00874 NP_687805.1 identified by match to PFAM protein family HMM PF00358 NP_687806.1 identified by match to PFAM protein family HMM PF00232 NP_687808.1 identified by match to PFAM protein family HMM PF02595; The product of this gene was detected by Western blot analysis. For details on the method see Tettelin et al. 2002. NP_687809.1 identified by match to PFAM protein family HMM PF02447 NP_687811.1 identified by match to PFAM protein family HMM PF01047 NP_687812.1 Synthesizes oQ from preQ1 in a single S-adenosylmethionine-requiring step NP_687814.1 identified by match to PFAM protein family HMM PF01182 NP_687815.1 identified by match to PFAM protein family HMM PF00043 NP_687816.1 identified by match to PFAM protein family HMM PF00849 NP_687818.1 identified by match to PFAM protein family HMM PF00083 NP_687819.1 similar to OMNI:SP0978; identified by sequence similarity NP_687820.1 identified by match to PFAM protein family HMM PF01432 NP_687821.1 identified by match to PFAM protein family HMM PF00702 NP_687822.1 identified by match to PFAM protein family HMM PF01596 NP_687823.1 cis/trans isomerase of peptidylprolyl; PPIase; membrane-bound lipoprotein NP_687825.1 Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA NP_687826.1 similar to OMNI:NTL01BH4061; identified by sequence similarity NP_687827.1 identified by match to PFAM protein family HMM PF01501 NP_687830.1 identified by match to PFAM protein family HMM PF01381 NP_687831.1 similar to OMNI:NTL01SPL1088; identified by sequence similarity NP_687832.1 similar to OMNI:NTL01SPL0446; identified by sequence similarity NP_687833.1 B2 or R2 protein; type 1b enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdE NP_687834.1 Catalyzes the rate-limiting step in dNTP synthesis NP_687836.1 identified by match to PFAM protein family HMM PF00381 NP_687837.1 identified by match to PFAM protein family HMM PF00391 NP_687838.1 identified by match to PFAM protein family HMM PF00171 NP_687839.1 identified by match to PFAM protein family HMM PF01522 NP_687840.1 identified by match to PFAM protein family HMM PF00270 NP_687841.1 functions in pyrimidine salvage; pyrimidine ribonucleoside kinase; phosphorylates nucleosides or dinucleosides to make UMP or CMP using ATP or GTP as the donor NP_687843.1 catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the tau chain serves as a scaffold to help in the dimerizaton of the alpha,epsilon and theta core complex; the gamma chain seems to interact with the delta and delta' subunits to transfer the beta subunit on the DNA NP_687845.1 catalyzes the formation of biotinyl-5'-AMP, also acts as a transcriptional repressor of the biotin operon NP_687846.1 methionine adenosyltransferase; catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase NP_687847.1 identified by Glimmer2; The product of this gene was detected by Western blot analysis. For details on the method see Tettelin et al. 2002. NP_687852.1 identified by match to PFAM protein family HMM PF00005 NP_687854.1 identified by match to PFAM protein family HMM PF03070 NP_687855.1 catalyzes the formation of 4-amino-2-methyl-5-diphosphomethylpyrimidine NP_687856.1 catalyzes the formation of 4-methyl-5-(2-phosphoethyl)-thiazole and ADP from 4-methyl-5-(2-hydroxyethyl)-thiazole and ATP NP_687857.1 Condenses 4-methyl-5-(beta-hydroxyethyl)-thiazole monophosphate and 4-amino-5-hydroxymethyl pyrimidine pyrophosphate to form thiamine monophosphate NP_687858.1 adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active NP_687859.1 identified by match to PFAM protein family HMM PF00583 NP_687860.1 identified by match to PFAM protein family HMM PF00571 NP_687861.1 catalyzes the removal of N-terminal amino acids from peptides and arylamides NP_687862.1 identified by match to TIGR protein family HMM TIGR00765 NP_687863.1 similar to GB:X73124 SP:P39602 PID:413958 GB:AL009126; identified by sequence similarity NP_687865.1 this protein catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction; essential for DNA replication and repair of damaged DNA; similar to ligase LigB NP_687866.1 similar to YegS from E. coli NP_687867.1 identified by match to PFAM protein family HMM PF00128 NP_687868.1 catalyzes the transfer of a segment of a 1,4-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain NP_687869.1 catalyzes the formation of ADP-glucose and diphosphate from ATP and alpha-D-glucose 1-phosphate NP_687870.1 catalyzes the formation of alpha-1,4-glucan chains from ADP-glucose NP_687871.1 produces ATP from ADP in the presence of a proton gradient across the membrane; subunit C is part of the membrane proton channel F0 NP_687872.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0 NP_687873.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit B is part of the membrane proton channel. NP_687874.1 Produces ATP from ADP in the presence of a proton gradient across the membrane; the delta subunit is part of the catalytic core of the ATP synthase complex NP_687875.1 produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit NP_687876.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is a regulatory subunit NP_687877.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit NP_687878.1 part of catalytic core of ATP synthase; alpha(3)beta(3)gamma(1)delta(1)epsilon(1); involved in producing ATP from ADP in the presence of the proton motive force across the membrane NP_687880.1 adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active NP_687882.1 identified by match to PFAM protein family HMM PF01223 NP_687883.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily NP_687884.1 identified by match to PFAM protein family HMM PF00583 NP_687885.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily NP_687887.1 similar to GP:2909715; identified by sequence similarity; RexAB system found in Gram positive bacteria appears to fulfill the biological roles of RecBCD found in Gram negative bacteria. NP_687888.1 identified by match to PFAM protein family HMM PF00580; RexAB system found in Gram positive bacteria appears to fulfill the biological roles of RecBCD found in Gram negative bacteria. NP_687889.1 identified by match to PFAM protein family HMM PF01544 NP_687890.1 in Escherichia coli this protein is involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2-thiouridine, which is found in the wobble position of some tRNAs and affects ribosomal frameshifting; shows potassium-dependent dimerization and GTP hydrolysis; also involved in regulation of glutamate-dependent acid resistance and activation of gadE NP_687891.1 identified by match to PFAM protein family HMM PF00005 NP_687892.1 identified by match to PFAM protein family HMM PF00676 NP_687893.1 identified by match to PFAM protein family HMM PF02779 NP_687894.1 Catalyzes the transfer of acetyl from acetyldihydrolipoamide to coenzyme A to form acetyl CoA NP_687895.1 identified by match to PFAM protein family HMM PF00070 NP_687896.1 identified by match to PFAM protein family HMM PF02539 NP_687897.1 similar to OMNI:NTL01LL1120; identified by sequence similarity NP_687900.1 The product of this gene was detected by Western blot analysis. For details on the method see Tettelin et al. 2002. NP_687901.1 catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate NP_687904.1 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III NP_687906.1 identified by match to PFAM protein family HMM PF00702 NP_687908.1 similar to OMNI:NTL01SPL0811; identified by sequence similarity; The product of this gene was detected by Western blot analysis. For details on the method see Tettelin et al. 2002. NP_687910.1 similar to OMNI:NTL01SPL0813; identified by sequence similarity NP_687919.1 catalyzes the formation of nucleoside triphosphate from ATP and nucleoside diphosphate NP_687920.1 binds to the ribosome on the universally-conserved alpha-sarcin loop NP_687921.1 identified by match to PFAM protein family HMM PF00560; The product of this gene was detected by Western blot analysis. For details on the method see Tettelin et al. 2002. NP_687922.1 identified by match to PFAM protein family HMM PF01966 NP_687923.1 identified by match to PFAM protein family HMM PF00583 NP_687924.1 this stereospecific enzymes reduces the R isomer of methionine sulfoxide while MsrA reduces the S form; provides protection against oxidative stress NP_687925.1 identified by match to PFAM protein family HMM PF00122 NP_687927.1 identified by match to PFAM protein family HMM PF00132 NP_687929.1 identified by match to PFAM protein family HMM PF00589 NP_687930.1 similar to SP:P27452 GB:S56948 GB:X61025 PID:47462; identified by sequence similarity NP_687935.1 identified by match to PFAM protein family HMM PF01381 NP_687937.1 identified by match to PFAM protein family HMM PF00009 NP_687938.1 regulates the transcription of tet(M) by attenuation NP_687940.1 identified by match to PFAM protein family HMM PF00877 NP_687945.1 identified by match to PFAM protein family HMM PF01381 NP_687946.1 identified by match to PFAM protein family HMM PF01580 NP_687950.1 identified by match to PFAM protein family HMM PF00392 NP_687951.1 Catalyzes DNA-template-directed extension of the 3'-end of a DNA strand by one nucleotide at a time. Proposed to be responsible for the synthesis of the lagging strand. In the low GC gram positive bacteria this enzyme is less processive and more error prone than its counterpart in other bacteria. NP_687952.1 catalyzes the formation of D-fructose 1,6-bisphosphate from D-fructose 6-phosphate in glycolysis NP_687953.1 catalyzes the formation of phosphoenolpyruvate from pyruvate NP_687954.1 identified by match to PFAM protein family HMM PF00461 NP_687956.1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source NP_687957.1 identified by match to PFAM protein family HMM PF01609 NP_687958.1 identified by match to TIGR protein family HMM TIGR00686 NP_687959.1 identified by match to PFAM protein family HMM PF00528 NP_687960.1 identified by match to PFAM protein family HMM PF00005 NP_687961.1 identified by match to PFAM protein family HMM PF00497 NP_687962.2 binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase NP_687963.1 catalyzes the formation of (R)-4'-phosphopantothenate in coenzyme A biosynthesis NP_687965.1 Reclaims exogenous and endogenous cytidine and 2'-deoxycytidine