-- dump date 20140620_081032 -- class Genbank::Feature -- table feature -- table main -- field 1 id -- field 2 type -- field 3 name -- field 4 contig -- field 5 start_pos -- field 6 end_pos -- field 7 strand -- field 8 description -- field 9 chrom_position -- field 10 organism -- field 11 GeneID -- header -- id type name contig start_pos end_pos strand description chrom_position organism GeneID 208435000001 SEQ_END SEQ_END NC_004116.1 2160267 2160267 DR NC_004116.1; contig end 2160267..2160267 Streptococcus agalactiae 2603V/R NP_687037.1 CDS dnaA NC_004116.1 102 1463 D binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication; can also affect transcription of multiple genes including itself.; chromosome replication initiator DnaA 102..1463 Streptococcus agalactiae 2603V/R 1012723 NP_687038.1 CDS dnaN NC_004116.1 1618 2754 D binds the polymerase to DNA and acts as a sliding clamp; DNA polymerase III subunit beta 1618..2754 Streptococcus agalactiae 2603V/R 1012719 NP_687039.1 CDS SAG0003 NC_004116.1 2824 3705 D identified by match to PFAM protein family HMM PF00781; diacylglycerol kinase catalytic subunit 2824..3705 Streptococcus agalactiae 2603V/R 1012720 NP_687040.1 CDS SAG0004 NC_004116.1 3715 3912 D hypothetical protein 3715..3912 Streptococcus agalactiae 2603V/R 1012721 NP_687041.1 CDS SAG0005 NC_004116.1 4114 4317 D hypothetical protein 4114..4317 Streptococcus agalactiae 2603V/R 1012722 NP_687042.1 CDS ychF NC_004116.1 4477 5592 D translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1; GTP-dependent nucleic acid-binding protein EngD 4477..5592 Streptococcus agalactiae 2603V/R 1012724 NP_687043.1 CDS pth NC_004116.1 5676 6251 D Enables the recycling of peptidyl-tRNAs produced at termination of translation; peptidyl-tRNA hydrolase 5676..6251 Streptococcus agalactiae 2603V/R 1012725 NP_687044.1 CDS mfd NC_004116.1 6248 9745 D identified by match to PFAM protein family HMM PF00270; transcription-repair coupling factor 6248..9745 Streptococcus agalactiae 2603V/R 1012726 NP_687045.1 CDS SAG0009 NC_004116.1 9906 10001 D hypothetical protein 9906..10001 Streptococcus agalactiae 2603V/R 1012727 NP_687046.1 CDS SAG0010 NC_004116.1 10036 10308 D identified by match to PFAM protein family HMM PF01479; S4 domain-containing protein 10036..10308 Streptococcus agalactiae 2603V/R 1012728 NP_687047.1 CDS SAG0011 NC_004116.1 10295 10666 D similar to OMNI:NTL01SPL0011; identified by sequence similarity; hypothetical protein 10295..10666 Streptococcus agalactiae 2603V/R 1012729 NP_687048.1 CDS SAG0012 NC_004116.1 10669 10803 D hypothetical protein 10669..10803 Streptococcus agalactiae 2603V/R 1012730 NP_687049.1 CDS SAG0013 NC_004116.1 10803 12089 D The product of this gene was detected by Western blot analysis. For details on the method see Tettelin et al. 2002.; hypothetical protein 10803..12089 Streptococcus agalactiae 2603V/R 1012731 NP_687050.1 CDS SAG0014 NC_004116.1 12091 13365 D MesJ/Ycf62 family protein 12091..13365 Streptococcus agalactiae 2603V/R 1012732 NP_687051.1 CDS hpt NC_004116.1 13370 13912 D Catalyzes the salvage synthesis of inosine-5'-monophosphate (IMP) and guanosine-5'-monophosphate (GMP) from the purine bases hypoxanthine and guanine, respectively; hypoxanthine-guanine phosphoribosyltransferase 13370..13912 Streptococcus agalactiae 2603V/R 1012733 NP_687052.1 CDS ftsH NC_004116.1 13935 15911 D identified by match to PFAM protein family HMM PF00004; cell division protein FtsH 13935..15911 Streptococcus agalactiae 2603V/R 1012734 NP_687053.1 CDS pscB NC_004116.1 28902 30245 D similar to GP:12667037; identified by sequence similarity; PcsB protein 28902..30245 Streptococcus agalactiae 2603V/R 1012767 NP_687054.1 CDS prsA-1 NC_004116.1 30369 31337 D catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP; ribose-phosphate pyrophosphokinase 30369..31337 Streptococcus agalactiae 2603V/R 1012768 NP_687055.1 CDS SAG0019 NC_004116.1 31445 32620 D catalyzes the transamination of the aromatic amino acid forming a ketoacid; first step in aromatic amino acid degradation in lactococci; aromatic amino acid aminotransferase 31445..32620 Streptococcus agalactiae 2603V/R 1012769 NP_687056.1 CDS recO NC_004116.1 32610 33371 D involved in DNA repair and RecFOR pathway recombination; RecFOR proteins displace ssDNA-binding protein and facilitate the production of RecA-coated ssDNA; DNA repair protein RecO 32610..33371 Streptococcus agalactiae 2603V/R 1012770 NP_687057.1 CDS SAG0021 NC_004116.1 33461 34312 D identified by match to PFAM protein family HMM PF02517; protease 33461..34312 Streptococcus agalactiae 2603V/R 1012771 NP_687058.1 CDS plsX NC_004116.1 34390 35382 D involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsY; glycerol-3-phosphate acyltransferase PlsX 34390..35382 Streptococcus agalactiae 2603V/R 1012772 NP_687059.1 CDS acpP-1 NC_004116.1 35393 35632 D carries the fatty acid chain in fatty acid biosynthesis; acyl carrier protein 35393..35632 Streptococcus agalactiae 2603V/R 1012773 NP_687060.1 CDS purC NC_004116.1 35756 36460 D catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis; SAICAR synthase; phosphoribosylaminoimidazole-succinocarboxamide synthase 35756..36460 Streptococcus agalactiae 2603V/R 1012774 NP_687061.1 CDS SAG0025 NC_004116.1 36583 40308 D identified by match to PFAM protein family HMM PF02769; phosphoribosylformylglycinamidine synthase 36583..40308 Streptococcus agalactiae 2603V/R 1012775 NP_687062.1 CDS purF NC_004116.1 40720 42174 D Catalyzes first step of the de novo purine nucleotide biosynthetic pathway; amidophosphoribosyltransferase 40720..42174 Streptococcus agalactiae 2603V/R 1012776 NP_687063.1 CDS purM NC_004116.1 42202 43224 D catalyzes the formation of 1-(5-phosphoribosyl)-5-aminoimidazole from 2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in purine biosynthesis; phosphoribosylaminoimidazole synthetase 42202..43224 Streptococcus agalactiae 2603V/R 1012777 NP_687064.1 CDS purN NC_004116.1 43392 43940 D glycinamide ribonucleotide transformylase; GAR Tfase; catalyzes the synthesis of 5'-phosphoribosylformylglycinamide from 5'-phosphoribosylglycinamide and 10-formyltetrahydrofolate; PurN requires formyl folate for the reaction unlike PurT which uses formate; phosphoribosylglycinamide formyltransferase 43392..43940 Streptococcus agalactiae 2603V/R 1012778 NP_687065.1 CDS SAG0029 NC_004116.1 43963 44715 D identified by match to PFAM protein family HMM PF00583; acetyltransferase 43963..44715 Streptococcus agalactiae 2603V/R 1012779 NP_687066.1 CDS purH NC_004116.1 44735 46282 D involved in de novo purine biosynthesis; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 44735..46282 Streptococcus agalactiae 2603V/R 1012780 NP_687067.1 CDS SAG0031 NC_004116.1 46475 47374 D identified by match to PFAM protein family HMM PF01551; M24/M37 family peptidase 46475..47374 Streptococcus agalactiae 2603V/R 1012781 NP_687068.1 CDS SAG0032 NC_004116.1 47521 48825 D identified by match to PFAM protein family HMM PF01476; group B streptococcal surface immunogenic protein 47521..48825 Streptococcus agalactiae 2603V/R 1012782 NP_687069.1 CDS SAG0033 NC_004116.1 49072 49770 D Converts N-acetylmannosamine-6-phosphate to N-acetylglucosamine-6-phosphate; N-acetylmannosamine-6-phosphate 2-epimerase 49072..49770 Streptococcus agalactiae 2603V/R 1012783 NP_687070.1 CDS SAG0034 NC_004116.1 49817 51133 D identified by match to PFAM protein family HMM PF01547; sugar ABC transporter sugar-binding protein 49817..51133 Streptococcus agalactiae 2603V/R 1012784 NP_687071.1 CDS SAG0035 NC_004116.1 51221 52108 D identified by match to PFAM protein family HMM PF00528; sugar ABC transporter permease 51221..52108 Streptococcus agalactiae 2603V/R 1012785 NP_687072.1 CDS SAG0036 NC_004116.1 52118 52948 D identified by match to PFAM protein family HMM PF00528; sugar ABC transporter permease 52118..52948 Streptococcus agalactiae 2603V/R 1012786 NP_687073.1 CDS SAG0037 NC_004116.1 52961 53404 D hypothetical protein 52961..53404 Streptococcus agalactiae 2603V/R 1012787 NP_687074.1 CDS SAG0038 NC_004116.1 53424 54086 D hypothetical protein 53424..54086 Streptococcus agalactiae 2603V/R 1012788 NP_687075.1 CDS SAG0039 NC_004116.1 54083 55000 D identified by match to PFAM protein family HMM PF00701; N-acetylneuraminate lyase 54083..55000 Streptococcus agalactiae 2603V/R 1012789 NP_687076.1 CDS SAG0040 NC_004116.1 55017 55898 D identified by match to PFAM protein family HMM PF00480; The product of this gene was detected by Western blot analysis. For details on the method see Tettelin et al. 2002.; ROK family protein 55017..55898 Streptococcus agalactiae 2603V/R 1012790 NP_687077.1 CDS SAG0041 NC_004116.1 55906 56883 D acetyl xylan esterase 55906..56883 Streptococcus agalactiae 2603V/R 1012791 NP_687078.1 CDS SAG0042 NC_004116.1 56906 57709 R identified by match to PFAM protein family HMM PF01380; RpiR family transcriptional regulator complement(56906..57709) Streptococcus agalactiae 2603V/R 1012792 NP_687079.1 CDS purD NC_004116.1 57991 59256 D catalyzes the formation of N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-D-ribosylamine and glycine in purine biosynthesis; phosphoribosylamine--glycine ligase 57991..59256 Streptococcus agalactiae 2603V/R 1012793 NP_687080.1 CDS purE NC_004116.1 59537 60025 D Catalyzes a step in the de novo purine nucleotide biosynthetic pathway; phosphoribosylaminoimidazole carboxylase catalytic subunit 59537..60025 Streptococcus agalactiae 2603V/R 1012794 NP_687081.1 CDS purK NC_004116.1 60012 61103 D With PurE catalyzes the conversion of aminoimidazole ribonucleotide to carboxyaminoimidazole ribonucleotide in the de novo purine nucleotide biosynthetic pathway; phosphoribosylaminoimidazole carboxylase ATPase subunit 60012..61103 Streptococcus agalactiae 2603V/R 1012795 NP_687082.1 CDS SAG0046 NC_004116.1 61157 62548 D hypothetical protein 61157..62548 Streptococcus agalactiae 2603V/R 1012796 NP_687083.1 CDS purB NC_004116.1 62573 63871 D Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide; adenylosuccinate lyase 62573..63871 Streptococcus agalactiae 2603V/R 1012797 NP_687084.1 CDS SAG0048 NC_004116.1 64023 64934 D identified by match to PFAM protein family HMM PF01381; Cro/CI family transcriptional regulator 64023..64934 Streptococcus agalactiae 2603V/R 1012798 NP_687085.1 CDS ruvB NC_004116.1 65231 66229 D promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration; Holliday junction DNA helicase RuvB 65231..66229 Streptococcus agalactiae 2603V/R 1012799 NP_687086.1 CDS SAG0050 NC_004116.1 66381 66818 D identified by match to PFAM protein family HMM PF01451; phosphotyrosine protein phosphatase, low molecular weight 66381..66818 Streptococcus agalactiae 2603V/R 1012800 NP_687087.1 CDS SAG0051 NC_004116.1 66825 67205 D identified by match to PFAM protein family HMM PF02493; MORN motif-containing protein 66825..67205 Streptococcus agalactiae 2603V/R 1012801 NP_687088.1 CDS SAG0052 NC_004116.1 67202 68980 D identified by match to PFAM protein family HMM PF01757; hypothetical protein 67202..68980 Streptococcus agalactiae 2603V/R 1012802 NP_687089.1 CDS adhE NC_004116.1 69250 71892 D identified by match to PFAM protein family HMM PF00171; bifunctional acetaldehyde-CoA/alcohol dehydrogenase 69250..71892 Streptococcus agalactiae 2603V/R 1012803 NP_687090.1 CDS adhP NC_004116.1 72071 73087 D similar to zinc-dependent eukaryotic ADH enzymes and distinct from fermentative ADHs; alcohol dehydrogenase 72071..73087 Streptococcus agalactiae 2603V/R 1012804 NP_687091.1 CDS thrC NC_004116.1 73207 74697 D catalyzes the formation of L-threonine from O-phospho-L-homoserine; threonine synthase 73207..74697 Streptococcus agalactiae 2603V/R 1012805 NP_687092.1 CDS SAG0056 NC_004116.1 74844 76082 D identified by match to PFAM protein family HMM PF01554; MATE efflux family protein 74844..76082 Streptococcus agalactiae 2603V/R 1012806 NP_687093.1 CDS rpsJ NC_004116.1 76288 76596 D NusE; involved in assembly of the 30S subunit; in the ribosome, this protein is involved in the binding of tRNA; in Escherichia coli this protein was also found to be involved in transcription antitermination; NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination; binding of NusB/S10 to boxA nucleates assembly of the antitermination complex; 30S ribosomal protein S10 76288..76596 Streptococcus agalactiae 2603V/R 1012807 NP_687094.1 CDS rplC NC_004116.1 76701 77327 D binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin; 50S ribosomal protein L3 76701..77327 Streptococcus agalactiae 2603V/R 1012808 NP_687095.1 CDS rplD NC_004116.1 77351 77974 D L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA; 50S ribosomal protein L4 77351..77974 Streptococcus agalactiae 2603V/R 1012809 NP_687096.1 CDS rplW NC_004116.1 77974 78270 D binds third domain of 23S rRNA and protein L29; part of exit tunnel; 50S ribosomal protein L23 77974..78270 Streptococcus agalactiae 2603V/R 1012810 NP_687097.1 CDS rplB NC_004116.1 78288 79121 D one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation; 50S ribosomal protein L2 78288..79121 Streptococcus agalactiae 2603V/R 1012811 NP_687098.1 CDS rpsS NC_004116.1 79220 79498 D protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA; 30S ribosomal protein S19 79220..79498 Streptococcus agalactiae 2603V/R 1012812 NP_687099.1 CDS rplV NC_004116.1 79514 79858 D binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center; 50S ribosomal protein L22 79514..79858 Streptococcus agalactiae 2603V/R 1012813 NP_687100.1 CDS rpsC NC_004116.1 79871 80524 D forms a complex with S10 and S14; binds the lower part of the 30S subunit head and the mRNA in the complete ribosome to position it for translation; 30S ribosomal protein S3 79871..80524 Streptococcus agalactiae 2603V/R 1012814 NP_687101.1 CDS rplP NC_004116.1 80528 80941 D located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e; 50S ribosomal protein L16 80528..80941 Streptococcus agalactiae 2603V/R 1012815 NP_687102.1 CDS rpmC NC_004116.1 80951 81157 D one of the stabilizing components for the large ribosomal subunit; 50S ribosomal protein L29 80951..81157 Streptococcus agalactiae 2603V/R 1012816 NP_687103.1 CDS rpsQ NC_004116.1 81183 81443 D primary binding protein; helps mediate assembly; involved in translation fidelity; 30S ribosomal protein S17 81183..81443 Streptococcus agalactiae 2603V/R 1012817 NP_687104.1 CDS rplN NC_004116.1 81468 81836 D binds to the 23S rRNA between the centers for peptidyl transferase and GTPase; 50S ribosomal protein L14 81468..81836 Streptococcus agalactiae 2603V/R 1012818 NP_687105.1 CDS rplX NC_004116.1 81916 82221 D assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel; 50S ribosomal protein L24 81916..82221 Streptococcus agalactiae 2603V/R 1012819 NP_687106.1 CDS rplE NC_004116.1 82245 82787 D part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13; 50S ribosomal protein L5 82245..82787 Streptococcus agalactiae 2603V/R 1012820 NP_687107.1 CDS rpsN NC_004116.1 82805 82990 D located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group appear to contain the zinc-binding motif; 30S ribosomal protein S14 82805..82990 Streptococcus agalactiae 2603V/R 1012821 NP_687108.1 CDS rpsH NC_004116.1 83145 83543 D binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; 30S ribosomal protein S8 83145..83543 Streptococcus agalactiae 2603V/R 1012822 NP_687109.1 CDS rplF NC_004116.1 83653 84189 D ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance; 50S ribosomal protein L6 83653..84189 Streptococcus agalactiae 2603V/R 1012823 NP_687110.1 CDS rplR NC_004116.1 84290 84646 D binds 5S rRNA along with protein L5 and L25; 50S ribosomal protein L18 84290..84646 Streptococcus agalactiae 2603V/R 1012824 NP_687111.1 CDS rpsE NC_004116.1 84665 85159 D located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance; 30S ribosomal protein S5 84665..85159 Streptococcus agalactiae 2603V/R 1012825 NP_687112.1 CDS rpmD NC_004116.1 85174 85353 D L30 binds domain II of the 23S rRNA and the 5S rRNA; similar to eukaryotic protein L7; 50S ribosomal protein L30 85174..85353 Streptococcus agalactiae 2603V/R 1012826 NP_687113.1 CDS rplO NC_004116.1 85478 85918 D late assembly protein; 50S ribosomal protein L15 85478..85918 Streptococcus agalactiae 2603V/R 1012827 NP_687114.1 CDS secY NC_004116.1 85939 87243 D forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase; preprotein translocase subunit SecY 85939..87243 Streptococcus agalactiae 2603V/R 1012828 NP_687115.1 CDS adk NC_004116.1 87338 87976 D essential enzyme that recycles AMP in active cells; converts ATP and AMP to two molecules of ADP; adenylate kinase 87338..87976 Streptococcus agalactiae 2603V/R 1012829 NP_687116.1 CDS infA NC_004116.1 88092 88310 D stimulates the activities of the other two initiation factors, IF-2 and IF-3; translation initiation factor IF-1 88092..88310 Streptococcus agalactiae 2603V/R 1012830 NP_687117.1 CDS rpmJ NC_004116.1 88336 88452 D smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group have the motif; 50S ribosomal protein L36 88336..88452 Streptococcus agalactiae 2603V/R 1012831 NP_687118.1 CDS rpsM NC_004116.1 88470 88835 D located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA; 30S ribosomal protein S13 88470..88835 Streptococcus agalactiae 2603V/R 1012832 NP_687119.2 CDS rpsK NC_004116.1 88853 89236 D located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3; 30S ribosomal protein S11 88853..89236 Streptococcus agalactiae 2603V/R 1012833 NP_687120.1 CDS rpoA NC_004116.1 89286 90224 D catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme; DNA-directed RNA polymerase subunit alpha 89286..90224 Streptococcus agalactiae 2603V/R 1012834 NP_687121.1 CDS rplQ NC_004116.1 90239 90625 D is a component of the macrolide binding site in the peptidyl transferase center; 50S ribosomal protein L17 90239..90625 Streptococcus agalactiae 2603V/R 1012835 NP_687122.1 CDS SAG0086 NC_004116.1 97819 98076 D lipoprotein 97819..98076 Streptococcus agalactiae 2603V/R 1012854 NP_687123.1 CDS SAG0087 NC_004116.1 98067 98246 D hypothetical protein 98067..98246 Streptococcus agalactiae 2603V/R 1012855 NP_687124.1 CDS SAG0088 NC_004116.1 98316 98486 D hypothetical protein 98316..98486 Streptococcus agalactiae 2603V/R 1012856 NP_687125.1 CDS SAG0089 NC_004116.1 99401 99952 D hypothetical protein 99401..99952 Streptococcus agalactiae 2603V/R 1012857 NP_687126.1 CDS SAG0090 NC_004116.1 100172 100591 D hypothetical protein 100172..100591 Streptococcus agalactiae 2603V/R 1012858 NP_687127.1 CDS SAG0091 NC_004116.1 100836 101270 D similar to OMNI:SP0014; identified by sequence similarity; ComX1 family transcriptional regulator 100836..101270 Streptococcus agalactiae 2603V/R 1012859 NP_687128.1 CDS SAG0092 NC_004116.1 101392 102084 D identified by match to PFAM protein family HMM PF00300; phosphoglycerate mutase family protein 101392..102084 Streptococcus agalactiae 2603V/R 1012860 NP_687129.1 CDS SAG0093 NC_004116.1 102081 102833 D identified by match to PFAM protein family HMM PF02557; D-alanyl-D-alanine carboxypeptidase 102081..102833 Streptococcus agalactiae 2603V/R 1012861 NP_687130.1 CDS SAG0094 NC_004116.1 102830 103405 D identified by match to PFAM protein family HMM PF01832; N-acetylmuramoyl-L-alanine amidase 102830..103405 Streptococcus agalactiae 2603V/R 1012862 NP_687131.1 CDS hrcA NC_004116.1 103548 104582 D Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons; heat-inducible transcription repressor 103548..104582 Streptococcus agalactiae 2603V/R 1012863 NP_687132.1 CDS grpE NC_004116.1 104585 105157 D with DnaK and DnaJ acts in response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins; may act as a thermosensor; heat shock protein GrpE 104585..105157 Streptococcus agalactiae 2603V/R 1012864 NP_687133.1 CDS dnaK NC_004116.1 105338 107167 D heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria; molecular chaperone DnaK 105338..107167 Streptococcus agalactiae 2603V/R 1012865 NP_687134.1 CDS dnaJ NC_004116.1 107456 108595 D chaperone Hsp40; co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion; molecular chaperone DnaJ 107456..108595 Streptococcus agalactiae 2603V/R 1012866 NP_687135.1 CDS SAG0099 NC_004116.1 108709 109956 D identified by match to PFAM protein family HMM PF00392; GntR family transcriptional regulator 108709..109956 Streptococcus agalactiae 2603V/R 1012867 NP_687136.1 CDS truA NC_004116.1 110027 110803 D mediates pseudouridylation (positions 38, 39, 40) at the tRNA anticodon region which contributes to the structural stability; tRNA pseudouridine synthase A 110027..110803 Streptococcus agalactiae 2603V/R 1012868 NP_687137.1 CDS SAG0101 NC_004116.1 110766 111524 D catalyzes the formation of 4-amino-2-methyl-5-diphosphomethylpyrimidine; phosphomethylpyrimidine kinase 110766..111524 Streptococcus agalactiae 2603V/R 1012869 NP_687138.1 CDS SAG0102 NC_004116.1 111534 111998 D hypothetical protein 111534..111998 Streptococcus agalactiae 2603V/R 1012870 NP_687139.1 CDS SAG0103 NC_004116.1 111995 112564 D hypothetical protein 111995..112564 Streptococcus agalactiae 2603V/R 1012871 NP_687140.1 CDS SAG0104 NC_004116.1 112601 113443 R hypothetical protein complement(112601..113443) Streptococcus agalactiae 2603V/R 1012872 NP_687141.1 CDS tig NC_004116.1 113600 114883 D Tig; RopA; peptidyl-prolyl cis/trans isomerase; promotes folding of newly synthesized proteins; binds ribosomal 50S subunit; forms a homodimer; trigger factor 113600..114883 Streptococcus agalactiae 2603V/R 1012873 NP_687142.1 CDS SAG0106 NC_004116.1 115072 115647 D participates in both the initiation and recycling phases of transcription; in the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling; DNA-directed RNA polymerase subunit delta 115072..115647 Streptococcus agalactiae 2603V/R 1012874 NP_687143.1 CDS pyrG NC_004116.1 115920 117524 D CTP synthase; CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer; CTP synthetase 115920..117524 Streptococcus agalactiae 2603V/R 1012875 NP_687144.1 CDS SAG0108 NC_004116.1 117633 118559 D hypothetical protein 117633..118559 Streptococcus agalactiae 2603V/R 1012876 NP_687145.1 CDS dut NC_004116.1 118754 119200 D catalyzes the formation of dUMP from dUTP; deoxyuridine 5'-triphosphate nucleotidohydrolase 118754..119200 Streptococcus agalactiae 2603V/R 1012878 NP_687146.1 CDS radA NC_004116.1 119362 120726 D Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents; DNA repair protein RadA 119362..120726 Streptococcus agalactiae 2603V/R 1012879 NP_687147.1 CDS SAG0111 NC_004116.1 120862 121359 D carbonic anhydrase-like protein 120862..121359 Streptococcus agalactiae 2603V/R 1012880 NP_687148.1 CDS SAG0112 NC_004116.1 121513 122832 D Involved in disulfide oxidoreductase activity and electron transport; pyridine nucleotide-disulfide oxidoreductase 121513..122832 Streptococcus agalactiae 2603V/R 1012881 NP_687149.1 CDS gltX NC_004116.1 123041 124495 D Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation; glutamyl-tRNA synthetase 123041..124495 Streptococcus agalactiae 2603V/R 1012882 NP_687150.1 CDS rbsB NC_004116.1 124535 125503 R identified by match to PFAM protein family HMM PF00532; ribose ABC transporter periplasmic D-ribose-binding protein complement(124535..125503) Streptococcus agalactiae 2603V/R 1012883 NP_687151.1 CDS rbsC NC_004116.1 125556 126488 R identified by match to PFAM protein family HMM PF02653; ribose ABC transporter permease complement(125556..126488) Streptococcus agalactiae 2603V/R 1012884 NP_687152.1 CDS rbsA NC_004116.1 126499 127977 R identified by match to PFAM protein family HMM PF00005; ribose ABC transporter ATP-binding protein complement(126499..127977) Streptococcus agalactiae 2603V/R 1012885 NP_687153.1 CDS rbsD NC_004116.1 127993 128391 R cytoplasmic mutarotase that catalyzes the conversion between beta-pyran and beta-furan forms of D-ribose; RbsD is required for efficient ribose utilization in E. coli; rbsD-mutant E. coli strains are unable to use ribose as a sole carbon source; D-ribose pyranase complement(127993..128391) Streptococcus agalactiae 2603V/R 1012886 NP_687154.1 CDS rbsK NC_004116.1 128366 129277 R identified by match to PFAM protein family HMM PF00294; ribokinase complement(128366..129277) Streptococcus agalactiae 2603V/R 1012887 NP_687155.1 CDS rbsR NC_004116.1 129270 130256 R identified by match to PFAM protein family HMM PF00356; ribose operon repressor RbsR complement(129270..130256) Streptococcus agalactiae 2603V/R 1012888 NP_687156.1 CDS SAG0120 NC_004116.1 130314 130412 R hypothetical protein complement(130314..130412) Streptococcus agalactiae 2603V/R 1012889 NP_687157.1 CDS SAG0121 NC_004116.1 130438 131526 D identified by match to PFAM protein family HMM PF02687; permease 130438..131526 Streptococcus agalactiae 2603V/R 1012890 NP_687158.1 CDS SAG0122 NC_004116.1 131526 132212 D identified by match to PFAM protein family HMM PF00005; ABC transporter ATP-binding protein 131526..132212 Streptococcus agalactiae 2603V/R 1012891 NP_687159.1 CDS SAG0123 NC_004116.1 132243 132914 D identified by match to PFAM protein family HMM PF00072; DNA-binding response regulator 132243..132914 Streptococcus agalactiae 2603V/R 1012892 NP_687160.1 CDS SAG0124 NC_004116.1 132907 133977 D identified by match to PFAM protein family HMM PF00512; sensor histidine kinase 132907..133977 Streptococcus agalactiae 2603V/R 1012893 NP_687161.1 CDS argG NC_004116.1 134131 135321 D catalyzes the formation of 2-N(omega)-(L-arginino)succinate from L-citrulline and L-aspartate in arginine biosynthesis, AMP-forming; argininosuccinate synthase 134131..135321 Streptococcus agalactiae 2603V/R 1012894 NP_687162.1 CDS argH NC_004116.1 135340 136728 D catalyzes the formation of arginine from (N-L-arginino)succinate; argininosuccinate lyase 135340..136728 Streptococcus agalactiae 2603V/R 1012895 NP_687163.1 CDS fba NC_004116.1 136869 137750 D catalyzes the formation of glycerone phosphate and glyceraldehyde 3-phosphate from fructose 1,6, bisphosphate; fructose-bisphosphate aldolase 136869..137750 Streptococcus agalactiae 2603V/R 1012896 NP_687164.1 CDS SAG0128 NC_004116.1 137834 138751 R identified by match to PFAM protein family HMM PF00056; L-2-hydroxyisocaproate dehydrogenase complement(137834..138751) Streptococcus agalactiae 2603V/R 1012897 NP_687165.1 CDS rpmB NC_004116.1 138990 139178 D required for 70S ribosome assembly; 50S ribosomal protein L28 138990..139178 Streptococcus agalactiae 2603V/R 1012898 NP_687166.1 CDS SAG0130 NC_004116.1 139310 139675 D hypothetical protein 139310..139675 Streptococcus agalactiae 2603V/R 1012899 NP_687167.1 CDS SAG0131 NC_004116.1 139708 141339 D identified by match to PFAM protein family HMM PF02734; DAK2 domain-containing protein 139708..141339 Streptococcus agalactiae 2603V/R 1012900 NP_687168.1 CDS SAG0132 NC_004116.1 141487 142371 D identified by match to PFAM protein family HMM PF01145; The product of this gene was detected by Western blot analysis. For details on the method see Tettelin et al. 2002.; hypothetical protein 141487..142371 Streptococcus agalactiae 2603V/R 1012901 NP_687169.1 CDS SAG0133 NC_004116.1 142463 142579 R hypothetical protein complement(142463..142579) Streptococcus agalactiae 2603V/R 1012902 NP_687170.1 CDS SAG0134 NC_004116.1 142947 143237 R hypothetical protein complement(142947..143237) Streptococcus agalactiae 2603V/R 1012903 NP_687171.1 CDS SAG0135 NC_004116.1 143579 144319 R identified by match to PFAM protein family HMM PF00005; amino acid ABC transporter ATP-binding protein complement(143579..144319) Streptococcus agalactiae 2603V/R 1012904 NP_687172.1 CDS SAG0136 NC_004116.1 144329 145879 R identified by match to PFAM protein family HMM PF00497; amino acid ABC transporter amino acid-binding protein/permease complement(144329..145879) Streptococcus agalactiae 2603V/R 1012905 NP_687173.1 CDS SAG0137 NC_004116.1 146015 147898 D hypothetical protein 146015..147898 Streptococcus agalactiae 2603V/R 1012906 NP_687174.1 CDS uppP NC_004116.1 147944 148783 D BacA; phosphatase activity in Escherichia coli not kinase; involved in bacitracin resistance as bacitracin supposedly sequesters undecaprenyl disphosphate which reduces the pool of lipid carrier available to the cell; undecaprenyl pyrophosphate phosphatase 147944..148783 Streptococcus agalactiae 2603V/R 1012907 NP_687175.1 CDS SAG0139 NC_004116.1 148903 149658 D enables recognition and targeting of proteins for proteolysis, involved in negative regulation of competence; adaptor protein 148903..149658 Streptococcus agalactiae 2603V/R 1012908 NP_687176.1 CDS SAG0140 NC_004116.1 149660 150820 D identified by match to PFAM protein family HMM PF00953; glycoside hydrolase family protein 149660..150820 Streptococcus agalactiae 2603V/R 1012909 NP_687177.1 CDS SAG0141 NC_004116.1 150985 151755 D identified by match to PFAM protein family HMM PF00005; ABC transporter ATP-binding protein 150985..151755 Streptococcus agalactiae 2603V/R 1012910 NP_687178.1 CDS SAG0142 NC_004116.1 151792 153054 D hypothetical protein 151792..153054 Streptococcus agalactiae 2603V/R 1012911 NP_687179.1 CDS csdB NC_004116.1 153056 154288 D identified by match to PFAM protein family HMM PF00266; selenocysteine lyase 153056..154288 Streptococcus agalactiae 2603V/R 1012912 NP_687180.1 CDS SAG0144 NC_004116.1 154275 154718 D identified by match to PFAM protein family HMM PF01592; NifU family protein 154275..154718 Streptococcus agalactiae 2603V/R 1012913 NP_687181.1 CDS SAG0145 NC_004116.1 154818 156236 D hypothetical protein 154818..156236 Streptococcus agalactiae 2603V/R 1012914 NP_687182.1 CDS SAG0146 NC_004116.1 156308 157495 R identified by match to PFAM protein family HMM PF00768; penicillin-binding protein 4 complement(156308..157495) Streptococcus agalactiae 2603V/R 1012915 NP_687183.1 CDS SAG0147 NC_004116.1 157648 158883 R identified by match to PFAM protein family HMM PF00768; D-alanyl-D-alanine carboxypeptidase complement(157648..158883) Streptococcus agalactiae 2603V/R 1012916 NP_687184.1 CDS SAG0148 NC_004116.1 159124 160779 D identified by match to PFAM protein family HMM PF00496; oligopeptide ABC transporter substrate-binding protein 159124..160779 Streptococcus agalactiae 2603V/R 1012917 NP_687185.1 CDS SAG0149 NC_004116.1 160898 161812 D identified by match to PFAM protein family HMM PF00528; oligopeptide ABC transporter permease 160898..161812 Streptococcus agalactiae 2603V/R 1012918 NP_687186.1 CDS SAG0150 NC_004116.1 161822 162853 D identified by match to PFAM protein family HMM PF00528; oligopeptide ABC transporter permease 161822..162853 Streptococcus agalactiae 2603V/R 1012919 NP_687187.1 CDS SAG0151 NC_004116.1 162866 163912 D identified by match to PFAM protein family HMM PF00005; oligopeptide ABC transporter ATP-binding protein 162866..163912 Streptococcus agalactiae 2603V/R 1012920 NP_687188.1 CDS SAG0152 NC_004116.1 163912 164844 D identified by match to PFAM protein family HMM PF00005; oligopeptide ABC transporter ATP-binding protein 163912..164844 Streptococcus agalactiae 2603V/R 1012921 NP_687189.1 CDS ipk NC_004116.1 170382 171233 D An essential enzyme in the nonmevalonate pathway of isopentenyl diphosphate and dimethylallyl diphosphate biosynthesis; 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase 170382..171233 Streptococcus agalactiae 2603V/R 1012927 NP_687190.1 CDS adcR NC_004116.1 171319 171762 D identified by match to PFAM protein family HMM PF01047; adc operon repressor AdcR 171319..171762 Streptococcus agalactiae 2603V/R 1012928 NP_687191.1 CDS SAG0155 NC_004116.1 171765 172475 D identified by match to PFAM protein family HMM PF00005; zinc ABC transporter ATP-binding protein 171765..172475 Streptococcus agalactiae 2603V/R 1012929 NP_687192.1 CDS SAG0156 NC_004116.1 172465 173277 D identified by match to PFAM protein family HMM PF00950; zinc ABC transporter permease 172465..173277 Streptococcus agalactiae 2603V/R 1012930 NP_687193.1 CDS tyrS NC_004116.1 175097 176356 R catalyzes the formation of tyrosyl-tRNA(Tyr) from tyrosine and tRNA(Tyr); tyrosyl-tRNA synthetase complement(175097..176356) Streptococcus agalactiae 2603V/R 1012932 NP_687194.1 CDS SAG0159 NC_004116.1 176467 178764 D identified by match to PFAM protein family HMM PF00905; penicillin-binding protein 1B 176467..178764 Streptococcus agalactiae 2603V/R 1012933 NP_687195.1 CDS rpoB NC_004116.1 179288 182863 D DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme; DNA-directed RNA polymerase subunit beta 179288..182863 Streptococcus agalactiae 2603V/R 1012934 NP_687196.1 CDS rpoC NC_004116.1 182980 186630 D DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Subunit beta' binds to sigma factor allowing it to bind to the -10 region of the promoter; DNA-directed RNA polymerase subunit beta' 182980..186630 Streptococcus agalactiae 2603V/R 1012935 NP_687197.1 CDS SAG0162 NC_004116.1 186744 187109 D hypothetical protein 186744..187109 Streptococcus agalactiae 2603V/R 1012936 NP_687198.1 CDS cglA NC_004116.1 187282 188253 D identified by match to PFAM protein family HMM PF00437; competence protein CglA 187282..188253 Streptococcus agalactiae 2603V/R 1012937 NP_687199.1 CDS cglB NC_004116.1 188342 189190 D identified by match to PFAM protein family HMM PF00482; competence protein CglB 188342..189190 Streptococcus agalactiae 2603V/R 1012938 NP_687200.1 CDS SAG0165 NC_004116.1 189187 189642 D hypothetical protein 189187..189642 Streptococcus agalactiae 2603V/R 1012939 NP_687201.1 CDS SAG0166 NC_004116.1 189620 189991 D similar to OMNI:NTL01SPL0084; identified by sequence similarity; hypothetical protein 189620..189991 Streptococcus agalactiae 2603V/R 1012940 NP_687202.1 CDS SAG0167 NC_004116.1 190106 191080 D hypothetical protein 190106..191080 Streptococcus agalactiae 2603V/R 1012941 NP_687203.1 CDS ackA NC_004116.1 191112 192305 D AckA utilizes acetate and can acetylate CheY which increases signal strength during flagellar rotation; utilizes magnesium and ATP; also involved in conversion of acetate to aceyl-CoA; acetate kinase 191112..192305 Streptococcus agalactiae 2603V/R 1012942 NP_687204.1 CDS SAG0169 NC_004116.1 192457 192663 D identified by match to PFAM protein family HMM PF01381; Cro/CI family transcriptional regulator 192457..192663 Streptococcus agalactiae 2603V/R 1012943 NP_687205.1 CDS SAG0170 NC_004116.1 192722 192859 D hypothetical protein 192722..192859 Streptococcus agalactiae 2603V/R 1012944 NP_687206.1 CDS SAG0171 NC_004116.1 192900 193355 D hypothetical protein 192900..193355 Streptococcus agalactiae 2603V/R 1012945 NP_687207.1 CDS SAG0172 NC_004116.1 193424 194089 D identified by match to PFAM protein family HMM PF02517; protease 193424..194089 Streptococcus agalactiae 2603V/R 1012946 NP_687208.1 CDS proC NC_004116.1 194110 194880 R catalyzes the formation of L-proline from pyrroline-5-carboxylate; pyrroline-5-carboxylate reductase complement(194110..194880) Streptococcus agalactiae 2603V/R 1012947 NP_687209.1 CDS pepA NC_004116.1 194950 196017 R similar to PID:1072381; identified by sequence similarity; glutamyl-aminopeptidase complement(194950..196017) Streptococcus agalactiae 2603V/R 1012948 NP_687210.1 CDS SAG0175 NC_004116.1 196202 196441 R hypothetical protein complement(196202..196441) Streptococcus agalactiae 2603V/R 1012949 NP_687211.1 CDS SAG0176 NC_004116.1 196602 196886 D hypothetical protein 196602..196886 Streptococcus agalactiae 2603V/R 1012950 NP_687212.1 CDS SAG0177 NC_004116.1 196883 197206 D identified by match to PFAM protein family HMM PF00085; thioredoxin 196883..197206 Streptococcus agalactiae 2603V/R 1012951 NP_687213.1 CDS SAG0178 NC_004116.1 197239 197865 D identified by match to PFAM protein family HMM PF01588; tRNA-binding domain-containing protein 197239..197865 Streptococcus agalactiae 2603V/R 1012952 NP_687214.1 CDS SAG0179 NC_004116.1 197919 198635 R hypothetical protein complement(197919..198635) Streptococcus agalactiae 2603V/R 1012953 NP_687215.1 CDS ssb-1 NC_004116.1 198716 199111 D binds to single stranded DNA and may facilitate the binding and interaction of other proteins to DNA; single-stranded DNA-binding protein 198716..199111 Streptococcus agalactiae 2603V/R 1012954 NP_687216.1 CDS SAG0181 NC_004116.1 199235 199879 D identified by match to PFAM protein family HMM PF00702; HAD superfamily hydrolase 199235..199879 Streptococcus agalactiae 2603V/R 1012955 NP_687217.1 CDS SAG0182 NC_004116.1 199906 201651 D identified by match to PFAM protein family HMM PF02518; sensor histidine kinase 199906..201651 Streptococcus agalactiae 2603V/R 1012956 NP_687218.1 CDS SAG0183 NC_004116.1 201632 202372 D identified by match to PFAM protein family HMM PF00072; response regulator 201632..202372 Streptococcus agalactiae 2603V/R 1012957 NP_687219.1 CDS SAG0184 NC_004116.1 202542 202997 D hypothetical protein 202542..202997 Streptococcus agalactiae 2603V/R 1012958 NP_687220.1 CDS SAG0185 NC_004116.1 202999 203727 D hypothetical protein 202999..203727 Streptococcus agalactiae 2603V/R 1012959 NP_687221.1 CDS SAG0186 NC_004116.1 203839 203949 R hypothetical protein complement(203839..203949) Streptococcus agalactiae 2603V/R 1012960 NP_687222.1 CDS SAG0187 NC_004116.1 203970 205598 D identified by match to PFAM protein family HMM PF00496; oligopeptide ABC transporter oligopeptide-binding protein 203970..205598 Streptococcus agalactiae 2603V/R 1012961 NP_687223.1 CDS SAG0188 NC_004116.1 205711 206688 D identified by match to PFAM protein family HMM PF00528; oligopeptide ABC transporter permease 205711..206688 Streptococcus agalactiae 2603V/R 1012962 NP_687224.1 CDS SAG0189 NC_004116.1 206685 207506 D identified by match to PFAM protein family HMM PF00528; oligopeptide ABC transporter permease 206685..207506 Streptococcus agalactiae 2603V/R 1012963 NP_687225.1 CDS SAG0190 NC_004116.1 207518 208321 D identified by match to PFAM protein family HMM PF00005; peptide ABC transporter ATP-binding protein 207518..208321 Streptococcus agalactiae 2603V/R 1012964 NP_687226.1 CDS SAG0191 NC_004116.1 208305 208931 D identified by match to PFAM protein family HMM PF00005; peptide ABC transporter ATP-binding protein 208305..208931 Streptococcus agalactiae 2603V/R 1012965 NP_687227.1 CDS SAG0192 NC_004116.1 209214 211244 D identified by match to PFAM protein family HMM PF00358; PTS system transporter subunit IIABC 209214..211244 Streptococcus agalactiae 2603V/R 1012966 NP_687228.1 CDS SAG0193 NC_004116.1 211466 213091 D identified by match to PFAM protein family HMM PF00128; alpha amylase 211466..213091 Streptococcus agalactiae 2603V/R 1012967 NP_687229.1 CDS SAG0194 NC_004116.1 213307 215226 D identified by match to PFAM protein family HMM PF00359; BglG family transcriptional antiterminator 213307..215226 Streptococcus agalactiae 2603V/R 1012968 NP_687230.1 CDS SAG0195 NC_004116.1 215240 216373 R identified by match to PFAM protein family HMM PF01609; IS1548 transposase complement(215240..216373) Streptococcus agalactiae 2603V/R 1012969 NP_687231.1 CDS SAG0196 NC_004116.1 216468 216668 D similar to OMNI:SP2131; identified by sequence similarity; hypothetical protein 216468..216668 Streptococcus agalactiae 2603V/R 1012970 NP_687232.1 CDS SAG0197 NC_004116.1 216671 216955 D similar to OMNI:SP2130; identified by sequence similarity; PTS system transporter subunit IIB 216671..216955 Streptococcus agalactiae 2603V/R 1012971 NP_687233.1 CDS ulaA NC_004116.1 216968 218323 D membrane component; functions with enzymes IIB (sgaB; ulaB) and IIA (sgaA; ulaC) enzyme I and HPr for anaerobic utilization and uptake of L-ascorbate; sgaTBA are regulated by yifQ as well as Crp and Fnr; PTS system ascorbate-specific transporter subunit IIC 216968..218323 Streptococcus agalactiae 2603V/R 1012972 NP_687234.1 CDS SAG0199 NC_004116.1 218326 219183 D identified by match to PFAM protein family HMM PF00456; transketolase 218326..219183 Streptococcus agalactiae 2603V/R 1012973 NP_687235.1 CDS SAG0200 NC_004116.1 219180 220109 D identified by match to PFAM protein family HMM PF02779; transketolase 219180..220109 Streptococcus agalactiae 2603V/R 1012974 NP_687236.1 CDS SAG0201 NC_004116.1 220218 221477 D identified by match to PFAM protein family HMM PF00175; oxidoreductase 220218..221477 Streptococcus agalactiae 2603V/R 1012975 NP_687237.1 CDS rpsO NC_004116.1 221565 221834 D primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence; 30S ribosomal protein S15 221565..221834 Streptococcus agalactiae 2603V/R 1012976 NP_687238.1 CDS pnp NC_004116.1 222215 224344 D identified by match to PFAM protein family HMM PF00013; polynucleotide phosphorylase 222215..224344 Streptococcus agalactiae 2603V/R 1012977 NP_687239.1 CDS SAG0204 NC_004116.1 224346 225098 D hypothetical protein 224346..225098 Streptococcus agalactiae 2603V/R 1012978 NP_687240.1 CDS cysE NC_004116.1 225107 225691 D identified by match to PFAM protein family HMM PF00132; serine O-acetyltransferase 225107..225691 Streptococcus agalactiae 2603V/R 1012979 NP_687241.1 CDS SAG0206 NC_004116.1 225701 225883 D lipoprotein 225701..225883 Streptococcus agalactiae 2603V/R 1012980 NP_687242.1 CDS cysS NC_004116.1 225880 227223 D catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA; cysteinyl-tRNA synthetase 225880..227223 Streptococcus agalactiae 2603V/R 1012981 NP_687243.1 CDS SAG0208 NC_004116.1 227216 227602 D hypothetical protein 227216..227602 Streptococcus agalactiae 2603V/R 1012982 NP_687244.1 CDS SAG0209 NC_004116.1 227705 228460 D identified by match to PFAM protein family HMM PF00588; RNA methyltransferase 227705..228460 Streptococcus agalactiae 2603V/R 1012983 NP_687245.1 CDS SAG0210 NC_004116.1 228457 228975 D hypothetical protein 228457..228975 Streptococcus agalactiae 2603V/R 1012984 NP_687246.1 CDS SAG0211 NC_004116.1 229068 229928 D identified by match to PFAM protein family HMM PF02645; DegV family protein 229068..229928 Streptococcus agalactiae 2603V/R 1012985 NP_687247.1 CDS SAG0212 NC_004116.1 230061 230159 D hypothetical protein 230061..230159 Streptococcus agalactiae 2603V/R 1012986 NP_687248.1 CDS SAG0213 NC_004116.1 230273 230392 D hypothetical protein 230273..230392 Streptococcus agalactiae 2603V/R 1012987 NP_687249.1 CDS rplM NC_004116.1 230809 231255 D in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit; 50S ribosomal protein L13 230809..231255 Streptococcus agalactiae 2603V/R 1012988 NP_687250.1 CDS rpsI NC_004116.1 231276 231668 D forms a direct contact with the tRNA during translation; 30S ribosomal protein S9 231276..231668 Streptococcus agalactiae 2603V/R 1012989 NP_687251.1 CDS SAG0216 NC_004116.1 231682 231783 R hypothetical protein complement(231682..231783) Streptococcus agalactiae 2603V/R 1012990 NP_687252.1 CDS SAG0217 NC_004116.1 231796 232950 R identified by match to PFAM protein family HMM PF00589; phage integrase family site specific recombinase complement(231796..232950) Streptococcus agalactiae 2603V/R 1012991 NP_687253.1 CDS SAG0218 NC_004116.1 233015 233491 R identified by match to PFAM protein family HMM PF01381; Cro/CI family transcriptional regulator complement(233015..233491) Streptococcus agalactiae 2603V/R 1012992 NP_687254.1 CDS SAG0219 NC_004116.1 233645 233950 D hypothetical protein 233645..233950 Streptococcus agalactiae 2603V/R 1012993 NP_687255.1 CDS SAG0220 NC_004116.1 234087 234365 D hypothetical protein 234087..234365 Streptococcus agalactiae 2603V/R 1012994 NP_687256.1 CDS SAG0221 NC_004116.1 234376 234606 D hypothetical protein 234376..234606 Streptococcus agalactiae 2603V/R 1012995 NP_687257.1 CDS SAG0222 NC_004116.1 234619 234945 D similar to OMNI:EFC0001; identified by sequence similarity; hypothetical protein 234619..234945 Streptococcus agalactiae 2603V/R 1012996 NP_687258.1 CDS SAG0223 NC_004116.1 234949 235578 D hypothetical protein 234949..235578 Streptococcus agalactiae 2603V/R 1012997 NP_687259.1 CDS SAG0224 NC_004116.1 235768 236766 D identified by match to PFAM protein family HMM PF02486; replication initiation protein 235768..236766 Streptococcus agalactiae 2603V/R 1012998 NP_687260.1 CDS SAG0225 NC_004116.1 236802 237236 D hypothetical protein 236802..237236 Streptococcus agalactiae 2603V/R 1012999 NP_687261.1 CDS SAG0226 NC_004116.1 237552 238808 D identified by match to PFAM protein family HMM PF01076; recombination protein 237552..238808 Streptococcus agalactiae 2603V/R 1013000 NP_687262.1 CDS SAG0227 NC_004116.1 238976 239446 D hypothetical protein 238976..239446 Streptococcus agalactiae 2603V/R 1013001 NP_687263.1 CDS SAG0228 NC_004116.1 239751 240086 R hypothetical protein complement(239751..240086) Streptococcus agalactiae 2603V/R 1013002 NP_687264.1 CDS SAG0229 NC_004116.1 240076 240363 R hypothetical protein complement(240076..240363) Streptococcus agalactiae 2603V/R 1013003 NP_687265.1 CDS SAG0230 NC_004116.1 240870 241160 D hypothetical protein 240870..241160 Streptococcus agalactiae 2603V/R 1013004 NP_687266.1 CDS SAG0231 NC_004116.1 241262 241669 D hypothetical protein 241262..241669 Streptococcus agalactiae 2603V/R 1013005 NP_687267.1 CDS SAG0232 NC_004116.1 241669 242229 D hypothetical protein 241669..242229 Streptococcus agalactiae 2603V/R 1013006 NP_687268.1 CDS SAG0233 NC_004116.1 242202 242882 D hypothetical protein 242202..242882 Streptococcus agalactiae 2603V/R 1013007 NP_687269.1 CDS SAG0234 NC_004116.1 242867 243253 D hypothetical protein 242867..243253 Streptococcus agalactiae 2603V/R 1013008 NP_687270.1 CDS SAG0235 NC_004116.1 243287 243568 D hypothetical protein 243287..243568 Streptococcus agalactiae 2603V/R 1013009 NP_687271.1 CDS SAG0236 NC_004116.1 243659 243757 D hypothetical protein 243659..243757 Streptococcus agalactiae 2603V/R 1013010 NP_687272.1 CDS SAG0237 NC_004116.1 244185 244289 D hypothetical protein 244185..244289 Streptococcus agalactiae 2603V/R 1013011 NP_687273.1 CDS SAG0238 NC_004116.1 244286 244411 D hypothetical protein 244286..244411 Streptococcus agalactiae 2603V/R 1013012 NP_687274.1 CDS SAG0239 NC_004116.1 244411 245271 D MutR family transcriptional regulator 244411..245271 Streptococcus agalactiae 2603V/R 1013013 NP_687275.1 CDS SAG0240 NC_004116.1 245344 246525 D transporter 245344..246525 Streptococcus agalactiae 2603V/R 1013014 NP_687276.1 CDS SAG0241 NC_004116.1 246587 247228 R identified by match to PFAM protein family HMM PF00528; amino acid ABC transporter permease complement(246587..247228) Streptococcus agalactiae 2603V/R 1013015 NP_687277.1 CDS SAG0242 NC_004116.1 247238 248164 R similar to GB:AL009126; identified by sequence similarity; amino acid ABC transporter amino acid-binding protein complement(247238..248164) Streptococcus agalactiae 2603V/R 1013016 NP_687278.1 CDS SAG0243 NC_004116.1 248167 248802 R identified by match to PFAM protein family HMM PF00528; amino acid ABC transporter permease complement(248167..248802) Streptococcus agalactiae 2603V/R 1013017 NP_687279.1 CDS SAG0244 NC_004116.1 248802 249947 R identified by match to PFAM protein family HMM PF00005; amino acid ABC transporter ATP-binding protein complement(248802..249947) Streptococcus agalactiae 2603V/R 1013018 NP_687280.1 CDS SAG0245 NC_004116.1 256634 257092 D identified by Glimmer2; The product of this gene was detected by Western blot analysis. For details on the method see Tettelin et al. 2002.; hypothetical protein 256634..257092 Streptococcus agalactiae 2603V/R 1013034 NP_687281.1 CDS SAG0246 NC_004116.1 257156 257962 D hypothetical protein 257156..257962 Streptococcus agalactiae 2603V/R 1013035 NP_687282.1 CDS SAG0247 NC_004116.1 258440 258790 D hypothetical protein 258440..258790 Streptococcus agalactiae 2603V/R 1013036 NP_687283.1 CDS SAG0248 NC_004116.1 258809 259081 D hypothetical protein 258809..259081 Streptococcus agalactiae 2603V/R 1013037 NP_687284.1 CDS SAG0249 NC_004116.1 259091 259441 D hypothetical protein 259091..259441 Streptococcus agalactiae 2603V/R 1013038 NP_687285.1 CDS SAG0250 NC_004116.1 260302 260883 D hypothetical protein 260302..260883 Streptococcus agalactiae 2603V/R 1013039 NP_687286.1 CDS SAG0251 NC_004116.1 260886 261104 D identified by match to PFAM protein family HMM PF01381; Cro/CI family transcriptional regulator 260886..261104 Streptococcus agalactiae 2603V/R 1013040 NP_687287.1 CDS SAG0252 NC_004116.1 261677 262237 D identified by match to PFAM protein family HMM PF00583; acetyltransferase 261677..262237 Streptococcus agalactiae 2603V/R 1013041 NP_687288.1 CDS SAG0253 NC_004116.1 262337 262915 D identified by match to PFAM protein family HMM PF00583; acetyltransferase 262337..262915 Streptococcus agalactiae 2603V/R 1013042 NP_687289.1 CDS SAG0254 NC_004116.1 262958 263638 D identified by match to PFAM protein family HMM PF00583; acetyltransferase 262958..263638 Streptococcus agalactiae 2603V/R 1013043 NP_687290.1 CDS SAG0255 NC_004116.1 263898 264845 R hypothetical protein complement(263898..264845) Streptococcus agalactiae 2603V/R 1013044 NP_687291.1 CDS SAG0256 NC_004116.1 264842 265333 R identified by match to PFAM protein family HMM PF00776; ECF subfamily RNA polymerase sigma factor complement(264842..265333) Streptococcus agalactiae 2603V/R 1013045 NP_687292.1 CDS SAG0257 NC_004116.1 265617 265778 D lipoprotein 265617..265778 Streptococcus agalactiae 2603V/R 1013046 NP_687293.1 CDS SAG0258 NC_004116.1 265913 266521 R identified by match to PFAM protein family HMM PF00440; TetR family transcriptional regulator complement(265913..266521) Streptococcus agalactiae 2603V/R 1013047 NP_687294.1 CDS SAG0259 NC_004116.1 266545 267642 R ABC transporter complement(266545..267642) Streptococcus agalactiae 2603V/R 1013048 NP_687295.1 CDS SAG0260 NC_004116.1 267645 268361 R identified by match to PFAM protein family HMM PF00005; ABC transporter ATP-binding protein complement(267645..268361) Streptococcus agalactiae 2603V/R 1013049 NP_687296.1 CDS SAG0261 NC_004116.1 268657 269046 R identified by match to PFAM protein family HMM PF01609; IS1381 transposase protein B complement(268657..269046) Streptococcus agalactiae 2603V/R 1013050 NP_687297.1 CDS SAG0262 NC_004116.1 269079 269462 R similar to OMNI:SP0537; identified by sequence similarity; IS1381 transposase protein A complement(269079..269462) Streptococcus agalactiae 2603V/R 1013051 NP_687298.1 CDS SAG0263 NC_004116.1 269498 270013 R hypothetical protein complement(269498..270013) Streptococcus agalactiae 2603V/R 1013052 NP_687299.1 CDS SAG0264 NC_004116.1 270190 270501 R hypothetical protein complement(270190..270501) Streptococcus agalactiae 2603V/R 1013053 NP_687300.1 CDS SAG0265 NC_004116.1 270693 271400 D identified by Glimmer2; The product of this gene was detected by Western blot analysis. For details on the method see Tettelin et al. 2002.; hypothetical protein 270693..271400 Streptococcus agalactiae 2603V/R 1013054 NP_687301.1 CDS nagA NC_004116.1 271678 272826 D identified by match to PFAM protein family HMM PF02612; N-acetylglucosamine-6-phosphate deacetylase 271678..272826 Streptococcus agalactiae 2603V/R 1013055 NP_687302.1 CDS SAG0267 NC_004116.1 272945 273487 D hypothetical protein 272945..273487 Streptococcus agalactiae 2603V/R 1013056 NP_687303.1 CDS glyQ NC_004116.1 273800 274714 D glycine--tRNA ligase alpha chain; GlyRS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; glycyl-tRNA synthetase subunit alpha 273800..274714 Streptococcus agalactiae 2603V/R 1013057 NP_687304.1 CDS SAG0269 NC_004116.1 274714 275355 D ACP phosphodieterase 274714..275355 Streptococcus agalactiae 2603V/R 1013058 NP_687305.1 CDS glyS NC_004116.1 275359 277398 D glycine--tRNA ligase beta chain; glyS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; glycyl-tRNA synthetase subunit beta 275359..277398 Streptococcus agalactiae 2603V/R 1013059 NP_687306.1 CDS SAG0271 NC_004116.1 277410 277667 D hypothetical protein 277410..277667 Streptococcus agalactiae 2603V/R 1013060 NP_687307.1 CDS SAG0272 NC_004116.1 277756 278019 D similar to OMNI:NTL01SPL1075; identified by sequence similarity; hypothetical protein 277756..278019 Streptococcus agalactiae 2603V/R 1013061 NP_687308.1 CDS glpK NC_004116.1 278134 279642 D Converts glycerol and ADP to glycerol-3-phosphate and ADP; glycerol kinase 278134..279642 Streptococcus agalactiae 2603V/R 1013062 NP_687309.1 CDS SAG0274 NC_004116.1 279655 281484 D identified by match to PFAM protein family HMM PF01224; alpha-glycerophosphate oxidase 279655..281484 Streptococcus agalactiae 2603V/R 1013063 NP_687310.1 CDS glpF-1 NC_004116.1 281496 282194 D identified by match to PFAM protein family HMM PF00230; glycerol uptake facilitator protein 281496..282194 Streptococcus agalactiae 2603V/R 1013064 NP_687311.1 CDS SAG0276 NC_004116.1 282282 283619 D identified by match to PFAM protein family HMM PF00070; NADH oxidase 282282..283619 Streptococcus agalactiae 2603V/R 1013065 NP_687312.1 CDS SAG0277 NC_004116.1 283610 285040 D hypothetical protein 283610..285040 Streptococcus agalactiae 2603V/R 1013066 NP_687313.1 CDS tkt NC_004116.1 285165 287150 D catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase; transketolase 285165..287150 Streptococcus agalactiae 2603V/R 1013067 NP_687314.1 CDS SAG0279 NC_004116.1 287363 287668 D hypothetical protein 287363..287668 Streptococcus agalactiae 2603V/R 1013068 NP_687315.1 CDS SAG0280 NC_004116.1 287688 288422 D identified by match to PFAM protein family HMM PF00005; ABC transporter ATP-binding protein 287688..288422 Streptococcus agalactiae 2603V/R 1013069 NP_687316.1 CDS SAG0281 NC_004116.1 288426 290030 D similar to OMNI:NTL01SPL1317; identified by sequence similarity; hypothetical protein 288426..290030 Streptococcus agalactiae 2603V/R 1013070 NP_687317.1 CDS SAG0282 NC_004116.1 290238 291623 R identified by match to PFAM protein family HMM PF00367; PTS system transporter subunit IIBC complement(290238..291623) Streptococcus agalactiae 2603V/R 1013071 NP_687318.1 CDS proB NC_004116.1 291764 292567 D catalyzes the formation of glutamate 5-phosphate from glutamate in proline biosynthesis; gamma-glutamyl kinase 291764..292567 Streptococcus agalactiae 2603V/R 