-- dump date 20140620_081737 -- class Genbank::CDS -- table cds -- table main -- field 1 id -- field 2 GI -- field 3 GeneID -- field 4 chrom_position -- field 5 chromosome -- field 6 codon_start -- field 7 contig -- field 8 description -- field 9 end_pos -- field 10 gene -- field 11 gene_id -- field 12 name -- field 13 organism -- field 14 product -- field 15 protein_id -- field 16 start_pos -- field 17 strand -- field 18 taxid -- field 19 type -- header -- id GI GeneID chrom_position chromosome codon_start contig description end_pos gene gene_id name organism product protein_id start_pos strand taxid type YP_002995770.1 251781469 8111973 225..1580 1 NC_012891.1 binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication; can also affect transcription of multiple genes including itself.; chromosomal replication initiation protein 1580 dnaA 8111973 dnaA Streptococcus dysgalactiae subsp. equisimilis GGS_124 chromosomal replication initiation protein YP_002995770.1 225 D 486410 CDS YP_002995771.1 251781470 8111842 1734..2870 1 NC_012891.1 binds the polymerase to DNA and acts as a sliding clamp; DNA polymerase III subunit beta 2870 dnaN 8111842 dnaN Streptococcus dysgalactiae subsp. equisimilis GGS_124 DNA polymerase III subunit beta YP_002995771.1 1734 D 486410 CDS YP_002995772.1 251781471 8111850 2944..3141 1 NC_012891.1 similar to hypothetical cytosolic protein [Streptococcus pyogenes MGAS10394]; hypothetical protein 3141 8111850 SDEG_0003 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002995772.1 2944 D 486410 CDS YP_002995773.1 251781472 8110853 3398..3640 1 NC_012891.1 similar to hypothetical protein gbs0005 [Streptococcus agalactiae NEM316]; hypothetical protein 3640 8110853 SDEG_0004 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002995773.1 3398 D 486410 CDS YP_002995774.1 251781473 8110854 3764..4879 1 NC_012891.1 translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1; GTP-dependent nucleic acid-binding protein EngD 4879 8110854 SDEG_0005 Streptococcus dysgalactiae subsp. equisimilis GGS_124 GTP-dependent nucleic acid-binding protein EngD YP_002995774.1 3764 D 486410 CDS YP_002995775.1 251781474 8110855 4950..5519 1 NC_012891.1 Enables the recycling of peptidyl-tRNAs produced at termination of translation; peptidyl-tRNA hydrolase 5519 pth 8110855 pth Streptococcus dysgalactiae subsp. equisimilis GGS_124 peptidyl-tRNA hydrolase YP_002995775.1 4950 D 486410 CDS YP_002995776.1 251781475 8111322 5522..9022 1 NC_012891.1 similar to transcription-repair coupling factor [Streptococcus pyogenes SSI-1]; transcription-repair coupling factor 9022 trcF 8111322 trcF Streptococcus dysgalactiae subsp. equisimilis GGS_124 transcription-repair coupling factor YP_002995776.1 5522 D 486410 CDS YP_002995777.1 251781476 8111924 8970..10490 1 NC_012891.1 similar to polysaccharide biosynthesis family protein [Streptococcus equi subsp. zooepidemicus MGCS10565]; polysaccharide biosynthesis protein 10490 8111924 SDEG_0008 Streptococcus dysgalactiae subsp. equisimilis GGS_124 polysaccharide biosynthesis protein YP_002995777.1 8970 D 486410 CDS YP_002995778.1 251781477 8110856 10525..10797 1 NC_012891.1 similar to S4 domain protein [Streptococcus agalactiae 2603V/R]; S4 domain-containing protein 10797 8110856 SDEG_0009 Streptococcus dysgalactiae subsp. equisimilis GGS_124 S4 domain-containing protein YP_002995778.1 10525 D 486410 CDS YP_002995779.1 251781478 8110857 10784..11155 1 NC_012891.1 similar to cell division protein [Streptococcus pyogenes MGAS8232]; cell division protein 11155 divIC 8110857 divIC Streptococcus dysgalactiae subsp. equisimilis GGS_124 cell division protein YP_002995779.1 10784 D 486410 CDS YP_002995780.1 251781479 8111674 11155..11277 1 NC_012891.1 similar to hypothetical protein M6 Spy0009 [Streptococcus pyogenes MGAS10394]; hypothetical protein 11277 8111674 SDEG_0011 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002995780.1 11155 D 486410 CDS YP_002995781.1 251781480 8110858 11290..12576 1 NC_012891.1 similar to beta-lactamase [Streptococcus pyogenes MGAS2096]; beta-lactamase 12576 8110858 SDEG_0012 Streptococcus dysgalactiae subsp. equisimilis GGS_124 beta-lactamase YP_002995781.1 11290 D 486410 CDS YP_002995782.1 251781481 8110859 12573..13859 1 NC_012891.1 similar to tRNA(Ile)-lysidine synthetase [Streptococcus pyogenes MGAS10394]; tRNA(Ile)-lysidine synthetase 13859 tilS 8110859 tilS Streptococcus dysgalactiae subsp. equisimilis GGS_124 tRNA(Ile)-lysidine synthetase YP_002995782.1 12573 D 486410 CDS YP_002995783.1 251781482 8110523 13864..14406 1 NC_012891.1 similar to hypoxanthine- guaninephosphoribosyltransferase [Streptococcus pyogenesMGAS8232]; hypoxanthine-guanine phosphoribosyl transferase 14406 hpt 8110523 hpt Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypoxanthine-guanine phosphoribosyl transferase YP_002995783.1 13864 D 486410 CDS YP_002995784.1 251781483 8112036 14428..16413 1 NC_012891.1 similar to cell division protein [Streptococcus pyogenes MGAS6180]; cell division protein 16413 ftsH 8112036 ftsH Streptococcus dysgalactiae subsp. equisimilis GGS_124 cell division protein YP_002995784.1 14428 D 486410 CDS YP_002995785.1 251781484 8111916 16541..17956 1 NC_012891.1 similar to amino acid permease [Streptococcus pyogenes MGAS10394]; amino acid permease 17956 8111916 SDEG_0016 Streptococcus dysgalactiae subsp. equisimilis GGS_124 amino acid permease YP_002995785.1 16541 D 486410 CDS YP_002995786.1 251781485 8111772 27115..28317 1 NC_012891.1 similar to secreted protein [Streptococcus pyogenes MGAS2096]; hypothetical protein 28317 sibA 8111772 sibA Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002995786.1 27115 D 486410 CDS YP_002995787.1 251781486 8110484 28471..29433 1 NC_012891.1 catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP; ribose-phosphate pyrophosphokinase 29433 prs1 8110484 prs1 Streptococcus dysgalactiae subsp. equisimilis GGS_124 ribose-phosphate pyrophosphokinase YP_002995787.1 28471 D 486410 CDS YP_002995788.1 251781487 8111313 29658..30422 1 NC_012891.1 involved in DNA repair and RecFOR pathway recombination; RecFOR proteins displace ssDNA-binding protein and facilitate the production of RecA-coated ssDNA; DNA repair protein RecO 30422 recO 8111313 recO Streptococcus dysgalactiae subsp. equisimilis GGS_124 DNA repair protein RecO YP_002995788.1 29658 D 486410 CDS YP_002995789.1 251781488 8111037 30529..31536 1 NC_012891.1 involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsY; glycerol-3-phosphate acyltransferase PlsX 31536 plsX 8111037 plsX Streptococcus dysgalactiae subsp. equisimilis GGS_124 glycerol-3-phosphate acyltransferase PlsX YP_002995789.1 30529 D 486410 CDS YP_002995790.1 251781489 8111296 31529..31771 1 NC_012891.1 carries the fatty acid chain in fatty acid biosynthesis; acyl carrier protein 31771 acpP.1 8111296 acpP.1 Streptococcus dysgalactiae subsp. equisimilis GGS_124 acyl carrier protein YP_002995790.1 31529 D 486410 CDS YP_002995791.1 251781490 8112304 31936..32646 1 NC_012891.1 catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis; SAICAR synthase; phosphoribosylaminoimidazolesuccinocarboxamide synthase 32646 purC 8112304 purC Streptococcus dysgalactiae subsp. equisimilis GGS_124 phosphoribosylaminoimidazolesuccinocarboxamide synthase YP_002995791.1 31936 D 486410 CDS YP_002995792.1 251781491 8111332 32855..36580 1 NC_012891.1 similar to phosphoribosyl formyl glycinamidine synthase [Streptococcus pyogenes MGAS2096]; phosphoribosyl formylglycin amidine synthase 36580 8111332 SDEG_0044 Streptococcus dysgalactiae subsp. equisimilis GGS_124 phosphoribosyl formylglycin amidine synthase YP_002995792.1 32855 D 486410 CDS YP_002995793.1 251781492 8111773 36699..38150 1 NC_012891.1 Catalyzes first step of the de novo purine nucleotide biosynthetic pathway; amidophosphoribosyltransferase 38150 purF 8111773 purF Streptococcus dysgalactiae subsp. equisimilis GGS_124 amidophosphoribosyltransferase YP_002995793.1 36699 D 486410 CDS YP_002995794.1 251781493 8111334 38300..39331 1 NC_012891.1 catalyzes the formation of 1-(5-phosphoribosyl)-5-aminoimidazole from 2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in purine biosynthesis; phosphoribosylaminoimidazole synthetase 39331 8111334 SDEG_0046 Streptococcus dysgalactiae subsp. equisimilis GGS_124 phosphoribosylaminoimidazole synthetase YP_002995794.1 38300 D 486410 CDS YP_002995795.1 251781494 8111774 39324..39878 1 NC_012891.1 glycinamide ribonucleotide transformylase; GAR Tfase; catalyzes the synthesis of 5'-phosphoribosylformylglycinamide from 5'-phosphoribosylglycinamide and 10-formyltetrahydrofolate; PurN requires formyl folate for the reaction unlike PurT which uses formate; phosphoribosylglycinamide formyltransferase 39878 purN 8111774 purN Streptococcus dysgalactiae subsp. equisimilis GGS_124 phosphoribosylglycinamide formyltransferase YP_002995795.1 39324 D 486410 CDS YP_002995796.1 251781495 8111335 39976..40497 1 NC_012891.1 similar to vanZ protein [Streptococcus pneumoniae TIGR4]; vanZ protein 40497 8111335 SDEG_0048 Streptococcus dysgalactiae subsp. equisimilis GGS_124 vanZ protein YP_002995796.1 39976 D 486410 CDS YP_002995797.1 251781496 8111775 40516..42060 1 NC_012891.1 involved in de novo purine biosynthesis; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 42060 purH 8111775 purH Streptococcus dysgalactiae subsp. equisimilis GGS_124 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase YP_002995797.1 40516 D 486410 CDS YP_002995798.1 251781497 8111776 complement(42140..43267) 1 NC_012891.1 similar to autolysin [Streptococcus pyogenes MGAS5005]; autolysin 43267 8111776 SDEG_0050 Streptococcus dysgalactiae subsp. equisimilis GGS_124 autolysin YP_002995798.1 42140 R 486410 CDS YP_002995799.1 251781498 8111777 43551..44813 1 NC_012891.1 catalyzes the formation of N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-D-ribosylamine and glycine in purine biosynthesis; phosphoribosylamine--glycine ligase 44813 purD 8111777 purD Streptococcus dysgalactiae subsp. equisimilis GGS_124 phosphoribosylamine--glycine ligase YP_002995799.1 43551 D 486410 CDS YP_002995800.1 251781499 8111333 45452..45940 1 NC_012891.1 similar to phosphoribosyl carboxyaminoimidazole (NCAIR) mutase [Streptococcus suis 98HAH33]; phosphoribosyl carboxyaminoimidazole (NCAIR) mutase 45940 8111333 SDEG_0052 Streptococcus dysgalactiae subsp. equisimilis GGS_124 phosphoribosyl carboxyaminoimidazole (NCAIR) mutase YP_002995800.1 45452 D 486410 CDS YP_002995801.1 251781500 8111778 45927..47000 1 NC_012891.1 With PurE catalyzes the conversion of aminoimidazole ribonucleotide to carboxyaminoimidazole ribonucleotide in the de novo purine nucleotide biosynthetic pathway; phosphoribosylaminoimidazole carboxylase ATPase subunit 47000 8111778 SDEG_0053 Streptococcus dysgalactiae subsp. equisimilis GGS_124 phosphoribosylaminoimidazole carboxylase ATPase subunit YP_002995801.1 45927 D 486410 CDS YP_002995802.1 251781501 8111779 47010..48266 1 NC_012891.1 similar to hypothetical protein SGO 2086 [Streptococcus gordonii str. Challis substr. CH1]; hypothetical protein 48266 8111779 SDEG_0054 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002995802.1 47010 D 486410 CDS YP_002995803.1 251781502 8111780 48517..49809 1 NC_012891.1 Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide; adenylosuccinate lyase 49809 purB 8111780 purB Streptococcus dysgalactiae subsp. equisimilis GGS_124 adenylosuccinate lyase YP_002995803.1 48517 D 486410 CDS YP_002995804.1 251781503 8111331 49951..50862 1 NC_012891.1 similar to transcriptional regulator [Streptococcus pyogenes MGAS10750]; transcriptional regulator 50862 8111331 SDEG_0056 Streptococcus dysgalactiae subsp. equisimilis GGS_124 transcriptional regulator YP_002995804.1 49951 D 486410 CDS YP_002995805.1 251781504 8111781 51079..52095 1 NC_012891.1 promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration; Holliday junction DNA helicase RuvB 52095 ruvB 8111781 ruvB Streptococcus dysgalactiae subsp. equisimilis GGS_124 Holliday junction DNA helicase RuvB YP_002995805.1 51079 D 486410 CDS YP_002995806.1 251781505 8110452 52230..52661 1 NC_012891.1 similar to protein tyrosine phosphatase [Streptococcus pyogenes MGAS10270]; protein tyrosine phosphatase 52661 8110452 SDEG_0058 Streptococcus dysgalactiae subsp. equisimilis GGS_124 protein tyrosine phosphatase YP_002995806.1 52230 D 486410 CDS YP_002995807.1 251781506 8111782 52690..53091 1 NC_012891.1 similar to hypothetical membrane associated protein [Streptococcus pyogenes MGAS2096]; hypothetical protein 53091 8111782 SDEG_0059 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002995807.1 52690 D 486410 CDS YP_002995808.1 251781507 8111783 53088..54863 1 NC_012891.1 similar to acyltransferase family [Streptococcus pyogenes MGAS6180]; acyltransferase family 54863 8111783 SDEG_0060 Streptococcus dysgalactiae subsp. equisimilis GGS_124 acyltransferase family YP_002995808.1 53088 D 486410 CDS YP_002995809.1 251781508 8111784 55184..57826 1 NC_012891.1 similar to alcohol dehydrogenase/acetaldehyde dehydrogenase (acetylating) [Streptococcus pyogenes MGAS5005]; bifunctional acetaldehyde-CoA/alcohol dehydrogenase 57826 adh2 8111784 adh2 Streptococcus dysgalactiae subsp. equisimilis GGS_124 bifunctional acetaldehyde-CoA/alcohol dehydrogenase YP_002995809.1 55184 D 486410 CDS YP_002995810.1 251781509 8112311 58119..59135 1 NC_012891.1 similar to zinc-dependent eukaryotic ADH enzymes and distinct from fermentative ADHs; alcohol dehydrogenase 59135 adhA 8112311 adhA Streptococcus dysgalactiae subsp. equisimilis GGS_124 alcohol dehydrogenase YP_002995810.1 58119 D 486410 CDS YP_002995811.1 251781510 8112312 59327..60811 1 NC_012891.1 catalyzes the formation of L-threonine from O-phospho-L-homoserine; threonine synthase 60811 thnsl 8112312 thnsl Streptococcus dysgalactiae subsp. equisimilis GGS_124 threonine synthase YP_002995811.1 59327 D 486410 CDS YP_002995812.1 251781511 8110519 60851..62140 1 NC_012891.1 similar to Na+ driven multidrug efflux pump [Streptococcus pyogenes MGAS10394]; Na+ driven multidrug efflux pump 62140 8110519 SDEG_0064 Streptococcus dysgalactiae subsp. equisimilis GGS_124 Na+ driven multidrug efflux pump YP_002995812.1 60851 D 486410 CDS YP_002995813.1 251781512 8111785 complement(62109..63032) 1 NC_012891.1 similar to transposase [Streptococcus pyogenes MGAS10394]; transposase 63032 8111785 SDEG_0065 Streptococcus dysgalactiae subsp. equisimilis GGS_124 transposase YP_002995813.1 62109 R 486410 CDS YP_002995814.1 251781513 8111786 complement(62861..63184) 1 NC_012891.1 similar to transposase [Streptococcus pyogenes MGAS8232]; transposase 63184 8111786 SDEG_0066 Streptococcus dysgalactiae subsp. equisimilis GGS_124 transposase YP_002995814.1 62861 R 486410 CDS YP_002995815.1 251781514 8111787 63493..63801 1 NC_012891.1 NusE; involved in assembly of the 30S subunit; in the ribosome, this protein is involved in the binding of tRNA; in Escherichia coli this protein was also found to be involved in transcription antitermination; NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination; binding of NusB/S10 to boxA nucleates assembly of the antitermination complex; 30S ribosomal protein S10 63801 rpsJ 8111787 rpsJ Streptococcus dysgalactiae subsp. equisimilis GGS_124 30S ribosomal protein S10 YP_002995815.1 63493 D 486410 CDS YP_002995816.1 251781515 8111101 63907..64533 1 NC_012891.1 binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin; 50S ribosomal protein L3 64533 rplC 8111101 rplC Streptococcus dysgalactiae subsp. equisimilis GGS_124 50S ribosomal protein L3 YP_002995816.1 63907 D 486410 CDS YP_002995817.1 251781516 8111060 64557..65180 1 NC_012891.1 L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA; 50S ribosomal protein L4 65180 rplD 8111060 rplD Streptococcus dysgalactiae subsp. equisimilis GGS_124 50S ribosomal protein L4 YP_002995817.1 64557 D 486410 CDS YP_002995818.1 251781517 8111061 65180..65476 1 NC_012891.1 binds third domain of 23S rRNA and protein L29; part of exit tunnel; 50S ribosomal protein L23 65476 rplW 8111061 rplW Streptococcus dysgalactiae subsp. equisimilis GGS_124 50S ribosomal protein L23 YP_002995818.1 65180 D 486410 CDS YP_002995819.1 251781518 8111077 65494..66327 1 NC_012891.1 one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation; 50S ribosomal protein L2 66327 rplB 8111077 rplB Streptococcus dysgalactiae subsp. equisimilis GGS_124 50S ribosomal protein L2 YP_002995819.1 65494 D 486410 CDS YP_002995820.1 251781519 8111059 66418..66744 1 NC_012891.1 similar to SSU ribosomal protein S19P [Streptococcus pyogenes MGAS2096]; 30S ribosomal protein S19 66744 rpsS 8111059 rpsS Streptococcus dysgalactiae subsp. equisimilis GGS_124 30S ribosomal protein S19 YP_002995820.1 66418 D 486410 CDS YP_002995821.1 251781520 8111110 66760..67104 1 NC_012891.1 binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center; 50S ribosomal protein L22 67104 rplV 8111110 rplV Streptococcus dysgalactiae subsp. equisimilis GGS_124 50S ribosomal protein L22 YP_002995821.1 66760 D 486410 CDS YP_002995822.1 251781521 8111076 67117..67770 1 NC_012891.1 forms a complex with S10 and S14; binds the lower part of the 30S subunit head and the mRNA in the complete ribosome to position it for translation; 30S ribosomal protein S3 67770 rpsC 8111076 rpsC Streptococcus dysgalactiae subsp. equisimilis GGS_124 30S ribosomal protein S3 YP_002995822.1 67117 D 486410 CDS YP_002995823.1 251781522 8111788 67774..68187 1 NC_012891.1 located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e; 50S ribosomal protein L16 68187 rplP 8111788 rplP Streptococcus dysgalactiae subsp. equisimilis GGS_124 50S ribosomal protein L16 YP_002995823.1 67774 D 486410 CDS YP_002995824.1 251781523 8111789 68197..68403 1 NC_012891.1 one of the stabilizing components for the large ribosomal subunit; 50S ribosomal protein L29 68403 8111789 SDEG_0076 Streptococcus dysgalactiae subsp. equisimilis GGS_124 50S ribosomal protein L29 YP_002995824.1 68197 D 486410 CDS YP_002995825.1 251781524 8111790 68431..68691 1 NC_012891.1 primary binding protein; helps mediate assembly; involved in translation fidelity; 30S ribosomal protein S17 68691 rpsQ 8111790 rpsQ Streptococcus dysgalactiae subsp. equisimilis GGS_124 30S ribosomal protein S17 YP_002995825.1 68431 D 486410 CDS YP_002995826.1 251781525 8111791 68716..69084 1 NC_012891.1 binds to the 23S rRNA between the centers for peptidyl transferase and GTPase; 50S ribosomal protein L14 69084 rplN 8111791 rplN Streptococcus dysgalactiae subsp. equisimilis GGS_124 50S ribosomal protein L14 YP_002995826.1 68716 D 486410 CDS YP_002995827.1 251781526 8111068 complement(68721..68987) 1 NC_012891.1 similar to 50S ribosomal protein L14 [Staphylococcus epidermidis ATCC 12228]; 50S ribosomal protein L14 68987 8111068 SDEG_0079 Streptococcus dysgalactiae subsp. equisimilis GGS_124 50S ribosomal protein L14 YP_002995827.1 68721 R 486410 CDS YP_002995828.1 251781527 8111792 69168..69473 1 NC_012891.1 assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel; 50S ribosomal protein L24 69473 rplX 8111792 rplX Streptococcus dysgalactiae subsp. equisimilis GGS_124 50S ribosomal protein L24 YP_002995828.1 69168 D 486410 CDS YP_002995829.1 251781528 8111078 69497..70039 1 NC_012891.1 part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13; 50S ribosomal protein L5 70039 rplE 8111078 rplE Streptococcus dysgalactiae subsp. equisimilis GGS_124 50S ribosomal protein L5 YP_002995829.1 69497 D 486410 CDS YP_002995830.1 251781529 8111062 70055..70240 1 NC_012891.1 located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group appear to contain the zinc-binding motif; 30S ribosomal protein S14 70240 rpsN 8111062 rpsN Streptococcus dysgalactiae subsp. equisimilis GGS_124 30S ribosomal protein S14 YP_002995830.1 70055 D 486410 CDS YP_002995831.1 251781530 8111105 70448..70846 1 NC_012891.1 binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; 30S ribosomal protein S8 70846 rpsH 8111105 rpsH Streptococcus dysgalactiae subsp. equisimilis GGS_124 30S ribosomal protein S8 YP_002995831.1 70448 D 486410 CDS YP_002995832.1 251781531 8111099 71048..71584 1 NC_012891.1 ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance; 50S ribosomal protein L6 71584 rplF 8111099 rplF Streptococcus dysgalactiae subsp. equisimilis GGS_124 50S ribosomal protein L6 YP_002995832.1 71048 D 486410 CDS YP_002995833.1 251781532 8111063 71680..72045 1 NC_012891.1 binds 5S rRNA along with protein L5 and L25; 50S ribosomal protein L18 72045 rplR 8111063 rplR Streptococcus dysgalactiae subsp. equisimilis GGS_124 50S ribosomal protein L18 YP_002995833.1 71680 D 486410 CDS YP_002995834.1 251781533 8111071 complement(71857..72309) 1 NC_012891.1 similar to conserved hypothetical protein [Listeria monocytogenes str. 4b H7858]; hypothetical protein 72309 8111071 SDEG_0086 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002995834.1 71857 R 486410 CDS YP_002995835.1 251781534 8111793 72064..72558 1 NC_012891.1 located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance; 30S ribosomal protein S5 72558 rpsE 8111793 rpsE Streptococcus dysgalactiae subsp. equisimilis GGS_124 30S ribosomal protein S5 YP_002995835.1 72064 D 486410 CDS YP_002995836.1 251781535 8111096 complement(72315..72629) 1 NC_012891.1 similar to ribosomal protein [Streptococcus agalactiae CJB111]; ribosomal protein 72629 8111096 SDEG_0088 Streptococcus dysgalactiae subsp. equisimilis GGS_124 ribosomal protein YP_002995836.1 72315 R 486410 CDS YP_002995837.1 251781536 8111794 72573..72755 1 NC_012891.1 L30 binds domain II of the 23S rRNA and the 5S rRNA; similar to eukaryotic protein L7; 50S ribosomal protein L30 72755 rpmD 8111794 rpmD Streptococcus dysgalactiae subsp. equisimilis GGS_124 50S ribosomal protein L30 YP_002995837.1 72573 D 486410 CDS YP_002995838.1 251781537 8111081 72970..73410 1 NC_012891.1 late assembly protein; 50S ribosomal protein L15 73410 rplO 8111081 rplO Streptococcus dysgalactiae subsp. equisimilis GGS_124 50S ribosomal protein L15 YP_002995838.1 72970 D 486410 CDS YP_002995839.1 251781538 8111069 73388..74731 1 NC_012891.1 forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase; preprotein translocase subunit SecY 74731 secY 8111069 secY Streptococcus dysgalactiae subsp. equisimilis GGS_124 preprotein translocase subunit SecY YP_002995839.1 73388 D 486410 CDS YP_002995840.1 251781539 8110480 74878..75519 1 NC_012891.1 similar to adenylate kinase Adk [Streptococcus equi subsp. zooepidemicus MGCS10565]; adenylate kinase 75519 adk 8110480 adk Streptococcus dysgalactiae subsp. equisimilis GGS_124 adenylate kinase YP_002995840.1 74878 D 486410 CDS YP_002995841.1 251781540 8112313 75583..75855 1 NC_012891.1 stimulates the activities of the other two initiation factors, IF-2 and IF-3; translation initiation factor IF-1 75855 infA 8112313 infA Streptococcus dysgalactiae subsp. equisimilis GGS_124 translation initiation factor IF-1 YP_002995841.1 75583 D 486410 CDS YP_002995842.1 251781541 8112051 75881..75997 1 NC_012891.1 smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group have the motif; 50S ribosomal protein L36 75997 rpmJ 8112051 rpmJ Streptococcus dysgalactiae subsp. equisimilis GGS_124 50S ribosomal protein L36 YP_002995842.1 75881 D 486410 CDS YP_002995843.1 251781542 8111088 76015..76380 1 NC_012891.1 located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA; 30S ribosomal protein S13 76380 rpsM 8111088 rpsM Streptococcus dysgalactiae subsp. equisimilis GGS_124 30S ribosomal protein S13 YP_002995843.1 76015 D 486410 CDS YP_002995844.1 251781543 8111104 76398..76781 1 NC_012891.1 located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3; 30S ribosomal protein S11 76781 rpsK 8111104 rpsK Streptococcus dysgalactiae subsp. equisimilis GGS_124 30S ribosomal protein S11 YP_002995844.1 76398 D 486410 CDS YP_002995845.1 251781544 8111102 76827..77765 1 NC_012891.1 catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme; DNA-directed RNA polymerase subunit alpha 77765 rpoA 8111102 rpoA Streptococcus dysgalactiae subsp. equisimilis GGS_124 DNA-directed RNA polymerase subunit alpha YP_002995845.1 76827 D 486410 CDS YP_002995846.1 251781545 8111089 77780..78166 1 NC_012891.1 is a component of the macrolide binding site in the peptidyl transferase center; 50S ribosomal protein L17 78166 rplQ 8111089 rplQ Streptococcus dysgalactiae subsp. equisimilis GGS_124 50S ribosomal protein L17 YP_002995846.1 77780 D 486410 CDS YP_002995847.1 251781546 8111070 78646..79482 1 NC_012891.1 similar to transposase [Streptococcus pyogenes MGAS10394]; transposase 79482 8111070 SDEG_0099 Streptococcus dysgalactiae subsp. equisimilis GGS_124 transposase YP_002995847.1 78646 D 486410 CDS YP_002995848.1 251781547 8111795 79570..80598 1 NC_012891.1 similar to transposase [Streptococcus pyogenes MGAS10270]; transposase 80598 8111795 SDEG_0100 Streptococcus dysgalactiae subsp. equisimilis GGS_124 transposase YP_002995848.1 79570 D 486410 CDS YP_002995849.1 251781548 8111812 87208..87747 1 NC_012891.1 similar to nudix hydrolase [Streptococcus equi subsp. zooepidemicus MGCS10565]; nudix hydrolase 87747 8111812 SDEG_0117 Streptococcus dysgalactiae subsp. equisimilis GGS_124 nudix hydrolase YP_002995849.1 87208 D 486410 CDS YP_002995850.1 251781549 8111813 87882..88781 1 NC_012891.1 catalyzes the formation of dimethylmenaquinone from 1,4-dihydroxy-2-naphthoate and octaprenyl diphosphate; 1,4-dihydroxy-2-naphthoate octaprenyltransferase 88781 8111813 SDEG_0118 Streptococcus dysgalactiae subsp. equisimilis GGS_124 1,4-dihydroxy-2-naphthoate octaprenyltransferase YP_002995850.1 87882 D 486410 CDS YP_002995851.1 251781550 8111814 88778..90004 1 NC_012891.1 similar to hypothetical protein gbs1788 [Streptococcus agalactiae NEM316]; hypothetical protein 90004 8111814 SDEG_0119 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002995851.1 88778 D 486410 CDS YP_002995852.1 251781551 8111815 90114..91541 1 NC_012891.1 similar to cytochrome d ubiquinol oxidase subunit II [Streptococcus agalactiae A909]; cytochrome d ubiquinol oxidase, subunit II 91541 cydA 8111815 cydA Streptococcus dysgalactiae subsp. equisimilis GGS_124 cytochrome d ubiquinol oxidase, subunit II YP_002995852.1 90114 D 486410 CDS YP_002995853.1 251781552 8111655 91542..92561 1 NC_012891.1 similar to cytochrome d ubiquinol oxidase subunit II [Streptococcus agalactiae 2603V/R]; cytochrome d ubiquinol oxidase, subunit II 92561 cydB 8111655 cydB Streptococcus dysgalactiae subsp. equisimilis GGS_124 cytochrome d ubiquinol oxidase, subunit II YP_002995853.1 91542 D 486410 CDS YP_002995854.1 251781553 8111656 92561..94276 1 NC_012891.1 similar to hypothetical protein gbs1785 [Streptococcus agalactiae NEM316]; hypothetical protein 94276 8111656 SDEG_0122 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002995854.1 92561 D 486410 CDS YP_002995855.1 251781554 8111816 94273..96021 1 NC_012891.1 similar to hypothetical protein gbs1784 [Streptococcus agalactiae NEM316]; hypothetical protein 96021 8111816 SDEG_0123 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002995855.1 94273 D 486410 CDS YP_002995856.1 251781555 8111817 complement(96086..97066) 1 NC_012891.1 similar to hypothetical protein gbs1783 [Streptococcus agalactiae NEM316]; hypothetical protein 97066 8111817 SDEG_0124 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002995856.1 96086 R 486410 CDS YP_002995857.1 251781556 8111818 97322..98173 1 NC_012891.1 An essential enzyme in the nonmevalonate pathway of isopentenyl diphosphate and dimethylallyl diphosphate biosynthesis; 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase 98173 ipk 8111818 ipk Streptococcus dysgalactiae subsp. equisimilis GGS_124 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase YP_002995857.1 97322 D 486410 CDS YP_002995858.1 251781557 8110875 98242..98685 1 NC_012891.1 similar to repressor protein [Streptococcus pyogenes MGAS315]; repressor protein 98685 adcR 8110875 adcR Streptococcus dysgalactiae subsp. equisimilis GGS_124 repressor protein YP_002995858.1 98242 D 486410 CDS YP_002995859.1 251781558 8112309 98689..99408 1 NC_012891.1 similar to ABC transporter (ATP-binding protein) [Streptococcus pyogenes MGAS315]; ABC transporter 99408 adcC 8112309 adcC Streptococcus dysgalactiae subsp. equisimilis GGS_124 ABC transporter YP_002995859.1 98689 D 486410 CDS YP_002995860.1 251781559 8112308 99362..100213 1 NC_012891.1 similar to high-affinity zinc uptake system membrane protein znuB [Streptococcus pyogenes MGAS2096]; high-affinity zinc uptake system membrane protein 100213 adcB 8112308 adcB Streptococcus dysgalactiae subsp. equisimilis GGS_124 high-affinity zinc uptake system membrane protein YP_002995860.1 99362 D 486410 CDS YP_002995861.1 251781560 8112307 complement(100262..101518) 1 NC_012891.1 catalyzes the formation of tyrosyl-tRNA(Tyr) from tyrosine and tRNA(Tyr); tyrosyl-tRNA synthetase 101518 tyrS 8112307 tyrS Streptococcus dysgalactiae subsp. equisimilis GGS_124 tyrosyl-tRNA synthetase YP_002995861.1 100262 R 486410 CDS YP_002995862.1 251781561 8111937 101613..103925 1 NC_012891.1 similar to multimodular transpeptidase-transglycosylase [Streptococcus pyogenes MGAS10394]; multimodular transpeptidase-transglycosylase 103925 8111937 SDEG_0130 Streptococcus dysgalactiae subsp. equisimilis GGS_124 multimodular transpeptidase-transglycosylase YP_002995862.1 101613 D 486410 CDS YP_002995863.1 251781562 8111819 104189..107755 1 NC_012891.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme; DNA-directed RNA polymerase subunit beta 107755 rpoB 8111819 rpoB Streptococcus dysgalactiae subsp. equisimilis GGS_124 DNA-directed RNA polymerase subunit beta YP_002995863.1 104189 D 486410 CDS YP_002995864.1 251781563 8111090 107851..111492 1 NC_012891.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Subunit beta' binds to sigma factor allowing it to bind to the -10 region of the promoter; DNA-directed RNA polymerase subunit beta' 111492 rpoC 8111090 rpoC Streptococcus dysgalactiae subsp. equisimilis GGS_124 DNA-directed RNA polymerase subunit beta' YP_002995864.1 107851 D 486410 CDS YP_002995865.1 251781564 8111091 111695..112060 1 NC_012891.1 similar to DNA binding protein [Streptococcus pyogenes MGAS8232]; DNA-binding protein 112060 8111091 SDEG_0133 Streptococcus dysgalactiae subsp. equisimilis GGS_124 DNA-binding protein YP_002995865.1 111695 D 486410 CDS YP_002995866.1 251781565 8111820 112141..113082 1 NC_012891.1 similar to ComG operon protein 1 [Streptococcus pyogenes MGAS10394]; ComG operon protein 1 113082 8111820 SDEG_0134 Streptococcus dysgalactiae subsp. equisimilis GGS_124 ComG operon protein 1 YP_002995866.1 112141 D 486410 CDS YP_002995867.1 251781566 8111821 112958..114049 1 NC_012891.1 similar to competence protein ABC transporter subunit [Streptococcus pyogenes MGAS8232]; competence protein, ABC transporter subunit 114049 8111821 SDEG_0135 Streptococcus dysgalactiae subsp. equisimilis GGS_124 competence protein, ABC transporter subunit YP_002995867.1 112958 D 486410 CDS YP_002995868.1 251781567 8111822 114051..114377 1 NC_012891.1 similar to competence protein [Streptococcus pyogenes MGAS8232]; competence protein 114377 8111822 SDEG_0136 Streptococcus dysgalactiae subsp. equisimilis GGS_124 competence protein YP_002995868.1 114051 D 486410 CDS YP_002995869.1 251781568 8111823 114337..114780 1 NC_012891.1 similar to competence protein [Streptococcus pyogenes MGAS315]; competence protein 114780 8111823 SDEG_0137 Streptococcus dysgalactiae subsp. equisimilis GGS_124 competence protein YP_002995869.1 114337 D 486410 CDS YP_002995870.1 251781569 8111824 114737..115033 1 NC_012891.1 similar to hypothetical protein SpyM3 0082 [Streptococcus pyogenes MGAS315]; hypothetical protein 115033 8111824 SDEG_0138 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002995870.1 114737 D 486410 CDS YP_002995871.1 251781570 8111825 115014..115454 1 NC_012891.1 similar to comG operon protein 6 [Streptococcus pyogenes MGAS5005]; comG operon protein 6 115454 comYD 8111825 comYD Streptococcus dysgalactiae subsp. equisimilis GGS_124 comG operon protein 6 YP_002995871.1 115014 D 486410 CDS YP_002995872.1 251781571 8111638 115432..115806 1 NC_012891.1 similar to comG operon protein 6 [Streptococcus pyogenes MGAS10750]; comG operon protein 6 115806 8111638 SDEG_0140 Streptococcus dysgalactiae subsp. equisimilis GGS_124 comG operon protein 6 YP_002995872.1 115432 D 486410 CDS YP_002995873.1 251781572 8111826 115869..116822 1 NC_012891.1 similar to adenine-specific methyltransferase [Streptococcus pyogenes MGAS2096]; adenine-specific methyltransferase 116822 8111826 SDEG_0141 Streptococcus dysgalactiae subsp. equisimilis GGS_124 adenine-specific methyltransferase YP_002995873.1 115869 D 486410 CDS YP_002995874.1 251781573 8111827 116881..118077 1 NC_012891.1 AckA utilizes acetate and can acetylate CheY which increases signal strength during flagellar rotation; utilizes magnesium and ATP; also involved in conversion of acetate to aceyl-CoA; acetate kinase 118077 ackA 8111827 ackA Streptococcus dysgalactiae subsp. equisimilis GGS_124 acetate kinase YP_002995874.1 116881 D 486410 CDS YP_002995875.1 251781574 8112298 118384..118590 1 NC_012891.1 similar to HTH-type transcriptional regulator [Streptococcus equi subsp. zooepidemicus MGCS10565]; HTH-type transcriptional regulator 118590 8112298 SDEG_0143 Streptococcus dysgalactiae subsp. equisimilis GGS_124 HTH-type transcriptional regulator YP_002995875.1 118384 D 486410 CDS YP_002995876.1 251781575 8111828 118693..119373 1 NC_012891.1 similar to membrane-bound protease CAAX family [Streptococcus equi subsp. zooepidemicus MGCS10565]; membrane-bound protease CAAX family 119373 8111828 SDEG_0144 Streptococcus dysgalactiae subsp. equisimilis GGS_124 membrane-bound protease CAAX family YP_002995876.1 118693 D 486410 CDS YP_002995877.1 251781576 8111829 119391..119828 1 NC_012891.1 similar to hypothetical protein Sez 1851 [Streptococcus equi subsp. zooepidemicus MGCS10565]; hypothetical protein 119828 8111829 SDEG_0145 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002995877.1 119391 D 486410 CDS YP_002995878.1 251781577 8111830 complement(119967..120743) 1 NC_012891.1 catalyzes the formation of L-proline from pyrroline-5-carboxylate; pyrroline-5-carboxylate reductase 120743 proC 8111830 proC Streptococcus dysgalactiae subsp. equisimilis GGS_124 pyrroline-5-carboxylate reductase YP_002995878.1 119967 R 486410 CDS YP_002995879.1 251781578 8111312 complement(120790..121857) 1 NC_012891.1 similar to glutamyl aminopeptidase [Streptococcus pyogenes MGAS10750]; glutamyl aminopeptidase 121857 pepA 8111312 pepA Streptococcus dysgalactiae subsp. equisimilis GGS_124 glutamyl aminopeptidase YP_002995879.1 120790 R 486410 CDS YP_002995880.1 251781579 8111758 complement(122032..122220) 1 NC_012891.1 similar to hypothetical protein MGAS10750 Spy0105 [Streptococcus pyogenes MGAS10750]; hypothetical protein 122220 8111758 SDEG_0148 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002995880.1 122032 R 486410 CDS YP_002995881.1 251781580 8111831 122407..122700 1 NC_012891.1 similar to hypothetical membrane associated protein [Streptococcus pyogenes MGAS5005]; hypothetical protein 122700 8111831 SDEG_0149 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002995881.1 122407 D 486410 CDS YP_002995882.1 251781581 8111832 122697..123014 1 NC_012891.1 similar to thioredoxin [Streptococcus pyogenes MGAS8232]; thioredoxin 123014 trxA 8111832 trxA Streptococcus dysgalactiae subsp. equisimilis GGS_124 thioredoxin YP_002995882.1 122697 D 486410 CDS YP_002995883.1 251781582 8111932 123032..123658 1 NC_012891.1 similar to tRNA binding domain protein [Streptococcus pyogenes MGAS10394]; tRNA binding domain-containing protein 123658 8111932 SDEG_0151 Streptococcus dysgalactiae subsp. equisimilis GGS_124 tRNA binding domain-containing protein YP_002995883.1 123032 D 486410 CDS YP_002995884.1 251781583 8111833 123810..124205 1 NC_012891.1 binds to single stranded DNA and may facilitate the binding and interaction of other proteins to DNA; single-stranded DNA-binding protein 124205 8111833 SDEG_0152 Streptococcus dysgalactiae subsp. equisimilis GGS_124 single-stranded DNA-binding protein YP_002995884.1 123810 D 486410 CDS YP_002995885.1 251781584 8111834 complement(124465..125154) 1 NC_012891.1 similar to deoxyadenosine kinase [Streptococcus pyogenes MGAS10394]; deoxyadenosine kinase 125154 8111834 SDEG_0153 Streptococcus dysgalactiae subsp. equisimilis GGS_124 deoxyadenosine kinase YP_002995885.1 124465 R 486410 CDS YP_002995886.1 251781585 8111835 complement(125126..126190) 1 NC_012891.1 similar to tRNA-dihydrouridine synthase [Streptococcus pyogenes MGAS2096]; tRNA-dihydrouridine synthase 126190 8111835 SDEG_0154 Streptococcus dysgalactiae subsp. equisimilis GGS_124 tRNA-dihydrouridine synthase YP_002995886.1 125126 R 486410 CDS YP_002995887.1 251781586 8111836 complement(126090..126962) 1 NC_012891.1 becomes active under oxidative stress; four conserved cysteines bind a zinc atom when they are in the reduced state and the enzyme is inactive; oxidative stress results in oxidized cysteines, release of zinc, and binding of Hsp33 to aggregation-prone proteins; forms dimers and higher order oligomers; Hsp33-like chaperonin 126962 hslO 8111836 hslO Streptococcus dysgalactiae subsp. equisimilis GGS_124 Hsp33-like chaperonin YP_002995887.1 126090 R 486410 CDS YP_002995888.1 251781587 8112038 complement(127109..128701) 1 NC_012891.1 similar to transcriptional regulator RofA [Streptococcus pyogenes MGAS10750]; transcriptional regulator 128701 rofA 8112038 rofA Streptococcus dysgalactiae subsp. equisimilis GGS_124 transcriptional regulator YP_002995888.1 127109 R 486410 CDS YP_002995889.1 251781588 8111053 128883..130817 1 NC_012891.1 similar to fimbrial subunit protein FszF [Streptococcus equi subsp. zooepidemicus MGCS10565]; fimbrial subunit protein 130817 fszF 8111053 fszF Streptococcus dysgalactiae subsp. equisimilis GGS_124 fimbrial subunit protein YP_002995889.1 128883 D 486410 CDS YP_002995890.1 251781589 8111913 130900..131844 1 NC_012891.1 similar to T-antigen-like fimbrial structural subunit protein FszE [Streptococcus equi subsp. zooepidemicus MGCS10565]; T-antigen-like fimbrial structural subunit protein 131844 fszE 8111913 fszE Streptococcus dysgalactiae subsp. equisimilis GGS_124 T-antigen-like fimbrial structural subunit protein YP_002995890.1 130900 D 486410 CDS YP_002995891.1 251781590 8111912 131849..132727 1 NC_012891.1 similar to sortase [Streptococcus pyogenes MGAS10270]; sortase 132727 8111912 SDEG_0159 Streptococcus dysgalactiae subsp. equisimilis GGS_124 sortase YP_002995891.1 131849 D 486410 CDS YP_002995892.1 251781591 8111837 132711..133568 1 NC_012891.1 similar to sortase [Streptococcus pyogenes MGAS10270]; sortase 133568 8111837 SDEG_0160 Streptococcus dysgalactiae subsp. equisimilis GGS_124 sortase YP_002995892.1 132711 D 486410 CDS YP_002995893.1 251781592 8111838 133629..138743 1 NC_012891.1 similar to fibronectin-binding protein [Streptococcus pyogenes MGAS10270]; fibronectin-binding protein 138743 8111838 SDEG_0161 Streptococcus dysgalactiae subsp. equisimilis GGS_124 fibronectin-binding protein YP_002995893.1 133629 D 486410 CDS YP_002995894.1 251781593 8111839 complement(138808..139485) 1 NC_012891.1 similar to DNA-binding protein [Streptococcus pyogenes MGAS10394]; DNA-binding protein 139485 8111839 SDEG_0162 Streptococcus dysgalactiae subsp. equisimilis GGS_124 DNA-binding protein YP_002995894.1 138808 R 486410 CDS YP_002995895.1 251781594 8111435 139658..140023 1 NC_012891.1 similar to translation initiation inhibitor [Streptococcus pyogenes MGAS10394]; translation initiation inhibitor 140023 8111435 SDEG_0163 Streptococcus dysgalactiae subsp. equisimilis GGS_124 translation initiation inhibitor YP_002995895.1 139658 D 486410 CDS YP_002995896.1 251781595 8111436 140049..141080 1 NC_012891.1 similar to hypothetical protein SpyM50119 [Streptococcus pyogenes str. Manfredo]; hypothetical protein 141080 8111436 SDEG_0164 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002995896.1 140049 D 486410 CDS YP_002995897.1 251781596 8111437 complement(141382..142644) 1 NC_012891.1 similar to tellurite resistance protein [Streptococcus pyogenes MGAS10394]; tellurite resistance protein 142644 8111437 SDEG_0165 Streptococcus dysgalactiae subsp. equisimilis GGS_124 tellurite resistance protein YP_002995897.1 141382 R 486410 CDS YP_002995898.1 251781597 8111438 complement(142657..143535) 1 NC_012891.1 similar to hypothetical membrane associated protein [Streptococcus pyogenes MGAS10394]; hypothetical protein 143535 8111438 SDEG_0166 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002995898.1 142657 R 486410 CDS YP_002995899.1 251781598 8111439 143964..145256 1 NC_012891.1 catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis; adenylosuccinate synthetase 145256 purA 8111439 purA Streptococcus dysgalactiae subsp. equisimilis GGS_124 adenylosuccinate synthetase YP_002995899.1 143964 D 486410 CDS YP_002995900.1 251781599 8111330 145582..146625 1 NC_012891.1 similar to nucleoside-binding protein [Streptococcus pyogenes MGAS5005]; nucleoside-binding protein 146625 8111330 SDEG_0168 Streptococcus dysgalactiae subsp. equisimilis GGS_124 nucleoside-binding protein YP_002995900.1 145582 D 486410 CDS YP_002995901.1 251781600 8111440 complement(146829..147602) 1 NC_012891.1 similar to pyruvate formate-lyase activating enzyme [Streptococcus pyogenes MGAS10394]; pyruvate formate-lyase activating enzyme 147602 8111440 SDEG_0169 Streptococcus dysgalactiae subsp. equisimilis GGS_124 pyruvate formate-lyase activating enzyme YP_002995901.1 146829 R 486410 CDS YP_002995902.1 251781601 8111441 147725..148474 1 NC_012891.1 similar to DeoR family transcriptional regulator [Streptococcus pyogenes MGAS10394]; DeoR family transcriptional regulator 148474 8111441 SDEG_0170 Streptococcus dysgalactiae subsp. equisimilis GGS_124 DeoR family transcriptional regulator YP_002995902.1 147725 D 486410 CDS YP_002995903.1 251781602 8111442 148490..149470 1 NC_012891.1 similar to sorbitol operon regulator [Streptococcus pyogenes MGAS10394]; sorbitol operon regulator 149470 8111442 SDEG_0171 Streptococcus dysgalactiae subsp. equisimilis GGS_124 sorbitol operon regulator YP_002995903.1 148490 D 486410 CDS YP_002995904.1 251781603 8111443 149750..150070 1 NC_012891.1 similar to PTS system, cellobiose-specific IIA component [Streptococcus pyogenes MGAS5005]; PTS system cellobiose-specific transporter subunit IIA 150070 8111443 SDEG_0172 Streptococcus dysgalactiae subsp. equisimilis GGS_124 PTS system cellobiose-specific transporter subunit IIA YP_002995904.1 149750 D 486410 CDS YP_002995905.1 251781604 8111444 150098..150406 1 NC_012891.1 similar to PTS system, cellobiose-specific IIB component [Streptococcus pyogenes MGAS10750]; PTS system cellobiose-specific transporter subunit IIB 150406 8111444 SDEG_0173 Streptococcus dysgalactiae subsp. equisimilis GGS_124 PTS system cellobiose-specific transporter subunit IIB YP_002995905.1 150098 D 486410 CDS YP_002995906.1 251781605 8111445 150416..151720 1 NC_012891.1 similar to PTS system, cellobiose-specific IIB component [Streptococcus pyogenes MGAS10750]; PTS system cellobiose-specific transporter subunit IIC 151720 8111445 SDEG_0174 Streptococcus dysgalactiae subsp. equisimilis GGS_124 PTS system cellobiose-specific transporter subunit IIC YP_002995906.1 150416 D 486410 CDS YP_002995907.1 251781606 8111446 151931..154348 1 NC_012891.1 similar to formate acetyltransferase [Streptococcus pyogenes MGAS10394]; formate acetyltransferase 154348 8111446 SDEG_0175 Streptococcus dysgalactiae subsp. equisimilis GGS_124 formate acetyltransferase YP_002995907.1 151931 D 486410 CDS YP_002995908.1 251781607 8111447 154361..155029 1 NC_012891.1 similar to transaldolase from Escherichia coli; many organisms have multiple copies; fructose-6-phosphate aldolase 155029 mipB 8111447 mipB Streptococcus dysgalactiae subsp. equisimilis GGS_124 fructose-6-phosphate aldolase YP_002995908.1 154361 D 486410 CDS YP_002995909.1 251781608 8110939 155071..156159 1 NC_012891.1 forms dimers and octamers; involved in conversion of glycerol to dihydroxy-acetone; glycerol dehydrogenase 156159 gldA 8110939 gldA Streptococcus dysgalactiae subsp. equisimilis GGS_124 glycerol dehydrogenase YP_002995909.1 155071 D 486410 CDS YP_002995910.1 251781609 8111995 156347..156658 1 NC_012891.1 similar to hypothetical protein SsuiDRAFT 0887 [Streptococcus suis 89/1591]; hypothetical protein 156658 8111995 SDEG_0178 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002995910.1 156347 D 486410 CDS YP_002995911.1 251781610 8111448 complement(156731..157240) 1 NC_012891.1 similar to low temperature requirement C protein [Streptococcus pyogenes MGAS8232]; low temperature requirement C protein 157240 8111448 SDEG_0179 Streptococcus dysgalactiae subsp. equisimilis GGS_124 low temperature requirement C protein YP_002995911.1 156731 R 486410 CDS YP_002995912.1 251781611 8111449 157414..157965 1 NC_012891.1 no hit; hypothetical protein 157965 8111449 SDEG_0180 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002995912.1 157414 D 486410 CDS YP_002995913.1 251781612 8111450 158072..159097 1 NC_012891.1 similar to MccC family protein [Streptococcus pneumoniae D39]; MccC family protein 159097 8111450 SDEG_0181 Streptococcus dysgalactiae subsp. equisimilis GGS_124 MccC family protein YP_002995913.1 158072 D 486410 CDS YP_002995914.1 251781613 8111451 complement(159237..160535) 1 NC_012891.1 similar to hypothetical protein PsycPRwf 0104 [Psychrobacter sp. PRwf-1]; hypothetical protein 160535 8111451 SDEG_0182 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002995914.1 159237 R 486410 CDS YP_002995915.1 251781614 8111452 160732..161220 1 NC_012891.1 similar to YbaK / prolyl-tRNA synthetases associated domain; YbaK/prolyl-tRNA synthetases associated domain 161220 8111452 SDEG_0183 Streptococcus dysgalactiae subsp. equisimilis GGS_124 YbaK/prolyl-tRNA synthetases associated domain YP_002995915.1 160732 D 486410 CDS YP_002995916.1 251781615 8111453 complement(161359..161628) 1 NC_012891.1 similar to predicted transcriptional regulator [Streptococcus suis 98HAH33]; transcriptional regulator 161628 8111453 SDEG_0184 Streptococcus dysgalactiae subsp. equisimilis GGS_124 transcriptional regulator YP_002995916.1 161359 R 486410 CDS YP_002995917.1 251781616 8111454 complement(162212..163639) 1 NC_012891.1 similar to hypothetical protein SAG0685 [Streptococcus agalactiae 2603V/R]; hypothetical protein 163639 8111454 SDEG_0185 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002995917.1 162212 R 486410 CDS YP_002995918.1 251781617 8111455 complement(163782..165293) 1 NC_012891.1 similar to ATPase components of ABC transporters with duplicated ATPase domains, multidrug transport system [Streptococcus sanguinis SK36]; ATPase components of ABC transporters 165293 8111455 SDEG_0186 Streptococcus dysgalactiae subsp. equisimilis GGS_124 ATPase components of ABC transporters YP_002995918.1 163782 R 486410 CDS YP_002995919.1 251781618 8111456 complement(165566..166186) 1 NC_012891.1 similar to cyclic nucleotide-binding domain protein [Lactococcus lactis subsp. cremoris MG1363]; cyclic nucleotide-binding domain-containing protein 166186 8111456 SDEG_0187 Streptococcus dysgalactiae subsp. equisimilis GGS_124 cyclic nucleotide-binding domain-containing protein YP_002995919.1 165566 R 486410 CDS YP_002995920.1 251781619 8111457 166263..166859 1 NC_012891.1 similar to hypothetical protein llmg 1236 [Lactococcus lactis subsp. cremoris MG1363]; hypothetical protein 166859 8111457 SDEG_0188 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002995920.1 166263 D 486410 CDS YP_002995921.1 251781620 8111458 166869..167519 1 NC_012891.1 similar to nucleotide-binding protein implicated in inhibition of septum formation [Streptococcus suis 98HAH33]; nucleotide-binding protein 167519 8111458 SDEG_0189 Streptococcus dysgalactiae subsp. equisimilis GGS_124 nucleotide-binding protein YP_002995921.1 166869 D 486410 CDS YP_002995922.1 251781621 8111459 complement(167648..168001) 1 NC_012891.1 no hit; hypothetical protein 168001 8111459 SDEG_0190 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002995922.1 167648 R 486410 CDS YP_002995923.1 251781622 8111460 168818..169204 1 NC_012891.1 similar to phosphoglycerate mutase family protein [Streptococcus equi subsp. zooepidemicus MGCS10565]; phosphoglycerate mutase 169204 8111460 SDEG_0191 Streptococcus dysgalactiae subsp. equisimilis GGS_124 phosphoglycerate mutase YP_002995923.1 168818 D 486410 CDS YP_002995924.1 251781623 8111461 complement(169256..169762) 1 NC_012891.1 similar to topology modulation protein [Streptococcus pyogenes MGAS6180]; topology modulation protein 169762 flaR 8111461 flaR Streptococcus dysgalactiae subsp. equisimilis GGS_124 topology modulation protein YP_002995924.1 169256 R 486410 CDS YP_002995925.1 251781624 8111898 complement(169817..170299) 1 NC_012891.1 similar to acetyltransferase [Streptococcus pyogenes MGAS10394]; acetyltransferase 170299 8111898 SDEG_0193 Streptococcus dysgalactiae subsp. equisimilis GGS_124 acetyltransferase YP_002995925.1 169817 R 486410 CDS YP_002995926.1 251781625 8111462 170671..171699 1 NC_012891.1 similar to transposase [Streptococcus pyogenes MGAS10270]; transposase 171699 8111462 SDEG_0194 Streptococcus dysgalactiae subsp. equisimilis GGS_124 transposase YP_002995926.1 170671 D 486410 CDS YP_002995927.1 251781626 8111463 171832..173145 1 NC_012891.1 similar to transcriptional regulator [Streptococcus equi subsp. zooepidemicus MGCS10565]; transcriptional regulator 173145 8111463 SDEG_0195 Streptococcus dysgalactiae subsp. equisimilis GGS_124 transcriptional regulator YP_002995927.1 171832 D 486410 CDS YP_002995928.1 251781627 8111464 173214..174878 1 NC_012891.1 similar to bacteriocin ABC-type exporter ATP binding/permease protein [Streptococcus sanguinis SK36]; bacteriocin ABC-type exporter, ATP binding/permease 174878 8111464 SDEG_0196 Streptococcus dysgalactiae subsp. equisimilis GGS_124 bacteriocin ABC-type exporter, ATP binding/permease YP_002995928.1 173214 D 486410 CDS YP_002995929.1 251781628 8111465 174898..175101 1 NC_012891.1 similar to hypothetical protein M28 Spy1333 [Streptococcus pyogenes MGAS6180]; hypothetical protein 175101 8111465 SDEG_0197 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002995929.1 174898 D 486410 CDS YP_002995930.1 251781629 8111466 175341..176195 1 NC_012891.1 similar to streptomycin resistance protein [Streptococcus agalactiae 2603V/R]; streptomycin resistance protein 176195 8111466 SDEG_0198 Streptococcus dysgalactiae subsp. equisimilis GGS_124 streptomycin resistance protein YP_002995930.1 175341 D 486410 CDS YP_002995931.1 251781630 8111467 176218..176778 1 NC_012891.1 similar to phosphoglycerate mutase family protein [Streptococcus equi subsp. zooepidemicus MGCS10565]; phosphoglycerate mutase 176778 8111467 SDEG_0199 Streptococcus dysgalactiae subsp. equisimilis GGS_124 phosphoglycerate mutase YP_002995931.1 176218 D 486410 CDS YP_002995932.1 251781631 8111468 177881..178147 1 NC_012891.1 similar to transposase [Streptococcus pyogenes MGAS2096]; transposase 178147 8111468 SDEG_0200 Streptococcus dysgalactiae subsp. equisimilis GGS_124 transposase YP_002995932.1 177881 D 486410 CDS YP_002995933.1 251781632 8111469 178226..178744 1 NC_012891.1 similar to transposase [Streptococcus pyogenes MGAS2096]; transposase 178744 8111469 SDEG_0201 Streptococcus dysgalactiae subsp. equisimilis GGS_124 transposase YP_002995933.1 178226 D 486410 CDS YP_002995934.1 251781633 8111470 178798..179526 1 NC_012891.1 similar to hypothetical protein gbs1981 [Streptococcus agalactiae NEM316]; hypothetical protein 179526 8111470 SDEG_0202 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002995934.1 178798 D 486410 CDS YP_002995935.1 251781634 8111471 179957..180193 1 NC_012891.1 similar to hypothetical protein M28 Spy1332 [Streptococcus pyogenes MGAS6180]; hypothetical protein 180193 8111471 SDEG_0203 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002995935.1 179957 D 486410 CDS YP_002995936.1 251781635 8111472 180639..181442 1 NC_012891.1 similar to hypothetical protein M28 Spy1308 [Streptococcus pyogenes MGAS6180]; hypothetical protein 181442 8111472 SDEG_0204 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002995936.1 180639 D 486410 CDS YP_002995937.1 251781636 8111473 complement(181483..182262) 1 NC_012891.1 similar to ISSdy1 transposase OrfB [Streptococcus agalactiae 2603V/R]; ISSdy1, transposase OrfB 182262 8111473 SDEG_0205 Streptococcus dysgalactiae subsp. equisimilis GGS_124 ISSdy1, transposase OrfB YP_002995937.1 181483 R 486410 CDS YP_002995938.1 251781637 8111474 complement(182298..182588) 1 NC_012891.1 similar to ISSdy1 transposase OrfA [Streptococcus agalactiae 515]; ISSdy1, transposase OrfA 182588 8111474 SDEG_0206 Streptococcus dysgalactiae subsp. equisimilis GGS_124 ISSdy1, transposase OrfA YP_002995938.1 182298 R 486410 CDS YP_002995939.1 251781638 8111475 complement(182811..184145) 1 NC_012891.1 similar to protein kinase, [Streptococcus pneumoniae TIGR4]; protein kinase 184145 8111475 SDEG_0207 Streptococcus dysgalactiae subsp. equisimilis GGS_124 protein kinase YP_002995939.1 182811 R 486410 CDS YP_002995940.1 251781639 8111476 complement(184142..184435) 1 NC_012891.1 similar to hypothetical protein SP 1060 [Streptococcus pneumoniae TIGR4]; hypothetical protein 184435 8111476 SDEG_0208 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002995940.1 184142 R 486410 CDS YP_002995941.1 251781640 8111477 complement(184498..184737) 1 NC_012891.1 similar to hypothetical protein SP 1059 [Streptococcus pneumoniae TIGR4]; hypothetical protein 184737 8111477 SDEG_0209 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002995941.1 184498 R 486410 CDS YP_002995942.1 251781641 8111478 184881..185789 1 NC_012891.1 similar to ABC transporter ATP-binding protein [Streptococcus pneumoniae TIGR4]; ABC transporter ATP-binding protein 185789 8111478 SDEG_0210 Streptococcus dysgalactiae subsp. equisimilis GGS_124 ABC transporter ATP-binding protein YP_002995942.1 184881 D 486410 CDS YP_002995943.1 251781642 8111479 185816..186616 1 NC_012891.1 similar to ABC-2 transporter permease protein [Streptococcus pneumoniae TIGR4]; ABC transporter permease 186616 8111479 SDEG_0211 Streptococcus dysgalactiae subsp. equisimilis GGS_124 ABC transporter permease YP_002995943.1 185816 D 486410 CDS YP_002995944.1 251781643 8111480 186743..187378 1 NC_012891.1 similar to transposase IS204/IS1001/IS1096/IS1165 [Streptococcus suis 89/1591]; transposase 187378 8111480 SDEG_0212 Streptococcus dysgalactiae subsp. equisimilis GGS_124 transposase YP_002995944.1 186743 D 486410 CDS YP_002995946.1 251781644 8111482 complement(187820..189109) 1 NC_012891.1 similar to recombination factor protein RarA [Streptococcus thermophilus LMG 18311]; recombination factor protein RarA 189109 cshA 8111482 cshA Streptococcus dysgalactiae subsp. equisimilis GGS_124 recombination factor protein RarA YP_002995946.1 187820 R 486410 CDS YP_002995947.1 251781645 8111650 complement(189142..189708) 1 NC_012891.1 TrpG; with TrpE catalyzes the formation of anthranilate and glutamate from chorismate and glutamine; TrpG provides the glutamine amidotransferase activity; anthranilate synthase component II 189708 8111650 SDEG_0216 Streptococcus dysgalactiae subsp. equisimilis GGS_124 anthranilate synthase component II YP_002995947.1 189142 R 486410 CDS YP_002995948.1 251781646 8111483 complement(189741..191504) 1 NC_012891.1 similar to para-aminobenzoate synthetase component I/4-amino-4-deoxychorismate lyase [Streptococcus pyogenes MGAS5005]; para-aminobenzoate synthetase componentI/4-amino-4-deoxychorismate lyase 191504 8111483 SDEG_0217 Streptococcus dysgalactiae subsp. equisimilis GGS_124 para-aminobenzoate synthetase componentI/4-amino-4-deoxychorismate lyase YP_002995948.1 189741 R 486410 CDS YP_002995949.1 251781647 8111484 191698..192168 1 NC_012891.1 similar to hypothetical protein MGAS2096 Spy1717 [Streptococcus pyogenes MGAS2096]; hypothetical protein 192168 8111484 SDEG_0218 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002995949.1 191698 D 486410 CDS YP_002995950.1 251781648 8111485 192239..193192 1 NC_012891.1 methylates ribosomal protein L11 at multiple amino acid positions; mutations of these genes in Escherichia coli or Thermus thermophilus has no apparent phenotype; 50S ribosomal protein L11 methyltransferase 193192 prmA 8111485 prmA Streptococcus dysgalactiae subsp. equisimilis GGS_124 50S ribosomal protein L11 methyltransferase YP_002995950.1 192239 D 486410 CDS YP_002995951.1 251781649 8111486 193192..193950 1 NC_012891.1 in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA; cells lacking this function can grow, but are outcompeted by wild-type; SAM-dependent m(3)U1498 methyltransferase; 16S ribosomal RNA methyltransferase RsmE 193950 8111486 SDEG_0220 Streptococcus dysgalactiae subsp. equisimilis GGS_124 16S ribosomal RNA methyltransferase RsmE YP_002995951.1 193192 D 486410 CDS YP_002995952.1 251781650 8111487 194102..195124 1 NC_012891.1 similar to HTH-type transcriptional regulator MalR-like [Streptococcus equi subsp. zooepidemicus MGCS10565]; HTH-type transcriptional regulator 195124 8111487 SDEG_0221 Streptococcus dysgalactiae subsp. equisimilis GGS_124 HTH-type transcriptional regulator YP_002995952.1 194102 D 486410 CDS YP_002995953.1 251781651 8111488 195394..197580 1 NC_012891.1 similar to PTS system glucose-specific IIABC component [Streptococcus pyogenes MGAS10394]; PTS system glucose-specific transporter subunit IIABC 197580 8111488 SDEG_0222 Streptococcus dysgalactiae subsp. equisimilis GGS_124 PTS system glucose-specific transporter subunit IIABC YP_002995953.1 195394 D 486410 CDS YP_002995954.1 251781652 8111489 197659..198483 1 NC_012891.1 similar to RgfB protein [Streptococcus pyogenes MGAS315]; RgfB protein 198483 rgfB 8111489 rgfB Streptococcus dysgalactiae subsp. equisimilis GGS_124 RgfB protein YP_002995954.1 197659 D 486410 CDS YP_002995955.1 251781653 8111045 complement(198492..199004) 1 NC_012891.1 similar to hypothetical protein SAG1944 [Streptococcus agalactiae 2603V/R]; hypothetical protein 199004 8111045 SDEG_0224 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002995955.1 198492 R 486410 CDS YP_002995956.1 251781654 8111490 complement(199028..200128) 1 NC_012891.1 similar to glucanase; deblocking aminopeptidase [Bacillus cereus E33L]; glucanase; deblocking aminopeptidase 200128 8111490 SDEG_0225 Streptococcus dysgalactiae subsp. equisimilis GGS_124 glucanase; deblocking aminopeptidase YP_002995956.1 199028 R 486410 CDS YP_002995957.1 251781655 8111491 complement(200136..200687) 1 NC_012891.1 similar to hypothetical protein gbs0573 [Streptococcus agalactiae NEM316]; hypothetical protein 200687 8111491 SDEG_0226 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002995957.1 200136 R 486410 CDS YP_002995958.1 251781656 8111492 complement(200691..201671) 1 NC_012891.1 similar to inosine-uridine preferring nucleoside hydrolase [Streptococcus agalactiae 2603V/R]; inosine-uridine preferring nucleoside hydrolase 201671 8111492 SDEG_0227 Streptococcus dysgalactiae subsp. equisimilis GGS_124 inosine-uridine preferring nucleoside hydrolase YP_002995958.1 200691 R 486410 CDS YP_002995959.1 251781657 8111493 complement(201952..202419) 1 NC_012891.1 has a stimulatory effect on the ribonucleotide reductase activity of NrdH with NrdEF; flavoprotein NrdI 202419 nrdI 8111493 nrdI Streptococcus dysgalactiae subsp. equisimilis GGS_124 flavoprotein NrdI YP_002995959.1 201952 R 486410 CDS YP_002995960.1 251781658 8111721 202906..204447 1 NC_012891.1 similar to trans-acting positive regulator [Streptococcus pyogenes MGAS10394]; trans-acting positive regulator 204447 mgg 8111721 mgg Streptococcus dysgalactiae subsp. equisimilis GGS_124 trans-acting positive regulator YP_002995960.1 202906 D 486410 CDS YP_002995961.1 251781659 8110937 204718..206343 1 NC_012891.1 similar to M protein; antiphagocytic M protein 206343 stg480.0 8110937 stg480.0 Streptococcus dysgalactiae subsp. equisimilis GGS_124 antiphagocytic M protein YP_002995961.1 204718 D 486410 CDS YP_002995962.1 251781660 8110506 206884..209103 1 NC_012891.1 similar to GTP pyrophosphokinase [Streptococcus pyogenes MGAS10394]; GTP pyrophosphokinase 209103 8110506 SDEG_0231 Streptococcus dysgalactiae subsp. equisimilis GGS_124 GTP pyrophosphokinase YP_002995962.1 206884 D 486410 CDS YP_002995963.1 251781661 8111494 209117..209560 1 NC_012891.1 hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr); possible defense mechanism against a harmful effect of D-tyrosine; D-tyrosyl-tRNA(Tyr) deacylase 209560 8111494 SDEG_0232 Streptococcus dysgalactiae subsp. equisimilis GGS_124 D-tyrosyl-tRNA(Tyr) deacylase YP_002995963.1 209117 D 486410 CDS YP_002995964.1 251781662 8111495 complement(209658..210980) 1 NC_012891.1 similar to streptokinase [Streptococcus pyogenes MGAS10394]; streptokinase 210980 8111495 SDEG_0233 Streptococcus dysgalactiae subsp. equisimilis GGS_124 streptokinase YP_002995964.1 209658 R 486410 CDS YP_002995965.1 251781663 8111496 211267..212157 1 NC_012891.1 similar to leucine rich protein [Streptococcus pyogenes MGAS10394]; hypothetical protein 212157 8111496 SDEG_0234 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002995965.1 211267 D 486410 CDS YP_002995966.1 251781664 8111497 212455..213588 1 NC_012891.1 similar to multiple sugar transport ATP-binding protein [Streptococcus pyogenes MGAS10394]; multiple sugar transport ATP-binding protein 213588 8111497 SDEG_0235 Streptococcus dysgalactiae subsp. equisimilis GGS_124 multiple sugar transport ATP-binding protein YP_002995966.1 212455 D 486410 CDS YP_002995967.1 251781665 8111498 213664..215283 1 NC_012891.1 similar to glucan 1,6-alpha-glucosidase [Streptococcus pyogenes MGAS10394]; glucan 1,6-alpha-glucosidase 215283 8111498 SDEG_0236 Streptococcus dysgalactiae subsp. equisimilis GGS_124 glucan 1,6-alpha-glucosidase YP_002995967.1 213664 D 486410 CDS YP_002995968.1 251781666 8111499 215449..219072 1 NC_012891.1 similar to pullulanase [Streptococcus pyogenes MGAS10394]; pullulanase 219072 8111499 SDEG_0237 Streptococcus dysgalactiae subsp. equisimilis GGS_124 pullulanase YP_002995968.1 215449 D 486410 CDS YP_002995969.1 251781667 8111500 complement(219225..219515) 1 NC_012891.1 similar to hypothetical protein SPCG 1675 [Streptococcus pneumoniae CGSP14]; hypothetical protein 219515 8111500 SDEG_0238 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002995969.1 219225 R 486410 CDS YP_002995970.1 251781668 8111501 219671..220021 1 NC_012891.1 similar to thioredoxin [Streptococcus pyogenes MGAS2096]; thioredoxin 220021 8111501 SDEG_0239 Streptococcus dysgalactiae subsp. equisimilis GGS_124 thioredoxin YP_002995970.1 219671 D 486410 CDS YP_002995971.1 251781669 8111502 220128..220487 1 NC_012891.1 member of preprotein translocase; forms a heterotrimer with SecD and SecF; links the SecD/SecF/YajC/YidC complex with the SecY/SecE/SecG complex; preprotein translocase subunit YajC 220487 yajC 8111502 yajC Streptococcus dysgalactiae subsp. equisimilis GGS_124 preprotein translocase subunit YajC YP_002995971.1 220128 D 486410 CDS YP_002995972.1 251781670 8111958 220715..221464 1 NC_012891.1 catalyzes the formation of undecaprenyl pyrophosphate from isopentenyl pyrophosphate; UDP pyrophosphate synthase 221464 8111958 SDEG_0241 Streptococcus dysgalactiae subsp. equisimilis GGS_124 UDP pyrophosphate synthase YP_002995972.1 220715 D 486410 CDS YP_002995973.1 251781671 8111503 221477..222271 1 NC_012891.1 similar to phosphatidate cytidylyltransferase [Streptococcus pyogenes MGAS10394]; phosphatidate cytidylyltransferase 222271 8111503 SDEG_0242 Streptococcus dysgalactiae subsp. equisimilis GGS_124 phosphatidate cytidylyltransferase YP_002995973.1 221477 D 486410 CDS YP_002995974.1 251781672 8111504 222369..223082 1 NC_012891.1 similar to pheromone-processing membrane metalloprotease [Streptococcus pyogenes MGAS10394]; pheromone-processing membrane metalloprotease 223082 8111504 SDEG_0243 Streptococcus dysgalactiae subsp. equisimilis GGS_124 pheromone-processing membrane metalloprotease YP_002995974.1 222369 D 486410 CDS YP_002995975.1 251781673 8111505 222956..223627 1 NC_012891.1 similar to pheromone-processing membrane metalloprotease [Streptococcus pyogenes MGAS10394]; pheromone-processing membrane metalloprotease 223627 8111505 SDEG_0244 Streptococcus dysgalactiae subsp. equisimilis GGS_124 pheromone-processing membrane metalloprotease YP_002995975.1 222956 D 486410 CDS YP_002995976.1 251781674 8111506 223818..225674 1 NC_012891.1 catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro); prolyl-tRNA synthetase 225674 8111506 SDEG_0245 Streptococcus dysgalactiae subsp. equisimilis GGS_124 prolyl-tRNA synthetase YP_002995976.1 223818 D 486410 CDS YP_002995977.1 251781675 8111507 225727..226284 1 NC_012891.1 similar to hypothetical protein ProS [Streptococcus equi subsp. zooepidemicus MGCS10565]; hypothetical protein 226284 8111507 SDEG_0246 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002995977.1 225727 D 486410 CDS YP_002995978.1 251781676 8111508 226401..230798 1 NC_012891.1 catalyzes DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time; required for leading strand synthesis; PolC exhibits 3' to 5' exonuclease activity; DNA polymerase III PolC 230798 polC 8111508 polC Streptococcus dysgalactiae subsp. equisimilis GGS_124 DNA polymerase III PolC YP_002995978.1 226401 D 486410 CDS YP_002995979.1 251781677 8111509 230964..231392 1 NC_012891.1 similar to MarR family transcriptional regulator [Streptococcus pyogenes M1 GAS]; MarR family transcriptional regulator 231392 8111509 SDEG_0248 Streptococcus dysgalactiae subsp. equisimilis GGS_124 MarR family transcriptional regulator YP_002995979.1 230964 D 486410 CDS YP_002995980.1 251781678 8111510 231478..232029 1 NC_012891.1 similar to NADPH-dependent FMN reductase [Streptococcus sanguinis SK36]; NADPH-dependent FMN reductase 232029 8111510 SDEG_0249 Streptococcus dysgalactiae subsp. equisimilis GGS_124 NADPH-dependent FMN reductase YP_002995980.1 231478 D 486410 CDS YP_002995981.1 251781679 8111511 complement(232097..232711) 1 NC_012891.1 cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+); peptide deformylase 232711 def 8111511 def Streptococcus dysgalactiae subsp. equisimilis GGS_124 peptide deformylase YP_002995981.1 232097 R 486410 CDS YP_002995982.1 251781680 8111666 complement(233011..233676) 1 NC_012891.1 similar to Crp-like transcriptional regulator [Streptococcus thermophilus LMD-9]; Crp-like transcriptional regulator 233676 8111666 SDEG_0251 Streptococcus dysgalactiae subsp. equisimilis GGS_124 Crp-like transcriptional regulator YP_002995982.1 233011 R 486410 CDS YP_002995983.1 251781681 8111512 233764..234948 1 NC_012891.1 similar to hypothetical protein SMU.145 [Streptococcus mutans UA159]; hypothetical protein 234948 8111512 SDEG_0252 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002995983.1 233764 D 486410 CDS YP_002995984.1 251781682 8111513 235096..235365 1 NC_012891.1 primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence; 30S ribosomal protein S15 235365 rpsO 8111513 rpsO Streptococcus dysgalactiae subsp. equisimilis GGS_124 30S ribosomal protein S15 YP_002995984.1 235096 D 486410 CDS YP_002995985.1 251781683 8111107 235349..235480 1 NC_012891.1 similar to hypothetical protein M6 Spy1673 [Streptococcus pyogenes MGAS10394]; hypothetical protein 235480 8111107 SDEG_0254 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002995985.1 235349 D 486410 CDS YP_002995986.1 251781684 8111514 235616..237778 1 NC_012891.1 similar to PTS system mannitol (Cryptic)-specific IIA component [Streptococcus pyogenes MGAS10394]; PTS system mannitol (cryptic)-specific transporter subunit IIA 237778 8111514 SDEG_0255 Streptococcus dysgalactiae subsp. equisimilis GGS_124 PTS system mannitol (cryptic)-specific transporter subunit IIA YP_002995986.1 235616 D 486410 CDS YP_002995987.1 251781685 8111515 237750..238055 1 NC_012891.1 similar to PTS system IIB component [Streptococcus pyogenes MGAS6180]; PTS system transporter subunit IIB 238055 8111515 SDEG_0256 Streptococcus dysgalactiae subsp. equisimilis GGS_124 PTS system transporter subunit IIB YP_002995987.1 237750 D 486410 CDS YP_002995988.1 251781686 8111354 238082..239461 1 NC_012891.1 membrane component; functions with enzymes IIB (sgaB; ulaB) and IIA (sgaA; ulaC) enzyme I and HPr for anaerobic utilization and uptake of L-ascorbate; sgaTBA are regulated by yifQ as well as Crp and Fnr; PTS system ascorbate-specific transporter subunit IIC 239461 ulaA 8111354 ulaA Streptococcus dysgalactiae subsp. equisimilis GGS_124 PTS system ascorbate-specific transporter subunit IIC YP_002995988.1 238082 D 486410 CDS YP_002995989.1 251781687 8111939 239471..240202 1 NC_012891.1 similar to novel fructose-6-phosphate aldolase from Escherichia coli; enzyme from Methanocaldococcus janaschii shows transaldolase activity; translaldolase 240202 8111939 SDEG_0258 Streptococcus dysgalactiae subsp. equisimilis GGS_124 translaldolase YP_002995989.1 239471 D 486410 CDS YP_002995990.1 251781688 8111355 240482..242626 1 NC_012891.1 similar to Polyribonucleotide nucleotidyltransferase [Streptococcus pyogenes MGAS10394]; polynucleotide phosphorylase/polyadenylase 242626 8111355 SDEG_0259 Streptococcus dysgalactiae subsp. equisimilis GGS_124 polynucleotide phosphorylase/polyadenylase YP_002995990.1 240482 D 486410 CDS YP_002995991.1 251781689 8111356 242619..243371 1 NC_012891.1 similar to hypothetical protein M6 Spy1667 [Streptococcus pyogenes MGAS10394]; hypothetical protein 243371 8111356 SDEG_0260 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002995991.1 242619 D 486410 CDS YP_002995992.1 251781690 8111357 243380..243964 1 NC_012891.1 similar to serine acetyltransferase [Streptococcus pyogenes MGAS10394]; serine acetyltransferase 243964 8111357 SDEG_0261 Streptococcus dysgalactiae subsp. equisimilis GGS_124 serine acetyltransferase YP_002995992.1 243380 D 486410 CDS YP_002995993.1 251781691 8111358 244215..244445 1 NC_012891.1 similar to hypothetical protein M5005 Spy 1656 [Streptococcus pyogenes MGAS5005]; hypothetical protein 244445 8111358 SDEG_0262 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002995993.1 244215 D 486410 CDS YP_002995994.1 251781692 8111359 244473..245816 1 NC_012891.1 catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA; cysteinyl-tRNA synthetase 245816 cysS 8111359 cysS Streptococcus dysgalactiae subsp. equisimilis GGS_124 cysteinyl-tRNA synthetase YP_002995994.1 244473 D 486410 CDS YP_002995995.1 251781693 8111658 245809..246210 1 NC_012891.1 similar to hypothetical protein SpyM51627 [Streptococcus pyogenes str. Manfredo]; hypothetical protein 246210 8111658 SDEG_0264 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002995995.1 245809 D 486410 CDS YP_002995996.1 251781694 8111360 246327..246653 1 NC_012891.1 similar to conserved hypothetical protein [Enterococcus faecium DO]; hypothetical protein 246653 8111360 SDEG_0265 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002995996.1 246327 D 486410 CDS YP_002995997.1 251781695 8111361 246845..247357 1 NC_012891.1 similar to hypothetical protein EF3281 [Enterococcus faecalis V583]; hypothetical protein 247357 8111361 SDEG_0266 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002995997.1 246845 D 486410 CDS YP_002995998.1 251781696 8111362 247768..248493 1 NC_012891.1 similar to hypothetical membrane associated protein [Streptococcus pyogenes MGAS2096]; hypothetical protein 248493 8111362 SDEG_0267 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002995998.1 247768 D 486410 CDS YP_002995999.1 251781697 8111363 248600..249346 1 NC_012891.1 similar to 23S rRNA Gm2251 methyltransferase [Streptococcus pyogenes MGAS10394]; 23S rRNA Gm2251-methyltransferase 249346 8111363 SDEG_0268 Streptococcus dysgalactiae subsp. equisimilis GGS_124 23S rRNA Gm2251-methyltransferase YP_002995999.1 248600 D 486410 CDS YP_002996000.1 251781698 8111364 249350..249868 1 NC_012891.1 similar to hypothetical protein SpyM51624 [Streptococcus pyogenes str. Manfredo]; hypothetical protein 249868 8111364 SDEG_0269 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996000.1 249350 D 486410 CDS YP_002996001.1 251781699 8111365 249952..250827 1 NC_012891.1 similar to DegV family protein [Streptococcus pyogenes MGAS10394]; DegV family protein 250827 8111365 SDEG_0270 Streptococcus dysgalactiae subsp. equisimilis GGS_124 DegV family protein YP_002996001.1 249952 D 486410 CDS YP_002996002.1 251781700 8111366 250962..251660 1 NC_012891.1 similar to hypothetical membrane spanning protein [Streptococcus pyogenes MGAS10394]; hypothetical protein 251660 8111366 SDEG_0271 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996002.1 250962 D 486410 CDS YP_002996003.1 251781701 8111367 251657..251863 1 NC_012891.1 similar to Cro/CI family transcriptional regulator [Streptococcus pyogenes MGAS6180]; Cro/CI family transcriptional regulator 251863 8111367 SDEG_0272 Streptococcus dysgalactiae subsp. equisimilis GGS_124 Cro/CI family transcriptional regulator YP_002996003.1 251657 D 486410 CDS YP_002996004.1 251781702 8111368 251995..252114 1 NC_012891.1 similar to transposase [Streptococcus pyogenes MGAS10394]; transposase 252114 8111368 SDEG_0273 Streptococcus dysgalactiae subsp. equisimilis GGS_124 transposase YP_002996004.1 251995 D 486410 CDS YP_002996005.1 251781703 8111369 252188..252280 1 NC_012891.1 similar to transposase [Streptococcus pyogenes MGAS5005]; transposase 252280 8111369 SDEG_0274 Streptococcus dysgalactiae subsp. equisimilis GGS_124 transposase YP_002996005.1 252188 D 486410 CDS YP_002996006.1 251781704 8111370 252277..252507 1 NC_012891.1 similar to transposase [Streptococcus pyogenes MGAS10750]; transposase 252507 8111370 SDEG_0275 Streptococcus dysgalactiae subsp. equisimilis GGS_124 transposase YP_002996006.1 252277 D 486410 CDS YP_002996007.1 251781705 8111371 252596..253021 1 NC_012891.1 similar to transposase [Streptococcus pyogenes MGAS10270]; transposase 253021 8111371 SDEG_0276 Streptococcus dysgalactiae subsp. equisimilis GGS_124 transposase YP_002996007.1 252596 D 486410 CDS YP_002996008.1 251781706 8111372 253152..253703 1 NC_012891.1 in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit; 50S ribosomal protein L13 253703 rplM 8111372 rplM Streptococcus dysgalactiae subsp. equisimilis GGS_124 50S ribosomal protein L13 YP_002996008.1 253152 D 486410 CDS YP_002996009.1 251781707 8111373 253724..254116 1 NC_012891.1 forms a direct contact with the tRNA during translation; 30S ribosomal protein S9 254116 rpsI 8111373 rpsI Streptococcus dysgalactiae subsp. equisimilis GGS_124 30S ribosomal protein S9 YP_002996009.1 253724 D 486410 CDS YP_002996010.1 251781708 8111100 complement(254244..255398) 1 NC_012891.1 similar to phage integrase family site specific recombinase [Streptococcus agalactiae A909]; site-specific recombinase, phage integrase family 255398 8111100 SDEG_0279 Streptococcus dysgalactiae subsp. equisimilis GGS_124 site-specific recombinase, phage integrase family YP_002996010.1 254244 R 486410 CDS YP_002996011.1 251781709 8111374 complement(255462..256052) 1 NC_012891.1 similar to transcriptional regulator Cro/CI family [Streptococcus agalactiae CJB111]; Cro/CI family transcriptional regulator 256052 8111374 SDEG_0280 Streptococcus dysgalactiae subsp. equisimilis GGS_124 Cro/CI family transcriptional regulator YP_002996011.1 255462 R 486410 CDS YP_002996012.1 251781710 8111375 256207..256512 1 NC_012891.1 similar to hypothetical protein SAG0219 [Streptococcus agalactiae 2603V/R]; hypothetical protein 256512 8111375 SDEG_0281 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996012.1 256207 D 486410 CDS YP_002996013.1 251781711 8111376 256649..256927 1 NC_012891.1 similar to hypothetical protein SAG0220 [Streptococcus agalactiae 2603V/R]; hypothetical protein 256927 8111376 SDEG_0282 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996013.1 256649 D 486410 CDS YP_002996014.1 251781712 8111377 256938..257168 1 NC_012891.1 similar to hypothetical protein SAG0221 [Streptococcus agalactiae 2603V/R]; hypothetical protein 257168 8111377 SDEG_0283 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996014.1 256938 D 486410 CDS YP_002996015.1 251781713 8111378 257181..257507 1 NC_012891.1 similar to hypothetical protein SAG0222 [Streptococcus agalactiae 2603V/R]; hypothetical protein 257507 8111378 SDEG_0284 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996015.1 257181 D 486410 CDS YP_002996016.1 251781714 8111379 257511..258140 1 NC_012891.1 similar to conserved hypothetical protein [Streptococcus agalactiae CJB111]; hypothetical protein 258140 8111379 SDEG_0285 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996016.1 257511 D 486410 CDS YP_002996017.1 251781715 8111381 259365..259799 1 NC_012891.1 similar to hypothetical protein SAG0225 [Streptococcus agalactiae 2603V/R]; hypothetical protein 259799 8111381 SDEG_0287 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996017.1 259365 D 486410 CDS YP_002996018.1 251781716 8111382 260115..261371 1 NC_012891.1 similar to recombination protein [Streptococcus agalactiae 2603V/R]; recombination protein 261371 8111382 SDEG_0288 Streptococcus dysgalactiae subsp. equisimilis GGS_124 recombination protein YP_002996018.1 260115 D 486410 CDS YP_002996019.1 251781717 8111383 261539..262009 1 NC_012891.1 similar to hypothetical protein SAG0227 [Streptococcus agalactiae 2603V/R]; hypothetical protein 262009 8111383 SDEG_0289 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996019.1 261539 D 486410 CDS YP_002996020.1 251781718 8111384 complement(262314..262649) 1 NC_012891.1 similar to hypothetical protein SAG0228 [Streptococcus agalactiae 2603V/R]; hypothetical protein 262649 8111384 SDEG_0290 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996020.1 262314 R 486410 CDS YP_002996021.1 251781719 8111385 complement(262639..262926) 1 NC_012891.1 similar to hypothetical protein SAG0229 [Streptococcus agalactiae 2603V/R]; hypothetical protein 262926 8111385 SDEG_0291 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996021.1 262639 R 486410 CDS YP_002996022.1 251781720 8111386 complement(263330..264040) 1 NC_012891.1 similar to phage integrase family integrase/recombinase [Streptococcus thermophilus LMG 18311]; integrase/recombinase, phage integrase family 264040 int 8111386 int Streptococcus dysgalactiae subsp. equisimilis GGS_124 integrase/recombinase, phage integrase family YP_002996022.1 263330 R 486410 CDS YP_002996023.1 251781721 8110868 complement(264073..264459) 1 NC_012891.1 similar to transposase [Streptococcus pyogenes MGAS9429]; transposase 264459 8110868 SDEG_0293 Streptococcus dysgalactiae subsp. equisimilis GGS_124 transposase YP_002996023.1 264073 R 486410 CDS YP_002996024.1 251781722 8111387 complement(264511..264933) 1 NC_012891.1 similar to transposase [Streptococcus pyogenes MGAS2096]; transposase 264933 8111387 SDEG_0294 Streptococcus dysgalactiae subsp. equisimilis GGS_124 transposase YP_002996024.1 264511 R 486410 CDS YP_002996025.1 251781723 8111388 265043..266161 1 NC_012891.1 similar to lantibiotic biosynthesis protein [Streptococcus thermophilus LMG 18311]; lantibiotic biosynthesis protein 266161 labC 8111388 labC Streptococcus dysgalactiae subsp. equisimilis GGS_124 lantibiotic biosynthesis protein YP_002996025.1 265043 D 486410 CDS YP_002996026.1 251781724 8110880 266191..267456 1 NC_012891.1 similar to lantibiotic efflux protein [Streptococcus thermophilus CNRZ1066]; lantibiotic efflux protein 267456 labT 8110880 labT Streptococcus dysgalactiae subsp. equisimilis GGS_124 lantibiotic efflux protein YP_002996026.1 266191 D 486410 CDS YP_002996027.1 251781725 8110881 267515..267952 1 NC_012891.1 similar to ATP-dependent DNA helicase recG [Streptococcus agalactiae 515]; ATP-dependent DNA helicase 267952 8110881 SDEG_0297 Streptococcus dysgalactiae subsp. equisimilis GGS_124 ATP-dependent DNA helicase YP_002996027.1 267515 D 486410 CDS YP_002996028.1 251781726 8111389 268034..268201 1 NC_012891.1 similar to predicted transcriptional regulator containing HTH domain [Streptococcus thermophilus LMD-9]; transcriptional regulator containing HTH domain 268201 8111389 SDEG_0298 Streptococcus dysgalactiae subsp. equisimilis GGS_124 transcriptional regulator containing HTH domain YP_002996028.1 268034 D 486410 CDS YP_002996029.1 251781727 8111390 complement(268695..269963) 1 NC_012891.1 similar to 5-methylcytosine methyltransferase [Lactococcus lactis subsp. lactis bv. diacetylactis]; 5-methylcytosine methyltransferase 269963 8111390 SDEG_0299 Streptococcus dysgalactiae subsp. equisimilis GGS_124 5-methylcytosine methyltransferase YP_002996029.1 268695 R 486410 CDS YP_002996030.1 251781728 8111391 270078..271568 1 NC_012891.1 similar to restriction enzyme [Lactococcus lactis subsp. lactis bv. diacetylactis]; restriction enzyme 271568 8111391 SDEG_0300 Streptococcus dysgalactiae subsp. equisimilis GGS_124 restriction enzyme YP_002996030.1 270078 D 486410 CDS YP_002996031.1 251781729 8111392 271580..271930 1 NC_012891.1 no hit; hypothetical protein 271930 8111392 SDEG_0301 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996031.1 271580 D 486410 CDS YP_002996032.1 251781730 8111394 273732..274301 1 NC_012891.1 no hit; hypothetical protein 274301 8111394 SDEG_0303 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996032.1 273732 D 486410 CDS YP_002996033.1 251781731 8111395 275079..277028 1 NC_012891.1 similar to hypothetical protein CLOSS21 00385 [Clostridium sp. SS2/1]; hypothetical protein 277028 8111395 SDEG_0304 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996033.1 275079 D 486410 CDS YP_002996034.1 251781732 8111396 277030..277488 1 NC_012891.1 similar to PTS system galactitol-specific IIA component [Streptococcus agalactiae A909]; PTS system galactitol-specific transporter subunit IIA 277488 8111396 SDEG_0305 Streptococcus dysgalactiae subsp. equisimilis GGS_124 PTS system galactitol-specific transporter subunit IIA YP_002996034.1 277030 D 486410 CDS YP_002996035.1 251781733 8111397 277498..278838 1 NC_012891.1 similar to PTS system galactitol-specific IIC component [Streptococcus agalactiae A909]; PTS system galactitol-specific transporter subunit IIC 278838 8111397 SDEG_0306 Streptococcus dysgalactiae subsp. equisimilis GGS_124 PTS system galactitol-specific transporter subunit IIC YP_002996035.1 277498 D 486410 CDS YP_002996036.1 251781734 8111398 278835..279119 1 NC_012891.1 similar to PTS system galactitol-specific IIB component [Streptococcus agalactiae A909]; PTS system galactitol-specific transporter subunit IIB 279119 8111398 SDEG_0307 Streptococcus dysgalactiae subsp. equisimilis GGS_124 PTS system galactitol-specific transporter subunit IIB YP_002996036.1 278835 D 486410 CDS YP_002996037.1 251781735 8111399 279121..279960 1 NC_012891.1 similar to hypothetical protein ANACAC 03037 [anaerostipes caccae DSM 14662]; hypothetical protein 279960 8111399 SDEG_0308 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996037.1 279121 D 486410 CDS YP_002996038.1 251781736 8111400 279960..280637 1 NC_012891.1 similar to hypothetical protein ANACAC 03039 [anaerostipes caccae DSM 14662]; hypothetical protein 280637 8111400 SDEG_0309 