molecules for UMP synthesis NP_687966.1 identified by match to PFAM protein family HMM PF02608; The product of this gene was detected by Western blot analysis. For details on the method see Tettelin et al. 2002. NP_687967.1 identified by match to PFAM protein family HMM PF00005 NP_687970.1 identified by match to PFAM protein family HMM PF00070 NP_687971.1 Converts (S)-lactate and NAD(+) to pyruvate and NADH NP_687972.1 negatively supercoils closed circular double-stranded DNA NP_687973.1 identified by match to TIGR protein family HMM TIGR01076 NP_687974.1 identified by match to PFAM protein family HMM PF00903 NP_687976.1 identified by match to PFAM protein family HMM PF00999 NP_687977.1 similar to OMNI:SP0537; identified by sequence similarity NP_687978.1 identified by match to PFAM protein family HMM PF01609 NP_687979.1 contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway NP_687980.1 identified by match to PFAM protein family HMM PF00392 NP_687981.1 TrmFO; Gid; glucose-inhibited division protein; similar to GidA; the gene from Bacillus subtilis encodes a tRNA-methyltransferase that utilizes folate as the carbon donor and bound flavin as reductant; modifies tRNA at position 54 (uridine) of the T-psi loop to form a C5-methyluridine NP_687982.1 identified by match to PFAM protein family HMM PF00583 NP_687983.1 identified by match to PFAM protein family HMM PF03180; The product of this gene was detected by Western blot analysis. For details on the method see Tettelin et al. 2002. NP_687985.1 identified by match to PFAM protein family HMM PF00005 NP_687986.1 similar to OMNI:NTL01LL1789; identified by sequence similarity NP_687987.1 identified by match to PFAM protein family HMM PF00072 NP_687988.1 identified by match to PFAM protein family HMM PF00512 NP_687989.1 site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; cell division protein FtsK may regulate the XerS NP_687990.1 identified by match to PFAM protein family HMM PF00496 NP_687992.1 similar to GP:11055964; identified by sequence similarity NP_687993.1 identified by match to PFAM protein family HMM PF00448 NP_687995.1 identified by match to PFAM protein family HMM PF00512 NP_687996.1 identified by match to PFAM protein family HMM PF00072 NP_687997.1 identified by match to PFAM protein family HMM PF01433 NP_687998.1 identified by match to PFAM protein family HMM PF01895 NP_687999.1 ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation NP_688000.1 ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation NP_688001.1 identified by match to PFAM protein family HMM PF00528 NP_688002.1 identified by match to PFAM protein family HMM PF00528 NP_688003.1 identified by match to PFAM protein family HMM PF01449 NP_688004.1 identified by match to PFAM protein family HMM PF01189 NP_688005.1 identified by match to PFAM protein family HMM PF00459 NP_688007.1 the anti-alpha factor Spx interacts with RNA polymerase alpha subunit C-terminal domain in a region that interacts with the sigma 70 subunit and may interfere with activation of promoters; in Bacillus subtilis this protein is a substrate for ClpXP protease; blocks transcription of the competence regulatory gene encoded by the srf operon; regulates a number of genes involved in thiol homeostasis including trxA and trxB; monomeric member of ArsC family of proteins; does not bind DNA; contains a disulfide bond between C10 and C13 which may sense disulfide stress NP_688008.1 catalyzes the formation of FMN from riboflavin and the formation of FAD from FMN; in Bacillus the ribC gene has both flavokinase and FAD synthetase activities NP_688009.1 catalyzes isomerization of specific uridines in RNA to pseudouridine; responsible for residues in T loops of many tRNAs NP_688010.1 identified by match to PFAM protein family HMM PF00583 NP_688013.1 identified by match to PFAM protein family HMM PF02517 NP_688014.1 identified by match to PFAM protein family HMM PF02687 NP_688015.1 identified by match to PFAM protein family HMM PF00005 NP_688016.1 catalyzes the ATP-dependent breakage of single-stranded DNA followed by passage and rejoining, maintains net negative superhelicity NP_688017.1 identified by match to PFAM protein family HMM PF02481 NP_688018.1 identified by match to PFAM protein family HMM PF01497 NP_688019.1 identified by match to PFAM protein family HMM PF00005 NP_688020.1 identified by match to PFAM protein family HMM PF01032 NP_688021.1 identified by match to PFAM protein family HMM PF01032 NP_688022.1 identified by match to PFAM protein family HMM PF00132 NP_688023.1 RNH2; RNase HII; binds manganese; endonuclease which specifically degrades the RNA of RNA-DNA hybrids NP_688024.1 essential GTPase; functions in ribosome assembly; binds a unique part of the 23S rRNA; interacts with ribosomal protein L25(Ctc) NP_688025.1 identified by Glimmer2; The product of this gene was detected by Western blot analysis. For details on the method see Tettelin et al. 2002. NP_688027.1 identified by match to PFAM protein family HMM PF00072 NP_688028.1 identified by match to PFAM protein family HMM PF02518 NP_688040.1 similar to OMNI:SA0643; identified by sequence similarity; The product of this gene was detected by Western blot analysis. For details on the method see Tettelin et al. 2002. NP_688041.1 similar to GB:L13925 PID:466482; identified by sequence similarity NP_688043.1 identified by match to PFAM protein family HMM PF01580 NP_688050.1 similar to GP:14588952; identified by sequence similarity NP_688052.1 four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate; CarB is responsible for the amidotransferase activity NP_688053.1 catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers NP_688054.1 catalyzes the transfer of the carbamoyl moiety from carbamoyl phosphate to L- aspartate in pyrimidine biosynthesis NP_688055.1 catalyzes the formation of N-carbamoyl-L-aspartate from (S)-dihydroorotate in pyrimidine biosynthesis NP_688056.1 involved in fifth step of pyrimidine biosynthesis; converts orotidine 5'-phosphate and diphosphate to orotate and 5-phospho-alpha-D-ribose 1-diphosphate NP_688057.1 OMP decarboxylase; OMPDCase; OMPdecase; type 1 subfamily; involved in last step of pyrimidine biosynthesis; converts orotidine 5'-phosphate to UMP and carbon dioxide; OMP decarboxylase; OMPDCase; OMPdecase NP_688058.1 similar to OMNI:NTL01CA2266; identified by sequence similarity NP_688059.1 identified by match to PFAM protein family HMM PF00005 NP_688060.1 catalyzes the formation of 4-aspartyl phosphate from aspartate 4-semialdehyde NP_688063.2 identified by match to PFAM protein family HMM PF00614 NP_688064.1 catalyzes the formation of 10-formyltetrahydrofolate from formate and tetrahydrofolate NP_688065.1 identified by match to PFAM protein family HMM PF02539 NP_688068.1 identified by match to PFAM protein family HMM PF01597 NP_688069.1 identified by match to PFAM protein family HMM PF00296 NP_688070.1 identified by match to PFAM protein family HMM PF00724 NP_688072.1 similar to GB:L77117 PID:1591587; identified by sequence similarity NP_688073.1 decarboxylates 4-phosphopantothenoylcysteine to form 4'-phosphopantotheine. NP_688074.1 similar to OMNI:NTL01SPL0962; identified by sequence similarity NP_688075.1 identified by match to PFAM protein family HMM PF00408 NP_688077.1 identified by match to PFAM protein family HMM PF00665 NP_688079.1 identified by match to PFAM protein family HMM PF00005 NP_688080.1 identified by match to PFAM protein family HMM PF00005 NP_688083.1 catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate NP_688084.1 identified by match to PFAM protein family HMM PF01300 NP_688085.1 identified by match to TIGR protein family HMM TIGR00536 NP_688086.1 recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2 NP_688087.1 catalyzes the formation of thymidine 5'-phosphate from thymidine NP_688088.1 4-OT; member of subfamily 5; forms a dimer; the function in the Escherichia coli cell is unknown NP_688090.1 identified by match to PFAM protein family HMM PF02424 NP_688093.1 identified by match to PFAM protein family HMM PF01226 NP_688094.1 identified by match to PFAM protein family HMM PF00860 NP_688095.1 Catalyzes the transfer of the phosphoribosyl moiety from 5-phospho--D-ribosyl-1-pyrophosphate (PRib-PP) to the 6-oxo-guanine and -xanthine NP_688096.1 identified by match to PFAM protein family HMM PF00478 NP_688099.1 identified by match to PFAM protein family HMM PF02705 NP_688100.1 identified by match to PFAM protein family HMM PF00106 NP_688101.1 in Salmonella this enzyme is required for ethanolamine catabolism; has higher affinity for CoA than Pta NP_688102.1 identified by match to PFAM protein family HMM PF00849 NP_688103.1 catalyzes the phosphorylation of NAD to NADP NP_688104.1 similar to OMNI:NTL01SPL0878; identified by sequence similarity NP_688106.1 catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP NP_688107.1 identified by match to PFAM protein family HMM PF00266 NP_688109.1 modulates transcription in response to the NADH/NAD(+) redox state NP_688110.1 Involved in DNA double-strand break repair and recombination. Promotes the annealing of complementary single-stranded DNA and by simulation of RAD51 recombinase NP_688111.1 identified by match to PFAM protein family HMM PF01594 NP_688112.1 required for arbutin uptake and metabolism NP_688114.1 identified by match to PFAM protein family HMM PF00702 NP_688115.1 identified by match to PFAM protein family HMM PF00165 NP_688116.1 identified by match to PFAM protein family HMM PF00654 NP_688117.1 identified by match to PFAM protein family HMM PF01547 NP_688118.1 identified by match to PFAM protein family HMM PF00528 NP_688119.1 identified by match to PFAM protein family HMM PF00528 NP_688120.1 identified by match to PFAM protein family HMM PF00005 NP_688121.1 catalyzes the reduction of UDP-N-acetylglucosamine enolpyruvate to form UDP-N-acetylmuramate in peptidoglycan biosynthesis NP_688122.1 identified by match to PFAM protein family HMM PF01288 NP_688123.1 identified by match to PFAM protein family HMM PF02152 NP_688124.1 identified by match to PFAM protein family HMM PF00809 NP_688125.1 involved in the first step of tetrahydrofolate biosynthesis; catalyzes the formation of formate and 2-amino-4-hydroxy-6-(erythro-1,2, 