1013072 NP_687319.1 CDS proA NC_004116.1 292577 293830 D Catalyzes the phosphorylation of L-glutamate during the proline biosynthesis pathway; gamma-glutamyl phosphate reductase 292577..293830 Streptococcus agalactiae 2603V/R 1013073 NP_687320.2 CDS mraW NC_004116.1 293913 294860 D S-adenosyl-methyltransferase MraW 293913..294860 Streptococcus agalactiae 2603V/R 1013074 NP_687321.1 CDS SAG0286 NC_004116.1 294875 295201 D similar to OMNI:SP0335; identified by sequence similarity; cell division protein FtsL 294875..295201 Streptococcus agalactiae 2603V/R 1013075 NP_687322.1 CDS pbpX NC_004116.1 295205 297463 D identified by match to PFAM protein family HMM PF00905; penicillin-binding protein 2X 295205..297463 Streptococcus agalactiae 2603V/R 1013076 NP_687323.1 CDS mraY NC_004116.1 297465 298475 D First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; phospho-N-acetylmuramoyl-pentapeptide- transferase 297465..298475 Streptococcus agalactiae 2603V/R 1013077 NP_687324.1 CDS SAG0289 NC_004116.1 298573 299916 D identified by match to PFAM protein family HMM PF00270; DEAD/DEAH box helicase 298573..299916 Streptococcus agalactiae 2603V/R 1013078 NP_687325.1 CDS SAG0290 NC_004116.1 300054 300866 D identified by match to PFAM protein family HMM PF00497; ABC transporter substrate-binding protein 300054..300866 Streptococcus agalactiae 2603V/R 1013079 NP_687326.1 CDS SAG0291 NC_004116.1 300961 301764 D identified by match to PFAM protein family HMM PF00528; amino acid ABC transporter permease 300961..301764 Streptococcus agalactiae 2603V/R 1013080 NP_687327.1 CDS SAG0292 NC_004116.1 301764 302507 D identified by match to PFAM protein family HMM PF00005; amino acid ABC transporter ATP-binding protein 301764..302507 Streptococcus agalactiae 2603V/R 1013081 NP_687328.1 CDS SAG0293 NC_004116.1 302629 302853 D hypothetical protein 302629..302853 Streptococcus agalactiae 2603V/R 1013082 NP_687329.1 CDS trxB NC_004116.1 302922 303836 D identified by match to PFAM protein family HMM PF00070; thioredoxin reductase 302922..303836 Streptococcus agalactiae 2603V/R 1013083 NP_687330.1 CDS SAG0295 NC_004116.1 303994 305454 D catalyzes the formation of 5-phospho-alpha-D-ribose 1-diphosphate and nicotinate from nicotinate D-ribonucleotide and diphosphate; nicotinate phosphoribosyltransferase 303994..305454 Streptococcus agalactiae 2603V/R 1013084 NP_687331.1 CDS nadE NC_004116.1 305451 306272 D catalyzes the formation of nicotinamide adenine dinucleotide (NAD) from nicotinic acid adenine dinucleotide (NAAD) using either ammonia or glutamine as the amide donor and ATP; ammonia-utilizing enzymes include the ones from Bacillus and Escherichia coli while glutamine-utilizing enzymes include the Mycobacterial one; forms homodimers; NAD synthetase 305451..306272 Streptococcus agalactiae 2603V/R 1013085 NP_687332.1 CDS pepC NC_004116.1 306385 307719 D identified by match to PFAM protein family HMM PF03051; aminopeptidase 306385..307719 Streptococcus agalactiae 2603V/R 1013086 NP_687333.1 CDS pbp1A NC_004116.1 307765 310017 R identified by match to PFAM protein family HMM PF00905; penicillin-binding protein 1A complement(307765..310017) Streptococcus agalactiae 2603V/R 1013087 NP_687334.1 CDS recU NC_004116.1 310004 310603 R functions in homologous recombination, DNA repair, and chromosome segregation; binds preferentially to three- and four-stranded DNA intermediates; introduces specific nick sites in four-stranded DNA substrates; functions similarly to Escherichia coli RuvC; Holliday junction-specific endonuclease complement(310004..310603) Streptococcus agalactiae 2603V/R 1013088 NP_687335.1 CDS SAG0300 NC_004116.1 310678 311196 D hypothetical protein 310678..311196 Streptococcus agalactiae 2603V/R 1013089 NP_687336.1 CDS SAG0301 NC_004116.1 311177 311299 D hypothetical protein 311177..311299 Streptococcus agalactiae 2603V/R 1013090 NP_687337.1 CDS SAG0302 NC_004116.1 311317 311649 D GpsB; guiding PBP1 shuttling; similar to DivIVA; cell division protein GpsB 311317..311649 Streptococcus agalactiae 2603V/R 1013091 NP_687338.1 CDS SAG0303 NC_004116.1 312119 313273 D hypothetical protein 312119..313273 Streptococcus agalactiae 2603V/R 1013092 NP_687339.1 CDS SAG0304 NC_004116.1 313286 314749 D hypothetical protein 313286..314749 Streptococcus agalactiae 2603V/R 1013093 NP_687340.1 CDS luxS NC_004116.1 314974 315456 R catalyzes the hydrolysis of S-ribosylhomocysteine to homocysteine and autoinducer-2; S-ribosylhomocysteinase complement(314974..315456) Streptococcus agalactiae 2603V/R 1013094 NP_687341.1 CDS SAG0306 NC_004116.1 315645 317252 D identified by match to PFAM protein family HMM PF00013; hypothetical protein 315645..317252 Streptococcus agalactiae 2603V/R 1013095 NP_687342.1 CDS SAG0307 NC_004116.1 317299 317400 D hypothetical protein 317299..317400 Streptococcus agalactiae 2603V/R 1013096 NP_687343.1 CDS SAG0308 NC_004116.1 317381 318277 D identified by match to PFAM protein family HMM PF00005; ABC transporter ATP-binding protein 317381..318277 Streptococcus agalactiae 2603V/R 1013097 NP_687344.1 CDS SAG0309 NC_004116.1 318264 319004 D hypothetical protein 318264..319004 Streptococcus agalactiae 2603V/R 1013098 NP_687345.1 CDS SAG0310 NC_004116.1 319001 320086 D hypothetical protein 319001..320086 Streptococcus agalactiae 2603V/R 1013099 NP_687346.1 CDS SAG0312 NC_004116.1 320728 321432 D hypothetical protein 320728..321432 Streptococcus agalactiae 2603V/R 1013101 NP_687347.1 CDS gmk NC_004116.1 321599 322228 D Essential for recycling GMP and indirectly, cGMP; guanylate kinase 321599..322228 Streptococcus agalactiae 2603V/R 1013102 NP_687348.1 CDS SAG0314 NC_004116.1 322251 322565 D Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits; DNA-directed RNA polymerase subunit omega 322251..322565 Streptococcus agalactiae 2603V/R 1013103 NP_687349.1 CDS priA NC_004116.1 322639 325029 D binding of PriA to forked DNA starts the assembly of the primosome, also possesses 3'-5' helicase activity; primosome assembly protein PriA 322639..325029 Streptococcus agalactiae 2603V/R 1013104 NP_687350.1 CDS fmt NC_004116.1 325076 326011 D modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet) which is important in translation initiation; inactivation of this gene in Escherichia coli severely impairs growth; methionyl-tRNA formyltransferase 325076..326011 Streptococcus agalactiae 2603V/R 1013105 NP_687351.1 CDS sun NC_004116.1 326001 327323 D identified by match to PFAM protein family HMM PF01029; sun protein 326001..327323 Streptococcus agalactiae 2603V/R 1013106 NP_687352.1 CDS SAG0318 NC_004116.1 327361 328098 D identified by match to PFAM protein family HMM PF00481; serine/threonine phosphatase 327361..328098 Streptococcus agalactiae 2603V/R 1013107 NP_687353.1 CDS SAG0319 NC_004116.1 328098 330053 D identified by match to PFAM protein family HMM PF00069; serine/threonine protein kinase 328098..330053 Streptococcus agalactiae 2603V/R 1013108 NP_687354.1 CDS SAG0320 NC_004116.1 330214 330909 D hypothetical protein 330214..330909 Streptococcus agalactiae 2603V/R 1013109 NP_687355.1 CDS SAG0321 NC_004116.1 330906 331925 D identified by match to PFAM protein family HMM PF02518; sensor histidine kinase 330906..331925 Streptococcus agalactiae 2603V/R 1013110 NP_687356.1 CDS SAG0322 NC_004116.1 331918 332559 D identified by match to PFAM protein family HMM PF00072; DNA-binding response regulator 331918..332559 Streptococcus agalactiae 2603V/R 1013111 NP_687357.1 CDS SAG0323 NC_004116.1 332601 334001 D identified by match to PFAM protein family HMM PF00160; peptidyl-prolyl cis-trans isomerase 332601..334001 Streptococcus agalactiae 2603V/R 1013112 NP_687358.1 CDS SAG0324 NC_004116.1 333985 334359 D identified by match to PFAM protein family HMM PF00575; hypothetical protein 333985..334359 Streptococcus agalactiae 2603V/R 1013113 NP_687359.1 CDS pflA-1 NC_004116.1 334406 335182 R identified by match to PFAM protein family HMM PF02143; pyruvate formate-lyase-activating enzyme complement(334406..335182) Streptococcus agalactiae 2603V/R 1013114 NP_687360.1 CDS SAG0326 NC_004116.1 335303 336058 D identified by match to PFAM protein family HMM PF00455; DeoR family transcriptional regulator 335303..336058 Streptococcus agalactiae 2603V/R 1013115 NP_687361.1 CDS SAG0327 NC_004116.1 336177 337160 D transcriptional regulator 336177..337160 Streptococcus agalactiae 2603V/R 1013116 NP_687362.1 CDS celC NC_004116.1 337364 337687 D identified by match to PFAM protein family HMM PF02255; PTS system cellobiose-specific transporter subunit IIA 337364..337687 Streptococcus agalactiae 2603V/R 1013117 NP_687363.1 CDS SAG0329 NC_004116.1 337704 338024 D identified by match to PFAM protein family HMM PF02302; PTS system cellobiose-specific transporter subunit IIB 337704..338024 Streptococcus agalactiae 2603V/R 1013118 NP_687364.1 CDS celB NC_004116.1 338026 339327 D identified by match to PFAM protein family HMM PF02378; PTS system cellobiose-specific transporter subunit IIC 338026..339327 Streptococcus agalactiae 2603V/R 1013119 NP_687365.1 CDS pflD-1 NC_004116.1 339508 341964 D identified by match to PFAM protein family HMM PF01228; formate acetyltransferase 339508..341964 Streptococcus agalactiae 2603V/R 1013120 NP_687366.1 CDS SAG0332 NC_004116.1 341974 342642 D similar to transaldolase from Escherichia coli; many organisms have multiple copies; fructose-6-phosphate aldolase 341974..342642 Streptococcus agalactiae 2603V/R 1013121 NP_687367.1 CDS gldA NC_004116.1 342710 343798 D forms dimers and octamers; involved in conversion of glycerol to dihydroxy-acetone; glycerol dehydrogenase 342710..343798 Streptococcus agalactiae 2603V/R 1013122 NP_687368.1 CDS cysK NC_004116.1 343950 344876 R identified by match to PFAM protein family HMM PF00291; cysteine synthase A complement(343950..344876) Streptococcus agalactiae 2603V/R 1013123 NP_687369.1 CDS SAG0335 NC_004116.1 344967 345611 R hypothetical protein complement(344967..345611) Streptococcus agalactiae 2603V/R 1013124 NP_687370.1 CDS SAG0336 NC_004116.1 345667 346956 D identified by match to PFAM protein family HMM PF00270; helicase 345667..346956 Streptococcus agalactiae 2603V/R 1013125 NP_687371.1 CDS SAG0337 NC_004116.1 346956 347621 D competence protein F 346956..347621 Streptococcus agalactiae 2603V/R 1013126 NP_687372.1 CDS yfiA NC_004116.1 347698 348252 D identified by match to PFAM protein family HMM PF02482; ribosomal subunit interface protein 347698..348252 Streptococcus agalactiae 2603V/R 1013127 NP_687373.1 CDS SAG0339 NC_004116.1 353792 355144 R catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP; lysine and threonine sensitive; aspartate kinase complement(353792..355144) Streptococcus agalactiae 2603V/R 1013133 NP_687374.1 CDS SAG0340 NC_004116.1 355238 355888 D identified by match to PFAM protein family HMM PF00702; HAD superfamily hydrolase 355238..355888 Streptococcus agalactiae 2603V/R 1013134 NP_687375.1 CDS SAG0341 NC_004116.1 355874 356023 R hypothetical protein complement(355874..356023) Streptococcus agalactiae 2603V/R 1013135 NP_687376.1 CDS SAG0342 NC_004116.1 356025 356816 D Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; enoyl-CoA hydratase 356025..356816 Streptococcus agalactiae 2603V/R 1013136 NP_687377.1 CDS SAG0343 NC_004116.1 356912 357346 D identified by match to PFAM protein family HMM PF01047; MarR family transcriptional regulator 356912..357346 Streptococcus agalactiae 2603V/R 1013137 NP_687378.1 CDS fabH NC_004116.1 357346 358317 D FabH; beta-ketoacyl-acyl carrier protein synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs; 3-oxoacyl-ACP synthase 357346..358317 Streptococcus agalactiae 2603V/R 1013138 NP_687379.1 CDS acpP NC_004116.1 358375 358599 D carries the fatty acid chain in fatty acid biosynthesis; acyl carrier protein 358375..358599 Streptococcus agalactiae 2603V/R 1013139 NP_687380.1 CDS fabK NC_004116.1 358754 359713 D identified by match to PFAM protein family HMM PF03060; enoyl-ACP reductase 358754..359713 Streptococcus agalactiae 2603V/R 1013140 NP_687381.1 CDS fabD NC_004116.1 359733 360659 D identified by match to PFAM protein family HMM PF00698; ACP S-malonyltransferase 359733..360659 Streptococcus agalactiae 2603V/R 1013141 NP_687382.1 CDS fabG NC_004116.1 360668 361402 D catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis; 3-ketoacyl-ACP reductase 360668..361402 Streptococcus agalactiae 2603V/R 1013142 NP_687383.1 CDS fabF NC_004116.1 361418 362650 D FabF; beta-ketoacyl-ACP synthase II, KASII; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP; 3-oxoacyl-ACP synthase 361418..362650 Streptococcus agalactiae 2603V/R 1013143 NP_687384.1 CDS accB NC_004116.1 362652 363152 D composes the biotin carboxyl carrier protein subunit of the acetyl-CoA carboxylase complex, the enzyme that catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, which in turn controls the rate of fatty acid metabolism; acetyl-CoA carboxylase biotin carboxyl carrier protein subunit 362652..363152 Streptococcus agalactiae 2603V/R 1013144 NP_687385.1 CDS fabZ NC_004116.1 363149 363571 D in Pseudomonas aeruginosa this enzyme is a trimer of dimers; essential for membrane formation; performs third step of type II fatty acid biosynthesis; catalyzes dehydration of (3R)-hydroxyacyl-ACP to trans-2-acyl-ACP; (3R)-hydroxymyristoyl-ACP dehydratase 363149..363571 Streptococcus agalactiae 2603V/R 1013145 NP_687386.1 CDS accC NC_004116.1 363609 364979 D an AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism; acetyl-CoA carboxylase biotin carboxylase subunit 363609..364979 Streptococcus agalactiae 2603V/R 1013146 NP_687387.1 CDS accD NC_004116.1 364988 365863 D catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer of AccA2D2 subunits; acetyl-CoA carboxylase subunit beta 364988..365863 Streptococcus agalactiae 2603V/R 1013147 NP_687388.1 CDS accA NC_004116.1 365856 366629 D catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer composed of two alpha (AccA) and two beta (AccD) subunits; one of the two catalytic subunits that can form the acetyl CoA carboxylase enzyme together with a carrier protein; these proteins present a shorter N-terminus; acetyl-CoA carboxylase subunit alpha 365856..366629 Streptococcus agalactiae 2603V/R 1013148 NP_687389.1 CDS SAG0355 NC_004116.1 367099 367731 D hypothetical protein 367099..367731 Streptococcus agalactiae 2603V/R 1013149 NP_687390.1 CDS serS NC_004116.1 367777 369054 R catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; seryl-tRNA synthetase complement(367777..369054) Streptococcus agalactiae 2603V/R 1013150 NP_687391.1 CDS SAG0357 NC_004116.1 369420 370412 D hypothetical protein 369420..370412 Streptococcus agalactiae 2603V/R 1013151 NP_687392.1 CDS SAG0358 NC_004116.1 370450 370812 R hypothetical protein complement(370450..370812) Streptococcus agalactiae 2603V/R 1013152 NP_687393.1 CDS SAG0359 NC_004116.1 370931 371842 R PTS system mannose-specific transporter subunit IID complement(370931..371842) Streptococcus agalactiae 2603V/R 1013153 NP_687394.1 CDS manM NC_004116.1 371857 372669 R PTS system mannose-specific transporter subunit IIC complement(371857..372669) Streptococcus agalactiae 2603V/R 1013154 NP_687395.1 CDS manL NC_004116.1 372702 373712 R PTS system mannose-specific transporter subunit IIAB complement(372702..373712) Streptococcus agalactiae 2603V/R 1013155 NP_687396.1 CDS SAG0362 NC_004116.1 374015 374827 R identified by match to PFAM protein family HMM PF00702; HAD superfamily hydrolase complement(374015..374827) Streptococcus agalactiae 2603V/R 1013156 NP_687397.1 CDS SAG0363 NC_004116.1 374916 375500 D hypothetical protein 374916..375500 Streptococcus agalactiae 2603V/R 1013157 NP_687398.1 CDS SAG0364 NC_004116.1 375590 376201 D similar to GB:AE000520; identified by sequence similarity; hypothetical protein 375590..376201 Streptococcus agalactiae 2603V/R 1013158 NP_687399.1 CDS SAG0365 NC_004116.1 376304 377725 D identified by match to PFAM protein family HMM PF00860; xanthine/uracil permease family protein 376304..377725 Streptococcus agalactiae 2603V/R 1013159 NP_687400.1 CDS SAG0366 NC_004116.1 377808 378317 D hypothetical protein 377808..378317 Streptococcus agalactiae 2603V/R 1013160 NP_687401.1 CDS SAG0367 NC_004116.1 378271 378831 D identified by match to PFAM protein family HMM PF00583; acetyltransferase 378271..378831 Streptococcus agalactiae 2603V/R 1013161 NP_687402.1 CDS SAG0368 NC_004116.1 378840 380147 D identified by match to TIGR protein family HMM TIGR00350; The product of this gene was detected by Western blot analysis. For details on the method see Tettelin et al. 2002.; hypothetical protein 378840..380147 Streptococcus agalactiae 2603V/R 1013162 NP_687403.1 CDS SAG0369 NC_004116.1 380211 380507 R hypothetical protein complement(380211..380507) Streptococcus agalactiae 2603V/R 1013163 NP_687404.1 CDS hit NC_004116.1 380504 380923 R identified by match to PFAM protein family HMM PF01230; HIT family protein complement(380504..380923) Streptococcus agalactiae 2603V/R 1013164 NP_687405.1 CDS SAG0371 NC_004116.1 381259 381762 D hypothetical protein 381259..381762 Streptococcus agalactiae 2603V/R 1013165 NP_687406.1 CDS SAG0372 NC_004116.1 381814 382071 R hypothetical protein complement(381814..382071) Streptococcus agalactiae 2603V/R 1013166 NP_687407.1 CDS SAG0373 NC_004116.1 382071 382796 D identified by match to PFAM protein family HMM PF00005; ABC transporter ATP-binding protein 382071..382796 Streptococcus agalactiae 2603V/R 1013167 NP_687408.1 CDS SAG0374 NC_004116.1 382798 383832 D similar to OMNI:NTL01SPL1360; identified by sequence similarity; ABC transporter permease 382798..383832 Streptococcus agalactiae 2603V/R 1013168 NP_687409.1 CDS SAG0375 NC_004116.1 383890 384690 D hypothetical protein 383890..384690 Streptococcus agalactiae 2603V/R 1013169 NP_687410.1 CDS trmB NC_004116.1 384680 385315 D tRNA (guanine-N(7)-)-methyltransferase; catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA by transferring the methyl residue from S-adenosyl-L-methionine; tRNA (guanine-N(7)-)-methyltransferase 384680..385315 Streptococcus agalactiae 2603V/R 1013170 NP_687411.1 CDS SAG0377 NC_004116.1 385898 386281 D in Streptococcus pneumoniae this gene was found to be essential; structure determination of the Streptococcus protein shows that it is similar to a number of other proteins; hypothetical protein 385898..386281 Streptococcus agalactiae 2603V/R 1013172 NP_687412.2 CDS nusA NC_004116.1 386317 387468 D modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination; transcription elongation factor NusA 386317..387468 Streptococcus agalactiae 2603V/R 1013173 NP_687413.1 CDS SAG0379 NC_004116.1 387490 387786 D hypothetical protein 387490..387786 Streptococcus agalactiae 2603V/R 1013174 NP_687414.1 CDS SAG0380 NC_004116.1 387779 388081 D identified by match to PFAM protein family HMM PF01248; hypothetical protein 387779..388081 Streptococcus agalactiae 2603V/R 1013175 NP_687415.1 CDS infB NC_004116.1 388101 390884 D Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; translation initiation factor IF-2 388101..390884 Streptococcus agalactiae 2603V/R 1013176 NP_687416.1 CDS rbfA NC_004116.1 390975 391343 D associates with free 30S ribosomal subunits; essential for efficient processing of 16S rRNA; in Escherichia coli rbfA is induced by cold shock; ribosome-binding factor A 390975..391343 Streptococcus agalactiae 2603V/R 1013177 NP_687417.1 CDS SAG0383 NC_004116.1 391427 392431 R similar to OMNI:NTL01SPL1351; identified by sequence similarity; The product of this gene was detected by Western blot analysis. For details on the method see Tettelin et al. 2002.; hypothetical protein complement(391427..392431) Streptococcus agalactiae 2603V/R 1013178 NP_687418.1 CDS SAG0384 NC_004116.1 392595 393011 D transcriptional repressor CopY 392595..393011 Streptococcus agalactiae 2603V/R 1013179 NP_687419.1 CDS SAG0385 NC_004116.1 393024 395258 D identified by match to PFAM protein family HMM PF00122; copper-transporter ATPase CopA 393024..395258 Streptococcus agalactiae 2603V/R 1013180 NP_687420.1 CDS SAG0386 NC_004116.1 395299 395505 D identified by match to PFAM protein family HMM PF00403; copper-transporter protein CopZ 395299..395505 Streptococcus agalactiae 2603V/R 1013181 NP_687421.1 CDS SAG0387 NC_004116.1 395615 396229 D identified by match to PFAM protein family HMM PF03458; hypothetical protein 395615..396229 Streptococcus agalactiae 2603V/R 1013182 NP_687422.1 CDS SAG0388 NC_004116.1 396244 397056 D identified by match to PFAM protein family HMM PF00702; HAD superfamily hydrolase 396244..397056 Streptococcus agalactiae 2603V/R 1013183 NP_687423.1 CDS polA NC_004116.1 397169 399811 D has 3'-5' exonuclease, 5'-3' exonuclease and 5'-3'polymerase activities, primarily functions to fill gaps during DNA replication and repair; DNA polymerase I 397169..399811 Streptococcus agalactiae 2603V/R 1013184 NP_687424.1 CDS SAG0390 NC_004116.1 399841 400281 D identified by match to PFAM protein family HMM PF02629; CoA-binding domain-containing protein 399841..400281 Streptococcus agalactiae 2603V/R 1013185 NP_687425.1 CDS SAG0391 NC_004116.1 400363 400842 D identified by match to PFAM protein family HMM PF01475; FUR family transcriptional regulator 400363..400842 Streptococcus agalactiae 2603V/R 1013186 NP_687426.1 CDS SAG0392 NC_004116.1 400995 402560 D identified by match to PFAM protein family HMM PF00746; The product of this gene was detected by Western blot analysis. For details on the method see Tettelin et al. 2002.; cell wall surface anchor family protein 400995..402560 Streptococcus agalactiae 2603V/R 1013187 NP_687427.1 CDS SAG0393 NC_004116.1 402673 403359 D identified by match to PFAM protein family HMM PF00072; DNA-binding response regulator 402673..403359 Streptococcus agalactiae 2603V/R 1013188 NP_687428.1 CDS SAG0394 NC_004116.1 403361 404398 D identified by match to PFAM protein family HMM PF00512; sensor histidine kinase 403361..404398 Streptococcus agalactiae 2603V/R 1013189 NP_687429.1 CDS SAG0395 NC_004116.1 404412 405152 R similar to OMNI:NTL01SPL0158; identified by sequence similarity; hypothetical protein complement(404412..405152) Streptococcus agalactiae 2603V/R 1013190 NP_687430.1 CDS tgt NC_004116.1 405339 406481 D Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr); queuine tRNA-ribosyltransferase 405339..406481 Streptococcus agalactiae 2603V/R 1013191 NP_687431.1 CDS SAG0397 NC_004116.1 406591 406899 D hypothetical protein 406591..406899 Streptococcus agalactiae 2603V/R 1013192 NP_687432.1 CDS SAG0398 NC_004116.1 406906 407445 D identified by match to PFAM protein family HMM PF02632; BioY family protein 406906..407445 Streptococcus agalactiae 2603V/R 1013193 NP_687433.1 CDS SAG0399 NC_004116.1 407584 408360 D AtsA/ElaC family protein 407584..408360 Streptococcus agalactiae 2603V/R 1013194 NP_687434.1 CDS SAG0400 NC_004116.1 408360 408866 D identified by match to PFAM protein family HMM PF00383; cytidine/deoxycytidylate deaminase family protein 408360..408866 Streptococcus agalactiae 2603V/R 1013195 NP_687435.1 CDS SAG0401 NC_004116.1 408968 409102 D hypothetical protein 408968..409102 Streptococcus agalactiae 2603V/R 1013196 NP_687436.1 CDS pgi NC_004116.1 409138 410487 D functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis; catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate; member of PGI family; glucose-6-phosphate isomerase 409138..410487 Streptococcus agalactiae 2603V/R 1013197 NP_687437.1 CDS SAG0403 NC_004116.1 410809 411336 D identified by match to PFAM protein family HMM PF01812; 5-formyltetrahydrofolate cyclo-ligase 410809..411336 Streptococcus agalactiae 2603V/R 1013198 NP_687438.1 CDS SAG0404 NC_004116.1 411327 412004 D identified by match to PFAM protein family HMM PF01694; rhomboid family protein 411327..412004 Streptococcus agalactiae 2603V/R 1013199 NP_687439.1 CDS SAG0405 NC_004116.1 412136 413179 D identified by match to PFAM protein family HMM PF02608; The product of this gene was detected by Western blot analysis. For details on the method see Tettelin et al. 2002.; hypothetical protein 412136..413179 Streptococcus agalactiae 2603V/R 1013200 NP_687440.1 CDS galU NC_004116.1 413270 414169 R identified by match to PFAM protein family HMM PF00483; UTP-glucose-1-phosphate uridylyltransferase complement(413270..414169) Streptococcus agalactiae 2603V/R 1013201 NP_687441.1 CDS gpsA NC_004116.1 414206 415222 R catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate; NAD(P)H-dependent glycerol-3-phosphate dehydrogenase complement(414206..415222) Streptococcus agalactiae 2603V/R 1013202 NP_687442.1 CDS rnpA NC_004116.1 415392 415721 D protein component of RNaseP which catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'terminus; this enzyme also cleaves other RNA substrates; ribonuclease P 415392..415721 Streptococcus agalactiae 2603V/R 1013203 NP_687443.1 CDS SAG0409 NC_004116.1 415734 416549 D identified by match to PFAM protein family HMM PF02096; SpoIIIJ family protein 415734..416549 Streptococcus agalactiae 2603V/R 1013204 NP_687444.1 CDS SAG0410 NC_004116.1 416557 417378 D identified by match to PFAM protein family HMM PF01424; R3H domain-containing protein 416557..417378 Streptococcus agalactiae 2603V/R 1013205 NP_687445.1 CDS SAG0411 NC_004116.1 423100 423633 R hypothetical protein complement(423100..423633) Streptococcus agalactiae 2603V/R 1013213 NP_687446.1 CDS recX NC_004116.1 423717 424493 R binds RecA and inhibits RecA-mediated DNA strand exchange and ATP hydrolysis and coprotease activities; RecX family transcriptional regulator complement(423717..424493) Streptococcus agalactiae 2603V/R 1013214 NP_687447.1 CDS SAG0413 NC_004116.1 424592 425947 D identified by match to PFAM protein family HMM PF01938; RNA methyltransferase 424592..425947 Streptococcus agalactiae 2603V/R 1013215 NP_687448.1 CDS SAG0414 NC_004116.1 426216 426677 D hypothetical protein 426216..426677 Streptococcus agalactiae 2603V/R 1013216 NP_687449.1 CDS SAG0415 NC_004116.1 426820 427248 D identified by match to PFAM protein family HMM PF00583; acetyltransferase 426820..427248 Streptococcus agalactiae 2603V/R 1013217 NP_687450.1 CDS SAG0416 NC_004116.1 427436 431137 D identified by match to PFAM protein family HMM PF00082; The product of this gene was detected by Western blot analysis. For details on the method see Tettelin et al. 2002.; protease 427436..431137 Streptococcus agalactiae 2603V/R 1013218 NP_687451.1 CDS SAG0417 NC_004116.1 431347 432255 D identified by match to PFAM protein family HMM PF00535; glycosyl transferase family protein 431347..432255 Streptococcus agalactiae 2603V/R 1013219 NP_687452.1 CDS nrdF NC_004116.1 432807 433817 D B2 or R2 protein; type 1b enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdE; ribonucleotide-diphosphate reductase subunit beta 432807..433817 Streptococcus agalactiae 2603V/R 1013220 NP_687453.1 CDS nrdI NC_004116.1 433818 434231 D in Salmonella NrdI has a stimulatory effect on the ribonucleotide reductase activity of NrdH with NrdEF; ribonucleotide reductase stimulatory protein 433818..434231 Streptococcus agalactiae 2603V/R 1013221 NP_687454.1 CDS nrdE-1 NC_004116.1 434233 436398 D Catalyzes the rate-limiting step in dNTP synthesis; ribonucleotide-diphosphate reductase subunit alpha 434233..436398 Streptococcus agalactiae 2603V/R 1013222 NP_687455.1 CDS SAG0421 NC_004116.1 436461 439628 D similar to OMNI:NTL01SPL0643; identified by sequence similarity; There are documented cases with S in place of G in the LPXTG motif. The product of this gene was detected by Western blot analysis. For details on the method see Tettelin et al. 2002.; hypothetical protein 436461..439628 Streptococcus agalactiae 2603V/R 1013223 NP_687456.1 CDS SAG0422 NC_004116.1 439641 440030 D hypothetical protein 439641..440030 Streptococcus agalactiae 2603V/R 1013224 NP_687457.1 CDS SAG0423 NC_004116.1 440074 440472 R similar to OMNI:NTL01CA0427; identified by sequence similarity; hypothetical protein complement(440074..440472) Streptococcus agalactiae 2603V/R 1013225 NP_687458.1 CDS SAG0424 NC_004116.1 440744 441028 R hypothetical protein complement(440744..441028) Streptococcus agalactiae 2603V/R 1013226 NP_687459.1 CDS SAG0425 NC_004116.1 441115 441432 R identified by match to PFAM protein family HMM PF02627; carboxymuconolactone decarboxylase family protein complement(441115..441432) Streptococcus agalactiae 2603V/R 1013227 NP_687460.1 CDS SAG0426 NC_004116.1 441456 441851 R hypothetical protein complement(441456..441851) Streptococcus agalactiae 2603V/R 1013228 NP_687461.1 CDS SAG0427 NC_004116.1 441861 442250 R identified by match to PFAM protein family HMM PF00376; MerR family transcriptional regulator complement(441861..442250) Streptococcus agalactiae 2603V/R 1013229 NP_687462.1 CDS SAG0428 NC_004116.1 442266 443303 R identified by match to PFAM protein family HMM PF00107; zinc-containing alcohol dehydrogenase complement(442266..443303) Streptococcus agalactiae 2603V/R 1013230 NP_687463.1 CDS SAG0429 NC_004116.1 443413 444267 R identified by match to PFAM protein family HMM PF00248; aldo/keto reductase complement(443413..444267) Streptococcus agalactiae 2603V/R 1013231 NP_687464.1 CDS SAG0430 NC_004116.1 444352 445215 R identified by match to PFAM protein family HMM PF01545; cation efflux system protein complement(444352..445215) Streptococcus agalactiae 2603V/R 1013232 NP_687465.1 CDS SAG0431 NC_004116.1 445347 445871 D identified by match to PFAM protein family HMM PF00440; TetR family transcriptional regulator 445347..445871 Streptococcus agalactiae 2603V/R 1013233 NP_687466.1 CDS SAG0432 NC_004116.1 446066 447259 R identified by match to PFAM protein family HMM PF00165; AraC family transcriptional regulator complement(446066..447259) Streptococcus agalactiae 2603V/R 1013234 NP_687467.1 CDS SAG0433 NC_004116.1 447507 451676 D identified by match to PFAM protein family HMM PF00746; surface protein Rib 447507..451676 Streptococcus agalactiae 2603V/R 1013235 NP_687468.1 CDS SAG0435 NC_004116.1 452388 452681 D similar to PID:984582 GB:U00096 SP:Q47150 PID:1786420; identified by sequence similarity; DNA-damage-inducible protein J 452388..452681 Streptococcus agalactiae 2603V/R 1013237 NP_687469.1 CDS SAG0436 NC_004116.1 452678 452866 D hypothetical protein 452678..452866 Streptococcus agalactiae 2603V/R 1013238 NP_687470.1 CDS SAG0437 NC_004116.1 453019 453390 D lipoprotein 453019..453390 Streptococcus agalactiae 2603V/R 1013239 NP_687471.1 CDS SAG0440 NC_004116.1 455763 456017 D hypothetical protein 455763..456017 Streptococcus agalactiae 2603V/R 1013243 NP_687472.1 CDS SAG0441 NC_004116.1 456126 456437 D similar to GP:13622655; identified by sequence similarity; hypothetical protein 456126..456437 Streptococcus agalactiae 2603V/R 1013244 NP_687473.1 CDS SAG0442 NC_004116.1 456705 457274 D identified by match to PFAM protein family HMM PF00583; acetyltransferase 456705..457274 Streptococcus agalactiae 2603V/R 1013245 NP_687474.1 CDS SAG0443 NC_004116.1 457372 457956 D identified by match to PFAM protein family HMM PF00583; acetyltransferase 457372..457956 Streptococcus agalactiae 2603V/R 1013246 NP_687475.1 CDS SAG0444 NC_004116.1 457953 458519 D hypothetical protein 457953..458519 Streptococcus agalactiae 2603V/R 1013247 NP_687476.1 CDS valS NC_004116.1 458519 461170 D valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain; valyl-tRNA synthetase 458519..461170 Streptococcus agalactiae 2603V/R 1013248 NP_687477.1 CDS SAG0446 NC_004116.1 461341 462300 D identified by match to PFAM protein family HMM PF01408; Gfo/Idh/MocA family oxidoreductase 461341..462300 Streptococcus agalactiae 2603V/R 1013249 NP_687478.1 CDS SAG0447 NC_004116.1 462461 463324 D identified by match to PFAM protein family HMM PF01544; magnesium transporter CorA family protein 462461..463324 Streptococcus agalactiae 2603V/R 1013250 NP_687479.1 CDS SAG0448 NC_004116.1 463371 464546 R identified by match to PFAM protein family HMM PF00872; IS256 family transposase complement(463371..464546) Streptococcus agalactiae 2603V/R 1013251 NP_687480.1 CDS SAG0449 NC_004116.1 464852 465916 D hypothetical protein 464852..465916 Streptococcus agalactiae 2603V/R 1013252 NP_687481.1 CDS asnA NC_004116.1 466030 467022 D catalyzes the formation of asparagine from aspartate and ammonia; asparagine synthetase AsnA 466030..467022 Streptococcus agalactiae 2603V/R 1013253 NP_687482.1 CDS SAG0451 NC_004116.1 467067 467516 R hypothetical protein complement(467067..467516) Streptococcus agalactiae 2603V/R 1013254 NP_687483.1 CDS SAG0452 NC_004116.1 467646 468185 D identified by match to TIGR protein family HMM TIGR00095; type II DNA modification methyltransferase 467646..468185 Streptococcus agalactiae 2603V/R 1013255 NP_687484.1 CDS SAG0453 NC_004116.1 468197 468487 D hypothetical protein 468197..468487 Streptococcus agalactiae 2603V/R 1013256 NP_687485.1 CDS coaD NC_004116.1 468484 468969 D Catalyzes the conversion of ATP and pantetheine 4'-phosphate to diphosphate and 3'-dephospho-coA; phosphopantetheine adenylyltransferase 468484..468969 Streptococcus agalactiae 2603V/R 1013257 NP_687486.1 CDS SAG0455 NC_004116.1 468959 470032 D hypothetical protein 468959..470032 Streptococcus agalactiae 2603V/R 1013258 NP_687487.1 CDS SAG0457 NC_004116.1 471508 472086 D hypothetical protein 471508..472086 Streptococcus agalactiae 2603V/R 1013260 NP_687488.1 CDS SAG0458 NC_004116.1 472137 473243 D 23S rRNA m2A2503 methyltransferase; methylates the C2 position of the A2530 nucleotide in 23S rRNA; may be involved in antibiotic resistance; ribosomal RNA large subunit methyltransferase N 472137..473243 Streptococcus agalactiae 2603V/R 1013261 NP_687489.1 CDS SAG0459 NC_004116.1 473243 473758 D similar to OMNI:SP0769; identified by sequence similarity; VanZF domain-containing protein 473243..473758 Streptococcus agalactiae 2603V/R 1013262 NP_687490.1 CDS SAG0460 NC_004116.1 473937 475682 D identified by match to PFAM protein family HMM PF00005; ABC transporter ATP-binding protein/permease 473937..475682 Streptococcus agalactiae 2603V/R 1013263 NP_687491.1 CDS SAG0461 NC_004116.1 475672 477411 D identified by match to PFAM protein family HMM PF00005; ABC transporter ATP-binding protein/permease 475672..477411 Streptococcus agalactiae 2603V/R 1013264 NP_687492.1 CDS trpG NC_004116.1 477539 478105 D TrpG; with TrpE catalyzes the formation of anthranilate and glutamate from chorismate and glutamine; TrpG provides the glutamine amidotransferase activity; anthranilate synthase component II 477539..478105 Streptococcus agalactiae 2603V/R 1013265 NP_687493.1 CDS SAG0463 NC_004116.1 478172 478711 R identified by match to PFAM protein family HMM PF02632; BioY family protein complement(478172..478711) Streptococcus agalactiae 2603V/R 1013266 NP_687494.1 CDS bioB NC_004116.1 478712 479704 R identified by match to PFAM protein family HMM PF01792; biotin synthetase complement(478712..479704) Streptococcus agalactiae 2603V/R 1013267 NP_687495.1 CDS SAG0465 NC_004116.1 479828 480322 D hypothetical protein 479828..480322 Streptococcus agalactiae 2603V/R 1013268 NP_687496.1 CDS SAG0466 NC_004116.1 480332 481447 D identified by match to PFAM protein family HMM PF00108; thiolase 480332..481447 Streptococcus agalactiae 2603V/R 1013269 NP_687497.1 CDS SAG0467 NC_004116.1 481440 482669 D AMP-binding protein 481440..482669 Streptococcus agalactiae 2603V/R 1013270 NP_687498.1 CDS nth NC_004116.1 482782 483414 D identified by match to PFAM protein family HMM PF00730; endonuclease III 482782..483414 Streptococcus agalactiae 2603V/R 1013271 NP_687499.1 CDS SAG0469 NC_004116.1 483415 483810 R similar to OMNI:SP1808; identified by sequence similarity; type IV prepilin peptidase-like protein complement(483415..483810) Streptococcus agalactiae 2603V/R 1013272 NP_687500.1 CDS SAG0470 NC_004116.1 483965 484174 D hypothetical protein 483965..484174 Streptococcus agalactiae 2603V/R 1013273 NP_687501.1 CDS glk NC_004116.1 484171 485139 D identified by match to PFAM protein family HMM PF00480; glucokinase 484171..485139 Streptococcus agalactiae 2603V/R 1013274 NP_687502.1 CDS SAG0472 NC_004116.1 485151 485531 D identified by match to PFAM protein family HMM PF00581; The product of this gene was detected by Western blot analysis. For details on the method see Tettelin et al. 2002.; rhodanese-like domain-containing protein 485151..485531 Streptococcus agalactiae 2603V/R 1013275 NP_687503.1 CDS SAG0473 NC_004116.1 485763 487604 D identified by match to PFAM protein family HMM PF00009; elongation factor Tu family protein 485763..487604 Streptococcus agalactiae 2603V/R 1013276 NP_687504.1 CDS SAG0474 NC_004116.1 487649 487894 D hypothetical protein 487649..487894 Streptococcus agalactiae 2603V/R 1013277 NP_687505.1 CDS murD NC_004116.1 488024 489379 D UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase 488024..489379 Streptococcus agalactiae 2603V/R 1013278 NP_687506.1 CDS murG NC_004116.1 489382 490458 D UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; involved in cell wall formation; inner membrane-associated; last step of peptidoglycan synthesis; undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase 489382..490458 Streptococcus agalactiae 2603V/R 1013279 NP_687507.1 CDS SAG0477 NC_004116.1 490462 491598 D similar to OMNI:SP0690; identified by sequence similarity; cell division protein DivIB 490462..491598 Streptococcus agalactiae 2603V/R 1013280 NP_687508.1 CDS ftsA NC_004116.1 491954 493243 D identified by match to PFAM protein family HMM PF02491; cell division protein FtsA 491954..493243 Streptococcus agalactiae 2603V/R 1013281 NP_687509.1 CDS ftsZ NC_004116.1 493265 494545 D GTPase; similar structure to tubulin; forms ring-shaped polymers at the site of cell division; other proteins such as FtsA, ZipA, and ZapA, interact with and regulate FtsZ function; cell division protein FtsZ 493265..494545 Streptococcus agalactiae 2603V/R 1013282 NP_687510.1 CDS SAG0480 NC_004116.1 494551 495225 D identified by match to PFAM protein family HMM PF01168; hypothetical protein 494551..495225 Streptococcus agalactiae 2603V/R 1013283 NP_687511.1 CDS ylmF NC_004116.1 495237 495842 D similar to GP:4009494; identified by sequence similarity; hypothetical protein 495237..495842 Streptococcus agalactiae 2603V/R 1013284 NP_687512.1 CDS SAG0482 NC_004116.1 495845 496099 D identified by match to PFAM protein family HMM PF02325; hypothetical protein 495845..496099 Streptococcus agalactiae 2603V/R 1013285 NP_687513.1 CDS ylmH NC_004116.1 496101 496889 D identified by match to PFAM protein family HMM PF01479; hypothetical protein 496101..496889 Streptococcus agalactiae 2603V/R 1013286 NP_687514.1 CDS SAG0484 NC_004116.1 496899 497669 D similar to OMNI:SP1661; identified by sequence similarity; cell division protein DivIVA 496899..497669 Streptococcus agalactiae 2603V/R 1013287 NP_687515.1 CDS ileS NC_004116.1 497954 500746 D IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase family; some organisms carry two different copies of this enzyme; isoleucyl-tRNA synthetase 497954..500746 Streptococcus agalactiae 2603V/R 1013288 NP_687516.1 CDS SAG0486 NC_004116.1 500863 501165 R hypothetical protein complement(500863..501165) Streptococcus agalactiae 2603V/R 1013289 NP_687517.1 CDS SAG0487 NC_004116.1 501229 501684 R identified by match to PFAM protein family HMM PF00293; MutT/nudix family protein complement(501229..501684) Streptococcus agalactiae 2603V/R 1013290 NP_687518.1 CDS SAG0488 NC_004116.1 501870 504131 R identified by match to PFAM protein family HMM PF00004; ATP-dependent Clp protease, ATP-binding subunit complement(501870..504131) Streptococcus agalactiae 2603V/R 1013291 NP_687519.1 CDS SAG0489 NC_004116.1 504287 504391 D hypothetical protein 504287..504391 Streptococcus agalactiae 2603V/R 1013292 NP_687520.1 CDS SAG0490 NC_004116.1 504429 504659 D hypothetical protein 504429..504659 Streptococcus agalactiae 2603V/R 1013293 NP_687521.1 CDS SAG0491 NC_004116.1 504801 505493 D identified by match to PFAM protein family HMM PF00528; amino acid ABC transporter permease 504801..505493 Streptococcus agalactiae 2603V/R 1013294 NP_687522.1 CDS SAG0492 NC_004116.1 505486 506220 D identified by match to PFAM protein family HMM PF00005; amino acid ABC transporter ATP-binding protein 505486..506220 Streptococcus agalactiae 2603V/R 1013295 NP_687523.1 CDS SAG0493 NC_004116.1 506507 508201 D identified by match to PFAM protein family HMM PF00408; phosphoglucomutase/phosphomannomutase family protein 506507..508201 Streptococcus agalactiae 2603V/R 1013296 NP_687524.1 CDS folD NC_004116.1 508340 509194 D catalyzes the formation of 5,10-methenyltetrahydrofolate from 5,10-methylenetetrahydrofolate and subsequent formation of 10-formyltetrahydrofolate from 5,10-methenyltetrahydrofolate; bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase 508340..509194 Streptococcus agalactiae 2603V/R 1013297 NP_687525.1 CDS SAG0495 NC_004116.1 509191 510027 D identified by match to PFAM protein family HMM PF01256; The product of this gene was detected by Western blot analysis. For details on the method see Tettelin et al. 2002.; hypothetical protein 509191..510027 Streptococcus agalactiae 2603V/R 1013298 NP_687526.1 CDS xseA NC_004116.1 510153 511493 D bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides; exodeoxyribonuclease VII large subunit 510153..511493 Streptococcus agalactiae 2603V/R 1013299 NP_687527.1 CDS xseB NC_004116.1 511471 511686 D catalyzes the bidirectional exonucleolytic cleavage of DNA; exodeoxyribonuclease VII small subunit 511471..511686 Streptococcus agalactiae 2603V/R 1013300 NP_687528.1 CDS SAG0498 NC_004116.1 511686 512558 D identified by match to PFAM protein family HMM PF00348; geranyltranstransferase 511686..512558 Streptococcus agalactiae 2603V/R 1013301 NP_687529.1 CDS SAG0499 NC_004116.1 512551 513378 D identified by match to PFAM protein family HMM PF01479; hemolysin A 512551..513378 Streptococcus agalactiae 2603V/R 1013302 NP_687530.1 CDS SAG0500 NC_004116.1 513365 513838 D identified by match to PFAM protein family HMM PF01316; arginine repressor ArgR 513365..513838 Streptococcus agalactiae 2603V/R 1013303 NP_687531.1 CDS recN NC_004116.1 513850 515508 D identified by match to PFAM protein family HMM PF02463; DNA repair protein RecN 513850..515508 Streptococcus agalactiae 2603V/R 1013304 NP_687532.1 CDS SAG0502 NC_004116.1 515621 516457 D identified by match to PFAM protein family HMM PF02645; The product of this gene was detected by Western blot analysis. For details on the method see Tettelin et al. 2002.; DegV family protein 515621..516457 Streptococcus agalactiae 2603V/R 1013305 NP_687533.1 CDS SAG0503 NC_004116.1 516450 517289 D identified by match to PFAM protein family HMM PF00657; The product of this gene was detected by Western blot analysis. For details on the method see Tettelin et al. 2002.; lipase/acylhydrolase 516450..517289 Streptococcus agalactiae 2603V/R 1013306 NP_687534.1 CDS SAG0504 NC_004116.1 517264 517866 D hypothetical protein 517264..517866 Streptococcus agalactiae 2603V/R 1013307 NP_687535.1 CDS hup NC_004116.1 517969 518244 D identified by match to PFAM protein family HMM PF00216; DNA-binding protein HU 517969..518244 Streptococcus agalactiae 2603V/R 1013308 NP_687536.1 CDS SAG0506 NC_004116.1 518441 518638 D hypothetical protein 518441..518638 Streptococcus agalactiae 2603V/R 1013309 NP_687537.1 CDS pyrDA NC_004116.1 518682 519614 R catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway; subclass 1A is a dimer formed by two identical PyrD subunits each containing an FMN group; dihydroorotate dehydrogenase 1A complement(518682..519614) Streptococcus agalactiae 2603V/R 1013310 NP_687538.1 CDS fibB NC_004116.1 519801 521036 R identified by match to PFAM protein family HMM PF02388; beta-lactam resistance factor complement(519801..521036) Streptococcus agalactiae 2603V/R 1013311 NP_687539.1 CDS fibA NC_004116.1 521055 522266 R identified by match to PFAM protein family HMM PF02388; beta-lactam resistance factor complement(521055..522266) Streptococcus agalactiae 2603V/R 1013312 NP_687540.1 CDS SAG0510 NC_004116.1 522279 523499 R identified by match to PFAM protein family HMM PF02388; MurM protein complement(522279..523499) Streptococcus agalactiae 2603V/R 1013313 NP_687541.1 CDS SAG0511 NC_004116.1 523499 524311 R identified by match to PFAM protein family HMM PF00702; HAD superfamily hydrolase complement(523499..524311) Streptococcus agalactiae 2603V/R 1013314 NP_687542.1 CDS SAG0512 NC_004116.1 524382 525698 R identified by match to PFAM protein family HMM PF01966; HD domain-containing protein complement(524382..525698) Streptococcus agalactiae 2603V/R 1013315 NP_687543.1 CDS SAG0513 NC_004116.1 525774 526160 D hypothetical protein 525774..526160 Streptococcus agalactiae 2603V/R 1013316 NP_687544.1 CDS SAG0514 NC_004116.1 526504 529188 D identified by match to PFAM protein family HMM PF00122; cation transporter E1-E2 family ATPase 526504..529188 Streptococcus agalactiae 2603V/R 1013317 NP_687545.1 CDS SAG0515 NC_004116.1 529233 530093 R hypothetical protein complement(529233..530093) Streptococcus agalactiae 2603V/R 1013318 NP_687546.1 CDS SAG0516 NC_004116.1 530245 532176 D similar to PID:1064791 GB:AL009126; identified by sequence similarity; fructose-1,6-bisphosphatase 530245..532176 Streptococcus agalactiae 2603V/R 1013319 NP_687547.1 CDS SAG0517 NC_004116.1 532266 533390 D identified by match to PFAM protein family HMM PF00037; (Fe-S)-binding protein 532266..533390 Streptococcus agalactiae 2603V/R 1013320 NP_687548.1 CDS ftsE NC_004116.1 534576 535268 D identified by match to PFAM protein family HMM PF00005; cell division ABC transporter ATP-binding protein FtsE 534576..535268 Streptococcus agalactiae 2603V/R 1013322 NP_687549.1 CDS ftsX NC_004116.1 535252 536181 D identified by match to PFAM protein family HMM PF02687; cell division ABC transporter permease FtsX 535252..536181 Streptococcus agalactiae 2603V/R 1013323 NP_687550.1 CDS SAG0521 NC_004116.1 536234 536944 R similar to OMNI:EF0274; identified by sequence similarity; hypothetical protein complement(536234..536944) Streptococcus agalactiae 2603V/R 1013324 NP_687551.1 CDS SAG0522 NC_004116.1 536941 537639 R identified by match to PFAM protein family HMM PF00753; metallo-beta-lactamase superfamily protein complement(536941..537639) Streptococcus agalactiae 2603V/R 1013325 NP_687552.1 CDS SAG0523 NC_004116.1 537807 538571 D identified by match to PFAM protein family HMM PF00106; acetoin reductase 537807..538571 Streptococcus agalactiae 2603V/R 1013326 NP_687553.1 CDS SAG0524 NC_004116.1 538679 541186 D unwinds DNA; bifunctional ATP-dependent DNA helicase/DNA polymerase III subunit epsilon 538679..541186 Streptococcus agalactiae 2603V/R 1013327 NP_687554.1 CDS aspC NC_004116.1 541272 542465 D catalyzes the formation of oxalozcetate and L-glutamate from L-aspartate and 2-oxoglutarate; aspartate aminotransferase 541272..542465 Streptococcus agalactiae 2603V/R 1013328 NP_687555.1 CDS asnC NC_004116.1 542486 543832 D catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; asparaginyl-tRNA synthetase 542486..543832 Streptococcus agalactiae 2603V/R 1013329 NP_687556.1 CDS SAG0527 NC_004116.1 543872 544429 R hypothetical protein complement(543872..544429) Streptococcus agalactiae 2603V/R 1013330 NP_687557.1 CDS SAG0528 NC_004116.1 544426 545409 R identified by match to PFAM protein family HMM PF01156; inosine-uridine preferring nucleoside hydrolase complement(544426..545409) Streptococcus agalactiae 2603V/R 1013331 NP_687558.1 CDS SAG0529 NC_004116.1 545442 545558 R hypothetical protein complement(545442..545558) Streptococcus agalactiae 2603V/R 1013332 NP_687559.1 CDS SAG0530 NC_004116.1 545655 546068 R identified by match to PFAM protein family HMM PF02566; OsmC/Ohr family protein complement(545655..546068) Streptococcus agalactiae 2603V/R 1013333 NP_687560.1 CDS SAG0531 NC_004116.1 546222 547112 D hypothetical protein 546222..547112 Streptococcus agalactiae 2603V/R 1013334 NP_687561.1 CDS SAG0532 NC_004116.1 547109 548083 D hypothetical protein 547109..548083 Streptococcus agalactiae 2603V/R 1013335 NP_687562.1 CDS SAG0533 NC_004116.1 548080 548991 D hypothetical protein 548080..548991 Streptococcus agalactiae 2603V/R 1013336 NP_687563.1 CDS SAG0534 NC_004116.1 549006 550403 D similar to OMNI:NTL01LL1596; identified by sequence similarity; dipeptidase 549006..550403 Streptococcus agalactiae 2603V/R 1013337 NP_687564.1 CDS SAG0535 NC_004116.1 550545 552065 D identified by match to PFAM protein family HMM PF01297; zinc ABC transporter substrate-binding protein 550545..552065 Streptococcus agalactiae 2603V/R 1013338 NP_687565.1 CDS rpmE2 NC_004116.1 552178 552438 R RpmE2; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster do not have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome; 50S ribosomal protein L31 complement(552178..552438) Streptococcus agalactiae 2603V/R 1013339 NP_687566.1 CDS SAG0537 NC_004116.1 552547 553482 R identified by match to PFAM protein family HMM PF01368; DHH family protein complement(552547..553482) Streptococcus agalactiae 2603V/R 1013340 NP_687567.1 CDS SAG0538 NC_004116.1 553748 554770 D catalyzes the formation of inosine from adenosine; adenosine deaminase 553748..554770 Streptococcus agalactiae 2603V/R 1013341 NP_687568.1 CDS SAG0539 NC_004116.1 554829 555272 D An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group; flavodoxin 554829..555272 Streptococcus agalactiae 2603V/R 1013342 NP_687569.1 CDS SAG0540 NC_004116.1 555349 555624 D identified by match to PFAM protein family HMM PF01817; hypothetical protein 555349..555624 Streptococcus agalactiae 2603V/R 1013343 NP_687570.1 CDS SAG0541 NC_004116.1 555617 556813 D identified by match to PFAM protein family HMM PF00654; voltage-gated chloride channel family protein 555617..556813 Streptococcus agalactiae 2603V/R 1013344 NP_687571.1 CDS SAG0542 NC_004116.1 557266 557649 D similar to OMNI:SP0537; identified by sequence similarity; IS1381 transposase protein A 557266..557649 Streptococcus agalactiae 2603V/R 1013345 NP_687572.1 CDS SAG0543 NC_004116.1 557682 558071 D identified by match to PFAM protein family HMM PF01609; IS1381 transposase protein B 557682..558071 Streptococcus agalactiae 2603V/R 1013346 NP_687573.1 CDS rplS NC_004116.1 558254 558601 D this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site; 50S ribosomal protein L19 558254..558601 Streptococcus agalactiae 2603V/R 1013347 NP_687574.1 CDS SAG0545 NC_004116.1 558826 559905 R identified by match to PFAM protein family HMM PF00589; prophage LambdaSa1, site-specific recombinase phage integrase family protein complement(558826..559905) Streptococcus agalactiae 2603V/R 1013349 NP_687575.1 CDS SAG0546 NC_004116.1 560028 560231 R similar to GP:2444082; identified by sequence similarity; hypothetical protein complement(560028..560231) Streptococcus agalactiae 2603V/R 1013350 NP_687576.1 CDS SAG0547 NC_004116.1 560334 560891 R hypothetical protein complement(560334..560891) Streptococcus agalactiae 2603V/R 1013351 NP_687577.1 CDS SAG0548 NC_004116.1 560893 561690 R identified by match to PFAM protein family HMM PF00717; prophage LambdaSa1, repressor protein complement(560893..561690) Streptococcus agalactiae 2603V/R 1013352 NP_687578.1 CDS SAG0549 NC_004116.1 562051 562194 D hypothetical protein 562051..562194 Streptococcus agalactiae 2603V/R 1013353 NP_687579.1 CDS SAG0550 NC_004116.1 562191 562415 R hypothetical protein complement(562191..562415) Streptococcus agalactiae 2603V/R 1013354 NP_687580.1 CDS SAG0551 NC_004116.1 562474 562632 D hypothetical protein 562474..562632 Streptococcus agalactiae 2603V/R 1013355 NP_687581.1 CDS SAG0552 NC_004116.1 562662 562850 D hypothetical protein 562662..562850 Streptococcus agalactiae 2603V/R 1013356 NP_687582.1 CDS SAG0553 NC_004116.1 562833 563639 R hypothetical protein complement(562833..563639) Streptococcus agalactiae 2603V/R 1013357 NP_687583.1 CDS SAG0554 NC_004116.1 563691 563882 D identified by match to PFAM protein family HMM PF01381; prophage LambdaSa1, Cro/CI family transcriptional regulator 563691..563882 Streptococcus agalactiae 2603V/R 1013358 NP_687584.1 CDS SAG0555 NC_004116.1 563950 564699 D prophage LambdaSa1, antirepressor 563950..564699 Streptococcus agalactiae 2603V/R 1013359 NP_687585.1 CDS SAG0556 NC_004116.1 564711 564854 D hypothetical protein 564711..564854 Streptococcus agalactiae 2603V/R 1013360 NP_687586.1 CDS SAG0557 NC_004116.1 565004 565234 D hypothetical protein 565004..565234 Streptococcus agalactiae 2603V/R 1013361 NP_687587.1 CDS SAG0558 NC_004116.1 565372 565596 D hypothetical protein 565372..565596 Streptococcus agalactiae 2603V/R 1013362 NP_687588.1 CDS SAG0559 NC_004116.1 565607 566467 D hypothetical protein 565607..566467 Streptococcus agalactiae 2603V/R 1013363 NP_687589.1 CDS SAG0560 NC_004116.1 566448 566681 D hypothetical protein 566448..566681 Streptococcus agalactiae 2603V/R 1013364 NP_687590.1 CDS SAG0561 NC_004116.1 566678 566818 D hypothetical protein 566678..566818 Streptococcus agalactiae 2603V/R 1013365 NP_687591.1 CDS SAG0562 NC_004116.1 566829 567083 D hypothetical protein 566829..567083 Streptococcus agalactiae 2603V/R 1013366 NP_687592.1 CDS SAG0563 NC_004116.1 567086 567247 D hypothetical protein 567086..567247 Streptococcus agalactiae 2603V/R 1013367 NP_687593.1 CDS SAG0564 NC_004116.1 567249 567731 D hypothetical protein 567249..567731 Streptococcus agalactiae 2603V/R 1013368 NP_687594.1 CDS SAG0565 NC_004116.1 567732 568406 D similar to GP:8918764; identified by sequence similarity; hypothetical protein 567732..568406 Streptococcus agalactiae 2603V/R 1013369 NP_687595.1 CDS ssb-2 NC_004116.1 568399 568815 D identified by match to PFAM protein family HMM PF00436; prophage LambdaSa1, single-strand binding protein 568399..568815 Streptococcus agalactiae 2603V/R 1013370 NP_687596.1 CDS