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996038.1 279960 D 486410 CDS YP_002996039.1 251781737 8111401 280649..281170 1 NC_012891.1 similar to hypothetical protein ANACAC 03038 [anaerostipes caccae DSM 14662]; hypothetical protein 281170 8111401 SDEG_0310 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996039.1 280649 D 486410 CDS YP_002996040.1 251781738 8111402 281418..282233 1 NC_012891.1 similar to hypothetical protein CLOL250 01537 [Clostridium sp. L2-50]; hypothetical protein 282233 8111402 SDEG_0311 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996040.1 281418 D 486410 CDS YP_002996041.1 251781739 8111409 287809..288291 1 NC_012891.1 similar to competence protein ComX1 [Streptococcus pyogenes MGAS315]; competence protein ComX1 288291 comX.2 8111409 comX.2 Streptococcus dysgalactiae subsp. equisimilis GGS_124 competence protein ComX1 YP_002996041.1 287809 D 486410 CDS YP_002996042.1 251781740 8111637 complement(288523..289872) 1 NC_012891.1 catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP; lysine and threonine sensitive; aspartate kinase 289872 8111637 SDEG_0319 Streptococcus dysgalactiae subsp. equisimilis GGS_124 aspartate kinase YP_002996042.1 288523 R 486410 CDS YP_002996043.1 251781741 8111410 290018..290767 1 NC_012891.1 mediates pseudouridylation (positions 38, 39, 40) at the tRNA anticodon region which contributes to the structural stability; tRNA pseudouridine synthase A 290767 truA 8111410 truA Streptococcus dysgalactiae subsp. equisimilis GGS_124 tRNA pseudouridine synthase A YP_002996043.1 290018 D 486410 CDS YP_002996044.1 251781742 8111930 290757..291524 1 NC_012891.1 catalyzes the formation of 4-amino-2-methyl-5-diphosphomethylpyrimidine; phosphomethylpyrimidine kinase 291524 8111930 SDEG_0321 Streptococcus dysgalactiae subsp. equisimilis GGS_124 phosphomethylpyrimidine kinase YP_002996044.1 290757 D 486410 CDS YP_002996045.1 251781743 8111411 291508..291984 1 NC_012891.1 similar to hypothetical membrane spanning protein [Streptococcus pyogenes MGAS5005]; hypothetical protein 291984 8111411 SDEG_0322 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996045.1 291508 D 486410 CDS YP_002996046.1 251781744 8111412 291995..292558 1 NC_012891.1 similar to hypothetical protein M28 Spy1603 [Streptococcus pyogenes MGAS6180]; hypothetical protein 292558 8111412 SDEG_0323 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996046.1 291995 D 486410 CDS YP_002996047.1 251781745 8111413 complement(292621..293466) 1 NC_012891.1 similar to conserved hypothetical protein possible mechanosensitive ion channel [Streptococcuspyogenes NZ131]; potassium efflux system/small-conductance mechanosensitive channel 293466 8111413 SDEG_0324 Streptococcus dysgalactiae subsp. equisimilis GGS_124 potassium efflux system/small-conductance mechanosensitive channel YP_002996047.1 292621 R 486410 CDS YP_002996048.1 251781746 8111414 293860..295263 1 NC_012891.1 similar to alpha-amylase precursor AmyE [Streptococcus equi subsp. zooepidemicus MGCS10565]; alpha-amylase 295263 amyE 8111414 amyE Streptococcus dysgalactiae subsp. equisimilis GGS_124 alpha-amylase YP_002996048.1 293860 D 486410 CDS YP_002996049.1 251781747 8112324 295486..296892 1 NC_012891.1 similar to alpha-amylase precursor AmyE [Streptococcus equi subsp. zooepidemicus MGCS10565]; alpha-amylase 296892 amyE 8112324 amyE Streptococcus dysgalactiae subsp. equisimilis GGS_124 alpha-amylase YP_002996049.1 295486 D 486410 CDS YP_002996050.1 251781748 8112325 297013..298383 1 NC_012891.1 Tig; RopA; peptidyl-prolyl cis/trans isomerase; promotes folding of newly synthesized proteins; binds ribosomal 50S subunit; forms a homodimer; trigger factor 298383 tig 8112325 tig Streptococcus dysgalactiae subsp. equisimilis GGS_124 trigger factor YP_002996050.1 297013 D 486410 CDS YP_002996051.1 251781749 8111055 298597..299175 1 NC_012891.1 participates in both the initiation and recycling phases of transcription; in the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling; DNA-directed RNA polymerase subunit delta 299175 8111055 SDEG_0328 Streptococcus dysgalactiae subsp. equisimilis GGS_124 DNA-directed RNA polymerase subunit delta YP_002996051.1 298597 D 486410 CDS YP_002996052.1 251781750 8111415 299458..301062 1 NC_012891.1 CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer; CTP synthetase 301062 pyrG 8111415 pyrG Streptococcus dysgalactiae subsp. equisimilis GGS_124 CTP synthetase YP_002996052.1 299458 D 486410 CDS YP_002996053.1 251781751 8111343 301138..302898 1 NC_012891.1 similar to autolysin sensor kinase protein [Staphylococcus aureus subsp. aureus MRSA252]; autolysin sensor kinase protein 302898 lytS 8111343 lytS Streptococcus dysgalactiae subsp. equisimilis GGS_124 autolysin sensor kinase protein YP_002996053.1 301138 D 486410 CDS YP_002996054.1 251781752 8110915 302895..303623 1 NC_012891.1 similar to two-component response regulator LytR [Carnobacterium sp. AT7]; two-component response regulator 303623 lytR 8110915 lytR Streptococcus dysgalactiae subsp. equisimilis GGS_124 two-component response regulator YP_002996054.1 302895 D 486410 CDS YP_002996055.1 251781753 8110914 303719..304204 1 NC_012891.1 similar to murein hydrolase regulator LrgA [Staphylococcus aureus subsp. aureus JH9]; murein hydrolase regulator 304204 lrgA 8110914 lrgA Streptococcus dysgalactiae subsp. equisimilis GGS_124 murein hydrolase regulator YP_002996055.1 303719 D 486410 CDS YP_002996056.1 251781754 8110909 304222..304929 1 NC_012891.1 in conjunction with LrgA this protein inhibits the expression or activity of extracellular murein hydrolases; antiholin-like protein LrgB 304929 lrgB 8110909 lrgB Streptococcus dysgalactiae subsp. equisimilis GGS_124 antiholin-like protein LrgB YP_002996056.1 304222 D 486410 CDS YP_002996057.1 251781755 8110910 305089..306015 1 NC_012891.1 similar to alpha /beta hydrolase [Streptococcus pyogenes MGAS10394]; alpha/beta hydrolase 306015 8110910 SDEG_0334 Streptococcus dysgalactiae subsp. equisimilis GGS_124 alpha/beta hydrolase YP_002996057.1 305089 D 486410 CDS YP_002996058.1 251781756 8111417 306360..307241 1 NC_012891.1 catalyzes the formation of glycerone phosphate and glyceraldehyde 3-phosphate from fructose 1,6, bisphosphate; fructose-bisphosphate aldolase 307241 8111417 SDEG_0336 Streptococcus dysgalactiae subsp. equisimilis GGS_124 fructose-bisphosphate aldolase YP_002996058.1 306360 D 486410 CDS YP_002996059.1 251781757 8111418 307765..308049 1 NC_012891.1 similar to transposase [Streptococcus pyogenes MGAS315]; transposase 308049 8111418 SDEG_0337 Streptococcus dysgalactiae subsp. equisimilis GGS_124 transposase YP_002996059.1 307765 D 486410 CDS YP_002996060.1 251781758 8111419 308046..308792 1 NC_012891.1 similar to transposase [Streptococcus pyogenes MGAS10270]; transposase 308792 8111419 SDEG_0338 Streptococcus dysgalactiae subsp. equisimilis GGS_124 transposase YP_002996060.1 308046 D 486410 CDS YP_002996061.1 251781759 8111420 308963..309151 1 NC_012891.1 required for 70S ribosome assembly; 50S ribosomal protein L28 309151 rpmB 8111420 rpmB Streptococcus dysgalactiae subsp. equisimilis GGS_124 50S ribosomal protein L28 YP_002996061.1 308963 D 486410 CDS YP_002996062.1 251781760 8111080 309305..309670 1 NC_012891.1 similar to alkaline-shock protein [Streptococcus pyogenes M1 GAS]; alkaline-shock protein 309670 8111080 SDEG_0340 Streptococcus dysgalactiae subsp. equisimilis GGS_124 alkaline-shock protein YP_002996062.1 309305 D 486410 CDS YP_002996063.1 251781761 8111421 309670..311334 1 NC_012891.1 similar to hypothetical protein spyM18 1950 [Streptococcus pyogenes MGAS8232]; hypothetical protein 311334 8111421 SDEG_0341 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996063.1 309670 D 486410 CDS YP_002996064.1 251781762 8111422 311570..312460 1 NC_012891.1 similar to membrane protease protein family [Streptococcus pyogenes MGAS10394]; membrane protease protein family 312460 8111422 SDEG_0342 Streptococcus dysgalactiae subsp. equisimilis GGS_124 membrane protease protein family YP_002996064.1 311570 D 486410 CDS YP_002996065.1 251781763 8111423 complement(312856..313665) 1 NC_012891.1 similar to amino acid transport ATP-binding protein [Streptococcus pyogenes MGAS10394]; amino acid ABC transporter ATP-binding protein 313665 8111423 SDEG_0343 Streptococcus dysgalactiae subsp. equisimilis GGS_124 amino acid ABC transporter ATP-binding protein YP_002996065.1 312856 R 486410 CDS YP_002996066.1 251781764 8111424 complement(313589..315175) 1 NC_012891.1 similar to ABC transporter amino acid-binding protein [Streptococcus pyogenes MGAS10394]; amino acid ABC transporter substrate-binding protein 315175 8111424 SDEG_0344 Streptococcus dysgalactiae subsp. equisimilis GGS_124 amino acid ABC transporter substrate-binding protein YP_002996066.1 313589 R 486410 CDS YP_002996067.1 251781765 8111425 315356..317281 1 NC_012891.1 similar to hypothetical membrane spanning protein [Streptococcus pyogenes MGAS2096]; hypothetical protein 317281 8111425 SDEG_0345 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996067.1 315356 D 486410 CDS YP_002996068.1 251781766 8111426 317347..318186 1 NC_012891.1 BacA; phosphatase activity in Escherichia coli not kinase; involved in bacitracin resistance as bacitracin supposedly sequesters undecaprenyl disphosphate which reduces the pool of lipid carrier available to the cell; UDP pyrophosphate phosphatase 318186 bacA 8111426 bacA Streptococcus dysgalactiae subsp. equisimilis GGS_124 UDP pyrophosphate phosphatase YP_002996068.1 317347 D 486410 CDS YP_002996069.1 251781767 8112365 318324..319091 1 NC_012891.1 enables recognition and targeting of proteins for proteolysis, involved in negative regulation of competence; adaptor protein 319091 mecA 8112365 mecA Streptococcus dysgalactiae subsp. equisimilis GGS_124 adaptor protein YP_002996069.1 318324 D 486410 CDS YP_002996070.1 251781768 8110934 319098..320267 1 NC_012891.1 similar to undecaprenyl-phosphate alpha-N-acetylglucosaminephosphotransferase [Streptococcus pyogenes MGAS10750]; UDP-phosphate-alpha-N- acetylglucosaminyltransferase 320267 8110934 SDEG_0348 Streptococcus dysgalactiae subsp. equisimilis GGS_124 UDP-phosphate-alpha-N- acetylglucosaminyltransferase YP_002996070.1 319098 D 486410 CDS YP_002996071.1 251781769 8111427 320380..321150 1 NC_012891.1 similar to ATP-dependent transporter sufC [Streptococcus pyogenes MGAS2096]; ATP-dependent transporter 321150 sufC 8111427 sufC Streptococcus dysgalactiae subsp. equisimilis GGS_124 ATP-dependent transporter YP_002996071.1 320380 D 486410 CDS YP_002996072.1 251781770 8110508 321246..322508 1 NC_012891.1 similar to SufD protein [Streptococcus pyogenes MGAS10270]; iron-sulfur cluster assembly protein 322508 sufD 8110508 sufD Streptococcus dysgalactiae subsp. equisimilis GGS_124 iron-sulfur cluster assembly protein YP_002996072.1 321246 D 486410 CDS YP_002996073.1 251781771 8110509 322539..323765 1 NC_012891.1 similar to aminotransferase [Streptococcus pyogenes MGAS315]; aminotransferase 323765 sufS 8110509 sufS Streptococcus dysgalactiae subsp. equisimilis GGS_124 aminotransferase YP_002996073.1 322539 D 486410 CDS YP_002996074.1 251781772 8110510 323752..324228 1 NC_012891.1 similar to IscU [Streptococcus pyogenes MGAS10394]; iron-sulfur cluster assembly scaffold protein 324228 iscU 8110510 iscU Streptococcus dysgalactiae subsp. equisimilis GGS_124 iron-sulfur cluster assembly scaffold protein YP_002996074.1 323752 D 486410 CDS YP_002996075.1 251781773 8110872 324221..325639 1 NC_012891.1 similar to hypothetical protein spyM18 0278 [Streptococcus pyogenes MGAS8232]; hypothetical protein 325639 8110872 SDEG_0353 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996075.1 324221 D 486410 CDS YP_002996076.1 251781774 8111428 complement(325815..326996) 1 NC_012891.1 similar to D-alanyl-D-alanine carboxypeptidase [Streptococcus pyogenes MGAS10270]; D-alanyl-D-alanine carboxypeptidase 326996 8111428 SDEG_0354 Streptococcus dysgalactiae subsp. equisimilis GGS_124 D-alanyl-D-alanine carboxypeptidase YP_002996076.1 325815 R 486410 CDS YP_002996077.1 251781775 8111429 complement(327140..328378) 1 NC_012891.1 similar to D-alanyl-D-alanine carboxypeptidase [Streptococcus pyogenes MGAS315]; D-alanyl-D-alanine carboxypeptidase 328378 dacA 8111429 dacA Streptococcus dysgalactiae subsp. equisimilis GGS_124 D-alanyl-D-alanine carboxypeptidase YP_002996077.1 327140 R 486410 CDS YP_002996078.1 251781776 8111660 328700..330679 1 NC_012891.1 similar to oligopeptide-binding protein [Streptococcus pyogenes MGAS6180]; oligopeptide-binding protein 330679 oppA 8111660 oppA Streptococcus dysgalactiae subsp. equisimilis GGS_124 oligopeptide-binding protein YP_002996078.1 328700 D 486410 CDS YP_002996079.1 251781777 8111733 330733..332247 1 NC_012891.1 similar to oligopeptide transport system permease protein oppB [Streptococcus pyogenes MGAS10750]; oligopeptide transport system permease 332247 oppB 8111733 oppB Streptococcus dysgalactiae subsp. equisimilis GGS_124 oligopeptide transport system permease YP_002996079.1 330733 D 486410 CDS YP_002996080.1 251781778 8111735 332247..333173 1 NC_012891.1 similar to oligopeptide permease [Streptococcus pyogenes MGAS8232]; oligopeptide permease 333173 oppC 8111735 oppC Streptococcus dysgalactiae subsp. equisimilis GGS_124 oligopeptide permease YP_002996080.1 332247 D 486410 CDS YP_002996081.1 251781779 8111737 333182..334252 1 NC_012891.1 similar to oligopeptide transport ATP-binding protein [Streptococcus pyogenes MGAS6180]; oligopeptide transport ATP-binding protein 334252 oppD 8111737 oppD Streptococcus dysgalactiae subsp. equisimilis GGS_124 oligopeptide transport ATP-binding protein YP_002996081.1 333182 D 486410 CDS YP_002996082.1 251781780 8111739 334245..335168 1 NC_012891.1 similar to oligopeptide ABC transporter, ATP-binding protein [Streptococcus pyogenes MGAS315]; oligopeptide ABC transporter ATP-binding protein 335168 oppF 8111739 oppF Streptococcus dysgalactiae subsp. equisimilis GGS_124 oligopeptide ABC transporter ATP-binding protein YP_002996082.1 334245 D 486410 CDS YP_002996083.1 251781781 8112055 343571..344155 1 NC_012891.1 similar to lipase [Streptococcus pyogenes MGAS10394]; lipase 344155 8112055 SDEG_0367 Streptococcus dysgalactiae subsp. equisimilis GGS_124 lipase YP_002996083.1 343571 D 486410 CDS YP_002996084.1 251781782 8112056 344155..345273 1 NC_012891.1 in Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis; GTP-binding protein YqeH 345273 8112056 SDEG_0368 Streptococcus dysgalactiae subsp. equisimilis GGS_124 GTP-binding protein YqeH YP_002996084.1 344155 D 486410 CDS YP_002996085.1 251781783 8112057 345218..345607 1 NC_012891.1 similar to hypothetical RNA binding protein [Streptococcus pyogenes MGAS10394]; RNA binding protein 345607 8112057 SDEG_0369 Streptococcus dysgalactiae subsp. equisimilis GGS_124 RNA binding protein YP_002996085.1 345218 D 486410 CDS YP_002996086.1 251781784 8112058 345676..346308 1 NC_012891.1 transfers an adenyl group from ATP to NaMN to form nicotinic acid adenine dinucleotide (NaAD) which is then converted to the ubiquitous compound NAD by NAD synthetase; essential enzyme in bacteria; nicotinic acid mononucleotide adenylyltransferase 346308 nadD 8112058 nadD Streptococcus dysgalactiae subsp. equisimilis GGS_124 nicotinic acid mononucleotide adenylyltransferase YP_002996086.1 345676 D 486410 CDS YP_002996087.1 251781785 8111704 346305..346898 1 NC_012891.1 similar to hydrolase (HAD superfamily) [Streptococcus pyogenes MGAS10394]; HAD superfamily hydrolase 346898 8111704 SDEG_0371 Streptococcus dysgalactiae subsp. equisimilis GGS_124 HAD superfamily hydrolase YP_002996087.1 346305 D 486410 CDS YP_002996088.1 251781786 8112059 346874..347134 1 NC_012891.1 similar to isochorismatase [Streptococcus pyogenes MGAS10750]; isochorismatase 347134 8112059 SDEG_0372 Streptococcus dysgalactiae subsp. equisimilis GGS_124 isochorismatase YP_002996088.1 346874 D 486410 CDS YP_002996089.1 251781787 8112060 347124..347489 1 NC_012891.1 similar to iojap protein family [Streptococcus pyogenes MGAS10394]; iojap protein family 347489 8112060 SDEG_0373 Streptococcus dysgalactiae subsp. equisimilis GGS_124 iojap protein family YP_002996089.1 347124 D 486410 CDS YP_002996090.1 251781788 8112061 347525..348280 1 NC_012891.1 similar to methyltransferase [Streptococcus pyogenes MGAS10394]; methyltransferase 348280 8112061 SDEG_0374 Streptococcus dysgalactiae subsp. equisimilis GGS_124 methyltransferase YP_002996090.1 347525 D 486410 CDS YP_002996091.1 251781789 8112062 348355..349452 1 NC_012891.1 similar to hypothetical protein stu1615 [Streptococcus thermophilus LMG 18311]; hypothetical protein 349452 8112062 SDEG_0375 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996091.1 348355 D 486410 CDS YP_002996092.1 251781790 8112063 349555..350268 1 NC_012891.1 similar to transcriptional regulator MerR family [Streptococcus equi subsp. zooepidemicus MGCS10565]; MerR family transcriptional regulator 350268 8112063 SDEG_0376 Streptococcus dysgalactiae subsp. equisimilis GGS_124 MerR family transcriptional regulator YP_002996092.1 349555 D 486410 CDS YP_002996093.1 251781791 8112064 350879..352300 1 NC_012891.1 similar to internalin A-like histidine triad lipoprotein [Streptococcus equi subsp. zooepidemicus MGCS10565]; internalin A-like histidine triad lipoprotein 352300 8112064 SDEG_0377 Streptococcus dysgalactiae subsp. equisimilis GGS_124 internalin A-like histidine triad lipoprotein YP_002996093.1 350879 D 486410 CDS YP_002996094.1 251781792 8112065 352353..353300 1 NC_012891.1 no hit; hypothetical protein 353300 8112065 SDEG_0378 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996094.1 352353 D 486410 CDS YP_002996095.1 251781793 8112066 353464..354390 1 NC_012891.1 similar to biotin synthetase [Streptococcus agalactiae 2603V/R]; biotin synthetase 354390 bioB 8112066 bioB Streptococcus dysgalactiae subsp. equisimilis GGS_124 biotin synthetase YP_002996095.1 353464 D 486410 CDS YP_002996096.1 251781794 8112375 354559..355275 1 NC_012891.1 similar to hypothetical protein M6 Spy0297 [Streptococcus pyogenes MGAS10394]; hypothetical protein 355275 8112375 SDEG_0380 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996096.1 354559 D 486410 CDS YP_002996097.1 251781795 8112067 355483..356325 1 NC_012891.1 similar to ABC transporter substrate-binding protein [Streptococcus pyogenes MGAS10394]; ABC transporter substrate-binding protein 356325 8112067 SDEG_0381 Streptococcus dysgalactiae subsp. equisimilis GGS_124 ABC transporter substrate-binding protein YP_002996097.1 355483 D 486410 CDS YP_002996098.1 251781796 8112068 356480..357334 1 NC_012891.1 similar to ABC transporter substrate-binding protein [Streptococcus pyogenes MGAS10394]; ABC transporter substrate-binding protein 357334 8112068 SDEG_0382 Streptococcus dysgalactiae subsp. equisimilis GGS_124 ABC transporter substrate-binding protein YP_002996098.1 356480 D 486410 CDS YP_002996099.1 251781797 8112069 357512..358357 1 NC_012891.1 similar to ABC transporter substrate-binding protein [Streptococcus pyogenes MGAS10394]; ABC transporter substrate-binding protein 358357 8112069 SDEG_0383 Streptococcus dysgalactiae subsp. equisimilis GGS_124 ABC transporter substrate-binding protein YP_002996099.1 357512 D 486410 CDS YP_002996100.1 251781798 8112070 358432..359805 1 NC_012891.1 similar to acetylornithine deacetylase /succinyl-diaminopimelate desuccinylase (M20/M25/M40 family peptidase), [Streptococcus sanguinis SK36]; acetylornithine deacetylase 359805 dapE 8112070 dapE Streptococcus dysgalactiae subsp. equisimilis GGS_124 acetylornithine deacetylase YP_002996100.1 358432 D 486410 CDS YP_002996101.1 251781799 8111661 359798..360862 1 NC_012891.1 similar to ABC transporter ATP-binding protein [Streptococcus pyogenes MGAS10394]; ABC transporter ATP-binding protein 360862 8111661 SDEG_0385 Streptococcus dysgalactiae subsp. equisimilis GGS_124 ABC transporter ATP-binding protein YP_002996101.1 359798 D 486410 CDS YP_002996102.1 251781800 8112071 360863..361555 1 NC_012891.1 similar to ABC transporter permease protein [Streptococcus pyogenes MGAS10394]; ABC transporter permease 361555 8112071 SDEG_0386 Streptococcus dysgalactiae subsp. equisimilis GGS_124 ABC transporter permease YP_002996102.1 360863 D 486410 CDS YP_002996103.1 251781801 8112072 complement(361609..362979) 1 NC_012891.1 similar to Branched-chain amino acid transport system carrier protein [Streptococcus pyogenes MGAS10394]; branched-chain amino acid transport system carrier protein 362979 8112072 SDEG_0387 Streptococcus dysgalactiae subsp. equisimilis GGS_124 branched-chain amino acid transport system carrier protein YP_002996103.1 361609 R 486410 CDS YP_002996104.1 251781802 8112073 363220..364434 1 NC_012891.1 involved in the import of serine and threonine coupled with the import of sodium; serine/threonine transporter SstT 364434 8112073 SDEG_0388 Streptococcus dysgalactiae subsp. equisimilis GGS_124 serine/threonine transporter SstT YP_002996104.1 363220 D 486410 CDS YP_002996105.1 251781803 8112074 complement(364492..365166) 1 NC_012891.1 similar to KtrA [Streptococcus pyogenes MGAS10394]; potassium uptake protein 365166 ktrA 8112074 ktrA Streptococcus dysgalactiae subsp. equisimilis GGS_124 potassium uptake protein YP_002996105.1 364492 R 486410 CDS YP_002996106.1 251781804 8110878 complement(365176..366552) 1 NC_012891.1 similar to KtrB [Streptococcus pyogenes MGAS10394]; potassium uptake protein 366552 ktrB 8110878 ktrB Streptococcus dysgalactiae subsp. equisimilis GGS_124 potassium uptake protein YP_002996106.1 365176 R 486410 CDS YP_002996107.1 251781805 8110879 complement(366636..367349) 1 NC_012891.1 glucose-inhibited division protein B; SAM-dependent methyltransferase; methylates the N7 position of guanosine in position 527 of 16S rRNA; 16S rRNA methyltransferase GidB 367349 gidB 8110879 gidB Streptococcus dysgalactiae subsp. equisimilis GGS_124 16S rRNA methyltransferase GidB YP_002996107.1 366636 R 486410 CDS YP_002996108.1 251781806 8111993 367502..368059 1 NC_012891.1 similar to LemA [Streptococcus pyogenes MGAS10394]; cytoplasmic membrane protein 368059 lemA 8111993 lemA Streptococcus dysgalactiae subsp. equisimilis GGS_124 cytoplasmic membrane protein YP_002996108.1 367502 D 486410 CDS YP_002996109.1 251781807 8110891 368106..368999 1 NC_012891.1 metalloprotease; heat shock protein HtpX 368999 8110891 SDEG_0393 Streptococcus dysgalactiae subsp. equisimilis GGS_124 heat shock protein HtpX YP_002996109.1 368106 D 486410 CDS YP_002996110.1 251781808 8112075 369263..369799 1 NC_012891.1 similar to hypothetical cytosolic protein [Streptococcus pyogenes MGAS10394]; hypothetical protein 369799 8112075 SDEG_0394 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996110.1 369263 D 486410 CDS YP_002996111.1 251781809 8112076 370069..370755 1 NC_012891.1 similar to response regulator CsrR [Streptococcus pyogenes MGAS10394]; response regulator 370755 covR 8112076 covR Streptococcus dysgalactiae subsp. equisimilis GGS_124 response regulator YP_002996111.1 370069 D 486410 CDS YP_002996112.1 251781810 8111643 370761..372260 1 NC_012891.1 similar to transmembrane histidine kinase CsrS [Streptococcus pyogenes MGAS10394]; transmembrane histidine kinase 372260 covS 8111643 covS Streptococcus dysgalactiae subsp. equisimilis GGS_124 transmembrane histidine kinase YP_002996112.1 370761 D 486410 CDS YP_002996113.1 251781811 8111644 372466..372960 1 NC_012891.1 similar to ribonucleotide reductase NrdR family transcriptional regulator [Streptococcus equi subsp. zooepidemicus MGCS10565]; NrdR family transcriptional regulator 372960 nrdR 8111644 nrdR Streptococcus dysgalactiae subsp. equisimilis GGS_124 NrdR family transcriptional regulator YP_002996113.1 372466 D 486410 CDS YP_002996114.1 251781812 8111723 372944..374122 1 NC_012891.1 replication initiation/membrane attachment protein[DNA replication recombination and repair]; COG3611; similar to replicative DNA helicase [Streptococcus pyogenes MGAS6180]; replicative DNA helicase 374122 dnaB 8111723 dnaB Streptococcus dysgalactiae subsp. equisimilis GGS_124 replicative DNA helicase YP_002996114.1 372944 D 486410 CDS YP_002996115.1 251781813 8111843 374123..375025 1 NC_012891.1 Primosomal protein that may act to load helicase DnaC during DNA replication; primosomal protein DnaI 375025 dnaI 8111843 dnaI Streptococcus dysgalactiae subsp. equisimilis GGS_124 primosomal protein DnaI YP_002996115.1 374123 D 486410 CDS YP_002996116.1 251781814 8111847 375088..376398 1 NC_012891.1 EngA; essential Neisserial GTPase; synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains; GTP-binding protein EngA 376398 engA 8111847 engA Streptococcus dysgalactiae subsp. equisimilis GGS_124 GTP-binding protein EngA YP_002996116.1 375088 D 486410 CDS YP_002996117.1 251781815 8111870 376615..379713 1 NC_012891.1 similar to SWF/SNF family helicase [Streptococcus pyogenes MGAS10394]; SWF/SNF family helicase 379713 snf 8111870 snf Streptococcus dysgalactiae subsp. equisimilis GGS_124 SWF/SNF family helicase YP_002996117.1 376615 D 486410 CDS YP_002996118.1 251781816 8110493 379954..380559 1 NC_012891.1 similar to hypothetical protein spyM18 0396 [Streptococcus pyogenes MGAS8232]; hypothetical protein 380559 8110493 SDEG_0402 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996118.1 379954 D 486410 CDS YP_002996119.1 251781817 8112077 380603..381934 1 NC_012891.1 Catalyzes the formation of UDP-N-acetylmuramoyl-L-alanine from UDP-N-acetylmuramate and L-alanine in peptidoglycan synthesis; UDP-N-acetylmuramate--L-alanine ligase 381934 murC 8112077 murC Streptococcus dysgalactiae subsp. equisimilis GGS_124 UDP-N-acetylmuramate--L-alanine ligase YP_002996119.1 380603 D 486410 CDS YP_002996120.1 251781818 8111684 381978..382463 1 NC_012891.1 similar to arylalkylamine n-acetyltransferase [Streptococcus pyogenes MGAS8232]; arylalkylamine n-acetyltransferase 382463 8111684 SDEG_0404 Streptococcus dysgalactiae subsp. equisimilis GGS_124 arylalkylamine n-acetyltransferase YP_002996120.1 381978 D 486410 CDS YP_002996121.1 251781819 8112078 382575..384182 1 NC_012891.1 similar to aminodeoxychorismate lyase family [Streptococcus pyogenes MGAS10394]; aminodeoxychorismate lyase family 384182 8112078 SDEG_0405 Streptococcus dysgalactiae subsp. equisimilis GGS_124 aminodeoxychorismate lyase family YP_002996121.1 382575 D 486410 CDS YP_002996122.1 251781820 8112079 384255..384737 1 NC_012891.1 necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus; transcription elongation factor GreA 384737 greA 8112079 greA Streptococcus dysgalactiae subsp. equisimilis GGS_124 transcription elongation factor GreA YP_002996122.1 384255 D 486410 CDS YP_002996123.1 251781821 8112018 complement(384947..385870) 1 NC_012891.1 involved in biogenesis of membrane proteins; Firmicutes specific proteins are shorter than other bacterial counterparts and have a signal peptide and lipid attachment site; OxaA-like protein 385870 8112018 SDEG_0407 Streptococcus dysgalactiae subsp. equisimilis GGS_124 OxaA-like protein YP_002996123.1 384947 R 486410 CDS YP_002996124.1 251781822 8112080 complement(385953..386264) 1 NC_012891.1 catalyzes the hydrolysis of acylphosphate; acylphosphatase 386264 8112080 SDEG_0408 Streptococcus dysgalactiae subsp. equisimilis GGS_124 acylphosphatase YP_002996124.1 385953 R 486410 CDS YP_002996125.1 251781823 8112081 386494..387231 1 NC_012891.1 similar to 23S rRNA methyltransferase [Streptococcus pyogenes MGAS10394]; 23S rRNA methyltransferase 387231 8112081 SDEG_0409 Streptococcus dysgalactiae subsp. equisimilis GGS_124 23S rRNA methyltransferase YP_002996125.1 386494 D 486410 CDS YP_002996126.1 251781824 8112082 387270..387770 1 NC_012891.1 similar to hydrolase (HAD superfamily) [Streptococcus pyogenes MGAS10394]; HAD superfamily hydrolase 387770 8112082 SDEG_0410 Streptococcus dysgalactiae subsp. equisimilis GGS_124 HAD superfamily hydrolase YP_002996126.1 387270 D 486410 CDS YP_002996127.1 251781825 8112083 387785..388474 1 NC_012891.1 similar to integral membrane protein [Streptococcus pyogenes MGAS10394]; integral membrane protein 388474 8112083 SDEG_0411 Streptococcus dysgalactiae subsp. equisimilis GGS_124 integral membrane protein YP_002996127.1 387785 D 486410 CDS YP_002996128.1 251781826 8112084 389002..389244 1 NC_012891.1 similar to hypothetical protein M6 Spy0328 [Streptococcus pyogenes MGAS10394]; hypothetical protein 389244 8112084 SDEG_0412 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996128.1 389002 D 486410 CDS YP_002996129.1 251781827 8112085 389421..390218 1 NC_012891.1 converts L-glutamate to D-glutamate, a component of peptidoglycan; glutamate racemase 390218 glr 8112085 glr Streptococcus dysgalactiae subsp. equisimilis GGS_124 glutamate racemase YP_002996129.1 389421 D 486410 CDS YP_002996130.1 251781828 8112010 390176..391201 1 NC_012891.1 HAM1-like protein; Rec-dependent growth; RgdB; yggV; it is suspected that this protein functions to remove misincorporated bases such as xanthine or hypoxanthine; deoxyribonucleotide triphosphate pyrophosphatase/hypothetical protein 391201 8112010 SDEG_0414 Streptococcus dysgalactiae subsp. equisimilis GGS_124 deoxyribonucleotide triphosphate pyrophosphatase/hypothetical protein YP_002996130.1 390176 D 486410 CDS YP_002996131.1 251781829 8112086 391180..391701 1 NC_012891.1 similar to hypothetical protein spyM18 0413 [Streptococcus pyogenes MGAS8232]; hypothetical protein 391701 8112086 SDEG_0415 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996131.1 391180 D 486410 CDS YP_002996132.1 251781830 8112087 391698..392159 1 NC_012891.1 similar to hypothetical protein [Streptococcus pyogenes MGAS5005]; hypothetical protein 392159 8112087 SDEG_0416 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996132.1 391698 D 486410 CDS YP_002996133.1 251781831 8112088 392156..392902 1 NC_012891.1 site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs; site-specific tyrosine recombinase XerD 392902 xerD 8112088 xerD Streptococcus dysgalactiae subsp. equisimilis GGS_124 site-specific tyrosine recombinase XerD YP_002996133.1 392156 D 486410 CDS YP_002996134.1 251781832 8112089 392902..393609 1 NC_012891.1 functions during chromosome segregation; may form a condensin-like structure with SMC and ScpB; segregation and condensation protein A 393609 scpA 8112089 scpA Streptococcus dysgalactiae subsp. equisimilis GGS_124 segregation and condensation protein A YP_002996134.1 392902 D 486410 CDS YP_002996135.1 251781833 8110466 393606..394169 1 NC_012891.1 functions during chromosome segregation; may form a condensin-like structure with SMC and ScpA; forms a homodimer; segregation and condensation protein B 394169 scpB 8110466 scpB Streptococcus dysgalactiae subsp. equisimilis GGS_124 segregation and condensation protein B YP_002996135.1 393606 D 486410 CDS YP_002996136.1 251781834 8110467 394278..395000 1 NC_012891.1 similar to Ribosomal large subunit pseudouridine synthase B [Streptococcus pyogenes MGAS10394]; ribosomal large subunit pseudouridine synthase B 395000 8110467 SDEG_0420 Streptococcus dysgalactiae subsp. equisimilis GGS_124 ribosomal large subunit pseudouridine synthase B YP_002996136.1 394278 D 486410 CDS YP_002996137.1 251781835 8112090 394997..395248 1 NC_012891.1 similar to hypothetical protein Sez 1639 [Streptococcus equi subsp. zooepidemicus MGCS10565]; hypothetical protein 395248 8112090 SDEG_0421 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996137.1 394997 D 486410 CDS YP_002996138.1 251781836 8112091 395389..395985 1 NC_012891.1 similar to 23S rRNA methyltransferase [Streptococcus pyogenes MGAS10394]; tRNA (cytosine34-2'-O-)-methyltransferase 395985 8112091 SDEG_0422 Streptococcus dysgalactiae subsp. equisimilis GGS_124 tRNA (cytosine34-2'-O-)-methyltransferase YP_002996138.1 395389 D 486410 CDS YP_002996139.1 251781837 8112092 396540..397103 1 NC_012891.1 similar to hypothetical protein spyM18 0427 [Streptococcus pyogenes MGAS8232]; hypothetical protein 397103 8112092 SDEG_0423 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996139.1 396540 D 486410 CDS YP_002996140.1 251781838 8112093 397108..397758 1 NC_012891.1 similar to phosphatidylglycerophosphatase B homolog [Streptococcus pyogenes MGAS5005]; phosphatidylglycerophosphatase B 397758 8112093 SDEG_0424 Streptococcus dysgalactiae subsp. equisimilis GGS_124 phosphatidylglycerophosphatase B YP_002996140.1 397108 D 486410 CDS YP_002996141.1 251781839 8112094 397935..398876 1 NC_012891.1 similar to Fe-S oxidoreductase [Streptococcus pyogenes MGAS10394]; Fe-S oxidoreductase 398876 8112094 SDEG_0425 Streptococcus dysgalactiae subsp. equisimilis GGS_124 Fe-S oxidoreductase YP_002996141.1 397935 D 486410 CDS YP_002996142.1 251781840 8112095 398899..399453 1 NC_012891.1 similar to SAM-dependent methyltransferase [Streptococcus pyogenes M1 GAS]; SAM-dependent methyltransferase 399453 8112095 SDEG_0426 Streptococcus dysgalactiae subsp. equisimilis GGS_124 SAM-dependent methyltransferase YP_002996142.1 398899 D 486410 CDS YP_002996143.1 251781841 8112096 399573..400907 1 NC_012891.1 similar to hemolysin [Streptococcus pyogenes MGAS8232]; hemolysin 400907 8112096 SDEG_0427 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hemolysin YP_002996143.1 399573 D 486410 CDS YP_002996144.1 251781842 8112097 400913..401776 1 NC_012891.1 similar to pyruvate formate-lyase activating enzyme [Streptococcus pyogenes MGAS10394]; pyruvate formate-lyase activating enzyme 401776 8112097 SDEG_0428 Streptococcus dysgalactiae subsp. equisimilis GGS_124 pyruvate formate-lyase activating enzyme YP_002996144.1 400913 D 486410 CDS YP_002996145.1 251781843 8112098 401906..402841 1 NC_012891.1 catalyzes the hydrolysis of pyrophosphate to phosphate; manganese-dependent inorganic pyrophosphatase 402841 8112098 SDEG_0429 Streptococcus dysgalactiae subsp. equisimilis GGS_124 manganese-dependent inorganic pyrophosphatase YP_002996145.1 401906 D 486410 CDS YP_002996146.1 251781844 8112099 402841..403569 1 NC_012891.1 similar to hypothetical cytosolic protein [Streptococcus pyogenes MGAS10394]; hypothetical protein 403569 8112099 SDEG_0430 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996146.1 402841 D 486410 CDS YP_002996147.1 251781845 8112100 complement(403614..404615) 1 NC_012891.1 similar to ferrichrome transport system permease protein [Streptococcus pyogenes MGAS5005]; ferrichrome transport system permease 404615 fhuG 8112100 fhuG Streptococcus dysgalactiae subsp. equisimilis GGS_124 ferrichrome transport system permease YP_002996147.1 403614 R 486410 CDS YP_002996148.1 251781846 8111897 complement(404612..405655) 1 NC_012891.1 similar to ferrichrome transport system permease protein [Streptococcus pyogenes MGAS5005]; ferrichrome transport system permease 405655 fhuB 8111897 fhuB Streptococcus dysgalactiae subsp. equisimilis GGS_124 ferrichrome transport system permease YP_002996148.1 404612 R 486410 CDS YP_002996149.1 251781847 8111893 complement(405648..406586) 1 NC_012891.1 similar to ferrichrome-binding protein [Streptococcus pyogenes MGAS5005]; ferrichrome-binding protein 406586 fhuD 8111893 fhuD Streptococcus dysgalactiae subsp. equisimilis GGS_124 ferrichrome-binding protein YP_002996149.1 405648 R 486410 CDS YP_002996150.1 251781848 8111896 complement(406611..407393) 1 NC_012891.1 similar to ferrichrome transport ATP-binding protein [Streptococcus pyogenes MGAS5005]; ferrichrome transport ATP-binding protein 407393 fhuA 8111896 fhuA Streptococcus dysgalactiae subsp. equisimilis GGS_124 ferrichrome transport ATP-binding protein YP_002996150.1 406611 R 486410 CDS YP_002996151.1 251781849 8111892 complement(407642..409087) 1 NC_012891.1 involved in cell wall formation; peptidoglycan synthesis; cytoplasmic enzyme; catalyzes the addition of lysine to UDP-N-acetylmuramoyl-L-alanyl-D-glutamate forming UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysine; UDP-N-acetylmuramoylalanyl-D-glutamate--L-lysine ligase 409087 murE 8111892 murE Streptococcus dysgalactiae subsp. equisimilis GGS_124 UDP-N-acetylmuramoylalanyl-D-glutamate--L-lysine ligase YP_002996151.1 407642 R 486410 CDS YP_002996152.1 251781850 8111686 409175..410809 1 NC_012891.1 similar to export protein for polysaccharides and teichoic acids [Streptococcus pyogenes MGAS5005]; polysaccharides and teichoicacids export protein 410809 8111686 SDEG_0436 Streptococcus dysgalactiae subsp. equisimilis GGS_124 polysaccharides and teichoicacids export protein YP_002996152.1 409175 D 486410 CDS YP_002996153.1 251781851 8112101 complement(410795..411880) 1 NC_012891.1 similar to transposase [Streptococcus pyogenes MGAS10394]; transposase 411880 8112101 SDEG_0437 Streptococcus dysgalactiae subsp. equisimilis GGS_124 transposase YP_002996153.1 410795 R 486410 CDS YP_002996154.1 251781852 8112102 412094..412723 1 NC_012891.1 Catalyzes the formation of uracil and 5-phospho-alpha-D-ribosy 1-diphosphate from UMP and diphosphate; uracil phosphoribosyltransferase 412723 upp 8112102 upp Streptococcus dysgalactiae subsp. equisimilis GGS_124 uracil phosphoribosyltransferase YP_002996154.1 412094 D 486410 CDS YP_002996155.1 251781853 8111943 412945..413535 1 NC_012891.1 hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates; ATP-dependent Clp protease proteolytic subunit 413535 clpP 8111943 clpP Streptococcus dysgalactiae subsp. equisimilis GGS_124 ATP-dependent Clp protease proteolytic subunit YP_002996155.1 412945 D 486410 CDS YP_002996156.1 251781854 8111624 413921..414217 1 NC_012891.1 similar to hypothetical protein gbs2095 [Streptococcus agalactiae NEM316]; hypothetical protein 414217 8111624 SDEG_0440 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996156.1 413921 D 486410 CDS YP_002996157.1 251781855 8112103 414292..414762 1 NC_012891.1 similar to hypothetical proteinSMU.1671c [Streptococcus mutans UA159]; hypothetical protein 414762 8112103 SDEG_0441 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996157.1 414292 D 486410 CDS YP_002996158.1 251781856 8112104 414738..415028 1 NC_012891.1 similar to conserved hypothetical protein [Streptococcus pyogenes M1GAS]; hypothetical protein 415028 8112104 SDEG_0442 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996158.1 414738 D 486410 CDS YP_002996159.1 251781857 8112105 415232..416404 1 NC_012891.1 similar to ABC transporter, branched chain amino acid-binding protein [Streptococcus mutans UA159]; branched-chain amino acid ABC transporter substrate-binding protein 416404 livK 8112105 livK Streptococcus dysgalactiae subsp. equisimilis GGS_124 branched-chain amino acid ABC transporter substrate-binding protein YP_002996159.1 415232 D 486410 CDS YP_002996160.1 251781858 8110899 416593..417462 1 NC_012891.1 similar to branched chain amino acid ABC transporter, permease protein [Streptococcus mutans UA159]; branched-chain amino acid ABC transporter permease 417462 livH 8110899 livH Streptococcus dysgalactiae subsp. equisimilis GGS_124 branched-chain amino acid ABC transporter permease YP_002996160.1 416593 D 486410 CDS YP_002996161.1 251781859 8110898 417466..418419 1 NC_012891.1 similar to branched chain amino acid ABC transporter, permease protein [Streptococcus mutans UA159]; branched-chain amino acid ABC transporter permease 418419 livM 8110898 livM Streptococcus dysgalactiae subsp. equisimilis GGS_124 branched-chain amino acid ABC transporter permease YP_002996161.1 417466 D 486410 CDS YP_002996162.1 251781860 8110900 418420..419184 1 NC_012891.1 similar to branched-chain amino acid ABC transporter ATP binding protein [Streptococcus thermophilus CNRZ1066]; branched-chain amino acid ABC transporter ATP binding protein 419184 livG 8110900 livG Streptococcus dysgalactiae subsp. equisimilis GGS_124 branched-chain amino acid ABC transporter ATP binding protein YP_002996162.1 418420 D 486410 CDS YP_002996163.1 251781861 8110897 419184..419894 1 NC_012891.1 similar to ABC-type branched-chain amino acid transport system ATPase component [Streptococcus suis 98HAH33]; branched-chain amino acid ABC transporter ATPase 419894 livF 8110897 livF Streptococcus dysgalactiae subsp. equisimilis GGS_124 branched-chain amino acid ABC transporter ATPase YP_002996163.1 419184 D 486410 CDS YP_002996164.1 251781862 8110896 419939..420601 1 NC_012891.1 similar to hypothetical protein STRINF 01997 [Streptococcus infantarius subsp. infantarius ATCC BAA-102]; hypothetical protein 420601 8110896 SDEG_0448 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996164.1 419939 D 486410 CDS YP_002996165.1 251781863 8112106 420688..421323 1 NC_012891.1 catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to thymidine monophosphate (dTMP) to form thymidine diphosphate (dTDP); thymidylate kinase 421323 tmk 8112106 tmk Streptococcus dysgalactiae subsp. equisimilis GGS_124 thymidylate kinase YP_002996165.1 420688 D 486410 CDS YP_002996166.1 251781864 8110526 421339..422211 1 NC_012891.1 catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the delta' subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA.; DNA polymerase III subunit delta' 422211 8110526 SDEG_0450 Streptococcus dysgalactiae subsp. equisimilis GGS_124 DNA polymerase III subunit delta' YP_002996166.1 421339 D 486410 CDS YP_002996167.1 251781865 8112107 422208..423008 1 NC_012891.1 similar to DNA replicationintiation control protein YabA [Streptococcus pyogenes M1GAS]; Involved in initiation control of chromosomereplication.; initiation-control protein, YabA-like 423008 yabA 8112107 yabA Streptococcus dysgalactiae subsp. equisimilis GGS_124 initiation-control protein, YabA-like YP_002996167.1 422208 D 486410 CDS YP_002996168.1 251781866 8111957 423001..423324 1 NC_012891.1 in Bacillus subtilis this protein is involved in the negative regulation of DNA replication initiation; interacts with DnaN and DnaA; DNA replication intiation control protein YabA 423324 8111957 SDEG_0452 Streptococcus dysgalactiae subsp. equisimilis GGS_124 DNA replication intiation control protein YabA YP_002996168.1 423001 D 486410 CDS YP_002996169.1 251781867 8112108 423329..424192 1 NC_012891.1 similar to corrin /porphyrin methyltransferase [Streptococcus pyogenes MGAS6180]; corrin/porphyrin methyltransferase 424192 8112108 SDEG_0453 Streptococcus dysgalactiae subsp. equisimilis GGS_124 corrin/porphyrin methyltransferase YP_002996169.1 423329 D 486410 CDS YP_002996170.1 251781868 8112109 424219..424611 1 NC_012891.1 similar to hypothetical membrane associated protein [Streptococcus pyogenes MGAS5005]; hypothetical protein 424611 8112109 SDEG_0454 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996170.1 424219 D 486410 CDS YP_002996171.1 251781869 8112110 complement(424658..425287) 1 NC_012891.1 similar to copper homeostasis protein [Streptococcus pyogenes MGAS6180]; copper homeostasis protein 425287 cutC 8112110 cutC Streptococcus dysgalactiae subsp. equisimilis GGS_124 copper homeostasis protein YP_002996171.1 424658 R 486410 CDS YP_002996172.1 251781870 8111654 425404..426495 1 NC_012891.1 catalyzes the formation of 3-phosphonooxypyruvate and glutamate from O-phospho-L-serine and 2-oxoglutarate; required both in major phosphorylated pathway of serine biosynthesis and in the biosynthesis of pyridoxine; phosphoserine aminotransferase 426495 8111654 SDEG_0456 Streptococcus dysgalactiae subsp. equisimilis GGS_124 phosphoserine aminotransferase YP_002996172.1 425404 D 486410 CDS YP_002996173.1 251781871 8112111 426521..427072 1 NC_012891.1 similar to acetyltransferase [Streptococcus equi]; GNAT family acetyltransferase 427072 8112111 SDEG_0457 Streptococcus dysgalactiae subsp. equisimilis GGS_124 GNAT family acetyltransferase YP_002996173.1 426521 D 486410 CDS YP_002996174.1 251781872 8112112 427133..427630 1 NC_012891.1 similar to methylated-DNA-protein-cysteine S-methyltransferase[Streptococcus mutans UA159]; methylated-DNA-protein- cysteinemethyltransferase 427630 ogt 8112112 ogt Streptococcus dysgalactiae subsp. equisimilis GGS_124 methylated-DNA-protein- cysteinemethyltransferase YP_002996174.1 427133 D 486410 CDS YP_002996175.1 251781873 8111732 427627..427983 1 NC_012891.1 similar to arsenate reductase family protein [Streptococcus pyogenes MGAS10270]; arsenate reductase 427983 8111732 SDEG_0459 Streptococcus dysgalactiae subsp. equisimilis GGS_124 arsenate reductase YP_002996175.1 427627 D 486410 CDS YP_002996176.1 251781874 8112113 complement(428034..428342) 1 NC_012891.1 similar to hypothetical protein SAG1540 [Streptococcus agalactiae 2603V/R]; hypothetical protein 428342 8112113 SDEG_0460 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996176.1 428034 R 486410 CDS YP_002996177.1 251781875 8112114 complement(428344..428733) 1 NC_012891.1 similar to glyoxalase family protein [Streptococcus agalactiae 2603V/R]; glyoxalase 428733 8112114 SDEG_0461 Streptococcus dysgalactiae subsp. equisimilis GGS_124 glyoxalase YP_002996177.1 428344 R 486410 CDS YP_002996178.1 251781876 8112115 complement(428831..429766) 1 NC_012891.1 similar to sugar-binding transcriptional regulator; LacI family transcriptional regulator 429766 8112115 SDEG_0462 Streptococcus dysgalactiae subsp. equisimilis GGS_124 LacI family transcriptional regulator YP_002996178.1 428831 R 486410 CDS YP_002996179.1 251781877 8112116 complement(429763..430575) 1 NC_012891.1 similar to HAD superfamily hydrolase [Streptococcus agalactiae 2603V/R]; haloacid dehalogenase family hydrolase 430575 8112116 SDEG_0463 Streptococcus dysgalactiae subsp. equisimilis GGS_124 haloacid dehalogenase family hydrolase YP_002996179.1 429763 R 486410 CDS YP_002996180.1 251781878 8112117 complement(430704..431531) 1 NC_012891.1 similar to 3'-exo-deoxyribonuclease [Streptococcus pyogenes M1 GAS]; 3'-exo-deoxyribonuclease 431531 exoA 8112117 exoA Streptococcus dysgalactiae subsp. equisimilis GGS_124 3'-exo-deoxyribonuclease YP_002996180.1 430704 R 486410 CDS YP_002996181.1 251781879 8111874 431820..432452 1 NC_012891.1 similar to hemolysis inducing protein [Streptococcus mutans UA159]; hypothetical protein 432452 8111874 SDEG_0465 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996181.1 431820 D 486410 CDS YP_002996182.1 251781880 8112118 432751..434280 1 NC_012891.1 similar to L-lactate permease; L-lactate permease 434280 lctP 8112118 lctP Streptococcus dysgalactiae subsp. equisimilis GGS_124 L-lactate permease YP_002996182.1 432751 D 486410 CDS YP_002996183.1 251781881 8110889 434422..435603 1 NC_012891.1 similar to lactate oxidase [Streptococcus pyogenes MGAS8232]; lactate oxidase 435603 8110889 SDEG_0467 Streptococcus dysgalactiae subsp. equisimilis GGS_124 lactate oxidase YP_002996183.1 434422 D 486410 CDS YP_002996184.1 251781882 8112119 435855..437222 1 NC_012891.1 similar to cell envelope proteinase A [Streptococcus pyogenes]; cell envelope proteinase A 437222 cepA 8112119 cepA Streptococcus dysgalactiae subsp. equisimilis GGS_124 cell envelope proteinase A YP_002996184.1 435855 D 486410 CDS YP_002996185.1 251781883 8111611 437173..438603 1 NC_012891.1 similar to cell envelope proteinase A [Streptococcus pyogenes]; cell envelope proteinase A 438603 cepA 8111611 cepA Streptococcus dysgalactiae subsp. equisimilis GGS_124 cell envelope proteinase A YP_002996185.1 437173 D 486410 CDS YP_002996186.1 251781884 8111612 438674..440605 1 NC_012891.1 similar to cell envelope proteinase A [Streptococcus pyogenes]; cell envelope proteinase A 440605 cepA 8111612 cepA Streptococcus dysgalactiae subsp. equisimilis GGS_124 cell envelope proteinase A YP_002996186.1 438674 D 486410 CDS YP_002996187.1 251781885 8111613 440818..442482 1 NC_012891.1 similar to conserved hypothetical protein [Streptococcus suis 89/1591]; cell shape-determining protein 442482 8111613 SDEG_0471 Streptococcus dysgalactiae subsp. equisimilis GGS_124 cell shape-determining protein YP_002996187.1 440818 D 486410 CDS YP_002996188.1 251781886 8112120 442767..443474 1 NC_012891.1 similar to hypothetical membrane spanning protein [Streptococcus pyogenes MGAS2096]; hypothetical protein 443474 8112120 SDEG_0472 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996188.1 442767 D 486410 CDS YP_002996189.1 251781887 8112121 443739..445739 1 NC_012891.1 methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content; methionyl-tRNA synthetase 445739 metS 8112121 metS Streptococcus dysgalactiae subsp. equisimilis GGS_124 methionyl-tRNA synthetase YP_002996189.1 443739 D 486410 CDS YP_002996190.1 251781888 8110936 446272..447285 1 NC_012891.1 similar to ribonucleoside-diphosphate reductase beta chain [Streptococcus pyogenes MGAS2096]; ribonucleotide-diphosphate reductase subunit beta 447285 nrdF1 8110936 nrdF1 Streptococcus dysgalactiae subsp. equisimilis GGS_124 ribonucleotide-diphosphate reductase subunit beta YP_002996190.1 446272 D 486410 CDS YP_002996191.1 251781889 8111719 447289..447762 1 NC_012891.1 in Salmonella NrdI has a stimulatory effect on the ribonucleotide reductase activity of NrdH with NrdEF; ribonucleotide reductase stimulatory protein 447762 nrdI 8111719 nrdI Streptococcus dysgalactiae subsp. equisimilis GGS_124 ribonucleotide reductase stimulatory protein YP_002996191.1 447289 D 486410 CDS YP_002996192.1 251781890 8111722 447746..449932 1 NC_012891.1 Catalyzes the rate-limiting step in dNTP synthesis; ribonucleotide-diphosphate reductase subunit alpha 449932 nrdE1 8111722 nrdE1 Streptococcus dysgalactiae subsp. equisimilis GGS_124 ribonucleotide-diphosphate reductase subunit alpha YP_002996192.1 447746 D 486410 CDS YP_002996193.1 251781891 8111717 450230..451564 1 NC_012891.1 similar to branched-chain amino acid transport system II carrier protein [Streptococcus agalactiae 2603V/R]; branched-chain amino acid transport system II carrier protein 451564 brnQ-1 8111717 brnQ-1 Streptococcus dysgalactiae subsp. equisimilis GGS_124 branched-chain amino acid transport system II carrier protein YP_002996193.1 450230 D 486410 CDS YP_002996194.1 251781892 8111598 complement(451902..452765) 1 NC_012891.1 similar to transposase [Streptococcus pyogenes MGAS2096]; transposase 452765 8111598 SDEG_0478 Streptococcus dysgalactiae subsp. equisimilis GGS_124 transposase YP_002996194.1 451902 R 486410 CDS YP_002996195.1 251781893 8112122 453629..453865 1 NC_012891.1 similar to hypothetical protein spr0700 [Streptococcus pneumoniae R6]; hypothetical protein 453865 8112122 SDEG_0479 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996195.1 453629 D 486410 CDS YP_002996196.1 251781894 8112123 453858..454556 1 NC_012891.1 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis; 3-ketoacyl-ACP reductase 454556 fabG 8112123 fabG Streptococcus dysgalactiae subsp. equisimilis GGS_124 3-ketoacyl-ACP reductase YP_002996196.1 453858 D 486410 CDS YP_002996197.1 251781895 8112124 454813..455262 1 NC_012891.1 similar to conserved hypothetical protein [Streptococcus agalactiae H36B]; hypothetical protein 455262 8112124 SDEG_0481 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996197.1 454813 D 486410 CDS YP_002996198.1 251781896 8112125 455264..456223 1 NC_012891.1 similar to hypothetical protein SPs1547 [Streptococcus pyogenes SSI-1]; hypothetical protein 456223 8112125 SDEG_0482 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996198.1 455264 D 486410 CDS YP_002996199.1 251781897 8112126 456557..457894 1 NC_012891.1 similar to phosphoglycerate transporter protein [Streptococcus pyogenes MGAS6180]; phosphoglycerate transporter protein 457894 8112126 SDEG_0483 Streptococcus dysgalactiae subsp. equisimilis GGS_124 phosphoglycerate transporter protein YP_002996199.1 456557 D 486410 CDS YP_002996200.1 251781898 8112127 458066..459448 1 NC_012891.1 forms a homotrimer; catalyzes the acetylation of glucosamine-1-phosphate and uridylation of N-acetylglucosamine-1-phosphate to produce UDP-GlcNAc; function in cell wall synthesis; bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase 459448 glmU 8112127 glmU Streptococcus dysgalactiae subsp. equisimilis GGS_124 bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase YP_002996200.1 458066 D 486410 CDS YP_002996201.1 251781899 8111989 459479..460033 1 NC_012891.1 similar to ADP-ribose pyrophosphatase [Streptococcus pyogenes MGAS10750]; ADP-ribose pyrophosphatase 460033 8111989 SDEG_0485 Streptococcus dysgalactiae subsp. equisimilis GGS_124 ADP-ribose pyrophosphatase YP_002996201.1 459479 D 486410 CDS YP_002996202.1 251781900 8112128 460303..460998 1 NC_012891.1 enables the cleavage of the glycosidic bond in both 5'-methylthioadenosine and S-adenosylhomocysteine; 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase 460998 mtnN 8112128 mtnN Streptococcus dysgalactiae subsp. equisimilis GGS_124 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase YP_002996202.1 460303 D 486410 CDS YP_002996203.1 251781901 8110947 complement(461071..461718) 1 NC_012891.1 similar to iron-dependent repressor [Streptococcus pyogenes MGAS6180]; iron-dependent repressor 461718 scaR 8110947 scaR Streptococcus dysgalactiae subsp. equisimilis GGS_124 iron-dependent repressor YP_002996203.1 461071 R 486410 CDS YP_002996204.1 251781902 8110464 461864..462796 1 NC_012891.1 similar to manganese-binding protein [Streptococcus pyogenes MGAS5005]; manganese-binding protein 462796 mtsA 8110464 mtsA Streptococcus dysgalactiae subsp. equisimilis GGS_124 manganese-binding protein YP_002996204.1 461864 D 486410 CDS YP_002996205.1 251781903 8110948 462861..463586 1 NC_012891.1 similar to manganese transport system ATP-binding protein [Streptococcus pyogenes MGAS5005]; manganese transport system ATP-binding protein 463586 mtsB 8110948 mtsB Streptococcus dysgalactiae subsp. equisimilis GGS_124 manganese transport system ATP-binding protein YP_002996205.1 462861 D 486410 CDS YP_002996206.1 251781904 8111678 463587..464435 1 NC_012891.1 similar to metal cation ABC transporter membrane protein [Streptococcus pyogenes str. Manfredo]; metal cation ABC transporter membrane protein 464435 mtsC 8111678 mtsC Streptococcus dysgalactiae subsp. equisimilis GGS_124 metal cation ABC transporter membrane protein YP_002996206.1 463587 D 486410 CDS YP_002996207.1 251781905 8111679 complement(464566..465372) 1 NC_012891.1 similar to peptidyl-prolyl cis-trans isomerase [Streptococcus pyogenes MGAS5005]; peptidyl-prolyl cis-trans isomerase 465372 8111679 SDEG_0491 Streptococcus dysgalactiae subsp. equisimilis GGS_124 peptidyl-prolyl cis-trans isomerase YP_002996207.1 464566 R 486410 CDS YP_002996208.1 251781906 8112129 465491..467998 1 NC_012891.1 similar to cell division protein [Streptococcus pyogenes MGAS5005]; cell division protein 467998 ftsK 8112129 ftsK Streptococcus dysgalactiae subsp. equisimilis GGS_124 cell division protein YP_002996208.1 465491 D 486410 CDS YP_002996209.1 251781907 8111919 complement(468067..468420) 1 NC_012891.1 similar to integral membrane protein [Streptococcus pyogenes MGAS5005]; integral membrane protein 468420 8111919 SDEG_0493 Streptococcus dysgalactiae subsp. equisimilis GGS_124 integral membrane protein YP_002996209.1 468067 R 486410 CDS YP_002996210.1 251781908 8112130 complement(468576..469604) 1 NC_012891.1 similar to transposase [Streptococcus pyogenes MGAS10270]; transposase 469604 8112130 SDEG_0494 Streptococcus dysgalactiae subsp. equisimilis GGS_124 transposase YP_002996210.1 468576 R 486410 CDS YP_002996211.1 251781909 8112131 469762..470265 1 NC_012891.1 binds directly to 23S ribosomal RNA; 50S ribosomal protein L11 470265 rplK 8112131 rplK Streptococcus dysgalactiae subsp. equisimilis GGS_124 50S ribosomal protein L11 YP_002996211.1 469762 D 486410 CDS YP_002996212.1 251781910 8111066 470371..471060 1 NC_012891.1 in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA; 50S ribosomal protein L1 471060 rplA 8111066 rplA Streptococcus dysgalactiae subsp. equisimilis GGS_124 50S ribosomal protein L1 YP_002996212.1 470371 D 486410 CDS YP_002996213.1 251781911 8111058 471967..472695 1 NC_012891.1 Catalyzes the phosphorylation of UMP to UDP; uridylate kinase 472695 pyrH 8111058 pyrH Streptococcus dysgalactiae subsp. equisimilis GGS_124 uridylate kinase YP_002996213.1 471967 D 486410 CDS YP_002996214.1 251781912 8111344 472724..473281 1 NC_012891.1 Rrf; Frr; ribosome-recycling factor; release factor 4; RF4; recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G; A GTPase-dependent process results in release of 50S from 70S; inhibited by release factor RF-1; essential for viability; structurally similar to tRNAs; ribosome recycling factor 473281 frr 8111344 frr Streptococcus dysgalactiae subsp. equisimilis GGS_124 ribosome recycling factor YP_002996214.1 472724 D 486410 CDS YP_002996215.1 251781913 8111909 473390..474247 1 NC_012891.1 similar to s1 RNA binding domain [Streptococcus pyogenes MGAS5005]; s1 RNA binding domain 474247 8111909 SDEG_0499 Streptococcus dysgalactiae subsp. equisimilis GGS_124 s1 RNA binding domain YP_002996215.1 473390 D 486410 CDS YP_002996216.1 251781914 8112132 474320..474829 1 NC_012891.1 this stereospecific enzymes reduces the S isomer of methionine sulfoxide while MsrB reduces the R form; provides protection against oxidative stress; methionine sulfoxide reductase A 474829 msrA 8112132 msrA Streptococcus dysgalactiae subsp. equisimilis GGS_124 methionine sulfoxide reductase A YP_002996216.1 474320 D 486410 CDS YP_002996217.1 251781915 8110943 474826..475041 1 NC_012891.1 similar to D-alanyl-D-alanine carboxypeptidase [Streptococcus pyogenes MGAS5005]; hypothetical protein 475041 8110943 SDEG_0501 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996217.1 474826 D 486410 CDS YP_002996218.1 251781916 8112133 475200..476396 1 NC_012891.1 similar to surface antigen [Streptococcus pyogenes MGAS5005]; surface antigen 476396 8112133 SDEG_0502 Streptococcus dysgalactiae subsp. equisimilis GGS_124 surface antigen YP_002996218.1 475200 D 486410 CDS YP_002996219.1 251781917 8112134 476620..478479 1 NC_012891.1 in group A Streptococci this protein was found to cross react with anti myosin antibodies and may play a role in rheumatic fever; myosin-cross-reactive antigen 478479 8112134 SDEG_0503 Streptococcus dysgalactiae subsp. equisimilis GGS_124 myosin-cross-reactive antigen YP_002996219.1 476620 D 486410 CDS YP_002996220.1 251781918 8112135 478640..479701 1 NC_012891.1 similar to PhoH protein [Streptococcus pyogenes MGAS5005]; phosphate starvation-induced protein 479701 phoH 8112135 phoH Streptococcus dysgalactiae subsp. equisimilis GGS_124 phosphate starvation-induced protein YP_002996220.1 478640 D 486410 CDS YP_002996221.1 251781919 8111292 479748..480323 1 NC_012891.1 similar to uracil DNA glycosylase superfamily protein [Streptococcus pyogenes MGAS5005]; uracil DNA glycosylase 480323 8111292 SDEG_0505 Streptococcus dysgalactiae subsp. equisimilis GGS_124 uracil DNA glycosylase YP_002996221.1 479748 D 486410 CDS YP_002996222.1 251781920 8110529 480431..480979 1 NC_012891.1 similar to hypothetical protein M5005 Spy 0388 [Streptococcus pyogenes MGAS5005]; metalloprotease 480979 8110529 SDEG_0506 Streptococcus dysgalactiae subsp. equisimilis GGS_124 metalloprotease YP_002996222.1 480431 D 486410 CDS YP_002996223.1 251781921 8110530 480960..481367 1 NC_012891.1 similar to diacylglycerol kinase [Streptococcus pyogenes MGAS5005]; diacylglycerol kinase 481367 dgk 8110530 dgk Streptococcus dysgalactiae subsp. equisimilis GGS_124 diacylglycerol kinase YP_002996223.1 480960 D 486410 CDS YP_002996224.1 251781922 8111671 481488..482384 1 NC_012891.1 Era; Escherichia coli Ras-like protein; Bex; Bacillus Era-complementing segment; essential protein in Escherichia coli that is involved in many cellular processes; GTPase; binds the cell membrane through apparent C-terminal domain; mutants are arrested during the cell cycle; Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome; GTP-binding protein Era 482384 era 8111671 era Streptococcus dysgalactiae subsp. equisimilis GGS_124 GTP-binding protein Era YP_002996224.1 481488 D 486410 CDS YP_002996225.1 251781923 8111872 482571..482924 1 NC_012891.1 similar to phosphohydrolase [Streptococcus pyogenes MGAS10750]; phosphohydrolase 482924 8111872 SDEG_0509 Streptococcus dysgalactiae subsp. equisimilis GGS_124 phosphohydrolase YP_002996225.1 482571 D 486410 CDS YP_002996226.1 251781924 8110531 complement(482707..484113) 1 NC_012891.1 similar to bacteriocin processing peptidase / bacteriocin export ABC transporter [Streptococcus pyogenes MGAS10750]; bacteriocin processing peptidase 484113 8110531 SDEG_0510 Streptococcus dysgalactiae subsp. equisimilis GGS_124 bacteriocin processing peptidase YP_002996226.1 482707 R 486410 CDS YP_002996227.1 251781925 8110532 484417..484644 1 NC_012891.1 similar to hypothetical protein MGAS10750 Spy0398 [Streptococcus pyogenes MGAS10750]; hypothetical protein 484644 8110532 SDEG_0511 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996227.1 484417 D 486410 CDS YP_002996228.1 251781926 8110533 484681..485010 1 NC_012891.1 similar to hypothetical protein MGAS10750 Spy0399 [Streptococcus pyogenes MGAS10750]; hypothetical protein 485010 8110533 SDEG_0512 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996228.1 484681 D 486410 CDS YP_002996229.1 251781927 8110534 485418..485657 1 NC_012891.1 similar to bacteriocin BlpM [Streptococcus pneumoniae SP6-BS73]; bacteriocin BlpM-like 485657 blpM 8110534 blpM Streptococcus dysgalactiae subsp. equisimilis GGS_124 bacteriocin BlpM-like YP_002996229.1 485418 D 486410 CDS YP_002996230.1 251781928 8111597 485795..485995 1 NC_012891.1 similar to bacteriocin Blp [Streptococcus pneumoniae G54]; bacteriocin 485995 blp 8111597 blp Streptococcus dysgalactiae subsp. equisimilis GGS_124 bacteriocin YP_002996230.1 485795 D 486410 CDS YP_002996231.1 251781929 8112378 486540..487289 1 NC_012891.1 similar to response regulator FasA [Streptococcus pyogenes MGAS10750]; response regulator 487289 fasA 8112378 fasA Streptococcus dysgalactiae subsp. equisimilis GGS_124 response regulator YP_002996231.1 486540 D 486410 CDS YP_002996232.1 251781930 8111881 487290..488624 1 NC_012891.1 similar to sensory transduction protein kinase [Streptococcus pyogenes MGAS10750]; sensory transduction protein kinase 488624 8111881 SDEG_0516 Streptococcus dysgalactiae subsp. equisimilis GGS_124 sensory transduction protein kinase YP_002996232.1 487290 D 486410 CDS YP_002996233.1 251781931 8110535 complement(488685..488810) 1 NC_012891.1 similar to hypothetical protein MGAS10750 Spy0405 [Streptococcus pyogenes MGAS10750]; hypothetical protein 488810 8110535 SDEG_0517 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996233.1 488685 R 486410 CDS YP_002996234.1 251781932 8110536 complement(488901..490265) 1 NC_012891.1 similar to SilD [Streptococcus pyogenes]; hypothetical protein 490265 silD 8110536 silD Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996234.1 488901 R 486410 CDS YP_002996235.1 251781933 8110486 complement(490276..492429) 1 NC_012891.1 similar to bacteriocin processing peptidase / bacteriocin export ABC transporter [Streptococcus pyogenes MGAS10750]; bacteriocin processing peptidase 492429 8110486 SDEG_0519 Streptococcus dysgalactiae subsp. equisimilis GGS_124 bacteriocin processing peptidase YP_002996235.1 490276 R 486410 CDS YP_002996236.1 251781934 8110537 492824..493852 1 NC_012891.1 similar to transposase [Streptococcus pyogenes MGAS10270]; transposase 493852 8110537 SDEG_0520 Streptococcus dysgalactiae subsp. equisimilis GGS_124 transposase YP_002996236.1 492824 D 486410 CDS YP_002996237.1 251781935 8110538 494133..494333 1 NC_012891.1 similar to hypothetical membrane associated protein [Streptococcus pyogenes MGAS10270]; hypothetical protein 494333 8110538 SDEG_0521 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996237.1 494133 D 486410 CDS YP_002996238.1 251781936 8110539 494628..494822 1 NC_012891.1 similar to hypothetical protein M6 Spy0424 [Streptococcus pyogenes MGAS10394]; hypothetical protein 494822 8110539 SDEG_0522 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996238.1 494628 D 486410 CDS YP_002996239.1 251781937 8110540 494872..495132 1 NC_012891.1 similar to hypothetical protein SPs1514 [Streptococcus pyogenes SSI-1]; hypothetical protein 495132 8110540 SDEG_0523 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996239.1 494872 D 486410 CDS YP_002996240.1 251781938 8110541 495348..495758 1 NC_012891.1 similar to hypothetical protein MGAS10750 Spy0413 [Streptococcus pyogenes MGAS10750]; hypothetical protein 495758 8110541 SDEG_0524 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996240.1 495348 D 486410 CDS YP_002996241.1 251781939 8110542 complement(495788..495931) 1 NC_012891.1 similar to hypothetical protein M6 Spy0427 [Streptococcus pyogenes MGAS10394]; hypothetical protein 495931 8110542 SDEG_0525 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996241.1 495788 R 486410 CDS YP_002996242.1 251781940 8110543 496274..496504 1 NC_012891.1 similar to CAAX amino terminal protease family protein [Streptococcus agalactiae NEM316]; CAAX amino terminal protease 496504 8110543 SDEG_0526 Streptococcus dysgalactiae subsp. equisimilis GGS_124 CAAX amino terminal protease YP_002996242.1 496274 D 486410 CDS YP_002996243.1 251781941 8110544 496903..497667 1 NC_012891.1 similar to hypothetical protein MGAS2096 Spy0420 [Streptococcus pyogenes MGAS2096]; hypothetical protein 497667 8110544 SDEG_0527 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996243.1 496903 D 486410 CDS YP_002996244.1 251781942 8110545 complement(497689..498717) 1 NC_012891.1 similar to hypothetical protein SAG1491 [Streptococcus agalactiae 2603V/R]; hypothetical protein 498717 8110545 SDEG_0528 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996244.1 497689 R 486410 CDS YP_002996245.1 251781943 8110546 498944..499798 1 NC_012891.1 similar to transcriptional regulator [Streptococcus pyogenes MGAS10750]; transcriptional regulator 499798 mutR 8110546 mutR Streptococcus dysgalactiae subsp. equisimilis GGS_124 transcriptional regulator YP_002996245.1 498944 D 486410 CDS YP_002996246.1 251781944 8111694 499980..500807 1 NC_012891.1 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases; formamidopyrimidine-DNA glycosylase 500807 fpg 8111694 fpg Streptococcus dysgalactiae subsp. equisimilis GGS_124 formamidopyrimidine-DNA glycosylase YP_002996246.1 499980 D 486410 CDS YP_002996247.1 251781945 8111907 500777..501397 1 NC_012891.1 catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; involved in coenzyme A biosynthesis; dephospho-CoA kinase 501397 coaE 8111907 coaE Streptococcus dysgalactiae subsp. equisimilis GGS_124 dephospho-CoA kinase YP_002996247.1 500777 D 486410 CDS YP_002996248.1 251781946 8110547 501858..502559 1 NC_012891.1 similar to ABC transporter ATP binding protein [Streptococcus agalactiae 2603V/R]; ABC transporter ATP-binding protein 502559 8110547 SDEG_0532 Streptococcus dysgalactiae subsp. equisimilis GGS_124 ABC transporter ATP-binding protein YP_002996248.1 501858 D 486410 CDS YP_002996249.1 251781947 8110548 502549..504186 1 NC_012891.1 similar to hypothetical protein SAG1486 [Streptococcus agalactiae 2603V/R]; hypothetical protein 504186 8110548 SDEG_0533 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996249.1 502549 D 486410 CDS YP_002996250.1 251781948 8110549 504296..505798 1 NC_012891.1 similar to ATPase [Streptococcus pyogenes MGAS9429]; ATPase 505798 8110549 SDEG_0534 Streptococcus dysgalactiae subsp. equisimilis GGS_124 ATPase YP_002996250.1 504296 D 486410 CDS YP_002996251.1 251781949 8110550 506058..507179 1 NC_012891.1 similar to multidrug resistance protein B [Streptococcus pyogenes MGAS10394]; multidrug resistance protein B 507179 8110550 SDEG_0535 Streptococcus dysgalactiae subsp. equisimilis GGS_124 multidrug resistance protein B YP_002996251.1 506058 D 486410 CDS YP_002996252.1 251781950 8110551 507176..507322 1 NC_012891.1 in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif; 50S ribosomal protein L33 507322 rpmG 8110551 rpmG Streptococcus dysgalactiae subsp. equisimilis GGS_124 50S ribosomal protein L33 YP_002996252.1 507176 D 486410 CDS YP_002996253.1 251781951 8110552 507368..507604 1 NC_012891.1 similar to translocase [Streptococcus pyogenes MGAS315]; preprotein translocase subunit SecG 507604 secG 8110552 secG Streptococcus dysgalactiae subsp. equisimilis GGS_124 preprotein translocase subunit SecG YP_002996253.1 507368 D 486410 CDS YP_002996254.1 251781952 8110479 507716..510031 1 NC_012891.1 similar to exoribonuclease II [Streptococcus pyogenes MGAS10750]; exoribonuclease II 510031 8110479 SDEG_0538 Streptococcus dysgalactiae subsp. equisimilis GGS_124 exoribonuclease II YP_002996254.1 507716 D 486410 CDS YP_002996255.1 251781953 8110553 510034..510501 1 NC_012891.1 binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation; SsrA-binding protein 510501 smpB 8110553 smpB Streptococcus dysgalactiae subsp. equisimilis GGS_124 SsrA-binding protein YP_002996255.1 510034 D 486410 CDS YP_002996256.1 251781954 8110492 complement(511097..512023) 1 NC_012891.1 similar to sugar transferase [Streptococcus pyogenes MGAS315]; sugar transferase 512023 8110492 SDEG_0540 Streptococcus dysgalactiae subsp. equisimilis GGS_124 sugar transferase YP_002996256.1 511097 R 486410 CDS YP_002996257.1 251781955 8110554 complement(512160..513344) 1 NC_012891.1 similar to phage-encoded extracellular streptodornase D [Streptococcus pyogenes];deoxyribonuclease; streptodornase D type 513344 sdzD 8110554 sdzD Streptococcus dysgalactiae subsp. equisimilis GGS_124 streptodornase D type YP_002996257.1 512160 R 486410 CDS YP_002996258.1 251781956 8110476 complement(513690..514067) 1 NC_012891.1 similar to lactoylglutathione lyase [Streptococcus pyogenes MGAS315]; lactoylglutathione lyase 514067 gloA 8110476 gloA Streptococcus dysgalactiae subsp. equisimilis GGS_124 lactoylglutathione lyase YP_002996258.1 513690 R 486410 CDS YP_002996259.1 251781957 8112006 complement(514077..514742) 1 NC_012891.1 similar to NAD(P)H-flavin oxidoreductase [Streptococcus pyogenes MGAS315]; NAD(P)H-flavin oxidoreductase 514742 8112006 SDEG_0543 Streptococcus dysgalactiae subsp. equisimilis GGS_124 NAD(P)H-flavin oxidoreductase YP_002996259.1 514077 R 486410 CDS YP_002996260.1 251781958 8110555 complement(514786..515871) 1 NC_012891.1 similar to Xaa-Pro dipeptidase [Streptococcus pyogenes MGAS10394]; Xaa-Pro dipeptidase 515871 8110555 SDEG_0544 Streptococcus dysgalactiae subsp. equisimilis GGS_124 Xaa-Pro dipeptidase YP_002996260.1 514786 R 486410 CDS YP_002996261.1 251781959 8110556 516045..517046 1 NC_012891.1 similar to catabolite control protein A [Streptococcus pyogenes MGAS5005]; catabolite control protein A 517046 ccpA 8110556 ccpA Streptococcus dysgalactiae subsp. equisimilis GGS_124 catabolite control protein A YP_002996261.1 516045 D 486410 CDS YP_002996262.1 251781960 8111609 517200..518663 1 NC_012891.1 converts 1,4-alpha-D-glucans to maltodextrin; alpha-amylase 518663 amyS 8111609 amyS Streptococcus dysgalactiae subsp. equisimilis GGS_124 alpha-amylase YP_002996262.1 517200 D 486410 CDS YP_002996263.1 251781961 8112326 518740..519738 1 NC_012891.1 similar to glycosyltransferase [Streptococcus pyogenes MGAS5005]; glycosyltransferase 519738 8112326 SDEG_0547 Streptococcus dysgalactiae subsp. equisimilis GGS_124 glycosyltransferase YP_002996263.1 518740 D 486410 CDS YP_002996264.1 251781962 8110557 519740..521074 1 NC_012891.1 similar to 1,2-diacylglycerol 3-glucosyltransferase [Streptococcus pyogenes MGAS10270]; 1,2-diacylglycerol 3-glucosyltransferase 521074 8110557 SDEG_0548 Streptococcus dysgalactiae subsp. equisimilis GGS_124 1,2-diacylglycerol 3-glucosyltransferase YP_002996264.1 519740 D 486410 CDS YP_002996265.1 251781963 8110558 521498..523441 1 NC_012891.1 catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr); threonyl-tRNA synthetase 523441 thrS 8110558 thrS Streptococcus dysgalactiae subsp. equisimilis GGS_124 threonyl-tRNA synthetase YP_002996265.1 521498 D 486410 CDS YP_002996266.1 251781964 8110521 523571..524563 1 NC_012891.1 similar to ABC transporter ATP-binding protein [Streptococcus pyogenesstr. Manfredo]; ABC transporter ATP-binding protein 524563 8110521 SDEG_0550 Streptococcus dysgalactiae subsp. equisimilis GGS_124 ABC transporter ATP-binding protein YP_002996266.1 523571 D 486410 CDS YP_002996267.1 251781965 8110559 524565..525197 1 NC_012891.1 similar to daunorubicin resistance transmembrane protein [Streptococcus pyogenes MGAS5005]; daunorubicin resistance transmembrane protein 525197 8110559 SDEG_0551 Streptococcus dysgalactiae subsp. equisimilis GGS_124 daunorubicin resistance transmembrane protein YP_002996267.1 524565 D 486410 CDS YP_002996268.1 251781966 8110560 525185..525382 1 NC_012891.1 similar to daunorubicin resistance transmembrane protein [Streptococcus pyogenes MGAS10750]; daunorubicin resistance transmembrane protein 525382 8110560 SDEG_0552 Streptococcus dysgalactiae subsp. equisimilis GGS_124 daunorubicin resistance transmembrane protein YP_002996268.1 525185 D 486410 CDS YP_002996269.1 251781967 8110561 525384..526169 1 NC_012891.1 similar to ABC transporter permease protein [Streptococcus pyogenes MGAS10750]; ABC transporter permease 526169 8110561 SDEG_0553 Streptococcus dysgalactiae subsp. equisimilis GGS_124 ABC transporter permease YP_002996269.1 525384 D 486410 CDS YP_002996270.1 251781968 8110562 complement(526273..527262) 1 NC_012891.1 similar to DhaK; in Lactococcus lactis this protein froms a stable complex with DhaS and activates transcription of the dha operon in the presence of dihydroxyacetone; DhaKLM operon coactivator DhaQ 527262 8110562 SDEG_0554 Streptococcus dysgalactiae subsp. equisimilis GGS_124 DhaKLM operon coactivator DhaQ YP_002996270.1 526273 R 486410 CDS YP_002996271.1 251781969 8110563 complement(527277..527813) 1 NC_012891.1 similar to hypothetical protein SpyM51438 [Streptococcus pyogenes str.Manfredo]; hypothetical protein 527813 8110563 SDEG_0555 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996271.1 527277 R 486410 CDS YP_002996272.1 251781970 8110564 527965..528954 1 NC_012891.1 with DhaL and DhaM forms dihydroxyacetone kinase, which is responsible for phosphorylating dihydroxyacetone; DhaK is the dihydroxyacetone binding subunit of the dihydroxyacetone kinase; dihydroxyacetone kinase subunit DhaK 528954 8110564 SDEG_0556 Streptococcus dysgalactiae subsp. equisimilis GGS_124 dihydroxyacetone kinase subunit DhaK YP_002996272.1 527965 D 486410 CDS YP_002996273.1 251781971 8110565 528965..529540 1 NC_012891.1 similar to dihydroxyacetone kinase family protein [Streptococcus pyogenes str. Manfredo]; dihydroxyacetone kinase 529540 8110565 SDEG_0557 Streptococcus dysgalactiae subsp. equisimilis GGS_124 dihydroxyacetone kinase YP_002996273.1 528965 D 486410 CDS YP_002996274.1 251781972 8110566 529540..529914 1 NC_012891.1 similar to dihydroxyacetone kinase phosphotransfer protein [Streptococcus pyogenes MGAS10394]; PTS system transporter subunit IIA 529914 8110566 SDEG_0558 Streptococcus dysgalactiae subsp. equisimilis GGS_124 PTS system transporter subunit IIA YP_002996274.1 529540 D 486410 CDS YP_002996275.1 251781973 8110567 529932..530642 1 NC_012891.1 similar to glycerol uptake facilitator protein [Streptococcus pyogenes MGAS10394]; glycerol uptake facilitator protein 530642 8110567 SDEG_0559 Streptococcus dysgalactiae subsp. equisimilis GGS_124 glycerol uptake facilitator protein YP_002996275.1 529932 D 486410 CDS YP_002996276.1 251781974 8110568 530776..531345 1 NC_012891.1 similar to hypothetical protein SpyM51433 [Streptococcus pyogenes str.Manfredo]; hypothetical protein 531345 8110568 SDEG_0560 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996276.1 530776 D 486410 CDS YP_002996277.1 251781975 8110569 531308..532429 1 NC_012891.1 similar to acetyl-CoA acetyltransferase [Streptococcus pyogenes MGAS5005]; acetyl-CoA acetyltransferase 532429 8110569 SDEG_0561 Streptococcus dysgalactiae subsp. equisimilis GGS_124 acetyl-CoA acetyltransferase YP_002996277.1 531308 D 486410 CDS YP_002996278.1 251781976 8110570 532419..533663 1 NC_012891.1 similar to long-chain-fatty-acid-CoA ligase [Streptococcus pyogenes MGAS5005]; long-chain-fatty-acid-CoA ligase 533663 8110570 SDEG_0562 Streptococcus dysgalactiae subsp. equisimilis GGS_124 long-chain-fatty-acid-CoA ligase YP_002996278.1 532419 D 486410 CDS YP_002996279.1 251781977 8110571 533740..534753 1 NC_012891.1 similar to hypothetical cytosolic protein [Streptococcus pyogenes MGAS5005]; hypothetical protein 534753 8110571 SDEG_0563 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996279.1 533740 D 486410 CDS YP_002996280.1 251781978 8110572 complement(534849..535295) 1 NC_012891.1 similar to aminoacid (glutamine) ABC transporter permease protein [Streptococcus thermophilus CNRZ1066]; ABC transporter permease 535295 8110572 SDEG_0564 Streptococcus dysgalactiae subsp. equisimilis GGS_124 ABC transporter permease YP_002996280.1 534849 R 486410 CDS YP_002996281.1 251781979 8110573 complement(535274..535495) 1 NC_012891.1 similar to amino acid ABC transporter integral membrane protein [Streptococcus mutans UA159]; amino acid ABC transporter permease 535495 glnP 8110573 glnP Streptococcus dysgalactiae subsp. equisimilis GGS_124 amino acid ABC transporter permease YP_002996281.1 535274 R 486410 CDS YP_002996282.1 251781980 8112004 complement(535510..536211) 1 NC_012891.1 similar to hypothetical protein gbs0689 [Streptococcus agalactiae NEM316]; hypothetical protein 536211 8112004 SDEG_0566 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996282.1 535510 R 486410 CDS YP_002996283.1 251781981 8110574 complement(536225..537031) 1 NC_012891.1 similar to amino acid ABC transporter, amino acid-binding protein [Streptococcus agalactiae 2603V/R]; amino acid ABC transporter substrate-binding protein 537031 8110574 SDEG_0567 Streptococcus dysgalactiae subsp. equisimilis GGS_124 amino acid ABC transporter substrate-binding protein YP_002996283.1 536225 R 486410 CDS YP_002996284.1 251781982 8110575 complement(537025..537897) 1 NC_012891.1 similar to aminoacid (glutamine) ABC transporter ATP-binding protein [Streptococcus thermophilus CNRZ1066]; ABC transporter ATP-binding protein 537897 8110575 SDEG_0568 Streptococcus dysgalactiae subsp. equisimilis GGS_124 ABC transporter ATP-binding protein YP_002996284.1 537025 R 486410 CDS YP_002996285.1 251781983 8110576 538077..538787 1 NC_012891.1 similar to two-component response regulator [Streptococcus pyogenes MGAS5005]; two-component response regulator 538787 vicR 8110576 vicR Streptococcus dysgalactiae subsp. equisimilis GGS_124 two-component response regulator YP_002996285.1 538077 D 486410 CDS YP_002996286.1 251781984 8111949 538780..540132 1 NC_012891.1 similar to two-component sensor histidine kinase [Streptococcus pyogenes MGAS5005]; two-component sensor histidine kinase 540132 vicK 8111949 vicK Streptococcus dysgalactiae subsp. equisimilis GGS_124 two-component sensor histidine kinase YP_002996286.1 538780 D 486410 CDS YP_002996287.1 251781985 8111948 540136..540945 1 NC_012891.1 similar to Zn-dependent hydrolase [Streptococcus pyogenes MGAS5005]; Zn-dependent hydrolase 540945 vicX 8111948 vicX Streptococcus dysgalactiae subsp. equisimilis GGS_124 Zn-dependent hydrolase YP_002996287.1 540136 D 486410 CDS YP_002996288.1 251781986 8111950 541703..542395 1 NC_012891.1 cytoplasmic enzyme involved in processing rRNA and some mRNAs; substrates typically have dsRNA regions; forms a homodimer; have N-terminal nuclease and C-terminal RNA-binding domains; requires magnesium as preferred ion for activity; ribonuclease III 542395 rnc 8111950 rnc Streptococcus dysgalactiae subsp. equisimilis GGS_124 ribonuclease III YP_002996288.1 541703 D 486410 CDS YP_002996289.1 251781987 8110933 542396..545941 1 NC_012891.1 similar to chromosome partition protein [Streptococcus pyogenes MGAS5005]; chromosome partition protein 545941 smc 8110933 smc Streptococcus dysgalactiae subsp. equisimilis GGS_124 chromosome partition protein YP_002996289.1 542396 D 486410 CDS YP_002996290.1 251781988 8110490 546281..546928 1 NC_012891.1 similar to CspA [Streptococcus agalactiae]; cell-surface protease required for virulence cell 546928 cspA 8110490 cspA Streptococcus dysgalactiae subsp. equisimilis GGS_124 cell-surface protease required for virulence cell YP_002996290.1 546281 D 486410 CDS YP_002996291.1 251781989 8111652 547168..548010 1 NC_012891.1 similar to reticulocyte binding protein [Streptococcus agalactiae 515]; reticulocyte binding protein 548010 8111652 SDEG_0575 Streptococcus dysgalactiae subsp. equisimilis GGS_124 reticulocyte binding protein YP_002996291.1 547168 D 486410 CDS YP_002996292.1 251781990 8110577 548250..548636 1 NC_012891.1 similar to HAD superfamily hydrolase [Streptococcus pyogenes MGAS5005]; hydrolase 548636 8110577 SDEG_0576 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hydrolase YP_002996292.1 548250 D 486410 CDS YP_002996293.1 251781991 8110578 548680..549048 1 NC_012891.1 similar to HAD superfamily hydrolase [Streptococcus pyogenes MGAS5005]; hydrolase 549048 8110578 SDEG_0577 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hydrolase YP_002996293.1 548680 D 486410 CDS YP_002996294.1 251781992 8110579 549052..549876 1 NC_012891.1 similar to HAD superfamily hydrolase [Streptococcus pyogenes MGAS5005]; hydrolase 549876 8110579 SDEG_0578 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hydrolase YP_002996294.1 549052 D 486410 CDS YP_002996295.1 251781993 8110580 549876..551426 1 NC_012891.1 similar to cell division protein [Streptococcus pyogenes MGAS5005]; cell division protein 551426 ftzY 8110580 ftzY Streptococcus dysgalactiae subsp. equisimilis GGS_124 cell division protein YP_002996295.1 549876 D 486410 CDS YP_002996296.1 251781994 8111980 complement(551479..552597) 1 NC_012891.1 similar to multidrug resistance protein B [Streptococcus pyogenes MGAS5005]; multidrug resistance protein B 552597 8111980 SDEG_0580 Streptococcus dysgalactiae subsp. equisimilis GGS_124 multidrug resistance protein B YP_002996296.1 551479 R 486410 CDS YP_002996297.1 251781995 8110581 complement(552473..552844) 1 NC_012891.1 similar to major facilitator superfamily protein [Streptococcus pyogenes str. Manfredo]; major facilitator superfamily protein 552844 8110581 SDEG_0581 Streptococcus dysgalactiae subsp. equisimilis GGS_124 major facilitator superfamily protein YP_002996297.1 552473 R 486410 CDS YP_002996298.1 251781996 8110582 553172..554014 1 NC_012891.1 similar to transcription antiterminator; transcription antiterminator 554014 8110582 SDEG_0582 Streptococcus dysgalactiae subsp. equisimilis GGS_124 transcription antiterminator YP_002996298.1 553172 D 486410 CDS YP_002996299.1 251781997 8110583 554016..555878 1 NC_012891.1 similar to PTS system beta-glucoside-specific IIABC component [Streptococcus pyogenes MGAS5005]; PTS system protein 555878 8110583 SDEG_0583 Streptococcus dysgalactiae subsp. equisimilis GGS_124 PTS system protein YP_002996299.1 554016 D 486410 CDS YP_002996300.1 251781998 8110584 555897..557321 1 NC_012891.1 similar to 6-phospho-beta-glucosidase [Streptococcus pyogenes MGAS5005]; 6-phospho-beta-glucosidase 557321 bglA 8110584 bglA Streptococcus dysgalactiae subsp. equisimilis GGS_124 6-phospho-beta-glucosidase YP_002996300.1 555897 D 486410 CDS YP_002996301.1 251781999 8112372 complement(557420..558259) 1 NC_012891.1 similar to hypothetical membrane spanning protein [Streptococcus pyogenesMGAS5005]; hypothetical protein 558259 8112372 SDEG_0585 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996301.1 557420 R 486410 CDS YP_002996302.1 251782000 8110585 