3-trihydroxypropyl)dihydropteridine triphosphate from GTP and water; forms a homopolymer NP_688126.1 identified by match to TIGR protein family HMM TIGR01499 NP_688127.1 identified by match to PFAM protein family HMM PF00892 NP_688128.1 catalyzes the formation of O-phospho-L-homoserine from L-homoserine in threonine biosynthesis from asparate NP_688129.1 catalyzes the formation of L-aspartate 4-semialdehyde from L-homoserine NP_688130.1 identified by match to PFAM protein family HMM PF01522 NP_688131.1 identified by match to PFAM protein family HMM PF02028 NP_688133.1 identified by match to PFAM protein family HMM PF00171 NP_688135.1 similar to OMNI:NTL01SPL0680; identified by sequence similarity; The product of this gene was detected by Western blot analysis. For details on the method see Tettelin et al. 2002. NP_688136.1 similar to OMNI:NTL01SA1825; identified by sequence similarity NP_688137.1 identified by match to PFAM protein family HMM PF01381 NP_688140.1 antioxidant activity; thioredoxin-dependent thiol peroxidase; forms homodimers in solution; shows substrate specificity to alkyl hydroperoxides; periplasmic protein NP_688143.1 identified by match to PFAM protein family HMM PF00392 NP_688144.1 similar to OMNI:EF0080; identified by sequence similarity NP_688146.1 similar to OMNI:EF0604; identified by sequence similarity NP_688151.1 identified by match to PFAM protein family HMM PF00580 NP_688153.1 identified by match to PFAM protein family HMM PF00860 NP_688154.1 identified by match to PFAM protein family HMM PF01235 NP_688155.1 identified by match to PFAM protein family HMM PF01545 NP_688158.1 similar to OMNI:NTL01SPL1018; identified by sequence similarity NP_688159.1 in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins NP_688161.1 catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids NP_688162.1 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling NP_688163.1 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling NP_688164.1 involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsX NP_688165.1 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine NP_688167.1 identified by match to PFAM protein family HMM PF02348 NP_688170.1 identified by match to PFAM protein family HMM PF01354 NP_688171.1 identified by match to PFAM protein family HMM PF01943 NP_688172.1 similar to GP:13549137; identified by sequence similarity NP_688173.1 identified by match to PFAM protein family HMM PF00535 NP_688174.1 identified by match to PFAM protein family HMM PF00535 NP_688175.1 identified by match to PFAM protein family HMM PF00535 NP_688176.1 similar to GP:13549133; identified by sequence similarity NP_688177.1 similar to GP:13549132; identified by sequence similarity NP_688178.1 similar to GP:5823214; identified by sequence similarity NP_688179.1 similar to GP:13549130; identified by sequence similarity NP_688180.1 identified by match to PFAM protein family HMM PF02397 NP_688181.1 identified by match to TIGR protein family HMM TIGR01007 NP_688182.1 identified by match to PFAM protein family HMM PF02706 NP_688183.1 identified by match to PFAM protein family HMM PF02811 NP_688184.1 identified by match to TIGR protein family HMM TIGR00350 NP_688185.1 identified by match to PFAM protein family HMM PF00126 NP_688187.1 catalyzes the reversible phosphorolysis of ribonucleosides and 2'- deoxyribonucleosides to the free base and (2'-deoxy)ribose-1- phosphate NP_688188.1 identified by match to PFAM protein family HMM PF00654 NP_688189.1 catalyzes the formation of a purine and ribose phosphate from a purine nucleoside; in E. coli this enzyme functions in xanthosine degradation NP_688191.1 catalyzes the transfer of phosphate between the C1 and C5 carbons of pentose NP_688192.1 Catalyzes D-ribose 5-phosphate --> D-ribulose 5-phosphate in the nonoxidative branch of the pentose phosphate pathway NP_688194.1 similar to GP:7453518; identified by sequence similarity NP_688195.1 identified by match to PFAM protein family HMM PF00753 NP_688196.1 identified by match to PFAM protein family HMM PF00005 NP_688199.1 similar to OMNI:SP0966; identified by sequence similarity NP_688200.1 identified by match to PFAM protein family HMM PF03306 NP_688201.1 catalyzes the formation of 2-acetolactate from pyruvate in stationary phase NP_688202.1 identified by match to PFAM protein family HMM PF00515 NP_688203.1 identified by match to PFAM protein family HMM PF01594 NP_688204.1 identified by match to PFAM protein family HMM PF00293 NP_688205.1 identified by match to PFAM protein family HMM PF00293 NP_688206.1 identified by match to PFAM protein family HMM PF02278 NP_688207.1 identified by match to PFAM protein family HMM PF01370 NP_688208.1 identified by match to PFAM protein family HMM PF00908 NP_688209.1 identified by match to PFAM protein family HMM PF00483 NP_688210.1 identified by match to PFAM protein family HMM PF01266 NP_688213.1 identified by match to TIGR protein family HMM TIGR01446 NP_688214.1 catalyzes a salvage reaction resulting in the formation of AMP which is metabolically less costly than a de novo synthesis NP_688217.1 identified by match to PFAM protein family HMM PF01368 NP_688218.1 identified by match to PFAM protein family HMM PF00106 NP_688219.1 member of metallo-beta-lactamase family; the purified enzyme from Escherichia coli forms dimeric zinc phosphodiesterase; in Bacillus subtilis this protein is a 3'-tRNA processing endoribonuclease and is essential while in Escherichia coli it is not; associates with two zinc ions NP_688221.1 identified by match to TIGR protein family HMM TIGR00231 NP_688222.1 IPP transferase; isopentenyltransferase; involved in tRNA modification; in Escherichia coli this enzyme catalyzes the addition of a delta2-isopentenyl group from dimethylallyl diphosphate to the N6-nitrogen of adenosine adjacent to the anticodon of tRNA species that read codons starting with uracil; further tRNA modifications may occur; mutations in miaA result in defects in translation efficiency and fidelity NP_688224.1 similar to OMNI:SA1184; identified by sequence similarity NP_688225.1 identified by match to PFAM protein family HMM PF00128 NP_688227.1 divalent metal ion-dependent extracellular dipeptidase; able to hydrolyze a broad range of dipeptides but no tri-, tetra-, or larger oligopeptides; differences in the amino acid specificity of the cleavage site varies between species; similar to succinyl-diaminopimelate desuccinylases NP_688228.1 identified by match to PFAM protein family HMM PF00881 NP_688229.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision NP_688231.1 identified by match to PFAM protein family HMM PF01554 NP_688234.1 similar to GB:AL009126; identified by sequence similarity; The product of this gene was detected by Western blot analysis. For details on the method see Tettelin et al. 2002. NP_688235.1 identified by match to PFAM protein family HMM PF01527 NP_688236.1 identified by match to PFAM protein family HMM PF00665 NP_688238.1 identified by match to TIGR protein family HMM TIGR01363; The product of this gene was detected by Western blot analysis. For details on the method see Tettelin et al. 2002. NP_688239.1 identified by match to PFAM protein family HMM PF01297 NP_688240.1 identified by match to PFAM protein family HMM PF00078 NP_688244.1 identified by match to PFAM protein family HMM PF01527 NP_688245.1 identified by match to PFAM protein family HMM PF01527 NP_688246.1 identified by match to PFAM protein family HMM PF00665 NP_688249.1 identified by match to PFAM protein family HMM PF00589 NP_688251.1 identified by match to PFAM protein family HMM PF01381 NP_688252.1 identified by match to PFAM protein family HMM PF03432 NP_688253.1 similar to OMNI:SP1055; identified by sequence similarity NP_688254.1 similar to OMNI:SP1054; identified by sequence similarity NP_688255.1 identified by match to PFAM protein family HMM PF01610; This gene is located in a transposable element that also encodes two genes for a mercuric resistance operon, and there are two copies of the transposable element in this strain. NP_688256.1 identified by match to PFAM protein family HMM PF00070 NP_688257.1 identified by match to PFAM protein family HMM PF00376 NP_688258.1 identified by match to PFAM protein family HMM PF00122 NP_688259.1 identified by match to PFAM protein family HMM PF01022 NP_688263.1 identified by match to PFAM protein family HMM PF00122 NP_688264.1 similar to GP:9965434; identified by sequence similarity NP_688268.1 identified by match to PFAM protein family HMM PF01381 NP_688270.1 identified by match to PFAM protein family HMM PF00817 NP_688279.1 similar to GP:2735477; identified by sequence similarity NP_688280.1 identified by match to PFAM protein family HMM PF00176 NP_688282.1 similar to OMNI:EF0591; identified by sequence similarity NP_688283.1 identified by match to TIGR protein family HMM TIGR01167; The product of this gene was detected by Western blot analysis. For details on the method see Tettelin et al. 2002. NP_688284.1 similar to PID:1039476; identified by sequence similarity NP_688285.1 similar to GP:12620628; identified by sequence similarity NP_688287.1 The product of this gene was detected by Western blot analysis. For details on the method see Tettelin et al. 2002. NP_688288.1 similar to GP:11559691; identified by sequence similarity NP_688291.1 identified by match to PFAM protein family HMM PF02517 NP_688295.1 identified by match to PFAM protein family HMM PF00145 NP_688299.1 present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulates GTPase activity of translation factors NP_688300.1 binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit NP_688301.1 identified by match to PFAM protein family HMM PF00004 NP_688303.1 converts homocysteine and S-adenosyl-methionine to methionine and S-adenosyl-homocysteine or S-methyl-methionine and homocysteine to two methionines NP_688304.1 identified by match to PFAM protein family HMM PF00324 NP_688308.1 identified by match to PFAM protein family HMM PF00440 NP_688309.1 binds guanine nucleotides; in Escherichia coli depletion results in defective cell division and filamentation; in Bacillus subtilis this gene is essential NP_688310.1 binds and unfolds substrates as part of the ClpXP protease NP_688312.1 identified