SAG0567 NC_004116.1 569396 570715 D identified by match to PFAM protein family HMM PF00078; prophage LambdaSa1, reverse transcriptase/maturase family protein 569396..570715 Streptococcus agalactiae 2603V/R 1013371 NP_687597.1 CDS SAG0568 NC_004116.1 570841 571044 D hypothetical protein 570841..571044 Streptococcus agalactiae 2603V/R 1013372 NP_687598.1 CDS SAG0569 NC_004116.1 571034 571510 D hypothetical protein 571034..571510 Streptococcus agalactiae 2603V/R 1013373 NP_687599.1 CDS SAG0570 NC_004116.1 571500 571847 D hypothetical protein 571500..571847 Streptococcus agalactiae 2603V/R 1013374 YP_008592386.1 CDS SAG_RS02245 NC_004116.1 571859 572161 D hypothetical protein 571859..572161 Streptococcus agalactiae 2603V/R 17097509 NP_687600.1 CDS SAG0571 NC_004116.1 572165 572296 D hypothetical protein 572165..572296 Streptococcus agalactiae 2603V/R 1013375 NP_687601.1 CDS SAG0572 NC_004116.1 572296 572712 D hypothetical protein 572296..572712 Streptococcus agalactiae 2603V/R 1013376 NP_687602.1 CDS SAG0573 NC_004116.1 572709 572873 D hypothetical protein 572709..572873 Streptococcus agalactiae 2603V/R 1013377 NP_687603.1 CDS SAG0574 NC_004116.1 572870 573139 D hypothetical protein 572870..573139 Streptococcus agalactiae 2603V/R 1013378 NP_687604.1 CDS SAG0575 NC_004116.1 573142 573474 D hypothetical protein 573142..573474 Streptococcus agalactiae 2603V/R 1013379 NP_687605.1 CDS SAG0576 NC_004116.1 573557 573688 D hypothetical protein 573557..573688 Streptococcus agalactiae 2603V/R 1013380 NP_687606.1 CDS SAG0577 NC_004116.1 573781 574314 D hypothetical protein 573781..574314 Streptococcus agalactiae 2603V/R 1013381 NP_687607.1 CDS SAG0578 NC_004116.1 574311 574577 D hypothetical protein 574311..574577 Streptococcus agalactiae 2603V/R 1013382 NP_687608.1 CDS SAG0579 NC_004116.1 574965 575393 D hypothetical protein 574965..575393 Streptococcus agalactiae 2603V/R 1013383 NP_687609.1 CDS SAG0581 NC_004116.1 576505 576861 D hypothetical protein 576505..576861 Streptococcus agalactiae 2603V/R 1013385 NP_687610.1 CDS SAG0582 NC_004116.1 576858 578126 D hypothetical protein 576858..578126 Streptococcus agalactiae 2603V/R 1013386 NP_687611.1 CDS SAG0583 NC_004116.1 578119 579339 D hypothetical protein 578119..579339 Streptococcus agalactiae 2603V/R 1013387 NP_687612.1 CDS SAG0585 NC_004116.1 579635 581050 D hypothetical protein 579635..581050 Streptococcus agalactiae 2603V/R 1013389 NP_687613.1 CDS SAG0586 NC_004116.1 581131 581595 D hypothetical protein 581131..581595 Streptococcus agalactiae 2603V/R 1013390 NP_687614.1 CDS SAG0587 NC_004116.1 581598 582500 D similar to PID:1353548; identified by sequence similarity; prophage LambdaSa1, structural protein 581598..582500 Streptococcus agalactiae 2603V/R 1013391 NP_687615.1 CDS SAG0588 NC_004116.1 582497 582712 D hypothetical protein 582497..582712 Streptococcus agalactiae 2603V/R 1013392 NP_687616.1 CDS SAG0589 NC_004116.1 582726 583157 D hypothetical protein 582726..583157 Streptococcus agalactiae 2603V/R 1013393 NP_687617.1 CDS SAG0590 NC_004116.1 583108 583446 D hypothetical protein 583108..583446 Streptococcus agalactiae 2603V/R 1013394 NP_687618.1 CDS SAG0591 NC_004116.1 583439 583675 D hypothetical protein 583439..583675 Streptococcus agalactiae 2603V/R 1013395 NP_687619.1 CDS SAG0592 NC_004116.1 583676 584011 D hypothetical protein 583676..584011 Streptococcus agalactiae 2603V/R 1013396 NP_687620.1 CDS SAG0593 NC_004116.1 584021 584578 D similar to PID:1353554; identified by sequence similarity; prophage LambdaSa1, structural protein 584021..584578 Streptococcus agalactiae 2603V/R 1013397 NP_687621.1 CDS SAG0594 NC_004116.1 584578 584823 D hypothetical protein 584578..584823 Streptococcus agalactiae 2603V/R 1013398 NP_687622.1 CDS SAG0595 NC_004116.1 584838 585209 D hypothetical protein 584838..585209 Streptococcus agalactiae 2603V/R 1013399 NP_687623.1 CDS SAG0596 NC_004116.1 585209 587221 D similar to GP:10732857; identified by sequence similarity; prophage LambdaSa1, pblA protein, internal deletion 585209..587221 Streptococcus agalactiae 2603V/R 1013400 NP_687624.1 CDS SAG0597 NC_004116.1 587215 588735 D similar to GP:3540285; identified by sequence similarity; prophage LambdaSa1, minor structural protein 587215..588735 Streptococcus agalactiae 2603V/R 1013401 NP_687625.1 CDS SAG0598 NC_004116.1 588736 592860 D identified by match to PFAM protein family HMM PF01832; prophage LambdaSa1, N-acetylmuramoyl-L-alanine amidase family protein 588736..592860 Streptococcus agalactiae 2603V/R 1013402 NP_687626.1 CDS SAG0599 NC_004116.1 592871 594877 D similar to GP:3540290; identified by sequence similarity; prophage LambdaSa1, minor structural protein 592871..594877 Streptococcus agalactiae 2603V/R 1013403 NP_687627.1 CDS SAG0600 NC_004116.1 594903 595232 D hypothetical protein 594903..595232 Streptococcus agalactiae 2603V/R 1013404 NP_687628.1 CDS SAG0601 NC_004116.1 595207 595419 D hypothetical protein 595207..595419 Streptococcus agalactiae 2603V/R 1013405 NP_687629.1 CDS SAG0602 NC_004116.1 595432 595734 D hypothetical protein 595432..595734 Streptococcus agalactiae 2603V/R 1013406 NP_687630.1 CDS SAG0603 NC_004116.1 595736 596071 D hypothetical protein 595736..596071 Streptococcus agalactiae 2603V/R 1013407 NP_687631.1 CDS SAG0604 NC_004116.1 596073 596792 D similar to GP:1934766; identified by sequence similarity; prophage LambdaSa1, lysin 596073..596792 Streptococcus agalactiae 2603V/R 1013408 NP_687632.1 CDS SAG0605 NC_004116.1 597125 598096 D hypothetical protein 597125..598096 Streptococcus agalactiae 2603V/R 1013409 NP_687633.1 CDS SAG0606 NC_004116.1 598200 598400 D hypothetical protein 598200..598400 Streptococcus agalactiae 2603V/R 1013410 NP_687634.1 CDS SAG0607 NC_004116.1 598441 598611 R hypothetical protein complement(598441..598611) Streptococcus agalactiae 2603V/R 1013411 NP_687635.1 CDS SAG0608 NC_004116.1 599028 599207 D hypothetical protein 599028..599207 Streptococcus agalactiae 2603V/R 1013412 NP_687636.1 CDS SAG0610 NC_004116.1 600190 600594 D hypothetical protein 600190..600594 Streptococcus agalactiae 2603V/R 1013414 NP_687637.1 CDS SAG0612 NC_004116.1 601746 601907 R hypothetical protein complement(601746..601907) Streptococcus agalactiae 2603V/R 1013416 NP_687638.1 CDS vex1 NC_004116.1 602649 603926 D identified by match to PFAM protein family HMM PF02687; transmembrane protein Vexp1 602649..603926 Streptococcus agalactiae 2603V/R 1013417 NP_687639.1 CDS vex2 NC_004116.1 603936 604592 D identified by match to PFAM protein family HMM PF00005; ABC transporter ATP-binding protein 603936..604592 Streptococcus agalactiae 2603V/R 1013418 NP_687640.1 CDS vex3 NC_004116.1 604592 605968 D identified by match to PFAM protein family HMM PF02687; transmembrane protein Vexp3 604592..605968 Streptococcus agalactiae 2603V/R 1013419 NP_687641.1 CDS vncR NC_004116.1 606065 606718 D identified by match to PFAM protein family HMM PF00072; DNA-binding response regulator VncR 606065..606718 Streptococcus agalactiae 2603V/R 1013420 NP_687642.1 CDS vncS NC_004116.1 606715 608034 D identified by match to PFAM protein family HMM PF00512; sensor histidine kinase VncS 606715..608034 Streptococcus agalactiae 2603V/R 1013421 NP_687643.1 CDS SAG0619 NC_004116.1 608911 609111 D hypothetical protein 608911..609111 Streptococcus agalactiae 2603V/R 1013423 NP_687644.1 CDS SAG0620 NC_004116.1 609153 609341 D hypothetical protein 609153..609341 Streptococcus agalactiae 2603V/R 1013424 NP_687645.1 CDS rodA NC_004116.1 609766 610971 D identified by match to PFAM protein family HMM PF01098; rod shape-determining protein RodA 609766..610971 Streptococcus agalactiae 2603V/R 1013425 NP_687646.1 CDS SAG0622 NC_004116.1 611090 611650 D identified by match to PFAM protein family HMM PF00702; HAD superfamily hydrolase 611090..611650 Streptococcus agalactiae 2603V/R 1013426 NP_687647.1 CDS gyrB NC_004116.1 611651 613603 D negatively supercoils closed circular double-stranded DNA; DNA gyrase subunit B 611651..613603 Streptococcus agalactiae 2603V/R 1013427 NP_687648.1 CDS SAG0624 NC_004116.1 613697 615421 D acts to negatively regulates ftsZ ring formation by modulating the frequency and position of the ftsZ ring formation; septation ring formation regulator EzrA 613697..615421 Streptococcus agalactiae 2603V/R 1013428 NP_687649.1 CDS serB NC_004116.1 615515 616156 D identified by match to PFAM protein family HMM PF00702; phosphoserine phosphatase SerB 615515..616156 Streptococcus agalactiae 2603V/R 1013429 NP_687650.1 CDS SAG0626 NC_004116.1 616177 616662 R identified by match to PFAM protein family HMM PF00293; MutT/nudix family protein complement(616177..616662) Streptococcus agalactiae 2603V/R 1013430 NP_687651.1 CDS SAG0627 NC_004116.1 616675 617130 R hypothetical protein complement(616675..617130) Streptococcus agalactiae 2603V/R 1013431 NP_687652.1 CDS eno NC_004116.1 617328 618635 D enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis; phosphopyruvate hydratase 617328..618635 Streptococcus agalactiae 2603V/R 1013432 NP_687653.1 CDS SAG0629 NC_004116.1 618743 619807 R similar to OMNI:NTL01SPL0534; identified by sequence similarity; hypothetical protein complement(618743..619807) Streptococcus agalactiae 2603V/R 1013433 NP_687654.1 CDS aroA NC_004116.1 620036 621319 D catalyzes the formation of 5-O-(1-carboxyvinyl)-3-phosphoshikimate from phosphoenolpyruvate and 3-phosphoshikimate in tryptophan biosynthesis; 3-phosphoshikimate 1-carboxyvinyltransferase 620036..621319 Streptococcus agalactiae 2603V/R 1013434 NP_687655.1 CDS aroK NC_004116.1 621312 621824 D catalyzes the formation of shikimate 3-phosphate from shikimate in aromatic amino acid biosynthesis; shikimate kinase 621312..621824 Streptococcus agalactiae 2603V/R 1013435 NP_687656.1 CDS SAG0632 NC_004116.1 621881 623254 D identified by match to TIGR protein family HMM TIGR00350; psr protein 621881..623254 Streptococcus agalactiae 2603V/R 1013436 NP_687657.1 CDS SAG0633 NC_004116.1 623355 624710 D identified by match to PFAM protein family HMM PF01938; RNA methyltransferase 623355..624710 Streptococcus agalactiae 2603V/R 1013437 NP_687658.1 CDS SAG0634 NC_004116.1 624827 625039 D hypothetical protein 624827..625039 Streptococcus agalactiae 2603V/R 1013438 NP_687659.1 CDS aphA NC_004116.1 625157 625894 D Class B; non-specific; catalyzes the dephosphorylation of organic phosphomonoesters; also has phosphotransferase activity; acid phosphatase/phosphotransferase 625157..625894 Streptococcus agalactiae 2603V/R 1013439 NP_687660.1 CDS SAG0636 NC_004116.1 626215 626733 D hypothetical protein 626215..626733 Streptococcus agalactiae 2603V/R 1013440 NP_687661.1 CDS SAG0639 NC_004116.1 628019 628840 R identified by match to PFAM protein family HMM PF00665; IS5 family transposase orfB complement(628019..628840) Streptococcus agalactiae 2603V/R 1013443 NP_687662.1 CDS SAG0640 NC_004116.1 628888 629163 R identified by match to PFAM protein family HMM PF01527; IS3 family transposase OrfA complement(628888..629163) Streptococcus agalactiae 2603V/R 1013444 NP_687663.1 CDS SAG0642 NC_004116.1 629519 629698 D hypothetical protein 629519..629698 Streptococcus agalactiae 2603V/R 1013446 NP_687664.1 CDS SAG0644 NC_004116.1 630361 631569 R identified by match to PFAM protein family HMM PF00165; AraC family transcriptional regulator complement(630361..631569) Streptococcus agalactiae 2603V/R 1013448 NP_687665.1 CDS SAG0645 NC_004116.1 631950 633614 D identified by match to PFAM protein family HMM PF00746; The product of this gene was detected by Western blot analysis. For details on the method see Tettelin et al. 2002.; cell wall surface anchor family protein 631950..633614 Streptococcus agalactiae 2603V/R 1013449 NP_687666.1 CDS SAG0646 NC_004116.1 633703 634626 D identified by match to TIGR protein family HMM TIGR01167; The product of this gene was detected by Western blot analysis. For details on the method see Tettelin et al. 2002.; cell wall surface anchor family protein 633703..634626 Streptococcus agalactiae 2603V/R 1013450 NP_687667.1 CDS SAG0647 NC_004116.1 634628 635545 D identified by match to TIGR protein family HMM TIGR01076; sortase family protein 634628..635545 Streptococcus agalactiae 2603V/R 1013451 NP_687668.1 CDS SAG0648 NC_004116.1 635571 636353 D identified by match to TIGR protein family HMM TIGR01076; sortase family protein 635571..636353 Streptococcus agalactiae 2603V/R 1013452 NP_687669.1 CDS SAG0649 NC_004116.1 636431 639103 D similar to OMNI:SP0462; identified by sequence similarity; The product of this gene was detected by Western blot analysis. For details on the method see Tettelin et al. 2002.; cell wall surface anchor family protein 636431..639103 Streptococcus agalactiae 2603V/R 1013453 NP_687670.1 CDS SAG0650 NC_004116.1 639378 639947 D identified by match to TIGR protein family HMM TIGR01076; sortase family protein 639378..639947 Streptococcus agalactiae 2603V/R 1013454 NP_687671.1 CDS SAG0651 NC_004116.1 640196 640801 D identified by Glimmer2; The product of this gene was detected by Western blot analysis. For details on the method see Tettelin et al. 2002.; hypothetical protein 640196..640801 Streptococcus agalactiae 2603V/R 1013455 NP_687672.1 CDS SAG0654 NC_004116.1 642197 642301 D hypothetical protein 642197..642301 Streptococcus agalactiae 2603V/R 1013458 NP_687673.1 CDS SAG0655 NC_004116.1 642734 642907 D hypothetical protein 642734..642907 Streptococcus agalactiae 2603V/R 1013459 NP_687674.1 CDS SAG0656 NC_004116.1 643279 643389 R hypothetical protein complement(643279..643389) Streptococcus agalactiae 2603V/R 1013460 NP_687675.1 CDS SAG0657 NC_004116.1 643420 643689 D hypothetical protein 643420..643689 Streptococcus agalactiae 2603V/R 1013461 NP_687676.1 CDS SAG0658 NC_004116.1 643750 644901 D similar to OMNI:EF0746; identified by sequence similarity; lipoprotein 643750..644901 Streptococcus agalactiae 2603V/R 1013462 NP_687677.1 CDS SAG0659 NC_004116.1 645101 646093 D identified by match to PFAM protein family HMM PF00005; ABC transporter ATP-binding protein 645101..646093 Streptococcus agalactiae 2603V/R 1013463 NP_687678.1 CDS SAG0660 NC_004116.1 646096 646914 D similar to OMNI:SP0637; identified by sequence similarity; hypothetical protein 646096..646914 Streptococcus agalactiae 2603V/R 1013464 NP_687679.1 CDS SAG0661 NC_004116.1 646916 647701 D hypothetical protein 646916..647701 Streptococcus agalactiae 2603V/R 1013465 NP_687680.1 CDS SAG0662 NC_004116.1 648326 648631 D similar to GP:4886770; identified by sequence similarity; cylX protein 648326..648631 Streptococcus agalactiae 2603V/R 1013466 NP_687681.1 CDS cylD NC_004116.1 648631 649479 D cylD protein 648631..649479 Streptococcus agalactiae 2603V/R 1013467 NP_687682.1 CDS cylG NC_004116.1 649476 650198 D identified by match to PFAM protein family HMM PF00106; cylG protein 649476..650198 Streptococcus agalactiae 2603V/R 1013468 NP_687683.1 CDS SAG0665 NC_004116.1 650191 650496 D acyl carrier protein 650191..650496 Streptococcus agalactiae 2603V/R 1013469 NP_687684.1 CDS SAG0666 NC_004116.1 650480 650956 D identified by match to PFAM protein family HMM PF01377; cylZ protein 650480..650956 Streptococcus agalactiae 2603V/R 1013470 NP_687685.1 CDS cylA NC_004116.1 650946 651875 D identified by match to PFAM protein family HMM PF00005; cylA protein 650946..651875 Streptococcus agalactiae 2603V/R 1013471 NP_687686.1 CDS cylB NC_004116.1 651868 652746 D cylB protein 651868..652746 Streptococcus agalactiae 2603V/R 1013472 NP_687687.1 CDS cylE NC_004116.1 652743 654746 D similar to GP:4886777; identified by sequence similarity; cylE protein 652743..654746 Streptococcus agalactiae 2603V/R 1013473 NP_687688.1 CDS cylF NC_004116.1 654743 655696 D identified by match to PFAM protein family HMM PF01571; cylF protein 654743..655696 Streptococcus agalactiae 2603V/R 1013474 NP_687689.1 CDS cylI NC_004116.1 655693 657888 D identified by match to PFAM protein family HMM PF00109; cylI protein 655693..657888 Streptococcus agalactiae 2603V/R 1013475 NP_687690.1 CDS cylJ NC_004116.1 657893 659104 D similar to GP:6007854; identified by sequence similarity; cylJ protein 657893..659104 Streptococcus agalactiae 2603V/R 1013476 NP_687691.1 CDS cylK NC_004116.1 659073 659648 D similar to GP:6007855; identified by sequence similarity; cylK protein 659073..659648 Streptococcus agalactiae 2603V/R 1013477 NP_687692.1 CDS SAG0674 NC_004116.1 659991 660332 D hypothetical protein 659991..660332 Streptococcus agalactiae 2603V/R 1013478 NP_687693.1 CDS SAG0675 NC_004116.1 660366 660881 D similar to SP:P16952; identified by sequence similarity; secreted protein 660366..660881 Streptococcus agalactiae 2603V/R 1013479 NP_687694.1 CDS SAG0676 NC_004116.1 660933 663590 D identified by match to PFAM protein family HMM PF00082; proteinase 660933..663590 Streptococcus agalactiae 2603V/R 1013480 NP_687695.1 CDS SAG0677 NC_004116.1 663693 666881 D identified by Glimmer2; The product of this gene was detected by Western blot analysis. For details on the method see Tettelin et al. 2002.; hypothetical protein 663693..666881 Streptococcus agalactiae 2603V/R 1013481 NP_687696.1 CDS SAG0679 NC_004116.1 669128 670159 D The product of this gene was detected by Western blot analysis. For details on the method see Tettelin et al. 2002.; hypothetical protein 669128..670159 Streptococcus agalactiae 2603V/R 1013483 NP_687697.1 CDS SAG0680 NC_004116.1 670194 671213 D The product of this gene was detected by Western blot analysis. For details on the method see Tettelin et al. 2002.; hypothetical protein 670194..671213 Streptococcus agalactiae 2603V/R 1013484 NP_687698.1 CDS SAG0681 NC_004116.1 671248 672309 D hypothetical protein 671248..672309 Streptococcus agalactiae 2603V/R 1013485 NP_687699.1 CDS SAG0682 NC_004116.1 672433 673662 D identified by match to PFAM protein family HMM PF02687; permease 672433..673662 Streptococcus agalactiae 2603V/R 1013486 NP_687700.1 CDS SAG0684 NC_004116.1 675121 675792 D identified by match to PFAM protein family HMM PF00005; ABC transporter ATP-binding protein 675121..675792 Streptococcus agalactiae 2603V/R 1013488 NP_687701.1 CDS SAG0685 NC_004116.1 675849 677267 R hypothetical protein complement(675849..677267) Streptococcus agalactiae 2603V/R 1013489 NP_687702.1 CDS SAG0686 NC_004116.1 677555 678340 D similar to SP:Q03158 GB:X54225 PID:47374; identified by sequence similarity; DNA-entry nuclease 677555..678340 Streptococcus agalactiae 2603V/R 1013490 NP_687703.1 CDS SAG0687 NC_004116.1 678418 679056 R identified by match to PFAM protein family HMM PF00597; DedA family protein complement(678418..679056) Streptococcus agalactiae 2603V/R 1013491 NP_687704.1 CDS SAG0688 NC_004116.1 679273 679929 D identified by match to PFAM protein family HMM PF00005; ABC transporter ATP-binding protein 679273..679929 Streptococcus agalactiae 2603V/R 1013492 NP_687705.1 CDS SAG0689 NC_004116.1 679926 680699 D identified by match to TIGR protein family HMM TIGR00245; hypothetical protein 679926..680699 Streptococcus agalactiae 2603V/R 1013493 NP_687706.1 CDS SAG0690 NC_004116.1 680863 681681 D hypothetical protein 680863..681681 Streptococcus agalactiae 2603V/R 1013494 NP_687707.1 CDS SAG0691 NC_004116.1 681718 682602 R identified by match to PFAM protein family HMM PF00126; LysR family transcriptional regulator complement(681718..682602) Streptococcus agalactiae 2603V/R 1013495 NP_687708.1 CDS SAG0692 NC_004116.1 682795 683376 D similar to GP:5901699; identified by sequence similarity; regulatory protein 682795..683376 Streptococcus agalactiae 2603V/R 1013496 NP_687709.1 CDS SAG0693 NC_004116.1 683390 684523 R identified by match to PFAM protein family HMM PF01609; IS1548 transposase complement(683390..684523) Streptococcus agalactiae 2603V/R 1013497 NP_687710.1 CDS ldhA NC_004116.1 685192 686184 D catalyzes the formation of pyruvate from lactate; D-lactate dehydrogenase 685192..686184 Streptococcus agalactiae 2603V/R 1013499 NP_687711.1 CDS SAG0696 NC_004116.1 686391 687941 D sugar transporter 686391..687941 Streptococcus agalactiae 2603V/R 1013500 NP_687712.1 CDS SAG0697 NC_004116.1 688008 689033 D identified by match to PFAM protein family HMM PF00294; 2-keto-3-deoxygluconate kinase 688008..689033 Streptococcus agalactiae 2603V/R 1013501 NP_687713.1 CDS SAG0698 NC_004116.1 689050 690849 D identified by match to PFAM protein family HMM PF00703; beta-D-glucuronidase 689050..690849 Streptococcus agalactiae 2603V/R 1013502 NP_687714.1 CDS SAG0699 NC_004116.1 690878 691549 D identified by match to PFAM protein family HMM PF00392; GntR family transcriptional regulator 690878..691549 Streptococcus agalactiae 2603V/R 1013503 NP_687715.1 CDS eda-1 NC_004116.1 691666 692283 D identified by match to PFAM protein family HMM PF01081; 2-dehydro-3-deoxyphosphooctonate aldolase 691666..692283 Streptococcus agalactiae 2603V/R 1013504 NP_687716.1 CDS uxaC NC_004116.1 692300 693700 D catalyzes the interconversion of D-glucuronate to D-fructuronate or D-galacturonate to D-tagaturonate; functions in glucuronic and galacturonic metabolism; glucuronate isomerase 692300..693700 Streptococcus agalactiae 2603V/R 1013505 NP_687717.1 CDS uxuA NC_004116.1 693718 694764 D catalyzes the formation of 2-dehydro-3-deoxy-D-gluconate from mannonate; mannonate dehydratase 693718..694764 Streptococcus agalactiae 2603V/R 1013506 NP_687718.1 CDS SAG0703 NC_004116.1 694888 695727 D Converts D-mannonate to D-mannuronate; D-mannonate oxidoreductase 694888..695727 Streptococcus agalactiae 2603V/R 1013507 NP_687719.1 CDS SAG0704 NC_004116.1 695880 696692 D identified by match to PFAM protein family HMM PF00702; HAD superfamily hydrolase 695880..696692 Streptococcus agalactiae 2603V/R 1013508 NP_687720.1 CDS SAG0705 NC_004116.1 696708 698498 D identified by match to PFAM protein family HMM PF00933; glycosyl hydrolase family protein 696708..698498 Streptococcus agalactiae 2603V/R 1013509 NP_687721.1 CDS pepQ NC_004116.1 698556 699641 R identified by match to PFAM protein family HMM PF00557; proline dipeptidase complement(698556..699641) Streptococcus agalactiae 2603V/R 1013510 NP_687722.1 CDS SAG0707 NC_004116.1 699851 700855 D identified by match to PFAM protein family HMM PF00356; RegM family transcriptional regulator 699851..700855 Streptococcus agalactiae 2603V/R 1013511 NP_687723.1 CDS SAG0708 NC_004116.1 700987 702453 D converts 1,4-alpha-D-glucans to maltodextrin; alpha-amylase 700987..702453 Streptococcus agalactiae 2603V/R 1013512 NP_687724.1 CDS SAG0709 NC_004116.1 702498 703496 D identified by match to PFAM protein family HMM PF00534; glycoside hydrolase family protein 702498..703496 Streptococcus agalactiae 2603V/R 1013513 NP_687725.1 CDS SAG0710 NC_004116.1 703498 704832 D identified by match to PFAM protein family HMM PF00534; glycoside hydrolase family protein 703498..704832 Streptococcus agalactiae 2603V/R 1013514 NP_687726.1 CDS thrS NC_004116.1 705289 707232 D catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr); threonyl-tRNA synthetase 705289..707232 Streptococcus agalactiae 2603V/R 1013515 NP_687727.1 CDS SAG0712 NC_004116.1 707454 708158 D identified by match to PFAM protein family HMM PF00072; DNA-binding response regulator 707454..708158 Streptococcus agalactiae 2603V/R 1013516 NP_687728.1 CDS SAG0713 NC_004116.1 708256 709275 D hypothetical protein 708256..709275 Streptococcus agalactiae 2603V/R 1013517 NP_687729.1 CDS SAG0714 NC_004116.1 709443 710009 D hypothetical protein 709443..710009 Streptococcus agalactiae 2603V/R 1013518 NP_687730.1 CDS SAG0715 NC_004116.1 710058 710708 R identified by match to PFAM protein family HMM PF00528; amino acid ABC transporter permease complement(710058..710708) Streptococcus agalactiae 2603V/R 1013519 NP_687731.1 CDS SAG0716 NC_004116.1 710720 711415 R identified by match to PFAM protein family HMM PF00528; amino acid ABC transporter permease complement(710720..711415) Streptococcus agalactiae 2603V/R 1013520 NP_687732.1 CDS SAG0717 NC_004116.1 711428 712228 R identified by match to PFAM protein family HMM PF00497; amino acid ABC transporter amino acid-binding protein complement(711428..712228) Streptococcus agalactiae 2603V/R 1013521 NP_687733.1 CDS SAG0718 NC_004116.1 712240 712995 R identified by match to PFAM protein family HMM PF00005; amino acid ABC transporter ATP-binding protein complement(712240..712995) Streptococcus agalactiae 2603V/R 1013522 NP_687734.1 CDS SAG0719 NC_004116.1 713335 714045 D identified by match to PFAM protein family HMM PF00072; DNA-binding response regulator 713335..714045 Streptococcus agalactiae 2603V/R 1013523 NP_687735.1 CDS SAG0720 NC_004116.1 714038 715387 D identified by match to PFAM protein family HMM PF00512; sensory box histidine kinase 714038..715387 Streptococcus agalactiae 2603V/R 1013524 NP_687736.1 CDS SAG0721 NC_004116.1 715391 716200 D identified by match to PFAM protein family HMM PF00753; metallo-beta-lactamase superfamily protein 715391..716200 Streptococcus agalactiae 2603V/R 1013525 NP_687737.1 CDS SAG0722 NC_004116.1 716203 716571 D hypothetical protein 716203..716571 Streptococcus agalactiae 2603V/R 1013526 NP_687738.1 CDS rnc NC_004116.1 716723 717433 D cytoplasmic enzyme involved in processing rRNA and some mRNAs; substrates typically have dsRNA regions; forms a homodimer; have N-terminal nuclease and C-terminal RNA-binding domains; requires magnesium as preferred ion for activity; ribonuclease III 716723..717433 Streptococcus agalactiae 2603V/R 1013527 NP_687739.1 CDS SAG0724 NC_004116.1 717441 720980 D identified by match to PFAM protein family HMM PF02463; The product of this gene was detected by Western blot analysis. For details on the method see Tettelin et al. 2002.; chromosome segregation protein SMC 717441..720980 Streptococcus agalactiae 2603V/R 1013528 NP_687740.1 CDS SAG0725 NC_004116.1 721071 721868 D identified by match to PFAM protein family HMM PF00702; HAD superfamily hydrolase 721071..721868 Streptococcus agalactiae 2603V/R 1013529 NP_687741.1 CDS SAG0726 NC_004116.1 721868 722692 D identified by match to PFAM protein family HMM PF00702; HAD superfamily hydrolase 721868..722692 Streptococcus agalactiae 2603V/R 1013530 NP_687742.1 CDS ftsY NC_004116.1 722692 724302 D identified by match to PFAM protein family HMM PF00448; signal recognition particle-docking protein FtsY 722692..724302 Streptococcus agalactiae 2603V/R 1013531 NP_687743.1 CDS SAG0728 NC_004116.1 724339 725151 R similar to OMNI:NTL01SPL0427; identified by sequence similarity; hypothetical protein complement(724339..725151) Streptococcus agalactiae 2603V/R 1013532 NP_687744.1 CDS SAG0729 NC_004116.1 725151 726053 R similar to OMNI:NTL01SPL0428; identified by sequence similarity; ABC transporter permease complement(725151..726053) Streptococcus agalactiae 2603V/R 1013533 NP_687745.1 CDS SAG0730 NC_004116.1 726059 726187 R similar to OMNI:NTL01SPL0429; identified by sequence similarity; hypothetical protein complement(726059..726187) Streptococcus agalactiae 2603V/R 1013534 NP_687746.1 CDS SAG0731 NC_004116.1 726320 727363 D identified by match to PFAM protein family HMM PF00296; luciferase family protein 726320..727363 Streptococcus agalactiae 2603V/R 1013535 NP_687747.1 CDS SAG0732 NC_004116.1 727468 729630 D identified by match to PFAM protein family HMM PF00575; transcriptional accessory protein Tex 727468..729630 Streptococcus agalactiae 2603V/R 1013536 NP_687748.1 CDS SAG0733 NC_004116.1 729623 730051 D hypothetical protein 729623..730051 Streptococcus agalactiae 2603V/R 1013537 NP_687749.1 CDS SAG0734 NC_004116.1 730132 730395 D similar to SP:P23855 GB:X57560 PID:42541 GB:U00096 PID:1742136; identified by sequence similarity; phage shock protein C 730132..730395 Streptococcus agalactiae 2603V/R 1013538 NP_687750.1 CDS SAG0735 NC_004116.1 730373 730507 D hypothetical protein 730373..730507 Streptococcus agalactiae 2603V/R 1013539 NP_687751.1 CDS hprK NC_004116.1 730623 731558 D catalyzes the phosphorylation of the phosphocarrier protein HPr of the bacterial phosphotransferase system; HPr kinase/phosphorylase 730623..731558 Streptococcus agalactiae 2603V/R 1013540 NP_687752.1 CDS lgt NC_004116.1 731551 732324 D transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein; prolipoprotein diacylglyceryl transferase 731551..732324 Streptococcus agalactiae 2603V/R 1013541 NP_687753.1 CDS SAG0738 NC_004116.1 732339 732737 D hypothetical protein 732339..732737 Streptococcus agalactiae 2603V/R 1013542 NP_687754.1 CDS SAG0739 NC_004116.1 732734 733165 D hypothetical protein 732734..733165 Streptococcus agalactiae 2603V/R 1013543 NP_687755.1 CDS SAG0740 NC_004116.1 733206 733481 R hypothetical protein complement(733206..733481) Streptococcus agalactiae 2603V/R 1013544 NP_687756.1 CDS SAG0741 NC_004116.1 733836 734747 D hypothetical protein 733836..734747 Streptococcus agalactiae 2603V/R 1013545 NP_687757.1 CDS SAG0742 NC_004116.1 734877 736163 D identified by match to PFAM protein family HMM PF01136; U32 family peptidase 734877..736163 Streptococcus agalactiae 2603V/R 1013546 NP_687758.1 CDS SAG0743 NC_004116.1 736290 736502 D hypothetical protein 736290..736502 Streptococcus agalactiae 2603V/R 1013547 NP_687759.1 CDS SAG0744 NC_004116.1 736626 737423 D hypothetical protein 736626..737423 Streptococcus agalactiae 2603V/R 1013548 NP_687760.1 CDS SAG0745 NC_004116.1 737525 738865 R identified by match to PFAM protein family HMM PF01566; Mn2+/Fe2+ transporter complement(737525..738865) Streptococcus agalactiae 2603V/R 1013549 NP_687761.1 CDS ribD NC_004116.1 739594 740703 D identified by match to PFAM protein family HMM PF00383; riboflavin biosynthesis protein RibD 739594..740703 Streptococcus agalactiae 2603V/R 1013550 NP_687762.2 CDS ribE NC_004116.1 740684 741334 D catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine; riboflavin synthase subunit alpha 740684..741334 Streptococcus agalactiae 2603V/R 1013551 NP_687763.1 CDS ribA NC_004116.1 741352 742545 D identified by match to PFAM protein family HMM PF00925; riboflavin biosynthesis protein RibA 741352..742545 Streptococcus agalactiae 2603V/R 1013552 NP_687764.1 CDS ribH NC_004116.1 742560 743030 D RibE; 6,7-diimethyl-8-ribityllumazine synthase; DMRL synthase; lumazine synthase; beta subunit of riboflavin synthase; condenses 5-amino-6-(1'-D)-ribityl-amino-2,4(1H,3H)-pyrimidinedione with L-3,4-dihydrohy-2-butanone-4-phosphate to generate 6,6-dimethyl-8-lumazine (DMRL); riboflavin synthase then uses 2 molecules of DMRL to produce riboflavin (vitamin B12); involved in the last steps of riboflavin biosynthesis; forms a 60mer (icosahedral shell) in both Bacillus subtilis and Escherichia coli; in Bacillus subtilis this 60mer is associated with the riboflavin synthase subunit (alpha) while in Escherichia coli it is not; 6,7-dimethyl-8-ribityllumazine synthase 742560..743030 Streptococcus agalactiae 2603V/R 1013553 NP_687765.1 CDS lysS NC_004116.1 743105 744595 R class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1; lysyl-tRNA synthetase complement(743105..744595) Streptococcus agalactiae 2603V/R 1013554 NP_687766.1 CDS SAG0751 NC_004116.1 744770 745672 D identified by match to PFAM protein family HMM PF00702; HAD superfamily hydrolase 744770..745672 Streptococcus agalactiae 2603V/R 1013555 NP_687767.1 CDS SAG0752 NC_004116.1 745708 746349 R identified by match to PFAM protein family HMM PF00300; phosphoglycerate mutase family protein complement(745708..746349) Streptococcus agalactiae 2603V/R 1013556 NP_687768.1 CDS SAG0753 NC_004116.1 746371 746844 R EbsC family transcriptional regulator complement(746371..746844) Streptococcus agalactiae 2603V/R 1013557 NP_687769.1 CDS SAG0754 NC_004116.1 747139 747756 D hypothetical protein 747139..747756 Streptococcus agalactiae 2603V/R 1013558 NP_687770.1 CDS SAG0755 NC_004116.1 747789 748637 R similar to OMNI:NTL01SPL0447; identified by sequence similarity; U32 family peptidase complement(747789..748637) Streptococcus agalactiae 2603V/R 1013559 NP_687771.1 CDS SAG0756 NC_004116.1 748793 749317 D hypothetical protein 748793..749317 Streptococcus agalactiae 2603V/R 1013560 NP_687772.1 CDS SAG0757 NC_004116.1 749301 749690 D similar to GP:13621804; identified by sequence similarity; The product of this gene was detected by Western blot analysis. For details on the method see Tettelin et al. 2002.; hypothetical protein 749301..749690 Streptococcus agalactiae 2603V/R 1013561 NP_687773.1 CDS SAG0758 NC_004116.1 749749 751548 R identified by match to PFAM protein family HMM PF01432; oligoendopeptidase F complement(749749..751548) Streptococcus agalactiae 2603V/R 1013562 NP_687774.1 CDS ppc NC_004116.1 751757 754552 D catalyzes the formation of oxaloacetate from phosphoenolpyruvate; phosphoenolpyruvate carboxylase 751757..754552 Streptococcus agalactiae 2603V/R 1013563 NP_687775.1 CDS SAG0760 NC_004116.1 754678 755811 D identified by match to PFAM protein family HMM PF01609; IS1548 transposase 754678..755811 Streptococcus agalactiae 2603V/R 1013564 NP_687776.1 CDS ftsW NC_004116.1 755984 757252 D identified by match to PFAM protein family HMM PF01098; cell cycle protein FtsW 755984..757252 Streptococcus agalactiae 2603V/R 1013565 NP_687777.1 CDS tuf NC_004116.1 757604 758800 D EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu; elongation factor Tu 757604..758800 Streptococcus agalactiae 2603V/R 1013566 NP_687778.1 CDS tpiA NC_004116.1 758981 759739 D Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate; triosephosphate isomerase 758981..759739 Streptococcus agalactiae 2603V/R 1013567 NP_687779.1 CDS gpmA NC_004116.1 759916 760608 D 2,3-bisphosphoglycerate-dependent; catalyzes the interconversion of 2-phosphoglycerate to 3-phosphoglycerate; phosphoglyceromutase 759916..760608 Streptococcus agalactiae 2603V/R 1013568 NP_687780.1 CDS SAG0765 NC_004116.1 760737 762782 D identified by match to PFAM protein family HMM PF00905; penicillin-binding protein 2b 760737..762782 Streptococcus agalactiae 2603V/R 1013569 NP_687781.1 CDS recR NC_004116.1 762797 763393 D involved in a recombinational process of DNA repair, independent of the recBC complex; recombination protein RecR 762797..763393 Streptococcus agalactiae 2603V/R 1013570 NP_687782.1 CDS ddl NC_004116.1 763534 764580 D D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli; D-alanyl-alanine synthetase A 763534..764580 Streptococcus agalactiae 2603V/R 1013571 NP_687783.1 CDS murF NC_004116.1 764727 766094 D identified by match to PFAM protein family HMM PF01225; UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate--D-alanyl-D-alanyl ligase 764727..766094 Streptococcus agalactiae 2603V/R 1013572 NP_687784.1 CDS SAG0769 NC_004116.1 766281 767501 D identified by match to PFAM protein family HMM PF00083; oxalate:formate antiporter 766281..767501 Streptococcus agalactiae 2603V/R 1013573 NP_687785.1 CDS SAG0770 NC_004116.1 767630 768316 D similar to OMNI:SP1668; identified by sequence similarity; hypothetical protein 767630..768316 Streptococcus agalactiae 2603V/R 1013574 NP_687786.1 CDS SAG0771 NC_004116.1 768495 770033 D identified by match to TIGR protein family HMM TIGR01167; cell wall surface anchor family protein 768495..770033 Streptococcus agalactiae 2603V/R 1013575 NP_687787.1 CDS prfC NC_004116.1 770210 771754 D stimulates the release of release factors 1 and 2 from the ribosome after hydrolysis of the ester bond in peptidyl-tRNA has occurred; GDP/GTP-binding protein; peptide chain release factor 3 770210..771754 Streptococcus agalactiae 2603V/R 1013576 NP_687788.1 CDS SAG0773 NC_004116.1 771840 772220 D hypothetical protein 771840..772220 Streptococcus agalactiae 2603V/R 1013577 NP_687789.1 CDS SAG0774 NC_004116.1 772341 773075 D identified by match to PFAM protein family HMM PF00005; ABC transporter ATP-binding protein 772341..773075 Streptococcus agalactiae 2603V/R 1013578 NP_687790.1 CDS SAG0775 NC_004116.1 773068 773730 D identified by match to PFAM protein family HMM PF00528; ABC transporter permease 773068..773730 Streptococcus agalactiae 2603V/R 1013579 NP_687791.1 CDS SAG0776 NC_004116.1 773746 774576 D identified by match to PFAM protein family HMM PF03180; YaeC family protein 773746..774576 Streptococcus agalactiae 2603V/R 1013580 NP_687792.1 CDS SAG0777 NC_004116.1 774811 776397 D identified by match to PFAM protein family HMM PF00270; DEAD/DEAH box helicase 774811..776397 Streptococcus agalactiae 2603V/R 1013581 NP_687793.1 CDS SAG0778 NC_004116.1 776582 776848 R hypothetical protein complement(776582..776848) Streptococcus agalactiae 2603V/R 1013582 NP_687794.1 CDS SAG0779 NC_004116.1 776841 777605 R hypothetical protein complement(776841..777605) Streptococcus agalactiae 2603V/R 1013583 NP_687795.1 CDS SAG0780 NC_004116.1 777740 778480 D identified by match to PFAM protein family HMM PF01553; acyltransferase 777740..778480 Streptococcus agalactiae 2603V/R 1013584 NP_687796.1 CDS celA NC_004116.1 778580 779233 D identified by match to PFAM protein family HMM PF00633; competence protein CelA 778580..779233 Streptococcus agalactiae 2603V/R 1013585 NP_687797.1 CDS SAG0782 NC_004116.1 779217 781454 D identified by match to PFAM protein family HMM PF00753; DNA internalization-related competence protein ComEC/Rec2 779217..781454 Streptococcus agalactiae 2603V/R 1013586 NP_687798.1 CDS SAG0783 NC_004116.1 781580 782389 D identified by match to PFAM protein family HMM PF00702; HAD superfamily hydrolase 781580..782389 Streptococcus agalactiae 2603V/R 1013587 NP_687799.1 CDS SAG0784 NC_004116.1 782400 783344 D identified by match to PFAM protein family HMM PF00356; LacI family sugar-binding transcriptional regulator 782400..783344 Streptococcus agalactiae 2603V/R 1013588 NP_687800.1 CDS SAG0785 NC_004116.1 783403 784395 R hypothetical protein complement(783403..784395) Streptococcus agalactiae 2603V/R 1013589 NP_687801.1 CDS SAG0786 NC_004116.1 784571 785299 D hypothetical protein 784571..785299 Streptococcus agalactiae 2603V/R 1013590 NP_687802.1 CDS holA NC_004116.1 785353 786390 D required for the assembly and function of the DNAX complex which is required for the assembly of the beta subunit onto primed DNA; DNA polymerase III subunit delta 785353..786390 Streptococcus agalactiae 2603V/R 1013591 NP_687803.1 CDS sodA NC_004116.1 786470 787078 D identified by match to PFAM protein family HMM PF00081; superoxide dismutase 786470..787078 Streptococcus agalactiae 2603V/R 1013592 NP_687804.1 CDS SAG0789 NC_004116.1 787416 788267 D identified by match to PFAM protein family HMM PF00874; transcriptional antiterminator LicT 787416..788267 Streptococcus agalactiae 2603V/R 1013593 NP_687805.1 CDS SAG0790 NC_004116.1 788260 790128 D identified by match to PFAM protein family HMM PF00358; PTS system beta-glucosides-specific transporter subunit IIABC 788260..790128 Streptococcus agalactiae 2603V/R 1013594 NP_687806.1 CDS bglA NC_004116.1 790145 791572 D identified by match to PFAM protein family HMM PF00232; 6-phospho-beta-glucosidase 790145..791572 Streptococcus agalactiae 2603V/R 1013595 NP_687807.1 CDS SAG0792 NC_004116.1 791641 792735 R hypothetical protein complement(791641..792735) Streptococcus agalactiae 2603V/R 1013596 NP_687808.1 CDS garK NC_004116.1 792902 794044 D identified by match to PFAM protein family HMM PF02595; The product of this gene was detected by Western blot analysis. For details on the method see Tettelin et al. 2002.; glycerate kinase 792902..794044 Streptococcus agalactiae 2603V/R 1013597 NP_687809.1 CDS SAG0794 NC_004116.1 794069 795325 D identified by match to PFAM protein family HMM PF02447; GntP family permease 794069..795325 Streptococcus agalactiae 2603V/R 1013598 NP_687810.1 CDS SAG0795 NC_004116.1 795426 796490 D hypothetical protein 795426..796490 Streptococcus agalactiae 2603V/R 1013599 NP_687811.1 CDS SAG0796 NC_004116.1 796545 796988 R identified by match to PFAM protein family HMM PF01047; MarR family transcriptional regulator complement(796545..796988) Streptococcus agalactiae 2603V/R 1013600 NP_687812.1 CDS queA NC_004116.1 797069 798097 R Synthesizes oQ from preQ1 in a single S-adenosylmethionine-requiring step; S-adenosylmethionine--tRNA ribosyltransferase-isomerase complement(797069..798097) Streptococcus agalactiae 2603V/R 1013601 NP_687813.1 CDS SAG0798 NC_004116.1 798250 798930 D hypothetical protein 798250..798930 Streptococcus agalactiae 2603V/R 1013602 NP_687814.1 CDS nagB NC_004116.1 799081 799782 D identified by match to PFAM protein family HMM PF01182; glucosamine-6-phosphate isomerase 799081..799782 Streptococcus agalactiae 2603V/R 1013603 NP_687815.1 CDS SAG0800 NC_004116.1 799854 800810 R identified by match to PFAM protein family HMM PF00043; glutathione S-transferase family protein complement(799854..800810) Streptococcus agalactiae 2603V/R 1013604 NP_687816.1 CDS SAG0801 NC_004116.1 800906 801625 D identified by match to PFAM protein family HMM PF00849; ribosomal small subunit pseudouridine synthase A 800906..801625 Streptococcus agalactiae 2603V/R 1013605 NP_687817.1 CDS SAG0802 NC_004116.1 801600 801716 R hypothetical protein complement(801600..801716) Streptococcus agalactiae 2603V/R 1013606 NP_687818.1 CDS SAG0803 NC_004116.1 801698 802849 D identified by match to PFAM protein family HMM PF00083; major facilitator family protein 801698..802849 Streptococcus agalactiae 2603V/R 1013607 NP_687819.1 CDS coiA NC_004116.1 802901 803848 D similar to OMNI:SP0978; identified by sequence similarity; competence protein CoiA 802901..803848 Streptococcus agalactiae 2603V/R 1013608 NP_687820.1 CDS pepB NC_004116.1 803864 805669 D identified by match to PFAM protein family HMM PF01432; group B oligopeptidase PepB 803864..805669 Streptococcus agalactiae 2603V/R 1013609 NP_687821.1 CDS SAG0806 NC_004116.1 805864 806490 D identified by match to PFAM protein family HMM PF00702; HAD superfamily hydrolase 805864..806490 Streptococcus agalactiae 2603V/R 1013610 NP_687822.1 CDS SAG0807 NC_004116.1 806564 807271 D identified by match to PFAM protein family HMM PF01596; O-methyltransferase family protein 806564..807271 Streptococcus agalactiae 2603V/R 1013611 NP_687823.1 CDS prsA NC_004116.1 807332 808261 D cis/trans isomerase of peptidylprolyl; PPIase; membrane-bound lipoprotein; foldase protein PrsA 807332..808261 Streptococcus agalactiae 2603V/R 1013612 NP_687824.1 CDS SAG0809 NC_004116.1 808503 808988 D hypothetical protein 808503..808988 Streptococcus agalactiae 2603V/R 1013613 NP_687825.1 CDS alaS NC_004116.1 809004 811622 D Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; alanyl-tRNA synthetase 809004..811622 Streptococcus agalactiae 2603V/R 1013614 NP_687826.1 CDS SAG0811 NC_004116.1 811704 812420 D similar to OMNI:NTL01BH4061; identified by sequence similarity; hypothetical protein 811704..812420 Streptococcus agalactiae 2603V/R 1013615 NP_687827.1 CDS SAG0812 NC_004116.1 812508 813326 D identified by match to PFAM protein family HMM PF01501; glycosyl transferase family protein 812508..813326 Streptococcus agalactiae 2603V/R 1013616 NP_687828.1 CDS SAG0813 NC_004116.1 813470 813715 D hypothetical protein 813470..813715 Streptococcus agalactiae 2603V/R 1013617 NP_687829.1 CDS SAG0814 NC_004116.1 813754 814041 D hypothetical protein 813754..814041 Streptococcus agalactiae 2603V/R 1013618 NP_687830.1 CDS SAG0815 NC_004116.1 814086 814301 D identified by match to PFAM protein family HMM PF01381; Cro/CI family transcriptional regulator 814086..814301 Streptococcus agalactiae 2603V/R 1013619 NP_687831.1 CDS SAG0816 NC_004116.1 814301 815062 D similar to OMNI:NTL01SPL1088; identified by sequence similarity; hypothetical protein 814301..815062 Streptococcus agalactiae 2603V/R 1013620 NP_687832.1 CDS SAG0817 NC_004116.1 815147 815710 R similar to OMNI:NTL01SPL0446; identified by sequence similarity; hypothetical protein complement(815147..815710) Streptococcus agalactiae 2603V/R 1013621 NP_687833.1 CDS nrdF NC_004116.1 815951 816910 R B2 or R2 protein; type 1b enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdE; ribonucleotide-diphosphate reductase subunit beta complement(815951..816910) Streptococcus agalactiae 2603V/R 1013622 NP_687834.1 CDS nrdE-2 NC_004116.1 817113 819272 R Catalyzes the rate-limiting step in dNTP synthesis; ribonucleotide-diphosphate reductase subunit alpha complement(817113..819272) Streptococcus agalactiae 2603V/R 1013623 NP_687835.1 CDS nrdH NC_004116.1 819350 819574 R ribonucleoside-diphosphate reductase 2, NrdH-redoxin complement(819350..819574) Streptococcus agalactiae 2603V/R 1013624 NP_687836.1 CDS ptsH NC_004116.1 819957 820220 D identified by match to PFAM protein family HMM PF00381; phosphocarrier protein HPr 819957..820220 Streptococcus agalactiae 2603V/R 1013625 NP_687837.1 CDS ptsI NC_004116.1 820225 821958 D identified by match to PFAM protein family HMM PF00391; phosphoenolpyruvate-protein phosphotransferase 820225..821958 Streptococcus agalactiae 2603V/R 1013626 NP_687838.1 CDS gapN NC_004116.1 822108 823535 D identified by match to PFAM protein family HMM PF00171; glyceraldehyde-3-phosphate dehydrogenase 822108..823535 Streptococcus agalactiae 2603V/R 1013627 NP_687839.1 CDS SAG0824 NC_004116.1 823675 824928 D identified by match to PFAM protein family HMM PF01522; polysaccharide deacetylase 823675..824928 Streptococcus agalactiae 2603V/R 1013628 NP_687840.1 CDS SAG0825 NC_004116.1 824961 826043 R identified by match to PFAM protein family HMM PF00270; DEAD/DEAH box helicase complement(824961..826043) Streptococcus agalactiae 2603V/R 1013629 NP_687841.1 CDS udk NC_004116.1 826188 826817 D functions in pyrimidine salvage; pyrimidine ribonucleoside kinase; phosphorylates nucleosides or dinucleosides to make UMP or CMP using ATP or GTP as the donor; uridine kinase 826188..826817 Streptococcus agalactiae 2603V/R 1013630 NP_687842.1 CDS SAG0827 NC_004116.1 826904 827401 D hypothetical protein 826904..827401 Streptococcus agalactiae 2603V/R 1013631 NP_687843.1 CDS dnaX NC_004116.1 827401 829065 D catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the tau chain serves as a scaffold to help in the dimerizaton of the alpha,epsilon and theta core complex; the gamma chain seems to interact with the delta and delta' subunits to transfer the beta subunit on the DNA; DNA polymerase III subunits gamma and tau 827401..829065 Streptococcus agalactiae 2603V/R 1013632 NP_687844.1 CDS SAG0829 NC_004116.1 829154 829348 D hypothetical protein 829154..829348 Streptococcus agalactiae 2603V/R 1013633 NP_687845.1 CDS SAG0830 NC_004116.1 829329 830264 R catalyzes the formation of biotinyl-5'-AMP, also acts as a transcriptional repressor of the biotin operon; biotin--protein ligase complement(829329..830264) Streptococcus agalactiae 2603V/R 1013634 NP_687846.1 CDS metK NC_004116.1 830449 831645 D methionine adenosyltransferase; catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase; S-adenosylmethionine synthetase 830449..831645 Streptococcus agalactiae 2603V/R 1013635 NP_687847.1 CDS SAG0832 NC_004116.1 832166 834427 D identified by Glimmer2; The product of this gene was detected by Western blot analysis. For details on the method see Tettelin et al. 2002.; hypothetical protein 832166..834427 Streptococcus agalactiae 2603V/R 1013636 NP_687848.1 CDS SAG0833 NC_004116.1 834494 835039 D hypothetical protein 834494..835039 Streptococcus agalactiae 2603V/R 1013637 NP_687849.1 CDS SAG0834 NC_004116.1 835199 835327 D hypothetical protein 835199..835327 Streptococcus agalactiae 2603V/R 1013638 NP_687850.1 CDS SAG0835 NC_004116.1 835435 836001 D hypothetical protein 835435..836001 Streptococcus agalactiae 2603V/R 1013639 NP_687851.1 CDS SAG0836 NC_004116.1 835998 836552 D hypothetical protein 835998..836552 Streptococcus agalactiae 2603V/R 1013640 NP_687852.1 CDS SAG0837 NC_004116.1 836556 837842 D identified by match to PFAM protein family HMM PF00005; ABC transporter ATP-binding protein 836556..837842 Streptococcus agalactiae 2603V/R 1013641 NP_687853.1 CDS SAG0838 NC_004116.1 837797 838498 D hypothetical protein 837797..838498 Streptococcus agalactiae 2603V/R 1013642 NP_687854.1 CDS SAG0839 NC_004116.1 838582 839262 D identified by match to PFAM protein family HMM PF03070; TenA family transcriptional regulator 838582..839262 Streptococcus agalactiae 2603V/R 1013643 NP_687855.1 CDS thiD NC_004116.1 839264 840061 D catalyzes the formation of 4-amino-2-methyl-5-diphosphomethylpyrimidine; phosphomethylpyrimidine kinase 839264..840061 Streptococcus agalactiae 2603V/R 1013644 NP_687856.1 CDS thiM NC_004116.1 840063 840833 D catalyzes the formation of 4-methyl-5-(2-phosphoethyl)-thiazole and ADP from 4-methyl-5-(2-hydroxyethyl)-thiazole and ATP; hydroxyethylthiazole kinase 840063..840833 Streptococcus agalactiae 2603V/R 1013645 NP_687857.1 CDS thiE NC_004116.1 840847 841518 D Condenses 4-methyl-5-(beta-hydroxyethyl)-thiazole monophosphate and 4-amino-5-hydroxymethyl pyrimidine pyrophosphate to form thiamine monophosphate; thiamine-phosphate pyrophosphorylase 840847..841518 Streptococcus agalactiae 2603V/R 1013646 NP_687858.1 CDS murA-1 NC_004116.1 841645 842904 D adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active; UDP-N-acetylglucosamine 1-carboxyvinyltransferase 841645..842904 Streptococcus agalactiae 2603V/R 1013647 NP_687859.1 CDS SAG0844 NC_004116.1 843006 843560 D identified by match to PFAM protein family HMM PF00583; acetyltransferase 843006..843560 Streptococcus agalactiae 2603V/R 1013648 NP_687860.1 CDS SAG0845 NC_004116.1 843553 844836 D identified by match to PFAM protein family HMM PF00571; hypothetical protein 843553..844836 Streptococcus agalactiae 2603V/R 1013649 NP_687861.1 CDS map NC_004116.1 844859 845719 D catalyzes the removal of N-terminal amino acids from peptides and arylamides; methionine aminopeptidase 844859..845719 Streptococcus agalactiae 2603V/R 1013650 NP_687862.1 CDS SAG0847 NC_004116.1 845721 846641 D identified by match to TIGR protein family HMM TIGR00765; ribonuclease BN 845721..846641 Streptococcus agalactiae 2603V/R 1013651 NP_687863.1 CDS SAG0848 NC_004116.1 846658 847113 R similar to GB:X73124 SP:P39602 PID:413958 GB:AL009126; identified by sequence similarity; GtrA family protein complement(846658..847113) Streptococcus agalactiae 2603V/R 1013652 NP_687864.1 CDS SAG0849 NC_004116.1 847295 847804 D hypothetical protein 847295..847804 Streptococcus agalactiae 2603V/R 1013653 NP_687865.1 CDS ligA NC_004116.1 847944 849902 D this protein catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction; essential for DNA replication and repair of damaged DNA; similar to ligase LigB; NAD-dependent DNA ligase LigA 847944..849902 Streptococcus agalactiae 2603V/R 1013654 NP_687866.1 CDS SAG0851 NC_004116.1 849914 850933 D similar to YegS from E. coli; lipid kinase 849914..850933 Streptococcus agalactiae 2603V/R 1013655 NP_687867.1 CDS SAG0852 NC_004116.1 850937 853237 D identified by match to PFAM protein family HMM PF00128; pullulanase 850937..853237 Streptococcus agalactiae 2603V/R 1013656 NP_687868.1 CDS glgB NC_004116.1 853443 855311 D catalyzes the transfer of a segment of a 1,4-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain; glycogen branching protein 853443..855311 Streptococcus agalactiae 2603V/R 1013657 NP_687869.1 CDS glgC NC_004116.1 855353 856492 D catalyzes the formation of ADP-glucose and diphosphate from ATP and alpha-D-glucose 1-phosphate; glucose-1-phosphate adenylyltransferase 855353..856492 Streptococcus agalactiae 2603V/R 1013658 NP_687870.1 CDS glgA NC_004116.1 857611 859041 D catalyzes the formation of alpha-1,4-glucan chains from ADP-glucose; glycogen synthase 857611..859041 Streptococcus agalactiae 2603V/R 1013660 NP_687871.1 CDS atpE NC_004116.1 859373 859573 D produces ATP from ADP in the presence of a proton gradient across the membrane; subunit C is part of the membrane proton channel F0; ATP synthase F0F1 subunit C 859373..859573 Streptococcus agalactiae 2603V/R 1013661 NP_687872.1 CDS atpB NC_004116.1 859606 860322 D Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0; ATP synthase F0F1 subunit A 859606..860322 Streptococcus agalactiae 2603V/R 1013662 NP_687873.1 CDS atpF NC_004116.1 860340 860837 D Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit B is part of the membrane proton channel.; ATP synthase F0F1 subunit B 860340..860837 Streptococcus agalactiae 2603V/R 1013663 NP_687874.1 CDS atpH NC_004116.1 860837 861373 D Produces ATP from ADP in the presence of a proton gradient across the membrane; the delta subunit is part of the catalytic core of the ATP synthase complex; ATP synthase F0F1 subunit delta 860837..861373 Streptococcus agalactiae 2603V/R 1013664 NP_687875.1 CDS atpA NC_004116.1 861389 862894 D produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit; ATP synthase F0F1 subunit alpha 861389..862894 Streptococcus agalactiae 2603V/R 1013665 NP_687876.1 CDS atpG NC_004116.1 862910 863791 D Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is a regulatory subunit; ATP synthase F0F1 subunit gamma 862910..863791 Streptococcus agalactiae 2603V/R 1013666 NP_687877.1 CDS atpD NC_004116.1 863865 865271 D Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit; ATP synthase F0F1 subunit beta 863865..865271 Streptococcus agalactiae 2603V/R 1013667 NP_687878.1 CDS atpC NC_004116.1 865284 865697 D part of catalytic core of ATP synthase; alpha(3)beta(3)gamma(1)delta(1)epsilon(1); involved in producing ATP from ADP in the presence of the proton motive force across the membrane; ATP synthase F0F1 subunit epsilon 865284..865697 Streptococcus agalactiae 2603V/R 1013668 NP_687879.1 CDS SAG0865 NC_004116.1 865762 865992 D hypothetical protein 865762..865992 Streptococcus agalactiae 2603V/R 1013669 NP_687880.1 CDS murA-2 NC_004116.1 866055 867326 D adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active; UDP-N-acetylglucosamine 1-carboxyvinyltransferase 866055..867326 Streptococcus agalactiae 2603V/R 1013670 NP_687881.1 CDS SAG0867 NC_004116.1 867328 867519 D hypothetical protein 867328..867519 Streptococcus agalactiae 2603V/R 1013671 