complement(558235..559137) 1 NC_012891.1 similar to hypothetical membrane spanning protein [Streptococcus pyogenesMGAS5005]; hypothetical protein 559137 8110585 SDEG_0586 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996302.1 558235 R 486410 CDS YP_002996303.1 251782001 8110586 complement(559284..559439) 1 NC_012891.1 similar to hypothetical protein MGAS9429 Spy0471 [Streptococcus pyogenes MGAS9429]; hypothetical protein 559439 8110586 SDEG_0587 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996303.1 559284 R 486410 CDS YP_002996304.1 251782002 8110587 559611..560096 1 NC_012891.1 similar to hypothetical protein spr1892 [Streptococcus pneumoniae R6]; hypothetical protein 560096 8110587 SDEG_0588 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996304.1 559611 D 486410 CDS YP_002996305.1 251782003 8110588 560183..560890 1 NC_012891.1 similar to response regulator [Streptococcus pneumoniae R6]; two-component response regulator 560890 phoP 8110588 phoP Streptococcus dysgalactiae subsp. equisimilis GGS_124 two-component response regulator YP_002996305.1 560183 D 486410 CDS YP_002996306.1 251782004 8111293 560891..562219 1 NC_012891.1 similar to histidine kinase [Streptococcus pneumoniae R6]; two-component sensor histidine kinase 562219 pnpS 8111293 pnpS Streptococcus dysgalactiae subsp. equisimilis GGS_124 two-component sensor histidine kinase YP_002996306.1 560891 D 486410 CDS YP_002996307.1 251782005 8111297 562377..563261 1 NC_012891.1 similar to phosphate ABC transporter, phosphate-binding protein [Streptococcus pneumoniae SP9-BS68]; phosphate ABC transporter substrate-binding protein 563261 8111297 SDEG_0591 Streptococcus dysgalactiae subsp. equisimilis GGS_124 phosphate ABC transporter substrate-binding protein YP_002996307.1 562377 D 486410 CDS YP_002996308.1 251782006 8110589 563379..564242 1 NC_012891.1 similar to phosphate ABC transporter permease protein [Streptococcus pneumoniae TIGR4]; phosphate ABC transporter 564242 8110589 SDEG_0592 Streptococcus dysgalactiae subsp. equisimilis GGS_124 phosphate ABC transporter YP_002996308.1 563379 D 486410 CDS YP_002996309.1 251782007 8110590 564235..565050 1 NC_012891.1 similar to phosphate ABC transporter permease protein [Streptococcus pneumoniae TIGR4]; phosphate ABC transporter 565050 8110590 SDEG_0593 Streptococcus dysgalactiae subsp. equisimilis GGS_124 phosphate ABC transporter YP_002996309.1 564235 D 486410 CDS YP_002996310.1 251782008 8110591 565052..565804 1 NC_012891.1 ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation; phosphate transporter ATP-binding protein 565804 8110591 SDEG_0594 Streptococcus dysgalactiae subsp. equisimilis GGS_124 phosphate transporter ATP-binding protein YP_002996310.1 565052 D 486410 CDS YP_002996311.1 251782009 8110592 565822..566472 1 NC_012891.1 similar to negative regulator of pho regulon for phosphate transport [Streptococcus pneumoniae R6]; negative regulator of pho regulon for phosphate transport 566472 8110592 SDEG_0595 Streptococcus dysgalactiae subsp. equisimilis GGS_124 negative regulator of pho regulon for phosphate transport YP_002996311.1 565822 D 486410 CDS YP_002996312.1 251782010 8110593 567272..569404 1 NC_012891.1 similar to hypothetical protein SPy 0580 [Streptococcus pyogenes M1 GAS]; hypothetical protein 569404 8110593 SDEG_0596 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996312.1 567272 D 486410 CDS YP_002996313.1 251782011 8110594 569346..569828 1 NC_012891.1 similar to hypothetical protein M5005 Spy 0482 [Streptococcus pyogenes MGAS5005]; hypothetical protein 569828 8110594 SDEG_0597 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996313.1 569346 D 486410 CDS YP_002996314.1 251782012 8110595 569892..570164 1 NC_012891.1 similar to hypothetical protein SpyM51378 [Streptococcus pyogenes str. Manfredo]; hypothetical protein 570164 8110595 SDEG_0598 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996314.1 569892 D 486410 CDS YP_002996315.1 251782013 8110596 570384..571376 1 NC_012891.1 catalyzes the phosphorylation of the phosphocarrier protein HPr of the bacterial phosphotransferase system; HPr kinase/phosphorylase 571376 ptsK 8110596 ptsK Streptococcus dysgalactiae subsp. equisimilis GGS_124 HPr kinase/phosphorylase YP_002996315.1 570384 D 486410 CDS YP_002996316.1 251782014 8111327 571373..572152 1 NC_012891.1 transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein; prolipoprotein diacylglyceryl transferase 572152 lgt 8111327 lgt Streptococcus dysgalactiae subsp. equisimilis GGS_124 prolipoprotein diacylglyceryl transferase YP_002996316.1 571373 D 486410 CDS YP_002996317.1 251782015 8110894 572174..572578 1 NC_012891.1 similar to hypothetical protein M5005 Spy 0486 [Streptococcus pyogenes MGAS5005]; hypothetical protein 572578 8110894 SDEG_0601 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996317.1 572174 D 486410 CDS YP_002996318.1 251782016 8110597 572575..573012 1 NC_012891.1 similar to hypothetical protein MGAS10750 Spy0508 [Streptococcus pyogenes MGAS10750]; hypothetical protein 573012 8110597 SDEG_0602 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996318.1 572575 D 486410 CDS YP_002996319.1 251782017 8110598 complement(573176..573460) 1 NC_012891.1 similar to hypothetical protein SpyM51373 [Streptococcus pyogenes str.Manfredo]; hypothetical protein 573460 8110598 SDEG_0603 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996319.1 573176 R 486410 CDS YP_002996320.1 251782018 8110599 573608..574585 1 NC_012891.1 similar to peptidase [Streptococcus pyogenes str. Manfredo]; peptidase 574585 8110599 SDEG_0604 Streptococcus dysgalactiae subsp. equisimilis GGS_124 peptidase YP_002996320.1 573608 D 486410 CDS YP_002996321.1 251782019 8110600 574687..575973 1 NC_012891.1 similar to peptidase family U32 [Streptococcus pyogenes MGAS5005]; peptidase family U32 575973 8110600 SDEG_0605 Streptococcus dysgalactiae subsp. equisimilis GGS_124 peptidase family U32 YP_002996321.1 574687 D 486410 CDS YP_002996322.1 251782020 8110601 576178..576390 1 NC_012891.1 similar to hypothetical cytosolic protein [Streptococcus pyogenes MGAS10750]; hypothetical protein 576390 8110601 SDEG_0606 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996322.1 576178 D 486410 CDS YP_002996323.1 251782021 8110602 complement(576492..576635) 1 NC_012891.1 similar to hypothetical protein M28 Spy0473 [Streptococcus pyogenes MGAS6180]; hypothetical protein 576635 8110602 SDEG_0607 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996323.1 576492 R 486410 CDS YP_002996324.1 251782022 8110603 complement(576684..577811) 1 NC_012891.1 similar to hypothetical protein SAG1433 [Streptococcus agalactiae 2603V/R]; hypothetical protein 577811 8110603 SDEG_0608 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996324.1 576684 R 486410 CDS YP_002996325.1 251782023 8110604 577915..578952 1 NC_012891.1 similar to ammonium transporter (Amt) family protein [Streptococcus agalactiae A909]; ammonium transporter (Amt) family protein 578952 8110604 SDEG_0609 Streptococcus dysgalactiae subsp. equisimilis GGS_124 ammonium transporter (Amt) family protein YP_002996325.1 577915 D 486410 CDS YP_002996326.1 251782024 8110605 complement(579029..580534) 1 NC_012891.1 class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1; lysyl-tRNA synthetase 580534 lysS 8110605 lysS Streptococcus dysgalactiae subsp. equisimilis GGS_124 lysyl-tRNA synthetase YP_002996326.1 579029 R 486410 CDS YP_002996327.1 251782025 8110913 580696..581598 1 NC_012891.1 similar to HAD superfamily hydrolase [Streptococcus pyogenes MGAS5005]; hydrolase 581598 8110913 SDEG_0611 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hydrolase YP_002996327.1 580696 D 486410 CDS YP_002996328.1 251782026 8110606 complement(581782..582402) 1 NC_012891.1 similar to phosphoglycerate mutase [Streptococcus pyogenes MGAS5005]; phosphoglycerate mutase 582402 8110606 SDEG_0612 Streptococcus dysgalactiae subsp. equisimilis GGS_124 phosphoglycerate mutase YP_002996328.1 581782 R 486410 CDS YP_002996329.1 251782027 8110607 complement(582415..582780) 1 NC_012891.1 similar to conserved hypothetical protein; integral membrane protein [Streptococcus mutans UA159]; hypothetical protein 582780 8110607 SDEG_0613 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996329.1 582415 R 486410 CDS YP_002996330.1 251782028 8110608 complement(582777..583262) 1 NC_012891.1 similar to transcription regulator [Streptococcus pyogenes MGAS8232]; transcriptional regulator 583262 8110608 SDEG_0614 Streptococcus dysgalactiae subsp. equisimilis GGS_124 transcriptional regulator YP_002996330.1 582777 R 486410 CDS YP_002996331.1 251782029 8110609 complement(583348..583944) 1 NC_012891.1 similar to hypothetical protein SpyM51364 [Streptococcus pyogenes str.Manfredo]; hypothetical protein 583944 8110609 SDEG_0615 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996331.1 583348 R 486410 CDS YP_002996332.1 251782030 8112217 complement(584193..585035) 1 NC_012891.1 similar to N-acetylmuramoyl-L-alanine amidase [Streptococcus pyogenes MGAS10750]; N-acetylmuramoyl-L-alanine amidase 585035 8112217 SDEG_0616 Streptococcus dysgalactiae subsp. equisimilis GGS_124 N-acetylmuramoyl-L-alanine amidase YP_002996332.1 584193 R 486410 CDS YP_002996333.1 251782031 8112218 585359..585862 1 NC_012891.1 similar to integral membrane protein [Streptococcus pyogenes MGAS10750]; integral membrane protein 585862 8112218 SDEG_0617 Streptococcus dysgalactiae subsp. equisimilis GGS_124 integral membrane protein YP_002996333.1 585359 D 486410 CDS YP_002996334.1 251782032 8112219 585846..586229 1 NC_012891.1 similar to hypothetical protein MGAS10270 Spy0496 [Streptococcus pyogenes MGAS10270]; hypothetical protein 586229 8112219 SDEG_0618 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996334.1 585846 D 486410 CDS YP_002996335.1 251782033 8112220 complement(586275..586799) 1 NC_012891.1 similar to glutathione peroxidase [Streptococcus pyogenes MGAS5005]; glutathione peroxidase 586799 8112220 SDEG_0619 Streptococcus dysgalactiae subsp. equisimilis GGS_124 glutathione peroxidase YP_002996335.1 586275 R 486410 CDS YP_002996336.1 251782034 8112221 complement(586747..588546) 1 NC_012891.1 similar to oligoendopeptidase F [Streptococcus pyogenes MGAS5005]; oligoendopeptidase F 588546 pepF 8112221 pepF Streptococcus dysgalactiae subsp. equisimilis GGS_124 oligoendopeptidase F YP_002996336.1 586747 R 486410 CDS YP_002996337.1 251782035 8111276 588677..591508 1 NC_012891.1 catalyzes the formation of oxaloacetate from phosphoenolpyruvate; phosphoenolpyruvate carboxylase 591508 ppc 8111276 ppc Streptococcus dysgalactiae subsp. equisimilis GGS_124 phosphoenolpyruvate carboxylase YP_002996337.1 588677 D 486410 CDS YP_002996338.1 251782036 8111302 591696..593000 1 NC_012891.1 similar to cell division protein [Streptococcus pyogenes MGAS5005]; cell division protein 593000 ftsW 8111302 ftsW Streptococcus dysgalactiae subsp. equisimilis GGS_124 cell division protein YP_002996338.1 591696 D 486410 CDS YP_002996339.1 251782037 8111976 593071..593580 1 NC_012891.1 similar to DNA-directed RNA polymerase specialized sigma subunit [Streptococcus suis 98HAH33]; DNA-directed RNA polymerase specialized sigma subunit 593580 8111976 SDEG_0623 Streptococcus dysgalactiae subsp. equisimilis GGS_124 DNA-directed RNA polymerase specialized sigma subunit YP_002996339.1 593071 D 486410 CDS YP_002996340.1 251782038 8112222 593564..594643 1 NC_012891.1 similar to hypothetical protein Sez 1324 [Streptococcus equi subsp. zooepidemicus MGCS10565]; hypothetical protein 594643 8112222 SDEG_0624 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996340.1 593564 D 486410 CDS YP_002996341.1 251782039 8112223 594751..595965 1 NC_012891.1 EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu; elongation factor Tu 595965 8112223 SDEG_0625 Streptococcus dysgalactiae subsp. equisimilis GGS_124 elongation factor Tu YP_002996341.1 594751 D 486410 CDS YP_002996342.1 251782040 8112224 596276..596707 1 NC_012891.1 similar to hypothetical protein SAG1552 [Streptococcus agalactiae 2603V/R]; hypothetical protein 596707 8112224 SDEG_0626 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996342.1 596276 D 486410 CDS YP_002996343.1 251782041 8112225 596871..597098 1 NC_012891.1 similar to hypothetical protein gbs1605 [Streptococcus agalactiae NEM316]; hypothetical protein 597098 8112225 SDEG_0627 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996343.1 596871 D 486410 CDS YP_002996344.1 251782042 8112226 597076..598299 1 NC_012891.1 similar to glycosyl transferase group 2 family protein [Streptococcus agalactiae 2603V/R]; glycosyl transferase group 2 598299 8112226 SDEG_0628 Streptococcus dysgalactiae subsp. equisimilis GGS_124 glycosyl transferase group 2 YP_002996344.1 597076 D 486410 CDS YP_002996345.1 251782043 8112227 598465..599223 1 NC_012891.1 Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate; triosephosphate isomerase 599223 tpiA 8112227 tpiA Streptococcus dysgalactiae subsp. equisimilis GGS_124 triosephosphate isomerase YP_002996345.1 598465 D 486410 CDS YP_002996346.1 251782044 8111921 complement(599291..600295) 1 NC_012891.1 similar to transposase [Streptococcus thermophilus LMD-9]; transposase 600295 8111921 SDEG_0630 Streptococcus dysgalactiae subsp. equisimilis GGS_124 transposase YP_002996346.1 599291 R 486410 CDS YP_002996347.1 251782045 8112228 complement(600321..600431) 1 NC_012891.1 similar to ORFA transposon ISSsa1 [Streptococcus sanguinis SK36]; ISSsa1 transposon OrfA 600431 8112228 SDEG_0631 Streptococcus dysgalactiae subsp. equisimilis GGS_124 ISSsa1 transposon OrfA YP_002996347.1 600321 R 486410 CDS YP_002996348.1 251782046 8112229 complement(600458..600658) 1 NC_012891.1 similar to transposase [Streptococcus pyogenes MGAS10394]; transposase 600658 8112229 SDEG_0632 Streptococcus dysgalactiae subsp. equisimilis GGS_124 transposase YP_002996348.1 600458 R 486410 CDS YP_002996349.1 251782047 8112230 complement(600873..601583) 1 NC_012891.1 similar to ISSdy1 transposase OrfB [Streptococcus agalactiae 2603V/R]; ISSdy1, transposase OrfB 601583 8112230 SDEG_0633 Streptococcus dysgalactiae subsp. equisimilis GGS_124 ISSdy1, transposase OrfB YP_002996349.1 600873 R 486410 CDS YP_002996350.1 251782048 8112231 complement(601619..601909) 1 NC_012891.1 similar to hypothetical protein gbs1310 [Streptococcus agalactiae NEM316]; hypothetical protein 601909 8112231 SDEG_0634 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996350.1 601619 R 486410 CDS YP_002996351.1 251782049 8112232 complement(601962..602135) 1 NC_012891.1 similar to L-lactate dehydrogenase (FMN-dependent) related alpha-hydroxy acid dehydrogenase [Pediococcus pentosaceus ATCC 25745]; L-lactate dehydrogenase (FMN-dependent) related alpha-hydroxy acid dehydrogenase 602135 8112232 SDEG_0635 Streptococcus dysgalactiae subsp. equisimilis GGS_124 L-lactate dehydrogenase (FMN-dependent) related alpha-hydroxy acid dehydrogenase YP_002996351.1 601962 R 486410 CDS YP_002996352.1 251782050 8112233 complement(602259..603494) 1 NC_012891.1 similar to factor essential for expression of methicillin resistance [Streptococcus pyogenes MGAS5005]; factor essential for expression of methicillin resistance 603494 8112233 SDEG_0636 Streptococcus dysgalactiae subsp. equisimilis GGS_124 factor essential for expression of methicillin resistance YP_002996352.1 602259 R 486410 CDS YP_002996353.1 251782051 8112234 complement(603494..604726) 1 NC_012891.1 similar to UDP-N-acetylmuramoylpentapeptide-lysine N(6)-alanyltransferase/UDP-N-acetylmuramoyl pentapeptide-lysine N(6)-seryltransferase [Streptococcus pyogenes MGAS5005]; UDP-N-acetylmuramoylpentapeptide-lysine N(6)-alanyltransferase/UDP-N-acetylmuramoylpentapeptide- lysine N(6)-seryltransferase 604726 murM 8112234 murM Streptococcus dysgalactiae subsp. equisimilis GGS_124 UDP-N-acetylmuramoylpentapeptide-lysine N(6)-alanyltransferase/UDP-N-acetylmuramoylpentapeptide- lysine N(6)-seryltransferase YP_002996353.1 603494 R 486410 CDS YP_002996354.1 251782052 8111689 complement(604711..605520) 1 NC_012891.1 similar to HAD superfamily hydrolase [Streptococcus pyogenes MGAS9429]; HAD superfamily hydrolase 605520 8111689 SDEG_0638 Streptococcus dysgalactiae subsp. equisimilis GGS_124 HAD superfamily hydrolase YP_002996354.1 604711 R 486410 CDS YP_002996355.1 251782053 8112235 complement(606001..607302) 1 NC_012891.1 similar to dGTP triphosphohydrolase [Streptococcus pyogenes MGAS5005]; dGTP triphosphohydrolase 607302 8112235 SDEG_0639 Streptococcus dysgalactiae subsp. equisimilis GGS_124 dGTP triphosphohydrolase YP_002996355.1 606001 R 486410 CDS YP_002996356.1 251782054 8112236 607384..607791 1 NC_012891.1 similar to hypothetical cytosolic protein [Streptococcus pyogenes MGAS5005]; hypothetical protein 607791 8112236 SDEG_0640 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996356.1 607384 D 486410 CDS YP_002996357.1 251782055 8112237 608119..610800 1 NC_012891.1 similar to calcium-transporting ATPase [Streptococcus pyogenes M1GAS]; calcium-transporting ATPase 610800 pacL 8112237 pacL Streptococcus dysgalactiae subsp. equisimilis GGS_124 calcium-transporting ATPase YP_002996357.1 608119 D 486410 CDS YP_002996358.1 251782056 8111749 complement(611410..612414) 1 NC_012891.1 similar to LacI family transcription regulator [Streptococcus pyogenes MGAS10394]; LacI family transcriptional regulator 612414 regR 8111749 regR Streptococcus dysgalactiae subsp. equisimilis GGS_124 LacI family transcriptional regulator YP_002996358.1 611410 R 486410 CDS YP_002996359.1 251782057 8111041 complement(612469..614394) 1 NC_012891.1 similar to oligohyaluronate lyase [Streptococcus pyogenes MGAS5005]; oligohyaluronate lyase 614394 8111041 SDEG_0643 Streptococcus dysgalactiae subsp. equisimilis GGS_124 oligohyaluronate lyase YP_002996359.1 612469 R 486410 CDS YP_002996360.1 251782058 8112238 complement(614463..615344) 1 NC_012891.1 similar to N-acetylgalactosamine-specific phosphotransferase system (PTS); PTS system N-acetylgalactosamine-specific transporter subunit IID 615344 agaD 8112238 agaD Streptococcus dysgalactiae subsp. equisimilis GGS_124 PTS system N-acetylgalactosamine-specific transporter subunit IID YP_002996360.1 614463 R 486410 CDS YP_002996361.1 251782059 8112314 complement(615271..616053) 1 NC_012891.1 similar to PTS system N-acetylgalactosamine-specific IIC component [Streptococcus pyogenes MGAS5005]; PTS system N-acetylgalactosamine-specific transporter subunit IIC 616053 8112314 SDEG_0645 Streptococcus dysgalactiae subsp. equisimilis GGS_124 PTS system N-acetylgalactosamine-specific transporter subunit IIC YP_002996361.1 615271 R 486410 CDS YP_002996362.1 251782060 8112239 complement(616072..616560) 1 NC_012891.1 similar to PTS system N-acetylgalactosamine-specific IIB component [Streptococcus pyogenes str. Manfredo]; PTS system protein 616560 agaV 8112239 agaV Streptococcus dysgalactiae subsp. equisimilis GGS_124 PTS system protein YP_002996362.1 616072 R 486410 CDS YP_002996363.1 251782061 8112316 complement(616596..617795) 1 NC_012891.1 similar to glucuronyl hydrolase [Streptococcus pyogenes MGAS5005]; glucuronyl hydrolase 617795 8112316 SDEG_0647 Streptococcus dysgalactiae subsp. equisimilis GGS_124 glucuronyl hydrolase YP_002996363.1 616596 R 486410 CDS YP_002996364.1 251782062 8112240 complement(617795..618232) 1 NC_012891.1 similar to N-acetylgalactosamine-specific phosphotransferase system (PTS); PTS system N-acetylgalactosamine-specific transporter subunit IIA 618232 8112240 SDEG_0648 Streptococcus dysgalactiae subsp. equisimilis GGS_124 PTS system N-acetylgalactosamine-specific transporter subunit IIA YP_002996364.1 617795 R 486410 CDS YP_002996365.1 251782063 8112241 617862..618266 1 NC_012891.1 similar to hypothetical protein M5005 Spy 0523 [Streptococcus pyogenes MGAS5005]; hypothetical protein 618266 8112241 SDEG_0649 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996365.1 617862 D 486410 CDS YP_002996366.1 251782064 8112242 618567..619361 1 NC_012891.1 Involved in the nonphosphorylative, ketogenic oxidation of glucose and oxidizes gluconate to 5-ketogluconate; gluconate 5-dehydrogenase 619361 idnO 8112242 idnO Streptococcus dysgalactiae subsp. equisimilis GGS_124 gluconate 5-dehydrogenase YP_002996366.1 618567 D 486410 CDS YP_002996367.1 251782065 8112047 619386..620027 1 NC_012891.1 similar to hypothetical protein M5005 Spy 0525 [Streptococcus pyogenes MGAS5005]; hypothetical protein 620027 8112047 SDEG_0651 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996367.1 619386 D 486410 CDS YP_002996368.1 251782066 8112243 620017..621057 1 NC_012891.1 similar to 2-dehydro-3-deoxygluconokinase [Streptococcus pyogenes MGAS5005]; 2-dehydro-3-deoxygluconokinase 621057 8112243 SDEG_0652 Streptococcus dysgalactiae subsp. equisimilis GGS_124 2-dehydro-3-deoxygluconokinase YP_002996368.1 620017 D 486410 CDS YP_002996369.1 251782067 8112244 621062..621700 1 NC_012891.1 catalyzes the formation of pyruvate and glyoxylate from 4-hydroxy-2-oxoglutarate; or pyruvate and D-glyceraldehyde 3-phosphate from 2-dehydro-3-deoxy-D-glyconate 6-phosphate; keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase 621700 kgdA 8112244 kgdA Streptococcus dysgalactiae subsp. equisimilis GGS_124 keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase YP_002996369.1 621062 D 486410 CDS YP_002996370.1 251782068 8110876 621725..624928 1 NC_012891.1 similar to hyaluronatelyase precursor HylB [Streptococcus equi subsp. zooepidemicus MGCS10565]; hyaluronate lyase 624928 hylB 8110876 hylB Streptococcus dysgalactiae subsp. equisimilis GGS_124 hyaluronate lyase YP_002996370.1 621725 D 486410 CDS YP_002996371.1 251782069 8112046 complement(625316..625810) 1 NC_012891.1 similar to hypothetical protein SSA 0868 [Streptococcus sanguinis SK36]; hypothetical protein 625810 8112046 SDEG_0655 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996371.1 625316 R 486410 CDS YP_002996372.1 251782070 8112245 complement(625901..626209) 1 NC_012891.1 similar to hypothetical protein SAG0515 [Streptococcus agalactiae 2603V/R]; hypothetical protein 626209 8112245 SDEG_0656 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996372.1 625901 R 486410 CDS YP_002996373.1 251782071 8112246 complement(626379..626972) 1 NC_012891.1 similar to transposase [Streptococcus pyogenes str. Manfredo]; transposase 626972 8112246 SDEG_0657 Streptococcus dysgalactiae subsp. equisimilis GGS_124 transposase YP_002996373.1 626379 R 486410 CDS YP_002996374.1 251782072 8112247 complement(627230..627505) 1 NC_012891.1 similar to probable transposase TnpA (fragment) [Streptococcus pyogenes MGAS315]; transposase TnpA 627505 8112247 SDEG_0658 Streptococcus dysgalactiae subsp. equisimilis GGS_124 transposase TnpA YP_002996374.1 627230 R 486410 CDS YP_002996375.1 251782073 8112248 627784..628428 1 NC_012891.1 similar to beta-phosphoglucomutase [Streptococcus pyogenes MGAS10394]; beta-phosphoglucomutase 628428 8112248 SDEG_0659 Streptococcus dysgalactiae subsp. equisimilis GGS_124 beta-phosphoglucomutase YP_002996375.1 627784 D 486410 CDS YP_002996376.1 251782074 8112249 628659..630572 1 NC_012891.1 similar to fructose-16-bisphosphatase [Streptococcus agalactiae 515]; fructose-1,6-bisphosphatase 630572 8112249 SDEG_0660 Streptococcus dysgalactiae subsp. equisimilis GGS_124 fructose-1,6-bisphosphatase YP_002996376.1 628659 D 486410 CDS YP_002996377.1 251782075 8112250 630780..631952 1 NC_012891.1 similar to iron-sulfur cluster-binding protein [Streptococcus pyogenes MGAS10394]; iron-sulfur cluster-binding protein 631952 8112250 SDEG_0661 Streptococcus dysgalactiae subsp. equisimilis GGS_124 iron-sulfur cluster-binding protein YP_002996377.1 630780 D 486410 CDS YP_002996378.1 251782076 8112251 632159..633154 1 NC_012891.1 recognizes the termination signals UGA and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF2; in some organisms control of PrfB protein levels is maintained through a +1 ribosomal frameshifting mechanism; this protein is similar to release factor 1; peptide chain release factor 2 633154 prfB 8112251 prfB Streptococcus dysgalactiae subsp. equisimilis GGS_124 peptide chain release factor 2 YP_002996378.1 632159 D 486410 CDS YP_002996379.1 251782077 8111306 633198..633890 1 NC_012891.1 similar to cell division ATP-binding protein [Streptococcus pyogenes MGAS5005]; cell division ATP-binding protein 633890 ftsE 8111306 ftsE Streptococcus dysgalactiae subsp. equisimilis GGS_124 cell division ATP-binding protein YP_002996379.1 633198 D 486410 CDS YP_002996380.1 251782078 8111915 633883..634812 1 NC_012891.1 similar to cell-division protein [Streptococcus pyogenes MGAS8232]; cell-division protein 634812 ftsX 8111915 ftsX Streptococcus dysgalactiae subsp. equisimilis GGS_124 cell-division protein YP_002996380.1 633883 D 486410 CDS YP_002996381.1 251782079 8111978 complement(634935..635582) 1 NC_012891.1 similar to Zn-dependenthydrolase including glyoxylases [Streptococcus suis05ZYH33]; hydroxyacylglutathione hydrolase 635582 8111978 SDEG_0665 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hydroxyacylglutathione hydrolase YP_002996381.1 634935 R 486410 CDS YP_002996382.1 251782080 8112252 635811..638273 1 NC_012891.1 unwinds DNA; bifunctional ATP-dependent DNA helicase/DNA polymerase III subunit epsilon 638273 dinG 8112252 dinG Streptococcus dysgalactiae subsp. equisimilis GGS_124 bifunctional ATP-dependent DNA helicase/DNA polymerase III subunit epsilon YP_002996382.1 635811 D 486410 CDS YP_002996383.1 251782081 8111673 638555..639751 1 NC_012891.1 catalyzes the formation of oxalozcetate and L-glutamate from L-aspartate and 2-oxoglutarate; aspartate aminotransferase 639751 aspC 8111673 aspC Streptococcus dysgalactiae subsp. equisimilis GGS_124 aspartate aminotransferase YP_002996383.1 638555 D 486410 CDS YP_002996384.1 251782082 8112351 639789..641135 1 NC_012891.1 catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; asparaginyl-tRNA synthetase 641135 asnC 8112351 asnC Streptococcus dysgalactiae subsp. equisimilis GGS_124 asparaginyl-tRNA synthetase YP_002996384.1 639789 D 486410 CDS YP_002996385.1 251782083 8112350 641426..642169 1 NC_012891.1 similar to hypothetical protein SMU.1307c [Streptococcus mutans UA159]; hypothetical protein 642169 8112350 SDEG_0669 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996385.1 641426 D 486410 CDS YP_002996386.1 251782084 8112253 642302..643192 1 NC_012891.1 similar to P-loop ATPase protein family protein [Streptococcus pyogenes str. Manfredo]; hypothetical protein 643192 8112253 SDEG_0670 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996386.1 642302 D 486410 CDS YP_002996387.1 251782085 8112254 643189..644166 1 NC_012891.1 similar to transporter [Streptococcus pyogenes MGAS5005]; transporter 644166 8112254 SDEG_0671 Streptococcus dysgalactiae subsp. equisimilis GGS_124 transporter YP_002996387.1 643189 D 486410 CDS YP_002996388.1 251782086 8112255 644163..645074 1 NC_012891.1 similar to hypothetical cytosolic protein [Streptococcus pyogenes MGAS5005]; hypothetical protein 645074 8112255 SDEG_0672 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996388.1 644163 D 486410 CDS YP_002996389.1 251782087 8112256 645207..646604 1 NC_012891.1 similar to dipeptidase [Streptococcus pyogenes MGAS5005]; dipeptidase 646604 pepD 8112256 pepD Streptococcus dysgalactiae subsp. equisimilis GGS_124 dipeptidase YP_002996389.1 645207 D 486410 CDS YP_002996390.1 251782088 8111275 646755..648302 1 NC_012891.1 similar to high-affinity zinc uptake system protein znuA precursor [Streptococcus pyogenes MGAS5005]; high-affinity zinc uptake system protein znuA 648302 znuA 8111275 znuA Streptococcus dysgalactiae subsp. equisimilis GGS_124 high-affinity zinc uptake system protein znuA YP_002996390.1 646755 D 486410 CDS YP_002996391.1 251782089 8111972 648451..649182 1 NC_012891.1 similar to transcriptional regulatorGntR family [Streptococcus pyogenes MGAS10750]; GntR family transcriptional regulator 649182 8111972 SDEG_0675 Streptococcus dysgalactiae subsp. equisimilis GGS_124 GntR family transcriptional regulator YP_002996391.1 648451 D 486410 CDS YP_002996392.1 251782090 8112257 649202..650380 1 NC_012891.1 similar to galactosamine-6-phosphate deaminase (isomerizing) [Streptococcus pyogenes MGAS5005]; galactosamine-6-phosphate deaminase 650380 agaS 8112257 agaS Streptococcus dysgalactiae subsp. equisimilis GGS_124 galactosamine-6-phosphate deaminase YP_002996392.1 649202 D 486410 CDS YP_002996393.1 251782091 8112315 650390..651199 1 NC_012891.1 similar to tagatose1,6-diphosphate aldolase [Streptococcus pyogenes MGAS5005]; tagatose1,6-diphosphate aldolase 651199 lacD.1 8112315 lacD.1 Streptococcus dysgalactiae subsp. equisimilis GGS_124 tagatose1,6-diphosphate aldolase YP_002996393.1 650390 D 486410 CDS YP_002996394.1 251782092 8110885 complement(651449..652162) 1 NC_012891.1 similar to transcriptional regulator [Streptococcus suis05ZYH33]; GntR family transcriptional regulator 652162 8110885 SDEG_0678 Streptococcus dysgalactiae subsp. equisimilis GGS_124 GntR family transcriptional regulator YP_002996394.1 651449 R 486410 CDS YP_002996395.1 251782093 8112258 652283..654067 1 NC_012891.1 similar to beta-galactosidase [Streptococcus suis89/1591]; beta-galactosidase 654067 bga 8112258 bga Streptococcus dysgalactiae subsp. equisimilis GGS_124 beta-galactosidase YP_002996395.1 652283 D 486410 CDS YP_002996396.1 251782094 8112370 654064..654549 1 NC_012891.1 similar to PTS systemmannose/fructose IIB component [Streptococcus equi subsp. zooepidemicus MGCS10565]; PTS system mannose/fructose transporter subunit IIB 654549 8112370 SDEG_0680 Streptococcus dysgalactiae subsp. equisimilis GGS_124 PTS system mannose/fructose transporter subunit IIB YP_002996396.1 654064 D 486410 CDS YP_002996397.1 251782095 8112259 654592..655494 1 NC_012891.1 similar to PTS system IIC component [Streptococcus pneumoniae TIGR4]; PTS system mannose/fructose transporter subunit IIC 655494 8112259 SDEG_0681 Streptococcus dysgalactiae subsp. equisimilis GGS_124 PTS system mannose/fructose transporter subunit IIC YP_002996397.1 654592 D 486410 CDS YP_002996398.1 251782096 8112260 655481..656296 1 NC_012891.1 similar to phosphotransferase system, mannose/fructose /N-acetylgalactosamine-specific component IID [Streptococcus suis 05ZYH33]; phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IID 656296 8112260 SDEG_0682 Streptococcus dysgalactiae subsp. equisimilis GGS_124 phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IID YP_002996398.1 655481 D 486410 CDS YP_002996399.1 251782097 8112261 656296..656700 1 NC_012891.1 similar to PTS system fructosesubfamily IIA component [Streptococcus suis 89/1591]; PTS system mannose/fructose transporter subunit IIAB 656700 8112261 SDEG_0683 Streptococcus dysgalactiae subsp. equisimilis GGS_124 PTS system mannose/fructose transporter subunit IIAB YP_002996399.1 656296 D 486410 CDS YP_002996400.1 251782098 8112262 complement(656911..657171) 1 NC_012891.1 RpmE2; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster do not have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome; 50S ribosomal protein L31 657171 rpmE2 8112262 rpmE2 Streptococcus dysgalactiae subsp. equisimilis GGS_124 50S ribosomal protein L31 YP_002996400.1 656911 R 486410 CDS YP_002996401.1 251782099 8111082 657437..657694 1 NC_012891.1 similar to transposase [Streptococcus pyogenes MGAS8232]; transposase 657694 8111082 SDEG_0685 Streptococcus dysgalactiae subsp. equisimilis GGS_124 transposase YP_002996401.1 657437 D 486410 CDS YP_002996402.1 251782100 8112263 657702..658391 1 NC_012891.1 similar to transposase [Streptococcus pyogenes MGAS10394]; transposase 658391 8112263 SDEG_0686 Streptococcus dysgalactiae subsp. equisimilis GGS_124 transposase YP_002996402.1 657702 D 486410 CDS YP_002996403.1 251782101 8112264 658461..658640 1 NC_012891.1 similar to transposase [Streptococcus pyogenes SSI-1]; transposase 658640 8112264 SDEG_0687 Streptococcus dysgalactiae subsp. equisimilis GGS_124 transposase YP_002996403.1 658461 D 486410 CDS YP_002996404.1 251782102 8112265 658743..659447 1 NC_012891.1 similar to transposase [Streptococcus pyogenes MGAS10270]; transposase 659447 8112265 SDEG_0688 Streptococcus dysgalactiae subsp. equisimilis GGS_124 transposase YP_002996404.1 658743 D 486410 CDS YP_002996405.1 251782103 8112266 complement(659550..660491) 1 NC_012891.1 similar to phosphoesterase DHH family protein [Streptococcus pyogenes MGAS10394]; phosphoesterase, DHH family protein 660491 8112266 SDEG_0689 Streptococcus dysgalactiae subsp. equisimilis GGS_124 phosphoesterase, DHH family protein YP_002996405.1 659550 R 486410 CDS YP_002996406.1 251782104 8112267 complement(660497..660928) 1 NC_012891.1 similar to GCN5-related N-acetyltransferase [Actinobacillus succinogenes 130Z]; acetyltransferase 660928 8112267 SDEG_0690 Streptococcus dysgalactiae subsp. equisimilis GGS_124 acetyltransferase YP_002996406.1 660497 R 486410 CDS YP_002996407.1 251782105 8112268 complement(661013..661792) 1 NC_012891.1 similar to glutathione S-transferase family [Streptococcus thermophilus LMG 18311]; glutathione S-transferase 661792 8112268 SDEG_0691 Streptococcus dysgalactiae subsp. equisimilis GGS_124 glutathione S-transferase YP_002996407.1 661013 R 486410 CDS YP_002996408.1 251782106 8112269 662043..663062 1 NC_012891.1 similar to adenosine deaminase [Streptococcus thermophilus LMG 18311]; adenosine deaminase 663062 add 8112269 add Streptococcus dysgalactiae subsp. equisimilis GGS_124 adenosine deaminase YP_002996408.1 662043 D 486410 CDS YP_002996409.1 251782107 8112310 663130..663579 1 NC_012891.1 An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group; flavodoxin 663579 8112310 SDEG_0693 Streptococcus dysgalactiae subsp. equisimilis GGS_124 flavodoxin YP_002996409.1 663130 D 486410 CDS YP_002996410.1 251782108 8112270 663755..664039 1 NC_012891.1 similar to hypothetical protein spyM18 0789 [StreptococcuspyogenesMGAS8232]; hypothetical protein 664039 cm 8112270 cm Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996410.1 663755 D 486410 CDS YP_002996411.1 251782109 8111626 664032..665294 1 NC_012891.1 similar to chloride channel protein [Streptococcus pyogenesMGAS5005]; chloride channel protein 665294 8111626 SDEG_0695 Streptococcus dysgalactiae subsp. equisimilis GGS_124 chloride channel protein YP_002996411.1 664032 D 486410 CDS YP_002996412.1 251782110 8112271 665409..665756 1 NC_012891.1 this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site; 50S ribosomal protein L19 665756 rplS 8112271 rplS Streptococcus dysgalactiae subsp. equisimilis GGS_124 50S ribosomal protein L19 YP_002996412.1 665409 D 486410 CDS YP_002996413.1 251782111 8112272 666378..667589 1 NC_012891.1 similar to cell division protein FtsW [Streptococcus equi subsp. zooepidemicus MGCS10565]; cell division protein FtsW 667589 ftsW 8112272 ftsW Streptococcus dysgalactiae subsp. equisimilis GGS_124 cell division protein FtsW YP_002996413.1 666378 D 486410 CDS YP_002996414.1 251782112 8111977 667682..668251 1 NC_012891.1 similar to DNA gyrase related protein [Streptococcus pyogenes MGAS10394]; DNA gyrase subunit B 668251 8111977 SDEG_0699 Streptococcus dysgalactiae subsp. equisimilis GGS_124 DNA gyrase subunit B YP_002996414.1 667682 D 486410 CDS YP_002996415.1 251782113 8112273 668252..670204 1 NC_012891.1 negatively supercoils closed circular double-stranded DNA; DNA gyrase subunit B 670204 gyrB 8112273 gyrB Streptococcus dysgalactiae subsp. equisimilis GGS_124 DNA gyrase subunit B YP_002996415.1 668252 D 486410 CDS YP_002996416.1 251782114 8112026 670554..672278 1 NC_012891.1 acts to negatively regulates ftsZ ring formation by modulating the frequency and position of the ftsZ ring formation; septation ring formation regulator EzrA 672278 8112026 SDEG_0701 Streptococcus dysgalactiae subsp. equisimilis GGS_124 septation ring formation regulator EzrA YP_002996416.1 670554 D 486410 CDS YP_002996417.1 251782115 8112274 672411..673079 1 NC_012891.1 similar to phosphoserine phosphatase [Streptococcus thermophilus LMG 18311]; phosphoserine phosphatase 673079 serB 8112274 serB Streptococcus dysgalactiae subsp. equisimilis GGS_124 phosphoserine phosphatase YP_002996417.1 672411 D 486410 CDS YP_002996418.1 251782116 8110481 complement(673106..673561) 1 NC_012891.1 similar to hypothetical cytosolic protein [Streptococcus pyogenes MGAS10394]; hypothetical protein 673561 8110481 SDEG_0703 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996418.1 673106 R 486410 CDS YP_002996419.1 251782117 8112275 673786..675093 1 NC_012891.1 enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis; phosphopyruvate hydratase 675093 eno 8112275 eno Streptococcus dysgalactiae subsp. equisimilis GGS_124 phosphopyruvate hydratase YP_002996419.1 673786 D 486410 CDS YP_002996420.1 251782118 8111871 675793..675954 1 NC_012891.1 similar to bacteriocin-like prepropeptide[Streptococcus dysgalactia subsp. equisimilis]; streptolysin S; bacteriocin-like prepropeptide 675954 sagA 8111871 sagA Streptococcus dysgalactiae subsp. equisimilis GGS_124 bacteriocin-like prepropeptide YP_002996420.1 675793 D 486410 CDS YP_002996421.1 251782119 8110453 676173..677123 1 NC_012891.1 similar to SagB [Streptococcus dysgalactiae subsp. equisimilis]; streptolysin S biosynthesis protein 677123 sagB 8110453 sagB Streptococcus dysgalactiae subsp. equisimilis GGS_124 streptolysin S biosynthesis protein YP_002996421.1 676173 D 486410 CDS YP_002996422.1 251782120 8110454 677120..678184 1 NC_012891.1 similar to streptolysin S biosynthesis protein [Streptococcus pyogenes MGAS5005]; streptolysin S biosynthesis protein 678184 sagC 8110454 sagC Streptococcus dysgalactiae subsp. equisimilis GGS_124 streptolysin S biosynthesis protein YP_002996422.1 677120 D 486410 CDS YP_002996423.1 251782121 8110455 678197..679555 1 NC_012891.1 similar to streptolysin Sbiosynthesis protein SagD [Streptococcus pyogenesMGAS10270]; streptolysin S biosynthesis protein 679555 sagD 8110455 sagD Streptococcus dysgalactiae subsp. equisimilis GGS_124 streptolysin S biosynthesis protein YP_002996423.1 678197 D 486410 CDS YP_002996424.1 251782122 8110456 679530..680204 1 NC_012891.1 similar to streptolysin S self-immunity protein [Streptococcus pyogenes MGAS5005]; streptolysin S self-immunity protein 680204 sagE 8110456 sagE Streptococcus dysgalactiae subsp. equisimilis GGS_124 streptolysin S self-immunity protein YP_002996424.1 679530 D 486410 CDS YP_002996425.1 251782123 8110457 680201..680887 1 NC_012891.1 similar to streptolysin S biosynthesis protein SagF [Streptococcus pyogenes MGAS10270]; streptolysin S biosynthesis protein 680887 sagF 8110457 sagF Streptococcus dysgalactiae subsp. equisimilis GGS_124 streptolysin S biosynthesis protein YP_002996425.1 680201 D 486410 CDS YP_002996426.1 251782124 8110458 680908..681831 1 NC_012891.1 similar to streptolysin S export ATP-binding protein [Streptococcus pyogenes MGAS5005]; streptolysin S export ATP-binding protein 681831 sagG 8110458 sagG Streptococcus dysgalactiae subsp. equisimilis GGS_124 streptolysin S export ATP-binding protein YP_002996426.1 680908 D 486410 CDS YP_002996427.1 251782125 8110459 681840..682967 1 NC_012891.1 similar to streptolysin S export transmembrane protein [Streptococcus pyogenes MGAS6180]; streptolysin S export transmembrane protein 682967 sagH 8110459 sagH Streptococcus dysgalactiae subsp. equisimilis GGS_124 streptolysin S export transmembrane protein YP_002996427.1 681840 D 486410 CDS YP_002996428.1 251782126 8110460 682964..684082 1 NC_012891.1 similar to streptolysin S export transmembrane protein [Streptococcus pyogenes MGAS5005]; streptolysin S export transmembrane protein 684082 sagI 8110460 sagI Streptococcus dysgalactiae subsp. equisimilis GGS_124 streptolysin S export transmembrane protein YP_002996428.1 682964 D 486410 CDS YP_002996429.1 251782127 8110461 684437..687262 1 NC_012891.1 similar to endonuclease/exonuclease /phosphatase family protein[Streptococcus pyogenes MGAS9429]; extracellular nuclease 687262 8110461 SDEG_0714 Streptococcus dysgalactiae subsp. equisimilis GGS_124 extracellular nuclease YP_002996429.1 684437 D 486410 CDS YP_002996430.1 251782128 8112276 687593..688096 1 NC_012891.1 similar to hypothetical membrane spanning protein [Streptococcus pyogenes MGAS6180]; hypothetical protein 688096 8112276 SDEG_0715 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996430.1 687593 D 486410 CDS YP_002996431.1 251782129 8112277 688243..690201 1 NC_012891.1 this protein catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction; essential for DNA replication and repair of damaged DNA; similar to ligase LigB; NAD-dependent DNA ligase LigA 690201 ligA 8112277 ligA Streptococcus dysgalactiae subsp. equisimilis GGS_124 NAD-dependent DNA ligase LigA YP_002996431.1 688243 D 486410 CDS YP_002996432.1 251782130 8110895 690214..691236 1 NC_012891.1 similar to YegS from E. coli; lipid kinase 691236 8110895 SDEG_0717 Streptococcus dysgalactiae subsp. equisimilis GGS_124 lipid kinase YP_002996432.1 690214 D 486410 CDS YP_002996433.1 251782131 8112278 691242..693545 1 NC_012891.1 pullulanase; similar to glycogen branching enzyme [Streptococcus mutans UA159]; glycogen debranching protein 693545 pulA 8112278 pulA Streptococcus dysgalactiae subsp. equisimilis GGS_124 glycogen debranching protein YP_002996433.1 691242 D 486410 CDS YP_002996434.1 251782132 8111328 693652..695532 1 NC_012891.1 catalyzes the transfer of a segment of a 1,4-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain; glycogen branching protein 695532 glgB 8111328 glgB Streptococcus dysgalactiae subsp. equisimilis GGS_124 glycogen branching protein YP_002996434.1 693652 D 486410 CDS YP_002996435.1 251782133 8111997 695671..696798 1 NC_012891.1 catalyzes the formation of ADP-glucose and diphosphate from ATP and alpha-D-glucose 1-phosphate; glucose-1-phosphate adenylyltransferase 696798 glgC 8111997 glgC Streptococcus dysgalactiae subsp. equisimilis GGS_124 glucose-1-phosphate adenylyltransferase YP_002996435.1 695671 D 486410 CDS YP_002996436.1 251782134 8111998 696788..697921 1 NC_012891.1 similar to glucose-1-phosphate adenylyltransferase GlgC [Streptococcus equi subsp. zooepidemicus MGCS10565]; glucose-1-phosphate adenylyltransferase 697921 glgC 8111998 glgC Streptococcus dysgalactiae subsp. equisimilis GGS_124 glucose-1-phosphate adenylyltransferase YP_002996436.1 696788 D 486410 CDS YP_002996437.1 251782135 8111999 697918..699357 1 NC_012891.1 catalyzes the formation of alpha-1,4-glucan chains from ADP-glucose; glycogen synthase 699357 glgA 8111999 glgA Streptococcus dysgalactiae subsp. equisimilis GGS_124 glycogen synthase YP_002996437.1 697918 D 486410 CDS YP_002996438.1 251782136 8111996 699622..699819 1 NC_012891.1 produces ATP from ADP in the presence of a proton gradient across the membrane; subunit C is part of the membrane proton channel F0; F0F1 ATP synthase subunit C 699819 atpE 8111996 atpE Streptococcus dysgalactiae subsp. equisimilis GGS_124 F0F1 ATP synthase subunit C YP_002996438.1 699622 D 486410 CDS YP_002996439.1 251782137 8112361 699854..700570 1 NC_012891.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0; F0F1 ATP synthase subunit A 700570 atpB 8112361 atpB Streptococcus dysgalactiae subsp. equisimilis GGS_124 F0F1 ATP synthase subunit A YP_002996439.1 699854 D 486410 CDS YP_002996440.1 251782138 8112358 700588..701082 1 NC_012891.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit B is part of the membrane proton channel.; F0F1 ATP synthase subunit B 701082 atpF 8112358 atpF Streptococcus dysgalactiae subsp. equisimilis GGS_124 F0F1 ATP synthase subunit B YP_002996440.1 700588 D 486410 CDS YP_002996441.1 251782139 8112362 701082..701618 1 NC_012891.1 Produces ATP from ADP in the presence of a proton gradient across the membrane; the delta subunit is part of the catalytic core of the ATP synthase complex; F0F1 ATP synthase subunit delta 701618 atpH 8112362 atpH Streptococcus dysgalactiae subsp. equisimilis GGS_124 F0F1 ATP synthase subunit delta YP_002996441.1 701082 D 486410 CDS YP_002996442.1 251782140 8112364 701634..703139 1 NC_012891.1 produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit; F0F1 ATP synthase subunit alpha 703139 atpA 8112364 atpA Streptococcus dysgalactiae subsp. equisimilis GGS_124 F0F1 ATP synthase subunit alpha YP_002996442.1 701634 D 486410 CDS YP_002996443.1 251782141 8112357 703158..704033 1 NC_012891.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is a regulatory subunit; F0F1 ATP synthase subunit gamma 704033 atpG 8112357 atpG Streptococcus dysgalactiae subsp. equisimilis GGS_124 F0F1 ATP synthase subunit gamma YP_002996443.1 703158 D 486410 CDS YP_002996444.1 251782142 8112363 704196..705602 1 NC_012891.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit; F0F1 ATP synthase subunit beta 705602 atpD 8112363 atpD Streptococcus dysgalactiae subsp. equisimilis GGS_124 F0F1 ATP synthase subunit beta YP_002996444.1 704196 D 486410 CDS YP_002996445.1 251782143 8112360 705615..706031 1 NC_012891.1 part of catalytic core of ATP synthase; alpha(3)beta(3)gamma(1)delta(1)epsilon(1); involved in producing ATP from ADP in the presence of the proton motive force across the membrane; F0F1 ATP synthase subunit epsilon 706031 atpC 8112360 atpC Streptococcus dysgalactiae subsp. equisimilis GGS_124 F0F1 ATP synthase subunit epsilon YP_002996445.1 705615 D 486410 CDS YP_002996446.1 251782144 8112359 706661..707932 1 NC_012891.1 adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active; UDP-N-acetylglucosamine 1-carboxyvinyltransferase 707932 murA 8112359 murA Streptococcus dysgalactiae subsp. equisimilis GGS_124 UDP-N-acetylglucosamine 1-carboxyvinyltransferase YP_002996446.1 706661 D 486410 CDS YP_002996447.1 251782145 8111682 708160..709026 1 NC_012891.1 similar to DNA-entry nuclease [Streptococcus pyogenes MGAS10394]; DNA-entry nuclease 709026 endA 8111682 endA Streptococcus dysgalactiae subsp. equisimilis GGS_124 DNA-entry nuclease YP_002996447.1 708160 D 486410 CDS YP_002996448.1 251782146 8111869 709309..710352 1 NC_012891.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily; phenylalanyl-tRNA synthetase subunit alpha 710352 pheS 8111869 pheS Streptococcus dysgalactiae subsp. equisimilis GGS_124 phenylalanyl-tRNA synthetase subunit alpha YP_002996448.1 709309 D 486410 CDS YP_002996449.1 251782147 8111290 710547..712967 1 NC_012891.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily; phenylalanyl-tRNA synthetase subunit beta 712967 pheT 8111290 pheT Streptococcus dysgalactiae subsp. equisimilis GGS_124 phenylalanyl-tRNA synthetase subunit beta YP_002996449.1 710547 D 486410 CDS YP_002996450.1 251782148 8111291 713041..713454 1 NC_012891.1 similar to salt-stress induced protein [Streptococcus pyogenes MGAS10750]; salt-stress induced protein 713454 8111291 SDEG_0735 Streptococcus dysgalactiae subsp. equisimilis GGS_124 salt-stress induced protein YP_002996450.1 713041 D 486410 CDS YP_002996451.1 251782149 8112279 713447..713683 1 NC_012891.1 similar to hypothetical protein MGAS10750 Spy0675 [Streptococcus pyogenes MGAS10750]; hypothetical protein 713683 8112279 SDEG_0736 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996451.1 713447 D 486410 CDS YP_002996452.1 251782150 8112280 713662..713832 1 NC_012891.1 similar to hypothetical protein spyM18 0830 [Streptococcus pyogenes MGAS8232]; hypothetical protein 713832 8112280 SDEG_0737 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996452.1 713662 D 486410 CDS YP_002996453.1 251782151 8112281 713905..714981 1 NC_012891.1 similar to ABC transporter permease protein [Streptococcus pyogenes MGAS10270]; ABC transporter permease 714981 8112281 SDEG_0738 Streptococcus dysgalactiae subsp. equisimilis GGS_124 ABC transporter permease YP_002996453.1 713905 D 486410 CDS YP_002996454.1 251782152 8112282 714988..715659 1 NC_012891.1 similar to ABC transporter ATP-binding protein [Streptococcus pyogenes MGAS6180]; ABC transporter ATP-binding protein 715659 8112282 SDEG_0739 Streptococcus dysgalactiae subsp. equisimilis GGS_124 ABC transporter ATP-binding protein YP_002996454.1 714988 D 486410 CDS YP_002996455.1 251782153 8112283 complement(715753..716664) 1 NC_012891.1 similar to neutral zinc metallopeptidase family [Streptococcus pyogenes MGAS10394]; neutral zinc metallopeptidase family 716664 8112283 SDEG_0740 Streptococcus dysgalactiae subsp. equisimilis GGS_124 neutral zinc metallopeptidase family YP_002996455.1 715753 R 486410 CDS YP_002996456.1 251782154 8112284 716839..720063 1 NC_012891.1 similar to ATP-dependent nuclease subunit B [Streptococcus pyogenes MGAS5005]; ATP-dependent nuclease subunit B 720063 rexB 8112284 rexB Streptococcus dysgalactiae subsp. equisimilis GGS_124 ATP-dependent nuclease subunit B YP_002996456.1 716839 D 486410 CDS YP_002996457.1 251782155 8111044 720060..723692 1 NC_012891.1 similar to ATP-dependent nuclease subunit A [Streptococcus pyogenes MGAS10394]; ATP-dependent nuclease subunit A 723692 rexA 8111044 rexA Streptococcus dysgalactiae subsp. equisimilis GGS_124 ATP-dependent nuclease subunit A YP_002996457.1 720060 D 486410 CDS YP_002996458.1 251782156 8111043 723849..724967 1 NC_012891.1 associated with arginine deiminase pathway genes; probably functions in arginine catabolism; transaminase 724967 aspC 8111043 aspC Streptococcus dysgalactiae subsp. equisimilis GGS_124 transaminase YP_002996458.1 723849 D 486410 CDS YP_002996459.1 251782157 8112352 725089..725847 1 NC_012891.1 similar to arginine-binding protein [Streptococcus pyogenes MGAS2096]; arginine-binding protein 725847 8112352 SDEG_0744 Streptococcus dysgalactiae subsp. equisimilis GGS_124 arginine-binding protein YP_002996459.1 725089 D 486410 CDS YP_002996460.1 251782158 8112285 725937..726113 1 NC_012891.1 a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA; 30S ribosomal protein S21 726113 rpsU 8112285 rpsU Streptococcus dysgalactiae subsp. equisimilis GGS_124 30S ribosomal protein S21 YP_002996460.1 725937 D 486410 CDS YP_002996461.1 251782159 8110449 complement(726243..726617) 1 NC_012891.1 similar to large-conductance mechanosensitive channel [Streptococcus pyogenes MGAS5005]; large-conductance mechanosensitive channel 726617 mscL 8110449 mscL Streptococcus dysgalactiae subsp. equisimilis GGS_124 large-conductance mechanosensitive channel YP_002996461.1 726243 R 486410 CDS YP_002996462.1 251782160 8110942 726745..728559 1 NC_012891.1 synthesizes RNA primers at the replication forks; DNA primase 728559 dnaG 8110942 dnaG Streptococcus dysgalactiae subsp. equisimilis GGS_124 DNA primase YP_002996462.1 726745 D 486410 CDS YP_002996463.1 251782161 8111846 728568..729677 1 NC_012891.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; primary sigma factor of bacterium; RNA polymerase sigma factor RpoD 729677 rpoD 8111846 rpoD Streptococcus dysgalactiae subsp. equisimilis GGS_124 RNA polymerase sigma factor RpoD YP_002996463.1 728568 D 486410 CDS YP_002996464.1 251782162 8111092 730002..730340 1 NC_012891.1 similar to hypothetical cytosolic protein [Streptococcus pyogenes MGAS5005]; hypothetical protein 730340 8111092 SDEG_0749 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996464.1 730002 D 486410 CDS YP_002996465.1 251782163 8112286 730473..731327 1 NC_012891.1 similar to dTDP-4-dehydrorhamnose reductase [Streptococcus pyogenes MGAS10394]; dTDP-4-dehydrorhamnose reductase 731327 8112286 SDEG_0750 Streptococcus dysgalactiae subsp. equisimilis GGS_124 dTDP-4-dehydrorhamnose reductase YP_002996465.1 730473 D 486410 CDS YP_002996466.1 251782164 8112287 731446..732600 1 NC_012891.1 similar to alpha-(1,2)- rhamnosyltransferase[Streptococcus pyogenes MGAS5005]; alpha-(1,2)-rhamnosyltransferase 732600 rgpAc 8112287 rgpAc Streptococcus dysgalactiae subsp. equisimilis GGS_124 alpha-(1,2)-rhamnosyltransferase YP_002996466.1 731446 D 486410 CDS YP_002996467.1 251782165 8111046 732590..733522 1 NC_012891.1 similar to alpha-L-Rhaalpha-13-L- rhamnosyltransferase[Streptococcus pyogenes MGAS5005]; alpha-L-Rhaalpha-1,3-L-rhamnosyltransferase 733522 rgpBc 8111046 rgpBc Streptococcus dysgalactiae subsp. equisimilis GGS_124 alpha-L-Rhaalpha-1,3-L-rhamnosyltransferase YP_002996467.1 732590 D 486410 CDS YP_002996468.1 251782166 8111047 733525..734331 1 NC_012891.1 similar to polysaccharide ABC exporter membrane-spanning protein [Streptococcus thermophilus LMG 18311]; polysaccharide ABC exporter membrane-spanning protein 734331 rgpC 8111047 rgpC Streptococcus dysgalactiae subsp. equisimilis GGS_124 polysaccharide ABC exporter membrane-spanning protein YP_002996468.1 733525 D 486410 CDS YP_002996469.1 251782167 8111048 734331..735497 1 NC_012891.1 similar to ABC-type polysaccharide/polyolphosphatetransport system ATPase component [Streptococcus thermophilus LMD-9]; polysaccharide/polyolphosphate ABC transporter ATPase 735497 8111048 SDEG_0754 Streptococcus dysgalactiae subsp. equisimilis GGS_124 polysaccharide/polyolphosphate ABC transporter ATPase YP_002996469.1 734331 D 486410 CDS YP_002996470.1 251782168 8112288 735510..736793 1 NC_012891.1 similar to glycosyl transferase family protein [Anabaena variabilis ATCC29413]; hypothetical protein 736793 8112288 SDEG_0755 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996470.1 735510 D 486410 CDS YP_002996471.1 251782169 8112289 736808..738034 1 NC_012891.1 similar to glycosyl transferase [Leifsonia xyli subsp. xyli str. CTCB07]; hypothetical protein 738034 wbbX 8112289 wbbX Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996471.1 736808 D 486410 CDS YP_002996472.1 251782170 8111951 738027..739010 1 NC_012891.1 similar to rhamnosyltransferase [Leifsonia xyli subsp. xyli str. CTCB07]; rhamnosyltransferase 739010 8111951 SDEG_0757 Streptococcus dysgalactiae subsp. equisimilis GGS_124 rhamnosyltransferase YP_002996472.1 738027 D 486410 CDS YP_002996473.1 251782171 8112290 739020..740501 1 NC_012891.1 similar to hypothetical protein str1466 [Streptococcus thermophilus CNRZ1066]; hypothetical protein 740501 8112290 SDEG_0758 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996473.1 739020 D 486410 CDS YP_002996474.1 251782172 8112291 740546..741355 1 NC_012891.1 similar to glycosyltransferase involved in cell wall biogenesis [Streptococcus thermophilus LMD-9]; cell wall biosynthesis glycosyltransferase 741355 8112291 SDEG_0759 Streptococcus dysgalactiae subsp. equisimilis GGS_124 cell wall biosynthesis glycosyltransferase YP_002996474.1 740546 D 486410 CDS YP_002996475.1 251782173 8112292 741352..742047 1 NC_012891.1 similar to glycosyltransferase [Streptococcus equi subsp. zooepidemicus MGCS10565]; glycosyltransferase 742047 8112292 SDEG_0760 Streptococcus dysgalactiae subsp. equisimilis GGS_124 glycosyltransferase YP_002996475.1 741352 D 486410 CDS YP_002996476.1 251782174 8112293 742048..742404 1 NC_012891.1 lytic transglycosylase, dTDP-4-rhamnose reductase; similar to glycosyltransferase lytictransglycosylase dTDP-4-rhamnosereductase[Streptococcus equi subsp. zooepidemicus MGCS10565]; glycosyltransferase 742404 8112293 SDEG_0761 Streptococcus dysgalactiae subsp. equisimilis GGS_124 glycosyltransferase YP_002996476.1 742048 D 486410 CDS YP_002996477.1 251782175 8112294 742467..744938 1 NC_012891.1 similar to phosphoglycerol transferase [Streptococcusequi subsp. zooepidemicusMGCS10565]; phosphoglycerol transferase 744938 8112294 SDEG_0762 Streptococcus dysgalactiae subsp. equisimilis GGS_124 phosphoglycerol transferase YP_002996477.1 742467 D 486410 CDS YP_002996478.1 251782176 8112295 745121..746137 1 NC_012891.1 similar to UDP-glucose 4-epimerase GalE [Streptococcus equi subsp. zooepidemicus MGCS10565]; UDP-glucose 4-epimerase 746137 galE 8112295 galE Streptococcus dysgalactiae subsp. equisimilis GGS_124 UDP-glucose 4-epimerase YP_002996478.1 745121 D 486410 CDS YP_002996479.1 251782177 8111983 746258..747511 1 NC_012891.1 similar to AmrA [Streptococcus pyogenes MGAS10394]; transcriptional activator 747511 amrA 8111983 amrA Streptococcus dysgalactiae subsp. equisimilis GGS_124 transcriptional activator YP_002996479.1 746258 D 486410 CDS YP_002996480.1 251782178 8112322 747691..748914 1 NC_012891.1 catalyzes the release of the N-terminal amino acid from a tripeptide; peptidase T 748914 pepT 8112322 pepT Streptococcus dysgalactiae subsp. equisimilis GGS_124 peptidase T YP_002996480.1 747691 D 486410 CDS YP_002996481.1 251782179 8111280 748958..749446 1 NC_012891.1 similar to pore forming protein EbsA [Streptococcus pyogenes MGAS10750]; pore forming protein 749446 ebsA 8111280 ebsA Streptococcus dysgalactiae subsp. equisimilis GGS_124 pore forming protein YP_002996481.1 748958 D 486410 CDS YP_002996482.1 251782180 8111863 complement(749433..749630) 1 NC_012891.1 similar to ferredoxin [Streptococcus pyogenes MGAS10750]; ferredoxin 749630 8111863 SDEG_0767 Streptococcus dysgalactiae subsp. equisimilis GGS_124 ferredoxin YP_002996482.1 749433 R 486410 CDS YP_002996483.1 251782181 8112296 749678..750157 1 NC_012891.1 similar to hypothetical protein SPs1318 [Streptococcus pyogenes SSI-1]; hypothetical protein 750157 8112296 SDEG_0768 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996483.1 749678 D 486410 CDS YP_002996484.1 251782182 8112297 750172..750852 1 NC_012891.1 Catalyzes the formation of (d)CDP from ATP and (d)CMP; cytidylate kinase 750852 cmk 8112297 cmk Streptococcus dysgalactiae subsp. equisimilis GGS_124 cytidylate kinase YP_002996484.1 750172 D 486410 CDS YP_002996485.1 251782183 8111627 751014..751544 1 NC_012891.1 IF-3 has several functions that are required and promote translation initiation including; preventing association of 70S by binding to 30S; monitoring codon-anticodon interactions by promoting disassociation of fMet-tRNA(fMet) from initiation complexes formed on leaderless mRNAs or incorrectly bound noninitiatior tRNAs and complexes with noncanonical start sites; stimulates codon-anticodon interactions at P-site; involved in moving mRNA to the P-site; and in recycling subunits; translation initiation factor IF-3 751544 infC 8111627 infC Streptococcus dysgalactiae subsp. equisimilis GGS_124 translation initiation factor IF-3 YP_002996485.1 751014 D 486410 CDS YP_002996486.1 251782184 8112053 751585..751782 1 NC_012891.1 similar to 50S ribosomal protein L35 [Streptococcus pyogenes MGAS8232]; 50S ribosomal protein L35 751782 rpmI 8112053 rpmI Streptococcus dysgalactiae subsp. equisimilis GGS_124 50S ribosomal protein L35 YP_002996486.1 751585 D 486410 CDS YP_002996487.1 251782185 8111087 751841..752200 1 NC_012891.1 binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit; 50S ribosomal protein L20 752200 rplT 8111087 rplT Streptococcus dysgalactiae subsp. equisimilis GGS_124 50S ribosomal protein L20 YP_002996487.1 751841 D 486410 CDS YP_002996488.1 251782186 8111073 complement(752485..754713) 1 NC_012891.1 similar to phosphoglycerol transferase [Streptococcus pyogenes MGAS10394]; phosphoglycerol transferase 754713 8111073 SDEG_0773 Streptococcus dysgalactiae subsp. equisimilis GGS_124 phosphoglycerol transferase YP_002996488.1 752485 R 486410 CDS YP_002996489.1 251782187 8110367 754815..755978 1 NC_012891.1 similar to methyltransferase [Streptococcus pyogenes MGAS5005]; methyltransferase 755978 8110367 SDEG_0774 Streptococcus dysgalactiae subsp. equisimilis GGS_124 methyltransferase YP_002996489.1 754815 D 486410 CDS YP_002996490.1 251782188 8110368 755975..756661 1 NC_012891.1 catalyzes the dehydration of 3-dehydroquinate to form 3-dehydroshikimate in aromatic amino acid biosynthesis; 3-dehydroquinate dehydratase 756661 aroD 8110368 aroD Streptococcus dysgalactiae subsp. equisimilis GGS_124 3-dehydroquinate dehydratase YP_002996490.1 755975 D 486410 CDS YP_002996491.1 251782189 8112340 756759..757925 1 NC_012891.1 catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis; chorismate synthase 757925 aroF 8112340 aroF Streptococcus dysgalactiae subsp. equisimilis GGS_124 chorismate synthase YP_002996491.1 756759 D 486410 CDS YP_002996492.1 251782190 8112342 757987..758328 1 NC_012891.1 similar to hypothetical cytosolic protein [Streptococcus pyogenes MGAS10750]; hypothetical protein 758328 8112342 SDEG_0777 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996492.1 757987 D 486410 CDS YP_002996493.1 251782191 8110369 758541..759902 1 NC_012891.1 catalyzes the reduction of 2 glutathione to glutathione disulfide; maintains high levels of reduced glutathione in the cytosol; involved in redox regulation and oxidative defense; glutathione reductase 759902 gor 8110369 gor Streptococcus dysgalactiae subsp. equisimilis GGS_124 glutathione reductase YP_002996493.1 758541 D 486410 CDS YP_002996494.1 251782192 8112016 complement(759990..761261) 1 NC_012891.1 similar to dihydrofolate synthase [Streptococcus pyogenes MGAS10394]; dihydrofolate synthase 761261 8112016 SDEG_0779 Streptococcus dysgalactiae subsp. equisimilis GGS_124 dihydrofolate synthase YP_002996494.1 759990 R 486410 CDS YP_002996495.1 251782193 8110370 complement(761309..761749) 1 NC_012891.1 similar to hypothetical protein spyM18 0877 [Streptococcus pyogenes MGAS8232]; hypothetical protein 761749 8110370 SDEG_0780 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996495.1 761309 R 486410 CDS YP_002996496.1 251782194 8110371 761985..763127 1 NC_012891.1 similar to cysteine desulfurase / selenocysteine lyase [Streptococcus pyogenes MGAS10270]; cysteine desulfurase/selenocysteine lyase 763127 nifS1 8110371 nifS1 Streptococcus dysgalactiae subsp. equisimilis GGS_124 cysteine desulfurase/selenocysteine lyase YP_002996496.1 761985 D 486410 CDS YP_002996497.1 251782195 8111711 763129..764343 1 NC_012891.1 Required for the synthesis of the thiazole moiety; thiamine biosynthesis protein ThiI 764343 thiI 8111711 thiI Streptococcus dysgalactiae subsp. equisimilis GGS_124 thiamine biosynthesis protein ThiI YP_002996497.1 763129 D 486410 CDS YP_002996498.1 251782196 8110517 764522..765676 1 NC_012891.1 similar to capsule biosynthesis protein [Streptococcus pyogenes MGAS5005]; capsule biosynthesis protein 765676 capA 8110517 capA Streptococcus dysgalactiae subsp. equisimilis GGS_124 capsule biosynthesis protein YP_002996498.1 764522 D 486410 CDS YP_002996499.1 251782197 8111601 765790..766818 1 NC_012891.1 similar to transposase [Streptococcus pyogenes MGAS10270]; transposase 766818 8111601 SDEG_0784 Streptococcus dysgalactiae subsp. equisimilis GGS_124 transposase YP_002996499.1 765790 D 486410 CDS YP_002996500.1 251782198 8110372 complement(766922..767341) 1 NC_012891.1 similar to ribosomal protein L21 [Streptococcus agalactiae CJB111]; 50S ribosomal protein L21 767341 rplU 8110372 rplU Streptococcus dysgalactiae subsp. equisimilis GGS_124 50S ribosomal protein L21 YP_002996500.1 766922 R 486410 CDS YP_002996501.1 251782199 8111074 767066..767380 1 NC_012891.1 similar to 50S ribosomal protein L21 [Streptococcus pyogenes MGAS5005]; 50S ribosomal protein L21 767380 rplU 8111074 rplU Streptococcus dysgalactiae subsp. equisimilis GGS_124 50S ribosomal protein L21 YP_002996501.1 767066 D 486410 CDS YP_002996502.1 251782200 8111075 767392..767718 1 NC_012891.1 similar to hypothetical protein spyM18 0884 [Streptococcus pyogenes MGAS8232]; hypothetical protein 767718 8111075 SDEG_0787 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996502.1 767392 D 486410 CDS YP_002996503.1 251782201 8110373 767746..768039 1 NC_012891.1 involved in the peptidyltransferase reaction during translation; 50S ribosomal protein L27 768039 rpmA 8110373 rpmA Streptococcus dysgalactiae subsp. equisimilis GGS_124 50S ribosomal protein L27 YP_002996503.1 767746 D 486410 CDS YP_002996504.1 251782202 8111079 768287..769201 1 NC_012891.1 similar to transcriptional regulator; LysR family transcriptional regulator 769201 8111079 SDEG_0789 Streptococcus dysgalactiae subsp. equisimilis GGS_124 LysR family transcriptional regulator YP_002996504.1 768287 D 486410 CDS YP_002996505.1 251782203 8110374 769198..769656 1 NC_012891.1 lipoprotein signal peptidase; integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis; lipoprotein signal peptidase 769656 lsp 8110374 lsp Streptococcus dysgalactiae subsp. equisimilis GGS_124 lipoprotein signal peptidase YP_002996505.1 769198 D 486410 CDS YP_002996506.1 251782204 8110911 769646..770539 1 NC_012891.1 similar to ribosomal large subunit pseudouridine synthase D [Streptococcus pyogenes MGAS5005]; ribosomal large subunit pseudouridine synthase D 770539 8110911 SDEG_0791 Streptococcus dysgalactiae subsp. equisimilis GGS_124 ribosomal large subunit pseudouridine synthase D YP_002996506.1 769646 D 486410 CDS YP_002996507.1 251782205 8110375 complement(770666..771340) 1 NC_012891.1 similar to membrane-associated alkaline phosphatase [Streptococcus equi subsp. zooepidemicus MGCS10565]; membrane-associated alkaline phosphatase 771340 8110375 SDEG_0792 Streptococcus dysgalactiae subsp. equisimilis GGS_124 membrane-associated alkaline phosphatase YP_002996507.1 770666 R 486410 CDS YP_002996508.1 251782206 8110376 771559..772080 1 NC_012891.1 regulates pyrimidine biosynthesis by binding to the mRNA of the pyr genes, also has been shown to have uracil phosphoribosyltransferase activity; bifunctional pyrimidine regulatory protein PyrR/uracil phosphoribosyltransferase 772080 pyrR 8110376 pyrR Streptococcus dysgalactiae subsp. equisimilis GGS_124 bifunctional pyrimidine regulatory protein PyrR/uracil phosphoribosyltransferase YP_002996508.1 771559 D 486410 CDS YP_002996509.1 251782207 8111346 772096..773355 1 NC_012891.1 similar to uracil permease [Streptococcus pyogenes MGAS10270]; uracil permease 773355 pyrP 8111346 pyrP Streptococcus dysgalactiae subsp. equisimilis GGS_124 uracil permease YP_002996509.1 772096 D 486410 CDS YP_002996510.1 251782208 8111338 774383..775474 1 NC_012891.1 catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers; carbamoyl phosphate synthase small subunit 775474 carA 8111338 carA Streptococcus dysgalactiae subsp. equisimilis GGS_124 carbamoyl phosphate synthase small subunit YP_002996510.1 774383 D 486410 CDS YP_002996511.1 251782209 8111602 775726..778902 1 NC_012891.1 four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate; CarB is responsible for the amidotransferase activity; carbamoyl phosphate synthase large subunit 778902 carB 8111602 carB Streptococcus dysgalactiae subsp. equisimilis GGS_124 carbamoyl phosphate synthase large subunit YP_002996511.1 775726 D 486410 CDS YP_002996512.1 251782210 8111603 779124..780386 1 NC_012891.1 similar to periplasmic component of efflux system [Streptococcus pyogenes MGAS10750]; periplasmic protein of efflux system 780386 8111603 SDEG_0798 Streptococcus dysgalactiae subsp. equisimilis GGS_124 periplasmic protein of efflux system YP_002996512.1 779124 D 486410 CDS YP_002996513.1 251782211 8110377 780386..781096 1 NC_012891.1 similar to ABC transporter ATP-binding protein [Streptococcus pyogenes MGAS6180]; ABC transporter ATP-binding protein 781096 8110377 SDEG_0799 Streptococcus dysgalactiae subsp. equisimilis GGS_124 ABC transporter ATP-binding protein YP_002996513.1 780386 D 486410 CDS YP_002996514.1 251782212 8110378 781108..782328 1 NC_012891.1 similar to ABC transporter permease protein [Streptococcus pyogenes MGAS5005]; ABC transporter permease 782328 8110378 SDEG_0800 Streptococcus dysgalactiae subsp. equisimilis GGS_124 ABC transporter permease YP_002996514.1 781108 D 486410 CDS YP_002996515.1 251782213 8110379 782321..782938 1 NC_012891.1 similar to hypothetical protein Sez 1119 [Streptococcus equi subsp. zooepidemicus MGCS10565]; hypothetical protein 782938 8110379 SDEG_0801 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996515.1 782321 D 486410 CDS YP_002996516.1 251782214 8110380 783013..784755 1 NC_012891.1 similar to glycerophosphoryl diester phosphodiesterase [Streptococcus pyogenes MGAS6180]; glycerophosphoryl diester phosphodiesterase 784755 8110380 SDEG_0802 Streptococcus dysgalactiae subsp. equisimilis GGS_124 glycerophosphoryl diester phosphodiesterase YP_002996516.1 783013 D 486410 CDS YP_002996517.1 251782215 8110381 784873..785154 1 NC_012891.1 binds to lower part of 30S body where it stabilizes two domains; required for efficient assembly of 30S; in Escherichia coli this protein has nuclease activity; 30S ribosomal protein S16 785154 rpsP 8110381 rpsP Streptococcus dysgalactiae subsp. equisimilis GGS_124 30S ribosomal protein S16 YP_002996517.1 784873 D 486410 CDS YP_002996518.1 251782216 8111108 785164..785403 1 NC_012891.1 similar to hypothetical protein spyM18 0901 [Streptococcus pyogenes MGAS8232]; hypothetical protein 785403 8111108 SDEG_0804 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996518.1 785164 D 486410 CDS YP_002996519.1 251782217 8110382 785669..787126 1 NC_012891.1 similar to cell wall surface anchor family protein [Streptococcus equi subsp. zooepidemicus MGCS10565]; cell wall surface anchor family protein 787126 8110382 SDEG_0805 Streptococcus dysgalactiae subsp. equisimilis GGS_124 cell wall surface anchor family protein YP_002996519.1 785669 D 486410 CDS YP_002996520.1 251782218 8110383 787495..788013 1 NC_012891.1 Essential for efficient processing of 16S rRNA; 16S rRNA-processing protein RimM 788013 rimM 8110383 rimM Streptococcus dysgalactiae subsp. equisimilis GGS_124 16S rRNA-processing protein RimM YP_002996520.1 787495 D 486410 CDS YP_002996521.1 251782219 8111050 788003..788734 1 NC_012891.1 methylates guanosine-37 in various tRNAs; uses S-adenosyl-L-methionine to transfer methyl group to tRNA; tRNA (guanine-N(1)-)-methyltransferase 788734 trmD 8111050 trmD Streptococcus dysgalactiae subsp. equisimilis GGS_124 tRNA (guanine-N(1)-)-methyltransferase YP_002996521.1 788003 D 486410 CDS YP_002996522.1 251782220 8111926 788734..789726 1 NC_012891.1 similar to thioredoxin reductase [Streptococcus pyogenes MGAS5005]; thioredoxin reductase 789726 trxB 8111926 trxB Streptococcus dysgalactiae subsp. equisimilis GGS_124 thioredoxin reductase YP_002996522.1 788734 D 486410 CDS YP_002996523.1 251782221 8111934 789915..790973 1 NC_012891.1 similar to regulatory protein [Streptococcus pyogenes MGAS5005]; regulatory protein 790973 8111934 SDEG_0809 Streptococcus dysgalactiae subsp. equisimilis GGS_124 regulatory protein YP_002996523.1 789915 D 486410 CDS YP_002996524.1 251782222 8110384 790986..791909 1 NC_012891.1 ketopantoate reductase; catalyzes the NADPH reduction of ketopantoate to pantoate; functions in pantothenate (vitamin B5) biosynthesis; 2-dehydropantoate 2-reductase 791909 apbA 8110384 apbA Streptococcus dysgalactiae subsp. equisimilis GGS_124 2-dehydropantoate 2-reductase YP_002996524.1 790986 D 486410 CDS YP_002996525.1 251782223 8112327 792144..792857 1 NC_012891.1 similar to DeoR family regulatory protein [Streptococcus pyogenes str. Manfredo]; fructose repressor 792857 8112327 SDEG_0811 Streptococcus dysgalactiae subsp. equisimilis GGS_124 fructose repressor YP_002996525.1 792144 D 486410 CDS YP_002996526.1 251782224 8110385 792854..793765 1 NC_012891.1 similar to 1-phosphofructokinase [Streptococcus pyogenes MGAS10270]; 1-phosphofructokinase 793765 fruB 8110385 fruB Streptococcus dysgalactiae subsp. equisimilis GGS_124 1-phosphofructokinase YP_002996526.1 792854 D 486410 CDS YP_002996527.1 251782225 8111911 793762..795708 1 NC_012891.1 similar to PTS system fructose-specific II ABC component [Streptococcus pyogenes MGAS2096]; PTS system fructose-specific transporter subunit IIABC 795708 fruA 8111911 fruA Streptococcus dysgalactiae subsp. equisimilis GGS_124 PTS system fructose-specific transporter subunit IIABC YP_002996527.1 793762 D 486410 CDS YP_002996528.1 251782226 8111910 795790..796398 1 NC_012891.1 similar to autolysin [Streptococcus pyogenes MGAS5005]; autolysin 796398 mur1-1 8111910 mur1-1 Streptococcus dysgalactiae subsp. equisimilis GGS_124 autolysin YP_002996528.1 795790 D 486410 CDS YP_002996529.1 251782227 8111680 796558..797265 1 NC_012891.1 similar to N-acetylmuramidase [Streptococcus pyogenes MGAS10270]; N-acetylmuramidase 797265 mur1-2 8111680 mur1-2 Streptococcus dysgalactiae subsp. equisimilis GGS_124 N-acetylmuramidase YP_002996529.1 796558 D 486410 CDS YP_002996530.1 251782228 8111681 797316..797837 1 NC_012891.1 similar to hypothetical protein SAG1344 [Streptococcus agalactiae 2603V/R]; hypothetical protein 797837 8111681 SDEG_0816 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996530.1 797316 D 486410 CDS YP_002996531.1 251782229 8110386 797876..798289 1 NC_012891.1 similar to transposase [Streptococcus pyogenes MGAS10394]; transposase 798289 8110386 SDEG_0817 Streptococcus dysgalactiae subsp. equisimilis GGS_124 transposase YP_002996531.1 797876 D 486410 CDS YP_002996532.1 251782230 8110387 798289..799137 1 NC_012891.1 similar to DegV family protein [Streptococcus pyogenes MGAS10750]; DegV family protein 799137 8110387 SDEG_0818 Streptococcus dysgalactiae subsp. equisimilis GGS_124 DegV family protein YP_002996532.1 798289 D 486410 CDS YP_002996533.1 251782231 8110388 799257..800465 1 NC_012891.1 catalyzes the addition and repair of the 3'-terminal CCA sequence in tRNA; these proteins belong to the CCA-adding enzyme subfamily 2 which does not have phosphohydrolase activity; tRNA CCA-pyrophosphorylase 800465 papS 8110388 papS Streptococcus dysgalactiae subsp. equisimilis GGS_124 tRNA CCA-pyrophosphorylase YP_002996533.1 799257 D 486410 CDS YP_002996534.1 251782232 8111750 800462..802339 1 NC_012891.1 similar to ABC transporter ATP-binding protein uup [Streptococcus pyogenes MGAS5005]; ABC transporter ATP-binding protein 802339 8111750 SDEG_0820 Streptococcus dysgalactiae subsp. equisimilis GGS_124 ABC transporter ATP-binding protein YP_002996534.1 800462 D 486410 CDS YP_002996535.1 251782233 8110389 802447..804192 1 NC_012891.1 similar to ABC transporter ATP-binding /permease protein [Streptococcus equi subsp. zooepidemicus MGCS10565]; ABC transporter ATP-binding protein/permease 804192 8110389 SDEG_0821 Streptococcus dysgalactiae subsp. equisimilis GGS_124 ABC transporter ATP-binding protein/permease YP_002996535.1 802447 D 486410 CDS YP_002996536.1 251782234 8110390 804192..805964 1 NC_012891.1 similar to ABC transporter ATP-binding /permease protein [Streptococcusequi subsp.zooepidemicus MGCS10565]; ABC transporter ATP-binding protein/permease 805964 8110390 SDEG_0822 Streptococcus dysgalactiae subsp. equisimilis GGS_124 ABC transporter ATP-binding protein/permease YP_002996536.1 804192 D 486410 CDS YP_002996537.1 251782235 8110391 806154..807503 1 NC_012891.1 converts 2-oxoglutarate to glutamate; in Escherichia coli this enzyme plays a role in glutamate synthesis when the cell is under energy restriction; uses NADPH; forms a homohexamer; glutamate dehydrogenase 807503 gdh 8110391 gdh Streptococcus dysgalactiae subsp. equisimilis GGS_124 glutamate dehydrogenase YP_002996537.1 806154 D 486410 CDS YP_002996538.1 251782236 8111990 807628..808038 1 NC_012891.1 cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+); peptide deformylase 808038 fms 8111990 fms Streptococcus dysgalactiae subsp. equisimilis GGS_124 peptide deformylase YP_002996538.1 807628 D 486410 CDS YP_002996539.1 251782237 8111899 complement(808226..810250) 1 NC_012891.1 similar to cell surface 5'-nucleotidase [Streptococcus equi subsp. zooepidemicus MGCS10565]; cell surface 5'-nucleotidase 810250 8111899 SDEG_0825 Streptococcus dysgalactiae subsp. equisimilis GGS_124 cell surface 5'-nucleotidase YP_002996539.1 808226 R 486410 CDS YP_002996540.1 251782238 8110392 810469..810927 1 NC_012891.1 similar to GTP pyrophosphokinase [Streptococcus pyogenes MGAS5005]; GTP pyrophosphokinase 810927 8110392 SDEG_0826 Streptococcus dysgalactiae subsp. equisimilis GGS_124 GTP pyrophosphokinase YP_002996540.1 810469 D 486410 CDS YP_002996541.1 251782239 8110393 810930..811118 1 NC_012891.1 similar to GTP pyrophosphokinase [Streptococcus pyogenes MGAS10750]; GTP pyrophosphokinase 811118 8110393 SDEG_0827 Streptococcus dysgalactiae subsp. equisimilis GGS_124 GTP pyrophosphokinase YP_002996541.1 810930 D 486410 CDS YP_002996542.1 251782240 8110394 811121..811789 1 NC_012891.1 similar to two-component response regulator [Streptococcus pyogenes MGAS5005]; two-component response regulator 811789 sptR 8110394 sptR Streptococcus dysgalactiae subsp. equisimilis GGS_124 two-component response regulator YP_002996542.1 811121 D 486410 CDS YP_002996543.1 251782241 8110499 811771..813030 1 NC_012891.1 similar to two component system histidine kinase [Streptococcus pyogenes MGAS6180]; two component system histidine kinase 813030 sptS 8110499 sptS Streptococcus dysgalactiae subsp. equisimilis GGS_124 two component system histidine kinase YP_002996543.1 811771 D 486410 CDS YP_002996544.1 251782242 8110395 814533..816338 1 NC_012891.1 similar to ABC-type multidrug transportsystem ATPas and permease component[Streptococcus suis 98HAH33]; ATPase and permease component 816338 8110395 SDEG_0831 Streptococcus dysgalactiae subsp. equisimilis GGS_124 ATPase and permease component YP_002996544.1 814533 D 486410 CDS YP_002996545.1 251782243 8110396 816340..818082 1 NC_012891.1 similar to ABC transporter ATP-binding /permease protein [Streptococcus equi subsp. zooepidemicus MGCS10565]; ABC transporter ATP-binding protein/permease 818082 8110396 SDEG_0832 Streptococcus dysgalactiae subsp. equisimilis GGS_124 ABC transporter ATP-binding protein/permease YP_002996545.1 816340 D 486410 CDS YP_002996546.1 251782244 8110397 818287..819165 1 NC_012891.1 similar to mevalonate kinase [Streptococcus pyogenes MGAS10270]; mevalonate kinase 819165 mvaK1 8110397 mvaK1 Streptococcus dysgalactiae subsp. equisimilis GGS_124 mevalonate kinase YP_002996546.1 818287 D 486410 CDS YP_002996547.1 251782245 8111700 819147..820091 1 NC_012891.1 similar to diphosphomevalonate decarboxylase [Streptococcus pyogenes MGAS10394]; diphosphomevalonate decarboxylase 820091 mvaD 8111700 mvaD Streptococcus dysgalactiae subsp. equisimilis GGS_124 diphosphomevalonate decarboxylase YP_002996547.1 819147 D 486410 CDS YP_002996548.1 251782246 8111699 820036..821097 1 NC_012891.1 similar to phosphomevalonate kinase [Streptococcus pyogenes MGAS10270]; phosphomevalonate kinase 821097 mvaK2 8111699 mvaK2 Streptococcus dysgalactiae subsp. equisimilis GGS_124 phosphomevalonate kinase YP_002996548.1 820036 D 486410 CDS YP_002996549.1 251782247 8111701 821084..822076 1 NC_012891.1 catalyzes the isomerization of isopentenyl pyrophosphate to dimethylallyl diphosphate; isopentenyl pyrophosphate isomerase 822076 8111701 SDEG_0836 Streptococcus dysgalactiae subsp. equisimilis GGS_124 isopentenyl pyrophosphate isomerase YP_002996549.1 821084 D 486410 CDS YP_002996550.1 251782248 8110398 complement(822490..823749) 1 NC_012891.1 similar to transcriptional regulatorp utative [Streptococcus pneumoniae TIGR4]; transcriptional regulator 823749 8110398 SDEG_0837 Streptococcus dysgalactiae subsp. equisimilis GGS_124 transcriptional regulator YP_002996550.1 822490 R 486410 CDS YP_002996551.1 251782249 8110399 825449..826477 1 NC_012891.1 similar to transposase [Streptococcus pyogenes MGAS10270]; transposase 826477 8110399 SDEG_0838 Streptococcus dysgalactiae subsp. equisimilis GGS_124 transposase YP_002996551.1 825449 D 486410 CDS YP_002996552.1 251782250 8110400 826602..827531 1 NC_012891.1 similar to hypothetical protein lin1204 [Listeria innocua Clip11262]; hypothetical protein 827531 8110400 SDEG_0839 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996552.1 826602 D 486410 CDS YP_002996553.1 251782251 8110401 827723..828526 1 NC_012891.1 similar to fibronectin-binding protein [Streptococcus equi subsp. zooepidemicus]; hypothetical protein 828526 8110401 SDEG_0840 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996553.1 827723 D 486410 CDS YP_002996554.1 251782252 8110402 complement(829360..830904) 1 NC_012891.1 similar to transcriptional regulator [Streptococcus pneumoniae TIGR4]; transcriptional regulator 830904 8110402 SDEG_0841 Streptococcus dysgalactiae subsp. equisimilis GGS_124 transcriptional regulator YP_002996554.1 829360 R 486410 CDS YP_002996555.1 251782253 8110403 complement(831065..832342) 1 NC_012891.1 similar to HMG-CoA reductase [Streptococcus pyogenes MGAS8232]; HMG-CoA reductase 832342 mvaS1 8110403 mvaS1 Streptococcus dysgalactiae subsp. equisimilis GGS_124 HMG-CoA reductase YP_002996555.1 831065 R 486410 CDS YP_002996556.1 251782254 8111702 complement(832323..833504) 1 NC_012891.1 similar to HMG-CoA synthase [Streptococcus pyogenes MGAS8232]; HMG-CoA synthase 833504 mvaS2 8111702 mvaS2 Streptococcus dysgalactiae subsp. equisimilis GGS_124 HMG-CoA synthase YP_002996556.1 832323 R 486410 CDS YP_002996557.1 251782255 8111703 complement(833692..834720) 1 NC_012891.1 similar to transposase [Streptococcus pyogenes MGAS10270]; transposase 834720 8111703 SDEG_0844 Streptococcus dysgalactiae subsp. equisimilis GGS_124 transposase YP_002996557.1 833692 R 486410 CDS YP_002996558.1 251782256 8110404 834893..835738 1 NC_012891.1 ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived; thymidylate synthase 835738 thyA 8110404 thyA Streptococcus dysgalactiae subsp. equisimilis GGS_124 thymidylate synthase YP_002996558.1 834893 D 486410 CDS YP_002996559.1 251782257 8110522 835819..836316 1 NC_012891.1 similar to dihydrofolate reductase [Streptococcus pyogenes MGAS5005]; dihydrofolate reductase 836316 dyr 8110522 dyr Streptococcus dysgalactiae subsp. equisimilis GGS_124 dihydrofolate reductase YP_002996559.1 835819 D 486410 CDS YP_002996560.1 251782258 8111862 836336..836506 1 NC_012891.1 similar to hypothetical protein Sez 1076 [Streptococcus equisubsp. zooepidemicus MGCS10565]; hypothetical protein 836506 8111862 SDEG_0847 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996560.1 836336 D 486410 CDS YP_002996561.1 251782259 8110405 836620..837849 1 NC_012891.1 binds and unfolds substrates as part of the ClpXP protease; ATP-dependent protease ATP-binding subunit ClpX 837849 clpX 8110405 clpX Streptococcus dysgalactiae subsp. equisimilis GGS_124 ATP-dependent protease ATP-binding subunit ClpX YP_002996561.1 836620 D 486410 CDS YP_002996562.1 251782260 8111625 837859..838458 1 NC_012891.1 binds guanine nucleotides; in Escherichia coli depletion results in defective cell division and filamentation; in Bacillus subtilis this gene is essential; ribosome biogenesis GTP-binding protein YsxC 838458 engB 8111625 engB Streptococcus dysgalactiae subsp. equisimilis GGS_124 ribosome biogenesis GTP-binding protein YsxC YP_002996562.1 837859 D 486410 CDS YP_002996563.1 251782261 8110406 838602..839345 1 NC_012891.1 similar to hypothetical protein MGAS10270 Spy0751 [Streptococcus pyogenes MGAS10270]; hypothetical protein 839345 8110406 SDEG_0850 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996563.1 838602 D 486410 CDS YP_002996564.1 251782262 8110407 complement(839402..841501) 1 NC_012891.1 similar to ATP-dependentprotease ATP-binding subunit ClpL [Streptococcus equi subsp.zooepidemicusMGCS10565]; ATP-dependentprotease ATP-binding subunit 841501 clpL 8110407 clpL Streptococcus dysgalactiae subsp. equisimilis GGS_124 ATP-dependentprotease ATP-binding subunit YP_002996564.1 839402 R 486410 CDS YP_002996565.1 251782263 8111623 complement(841774..842637) 1 NC_012891.1 similar to transposase [Streptococcus pyogenes MGAS2096]; transposase 842637 8111623 SDEG_0852 Streptococcus dysgalactiae subsp. equisimilis GGS_124 transposase YP_002996565.1 841774 R 486410 CDS YP_002996566.1 251782264 8110408 843825..844373 1 NC_012891.1 binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit; 50S