-- dump date 20140620_081735 -- class Genbank::Feature -- table feature -- table main -- field 1 id -- field 2 type -- field 3 name -- field 4 contig -- field 5 start_pos -- field 6 end_pos -- field 7 strand -- field 8 description -- field 9 chrom_position -- field 10 organism -- field 11 GeneID -- header -- id type name contig start_pos end_pos strand description chrom_position organism GeneID 486410000001 SEQ_END SEQ_END NC_012891.1 2106340 2106340 DR NC_012891.1; contig end 2106340..2106340 Streptococcus dysgalactiae subsp. equisimilis GGS_124 YP_002995770.1 CDS dnaA NC_012891.1 225 1580 D binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication; can also affect transcription of multiple genes including itself.; chromosomal replication initiation protein 225..1580 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111973 YP_002995771.1 CDS dnaN NC_012891.1 1734 2870 D binds the polymerase to DNA and acts as a sliding clamp; DNA polymerase III subunit beta 1734..2870 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111842 YP_002995772.1 CDS SDEG_0003 NC_012891.1 2944 3141 D similar to hypothetical cytosolic protein [Streptococcus pyogenes MGAS10394]; hypothetical protein 2944..3141 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111850 YP_002995773.1 CDS SDEG_0004 NC_012891.1 3398 3640 D similar to hypothetical protein gbs0005 [Streptococcus agalactiae NEM316]; hypothetical protein 3398..3640 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110853 YP_002995774.1 CDS SDEG_0005 NC_012891.1 3764 4879 D translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1; GTP-dependent nucleic acid-binding protein EngD 3764..4879 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110854 YP_002995775.1 CDS pth NC_012891.1 4950 5519 D Enables the recycling of peptidyl-tRNAs produced at termination of translation; peptidyl-tRNA hydrolase 4950..5519 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110855 YP_002995776.1 CDS trcF NC_012891.1 5522 9022 D similar to transcription-repair coupling factor [Streptococcus pyogenes SSI-1]; transcription-repair coupling factor 5522..9022 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111322 YP_002995777.1 CDS SDEG_0008 NC_012891.1 8970 10490 D similar to polysaccharide biosynthesis family protein [Streptococcus equi subsp. zooepidemicus MGCS10565]; polysaccharide biosynthesis protein 8970..10490 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111924 YP_002995778.1 CDS SDEG_0009 NC_012891.1 10525 10797 D similar to S4 domain protein [Streptococcus agalactiae 2603V/R]; S4 domain-containing protein 10525..10797 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110856 YP_002995779.1 CDS divIC NC_012891.1 10784 11155 D similar to cell division protein [Streptococcus pyogenes MGAS8232]; cell division protein 10784..11155 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110857 YP_002995780.1 CDS SDEG_0011 NC_012891.1 11155 11277 D similar to hypothetical protein M6 Spy0009 [Streptococcus pyogenes MGAS10394]; hypothetical protein 11155..11277 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111674 YP_002995781.1 CDS SDEG_0012 NC_012891.1 11290 12576 D similar to beta-lactamase [Streptococcus pyogenes MGAS2096]; beta-lactamase 11290..12576 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110858 YP_002995782.1 CDS tilS NC_012891.1 12573 13859 D similar to tRNA(Ile)-lysidine synthetase [Streptococcus pyogenes MGAS10394]; tRNA(Ile)-lysidine synthetase 12573..13859 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110859 YP_002995783.1 CDS hpt NC_012891.1 13864 14406 D similar to hypoxanthine- guaninephosphoribosyltransferase [Streptococcus pyogenesMGAS8232]; hypoxanthine-guanine phosphoribosyl transferase 13864..14406 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110523 YP_002995784.1 CDS ftsH NC_012891.1 14428 16413 D similar to cell division protein [Streptococcus pyogenes MGAS6180]; cell division protein 14428..16413 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112036 YP_002995785.1 CDS SDEG_0016 NC_012891.1 16541 17956 D similar to amino acid permease [Streptococcus pyogenes MGAS10394]; amino acid permease 16541..17956 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111916 YP_002995786.1 CDS sibA NC_012891.1 27115 28317 D similar to secreted protein [Streptococcus pyogenes MGAS2096]; hypothetical protein 27115..28317 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111772 YP_002995787.1 CDS prs1 NC_012891.1 28471 29433 D catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP; ribose-phosphate pyrophosphokinase 28471..29433 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110484 YP_002995788.1 CDS recO NC_012891.1 29658 30422 D involved in DNA repair and RecFOR pathway recombination; RecFOR proteins displace ssDNA-binding protein and facilitate the production of RecA-coated ssDNA; DNA repair protein RecO 29658..30422 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111313 YP_002995789.1 CDS plsX NC_012891.1 30529 31536 D involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsY; glycerol-3-phosphate acyltransferase PlsX 30529..31536 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111037 YP_002995790.1 CDS acpP.1 NC_012891.1 31529 31771 D carries the fatty acid chain in fatty acid biosynthesis; acyl carrier protein 31529..31771 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111296 YP_002995791.1 CDS purC NC_012891.1 31936 32646 D catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis; SAICAR synthase; phosphoribosylaminoimidazolesuccinocarboxamide synthase 31936..32646 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112304 YP_002995792.1 CDS SDEG_0044 NC_012891.1 32855 36580 D similar to phosphoribosyl formyl glycinamidine synthase [Streptococcus pyogenes MGAS2096]; phosphoribosyl formylglycin amidine synthase 32855..36580 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111332 YP_002995793.1 CDS purF NC_012891.1 36699 38150 D Catalyzes first step of the de novo purine nucleotide biosynthetic pathway; amidophosphoribosyltransferase 36699..38150 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111773 YP_002995794.1 CDS SDEG_0046 NC_012891.1 38300 39331 D catalyzes the formation of 1-(5-phosphoribosyl)-5-aminoimidazole from 2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in purine biosynthesis; phosphoribosylaminoimidazole synthetase 38300..39331 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111334 YP_002995795.1 CDS purN NC_012891.1 39324 39878 D glycinamide ribonucleotide transformylase; GAR Tfase; catalyzes the synthesis of 5'-phosphoribosylformylglycinamide from 5'-phosphoribosylglycinamide and 10-formyltetrahydrofolate; PurN requires formyl folate for the reaction unlike PurT which uses formate; phosphoribosylglycinamide formyltransferase 39324..39878 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111774 YP_002995796.1 CDS SDEG_0048 NC_012891.1 39976 40497 D similar to vanZ protein [Streptococcus pneumoniae TIGR4]; vanZ protein 39976..40497 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111335 YP_002995797.1 CDS purH NC_012891.1 40516 42060 D involved in de novo purine biosynthesis; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 40516..42060 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111775 YP_002995798.1 CDS SDEG_0050 NC_012891.1 42140 43267 R similar to autolysin [Streptococcus pyogenes MGAS5005]; autolysin complement(42140..43267) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111776 YP_002995799.1 CDS purD NC_012891.1 43551 44813 D catalyzes the formation of N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-D-ribosylamine and glycine in purine biosynthesis; phosphoribosylamine--glycine ligase 43551..44813 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111777 YP_002995800.1 CDS SDEG_0052 NC_012891.1 45452 45940 D similar to phosphoribosyl carboxyaminoimidazole (NCAIR) mutase [Streptococcus suis 98HAH33]; phosphoribosyl carboxyaminoimidazole (NCAIR) mutase 45452..45940 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111333 YP_002995801.1 CDS SDEG_0053 NC_012891.1 45927 47000 D With PurE catalyzes the conversion of aminoimidazole ribonucleotide to carboxyaminoimidazole ribonucleotide in the de novo purine nucleotide biosynthetic pathway; phosphoribosylaminoimidazole carboxylase ATPase subunit 45927..47000 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111778 YP_002995802.1 CDS SDEG_0054 NC_012891.1 47010 48266 D similar to hypothetical protein SGO 2086 [Streptococcus gordonii str. Challis substr. CH1]; hypothetical protein 47010..48266 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111779 YP_002995803.1 CDS purB NC_012891.1 48517 49809 D Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide; adenylosuccinate lyase 48517..49809 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111780 YP_002995804.1 CDS SDEG_0056 NC_012891.1 49951 50862 D similar to transcriptional regulator [Streptococcus pyogenes MGAS10750]; transcriptional regulator 49951..50862 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111331 YP_002995805.1 CDS ruvB NC_012891.1 51079 52095 D promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration; Holliday junction DNA helicase RuvB 51079..52095 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111781 YP_002995806.1 CDS SDEG_0058 NC_012891.1 52230 52661 D similar to protein tyrosine phosphatase [Streptococcus pyogenes MGAS10270]; protein tyrosine phosphatase 52230..52661 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110452 YP_002995807.1 CDS SDEG_0059 NC_012891.1 52690 53091 D similar to hypothetical membrane associated protein [Streptococcus pyogenes MGAS2096]; hypothetical protein 52690..53091 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111782 YP_002995808.1 CDS SDEG_0060 NC_012891.1 53088 54863 D similar to acyltransferase family [Streptococcus pyogenes MGAS6180]; acyltransferase family 53088..54863 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111783 YP_002995809.1 CDS adh2 NC_012891.1 55184 57826 D similar to alcohol dehydrogenase/acetaldehyde dehydrogenase (acetylating) [Streptococcus pyogenes MGAS5005]; bifunctional acetaldehyde-CoA/alcohol dehydrogenase 55184..57826 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111784 YP_002995810.1 CDS adhA NC_012891.1 58119 59135 D similar to zinc-dependent eukaryotic ADH enzymes and distinct from fermentative ADHs; alcohol dehydrogenase 58119..59135 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112311 YP_002995811.1 CDS thnsl NC_012891.1 59327 60811 D catalyzes the formation of L-threonine from O-phospho-L-homoserine; threonine synthase 59327..60811 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112312 YP_002995812.1 CDS SDEG_0064 NC_012891.1 60851 62140 D similar to Na+ driven multidrug efflux pump [Streptococcus pyogenes MGAS10394]; Na+ driven multidrug efflux pump 60851..62140 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110519 YP_002995813.1 CDS SDEG_0065 NC_012891.1 62109 63032 R similar to transposase [Streptococcus pyogenes MGAS10394]; transposase complement(62109..63032) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111785 YP_002995814.1 CDS SDEG_0066 NC_012891.1 62861 63184 R similar to transposase [Streptococcus pyogenes MGAS8232]; transposase complement(62861..63184) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111786 YP_002995815.1 CDS rpsJ NC_012891.1 63493 63801 D NusE; involved in assembly of the 30S subunit; in the ribosome, this protein is involved in the binding of tRNA; in Escherichia coli this protein was also found to be involved in transcription antitermination; NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination; binding of NusB/S10 to boxA nucleates assembly of the antitermination complex; 30S ribosomal protein S10 63493..63801 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111787 YP_002995816.1 CDS rplC NC_012891.1 63907 64533 D binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin; 50S ribosomal protein L3 63907..64533 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111101 YP_002995817.1 CDS rplD NC_012891.1 64557 65180 D L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA; 50S ribosomal protein L4 64557..65180 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111060 YP_002995818.1 CDS rplW NC_012891.1 65180 65476 D binds third domain of 23S rRNA and protein L29; part of exit tunnel; 50S ribosomal protein L23 65180..65476 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111061 YP_002995819.1 CDS rplB NC_012891.1 65494 66327 D one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation; 50S ribosomal protein L2 65494..66327 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111077 YP_002995820.1 CDS rpsS NC_012891.1 66418 66744 D similar to SSU ribosomal protein S19P [Streptococcus pyogenes MGAS2096]; 30S ribosomal protein S19 66418..66744 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111059 YP_002995821.1 CDS rplV NC_012891.1 66760 67104 D binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center; 50S ribosomal protein L22 66760..67104 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111110 YP_002995822.1 CDS rpsC NC_012891.1 67117 67770 D forms a complex with S10 and S14; binds the lower part of the 30S subunit head and the mRNA in the complete ribosome to position it for translation; 30S ribosomal protein S3 67117..67770 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111076 YP_002995823.1 CDS rplP NC_012891.1 67774 68187 D located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e; 50S ribosomal protein L16 67774..68187 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111788 YP_002995824.1 CDS SDEG_0076 NC_012891.1 68197 68403 D one of the stabilizing components for the large ribosomal subunit; 50S ribosomal protein L29 68197..68403 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111789 YP_002995825.1 CDS rpsQ NC_012891.1 68431 68691 D primary binding protein; helps mediate assembly; involved in translation fidelity; 30S ribosomal protein S17 68431..68691 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111790 YP_002995826.1 CDS rplN NC_012891.1 68716 69084 D binds to the 23S rRNA between the centers for peptidyl transferase and GTPase; 50S ribosomal protein L14 68716..69084 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111791 YP_002995827.1 CDS SDEG_0079 NC_012891.1 68721 68987 R similar to 50S ribosomal protein L14 [Staphylococcus epidermidis ATCC 12228]; 50S ribosomal protein L14 complement(68721..68987) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111068 YP_002995828.1 CDS rplX NC_012891.1 69168 69473 D assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel; 50S ribosomal protein L24 69168..69473 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111792 YP_002995829.1 CDS rplE NC_012891.1 69497 70039 D part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13; 50S ribosomal protein L5 69497..70039 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111078 YP_002995830.1 CDS rpsN NC_012891.1 70055 70240 D located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group appear to contain the zinc-binding motif; 30S ribosomal protein S14 70055..70240 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111062 YP_002995831.1 CDS rpsH NC_012891.1 70448 70846 D binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; 30S ribosomal protein S8 70448..70846 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111105 YP_002995832.1 CDS rplF NC_012891.1 71048 71584 D ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance; 50S ribosomal protein L6 71048..71584 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111099 YP_002995833.1 CDS rplR NC_012891.1 71680 72045 D binds 5S rRNA along with protein L5 and L25; 50S ribosomal protein L18 71680..72045 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111063 YP_002995834.1 CDS SDEG_0086 NC_012891.1 71857 72309 R similar to conserved hypothetical protein [Listeria monocytogenes str. 4b H7858]; hypothetical protein complement(71857..72309) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111071 YP_002995835.1 CDS rpsE NC_012891.1 72064 72558 D located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance; 30S ribosomal protein S5 72064..72558 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111793 YP_002995836.1 CDS SDEG_0088 NC_012891.1 72315 72629 R similar to ribosomal protein [Streptococcus agalactiae CJB111]; ribosomal protein complement(72315..72629) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111096 YP_002995837.1 CDS rpmD NC_012891.1 72573 72755 D L30 binds domain II of the 23S rRNA and the 5S rRNA; similar to eukaryotic protein L7; 50S ribosomal protein L30 72573..72755 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111794 YP_002995838.1 CDS rplO NC_012891.1 72970 73410 D late assembly protein; 50S ribosomal protein L15 72970..73410 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111081 YP_002995839.1 CDS secY NC_012891.1 73388 74731 D forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase; preprotein translocase subunit SecY 73388..74731 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111069 YP_002995840.1 CDS adk NC_012891.1 74878 75519 D similar to adenylate kinase Adk [Streptococcus equi subsp. zooepidemicus MGCS10565]; adenylate kinase 74878..75519 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110480 YP_002995841.1 CDS infA NC_012891.1 75583 75855 D stimulates the activities of the other two initiation factors, IF-2 and IF-3; translation initiation factor IF-1 75583..75855 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112313 YP_002995842.1 CDS rpmJ NC_012891.1 75881 75997 D smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group have the motif; 50S ribosomal protein L36 75881..75997 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112051 YP_002995843.1 CDS rpsM NC_012891.1 76015 76380 D located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA; 30S ribosomal protein S13 76015..76380 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111088 YP_002995844.1 CDS rpsK NC_012891.1 76398 76781 D located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3; 30S ribosomal protein S11 76398..76781 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111104 YP_002995845.1 CDS rpoA NC_012891.1 76827 77765 D catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme; DNA-directed RNA polymerase subunit alpha 76827..77765 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111102 YP_002995846.1 CDS rplQ NC_012891.1 77780 78166 D is a component of the macrolide binding site in the peptidyl transferase center; 50S ribosomal protein L17 77780..78166 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111089 YP_002995847.1 CDS SDEG_0099 NC_012891.1 78646 79482 D similar to transposase [Streptococcus pyogenes MGAS10394]; transposase 78646..79482 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111070 YP_002995848.1 CDS SDEG_0100 NC_012891.1 79570 80598 D similar to transposase [Streptococcus pyogenes MGAS10270]; transposase 79570..80598 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111795 YP_002995849.1 CDS SDEG_0117 NC_012891.1 87208 87747 D similar to nudix hydrolase [Streptococcus equi subsp. zooepidemicus MGCS10565]; nudix hydrolase 87208..87747 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111812 YP_002995850.1 CDS SDEG_0118 NC_012891.1 87882 88781 D catalyzes the formation of dimethylmenaquinone from 1,4-dihydroxy-2-naphthoate and octaprenyl diphosphate; 1,4-dihydroxy-2-naphthoate octaprenyltransferase 87882..88781 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111813 YP_002995851.1 CDS SDEG_0119 NC_012891.1 88778 90004 D similar to hypothetical protein gbs1788 [Streptococcus agalactiae NEM316]; hypothetical protein 88778..90004 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111814 YP_002995852.1 CDS cydA NC_012891.1 90114 91541 D similar to cytochrome d ubiquinol oxidase subunit II [Streptococcus agalactiae A909]; cytochrome d ubiquinol oxidase, subunit II 90114..91541 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111815 YP_002995853.1 CDS cydB NC_012891.1 91542 92561 D similar to cytochrome d ubiquinol oxidase subunit II [Streptococcus agalactiae 2603V/R]; cytochrome d ubiquinol oxidase, subunit II 91542..92561 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111655 YP_002995854.1 CDS SDEG_0122 NC_012891.1 92561 94276 D similar to hypothetical protein gbs1785 [Streptococcus agalactiae NEM316]; hypothetical protein 92561..94276 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111656 YP_002995855.1 CDS SDEG_0123 NC_012891.1 94273 96021 D similar to hypothetical protein gbs1784 [Streptococcus agalactiae NEM316]; hypothetical protein 94273..96021 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111816 YP_002995856.1 CDS SDEG_0124 NC_012891.1 96086 97066 R similar to hypothetical protein gbs1783 [Streptococcus agalactiae NEM316]; hypothetical protein complement(96086..97066) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111817 YP_002995857.1 CDS ipk NC_012891.1 97322 98173 D An essential enzyme in the nonmevalonate pathway of isopentenyl diphosphate and dimethylallyl diphosphate biosynthesis; 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase 97322..98173 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111818 YP_002995858.1 CDS adcR NC_012891.1 98242 98685 D similar to repressor protein [Streptococcus pyogenes MGAS315]; repressor protein 98242..98685 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110875 YP_002995859.1 CDS adcC NC_012891.1 98689 99408 D similar to ABC transporter (ATP-binding protein) [Streptococcus pyogenes MGAS315]; ABC transporter 98689..99408 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112309 YP_002995860.1 CDS adcB NC_012891.1 99362 100213 D similar to high-affinity zinc uptake system membrane protein znuB [Streptococcus pyogenes MGAS2096]; high-affinity zinc uptake system membrane protein 99362..100213 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112308 YP_002995861.1 CDS tyrS NC_012891.1 100262 101518 R catalyzes the formation of tyrosyl-tRNA(Tyr) from tyrosine and tRNA(Tyr); tyrosyl-tRNA synthetase complement(100262..101518) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112307 YP_002995862.1 CDS SDEG_0130 NC_012891.1 101613 103925 D similar to multimodular transpeptidase-transglycosylase [Streptococcus pyogenes MGAS10394]; multimodular transpeptidase-transglycosylase 101613..103925 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111937 YP_002995863.1 CDS rpoB NC_012891.1 104189 107755 D DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme; DNA-directed RNA polymerase subunit beta 104189..107755 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111819 YP_002995864.1 CDS rpoC NC_012891.1 107851 111492 D DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Subunit beta' binds to sigma factor allowing it to bind to the -10 region of the promoter; DNA-directed RNA polymerase subunit beta' 107851..111492 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111090 YP_002995865.1 CDS SDEG_0133 NC_012891.1 111695 112060 D similar to DNA binding protein [Streptococcus pyogenes MGAS8232]; DNA-binding protein 111695..112060 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111091 YP_002995866.1 CDS SDEG_0134 NC_012891.1 112141 113082 D similar to ComG operon protein 1 [Streptococcus pyogenes MGAS10394]; ComG operon protein 1 112141..113082 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111820 YP_002995867.1 CDS SDEG_0135 NC_012891.1 112958 114049 D similar to competence protein ABC transporter subunit [Streptococcus pyogenes MGAS8232]; competence protein, ABC transporter subunit 112958..114049 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111821 YP_002995868.1 CDS SDEG_0136 NC_012891.1 114051 114377 D similar to competence protein [Streptococcus pyogenes MGAS8232]; competence protein 114051..114377 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111822 YP_002995869.1 CDS SDEG_0137 NC_012891.1 114337 114780 D similar to competence protein [Streptococcus pyogenes MGAS315]; competence protein 114337..114780 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111823 YP_002995870.1 CDS SDEG_0138 NC_012891.1 114737 115033 D similar to hypothetical protein SpyM3 0082 [Streptococcus pyogenes MGAS315]; hypothetical protein 114737..115033 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111824 YP_002995871.1 CDS comYD NC_012891.1 115014 115454 D similar to comG operon protein 6 [Streptococcus pyogenes MGAS5005]; comG operon protein 6 115014..115454 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111825 YP_002995872.1 CDS SDEG_0140 NC_012891.1 115432 115806 D similar to comG operon protein 6 [Streptococcus pyogenes MGAS10750]; comG operon protein 6 115432..115806 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111638 YP_002995873.1 CDS SDEG_0141 NC_012891.1 115869 116822 D similar to adenine-specific methyltransferase [Streptococcus pyogenes MGAS2096]; adenine-specific methyltransferase 115869..116822 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111826 YP_002995874.1 CDS ackA NC_012891.1 116881 118077 D AckA utilizes acetate and can acetylate CheY which increases signal strength during flagellar rotation; utilizes magnesium and ATP; also involved in conversion of acetate to aceyl-CoA; acetate kinase 116881..118077 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111827 YP_002995875.1 CDS SDEG_0143 NC_012891.1 118384 118590 D similar to HTH-type transcriptional regulator [Streptococcus equi subsp. zooepidemicus MGCS10565]; HTH-type transcriptional regulator 118384..118590 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112298 YP_002995876.1 CDS SDEG_0144 NC_012891.1 118693 119373 D similar to membrane-bound protease CAAX family [Streptococcus equi subsp. zooepidemicus MGCS10565]; membrane-bound protease CAAX family 118693..119373 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111828 YP_002995877.1 CDS SDEG_0145 NC_012891.1 119391 119828 D similar to hypothetical protein Sez 1851 [Streptococcus equi subsp. zooepidemicus MGCS10565]; hypothetical protein 119391..119828 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111829 YP_002995878.1 CDS proC NC_012891.1 119967 120743 R catalyzes the formation of L-proline from pyrroline-5-carboxylate; pyrroline-5-carboxylate reductase complement(119967..120743) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111830 YP_002995879.1 CDS pepA NC_012891.1 120790 121857 R similar to glutamyl aminopeptidase [Streptococcus pyogenes MGAS10750]; glutamyl aminopeptidase complement(120790..121857) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111312 YP_002995880.1 CDS SDEG_0148 NC_012891.1 122032 122220 R similar to hypothetical protein MGAS10750 Spy0105 [Streptococcus pyogenes MGAS10750]; hypothetical protein complement(122032..122220) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111758 YP_002995881.1 CDS SDEG_0149 NC_012891.1 122407 122700 D similar to hypothetical membrane associated protein [Streptococcus pyogenes MGAS5005]; hypothetical protein 122407..122700 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111831 YP_002995882.1 CDS trxA NC_012891.1 122697 123014 D similar to thioredoxin [Streptococcus pyogenes MGAS8232]; thioredoxin 122697..123014 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111832 YP_002995883.1 CDS SDEG_0151 NC_012891.1 123032 123658 D similar to tRNA binding domain protein [Streptococcus pyogenes MGAS10394]; tRNA binding domain-containing protein 123032..123658 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111932 YP_002995884.1 CDS SDEG_0152 NC_012891.1 123810 124205 D binds to single stranded DNA and may facilitate the binding and interaction of other proteins to DNA; single-stranded DNA-binding protein 123810..124205 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111833 YP_002995885.1 CDS SDEG_0153 NC_012891.1 124465 125154 R similar to deoxyadenosine kinase [Streptococcus pyogenes MGAS10394]; deoxyadenosine kinase complement(124465..125154) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111834 YP_002995886.1 CDS SDEG_0154 NC_012891.1 125126 126190 R similar to tRNA-dihydrouridine synthase [Streptococcus pyogenes MGAS2096]; tRNA-dihydrouridine synthase complement(125126..126190) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111835 YP_002995887.1 CDS hslO NC_012891.1 126090 126962 R becomes active under oxidative stress; four conserved cysteines bind a zinc atom when they are in the reduced state and the enzyme is inactive; oxidative stress results in oxidized cysteines, release of zinc, and binding of Hsp33 to aggregation-prone proteins; forms dimers and higher order oligomers; Hsp33-like chaperonin complement(126090..126962) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111836 YP_002995888.1 CDS rofA NC_012891.1 127109 128701 R similar to transcriptional regulator RofA [Streptococcus pyogenes MGAS10750]; transcriptional regulator complement(127109..128701) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112038 YP_002995889.1 CDS fszF NC_012891.1 128883 130817 D similar to fimbrial subunit protein FszF [Streptococcus equi subsp. zooepidemicus MGCS10565]; fimbrial subunit protein 128883..130817 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111053 YP_002995890.1 CDS fszE NC_012891.1 130900 131844 D similar to T-antigen-like fimbrial structural subunit protein FszE [Streptococcus equi subsp. zooepidemicus MGCS10565]; T-antigen-like fimbrial structural subunit protein 130900..131844 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111913 YP_002995891.1 CDS SDEG_0159 NC_012891.1 131849 132727 D similar to sortase [Streptococcus pyogenes MGAS10270]; sortase 131849..132727 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111912 YP_002995892.1 CDS SDEG_0160 NC_012891.1 132711 133568 D similar to sortase [Streptococcus pyogenes MGAS10270]; sortase 132711..133568 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111837 YP_002995893.1 CDS SDEG_0161 NC_012891.1 133629 138743 D similar to fibronectin-binding protein [Streptococcus pyogenes MGAS10270]; fibronectin-binding protein 133629..138743 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111838 YP_002995894.1 CDS SDEG_0162 NC_012891.1 138808 139485 R similar to DNA-binding protein [Streptococcus pyogenes MGAS10394]; DNA-binding protein complement(138808..139485) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111839 YP_002995895.1 CDS SDEG_0163 NC_012891.1 139658 140023 D similar to translation initiation inhibitor [Streptococcus pyogenes MGAS10394]; translation initiation inhibitor 139658..140023 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111435 YP_002995896.1 CDS SDEG_0164 NC_012891.1 140049 141080 D similar to hypothetical protein SpyM50119 [Streptococcus pyogenes str. Manfredo]; hypothetical protein 140049..141080 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111436 YP_002995897.1 CDS SDEG_0165 NC_012891.1 141382 142644 R similar to tellurite resistance protein [Streptococcus pyogenes MGAS10394]; tellurite resistance protein complement(141382..142644) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111437 YP_002995898.1 CDS SDEG_0166 NC_012891.1 142657 143535 R similar to hypothetical membrane associated protein [Streptococcus pyogenes MGAS10394]; hypothetical protein complement(142657..143535) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111438 YP_002995899.1 CDS purA NC_012891.1 143964 145256 D catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis; adenylosuccinate synthetase 143964..145256 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111439 YP_002995900.1 CDS SDEG_0168 NC_012891.1 145582 146625 D similar to nucleoside-binding protein [Streptococcus pyogenes MGAS5005]; nucleoside-binding protein 145582..146625 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111330 YP_002995901.1 CDS SDEG_0169 NC_012891.1 146829 147602 R similar to pyruvate formate-lyase activating enzyme [Streptococcus pyogenes MGAS10394]; pyruvate formate-lyase activating enzyme complement(146829..147602) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111440 YP_002995902.1 CDS SDEG_0170 NC_012891.1 147725 148474 D similar to DeoR family transcriptional regulator [Streptococcus pyogenes MGAS10394]; DeoR family transcriptional regulator 147725..148474 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111441 YP_002995903.1 CDS SDEG_0171 NC_012891.1 148490 149470 D similar to sorbitol operon regulator [Streptococcus pyogenes MGAS10394]; sorbitol operon regulator 148490..149470 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111442 YP_002995904.1 CDS SDEG_0172 NC_012891.1 149750 150070 D similar to PTS system, cellobiose-specific IIA component [Streptococcus pyogenes MGAS5005]; PTS system cellobiose-specific transporter subunit IIA 149750..150070 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111443 YP_002995905.1 CDS SDEG_0173 NC_012891.1 150098 150406 D similar to PTS system, cellobiose-specific IIB component [Streptococcus pyogenes MGAS10750]; PTS system cellobiose-specific transporter subunit IIB 150098..150406 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111444 YP_002995906.1 CDS SDEG_0174 NC_012891.1 150416 151720 D similar to PTS system, cellobiose-specific IIB component [Streptococcus pyogenes MGAS10750]; PTS system cellobiose-specific transporter subunit IIC 150416..151720 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111445 YP_002995907.1 CDS SDEG_0175 NC_012891.1 151931 154348 D similar to formate acetyltransferase [Streptococcus pyogenes MGAS10394]; formate acetyltransferase 151931..154348 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111446 YP_002995908.1 CDS mipB NC_012891.1 154361 155029 D similar to transaldolase from Escherichia coli; many organisms have multiple copies; fructose-6-phosphate aldolase 154361..155029 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111447 YP_002995909.1 CDS gldA NC_012891.1 155071 156159 D forms dimers and octamers; involved in conversion of glycerol to dihydroxy-acetone; glycerol dehydrogenase 155071..156159 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110939 YP_002995910.1 CDS SDEG_0178 NC_012891.1 156347 156658 D similar to hypothetical protein SsuiDRAFT 0887 [Streptococcus suis 89/1591]; hypothetical protein 156347..156658 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111995 YP_002995911.1 CDS SDEG_0179 NC_012891.1 156731 157240 R similar to low temperature requirement C protein [Streptococcus pyogenes MGAS8232]; low temperature requirement C protein complement(156731..157240) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111448 YP_002995912.1 CDS SDEG_0180 NC_012891.1 157414 157965 D no hit; hypothetical protein 157414..157965 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111449 YP_002995913.1 CDS SDEG_0181 NC_012891.1 158072 159097 D similar to MccC family protein [Streptococcus pneumoniae D39]; MccC family protein 158072..159097 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111450 YP_002995914.1 CDS SDEG_0182 NC_012891.1 159237 160535 R similar to hypothetical protein PsycPRwf 0104 [Psychrobacter sp. PRwf-1]; hypothetical protein complement(159237..160535) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111451 YP_002995915.1 CDS SDEG_0183 NC_012891.1 160732 161220 D similar to YbaK / prolyl-tRNA synthetases associated domain; YbaK/prolyl-tRNA synthetases associated domain 160732..161220 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111452 YP_002995916.1 CDS SDEG_0184 NC_012891.1 161359 161628 R similar to predicted transcriptional regulator [Streptococcus suis 98HAH33]; transcriptional regulator complement(161359..161628) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111453 YP_002995917.1 CDS SDEG_0185 NC_012891.1 162212 163639 R similar to hypothetical protein SAG0685 [Streptococcus agalactiae 2603V/R]; hypothetical protein complement(162212..163639) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111454 YP_002995918.1 CDS SDEG_0186 NC_012891.1 163782 165293 R similar to ATPase components of ABC transporters with duplicated ATPase domains, multidrug transport system [Streptococcus sanguinis SK36]; ATPase components of ABC transporters complement(163782..165293) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111455 YP_002995919.1 CDS SDEG_0187 NC_012891.1 165566 166186 R similar to cyclic nucleotide-binding domain protein [Lactococcus lactis subsp. cremoris MG1363]; cyclic nucleotide-binding domain-containing protein complement(165566..166186) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111456 YP_002995920.1 CDS SDEG_0188 NC_012891.1 166263 166859 D similar to hypothetical protein llmg 1236 [Lactococcus lactis subsp. cremoris MG1363]; hypothetical protein 166263..166859 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111457 YP_002995921.1 CDS SDEG_0189 NC_012891.1 166869 167519 D similar to nucleotide-binding protein implicated in inhibition of septum formation [Streptococcus suis 98HAH33]; nucleotide-binding protein 166869..167519 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111458 YP_002995922.1 CDS SDEG_0190 NC_012891.1 167648 168001 R no hit; hypothetical protein complement(167648..168001) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111459 YP_002995923.1 CDS SDEG_0191 NC_012891.1 168818 169204 D similar to phosphoglycerate mutase family protein [Streptococcus equi subsp. zooepidemicus MGCS10565]; phosphoglycerate mutase 168818..169204 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111460 YP_002995924.1 CDS flaR NC_012891.1 169256 169762 R similar to topology modulation protein [Streptococcus pyogenes MGAS6180]; topology modulation protein complement(169256..169762) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111461 YP_002995925.1 CDS SDEG_0193 NC_012891.1 169817 170299 R similar to acetyltransferase [Streptococcus pyogenes MGAS10394]; acetyltransferase complement(169817..170299) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111898 YP_002995926.1 CDS SDEG_0194 NC_012891.1 170671 171699 D similar to transposase [Streptococcus pyogenes MGAS10270]; transposase 170671..171699 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111462 YP_002995927.1 CDS SDEG_0195 NC_012891.1 171832 173145 D similar to transcriptional regulator [Streptococcus equi subsp. zooepidemicus MGCS10565]; transcriptional regulator 171832..173145 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111463 YP_002995928.1 CDS SDEG_0196 NC_012891.1 173214 174878 D similar to bacteriocin ABC-type exporter ATP binding/permease protein [Streptococcus sanguinis SK36]; bacteriocin ABC-type exporter, ATP binding/permease 173214..174878 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111464 YP_002995929.1 CDS SDEG_0197 NC_012891.1 174898 175101 D similar to hypothetical protein M28 Spy1333 [Streptococcus pyogenes MGAS6180]; hypothetical protein 174898..175101 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111465 YP_002995930.1 CDS SDEG_0198 NC_012891.1 175341 176195 D similar to streptomycin resistance protein [Streptococcus agalactiae 2603V/R]; streptomycin resistance protein 175341..176195 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111466 YP_002995931.1 CDS SDEG_0199 NC_012891.1 176218 176778 D similar to phosphoglycerate mutase family protein [Streptococcus equi subsp. zooepidemicus MGCS10565]; phosphoglycerate mutase 176218..176778 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111467 YP_002995932.1 CDS SDEG_0200 NC_012891.1 177881 178147 D similar to transposase [Streptococcus pyogenes MGAS2096]; transposase 177881..178147 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111468 YP_002995933.1 CDS SDEG_0201 NC_012891.1 178226 178744 D similar to transposase [Streptococcus pyogenes MGAS2096]; transposase 178226..178744 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111469 YP_002995934.1 CDS SDEG_0202 NC_012891.1 178798 179526 D similar to hypothetical protein gbs1981 [Streptococcus agalactiae NEM316]; hypothetical protein 178798..179526 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111470 YP_002995935.1 CDS SDEG_0203 NC_012891.1 179957 180193 D similar to hypothetical protein M28 Spy1332 [Streptococcus pyogenes MGAS6180]; hypothetical protein 179957..180193 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111471 YP_002995936.1 CDS SDEG_0204 NC_012891.1 180639 181442 D similar to hypothetical protein M28 Spy1308 [Streptococcus pyogenes MGAS6180]; hypothetical protein 180639..181442 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111472 YP_002995937.1 CDS SDEG_0205 NC_012891.1 181483 182262 R similar to ISSdy1 transposase OrfB [Streptococcus agalactiae 2603V/R]; ISSdy1, transposase OrfB complement(181483..182262) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111473 YP_002995938.1 CDS SDEG_0206 NC_012891.1 182298 182588 R similar to ISSdy1 transposase OrfA [Streptococcus agalactiae 515]; ISSdy1, transposase OrfA complement(182298..182588) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111474 YP_002995939.1 CDS SDEG_0207 NC_012891.1 182811 184145 R similar to protein kinase, [Streptococcus pneumoniae TIGR4]; protein kinase complement(182811..184145) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111475 YP_002995940.1 CDS SDEG_0208 NC_012891.1 184142 184435 R similar to hypothetical protein SP 1060 [Streptococcus pneumoniae TIGR4]; hypothetical protein complement(184142..184435) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111476 YP_002995941.1 CDS SDEG_0209 NC_012891.1 184498 184737 R similar to hypothetical protein SP 1059 [Streptococcus pneumoniae TIGR4]; hypothetical protein complement(184498..184737) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111477 YP_002995942.1 CDS SDEG_0210 NC_012891.1 184881 185789 D similar to ABC transporter ATP-binding protein [Streptococcus pneumoniae TIGR4]; ABC transporter ATP-binding protein 184881..185789 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111478 YP_002995943.1 CDS SDEG_0211 NC_012891.1 185816 186616 D similar to ABC-2 transporter permease protein [Streptococcus pneumoniae TIGR4]; ABC transporter permease 185816..186616 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111479 YP_002995944.1 CDS SDEG_0212 NC_012891.1 186743 187378 D similar to transposase IS204/IS1001/IS1096/IS1165 [Streptococcus suis 89/1591]; transposase 186743..187378 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111480 YP_002995946.1 CDS cshA NC_012891.1 187820 189109 R similar to recombination factor protein RarA [Streptococcus thermophilus LMG 18311]; recombination factor protein RarA