NP_687882.1 CDS endA NC_004116.1 867594 868451 D identified by match to PFAM protein family HMM PF01223; DNA-entry nuclease 867594..868451 Streptococcus agalactiae 2603V/R 1013672 NP_687883.1 CDS pheS NC_004116.1 868743 869783 D catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily; phenylalanyl-tRNA synthetase subunit alpha 868743..869783 Streptococcus agalactiae 2603V/R 1013673 NP_687884.1 CDS SAG0870 NC_004116.1 869866 870387 D identified by match to PFAM protein family HMM PF00583; acetyltransferase 869866..870387 Streptococcus agalactiae 2603V/R 1013674 NP_687885.1 CDS pheT NC_004116.1 870441 872846 D catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily; phenylalanyl-tRNA synthetase subunit beta 870441..872846 Streptococcus agalactiae 2603V/R 1013675 NP_687886.1 CDS SAG0872 NC_004116.1 872915 873817 R hypothetical protein complement(872915..873817) Streptococcus agalactiae 2603V/R 1013676 NP_687887.1 CDS rexB NC_004116.1 873995 877228 D similar to GP:2909715; identified by sequence similarity; RexAB system found in Gram positive bacteria appears to fulfill the biological roles of RecBCD found in Gram negative bacteria.; exonuclease RexB 873995..877228 Streptococcus agalactiae 2603V/R 1013677 NP_687888.1 CDS rexA NC_004116.1 877218 880841 D identified by match to PFAM protein family HMM PF00580; RexAB system found in Gram positive bacteria appears to fulfill the biological roles of RecBCD found in Gram negative bacteria.; exonuclease RexA 877218..880841 Streptococcus agalactiae 2603V/R 1013678 NP_687889.1 CDS SAG0875 NC_004116.1 880854 881771 D identified by match to PFAM protein family HMM PF01544; magnesium transporter CorA family protein 880854..881771 Streptococcus agalactiae 2603V/R 1013679 NP_687890.1 CDS trmE NC_004116.1 881804 883180 R in Escherichia coli this protein is involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2-thiouridine, which is found in the wobble position of some tRNAs and affects ribosomal frameshifting; shows potassium-dependent dimerization and GTP hydrolysis; also involved in regulation of glutamate-dependent acid resistance and activation of gadE; tRNA modification GTPase TrmE complement(881804..883180) Streptococcus agalactiae 2603V/R 1013680 NP_687891.1 CDS SAG0877 NC_004116.1 883308 885218 D identified by match to PFAM protein family HMM PF00005; ABC transporter ATP-binding protein 883308..885218 Streptococcus agalactiae 2603V/R 1013681 NP_687892.1 CDS SAG0878 NC_004116.1 885368 886336 D identified by match to PFAM protein family HMM PF00676; acetoin dehydrogenase, thymine PPi dependent, E1 component subunit alpha 885368..886336 Streptococcus agalactiae 2603V/R 1013682 NP_687893.1 CDS SAG0879 NC_004116.1 886411 887409 D identified by match to PFAM protein family HMM PF02779; acetoin dehydrogenase, thymine PPi dependent, E1 component subunit beta 886411..887409 Streptococcus agalactiae 2603V/R 1013683 NP_687894.1 CDS SAG0880 NC_004116.1 887536 888924 D Catalyzes the transfer of acetyl from acetyldihydrolipoamide to coenzyme A to form acetyl CoA; branched-chain alpha-keto acid dehydrogenase subunit E2 887536..888924 Streptococcus agalactiae 2603V/R 1013684 NP_687895.1 CDS SAG0881 NC_004116.1 888984 890741 D identified by match to PFAM protein family HMM PF00070; acetoin dehydrogenase, thymine PPi dependent, E3 component, dihydrolipoamide dehydrogenase 888984..890741 Streptococcus agalactiae 2603V/R 1013685 NP_687896.1 CDS lplA-1 NC_004116.1 890839 891828 D identified by match to PFAM protein family HMM PF02539; lipoate-protein ligase A 890839..891828 Streptococcus agalactiae 2603V/R 1013686 NP_687897.1 CDS SAG0883 NC_004116.1 891936 892721 R similar to OMNI:NTL01LL1120; identified by sequence similarity; cobyric acid synthase complement(891936..892721) Streptococcus agalactiae 2603V/R 1013687 NP_687898.1 CDS SAG0884 NC_004116.1 892721 894064 R mur ligase family protein complement(892721..894064) Streptococcus agalactiae 2603V/R 1013688 NP_687899.1 CDS SAG0885 NC_004116.1 894204 895055 D hypothetical protein 894204..895055 Streptococcus agalactiae 2603V/R 1013689 NP_687900.1 CDS SAG0886 NC_004116.1 895058 896017 D The product of this gene was detected by Western blot analysis. For details on the method see Tettelin et al. 2002.; hypothetical protein 895058..896017 Streptococcus agalactiae 2603V/R 1013690 NP_687901.1 CDS glmM NC_004116.1 896071 897423 D catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; phosphoglucosamine mutase 896071..897423 Streptococcus agalactiae 2603V/R 1013691 NP_687902.1 CDS SAG0888 NC_004116.1 897546 897917 D hypothetical protein 897546..897917 Streptococcus agalactiae 2603V/R 1013692 NP_687903.1 CDS SAG0889 NC_004116.1 897942 898322 D hypothetical protein 897942..898322 Streptococcus agalactiae 2603V/R 1013693 NP_687904.1 CDS SAG0890 NC_004116.1 898414 899544 D catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III; coproporphyrinogen III oxidase 898414..899544 Streptococcus agalactiae 2603V/R 1013694 NP_687905.1 CDS SAG0891 NC_004116.1 899548 900285 D hypothetical protein 899548..900285 Streptococcus agalactiae 2603V/R 1013695 NP_687906.1 CDS SAG0892 NC_004116.1 900286 901056 D identified by match to PFAM protein family HMM PF00702; HAD superfamily hydrolase 900286..901056 Streptococcus agalactiae 2603V/R 1013696 NP_687907.1 CDS SAG0893 NC_004116.1 901046 901702 D hypothetical protein 901046..901702 Streptococcus agalactiae 2603V/R 1013697 NP_687908.1 CDS SAG0894 NC_004116.1 902090 906202 D similar to OMNI:NTL01SPL0811; identified by sequence similarity; The product of this gene was detected by Western blot analysis. For details on the method see Tettelin et al. 2002.; hypothetical protein 902090..906202 Streptococcus agalactiae 2603V/R 1013698 NP_687909.1 CDS SAG0895 NC_004116.1 906204 907073 D lipoyl-binding domain-containing protein 906204..907073 Streptococcus agalactiae 2603V/R 1013699 NP_687910.1 CDS SAG0896 NC_004116.1 907085 907411 D similar to OMNI:NTL01SPL0813; identified by sequence similarity; oxidoreductase 907085..907411 Streptococcus agalactiae 2603V/R 1013700 NP_687911.1 CDS SAG0897 NC_004116.1 907398 908063 D hypothetical protein 907398..908063 Streptococcus agalactiae 2603V/R 1013701 NP_687912.1 CDS SAG0898 NC_004116.1 908175 908426 D hypothetical protein 908175..908426 Streptococcus agalactiae 2603V/R 1013702 NP_687913.1 CDS SAG0899 NC_004116.1 908439 908612 D hypothetical protein 908439..908612 Streptococcus agalactiae 2603V/R 1013703 NP_687914.1 CDS SAG0900 NC_004116.1 908847 909017 D hypothetical protein 908847..909017 Streptococcus agalactiae 2603V/R 1013704 NP_687915.1 CDS SAG0901 NC_004116.1 909099 909482 D hypothetical protein 909099..909482 Streptococcus agalactiae 2603V/R 1013705 NP_687916.1 CDS SAG0902 NC_004116.1 909460 909597 D hypothetical protein 909460..909597 Streptococcus agalactiae 2603V/R 1013706 NP_687917.1 CDS SAG0903 NC_004116.1 909601 909735 D hypothetical protein 909601..909735 Streptococcus agalactiae 2603V/R 1013707 NP_687918.1 CDS SAG0904 NC_004116.1 910104 910274 D hypothetical protein 910104..910274 Streptococcus agalactiae 2603V/R 1013708 NP_687919.1 CDS ndk NC_004116.1 910407 910823 D catalyzes the formation of nucleoside triphosphate from ATP and nucleoside diphosphate; nucleoside diphosphate kinase 910407..910823 Streptococcus agalactiae 2603V/R 1013709 NP_687920.1 CDS lepA NC_004116.1 910959 912791 D binds to the ribosome on the universally-conserved alpha-sarcin loop; GTP-binding protein LepA 910959..912791 Streptococcus agalactiae 2603V/R 1013710 NP_687921.1 CDS SAG0907 NC_004116.1 913038 915671 D identified by match to PFAM protein family HMM PF00560; The product of this gene was detected by Western blot analysis. For details on the method see Tettelin et al. 2002.; hypothetical protein 913038..915671 Streptococcus agalactiae 2603V/R 1013711 NP_687922.1 CDS SAG0908 NC_004116.1 915819 916430 D identified by match to PFAM protein family HMM PF01966; HD domain-containing protein 915819..916430 Streptococcus agalactiae 2603V/R 1013712 NP_687923.1 CDS SAG0909 NC_004116.1 916439 916903 D identified by match to PFAM protein family HMM PF00583; acetyltransferase 916439..916903 Streptococcus agalactiae 2603V/R 1013713 NP_687924.1 CDS SAG0910 NC_004116.1 916903 917337 D this stereospecific enzymes reduces the R isomer of methionine sulfoxide while MsrA reduces the S form; provides protection against oxidative stress; methionine sulfoxide reductase B 916903..917337 Streptococcus agalactiae 2603V/R 1013714 NP_687925.1 CDS SAG0911 NC_004116.1 917489 920281 D identified by match to PFAM protein family HMM PF00122; cation transporter E1-E2 family ATPase 917489..920281 Streptococcus agalactiae 2603V/R 1013715 NP_687926.1 CDS SAG0912 NC_004116.1 920281 921384 D hypothetical protein 920281..921384 Streptococcus agalactiae 2603V/R 1013716 NP_687927.1 CDS cat NC_004116.1 921505 922143 R identified by match to PFAM protein family HMM PF00132; chloramphenicol acetyltransferase complement(921505..922143) Streptococcus agalactiae 2603V/R 1013717 NP_687928.1 CDS SAG0914 NC_004116.1 922854 923465 D hypothetical protein 922854..923465 Streptococcus agalactiae 2603V/R 1013718 NP_687929.1 CDS SAG0915 NC_004116.1 923639 924856 R identified by match to PFAM protein family HMM PF00589; Tn916, transposase complement(923639..924856) Streptococcus agalactiae 2603V/R 1013719 NP_687930.1 CDS SAG0916 NC_004116.1 924938 925141 R similar to SP:P27452 GB:S56948 GB:X61025 PID:47462; identified by sequence similarity; Tn916, excisionase complement(924938..925141) Streptococcus agalactiae 2603V/R 1013720 NP_687931.1 CDS SAG0917 NC_004116.1 925125 925376 D Tn916 hypothetical protein 925125..925376 Streptococcus agalactiae 2603V/R 1013721 NP_687932.1 CDS SAG0918 NC_004116.1 925602 925832 R Tn916 hypothetical protein complement(925602..925832) Streptococcus agalactiae 2603V/R 1013722 NP_687933.1 CDS SAG0919 NC_004116.1 925829 926302 R Tn916 hypothetical protein complement(925829..926302) Streptococcus agalactiae 2603V/R 1013723 NP_687934.1 CDS SAG0920 NC_004116.1 926480 926551 R Tn916 hypothetical protein complement(926480..926551) Streptococcus agalactiae 2603V/R 1013724 NP_687935.1 CDS SAG0921 NC_004116.1 926756 927109 D identified by match to PFAM protein family HMM PF01381; Tn916, transcriptional regulator 926756..927109 Streptococcus agalactiae 2603V/R 1013725 NP_687936.1 CDS SAG0922 NC_004116.1 927169 927354 R Tn916 hypothetical protein complement(927169..927354) Streptococcus agalactiae 2603V/R 1013726 NP_687937.1 CDS tetM NC_004116.1 927455 929374 R identified by match to PFAM protein family HMM PF00009; tetracycline resistance protein complement(927455..929374) Streptococcus agalactiae 2603V/R 1013727 NP_687938.1 CDS SAG0924 NC_004116.1 929390 929476 R regulates the transcription of tet(M) by attenuation; tetracycline resistance determinant leader peptide complement(929390..929476) Streptococcus agalactiae 2603V/R 1013728 NP_687939.1 CDS SAG0925 NC_004116.1 929751 930683 R Tn916 hypothetical protein complement(929751..930683) Streptococcus agalactiae 2603V/R 1013729 NP_687940.1 CDS SAG0926 NC_004116.1 930680 931681 R identified by match to PFAM protein family HMM PF00877; Tn916, NLP/P60 family protein complement(930680..931681) Streptococcus agalactiae 2603V/R 1013730 NP_687941.1 CDS SAG0927 NC_004116.1 931678 933855 R hypothetical protein complement(931678..933855) Streptococcus agalactiae 2603V/R 1013731 NP_687942.1 CDS SAG0929 NC_004116.1 936288 936794 R Tn916 hypothetical protein complement(936288..936794) Streptococcus agalactiae 2603V/R 1013733 NP_687943.1 CDS SAG0930 NC_004116.1 936769 937266 R Tn916 hypothetical protein complement(936769..937266) Streptococcus agalactiae 2603V/R 1013734 NP_687944.1 CDS SAG0931 NC_004116.1 937383 937604 R Tn916 hypothetical protein complement(937383..937604) Streptococcus agalactiae 2603V/R 1013735 NP_687945.1 CDS SAG0932 NC_004116.1 937647 938852 R identified by match to PFAM protein family HMM PF01381; Tn916, transcriptional regulator complement(937647..938852) Streptococcus agalactiae 2603V/R 1013736 NP_687946.1 CDS SAG0933 NC_004116.1 939030 940415 R identified by match to PFAM protein family HMM PF01580; DNA translocase FtsK complement(939030..940415) Streptococcus agalactiae 2603V/R 1013737 NP_687947.1 CDS SAG0934 NC_004116.1 940444 940830 R Tn916 hypothetical protein complement(940444..940830) Streptococcus agalactiae 2603V/R 1013738 NP_687948.1 CDS SAG0935 NC_004116.1 940846 941160 R Tn916 hypothetical protein complement(940846..941160) Streptococcus agalactiae 2603V/R 1013739 NP_687949.1 CDS SAG0936 NC_004116.1 941183 941302 R Tn916 hypothetical protein complement(941183..941302) Streptococcus agalactiae 2603V/R 1013740 NP_687950.1 CDS SAG0938 NC_004116.1 943034 943402 R identified by match to PFAM protein family HMM PF00392; GntR family transcriptional regulator complement(943034..943402) Streptococcus agalactiae 2603V/R 1013742 NP_687951.1 CDS dnaE NC_004116.1 943547 946651 D Catalyzes DNA-template-directed extension of the 3'-end of a DNA strand by one nucleotide at a time. Proposed to be responsible for the synthesis of the lagging strand. In the low GC gram positive bacteria this enzyme is less processive and more error prone than its counterpart in other bacteria.; DNA polymerase III DnaE 943547..946651 Streptococcus agalactiae 2603V/R 1013743 NP_687952.1 CDS pfkA NC_004116.1 946732 947754 D catalyzes the formation of D-fructose 1,6-bisphosphate from D-fructose 6-phosphate in glycolysis; 6-phosphofructokinase 946732..947754 Streptococcus agalactiae 2603V/R 1013744 NP_687953.1 CDS pyk NC_004116.1 947803 949305 D catalyzes the formation of phosphoenolpyruvate from pyruvate; pyruvate kinase 947803..949305 Streptococcus agalactiae 2603V/R 1013745 NP_687954.1 CDS SAG0942 NC_004116.1 949476 950033 D identified by match to PFAM protein family HMM PF00461; signal peptidase I 949476..950033 Streptococcus agalactiae 2603V/R 1013746 NP_687955.1 CDS SAG0943 NC_004116.1 950047 950190 R hypothetical protein complement(950047..950190) Streptococcus agalactiae 2603V/R 1013747 NP_687956.1 CDS glmS NC_004116.1 950302 952116 D Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source; glucosamine--fructose-6-phosphate aminotransferase 950302..952116 Streptococcus agalactiae 2603V/R 1013748 NP_687957.1 CDS SAG0945 NC_004116.1 952293 953426 D identified by match to PFAM protein family HMM PF01609; IS1548 transposase 952293..953426 Streptococcus agalactiae 2603V/R 1013749 NP_687958.1 CDS phnA NC_004116.1 953605 953934 D identified by match to TIGR protein family HMM TIGR00686; phnA protein 953605..953934 Streptococcus agalactiae 2603V/R 1013750 NP_687959.1 CDS SAG0947 NC_004116.1 954069 954710 D identified by match to PFAM protein family HMM PF00528; amino acid ABC transporter permease 954069..954710 Streptococcus agalactiae 2603V/R 1013751 NP_687960.1 CDS SAG0948 NC_004116.1 954720 955349 D identified by match to PFAM protein family HMM PF00005; amino acid ABC transporter ATP-binding protein 954720..955349 Streptococcus agalactiae 2603V/R 1013752 NP_687961.1 CDS SAG0949 NC_004116.1 955366 956196 D identified by match to PFAM protein family HMM PF00497; amino acid ABC transporter amino acid-binding protein 955366..956196 Streptococcus agalactiae 2603V/R 1013753 NP_687962.2 CDS rpsT NC_004116.1 956280 956513 R binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase; 30S ribosomal protein S20 complement(956280..956513) Streptococcus agalactiae 2603V/R 1013754 NP_687963.1 CDS coaA NC_004116.1 956582 957502 R catalyzes the formation of (R)-4'-phosphopantothenate in coenzyme A biosynthesis; pantothenate kinase complement(956582..957502) Streptococcus agalactiae 2603V/R 1013755 NP_687964.1 CDS SAG0952 NC_004116.1 957608 958198 D hypothetical protein 957608..958198 Streptococcus agalactiae 2603V/R 1013756 NP_687965.1 CDS cdd NC_004116.1 958524 958913 D Reclaims exogenous and endogenous cytidine and 2'-deoxycytidine molecules for UMP synthesis; cytidine deaminase 958524..958913 Streptococcus agalactiae 2603V/R 1013757 NP_687966.1 CDS SAG0954 NC_004116.1 958978 960027 D identified by match to PFAM protein family HMM PF02608; The product of this gene was detected by Western blot analysis. For details on the method see Tettelin et al. 2002.; hypothetical protein 958978..960027 Streptococcus agalactiae 2603V/R 1013758 NP_687967.1 CDS SAG0955 NC_004116.1 960172 961707 D identified by match to PFAM protein family HMM PF00005; sugar ABC transporter ATP-binding protein 960172..961707 Streptococcus agalactiae 2603V/R 1013759 NP_687968.1 CDS SAG0956 NC_004116.1 961700 962761 D sugar ABC transporter permease 961700..962761 Streptococcus agalactiae 2603V/R 1013760 NP_687969.1 CDS SAG0957 NC_004116.1 962763 963719 D sugar ABC transporter permease 962763..963719 Streptococcus agalactiae 2603V/R 1013761 NP_687970.1 CDS nox-2 NC_004116.1 963924 965294 D identified by match to PFAM protein family HMM PF00070; NADH oxidase 963924..965294 Streptococcus agalactiae 2603V/R 1013762 NP_687971.1 CDS ldh NC_004116.1 965415 966404 R Converts (S)-lactate and NAD(+) to pyruvate and NADH; L-lactate dehydrogenase complement(965415..966404) Streptococcus agalactiae 2603V/R 1013763 NP_687972.1 CDS gyrA NC_004116.1 966643 969102 D negatively supercoils closed circular double-stranded DNA; DNA gyrase subunit A 966643..969102 Streptococcus agalactiae 2603V/R 1013764 NP_687973.1 CDS srtA NC_004116.1 969109 969852 D identified by match to TIGR protein family HMM TIGR01076; sortase SrtA 969109..969852 Streptococcus agalactiae 2603V/R 1013765 NP_687974.1 CDS SAG0962 NC_004116.1 969868 970281 D identified by match to PFAM protein family HMM PF00903; glyoxylase 969868..970281 Streptococcus agalactiae 2603V/R 1013766 NP_687975.1 CDS SAG0963 NC_004116.1 970434 971396 D hypothetical protein 970434..971396 Streptococcus agalactiae 2603V/R 1013767 NP_687976.1 CDS SAG0964 NC_004116.1 971459 972586 R identified by match to PFAM protein family HMM PF00999; Na+/H+ exchanger family protein complement(971459..972586) Streptococcus agalactiae 2603V/R 1013768 NP_687977.1 CDS SAG0965 NC_004116.1 972846 973229 D similar to OMNI:SP0537; identified by sequence similarity; IS1381 transposase protein A 972846..973229 Streptococcus agalactiae 2603V/R 1013769 NP_687978.1 CDS SAG0966 NC_004116.1 973262 973651 D identified by match to PFAM protein family HMM PF01609; IS1381 transposase protein B 973262..973651 Streptococcus agalactiae 2603V/R 1013770 NP_687979.1 CDS guaA NC_004116.1 973717 975279 R contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway; GMP synthase complement(973717..975279) Streptococcus agalactiae 2603V/R 1013771 NP_687980.1 CDS SAG0968 NC_004116.1 975492 976190 D identified by match to PFAM protein family HMM PF00392; GntR family transcriptional regulator 975492..976190 Streptococcus agalactiae 2603V/R 1013772 NP_687981.1 CDS gid NC_004116.1 976304 977638 D TrmFO; Gid; glucose-inhibited division protein; similar to GidA; the gene from Bacillus subtilis encodes a tRNA-methyltransferase that utilizes folate as the carbon donor and bound flavin as reductant; modifies tRNA at position 54 (uridine) of the T-psi loop to form a C5-methyluridine; tRNA (uracil-5-)-methyltransferase Gid 976304..977638 Streptococcus agalactiae 2603V/R 1013773 NP_687982.1 CDS SAG0970 NC_004116.1 977716 978459 D identified by match to PFAM protein family HMM PF00583; acetyltransferase 977716..978459 Streptococcus agalactiae 2603V/R 1013774 NP_687983.1 CDS SAG0971 NC_004116.1 978592 979440 D identified by match to PFAM protein family HMM PF03180; The product of this gene was detected by Western blot analysis. For details on the method see Tettelin et al. 2002.; hypothetical protein 978592..979440 Streptococcus agalactiae 2603V/R 1013775 NP_687984.1 CDS SAG0973 NC_004116.1 980127 981089 D nisin-resistance protein 980127..981089 Streptococcus agalactiae 2603V/R 1013777 NP_687985.1 CDS SAG0974 NC_004116.1 981115 981867 D identified by match to PFAM protein family HMM PF00005; ABC transporter ATP-binding protein 981115..981867 Streptococcus agalactiae 2603V/R 1013778 NP_687986.1 CDS SAG0975 NC_004116.1 981869 983824 D similar to OMNI:NTL01LL1789; identified by sequence similarity; ABC transporter permease 981869..983824 Streptococcus agalactiae 2603V/R 1013779 NP_687987.1 CDS SAG0976 NC_004116.1 983934 984602 D identified by match to PFAM protein family HMM PF00072; DNA-binding response regulator 983934..984602 Streptococcus agalactiae 2603V/R 1013780 NP_687988.1 CDS SAG0977 NC_004116.1 984599 985537 D identified by match to PFAM protein family HMM PF00512; sensor histidine kinase 984599..985537 Streptococcus agalactiae 2603V/R 1013781 NP_687989.1 CDS xerS NC_004116.1 985580 986650 R site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; cell division protein FtsK may regulate the XerS; site-specific tyrosine recombinase XerS complement(985580..986650) Streptococcus agalactiae 2603V/R 1013782 NP_687990.1 CDS SAG0979 NC_004116.1 987103 988764 D identified by match to PFAM protein family HMM PF00496; ABC transporter substrate-binding protein 987103..988764 Streptococcus agalactiae 2603V/R 1013783 NP_687991.1 CDS SAG0980 NC_004116.1 988797 989570 R hypothetical protein complement(988797..989570) Streptococcus agalactiae 2603V/R 1013784 NP_687992.1 CDS SAG0981 NC_004116.1 989560 990246 R similar to GP:11055964; identified by sequence similarity; satD protein complement(989560..990246) Streptococcus agalactiae 2603V/R 1013785 NP_687993.1 CDS ffh NC_004116.1 990313 991878 R identified by match to PFAM protein family HMM PF00448; signal recognition particle protein Ffh complement(990313..991878) Streptococcus agalactiae 2603V/R 1013786 NP_687994.1 CDS SAG0983 NC_004116.1 991896 992228 R DNA-binding protein complement(991896..992228) Streptococcus agalactiae 2603V/R 1013787 NP_687995.1 CDS SAG0984 NC_004116.1 992317 993630 R identified by match to PFAM protein family HMM PF00512; sensor histidine kinase CiaH complement(992317..993630) Streptococcus agalactiae 2603V/R 1013788 NP_687996.1 CDS ciaR NC_004116.1 993614 994294 R identified by match to PFAM protein family HMM PF00072; DNA-binding response regulator CiaR complement(993614..994294) Streptococcus agalactiae 2603V/R 1013789 NP_687997.1 CDS pepN NC_004116.1 994456 997005 R identified by match to PFAM protein family HMM PF01433; aminopeptidase complement(994456..997005) Streptococcus agalactiae 2603V/R 1013790 NP_687998.1 CDS phoU NC_004116.1 997151 997804 R identified by match to PFAM protein family HMM PF01895; phosphate transport system regulatory protein PhoU complement(997151..997804) Streptococcus agalactiae 2603V/R 1013791 NP_687999.1 CDS SAG0988 NC_004116.1 997838 998596 R ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation; phosphate transporter ATP-binding protein complement(997838..998596) Streptococcus agalactiae 2603V/R 1013792 NP_688000.1 CDS SAG0989 NC_004116.1 998608 999411 R ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation; phosphate transporter ATP-binding protein complement(998608..999411) Streptococcus agalactiae 2603V/R 1013793 NP_688001.1 CDS SAG0990 NC_004116.1 999423 1000310 R identified by match to PFAM protein family HMM PF00528; phosphate ABC transporter permease complement(999423..1000310) Streptococcus agalactiae 2603V/R 1013794 NP_688002.1 CDS SAG0991 NC_004116.1 1000300 1001217 R identified by match to PFAM protein family HMM PF00528; phosphate ABC transporter permease complement(1000300..1001217) Streptococcus agalactiae 2603V/R 1013795 NP_688003.1 CDS SAG0992 NC_004116.1 1001263 1002123 R identified by match to PFAM protein family HMM PF01449; phosphate ABC transporter substrate-binding protein complement(1001263..1002123) Streptococcus agalactiae 2603V/R 1013796 NP_688004.1 CDS SAG0993 NC_004116.1 1002308 1003618 R identified by match to PFAM protein family HMM PF01189; NOL1/NOP2/sun family protein complement(1002308..1003618) Streptococcus agalactiae 2603V/R 1013797 NP_688005.1 CDS SAG0994 NC_004116.1 1003686 1004450 R identified by match to PFAM protein family HMM PF00459; inositol monophosphatase complement(1003686..1004450) Streptococcus agalactiae 2603V/R 1013798 NP_688006.1 CDS SAG0995 NC_004116.1 1004440 1004721 R hypothetical protein complement(1004440..1004721) Streptococcus agalactiae 2603V/R 1013799 NP_688007.1 CDS spxA NC_004116.1 1004714 1005127 R the anti-alpha factor Spx interacts with RNA polymerase alpha subunit C-terminal domain in a region that interacts with the sigma 70 subunit and may interfere with activation of promoters; in Bacillus subtilis this protein is a substrate for ClpXP protease; blocks transcription of the competence regulatory gene encoded by the srf operon; regulates a number of genes involved in thiol homeostasis including trxA and trxB; monomeric member of ArsC family of proteins; does not bind DNA; contains a disulfide bond between C10 and C13 which may sense disulfide stress; Spx family transcriptional regulator complement(1004714..1005127) Streptococcus agalactiae 2603V/R 1013800 NP_688008.1 CDS SAG0997 NC_004116.1 1005170 1006102 R catalyzes the formation of FMN from riboflavin and the formation of FAD from FMN; in Bacillus the ribC gene has both flavokinase and FAD synthetase activities; bifunctional riboflavin kinase/FMN adenylyltransferase complement(1005170..1006102) Streptococcus agalactiae 2603V/R 1013801 NP_688009.1 CDS truB NC_004116.1 1006115 1006999 R catalyzes isomerization of specific uridines in RNA to pseudouridine; responsible for residues in T loops of many tRNAs; tRNA pseudouridine synthase B complement(1006115..1006999) Streptococcus agalactiae 2603V/R 1013802 NP_688010.1 CDS SAG0999 NC_004116.1 1007091 1007522 R identified by match to PFAM protein family HMM PF00583; acetyltransferase complement(1007091..1007522) Streptococcus agalactiae 2603V/R 1013803 NP_688011.1 CDS SAG1000 NC_004116.1 1007535 1008806 R hypothetical protein complement(1007535..1008806) Streptococcus agalactiae 2603V/R 1013804 NP_688012.1 CDS SAG1001 NC_004116.1 1008840 1009430 R hypothetical protein complement(1008840..1009430) Streptococcus agalactiae 2603V/R 1013805 NP_688013.1 CDS SAG1002 NC_004116.1 1009537 1010415 R identified by match to PFAM protein family HMM PF02517; protease complement(1009537..1010415) Streptococcus agalactiae 2603V/R 1013806 NP_688014.1 CDS SAG1003 NC_004116.1 1010521 1013151 R identified by match to PFAM protein family HMM PF02687; permease complement(1010521..1013151) Streptococcus agalactiae 2603V/R 1013807 NP_688015.1 CDS SAG1004 NC_004116.1 1013163 1013864 R identified by match to PFAM protein family HMM PF00005; ABC transporter ATP-binding protein complement(1013163..1013864) Streptococcus agalactiae 2603V/R 1013808 NP_688016.1 CDS topA NC_004116.1 1014001 1016121 R catalyzes the ATP-dependent breakage of single-stranded DNA followed by passage and rejoining, maintains net negative superhelicity; DNA topoisomerase I complement(1014001..1016121) Streptococcus agalactiae 2603V/R 1013809 NP_688017.1 CDS dprA NC_004116.1 1016216 1017058 R identified by match to PFAM protein family HMM PF02481; DprA/SMF protein DNA processing factor complement(1016216..1017058) Streptococcus agalactiae 2603V/R 1013810 NP_688018.1 CDS SAG1007 NC_004116.1 1017196 1018224 R identified by match to PFAM protein family HMM PF01497; iron-compound ABC transporter iron-compound-binding protein complement(1017196..1018224) Streptococcus agalactiae 2603V/R 1013811 NP_688019.1 CDS SAG1008 NC_004116.1 1018286 1019047 R identified by match to PFAM protein family HMM PF00005; iron ABC transporter ATP-binding protein complement(1018286..1019047) Streptococcus agalactiae 2603V/R 1013812 NP_688020.1 CDS SAG1009 NC_004116.1 1019044 1020018 R identified by match to PFAM protein family HMM PF01032; iron ABC transporter permease complement(1019044..1020018) Streptococcus agalactiae 2603V/R 1013813 NP_688021.1 CDS SAG1010 NC_004116.1 1020015 1020977 R identified by match to PFAM protein family HMM PF01032; iron ABC transporter permease complement(1020015..1020977) Streptococcus agalactiae 2603V/R 1013814 NP_688022.1 CDS SAG1011 NC_004116.1 1021216 1021764 R identified by match to PFAM protein family HMM PF00132; acetyltransferase complement(1021216..1021764) Streptococcus agalactiae 2603V/R 1013815 NP_688023.1 CDS rnhB NC_004116.1 1021785 1022546 R RNH2; RNase HII; binds manganese; endonuclease which specifically degrades the RNA of RNA-DNA hybrids; ribonuclease HII complement(1021785..1022546) Streptococcus agalactiae 2603V/R 1013816 NP_688024.1 CDS rbgA NC_004116.1 1022533 1023384 R essential GTPase; functions in ribosome assembly; binds a unique part of the 23S rRNA; interacts with ribosomal protein L25(Ctc); ribosomal biogenesis GTPase complement(1022533..1023384) Streptococcus agalactiae 2603V/R 1013817 NP_688025.1 CDS SAG1014 NC_004116.1 1023660 1024232 R identified by Glimmer2; The product of this gene was detected by Western blot analysis. For details on the method see Tettelin et al. 2002.; hypothetical protein complement(1023660..1024232) Streptococcus agalactiae 2603V/R 1013818 NP_688026.1 CDS SAG1015 NC_004116.1 1024433 1025917 R carbon starvation protein CstA complement(1024433..1025917) Streptococcus agalactiae 2603V/R 1013819 NP_688027.1 CDS SAG1016 NC_004116.1 1026073 1026807 R identified by match to PFAM protein family HMM PF00072; response regulator complement(1026073..1026807) Streptococcus agalactiae 2603V/R 1013820 NP_688028.1 CDS SAG1017 NC_004116.1 1026819 1028558 R identified by match to PFAM protein family HMM PF02518; sensor histidine kinase complement(1026819..1028558) Streptococcus agalactiae 2603V/R 1013821 NP_688029.1 CDS SAG1018 NC_004116.1 1029094 1029216 R lipoprotein complement(1029094..1029216) Streptococcus agalactiae 2603V/R 1013822 NP_688030.1 CDS SAG1019 NC_004116.1 1029739 1029858 R hypothetical protein complement(1029739..1029858) Streptococcus agalactiae 2603V/R 1013823 NP_688031.1 CDS SAG1020 NC_004116.1 1030102 1030785 R lipoprotein complement(1030102..1030785) Streptococcus agalactiae 2603V/R 1013824 NP_688032.1 CDS SAG1021 NC_004116.1 1030871 1031194 R hypothetical protein complement(1030871..1031194) Streptococcus agalactiae 2603V/R 1013825 NP_688033.1 CDS SAG1022 NC_004116.1 1031542 1032075 R hypothetical protein complement(1031542..1032075) Streptococcus agalactiae 2603V/R 1013826 NP_688034.1 CDS SAG1023 NC_004116.1 1032087 1032233 R hypothetical protein complement(1032087..1032233) Streptococcus agalactiae 2603V/R 1013827 NP_688035.1 CDS SAG1024 NC_004116.1 1032230 1032781 R lipoprotein complement(1032230..1032781) Streptococcus agalactiae 2603V/R 1013828 NP_688036.1 CDS SAG1025 NC_004116.1 1032786 1033235 R hypothetical protein complement(1032786..1033235) Streptococcus agalactiae 2603V/R 1013829 NP_688037.1 CDS SAG1027 NC_004116.1 1035253 1035507 R hypothetical protein complement(1035253..1035507) Streptococcus agalactiae 2603V/R 1013831 NP_688038.1 CDS SAG1028 NC_004116.1 1035528 1036118 R hypothetical protein complement(1035528..1036118) Streptococcus agalactiae 2603V/R 1013832 NP_688039.1 CDS SAG1029 NC_004116.1 1036132 1036437 R hypothetical protein complement(1036132..1036437) Streptococcus agalactiae 2603V/R 1013833 NP_688040.1 CDS SAG1030 NC_004116.1 1036566 1037480 R similar to OMNI:SA0643; identified by sequence similarity; The product of this gene was detected by Western blot analysis. For details on the method see Tettelin et al. 2002.; hypothetical protein complement(1036566..1037480) Streptococcus agalactiae 2603V/R 1013834 NP_688041.1 CDS SAG1031 NC_004116.1 1037483 1037845 R similar to GB:L13925 PID:466482; identified by sequence similarity; hypothetical protein complement(1037483..1037845) Streptococcus agalactiae 2603V/R 1013835 NP_688042.1 CDS SAG1032 NC_004116.1 1037950 1038207 R hypothetical protein complement(1037950..1038207) Streptococcus agalactiae 2603V/R 1013836 NP_688043.1 CDS SAG1033 NC_004116.1 1038221 1042150 R identified by match to PFAM protein family HMM PF01580; DNA translocase FtsK complement(1038221..1042150) Streptococcus agalactiae 2603V/R 1013837 NP_688044.1 CDS SAG1034 NC_004116.1 1042461 1042628 R hypothetical protein complement(1042461..1042628) Streptococcus agalactiae 2603V/R 1013838 NP_688045.1 CDS SAG1035 NC_004116.1 1042635 1043909 R hypothetical protein complement(1042635..1043909) Streptococcus agalactiae 2603V/R 1013839 NP_688046.1 CDS SAG1036 NC_004116.1 1043909 1044151 R hypothetical protein complement(1043909..1044151) Streptococcus agalactiae 2603V/R 1013840 NP_688047.1 CDS SAG1037 NC_004116.1 1044135 1044608 R hypothetical protein complement(1044135..1044608) Streptococcus agalactiae 2603V/R 1013841 NP_688048.1 CDS SAG1038 NC_004116.1 1044617 1047628 R phage infection protein complement(1044617..1047628) Streptococcus agalactiae 2603V/R 1013842 NP_688049.1 CDS SAG1039 NC_004116.1 1047710 1048000 R hypothetical protein complement(1047710..1048000) Streptococcus agalactiae 2603V/R 1013843 NP_688050.1 CDS SAG1040 NC_004116.1 1048117 1048899 R similar to GP:14588952; identified by sequence similarity; hypothetical protein complement(1048117..1048899) Streptococcus agalactiae 2603V/R 1013844 NP_688051.1 CDS SAG1041 NC_004116.1 1048896 1049219 R hypothetical protein complement(1048896..1049219) Streptococcus agalactiae 2603V/R 1013845 NP_688052.1 CDS carB NC_004116.1 1049346 1052528 R four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate; CarB is responsible for the amidotransferase activity; carbamoyl phosphate synthase large subunit complement(1049346..1052528) Streptococcus agalactiae 2603V/R 1013846 NP_688053.1 CDS carA-1 NC_004116.1 1052559 1053635 R catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers; carbamoyl phosphate synthase small subunit complement(1052559..1053635) Streptococcus agalactiae 2603V/R 1013847 NP_688054.1 CDS pyrB NC_004116.1 1053649 1054572 R catalyzes the transfer of the carbamoyl moiety from carbamoyl phosphate to L- aspartate in pyrimidine biosynthesis; aspartate carbamoyltransferase complement(1053649..1054572) Streptococcus agalactiae 2603V/R 1013848 NP_688055.1 CDS pyrC NC_004116.1 1054737 1056029 R catalyzes the formation of N-carbamoyl-L-aspartate from (S)-dihydroorotate in pyrimidine biosynthesis; dihydroorotase complement(1054737..1056029) Streptococcus agalactiae 2603V/R 1013849 NP_688056.1 CDS pyrE NC_004116.1 1056041 1056670 R involved in fifth step of pyrimidine biosynthesis; converts orotidine 5'-phosphate and diphosphate to orotate and 5-phospho-alpha-D-ribose 1-diphosphate; orotate phosphoribosyltransferase complement(1056041..1056670) Streptococcus agalactiae 2603V/R 1013850 NP_688057.1 CDS pyrF NC_004116.1 1056683 1057384 R OMP decarboxylase; OMPDCase; OMPdecase; type 1 subfamily; involved in last step of pyrimidine biosynthesis; converts orotidine 5'-phosphate to UMP and carbon dioxide; OMP decarboxylase; OMPDCase; OMPdecase; orotidine 5'-phosphate decarboxylase complement(1056683..1057384) Streptococcus agalactiae 2603V/R 1013851 NP_688058.1 CDS SAG1048 NC_004116.1 1057597 1058829 R similar to OMNI:NTL01CA2266; identified by sequence similarity; hypothetical protein complement(1057597..1058829) Streptococcus agalactiae 2603V/R 1013852 NP_688059.1 CDS SAG1049 NC_004116.1 1058869 1060410 R identified by match to PFAM protein family HMM PF00005; ABC transporter ATP-binding protein complement(1058869..1060410) Streptococcus agalactiae 2603V/R 1013853 NP_688060.1 CDS asd NC_004116.1 1061049 1062125 R catalyzes the formation of 4-aspartyl phosphate from aspartate 4-semialdehyde; aspartate-semialdehyde dehydrogenase complement(1061049..1062125) Streptococcus agalactiae 2603V/R 1013855 NP_688061.1 CDS SAG1052 NC_004116.1 1062335 1062478 R cell wall surface anchor family protein complement(1062335..1062478) Streptococcus agalactiae 2603V/R 1013856 NP_688062.1 CDS SAG1053 NC_004116.1 1063089 1063181 D hypothetical protein 1063089..1063181 Streptococcus agalactiae 2603V/R 1013857 NP_688063.2 CDS cls NC_004116.1 1063395 1064870 R identified by match to PFAM protein family HMM PF00614; cardiolipin synthetase complement(1063395..1064870) Streptococcus agalactiae 2603V/R 1013858 NP_688064.1 CDS fhs NC_004116.1 1065109 1066779 R catalyzes the formation of 10-formyltetrahydrofolate from formate and tetrahydrofolate; formate--tetrahydrofolate ligase complement(1065109..1066779) Streptococcus agalactiae 2603V/R 1013859 NP_688065.1 CDS lplA-2 NC_004116.1 1066868 1067887 R identified by match to PFAM protein family HMM PF02539; lipoate-protein ligase A complement(1066868..1067887) Streptococcus agalactiae 2603V/R 1013860 NP_688066.1 CDS SAG1057 NC_004116.1 1067914 1068792 R hypothetical protein complement(1067914..1068792) Streptococcus agalactiae 2603V/R 1013861 NP_688067.1 CDS SAG1058 NC_004116.1 1068761 1069579 R hypothetical protein complement(1068761..1069579) Streptococcus agalactiae 2603V/R 1013862 NP_688068.1 CDS SAG1059 NC_004116.1 1069572 1069904 R identified by match to PFAM protein family HMM PF01597; glycine cleavage system H protein complement(1069572..1069904) Streptococcus agalactiae 2603V/R 1013863 NP_688069.1 CDS SAG1060 NC_004116.1 1069933 1070919 R identified by match to PFAM protein family HMM PF00296; luciferase family protein complement(1069933..1070919) Streptococcus agalactiae 2603V/R 1013864 NP_688070.1 CDS SAG1061 NC_004116.1 1070916 1072115 R identified by match to PFAM protein family HMM PF00724; oxidoreductase, FMN-binding complement(1070916..1072115) Streptococcus agalactiae 2603V/R 1013865 NP_688071.1 CDS SAG1062 NC_004116.1 1072108 1072956 R hypothetical protein complement(1072108..1072956) Streptococcus agalactiae 2603V/R 1013866 NP_688072.1 CDS SAG1063 NC_004116.1 1073098 1073784 D similar to GB:L77117 PID:1591587; identified by sequence similarity; phosphopantothenate--cysteine ligase 1073098..1073784 Streptococcus agalactiae 2603V/R 1013867 NP_688073.1 CDS SAG1064 NC_004116.1 1073777 1074319 D decarboxylates 4-phosphopantothenoylcysteine to form 4'-phosphopantotheine.; phosphopantothenoylcysteine decarboxylase 1073777..1074319 Streptococcus agalactiae 2603V/R 1013868 NP_688074.1 CDS SAG1065 NC_004116.1 1074365 1074937 D similar to OMNI:NTL01SPL0962; identified by sequence similarity; hypothetical protein 1074365..1074937 Streptococcus agalactiae 2603V/R 1013869 NP_688075.1 CDS pgm NC_004116.1 1075047 1076765 D identified by match to PFAM protein family HMM PF00408; phosphoglucomutase 1075047..1076765 Streptococcus agalactiae 2603V/R 1013870 NP_688076.1 CDS SAG1067 NC_004116.1 1076837 1077373 D IS861, transposase OrfA 1076837..1077373 Streptococcus agalactiae 2603V/R 1013871 NP_688077.1 CDS SAG1068 NC_004116.1 1077349 1078182 D identified by match to PFAM protein family HMM PF00665; IS861, transposase OrfB 1077349..1078182 Streptococcus agalactiae 2603V/R 1013872 NP_688078.1 CDS SAG1069 NC_004116.1 1078264 1078461 R hypothetical protein complement(1078264..1078461) Streptococcus agalactiae 2603V/R 1013873 NP_688079.1 CDS SAG1070 NC_004116.1 1078475 1080208 R identified by match to PFAM protein family HMM PF00005; ABC transporter ATP-binding protein/permease complement(1078475..1080208) Streptococcus agalactiae 2603V/R 1013874 NP_688080.1 CDS SAG1071 NC_004116.1 1080209 1081930 R identified by match to PFAM protein family HMM PF00005; ABC transporter ATP-binding protein/permease complement(1080209..1081930) Streptococcus agalactiae 2603V/R 1013875 NP_688081.1 CDS SAG1072 NC_004116.1 1081942 1082544 R hypothetical protein complement(1081942..1082544) Streptococcus agalactiae 2603V/R 1013876 NP_688082.1 CDS SAG1073 NC_004116.1 1082546 1083523 R hypothetical protein complement(1082546..1083523) Streptococcus agalactiae 2603V/R 1013877 NP_688083.1 CDS glyA NC_004116.1 1083528 1084784 R catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate; serine hydroxymethyltransferase complement(1083528..1084784) Streptococcus agalactiae 2603V/R 1013878 NP_688084.1 CDS SAG1075 NC_004116.1 1084876 1085427 R identified by match to PFAM protein family HMM PF01300; Sua5/YciO/YrdC/YwlC family protein complement(1084876..1085427) Streptococcus agalactiae 2603V/R 1013879 NP_688085.1 CDS SAG1076 NC_004116.1 1085465 1086295 R identified by match to TIGR protein family HMM TIGR00536; HemK family modification methylase complement(1085465..1086295) Streptococcus agalactiae 2603V/R 1013880 NP_688086.1 CDS prfA NC_004116.1 1086295 1087374 R recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2; peptide chain release factor 1 complement(1086295..1087374) Streptococcus agalactiae 2603V/R 1013881 NP_688087.1 CDS tdk NC_004116.1 1087409 1087978 R catalyzes the formation of thymidine 5'-phosphate from thymidine; thymidine kinase complement(1087409..1087978) Streptococcus agalactiae 2603V/R 1013882 NP_688088.1 CDS xylM NC_004116.1 1088116 1088298 D 4-OT; member of subfamily 5; forms a dimer; the function in the Escherichia coli cell is unknown; 4-oxalocrotonate tautomerase 1088116..1088298 Streptococcus agalactiae 2603V/R 1013883 NP_688089.1 CDS SAG1080 NC_004116.1 1088274 1088417 R hypothetical protein complement(1088274..1088417) Streptococcus agalactiae 2603V/R 1013884 NP_688090.1 CDS SAG1081 NC_004116.1 1088447 1089385 D identified by match to PFAM protein family HMM PF02424; ApbE family protein 1088447..1089385 Streptococcus agalactiae 2603V/R 1013885 NP_688091.1 CDS SAG1082 NC_004116.1 1089403 1090005 D hypothetical protein 1089403..1090005 Streptococcus agalactiae 2603V/R 1013886 NP_688092.1 CDS SAG1083 NC_004116.1 1090029 1091264 D hypothetical protein 1090029..1091264 Streptococcus agalactiae 2603V/R 1013887 NP_688093.1 CDS SAG1084 NC_004116.1 1091363 1092151 D identified by match to PFAM protein family HMM PF01226; formate/nitrite transporter family protein 1091363..1092151 Streptococcus agalactiae 2603V/R 1013888 NP_688094.1 CDS pbuX NC_004116.1 1092250 1093524 R identified by match to PFAM protein family HMM PF00860; xanthine permease complement(1092250..1093524) Streptococcus agalactiae 2603V/R 1013889 NP_688095.1 CDS xpt NC_004116.1 1093524 1094105 R Catalyzes the transfer of the phosphoribosyl moiety from 5-phospho--D-ribosyl-1-pyrophosphate (PRib-PP) to the 6-oxo-guanine and -xanthine; xanthine phosphoribosyltransferase complement(1093524..1094105) Streptococcus agalactiae 2603V/R 1013890 NP_688096.1 CDS guaC NC_004116.1 1094361 1095344 R identified by match to PFAM protein family HMM PF00478; guanosine 5'-monophosphate oxidoreductase complement(1094361..1095344) Streptococcus agalactiae 2603V/R 1013891 NP_688097.1 CDS SAG1088 NC_004116.1 1095548 1096888 R EmrB/QacA family drug resistance transporter complement(1095548..1096888) Streptococcus agalactiae 2603V/R 1013892 NP_688098.1 CDS SAG1089 NC_004116.1 1097159 1097851 D hypothetical protein 1097159..1097851 Streptococcus agalactiae 2603V/R 1013893 NP_688099.1 CDS SAG1090 NC_004116.1 1097922 1099922 R identified by match to PFAM protein family HMM PF02705; potassium uptake protein complement(1097922..1099922) Streptococcus agalactiae 2603V/R 1013894 NP_688100.1 CDS SAG1091 NC_004116.1 1100057 1100707 R identified by match to PFAM protein family HMM PF00106; short chain dehydrogenase/reductase family oxidoreductase complement(1100057..1100707) Streptococcus agalactiae 2603V/R 1013895 NP_688101.1 CDS eutD NC_004116.1 1100881 1101873 R in Salmonella this enzyme is required for ethanolamine catabolism; has higher affinity for CoA than Pta; phosphotransacetylase complement(1100881..1101873) Streptococcus agalactiae 2603V/R 1013896 NP_688102.1 CDS SAG1093 NC_004116.1 1101899 1102783 R identified by match to PFAM protein family HMM PF00849; ribosomal large subunit pseudouridine synthase D complement(1101899..1102783) Streptococcus agalactiae 2603V/R 1013897 NP_688103.1 CDS ppnK NC_004116.1 1102780 1103616 R catalyzes the phosphorylation of NAD to NADP; inorganic polyphosphate/ATP-NAD kinase complement(1102780..1103616) Streptococcus agalactiae 2603V/R 1013898 NP_688104.1 CDS SAG1095 NC_004116.1 1103591 1104262 R similar to OMNI:NTL01SPL0878; identified by sequence similarity; GTP pyrophosphokinase complement(1103591..1104262) Streptococcus agalactiae 2603V/R 1013899 NP_688105.1 CDS SAG1096 NC_004116.1 1104372 1104944 D hypothetical protein 1104372..1104944 Streptococcus agalactiae 2603V/R 1013900 NP_688106.1 CDS prsA-2 NC_004116.1 1105121 1106095 D catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP; ribose-phosphate pyrophosphokinase 1105121..1106095 Streptococcus agalactiae 2603V/R 1013901 NP_688107.1 CDS iscS-1 NC_004116.1 1106099 1107214 D identified by match to PFAM protein family HMM PF00266; cysteine desulfurase 1106099..1107214 Streptococcus agalactiae 2603V/R 1013902 NP_688108.1 CDS SAG1099 NC_004116.1 1107216 1107563 D hypothetical protein 1107216..1107563 Streptococcus agalactiae 2603V/R 1013903 NP_688109.1 CDS SAG1100 NC_004116.1 1107724 1108356 D modulates transcription in response to the NADH/NAD(+) redox state; redox-sensing transcriptional repressor Rex 1107724..1108356 Streptococcus agalactiae 2603V/R 1013904 NP_688110.1 CDS radC NC_004116.1 1108369 1109049 R Involved in DNA double-strand break repair and recombination. Promotes the annealing of complementary single-stranded DNA and by simulation of RAD51 recombinase; DNA repair protein RadC complement(1108369..1109049) Streptococcus agalactiae 2603V/R 1013905 NP_688111.1 CDS SAG1102 NC_004116.1 1109145 1110278 R identified by match to PFAM protein family HMM PF01594; hypothetical protein complement(1109145..1110278) Streptococcus agalactiae 2603V/R 1013906 NP_688112.1 CDS arb NC_004116.1 1110369 1111805 R required for arbutin uptake and metabolism; 6-phospho-beta-glucosidase complement(1110369..1111805) Streptococcus agalactiae 2603V/R 1013907 NP_688113.1 CDS SAG1104 NC_004116.1 1111968 1112582 R platelet activating factor complement(1111968..1112582) Streptococcus agalactiae 2603V/R 1013908 NP_688114.1 CDS SAG1105 NC_004116.1 1112683 1113504 R identified by match to PFAM protein family HMM PF00702; HAD superfamily hydrolase complement(1112683..1113504) Streptococcus agalactiae 2603V/R 1013909 NP_688115.1 CDS SAG1106 NC_004116.1 1114129 1115058 D identified by match to PFAM protein family HMM PF00165; AraC family transcriptional regulator 1114129..1115058 Streptococcus agalactiae 2603V/R 1013910 NP_688116.1 CDS SAG1107 NC_004116.1 1115115 1116647 R identified by match to PFAM protein family HMM PF00654; voltage-gated chloride channel family protein complement(1115115..1116647) Streptococcus agalactiae 2603V/R 1013911 NP_688117.1 CDS potD NC_004116.1 1116756 1117829 R identified by match to PFAM protein family HMM PF01547; spermidine/putrescine ABC transporter spermidine/putrescine-binding protein complement(1116756..1117829) Streptococcus agalactiae 2603V/R 1013912 NP_688118.1 CDS potC NC_004116.1 1117822 1118598 R identified by match to PFAM protein family HMM PF00528; spermidine/putrescine ABC transporter permease complement(1117822..1118598) Streptococcus agalactiae 2603V/R 1013913 NP_688119.1 CDS potB NC_004116.1 1118595 1119389 R identified by match to PFAM protein family HMM PF00528; spermidine/putrescine ABC transporter permease complement(1118595..1119389) Streptococcus agalactiae 2603V/R 1013914 NP_688120.1 CDS potA NC_004116.1 1119373 1120527 R identified by match to PFAM protein family HMM PF00005; spermidine/putrescine ABC transporter ATP-binding protein complement(1119373..1120527) Streptococcus agalactiae 2603V/R 1013915 NP_688121.1 CDS murB NC_004116.1 1120576 1121478 R catalyzes the reduction of UDP-N-acetylglucosamine enolpyruvate to form UDP-N-acetylmuramate in peptidoglycan biosynthesis; UDP-N-acetylenolpyruvoylglucosamine reductase complement(1120576..1121478) Streptococcus agalactiae 2603V/R 1013916 NP_688122.1 CDS folK NC_004116.1 1121622 1122110 R identified by match to PFAM protein family HMM PF01288; 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase complement(1121622..1122110) Streptococcus agalactiae 2603V/R 1013917 NP_688123.1 CDS folB NC_004116.1 1122107 1122469 R identified by match to PFAM protein family HMM PF02152; dihydroneopterin aldolase complement(1122107..1122469) Streptococcus agalactiae 2603V/R 1013918 NP_688124.1 CDS folP NC_004116.1 1122471 1123274 R identified by match to PFAM protein family HMM PF00809; dihydropteroate synthase complement(1122471..1123274) Streptococcus agalactiae 2603V/R 1013919 NP_688125.1 CDS folE NC_004116.1 1123278 1123841 R involved in the first step of tetrahydrofolate biosynthesis; catalyzes the formation of formate and 2-amino-4-hydroxy-6-(erythro-1,2, 3-trihydroxypropyl)dihydropteridine triphosphate from GTP and water; forms a homopolymer; GTP cyclohydrolase I complement(1123278..1123841) Streptococcus agalactiae 2603V/R 1013920 NP_688126.1 CDS folC NC_004116.1 1123860 1125122 R identified by match to TIGR protein family HMM TIGR01499; folylpolyglutamate synthase complement(1123860..1125122) Streptococcus agalactiae 2603V/R 1013921 NP_688127.1 CDS rarD NC_004116.1 1125124 1126011 R identified by match to PFAM protein family HMM PF00892; rarD protein complement(1125124..1126011) Streptococcus agalactiae 2603V/R 1013922 NP_688128.1 CDS thrB NC_004116.1 1125998 1126864 R catalyzes the formation of O-phospho-L-homoserine from L-homoserine in threonine biosynthesis from asparate; homoserine kinase complement(1125998..1126864) Streptococcus agalactiae 2603V/R 1013923 NP_688129.1 CDS hom NC_004116.1 1126866 1128149 R catalyzes the formation of L-aspartate 4-semialdehyde from L-homoserine; homoserine dehydrogenase complement(1126866..1128149) Streptococcus agalactiae 2603V/R 1013924 NP_688130.1 CDS SAG1121 NC_004116.1 1128326 1129213 D identified by match to PFAM protein family HMM PF01522; polysaccharide deacetylase 1128326..1129213 Streptococcus agalactiae 2603V/R 1013925 NP_688131.1 CDS SAG1122 NC_004116.1 1129236 1130783 R identified by match to PFAM protein family HMM PF02028; transporter BCCT family protein complement(1129236..1130783) Streptococcus agalactiae 2603V/R 1013926 NP_688132.1 CDS SAG1123 NC_004116.1 1130793 1130897 R hypothetical protein complement(1130793..1130897) Streptococcus agalactiae 2603V/R 1013927 NP_688133.1 CDS SAG1124 NC_004116.1 1130926 1132302 R identified by match to PFAM protein family HMM PF00171; aldehyde dehydrogenase complement(1130926..1132302) Streptococcus agalactiae 2603V/R 1013928 NP_688134.1 CDS SAG1125 NC_004116.1 1132376 1133383 R hypothetical protein complement(1132376..1133383) Streptococcus agalactiae 2603V/R 1013929 NP_688135.1 CDS SAG1126 NC_004116.1 1133491 1134177 R similar to OMNI:NTL01SPL0680; identified by sequence similarity; The product of this gene was detected by Western blot analysis. For details on the method see Tettelin et al. 2002.; hypothetical protein complement(1133491..1134177) Streptococcus agalactiae 2603V/R 1013930 NP_688136.1 CDS SAG1127 NC_004116.1 1134596 1135936 D similar to OMNI:NTL01SA1825; identified by sequence similarity; hypothetical protein 1134596..1135936 Streptococcus agalactiae 2603V/R 1013931 NP_688137.1 CDS SAG1128 NC_004116.1 1136133 1136330 D identified by match to PFAM protein family HMM PF01381; Cro/CI family transcriptional regulator 1136133..1136330 Streptococcus agalactiae 2603V/R 1013932 NP_688138.1 CDS SAG1129 NC_004116.1 1136375 1136485 D hypothetical protein 1136375..1136485 Streptococcus agalactiae 2603V/R 1013933 NP_688139.1 CDS SAG1130 NC_004116.1 1136814 1136963 D hypothetical protein 1136814..1136963 Streptococcus agalactiae 2603V/R 1013934 NP_688140.1 CDS tpx NC_004116.1 1137039 1137533 R antioxidant activity; thioredoxin-dependent thiol peroxidase; forms homodimers in solution; shows substrate specificity to alkyl hydroperoxides; periplasmic protein; thiol peroxidase complement(1137039..1137533) Streptococcus agalactiae 2603V/R 1013935 NP_688141.1 CDS SAG1132 NC_004116.1 1137606 1138265 R hypothetical protein complement(1137606..1138265) Streptococcus agalactiae 2603V/R 1013936 NP_688142.1 CDS SAG1133 NC_004116.1 1138265 1139029 R hypothetical protein complement(1138265..1139029) Streptococcus agalactiae 2603V/R 1013937 NP_688143.1 CDS SAG1134 NC_004116.1 1139034 1139675 R identified by match to PFAM protein family HMM PF00392; GntR family transcriptional regulator complement(1139034..1139675) Streptococcus agalactiae 2603V/R 1013938 NP_688144.1 CDS SAG1135 NC_004116.1 1139839 1140390 R similar to OMNI:EF0080; identified by sequence similarity; gls24 protein complement(1139839..1140390) Streptococcus agalactiae 2603V/R 1013939 NP_688145.1 CDS SAG1136 NC_004116.1 1140412 1140609 R hypothetical protein complement(1140412..1140609) Streptococcus agalactiae 2603V/R 1013940 NP_688146.1 CDS SAG1137 NC_004116.1 1140656 1141198 R similar to OMNI:EF0604; identified by sequence similarity; gls24 protein complement(1140656..1141198) Streptococcus agalactiae 2603V/R 1013941 NP_688147.1 CDS SAG1138 NC_004116.1 1141254 1141448 R hypothetical protein complement(1141254..1141448) Streptococcus agalactiae 2603V/R 1013942 NP_688148.1 CDS SAG1139 NC_004116.1 1141458 1142039 R hypothetical protein complement(1141458..1142039) Streptococcus agalactiae 2603V/R 1013943 NP_688149.1 CDS SAG1140 NC_004116.1 1142054 1142302 R hypothetical protein complement(1142054..1142302) Streptococcus agalactiae 2603V/R 1013944 NP_688150.1 CDS SAG1141 NC_004116.1 1142350 1142688 R hypothetical protein complement(1142350..1142688) Streptococcus agalactiae 2603V/R 1013945 NP_688151.1 CDS pcrA NC_004116.1 1143007 1145286 R identified by match to PFAM protein family HMM PF00580; ATP-dependent DNA helicase PcrA complement(1143007..1145286) Streptococcus agalactiae 2603V/R 1013946 NP_688152.1 CDS SAG1143 NC_004116.1 1145392 1145778 R hypothetical protein complement(1145392..1145778) Streptococcus agalactiae 2603V/R 1013947 NP_688153.1 CDS uraA NC_004116.1 1145911 1147236 R identified by match to PFAM