ribosomal protein L10 844373 rplJ 8110408 rplJ Streptococcus dysgalactiae subsp. equisimilis GGS_124 50S ribosomal protein L10 YP_002996566.1 843825 D 486410 CDS YP_002996567.1 251782265 8111065 complement(844419..844793) 1 NC_012891.1 similar to hypothetical protein spyM18 1050 [Streptococcus pyogenes MGAS8232]; hypothetical protein 844793 8111065 SDEG_0854 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996567.1 844419 R 486410 CDS YP_002996568.1 251782266 8110409 844423..844803 1 NC_012891.1 present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulates GTPase activity of translation factors; 50S ribosomal protein L7/L12 844803 rplL 8110409 rplL Streptococcus dysgalactiae subsp. equisimilis GGS_124 50S ribosomal protein L7/L12 YP_002996568.1 844423 D 486410 CDS YP_002996569.1 251782267 8111067 845043..846278 1 NC_012891.1 similar to DD-carboxypeptidase penicillin-binding protein [Streptococcus pyogenes MGAS8232]; carboxypeptidase, penicillin-binding protein 846278 8111067 SDEG_0856 Streptococcus dysgalactiae subsp. equisimilis GGS_124 carboxypeptidase, penicillin-binding protein YP_002996569.1 845043 D 486410 CDS YP_002996570.1 251782268 8110410 complement(846369..847331) 1 NC_012891.1 similar to polysaccharide deacetylase [Streptococcus pyogenes MGAS2096]; polysaccharide deacetylase 847331 8110410 SDEG_0857 Streptococcus dysgalactiae subsp. equisimilis GGS_124 polysaccharide deacetylase YP_002996570.1 846369 R 486410 CDS YP_002996571.1 251782269 8110411 847515..848801 1 NC_012891.1 similar to homoserine dehydrogenase [Streptococcus suis 89/1591]; homoserine dehydrogenase 848801 8110411 SDEG_0858 Streptococcus dysgalactiae subsp. equisimilis GGS_124 homoserine dehydrogenase YP_002996571.1 847515 D 486410 CDS YP_002996572.1 251782270 8110412 848803..849663 1 NC_012891.1 similar to homoserine kinase [Streptococcus pneumoniae D39]; homoserine kinase 849663 thrB 8110412 thrB Streptococcus dysgalactiae subsp. equisimilis GGS_124 homoserine kinase YP_002996572.1 848803 D 486410 CDS YP_002996573.1 251782271 8110520 849723..851045 1 NC_012891.1 similar to folylpolyglutamate synthase / dihydrofolate synthase [Streptococcus pyogenes MGAS10270]; bifunctional folylpolyglutamate synthase/dihydrofolate synthase 851045 folC1 8110520 folC1 Streptococcus dysgalactiae subsp. equisimilis GGS_124 bifunctional folylpolyglutamate synthase/dihydrofolate synthase YP_002996573.1 849723 D 486410 CDS YP_002996574.1 251782272 8111902 851085..851651 1 NC_012891.1 involved in the first step of tetrahydrofolate biosynthesis; catalyzes the formation of formate and 2-amino-4-hydroxy-6-(erythro-1,2, 3-trihydroxypropyl)dihydropteridine triphosphate from GTP and water; forms a homopolymer; GTP cyclohydrolase I 851651 folE 8111902 folE Streptococcus dysgalactiae subsp. equisimilis GGS_124 GTP cyclohydrolase I YP_002996574.1 851085 D 486410 CDS YP_002996575.1 251782273 8111903 851661..852467 1 NC_012891.1 similar to dihydropteroate synthase [Streptococcus pyogenes]; dihydropteroate synthase 852467 folP 8111903 folP Streptococcus dysgalactiae subsp. equisimilis GGS_124 dihydropteroate synthase YP_002996575.1 851661 D 486410 CDS YP_002996576.1 251782274 8111905 852475..852834 1 NC_012891.1 similar to dihydroneopterin aldolase [Streptococcus pyogenes MGAS5005]; dihydroneopterin aldolase 852834 folQ 8111905 folQ Streptococcus dysgalactiae subsp. equisimilis GGS_124 dihydroneopterin aldolase YP_002996576.1 852475 D 486410 CDS YP_002996577.1 251782275 8111906 852831..853331 1 NC_012891.1 similar to hydroxymethylpterin pyrophosphokinase [Streptococcus pyogenes]; hydroxymethylpterin pyrophosphokinase 853331 folK 8111906 folK Streptococcus dysgalactiae subsp. equisimilis GGS_124 hydroxymethylpterin pyrophosphokinase YP_002996577.1 852831 D 486410 CDS YP_002996578.1 251782276 8111904 853480..854367 1 NC_012891.1 catalyzes the reduction of UDP-N-acetylglucosamine enolpyruvate to form UDP-N-acetylmuramate in peptidoglycan biosynthesis; UDP-N-acetylenolpyruvoylglucosamine reductase 854367 murB 8111904 murB Streptococcus dysgalactiae subsp. equisimilis GGS_124 UDP-N-acetylenolpyruvoylglucosamine reductase YP_002996578.1 853480 D 486410 CDS YP_002996579.1 251782277 8111683 854416..855570 1 NC_012891.1 similar to PotA [Streptococcus pyogenes MGAS10394]; spermidine/putrescine transport ATP-binding protein 855570 potA 8111683 potA Streptococcus dysgalactiae subsp. equisimilis GGS_124 spermidine/putrescine transport ATP-binding protein YP_002996579.1 854416 D 486410 CDS YP_002996580.1 251782278 8111298 855533..856348 1 NC_012891.1 similar to PotB [Streptococcus pyogenes MGAS10394]; spermidine/putrescine transport system permease 856348 potB 8111298 potB Streptococcus dysgalactiae subsp. equisimilis GGS_124 spermidine/putrescine transport system permease YP_002996580.1 855533 D 486410 CDS YP_002996581.1 251782279 8111299 856345..857121 1 NC_012891.1 similar to spermidine/putrescine transport system permease protein [Streptococcus pyogenes MGAS5005]; spermidine/putrescine transport system permease 857121 potC 8111299 potC Streptococcus dysgalactiae subsp. equisimilis GGS_124 spermidine/putrescine transport system permease YP_002996581.1 856345 D 486410 CDS YP_002996582.1 251782280 8111300 857114..858187 1 NC_012891.1 similar to spermidine/putrescine extracellular binding protein [Streptococcus pyogenes str. Manfredo]; spermidine/putrescine extracellular binding protein 858187 potD 8111300 potD Streptococcus dysgalactiae subsp. equisimilis GGS_124 spermidine/putrescine extracellular binding protein YP_002996582.1 857114 D 486410 CDS YP_002996583.1 251782281 8111301 complement(858241..858906) 1 NC_012891.1 similar to two-component response regulator [Streptococcus pyogenes MGAS8232]; two-component response regulator 858906 dpiA 8111301 dpiA Streptococcus dysgalactiae subsp. equisimilis GGS_124 two-component response regulator YP_002996583.1 858241 R 486410 CDS YP_002996584.1 251782282 8111853 complement(858887..860131) 1 NC_012891.1 similar to sensor kinase dpiB [Streptococcus pyogenes MGAS10750]; two component system histidine kinase 860131 dpiB 8111853 dpiB Streptococcus dysgalactiae subsp. equisimilis GGS_124 two component system histidine kinase YP_002996584.1 858887 R 486410 CDS YP_002996585.1 251782283 8111854 860292..861623 1 NC_012891.1 similar to L-malate permease [Streptococcus pyogenes MGAS315]; L-malate permease 861623 malP 8111854 malP Streptococcus dysgalactiae subsp. equisimilis GGS_124 L-malate permease YP_002996585.1 860292 D 486410 CDS YP_002996586.1 251782284 8110923 861654..862820 1 NC_012891.1 similar to NAD-dependent malic enzyme [Streptococcus pyogenes NZ131]; NAD-dependent malic enzyme 862820 8110923 SDEG_0873 Streptococcus dysgalactiae subsp. equisimilis GGS_124 NAD-dependent malic enzyme YP_002996586.1 861654 D 486410 CDS YP_002996587.1 251782285 8110413 862952..864520 1 NC_012891.1 similar to chloride channel protein [Streptococcus pyogenes MGAS2096]; chloride channel protein 864520 8110413 SDEG_0874 Streptococcus dysgalactiae subsp. equisimilis GGS_124 chloride channel protein YP_002996587.1 862952 D 486410 CDS YP_002996588.1 251782286 8110414 complement(864579..865502) 1 NC_012891.1 similar to hypothetical protein STRINF 01402 [Streptococcus infantarius subsp. infantarius ATCC BAA-102]; hypothetical protein 865502 8110414 SDEG_0875 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996588.1 864579 R 486410 CDS YP_002996589.1 251782287 8110415 865722..866336 1 NC_012891.1 similar to lipase /acylhydrolase family protein [Streptococcus pyogenes MGAS5005]; lipase/acylhydrolase 866336 8110415 SDEG_0876 Streptococcus dysgalactiae subsp. equisimilis GGS_124 lipase/acylhydrolase YP_002996589.1 865722 D 486410 CDS YP_002996590.1 251782288 8110416 866513..867640 1 NC_012891.1 similar to hypothetical protein SPy 1117 [Streptococcus pyogenes M1 GAS]; hypothetical protein 867640 8110416 SDEG_0877 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996590.1 866513 D 486410 CDS YP_002996591.1 251782289 8110417 867688..868368 1 NC_012891.1 Involved in DNA double-strand break repair and recombination. Promotes the annealing of complementary single-stranded DNA and by simulation of RAD51 recombinase; DNA repair protein RadC 868368 radC 8110417 radC Streptococcus dysgalactiae subsp. equisimilis GGS_124 DNA repair protein RadC YP_002996591.1 867688 D 486410 CDS YP_002996592.1 251782290 8111349 complement(868370..869065) 1 NC_012891.1 similar to glutamine amidotransferase classI [Streptococcus pyogenes MGAS5005]; glutamine amidotransferase, classI 869065 8111349 SDEG_0879 Streptococcus dysgalactiae subsp. equisimilis GGS_124 glutamine amidotransferase, classI YP_002996592.1 868370 R 486410 CDS YP_002996593.1 251782291 8110418 complement(869074..869718) 1 NC_012891.1 modulates transcription in response to the NADH/NAD(+) redox state; redox-sensing transcriptional repressor Rex 869718 rex 8110418 rex Streptococcus dysgalactiae subsp. equisimilis GGS_124 redox-sensing transcriptional repressor Rex YP_002996593.1 869074 R 486410 CDS YP_002996594.1 251782292 8111042 complement(869896..870108) 1 NC_012891.1 similar to hypothetical protein stu1191 [Streptococcus thermophilus LMG 18311]; hypothetical protein 870108 8111042 SDEG_0881 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996594.1 869896 R 486410 CDS YP_002996595.1 251782293 8110419 complement(870176..870523) 1 NC_012891.1 similar to hypothetical protein Sez 1049 [Streptococcus equi subsp. zooepidemicus MGCS10565]; hypothetical protein 870523 8110419 SDEG_0882 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996595.1 870176 R 486410 CDS YP_002996596.1 251782294 8110420 complement(870513..871640) 1 NC_012891.1 similar to cysteine desulfhydrase [Streptococcus pyogenes MGAS5005]; cysteine desulfhydrase 871640 nifS2 8110420 nifS2 Streptococcus dysgalactiae subsp. equisimilis GGS_124 cysteine desulfhydrase YP_002996596.1 870513 R 486410 CDS YP_002996597.1 251782295 8111712 complement(871637..872617) 1 NC_012891.1 catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP; ribose-phosphate pyrophosphokinase 872617 8111712 SDEG_0884 Streptococcus dysgalactiae subsp. equisimilis GGS_124 ribose-phosphate pyrophosphokinase YP_002996597.1 871637 R 486410 CDS YP_002996598.1 251782296 8110421 complement(872746..873327) 1 NC_012891.1 similar to adenylate cyclase family [Streptococcus pyogenes MGAS10394]; adenylate cyclase family 873327 8110421 SDEG_0885 Streptococcus dysgalactiae subsp. equisimilis GGS_124 adenylate cyclase family YP_002996598.1 872746 R 486410 CDS YP_002996599.1 251782297 8110422 873421..874092 1 NC_012891.1 similar to GTP pyrophosphokinase [Streptococcus pyogenes MGAS5005]; GTP pyrophosphokinase 874092 8110422 SDEG_0886 Streptococcus dysgalactiae subsp. equisimilis GGS_124 GTP pyrophosphokinase YP_002996599.1 873421 D 486410 CDS YP_002996600.1 251782298 8110423 874064..874903 1 NC_012891.1 catalyzes the phosphorylation of NAD to NADP; inorganic polyphosphate/ATP-NAD kinase 874903 ppnK 8110423 ppnK Streptococcus dysgalactiae subsp. equisimilis GGS_124 inorganic polyphosphate/ATP-NAD kinase YP_002996600.1 874064 D 486410 CDS YP_002996601.1 251782299 8111303 874900..875805 1 NC_012891.1 similar to ribosomal large subunit pseudouridine synthase D [Streptococcus pyogenes MGAS10394]; ribosomal large subunit pseudouridine synthase D 875805 8111303 SDEG_0888 Streptococcus dysgalactiae subsp. equisimilis GGS_124 ribosomal large subunit pseudouridine synthase D YP_002996601.1 874900 D 486410 CDS YP_002996602.1 251782300 8110424 875809..876804 1 NC_012891.1 in Salmonella this enzyme is required for ethanolamine catabolism; has higher affinity for CoA than Pta; phosphotransacetylase 876804 eutD 8110424 eutD Streptococcus dysgalactiae subsp. equisimilis GGS_124 phosphotransacetylase YP_002996602.1 875809 D 486410 CDS YP_002996603.1 251782301 8111321 876913..877686 1 NC_012891.1 similar to short chain dehydrogenase [Streptococcus pyogenes MGAS10394]; short chain dehydrogenase 877686 8111321 SDEG_0890 Streptococcus dysgalactiae subsp. equisimilis GGS_124 short chain dehydrogenase YP_002996603.1 876913 D 486410 CDS YP_002996604.1 251782302 8110425 complement(877881..878570) 1 NC_012891.1 similar to Na+ driven multidrug efflux pump [Streptococcus pyogenes MGAS10270]; Na+ driven multidrug efflux pump 878570 8110425 SDEG_0891 Streptococcus dysgalactiae subsp. equisimilis GGS_124 Na+ driven multidrug efflux pump YP_002996604.1 877881 R 486410 CDS YP_002996605.1 251782303 8110426 878990..879718 1 NC_012891.1 similar to ABC transporter (ATP-binding protein) [Streptococcus pyogenes MGAS315]; ABC transporter 879718 8110426 SDEG_0892 Streptococcus dysgalactiae subsp. equisimilis GGS_124 ABC transporter YP_002996605.1 878990 D 486410 CDS YP_002996606.1 251782304 8110427 879711..881237 1 NC_012891.1 similar to glycine betaine transport system permease protein [Streptococcus pyogenes MGAS5005]; glycine betaine transport system permease 881237 8110427 SDEG_0893 Streptococcus dysgalactiae subsp. equisimilis GGS_124 glycine betaine transport system permease YP_002996606.1 879711 D 486410 CDS YP_002996607.1 251782305 8110428 881515..882498 1 NC_012891.1 similar to guanosine 5'-monophosphate oxidoreductase [Streptococcus pyogenes MGAS5005]; guanosine 5'-monophosphate oxidoreductase 882498 guaC 8110428 guaC Streptococcus dysgalactiae subsp. equisimilis GGS_124 guanosine 5'-monophosphate oxidoreductase YP_002996607.1 881515 D 486410 CDS YP_002996608.1 251782306 8112024 882803..883384 1 NC_012891.1 Catalyzes the transfer of the phosphoribosyl moiety from 5-phospho--D-ribosyl-1-pyrophosphate (PRib-PP) to the 6-oxo-guanine and -xanthine; xanthine phosphoribosyltransferase 883384 xpt 8112024 xpt Streptococcus dysgalactiae subsp. equisimilis GGS_124 xanthine phosphoribosyltransferase YP_002996608.1 882803 D 486410 CDS YP_002996609.1 251782307 8111953 883384..884658 1 NC_012891.1 similar to xanthine permease [Streptococcus pyogenes MGAS10270]; xanthine permease 884658 8111953 SDEG_0896 Streptococcus dysgalactiae subsp. equisimilis GGS_124 xanthine permease YP_002996609.1 883384 D 486410 CDS YP_002996610.1 251782308 8110429 complement(884787..885722) 1 NC_012891.1 similar to iron-sulfur cluster assembly /repair protein ApbE [Streptococcus pyogenes MGAS10270]; iron-sulfur cluster assembly/repair protein ApbE 885722 apbE 8110429 apbE Streptococcus dysgalactiae subsp. equisimilis GGS_124 iron-sulfur cluster assembly/repair protein ApbE YP_002996610.1 884787 R 486410 CDS YP_002996611.1 251782309 8112328 complement(885775..885960) 1 NC_012891.1 4-OT; member of subfamily 5; forms a dimer; the function in the Escherichia coli cell is unknown; 4-oxalocrotonate tautomerase 885960 8112328 SDEG_0898 Streptococcus dysgalactiae subsp. equisimilis GGS_124 4-oxalocrotonate tautomerase YP_002996611.1 885775 R 486410 CDS YP_002996612.1 251782310 8110430 886157..886759 1 NC_012891.1 similar to thymidine kinase Tdk [Streptococcus equi subsp. zooepidemicus MGCS10565]; thymidine kinase Tdk 886759 tdk 8110430 tdk Streptococcus dysgalactiae subsp. equisimilis GGS_124 thymidine kinase Tdk YP_002996612.1 886157 D 486410 CDS YP_002996613.1 251782311 8110514 886782..887861 1 NC_012891.1 recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2; peptide chain release factor 1 887861 prfA 8110514 prfA Streptococcus dysgalactiae subsp. equisimilis GGS_124 peptide chain release factor 1 YP_002996613.1 886782 D 486410 CDS YP_002996614.1 251782312 8111305 887861..888700 1 NC_012891.1 similar to peptide release factor-glutamine N5-methyltransferase [Streptococcus pyogenes MGAS5005]; peptide release factor-glutamine N5-methyltransferase 888700 hemK 8111305 hemK Streptococcus dysgalactiae subsp. equisimilis GGS_124 peptide release factor-glutamine N5-methyltransferase YP_002996614.1 887861 D 486410 CDS YP_002996615.1 251782313 8112028 888648..889274 1 NC_012891.1 similar to Sua5/YciO/YrdC/YwlC family protein [Streptococcus pyogenes MGAS10750]; Sua5/YciO/YrdC/YwlC family protein 889274 8112028 SDEG_0902 Streptococcus dysgalactiae subsp. equisimilis GGS_124 Sua5/YciO/YrdC/YwlC family protein YP_002996615.1 888648 D 486410 CDS YP_002996616.1 251782314 8110431 889285..889722 1 NC_012891.1 similar to COG0454, Histone acetyltransferase HPA2 and related acetyltransferases [Streptococcus pyogenes M49 591]; histone acetyltransferase HPA2-like protein 889722 8110431 SDEG_0903 Streptococcus dysgalactiae subsp. equisimilis GGS_124 histone acetyltransferase HPA2-like protein YP_002996616.1 889285 D 486410 CDS YP_002996617.1 251782315 8110432 889733..890989 1 NC_012891.1 catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate; serine hydroxymethyltransferase 890989 glyA 8110432 glyA Streptococcus dysgalactiae subsp. equisimilis GGS_124 serine hydroxymethyltransferase YP_002996617.1 889733 D 486410 CDS YP_002996618.1 251782316 8112012 890996..891973 1 NC_012891.1 similar to hypothetical protein M5005 Spy 0868 [Streptococcus pyogenes MGAS5005]; hypothetical protein 891973 8112012 SDEG_0905 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996618.1 890996 D 486410 CDS YP_002996619.1 251782317 8110433 891974..892576 1 NC_012891.1 similar to antigen [Streptococcus pyogenes MGAS5005]; hypothetical protein 892576 8110433 SDEG_0906 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996619.1 891974 D 486410 CDS YP_002996620.1 251782318 8110434 892586..894310 1 NC_012891.1 similar to multidrug resistance ABC transporter ATP-binding and permease protein [Streptococcus pyogenes MGAS10750]; multidrug resistance ABC transporter ATP-bindingprotein/permease 894310 8110434 SDEG_0907 Streptococcus dysgalactiae subsp. equisimilis GGS_124 multidrug resistance ABC transporter ATP-bindingprotein/permease YP_002996620.1 892586 D 486410 CDS YP_002996621.1 251782319 8110435 894307..896034 1 NC_012891.1 similar to ABC transporter ATP-binding membrane protein [Streptococcus pyogenes str. Manfredo]; ABC transporter ATP-binding protein 896034 8110435 SDEG_0908 Streptococcus dysgalactiae subsp. equisimilis GGS_124 ABC transporter ATP-binding protein YP_002996621.1 894307 D 486410 CDS YP_002996622.1 251782320 8110436 896274..897641 1 NC_012891.1 similar to NADH oxidase [Streptococcus pyogenes M1 GAS]; NADH oxidase 897641 nox 8110436 nox Streptococcus dysgalactiae subsp. equisimilis GGS_124 NADH oxidase YP_002996622.1 896274 D 486410 CDS YP_002996623.1 251782321 8111714 897710..898231 1 NC_012891.1 similar to dihydrofolate reductase [Streptococcus suis 98HAH33]; dihydrofolate reductase 898231 8111714 SDEG_0910 Streptococcus dysgalactiae subsp. equisimilis GGS_124 dihydrofolate reductase YP_002996623.1 897710 D 486410 CDS YP_002996624.1 251782322 8110437 complement(898300..899283) 1 NC_012891.1 Converts (S)-lactate and NAD(+) to pyruvate and NADH; L-lactate dehydrogenase 899283 ldh 8110437 ldh Streptococcus dysgalactiae subsp. equisimilis GGS_124 L-lactate dehydrogenase YP_002996624.1 898300 R 486410 CDS YP_002996625.1 251782323 8110890 899474..901978 1 NC_012891.1 negatively supercoils closed circular double-stranded DNA; DNA gyrase subunit A 901978 gyrA 8110890 gyrA Streptococcus dysgalactiae subsp. equisimilis GGS_124 DNA gyrase subunit A YP_002996625.1 899474 D 486410 CDS YP_002996626.1 251782324 8112025 901987..902736 1 NC_012891.1 similar to sortase [Streptococcus pyogenes NZ131]; sortase 902736 8112025 SDEG_0913 Streptococcus dysgalactiae subsp. equisimilis GGS_124 sortase YP_002996626.1 901987 D 486410 CDS YP_002996627.1 251782325 8110438 902819..903232 1 NC_012891.1 similar to lactoylglutathione lyase [Streptococcus pyogenes MGAS10394]; lactoylglutathione lyase 903232 8110438 SDEG_0914 Streptococcus dysgalactiae subsp. equisimilis GGS_124 lactoylglutathione lyase YP_002996627.1 902819 D 486410 CDS YP_002996628.1 251782326 8110439 903383..903559 1 NC_012891.1 probable ORF of N-terminal portion of the Lmb protein [Streptococcus dysgalactiae subsp. equisimilis] resulted from mutation by unknown reason; laminin-binding surface protein 903559 lmb 8110439 lmb Streptococcus dysgalactiae subsp. equisimilis GGS_124 laminin-binding surface protein YP_002996628.1 903383 D 486410 CDS YP_002996629.1 251782327 8110901 903564..903932 1 NC_012891.1 probable ORF of middlel portion of the Lmb protein [Streptococcus dysgalactiae subsp. equisimilis] resulted from mutation by unknown reason; laminin-binding surface protein 903932 lmb 8110901 lmb Streptococcus dysgalactiae subsp. equisimilis GGS_124 laminin-binding surface protein YP_002996629.1 903564 D 486410 CDS YP_002996630.1 251782328 8110902 903818..904318 1 NC_012891.1 probable ORF of C-terminal portion of the Lmb protein [Streptococcus dysgalactiae subsp. equisimilis] resulted from mutation by unknown reason; laminin-binding surface protein 904318 lmb 8110902 lmb Streptococcus dysgalactiae subsp. equisimilis GGS_124 laminin-binding surface protein YP_002996630.1 903818 D 486410 CDS YP_002996631.1 251782329 8110903 904315..904773 1 NC_012891.1 similar to histidine triad protein HtpA [Streptococcus equi subsp. zooepidemicus MGCS10565]; histidine triad protein 904773 htpA 8110903 htpA Streptococcus dysgalactiae subsp. equisimilis GGS_124 histidine triad protein YP_002996631.1 904315 D 486410 CDS YP_002996632.1 251782330 8112039 905046..906005 1 NC_012891.1 similar to extracellular protein [Streptococcus equi subsp. zooepidemicus MGCS10565]; extracellular protein 906005 8112039 SDEG_0919 Streptococcus dysgalactiae subsp. equisimilis GGS_124 extracellular protein YP_002996632.1 905046 D 486410 CDS YP_002996633.1 251782331 8110440 complement(906329..906478) 1 NC_012891.1 similar to transposase [Streptococcus pyogenes MGAS10750]; transposase 906478 8110440 SDEG_0920 Streptococcus dysgalactiae subsp. equisimilis GGS_124 transposase YP_002996633.1 906329 R 486410 CDS YP_002996634.1 251782332 8110441 complement(906471..907232) 1 NC_012891.1 similar to ISSdy1, transposase OrfB [Streptococcus agalactiae 2603V/R]; ISSdy1, transposase OrfB 907232 8110441 SDEG_0921 Streptococcus dysgalactiae subsp. equisimilis GGS_124 ISSdy1, transposase OrfB YP_002996634.1 906471 R 486410 CDS YP_002996635.1 251782333 8110442 complement(907286..907576) 1 NC_012891.1 similar to ISSag4, transposase OrfA [Streptococcus agalactiae A909]; ISSag4, transposase orfA 907576 8110442 SDEG_0922 Streptococcus dysgalactiae subsp. equisimilis GGS_124 ISSag4, transposase orfA YP_002996635.1 907286 R 486410 CDS YP_002996636.1 251782334 8110443 907849..908133 1 NC_012891.1 similar to hypothetical protein M6 Spy1729 [Streptococcus pyogenes MGAS10394]; hypothetical protein 908133 8110443 SDEG_0923 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996636.1 907849 D 486410 CDS YP_002996637.1 251782335 8110444 908548..909810 1 NC_012891.1 similar to periplasmic component of efflux system [Streptococcus pyogenes MGAS5005]; periplasmic protein of efflux system 909810 8110444 SDEG_0924 Streptococcus dysgalactiae subsp. equisimilis GGS_124 periplasmic protein of efflux system YP_002996637.1 908548 D 486410 CDS YP_002996638.1 251782336 8110445 909797..910471 1 NC_012891.1 similar to ABC transporter ATP-binding protein [Streptococcus pyogenes MGAS5005]; ABC transporter ATP-binding protein 910471 8110445 SDEG_0925 Streptococcus dysgalactiae subsp. equisimilis GGS_124 ABC transporter ATP-binding protein YP_002996638.1 909797 D 486410 CDS YP_002996639.1 251782337 8110446 910484..911701 1 NC_012891.1 similar to ABC transporter permease protein [Streptococcus pyogenes MGAS5005]; ABC transporter permease 911701 8110446 SDEG_0926 Streptococcus dysgalactiae subsp. equisimilis GGS_124 ABC transporter permease YP_002996639.1 910484 D 486410 CDS YP_002996640.1 251782338 8110447 911795..912448 1 NC_012891.1 similar to two-component response regulator [Streptococcus pyogenes MGAS5005]; two-component response regulator 912448 irr 8110447 irr Streptococcus dysgalactiae subsp. equisimilis GGS_124 two-component response regulator YP_002996640.1 911795 D 486410 CDS YP_002996641.1 251782339 8110871 912445..913833 1 NC_012891.1 similar to two component system histidine kinase [Streptococcus pyogenes MGAS5005]; two component system histidine kinase 913833 ihk 8110871 ihk Streptococcus dysgalactiae subsp. equisimilis GGS_124 two component system histidine kinase YP_002996641.1 912445 D 486410 CDS YP_002996642.1 251782340 8112049 913935..915563 1 NC_012891.1 similar to immunogenic secreted protein [Streptococcus pyogenes MGAS10270]; immunogenic secreted protein 915563 isp 8112049 isp Streptococcus dysgalactiae subsp. equisimilis GGS_124 immunogenic secreted protein YP_002996642.1 913935 D 486410 CDS YP_002996643.1 251782341 8110873 915641..915892 1 NC_012891.1 similar to hypothetical protein M28 Spy1706 [Streptococcus pyogenes MGAS6180]; hypothetical protein 915892 8110873 SDEG_0930 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996643.1 915641 D 486410 CDS YP_002996644.1 251782342 8110691 916224..916913 1 NC_012891.1 similar to hypothetical protein CdifQCD-6 20778 [Clostridium difficile QCD-63q42]; hypothetical protein 916913 8110691 SDEG_0931 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996644.1 916224 D 486410 CDS YP_002996645.1 251782343 8110692 917183..917860 1 NC_012891.1 similar to complement inhibitor protein [Streptococcus pyogenes MGAS2096]; complement inhibitor protein 917860 sic1-01 8110692 sic1-01 Streptococcus dysgalactiae subsp. equisimilis GGS_124 complement inhibitor protein YP_002996645.1 917183 D 486410 CDS YP_002996646.1 251782344 8110485 918282..921734 1 NC_012891.1 similar to streptococcal C5a peptidase [Streptococcus agalactiae NEM316]; streptococcal C5a peptidase 921734 scpB 8110485 scpB Streptococcus dysgalactiae subsp. equisimilis GGS_124 streptococcal C5a peptidase YP_002996646.1 918282 D 486410 CDS YP_002996647.1 251782345 8110468 921779..921895 1 NC_012891.1 similar to hypothetical protein MGAS9429 Spy1719 [Streptococcus pyogenes MGAS9429]; hypothetical protein 921895 8110468 SDEG_0934 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996647.1 921779 D 486410 CDS YP_002996648.1 251782346 8110693 921986..922906 1 NC_012891.1 similar to laminin binding protein [Streptococcus pyogenes MGAS5005]; laminin binding protein 922906 lmb 8110693 lmb Streptococcus dysgalactiae subsp. equisimilis GGS_124 laminin binding protein YP_002996648.1 921986 D 486410 CDS YP_002996649.1 251782347 8110904 922919..925387 1 NC_012891.1 similar to streptococcal histidine triad protein [Streptococcus pyogenes MGAS10394]; histidine triad protein 925387 8110904 SDEG_0936 Streptococcus dysgalactiae subsp. equisimilis GGS_124 histidine triad protein YP_002996649.1 922919 D 486410 CDS YP_002996650.1 251782348 8110694 complement(925455..925685) 1 NC_012891.1 similar to hypothetical protein [Streptococcus suis]; hypothetical protein 925685 8110694 SDEG_0937 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996650.1 925455 R 486410 CDS YP_002996651.1 251782349 8110695 925555..925755 1 NC_012891.1 similar to CsbD-like protein [Streptococcus pyogenes str. Manfredo]; CsbD-like protein 925755 8110695 SDEG_0938 Streptococcus dysgalactiae subsp. equisimilis GGS_124 CsbD-like protein YP_002996651.1 925555 D 486410 CDS YP_002996652.1 251782350 8110696 complement(925836..926462) 1 NC_012891.1 similar to dipeptide transport ATP-binding protein [Streptococcus pyogenes MGAS5005]; dipeptide transport ATP-binding protein 926462 dppE 8110696 dppE Streptococcus dysgalactiae subsp. equisimilis GGS_124 dipeptide transport ATP-binding protein YP_002996652.1 925836 R 486410 CDS YP_002996653.1 251782351 8111860 complement(926446..927249) 1 NC_012891.1 similar to dipeptide transport ATP-binding protein [Streptococcus pyogenes MGAS5005]; dipeptide transport ATP-binding protein 927249 dppD 8111860 dppD Streptococcus dysgalactiae subsp. equisimilis GGS_124 dipeptide transport ATP-binding protein YP_002996653.1 926446 R 486410 CDS YP_002996654.1 251782352 8111859 complement(927261..928082) 1 NC_012891.1 similar to dipeptide transport system permease protein [Streptococcus pyogenes MGAS5005]; dipeptide transport system permease 928082 dppC 8111859 dppC Streptococcus dysgalactiae subsp. equisimilis GGS_124 dipeptide transport system permease YP_002996654.1 927261 R 486410 CDS YP_002996655.1 251782353 8111858 complement(928079..929056) 1 NC_012891.1 similar to dipeptide transport system permease protein [Streptococcus pyogenes MGAS5005]; dipeptide transport system permease 929056 dppB 8111858 dppB Streptococcus dysgalactiae subsp. equisimilis GGS_124 dipeptide transport system permease YP_002996655.1 928079 R 486410 CDS YP_002996656.1 251782354 8111857 complement(929169..930224) 1 NC_012891.1 similar to dipeptide-binding protein [Streptococcus pyogenes MGAS5005]; dipeptide-binding protein 930224 dppA 8111857 dppA Streptococcus dysgalactiae subsp. equisimilis GGS_124 dipeptide-binding protein YP_002996656.1 929169 R 486410 CDS YP_002996657.1 251782355 8111855 complement(930218..930802) 1 NC_012891.1 similar to dipeptide-binding protein [Streptococcus pyogenes MGAS10394]; dipeptide-binding protein 930802 dppA 8111855 dppA Streptococcus dysgalactiae subsp. equisimilis GGS_124 dipeptide-binding protein YP_002996657.1 930218 R 486410 CDS YP_002996658.1 251782356 8111856 931273..931398 1 NC_012891.1 similar to transposase [Streptococcus pyogenes MGAS10394]; transposase 931398 8111856 SDEG_0945 Streptococcus dysgalactiae subsp. equisimilis GGS_124 transposase YP_002996658.1 931273 D 486410 CDS YP_002996659.1 251782357 8110697 931426..932295 1 NC_012891.1 similar to transposase [Streptococcus pyogenes MGAS10394]; transposase 932295 8110697 SDEG_0946 Streptococcus dysgalactiae subsp. equisimilis GGS_124 transposase YP_002996659.1 931426 D 486410 CDS YP_002996660.1 251782358 8110698 932410..933633 1 NC_012891.1 similar to UDP-N-acetylmuramoylpentapeptide-lysine N(6)-alanyltransferase / UDP-N-acetylmuramoylpentapeptide-lysine N(6)-seryltransferase [Streptococcus pyogenes MGAS10750]; UDP-N-acetylmuramoylpentapeptide-lysineN(6)- alanyltransferase/UDP-N-acetylmuramoylpentapeptide- lysineN(6)-seryltransferase 933633 8110698 SDEG_0947 Streptococcus dysgalactiae subsp. equisimilis GGS_124 UDP-N-acetylmuramoylpentapeptide-lysineN(6)- alanyltransferase/UDP-N-acetylmuramoylpentapeptide- lysineN(6)-seryltransferase YP_002996660.1 932410 D 486410 CDS YP_002996661.1 251782359 8110699 complement(933734..934942) 1 NC_012891.1 similar to Na+/H+ antiporter [Streptococcus agalactiae A909]; Na+/H+ antiporter 934942 8110699 SDEG_0948 Streptococcus dysgalactiae subsp. equisimilis GGS_124 Na+/H+ antiporter YP_002996661.1 933734 R 486410 CDS YP_002996662.1 251782360 8110700 935209..936186 1 NC_012891.1 similar to IS1562 transposase [Streptococcus pyogenes MGAS8232]; IS1562 transposase 936186 tra 8110700 tra Streptococcus dysgalactiae subsp. equisimilis GGS_124 IS1562 transposase YP_002996662.1 935209 D 486410 CDS YP_002996663.1 251782361 8111922 936190..936291 1 NC_012891.1 similar to transposase [Streptococcus pyogenes MGAS10750]; transposase 936291 8111922 SDEG_0950 Streptococcus dysgalactiae subsp. equisimilis GGS_124 transposase YP_002996663.1 936190 D 486410 CDS YP_002996664.1 251782362 8110701 936236..936652 1 NC_012891.1 similar to transposase [Streptococcus pyogenes MGAS10750]; transposase 936652 8110701 SDEG_0951 Streptococcus dysgalactiae subsp. equisimilis GGS_124 transposase YP_002996664.1 936236 D 486410 CDS YP_002996665.1 251782363 8110702 936951..937166 1 NC_012891.1 similar to hypothetical protein CKL 3238 [Clostridium kluyveri DSM 555]; hypothetical protein 937166 8110702 SDEG_0952 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996665.1 936951 D 486410 CDS YP_002996666.1 251782364 8110703 937163..938005 1 NC_012891.1 similar to Type II restriction enzyme EcoRI [Parabacteroides distasonis ATCC 8503]; type II restriction enzyme EcoRI 938005 8110703 SDEG_0953 Streptococcus dysgalactiae subsp. equisimilis GGS_124 type II restriction enzyme EcoRI YP_002996666.1 937163 D 486410 CDS YP_002996667.1 251782365 8110704 938012..938995 1 NC_012891.1 similar to type II restriction enzyme EcoRI-like protein [Microcystis aeruginosa NIES-843]; type II restriction enzyme EcoRI-like protein 938995 8110704 SDEG_0954 Streptococcus dysgalactiae subsp. equisimilis GGS_124 type II restriction enzyme EcoRI-like protein YP_002996667.1 938012 D 486410 CDS YP_002996668.1 251782366 8110705 complement(939004..940458) 1 NC_012891.1 similar to transposase [Streptococcus pyogenes MGAS10394]; transposase 940458 8110705 SDEG_0955 Streptococcus dysgalactiae subsp. equisimilis GGS_124 transposase YP_002996668.1 939004 R 486410 CDS YP_002996669.1 251782367 8110706 complement(940593..942155) 1 NC_012891.1 contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway; GMP synthase 942155 guaA 8110706 guaA Streptococcus dysgalactiae subsp. equisimilis GGS_124 GMP synthase YP_002996669.1 940593 R 486410 CDS YP_002996670.1 251782368 8112022 942322..943764 1 NC_012891.1 similar to hypothetical protein SpyM50880 [Streptococcus pyogenes str. Manfredo]; hypothetical protein 943764 8112022 SDEG_0957 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996670.1 942322 D 486410 CDS YP_002996671.1 251782369 8110707 943844..944542 1 NC_012891.1 similar to GntR family transcriptional regulator [Streptococcus pyogenes M1GAS]; GntR family transcriptional regulator 944542 8110707 SDEG_0958 Streptococcus dysgalactiae subsp. equisimilis GGS_124 GntR family transcriptional regulator YP_002996671.1 943844 D 486410 CDS YP_002996672.1 251782370 8110708 944643..944984 1 NC_012891.1 similar to signal recognition particle associated protein [Streptococcus pyogenes MGAS10750]; DNA-binding protein 944984 ylxM 8110708 ylxM Streptococcus dysgalactiae subsp. equisimilis GGS_124 DNA-binding protein YP_002996672.1 944643 D 486410 CDS YP_002996673.1 251782371 8111967 944993..946561 1 NC_012891.1 similar to signal recognition particle subunit FFH/SRP54 [Streptococcus pyogenes MGAS10270]; signal recognition particle subunit 946561 ffh 8111967 ffh Streptococcus dysgalactiae subsp. equisimilis GGS_124 signal recognition particle subunit YP_002996673.1 944993 D 486410 CDS YP_002996674.1 251782372 8111889 946993..947574 1 NC_012891.1 similar to ferric reductase [Oenococcus oeni PSU-1]; ferric reductase 947574 8111889 SDEG_0961 Streptococcus dysgalactiae subsp. equisimilis GGS_124 ferric reductase YP_002996674.1 946993 D 486410 CDS YP_002996675.1 251782373 8110709 947647..948048 1 NC_012891.1 similar to predicted ferric reductase [Bifidobacterium animalis subsp. lactis HN019]; ferric reductase 948048 8110709 SDEG_0962 Streptococcus dysgalactiae subsp. equisimilis GGS_124 ferric reductase YP_002996675.1 947647 D 486410 CDS YP_002996676.1 251782374 8110710 complement(948195..948887) 1 NC_012891.1 similar to phage transcriptional repressor [Streptococcus equi subsp.z ooepidemicus MGCS10565]; phage transcriptional repressor 948887 8110710 SDEG_0963 Streptococcus dysgalactiae subsp. equisimilis GGS_124 phage transcriptional repressor YP_002996676.1 948195 R 486410 CDS YP_002996677.1 251782375 8110711 949062..950087 1 NC_012891.1 similar to oxidoreductase [Lactobacillus plantarum WCFS1]; oxidoreductase 950087 8110711 SDEG_0964 Streptococcus dysgalactiae subsp. equisimilis GGS_124 oxidoreductase YP_002996677.1 949062 D 486410 CDS YP_002996678.1 251782376 8110712 950227..950775 1 NC_012891.1 similar to DNA-binding response regulator [Streptococcus agalactiae 2603V/R]; DNA-binding response regulator 950775 8110712 SDEG_0965 Streptococcus dysgalactiae subsp. equisimilis GGS_124 DNA-binding response regulator YP_002996678.1 950227 D 486410 CDS YP_002996679.1 251782377 8110713 950759..951829 1 NC_012891.1 similar to sensor histidine kinase [Streptococcus agalactiae 2603V/R]; sensor histidine kinase 951829 8110713 SDEG_0966 Streptococcus dysgalactiae subsp. equisimilis GGS_124 sensor histidine kinase YP_002996679.1 950759 D 486410 CDS YP_002996680.1 251782378 8110714 951954..952376 1 NC_012891.1 similar to hypothetical protein CAT7 10785 [Carnobacterium sp. AT7]; hypothetical protein 952376 8110714 SDEG_0967 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996680.1 951954 D 486410 CDS YP_002996681.1 251782379 8110715 complement(952407..952958) 1 NC_012891.1 similar to peptido glycan branched peptide synthesis protein, alanine adding enzyme [Streptococcust hermophilus CNRZ1066]; peptido glycan branched peptide synthesis protein, alanine adding enzyme 952958 murO 8110715 murO Streptococcus dysgalactiae subsp. equisimilis GGS_124 peptido glycan branched peptide synthesis protein, alanine adding enzyme YP_002996681.1 952407 R 486410 CDS YP_002996682.1 251782380 8111690 complement(952967..953386) 1 NC_012891.1 similar to peptido glycan branched peptide synthesis protein, alanine adding enzyme [Streptococcus thermophilus CNRZ1066]; peptido glycan branched peptide synthesis protein, alanine adding enzyme 953386 murO 8111690 murO Streptococcus dysgalactiae subsp. equisimilis GGS_124 peptido glycan branched peptide synthesis protein, alanine adding enzyme YP_002996682.1 952967 R 486410 CDS YP_002996683.1 251782381 8111691 954030..955100 1 NC_012891.1 site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; cell division protein FtsK may regulate the XerS; site-specific tyrosine recombinase XerS 955100 xerS 8111691 xerS Streptococcus dysgalactiae subsp. equisimilis GGS_124 site-specific tyrosine recombinase XerS YP_002996683.1 954030 D 486410 CDS YP_002996684.1 251782382 8111952 955177..955617 1 NC_012891.1 similar to hypothetical protein SSU98 1762 [Streptococcus suis 98HAH33]; hypothetical protein 955617 8111952 SDEG_0971 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996684.1 955177 D 486410 CDS YP_002996685.1 251782383 8110716 complement(955688..956638) 1 NC_012891.1 similar to 14-dihydroxy-2-naphthoate octaprenyl transferase [Streptococcus suis 05ZYH33]; 1,4-dihydroxy-2-naphthoate octaprenyltransferase 956638 8110716 SDEG_0972 Streptococcus dysgalactiae subsp. equisimilis GGS_124 1,4-dihydroxy-2-naphthoate octaprenyltransferase YP_002996685.1 955688 R 486410 CDS YP_002996686.1 251782384 8110717 complement(956628..956957) 1 NC_012891.1 similar to membrane -associated lipoprotein involved in thiamine biosynthesis [Streptococcus suis 98HAH33]; thiamine biosynthesis lipoprotein 956957 8110717 SDEG_0973 Streptococcus dysgalactiae subsp. equisimilis GGS_124 thiamine biosynthesis lipoprotein YP_002996686.1 956628 R 486410 CDS YP_002996687.1 251782385 8110718 956950..957438 1 NC_012891.1 similar to hypothetical protein SSU05 1758 [Streptococcus suis 05ZYH33]; hypothetical protein 957438 8110718 SDEG_0974 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996687.1 956950 D 486410 CDS YP_002996688.1 251782386 8110719 complement(957497..958444) 1 NC_012891.1 similar to TCS senso kinase BceS [Streptococcus equi subsp. zooepidemicus MGCS10565]; two component system histidine kinase 958444 bceS 8110719 bceS Streptococcus dysgalactiae subsp. equisimilis GGS_124 two component system histidine kinase YP_002996688.1 957497 R 486410 CDS YP_002996689.1 251782387 8112369 complement(958441..959106) 1 NC_012891.1 similar to TCS response regulator BceR [Streptococcus equi subsp. zooepidemicus MGCS10565]; two-component response regulator 959106 bceR 8112369 bceR Streptococcus dysgalactiae subsp. equisimilis GGS_124 two-component response regulator YP_002996689.1 958441 R 486410 CDS YP_002996690.1 251782388 8112368 complement(959150..961105) 1 NC_012891.1 similar to bacitracin export permease protein BceB [Streptococcus equi subsp. zooepidemicus MGCS10565]; bacitracin export permease 961105 bceB 8112368 bceB Streptococcus dysgalactiae subsp. equisimilis GGS_124 bacitracin export permease YP_002996690.1 959150 R 486410 CDS YP_002996691.1 251782389 8112367 complement(961107..961859) 1 NC_012891.1 similar to ABC transporter ATP-binding protein [Streptococcus equi subsp. zooepidemicus MGCS10565]; ABC transporter ATP-binding protein 961859 8112367 SDEG_0978 Streptococcus dysgalactiae subsp. equisimilis GGS_124 ABC transporter ATP-binding protein YP_002996691.1 961107 R 486410 CDS YP_002996692.1 251782390 8110720 complement(961896..962861) 1 NC_012891.1 similar to nisin-resistanceprotein, [Streptococcus agalactiae 2603V/R]; nisin-resistanceprotein 962861 8110720 SDEG_0979 Streptococcus dysgalactiae subsp. equisimilis GGS_124 nisin-resistanceprotein YP_002996692.1 961896 R 486410 CDS YP_002996693.1 251782391 8110721 963027..963509 1 NC_012891.1 similar to hypothetical protein MGAS10750 Spy1061 [Streptococcus pyogenes MGAS10750]; hypothetical protein 963509 8110721 SDEG_0980 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996693.1 963027 D 486410 CDS YP_002996694.1 251782392 8110722 963776..964828 1 NC_012891.1 similar to (citrate [pro-3S]-lyase)-ligase [Streptococcus pyogenes MGAS5005]; (citrate [pro-3S]-lyase)-ligase 964828 citC 8110722 citC Streptococcus dysgalactiae subsp. equisimilis GGS_124 (citrate [pro-3S]-lyase)-ligase YP_002996694.1 963776 D 486410 CDS YP_002996695.1 251782393 8111615 complement(964964..966358) 1 NC_012891.1 Converts oxaloacetate to phosphoenolpyruvate using ATP as an energy source; oxaloacetate decarboxylase 966358 oadA1 8111615 oadA1 Streptococcus dysgalactiae subsp. equisimilis GGS_124 oxaloacetate decarboxylase YP_002996695.1 964964 R 486410 CDS YP_002996696.1 251782394 8111728 966662..967891 1 NC_012891.1 similar to transposase [Streptococcus pneumoniae SP9-BS68]; transposase 967891 8111728 SDEG_0983 Streptococcus dysgalactiae subsp. equisimilis GGS_124 transposase YP_002996696.1 966662 D 486410 CDS YP_002996697.1 251782395 8110723 complement(967991..968665) 1 NC_012891.1 2'-(5''-phosphoribosyl)-3'-dephospho-CoA transferase; holo-citrate lyase synthase; CitG forms the prosthetic group precursor 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA which is then transferred to apo-ACP by CitX to produce holo-ACP and pyrophosphate; 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase 968665 citX 8110723 citX Streptococcus dysgalactiae subsp. equisimilis GGS_124 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase YP_002996697.1 967991 R 486410 CDS YP_002996698.1 251782396 8111620 complement(968562..970094) 1 NC_012891.1 similar to citrate CoA-transferase [Streptococcus pyogenes MGAS10394]; citrate CoA-transferase 970094 citF 8111620 citF Streptococcus dysgalactiae subsp. equisimilis GGS_124 citrate CoA-transferase YP_002996698.1 968562 R 486410 CDS YP_002996699.1 251782397 8111618 complement(970097..970984) 1 NC_012891.1 similar to citrate lyase beta chain [Streptococcus pyogenes MGAS10394]; citrate lyase subunit beta 970984 citE 8111618 citE Streptococcus dysgalactiae subsp. equisimilis GGS_124 citrate lyase subunit beta YP_002996699.1 970097 R 486410 CDS YP_002996700.1 251782398 8111617 complement(970972..971280) 1 NC_012891.1 acyl carrier protein; with CitE and CitF catalyzes the formation of oxaloacetate from citrate; citrate lyase subunit gamma 971280 citD 8111617 citD Streptococcus dysgalactiae subsp. equisimilis GGS_124 citrate lyase subunit gamma YP_002996700.1 970972 R 486410 CDS YP_002996701.1 251782399 8111616 complement(971316..971450) 1 NC_012891.1 similar to hypothetical protein M5005 Spy 0904 [Streptococcus pyogenes MGAS5005]; hypothetical protein 971450 8111616 SDEG_0988 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996701.1 971316 R 486410 CDS YP_002996702.1 251782400 8110724 complement(971468..972589) 1 NC_012891.1 similar to oxaloacetate decarboxylase beta chain [Streptococcus pyogenes MGAS5005]; oxaloacetate decarboxylase subunit beta 972589 oadB 8110724 oadB Streptococcus dysgalactiae subsp. equisimilis GGS_124 oxaloacetate decarboxylase subunit beta YP_002996702.1 971468 R 486410 CDS YP_002996703.1 251782401 8111730 complement(972634..973029) 1 NC_012891.1 composes the biotin carboxyl carrier protein subunit of the acetyl-CoA carboxylase complex, the enzyme that catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, which in turn controls the rate of fatty acid metabolism; acetyl-CoA carboxylase biotin carboxyl carrier protein subunit 973029 8111730 SDEG_0990 Streptococcus dysgalactiae subsp. equisimilis GGS_124 acetyl-CoA carboxylase biotin carboxyl carrier protein subunit YP_002996703.1 972634 R 486410 CDS YP_002996704.1 251782402 8110725 complement(973091..973414) 1 NC_012891.1 similar to hypothetical protein MGAS10750 Spy1050 [Streptococcus pyogenes MGAS10750]; hypothetical protein 973414 8110725 SDEG_0991 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996704.1 973091 R 486410 CDS YP_002996705.1 251782403 8110726 973795..975198 1 NC_012891.1 similar to Mg2+/citrate complex secondary transporter [Streptococcus pyogenes MGAS5005]; Mg2+/citrate complex secondary transporter 975198 8110726 SDEG_0992 Streptococcus dysgalactiae subsp. equisimilis GGS_124 Mg2+/citrate complex secondary transporter YP_002996705.1 973795 D 486410 CDS YP_002996706.1 251782404 8110727 975356..976051 1 NC_012891.1 similar to GntR family transcriptional regulator [Streptococcus pyogenes MGAS5005]; GntR family transcriptional regulator 976051 citG 8110727 citG Streptococcus dysgalactiae subsp. equisimilis GGS_124 GntR family transcriptional regulator YP_002996706.1 975356 D 486410 CDS YP_002996707.1 251782405 8111619 976044..976928 1 NC_012891.1 similar to 2-(5''-triphosphoribosyl)-3'- dephosphocoenzyme-A synthase [Streptococcus pyogenes MGAS5005]; 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase 976928 8111619 SDEG_0994 Streptococcus dysgalactiae subsp. equisimilis GGS_124 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase YP_002996707.1 976044 D 486410 CDS YP_002996708.1 251782406 8110728 complement(977049..978113) 1 NC_012891.1 similar to ammonia monooxygenase [Streptococcus equi subsp. zooepidemicus MGCS10565]; ammonia monooxygenase 978113 8110728 SDEG_0995 Streptococcus dysgalactiae subsp. equisimilis GGS_124 ammonia monooxygenase YP_002996708.1 977049 R 486410 CDS YP_002996709.1 251782407 8110729 complement(978295..979425) 1 NC_012891.1 similar to oxaloacetate decarboxylase beta chain [Streptococcus pyogenes MGAS10394]; oxaloacetate decarboxylase subunit beta 979425 8110729 SDEG_0996 Streptococcus dysgalactiae subsp. equisimilis GGS_124 oxaloacetate decarboxylase subunit beta YP_002996709.1 978295 R 486410 CDS YP_002996710.1 251782408 8110730 complement(979435..979785) 1 NC_012891.1 similar to methylmalonyl-CoA decarboxylase gamma-subunit [Streptococcus pyogenes MGAS315]; methylmalonyl-CoA decarboxylase gamma-subunit 979785 8110730 SDEG_0997 Streptococcus dysgalactiae subsp. equisimilis GGS_124 methylmalonyl-CoA decarboxylase gamma-subunit YP_002996710.1 979435 R 486410 CDS YP_002996711.1 251782409 8110731 complement(979785..980099) 1 NC_012891.1 similar to hypothetical membrane associated protein [Streptococcus pyogenes MGAS10394]; hypothetical protein 980099 8110731 SDEG_0998 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996711.1 979785 R 486410 CDS YP_002996712.1 251782410 8110732 complement(980142..981524) 1 NC_012891.1 Converts oxaloacetate to phosphoenolpyruvate using ATP as an energy source; oxaloacetate decarboxylase 981524 oadA2 8110732 oadA2 Streptococcus dysgalactiae subsp. equisimilis GGS_124 oxaloacetate decarboxylase YP_002996712.1 980142 R 486410 CDS YP_002996713.1 251782411 8111729 complement(981701..983095) 1 NC_012891.1 TrmFO; Gid; glucose-inhibited division protein; similar to GidA; the gene from Bacillus subtilis encodes a tRNA-methyltransferase that utilizes folate as the carbon donor and bound flavin as reductant; modifies tRNA at position 54 (uridine) of the T-psi loop to form a C5-methyluridine; tRNA (uracil-5-)-methyltransferase Gid 983095 gid 8111729 gid Streptococcus dysgalactiae subsp. equisimilis GGS_124 tRNA (uracil-5-)-methyltransferase Gid YP_002996713.1 981701 R 486410 CDS YP_002996714.1 251782412 8111991 complement(983198..983914) 1 NC_012891.1 similar to hypothetical protein MGAS10270 Spy1006 [Streptococcus pyogenes MGAS10270]; hypothetical protein 983914 satE 8111991 satE Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996714.1 983198 R 486410 CDS YP_002996715.1 251782413 8110463 complement(983907..984572) 1 NC_012891.1 similar to hypothetical protein MGAS10270 Spy1005 [Streptococcus pyogenes MGAS10270]; hypothetical protein 984572 satD 8110463 satD Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996715.1 983907 R 486410 CDS YP_002996716.1 251782414 8110462 complement(984679..985665) 1 NC_012891.1 catalyzes the formation of pyruvate from lactate; D-lactate dehydrogenase 985665 ddh 8110462 ddh Streptococcus dysgalactiae subsp. equisimilis GGS_124 D-lactate dehydrogenase YP_002996716.1 984679 R 486410 CDS YP_002996717.1 251782415 8111662 complement(985809..986705) 1 NC_012891.1 similar to hypothetical protein SAK 0820 [Streptococcus agalactiae A909]; hypothetical protein 986705 8111662 SDEG_1004 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996717.1 985809 R 486410 CDS YP_002996718.1 251782416 8110733 986893..987837 1 NC_012891.1 similar to transposase [Streptococcus pyogenes MGAS2096]; transposase 987837 8110733 SDEG_1005 Streptococcus dysgalactiae subsp. equisimilis GGS_124 transposase YP_002996718.1 986893 D 486410 CDS YP_002996719.1 251782417 8110734 987860..988021 1 NC_012891.1 similar to transcriptional regulator, LysR family [Streptococcus agalactiae H36B]; LysR family transcriptional regulator 988021 8110734 SDEG_1006 Streptococcus dysgalactiae subsp. equisimilis GGS_124 LysR family transcriptional regulator YP_002996719.1 987860 D 486410 CDS YP_002996720.1 251782418 8110735 988132..988743 1 NC_012891.1 similar to hypothetical protein gbs0666 [Streptococcus agalactiae NEM316]; hypothetical protein 988743 8110735 SDEG_1007 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996720.1 988132 D 486410 CDS YP_002996721.1 251782419 8110736 complement(988819..990951) 1 NC_012891.1 catalyzes the ATP-dependent breakage of single-stranded DNA followed by passage and rejoining, maintains net negative superhelicity; DNA topoisomerase I 990951 8110736 SDEG_1008 Streptococcus dysgalactiae subsp. equisimilis GGS_124 DNA topoisomerase I YP_002996721.1 988819 R 486410 CDS YP_002996722.1 251782420 8110737 complement(991052..991894) 1 NC_012891.1 similar to DNA processing protein [Streptococcus pyogenes MGAS10750]; DNA processing protein 991894 smf 8110737 smf Streptococcus dysgalactiae subsp. equisimilis GGS_124 DNA processing protein YP_002996722.1 991052 R 486410 CDS YP_002996723.1 251782421 8110491 complement(992001..992771) 1 NC_012891.1 RNH2; RNase HII; binds manganese; endonuclease which specifically degrades the RNA of RNA-DNA hybrids; ribonuclease HII 992771 rnhB 8110491 rnhB Streptococcus dysgalactiae subsp. equisimilis GGS_124 ribonuclease HII YP_002996723.1 992001 R 486410 CDS YP_002996724.1 251782422 8111051 complement(992761..993609) 1 NC_012891.1 essential GTPase; functions in ribosome assembly; binds a unique part of the 23S rRNA; interacts with ribosomal protein L25(Ctc); ribosomal biogenesis GTPase 993609 rbgA 8111051 rbgA Streptococcus dysgalactiae subsp. equisimilis GGS_124 ribosomal biogenesis GTPase YP_002996724.1 992761 R 486410 CDS YP_002996725.1 251782423 8110738 complement(994332..994562) 1 NC_012891.1 similar to hypothetical protein SPCG 0150 [Streptococcus pneumoniae CGSP14]; hypothetical protein 994562 8110738 SDEG_1012 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996725.1 994332 R 486410 CDS YP_002996726.1 251782424 8110739 complement(994781..995668) 1 NC_012891.1 similar to XRE family transcriptional regulator [Streptococcus thermophilus LMD-9]; XRE family transcriptional regulator 995668 8110739 SDEG_1013 Streptococcus dysgalactiae subsp. equisimilis GGS_124 XRE family transcriptional regulator YP_002996726.1 994781 R 486410 CDS YP_002996727.1 251782425 8110740 996008..996448 1 NC_012891.1 similar to hypothetical cytosolic protein [Streptococcus pyogenes MGAS10750]; hypothetical protein 996448 8110740 SDEG_1014 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996727.1 996008 D 486410 CDS YP_002996728.1 251782426 8110741 996445..997095 1 NC_012891.1 similar to hypothetical protein M5005 Spy 0880 [Streptococcus pyogenes MGAS5005]; hypothetical protein 997095 8110741 SDEG_1015 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996728.1 996445 D 486410 CDS YP_002996729.1 251782427 8110742 997213..998124 1 NC_012891.1 similar to diacylglycerol kinase family protein [Streptococcus pyogenes MGAS2096]; diacylglycerol kinase 998124 8110742 SDEG_1016 Streptococcus dysgalactiae subsp. equisimilis GGS_124 diacylglycerol kinase YP_002996729.1 997213 D 486410 CDS YP_002996730.1 251782428 8110743 complement(998164..998613) 1 NC_012891.1 similar to hypothetical protein M28 Spy0852 [Streptococcus pyogenes MGAS6180]; hypothetical protein 998613 8110743 SDEG_1017 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996730.1 998164 R 486410 CDS YP_002996731.1 251782429 8110744 complement(998750..998956) 1 NC_012891.1 similar to hypothetical protein MGAS2096 Spy1031 [Streptococcus pyogenes MGAS2096]; hypothetical protein 998956 8110744 SDEG_1018 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996731.1 998750 R 486410 CDS YP_002996732.1 251782430 8110745 complement(999285..1000880) 1 NC_012891.1 similar to ABC transporter ATP-binding protein [Streptococcus pyogenes MGAS6180]; ABC transporter ATP-binding protein 1000880 8110745 SDEG_1019 Streptococcus dysgalactiae subsp. equisimilis GGS_124 ABC transporter ATP-binding protein YP_002996732.1 999285 R 486410 CDS YP_002996733.1 251782431 8110746 complement(1000932..1002050) 1 NC_012891.1 plasminogen activator; similar to streptokinase precursor [Streptococcus dysgalactiae subsp. equisimilis]; streptokinase 1002050 skc 8110746 skc Streptococcus dysgalactiae subsp. equisimilis GGS_124 streptokinase YP_002996733.1 1000932 R 486410 CDS YP_002996734.1 251782432 8110488 complement(1002400..1002960) 1 NC_012891.1 similar to hypothetical protein spyM18 1159 [Streptococcus pyogenes MGAS8232]; hypothetical protein 1002960 8110488 SDEG_1021 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996734.1 1002400 R 486410 CDS YP_002996735.1 251782433 8110747 complement(1002957..1003793) 1 NC_012891.1 catalyzes the formation of pyridoxal 5'-phosphate from pyridoxal; pyridoxamine kinase 1003793 pdxK 8110747 pdxK Streptococcus dysgalactiae subsp. equisimilis GGS_124 pyridoxamine kinase YP_002996735.1 1002957 R 486410 CDS YP_002996736.1 251782434 8111757 1003895..1005160 1 NC_012891.1 similar to transcriptional regulator; transcriptional regulator 1005160 8111757 SDEG_1023 Streptococcus dysgalactiae subsp. equisimilis GGS_124 transcriptional regulator YP_002996736.1 1003895 D 486410 CDS YP_002996737.1 251782435 8110748 complement(1005221..1005577) 1 NC_012891.1 similar to hypothetical protein SPs1051 [Streptococcus pyogenes SSI-1]; hypothetical protein 1005577 8110748 SDEG_1024 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996737.1 1005221 R 486410 CDS YP_002996738.1 251782436 8110749 complement(1005700..1006776) 1 NC_012891.1 catalyzes the formation of 4-aspartyl phosphate from aspartate 4-semialdehyde; aspartate-semialdehyde dehydrogenase 1006776 asd 8110749 asd Streptococcus dysgalactiae subsp. equisimilis GGS_124 aspartate-semialdehyde dehydrogenase YP_002996738.1 1005700 R 486410 CDS YP_002996739.1 251782437 8112347 complement(1007064..1008641) 1 NC_012891.1 similar to cardiolipin synthetase [Streptococcus pyogenes MGAS10394]; cardiolipin synthetase 1008641 8112347 SDEG_1026 Streptococcus dysgalactiae subsp. equisimilis GGS_124 cardiolipin synthetase YP_002996739.1 1007064 R 486410 CDS YP_002996740.1 251782438 8110750 complement(1009011..1009970) 1 NC_012891.1 similar to C5a peptidase precursor ScpZ [Streptococcus equi subsp. zooepidemicusMGCS10565]; C5a peptidase 1009970 scp 8110750 scp Streptococcus dysgalactiae subsp. equisimilis GGS_124 C5a peptidase YP_002996740.1 1009011 R 486410 CDS YP_002996741.1 251782439 8110465 complement(1010049..1010336) 1 NC_012891.1 similar to ISSdy1, transposase OrfB [Streptococcus agalactiae 2603V/R]; ISSdy1, transposase OrfB 1010336 8110465 SDEG_1028 Streptococcus dysgalactiae subsp. equisimilis GGS_124 ISSdy1, transposase OrfB YP_002996741.1 1010049 R 486410 CDS YP_002996742.1 251782440 8110751 complement(1010454..1010567) 1 NC_012891.1 similar to ISSdy1, transposase OrfA [Streptococcus agalactiae 2603V/R]; ISSdy1, transposase OrfA 1010567 8110751 SDEG_1029 Streptococcus dysgalactiae subsp. equisimilis GGS_124 ISSdy1, transposase OrfA YP_002996742.1 1010454 R 486410 CDS YP_002996743.1 251782441 8110752 complement(1010636..1010743) 1 NC_012891.1 similar to transposase [Streptococcus agalactiae]; transposase 1010743 8110752 SDEG_1030 Streptococcus dysgalactiae subsp. equisimilis GGS_124 transposase YP_002996743.1 1010636 R 486410 CDS YP_002996744.1 251782442 8110753 complement(1010869..1011672) 1 NC_012891.1 similar to transposase [Streptococcus pyogenes str. Manfredo]; transposase 1011672 8110753 SDEG_1031 Streptococcus dysgalactiae subsp. equisimilis GGS_124 transposase YP_002996744.1 1010869 R 486410 CDS YP_002996745.1 251782443 8110754 complement(1011725..1011994) 1 NC_012891.1 similar to probable transposase TnpA (fragment) [Streptococcus pyogenes MGAS315]; transposase 1011994 tnpA 8110754 tnpA Streptococcus dysgalactiae subsp. equisimilis GGS_124 transposase YP_002996745.1 1011725 R 486410 CDS YP_002996746.1 251782444 8110528 complement(1012631..1014301) 1 NC_012891.1 catalyzes the formation of 10-formyltetrahydrofolate from formate and tetrahydrofolate; formate--tetrahydrofolate ligase 1014301 fhs1 8110528 fhs1 Streptococcus dysgalactiae subsp. equisimilis GGS_124 formate--tetrahydrofolate ligase YP_002996746.1 1012631 R 486410 CDS YP_002996747.1 251782445 8111890 complement(1014428..1015447) 1 NC_012891.1 similar to lipoate-protein ligase A [Streptococcus pyogenes MGAS10394]; lipoate-protein ligase A 1015447 lplA 8111890 lplA Streptococcus dysgalactiae subsp. equisimilis GGS_124 lipoate-protein ligase A YP_002996747.1 1014428 R 486410 CDS YP_002996748.1 251782446 8110906 complement(1015462..1016373) 1 NC_012891.1 similar to SIR2 family protein [Streptococcus pyogenes MGAS10394]; SIR2 family protein 1016373 8110906 SDEG_1035 Streptococcus dysgalactiae subsp. equisimilis GGS_124 SIR2 family protein YP_002996748.1 1015462 R 486410 CDS YP_002996749.1 251782447 8110755 complement(1016360..1017172) 1 NC_012891.1 similar to hypothetical protein M5005 Spy 0930 [Streptococcus pyogenes MGAS5005]; hypothetical protein 1017172 8110755 SDEG_1036 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996749.1 1016360 R 486410 CDS YP_002996750.1 251782448 8110756 complement(1017165..1017497) 1 NC_012891.1 similar to glycine cleavage system H protein [Streptococcus pyogenes MGAS5005]; glycine cleavage system H protein 1017497 8110756 SDEG_1037 Streptococcus dysgalactiae subsp. equisimilis GGS_124 glycine cleavage system H protein YP_002996750.1 1017165 R 486410 CDS YP_002996751.1 251782449 8110757 complement(1017729..1018928) 1 NC_012891.1 similar to probable NADH-dependent flavin oxidoreductase [Streptococcus pyogenes MGAS10394]; NADH-dependent flavin oxidoreductase 1018928 yqiG 8110757 yqiG Streptococcus dysgalactiae subsp. equisimilis GGS_124 NADH-dependent flavin oxidoreductase YP_002996751.1 1017729 R 486410 CDS YP_002996752.1 251782450 8111968 complement(1018928..1019761) 1 NC_012891.1 similar to lipoate-protein ligase A [Streptococcus pyogenes MGAS5005]; lipoate-protein ligase A 1019761 8111968 SDEG_1039 Streptococcus dysgalactiae subsp. equisimilis GGS_124 lipoate-protein ligase A YP_002996752.1 1018928 R 486410 CDS YP_002996753.1 251782451 8110758 1019978..1020670 1 NC_012891.1 similar to phosphopantothenate-cysteine ligase [Streptococcus pyogenes MGAS10270]; phosphopantothenate--cysteine ligase 1020670 dpfB 8110758 dpfB Streptococcus dysgalactiae subsp. equisimilis GGS_124 phosphopantothenate--cysteine ligase YP_002996753.1 1019978 D 486410 CDS YP_002996754.1 251782452 8111852 1020663..1021208 1 NC_012891.1 decarboxylates 4-phosphopantothenoylcysteine to form 4'-phosphopantotheine.; phosphopantothenoylcysteine decarboxylase 1021208 coaC 8111852 coaC Streptococcus dysgalactiae subsp. equisimilis GGS_124 phosphopantothenoylcysteine decarboxylase YP_002996754.1 1020663 D 486410 CDS YP_002996755.1 251782453 8111629 1021263..1021853 1 NC_012891.1 similar to integral membrane protein [Streptococcus pyogenes MGAS10750]; integral membrane protein 1021853 8111629 SDEG_1042 Streptococcus dysgalactiae subsp. equisimilis GGS_124 integral membrane protein YP_002996755.1 1021263 D 486410 CDS YP_002996756.1 251782454 8110759 1022016..1023734 1 NC_012891.1 similar to phosphomannomutase PgmA [Streptococcusequi subsp. zooepidemicus MGCS10565]; phosphomannomutase 1023734 pgmA 8110759 pgmA Streptococcus dysgalactiae subsp. equisimilis GGS_124 phosphomannomutase YP_002996756.1 1022016 D 486410 CDS YP_002996757.1 251782455 8111287 complement(1023902..1024870) 1 NC_012891.1 similar to nucleoside transport system permease protein [Streptococcus pyogenes MGAS10394]; nucleoside transport system permease 1024870 8111287 SDEG_1044 Streptococcus dysgalactiae subsp. equisimilis GGS_124 nucleoside transport system permease YP_002996757.1 1023902 R 486410 CDS YP_002996758.1 251782456 8110760 complement(1024860..1025924) 1 NC_012891.1 similar to nucleoside transportsystem permease protein [Streptococcus pyogenes MGAS6180]; nucleoside transport ATP-binding protein 1025924 8110760 SDEG_1045 Streptococcus dysgalactiae subsp. equisimilis GGS_124 nucleoside transport ATP-binding protein YP_002996758.1 1024860 R 486410 CDS YP_002996759.1 251782457 8110761 complement(1025917..1027467) 1 NC_012891.1 similar to nucleoside transport ATP-binding protein [Streptococcus pyogenes MGAS10270]; nucleoside transport ATP-binding protein 1027467 8110761 SDEG_1046 Streptococcus dysgalactiae subsp. equisimilis GGS_124 nucleoside transport ATP-binding protein YP_002996759.1 1025917 R 486410 CDS YP_002996760.1 251782458 8110762 complement(1027581..1028633) 1 NC_012891.1 similar to nucleoside-binding protein [Streptococcus pyogenes MGAS10394]; nucleoside-binding protein 1028633 8110762 SDEG_1047 Streptococcus dysgalactiae subsp. equisimilis GGS_124 nucleoside-binding protein YP_002996760.1 1027581 R 486410 CDS YP_002996761.1 251782459 8110763 complement(1028727..1029116) 1 NC_012891.1 Reclaims exogenous and endogenous cytidine and 2'-deoxycytidine molecules for UMP synthesis; cytidine deaminase 1029116 cdd 8110763 cdd Streptococcus dysgalactiae subsp. equisimilis GGS_124 cytidine deaminase YP_002996761.1 1028727 R 486410 CDS YP_002996762.1 251782460 8111610 complement(1029103..1029765) 1 NC_012891.1 catalyzes the formation of D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-D-ribose-5-phosphate; deoxyribose-phosphate aldolase 1029765 deoC 8111610 deoC Streptococcus dysgalactiae subsp. equisimilis GGS_124 deoxyribose-phosphate aldolase YP_002996762.1 1029103 R 486410 CDS YP_002996763.1 251782461 8111668 complement(1029781..1031058) 1 NC_012891.1 Catalyzes the reversible phosphorolysis of pyrimidines in the nucleotide synthesis salvage pathway; pyrimidine-nucleoside phosphorylase 1031058 pdp 8111668 pdp Streptococcus dysgalactiae subsp. equisimilis GGS_124 pyrimidine-nucleoside phosphorylase YP_002996763.1 1029781 R 486410 CDS YP_002996764.1 251782462 8111756 complement(1031045..1031677) 1 NC_012891.1 similar to 16S rRNA m(2)G 1207 methyltransferase [Streptococcus pyogenes MGAS10750]; 16S rRNA m(2)G 1207 methyltransferase 1031677 8111756 SDEG_1051 Streptococcus dysgalactiae subsp. equisimilis GGS_124 16S rRNA m(2)G 1207 methyltransferase YP_002996764.1 1031045 R 486410 CDS YP_002996765.1 251782463 8110764 1031913..1032833 1 NC_012891.1 catalyzes the formation of (R)-4'-phosphopantothenate in coenzyme A biosynthesis; pantothenate kinase 1032833 coaA 8110764 coaA Streptococcus dysgalactiae subsp. equisimilis GGS_124 pantothenate kinase YP_002996765.1 1031913 D 486410 CDS YP_002996766.1 251782464 8111628 1032887..1033135 1 NC_012891.1 binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase; 30S ribosomal protein S20 1033135 rpsT 8111628 rpsT Streptococcus dysgalactiae subsp. equisimilis GGS_124 30S ribosomal protein S20 YP_002996766.1 1032887 D 486410 CDS YP_002996767.1 251782465 8110448 complement(1033293..1034603) 1 NC_012891.1 similar to histidine kinase protein [Streptococcus pyogenes MGAS8232]; histidine kinase protein 1034603 8110448 SDEG_1054 Streptococcus dysgalactiae subsp. equisimilis GGS_124 histidine kinase protein YP_002996767.1 1033293 R 486410 CDS YP_002996768.1 251782466 8110765 complement(1034596..1035270) 1 NC_012891.1 similar to response regulator [Streptococcus pyogenes MGAS8232]; response regulator 1035270 8110765 SDEG_1055 Streptococcus dysgalactiae subsp. equisimilis GGS_124 response regulator YP_002996768.1 1034596 R 486410 CDS YP_002996769.1 251782467 8110766 complement(1035474..1038035) 1 NC_012891.1 similar to lysyl aminopeptidase / alanine aminopeptidase [Streptococcus pyogenes MGAS10750]; lysyl aminopeptidase/alanine aminopeptidase 1038035 pepN 8110766 pepN Streptococcus dysgalactiae subsp. equisimilis GGS_124 lysyl aminopeptidase/alanine aminopeptidase YP_002996769.1 1035474 R 486410 CDS YP_002996770.1 251782468 8111277 complement(1038212..1038865) 1 NC_012891.1 similar to phosphate transport system protein [Streptococcus pyogenes MGAS5005]; phosphate transport system protein 1038865 phoU 8111277 phoU Streptococcus dysgalactiae subsp. equisimilis GGS_124 phosphate transport system protein YP_002996770.1 1038212 R 486410 CDS YP_002996771.1 251782469 8111294 complement(1038943..1039704) 1 NC_012891.1 ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation; phosphate transporter ATP-binding protein 1039704 pstB 8111294 pstB Streptococcus dysgalactiae subsp. equisimilis GGS_124 phosphate transporter ATP-binding protein YP_002996771.1 1038943 R 486410 CDS YP_002996772.1 251782470 8111316 complement(1039714..1040517) 1 NC_012891.1 ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation; phosphate transporter ATP-binding protein 1040517 pstB2 8111316 pstB2 Streptococcus dysgalactiae subsp. equisimilis GGS_124 phosphate transporter ATP-binding protein YP_002996772.1 1039714 R 486410 CDS YP_002996773.1 251782471 8111317 complement(1040533..1041420) 1 NC_012891.1 similar to phosphate transport system permease protein [Streptococcus pyogenes MGAS5005]; phosphate ABC transporter permease 1041420 pstA 8111317 pstA Streptococcus dysgalactiae subsp. equisimilis GGS_124 phosphate ABC transporter permease YP_002996773.1 1040533 R 486410 CDS YP_002996774.1 251782472 8111315 complement(1041410..1042345) 1 NC_012891.1 similar to phosphate transport system permease protein pstC [Streptococcus pyogenes MGAS10750]; phosphate ABC transporter permease 1042345 pstC 8111315 pstC Streptococcus dysgalactiae subsp. equisimilis GGS_124 phosphate ABC transporter permease YP_002996774.1 1041410 R 486410 CDS YP_002996775.1 251782473 8111318 complement(1042356..1043222) 1 NC_012891.1 similar to phosphate-binding protein [Streptococcus pyogenes MGAS5005]; phosphate-binding protein 1043222 pstS 8111318 pstS Streptococcus dysgalactiae subsp. equisimilis GGS_124 phosphate-binding protein YP_002996775.1 1042356 R 486410 CDS YP_002996776.1 251782474 8111320 complement(1043362..1044672) 1 NC_012891.1 similar to 23S rRNA m(5)C methyltransferase [Streptococcus pyogenes MGAS10750]; 23S rRNA m(5)C methyltransferase 1044672 8111320 SDEG_1063 Streptococcus dysgalactiae subsp. equisimilis GGS_124 23S rRNA m(5)C methyltransferase YP_002996776.1 1043362 R 486410 CDS YP_002996777.1 251782475 8110767 complement(1044688..1045467) 1 NC_012891.1 similar to myo-inositol-1(or 4)-monophosphatase [Streptococcus pyogenes MGAS8232]; myo-inositol-1(or 4)-monophosphatase 1045467 8110767 SDEG_1064 Streptococcus dysgalactiae subsp. equisimilis GGS_124 myo-inositol-1(or 4)-monophosphatase YP_002996777.1 1044688 R 486410 CDS YP_002996778.1 251782476 8110768 complement(1045457..1045735) 1 NC_012891.1 similar to hypothetical protein M6 Spy0948 [Streptococcus pyogenes MGAS10394]; hypothetical protein 1045735 8110768 SDEG_1065 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996778.1 1045457 R 486410 CDS YP_002996779.1 251782477 8110769 complement(1045737..1046141) 1 NC_012891.1 the anti-alpha factor Spx interacts with RNA polymerase alpha subunit C-terminal domain in a region that interacts with the sigma 70 subunit and may interfere with activation of promoters; in Bacillus subtilis this protein is a substrate for ClpXP protease; blocks transcription of the competence regulatory gene encoded by the srf operon; regulates a number of genes involved in thiol homeostasis including trxA and trxB; monomeric member of ArsC family of proteins; does not bind DNA; contains a disulfide bond between C10 and C13 which may sense disulfide stress; transcriptional regulator Spx 1046141 spxA 8110769 spxA Streptococcus dysgalactiae subsp. equisimilis GGS_124 transcriptional regulator Spx YP_002996779.1 1045737 R 486410 CDS YP_002996780.1 251782478 8110501 complement(1046184..1047116) 1 NC_012891.1 catalyzes the formation of FMN from riboflavin and the formation of FAD from FMN; in Bacillus the ribC gene has both flavokinase and FAD synthetase activities; bifunctional riboflavin kinase/FMN adenylyltransferase 1047116 ribC 8110501 ribC Streptococcus dysgalactiae subsp. equisimilis GGS_124 bifunctional riboflavin kinase/FMN adenylyltransferase YP_002996780.1 1046184 R 486410 CDS YP_002996781.1 251782479 8111049 complement(1047154..1047540) 1 NC_012891.1 similar to transposase [Streptococcus criceti]; transposase 1047540 paaB 8111049 paaB Streptococcus dysgalactiae subsp. equisimilis GGS_124 transposase YP_002996781.1 1047154 R 486410 CDS YP_002996782.1 251782480 8111746 complement(1047597..1048016) 1 NC_012891.1 similar to transposase [Streptococcus pyogenes MGAS2096]; transposase 1048016 8111746 SDEG_1069 Streptococcus dysgalactiae subsp. equisimilis GGS_124 transposase YP_002996782.1 1047597 R 486410 CDS YP_002996783.1 251782481 8110770 complement(1048111..1048995) 1 NC_012891.1 catalyzes isomerization of specific uridines in RNA to pseudouridine; responsible for residues in T loops of many tRNAs; tRNA pseudouridine synthase B 1048995 truB 8110770 truB Streptococcus dysgalactiae subsp. equisimilis GGS_124 tRNA pseudouridine synthase B YP_002996783.1 1048111 R 486410 CDS YP_002996784.1 251782482 8111931 complement(1049111..1050451) 1 NC_012891.1 similar to COG4487, uncharacterized protein conserved in bacteria [Streptococcus pyogenes M49 591]; hypothetical protein 1050451 8111931 SDEG_1071 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996784.1 1049111 R 486410 CDS YP_002996785.1 251782483 8110771 complement(1050557..1051513) 1 NC_012891.1 similar to integral membrane protein [Streptococcus pyogenes MGAS10750]; integral membrane protein 1051513 8110771 SDEG_1072 Streptococcus dysgalactiae subsp. equisimilis GGS_124 integral membrane protein YP_002996785.1 1050557 R 486410 CDS YP_002996786.1 251782484 8110949 complement(1051524..1052120) 1 NC_012891.1 similar to hypothetical protein SpyM3 0890 [Streptococcus pyogenes MGAS315]; hypothetical protein 1052120 8110949 SDEG_1073 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996786.1 1051524 R 486410 CDS YP_002996787.1 251782485 8110950 complement(1052202..1054847) 1 NC_012891.1 similar to ABC transporter permease protein [Streptococcus pyogenes MGAS2096]; ABC transporter permease 1054847 8110950 SDEG_1074 Streptococcus dysgalactiae subsp. equisimilis GGS_124 ABC transporter permease YP_002996787.1 1052202 R 486410 CDS YP_002996788.1 251782486 8110951 complement(1054857..1055558) 1 NC_012891.1 similar to ABC transporter (ATP-binding protein) [Streptococcus pyogenes MGAS8232]; ABC transporter ATP-binding protein 1055558 8110951 SDEG_1075 Streptococcus dysgalactiae subsp. equisimilis GGS_124 ABC transporter ATP-binding protein YP_002996788.1 1054857 R 486410 CDS YP_002996789.1 251782487 8110952 1055678..1056229 1 NC_012891.1 similar to TetR family transcriptional regulator [Streptococcus pyogenes MGAS10270]; TetR family transcriptional regulator 1056229 tetR 8110952 tetR Streptococcus dysgalactiae subsp. equisimilis GGS_124 TetR family transcriptional regulator YP_002996789.1 1055678 D 486410 CDS YP_002996790.1 251782488 8110515 complement(1056346..1056987) 1 NC_012891.1 similar to transcriptional regulator [Streptococcus pyogenes M1 GAS]; transcriptional regulator 1056987 8110515 SDEG_1077 Streptococcus dysgalactiae subsp. equisimilis GGS_124 transcriptional regulator YP_002996790.1 1056346 R 486410 CDS YP_002996791.1 251782489 8110953 complement(1057147..1057635) 1 NC_012891.1 similar to Gls24 family general stress protein [Streptococcus pyogenes MGAS10394]; Gls24 family general stress protein 1057635 8110953 SDEG_1078 Streptococcus dysgalactiae subsp. equisimilis GGS_124 Gls24 family general stress protein YP_002996791.1 1057147 R 486410 CDS YP_002996792.1 251782490 8110954 complement(1057901..1058440) 1 NC_012891.1 similar to hypothetical protein SpyM50827 [Streptococcus pyogenes str. Manfredo]; hypothetical protein 1058440 8110954 SDEG_1079 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996792.1 1057901 R 486410 CDS YP_002996793.1 251782491 8110955 complement(1058464..1058652) 1 NC_012891.1 similar to hypothetical protein SPy 1263 [Streptococcus pyogenes M1 GAS]; hypothetical protein 1058652 8110955 SDEG_1080 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996793.1 1058464 R 486410 CDS YP_002996794.1 251782492 8110956 complement(1058663..1059244) 1 NC_012891.1 similar to hypothetical protein spyM18 1215 [Streptococcus pyogenes MGAS8232]; hypothetical protein 1059244 8110956 SDEG_1081 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996794.1 1058663 R 486410 CDS YP_002996795.1 251782493 8110957 complement(1059305..1059553) 1 NC_012891.1 similar to hypothetical protein SpyM50824 [Streptococcus pyogenes str. Manfredo]; hypothetical protein 1059553 8110957 SDEG_1082 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996795.1 1059305 R 486410 CDS YP_002996796.1 251782494 8110958 complement(1059923..1062241) 1 NC_012891.1 similar to DNA helicase II [Streptococcus pyogenes MGAS10394]; DNA helicase II 1062241 8110958 SDEG_1083 Streptococcus dysgalactiae subsp. equisimilis GGS_124 DNA helicase II YP_002996796.1 1059923 R 486410 CDS YP_002996797.1 251782495 8110959 1062762..1064099 1 NC_012891.1 similar to amino acid symporter [Streptococcus pyogenes MGAS315]; amino acid symporter 1064099 8110959 SDEG_1084 Streptococcus dysgalactiae subsp. equisimilis GGS_124 amino acid symporter YP_002996797.1 1062762 D 486410 CDS YP_002996798.1 251782496 8110960 1064205..1065440 1 NC_012891.1 similar to cobalt-zinc-cadmium resistance protein czcD [Streptococcus pyogenes MGAS10270]; cobalt-zinc-cadmium resistance protein 1065440 czcD 8110960 czcD Streptococcus dysgalactiae subsp. equisimilis GGS_124 cobalt-zinc-cadmium resistance protein YP_002996798.1 1064205 D 486410 CDS YP_002996799.1 251782497 8111659 complement(1065476..1065877) 1 NC_012891.1 similar to transposase [Streptococcus pyogenes MGAS10394]; transposase 1065877 8111659 SDEG_1086 Streptococcus dysgalactiae subsp. equisimilis GGS_124 transposase YP_002996799.1 1065476 R 486410 CDS YP_002996800.1 251782498 8110961 complement(1065720..1066919) 1 NC_012891.1 similar to transposase [Streptococcus pyogenes MGAS10394]; transposase 1066919 8110961 SDEG_1087 Streptococcus dysgalactiae subsp. equisimilis GGS_124 transposase YP_002996800.1 1065720 R 486410 CDS YP_002996801.1 251782499 8110962 complement(1067151..1067993) 1 NC_012891.1 similar to amino acid ABC transporter extracellular-binding protein precursor [Streptococcus equi subsp. zooepidemicus MGCS10565]; amino acid ABC transporter substrate-binding protein 1067993 8110962 SDEG_1088 Streptococcus dysgalactiae subsp. equisimilis GGS_124 amino acid ABC transporter substrate-binding protein YP_002996801.1 1067151 R 486410 CDS YP_002996802.1 251782500 8110963 complement(1068006..1068635) 1 NC_012891.1 similar to histidine transport ATP-binding protein hisP [Streptococcus pyogenes MGAS10750]; histidine ABC transporter ATP-binding protein 1068635 8110963 SDEG_1089 Streptococcus dysgalactiae subsp. equisimilis GGS_124 histidine ABC transporter ATP-binding protein YP_002996802.1 1068006 R 486410 CDS YP_002996803.1 251782501 8110964 complement(1068645..1069286) 1 NC_012891.1 similar to histidine transport system permease protein hisM [Streptococcus pyogenes MGAS10270]; histidine transport system permease 1069286 hisM 8110964 hisM Streptococcus dysgalactiae subsp. equisimilis GGS_124 histidine transport system permease YP_002996803.1 1068645 R 486410 CDS YP_002996804.1 251782502 8112031 complement(1069393..1069728) 1 NC_012891.1 similar to hypothetical protein spyM18 1226 [Streptococcus pyogenes MGAS8232]; hypothetical protein 1069728 8112031 SDEG_1091 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996804.1 1069393 R 486410 CDS YP_002996805.1 251782503 8110965 complement(1069926..1071740) 1 NC_012891.1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source; glucosamine--fructose-6-phosphate aminotransferase 1071740 glmS 8110965 glmS Streptococcus dysgalactiae subsp. equisimilis GGS_124 glucosamine--fructose-6-phosphate aminotransferase YP_002996805.1 1069926 R 486410 CDS YP_002996806.1 251782504 8112001 complement(1071924..1072481) 1 NC_012891.1 similar to signal peptidase I [Streptococcus pyogenes MGAS2096]; signal peptidase I 1072481 sipC 8112001 sipC Streptococcus dysgalactiae subsp. equisimilis GGS_124 signal peptidase I YP_002996806.1 1071924 R 486410 CDS YP_002996807.1 251782505 8110487 complement(1072647..1074149) 1 NC_012891.1 catalyzes the formation of phosphoenolpyruvate from pyruvate; pyruvate kinase 1074149 pyk 8110487 pyk Streptococcus dysgalactiae subsp. equisimilis GGS_124 pyruvate kinase YP_002996807.1 1072647 R 486410 CDS YP_002996808.1 251782506 8111337 complement(1074212..1075225) 1 NC_012891.1 catalyzes the formation of D-fructose 1,6-bisphosphate from D-fructose 6-phosphate in glycolysis; 6-phosphofructokinase 1075225 pfkA 8111337 pfkA Streptococcus dysgalactiae subsp. equisimilis GGS_124 6-phosphofructokinase YP_002996808.1 1074212 R 486410 CDS YP_002996809.1 251782507 8111283 complement(1075305..1078415) 1 NC_012891.1 Catalyzes DNA-template-directed extension of the 3'-end of a DNA strand by one nucleotide at a time. Proposed to be responsible for the synthesis of the lagging strand. In the low GC gram positive bacteria this enzyme is less processive and more error prone than its counterpart in other bacteria.; DNA polymerase III DnaE 1078415 dnaE 8111283 dnaE Streptococcus dysgalactiae subsp. equisimilis GGS_124 DNA polymerase III DnaE YP_002996809.1 1075305 R 486410 CDS YP_002996810.1 251782508 8111845 1078602..1078973 1 NC_012891.1 similar to transcriptional regulator GntR family [Streptococcus pyogenes MGAS10750]; GntR family transcriptional regulator 1078973 8111845 SDEG_1097 Streptococcus dysgalactiae subsp. equisimilis GGS_124 GntR family transcriptional regulator YP_002996810.1 1078602 D 486410 CDS YP_002996811.1 251782509 8110966 1078973..1079671 1 NC_012891.1 similar to ABC transporter ATP-binding protein [Streptococcus pyogenes str. Manfredo]; ABC transporter ATP-binding protein 1079671 8110966 SDEG_1098 Streptococcus dysgalactiae subsp. equisimilis GGS_124 ABC transporter ATP-binding protein YP_002996811.1 1078973 D 486410 CDS YP_002996812.1 251782510 8110967 1079681..1080469 1 NC_012891.1 similar to hypothetical protein SpyM3 0917 [Streptococcus pyogenes MGAS315]; hypothetical protein 1080469 8110967 SDEG_1099 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996812.1 1079681 D 486410 CDS YP_002996813.1 251782511 8110968 complement(1080605..1081219) 1 NC_012891.1 similar to hypothetical protein spyM18 1236 [Streptococcus pyogenes MGAS8232]; hypothetical protein 1081219 8110968 SDEG_1100 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996813.1 1080605 R 486410 CDS YP_002996815.1 251782513 8110970 complement(1081810..1081998) 1 NC_012891.1 similar to unknown phage protein [Streptococcus pyogenes MGAS10394]; phage protein 1081998 8110970 SDEG_1102 Streptococcus dysgalactiae subsp. equisimilis GGS_124 phage protein YP_002996815.1 1081810 R 486410 CDS YP_002996816.1 251782514 8110971 1082237..1083220 1 NC_012891.1 similar to deoxyribonuclease [Streptococcus dysgalactiae subsp. equisimilis]; deoxyribonuclease 1083220 sdc 8110971 sdc Streptococcus dysgalactiae subsp. equisimilis GGS_124 deoxyribonuclease YP_002996816.1 1082237 D 486410 CDS YP_002996817.1 251782515 8110473 complement(1083282..1083482) 1 NC_012891.1 similar to CsbD-like phage protein [Streptococcus pyogenes str. Manfredo]; CsbD-like phage protein 1083482 8110473 SDEG_1104 Streptococcus dysgalactiae subsp. equisimilis GGS_124 CsbD-like phage protein YP_002996817.1 1083282 R 486410 CDS YP_002996818.1 251782516 8110972 complement(1083671..1084183) 1 NC_012891.1 similar to hypothetical protein CGSSp14BS69 08645 [Streptococcus pneumoniae SP14-BS69]; hypothetical protein 1084183 8110972 SDEG_1105 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996818.1 1083671 R 486410 CDS YP_002996819.1 251782517 8110973 complement(1084580..1085782) 1 NC_012891.1 similar to lysin [Streptococcus phage P9]; lysin 1085782 8110973 SDEG_1106 Streptococcus dysgalactiae subsp. equisimilis GGS_124 lysin YP_002996819.1 1084580 R 486410 CDS YP_002996820.1 251782518 8110974 complement(1085770..1085892) 1 NC_012891.1 similar to hypothetical protein P9 gp49 [Streptococcus phage P9]; hypothetical protein 1085892 8110974 SDEG_1107 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996820.1 1085770 R 486410 CDS YP_002996821.1 251782519 8110975 complement(1085894..1086349) 1 NC_012891.1 similar to Holin [Streptococcus pyogenes MGAS10394]; holin 1086349 8110975 SDEG_1108 Streptococcus dysgalactiae subsp. equisimilis GGS_124 holin YP_002996821.1 1085894 R 486410 CDS YP_002996822.1 251782520 8110976 complement(1086352..1087008) 1 NC_012891.1 similar to phage protein [Streptococcus pyogenes MGAS10750]; phage protein 1087008 8110976 SDEG_1109 Streptococcus dysgalactiae subsp. equisimilis GGS_124 phage protein YP_002996822.1 1086352 R 486410 CDS YP_002996823.1 251782521 8110977 complement(1087011..1087439) 1 NC_012891.1 similar to hypothetical protein spyM18 1755 [Streptococcus pyogenes MGAS8232]; hypothetical protein 1087439 8110977 SDEG_1110 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996823.1 1087011 R 486410 CDS YP_002996824.1 251782522 8110978 complement(1087449..1089158) 1 NC_012891.1 similar to hypothetical protein SpyM50681 [Streptococcus pyogenes str. Manfredo]; hypothetical protein 1089158 8110978 SDEG_1111 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996824.1 1087449 R 486410 CDS YP_002996825.1 251782523 8110979 complement(1089167..1089820) 1 NC_012891.1 similar to phage protein [Streptococcus phage 10270.2]; phage protein 1089820 8110979 SDEG_1112 Streptococcus dysgalactiae subsp. equisimilis GGS_124 phage protein YP_002996825.1 1089167 R 486410 CDS YP_002996826.1 251782524 8110980 complement(1089820..1090605) 1 NC_012891.1 similar to hyaluronoglucosaminidase [Streptococcus pyogenes MGAS10394]; hyaluronoglucosaminidase 1090605 8110980 