by match to PFAM protein family HMM PF00186 NP_688313.1 ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived NP_688314.1 identified by match to PFAM protein family HMM PF01154 NP_688315.1 identified by match to PFAM protein family HMM PF00368 NP_688317.1 identified by match to PFAM protein family HMM PF03006 NP_688320.1 similar to OMNI:SP1775; identified by sequence similarity NP_688321.1 catalyzes the isomerization of isopentenyl pyrophosphate to dimethylallyl diphosphate NP_688322.1 identified by match to TIGR protein family HMM TIGR01220 NP_688323.1 identified by match to PFAM protein family HMM PF00288 NP_688324.1 identified by match to PFAM protein family HMM PF00288 NP_688325.1 identified by match to PFAM protein family HMM PF00512 NP_688326.1 identified by match to PFAM protein family HMM PF00072 NP_688327.1 similar to OMNI:NTL01SPL0666; identified by sequence similarity NP_688329.1 identified by match to PFAM protein family HMM PF00746 NP_688330.1 identified by match to PFAM protein family HMM PF01047 NP_688331.1 identified by match to PFAM protein family HMM PF00149 NP_688332.1 cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+) NP_688333.1 converts 2-oxoglutarate to glutamate; in Escherichia coli this enzyme plays a role in glutamate synthesis when the cell is under energy restriction; uses NADPH; forms a homohexamer NP_688334.1 identified by sequence similarity NP_688335.1 identified by match to PFAM protein family HMM PF00005 NP_688336.1 identified by match to PFAM protein family HMM PF00005 NP_688337.1 identified by match to PFAM protein family HMM PF00583 NP_688338.1 identified by match to PFAM protein family HMM PF00005 NP_688339.1 catalyzes the addition and repair of the 3'-terminal CCA sequence in tRNA; these proteins belong to the CCA-adding enzyme subfamily 2 which does not have phosphohydrolase activity NP_688340.1 identified by match to PFAM protein family HMM PF02645 NP_688341.1 similar to OMNI:NTL01SPL0660; identified by sequence similarity; The product of this gene was detected by Western blot analysis. For details on the method see Tettelin et al. 2002. NP_688344.1 identified by match to PFAM protein family HMM PF00359 NP_688345.1 identified by match to PFAM protein family HMM PF00294 NP_688346.1 identified by match to PFAM protein family HMM PF00455 NP_688347.1 identified by match to PFAM protein family HMM PF02388 NP_688348.1 identified by match to TIGR protein family HMM TIGR01168 NP_688349.1 ketopantoate reductase; catalyzes the NADPH reduction of ketopantoate to pantoate; functions in pantothenate (vitamin B5) biosynthesis NP_688350.1 similar to OMNI:NTL01SPL0650; identified by sequence similarity NP_688351.1 identified by match to PFAM protein family HMM PF00070 NP_688352.1 methylates guanosine-37 in various tRNAs; uses S-adenosyl-L-methionine to transfer methyl group to tRNA NP_688353.1 Essential for efficient processing of 16S rRNA NP_688354.1 similar to GB:U01312 PID:460083; identified by sequence similarity NP_688355.1 identified by match to PFAM protein family HMM PF00013 NP_688356.1 binds to lower part of 30S body where it stabilizes two domains; required for efficient assembly of 30S; in Escherichia coli this protein has nuclease activity NP_688357.1 identified by match to PFAM protein family HMM PF02687 NP_688358.1 identified by match to PFAM protein family HMM PF00005 NP_688360.1 identified by match to PFAM protein family HMM PF02787 NP_688361.1 catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers NP_688362.1 regulates pyrimidine biosynthesis by binding to the mRNA of the pyr genes, also has been shown to have uracil phosphoribosyltransferase activity NP_688363.1 identified by match to PFAM protein family HMM PF00849 NP_688364.1 lipoprotein signal peptidase; integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis NP_688365.1 identified by match to PFAM protein family HMM PF00126 NP_688366.1 involved in the peptidyltransferase reaction during translation NP_688368.1 identified by match to PFAM protein family HMM PF00829 NP_688370.1 Required for the synthesis of the thiazole moiety NP_688371.1 identified by match to PFAM protein family HMM PF00266 NP_688373.1 catalyzes the reduction of 2 glutathione to glutathione disulfide; maintains high levels of reduced glutathione in the cytosol; involved in redox regulation and oxidative defense NP_688375.1 catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis NP_688376.1 catalyzes the formation of 3-dehydroquinate from 3-deoxy-arabino-heptulonate 7-phosphate; functions in aromatic amino acid biosynthesis NP_688377.1 catalyzes the dehydration of 3-dehydroquinate to form 3-dehydroshikimate in aromatic amino acid biosynthesis NP_688379.1 identified by match to PFAM protein family HMM PF00884 NP_688380.1 binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit NP_688381.1 identified by match to PFAM protein family HMM PF01632 NP_688382.1 IF-3 has several functions that are required and promote translation initiation including; preventing association of 70S by binding to 30S; monitoring codon-anticodon interactions by promoting disassociation of fMet-tRNA(fMet) from initiation complexes formed on leaderless mRNAs or incorrectly bound noninitiatior tRNAs and complexes with noncanonical start sites; stimulates codon-anticodon interactions at P-site; involved in moving mRNA to the P-site; and in recycling subunits NP_688383.1 Catalyzes the formation of (d)CDP from ATP and (d)CMP NP_688387.1 catalyzes the release of the N-terminal amino acid from a tripeptide NP_688388.1 identified by match to PFAM protein family HMM PF01943 NP_688389.1 involved in cell wall formation; peptidoglycan synthesis; cytoplasmic enzyme; catalyzes the addition of lysine to UDP-N-acetylmuramoyl-L-alanyl-D-glutamate forming UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysine NP_688390.1 identified by match to PFAM protein family HMM PF00005 NP_688391.1 identified by match to PFAM protein family HMM PF01497 NP_688392.1 identified by match to PFAM protein family HMM PF01032 NP_688393.1 identified by match to PFAM protein family HMM PF01032 NP_688395.1 catalyzes the hydrolysis of pyrophosphate to phosphate NP_688396.1 identified by match to PFAM protein family HMM PF02143 NP_688397.1 identified by match to PFAM protein family HMM PF00571 NP_688400.1 identified by match to PFAM protein family HMM PF01569 NP_688401.1 similar to OMNI:NTL01SPL0281; identified by sequence similarity NP_688402.1 identified by match to TIGR protein family HMM TIGR01167; The product of this gene was detected by Western blot analysis. For details on the method see Tettelin et al. 2002. NP_688403.1 identified by match to TIGR protein family HMM TIGR01076; The product of this gene was detected by Western blot analysis. For details on the method see Tettelin et al. 2002. NP_688404.1 identified by match to TIGR protein family HMM TIGR01076 NP_688405.1 identified by match to TIGR protein family HMM TIGR01167; The product of this gene was detected by Western blot analysis. For details on the method see Tettelin et al. 2002. NP_688407.1 identified by match to PFAM protein family HMM PF00534 NP_688408.1 identified by match to PFAM protein family HMM PF00535 NP_688409.1 identified by match to PFAM protein family HMM PF01943 NP_688411.1 identified by match to PFAM protein family HMM PF00535 NP_688412.1 identified by match to PFAM protein family HMM PF00535 NP_688414.1 identified by match to PFAM protein family HMM PF01128 NP_688415.1 similar to OMNI:EF2168; identified by sequence similarity NP_688418.1 identified by match to PFAM protein family HMM PF00535 NP_688419.1 identified by match to PFAM protein family HMM PF00535 NP_688421.1 identified by match to TIGR protein family HMM TIGR01214 NP_688423.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; primary sigma factor of bacterium NP_688424.1 synthesizes RNA primers at the replication forks NP_688425.1 identified by match to PFAM protein family HMM PF01741 NP_688426.1 a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA NP_688428.1 identified by match to PFAM protein family HMM PF00497 NP_688429.1 identified by match to PFAM protein family HMM PF00909 NP_688431.1 identified by match to PFAM protein family HMM PF00581 NP_688435.1 identified by match to PFAM protein family HMM PF00343 NP_688436.1 amylomaltase; acts to release glucose from maltodextrins NP_688437.1 identified by match to PFAM protein family HMM PF00356 NP_688438.1 identified by match to PFAM protein family HMM PF01547 NP_688439.1 identified by match to PFAM protein family HMM PF00528 NP_688440.1 identified by match to PFAM protein family HMM PF00528 NP_688441.1 identified by match to PFAM protein family HMM PF00854 NP_688444.1 identified by match to PFAM protein family HMM PF00534 NP_688445.1 functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; in some organisms, especially gram positive pathogens, have paralogs that have been found to be nonessential but do function in secretion of a subset of exported proteins NP_688446.1 similar to OMNI:SP1760; identified by sequence similarity NP_688449.1 forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase NP_688450.1 similar to GP:13346801; identified by sequence similarity NP_688451.1 identified by match to PFAM protein family HMM PF00535 NP_688452.1 identified by match to PFAM protein family HMM PF01609 NP_688453.1 similar to OMNI:SP0537; identified by sequence similarity NP_688454.1 identified by match to PFAM protein family HMM PF01501 NP_688455.1 identified by match to PFAM protein family HMM PF01501 NP_688457.1 identified by match to PFAM protein family HMM PF00746 NP_688458.