protein family HMM PF00860; uracil permease complement(1145911..1147236) Streptococcus agalactiae 2603V/R 1013948 NP_688154.1 CDS SAG1145 NC_004116.1 1147833 1149179 D identified by match to PFAM protein family HMM PF01235; sodium:alanine symporter family protein 1147833..1149179 Streptococcus agalactiae 2603V/R 1013949 NP_688155.1 CDS SAG1146 NC_004116.1 1149243 1150478 D identified by match to PFAM protein family HMM PF01545; cation efflux family protein 1149243..1150478 Streptococcus agalactiae 2603V/R 1013950 NP_688156.1 CDS SAG1147 NC_004116.1 1150637 1151029 D hypothetical protein 1150637..1151029 Streptococcus agalactiae 2603V/R 1013951 NP_688157.1 CDS SAG1148 NC_004116.1 1151010 1151705 D hypothetical protein 1151010..1151705 Streptococcus agalactiae 2603V/R 1013952 NP_688158.1 CDS SAG1149 NC_004116.1 1151774 1152397 D similar to OMNI:NTL01SPL1018; identified by sequence similarity; hypothetical protein 1151774..1152397 Streptococcus agalactiae 2603V/R 1013953 NP_688159.1 CDS rpsA NC_004116.1 1152810 1154012 R in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins; 30S ribosomal protein S1 complement(1152810..1154012) Streptococcus agalactiae 2603V/R 1013955 NP_688160.1 CDS SAG1151 NC_004116.1 1154356 1154586 R hypothetical protein complement(1154356..1154586) Streptococcus agalactiae 2603V/R 1013958 NP_688161.1 CDS ilvE NC_004116.1 1154670 1155692 R catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids; branched-chain amino acid aminotransferase complement(1154670..1155692) Streptococcus agalactiae 2603V/R 1013959 NP_688162.1 CDS parC NC_004116.1 1155806 1158265 R decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling; DNA topoisomerase IV subunit A complement(1155806..1158265) Streptococcus agalactiae 2603V/R 1013960 NP_688163.1 CDS parE NC_004116.1 1158399 1160360 R decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling; DNA topoisomerase IV subunit B complement(1158399..1160360) Streptococcus agalactiae 2603V/R 1013961 NP_688164.1 CDS SAG1155 NC_004116.1 1160462 1161100 D involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsX; glycerol-3-phosphate acyltransferase PlsY 1160462..1161100 Streptococcus agalactiae 2603V/R 1013962 NP_688165.1 CDS ung NC_004116.1 1161166 1161819 R Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine; uracil-DNA glycosylase complement(1161166..1161819) Streptococcus agalactiae 2603V/R 1013963 NP_688166.1 CDS SAG1157 NC_004116.1 1161918 1162403 R hypothetical protein complement(1161918..1162403) Streptococcus agalactiae 2603V/R 1013964 NP_688167.1 CDS neuA NC_004116.1 1162517 1163758 R identified by match to PFAM protein family HMM PF02348; CMP-N-acetylneuraminic acid synthetase NeuA complement(1162517..1163758) Streptococcus agalactiae 2603V/R 1013965 NP_688168.1 CDS neuD NC_004116.1 1163769 1164398 R neuD protein complement(1163769..1164398) Streptococcus agalactiae 2603V/R 1013966 NP_688169.1 CDS neuC NC_004116.1 1164395 1165549 R UDP-N-acetylglucosamine-2-epimerase NeuC complement(1164395..1165549) Streptococcus agalactiae 2603V/R 1013967 NP_688170.1 CDS neuB NC_004116.1 1165626 1166651 R identified by match to PFAM protein family HMM PF01354; N-acetyl neuramic acid synthetase NeuB complement(1165626..1166651) Streptococcus agalactiae 2603V/R 1013968 NP_688171.1 CDS cpsL NC_004116.1 1166651 1168051 R identified by match to PFAM protein family HMM PF01943; polysaccharide biosynthesis protein CpsL complement(1166651..1168051) Streptococcus agalactiae 2603V/R 1013969 NP_688172.1 CDS cpsK NC_004116.1 1168048 1169004 R similar to GP:13549137; identified by sequence similarity; polysaccharide biosynthesis protein CpsK(V) complement(1168048..1169004) Streptococcus agalactiae 2603V/R 1013970 NP_688173.1 CDS cpsJ NC_004116.1 1169001 1169966 R identified by match to PFAM protein family HMM PF00535; glycosyl transferase CpsJ(V) complement(1169001..1169966) Streptococcus agalactiae 2603V/R 1013971 NP_688174.1 CDS cpsO NC_004116.1 1169959 1170942 R identified by match to PFAM protein family HMM PF00535; glycosyl transferase CpsO(V) complement(1169959..1170942) Streptococcus agalactiae 2603V/R 1013972 NP_688175.1 CDS cpsN NC_004116.1 1170946 1171833 R identified by match to PFAM protein family HMM PF00535; glycosyl transferase CpsN(V) complement(1170946..1171833) Streptococcus agalactiae 2603V/R 1013973 NP_688176.1 CDS cpsM NC_004116.1 1171859 1172584 R similar to GP:13549133; identified by sequence similarity; polysaccharide biosynthesis protein CpsM(V) complement(1171859..1172584) Streptococcus agalactiae 2603V/R 1013974 NP_688177.1 CDS cpsH NC_004116.1 1172623 1173717 R similar to GP:13549132; identified by sequence similarity; polysaccharide biosynthesis protein cpsH(V) complement(1172623..1173717) Streptococcus agalactiae 2603V/R 1013975 NP_688178.1 CDS cpsG NC_004116.1 1173704 1174195 R similar to GP:5823214; identified by sequence similarity; glycosyl transferase CpsG(V) complement(1173704..1174195) Streptococcus agalactiae 2603V/R 1013976 NP_688179.1 CDS cpsF NC_004116.1 1174195 1174644 R similar to GP:13549130; identified by sequence similarity; polysaccharide biosynthesis protein CpsF complement(1174195..1174644) Streptococcus agalactiae 2603V/R 1013977 NP_688180.1 CDS cpsE NC_004116.1 1174668 1176056 R identified by match to PFAM protein family HMM PF02397; glycosyl transferase CpsE complement(1174668..1176056) Streptococcus agalactiae 2603V/R 1013978 NP_688181.1 CDS cpsD NC_004116.1 1176069 1176758 R identified by match to TIGR protein family HMM TIGR01007; cpsD protein complement(1176069..1176758) Streptococcus agalactiae 2603V/R 1013979 NP_688182.1 CDS cpsC NC_004116.1 1176769 1177461 R identified by match to PFAM protein family HMM PF02706; cpsC protein complement(1176769..1177461) Streptococcus agalactiae 2603V/R 1013980 NP_688183.1 CDS cpsB NC_004116.1 1177470 1178201 R identified by match to PFAM protein family HMM PF02811; capsular polysaccharide biosynthesis protein CpsB complement(1177470..1178201) Streptococcus agalactiae 2603V/R 1013981 NP_688184.1 CDS cpsA NC_004116.1 1178207 1179664 R identified by match to TIGR protein family HMM TIGR00350; capsular polysaccharide biosynthesis protein CpsA complement(1178207..1179664) Streptococcus agalactiae 2603V/R 1013982 NP_688185.1 CDS SAG1176 NC_004116.1 1179904 1180776 D identified by match to PFAM protein family HMM PF00126; LysR family transcriptional regulator 1179904..1180776 Streptococcus agalactiae 2603V/R 1013983 NP_688186.1 CDS SAG1177 NC_004116.1 1180801 1181568 R hypothetical protein complement(1180801..1181568) Streptococcus agalactiae 2603V/R 1013984 NP_688187.1 CDS deoD NC_004116.1 1181577 1182287 R catalyzes the reversible phosphorolysis of ribonucleosides and 2'- deoxyribonucleosides to the free base and (2'-deoxy)ribose-1- phosphate; purine nucleoside phosphorylase complement(1181577..1182287) Streptococcus agalactiae 2603V/R 1013985 NP_688188.1 CDS SAG1179 NC_004116.1 1182271 1183527 R identified by match to PFAM protein family HMM PF00654; voltage-gated chloride channel family protein complement(1182271..1183527) Streptococcus agalactiae 2603V/R 1013986 NP_688189.1 CDS deoD-2 NC_004116.1 1183529 1184338 R catalyzes the formation of a purine and ribose phosphate from a purine nucleoside; in E. coli this enzyme functions in xanthosine degradation; purine nucleoside phosphorylase complement(1183529..1184338) Streptococcus agalactiae 2603V/R 1013987 NP_688190.1 CDS arsC NC_004116.1 1184377 1184784 R arsenate reductase complement(1184377..1184784) Streptococcus agalactiae 2603V/R 1013988 NP_688191.1 CDS deoB-1 NC_004116.1 1184835 1186046 R catalyzes the transfer of phosphate between the C1 and C5 carbons of pentose; phosphopentomutase complement(1184835..1186046) Streptococcus agalactiae 2603V/R 1013989 NP_688192.1 CDS rpiA NC_004116.1 1186103 1186774 R Catalyzes D-ribose 5-phosphate --> D-ribulose 5-phosphate in the nonoxidative branch of the pentose phosphate pathway; ribose-5-phosphate isomerase A complement(1186103..1186774) Streptococcus agalactiae 2603V/R 1013990 NP_688193.1 CDS SAG1184 NC_004116.1 1187012 1187722 R hypothetical protein complement(1187012..1187722) Streptococcus agalactiae 2603V/R 1013991 NP_688194.1 CDS estA NC_004116.1 1187812 1188600 R similar to GP:7453518; identified by sequence similarity; tributyrin esterase complement(1187812..1188600) Streptococcus agalactiae 2603V/R 1013992 NP_688195.1 CDS SAG1186 NC_004116.1 1188657 1190318 R identified by match to PFAM protein family HMM PF00753; metallo-beta-lactamase superfamily protein complement(1188657..1190318) Streptococcus agalactiae 2603V/R 1013993 NP_688196.1 CDS SAG1187 NC_004116.1 1190614 1191375 R identified by match to PFAM protein family HMM PF00005; ABC transporter ATP-binding protein complement(1190614..1191375) Streptococcus agalactiae 2603V/R 1013994 NP_688197.1 CDS SAG1188 NC_004116.1 1191375 1192238 R ABC transporter permease complement(1191375..1192238) Streptococcus agalactiae 2603V/R 1013995 NP_688198.1 CDS SAG1189 NC_004116.1 1192251 1193255 R hypothetical protein complement(1192251..1193255) Streptococcus agalactiae 2603V/R 1013996 NP_688199.1 CDS pavA NC_004116.1 1193614 1195269 D similar to OMNI:SP0966; identified by sequence similarity; adherence and virulence protein A 1193614..1195269 Streptococcus agalactiae 2603V/R 1013997 NP_688200.1 CDS budA NC_004116.1 1195323 1196042 R identified by match to PFAM protein family HMM PF03306; alpha-acetolactate decarboxylase complement(1195323..1196042) Streptococcus agalactiae 2603V/R 1013998 NP_688201.1 CDS ilvK NC_004116.1 1196056 1197738 R catalyzes the formation of 2-acetolactate from pyruvate in stationary phase; acetolactate synthase complement(1196056..1197738) Streptococcus agalactiae 2603V/R 1013999 NP_688202.1 CDS SAG1193 NC_004116.1 1197848 1199074 R identified by match to PFAM protein family HMM PF00515; hypothetical protein complement(1197848..1199074) Streptococcus agalactiae 2603V/R 1014000 NP_688203.1 CDS SAG1194 NC_004116.1 1199064 1200254 R identified by match to PFAM protein family HMM PF01594; hypothetical protein complement(1199064..1200254) Streptococcus agalactiae 2603V/R 1014001 NP_688204.1 CDS SAG1195 NC_004116.1 1200346 1200807 R identified by match to PFAM protein family HMM PF00293; MutT/nudix family protein complement(1200346..1200807) Streptococcus agalactiae 2603V/R 1014002 NP_688205.1 CDS mutX NC_004116.1 1200797 1201279 R identified by match to PFAM protein family HMM PF00293; mutator MutT protein complement(1200797..1201279) Streptococcus agalactiae 2603V/R 1014003 NP_688206.1 CDS SAG1197 NC_004116.1 1201497 1204715 D identified by match to PFAM protein family HMM PF02278; hyaluronate lyase 1201497..1204715 Streptococcus agalactiae 2603V/R 1014004 NP_688207.1 CDS rfbB NC_004116.1 1204767 1205813 R identified by match to PFAM protein family HMM PF01370; dTDP-glucose 4,6-dehydratase complement(1204767..1205813) Streptococcus agalactiae 2603V/R 1014005 NP_688208.1 CDS SAG1199 NC_004116.1 1206020 1206613 R identified by match to PFAM protein family HMM PF00908; dTDP-4-keto-6-deoxyglucose-3,5-epimerase complement(1206020..1206613) Streptococcus agalactiae 2603V/R 1014006 NP_688209.1 CDS rfbA NC_004116.1 1206613 1207482 R identified by match to PFAM protein family HMM PF00483; glucose-1-phosphate thymidylyltransferase complement(1206613..1207482) Streptococcus agalactiae 2603V/R 1014007 NP_688210.1 CDS SAG1201 NC_004116.1 1207541 1208644 R identified by match to PFAM protein family HMM PF01266; iminodiacetate oxidase complement(1207541..1208644) Streptococcus agalactiae 2603V/R 1014008 NP_688211.1 CDS SAG1202 NC_004116.1 1208653 1209441 R hypothetical protein complement(1208653..1209441) Streptococcus agalactiae 2603V/R 1014009 NP_688212.1 CDS SAG1203 NC_004116.1 1209431 1210114 R hypothetical protein complement(1209431..1210114) Streptococcus agalactiae 2603V/R 1014010 NP_688213.1 CDS SAG1204 NC_004116.1 1210218 1210898 R identified by match to TIGR protein family HMM TIGR01446; DNA replication protein DnaD complement(1210218..1210898) Streptococcus agalactiae 2603V/R 1014011 NP_688214.1 CDS apt NC_004116.1 1211016 1211534 R catalyzes a salvage reaction resulting in the formation of AMP which is metabolically less costly than a de novo synthesis; adenine phosphoribosyltransferase complement(1211016..1211534) Streptococcus agalactiae 2603V/R 1014012 NP_688215.1 CDS SAG1206 NC_004116.1 1211657 1214221 R hypothetical protein complement(1211657..1214221) Streptococcus agalactiae 2603V/R 1014013 NP_688216.1 CDS SAG1207 NC_004116.1 1214205 1214303 R hypothetical protein complement(1214205..1214303) Streptococcus agalactiae 2603V/R 1014014 NP_688217.1 CDS recJ NC_004116.1 1214373 1216571 R identified by match to PFAM protein family HMM PF01368; single-stranded-DNA-specific exonuclease RecJ complement(1214373..1216571) Streptococcus agalactiae 2603V/R 1014015 NP_688218.1 CDS SAG1209 NC_004116.1 1216568 1217329 R identified by match to PFAM protein family HMM PF00106; short chain dehydrogenase/reductase family oxidoreductase complement(1216568..1217329) Streptococcus agalactiae 2603V/R 1014016 NP_688219.1 CDS SAG1210 NC_004116.1 1217331 1218260 R member of metallo-beta-lactamase family; the purified enzyme from Escherichia coli forms dimeric zinc phosphodiesterase; in Bacillus subtilis this protein is a 3'-tRNA processing endoribonuclease and is essential while in Escherichia coli it is not; associates with two zinc ions; ribonuclease Z complement(1217331..1218260) Streptococcus agalactiae 2603V/R 1014017 NP_688220.1 CDS SAG1211 NC_004116.1 1218302 1218949 R hypothetical protein complement(1218302..1218949) Streptococcus agalactiae 2603V/R 1014018 NP_688221.1 CDS hflX NC_004116.1 1218942 1220180 R identified by match to TIGR protein family HMM TIGR00231; GTP-binding protein HflX complement(1218942..1220180) Streptococcus agalactiae 2603V/R 1014019 NP_688222.1 CDS miaA NC_004116.1 1220271 1221161 R IPP transferase; isopentenyltransferase; involved in tRNA modification; in Escherichia coli this enzyme catalyzes the addition of a delta2-isopentenyl group from dimethylallyl diphosphate to the N6-nitrogen of adenosine adjacent to the anticodon of tRNA species that read codons starting with uracil; further tRNA modifications may occur; mutations in miaA result in defects in translation efficiency and fidelity; tRNA delta(2)-isopentenylpyrophosphate transferase complement(1220271..1221161) Streptococcus agalactiae 2603V/R 1014020 NP_688223.1 CDS SAG1214 NC_004116.1 1221272 1221448 D hypothetical protein 1221272..1221448 Streptococcus agalactiae 2603V/R 1014021 NP_688224.1 CDS SAG1215 NC_004116.1 1221490 1222407 R similar to OMNI:SA1184; identified by sequence similarity; hypothetical protein complement(1221490..1222407) Streptococcus agalactiae 2603V/R 1014022 NP_688225.1 CDS SAG1216 NC_004116.1 1222542 1226300 R identified by match to PFAM protein family HMM PF00128; pullulanase complement(1222542..1226300) Streptococcus agalactiae 2603V/R 1014023 NP_688226.1 CDS SAG1218 NC_004116.1 1227217 1227801 R hypothetical protein complement(1227217..1227801) Streptococcus agalactiae 2603V/R 1014025 NP_688227.1 CDS SAG1219 NC_004116.1 1227898 1229304 R divalent metal ion-dependent extracellular dipeptidase; able to hydrolyze a broad range of dipeptides but no tri-, tetra-, or larger oligopeptides; differences in the amino acid specificity of the cleavage site varies between species; similar to succinyl-diaminopimelate desuccinylases; dipeptidase PepV complement(1227898..1229304) Streptococcus agalactiae 2603V/R 1014026 NP_688228.1 CDS SAG1220 NC_004116.1 1229351 1229953 R identified by match to PFAM protein family HMM PF00881; nitroreductase family protein complement(1229351..1229953) Streptococcus agalactiae 2603V/R 1014027 NP_688229.1 CDS uvrC NC_004116.1 1231946 1233727 R The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision; excinuclease ABC subunit C complement(1231946..1233727) Streptococcus agalactiae 2603V/R 1014029 NP_688230.1 CDS SAG1223 NC_004116.1 1233886 1234653 D hypothetical protein 1233886..1234653 Streptococcus agalactiae 2603V/R 1014030 NP_688231.1 CDS SAG1224 NC_004116.1 1234712 1236052 R identified by match to PFAM protein family HMM PF01554; MATE efflux family protein complement(1234712..1236052) Streptococcus agalactiae 2603V/R 1014031 NP_688232.1 CDS SAG1225 NC_004116.1 1236152 1236562 R hypothetical protein complement(1236152..1236562) Streptococcus agalactiae 2603V/R 1014032 NP_688233.1 CDS SAG1226 NC_004116.1 1236572 1237069 R hypothetical protein complement(1236572..1237069) Streptococcus agalactiae 2603V/R 1014033 NP_688234.1 CDS SAG1227 NC_004116.1 1237291 1237887 D similar to GB:AL009126; identified by sequence similarity; The product of this gene was detected by Western blot analysis. For details on the method see Tettelin et al. 2002.; hypothetical protein 1237291..1237887 Streptococcus agalactiae 2603V/R 1014034 NP_688235.1 CDS SAG1228 NC_004116.1 1238076 1238366 D identified by match to PFAM protein family HMM PF01527; ISSdy1, transposase OrfA 1238076..1238366 Streptococcus agalactiae 2603V/R 1014035 NP_688236.1 CDS SAG1229 NC_004116.1 1238402 1239181 D identified by match to PFAM protein family HMM PF00665; ISSdy1, transposase OrfB 1238402..1239181 Streptococcus agalactiae 2603V/R 1014036 NP_688237.1 CDS SAG1230 NC_004116.1 1239405 1239695 D hypothetical protein 1239405..1239695 Streptococcus agalactiae 2603V/R 1014037 NP_688238.1 CDS SAG1233 NC_004116.1 1241015 1243483 R identified by match to TIGR protein family HMM TIGR01363; The product of this gene was detected by Western blot analysis. For details on the method see Tettelin et al. 2002.; streptococcal histidine triad family protein complement(1241015..1243483) Streptococcus agalactiae 2603V/R 1014040 NP_688239.1 CDS lmb NC_004116.1 1243496 1244416 R identified by match to PFAM protein family HMM PF01297; laminin-binding surface protein complement(1243496..1244416) Streptococcus agalactiae 2603V/R 1014041 NP_688240.1 CDS SAG1235 NC_004116.1 1244650 1245927 R identified by match to PFAM protein family HMM PF00078; GBSi1, group II intron, maturase complement(1244650..1245927) Streptococcus agalactiae 2603V/R 1014042 NP_688241.1 CDS SAG1237 NC_004116.1 1250615 1251949 R hypothetical protein complement(1250615..1251949) Streptococcus agalactiae 2603V/R 1014044 NP_688242.1 CDS SAG1238 NC_004116.1 1252057 1252665 R hypothetical protein complement(1252057..1252665) Streptococcus agalactiae 2603V/R 1014045 NP_688243.1 CDS SAG1239 NC_004116.1 1252715 1252945 R hypothetical protein complement(1252715..1252945) Streptococcus agalactiae 2603V/R 1014046 NP_688244.1 CDS SAG1241 NC_004116.1 1253409 1253684 D identified by match to PFAM protein family HMM PF01527; IS3 family transposase OrfA 1253409..1253684 Streptococcus agalactiae 2603V/R 1014048 NP_688245.1 CDS SAG1243 NC_004116.1 1254003 1254293 D identified by match to PFAM protein family HMM PF01527; ISSdy1, transposase OrfA 1254003..1254293 Streptococcus agalactiae 2603V/R 1014050 NP_688246.1 CDS SAG1244 NC_004116.1 1254329 1255108 D identified by match to PFAM protein family HMM PF00665; ISSdy1, transposase OrfB 1254329..1255108 Streptococcus agalactiae 2603V/R 1014051 NP_688247.1 CDS SAG1245 NC_004116.1 1255213 1255329 R hypothetical protein complement(1255213..1255329) Streptococcus agalactiae 2603V/R 1014052 NP_688248.1 CDS SAG1246 NC_004116.1 1255316 1256485 D hypothetical protein 1255316..1256485 Streptococcus agalactiae 2603V/R 1014053 NP_688249.1 CDS SAG1247 NC_004116.1 1256680 1257879 R identified by match to PFAM protein family HMM PF00589; phage integrase family site specific recombinase complement(1256680..1257879) Streptococcus agalactiae 2603V/R 1014054 NP_688250.1 CDS SAG1248 NC_004116.1 1257902 1258129 R hypothetical protein complement(1257902..1258129) Streptococcus agalactiae 2603V/R 1014055 NP_688251.1 CDS SAG1249 NC_004116.1 1258408 1258632 R identified by match to PFAM protein family HMM PF01381; Cro/CI family transcriptional regulator complement(1258408..1258632) Streptococcus agalactiae 2603V/R 1014056 NP_688252.1 CDS SAG1250 NC_004116.1 1258813 1260678 R identified by match to PFAM protein family HMM PF03432; Tn5252, relaxase complement(1258813..1260678) Streptococcus agalactiae 2603V/R 1014057 NP_688253.1 CDS SAG1251 NC_004116.1 1260665 1261030 R similar to OMNI:SP1055; identified by sequence similarity; Tn5252, ORF 9 protein complement(1260665..1261030) Streptococcus agalactiae 2603V/R 1014058 NP_688254.1 CDS SAG1252 NC_004116.1 1261037 1261399 R similar to OMNI:SP1054; identified by sequence similarity; Tn5252, ORF 10 protein complement(1261037..1261399) Streptococcus agalactiae 2603V/R 1014059 NP_688255.1 CDS SAG1253 NC_004116.1 1261820 1263127 R identified by match to PFAM protein family HMM PF01610; This gene is located in a transposable element that also encodes two genes for a mercuric resistance operon, and there are two copies of the transposable element in this strain.; ISL3 family transposase complement(1261820..1263127) Streptococcus agalactiae 2603V/R 1014060 NP_688256.1 CDS merA-1 NC_004116.1 1263287 1264927 R identified by match to PFAM protein family HMM PF00070; mercuric reductase complement(1263287..1264927) Streptococcus agalactiae 2603V/R 1014061 NP_688257.1 CDS merR-1 NC_004116.1 1264956 1265348 R identified by match to PFAM protein family HMM PF00376; mercuric resistance operon regulatory protein MerR complement(1264956..1265348) Streptococcus agalactiae 2603V/R 1014062 NP_688258.1 CDS SAG1257 NC_004116.1 1266612 1268741 R identified by match to PFAM protein family HMM PF00122; cation transporter E1-E2 family ATPase complement(1266612..1268741) Streptococcus agalactiae 2603V/R 1014064 NP_688259.1 CDS cadC NC_004116.1 1268734 1269102 R identified by match to PFAM protein family HMM PF01022; cadmium efflux system accessory protein complement(1268734..1269102) Streptococcus agalactiae 2603V/R 1014065 NP_688260.1 CDS SAG1259 NC_004116.1 1269305 1269604 D hypothetical protein 1269305..1269604 Streptococcus agalactiae 2603V/R 1014066 NP_688261.1 CDS SAG1260 NC_004116.1 1269658 1270446 R hypothetical protein complement(1269658..1270446) Streptococcus agalactiae 2603V/R 1014067 NP_688262.1 CDS SAG1261 NC_004116.1 1270455 1271051 D hypothetical protein 1270455..1271051 Streptococcus agalactiae 2603V/R 1014068 NP_688263.1 CDS SAG1262 NC_004116.1 1271225 1273312 R identified by match to PFAM protein family HMM PF00122; cation transporter E1-E2 family ATPase complement(1271225..1273312) Streptococcus agalactiae 2603V/R 1014069 YP_008592387.1 CDS SAG_RS02360 NC_004116.1 1273451 1273657 R hypothetical protein complement(1273451..1273657) Streptococcus agalactiae 2603V/R 17097510 NP_688264.1 CDS SAG1264 NC_004116.1 1274268 1274714 R similar to GP:9965434; identified by sequence similarity; transcriptional repressor CopY complement(1274268..1274714) Streptococcus agalactiae 2603V/R 1014071 NP_688265.1 CDS SAG1265 NC_004116.1 1275139 1275759 R cadmium resistance transporter complement(1275139..1275759) Streptococcus agalactiae 2603V/R 1014072 NP_688266.1 CDS SAG1266 NC_004116.1 1276299 1276757 D hypothetical protein 1276299..1276757 Streptococcus agalactiae 2603V/R 1014073 NP_688267.1 CDS SAG1267 NC_004116.1 1276791 1277117 D hypothetical protein 1276791..1277117 Streptococcus agalactiae 2603V/R 1014074 NP_688268.1 CDS SAG1268 NC_004116.1 1277301 1277993 D identified by match to PFAM protein family HMM PF01381; repressor protein 1277301..1277993 Streptococcus agalactiae 2603V/R 1014075 NP_688269.1 CDS SAG1269 NC_004116.1 1277996 1278130 D hypothetical protein 1277996..1278130 Streptococcus agalactiae 2603V/R 1014076 NP_688270.1 CDS SAG1270 NC_004116.1 1278136 1279551 D identified by match to PFAM protein family HMM PF00817; ImpB/MucB/SamB family protein 1278136..1279551 Streptococcus agalactiae 2603V/R 1014077 NP_688271.1 CDS SAG1271 NC_004116.1 1279548 1279898 D hypothetical protein 1279548..1279898 Streptococcus agalactiae 2603V/R 1014078 NP_688272.1 CDS SAG1272 NC_004116.1 1279885 1280193 D hypothetical protein 1279885..1280193 Streptococcus agalactiae 2603V/R 1014079 NP_688273.1 CDS SAG1273 NC_004116.1 1280202 1280558 R hypothetical protein complement(1280202..1280558) Streptococcus agalactiae 2603V/R 1014080 NP_688274.1 CDS SAG1274 NC_004116.1 1280548 1280937 R hypothetical protein complement(1280548..1280937) Streptococcus agalactiae 2603V/R 1014081 NP_688275.1 CDS SAG1275 NC_004116.1 1280934 1281161 R hypothetical protein complement(1280934..1281161) Streptococcus agalactiae 2603V/R 1014082 NP_688276.1 CDS SAG1276 NC_004116.1 1281215 1282291 R hypothetical protein complement(1281215..1282291) Streptococcus agalactiae 2603V/R 1014083 NP_688277.1 CDS SAG1277 NC_004116.1 1282330 1282821 R hypothetical protein complement(1282330..1282821) Streptococcus agalactiae 2603V/R 1014084 NP_688278.1 CDS SAG1278 NC_004116.1 1283064 1283354 R hypothetical protein complement(1283064..1283354) Streptococcus agalactiae 2603V/R 1014085 NP_688279.1 CDS SAG1279 NC_004116.1 1283368 1283667 R similar to GP:2735477; identified by sequence similarity; hypothetical protein complement(1283368..1283667) Streptococcus agalactiae 2603V/R 1014086 NP_688280.1 CDS SAG1280 NC_004116.1 1283738 1290562 R identified by match to PFAM protein family HMM PF00176; SNF2 family protein complement(1283738..1290562) Streptococcus agalactiae 2603V/R 1014087 NP_688281.1 CDS SAG1281 NC_004116.1 1290611 1291162 R hypothetical protein complement(1290611..1291162) Streptococcus agalactiae 2603V/R 1014088 NP_688282.1 CDS SAG1282 NC_004116.1 1291146 1291337 R similar to OMNI:EF0591; identified by sequence similarity; calcium-binding protein complement(1291146..1291337) Streptococcus agalactiae 2603V/R 1014089 NP_688283.1 CDS ssp-5 NC_004116.1 1291338 1296233 R identified by match to TIGR protein family HMM TIGR01167; The product of this gene was detected by Western blot analysis. For details on the method see Tettelin et al. 2002.; agglutinin receptor complement(1291338..1296233) Streptococcus agalactiae 2603V/R 1014090 NP_688284.1 CDS abiGI NC_004116.1 1296512 1297102 D similar to PID:1039476; identified by sequence similarity; abortive infection protein AbiGI 1296512..1297102 Streptococcus agalactiae 2603V/R 1014091 NP_688285.1 CDS abiGII NC_004116.1 1297099 1297944 D similar to GP:12620628; identified by sequence similarity; abortive infection protein AbiGII 1297099..1297944 Streptococcus agalactiae 2603V/R 1014092 NP_688286.1 CDS SAG1286 NC_004116.1 1298030 1300831 R Tn5252, Orf28 complement(1298030..1300831) Streptococcus agalactiae 2603V/R 1014093 NP_688287.1 CDS SAG1287 NC_004116.1 1300833 1303163 R The product of this gene was detected by Western blot analysis. For details on the method see Tettelin et al. 2002.; Tn5252, Orf26 complement(1300833..1303163) Streptococcus agalactiae 2603V/R 1014094 NP_688288.1 CDS SAG1289 NC_004116.1 1303556 1304410 R similar to GP:11559691; identified by sequence similarity; Tn5252, Orf23 complement(1303556..1304410) Streptococcus agalactiae 2603V/R 1014096 NP_688289.1 CDS SAG1290 NC_004116.1 1304429 1304671 R hypothetical protein complement(1304429..1304671) Streptococcus agalactiae 2603V/R 1014097 NP_688290.1 CDS SAG1292 NC_004116.1 1306506 1306994 R hypothetical protein complement(1306506..1306994) Streptococcus agalactiae 2603V/R 1014099 NP_688291.1 CDS SAG1293 NC_004116.1 1307071 1307655 R identified by match to PFAM protein family HMM PF02517; protease complement(1307071..1307655) Streptococcus agalactiae 2603V/R 1014100 NP_688292.1 CDS SAG1294 NC_004116.1 1307658 1307891 R hypothetical protein complement(1307658..1307891) Streptococcus agalactiae 2603V/R 1014101 NP_688293.1 CDS SAG1295 NC_004116.1 1307900 1308283 R hypothetical protein complement(1307900..1308283) Streptococcus agalactiae 2603V/R 1014102 NP_688294.1 CDS SAG1296 NC_004116.1 1308294 1308722 R hypothetical protein complement(1308294..1308722) Streptococcus agalactiae 2603V/R 1014103 NP_688295.1 CDS SAG1297 NC_004116.1 1308706 1310061 R identified by match to PFAM protein family HMM PF00145; C-5 cytosine-specific DNA methylase complement(1308706..1310061) Streptococcus agalactiae 2603V/R 1014104 NP_688296.1 CDS SAG1298 NC_004116.1 1310113 1310208 R hypothetical protein complement(1310113..1310208) Streptococcus agalactiae 2603V/R 1014105 NP_688297.1 CDS SAG1299 NC_004116.1 1310210 1311028 R hypothetical protein complement(1310210..1311028) Streptococcus agalactiae 2603V/R 1014106 NP_688298.1 CDS SAG1300 NC_004116.1 1311025 1311198 R hypothetical protein complement(1311025..1311198) Streptococcus agalactiae 2603V/R 1014107 NP_688299.1 CDS rplL NC_004116.1 1311397 1311762 R present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulates GTPase activity of translation factors; 50S ribosomal protein L7/L12 complement(1311397..1311762) Streptococcus agalactiae 2603V/R 1014108 NP_688300.1 CDS rplJ NC_004116.1 1311826 1312326 R binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit; 50S ribosomal protein L10 complement(1311826..1312326) Streptococcus agalactiae 2603V/R 1014109 NP_688301.1 CDS SAG1303 NC_004116.1 1312759 1314867 D identified by match to PFAM protein family HMM PF00004; ATP-dependent Clp protease, ATP-binding subunit 1312759..1314867 Streptococcus agalactiae 2603V/R 1014110 NP_688302.1 CDS SAG1304 NC_004116.1 1314851 1314949 R hypothetical protein complement(1314851..1314949) Streptococcus agalactiae 2603V/R 1014111 NP_688303.1 CDS mmuM NC_004116.1 1314960 1315904 R converts homocysteine and S-adenosyl-methionine to methionine and S-adenosyl-homocysteine or S-methyl-methionine and homocysteine to two methionines; homocysteine methyltransferase complement(1314960..1315904) Streptococcus agalactiae 2603V/R 1014112 NP_688304.1 CDS SAG1306 NC_004116.1 1315909 1317285 R identified by match to PFAM protein family HMM PF00324; amino acid permease complement(1315909..1317285) Streptococcus agalactiae 2603V/R 1014113 NP_688305.1 CDS SAG1307 NC_004116.1 1317415 1318065 R hypothetical protein complement(1317415..1318065) Streptococcus agalactiae 2603V/R 1014114 NP_688306.1 CDS SAG1308 NC_004116.1 1318223 1318726 R hypothetical protein complement(1318223..1318726) Streptococcus agalactiae 2603V/R 1014115 NP_688307.1 CDS SAG1309 NC_004116.1 1318723 1318815 R hypothetical protein complement(1318723..1318815) Streptococcus agalactiae 2603V/R 1014116 NP_688308.1 CDS SAG1310 NC_004116.1 1318818 1319366 D identified by match to PFAM protein family HMM PF00440; TetR family transcriptional regulator 1318818..1319366 Streptococcus agalactiae 2603V/R 1014117 NP_688309.1 CDS engB NC_004116.1 1319428 1320024 R binds guanine nucleotides; in Escherichia coli depletion results in defective cell division and filamentation; in Bacillus subtilis this gene is essential; ribosome biogenesis GTP-binding protein YsxC complement(1319428..1320024) Streptococcus agalactiae 2603V/R 1014118 NP_688310.1 CDS clpX NC_004116.1 1320035 1321261 R binds and unfolds substrates as part of the ClpXP protease; ATP-dependent protease ATP-binding subunit ClpX complement(1320035..1321261) Streptococcus agalactiae 2603V/R 1014119 NP_688311.1 CDS SAG1313 NC_004116.1 1321291 1321461 R hypothetical protein complement(1321291..1321461) Streptococcus agalactiae 2603V/R 1014120 NP_688312.1 CDS folA NC_004116.1 1321479 1321973 R identified by match to PFAM protein family HMM PF00186; dihydrofolate reductase complement(1321479..1321973) Streptococcus agalactiae 2603V/R 1014121 NP_688313.1 CDS thyA NC_004116.1 1322053 1322892 R ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived; thymidylate synthase complement(1322053..1322892) Streptococcus agalactiae 2603V/R 1014122 NP_688314.1 CDS SAG1316 NC_004116.1 1323046 1324218 D identified by match to PFAM protein family HMM PF01154; HMG-CoA synthase 1323046..1324218 Streptococcus agalactiae 2603V/R 1014123 NP_688315.1 CDS SAG1317 NC_004116.1 1324220 1325503 D identified by match to PFAM protein family HMM PF00368; 3-hydroxy-3-methylglutaryl-CoA reductase 1324220..1325503 Streptococcus agalactiae 2603V/R 1014124 NP_688316.1 CDS SAG1318 NC_004116.1 1325595 1326044 D hypothetical protein 1325595..1326044 Streptococcus agalactiae 2603V/R 1014125 NP_688317.1 CDS SAG1319 NC_004116.1 1326049 1326693 D identified by match to PFAM protein family HMM PF03006; hemolysin III 1326049..1326693 Streptococcus agalactiae 2603V/R 1014126 NP_688318.1 CDS SAG1320 NC_004116.1 1326780 1327694 D hypothetical protein 1326780..1327694 Streptococcus agalactiae 2603V/R 1014127 NP_688319.1 CDS SAG1321 NC_004116.1 1327795 1328649 D hypothetical protein 1327795..1328649 Streptococcus agalactiae 2603V/R 1014128 NP_688320.1 CDS SAG1322 NC_004116.1 1328695 1328913 R similar to OMNI:SP1775; identified by sequence similarity; hypothetical protein complement(1328695..1328913) Streptococcus agalactiae 2603V/R 1014129 NP_688321.1 CDS SAG1323 NC_004116.1 1328981 1329976 R catalyzes the isomerization of isopentenyl pyrophosphate to dimethylallyl diphosphate; isopentenyl pyrophosphate isomerase complement(1328981..1329976) Streptococcus agalactiae 2603V/R 1014130 NP_688322.1 CDS SAG1324 NC_004116.1 1329973 1330965 R identified by match to TIGR protein family HMM TIGR01220; phosphomevalonate kinase complement(1329973..1330965) Streptococcus agalactiae 2603V/R 1014131 NP_688323.1 CDS mvaD NC_004116.1 1330958 1331902 R identified by match to PFAM protein family HMM PF00288; diphosphomevalonate decarboxylase complement(1330958..1331902) Streptococcus agalactiae 2603V/R 1014132 NP_688324.1 CDS SAG1326 NC_004116.1 1331884 1332762 R identified by match to PFAM protein family HMM PF00288; mevalonate kinase complement(1331884..1332762) Streptococcus agalactiae 2603V/R 1014133 NP_688325.1 CDS SAG1327 NC_004116.1 1332878 1334107 R identified by match to PFAM protein family HMM PF00512; sensor histidine kinase complement(1332878..1334107) Streptococcus agalactiae 2603V/R 1014134 NP_688326.1 CDS SAG1328 NC_004116.1 1334107 1334793 R identified by match to PFAM protein family HMM PF00072; DNA-binding response regulator complement(1334107..1334793) Streptococcus agalactiae 2603V/R 1014135 NP_688327.1 CDS SAG1329 NC_004116.1 1334795 1335421 R similar to OMNI:NTL01SPL0666; identified by sequence similarity; GTP pyrophosphokinase complement(1334795..1335421) Streptococcus agalactiae 2603V/R 1014136 NP_688328.1 CDS SAG1330 NC_004116.1 1335570 1335776 R hypothetical protein complement(1335570..1335776) Streptococcus agalactiae 2603V/R 1014137 NP_688329.1 CDS SAG1331 NC_004116.1 1336428 1339367 R identified by match to PFAM protein family HMM PF00746; hypothetical protein complement(1336428..1339367) Streptococcus agalactiae 2603V/R 1014138 NP_688330.1 CDS SAG1332 NC_004116.1 1340126 1340566 R identified by match to PFAM protein family HMM PF01047; MarR family transcriptional regulator complement(1340126..1340566) Streptococcus agalactiae 2603V/R 1014139 NP_688331.1 CDS SAG1333 NC_004116.1 1340840 1342912 D identified by match to PFAM protein family HMM PF00149; 5'-nucleotidase 1340840..1342912 Streptococcus agalactiae 2603V/R 1014140 NP_688332.1 CDS SAG1334 NC_004116.1 1342949 1343359 R cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+); peptide deformylase complement(1342949..1343359) Streptococcus agalactiae 2603V/R 1014141 NP_688333.1 CDS gdhA NC_004116.1 1343429 1344778 R converts 2-oxoglutarate to glutamate; in Escherichia coli this enzyme plays a role in glutamate synthesis when the cell is under energy restriction; uses NADPH; forms a homohexamer; glutamate dehydrogenase complement(1343429..1344778) Streptococcus agalactiae 2603V/R 1014142 NP_688334.1 CDS SAG1336 NC_004116.1 1344946 1345455 D identified by sequence similarity; hypothetical protein 1344946..1345455 Streptococcus agalactiae 2603V/R 1014143 NP_688335.1 CDS SAG1337 NC_004116.1 1345496 1347265 R identified by match to PFAM protein family HMM PF00005; ABC transporter ATP-binding protein/permease complement(1345496..1347265) Streptococcus agalactiae 2603V/R 1014144 NP_688336.1 CDS SAG1338 NC_004116.1 1347270 1349009 R identified by match to PFAM protein family HMM PF00005; ABC transporter ATP-binding protein/permease complement(1347270..1349009) Streptococcus agalactiae 2603V/R 1014145 NP_688337.1 CDS SAG1339 NC_004116.1 1349076 1349549 R identified by match to PFAM protein family HMM PF00583; acetyltransferase complement(1349076..1349549) Streptococcus agalactiae 2603V/R 1014146 NP_688338.1 CDS SAG1340 NC_004116.1 1349546 1351414 R identified by match to PFAM protein family HMM PF00005; ABC transporter ATP-binding protein complement(1349546..1351414) Streptococcus agalactiae 2603V/R 1014147 NP_688339.1 CDS SAG1341 NC_004116.1 1351425 1352633 R catalyzes the addition and repair of the 3'-terminal CCA sequence in tRNA; these proteins belong to the CCA-adding enzyme subfamily 2 which does not have phosphohydrolase activity; tRNA CCA-pyrophosphorylase complement(1351425..1352633) Streptococcus agalactiae 2603V/R 1014148 NP_688340.1 CDS SAG1342 NC_004116.1 1352818 1353666 R identified by match to PFAM protein family HMM PF02645; DegV family protein complement(1352818..1353666) Streptococcus agalactiae 2603V/R 1014149 NP_688341.1 CDS SAG1343 NC_004116.1 1353666 1354046 R similar to OMNI:NTL01SPL0660; identified by sequence similarity; The product of this gene was detected by Western blot analysis. For details on the method see Tettelin et al. 2002.; hypothetical protein complement(1353666..1354046) Streptococcus agalactiae 2603V/R 1014150 NP_688342.1 CDS SAG1344 NC_004116.1 1354118 1354651 R hypothetical protein complement(1354118..1354651) Streptococcus agalactiae 2603V/R 1014151 NP_688343.1 CDS SAG1345 NC_004116.1 1354702 1355196 R hypothetical protein complement(1354702..1355196) Streptococcus agalactiae 2603V/R 1014152 NP_688344.1 CDS SAG1346 NC_004116.1 1355385 1357349 R identified by match to PFAM protein family HMM PF00359; PTS system fructose specific transporter subunit IIABC complement(1355385..1357349) Streptococcus agalactiae 2603V/R 1014153 NP_688345.1 CDS fruK NC_004116.1 1357346 1358257 R identified by match to PFAM protein family HMM PF00294; 1-phosphofructokinase complement(1357346..1358257) Streptococcus agalactiae 2603V/R 1014154 NP_688346.1 CDS lacR-1 NC_004116.1 1358254 1358997 R identified by match to PFAM protein family HMM PF00455; lactose phosphotransferase system repressor complement(1358254..1358997) Streptococcus agalactiae 2603V/R 1014155 NP_688347.1 CDS SAG1349 NC_004116.1 1359128 1360363 R identified by match to PFAM protein family HMM PF02388; beta-lactam resistance factor complement(1359128..1360363) Streptococcus agalactiae 2603V/R 1014156 NP_688348.1 CDS SAG1350 NC_004116.1 1360507 1362141 R identified by match to TIGR protein family HMM TIGR01168; surface antigen-like protein complement(1360507..1362141) Streptococcus agalactiae 2603V/R 1014157 NP_688349.1 CDS SAG1351 NC_004116.1 1362353 1363276 R ketopantoate reductase; catalyzes the NADPH reduction of ketopantoate to pantoate; functions in pantothenate (vitamin B5) biosynthesis; 2-dehydropantoate 2-reductase complement(1362353..1363276) Streptococcus agalactiae 2603V/R 1014158 NP_688350.1 CDS SAG1352 NC_004116.1 1363289 1364359 R similar to OMNI:NTL01SPL0650; identified by sequence similarity; hypothetical protein complement(1363289..1364359) Streptococcus agalactiae 2603V/R 1014159 NP_688351.1 CDS SAG1353 NC_004116.1 1364496 1365488 R identified by match to PFAM protein family HMM PF00070; pyridine nucleotide-disulfide oxidoreductase family protein complement(1364496..1365488) Streptococcus agalactiae 2603V/R 1014160 NP_688352.1 CDS trmD NC_004116.1 1365469 1366224 R methylates guanosine-37 in various tRNAs; uses S-adenosyl-L-methionine to transfer methyl group to tRNA; tRNA (guanine-N(1)-)-methyltransferase complement(1365469..1366224) Streptococcus agalactiae 2603V/R 1014161 NP_688353.1 CDS rimM NC_004116.1 1366211 1366729 R Essential for efficient processing of 16S rRNA; 16S rRNA-processing protein RimM complement(1366211..1366729) Streptococcus agalactiae 2603V/R 1014162 NP_688354.1 CDS SAG1356 NC_004116.1 1367051 1368562 R similar to GB:U01312 PID:460083; identified by sequence similarity; RofA family transcriptional regulator complement(1367051..1368562) Streptococcus agalactiae 2603V/R 1014165 NP_688355.1 CDS SAG1357 NC_004116.1 1368694 1368936 R identified by match to PFAM protein family HMM PF00013; KH domain-containing protein complement(1368694..1368936) Streptococcus agalactiae 2603V/R 1014166 NP_688356.1 CDS rpsP NC_004116.1 1368946 1369218 R binds to lower part of 30S body where it stabilizes two domains; required for efficient assembly of 30S; in Escherichia coli this protein has nuclease activity; 30S ribosomal protein S16 complement(1368946..1369218) Streptococcus agalactiae 2603V/R 1014167 NP_688357.1 CDS SAG1359 NC_004116.1 1369347 1370594 R identified by match to PFAM protein family HMM PF02687; permease complement(1369347..1370594) Streptococcus agalactiae 2603V/R 1014168 NP_688358.1 CDS SAG1360 NC_004116.1 1370609 1371319 R identified by match to PFAM protein family HMM PF00005; ABC transporter ATP-binding protein complement(1370609..1371319) Streptococcus agalactiae 2603V/R 1014169 NP_688359.1 CDS SAG1361 NC_004116.1 1371322 1372566 R hypothetical protein complement(1371322..1372566) Streptococcus agalactiae 2603V/R 1014170 NP_688360.1 CDS SAG1362 NC_004116.1 1372768 1374366 R identified by match to PFAM protein family HMM PF02787; carbamoyl-phosphate synthase large subunit complement(1372768..1374366) Streptococcus agalactiae 2603V/R 1014171 NP_688361.1 CDS carA-2 NC_004116.1 1374422 1375492 R catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers; carbamoyl phosphate synthase small subunit complement(1374422..1375492) Streptococcus agalactiae 2603V/R 1014172 NP_688362.1 CDS pyrR NC_004116.1 1375541 1376062 R regulates pyrimidine biosynthesis by binding to the mRNA of the pyr genes, also has been shown to have uracil phosphoribosyltransferase activity; bifunctional pyrimidine regulatory protein PyrR/uracil phosphoribosyltransferase complement(1375541..1376062) Streptococcus agalactiae 2603V/R 1014173 NP_688363.1 CDS SAG1365 NC_004116.1 1376238 1377128 R identified by match to PFAM protein family HMM PF00849; ribosomal large subunit pseudouridine synthase D complement(1376238..1377128) Streptococcus agalactiae 2603V/R 1014174 NP_688364.1 CDS lspA NC_004116.1 1377112 1377576 R lipoprotein signal peptidase; integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis; lipoprotein signal peptidase complement(1377112..1377576) Streptococcus agalactiae 2603V/R 1014175 NP_688365.1 CDS SAG1367 NC_004116.1 1377585 1378490 R identified by match to PFAM protein family HMM PF00126; LysR family transcriptional regulator complement(1377585..1378490) Streptococcus agalactiae 2603V/R 1014176 NP_688366.1 CDS rpmA NC_004116.1 1378706 1378990 R involved in the peptidyltransferase reaction during translation; 50S ribosomal protein L27 complement(1378706..1378990) Streptococcus agalactiae 2603V/R 1014177 NP_688367.1 CDS SAG1369 NC_004116.1 1379021 1379359 R hypothetical protein complement(1379021..1379359) Streptococcus agalactiae 2603V/R 1014178 NP_688368.1 CDS rplU NC_004116.1 1379366 1379680 R identified by match to PFAM protein family HMM PF00829; 50S ribosomal protein L21 complement(1379366..1379680) Streptococcus agalactiae 2603V/R 1014179 NP_688369.1 CDS SAG1371 NC_004116.1 1379870 1381048 R hypothetical protein complement(1379870..1381048) Streptococcus agalactiae 2603V/R 1014180 NP_688370.1 CDS thiI NC_004116.1 1381150 1382364 R Required for the synthesis of the thiazole moiety; thiamine biosynthesis protein ThiI complement(1381150..1382364) Streptococcus agalactiae 2603V/R 1014181 NP_688371.1 CDS iscS-2 NC_004116.1 1382366 1383511 R identified by match to PFAM protein family HMM PF00266; cysteine desulfurase complement(1382366..1383511) Streptococcus agalactiae 2603V/R 1014182 NP_688372.1 CDS SAG1374 NC_004116.1 1383758 1384210 D hypothetical protein 1383758..1384210 Streptococcus agalactiae 2603V/R 1014183 NP_688373.1 CDS gor NC_004116.1 1384253 1385602 R catalyzes the reduction of 2 glutathione to glutathione disulfide; maintains high levels of reduced glutathione in the cytosol; involved in redox regulation and oxidative defense; glutathione reductase complement(1384253..1385602) Streptococcus agalactiae 2603V/R 1014184 NP_688374.1 CDS SAG1376 NC_004116.1 1385777 1386112 R hypothetical protein complement(1385777..1386112) Streptococcus agalactiae 2603V/R 1014185 NP_688375.1 CDS aroC NC_004116.1 1386196 1387362 R catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis; chorismate synthase complement(1386196..1387362) Streptococcus agalactiae 2603V/R 1014186 NP_688376.1 CDS aroB NC_004116.1 1387363 1388430 R catalyzes the formation of 3-dehydroquinate from 3-deoxy-arabino-heptulonate 7-phosphate; functions in aromatic amino acid biosynthesis; 3-dehydroquinate synthase complement(1387363..1388430) Streptococcus agalactiae 2603V/R 1014187 NP_688377.1 CDS aroD NC_004116.1 1388524 1389201 R catalyzes the dehydration of 3-dehydroquinate to form 3-dehydroshikimate in aromatic amino acid biosynthesis; 3-dehydroquinate dehydratase complement(1388524..1389201) Streptococcus agalactiae 2603V/R 1014188 NP_688378.1 CDS SAG1380 NC_004116.1 1389201 1390358 R hypothetical protein complement(1389201..1390358) Streptococcus agalactiae 2603V/R 1014189 NP_688379.1 CDS SAG1381 NC_004116.1 1390493 1392637 D identified by match to PFAM protein family HMM PF00884; sulfatase 1390493..1392637 Streptococcus agalactiae 2603V/R 1014190 NP_688380.1 CDS rplT NC_004116.1 1392879 1393238 R binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit; 50S ribosomal protein L20 complement(1392879..1393238) Streptococcus agalactiae 2603V/R 1014191 NP_688381.1 CDS rpmI NC_004116.1 1393296 1393496 R identified by match to PFAM protein family HMM PF01632; 50S ribosomal protein L35 complement(1393296..1393496) Streptococcus agalactiae 2603V/R 1014192 NP_688382.1 CDS infC NC_004116.1 1393536 1394066 R IF-3 has several functions that are required and promote translation initiation including; preventing association of 70S by binding to 30S; monitoring codon-anticodon interactions by promoting disassociation of fMet-tRNA(fMet) from initiation complexes formed on leaderless mRNAs or incorrectly bound noninitiatior tRNAs and complexes with noncanonical start sites; stimulates codon-anticodon interactions at P-site; involved in moving mRNA to the P-site; and in recycling subunits; translation initiation factor IF-3 complement(1393536..1394066) Streptococcus agalactiae 2603V/R 1014193 NP_688383.1 CDS cmk NC_004116.1 1394227 1394910 R Catalyzes the formation of (d)CDP from ATP and (d)CMP; cytidylate kinase complement(1394227..1394910) Streptococcus agalactiae 2603V/R 1014194 NP_688384.1 CDS SAG1386 NC_004116.1 1394921 1395445 R hypothetical protein complement(1394921..1395445) Streptococcus agalactiae 2603V/R 1014195 NP_688385.1 CDS SAG1387 NC_004116.1 1395491 1395688 D ferredoxin, 4Fe-4S 1395491..1395688 Streptococcus agalactiae 2603V/R 1014196 NP_688386.1 CDS SAG1388 NC_004116.1 1395675 1396166 R hypothetical protein complement(1395675..1396166) Streptococcus agalactiae 2603V/R 1014197 NP_688387.1 CDS pepT NC_004116.1 1396195 1397415 R catalyzes the release of the N-terminal amino acid from a tripeptide; peptidase T complement(1396195..1397415) Streptococcus agalactiae 2603V/R 1014198 NP_688388.1 CDS SAG1390 NC_004116.1 1397550 1399184 R identified by match to PFAM protein family HMM PF01943; polysaccharide biosynthesis protein complement(1397550..1399184) Streptococcus agalactiae 2603V/R 1014199 NP_688389.1 CDS murE NC_004116.1 1399308 1400762 D involved in cell wall formation; peptidoglycan synthesis; cytoplasmic enzyme; catalyzes the addition of lysine to UDP-N-acetylmuramoyl-L-alanyl-D-glutamate forming UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysine; UDP-N-acetylmuramoylalanyl-D-glutamate--L-lysine ligase 1399308..1400762 Streptococcus agalactiae 2603V/R 1014200 NP_688390.1 CDS SAG1392 NC_004116.1 1400918 1401712 D identified by match to PFAM protein family HMM PF00005; iron ABC transporter ATP-binding protein 1400918..1401712 Streptococcus agalactiae 2603V/R 1014201 NP_688391.1 CDS SAG1393 NC_004116.1 1401736 1402668 D identified by match to PFAM protein family HMM PF01497; iron ABC transporter substrate-binding protein 1401736..1402668 Streptococcus agalactiae 2603V/R 1014202 NP_688392.1 CDS SAG1394 NC_004116.1 1402684 1403709 D identified by match to PFAM protein family HMM PF01032; iron ABC transporter permease 1402684..1403709 Streptococcus agalactiae 2603V/R 1014203 NP_688393.1 CDS SAG1395 NC_004116.1 1403706 1404707 D identified by match to PFAM protein family HMM PF01032; iron ABC transporter permease 1403706..1404707 Streptococcus agalactiae 2603V/R 1014204 NP_688394.1 CDS SAG1396 NC_004116.1 1404736 1405389 R hypothetical protein complement(1404736..1405389) Streptococcus agalactiae 2603V/R 1014205 NP_688395.1 CDS ppa NC_004116.1 1405449 1406384 R catalyzes the hydrolysis of pyrophosphate to phosphate; manganese-dependent inorganic pyrophosphatase complement(1405449..1406384) Streptococcus agalactiae 2603V/R 1014206 NP_688396.1 CDS pflA-2 NC_004116.1 1406501 1407289 R identified by match to PFAM protein family HMM PF02143; pyruvate formate-lyase-activating enzyme complement(1406501..1407289) Streptococcus agalactiae 2603V/R 1014207 NP_688397.1 CDS SAG1399 NC_004116.1 1407357 1408691 R identified by match to PFAM protein family HMM PF00571; hypothetical protein complement(1407357..1408691) Streptococcus agalactiae 2603V/R 1014208 NP_688398.1 CDS SAG1400 NC_004116.1 1408871 1409437 R hypothetical protein complement(1408871..1409437) Streptococcus agalactiae 2603V/R 1014209 NP_688399.1 CDS SAG1401 NC_004116.1 1409430 1410365 R hypothetical protein complement(1409430..1410365) Streptococcus agalactiae 2603V/R 1014210 NP_688400.1 CDS SAG1402 NC_004116.1 1410458 1411099 R identified by match to PFAM protein family HMM PF01569; PAP2 family protein complement(1410458..1411099) Streptococcus agalactiae 2603V/R 1014211 NP_688401.1 CDS SAG1403 NC_004116.1 1411080 1411664 R similar to OMNI:NTL01SPL0281; identified by sequence similarity; hypothetical protein complement(1411080..1411664) Streptococcus agalactiae 2603V/R 1014212 NP_688402.1 CDS SAG1404 NC_004116.1 1411965 1412891 R identified by match to TIGR protein family HMM TIGR01167; The product of this gene was detected by Western blot analysis. For details on the method see Tettelin et al. 2002.; cell wall surface anchor family protein complement(1411965..1412891) Streptococcus agalactiae 2603V/R 1014213 NP_688403.1 CDS SAG1405 NC_004116.1 1412888 1413772 R identified by match to TIGR protein family HMM TIGR01076; The product of this gene was detected by Western blot analysis. For details on the method see Tettelin et al. 2002.; sortase family protein complement(1412888..1413772) Streptococcus agalactiae 2603V/R 1014214 NP_688404.1 CDS SAG1406 NC_004116.1 1413772 1414653 R identified by match to TIGR protein family HMM TIGR01076; sortase family protein complement(1413772..1414653) Streptococcus agalactiae 2603V/R 1014215 NP_688405.1 CDS SAG1407 NC_004116.1 1414765 1416882 R identified by match to TIGR protein family HMM TIGR01167; The product of this gene was detected by Western blot analysis. For details on the method see Tettelin et al. 2002.; cell wall surface anchor family protein complement(1414765..1416882) Streptococcus agalactiae 2603V/R 1014216 NP_688406.1 CDS SAG1408 NC_004116.1 1417012 1419717 R cell wall surface anchor family protein complement(1417012..1419717) Streptococcus agalactiae 2603V/R 1014217 NP_688407.1 CDS SAG1410 NC_004116.1 1421579 1422718 R identified by match to PFAM protein family HMM PF00534; glycoside hydrolase family protein complement(1421579..1422718) Streptococcus agalactiae 2603V/R 1014219 NP_688408.1 CDS SAG1411 NC_004116.1 1422708 1423556 R identified by match to PFAM protein family HMM PF00535; glycosyl transferase family protein complement(1422708..1423556) Streptococcus agalactiae 2603V/R 1014220 NP_688409.1 CDS SAG1412 NC_004116.1 1423553 1424977 R identified by match to PFAM protein family HMM PF01943; polysaccharide biosynthesis protein complement(1423553..1424977) Streptococcus agalactiae 2603V/R 1014221 NP_688410.1 CDS SAG1413 NC_004116.1 1424977 1426341 R hypothetical protein complement(1424977..1426341) Streptococcus agalactiae 2603V/R 1014222 NP_688411.1 CDS SAG1414 NC_004116.1 1426343 1427269 R identified by match to PFAM protein family HMM PF00535; glycosyl transferase family protein complement(1426343..1427269) Streptococcus agalactiae 2603V/R 1014223 NP_688412.1 CDS SAG1415 NC_004116.1 1427299 1428234 R identified by match to PFAM protein family HMM PF00535; glycosyl transferase family protein complement(1427299..1428234) Streptococcus agalactiae 2603V/R 1014224 NP_688413.1 CDS SAG1416 NC_004116.1 1428236 1429294 R nucleotide sugar dehydratase complement(1428236..1429294) Streptococcus agalactiae 2603V/R 1014225 NP_688414.1 CDS SAG1417 NC_004116.1 1429294 1430016 R identified by match to PFAM protein family HMM PF01128; nucleotidyl transferase complement(1429294..1430016) Streptococcus agalactiae 2603V/R 1014226 NP_688415.1 CDS SAG1418 NC_004116.1 1430016 1430840 R similar to OMNI:EF2168; identified by sequence similarity; polysaccharide biosynthesis protein complement(1430016..1430840) Streptococcus agalactiae 2603V/R 1014227 NP_688416.1 CDS SAG1419 NC_004116.1 1430865 1432598 R hypothetical protein complement(1430865..1432598) Streptococcus agalactiae 2603V/R 1014228 NP_688417.1 CDS SAG1420 NC_004116.1 1432591 1432944 R hypothetical protein complement(1432591..1432944) Streptococcus agalactiae 2603V/R 