complement(187820..189109) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111482 YP_002995947.1 CDS SDEG_0216 NC_012891.1 189142 189708 R TrpG; with TrpE catalyzes the formation of anthranilate and glutamate from chorismate and glutamine; TrpG provides the glutamine amidotransferase activity; anthranilate synthase component II complement(189142..189708) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111650 YP_002995948.1 CDS SDEG_0217 NC_012891.1 189741 191504 R similar to para-aminobenzoate synthetase component I/4-amino-4-deoxychorismate lyase [Streptococcus pyogenes MGAS5005]; para-aminobenzoate synthetase componentI/4-amino-4-deoxychorismate lyase complement(189741..191504) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111483 YP_002995949.1 CDS SDEG_0218 NC_012891.1 191698 192168 D similar to hypothetical protein MGAS2096 Spy1717 [Streptococcus pyogenes MGAS2096]; hypothetical protein 191698..192168 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111484 YP_002995950.1 CDS prmA NC_012891.1 192239 193192 D methylates ribosomal protein L11 at multiple amino acid positions; mutations of these genes in Escherichia coli or Thermus thermophilus has no apparent phenotype; 50S ribosomal protein L11 methyltransferase 192239..193192 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111485 YP_002995951.1 CDS SDEG_0220 NC_012891.1 193192 193950 D in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA; cells lacking this function can grow, but are outcompeted by wild-type; SAM-dependent m(3)U1498 methyltransferase; 16S ribosomal RNA methyltransferase RsmE 193192..193950 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111486 YP_002995952.1 CDS SDEG_0221 NC_012891.1 194102 195124 D similar to HTH-type transcriptional regulator MalR-like [Streptococcus equi subsp. zooepidemicus MGCS10565]; HTH-type transcriptional regulator 194102..195124 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111487 YP_002995953.1 CDS SDEG_0222 NC_012891.1 195394 197580 D similar to PTS system glucose-specific IIABC component [Streptococcus pyogenes MGAS10394]; PTS system glucose-specific transporter subunit IIABC 195394..197580 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111488 YP_002995954.1 CDS rgfB NC_012891.1 197659 198483 D similar to RgfB protein [Streptococcus pyogenes MGAS315]; RgfB protein 197659..198483 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111489 YP_002995955.1 CDS SDEG_0224 NC_012891.1 198492 199004 R similar to hypothetical protein SAG1944 [Streptococcus agalactiae 2603V/R]; hypothetical protein complement(198492..199004) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111045 YP_002995956.1 CDS SDEG_0225 NC_012891.1 199028 200128 R similar to glucanase; deblocking aminopeptidase [Bacillus cereus E33L]; glucanase; deblocking aminopeptidase complement(199028..200128) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111490 YP_002995957.1 CDS SDEG_0226 NC_012891.1 200136 200687 R similar to hypothetical protein gbs0573 [Streptococcus agalactiae NEM316]; hypothetical protein complement(200136..200687) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111491 YP_002995958.1 CDS SDEG_0227 NC_012891.1 200691 201671 R similar to inosine-uridine preferring nucleoside hydrolase [Streptococcus agalactiae 2603V/R]; inosine-uridine preferring nucleoside hydrolase complement(200691..201671) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111492 YP_002995959.1 CDS nrdI NC_012891.1 201952 202419 R has a stimulatory effect on the ribonucleotide reductase activity of NrdH with NrdEF; flavoprotein NrdI complement(201952..202419) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111493 YP_002995960.1 CDS mgg NC_012891.1 202906 204447 D similar to trans-acting positive regulator [Streptococcus pyogenes MGAS10394]; trans-acting positive regulator 202906..204447 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111721 YP_002995961.1 CDS stg480.0 NC_012891.1 204718 206343 D similar to M protein; antiphagocytic M protein 204718..206343 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110937 YP_002995962.1 CDS SDEG_0231 NC_012891.1 206884 209103 D similar to GTP pyrophosphokinase [Streptococcus pyogenes MGAS10394]; GTP pyrophosphokinase 206884..209103 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110506 YP_002995963.1 CDS SDEG_0232 NC_012891.1 209117 209560 D hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr); possible defense mechanism against a harmful effect of D-tyrosine; D-tyrosyl-tRNA(Tyr) deacylase 209117..209560 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111494 YP_002995964.1 CDS SDEG_0233 NC_012891.1 209658 210980 R similar to streptokinase [Streptococcus pyogenes MGAS10394]; streptokinase complement(209658..210980) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111495 YP_002995965.1 CDS SDEG_0234 NC_012891.1 211267 212157 D similar to leucine rich protein [Streptococcus pyogenes MGAS10394]; hypothetical protein 211267..212157 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111496 YP_002995966.1 CDS SDEG_0235 NC_012891.1 212455 213588 D similar to multiple sugar transport ATP-binding protein [Streptococcus pyogenes MGAS10394]; multiple sugar transport ATP-binding protein 212455..213588 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111497 YP_002995967.1 CDS SDEG_0236 NC_012891.1 213664 215283 D similar to glucan 1,6-alpha-glucosidase [Streptococcus pyogenes MGAS10394]; glucan 1,6-alpha-glucosidase 213664..215283 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111498 YP_002995968.1 CDS SDEG_0237 NC_012891.1 215449 219072 D similar to pullulanase [Streptococcus pyogenes MGAS10394]; pullulanase 215449..219072 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111499 YP_002995969.1 CDS SDEG_0238 NC_012891.1 219225 219515 R similar to hypothetical protein SPCG 1675 [Streptococcus pneumoniae CGSP14]; hypothetical protein complement(219225..219515) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111500 YP_002995970.1 CDS SDEG_0239 NC_012891.1 219671 220021 D similar to thioredoxin [Streptococcus pyogenes MGAS2096]; thioredoxin 219671..220021 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111501 YP_002995971.1 CDS yajC NC_012891.1 220128 220487 D member of preprotein translocase; forms a heterotrimer with SecD and SecF; links the SecD/SecF/YajC/YidC complex with the SecY/SecE/SecG complex; preprotein translocase subunit YajC 220128..220487 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111502 YP_002995972.1 CDS SDEG_0241 NC_012891.1 220715 221464 D catalyzes the formation of undecaprenyl pyrophosphate from isopentenyl pyrophosphate; UDP pyrophosphate synthase 220715..221464 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111958 YP_002995973.1 CDS SDEG_0242 NC_012891.1 221477 222271 D similar to phosphatidate cytidylyltransferase [Streptococcus pyogenes MGAS10394]; phosphatidate cytidylyltransferase 221477..222271 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111503 YP_002995974.1 CDS SDEG_0243 NC_012891.1 222369 223082 D similar to pheromone-processing membrane metalloprotease [Streptococcus pyogenes MGAS10394]; pheromone-processing membrane metalloprotease 222369..223082 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111504 YP_002995975.1 CDS SDEG_0244 NC_012891.1 222956 223627 D similar to pheromone-processing membrane metalloprotease [Streptococcus pyogenes MGAS10394]; pheromone-processing membrane metalloprotease 222956..223627 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111505 YP_002995976.1 CDS SDEG_0245 NC_012891.1 223818 225674 D catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro); prolyl-tRNA synthetase 223818..225674 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111506 YP_002995977.1 CDS SDEG_0246 NC_012891.1 225727 226284 D similar to hypothetical protein ProS [Streptococcus equi subsp. zooepidemicus MGCS10565]; hypothetical protein 225727..226284 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111507 YP_002995978.1 CDS polC NC_012891.1 226401 230798 D catalyzes DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time; required for leading strand synthesis; PolC exhibits 3' to 5' exonuclease activity; DNA polymerase III PolC 226401..230798 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111508 YP_002995979.1 CDS SDEG_0248 NC_012891.1 230964 231392 D similar to MarR family transcriptional regulator [Streptococcus pyogenes M1 GAS]; MarR family transcriptional regulator 230964..231392 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111509 YP_002995980.1 CDS SDEG_0249 NC_012891.1 231478 232029 D similar to NADPH-dependent FMN reductase [Streptococcus sanguinis SK36]; NADPH-dependent FMN reductase 231478..232029 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111510 YP_002995981.1 CDS def NC_012891.1 232097 232711 R cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+); peptide deformylase complement(232097..232711) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111511 YP_002995982.1 CDS SDEG_0251 NC_012891.1 233011 233676 R similar to Crp-like transcriptional regulator [Streptococcus thermophilus LMD-9]; Crp-like transcriptional regulator complement(233011..233676) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111666 YP_002995983.1 CDS SDEG_0252 NC_012891.1 233764 234948 D similar to hypothetical protein SMU.145 [Streptococcus mutans UA159]; hypothetical protein 233764..234948 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111512 YP_002995984.1 CDS rpsO NC_012891.1 235096 235365 D primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence; 30S ribosomal protein S15 235096..235365 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111513 YP_002995985.1 CDS SDEG_0254 NC_012891.1 235349 235480 D similar to hypothetical protein M6 Spy1673 [Streptococcus pyogenes MGAS10394]; hypothetical protein 235349..235480 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111107 YP_002995986.1 CDS SDEG_0255 NC_012891.1 235616 237778 D similar to PTS system mannitol (Cryptic)-specific IIA component [Streptococcus pyogenes MGAS10394]; PTS system mannitol (cryptic)-specific transporter subunit IIA 235616..237778 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111514 YP_002995987.1 CDS SDEG_0256 NC_012891.1 237750 238055 D similar to PTS system IIB component [Streptococcus pyogenes MGAS6180]; PTS system transporter subunit IIB 237750..238055 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111515 YP_002995988.1 CDS ulaA NC_012891.1 238082 239461 D membrane component; functions with enzymes IIB (sgaB; ulaB) and IIA (sgaA; ulaC) enzyme I and HPr for anaerobic utilization and uptake of L-ascorbate; sgaTBA are regulated by yifQ as well as Crp and Fnr; PTS system ascorbate-specific transporter subunit IIC 238082..239461 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111354 YP_002995989.1 CDS SDEG_0258 NC_012891.1 239471 240202 D similar to novel fructose-6-phosphate aldolase from Escherichia coli; enzyme from Methanocaldococcus janaschii shows transaldolase activity; translaldolase 239471..240202 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111939 YP_002995990.1 CDS SDEG_0259 NC_012891.1 240482 242626 D similar to Polyribonucleotide nucleotidyltransferase [Streptococcus pyogenes MGAS10394]; polynucleotide phosphorylase/polyadenylase 240482..242626 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111355 YP_002995991.1 CDS SDEG_0260 NC_012891.1 242619 243371 D similar to hypothetical protein M6 Spy1667 [Streptococcus pyogenes MGAS10394]; hypothetical protein 242619..243371 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111356 YP_002995992.1 CDS SDEG_0261 NC_012891.1 243380 243964 D similar to serine acetyltransferase [Streptococcus pyogenes MGAS10394]; serine acetyltransferase 243380..243964 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111357 YP_002995993.1 CDS SDEG_0262 NC_012891.1 244215 244445 D similar to hypothetical protein M5005 Spy 1656 [Streptococcus pyogenes MGAS5005]; hypothetical protein 244215..244445 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111358 YP_002995994.1 CDS cysS NC_012891.1 244473 245816 D catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA; cysteinyl-tRNA synthetase 244473..245816 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111359 YP_002995995.1 CDS SDEG_0264 NC_012891.1 245809 246210 D similar to hypothetical protein SpyM51627 [Streptococcus pyogenes str. Manfredo]; hypothetical protein 245809..246210 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111658 YP_002995996.1 CDS SDEG_0265 NC_012891.1 246327 246653 D similar to conserved hypothetical protein [Enterococcus faecium DO]; hypothetical protein 246327..246653 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111360 YP_002995997.1 CDS SDEG_0266 NC_012891.1 246845 247357 D similar to hypothetical protein EF3281 [Enterococcus faecalis V583]; hypothetical protein 246845..247357 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111361 YP_002995998.1 CDS SDEG_0267 NC_012891.1 247768 248493 D similar to hypothetical membrane associated protein [Streptococcus pyogenes MGAS2096]; hypothetical protein 247768..248493 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111362 YP_002995999.1 CDS SDEG_0268 NC_012891.1 248600 249346 D similar to 23S rRNA Gm2251 methyltransferase [Streptococcus pyogenes MGAS10394]; 23S rRNA Gm2251-methyltransferase 248600..249346 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111363 YP_002996000.1 CDS SDEG_0269 NC_012891.1 249350 249868 D similar to hypothetical protein SpyM51624 [Streptococcus pyogenes str. Manfredo]; hypothetical protein 249350..249868 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111364 YP_002996001.1 CDS SDEG_0270 NC_012891.1 249952 250827 D similar to DegV family protein [Streptococcus pyogenes MGAS10394]; DegV family protein 249952..250827 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111365 YP_002996002.1 CDS SDEG_0271 NC_012891.1 250962 251660 D similar to hypothetical membrane spanning protein [Streptococcus pyogenes MGAS10394]; hypothetical protein 250962..251660 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111366 YP_002996003.1 CDS SDEG_0272 NC_012891.1 251657 251863 D similar to Cro/CI family transcriptional regulator [Streptococcus pyogenes MGAS6180]; Cro/CI family transcriptional regulator 251657..251863 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111367 YP_002996004.1 CDS SDEG_0273 NC_012891.1 251995 252114 D similar to transposase [Streptococcus pyogenes MGAS10394]; transposase 251995..252114 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111368 YP_002996005.1 CDS SDEG_0274 NC_012891.1 252188 252280 D similar to transposase [Streptococcus pyogenes MGAS5005]; transposase 252188..252280 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111369 YP_002996006.1 CDS SDEG_0275 NC_012891.1 252277 252507 D similar to transposase [Streptococcus pyogenes MGAS10750]; transposase 252277..252507 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111370 YP_002996007.1 CDS SDEG_0276 NC_012891.1 252596 253021 D similar to transposase [Streptococcus pyogenes MGAS10270]; transposase 252596..253021 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111371 YP_002996008.1 CDS rplM NC_012891.1 253152 253703 D in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit; 50S ribosomal protein L13 253152..253703 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111372 YP_002996009.1 CDS rpsI NC_012891.1 253724 254116 D forms a direct contact with the tRNA during translation; 30S ribosomal protein S9 253724..254116 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111373 YP_002996010.1 CDS SDEG_0279 NC_012891.1 254244 255398 R similar to phage integrase family site specific recombinase [Streptococcus agalactiae A909]; site-specific recombinase, phage integrase family complement(254244..255398) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111100 YP_002996011.1 CDS SDEG_0280 NC_012891.1 255462 256052 R similar to transcriptional regulator Cro/CI family [Streptococcus agalactiae CJB111]; Cro/CI family transcriptional regulator complement(255462..256052) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111374 YP_002996012.1 CDS SDEG_0281 NC_012891.1 256207 256512 D similar to hypothetical protein SAG0219 [Streptococcus agalactiae 2603V/R]; hypothetical protein 256207..256512 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111375 YP_002996013.1 CDS SDEG_0282 NC_012891.1 256649 256927 D similar to hypothetical protein SAG0220 [Streptococcus agalactiae 2603V/R]; hypothetical protein 256649..256927 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111376 YP_002996014.1 CDS SDEG_0283 NC_012891.1 256938 257168 D similar to hypothetical protein SAG0221 [Streptococcus agalactiae 2603V/R]; hypothetical protein 256938..257168 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111377 YP_002996015.1 CDS SDEG_0284 NC_012891.1 257181 257507 D similar to hypothetical protein SAG0222 [Streptococcus agalactiae 2603V/R]; hypothetical protein 257181..257507 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111378 YP_002996016.1 CDS SDEG_0285 NC_012891.1 257511 258140 D similar to conserved hypothetical protein [Streptococcus agalactiae CJB111]; hypothetical protein 257511..258140 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111379 YP_002996017.1 CDS SDEG_0287 NC_012891.1 259365 259799 D similar to hypothetical protein SAG0225 [Streptococcus agalactiae 2603V/R]; hypothetical protein 259365..259799 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111381 YP_002996018.1 CDS SDEG_0288 NC_012891.1 260115 261371 D similar to recombination protein [Streptococcus agalactiae 2603V/R]; recombination protein 260115..261371 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111382 YP_002996019.1 CDS SDEG_0289 NC_012891.1 261539 262009 D similar to hypothetical protein SAG0227 [Streptococcus agalactiae 2603V/R]; hypothetical protein 261539..262009 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111383 YP_002996020.1 CDS SDEG_0290 NC_012891.1 262314 262649 R similar to hypothetical protein SAG0228 [Streptococcus agalactiae 2603V/R]; hypothetical protein complement(262314..262649) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111384 YP_002996021.1 CDS SDEG_0291 NC_012891.1 262639 262926 R similar to hypothetical protein SAG0229 [Streptococcus agalactiae 2603V/R]; hypothetical protein complement(262639..262926) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111385 YP_002996022.1 CDS int NC_012891.1 263330 264040 R similar to phage integrase family integrase/recombinase [Streptococcus thermophilus LMG 18311]; integrase/recombinase, phage integrase family complement(263330..264040) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111386 YP_002996023.1 CDS SDEG_0293 NC_012891.1 264073 264459 R similar to transposase [Streptococcus pyogenes MGAS9429]; transposase complement(264073..264459) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110868 YP_002996024.1 CDS SDEG_0294 NC_012891.1 264511 264933 R similar to transposase [Streptococcus pyogenes MGAS2096]; transposase complement(264511..264933) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111387 YP_002996025.1 CDS labC NC_012891.1 265043 266161 D similar to lantibiotic biosynthesis protein [Streptococcus thermophilus LMG 18311]; lantibiotic biosynthesis protein 265043..266161 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111388 YP_002996026.1 CDS labT NC_012891.1 266191 267456 D similar to lantibiotic efflux protein [Streptococcus thermophilus CNRZ1066]; lantibiotic efflux protein 266191..267456 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110880 YP_002996027.1 CDS SDEG_0297 NC_012891.1 267515 267952 D similar to ATP-dependent DNA helicase recG [Streptococcus agalactiae 515]; ATP-dependent DNA helicase 267515..267952 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110881 YP_002996028.1 CDS SDEG_0298 NC_012891.1 268034 268201 D similar to predicted transcriptional regulator containing HTH domain [Streptococcus thermophilus LMD-9]; transcriptional regulator containing HTH domain 268034..268201 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111389 YP_002996029.1 CDS SDEG_0299 NC_012891.1 268695 269963 R similar to 5-methylcytosine methyltransferase [Lactococcus lactis subsp. lactis bv. diacetylactis]; 5-methylcytosine methyltransferase complement(268695..269963) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111390 YP_002996030.1 CDS SDEG_0300 NC_012891.1 270078 271568 D similar to restriction enzyme [Lactococcus lactis subsp. lactis bv. diacetylactis]; restriction enzyme 270078..271568 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111391 YP_002996031.1 CDS SDEG_0301 NC_012891.1 271580 271930 D no hit; hypothetical protein 271580..271930 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111392 YP_002996032.1 CDS SDEG_0303 NC_012891.1 273732 274301 D no hit; hypothetical protein 273732..274301 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111394 YP_002996033.1 CDS SDEG_0304 NC_012891.1 275079 277028 D similar to hypothetical protein CLOSS21 00385 [Clostridium sp. SS2/1]; hypothetical protein 275079..277028 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111395 YP_002996034.1 CDS SDEG_0305 NC_012891.1 277030 277488 D similar to PTS system galactitol-specific IIA component [Streptococcus agalactiae A909]; PTS system galactitol-specific transporter subunit IIA 277030..277488 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111396 YP_002996035.1 CDS SDEG_0306 NC_012891.1 277498 278838 D similar to PTS system galactitol-specific IIC component [Streptococcus agalactiae A909]; PTS system galactitol-specific transporter subunit IIC 277498..278838 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111397 YP_002996036.1 CDS SDEG_0307 NC_012891.1 278835 279119 D similar to PTS system galactitol-specific IIB component [Streptococcus agalactiae A909]; PTS system galactitol-specific transporter subunit IIB 278835..279119 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111398 YP_002996037.1 CDS SDEG_0308 NC_012891.1 279121 279960 D similar to hypothetical protein ANACAC 03037 [anaerostipes caccae DSM 14662]; hypothetical protein 279121..279960 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111399 YP_002996038.1 CDS SDEG_0309 NC_012891.1 279960 280637 D similar to hypothetical protein ANACAC 03039 [anaerostipes caccae DSM 14662]; hypothetical protein 279960..280637 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111400 YP_002996039.1 CDS SDEG_0310 NC_012891.1 280649 281170 D similar to hypothetical protein ANACAC 03038 [anaerostipes caccae DSM 14662]; hypothetical protein 280649..281170 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111401 YP_002996040.1 CDS SDEG_0311 NC_012891.1 281418 282233 D similar to hypothetical protein CLOL250 01537 [Clostridium sp. L2-50]; hypothetical protein 281418..282233 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111402 YP_002996041.1 CDS comX.2 NC_012891.1 287809 288291 D similar to competence protein ComX1 [Streptococcus pyogenes MGAS315]; competence protein ComX1 287809..288291 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111409 YP_002996042.1 CDS SDEG_0319 NC_012891.1 288523 289872 R catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP; lysine and threonine sensitive; aspartate kinase complement(288523..289872) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111637 YP_002996043.1 CDS truA NC_012891.1 290018 290767 D mediates pseudouridylation (positions 38, 39, 40) at the tRNA anticodon region which contributes to the structural stability; tRNA pseudouridine synthase A 290018..290767 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111410 YP_002996044.1 CDS SDEG_0321 NC_012891.1 290757 291524 D catalyzes the formation of 4-amino-2-methyl-5-diphosphomethylpyrimidine; phosphomethylpyrimidine kinase 290757..291524 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111930 YP_002996045.1 CDS SDEG_0322 NC_012891.1 291508 291984 D similar to hypothetical membrane spanning protein [Streptococcus pyogenes MGAS5005]; hypothetical protein 291508..291984 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111411 YP_002996046.1 CDS SDEG_0323 NC_012891.1 291995 292558 D similar to hypothetical protein M28 Spy1603 [Streptococcus pyogenes MGAS6180]; hypothetical protein 291995..292558 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111412 YP_002996047.1 CDS SDEG_0324 NC_012891.1 292621 293466 R similar to conserved hypothetical protein possible mechanosensitive ion channel [Streptococcuspyogenes NZ131]; potassium efflux system/small-conductance mechanosensitive channel complement(292621..293466) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111413 YP_002996048.1 CDS amyE NC_012891.1 293860 295263 D similar to alpha-amylase precursor AmyE [Streptococcus equi subsp. zooepidemicus MGCS10565]; alpha-amylase 293860..295263 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111414 YP_002996049.1 CDS amyE NC_012891.1 295486 296892 D similar to alpha-amylase precursor AmyE [Streptococcus equi subsp. zooepidemicus MGCS10565]; alpha-amylase 295486..296892 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112324 YP_002996050.1 CDS tig NC_012891.1 297013 298383 D Tig; RopA; peptidyl-prolyl cis/trans isomerase; promotes folding of newly synthesized proteins; binds ribosomal 50S subunit; forms a homodimer; trigger factor 297013..298383 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112325 YP_002996051.1 CDS SDEG_0328 NC_012891.1 298597 299175 D participates in both the initiation and recycling phases of transcription; in the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling; DNA-directed RNA polymerase subunit delta 298597..299175 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111055 YP_002996052.1 CDS pyrG NC_012891.1 299458 301062 D CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer; CTP synthetase 299458..301062 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111415 YP_002996053.1 CDS lytS NC_012891.1 301138 302898 D similar to autolysin sensor kinase protein [Staphylococcus aureus subsp. aureus MRSA252]; autolysin sensor kinase protein 301138..302898 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111343 YP_002996054.1 CDS lytR NC_012891.1 302895 303623 D similar to two-component response regulator LytR [Carnobacterium sp. AT7]; two-component response regulator 302895..303623 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110915 YP_002996055.1 CDS lrgA NC_012891.1 303719 304204 D similar to murein hydrolase regulator LrgA [Staphylococcus aureus subsp. aureus JH9]; murein hydrolase regulator 303719..304204 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110914 YP_002996056.1 CDS lrgB NC_012891.1 304222 304929 D in conjunction with LrgA this protein inhibits the expression or activity of extracellular murein hydrolases; antiholin-like protein LrgB 304222..304929 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110909 YP_002996057.1 CDS SDEG_0334 NC_012891.1 305089 306015 D similar to alpha /beta hydrolase [Streptococcus pyogenes MGAS10394]; alpha/beta hydrolase 305089..306015 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110910 YP_002996058.1 CDS SDEG_0336 NC_012891.1 306360 307241 D catalyzes the formation of glycerone phosphate and glyceraldehyde 3-phosphate from fructose 1,6, bisphosphate; fructose-bisphosphate aldolase 306360..307241 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111417 YP_002996059.1 CDS SDEG_0337 NC_012891.1 307765 308049 D similar to transposase [Streptococcus pyogenes MGAS315]; transposase 307765..308049 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111418 YP_002996060.1 CDS SDEG_0338 NC_012891.1 308046 308792 D similar to transposase [Streptococcus pyogenes MGAS10270]; transposase 308046..308792 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111419 YP_002996061.1 CDS rpmB NC_012891.1 308963 309151 D required for 70S ribosome assembly; 50S ribosomal protein L28 308963..309151 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111420 YP_002996062.1 CDS SDEG_0340 NC_012891.1 309305 309670 D similar to alkaline-shock protein [Streptococcus pyogenes M1 GAS]; alkaline-shock protein 309305..309670 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111080 YP_002996063.1 CDS SDEG_0341 NC_012891.1 309670 311334 D similar to hypothetical protein spyM18 1950 [Streptococcus pyogenes MGAS8232]; hypothetical protein 309670..311334 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111421 YP_002996064.1 CDS SDEG_0342 NC_012891.1 311570 312460 D similar to membrane protease protein family [Streptococcus pyogenes MGAS10394]; membrane protease protein family 311570..312460 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111422 YP_002996065.1 CDS SDEG_0343 NC_012891.1 312856 313665 R similar to amino acid transport ATP-binding protein [Streptococcus pyogenes MGAS10394]; amino acid ABC transporter ATP-binding protein complement(312856..313665) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111423 YP_002996066.1 CDS SDEG_0344 NC_012891.1 313589 315175 R similar to ABC transporter amino acid-binding protein [Streptococcus pyogenes MGAS10394]; amino acid ABC transporter substrate-binding protein complement(313589..315175) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111424 YP_002996067.1 CDS SDEG_0345 NC_012891.1 315356 317281 D similar to hypothetical membrane spanning protein [Streptococcus pyogenes MGAS2096]; hypothetical protein 315356..317281 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111425 YP_002996068.1 CDS bacA NC_012891.1 317347 318186 D BacA; phosphatase activity in Escherichia coli not kinase; involved in bacitracin resistance as bacitracin supposedly sequesters undecaprenyl disphosphate which reduces the pool of lipid carrier available to the cell; UDP pyrophosphate phosphatase 317347..318186 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111426 YP_002996069.1 CDS mecA NC_012891.1 318324 319091 D enables recognition and targeting of proteins for proteolysis, involved in negative regulation of competence; adaptor protein 318324..319091 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112365 YP_002996070.1 CDS SDEG_0348 NC_012891.1 319098 320267 D similar to undecaprenyl-phosphate alpha-N-acetylglucosaminephosphotransferase [Streptococcus pyogenes MGAS10750]; UDP-phosphate-alpha-N- acetylglucosaminyltransferase 319098..320267 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110934 YP_002996071.1 CDS sufC NC_012891.1 320380 321150 D similar to ATP-dependent transporter sufC [Streptococcus pyogenes MGAS2096]; ATP-dependent transporter 320380..321150 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111427 YP_002996072.1 CDS sufD NC_012891.1 321246 322508 D similar to SufD protein [Streptococcus pyogenes MGAS10270]; iron-sulfur cluster assembly protein 321246..322508 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110508 YP_002996073.1 CDS sufS NC_012891.1 322539 323765 D similar to aminotransferase [Streptococcus pyogenes MGAS315]; aminotransferase 322539..323765 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110509 YP_002996074.1 CDS iscU NC_012891.1 323752 324228 D similar to IscU [Streptococcus pyogenes MGAS10394]; iron-sulfur cluster assembly scaffold protein 323752..324228 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110510 YP_002996075.1 CDS SDEG_0353 NC_012891.1 324221 325639 D similar to hypothetical protein spyM18 0278 [Streptococcus pyogenes MGAS8232]; hypothetical protein 324221..325639 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110872 YP_002996076.1 CDS SDEG_0354 NC_012891.1 325815 326996 R similar to D-alanyl-D-alanine carboxypeptidase [Streptococcus pyogenes MGAS10270]; D-alanyl-D-alanine carboxypeptidase complement(325815..326996) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111428 YP_002996077.1 CDS dacA NC_012891.1 327140 328378 R similar to D-alanyl-D-alanine carboxypeptidase [Streptococcus pyogenes MGAS315]; D-alanyl-D-alanine carboxypeptidase complement(327140..328378) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111429 YP_002996078.1 CDS oppA NC_012891.1 328700 330679 D similar to oligopeptide-binding protein [Streptococcus pyogenes MGAS6180]; oligopeptide-binding protein 328700..330679 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111660 YP_002996079.1 CDS oppB NC_012891.1 330733 332247 D similar to oligopeptide transport system permease protein oppB [Streptococcus pyogenes MGAS10750]; oligopeptide transport system permease 330733..332247 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111733 YP_002996080.1 CDS oppC NC_012891.1 332247 333173 D similar to oligopeptide permease [Streptococcus pyogenes MGAS8232]; oligopeptide permease 332247..333173 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111735 YP_002996081.1 CDS oppD NC_012891.1 333182 334252 D similar to oligopeptide transport ATP-binding protein [Streptococcus pyogenes MGAS6180]; oligopeptide transport ATP-binding protein 333182..334252 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111737 YP_002996082.1 CDS oppF NC_012891.1 334245 335168 D similar to oligopeptide ABC transporter, ATP-binding protein [Streptococcus pyogenes MGAS315]; oligopeptide ABC transporter ATP-binding protein 334245..335168 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111739 YP_002996083.1 CDS SDEG_0367 NC_012891.1 343571 344155 D similar to lipase [Streptococcus pyogenes MGAS10394]; lipase 343571..344155 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112055 YP_002996084.1 CDS SDEG_0368 NC_012891.1 344155 345273 D in Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis; GTP-binding protein YqeH 344155..345273 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112056 YP_002996085.1 CDS SDEG_0369 NC_012891.1 345218 345607 D similar to hypothetical RNA binding protein [Streptococcus pyogenes MGAS10394]; RNA binding protein 345218..345607 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112057 YP_002996086.1 CDS nadD NC_012891.1 345676 346308 D transfers an adenyl group from ATP to NaMN to form nicotinic acid adenine dinucleotide (NaAD) which is then converted to the ubiquitous compound NAD by NAD synthetase; essential enzyme in bacteria; nicotinic acid mononucleotide adenylyltransferase 345676..346308 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112058 YP_002996087.1 CDS SDEG_0371 NC_012891.1 346305 346898 D similar to hydrolase (HAD superfamily) [Streptococcus pyogenes MGAS10394]; HAD superfamily hydrolase 346305..346898 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111704 YP_002996088.1 CDS SDEG_0372 NC_012891.1 346874 347134 D similar to isochorismatase [Streptococcus pyogenes MGAS10750]; isochorismatase 346874..347134 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112059 YP_002996089.1 CDS SDEG_0373 NC_012891.1 347124 347489 D similar to iojap protein family [Streptococcus pyogenes MGAS10394]; iojap protein family 347124..347489 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112060 YP_002996090.1 CDS SDEG_0374 NC_012891.1 347525 348280 D similar to methyltransferase [Streptococcus pyogenes MGAS10394]; methyltransferase 347525..348280 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112061 YP_002996091.1 CDS SDEG_0375 NC_012891.1 348355 349452 D similar to hypothetical protein stu1615 [Streptococcus thermophilus LMG 18311]; hypothetical protein 348355..349452 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112062 YP_002996092.1 CDS SDEG_0376 NC_012891.1 349555 350268 D similar to transcriptional regulator MerR family [Streptococcus equi subsp. zooepidemicus MGCS10565]; MerR family transcriptional regulator 349555..350268 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112063 YP_002996093.1 CDS SDEG_0377 NC_012891.1 350879 352300 D similar to internalin A-like histidine triad lipoprotein [Streptococcus equi subsp. zooepidemicus MGCS10565]; internalin A-like histidine triad lipoprotein 350879..352300 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112064 YP_002996094.1 CDS SDEG_0378 NC_012891.1 352353 353300 D no hit; hypothetical protein 352353..353300 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112065 YP_002996095.1 CDS bioB NC_012891.1 353464 354390 D similar to biotin synthetase [Streptococcus agalactiae 2603V/R]; biotin synthetase 353464..354390 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112066 YP_002996096.1 CDS SDEG_0380 NC_012891.1 354559 355275 D similar to hypothetical protein M6 Spy0297 [Streptococcus pyogenes MGAS10394]; hypothetical protein 354559..355275 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112375 YP_002996097.1 CDS SDEG_0381 NC_012891.1 355483 356325 D similar to ABC transporter substrate-binding protein [Streptococcus pyogenes MGAS10394]; ABC transporter substrate-binding protein 355483..356325 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112067 YP_002996098.1 CDS SDEG_0382 NC_012891.1 356480 357334 D similar to ABC transporter substrate-binding protein [Streptococcus pyogenes MGAS10394]; ABC transporter substrate-binding protein 356480..357334 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112068 YP_002996099.1 CDS SDEG_0383 NC_012891.1 357512 358357 D similar to ABC transporter substrate-binding protein [Streptococcus pyogenes MGAS10394]; ABC transporter substrate-binding protein 357512..358357 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112069 YP_002996100.1 CDS dapE NC_012891.1 358432 359805 D similar to acetylornithine deacetylase /succinyl-diaminopimelate desuccinylase (M20/M25/M40 family peptidase), [Streptococcus sanguinis SK36]; acetylornithine deacetylase 358432..359805 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112070 YP_002996101.1 CDS SDEG_0385 NC_012891.1 359798 360862 D similar to ABC transporter ATP-binding protein [Streptococcus pyogenes MGAS10394]; ABC transporter ATP-binding protein 359798..360862 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111661 YP_002996102.1 CDS SDEG_0386 NC_012891.1 360863 361555 D similar to ABC transporter permease protein [Streptococcus pyogenes MGAS10394]; ABC transporter permease 360863..361555 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112071 YP_002996103.1 CDS SDEG_0387 NC_012891.1 361609 362979 R similar to Branched-chain amino acid transport system carrier protein [Streptococcus pyogenes MGAS10394]; branched-chain amino acid transport system carrier protein complement(361609..362979) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112072 YP_002996104.1 CDS SDEG_0388 NC_012891.1 363220 364434 D involved in the import of serine and threonine coupled with the import of sodium; serine/threonine transporter SstT 363220..364434 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112073 YP_002996105.1 CDS ktrA NC_012891.1 364492 365166 R similar to KtrA [Streptococcus pyogenes MGAS10394]; potassium uptake protein complement(364492..365166) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112074 YP_002996106.1 CDS ktrB NC_012891.1 365176 366552 R similar to KtrB [Streptococcus pyogenes MGAS10394]; potassium uptake protein complement(365176..366552) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110878 YP_002996107.1 CDS gidB NC_012891.1 366636 367349 R glucose-inhibited division protein B; SAM-dependent methyltransferase; methylates the N7 position of guanosine in position 527 of 16S rRNA; 16S rRNA methyltransferase GidB complement(366636..367349) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110879 YP_002996108.1 CDS lemA NC_012891.1 367502 368059 D similar to LemA [Streptococcus pyogenes MGAS10394]; cytoplasmic membrane protein 367502..368059 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111993 YP_002996109.1 CDS SDEG_0393 NC_012891.1 368106 368999 D metalloprotease; heat shock protein HtpX 368106..368999 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110891 YP_002996110.1 CDS SDEG_0394 NC_012891.1 369263 369799 D similar to hypothetical cytosolic protein [Streptococcus pyogenes MGAS10394]; hypothetical protein 369263..369799 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112075 YP_002996111.1 CDS covR NC_012891.1 370069 370755 D similar to response regulator CsrR [Streptococcus pyogenes MGAS10394]; response regulator 370069..370755 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112076 YP_002996112.1 CDS covS NC_012891.1 370761 372260 D similar to transmembrane histidine kinase CsrS [Streptococcus pyogenes MGAS10394]; transmembrane histidine kinase 370761..372260 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111643 YP_002996113.1 CDS nrdR NC_012891.1 372466 372960 D similar to ribonucleotide reductase NrdR family transcriptional regulator [Streptococcus equi subsp. zooepidemicus MGCS10565]; NrdR family transcriptional regulator 372466..372960 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111644 YP_002996114.1 CDS dnaB NC_012891.1 372944 374122 D replication initiation/membrane attachment protein[DNA replication recombination and repair]; COG3611; similar to replicative DNA helicase [Streptococcus pyogenes MGAS6180]; replicative DNA helicase 372944..374122 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111723 YP_002996115.1 CDS dnaI NC_012891.1 374123 375025 D Primosomal protein that may act to load helicase DnaC during DNA replication; primosomal protein DnaI 374123..375025 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111843 YP_002996116.1 CDS engA NC_012891.1 375088 376398 D EngA; essential Neisserial GTPase; synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains; GTP-binding protein EngA 375088..376398 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111847 YP_002996117.1 CDS snf NC_012891.1 376615 379713 D similar to SWF/SNF family helicase [Streptococcus pyogenes MGAS10394]; SWF/SNF family helicase 376615..379713 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111870 YP_002996118.1 CDS SDEG_0402 NC_012891.1 379954 380559 D similar to hypothetical protein spyM18 0396 [Streptococcus pyogenes MGAS8232]; hypothetical protein 379954..380559 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110493 YP_002996119.1 CDS murC NC_012891.1 380603 381934 D Catalyzes the formation of UDP-N-acetylmuramoyl-L-alanine from UDP-N-acetylmuramate and L-alanine in peptidoglycan synthesis; UDP-N-acetylmuramate--L-alanine ligase 380603..381934 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112077 YP_002996120.1 CDS SDEG_0404 NC_012891.1 381978 382463 D similar to arylalkylamine n-acetyltransferase [Streptococcus pyogenes MGAS8232]; arylalkylamine n-acetyltransferase 381978..382463 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111684 YP_002996121.1 