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion NP_688459.1 identified by match to PFAM protein family HMM PF02517 NP_688460.1 identified by match to PFAM protein family HMM PF00497 NP_688461.1 identified by match to PFAM protein family HMM PF00005 NP_688464.2 essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication NP_688466.1 identified by match to PFAM protein family HMM PF02073 NP_688467.1 identified by match to TIGR protein family HMM TIGR01167 NP_688468.1 identified by match to PFAM protein family HMM PF01425 NP_688469.1 identified by match to PFAM protein family HMM PF00849 NP_688470.1 identified by match to PFAM protein family HMM PF00248 NP_688471.1 identified by match to PFAM protein family HMM PF00881 NP_688472.1 identified by match to PFAM protein family HMM PF00903 NP_688473.1 identified by match to PFAM protein family HMM PF00535 NP_688474.1 identified by match to PFAM protein family HMM PF00324 NP_688475.1 binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation NP_688476.1 identified by match to PFAM protein family HMM PF00575 NP_688478.1 in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif NP_688479.1 identified by match to PFAM protein family HMM PF00083 NP_688481.1 identified by match to PFAM protein family HMM PF00005 NP_688482.1 catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; involved in coenzyme A biosynthesis NP_688483.1 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases NP_688484.1 identified by match to PFAM protein family HMM PF01381 NP_688489.1 identified by match to PFAM protein family HMM PF02517 NP_688493.1 Era; Escherichia coli Ras-like protein; Bex; Bacillus Era-complementing segment; essential protein in Escherichia coli that is involved in many cellular processes; GTPase; binds the cell membrane through apparent C-terminal domain; mutants are arrested during the cell cycle; Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome NP_688494.1 identified by match to PFAM protein family HMM PF01219 NP_688496.1 similar to SP:P39887; identified by sequence similarity NP_688499.1 identified by match to PFAM protein family HMM PF00293 NP_688501.1 identified by match to PFAM protein family HMM PF02562 NP_688502.1 in group A Streptococci this protein was found to cross react with anti myosin antibodies and may play a role in rheumatic fever NP_688504.1 this stereospecific enzymes reduces the S isomer of methionine sulfoxide while MsrB reduces the R form; provides protection against oxidative stress NP_688506.1 Rrf; Frr; ribosome-recycling factor; release factor 4; RF4; recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G; A GTPase-dependent process results in release of 50S from 70S; inhibited by release factor RF-1; essential for viability; structurally similar to tRNAs NP_688507.1 Catalyzes the phosphorylation of UMP to UDP NP_688508.1 identified by match to PFAM protein family HMM PF00005 NP_688509.1 identified by match to PFAM protein family HMM PF00005 NP_688510.1 identified by match to PFAM protein family HMM PF00528 NP_688511.1 identified by match to PFAM protein family HMM PF00528 NP_688512.1 identified by match to PFAM protein family HMM PF00496 NP_688513.1 in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA NP_688514.1 binds directly to 23S ribosomal RNA NP_688515.1 identified by match to PFAM protein family HMM PF00665 NP_688517.1 identified by match to PFAM protein family HMM PF01546 NP_688518.1 identified by match to PFAM protein family HMM PF00126 NP_688521.1 identified by match to PFAM protein family HMM PF00665 NP_688522.1 identified by match to PFAM protein family HMM PF00425 NP_688523.1 identified by match to PFAM protein family HMM PF01580 NP_688524.1 identified by match to PFAM protein family HMM PF00160 NP_688525.1 identified by match to PFAM protein family HMM PF00950 NP_688526.1 identified by match to PFAM protein family HMM PF00005 NP_688527.1 identified by match to PFAM protein family HMM PF01297 NP_688528.1 identified by match to PFAM protein family HMM PF01325 NP_688529.1 enables the cleavage of the glycosidic bond in both 5'-methylthioadenosine and S-adenosylhomocysteine NP_688531.1 identified by match to PFAM protein family HMM PF00293 NP_688532.1 forms a homotrimer; catalyzes the acetylation of glucosamine-1-phosphate and uridylation of N-acetylglucosamine-1-phosphate to produce UDP-GlcNAc; function in cell wall synthesis NP_688536.1 identified by match to PFAM protein family HMM PF01408 NP_688537.1 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis NP_688540.1 identified by match to PFAM protein family HMM PF00583 NP_688541.1 identified by match to PFAM protein family HMM PF00535 NP_688542.1 similar to OMNI:SP0537; identified by sequence similarity NP_688543.1 identified by match to PFAM protein family HMM PF01609 NP_688549.1 identified by match to TIGR protein family HMM TIGR00796 NP_688550.1 methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content NP_688551.1 with TehA confers resistance to tellurite NP_688552.1 similar to OMNI:NTL01SPL0310; identified by sequence similarity NP_688556.1 identified by match to PFAM protein family HMM PF01260; In Gram negative bacteria, the apparent functional equivalent is known as exodeoxyribonuclease III (xth). NP_688558.1 identified by match to PFAM protein family HMM PF01035 NP_688559.1 identified by match to PFAM protein family HMM PF01842 NP_688560.1 identified by match to PFAM protein family HMM PF00583 NP_688561.1 similar to SP:P46719; identified by sequence similarity NP_688564.1 identified by match to PFAM protein family HMM PF00590 NP_688565.1 in Bacillus subtilis this protein is involved in the negative regulation of DNA replication initiation; interacts with DnaN and DnaA NP_688566.1 catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the delta' subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA. NP_688567.1 catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to thymidine monophosphate (dTMP) to form thymidine diphosphate (dTDP) NP_688568.1 identified by match to PFAM protein family HMM PF00571 NP_688569.1 identified by match to PFAM protein family HMM PF00005 NP_688570.1 identified by match to PFAM protein family HMM PF00005 NP_688571.1 identified by match to PFAM protein family HMM PF02653 NP_688572.1 identified by match to PFAM protein family HMM PF02653 NP_688575.1 identified by match to PFAM protein family HMM PF01609 NP_688576.1 hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates NP_688577.1 Catalyzes the formation of uracil and 5-phospho-alpha-D-ribosy 1-diphosphate from UMP and diphosphate NP_688578.1 identified by match to PFAM protein family HMM PF00155 NP_688579.1 identified by match to PFAM protein family HMM PF00588 NP_688580.1 identified by match to PFAM protein family HMM PF00324 NP_688581.1 involved in potassium uptake; found to be peripherally associated with the inner membrane in Escherichia coli; contains an NAD-binding domain NP_688582.1 identified by match to PFAM protein family HMM PF02386 NP_688584.1 identified by match to PFAM protein family HMM PF00849 NP_688585.1 functions during chromosome segregation; may form a condensin-like structure with SMC and ScpA; forms a homodimer NP_688586.1 functions during chromosome segregation; may form a condensin-like structure with SMC and ScpB NP_688587.1 site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs NP_688588.1 identified by match to PFAM protein family HMM PF00571 NP_688590.1 HAM1-like protein; Rec-dependent growth; RgdB; yggV; it is suspected that this protein functions to remove misincorporated bases such as xanthine or hypoxanthine NP_688591.1 converts L-glutamate to D-glutamate, a component of peptidoglycan NP_688593.1 similar to OMNI:NTL01SPL1119; identified by sequence similarity NP_688594.1 identified by match to PFAM protein family HMM PF02829 NP_688595.1 identified by match to PFAM protein family HMM PF01027 NP_688597.1 identified by match to PFAM protein family HMM PF00588 NP_688598.1 catalyzes the hydrolysis of acylphosphate NP_688599.1 involved in biogenesis of membrane proteins; Firmicutes specific proteins are shorter than other bacterial counterparts and have a signal peptide and lipid attachment site NP_688600.1 identified by match to PFAM protein family HMM PF00528 NP_688601.1 identified by match to PFAM protein family HMM PF00497 NP_688602.1 catalyzes the hydrolysis of a monocarboxylic acid amid to form a monocarboxylate and ammonia NP_688603.1 necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus NP_688605.1 identified by match to PFAM protein family HMM PF00583 NP_688606.1 Catalyzes the formation of UDP-N-acetylmuramoyl-L-alanine from UDP-N-acetylmuramate and L-alanine in peptidoglycan synthesis NP_688609.1 identified by match to PFAM protein family HMM PF00176; The product of this gene was detected by Western blot analysis. For details on the method see Tettelin et al. 2002. NP_688610.1 identified by match to PFAM protein family HMM PF01609 NP_688611.1 EngA; essential Neisserial GTPase; synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains NP_688612.1 Primosomal protein that may act to load helicase DnaC during DNA replication NP_688615.1 identified by match to PFAM protein family HMM PF00512 NP_688616.1 identified by match to PFAM protein family HMM PF00072 NP_688618.1 metalloprotease NP_688619.1 similar to OMNI:SP1284; identified by sequence similarity NP_688620.1 glucose-inhibited division protein B; SAM-dependent methyltransferase; methylates the N7 position of guanosine in position 527 of 16S rRNA NP_688621.1 identified by match to PFAM protein family HMM PF02386 NP_688622.1 identified by match to PFAM protein family HMM PF02254 NP_688623.1 identified by match to PFAM protein family HMM PF02361 NP_688624.1 identified by match to PFAM protein family HMM PF00005 NP_688626.1 involved in the import of serine and threonine coupled with the import of sodium NP_688627.1 identified by match to TIGR protein family HMM TIGR00796 NP_688628.1 identified by match to PFAM protein family HMM PF00107 NP_688629.1 identified by match to PFAM protein family HMM PF00528 NP_688630.1 identified by match to PFAM protein family HMM PF00005 NP_688631.1 identified by match to PFAM protein family HMM PF01546 NP_688632.1 identified by match to PFAM protein family HMM PF03180; The product of this gene was detected by Western blot analysis. For details on the method see Tettelin et al. 2002. NP_688633.1 identified by match to PFAM protein family HMM PF00497 NP_688634.1 identified by match to PFAM protein family HMM PF00117 NP_688638.1 similar to DhaK; in Lactococcus lactis this protein froms a stable complex with DhaS and activates transcription of the dha operon in the presence of dihydroxyacetone NP_688641.1 with DhaL and DhaM forms dihydroxyacetone kinase, which is responsible for phosphorylating dihydroxyacetone; DhaK is the dihydroxyacetone binding subunit of the dihydroxyacetone kinase NP_688642.1 identified by match to PFAM protein family HMM PF02734 NP_688644.1 identified by match to PFAM protein family HMM PF00230 NP_688646.1 identified by match to PFAM protein family HMM PF00376 NP_688650.1 identified by match to PFAM protein family HMM PF02410 NP_688651.1 identified by match to PFAM protein family HMM PF00857 NP_688653.1 transfers an adenyl group from ATP to NaMN to form nicotinic acid adenine dinucleotide (NaAD) which is then converted to the ubiquitous compound NAD by NAD synthetase; essential enzyme in bacteria NP_688655.1 in Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis NP_688656.1 identified by match to PFAM protein family HMM PF00702 NP_688657.1 identified by match to PFAM protein family HMM PF00892 NP_688658.