1014229 NP_688418.1 CDS SAG1421 NC_004116.1 1432941 1433672 R identified by match to PFAM protein family HMM PF00535; glycosyl transferase family protein complement(1432941..1433672) Streptococcus agalactiae 2603V/R 1014230 NP_688419.1 CDS SAG1422 NC_004116.1 1433674 1434615 R identified by match to PFAM protein family HMM PF00535; glycosyl transferase family protein complement(1433674..1434615) Streptococcus agalactiae 2603V/R 1014231 NP_688420.1 CDS SAG1423 NC_004116.1 1434605 1435759 R glycosyl transferase family protein complement(1434605..1435759) Streptococcus agalactiae 2603V/R 1014232 NP_688421.1 CDS rfbD NC_004116.1 1435876 1436730 R identified by match to TIGR protein family HMM TIGR01214; dTDP-4-dehydrorhamnose reductase complement(1435876..1436730) Streptococcus agalactiae 2603V/R 1014233 NP_688422.1 CDS SAG1425 NC_004116.1 1436820 1437161 R hypothetical protein complement(1436820..1437161) Streptococcus agalactiae 2603V/R 1014234 NP_688423.1 CDS rpoD NC_004116.1 1437270 1438379 R sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; primary sigma factor of bacterium; RNA polymerase sigma factor RpoD complement(1437270..1438379) Streptococcus agalactiae 2603V/R 1014235 NP_688424.1 CDS dnaG NC_004116.1 1438387 1440195 R synthesizes RNA primers at the replication forks; DNA primase complement(1438387..1440195) Streptococcus agalactiae 2603V/R 1014236 NP_688425.1 CDS mscL NC_004116.1 1440385 1440762 D identified by match to PFAM protein family HMM PF01741; large conductance mechanosensitive channel protein 1440385..1440762 Streptococcus agalactiae 2603V/R 1014237 NP_688426.1 CDS rpsU NC_004116.1 1440859 1441035 R a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA; 30S ribosomal protein S21 complement(1440859..1441035) Streptococcus agalactiae 2603V/R 1014238 NP_688427.1 CDS SAG1430 NC_004116.1 1441139 1441642 R hypothetical protein complement(1441139..1441642) Streptococcus agalactiae 2603V/R 1014239 NP_688428.1 CDS SAG1431 NC_004116.1 1441725 1442531 R identified by match to PFAM protein family HMM PF00497; amino acid ABC transporter amino acid-binding protein complement(1441725..1442531) Streptococcus agalactiae 2603V/R 1014240 NP_688429.1 CDS SAG1432 NC_004116.1 1442856 1443899 R identified by match to PFAM protein family HMM PF00909; ammonium transporter complement(1442856..1443899) Streptococcus agalactiae 2603V/R 1014241 NP_688430.1 CDS SAG1433 NC_004116.1 1443979 1445106 D hypothetical protein 1443979..1445106 Streptococcus agalactiae 2603V/R 1014242 NP_688431.1 CDS SAG1434 NC_004116.1 1445143 1446129 R identified by match to PFAM protein family HMM PF00581; hypothetical protein complement(1445143..1446129) Streptococcus agalactiae 2603V/R 1014243 NP_688432.1 CDS SAG1435 NC_004116.1 1446292 1446597 D hypothetical protein 1446292..1446597 Streptococcus agalactiae 2603V/R 1014244 NP_688433.1 CDS SAG1436 NC_004116.1 1446755 1448128 R glycerol-3-phosphate transporter complement(1446755..1448128) Streptococcus agalactiae 2603V/R 1014245 NP_688434.1 CDS SAG1437 NC_004116.1 1448236 1448403 D hypothetical protein 1448236..1448403 Streptococcus agalactiae 2603V/R 1014246 NP_688435.1 CDS glgP NC_004116.1 1448544 1450808 R identified by match to PFAM protein family HMM PF00343; glycogen phosphorylase complement(1448544..1450808) Streptococcus agalactiae 2603V/R 1014247 NP_688436.1 CDS malQ NC_004116.1 1450820 1452316 R amylomaltase; acts to release glucose from maltodextrins; 4-alpha-glucanotransferase complement(1450820..1452316) Streptococcus agalactiae 2603V/R 1014248 NP_688437.1 CDS SAG1440 NC_004116.1 1452437 1453465 R identified by match to PFAM protein family HMM PF00356; maltose operon repressor MalR complement(1452437..1453465) Streptococcus agalactiae 2603V/R 1014249 NP_688438.1 CDS SAG1441 NC_004116.1 1453721 1454968 D identified by match to PFAM protein family HMM PF01547; maltose/maltodextrin ABC transporter maltose/maltodextrin-binding protein 1453721..1454968 Streptococcus agalactiae 2603V/R 1014250 NP_688439.1 CDS SAG1442 NC_004116.1 1455066 1456436 D identified by match to PFAM protein family HMM PF00528; maltose ABC transporter permease 1455066..1456436 Streptococcus agalactiae 2603V/R 1014251 NP_688440.1 CDS SAG1443 NC_004116.1 1456436 1457272 D identified by match to PFAM protein family HMM PF00528; maltose ABC transporter permease 1456436..1457272 Streptococcus agalactiae 2603V/R 1014252 NP_688441.1 CDS SAG1444 NC_004116.1 1457503 1458975 D identified by match to PFAM protein family HMM PF00854; proton/peptide symporter family protein 1457503..1458975 Streptococcus agalactiae 2603V/R 1014253 NP_688442.1 CDS SAG1446 NC_004116.1 1459557 1459745 R hypothetical protein complement(1459557..1459745) Streptococcus agalactiae 2603V/R 1014255 NP_688443.1 CDS SAG1447 NC_004116.1 1459756 1461081 R hypothetical protein complement(1459756..1461081) Streptococcus agalactiae 2603V/R 1014256 NP_688444.1 CDS SAG1448 NC_004116.1 1461074 1462582 R identified by match to PFAM protein family HMM PF00534; glycoside hydrolase family protein complement(1461074..1462582) Streptococcus agalactiae 2603V/R 1014257 NP_688445.1 CDS SAG1449 NC_004116.1 1462596 1464983 R functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; in some organisms, especially gram positive pathogens, have paralogs that have been found to be nonessential but do function in secretion of a subset of exported proteins; preprotein translocase subunit SecA complement(1462596..1464983) Streptococcus agalactiae 2603V/R 1014258 NP_688446.1 CDS SAG1450 NC_004116.1 1464970 1465962 R similar to OMNI:SP1760; identified by sequence similarity; hypothetical protein complement(1464970..1465962) Streptococcus agalactiae 2603V/R 1014259 NP_688447.1 CDS SAG1451 NC_004116.1 1465959 1467443 R hypothetical protein complement(1465959..1467443) Streptococcus agalactiae 2603V/R 1014260 NP_688448.1 CDS SAG1452 NC_004116.1 1467525 1469069 R hypothetical protein complement(1467525..1469069) Streptococcus agalactiae 2603V/R 1014261 NP_688449.1 CDS secY NC_004116.1 1469069 1470298 R forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase; preprotein translocase subunit SecY complement(1469069..1470298) Streptococcus agalactiae 2603V/R 1014262 NP_688450.1 CDS SAG1454 NC_004116.1 1470422 1471618 R similar to GP:13346801; identified by sequence similarity; hypothetical protein complement(1470422..1471618) Streptococcus agalactiae 2603V/R 1014263 NP_688451.1 CDS SAG1455 NC_004116.1 1471679 1472566 R identified by match to PFAM protein family HMM PF00535; glycosyl transferase family protein complement(1471679..1472566) Streptococcus agalactiae 2603V/R 1014264 NP_688452.1 CDS SAG1457 NC_004116.1 1473647 1474036 R identified by match to PFAM protein family HMM PF01609; IS1381 transposase protein B complement(1473647..1474036) Streptococcus agalactiae 2603V/R 1014266 NP_688453.1 CDS SAG1458 NC_004116.1 1474069 1474452 R similar to OMNI:SP0537; identified by sequence similarity; IS1381 transposase protein A complement(1474069..1474452) Streptococcus agalactiae 2603V/R 1014267 NP_688454.1 CDS SAG1459 NC_004116.1 1474581 1475822 R identified by match to PFAM protein family HMM PF01501; glycosyl transferase family protein complement(1474581..1475822) Streptococcus agalactiae 2603V/R 1014268 NP_688455.1 CDS SAG1460 NC_004116.1 1475819 1477024 R identified by match to PFAM protein family HMM PF01501; glycosyl transferase family protein complement(1475819..1477024) Streptococcus agalactiae 2603V/R 1014269 NP_688456.1 CDS SAG1461 NC_004116.1 1477033 1478040 R hypothetical protein complement(1477033..1478040) Streptococcus agalactiae 2603V/R 1014270 NP_688457.1 CDS SAG1462 NC_004116.1 1478371 1481283 R identified by match to PFAM protein family HMM PF00746; cell wall surface anchor family protein complement(1478371..1481283) Streptococcus agalactiae 2603V/R 1014271 NP_688458.1 CDS uvrB NC_004116.1 1483259 1485250 R The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion; excinuclease ABC subunit B complement(1483259..1485250) Streptococcus agalactiae 2603V/R 1014273 NP_688459.1 CDS SAG1465 NC_004116.1 1485311 1486231 R identified by match to PFAM protein family HMM PF02517; protease complement(1485311..1486231) Streptococcus agalactiae 2603V/R 1014274 NP_688460.1 CDS glnP NC_004116.1 1486414 1488597 D identified by match to PFAM protein family HMM PF00497; glutamine ABC transporter glutamine-binding protein/permease 1486414..1488597 Streptococcus agalactiae 2603V/R 1014275 NP_688461.1 CDS SAG1467 NC_004116.1 1488597 1489337 D identified by match to PFAM protein family HMM PF00005; glutamine ABC transporter ATP-binding protein, GlnQ 1488597..1489337 Streptococcus agalactiae 2603V/R 1014276 NP_688462.1 CDS SAG1468 NC_004116.1 1489486 1489836 D hypothetical protein 1489486..1489836 Streptococcus agalactiae 2603V/R 1014277 NP_688463.1 CDS SAG1469 NC_004116.1 1489928 1490086 R hypothetical protein complement(1489928..1490086) Streptococcus agalactiae 2603V/R 1014278 NP_688464.2 CDS obgE NC_004116.1 1490112 1491419 R essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication; GTPase ObgE complement(1490112..1491419) Streptococcus agalactiae 2603V/R 1014279 NP_688465.1 CDS SAG1471 NC_004116.1 1491486 1491614 R hypothetical protein complement(1491486..1491614) Streptococcus agalactiae 2603V/R 1014280 NP_688466.1 CDS pepS NC_004116.1 1491811 1493052 D identified by match to PFAM protein family HMM PF02073; aminopeptidase 1491811..1493052 Streptococcus agalactiae 2603V/R 1014281 NP_688467.1 CDS SAG1473 NC_004116.1 1493086 1493664 R identified by match to TIGR protein family HMM TIGR01167; cell wall surface anchor family protein complement(1493086..1493664) Streptococcus agalactiae 2603V/R 1014282 NP_688468.1 CDS SAG1474 NC_004116.1 1493774 1495816 R identified by match to PFAM protein family HMM PF01425; amidase complement(1493774..1495816) Streptococcus agalactiae 2603V/R 1014283 NP_688469.1 CDS rsuA NC_004116.1 1495901 1496623 R identified by match to PFAM protein family HMM PF00849; ribosomal small subunit pseudouridine synthase A complement(1495901..1496623) Streptococcus agalactiae 2603V/R 1014284 NP_688470.1 CDS SAG1476 NC_004116.1 1496814 1497656 R identified by match to PFAM protein family HMM PF00248; aldo/keto reductase complement(1496814..1497656) Streptococcus agalactiae 2603V/R 1014285 NP_688471.1 CDS SAG1477 NC_004116.1 1497923 1498597 D identified by match to PFAM protein family HMM PF00881; nitroreductase family protein 1497923..1498597 Streptococcus agalactiae 2603V/R 1014286 NP_688472.1 CDS gloA NC_004116.1 1498685 1499077 D identified by match to PFAM protein family HMM PF00903; lactoylglutathione lyase 1498685..1499077 Streptococcus agalactiae 2603V/R 1014287 NP_688473.1 CDS SAG1479 NC_004116.1 1499206 1500132 D identified by match to PFAM protein family HMM PF00535; glycosyl transferase family protein 1499206..1500132 Streptococcus agalactiae 2603V/R 1014288 NP_688474.1 CDS SAG1480 NC_004116.1 1500261 1501649 D identified by match to PFAM protein family HMM PF00324; amino acid permease 1500261..1501649 Streptococcus agalactiae 2603V/R 1014289 NP_688475.1 CDS smpB NC_004116.1 1501733 1502200 R binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation; SsrA-binding protein complement(1501733..1502200) Streptococcus agalactiae 2603V/R 1014290 NP_688476.1 CDS vacB NC_004116.1 1502203 1504608 R identified by match to PFAM protein family HMM PF00575; VacB/Rnb family exoribonuclease complement(1502203..1504608) Streptococcus agalactiae 2603V/R 1014291 NP_688477.1 CDS secG NC_004116.1 1504721 1504957 R preprotein translocase subunit SecG complement(1504721..1504957) Streptococcus agalactiae 2603V/R 1014292 NP_688478.1 CDS rpmG NC_004116.1 1505004 1505150 R in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif; 50S ribosomal protein L33 complement(1505004..1505150) Streptococcus agalactiae 2603V/R 1014293 NP_688479.1 CDS SAG1485 NC_004116.1 1505147 1506316 R identified by match to PFAM protein family HMM PF00083; multi-drug resistance protein complement(1505147..1506316) Streptococcus agalactiae 2603V/R 1014294 NP_688480.1 CDS SAG1486 NC_004116.1 1506512 1508158 R hypothetical protein complement(1506512..1508158) Streptococcus agalactiae 2603V/R 1014295 NP_688481.1 CDS SAG1487 NC_004116.1 1508148 1508849 R identified by match to PFAM protein family HMM PF00005; ABC transporter ATP-binding protein complement(1508148..1508849) Streptococcus agalactiae 2603V/R 1014296 NP_688482.1 CDS coaE NC_004116.1 1508973 1509560 R catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; involved in coenzyme A biosynthesis; dephospho-CoA kinase complement(1508973..1509560) Streptococcus agalactiae 2603V/R 1014297 NP_688483.1 CDS mutM NC_004116.1 1509557 1510378 R Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases; formamidopyrimidine-DNA glycosylase complement(1509557..1510378) Streptococcus agalactiae 2603V/R 1014298 NP_688484.1 CDS SAG1490 NC_004116.1 1510527 1511375 R identified by match to PFAM protein family HMM PF01381; MutR family transcriptional regulator complement(1510527..1511375) Streptococcus agalactiae 2603V/R 1014299 NP_688485.1 CDS SAG1491 NC_004116.1 1511592 1513184 D hypothetical protein 1511592..1513184 Streptococcus agalactiae 2603V/R 1014300 NP_688486.1 CDS SAG1492 NC_004116.1 1513220 1513396 D hypothetical protein 1513220..1513396 Streptococcus agalactiae 2603V/R 1014301 NP_688487.1 CDS SAG1493 NC_004116.1 1513447 1513647 R hypothetical protein complement(1513447..1513647) Streptococcus agalactiae 2603V/R 1014302 NP_688488.1 CDS SAG1494 NC_004116.1 1513840 1513938 R hypothetical protein complement(1513840..1513938) Streptococcus agalactiae 2603V/R 1014303 NP_688489.1 CDS SAG1495 NC_004116.1 1514173 1514418 R identified by match to PFAM protein family HMM PF02517; CAAX amino terminal protease family protein complement(1514173..1514418) Streptococcus agalactiae 2603V/R 1014304 NP_688490.1 CDS SAG1496 NC_004116.1 1514446 1514778 R hypothetical protein complement(1514446..1514778) Streptococcus agalactiae 2603V/R 1014305 NP_688491.1 CDS SAG1497 NC_004116.1 1514880 1514993 R hypothetical protein complement(1514880..1514993) Streptococcus agalactiae 2603V/R 1014306 NP_688492.1 CDS SAG1498 NC_004116.1 1515157 1515558 R hypothetical protein complement(1515157..1515558) Streptococcus agalactiae 2603V/R 1014307 NP_688493.1 CDS era NC_004116.1 1515795 1516694 R Era; Escherichia coli Ras-like protein; Bex; Bacillus Era-complementing segment; essential protein in Escherichia coli that is involved in many cellular processes; GTPase; binds the cell membrane through apparent C-terminal domain; mutants are arrested during the cell cycle; Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome; GTP-binding protein Era complement(1515795..1516694) Streptococcus agalactiae 2603V/R 1014308 NP_688494.1 CDS dgkA NC_004116.1 1516736 1517134 R identified by match to PFAM protein family HMM PF01219; diacylglycerol kinase complement(1516736..1517134) Streptococcus agalactiae 2603V/R 1014309 NP_688495.1 CDS SAG1501 NC_004116.1 1517115 1517600 R metalloprotease complement(1517115..1517600) Streptococcus agalactiae 2603V/R 1014310 NP_688496.1 CDS SAG1502 NC_004116.1 1518007 1518813 R similar to SP:P39887; identified by sequence similarity; tetracenomycin polyketide synthesis O-methyltransferase TcmP complement(1518007..1518813) Streptococcus agalactiae 2603V/R 1014311 NP_688497.1 CDS SAG1503 NC_004116.1 1518858 1518977 R hypothetical protein complement(1518858..1518977) Streptococcus agalactiae 2603V/R 1014312 NP_688498.1 CDS SAG1504 NC_004116.1 1519014 1519130 R hypothetical protein complement(1519014..1519130) Streptococcus agalactiae 2603V/R 1014313 NP_688499.1 CDS SAG1505 NC_004116.1 1519135 1519611 R identified by match to PFAM protein family HMM PF00293; MutT/nudix family protein complement(1519135..1519611) Streptococcus agalactiae 2603V/R 1014314 NP_688500.1 CDS SAG1506 NC_004116.1 1519803 1520606 D hypothetical protein 1519803..1520606 Streptococcus agalactiae 2603V/R 1014315 NP_688501.1 CDS SAG1507 NC_004116.1 1520697 1521734 R identified by match to PFAM protein family HMM PF02562; PhoH family protein complement(1520697..1521734) Streptococcus agalactiae 2603V/R 1014316 NP_688502.1 CDS SAG1508 NC_004116.1 1521807 1523579 R in group A Streptococci this protein was found to cross react with anti myosin antibodies and may play a role in rheumatic fever; hypothetical protein complement(1521807..1523579) Streptococcus agalactiae 2603V/R 1014317 NP_688503.1 CDS SAG1509 NC_004116.1 1523736 1523951 R hypothetical protein complement(1523736..1523951) Streptococcus agalactiae 2603V/R 1014318 NP_688504.1 CDS msrA NC_004116.1 1523948 1524457 R this stereospecific enzymes reduces the S isomer of methionine sulfoxide while MsrB reduces the R form; provides protection against oxidative stress; methionine sulfoxide reductase A complement(1523948..1524457) Streptococcus agalactiae 2603V/R 1014319 NP_688505.1 CDS SAG1511 NC_004116.1 1524595 1525449 R hypothetical protein complement(1524595..1525449) Streptococcus agalactiae 2603V/R 1014320 NP_688506.1 CDS frr NC_004116.1 1525567 1526124 R Rrf; Frr; ribosome-recycling factor; release factor 4; RF4; recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G; A GTPase-dependent process results in release of 50S from 70S; inhibited by release factor RF-1; essential for viability; structurally similar to tRNAs; ribosome recycling factor complement(1525567..1526124) Streptococcus agalactiae 2603V/R 1014321 NP_688507.1 CDS pyrH NC_004116.1 1526140 1526868 R Catalyzes the phosphorylation of UMP to UDP; uridylate kinase complement(1526140..1526868) Streptococcus agalactiae 2603V/R 1014322 NP_688508.1 CDS SAG1514 NC_004116.1 1526989 1527669 R identified by match to PFAM protein family HMM PF00005; peptide ABC transporter ATP-binding protein complement(1526989..1527669) Streptococcus agalactiae 2603V/R 1014323 NP_688509.1 CDS SAG1515 NC_004116.1 1527656 1528444 R identified by match to PFAM protein family HMM PF00005; peptide ABC transporter ATP-binding protein complement(1527656..1528444) Streptococcus agalactiae 2603V/R 1014324 NP_688510.1 CDS SAG1516 NC_004116.1 1528432 1529199 R identified by match to PFAM protein family HMM PF00528; peptide ABC transporter permease complement(1528432..1529199) Streptococcus agalactiae 2603V/R 1014325 NP_688511.1 CDS SAG1517 NC_004116.1 1529238 1530182 R identified by match to PFAM protein family HMM PF00528; peptide ABC transporter permease complement(1529238..1530182) Streptococcus agalactiae 2603V/R 1014326 NP_688512.1 CDS SAG1518 NC_004116.1 1530169 1531785 R identified by match to PFAM protein family HMM PF00496; peptide ABC transporter substrate-binding protein complement(1530169..1531785) Streptococcus agalactiae 2603V/R 1014327 NP_688513.1 CDS rplA NC_004116.1 1532174 1532863 R in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA; 50S ribosomal protein L1 complement(1532174..1532863) Streptococcus agalactiae 2603V/R 1014328 NP_688514.1 CDS rplK NC_004116.1 1532967 1533392 R binds directly to 23S ribosomal RNA; 50S ribosomal protein L11 complement(1532967..1533392) Streptococcus agalactiae 2603V/R 1014329 NP_688515.1 CDS SAG1521 NC_004116.1 1533654 1534820 D identified by match to PFAM protein family HMM PF00665; IS30 family transposase 1533654..1534820 Streptococcus agalactiae 2603V/R 1014330 NP_688516.1 CDS SAG1522 NC_004116.1 1535154 1536536 R major facilitator transporter complement(1535154..1536536) Streptococcus agalactiae 2603V/R 1014331 NP_688517.1 CDS SAG1523 NC_004116.1 1536544 1537758 R identified by match to PFAM protein family HMM PF01546; M20/M25/M40 family peptidase complement(1536544..1537758) Streptococcus agalactiae 2603V/R 1014332 NP_688518.1 CDS SAG1524 NC_004116.1 1538037 1538921 D identified by match to PFAM protein family HMM PF00126; LysR family transcriptional regulator 1538037..1538921 Streptococcus agalactiae 2603V/R 1014333 NP_688519.1 CDS SAG1525 NC_004116.1 1538982 1539335 D hypothetical protein 1538982..1539335 Streptococcus agalactiae 2603V/R 1014334 NP_688520.1 CDS SAG1526 NC_004116.1 1539406 1539942 D IS861, transposase OrfA 1539406..1539942 Streptococcus agalactiae 2603V/R 1014335 NP_688521.1 CDS SAG1527 NC_004116.1 1539918 1540751 D identified by match to PFAM protein family HMM PF00665; IS861, transposase OrfB 1539918..1540751 Streptococcus agalactiae 2603V/R 1014336 NP_688522.1 CDS SAG1528 NC_004116.1 1540800 1542515 R identified by match to PFAM protein family HMM PF00425; chorismate binding protein complement(1540800..1542515) Streptococcus agalactiae 2603V/R 1014337 NP_688523.1 CDS SAG1529 NC_004116.1 1542597 1545047 R identified by match to PFAM protein family HMM PF01580; DNA translocase FtsK complement(1542597..1545047) Streptococcus agalactiae 2603V/R 1014338 NP_688524.1 CDS SAG1530 NC_004116.1 1545213 1546016 D identified by match to PFAM protein family HMM PF00160; cyclophilin type peptidyl-prolyl cis-trans isomerase 1545213..1546016 Streptococcus agalactiae 2603V/R 1014339 NP_688525.1 CDS SAG1531 NC_004116.1 1546068 1546901 R identified by match to PFAM protein family HMM PF00950; manganese ABC transporter permease complement(1546068..1546901) Streptococcus agalactiae 2603V/R 1014340 NP_688526.1 CDS SAG1532 NC_004116.1 1546903 1547619 R identified by match to PFAM protein family HMM PF00005; manganese ABC transporter ATP-binding protein complement(1546903..1547619) Streptococcus agalactiae 2603V/R 1014341 NP_688527.1 CDS SAG1533 NC_004116.1 1547790 1548716 R identified by match to PFAM protein family HMM PF01297; manganese ABC transporter manganese-binding adhesion liprotein complement(1547790..1548716) Streptococcus agalactiae 2603V/R 1014342 NP_688528.1 CDS SAG1534 NC_004116.1 1548883 1549530 D identified by match to PFAM protein family HMM PF01325; iron-dependent transcriptional regulator 1548883..1549530 Streptococcus agalactiae 2603V/R 1014343 NP_688529.1 CDS pfs NC_004116.1 1549570 1550259 R enables the cleavage of the glycosidic bond in both 5'-methylthioadenosine and S-adenosylhomocysteine; 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase complement(1549570..1550259) Streptococcus agalactiae 2603V/R 1014344 NP_688530.1 CDS SAG1536 NC_004116.1 1550269 1550538 R hypothetical protein complement(1550269..1550538) Streptococcus agalactiae 2603V/R 1014345 NP_688531.1 CDS SAG1537 NC_004116.1 1550538 1551092 R identified by match to PFAM protein family HMM PF00293; MutT/nudix family protein complement(1550538..1551092) Streptococcus agalactiae 2603V/R 1014346 NP_688532.1 CDS glmU NC_004116.1 1551113 1552492 R forms a homotrimer; catalyzes the acetylation of glucosamine-1-phosphate and uridylation of N-acetylglucosamine-1-phosphate to produce UDP-GlcNAc; function in cell wall synthesis; bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase complement(1551113..1552492) Streptococcus agalactiae 2603V/R 1014347 NP_688533.1 CDS SAG1539 NC_004116.1 1552634 1552729 D hypothetical protein 1552634..1552729 Streptococcus agalactiae 2603V/R 1014348 NP_688534.1 CDS SAG1540 NC_004116.1 1552736 1553149 R hypothetical protein complement(1552736..1553149) Streptococcus agalactiae 2603V/R 1014349 NP_688535.1 CDS SAG1541 NC_004116.1 1553162 1553539 R glyoxylase complement(1553162..1553539) Streptococcus agalactiae 2603V/R 1014350 NP_688536.1 CDS SAG1542 NC_004116.1 1553628 1554584 R identified by match to PFAM protein family HMM PF01408; Gfo/Idh/MocA family oxidoreductase complement(1553628..1554584) Streptococcus agalactiae 2603V/R 1014351 NP_688537.1 CDS fabG NC_004116.1 1555271 1555969 R Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis; 3-ketoacyl-ACP reductase complement(1555271..1555969) Streptococcus agalactiae 2603V/R 1014353 NP_688538.1 CDS SAG1545 NC_004116.1 1555962 1556198 R hypothetical protein complement(1555962..1556198) Streptococcus agalactiae 2603V/R 1014354 NP_688539.1 CDS SAG1546 NC_004116.1 1556288 1556536 R hypothetical protein complement(1556288..1556536) Streptococcus agalactiae 2603V/R 1014355 NP_688540.1 CDS SAG1547 NC_004116.1 1556734 1557234 R identified by match to PFAM protein family HMM PF00583; acetyltransferase complement(1556734..1557234) Streptococcus agalactiae 2603V/R 1014356 NP_688541.1 CDS SAG1548 NC_004116.1 1557474 1558742 R identified by match to PFAM protein family HMM PF00535; glycosyl transferase family protein complement(1557474..1558742) Streptococcus agalactiae 2603V/R 1014357 NP_688542.1 CDS SAG1549 NC_004116.1 1558750 1559133 D similar to OMNI:SP0537; identified by sequence similarity; IS1381 transposase protein A 1558750..1559133 Streptococcus agalactiae 2603V/R 1014358 NP_688543.1 CDS SAG1550 NC_004116.1 1559166 1559555 D identified by match to PFAM protein family HMM PF01609; IS1381 transposase protein B 1559166..1559555 Streptococcus agalactiae 2603V/R 1014359 NP_688544.1 CDS SAG1551 NC_004116.1 1559544 1559747 R hypothetical protein complement(1559544..1559747) Streptococcus agalactiae 2603V/R 1014360 NP_688545.1 CDS SAG1552 NC_004116.1 1559887 1562046 R hypothetical protein complement(1559887..1562046) Streptococcus agalactiae 2603V/R 1014361 NP_688546.1 CDS SAG1553 NC_004116.1 1562053 1563486 R hypothetical protein complement(1562053..1563486) Streptococcus agalactiae 2603V/R 1014362 NP_688547.1 CDS SAG1554 NC_004116.1 1563491 1564168 R hypothetical protein complement(1563491..1564168) Streptococcus agalactiae 2603V/R 1014363 NP_688548.1 CDS SAG1555 NC_004116.1 1564220 1564915 R hypothetical protein complement(1564220..1564915) Streptococcus agalactiae 2603V/R 1014364 NP_688549.1 CDS brnQ-1 NC_004116.1 1565281 1566618 R identified by match to TIGR protein family HMM TIGR00796; branched-chain amino acid transport system II carrier protein complement(1565281..1566618) Streptococcus agalactiae 2603V/R 1014365 NP_688550.1 CDS metG NC_004116.1 1566814 1568811 R methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content; methionyl-tRNA synthetase complement(1566814..1568811) Streptococcus agalactiae 2603V/R 1014366 NP_688551.1 CDS tehB NC_004116.1 1568954 1569829 D with TehA confers resistance to tellurite; tellurite resistance protein TehB 1568954..1569829 Streptococcus agalactiae 2603V/R 1014367 NP_688552.1 CDS SAG1559 NC_004116.1 1569987 1570682 R similar to OMNI:NTL01SPL0310; identified by sequence similarity; hypothetical protein complement(1569987..1570682) Streptococcus agalactiae 2603V/R 1014368 NP_688553.1 CDS SAG1560 NC_004116.1 1570697 1570819 R hypothetical protein complement(1570697..1570819) Streptococcus agalactiae 2603V/R 1014369 NP_688554.1 CDS SAG1561 NC_004116.1 1571018 1572235 D PTS system transporter subunit IIC 1571018..1572235 Streptococcus agalactiae 2603V/R 1014370 NP_688555.1 CDS SAG1562 NC_004116.1 1572219 1573061 D hypothetical protein 1572219..1573061 Streptococcus agalactiae 2603V/R 1014371 NP_688556.1 CDS exoA NC_004116.1 1573138 1573965 D identified by match to PFAM protein family HMM PF01260; In Gram negative bacteria, the apparent functional equivalent is known as exodeoxyribonuclease III (xth).; exodeoxyribonuclease 1573138..1573965 Streptococcus agalactiae 2603V/R 1014372 NP_688557.1 CDS SAG1564 NC_004116.1 1574005 1574361 R hypothetical protein complement(1574005..1574361) Streptococcus agalactiae 2603V/R 1014373 NP_688558.1 CDS ogt NC_004116.1 1574363 1574839 R identified by match to PFAM protein family HMM PF01035; methylated-DNA--protein-cysteine S-methyltransferase complement(1574363..1574839) Streptococcus agalactiae 2603V/R 1014374 NP_688559.1 CDS SAG1566 NC_004116.1 1574894 1576075 R identified by match to PFAM protein family HMM PF01842; D-isomer specific 2-hydroxyacid dehydrogenase family protein complement(1574894..1576075) Streptococcus agalactiae 2603V/R 1014375 NP_688560.1 CDS SAG1567 NC_004116.1 1576138 1576686 R identified by match to PFAM protein family HMM PF00583; acetyltransferase complement(1576138..1576686) Streptococcus agalactiae 2603V/R 1014376 NP_688561.1 CDS SAG1569 NC_004116.1 1577979 1578614 D similar to SP:P46719; identified by sequence similarity; copper homeostasis protein CutC 1577979..1578614 Streptococcus agalactiae 2603V/R 1014378 NP_688562.1 CDS SAG1570 NC_004116.1 1578658 1578762 R hypothetical protein complement(1578658..1578762) Streptococcus agalactiae 2603V/R 1014379 NP_688563.1 CDS SAG1571 NC_004116.1 1578747 1578908 D hypothetical protein 1578747..1578908 Streptococcus agalactiae 2603V/R 1014380 NP_688564.1 CDS SAG1572 NC_004116.1 1578884 1579747 R identified by match to PFAM protein family HMM PF00590; tetrapyrrole methylase family protein complement(1578884..1579747) Streptococcus agalactiae 2603V/R 1014381 NP_688565.1 CDS SAG1573 NC_004116.1 1579753 1580079 R in Bacillus subtilis this protein is involved in the negative regulation of DNA replication initiation; interacts with DnaN and DnaA; DNA replication intiation control protein YabA complement(1579753..1580079) Streptococcus agalactiae 2603V/R 1014382 NP_688566.1 CDS SAG1574 NC_004116.1 1580109 1580972 R catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the delta' subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA.; DNA polymerase III subunit delta' complement(1580109..1580972) Streptococcus agalactiae 2603V/R 1014383 NP_688567.1 CDS tmk NC_004116.1 1580992 1581627 R catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to thymidine monophosphate (dTMP) to form thymidine diphosphate (dTDP); thymidylate kinase complement(1580992..1581627) Streptococcus agalactiae 2603V/R 1014384 NP_688568.1 CDS SAG1577 NC_004116.1 1583268 1583927 R identified by match to PFAM protein family HMM PF00571; AcuB family protein complement(1583268..1583927) Streptococcus agalactiae 2603V/R 1014386 NP_688569.1 CDS livF NC_004116.1 1583946 1584656 R identified by match to PFAM protein family HMM PF00005; branched-chain amino acid ABC transporter ATP-binding protein complement(1583946..1584656) Streptococcus agalactiae 2603V/R 1014387 NP_688570.1 CDS livG NC_004116.1 1584656 1585420 R identified by match to PFAM protein family HMM PF00005; branched-chain amino acid ABC transporter ATP-binding protein complement(1584656..1585420) Streptococcus agalactiae 2603V/R 1014388 NP_688571.1 CDS SAG1580 NC_004116.1 1585421 1586374 R identified by match to PFAM protein family HMM PF02653; branched-chain amino acid ABC transporter permease complement(1585421..1586374) Streptococcus agalactiae 2603V/R 1014389 NP_688572.1 CDS livH NC_004116.1 1586377 1587246 R identified by match to PFAM protein family HMM PF02653; branched-chain amino acid ABC transporter permease complement(1586377..1587246) Streptococcus agalactiae 2603V/R 1014390 NP_688573.1 CDS SAG1582 NC_004116.1 1587352 1588518 R branched-chain amino acid ABC transporter substrate-binding protein complement(1587352..1588518) Streptococcus agalactiae 2603V/R 1014391 NP_688574.1 CDS SAG1583 NC_004116.1 1588673 1588918 R hypothetical protein complement(1588673..1588918) Streptococcus agalactiae 2603V/R 1014392 NP_688575.1 CDS SAG1584 NC_004116.1 1589092 1590225 R identified by match to PFAM protein family HMM PF01609; IS1548 transposase complement(1589092..1590225) Streptococcus agalactiae 2603V/R 1014393 NP_688576.1 CDS clpP NC_004116.1 1590344 1590934 R hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates; ATP-dependent Clp protease proteolytic subunit complement(1590344..1590934) Streptococcus agalactiae 2603V/R 1014394 NP_688577.1 CDS upp NC_004116.1 1591059 1591688 R Catalyzes the formation of uracil and 5-phospho-alpha-D-ribosy 1-diphosphate from UMP and diphosphate; uracil phosphoribosyltransferase complement(1591059..1591688) Streptococcus agalactiae 2603V/R 1014395 NP_688578.1 CDS SAG1587 NC_004116.1 1591798 1592967 R identified by match to PFAM protein family HMM PF00155; class I aminotransferase complement(1591798..1592967) Streptococcus agalactiae 2603V/R 1014396 NP_688579.1 CDS SAG1588 NC_004116.1 1593103 1593651 R identified by match to PFAM protein family HMM PF00588; RNA methyltransferase complement(1593103..1593651) Streptococcus agalactiae 2603V/R 1014397 NP_688580.1 CDS SAG1589 NC_004116.1 1593824 1595176 R identified by match to PFAM protein family HMM PF00324; amino acid permease complement(1593824..1595176) Streptococcus agalactiae 2603V/R 1014398 NP_688581.1 CDS trkA NC_004116.1 1595382 1596731 D involved in potassium uptake; found to be peripherally associated with the inner membrane in Escherichia coli; contains an NAD-binding domain; potassium transporter peripheral membrane protein 1595382..1596731 Streptococcus agalactiae 2603V/R 1014399 NP_688582.1 CDS SAG1591 NC_004116.1 1596748 1598175 D identified by match to PFAM protein family HMM PF02386; cation uptake protein 1596748..1598175 Streptococcus agalactiae 2603V/R 1014400 NP_688583.1 CDS SAG1592 NC_004116.1 1598199 1598450 R hypothetical protein complement(1598199..1598450) Streptococcus agalactiae 2603V/R 1014401 NP_688584.1 CDS rluB NC_004116.1 1598450 1599172 R identified by match to PFAM protein family HMM PF00849; ribosomal large subunit pseudouridine synthase B complement(1598450..1599172) Streptococcus agalactiae 2603V/R 1014402 NP_688585.1 CDS scpB NC_004116.1 1599162 1599746 R functions during chromosome segregation; may form a condensin-like structure with SMC and ScpA; forms a homodimer; segregation and condensation protein B complement(1599162..1599746) Streptococcus agalactiae 2603V/R 1014403 NP_688586.1 CDS scpA NC_004116.1 1599743 1600450 R functions during chromosome segregation; may form a condensin-like structure with SMC and ScpB; segregation and condensation protein A complement(1599743..1600450) Streptococcus agalactiae 2603V/R 1014404 NP_688587.1 CDS xerD NC_004116.1 1600450 1601190 R site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs; site-specific tyrosine recombinase XerD complement(1600450..1601190) Streptococcus agalactiae 2603V/R 1014405 NP_688588.1 CDS SAG1597 NC_004116.1 1601180 1601653 R identified by match to PFAM protein family HMM PF00571; hypothetical protein complement(1601180..1601653) Streptococcus agalactiae 2603V/R 1014406 NP_688589.1 CDS SAG1598 NC_004116.1 1601650 1602171 R hypothetical protein complement(1601650..1602171) Streptococcus agalactiae 2603V/R 1014407 NP_688590.1 CDS SAG1599 NC_004116.1 1602153 1603127 R HAM1-like protein; Rec-dependent growth; RgdB; yggV; it is suspected that this protein functions to remove misincorporated bases such as xanthine or hypoxanthine; deoxyribonucleotide triphosphate pyrophosphatase/unknown domain fusion protein complement(1602153..1603127) Streptococcus agalactiae 2603V/R 1014408 NP_688591.1 CDS murI NC_004116.1 1603124 1603918 R converts L-glutamate to D-glutamate, a component of peptidoglycan; glutamate racemase complement(1603124..1603918) Streptococcus agalactiae 2603V/R 1014409 NP_688592.1 CDS SAG1601 NC_004116.1 1604093 1604332 R hypothetical protein complement(1604093..1604332) Streptococcus agalactiae 2603V/R 1014410 NP_688593.1 CDS SAG1602 NC_004116.1 1604490 1605032 R similar to OMNI:NTL01SPL1119; identified by sequence similarity; hypothetical protein complement(1604490..1605032) Streptococcus agalactiae 2603V/R 1014411 NP_688594.1 CDS SAG1603 NC_004116.1 1605094 1605615 R identified by match to PFAM protein family HMM PF02829; biotin repressor family transcriptional regulator complement(1605094..1605615) Streptococcus agalactiae 2603V/R 1014412 NP_688595.1 CDS SAG1604 NC_004116.1 1605683 1606372 R identified by match to PFAM protein family HMM PF01027; hypothetical protein complement(1605683..1606372) Streptococcus agalactiae 2603V/R 1014413 NP_688596.1 CDS SAG1605 NC_004116.1 1606395 1606898 R hypothetical protein complement(1606395..1606898) Streptococcus agalactiae 2603V/R 1014414 NP_688597.1 CDS SAG1606 NC_004116.1 1606936 1607679 R identified by match to PFAM protein family HMM PF00588; RNA methyltransferase complement(1606936..1607679) Streptococcus agalactiae 2603V/R 1014415 NP_688598.1 CDS SAG1607 NC_004116.1 1607711 1607989 D catalyzes the hydrolysis of acylphosphate; acylphosphatase 1607711..1607989 Streptococcus agalactiae 2603V/R 1014416 NP_688599.1 CDS SAG1608 NC_004116.1 1608074 1609006 D involved in biogenesis of membrane proteins; Firmicutes specific proteins are shorter than other bacterial counterparts and have a signal peptide and lipid attachment site; OxaA-like protein precursor 1608074..1609006 Streptococcus agalactiae 2603V/R 1014417 NP_688600.1 CDS SAG1609 NC_004116.1 1609206 1609871 R identified by match to PFAM protein family HMM PF00528; amino acid ABC transporter permease complement(1609206..1609871) Streptococcus agalactiae 2603V/R 1014418 NP_688601.1 CDS SAG1610 NC_004116.1 1609895 1610752 R identified by match to PFAM protein family HMM PF00497; amino acid ABC transporter substrate-binding protein complement(1609895..1610752) Streptococcus agalactiae 2603V/R 1014419 NP_688602.1 CDS SAG1611 NC_004116.1 1610913 1612373 R catalyzes the hydrolysis of a monocarboxylic acid amid to form a monocarboxylate and ammonia; amidase complement(1610913..1612373) Streptococcus agalactiae 2603V/R 1014420 NP_688603.1 CDS greA NC_004116.1 1612476 1612958 R necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus; transcription elongation factor GreA complement(1612476..1612958) Streptococcus agalactiae 2603V/R 1014421 NP_688604.1 CDS SAG1613 NC_004116.1 1613031 1614833 R hypothetical protein complement(1613031..1614833) Streptococcus agalactiae 2603V/R 1014422 NP_688605.1 CDS SAG1614 NC_004116.1 1614920 1615423 R identified by match to PFAM protein family HMM PF00583; acetyltransferase complement(1614920..1615423) Streptococcus agalactiae 2603V/R 1014423 NP_688606.1 CDS murC NC_004116.1 1615509 1616840 R Catalyzes the formation of UDP-N-acetylmuramoyl-L-alanine from UDP-N-acetylmuramate and L-alanine in peptidoglycan synthesis; UDP-N-acetylmuramate--L-alanine ligase complement(1615509..1616840) Streptococcus agalactiae 2603V/R 1014424 NP_688607.1 CDS SAG1616 NC_004116.1 1616850 1617467 R hypothetical protein complement(1616850..1617467) Streptococcus agalactiae 2603V/R 1014425 NP_688608.1 CDS SAG1617 NC_004116.1 1617472 1617570 R hypothetical protein complement(1617472..1617570) Streptococcus agalactiae 2603V/R 1014426 NP_688609.1 CDS SAG1618 NC_004116.1 1617632 1620730 R identified by match to PFAM protein family HMM PF00176; The product of this gene was detected by Western blot analysis. For details on the method see Tettelin et al. 2002.; Snf2 family protein complement(1617632..1620730) Streptococcus agalactiae 2603V/R 1014427 NP_688610.1 CDS SAG1619 NC_004116.1 1620893 1622026 R identified by match to PFAM protein family HMM PF01609; IS1548 transposase complement(1620893..1622026) Streptococcus agalactiae 2603V/R 1014428 NP_688611.1 CDS engA NC_004116.1 1622211 1623521 R EngA; essential Neisserial GTPase; synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains; GTP-binding protein EngA complement(1622211..1623521) Streptococcus agalactiae 2603V/R 1014429 NP_688612.1 CDS dnaI NC_004116.1 1623569 1624471 R Primosomal protein that may act to load helicase DnaC during DNA replication; primosomal protein DnaI complement(1623569..1624471) Streptococcus agalactiae 2603V/R 1014430 NP_688613.1 CDS SAG1622 NC_004116.1 1624468 1625643 R hypothetical protein complement(1624468..1625643) Streptococcus agalactiae 2603V/R 1014431 NP_688614.1 CDS nrdR NC_004116.1 1625643 1626122 R NrdR family transcriptional regulator complement(1625643..1626122) Streptococcus agalactiae 2603V/R 1014432 NP_688615.1 CDS csrS NC_004116.1 1626271 1627776 R identified by match to PFAM protein family HMM PF00512; sensor histidine kinase CsrS complement(1626271..1627776) Streptococcus agalactiae 2603V/R 1014433 NP_688616.1 CDS csrR NC_004116.1 1627766 1628455 R identified by match to PFAM protein family HMM PF00072; DNA-binding response regulator CsrR complement(1627766..1628455) Streptococcus agalactiae 2603V/R 1014434 NP_688617.1 CDS SAG1626 NC_004116.1 1628690 1629223 R hypothetical protein complement(1628690..1629223) Streptococcus agalactiae 2603V/R 1014435 NP_688618.1 CDS htpX NC_004116.1 1629328 1630218 R metalloprotease; heat shock protein HtpX complement(1629328..1630218) Streptococcus agalactiae 2603V/R 1014436 NP_688619.1 CDS lemA NC_004116.1 1630239 1630793 R similar to OMNI:SP1284; identified by sequence similarity; hypothetical protein complement(1630239..1630793) Streptococcus agalactiae 2603V/R 1014437 NP_688620.1 CDS gidB NC_004116.1 1630921 1631634 D glucose-inhibited division protein B; SAM-dependent methyltransferase; methylates the N7 position of guanosine in position 527 of 16S rRNA; 16S rRNA methyltransferase GidB 1630921..1631634 Streptococcus agalactiae 2603V/R 1014438 NP_688621.1 CDS SAG1630 NC_004116.1 1631649 1633028 D identified by match to PFAM protein family HMM PF02386; sodium transport family protein 1631649..1633028 Streptococcus agalactiae 2603V/R 1014439 NP_688622.1 CDS SAG1631 NC_004116.1 1633041 1633712 D identified by match to PFAM protein family HMM PF02254; Trk family potassium uptake protein 1633041..1633712 Streptococcus agalactiae 2603V/R 1014440 NP_688623.1 CDS SAG1632 NC_004116.1 1633747 1634577 R identified by match to PFAM protein family HMM PF02361; cobalt transport family protein complement(1633747..1634577) Streptococcus agalactiae 2603V/R 1014441 NP_688624.1 CDS SAG1633 NC_004116.1 1634570 1636246 R identified by match to PFAM protein family HMM PF00005; ABC transporter ATP-binding protein complement(1634570..1636246) Streptococcus agalactiae 2603V/R 1014442 NP_688625.2 CDS SAG1634 NC_004116.1 1636263 1636811 R hypothetical protein complement(1636263..1636811) Streptococcus agalactiae 2603V/R 1014443 NP_688626.1 CDS SAG1635 NC_004116.1 1636980 1638188 R involved in the import of serine and threonine coupled with the import of sodium; serine/threonine transporter SstT complement(1636980..1638188) Streptococcus agalactiae 2603V/R 1014444 NP_688627.1 CDS brnQ-2 NC_004116.1 1638364 1639731 D identified by match to TIGR protein family HMM TIGR00796; branched-chain amino acid transport system II carrier protein 1638364..1639731 Streptococcus agalactiae 2603V/R 1014445 NP_688628.1 CDS adh NC_004116.1 1639845 1640900 D identified by match to PFAM protein family HMM PF00107; zinc-containing alcohol dehydrogenase 1639845..1640900 Streptococcus agalactiae 2603V/R 1014446 NP_688629.1 CDS SAG1638 NC_004116.1 1640949 1641641 R identified by match to PFAM protein family HMM PF00528; ABC transporter permease complement(1640949..1641641) Streptococcus agalactiae 2603V/R 1014447 NP_688630.1 CDS SAG1639 NC_004116.1 1641638 1642708 R identified by match to PFAM protein family HMM PF00005; ABC transporter ATP-binding protein complement(1641638..1642708) Streptococcus agalactiae 2603V/R 1014448 NP_688631.1 CDS SAG1640 NC_004116.1 1642701 1644077 R identified by match to PFAM protein family HMM PF01546; hypothetical protein complement(1642701..1644077) Streptococcus agalactiae 2603V/R 1014449 NP_688632.1 CDS SAG1641 NC_004116.1 1644211 1645035 R identified by match to PFAM protein family HMM PF03180; The product of this gene was detected by Western blot analysis. For details on the method see Tettelin et al. 2002.; YaeC family protein complement(1644211..1645035) Streptococcus agalactiae 2603V/R 1014450 NP_688633.1 CDS SAG1642 NC_004116.1 1645176 1646009 R identified by match to PFAM protein family HMM PF00497; ABC transporter substrate-binding protein complement(1645176..1646009) Streptococcus agalactiae 2603V/R 1014451 NP_688634.1 CDS SAG1643 NC_004116.1 1646111 1646800 R identified by match to PFAM protein family HMM PF00117; glutamine amidotransferase complement(1646111..1646800) Streptococcus agalactiae 2603V/R 1014452 NP_688635.1 CDS SAG1644 NC_004116.1 1646794 1646907 R hypothetical protein complement(1646794..1646907) Streptococcus agalactiae 2603V/R 1014453 NP_688636.1 CDS SAG1645 NC_004116.1 1646955 1647671 R hypothetical protein complement(1646955..1647671) Streptococcus agalactiae 2603V/R 1014454 NP_688637.1 CDS SAG1646 NC_004116.1 1647697 1647795 R hypothetical protein complement(1647697..1647795) Streptococcus agalactiae 2603V/R 1014455 NP_688638.1 CDS SAG1647 NC_004116.1 1647789 1648775 R similar to DhaK; in Lactococcus lactis this protein froms a stable complex with DhaS and activates transcription of the dha operon in the presence of dihydroxyacetone; DhaKLM operon coactivator DhaQ complement(1647789..1648775) Streptococcus agalactiae 2603V/R 1014456 NP_688639.1 CDS SAG1648 NC_004116.1 1648785 1649321 R TetR family transcriptional regulator complement(1648785..1649321) Streptococcus agalactiae 2603V/R 1014457 NP_688640.1 CDS SAG1649 NC_004116.1 1649385 1649498 D hypothetical protein 1649385..1649498 Streptococcus agalactiae 2603V/R 1014458 NP_688641.1 CDS SAG1650 NC_004116.1 1649495 1650484 D with DhaL and DhaM forms dihydroxyacetone kinase, which is responsible for phosphorylating dihydroxyacetone; DhaK is the dihydroxyacetone binding subunit of the dihydroxyacetone kinase; dihydroxyacetone kinase subunit DhaK 1649495..1650484 Streptococcus agalactiae 2603V/R 1014459 NP_688642.1 CDS SAG1651 NC_004116.1 1650522 1651100 D identified by match to PFAM protein family HMM PF02734; dihydroxyacetone kinase family protein 1650522..1651100 Streptococcus agalactiae 2603V/R 1014460 NP_688643.1 CDS SAG1652 NC_004116.1 1651100 1651474 D PTS system mannnose-specific transporter subunit IIA 1651100..1651474 Streptococcus agalactiae 2603V/R 1014461 NP_688644.1 CDS glpF-2 NC_004116.1 1651484 1652197 D identified by match to PFAM protein family HMM PF00230; glycerol uptake facilitator protein 1651484..1652197 Streptococcus agalactiae 2603V/R 1014462 NP_688645.1 CDS SAG1654 NC_004116.1 1652462 1652866 R hypothetical protein complement(1652462..1652866) Streptococcus agalactiae 2603V/R 1014463 NP_688646.1 CDS SAG1655 NC_004116.1 1653005 1653718 R identified by match to PFAM protein family HMM PF00376; MerR family transcriptional regulator complement(1653005..1653718) Streptococcus agalactiae 2603V/R 1014464 NP_688647.1 CDS SAG1656 NC_004116.1 1653811 1654920 R hypothetical protein complement(1653811..1654920) Streptococcus agalactiae 2603V/R 1014465 NP_688648.1 CDS SAG1657 NC_004116.1 1654917 1655168 R hypothetical protein complement(1654917..1655168) Streptococcus agalactiae 2603V/R 1014466 NP_688649.1 CDS SAG1658 NC_004116.1 1655191 1655925 R hypothetical protein complement(1655191..1655925) Streptococcus agalactiae 2603V/R 1014467 NP_688650.1 CDS SAG1659 NC_004116.1 1655991 1656347 R identified by match to PFAM protein family HMM PF02410; iojap-like protein complement(1655991..1656347) Streptococcus agalactiae 2603V/R 1014468 NP_688651.1 CDS SAG1660 NC_004116.1 1656349 1656870 R identified by match to PFAM protein family HMM PF00857; isochorismatase family protein complement(1656349..1656870) Streptococcus agalactiae 2603V/R 1014469 NP_688652.1 CDS SAG1661 NC_004116.1 1656933 1657520 R hypothetical protein complement(1656933..1657520) Streptococcus agalactiae 2603V/R 1014470 NP_688653.1 CDS nadD NC_004116.1 1657517 1658149 R transfers an adenyl group from ATP to NaMN to form nicotinic acid adenine dinucleotide (NaAD) which is then converted to the ubiquitous compound NAD by NAD synthetase; essential enzyme in bacteria; nicotinic acid mononucleotide adenylyltransferase complement(1657517..1658149) Streptococcus agalactiae 2603V/R 1014471 NP_688654.1 CDS SAG1663 NC_004116.1 1658279 1658596 R hypothetical protein complement(1658279..1658596) Streptococcus agalactiae 2603V/R 1014472 NP_688655.1 CDS SAG1664 NC_004116.1 1658689 1659807 R in Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis; GTP-binding protein YqeH complement(1658689..1659807) Streptococcus agalactiae 2603V/R 1014473 NP_688656.1 CDS SAG1665 NC_004116.1 1659807 1660340 R identified by match to PFAM protein family HMM PF00702; HAD superfamily hydrolase complement(1659807..1660340) Streptococcus agalactiae 2603V/R 1014474 NP_688657.1 CDS SAG1666 NC_004116.1 1660451 1661365 R identified by match to PFAM protein family HMM PF00892; hypothetical protein complement(1660451..1661365) Streptococcus agalactiae 2603V/R 1014475 NP_688658.1 CDS gatB NC_004116.1 1661495 1662937 R allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; aspartyl/glutamyl-tRNA amidotransferase subunit B complement(1661495..1662937) Streptococcus agalactiae 2603V/R 1014476 NP_688659.1 CDS gatA NC_004116.1 1662937 1664403 R allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; aspartyl/glutamyl-tRNA amidotransferase subunit A complement(1662937..1664403) Streptococcus agalactiae 2603V/R 1014477 NP_688660.1 CDS gatC NC_004116.1 1664403 1664705 R allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; some Mycoplasma proteins contain an N-terminal fusion to an unknown domain; aspartyl/glutamyl-tRNA amidotransferase subunit C complement(1664403..1664705) Streptococcus agalactiae 2603V/R 1014478 NP_688661.1 CDS ppdK NC_004116.1 1664843 1667488 R catalyzes the formation of phosphoenolpyruvate from pyruvate; pyruvate phosphate dikinase complement(1664843..1667488) Streptococcus agalactiae 2603V/R 1014479 NP_688662.1 CDS SAG1671 NC_004116.1 1667501 1668331 R similar to OMNI:NTL01BH1376; identified by sequence similarity; The product of this gene was detected by Western blot analysis. For details on the method see Tettelin et al. 2002.; hypothetical protein complement(1667501..1668331) Streptococcus agalactiae 2603V/R 1014480 NP_688663.1 CDS SAG1672 NC_004116.1 1668342 1668854 R identified by match to PFAM protein family HMM PF00571; In pairwise matches, the initiation methionine is located 40 residues upstream from the current start site of this gene; although there is strong sequence similarity, this ORF lacks an initiation codon in that upstream region.; hypothetical protein complement(1668342..1668854) Streptococcus agalactiae 2603V/R 1014481 NP_688664.1 CDS SAG1673 NC_004116.1 1669160 1670125 D converts (S)-3-hydroxybutanoyl-CoA to 3-acetoacetyl-CoA; 3-hydroxybutyryl-CoA dehydrogenase 1669160..1670125 Streptococcus agalactiae 2603V/R 1014482 NP_688665.1 CDS SAG1674 NC_004116.1 1670172 1670720 R identified by match to PFAM protein family HMM PF00857; isochorismatase family protein complement(1670172..1670720) Streptococcus agalactiae 2603V/R 1014483 NP_688666.1 CDS SAG1675 NC_004116.1 1670787 1671572 R CodY; DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase (By similarity). It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor; transcriptional repressor CodY complement(1670787..1671572) Streptococcus agalactiae 2603V/R 1014484 NP_688667.1 CDS SAG1676 NC_004116.1 1671698 1672909 R broad specificity; family IV; in Corynebacterium glutamicum this protein can use glutamate, 2-aminobutyrate, and aspartate as amino donors and pyruvate as the acceptor; aminotransferase complement(1671698..1672909) Streptococcus agalactiae 2603V/R 1014485 NP_688668.1 CDS SAG1677 NC_004116.1 1673176 1673628 D hypothetical protein 1673176..1673628 Streptococcus agalactiae 2603V/R 1014486 NP_688669.1 CDS SAG1678 NC_004116.1 1673684 1675066 R identified by match to PFAM protein family HMM PF00702; HAD superfamily hydrolase complement(1673684..1675066) Streptococcus agalactiae 2603V/R 1014487 NP_688670.1 CDS SAG1679 NC_004116.1 1675135 1676097 D identified by match to PFAM protein family HMM PF00710; asparaginase 1675135..1676097 Streptococcus agalactiae 2603V/R 1014488 NP_688671.1 CDS aroE NC_004116.1 1676132 1677010 R identified by match to PFAM protein family HMM PF01488; shikimate 5-dehydrogenase complement(1676132..1677010) Streptococcus agalactiae 2603V/R 1014489 NP_688672.1 CDS SAG1681 NC_004116.1 1677108 1678022 R identified by match to PFAM protein family HMM PF00248; aldo/keto reductase complement(1677108..1678022) Streptococcus agalactiae 2603V/R 1014490 NP_688673.1 CDS recG NC_004116.1 1678313 1680328 R catalyzes branch migration in Holliday junction intermediates; ATP-dependent DNA helicase RecG complement(1678313..1680328) Streptococcus agalactiae 2603V/R 1014491 NP_688674.1 CDS SAG1683 NC_004116.1 1680408 1681946 R similar to GP:1399011; identified by sequence similarity; hypothetical protein complement(1680408..1681946) Streptococcus agalactiae 2603V/R 1014492 NP_688675.1 CDS alr NC_004116.1 1682039 1683139 R converts L-alanine to D-alanine which is used in cell wall biosynthesis; binds one pyridoxal phosphate per monomer; forms a homodimer; alanine racemase complement(1682039..1683139) Streptococcus agalactiae 2603V/R 1014493 NP_688676.1 CDS acpS NC_004116.1 1683136 1683495 R Catalyzes the formation of holo-ACP, which mediates the essential transfer of acyl fatty acid intermediates during the biosynthesis of fatty acids and lipids; 4'-phosphopantetheinyl transferase complement(1683136..1683495) Streptococcus agalactiae 2603V/R 1014494 NP_688677.1 CDS SAG1686 NC_004116.1 1683520 1684527 R catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, phenylalanine sensitive; phospho-2-dehydro-3-deoxyheptonate aldolase complement(1683520..1684527) Streptococcus agalactiae 2603V/R 1014495 NP_688678.1 CDS secA NC_004116.1 1684653 1687181 R functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond SecA1; SecA2 is not essential and seems to play a role in secretion of a subset of proteins; preprotein translocase subunit SecA complement(1684653..1687181) Streptococcus agalactiae 2603V/R 1014496 NP_688679.1 CDS manA NC_004116.1 1687290 1688237 R identified by match to PFAM protein family HMM PF01238; mannose-6-phosphate isomerase complement(1687290..1688237) Streptococcus agalactiae 2603V/R 1014497 NP_688680.1 CDS scrK NC_004116.1 1688355 1689236 R identified by match to PFAM protein family HMM PF00480; fructokinase complement(1688355..1689236) Streptococcus agalactiae 2603V/R 1014498 NP_688681.1 CDS SAG1690 NC_004116.1 1689304 1691223 R identified by match to PFAM protein family HMM PF00358; PTS