SDEG_1113 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hyaluronoglucosaminidase YP_002996826.1 1089820 R 486410 CDS YP_002996827.1 251782525 8110981 complement(1090602..1091813) 1 NC_012891.1 probable C-terminal portion of phage endopeptidase [Streptococcus pyogenes MGAS10394]; phage endopeptidase 1091813 8110981 SDEG_1114 Streptococcus dysgalactiae subsp. equisimilis GGS_124 phage endopeptidase YP_002996827.1 1090602 R 486410 CDS YP_002996828.1 251782526 8110982 complement(1091870..1092544) 1 NC_012891.1 probable N-terminal portion of phage endopeptidase [Streptococcus pyogenes MGAS10394]; phage endopeptidase 1092544 8110982 SDEG_1115 Streptococcus dysgalactiae subsp. equisimilis GGS_124 phage endopeptidase YP_002996828.1 1091870 R 486410 CDS YP_002996829.1 251782527 8110983 complement(1092541..1093236) 1 NC_012891.1 similar to hypothetical protein spyM18 1457 [Streptococcus pyogenes MGAS8232]; hypothetical protein 1093236 8110983 SDEG_1116 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996829.1 1092541 R 486410 CDS YP_002996830.1 251782528 8110984 complement(1093233..1095083) 1 NC_012891.1 similar to phage protein [Streptococcus pyogenes MGAS5005]; phage protein 1095083 8110984 SDEG_1117 Streptococcus dysgalactiae subsp. equisimilis GGS_124 phage protein YP_002996830.1 1093233 R 486410 CDS YP_002996831.1 251782529 8110985 complement(1095252..1095812) 1 NC_012891.1 similar to endodeoxyribonuclease [Lactococcus phage r1t]; endodeoxyribonuclease 1095812 8110985 SDEG_1118 Streptococcus dysgalactiae subsp. equisimilis GGS_124 endodeoxyribonuclease YP_002996831.1 1095252 R 486410 CDS YP_002996832.1 251782530 8110986 complement(1095899..1096489) 1 NC_012891.1 similar to N-terminal of phage protein [Streptococcus pyogenes MGAS5005]; phage protein 1096489 8110986 SDEG_1119 Streptococcus dysgalactiae subsp. equisimilis GGS_124 phage protein YP_002996832.1 1095899 R 486410 CDS YP_002996833.1 251782531 8110987 complement(1096489..1096860) 1 NC_012891.1 similar to phage protein [Streptococcus pyogenes MGAS5005]; phage protein 1096860 8110987 SDEG_1120 Streptococcus dysgalactiae subsp. equisimilis GGS_124 phage protein YP_002996833.1 1096489 R 486410 CDS YP_002996834.1 251782532 8110988 complement(1097149..1097745) 1 NC_012891.1 similar to major tail protein [Streptococcus pyogenes MGAS5005]; major tail protein 1097745 8110988 SDEG_1121 Streptococcus dysgalactiae subsp. equisimilis GGS_124 major tail protein YP_002996834.1 1097149 R 486410 CDS YP_002996835.1 251782533 8110989 complement(1097754..1098089) 1 NC_012891.1 similar to unknown phage protein [Streptococcus pyogenes MGAS10394]; phage protein 1098089 8110989 SDEG_1122 Streptococcus dysgalactiae subsp. equisimilis GGS_124 phage protein YP_002996835.1 1097754 R 486410 CDS YP_002996836.1 251782534 8110990 complement(1098090..1098335) 1 NC_012891.1 similar to unknown phage protein [Streptococcus pyogenes MGAS10394]; phage protein 1098335 8110990 SDEG_1123 Streptococcus dysgalactiae subsp. equisimilis GGS_124 phage protein YP_002996836.1 1098090 R 486410 CDS YP_002996837.1 251782535 8110991 complement(1098319..1098657) 1 NC_012891.1 similar to phage protein [Streptococcus pyogenes MGAS5005]; phage protein 1098657 8110991 SDEG_1124 Streptococcus dysgalactiae subsp. equisimilis GGS_124 phage protein YP_002996837.1 1098319 R 486410 CDS YP_002996838.1 251782536 8110992 complement(1098620..1099039) 1 NC_012891.1 similar to phage protein [Streptococcus pyogenes MGAS5005]; phage protein 1099039 8110992 SDEG_1125 Streptococcus dysgalactiae subsp. equisimilis GGS_124 phage protein YP_002996838.1 1098620 R 486410 CDS YP_002996839.1 251782537 8110993 complement(1099060..1099293) 1 NC_012891.1 similar to conserved hypothetical protein (phage associated) [Streptococcus suis 89/1591]; hypothetical protein 1099293 8110993 SDEG_1126 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996839.1 1099060 R 486410 CDS YP_002996840.1 251782538 8110994 complement(1099295..1100188) 1 NC_012891.1 similar to structural protein - phage associated [Streptococcus suis 89 /1591]; phage associated structural protein 1100188 8110994 SDEG_1127 Streptococcus dysgalactiae subsp. equisimilis GGS_124 phage associated structural protein YP_002996840.1 1099295 R 486410 CDS YP_002996841.1 251782539 8110995 complement(1100206..1100793) 1 NC_012891.1 similar to phage protein [Streptococcus pyogenes MGAS10750]; phage protein 1100793 8110995 SDEG_1128 Streptococcus dysgalactiae subsp. equisimilis GGS_124 phage protein YP_002996841.1 1100206 R 486410 CDS YP_002996842.1 251782540 8110996 complement(1100726..1102156) 1 NC_012891.1 similar to phage terminase [Streptococcus pyogenes MGAS10750]; phage terminase 1102156 8110996 SDEG_1129 Streptococcus dysgalactiae subsp. equisimilis GGS_124 phage terminase YP_002996842.1 1100726 R 486410 CDS YP_002996843.1 251782541 8110997 complement(1102205..1102474) 1 NC_012891.1 similar to hypothetical protein spyM18 1273 [Streptococcus pyogenes MGAS8232]; hypothetical protein 1102474 8110997 SDEG_1130 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996843.1 1102205 R 486410 CDS YP_002996844.1 251782542 8110998 complement(1102536..1102733) 1 NC_012891.1 similar to hypothetical protein MGAS10750 Spy1919 [bacteriophage 10750.4]; hypothetical protein 1102733 8110998 SDEG_1131 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996844.1 1102536 R 486410 CDS YP_002996845.1 251782543 8110999 complement(1102733..1103944) 1 NC_012891.1 similar to hypothetical protein SAK 0633 [Streptococcus agalactiae A909]; hypothetical protein 1103944 8110999 SDEG_1132 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996845.1 1102733 R 486410 CDS YP_002996846.1 251782544 8111000 complement(1103937..1105205) 1 NC_012891.1 similar to structural phage protein [Streptococcus pyogenes MGAS8232]; structural phage protein 1105205 8111000 SDEG_1133 Streptococcus dysgalactiae subsp. equisimilis GGS_124 structural phage protein YP_002996846.1 1103937 R 486410 CDS YP_002996847.1 251782545 8111001 complement(1105202..1105558) 1 NC_012891.1 similar to hypothetical protein spyM18 1482 [Streptococcus pyogenes MGAS8232]; hypothetical protein 1105558 8111001 SDEG_1134 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996847.1 1105202 R 486410 CDS YP_002996848.1 251782546 8111002 complement(1105706..1106050) 1 NC_012891.1 similar to HNH endonuclease family protein [Streptococcus pyogenes MGAS5005]; hypothetical protein 1106050 8111002 SDEG_1135 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996848.1 1105706 R 486410 CDS YP_002996849.1 251782547 8111003 complement(1106158..1106577) 1 NC_012891.1 similar to hypothetical protein spyM18 1485 [Streptococcus pyogenes MGAS8232]; hypothetical protein 1106577 8111003 SDEG_1136 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996849.1 1106158 R 486410 CDS YP_002996850.1 251782548 8111004 complement(1106653..1106904) 1 NC_012891.1 similar to hypothetical protein SpyM3 1125 [Streptococcus pyogenes MGAS315]; hypothetical protein 1106904 8111004 SDEG_1137 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996850.1 1106653 R 486410 CDS YP_002996851.1 251782549 8111005 complement(1106918..1107187) 1 NC_012891.1 similar to phage protein [bacteriophage 10750.2]; phage protein 1107187 8111005 SDEG_1138 Streptococcus dysgalactiae subsp. equisimilis GGS_124 phage protein YP_002996851.1 1106918 R 486410 CDS YP_002996852.1 251782550 8111006 complement(1107184..1107375) 1 NC_012891.1 similar to phage protein [bacteriophage 10750.1]; phage protein 1107375 8111006 SDEG_1139 Streptococcus dysgalactiae subsp. equisimilis GGS_124 phage protein YP_002996852.1 1107184 R 486410 CDS YP_002996853.1 251782551 8111007 complement(1107362..1107874) 1 NC_012891.1 similar to phage protein [Streptococcus pyogenes MGAS5005]; phage protein 1107874 8111007 SDEG_1140 Streptococcus dysgalactiae subsp. equisimilis GGS_124 phage protein YP_002996853.1 1107362 R 486410 CDS YP_002996854.1 251782552 8111008 complement(1107871..1108212) 1 NC_012891.1 similar to hypothetical protein spyM18 0734 [Streptococcus pyogenes MGAS8232]; hypothetical protein 1108212 8111008 SDEG_1141 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996854.1 1107871 R 486410 CDS YP_002996855.1 251782553 8111009 complement(1108387..1108554) 1 NC_012891.1 similar to phage protein [Streptococcus pyogenes MGAS5005]; phage protein 1108554 8111009 SDEG_1142 Streptococcus dysgalactiae subsp. equisimilis GGS_124 phage protein YP_002996855.1 1108387 R 486410 CDS YP_002996856.1 251782554 8111010 complement(1108564..1109361) 1 NC_012891.1 similar to hypothetical protein spyM18 1494 [Streptococcus pyogenes MGAS8232]; hypothetical protein 1109361 8111010 SDEG_1143 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996856.1 1108564 R 486410 CDS YP_002996857.1 251782555 8111011 complement(1109354..1109554) 1 NC_012891.1 similar to hypothetical protein spyM18 0732 [Streptococcus pyogenes MGAS8232]; hypothetical protein 1109554 8111011 SDEG_1144 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996857.1 1109354 R 486410 CDS YP_002996858.1 251782556 8111012 complement(1109551..1110477) 1 NC_012891.1 similar to recT protein [Streptococcus pyogenes MGAS5005]; recT protein 1110477 8111012 SDEG_1145 Streptococcus dysgalactiae subsp. equisimilis GGS_124 recT protein YP_002996858.1 1109551 R 486410 CDS YP_002996859.1 251782557 8111013 complement(1110638..1110844) 1 NC_012891.1 similar to hypothetical protein SPy 0956 [Streptococcus phage 370.3]; hypothetical protein 1110844 8111013 SDEG_1146 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996859.1 1110638 R 486410 CDS YP_002996860.1 251782558 8111014 complement(1110853..1110993) 1 NC_012891.1 similar to phage protein [Streptococcus pyogenes MGAS10270]; phage protein 1110993 8111014 SDEG_1147 Streptococcus dysgalactiae subsp. equisimilis GGS_124 phage protein YP_002996860.1 1110853 R 486410 CDS YP_002996861.1 251782559 8111015 complement(1110990..1111223) 1 NC_012891.1 similar to hypothetical protein spyM18 1499 [Streptococcus pyogenes MGAS8232]; hypothetical protein 1111223 8111015 SDEG_1148 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996861.1 1110990 R 486410 CDS YP_002996862.1 251782560 8111016 complement(1111204..1111590) 1 NC_012891.1 similar to phage DNA replication protein [Streptococcus pyogenes str. Manfredo]; phage DNA replication protein 1111590 8111016 SDEG_1149 Streptococcus dysgalactiae subsp. equisimilis GGS_124 phage DNA replication protein YP_002996862.1 1111204 R 486410 CDS YP_002996863.1 251782561 8111017 complement(1111729..1111980) 1 NC_012891.1 similar to phage replication protein [Streptococcus pyogenes MGAS5005]; phage replication protein 1111980 8111017 SDEG_1150 Streptococcus dysgalactiae subsp. equisimilis GGS_124 phage replication protein YP_002996863.1 1111729 R 486410 CDS YP_002996864.1 251782562 8111018 complement(1112080..1112265) 1 NC_012891.1 similar to hypothetical protein SPy 0952 [Streptococcus phage 370.3]; hypothetical protein 1112265 8111018 SDEG_1151 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996864.1 1112080 R 486410 CDS YP_002996865.1 251782563 8111019 complement(1112267..1112557) 1 NC_012891.1 similar to phage protein [Streptococcus pyogenes MGAS6180]; phage protein 1112557 8111019 SDEG_1152 Streptococcus dysgalactiae subsp. equisimilis GGS_124 phage protein YP_002996865.1 1112267 R 486410 CDS YP_002996866.1 251782564 8111020 complement(1112847..1113050) 1 NC_012891.1 similar to unknown phage protein [Streptococcus pyogenes MGAS10394]; phage protein 1113050 8111020 SDEG_1153 Streptococcus dysgalactiae subsp. equisimilis GGS_124 phage protein YP_002996866.1 1112847 R 486410 CDS YP_002996867.1 251782565 8111021 1113108..1113521 1 NC_012891.1 similar to phage protein [Streptococcus pyogenes phage 5005.3]; phage protein 1113521 8111021 SDEG_1154 Streptococcus dysgalactiae subsp. equisimilis GGS_124 phage protein YP_002996867.1 1113108 D 486410 CDS YP_002996868.1 251782566 8111022 complement(1113694..1113909) 1 NC_012891.1 similar to hypothetical protein SpyM50635 [Streptococcus pyogenes str. Manfredo]; hypothetical protein 1113909 8111022 SDEG_1155 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996868.1 1113694 R 486410 CDS YP_002996869.1 251782567 8111023 1114216..1114566 1 NC_012891.1 similar to phage DNA-binding protein [Streptococcus pyogenes str. Manfredo]; phage DNA-binding protein 1114566 8111023 SDEG_1156 Streptococcus dysgalactiae subsp. equisimilis GGS_124 phage DNA-binding protein YP_002996869.1 1114216 D 486410 CDS YP_002996870.1 251782568 8111024 1114569..1114955 1 NC_012891.1 similar to hypothetical protein SpyM50633 [Streptococcus pyogenes str. Manfredo]; hypothetical protein 1114955 8111024 SDEG_1157 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996870.1 1114569 D 486410 CDS YP_002996871.1 251782569 8111025 1114966..1115388 1 NC_012891.1 similar to hypothetical protein CGSSp6BS73 08144 [Streptococcus pneumoniae SP6-BS73]; hypothetical protein 1115388 8111025 SDEG_1158 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996871.1 1114966 D 486410 CDS YP_002996872.1 251782570 8111026 1115394..1115867 1 NC_012891.1 similar to hypothetical protein CGSSp6BS73 08139 [Streptococcus pneumoniae SP6-BS73]; hypothetical protein 1115867 8111026 SDEG_1159 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996872.1 1115394 D 486410 CDS YP_002996873.1 251782571 8111027 1115991..1117079 1 NC_012891.1 similar to integrase [Streptococcus pyogenes MGAS8232]; integrase 1117079 int 8111027 int Streptococcus dysgalactiae subsp. equisimilis GGS_124 integrase YP_002996873.1 1115991 D 486410 CDS YP_002996874.1 251782572 8110869 1117436..1118062 1 NC_012891.1 similar to hypothetical protein M5005 Spy 1054 [Streptococcus pyogenes phage 5005.1]; hypothetical protein 1118062 8110869 SDEG_1161 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996874.1 1117436 D 486410 CDS YP_002996875.1 251782573 8111028 complement(1118158..1118592) 1 NC_012891.1 similar to transposase [Streptococcus pyogenes MGAS10394]; transposase 1118592 8111028 SDEG_1162 Streptococcus dysgalactiae subsp. equisimilis GGS_124 transposase YP_002996875.1 1118158 R 486410 CDS YP_002996876.1 251782574 8111029 complement(1118420..1119619) 1 NC_012891.1 similar to transposase; Phage-associated cell wall hydrolase [Streptococcus pyogenes MGAS10394]; transposase 1119619 8111029 SDEG_1163 Streptococcus dysgalactiae subsp. equisimilis GGS_124 transposase YP_002996876.1 1118420 R 486410 CDS YP_002996877.1 251782575 8111517 complement(1119925..1121130) 1 NC_012891.1 in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins; 30S ribosomal protein S1 1121130 rpsA 8111517 rpsA Streptococcus dysgalactiae subsp. equisimilis GGS_124 30S ribosomal protein S1 YP_002996877.1 1119925 R 486410 CDS YP_002996879.1 251782576 8111519 complement(1121519..1121749) 1 NC_012891.1 similar to hypothetical cytosolic protein [Streptococcus pyogenes MGAS10750]; hypothetical protein 1121749 8111519 SDEG_1169 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996879.1 1121519 R 486410 CDS YP_002996880.1 251782577 8111520 complement(1121813..1122838) 1 NC_012891.1 catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids; branched-chain amino acid aminotransferase 1122838 bcaT 8111520 bcaT Streptococcus dysgalactiae subsp. equisimilis GGS_124 branched-chain amino acid aminotransferase YP_002996880.1 1121813 R 486410 CDS YP_002996881.1 251782578 8112366 1123037..1124047 1 NC_012891.1 similar to transposase [Streptococcus pyogenes MGAS10394]; transposase 1124047 8112366 SDEG_1171 Streptococcus dysgalactiae subsp. equisimilis GGS_124 transposase YP_002996881.1 1123037 D 486410 CDS YP_002996882.1 251782579 8111521 complement(1124044..1126503) 1 NC_012891.1 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling; DNA topoisomerase IV subunit A 1126503 parC 8111521 parC Streptococcus dysgalactiae subsp. equisimilis GGS_124 DNA topoisomerase IV subunit A YP_002996882.1 1124044 R 486410 CDS YP_002996883.1 251782580 8111751 complement(1126700..1127518) 1 NC_012891.1 similar to hypothetical protein MGAS10270 Spy0770 [Streptococcus pyogenes MGAS10270]; hypothetical protein 1127518 8111751 SDEG_1173 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996883.1 1126700 R 486410 CDS YP_002996884.1 251782581 8111522 complement(1127585..1129537) 1 NC_012891.1 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling; DNA topoisomerase IV subunit B 1129537 parE 8111522 parE Streptococcus dysgalactiae subsp. equisimilis GGS_124 DNA topoisomerase IV subunit B YP_002996884.1 1127585 R 486410 CDS YP_002996885.1 251782582 8111752 1129669..1130310 1 NC_012891.1 involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsX; glycerol-3-phosphate acyltransferase PlsY 1130310 8111752 SDEG_1175 Streptococcus dysgalactiae subsp. equisimilis GGS_124 glycerol-3-phosphate acyltransferase PlsY YP_002996885.1 1129669 D 486410 CDS YP_002996886.1 251782583 8111523 complement(1130370..1131641) 1 NC_012891.1 catalyzes the formation of N-carbamoyl-L-aspartate from (S)-dihydroorotate in pyrimidine biosynthesis; dihydroorotase 1131641 pyrC 8111523 pyrC Streptococcus dysgalactiae subsp. equisimilis GGS_124 dihydroorotase YP_002996886.1 1130370 R 486410 CDS YP_002996887.1 251782584 8111339 complement(1131773..1132426) 1 NC_012891.1 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine; uracil-DNA glycosylase 1132426 ung 8111339 ung Streptococcus dysgalactiae subsp. equisimilis GGS_124 uracil-DNA glycosylase YP_002996887.1 1131773 R 486410 CDS YP_002996888.1 251782585 8111942 complement(1132559..1133209) 1 NC_012891.1 similar to cystine transport system permease protein [Streptococcus pyogenes MGAS5005]; cystine transport system permease 1133209 8111942 SDEG_1178 Streptococcus dysgalactiae subsp. equisimilis GGS_124 cystine transport system permease YP_002996888.1 1132559 R 486410 CDS YP_002996889.1 251782586 8111524 complement(1133238..1134137) 1 NC_012891.1 similar to cystine-binding protein [Streptococcus pyogenes MGAS10394]; cystine-binding protein 1134137 8111524 SDEG_1179 Streptococcus dysgalactiae subsp. equisimilis GGS_124 cystine-binding protein YP_002996889.1 1133238 R 486410 CDS YP_002996890.1 251782587 8111525 complement(1134219..1135673) 1 NC_012891.1 catalyzes the hydrolysis of a monocarboxylic acid amid to form a monocarboxylate and ammonia; amidase 1135673 amiC 8111525 amiC Streptococcus dysgalactiae subsp. equisimilis GGS_124 amidase YP_002996890.1 1134219 R 486410 CDS YP_002996891.1 251782588 8112321 complement(1135852..1136649) 1 NC_012891.1 similar to transposase IS861 orfB [Streptococcus equi subsp. zooepidemicus MGCS10565]; transposase IS861 orfB 1136649 8112321 SDEG_1181 Streptococcus dysgalactiae subsp. equisimilis GGS_124 transposase IS861 orfB YP_002996891.1 1135852 R 486410 CDS YP_002996892.1 251782589 8111526 complement(1136685..1137215) 1 NC_012891.1 similar to transposase IS861 orfA [Streptococcus equi subsp. zooepidemicus MGCS10565]; transposase IS861 orfA 1137215 8111526 SDEG_1182 Streptococcus dysgalactiae subsp. equisimilis GGS_124 transposase IS861 orfA YP_002996892.1 1136685 R 486410 CDS YP_002996893.1 251782590 8111527 complement(1137270..1138016) 1 NC_012891.1 similar to acetyltransferase GNAT family [Streptococcus equi subsp. zooepidemicus MGCS10565]; GNAT family acetyltransferase 1138016 8111527 SDEG_1183 Streptococcus dysgalactiae subsp. equisimilis GGS_124 GNAT family acetyltransferase YP_002996893.1 1137270 R 486410 CDS YP_002996894.1 251782591 8111528 complement(1138057..1138686) 1 NC_012891.1 similar to Orotate phosphoribosyltransferase [Streptococcus thermophilus LMD-9]; orotate phosphoribosyl transferase 1138686 pyrE 8111528 pyrE Streptococcus dysgalactiae subsp. equisimilis GGS_124 orotate phosphoribosyl transferase YP_002996894.1 1138057 R 486410 CDS YP_002996895.1 251782592 8111341 complement(1138747..1139439) 1 NC_012891.1 type 1 subfamily; involved in last step of pyrimidine biosynthesis; converts orotidine 5'-phosphate to UMP and carbon dioxide; OMP decarboxylase; OMPDCase; OMPdecase; orotidine 5'-phosphate decarboxylase 1139439 pyrF 8111341 pyrF Streptococcus dysgalactiae subsp. equisimilis GGS_124 orotidine 5'-phosphate decarboxylase YP_002996895.1 1138747 R 486410 CDS YP_002996896.1 251782593 8111342 complement(1139651..1140199) 1 NC_012891.1 similar to hypothetical protein M5005 Spy 0702 [Streptococcus pyogenes MGAS5005]; hypothetical protein 1140199 8111342 SDEG_1186 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996896.1 1139651 R 486410 CDS YP_002996897.1 251782594 8111529 1140423..1141340 1 NC_012891.1 similar to transcriptional regulators LysR family [Streptococcus pyogenes MGAS2096]; LysR family transcriptional regulator 1141340 cpsY 8111529 cpsY Streptococcus dysgalactiae subsp. equisimilis GGS_124 LysR family transcriptional regulator YP_002996897.1 1140423 D 486410 CDS YP_002996898.1 251782595 8111649 complement(1141422..1142198) 1 NC_012891.1 similar to attenuator of transcription LytR family regulator [Streptococcus pyogenes MGAS6180]; attenuator of transcription, LytR family regulator 1142198 cpsX 8111649 cpsX Streptococcus dysgalactiae subsp. equisimilis GGS_124 attenuator of transcription, LytR family regulator YP_002996898.1 1141422 R 486410 CDS YP_002996899.1 251782596 8111648 complement(1142185..1142898) 1 NC_012891.1 catalyzes the reversible phosphorolysis of ribonucleosides and 2'- deoxyribonucleosides to the free base and (2'-deoxy)ribose-1- phosphate; purine nucleoside phosphorylase 1142898 deoD 8111648 deoD Streptococcus dysgalactiae subsp. equisimilis GGS_124 purine nucleoside phosphorylase YP_002996899.1 1142185 R 486410 CDS YP_002996900.1 251782597 8111669 complement(1143451..1144260) 1 NC_012891.1 catalyzes the formation of a purine and ribose phosphate from a purine nucleoside; in E. coli this enzyme functions in xanthosine degradation; purine nucleoside phosphorylase 1144260 punA 8111669 punA Streptococcus dysgalactiae subsp. equisimilis GGS_124 purine nucleoside phosphorylase YP_002996900.1 1143451 R 486410 CDS YP_002996901.1 251782598 8111329 complement(1144244..1144690) 1 NC_012891.1 similar to arsenate reductase [Streptococcus pyogenes MGAS10750]; arsenate reductase 1144690 arsC 8111329 arsC Streptococcus dysgalactiae subsp. equisimilis GGS_124 arsenate reductase YP_002996901.1 1144244 R 486410 CDS YP_002996902.1 251782599 8112344 complement(1144703..1145914) 1 NC_012891.1 catalyzes the transfer of phosphate between the C1 and C5 carbons of pentose; phosphopentomutase 1145914 deoB 8112344 deoB Streptococcus dysgalactiae subsp. equisimilis GGS_124 phosphopentomutase YP_002996902.1 1144703 R 486410 CDS YP_002996903.1 251782600 8111667 complement(1145993..1146676) 1 NC_012891.1 Catalyzes D-ribose 5-phosphate --> D-ribulose 5-phosphate in the nonoxidative branch of the pentose phosphate pathway; ribose-5-phosphate isomerase A 1146676 rpiA 8111667 rpiA Streptococcus dysgalactiae subsp. equisimilis GGS_124 ribose-5-phosphate isomerase A YP_002996903.1 1145993 R 486410 CDS YP_002996904.1 251782601 8111057 1146818..1148194 1 NC_012891.1 in Escherichia coli this protein is involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2-thiouridine, which is found in the wobble position of some tRNAs and affects ribosomal frameshifting; shows potassium-dependent dimerization and GTP hydrolysis; also involved in regulation of glutamate-dependent acid resistance and activation of gadE; tRNA modification GTPase TrmE 1148194 trmE 8111057 trmE Streptococcus dysgalactiae subsp. equisimilis GGS_124 tRNA modification GTPase TrmE YP_002996904.1 1146818 D 486410 CDS YP_002996905.1 251782602 8111927 complement(1148262..1149671) 1 NC_012891.1 divalent metal ion-dependent extracellular dipeptidase; able to hydrolyze a broad range of dipeptides but no tri-, tetra-, or larger oligopeptides; differences in the amino acid specificity of the cleavage site varies between species; similar to succinyl-diaminopimelate desuccinylases; dipeptidase PepV 1149671 8111927 SDEG_1195 Streptococcus dysgalactiae subsp. equisimilis GGS_124 dipeptidase PepV YP_002996905.1 1148262 R 486410 CDS YP_002996906.1 251782603 8111530 complement(1149849..1150451) 1 NC_012891.1 similar to NAD(P)H-dependent quinone reductase [Streptococcus pyogenes MGAS6180]; NAD(P)H-dependent quinone reductase 1150451 8111530 SDEG_1196 Streptococcus dysgalactiae subsp. equisimilis GGS_124 NAD(P)H-dependent quinone reductase YP_002996906.1 1149849 R 486410 CDS YP_002996907.1 251782604 8111531 1150764..1151108 1 NC_012891.1 similar to pyruvate oxidase or other thiamine pyrophosphate-requiring enzyme [Lactobacillus casei ATCC 334]; pyruvate oxidase or other thiamine pyrophosphate-requiring enzyme 1151108 8111531 SDEG_1197 Streptococcus dysgalactiae subsp. equisimilis GGS_124 pyruvate oxidase or other thiamine pyrophosphate-requiring enzyme YP_002996907.1 1150764 D 486410 CDS YP_002996908.1 251782605 8111532 1150933..1151835 1 NC_012891.1 probable ORF of N-terminal portion of pyruvate oxidase [Lactobacillus paracasei] resulted from mutation by unknown reason; pyruvate oxidase 1151835 8111532 SDEG_1198 Streptococcus dysgalactiae subsp. equisimilis GGS_124 pyruvate oxidase YP_002996908.1 1150933 D 486410 CDS YP_002996909.1 251782606 8111533 1152006..1152422 1 NC_012891.1 probable ORF of C-terminal portion of pyruvate oxidase [Lactobacillus paracasei] resulted from mutation by unknown reason; pyruvate oxidase 1152422 8111533 SDEG_1199 Streptococcus dysgalactiae subsp. equisimilis GGS_124 pyruvate oxidase YP_002996909.1 1152006 D 486410 CDS YP_002996910.1 251782607 8111534 complement(1152475..1154259) 1 NC_012891.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision; excinuclease ABC subunit C 1154259 uvrC 8111534 uvrC Streptococcus dysgalactiae subsp. equisimilis GGS_124 excinuclease ABC subunit C YP_002996910.1 1152475 R 486410 CDS YP_002996911.1 251782608 8111946 complement(1154389..1154538) 1 NC_012891.1 similar to phosphatase YbjI [Escherichia coli HS]; phosphatase 1154538 ybjI 8111946 ybjI Streptococcus dysgalactiae subsp. equisimilis GGS_124 phosphatase YP_002996911.1 1154389 R 486410 CDS YP_002996912.1 251782609 8111959 complement(1154594..1155973) 1 NC_012891.1 similar to succinate-semialdehyde dehydrogenase [NADP+] [Streptococcus pyogenes MGAS10394]; succinate-semialdehyde dehydrogenase 1155973 gabD 8111959 gabD Streptococcus dysgalactiae subsp. equisimilis GGS_124 succinate-semialdehyde dehydrogenase YP_002996912.1 1154594 R 486410 CDS YP_002996913.1 251782610 8111982 complement(1156047..1156754) 1 NC_012891.1 similar to hydrolase HAD superfamily [Streptococcus pyogenes MGAS5005]; HAD superfamily hydrolase 1156754 8111982 SDEG_1203 Streptococcus dysgalactiae subsp. equisimilis GGS_124 HAD superfamily hydrolase YP_002996913.1 1156047 R 486410 CDS YP_002996914.1 251782611 8111535 1156924..1157244 1 NC_012891.1 similar to hypothetical protein RUMTOR 00521 [Ruminococcus torques ATCC 27756]; hypothetical protein 1157244 8111535 SDEG_1204 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996914.1 1156924 D 486410 CDS YP_002996915.1 251782612 8111536 1157306..1158301 1 NC_012891.1 similar to permease [Campylobacter hominis ATCC BAA-381]; permease 1158301 8111536 SDEG_1205 Streptococcus dysgalactiae subsp. equisimilis GGS_124 permease YP_002996915.1 1157306 D 486410 CDS YP_002996916.1 251782613 8111537 1158314..1158568 1 NC_012891.1 similar to hypothetical protein CLORAM 03030 [Clostridium ramosum DSM 1402]; hypothetical protein 1158568 8111537 SDEG_1206 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996916.1 1158314 D 486410 CDS YP_002996917.1 251782614 8111539 complement(1159571..1160077) 1 NC_012891.1 similar to hypothetical protein SGO 0826 [Streptococcus gordonii str. Challis substr. CH1]; hypothetical protein 1160077 8111539 SDEG_1208 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996917.1 1159571 R 486410 CDS YP_002996918.1 251782615 8111540 complement(1160173..1161222) 1 NC_012891.1 similar to iron(III)-binding protein [Streptococcus pyogenes MGAS6180]; iron(III)-binding protein 1161222 8111540 SDEG_1209 Streptococcus dysgalactiae subsp. equisimilis GGS_124 iron(III)-binding protein YP_002996918.1 1160173 R 486410 CDS YP_002996919.1 251782616 8111541 complement(1161209..1162003) 1 NC_012891.1 similar to two-component response regulator YesN [Streptococcus pyogenes MGAS10394]; two-component response regulator YesN 1162003 yesN 8111541 yesN Streptococcus dysgalactiae subsp. equisimilis GGS_124 two-component response regulator YesN YP_002996919.1 1161209 R 486410 CDS YP_002996920.1 251782617 8111963 complement(1162007..1163656) 1 NC_012891.1 similar to two-component sensor kinase YesM [Streptococcus pyogenes MGAS10394]; two-component sensor kinase YesM 1163656 yesM 8111963 yesM Streptococcus dysgalactiae subsp. equisimilis GGS_124 two-component sensor kinase YesM YP_002996920.1 1162007 R 486410 CDS YP_002996921.1 251782618 8111960 complement(1163802..1164629) 1 NC_012891.1 similar to PTS system mannose/fructose family IID component [Streptococcus pyogenes MGAS6180]; PTS system mannose/fructose family transporter subunit IID 1164629 ptsD 8111960 ptsD Streptococcus dysgalactiae subsp. equisimilis GGS_124 PTS system mannose/fructose family transporter subunit IID YP_002996921.1 1163802 R 486410 CDS YP_002996922.1 251782619 8111325 complement(1164626..1165435) 1 NC_012891.1 similar to PTS system mannose/fructose family IIC component [Streptococcus pyogenes MGAS2096]; PTS system mannose/fructose family transporter subunit IIC 1165435 ptsC 8111325 ptsC Streptococcus dysgalactiae subsp. equisimilis GGS_124 PTS system mannose/fructose family transporter subunit IIC YP_002996922.1 1164626 R 486410 CDS YP_002996923.1 251782620 8111324 complement(1165451..1165942) 1 NC_012891.1 similar to PTS system mannose/fructose family IIB component [Streptococcus pyogenes MGAS10750]; PTS system mannose/fructose family transporter subunit IIB 1165942 ptsB 8111324 ptsB Streptococcus dysgalactiae subsp. equisimilis GGS_124 PTS system mannose/fructose family transporter subunit IIB YP_002996923.1 1165451 R 486410 CDS YP_002996924.1 251782621 8111323 complement(1165961..1166386) 1 NC_012891.1 similar to PTS system mannose/fructose family IIA component [Streptococcus pyogenes MGAS2096]; PTS system mannose/fructose family transporter subunit IIA 1166386 8111323 SDEG_1215 Streptococcus dysgalactiae subsp. equisimilis GGS_124 PTS system mannose/fructose family transporter subunit IIA YP_002996924.1 1165961 R 486410 CDS YP_002996925.1 251782622 8111542 complement(1166593..1167612) 1 NC_012891.1 similar to hypothetical membrane spanning protein [Streptococcus pyogenes MGAS10394]; hypothetical protein 1167612 8111542 SDEG_1216 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996925.1 1166593 R 486410 CDS YP_002996926.1 251782623 8111543 complement(1167723..1168892) 1 NC_012891.1 similar to hypothetical protein STRINF 01596 [Streptococcus infantarius subsp. infantarius ATCC BAA-102]; hypothetical protein 1168892 8111543 SDEG_1217 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996926.1 1167723 R 486410 CDS YP_002996927.1 251782624 8111544 complement(1169082..1169378) 1 NC_012891.1 similar to SpiA (OrfY protein) ( sakacin P immunity protein) [Lactobacillus casei BL23]; sakacin P immunityprotein 1169378 spiA 8111544 spiA Streptococcus dysgalactiae subsp. equisimilis GGS_124 sakacin P immunityprotein YP_002996927.1 1169082 R 486410 CDS YP_002996928.1 251782625 8110498 complement(1169378..1169656) 1 NC_012891.1 similar to hypothetical protein STRINF 01005 [Streptococcus infantarius subsp. infantarius ATCC BAA-102]; hypothetical protein 1169656 8110498 SDEG_1219 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996928.1 1169378 R 486410 CDS YP_002996929.1 251782626 8111545 complement(1169816..1170466) 1 NC_012891.1 similar to hypothetical protein STRINF 01223 [Streptococcus infantarius subsp. infantarius ATCC BAA-102]; hypothetical protein 1170466 8111545 SDEG_1220 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996929.1 1169816 R 486410 CDS YP_002996930.1 251782627 8111546 complement(1170479..1170916) 1 NC_012891.1 this stereospecific enzymes reduces the R isomer of methionine sulfoxide while MsrA reduces the S form; provides protection against oxidative stress; methionine sulfoxide reductase B 1170916 msrB 8111546 msrB Streptococcus dysgalactiae subsp. equisimilis GGS_124 methionine sulfoxide reductase B YP_002996930.1 1170479 R 486410 CDS YP_002996931.1 251782628 8110946 complement(1171092..1172924) 1 NC_012891.1 binds to the ribosome on the universally-conserved alpha-sarcin loop; GTP-binding protein LepA 1172924 lepA 8110946 lepA Streptococcus dysgalactiae subsp. equisimilis GGS_124 GTP-binding protein LepA YP_002996931.1 1171092 R 486410 CDS YP_002996932.1 251782629 8110892 complement(1172994..1173452) 1 NC_012891.1 catalyzes the formation of nucleoside triphosphate from ATP and nucleoside diphosphate; nucleoside diphosphate kinase 1173452 ndk 8110892 ndk Streptococcus dysgalactiae subsp. equisimilis GGS_124 nucleoside diphosphate kinase YP_002996932.1 1172994 R 486410 CDS YP_002996933.1 251782630 8111709 1173530..1173742 1 NC_012891.1 similar to hypothetical protein SAM 0929 [Streptococcus agalactiae CJB111]; hypothetical protein 1173742 8111709 SDEG_1224 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996933.1 1173530 D 486410 CDS YP_002996934.1 251782631 8111547 1173618..1173821 1 NC_012891.1 similar to hypothetical protein SAM 0929 [Streptococcus agalactiae CJB111]; hypothetical protein 1173821 8111547 SDEG_1225 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996934.1 1173618 D 486410 CDS YP_002996935.1 251782632 8111548 1173947..1174408 1 NC_012891.1 similar to conserved hypothetical protein [Streptococcus agalactiae 18RS21]; hypothetical protein 1174408 8111548 SDEG_1226 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996935.1 1173947 D 486410 CDS YP_002996936.1 251782633 8111549 1174478..1174750 1 NC_012891.1 similar to conserved hypothetical protein [Streptococcus agalactiae H36B]; hypothetical protein 1174750 8111549 SDEG_1227 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996936.1 1174478 D 486410 CDS YP_002996937.1 251782634 8111550 complement(1174896..1175624) 1 NC_012891.1 similar to hypothetical protein MGAS2096 Spy0846 [Streptococcus pyogenes MGAS2096]; hypothetical protein 1175624 8111550 SDEG_1228 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996937.1 1174896 R 486410 CDS YP_002996938.1 251782635 8111551 complement(1175548..1175889) 1 NC_012891.1 similar to hypothetical protein SPs1174 [Streptococcus pyogenes SSI-1]; hypothetical protein 1175889 8111551 SDEG_1229 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996938.1 1175548 R 486410 CDS YP_002996939.1 251782636 8111552 complement(1175886..1176755) 1 NC_012891.1 similar to hypothetical cytosolic protein [Streptococcus pyogenes MGAS5005]; hypothetical protein 1176755 8111552 SDEG_1230 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996939.1 1175886 R 486410 CDS YP_002996940.1 251782637 8111553 complement(1176755..1180870) 1 NC_012891.1 similar to hypothetical cytosolic protein [Streptococcus pyogenes MGAS10750]; hypothetical protein 1180870 8111553 SDEG_1231 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996940.1 1176755 R 486410 CDS YP_002996941.1 251782638 8111554 complement(1180894..1181010) 1 NC_012891.1 similar to hypothetical protein MGAS9429 Spy0884 [Streptococcus pyogenes MGAS9429]; hypothetical protein 1181010 8111554 SDEG_1232 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996941.1 1180894 R 486410 CDS YP_002996942.1 251782639 8111555 complement(1181346..1181987) 1 NC_012891.1 similar to hypothetical membrane spanning protein [Streptococcus pyogenes MGAS10270]; hypothetical protein 1181987 8111555 SDEG_1233 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996942.1 1181346 R 486410 CDS YP_002996943.1 251782640 8111556 complement(1181975..1182739) 1 NC_012891.1 similar to haloacid dehalogenase-like hydrolase [Streptococcus pyogenes MGAS2096]; haloacid dehalogenase-like hydrolase 1182739 8111556 SDEG_1234 Streptococcus dysgalactiae subsp. equisimilis GGS_124 haloacid dehalogenase-like hydrolase YP_002996943.1 1181975 R 486410 CDS YP_002996944.1 251782641 8111557 complement(1182739..1183491) 1 NC_012891.1 similar to acyl-acyl carrier protein thioesterase [Streptococcus pyogenes MGAS5005]; acyl-acyl carrier protein thioesterase 1183491 8111557 SDEG_1235 Streptococcus dysgalactiae subsp. equisimilis GGS_124 acyl-acyl carrier protein thioesterase YP_002996944.1 1182739 R 486410 CDS YP_002996945.1 251782642 8111558 complement(1183501..1184631) 1 NC_012891.1 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III; coproporphyrinogen III oxidase 1184631 hemN 8111558 hemN Streptococcus dysgalactiae subsp. equisimilis GGS_124 coproporphyrinogen III oxidase YP_002996945.1 1183501 R 486410 CDS YP_002996946.1 251782643 8112029 complement(1184693..1185334) 1 NC_012891.1 similar to hypothetical protein SpyM50995 [Streptococcus pyogenes str. Manfredo]; hypothetical protein 1185334 8112029 SDEG_1237 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996946.1 1184693 R 486410 CDS YP_002996947.1 251782644 8111559 complement(1185458..1186813) 1 NC_012891.1 catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; phosphoglucosamine mutase 1186813 glmM 8111559 glmM Streptococcus dysgalactiae subsp. equisimilis GGS_124 phosphoglucosamine mutase YP_002996947.1 1185458 R 486410 CDS YP_002996948.1 251782645 8111886 complement(1186867..1187823) 1 NC_012891.1 similar to hypothetical membrane associated protein [Streptococcus pyogenes MGAS6180]; hypothetical protein 1187823 8111886 SDEG_1239 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996948.1 1186867 R 486410 CDS YP_002996949.1 251782646 8111560 complement(1187820..1188671) 1 NC_012891.1 similar to hypothetical protein SpyM50998 [Streptococcus pyogenes str. Manfredo]; hypothetical protein 1188671 8111560 SDEG_1240 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996949.1 1187820 R 486410 CDS YP_002996950.1 251782647 8111561 1188775..1190118 1 NC_012891.1 similar to UDP-N-acetylmuramoylalanyl-D-glutamate- 2,6-diaminopimelate ligase [Streptococcus pyogenes MGAS10270]; UDP-N-acetylmuramoylalanyl-D-glutamate-2,6- diaminopimelate ligase 1190118 8111561 SDEG_1241 Streptococcus dysgalactiae subsp. equisimilis GGS_124 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6- diaminopimelate ligase YP_002996950.1 1188775 D 486410 CDS YP_002996951.1 251782648 8111562 1190118..1190909 1 NC_012891.1 similar to CobB/CobQ-like glutamine amidotransferase domain [Streptococcus pyogenes MGAS2096]; CobB/CobQ-like glutamine amidotransferase domain 1190909 8111562 SDEG_1242 Streptococcus dysgalactiae subsp. equisimilis GGS_124 CobB/CobQ-like glutamine amidotransferase domain YP_002996951.1 1190118 D 486410 CDS YP_002996952.1 251782649 8111563 complement(1191014..1192003) 1 NC_012891.1 similar to lipoate-protein ligase [Streptococcus pyogenes M1 GAS]; lipoate-protein ligase 1192003 lplB 8111563 lplB Streptococcus dysgalactiae subsp. equisimilis GGS_124 lipoate-protein ligase YP_002996952.1 1191014 R 486410 CDS YP_002996953.1 251782650 8110907 complement(1192086..1193249) 1 NC_012891.1 similar to hypothetical membrane associated protein [Streptococcus equi subsp. zooepidemicus MGCS10565]; hypothetical protein 1193249 8110907 SDEG_1244 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996953.1 1192086 R 486410 CDS YP_002996954.1 251782651 8111564 complement(1193195..1193509) 1 NC_012891.1 similar to transcriptional regulator PadR family [Streptococcus pyogenes MGAS10394]; PadR family transcriptional regulator 1193509 8111564 SDEG_1245 Streptococcus dysgalactiae subsp. equisimilis GGS_124 PadR family transcriptional regulator YP_002996954.1 1193195 R 486410 CDS YP_002996955.1 251782652 8111565 complement(1193739..1195502) 1 NC_012891.1 similar to dihydrolipoamide dehydrogenase [Streptococcus pyogenes MGAS10394]; dihydrolipoamide dehydrogenase 1195502 acoL 8111565 acoL Streptococcus dysgalactiae subsp. equisimilis GGS_124 dihydrolipoamide dehydrogenase YP_002996955.1 1193739 R 486410 CDS YP_002996956.1 251782653 8112302 1195535..1195774 1 NC_012891.1 similar to hypothetical protein MGAS2096 Spy0827 [Streptococcus pyogenes MGAS2096]; hypothetical protein 1195774 8112302 SDEG_1247 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996956.1 1195535 D 486410 CDS YP_002996957.1 251782654 8111566 complement(1195829..1197238) 1 NC_012891.1 similar to dihydrolipoamide acetyltransferase [Streptococcus pyogenes MGAS10394]; branched-chain alpha-keto acid dehydrogenase E2 subunit 1197238 acoC 8111566 acoC Streptococcus dysgalactiae subsp. equisimilis GGS_124 branched-chain alpha-keto acid dehydrogenase E2 subunit YP_002996957.1 1195829 R 486410 CDS YP_002996958.1 251782655 8112301 complement(1197418..1198419) 1 NC_012891.1 similar to pyruvate dehydrogenase E1 component beta subunit [Streptococcus pyogenes MGAS10394]; pyruvate dehydrogenase E1 component subunit beta 1198419 acoB 8112301 acoB Streptococcus dysgalactiae subsp. equisimilis GGS_124 pyruvate dehydrogenase E1 component subunit beta YP_002996958.1 1197418 R 486410 CDS YP_002996959.1 251782656 8112300 complement(1198475..1199455) 1 NC_012891.1 similar to pyruvate dehydrogenase E1 component alpha subunit [Streptococcus pyogenes MGAS10394]; pyruvate dehydrogenase E1 component subunit alpha 1199455 acoA 8112300 acoA Streptococcus dysgalactiae subsp. equisimilis GGS_124 pyruvate dehydrogenase E1 component subunit alpha YP_002996959.1 1198475 R 486410 CDS YP_002996960.1 251782657 8112299 complement(1199728..1201635) 1 NC_012891.1 similar to ABC transporter ATP-binding protein [Streptococcus pyogenes MGAS5005]; ABC transporter ATP-binding protein 1201635 8112299 SDEG_1251 Streptococcus dysgalactiae subsp. equisimilis GGS_124 ABC transporter ATP-binding protein YP_002996960.1 1199728 R 486410 CDS YP_002996961.1 251782658 8111567 complement(1201714..1202007) 1 NC_012891.1 similar to hypothetical protein SpyoM01000868 [Streptococcus pyogenes M49 591]; hypothetical protein 1202007 8111567 SDEG_1252 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996961.1 1201714 R 486410 CDS YP_002996962.1 251782659 8111568 complement(1202037..1202822) 1 NC_012891.1 similar to acetyl esterase [Streptococcus pyogenes MGAS6180]; acetyl esterase 1202822 estA 8111568 estA Streptococcus dysgalactiae subsp. equisimilis GGS_124 acetyl esterase YP_002996962.1 1202037 R 486410 CDS YP_002996963.1 251782660 8111873 complement(1202955..1204616) 1 NC_012891.1 similar to Zn-dependent hydrolase [Streptococcus pyogenes MGAS10394]; Zn-dependent hydrolase 1204616 8111873 SDEG_1254 Streptococcus dysgalactiae subsp. equisimilis GGS_124 Zn-dependent hydrolase YP_002996963.1 1202955 R 486410 CDS YP_002996964.1 251782661 8111569 complement(1204828..1205586) 1 NC_012891.1 similar to ABC transporter ATP-binding protein [Streptococcus pyogenes MGAS10394]; ABC transporter ATP-binding protein 1205586 8111569 SDEG_1255 Streptococcus dysgalactiae subsp. equisimilis GGS_124 ABC transporter ATP-binding protein YP_002996964.1 1204828 R 486410 CDS YP_002996965.1 251782662 8111570 complement(1205583..1206452) 1 NC_012891.1 similar to ABC transporter permease protein [Streptococcus pyogenes str. Manfredo]; ABC transporter permease 1206452 8111570 SDEG_1256 Streptococcus dysgalactiae subsp. equisimilis GGS_124 ABC transporter permease YP_002996965.1 1205583 R 486410 CDS YP_002996966.1 251782663 8111571 complement(1206470..1207465) 1 NC_012891.1 similar to ABC transporter substrate-binding protein [Streptococcus pyogenes MGAS10394]; ABC transporter substrate-binding protein 1207465 8111571 SDEG_1257 Streptococcus dysgalactiae subsp. equisimilis GGS_124 ABC transporter substrate-binding protein YP_002996966.1 1206470 R 486410 CDS YP_002996967.1 251782664 8111572 complement(1207928..1209205) 1 NC_012891.1 similar to hypothetical protein gbs1118 [Streptococcus agalactiae NEM316]; hypothetical protein 1209205 8111572 SDEG_1258 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996967.1 1207928 R 486410 CDS YP_002996968.1 251782665 8111573 complement(1211214..1211951) 1 NC_012891.1 Class B; non-specific; catalyzes the dephosphorylation of organic phosphomonoesters; also has phosphotransferase activity; acid phosphatase/phosphotransferase 1211951 aphA 8111573 aphA Streptococcus dysgalactiae subsp. equisimilis GGS_124 acid phosphatase/phosphotransferase YP_002996968.1 1211214 R 486410 CDS YP_002996969.1 251782666 8111574 complement(1212071..1212292) 1 NC_012891.1 similar to hypothetical protein SAG0634 [Streptococcus agalactiae 2603V/R]; hypothetical protein 1212292 8111574 SDEG_1260 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996969.1 1212071 R 486410 CDS YP_002996970.1 251782667 8111575 1212461..1212751 1 NC_012891.1 similar to ISSag4 transposase orfA [Streptococcus agalactiae A909]; ISSag4, transposase orfA 1212751 8111575 SDEG_1261 Streptococcus dysgalactiae subsp. equisimilis GGS_124 ISSag4, transposase orfA YP_002996970.1 1212461 D 486410 CDS YP_002996971.1 251782668 8111576 complement(1213155..1213496) 1 NC_012891.1 similar to hypothetical protein gbs1153 [Streptococcus agalactiae NEM316]; hypothetical protein 1213496 8111576 SDEG_1262 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996971.1 1213155 R 486410 CDS YP_002996972.1 251782669 8111577 1213632..1215326 1 NC_012891.1 similar to fibronectin-binding protein [Streptococcus pyogenes MGAS10270]; fibronectin-binding protein 1215326 fbp 8111577 fbp Streptococcus dysgalactiae subsp. equisimilis GGS_124 fibronectin-binding protein YP_002996972.1 1213632 D 486410 CDS YP_002996973.1 251782670 8111885 complement(1215389..1216654) 1 NC_012891.1 similar to tetratricopeptide repeat family protein [Streptococcus pyogenes MGAS10394]; hypothetical protein 1216654 8111885 SDEG_1264 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996973.1 1215389 R 486410 CDS YP_002996974.1 251782671 8111578 complement(1216626..1217807) 1 NC_012891.1 similar to hypothetical membrane spanning protein [Streptococcus pyogenes MGAS5005]; hypothetical protein 1217807 8111578 SDEG_1265 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996974.1 1216626 R 486410 CDS YP_002996975.1 251782672 8111579 complement(1217856..1218335) 1 NC_012891.1 similar to 7,8-dihydro-8-oxoguanine-triphosphatase [Streptococcus pyogenes MGAS10750]; 7,8-dihydro-8-oxoguanine-triphosphatase 1218335 8111579 SDEG_1266 Streptococcus dysgalactiae subsp. equisimilis GGS_124 7,8-dihydro-8-oxoguanine-triphosphatase YP_002996975.1 1217856 R 486410 CDS YP_002996976.1 251782673 8111580 1218531..1218722 1 NC_012891.1 similar to hypothetical protein STER 0685 [Streptococcus thermophilus LMD-9]; hypothetical protein 1218722 8111580 SDEG_1267 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996976.1 1218531 D 486410 CDS YP_002996977.1 251782674 8111581 complement(1218810..1219244) 1 NC_012891.1 similar to hypothetical protein CLORAM 02318 [Clostridium ramosum DSM 1402]; hypothetical protein 1219244 8111581 SDEG_1268 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996977.1 1218810 R 486410 CDS YP_002996978.1 251782675 8111582 complement(1219695..1220747) 1 NC_012891.1 similar to dTDP-glucose 4,6-dehydratase [Streptococcus pyogenes MGAS10394]; dTDP-glucose 4,6-dehydratase 1220747 cpsFQ 8111582 cpsFQ Streptococcus dysgalactiae subsp. equisimilis GGS_124 dTDP-glucose 4,6-dehydratase YP_002996978.1 1219695 R 486410 CDS YP_002996979.1 251782676 8111647 complement(1220982..1221575) 1 NC_012891.1 similar to dTDP-4-dehydrorhamnose 3,5-epimerase [Streptococcus pyogenes MGAS6180]; dTDP-4-dehydrorhamnose 3,5-epimerase 1221575 cpsFP 8111647 cpsFP Streptococcus dysgalactiae subsp. equisimilis GGS_124 dTDP-4-dehydrorhamnose 3,5-epimerase YP_002996979.1 1220982 R 486410 CDS YP_002996980.1 251782677 8111646 complement(1221575..1222444) 1 NC_012891.1 similar to glucose-1-phosphate thymidyl transferase [Streptococcus pyogenes str. Manfredo]; glucose-1-phosphate thymidylyltransferase 1222444 cpsFO 8111646 cpsFO Streptococcus dysgalactiae subsp. equisimilis GGS_124 glucose-1-phosphate thymidylyltransferase YP_002996980.1 1221575 R 486410 CDS YP_002996981.1 251782678 8111645 complement(1222502..1223608) 1 NC_012891.1 similar to glycine/D-amino acid oxidases family [Streptococcus pyogenes MGAS10750]; glycine/D-amino acid oxidase 1223608 8111645 SDEG_1272 Streptococcus dysgalactiae subsp. equisimilis GGS_124 glycine/D-amino acid oxidase YP_002996981.1 1222502 R 486410 CDS YP_002996982.1 251782679 8111583 complement(1223618..1224439) 1 NC_012891.1 similar to hypothetical protein STRINF 01350 [Streptococcus infantarius subsp. infantarius ATCC BAA-102]; hypothetical protein 1224439 8111583 SDEG_1273 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996982.1 1223618 R 486410 CDS YP_002996983.1 251782680 8111584 complement(1224457..1225245) 1 NC_012891.1 similar to NIF3 (NGG1p interacting factor 3) family protein [Streptococcus pyogenes str. Manfredo]; NIF3 (NGG1p interacting factor 3) family protein 1225245 8111584 SDEG_1274 Streptococcus dysgalactiae subsp. equisimilis GGS_124 NIF3 (NGG1p interacting factor 3) family protein YP_002996983.1 1224457 R 486410 CDS YP_002996984.1 251782681 8111585 complement(1225235..1225921) 1 NC_012891.1 similar to hypothetical cytosolic protein [Streptococcus pyogenes MGAS2096]; hypothetical protein 1225921 8111585 SDEG_1275 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996984.1 1225235 R 486410 CDS YP_002996985.1 251782682 8111586 complement(1226002..1226670) 1 NC_012891.1 similar to endonuclease III [Streptococcus pyogenes MGAS5005]; endonuclease III 1226670 nth 8111586 nth Streptococcus dysgalactiae subsp. equisimilis GGS_124 endonuclease III YP_002996985.1 1226002 R 486410 CDS YP_002996986.1 251782683 8111724 complement(1226655..1227338) 1 NC_012891.1 similar to DNA replication protein [Streptococcus pyogenes MGAS10394]; DNA replication protein 1227338 dnaD 8111724 dnaD Streptococcus dysgalactiae subsp. equisimilis GGS_124 DNA replication protein YP_002996986.1 1226655 R 486410 CDS YP_002996987.1 251782684 8111844 complement(1227556..1228074) 1 NC_012891.1 catalyzes a salvage reaction resulting in the formation of AMP which is metabolically less costly than a de novo synthesis; adenine phosphoribosyltransferase 1228074 apt 8111844 apt Streptococcus dysgalactiae subsp. equisimilis GGS_124 adenine phosphoribosyltransferase YP_002996987.1 1227556 R 486410 CDS YP_002996988.1 251782685 8112329 complement(1228222..1230429) 1 NC_012891.1 similar to single-stranded-DNA-specific exonuclease [Streptococcus pyogenes MGAS5005]; single-stranded-DNA-specific exonuclease 1230429 recJ 8112329 recJ Streptococcus dysgalactiae subsp. equisimilis GGS_124 single-stranded-DNA-specific exonuclease YP_002996988.1 1228222 R 486410 CDS YP_002996989.1 251782686 8111035 complement(1230426..1231190) 1 NC_012891.1 similar to short chain dehydrogenase [Streptococcus pyogenes MGAS10394]; short chain dehydrogenase 1231190 8111035 SDEG_1280 Streptococcus dysgalactiae subsp. equisimilis GGS_124 short chain dehydrogenase YP_002996989.1 1230426 R 486410 CDS YP_002996990.1 251782687 8111587 complement(1231190..1232119) 1 NC_012891.1 member of metallo-beta-lactamase family; the purified enzyme from Escherichia coli forms dimeric zinc phosphodiesterase; in Bacillus subtilis this protein is a 3'-tRNA processing endoribonuclease and is essential while in Escherichia coli it is not; associates with two zinc ions; ribonuclease Z 1232119 elaC 8111587 elaC Streptococcus dysgalactiae subsp. equisimilis GGS_124 ribonuclease Z YP_002996990.1 1231190 R 486410 CDS YP_002996991.1 251782688 8111868 complement(1232134..1232769) 1 NC_012891.1 similar to hypothetical protein spyM18 0980 [Streptococcus pyogenes MGAS8232]; hypothetical protein 1232769 8111868 SDEG_1282 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996991.1 1232134 R 486410 CDS YP_002996992.1 251782689 8111588 complement(1232762..1234012) 1 NC_012891.1 similar to HflX [Streptococcus pyogenes MGAS10394]; GTP-binding protein HflX 1234012 hflX 8111588 hflX Streptococcus dysgalactiae subsp. equisimilis GGS_124 GTP-binding protein HflX YP_002996992.1 1232762 R 486410 CDS YP_002996993.1 251782690 8112030 complement(1234088..1234972) 1 NC_012891.1 IPP transferase; isopentenyltransferase; involved in tRNA modification; in Escherichia coli this enzyme catalyzes the addition of a delta2-isopentenyl group from dimethylallyl diphosphate to the N6-nitrogen of adenosine adjacent to the anticodon of tRNA species that read codons starting with uracil; further tRNA modifications may occur; mutations in miaA result in defects in translation efficiency and fidelity; tRNA delta(2)-isopentenylpyrophosphate transferase 1234972 miaA 8112030 miaA Streptococcus dysgalactiae subsp. equisimilis GGS_124 tRNA delta(2)-isopentenylpyrophosphate transferase YP_002996993.1 1234088 R 486410 CDS YP_002996994.1 251782691 8110938 1235105..1235281 1 NC_012891.1 similar to hypothetical protein M6 Spy0747 [Streptococcus pyogenes MGAS10394]; hypothetical protein 1235281 8110938 SDEG_1285 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996994.1 1235105 D 486410 CDS YP_002996995.1 251782692 8111589 complement(1235386..1236327) 1 NC_012891.1 similar to exfoliative toxin [Streptococcus pyogenes MGAS10394]; exfoliative toxin 1236327 8111589 SDEG_1286 Streptococcus dysgalactiae subsp. equisimilis GGS_124 exfoliative toxin YP_002996995.1 1235386 R 486410 CDS YP_002996996.1 251782693 8111590 complement(1236486..1237094) 1 NC_012891.1 similar to glutathione S-transferase [Streptococcus pyogenes MGAS10750]; glutathione S-transferase 1237094 8111590 SDEG_1287 Streptococcus dysgalactiae subsp. equisimilis GGS_124 glutathione S-transferase YP_002996996.1 1236486 R 486410 CDS YP_002996997.1 251782694 8111591 complement(1237173..1237658) 1 NC_012891.1 similar to hypothetical protein Sez 1253 [Streptococcus equi subsp. zooepidemicus MGCS10565]; hypothetical protein 1237658 8111591 SDEG_1288 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996997.1 1237173 R 486410 CDS YP_002996998.1 251782695 8111592 complement(1237878..1238864) 1 NC_012891.1 similar to hypothetical protein SpyM51090 [Streptococcus pyogenes str. Manfredo]; hypothetical protein 1238864 8111592 SDEG_1289 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996998.1 1237878 R 486410 CDS YP_002996999.1 251782696 8111593 1239059..1239361 1 NC_012891.1 similar to hypothetical protein Spy49 0725c [Streptococcus pyogenes NZ131]; hypothetical protein 1239361 8111593 SDEG_1290 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002996999.1 1239059 D 486410 CDS YP_002997000.1 251782697 8111594 complement(1239426..1239980) 1 NC_012891.1 similar to NADPH-dependent FMN reductase [Bacillus coagulans 36D1]; NADPH-dependent FMN reductase 1239980 8111594 SDEG_1291 Streptococcus dysgalactiae subsp. equisimilis GGS_124 NADPH-dependent FMN reductase YP_002997000.1 1239426 R 486410 CDS YP_002997001.1 251782698 8111595 complement(1240217..1242481) 1 NC_012891.1 similar to glycogen phosphorylase [Streptococcus pyogenes MGAS10394]; glycogen phosphorylase 1242481 glgP 8111595 glgP Streptococcus dysgalactiae subsp. equisimilis GGS_124 glycogen phosphorylase YP_002997001.1 1240217 R 486410 CDS YP_002997002.1 251782699 8112000 complement(1242512..1244008) 1 NC_012891.1 amylomaltase; acts to release glucose from maltodextrins; 4-alpha-glucanotransferase 1244008 malQ 8112000 malQ Streptococcus dysgalactiae subsp. equisimilis GGS_124 4-alpha-glucanotransferase YP_002997002.1 1242512 R 486410 CDS YP_002997003.1 251782700 8110924 complement(1244127..1245146) 1 NC_012891.1 similar to maltose operon transcriptional repressor MalR [Streptococcus equi subsp. zooepidemicus MGCS10565]; maltose operon transcriptional repressor 1245146 malR 8110924 malR Streptococcus dysgalactiae subsp. equisimilis GGS_124 maltose operon transcriptional repressor YP_002997003.1 1244127 R 486410 CDS YP_002997004.1 251782701 8110925 1245384..1246412 1 NC_012891.1 similar to transposase [Streptococcus pyogenes MGAS10270]; transposase 1246412 8110925 SDEG_1295 Streptococcus dysgalactiae subsp. equisimilis GGS_124 transposase YP_002997004.1 1245384 D 486410 CDS YP_002997005.1 251782702 8111596 1246568..1247821 1 NC_012891.1 similar to maltose/maltodextrin-binding protein [Streptococcus pyogenes MGAS10750]; maltose/maltodextrin-binding protein 1247821 malE 8111596 malE Streptococcus dysgalactiae subsp. equisimilis GGS_124 maltose/maltodextrin-binding protein YP_002997005.1 1246568 D 486410 CDS YP_002997006.1 251782703 8110920 1248102..1249463 1 NC_012891.1 similar to maltose/maltodextrin ABC transport system (permease) [Streptococcus pyogenes M1 GAS]; maltose/maltodextrin ABC transportsystem (permease) 1249463 malF 8110920 malF Streptococcus dysgalactiae subsp. equisimilis GGS_124 maltose/maltodextrin ABC transportsystem (permease) YP_002997006.1 1248102 D 486410 CDS YP_002997007.1 251782704 8110921 1249463..1250299 1 NC_012891.1 similar to MalG [Streptococcus pyogenes MGAS10394]; maltose transport system permease 1250299 malG 8110921 malG Streptococcus dysgalactiae subsp. equisimilis GGS_124 maltose transport system permease YP_002997007.1 1249463 D 486410 CDS YP_002997008.1 251782705 8110922 1250472..1251269 1 NC_012891.1 similar to transcriptional regulator, LacI family [Streptococcus pyogenes MGAS10270]; LacI family transcriptional regulator 1251269 8110922 SDEG_1299 Streptococcus dysgalactiae subsp. equisimilis GGS_124 LacI family transcriptional regulator YP_002997008.1 1250472 D 486410 CDS YP_002997009.1 251782706 8111111 complement(1251343..1252170) 1 NC_012891.1 similar to maltodextrose utilization protein malA [Streptococcus pyogenes MGAS10270]; maltodextrose utilization protein 1252170 malA 8111111 malA Streptococcus dysgalactiae subsp. equisimilis GGS_124 maltodextrose utilization protein YP_002997009.1 1251343 R 486410 CDS YP_002997010.1 251782707 8110916 complement(1252192..1253052) 1 NC_012891.1 similar to maltodextrin transport system permease protein malD [Streptococcus pyogenes MGAS10270]; maltodextrin transport system permease 1253052 malD 8110916 malD Streptococcus dysgalactiae subsp. equisimilis GGS_124 maltodextrin transport system permease YP_002997010.1 1252192 R 486410 CDS YP_002997011.1 251782708 8110919 complement(1253052..1253180) 1 NC_012891.1 similar to maltose transport system permease protein [Streptococcus pyogenes MGAS5005]; maltose transport system permease 1253180 malC 8110919 malC Streptococcus dysgalactiae subsp. equisimilis GGS_124 maltose transport system permease YP_002997011.1 1253052 R 486410 CDS YP_002997012.1 251782709 8110917 complement(1253284..1254357) 1 NC_012891.1 similar to maltodextrin transport system permease protein malC [Streptococcus pyogenes MGAS10270]; maltodextrin transport system permease 1254357 malC 8110917 malC Streptococcus dysgalactiae subsp. equisimilis GGS_124 maltodextrin transport system permease YP_002997012.1 1253284 R 486410 CDS YP_002997013.1 251782710 8110918 complement(1254480..1256183) 1 NC_012891.1 similar to neopullulanase/cyclomaltodextrinase/ maltogenic alpha-amylase [Streptococcus pyogenes MGAS5005]; neopullulanase 1256183 amyB 8110918 amyB Streptococcus dysgalactiae subsp. equisimilis GGS_124 neopullulanase YP_002997013.1 1254480 R 486410 CDS YP_002997014.1 251782711 8112323 complement(1256348..1257601) 1 NC_012891.1 similar to maltose/maltodextrin-binding protein [Streptococcus pyogenes MGAS6180]; maltose/maltodextrin-binding protein 1257601 malX 8112323 malX Streptococcus dysgalactiae subsp. equisimilis GGS_124 maltose/maltodextrin-binding protein YP_002997014.1 1256348 R 486410 CDS YP_002997015.1 251782712 8110926 complement(1258005..1259261) 1 NC_012891.1 similar to secreted protein DltD [Streptococcus pyogenes MGAS315]; hypothetical protein 1259261 dltD 8110926 dltD Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002997015.1 1258005 R 486410 CDS YP_002997016.1 251782713 8111841 complement(1259254..1259493) 1 NC_012891.1 D-alanyl carrier protein subunit; involved in the incorporation of D-alanine into membrane-associated D-alanyl-lipoteichoic acid; D-alanyl carrier protein is the acceptor of activated D-alanine which it donates to a membrane acceptor(D-alanyl transferase) for incorporation into membrane lipoteichoic acid; D-alanine--poly(phosphoribitol) ligase subunit 2 1259493 dltC 8111841 dltC Streptococcus dysgalactiae subsp. equisimilis GGS_124 D-alanine--poly(phosphoribitol) ligase subunit 2 YP_002997016.1 1259254 R 486410 CDS YP_002997017.1 251782714 8111840 complement(1259511..1260767) 1 NC_012891.1 similar to DltB [Streptococcus pyogenes MGAS10394]; D-alanyl transfer protein 1260767 dltB 8111840 dltB Streptococcus dysgalactiae subsp. equisimilis GGS_124 D-alanyl transfer protein YP_002997017.1 1259511 R 486410 CDS YP_002997018.1 251782715 8111677 complement(1260764..1262302) 1 NC_012891.1 transfers D-alanine to the D-alanyl carrier protein during the incorporation of D-alanine into lipoteichoic acid; D-alanine--poly(phosphoribitol) ligase subunit 1 1262302 dltA 8111677 dltA Streptococcus dysgalactiae subsp. equisimilis GGS_124 D-alanine--poly(phosphoribitol) ligase subunit 1 YP_002997018.1 1260764 R 486410 CDS YP_002997019.1 251782716 8111676 complement(1262314..1262457) 1 NC_012891.1 similar to hypothetical protein spyM18 1325 [Streptococcus pyogenes MGAS8232]; hypothetical protein 1262457 8111676 SDEG_1310 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002997019.1 1262314 R 486410 CDS YP_002997020.1 251782717 8111112 complement(1262710..1264701) 1 NC_012891.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion; excinuclease ABC subunit B 1264701 uvrB 8111112 uvrB Streptococcus dysgalactiae subsp. equisimilis GGS_124 excinuclease ABC subunit B YP_002997020.1 1262710 R 486410 CDS YP_002997021.1 251782718 8111945 1264888..1267065 1 NC_012891.1 similar to glutamine-binding protein/glutamine transport system permease protein glnP [Streptococcus pyogenes MGAS10270]; glutamine-binding protein/glutamine transportsystem permease 1267065 glnH 8111945 glnH Streptococcus dysgalactiae subsp. equisimilis GGS_124 glutamine-binding protein/glutamine transportsystem permease YP_002997021.1 1264888 D 486410 CDS YP_002997022.1 251782719 8112003 1267065..1267805 1 NC_012891.1 similar to glutamine transport ATP-binding protein [Streptococcus pyogenes MGAS5005]; glutamine transport ATP-binding protein 1267805 glnQ.2 8112003 glnQ.2 Streptococcus dysgalactiae subsp. equisimilis GGS_124 glutamine transport ATP-binding protein YP_002997022.1 1267065 D 486410 CDS YP_002997023.1 251782720 8112005 1268107..1268568 1 NC_012891.1 similar to nicotinamide mononucleotide transporter [Streptococcus pyogenes MGAS6180]; nicotinamide mononucleotide transporter 1268568 8112005 SDEG_1314 Streptococcus dysgalactiae subsp. equisimilis GGS_124 nicotinamide mononucleotide transporter YP_002997023.1 1268107 D 486410 CDS YP_002997024.1 251782721 8111113 complement(1268792..1270105) 1 NC_012891.1 essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication; GTPase ObgE 1270105 obgE 8111113 obgE Streptococcus dysgalactiae subsp. equisimilis GGS_124 GTPase ObgE YP_002997024.1 1268792 R 486410 CDS YP_002997025.1 251782722 8111731 complement(1270160..1270288) 1 NC_012891.1 similar to hypothetical protein MGAS2096 Spy1090 [Streptococcus pyogenes MGAS2096]; hypothetical protein 1270288 8111731 SDEG_1316 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002997025.1 1270160 R 486410 CDS YP_002997026.1 251782723 8111114 1270465..1271706 1 NC_012891.1 similar to aminopeptidase PepS [Streptococcus equi subsp. zooepidemicus MGCS10565]; aminopeptidase 1271706 pepS 8111114 pepS Streptococcus dysgalactiae subsp. equisimilis GGS_124 aminopeptidase YP_002997026.1 1270465 D 486410 CDS YP_002997027.1 251782724 8111279 1271766..1272683 1 NC_012891.1 similar to hypothetical protein ANACAC 02747 [anaerostipes caccae DSM 14662]; hypothetical protein 1272683 8111279 SDEG_1318 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002997027.1 1271766 D 486410 CDS YP_002997028.1 251782725 8111115 complement(1272734..1273471) 1 NC_012891.1 similar to ribosomal small subunit pseudouridine synthase A [Streptococcus pyogenes MGAS5005]; ribosomal small subunit pseudouridine synthaseA 1273471 rsuA 8111115 rsuA Streptococcus dysgalactiae subsp. equisimilis GGS_124 ribosomal small subunit pseudouridine synthaseA YP_002997028.1 1272734 R 486410 CDS YP_002997029.1 251782726 8110450 1273581..1273946 1 NC_012891.1 similar to hypothetical protein MGAS10750 Spy1192 [Streptococcus pyogenes MGAS10750]; hypothetical protein 1273946 8110450 SDEG_1320 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002997029.1 1273581 D 486410 CDS YP_002997030.1 251782727 8111116 complement(1274045..1275265) 1 NC_012891.1 similar to transporter MFS superfamily [Streptococcus pyogenes MGAS5005]; MFS superfamily transporter 1275265 8111116 SDEG_1321 Streptococcus dysgalactiae subsp. equisimilis GGS_124 MFS superfamily transporter YP_002997030.1 1274045 R 486410 CDS YP_002997031.1 251782728 8111117 1275629..1277122 1 NC_012891.1 similar to hypothetical cytosolic protein [Streptococcus pyogenes MGAS5005]; hypothetical protein 1277122 8111117 SDEG_1322 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002997031.1 1275629 D 486410 CDS YP_002997032.1 251782729 8111118 complement(1277199..1277969) 1 NC_012891.1 similar to hypothetical protein SAG0689 [Streptococcus agalactiae 2603V/R]; hypothetical protein 1277969 8111118 SDEG_1323 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002997032.1 1277199 R 486410 CDS YP_002997033.1 251782730 8111119 complement(1277966..1278622) 1 NC_012891.1 similar to ABC transporter ATP-binding protein [Streptococcus agalactiae 2603V/R]; ABC transporter ATP-binding protein 1278622 8111119 SDEG_1324 Streptococcus dysgalactiae subsp. equisimilis GGS_124 ABC transporter ATP-binding protein YP_002997033.1 1277966 R 486410 CDS YP_002997034.1 251782731 8111120 complement(1278826..1279218) 1 NC_012891.1 similar to thioesterase superfamily protein [Streptococcus pyogenes MGAS2096]; thioesterase 1279218 8111120 SDEG_1325 Streptococcus dysgalactiae subsp. equisimilis GGS_124 thioesterase YP_002997034.1 1278826 R 486410 CDS YP_002997035.1 251782732 8111121 complement(1279300..1280094) 1 NC_012891.1 similar to uridine phosphorylase [Streptococcus thermophilus LMD-9]; uridine phosphorylase 1280094 8111121 SDEG_1326 Streptococcus dysgalactiae subsp. equisimilis GGS_124 uridine phosphorylase YP_002997035.1 1279300 R 486410 CDS YP_002997036.1 251782733 8111122 complement(1280241..1281080) 1 NC_012891.1 similar to YaeC family protein [Streptococcus agalactiae 2603V/R]; YaeC family protein 1281080 8111122 SDEG_1327 Streptococcus dysgalactiae subsp. equisimilis GGS_124 YaeC family protein YP_002997036.1 1280241 R 486410 CDS YP_002997037.1 251782734 8111123 1281659..1281949 1 NC_012891.1 similar to ISSdy1, transposase OrfA [Streptococcus agalactiae 515]; ISSdy1, transposase OrfA 1281949 8111123 SDEG_1328 Streptococcus dysgalactiae subsp. equisimilis GGS_124 ISSdy1, transposase OrfA YP_002997037.1 1281659 D 486410 CDS YP_002997038.1 251782735 8111124 1281985..1282764 1 NC_012891.1 similar to ISSdy1, transposase OrfB [Streptococcus agalactiae 2603V/R]; ISSdy1, transposase OrfB 1282764 8111124 SDEG_1329 Streptococcus dysgalactiae subsp. equisimilis GGS_124 ISSdy1, transposase OrfB YP_002997038.1 1281985 D 486410 CDS YP_002997039.1 251782736 8111125 complement(1282855..1283577) 1 NC_012891.1 similar to ATPase component of ABC transporters with duplicated ATPase domains [Streptococcus suis 98HAH33]; ABC transporter ATPase 1283577 8111125 SDEG_1330 Streptococcus dysgalactiae subsp. equisimilis GGS_124 ABC transporter ATPase YP_002997039.1 1282855 R 486410 CDS YP_002997040.1 251782737 8111126 complement(1283607..1284233) 1 NC_012891.1 similar to ABC transporter ATP-binding protein [Streptococcus equi subsp.; hypothetical protein 1284233 8111126 SDEG_1331 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002997040.1 1283607 R 486410 CDS YP_002997041.1 251782738 8111127 complement(1284257..1286038) 1 NC_012891.1 similar to ABC transporter ATP-binding protein/peptidase [Treponema denticola ATCC 35405]; ABC transporter ATP-binding protein/peptidase 1286038 8111127 SDEG_1332 Streptococcus dysgalactiae subsp. equisimilis GGS_124 ABC transporter ATP-binding protein/peptidase YP_002997041.1 1284257 R 486410 CDS YP_002997042.1 251782739 8111128 complement(1286136..1286828) 1 NC_012891.1 similar to hypothetical protein llmg 0328 [Lactococcus lactis subsp. cremoris MG1363]; hypothetical protein 1286828 8111128 SDEG_1333 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002997042.1 1286136 R 486410 CDS YP_002997043.1 251782740 8111129 1287230..1288102 1 NC_012891.1 similar to transcriptional regulator PlcR [Streptococcus pneumoniae SP3-BS71]; transcriptional regulator PlcR 1288102 8111129 SDEG_1334 Streptococcus dysgalactiae subsp. equisimilis GGS_124 transcriptional regulator PlcR YP_002997043.1 1287230 D 486410 CDS YP_002997044.1 251782741 8111130 complement(1288145..1289539) 1 NC_012891.1 similar to relaxase [Streptococcus macedonicus]; relaxase 1289539 8111130 SDEG_1335 Streptococcus dysgalactiae subsp. equisimilis GGS_124 relaxase YP_002997044.1 1288145 R 486410 CDS YP_002997045.1 251782742 8111131 1289576..1289890 1 NC_012891.1 similar to transposase [Streptococcus pyogenes MGAS6180]; transposase 1289890 8111131 SDEG_1336 Streptococcus dysgalactiae subsp. equisimilis GGS_124 transposase YP_002997045.1 1289576 D 486410 CDS YP_002997046.1 251782743 8111132 1289943..1290746 1 NC_012891.1 similar to transposase [Streptococcus pyogenes MGAS10270]; transposase 1290746 8111132 SDEG_1337 Streptococcus dysgalactiae subsp. equisimilis GGS_124 transposase YP_002997046.1 1289943 D 486410 CDS YP_002997047.1 251782744 8111133 complement(1290778..1291107) 1 NC_012891.1 similar to hypothetical protein PEPMIC 00594 [Peptostreptococcus micros ATCC 33270]; hypothetical protein 1291107 8111133 SDEG_1338 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002997047.1 1290778 R 486410 CDS YP_002997048.1 251782745 8111134 complement(1291182..1291346) 1 NC_012891.1 similar to hypothetical protein PEPMIC 00190 [Peptostreptococcus micros ATCC 33270]; hypothetical protein 1291346 8111134 SDEG_1339 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002997048.1 1291182 R 486410 CDS YP_002997049.1 251782746 8111135 complement(1291439..1292212) 1 NC_012891.1 similar to hypothetical protein EUBDOL 02334 [Eubacterium dolichum DSM 3991]; hypothetical protein 1292212 8111135 SDEG_1340 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002997049.1 1291439 R 486410 CDS YP_002997050.1 251782747 8111136 complement(1292370..1293854) 1 NC_012891.1 similar to hypothetical protein PEPMIC 00192 [Peptostreptococcus micros ATCC 33270]; hypothetical protein 1293854 8111136 SDEG_1341 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002997050.1 1292370 R 486410 CDS YP_002997051.1 251782748 8111137 complement(1293933..1294052) 1 NC_012891.1 similar to hypothetical protein PEPMIC 00193 [Peptostreptococcus micros ATCC 33270]; hypothetical protein 1294052 8111137 SDEG_1342 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002997051.1 1293933 R 486410 CDS YP_002997052.1 251782749 8111138 complement(1294095..1294415) 1 NC_012891.1 similar to hypothetical protein PEPMIC 00194 [Peptostreptococcus micros ATCC 33270]; hypothetical protein 1294415 8111138 SDEG_1343 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002997052.1 1294095 R 486410 CDS YP_002997053.1 251782750 8111139 complement(1294488..1294685) 1 NC_012891.1 similar to hypothetical protein TDE2175 [Treponema denticola ATCC 35405]; hypothetical protein 1294685 8111139 SDEG_1344 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002997053.1 1294488 R 486410 CDS YP_002997054.1 251782751 8111140 complement(1294765..1296603) 1 NC_012891.1 similar to site-specific recombinase [Treponema denticola ATCC 35405]; site-specific recombinase 1296603 8111140 SDEG_1345 Streptococcus dysgalactiae subsp. equisimilis GGS_124 site-specific recombinase YP_002997054.1 1294765 R 486410 CDS YP_002997055.1 251782752 8111141 complement(1296654..1296992) 1 NC_012891.1 similar to hypothetical protein PEPMIC 00594 [Peptostreptococcus micros ATCC 33270]; hypothetical protein 1296992 8111141 SDEG_1346 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002997055.1 1296654 R 486410 CDS YP_002997056.1 251782753 8111142 complement(1296989..1297474) 1 NC_012891.1 similar to hypothetical protein PEPMIC 00593 [Peptostreptococcus micros ATCC 33270]; hypothetical protein 1297474 8111142 SDEG_1347 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002997056.1 1296989 R 486410 CDS YP_002997057.1 251782754 8111143 complement(1297471..1298322) 1 NC_012891.1 similar to hypothetical protein PEPMIC 00592 [Peptostreptococcus micros ATCC 33270]; hypothetical protein 1298322 8111143 SDEG_1348 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002997057.1 1297471 R 486410 CDS YP_002997058.1 251782755 8111144 complement(1298319..1299098) 1 NC_012891.1 similar to hypothetical protein PEPMIC 00591 [Peptostreptococcus micros ATCC 33270]; hypothetical protein 1299098 8111144 SDEG_1349 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002997058.1 1298319 R 486410 CDS YP_002997059.1 251782756 8111145 complement(1299629..1300990) 1 NC_012891.1 similar to hypothetical protein PEPMIC 00591 [Peptostreptococcus micros ATCC 33270]; hypothetical protein 1300990 8111145 SDEG_1350 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002997059.1 1299629 R 486410 CDS YP_002997060.1 251782757 8111146 complement(1301076..1302548) 1 NC_012891.1 similar to PBP 5 synthesis repressor [Streptococcus pyogenes MGAS8232]; PBP 5 synthesis repressor 1302548 8111146 SDEG_1351 Streptococcus dysgalactiae subsp. equisimilis GGS_124 PBP 5 synthesis repressor YP_002997060.1 1301076 R 486410 CDS YP_002997061.1 251782758 8111147 complement(1302779..1303270) 1 NC_012891.1 catalyzes the formation of shikimate 3-phosphate from shikimate in aromatic amino acid biosynthesis; shikimate kinase 1303270 aroK 8111147 aroK Streptococcus dysgalactiae subsp. equisimilis GGS_124 shikimate kinase YP_002997061.1 1302779 R 486410 CDS YP_002997062.1 251782759 8112343 complement(1303263..1304555) 1 NC_012891.1 catalyzes the formation of 5-O-(1-carboxyvinyl)-3-phosphoshikimate from phosphoenolpyruvate and 3-phosphoshikimate in tryptophan biosynthesis; 3-phosphoshikimate 1-carboxyvinyltransferase 1304555 8112343 SDEG_1353 Streptococcus dysgalactiae subsp. equisimilis GGS_124 3-phosphoshikimate 1-carboxyvinyltransferase YP_002997062.1 1303263 R 486410 CDS YP_002997063.1 251782760 8111148 complement(1304653..1305609) 1 NC_012891.1 similar to ribonuclease BN [Streptococcus pyogenes MGAS10394]; ribonuclease BN 1305609 8111148 SDEG_1354 Streptococcus dysgalactiae subsp. equisimilis GGS_124 ribonuclease BN YP_002997063.1 1304653 R 486410 CDS YP_002997064.1 251782761 8111149 complement(1305611..1306471) 1 NC_012891.1 catalyzes the removal of N-terminal amino acids from peptides and arylamides; methionine aminopeptidase 1306471 map 8111149 map Streptococcus dysgalactiae subsp. equisimilis GGS_124 methionine aminopeptidase YP_002997064.1 1305611 R 486410 CDS YP_002997065.1 251782762 8110932 complement(1306488..1307783) 1 NC_012891.1 similar to cytosolic protein containing multiple CBS domains [Streptococcus pyogenes MGAS10750]; hypothetical protein 1307783 8110932 SDEG_1356 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002997065.1 1306488 R 486410 CDS YP_002997066.1 251782763 8111150 complement(1307764..1308318) 1 NC_012891.1 similar to acetyltransferase GNAT family [Streptococcus equi subsp. zooepidemicus MGCS10565]; GNAT family acetyltransferase 1308318 8111150 SDEG_1357 Streptococcus dysgalactiae subsp. equisimilis GGS_124 GNAT family acetyltransferase YP_002997066.1 1307764 R 486410 CDS YP_002997067.1 251782764 8111151 complement(1308567..1310138) 1 NC_012891.1 similar to immunoglobulin G-binding protein G precursor (IgG-binding protein G); immunoglobulin G-binding protein 1310138 spg 8111151 spg Streptococcus dysgalactiae subsp. equisimilis GGS_124 immunoglobulin G-binding protein YP_002997067.1 1308567 R 486410 CDS YP_002997068.1 251782765 8110496 complement(1310620..1312416) 1 NC_012891.1 similar to glycosyl hydrolase family 3 [Streptococcus agalactiae 515]; glycosyl hydrolase 1312416 8110496 SDEG_1359 Streptococcus dysgalactiae subsp. equisimilis GGS_124 glycosyl hydrolase YP_002997068.1 1310620 R 486410 CDS YP_002997069.1 251782766 8111152 complement(1312532..1313335) 1 NC_012891.1 similar to phosphoglycolate phosphatase [Streptococcus pyogenes MGAS10270]; phosphoglycolate phosphatase 1313335 8111152 SDEG_1360 Streptococcus dysgalactiae subsp. equisimilis GGS_124 phosphoglycolate phosphatase YP_002997069.1 1312532 R 486410 CDS YP_002997070.1 251782767 8111153 complement(1313604..1314443) 1 NC_012891.1 Converts D-mannonate to D-mannuronate; D-mannonate oxidoreductase 1314443 8111153 SDEG_1361 Streptococcus dysgalactiae subsp. equisimilis GGS_124 D-mannonate oxidoreductase YP_002997070.1 1313604 R 486410 CDS YP_002997071.1 251782768 8111154 complement(1314458..1315558) 1 NC_012891.1 catalyzes the formation of 2-dehydro-3-deoxy-D-gluconate from mannonate; mannonate dehydratase 1315558 8111154 SDEG_1362 Streptococcus dysgalactiae subsp. equisimilis GGS_124 mannonate dehydratase YP_002997071.1 1314458 R 486410 CDS YP_002997072.1 251782769 8111155 complement(1315647..1316861) 1 NC_012891.1 catalyzes the interconversion of D-glucuronate to D-fructuronate or D-galacturonate to D-tagaturonate; functions in glucuronic and galacturonic metabolism; glucuronate isomerase 1316861 8111155 SDEG_1363 Streptococcus dysgalactiae subsp. equisimilis GGS_124 glucuronate isomerase YP_002997072.1 1315647 R 486410 CDS YP_002997073.1 251782770 8111156 complement(1316970..1317071) 1 NC_012891.1 similar to uronate isomerase [Streptococcus pyogenes MGAS10270]; uronate isomerase 1317071 8111156 SDEG_1364 Streptococcus dysgalactiae subsp. equisimilis GGS_124 uronate isomerase YP_002997073.1 1316970 R 486410 CDS YP_002997074.1 251782771 8111157 complement(1317074..1317691) 1 NC_012891.1 similar to 4-hydroxy-2-oxoglutarate aldolase / 2-dehydro-3-deoxyphosphogluconate aldolase [Streptococcus pyogenes MGAS10270]; 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxyphosphogluconate aldolase 1317691 8111157 SDEG_1365 Streptococcus dysgalactiae subsp. equisimilis GGS_124 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxyphosphogluconate aldolase YP_002997074.1 1317074 R 486410 CDS YP_002997075.1 251782772 8111158 complement(1317819..1318490) 1 NC_012891.1 similar to transcriptional regulator GntR family [Streptococcus pyogenes MGAS10270]; GntR family transcriptional regulator 1318490 8111158 SDEG_1366 Streptococcus dysgalactiae subsp. equisimilis GGS_124 GntR family transcriptional regulator YP_002997075.1 1317819 R 486410 CDS YP_002997076.1 251782773 8111159 complement(1318532..1320322) 1 NC_012891.1 similar to beta-glucuronidase [Streptococcus pyogenes MGAS10270]; beta-D-glucuronidase 1320322 8111159 SDEG_1367 Streptococcus dysgalactiae subsp. equisimilis GGS_124 beta-D-glucuronidase YP_002997076.1 1318532 R 486410 CDS YP_002997077.1 251782774 8111160 complement(1320345..1321373) 1 NC_012891.1 similar to 2-dehydro-3-deoxygluconokinase [Streptococcus pyogenes MGAS10270]; 2-dehydro-3-deoxygluconokinase 1321373 8111160 SDEG_1368 Streptococcus dysgalactiae subsp. equisimilis GGS_124 2-dehydro-3-deoxygluconokinase YP_002997077.1 1320345 R 486410 CDS YP_002997078.1 251782775 8111161 complement(1321526..1323070) 1 NC_012891.1 similar to sugar /sodium symporter [Streptococcus pyogenes MGAS10270]; sugar/sodium symporter 1323070 8111161 SDEG_1369 Streptococcus dysgalactiae subsp. equisimilis GGS_124 sugar/sodium symporter YP_002997078.1 1321526 R 486410 CDS YP_002997079.1 251782776 8111162 complement(1323414..1324673) 1 NC_012891.1 adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active; UDP-N-acetylglucosamine 1-carboxyvinyltransferase 1324673 murZ 8111162 murZ Streptococcus dysgalactiae subsp. equisimilis GGS_124 UDP-N-acetylglucosamine 1-carboxyvinyltransferase YP_002997079.1 1323414 R 486410 CDS YP_002997080.1 251782777 8111692 complement(1324862..1326058) 1 NC_012891.1 catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase; S-adenosylmethionine synthetase 1326058 metK2 8111692 metK2 Streptococcus dysgalactiae subsp. equisimilis GGS_124 S-adenosylmethionine synthetase YP_002997080.1 1324862 R 486410 CDS YP_002997081.1 251782778 8110935 complement(1326553..1328919) 1 NC_012891.1 similar to internalin protein [Streptococcus pyogenes MGAS10394]; internalin protein 1328919 inlA 8110935 inlA Streptococcus dysgalactiae subsp. equisimilis GGS_124 internalin protein YP_002997081.1 1326553 R 486410 CDS YP_002997082.1 251782779 8112054 1329095..1330036 1 NC_012891.1 catalyzes the formation of biotinyl-5'-AMP, also acts as a transcriptional repressor of the biotin operon; biotin--protein ligase 1330036 birA 8112054 birA Streptococcus dysgalactiae subsp. equisimilis GGS_124 biotin--protein ligase YP_002997082.1 1329095 D 486410 CDS YP_002997083.1 251782780 8112377 complement(1330011..1330259) 1 NC_012891.1 similar to hypothetical protein M28 Spy1103 [Streptococcus pyogenes MGAS6180]; hypothetical protein 1330259 8112377 SDEG_1374 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002997083.1 1330011 R 486410 CDS YP_002997084.1 251782781 8111163 complement(1330433..1332112) 1 NC_012891.1 catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the tau chain serves as a scaffold to help in the dimerizaton of the alpha,epsilon and theta core complex; the gamma chain seems to interact with the delta and delta' subunits to transfer the beta subunit on the DNA; DNA polymerase III subunits gamma and tau 1332112 8111163 SDEG_1375 Streptococcus dysgalactiae subsp. equisimilis GGS_124 DNA polymerase III subunits gamma and tau YP_002997084.1 1330433 R 486410 CDS YP_002997085.1 251782782 8111164 complement(1332112..1332642) 1 NC_012891.1 similar to GAF domain-containing proteins [Streptococcus pyogenes MGAS6180]; GAF domain-containing proteins 1332642 8111164 SDEG_1376 Streptococcus dysgalactiae subsp. equisimilis GGS_124 GAF domain-containing proteins YP_002997085.1 1332112 R 486410 CDS YP_002997086.1 251782783 8111165 1332749..1333564 1 NC_012891.1 similar to hypothetical protein SPy 1366 [Streptococcus pyogenes M1 GAS]; hypothetical protein 1333564 8111165 SDEG_1377 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002997086.1 1332749 D 486410 CDS YP_002997087.1 251782784 8111166 complement(1333609..1333881) 1 NC_012891.1 similar to hypothetical membrane spanning protein [Streptococcus pyogenes MGAS10394]; hypothetical protein 1333881 8111166 SDEG_1378 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002997087.1 1333609 R 486410 CDS YP_002997088.1 251782785 8111167 complement(1333942..1334580) 1 NC_012891.1 functions in pyrimidine salvage; pyrimidine ribonucleoside kinase; phosphorylates nucleosides or dinucleosides to make UMP or CMP using ATP or GTP as the donor; uridine