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA NP_688659.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA NP_688660.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; some Mycoplasma proteins contain an N-terminal fusion to an unknown domain NP_688661.1 catalyzes the formation of phosphoenolpyruvate from pyruvate NP_688662.1 similar to OMNI:NTL01BH1376; identified by sequence similarity; The product of this gene was detected by Western blot analysis. For details on the method see Tettelin et al. 2002. NP_688663.1 identified by match to PFAM protein family HMM PF00571; In pairwise matches, the initiation methionine is located 40 residues upstream from the current start site of this gene; although there is strong sequence similarity, this ORF lacks an initiation codon in that upstream region. NP_688664.1 converts (S)-3-hydroxybutanoyl-CoA to 3-acetoacetyl-CoA NP_688665.1 identified by match to PFAM protein family HMM PF00857 NP_688666.1 CodY; DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase (By similarity). It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor NP_688667.1 broad specificity; family IV; in Corynebacterium glutamicum this protein can use glutamate, 2-aminobutyrate, and aspartate as amino donors and pyruvate as the acceptor NP_688669.1 identified by match to PFAM protein family HMM PF00702 NP_688670.1 identified by match to PFAM protein family HMM PF00710 NP_688671.1 identified by match to PFAM protein family HMM PF01488 NP_688672.1 identified by match to PFAM protein family HMM PF00248 NP_688673.1 catalyzes branch migration in Holliday junction intermediates NP_688674.1 similar to GP:1399011; identified by sequence similarity NP_688675.1 converts L-alanine to D-alanine which is used in cell wall biosynthesis; binds one pyridoxal phosphate per monomer; forms a homodimer NP_688676.1 Catalyzes the formation of holo-ACP, which mediates the essential transfer of acyl fatty acid intermediates during the biosynthesis of fatty acids and lipids NP_688677.1 catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, phenylalanine sensitive NP_688678.1 functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond SecA1; SecA2 is not essential and seems to play a role in secretion of a subset of proteins NP_688679.1 identified by match to PFAM protein family HMM PF01238 NP_688680.1 identified by match to PFAM protein family HMM PF00480 NP_688681.1 identified by match to PFAM protein family HMM PF00358 NP_688682.1 identified by match to PFAM protein family HMM PF00251 NP_688683.1 identified by match to PFAM protein family HMM PF00356 NP_688684.1 Regulates rRNA biosynthesis by transcriptional antitermination NP_688686.1 Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA NP_688695.1 identified by match to PFAM protein family HMM PF00383 NP_688697.1 identified by match to PFAM protein family HMM PF00083 NP_688699.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate NP_688701.1 identified by match to PFAM protein family HMM PF01544 NP_688702.1 binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit NP_688703.1 binds to single stranded DNA and may facilitate the binding and interaction of other proteins to DNA NP_688704.1 binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21 NP_688705.1 identified by match to PFAM protein family HMM PF00730 NP_688706.1 identified by match to PFAM protein family HMM PF01381 NP_688707.1 identified by match to PFAM protein family HMM PF00085 NP_688708.1 identified by match to PFAM protein family HMM PF01569 NP_688709.1 identified by match to PFAM protein family HMM PF00488; Function of MutS2 is unknown. It should not be considered a DNA mismatch repair protein. It is likely a DNA mismatch binding protein of unknown cellular function. NP_688712.1 An endonuclease that specifically degrades the RNA strand of RNA-DNA hybrids NP_688713.1 identified by match to PFAM protein family HMM PF00461 NP_688714.1 identified by match to TIGR protein family HMM TIGR01448 NP_688716.1 involved in translesion DNA polymerization with beta clamp of polymerase III; belongs to Y family of polymerases; does not contain proofreading function NP_688717.1 identified by match to PFAM protein family HMM PF01228 NP_688718.1 similar to SP:Q46604; identified by sequence similarity NP_688722.1 identified by match to PFAM protein family HMM PF00230 NP_688723.1 identified by match to PFAM protein family HMM PF00582 NP_688724.1 identified by match to PFAM protein family HMM PF00083 NP_688726.1 catalyzes the removal of N-terminal dipeptides when proline is the penultimate residue NP_688728.1 identified by match to PFAM protein family HMM PF00348 NP_688729.1 identified by match to PFAM protein family HMM PF00005 NP_688730.1 identified by match to PFAM protein family HMM PF00005 NP_688731.1 identified by match to PFAM protein family HMM PF02322 NP_688732.1 identified by match to PFAM protein family HMM PF01654 NP_688733.1 identified by match to PFAM protein family HMM PF00070 NP_688734.1 catalyzes the formation of dimethylmenaquinone from 1,4-dihydroxy-2-naphthoate and octaprenyl diphosphate NP_688738.1 identified by match to PFAM protein family HMM PF02353 NP_688739.1 identified by match to PFAM protein family HMM PF00376 NP_688740.1 3'-5' exonuclease of DNA polymerase III NP_688744.1 located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group do not appear to have the zinc-binding motif NP_688747.1 in most organisms, only the N-terminal domain is present in a single polypeptide; in some archaea this domain is fused to a kinase domain; this gene is essential for growth in Escherichia coli and Bacillus subtilis; the secreted glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins; the Pyrococcus structure shows DNA-binding properties, iron-binding, ATP-binding, and AP endonuclease activity NP_688748.1 identified by match to PFAM protein family HMM PF00583 NP_688749.1 The product of this gene was detected by Western blot analysis. For details on the method see Tettelin et al. 2002. NP_688751.1 identified by match to PFAM protein family HMM PF00753 NP_688753.1 identified by match to PFAM protein family HMM PF00120 NP_688754.1 identified by match to PFAM protein family HMM PF00376 NP_688756.1 Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway NP_688757.1 similar to GP:1944618; identified by sequence similarity NP_688758.1 catalyzes the formation of 3-phospho-D-glyceroyl phosphate from D-glyceraldehyde 3-phosphate NP_688759.1 EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene NP_688760.1 binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit NP_688761.1 interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance NP_688762.1 identified by match to PFAM protein family HMM PF00156 NP_688763.1 identified by match to PFAM protein family HMM PF01966 NP_688766.1 catalyzes the interconversion of D-ribulose 5-phosphate to xylulose 5-phosphate NP_688767.1 EngC; RsgA; CpgA; circularly permuted GTPase; ribosome small subunit-dependent GTPase A; has the pattern G4-G1-G3 as opposed to other GTPases; interacts strongly with 30S ribosome which stimulates GTPase activity NP_688768.1 similar to GB:D28496 SP:P36999 PID:460699 GB:U00096 PID:1736466; identified by sequence similarity NP_688769.1 catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin NP_688771.1 identified by match to PFAM protein family HMM PF01751 NP_688772.1 identified by match to PFAM protein family HMM PF01026 NP_688776.1 identified by Glimmer2; The product of this gene was detected by Western blot analysis. For details on the method see Tettelin et al. 2002. NP_688777.1 similar to OMNI:SP2173; identified by sequence similarity NP_688778.1 D-alanyl carrier protein subunit; involved in the incorporation of D-alanine into membrane-associated D-alanyl-lipoteichoic acid; D-alanyl carrier protein is the acceptor of activated D-alanine which it donates to a membrane acceptor(D-alanyl transferase) for incorporation into membrane lipoteichoic acid NP_688779.1 similar to OMNI:SP2175; identified by sequence similarity NP_688780.1 transfers D-alanine to the D-alanyl carrier protein during the incorporation of D-alanine into lipoteichoic acid NP_688781.1 identified by match to PFAM protein family HMM PF00512 NP_688782.1 identified by match to PFAM protein family HMM PF00072 NP_688783.1 in Escherichia coli transcription of this gene is enhanced by polyamines NP_688784.1 similar to OMNI:NTL01BH3953; identified by sequence similarity NP_688785.1 identified by match to PFAM protein family HMM PF00665 NP_688786.1 identified by match to PFAM protein family HMM PF00528 NP_688787.1 identified by match to PFAM protein family HMM PF00005 NP_688789.1 similar to SP:Q9AEM9; identified by sequence similarity NP_688791.1 identified by match to PFAM protein family HMM PF00874 NP_688793.1 identified by match to PFAM protein family HMM PF00370 NP_688796.1 identified by match to PFAM protein family HMM PF00389 NP_688798.1 identified by match to PFAM protein family HMM PF00356 NP_688799.1 similar to novel fructose-6-phosphate aldolase from Escherichia coli; enzyme from Methanocaldococcus janaschii shows transaldolase activity NP_688800.1 catalyzes the formation of D-xylulose 5-phosphate from L-ribulose 5-phosphate in the L-arabinose and L-ascorbate degradation pathways NP_688801.1 L-xylulose 5-phosphate 3-epimerase activity not yet demonstrated; may be involved in the utilization of 2,3-diketo-L-gulonate NP_688802.1 