system transporter subunit IIABC complement(1689304..1691223) Streptococcus agalactiae 2603V/R 1014499 NP_688682.1 CDS scrB NC_004116.1 1691408 1692847 D identified by match to PFAM protein family HMM PF00251; sucrose-6-phosphate hydrolase 1691408..1692847 Streptococcus agalactiae 2603V/R 1014500 NP_688683.1 CDS scrR NC_004116.1 1692849 1693811 D identified by match to PFAM protein family HMM PF00356; sucrose operon repressor ScrR 1692849..1693811 Streptococcus agalactiae 2603V/R 1014501 NP_688684.1 CDS nusB NC_004116.1 1693898 1694332 R Regulates rRNA biosynthesis by transcriptional antitermination; transcription antitermination protein NusB complement(1693898..1694332) Streptococcus agalactiae 2603V/R 1014502 NP_688685.1 CDS SAG1694 NC_004116.1 1694325 1694714 R hypothetical protein complement(1694325..1694714) Streptococcus agalactiae 2603V/R 1014503 NP_688686.1 CDS efp NC_004116.1 1694803 1695363 R Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA; elongation factor P complement(1694803..1695363) Streptococcus agalactiae 2603V/R 1014504 NP_688687.1 CDS SAG1696 NC_004116.1 1695394 1695510 R hypothetical protein complement(1695394..1695510) Streptococcus agalactiae 2603V/R 1014505 NP_688688.1 CDS SAG1697 NC_004116.1 1696092 1696238 R hypothetical protein complement(1696092..1696238) Streptococcus agalactiae 2603V/R 1014506 NP_688689.1 CDS SAG1698 NC_004116.1 1696291 1696590 R hypothetical protein complement(1696291..1696590) Streptococcus agalactiae 2603V/R 1014507 NP_688690.1 CDS SAG1699 NC_004116.1 1696643 1696735 R hypothetical protein complement(1696643..1696735) Streptococcus agalactiae 2603V/R 1014508 NP_688691.1 CDS SAG1700 NC_004116.1 1697008 1697238 R hypothetical protein complement(1697008..1697238) Streptococcus agalactiae 2603V/R 1014509 NP_688692.1 CDS SAG1701 NC_004116.1 1697251 1697421 R hypothetical protein complement(1697251..1697421) Streptococcus agalactiae 2603V/R 1014510 NP_688693.1 CDS SAG1702 NC_004116.1 1697874 1697999 R hypothetical protein complement(1697874..1697999) Streptococcus agalactiae 2603V/R 1014511 NP_688694.1 CDS SAG1703 NC_004116.1 1698010 1698174 R hypothetical protein complement(1698010..1698174) Streptococcus agalactiae 2603V/R 1014512 NP_688695.1 CDS SAG1704 NC_004116.1 1698476 1698928 R identified by match to PFAM protein family HMM PF00383; cytidine/deoxycytidylate deaminase family protein complement(1698476..1698928) Streptococcus agalactiae 2603V/R 1014513 NP_688696.1 CDS SAG1706 NC_004116.1 1700107 1700823 R hypothetical protein complement(1700107..1700823) Streptococcus agalactiae 2603V/R 1014515 NP_688697.1 CDS SAG1707 NC_004116.1 1700825 1702324 R identified by match to PFAM protein family HMM PF00083; EmrB/QacA family drug resistance transporter complement(1700825..1702324) Streptococcus agalactiae 2603V/R 1014516 NP_688698.1 CDS SAG1708 NC_004116.1 1702412 1702528 R hypothetical protein complement(1702412..1702528) Streptococcus agalactiae 2603V/R 1014517 NP_688699.1 CDS uvrA NC_004116.1 1702660 1705488 R The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate; excinuclease ABC subunit A complement(1702660..1705488) Streptococcus agalactiae 2603V/R 1014518 NP_688700.1 CDS SAG1710 NC_004116.1 1705620 1706291 R hypothetical protein complement(1705620..1706291) Streptococcus agalactiae 2603V/R 1014519 NP_688701.1 CDS SAG1711 NC_004116.1 1706316 1707260 R identified by match to PFAM protein family HMM PF01544; magnesium transporter CorA family protein complement(1706316..1707260) Streptococcus agalactiae 2603V/R 1014520 NP_688702.1 CDS rpsR NC_004116.1 1707430 1707669 R binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit; 30S ribosomal protein S18 complement(1707430..1707669) Streptococcus agalactiae 2603V/R 1014521 NP_688703.1 CDS ssb-3 NC_004116.1 1707714 1708205 R binds to single stranded DNA and may facilitate the binding and interaction of other proteins to DNA; single-stranded DNA-binding protein complement(1707714..1708205) Streptococcus agalactiae 2603V/R 1014522 NP_688704.1 CDS rpsF NC_004116.1 1708217 1708504 R binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21; 30S ribosomal protein S6 complement(1708217..1708504) Streptococcus agalactiae 2603V/R 1014523 NP_688705.1 CDS mutY NC_004116.1 1709598 1710722 D identified by match to PFAM protein family HMM PF00730; A/G-specific adenine glycosylase 1709598..1710722 Streptococcus agalactiae 2603V/R 1014524 NP_688706.1 CDS SAG1716 NC_004116.1 1710899 1711492 D identified by match to PFAM protein family HMM PF01381; Cro/CI family transcriptional regulator 1710899..1711492 Streptococcus agalactiae 2603V/R 1014525 NP_688707.1 CDS trx NC_004116.1 1711538 1711852 R identified by match to PFAM protein family HMM PF00085; thioredoxin complement(1711538..1711852) Streptococcus agalactiae 2603V/R 1014526 NP_688708.1 CDS SAG1718 NC_004116.1 1711933 1712433 R identified by match to PFAM protein family HMM PF01569; PAP2 family protein complement(1711933..1712433) Streptococcus agalactiae 2603V/R 1014527 NP_688709.1 CDS SAG1719 NC_004116.1 1712437 1714776 R identified by match to PFAM protein family HMM PF00488; Function of MutS2 is unknown. It should not be considered a DNA mismatch repair protein. It is likely a DNA mismatch binding protein of unknown cellular function.; MutS2 family protein complement(1712437..1714776) Streptococcus agalactiae 2603V/R 1014528 NP_688710.1 CDS SAG1720 NC_004116.1 1714861 1715403 R hypothetical protein complement(1714861..1715403) Streptococcus agalactiae 2603V/R 1014529 NP_688711.1 CDS SAG1721 NC_004116.1 1715406 1715717 R hypothetical protein complement(1715406..1715717) Streptococcus agalactiae 2603V/R 1014530 NP_688712.1 CDS rnhC NC_004116.1 1715828 1716721 D An endonuclease that specifically degrades the RNA strand of RNA-DNA hybrids; ribonuclease HIII 1715828..1716721 Streptococcus agalactiae 2603V/R 1014531 NP_688713.1 CDS SAG1723 NC_004116.1 1716737 1717330 D identified by match to PFAM protein family HMM PF00461; signal peptidase I 1716737..1717330 Streptococcus agalactiae 2603V/R 1014532 NP_688714.1 CDS SAG1724 NC_004116.1 1717459 1719879 D identified by match to TIGR protein family HMM TIGR01448; helicase 1717459..1719879 Streptococcus agalactiae 2603V/R 1014533 NP_688715.1 CDS SAG1725 NC_004116.1 1719993 1720475 D hypothetical protein 1719993..1720475 Streptococcus agalactiae 2603V/R 1014534 NP_688716.1 CDS dinP NC_004116.1 1720546 1721640 R involved in translesion DNA polymerization with beta clamp of polymerase III; belongs to Y family of polymerases; does not contain proofreading function; DNA polymerase IV complement(1720546..1721640) Streptococcus agalactiae 2603V/R 1014535 NP_688717.1 CDS pflD-2 NC_004116.1 1721825 1724137 D identified by match to PFAM protein family HMM PF01228; formate acetyltransferase 1721825..1724137 Streptococcus agalactiae 2603V/R 1014536 NP_688718.1 CDS SAG1728 NC_004116.1 1724238 1724612 D similar to SP:Q46604; identified by sequence similarity; FMN-binding protein 1724238..1724612 Streptococcus agalactiae 2603V/R 1014537 NP_688719.1 CDS SAG1729 NC_004116.1 1724647 1725576 R hypothetical protein complement(1724647..1725576) Streptococcus agalactiae 2603V/R 1014538 NP_688720.1 CDS SAG1730 NC_004116.1 1725573 1726328 R hypothetical protein complement(1725573..1726328) Streptococcus agalactiae 2603V/R 1014539 NP_688721.1 CDS SAG1731 NC_004116.1 1726453 1727349 D hypothetical protein 1726453..1727349 Streptococcus agalactiae 2603V/R 1014540 NP_688722.1 CDS SAG1732 NC_004116.1 1727428 1728276 R identified by match to PFAM protein family HMM PF00230; glycerol uptake facilitator protein complement(1727428..1728276) Streptococcus agalactiae 2603V/R 1014541 NP_688723.1 CDS SAG1733 NC_004116.1 1728444 1728896 R identified by match to PFAM protein family HMM PF00582; universal stress protein complement(1728444..1728896) Streptococcus agalactiae 2603V/R 1014542 NP_688724.1 CDS SAG1734 NC_004116.1 1728914 1730116 R identified by match to PFAM protein family HMM PF00083; transporter complement(1728914..1730116) Streptococcus agalactiae 2603V/R 1014543 NP_688725.1 CDS SAG1735 NC_004116.1 1730273 1730932 D Crp/Fnr family transcriptional regulator 1730273..1730932 Streptococcus agalactiae 2603V/R 1014544 NP_688726.1 CDS pepX NC_004116.1 1730956 1733241 D catalyzes the removal of N-terminal dipeptides when proline is the penultimate residue; x-prolyl-dipeptidyl aminopeptidase 1730956..1733241 Streptococcus agalactiae 2603V/R 1014545 NP_688727.1 CDS SAG1737 NC_004116.1 1733245 1733604 D hypothetical protein 1733245..1733604 Streptococcus agalactiae 2603V/R 1014546 NP_688728.1 CDS SAG1738 NC_004116.1 1733650 1734630 D identified by match to PFAM protein family HMM PF00348; polyprenyl synthetase 1733650..1734630 Streptococcus agalactiae 2603V/R 1014547 NP_688729.1 CDS cydC NC_004116.1 1734715 1736463 R identified by match to PFAM protein family HMM PF00005; ABC transporter ATP-binding protein complement(1734715..1736463) Streptococcus agalactiae 2603V/R 1014548 NP_688730.1 CDS SAG1740 NC_004116.1 1736456 1738174 R identified by match to PFAM protein family HMM PF00005; ABC transporter ATP-binding protein complement(1736456..1738174) Streptococcus agalactiae 2603V/R 1014549 NP_688731.1 CDS cydB NC_004116.1 1738174 1739193 R identified by match to PFAM protein family HMM PF02322; cytochrome d ubiquinol oxidase, subunit II complement(1738174..1739193) Streptococcus agalactiae 2603V/R 1014550 NP_688732.1 CDS cydA NC_004116.1 1739194 1740621 R identified by match to PFAM protein family HMM PF01654; cytochrome d oxidase subunit I complement(1739194..1740621) Streptococcus agalactiae 2603V/R 1014551 NP_688733.1 CDS SAG1743 NC_004116.1 1740724 1741932 R identified by match to PFAM protein family HMM PF00070; pyridine nucleotide-disulfide oxidoreductase family protein complement(1740724..1741932) Streptococcus agalactiae 2603V/R 1014552 NP_688734.1 CDS SAG1744 NC_004116.1 1741945 1742844 R catalyzes the formation of dimethylmenaquinone from 1,4-dihydroxy-2-naphthoate and octaprenyl diphosphate; 1,4-dihydroxy-2-naphthoate octaprenyltransferase complement(1741945..1742844) Streptococcus agalactiae 2603V/R 1014553 NP_688735.1 CDS SAG1745 NC_004116.1 1743253 1743699 R hypothetical protein complement(1743253..1743699) Streptococcus agalactiae 2603V/R 1014554 NP_688736.1 CDS SAG1746 NC_004116.1 1744352 1744459 R hypothetical protein complement(1744352..1744459) Streptococcus agalactiae 2603V/R 1014555 NP_688737.1 CDS SAG1747 NC_004116.1 1744582 1744881 D hypothetical protein 1744582..1744881 Streptococcus agalactiae 2603V/R 1014556 NP_688738.1 CDS cfa NC_004116.1 1745041 1746231 D identified by match to PFAM protein family HMM PF02353; cyclopropane-fatty-acyl-phospholipid synthase 1745041..1746231 Streptococcus agalactiae 2603V/R 1014557 NP_688739.1 CDS SAG1749 NC_004116.1 1746301 1747026 R identified by match to PFAM protein family HMM PF00376; MerR family transcriptional regulator complement(1746301..1747026) Streptococcus agalactiae 2603V/R 1014558 NP_688740.1 CDS SAG1750 NC_004116.1 1747153 1747740 R 3'-5' exonuclease of DNA polymerase III; DNA polymerase III subunit epsilon complement(1747153..1747740) Streptococcus agalactiae 2603V/R 1014559 NP_688741.1 CDS SAG1751 NC_004116.1 1747784 1748320 R hypothetical protein complement(1747784..1748320) Streptococcus agalactiae 2603V/R 1014560 NP_688742.1 CDS SAG1752 NC_004116.1 1748455 1749627 D hypothetical protein 1748455..1749627 Streptococcus agalactiae 2603V/R 1014561 NP_688743.1 CDS SAG1753 NC_004116.1 1749671 1750453 R hypothetical protein complement(1749671..1750453) Streptococcus agalactiae 2603V/R 1014562 NP_688744.1 CDS rpsN NC_004116.1 1750612 1750881 D located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group do not appear to have the zinc-binding motif; 30S ribosomal protein S14 1750612..1750881 Streptococcus agalactiae 2603V/R 1014563 NP_688745.1 CDS SAG1755 NC_004116.1 1751089 1751205 D hypothetical protein 1751089..1751205 Streptococcus agalactiae 2603V/R 1014564 NP_688746.1 CDS SAG1756 NC_004116.1 1751242 1752267 R hypothetical protein complement(1751242..1752267) Streptococcus agalactiae 2603V/R 1014565 NP_688747.1 CDS SAG1757 NC_004116.1 1752387 1753397 R in most organisms, only the N-terminal domain is present in a single polypeptide; in some archaea this domain is fused to a kinase domain; this gene is essential for growth in Escherichia coli and Bacillus subtilis; the secreted glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins; the Pyrococcus structure shows DNA-binding properties, iron-binding, ATP-binding, and AP endonuclease activity; DNA-binding/iron metalloprotein/AP endonuclease complement(1752387..1753397) Streptococcus agalactiae 2603V/R 1014566 NP_688748.1 CDS SAG1758 NC_004116.1 1753473 1753880 R identified by match to PFAM protein family HMM PF00583; ribosomal-protein-alanine acetyltransferase complement(1753473..1753880) Streptococcus agalactiae 2603V/R 1014567 NP_688749.1 CDS SAG1759 NC_004116.1 1753882 1754574 R The product of this gene was detected by Western blot analysis. For details on the method see Tettelin et al. 2002.; hypothetical protein complement(1753882..1754574) Streptococcus agalactiae 2603V/R 1014568 NP_688750.1 CDS SAG1760 NC_004116.1 1754753 1754983 D hypothetical protein 1754753..1754983 Streptococcus agalactiae 2603V/R 1014569 NP_688751.1 CDS SAG1761 NC_004116.1 1755037 1756716 D identified by match to PFAM protein family HMM PF00753; metallo-beta-lactamase superfamily protein 1755037..1756716 Streptococcus agalactiae 2603V/R 1014570 NP_688752.1 CDS SAG1762 NC_004116.1 1756874 1757383 R hypothetical protein complement(1756874..1757383) Streptococcus agalactiae 2603V/R 1014571 NP_688753.1 CDS glnA NC_004116.1 1757531 1758877 R identified by match to PFAM protein family HMM PF00120; glutamine synthetase, type I complement(1757531..1758877) Streptococcus agalactiae 2603V/R 1014572 NP_688754.1 CDS glnR NC_004116.1 1758911 1759282 R identified by match to PFAM protein family HMM PF00376; GlnR family transcriptional regulator complement(1758911..1759282) Streptococcus agalactiae 2603V/R 1014573 NP_688755.1 CDS SAG1765 NC_004116.1 1759362 1759901 R hypothetical protein complement(1759362..1759901) Streptococcus agalactiae 2603V/R 1014574 NP_688756.1 CDS pgk NC_004116.1 1760164 1761360 R Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway; phosphoglycerate kinase complement(1760164..1761360) Streptococcus agalactiae 2603V/R 1014575 NP_688757.1 CDS SAG1767 NC_004116.1 1761495 1762364 R similar to GP:1944618; identified by sequence similarity; acid phosphatase complement(1761495..1762364) Streptococcus agalactiae 2603V/R 1014576 NP_688758.1 CDS gap NC_004116.1 1762573 1763583 R catalyzes the formation of 3-phospho-D-glyceroyl phosphate from D-glyceraldehyde 3-phosphate; glyceraldehyde-3-phosphate dehydrogenase complement(1762573..1763583) Streptococcus agalactiae 2603V/R 1014577 NP_688759.1 CDS fusA NC_004116.1 1763787 1765865 R EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene; elongation factor G complement(1763787..1765865) Streptococcus agalactiae 2603V/R 1014578 NP_688760.1 CDS rpsG NC_004116.1 1766020 1766490 R binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit; 30S ribosomal protein S7 complement(1766020..1766490) Streptococcus agalactiae 2603V/R 1014579 NP_688761.1 CDS rpsL NC_004116.1 1766512 1766925 R interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance; 30S ribosomal protein S12 complement(1766512..1766925) Streptococcus agalactiae 2603V/R 1014580 NP_688762.1 CDS purR NC_004116.1 1767144 1767956 R identified by match to PFAM protein family HMM PF00156; pur operon repressor complement(1767144..1767956) Streptococcus agalactiae 2603V/R 1014581 NP_688763.1 CDS SAG1773 NC_004116.1 1768053 1768994 R identified by match to PFAM protein family HMM PF01966; HD domain-containing protein complement(1768053..1768994) Streptococcus agalactiae 2603V/R 1014582 NP_688764.1 CDS SAG1774 NC_004116.1 1768984 1770258 R hypothetical protein complement(1768984..1770258) Streptococcus agalactiae 2603V/R 1014583 NP_688765.1 CDS SAG1775 NC_004116.1 1770260 1770892 R hypothetical protein complement(1770260..1770892) Streptococcus agalactiae 2603V/R 1014584 NP_688766.1 CDS rpe NC_004116.1 1770885 1771547 R catalyzes the interconversion of D-ribulose 5-phosphate to xylulose 5-phosphate; ribulose-phosphate 3-epimerase complement(1770885..1771547) Streptococcus agalactiae 2603V/R 1014585 NP_688767.1 CDS SAG1777 NC_004116.1 1771554 1772426 R EngC; RsgA; CpgA; circularly permuted GTPase; ribosome small subunit-dependent GTPase A; has the pattern G4-G1-G3 as opposed to other GTPases; interacts strongly with 30S ribosome which stimulates GTPase activity; ribosome-associated GTPase complement(1771554..1772426) Streptococcus agalactiae 2603V/R 1014586 NP_688768.1 CDS SAG1778 NC_004116.1 1772582 1773433 R similar to GB:D28496 SP:P36999 PID:460699 GB:U00096 PID:1736466; identified by sequence similarity; rRNA (guanine-N1-)-methyltransferase complement(1772582..1773433) Streptococcus agalactiae 2603V/R 1014587 NP_688769.1 CDS ksgA NC_004116.1 1773437 1774309 R catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin; dimethyladenosine transferase complement(1773437..1774309) Streptococcus agalactiae 2603V/R 1014588 NP_688770.1 CDS SAG1780 NC_004116.1 1774389 1774880 R hypothetical protein complement(1774389..1774880) Streptococcus agalactiae 2603V/R 1014589 NP_688771.1 CDS SAG1781 NC_004116.1 1774899 1775459 R identified by match to PFAM protein family HMM PF01751; primase-like protein complement(1774899..1775459) Streptococcus agalactiae 2603V/R 1014590 NP_688772.1 CDS SAG1782 NC_004116.1 1775446 1776228 R identified by match to PFAM protein family HMM PF01026; TatD family deoxyribonuclease complement(1775446..1776228) Streptococcus agalactiae 2603V/R 1014591 NP_688773.1 CDS SAG1783 NC_004116.1 1776410 1776682 R hypothetical protein complement(1776410..1776682) Streptococcus agalactiae 2603V/R 1014592 NP_688774.1 CDS SAG1784 NC_004116.1 1776701 1777093 R hypothetical protein complement(1776701..1777093) Streptococcus agalactiae 2603V/R 1014593 NP_688775.1 CDS SAG1785 NC_004116.1 1777084 1778376 R hypothetical protein complement(1777084..1778376) Streptococcus agalactiae 2603V/R 1014594 NP_688776.1 CDS SAG1786 NC_004116.1 1778376 1778768 R identified by Glimmer2; The product of this gene was detected by Western blot analysis. For details on the method see Tettelin et al. 2002.; hypothetical protein complement(1778376..1778768) Streptococcus agalactiae 2603V/R 1014595 NP_688777.1 CDS dltD NC_004116.1 1778943 1780205 R similar to OMNI:SP2173; identified by sequence similarity; dltD protein complement(1778943..1780205) Streptococcus agalactiae 2603V/R 1014596 NP_688778.1 CDS dltC NC_004116.1 1780198 1780437 R D-alanyl carrier protein subunit; involved in the incorporation of D-alanine into membrane-associated D-alanyl-lipoteichoic acid; D-alanyl carrier protein is the acceptor of activated D-alanine which it donates to a membrane acceptor(D-alanyl transferase) for incorporation into membrane lipoteichoic acid; D-alanine--poly(phosphoribitol) ligase subunit 2 complement(1780198..1780437) Streptococcus agalactiae 2603V/R 1014597 NP_688779.1 CDS dltB NC_004116.1 1780452 1781717 R similar to OMNI:SP2175; identified by sequence similarity; dltB protein complement(1780452..1781717) Streptococcus agalactiae 2603V/R 1014598 NP_688780.1 CDS dltA NC_004116.1 1781714 1783249 R transfers D-alanine to the D-alanyl carrier protein during the incorporation of D-alanine into lipoteichoic acid; D-alanine--poly(phosphoribitol) ligase subunit 1 complement(1781714..1783249) Streptococcus agalactiae 2603V/R 1014599 NP_688781.1 CDS SAG1791 NC_004116.1 1783395 1784582 R identified by match to PFAM protein family HMM PF00512; sensor histidine kinase complement(1783395..1784582) Streptococcus agalactiae 2603V/R 1014600 NP_688782.1 CDS SAG1792 NC_004116.1 1784582 1785256 R identified by match to PFAM protein family HMM PF00072; DNA-binding response regulator complement(1784582..1785256) Streptococcus agalactiae 2603V/R 1014601 NP_688783.1 CDS rpmH NC_004116.1 1785612 1785746 R in Escherichia coli transcription of this gene is enhanced by polyamines; 50S ribosomal protein L34 complement(1785612..1785746) Streptococcus agalactiae 2603V/R 1014602 NP_688784.1 CDS SAG1794 NC_004116.1 1785930 1787285 R similar to OMNI:NTL01BH3953; identified by sequence similarity; hypothetical protein complement(1785930..1787285) Streptococcus agalactiae 2603V/R 1014603 NP_688785.1 CDS SAG1795 NC_004116.1 1787517 1788683 D identified by match to PFAM protein family HMM PF00665; IS30 family transposase 1787517..1788683 Streptococcus agalactiae 2603V/R 1014604 NP_688786.1 CDS SAG1796 NC_004116.1 1789082 1790809 R identified by match to PFAM protein family HMM PF00528; amino acid ABC transporter permease complement(1789082..1790809) Streptococcus agalactiae 2603V/R 1014605 NP_688787.1 CDS SAG1797 NC_004116.1 1790828 1792051 R identified by match to PFAM protein family HMM PF00005; amino acid ABC transporter ATP-binding protein complement(1790828..1792051) Streptococcus agalactiae 2603V/R 1014606 NP_688788.1 CDS SAG1798 NC_004116.1 1792194 1792313 D hypothetical protein 1792194..1792313 Streptococcus agalactiae 2603V/R 1014607 NP_688789.1 CDS xfp NC_004116.1 1792428 1794806 R similar to SP:Q9AEM9; identified by sequence similarity; phosphoketolase complement(1792428..1794806) Streptococcus agalactiae 2603V/R 1014608 NP_688790.1 CDS SAG1800 NC_004116.1 1794896 1795987 R L-ascorbate 6-phosphate lactonase complement(1794896..1795987) Streptococcus agalactiae 2603V/R 1014609 NP_688791.1 CDS SAG1801 NC_004116.1 1796304 1797983 R identified by match to PFAM protein family HMM PF00874; BglG family transcriptional antiterminator complement(1796304..1797983) Streptococcus agalactiae 2603V/R 1014610 NP_688792.1 CDS SAG1802 NC_004116.1 1798049 1798810 R hypothetical protein complement(1798049..1798810) Streptococcus agalactiae 2603V/R 1014611 NP_688793.1 CDS SAG1803 NC_004116.1 1798830 1800347 R identified by match to PFAM protein family HMM PF00370; carbohydrate kinase complement(1798830..1800347) Streptococcus agalactiae 2603V/R 1014612 NP_688794.1 CDS SAG1804 NC_004116.1 1800413 1801402 R hypothetical protein complement(1800413..1801402) Streptococcus agalactiae 2603V/R 1014613 NP_688795.1 CDS SAG1805 NC_004116.1 1801424 1802875 R PTS system transporter subunit IIC complement(1801424..1802875) Streptococcus agalactiae 2603V/R 1014614 NP_688796.1 CDS SAG1806 NC_004116.1 1802973 1803929 R identified by match to PFAM protein family HMM PF00389; glyoxylate reductase, NADH-dependent complement(1802973..1803929) Streptococcus agalactiae 2603V/R 1014615 NP_688797.1 CDS SAG1807 NC_004116.1 1803948 1804967 R hypothetical protein complement(1803948..1804967) Streptococcus agalactiae 2603V/R 1014616 NP_688798.1 CDS SAG1808 NC_004116.1 1805202 1806185 R identified by match to PFAM protein family HMM PF00356; LacI family sugar-binding transcriptional regulator complement(1805202..1806185) Streptococcus agalactiae 2603V/R 1014617 NP_688799.1 CDS SAG1809 NC_004116.1 1806349 1806996 R similar to novel fructose-6-phosphate aldolase from Escherichia coli; enzyme from Methanocaldococcus janaschii shows transaldolase activity; translaldolase complement(1806349..1806996) Streptococcus agalactiae 2603V/R 1014618 NP_688800.1 CDS araD NC_004116.1 1807007 1807723 R catalyzes the formation of D-xylulose 5-phosphate from L-ribulose 5-phosphate in the L-arabinose and L-ascorbate degradation pathways; L-ribulose-5-phosphate 4-epimerase complement(1807007..1807723) Streptococcus agalactiae 2603V/R 1014619 NP_688801.1 CDS SAG1811 NC_004116.1 1807725 1808588 R L-xylulose 5-phosphate 3-epimerase activity not yet demonstrated; may be involved in the utilization of 2,3-diketo-L-gulonate; L-xylulose 5-phosphate 3-epimerase complement(1807725..1808588) Streptococcus agalactiae 2603V/R 1014620 NP_688802.1 CDS ulaD NC_004116.1 1808592 1809257 R catalyzes the formation of L-xylulose-5-phosphate from 3-keto-L-gulonate-6-phosphate in anaerobic L-ascorbate utilization; 3-keto-L-gulonate-6-phosphate decarboxylase complement(1808592..1809257) Streptococcus agalactiae 2603V/R 1014621 NP_688803.1 CDS SAG1813 NC_004116.1 1809370 1809855 R identified by match to PFAM protein family HMM PF00359; PTS system transporter subunit IIA complement(1809370..1809855) Streptococcus agalactiae 2603V/R 1014622 NP_688804.1 CDS SAG1814 NC_004116.1 1809922 1810200 R similar to OMNI:SP2037; identified by sequence similarity; PTS system transporter subunit IIB complement(1809922..1810200) Streptococcus agalactiae 2603V/R 1014623 NP_688805.1 CDS ulaA NC_004116.1 1810228 1811667 R membrane component; functions with enzymes IIB (sgaB; ulaB) and IIA (sgaA; ulaC) enzyme I and HPr for anaerobic utilization and uptake of L-ascorbate; sgaTBA are regulated by yifQ as well as Crp and Fnr; PTS system ascorbate-specific transporter subunit IIC complement(1810228..1811667) Streptococcus agalactiae 2603V/R 1014624 NP_688806.1 CDS SAG1816 NC_004116.1 1811835 1812452 R hypothetical protein complement(1811835..1812452) Streptococcus agalactiae 2603V/R 1014625 NP_688807.1 CDS SAG1817 NC_004116.1 1812611 1813084 D hypothetical protein 1812611..1813084 Streptococcus agalactiae 2603V/R 1014626 NP_688808.1 CDS purA NC_004116.1 1813107 1814399 R catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis; adenylosuccinate synthetase complement(1813107..1814399) Streptococcus agalactiae 2603V/R 1014627 NP_688809.1 CDS pfoR NC_004116.1 1814769 1815791 R identified by sequence similarity; perfringolysin O regulator protein complement(1814769..1815791) Streptococcus agalactiae 2603V/R 1014628 NP_688810.1 CDS SAG1820 NC_004116.1 1816153 1816827 D hypothetical protein 1816153..1816827 Streptococcus agalactiae 2603V/R 1014629 NP_688811.1 CDS SAG1821 NC_004116.1 1816997 1819249 D Synthesizes glutathione from L-glutamate and L-cysteine via gamma-L-glutamyl-L-cysteine; bifunctional glutamate--cysteine ligase/glutathione synthetase 1816997..1819249 Streptococcus agalactiae 2603V/R 1014630 NP_688812.1 CDS SAG1822 NC_004116.1 1819373 1820191 D similar to OMNI:NTL01SPL0121; identified by sequence similarity; The product of this gene was detected by Western blot analysis. For details on the method see Tettelin et al. 2002.; hypothetical protein 1819373..1820191 Streptococcus agalactiae 2603V/R 1014631 NP_688813.1 CDS SAG1823 NC_004116.1 1820188 1821444 D similar to OMNI:NTL01SPL0120; identified by sequence similarity; The product of this gene was detected by Western blot analysis. For details on the method see Tettelin et al. 2002.; hypothetical protein 1820188..1821444 Streptococcus agalactiae 2603V/R 1014632 NP_688814.1 CDS hslO NC_004116.1 1821584 1822459 D becomes active under oxidative stress; four conserved cysteines bind a zinc atom when they are in the reduced state and the enzyme is inactive; oxidative stress results in oxidized cysteines, release of zinc, and binding of Hsp33 to aggregation-prone proteins; forms dimers and higher order oligomers; heat shock protein 33 1821584..1822459 Streptococcus agalactiae 2603V/R 1014633 NP_688815.1 CDS SAG1825 NC_004116.1 1822443 1823420 D identified by match to PFAM protein family HMM PF01207; NifR3/Smm1 family protein 1822443..1823420 Streptococcus agalactiae 2603V/R 1014634 NP_688816.1 CDS SAG1826 NC_004116.1 1823541 1824182 D identified by match to PFAM protein family HMM PF01712; deoxynucleoside kinase family protein 1823541..1824182 Streptococcus agalactiae 2603V/R 1014635 NP_688817.1 CDS pat NC_004116.1 1824196 1824687 D identified by match to PFAM protein family HMM PF00583; phosphinothricin N-acetyltransferase 1824196..1824687 Streptococcus agalactiae 2603V/R 1014636 NP_688818.1 CDS SAG1828 NC_004116.1 1824907 1827354 R identified by match to PFAM protein family HMM PF00004; ATP-dependent Clp protease, ATP-binding subunit complement(1824907..1827354) Streptococcus agalactiae 2603V/R 1014637 NP_688819.1 CDS ctsR NC_004116.1 1827351 1827815 R similar to GB:D26185 SP:P37568 PID:467471 GB:AL009126; identified by sequence similarity; CtsR family transcriptional regulator complement(1827351..1827815) Streptococcus agalactiae 2603V/R 1014638 NP_688820.1 CDS SAG1830 NC_004116.1 1827988 1828449 D hypothetical protein 1827988..1828449 Streptococcus agalactiae 2603V/R 1014639 NP_688821.1 CDS tsf NC_004116.1 1828608 1829648 R EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu; elongation factor Ts complement(1828608..1829648) Streptococcus agalactiae 2603V/R 1014640 NP_688822.1 CDS rpsB NC_004116.1 1829742 1830512 R one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit; 30S ribosomal protein S2 complement(1829742..1830512) Streptococcus agalactiae 2603V/R 1014641 NP_688823.1 CDS ahpC NC_004116.1 1830789 1831349 D identified by match to PFAM protein family HMM PF00578; alkyl hydroperoxide reductase 1830789..1831349 Streptococcus agalactiae 2603V/R 1014642 NP_688824.1 CDS ahpF NC_004116.1 1831367 1832899 D identified by match to PFAM protein family HMM PF00070; alkyl hydroperoxide reductase 1831367..1832899 Streptococcus agalactiae 2603V/R 1014643 NP_688825.1 CDS SAG1835 NC_004116.1 1833318 1833722 R hypothetical protein complement(1833318..1833722) Streptococcus agalactiae 2603V/R 1014645 NP_688826.1 CDS SAG1836 NC_004116.1 1833783 1833968 R hypothetical protein complement(1833783..1833968) Streptococcus agalactiae 2603V/R 1014646 NP_688827.1 CDS SAG1837 NC_004116.1 1834175 1835581 R identified by match to PFAM protein family HMM PF01832; prophage LambdaSa2, lysin complement(1834175..1835581) Streptococcus agalactiae 2603V/R 1014647 NP_688828.1 CDS SAG1838 NC_004116.1 1835585 1835914 R similar to GP:13655626; identified by sequence similarity; prophage LambdaSa2, holin complement(1835585..1835914) Streptococcus agalactiae 2603V/R 1014648 NP_688829.1 CDS SAG1839 NC_004116.1 1835917 1836327 R hypothetical protein complement(1835917..1836327) Streptococcus agalactiae 2603V/R 1014649 NP_688830.1 CDS SAG1840 NC_004116.1 1836362 1836700 R hypothetical protein complement(1836362..1836700) Streptococcus agalactiae 2603V/R 1014650 NP_688831.1 CDS SAG1841 NC_004116.1 1836703 1836933 R similar to PID:1514671; identified by sequence similarity; hypothetical protein complement(1836703..1836933) Streptococcus agalactiae 2603V/R 1014651 NP_688832.1 CDS SAG1842 NC_004116.1 1836950 1840624 R similar to GP:10732859; identified by sequence similarity; PblB is a platelet adhesin. This version contains a 200aa insert that shows similarity (32% identity, 44% similarity over 95 residues) to SP|Q9TL08 a chloroplast enzyme which converts protoporphyrin IX (a hemoglobin precursor) into cholorophyll.; prophage LambdaSa2, PblB complement(1836950..1840624) Streptococcus agalactiae 2603V/R 1014652 NP_688833.1 CDS SAG1843 NC_004116.1 1840625 1841347 R hypothetical protein complement(1840625..1841347) Streptococcus agalactiae 2603V/R 1014653 NP_688834.1 CDS SAG1844 NC_004116.1 1841344 1844079 R hypothetical protein complement(1841344..1844079) Streptococcus agalactiae 2603V/R 1014654 NP_688835.1 CDS SAG1845 NC_004116.1 1844098 1844226 R hypothetical protein complement(1844098..1844226) Streptococcus agalactiae 2603V/R 1014655 NP_688836.1 CDS SAG1846 NC_004116.1 1844265 1844741 R hypothetical protein complement(1844265..1844741) Streptococcus agalactiae 2603V/R 1014656 NP_688837.1 CDS SAG1847 NC_004116.1 1844741 1845424 R hypothetical protein complement(1844741..1845424) Streptococcus agalactiae 2603V/R 1014657 NP_688838.1 CDS SAG1848 NC_004116.1 1845439 1845783 R hypothetical protein complement(1845439..1845783) Streptococcus agalactiae 2603V/R 1014658 NP_688839.1 CDS SAG1849 NC_004116.1 1845770 1846117 R hypothetical protein complement(1845770..1846117) Streptococcus agalactiae 2603V/R 1014659 NP_688840.1 CDS SAG1850 NC_004116.1 1846117 1846422 R hypothetical protein complement(1846117..1846422) Streptococcus agalactiae 2603V/R 1014660 NP_688841.1 CDS SAG1851 NC_004116.1 1846419 1846754 R similar to GB:AE001825; identified by sequence similarity; hypothetical protein complement(1846419..1846754) Streptococcus agalactiae 2603V/R 1014661 NP_688842.1 CDS SAG1852 NC_004116.1 1846775 1848037 R hypothetical protein complement(1846775..1848037) Streptococcus agalactiae 2603V/R 1014662 NP_688843.1 CDS SAG1853 NC_004116.1 1848048 1848590 R similar to OMNI:CC2786; identified by sequence similarity; prophage LambdaSa2, protease complement(1848048..1848590) Streptococcus agalactiae 2603V/R 1014663 NP_688844.1 CDS SAG1854 NC_004116.1 1848640 1849782 R hypothetical protein complement(1848640..1849782) Streptococcus agalactiae 2603V/R 1014664 NP_688845.1 CDS SAG1855 NC_004116.1 1849791 1851503 R identified by match to PFAM protein family HMM PF03354; prophage LambdaSa2, terminase large subunit complement(1849791..1851503) Streptococcus agalactiae 2603V/R 1014665 NP_688846.1 CDS SAG1856 NC_004116.1 1851496 1851981 R hypothetical protein complement(1851496..1851981) Streptococcus agalactiae 2603V/R 1014666 NP_688847.1 CDS SAG1857 NC_004116.1 1852069 1852428 R identified by match to PFAM protein family HMM PF01844; prophage LambdaSa2, HNH endonuclease family protein complement(1852069..1852428) Streptococcus agalactiae 2603V/R 1014667 NP_688848.1 CDS SAG1858 NC_004116.1 1852428 1852715 R hypothetical protein complement(1852428..1852715) Streptococcus agalactiae 2603V/R 1014668 NP_688849.1 CDS SAG1859 NC_004116.1 1853005 1853547 R identified by match to PFAM protein family HMM PF00589; prophage LambdaSa2, site-specific recombinase phage integrase family protein complement(1853005..1853547) Streptococcus agalactiae 2603V/R 1014669 NP_688850.1 CDS SAG1860 NC_004116.1 1853657 1854121 R hypothetical protein complement(1853657..1854121) Streptococcus agalactiae 2603V/R 1014670 NP_688851.1 CDS SAG1861 NC_004116.1 1854118 1854477 R identified by match to PFAM protein family HMM PF01381; prophage LambdaSa2, Cro/CI family transcriptional regulator complement(1854118..1854477) Streptococcus agalactiae 2603V/R 1014671 NP_688852.1 CDS SAG1862 NC_004116.1 1854462 1854722 R hypothetical protein complement(1854462..1854722) Streptococcus agalactiae 2603V/R 1014672 NP_688853.1 CDS ssb-4 NC_004116.1 1854732 1855148 R identified by match to PFAM protein family HMM PF00436; prophage LambdaSa2, single-strand binding protein complement(1854732..1855148) Streptococcus agalactiae 2603V/R 1014673 NP_688854.1 CDS SAG1864 NC_004116.1 1855138 1855344 R hypothetical protein complement(1855138..1855344) Streptococcus agalactiae 2603V/R 1014674 NP_688855.1 CDS SAG1865 NC_004116.1 1855341 1855565 R hypothetical protein complement(1855341..1855565) Streptococcus agalactiae 2603V/R 1014675 NP_688856.1 CDS SAG1866 NC_004116.1 1855697 1856026 R hypothetical protein complement(1855697..1856026) Streptococcus agalactiae 2603V/R 1014676 NP_688857.1 CDS SAG1867 NC_004116.1 1856026 1856517 R hypothetical protein complement(1856026..1856517) Streptococcus agalactiae 2603V/R 1014677 NP_688858.1 CDS SAG1868 NC_004116.1 1856510 1856914 R hypothetical protein complement(1856510..1856914) Streptococcus agalactiae 2603V/R 1014678 NP_688859.1 CDS SAG1869 NC_004116.1 1856911 1858224 R identified by match to PFAM protein family HMM PF00145; Possibly an isoschizomer of Spn5252IP.; prophage LambdaSa2, type II DNA modification methyltransferase complement(1856911..1858224) Streptococcus agalactiae 2603V/R 1014679 NP_688860.1 CDS SAG1870 NC_004116.1 1858224 1859045 R prophage LambdaSa2, DNA replication protein DnaC complement(1858224..1859045) Streptococcus agalactiae 2603V/R 1014680 NP_688861.1 CDS SAG1872 NC_004116.1 1859770 1860372 R hypothetical protein complement(1859770..1860372) Streptococcus agalactiae 2603V/R 1014682 NP_688862.1 CDS dnaC-1 NC_004116.1 1860374 1861705 R identified by match to PFAM protein family HMM PF00772; In low GC Gram-postive bacteria this is known as dnaC. In other prokaryotes, functional equivalent known as dnaB.; prophage LambdaSa2, replicative DNA helicase complement(1860374..1861705) Streptococcus agalactiae 2603V/R 1014683 NP_688863.1 CDS SAG1874 NC_004116.1 1861714 1861977 R hypothetical protein complement(1861714..1861977) Streptococcus agalactiae 2603V/R 1014684 NP_688864.1 CDS SAG1875 NC_004116.1 1861956 1862240 R hypothetical protein complement(1861956..1862240) Streptococcus agalactiae 2603V/R 1014685 NP_688865.1 CDS SAG1876 NC_004116.1 1862240 1862770 R identified by match to PFAM protein family HMM PF01844; prophage LambdaSa2, HNH endonuclease family protein complement(1862240..1862770) Streptococcus agalactiae 2603V/R 1014686 NP_688866.1 CDS SAG1877 NC_004116.1 1862833 1863543 R identified by match to PFAM protein family HMM PF02498; prophage LambdaSa2, antirepressor protein complement(1862833..1863543) Streptococcus agalactiae 2603V/R 1014687 NP_688867.1 CDS SAG1878 NC_004116.1 1863546 1863854 R similar to GP:3676450; identified by sequence similarity; hypothetical protein complement(1863546..1863854) Streptococcus agalactiae 2603V/R 1014688 NP_688868.1 CDS SAG1879 NC_004116.1 1863816 1864286 D hypothetical protein 1863816..1864286 Streptococcus agalactiae 2603V/R 1014689 NP_688869.1 CDS SAG1880 NC_004116.1 1864269 1864433 R hypothetical protein complement(1864269..1864433) Streptococcus agalactiae 2603V/R 1014690 NP_688870.1 CDS SAG1881 NC_004116.1 1864415 1864570 R hypothetical protein complement(1864415..1864570) Streptococcus agalactiae 2603V/R 1014691 NP_688871.1 CDS SAG1882 NC_004116.1 1864719 1865081 D prophage LambdaSa2, repressor protein 1864719..1865081 Streptococcus agalactiae 2603V/R 1014692 NP_688872.1 CDS SAG1883 NC_004116.1 1865082 1865468 D hypothetical protein 1865082..1865468 Streptococcus agalactiae 2603V/R 1014693 NP_688873.1 CDS SAG1884 NC_004116.1 1865521 1865925 D hypothetical protein 1865521..1865925 Streptococcus agalactiae 2603V/R 1014694 NP_688874.1 CDS SAG1885 NC_004116.1 1866047 1867117 D identified by match to PFAM protein family HMM PF00589; prophage LambdaSa2, site-specific recombinase phage integrase family protein 1866047..1867117 Streptococcus agalactiae 2603V/R 1014695 NP_688875.1 CDS SAG1886 NC_004116.1 1867119 1867217 D hypothetical protein 1867119..1867217 Streptococcus agalactiae 2603V/R 1014696 NP_688876.1 CDS SAG1887 NC_004116.1 1867260 1869329 R identified by match to PFAM protein family HMM PF00999; Na+/H+ exchanger family protein complement(1867260..1869329) Streptococcus agalactiae 2603V/R 1014697 NP_688877.1 CDS SAG1888 NC_004116.1 1869331 1869567 R hypothetical protein complement(1869331..1869567) Streptococcus agalactiae 2603V/R 1014698 NP_688878.1 CDS SAG1889 NC_004116.1 1869734 1870687 D identified by match to PFAM protein family HMM PF02016; microcin immunity protein MccF 1869734..1870687 Streptococcus agalactiae 2603V/R 1014699 NP_688879.1 CDS pepO NC_004116.1 1870737 1872632 R identified by match to PFAM protein family HMM PF01431; endopeptidase O complement(1870737..1872632) Streptococcus agalactiae 2603V/R 1014700 NP_688880.1 CDS SAG1891 NC_004116.1 1872780 1873763 D identified by match to PFAM protein family HMM PF01408; Gfo/Idh/MocA family oxidoreductase 1872780..1873763 Streptococcus agalactiae 2603V/R 1014701 NP_688881.1 CDS SAG1892 NC_004116.1 1873809 1874885 R hypothetical protein complement(1873809..1874885) Streptococcus agalactiae 2603V/R 1014702 NP_688882.1 CDS SAG1893 NC_004116.1 1874869 1875048 R hypothetical protein complement(1874869..1875048) Streptococcus agalactiae 2603V/R 1014703 NP_688883.1 CDS SAG1894 NC_004116.1 1875084 1875728 D identified by match to PFAM protein family HMM PF00027; cyclic nucleotide-binding protein 1875084..1875728 Streptococcus agalactiae 2603V/R 1014704 NP_688884.1 CDS def NC_004116.1 1875794 1876408 D cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+); peptide deformylase 1875794..1876408 Streptococcus agalactiae 2603V/R 1014705 NP_688885.1 CDS regR NC_004116.1 1876479 1877480 R identified by match to PFAM protein family HMM PF00532; RegR family transcriptional regulator complement(1876479..1877480) Streptococcus agalactiae 2603V/R 1014706 NP_688886.1 CDS SAG1897 NC_004116.1 1877560 1879464 R hypothetical protein complement(1877560..1879464) Streptococcus agalactiae 2603V/R 1014707 NP_688887.1 CDS SAG1898 NC_004116.1 1879544 1880359 R PTS system transporter subunit IID complement(1879544..1880359) Streptococcus agalactiae 2603V/R 1014708 NP_688888.1 CDS SAG1899 NC_004116.1 1880346 1881212 R PTS system transporter subunit IIC complement(1880346..1881212) Streptococcus agalactiae 2603V/R 1014709 NP_688889.1 CDS SAG1900 NC_004116.1 1881248 1881742 R PTS system transporter subunit IIB complement(1881248..1881742) Streptococcus agalactiae 2603V/R 1014710 NP_688890.1 CDS SAG1901 NC_004116.1 1881797 1882993 R similar to GP:5869507; identified by sequence similarity; glucuronyl hydrolase complement(1881797..1882993) Streptococcus agalactiae 2603V/R 1014711 NP_688891.1 CDS SAG1902 NC_004116.1 1882996 1883430 R PTS system transporter subunit IIA complement(1882996..1883430) Streptococcus agalactiae 2603V/R 1014712 NP_688892.1 CDS SAG1903 NC_004116.1 1883531 1883635 D hypothetical protein 1883531..1883635 Streptococcus agalactiae 2603V/R 1014713 NP_688893.1 CDS SAG1904 NC_004116.1 1883708 1884520 D Involved in the nonphosphorylative, ketogenic oxidation of glucose and oxidizes gluconate to 5-ketogluconate; gluconate 5-dehydrogenase 1883708..1884520 Streptococcus agalactiae 2603V/R 1014714 NP_688894.1 CDS SAG1905 NC_004116.1 1884537 1885175 D hypothetical protein 1884537..1885175 Streptococcus agalactiae 2603V/R 1014715 NP_688895.1 CDS SAG1906 NC_004116.1 1885201 1886208 D identified by match to PFAM protein family HMM PF00294; carbohydrate kinase 1885201..1886208 Streptococcus agalactiae 2603V/R 1014716 NP_688896.1 CDS eda-2 NC_004116.1 1886220 1886858 D catalyzes the formation of pyruvate and glyoxylate from 4-hydroxy-2-oxoglutarate; or pyruvate and D-glyceraldehyde 3-phosphate from 2-dehydro-3-deoxy-D-glyconate 6-phosphate; keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase 1886220..1886858 Streptococcus agalactiae 2603V/R 1014717 NP_688897.1 CDS SAG1908 NC_004116.1 1887919 1889418 D hypothetical protein 1887919..1889418 Streptococcus agalactiae 2603V/R 1014718 NP_688898.1 CDS SAG1909 NC_004116.1 1889589 1890203 R identified by match to PFAM protein family HMM PF00881; nitroreductase family protein complement(1889589..1890203) Streptococcus agalactiae 2603V/R 1014719 NP_688899.1 CDS SAG1910 NC_004116.1 1890336 1890761 R identified by match to PFAM protein family HMM PF01047; MarR family transcriptional regulator complement(1890336..1890761) Streptococcus agalactiae 2603V/R 1014720 NP_688900.1 CDS polC NC_004116.1 1890888 1895294 R catalyzes DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time; required for leading strand synthesis; PolC exhibits 3' to 5' exonuclease activity; DNA polymerase III PolC complement(1890888..1895294) Streptococcus agalactiae 2603V/R 1014721 NP_688901.1 CDS SAG1912 NC_004116.1 1895417 1896001 R identified by match to PFAM protein family HMM PF01832; N-acetylmuramoyl-L-alanine amidase complement(1895417..1896001) Streptococcus agalactiae 2603V/R 1014722 NP_688902.1 CDS proS NC_004116.1 1896126 1897979 R catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro); prolyl-tRNA synthetase complement(1896126..1897979) Streptococcus agalactiae 2603V/R 1014723 NP_688903.1 CDS SAG1914 NC_004116.1 1898071 1899330 R identified by match to TIGR protein family HMM TIGR00054; zinc metalloprotease complement(1898071..1899330) Streptococcus agalactiae 2603V/R 1014724 NP_688904.1 CDS cdsA NC_004116.1 1899361 1900155 R identified by match to PFAM protein family HMM PF01148; phosphatidate cytidylyltransferase complement(1899361..1900155) Streptococcus agalactiae 2603V/R 1014725 NP_688905.1 CDS uppS NC_004116.1 1900170 1900922 R catalyzes the formation of undecaprenyl pyrophosphate from isopentenyl pyrophosphate; undecaprenyl pyrophosphate synthase complement(1900170..1900922) Streptococcus agalactiae 2603V/R 1014726 NP_688906.1 CDS yajC NC_004116.1 1901089 1901430 R member of preprotein translocase; forms a heterotrimer with SecD and SecF; links the SecD/SecF/YajC/YidC complex with the SecY/SecE/SecG complex; preprotein translocase subunit YajC complement(1901089..1901430) Streptococcus agalactiae 2603V/R 1014727 NP_688907.1 CDS SAG1918 NC_004116.1 1901507 1901851 R The product of this gene was detected by Western blot analysis. For details on the method see Tettelin et al. 2002.; hypothetical protein complement(1901507..1901851) Streptococcus agalactiae 2603V/R 1014728 NP_688908.1 CDS SAG1919 NC_004116.1 1902042 1903205 R identified by match to PFAM protein family HMM PF00390; malate oxidoreductase complement(1902042..1903205) Streptococcus agalactiae 2603V/R 1014729 NP_688909.1 CDS SAG1920 NC_004116.1 1903230 1904567 R identified by match to PFAM protein family HMM PF03390; CCS family citrate carrier protein complement(1903230..1904567) Streptococcus agalactiae 2603V/R 1014730 NP_688910.1 CDS SAG1921 NC_004116.1 1904721 1906247 D similar to OMNI:NTL01SPL0863; identified by sequence similarity; sensor histidine kinase 1904721..1906247 Streptococcus agalactiae 2603V/R 1014731 NP_688911.1 CDS SAG1922 NC_004116.1 1906249 1906938 D identified by match to PFAM protein family HMM PF00072; response regulator 1906249..1906938 Streptococcus agalactiae 2603V/R 1014732 NP_688912.1 CDS galE NC_004116.1 1906951 1907946 R identified by match to PFAM protein family HMM PF01370; UDP-glucose 4-epimerase complement(1906951..1907946) Streptococcus agalactiae 2603V/R 1014733 NP_688913.1 CDS dexB NC_004116.1 1908034 1909641 R identified by match to PFAM protein family HMM PF00128; glucan 1,6-alpha-glucosidase complement(1908034..1909641) Streptococcus agalactiae 2603V/R 1014734 NP_688914.1 CDS SAG1925 NC_004116.1 1909769 1910902 R identified by match to PFAM protein family HMM PF00005; sugar ABC transporter ATP-binding protein complement(1909769..1910902) Streptococcus agalactiae 2603V/R 1014735 NP_688915.1 CDS SAG1926 NC_004116.1 1911003 1911854 R identified by match to TIGR protein family HMM TIGR01199; helix-turn-helix domain-containing protein complement(1911003..1911854) Streptococcus agalactiae 2603V/R 1014736 NP_688916.1 CDS SAG1927 NC_004116.1 1911949 1912845 R identified by match to PFAM protein family HMM PF02693; aldolase 1 epimerase LacX complement(1911949..1912845) Streptococcus agalactiae 2603V/R 1014737 NP_688917.1 CDS lacD NC_004116.1 1912899 1913876 R catalyzes the reversible reaction of dihydroxyacetone phosphate with glyceraldehyde 3-phosphate to produce tagatose 1,6-bisphosphate; in Streptococcus pyogenes there are two paralogs of tagatose-bisphosphate aldolase, encoded by lacD1 and lacD2; expression of lacD1 is highly regulated by environmental conditions while lacD2 specializes in an efficient utilization of carbohydrate sources; tagatose 1,6-diphosphate aldolase complement(1912899..1913876) Streptococcus agalactiae 2603V/R 1014738 NP_688918.1 CDS lacC NC_004116.1 1913878 1914810 R catalyzes the formation of tagatose 1,6-bisphosphate from tagatose 6-phosphate and ATP; tagatose-6-phosphate kinase complement(1913878..1914810) Streptococcus agalactiae 2603V/R 1014739 NP_688919.1 CDS lacB NC_004116.1 1914821 1915336 R catalyzes the interconversion of galactose 6-phosphate to tagatose 6-phosphate; galactose-6-phosphate isomerase subunit LacB complement(1914821..1915336) Streptococcus agalactiae 2603V/R 1014740 NP_688920.1 CDS lacA NC_004116.1 1915357 1915782 R catalyzes the interconversion of galactose 6-phosphate to tagatose 6-phosphate; tagatose pathway for galactose utilization; galactose-6-phosphate isomerase subunit LacA complement(1915357..1915782) Streptococcus agalactiae 2603V/R 1014741 NP_688921.1 CDS SAG1932 NC_004116.1 1916030 1918480 R identified by match to PFAM protein family HMM PF02012; neuraminidase-like protein complement(1916030..1918480) Streptococcus agalactiae 2603V/R 1014742 NP_688922.1 CDS SAG1933 NC_004116.1 1918719 1920167 R PTS system transporter subunit IIC complement(1918719..1920167) Streptococcus agalactiae 2603V/R 1014743 NP_688923.1 CDS SAG1934 NC_004116.1 1920207 1920512 R similar to OMNI:NTL01SPL1345; identified by sequence similarity; PTS system transporter subunit IIB complement(1920207..1920512) Streptococcus agalactiae 2603V/R 1014744 NP_688924.1 CDS SAG1935 NC_004116.1 1920514 1920987 R PTS system transporter subunit IIA complement(1920514..1920987) Streptococcus agalactiae 2603V/R 1014745 NP_688925.1 CDS lacR-2 NC_004116.1 1921197 1921973 D identified by match to PFAM protein family HMM PF00455; lactose phosphotransferase system repressor 1921197..1921973 Streptococcus agalactiae 2603V/R 1014746 NP_688926.1 CDS SAG1938 NC_004116.1 1924811 1925734 R identified by match to PFAM protein family HMM PF01297; The product of this gene was detected by Western blot analysis. For details on the method see Tettelin et al. 2002.; adhesion lipoprotein complement(1924811..1925734) Streptococcus agalactiae 2603V/R 1014748 NP_688927.1 CDS SAG1939 NC_004116.1 1925989 1926432 R hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr); possible defense mechanism against a harmful effect of D-tyrosine; D-tyrosyl-tRNA(Tyr) deacylase complement(1925989..1926432) Streptococcus agalactiae 2603V/R 1014749 NP_688928.1 CDS SAG1940 NC_004116.1 1926442 1928658 R identified by match to PFAM protein family HMM PF01842; GTP pyrophosphokinase complement(1926442..1928658) Streptococcus agalactiae 2603V/R 1014750 NP_688929.1 CDS cpdB NC_004116.1 1928918 1931320 D in Escherichia coli this is a periplasmic enzyme while in gram positive organisms it may be anchored at the cell surface; functions during ribonucleic acid degradation; 2',3'-cyclic nucleotides are first converted to 3'-nucleotide and then cleaved to yield a ribonucleotide and a phosphate; bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase/3'-nucleotidase precursor protein 1928918..1931320 Streptococcus agalactiae 2603V/R 1014751 NP_688930.1 CDS nrdI-2 NC_004116.1 1931477 1931932 D has a stimulatory effect on the ribonucleotide reductase activity of NrdH with NrdEF; flavoprotein NrdI 1931477..1931932 Streptococcus agalactiae 2603V/R 1014752 NP_688931.1 CDS SAG1943 NC_004116.1 1931943 1932980 D hypothetical protein 1931943..1932980 Streptococcus agalactiae 2603V/R 1014753 NP_688932.1 CDS SAG1944 NC_004116.1 1932980 1933477 D hypothetical protein 1932980..1933477 Streptococcus agalactiae 2603V/R 1014754 NP_688933.1 CDS SAG1945 NC_004116.1 1933699 1934736 R identified by match to PFAM protein family HMM PF01547; iron ABC transporter substrate-binding protein complement(1933699..1934736) Streptococcus agalactiae 2603V/R 1014755 NP_688934.1 CDS SAG1946 NC_004116.1 1934748 1935521 R identified by match to PFAM protein family HMM PF00072; DNA-binding response regulator complement(1934748..1935521) Streptococcus agalactiae 2603V/R 1014756 NP_688935.1 CDS SAG1947 NC_004116.1 1935525 1937174 R hypothetical protein complement(1935525..1937174) Streptococcus agalactiae 2603V/R 1014757 NP_688936.1 CDS SAG1948 NC_004116.1 1937312 1938139 R PTS system transporter subunit IID complement(1937312..1938139) Streptococcus agalactiae 2603V/R 1014758 NP_688937.1 CDS SAG1949 NC_004116.1 1938136 1938945 R PTS system transporter subunit IIC complement(1938136..1938945) Streptococcus agalactiae 2603V/R 1014759 NP_688938.1 CDS SAG1950 NC_004116.1 1938961 1939452 R PTS system transporter subunit IIB complement(1938961..1939452) Streptococcus agalactiae 2603V/R 1014760 NP_688939.1 CDS SAG1951 NC_004116.1 1939470 1939895 R PTS system transporter subunit IIA complement(1939470..1939895) Streptococcus agalactiae 2603V/R 1014761 NP_688940.1 CDS SAG1952 NC_004116.1 1940142 1941203 R similar to GP:7960293; identified by sequence similarity; hypothetical protein complement(1940142..1941203) Streptococcus agalactiae 2603V/R 1014762 NP_688941.1 CDS SAG1953 NC_004116.1 1941228 1941410 D hypothetical protein 1941228..1941410 Streptococcus agalactiae 2603V/R 1014763 NP_688942.1 CDS SAG1954 NC_004116.1 1941405 1942559 R hypothetical protein complement(1941405..1942559) Streptococcus agalactiae 2603V/R 1014764 NP_688943.1 CDS SAG1955 NC_004116.1 1942565 1943413 R identified by match to PFAM protein family HMM PF00005; ABC transporter ATP-binding protein complement(1942565..1943413) Streptococcus agalactiae 2603V/R 1014765 NP_688944.1 CDS SAG1957 NC_004116.1 1943904 1944656 R identified by match to PFAM protein family HMM PF00072; response regulator complement(1943904..1944656) Streptococcus agalactiae 2603V/R 1014767 NP_688945.1 CDS SAG1958 NC_004116.1 1944933 1945763 R hypothetical protein complement(1944933..1945763) Streptococcus agalactiae 2603V/R 1014768 NP_688946.1 CDS SAG1959 NC_004116.1 1945802 1947985 R identified by match to PFAM protein family HMM PF00358; PTS system transporter subunit IIABC complement(1945802..1947985) Streptococcus agalactiae 2603V/R 1014769 NP_688947.1 CDS SAG1960 NC_004116.1 1948143 1949798 R identified by match to PFAM protein family HMM PF00512; sensor histidine kinase complement(1948143..1949798) Streptococcus agalactiae 2603V/R 1014770 NP_688948.1 CDS phoB NC_004116.1 1949791 1950468 R identified by match to PFAM protein family HMM PF00072; phosphate regulon response regulator PhoB complement(1949791..1950468) Streptococcus agalactiae 2603V/R 1014771 NP_688949.1 CDS SAG1962 NC_004116.1 1950468 1951124 R identified by match to PFAM protein family HMM PF01895; phosphate transport system regulatory protein PhoU complement(1950468..1951124) Streptococcus agalactiae 2603V/R 1014772 NP_688950.1 CDS SAG1963 NC_004116.1 1951121 1951882 R ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation; phosphate transporter ATP-binding