CDS SDEG_0405 NC_012891.1 382575 384182 D similar to aminodeoxychorismate lyase family [Streptococcus pyogenes MGAS10394]; aminodeoxychorismate lyase family 382575..384182 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112078 YP_002996122.1 CDS greA NC_012891.1 384255 384737 D necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus; transcription elongation factor GreA 384255..384737 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112079 YP_002996123.1 CDS SDEG_0407 NC_012891.1 384947 385870 R involved in biogenesis of membrane proteins; Firmicutes specific proteins are shorter than other bacterial counterparts and have a signal peptide and lipid attachment site; OxaA-like protein complement(384947..385870) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112018 YP_002996124.1 CDS SDEG_0408 NC_012891.1 385953 386264 R catalyzes the hydrolysis of acylphosphate; acylphosphatase complement(385953..386264) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112080 YP_002996125.1 CDS SDEG_0409 NC_012891.1 386494 387231 D similar to 23S rRNA methyltransferase [Streptococcus pyogenes MGAS10394]; 23S rRNA methyltransferase 386494..387231 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112081 YP_002996126.1 CDS SDEG_0410 NC_012891.1 387270 387770 D similar to hydrolase (HAD superfamily) [Streptococcus pyogenes MGAS10394]; HAD superfamily hydrolase 387270..387770 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112082 YP_002996127.1 CDS SDEG_0411 NC_012891.1 387785 388474 D similar to integral membrane protein [Streptococcus pyogenes MGAS10394]; integral membrane protein 387785..388474 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112083 YP_002996128.1 CDS SDEG_0412 NC_012891.1 389002 389244 D similar to hypothetical protein M6 Spy0328 [Streptococcus pyogenes MGAS10394]; hypothetical protein 389002..389244 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112084 YP_002996129.1 CDS glr NC_012891.1 389421 390218 D converts L-glutamate to D-glutamate, a component of peptidoglycan; glutamate racemase 389421..390218 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112085 YP_002996130.1 CDS SDEG_0414 NC_012891.1 390176 391201 D HAM1-like protein; Rec-dependent growth; RgdB; yggV; it is suspected that this protein functions to remove misincorporated bases such as xanthine or hypoxanthine; deoxyribonucleotide triphosphate pyrophosphatase/hypothetical protein 390176..391201 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112010 YP_002996131.1 CDS SDEG_0415 NC_012891.1 391180 391701 D similar to hypothetical protein spyM18 0413 [Streptococcus pyogenes MGAS8232]; hypothetical protein 391180..391701 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112086 YP_002996132.1 CDS SDEG_0416 NC_012891.1 391698 392159 D similar to hypothetical protein [Streptococcus pyogenes MGAS5005]; hypothetical protein 391698..392159 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112087 YP_002996133.1 CDS xerD NC_012891.1 392156 392902 D site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs; site-specific tyrosine recombinase XerD 392156..392902 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112088 YP_002996134.1 CDS scpA NC_012891.1 392902 393609 D functions during chromosome segregation; may form a condensin-like structure with SMC and ScpB; segregation and condensation protein A 392902..393609 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112089 YP_002996135.1 CDS scpB NC_012891.1 393606 394169 D functions during chromosome segregation; may form a condensin-like structure with SMC and ScpA; forms a homodimer; segregation and condensation protein B 393606..394169 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110466 YP_002996136.1 CDS SDEG_0420 NC_012891.1 394278 395000 D similar to Ribosomal large subunit pseudouridine synthase B [Streptococcus pyogenes MGAS10394]; ribosomal large subunit pseudouridine synthase B 394278..395000 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110467 YP_002996137.1 CDS SDEG_0421 NC_012891.1 394997 395248 D similar to hypothetical protein Sez 1639 [Streptococcus equi subsp. zooepidemicus MGCS10565]; hypothetical protein 394997..395248 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112090 YP_002996138.1 CDS SDEG_0422 NC_012891.1 395389 395985 D similar to 23S rRNA methyltransferase [Streptococcus pyogenes MGAS10394]; tRNA (cytosine34-2'-O-)-methyltransferase 395389..395985 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112091 YP_002996139.1 CDS SDEG_0423 NC_012891.1 396540 397103 D similar to hypothetical protein spyM18 0427 [Streptococcus pyogenes MGAS8232]; hypothetical protein 396540..397103 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112092 YP_002996140.1 CDS SDEG_0424 NC_012891.1 397108 397758 D similar to phosphatidylglycerophosphatase B homolog [Streptococcus pyogenes MGAS5005]; phosphatidylglycerophosphatase B 397108..397758 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112093 YP_002996141.1 CDS SDEG_0425 NC_012891.1 397935 398876 D similar to Fe-S oxidoreductase [Streptococcus pyogenes MGAS10394]; Fe-S oxidoreductase 397935..398876 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112094 YP_002996142.1 CDS SDEG_0426 NC_012891.1 398899 399453 D similar to SAM-dependent methyltransferase [Streptococcus pyogenes M1 GAS]; SAM-dependent methyltransferase 398899..399453 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112095 YP_002996143.1 CDS SDEG_0427 NC_012891.1 399573 400907 D similar to hemolysin [Streptococcus pyogenes MGAS8232]; hemolysin 399573..400907 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112096 YP_002996144.1 CDS SDEG_0428 NC_012891.1 400913 401776 D similar to pyruvate formate-lyase activating enzyme [Streptococcus pyogenes MGAS10394]; pyruvate formate-lyase activating enzyme 400913..401776 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112097 YP_002996145.1 CDS SDEG_0429 NC_012891.1 401906 402841 D catalyzes the hydrolysis of pyrophosphate to phosphate; manganese-dependent inorganic pyrophosphatase 401906..402841 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112098 YP_002996146.1 CDS SDEG_0430 NC_012891.1 402841 403569 D similar to hypothetical cytosolic protein [Streptococcus pyogenes MGAS10394]; hypothetical protein 402841..403569 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112099 YP_002996147.1 CDS fhuG NC_012891.1 403614 404615 R similar to ferrichrome transport system permease protein [Streptococcus pyogenes MGAS5005]; ferrichrome transport system permease complement(403614..404615) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112100 YP_002996148.1 CDS fhuB NC_012891.1 404612 405655 R similar to ferrichrome transport system permease protein [Streptococcus pyogenes MGAS5005]; ferrichrome transport system permease complement(404612..405655) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111897 YP_002996149.1 CDS fhuD NC_012891.1 405648 406586 R similar to ferrichrome-binding protein [Streptococcus pyogenes MGAS5005]; ferrichrome-binding protein complement(405648..406586) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111893 YP_002996150.1 CDS fhuA NC_012891.1 406611 407393 R similar to ferrichrome transport ATP-binding protein [Streptococcus pyogenes MGAS5005]; ferrichrome transport ATP-binding protein complement(406611..407393) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111896 YP_002996151.1 CDS murE NC_012891.1 407642 409087 R involved in cell wall formation; peptidoglycan synthesis; cytoplasmic enzyme; catalyzes the addition of lysine to UDP-N-acetylmuramoyl-L-alanyl-D-glutamate forming UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysine; UDP-N-acetylmuramoylalanyl-D-glutamate--L-lysine ligase complement(407642..409087) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111892 YP_002996152.1 CDS SDEG_0436 NC_012891.1 409175 410809 D similar to export protein for polysaccharides and teichoic acids [Streptococcus pyogenes MGAS5005]; polysaccharides and teichoicacids export protein 409175..410809 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111686 YP_002996153.1 CDS SDEG_0437 NC_012891.1 410795 411880 R similar to transposase [Streptococcus pyogenes MGAS10394]; transposase complement(410795..411880) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112101 YP_002996154.1 CDS upp NC_012891.1 412094 412723 D Catalyzes the formation of uracil and 5-phospho-alpha-D-ribosy 1-diphosphate from UMP and diphosphate; uracil phosphoribosyltransferase 412094..412723 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112102 YP_002996155.1 CDS clpP NC_012891.1 412945 413535 D hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates; ATP-dependent Clp protease proteolytic subunit 412945..413535 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111943 YP_002996156.1 CDS SDEG_0440 NC_012891.1 413921 414217 D similar to hypothetical protein gbs2095 [Streptococcus agalactiae NEM316]; hypothetical protein 413921..414217 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111624 YP_002996157.1 CDS SDEG_0441 NC_012891.1 414292 414762 D similar to hypothetical proteinSMU.1671c [Streptococcus mutans UA159]; hypothetical protein 414292..414762 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112103 YP_002996158.1 CDS SDEG_0442 NC_012891.1 414738 415028 D similar to conserved hypothetical protein [Streptococcus pyogenes M1GAS]; hypothetical protein 414738..415028 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112104 YP_002996159.1 CDS livK NC_012891.1 415232 416404 D similar to ABC transporter, branched chain amino acid-binding protein [Streptococcus mutans UA159]; branched-chain amino acid ABC transporter substrate-binding protein 415232..416404 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112105 YP_002996160.1 CDS livH NC_012891.1 416593 417462 D similar to branched chain amino acid ABC transporter, permease protein [Streptococcus mutans UA159]; branched-chain amino acid ABC transporter permease 416593..417462 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110899 YP_002996161.1 CDS livM NC_012891.1 417466 418419 D similar to branched chain amino acid ABC transporter, permease protein [Streptococcus mutans UA159]; branched-chain amino acid ABC transporter permease 417466..418419 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110898 YP_002996162.1 CDS livG NC_012891.1 418420 419184 D similar to branched-chain amino acid ABC transporter ATP binding protein [Streptococcus thermophilus CNRZ1066]; branched-chain amino acid ABC transporter ATP binding protein 418420..419184 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110900 YP_002996163.1 CDS livF NC_012891.1 419184 419894 D similar to ABC-type branched-chain amino acid transport system ATPase component [Streptococcus suis 98HAH33]; branched-chain amino acid ABC transporter ATPase 419184..419894 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110897 YP_002996164.1 CDS SDEG_0448 NC_012891.1 419939 420601 D similar to hypothetical protein STRINF 01997 [Streptococcus infantarius subsp. infantarius ATCC BAA-102]; hypothetical protein 419939..420601 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110896 YP_002996165.1 CDS tmk NC_012891.1 420688 421323 D catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to thymidine monophosphate (dTMP) to form thymidine diphosphate (dTDP); thymidylate kinase 420688..421323 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112106 YP_002996166.1 CDS SDEG_0450 NC_012891.1 421339 422211 D catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the delta' subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA.; DNA polymerase III subunit delta' 421339..422211 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110526 YP_002996167.1 CDS yabA NC_012891.1 422208 423008 D similar to DNA replicationintiation control protein YabA [Streptococcus pyogenes M1GAS]; Involved in initiation control of chromosomereplication.; initiation-control protein, YabA-like 422208..423008 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112107 YP_002996168.1 CDS SDEG_0452 NC_012891.1 423001 423324 D in Bacillus subtilis this protein is involved in the negative regulation of DNA replication initiation; interacts with DnaN and DnaA; DNA replication intiation control protein YabA 423001..423324 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111957 YP_002996169.1 CDS SDEG_0453 NC_012891.1 423329 424192 D similar to corrin /porphyrin methyltransferase [Streptococcus pyogenes MGAS6180]; corrin/porphyrin methyltransferase 423329..424192 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112108 YP_002996170.1 CDS SDEG_0454 NC_012891.1 424219 424611 D similar to hypothetical membrane associated protein [Streptococcus pyogenes MGAS5005]; hypothetical protein 424219..424611 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112109 YP_002996171.1 CDS cutC NC_012891.1 424658 425287 R similar to copper homeostasis protein [Streptococcus pyogenes MGAS6180]; copper homeostasis protein complement(424658..425287) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112110 YP_002996172.1 CDS SDEG_0456 NC_012891.1 425404 426495 D catalyzes the formation of 3-phosphonooxypyruvate and glutamate from O-phospho-L-serine and 2-oxoglutarate; required both in major phosphorylated pathway of serine biosynthesis and in the biosynthesis of pyridoxine; phosphoserine aminotransferase 425404..426495 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111654 YP_002996173.1 CDS SDEG_0457 NC_012891.1 426521 427072 D similar to acetyltransferase [Streptococcus equi]; GNAT family acetyltransferase 426521..427072 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112111 YP_002996174.1 CDS ogt NC_012891.1 427133 427630 D similar to methylated-DNA-protein-cysteine S-methyltransferase[Streptococcus mutans UA159]; methylated-DNA-protein- cysteinemethyltransferase 427133..427630 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112112 YP_002996175.1 CDS SDEG_0459 NC_012891.1 427627 427983 D similar to arsenate reductase family protein [Streptococcus pyogenes MGAS10270]; arsenate reductase 427627..427983 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111732 YP_002996176.1 CDS SDEG_0460 NC_012891.1 428034 428342 R similar to hypothetical protein SAG1540 [Streptococcus agalactiae 2603V/R]; hypothetical protein complement(428034..428342) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112113 YP_002996177.1 CDS SDEG_0461 NC_012891.1 428344 428733 R similar to glyoxalase family protein [Streptococcus agalactiae 2603V/R]; glyoxalase complement(428344..428733) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112114 YP_002996178.1 CDS SDEG_0462 NC_012891.1 428831 429766 R similar to sugar-binding transcriptional regulator; LacI family transcriptional regulator complement(428831..429766) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112115 YP_002996179.1 CDS SDEG_0463 NC_012891.1 429763 430575 R similar to HAD superfamily hydrolase [Streptococcus agalactiae 2603V/R]; haloacid dehalogenase family hydrolase complement(429763..430575) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112116 YP_002996180.1 CDS exoA NC_012891.1 430704 431531 R similar to 3'-exo-deoxyribonuclease [Streptococcus pyogenes M1 GAS]; 3'-exo-deoxyribonuclease complement(430704..431531) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112117 YP_002996181.1 CDS SDEG_0465 NC_012891.1 431820 432452 D similar to hemolysis inducing protein [Streptococcus mutans UA159]; hypothetical protein 431820..432452 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111874 YP_002996182.1 CDS lctP NC_012891.1 432751 434280 D similar to L-lactate permease; L-lactate permease 432751..434280 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112118 YP_002996183.1 CDS SDEG_0467 NC_012891.1 434422 435603 D similar to lactate oxidase [Streptococcus pyogenes MGAS8232]; lactate oxidase 434422..435603 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110889 YP_002996184.1 CDS cepA NC_012891.1 435855 437222 D similar to cell envelope proteinase A [Streptococcus pyogenes]; cell envelope proteinase A 435855..437222 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112119 YP_002996185.1 CDS cepA NC_012891.1 437173 438603 D similar to cell envelope proteinase A [Streptococcus pyogenes]; cell envelope proteinase A 437173..438603 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111611 YP_002996186.1 CDS cepA NC_012891.1 438674 440605 D similar to cell envelope proteinase A [Streptococcus pyogenes]; cell envelope proteinase A 438674..440605 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111612 YP_002996187.1 CDS SDEG_0471 NC_012891.1 440818 442482 D similar to conserved hypothetical protein [Streptococcus suis 89/1591]; cell shape-determining protein 440818..442482 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111613 YP_002996188.1 CDS SDEG_0472 NC_012891.1 442767 443474 D similar to hypothetical membrane spanning protein [Streptococcus pyogenes MGAS2096]; hypothetical protein 442767..443474 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112120 YP_002996189.1 CDS metS NC_012891.1 443739 445739 D methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content; methionyl-tRNA synthetase 443739..445739 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112121 YP_002996190.1 CDS nrdF1 NC_012891.1 446272 447285 D similar to ribonucleoside-diphosphate reductase beta chain [Streptococcus pyogenes MGAS2096]; ribonucleotide-diphosphate reductase subunit beta 446272..447285 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110936 YP_002996191.1 CDS nrdI NC_012891.1 447289 447762 D in Salmonella NrdI has a stimulatory effect on the ribonucleotide reductase activity of NrdH with NrdEF; ribonucleotide reductase stimulatory protein 447289..447762 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111719 YP_002996192.1 CDS nrdE1 NC_012891.1 447746 449932 D Catalyzes the rate-limiting step in dNTP synthesis; ribonucleotide-diphosphate reductase subunit alpha 447746..449932 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111722 YP_002996193.1 CDS brnQ-1 NC_012891.1 450230 451564 D similar to branched-chain amino acid transport system II carrier protein [Streptococcus agalactiae 2603V/R]; branched-chain amino acid transport system II carrier protein 450230..451564 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111717 YP_002996194.1 CDS SDEG_0478 NC_012891.1 451902 452765 R similar to transposase [Streptococcus pyogenes MGAS2096]; transposase complement(451902..452765) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111598 YP_002996195.1 CDS SDEG_0479 NC_012891.1 453629 453865 D similar to hypothetical protein spr0700 [Streptococcus pneumoniae R6]; hypothetical protein 453629..453865 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112122 YP_002996196.1 CDS fabG NC_012891.1 453858 454556 D Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis; 3-ketoacyl-ACP reductase 453858..454556 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112123 YP_002996197.1 CDS SDEG_0481 NC_012891.1 454813 455262 D similar to conserved hypothetical protein [Streptococcus agalactiae H36B]; hypothetical protein 454813..455262 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112124 YP_002996198.1 CDS SDEG_0482 NC_012891.1 455264 456223 D similar to hypothetical protein SPs1547 [Streptococcus pyogenes SSI-1]; hypothetical protein 455264..456223 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112125 YP_002996199.1 CDS SDEG_0483 NC_012891.1 456557 457894 D similar to phosphoglycerate transporter protein [Streptococcus pyogenes MGAS6180]; phosphoglycerate transporter protein 456557..457894 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112126 YP_002996200.1 CDS glmU NC_012891.1 458066 459448 D forms a homotrimer; catalyzes the acetylation of glucosamine-1-phosphate and uridylation of N-acetylglucosamine-1-phosphate to produce UDP-GlcNAc; function in cell wall synthesis; bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase 458066..459448 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112127 YP_002996201.1 CDS SDEG_0485 NC_012891.1 459479 460033 D similar to ADP-ribose pyrophosphatase [Streptococcus pyogenes MGAS10750]; ADP-ribose pyrophosphatase 459479..460033 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111989 YP_002996202.1 CDS mtnN NC_012891.1 460303 460998 D enables the cleavage of the glycosidic bond in both 5'-methylthioadenosine and S-adenosylhomocysteine; 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase 460303..460998 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112128 YP_002996203.1 CDS scaR NC_012891.1 461071 461718 R similar to iron-dependent repressor [Streptococcus pyogenes MGAS6180]; iron-dependent repressor complement(461071..461718) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110947 YP_002996204.1 CDS mtsA NC_012891.1 461864 462796 D similar to manganese-binding protein [Streptococcus pyogenes MGAS5005]; manganese-binding protein 461864..462796 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110464 YP_002996205.1 CDS mtsB NC_012891.1 462861 463586 D similar to manganese transport system ATP-binding protein [Streptococcus pyogenes MGAS5005]; manganese transport system ATP-binding protein 462861..463586 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110948 YP_002996206.1 CDS mtsC NC_012891.1 463587 464435 D similar to metal cation ABC transporter membrane protein [Streptococcus pyogenes str. Manfredo]; metal cation ABC transporter membrane protein 463587..464435 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111678 YP_002996207.1 CDS SDEG_0491 NC_012891.1 464566 465372 R similar to peptidyl-prolyl cis-trans isomerase [Streptococcus pyogenes MGAS5005]; peptidyl-prolyl cis-trans isomerase complement(464566..465372) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111679 YP_002996208.1 CDS ftsK NC_012891.1 465491 467998 D similar to cell division protein [Streptococcus pyogenes MGAS5005]; cell division protein 465491..467998 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112129 YP_002996209.1 CDS SDEG_0493 NC_012891.1 468067 468420 R similar to integral membrane protein [Streptococcus pyogenes MGAS5005]; integral membrane protein complement(468067..468420) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111919 YP_002996210.1 CDS SDEG_0494 NC_012891.1 468576 469604 R similar to transposase [Streptococcus pyogenes MGAS10270]; transposase complement(468576..469604) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112130 YP_002996211.1 CDS rplK NC_012891.1 469762 470265 D binds directly to 23S ribosomal RNA; 50S ribosomal protein L11 469762..470265 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112131 YP_002996212.1 CDS rplA NC_012891.1 470371 471060 D in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA; 50S ribosomal protein L1 470371..471060 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111066 YP_002996213.1 CDS pyrH NC_012891.1 471967 472695 D Catalyzes the phosphorylation of UMP to UDP; uridylate kinase 471967..472695 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111058 YP_002996214.1 CDS frr NC_012891.1 472724 473281 D Rrf; Frr; ribosome-recycling factor; release factor 4; RF4; recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G; A GTPase-dependent process results in release of 50S from 70S; inhibited by release factor RF-1; essential for viability; structurally similar to tRNAs; ribosome recycling factor 472724..473281 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111344 YP_002996215.1 CDS SDEG_0499 NC_012891.1 473390 474247 D similar to s1 RNA binding domain [Streptococcus pyogenes MGAS5005]; s1 RNA binding domain 473390..474247 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111909 YP_002996216.1 CDS msrA NC_012891.1 474320 474829 D this stereospecific enzymes reduces the S isomer of methionine sulfoxide while MsrB reduces the R form; provides protection against oxidative stress; methionine sulfoxide reductase A 474320..474829 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112132 YP_002996217.1 CDS SDEG_0501 NC_012891.1 474826 475041 D similar to D-alanyl-D-alanine carboxypeptidase [Streptococcus pyogenes MGAS5005]; hypothetical protein 474826..475041 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110943 YP_002996218.1 CDS SDEG_0502 NC_012891.1 475200 476396 D similar to surface antigen [Streptococcus pyogenes MGAS5005]; surface antigen 475200..476396 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112133 YP_002996219.1 CDS SDEG_0503 NC_012891.1 476620 478479 D in group A Streptococci this protein was found to cross react with anti myosin antibodies and may play a role in rheumatic fever; myosin-cross-reactive antigen 476620..478479 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112134 YP_002996220.1 CDS phoH NC_012891.1 478640 479701 D similar to PhoH protein [Streptococcus pyogenes MGAS5005]; phosphate starvation-induced protein 478640..479701 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112135 YP_002996221.1 CDS SDEG_0505 NC_012891.1 479748 480323 D similar to uracil DNA glycosylase superfamily protein [Streptococcus pyogenes MGAS5005]; uracil DNA glycosylase 479748..480323 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111292 YP_002996222.1 CDS SDEG_0506 NC_012891.1 480431 480979 D similar to hypothetical protein M5005 Spy 0388 [Streptococcus pyogenes MGAS5005]; metalloprotease 480431..480979 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110529 YP_002996223.1 CDS dgk NC_012891.1 480960 481367 D similar to diacylglycerol kinase [Streptococcus pyogenes MGAS5005]; diacylglycerol kinase 480960..481367 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110530 YP_002996224.1 CDS era NC_012891.1 481488 482384 D Era; Escherichia coli Ras-like protein; Bex; Bacillus Era-complementing segment; essential protein in Escherichia coli that is involved in many cellular processes; GTPase; binds the cell membrane through apparent C-terminal domain; mutants are arrested during the cell cycle; Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome; GTP-binding protein Era 481488..482384 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111671 YP_002996225.1 CDS SDEG_0509 NC_012891.1 482571 482924 D similar to phosphohydrolase [Streptococcus pyogenes MGAS10750]; phosphohydrolase 482571..482924 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111872 YP_002996226.1 CDS SDEG_0510 NC_012891.1 482707 484113 R similar to bacteriocin processing peptidase / bacteriocin export ABC transporter [Streptococcus pyogenes MGAS10750]; bacteriocin processing peptidase complement(482707..484113) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110531 YP_002996227.1 CDS SDEG_0511 NC_012891.1 484417 484644 D similar to hypothetical protein MGAS10750 Spy0398 [Streptococcus pyogenes MGAS10750]; hypothetical protein 484417..484644 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110532 YP_002996228.1 CDS SDEG_0512 NC_012891.1 484681 485010 D similar to hypothetical protein MGAS10750 Spy0399 [Streptococcus pyogenes MGAS10750]; hypothetical protein 484681..485010 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110533 YP_002996229.1 CDS blpM NC_012891.1 485418 485657 D similar to bacteriocin BlpM [Streptococcus pneumoniae SP6-BS73]; bacteriocin BlpM-like 485418..485657 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110534 YP_002996230.1 CDS blp NC_012891.1 485795 485995 D similar to bacteriocin Blp [Streptococcus pneumoniae G54]; bacteriocin 485795..485995 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111597 YP_002996231.1 CDS fasA NC_012891.1 486540 487289 D similar to response regulator FasA [Streptococcus pyogenes MGAS10750]; response regulator 486540..487289 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112378 YP_002996232.1 CDS SDEG_0516 NC_012891.1 487290 488624 D similar to sensory transduction protein kinase [Streptococcus pyogenes MGAS10750]; sensory transduction protein kinase 487290..488624 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111881 YP_002996233.1 CDS SDEG_0517 NC_012891.1 488685 488810 R similar to hypothetical protein MGAS10750 Spy0405 [Streptococcus pyogenes MGAS10750]; hypothetical protein complement(488685..488810) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110535 YP_002996234.1 CDS silD NC_012891.1 488901 490265 R similar to SilD [Streptococcus pyogenes]; hypothetical protein complement(488901..490265) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110536 YP_002996235.1 CDS SDEG_0519 NC_012891.1 490276 492429 R similar to bacteriocin processing peptidase / bacteriocin export ABC transporter [Streptococcus pyogenes MGAS10750]; bacteriocin processing peptidase complement(490276..492429) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110486 YP_002996236.1 CDS SDEG_0520 NC_012891.1 492824 493852 D similar to transposase [Streptococcus pyogenes MGAS10270]; transposase 492824..493852 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110537 YP_002996237.1 CDS SDEG_0521 NC_012891.1 494133 494333 D similar to hypothetical membrane associated protein [Streptococcus pyogenes MGAS10270]; hypothetical protein 494133..494333 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110538 YP_002996238.1 CDS SDEG_0522 NC_012891.1 494628 494822 D similar to hypothetical protein M6 Spy0424 [Streptococcus pyogenes MGAS10394]; hypothetical protein 494628..494822 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110539 YP_002996239.1 CDS SDEG_0523 NC_012891.1 494872 495132 D similar to hypothetical protein SPs1514 [Streptococcus pyogenes SSI-1]; hypothetical protein 494872..495132 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110540 YP_002996240.1 CDS SDEG_0524 NC_012891.1 495348 495758 D similar to hypothetical protein MGAS10750 Spy0413 [Streptococcus pyogenes MGAS10750]; hypothetical protein 495348..495758 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110541 YP_002996241.1 CDS SDEG_0525 NC_012891.1 495788 495931 R similar to hypothetical protein M6 Spy0427 [Streptococcus pyogenes MGAS10394]; hypothetical protein complement(495788..495931) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110542 YP_002996242.1 CDS SDEG_0526 NC_012891.1 496274 496504 D similar to CAAX amino terminal protease family protein [Streptococcus agalactiae NEM316]; CAAX amino terminal protease 496274..496504 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110543 YP_002996243.1 CDS SDEG_0527 NC_012891.1 496903 497667 D similar to hypothetical protein MGAS2096 Spy0420 [Streptococcus pyogenes MGAS2096]; hypothetical protein 496903..497667 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110544 YP_002996244.1 CDS SDEG_0528 NC_012891.1 497689 498717 R similar to hypothetical protein SAG1491 [Streptococcus agalactiae 2603V/R]; hypothetical protein complement(497689..498717) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110545 YP_002996245.1 CDS mutR NC_012891.1 498944 499798 D similar to transcriptional regulator [Streptococcus pyogenes MGAS10750]; transcriptional regulator 498944..499798 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110546 YP_002996246.1 CDS fpg NC_012891.1 499980 500807 D Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases; formamidopyrimidine-DNA glycosylase 499980..500807 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111694 YP_002996247.1 CDS coaE NC_012891.1 500777 501397 D catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; involved in coenzyme A biosynthesis; dephospho-CoA kinase 500777..501397 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111907 YP_002996248.1 CDS SDEG_0532 NC_012891.1 501858 502559 D similar to ABC transporter ATP binding protein [Streptococcus agalactiae 2603V/R]; ABC transporter ATP-binding protein 501858..502559 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110547 YP_002996249.1 CDS SDEG_0533 NC_012891.1 502549 504186 D similar to hypothetical protein SAG1486 [Streptococcus agalactiae 2603V/R]; hypothetical protein 502549..504186 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110548 YP_002996250.1 CDS SDEG_0534 NC_012891.1 504296 505798 D similar to ATPase [Streptococcus pyogenes MGAS9429]; ATPase 504296..505798 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110549 YP_002996251.1 CDS SDEG_0535 NC_012891.1 506058 507179 D similar to multidrug resistance protein B [Streptococcus pyogenes MGAS10394]; multidrug resistance protein B 506058..507179 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110550 YP_002996252.1 CDS rpmG NC_012891.1 507176 507322 D in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif; 50S ribosomal protein L33 507176..507322 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110551 YP_002996253.1 CDS secG NC_012891.1 507368 507604 D similar to translocase [Streptococcus pyogenes MGAS315]; preprotein translocase subunit SecG 507368..507604 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110552 YP_002996254.1 CDS SDEG_0538 NC_012891.1 507716 510031 D similar to exoribonuclease II [Streptococcus pyogenes MGAS10750]; exoribonuclease II 507716..510031 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110479 YP_002996255.1 CDS smpB NC_012891.1 510034 510501 D binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation; SsrA-binding protein 510034..510501 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110553 YP_002996256.1 CDS SDEG_0540 NC_012891.1 511097 512023 R similar to sugar transferase [Streptococcus pyogenes MGAS315]; sugar transferase complement(511097..512023) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110492 YP_002996257.1 CDS sdzD NC_012891.1 512160 513344 R similar to phage-encoded extracellular streptodornase D [Streptococcus pyogenes];deoxyribonuclease; streptodornase D type complement(512160..513344) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110554 YP_002996258.1 CDS gloA NC_012891.1 513690 514067 R similar to lactoylglutathione lyase [Streptococcus pyogenes MGAS315]; lactoylglutathione lyase complement(513690..514067) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110476 YP_002996259.1 CDS SDEG_0543 NC_012891.1 514077 514742 R similar to NAD(P)H-flavin oxidoreductase [Streptococcus pyogenes MGAS315]; NAD(P)H-flavin oxidoreductase complement(514077..514742) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112006 YP_002996260.1 CDS SDEG_0544 NC_012891.1 514786 515871 R similar to Xaa-Pro dipeptidase [Streptococcus pyogenes MGAS10394]; Xaa-Pro dipeptidase complement(514786..515871) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110555 YP_002996261.1 CDS ccpA NC_012891.1 516045 517046 D similar to catabolite control protein A [Streptococcus pyogenes MGAS5005]; catabolite control protein A 516045..517046 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110556 YP_002996262.1 CDS amyS NC_012891.1 517200 518663 D converts 1,4-alpha-D-glucans to maltodextrin; alpha-amylase 517200..518663 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111609 YP_002996263.1 CDS SDEG_0547 NC_012891.1 518740 519738 D similar to glycosyltransferase [Streptococcus pyogenes MGAS5005]; glycosyltransferase 518740..519738 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112326 YP_002996264.1 CDS SDEG_0548 NC_012891.1 519740 521074 D similar to 1,2-diacylglycerol 3-glucosyltransferase [Streptococcus pyogenes MGAS10270]; 1,2-diacylglycerol 3-glucosyltransferase 519740..521074 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110557 YP_002996265.1 CDS thrS NC_012891.1 521498 523441 D catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr); threonyl-tRNA synthetase 521498..523441 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110558 YP_002996266.1 CDS SDEG_0550 NC_012891.1 523571 524563 D similar to ABC transporter ATP-binding protein [Streptococcus pyogenesstr. Manfredo]; ABC transporter ATP-binding protein 523571..524563 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110521 YP_002996267.1 CDS SDEG_0551 NC_012891.1 524565 525197 D similar to daunorubicin resistance transmembrane protein [Streptococcus pyogenes MGAS5005]; daunorubicin resistance transmembrane protein 524565..525197 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110559 YP_002996268.1 CDS SDEG_0552 NC_012891.1 525185 525382 D similar to daunorubicin resistance transmembrane protein [Streptococcus pyogenes MGAS10750]; daunorubicin resistance transmembrane protein 525185..525382 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110560 YP_002996269.1 CDS SDEG_0553 NC_012891.1 525384 526169 D similar to ABC transporter permease protein [Streptococcus pyogenes MGAS10750]; ABC transporter permease 525384..526169 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110561 YP_002996270.1 CDS SDEG_0554 NC_012891.1 526273 527262 R similar to DhaK; in Lactococcus lactis this protein froms a stable complex with DhaS and activates transcription of the dha operon in the presence of dihydroxyacetone; DhaKLM operon coactivator DhaQ complement(526273..527262) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110562 YP_002996271.1 CDS SDEG_0555 NC_012891.1 527277 527813 R similar to hypothetical protein SpyM51438 [Streptococcus pyogenes str.Manfredo]; hypothetical protein complement(527277..527813) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110563 YP_002996272.1 CDS SDEG_0556 NC_012891.1 527965 528954 D with DhaL and DhaM forms dihydroxyacetone kinase, which is responsible for phosphorylating dihydroxyacetone; DhaK is the dihydroxyacetone binding subunit of the dihydroxyacetone kinase; dihydroxyacetone kinase subunit DhaK 527965..528954 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110564 YP_002996273.1 CDS SDEG_0557 NC_012891.1 528965 529540 D similar to dihydroxyacetone kinase family protein [Streptococcus pyogenes str. Manfredo]; dihydroxyacetone kinase 528965..529540 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110565 YP_002996274.1 CDS SDEG_0558 NC_012891.1 529540 529914 D similar to dihydroxyacetone kinase phosphotransfer protein [Streptococcus pyogenes MGAS10394]; PTS system transporter subunit IIA 529540..529914 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110566 YP_002996275.1 CDS SDEG_0559 NC_012891.1 529932 530642 D similar to glycerol uptake facilitator protein [Streptococcus pyogenes MGAS10394]; glycerol uptake facilitator protein 529932..530642 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110567 YP_002996276.1 CDS SDEG_0560 NC_012891.1 530776 531345 D similar to hypothetical protein SpyM51433 [Streptococcus pyogenes str.Manfredo]; hypothetical protein 530776..531345 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110568 YP_002996277.1 CDS SDEG_0561 NC_012891.1 531308 532429 D similar to acetyl-CoA acetyltransferase [Streptococcus pyogenes MGAS5005]; acetyl-CoA acetyltransferase 531308..532429 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110569 YP_002996278.1 CDS SDEG_0562 NC_012891.1 532419 533663 D similar to long-chain-fatty-acid-CoA ligase [Streptococcus pyogenes MGAS5005]; long-chain-fatty-acid-CoA ligase 532419..533663 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110570 YP_002996279.1 CDS SDEG_0563 NC_012891.1 533740 534753 D similar to hypothetical cytosolic protein [Streptococcus pyogenes MGAS5005]; hypothetical protein 533740..534753 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110571 YP_002996280.1 CDS SDEG_0564 NC_012891.1 534849 535295 R similar to aminoacid (glutamine) ABC transporter permease protein [Streptococcus thermophilus CNRZ1066]; ABC transporter permease complement(534849..535295) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110572 YP_002996281.1 CDS glnP NC_012891.1 535274 535495 R similar to amino acid ABC transporter integral membrane protein [Streptococcus mutans UA159]; amino acid ABC transporter permease complement(535274..535495) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110573 YP_002996282.1 CDS SDEG_0566 NC_012891.1 535510 536211 R similar to hypothetical protein gbs0689 [Streptococcus agalactiae NEM316]; hypothetical protein complement(535510..536211) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112004 YP_002996283.1 CDS SDEG_0567 NC_012891.1 536225 537031 R similar to amino acid ABC transporter, amino acid-binding protein [Streptococcus agalactiae 2603V/R]; amino acid ABC transporter substrate-binding protein complement(536225..537031) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110574 YP_002996284.1 CDS SDEG_0568 NC_012891.1 537025 537897 R similar to aminoacid (glutamine) ABC transporter ATP-binding protein [Streptococcus thermophilus CNRZ1066]; ABC transporter ATP-binding protein complement(537025..537897) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110575 YP_002996285.1 CDS vicR NC_012891.1 538077 538787 D similar to two-component response regulator [Streptococcus pyogenes MGAS5005]; two-component response regulator 538077..538787 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110576 YP_002996286.1 CDS vicK NC_012891.1 538780 540132 D similar to two-component sensor histidine kinase [Streptococcus pyogenes MGAS5005]; two-component sensor histidine kinase 538780..540132 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111949 YP_002996287.1 CDS vicX NC_012891.1 540136 540945 D similar to Zn-dependent hydrolase [Streptococcus pyogenes MGAS5005]; Zn-dependent hydrolase 540136..540945 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111948 YP_002996288.1 CDS rnc NC_012891.1 541703 542395 D cytoplasmic enzyme involved in processing rRNA and some mRNAs; substrates typically have dsRNA regions; forms a homodimer; have N-terminal nuclease and C-terminal RNA-binding domains; requires magnesium as preferred ion for activity; ribonuclease III 541703..542395 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111950 YP_002996289.1 CDS smc NC_012891.1 542396 545941 D similar to chromosome partition protein [Streptococcus pyogenes MGAS5005]; chromosome partition protein 542396..545941 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110933 YP_002996290.1 CDS cspA NC_012891.1 546281 546928 D similar to CspA [Streptococcus agalactiae]; cell-surface protease required for virulence cell 546281..546928 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110490 YP_002996291.1 CDS SDEG_0575 NC_012891.1 547168 548010 D similar to reticulocyte binding protein [Streptococcus agalactiae 515]; reticulocyte binding protein 547168..548010 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111652 YP_002996292.1 CDS SDEG_0576 NC_012891.1 548250 548636 D similar to HAD superfamily hydrolase [Streptococcus pyogenes MGAS5005]; hydrolase 548250..548636 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110577 