kinase 1334580 udk 8111167 udk Streptococcus dysgalactiae subsp. equisimilis GGS_124 uridine kinase YP_002997088.1 1333942 R 486410 CDS YP_002997089.1 251782786 8111938 1334633..1335751 1 NC_012891.1 similar to ATP-dependent RNA helicase [Streptococcus pyogenes MGAS10394]; ATP-dependent RNA helicase 1335751 deaD 8111938 deaD Streptococcus dysgalactiae subsp. equisimilis GGS_124 ATP-dependent RNA helicase YP_002997089.1 1334633 D 486410 CDS YP_002997090.1 251782787 8111664 1336019..1336546 1 NC_012891.1 similar to transposase [Streptococcus pyogenes MGAS10750]; transposase 1336546 8111664 SDEG_1381 Streptococcus dysgalactiae subsp. equisimilis GGS_124 transposase YP_002997090.1 1336019 D 486410 CDS YP_002997091.1 251782788 8111168 1336615..1337130 1 NC_012891.1 similar to transposase [Streptococcus pyogenes MGAS5005]; transposase 1337130 8111168 SDEG_1382 Streptococcus dysgalactiae subsp. equisimilis GGS_124 transposase YP_002997091.1 1336615 D 486410 CDS YP_002997092.1 251782789 8111169 1337155..1337373 1 NC_012891.1 similar to transposase [Streptococcus pyogenes MGAS5005]; transposase 1337373 8111169 SDEG_1383 Streptococcus dysgalactiae subsp. equisimilis GGS_124 transposase YP_002997092.1 1337155 D 486410 CDS YP_002997093.1 251782790 8111170 complement(1337433..1338275) 1 NC_012891.1 similar to haloacid dehalogenase-like hydrolase [Streptococcus suis 89/1591]; haloacid dehalogenase-like hydrolase 1338275 8111170 SDEG_1384 Streptococcus dysgalactiae subsp. equisimilis GGS_124 haloacid dehalogenase-like hydrolase YP_002997093.1 1337433 R 486410 CDS YP_002997094.1 251782791 8111171 complement(1338363..1339067) 1 NC_012891.1 similar to hypothetical protein CLOBAR 01981 [Clostridium bartlettii DSM 16795]; hypothetical protein 1339067 8111171 SDEG_1385 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002997094.1 1338363 R 486410 CDS YP_002997095.1 251782792 8111172 complement(1339240..1340709) 1 NC_012891.1 required for arbutin uptake and metabolism; 6-phospho-beta-glucosidase 1340709 arb 8111172 arb Streptococcus dysgalactiae subsp. equisimilis GGS_124 6-phospho-beta-glucosidase YP_002997095.1 1339240 R 486410 CDS YP_002997096.1 251782793 8111173 complement(1340788..1341390) 1 NC_012891.1 similar to phosphoglycerate mutase family protein [Streptococcus sanguinis SK36]; phosphoglycerate mutase 1341390 8111173 SDEG_1387 Streptococcus dysgalactiae subsp. equisimilis GGS_124 phosphoglycerate mutase YP_002997096.1 1340788 R 486410 CDS YP_002997097.1 251782794 8111174 complement(1341408..1342019) 1 NC_012891.1 similar to hypothetical protein STRINF 01174 [Streptococcus infantarius subsp. infantarius ATCC BAA-102]; hypothetical protein 1342019 8111174 SDEG_1388 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002997097.1 1341408 R 486410 CDS YP_002997098.1 251782795 8111175 complement(1342029..1342634) 1 NC_012891.1 phosphoglycerate mutase 1342634 8111175 SDEG_1389 Streptococcus dysgalactiae subsp. equisimilis GGS_124 phosphoglycerate mutase YP_002997098.1 1342029 R 486410 CDS YP_002997099.1 251782796 8111176 complement(1342768..1343244) 1 NC_012891.1 similar to hypothetical protein lwe2314 [Listeria welshimeri serovar 6b str. SLCC5334]; hypothetical protein 1343244 8111176 SDEG_1390 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002997099.1 1342768 R 486410 CDS YP_002997100.1 251782797 8111177 complement(1343296..1343574) 1 NC_012891.1 similar to hypothetical protein STRINF 01173 [Streptococcus infantarius subsp. infantarius ATCC BAA-102]; hypothetical protein 1343574 8111177 SDEG_1391 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002997100.1 1343296 R 486410 CDS YP_002997101.1 251782798 8111178 complement(1343630..1344376) 1 NC_012891.1 probable ORF of C-terminal portion of glycoside hydrolase, family 1 [Streptococcus suis 89/1591] resulted from mutation by unknown reason; glycoside hydrolase family 1 1344376 8111178 SDEG_1392 Streptococcus dysgalactiae subsp. equisimilis GGS_124 glycoside hydrolase family 1 YP_002997101.1 1343630 R 486410 CDS YP_002997102.1 251782799 8111179 complement(1344373..1344768) 1 NC_012891.1 probable ORF of N-terminal portion of glycoside hydrolase, family 1 [Streptococcus suis 89/1591] resulted from mutation by unknown reason; glycoside hydrolase family 1 1344768 8111179 SDEG_1393 Streptococcus dysgalactiae subsp. equisimilis GGS_124 glycoside hydrolase family 1 YP_002997102.1 1344373 R 486410 CDS YP_002997103.1 251782800 8111180 complement(1344870..1345421) 1 NC_012891.1 similar to acetyltransferase [Clostridium difficile ATCC 43255]; acetyltransferase 1345421 8111180 SDEG_1394 Streptococcus dysgalactiae subsp. equisimilis GGS_124 acetyltransferase YP_002997103.1 1344870 R 486410 CDS YP_002997104.1 251782801 8111181 complement(1345405..1346253) 1 NC_012891.1 similar to haloacid dehalogenase-like hydrolase [Streptococcus gordonii str. Challis substr. CH1]; haloacid dehalogenase-like hydrolase 1346253 8111181 SDEG_1395 Streptococcus dysgalactiae subsp. equisimilis GGS_124 haloacid dehalogenase-like hydrolase YP_002997104.1 1345405 R 486410 CDS YP_002997105.1 251782802 8111182 complement(1346341..1347438) 1 NC_012891.1 similar to hypothetical protein PEPE 0230 [Pediococcus pentosaceus ATCC 25745]; hypothetical protein 1347438 8111182 SDEG_1396 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002997105.1 1346341 R 486410 CDS YP_002997106.1 251782803 8111183 complement(1347508..1348860) 1 NC_012891.1 required for cellobiose uptake and metabolism; cellobiose phosphotransferase system IIC component 1348860 celD 8111183 celD Streptococcus dysgalactiae subsp. equisimilis GGS_124 cellobiose phosphotransferase system IIC component YP_002997106.1 1347508 R 486410 CDS YP_002997107.1 251782804 8111184 complement(1348894..1349400) 1 NC_012891.1 similar to conserved hypothetical protein [Bacillus coagulans 36D1]; hypothetical protein 1349400 8111184 SDEG_1398 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002997107.1 1348894 R 486410 CDS YP_002997108.1 251782805 8111185 complement(1349419..1349739) 1 NC_012891.1 required for cellobiose uptake and metabolism; cellobiose phosphotransferase system IIA component 1349739 celC 8111185 celC Streptococcus dysgalactiae subsp. equisimilis GGS_124 cellobiose phosphotransferase system IIA component YP_002997108.1 1349419 R 486410 CDS YP_002997109.1 251782806 8111186 complement(1349739..1351724) 1 NC_012891.1 similar to transcriptional antiterminator bglG [Streptococcus suis 89/1591]; transcriptional antiterminator bglG 1351724 bglG 8111186 bglG Streptococcus dysgalactiae subsp. equisimilis GGS_124 transcriptional antiterminator bglG YP_002997109.1 1349739 R 486410 CDS YP_002997110.1 251782807 8112374 complement(1351768..1352097) 1 NC_012891.1 required for cellobiose uptake and metabolism; PTS system cellobiose transporter subunit IIB 1352097 celB 8112374 celB Streptococcus dysgalactiae subsp. equisimilis GGS_124 PTS system cellobiose transporter subunit IIB YP_002997110.1 1351768 R 486410 CDS YP_002997111.1 251782808 8111187 complement(1352618..1353397) 1 NC_012891.1 similar to ISSdy1, transposase OrfB [Streptococcus agalactiae 2603V/R]; ISSdy1, transposase OrfB 1353397 8111187 SDEG_1402 Streptococcus dysgalactiae subsp. equisimilis GGS_124 ISSdy1, transposase OrfB YP_002997111.1 1352618 R 486410 CDS YP_002997112.1 251782809 8111188 complement(1353433..1353723) 1 NC_012891.1 similar to ISSag4, transposase orfA [Streptococcus agalactiae A909]; ISSag4, transposase orfA 1353723 8111188 SDEG_1403 Streptococcus dysgalactiae subsp. equisimilis GGS_124 ISSag4, transposase orfA YP_002997112.1 1353433 R 486410 CDS YP_002997113.1 251782810 8111189 complement(1354158..1354460) 1 NC_012891.1 similar to hypothetical protein SsuiDRAFT 1295 [Streptococcus suis 89/1591]; hypothetical protein 1354460 8111189 SDEG_1404 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002997113.1 1354158 R 486410 CDS YP_002997114.1 251782811 8111190 complement(1354684..1355892) 1 NC_012891.1 similar to IS1191 transposase [Streptococcus thermophilus LMG 18311]; IS1191 transposase 1355892 tnp1191 8111190 tnp1191 Streptococcus dysgalactiae subsp. equisimilis GGS_124 IS1191 transposase YP_002997114.1 1354684 R 486410 CDS YP_002997115.1 251782812 8110527 complement(1356132..1356371) 1 NC_012891.1 similar to conserved hypothetical protein [Streptococcus suis 89/1591]; hypothetical protein 1356371 8110527 SDEG_1406 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002997115.1 1356132 R 486410 CDS YP_002997116.1 251782813 8111191 complement(1356388..1357827) 1 NC_012891.1 converts 6-phospho-beta-D-glucosyl-(1,4)-D-glucose to glucose and glucose 6-phosphate; required for cellobiose uptake and metabolism; 6-phospho-beta-glucosidase 1357827 celA 8111191 celA Streptococcus dysgalactiae subsp. equisimilis GGS_124 6-phospho-beta-glucosidase YP_002997116.1 1356388 R 486410 CDS YP_002997117.1 251782814 8112371 complement(1357929..1358861) 1 NC_012891.1 similar to protein of unknown function/lipoprotein [Streptococcus agalactiae 2603V/R]; lipoprotein 1358861 8112371 SDEG_1408 Streptococcus dysgalactiae subsp. equisimilis GGS_124 lipoprotein YP_002997117.1 1357929 R 486410 CDS YP_002997118.1 251782815 8111192 1359055..1359477 1 NC_012891.1 similar to phosphosugar-binding transcriptional regulator [Clostridium botulinum NCTC2916]; phosphosugar-binding transcriptionalregulator 1359477 8111192 SDEG_1409 Streptococcus dysgalactiae subsp. equisimilis GGS_124 phosphosugar-binding transcriptionalregulator YP_002997118.1 1359055 D 486410 CDS YP_002997119.1 251782816 8111193 complement(1359705..1360319) 1 NC_012891.1 similar to hypothetical protein SMU.1108c [Streptococcus mutans UA159]; hypothetical protein 1360319 8111193 SDEG_1410 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002997119.1 1359705 R 486410 CDS YP_002997120.1 251782817 8111194 complement(1360330..1361052) 1 NC_012891.1 similar to oxidoreductase [Lactobacillus plantarum WCFS1]; oxidoreductase 1361052 8111194 SDEG_1411 Streptococcus dysgalactiae subsp. equisimilis GGS_124 oxidoreductase YP_002997120.1 1360330 R 486410 CDS YP_002997121.1 251782818 8111195 complement(1361628..1363073) 1 NC_012891.1 similar to beta-glucosidase, [Streptococcus sanguinis SK36]; beta-glucosidas 1363073 bglA 8111195 bglA Streptococcus dysgalactiae subsp. equisimilis GGS_124 beta-glucosidas YP_002997121.1 1361628 R 486410 CDS YP_002997122.1 251782819 8112373 1363219..1364148 1 NC_012891.1 similar to hypothetical protein STRINF 01402 [Streptococcus infantarius subsp. infantarius ATCC BAA-102]; hypothetical protein 1364148 8112373 SDEG_1413 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002997122.1 1363219 D 486410 CDS YP_002997123.1 251782820 8111196 complement(1364223..1366136) 1 NC_012891.1 PTS system beta-glucoside-specific IIABC component [Streptococcus suis 89/1591]; similar to sugar-specific permease EIIA 1 domain; PTS system beta-glucoside-specific transporter subunit IIABC 1366136 8111196 SDEG_1414 Streptococcus dysgalactiae subsp. equisimilis GGS_124 PTS system beta-glucoside-specific transporter subunit IIABC YP_002997123.1 1364223 R 486410 CDS YP_002997124.1 251782821 8111197 complement(1366375..1367241) 1 NC_012891.1 similar to hypothetical protein STRINF 01404 [Streptococcus infantarius subsp. infantarius ATCC BAA-102]; hypothetical protein 1367241 8111197 SDEG_1415 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002997124.1 1366375 R 486410 CDS YP_002997125.1 251782822 8111198 complement(1367357..1368097) 1 NC_012891.1 similar to permease ATP-binding protein [Streptococcus gordonii str. Challis substr. CH1]; permease ATP-binding protein 1368097 8111198 SDEG_1416 Streptococcus dysgalactiae subsp. equisimilis GGS_124 permease ATP-binding protein YP_002997125.1 1367357 R 486410 CDS YP_002997126.1 251782823 8111199 1368408..1368833 1 NC_012891.1 similar to transposase IS861 orfB [Streptococcus equi subsp. zooepidemicus MGCS10565]; transposase IS861 orfB 1368833 8111199 SDEG_1417 Streptococcus dysgalactiae subsp. equisimilis GGS_124 transposase IS861 orfB YP_002997126.1 1368408 D 486410 CDS YP_002997127.1 251782824 8111200 complement(1368923..1370209) 1 NC_012891.1 similar to polysaccharide deacetylase family protein [Streptococcus pyogenes NZ131]; polysaccharide deacetylase 1370209 8111200 SDEG_1418 Streptococcus dysgalactiae subsp. equisimilis GGS_124 polysaccharide deacetylase YP_002997127.1 1368923 R 486410 CDS YP_002997128.1 251782825 8111201 complement(1370295..1371722) 1 NC_012891.1 similar to NADP-dependent glyceraldehyde-3-phosphate dehydrogenase [Streptococcus pyogenes MGAS5005]; NADP-dependent glyceraldehyde-3-phosphatedehydrogenase 1371722 gapN 8111201 gapN Streptococcus dysgalactiae subsp. equisimilis GGS_124 NADP-dependent glyceraldehyde-3-phosphatedehydrogenase YP_002997128.1 1370295 R 486410 CDS YP_002997129.1 251782826 8111985 complement(1371889..1373622) 1 NC_012891.1 similar to phosphoenolpyruvate-protein phosphotransferase [Streptococcus pyogenes MGAS5005]; phosphoenolpyruvate-protein phosphotransferase 1373622 pstI 8111985 pstI Streptococcus dysgalactiae subsp. equisimilis GGS_124 phosphoenolpyruvate-protein phosphotransferase YP_002997129.1 1371889 R 486410 CDS YP_002997130.1 251782827 8111319 complement(1373627..1373890) 1 NC_012891.1 similar to phosphocarrier protein HPr [Streptococcus pyogenes MGAS10394]; phosphocarrier protein HPr 1373890 ptsH 8111319 ptsH Streptococcus dysgalactiae subsp. equisimilis GGS_124 phosphocarrier protein HPr YP_002997130.1 1373627 R 486410 CDS YP_002997131.1 251782828 8111326 1374275..1374493 1 NC_012891.1 similar to glutaredoxin [Streptococcus pyogenes MGAS10394]; glutaredoxin 1374493 8111326 SDEG_1422 Streptococcus dysgalactiae subsp. equisimilis GGS_124 glutaredoxin YP_002997131.1 1374275 D 486410 CDS YP_002997132.1 251782829 8111202 1374513..1376672 1 NC_012891.1 Catalyzes the rate-limiting step in dNTP synthesis; ribonucleotide-diphosphate reductase subunit alpha 1376672 nrdE.2 8111202 nrdE.2 Streptococcus dysgalactiae subsp. equisimilis GGS_124 ribonucleotide-diphosphate reductase subunit alpha YP_002997132.1 1374513 D 486410 CDS YP_002997133.1 251782830 8111716 1377005..1377964 1 NC_012891.1 B2 or R2 protein; type 1b enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdE; ribonucleotide-diphosphate reductase subunit beta 1377964 nrdF 8111716 nrdF Streptococcus dysgalactiae subsp. equisimilis GGS_124 ribonucleotide-diphosphate reductase subunit beta YP_002997133.1 1377005 D 486410 CDS YP_002997134.1 251782831 8111718 1377942..1379300 1 NC_012891.1 similar to chloride channel protein [Streptococcus pyogenes MGAS10270]; chloride channel protein 1379300 8111718 SDEG_1425 Streptococcus dysgalactiae subsp. equisimilis GGS_124 chloride channel protein YP_002997134.1 1377942 D 486410 CDS YP_002997135.1 251782832 8111203 complement(1379335..1380030) 1 NC_012891.1 similar to CAAX amino terminal protease family [Streptococcus pyogenes MGAS5005]; CAAX amino terminal protease 1380030 8111203 SDEG_1426 Streptococcus dysgalactiae subsp. equisimilis GGS_124 CAAX amino terminal protease YP_002997135.1 1379335 R 486410 CDS YP_002997136.1 251782833 8111204 complement(1380049..1380810) 1 NC_012891.1 similar to hypothetical membrane spanning protein [Streptococcus pyogenes MGAS10394]; hypothetical protein 1380810 8111204 SDEG_1427 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002997136.1 1380049 R 486410 CDS YP_002997137.1 251782834 8111205 complement(1380807..1381022) 1 NC_012891.1 similar to transcriptional regulator Cro /CI family [Streptococcus pyogenes MGAS10394]; Cro/CI family transcriptional regulator 1381022 8111205 SDEG_1428 Streptococcus dysgalactiae subsp. equisimilis GGS_124 Cro/CI family transcriptional regulator YP_002997137.1 1380807 R 486410 CDS YP_002997138.1 251782835 8111206 complement(1381022..1381576) 1 NC_012891.1 similar to probable surface antigen negative regulator Par [Streptococcus suis 98HAH33]; surface antigen negative regulator 1381576 8111206 SDEG_1429 Streptococcus dysgalactiae subsp. equisimilis GGS_124 surface antigen negative regulator YP_002997138.1 1381022 R 486410 CDS YP_002997139.1 251782836 8111207 complement(1381736..1384354) 1 NC_012891.1 Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; alanyl-tRNA synthetase 1384354 alaS 8111207 alaS Streptococcus dysgalactiae subsp. equisimilis GGS_124 alanyl-tRNA synthetase YP_002997139.1 1381736 R 486410 CDS YP_002997140.1 251782837 8112319 complement(1384370..1384855) 1 NC_012891.1 similar to hypothetical protein SAK 0933 [Streptococcus agalactiae A909]; hypothetical protein 1384855 8112319 SDEG_1431 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002997140.1 1384370 R 486410 CDS YP_002997141.1 251782838 8111208 complement(1385110..1386177) 1 NC_012891.1 cis/trans isomerase of peptidylprolyl; PPIase; membrane-bound lipoprotein; foldase protein PrsA 1386177 prsA 8111208 prsA Streptococcus dysgalactiae subsp. equisimilis GGS_124 foldase protein PrsA YP_002997141.1 1385110 R 486410 CDS YP_002997142.1 251782839 8111314 complement(1386240..1386947) 1 NC_012891.1 similar to methyltransferase [Streptococcus pyogenes SSI-1]; methyltransferase 1386947 8111314 SDEG_1433 Streptococcus dysgalactiae subsp. equisimilis GGS_124 methyltransferase YP_002997142.1 1386240 R 486410 CDS YP_002997143.1 251782840 8111209 complement(1386999..1388210) 1 NC_012891.1 similar to oxalate formate antiporter [Streptococcus pyogenes SSI-1]; oxalate/formate antiporter 1388210 8111209 SDEG_1434 Streptococcus dysgalactiae subsp. equisimilis GGS_124 oxalate/formate antiporter YP_002997143.1 1386999 R 486410 CDS YP_002997144.1 251782841 8111210 complement(1388544..1389167) 1 NC_012891.1 similar to hydrolase haloacid dehalogenase-like family [Streptococcus equi subsp. zooepidemicus MGCS10565]; haloacid dehalogenase family hydrolase 1389167 8111210 SDEG_1435 Streptococcus dysgalactiae subsp. equisimilis GGS_124 haloacid dehalogenase family hydrolase YP_002997144.1 1388544 R 486410 CDS YP_002997145.1 251782842 8111211 complement(1389167..1389709) 1 NC_012891.1 similar to acetyltransferase GNAT family [Streptococcus equi subsp. zooepidemicus MGCS10565]; GNAT family acetyltransferase 1389709 8111211 SDEG_1436 Streptococcus dysgalactiae subsp. equisimilis GGS_124 GNAT family acetyltransferase YP_002997145.1 1389167 R 486410 CDS YP_002997146.1 251782843 8111212 complement(1389839..1390393) 1 NC_012891.1 similar to NADPH-dependent FMN reductase [Bacillus coagulans 36D1]; NADPH-dependent FMN reductase 1390393 8111212 SDEG_1437 Streptococcus dysgalactiae subsp. equisimilis GGS_124 NADPH-dependent FMN reductase YP_002997146.1 1389839 R 486410 CDS YP_002997147.1 251782844 8111213 complement(1390574..1392376) 1 NC_012891.1 similar to oligoendopeptidase F [Streptococcus pyogenes MGAS5005]; oligoendopeptidase F 1392376 pepB 8111213 pepB Streptococcus dysgalactiae subsp. equisimilis GGS_124 oligoendopeptidase F YP_002997147.1 1390574 R 486410 CDS YP_002997148.1 251782845 8111273 complement(1392387..1393346) 1 NC_012891.1 similar to competence protein/transcription factor [Streptococcus pyogenes MGAS10394]; competence protein/transcriptionfactor 1393346 8111273 SDEG_1439 Streptococcus dysgalactiae subsp. equisimilis GGS_124 competence protein/transcriptionfactor YP_002997148.1 1392387 R 486410 CDS YP_002997149.1 251782846 8111214 complement(1393461..1394378) 1 NC_012891.1 probable ORF of C-terminal portion of major facilitator family protein [Streptococcus agalactiae 2603V/R] resulted from mutation by unknown reason; major facilitator family protein 1394378 8111214 SDEG_1440 Streptococcus dysgalactiae subsp. equisimilis GGS_124 major facilitator family protein YP_002997149.1 1393461 R 486410 CDS YP_002997150.1 251782847 8111215 complement(1394369..1394620) 1 NC_012891.1 probable ORF of N-terminal portion of major facilitator family protein [Streptococcus agalactiae 2603V/R] resulted from mutation by unknown reason; major facilitator family protein 1394620 8111215 SDEG_1441 Streptococcus dysgalactiae subsp. equisimilis GGS_124 major facilitator family protein YP_002997150.1 1394369 R 486410 CDS YP_002997151.1 251782848 8111216 complement(1394712..1395428) 1 NC_012891.1 similar to 16S pseudouridylate synthetase [Streptococcus pyogenes MGAS8232]; 16S pseudouridylate synthetase 1395428 8111216 SDEG_1442 Streptococcus dysgalactiae subsp. equisimilis GGS_124 16S pseudouridylate synthetase YP_002997151.1 1394712 R 486410 CDS YP_002997152.1 251782849 8111217 complement(1395532..1396245) 1 NC_012891.1 similar to glucosamine-6-phosphate isomerase [Streptococcus pyogenes MGAS10394]; glucosamine-6-phosphate isomerase 1396245 nagB 8111217 nagB Streptococcus dysgalactiae subsp. equisimilis GGS_124 glucosamine-6-phosphate isomerase YP_002997152.1 1395532 R 486410 CDS YP_002997153.1 251782850 8111707 1396443..1397471 1 NC_012891.1 Synthesizes oQ from preQ1 in a single S-adenosylmethionine-requiring step; S-adenosylmethionine--tRNA ribosyltransferase-isomerase 1397471 queA 8111707 queA Streptococcus dysgalactiae subsp. equisimilis GGS_124 S-adenosylmethionine--tRNA ribosyltransferase-isomerase YP_002997153.1 1396443 D 486410 CDS YP_002997154.1 251782851 8111347 1397476..1398696 1 NC_012891.1 similar to hypothetical cytosolic protein [Streptococcus pyogenes MGAS10750]; hypothetical protein 1398696 8111347 SDEG_1445 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002997154.1 1397476 D 486410 CDS YP_002997155.1 251782852 8111218 complement(1398817..1399878) 1 NC_012891.1 similar to hypothetical protein SSA 0722 [Streptococcus sanguinis SK36]; hypothetical protein 1399878 8111218 SDEG_1446 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002997155.1 1398817 R 486410 CDS YP_002997156.1 251782853 8111219 complement(1400045..1400650) 1 NC_012891.1 similar to superoxide dismutase [Streptococcus pyogenes MGAS6180]; superoxide dismutase 1400650 sodA 8111219 sodA Streptococcus dysgalactiae subsp. equisimilis GGS_124 superoxide dismutase YP_002997156.1 1400045 R 486410 CDS YP_002997157.1 251782854 8110494 complement(1400747..1401787) 1 NC_012891.1 required for the assembly and function of the DNAX complex which is required for the assembly of the beta subunit onto primed DNA; DNA polymerase III subunit delta 1401787 holA 8110494 holA Streptococcus dysgalactiae subsp. equisimilis GGS_124 DNA polymerase III subunit delta YP_002997157.1 1400747 R 486410 CDS YP_002997158.1 251782855 8112034 complement(1401868..1404111) 1 NC_012891.1 similar to competence protein [Streptococcus pyogenes str. Manfredo]; competence protein 1404111 comEC 8112034 comEC Streptococcus dysgalactiae subsp. equisimilis GGS_124 competence protein YP_002997158.1 1401868 R 486410 CDS YP_002997159.1 251782856 8111634 complement(1404092..1404754) 1 NC_012891.1 similar to competence protein [Streptococcus pyogenes str. Manfredo]; competence protein 1404754 comEA 8111634 comEA Streptococcus dysgalactiae subsp. equisimilis GGS_124 competence protein YP_002997159.1 1404092 R 486410 CDS YP_002997160.1 251782857 8111632 complement(1405151..1405969) 1 NC_012891.1 similar to 1-acyl-sn-glycerol-3-phosphate acyltransferase [Streptococcus pyogenes MGAS10270]; 1-acyl-sn-glycerol-3-phosphate acyltransferase 1405969 8111632 SDEG_1451 Streptococcus dysgalactiae subsp. equisimilis GGS_124 1-acyl-sn-glycerol-3-phosphate acyltransferase YP_002997160.1 1405151 R 486410 CDS YP_002997161.1 251782858 8111220 1405931..1406785 1 NC_012891.1 similar to methyltransferase [Streptococcus pyogenes MGAS6180]; methyltransferase 1406785 8111220 SDEG_1452 Streptococcus dysgalactiae subsp. equisimilis GGS_124 methyltransferase YP_002997161.1 1405931 D 486410 CDS YP_002997162.1 251782859 8111221 1406775..1407053 1 NC_012891.1 similar to hypothetical protein with endo/excinuclease domain [Streptococcus pyogenes MGAS10394]; hypothetical protein 1407053 8111221 SDEG_1453 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002997162.1 1406775 D 486410 CDS YP_002997163.1 251782860 8111222 complement(1407077..1409077) 1 NC_012891.1 similar to Kup system potassium uptake protein [Streptococcus pyogenes MGAS10394]; Kup system potassium uptake protein 1409077 8111222 SDEG_1454 Streptococcus dysgalactiae subsp. equisimilis GGS_124 Kup system potassium uptake protein YP_002997163.1 1407077 R 486410 CDS YP_002997164.1 251782861 8111223 complement(1409205..1410824) 1 NC_012891.1 similar to ATP-dependent RNA helicase [Streptococcus pyogenes MGAS5005]; ATP-dependent RNA helicase 1410824 deaD 8111223 deaD Streptococcus dysgalactiae subsp. equisimilis GGS_124 ATP-dependent RNA helicase YP_002997164.1 1409205 R 486410 CDS YP_002997165.1 251782862 8111665 complement(1411053..1411883) 1 NC_012891.1 similar to YaeC family protein [Streptococcus agalactiae 2603V/R]; YaeC family protein 1411883 8111665 SDEG_1456 Streptococcus dysgalactiae subsp. equisimilis GGS_124 YaeC family protein YP_002997165.1 1411053 R 486410 CDS YP_002997166.1 251782863 8111224 complement(1411907..1412569) 1 NC_012891.1 similar to ABC transporter permease protein [Streptococcus agalactiae 2603V /R]; ABC transporter permease 1412569 8111224 SDEG_1457 Streptococcus dysgalactiae subsp. equisimilis GGS_124 ABC transporter permease YP_002997166.1 1411907 R 486410 CDS YP_002997167.1 251782864 8111225 complement(1412562..1413296) 1 NC_012891.1 similar to ABC transporter ATP-binding protein [Streptococcus agalactiae 2603V/R]; ABC transporter ATP-binding protein 1413296 8111225 SDEG_1458 Streptococcus dysgalactiae subsp. equisimilis GGS_124 ABC transporter ATP-binding protein YP_002997167.1 1412562 R 486410 CDS YP_002997168.1 251782865 8111226 complement(1413504..1413887) 1 NC_012891.1 similar to superfamily I DNA and RNA helicase [Streptococcus suis 98HAH33]; superfamily I DNA and RNA helicase 1413887 8111226 SDEG_1459 Streptococcus dysgalactiae subsp. equisimilis GGS_124 superfamily I DNA and RNA helicase YP_002997168.1 1413504 R 486410 CDS YP_002997169.1 251782866 8111227 complement(1414015..1415559) 1 NC_012891.1 stimulates the release of release factors 1 and 2 from the ribosome after hydrolysis of the ester bond in peptidyl-tRNA has occurred; GDP/GTP-binding protein; peptide chain release factor 3 1415559 prfC 8111227 prfC Streptococcus dysgalactiae subsp. equisimilis GGS_124 peptide chain release factor 3 YP_002997169.1 1414015 R 486410 CDS YP_002997170.1 251782867 8111307 complement(1415807..1416508) 1 NC_012891.1 similar to hypothetical membrane spanning protein [Streptococcus pyogenes MGAS5005]; hypothetical protein 1416508 8111307 SDEG_1461 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002997170.1 1415807 R 486410 CDS YP_002997171.1 251782868 8111228 complement(1416606..1417973) 1 NC_012891.1 similar to D-Ala-D-Ala adding enzyme [Streptococcus pyogenes MGAS315]; D-Ala-D-Ala adding enzyme 1417973 murF 8111228 murF Streptococcus dysgalactiae subsp. equisimilis GGS_124 D-Ala-D-Ala adding enzyme YP_002997171.1 1416606 R 486410 CDS YP_002997172.1 251782869 8111687 complement(1418179..1419225) 1 NC_012891.1 similar to D-alanylalanine synthetase [Streptococcus pyogenes M1 GAS]; D-alanyl-alanine synthetase A 1419225 ddl 8111687 ddl Streptococcus dysgalactiae subsp. equisimilis GGS_124 D-alanyl-alanine synthetase A YP_002997172.1 1418179 R 486410 CDS YP_002997173.1 251782870 8111663 complement(1419397..1419993) 1 NC_012891.1 involved in a recombinational process of DNA repair, independent of the recBC complex; recombination protein RecR 1419993 recR 8111663 recR Streptococcus dysgalactiae subsp. equisimilis GGS_124 recombination protein RecR YP_002997173.1 1419397 R 486410 CDS YP_002997174.1 251782871 8111038 complement(1420005..1422059) 1 NC_012891.1 similar to cell division protein FtsI [Streptococcus equi subsp. zooepidemicus MGCS10565]; cell division protein 1422059 ftsI 8111038 ftsI Streptococcus dysgalactiae subsp. equisimilis GGS_124 cell division protein YP_002997174.1 1420005 R 486410 CDS YP_002997175.1 251782872 8111917 complement(1422166..1422963) 1 NC_012891.1 similar to formate transporter [Streptococcus pyogenes MGAS10270]; formate transporter 1422963 8111917 SDEG_1466 Streptococcus dysgalactiae subsp. equisimilis GGS_124 formate transporter YP_002997175.1 1422166 R 486410 CDS YP_002997176.1 251782873 8111229 complement(1423063..1423605) 1 NC_012891.1 similar to hypothetical protein SPy 1425 [Streptococcus pyogenes M1 GAS]; hypothetical protein 1423605 8111229 SDEG_1467 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002997176.1 1423063 R 486410 CDS YP_002997177.1 251782874 8111230 complement(1423707..1424228) 1 NC_012891.1 similar to transcriptional regulator [Streptococcus pyogenes M1 GAS]; transcriptional regulator 1424228 8111230 SDEG_1468 Streptococcus dysgalactiae subsp. equisimilis GGS_124 transcriptional regulator YP_002997177.1 1423707 R 486410 CDS YP_002997178.1 251782875 8111231 complement(1424338..1425033) 1 NC_012891.1 2,3-bisphosphoglycerate-dependent; catalyzes the interconversion of 2-phosphoglycerate to 3-phosphoglycerate; phosphoglyceromutase 1425033 gpmA 8111231 gpmA Streptococcus dysgalactiae subsp. equisimilis GGS_124 phosphoglyceromutase YP_002997178.1 1424338 R 486410 CDS YP_002997179.1 251782876 8111232 complement(1425243..1426271) 1 NC_012891.1 similar to transposase [Streptococcus pyogenes MGAS10270]; transposase 1426271 8111232 SDEG_1470 Streptococcus dysgalactiae subsp. equisimilis GGS_124 transposase YP_002997179.1 1425243 R 486410 CDS YP_002997180.1 251782877 8111233 1426437..1427384 1 NC_012891.1 catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway; subclass 1A is a dimer formed by two identical PyrD subunits each containing an FMN group; dihydroorotate dehydrogenase 1A 1427384 pyrD 8111233 pyrD Streptococcus dysgalactiae subsp. equisimilis GGS_124 dihydroorotate dehydrogenase 1A YP_002997180.1 1426437 D 486410 CDS YP_002997181.1 251782878 8111340 complement(1427442..1427615) 1 NC_012891.1 similar to hypothetical protein M6 Spy1192 [Streptococcus pyogenes MGAS10394]; hypothetical protein 1427615 8111340 SDEG_1472 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002997181.1 1427442 R 486410 CDS YP_002997182.1 251782879 8111234 complement(1427687..1429549) 1 NC_012891.1 similar to heavy metal-transporting ATPase [Streptococcus pyogenes M1 GAS]; heavy metal-transporting ATPase 1429549 8111234 SDEG_1473 Streptococcus dysgalactiae subsp. equisimilis GGS_124 heavy metal-transporting ATPase YP_002997182.1 1427687 R 486410 CDS YP_002997183.1 251782880 8111235 1429753..1430625 1 NC_012891.1 similar to positive transcriptional regulator MutR family [Streptococcus equi subsp. zooepidemicus MGCS10565]; positive transcriptional regulator MutR family 1430625 8111235 SDEG_1474 Streptococcus dysgalactiae subsp. equisimilis GGS_124 positive transcriptional regulator MutR family YP_002997183.1 1429753 D 486410 CDS YP_002997184.1 251782881 8111236 1430695..1431885 1 NC_012891.1 similar to transporter probable SP1116 [Streptococcus gordonii str. Challis substr. CH1]; transporter 1431885 8111236 SDEG_1475 Streptococcus dysgalactiae subsp. equisimilis GGS_124 transporter YP_002997184.1 1430695 D 486410 CDS YP_002997185.1 251782882 8111237 complement(1432081..1432356) 1 NC_012891.1 similar to DNA-binding protein HU [Streptococcus pyogenes MGAS10394]; DNA-binding protein HU 1432356 8111237 SDEG_1476 Streptococcus dysgalactiae subsp. equisimilis GGS_124 DNA-binding protein HU YP_002997185.1 1432081 R 486410 CDS YP_002997186.1 251782883 8111238 complement(1432455..1433042) 1 NC_012891.1 similar to hypothetical protein SPy 1491 [Streptococcus pyogenes M1 GAS]; hypothetical protein 1433042 8111238 SDEG_1477 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002997186.1 1432455 R 486410 CDS YP_002997187.1 251782884 8111239 complement(1433020..1433892) 1 NC_012891.1 similar to Lipase /Acylhydrolase with GDSL-like motif [Streptococcus pyogenes MGAS10750]; lipase/acylhydrolase with GDSL-like motif 1433892 8111239 SDEG_1478 Streptococcus dysgalactiae subsp. equisimilis GGS_124 lipase/acylhydrolase with GDSL-like motif YP_002997187.1 1433020 R 486410 CDS YP_002997188.1 251782885 8111240 complement(1433855..1434706) 1 NC_012891.1 similar to DegV family protein [Streptococcus pyogenes MGAS10394]; DegV family fatty acid binding protein 1434706 8111240 SDEG_1479 Streptococcus dysgalactiae subsp. equisimilis GGS_124 DegV family fatty acid binding protein YP_002997188.1 1433855 R 486410 CDS YP_002997189.1 251782886 8111241 complement(1434935..1435831) 1 NC_012891.1 similar to hypothetical protein M28 Spy1166 [Streptococcus pyogenes MGAS6180]; hypothetical protein 1435831 8111241 SDEG_1480 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002997189.1 1434935 R 486410 CDS YP_002997190.1 251782887 8111242 complement(1436038..1437702) 1 NC_012891.1 similar to RecN [Streptococcus pyogenes MGAS10394]; DNA repair protein 1437702 recN 8111242 recN Streptococcus dysgalactiae subsp. equisimilis GGS_124 DNA repair protein YP_002997190.1 1436038 R 486410 CDS YP_002997191.1 251782888 8111036 complement(1437718..1438221) 1 NC_012891.1 similar to arginine repressor argR [Streptococcus pyogenes MGAS10750]; arginine repressor 1438221 argR1 8111036 argR1 Streptococcus dysgalactiae subsp. equisimilis GGS_124 arginine repressor YP_002997191.1 1437718 R 486410 CDS YP_002997192.1 251782889 8112335 complement(1438175..1439002) 1 NC_012891.1 similar to hemolysin [Streptococcus pyogenes MGAS5005]; hemolysin 1439002 8112335 SDEG_1483 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hemolysin YP_002997192.1 1438175 R 486410 CDS YP_002997193.1 251782890 8111243 complement(1438995..1439867) 1 NC_012891.1 similar to dimethylallyltransferase/ geranyltranstransferase [Streptococcus pyogenes MGAS5005]; trans-Isoprenyl Diphosphate Synthases (trans IPPS)head-to-tail (HT) (1'-4) condensation reactions; cd00685; dimethylallyltransferase/ geranyltranstransferase 1439867 fps 8111243 fps Streptococcus dysgalactiae subsp. equisimilis GGS_124 dimethylallyltransferase/ geranyltranstransferase YP_002997193.1 1438995 R 486410 CDS YP_002997194.1 251782891 8111908 complement(1439867..1440082) 1 NC_012891.1 catalyzes the bidirectional exonucleolytic cleavage of DNA; exodeoxyribonuclease VII small subunit 1440082 xseB 8111908 xseB Streptococcus dysgalactiae subsp. equisimilis GGS_124 exodeoxyribonuclease VII small subunit YP_002997194.1 1439867 R 486410 CDS YP_002997195.1 251782892 8111955 complement(1440060..1441400) 1 NC_012891.1 bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides; exodeoxyribonuclease VII large subunit 1441400 xseA 8111955 xseA Streptococcus dysgalactiae subsp. equisimilis GGS_124 exodeoxyribonuclease VII large subunit YP_002997195.1 1440060 R 486410 CDS YP_002997196.1 251782893 8111954 complement(1441551..1442396) 1 NC_012891.1 similar to sugar kinase [Streptococcus equi subsp. zooepidemicus MGCS10565]; sugar kinase 1442396 8111954 SDEG_1487 Streptococcus dysgalactiae subsp. equisimilis GGS_124 sugar kinase YP_002997196.1 1441551 R 486410 CDS YP_002997197.1 251782894 8111244 complement(1442393..1443247) 1 NC_012891.1 catalyzes the formation of 5,10-methenyltetrahydrofolate from 5,10-methylenetetrahydrofolate and subsequent formation of 10-formyltetrahydrofolate from 5,10-methenyltetrahydrofolate; bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase 1443247 8111244 SDEG_1488 Streptococcus dysgalactiae subsp. equisimilis GGS_124 bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase YP_002997197.1 1442393 R 486410 CDS YP_002997198.1 251782895 8111245 complement(1443420..1445114) 1 NC_012891.1 similar to phosphoglucomutase [Streptococcus pyogenes MGAS5005]; phosphoglucomutase 1445114 8111245 SDEG_1489 Streptococcus dysgalactiae subsp. equisimilis GGS_124 phosphoglucomutase YP_002997198.1 1443420 R 486410 CDS YP_002997199.1 251782896 8111246 complement(1445267..1446691) 1 NC_012891.1 similar to deoxyribodipyrimidine photolyase [Streptococcus pyogenes MGAS5005]; deoxyribodipyrimidine photolyase 1446691 phr 8111246 phr Streptococcus dysgalactiae subsp. equisimilis GGS_124 deoxyribodipyrimidine photolyase YP_002997199.1 1445267 R 486410 CDS YP_002997200.1 251782897 8111295 complement(1446884..1447033) 1 NC_012891.1 similar to hypothetical protein SMU.571 [Streptococcus mutans UA159]; hypothetical protein 1447033 8111295 SDEG_1491 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002997200.1 1446884 R 486410 CDS YP_002997201.1 251782898 8111247 complement(1447033..1449192) 1 NC_012891.1 similar to ferrous ion transport protein B [Streptococcus mutans UA159]; ferrous ion transport protein B 1449192 feoB 8111247 feoB Streptococcus dysgalactiae subsp. equisimilis GGS_124 ferrous ion transport protein B YP_002997201.1 1447033 R 486410 CDS YP_002997202.1 251782899 8111888 complement(1449189..1449668) 1 NC_012891.1 similar to ferrous ion transport protein A [Streptococcus mutans UA159]; ferrous ion transport protein A 1449668 feoA 8111888 feoA Streptococcus dysgalactiae subsp. equisimilis GGS_124 ferrous ion transport protein A YP_002997202.1 1449189 R 486410 CDS YP_002997203.1 251782900 8111887 complement(1449866..1450600) 1 NC_012891.1 similar to amino acid transport ATP-binding protein [Streptococcus pyogenes MGAS10394]; amino acid transport ATP-binding protein 1450600 artP 8111887 artP Streptococcus dysgalactiae subsp. equisimilis GGS_124 amino acid transport ATP-binding protein YP_002997203.1 1449866 R 486410 CDS YP_002997204.1 251782901 8112345 complement(1450600..1451286) 1 NC_012891.1 similar to arginine transport system permease protein [Streptococcus pyogenes MGAS5005]; arginine transport system permease 1451286 artQ 8112345 artQ Streptococcus dysgalactiae subsp. equisimilis GGS_124 arginine transport system permease YP_002997204.1 1450600 R 486410 CDS YP_002997205.1 251782902 8112346 1451942..1454233 1 NC_012891.1 similar to ATP-dependent endopeptidase clp ATP-binding subunit clpE [Streptococcus pyogenes MGAS2096]; ATP-dependent endopeptidase clp ATP-binding subunit 1454233 clpE 8112346 clpE Streptococcus dysgalactiae subsp. equisimilis GGS_124 ATP-dependent endopeptidase clp ATP-binding subunit YP_002997205.1 1451942 D 486410 CDS YP_002997206.1 251782903 8111622 1454351..1454806 1 NC_012891.1 7,8-dihydro-8-oxoguanine-triphosphatase; similar to mutator protein (78-dihydro-8-oxoguanine-triphosphatase) [Streptococcus pyogenes MGAS6180]; mutator protein 1454806 mutT 8111622 mutT Streptococcus dysgalactiae subsp. equisimilis GGS_124 mutator protein YP_002997206.1 1454351 D 486410 CDS YP_002997207.1 251782904 8111697 1454856..1455158 1 NC_012891.1 similar to hypothetical cytosolic protein [Streptococcus pyogenes MGAS10394]; hypothetical protein 1455158 8111697 SDEG_1498 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002997207.1 1454856 D 486410 CDS YP_002997208.1 251782905 8111248 complement(1455560..1458361) 1 NC_012891.1 IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase family; some organisms carry two different copies of this enzyme; isoleucyl-tRNA synthetase 1458361 ileS 8111248 ileS Streptococcus dysgalactiae subsp. equisimilis GGS_124 isoleucyl-tRNA synthetase YP_002997208.1 1455560 R 486410 CDS YP_002997209.1 251782906 8112050 complement(1458627..1459382) 1 NC_012891.1 similar to cell division initiation protein DivIVA [Streptococcus pyogenes MGAS6180]; cell division initiation protein DivIVA 1459382 divIVAS 8112050 divIVAS Streptococcus dysgalactiae subsp. equisimilis GGS_124 cell division initiation protein DivIVA YP_002997209.1 1458627 R 486410 CDS YP_002997210.1 251782907 8111675 complement(1459392..1460183) 1 NC_012891.1 similar to hypothetical protein SpyM50607 [Streptococcus pyogenes str. Manfredo]; hypothetical protein 1460183 8111675 SDEG_1501 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002997210.1 1459392 R 486410 CDS YP_002997211.1 251782908 8111249 complement(1460183..1460437) 1 NC_012891.1 similar to hypothetical protein SpyM50606 [Streptococcus pyogenes str. Manfredo]; hypothetical protein 1460437 8111249 SDEG_1502 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002997211.1 1460183 R 486410 CDS YP_002997212.1 251782909 8111250 complement(1460443..1461114) 1 NC_012891.1 similar to hypothetical cytosolic protein [Streptococcus pyogenes MGAS10750]; hypothetical protein 1461114 8111250 SDEG_1503 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002997212.1 1460443 R 486410 CDS YP_002997213.1 251782910 8111251 complement(1461115..1461786) 1 NC_012891.1 similar to pyridoxaL 5'-phosphate dependent enzyme class III family [Streptococcus equi subsp. zooepidemicus MGCS10565]; pyridoxaL 5'-phosphate dependent enzyme classIII family 1461786 8111251 SDEG_1504 Streptococcus dysgalactiae subsp. equisimilis GGS_124 pyridoxaL 5'-phosphate dependent enzyme classIII family YP_002997213.1 1461115 R 486410 CDS YP_002997214.1 251782911 8111252 complement(1461789..1463108) 1 NC_012891.1 GTPase; similar structure to tubulin; forms ring-shaped polymers at the site of cell division; other proteins such as FtsA, ZipA, and ZapA, interact with and regulate FtsZ function; cell division protein FtsZ 1463108 ftsZ 8111252 ftsZ Streptococcus dysgalactiae subsp. equisimilis GGS_124 cell division protein FtsZ YP_002997214.1 1461789 R 486410 CDS YP_002997215.1 251782912 8111979 complement(1463132..1464496) 1 NC_012891.1 similar to cell division protein [Streptococcus pyogenes MGAS5005]; cell division protein 1464496 ftsA 8111979 ftsA Streptococcus dysgalactiae subsp. equisimilis GGS_124 cell division protein YP_002997215.1 1463132 R 486410 CDS YP_002997216.1 251782913 8111914 complement(1464707..1465675) 1 NC_012891.1 probable ORF of C-terminal portion of cell division protein [Streptococcus pyogenes MGAS8232] resulted from mutation by unknown reason; cell division protein 1465675 ftsQ 8111914 ftsQ Streptococcus dysgalactiae subsp. equisimilis GGS_124 cell division protein YP_002997216.1 1464707 R 486410 CDS YP_002997217.1 251782914 8111974 complement(1465488..1465856) 1 NC_012891.1 probable ORF of N-terminal portion of cell division protein [Streptococcus pyogenes MGAS8232] resulted from mutation by unknown reason; cell division protein 1465856 ftsQ 8111974 ftsQ Streptococcus dysgalactiae subsp. equisimilis GGS_124 cell division protein YP_002997217.1 1465488 R 486410 CDS YP_002997218.1 251782915 8111975 complement(1465857..1466939) 1 NC_012891.1 UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; involved in cell wall formation; inner membrane-associated; last step of peptidoglycan synthesis; UDP diphospho-muramoyl pentapeptide beta-N acetylglucosaminyl transferase 1466939 murG 8111975 murG Streptococcus dysgalactiae subsp. equisimilis GGS_124 UDP diphospho-muramoyl pentapeptide beta-N acetylglucosaminyl transferase YP_002997218.1 1465857 R 486410 CDS YP_002997219.1 251782916 8111688 complement(1466939..1468309) 1 NC_012891.1 UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase 1468309 murD 8111688 murD Streptococcus dysgalactiae subsp. equisimilis GGS_124 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase YP_002997219.1 1466939 R 486410 CDS YP_002997220.1 251782917 8111685 complement(1468544..1470181) 1 NC_012891.1 similar to hypothetical protein [Streptococcus suis]; hypothetical protein 1470181 8111685 SDEG_1511 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002997220.1 1468544 R 486410 CDS YP_002997221.1 251782918 8111253 complement(1470434..1470691) 1 NC_012891.1 similar to hypothetical protein Sez 0590 [Streptococcus equi subsp. zooepidemicus MGCS10565]; hypothetical protein 1470691 8111253 SDEG_1512 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002997221.1 1470434 R 486410 CDS YP_002997222.1 251782919 8111254 complement(1470790..1472631) 1 NC_012891.1 similar to GTP-binding protein [Streptococcus pyogenes MGAS5005]; GTP-binding protein 1472631 typA 8111254 typA Streptococcus dysgalactiae subsp. equisimilis GGS_124 GTP-binding protein YP_002997222.1 1470790 R 486410 CDS YP_002997223.1 251782920 8111936 complement(1472813..1473202) 1 NC_012891.1 similar to rhodanese-related sulfurtransferase [Streptococcus pyogenes MGAS5005]; rhodanese-related sulfurtransferase 1473202 8111936 SDEG_1514 Streptococcus dysgalactiae subsp. equisimilis GGS_124 rhodanese-related sulfurtransferase YP_002997223.1 1472813 R 486410 CDS YP_002997224.1 251782921 8111255 complement(1473212..1474183) 1 NC_012891.1 similar to glucokinase/xylose repressor [Streptococcus pyogenes MGAS5005]; glucokinase/xylose repressor 1474183 glcK 8111255 glcK Streptococcus dysgalactiae subsp. equisimilis GGS_124 glucokinase/xylose repressor YP_002997224.1 1473212 R 486410 CDS YP_002997225.1 251782922 8111994 complement(1474188..1474409) 1 NC_012891.1 similar to hypothetical cytosolic protein [Streptococcus pyogenes MGAS10394]; hypothetical protein 1474409 8111994 SDEG_1516 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002997225.1 1474188 R 486410 CDS YP_002997226.1 251782923 8111256 complement(1474533..1475060) 1 NC_012891.1 similar to ferroxidase [Streptococcus pyogenes MGAS10394]; ferroxidase 1475060 8111256 SDEG_1517 Streptococcus dysgalactiae subsp. equisimilis GGS_124 ferroxidase YP_002997226.1 1474533 R 486410 CDS YP_002997227.1 251782924 8111257 1475279..1475914 1 NC_012891.1 similar to prepilin peptidase family [Streptococcus pyogenes MGAS6180]; prepilin peptidase family 1475914 8111257 SDEG_1518 Streptococcus dysgalactiae subsp. equisimilis GGS_124 prepilin peptidase family YP_002997227.1 1475279 D 486410 CDS YP_002997228.1 251782925 8111258 complement(1475957..1476553) 1 NC_012891.1 similar to TCS response regulator [Streptococcus equi subsp. zooepidemicus MGCS10565]; two-component system response regulator 1476553 8111258 SDEG_1519 Streptococcus dysgalactiae subsp. equisimilis GGS_124 two-component system response regulator YP_002997228.1 1475957 R 486410 CDS YP_002997229.1 251782926 8111259 complement(1476534..1477640) 1 NC_012891.1 similar to TCS sensor histidine kinase [Streptococcus equi subsp. zooepidemicus MGCS10565]; two-component system sensor histidine kinase 1477640 8111259 SDEG_1520 Streptococcus dysgalactiae subsp. equisimilis GGS_124 two-component system sensor histidine kinase YP_002997229.1 1476534 R 486410 CDS YP_002997230.1 251782927 8111260 complement(1477640..1478365) 1 NC_012891.1 similar to ABC transporter permease protein [Streptococcus equi subsp. zooepidemicus MGCS10565]; ABC transporter permease 1478365 8111260 SDEG_1521 Streptococcus dysgalactiae subsp. equisimilis GGS_124 ABC transporter permease YP_002997230.1 1477640 R 486410 CDS YP_002997231.1 251782928 8111261 complement(1478369..1479256) 1 NC_012891.1 similar to multi drug transpot ATP-binding protein [Streptococcus equi subsp.; multi drug transpot ATP-binding protein 1479256 8111261 SDEG_1522 Streptococcus dysgalactiae subsp. equisimilis GGS_124 multi drug transpot ATP-binding protein YP_002997231.1 1478369 R 486410 CDS YP_002997232.1 251782929 8111262 complement(1479395..1481131) 1 NC_012891.1 similar to hypothetical protein gbs0508 [Streptococcus agalactiae NEM316]; hypothetical protein 1481131 8111262 SDEG_1523 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002997232.1 1479395 R 486410 CDS YP_002997233.1 251782930 8111263 complement(1481118..1481504) 1 NC_012891.1 similar to ABC transporter ATP-binding/permease protein [Streptococcus pneumoniae D39]; ABC transporter ATP-binding protein/permease 1481504 8111263 SDEG_1524 Streptococcus dysgalactiae subsp. equisimilis GGS_124 ABC transporter ATP-binding protein/permease YP_002997233.1 1481118 R 486410 CDS YP_002997234.1 251782931 8111264 complement(1481569..1482864) 1 NC_012891.1 similar to ABC transporter ATP-binding/permease protein [Streptococcus agalactiae A909]; ABC transporter ATP-binding protein/permease 1482864 8111264 SDEG_1525 Streptococcus dysgalactiae subsp. equisimilis GGS_124 ABC transporter ATP-binding protein/permease YP_002997234.1 1481569 R 486410 CDS YP_002997235.1 251782932 8111265 complement(1482959..1483474) 1 NC_012891.1 similar to VanZF domain protein [Streptococcus agalactiae COH1]; VanZF domain-containing protein 1483474 8111265 SDEG_1526 Streptococcus dysgalactiae subsp. equisimilis GGS_124 VanZF domain-containing protein YP_002997235.1 1482959 R 486410 CDS YP_002997236.1 251782933 8111266 complement(1483479..1484561) 1 NC_012891.1 23S rRNA m2A2503 methyltransferase; methylates the C2 position of the A2530 nucleotide in 23S rRNA; may be involved in antibiotic resistance; ribosomal RNA large subunit methyltransferase N 1484561 8111266 SDEG_1527 Streptococcus dysgalactiae subsp. equisimilis GGS_124 ribosomal RNA large subunit methyltransferase N YP_002997236.1 1483479 R 486410 CDS YP_002997237.1 251782934 8111267 complement(1484565..1485179) 1 NC_012891.1 similar to transcriptional regulator [Streptococcus pyogenes MGAS5005]; transcriptional regulator 1485179 8111267 SDEG_1528 Streptococcus dysgalactiae subsp. equisimilis GGS_124 transcriptional regulator YP_002997237.1 1484565 R 486410 CDS YP_002997238.1 251782935 8111268 complement(1485438..1485845) 1 NC_012891.1 probable ORF of C-terminal portion of hypothetical protein SMU.796 [Streptococcus mutans UA159] resulted from mutation by unknown reason; hypothetical protein 1485845 8111268 SDEG_1529 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002997238.1 1485438 R 486410 CDS YP_002997239.1 251782936 8111269 complement(1485860..1486189) 1 NC_012891.1 probable ORF of N-terminal portion of hypothetical protein SMU.796 [Streptococcus mutans UA159] resulted from mutation by unknown reason; hypothetical protein 1486189 8111269 SDEG_1530 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002997239.1 1485860 R 486410 CDS YP_002997240.1 251782937 8111270 1486583..1487230 1 NC_012891.1 similar to hypothetical protein CLONEX 04238 [Clostridium nexile DSM 1787]; hypothetical protein 1487230 8111270 SDEG_1531 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002997240.1 1486583 D 486410 CDS YP_002997241.1 251782938 8111271 1487295..1487726 1 NC_012891.1 similar to transposase [Streptococcus pneumoniae SP9-BS68]; transposase 1487726 8111271 SDEG_1532 Streptococcus dysgalactiae subsp. equisimilis GGS_124 transposase YP_002997241.1 1487295 D 486410 CDS YP_002997242.1 251782939 8111272 complement(1488036..1488815) 1 NC_012891.1 similar to D-ribose-binding protein precursor RbsB [Streptococcus equi subsp.; D-ribose-binding protein 1488815 rbsB 8111272 rbsB Streptococcus dysgalactiae subsp. equisimilis GGS_124 D-ribose-binding protein YP_002997242.1 1488036 R 486410 CDS YP_002997243.1 251782940 8111352 complement(1488812..1489195) 1 NC_012891.1 similar to ribose transport ATP-binding protein RbsA [Streptococcus equi subsp. zooepidemicus MGCS10565]; ribose transport ATP-binding protein 1489195 rbsA 8111352 rbsA Streptococcus dysgalactiae subsp. equisimilis GGS_124 ribose transport ATP-binding protein YP_002997243.1 1488812 R 486410 CDS YP_002997244.1 251782941 8111351 complement(1489211..1489609) 1 NC_012891.1 cytoplasmic mutarotase that catalyzes the conversion between beta-pyran and beta-furan forms of D-ribose; RbsD is required for efficient ribose utilization in E. coli; rbsD-mutant E. coli strains are unable to use ribose as a sole carbon source; D-ribose pyranase 1489609 rbsD 8111351 rbsD Streptococcus dysgalactiae subsp. equisimilis GGS_124 D-ribose pyranase YP_002997244.1 1489211 R 486410 CDS YP_002997245.1 251782942 8111353 complement(1489584..1490495) 1 NC_012891.1 similar to ribokinase RbsK [Streptococcus equi subsp. zooepidemicus MGCS10565]; ribokinase 1490495 rbsK 8111353 rbsK Streptococcus dysgalactiae subsp. equisimilis GGS_124 ribokinase YP_002997245.1 1489584 R 486410 CDS YP_002997246.1 251782943 8111030 complement(1490488..1491471) 1 NC_012891.1 similar to ribose transport operon repressor [Streptococcus pyogenes MGAS315]; ribose transport operon repressor 1491471 8111030 SDEG_1537 Streptococcus dysgalactiae subsp. equisimilis GGS_124 ribose transport operon repressor YP_002997246.1 1490488 R 486410 CDS YP_002997247.1 251782944 8112136 complement(1491752..1492789) 1 NC_012891.1 similar to ATP-dependent endopeptidase Lon [Streptococcus pyogenes MGAS10270]; ATP-dependent endopeptidase 1492789 8112136 SDEG_1538 Streptococcus dysgalactiae subsp. equisimilis GGS_124 ATP-dependent endopeptidase YP_002997247.1 1491752 R 486410 CDS YP_002997248.1 251782945 8112137 complement(1492776..1493267) 1 NC_012891.1 Catalyzes the conversion of ATP and pantetheine 4'-phosphate to diphosphate and 3'-dephospho-coA; phosphopantetheine adenylyltransferase 1493267 coaD 8112137 coaD Streptococcus dysgalactiae subsp. equisimilis GGS_124 phosphopantetheine adenylyltransferase YP_002997248.1 1492776 R 486410 CDS YP_002997249.1 251782946 8111630 complement(1493257..1493805) 1 NC_012891.1 similar to type II DNA modification methyltransferase [Streptococcus pyogenes MGAS315]; type II DNA modification methyltransferase 1493805 8111630 SDEG_1540 Streptococcus dysgalactiae subsp. equisimilis GGS_124 type II DNA modification methyltransferase YP_002997249.1 1493257 R 486410 CDS YP_002997250.1 251782947 8112138 complement(1493990..1494982) 1 NC_012891.1 catalyzes the formation of asparagine from aspartate and ammonia; asparagine synthetase AsnA 1494982 asnA 8112138 asnA Streptococcus dysgalactiae subsp. equisimilis GGS_124 asparagine synthetase AsnA YP_002997250.1 1493990 R 486410 CDS YP_002997251.1 251782948 8112348 complement(1495309..1496259) 1 NC_012891.1 catalyzes the reversible synthesis of carbamate and ATP from carbamoyl phosphate and ADP; carbamate kinase 1496259 arcC 8112348 arcC Streptococcus dysgalactiae subsp. equisimilis GGS_124 carbamate kinase YP_002997251.1 1495309 R 486410 CDS YP_002997252.1 251782949 8112333 1496749..1497705 1 NC_012891.1 similar to transposase [Streptococcus pneumoniae SP9-BS68]; transposase 1497705 8112333 SDEG_1543 Streptococcus dysgalactiae subsp. equisimilis GGS_124 transposase YP_002997252.1 1496749 D 486410 CDS YP_002997253.1 251782950 8112139 complement(1497893..1499224) 1 NC_012891.1 similar to hypothetical protein M5005 Spy 1271 [Streptococcus pyogenes MGAS5005]; hypothetical protein 1499224 8112139 SDEG_1544 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002997253.1 1497893 R 486410 CDS YP_002997254.1 251782951 8112140 complement(1499241..1500791) 1 NC_012891.1 similar to arginine/ornithine antiporter [Streptococcus pyogenes MGAS5005]; arginine/ornithine antiporter 1500791 8112140 SDEG_1545 Streptococcus dysgalactiae subsp. equisimilis GGS_124 arginine/ornithine antiporter YP_002997254.1 1499241 R 486410 CDS YP_002997255.1 251782952 8112141 complement(1500904..1501917) 1 NC_012891.1 catalyzes the formation of ornithine and carbamylphosphate from citrulline in the arginine catabolic pathway; ornithine carbamoyltransferase 1501917 arcB 8112141 arcB Streptococcus dysgalactiae subsp. equisimilis GGS_124 ornithine carbamoyltransferase YP_002997255.1 1500904 R 486410 CDS YP_002997256.1 251782953 8112332 complement(1502041..1502382) 1 NC_012891.1 similar to COG0454, Histone acetyltransferase HPA2 and related acetyltransferases [Streptococcus pyogenes M49 591]; histone acetyltransferase HPA2-like protein 1502382 8112332 SDEG_1547 Streptococcus dysgalactiae subsp. equisimilis GGS_124 histone acetyltransferase HPA2-like protein YP_002997256.1 1502041 R 486410 CDS YP_002997257.1 251782954 8112142 complement(1502482..1503717) 1 NC_012891.1 catalyzes the degradation of arginine to citruline and ammonia; arginine deiminase 1503717 arcA 8112142 arcA Streptococcus dysgalactiae subsp. equisimilis GGS_124 arginine deiminase YP_002997257.1 1502482 R 486410 CDS YP_002997258.1 251782955 8112331 complement(1503993..1504673) 1 NC_012891.1 similar to transcription regulator crp family [Streptococcus pyogenes MGAS10394]; Crp family transcriptional regulator 1504673 8112331 SDEG_1549 Streptococcus dysgalactiae subsp. equisimilis GGS_124 Crp family transcriptional regulator YP_002997258.1 1503993 R 486410 CDS YP_002997259.1 251782956 8112143 1504815..1505288 1 NC_012891.1 similar to arginine repressor argR [Streptococcus pyogenes MGAS10394]; arginine repressor 1505288 argR 8112143 argR Streptococcus dysgalactiae subsp. equisimilis GGS_124 arginine repressor YP_002997259.1 1504815 D 486410 CDS YP_002997260.1 251782957 8112334 complement(1505466..1506182) 1 NC_012891.1 similar to hypothetical protein M28 Spy1216 [Streptococcus pyogenes MGAS6180]; hypothetical protein 1506182 8112334 SDEG_1551 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002997260.1 1505466 R 486410 CDS YP_002997261.1 251782958 8112144 complement(1506196..1507275) 1 NC_012891.1 similar to hypothetical cytosolic protein [Streptococcus pyogenes MGAS5005]; hypothetical protein 1507275 8112144 SDEG_1552 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002997261.1 1506196 R 486410 CDS YP_002997262.1 251782959 8112145 complement(1507348..1509081) 1 NC_012891.1 similar to two-component sensor kinase [Streptococcus pyogenes MGAS5005]; two-component sensor kinase 1509081 yesM 8112145 yesM Streptococcus dysgalactiae subsp. equisimilis GGS_124 two-component sensor kinase YP_002997262.1 1507348 R 486410 CDS YP_002997263.1 251782960 8111961 complement(1509078..1509818) 1 NC_012891.1 similar to two-component response regulator YesN [Streptococcus pyogenes MGAS10394]; two-component response regulator 1509818 yesN 8111961 yesN Streptococcus dysgalactiae subsp. equisimilis GGS_124 two-component response regulator YP_002997263.1 1509078 R 486410 CDS YP_002997264.1 251782961 8111964 complement(1509906..1511012) 1 NC_012891.1 similar to bifunctional methionine sulfoxide reductase A/B protein [Streptococcus pyogenes MGAS6180]; bifunctional methionine sulfoxide reductase A/B 1511012 msrA 8111964 msrA Streptococcus dysgalactiae subsp. equisimilis GGS_124 bifunctional methionine sulfoxide reductase A/B YP_002997264.1 1509906 R 486410 CDS YP_002997265.1 251782962 8110944 complement(1511055..1511648) 1 NC_012891.1 similar to thiol:disulfide interchange protein [Streptococcus pyogenes MGAS5005]; disulfide interchange protein 1511648 tipA 8110944 tipA Streptococcus dysgalactiae subsp. equisimilis GGS_124 disulfide interchange protein YP_002997265.1 1511055 R 486410 CDS YP_002997266.1 251782963 8110524 complement(1511690..1512400) 1 NC_012891.1 similar to cytochrome c-type biogenesis protein [Streptococcus pyogenes str. Manfredo]; cytochrome c-type biogenesis protein 1512400 ccdA 8110524 ccdA Streptococcus dysgalactiae subsp. equisimilis GGS_124 cytochrome c-type biogenesis protein YP_002997266.1 1511690 R 486410 CDS YP_002997267.1 251782964 8111608 complement(1512620..1513552) 1 NC_012891.1 similar to magnesium and cobalt transport protein [Streptococcus pyogenes MGAS10394]; magnesium and cobalt transport protein 1513552 corA 8111608 corA Streptococcus dysgalactiae subsp. equisimilis GGS_124 magnesium and cobalt transport protein YP_002997267.1 1512620 R 486410 CDS YP_002997268.1 251782965 8111641 complement(1513644..1514624) 1 NC_012891.1 similar to oxidoreductase [Streptococcus pyogenes str. Manfredo]; oxidoreductase 1514624 8111641 SDEG_1559 Streptococcus dysgalactiae subsp. equisimilis GGS_124 oxidoreductase YP_002997268.1 1513644 R 486410 CDS YP_002997269.1 251782966 8112146 1515191..1515382 1 NC_012891.1 similar to hypothetical protein M6 Spy1308 [Streptococcus pyogenes MGAS10394]; hypothetical protein 1515382 8112146 SDEG_1560 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002997269.1 1515191 D 486410 CDS YP_002997270.1 251782967 8112147 1515523..1516392 1 NC_012891.1 similar to hypothetical protein SpyM50565 [Streptococcus pyogenes str. Manfredo]; hypothetical protein 1516392 8112147 SDEG_1561 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002997270.1 1515523 D 486410 CDS YP_002997271.1 251782968 8112148 complement(1516608..1519256) 1 NC_012891.1 valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain; valyl-tRNA synthetase 1519256 valS 8112148 valS Streptococcus dysgalactiae subsp. equisimilis GGS_124 valyl-tRNA synthetase YP_002997271.1 1516608 R 486410 CDS YP_002997272.1 251782969 8111947 complement(1519258..1519842) 1 NC_012891.1 similar to hypothetical protein M6 Spy1311 [Streptococcus pyogenes MGAS10394]; hypothetical protein 1519842 8111947 SDEG_1563 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002997272.1 1519258 R 486410 CDS YP_002997273.1 251782970 8112149 complement(1519818..1520408) 1 NC_012891.1 similar to acetyltransferase GNAT family [Streptococcus agalactiae 2603V/R]; GNAT family acetyltransferase 1520408 8112149 SDEG_1564 Streptococcus dysgalactiae subsp. equisimilis GGS_124 GNAT family acetyltransferase YP_002997273.1 1519818 R 486410 CDS YP_002997274.1 251782971 8112150 complement(1520422..1520805) 1 NC_012891.1 similar to glyoxalase/bleomycin resistance protein/dioxygenase [Streptococcus suis 89/1591]; bleomycin resistance protein 1520805 8112150 SDEG_1565 Streptococcus dysgalactiae subsp. equisimilis GGS_124 bleomycin resistance protein YP_002997274.1 1520422 R 486410 CDS YP_002997275.1 251782972 8112151 complement(1521160..1521555) 1 NC_012891.1 similar to hypothetical protein SPy 1571 [Streptococcus pyogenes M1 GAS]; hypothetical protein 1521555 8112151 SDEG_1566 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002997275.1 1521160 R 486410 CDS YP_002997276.1 251782973 8112152 complement(1521576..1521830) 1 NC_012891.1 similar to hypothetical protein M6 Spy1314 [Streptococcus pyogenes MGAS10394]; hypothetical protein 1521830 8112152 SDEG_1567 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002997276.1 1521576 R 486410 CDS YP_002997277.1 251782974 8112153 1522058..1522492 1 NC_012891.1 similar to hypothetical protein CLOBAR 02811 [Clostridium bartlettii DSM 16795]; hypothetical protein 1522492 8112153 SDEG_1568 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002997277.1 1522058 D 486410 CDS YP_002997278.1 251782975 8112154 1522506..1523873 1 NC_012891.1 similar to MOP/MATE family multidrug-resistance efflux pump NorM [Fusobacterium nucleatum subsp. polymorphum ATCC 10953]; MOP/MATE family multidrug-resistance efflux pumpNorM 1523873 norM2 8112154 norM2 Streptococcus dysgalactiae subsp. equisimilis GGS_124 MOP/MATE family multidrug-resistance efflux pumpNorM YP_002997278.1 1522506 D 486410 CDS YP_002997279.1 251782976 8112155 1524545..1525297 1 NC_012891.1 catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate; 3-deoxy-7-phosphoheptulonate synthase 1525297 aroA.2 8112155 aroA.2 Streptococcus dysgalactiae subsp. equisimilis GGS_124 3-deoxy-7-phosphoheptulonate synthase YP_002997279.1 1524545 D 486410 CDS YP_002997280.1 251782977 8112338 1525347..1526426 1 NC_012891.1 catalyzes the formation of 3-dehydroquinate from 3-deoxy-arabino-heptulonate 7-phosphate; functions in aromatic amino acid biosynthesis; 3-dehydroquinate synthase 1526426 aroB 8112338 aroB Streptococcus dysgalactiae subsp. equisimilis GGS_124 3-dehydroquinate synthase YP_002997280.1 1525347 D 486410 CDS YP_002997281.1 251782978 8112339 complement(1526842..1528824) 1 NC_012891.1 similar to adhesion protein [Streptococcus uberis]; adhesion protein 1528824 8112339 SDEG_1573 Streptococcus dysgalactiae subsp. equisimilis GGS_124 adhesion protein YP_002997281.1 1526842 R 486410 CDS YP_002997282.1 251782979 8112156 1528970..1529143 1 NC_012891.1 similar to hypothetical protein LSL 1395 [Lactobacillus salivarius UCC118]; hypothetical protein 1529143 8112156 SDEG_1574 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002997282.1 1528970 D 486410 CDS YP_002997283.1 251782980 8112157 complement(1529190..1530098) 1 NC_012891.1 similar to predicted permease [Streptococcus suis 05ZYH33]; permease 1530098 8112157 SDEG_1575 Streptococcus dysgalactiae subsp. equisimilis GGS_124 permease YP_002997283.1 1529190 R 486410 CDS YP_002997284.1 251782981 8112158 complement(1530240..1531160) 1 NC_012891.1 similar to shikimate 5-dehydrogenase [Streptococcus pyogenes M1 GAS]; shikimate 5-dehydrogenase 1531160 aroE 8112158 aroE Streptococcus dysgalactiae subsp. equisimilis GGS_124 shikimate 5-dehydrogenase YP_002997284.1 1530240 R 486410 CDS YP_002997285.1 251782982 8112341 complement(1531259..1534759) 1 NC_012891.1 similar to beta-galactosidase [Streptococcus pyogenes MGAS2096]; beta-galactosidase 1534759 lacZ 8112341 lacZ Streptococcus dysgalactiae subsp. equisimilis GGS_124 beta-galactosidase YP_002997285.1 1531259 R 486410 CDS YP_002997286.1 251782983 8110888 complement(1534689..1536173) 1 NC_012891.1 similar to two-component response regulator [Streptococcus pyogenes MGAS6180]; two-component response regulator 1536173 yesN 8110888 yesN Streptococcus dysgalactiae subsp. equisimilis GGS_124 two-component response regulator YP_002997286.1 1534689 R 486410 CDS YP_002997287.1 251782984 8111965 complement(1536173..1537900) 1 NC_012891.1 similar to two-component sensor kinase [Streptococcus pyogenes MGAS6180]; two-component sensor kinase 1537900 yesM 8111965 yesM Streptococcus dysgalactiae subsp. equisimilis GGS_124 two-component sensor kinase YP_002997287.1 1536173 R 486410 CDS YP_002997288.1 251782985 8111962 complement(1537887..1538492) 1 NC_012891.1 similar to hypothetical membrane spanning protein [Streptococcus pyogenes MGAS10394]; hypothetical protein 1538492 8111962 SDEG_1580 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002997288.1 1537887 R 486410 CDS YP_002997289.1 251782986 8112159 complement(1538800..1540245) 1 NC_012891.1 similar to sugar-binding protein [Streptococcus pyogenes MGAS10750]; sugar-binding protein 1540245 8112159 SDEG_1581 Streptococcus dysgalactiae subsp. equisimilis GGS_124 sugar-binding protein YP_002997289.1 1538800 R 486410 CDS YP_002997290.1 251782987 8112160 complement(1540325..1541251) 1 NC_012891.1 similar to binding-protein-dependent transport system membrane protein [Streptococcus pyogenes str. Manfredo]; binding-protein-dependent transport system membrane protein 1541251 8112160 SDEG_1582 Streptococcus dysgalactiae subsp. equisimilis GGS_124 binding-protein-dependent transport system membrane protein YP_002997290.1 1540325 R 486410 CDS YP_002997291.1 251782988 8112161 complement(1541261..1542259) 1 NC_012891.1 similar to sugar transport system permease protein [Streptococcus pyogenes MGAS10270]; sugar transport system permease 1542259 8112161 SDEG_1583 Streptococcus dysgalactiae subsp. equisimilis GGS_124 sugar transport system permease YP_002997291.1 1541261 R 486410 CDS YP_002997292.1 251782989 8112162 1542362..1543285 1 NC_012891.1 similar to glucokinase [Streptococcus pyogenes MGAS10394]; glucokinase 1543285 8112162 SDEG_1584 Streptococcus dysgalactiae subsp. equisimilis GGS_124 glucokinase YP_002997292.1 1542362 D 486410 CDS YP_002997293.1 251782990 8112163 1543289..1545463 1 NC_012891.1 similar to alpha-1,2-mannosidase [Geobacillus sp. Y412MC10]; alpha-1,2-mannosidase 1545463 8112163 SDEG_1585 Streptococcus dysgalactiae subsp. equisimilis GGS_124 alpha-1,2-mannosidase YP_002997293.1 1543289 D 486410 CDS YP_002997294.1 251782991 8112164 complement(1545624..1546316) 1 NC_012891.1 similar to two-component response regulator histidine kinase [Streptococcus pyogenes MGAS315]; two-component response regulator histidine kinase 1546316 8112164 SDEG_1586 Streptococcus dysgalactiae subsp. equisimilis GGS_124 two-component response regulator histidine kinase YP_002997294.1 1545624 R 486410 CDS YP_002997295.1 251782992 8112165 complement(1546689..1548080) 1 NC_012891.1 similar tobeta-glucosidase [Streptococcus pyogenes MGAS5005]; beta-glucosidase 1548080 8112165 SDEG_1587 Streptococcus dysgalactiae subsp. equisimilis GGS_124 beta-glucosidase YP_002997295.1 1546689 R 486410 CDS YP_002997296.1 251782993 8112166 complement(1548105..1549799) 1 NC_012891.1 similar to hyaluronoglucosaminidase [Streptococcus pyogenes MGAS10394]; hyaluronoglucosaminidase 1549799 hyl 8112166 hyl Streptococcus dysgalactiae subsp. equisimilis GGS_124 hyaluronoglucosaminidase YP_002997296.1 1548105 R 486410 CDS YP_002997297.1 251782994 8112045 complement(1549850..1550890) 1 NC_012891.1 similar to transcriptional regulator GntR family [Streptococcus pyogenes MGAS5005]; GntR family transcriptional regulator 1550890 8112045 SDEG_1589 Streptococcus dysgalactiae subsp. equisimilis GGS_124 GntR family transcriptional regulator YP_002997297.1 1549850 R 486410 CDS YP_002997298.1 251782995 8112167 1551022..1552308 1 NC_012891.1 similar tohypothetical protein M28 Spy1357 [Streptococcus pyogenes MGAS6180]; hypothetical protein 1552308 8112167 SDEG_1590 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002997298.1 1551022 D 486410 CDS YP_002997299.1 251782996 8112168 1552323..1555028 1 NC_012891.1 similar toalpha-mannosidase [Streptococcus pyogenes MGAS5005]; alpha-mannosidase 1555028 8112168 SDEG_1591 Streptococcus dysgalactiae subsp. equisimilis GGS_124 alpha-mannosidase YP_002997299.1 1552323 D 486410 CDS YP_002997300.1 251782997 8112169 complement(1555133..1555546) 1 NC_012891.1 similar to histone acetyltransferase HPA2 [Streptococcus sanguinis SK36]; histone acetyltransferase HPA2 1555546 8112169 SDEG_1592 Streptococcus dysgalactiae subsp. equisimilis GGS_124 histone acetyltransferase HPA2 YP_002997300.1 1555133 R 486410 CDS YP_002997301.1 251782998 8112170 complement(1555527..1556147) 1 NC_012891.1 similar to phosphinothricin N-acetyltransferase [Streptococcus equi subsp. zooepidemicus MGCS10565]; phosphinothricin N-acetyltransferase 1556147 pat 8112170 pat Streptococcus dysgalactiae subsp. equisimilis GGS_124 phosphinothricin N-acetyltransferase YP_002997301.1 1555527 R 486410 CDS YP_002997302.1 251782999 8111753 complement(1556989..1557981) 1 NC_012891.1 similar to hypothetical protein spyM18 1170 [Streptococcus pyogenes MGAS8232]; hypothetical protein 1557981 8111753 SDEG_1594 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002997302.1 1556989 R 486410 CDS YP_002997303.1 251783000 8112171 complement(1558151..1559818) 1 NC_012891.1 similar to AMP-dependent synthetase and ligase [Rhodopseudomonas palustris BisA53]; AMP-dependent synthetase and ligase 1559818 8112171 SDEG_1595 Streptococcus dysgalactiae subsp. equisimilis GGS_124 AMP-dependent synthetase and ligase YP_002997303.1 1558151 R 486410 CDS YP_002997304.1 251783001 8112172 complement(1559875..1560789) 1 NC_012891.1 similar to hypothetical protein CLOHIR 01137 [Clostridium hiranonis DSM 13275]; hypothetical protein 1560789 8112172 SDEG_1596 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002997304.1 1559875 R 486410 CDS YP_002997305.1 251783002 8112173 complement(1560786..1561979) 1 NC_012891.1 similar to acyl-CoA acetyltransferase FadA [Carnobacterium sp. AT7]; acyl-CoA acetyltransferase 1561979 8112173 SDEG_1597 Streptococcus dysgalactiae subsp. equisimilis GGS_124 acyl-CoA acetyltransferase YP_002997305.1 1560786 R 486410 CDS YP_002997306.1 251783003 8112174 complement(1562017..1564242) 1 NC_012891.1 similar to fatty oxidation complex protein [Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305]; fatty oxidation complex protein 1564242 8112174 SDEG_1598 Streptococcus dysgalactiae subsp. equisimilis GGS_124 fatty oxidation complex protein YP_002997306.1 1562017 R 486410 CDS YP_002997307.1 251783004 8112175 1564320..1564442 1 NC_012891.1 similar to hypothetical protein SSU98 0605 [Streptococcus suis 98HAH33]; hypothetical protein 1564442 8112175 SDEG_1599 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002997307.1 1564320 D 486410 CDS YP_002997308.1 251783005 8112176 1564530..1564766 1 NC_012891.1 similar to transposase IS4 [Streptococcus suis 89/1591]; transposase IS4 1564766 8112176 SDEG_1600 Streptococcus dysgalactiae subsp. equisimilis GGS_124 transposase IS4 YP_002997308.1 1564530 D 486410 CDS YP_002997309.1 251783006 8112177 complement(1565172..1565918) 1 NC_012891.1 no hit; hypothetical protein 1565918 8112177 SDEG_1601 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002997309.1 1565172 R 486410 CDS YP_002997310.1 251783007 8112178 complement(1565920..1566849) 1 NC_012891.1 similar to ABC transporter ATP-binding protein [Listeria monocytogenes str. 4b F2365]; ABC transporter ATP-binding protein 1566849 8112178 SDEG_1602 Streptococcus dysgalactiae subsp. equisimilis GGS_124 ABC transporter ATP-binding protein YP_002997310.1 1565920 R 486410 CDS YP_002997311.1 251783008 8112179 complement(1567172..1567315) 1 NC_012891.1 similar to hypothetical protein PEPMIC 00589 [Peptostreptococcus micros ATCC 33270]; hypothetical protein 1567315 8112179 SDEG_1603 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002997311.1 1567172 R 486410 CDS YP_002997312.1 251783009 8112180 complement(1567309..1568667) 1 NC_012891.1 similar to RNA methyltransferase [Streptococcus pyogenes M1 GAS]; RNA methyltransferase 1568667 8112180 SDEG_1604 Streptococcus dysgalactiae subsp. equisimilis GGS_124 RNA methyltransferase YP_002997312.1 1567309 R 486410 CDS YP_002997313.1 251783010 8112181 complement(1568857..1569039) 1 NC_012891.1 similar to unknown phage protein [Streptococcus pyogenes MGAS10394]; phage protein 1569039 8112181 SDEG_1605 Streptococcus dysgalactiae subsp. equisimilis GGS_124 phage protein YP_002997313.1 1568857 R 486410 CDS YP_002997314.1 251783011 8112182 1569210..1569584 1 NC_012891.1 similar to protein gp30 [bacteriophage A118] [Listeria monocytogenes EGD-e]; protein gp30 1569584 8112182 SDEG_1606 Streptococcus dysgalactiae subsp. equisimilis GGS_124 protein gp30 YP_002997314.1 1569210 D 486410 CDS YP_002997315.1 251783012 8112183 1569584..1570186 1 NC_012891.1 similar to hypothetical protein PEPE 1706 [Pediococcus pentosaceus ATCC 25745]; hypothetical protein 1570186 8112183 SDEG_1607 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002997315.1 1569584 D 486410 CDS YP_002997316.1 251783013 8112184 1570158..1570403 1 NC_012891.1 similar to hypothetical protein phiPH15 gp59 [Streptococcus phage PH15]; hypothetical protein 1570403 8112184 SDEG_1608 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002997316.1 1570158 D 486410 CDS YP_002997317.1 251783014 8112185 complement(1570914..1572263) 1 NC_012891.1 similar to prophage LambdaSa2 lysin [Streptococcus agalactiae 2603V/R]; prophage LambdaSa2, lysin 1572263 8112185 SDEG_1609 Streptococcus dysgalactiae subsp. equisimilis GGS_124 prophage LambdaSa2, lysin YP_002997317.1 1570914 R 486410 CDS YP_002997318.1 251783015 8112186 complement(1572265..1572597) 1 NC_012891.1 similar to N-acetylmuramoyl-L-alanine amidase [Streptococcus pyogenes MGAS5005]; N-acetylmuramoyl-L-alanine amidase 1572597 8112186 SDEG_1610 Streptococcus dysgalactiae subsp. equisimilis GGS_124 N-acetylmuramoyl-L-alanine amidase YP_002997318.1 1572265 R 486410 CDS YP_002997319.1 251783016 8112187 complement(1572597..1572920) 1 NC_012891.1 similar to phage protein [bacteriophage 10750.2]; phage protein 1572920 8112187 SDEG_1611 Streptococcus dysgalactiae subsp. equisimilis GGS_124 phage protein YP_002997319.1 1572597 R 486410 CDS YP_002997320.1 251783017 8112188 complement(1572933..1573097) 1 NC_012891.1 similar to phage protein [Streptococcus pyogenes MGAS5005]; phage protein 1573097 8112188 SDEG_1612 Streptococcus dysgalactiae subsp. equisimilis GGS_124 phage protein YP_002997320.1 1572933 R 486410 CDS YP_002997321.1 251783018 8112189 complement(1573069..1573419) 1 NC_012891.1 similar to hypothetical protein SpyM3 1309 [Streptococcus pyogenes MGAS315]; hypothetical protein 1573419 8112189 SDEG_1613 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002997321.1 1573069 R 486410 CDS YP_002997322.1 251783019 8112190 complement(1573435..1575312) 1 NC_012891.1 similar to prophage LambdaSa1 minor structural protein [Streptococcus agalactiae 18RS21]; prophage LambdaSa1, minor structural protein 1575312 8112190 SDEG_1614 Streptococcus dysgalactiae subsp. equisimilis GGS_124 prophage LambdaSa1, minor structural protein YP_002997322.1 1573435 R 486410 CDS YP_002997323.1 251783020 8112191 complement(1575323..1578691) 1 NC_012891.1 similar to phage protein [Streptococcus pyogenes MGAS5005]; phage protein 1578691 8112191 SDEG_1615 Streptococcus dysgalactiae subsp. equisimilis GGS_124 phage protein YP_002997323.1 1575323 R 486410 CDS YP_002997324.1 251783021 8112192 complement(1578692..1580176) 1 NC_012891.1 similar to phage tail protein [bacteriophage 10750.2]; phage tail protein 1580176 8112192 SDEG_1616 Streptococcus dysgalactiae subsp. equisimilis GGS_124 phage tail protein YP_002997324.1 1578692 R 486410 CDS YP_002997325.1 251783022 8112193 complement(1580177..1581361) 1 NC_012891.1 similar to platlet-binding protein minor tail fiber protein - phage associated [Streptococcus pyogenes MGAS315]; platlet-binding protein, minor tailfiber protein 1581361 8112193 SDEG_1617 Streptococcus dysgalactiae subsp. equisimilis GGS_124 platlet-binding protein, minor tailfiber protein YP_002997325.1 1580177 R 486410 CDS YP_002997326.1 251783023 8112194 complement(1581580..1582140) 1 NC_012891.1 similar to endodeoxyribonuclease [Lactococcus phage r1t]; endodeoxyribonuclease 1582140 8112194 SDEG_1618 Streptococcus dysgalactiae subsp. equisimilis GGS_124 endodeoxyribonuclease YP_002997326.1 1581580 R 486410 CDS YP_002997327.1 251783024 8112195 complement(1582206..1582910) 1 NC_012891.1 similar to phage protein [bacteriophage 10750.2]; phage protein 1582910 8112195 SDEG_1619 Streptococcus dysgalactiae subsp. equisimilis GGS_124 phage protein YP_002997327.1 1582206 R 486410 CDS YP_002997328.1 251783025 8112196 complement(1582903..1583361) 1 NC_012891.1 similar to phage protein [Streptococcus pyogenes MGAS5005]; phage protein 1583361 8112196 SDEG_1620 Streptococcus dysgalactiae subsp. equisimilis GGS_124 phage protein YP_002997328.1 1582903 R 486410 CDS YP_002997329.1 251783026 8112197 complement(1583334..1583651) 1 NC_012891.1 similar to phage protein [Streptococcus pyogenes MGAS5005]; phage protein 1583651 8112197 SDEG_1621 Streptococcus dysgalactiae subsp. equisimilis GGS_124 phage protein YP_002997329.1 1583334 R 486410 CDS YP_002997330.1 251783027 8112198 complement(1583663..1584169) 1 NC_012891.1 similar to antigen A [Streptococcus pyogenes MGAS5005]; antigen A 1584169 8112198 SDEG_1622 Streptococcus dysgalactiae subsp. equisimilis GGS_124 antigen A YP_002997330.1 1583663 R 486410 CDS YP_002997331.1 251783028 8112199 complement(1584181..1584591) 1 NC_012891.1 similar to antigen B [Streptococcus pyogenes MGAS5005]; antigen B 1584591 8112199 SDEG_1623 Streptococcus dysgalactiae subsp. equisimilis GGS_124 antigen B YP_002997331.1 1584181 R 486410 CDS YP_002997332.1 251783029 8112200 complement(1584593..1584988) 1 NC_012891.1 similar to antigen C [bacteriophage 10750.2]; antigen C 1584988 8112200 SDEG_1624 Streptococcus dysgalactiae subsp. equisimilis GGS_124 antigen C YP_002997332.1 1584593 R 486410 CDS YP_002997333.1 251783030 8112201 complement(1584985..1585296) 1 NC_012891.1 similar to phage protein [bacteriophage 10750.2]; phage protein 1585296 8112201 SDEG_1625 Streptococcus dysgalactiae subsp. equisimilis GGS_124 phage protein YP_002997333.1 1584985 R 486410 CDS YP_002997334.1 251783031 8112202 complement(1585293..1585637) 1 NC_012891.1 similar to hypothetical protein SpyM3 1320 [Streptococcus pyogenes MGAS315]; hypothetical protein 1585637 8112202 SDEG_1626 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002997334.1 1585293 R 486410 CDS YP_002997335.1 251783032 8112203 complement(1585651..1585944) 1 NC_012891.1 similar to phage protein [bacteriophage 10750.2]; phage protein 1585944 8112203 SDEG_1627 Streptococcus dysgalactiae subsp. equisimilis GGS_124 phage protein YP_002997335.1 1585651 R 486410 CDS YP_002997336.1 251783033 8112204 complement(1585956..1586846) 1 NC_012891.1 similar to hypothetical protein SpyM3_1322 [Streptococcus pyogenes MGAS315]; hypothetical protein 1586846 8112204 SDEG_1628 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002997336.1 1585956 R 486410 CDS YP_002997337.1 251783034 8112205 complement(1586864..1587475) 1 NC_012891.1 similar to phage scaffold protein [bacteriophage 10750.2]; phage scaffold protein 1587475 8112205 SDEG_1629 Streptococcus dysgalactiae subsp. equisimilis GGS_124 phage scaffold protein YP_002997337.1 1586864 R 486410 CDS YP_002997338.1 251783035 8112206 complement(1587676..1587903) 1 NC_012891.1 similar to phage protein [bacteriophage 10750.2]; phage protein 1587903 8112206 SDEG_1630 Streptococcus dysgalactiae subsp. equisimilis GGS_124 phage protein YP_002997338.1 1587676 R 486410 CDS YP_002997339.1 251783036 8112207 complement(1587910..1588818) 1 NC_012891.1 similar to phage protein [bacteriophage 10750.2]; phage protein 1588818 8112207 SDEG_1631 Streptococcus dysgalactiae subsp. equisimilis GGS_124 phage protein YP_002997339.1 1587910 R 486410 CDS YP_002997340.1 251783037 8112208 complement(1588787..1590112) 1 NC_012891.1 similar to portal protein [bacteriophage 10750.2]; portal protein 1590112 8112208 SDEG_1632 Streptococcus dysgalactiae subsp. equisimilis GGS_124 portal protein YP_002997340.1 1588787 R 486410 CDS YP_002997341.1 251783038 8112209 complement(1590112..1591386) 1 NC_012891.1 similar to Terminase large subunit [bacteriophage 10750.2]; terminase large subunit 1591386 8112209 SDEG_1633 Streptococcus dysgalactiae subsp. equisimilis GGS_124 terminase large subunit YP_002997341.1 1590112 R 486410 CDS YP_002997342.1 251783039 8112210 complement(1591376..1591756) 1 NC_012891.1 similar to phage protein [bacteriophage 10750.2]; phage protein 1591756 8112210 SDEG_1634 Streptococcus dysgalactiae subsp. equisimilis GGS_124 phage protein YP_002997342.1 1591376 R 486410 CDS YP_002997343.1 251783040 8112211 1591842..1591994 1 NC_012891.1 similar to phage protein [Streptococcus pyogenes MGAS10750]; phage protein 1591994 8112211 SDEG_1635 Streptococcus dysgalactiae subsp. equisimilis GGS_124 phage protein YP_002997343.1 1591842 D 486410 CDS YP_002997344.1 251783041 8112212 complement(1592285..1592725) 1 NC_012891.1 similar to phage encoded transcriptional regulator ArpU family [bacteriophage 10750.2]; ArpU family phage encoded transcriptional regulator 1592725 8112212 SDEG_1636 Streptococcus dysgalactiae subsp. equisimilis GGS_124 ArpU family phage encoded transcriptional regulator YP_002997344.1 1592285 R 486410 CDS YP_002997345.1 251783042 8112213 complement(1592765..1592860) 1 NC_012891.1 similar to hypothetical protein MGAS9429 Spy0819 [bacteriophage 9429.2]; hypothetical protein 1592860 8112213 SDEG_1637 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002997345.1 1592765 R 486410 CDS YP_002997346.1 251783043 8112214 complement(1593083..1593616) 1 NC_012891.1 similar to hypothetical protein SpyM50655 [Streptococcus pyogenes str. Manfredo]; hypothetical protein 1593616 8112214 SDEG_1638 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002997346.1 1593083 R 486410 CDS YP_002997347.1 251783044 8112215 complement(1593606..1593854) 1 NC_012891.1 no hit; hypothetical protein 1593854 8112215 SDEG_1639 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002997347.1 1593606 R 486410 CDS YP_002997348.1 251783045 8112216 complement(1593858..1594127) 1 NC_012891.1 similar to phage protein [Streptococcus pyogenes MGAS5005]; phage protein 1594127 8112216 SDEG_1640 Streptococcus dysgalactiae subsp. equisimilis GGS_124 phage protein YP_002997348.1 1593858 R 486410 CDS YP_002997349.1 251783046 8112379 complement(1594124..1594528) 1 NC_012891.1 similar to hypothetical protein SpyoM01000037 [Streptococcus pyogenes M49 591]; hypothetical protein 1594528 8112379 SDEG_1641 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002997349.1 1594124 R 486410 CDS YP_002997350.1 