protein complement(1951121..1951882) Streptococcus agalactiae 2603V/R 1014773 NP_688951.1 CDS SAG1964 NC_004116.1 1951863 1952741 R identified by match to PFAM protein family HMM PF00528; phosphate ABC transporter permease complement(1951863..1952741) Streptococcus agalactiae 2603V/R 1014774 NP_688952.1 CDS SAG1965 NC_004116.1 1952743 1953588 R identified by match to PFAM protein family HMM PF00528; phosphate ABC transporter permease complement(1952743..1953588) Streptococcus agalactiae 2603V/R 1014775 NP_688953.1 CDS SAG1966 NC_004116.1 1953603 1954484 R hemolysin complement(1953603..1954484) Streptococcus agalactiae 2603V/R 1014776 NP_688954.1 CDS SAG1967 NC_004116.1 1954685 1955272 R hypothetical protein complement(1954685..1955272) Streptococcus agalactiae 2603V/R 1014777 NP_688955.1 CDS SAG1968 NC_004116.1 1955269 1956009 R in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA; cells lacking this function can grow, but are outcompeted by wild-type; SAM-dependent m(3)U1498 methyltransferase; 16S ribosomal RNA methyltransferase RsmE complement(1955269..1956009) Streptococcus agalactiae 2603V/R 1014778 NP_688956.1 CDS prmA NC_004116.1 1956009 1956962 R methylates ribosomal protein L11 at multiple amino acid positions; mutations of these genes in Escherichia coli or Thermus thermophilus has no apparent phenotype; 50S ribosomal protein L11 methyltransferase complement(1956009..1956962) Streptococcus agalactiae 2603V/R 1014779 NP_688957.1 CDS SAG1970 NC_004116.1 1956959 1957267 R hypothetical protein complement(1956959..1957267) Streptococcus agalactiae 2603V/R 1014780 NP_688958.1 CDS SAG1971 NC_004116.1 1957329 1957454 D hypothetical protein 1957329..1957454 Streptococcus agalactiae 2603V/R 1014781 NP_688959.1 CDS SAG1972 NC_004116.1 1957541 1958257 D identified by match to PFAM protein family HMM PF00376; MerR family transcriptional regulator 1957541..1958257 Streptococcus agalactiae 2603V/R 1014782 NP_688960.1 CDS SAG1973 NC_004116.1 1958296 1958766 R identified by match to PFAM protein family HMM PF00583; acetyltransferase complement(1958296..1958766) Streptococcus agalactiae 2603V/R 1014783 NP_688961.1 CDS SAG1974 NC_004116.1 1958738 1959196 R identified by match to PFAM protein family HMM PF00293; MutT/nudix family protein complement(1958738..1959196) Streptococcus agalactiae 2603V/R 1014784 NP_688962.1 CDS SAG1975 NC_004116.1 1959183 1959326 R hypothetical protein complement(1959183..1959326) Streptococcus agalactiae 2603V/R 1014785 NP_688963.1 CDS SAG1976 NC_004116.1 1959332 1959802 R hypothetical protein complement(1959332..1959802) Streptococcus agalactiae 2603V/R 1014786 NP_688964.1 CDS SAG1977 NC_004116.1 1960129 1960620 D identified by match to PFAM protein family HMM PF00583; acetyltransferase 1960129..1960620 Streptococcus agalactiae 2603V/R 1014787 NP_688965.1 CDS SAG1978 NC_004116.1 1960613 1961881 D identified by match to PFAM protein family HMM PF00004; recombination factor protein RarA 1960613..1961881 Streptococcus agalactiae 2603V/R 1014788 NP_688966.1 CDS SAG1979 NC_004116.1 1962397 1963158 R hypothetical protein complement(1962397..1963158) Streptococcus agalactiae 2603V/R 1014790 NP_688967.1 CDS SAG1980 NC_004116.1 1963155 1964057 R identified by match to PFAM protein family HMM PF00005; ABC transporter ATP-binding protein complement(1963155..1964057) Streptococcus agalactiae 2603V/R 1014791 NP_688968.1 CDS SAG1981 NC_004116.1 1964054 1964260 R hypothetical protein complement(1964054..1964260) Streptococcus agalactiae 2603V/R 1014792 NP_688969.1 CDS SAG1982 NC_004116.1 1964250 1965329 R identified by match to PFAM protein family HMM PF01381; Cro/CI family transcriptional regulator complement(1964250..1965329) Streptococcus agalactiae 2603V/R 1014793 NP_688970.1 CDS SAG1983 NC_004116.1 1965710 1966027 D hypothetical protein 1965710..1966027 Streptococcus agalactiae 2603V/R 1014794 NP_688971.1 CDS SAG1984 NC_004116.1 1966024 1966590 D hypothetical protein 1966024..1966590 Streptococcus agalactiae 2603V/R 1014795 NP_688972.1 CDS SAG1985 NC_004116.1 1966644 1966799 R hypothetical protein complement(1966644..1966799) Streptococcus agalactiae 2603V/R 1014796 NP_688973.1 CDS SAG1986 NC_004116.1 1966825 1967952 R identified by match to PFAM protein family HMM PF00589; phage integrase family site specific recombinase complement(1966825..1967952) Streptococcus agalactiae 2603V/R 1014797 NP_688974.1 CDS SAG1987 NC_004116.1 1967956 1968141 R hypothetical protein complement(1967956..1968141) Streptococcus agalactiae 2603V/R 1014798 NP_688975.1 CDS SAG1988 NC_004116.1 1968202 1969230 R hypothetical protein complement(1968202..1969230) Streptococcus agalactiae 2603V/R 1014799 NP_688976.1 CDS SAG1989 NC_004116.1 1969233 1969652 R hypothetical protein complement(1969233..1969652) Streptococcus agalactiae 2603V/R 1014800 NP_688977.1 CDS SAG1990 NC_004116.1 1969978 1970361 R hypothetical protein complement(1969978..1970361) Streptococcus agalactiae 2603V/R 1014801 NP_688978.1 CDS SAG1991 NC_004116.1 1970585 1971199 D identified by match to PFAM protein family HMM PF01381; Cro/CI family transcriptional regulator 1970585..1971199 Streptococcus agalactiae 2603V/R 1014802 NP_688979.1 CDS SAG1992 NC_004116.1 1971372 1972928 R similar to PID:928833; identified by sequence similarity; The product of this gene was detected by Western blot analysis. For details on the method see Tettelin et al. 2002.; hypothetical protein complement(1971372..1972928) Streptococcus agalactiae 2603V/R 1014803 NP_688980.1 CDS SAG1993 NC_004116.1 1973269 1974390 R identified by match to PFAM protein family HMM PF00589; phage integrase family site specific recombinase complement(1973269..1974390) Streptococcus agalactiae 2603V/R 1014804 NP_688981.1 CDS SAG1994 NC_004116.1 1974440 1974766 R hypothetical protein complement(1974440..1974766) Streptococcus agalactiae 2603V/R 1014805 NP_688982.1 CDS SAG1995 NC_004116.1 1974959 1975591 R hypothetical protein complement(1974959..1975591) Streptococcus agalactiae 2603V/R 1014806 NP_688983.1 CDS SAG1996 NC_004116.1 1975672 1976463 R cell wall surface anchor family protein complement(1975672..1976463) Streptococcus agalactiae 2603V/R 1014807 NP_688984.1 CDS SAG1997 NC_004116.1 1976480 1977028 R hypothetical protein complement(1976480..1977028) Streptococcus agalactiae 2603V/R 1014808 NP_688985.1 CDS SAG1998 NC_004116.1 1977028 1978401 R hypothetical protein complement(1977028..1978401) Streptococcus agalactiae 2603V/R 1014809 NP_688986.1 CDS SAG1999 NC_004116.1 1978564 1978707 D hypothetical protein 1978564..1978707 Streptococcus agalactiae 2603V/R 1014810 NP_688987.1 CDS SAG2000 NC_004116.1 1978897 1980897 R similar to GP:6782407; identified by sequence similarity; hypothetical protein complement(1978897..1980897) Streptococcus agalactiae 2603V/R 1014811 NP_688988.1 CDS SAG2001 NC_004116.1 1980913 1983183 R This gene is interrupted by an IS1381 element.; conjugal transfer protein, interruption-C complement(1980913..1983183) Streptococcus agalactiae 2603V/R 1014812 NP_688989.1 CDS SAG2002 NC_004116.1 1983230 1983619 R identified by match to PFAM protein family HMM PF01609; IS1381 transposase protein B complement(1983230..1983619) Streptococcus agalactiae 2603V/R 1014813 NP_688990.2 CDS SAG2003 NC_004116.1 1983652 1984275 R similar to OMNI:SP0537; identified by sequence similarity; IS1381 transposase protein A complement(1983652..1984275) Streptococcus agalactiae 2603V/R 1014814 NP_688991.1 CDS SAG2005 NC_004116.1 1984296 1984706 R hypothetical protein complement(1984296..1984706) Streptococcus agalactiae 2603V/R 1014816 NP_688992.1 CDS SAG2006 NC_004116.1 1984717 1984983 R hypothetical protein complement(1984717..1984983) Streptococcus agalactiae 2603V/R 1014817 NP_688993.1 CDS SAG2007 NC_004116.1 1985004 1985957 R hypothetical protein complement(1985004..1985957) Streptococcus agalactiae 2603V/R 1014818 NP_688994.1 CDS SAG2008 NC_004116.1 1986010 1986264 R hypothetical protein complement(1986010..1986264) Streptococcus agalactiae 2603V/R 1014819 NP_688995.1 CDS SAG2009 NC_004116.1 1986257 1986523 R hypothetical protein complement(1986257..1986523) Streptococcus agalactiae 2603V/R 1014820 NP_688996.1 CDS SAG2010 NC_004116.1 1986668 1987141 R hypothetical protein complement(1986668..1987141) Streptococcus agalactiae 2603V/R 1014821 NP_688997.1 CDS SAG2011 NC_004116.1 1987149 1987631 R hypothetical protein complement(1987149..1987631) Streptococcus agalactiae 2603V/R 1014822 NP_688998.1 CDS SAG2012 NC_004116.1 1987684 1987956 R hypothetical protein complement(1987684..1987956) Streptococcus agalactiae 2603V/R 1014823 NP_688999.1 CDS SAG2013 NC_004116.1 1988091 1988660 R hypothetical protein complement(1988091..1988660) Streptococcus agalactiae 2603V/R 1014824 NP_689000.1 CDS SAG2014 NC_004116.1 1988663 1990012 R hypothetical protein complement(1988663..1990012) Streptococcus agalactiae 2603V/R 1014825 NP_689001.1 CDS SAG2015 NC_004116.1 1990209 1990508 R identified by match to PFAM protein family HMM PF01381; Cro/CI family transcriptional regulator complement(1990209..1990508) Streptococcus agalactiae 2603V/R 1014826 NP_689002.1 CDS SAG2016 NC_004116.1 1990492 1990869 R hypothetical protein complement(1990492..1990869) Streptococcus agalactiae 2603V/R 1014827 NP_689003.1 CDS SAG2017 NC_004116.1 1990885 1992174 R identified by match to PFAM protein family HMM PF01381; Cro/CI family transcriptional regulator complement(1990885..1992174) Streptococcus agalactiae 2603V/R 1014828 NP_689004.1 CDS SAG2018 NC_004116.1 1992405 1994066 R identified by match to PFAM protein family HMM PF01580; DNA translocase FtsK complement(1992405..1994066) Streptococcus agalactiae 2603V/R 1014829 NP_689005.1 CDS SAG2019 NC_004116.1 1994143 1994604 R hypothetical protein complement(1994143..1994604) Streptococcus agalactiae 2603V/R 1014830 NP_689006.1 CDS SAG2020 NC_004116.1 1994626 1994922 R hypothetical protein complement(1994626..1994922) Streptococcus agalactiae 2603V/R 1014831 NP_689007.1 CDS SAG2021 NC_004116.1 1994982 1997462 R identified by match to PFAM protein family HMM PF00746; cell wall surface anchor family protein complement(1994982..1997462) Streptococcus agalactiae 2603V/R 1014832 NP_689008.1 CDS SAG2022 NC_004116.1 1997467 1998720 R identified by match to PFAM protein family HMM PF01610; This gene is located in a transposable element that also encodes two genes for a mercuric resistance operon, and there are two copies of the transposable element in this strain.; ISL3 family transposase complement(1997467..1998720) Streptococcus agalactiae 2603V/R 1014833 NP_689009.1 CDS merA-2 NC_004116.1 1998880 2000520 R identified by match to PFAM protein family HMM PF00070; mercuric reductase complement(1998880..2000520) Streptococcus agalactiae 2603V/R 1014834 NP_689010.1 CDS merR-2 NC_004116.1 2000549 2000941 R identified by match to PFAM protein family HMM PF00376; mercuric resistance operon regulatory protein MerR complement(2000549..2000941) Streptococcus agalactiae 2603V/R 1014835 NP_689011.1 CDS SAG2025 NC_004116.1 2001647 2003215 D identified by match to PFAM protein family HMM PF01566; Mn2+/Fe2+ transporter 2001647..2003215 Streptococcus agalactiae 2603V/R 1014836 NP_689012.1 CDS SAG2026 NC_004116.1 2003783 2004505 R similar to OMNI:NTL01SA2412; identified by sequence similarity; hypothetical protein complement(2003783..2004505) Streptococcus agalactiae 2603V/R 1014837 NP_689013.1 CDS SAG2027 NC_004116.1 2004509 2005126 R identified by match to PFAM protein family HMM PF00005; ABC transporter ATP-binding protein complement(2004509..2005126) Streptococcus agalactiae 2603V/R 1014838 NP_689014.1 CDS SAG2028 NC_004116.1 2005184 2005294 R hypothetical protein complement(2005184..2005294) Streptococcus agalactiae 2603V/R 1014839 NP_689015.1 CDS SAG2029 NC_004116.1 2005813 2006667 R similar to SP:P12055 GB:X06627 PID:46644; identified by sequence similarity; streptomycin resistance protein complement(2005813..2006667) Streptococcus agalactiae 2603V/R 1014840 NP_689016.1 CDS SAG2030 NC_004116.1 2006846 2007238 R hypothetical protein complement(2006846..2007238) Streptococcus agalactiae 2603V/R 1014841 NP_689017.1 CDS SAG2031 NC_004116.1 2007673 2008281 R hypothetical protein complement(2007673..2008281) Streptococcus agalactiae 2603V/R 1014842 NP_689018.1 CDS SAG2032 NC_004116.1 2008268 2008603 R hypothetical protein complement(2008268..2008603) Streptococcus agalactiae 2603V/R 1014843 NP_689019.1 CDS SAG2033 NC_004116.1 2009125 2009613 R identified by match to PFAM protein family HMM PF00583; acetyltransferase complement(2009125..2009613) Streptococcus agalactiae 2603V/R 1014844 NP_689020.1 CDS SAG2034 NC_004116.1 2009782 2010525 R similar to OMNI:NTL01BH0292; identified by sequence similarity; hypothetical protein complement(2009782..2010525) Streptococcus agalactiae 2603V/R 1014845 NP_689021.1 CDS SAG2035 NC_004116.1 2010540 2011442 R identified by match to PFAM protein family HMM PF00005; ABC transporter ATP-binding protein complement(2010540..2011442) Streptococcus agalactiae 2603V/R 1014846 NP_689022.1 CDS SAG2036 NC_004116.1 2011439 2011645 R hypothetical protein complement(2011439..2011645) Streptococcus agalactiae 2603V/R 1014847 NP_689023.1 CDS SAG2037 NC_004116.1 2011647 2012723 R identified by match to PFAM protein family HMM PF01381; Cro/CI family transcriptional regulator complement(2011647..2012723) Streptococcus agalactiae 2603V/R 1014848 NP_689024.1 CDS SAG2038 NC_004116.1 2012972 2013586 R identified by match to PFAM protein family HMM PF01569; PAP2 family protein complement(2012972..2013586) Streptococcus agalactiae 2603V/R 1014849 NP_689025.1 CDS SAG2039 NC_004116.1 2013800 2014096 D hypothetical protein 2013800..2014096 Streptococcus agalactiae 2603V/R 1014850 NP_689026.1 CDS SAG2040 NC_004116.1 2014113 2014673 D hypothetical protein 2014113..2014673 Streptococcus agalactiae 2603V/R 1014851 NP_689027.1 CDS SAG2041 NC_004116.1 2014978 2015841 D identified by match to PFAM protein family HMM PF02517; protease 2014978..2015841 Streptococcus agalactiae 2603V/R 1014852 NP_689028.1 CDS SAG2042 NC_004116.1 2015998 2016300 R identified by match to PFAM protein family HMM PF00581; rhodanese-like domain-containing protein complement(2015998..2016300) Streptococcus agalactiae 2603V/R 1014853 NP_689029.1 CDS cfb NC_004116.1 2016473 2017240 R similar to SP:P09879; identified by sequence similarity; cAMP factor complement(2016473..2017240) Streptococcus agalactiae 2603V/R 1014854 NP_689030.1 CDS SAG2044 NC_004116.1 2017460 2017648 R hypothetical protein complement(2017460..2017648) Streptococcus agalactiae 2603V/R 1014855 NP_689031.1 CDS SAG2045 NC_004116.1 2018009 2018548 D topology modulation protein 2018009..2018548 Streptococcus agalactiae 2603V/R 1014856 NP_689032.1 CDS SAG2046 NC_004116.1 2018749 2019834 D identified by match to PFAM protein family HMM PF00465; glycerol dehydrogenase 2018749..2019834 Streptococcus agalactiae 2603V/R 1014857 NP_689033.1 CDS SAG2047 NC_004116.1 2019999 2020706 R hypothetical protein complement(2019999..2020706) Streptococcus agalactiae 2603V/R 1014858 NP_689034.1 CDS SAG2048 NC_004116.1 2021053 2022897 R catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine; expressed in B. subtilis under methionine starvation conditions; bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase complement(2021053..2022897) Streptococcus agalactiae 2603V/R 1014859 NP_689035.1 CDS metE NC_004116.1 2022942 2025179 R catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine to form methionine; 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase complement(2022942..2025179) Streptococcus agalactiae 2603V/R 1014860 NP_689036.1 CDS SAG2050 NC_004116.1 2025549 2025872 R hypothetical protein complement(2025549..2025872) Streptococcus agalactiae 2603V/R 1014861 NP_689037.1 CDS SAG2051 NC_004116.1 2025862 2026554 R branched-chain amino acid transport protein AzlC complement(2025862..2026554) Streptococcus agalactiae 2603V/R 1014862 NP_689038.1 CDS SAG2052 NC_004116.1 2026789 2026914 D hypothetical protein 2026789..2026914 Streptococcus agalactiae 2603V/R 1014863 NP_689039.1 CDS SAG2053 NC_004116.1 2026877 2031589 D identified by match to PFAM protein family HMM PF00082; serine protease 2026877..2031589 Streptococcus agalactiae 2603V/R 1014864 NP_689040.1 CDS SAG2054 NC_004116.1 2031822 2032508 D identified by match to PFAM protein family HMM PF00072; DNA-binding response regulator 2031822..2032508 Streptococcus agalactiae 2603V/R 1014865 NP_689041.1 CDS SAG2055 NC_004116.1 2032505 2033893 D identified by match to PFAM protein family HMM PF00512; sensor histidine kinase 2032505..2033893 Streptococcus agalactiae 2603V/R 1014866 NP_689042.1 CDS SAG2056 NC_004116.1 2033986 2034594 D similar to OMNI:EF0852; identified by sequence similarity; hypothetical protein 2033986..2034594 Streptococcus agalactiae 2603V/R 1014867 NP_689043.1 CDS leuS NC_004116.1 2034681 2037182 R leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase; leucyl-tRNA synthetase complement(2034681..2037182) Streptococcus agalactiae 2603V/R 1014868 NP_689044.1 CDS SAG2058 NC_004116.1 2037559 2038806 D identified by match to PFAM protein family HMM PF00083; major facilitator family protein 2037559..2038806 Streptococcus agalactiae 2603V/R 1014869 NP_689045.1 CDS SAG2059 NC_004116.1 2038849 2039694 R identified by match to PFAM protein family HMM PF01734; The product of this gene was detected by Western blot analysis. For details on the method see Tettelin et al. 2002.; hypothetical protein complement(2038849..2039694) Streptococcus agalactiae 2603V/R 1014870 NP_689046.1 CDS SAG2060 NC_004116.1 2039899 2041095 D identified by match to PFAM protein family HMM PF01501; glycosyl transferase family protein 2039899..2041095 Streptococcus agalactiae 2603V/R 1014871 NP_689047.1 CDS SAG2061 NC_004116.1 2041160 2042365 D identified by match to PFAM protein family HMM PF01501; glycosyl transferase family protein 2041160..2042365 Streptococcus agalactiae 2603V/R 1014872 NP_689048.1 CDS nusG NC_004116.1 2042412 2042951 R Modulates Rho-dependent transcription termination; transcription antitermination protein NusG complement(2042412..2042951) Streptococcus agalactiae 2603V/R 1014873 NP_689049.1 CDS SAG2063 NC_004116.1 2043157 2045049 R identified by match to PFAM protein family HMM PF00746; pathogenicity protein complement(2043157..2045049) Streptococcus agalactiae 2603V/R 1014874 NP_689050.1 CDS secE NC_004116.1 2045361 2045534 R forms a complex with SecY and SecG; SecYEG forms a protein-conducting channel to which secA binds and translocates targeted polypeptides across the cytoplasmic membrane, a process driven by ATP and a proton-motive force; preprotein translocase subunit SecE complement(2045361..2045534) Streptococcus agalactiae 2603V/R 1014875 NP_689051.1 CDS rpmG NC_004116.1 2045570 2045722 R in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group have the CXXC motif; 50S ribosomal protein L33 complement(2045570..2045722) Streptococcus agalactiae 2603V/R 1014876 NP_689052.1 CDS pbp2A NC_004116.1 2045771 2048092 R identified by match to PFAM protein family HMM PF00905; penicillin-binding protein 2A complement(2045771..2048092) Streptococcus agalactiae 2603V/R 1014877 NP_689053.1 CDS SAG2067 NC_004116.1 2048136 2049020 D identified by match to PFAM protein family HMM PF00849; ribosomal large subunit pseudouridine synthase D 2048136..2049020 Streptococcus agalactiae 2603V/R 1014878 NP_689054.1 CDS SAG2068 NC_004116.1 2049045 2050685 R hypothetical protein complement(2049045..2050685) Streptococcus agalactiae 2603V/R 1014879 NP_689055.1 CDS deoB-2 NC_004116.1 2050855 2052066 R catalyzes the transfer of phosphate between the C1 and C5 carbons of pentose; phosphopentomutase complement(2050855..2052066) Streptococcus agalactiae 2603V/R 1014880 NP_689056.1 CDS deoC NC_004116.1 2052133 2052804 R catalyzes the formation of D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-D-ribose-5-phosphate; deoxyribose-phosphate aldolase complement(2052133..2052804) Streptococcus agalactiae 2603V/R 1014881 NP_689057.1 CDS SAG2071 NC_004116.1 2052834 2054036 R identified by match to PFAM protein family HMM PF01773; Na+ dependent nucleoside transporter complement(2052834..2054036) Streptococcus agalactiae 2603V/R 1014882 NP_689058.1 CDS udp NC_004116.1 2054057 2054836 R identified by match to PFAM protein family HMM PF01048; uridine phosphorylase complement(2054057..2054836) Streptococcus agalactiae 2603V/R 1014883 NP_689059.1 CDS SAG2073 NC_004116.1 2054994 2055731 D identified by match to PFAM protein family HMM PF00392; GntR family transcriptional regulator 2054994..2055731 Streptococcus agalactiae 2603V/R 1014884 YP_008592388.1 CDS SAG_RS02460 NC_004116.1 2055744 2056040 D hypothetical protein 2055744..2056040 Streptococcus agalactiae 2603V/R 17097511 NP_689060.1 CDS groEL NC_004116.1 2056140 2057762 R 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth; molecular chaperone GroEL complement(2056140..2057762) Streptococcus agalactiae 2603V/R 1014885 NP_689061.1 CDS groES NC_004116.1 2057858 2058142 R 10 kDa chaperonin; Cpn10; GroES; forms homoheptameric ring; binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it; folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES; release of the folded substrate is dependent on ATP-binding and hydrolysis in the trans ring; co-chaperonin GroES complement(2057858..2058142) Streptococcus agalactiae 2603V/R 1014886 NP_689062.1 CDS SAG2076 NC_004116.1 2058317 2059120 R identified by match to PFAM protein family HMM PF00005; ABC transporter ATP-binding protein complement(2058317..2059120) Streptococcus agalactiae 2603V/R 1014887 NP_689063.1 CDS SAG2077 NC_004116.1 2059125 2060021 R identified by match to PFAM protein family HMM PF02653; ABC transporter permease complement(2059125..2060021) Streptococcus agalactiae 2603V/R 1014888 NP_689064.1 CDS SAG2078 NC_004116.1 2060037 2060999 R similar to OMNI:SP1069; identified by sequence similarity; The product of this gene was detected by Western blot analysis. For details on the method see Tettelin et al. 2002.; hypothetical protein complement(2060037..2060999) Streptococcus agalactiae 2603V/R 1014889 NP_689065.1 CDS SAG2079 NC_004116.1 2061464 2062261 R identified by match to PFAM protein family HMM PF00702; HAD superfamily hydrolase complement(2061464..2062261) Streptococcus agalactiae 2603V/R 1014890 NP_689066.1 CDS SAG2080 NC_004116.1 2062447 2063307 D identified by match to PFAM protein family HMM PF00903; glyoxylase 2062447..2063307 Streptococcus agalactiae 2603V/R 1014891 NP_689067.1 CDS SAG2081 NC_004116.1 2063350 2064081 D hypothetical protein 2063350..2064081 Streptococcus agalactiae 2603V/R 1014892 NP_689068.1 CDS nrdG NC_004116.1 2064438 2065055 R identified by match to PFAM protein family HMM PF02143; anaerobic ribonucleoside-triphosphate reductase activating protein complement(2064438..2065055) Streptococcus agalactiae 2603V/R 1014893 NP_689069.1 CDS SAG2083 NC_004116.1 2065128 2065619 R identified by match to PFAM protein family HMM PF00583; acetyltransferase complement(2065128..2065619) Streptococcus agalactiae 2603V/R 1014894 NP_689070.1 CDS SAG2084 NC_004116.1 2065628 2066560 R identified by match to PFAM protein family HMM PF01408; virulence factor MviM complement(2065628..2066560) Streptococcus agalactiae 2603V/R 1014895 NP_689071.1 CDS SAG2085 NC_004116.1 2066573 2066716 R hypothetical protein complement(2066573..2066716) Streptococcus agalactiae 2603V/R 1014896 NP_689072.1 CDS nrdD NC_004116.1 2066791 2068962 R Catalyzes the reduction of nucleoside 5'-triphosphates to 2'-deoxynucleoside 5'-triphosphates; anaerobic ribonucleoside triphosphate reductase complement(2066791..2068962) Streptococcus agalactiae 2603V/R 1014897 NP_689073.1 CDS SAG2087 NC_004116.1 2069088 2070575 R similar to OMNI:NTL01SPL1648; identified by sequence similarity; hypothetical protein complement(2069088..2070575) Streptococcus agalactiae 2603V/R 1014898 NP_689074.1 CDS SAG2088 NC_004116.1 2070675 2070797 R hypothetical protein complement(2070675..2070797) Streptococcus agalactiae 2603V/R 1014899 NP_689075.1 CDS SAG2089 NC_004116.1 2070879 2071196 R hypothetical protein complement(2070879..2071196) Streptococcus agalactiae 2603V/R 1014900 NP_689076.1 CDS SAG2090 NC_004116.1 2071222 2071632 R similar to RuvC resolvase with substantial differences; NMR structural information suggests this protein is monomeric; unknown cellular function; Holliday junction resolvase-like protein complement(2071222..2071632) Streptococcus agalactiae 2603V/R 1014901 NP_689077.1 CDS SAG2091 NC_004116.1 2071641 2071907 R hypothetical protein complement(2071641..2071907) Streptococcus agalactiae 2603V/R 1014902 NP_689078.1 CDS spxA NC_004116.1 2072109 2072507 R the anti-alpha factor Spx interacts with RNA polymerase alpha subunit C-terminal domain in a region that interacts with the sigma 70 subunit and may interfere with activation of promoters; in Bacillus subtilis this protein is a substrate for ClpXP protease; blocks transcription of the competence regulatory gene encoded by the srf operon; regulates a number of genes involved in thiol homeostasis including trxA and trxB; monomeric member of ArsC family of proteins; does not bind DNA; contains a disulfide bond between C10 and C13 which may sense disulfide stress; Spx family transcriptional regulator complement(2072109..2072507) Streptococcus agalactiae 2603V/R 1014903 NP_689079.1 CDS recA NC_004116.1 2072723 2073862 R catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs; recombinase A complement(2072723..2073862) Streptococcus agalactiae 2603V/R 1014904 NP_689080.1 CDS tag NC_004116.1 2075285 2075836 R identified by match to PFAM protein family HMM PF03352; DNA-3-methyladenine glycosylase I complement(2075285..2075836) Streptococcus agalactiae 2603V/R 1014906 NP_689081.1 CDS ruvA NC_004116.1 2075859 2076449 R plays an essential role in ATP-dependent branch migration of the Holliday junction; Holliday junction DNA helicase RuvA complement(2075859..2076449) Streptococcus agalactiae 2603V/R 1014907 NP_689082.1 CDS SAG2097 NC_004116.1 2076451 2077707 R transporter complement(2076451..2077707) Streptococcus agalactiae 2603V/R 1014908 NP_689083.1 CDS mutL NC_004116.1 2077715 2079694 R This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. Promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex; DNA mismatch repair protein complement(2077715..2079694) Streptococcus agalactiae 2603V/R 1014909 NP_689084.1 CDS SAG2099 NC_004116.1 2079819 2079920 R hypothetical protein complement(2079819..2079920) Streptococcus agalactiae 2603V/R 1014910 NP_689085.1 CDS SAG2100 NC_004116.1 2079914 2080117 D identified by match to PFAM protein family HMM PF00313; CSD family cold shock protein 2079914..2080117 Streptococcus agalactiae 2603V/R 1014911 NP_689086.1 CDS hexA NC_004116.1 2080174 2082750 R This protein performs the mismatch recognition step during the DNA repair process; DNA mismatch repair protein MutS complement(2080174..2082750) Streptococcus agalactiae 2603V/R 1014912 NP_689087.1 CDS SAG2102 NC_004116.1 2082807 2083244 R identified by match to PFAM protein family HMM PF01316; arginine repressor ArgR complement(2082807..2083244) Streptococcus agalactiae 2603V/R 1014913 NP_689088.1 CDS argS NC_004116.1 2083466 2085157 D catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase; arginyl-tRNA synthetase 2083466..2085157 Streptococcus agalactiae 2603V/R 1014914 NP_689089.1 CDS SAG2104 NC_004116.1 2085245 2085553 D hypothetical protein 2085245..2085553 Streptococcus agalactiae 2603V/R 1014915 NP_689090.1 CDS SAG2105 NC_004116.1 2085580 2086452 R hypothetical protein complement(2085580..2086452) Streptococcus agalactiae 2603V/R 1014916 NP_689091.1 CDS SAG2106 NC_004116.1 2086560 2087504 R hypothetical protein complement(2086560..2087504) Streptococcus agalactiae 2603V/R 1014917 NP_689092.1 CDS aspS NC_004116.1 2087494 2089245 R catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes; aspartyl-tRNA synthetase complement(2087494..2089245) Streptococcus agalactiae 2603V/R 1014918 NP_689093.1 CDS hisS NC_004116.1 2089338 2090618 R catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG; histidyl-tRNA synthetase complement(2089338..2090618) Streptococcus agalactiae 2603V/R 1014919 NP_689094.1 CDS rpmF NC_004116.1 2090838 2091020 D some L32 proteins have zinc finger motifs consisting of CXXC while others do not; 50S ribosomal protein L32 2090838..2091020 Streptococcus agalactiae 2603V/R 1014920 NP_689095.1 CDS rpmG NC_004116.1 2091036 2091185 D in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif; 50S ribosomal protein L33 2091036..2091185 Streptococcus agalactiae 2603V/R 1014921 NP_689096.1 CDS SAG2111 NC_004116.1 2091333 2091854 R hypothetical protein complement(2091333..2091854) Streptococcus agalactiae 2603V/R 1014922 NP_689097.1 CDS SAG2112 NC_004116.1 2091952 2093436 R identified by match to PFAM protein family HMM PF00589; phage integrase family site specific recombinase complement(2091952..2093436) Streptococcus agalactiae 2603V/R 1014923 NP_689098.1 CDS SAG2113 NC_004116.1 2093446 2093694 R hypothetical protein complement(2093446..2093694) Streptococcus agalactiae 2603V/R 1014924 NP_689099.1 CDS SAG2114 NC_004116.1 2093760 2094788 R hypothetical protein complement(2093760..2094788) Streptococcus agalactiae 2603V/R 1014925 NP_689100.1 CDS SAG2115 NC_004116.1 2094791 2095222 R hypothetical protein complement(2094791..2095222) Streptococcus agalactiae 2603V/R 1014926 NP_689101.1 CDS SAG2116 NC_004116.1 2095498 2095953 R hypothetical protein complement(2095498..2095953) Streptococcus agalactiae 2603V/R 1014927 NP_689102.1 CDS SAG2117 NC_004116.1 2095953 2096168 R hypothetical protein complement(2095953..2096168) Streptococcus agalactiae 2603V/R 1014928 NP_689103.1 CDS SAG2118 NC_004116.1 2096491 2097411 D identified by match to PFAM protein family HMM PF01381; The product of this gene was detected by Western blot analysis. For details on the method see Tettelin et al. 2002.; Cro/CI family transcriptional regulator 2096491..2097411 Streptococcus agalactiae 2603V/R 1014929 NP_689104.1 CDS SAG2119 NC_004116.1 2097432 2098553 D similar to GP:15161770; identified by sequence similarity; hypothetical protein 2097432..2098553 Streptococcus agalactiae 2603V/R 1014930 NP_689105.1 CDS SAG2120 NC_004116.1 2098781 2099590 D hypothetical protein 2098781..2099590 Streptococcus agalactiae 2603V/R 1014931 NP_689106.1 CDS SAG2121 NC_004116.1 2100041 2100712 D identified by Glimmer2; The product of this gene was detected by Western blot analysis. For details on the method see Tettelin et al. 2002.; hypothetical protein 2100041..2100712 Streptococcus agalactiae 2603V/R 1014932 NP_689107.1 CDS SAG2122 NC_004116.1 2100797 2101468 D identified by match to PFAM protein family HMM PF00072; DNA-binding response regulator 2100797..2101468 Streptococcus agalactiae 2603V/R 1014933 NP_689108.1 CDS SAG2123 NC_004116.1 2101452 2102816 D identified by match to PFAM protein family HMM PF00512; sensor histidine kinase 2101452..2102816 Streptococcus agalactiae 2603V/R 1014934 NP_689109.1 CDS SAG2124 NC_004116.1 2102926 2104479 R hypothetical protein complement(2102926..2104479) Streptococcus agalactiae 2603V/R 1014935 NP_689110.1 CDS arcC-1 NC_004116.1 2104573 2105499 R catalyzes the reversible synthesis of carbamate and ATP from carbamoyl phosphate and ADP; carbamate kinase complement(2104573..2105499) Streptococcus agalactiae 2603V/R 1014936 NP_689111.1 CDS argF-1 NC_004116.1 2105511 2106509 R catalyzes the formation of L-citrulline from carbamoyl phosphate and L-ornithine in arginine biosynthesis and degradation; ornithine carbamoyltransferase complement(2105511..2106509) Streptococcus agalactiae 2603V/R 1014937 NP_689112.1 CDS SAG2127 NC_004116.1 2106612 2107907 D identified by match to PFAM protein family HMM PF02518; sensor histidine kinase 2106612..2107907 Streptococcus agalactiae 2603V/R 1014938 NP_689113.1 CDS SAG2128 NC_004116.1 2107904 2108737 D identified by match to PFAM protein family HMM PF00072; response regulator 2107904..2108737 Streptococcus agalactiae 2603V/R 1014939 NP_689114.1 CDS SAG2129 NC_004116.1 2108959 2109681 D identified by match to PFAM protein family HMM PF00005; amino acid ABC transporter ATP-binding protein 2108959..2109681 Streptococcus agalactiae 2603V/R 1014940 NP_689115.1 CDS SAG2130 NC_004116.1 2109684 2111198 D identified by match to PFAM protein family HMM PF00528; amino acid ABC transporter amino acid-binding protein/permease 2109684..2111198 Streptococcus agalactiae 2603V/R 1014941 NP_689116.1 CDS SAG2131 NC_004116.1 2111277 2113820 R hypothetical protein complement(2111277..2113820) Streptococcus agalactiae 2603V/R 1014942 NP_689117.1 CDS SAG2132 NC_004116.1 2113801 2114544 R hypothetical protein complement(2113801..2114544) Streptococcus agalactiae 2603V/R 1014943 NP_689118.1 CDS SAG2133 NC_004116.1 2114678 2115034 R hypothetical protein complement(2114678..2115034) Streptococcus agalactiae 2603V/R 1014944 NP_689119.1 CDS SAG2134 NC_004116.1 2115101 2117419 R similar to OMNI:NTL01SPL1699; identified by sequence similarity; hypothetical protein complement(2115101..2117419) Streptococcus agalactiae 2603V/R 1014945 NP_689120.1 CDS SAG2135 NC_004116.1 2117558 2118097 D TetR family transcriptional regulator 2117558..2118097 Streptococcus agalactiae 2603V/R 1014946 NP_689121.1 CDS SAG2136 NC_004116.1 2118183 2118479 R hypothetical protein complement(2118183..2118479) Streptococcus agalactiae 2603V/R 1014947 NP_689122.1 CDS rpsD NC_004116.1 2118723 2119334 R primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination; 30S ribosomal protein S4 complement(2118723..2119334) Streptococcus agalactiae 2603V/R 1014948 NP_689123.1 CDS SAG2138 NC_004116.1 2119664 2119951 R hypothetical protein complement(2119664..2119951) Streptococcus agalactiae 2603V/R 1014949 NP_689124.1 CDS dnaC-2 NC_004116.1 2119963 2121318 R unwinds double stranded DNA; replicative DNA helicase complement(2119963..2121318) Streptococcus agalactiae 2603V/R 1014950 NP_689125.1 CDS rplI NC_004116.1 2121361 2121813 R in Escherichia coli this protein is wrapped around the base of the L1 stalk; 50S ribosomal protein L9 complement(2121361..2121813) Streptococcus agalactiae 2603V/R 1014951 NP_689126.1 CDS SAG2141 NC_004116.1 2121819 2123801 R identified by match to PFAM protein family HMM PF01368; The product of this gene was detected by Western blot analysis. For details on the method see Tettelin et al. 2002.; DHH family protein complement(2121819..2123801) Streptococcus agalactiae 2603V/R 1014952 NP_689127.1 CDS gidA NC_004116.1 2123868 2125709 R GidA; glucose-inhibited cell division protein A; involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U) of the wobble uridine base in some tRNAs; tRNA uridine 5-carboxymethylaminomethyl modification protein GidA complement(2123868..2125709) Streptococcus agalactiae 2603V/R 1014953 NP_689128.1 CDS SAG2143 NC_004116.1 2125938 2126549 R identified by match to PFAM protein family HMM PF01914; hypothetical protein complement(2125938..2126549) Streptococcus agalactiae 2603V/R 1014954 NP_689129.1 CDS mnmA NC_004116.1 2126581 2127702 R catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs; tRNA-specific 2-thiouridylase MnmA complement(2126581..2127702) Streptococcus agalactiae 2603V/R 1014955 NP_689130.1 CDS sdhB NC_004116.1 2127948 2128616 D identified by match to PFAM protein family HMM PF01842; L-serine dehydratase, iron-sulfur-dependent subunit beta 2127948..2128616 Streptococcus agalactiae 2603V/R 1014956 NP_689131.1 CDS sdhA NC_004116.1 2128631 2129503 D identified by match to PFAM protein family HMM PF03313; L-serine dehydratase, iron-sulfur-dependent subunit alpha 2128631..2129503 Streptococcus agalactiae 2603V/R 1014957 NP_689132.1 CDS SAG2147 NC_004116.1 2129638 2130342 R similar to OMNI:NTL01SPL1712; identified by sequence similarity; The product of this gene was detected by Western blot analysis. For details on the method see Tettelin et al. 2002.; hypothetical protein complement(2129638..2130342) Streptococcus agalactiae 2603V/R 1014958 NP_689133.1 CDS SAG2148 NC_004116.1 2130448 2130987 R identified by match to PFAM protein family HMM PF01476; LysM domain-containing protein complement(2130448..2130987) Streptococcus agalactiae 2603V/R 1014959 NP_689134.1 CDS SAG2149 NC_004116.1 2131203 2131997 R identified by match to PFAM protein family HMM PF02361; cobalt transport family protein complement(2131203..2131997) Streptococcus agalactiae 2603V/R 1014960 NP_689135.1 CDS cbiO NC_004116.1 2131990 2132832 R with CbiNQ forms the ABC transporter for cobalt import; Streptococcus has two adjacent copies of this gene; cobalt transporter ATP-binding subunit complement(2131990..2132832) Streptococcus agalactiae 2603V/R 1014961 NP_689136.1 CDS cbiO NC_004116.1 2132808 2133647 R with CbiNQ forms the ABC transporter for cobalt import; Streptococcus has two adjacent copies of this gene; cobalt transporter ATP-binding subunit complement(2132808..2133647) Streptococcus agalactiae 2603V/R 1014962 NP_689137.1 CDS pgsA NC_004116.1 2133647 2134189 R identified by match to PFAM protein family HMM PF01066; CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase complement(2133647..2134189) Streptococcus agalactiae 2603V/R 1014963 NP_689138.1 CDS SAG2153 NC_004116.1 2134312 2135595 R identified by match to PFAM protein family HMM PF00675; M16 family peptidase complement(2134312..2135595) Streptococcus agalactiae 2603V/R 1014964 NP_689139.1 CDS SAG2154 NC_004116.1 2135597 2136841 R hypothetical protein complement(2135597..2136841) Streptococcus agalactiae 2603V/R 1014965 NP_689140.1 CDS SAG2155 NC_004116.1 2137080 2137433 D hypothetical protein 2137080..2137433 Streptococcus agalactiae 2603V/R 1014966 NP_689141.1 CDS recF NC_004116.1 2137436 2138545 D Required for DNA replication; binds preferentially to single-stranded, linear DNA; recombination protein F 2137436..2138545 Streptococcus agalactiae 2603V/R 1014967 NP_689142.1 CDS SAG2157 NC_004116.1 2138557 2139393 R identified by match to PFAM protein family HMM PF00892; transporter complement(2138557..2139393) Streptococcus agalactiae 2603V/R 1014968 NP_689143.1 CDS SAG2158 NC_004116.1 2139479 2140141 R identified by match to PFAM protein family HMM PF01381; Cro/CI family transcriptional regulator complement(2139479..2140141) Streptococcus agalactiae 2603V/R 1014969 NP_689144.1 CDS guaB NC_004116.1 2140216 2141697 R catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate; inosine 5'-monophosphate dehydrogenase complement(2140216..2141697) Streptococcus agalactiae 2603V/R 1014970 NP_689145.1 CDS SAG2160 NC_004116.1 2141854 2142339 R identified by match to PFAM protein family HMM PF02863; ArgR family transcriptional regulator complement(2141854..2142339) Streptococcus agalactiae 2603V/R 1014971 NP_689146.1 CDS SAG2161 NC_004116.1 2142349 2143029 R identified by match to PFAM protein family HMM PF00027; Crp/Fnr family transcriptional regulator complement(2142349..2143029) Streptococcus agalactiae 2603V/R 1014972 NP_689147.1 CDS SAG2162 NC_004116.1 2143237 2143941 D hypothetical protein 2143237..2143941 Streptococcus agalactiae 2603V/R 1014973 NP_689148.1 CDS arcA NC_004116.1 2144208 2145440 D catalyzes the degradation of arginine to citruline and ammonia; arginine deiminase 2144208..2145440 Streptococcus agalactiae 2603V/R 1014974 NP_689149.1 CDS SAG2164 NC_004116.1 2145467 2145877 D identified by match to PFAM protein family HMM PF00583; acetyltransferase 2145467..2145877 Streptococcus agalactiae 2603V/R 1014975 NP_689150.1 CDS argF-2 NC_004116.1 2145893 2146906 D catalyzes the formation of ornithine and carbamylphosphate from citrulline in the arginine catabolic pathway; ornithine carbamoyltransferase 2145893..2146906 Streptococcus agalactiae 2603V/R 1014976 NP_689151.1 CDS arcD NC_004116.1 2146969 2148396 D identified by match to PFAM protein family HMM PF00324; arginine/ornithine antiporter 2146969..2148396 Streptococcus agalactiae 2603V/R 1014977 NP_689152.1 CDS arcC-2 NC_004116.1 2148417 2149373 D catalyzes the reversible synthesis of carbamate and ATP from carbamoyl phosphate and ADP; carbamate kinase 2148417..2149373 Streptococcus agalactiae 2603V/R 1014978 NP_689153.1 CDS trpS NC_004116.1 2149483 2150508 R catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; tryptophanyl-tRNA synthetase complement(2149483..2150508) Streptococcus agalactiae 2603V/R 1014979 NP_689154.1 CDS SAG2169 NC_004116.1 2150616 2151308 R hypothetical protein complement(2150616..2151308) Streptococcus agalactiae 2603V/R 1014980 NP_689155.1 CDS SAG2170 NC_004116.1 2151552 2152424 D hypothetical protein 2151552..2152424 Streptococcus agalactiae 2603V/R 1014981 NP_689156.1 CDS SAG2171 NC_004116.1 2152490 2154109 D identified by match to PFAM protein family HMM PF00005; ABC transporter ATP-binding protein 2152490..2154109 Streptococcus agalactiae 2603V/R 1014982 NP_689157.1 CDS SAG2172 NC_004116.1 2154232 2156811 D similar to OMNI:NTL01SPL1730; identified by sequence similarity; hypothetical protein 2154232..2156811 Streptococcus agalactiae 2603V/R 1014983 NP_689158.1 CDS SAG2173 NC_004116.1 2157390 2157869 R SPOUT methyltransferase family protein; crystal structure shows homodimer; in Escherichia coli this protein methylates pseudouridine at position 1915 of the 23S ribosomal RNA; rRNA large subunit methyltransferase complement(2157390..2157869) Streptococcus agalactiae 2603V/R 1014987 NP_689159.1 CDS SAG2174 NC_004116.1 2158070 2159299 D identified by match to PFAM protein family HMM PF00089; serine protease 2158070..2159299 Streptococcus agalactiae 2603V/R 1014988 NP_689160.1 CDS SAG2175 NC_004116.1 2159397 2160170 D identified by match to PFAM protein family HMM PF02195; ParB family partitioning protein 2159397..2160170 Streptococcus agalactiae 2603V/R 1014989 tRNA-Ala-2 tRNA tRNA-Ala-2 NC_004116.1 18007 18079 D tRNA-Ala 18007..18079 Streptococcus agalactiae 2603V/R 1012736 tRNA-Val-1 tRNA tRNA-Val-1 NC_004116.1 21330 21402 D tRNA-Val 21330..21402 Streptococcus agalactiae 2603V/R 1012738 tRNA-Asp-1 tRNA tRNA-Asp-1 NC_004116.1 21405 21477 D tRNA-Asp 21405..21477 Streptococcus agalactiae 2603V/R 1012739 tRNA-Lys-2 tRNA tRNA-Lys-2 NC_004116.1 21480 21552 D tRNA-Lys 21480..21552 Streptococcus agalactiae 2603V/R 1012740 tRNA-Leu-1 tRNA tRNA-Leu-1 NC_004116.1 21562 21643 D tRNA-Leu 21562..21643 Streptococcus agalactiae 2603V/R 1012741 tRNA-Thr-1 tRNA tRNA-Thr-1 NC_004116.1 21654 21726 D tRNA-Thr 21654..21726 Streptococcus agalactiae 2603V/R 1012742 tRNA-Gly-1 tRNA tRNA-Gly-1 NC_004116.1 21760 21831 D tRNA-Gly 21760..21831 Streptococcus agalactiae 2603V/R 1012743 tRNA-Leu-2 tRNA tRNA-Leu-2 NC_004116.1 21840 21924 D tRNA-Leu 21840..21924 Streptococcus agalactiae 2603V/R 1012744 tRNA-Arg-3 tRNA tRNA-Arg-3 NC_004116.1 21936 22009 D tRNA-Arg 21936..22009 Streptococcus agalactiae 2603V/R 1012745 tRNA-Pro-1 tRNA tRNA-Pro-1 NC_004116.1 22017 22090 D tRNA-Pro 22017..22090 Streptococcus agalactiae 2603V/R 1012746 tRNA-Ala-3 tRNA tRNA-Ala-3 NC_004116.1 23838 23910 D tRNA-Ala 23838..23910 Streptococcus agalactiae 2603V/R 1012748 tRNA-Val-2 tRNA tRNA-Val-2 NC_004116.1 27161 27233 D tRNA-Val 27161..27233 Streptococcus agalactiae 2603V/R 1012750 tRNA-Asp-2 tRNA tRNA-Asp-2 NC_004116.1 27236 27308 D tRNA-Asp 27236..27308 Streptococcus agalactiae 2603V/R 1012751 tRNA-Lys-3 tRNA tRNA-Lys-3 NC_004116.1 27311 27383 D tRNA-Lys 27311..27383 Streptococcus agalactiae 2603V/R 1012752 tRNA-Leu-3 tRNA tRNA-Leu-3 NC_004116.1 27393 27474 D tRNA-Leu 27393..27474 Streptococcus agalactiae 2603V/R 1012753 tRNA-Thr-2 tRNA tRNA-Thr-2 NC_004116.1 27485 27557 D tRNA-Thr 27485..27557 Streptococcus agalactiae 2603V/R 1012754 tRNA-Gly-2 tRNA tRNA-Gly-2 NC_004116.1 27591 27662 D tRNA-Gly 27591..27662 Streptococcus agalactiae 2603V/R 1012755 tRNA-Leu-4 tRNA tRNA-Leu-4 NC_004116.1 27671 27755 D tRNA-Leu 27671..27755 Streptococcus agalactiae 2603V/R 1012756 tRNA-Arg-4 tRNA tRNA-Arg-4 NC_004116.1 27767 27840 D tRNA-Arg 27767..27840 Streptococcus agalactiae 2603V/R 1012757 tRNA-Pro-2 tRNA tRNA-Pro-2 NC_004116.1 27848 27921 D tRNA-Pro 27848..27921 Streptococcus agalactiae 2603V/R 1012758 tRNA-Met-1 tRNA tRNA-Met-1 NC_004116.1 27937 28010 D tRNA-Met 27937..28010 Streptococcus agalactiae 2603V/R 1012759 tRNA-Met-2 tRNA tRNA-Met-2 NC_004116.1 28030 28103 D tRNA-Met 28030..28103 Streptococcus agalactiae 2603V/R 1012760 tRNA-Ser-1 tRNA tRNA-Ser-1 NC_004116.1 28119 28208 D tRNA-Ser 28119..28208 Streptococcus agalactiae 2603V/R 1012761 tRNA-Met-3 tRNA tRNA-Met-3 NC_004116.1 28219 28292 D tRNA-Met 28219..28292 Streptococcus agalactiae 2603V/R 1012762 tRNA-Phe-1 tRNA tRNA-Phe-1 NC_004116.1 28295 28367 D tRNA-Phe 28295..28367 Streptococcus agalactiae 2603V/R 1012763 tRNA-Gly-3 tRNA tRNA-Gly-3 NC_004116.1 28387 28457 D tRNA-Gly 28387..28457 Streptococcus agalactiae 2603V/R 1012764 tRNA-Ile-1 tRNA tRNA-Ile-1 NC_004116.1 28492 28565 D tRNA-Ile 28492..28565 Streptococcus agalactiae 2603V/R 1012765 tRNA-Ser-2 tRNA tRNA-Ser-2 NC_004116.1 28579 28666 D tRNA-Ser 28579..28666 Streptococcus agalactiae 2603V/R 1012766 tRNA-Ala-7 tRNA tRNA-Ala-7 NC_004116.1 92815 92887 D tRNA-Ala 92815..92887 Streptococcus agalactiae 2603V/R 1012837 tRNA-Val-5 tRNA tRNA-Val-5 NC_004116.1 96138 96210 D tRNA-Val 96138..96210 Streptococcus agalactiae 2603V/R 1012839 tRNA-Asp-3 tRNA tRNA-Asp-3 NC_004116.1 96213 96285 D tRNA-Asp 96213..96285 Streptococcus agalactiae 2603V/R 1012840 tRNA-Lys-4 tRNA tRNA-Lys-4 NC_004116.1 96288 96360 D tRNA-Lys 96288..96360 Streptococcus agalactiae 2603V/R 1012841 tRNA-Leu-6 tRNA tRNA-Leu-6 NC_004116.1 96370 96451 D tRNA-Leu 96370..96451 Streptococcus agalactiae 2603V/R 1012842 tRNA-Thr-4 tRNA tRNA-Thr-4 NC_004116.1 96462 96534 D tRNA-Thr 96462..96534 Streptococcus agalactiae 2603V/R 1012843 tRNA-Ile-4 tRNA tRNA-Ile-4 NC_004116.1 96563 96639 D tRNA-Ile 96563..96639 Streptococcus agalactiae 2603V/R 1012844 tRNA-Glu-5 tRNA tRNA-Glu-5 NC_004116.1 96647 96718 D tRNA-Glu 96647..96718 Streptococcus agalactiae 2603V/R 1012845 tRNA-Ser-5 tRNA tRNA-Ser-5 NC_004116.1 96732 96821 D tRNA-Ser 96732..96821 Streptococcus agalactiae 2603V/R 1012846 tRNA-Met-5 tRNA tRNA-Met-5 NC_004116.1 96832 96905 D tRNA-Met 96832..96905 Streptococcus agalactiae 2603V/R 1012847 tRNA-Phe-3 tRNA tRNA-Phe-3 NC_004116.1 96908 96980 D tRNA-Phe 96908..96980 Streptococcus agalactiae 2603V/R 1012848 tRNA-Tyr-3 tRNA tRNA-Tyr-3 NC_004116.1 96992 97072 D tRNA-Tyr 96992..97072 Streptococcus agalactiae 2603V/R 1012849 tRNA-Trp-2 tRNA tRNA-Trp-2 NC_004116.1 97079 97149 D tRNA-Trp 97079..97149 Streptococcus agalactiae 2603V/R 1012850 tRNA-His-2 tRNA tRNA-His-2 NC_004116.1 97164 97236 D tRNA-His 97164..97236 Streptococcus agalactiae 2603V/R 1012851 tRNA-Gln-4 tRNA tRNA-Gln-4 NC_004116.1 97243 97314 D tRNA-Gln 97243..97314 Streptococcus agalactiae 2603V/R 1012852 tRNA-Leu-7 tRNA tRNA-Leu-7 NC_004116.1 97325 97408 D tRNA-Leu 97325..97408 Streptococcus agalactiae 2603V/R 1012853 tRNA-Leu-8 tRNA tRNA-Leu-8 NC_004116.1 118606 118691 D tRNA-Leu 118606..118691 Streptococcus agalactiae 2603V/R 1012877 tRNA-Ala-1 tRNA tRNA-Ala-1 NC_004116.1 166844 166916 D tRNA-Ala 166844..166916 Streptococcus agalactiae 2603V/R 1012923 tRNA-Asn-1 tRNA tRNA-Asn-1 NC_004116.1 170169 170242 D tRNA-Asn 170169..170242 Streptococcus agalactiae 2603V/R 1012926 tRNA-Ala-4 tRNA tRNA-Ala-4 NC_004116.1 251971 252043 D tRNA-Ala 251971..252043 Streptococcus agalactiae 2603V/R 1013020 tRNA-Val-3 tRNA tRNA-Val-3 NC_004116.1 255294 255366 D tRNA-Val 255294..255366 Streptococcus agalactiae 2603V/R 1013022 tRNA-Gly-4 tRNA tRNA-Gly-4 NC_004116.1 255372 255442 D tRNA-Gly 255372..255442 Streptococcus agalactiae 2603V/R 1013023 tRNA-Ile-2 tRNA tRNA-Ile-2 NC_004116.1 255479 255555 D tRNA-Ile 255479..255555 Streptococcus agalactiae 2603V/R 1013024 tRNA-Glu-3 tRNA tRNA-Glu-3 NC_004116.1 255563 255634 D tRNA-Glu 255563..255634 Streptococcus agalactiae 2603V/R 1013025 tRNA-Ser-3 tRNA tRNA-Ser-3 NC_004116.1 255648 255737 D tRNA-Ser 255648..255737 Streptococcus agalactiae 2603V/R 1013026 tRNA-Met-4 tRNA tRNA-Met-4 NC_004116.1 255748 255821 D tRNA-Met 255748..255821 Streptococcus agalactiae 2603V/R 1013027 tRNA-Phe-2 tRNA tRNA-Phe-2 NC_004116.1 255824 255896 D tRNA-Phe 255824..255896 Streptococcus agalactiae 2603V/R 1013028 tRNA-Tyr-2 tRNA tRNA-Tyr-2 NC_004116.1 255908 255988 D tRNA-Tyr 255908..255988 Streptococcus agalactiae 2603V/R 1013029 tRNA-Trp-1 tRNA tRNA-Trp-1 NC_004116.1 255995 256065 D tRNA-Trp 255995..256065 Streptococcus agalactiae 2603V/R 1013030 tRNA-His-1 tRNA tRNA-His-1 NC_004116.1 256080 256152 D tRNA-His 256080..256152 Streptococcus agalactiae 2603V/R 1013031 tRNA-Gln-3 tRNA tRNA-Gln-3 NC_004116.1 256159 256230 D tRNA-Gln 256159..256230 Streptococcus agalactiae 2603V/R 1013032 tRNA-Leu-5 tRNA tRNA-Leu-5 NC_004116.1 256241 256324 D tRNA-Leu 256241..256324 Streptococcus agalactiae 2603V/R 1013033 tRNA-Ala-5 tRNA tRNA-Ala-5 NC_004116.1 350178 350250 D tRNA-Ala 350178..350250 Streptococcus agalactiae 2603V/R 1013129 tRNA-Asn-3 tRNA tRNA-Asn-3 NC_004116.1 353503 353576 D tRNA-Asn 353503..353576 Streptococcus agalactiae 2603V/R 1013132 tRNA-Ser-4 tRNA tRNA-Ser-4 NC_004116.1 385359 385446 D tRNA-Ser 385359..385446 Streptococcus agalactiae 2603V/R 1013171 tRNA-Ala-6 tRNA tRNA-Ala-6 NC_004116.1 419322 419394 D tRNA-Ala 419322..419394 Streptococcus agalactiae 2603V/R 1013207 tRNA-Val-4 tRNA tRNA-Val-4 NC_004116.1 422645 422717 D tRNA-Val 422645..422717 Streptococcus agalactiae 2603V/R 1013209 tRNA-Gly-5 tRNA tRNA-Gly-5 NC_004116.1 422723 422793 D tRNA-Gly 422723..422793 Streptococcus agalactiae 2603V/R 1013210 tRNA-Ile-3 tRNA tRNA-Ile-3 NC_004116.1 422830 422906 D tRNA-Ile 422830..422906 Streptococcus agalactiae 2603V/R 1013211 tRNA-Glu-4 tRNA tRNA-Glu-4 NC_004116.1 422914 422985 D tRNA-Glu 422914..422985 Streptococcus agalactiae 2603V/R 1013212 tRNA-Thr-3 tRNA tRNA-Thr-3 NC_004116.1 454477 454547 R tRNA-Thr complement(454477..454547) Streptococcus agalactiae 2603V/R 1013241 tRNA-Arg-5 tRNA tRNA-Arg-5 NC_004116.1 558712 558783 D tRNA-Arg 558712..558783 Streptococcus agalactiae 2603V/R 1013348 tRNA-Arg-1 tRNA tRNA-Arg-1 NC_004116.1 1152666 1152737 R tRNA-Arg complement(1152666..1152737) Streptococcus agalactiae 2603V/R 1013954 tRNA-Gln-1 tRNA tRNA-Gln-1 NC_004116.1 1154135 1154209 R tRNA-Gln complement(1154135..1154209) Streptococcus agalactiae 2603V/R 1013956 tRNA-Tyr-1 tRNA tRNA-Tyr-1 NC_004116.1 1154215 1154295 R tRNA-Tyr complement(1154215..1154295) Streptococcus agalactiae 2603V/R 1013957 tRNA-Glu-1 tRNA tRNA-Glu-1 NC_004116.1 1366792 1366863 R tRNA-Glu complement(1366792..1366863) Streptococcus agalactiae 2603V/R 1014163 tRNA-Gln-2 tRNA tRNA-Gln-2 NC_004116.1 1366872 1366943 R tRNA-Gln complement(1366872..1366943) Streptococcus agalactiae 2603V/R 1014164 tRNA-Cys-1 tRNA tRNA-Cys-1 NC_004116.1 1833034 1833104 D tRNA-Cys 1833034..1833104 Streptococcus agalactiae 2603V/R 1014644 tRNA-Lys-1 tRNA tRNA-Lys-1 NC_004116.1 1962163 1962235 D tRNA-Lys 1962163..1962235 Streptococcus agalactiae 2603V/R 1014789 tRNA-Asn-2 tRNA tRNA-Asn-2 NC_004116.1 2156879 2156952 R tRNA-Asn complement(2156879..2156952) Streptococcus agalactiae 2603V/R 1014984 tRNA-Glu-2 tRNA tRNA-Glu-2 NC_004116.1 2156982 2157053 R tRNA-Glu complement(2156982..2157053) Streptococcus agalactiae 2603V/R 1014985 tRNA-Arg-2 tRNA tRNA-Arg-2 NC_004116.1 2157245 2157318 D tRNA-Arg 2157245..2157318 Streptococcus agalactiae 2603V/R 1014986 Sa16SA rRNA Sa16SA NC_004116.1 16404 17954 D 16S ribosomal RNA 16404..17954 Streptococcus agalactiae 2603V/R 1012735 Sa23SA rRNA Sa23SA NC_004116.1 18234 21136 D 23S ribosomal RNA 18234..21136 Streptococcus agalactiae 2603V/R 1012737 SAG_r01 rRNA SAG_r01 NC_004116.1 21210 21326 D 5S ribosomal RNA 21210..21326 Streptococcus agalactiae 2603V/R 5228961 Sa16SB rRNA Sa16SB NC_004116.1 22235 23785 D 16S ribosomal RNA 22235..23785 Streptococcus agalactiae 2603V/R 1012747 Sa23SB rRNA Sa23SB NC_004116.1 24065 26967 D 23S ribosomal RNA 24065..26967 Streptococcus agalactiae 2603V/R 1012749 SAG_r02 rRNA SAG_r02 NC_004116.1 27041 27157 D 5S ribosomal RNA 27041..27157 Streptococcus agalactiae 2603V/R 5228960 Sa16SC rRNA Sa16SC NC_004116.1 91212 92762 D 16S ribosomal RNA 91212..92762 Streptococcus agalactiae 2603V/R 1012836 Sa23SC rRNA Sa23SC NC_004116.1 93042 95944 D 23S ribosomal RNA 93042..95944 Streptococcus agalactiae 2603V/R 1012838 SAG_r03 rRNA SAG_r03 NC_004116.1 96018 96134 D 5S ribosomal RNA 96018..96134 Streptococcus agalactiae 2603V/R 5228958 Sa16SD rRNA Sa16SD NC_004116.1 165241 166791 D 16S ribosomal RNA 165241..166791 Streptococcus agalactiae 2603V/R 1012922 Sa23SD rRNA Sa23SD NC_004116.1 167071 169973 D 23S ribosomal RNA 167071..169973 Streptococcus agalactiae 2603V/R 1012924 Sa5SD rRNA Sa5SD NC_004116.1 170047 170163 D 5S ribosomal RNA 170047..170163 Streptococcus agalactiae 2603V/R 1012925 Sa16SE rRNA Sa16SE NC_004116.1 250368 251918 D 16S ribosomal RNA 250368..251918 Streptococcus agalactiae 2603V/R 1013019 Sa23SE rRNA Sa23SE NC_004116.1 252198 255100 D 23S ribosomal RNA 252198..255100 Streptococcus agalactiae 2603V/R 1013021 SAG_r04 rRNA SAG_r04 NC_004116.1 255174 255290 D 5S ribosomal RNA 255174..255290 Streptococcus agalactiae 2603V/R 5228959 Sa16SF rRNA Sa16SF NC_004116.1 348575 350125 D 16S ribosomal RNA 348575..350125 Streptococcus agalactiae 2603V/R 1013128 Sa23SF rRNA Sa23SF NC_004116.1 350405 353307 D 23S ribosomal RNA 350405..353307 Streptococcus agalactiae 2603V/R 1013130 Sa5SF rRNA Sa5SF NC_004116.1 353381 353497 D 5S ribosomal RNA 353381..353497 Streptococcus agalactiae 2603V/R 1013131 Sa16SG rRNA Sa16SG NC_004116.1 417719 419269 D 16S ribosomal RNA 417719..419269 Streptococcus agalactiae 2603V/R 1013206 Sa23SG rRNA Sa23SG NC_004116.1 419549 422451 D 23S ribosomal RNA 419549..422451 Streptococcus agalactiae 2603V/R 1013208 SAG_r05 rRNA SAG_r05 NC_004116.1 422525 422641 D 5S ribosomal RNA 422525..422641 Streptococcus agalactiae 2603V/R 5228957