YP_002996293.1 CDS SDEG_0577 NC_012891.1 548680 549048 D similar to HAD superfamily hydrolase [Streptococcus pyogenes MGAS5005]; hydrolase 548680..549048 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110578 YP_002996294.1 CDS SDEG_0578 NC_012891.1 549052 549876 D similar to HAD superfamily hydrolase [Streptococcus pyogenes MGAS5005]; hydrolase 549052..549876 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110579 YP_002996295.1 CDS ftzY NC_012891.1 549876 551426 D similar to cell division protein [Streptococcus pyogenes MGAS5005]; cell division protein 549876..551426 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110580 YP_002996296.1 CDS SDEG_0580 NC_012891.1 551479 552597 R similar to multidrug resistance protein B [Streptococcus pyogenes MGAS5005]; multidrug resistance protein B complement(551479..552597) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111980 YP_002996297.1 CDS SDEG_0581 NC_012891.1 552473 552844 R similar to major facilitator superfamily protein [Streptococcus pyogenes str. Manfredo]; major facilitator superfamily protein complement(552473..552844) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110581 YP_002996298.1 CDS SDEG_0582 NC_012891.1 553172 554014 D similar to transcription antiterminator; transcription antiterminator 553172..554014 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110582 YP_002996299.1 CDS SDEG_0583 NC_012891.1 554016 555878 D similar to PTS system beta-glucoside-specific IIABC component [Streptococcus pyogenes MGAS5005]; PTS system protein 554016..555878 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110583 YP_002996300.1 CDS bglA NC_012891.1 555897 557321 D similar to 6-phospho-beta-glucosidase [Streptococcus pyogenes MGAS5005]; 6-phospho-beta-glucosidase 555897..557321 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110584 YP_002996301.1 CDS SDEG_0585 NC_012891.1 557420 558259 R similar to hypothetical membrane spanning protein [Streptococcus pyogenesMGAS5005]; hypothetical protein complement(557420..558259) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112372 YP_002996302.1 CDS SDEG_0586 NC_012891.1 558235 559137 R similar to hypothetical membrane spanning protein [Streptococcus pyogenesMGAS5005]; hypothetical protein complement(558235..559137) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110585 YP_002996303.1 CDS SDEG_0587 NC_012891.1 559284 559439 R similar to hypothetical protein MGAS9429 Spy0471 [Streptococcus pyogenes MGAS9429]; hypothetical protein complement(559284..559439) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110586 YP_002996304.1 CDS SDEG_0588 NC_012891.1 559611 560096 D similar to hypothetical protein spr1892 [Streptococcus pneumoniae R6]; hypothetical protein 559611..560096 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110587 YP_002996305.1 CDS phoP NC_012891.1 560183 560890 D similar to response regulator [Streptococcus pneumoniae R6]; two-component response regulator 560183..560890 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110588 YP_002996306.1 CDS pnpS NC_012891.1 560891 562219 D similar to histidine kinase [Streptococcus pneumoniae R6]; two-component sensor histidine kinase 560891..562219 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111293 YP_002996307.1 CDS SDEG_0591 NC_012891.1 562377 563261 D similar to phosphate ABC transporter, phosphate-binding protein [Streptococcus pneumoniae SP9-BS68]; phosphate ABC transporter substrate-binding protein 562377..563261 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111297 YP_002996308.1 CDS SDEG_0592 NC_012891.1 563379 564242 D similar to phosphate ABC transporter permease protein [Streptococcus pneumoniae TIGR4]; phosphate ABC transporter 563379..564242 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110589 YP_002996309.1 CDS SDEG_0593 NC_012891.1 564235 565050 D similar to phosphate ABC transporter permease protein [Streptococcus pneumoniae TIGR4]; phosphate ABC transporter 564235..565050 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110590 YP_002996310.1 CDS SDEG_0594 NC_012891.1 565052 565804 D ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation; phosphate transporter ATP-binding protein 565052..565804 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110591 YP_002996311.1 CDS SDEG_0595 NC_012891.1 565822 566472 D similar to negative regulator of pho regulon for phosphate transport [Streptococcus pneumoniae R6]; negative regulator of pho regulon for phosphate transport 565822..566472 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110592 YP_002996312.1 CDS SDEG_0596 NC_012891.1 567272 569404 D similar to hypothetical protein SPy 0580 [Streptococcus pyogenes M1 GAS]; hypothetical protein 567272..569404 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110593 YP_002996313.1 CDS SDEG_0597 NC_012891.1 569346 569828 D similar to hypothetical protein M5005 Spy 0482 [Streptococcus pyogenes MGAS5005]; hypothetical protein 569346..569828 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110594 YP_002996314.1 CDS SDEG_0598 NC_012891.1 569892 570164 D similar to hypothetical protein SpyM51378 [Streptococcus pyogenes str. Manfredo]; hypothetical protein 569892..570164 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110595 YP_002996315.1 CDS ptsK NC_012891.1 570384 571376 D catalyzes the phosphorylation of the phosphocarrier protein HPr of the bacterial phosphotransferase system; HPr kinase/phosphorylase 570384..571376 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110596 YP_002996316.1 CDS lgt NC_012891.1 571373 572152 D transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein; prolipoprotein diacylglyceryl transferase 571373..572152 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111327 YP_002996317.1 CDS SDEG_0601 NC_012891.1 572174 572578 D similar to hypothetical protein M5005 Spy 0486 [Streptococcus pyogenes MGAS5005]; hypothetical protein 572174..572578 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110894 YP_002996318.1 CDS SDEG_0602 NC_012891.1 572575 573012 D similar to hypothetical protein MGAS10750 Spy0508 [Streptococcus pyogenes MGAS10750]; hypothetical protein 572575..573012 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110597 YP_002996319.1 CDS SDEG_0603 NC_012891.1 573176 573460 R similar to hypothetical protein SpyM51373 [Streptococcus pyogenes str.Manfredo]; hypothetical protein complement(573176..573460) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110598 YP_002996320.1 CDS SDEG_0604 NC_012891.1 573608 574585 D similar to peptidase [Streptococcus pyogenes str. Manfredo]; peptidase 573608..574585 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110599 YP_002996321.1 CDS SDEG_0605 NC_012891.1 574687 575973 D similar to peptidase family U32 [Streptococcus pyogenes MGAS5005]; peptidase family U32 574687..575973 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110600 YP_002996322.1 CDS SDEG_0606 NC_012891.1 576178 576390 D similar to hypothetical cytosolic protein [Streptococcus pyogenes MGAS10750]; hypothetical protein 576178..576390 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110601 YP_002996323.1 CDS SDEG_0607 NC_012891.1 576492 576635 R similar to hypothetical protein M28 Spy0473 [Streptococcus pyogenes MGAS6180]; hypothetical protein complement(576492..576635) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110602 YP_002996324.1 CDS SDEG_0608 NC_012891.1 576684 577811 R similar to hypothetical protein SAG1433 [Streptococcus agalactiae 2603V/R]; hypothetical protein complement(576684..577811) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110603 YP_002996325.1 CDS SDEG_0609 NC_012891.1 577915 578952 D similar to ammonium transporter (Amt) family protein [Streptococcus agalactiae A909]; ammonium transporter (Amt) family protein 577915..578952 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110604 YP_002996326.1 CDS lysS NC_012891.1 579029 580534 R class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1; lysyl-tRNA synthetase complement(579029..580534) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110605 YP_002996327.1 CDS SDEG_0611 NC_012891.1 580696 581598 D similar to HAD superfamily hydrolase [Streptococcus pyogenes MGAS5005]; hydrolase 580696..581598 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110913 YP_002996328.1 CDS SDEG_0612 NC_012891.1 581782 582402 R similar to phosphoglycerate mutase [Streptococcus pyogenes MGAS5005]; phosphoglycerate mutase complement(581782..582402) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110606 YP_002996329.1 CDS SDEG_0613 NC_012891.1 582415 582780 R similar to conserved hypothetical protein; integral membrane protein [Streptococcus mutans UA159]; hypothetical protein complement(582415..582780) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110607 YP_002996330.1 CDS SDEG_0614 NC_012891.1 582777 583262 R similar to transcription regulator [Streptococcus pyogenes MGAS8232]; transcriptional regulator complement(582777..583262) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110608 YP_002996331.1 CDS SDEG_0615 NC_012891.1 583348 583944 R similar to hypothetical protein SpyM51364 [Streptococcus pyogenes str.Manfredo]; hypothetical protein complement(583348..583944) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110609 YP_002996332.1 CDS SDEG_0616 NC_012891.1 584193 585035 R similar to N-acetylmuramoyl-L-alanine amidase [Streptococcus pyogenes MGAS10750]; N-acetylmuramoyl-L-alanine amidase complement(584193..585035) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112217 YP_002996333.1 CDS SDEG_0617 NC_012891.1 585359 585862 D similar to integral membrane protein [Streptococcus pyogenes MGAS10750]; integral membrane protein 585359..585862 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112218 YP_002996334.1 CDS SDEG_0618 NC_012891.1 585846 586229 D similar to hypothetical protein MGAS10270 Spy0496 [Streptococcus pyogenes MGAS10270]; hypothetical protein 585846..586229 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112219 YP_002996335.1 CDS SDEG_0619 NC_012891.1 586275 586799 R similar to glutathione peroxidase [Streptococcus pyogenes MGAS5005]; glutathione peroxidase complement(586275..586799) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112220 YP_002996336.1 CDS pepF NC_012891.1 586747 588546 R similar to oligoendopeptidase F [Streptococcus pyogenes MGAS5005]; oligoendopeptidase F complement(586747..588546) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112221 YP_002996337.1 CDS ppc NC_012891.1 588677 591508 D catalyzes the formation of oxaloacetate from phosphoenolpyruvate; phosphoenolpyruvate carboxylase 588677..591508 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111276 YP_002996338.1 CDS ftsW NC_012891.1 591696 593000 D similar to cell division protein [Streptococcus pyogenes MGAS5005]; cell division protein 591696..593000 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111302 YP_002996339.1 CDS SDEG_0623 NC_012891.1 593071 593580 D similar to DNA-directed RNA polymerase specialized sigma subunit [Streptococcus suis 98HAH33]; DNA-directed RNA polymerase specialized sigma subunit 593071..593580 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111976 YP_002996340.1 CDS SDEG_0624 NC_012891.1 593564 594643 D similar to hypothetical protein Sez 1324 [Streptococcus equi subsp. zooepidemicus MGCS10565]; hypothetical protein 593564..594643 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112222 YP_002996341.1 CDS SDEG_0625 NC_012891.1 594751 595965 D EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu; elongation factor Tu 594751..595965 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112223 YP_002996342.1 CDS SDEG_0626 NC_012891.1 596276 596707 D similar to hypothetical protein SAG1552 [Streptococcus agalactiae 2603V/R]; hypothetical protein 596276..596707 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112224 YP_002996343.1 CDS SDEG_0627 NC_012891.1 596871 597098 D similar to hypothetical protein gbs1605 [Streptococcus agalactiae NEM316]; hypothetical protein 596871..597098 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112225 YP_002996344.1 CDS SDEG_0628 NC_012891.1 597076 598299 D similar to glycosyl transferase group 2 family protein [Streptococcus agalactiae 2603V/R]; glycosyl transferase group 2 597076..598299 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112226 YP_002996345.1 CDS tpiA NC_012891.1 598465 599223 D Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate; triosephosphate isomerase 598465..599223 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112227 YP_002996346.1 CDS SDEG_0630 NC_012891.1 599291 600295 R similar to transposase [Streptococcus thermophilus LMD-9]; transposase complement(599291..600295) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111921 YP_002996347.1 CDS SDEG_0631 NC_012891.1 600321 600431 R similar to ORFA transposon ISSsa1 [Streptococcus sanguinis SK36]; ISSsa1 transposon OrfA complement(600321..600431) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112228 YP_002996348.1 CDS SDEG_0632 NC_012891.1 600458 600658 R similar to transposase [Streptococcus pyogenes MGAS10394]; transposase complement(600458..600658) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112229 YP_002996349.1 CDS SDEG_0633 NC_012891.1 600873 601583 R similar to ISSdy1 transposase OrfB [Streptococcus agalactiae 2603V/R]; ISSdy1, transposase OrfB complement(600873..601583) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112230 YP_002996350.1 CDS SDEG_0634 NC_012891.1 601619 601909 R similar to hypothetical protein gbs1310 [Streptococcus agalactiae NEM316]; hypothetical protein complement(601619..601909) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112231 YP_002996351.1 CDS SDEG_0635 NC_012891.1 601962 602135 R similar to L-lactate dehydrogenase (FMN-dependent) related alpha-hydroxy acid dehydrogenase [Pediococcus pentosaceus ATCC 25745]; L-lactate dehydrogenase (FMN-dependent) related alpha-hydroxy acid dehydrogenase complement(601962..602135) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112232 YP_002996352.1 CDS SDEG_0636 NC_012891.1 602259 603494 R similar to factor essential for expression of methicillin resistance [Streptococcus pyogenes MGAS5005]; factor essential for expression of methicillin resistance complement(602259..603494) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112233 YP_002996353.1 CDS murM NC_012891.1 603494 604726 R similar to UDP-N-acetylmuramoylpentapeptide-lysine N(6)-alanyltransferase/UDP-N-acetylmuramoyl pentapeptide-lysine N(6)-seryltransferase [Streptococcus pyogenes MGAS5005]; UDP-N-acetylmuramoylpentapeptide-lysine N(6)-alanyltransferase/UDP-N-acetylmuramoylpentapeptide- lysine N(6)-seryltransferase complement(603494..604726) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112234 YP_002996354.1 CDS SDEG_0638 NC_012891.1 604711 605520 R similar to HAD superfamily hydrolase [Streptococcus pyogenes MGAS9429]; HAD superfamily hydrolase complement(604711..605520) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111689 YP_002996355.1 CDS SDEG_0639 NC_012891.1 606001 607302 R similar to dGTP triphosphohydrolase [Streptococcus pyogenes MGAS5005]; dGTP triphosphohydrolase complement(606001..607302) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112235 YP_002996356.1 CDS SDEG_0640 NC_012891.1 607384 607791 D similar to hypothetical cytosolic protein [Streptococcus pyogenes MGAS5005]; hypothetical protein 607384..607791 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112236 YP_002996357.1 CDS pacL NC_012891.1 608119 610800 D similar to calcium-transporting ATPase [Streptococcus pyogenes M1GAS]; calcium-transporting ATPase 608119..610800 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112237 YP_002996358.1 CDS regR NC_012891.1 611410 612414 R similar to LacI family transcription regulator [Streptococcus pyogenes MGAS10394]; LacI family transcriptional regulator complement(611410..612414) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111749 YP_002996359.1 CDS SDEG_0643 NC_012891.1 612469 614394 R similar to oligohyaluronate lyase [Streptococcus pyogenes MGAS5005]; oligohyaluronate lyase complement(612469..614394) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111041 YP_002996360.1 CDS agaD NC_012891.1 614463 615344 R similar to N-acetylgalactosamine-specific phosphotransferase system (PTS); PTS system N-acetylgalactosamine-specific transporter subunit IID complement(614463..615344) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112238 YP_002996361.1 CDS SDEG_0645 NC_012891.1 615271 616053 R similar to PTS system N-acetylgalactosamine-specific IIC component [Streptococcus pyogenes MGAS5005]; PTS system N-acetylgalactosamine-specific transporter subunit IIC complement(615271..616053) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112314 YP_002996362.1 CDS agaV NC_012891.1 616072 616560 R similar to PTS system N-acetylgalactosamine-specific IIB component [Streptococcus pyogenes str. Manfredo]; PTS system protein complement(616072..616560) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112239 YP_002996363.1 CDS SDEG_0647 NC_012891.1 616596 617795 R similar to glucuronyl hydrolase [Streptococcus pyogenes MGAS5005]; glucuronyl hydrolase complement(616596..617795) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112316 YP_002996364.1 CDS SDEG_0648 NC_012891.1 617795 618232 R similar to N-acetylgalactosamine-specific phosphotransferase system (PTS); PTS system N-acetylgalactosamine-specific transporter subunit IIA complement(617795..618232) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112240 YP_002996365.1 CDS SDEG_0649 NC_012891.1 617862 618266 D similar to hypothetical protein M5005 Spy 0523 [Streptococcus pyogenes MGAS5005]; hypothetical protein 617862..618266 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112241 YP_002996366.1 CDS idnO NC_012891.1 618567 619361 D Involved in the nonphosphorylative, ketogenic oxidation of glucose and oxidizes gluconate to 5-ketogluconate; gluconate 5-dehydrogenase 618567..619361 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112242 YP_002996367.1 CDS SDEG_0651 NC_012891.1 619386 620027 D similar to hypothetical protein M5005 Spy 0525 [Streptococcus pyogenes MGAS5005]; hypothetical protein 619386..620027 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112047 YP_002996368.1 CDS SDEG_0652 NC_012891.1 620017 621057 D similar to 2-dehydro-3-deoxygluconokinase [Streptococcus pyogenes MGAS5005]; 2-dehydro-3-deoxygluconokinase 620017..621057 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112243 YP_002996369.1 CDS kgdA NC_012891.1 621062 621700 D catalyzes the formation of pyruvate and glyoxylate from 4-hydroxy-2-oxoglutarate; or pyruvate and D-glyceraldehyde 3-phosphate from 2-dehydro-3-deoxy-D-glyconate 6-phosphate; keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase 621062..621700 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112244 YP_002996370.1 CDS hylB NC_012891.1 621725 624928 D similar to hyaluronatelyase precursor HylB [Streptococcus equi subsp. zooepidemicus MGCS10565]; hyaluronate lyase 621725..624928 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110876 YP_002996371.1 CDS SDEG_0655 NC_012891.1 625316 625810 R similar to hypothetical protein SSA 0868 [Streptococcus sanguinis SK36]; hypothetical protein complement(625316..625810) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112046 YP_002996372.1 CDS SDEG_0656 NC_012891.1 625901 626209 R similar to hypothetical protein SAG0515 [Streptococcus agalactiae 2603V/R]; hypothetical protein complement(625901..626209) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112245 YP_002996373.1 CDS SDEG_0657 NC_012891.1 626379 626972 R similar to transposase [Streptococcus pyogenes str. Manfredo]; transposase complement(626379..626972) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112246 YP_002996374.1 CDS SDEG_0658 NC_012891.1 627230 627505 R similar to probable transposase TnpA (fragment) [Streptococcus pyogenes MGAS315]; transposase TnpA complement(627230..627505) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112247 YP_002996375.1 CDS SDEG_0659 NC_012891.1 627784 628428 D similar to beta-phosphoglucomutase [Streptococcus pyogenes MGAS10394]; beta-phosphoglucomutase 627784..628428 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112248 YP_002996376.1 CDS SDEG_0660 NC_012891.1 628659 630572 D similar to fructose-16-bisphosphatase [Streptococcus agalactiae 515]; fructose-1,6-bisphosphatase 628659..630572 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112249 YP_002996377.1 CDS SDEG_0661 NC_012891.1 630780 631952 D similar to iron-sulfur cluster-binding protein [Streptococcus pyogenes MGAS10394]; iron-sulfur cluster-binding protein 630780..631952 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112250 YP_002996378.1 CDS prfB NC_012891.1 632159 633154 D recognizes the termination signals UGA and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF2; in some organisms control of PrfB protein levels is maintained through a +1 ribosomal frameshifting mechanism; this protein is similar to release factor 1; peptide chain release factor 2 632159..633154 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112251 YP_002996379.1 CDS ftsE NC_012891.1 633198 633890 D similar to cell division ATP-binding protein [Streptococcus pyogenes MGAS5005]; cell division ATP-binding protein 633198..633890 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111306 YP_002996380.1 CDS ftsX NC_012891.1 633883 634812 D similar to cell-division protein [Streptococcus pyogenes MGAS8232]; cell-division protein 633883..634812 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111915 YP_002996381.1 CDS SDEG_0665 NC_012891.1 634935 635582 R similar to Zn-dependenthydrolase including glyoxylases [Streptococcus suis05ZYH33]; hydroxyacylglutathione hydrolase complement(634935..635582) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111978 YP_002996382.1 CDS dinG NC_012891.1 635811 638273 D unwinds DNA; bifunctional ATP-dependent DNA helicase/DNA polymerase III subunit epsilon 635811..638273 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112252 YP_002996383.1 CDS aspC NC_012891.1 638555 639751 D catalyzes the formation of oxalozcetate and L-glutamate from L-aspartate and 2-oxoglutarate; aspartate aminotransferase 638555..639751 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111673 YP_002996384.1 CDS asnC NC_012891.1 639789 641135 D catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; asparaginyl-tRNA synthetase 639789..641135 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112351 YP_002996385.1 CDS SDEG_0669 NC_012891.1 641426 642169 D similar to hypothetical protein SMU.1307c [Streptococcus mutans UA159]; hypothetical protein 641426..642169 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112350 YP_002996386.1 CDS SDEG_0670 NC_012891.1 642302 643192 D similar to P-loop ATPase protein family protein [Streptococcus pyogenes str. Manfredo]; hypothetical protein 642302..643192 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112253 YP_002996387.1 CDS SDEG_0671 NC_012891.1 643189 644166 D similar to transporter [Streptococcus pyogenes MGAS5005]; transporter 643189..644166 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112254 YP_002996388.1 CDS SDEG_0672 NC_012891.1 644163 645074 D similar to hypothetical cytosolic protein [Streptococcus pyogenes MGAS5005]; hypothetical protein 644163..645074 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112255 YP_002996389.1 CDS pepD NC_012891.1 645207 646604 D similar to dipeptidase [Streptococcus pyogenes MGAS5005]; dipeptidase 645207..646604 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112256 YP_002996390.1 CDS znuA NC_012891.1 646755 648302 D similar to high-affinity zinc uptake system protein znuA precursor [Streptococcus pyogenes MGAS5005]; high-affinity zinc uptake system protein znuA 646755..648302 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111275 YP_002996391.1 CDS SDEG_0675 NC_012891.1 648451 649182 D similar to transcriptional regulatorGntR family [Streptococcus pyogenes MGAS10750]; GntR family transcriptional regulator 648451..649182 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111972 YP_002996392.1 CDS agaS NC_012891.1 649202 650380 D similar to galactosamine-6-phosphate deaminase (isomerizing) [Streptococcus pyogenes MGAS5005]; galactosamine-6-phosphate deaminase 649202..650380 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112257 YP_002996393.1 CDS lacD.1 NC_012891.1 650390 651199 D similar to tagatose1,6-diphosphate aldolase [Streptococcus pyogenes MGAS5005]; tagatose1,6-diphosphate aldolase 650390..651199 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112315 YP_002996394.1 CDS SDEG_0678 NC_012891.1 651449 652162 R similar to transcriptional regulator [Streptococcus suis05ZYH33]; GntR family transcriptional regulator complement(651449..652162) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110885 YP_002996395.1 CDS bga NC_012891.1 652283 654067 D similar to beta-galactosidase [Streptococcus suis89/1591]; beta-galactosidase 652283..654067 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112258 YP_002996396.1 CDS SDEG_0680 NC_012891.1 654064 654549 D similar to PTS systemmannose/fructose IIB component [Streptococcus equi subsp. zooepidemicus MGCS10565]; PTS system mannose/fructose transporter subunit IIB 654064..654549 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112370 YP_002996397.1 CDS SDEG_0681 NC_012891.1 654592 655494 D similar to PTS system IIC component [Streptococcus pneumoniae TIGR4]; PTS system mannose/fructose transporter subunit IIC 654592..655494 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112259 YP_002996398.1 CDS SDEG_0682 NC_012891.1 655481 656296 D similar to phosphotransferase system, mannose/fructose /N-acetylgalactosamine-specific component IID [Streptococcus suis 05ZYH33]; phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IID 655481..656296 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112260 YP_002996399.1 CDS SDEG_0683 NC_012891.1 656296 656700 D similar to PTS system fructosesubfamily IIA component [Streptococcus suis 89/1591]; PTS system mannose/fructose transporter subunit IIAB 656296..656700 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112261 YP_002996400.1 CDS rpmE2 NC_012891.1 656911 657171 R RpmE2; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster do not have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome; 50S ribosomal protein L31 complement(656911..657171) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112262 YP_002996401.1 CDS SDEG_0685 NC_012891.1 657437 657694 D similar to transposase [Streptococcus pyogenes MGAS8232]; transposase 657437..657694 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111082 YP_002996402.1 CDS SDEG_0686 NC_012891.1 657702 658391 D similar to transposase [Streptococcus pyogenes MGAS10394]; transposase 657702..658391 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112263 YP_002996403.1 CDS SDEG_0687 NC_012891.1 658461 658640 D similar to transposase [Streptococcus pyogenes SSI-1]; transposase 658461..658640 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112264 YP_002996404.1 CDS SDEG_0688 NC_012891.1 658743 659447 D similar to transposase [Streptococcus pyogenes MGAS10270]; transposase 658743..659447 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112265 YP_002996405.1 CDS SDEG_0689 NC_012891.1 659550 660491 R similar to phosphoesterase DHH family protein [Streptococcus pyogenes MGAS10394]; phosphoesterase, DHH family protein complement(659550..660491) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112266 YP_002996406.1 CDS SDEG_0690 NC_012891.1 660497 660928 R similar to GCN5-related N-acetyltransferase [Actinobacillus succinogenes 130Z]; acetyltransferase complement(660497..660928) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112267 YP_002996407.1 CDS SDEG_0691 NC_012891.1 661013 661792 R similar to glutathione S-transferase family [Streptococcus thermophilus LMG 18311]; glutathione S-transferase complement(661013..661792) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112268 YP_002996408.1 CDS add NC_012891.1 662043 663062 D similar to adenosine deaminase [Streptococcus thermophilus LMG 18311]; adenosine deaminase 662043..663062 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112269 YP_002996409.1 CDS SDEG_0693 NC_012891.1 663130 663579 D An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group; flavodoxin 663130..663579 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112310 YP_002996410.1 CDS cm NC_012891.1 663755 664039 D similar to hypothetical protein spyM18 0789 [StreptococcuspyogenesMGAS8232]; hypothetical protein 663755..664039 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112270 YP_002996411.1 CDS SDEG_0695 NC_012891.1 664032 665294 D similar to chloride channel protein [Streptococcus pyogenesMGAS5005]; chloride channel protein 664032..665294 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111626 YP_002996412.1 CDS rplS NC_012891.1 665409 665756 D this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site; 50S ribosomal protein L19 665409..665756 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112271 YP_002996413.1 CDS ftsW NC_012891.1 666378 667589 D similar to cell division protein FtsW [Streptococcus equi subsp. zooepidemicus MGCS10565]; cell division protein FtsW 666378..667589 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112272 YP_002996414.1 CDS SDEG_0699 NC_012891.1 667682 668251 D similar to DNA gyrase related protein [Streptococcus pyogenes MGAS10394]; DNA gyrase subunit B 667682..668251 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111977 YP_002996415.1 CDS gyrB NC_012891.1 668252 670204 D negatively supercoils closed circular double-stranded DNA; DNA gyrase subunit B 668252..670204 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112273 YP_002996416.1 CDS SDEG_0701 NC_012891.1 670554 672278 D acts to negatively regulates ftsZ ring formation by modulating the frequency and position of the ftsZ ring formation; septation ring formation regulator EzrA 670554..672278 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112026 YP_002996417.1 CDS serB NC_012891.1 672411 673079 D similar to phosphoserine phosphatase [Streptococcus thermophilus LMG 18311]; phosphoserine phosphatase 672411..673079 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112274 YP_002996418.1 CDS SDEG_0703 NC_012891.1 673106 673561 R similar to hypothetical cytosolic protein [Streptococcus pyogenes MGAS10394]; hypothetical protein complement(673106..673561) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110481 YP_002996419.1 CDS eno NC_012891.1 673786 675093 D enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis; phosphopyruvate hydratase 673786..675093 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112275 YP_002996420.1 CDS sagA NC_012891.1 675793 675954 D similar to bacteriocin-like prepropeptide[Streptococcus dysgalactia subsp. equisimilis]; streptolysin S; bacteriocin-like prepropeptide 675793..675954 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111871 YP_002996421.1 CDS sagB NC_012891.1 676173 677123 D similar to SagB [Streptococcus dysgalactiae subsp. equisimilis]; streptolysin S biosynthesis protein 676173..677123 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110453 YP_002996422.1 CDS sagC NC_012891.1 677120 678184 D similar to streptolysin S biosynthesis protein [Streptococcus pyogenes MGAS5005]; streptolysin S biosynthesis protein 677120..678184 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110454 YP_002996423.1 CDS sagD NC_012891.1 678197 679555 D similar to streptolysin Sbiosynthesis protein SagD [Streptococcus pyogenesMGAS10270]; streptolysin S biosynthesis protein 678197..679555 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110455 YP_002996424.1 CDS sagE NC_012891.1 679530 680204 D similar to streptolysin S self-immunity protein [Streptococcus pyogenes MGAS5005]; streptolysin S self-immunity protein 679530..680204 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110456 YP_002996425.1 CDS sagF NC_012891.1 680201 680887 D similar to streptolysin S biosynthesis protein SagF [Streptococcus pyogenes MGAS10270]; streptolysin S biosynthesis protein 680201..680887 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110457 YP_002996426.1 CDS sagG NC_012891.1 680908 681831 D similar to streptolysin S export ATP-binding protein [Streptococcus pyogenes MGAS5005]; streptolysin S export ATP-binding protein 680908..681831 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110458 YP_002996427.1 CDS sagH NC_012891.1 681840 682967 D similar to streptolysin S export transmembrane protein [Streptococcus pyogenes MGAS6180]; streptolysin S export transmembrane protein 681840..682967 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110459 YP_002996428.1 CDS sagI NC_012891.1 682964 684082 D similar to streptolysin S export transmembrane protein [Streptococcus pyogenes MGAS5005]; streptolysin S export transmembrane protein 682964..684082 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110460 YP_002996429.1 CDS SDEG_0714 NC_012891.1 684437 687262 D similar to endonuclease/exonuclease /phosphatase family protein[Streptococcus pyogenes MGAS9429]; extracellular nuclease 684437..687262 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110461 YP_002996430.1 CDS SDEG_0715 NC_012891.1 687593 688096 D similar to hypothetical membrane spanning protein [Streptococcus pyogenes MGAS6180]; hypothetical protein 687593..688096 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112276 YP_002996431.1 CDS ligA NC_012891.1 688243 690201 D this protein catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction; essential for DNA replication and repair of damaged DNA; similar to ligase LigB; NAD-dependent DNA ligase LigA 688243..690201 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112277 YP_002996432.1 CDS SDEG_0717 NC_012891.1 690214 691236 D similar to YegS from E. coli; lipid kinase 690214..691236 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110895 YP_002996433.1 CDS pulA NC_012891.1 691242 693545 D pullulanase; similar to glycogen branching enzyme [Streptococcus mutans UA159]; glycogen debranching protein 691242..693545 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112278 YP_002996434.1 CDS glgB NC_012891.1 693652 695532 D catalyzes the transfer of a segment of a 1,4-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain; glycogen branching protein 693652..695532 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111328 YP_002996435.1 CDS glgC NC_012891.1 695671 696798 D catalyzes the formation of ADP-glucose and diphosphate from ATP and alpha-D-glucose 1-phosphate; glucose-1-phosphate adenylyltransferase 695671..696798 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111997 YP_002996436.1 CDS glgC NC_012891.1 696788 697921 D similar to glucose-1-phosphate adenylyltransferase GlgC [Streptococcus equi subsp. zooepidemicus MGCS10565]; glucose-1-phosphate adenylyltransferase 696788..697921 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111998 YP_002996437.1 CDS glgA NC_012891.1 697918 699357 D catalyzes the formation of alpha-1,4-glucan chains from ADP-glucose; glycogen synthase 697918..699357 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111999 YP_002996438.1 CDS atpE NC_012891.1 699622 699819 D produces ATP from ADP in the presence of a proton gradient across the membrane; subunit C is part of the membrane proton channel F0; F0F1 ATP synthase subunit C 699622..699819 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111996 YP_002996439.1 CDS atpB NC_012891.1 699854 700570 D Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0; F0F1 ATP synthase subunit A 699854..700570 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112361 YP_002996440.1 CDS atpF NC_012891.1 700588 701082 D Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit B is part of the membrane proton channel.; F0F1 ATP synthase subunit B 700588..701082 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112358 YP_002996441.1 CDS atpH NC_012891.1 701082 701618 D Produces ATP from ADP in the presence of a proton gradient across the membrane; the delta subunit is part of the catalytic core of the ATP synthase complex; F0F1 ATP synthase subunit delta 701082..701618 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112362 YP_002996442.1 CDS atpA NC_012891.1 701634 703139 D produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit; F0F1 ATP synthase subunit alpha 701634..703139 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112364 YP_002996443.1 CDS atpG NC_012891.1 703158 704033 D Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is a regulatory subunit; F0F1 ATP synthase subunit gamma 703158..704033 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112357 YP_002996444.1 CDS atpD NC_012891.1 704196 705602 D Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit; F0F1 ATP synthase subunit beta 704196..705602 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112363 YP_002996445.1 CDS atpC NC_012891.1 705615 706031 D part of catalytic core of ATP synthase; alpha(3)beta(3)gamma(1)delta(1)epsilon(1); involved in producing ATP from ADP in the presence of the proton motive force across the membrane; F0F1 ATP synthase subunit epsilon 705615..706031 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112360 YP_002996446.1 CDS murA NC_012891.1 706661 707932 D adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active; UDP-N-acetylglucosamine 1-carboxyvinyltransferase 706661..707932 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112359 YP_002996447.1 CDS endA NC_012891.1 708160 709026 D similar to DNA-entry nuclease [Streptococcus pyogenes MGAS10394]; DNA-entry nuclease 708160..709026 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111682 YP_002996448.1 CDS pheS NC_012891.1 709309 710352 D catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily; phenylalanyl-tRNA synthetase subunit alpha 709309..710352 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111869 YP_002996449.1 CDS pheT NC_012891.1 710547 712967 D catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily; phenylalanyl-tRNA synthetase subunit beta 710547..712967 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111290 YP_002996450.1 CDS SDEG_0735 NC_012891.1 713041 713454 D similar to salt-stress induced protein [Streptococcus pyogenes MGAS10750]; salt-stress induced protein 713041..713454 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111291 YP_002996451.1 CDS SDEG_0736 NC_012891.1 713447 713683 D similar to hypothetical protein MGAS10750 Spy0675 [Streptococcus pyogenes MGAS10750]; hypothetical protein 713447..713683 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112279 YP_002996452.1 CDS SDEG_0737 NC_012891.1 713662 713832 D similar to hypothetical protein spyM18 0830 [Streptococcus pyogenes MGAS8232]; hypothetical protein 713662..713832 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112280 YP_002996453.1 CDS SDEG_0738 NC_012891.1 713905 714981 D similar to ABC transporter permease protein [Streptococcus pyogenes MGAS10270]; ABC transporter permease 713905..714981 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112281 YP_002996454.1 CDS SDEG_0739 NC_012891.1 714988 715659 D similar to ABC transporter ATP-binding protein [Streptococcus pyogenes MGAS6180]; ABC transporter ATP-binding protein 714988..715659 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112282 YP_002996455.1 CDS SDEG_0740 NC_012891.1 715753 716664 R similar to neutral zinc metallopeptidase family [Streptococcus pyogenes MGAS10394]; neutral zinc metallopeptidase family complement(715753..716664) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112283 YP_002996456.1 CDS rexB NC_012891.1 716839 720063 D similar to ATP-dependent nuclease subunit B [Streptococcus pyogenes MGAS5005]; ATP-dependent nuclease subunit B 716839..720063 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112284 YP_002996457.1 CDS rexA NC_012891.1 720060 723692 D similar to ATP-dependent nuclease subunit A [Streptococcus pyogenes MGAS10394]; ATP-dependent nuclease subunit A 720060..723692 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111044 YP_002996458.1 CDS aspC NC_012891.1 723849 724967 D associated with arginine deiminase pathway genes; probably functions in arginine catabolism; transaminase 723849..724967 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111043 YP_002996459.1 CDS SDEG_0744 NC_012891.1 725089 725847 D similar to arginine-binding protein [Streptococcus pyogenes MGAS2096]; arginine-binding protein 725089..725847 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112352 YP_002996460.1 CDS rpsU NC_012891.1 725937 726113 D a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA; 30S ribosomal protein S21 725937..726113 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112285 YP_002996461.1 CDS mscL NC_012891.1 726243 726617 R similar to large-conductance mechanosensitive channel [Streptococcus pyogenes MGAS5005]; large-conductance mechanosensitive channel complement(726243..726617) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110449 YP_002996462.1 CDS dnaG NC_012891.1 726745 728559 D synthesizes RNA primers at the replication forks; DNA primase 726745..728559 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110942 YP_002996463.1 CDS rpoD NC_012891.1 728568 729677 D sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; primary sigma factor of bacterium; RNA polymerase sigma factor RpoD 728568..729677 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111846 YP_002996464.1 CDS SDEG_0749 NC_012891.1 730002 730340 D similar to hypothetical cytosolic protein [Streptococcus pyogenes MGAS5005]; hypothetical protein 730002..730340 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111092 YP_002996465.1 CDS SDEG_0750 NC_012891.1 730473 731327 D similar to dTDP-4-dehydrorhamnose reductase [Streptococcus pyogenes MGAS10394]; dTDP-4-dehydrorhamnose reductase 730473..731327 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112286 YP_002996466.1 CDS rgpAc NC_012891.1 731446 732600 D similar to alpha-(1,2)- rhamnosyltransferase[Streptococcus pyogenes MGAS5005]; alpha-(1,2)-rhamnosyltransferase 731446..732600 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112287 YP_002996467.1 CDS rgpBc NC_012891.1 732590 733522 D similar to alpha-L-Rhaalpha-13-L- rhamnosyltransferase[Streptococcus pyogenes MGAS5005]; alpha-L-Rhaalpha-1,3-L-rhamnosyltransferase 732590..733522 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111046 YP_002996468.1 CDS rgpC NC_012891.1 733525 734331 D similar to