catalyzes the formation of L-xylulose-5-phosphate from 3-keto-L-gulonate-6-phosphate in anaerobic L-ascorbate utilization NP_688803.1 identified by match to PFAM protein family HMM PF00359 NP_688804.1 similar to OMNI:SP2037; identified by sequence similarity NP_688805.1 membrane component; functions with enzymes IIB (sgaB; ulaB) and IIA (sgaA; ulaC) enzyme I and HPr for anaerobic utilization and uptake of L-ascorbate; sgaTBA are regulated by yifQ as well as Crp and Fnr NP_688808.1 catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis NP_688809.1 identified by sequence similarity NP_688811.1 Synthesizes glutathione from L-glutamate and L-cysteine via gamma-L-glutamyl-L-cysteine NP_688812.1 similar to OMNI:NTL01SPL0121; identified by sequence similarity; The product of this gene was detected by Western blot analysis. For details on the method see Tettelin et al. 2002. NP_688813.1 similar to OMNI:NTL01SPL0120; identified by sequence similarity; The product of this gene was detected by Western blot analysis. For details on the method see Tettelin et al. 2002. NP_688814.1 becomes active under oxidative stress; four conserved cysteines bind a zinc atom when they are in the reduced state and the enzyme is inactive; oxidative stress results in oxidized cysteines, release of zinc, and binding of Hsp33 to aggregation-prone proteins; forms dimers and higher order oligomers NP_688815.1 identified by match to PFAM protein family HMM PF01207 NP_688816.1 identified by match to PFAM protein family HMM PF01712 NP_688817.1 identified by match to PFAM protein family HMM PF00583 NP_688818.1 identified by match to PFAM protein family HMM PF00004 NP_688819.1 similar to GB:D26185 SP:P37568 PID:467471 GB:AL009126; identified by sequence similarity NP_688821.1 EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu NP_688822.1 one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit NP_688823.1 identified by match to PFAM protein family HMM PF00578 NP_688824.1 identified by match to PFAM protein family HMM PF00070 NP_688827.1 identified by match to PFAM protein family HMM PF01832 NP_688828.1 similar to GP:13655626; identified by sequence similarity NP_688831.1 similar to PID:1514671; identified by sequence similarity NP_688832.1 similar to GP:10732859; identified by sequence similarity; PblB is a platelet adhesin. This version contains a 200aa insert that shows similarity (32% identity, 44% similarity over 95 residues) to SP|Q9TL08 a chloroplast enzyme which converts protoporphyrin IX (a hemoglobin precursor) into cholorophyll. NP_688841.1 similar to GB:AE001825; identified by sequence similarity NP_688843.1 similar to OMNI:CC2786; identified by sequence similarity NP_688845.1 identified by match to PFAM protein family HMM PF03354 NP_688847.1 identified by match to PFAM protein family HMM PF01844 NP_688849.1 identified by match to PFAM protein family HMM PF00589 NP_688851.1 identified by match to PFAM protein family HMM PF01381 NP_688853.1 identified by match to PFAM protein family HMM PF00436 NP_688859.1 identified by match to PFAM protein family HMM PF00145; Possibly an isoschizomer of Spn5252IP. NP_688862.1 identified by match to PFAM protein family HMM PF00772; In low GC Gram-postive bacteria this is known as dnaC. In other prokaryotes, functional equivalent known as dnaB. NP_688865.1 identified by match to PFAM protein family HMM PF01844 NP_688866.1 identified by match to PFAM protein family HMM PF02498 NP_688867.1 similar to GP:3676450; identified by sequence similarity NP_688874.1 identified by match to PFAM protein family HMM PF00589 NP_688876.1 identified by match to PFAM protein family HMM PF00999 NP_688878.1 identified by match to PFAM protein family HMM PF02016 NP_688879.1 identified by match to PFAM protein family HMM PF01431 NP_688880.1 identified by match to PFAM protein family HMM PF01408 NP_688883.1 identified by match to PFAM protein family HMM PF00027 NP_688884.1 cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+) NP_688885.1 identified by match to PFAM protein family HMM PF00532 NP_688890.1 similar to GP:5869507; identified by sequence similarity NP_688893.1 Involved in the nonphosphorylative, ketogenic oxidation of glucose and oxidizes gluconate to 5-ketogluconate NP_688895.1 identified by match to PFAM protein family HMM PF00294 NP_688896.1 catalyzes the formation of pyruvate and glyoxylate from 4-hydroxy-2-oxoglutarate; or pyruvate and D-glyceraldehyde 3-phosphate from 2-dehydro-3-deoxy-D-glyconate 6-phosphate NP_688898.1 identified by match to PFAM protein family HMM PF00881 NP_688899.1 identified by match to PFAM protein family HMM PF01047 NP_688900.1 catalyzes DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time; required for leading strand synthesis; PolC exhibits 3' to 5' exonuclease activity NP_688901.1 identified by match to PFAM protein family HMM PF01832 NP_688902.1 catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro) NP_688903.1 identified by match to TIGR protein family HMM TIGR00054 NP_688904.1 identified by match to PFAM protein family HMM PF01148 NP_688905.1 catalyzes the formation of undecaprenyl pyrophosphate from isopentenyl pyrophosphate NP_688906.1 member of preprotein translocase; forms a heterotrimer with SecD and SecF; links the SecD/SecF/YajC/YidC complex with the SecY/SecE/SecG complex NP_688907.1 The product of this gene was detected by Western blot analysis. For details on the method see Tettelin et al. 2002. NP_688908.1 identified by match to PFAM protein family HMM PF00390 NP_688909.1 identified by match to PFAM protein family HMM PF03390 NP_688910.1 similar to OMNI:NTL01SPL0863; identified by sequence similarity NP_688911.1 identified by match to PFAM protein family HMM PF00072 NP_688912.1 identified by match to PFAM protein family HMM PF01370 NP_688913.1 identified by match to PFAM protein family HMM PF00128 NP_688914.1 identified by match to PFAM protein family HMM PF00005 NP_688915.1 identified by match to TIGR protein family HMM TIGR01199 NP_688916.1 identified by match to PFAM protein family HMM PF02693 NP_688917.1 catalyzes the reversible reaction of dihydroxyacetone phosphate with glyceraldehyde 3-phosphate to produce tagatose 1,6-bisphosphate; in Streptococcus pyogenes there are two paralogs of tagatose-bisphosphate aldolase, encoded by lacD1 and lacD2; expression of lacD1 is highly regulated by environmental conditions while lacD2 specializes in an efficient utilization of carbohydrate sources NP_688918.1 catalyzes the formation of tagatose 1,6-bisphosphate from tagatose 6-phosphate and ATP NP_688919.1 catalyzes the interconversion of galactose 6-phosphate to tagatose 6-phosphate NP_688920.1 catalyzes the interconversion of galactose 6-phosphate to tagatose 6-phosphate; tagatose pathway for galactose utilization NP_688921.1 identified by match to PFAM protein family HMM PF02012 NP_688923.1 similar to OMNI:NTL01SPL1345; identified by sequence similarity NP_688925.1 identified by match to PFAM protein family HMM PF00455 NP_688926.1 identified by match to PFAM protein family HMM PF01297; The product of this gene was detected by Western blot analysis. For details on the method see Tettelin et al. 2002. NP_688927.1 hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr); possible defense mechanism against a harmful effect of D-tyrosine NP_688928.1 identified by match to PFAM protein family HMM PF01842 NP_688929.1 in Escherichia coli this is a periplasmic enzyme while in gram positive organisms it may be anchored at the cell surface; functions during ribonucleic acid degradation; 2',3'-cyclic nucleotides are first converted to 3'-nucleotide and then cleaved to yield a ribonucleotide and a phosphate NP_688930.1 has a stimulatory effect on the ribonucleotide reductase activity of NrdH with NrdEF NP_688933.1 identified by match to PFAM protein family HMM PF01547 NP_688934.1 identified by match to PFAM protein family HMM PF00072 NP_688940.1 similar to GP:7960293; identified by sequence similarity NP_688943.1 identified by match to PFAM protein family HMM PF00005 NP_688944.1 identified by match to PFAM protein family HMM PF00072 NP_688946.1 identified by match to PFAM protein family HMM PF00358 NP_688947.1 identified by match to PFAM protein family HMM PF00512 NP_688948.1 identified by match to PFAM protein family HMM PF00072 NP_688949.1 identified by match to PFAM protein family HMM PF01895 NP_688950.1 ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation NP_688951.1 identified by match to PFAM protein family HMM PF00528 NP_688952.1 identified by match to PFAM protein family HMM PF00528 NP_688955.1 in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA; cells lacking this function can grow, but are outcompeted by wild-type; SAM-dependent m(3)U1498 methyltransferase NP_688956.1 methylates ribosomal protein L11 at multiple amino acid positions; mutations of these genes in Escherichia coli or Thermus thermophilus has no apparent phenotype NP_688959.1 identified by match to PFAM protein family HMM PF00376 NP_688960.1 identified by match to PFAM protein family HMM PF00583 NP_688961.1 identified by match to PFAM protein family HMM PF00293 NP_688964.1 identified by match to PFAM protein family HMM PF00583 NP_688965.1 identified by match to PFAM protein family HMM PF00004 NP_688967.1 identified by match to PFAM protein family HMM PF00005 NP_688969.1 identified by match to PFAM protein family HMM PF01381 NP_688973.1 identified by match to PFAM protein family HMM PF00589 NP_688978.1 identified by match to PFAM protein family HMM PF01381 NP_688979.1 similar to PID:928833; identified by sequence similarity; The product of this gene was detected by Western blot analysis. For details on the method see Tettelin et al. 2002. NP_688980.1 identified by match to PFAM protein family HMM PF00589 NP_688987.1 similar to GP:6782407; identified by sequence similarity NP_688988.1 This gene is interrupted by an IS1381 element. NP_688989.1 identified by match to PFAM protein family HMM PF01609 NP_688990.2 similar to OMNI:SP0537; identified by sequence similarity NP_689001.1 identified by match to PFAM protein family HMM PF01381 NP_689003.1 identified by match to PFAM protein family HMM PF01381 NP_689004.1 identified by match to PFAM protein family HMM PF01580 