251783047 8112380 complement(1594525..1594737) 1 NC_012891.1 similar to Orf80 [bacteriophage phi31.1]; phage protein orf80 1594737 orf80 8112380 orf80 Streptococcus dysgalactiae subsp. equisimilis GGS_124 phage protein orf80 YP_002997350.1 1594525 R 486410 CDS YP_002997351.1 251783048 8111745 complement(1594787..1595122) 1 NC_012891.1 no hit; hypothetical protein 1595122 8111745 SDEG_1643 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002997351.1 1594787 R 486410 CDS YP_002997352.1 251783049 8112381 complement(1595115..1595402) 1 NC_012891.1 similar to hypothetical protein spyM18 1285 [Streptococcus pyogenes MGAS8232]; hypothetical protein 1595402 8112381 SDEG_1644 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002997352.1 1595115 R 486410 CDS YP_002997353.1 251783050 8112382 complement(1595399..1595647) 1 NC_012891.1 similar to hypothetical protein SpyM3 1246 [Streptococcus pyogenes MGAS315]; hypothetical protein 1595647 8112382 SDEG_1645 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002997353.1 1595399 R 486410 CDS YP_002997354.1 251783051 8112383 complement(1595644..1596000) 1 NC_012891.1 similar to phage protein [bacteriophage 10750.1]; phage protein 1596000 8112383 SDEG_1646 Streptococcus dysgalactiae subsp. equisimilis GGS_124 phage protein YP_002997354.1 1595644 R 486410 CDS YP_002997355.1 251783052 8112384 complement(1595997..1596437) 1 NC_012891.1 similar to phage protein [Streptococcus pyogenes MGAS6180]; phage protein 1596437 8112384 SDEG_1647 Streptococcus dysgalactiae subsp. equisimilis GGS_124 phage protein YP_002997355.1 1595997 R 486410 CDS YP_002997356.1 251783053 8112385 complement(1596437..1596640) 1 NC_012891.1 similar to phage protein [Streptococcus pyogenes MGAS6180]; phage protein 1596640 8112385 SDEG_1648 Streptococcus dysgalactiae subsp. equisimilis GGS_124 phage protein YP_002997356.1 1596437 R 486410 CDS YP_002997357.1 251783054 8112386 complement(1596646..1597065) 1 NC_012891.1 similar to single strand binding protein [Streptococcus pyogenes MGAS8232]; single strand binding protein 1597065 ssb 8112386 ssb Streptococcus dysgalactiae subsp. equisimilis GGS_124 single strand binding protein YP_002997357.1 1596646 R 486410 CDS YP_002997358.1 251783055 8110503 complement(1597058..1597732) 1 NC_012891.1 similar to phage single-strand DNA binding protein [Streptococcus pyogenes MGAS5005]; phage single-strand DNA-binding protein 1597732 ssb1 8110503 ssb1 Streptococcus dysgalactiae subsp. equisimilis GGS_124 phage single-strand DNA-binding protein YP_002997358.1 1597058 R 486410 CDS YP_002997359.1 251783056 8110504 complement(1597733..1598215) 1 NC_012891.1 similar to phage protein [Streptococcus pyogenes MGAS5005]; phage protein 1598215 8110504 SDEG_1651 Streptococcus dysgalactiae subsp. equisimilis GGS_124 phage protein YP_002997359.1 1597733 R 486410 CDS YP_002997360.1 251783057 8112387 complement(1598236..1598490) 1 NC_012891.1 similar to hypothetical protein SpyM3 1252 [Streptococcus pyogenes MGAS315]; hypothetical protein 1598490 8112387 SDEG_1652 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002997360.1 1598236 R 486410 CDS YP_002997361.1 251783058 8112388 complement(1598477..1598827) 1 NC_012891.1 similar to hypothetical protein spyM18 1799 [Streptococcus pyogenes MGAS8232]; hypothetical protein 1598827 8112388 SDEG_1653 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002997361.1 1598477 R 486410 CDS YP_002997362.1 251783059 8112389 complement(1598837..1598974) 1 NC_012891.1 similar to phage protein [Streptococcus pyogenes MGAS5005]; phage protein 1598974 8112389 SDEG_1654 Streptococcus dysgalactiae subsp. equisimilis GGS_124 phage protein YP_002997362.1 1598837 R 486410 CDS YP_002997363.1 251783060 8112390 complement(1598965..1599747) 1 NC_012891.1 similar to phage DNA replication protein [Streptococcus pyogenes str. Manfredo]; phage DNA replication protein 1599747 8112390 SDEG_1655 Streptococcus dysgalactiae subsp. equisimilis GGS_124 phage DNA replication protein YP_002997363.1 1598965 R 486410 CDS YP_002997364.1 251783061 8112391 complement(1599734..1600549) 1 NC_012891.1 similar to COG3935, primosome component and related proteins [Streptococcus pyogenes M49 591]; primosome component and related proteins 1600549 8112391 SDEG_1656 Streptococcus dysgalactiae subsp. equisimilis GGS_124 primosome component and related proteins YP_002997364.1 1599734 R 486410 CDS YP_002997365.1 251783062 8112392 complement(1600550..1600756) 1 NC_012891.1 similar to phage protein [bacteriophage 10750.1]; phage protein 1600756 8112392 SDEG_1657 Streptococcus dysgalactiae subsp. equisimilis GGS_124 phage protein YP_002997365.1 1600550 R 486410 CDS YP_002997366.1 251783063 8112393 complement(1600737..1600877) 1 NC_012891.1 similar to phage protein [Streptococcus pyogenes MGAS6180]; phage protein 1600877 8112393 SDEG_1658 Streptococcus dysgalactiae subsp. equisimilis GGS_124 phage protein YP_002997366.1 1600737 R 486410 CDS YP_002997367.1 251783064 8112394 complement(1600908..1601159) 1 NC_012891.1 similar to phage protein [bacteriophage 10750.2]; phage protein 1601159 8112394 SDEG_1659 Streptococcus dysgalactiae subsp. equisimilis GGS_124 phage protein YP_002997367.1 1600908 R 486410 CDS YP_002997368.1 251783065 8112395 complement(1601289..1601501) 1 NC_012891.1 similar to hypothetical protein SpyM50475 [Streptococcus pyogenes str. Manfredo]; hypothetical protein 1601501 8112395 SDEG_1660 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002997368.1 1601289 R 486410 CDS YP_002997369.1 251783066 8112396 1601698..1602039 1 NC_012891.1 similar to hypothetical protein SpyM50474 [Streptococcus pyogenes str. Manfredo]; hypothetical protein 1602039 8112396 SDEG_1661 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002997369.1 1601698 D 486410 CDS YP_002997370.1 251783067 8112397 1602023..1602400 1 NC_012891.1 similar to cI-like repressor metallo-prtoeinase motif - phage associated [Streptococcus pyogenes MGAS315]; cI-like repressor 1602400 8112397 SDEG_1662 Streptococcus dysgalactiae subsp. equisimilis GGS_124 cI-like repressor YP_002997370.1 1602023 D 486410 CDS YP_002997371.1 251783068 8112398 1602409..1603095 1 NC_012891.1 similar to phage protein [Streptococcus pyogenes MGAS10750]; phage protein 1603095 8112398 SDEG_1663 Streptococcus dysgalactiae subsp. equisimilis GGS_124 phage protein YP_002997371.1 1602409 D 486410 CDS YP_002997372.1 251783069 8112399 1603132..1603281 1 NC_012891.1 similar to hypothetical protein SPs0508 [Streptococcus pyogenes SSI-1]; hypothetical protein 1603281 8112399 SDEG_1664 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002997372.1 1603132 D 486410 CDS YP_002997373.1 251783070 8112400 1603208..1604434 1 NC_012891.1 similar to phage integrase [Streptococcus pyogenes MGAS8232]; phage integrase 1604434 int 8112400 int Streptococcus dysgalactiae subsp. equisimilis GGS_124 phage integrase YP_002997373.1 1603208 D 486410 CDS YP_002997374.1 251783071 8110870 1604582..1605358 1 NC_012891.1 binds RecA and inhibits RecA-mediated DNA strand exchange and ATP hydrolysis and coprotease activities; recombination regulator RecX 1605358 recX 8110870 recX Streptococcus dysgalactiae subsp. equisimilis GGS_124 recombination regulator RecX YP_002997374.1 1604582 D 486410 CDS YP_002997375.1 251783072 8111040 1605440..1605973 1 NC_012891.1 similar to hypothetical cytosolic protein [Streptococcus pyogenes MGAS10394]; hypothetical protein 1605973 8111040 SDEG_1667 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002997375.1 1605440 D 486410 CDS YP_002997376.1 251783073 8112401 1606027..1606338 1 NC_012891.1 similar to hypothetical protein Sez 1543 [Streptococcus equi subsp. zooepidemicus MGCS10565]; hypothetical protein 1606338 8112401 SDEG_1668 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002997376.1 1606027 D 486410 CDS YP_002997377.1 251783074 8112413 complement(1612537..1613655) 1 NC_012891.1 similar to transposase [Streptococcus pyogenes MGAS10270]; transposase 1613655 8112413 SDEG_1680 Streptococcus dysgalactiae subsp. equisimilis GGS_124 transposase YP_002997377.1 1612537 R 486410 CDS YP_002997378.1 251783075 8112414 complement(1613779..1614327) 1 NC_012891.1 similar to ribosome-associated factor Y [Streptococcus pyogenes MGAS10394]; ribosome-associated factor Y 1614327 8112414 SDEG_1681 Streptococcus dysgalactiae subsp. equisimilis GGS_124 ribosome-associated factor Y YP_002997378.1 1613779 R 486410 CDS YP_002997379.1 251783076 8112415 complement(1614407..1615072) 1 NC_012891.1 similar to late competence protein [Streptococcus pyogenes str. Manfredo]; late competence protein 1615072 comFC 8112415 comFC Streptococcus dysgalactiae subsp. equisimilis GGS_124 late competence protein YP_002997379.1 1614407 R 486410 CDS YP_002997380.1 251783077 8111636 complement(1615044..1616369) 1 NC_012891.1 similar to late competence protein required for DNA uptake [Streptococcus pyogenes M1 GAS]; late competence protein required for DNA uptake 1616369 comFA 8111636 comFA Streptococcus dysgalactiae subsp. equisimilis GGS_124 late competence protein required for DNA uptake YP_002997380.1 1615044 R 486410 CDS YP_002997381.1 251783078 8111635 1616425..1617063 1 NC_012891.1 similar to hypothetical protein Sez 1548 [Streptococcus equi subsp. zooepidemicus MGCS10565]; Xaa-Pro dipeptidase 1617063 8111635 SDEG_1684 Streptococcus dysgalactiae subsp. equisimilis GGS_124 Xaa-Pro dipeptidase YP_002997381.1 1616425 D 486410 CDS YP_002997382.1 251783079 8112416 1617167..1618102 1 NC_012891.1 similar to cysteine synthase [Streptococcus pyogenes MGAS10750]; cysteine synthase 1618102 cysM 8112416 cysM Streptococcus dysgalactiae subsp. equisimilis GGS_124 cysteine synthase YP_002997382.1 1617167 D 486410 CDS YP_002997383.1 251783080 8111657 complement(1618255..1618614) 1 NC_012891.1 similar to S1-type RNA-binding domain [Streptococcus pyogenes MGAS10750]; hypothetical protein 1618614 8111657 SDEG_1686 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002997383.1 1618255 R 486410 CDS YP_002997384.1 251783081 8112417 complement(1618614..1620026) 1 NC_012891.1 similar to cyclophilin-type protein [Streptococcus pyogenes SSI-1]; cyclophilin-type protein 1620026 8112417 SDEG_1687 Streptococcus dysgalactiae subsp. equisimilis GGS_124 cyclophilin-type protein YP_002997384.1 1618614 R 486410 CDS YP_002997385.1 251783082 8112418 complement(1620051..1620698) 1 NC_012891.1 similar to two-component response regulator [Streptococcus pyogenes SSI-1]; two-component response regulator 1620698 yvqC 8112418 yvqC Streptococcus dysgalactiae subsp. equisimilis GGS_124 two-component response regulator YP_002997385.1 1620051 R 486410 CDS YP_002997386.1 251783083 8111969 complement(1620685..1621689) 1 NC_012891.1 similar to two-component sensor protein yvqE [Streptococcus pyogenes MGAS10394]; two-component sensor protein yvqE 1621689 yvqE 8111969 yvqE Streptococcus dysgalactiae subsp. equisimilis GGS_124 two-component sensor protein yvqE YP_002997386.1 1620685 R 486410 CDS YP_002997387.1 251783084 8111970 complement(1621686..1622378) 1 NC_012891.1 similar to transporter yvqF [Streptococcus pyogenes MGAS10394]; transporter yvqF 1622378 yvqF 8111970 yvqF Streptococcus dysgalactiae subsp. equisimilis GGS_124 transporter yvqF YP_002997387.1 1621686 R 486410 CDS YP_002997388.1 251783085 8111971 complement(1622505..1624400) 1 NC_012891.1 similar to serine/threonine-protein kinase [Streptococcus pyogenes str. Manfredo]; serine/threonine-protein kinase 1624400 stk1 8111971 stk1 Streptococcus dysgalactiae subsp. equisimilis GGS_124 serine/threonine-protein kinase YP_002997388.1 1622505 R 486410 CDS YP_002997389.1 251783086 8110507 complement(1624397..1625137) 1 NC_012891.1 similar to protein phosphatase 2C [Streptococcus pyogenes MGAS10394]; protein phosphatase 2C 1625137 pppL 8110507 pppL Streptococcus dysgalactiae subsp. equisimilis GGS_124 protein phosphatase 2C YP_002997389.1 1624397 R 486410 CDS YP_002997390.1 251783087 8111304 complement(1625175..1626533) 1 NC_012891.1 similar to 16S rRNA m(5)C 967 methyltransferase [Streptococcus pyogenes MGAS6180]; 16S rRNA m(5)C 967 methyltransferase 1626533 sunL 8111304 sunL Streptococcus dysgalactiae subsp. equisimilis GGS_124 16S rRNA m(5)C 967 methyltransferase YP_002997390.1 1625175 R 486410 CDS YP_002997391.1 251783088 8110511 complement(1626487..1627422) 1 NC_012891.1 modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet) which is important in translation initiation; inactivation of this gene in Escherichia coli severely impairs growth; methionyl-tRNA formyltransferase 1627422 fmt 8110511 fmt Streptococcus dysgalactiae subsp. equisimilis GGS_124 methionyl-tRNA formyltransferase YP_002997391.1 1626487 R 486410 CDS YP_002997392.1 251783089 8111900 complement(1627487..1629871) 1 NC_012891.1 binding of PriA to forked DNA starts the assembly of the primosome, also possesses 3'-5' helicase activity; primosome assembly protein PriA 1629871 priA 8111900 priA Streptococcus dysgalactiae subsp. equisimilis GGS_124 primosome assembly protein PriA YP_002997392.1 1627487 R 486410 CDS YP_002997393.1 251783090 8111309 complement(1629935..1630252) 1 NC_012891.1 Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits; DNA-directed RNA polymerase subunit omega 1630252 8111309 SDEG_1696 Streptococcus dysgalactiae subsp. equisimilis GGS_124 DNA-directed RNA polymerase subunit omega YP_002997393.1 1629935 R 486410 CDS YP_002997394.1 251783091 8112419 complement(1630268..1630900) 1 NC_012891.1 Essential for recycling GMP and indirectly, cGMP; guanylate kinase 1630900 gmk 8112419 gmk Streptococcus dysgalactiae subsp. equisimilis GGS_124 guanylate kinase YP_002997394.1 1630268 R 486410 CDS YP_002997395.1 251783092 8112015 complement(1631010..1632617) 1 NC_012891.1 similar to phosphohydrolase [Streptococcus pyogenes str. Manfredo]; hypothetical protein 1632617 8112015 SDEG_1698 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002997395.1 1631010 R 486410 CDS YP_002997396.1 251783093 8112420 complement(1632747..1633736) 1 NC_012891.1 similar to transcriptional regulators LysR family [Streptococcus pyogenes MGAS10394]; LysR family transcriptional regulator 1633736 8112420 SDEG_1699 Streptococcus dysgalactiae subsp. equisimilis GGS_124 LysR family transcriptional regulator YP_002997396.1 1632747 R 486410 CDS YP_002997397.1 251783094 8112421 1633842..1635029 1 NC_012891.1 similar to acetyl-CoA acetyltransferase [Streptococcus pyogenes MGAS2096]; acetyl-CoA acetyltransferase 1635029 atoB 8112421 atoB Streptococcus dysgalactiae subsp. equisimilis GGS_124 acetyl-CoA acetyltransferase YP_002997397.1 1633842 D 486410 CDS YP_002997398.1 251783095 8112355 1635113..1635703 1 NC_012891.1 similar to acetate CoA-transferase alpha subunit [Streptococcus pyogenes MGAS5005]; acetate CoA-transferase subunit alpha 1635703 atoD.1 8112355 atoD.1 Streptococcus dysgalactiae subsp. equisimilis GGS_124 acetate CoA-transferase subunit alpha YP_002997398.1 1635113 D 486410 CDS YP_002997399.1 251783096 8112356 1635813..1636364 1 NC_012891.1 similar to acetate CoA-transferase beta subunit [Streptococcus pyogenes MGAS5005]; acetate CoA-transferase subunit beta 1636364 atoA 8112356 atoA Streptococcus dysgalactiae subsp. equisimilis GGS_124 acetate CoA-transferase subunit beta YP_002997399.1 1635813 D 486410 CDS YP_002997400.1 251783097 8112354 1636397..1636864 1 NC_012891.1 similar to short chain dehydrogenase [Streptococcus pyogenes MGAS6180]; short chain dehydrogenase 1636864 8112354 SDEG_1703 Streptococcus dysgalactiae subsp. equisimilis GGS_124 short chain dehydrogenase YP_002997400.1 1636397 D 486410 CDS YP_002997401.1 251783098 8112422 1636867..1637817 1 NC_012891.1 similar to D-beta-hydroxybutyrate permease [Streptococcus pyogenes MGAS10750]; D-beta-hydroxybutyrate permease 1637817 8112422 SDEG_1704 Streptococcus dysgalactiae subsp. equisimilis GGS_124 D-beta-hydroxybutyrate permease YP_002997401.1 1636867 D 486410 CDS YP_002997402.1 251783099 8112423 1638184..1638666 1 NC_012891.1 catalyzes the hydrolysis of S-ribosylhomocysteine to homocysteine and autoinducer-2; S-ribosylhomocysteinase 1638666 luxS 8112423 luxS Streptococcus dysgalactiae subsp. equisimilis GGS_124 S-ribosylhomocysteinase YP_002997402.1 1638184 D 486410 CDS YP_002997403.1 251783100 8110912 complement(1638780..1640261) 1 NC_012891.1 similar to hypothetical protein spyM18 1655 [Streptococcus pyogenes MGAS8232]; hypothetical protein 1640261 8110912 SDEG_1706 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002997403.1 1638780 R 486410 CDS YP_002997404.1 251783101 8112424 complement(1640275..1641429) 1 NC_012891.1 similar to methyltransferase [Streptococcus pyogenes MGAS10270]; methyltransferase 1641429 8112424 SDEG_1707 Streptococcus dysgalactiae subsp. equisimilis GGS_124 methyltransferase YP_002997404.1 1640275 R 486410 CDS YP_002997405.1 251783102 8112425 complement(1641874..1642200) 1 NC_012891.1 similar to cell division initiation protein [Streptococcus pyogenes MGAS5005]; cell division initiation protein 1642200 8112425 SDEG_1708 Streptococcus dysgalactiae subsp. equisimilis GGS_124 cell division initiation protein YP_002997405.1 1641874 R 486410 CDS YP_002997406.1 251783103 8112426 complement(1642322..1642837) 1 NC_012891.1 similar to hypothetical protein spyM18 1659 [Streptococcus pyogenes MGAS8232]; hypothetical protein 1642837 8112426 SDEG_1709 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002997406.1 1642322 R 486410 CDS YP_002997407.1 251783104 8112427 1642918..1643526 1 NC_012891.1 functions in homologous recombination, DNA repair, and chromosome segregation; binds preferentially to three- and four-stranded DNA intermediates; introduces specific nick sites in four-stranded DNA substrates; functions similarly to Escherichia coli RuvC; Holliday junction-specific endonuclease 1643526 recU 8112427 recU Streptococcus dysgalactiae subsp. equisimilis GGS_124 Holliday junction-specific endonuclease YP_002997407.1 1642918 D 486410 CDS YP_002997408.1 251783105 8111039 1643513..1645687 1 NC_012891.1 similar to multimodular transpeptidase-transglycosylase PBP 1A [Streptococcus pyogenes MGAS10750]; multimodular transpeptidase-transglycosylase 1645687 pbp1A 8111039 pbp1A Streptococcus dysgalactiae subsp. equisimilis GGS_124 multimodular transpeptidase-transglycosylase YP_002997408.1 1643513 D 486410 CDS YP_002997409.1 251783106 8111754 complement(1645733..1647064) 1 NC_012891.1 similar to aminopeptidase C [Streptococcus pyogenes MGAS315]; aminopeptidase C 1647064 pepC 8111754 pepC Streptococcus dysgalactiae subsp. equisimilis GGS_124 aminopeptidase C YP_002997409.1 1645733 R 486410 CDS YP_002997410.1 251783107 8111274 complement(1647245..1648111) 1 NC_012891.1 catalyzes the formation of nicotinamide adenine dinucleotide (NAD) from nicotinic acid adenine dinucleotide (NAAD) using either ammonia or glutamine as the amide donor and ATP; ammonia-utilizing enzymes include the ones from Bacillus and Escherichia coli while glutamine-utilizing enzymes include the Mycobacterial one; forms homodimers; NAD synthetase 1648111 nadE 8111274 nadE Streptococcus dysgalactiae subsp. equisimilis GGS_124 NAD synthetase YP_002997410.1 1647245 R 486410 CDS YP_002997411.1 251783108 8111705 complement(1648071..1649525) 1 NC_012891.1 catalyzes the formation of 5-phospho-alpha-D-ribose 1-diphosphate and nicotinate from nicotinate D-ribonucleotide and diphosphate; nicotinate phosphoribosyltransferase 1649525 8111705 SDEG_1714 Streptococcus dysgalactiae subsp. equisimilis GGS_124 nicotinate phosphoribosyltransferase YP_002997411.1 1648071 R 486410 CDS YP_002997412.1 251783109 8112428 complement(1649695..1651086) 1 NC_012891.1 similar to amino acid permease [Streptococcus pyogenes MGAS6180]; amino acid permease 1651086 8112428 SDEG_1715 Streptococcus dysgalactiae subsp. equisimilis GGS_124 amino acid permease YP_002997412.1 1649695 R 486410 CDS YP_002997413.1 251783110 8112429 complement(1651236..1652153) 1 NC_012891.1 similar to thioredoxin reductase [Streptococcus pyogenes MGAS10394]; thioredoxin reductase 1652153 8112429 SDEG_1716 Streptococcus dysgalactiae subsp. equisimilis GGS_124 thioredoxin reductase YP_002997413.1 1651236 R 486410 CDS YP_002997414.1 251783111 8112430 complement(1652216..1652440) 1 NC_012891.1 similar to hypothetical protein SpyM50430 [Streptococcus pyogenes str. Manfredo]; hypothetical protein 1652440 8112430 SDEG_1717 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002997414.1 1652216 R 486410 CDS YP_002997415.1 251783112 8112431 complement(1652544..1653290) 1 NC_012891.1 similar to transporter [Streptococcus pyogenes MGAS6180]; transporter 1653290 8112431 SDEG_1718 Streptococcus dysgalactiae subsp. equisimilis GGS_124 transporter YP_002997415.1 1652544 R 486410 CDS YP_002997416.1 251783113 8112432 complement(1653287..1654090) 1 NC_012891.1 similar to amino acid ABC transporter permease protein [Streptococcus pyogenes MGAS10394]; amino acid ABC transporter permease 1654090 8112432 SDEG_1719 Streptococcus dysgalactiae subsp. equisimilis GGS_124 amino acid ABC transporter permease YP_002997416.1 1653287 R 486410 CDS YP_002997417.1 251783114 8112433 complement(1654234..1655067) 1 NC_012891.1 similar to amino-acid ABC transporter extracellular-binding protein precursor [Streptococcus equi subsp. zooepidemicus MGCS10565]; amino acid ABC transporter extracellular-binding protein 1655067 8112433 SDEG_1720 Streptococcus dysgalactiae subsp. equisimilis GGS_124 amino acid ABC transporter extracellular-binding protein YP_002997417.1 1654234 R 486410 CDS YP_002997418.1 251783115 8112434 complement(1655264..1656607) 1 NC_012891.1 similar to ATP-dependent RNA helicase [Streptococcus pyogenes MGAS10394]; ATP-dependent RNA helicase 1656607 8112434 SDEG_1721 Streptococcus dysgalactiae subsp. equisimilis GGS_124 ATP-dependent RNA helicase YP_002997418.1 1655264 R 486410 CDS YP_002997419.1 251783116 8112435 1656606..1656755 1 NC_012891.1 similar to hypothetical protein M6 Spy1410 [Streptococcus pyogenes MGAS10394]; hypothetical protein 1656755 8112435 SDEG_1722 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002997419.1 1656606 D 486410 CDS YP_002997420.1 251783117 8112436 complement(1656761..1657771) 1 NC_012891.1 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; phospho-N-acetylmuramoyl-pentapeptide- transferase 1657771 mraY 8112436 mraY Streptococcus dysgalactiae subsp. equisimilis GGS_124 phospho-N-acetylmuramoyl-pentapeptide- transferase YP_002997420.1 1656761 R 486410 CDS YP_002997421.1 251783118 8110941 complement(1657773..1660028) 1 NC_012891.1 similar to division specific DD-transpeptidase [Streptococcus pyogenes MGAS10394]; division specific D,D-transpeptidase 1660028 ftsI 8110941 ftsI Streptococcus dysgalactiae subsp. equisimilis GGS_124 division specific D,D-transpeptidase YP_002997421.1 1657773 R 486410 CDS YP_002997422.1 251783119 8111918 complement(1660032..1660385) 1 NC_012891.1 similar to cell division protein [Streptococcus pyogenes MGAS315]; cell division protein 1660385 ftsL 8111918 ftsL Streptococcus dysgalactiae subsp. equisimilis GGS_124 cell division protein YP_002997422.1 1660032 R 486410 CDS YP_002997423.1 251783120 8111920 complement(1660360..1661373) 1 NC_012891.1 similar to S-adenosyl-methyltransferase mraW [Streptococcus pyogenes MGAS10750]; S-adenosyl-methyltransferase MraW 1661373 mraW 8111920 mraW Streptococcus dysgalactiae subsp. equisimilis GGS_124 S-adenosyl-methyltransferase MraW YP_002997423.1 1660360 R 486410 CDS YP_002997424.1 251783121 8110940 complement(1661426..1661509) 1 NC_012891.1 similar to hypothetical protein M5005 Spy 1369 [Streptococcus pyogenes MGAS5005]; hypothetical protein 1661509 8110940 SDEG_1727 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002997424.1 1661426 R 486410 CDS YP_002997425.1 251783122 8112437 complement(1661609..1661782) 1 NC_012891.1 similar to hypothetical protein M6 Spy1417 [Streptococcus pyogenes MGAS10394]; hypothetical protein 1661782 8112437 SDEG_1728 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002997425.1 1661609 R 486410 CDS YP_002997426.1 251783123 8112438 complement(1661733..1661876) 1 NC_012891.1 similar to hypothetical protein MGAS10750 Spy1479 [Streptococcus pyogenes MGAS10750]; hypothetical protein 1661876 8112438 SDEG_1729 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002997426.1 1661733 R 486410 CDS YP_002997427.1 251783124 8112439 complement(1661851..1663101) 1 NC_012891.1 Catalyzes the phosphorylation of L-glutamate during the proline biosynthesis pathway; gamma-glutamyl phosphate reductase 1663101 proA 8112439 proA Streptococcus dysgalactiae subsp. equisimilis GGS_124 gamma-glutamyl phosphate reductase YP_002997427.1 1661851 R 486410 CDS YP_002997428.1 251783125 8111310 complement(1663094..1663921) 1 NC_012891.1 catalyzes the formation of glutamate 5-phosphate from glutamate in proline biosynthesis; gamma-glutamyl kinase 1663921 8111310 SDEG_1731 Streptococcus dysgalactiae subsp. equisimilis GGS_124 gamma-glutamyl kinase YP_002997428.1 1663094 R 486410 CDS YP_002997429.1 251783126 8112440 complement(1663980..1665650) 1 NC_012891.1 similar to ABC transporter permease protein [Streptococcus pyogenes MGAS10750]; ABC transporter permease 1665650 proB 8112440 proB Streptococcus dysgalactiae subsp. equisimilis GGS_124 ABC transporter permease YP_002997429.1 1663980 R 486410 CDS YP_002997430.1 251783127 8111311 complement(1665613..1666347) 1 NC_012891.1 similar to ABC transporter ATP-binding protein [Streptococcus pyogenes MGAS5005]; ABC transporter ATP-binding protein 1666347 8111311 SDEG_1733 Streptococcus dysgalactiae subsp. equisimilis GGS_124 ABC transporter ATP-binding protein YP_002997430.1 1665613 R 486410 CDS YP_002997431.1 251783128 8112441 complement(1666380..1666646) 1 NC_012891.1 similar to hypothetical protein MGAS2096 Spy1397 [Streptococcus pyogenes MGAS2096]; hypothetical protein 1666646 8112441 SDEG_1734 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002997431.1 1666380 R 486410 CDS YP_002997432.1 251783129 8112442 complement(1666839..1669028) 1 NC_012891.1 catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase; transketolase 1669028 tkt 8112442 tkt Streptococcus dysgalactiae subsp. equisimilis GGS_124 transketolase YP_002997432.1 1666839 R 486410 CDS YP_002997433.1 251783130 8110525 complement(1669042..1669686) 1 NC_012891.1 similar to novel fructose-6-phosphate aldolase from Escherichia coli; enzyme from Methanocaldococcus janaschii shows transaldolase activity; translaldolase 1669686 8110525 SDEG_1736 Streptococcus dysgalactiae subsp. equisimilis GGS_124 translaldolase YP_002997433.1 1669042 R 486410 CDS YP_002997434.1 251783131 8112443 1669355..1669729 1 NC_012891.1 similar to conserved hypothetical protein [Listeria monocytogenes str. 1/2a F6854]; hypothetical protein 1669729 8112443 SDEG_1737 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002997434.1 1669355 D 486410 CDS YP_002997435.1 251783132 8112444 complement(1669812..1671341) 1 NC_012891.1 similar to trans-acting positive regulator [Streptococcus pyogenes MGAS10750]; trans-acting positive regulator 1671341 8112444 SDEG_1738 Streptococcus dysgalactiae subsp. equisimilis GGS_124 trans-acting positive regulator YP_002997435.1 1669812 R 486410 CDS YP_002997436.1 251783133 8112445 complement(1671313..1672659) 1 NC_012891.1 similar to NADH peroxidase [Streptococcus pyogenes MGAS6180]; NADH peroxidase 1672659 8112445 SDEG_1739 Streptococcus dysgalactiae subsp. equisimilis GGS_124 NADH peroxidase YP_002997436.1 1671313 R 486410 CDS YP_002997437.1 251783134 8112446 complement(1672764..1673465) 1 NC_012891.1 similar to glycerol uptake facilitator protein [Streptococcus pyogenes MGAS10394]; glycerol uptake facilitator protein 1673465 glpF 8112446 glpF Streptococcus dysgalactiae subsp. equisimilis GGS_124 glycerol uptake facilitator protein YP_002997437.1 1672764 R 486410 CDS YP_002997438.1 251783135 8112007 complement(1673467..1675305) 1 NC_012891.1 similar to apha-glycerophosphate oxidase [Streptococcus pyogenes MGAS10394]; alpha-glycerophosphate oxidase 1675305 glpO 8112007 glpO Streptococcus dysgalactiae subsp. equisimilis GGS_124 alpha-glycerophosphate oxidase YP_002997438.1 1673467 R 486410 CDS YP_002997439.1 251783136 8112009 complement(1675321..1676835) 1 NC_012891.1 Converts glycerol and ADP to glycerol-3-phosphate and ADP; glycerol kinase 1676835 glpK 8112009 glpK Streptococcus dysgalactiae subsp. equisimilis GGS_124 glycerol kinase YP_002997439.1 1675321 R 486410 CDS YP_002997440.1 251783137 8112008 complement(1677176..1677568) 1 NC_012891.1 similar to hypothetical protein spyM18 1698 [Streptococcus pyogenes MGAS8232]; hypothetical protein 1677568 8112008 SDEG_1743 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002997440.1 1677176 R 486410 CDS YP_002997441.1 251783138 8112447 complement(1677685..1677942) 1 NC_012891.1 similar to hypothetical protein M6 Spy1431 [Streptococcus pyogenes MGAS10394]; hypothetical protein 1677942 8112447 SDEG_1744 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002997441.1 1677685 R 486410 CDS YP_002997442.1 251783139 8112448 complement(1678092..1680131) 1 NC_012891.1 glycine--tRNA ligase beta chain; glyS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; glycyl-tRNA synthetase subunit beta 1680131 glyS 8112448 glyS Streptococcus dysgalactiae subsp. equisimilis GGS_124 glycyl-tRNA synthetase subunit beta YP_002997442.1 1678092 R 486410 CDS YP_002997443.1 251783140 8112014 complement(1680374..1681291) 1 NC_012891.1 glycine--tRNA ligase alpha chain; GlyRS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; glycyl-tRNA synthetase subunit alpha 1681291 glyQ 8112014 glyQ Streptococcus dysgalactiae subsp. equisimilis GGS_124 glycyl-tRNA synthetase subunit alpha YP_002997443.1 1680374 R 486410 CDS YP_002997446.1 251783141 8112013 complement(1681663..1682217) 1 NC_012891.1 similar to hypothetical protein SPy 1691 [Streptococcus pyogenes M1 GAS]; hypothetical protein 1682217 8112013 SDEG_1749 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002997446.1 1681663 R 486410 CDS YP_002997447.1 251783142 8112449 complement(1682328..1683167) 1 NC_012891.1 similar to 2,5-diketo-D-gluconic acid reductase [Streptococcus pyogenes MGAS10270]; 2,5-diketo-D-gluconic acid reductase 1683167 8112449 SDEG_1750 Streptococcus dysgalactiae subsp. equisimilis GGS_124 2,5-diketo-D-gluconic acid reductase YP_002997447.1 1682328 R 486410 CDS YP_002997448.1 251783143 8112450 complement(1683274..1684425) 1 NC_012891.1 similar to N-acetylglucosamine-6-phosphate deacetylase [Streptococcus pyogenes str. Manfredo]; N-acetylglucosamine-6-phosphate deacetylase 1684425 nagA 8112450 nagA Streptococcus dysgalactiae subsp. equisimilis GGS_124 N-acetylglucosamine-6-phosphate deacetylase YP_002997448.1 1683274 R 486410 CDS YP_002997449.1 251783144 8111706 complement(1684542..1686191) 1 NC_012891.1 similar to sodium-dependent phosphate transporter [Streptococcus pyogenes MGAS10750]; sodium-dependent phosphate transporter 1686191 8111706 SDEG_1752 Streptococcus dysgalactiae subsp. equisimilis GGS_124 sodium-dependent phosphate transporter YP_002997449.1 1684542 R 486410 CDS YP_002997450.1 251783145 8112451 1686413..1687102 1 NC_012891.1 similar to lipoprotein [Streptococcus pyogenes str. Manfredo]; lipoprotein 1687102 8112451 SDEG_1753 Streptococcus dysgalactiae subsp. equisimilis GGS_124 lipoprotein YP_002997450.1 1686413 D 486410 CDS YP_002997451.1 251783146 8112452 complement(1687285..1688127) 1 NC_012891.1 similar to DegV family protein [Streptococcus pyogenes MGAS10394]; DegV family fatty acid binding protein 1688127 8112452 SDEG_1754 Streptococcus dysgalactiae subsp. equisimilis GGS_124 DegV family fatty acid binding protein YP_002997451.1 1687285 R 486410 CDS YP_002997452.1 251783147 8112453 1688428..1688988 1 NC_012891.1 similar to transcriptional regulator TetR family [Streptococcus pyogenes MGAS10394]; TetR family transcriptional regulator 1688988 8112453 SDEG_1755 Streptococcus dysgalactiae subsp. equisimilis GGS_124 TetR family transcriptional regulator YP_002997452.1 1688428 D 486410 CDS YP_002997453.1 251783148 8112454 complement(1689123..1690007) 1 NC_012891.1 similar to hydrolase (HAD superfamily) [Streptococcus pyogenes MGAS10394]; HAD superfamily hydrolase 1690007 8112454 SDEG_1756 Streptococcus dysgalactiae subsp. equisimilis GGS_124 HAD superfamily hydrolase YP_002997453.1 1689123 R 486410 CDS YP_002997454.1 251783149 8112455 complement(1689952..1690569) 1 NC_012891.1 similar to hypothetical membrane spanning protein [Streptococcus pyogenes MGAS10394]; hypothetical protein 1690569 8112455 SDEG_1757 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002997454.1 1689952 R 486410 CDS YP_002997455.1 251783150 8112456 complement(1690763..1691500) 1 NC_012891.1 probable ORF of C-terminal portion of tagatose 1,6-diphosphate aldolase [Streptococcus pyogenes MGAS315] resulted from mutation by unknown reason; tagatose 1,6-diphosphate aldolase 1691500 lacD.1 8112456 lacD.1 Streptococcus dysgalactiae subsp. equisimilis GGS_124 tagatose 1,6-diphosphate aldolase YP_002997455.1 1690763 R 486410 CDS YP_002997456.1 251783151 8110886 complement(1691469..1691876) 1 NC_012891.1 probable ORF of N-terminal portion of tagatose 1,6-diphosphate aldolase [Streptococcus pyogenes MGAS315] resulted from mutation by unknown reason; tagatose 1,6-diphosphate aldolase 1691876 lacD1 8110886 lacD1 Streptococcus dysgalactiae subsp. equisimilis GGS_124 tagatose 1,6-diphosphate aldolase YP_002997456.1 1691469 R 486410 CDS YP_002997457.1 251783152 8110887 complement(1691857..1692810) 1 NC_012891.1 similar to tagatose-6-phosphate kinase LacC [Streptococcus equi subsp. zooepidemicus MGCS10565]; tagatose-6-phosphate kinase 1692810 lacC 8110887 lacC Streptococcus dysgalactiae subsp. equisimilis GGS_124 tagatose-6-phosphate kinase YP_002997457.1 1691857 R 486410 CDS YP_002997458.1 251783153 8110884 complement(1692820..1693335) 1 NC_012891.1 catalyzes the interconversion of galactose 6-phosphate to tagatose 6-phosphate; galactose-6-phosphate isomerase subunit LacB 1693335 lacB1 8110884 lacB1 Streptococcus dysgalactiae subsp. equisimilis GGS_124 galactose-6-phosphate isomerase subunit LacB YP_002997458.1 1692820 R 486410 CDS YP_002997459.1 251783154 8110883 complement(1693350..1693775) 1 NC_012891.1 catalyzes the interconversion of galactose 6-phosphate to tagatose; galactose-6-phosphate isomerase subunit LacA 1693775 lacA1 8110883 lacA1 Streptococcus dysgalactiae subsp. equisimilis GGS_124 galactose-6-phosphate isomerase subunit LacA YP_002997459.1 1693350 R 486410 CDS YP_002997460.1 251783155 8110882 1693854..1694030 1 NC_012891.1 similar to transcriptional regulator [Streptococcus pyogenes MGAS2096]; transcriptional regulator 1694030 8110882 SDEG_1763 Streptococcus dysgalactiae subsp. equisimilis GGS_124 transcriptional regulator YP_002997460.1 1693854 D 486410 CDS YP_002997461.1 251783156 8112457 complement(1694033..1695484) 1 NC_012891.1 similar to sugar phosphotransferase system (PTS)galactitol-specific family IIC component [Streptococcus pyogenes str. Manfredo]; PTS system galactitol-specific family transporter subunit IIC 1695484 8112457 SDEG_1764 Streptococcus dysgalactiae subsp. equisimilis GGS_124 PTS system galactitol-specific family transporter subunit IIC YP_002997461.1 1694033 R 486410 CDS YP_002997462.1 251783157 8112458 complement(1695510..1695815) 1 NC_012891.1 similar to PTS system galactose-specific IIB component [Streptococcus pyogenes MGAS6180]; PTS system galactose-specific transporter subunit IIB 1695815 8112458 SDEG_1765 Streptococcus dysgalactiae subsp. equisimilis GGS_124 PTS system galactose-specific transporter subunit IIB YP_002997462.1 1695510 R 486410 CDS YP_002997463.1 251783158 8112459 complement(1695808..1696281) 1 NC_012891.1 similar to PTS system enzyme IIA component [Streptococcus pyogenes M1 GAS]; PTS system specific transporter subunit IIA 1696281 8112459 SDEG_1766 Streptococcus dysgalactiae subsp. equisimilis GGS_124 PTS system specific transporter subunit IIA YP_002997463.1 1695808 R 486410 CDS YP_002997464.1 251783159 8110610 1696515..1697285 1 NC_012891.1 similar to lactose phosphotransferase system repressor [Streptococcus pyogenes MGAS10394]; lactose phosphotransferase system repressor 1697285 8110610 SDEG_1767 Streptococcus dysgalactiae subsp. equisimilis GGS_124 lactose phosphotransferase system repressor YP_002997464.1 1696515 D 486410 CDS YP_002997465.1 251783160 8110611 complement(1697312..1697422) 1 NC_012891.1 similar to copper chaperone [Streptococcus pyogenes MGAS6180]; copper chaperone 1697422 8110611 SDEG_1768 Streptococcus dysgalactiae subsp. equisimilis GGS_124 copper chaperone YP_002997465.1 1697312 R 486410 CDS YP_002997466.1 251783161 8110612 complement(1697485..1697688) 1 NC_012891.1 similar to copper chaperone [Streptococcus pyogenes MGAS6180]; copper chaperone 1697688 copZ 8110612 copZ Streptococcus dysgalactiae subsp. equisimilis GGS_124 copper chaperone YP_002997466.1 1697485 R 486410 CDS YP_002997467.1 251783162 8111640 complement(1697702..1699978) 1 NC_012891.1 similar to copper-exporting ATPase [Streptococcus pyogenes MGAS2096]; copper-exporting ATPase 1699978 copA 8111640 copA Streptococcus dysgalactiae subsp. equisimilis GGS_124 copper-exporting ATPase YP_002997467.1 1697702 R 486410 CDS YP_002997468.1 251783163 8111639 complement(1699933..1700367) 1 NC_012891.1 similar to negative transcriptional regulator [Streptococcus pyogenes MGAS8232]; negative transcriptional regulator 1700367 8111639 SDEG_1771 Streptococcus dysgalactiae subsp. equisimilis GGS_124 negative transcriptional regulator YP_002997468.1 1699933 R 486410 CDS YP_002997469.1 251783164 8110613 complement(1700529..1701323) 1 NC_012891.1 similar to transposase [Streptococcus agalactiae]; transposase 1701323 8110613 SDEG_1772 Streptococcus dysgalactiae subsp. equisimilis GGS_124 transposase YP_002997469.1 1700529 R 486410 CDS YP_002997470.1 251783165 8110614 complement(1701590..1702219) 1 NC_012891.1 similar to hypothetical protein SPy 0130 [Streptococcus pyogenes M1 GAS]; hypothetical protein 1702219 8110614 SDEG_1773 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002997470.1 1701590 R 486410 CDS YP_002997471.1 251783166 8110615 complement(1702228..1702497) 1 NC_012891.1 similar to hypothetical protein SPy 0129 [Streptococcus pyogenes M1 GAS]; hypothetical protein 1702497 8110615 SDEG_1774 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002997471.1 1702228 R 486410 CDS YP_002997472.1 251783167 8110616 1702647..1703579 1 NC_012891.1 similar to transposase IS256 family [Streptococcus agalactiae 2603V/R]; IS256 family transposase 1703579 8110616 SDEG_1775 Streptococcus dysgalactiae subsp. equisimilis GGS_124 IS256 family transposase YP_002997472.1 1702647 D 486410 CDS YP_002997473.1 251783168 8110617 1703585..1703821 1 NC_012891.1 similar to transposase IS256 family [Streptococcus agalactiae 2603V/R]; IS256 family transposase 1703821 8110617 SDEG_1776 Streptococcus dysgalactiae subsp. equisimilis GGS_124 IS256 family transposase YP_002997473.1 1703585 D 486410 CDS YP_002997474.1 251783169 8110618 complement(1704055..1704744) 1 NC_012891.1 similar to hypothetical protein MGAS2096 Spy0117 [Streptococcus pyogenes MGAS2096]; hypothetical protein 1704744 8110618 SDEG_1777 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002997474.1 1704055 R 486410 CDS YP_002997475.1 251783170 8110619 complement(1704674..1705393) 1 NC_012891.1 similar to sortase B family protein [Streptococcus pyogenes MGAS2096]; sortase 1705393 eftLSL-B 8110619 eftLSL-B Streptococcus dysgalactiae subsp. equisimilis GGS_124 sortase YP_002997475.1 1704674 R 486410 CDS YP_002997476.1 251783171 8111867 complement(1705416..1706462) 1 NC_012891.1 similar to hypothetical protein M28 Spy0109 [Streptococcus pyogenes MGAS6180]; hypothetical protein 1706462 8111867 SDEG_1779 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002997476.1 1705416 R 486410 CDS YP_002997477.1 251783172 8110620 complement(1706483..1707004) 1 NC_012891.1 similar to signal peptidase I [Streptococcus pyogenes MGAS6180]; signal peptidase I 1707004 8110620 SDEG_1780 Streptococcus dysgalactiae subsp. equisimilis GGS_124 signal peptidase I YP_002997477.1 1706483 R 486410 CDS YP_002997478.1 251783173 8110621 complement(1706997..1708523) 1 NC_012891.1 similar to collagen binding protein [Streptococcus pyogenes MGAS315]; collagen binding protein 1708523 cbp 8110621 cbp Streptococcus dysgalactiae subsp. equisimilis GGS_124 collagen binding protein YP_002997478.1 1706997 R 486410 CDS YP_002997479.1 251783174 8111607 complement(1708520..1709647) 1 NC_012891.1 similar to transcriptional regulator AraC family [Streptococcus equi subsp.zooepidemicus MGCS10565]; hypothetical protein 1709647 8111607 SDEG_1782 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002997479.1 1708520 R 486410 CDS YP_002997480.1 251783175 8110622 complement(1709999..1710286) 1 NC_012891.1 similar to ISSdy1 transposase OrfB [Streptococcus agalactiae 2603V/R]; ISSdy1, transposase OrfB 1710286 8110622 SDEG_1783 Streptococcus dysgalactiae subsp. equisimilis GGS_124 ISSdy1, transposase OrfB YP_002997480.1 1709999 R 486410 CDS YP_002997481.1 251783176 8110623 complement(1710378..1710779) 1 NC_012891.1 similar to ISSdy1 transposase OrfB [Streptococcus agalactiae 2603V/R]; ISSdy1, transposase OrfB 1710779 8110623 SDEG_1784 Streptococcus dysgalactiae subsp. equisimilis GGS_124 ISSdy1, transposase OrfB YP_002997481.1 1710378 R 486410 CDS YP_002997482.1 251783177 8110624 complement(1710815..1711105) 1 NC_012891.1 similar to hypothetical protein gbs1310 [Streptococcus agalactiae NEM316]; hypothetical protein 1711105 8110624 SDEG_1785 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002997482.1 1710815 R 486410 CDS YP_002997483.1 251783178 8110625 complement(1711366..1712169) 1 NC_012891.1 similar to transposase [Lactococcus lactis subsp. cremoris SK11]; transposase 1712169 8110625 SDEG_1786 Streptococcus dysgalactiae subsp. equisimilis GGS_124 transposase YP_002997483.1 1711366 R 486410 CDS YP_002997484.1 251783179 8110626 1712344..1713336 1 NC_012891.1 similar to esterase [Streptococcus pyogenes MGAS2096]; esterase 1713336 8110626 SDEG_1787 Streptococcus dysgalactiae subsp. equisimilis GGS_124 esterase YP_002997484.1 1712344 D 486410 CDS YP_002997485.1 251783180 8110627 complement(1713471..1713821) 1 NC_012891.1 associates with free 30S ribosomal subunits; essential for efficient processing of 16S rRNA; in Escherichia coli rbfA is induced by cold shock; ribosome-binding factor A 1713821 rbfA 8110627 rbfA Streptococcus dysgalactiae subsp. equisimilis GGS_124 ribosome-binding factor A YP_002997485.1 1713471 R 486410 CDS YP_002997486.1 251783181 8111350 complement(1714027..1716924) 1 NC_012891.1 Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; translation initiation factor IF-2 1716924 infB 8111350 infB Streptococcus dysgalactiae subsp. equisimilis GGS_124 translation initiation factor IF-2 YP_002997486.1 1714027 R 486410 CDS YP_002997487.1 251783182 8112052 complement(1716944..1717246) 1 NC_012891.1 similar to LSU ribosomal protein L7AE [Streptococcus pyogenes MGAS10750]; hypothetical protein 1717246 8112052 SDEG_1790 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002997487.1 1716944 R 486410 CDS YP_002997488.1 251783183 8110628 complement(1717239..1717538) 1 NC_012891.1 similar to hypothetical cytosolic protein [Streptococcus pyogenes MGAS10394]; hypothetical protein 1717538 8110628 SDEG_1791 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002997488.1 1717239 R 486410 CDS YP_002997489.1 251783184 8110629 complement(1717551..1718765) 1 NC_012891.1 modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination; transcription elongation factor NusA 1718765 nusA 8110629 nusA Streptococcus dysgalactiae subsp. equisimilis GGS_124 transcription elongation factor NusA YP_002997489.1 1717551 R 486410 CDS YP_002997490.1 251783185 8111725 complement(1718851..1719300) 1 NC_012891.1 in Streptococcus pneumoniae this gene was found to be essential; structure determination of the Streptococcus protein shows that it is similar to a number of other proteins; hypothetical protein 1719300 8111725 SDEG_1793 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002997490.1 1718851 R 486410 CDS YP_002997491.1 251783186 8110631 complement(1719828..1720463) 1 NC_012891.1 tRNA (guanine-N(7)-)-methyltransferase; catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA by transferring the methyl residue from S-adenosyl-L-methionine; tRNA (guanine-N(7)-)-methyltransferase 1720463 trmB 8110631 trmB Streptococcus dysgalactiae subsp. equisimilis GGS_124 tRNA (guanine-N(7)-)-methyltransferase YP_002997491.1 1719828 R 486410 CDS YP_002997492.1 251783187 8111925 complement(1720463..1721254) 1 NC_012891.1 similar to phosphotransferase enzyme family protein [Streptococcus pyogenes str. Manfredo]; phosphotransferase 1721254 8111925 SDEG_1796 Streptococcus dysgalactiae subsp. equisimilis GGS_124 phosphotransferase YP_002997492.1 1720463 R 486410 CDS YP_002997493.1 251783188 8110632 complement(1721319..1722353) 1 NC_012891.1 similar to protein ecsB [Streptococcus pyogenes MGAS10270]; ABC transporter 1722353 ecsB 8110632 ecsB Streptococcus dysgalactiae subsp. equisimilis GGS_124 ABC transporter YP_002997493.1 1721319 R 486410 CDS YP_002997494.1 251783189 8111865 complement(1722356..1723081) 1 NC_012891.1 similar to ABC transporter (ATP-binding protein) [Streptococcus pyogenes M1 GAS]; ABC transporter ATP-binding protein 1723081 ecsA 8111865 ecsA Streptococcus dysgalactiae subsp. equisimilis GGS_124 ABC transporter ATP-binding protein YP_002997494.1 1722356 R 486410 CDS YP_002997495.1 251783190 8111864 1723153..1723572 1 NC_012891.1 similar to cell-cycle regulation histidine triad protein HIT [Streptococcus equi subsp. zooepidemicus MGCS10565]; cell-cycle regulation histidine triad protein HIT 1723572 hit 8111864 hit Streptococcus dysgalactiae subsp. equisimilis GGS_124 cell-cycle regulation histidine triad protein HIT YP_002997495.1 1723153 D 486410 CDS YP_002997496.1 251783191 8112033 1723569..1723898 1 NC_012891.1 similar to COG0840, methyl-accepting chemotaxis protein [Streptococcus pyogenes M49 591]; COG0840: methyl-accepting chemotaxis protein 1723898 8112033 SDEG_1800 Streptococcus dysgalactiae subsp. equisimilis GGS_124 COG0840: methyl-accepting chemotaxis protein YP_002997496.1 1723569 D 486410 CDS YP_002997497.1 251783192 8110633 complement(1724056..1725354) 1 NC_012891.1 similar to transcriptional regulator LytR family [Streptococcus pyogenes MGAS10394]; LytR family transcriptional regulator 1725354 8110633 SDEG_1801 Streptococcus dysgalactiae subsp. equisimilis GGS_124 LytR family transcriptional regulator YP_002997497.1 1724056 R 486410 CDS YP_002997498.1 251783193 8110634 complement(1725336..1725857) 1 NC_012891.1 similar to acetyltransferase [Streptococcus pyogenes MGAS5005]; acetyltransferase 1725857 8110634 SDEG_1802 Streptococcus dysgalactiae subsp. equisimilis GGS_124 acetyltransferase YP_002997498.1 1725336 R 486410 CDS YP_002997499.1 251783194 8110635 complement(1725850..1726299) 1 NC_012891.1 similar to ATP/GTP hydrolase [Streptococcus pyogenes MGAS10394]; ATP/GTP hydrolase 1726299 8110635 SDEG_1803 Streptococcus dysgalactiae subsp. equisimilis GGS_124 ATP/GTP hydrolase YP_002997499.1 1725850 R 486410 CDS YP_002997500.1 251783195 8110636 complement(1726470..1727930) 1 NC_012891.1 similar to guanine-hypoxanthine permease [Streptococcus equi subsp. zooepidemicus MGCS10565]; guanine-hypoxanthine permease 1727930 8110636 SDEG_1804 Streptococcus dysgalactiae subsp. equisimilis GGS_124 guanine-hypoxanthine permease YP_002997500.1 1726470 R 486410 CDS YP_002997501.1 251783196 8110637 1728191..1729003 1 NC_012891.1 similar to hydrolase HAD superfamily [Streptococcus pyogenes MGAS5005]; HAD superfamily hydrolase 1729003 8110637 SDEG_1805 Streptococcus dysgalactiae subsp. equisimilis GGS_124 HAD superfamily hydrolase YP_002997501.1 1728191 D 486410 CDS YP_002997502.1 251783197 8110638 1729356..1730348 1 NC_012891.1 similar to PTS system mannose-specific IIAB component [Streptococcus pyogenes MGAS5005]; PTS system mannose-specific transporter subunit IIAB 1730348 manL 8110638 manL Streptococcus dysgalactiae subsp. equisimilis GGS_124 PTS system mannose-specific transporter subunit IIAB YP_002997502.1 1729356 D 486410 CDS YP_002997503.1 251783198 8110928 1730434..1731243 1 NC_012891.1 similar to PTS system mannose-specific IIC component [Streptococcus pyogenes MGAS5005]; PTS system mannose-specific transporter subunit IIC 1731243 manM 8110928 manM Streptococcus dysgalactiae subsp. equisimilis GGS_124 PTS system mannose-specific transporter subunit IIC YP_002997503.1 1730434 D 486410 CDS YP_002997504.1 251783199 8110929 1731260..1732171 1 NC_012891.1 similar to PTS system mannose-specific IID component [Streptococcus pyogenes MGAS5005]; PTS system mannose-specific transporter subunit IID 1732171 manN 8110929 manN Streptococcus dysgalactiae subsp. equisimilis GGS_124 PTS system mannose-specific transporter subunit IID YP_002997504.1 1731260 D 486410 CDS YP_002997505.1 251783200 8110930 1732285..1732659 1 NC_012891.1 similar to hypothetical cytosolic protein [Streptococcus pyogenes MGAS5005]; hypothetical protein 1732659 manO 8110930 manO Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002997505.1 1732285 D 486410 CDS YP_002997506.1 251783201 8110931 complement(1732766..1733833) 1 NC_012891.1 similar to hypothetical protein Sez 0419 [Streptococcus equi subsp. zooepidemicus MGCS10565]; hypothetical protein 1733833 8110931 SDEG_1810 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002997506.1 1732766 R 486410 CDS YP_002997507.1 251783202 8110639 1734256..1735533 1 NC_012891.1 catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; seryl-tRNA synthetase 1735533 serS 8110639 serS Streptococcus dysgalactiae subsp. equisimilis GGS_124 seryl-tRNA synthetase YP_002997507.1 1734256 D 486410 CDS YP_002997508.1 251783203 8110482 complement(1735767..1736537) 1 NC_012891.1 catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer composed of two alpha (AccA) and two beta (AccD) subunits; one of the two catalytic subunits that can form the acetyl CoA carboxylase enzyme together with a carrier protein; these proteins present a shorter N-terminus; acetyl-CoA carboxylase subunit alpha 1736537 accD 8110482 accD Streptococcus dysgalactiae subsp. equisimilis GGS_124 acetyl-CoA carboxylase subunit alpha YP_002997508.1 1735767 R 486410 CDS YP_002997509.1 251783204 8110852 complement(1736534..1737400) 1 NC_012891.1 catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer of AccA2D2 subunits; acetyl-CoA carboxylase subunit beta 1737400 accA 8110852 accA Streptococcus dysgalactiae subsp. equisimilis GGS_124 acetyl-CoA carboxylase subunit beta YP_002997509.1 1736534 R 486410 CDS YP_002997510.1 251783205 8110849 complement(1737409..1738773) 1 NC_012891.1 an AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism; acetyl-CoA carboxylase biotin carboxylase subunit 1738773 accC 8110849 accC Streptococcus dysgalactiae subsp. equisimilis GGS_124 acetyl-CoA carboxylase biotin carboxylase subunit YP_002997510.1 1737409 R 486410 CDS YP_002997511.1 251783206 8110851 complement(1738805..1739227) 1 NC_012891.1 similar to (3R)-hydroxymyristoyl ACP dehydratase [Streptococcus pyogenes MGAS10394]; (3R)-hydroxymyristoyl-ACP dehydratase 1739227 fabZ 8110851 fabZ Streptococcus dysgalactiae subsp. equisimilis GGS_124 (3R)-hydroxymyristoyl-ACP dehydratase YP_002997511.1 1738805 R 486410 CDS YP_002997512.1 251783207 8111880 complement(1739224..1739724) 1 NC_012891.1 composes the biotin carboxyl carrier protein subunit of the acetyl-CoA carboxylase complex, the enzyme that catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, which in turn controls the rate of fatty acid metabolism; acetyl-CoA carboxylase biotin carboxyl carrier protein subunit 1739724 accB 8111880 accB Streptococcus dysgalactiae subsp. equisimilis GGS_124 acetyl-CoA carboxylase biotin carboxyl carrier protein subunit YP_002997512.1 1739224 R 486410 CDS YP_002997513.1 251783208 8110850 complement(1739726..1740958) 1 NC_012891.1 FabF; beta-ketoacyl-ACP synthase II, KASII; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP; 3-oxoacyl-(acyl carrier protein) synthase II 1740958 fabF 8110850 fabF Streptococcus dysgalactiae subsp. equisimilis GGS_124 3-oxoacyl-(acyl carrier protein) synthase II YP_002997513.1 1739726 R 486410 CDS YP_002997514.1 251783209 8111876 complement(1740973..1741707) 1 NC_012891.1 catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis; 3-ketoacyl-ACP reductase 1741707 fabG 8111876 fabG Streptococcus dysgalactiae subsp. equisimilis GGS_124 3-ketoacyl-ACP reductase YP_002997514.1 1740973 R 486410 CDS YP_002997515.1 251783210 8111877 complement(1741719..1742645) 1 NC_012891.1 similar to acyl-carrier-protein S-malonyltransferase [Streptococcus pyogenes SSI-1]; ACP S-malonyltransferase 1742645 fabD 8111877 fabD Streptococcus dysgalactiae subsp. equisimilis GGS_124 ACP S-malonyltransferase YP_002997515.1 1741719 R 486410 CDS YP_002997516.1 251783211 8111875 complement(1742664..1743635) 1 NC_012891.1 similar to enoyl-[acyl-carrier protein] reductase (NADH) [Streptococcus pyogenes MGAS5005]; enoyl-ACP reductase 1743635 fabK 8111875 fabK Streptococcus dysgalactiae subsp. equisimilis GGS_124 enoyl-ACP reductase YP_002997516.1 1742664 R 486410 CDS YP_002997517.1 251783212 8111879 complement(1743834..1744058) 1 NC_012891.1 carries the fatty acid chain in fatty acid biosynthesis; acyl carrier protein 1744058 acpP 8111879 acpP Streptococcus dysgalactiae subsp. equisimilis GGS_124 acyl carrier protein YP_002997517.1 1743834 R 486410 CDS YP_002997518.1 251783213 8112303 complement(1744119..1745093) 1 NC_012891.1 FabH; beta-ketoacyl-acyl carrier protein synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs; 3-oxoacyl-ACP synthase 1745093 fabH 8112303 fabH Streptococcus dysgalactiae subsp. equisimilis GGS_124 3-oxoacyl-ACP synthase YP_002997518.1 1744119 R 486410 CDS YP_002997519.1 251783214 8111878 complement(1745094..1745546) 1 NC_012891.1 similar to transcriptional regulator MarR family [Streptococcus pyogenes MGAS6180]; MarR family transcriptional regulator 1745546 8111878 SDEG_1823 Streptococcus dysgalactiae subsp. equisimilis GGS_124 MarR family transcriptional regulator YP_002997519.1 1745094 R 486410 CDS YP_002997520.1 251783215 8110640 complement(1745605..1746396) 1 NC_012891.1 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; enoyl-CoA hydratase 1746396 phaB 8110640 phaB Streptococcus dysgalactiae subsp. equisimilis GGS_124 enoyl-CoA hydratase YP_002997520.1 1745605 R 486410 CDS YP_002997521.1 251783216 8111289 complement(1746618..1747769) 1 NC_012891.1 chaperone Hsp40; co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion; chaperone protein DnaJ 1747769 dnaJ 8111289 dnaJ Streptococcus dysgalactiae subsp. equisimilis GGS_124 chaperone protein DnaJ YP_002997521.1 1746618 R 486410 CDS YP_002997522.1 251783217 8111848 complement(1747939..1748580) 1 NC_012891.1 similar to 4-methyl-5(beta-hydroxyethyl)-thiazole monophosphate synthesis protein [Streptococcus gordonii str. Challis substr. CH1]; 4-methyl-5(beta-hydroxyethyl)-thiazole monophosphate synthesis protein 1748580 thiJ-2 8111848 thiJ-2 Streptococcus dysgalactiae subsp. equisimilis GGS_124 4-methyl-5(beta-hydroxyethyl)-thiazole monophosphate synthesis protein YP_002997522.1 1747939 R 486410 CDS YP_002997523.1 251783218 8110518 complement(1748848..1750674) 1 NC_012891.1 heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria; molecular chaperone DnaK 1750674 dnaK 8110518 dnaK Streptococcus dysgalactiae subsp. equisimilis GGS_124 molecular chaperone DnaK YP_002997523.1 1748848 R 486410 CDS YP_002997524.1 251783219 8111849 1750472..1750693 1 NC_012891.1 similar to hypothetical protein FN0115 [Fusobacterium nucleatum subsp. nucleatum ATCC 25586]; hypothetical protein 1750693 8111849 SDEG_1828 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002997524.1 1750472 D 486410 CDS YP_002997525.1 251783220 8110641 complement(1750792..1751334) 1 NC_012891.1 with DnaK and DnaJ acts in response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins; may act as a thermosensor; heat shock protein GrpE 1751334 grpE 8110641 grpE Streptococcus dysgalactiae subsp. equisimilis GGS_124 heat shock protein GrpE YP_002997525.1 1750792 R 486410 CDS YP_002997526.1 251783221 8112021 complement(1751376..1752410) 1 NC_012891.1 Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons; heat-inducible transcription repressor 1752410 hrcA 8112021 hrcA Streptococcus dysgalactiae subsp. equisimilis GGS_124 heat-inducible transcription repressor YP_002997526.1 1751376 R 486410 CDS YP_002997527.1 251783222 8112037 complement(1752545..1753114) 1 NC_012891.1 similar to N-acetyl-muramidase [Streptococcus pyogenes MGAS8232]; N-acetyl-muramidase 1753114 8112037 SDEG_1831 Streptococcus dysgalactiae subsp. equisimilis GGS_124 N-acetyl-muramidase YP_002997527.1 1752545 R 486410 CDS YP_002997528.1 251783223 8110642 complement(1753111..1753854) 1 NC_012891.1 similar to DD-carboxypeptidase [Streptococcus pyogenes MGAS8232]; D,D-carboxypeptidase 1753854 8110642 SDEG_1832 Streptococcus dysgalactiae subsp. equisimilis GGS_124 D,D-carboxypeptidase YP_002997528.1 1753111 R 486410 CDS YP_002997529.1 251783224 8110643 complement(1753844..1754563) 1 NC_012891.1 similar to phosphoglycerate mutase [Streptococcus pyogenes MGAS10394]; phosphoglycerate mutase 1754563 8110643 SDEG_1833 Streptococcus dysgalactiae subsp. equisimilis GGS_124 phosphoglycerate mutase YP_002997529.1 1753844 R 486410 CDS YP_002997530.1 251783225 8110644 complement(1754857..1755099) 1 NC_012891.1 similar to hypothetical membrane spanning protein [Streptococcus pyogenes MGAS10394]; hypothetical protein 1755099 8110644 SDEG_1834 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002997530.1 1754857 R 486410 CDS YP_002997531.1 251783226 8110645 complement(1755164..1756105) 1 NC_012891.1 similar to drug/metabolite transporter (DMT) superfamily protein [Streptococcus equi subsp. zooepidemicus MGCS10565]; drug/metabolite transporter superfamily protein 1756105 8110645 SDEG_1835 Streptococcus dysgalactiae subsp. equisimilis GGS_124 drug/metabolite transporter superfamily protein YP_002997531.1 1755164 R 486410 CDS YP_002997532.1 251783227 8110646 complement(1756271..1757404) 1 NC_012891.1 similar to transposase [Streptococcus pyogenes MGAS5005]; transposase 1757404 8110646 SDEG_1836 Streptococcus dysgalactiae subsp. equisimilis GGS_124 transposase YP_002997532.1 1756271 R 486410 CDS YP_002997533.1 251783228 8110647 complement(1757654..1759093) 1 NC_012891.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; aspartyl/glutamyl-tRNA amidotransferase subunit B 1759093 gatB 8110647 gatB Streptococcus dysgalactiae subsp. equisimilis GGS_124 aspartyl/glutamyl-tRNA amidotransferase subunit B YP_002997533.1 1757654 R 486410 CDS YP_002997534.1 251783229 8111987 complement(1759093..1760559) 1 NC_012891.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; aspartyl/glutamyl-tRNA amidotransferase subunit A 1760559 gatA 8111987 gatA Streptococcus dysgalactiae subsp. equisimilis GGS_124 aspartyl/glutamyl-tRNA amidotransferase subunit A YP_002997534.1 1759093 R 486410 CDS YP_002997535.1 251783230 8111986 complement(1760559..1760873) 1 NC_012891.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; some Mycoplasma proteins contain an N-terminal fusion to an unknown domain; aspartyl/glutamyl-tRNA amidotransferase subunit C 1760873 gatC 8111986 gatC Streptococcus dysgalactiae subsp. equisimilis GGS_124 aspartyl/glutamyl-tRNA amidotransferase subunit C YP_002997535.1 1760559 R 486410 CDS YP_002997536.1 251783231 8111988 complement(1761093..1763738) 1 NC_012891.1 catalyzes the formation of phosphoenolpyruvate from pyruvate; pyruvate phosphate dikinase 1763738 8111988 SDEG_1840 Streptococcus dysgalactiae subsp. equisimilis GGS_124 pyruvate phosphate dikinase YP_002997536.1 1761093 R 486410 CDS YP_002997537.1 251783232 8110648 complement(1763752..1764591) 1 NC_012891.1 similar to hypothetical protein SAG1671 [Streptococcus agalactiae 2603V/R]; hypothetical protein 1764591 8110648 SDEG_1841 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002997537.1 1763752 R 486410 CDS YP_002997538.1 251783233 8110649 complement(1764612..1765115) 1 NC_012891.1 similar to hypothetical protein [Streptococcus agalactiae 2603V/R]; hypothetical protein 1765115 8110649 SDEG_1842 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002997538.1 1764612 R 486410 CDS YP_002997539.1 251783234 8110650 complement(1765436..1765735) 1 NC_012891.1 similar to hypothetical protein STRINF 01222 [Streptococcus infantarius subsp. infantarius ATCC BAA-102]; hypothetical protein 1765735 8110650 SDEG_1843 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002997539.1 1765436 R 486410 CDS YP_002997540.1 251783235 8110651 complement(1765728..1767380) 1 NC_012891.1 similar to hypothetical protein STRINF 01221 [Streptococcus infantarius subsp. infantarius ATCC BAA-102]; hypothetical protein 1767380 8110651 SDEG_1844 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002997540.1 1765728 R 486410 CDS YP_002997541.1 251783236 8110652 complement(1767398..1767736) 1 NC_012891.1 similar to rhodanese-like [Enterococcus faecium DO]; rhodanese-like protein 1767736 8110652 SDEG_1845 Streptococcus dysgalactiae subsp. equisimilis GGS_124 rhodanese-like protein YP_002997541.1 1767398 R 486410 CDS YP_002997542.1 251783237 8110653 1767950..1768210 1 NC_012891.1 similar to hypothetical protein STRINF 01219 [Streptococcus infantarius subsp. infantarius ATCC BAA-102]; hypothetical protein 1768210 8110653 SDEG_1846 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002997542.1 1767950 D 486410 CDS YP_002997543.1 251783238 8110654 complement(1768277..1768825) 1 NC_012891.1 nicotinamidase; pyrazinamidase 1768825 8110654 SDEG_1847 Streptococcus dysgalactiae subsp. equisimilis GGS_124 pyrazinamidase YP_002997543.1 1768277 R 486410 CDS YP_002997544.1 251783239 8110655 complement(1768966..1769748) 1 NC_012891.1 CodY; DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase (By similarity). It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor; transcriptional repressor CodY 1769748 codY 8110655 codY Streptococcus dysgalactiae subsp. equisimilis GGS_124 transcriptional repressor CodY YP_002997544.1 1768966 R 486410 CDS YP_002997545.1 251783240 8111631 complement(1770013..1771227) 1 NC_012891.1 broad specificity; family IV; in Corynebacterium glutamicum this protein can use glutamate, 2-aminobutyrate, and aspartate as amino donors and pyruvate as the acceptor; aminotransferase AlaT 1771227 alaT 8111631 alaT Streptococcus dysgalactiae subsp. equisimilis GGS_124 aminotransferase AlaT YP_002997545.1 1770013 R 486410 CDS YP_002997546.1 251783241 8112320 1771564..1772016 1 NC_012891.1 similar to universal stress protein family [Streptococcus pyogenes MGAS6180]; universal stress protein family 1772016 8112320 SDEG_1850 Streptococcus dysgalactiae subsp. equisimilis GGS_124 universal stress protein family YP_002997546.1 1771564 D 486410 CDS YP_002997547.1 251783242 8110656 complement(1772179..1773567) 1 NC_012891.1 similar to hydrolase (HAD superfamily) [Streptococcus equi subsp. zooepidemicus MGCS10565]; HAD superfamily hydrolase 1773567 8110656 SDEG_1851 Streptococcus dysgalactiae subsp. equisimilis GGS_124 HAD superfamily hydrolase YP_002997547.1 1772179 R 486410 CDS YP_002997548.1 251783243 8110657 1773640..1774605 1 NC_012891.1 similar to L-asparaginase [Streptococcus pyogenes M1 GAS]; L-asparaginase 1774605 asnB 8110657 asnB Streptococcus dysgalactiae subsp. equisimilis GGS_124 L-asparaginase YP_002997548.1 1773640 D 486410 CDS YP_002997549.1 251783244 8112349 complement(1774655..1775572) 1 NC_012891.1 similar to oxidoreductase aldo/keto reductase family [Streptococcus agalactiae 2603V/R]; oxidoreductase, aldo/keto reductase family 1775572 8112349 SDEG_1853 Streptococcus dysgalactiae subsp. equisimilis GGS_124 oxidoreductase, aldo/keto reductase family YP_002997549.1 1774655 R 486410 CDS YP_002997550.1 251783245 8110658 complement(1775769..1777799) 1 NC_012891.1 similar to ATP-dependent DNA helicase RecG [Streptococcus equi subsp. zooepidemicus MGCS10565]; ATP-dependent DNA helicase RecG 1777799 recG 8110658 recG Streptococcus dysgalactiae subsp. equisimilis GGS_124 ATP-dependent DNA helicase RecG YP_002997550.1 1775769 R 486410 CDS YP_002997551.1 251783246 8111034 complement(1777885..1779360) 1 NC_012891.1 similar to Cobalt transport ATP-binding protein cbiO [Streptococcus pyogenes MGAS2096]; cobalt transport ATP-binding protein cbiO 1779360 cbiO 8111034 cbiO Streptococcus dysgalactiae subsp. equisimilis GGS_124 cobalt transport ATP-binding protein cbiO YP_002997551.1 1777885 R 486410 CDS YP_002997552.1 251783247 8111605 complement(1779276..1779956) 1 NC_012891.1 similar to cobalt transport protein cbiQ [Streptococcus pyogenes MGAS5005]; cobalt transport protein cbiQ 1779956 cbiQ 8111605 cbiQ Streptococcus dysgalactiae subsp. equisimilis GGS_124 cobalt transport protein cbiQ YP_002997552.1 1779276 R 486410 CDS YP_002997553.1 251783248 8111606 complement(1779953..1780546) 1 NC_012891.1 similar to hypothetical protein SpyM3 1555 [Streptococcus pyogenes MGAS315]; hypothetical protein 1780546 8111606 SDEG_1857 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002997553.1 1779953 R 486410 CDS YP_002997554.1 251783249 8110659 complement(1780543..1782246) 1 NC_012891.1 similar to ABC transporter ATP-binding protein [Streptococcus pyogenes MGAS10270]; ABC transporter ATP-binding protein 1782246 8110659 SDEG_1858 Streptococcus dysgalactiae subsp. equisimilis GGS_124 ABC transporter ATP-binding protein YP_002997554.1 1780543 R 486410 CDS YP_002997555.1 251783250 8110660 complement(1782206..1783969) 1 NC_012891.1 similar to ABC transporter (ATP-binding protein) [Streptococcus pyogenes MGAS8232]; ABC transporter ATP-binding protein 1783969 8110660 SDEG_1859 Streptococcus dysgalactiae subsp. equisimilis GGS_124 ABC transporter ATP-binding protein YP_002997555.1 1782206 R 486410 CDS YP_002997556.1 251783251 8110661 complement(1783982..1784803) 1 NC_012891.1 similar to ferrichrome transport ATP-binding protein [Streptococcus pyogenes MGAS6180]; ferrichrome transport ATP-binding protein 1784803 fhuC 8110661 fhuC Streptococcus dysgalactiae subsp. equisimilis GGS_124 ferrichrome transport ATP-binding protein YP_002997556.1 1783982 R 486410 CDS YP_002997557.1 251783252 8111895 complement(1784800..1785822) 1 NC_012891.1 similar to ferrichrome transport system permease protein [Streptococcus pyogenes MGAS10394]; ferrichrome transport system permease 1785822 fhuB 8111895 fhuB Streptococcus dysgalactiae subsp. equisimilis GGS_124 ferrichrome transport system permease YP_002997557.1 1784800 R 486410 CDS YP_002997558.1 251783253 8111894 complement(1785824..1786747) 1 NC_012891.1 similar to ferrichrome-binding protein [Streptococcus pyogenes MGAS10750]; ferrichrome-binding protein 1786747 8111894 SDEG_1862 Streptococcus dysgalactiae subsp. equisimilis GGS_124 ferrichrome-binding protein YP_002997558.1 1785824 R 486410 CDS YP_002997559.1 251783254 8110662 complement(1786692..1787573) 1 NC_012891.1 similar to hypothetical protein MGAS10270 Spy1597 [Streptococcus pyogenes MGAS10270]; hypothetical protein 1787573 shp 8110662 shp Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002997559.1 1786692 R 486410 CDS YP_002997560.1 251783255 8110483 complement(1787788..1791525) 1 NC_012891.1 similar to Fe3+-siderophore transport protein [Streptococcus pyogenes MGAS10750]; Fe3+-siderophore transport protein 1791525 8110483 SDEG_1864 Streptococcus dysgalactiae subsp. equisimilis GGS_124 Fe3+-siderophore transport protein YP_002997560.1 1787788 R 486410 CDS YP_002997561.1 251783256 8110663 complement(1791814..1793289) 1 NC_012891.1 similar to immunogenic secreted protein [Streptococcus pyogenes MGAS6180]; immunogenic secreted protein 1793289 isp2 8110663 isp2 Streptococcus dysgalactiae subsp. equisimilis GGS_124 immunogenic secreted protein YP_002997561.1 1791814 R 486410 CDS YP_002997562.1 251783257 8110874 complement(1793379..1794479) 1 NC_012891.1 converts L-alanine to D-alanine which is used in cell wall biosynthesis; binds one pyridoxal phosphate per monomer; forms a homodimer; alanine racemase 1794479 alr 8110874 alr Streptococcus dysgalactiae subsp. equisimilis GGS_124 alanine racemase YP_002997562.1 1793379 R 486410 CDS YP_002997563.1 251783258 8112305 complement(1794476..1794832) 1 NC_012891.1 Catalyzes the formation of holo-ACP, which mediates the essential transfer of acyl fatty acid intermediates during the biosynthesis of fatty acids and lipids; 4'-phosphopantetheinyl transferase 1794832 acpS 8112305 acpS Streptococcus dysgalactiae subsp. equisimilis GGS_124 4'-phosphopantetheinyl transferase YP_002997563.1 1794476 R 486410 CDS YP_002997564.1 251783259 8112306 complement(1794953..1797481) 1 NC_012891.1 functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond SecA1; SecA2 is not essential and seems to play a role in secretion of a subset of proteins; preprotein translocase subunit SecA 1797481 secA 8112306 secA Streptococcus dysgalactiae subsp. equisimilis GGS_124 preprotein translocase subunit SecA YP_002997564.1 1794953 R 486410 CDS YP_002997565.1 251783260 8110477 complement(1797617..1798570) 1 NC_012891.1 similar to mannose-6-phosphate isomerase [Streptococcus pyogenes str. Manfredo]; mannose-6-phosphate isomerase 1798570 manA 8110477 manA Streptococcus dysgalactiae subsp. equisimilis GGS_124 mannose-6-phosphate isomerase YP_002997565.1 1797617 R 486410 CDS YP_002997566.1 251783261 8110927 complement(1798664..1799548) 1 NC_012891.1 similar to fructokinase [Streptococcus pyogenes MGAS10750]; fructokinase 1799548 scrK 8110927 scrK Streptococcus dysgalactiae subsp. equisimilis GGS_124 fructokinase YP_002997566.1 1798664 R 486410 CDS YP_002997567.1 251783262 8110471 complement(1799734..1801617) 1 NC_012891.1 similar to PTS system sucrose-specific IIABC component [Streptococcus pyogenes MGAS5005]; PTS system sucrose-specific transporter subunit IIABC 1801617 scrA 8110471 scrA Streptococcus dysgalactiae subsp. equisimilis GGS_124 PTS system sucrose-specific transporter subunit IIABC YP_002997567.1 1799734 R 486410 CDS YP_002997568.1 251783263 8110469 1801860..1803299 1 NC_012891.1 similar to sucrose-6-phosphate hydrolase [Streptococcus pyogenes MGAS10394]; sucrose-6-phosphate hydrolase 1803299 scrB 8110469 scrB Streptococcus dysgalactiae subsp. equisimilis GGS_124 sucrose-6-phosphate hydrolase YP_002997568.1 1801860 D 486410 CDS YP_002997569.1 251783264 8110470 1803304..1804269 1 NC_012891.1 similar to sucrose operon repressor [Streptococcus pyogenes MGAS5005]; sucrose operon repressor 1804269 scrR 8110470 scrR Streptococcus dysgalactiae subsp. equisimilis GGS_124 sucrose operon repressor YP_002997569.1 1803304 D 486410 CDS YP_002997570.1 251783265 8110472 complement(1804462..1804929) 1 NC_012891.1 Regulates rRNA biosynthesis by transcriptional antitermination; transcription antitermination protein NusB 1804929 nusB 8110472 nusB Streptococcus dysgalactiae subsp. equisimilis GGS_124 transcription antitermination protein NusB YP_002997570.1 1804462 R 486410 CDS YP_002997571.1 251783266 8111726 complement(1804904..1805293) 1 NC_012891.1 similar to general stress protein Gls24 family [Streptococcus pyogenes MGAS6180]; Gls24 family general stress protein 1805293 8111726 SDEG_1875 Streptococcus dysgalactiae subsp. equisimilis GGS_124 Gls24 family general stress protein YP_002997571.1 1804904 R 486410 CDS YP_002997572.1 251783267 8110664 complement(1805339..1805896) 1 NC_012891.1 Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA; elongation factor P 1805896 efp 8110664 efp Streptococcus dysgalactiae subsp. equisimilis GGS_124 elongation factor P YP_002997572.1 1805339 R 486410 CDS YP_002997573.1 251783268 8111866 complement(1805984..1806451) 1 NC_012891.1 similar to ComE operon protein 2 [Streptococcus pyogenes MGAS6180]; ComE operon protein 2 1806451 comEB 8111866 comEB Streptococcus dysgalactiae subsp. equisimilis GGS_124 ComE operon protein 2 YP_002997573.1 1805984 R 486410 CDS YP_002997574.1 251783269 8111633 complement(1806485..1807597) 1 NC_012891.1 similar to Xaa-Pro dipeptidase [Streptococcus pyogenes MGAS6180]; Xaa-Pro dipeptidase 1807597 8111633 SDEG_1878 Streptococcus dysgalactiae subsp. equisimilis GGS_124 Xaa-Pro dipeptidase YP_002997574.1 1806485 R 486410 CDS YP_002997575.1 251783270 8110665 complement(1807673..1810531) 1 NC_012891.