polysaccharide ABC exporter membrane-spanning protein [Streptococcus thermophilus LMG 18311]; polysaccharide ABC exporter membrane-spanning protein 733525..734331 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111047 YP_002996469.1 CDS SDEG_0754 NC_012891.1 734331 735497 D similar to ABC-type polysaccharide/polyolphosphatetransport system ATPase component [Streptococcus thermophilus LMD-9]; polysaccharide/polyolphosphate ABC transporter ATPase 734331..735497 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111048 YP_002996470.1 CDS SDEG_0755 NC_012891.1 735510 736793 D similar to glycosyl transferase family protein [Anabaena variabilis ATCC29413]; hypothetical protein 735510..736793 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112288 YP_002996471.1 CDS wbbX NC_012891.1 736808 738034 D similar to glycosyl transferase [Leifsonia xyli subsp. xyli str. CTCB07]; hypothetical protein 736808..738034 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112289 YP_002996472.1 CDS SDEG_0757 NC_012891.1 738027 739010 D similar to rhamnosyltransferase [Leifsonia xyli subsp. xyli str. CTCB07]; rhamnosyltransferase 738027..739010 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111951 YP_002996473.1 CDS SDEG_0758 NC_012891.1 739020 740501 D similar to hypothetical protein str1466 [Streptococcus thermophilus CNRZ1066]; hypothetical protein 739020..740501 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112290 YP_002996474.1 CDS SDEG_0759 NC_012891.1 740546 741355 D similar to glycosyltransferase involved in cell wall biogenesis [Streptococcus thermophilus LMD-9]; cell wall biosynthesis glycosyltransferase 740546..741355 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112291 YP_002996475.1 CDS SDEG_0760 NC_012891.1 741352 742047 D similar to glycosyltransferase [Streptococcus equi subsp. zooepidemicus MGCS10565]; glycosyltransferase 741352..742047 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112292 YP_002996476.1 CDS SDEG_0761 NC_012891.1 742048 742404 D lytic transglycosylase, dTDP-4-rhamnose reductase; similar to glycosyltransferase lytictransglycosylase dTDP-4-rhamnosereductase[Streptococcus equi subsp. zooepidemicus MGCS10565]; glycosyltransferase 742048..742404 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112293 YP_002996477.1 CDS SDEG_0762 NC_012891.1 742467 744938 D similar to phosphoglycerol transferase [Streptococcusequi subsp. zooepidemicusMGCS10565]; phosphoglycerol transferase 742467..744938 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112294 YP_002996478.1 CDS galE NC_012891.1 745121 746137 D similar to UDP-glucose 4-epimerase GalE [Streptococcus equi subsp. zooepidemicus MGCS10565]; UDP-glucose 4-epimerase 745121..746137 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112295 YP_002996479.1 CDS amrA NC_012891.1 746258 747511 D similar to AmrA [Streptococcus pyogenes MGAS10394]; transcriptional activator 746258..747511 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111983 YP_002996480.1 CDS pepT NC_012891.1 747691 748914 D catalyzes the release of the N-terminal amino acid from a tripeptide; peptidase T 747691..748914 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112322 YP_002996481.1 CDS ebsA NC_012891.1 748958 749446 D similar to pore forming protein EbsA [Streptococcus pyogenes MGAS10750]; pore forming protein 748958..749446 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111280 YP_002996482.1 CDS SDEG_0767 NC_012891.1 749433 749630 R similar to ferredoxin [Streptococcus pyogenes MGAS10750]; ferredoxin complement(749433..749630) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111863 YP_002996483.1 CDS SDEG_0768 NC_012891.1 749678 750157 D similar to hypothetical protein SPs1318 [Streptococcus pyogenes SSI-1]; hypothetical protein 749678..750157 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112296 YP_002996484.1 CDS cmk NC_012891.1 750172 750852 D Catalyzes the formation of (d)CDP from ATP and (d)CMP; cytidylate kinase 750172..750852 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112297 YP_002996485.1 CDS infC NC_012891.1 751014 751544 D IF-3 has several functions that are required and promote translation initiation including; preventing association of 70S by binding to 30S; monitoring codon-anticodon interactions by promoting disassociation of fMet-tRNA(fMet) from initiation complexes formed on leaderless mRNAs or incorrectly bound noninitiatior tRNAs and complexes with noncanonical start sites; stimulates codon-anticodon interactions at P-site; involved in moving mRNA to the P-site; and in recycling subunits; translation initiation factor IF-3 751014..751544 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111627 YP_002996486.1 CDS rpmI NC_012891.1 751585 751782 D similar to 50S ribosomal protein L35 [Streptococcus pyogenes MGAS8232]; 50S ribosomal protein L35 751585..751782 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112053 YP_002996487.1 CDS rplT NC_012891.1 751841 752200 D binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit; 50S ribosomal protein L20 751841..752200 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111087 YP_002996488.1 CDS SDEG_0773 NC_012891.1 752485 754713 R similar to phosphoglycerol transferase [Streptococcus pyogenes MGAS10394]; phosphoglycerol transferase complement(752485..754713) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111073 YP_002996489.1 CDS SDEG_0774 NC_012891.1 754815 755978 D similar to methyltransferase [Streptococcus pyogenes MGAS5005]; methyltransferase 754815..755978 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110367 YP_002996490.1 CDS aroD NC_012891.1 755975 756661 D catalyzes the dehydration of 3-dehydroquinate to form 3-dehydroshikimate in aromatic amino acid biosynthesis; 3-dehydroquinate dehydratase 755975..756661 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110368 YP_002996491.1 CDS aroF NC_012891.1 756759 757925 D catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis; chorismate synthase 756759..757925 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112340 YP_002996492.1 CDS SDEG_0777 NC_012891.1 757987 758328 D similar to hypothetical cytosolic protein [Streptococcus pyogenes MGAS10750]; hypothetical protein 757987..758328 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112342 YP_002996493.1 CDS gor NC_012891.1 758541 759902 D catalyzes the reduction of 2 glutathione to glutathione disulfide; maintains high levels of reduced glutathione in the cytosol; involved in redox regulation and oxidative defense; glutathione reductase 758541..759902 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110369 YP_002996494.1 CDS SDEG_0779 NC_012891.1 759990 761261 R similar to dihydrofolate synthase [Streptococcus pyogenes MGAS10394]; dihydrofolate synthase complement(759990..761261) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112016 YP_002996495.1 CDS SDEG_0780 NC_012891.1 761309 761749 R similar to hypothetical protein spyM18 0877 [Streptococcus pyogenes MGAS8232]; hypothetical protein complement(761309..761749) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110370 YP_002996496.1 CDS nifS1 NC_012891.1 761985 763127 D similar to cysteine desulfurase / selenocysteine lyase [Streptococcus pyogenes MGAS10270]; cysteine desulfurase/selenocysteine lyase 761985..763127 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110371 YP_002996497.1 CDS thiI NC_012891.1 763129 764343 D Required for the synthesis of the thiazole moiety; thiamine biosynthesis protein ThiI 763129..764343 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111711 YP_002996498.1 CDS capA NC_012891.1 764522 765676 D similar to capsule biosynthesis protein [Streptococcus pyogenes MGAS5005]; capsule biosynthesis protein 764522..765676 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110517 YP_002996499.1 CDS SDEG_0784 NC_012891.1 765790 766818 D similar to transposase [Streptococcus pyogenes MGAS10270]; transposase 765790..766818 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111601 YP_002996500.1 CDS rplU NC_012891.1 766922 767341 R similar to ribosomal protein L21 [Streptococcus agalactiae CJB111]; 50S ribosomal protein L21 complement(766922..767341) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110372 YP_002996501.1 CDS rplU NC_012891.1 767066 767380 D similar to 50S ribosomal protein L21 [Streptococcus pyogenes MGAS5005]; 50S ribosomal protein L21 767066..767380 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111074 YP_002996502.1 CDS SDEG_0787 NC_012891.1 767392 767718 D similar to hypothetical protein spyM18 0884 [Streptococcus pyogenes MGAS8232]; hypothetical protein 767392..767718 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111075 YP_002996503.1 CDS rpmA NC_012891.1 767746 768039 D involved in the peptidyltransferase reaction during translation; 50S ribosomal protein L27 767746..768039 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110373 YP_002996504.1 CDS SDEG_0789 NC_012891.1 768287 769201 D similar to transcriptional regulator; LysR family transcriptional regulator 768287..769201 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111079 YP_002996505.1 CDS lsp NC_012891.1 769198 769656 D lipoprotein signal peptidase; integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis; lipoprotein signal peptidase 769198..769656 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110374 YP_002996506.1 CDS SDEG_0791 NC_012891.1 769646 770539 D similar to ribosomal large subunit pseudouridine synthase D [Streptococcus pyogenes MGAS5005]; ribosomal large subunit pseudouridine synthase D 769646..770539 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110911 YP_002996507.1 CDS SDEG_0792 NC_012891.1 770666 771340 R similar to membrane-associated alkaline phosphatase [Streptococcus equi subsp. zooepidemicus MGCS10565]; membrane-associated alkaline phosphatase complement(770666..771340) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110375 YP_002996508.1 CDS pyrR NC_012891.1 771559 772080 D regulates pyrimidine biosynthesis by binding to the mRNA of the pyr genes, also has been shown to have uracil phosphoribosyltransferase activity; bifunctional pyrimidine regulatory protein PyrR/uracil phosphoribosyltransferase 771559..772080 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110376 YP_002996509.1 CDS pyrP NC_012891.1 772096 773355 D similar to uracil permease [Streptococcus pyogenes MGAS10270]; uracil permease 772096..773355 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111346 YP_002996510.1 CDS carA NC_012891.1 774383 775474 D catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers; carbamoyl phosphate synthase small subunit 774383..775474 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111338 YP_002996511.1 CDS carB NC_012891.1 775726 778902 D four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate; CarB is responsible for the amidotransferase activity; carbamoyl phosphate synthase large subunit 775726..778902 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111602 YP_002996512.1 CDS SDEG_0798 NC_012891.1 779124 780386 D similar to periplasmic component of efflux system [Streptococcus pyogenes MGAS10750]; periplasmic protein of efflux system 779124..780386 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111603 YP_002996513.1 CDS SDEG_0799 NC_012891.1 780386 781096 D similar to ABC transporter ATP-binding protein [Streptococcus pyogenes MGAS6180]; ABC transporter ATP-binding protein 780386..781096 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110377 YP_002996514.1 CDS SDEG_0800 NC_012891.1 781108 782328 D similar to ABC transporter permease protein [Streptococcus pyogenes MGAS5005]; ABC transporter permease 781108..782328 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110378 YP_002996515.1 CDS SDEG_0801 NC_012891.1 782321 782938 D similar to hypothetical protein Sez 1119 [Streptococcus equi subsp. zooepidemicus MGCS10565]; hypothetical protein 782321..782938 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110379 YP_002996516.1 CDS SDEG_0802 NC_012891.1 783013 784755 D similar to glycerophosphoryl diester phosphodiesterase [Streptococcus pyogenes MGAS6180]; glycerophosphoryl diester phosphodiesterase 783013..784755 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110380 YP_002996517.1 CDS rpsP NC_012891.1 784873 785154 D binds to lower part of 30S body where it stabilizes two domains; required for efficient assembly of 30S; in Escherichia coli this protein has nuclease activity; 30S ribosomal protein S16 784873..785154 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110381 YP_002996518.1 CDS SDEG_0804 NC_012891.1 785164 785403 D similar to hypothetical protein spyM18 0901 [Streptococcus pyogenes MGAS8232]; hypothetical protein 785164..785403 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111108 YP_002996519.1 CDS SDEG_0805 NC_012891.1 785669 787126 D similar to cell wall surface anchor family protein [Streptococcus equi subsp. zooepidemicus MGCS10565]; cell wall surface anchor family protein 785669..787126 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110382 YP_002996520.1 CDS rimM NC_012891.1 787495 788013 D Essential for efficient processing of 16S rRNA; 16S rRNA-processing protein RimM 787495..788013 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110383 YP_002996521.1 CDS trmD NC_012891.1 788003 788734 D methylates guanosine-37 in various tRNAs; uses S-adenosyl-L-methionine to transfer methyl group to tRNA; tRNA (guanine-N(1)-)-methyltransferase 788003..788734 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111050 YP_002996522.1 CDS trxB NC_012891.1 788734 789726 D similar to thioredoxin reductase [Streptococcus pyogenes MGAS5005]; thioredoxin reductase 788734..789726 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111926 YP_002996523.1 CDS SDEG_0809 NC_012891.1 789915 790973 D similar to regulatory protein [Streptococcus pyogenes MGAS5005]; regulatory protein 789915..790973 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111934 YP_002996524.1 CDS apbA NC_012891.1 790986 791909 D ketopantoate reductase; catalyzes the NADPH reduction of ketopantoate to pantoate; functions in pantothenate (vitamin B5) biosynthesis; 2-dehydropantoate 2-reductase 790986..791909 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110384 YP_002996525.1 CDS SDEG_0811 NC_012891.1 792144 792857 D similar to DeoR family regulatory protein [Streptococcus pyogenes str. Manfredo]; fructose repressor 792144..792857 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112327 YP_002996526.1 CDS fruB NC_012891.1 792854 793765 D similar to 1-phosphofructokinase [Streptococcus pyogenes MGAS10270]; 1-phosphofructokinase 792854..793765 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110385 YP_002996527.1 CDS fruA NC_012891.1 793762 795708 D similar to PTS system fructose-specific II ABC component [Streptococcus pyogenes MGAS2096]; PTS system fructose-specific transporter subunit IIABC 793762..795708 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111911 YP_002996528.1 CDS mur1-1 NC_012891.1 795790 796398 D similar to autolysin [Streptococcus pyogenes MGAS5005]; autolysin 795790..796398 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111910 YP_002996529.1 CDS mur1-2 NC_012891.1 796558 797265 D similar to N-acetylmuramidase [Streptococcus pyogenes MGAS10270]; N-acetylmuramidase 796558..797265 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111680 YP_002996530.1 CDS SDEG_0816 NC_012891.1 797316 797837 D similar to hypothetical protein SAG1344 [Streptococcus agalactiae 2603V/R]; hypothetical protein 797316..797837 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111681 YP_002996531.1 CDS SDEG_0817 NC_012891.1 797876 798289 D similar to transposase [Streptococcus pyogenes MGAS10394]; transposase 797876..798289 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110386 YP_002996532.1 CDS SDEG_0818 NC_012891.1 798289 799137 D similar to DegV family protein [Streptococcus pyogenes MGAS10750]; DegV family protein 798289..799137 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110387 YP_002996533.1 CDS papS NC_012891.1 799257 800465 D catalyzes the addition and repair of the 3'-terminal CCA sequence in tRNA; these proteins belong to the CCA-adding enzyme subfamily 2 which does not have phosphohydrolase activity; tRNA CCA-pyrophosphorylase 799257..800465 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110388 YP_002996534.1 CDS SDEG_0820 NC_012891.1 800462 802339 D similar to ABC transporter ATP-binding protein uup [Streptococcus pyogenes MGAS5005]; ABC transporter ATP-binding protein 800462..802339 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111750 YP_002996535.1 CDS SDEG_0821 NC_012891.1 802447 804192 D similar to ABC transporter ATP-binding /permease protein [Streptococcus equi subsp. zooepidemicus MGCS10565]; ABC transporter ATP-binding protein/permease 802447..804192 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110389 YP_002996536.1 CDS SDEG_0822 NC_012891.1 804192 805964 D similar to ABC transporter ATP-binding /permease protein [Streptococcusequi subsp.zooepidemicus MGCS10565]; ABC transporter ATP-binding protein/permease 804192..805964 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110390 YP_002996537.1 CDS gdh NC_012891.1 806154 807503 D converts 2-oxoglutarate to glutamate; in Escherichia coli this enzyme plays a role in glutamate synthesis when the cell is under energy restriction; uses NADPH; forms a homohexamer; glutamate dehydrogenase 806154..807503 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110391 YP_002996538.1 CDS fms NC_012891.1 807628 808038 D cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+); peptide deformylase 807628..808038 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111990 YP_002996539.1 CDS SDEG_0825 NC_012891.1 808226 810250 R similar to cell surface 5'-nucleotidase [Streptococcus equi subsp. zooepidemicus MGCS10565]; cell surface 5'-nucleotidase complement(808226..810250) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111899 YP_002996540.1 CDS SDEG_0826 NC_012891.1 810469 810927 D similar to GTP pyrophosphokinase [Streptococcus pyogenes MGAS5005]; GTP pyrophosphokinase 810469..810927 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110392 YP_002996541.1 CDS SDEG_0827 NC_012891.1 810930 811118 D similar to GTP pyrophosphokinase [Streptococcus pyogenes MGAS10750]; GTP pyrophosphokinase 810930..811118 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110393 YP_002996542.1 CDS sptR NC_012891.1 811121 811789 D similar to two-component response regulator [Streptococcus pyogenes MGAS5005]; two-component response regulator 811121..811789 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110394 YP_002996543.1 CDS sptS NC_012891.1 811771 813030 D similar to two component system histidine kinase [Streptococcus pyogenes MGAS6180]; two component system histidine kinase 811771..813030 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110499 YP_002996544.1 CDS SDEG_0831 NC_012891.1 814533 816338 D similar to ABC-type multidrug transportsystem ATPas and permease component[Streptococcus suis 98HAH33]; ATPase and permease component 814533..816338 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110395 YP_002996545.1 CDS SDEG_0832 NC_012891.1 816340 818082 D similar to ABC transporter ATP-binding /permease protein [Streptococcus equi subsp. zooepidemicus MGCS10565]; ABC transporter ATP-binding protein/permease 816340..818082 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110396 YP_002996546.1 CDS mvaK1 NC_012891.1 818287 819165 D similar to mevalonate kinase [Streptococcus pyogenes MGAS10270]; mevalonate kinase 818287..819165 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110397 YP_002996547.1 CDS mvaD NC_012891.1 819147 820091 D similar to diphosphomevalonate decarboxylase [Streptococcus pyogenes MGAS10394]; diphosphomevalonate decarboxylase 819147..820091 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111700 YP_002996548.1 CDS mvaK2 NC_012891.1 820036 821097 D similar to phosphomevalonate kinase [Streptococcus pyogenes MGAS10270]; phosphomevalonate kinase 820036..821097 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111699 YP_002996549.1 CDS SDEG_0836 NC_012891.1 821084 822076 D catalyzes the isomerization of isopentenyl pyrophosphate to dimethylallyl diphosphate; isopentenyl pyrophosphate isomerase 821084..822076 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111701 YP_002996550.1 CDS SDEG_0837 NC_012891.1 822490 823749 R similar to transcriptional regulatorp utative [Streptococcus pneumoniae TIGR4]; transcriptional regulator complement(822490..823749) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110398 YP_002996551.1 CDS SDEG_0838 NC_012891.1 825449 826477 D similar to transposase [Streptococcus pyogenes MGAS10270]; transposase 825449..826477 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110399 YP_002996552.1 CDS SDEG_0839 NC_012891.1 826602 827531 D similar to hypothetical protein lin1204 [Listeria innocua Clip11262]; hypothetical protein 826602..827531 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110400 YP_002996553.1 CDS SDEG_0840 NC_012891.1 827723 828526 D similar to fibronectin-binding protein [Streptococcus equi subsp. zooepidemicus]; hypothetical protein 827723..828526 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110401 YP_002996554.1 CDS SDEG_0841 NC_012891.1 829360 830904 R similar to transcriptional regulator [Streptococcus pneumoniae TIGR4]; transcriptional regulator complement(829360..830904) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110402 YP_002996555.1 CDS mvaS1 NC_012891.1 831065 832342 R similar to HMG-CoA reductase [Streptococcus pyogenes MGAS8232]; HMG-CoA reductase complement(831065..832342) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110403 YP_002996556.1 CDS mvaS2 NC_012891.1 832323 833504 R similar to HMG-CoA synthase [Streptococcus pyogenes MGAS8232]; HMG-CoA synthase complement(832323..833504) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111702 YP_002996557.1 CDS SDEG_0844 NC_012891.1 833692 834720 R similar to transposase [Streptococcus pyogenes MGAS10270]; transposase complement(833692..834720) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111703 YP_002996558.1 CDS thyA NC_012891.1 834893 835738 D ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived; thymidylate synthase 834893..835738 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110404 YP_002996559.1 CDS dyr NC_012891.1 835819 836316 D similar to dihydrofolate reductase [Streptococcus pyogenes MGAS5005]; dihydrofolate reductase 835819..836316 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110522 YP_002996560.1 CDS SDEG_0847 NC_012891.1 836336 836506 D similar to hypothetical protein Sez 1076 [Streptococcus equisubsp. zooepidemicus MGCS10565]; hypothetical protein 836336..836506 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111862 YP_002996561.1 CDS clpX NC_012891.1 836620 837849 D binds and unfolds substrates as part of the ClpXP protease; ATP-dependent protease ATP-binding subunit ClpX 836620..837849 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110405 YP_002996562.1 CDS engB NC_012891.1 837859 838458 D binds guanine nucleotides; in Escherichia coli depletion results in defective cell division and filamentation; in Bacillus subtilis this gene is essential; ribosome biogenesis GTP-binding protein YsxC 837859..838458 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111625 YP_002996563.1 CDS SDEG_0850 NC_012891.1 838602 839345 D similar to hypothetical protein MGAS10270 Spy0751 [Streptococcus pyogenes MGAS10270]; hypothetical protein 838602..839345 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110406 YP_002996564.1 CDS clpL NC_012891.1 839402 841501 R similar to ATP-dependentprotease ATP-binding subunit ClpL [Streptococcus equi subsp.zooepidemicusMGCS10565]; ATP-dependentprotease ATP-binding subunit complement(839402..841501) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110407 YP_002996565.1 CDS SDEG_0852 NC_012891.1 841774 842637 R similar to transposase [Streptococcus pyogenes MGAS2096]; transposase complement(841774..842637) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111623 YP_002996566.1 CDS rplJ NC_012891.1 843825 844373 D binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit; 50S ribosomal protein L10 843825..844373 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110408 YP_002996567.1 CDS SDEG_0854 NC_012891.1 844419 844793 R similar to hypothetical protein spyM18 1050 [Streptococcus pyogenes MGAS8232]; hypothetical protein complement(844419..844793) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111065 YP_002996568.1 CDS rplL NC_012891.1 844423 844803 D present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulates GTPase activity of translation factors; 50S ribosomal protein L7/L12 844423..844803 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110409 YP_002996569.1 CDS SDEG_0856 NC_012891.1 845043 846278 D similar to DD-carboxypeptidase penicillin-binding protein [Streptococcus pyogenes MGAS8232]; carboxypeptidase, penicillin-binding protein 845043..846278 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111067 YP_002996570.1 CDS SDEG_0857 NC_012891.1 846369 847331 R similar to polysaccharide deacetylase [Streptococcus pyogenes MGAS2096]; polysaccharide deacetylase complement(846369..847331) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110410 YP_002996571.1 CDS SDEG_0858 NC_012891.1 847515 848801 D similar to homoserine dehydrogenase [Streptococcus suis 89/1591]; homoserine dehydrogenase 847515..848801 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110411 YP_002996572.1 CDS thrB NC_012891.1 848803 849663 D similar to homoserine kinase [Streptococcus pneumoniae D39]; homoserine kinase 848803..849663 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110412 YP_002996573.1 CDS folC1 NC_012891.1 849723 851045 D similar to folylpolyglutamate synthase / dihydrofolate synthase [Streptococcus pyogenes MGAS10270]; bifunctional folylpolyglutamate synthase/dihydrofolate synthase 849723..851045 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110520 YP_002996574.1 CDS folE NC_012891.1 851085 851651 D involved in the first step of tetrahydrofolate biosynthesis; catalyzes the formation of formate and 2-amino-4-hydroxy-6-(erythro-1,2, 3-trihydroxypropyl)dihydropteridine triphosphate from GTP and water; forms a homopolymer; GTP cyclohydrolase I 851085..851651 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111902 YP_002996575.1 CDS folP NC_012891.1 851661 852467 D similar to dihydropteroate synthase [Streptococcus pyogenes]; dihydropteroate synthase 851661..852467 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111903 YP_002996576.1 CDS folQ NC_012891.1 852475 852834 D similar to dihydroneopterin aldolase [Streptococcus pyogenes MGAS5005]; dihydroneopterin aldolase 852475..852834 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111905 YP_002996577.1 CDS folK NC_012891.1 852831 853331 D similar to hydroxymethylpterin pyrophosphokinase [Streptococcus pyogenes]; hydroxymethylpterin pyrophosphokinase 852831..853331 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111906 YP_002996578.1 CDS murB NC_012891.1 853480 854367 D catalyzes the reduction of UDP-N-acetylglucosamine enolpyruvate to form UDP-N-acetylmuramate in peptidoglycan biosynthesis; UDP-N-acetylenolpyruvoylglucosamine reductase 853480..854367 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111904 YP_002996579.1 CDS potA NC_012891.1 854416 855570 D similar to PotA [Streptococcus pyogenes MGAS10394]; spermidine/putrescine transport ATP-binding protein 854416..855570 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111683 YP_002996580.1 CDS potB NC_012891.1 855533 856348 D similar to PotB [Streptococcus pyogenes MGAS10394]; spermidine/putrescine transport system permease 855533..856348 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111298 YP_002996581.1 CDS potC NC_012891.1 856345 857121 D similar to spermidine/putrescine transport system permease protein [Streptococcus pyogenes MGAS5005]; spermidine/putrescine transport system permease 856345..857121 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111299 YP_002996582.1 CDS potD NC_012891.1 857114 858187 D similar to spermidine/putrescine extracellular binding protein [Streptococcus pyogenes str. Manfredo]; spermidine/putrescine extracellular binding protein 857114..858187 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111300 YP_002996583.1 CDS dpiA NC_012891.1 858241 858906 R similar to two-component response regulator [Streptococcus pyogenes MGAS8232]; two-component response regulator complement(858241..858906) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111301 YP_002996584.1 CDS dpiB NC_012891.1 858887 860131 R similar to sensor kinase dpiB [Streptococcus pyogenes MGAS10750]; two component system histidine kinase complement(858887..860131) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111853 YP_002996585.1 CDS malP NC_012891.1 860292 861623 D similar to L-malate permease [Streptococcus pyogenes MGAS315]; L-malate permease 860292..861623 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111854 YP_002996586.1 CDS SDEG_0873 NC_012891.1 861654 862820 D similar to NAD-dependent malic enzyme [Streptococcus pyogenes NZ131]; NAD-dependent malic enzyme 861654..862820 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110923 YP_002996587.1 CDS SDEG_0874 NC_012891.1 862952 864520 D similar to chloride channel protein [Streptococcus pyogenes MGAS2096]; chloride channel protein 862952..864520 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110413 YP_002996588.1 CDS SDEG_0875 NC_012891.1 864579 865502 R similar to hypothetical protein STRINF 01402 [Streptococcus infantarius subsp. infantarius ATCC BAA-102]; hypothetical protein complement(864579..865502) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110414 YP_002996589.1 CDS SDEG_0876 NC_012891.1 865722 866336 D similar to lipase /acylhydrolase family protein [Streptococcus pyogenes MGAS5005]; lipase/acylhydrolase 865722..866336 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110415 YP_002996590.1 CDS SDEG_0877 NC_012891.1 866513 867640 D similar to hypothetical protein SPy 1117 [Streptococcus pyogenes M1 GAS]; hypothetical protein 866513..867640 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110416 YP_002996591.1 CDS radC NC_012891.1 867688 868368 D Involved in DNA double-strand break repair and recombination. Promotes the annealing of complementary single-stranded DNA and by simulation of RAD51 recombinase; DNA repair protein RadC 867688..868368 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110417 YP_002996592.1 CDS SDEG_0879 NC_012891.1 868370 869065 R similar to glutamine amidotransferase classI [Streptococcus pyogenes MGAS5005]; glutamine amidotransferase, classI complement(868370..869065) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111349 YP_002996593.1 CDS rex NC_012891.1 869074 869718 R modulates transcription in response to the NADH/NAD(+) redox state; redox-sensing transcriptional repressor Rex complement(869074..869718) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110418 YP_002996594.1 CDS SDEG_0881 NC_012891.1 869896 870108 R similar to hypothetical protein stu1191 [Streptococcus thermophilus LMG 18311]; hypothetical protein complement(869896..870108) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111042 YP_002996595.1 CDS SDEG_0882 NC_012891.1 870176 870523 R similar to hypothetical protein Sez 1049 [Streptococcus equi subsp. zooepidemicus MGCS10565]; hypothetical protein complement(870176..870523) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110419 YP_002996596.1 CDS nifS2 NC_012891.1 870513 871640 R similar to cysteine desulfhydrase [Streptococcus pyogenes MGAS5005]; cysteine desulfhydrase complement(870513..871640) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110420 YP_002996597.1 CDS SDEG_0884 NC_012891.1 871637 872617 R catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP; ribose-phosphate pyrophosphokinase complement(871637..872617) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111712 YP_002996598.1 CDS SDEG_0885 NC_012891.1 872746 873327 R similar to adenylate cyclase family [Streptococcus pyogenes MGAS10394]; adenylate cyclase family complement(872746..873327) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110421 YP_002996599.1 CDS SDEG_0886 NC_012891.1 873421 874092 D similar to GTP pyrophosphokinase [Streptococcus pyogenes MGAS5005]; GTP pyrophosphokinase 873421..874092 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110422 YP_002996600.1 CDS ppnK NC_012891.1 874064 874903 D catalyzes the phosphorylation of NAD to NADP; inorganic polyphosphate/ATP-NAD kinase 874064..874903 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110423 YP_002996601.1 CDS SDEG_0888 NC_012891.1 874900 875805 D similar to ribosomal large subunit pseudouridine synthase D [Streptococcus pyogenes MGAS10394]; ribosomal large subunit pseudouridine synthase D 874900..875805 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111303 YP_002996602.1 CDS eutD NC_012891.1 875809 876804 D in Salmonella this enzyme is required for ethanolamine catabolism; has higher affinity for CoA than Pta; phosphotransacetylase 875809..876804 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110424 YP_002996603.1 CDS SDEG_0890 NC_012891.1 876913 877686 D similar to short chain dehydrogenase [Streptococcus pyogenes MGAS10394]; short chain dehydrogenase 876913..877686 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111321 YP_002996604.1 CDS SDEG_0891 NC_012891.1 877881 878570 R similar to Na+ driven multidrug efflux pump [Streptococcus pyogenes MGAS10270]; Na+ driven multidrug efflux pump complement(877881..878570) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110425 YP_002996605.1 CDS SDEG_0892 NC_012891.1 878990 879718 D similar to ABC transporter (ATP-binding protein) [Streptococcus pyogenes MGAS315]; ABC transporter 878990..879718 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110426 YP_002996606.1 CDS SDEG_0893 NC_012891.1 879711 881237 D similar to glycine betaine transport system permease protein [Streptococcus pyogenes MGAS5005]; glycine betaine transport system permease 879711..881237 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110427 YP_002996607.1 CDS guaC NC_012891.1 881515 882498 D similar to guanosine 5'-monophosphate oxidoreductase [Streptococcus pyogenes MGAS5005]; guanosine 5'-monophosphate oxidoreductase 881515..882498 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110428 YP_002996608.1 CDS xpt NC_012891.1 882803 883384 D Catalyzes the transfer of the phosphoribosyl moiety from 5-phospho--D-ribosyl-1-pyrophosphate (PRib-PP) to the 6-oxo-guanine and -xanthine; xanthine phosphoribosyltransferase 882803..883384 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112024 YP_002996609.1 CDS SDEG_0896 NC_012891.1 883384 884658 D similar to xanthine permease [Streptococcus pyogenes MGAS10270]; xanthine permease 883384..884658 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111953 YP_002996610.1 CDS apbE NC_012891.1 884787 885722 R similar to iron-sulfur cluster assembly /repair protein ApbE [Streptococcus pyogenes MGAS10270]; iron-sulfur cluster assembly/repair protein ApbE complement(884787..885722) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110429 YP_002996611.1 CDS SDEG_0898 NC_012891.1 885775 885960 R 4-OT; member of subfamily 5; forms a dimer; the function in the Escherichia coli cell is unknown; 4-oxalocrotonate tautomerase complement(885775..885960) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112328 YP_002996612.1 CDS tdk NC_012891.1 886157 886759 D similar to thymidine kinase Tdk [Streptococcus equi subsp. zooepidemicus MGCS10565]; thymidine kinase Tdk 886157..886759 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110430 YP_002996613.1 CDS prfA NC_012891.1 886782 887861 D recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2; peptide chain release factor 1 886782..887861 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110514 YP_002996614.1 CDS hemK NC_012891.1 887861 888700 D similar to peptide release factor-glutamine N5-methyltransferase [Streptococcus pyogenes MGAS5005]; peptide release factor-glutamine N5-methyltransferase 887861..888700 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111305 YP_002996615.1 CDS SDEG_0902 NC_012891.1 888648 889274 D similar to Sua5/YciO/YrdC/YwlC family protein [Streptococcus pyogenes MGAS10750]; Sua5/YciO/YrdC/YwlC family protein 888648..889274 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112028 YP_002996616.1 CDS SDEG_0903 NC_012891.1 889285 889722 D similar to COG0454, Histone acetyltransferase HPA2 and related acetyltransferases [Streptococcus pyogenes M49 591]; histone acetyltransferase HPA2-like protein 889285..889722 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110431 YP_002996617.1 CDS glyA NC_012891.1 889733 890989 D catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate; serine hydroxymethyltransferase 889733..890989 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110432 YP_002996618.1 CDS SDEG_0905 NC_012891.1 890996 891973 D similar to hypothetical protein M5005 Spy 0868 [Streptococcus pyogenes MGAS5005]; hypothetical protein 890996..891973 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112012 YP_002996619.1 CDS SDEG_0906 NC_012891.1 891974 892576 D similar to antigen [Streptococcus pyogenes MGAS5005]; hypothetical protein 891974..892576 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110433 YP_002996620.1 CDS SDEG_0907 NC_012891.1 892586 894310 D similar to multidrug resistance ABC transporter ATP-binding and permease protein [Streptococcus pyogenes MGAS10750]; multidrug resistance ABC transporter ATP-bindingprotein/permease 892586..894310 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110434 YP_002996621.1 CDS SDEG_0908 NC_012891.1 894307 896034 D similar to ABC transporter ATP-binding membrane protein [Streptococcus pyogenes str. Manfredo]; ABC transporter ATP-binding protein 894307..896034 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110435 YP_002996622.1 CDS nox NC_012891.1 896274 897641 D similar to NADH oxidase [Streptococcus pyogenes M1 GAS]; NADH oxidase 896274..897641 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110436 YP_002996623.1 CDS SDEG_0910 NC_012891.1 897710 898231 D similar to dihydrofolate reductase [Streptococcus suis 98HAH33]; dihydrofolate reductase 897710..898231 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111714 YP_002996624.1 CDS ldh NC_012891.1 898300 899283 R Converts (S)-lactate and NAD(+) to pyruvate and NADH; L-lactate dehydrogenase complement(898300..899283) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110437 YP_002996625.1 CDS gyrA NC_012891.1 899474 901978 D negatively supercoils closed circular double-stranded DNA; DNA gyrase subunit A 899474..901978 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110890 YP_002996626.1 CDS SDEG_0913 NC_012891.1 901987 902736 D similar to sortase [Streptococcus pyogenes NZ131]; sortase 901987..902736 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112025 YP_002996627.1 CDS SDEG_0914 NC_012891.1 902819 903232 D similar to lactoylglutathione lyase [Streptococcus pyogenes MGAS10394]; lactoylglutathione lyase 902819..903232 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110438 YP_002996628.1 CDS lmb NC_012891.1 903383 903559 D probable ORF of N-terminal portion of the Lmb protein [Streptococcus dysgalactiae subsp. equisimilis] resulted from mutation by unknown reason; laminin-binding surface protein 903383..903559 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110439 YP_002996629.1 CDS lmb NC_012891.1 903564 903932 D probable ORF of middlel portion of the Lmb protein [Streptococcus dysgalactiae subsp. equisimilis] resulted from mutation by unknown reason; laminin-binding surface protein 903564..903932 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110901 YP_002996630.1 CDS lmb NC_012891.1 903818 904318 D probable ORF of C-terminal portion of the Lmb protein [Streptococcus dysgalactiae subsp. equisimilis] resulted from mutation by unknown reason; laminin-binding surface protein 903818..904318 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110902 YP_002996631.1 CDS htpA NC_012891.1 904315 904773 D similar to histidine triad protein HtpA [Streptococcus equi subsp. zooepidemicus MGCS10565]; histidine triad protein 904315..904773 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110903 YP_002996632.1 CDS SDEG_0919 NC_012891.1 905046 906005 D similar to extracellular protein [Streptococcus equi subsp. zooepidemicus MGCS10565]; extracellular protein 905046..906005 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112039 YP_002996633.1 CDS SDEG_0920 NC_012891.1 906329 906478 R similar to transposase [Streptococcus pyogenes MGAS10750]; transposase complement(906329..906478) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110440 YP_002996634.1 CDS SDEG_0921 NC_012891.1 906471 907232 R similar to ISSdy1, transposase OrfB [Streptococcus agalactiae 2603V/R]; ISSdy1, transposase OrfB complement(906471..907232) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110441 YP_002996635.1 CDS SDEG_0922 NC_012891.1 907286 907576 R similar to ISSag4, transposase OrfA [Streptococcus agalactiae A909]; ISSag4, transposase orfA complement(907286..907576) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110442 YP_002996636.1 CDS SDEG_0923 NC_012891.1 907849 908133 D similar to hypothetical protein M6 Spy1729 [Streptococcus pyogenes MGAS10394]; hypothetical protein 907849..908133 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110443 YP_002996637.1 CDS SDEG_0924 NC_012891.1 908548 909810 D similar to periplasmic component of efflux system [Streptococcus pyogenes MGAS5005]; periplasmic protein of efflux system 908548..909810 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110444 YP_002996638.1 CDS SDEG_0925 NC_012891.1 909797 910471 D similar to ABC transporter ATP-binding protein [Streptococcus pyogenes MGAS5005]; ABC transporter ATP-binding protein 909797..910471 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110445 YP_002996639.1 CDS SDEG_0926 NC_012891.1 910484 911701 D similar to ABC transporter permease protein [Streptococcus pyogenes MGAS5005]; ABC transporter permease 910484..911701 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110446 YP_002996640.1 CDS irr NC_012891.1 911795 912448 D similar to two-component response regulator [Streptococcus pyogenes MGAS5005]; two-component response regulator 911795..912448 