NP_689007.1 identified by match to PFAM protein family HMM PF00746 NP_689008.1 identified by match to PFAM protein family HMM PF01610; This gene is located in a transposable element that also encodes two genes for a mercuric resistance operon, and there are two copies of the transposable element in this strain. NP_689009.1 identified by match to PFAM protein family HMM PF00070 NP_689010.1 identified by match to PFAM protein family HMM PF00376 NP_689011.1 identified by match to PFAM protein family HMM PF01566 NP_689012.1 similar to OMNI:NTL01SA2412; identified by sequence similarity NP_689013.1 identified by match to PFAM protein family HMM PF00005 NP_689015.1 similar to SP:P12055 GB:X06627 PID:46644; identified by sequence similarity NP_689019.1 identified by match to PFAM protein family HMM PF00583 NP_689020.1 similar to OMNI:NTL01BH0292; identified by sequence similarity NP_689021.1 identified by match to PFAM protein family HMM PF00005 NP_689023.1 identified by match to PFAM protein family HMM PF01381 NP_689024.1 identified by match to PFAM protein family HMM PF01569 NP_689027.1 identified by match to PFAM protein family HMM PF02517 NP_689028.1 identified by match to PFAM protein family HMM PF00581 NP_689029.1 similar to SP:P09879; identified by sequence similarity NP_689032.1 identified by match to PFAM protein family HMM PF00465 NP_689034.1 catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine; expressed in B. subtilis under methionine starvation conditions NP_689035.1 catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine to form methionine NP_689039.1 identified by match to PFAM protein family HMM PF00082 NP_689040.1 identified by match to PFAM protein family HMM PF00072 NP_689041.1 identified by match to PFAM protein family HMM PF00512 NP_689042.1 similar to OMNI:EF0852; identified by sequence similarity NP_689043.1 leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase NP_689044.1 identified by match to PFAM protein family HMM PF00083 NP_689045.1 identified by match to PFAM protein family HMM PF01734; The product of this gene was detected by Western blot analysis. For details on the method see Tettelin et al. 2002. NP_689046.1 identified by match to PFAM protein family HMM PF01501 NP_689047.1 identified by match to PFAM protein family HMM PF01501 NP_689048.1 Modulates Rho-dependent transcription termination NP_689049.1 identified by match to PFAM protein family HMM PF00746 NP_689050.1 forms a complex with SecY and SecG; SecYEG forms a protein-conducting channel to which secA binds and translocates targeted polypeptides across the cytoplasmic membrane, a process driven by ATP and a proton-motive force NP_689051.1 in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group have the CXXC motif NP_689052.1 identified by match to PFAM protein family HMM PF00905 NP_689053.1 identified by match to PFAM protein family HMM PF00849 NP_689055.1 catalyzes the transfer of phosphate between the C1 and C5 carbons of pentose NP_689056.1 catalyzes the formation of D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-D-ribose-5-phosphate NP_689057.1 identified by match to PFAM protein family HMM PF01773 NP_689058.1 identified by match to PFAM protein family HMM PF01048 NP_689059.1 identified by match to PFAM protein family HMM PF00392 NP_689060.1 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth NP_689061.1 10 kDa chaperonin; Cpn10; GroES; forms homoheptameric ring; binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it; folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES; release of the folded substrate is dependent on ATP-binding and hydrolysis in the trans ring NP_689062.1 identified by match to PFAM protein family HMM PF00005 NP_689063.1 identified by match to PFAM protein family HMM PF02653 NP_689064.1 similar to OMNI:SP1069; identified by sequence similarity; The product of this gene was detected by Western blot analysis. For details on the method see Tettelin et al. 2002. NP_689065.1 identified by match to PFAM protein family HMM PF00702 NP_689066.1 identified by match to PFAM protein family HMM PF00903 NP_689068.1 identified by match to PFAM protein family HMM PF02143 NP_689069.1 identified by match to PFAM protein family HMM PF00583 NP_689070.1 identified by match to PFAM protein family HMM PF01408 NP_689072.1 Catalyzes the reduction of nucleoside 5'-triphosphates to 2'-deoxynucleoside 5'-triphosphates NP_689073.1 similar to OMNI:NTL01SPL1648; identified by sequence similarity NP_689076.1 similar to RuvC resolvase with substantial differences; NMR structural information suggests this protein is monomeric; unknown cellular function NP_689078.1 the anti-alpha factor Spx interacts with RNA polymerase alpha subunit C-terminal domain in a region that interacts with the sigma 70 subunit and may interfere with activation of promoters; in Bacillus subtilis this protein is a substrate for ClpXP protease; blocks transcription of the competence regulatory gene encoded by the srf operon; regulates a number of genes involved in thiol homeostasis including trxA and trxB; monomeric member of ArsC family of proteins; does not bind DNA; contains a disulfide bond between C10 and C13 which may sense disulfide stress NP_689079.1 catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs NP_689080.1 identified by match to PFAM protein family HMM PF03352 NP_689081.1 plays an essential role in ATP-dependent branch migration of the Holliday junction NP_689083.1 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. Promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex NP_689085.1 identified by match to PFAM protein family HMM PF00313 NP_689086.1 This protein performs the mismatch recognition step during the DNA repair process NP_689087.1 identified by match to PFAM protein family HMM PF01316 NP_689088.1 catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase NP_689092.1 catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes NP_689093.1 catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG NP_689094.1 some L32 proteins have zinc finger motifs consisting of CXXC while others do not NP_689095.1 in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif NP_689097.1 identified by match to PFAM protein family HMM PF00589 NP_689103.1 identified by match to PFAM protein family HMM PF01381; The product of this gene was detected by Western blot analysis. For details on the method see Tettelin et al. 2002. NP_689104.1 similar to GP:15161770; identified by sequence similarity NP_689106.1 identified by Glimmer2; The product of this gene was detected by Western blot analysis. For details on the method see Tettelin et al. 2002. NP_689107.1 identified by match to PFAM protein family HMM PF00072 NP_689108.1 identified by match to PFAM protein family HMM PF00512 NP_689110.1 catalyzes the reversible synthesis of carbamate and ATP from carbamoyl phosphate and ADP NP_689111.1 catalyzes the formation of L-citrulline from carbamoyl phosphate and L-ornithine in arginine biosynthesis and degradation NP_689112.1 identified by match to PFAM protein family HMM PF02518 NP_689113.1 identified by match to PFAM protein family HMM PF00072 NP_689114.1 identified by match to PFAM protein family HMM PF00005 NP_689115.1 identified by match to PFAM protein family HMM PF00528 NP_689119.1 similar to OMNI:NTL01SPL1699; identified by sequence similarity NP_689122.1 primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination NP_689124.1 unwinds double stranded DNA NP_689125.1 in Escherichia coli this protein is wrapped around the base of the L1 stalk NP_689126.1 identified by match to PFAM protein family HMM PF01368; The product of this gene was detected by Western blot analysis. For details on the method see Tettelin et al. 2002. NP_689127.1 GidA; glucose-inhibited cell division protein A; involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U) of the wobble uridine base in some tRNAs NP_689128.1 identified by match to PFAM protein family HMM PF01914 NP_689129.1 catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs NP_689130.1 identified by match to PFAM protein family HMM PF01842 NP_689131.1 identified by match to PFAM protein family HMM PF03313 NP_689132.1 similar to OMNI:NTL01SPL1712; identified by sequence similarity; The product of this gene was detected by Western blot analysis. For details on the method see Tettelin et al. 2002. NP_689133.1 identified by match to PFAM protein family HMM PF01476 NP_689134.1 identified by match to PFAM protein family HMM PF02361 NP_689135.1 with CbiNQ forms the ABC transporter for cobalt import; Streptococcus has two adjacent copies of this gene NP_689136.1 with CbiNQ forms the ABC transporter for cobalt import; Streptococcus has two adjacent copies of this gene NP_689137.1 identified by match to PFAM protein family HMM PF01066 NP_689138.1 identified by match to PFAM protein family HMM PF00675 NP_689141.1 Required for DNA replication; binds preferentially to single-stranded, linear DNA NP_689142.1 identified by match to PFAM protein family HMM PF00892 NP_689143.1 identified by match to PFAM protein family HMM PF01381 NP_689144.1 catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate NP_689145.1 identified by match to PFAM protein family HMM PF02863 NP_689146.1 identified by match to PFAM protein family HMM PF00027 NP_689148.1 catalyzes the degradation of arginine to citruline and ammonia NP_689149.1 identified by match to PFAM protein family HMM PF00583 NP_689150.1 catalyzes the formation of ornithine and carbamylphosphate from citrulline in the arginine catabolic pathway NP_689151.1 identified by match to PFAM protein family HMM PF00324 NP_689152.1 catalyzes the reversible synthesis of carbamate and ATP from carbamoyl phosphate and ADP NP_689153.1 catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA NP_689156.1 identified by match to PFAM protein family HMM PF00005 NP_689157.1 similar to OMNI:NTL01SPL1730; identified by sequence similarity NP_689158.1 SPOUT methyltransferase family protein; crystal structure shows homodimer; in Escherichia coli this protein methylates pseudouridine at position 1915 of the 23S ribosomal RNA NP_689159.1 identified by match to PFAM protein family HMM PF00089 NP_689160.1 identified by match to PFAM protein family HMM PF02195