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate; excinuclease ABC subunit A 1810531 uvrA 8110665 uvrA Streptococcus dysgalactiae subsp. equisimilis GGS_124 excinuclease ABC subunit A YP_002997575.1 1807673 R 486410 CDS YP_002997576.1 251783271 8111944 1810704..1811648 1 NC_012891.1 similar to magnesium and cobalt transport protein corA [Streptococcus pyogenes MGAS10394]; magnesium and cobalt transport protein corA 1811648 corA 8111944 corA Streptococcus dysgalactiae subsp. equisimilis GGS_124 magnesium and cobalt transport protein corA YP_002997576.1 1810704 D 486410 CDS YP_002997577.1 251783272 8111642 1811780..1812436 1 NC_012891.1 similar to hypothetical membrane spanning protein [Streptococcus pyogenes MGAS5005]; hypothetical protein 1812436 8111642 SDEG_1881 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002997577.1 1811780 D 486410 CDS YP_002997578.1 251783273 8110666 complement(1812567..1812806) 1 NC_012891.1 binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit; 30S ribosomal protein S18 1812806 rpsR 8110666 rpsR Streptococcus dysgalactiae subsp. equisimilis GGS_124 30S ribosomal protein S18 YP_002997578.1 1812567 R 486410 CDS YP_002997579.1 251783274 8111109 complement(1812971..1813462) 1 NC_012891.1 binds to single stranded DNA and may facilitate the binding and interaction of other proteins to DNA; single-stranded DNA-binding protein 1813462 ssb2 8111109 ssb2 Streptococcus dysgalactiae subsp. equisimilis GGS_124 single-stranded DNA-binding protein YP_002997579.1 1812971 R 486410 CDS YP_002997580.1 251783275 8110505 complement(1813484..1813774) 1 NC_012891.1 binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21; 30S ribosomal protein S6 1813774 rpsF 8110505 rpsF Streptococcus dysgalactiae subsp. equisimilis GGS_124 30S ribosomal protein S6 YP_002997580.1 1813484 R 486410 CDS YP_002997581.1 251783276 8111097 complement(1814733..1814969) 1 NC_012891.1 similar to hypothetical protein SpyM50294 [Streptococcus pyogenes str. Manfredo]; hypothetical protein 1814969 8111097 SDEG_1885 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002997581.1 1814733 R 486410 CDS YP_002997582.1 251783277 8110667 1815192..1816358 1 NC_012891.1 similar to A/G-specific adenine glycosylase [Streptococcus equi subsp. zooepidemicus MGCS10565]; A/G-specific adenine glycosylase 1816358 mutY 8110667 mutY Streptococcus dysgalactiae subsp. equisimilis GGS_124 A/G-specific adenine glycosylase YP_002997582.1 1815192 D 486410 CDS YP_002997583.1 251783278 8111698 complement(1816409..1816723) 1 NC_012891.1 similar to thioredoxin [Streptococcus equi subsp. zooepidemicus MGCS10565]; thioredoxin 1816723 trxA 8111698 trxA Streptococcus dysgalactiae subsp. equisimilis GGS_124 thioredoxin YP_002997583.1 1816409 R 486410 CDS YP_002997584.1 251783279 8111933 1816949..1818268 1 NC_012891.1 Involved in disulfide oxidoreductase activity and electron transport; pyridine nucleotide-disulfide oxidoreductase 1818268 ykgC 8111933 ykgC Streptococcus dysgalactiae subsp. equisimilis GGS_124 pyridine nucleotide-disulfide oxidoreductase YP_002997584.1 1816949 D 486410 CDS YP_002997585.1 251783280 8111966 complement(1818361..1820697) 1 NC_012891.1 similar to recombination inhibitory protein MutS2 [Streptococcus equi subsp. zooepidemicus MGCS10565]; recombination inhibitory protein MutS2 1820697 mutSB 8111966 mutSB Streptococcus dysgalactiae subsp. equisimilis GGS_124 recombination inhibitory protein MutS2 YP_002997585.1 1818361 R 486410 CDS YP_002997586.1 251783281 8111696 complement(1820853..1821398) 1 NC_012891.1 similar to colicin V production protein [Streptococcus pyogenes MGAS5005]; colicin V production protein 1821398 8111696 SDEG_1890 Streptococcus dysgalactiae subsp. equisimilis GGS_124 colicin V production protein YP_002997586.1 1820853 R 486410 CDS YP_002997587.1 251783282 8110668 complement(1821401..1821709) 1 NC_012891.1 similar to hypothetical protein SpyM50287 [Streptococcus pyogenes str. Manfredo]; hypothetical protein 1821709 8110668 SDEG_1891 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002997587.1 1821401 R 486410 CDS YP_002997588.1 251783283 8110669 1821866..1822765 1 NC_012891.1 An endonuclease that specifically degrades the RNA strand of RNA-DNA hybrids; ribonuclease HIII 1822765 8110669 SDEG_1892 Streptococcus dysgalactiae subsp. equisimilis GGS_124 ribonuclease HIII YP_002997588.1 1821866 D 486410 CDS YP_002997589.1 251783284 8110670 1822787..1823380 1 NC_012891.1 similar to signal peptidase I [Streptococcus pyogenes MGAS10394]; signal peptidase I 1823380 spi 8110670 spi Streptococcus dysgalactiae subsp. equisimilis GGS_124 signal peptidase I YP_002997589.1 1822787 D 486410 CDS YP_002997590.1 251783285 8110497 1823440..1825893 1 NC_012891.1 similar to exodeoxyribonuclease V alpha chain [Streptococcus pyogenes MGAS5005]; exodeoxyribonuclease V subunit alpha 1825893 recD 8110497 recD Streptococcus dysgalactiae subsp. equisimilis GGS_124 exodeoxyribonuclease V subunit alpha YP_002997590.1 1823440 D 486410 CDS YP_002997591.1 251783286 8111032 1825984..1826472 1 NC_012891.1 similar to hypothetical protein SPs0273 [Streptococcus pyogenes SSI-1]; hypothetical protein 1826472 8111032 SDEG_1895 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002997591.1 1825984 D 486410 CDS YP_002997592.1 251783287 8110671 complement(1826561..1827658) 1 NC_012891.1 involved in translesion DNA polymerization with beta clamp of polymerase III; belongs to Y family of polymerases; does not contain proofreading function; DNA polymerase IV 1827658 dinB 8110671 dinB Streptococcus dysgalactiae subsp. equisimilis GGS_124 DNA polymerase IV YP_002997592.1 1826561 R 486410 CDS YP_002997593.1 251783288 8111672 1827867..1830194 1 NC_012891.1 similar to formate acetyltransferase [Streptococcus pyogenes MGAS5005]; formate acetyltransferase 1830194 pfl 8111672 pfl Streptococcus dysgalactiae subsp. equisimilis GGS_124 formate acetyltransferase YP_002997593.1 1827867 D 486410 CDS YP_002997594.1 251783289 8111284 1830299..1830751 1 NC_012891.1 similar to acetyltransferase GNAT family [Streptococcus thermophilus LMD-9]; GNAT family acetyltransferase 1830751 8111284 SDEG_1898 Streptococcus dysgalactiae subsp. equisimilis GGS_124 GNAT family acetyltransferase YP_002997594.1 1830299 D 486410 CDS YP_002997595.1 251783290 8110672 complement(1830875..1832782) 1 NC_012891.1 similar to alpha amylase catalytic region [Chloroflexus aurantiacus J-10-fl]; alpha amylase 1832782 8110672 SDEG_1899 Streptococcus dysgalactiae subsp. equisimilis GGS_124 alpha amylase YP_002997595.1 1830875 R 486410 CDS YP_002997596.1 251783291 8110673 complement(1832869..1834440) 1 NC_012891.1 similar to ABC-type sugar transport system periplasmic component [Lactococcus lactis subsp. cremoris SK11]; sugar ABC transporter substrate-binding protein 1834440 8110673 SDEG_1900 Streptococcus dysgalactiae subsp. equisimilis GGS_124 sugar ABC transporter substrate-binding protein YP_002997596.1 1832869 R 486410 CDS YP_002997597.1 251783292 8110674 complement(1834507..1835160) 1 NC_012891.1 similar to hypothetical protein llmg 1837 [Lactococcus lactis subsp. cremoris MG1363]; hypothetical protein 1835160 8110674 SDEG_1901 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002997597.1 1834507 R 486410 CDS YP_002997598.1 251783293 8110675 complement(1835172..1836071) 1 NC_012891.1 similar to ABC-type sugar transport system permease component [Lactococcus lactis subsp. cremoris SK11]; sugar ABC transporter permease 1836071 8110675 SDEG_1902 Streptococcus dysgalactiae subsp. equisimilis GGS_124 sugar ABC transporter permease YP_002997598.1 1835172 R 486410 CDS YP_002997599.1 251783294 8110676 complement(1836084..1837022) 1 NC_012891.1 similar to ABC-type polysaccharide transport system permease component [Lactococcus lactis subsp. cremoris SK11]; polysaccharide ABC transporter permease 1837022 8110676 SDEG_1903 Streptococcus dysgalactiae subsp. equisimilis GGS_124 polysaccharide ABC transporter permease YP_002997599.1 1836084 R 486410 CDS YP_002997600.1 251783295 8110677 1837629..1838660 1 NC_012891.1 similar to regulatory protein LacI [Clostridium beijerinckii NCIMB 8052]; regulatory protein, LacI 1838660 8110677 SDEG_1904 Streptococcus dysgalactiae subsp. equisimilis GGS_124 regulatory protein, LacI YP_002997600.1 1837629 D 486410 CDS YP_002997601.1 251783296 8110678 complement(1838772..1839707) 1 NC_012891.1 similar to beta-lactamase family protein [Streptococcus pyogenes MGAS2096]; beta-lactamase 1839707 8110678 SDEG_1905 Streptococcus dysgalactiae subsp. equisimilis GGS_124 beta-lactamase YP_002997601.1 1838772 R 486410 CDS YP_002997602.1 251783297 8110679 complement(1839704..1840456) 1 NC_012891.1 similar to hypothetical cytosolic protein [Streptococcus pyogenes MGAS10750]; hypothetical protein 1840456 8110679 SDEG_1906 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002997602.1 1839704 R 486410 CDS YP_002997603.1 251783298 8110680 1840682..1841623 1 NC_012891.1 similar to hypothetical membrane spanning protein [Streptococcus pyogenes MGAS2096]; hypothetical protein 1841623 8110680 SDEG_1907 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002997603.1 1840682 D 486410 CDS YP_002997604.1 251783299 8110681 complement(1841727..1842575) 1 NC_012891.1 similar to hypothetical protein SSU98 0262 [Streptococcus suis 98HAH33]; hypothetical protein 1842575 8110681 SDEG_1908 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002997604.1 1841727 R 486410 CDS YP_002997605.1 251783300 8110682 1842702..1844984 1 NC_012891.1 catalyzes the removal of N-terminal dipeptides when proline is the penultimate residue; x-prolyl-dipeptidyl aminopeptidase 1844984 pepX 8110682 pepX Streptococcus dysgalactiae subsp. equisimilis GGS_124 x-prolyl-dipeptidyl aminopeptidase YP_002997605.1 1842702 D 486410 CDS YP_002997606.1 251783301 8111281 complement(1845057..1845449) 1 NC_012891.1 similar to hypothetical protein Sez 0318 [Streptococcus equi subsp. zooepidemicus MGCS10565]; hypothetical protein 1845449 8111281 SDEG_1910 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002997606.1 1845057 R 486410 CDS YP_002997607.1 251783302 8110683 complement(1845619..1845840) 1 NC_012891.1 similar to hypothetical protein spyM18 1923 [Streptococcus pyogenes MGAS8232]; hypothetical protein 1845840 8110683 SDEG_1911 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002997607.1 1845619 R 486410 CDS YP_002997608.1 251783303 8110684 1846010..1846384 1 NC_012891.1 similar to transcriptional regulator [Streptococcus pyogenes MGAS6180]; transcriptional regulator 1846384 8110684 SDEG_1912 Streptococcus dysgalactiae subsp. equisimilis GGS_124 transcriptional regulator YP_002997608.1 1846010 D 486410 CDS YP_002997609.1 251783304 8110685 1846577..1846876 1 NC_012891.1 similar to hypothetical cytosolic protein [Streptococcus pyogenes MGAS2096]; hypothetical protein 1846876 8110685 SDEG_1913 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002997609.1 1846577 D 486410 CDS YP_002997610.1 251783305 8110686 complement(1846933..1847670) 1 NC_012891.1 similar to transcriptional regulator MerR family [Streptococcus pyogenes MGAS5005]; MerR family transcriptional regulator 1847670 8110686 SDEG_1914 Streptococcus dysgalactiae subsp. equisimilis GGS_124 MerR family transcriptional regulator YP_002997610.1 1846933 R 486410 CDS YP_002997611.1 251783306 8110687 complement(1847823..1848422) 1 NC_012891.1 3'-5' exonuclease of DNA polymerase III; DNA polymerase III subunit epsilon 1848422 dnaQ 8110687 dnaQ Streptococcus dysgalactiae subsp. equisimilis GGS_124 DNA polymerase III subunit epsilon YP_002997611.1 1847823 R 486410 CDS YP_002997612.1 251783307 8111851 complement(1848458..1849009) 1 NC_012891.1 similar to DNA-binding protein [Streptococcus pyogenes str. Manfredo]; DNA-binding protein 1849009 8111851 SDEG_1916 Streptococcus dysgalactiae subsp. equisimilis GGS_124 DNA-binding protein YP_002997612.1 1848458 R 486410 CDS YP_002997613.1 251783308 8110688 1849363..1849596 1 NC_012891.1 similar to transposase [Streptococcus criceti]; transposase 1849596 paaB 8110688 paaB Streptococcus dysgalactiae subsp. equisimilis GGS_124 transposase YP_002997613.1 1849363 D 486410 CDS YP_002997614.1 251783309 8111747 1849647..1850822 1 NC_012891.1 similar to hypothetical protein SPs0257 [Streptococcus pyogenes SSI-1]; hypothetical protein 1850822 8111747 SDEG_1918 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002997614.1 1849647 D 486410 CDS YP_002997615.1 251783310 8110689 complement(1850882..1851136) 1 NC_012891.1 similar to hypothetical protein [Streptococcus thermophilus]; hypothetical protein 1851136 8110689 SDEG_1919 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002997615.1 1850882 R 486410 CDS YP_002997616.1 251783311 8110690 1851477..1851746 1 NC_012891.1 located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group do not appear to have the zinc-binding motif; 30S ribosomal protein S14 1851746 rpsN 8110690 rpsN Streptococcus dysgalactiae subsp. equisimilis GGS_124 30S ribosomal protein S14 YP_002997616.1 1851477 D 486410 CDS YP_002997617.1 251783312 8111106 complement(1852076..1853092) 1 NC_012891.1 in most organisms, only the N-terminal domain is present in a single polypeptide; in some archaea this domain is fused to a kinase domain; this gene is essential for growth in Escherichia coli and Bacillus subtilis; the secreted glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins; the Pyrococcus structure shows DNA-binding properties, iron-binding, ATP-binding, and AP endonuclease activity; DNA-binding/iron metalloprotein/AP endonuclease 1853092 8111106 SDEG_1921 Streptococcus dysgalactiae subsp. equisimilis GGS_124 DNA-binding/iron metalloprotein/AP endonuclease YP_002997617.1 1852076 R 486410 CDS YP_002997618.1 251783313 8112460 complement(1853082..1853537) 1 NC_012891.1 similar to ribosomal-protein-alanine acetyltransferase [Streptococcus pyogenes MGAS6180]; ribosomal-protein-alanine acetyltransferase 1853537 8112460 SDEG_1922 Streptococcus dysgalactiae subsp. equisimilis GGS_124 ribosomal-protein-alanine acetyltransferase YP_002997618.1 1853082 R 486410 CDS YP_002997619.1 251783314 8112461 complement(1853509..1854240) 1 NC_012891.1 similar to non-proteolytic protein peptidase family M22 [Streptococcus pyogenes MGAS10270]; non-proteolytic protein, peptidase family M22 1854240 8112461 SDEG_1923 Streptococcus dysgalactiae subsp. equisimilis GGS_124 non-proteolytic protein, peptidase family M22 YP_002997619.1 1853509 R 486410 CDS YP_002997620.1 251783315 8112462 1854493..1854723 1 NC_012891.1 similar to hypothetical protein SpyM50257 [Streptococcus pyogenes str. Manfredo]; hypothetical protein 1854723 8112462 SDEG_1924 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002997620.1 1854493 D 486410 CDS YP_002997621.1 251783316 8112463 1854725..1856407 1 NC_012891.1 similar to Zn-dependent hydrolase [Streptococcus pyogenes MGAS10394]; Zn-dependent hydrolase 1856407 8112463 SDEG_1925 Streptococcus dysgalactiae subsp. equisimilis GGS_124 Zn-dependent hydrolase YP_002997621.1 1854725 D 486410 CDS YP_002997622.1 251783317 8112464 complement(1856586..1857518) 1 NC_012891.1 similar to oligopeptide transport ATP-binding protein OppF [Streptococcus equi subsp. zooepidemicus MGCS10565]; oligopeptide transport ATP-binding protein 1857518 oppF 8112464 oppF Streptococcus dysgalactiae subsp. equisimilis GGS_124 oligopeptide transport ATP-binding protein YP_002997622.1 1856586 R 486410 CDS YP_002997623.1 251783318 8111742 complement(1857511..1858563) 1 NC_012891.1 similar to oligopeptide transport ATP-binding protein OppD [Streptococcus equi subsp. zooepidemicus MGCS10565]; oligopeptide transport ATP-binding protein 1858563 oppD 8111742 oppD Streptococcus dysgalactiae subsp. equisimilis GGS_124 oligopeptide transport ATP-binding protein YP_002997623.1 1857511 R 486410 CDS YP_002997624.1 251783319 8111740 complement(1858575..1859606) 1 NC_012891.1 similar to oligopeptide transport system permease protein OppC [Streptococcus equi subsp. zooepidemicus MGCS10565]; oligopeptide transport system permease 1859606 oppC 8111740 oppC Streptococcus dysgalactiae subsp. equisimilis GGS_124 oligopeptide transport system permease YP_002997624.1 1858575 R 486410 CDS YP_002997625.1 251783320 8111738 complement(1859616..1860530) 1 NC_012891.1 similar to oligopeptide transport system permease protein OppB [Streptococcus equi subsp. zooepidemicus MGCS10565]; oligopeptide transport system permease 1860530 oppB 8111738 oppB Streptococcus dysgalactiae subsp. equisimilis GGS_124 oligopeptide transport system permease YP_002997625.1 1859616 R 486410 CDS YP_002997626.1 251783321 8111736 complement(1860798..1862453) 1 NC_012891.1 similar to oligopeptide-binding protein OppA precursor [Streptococcus equi subsp. zooepidemicus MGCS10565]; oligopeptide-binding protein 1862453 oppA 8111736 oppA Streptococcus dysgalactiae subsp. equisimilis GGS_124 oligopeptide-binding protein YP_002997626.1 1860798 R 486410 CDS YP_002997627.1 251783322 8111734 complement(1862686..1864032) 1 NC_012891.1 similar to glutamine synthetase [Streptococcus pyogenes str. Manfredo]; glutamine synthetase 1864032 glnA 8111734 glnA Streptococcus dysgalactiae subsp. equisimilis GGS_124 glutamine synthetase YP_002997627.1 1862686 R 486410 CDS YP_002997628.1 251783323 8112002 complement(1864070..1864441) 1 NC_012891.1 similar to transcriptional regulator MerR family [Streptococcus pyogenes MGAS10394]; MerR family transcriptional regulator 1864441 8112002 SDEG_1932 Streptococcus dysgalactiae subsp. equisimilis GGS_124 MerR family transcriptional regulator YP_002997628.1 1864070 R 486410 CDS YP_002997629.1 251783324 8112465 complement(1864518..1865039) 1 NC_012891.1 similar to hypothetical protein SpyM50253 [Streptococcus pyogenes str. Manfredo]; hypothetical protein 1865039 8112465 SDEG_1933 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002997629.1 1864518 R 486410 CDS YP_002997630.1 251783325 8112466 complement(1865536..1866732) 1 NC_012891.1 Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway; phosphoglycerate kinase 1866732 pgk 8112466 pgk Streptococcus dysgalactiae subsp. equisimilis GGS_124 phosphoglycerate kinase YP_002997630.1 1865536 R 486410 CDS YP_002997631.1 251783326 8111286 complement(1866916..1867773) 1 NC_012891.1 similar to acid phosphatase [Streptococcus dysgalactiae subsp. equisimilis]; acid phosphatase 1867773 lppC 8111286 lppC Streptococcus dysgalactiae subsp. equisimilis GGS_124 acid phosphatase YP_002997631.1 1866916 R 486410 CDS YP_002997632.1 251783327 8110908 complement(1867957..1868967) 1 NC_012891.1 similar to glyceraldehyde-3-phosphate dehydrogenaseplasmin receptor [Streptococcus pyogenes str. Manfredo]; glyceraldehyde-3-phosphate dehydrogenase 1868967 gapA 8110908 gapA Streptococcus dysgalactiae subsp. equisimilis GGS_124 glyceraldehyde-3-phosphate dehydrogenase YP_002997632.1 1867957 R 486410 CDS YP_002997633.1 251783328 8111984 complement(1869307..1871385) 1 NC_012891.1 EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene; elongation factor G 1871385 fus 8111984 fus Streptococcus dysgalactiae subsp. equisimilis GGS_124 elongation factor G YP_002997633.1 1869307 R 486410 CDS YP_002997634.1 251783329 8111981 complement(1871803..1872273) 1 NC_012891.1 binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit; 30S ribosomal protein S7 1872273 rpsG 8111981 rpsG Streptococcus dysgalactiae subsp. equisimilis GGS_124 30S ribosomal protein S7 YP_002997634.1 1871803 R 486410 CDS YP_002997635.1 251783330 8111098 complement(1872294..1872707) 1 NC_012891.1 interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance; 30S ribosomal protein S12 1872707 rpsL 8111098 rpsL Streptococcus dysgalactiae subsp. equisimilis GGS_124 30S ribosomal protein S12 YP_002997635.1 1872294 R 486410 CDS YP_002997636.1 251783331 8111103 complement(1872968..1875589) 1 NC_012891.1 similar to surface exclusion protein [Streptococcus pyogenes MGAS10750]; surface exclusion protein 1875589 prgA 8111103 prgA Streptococcus dysgalactiae subsp. equisimilis GGS_124 surface exclusion protein YP_002997636.1 1872968 R 486410 CDS YP_002997637.1 251783332 8111308 complement(1875580..1876419) 1 NC_012891.1 similar to purine operon repressor [Streptococcus pyogenes MGAS10394]; pur operon repressor 1876419 purR 8111308 purR Streptococcus dysgalactiae subsp. equisimilis GGS_124 pur operon repressor YP_002997637.1 1875580 R 486410 CDS YP_002997638.1 251783333 8111336 complement(1876519..1877457) 1 NC_012891.1 similar to CMP-binding factor [Streptococcus pyogenes MGAS5005]; CMP-binding factor 1877457 cbf 8111336 cbf Streptococcus dysgalactiae subsp. equisimilis GGS_124 CMP-binding factor YP_002997638.1 1876519 R 486410 CDS YP_002997639.1 251783334 8111604 complement(1877447..1878718) 1 NC_012891.1 similar to RmuC family protein [Streptococcus pyogenes MGAS10394]; RmuC family DNA recombination protein 1878718 8111604 SDEG_1943 Streptococcus dysgalactiae subsp. equisimilis GGS_124 RmuC family DNA recombination protein YP_002997639.1 1877447 R 486410 CDS YP_002997640.1 251783335 8112467 complement(1878720..1879352) 1 NC_012891.1 similar to thiamine pyrophosphokinase [Streptococcus pyogenes MGAS5005]; thiamine pyrophosphokinase 1879352 8112467 SDEG_1944 Streptococcus dysgalactiae subsp. equisimilis GGS_124 thiamine pyrophosphokinase YP_002997640.1 1878720 R 486410 CDS YP_002997641.1 251783336 8112468 complement(1879345..1880007) 1 NC_012891.1 catalyzes the interconversion of D-ribulose 5-phosphate to xylulose 5-phosphate; ribulose-phosphate 3-epimerase 1880007 rpe 8112468 rpe Streptococcus dysgalactiae subsp. equisimilis GGS_124 ribulose-phosphate 3-epimerase YP_002997641.1 1879345 R 486410 CDS YP_002997642.1 251783337 8111056 complement(1880017..1880889) 1 NC_012891.1 EngC; RsgA; CpgA; circularly permuted GTPase; ribosome small subunit-dependent GTPase A; has the pattern G4-G1-G3 as opposed to other GTPases; interacts strongly with 30S ribosome which stimulates GTPase activity; ribosome-associated GTPase 1880889 8111056 SDEG_1946 Streptococcus dysgalactiae subsp. equisimilis GGS_124 ribosome-associated GTPase YP_002997642.1 1880017 R 486410 CDS YP_002997643.1 251783338 8112469 complement(1881312..1882208) 1 NC_012891.1 catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin; dimethyladenosine transferase 1882208 ksgA 8112469 ksgA Streptococcus dysgalactiae subsp. equisimilis GGS_124 dimethyladenosine transferase YP_002997643.1 1881312 R 486410 CDS YP_002997644.1 251783339 8110877 complement(1882298..1882909) 1 NC_012891.1 similar to ribonuclease M5 [Streptococcus pyogenes MGAS6180]; ribonuclease M5 1882909 8110877 SDEG_1948 Streptococcus dysgalactiae subsp. equisimilis GGS_124 ribonuclease M5 YP_002997644.1 1882298 R 486410 CDS YP_002997645.1 251783340 8112470 complement(1882860..1883651) 1 NC_012891.1 similar to TatD related DNase [Streptococcus pyogenes str. Manfredo]; TatD related DNase 1883651 tatD 8112470 tatD Streptococcus dysgalactiae subsp. equisimilis GGS_124 TatD related DNase YP_002997645.1 1882860 R 486410 CDS YP_002997646.1 251783341 8110513 1883793..1884269 1 NC_012891.1 similar to hydrolase [Staphylococcus aureus RF122]; hydrolase 1884269 8110513 SDEG_1950 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hydrolase YP_002997646.1 1883793 D 486410 CDS YP_002997647.1 251783342 8112471 1884393..1885223 1 NC_012891.1 similar to transcriptional regulator RpiR family [Streptococcus pyogenes MGAS5005]; RpiR family transcriptional regulator 1885223 8112471 SDEG_1951 Streptococcus dysgalactiae subsp. equisimilis GGS_124 RpiR family transcriptional regulator YP_002997647.1 1884393 D 486410 CDS YP_002997648.1 251783343 8112472 complement(1885339..1886226) 1 NC_012891.1 similar to N-acetylmannosamine kinase [Streptococcus pyogenes MGAS10394]; N-acetylmannosamine kinase 1886226 8112472 SDEG_1952 Streptococcus dysgalactiae subsp. equisimilis GGS_124 N-acetylmannosamine kinase YP_002997648.1 1885339 R 486410 CDS YP_002997649.1 251783344 8112473 complement(1886243..1887160) 1 NC_012891.1 similar to N-acetylneuraminate lyase [Streptococcus pyogenes MGAS5005]; N-acetylneuraminate lyase 1887160 nanH 8112473 nanH Streptococcus dysgalactiae subsp. equisimilis GGS_124 N-acetylneuraminate lyase YP_002997649.1 1886243 R 486410 CDS YP_002997650.1 251783345 8111708 complement(1887172..1887834) 1 NC_012891.1 similar to hypothetical membrane spanning protein [Streptococcus pyogenes MGAS5005]; hypothetical protein 1887834 8111708 SDEG_1954 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002997650.1 1887172 R 486410 CDS YP_002997651.1 251783346 8112474 complement(1887878..1888333) 1 NC_012891.1 similar to hypothetical protein spyM18 0238 [Streptococcus pyogenes MGAS8232]; hypothetical protein 1888333 8112474 SDEG_1955 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002997651.1 1887878 R 486410 CDS YP_002997652.1 251783347 8112475 complement(1888353..1889183) 1 NC_012891.1 similar to N-acetylneuraminate transport system permease protein [Streptococcus pyogenes MGAS6180]; N-acetylneuraminate transport system permease 1889183 8112475 SDEG_1956 Streptococcus dysgalactiae subsp. equisimilis GGS_124 N-acetylneuraminate transport system permease YP_002997652.1 1888353 R 486410 CDS YP_002997653.1 251783348 8112476 complement(1889196..1890185) 1 NC_012891.1 similar to N-acetylneuraminate transport system permease protein [Streptococcus pyogenes MGAS6180]; N-acetylneuraminate transport system permease 1890185 8112476 SDEG_1957 Streptococcus dysgalactiae subsp. equisimilis GGS_124 N-acetylneuraminate transport system permease YP_002997653.1 1889196 R 486410 CDS YP_002997654.1 251783349 8112477 complement(1890186..1891505) 1 NC_012891.1 similar to N-acetylneuraminate-binding protein [Streptococcus pyogenes MGAS5005]; N-acetylneuraminate-binding protein 1891505 8112477 SDEG_1958 Streptococcus dysgalactiae subsp. equisimilis GGS_124 N-acetylneuraminate-binding protein YP_002997654.1 1890186 R 486410 CDS YP_002997655.1 251783350 8112478 complement(1891554..1892258) 1 NC_012891.1 Converts N-acetylmannosamine-6-phosphate to N-acetylglucosamine-6-phosphate; N-acetylmannosamine-6-phosphate 2-epimerase 1892258 8112478 SDEG_1959 Streptococcus dysgalactiae subsp. equisimilis GGS_124 N-acetylmannosamine-6-phosphate 2-epimerase YP_002997655.1 1891554 R 486410 CDS YP_002997656.1 251783351 8112479 complement(1892589..1892723) 1 NC_012891.1 in Escherichia coli transcription of this gene is enhanced by polyamines; 50S ribosomal protein L34 1892723 rpmH 8112479 rpmH Streptococcus dysgalactiae subsp. equisimilis GGS_124 50S ribosomal protein L34 YP_002997656.1 1892589 R 486410 CDS YP_002997657.1 251783352 8111086 complement(1893036..1893950) 1 NC_012891.1 similar to jag protein [Streptococcus pyogenes MGAS5005]; jag protein 1893950 8111086 SDEG_1961 Streptococcus dysgalactiae subsp. equisimilis GGS_124 jag protein YP_002997657.1 1893036 R 486410 CDS YP_002997658.1 251783353 8112480 complement(1893962..1894777) 1 NC_012891.1 similar to membrane protein oxaA 1 precursor [Streptococcus pyogenes NZ131]; membrane protein OxaA 1894777 8112480 SDEG_1962 Streptococcus dysgalactiae subsp. equisimilis GGS_124 membrane protein OxaA YP_002997658.1 1893962 R 486410 CDS YP_002997659.1 251783354 8112481 complement(1894755..1895114) 1 NC_012891.1 protein component of RNaseP which catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'terminus; this enzyme also cleaves other RNA substrates; ribonuclease P 1895114 rnpA 8112481 rnpA Streptococcus dysgalactiae subsp. equisimilis GGS_124 ribonuclease P YP_002997659.1 1894755 R 486410 CDS YP_002997660.1 251783355 8111052 complement(1895656..1896396) 1 NC_012891.1 similar to response regulator FasA [Streptococcus dysgalactiae subsp. equisimilis]; response regulator 1896396 fasA 8111052 fasA Streptococcus dysgalactiae subsp. equisimilis GGS_124 response regulator YP_002997660.1 1895656 R 486410 CDS YP_002997661.1 251783356 8111882 complement(1896400..1897683) 1 NC_012891.1 similar to sensory transduction protein kinase [Streptococcus pyogenes MGAS6180]; sensory transduction protein kinase 1897683 fasC 8111882 fasC Streptococcus dysgalactiae subsp. equisimilis GGS_124 sensory transduction protein kinase YP_002997661.1 1896400 R 486410 CDS YP_002997662.1 251783357 8111884 complement(1897684..1899027) 1 NC_012891.1 similar to FasB [Streptococcus pyogenes MGAS10394]; sensory transduction protein kinase 1899027 fasB 8111884 fasB Streptococcus dysgalactiae subsp. equisimilis GGS_124 sensory transduction protein kinase YP_002997662.1 1897684 R 486410 CDS YP_002997663.1 251783358 8111883 complement(1899642..1901090) 1 NC_012891.1 Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation; glutamyl-tRNA synthetase 1901090 gltX 8111883 gltX Streptococcus dysgalactiae subsp. equisimilis GGS_124 glutamyl-tRNA synthetase YP_002997663.1 1899642 R 486410 CDS YP_002997664.1 251783359 8112011 complement(1901223..1902491) 1 NC_012891.1 similar to lantibiotic efflux protein [Streptococcus suis 05ZYH33]; lantibiotic efflux protein 1902491 8112011 SDEG_1968 Streptococcus dysgalactiae subsp. equisimilis GGS_124 lantibiotic efflux protein YP_002997664.1 1901223 R 486410 CDS YP_002997665.1 251783360 8112482 complement(1902586..1903287) 1 NC_012891.1 similar to hypothetical protein SSA 1981 [Streptococcus sanguinis SK36]; hypothetical protein 1903287 8112482 SDEG_1969 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002997665.1 1902586 R 486410 CDS YP_002997666.1 251783361 8112483 complement(1903291..1903737) 1 NC_012891.1 similar to response regulator of the LytR/AlgR family [Streptococcus suis 98HAH33]; LytR/AlgR family response regulator 1903737 8112483 SDEG_1970 Streptococcus dysgalactiae subsp. equisimilis GGS_124 LytR/AlgR family response regulator YP_002997666.1 1903291 R 486410 CDS YP_002997667.1 251783362 8112484 complement(1903966..1904682) 1 NC_012891.1 similar to HTH DNA-binding protein [Streptococcus equi subsp. zooepidemicus MGCS10565]; HTH DNA-binding protein 1904682 8112484 SDEG_1971 Streptococcus dysgalactiae subsp. equisimilis GGS_124 HTH DNA-binding protein YP_002997667.1 1903966 R 486410 CDS YP_002997668.1 251783363 8112485 complement(1904818..1905312) 1 NC_012891.1 similar to carbonic anhydrase [Streptococcus pyogenes MGAS10394]; carbonic anhydrase 1905312 8112485 SDEG_1972 Streptococcus dysgalactiae subsp. equisimilis GGS_124 carbonic anhydrase YP_002997668.1 1904818 R 486410 CDS YP_002997669.1 251783364 8112486 complement(1905502..1906764) 1 NC_012891.1 similar to DNA repair protein [Streptococcus pyogenes str. Manfredo]; DNA repair protein 1906764 radA 8112486 radA Streptococcus dysgalactiae subsp. equisimilis GGS_124 DNA repair protein YP_002997669.1 1905502 R 486410 CDS YP_002997670.1 251783365 8111348 complement(1906946..1907392) 1 NC_012891.1 catalyzes the formation of dUMP from dUTP; deoxyuridine 5'-triphosphate nucleotidohydrolase 1907392 dut 8111348 dut Streptococcus dysgalactiae subsp. equisimilis GGS_124 deoxyuridine 5'-triphosphate nucleotidohydrolase YP_002997670.1 1906946 R 486410 CDS YP_002997671.1 251783366 8111861 complement(1907500..1908267) 1 NC_012891.1 similar to hypothetical cytosolic protein [Streptococcus pyogenes MGAS6180]; hypothetical protein 1908267 8111861 SDEG_1975 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002997671.1 1907500 R 486410 CDS YP_002997672.1 251783367 8112487 complement(1908386..1910170) 1 NC_012891.1 similar to multidrug resistance ABC transporter ATP-binding and permease protein [Streptococcus pyogenes MGAS10394]; multidrug resistance ABC transporter ATP-bindingprotein/permease 1910170 8112487 SDEG_1976 Streptococcus dysgalactiae subsp. equisimilis GGS_124 multidrug resistance ABC transporter ATP-bindingprotein/permease YP_002997672.1 1908386 R 486410 CDS YP_002997673.1 251783368 8112488 complement(1910170..1911879) 1 NC_012891.1 similar to ABC transporter ATP-binding protein [Streptococcus pyogenes M1 GAS]; ABC transporter ATP-binding protein 1911879 8112488 SDEG_1977 Streptococcus dysgalactiae subsp. equisimilis GGS_124 ABC transporter ATP-binding protein YP_002997673.1 1910170 R 486410 CDS YP_002997674.1 251783369 8112489 complement(1911872..1912321) 1 NC_012891.1 similar to hypothetical protein spyM18 0213 [Streptococcus pyogenes MGAS8232]; hypothetical protein 1912321 8112489 SDEG_1978 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002997674.1 1911872 R 486410 CDS YP_002997675.1 251783370 8112490 1912522..1913538 1 NC_012891.1 catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate; NAD(P)H-dependent glycerol-3-phosphate dehydrogenase 1913538 gpsA 8112490 gpsA Streptococcus dysgalactiae subsp. equisimilis GGS_124 NAD(P)H-dependent glycerol-3-phosphate dehydrogenase YP_002997675.1 1912522 D 486410 CDS YP_002997676.1 251783371 8112017 1913570..1914472 1 NC_012891.1 similar to UDP-glucose pyrophosphorylase [Streptococcus pyogenes MGAS8232]; UDP-glucose pyrophosphorylase 1914472 hasC 8112017 hasC Streptococcus dysgalactiae subsp. equisimilis GGS_124 UDP-glucose pyrophosphorylase YP_002997676.1 1913570 D 486410 CDS YP_002997677.1 251783372 8112027 1914653..1915279 1 NC_012891.1 similar to integral membrane protein [Lactobacillus plantarum WCFS1]; integral membrane protein 1915279 8112027 SDEG_1981 Streptococcus dysgalactiae subsp. equisimilis GGS_124 integral membrane protein YP_002997677.1 1914653 D 486410 CDS YP_002997678.1 251783373 8112491 complement(1915456..1916130) 1 NC_012891.1 similar to integral membrane protein (rhomboid family) [Streptococcus pyogenes MGAS10394]; integral membrane protein 1916130 8112491 SDEG_1982 Streptococcus dysgalactiae subsp. equisimilis GGS_124 integral membrane protein YP_002997678.1 1915456 R 486410 CDS YP_002997679.1 251783374 8112492 complement(1916127..1916654) 1 NC_012891.1 similar to 5-formyltetrahydrofolate cyclo-ligase family protein [Streptococcus agalactiae 2603V/R]; 5-formyltetrahydrofolate cyclo-ligase 1916654 8112492 SDEG_1983 Streptococcus dysgalactiae subsp. equisimilis GGS_124 5-formyltetrahydrofolate cyclo-ligase YP_002997679.1 1916127 R 486410 CDS YP_002997680.1 251783375 8112493 complement(1917195..1918778) 1 NC_012891.1 similar to fibronectin-binding protein [Streptococcus equi subsp. zooepidemicus]; fibronectin-binding protein 1918778 fnz 8112493 fnz Streptococcus dysgalactiae subsp. equisimilis GGS_124 fibronectin-binding protein YP_002997680.1 1917195 R 486410 CDS YP_002997681.1 251783376 8111901 1919210..1920715 1 NC_012891.1 similar to transcriptional regulator [Streptococcus pyogenes MGAS10270]; transcriptional regulator 1920715 rofA 8111901 rofA Streptococcus dysgalactiae subsp. equisimilis GGS_124 transcriptional regulator YP_002997681.1 1919210 D 486410 CDS YP_002997682.1 251783377 8111054 complement(1920829..1921953) 1 NC_012891.1 similar to hypothetical protein llmg 0526 [Lactococcus lactis subsp. cremoris MG1363]; hypothetical protein 1921953 8111054 SDEG_1986 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002997682.1 1920829 R 486410 CDS YP_002997683.1 251783378 8112494 complement(1921989..1922486) 1 NC_012891.1 similar to hypothetical protein BIFDEN 02311 [Bifidobacterium dentium ATCC 27678]; hypothetical protein 1922486 8112494 SDEG_1987 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002997683.1 1921989 R 486410 CDS YP_002997684.1 251783379 8112495 complement(1922748..1924097) 1 NC_012891.1 functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis; catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate; member of PGI family; glucose-6-phosphate isomerase 1924097 pgi 8112495 pgi Streptococcus dysgalactiae subsp. equisimilis GGS_124 glucose-6-phosphate isomerase YP_002997684.1 1922748 R 486410 CDS YP_002997685.1 251783380 8111285 complement(1924337..1924948) 1 NC_012891.1 similar to hypothetical protein; hypothetical protein [Streptococcus dysgalactiae subsp. equisimilis]; hypothetical protein 1924948 8111285 SDEG_1989 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002997685.1 1924337 R 486410 CDS YP_002997686.1 251783381 8112496 complement(1925033..1925653) 1 NC_012891.1 similar to hypothetical protein [Streptococcus dysgalactiae subsp. equisimilis]; hypothetical protein 1925653 8112496 SDEG_1990 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002997686.1 1925033 R 486410 CDS YP_002997687.1 251783382 8112497 complement(1925738..1926442) 1 NC_012891.1 similar to exotoxin G variant 4 [Streptococcus dysgalactiae subsp. equisimilis]; exotoxin G variant 4 1926442 spegg4 8112497 spegg4 Streptococcus dysgalactiae subsp. equisimilis GGS_124 exotoxin G variant 4 YP_002997687.1 1925738 R 486410 CDS YP_002997688.1 251783383 8110495 1926861..1927301 1 NC_012891.1 similar to hypothetical protein [Streptococcus dysgalactiae subsp. equisimilis]; hypothetical protein 1927301 8110495 SDEG_1992 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002997688.1 1926861 D 486410 CDS YP_002997689.1 251783384 8112498 1927307..1928086 1 NC_012891.1 similar to peptidoglycan endo-beta-N-acetylglucosaminidase [Streptococcus pyogenes MGAS10394]; peptidoglycan endo-beta-N-acetylglucosaminidase 1928086 8112498 SDEG_1993 Streptococcus dysgalactiae subsp. equisimilis GGS_124 peptidoglycan endo-beta-N-acetylglucosaminidase YP_002997689.1 1927307 D 486410 CDS YP_002997690.1 251783385 8112499 complement(1928188..1928715) 1 NC_012891.1 similar to tRNA-specific adenosine deaminase [Streptococcus pyogenes MGAS10394]; tRNA-specific adenosine deaminase 1928715 8112499 SDEG_1994 Streptococcus dysgalactiae subsp. equisimilis GGS_124 tRNA-specific adenosine deaminase YP_002997690.1 1928188 R 486410 CDS YP_002997691.1 251783386 8112500 complement(1928715..1929494) 1 NC_012891.1 similar to metal-dependent hydrolase [Streptococcus pyogenes MGAS10394]; metal-dependent hydrolase 1929494 8112500 SDEG_1995 Streptococcus dysgalactiae subsp. equisimilis GGS_124 metal-dependent hydrolase YP_002997691.1 1928715 R 486410 CDS YP_002997692.1 251783387 8112501 complement(1929634..1930173) 1 NC_012891.1 similar to BioY protein [Streptococcus pyogenes MGAS10750]; biotin transporter 1930173 bioY 8112501 bioY Streptococcus dysgalactiae subsp. equisimilis GGS_124 biotin transporter YP_002997692.1 1929634 R 486410 CDS YP_002997693.1 251783388 8112376 complement(1930177..1930488) 1 NC_012891.1 similar to zinc finger protein [Streptococcus pyogenes MGAS6180]; hypothetical protein 1930488 8112376 SDEG_1997 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002997693.1 1930177 R 486410 CDS YP_002997694.1 251783389 8112502 complement(1930693..1931835) 1 NC_012891.1 Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr); queuine tRNA-ribosyltransferase 1931835 tgt 8112502 tgt Streptococcus dysgalactiae subsp. equisimilis GGS_124 queuine tRNA-ribosyltransferase YP_002997694.1 1930693 R 486410 CDS YP_002997695.1 251783390 8110516 1932055..1932921 1 NC_012891.1 similar to integral membrane protein [Streptococcus pyogenes MGAS6180]; integral membrane protein 1932921 8110516 SDEG_1999 Streptococcus dysgalactiae subsp. equisimilis GGS_124 integral membrane protein YP_002997695.1 1932055 D 486410 CDS YP_002997696.1 251783391 8112503 complement(1933042..1933509) 1 NC_012891.1 similar to ferric uptake regulation protein [Streptococcus pyogenes MGAS5005]; ferric uptake regulation protein 1933509 perR 8112503 perR Streptococcus dysgalactiae subsp. equisimilis GGS_124 ferric uptake regulation protein YP_002997696.1 1933042 R 486410 CDS YP_002997697.1 251783392 8111282 complement(1933576..1934016) 1 NC_012891.1 similar to CoA binding protein [Streptococcus pyogenes MGAS10270]; CoA binding protein 1934016 8111282 SDEG_2001 Streptococcus dysgalactiae subsp. equisimilis GGS_124 CoA binding protein YP_002997697.1 1933576 R 486410 CDS YP_002997698.1 251783393 8112504 complement(1934223..1936865) 1 NC_012891.1 has 3'-5' exonuclease, 5'-3' exonuclease and 5'-3'polymerase activities, primarily functions to fill gaps during DNA replication and repair; DNA polymerase I 1936865 8112504 SDEG_2002 Streptococcus dysgalactiae subsp. equisimilis GGS_124 DNA polymerase I YP_002997698.1 1934223 R 486410 CDS YP_002997699.1 251783394 8112505 complement(1937013..1938740) 1 NC_012891.1 similar to glycine betaine-binding protein / glycine betaine transport system permease protein [Streptococcus pyogenes MGAS10750]; glycine betaine-binding protein/glycinebetaine transport system permease 1938740 opuABC 8112505 opuABC Streptococcus dysgalactiae subsp. equisimilis GGS_124 glycine betaine-binding protein/glycinebetaine transport system permease YP_002997699.1 1937013 R 486410 CDS YP_002997700.1 251783395 8111744 complement(1938758..1939954) 1 NC_012891.1 similar to glycine betaine transport ATP-binding protein [Streptococcus pyogenes str. Manfredo]; glycine betaine transport ATP-binding protein 1939954 opuAA 8111744 opuAA Streptococcus dysgalactiae subsp. equisimilis GGS_124 glycine betaine transport ATP-binding protein YP_002997700.1 1938758 R 486410 CDS YP_002997701.1 251783396 8111743 complement(1940386..1941330) 1 NC_012891.1 similar to diacylglycerol kinase catalytic subunit [Enterococcus faecalis; transcriptional regulator 1941330 8111743 SDEG_2005 Streptococcus dysgalactiae subsp. equisimilis GGS_124 transcriptional regulator YP_002997701.1 1940386 R 486410 CDS YP_002997702.1 251783397 8112506 complement(1941510..1942601) 1 NC_012891.1 similar to metal-dependent hydrolase [Streptococcus pyogenes MGAS10394]; L-ascorbate 6-phosphate lactonase 1942601 8112506 SDEG_2006 Streptococcus dysgalactiae subsp. equisimilis GGS_124 L-ascorbate 6-phosphate lactonase YP_002997702.1 1941510 R 486410 CDS YP_002997703.1 251783398 8112507 complement(1942898..1944544) 1 NC_012891.1 similar to transcription antiterminator BglG family [Streptococcus pyogenes MGAS10394]; BglG family transcription antiterminator 1944544 8112507 SDEG_2007 Streptococcus dysgalactiae subsp. equisimilis GGS_124 BglG family transcription antiterminator YP_002997703.1 1942898 R 486410 CDS YP_002997704.1 251783399 8112508 complement(1944827..1945543) 1 NC_012891.1 catalyzes the formation of D-xylulose 5-phosphate from L-ribulose 5-phosphate in the L-arabinose and L-ascorbate degradation pathways; L-ribulose-5-phosphate 4-epimerase 1945543 araD 8112508 araD Streptococcus dysgalactiae subsp. equisimilis GGS_124 L-ribulose-5-phosphate 4-epimerase YP_002997704.1 1944827 R 486410 CDS YP_002997705.1 251783400 8112330 complement(1945545..1946408) 1 NC_012891.1 L-xylulose 5-phosphate 3-epimerase activity not yet demonstrated; may be involved in the utilization of 2,3-diketo-L-gulonate; L-xylulose 5-phosphate 3-epimerase 1946408 8112330 SDEG_2009 Streptococcus dysgalactiae subsp. equisimilis GGS_124 L-xylulose 5-phosphate 3-epimerase YP_002997705.1 1945545 R 486410 CDS YP_002997706.1 251783401 8112509 complement(1946412..1947074) 1 NC_012891.1 catalyzes the formation of L-xylulose-5-phosphate from 3-keto-L-gulonate-6-phosphate in anaerobic L-ascorbate utilization; 3-keto-L-gulonate-6-phosphate decarboxylase 1947074 ulaD 8112509 ulaD Streptococcus dysgalactiae subsp. equisimilis GGS_124 3-keto-L-gulonate-6-phosphate decarboxylase YP_002997706.1 1946412 R 486410 CDS YP_002997707.1 251783402 8111941 complement(1947183..1947674) 1 NC_012891.1 similar to PTS system 3-keto-L-gulonate specific IIA component [Streptococcus pyogenes MGAS10750]; PTS system 3-keto-L-gulonate specific transporter subunit IIA 1947674 8111941 SDEG_2011 Streptococcus dysgalactiae subsp. equisimilis GGS_124 PTS system 3-keto-L-gulonate specific transporter subunit IIA YP_002997707.1 1947183 R 486410 CDS YP_002997708.1 251783403 8112510 complement(1947795..1948073) 1 NC_012891.1 similar to PTS system 3-keto-L-gulonate specific IIB component [Streptococcus pyogenes MGAS10394]; PTS system 3-keto-L-gulonate specific transporter subunit IIB 1948073 8112510 SDEG_2012 Streptococcus dysgalactiae subsp. equisimilis GGS_124 PTS system 3-keto-L-gulonate specific transporter subunit IIB YP_002997708.1 1947795 R 486410 CDS YP_002997709.1 251783404 8112511 complement(1948144..1949577) 1 NC_012891.1 membrane component; functions with enzymes IIB (sgaB; ulaB) and IIA (sgaA; ulaC) enzyme I and HPr for anaerobic utilization and uptake of L-ascorbate; sgaTBA are regulated by yifQ as well as Crp and Fnr; PTS system ascorbate-specific transporter subunit IIC 1949577 ulaA 8112511 ulaA Streptococcus dysgalactiae subsp. equisimilis GGS_124 PTS system ascorbate-specific transporter subunit IIC YP_002997709.1 1948144 R 486410 CDS YP_002997710.1 251783405 8111940 complement(1949882..1952383) 1 NC_012891.1 leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase; leucyl-tRNA synthetase 1952383 leuS 8111940 leuS Streptococcus dysgalactiae subsp. equisimilis GGS_124 leucyl-tRNA synthetase YP_002997710.1 1949882 R 486410 CDS YP_002997711.1 251783406 8112512 complement(1953272..1953436) 1 NC_012891.1 similar to hypothetical protein MGAS2096 Spy1064 [Streptococcus pyogenes MGAS2096]; hypothetical protein 1953436 8112512 SDEG_2016 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002997711.1 1953272 R 486410 CDS YP_002997712.1 251783407 8112513 1953454..1953957 1 NC_012891.1 similar to transposase [Streptococcus pyogenes MGAS10750]; transposase 1953957 8112513 SDEG_2017 Streptococcus dysgalactiae subsp. equisimilis GGS_124 transposase YP_002997712.1 1953454 D 486410 CDS YP_002997713.1 251783408 8112514 1953965..1954411 1 NC_012891.1 similar to transposase [Streptococcus pyogenes MGAS10394]; transposase 1954411 8112514 SDEG_2018 Streptococcus dysgalactiae subsp. equisimilis GGS_124 transposase YP_002997713.1 1953965 D 486410 CDS YP_002997714.1 251783409 8112515 1954464..1954754 1 NC_012891.1 similar to ISSag4 transposase orfA [Streptococcus agalactiae A909]; ISSag4, transposase orfA 1954754 8112515 SDEG_2019 Streptococcus dysgalactiae subsp. equisimilis GGS_124 ISSag4, transposase orfA YP_002997714.1 1954464 D 486410 CDS YP_002997715.1 251783410 8112516 1954790..1955230 1 NC_012891.1 similar to ISSdy1 transposase OrfB [Streptococcus agalactiae 2603V/R]; ISSdy1, transposase OrfB 1955230 8112516 SDEG_2020 Streptococcus dysgalactiae subsp. equisimilis GGS_124 ISSdy1, transposase OrfB YP_002997715.1 1954790 D 486410 CDS YP_002997716.1 251783411 8112517 1955157..1955501 1 NC_012891.1 similar to ISSdy1 transposase OrfB [Streptococcus agalactiae 2603V/R]; ISSdy1, transposase OrfB 1955501 8112517 SDEG_2021 Streptococcus dysgalactiae subsp. equisimilis GGS_124 ISSdy1, transposase OrfB YP_002997716.1 1955157 D 486410 CDS YP_002997717.1 251783412 8112518 complement(1955580..1955897) 1 NC_012891.1 no hit; hypothetical protein 1955897 8112518 SDEG_2022 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002997717.1 1955580 R 486410 CDS YP_002997718.1 251783413 8112519 complement(1956440..1958074) 1 NC_012891.1 similar to ABC transporter ATP-binding /membrane spanning permease - possible multidrug resistance [Carnobacterium sp. AT7]; ABC transporter ATP-binding protein/permease 1958074 8112519 SDEG_2023 Streptococcus dysgalactiae subsp. equisimilis GGS_124 ABC transporter ATP-binding protein/permease YP_002997718.1 1956440 R 486410 CDS YP_002997719.1 251783414 8112520 complement(1958059..1959042) 1 NC_012891.1 no hit; hypothetical protein 1959042 8112520 SDEG_2024 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002997719.1 1958059 R 486410 CDS YP_002997720.1 251783415 8112521 complement(1959917..1960780) 1 NC_012891.1 similar to transposase [Streptococcus pyogenes MGAS2096]; transposase 1960780 8112521 SDEG_2025 Streptococcus dysgalactiae subsp. equisimilis GGS_124 transposase YP_002997720.1 1959917 R 486410 CDS YP_002997721.1 251783416 8112522 complement(1961358..1961735) 1 NC_012891.1 similar to hypothetical protein M28 Spy0140 [Streptococcus pyogenes MGAS6180]; hypothetical protein 1961735 8112522 SDEG_2026 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002997721.1 1961358 R 486410 CDS YP_002997722.1 251783417 8112523 complement(1961986..1963710) 1 NC_012891.1 similar to streptolysin O precursor (Thiol-activated cytolysin); streptolysin O 1963710 slo 8112523 slo Streptococcus dysgalactiae subsp. equisimilis GGS_124 streptolysin O YP_002997722.1 1961986 R 486410 CDS YP_002997723.1 251783418 8110489 complement(1963725..1964210) 1 NC_012891.1 similar to streptococcal NAD glycohydrolase inhibitor [Streptococcus pyogenes MGAS10270]; streptococcal NAD glycohydrolase inhibitor 1964210 ifs 8110489 ifs Streptococcus dysgalactiae subsp. equisimilis GGS_124 streptococcal NAD glycohydrolase inhibitor YP_002997723.1 1963725 R 486410 CDS YP_002997724.1 251783419 8112048 complement(1964215..1965567) 1 NC_012891.1 similar to NADase [Streptococcus dysgalactiae subsp. equisimilis]; NADase 1965567 nga 8112048 nga Streptococcus dysgalactiae subsp. equisimilis GGS_124 NADase YP_002997724.1 1964215 R 486410 CDS YP_002997725.1 251783420 8111710 complement(1965924..1966478) 1 NC_012891.1 Modulates Rho-dependent transcription termination; transcription antitermination protein NusG 1966478 nusG 8111710 nusG Streptococcus dysgalactiae subsp. equisimilis GGS_124 transcription antitermination protein NusG YP_002997725.1 1965924 R 486410 CDS YP_002997726.1 251783421 8111727 complement(1966681..1966857) 1 NC_012891.1 forms a complex with SecY and SecG; SecYEG forms a protein-conducting channel to which secA binds and translocates targeted polypeptides across the cytoplasmic membrane, a process driven by ATP and a proton-motive force; preprotein translocase subunit SecE 1966857 secE 8111727 secE Streptococcus dysgalactiae subsp. equisimilis GGS_124 preprotein translocase subunit SecE YP_002997726.1 1966681 R 486410 CDS YP_002997727.1 251783422 8110478 complement(1966870..1967022) 1 NC_012891.1 in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group have the CXXC motif; 50S ribosomal protein L33 1967022 rpmG 8110478 rpmG Streptococcus dysgalactiae subsp. equisimilis GGS_124 50S ribosomal protein L33 YP_002997727.1 1966870 R 486410 CDS YP_002997728.1 251783423 8111084 complement(1967071..1969419) 1 NC_012891.1 similar to penicillin-binding protein 2a [Streptococcus pyogenes SSI-1]; penicillin-binding protein 2a 1969419 pbp2 8111084 pbp2 Streptococcus dysgalactiae subsp. equisimilis GGS_124 penicillin-binding protein 2a YP_002997728.1 1967071 R 486410 CDS YP_002997729.1 251783424 8111755 complement(1969458..1969838) 1 NC_012891.1 similar to translation initiation inhibitor [Streptococcus equi subsp. zooepidemicus MGCS10565]; translation initiation inhibitor 1969838 8111755 SDEG_2034 Streptococcus dysgalactiae subsp. equisimilis GGS_124 translation initiation inhibitor YP_002997729.1 1969458 R 486410 CDS YP_002997730.1 251783425 8112524 1970183..1970374 1 NC_012891.1 similar to hypothetical cytosolic protein [Streptococcus pyogenes MGAS10750]; hypothetical protein 1970374 8112524 SDEG_2035 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002997730.1 1970183 D 486410 CDS YP_002997731.1 251783426 8112525 1970244..1971269 1 NC_012891.1 similar to ribosomal large subunit pseudouridine synthase D [Streptococcus pyogenes MGAS6180]; ribosomal large subunit pseudouridine synthase D 1971269 8112525 SDEG_2036 Streptococcus dysgalactiae subsp. equisimilis GGS_124 ribosomal large subunit pseudouridine synthase D YP_002997731.1 1970244 D 486410 CDS YP_002997732.1 251783427 8112526 complement(1971371..1973008) 1 NC_012891.1 similar to hypothetical protein M5005 Spy 1757 [Streptococcus pyogenes MGAS5005]; hypothetical protein 1973008 8112526 SDEG_2037 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002997732.1 1971371 R 486410 CDS YP_002997733.1 251783428 8112527 1973289..1974785 1 NC_012891.1 similar to dipeptidase [Streptococcus pyogenes MGAS10270]; dipeptidase 1974785 8112527 SDEG_2038 Streptococcus dysgalactiae subsp. equisimilis GGS_124 dipeptidase YP_002997733.1 1973289 D 486410 CDS YP_002997734.1 251783429 8112528 1975118..1975585 1 NC_012891.1 similar to MutT/Nudix family protein [Streptococcus equi subsp. zooepidemicus MGCS10565]; MutT/Nudix family protein 1975585 8112528 SDEG_2039 Streptococcus dysgalactiae subsp. equisimilis GGS_124 MutT/Nudix family protein YP_002997734.1 1975118 D 486410 CDS YP_002997735.1 251783430 8112529 complement(1975802..1977427) 1 NC_012891.1 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth; chaperonin GroEL 1977427 groEL 8112529 groEL Streptococcus dysgalactiae subsp. equisimilis GGS_124 chaperonin GroEL YP_002997735.1 1975802 R 486410 CDS YP_002997736.1 251783431 8112019 complement(1977463..1977753) 1 NC_012891.1 10 kDa chaperonin; Cpn10; GroES; forms homoheptameric ring; binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it; folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES; release of the folded substrate is dependent on ATP binding and hydrolysis in the trans ring; co-chaperonin GroES 1977753 groES 8112019 groES Streptococcus dysgalactiae subsp. equisimilis GGS_124 co-chaperonin GroES YP_002997736.1 1977463 R 486410 CDS YP_002997737.1 251783432 8112020 complement(1977931..1980375) 1 NC_012891.1 similar to negative regulator of genetic competence clpC/mecB [Streptococcus pyogenes MGAS10270]; negative regulator of genetic competence clpC/mecB 1980375 clpC 8112020 clpC Streptococcus dysgalactiae subsp. equisimilis GGS_124 negative regulator of genetic competence clpC/mecB YP_002997737.1 1977931 R 486410 CDS YP_002997738.1 251783433 8111621 complement(1980375..1980836) 1 NC_012891.1 similar to transcriptional regulator ctsR [Streptococcus pyogenes MGAS2096]; transcriptional regulator ctsR 1980836 ctsR 8111621 ctsR Streptococcus dysgalactiae subsp. equisimilis GGS_124 transcriptional regulator ctsR YP_002997738.1 1980375 R 486410 CDS YP_002997739.1 251783434 8111653 complement(1981032..1981241) 1 NC_012891.1 similar to cold shock protein [Streptococcus pyogenes MGAS5005]; cold shock protein 1981241 csp 8111653 csp Streptococcus dysgalactiae subsp. equisimilis GGS_124 cold shock protein YP_002997739.1 1981032 R 486410 CDS YP_002997740.1 251783435 8111651 complement(1981399..1981887) 1 NC_012891.1 similar to transposase [Streptococcus criceti]; transposase 1981887 paaB 8111651 paaB Streptococcus dysgalactiae subsp. equisimilis GGS_124 transposase YP_002997740.1 1981399 R 486410 CDS YP_002997741.1 251783436 8111748 complement(1981842..1982261) 1 NC_012891.1 similar to transposase [Streptococcus pyogenes MGAS2096]; transposase 1982261 8111748 SDEG_2046 Streptococcus dysgalactiae subsp. equisimilis GGS_124 transposase YP_002997741.1 1981842 R 486410 CDS YP_002997742.1 251783437 8112530 1982761..1983309 1 NC_012891.1 similar to amidohydrolase 2 [Sphingomonas wittichii RW1]; amidohydrolase 2 1983309 8112530 SDEG_2047 Streptococcus dysgalactiae subsp. equisimilis GGS_124 amidohydrolase 2 YP_002997742.1 1982761 D 486410 CDS YP_002997743.1 251783438 8112531 1983340..1983588 1 NC_012891.1 similar to amidohydrolase 2 [Sphingomonas wittichii RW1]; amidohydrolase 2 1983588 8112531 SDEG_2048 Streptococcus dysgalactiae subsp. equisimilis GGS_124 amidohydrolase 2 YP_002997743.1 1983340 D 486410 CDS YP_002997744.1 251783439 8112532 complement(1983909..1984271) 1 NC_012891.1 similar to IS1562 transposase [Streptococcus pyogenes MGAS8232]; IS1562 transposase 1984271 tra 8112532 tra Streptococcus dysgalactiae subsp. equisimilis GGS_124 IS1562 transposase YP_002997744.1 1983909 R 486410 CDS YP_002997745.1 251783440 8111923 complement(1984383..1984727) 1 NC_012891.1 similar to transposase [Streptococcus pyogenes MGAS10394]; transposase 1984727 8111923 SDEG_2050 Streptococcus dysgalactiae subsp. equisimilis GGS_124 transposase YP_002997745.1 1984383 R 486410 CDS YP_002997746.1 251783441 8112533 complement(1984944..1985033) 1 NC_012891.1 similar to transposase [Streptococcus pyogenes MGAS10750]; transposase 1985033 8112533 SDEG_2051 Streptococcus dysgalactiae subsp. equisimilis GGS_124 transposase YP_002997746.1 1984944 R 486410 CDS YP_002997747.1 251783442 8112535 1985728..1986288 1 NC_012891.1 similar to alkyl hydroperoxidase [Streptococcus pyogenes M1 GAS]; alkyl hydroperoxidase 1986288 ahpC 8112535 ahpC Streptococcus dysgalactiae subsp. equisimilis GGS_124 alkyl hydroperoxidase YP_002997747.1 1985728 D 486410 CDS YP_002997748.1 251783443 8112317 1986309..1987841 1 NC_012891.1 similar to NADH dehydrogenase [Streptococcus pyogenes str. Manfredo]; NADH dehydrogenase 1987841 ahpF 8112317 ahpF Streptococcus dysgalactiae subsp. equisimilis GGS_124 NADH dehydrogenase YP_002997748.1 1986309 D 486410 CDS YP_002997749.1 251783444 8112318 complement(1987899..1989185) 1 NC_012891.1 catalyzing the hydrolysis of 4-imidazolone-5-propionate to N-formimidoyl-L-glutamate, the third step in the histidine degradation pathway; imidazolonepropionase 1989185 hutI 8112318 hutI Streptococcus dysgalactiae subsp. equisimilis GGS_124 imidazolonepropionase YP_002997749.1 1987899 R 486410 CDS YP_002997750.1 251783445 8112043 1989541..1991571 1 NC_012891.1 catalyzes the formation of 4-imidazolone-5-propanoate from urocanate during histidine metabolism; urocanate hydratase 1991571 hutU 8112043 hutU Streptococcus dysgalactiae subsp. equisimilis GGS_124 urocanate hydratase YP_002997750.1 1989541 D 486410 CDS YP_002997751.1 251783446 8112044 1991660..1992559 1 NC_012891.1 similar to glutamate formiminotransferase [Streptococcus pyogenes MGAS10394]; glutamate formiminotransferase 1992559 8112044 SDEG_2057 Streptococcus dysgalactiae subsp. equisimilis GGS_124 glutamate formiminotransferase YP_002997751.1 1991660 D 486410 CDS YP_002997752.1 251783447 8112536 1992570..1993196 1 NC_012891.1 similar to formiminotetrahydrofolate cyclodeaminase [Streptococcus pyogenes MGAS2096]; formiminotetrahydrofolate cyclodeaminase 1993196 8112536 SDEG_2058 Streptococcus dysgalactiae subsp. equisimilis GGS_124 formiminotetrahydrofolate cyclodeaminase YP_002997752.1 1992570 D 486410 CDS YP_002997753.1 251783448 8112537 1993214..1994887 1 NC_012891.1 catalyzes the formation of 10-formyltetrahydrofolate from formate and tetrahydrofolate; formate--tetrahydrofolate ligase 1994887 fhs2 8112537 fhs2 Streptococcus dysgalactiae subsp. equisimilis GGS_124 formate--tetrahydrofolate ligase YP_002997753.1 1993214 D 486410 CDS YP_002997754.1 251783449 8111891 1994909..1995505 1 NC_012891.1 similar to hypothetical protein spyM18 2145 [Streptococcus pyogenes MGAS8232]; hypothetical protein 1995505 8111891 SDEG_2060 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002997754.1 1994909 D 486410 CDS YP_002997755.1 251783450 8112538 1995734..1997077 1 NC_012891.1 similar to aminoacid permease [Streptococcus pyogenes MGAS10394]; amino acid permease 1997077 8112538 SDEG_2061 Streptococcus dysgalactiae subsp. equisimilis GGS_124 amino acid permease YP_002997755.1 1995734 D 486410 CDS YP_002997756.1 251783451 8112539 1997089..1998630 1 NC_012891.1 catalyzes the degradation of histidine to urocanate and ammmonia; histidine ammonia-lyase 1998630 hutH 8112539 hutH Streptococcus dysgalactiae subsp. equisimilis GGS_124 histidine ammonia-lyase YP_002997756.1 1997089 D 486410 CDS YP_002997757.1 251783452 8112042 1998807..1999802 1 NC_012891.1 catalyzes the formation of glutamate and formamide from N-formimidoyl-L-glutamate; formimidoylglutamase 1999802 hutG 8112042 hutG Streptococcus dysgalactiae subsp. equisimilis GGS_124 formimidoylglutamase YP_002997757.1 1998807 D 486410 CDS YP_002997758.1 251783453 8112041 complement(1999833..2002907) 1 NC_012891.1 similar to transcriptional regulator LuxR family [Streptococcus pyogenesMGAS10750]; LuxR family transcriptional regulator 2002907 8112041 SDEG_2064 Streptococcus dysgalactiae subsp. equisimilis GGS_124 LuxR family transcriptional regulator YP_002997758.1 1999833 R 486410 CDS YP_002997759.1 251783454 8112540 2003166..2003933 1 NC_012891.1 one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit; 30S ribosomal protein S2 2003933 rpsB 8112540 rpsB Streptococcus dysgalactiae subsp. equisimilis GGS_124 30S ribosomal protein S2 YP_002997759.1 2003166 D 486410 CDS YP_002997760.1 251783455 8111094 2004067..2005107 1 NC_012891.1 EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu; elongation factor Ts 2005107 tsf 8111094 tsf Streptococcus dysgalactiae subsp. equisimilis GGS_124 elongation factor Ts YP_002997760.1 2004067 D 486410 CDS YP_002997761.1 251783456 8111935 complement(2005274..2007169) 1 NC_012891.1 similar to oligoendopeptidase O [Streptococcus pyogenes MGAS2096]; oligoendopeptidase O 2007169 pepO 8111935 pepO Streptococcus dysgalactiae subsp. equisimilis GGS_124 oligoendopeptidase O YP_002997761.1 2005274 R 486410 CDS YP_002997762.1 251783457 8111278 complement(2007377..2009005) 1 NC_012891.1 similar to trehalose-6-phosphate hydrolase [Streptococcus pyogenes MGAS2096]; trehalose-6-phosphate hydrolase 2009005 dexS 8111278 dexS Streptococcus dysgalactiae subsp. equisimilis GGS_124 trehalose-6-phosphate hydrolase YP_002997762.1 2007377 R 486410 CDS YP_002997763.1 251783458 8111670 complement(2009072..2011096) 1 NC_012891.1 similar to PTS system trehalose-specific IIBC component / PTS system trehalose-specific IIA component [Streptococcus pyogenes MGAS2096]; PTS system trehalose-specific transporter subunit IIABC 2011096 8111670 SDEG_2069 Streptococcus dysgalactiae subsp. equisimilis GGS_124 PTS system trehalose-specific transporter subunit IIABC YP_002997763.1 2009072 R 486410 CDS YP_002997764.1 251783459 8110772 2011307..2012020 1 NC_012891.1 similar to trehalose operon transcriptional repressor [Streptococcus pyogenes MGAS10394]; trehalose operon transcriptional repressor 2012020 8110772 SDEG_2070 Streptococcus dysgalactiae subsp. equisimilis GGS_124 trehalose operon transcriptional repressor YP_002997764.1 2011307 D 486410 CDS YP_002997765.1 251783460 8110773 complement(2012299..2012538) 1 NC_012891.1 similar to hypothetical protein spyM18 2160 [Streptococcus pyogenes MGAS8232]; hypothetical protein 2012538 8110773 SDEG_2071 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002997765.1 2012299 R 486410 CDS YP_002997766.1 251783461 8110775 2013719..2014450 1 NC_012891.1 similar to hypothetical cytosolic protein [Streptococcus pyogenes MGAS10750]; hypothetical protein 2014450 yaaA 8110775 yaaA Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002997766.1 2013719 D 486410 CDS YP_002997767.1 251783462 8111956 complement(2014624..2015238) 1 NC_012891.1 similar to anaerobic ribonucleoside-triphosphate reductase activating protein [Streptococcus pyogenes MGAS10394]; anaerobic ribonucleoside-triphosphate reductase activating protein 2015238 nrdG 8111956 nrdG Streptococcus dysgalactiae subsp. equisimilis GGS_124 anaerobic ribonucleoside-triphosphate reductase activating protein YP_002997767.1 2014624 R 486410 CDS YP_002997768.1 251783463 8111720 complement(2015242..2015745) 1 NC_012891.1 similar to acetyltransferase [Streptococcus pyogenes MGAS10750]; acetyltransferase 2015745 8111720 SDEG_2075 Streptococcus dysgalactiae subsp. equisimilis GGS_124 acetyltransferase YP_002997768.1 2015242 R 486410 CDS YP_002997769.1 251783464 8110776 complement(2015754..2016689) 1 NC_012891.1 similar to Mvi [Streptococcus pyogenes MGAS10394]; virulence factor 2016689 8110776 SDEG_2076 Streptococcus dysgalactiae subsp. equisimilis GGS_124 virulence factor YP_002997769.1 2015754 R 486410 CDS YP_002997770.1 251783465 8110777 complement(2016718..2016864) 1 NC_012891.1 similar to hypothetical protein STRINF 00502 [Streptococcus infantarius subsp. infantarius ATCC BAA-102]; hypothetical protein 2016864 8110777 SDEG_2077 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002997770.1 2016718 R 486410 CDS YP_002997771.1 251783466 8110778 complement(2017050..2019248) 1 NC_012891.1 Catalyzes the reduction of nucleoside 5'-triphosphates to 2'-deoxynucleoside 5'-triphosphates; anaerobic ribonucleoside triphosphate reductase 2019248 nrdD 8110778 nrdD Streptococcus dysgalactiae subsp. equisimilis GGS_124 anaerobic ribonucleoside triphosphate reductase YP_002997771.1 2017050 R 486410 CDS YP_002997772.1 251783467 8111715 complement(2019345..2020907) 1 NC_012891.1 similar to hypothetical membrane spanning protein [Streptococcus pyogenes MGAS2096]; hypothetical protein 2020907 8111715 SDEG_2079 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002997772.1 2019345 R 486410 CDS YP_002997773.1 251783468 8110779 complement(2021243..2021548) 1 NC_012891.1 similar to hypothetical cytosolic protein [Streptococcus pyogenes MGAS10750]; hypothetical protein 2021548 8110779 SDEG_2080 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002997773.1 2021243 R 486410 CDS YP_002997774.1 251783469 8110780 complement(2021559..2021978) 1 NC_012891.1 similar to Holliday junction resolvase-like protein [Streptococcus pyogenes MGAS8232]; Holliday junction resolvase-like protein 2021978 8110780 SDEG_2081 Streptococcus dysgalactiae subsp. equisimilis GGS_124 Holliday junction resolvase-like protein YP_002997774.1 2021559 R 486410 CDS YP_002997775.1 251783470 8110781 complement(2021975..2022244) 1 NC_012891.1 similar to hypothetical protein M6 Spy1796 [Streptococcus pyogenes MGAS10394]; hypothetical protein 2022244 8110781 SDEG_2082 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002997775.1 2021975 R 486410 CDS YP_002997776.1 251783471 8110782 complement(2022356..2022754) 1 NC_012891.1 the anti-alpha factor Spx interacts with RNA polymerase alpha subunit C-terminal domain in a region that interacts with the sigma 70 subunit and may interfere with activation of promoters; in Bacillus subtilis this protein is a substrate for ClpXP protease; blocks transcription of the competence regulatory gene encoded by the srf operon; regulates a number of genes involved in thiol homeostasis including trxA and trxB; monomeric member of ArsC family of proteins; does not bind DNA; contains a disulfide bond between C10 and C13 which may sense disulfide stress; transcriptional regulator Spx 2022754 spxA 8110782 spxA Streptococcus dysgalactiae subsp. equisimilis GGS_124 transcriptional regulator Spx YP_002997776.1 2022356 R 486410 CDS YP_002997777.1 251783472 8110502 complement(2023048..2024184) 1 NC_012891.1 catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs; recombinase A 2024184 recA 8110502 recA Streptococcus dysgalactiae subsp. equisimilis GGS_124 recombinase A YP_002997777.1 2023048 R 486410 CDS YP_002997778.1 251783473 8111031 complement(2024289..2025560) 1 NC_012891.1 similar to colligrin [Streptococcus pyogenes MGAS10270]; competence damage-inducible protein A 2025560 cinA 8111031 cinA Streptococcus dysgalactiae subsp. equisimilis GGS_124 competence damage-inducible protein A YP_002997778.1 2024289 R 486410 CDS YP_002997779.1 251783474 8111614 complement(2025684..2026040) 1 NC_012891.1 similar to glyoxalase family protein superfamily [Streptococcus gordonii str. Challis substr. CH1]; glyoxalase 2026040 8111614 SDEG_2086 Streptococcus dysgalactiae subsp. equisimilis GGS_124 glyoxalase YP_002997779.1 2025684 R 486410 CDS YP_002997780.1 251783475 8110783 complement(2026040..2026612) 1 NC_012891.1 similar to DNA-3-methyladenine glycosylase I [Streptococcus pyogenes str. Manfredo]; DNA-3-methyladenine glycosylase I 2026612 tag 8110783 tag Streptococcus dysgalactiae subsp. equisimilis GGS_124 DNA-3-methyladenine glycosylase I YP_002997780.1 2026040 R 486410 CDS YP_002997781.1 251783476 8110512 complement(2026622..2027215) 1 NC_012891.1 plays an essential role in ATP-dependent branch migration of the Holliday junction; Holliday junction DNA helicase RuvA 2027215 ruvA 8110512 ruvA Streptococcus dysgalactiae subsp. equisimilis GGS_124 Holliday junction DNA helicase RuvA YP_002997781.1 2026622 R 486410 CDS YP_002997782.1 251783477 8110451 complement(2027217..2028437) 1 NC_012891.1 similar to transporter protein [Streptococcus pyogenes str. Manfredo]; transporter protein 2028437 lmrP 8110451 lmrP Streptococcus dysgalactiae subsp. equisimilis GGS_124 transporter protein YP_002997782.1 2027217 R 486410 CDS YP_002997783.1 251783478 8110905 complement(2028448..2030430) 1 NC_012891.1 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. Promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex; DNA mismatch repair protein 2030430 mutL 8110905 mutL Streptococcus dysgalactiae subsp. equisimilis GGS_124 DNA mismatch repair protein YP_002997783.1 2028448 R 486410 CDS YP_002997784.1 251783479 8111693 complement(2030558..2033113) 1 NC_012891.1 This protein performs the mismatch recognition step during the DNA repair process; DNA mismatch repair protein MutS 2033113 mutS 8111693 mutS Streptococcus dysgalactiae subsp. equisimilis GGS_124 DNA mismatch repair protein MutS YP_002997784.1 2030558 R 486410 CDS YP_002997785.1 251783480 8111695 complement(2033100..2033453) 1 NC_012891.1 similar to hypothetical protein Sez 1884 [Streptococcus equi subsp. zooepidemicus MGCS10565]; hypothetical protein 2033453 8111695 SDEG_2092 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002997785.1 2033100 R 486410 CDS YP_002997786.1 251783481 8110784 complement(2033450..2033887) 1 NC_012891.1 similar to arginine repressor [Streptococcus pyogenes MGAS5005]; arginine repressor 2033887 argR2 8110784 argR2 Streptococcus dysgalactiae subsp. equisimilis GGS_124 arginine repressor YP_002997786.1 2033450 R 486410 CDS YP_002997787.1 251783482 8112336 2034176..2035867 1 NC_012891.1 catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase; arginyl-tRNA synthetase 2035867 argS 8112336 argS Streptococcus dysgalactiae subsp. equisimilis GGS_124 arginyl-tRNA synthetase YP_002997787.1 2034176 D 486410 CDS YP_002997788.1 251783483 8112337 complement(2035937..2037334) 1 NC_012891.1 similar to ABC transporter ATP-binding protein [Streptococcus equi subsp. zooepidemicus MGCS10565]; ABC transporter ATP-binding protein 2037334 msrA 8112337 msrA Streptococcus dysgalactiae subsp. equisimilis GGS_124 ABC transporter ATP-binding protein YP_002997788.1 2035937 R 486410 CDS YP_002997789.1 251783484 8110945 complement(2037512..2038426) 1 NC_012891.1 similar to transporter [Streptococcus equi subsp. zooepidemicus MGCS10565]; transporter 2038426 8110945 SDEG_2096 Streptococcus dysgalactiae subsp. equisimilis GGS_124 transporter YP_002997789.1 2037512 R 486410 CDS YP_002997790.1 251783485 8110785 complement(2038456..2039355) 1 NC_012891.1 similar to hypothetical membrane spanning protein [Streptococcus pyogenes MGAS10394]; hypothetical protein 2039355 8110785 SDEG_2097 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002997790.1 2038456 R 486410 CDS YP_002997791.1 251783486 8110786 complement(2039376..2040317) 1 NC_012891.1 similar to hypothetical membrane spanning protein [Streptococcus pyogenes MGAS5005]; hypothetical protein 2040317 8110786 SDEG_2098 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002997791.1 2039376 R 486410 CDS YP_002997792.1 251783487 8110787 complement(2040310..2042058) 1 NC_012891.1 catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes; aspartyl-tRNA synthetase 2042058 aspS 8110787 aspS Streptococcus dysgalactiae subsp. equisimilis GGS_124 aspartyl-tRNA synthetase YP_002997792.1 2040310 R 486410 CDS YP_002997793.1 251783488 8112353 complement(2042396..2043676) 1 NC_012891.1 catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG; histidyl-tRNA synthetase 2043676 hisS 8112353 hisS Streptococcus dysgalactiae subsp. equisimilis GGS_124 histidyl-tRNA synthetase YP_002997793.1 2042396 R 486410 CDS YP_002997794.1 251783489 8112032 2044066..2044248 1 NC_012891.1 some L32 proteins have zinc finger motifs consisting of CXXC while others do not; 50S ribosomal protein L32 2044248 rpmF 8112032 rpmF Streptococcus dysgalactiae subsp. equisimilis GGS_124 50S ribosomal protein L32 YP_002997794.1 2044066 D 486410 CDS YP_002997795.1 251783490 8111083 2044264..2044413 1 NC_012891.1 in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif; 50S ribosomal protein L33 2044413 rpmG 8111083 rpmG Streptococcus dysgalactiae subsp. equisimilis GGS_124 50S ribosomal protein L33 YP_002997795.1 2044264 D 486410 CDS YP_002997796.1 251783491 8111085 2044705..2045319 1 NC_012891.1 similar to cadmium resistance protein [Streptococcus pyogenes MGAS5005]; cadmium resistance protein 2045319 cadD 8111085 cadD Streptococcus dysgalactiae subsp. equisimilis GGS_124 cadmium resistance protein YP_002997796.1 2044705 D 486410 CDS YP_002997797.1 251783492 8111600 2045301..2045669 1 NC_012891.1 similar to cadmium efflux system accessory protein [Streptococcus pyogenes MGAS5005]; cadmium efflux system accessory protein 2045669 cadC 8111600 cadC Streptococcus dysgalactiae subsp. equisimilis GGS_124 cadmium efflux system accessory protein YP_002997797.1 2045301 D 486410 CDS YP_002997798.1 251783493 8111599 2045692..2046636 1 NC_012891.1 similar to hypothetical protein MGAS10270 Spy1911 [Streptococcus pyogenes MGAS10270]; hypothetical protein 2046636 8111599 SDEG_2105 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002997798.1 2045692 D 486410 CDS YP_002997799.1 251783494 8110788 2046702..2047454 1 NC_012891.1 similar to FtsK/SpoIIIE family [Streptococcus pyogenes MGAS10750]; FtsK/SpoIIIE family 2047454 8110788 SDEG_2106 Streptococcus dysgalactiae subsp. equisimilis GGS_124 FtsK/SpoIIIE family YP_002997799.1 2046702 D 486410 CDS YP_002997800.1 251783495 8110789 2047451..2048053 1 NC_012891.1 similar to hypothetical protein SPy 2166 [Streptococcus pyogenes M1 GAS]; hypothetical protein 2048053 8110789 SDEG_2107 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002997800.1 2047451 D 486410 CDS YP_002997801.1 251783496 8110790 complement(2048531..2048815) 1 NC_012891.1 similar to transcriptional regulator [Streptococcus pyogenes MGAS2096]; transcriptional regulator 2048815 8110790 SDEG_2108 Streptococcus dysgalactiae subsp. equisimilis GGS_124 transcriptional regulator YP_002997801.1 2048531 R 486410 CDS YP_002997802.1 251783497 8110791 complement(2049023..2049181) 1 NC_012891.1 similar to hypothetical protein M6 Spy1842 [Streptococcus pyogenes MGAS10394]; hypothetical protein 2049181 8110791 SDEG_2109 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002997802.1 2049023 R 486410 CDS YP_002997803.1 251783498 8110792 2049266..2050108 1 NC_012891.1 similar to integral membrane protein [Streptococcus pyogenes MGAS6180]; integral membrane protein 2050108 8110792 SDEG_2110 Streptococcus dysgalactiae subsp. equisimilis GGS_124 integral membrane protein YP_002997803.1 2049266 D 486410 CDS YP_002997804.1 251783499 8110793 complement(2050155..2050796) 1 NC_012891.1 similar to NUDIX hydrolase [Streptococcus pyogenes str. Manfredo]; NUDIX hydrolase 2050796 8110793 SDEG_2111 Streptococcus dysgalactiae subsp. equisimilis GGS_124 NUDIX hydrolase YP_002997804.1 2050155 R 486410 CDS YP_002997805.1 251783500 8110794 2051000..2051326 1 NC_012891.1 similar to hypothetical protein SpyM3 1828 [Streptococcus pyogenes MGAS315]; hypothetical protein 2051326 8110794 SDEG_2112 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002997805.1 2051000 D 486410 CDS YP_002997806.1 251783501 8110795 2051313..2051900 1 NC_012891.1 similar to hypothetical membrane associated protein [Streptococcus pyogenes MGAS9429]; hypothetical protein 2051900 8110795 SDEG_2113 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002997806.1 2051313 D 486410 CDS YP_002997807.1 251783502 8110796 2051897..2052970 1 NC_012891.1 similar to hypothetical membrane associated protein [Streptococcus pyogenes MGAS2096]; hypothetical protein 2052970 8110796 SDEG_2114 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002997807.1 2051897 D 486410 CDS YP_002997808.1 251783503 8110797 complement(2053095..2055389) 1 NC_012891.1 similar to phage protein [Streptococcus pyogenes MGAS6180]; phage protein 2055389 8110797 SDEG_2115 Streptococcus dysgalactiae subsp. equisimilis GGS_124 phage protein YP_002997808.1 2053095 R 486410 CDS YP_002997809.1 251783504 8110798 2055503..2056036 1 NC_012891.1 similar to transcriptional regulator (TetR/AcrR family) [Streptococcus pyogenes MGAS315]; TetR family transcriptional regulator 2056036 8110798 SDEG_2116 Streptococcus dysgalactiae subsp. equisimilis GGS_124 TetR family transcriptional regulator YP_002997809.1 2055503 D 486410 CDS YP_002997810.1 251783505 8110799 complement(2056033..2057442) 1 NC_012891.1 similar to transposase [Streptococcus pyogenes MGAS10394]; transposase 2057442 8110799 SDEG_2117 Streptococcus dysgalactiae subsp. equisimilis GGS_124 transposase YP_002997810.1 2056033 R 486410 CDS YP_002997811.1 251783506 8110800 complement(2057426..2057533) 1 NC_012891.1 similar to transposase [Streptococcus pyogenes MGAS10750]; transposase 2057533 8110800 SDEG_2118 Streptococcus dysgalactiae subsp. equisimilis GGS_124 transposase YP_002997811.1 2057426 R 486410 CDS YP_002997812.1 251783507 8110801 complement(2057961..2058245) 1 NC_012891.1 similar to RelE-domain protein [Streptococcus pyogenes MGAS6180]; RelE-domain-containing protein 2058245 8110801 SDEG_2119 Streptococcus dysgalactiae subsp. equisimilis GGS_124 RelE-domain-containing protein YP_002997812.1 2057961 R 486410 CDS YP_002997813.1 251783508 8110802 complement(2058220..2058492) 1 NC_012891.1 similar to RelB protein [Streptococcus pyogenes MGAS10270]; RelB protein 2058492 8110802 SDEG_2120 Streptococcus dysgalactiae subsp. equisimilis GGS_124 RelB protein YP_002997813.1 2058220 R 486410 CDS YP_002997814.1 251783509 8110803 complement(2058584..2058970) 1 NC_012891.1 similar to phage encoded transcriptional regulator ArpU family [Streptococcus pyogenes MGAS10394]; ArpU family phage encoded transcriptional regulator 2058970 8110803 SDEG_2121 Streptococcus dysgalactiae subsp. equisimilis GGS_124 ArpU family phage encoded transcriptional regulator YP_002997814.1 2058584 R 486410 CDS YP_002997815.1 251783510 8110804 complement(2058945..2059307) 1 NC_012891.1 similar to phage protein [Streptococcus pyogenes MGAS6180]; phage protein 2059307 8110804 SDEG_2122 Streptococcus dysgalactiae subsp. equisimilis GGS_124 phage protein YP_002997815.1 2058945 R 486410 CDS YP_002997816.1 251783511 8110805 complement(2059578..2059799) 1 NC_012891.1 similar to phage protein [Streptococcus pyogenes MGAS6180]; phage protein 2059799 8110805 SDEG_2123 Streptococcus dysgalactiae subsp. equisimilis GGS_124 phage protein YP_002997816.1 2059578 R 486410 CDS YP_002997817.1 251783512 8110806 complement(2059799..2060053) 1 NC_012891.1 similar to phage protein [Streptococcus pyogenes MGAS6180]; phage protein 2060053 8110806 SDEG_2124 Streptococcus dysgalactiae subsp. equisimilis GGS_124 phage protein YP_002997817.1 2059799 R 486410 CDS YP_002997818.1 251783513 8110807 complement(2060037..2060375) 1 NC_012891.1 similar to phage protein [Streptococcus pyogenes MGAS6180]; phage protein 2060375 8110807 SDEG_2125 Streptococcus dysgalactiae subsp. equisimilis GGS_124 phage protein YP_002997818.1 2060037 R 486410 CDS YP_002997819.1 251783514 8110808 complement(2060458..2060706) 1 NC_012891.1 similar to phage protein [Streptococcus pyogenes MGAS6180]; phage protein 2060706 8110808 SDEG_2126 Streptococcus dysgalactiae subsp. equisimilis GGS_124 phage protein YP_002997819.1 2060458 R 486410 CDS YP_002997820.1 251783515 8110809 complement(2060716..2061501) 1 NC_012891.1 similar to phage protein [Streptococcus pyogenes MGAS6180]; phage protein 2061501 8110809 SDEG_2127 Streptococcus dysgalactiae subsp. equisimilis GGS_124 phage protein YP_002997820.1 2060716 R 486410 CDS YP_002997821.1 251783516 8110810 complement(2061590..2061739) 1 NC_012891.1 similar to phage protein [Streptococcus pyogenes MGAS6180]; phage protein 2061739 8110810 SDEG_2128 Streptococcus dysgalactiae subsp. equisimilis GGS_124 phage protein YP_002997821.1 2061590 R 486410 CDS YP_002997822.1 251783517 8110811 complement(2061753..2061998) 1 NC_012891.1 similar to phage protein [Streptococcus pyogenes MGAS6180]; phage protein 2061998 8110811 SDEG_2129 Streptococcus dysgalactiae subsp. equisimilis GGS_124 phage protein YP_002997822.1 2061753 R 486410 CDS YP_002997823.1 251783518 8110812 complement(2061973..2062320) 1 NC_012891.1 similar to phage protein [Streptococcus pyogenes MGAS6180]; phage protein 2062320 8110812 SDEG_2130 Streptococcus dysgalactiae subsp. equisimilis GGS_124 phage protein YP_002997823.1 2061973 R 486410 CDS YP_002997824.1 251783519 8110813 complement(2062322..2062495) 1 NC_012891.1 similar to phage protein [Streptococcus phage 10270.4]; phage protein 2062495 8110813 SDEG_2131 Streptococcus dysgalactiae subsp. equisimilis GGS_124 phage protein YP_002997824.1 2062322 R 486410 CDS YP_002997825.1 251783520 8110814 complement(2062501..2062674) 1 NC_012891.1 similar to phage protein [Streptococcus pyogenes MGAS6180]; phage protein 2062674 8110814 SDEG_2132 Streptococcus dysgalactiae subsp. equisimilis GGS_124 phage protein YP_002997825.1 2062501 R 486410 CDS YP_002997826.1 251783521 8110815 complement(2062961..2064574) 1 NC_012891.1 similar to bacteriophage resistance protein [Streptococcus pyogenes MGAS10270]; bacteriophage resistance protein 2064574 8110815 SDEG_2133 Streptococcus dysgalactiae subsp. equisimilis GGS_124 bacteriophage resistance protein YP_002997826.1 2062961 R 486410 CDS YP_002997827.1 251783522 8110816 complement(2064564..2065085) 1 NC_012891.1 similar to phage protein [Streptococcus pyogenes MGAS10270]; phage protein 2065085 8110816 SDEG_2134 Streptococcus dysgalactiae subsp. equisimilis GGS_124 phage protein YP_002997827.1 2064564 R 486410 CDS YP_002997828.1 251783523 8110817 complement(2065095..2065463) 1 NC_012891.1 similar to phage protein [Streptococcus pyogenes MGAS10270]; phage protein 2065463 8110817 SDEG_2135 Streptococcus dysgalactiae subsp. equisimilis GGS_124 phage protein YP_002997828.1 2065095 R 486410 CDS YP_002997829.1 251783524 8110818 complement(2065687..2066019) 1 NC_012891.1 similar to phageprotein [Streptococcus pyogenes MGAS6180]; phage protein 2066019 8110818 SDEG_2136 Streptococcus dysgalactiae subsp. equisimilis GGS_124 phage protein YP_002997829.1 2065687 R 486410 CDS YP_002997830.1 251783525 8110819 complement(2066243..2066491) 1 NC_012891.1 similar to prophage antirepressor [Streptococcus pyogenes MGAS10270]; prophage antirepressor 2066491 8110819 SDEG_2137 Streptococcus dysgalactiae subsp. equisimilis GGS_124 prophage antirepressor YP_002997830.1 2066243 R 486410 CDS YP_002997831.1 251783526 8110820 complement(2066548..2067111) 1 NC_012891.1 similar to phage antirepressor protein [Streptococcus pyogenes MGAS10270]; phage antirepressor protein 2067111 8110820 SDEG_2138 Streptococcus dysgalactiae subsp. equisimilis GGS_124 phage antirepressor protein YP_002997831.1 2066548 R 486410 CDS YP_002997832.1 251783527 8110821 complement(2067127..2067315) 1 NC_012891.1 similar to phage protein [Streptococcus pyogenes MGAS10270]; phage protein 2067315 8110821 SDEG_2139 Streptococcus dysgalactiae subsp. equisimilis GGS_124 phage protein YP_002997832.1 2067127 R 486410 CDS YP_002997833.1 251783528 8110822 2067484..2067927 1 NC_012891.1 similar to phage transcriptional regulator Cro/CI family [Streptococcus phage 10270.5]; phage transcriptional regulator, Cro/CI family 2067927 8110822 SDEG_2140 Streptococcus dysgalactiae subsp. equisimilis GGS_124 phage transcriptional regulator, Cro/CI family YP_002997833.1 2067484 D 486410 CDS YP_002997834.1 251783529 8110823 2068238..2068762 1 NC_012891.1 no hit; hypothetical protein 2068762 8110823 SDEG_2141 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002997834.1 2068238 D 486410 CDS YP_002997835.1 251783530 8110824 2069006..2070169 1 NC_012891.1 similar to DNA integration/recombination /inversion protein [Streptococcus phage 10270.5]; DNA integration/recombination/inversion protein 2070169 8110824 SDEG_2142 Streptococcus dysgalactiae subsp. equisimilis GGS_124 DNA integration/recombination/inversion protein YP_002997835.1 2069006 D 486410 CDS YP_002997836.1 251783531 8110825 complement(2070326..2070937) 1 NC_012891.1 primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination; 30S ribosomal protein S4 2070937 rpsD 8110825 rpsD Streptococcus dysgalactiae subsp. equisimilis GGS_124 30S ribosomal protein S4 YP_002997836.1 2070326 R 486410 CDS YP_002997837.1 251783532 8111095 complement(2071746..2072018) 1 NC_012891.1 similar to hypothetical protein spyM18 2216 [Streptococcus pyogenes MGAS8232]; hypothetical protein 2072018 8111095 SDEG_2144 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002997837.1 2071746 R 486410 CDS YP_002997838.1 251783533 8110826 complement(2072034..2073410) 1 NC_012891.1 unwinds double stranded DNA; replicative DNA helicase 2073410 holB 8110826 holB Streptococcus dysgalactiae subsp. equisimilis GGS_124 replicative DNA helicase YP_002997838.1 2072034 R 486410 CDS YP_002997839.1 251783534 8112035 complement(2073431..2073883) 1 NC_012891.1 in Escherichia coli this protein is wrapped around the base of the L1 stalk; 50S ribosomal protein L9 2073883 rplI 8112035 rplI Streptococcus dysgalactiae subsp. equisimilis GGS_124 50S ribosomal protein L9 YP_002997839.1 2073431 R 486410 CDS YP_002997840.1 251783535 8111064 complement(2073880..2075856) 1 NC_012891.1 similar to phosphoesterase DHH family protein [Streptococcus pyogenes MGAS2096]; phosphoesterase, DHH family protein 2075856 8111064 SDEG_2147 Streptococcus dysgalactiae subsp. equisimilis GGS_124 phosphoesterase, DHH family protein YP_002997840.1 2073880 R 486410 CDS YP_002997841.1 251783536 8110827 complement(2075947..2077845) 1 NC_012891.1 GidA; glucose-inhibited cell division protein A; involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U) of the wobble uridine base in some tRNAs; tRNA uridine 5-carboxymethylaminomethyl modification protein GidA 2077845 gidA 8110827 gidA Streptococcus dysgalactiae subsp. equisimilis GGS_124 tRNA uridine 5-carboxymethylaminomethyl modification protein GidA YP_002997841.1 2075947 R 486410 CDS YP_002997842.1 251783537 8111992 complement(2077897..2078346) 1 NC_012891.1 similar to phosphohydrolase [Streptococcus pyogenes MGAS6180]; phosphohydrolase 2078346 8111992 SDEG_2149 Streptococcus dysgalactiae subsp. equisimilis GGS_124 phosphohydrolase YP_002997842.1 2077897 R 486410 CDS YP_002997843.1 251783538 8110828 complement(2078560..2079168) 1 NC_012891.1 similar to hypothetical protein SAG2143 [Streptococcus agalactiae 2603V/R]; hypothetical protein 2079168 8110828 SDEG_2150 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002997843.1 2078560 R 486410 CDS YP_002997844.1 251783539 8110829 complement(2079200..2080339) 1 NC_012891.1 catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs; tRNA-specific 2-thiouridylase MnmA 2080339 mnmA 8110829 mnmA Streptococcus dysgalactiae subsp. equisimilis GGS_124 tRNA-specific 2-thiouridylase MnmA YP_002997844.1 2079200 R 486410 CDS YP_002997845.1 251783540 8111928 2080612..2081289 1 NC_012891.1 similar to L-serinedehydratase beta subunit [Streptococcus pyogenes MGAS10750]; L-serine dehydratase subunit beta 2081289 sdhB 8111928 sdhB Streptococcus dysgalactiae subsp. equisimilis GGS_124 L-serine dehydratase subunit beta YP_002997845.1 2080612 D 486410 CDS YP_002997846.1 251783541 8110475 2081301..2082173 1 NC_012891.1 similar to L-serinedehydratase alpha subunit [Streptococcus pyogenes MGAS10270]; L-serine dehydratase subunit alpha 2082173 sdhA 8110475 sdhA Streptococcus dysgalactiae subsp. equisimilis GGS_124 L-serine dehydratase subunit alpha YP_002997846.1 2081301 D 486410 CDS YP_002997847.1 251783542 8110474 2082199..2082846 1 NC_012891.1 similar to phosphoglycolate phosphatase [Streptococcus equi subsp. zooepidemicus MGCS10565]; phosphoglycolate phosphatase 2082846 8110474 SDEG_2154 Streptococcus dysgalactiae subsp. equisimilis GGS_124 phosphoglycolate phosphatase YP_002997847.1 2082199 D 486410 CDS YP_002997848.1 251783543 8110830 complement(2082909..2083523) 1 NC_012891.1 similar to transglycosylase SLT domain family protein [Streptococcus pyogenes MGAS10394]; transglycosylase 2083523 8110830 SDEG_2155 Streptococcus dysgalactiae subsp. equisimilis GGS_124 transglycosylase YP_002997848.1 2082909 R 486410 CDS YP_002997849.1 251783544 8110831 complement(2083709..2084509) 1 NC_012891.1 similar to cobalt transport protein cbiQ [Streptococcus pyogenes MGAS10394]; cobalt transport protein cbiQ 2084509 8110831 SDEG_2156 Streptococcus dysgalactiae subsp. equisimilis GGS_124 cobalt transport protein cbiQ YP_002997849.1 2083709 R 486410 CDS YP_002997850.1 251783545 8110832 complement(2084502..2085344) 1 NC_012891.1 with CbiNQ forms the ABC transporter for cobalt import; Streptococcus has two adjacent copies of this gene; cobalt transporter ATP-binding subunit 2085344 cbiO 8110832 cbiO Streptococcus dysgalactiae subsp. equisimilis GGS_124 cobalt transporter ATP-binding subunit YP_002997850.1 2084502 R 486410 CDS YP_002997851.1 251783546 8110833 complement(2085320..2086159) 1 NC_012891.1 with CbiNQ forms the ABC transporter for cobalt import; Streptococcus has two adjacent copies of this gene; cobalt transporter ATP-binding subunit 2086159 cbiO 8110833 cbiO Streptococcus dysgalactiae subsp. equisimilis GGS_124 cobalt transporter ATP-binding subunit YP_002997851.1 2085320 R 486410 CDS YP_002997852.1 251783547 8110834 complement(2086162..2086704) 1 NC_012891.1 similar to CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase PgsA [Streptococcus equi subsp. zooepidemicus MGCS10565]; CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase 2086704 pgsA 8110834 pgsA Streptococcus dysgalactiae subsp. equisimilis GGS_124 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase YP_002997852.1 2086162 R 486410 CDS YP_002997853.1 251783548 8111288 complement(2086718..2087749) 1 NC_012891.1 similar to hypothetical membrane associated protein [Streptococcus pyogenes MGAS6180]; hypothetical protein 2087749 8111288 SDEG_2160 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002997853.1 2086718 R 486410 CDS YP_002997854.1 251783549 8110835 complement(2087799..2089082) 1 NC_012891.1 similar to zinc protease [Streptococcus pyogenes MGAS10750]; zinc protease 2089082 8110835 SDEG_2161 Streptococcus dysgalactiae subsp. equisimilis GGS_124 zinc protease YP_002997854.1 2087799 R 486410 CDS YP_002997855.1 251783550 8110836 complement(2089084..2090328) 1 NC_012891.1 similar to zinc protease [Streptococcus pyogenes MGAS10394]; zinc protease 2090328 8110836 SDEG_2162 Streptococcus dysgalactiae subsp. equisimilis GGS_124 zinc protease YP_002997855.1 2089084 R 486410 CDS YP_002997856.1 251783551 8110837 2090436..2091050 1 NC_012891.1 similar to hypothetical cytosolic protein [Streptococcus pyogenes MGAS10750]; hypothetical protein 2091050 8110837 SDEG_2163 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002997856.1 2090436 D 486410 CDS YP_002997857.1 251783552 8110838 2091052..2092158 1 NC_012891.1 Required for DNA replication; binds preferentially to single-stranded, linear DNA; recombination protein F 2092158 recF 8110838 recF Streptococcus dysgalactiae subsp. equisimilis GGS_124 recombination protein F YP_002997857.1 2091052 D 486410 CDS YP_002997858.1 251783553 8111033 complement(2092215..2093078) 1 NC_012891.1 similar to glucose uptake family protein [Streptococcus pyogenes MGAS9429]; glucose uptake family protein 2093078 8111033 SDEG_2165 Streptococcus dysgalactiae subsp. equisimilis GGS_124 glucose uptake family protein YP_002997858.1 2092215 R 486410 CDS YP_002997859.1 251783554 8110839 complement(2093290..2094771) 1 NC_012891.1 catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate; inosine 5'-monophosphate dehydrogenase 2094771 guaB 8110839 guaB Streptococcus dysgalactiae subsp. equisimilis GGS_124 inosine 5'-monophosphate dehydrogenase YP_002997859.1 2093290 R 486410 CDS YP_002997860.1 251783555 8112023 complement(2094988..2096013) 1 NC_012891.1 catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; tryptophanyl-tRNA synthetase II 2096013 trsA 8112023 trsA Streptococcus dysgalactiae subsp. equisimilis GGS_124 tryptophanyl-tRNA synthetase II YP_002997860.1 2094988 R 486410 CDS YP_002997861.1 251783556 8111929 complement(2096155..2096232) 1 NC_012891.1 similar to hypothetical protein M6 Spy1877 [Streptococcus pyogenes MGAS10394]; hypothetical protein 2096232 8111929 SDEG_2168 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002997861.1 2096155 R 486410 CDS YP_002997862.1 251783557 8110840 2096436..2097308 1 NC_012891.1 similar to hypothetical protein SPy 2209 [Streptococcus pyogenes M1 GAS]; hypothetical protein 2097308 8110840 SDEG_2169 Streptococcus dysgalactiae subsp. equisimilis GGS_124 hypothetical protein YP_002997862.1 2096436 D 486410 CDS YP_002997863.1 251783558 8110841 2097387..2099006 1 NC_012891.1 similar to ABC transporter ATP-binding protein [Streptococcus pyogenes str. Manfredo]; ABC transporter ATP-binding protein 2099006 8110841 SDEG_2170 Streptococcus dysgalactiae subsp. equisimilis GGS_124 ABC transporter ATP-binding protein YP_002997863.1 2097387 D 486410 CDS YP_002997864.1 251783559 8110842 2099091..2101700 1 NC_012891.1 similar to ABC transporter permease protein [Streptococcus pyogenes MGAS10270]; ABC transporter permease 2101700 8110842 SDEG_2171 Streptococcus dysgalactiae subsp. equisimilis GGS_124 ABC transporter permease YP_002997864.1 2099091 D 486410 CDS YP_002997865.1 251783560 8110845 2102464..2103309 1 NC_012891.1 similar to insertion sequence IS1239 transposase [Streptococcus pyogenes str. Manfredo]; IS1239, transposase 2103309 8110845 SDEG_2174 Streptococcus dysgalactiae subsp. equisimilis GGS_124 IS1239, transposase YP_002997865.1 2102464 D 486410 CDS YP_002997866.1 251783561 8110847 complement(2103552..2104031) 1 NC_012891.1 SPOUT methyltransferase family protein; crystal structure shows homodimer; in Escherichia coli this protein methylates pseudouridine at position 1915 of the 23S ribosomal RNA; rRNA large subunit methyltransferase 2104031 8110847 SDEG_2176 Streptococcus dysgalactiae subsp. equisimilis GGS_124 rRNA large subunit methyltransferase YP_002997866.1 2103552 R 486410 CDS YP_002997867.1 251783562 8110848 2104243..2105466 1 NC_012891.1 similar to endopeptidase DegP [Streptococcus pyogenes MGAS10750]; endopeptidase 2105466 htrA 8110848 htrA Streptococcus dysgalactiae subsp. equisimilis GGS_124 endopeptidase YP_002997867.1 2104243 D 486410 CDS YP_002997868.1 251783563 8112040 2105525..2106331 1 NC_012891.1 similar to chromosome partitioning protein [Streptococcus pyogenes MGAS6180]; chromosome partitioning protein 2106331 parB 8112040 parB Streptococcus dysgalactiae subsp. equisimilis GGS_124 chromosome partitioning protein YP_002997868.1 2105525 D 486410 CDS