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110447 YP_002996641.1 CDS ihk NC_012891.1 912445 913833 D similar to two component system histidine kinase [Streptococcus pyogenes MGAS5005]; two component system histidine kinase 912445..913833 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110871 YP_002996642.1 CDS isp NC_012891.1 913935 915563 D similar to immunogenic secreted protein [Streptococcus pyogenes MGAS10270]; immunogenic secreted protein 913935..915563 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112049 YP_002996643.1 CDS SDEG_0930 NC_012891.1 915641 915892 D similar to hypothetical protein M28 Spy1706 [Streptococcus pyogenes MGAS6180]; hypothetical protein 915641..915892 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110873 YP_002996644.1 CDS SDEG_0931 NC_012891.1 916224 916913 D similar to hypothetical protein CdifQCD-6 20778 [Clostridium difficile QCD-63q42]; hypothetical protein 916224..916913 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110691 YP_002996645.1 CDS sic1-01 NC_012891.1 917183 917860 D similar to complement inhibitor protein [Streptococcus pyogenes MGAS2096]; complement inhibitor protein 917183..917860 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110692 YP_002996646.1 CDS scpB NC_012891.1 918282 921734 D similar to streptococcal C5a peptidase [Streptococcus agalactiae NEM316]; streptococcal C5a peptidase 918282..921734 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110485 YP_002996647.1 CDS SDEG_0934 NC_012891.1 921779 921895 D similar to hypothetical protein MGAS9429 Spy1719 [Streptococcus pyogenes MGAS9429]; hypothetical protein 921779..921895 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110468 YP_002996648.1 CDS lmb NC_012891.1 921986 922906 D similar to laminin binding protein [Streptococcus pyogenes MGAS5005]; laminin binding protein 921986..922906 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110693 YP_002996649.1 CDS SDEG_0936 NC_012891.1 922919 925387 D similar to streptococcal histidine triad protein [Streptococcus pyogenes MGAS10394]; histidine triad protein 922919..925387 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110904 YP_002996650.1 CDS SDEG_0937 NC_012891.1 925455 925685 R similar to hypothetical protein [Streptococcus suis]; hypothetical protein complement(925455..925685) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110694 YP_002996651.1 CDS SDEG_0938 NC_012891.1 925555 925755 D similar to CsbD-like protein [Streptococcus pyogenes str. Manfredo]; CsbD-like protein 925555..925755 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110695 YP_002996652.1 CDS dppE NC_012891.1 925836 926462 R similar to dipeptide transport ATP-binding protein [Streptococcus pyogenes MGAS5005]; dipeptide transport ATP-binding protein complement(925836..926462) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110696 YP_002996653.1 CDS dppD NC_012891.1 926446 927249 R similar to dipeptide transport ATP-binding protein [Streptococcus pyogenes MGAS5005]; dipeptide transport ATP-binding protein complement(926446..927249) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111860 YP_002996654.1 CDS dppC NC_012891.1 927261 928082 R similar to dipeptide transport system permease protein [Streptococcus pyogenes MGAS5005]; dipeptide transport system permease complement(927261..928082) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111859 YP_002996655.1 CDS dppB NC_012891.1 928079 929056 R similar to dipeptide transport system permease protein [Streptococcus pyogenes MGAS5005]; dipeptide transport system permease complement(928079..929056) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111858 YP_002996656.1 CDS dppA NC_012891.1 929169 930224 R similar to dipeptide-binding protein [Streptococcus pyogenes MGAS5005]; dipeptide-binding protein complement(929169..930224) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111857 YP_002996657.1 CDS dppA NC_012891.1 930218 930802 R similar to dipeptide-binding protein [Streptococcus pyogenes MGAS10394]; dipeptide-binding protein complement(930218..930802) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111855 YP_002996658.1 CDS SDEG_0945 NC_012891.1 931273 931398 D similar to transposase [Streptococcus pyogenes MGAS10394]; transposase 931273..931398 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111856 YP_002996659.1 CDS SDEG_0946 NC_012891.1 931426 932295 D similar to transposase [Streptococcus pyogenes MGAS10394]; transposase 931426..932295 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110697 YP_002996660.1 CDS SDEG_0947 NC_012891.1 932410 933633 D similar to UDP-N-acetylmuramoylpentapeptide-lysine N(6)-alanyltransferase / UDP-N-acetylmuramoylpentapeptide-lysine N(6)-seryltransferase [Streptococcus pyogenes MGAS10750]; UDP-N-acetylmuramoylpentapeptide-lysineN(6)- alanyltransferase/UDP-N-acetylmuramoylpentapeptide- lysineN(6)-seryltransferase 932410..933633 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110698 YP_002996661.1 CDS SDEG_0948 NC_012891.1 933734 934942 R similar to Na+/H+ antiporter [Streptococcus agalactiae A909]; Na+/H+ antiporter complement(933734..934942) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110699 YP_002996662.1 CDS tra NC_012891.1 935209 936186 D similar to IS1562 transposase [Streptococcus pyogenes MGAS8232]; IS1562 transposase 935209..936186 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110700 YP_002996663.1 CDS SDEG_0950 NC_012891.1 936190 936291 D similar to transposase [Streptococcus pyogenes MGAS10750]; transposase 936190..936291 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111922 YP_002996664.1 CDS SDEG_0951 NC_012891.1 936236 936652 D similar to transposase [Streptococcus pyogenes MGAS10750]; transposase 936236..936652 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110701 YP_002996665.1 CDS SDEG_0952 NC_012891.1 936951 937166 D similar to hypothetical protein CKL 3238 [Clostridium kluyveri DSM 555]; hypothetical protein 936951..937166 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110702 YP_002996666.1 CDS SDEG_0953 NC_012891.1 937163 938005 D similar to Type II restriction enzyme EcoRI [Parabacteroides distasonis ATCC 8503]; type II restriction enzyme EcoRI 937163..938005 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110703 YP_002996667.1 CDS SDEG_0954 NC_012891.1 938012 938995 D similar to type II restriction enzyme EcoRI-like protein [Microcystis aeruginosa NIES-843]; type II restriction enzyme EcoRI-like protein 938012..938995 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110704 YP_002996668.1 CDS SDEG_0955 NC_012891.1 939004 940458 R similar to transposase [Streptococcus pyogenes MGAS10394]; transposase complement(939004..940458) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110705 YP_002996669.1 CDS guaA NC_012891.1 940593 942155 R contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway; GMP synthase complement(940593..942155) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110706 YP_002996670.1 CDS SDEG_0957 NC_012891.1 942322 943764 D similar to hypothetical protein SpyM50880 [Streptococcus pyogenes str. Manfredo]; hypothetical protein 942322..943764 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112022 YP_002996671.1 CDS SDEG_0958 NC_012891.1 943844 944542 D similar to GntR family transcriptional regulator [Streptococcus pyogenes M1GAS]; GntR family transcriptional regulator 943844..944542 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110707 YP_002996672.1 CDS ylxM NC_012891.1 944643 944984 D similar to signal recognition particle associated protein [Streptococcus pyogenes MGAS10750]; DNA-binding protein 944643..944984 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110708 YP_002996673.1 CDS ffh NC_012891.1 944993 946561 D similar to signal recognition particle subunit FFH/SRP54 [Streptococcus pyogenes MGAS10270]; signal recognition particle subunit 944993..946561 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111967 YP_002996674.1 CDS SDEG_0961 NC_012891.1 946993 947574 D similar to ferric reductase [Oenococcus oeni PSU-1]; ferric reductase 946993..947574 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111889 YP_002996675.1 CDS SDEG_0962 NC_012891.1 947647 948048 D similar to predicted ferric reductase [Bifidobacterium animalis subsp. lactis HN019]; ferric reductase 947647..948048 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110709 YP_002996676.1 CDS SDEG_0963 NC_012891.1 948195 948887 R similar to phage transcriptional repressor [Streptococcus equi subsp.z ooepidemicus MGCS10565]; phage transcriptional repressor complement(948195..948887) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110710 YP_002996677.1 CDS SDEG_0964 NC_012891.1 949062 950087 D similar to oxidoreductase [Lactobacillus plantarum WCFS1]; oxidoreductase 949062..950087 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110711 YP_002996678.1 CDS SDEG_0965 NC_012891.1 950227 950775 D similar to DNA-binding response regulator [Streptococcus agalactiae 2603V/R]; DNA-binding response regulator 950227..950775 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110712 YP_002996679.1 CDS SDEG_0966 NC_012891.1 950759 951829 D similar to sensor histidine kinase [Streptococcus agalactiae 2603V/R]; sensor histidine kinase 950759..951829 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110713 YP_002996680.1 CDS SDEG_0967 NC_012891.1 951954 952376 D similar to hypothetical protein CAT7 10785 [Carnobacterium sp. AT7]; hypothetical protein 951954..952376 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110714 YP_002996681.1 CDS murO NC_012891.1 952407 952958 R similar to peptido glycan branched peptide synthesis protein, alanine adding enzyme [Streptococcust hermophilus CNRZ1066]; peptido glycan branched peptide synthesis protein, alanine adding enzyme complement(952407..952958) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110715 YP_002996682.1 CDS murO NC_012891.1 952967 953386 R similar to peptido glycan branched peptide synthesis protein, alanine adding enzyme [Streptococcus thermophilus CNRZ1066]; peptido glycan branched peptide synthesis protein, alanine adding enzyme complement(952967..953386) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111690 YP_002996683.1 CDS xerS NC_012891.1 954030 955100 D site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; cell division protein FtsK may regulate the XerS; site-specific tyrosine recombinase XerS 954030..955100 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111691 YP_002996684.1 CDS SDEG_0971 NC_012891.1 955177 955617 D similar to hypothetical protein SSU98 1762 [Streptococcus suis 98HAH33]; hypothetical protein 955177..955617 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111952 YP_002996685.1 CDS SDEG_0972 NC_012891.1 955688 956638 R similar to 14-dihydroxy-2-naphthoate octaprenyl transferase [Streptococcus suis 05ZYH33]; 1,4-dihydroxy-2-naphthoate octaprenyltransferase complement(955688..956638) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110716 YP_002996686.1 CDS SDEG_0973 NC_012891.1 956628 956957 R similar to membrane -associated lipoprotein involved in thiamine biosynthesis [Streptococcus suis 98HAH33]; thiamine biosynthesis lipoprotein complement(956628..956957) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110717 YP_002996687.1 CDS SDEG_0974 NC_012891.1 956950 957438 D similar to hypothetical protein SSU05 1758 [Streptococcus suis 05ZYH33]; hypothetical protein 956950..957438 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110718 YP_002996688.1 CDS bceS NC_012891.1 957497 958444 R similar to TCS senso kinase BceS [Streptococcus equi subsp. zooepidemicus MGCS10565]; two component system histidine kinase complement(957497..958444) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110719 YP_002996689.1 CDS bceR NC_012891.1 958441 959106 R similar to TCS response regulator BceR [Streptococcus equi subsp. zooepidemicus MGCS10565]; two-component response regulator complement(958441..959106) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112369 YP_002996690.1 CDS bceB NC_012891.1 959150 961105 R similar to bacitracin export permease protein BceB [Streptococcus equi subsp. zooepidemicus MGCS10565]; bacitracin export permease complement(959150..961105) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112368 YP_002996691.1 CDS SDEG_0978 NC_012891.1 961107 961859 R similar to ABC transporter ATP-binding protein [Streptococcus equi subsp. zooepidemicus MGCS10565]; ABC transporter ATP-binding protein complement(961107..961859) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112367 YP_002996692.1 CDS SDEG_0979 NC_012891.1 961896 962861 R similar to nisin-resistanceprotein, [Streptococcus agalactiae 2603V/R]; nisin-resistanceprotein complement(961896..962861) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110720 YP_002996693.1 CDS SDEG_0980 NC_012891.1 963027 963509 D similar to hypothetical protein MGAS10750 Spy1061 [Streptococcus pyogenes MGAS10750]; hypothetical protein 963027..963509 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110721 YP_002996694.1 CDS citC NC_012891.1 963776 964828 D similar to (citrate [pro-3S]-lyase)-ligase [Streptococcus pyogenes MGAS5005]; (citrate [pro-3S]-lyase)-ligase 963776..964828 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110722 YP_002996695.1 CDS oadA1 NC_012891.1 964964 966358 R Converts oxaloacetate to phosphoenolpyruvate using ATP as an energy source; oxaloacetate decarboxylase complement(964964..966358) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111615 YP_002996696.1 CDS SDEG_0983 NC_012891.1 966662 967891 D similar to transposase [Streptococcus pneumoniae SP9-BS68]; transposase 966662..967891 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111728 YP_002996697.1 CDS citX NC_012891.1 967991 968665 R 2'-(5''-phosphoribosyl)-3'-dephospho-CoA transferase; holo-citrate lyase synthase; CitG forms the prosthetic group precursor 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA which is then transferred to apo-ACP by CitX to produce holo-ACP and pyrophosphate; 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase complement(967991..968665) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110723 YP_002996698.1 CDS citF NC_012891.1 968562 970094 R similar to citrate CoA-transferase [Streptococcus pyogenes MGAS10394]; citrate CoA-transferase complement(968562..970094) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111620 YP_002996699.1 CDS citE NC_012891.1 970097 970984 R similar to citrate lyase beta chain [Streptococcus pyogenes MGAS10394]; citrate lyase subunit beta complement(970097..970984) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111618 YP_002996700.1 CDS citD NC_012891.1 970972 971280 R acyl carrier protein; with CitE and CitF catalyzes the formation of oxaloacetate from citrate; citrate lyase subunit gamma complement(970972..971280) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111617 YP_002996701.1 CDS SDEG_0988 NC_012891.1 971316 971450 R similar to hypothetical protein M5005 Spy 0904 [Streptococcus pyogenes MGAS5005]; hypothetical protein complement(971316..971450) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111616 YP_002996702.1 CDS oadB NC_012891.1 971468 972589 R similar to oxaloacetate decarboxylase beta chain [Streptococcus pyogenes MGAS5005]; oxaloacetate decarboxylase subunit beta complement(971468..972589) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110724 YP_002996703.1 CDS SDEG_0990 NC_012891.1 972634 973029 R composes the biotin carboxyl carrier protein subunit of the acetyl-CoA carboxylase complex, the enzyme that catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, which in turn controls the rate of fatty acid metabolism; acetyl-CoA carboxylase biotin carboxyl carrier protein subunit complement(972634..973029) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111730 YP_002996704.1 CDS SDEG_0991 NC_012891.1 973091 973414 R similar to hypothetical protein MGAS10750 Spy1050 [Streptococcus pyogenes MGAS10750]; hypothetical protein complement(973091..973414) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110725 YP_002996705.1 CDS SDEG_0992 NC_012891.1 973795 975198 D similar to Mg2+/citrate complex secondary transporter [Streptococcus pyogenes MGAS5005]; Mg2+/citrate complex secondary transporter 973795..975198 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110726 YP_002996706.1 CDS citG NC_012891.1 975356 976051 D similar to GntR family transcriptional regulator [Streptococcus pyogenes MGAS5005]; GntR family transcriptional regulator 975356..976051 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110727 YP_002996707.1 CDS SDEG_0994 NC_012891.1 976044 976928 D similar to 2-(5''-triphosphoribosyl)-3'- dephosphocoenzyme-A synthase [Streptococcus pyogenes MGAS5005]; 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase 976044..976928 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111619 YP_002996708.1 CDS SDEG_0995 NC_012891.1 977049 978113 R similar to ammonia monooxygenase [Streptococcus equi subsp. zooepidemicus MGCS10565]; ammonia monooxygenase complement(977049..978113) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110728 YP_002996709.1 CDS SDEG_0996 NC_012891.1 978295 979425 R similar to oxaloacetate decarboxylase beta chain [Streptococcus pyogenes MGAS10394]; oxaloacetate decarboxylase subunit beta complement(978295..979425) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110729 YP_002996710.1 CDS SDEG_0997 NC_012891.1 979435 979785 R similar to methylmalonyl-CoA decarboxylase gamma-subunit [Streptococcus pyogenes MGAS315]; methylmalonyl-CoA decarboxylase gamma-subunit complement(979435..979785) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110730 YP_002996711.1 CDS SDEG_0998 NC_012891.1 979785 980099 R similar to hypothetical membrane associated protein [Streptococcus pyogenes MGAS10394]; hypothetical protein complement(979785..980099) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110731 YP_002996712.1 CDS oadA2 NC_012891.1 980142 981524 R Converts oxaloacetate to phosphoenolpyruvate using ATP as an energy source; oxaloacetate decarboxylase complement(980142..981524) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110732 YP_002996713.1 CDS gid NC_012891.1 981701 983095 R TrmFO; Gid; glucose-inhibited division protein; similar to GidA; the gene from Bacillus subtilis encodes a tRNA-methyltransferase that utilizes folate as the carbon donor and bound flavin as reductant; modifies tRNA at position 54 (uridine) of the T-psi loop to form a C5-methyluridine; tRNA (uracil-5-)-methyltransferase Gid complement(981701..983095) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111729 YP_002996714.1 CDS satE NC_012891.1 983198 983914 R similar to hypothetical protein MGAS10270 Spy1006 [Streptococcus pyogenes MGAS10270]; hypothetical protein complement(983198..983914) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111991 YP_002996715.1 CDS satD NC_012891.1 983907 984572 R similar to hypothetical protein MGAS10270 Spy1005 [Streptococcus pyogenes MGAS10270]; hypothetical protein complement(983907..984572) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110463 YP_002996716.1 CDS ddh NC_012891.1 984679 985665 R catalyzes the formation of pyruvate from lactate; D-lactate dehydrogenase complement(984679..985665) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110462 YP_002996717.1 CDS SDEG_1004 NC_012891.1 985809 986705 R similar to hypothetical protein SAK 0820 [Streptococcus agalactiae A909]; hypothetical protein complement(985809..986705) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111662 YP_002996718.1 CDS SDEG_1005 NC_012891.1 986893 987837 D similar to transposase [Streptococcus pyogenes MGAS2096]; transposase 986893..987837 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110733 YP_002996719.1 CDS SDEG_1006 NC_012891.1 987860 988021 D similar to transcriptional regulator, LysR family [Streptococcus agalactiae H36B]; LysR family transcriptional regulator 987860..988021 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110734 YP_002996720.1 CDS SDEG_1007 NC_012891.1 988132 988743 D similar to hypothetical protein gbs0666 [Streptococcus agalactiae NEM316]; hypothetical protein 988132..988743 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110735 YP_002996721.1 CDS SDEG_1008 NC_012891.1 988819 990951 R catalyzes the ATP-dependent breakage of single-stranded DNA followed by passage and rejoining, maintains net negative superhelicity; DNA topoisomerase I complement(988819..990951) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110736 YP_002996722.1 CDS smf NC_012891.1 991052 991894 R similar to DNA processing protein [Streptococcus pyogenes MGAS10750]; DNA processing protein complement(991052..991894) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110737 YP_002996723.1 CDS rnhB NC_012891.1 992001 992771 R RNH2; RNase HII; binds manganese; endonuclease which specifically degrades the RNA of RNA-DNA hybrids; ribonuclease HII complement(992001..992771) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110491 YP_002996724.1 CDS rbgA NC_012891.1 992761 993609 R essential GTPase; functions in ribosome assembly; binds a unique part of the 23S rRNA; interacts with ribosomal protein L25(Ctc); ribosomal biogenesis GTPase complement(992761..993609) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111051 YP_002996725.1 CDS SDEG_1012 NC_012891.1 994332 994562 R similar to hypothetical protein SPCG 0150 [Streptococcus pneumoniae CGSP14]; hypothetical protein complement(994332..994562) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110738 YP_002996726.1 CDS SDEG_1013 NC_012891.1 994781 995668 R similar to XRE family transcriptional regulator [Streptococcus thermophilus LMD-9]; XRE family transcriptional regulator complement(994781..995668) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110739 YP_002996727.1 CDS SDEG_1014 NC_012891.1 996008 996448 D similar to hypothetical cytosolic protein [Streptococcus pyogenes MGAS10750]; hypothetical protein 996008..996448 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110740 YP_002996728.1 CDS SDEG_1015 NC_012891.1 996445 997095 D similar to hypothetical protein M5005 Spy 0880 [Streptococcus pyogenes MGAS5005]; hypothetical protein 996445..997095 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110741 YP_002996729.1 CDS SDEG_1016 NC_012891.1 997213 998124 D similar to diacylglycerol kinase family protein [Streptococcus pyogenes MGAS2096]; diacylglycerol kinase 997213..998124 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110742 YP_002996730.1 CDS SDEG_1017 NC_012891.1 998164 998613 R similar to hypothetical protein M28 Spy0852 [Streptococcus pyogenes MGAS6180]; hypothetical protein complement(998164..998613) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110743 YP_002996731.1 CDS SDEG_1018 NC_012891.1 998750 998956 R similar to hypothetical protein MGAS2096 Spy1031 [Streptococcus pyogenes MGAS2096]; hypothetical protein complement(998750..998956) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110744 YP_002996732.1 CDS SDEG_1019 NC_012891.1 999285 1000880 R similar to ABC transporter ATP-binding protein [Streptococcus pyogenes MGAS6180]; ABC transporter ATP-binding protein complement(999285..1000880) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110745 YP_002996733.1 CDS skc NC_012891.1 1000932 1002050 R plasminogen activator; similar to streptokinase precursor [Streptococcus dysgalactiae subsp. equisimilis]; streptokinase complement(1000932..1002050) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110746 YP_002996734.1 CDS SDEG_1021 NC_012891.1 1002400 1002960 R similar to hypothetical protein spyM18 1159 [Streptococcus pyogenes MGAS8232]; hypothetical protein complement(1002400..1002960) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110488 YP_002996735.1 CDS pdxK NC_012891.1 1002957 1003793 R catalyzes the formation of pyridoxal 5'-phosphate from pyridoxal; pyridoxamine kinase complement(1002957..1003793) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110747 YP_002996736.1 CDS SDEG_1023 NC_012891.1 1003895 1005160 D similar to transcriptional regulator; transcriptional regulator 1003895..1005160 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111757 YP_002996737.1 CDS SDEG_1024 NC_012891.1 1005221 1005577 R similar to hypothetical protein SPs1051 [Streptococcus pyogenes SSI-1]; hypothetical protein complement(1005221..1005577) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110748 YP_002996738.1 CDS asd NC_012891.1 1005700 1006776 R catalyzes the formation of 4-aspartyl phosphate from aspartate 4-semialdehyde; aspartate-semialdehyde dehydrogenase complement(1005700..1006776) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110749 YP_002996739.1 CDS SDEG_1026 NC_012891.1 1007064 1008641 R similar to cardiolipin synthetase [Streptococcus pyogenes MGAS10394]; cardiolipin synthetase complement(1007064..1008641) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112347 YP_002996740.1 CDS scp NC_012891.1 1009011 1009970 R similar to C5a peptidase precursor ScpZ [Streptococcus equi subsp. zooepidemicusMGCS10565]; C5a peptidase complement(1009011..1009970) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110750 YP_002996741.1 CDS SDEG_1028 NC_012891.1 1010049 1010336 R similar to ISSdy1, transposase OrfB [Streptococcus agalactiae 2603V/R]; ISSdy1, transposase OrfB complement(1010049..1010336) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110465 YP_002996742.1 CDS SDEG_1029 NC_012891.1 1010454 1010567 R similar to ISSdy1, transposase OrfA [Streptococcus agalactiae 2603V/R]; ISSdy1, transposase OrfA complement(1010454..1010567) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110751 YP_002996743.1 CDS SDEG_1030 NC_012891.1 1010636 1010743 R similar to transposase [Streptococcus agalactiae]; transposase complement(1010636..1010743) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110752 YP_002996744.1 CDS SDEG_1031 NC_012891.1 1010869 1011672 R similar to transposase [Streptococcus pyogenes str. Manfredo]; transposase complement(1010869..1011672) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110753 YP_002996745.1 CDS tnpA NC_012891.1 1011725 1011994 R similar to probable transposase TnpA (fragment) [Streptococcus pyogenes MGAS315]; transposase complement(1011725..1011994) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110754 YP_002996746.1 CDS fhs1 NC_012891.1 1012631 1014301 R catalyzes the formation of 10-formyltetrahydrofolate from formate and tetrahydrofolate; formate--tetrahydrofolate ligase complement(1012631..1014301) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110528 YP_002996747.1 CDS lplA NC_012891.1 1014428 1015447 R similar to lipoate-protein ligase A [Streptococcus pyogenes MGAS10394]; lipoate-protein ligase A complement(1014428..1015447) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111890 YP_002996748.1 CDS SDEG_1035 NC_012891.1 1015462 1016373 R similar to SIR2 family protein [Streptococcus pyogenes MGAS10394]; SIR2 family protein complement(1015462..1016373) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110906 YP_002996749.1 CDS SDEG_1036 NC_012891.1 1016360 1017172 R similar to hypothetical protein M5005 Spy 0930 [Streptococcus pyogenes MGAS5005]; hypothetical protein complement(1016360..1017172) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110755 YP_002996750.1 CDS SDEG_1037 NC_012891.1 1017165 1017497 R similar to glycine cleavage system H protein [Streptococcus pyogenes MGAS5005]; glycine cleavage system H protein complement(1017165..1017497) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110756 YP_002996751.1 CDS yqiG NC_012891.1 1017729 1018928 R similar to probable NADH-dependent flavin oxidoreductase [Streptococcus pyogenes MGAS10394]; NADH-dependent flavin oxidoreductase complement(1017729..1018928) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110757 YP_002996752.1 CDS SDEG_1039 NC_012891.1 1018928 1019761 R similar to lipoate-protein ligase A [Streptococcus pyogenes MGAS5005]; lipoate-protein ligase A complement(1018928..1019761) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111968 YP_002996753.1 CDS dpfB NC_012891.1 1019978 1020670 D similar to phosphopantothenate-cysteine ligase [Streptococcus pyogenes MGAS10270]; phosphopantothenate--cysteine ligase 1019978..1020670 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110758 YP_002996754.1 CDS coaC NC_012891.1 1020663 1021208 D decarboxylates 4-phosphopantothenoylcysteine to form 4'-phosphopantotheine.; phosphopantothenoylcysteine decarboxylase 1020663..1021208 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111852 YP_002996755.1 CDS SDEG_1042 NC_012891.1 1021263 1021853 D similar to integral membrane protein [Streptococcus pyogenes MGAS10750]; integral membrane protein 1021263..1021853 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111629 YP_002996756.1 CDS pgmA NC_012891.1 1022016 1023734 D similar to phosphomannomutase PgmA [Streptococcusequi subsp. zooepidemicus MGCS10565]; phosphomannomutase 1022016..1023734 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110759 YP_002996757.1 CDS SDEG_1044 NC_012891.1 1023902 1024870 R similar to nucleoside transport system permease protein [Streptococcus pyogenes MGAS10394]; nucleoside transport system permease complement(1023902..1024870) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111287 YP_002996758.1 CDS SDEG_1045 NC_012891.1 1024860 1025924 R similar to nucleoside transportsystem permease protein [Streptococcus pyogenes MGAS6180]; nucleoside transport ATP-binding protein complement(1024860..1025924) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110760 YP_002996759.1 CDS SDEG_1046 NC_012891.1 1025917 1027467 R similar to nucleoside transport ATP-binding protein [Streptococcus pyogenes MGAS10270]; nucleoside transport ATP-binding protein complement(1025917..1027467) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110761 YP_002996760.1 CDS SDEG_1047 NC_012891.1 1027581 1028633 R similar to nucleoside-binding protein [Streptococcus pyogenes MGAS10394]; nucleoside-binding protein complement(1027581..1028633) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110762 YP_002996761.1 CDS cdd NC_012891.1 1028727 1029116 R Reclaims exogenous and endogenous cytidine and 2'-deoxycytidine molecules for UMP synthesis; cytidine deaminase complement(1028727..1029116) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110763 YP_002996762.1 CDS deoC NC_012891.1 1029103 1029765 R catalyzes the formation of D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-D-ribose-5-phosphate; deoxyribose-phosphate aldolase complement(1029103..1029765) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111610 YP_002996763.1 CDS pdp NC_012891.1 1029781 1031058 R Catalyzes the reversible phosphorolysis of pyrimidines in the nucleotide synthesis salvage pathway; pyrimidine-nucleoside phosphorylase complement(1029781..1031058) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111668 YP_002996764.1 CDS SDEG_1051 NC_012891.1 1031045 1031677 R similar to 16S rRNA m(2)G 1207 methyltransferase [Streptococcus pyogenes MGAS10750]; 16S rRNA m(2)G 1207 methyltransferase complement(1031045..1031677) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111756 YP_002996765.1 CDS coaA NC_012891.1 1031913 1032833 D catalyzes the formation of (R)-4'-phosphopantothenate in coenzyme A biosynthesis; pantothenate kinase 1031913..1032833 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110764 YP_002996766.1 CDS rpsT NC_012891.1 1032887 1033135 D binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase; 30S ribosomal protein S20 1032887..1033135 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111628 YP_002996767.1 CDS SDEG_1054 NC_012891.1 1033293 1034603 R similar to histidine kinase protein [Streptococcus pyogenes MGAS8232]; histidine kinase protein complement(1033293..1034603) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110448 YP_002996768.1 CDS SDEG_1055 NC_012891.1 1034596 1035270 R similar to response regulator [Streptococcus pyogenes MGAS8232]; response regulator complement(1034596..1035270) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110765 YP_002996769.1 CDS pepN NC_012891.1 1035474 1038035 R similar to lysyl aminopeptidase / alanine aminopeptidase [Streptococcus pyogenes MGAS10750]; lysyl aminopeptidase/alanine aminopeptidase complement(1035474..1038035) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110766 YP_002996770.1 CDS phoU NC_012891.1 1038212 1038865 R similar to phosphate transport system protein [Streptococcus pyogenes MGAS5005]; phosphate transport system protein complement(1038212..1038865) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111277 YP_002996771.1 CDS pstB NC_012891.1 1038943 1039704 R ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation; phosphate transporter ATP-binding protein complement(1038943..1039704) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111294 YP_002996772.1 CDS pstB2 NC_012891.1 1039714 1040517 R ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation; phosphate transporter ATP-binding protein complement(1039714..1040517) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111316 YP_002996773.1 CDS pstA NC_012891.1 1040533 1041420 R similar to phosphate transport system permease protein [Streptococcus pyogenes MGAS5005]; phosphate ABC transporter permease complement(1040533..1041420) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111317 YP_002996774.1 CDS pstC NC_012891.1 1041410 1042345 R similar to phosphate transport system permease protein pstC [Streptococcus pyogenes MGAS10750]; phosphate ABC transporter permease complement(1041410..1042345) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111315 YP_002996775.1 CDS pstS NC_012891.1 1042356 1043222 R similar to phosphate-binding protein [Streptococcus pyogenes MGAS5005]; phosphate-binding protein complement(1042356..1043222) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111318 YP_002996776.1 CDS SDEG_1063 NC_012891.1 1043362 1044672 R similar to 23S rRNA m(5)C methyltransferase [Streptococcus pyogenes MGAS10750]; 23S rRNA m(5)C methyltransferase complement(1043362..1044672) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111320 YP_002996777.1 CDS SDEG_1064 NC_012891.1 1044688 1045467 R similar to myo-inositol-1(or 4)-monophosphatase [Streptococcus pyogenes MGAS8232]; myo-inositol-1(or 4)-monophosphatase complement(1044688..1045467) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110767 YP_002996778.1 CDS SDEG_1065 NC_012891.1 1045457 1045735 R similar to hypothetical protein M6 Spy0948 [Streptococcus pyogenes MGAS10394]; hypothetical protein complement(1045457..1045735) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110768 YP_002996779.1 CDS spxA NC_012891.1 1045737 1046141 R the anti-alpha factor Spx interacts with RNA polymerase alpha subunit C-terminal domain in a region that interacts with the sigma 70 subunit and may interfere with activation of promoters; in Bacillus subtilis this protein is a substrate for ClpXP protease; blocks transcription of the competence regulatory gene encoded by the srf operon; regulates a number of genes involved in thiol homeostasis including trxA and trxB; monomeric member of ArsC family of proteins; does not bind DNA; contains a disulfide bond between C10 and C13 which may sense disulfide stress; transcriptional regulator Spx complement(1045737..1046141) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110769 YP_002996780.1 CDS ribC NC_012891.1 1046184 1047116 R catalyzes the formation of FMN from riboflavin and the formation of FAD from FMN; in Bacillus the ribC gene has both flavokinase and FAD synthetase activities; bifunctional riboflavin kinase/FMN adenylyltransferase complement(1046184..1047116) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110501 YP_002996781.1 CDS paaB NC_012891.1 1047154 1047540 R similar to transposase [Streptococcus criceti]; transposase complement(1047154..1047540) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111049 YP_002996782.1 CDS SDEG_1069 NC_012891.1 1047597 1048016 R similar to transposase [Streptococcus pyogenes MGAS2096]; transposase complement(1047597..1048016) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111746 YP_002996783.1 CDS truB NC_012891.1 1048111 1048995 R catalyzes isomerization of specific uridines in RNA to pseudouridine; responsible for residues in T loops of many tRNAs; tRNA pseudouridine synthase B complement(1048111..1048995) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110770 YP_002996784.1 CDS SDEG_1071 NC_012891.1 1049111 1050451 R similar to COG4487, uncharacterized protein conserved in bacteria [Streptococcus pyogenes M49 591]; hypothetical protein complement(1049111..1050451) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111931 YP_002996785.1 CDS SDEG_1072 NC_012891.1 1050557 1051513 R similar to integral membrane protein [Streptococcus pyogenes MGAS10750]; integral membrane protein complement(1050557..1051513) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110771 YP_002996786.1 CDS SDEG_1073 NC_012891.1 1051524 1052120 R similar to hypothetical protein SpyM3 0890 [Streptococcus pyogenes MGAS315]; hypothetical protein complement(1051524..1052120) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110949 YP_002996787.1 CDS SDEG_1074 NC_012891.1 1052202 1054847 R similar to ABC transporter permease protein [Streptococcus pyogenes MGAS2096]; ABC transporter permease complement(1052202..1054847) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110950 YP_002996788.1 CDS SDEG_1075 NC_012891.1 1054857 1055558 R similar to ABC transporter (ATP-binding protein) [Streptococcus pyogenes MGAS8232]; ABC transporter ATP-binding protein complement(1054857..1055558) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110951 YP_002996789.1 CDS tetR NC_012891.1 1055678 1056229 D similar to TetR family transcriptional regulator [Streptococcus pyogenes MGAS10270]; TetR family transcriptional regulator 1055678..1056229 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110952 YP_002996790.1 CDS SDEG_1077 NC_012891.1 1056346 1056987 R similar to transcriptional regulator [Streptococcus pyogenes M1 GAS]; transcriptional regulator complement(1056346..1056987) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110515 YP_002996791.1 CDS SDEG_1078 NC_012891.1 1057147 1057635 R similar to Gls24 family general stress protein [Streptococcus pyogenes MGAS10394]; Gls24 family general stress protein complement(1057147..1057635) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110953 YP_002996792.1 CDS SDEG_1079 NC_012891.1 1057901 1058440 R similar to hypothetical protein SpyM50827 [Streptococcus pyogenes str. Manfredo]; hypothetical protein complement(1057901..1058440) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110954 YP_002996793.1 CDS SDEG_1080 NC_012891.1 1058464 1058652 R similar to hypothetical protein SPy 1263 [Streptococcus pyogenes M1 GAS]; hypothetical protein complement(1058464..1058652) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110955 YP_002996794.1 CDS SDEG_1081 NC_012891.1 1058663 1059244 R similar to hypothetical protein spyM18 1215 [Streptococcus pyogenes MGAS8232]; hypothetical protein complement(1058663..1059244) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110956 YP_002996795.1 CDS SDEG_1082 NC_012891.1 1059305 1059553 R similar to hypothetical protein SpyM50824 [Streptococcus pyogenes str. Manfredo]; hypothetical protein complement(1059305..1059553) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110957 YP_002996796.1 CDS SDEG_1083 NC_012891.1 1059923 1062241 R similar to DNA helicase II [Streptococcus pyogenes MGAS10394]; DNA helicase II complement(1059923..1062241) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110958 YP_002996797.1 CDS SDEG_1084 NC_012891.1 1062762 1064099 D similar to amino acid symporter [Streptococcus pyogenes MGAS315]; amino acid symporter 1062762..1064099 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110959 YP_002996798.1 CDS czcD NC_012891.1 1064205 1065440 D similar to cobalt-zinc-cadmium resistance protein czcD [Streptococcus pyogenes MGAS10270]; cobalt-zinc-cadmium resistance protein 1064205..1065440 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110960 YP_002996799.1 CDS SDEG_1086 NC_012891.1 1065476 1065877 R similar to transposase [Streptococcus pyogenes MGAS10394]; transposase complement(1065476..1065877) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111659 YP_002996800.1 CDS SDEG_1087 NC_012891.1 1065720 1066919 R similar to transposase [Streptococcus pyogenes MGAS10394]; transposase complement(1065720..1066919) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110961 YP_002996801.1 CDS SDEG_1088 NC_012891.1 1067151 1067993 R similar to amino acid ABC transporter extracellular-binding protein precursor [Streptococcus equi subsp. zooepidemicus MGCS10565]; amino acid ABC transporter substrate-binding protein complement(1067151..1067993) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110962 YP_002996802.1 CDS SDEG_1089 NC_012891.1 1068006 1068635 R similar to histidine transport ATP-binding protein hisP [Streptococcus pyogenes MGAS10750]; histidine ABC transporter ATP-binding protein complement(1068006..1068635) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110963 YP_002996803.1 CDS hisM NC_012891.1 1068645 1069286 R similar to histidine transport system permease protein hisM [Streptococcus pyogenes MGAS10270]; histidine transport system permease complement(1068645..1069286) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110964 YP_002996804.1 CDS SDEG_1091 NC_012891.1 1069393 1069728 R similar to hypothetical protein spyM18 1226 [Streptococcus pyogenes MGAS8232]; hypothetical protein complement(1069393..1069728) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112031 YP_002996805.1 CDS glmS NC_012891.1 1069926 1071740 R Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source; glucosamine--fructose-6-phosphate aminotransferase complement(1069926..1071740) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110965 YP_002996806.1 CDS sipC NC_012891.1 1071924 1072481 R similar to signal peptidase I [Streptococcus pyogenes MGAS2096]; signal peptidase I complement(1071924..1072481) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112001 YP_002996807.1 CDS pyk NC_012891.1 1072647 1074149 R catalyzes the formation of phosphoenolpyruvate from pyruvate; pyruvate kinase complement(1072647..1074149) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110487 YP_002996808.1 CDS pfkA NC_012891.1 1074212 1075225 R catalyzes the formation of D-fructose 1,6-bisphosphate from D-fructose 6-phosphate in glycolysis; 6-phosphofructokinase complement(1074212..1075225) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111337 YP_002996809.1 CDS dnaE NC_012891.1 1075305 1078415 R Catalyzes DNA-template-directed extension of the 3'-end of a DNA strand by one nucleotide at a time. Proposed to be responsible for the synthesis of the lagging strand. In the low GC gram positive bacteria this enzyme is less processive and more error prone than its counterpart in other bacteria.; DNA polymerase III DnaE complement(1075305..1078415) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111283 YP_002996810.1 CDS SDEG_1097 NC_012891.1 1078602 1078973 D similar to transcriptional regulator GntR family [Streptococcus pyogenes MGAS10750]; GntR family transcriptional regulator 1078602..1078973 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111845 YP_002996811.1 CDS SDEG_1098 NC_012891.1 1078973 1079671 D similar to ABC transporter ATP-binding protein [Streptococcus pyogenes str. Manfredo]; ABC transporter ATP-binding protein 1078973..1079671 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110966 YP_002996812.1 CDS SDEG_1099 NC_012891.1 1079681 1080469 D similar to hypothetical protein SpyM3 0917 [Streptococcus pyogenes MGAS315]; hypothetical protein 1079681..1080469 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110967 YP_002996813.1 CDS SDEG_1100 NC_012891.1 1080605 1081219 R similar to hypothetical protein spyM18 1236 [Streptococcus pyogenes MGAS8232]; hypothetical protein complement(1080605..1081219) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110968 YP_002996815.1 CDS SDEG_1102 NC_012891.1 1081810 1081998 R similar to unknown phage protein [Streptococcus pyogenes MGAS10394]; phage protein complement(1081810..1081998) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110970 YP_002996816.1 CDS sdc NC_012891.1 1082237 1083220 D similar to deoxyribonuclease [Streptococcus dysgalactiae subsp. equisimilis]; deoxyribonuclease 1082237..1083220 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110971 YP_002996817.1 CDS SDEG_1104 NC_012891.1 1083282 1083482 R similar to CsbD-like phage protein [Streptococcus pyogenes str. Manfredo]; CsbD-like phage protein complement(1083282..1083482) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110473 YP_002996818.1 CDS SDEG_1105 NC_012891.1 1083671 1084183 R similar to hypothetical protein CGSSp14BS69 08645 [Streptococcus pneumoniae SP14-BS69]; hypothetical protein complement(1083671..1084183) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110972 YP_002996819.1 CDS SDEG_1106 NC_012891.1 1084580 1085782 R similar to lysin [Streptococcus phage P9]; lysin complement(1084580..1085782) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110973 YP_002996820.1 CDS SDEG_1107 NC_012891.1 1085770 1085892 R similar to hypothetical protein P9 gp49 [Streptococcus phage P9]; hypothetical protein complement(1085770..1085892) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110974 YP_002996821.1 CDS SDEG_1108 NC_012891.1 1085894 1086349 R similar to Holin [Streptococcus pyogenes MGAS10394]; holin complement(1085894..1086349) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110975 YP_002996822.1 CDS SDEG_1109 NC_012891.1 1086352 1087008 R similar to phage protein [Streptococcus pyogenes MGAS10750]; phage protein complement(1086352..1087008) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110976 YP_002996823.1 CDS SDEG_1110 NC_012891.1 1087011 1087439 R similar to hypothetical protein spyM18 1755 [Streptococcus pyogenes MGAS8232]; hypothetical protein complement(1087011..1087439) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110977 YP_002996824.1 CDS SDEG_1111 NC_012891.1 1087449 1089158 R similar to hypothetical protein SpyM50681 [Streptococcus pyogenes str. Manfredo]; hypothetical protein complement(1087449..1089158) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110978 YP_002996825.1 CDS SDEG_1112 NC_012891.1 1089167 1089820 R similar to phage protein [Streptococcus phage 10270.2]; phage protein complement(1089167..1089820) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110979 YP_002996826.1 CDS SDEG_1113 NC_012891.1 1089820 1090605 R similar to hyaluronoglucosaminidase [Streptococcus pyogenes MGAS10394]; hyaluronoglucosaminidase complement(1089820..1090605) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110980 YP_002996827.1 CDS SDEG_1114 NC_012891.1 1090602 1091813 R probable C-terminal portion of phage endopeptidase [Streptococcus pyogenes MGAS10394]; phage endopeptidase complement(1090602..1091813) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110981 YP_002996828.1 CDS SDEG_1115 NC_012891.1 1091870 1092544 R probable N-terminal portion of phage endopeptidase [Streptococcus pyogenes MGAS10394]; phage endopeptidase complement(1091870..1092544) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110982 YP_002996829.1 CDS SDEG_1116 NC_012891.1 1092541 1093236 R similar to hypothetical protein spyM18 1457 [Streptococcus pyogenes MGAS8232]; hypothetical protein complement(1092541..1093236) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110983 YP_002996830.1 CDS SDEG_1117 NC_012891.1 1093233 1095083 R similar to phage protein [Streptococcus pyogenes MGAS5005]; phage protein complement(1093233..1095083) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110984 YP_002996831.1 CDS SDEG_1118 NC_012891.1 1095252 1095812 R similar to endodeoxyribonuclease [Lactococcus phage r1t]; endodeoxyribonuclease complement(1095252..1095812) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110985 YP_002996832.1 CDS SDEG_1119 NC_012891.1 1095899 1096489 R similar to N-terminal of phage protein [Streptococcus pyogenes MGAS5005]; phage protein complement(1095899..1096489) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110986 YP_002996833.1 CDS SDEG_1120 NC_012891.1 1096489 1096860 R similar to phage protein [Streptococcus pyogenes MGAS5005]; phage protein complement(1096489..1096860) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110987 YP_002996834.1 CDS SDEG_1121 NC_012891.1 1097149 1097745 R similar to major tail protein [Streptococcus pyogenes MGAS5005]; major tail protein complement(1097149..1097745) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110988 YP_002996835.1 CDS SDEG_1122 NC_012891.1 1097754 1098089 R similar to unknown phage protein [Streptococcus pyogenes MGAS10394]; phage protein complement(1097754..1098089) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110989 YP_002996836.1 CDS SDEG_1123 NC_012891.1 1098090 1098335 R similar to unknown phage protein [Streptococcus pyogenes MGAS10394]; phage protein complement(1098090..1098335) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110990 YP_002996837.1 CDS SDEG_1124 NC_012891.1 1098319 1098657 R similar to phage protein [Streptococcus pyogenes MGAS5005]; phage protein complement(1098319..1098657) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110991 YP_002996838.1 CDS SDEG_1125 NC_012891.1 1098620 1099039 R similar to phage protein [Streptococcus pyogenes MGAS5005]; phage protein complement(1098620..1099039) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110992 YP_002996839.1 CDS SDEG_1126 NC_012891.1 1099060 1099293 R similar to conserved hypothetical protein (phage associated) [Streptococcus suis 89/1591]; hypothetical protein complement(1099060..1099293) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110993 YP_002996840.1 CDS SDEG_1127 NC_012891.1 1099295 1100188 R similar to structural protein - phage associated [Streptococcus suis 89 /1591]; phage associated structural protein complement(1099295..1100188) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110994 YP_002996841.1 CDS SDEG_1128 NC_012891.1 1100206 1100793 R similar to phage protein [Streptococcus pyogenes MGAS10750]; phage protein complement(1100206..1100793) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110995 YP_002996842.1 CDS SDEG_1129 NC_012891.1 1100726 1102156 R similar to phage terminase [Streptococcus pyogenes MGAS10750]; phage terminase complement(1100726..1102156) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110996 YP_002996843.1 CDS SDEG_1130 NC_012891.1 1102205 1102474 R similar to hypothetical protein spyM18 1273 [Streptococcus pyogenes MGAS8232]; hypothetical protein complement(1102205..1102474) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110997 YP_002996844.1 CDS SDEG_1131 NC_012891.1 1102536 1102733 R similar to hypothetical protein MGAS10750 Spy1919 [bacteriophage 10750.4]; hypothetical protein complement(1102536..1102733) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110998 YP_002996845.1 CDS SDEG_1132 NC_012891.1 1102733 1103944 R similar to hypothetical protein SAK 0633 [Streptococcus agalactiae A909]; hypothetical protein complement(1102733..1103944) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110999 YP_002996846.1 CDS SDEG_1133 NC_012891.1 1103937 1105205 R similar to structural phage protein [Streptococcus pyogenes MGAS8232]; structural phage protein complement(1103937..1105205) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111000 YP_002996847.1 CDS SDEG_1134 NC_012891.1 1105202 1105558 R similar to hypothetical protein spyM18 1482 [Streptococcus pyogenes MGAS8232]; hypothetical protein complement(1105202..1105558) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111001 YP_002996848.1 CDS SDEG_1135 NC_012891.1 1105706 1106050 R similar to HNH endonuclease family protein [Streptococcus pyogenes MGAS5005]; hypothetical protein complement(1105706..1106050) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111002 YP_002996849.1 CDS SDEG_1136 NC_012891.1 1106158 1106577 R similar to hypothetical protein spyM18 1485 [Streptococcus pyogenes MGAS8232]; hypothetical protein complement(1106158..1106577) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111003 YP_002996850.1 CDS SDEG_1137 NC_012891.1 1106653 1106904 R similar to hypothetical protein SpyM3 1125 [Streptococcus pyogenes MGAS315]; hypothetical protein complement(1106653..1106904) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111004 YP_002996851.1 CDS SDEG_1138 NC_012891.1 1106918 1107187 R similar to phage protein [bacteriophage 10750.2]; phage protein complement(1106918..1107187) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111005 YP_002996852.1 CDS SDEG_1139 NC_012891.1 1107184 1107375 R similar to phage protein [bacteriophage 10750.1]; phage protein complement(1107184..1107375) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111006 YP_002996853.1 CDS SDEG_1140 NC_012891.1 1107362 1107874 R similar to phage protein [Streptococcus pyogenes MGAS5005]; phage protein complement(1107362..1107874) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111007 YP_002996854.1 CDS SDEG_1141 NC_012891.1 1107871 1108212 R similar to hypothetical protein spyM18 0734 [Streptococcus pyogenes MGAS8232]; hypothetical protein complement(1107871..1108212) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111008 YP_002996855.1 CDS SDEG_1142 NC_012891.1 1108387 1108554 R similar to phage protein [Streptococcus pyogenes MGAS5005]; phage protein complement(1108387..1108554) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111009 YP_002996856.1 CDS SDEG_1143 NC_012891.1 1108564 1109361 R similar to hypothetical protein spyM18 1494 [Streptococcus pyogenes MGAS8232]; hypothetical protein complement(1108564..1109361) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111010 YP_002996857.1 CDS SDEG_1144 NC_012891.1 1109354 1109554 R similar to hypothetical protein spyM18 0732 [Streptococcus pyogenes MGAS8232]; hypothetical protein complement(1109354..1109554) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111011 YP_002996858.1 CDS SDEG_1145 NC_012891.1 1109551 1110477 R similar to recT protein [Streptococcus pyogenes MGAS5005]; recT protein complement(1109551..1110477) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111012 YP_002996859.1 CDS SDEG_1146 NC_012891.1 1110638 1110844 R similar to hypothetical protein SPy 0956 [Streptococcus phage 370.3]; hypothetical protein complement(1110638..1110844) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111013 YP_002996860.1 CDS SDEG_1147 NC_012891.1 1110853 1110993 R similar to phage protein [Streptococcus pyogenes MGAS10270]; phage protein complement(1110853..1110993) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111014 YP_002996861.1 CDS SDEG_1148 NC_012891.1 1110990 1111223 R similar to hypothetical protein spyM18 1499 [Streptococcus pyogenes MGAS8232]; hypothetical protein complement(1110990..1111223) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111015 YP_002996862.1 CDS SDEG_1149 NC_012891.1 1111204 1111590 R similar to phage DNA replication protein [Streptococcus pyogenes str. Manfredo]; phage DNA replication protein complement(1111204..1111590) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111016 YP_002996863.1 CDS SDEG_1150 NC_012891.1 1111729 1111980 R similar to phage replication protein [Streptococcus pyogenes MGAS5005]; phage replication protein complement(1111729..1111980) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111017 YP_002996864.1 CDS SDEG_1151 NC_012891.1 1112080 1112265 R similar to hypothetical protein SPy 0952 [Streptococcus phage 370.3]; hypothetical protein complement(1112080..1112265) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111018 YP_002996865.1 CDS SDEG_1152 NC_012891.1 1112267 1112557 R similar to phage protein [Streptococcus pyogenes MGAS6180]; phage protein complement(1112267..1112557) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111019 YP_002996866.1 CDS SDEG_1153 NC_012891.1 1112847 1113050 R similar to unknown phage protein [Streptococcus pyogenes MGAS10394]; phage protein complement(1112847..1113050) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111020 YP_002996867.1 CDS SDEG_1154 NC_012891.1 1113108 1113521 D similar to phage protein [Streptococcus pyogenes phage 5005.3]; phage protein 1113108..1113521 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111021 YP_002996868.1 CDS SDEG_1155 NC_012891.1 1113694 1113909 R similar to hypothetical protein SpyM50635 [Streptococcus pyogenes str. Manfredo]; hypothetical protein complement(1113694..1113909) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111022 YP_002996869.1 CDS SDEG_1156 NC_012891.1 1114216 1114566 D similar to phage DNA-binding protein [Streptococcus pyogenes str. Manfredo]; phage DNA-binding protein 1114216..1114566 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111023 YP_002996870.1 CDS SDEG_1157 NC_012891.1 1114569 1114955 D similar to hypothetical protein SpyM50633 [Streptococcus pyogenes str. Manfredo]; hypothetical protein 1114569..1114955 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111024 YP_002996871.1 CDS SDEG_1158 NC_012891.1 1114966 1115388 D similar to hypothetical protein CGSSp6BS73 08144 [Streptococcus pneumoniae SP6-BS73]; hypothetical protein 1114966..1115388 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111025 YP_002996872.1 CDS SDEG_1159 NC_012891.1 1115394 1115867 D similar to hypothetical protein CGSSp6BS73 08139 [Streptococcus pneumoniae SP6-BS73]; hypothetical protein 1115394..1115867 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111026 YP_002996873.1 CDS int NC_012891.1 1115991 1117079 D similar to integrase [Streptococcus pyogenes MGAS8232]; integrase 1115991..1117079 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111027 YP_002996874.1 CDS SDEG_1161 NC_012891.1 1117436 1118062 D similar to hypothetical protein M5005 Spy 1054 [Streptococcus pyogenes phage 5005.1]; hypothetical protein 1117436..1118062 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110869 YP_002996875.1 CDS SDEG_1162 NC_012891.1 1118158 1118592 R similar to transposase [Streptococcus pyogenes MGAS10394]; transposase complement(1118158..1118592) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111028 YP_002996876.1 CDS SDEG_1163 NC_012891.1 1118420 1119619 R similar to transposase; Phage-associated cell wall hydrolase [Streptococcus pyogenes MGAS10394]; transposase complement(1118420..1119619) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111029 YP_002996877.1 CDS rpsA NC_012891.1 1119925 1121130 R in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins; 30S ribosomal protein S1 complement(1119925..1121130) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111517 YP_002996879.1 CDS SDEG_1169 NC_012891.1 1121519 1121749 R similar to hypothetical cytosolic protein [Streptococcus pyogenes MGAS10750]; hypothetical protein complement(1121519..1121749) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111519 YP_002996880.1 CDS bcaT NC_012891.1 1121813 1122838 R catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids; branched-chain amino acid aminotransferase complement(1121813..1122838) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111520 YP_002996881.1 CDS SDEG_1171 NC_012891.1 1123037 1124047 D similar to transposase [Streptococcus pyogenes MGAS10394]; transposase 1123037..1124047 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112366 YP_002996882.1 CDS parC NC_012891.1 1124044 1126503 R decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling; DNA topoisomerase IV subunit A complement(1124044..1126503) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111521 YP_002996883.1 CDS SDEG_1173 NC_012891.1 1126700 1127518 R similar to hypothetical protein MGAS10270 Spy0770 [Streptococcus pyogenes MGAS10270]; hypothetical protein complement(1126700..1127518) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111751 YP_002996884.1 CDS parE NC_012891.1 1127585 1129537 R decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling; DNA topoisomerase IV subunit B complement(1127585..1129537) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111522 YP_002996885.1 CDS SDEG_1175 NC_012891.1 1129669 1130310 D involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsX; glycerol-3-phosphate acyltransferase PlsY 1129669..1130310 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111752 YP_002996886.1 CDS pyrC NC_012891.1 1130370 1131641 R catalyzes the formation of N-carbamoyl-L-aspartate from (S)-dihydroorotate in pyrimidine biosynthesis; dihydroorotase complement(1130370..1131641) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111523 YP_002996887.1 CDS ung NC_012891.1 1131773 1132426 R Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine; uracil-DNA glycosylase complement(1131773..1132426) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111339 YP_002996888.1 CDS SDEG_1178 NC_012891.1 1132559 1133209 R similar to cystine transport system permease protein [Streptococcus pyogenes MGAS5005]; cystine transport system permease complement(1132559..1133209) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111942 YP_002996889.1 CDS SDEG_1179 NC_012891.1 1133238 1134137 R similar to cystine-binding protein [Streptococcus pyogenes MGAS10394]; cystine-binding protein complement(1133238..1134137) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111524 YP_002996890.1 CDS amiC NC_012891.1 1134219 1135673 R catalyzes the hydrolysis of a monocarboxylic acid amid to form a monocarboxylate and ammonia; amidase complement(1134219..1135673) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111525 YP_002996891.1 CDS SDEG_1181 NC_012891.1 1135852 1136649 R similar to transposase IS861 orfB [Streptococcus equi subsp. zooepidemicus MGCS10565]; transposase IS861 orfB complement(1135852..1136649) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112321 YP_002996892.1 CDS SDEG_1182 NC_012891.1 1136685 1137215 R similar to transposase IS861 orfA [Streptococcus equi subsp. zooepidemicus MGCS10565]; transposase IS861 orfA complement(1136685..1137215) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111526 YP_002996893.1 CDS SDEG_1183 NC_012891.1 1137270 1138016 R similar to acetyltransferase GNAT family [Streptococcus equi subsp. zooepidemicus MGCS10565]; GNAT family acetyltransferase complement(1137270..1138016) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111527 YP_002996894.1 CDS pyrE NC_012891.1 1138057 1138686 R similar to Orotate phosphoribosyltransferase [Streptococcus thermophilus LMD-9]; orotate phosphoribosyl transferase complement(1138057..1138686) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111528 YP_002996895.1 CDS pyrF NC_012891.1 1138747 1139439 R type 1 subfamily; involved in last step of pyrimidine biosynthesis; converts orotidine 5'-phosphate to UMP and carbon dioxide; OMP decarboxylase; OMPDCase; OMPdecase; orotidine 5'-phosphate decarboxylase complement(1138747..1139439) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111341 YP_002996896.1 CDS SDEG_1186 NC_012891.1 1139651 1140199 R similar to hypothetical protein M5005 Spy 0702 [Streptococcus pyogenes MGAS5005]; hypothetical protein complement(1139651..1140199) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111342 YP_002996897.1 CDS cpsY NC_012891.1 1140423 1141340 D similar to transcriptional regulators LysR family [Streptococcus pyogenes MGAS2096]; LysR family transcriptional regulator 1140423..1141340 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111529 YP_002996898.1 CDS cpsX NC_012891.1 1141422 1142198 R similar to attenuator of transcription LytR family regulator [Streptococcus pyogenes MGAS6180]; attenuator of transcription, LytR family regulator complement(1141422..1142198) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111649 YP_002996899.1 CDS deoD NC_012891.1 1142185 1142898 R catalyzes the reversible phosphorolysis of ribonucleosides and 2'- deoxyribonucleosides to the free base and (2'-deoxy)ribose-1- phosphate; purine nucleoside phosphorylase complement(1142185..1142898) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111648 YP_002996900.1 CDS punA NC_012891.1 1143451 1144260 R catalyzes the formation of a purine and ribose phosphate from a purine nucleoside; in E. coli this enzyme functions in xanthosine degradation; purine nucleoside phosphorylase complement(1143451..1144260) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111669 YP_002996901.1 CDS arsC NC_012891.1 1144244 1144690 R similar to arsenate reductase [Streptococcus pyogenes MGAS10750]; arsenate reductase complement(1144244..1144690) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111329 YP_002996902.1 CDS deoB NC_012891.1 1144703 1145914 R catalyzes the transfer of phosphate between the C1 and C5 carbons of pentose; phosphopentomutase complement(1144703..1145914) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112344 YP_002996903.1 CDS rpiA NC_012891.1 1145993 1146676 R Catalyzes D-ribose 5-phosphate --> D-ribulose 5-phosphate in the nonoxidative branch of the pentose phosphate pathway; ribose-5-phosphate isomerase A complement(1145993..1146676) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111667 YP_002996904.1 CDS trmE NC_012891.1 1146818 1148194 D in Escherichia coli this protein is involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2-thiouridine, which is found in the wobble position of some tRNAs and affects ribosomal frameshifting; shows potassium-dependent dimerization and GTP hydrolysis; also involved in regulation of glutamate-dependent acid resistance and activation of gadE; tRNA modification GTPase TrmE 1146818..1148194 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111057 YP_002996905.1 CDS SDEG_1195 NC_012891.1 1148262 1149671 R divalent metal ion-dependent extracellular dipeptidase; able to hydrolyze a broad range of dipeptides but no tri-, tetra-, or larger oligopeptides; differences in the amino acid specificity of the cleavage site varies between species; similar to succinyl-diaminopimelate desuccinylases; dipeptidase PepV complement(1148262..1149671) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111927 YP_002996906.1 CDS SDEG_1196 NC_012891.1 1149849 1150451 R similar to NAD(P)H-dependent quinone reductase [Streptococcus pyogenes MGAS6180]; NAD(P)H-dependent quinone reductase complement(1149849..1150451) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111530 YP_002996907.1 CDS SDEG_1197 NC_012891.1 1150764 1151108 D similar to pyruvate oxidase or other thiamine pyrophosphate-requiring enzyme [Lactobacillus casei ATCC 334]; pyruvate oxidase or other thiamine pyrophosphate-requiring enzyme 1150764..1151108 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111531 YP_002996908.1 CDS SDEG_1198 NC_012891.1 1150933 1151835 D probable ORF of N-terminal portion of pyruvate oxidase [Lactobacillus paracasei] resulted from mutation by unknown reason; pyruvate oxidase 1150933..1151835 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111532 YP_002996909.1 CDS SDEG_1199 NC_012891.1 1152006 1152422 D probable ORF of C-terminal portion of pyruvate oxidase [Lactobacillus paracasei] resulted from mutation by unknown reason; pyruvate oxidase 1152006..1152422 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111533 YP_002996910.1 CDS uvrC NC_012891.1 1152475 1154259 R The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision; excinuclease ABC subunit C complement(1152475..1154259) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111534 YP_002996911.1 CDS ybjI NC_012891.1 1154389 1154538 R similar to phosphatase YbjI [Escherichia coli HS]; phosphatase complement(1154389..1154538) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111946 YP_002996912.1 CDS gabD NC_012891.1 1154594 1155973 R similar to succinate-semialdehyde dehydrogenase [NADP+] [Streptococcus pyogenes MGAS10394]; succinate-semialdehyde dehydrogenase complement(1154594..1155973) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111959 YP_002996913.1 CDS SDEG_1203 NC_012891.1 1156047 1156754 R similar to hydrolase HAD superfamily [Streptococcus pyogenes MGAS5005]; HAD superfamily hydrolase complement(1156047..1156754) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111982 YP_002996914.1 CDS SDEG_1204 NC_012891.1 1156924 1157244 D similar to hypothetical protein RUMTOR 00521 [Ruminococcus torques ATCC 27756]; hypothetical protein 1156924..1157244 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111535 YP_002996915.1 CDS SDEG_1205 NC_012891.1 1157306 1158301 D similar to permease [Campylobacter hominis ATCC BAA-381]; permease 1157306..1158301 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111536 YP_002996916.1 CDS SDEG_1206 NC_012891.1 1158314 1158568 D similar to hypothetical protein CLORAM 03030 [Clostridium ramosum DSM 1402]; hypothetical protein 1158314..1158568 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111537 YP_002996917.1 CDS SDEG_1208 NC_012891.1 1159571 1160077 R similar to hypothetical protein SGO 0826 [Streptococcus gordonii str. Challis substr. CH1]; hypothetical protein complement(1159571..1160077) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111539 YP_002996918.1 CDS SDEG_1209 NC_012891.1 1160173 1161222 R similar to iron(III)-binding protein [Streptococcus pyogenes MGAS6180]; iron(III)-binding protein complement(1160173..1161222) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111540 YP_002996919.1 CDS yesN NC_012891.1 1161209 1162003 R similar to two-component response regulator YesN [Streptococcus pyogenes MGAS10394]; two-component response regulator YesN complement(1161209..1162003) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111541 YP_002996920.1 CDS yesM NC_012891.1 1162007 1163656 R similar to two-component sensor kinase YesM [Streptococcus pyogenes MGAS10394]; two-component sensor kinase YesM complement(1162007..1163656) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111963 YP_002996921.1 CDS ptsD NC_012891.1 1163802 1164629 R similar to PTS system mannose/fructose family IID component [Streptococcus pyogenes MGAS6180]; PTS system mannose/fructose family transporter subunit IID complement(1163802..1164629) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111960 YP_002996922.1 CDS ptsC NC_012891.1 1164626 1165435 R similar to PTS system mannose/fructose family IIC component [Streptococcus pyogenes MGAS2096]; PTS system mannose/fructose family transporter subunit IIC complement(1164626..1165435) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111325 YP_002996923.1 CDS ptsB NC_012891.1 1165451 1165942 R similar to PTS system mannose/fructose family IIB component [Streptococcus pyogenes MGAS10750]; PTS system mannose/fructose family transporter subunit IIB complement(1165451..1165942) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111324 YP_002996924.1 CDS SDEG_1215 NC_012891.1 1165961 1166386 R similar to PTS system mannose/fructose family IIA component [Streptococcus pyogenes MGAS2096]; PTS system mannose/fructose family transporter subunit IIA complement(1165961..1166386) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111323 YP_002996925.1 CDS SDEG_1216 NC_012891.1 1166593 1167612 R similar to hypothetical membrane spanning protein [Streptococcus pyogenes MGAS10394]; hypothetical protein complement(1166593..1167612) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111542 YP_002996926.1 CDS SDEG_1217 NC_012891.1 1167723 1168892 R similar to hypothetical protein STRINF 01596 [Streptococcus infantarius subsp. infantarius ATCC BAA-102]; hypothetical protein complement(1167723..1168892) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111543 YP_002996927.1 CDS spiA NC_012891.1 1169082 1169378 R similar to SpiA (OrfY protein) ( sakacin P immunity protein) [Lactobacillus casei BL23]; sakacin P immunityprotein complement(1169082..1169378) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111544 YP_002996928.1 CDS SDEG_1219 NC_012891.1 1169378 1169656 R similar to hypothetical protein STRINF 01005 [Streptococcus infantarius subsp. infantarius ATCC BAA-102]; hypothetical protein complement(1169378..1169656) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110498 YP_002996929.1 CDS SDEG_1220 NC_012891.1 1169816 1170466 R similar to hypothetical protein STRINF 01223 [Streptococcus infantarius subsp. infantarius ATCC BAA-102]; hypothetical protein complement(1169816..1170466) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111545 YP_002996930.1 CDS msrB NC_012891.1 1170479 1170916 R this stereospecific enzymes reduces the R isomer of methionine sulfoxide while MsrA reduces the S form; provides protection against oxidative stress; methionine sulfoxide reductase B complement(1170479..1170916) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111546 YP_002996931.1 CDS lepA NC_012891.1 1171092 1172924 R binds to the ribosome on the universally-conserved alpha-sarcin loop; GTP-binding protein LepA complement(1171092..1172924) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110946 YP_002996932.1 CDS ndk NC_012891.1 1172994 1173452 R catalyzes the formation of nucleoside triphosphate from ATP and nucleoside diphosphate; nucleoside diphosphate kinase complement(1172994..1173452) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110892 YP_002996933.1 CDS SDEG_1224 NC_012891.1 1173530 1173742 D similar to hypothetical protein SAM 0929 [Streptococcus agalactiae CJB111]; hypothetical protein 1173530..1173742 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111709 YP_002996934.1 CDS SDEG_1225 NC_012891.1 1173618 1173821 D similar to hypothetical protein SAM 0929 [Streptococcus agalactiae CJB111]; hypothetical protein 1173618..1173821 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111547 YP_002996935.1 CDS SDEG_1226 NC_012891.1 1173947 1174408 D similar to conserved hypothetical protein [Streptococcus agalactiae 18RS21]; hypothetical protein 1173947..1174408 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111548 YP_002996936.1 CDS SDEG_1227 NC_012891.1 1174478 1174750 D similar to conserved hypothetical protein [Streptococcus agalactiae H36B]; hypothetical protein 1174478..1174750 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111549 YP_002996937.1 CDS SDEG_1228 NC_012891.1 1174896 1175624 R similar to hypothetical protein MGAS2096 Spy0846 [Streptococcus pyogenes MGAS2096]; hypothetical protein complement(1174896..1175624) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111550 YP_002996938.1 CDS SDEG_1229 NC_012891.1 1175548 1175889 R similar to hypothetical protein SPs1174 [Streptococcus pyogenes SSI-1]; hypothetical protein complement(1175548..1175889) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111551 YP_002996939.1 CDS SDEG_1230 NC_012891.1 1175886 1176755 R similar to hypothetical cytosolic protein [Streptococcus pyogenes MGAS5005]; hypothetical protein complement(1175886..1176755) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111552 YP_002996940.1 CDS SDEG_1231 NC_012891.1 1176755 1180870 R similar to hypothetical cytosolic protein [Streptococcus pyogenes MGAS10750]; hypothetical protein complement(1176755..1180870) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111553 YP_002996941.1 CDS SDEG_1232 NC_012891.1 1180894 1181010 R similar to hypothetical protein MGAS9429 Spy0884 [Streptococcus pyogenes MGAS9429]; hypothetical protein complement(1180894..1181010) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111554 YP_002996942.1 CDS SDEG_1233 NC_012891.1 1181346 1181987 R similar to hypothetical membrane spanning protein [Streptococcus pyogenes MGAS10270]; hypothetical protein complement(1181346..1181987) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111555 YP_002996943.1 CDS SDEG_1234 NC_012891.1 1181975 1182739 R similar to haloacid dehalogenase-like hydrolase [Streptococcus pyogenes MGAS2096]; haloacid dehalogenase-like hydrolase complement(1181975..1182739) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111556 YP_002996944.1 CDS SDEG_1235 NC_012891.1 1182739 1183491 R similar to acyl-acyl carrier protein thioesterase [Streptococcus pyogenes MGAS5005]; acyl-acyl carrier protein thioesterase complement(1182739..1183491) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111557 YP_002996945.1 CDS hemN NC_012891.1 1183501 1184631 R catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III; coproporphyrinogen III oxidase complement(1183501..1184631) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111558 YP_002996946.1 CDS SDEG_1237 NC_012891.1 1184693 1185334 R similar to hypothetical protein SpyM50995 [Streptococcus pyogenes str. Manfredo]; hypothetical protein complement(1184693..1185334) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112029 YP_002996947.1 CDS glmM NC_012891.1 1185458 1186813 R catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; phosphoglucosamine mutase complement(1185458..1186813) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111559 YP_002996948.1 CDS SDEG_1239 NC_012891.1 1186867 1187823 R similar to hypothetical membrane associated protein [Streptococcus pyogenes MGAS6180]; hypothetical protein complement(1186867..1187823) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111886 YP_002996949.1 CDS SDEG_1240 NC_012891.1 1187820 1188671 R similar to hypothetical protein SpyM50998 [Streptococcus pyogenes str. Manfredo]; hypothetical protein complement(1187820..1188671) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111560 YP_002996950.1 CDS SDEG_1241 NC_012891.1 1188775 1190118 D similar to UDP-N-acetylmuramoylalanyl-D-glutamate- 2,6-diaminopimelate ligase [Streptococcus pyogenes MGAS10270]; UDP-N-acetylmuramoylalanyl-D-glutamate-2,6- diaminopimelate ligase 1188775..1190118 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111561 YP_002996951.1 CDS SDEG_1242 NC_012891.1 1190118 1190909 D similar to CobB/CobQ-like glutamine amidotransferase domain [Streptococcus pyogenes MGAS2096]; CobB/CobQ-like glutamine amidotransferase domain 1190118..1190909 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111562 YP_002996952.1 CDS lplB NC_012891.1 1191014 1192003 R similar to lipoate-protein ligase [Streptococcus pyogenes M1 GAS]; lipoate-protein ligase complement(1191014..1192003) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111563 YP_002996953.1 CDS SDEG_1244 NC_012891.1 1192086 1193249 R similar to hypothetical membrane associated protein [Streptococcus equi subsp. zooepidemicus MGCS10565]; hypothetical protein complement(1192086..1193249) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110907 YP_002996954.1 CDS SDEG_1245 NC_012891.1 1193195 1193509 R similar to transcriptional regulator PadR family [Streptococcus pyogenes MGAS10394]; PadR family transcriptional regulator complement(1193195..1193509) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111564 YP_002996955.1 CDS acoL NC_012891.1 1193739 1195502 R similar to dihydrolipoamide dehydrogenase [Streptococcus pyogenes MGAS10394]; dihydrolipoamide dehydrogenase complement(1193739..1195502) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111565 YP_002996956.1 CDS SDEG_1247 NC_012891.1 1195535 1195774 D similar to hypothetical protein MGAS2096 Spy0827 [Streptococcus pyogenes MGAS2096]; hypothetical protein 1195535..1195774 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112302 YP_002996957.1 CDS acoC NC_012891.1 1195829 1197238 R similar to dihydrolipoamide acetyltransferase [Streptococcus pyogenes MGAS10394]; branched-chain alpha-keto acid dehydrogenase E2 subunit complement(1195829..1197238) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111566 YP_002996958.1 CDS acoB NC_012891.1 1197418 1198419 R similar to pyruvate dehydrogenase E1 component beta subunit [Streptococcus pyogenes MGAS10394]; pyruvate dehydrogenase E1 component subunit beta complement(1197418..1198419) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112301 YP_002996959.1 CDS acoA NC_012891.1 1198475 1199455 R similar to pyruvate dehydrogenase E1 component alpha subunit [Streptococcus pyogenes MGAS10394]; pyruvate dehydrogenase E1 component subunit alpha complement(1198475..1199455) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112300 YP_002996960.1 CDS SDEG_1251 NC_012891.1 1199728 1201635 R similar to ABC transporter ATP-binding protein [Streptococcus pyogenes MGAS5005]; ABC transporter ATP-binding protein complement(1199728..1201635) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112299 YP_002996961.1 CDS SDEG_1252 NC_012891.1 1201714 1202007 R similar to hypothetical protein SpyoM01000868 [Streptococcus pyogenes M49 591]; hypothetical protein complement(1201714..1202007) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111567 YP_002996962.1 CDS estA NC_012891.1 1202037 1202822 R similar to acetyl esterase [Streptococcus pyogenes MGAS6180]; acetyl esterase complement(1202037..1202822) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111568 YP_002996963.1 CDS SDEG_1254 NC_012891.1 1202955 1204616 R similar to Zn-dependent hydrolase [Streptococcus pyogenes MGAS10394]; Zn-dependent hydrolase complement(1202955..1204616) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111873 YP_002996964.1 CDS SDEG_1255 NC_012891.1 1204828 1205586 R similar to ABC transporter ATP-binding protein [Streptococcus pyogenes MGAS10394]; ABC transporter ATP-binding protein complement(1204828..1205586) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111569 YP_002996965.1 CDS SDEG_1256 NC_012891.1 1205583 1206452 R similar to ABC transporter permease protein [Streptococcus pyogenes str. Manfredo]; ABC transporter permease complement(1205583..1206452) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111570 YP_002996966.1 CDS SDEG_1257 NC_012891.1 1206470 1207465 R similar to ABC transporter substrate-binding protein [Streptococcus pyogenes MGAS10394]; ABC transporter substrate-binding protein complement(1206470..1207465) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111571 YP_002996967.1 CDS SDEG_1258 NC_012891.1 1207928 1209205 R similar to hypothetical protein gbs1118 [Streptococcus agalactiae NEM316]; hypothetical protein complement(1207928..1209205) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111572 YP_002996968.1 CDS aphA NC_012891.1 1211214 1211951 R Class B; non-specific; catalyzes the dephosphorylation of organic phosphomonoesters; also has phosphotransferase activity; acid phosphatase/phosphotransferase complement(1211214..1211951) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111573 YP_002996969.1 CDS SDEG_1260 NC_012891.1 1212071 1212292 R similar to hypothetical protein SAG0634 [Streptococcus agalactiae 2603V/R]; hypothetical protein complement(1212071..1212292) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111574 YP_002996970.1 CDS SDEG_1261 NC_012891.1 1212461 1212751 D similar to ISSag4 transposase orfA [Streptococcus agalactiae A909]; ISSag4, transposase orfA 1212461..1212751 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111575 YP_002996971.1 CDS SDEG_1262 NC_012891.1 1213155 1213496 R similar to hypothetical protein gbs1153 [Streptococcus agalactiae NEM316]; hypothetical protein complement(1213155..1213496) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111576 YP_002996972.1 CDS fbp NC_012891.1 1213632 1215326 D similar to fibronectin-binding protein [Streptococcus pyogenes MGAS10270]; fibronectin-binding protein 1213632..1215326 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111577 YP_002996973.1 CDS SDEG_1264 NC_012891.1 1215389 1216654 R similar to tetratricopeptide repeat family protein [Streptococcus pyogenes MGAS10394]; hypothetical protein complement(1215389..1216654) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111885 YP_002996974.1 CDS SDEG_1265 NC_012891.1 1216626 1217807 R similar to hypothetical membrane spanning protein [Streptococcus pyogenes MGAS5005]; hypothetical protein complement(1216626..1217807) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111578 YP_002996975.1 CDS SDEG_1266 NC_012891.1 1217856 1218335 R similar to 7,8-dihydro-8-oxoguanine-triphosphatase [Streptococcus pyogenes MGAS10750]; 7,8-dihydro-8-oxoguanine-triphosphatase complement(1217856..1218335) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111579 YP_002996976.1 CDS SDEG_1267 NC_012891.1 1218531 1218722 D similar to hypothetical protein STER 0685 [Streptococcus thermophilus LMD-9]; hypothetical protein 1218531..1218722 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111580 YP_002996977.1 CDS SDEG_1268 NC_012891.1 1218810 1219244 R similar to hypothetical protein CLORAM 02318 [Clostridium ramosum DSM 1402]; hypothetical protein complement(1218810..1219244) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111581 YP_002996978.1 CDS cpsFQ NC_012891.1 1219695 1220747 R similar to dTDP-glucose 4,6-dehydratase [Streptococcus pyogenes MGAS10394]; dTDP-glucose 4,6-dehydratase complement(1219695..1220747) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111582 YP_002996979.1 CDS cpsFP NC_012891.1 1220982 1221575 R similar to dTDP-4-dehydrorhamnose 3,5-epimerase [Streptococcus pyogenes MGAS6180]; dTDP-4-dehydrorhamnose 3,5-epimerase complement(1220982..1221575) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111647 YP_002996980.1 CDS cpsFO NC_012891.1 1221575 1222444 R similar to glucose-1-phosphate thymidyl transferase [Streptococcus pyogenes str. Manfredo]; glucose-1-phosphate thymidylyltransferase complement(1221575..1222444) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111646 YP_002996981.1 CDS SDEG_1272 NC_012891.1 1222502 1223608 R similar to glycine/D-amino acid oxidases family [Streptococcus pyogenes MGAS10750]; glycine/D-amino acid oxidase complement(1222502..1223608) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111645 YP_002996982.1 CDS SDEG_1273 NC_012891.1 1223618 1224439 R similar to hypothetical protein STRINF 01350 [Streptococcus infantarius subsp. infantarius ATCC BAA-102]; hypothetical protein complement(1223618..1224439) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111583 YP_002996983.1 CDS SDEG_1274 NC_012891.1 1224457 1225245 R similar to NIF3 (NGG1p interacting factor 3) family protein [Streptococcus pyogenes str. Manfredo]; NIF3 (NGG1p interacting factor 3) family protein complement(1224457..1225245) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111584 YP_002996984.1 CDS SDEG_1275 NC_012891.1 1225235 1225921 R similar to hypothetical cytosolic protein [Streptococcus pyogenes MGAS2096]; hypothetical protein complement(1225235..1225921) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111585 YP_002996985.1 CDS nth NC_012891.1 1226002 1226670 R similar to endonuclease III [Streptococcus pyogenes MGAS5005]; endonuclease III complement(1226002..1226670) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111586 YP_002996986.1 CDS dnaD NC_012891.1 1226655 1227338 R similar to DNA replication protein [Streptococcus pyogenes MGAS10394]; DNA replication protein complement(1226655..1227338) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111724 YP_002996987.1 CDS apt NC_012891.1 1227556 1228074 R catalyzes a salvage reaction resulting in the formation of AMP which is metabolically less costly than a de novo synthesis; adenine phosphoribosyltransferase complement(1227556..1228074) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111844 YP_002996988.1 CDS recJ NC_012891.1 1228222 1230429 R similar to single-stranded-DNA-specific exonuclease [Streptococcus pyogenes MGAS5005]; single-stranded-DNA-specific exonuclease complement(1228222..1230429) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112329 YP_002996989.1 CDS SDEG_1280 NC_012891.1 1230426 1231190 R similar to short chain dehydrogenase [Streptococcus pyogenes MGAS10394]; short chain dehydrogenase complement(1230426..1231190) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111035 YP_002996990.1 CDS elaC NC_012891.1 1231190 1232119 R member of metallo-beta-lactamase family; the purified enzyme from Escherichia coli forms dimeric zinc phosphodiesterase; in Bacillus subtilis this protein is a 3'-tRNA processing endoribonuclease and is essential while in Escherichia coli it is not; associates with two zinc ions; ribonuclease Z complement(1231190..1232119) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111587 YP_002996991.1 CDS SDEG_1282 NC_012891.1 1232134 1232769 R similar to hypothetical protein spyM18 0980 [Streptococcus pyogenes MGAS8232]; hypothetical protein complement(1232134..1232769) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111868 YP_002996992.1 CDS hflX NC_012891.1 1232762 1234012 R similar to HflX [Streptococcus pyogenes MGAS10394]; GTP-binding protein HflX complement(1232762..1234012) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111588 YP_002996993.1 CDS miaA NC_012891.1 1234088 1234972 R IPP transferase; isopentenyltransferase; involved in tRNA modification; in Escherichia coli this enzyme catalyzes the addition of a delta2-isopentenyl group from dimethylallyl diphosphate to the N6-nitrogen of adenosine adjacent to the anticodon of tRNA species that read codons starting with uracil; further tRNA modifications may occur; mutations in miaA result in defects in translation efficiency and fidelity; tRNA delta(2)-isopentenylpyrophosphate transferase complement(1234088..1234972) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112030 YP_002996994.1 CDS SDEG_1285 NC_012891.1 1235105 1235281 D similar to hypothetical protein M6 Spy0747 [Streptococcus pyogenes MGAS10394]; hypothetical protein 1235105..1235281 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110938 YP_002996995.1 CDS SDEG_1286 NC_012891.1 1235386 1236327 R similar to exfoliative toxin [Streptococcus pyogenes MGAS10394]; exfoliative toxin complement(1235386..1236327) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111589 YP_002996996.1 CDS SDEG_1287 NC_012891.1 1236486 1237094 R similar to glutathione S-transferase [Streptococcus pyogenes MGAS10750]; glutathione S-transferase complement(1236486..1237094) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111590 YP_002996997.1 CDS SDEG_1288 NC_012891.1 1237173 1237658 R similar to hypothetical protein Sez 1253 [Streptococcus equi subsp. zooepidemicus MGCS10565]; hypothetical protein complement(1237173..1237658) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111591 YP_002996998.1 CDS SDEG_1289 NC_012891.1 1237878 1238864 R similar to hypothetical protein SpyM51090 [Streptococcus pyogenes str. Manfredo]; hypothetical protein complement(1237878..1238864) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111592 YP_002996999.1 CDS SDEG_1290 NC_012891.1 1239059 1239361 D similar to hypothetical protein Spy49 0725c [Streptococcus pyogenes NZ131]; hypothetical protein 1239059..1239361 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111593 YP_002997000.1 CDS SDEG_1291 NC_012891.1 1239426 1239980 R similar to NADPH-dependent FMN reductase [Bacillus coagulans 36D1]; NADPH-dependent FMN reductase complement(1239426..1239980) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111594 YP_002997001.1 CDS glgP NC_012891.1 1240217 1242481 R similar to glycogen phosphorylase [Streptococcus pyogenes MGAS10394]; glycogen phosphorylase complement(1240217..1242481) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111595 YP_002997002.1 CDS malQ NC_012891.1 1242512 1244008 R amylomaltase; acts to release glucose from maltodextrins; 4-alpha-glucanotransferase complement(1242512..1244008) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112000 YP_002997003.1 CDS malR NC_012891.1 1244127 1245146 R similar to maltose operon transcriptional repressor MalR [Streptococcus equi subsp. zooepidemicus MGCS10565]; maltose operon transcriptional repressor complement(1244127..1245146) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110924 YP_002997004.1 CDS SDEG_1295 NC_012891.1 1245384 1246412 D similar to transposase [Streptococcus pyogenes MGAS10270]; transposase 1245384..1246412 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110925 YP_002997005.1 CDS malE NC_012891.1 1246568 1247821 D similar to maltose/maltodextrin-binding protein [Streptococcus pyogenes MGAS10750]; maltose/maltodextrin-binding protein 1246568..1247821 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111596 YP_002997006.1 CDS malF NC_012891.1 1248102 1249463 D similar to maltose/maltodextrin ABC transport system (permease) [Streptococcus pyogenes M1 GAS]; maltose/maltodextrin ABC transportsystem (permease) 1248102..1249463 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110920 YP_002997007.1 CDS malG NC_012891.1 1249463 1250299 D similar to MalG [Streptococcus pyogenes MGAS10394]; maltose transport system permease 1249463..1250299 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110921 YP_002997008.1 CDS SDEG_1299 NC_012891.1 1250472 1251269 D similar to transcriptional regulator, LacI family [Streptococcus pyogenes MGAS10270]; LacI family transcriptional regulator 1250472..1251269 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110922 YP_002997009.1 CDS malA NC_012891.1 1251343 1252170 R similar to maltodextrose utilization protein malA [Streptococcus pyogenes MGAS10270]; maltodextrose utilization protein complement(1251343..1252170) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111111 YP_002997010.1 CDS malD NC_012891.1 1252192 1253052 R similar to maltodextrin transport system permease protein malD [Streptococcus pyogenes MGAS10270]; maltodextrin transport system permease complement(1252192..1253052) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110916 YP_002997011.1 CDS malC NC_012891.1 1253052 1253180 R similar to maltose transport system permease protein [Streptococcus pyogenes MGAS5005]; maltose transport system permease complement(1253052..1253180) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110919 YP_002997012.1 CDS malC NC_012891.1 1253284 1254357 R similar to maltodextrin transport system permease protein malC [Streptococcus pyogenes MGAS10270]; maltodextrin transport system permease complement(1253284..1254357) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110917 YP_002997013.1 CDS amyB NC_012891.1 1254480 1256183 R similar to neopullulanase/cyclomaltodextrinase/ maltogenic alpha-amylase [Streptococcus pyogenes MGAS5005]; neopullulanase complement(1254480..1256183) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110918 YP_002997014.1 CDS malX NC_012891.1 1256348 1257601 R similar to maltose/maltodextrin-binding protein [Streptococcus pyogenes MGAS6180]; maltose/maltodextrin-binding protein complement(1256348..1257601) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112323 YP_002997015.1 CDS dltD NC_012891.1 1258005 1259261 R similar to secreted protein DltD [Streptococcus pyogenes MGAS315]; hypothetical protein complement(1258005..1259261) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110926 YP_002997016.1 CDS dltC NC_012891.1 1259254 1259493 R D-alanyl carrier protein subunit; involved in the incorporation of D-alanine into membrane-associated D-alanyl-lipoteichoic acid; D-alanyl carrier protein is the acceptor of activated D-alanine which it donates to a membrane acceptor(D-alanyl transferase) for incorporation into membrane lipoteichoic acid; D-alanine--poly(phosphoribitol) ligase subunit 2 complement(1259254..1259493) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111841 YP_002997017.1 CDS dltB NC_012891.1 1259511 1260767 R similar to DltB [Streptococcus pyogenes MGAS10394]; D-alanyl transfer protein complement(1259511..1260767) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111840 YP_002997018.1 CDS dltA NC_012891.1 1260764 1262302 R transfers D-alanine to the D-alanyl carrier protein during the incorporation of D-alanine into lipoteichoic acid; D-alanine--poly(phosphoribitol) ligase subunit 1 complement(1260764..1262302) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111677 YP_002997019.1 CDS SDEG_1310 NC_012891.1 1262314 1262457 R similar to hypothetical protein spyM18 1325 [Streptococcus pyogenes MGAS8232]; hypothetical protein complement(1262314..1262457) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111676 YP_002997020.1 CDS uvrB NC_012891.1 1262710 1264701 R The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion; excinuclease ABC subunit B complement(1262710..1264701) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111112 YP_002997021.1 CDS glnH NC_012891.1 1264888 1267065 D similar to glutamine-binding protein/glutamine transport system permease protein glnP [Streptococcus pyogenes MGAS10270]; glutamine-binding protein/glutamine transportsystem permease 1264888..1267065 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111945 YP_002997022.1 CDS glnQ.2 NC_012891.1 1267065 1267805 D similar to glutamine transport ATP-binding protein [Streptococcus pyogenes MGAS5005]; glutamine transport ATP-binding protein 1267065..1267805 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112003 YP_002997023.1 CDS SDEG_1314 NC_012891.1 1268107 1268568 D similar to nicotinamide mononucleotide transporter [Streptococcus pyogenes MGAS6180]; nicotinamide mononucleotide transporter 1268107..1268568 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112005 YP_002997024.1 CDS obgE NC_012891.1 1268792 1270105 R essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication; GTPase ObgE complement(1268792..1270105) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111113 YP_002997025.1 CDS SDEG_1316 NC_012891.1 1270160 1270288 R similar to hypothetical protein MGAS2096 Spy1090 [Streptococcus pyogenes MGAS2096]; hypothetical protein complement(1270160..1270288) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111731 YP_002997026.1 CDS pepS NC_012891.1 1270465 1271706 D similar to aminopeptidase PepS [Streptococcus equi subsp. zooepidemicus MGCS10565]; aminopeptidase 1270465..1271706 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111114 YP_002997027.1 CDS SDEG_1318 NC_012891.1 1271766 1272683 D similar to hypothetical protein ANACAC 02747 [anaerostipes caccae DSM 14662]; hypothetical protein 1271766..1272683 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111279 YP_002997028.1 CDS rsuA NC_012891.1 1272734 1273471 R similar to ribosomal small subunit pseudouridine synthase A [Streptococcus pyogenes MGAS5005]; ribosomal small subunit pseudouridine synthaseA complement(1272734..1273471) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111115 YP_002997029.1 CDS SDEG_1320 NC_012891.1 1273581 1273946 D similar to hypothetical protein MGAS10750 Spy1192 [Streptococcus pyogenes MGAS10750]; hypothetical protein 1273581..1273946 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110450 YP_002997030.1 CDS SDEG_1321 NC_012891.1 1274045 1275265 R similar to transporter MFS superfamily [Streptococcus pyogenes MGAS5005]; MFS superfamily transporter complement(1274045..1275265) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111116 YP_002997031.1 CDS SDEG_1322 NC_012891.1 1275629 1277122 D similar to hypothetical cytosolic protein [Streptococcus pyogenes MGAS5005]; hypothetical protein 1275629..1277122 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111117 YP_002997032.1 CDS SDEG_1323 NC_012891.1 1277199 1277969 R similar to hypothetical protein SAG0689 [Streptococcus agalactiae 2603V/R]; hypothetical protein complement(1277199..1277969) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111118 YP_002997033.1 CDS SDEG_1324 NC_012891.1 1277966 1278622 R similar to ABC transporter ATP-binding protein [Streptococcus agalactiae 2603V/R]; ABC transporter ATP-binding protein complement(1277966..1278622) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111119 YP_002997034.1 CDS SDEG_1325 NC_012891.1 1278826 1279218 R similar to thioesterase superfamily protein [Streptococcus pyogenes MGAS2096]; thioesterase complement(1278826..1279218) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111120 YP_002997035.1 CDS SDEG_1326 NC_012891.1 1279300 1280094 R similar to uridine phosphorylase [Streptococcus thermophilus LMD-9]; uridine phosphorylase complement(1279300..1280094) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111121 YP_002997036.1 CDS SDEG_1327 NC_012891.1 1280241 1281080 R similar to YaeC family protein [Streptococcus agalactiae 2603V/R]; YaeC family protein complement(1280241..1281080) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111122 YP_002997037.1 CDS SDEG_1328 NC_012891.1 1281659 1281949 D similar to ISSdy1, transposase OrfA [Streptococcus agalactiae 515]; ISSdy1, transposase OrfA 1281659..1281949 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111123 YP_002997038.1 CDS SDEG_1329 NC_012891.1 1281985 1282764 D similar to ISSdy1, transposase OrfB [Streptococcus agalactiae 2603V/R]; ISSdy1, transposase OrfB 1281985..1282764 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111124 YP_002997039.1 CDS SDEG_1330 NC_012891.1 1282855 1283577 R similar to ATPase component of ABC transporters with duplicated ATPase domains [Streptococcus suis 98HAH33]; ABC transporter ATPase complement(1282855..1283577) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111125 YP_002997040.1 CDS SDEG_1331 NC_012891.1 1283607 1284233 R similar to ABC transporter ATP-binding protein [Streptococcus equi subsp.; hypothetical protein complement(1283607..1284233) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111126 YP_002997041.1 CDS SDEG_1332 NC_012891.1 1284257 1286038 R similar to ABC transporter ATP-binding protein/peptidase [Treponema denticola ATCC 35405]; ABC transporter ATP-binding protein/peptidase complement(1284257..1286038) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111127 YP_002997042.1 CDS SDEG_1333 NC_012891.1 1286136 1286828 R similar to hypothetical protein llmg 0328 [Lactococcus lactis subsp. cremoris MG1363]; hypothetical protein complement(1286136..1286828) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111128 YP_002997043.1 CDS SDEG_1334 NC_012891.1 1287230 1288102 D similar to transcriptional regulator PlcR [Streptococcus pneumoniae SP3-BS71]; transcriptional regulator PlcR 1287230..1288102 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111129 YP_002997044.1 CDS SDEG_1335 NC_012891.1 1288145 1289539 R similar to relaxase [Streptococcus macedonicus]; relaxase complement(1288145..1289539) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111130 YP_002997045.1 CDS SDEG_1336 NC_012891.1 1289576 1289890 D similar to transposase [Streptococcus pyogenes MGAS6180]; transposase 1289576..1289890 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111131 YP_002997046.1 CDS SDEG_1337 NC_012891.1 1289943 1290746 D similar to transposase [Streptococcus pyogenes MGAS10270]; transposase 1289943..1290746 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111132 YP_002997047.1 CDS SDEG_1338 NC_012891.1 1290778 1291107 R similar to hypothetical protein PEPMIC 00594 [Peptostreptococcus micros ATCC 33270]; hypothetical protein complement(1290778..1291107) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111133 YP_002997048.1 CDS SDEG_1339 NC_012891.1 1291182 1291346 R similar to hypothetical protein PEPMIC 00190 [Peptostreptococcus micros ATCC 33270]; hypothetical protein complement(1291182..1291346) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111134 YP_002997049.1 CDS SDEG_1340 NC_012891.1 1291439 1292212 R similar to hypothetical protein EUBDOL 02334 [Eubacterium dolichum DSM 3991]; hypothetical protein complement(1291439..1292212) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111135 YP_002997050.1 CDS SDEG_1341 NC_012891.1 1292370 1293854 R similar to hypothetical protein PEPMIC 00192 [Peptostreptococcus micros ATCC 33270]; hypothetical protein complement(1292370..1293854) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111136 YP_002997051.1 CDS SDEG_1342 NC_012891.1 1293933 1294052 R similar to hypothetical protein PEPMIC 00193 [Peptostreptococcus micros ATCC 33270]; hypothetical protein complement(1293933..1294052) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111137 YP_002997052.1 CDS SDEG_1343 NC_012891.1 1294095 1294415 R similar to hypothetical protein PEPMIC 00194 [Peptostreptococcus micros ATCC 33270]; hypothetical protein complement(1294095..1294415) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111138 YP_002997053.1 CDS SDEG_1344 NC_012891.1 1294488 1294685 R similar to hypothetical protein TDE2175 [Treponema denticola ATCC 35405]; hypothetical protein complement(1294488..1294685) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111139 YP_002997054.1 CDS SDEG_1345 NC_012891.1 1294765 1296603 R similar to site-specific recombinase [Treponema denticola ATCC 35405]; site-specific recombinase complement(1294765..1296603) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111140 YP_002997055.1 CDS SDEG_1346 NC_012891.1 1296654 1296992 R similar to hypothetical protein PEPMIC 00594 [Peptostreptococcus micros ATCC 33270]; hypothetical protein complement(1296654..1296992) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111141 YP_002997056.1 CDS SDEG_1347 NC_012891.1 1296989 1297474 R similar to hypothetical protein PEPMIC 00593 [Peptostreptococcus micros ATCC 33270]; hypothetical protein complement(1296989..1297474) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111142 YP_002997057.1 CDS SDEG_1348 NC_012891.1 1297471 1298322 R similar to hypothetical protein PEPMIC 00592 [Peptostreptococcus micros ATCC 33270]; hypothetical protein complement(1297471..1298322) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111143 YP_002997058.1 CDS SDEG_1349 NC_012891.1 1298319 1299098 R similar to hypothetical protein PEPMIC 00591 [Peptostreptococcus micros ATCC 33270]; hypothetical protein complement(1298319..1299098) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111144 YP_002997059.1 CDS SDEG_1350 NC_012891.1 1299629 1300990 R similar to hypothetical protein PEPMIC 00591 [Peptostreptococcus micros ATCC 33270]; hypothetical protein complement(1299629..1300990) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111145 YP_002997060.1 CDS SDEG_1351 NC_012891.1 1301076 1302548 R similar to PBP 5 synthesis repressor [Streptococcus pyogenes MGAS8232]; PBP 5 synthesis repressor complement(1301076..1302548) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111146 YP_002997061.1 CDS aroK NC_012891.1 1302779 1303270 R catalyzes the formation of shikimate 3-phosphate from shikimate in aromatic amino acid biosynthesis; shikimate kinase complement(1302779..1303270) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111147 YP_002997062.1 CDS SDEG_1353 NC_012891.1 1303263 1304555 R catalyzes the formation of 5-O-(1-carboxyvinyl)-3-phosphoshikimate from phosphoenolpyruvate and 3-phosphoshikimate in tryptophan biosynthesis; 3-phosphoshikimate 1-carboxyvinyltransferase complement(1303263..1304555) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112343 YP_002997063.1 CDS SDEG_1354 NC_012891.1 1304653 1305609 R similar to ribonuclease BN [Streptococcus pyogenes MGAS10394]; ribonuclease BN complement(1304653..1305609) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111148 YP_002997064.1 CDS map NC_012891.1 1305611 1306471 R catalyzes the removal of N-terminal amino acids from peptides and arylamides; methionine aminopeptidase complement(1305611..1306471) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111149 YP_002997065.1 CDS SDEG_1356 NC_012891.1 1306488 1307783 R similar to cytosolic protein containing multiple CBS domains [Streptococcus pyogenes MGAS10750]; hypothetical protein complement(1306488..1307783) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110932 YP_002997066.1 CDS SDEG_1357 NC_012891.1 1307764 1308318 R similar to acetyltransferase GNAT family [Streptococcus equi subsp. zooepidemicus MGCS10565]; GNAT family acetyltransferase complement(1307764..1308318) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111150 YP_002997067.1 CDS spg NC_012891.1 1308567 1310138 R similar to immunoglobulin G-binding protein G precursor (IgG-binding protein G); immunoglobulin G-binding protein complement(1308567..1310138) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111151 YP_002997068.1 CDS SDEG_1359 NC_012891.1 1310620 1312416 R similar to glycosyl hydrolase family 3 [Streptococcus agalactiae 515]; glycosyl hydrolase complement(1310620..1312416) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110496 YP_002997069.1 CDS SDEG_1360 NC_012891.1 1312532 1313335 R similar to phosphoglycolate phosphatase [Streptococcus pyogenes MGAS10270]; phosphoglycolate phosphatase complement(1312532..1313335) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111152 YP_002997070.1 CDS SDEG_1361 NC_012891.1 1313604 1314443 R Converts D-mannonate to D-mannuronate; D-mannonate oxidoreductase complement(1313604..1314443) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111153 YP_002997071.1 CDS SDEG_1362 NC_012891.1 1314458 1315558 R catalyzes the formation of 2-dehydro-3-deoxy-D-gluconate from mannonate; mannonate dehydratase complement(1314458..1315558) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111154 YP_002997072.1 CDS SDEG_1363 NC_012891.1 1315647 1316861 R catalyzes the interconversion of D-glucuronate to D-fructuronate or D-galacturonate to D-tagaturonate; functions in glucuronic and galacturonic metabolism; glucuronate isomerase complement(1315647..1316861) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111155 YP_002997073.1 CDS SDEG_1364 NC_012891.1 1316970 1317071 R similar to uronate isomerase [Streptococcus pyogenes MGAS10270]; uronate isomerase complement(1316970..1317071) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111156 YP_002997074.1 CDS SDEG_1365 NC_012891.1 1317074 1317691 R similar to 4-hydroxy-2-oxoglutarate aldolase / 2-dehydro-3-deoxyphosphogluconate aldolase [Streptococcus pyogenes MGAS10270]; 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxyphosphogluconate aldolase complement(1317074..1317691) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111157 YP_002997075.1 CDS SDEG_1366 NC_012891.1 1317819 1318490 R similar to transcriptional regulator GntR family [Streptococcus pyogenes MGAS10270]; GntR family transcriptional regulator complement(1317819..1318490) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111158 YP_002997076.1 CDS SDEG_1367 NC_012891.1 1318532 1320322 R similar to beta-glucuronidase [Streptococcus pyogenes MGAS10270]; beta-D-glucuronidase complement(1318532..1320322) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111159 YP_002997077.1 CDS SDEG_1368 NC_012891.1 1320345 1321373 R similar to 2-dehydro-3-deoxygluconokinase [Streptococcus pyogenes MGAS10270]; 2-dehydro-3-deoxygluconokinase complement(1320345..1321373) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111160 YP_002997078.1 CDS SDEG_1369 NC_012891.1 1321526 1323070 R similar to sugar /sodium symporter [Streptococcus pyogenes MGAS10270]; sugar/sodium symporter complement(1321526..1323070) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111161 YP_002997079.1 CDS murZ NC_012891.1 1323414 1324673 R adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active; UDP-N-acetylglucosamine 1-carboxyvinyltransferase complement(1323414..1324673) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111162 YP_002997080.1 CDS metK2 NC_012891.1 1324862 1326058 R catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase; S-adenosylmethionine synthetase complement(1324862..1326058) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111692 YP_002997081.1 CDS inlA NC_012891.1 1326553 1328919 R similar to internalin protein [Streptococcus pyogenes MGAS10394]; internalin protein complement(1326553..1328919) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110935 YP_002997082.1 CDS birA NC_012891.1 1329095 1330036 D catalyzes the formation of biotinyl-5'-AMP, also acts as a transcriptional repressor of the biotin operon; biotin--protein ligase 1329095..1330036 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112054 YP_002997083.1 CDS SDEG_1374 NC_012891.1 1330011 1330259 R similar to hypothetical protein M28 Spy1103 [Streptococcus pyogenes MGAS6180]; hypothetical protein complement(1330011..1330259) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112377 YP_002997084.1 CDS SDEG_1375 NC_012891.1 1330433 1332112 R catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the tau chain serves as a scaffold to help in the dimerizaton of the alpha,epsilon and theta core complex; the gamma chain seems to interact with the delta and delta' subunits to transfer the beta subunit on the DNA; DNA polymerase III subunits gamma and tau complement(1330433..1332112) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111163 YP_002997085.1 CDS SDEG_1376 NC_012891.1 1332112 1332642 R similar to GAF domain-containing proteins [Streptococcus pyogenes MGAS6180]; GAF domain-containing proteins complement(1332112..1332642) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111164 YP_002997086.1 CDS SDEG_1377 NC_012891.1 1332749 1333564 D similar to hypothetical protein SPy 1366 [Streptococcus pyogenes M1 GAS]; hypothetical protein 1332749..1333564 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111165 YP_002997087.1 CDS SDEG_1378 NC_012891.1 1333609 1333881 R similar to hypothetical membrane spanning protein [Streptococcus pyogenes MGAS10394]; hypothetical protein complement(1333609..1333881) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111166 YP_002997088.1 CDS udk NC_012891.1 1333942 1334580 R functions in pyrimidine salvage; pyrimidine ribonucleoside kinase; phosphorylates nucleosides or dinucleosides to make UMP or CMP using ATP or GTP as the donor; uridine kinase complement(1333942..1334580) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111167 YP_002997089.1 CDS deaD NC_012891.1 1334633 1335751 D similar to ATP-dependent RNA helicase [Streptococcus pyogenes MGAS10394]; ATP-dependent RNA helicase 1334633..1335751 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111938 YP_002997090.1 CDS SDEG_1381 NC_012891.1 1336019 1336546 D similar to transposase [Streptococcus pyogenes MGAS10750]; transposase 1336019..1336546 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111664 YP_002997091.1 CDS SDEG_1382 NC_012891.1 1336615 1337130 D similar to transposase [Streptococcus pyogenes MGAS5005]; transposase 1336615..1337130 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111168 YP_002997092.1 CDS SDEG_1383 NC_012891.1 1337155 1337373 D similar to transposase [Streptococcus pyogenes MGAS5005]; transposase 1337155..1337373 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111169 YP_002997093.1 CDS SDEG_1384 NC_012891.1 1337433 1338275 R similar to haloacid dehalogenase-like hydrolase [Streptococcus suis 89/1591]; haloacid dehalogenase-like hydrolase complement(1337433..1338275) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111170 YP_002997094.1 CDS SDEG_1385 NC_012891.1 1338363 1339067 R similar to hypothetical protein CLOBAR 01981 [Clostridium bartlettii DSM 16795]; hypothetical protein complement(1338363..1339067) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111171 YP_002997095.1 CDS arb NC_012891.1 1339240 1340709 R required for arbutin uptake and metabolism; 6-phospho-beta-glucosidase complement(1339240..1340709) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111172 YP_002997096.1 CDS SDEG_1387 NC_012891.1 1340788 1341390 R similar to phosphoglycerate mutase family protein [Streptococcus sanguinis SK36]; phosphoglycerate mutase complement(1340788..1341390) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111173 YP_002997097.1 CDS SDEG_1388 NC_012891.1 1341408 1342019 R similar to hypothetical protein STRINF 01174 [Streptococcus infantarius subsp. infantarius ATCC BAA-102]; hypothetical protein complement(1341408..1342019) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111174 YP_002997098.1 CDS SDEG_1389 NC_012891.1 1342029 1342634 R phosphoglycerate mutase complement(1342029..1342634) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111175 YP_002997099.1 CDS SDEG_1390 NC_012891.1 1342768 1343244 R similar to hypothetical protein lwe2314 [Listeria welshimeri serovar 6b str. SLCC5334]; hypothetical protein complement(1342768..1343244) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111176 YP_002997100.1 CDS SDEG_1391 NC_012891.1 1343296 1343574 R similar to hypothetical protein STRINF 01173 [Streptococcus infantarius subsp. infantarius ATCC BAA-102]; hypothetical protein complement(1343296..1343574) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111177 YP_002997101.1 CDS SDEG_1392 NC_012891.1 1343630 1344376 R probable ORF of C-terminal portion of glycoside hydrolase, family 1 [Streptococcus suis 89/1591] resulted from mutation by unknown reason; glycoside hydrolase family 1 complement(1343630..1344376) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111178 YP_002997102.1 CDS SDEG_1393 NC_012891.1 1344373 1344768 R probable ORF of N-terminal portion of glycoside hydrolase, family 1 [Streptococcus suis 89/1591] resulted from mutation by unknown reason; glycoside hydrolase family 1 complement(1344373..1344768) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111179 YP_002997103.1 CDS SDEG_1394 NC_012891.1 1344870 1345421 R similar to acetyltransferase [Clostridium difficile ATCC 43255]; acetyltransferase complement(1344870..1345421) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111180 YP_002997104.1 CDS SDEG_1395 NC_012891.1 1345405 1346253 R similar to haloacid dehalogenase-like hydrolase [Streptococcus gordonii str. Challis substr. CH1]; haloacid dehalogenase-like hydrolase complement(1345405..1346253) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111181 YP_002997105.1 CDS SDEG_1396 NC_012891.1 1346341 1347438 R similar to hypothetical protein PEPE 0230 [Pediococcus pentosaceus ATCC 25745]; hypothetical protein complement(1346341..1347438) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111182 YP_002997106.1 CDS celD NC_012891.1 1347508 1348860 R required for cellobiose uptake and metabolism; cellobiose phosphotransferase system IIC component complement(1347508..1348860) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111183 YP_002997107.1 CDS SDEG_1398 NC_012891.1 1348894 1349400 R similar to conserved hypothetical protein [Bacillus coagulans 36D1]; hypothetical protein complement(1348894..1349400) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111184 YP_002997108.1 CDS celC NC_012891.1 1349419 1349739 R required for cellobiose uptake and metabolism; cellobiose phosphotransferase system IIA component complement(1349419..1349739) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111185 YP_002997109.1 CDS bglG NC_012891.1 1349739 1351724 R similar to transcriptional antiterminator bglG [Streptococcus suis 89/1591]; transcriptional antiterminator bglG complement(1349739..1351724) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111186 YP_002997110.1 CDS celB NC_012891.1 1351768 1352097 R required for cellobiose uptake and metabolism; PTS system cellobiose transporter subunit IIB complement(1351768..1352097) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112374 YP_002997111.1 CDS SDEG_1402 NC_012891.1 1352618 1353397 R similar to ISSdy1, transposase OrfB [Streptococcus agalactiae 2603V/R]; ISSdy1, transposase OrfB complement(1352618..1353397) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111187 YP_002997112.1 CDS SDEG_1403 NC_012891.1 1353433 1353723 R similar to ISSag4, transposase orfA [Streptococcus agalactiae A909]; ISSag4, transposase orfA complement(1353433..1353723) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111188 YP_002997113.1 CDS SDEG_1404 NC_012891.1 1354158 1354460 R similar to hypothetical protein SsuiDRAFT 1295 [Streptococcus suis 89/1591]; hypothetical protein complement(1354158..1354460) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111189 YP_002997114.1 CDS tnp1191 NC_012891.1 1354684 1355892 R similar to IS1191 transposase [Streptococcus thermophilus LMG 18311]; IS1191 transposase complement(1354684..1355892) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111190 YP_002997115.1 CDS SDEG_1406 NC_012891.1 1356132 1356371 R similar to conserved hypothetical protein [Streptococcus suis 89/1591]; hypothetical protein complement(1356132..1356371) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110527 YP_002997116.1 CDS celA NC_012891.1 1356388 1357827 R converts 6-phospho-beta-D-glucosyl-(1,4)-D-glucose to glucose and glucose 6-phosphate; required for cellobiose uptake and metabolism; 6-phospho-beta-glucosidase complement(1356388..1357827) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111191 YP_002997117.1 CDS SDEG_1408 NC_012891.1 1357929 1358861 R similar to protein of unknown function/lipoprotein [Streptococcus agalactiae 2603V/R]; lipoprotein complement(1357929..1358861) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112371 YP_002997118.1 CDS SDEG_1409 NC_012891.1 1359055 1359477 D similar to phosphosugar-binding transcriptional regulator [Clostridium botulinum NCTC2916]; phosphosugar-binding transcriptionalregulator 1359055..1359477 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111192 YP_002997119.1 CDS SDEG_1410 NC_012891.1 1359705 1360319 R similar to hypothetical protein SMU.1108c [Streptococcus mutans UA159]; hypothetical protein complement(1359705..1360319) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111193 YP_002997120.1 CDS SDEG_1411 NC_012891.1 1360330 1361052 R similar to oxidoreductase [Lactobacillus plantarum WCFS1]; oxidoreductase complement(1360330..1361052) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111194 YP_002997121.1 CDS bglA NC_012891.1 1361628 1363073 R similar to beta-glucosidase, [Streptococcus sanguinis SK36]; beta-glucosidas complement(1361628..1363073) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111195 YP_002997122.1 CDS SDEG_1413 NC_012891.1 1363219 1364148 D similar to hypothetical protein STRINF 01402 [Streptococcus infantarius subsp. infantarius ATCC BAA-102]; hypothetical protein 1363219..1364148 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112373 YP_002997123.1 CDS SDEG_1414 NC_012891.1 1364223 1366136 R PTS system beta-glucoside-specific IIABC component [Streptococcus suis 89/1591]; similar to sugar-specific permease EIIA 1 domain; PTS system beta-glucoside-specific transporter subunit IIABC complement(1364223..1366136) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111196 YP_002997124.1 CDS SDEG_1415 NC_012891.1 1366375 1367241 R similar to hypothetical protein STRINF 01404 [Streptococcus infantarius subsp. infantarius ATCC BAA-102]; hypothetical protein complement(1366375..1367241) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111197 YP_002997125.1 CDS SDEG_1416 NC_012891.1 1367357 1368097 R similar to permease ATP-binding protein [Streptococcus gordonii str. Challis substr. CH1]; permease ATP-binding protein complement(1367357..1368097) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111198 YP_002997126.1 CDS SDEG_1417 NC_012891.1 1368408 1368833 D similar to transposase IS861 orfB [Streptococcus equi subsp. zooepidemicus MGCS10565]; transposase IS861 orfB 1368408..1368833 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111199 YP_002997127.1 CDS SDEG_1418 NC_012891.1 1368923 1370209 R similar to polysaccharide deacetylase family protein [Streptococcus pyogenes NZ131]; polysaccharide deacetylase complement(1368923..1370209) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111200 YP_002997128.1 CDS gapN NC_012891.1 1370295 1371722 R similar to NADP-dependent glyceraldehyde-3-phosphate dehydrogenase [Streptococcus pyogenes MGAS5005]; NADP-dependent glyceraldehyde-3-phosphatedehydrogenase complement(1370295..1371722) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111201 YP_002997129.1 CDS pstI NC_012891.1 1371889 1373622 R similar to phosphoenolpyruvate-protein phosphotransferase [Streptococcus pyogenes MGAS5005]; phosphoenolpyruvate-protein phosphotransferase complement(1371889..1373622) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111985 YP_002997130.1 CDS ptsH NC_012891.1 1373627 1373890 R similar to phosphocarrier protein HPr [Streptococcus pyogenes MGAS10394]; phosphocarrier protein HPr complement(1373627..1373890) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111319 YP_002997131.1 CDS SDEG_1422 NC_012891.1 1374275 1374493 D similar to glutaredoxin [Streptococcus pyogenes MGAS10394]; glutaredoxin 1374275..1374493 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111326 YP_002997132.1 CDS nrdE.2 NC_012891.1 1374513 1376672 D Catalyzes the rate-limiting step in dNTP synthesis; ribonucleotide-diphosphate reductase subunit alpha 1374513..1376672 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111202 YP_002997133.1 CDS nrdF NC_012891.1 1377005 1377964 D B2 or R2 protein; type 1b enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdE; ribonucleotide-diphosphate reductase subunit beta 1377005..1377964 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111716 YP_002997134.1 CDS SDEG_1425 NC_012891.1 1377942 1379300 D similar to chloride channel protein [Streptococcus pyogenes MGAS10270]; chloride channel protein 1377942..1379300 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111718 YP_002997135.1 CDS SDEG_1426 NC_012891.1 1379335 1380030 R similar to CAAX amino terminal protease family [Streptococcus pyogenes MGAS5005]; CAAX amino terminal protease complement(1379335..1380030) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111203 YP_002997136.1 CDS SDEG_1427 NC_012891.1 1380049 1380810 R similar to hypothetical membrane spanning protein [Streptococcus pyogenes MGAS10394]; hypothetical protein complement(1380049..1380810) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111204 YP_002997137.1 CDS SDEG_1428 NC_012891.1 1380807 1381022 R similar to transcriptional regulator Cro /CI family [Streptococcus pyogenes MGAS10394]; Cro/CI family transcriptional regulator complement(1380807..1381022) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111205 YP_002997138.1 CDS SDEG_1429 NC_012891.1 1381022 1381576 R similar to probable surface antigen negative regulator Par [Streptococcus suis 98HAH33]; surface antigen negative regulator complement(1381022..1381576) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111206 YP_002997139.1 CDS alaS NC_012891.1 1381736 1384354 R Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; alanyl-tRNA synthetase complement(1381736..1384354) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111207 YP_002997140.1 CDS SDEG_1431 NC_012891.1 1384370 1384855 R similar to hypothetical protein SAK 0933 [Streptococcus agalactiae A909]; hypothetical protein complement(1384370..1384855) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112319 YP_002997141.1 CDS prsA NC_012891.1 1385110 1386177 R cis/trans isomerase of peptidylprolyl; PPIase; membrane-bound lipoprotein; foldase protein PrsA complement(1385110..1386177) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111208 YP_002997142.1 CDS SDEG_1433 NC_012891.1 1386240 1386947 R similar to methyltransferase [Streptococcus pyogenes SSI-1]; methyltransferase complement(1386240..1386947) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111314 YP_002997143.1 CDS SDEG_1434 NC_012891.1 1386999 1388210 R similar to oxalate formate antiporter [Streptococcus pyogenes SSI-1]; oxalate/formate antiporter complement(1386999..1388210) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111209 YP_002997144.1 CDS SDEG_1435 NC_012891.1 1388544 1389167 R similar to hydrolase haloacid dehalogenase-like family [Streptococcus equi subsp. zooepidemicus MGCS10565]; haloacid dehalogenase family hydrolase complement(1388544..1389167) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111210 YP_002997145.1 CDS SDEG_1436 NC_012891.1 1389167 1389709 R similar to acetyltransferase GNAT family [Streptococcus equi subsp. zooepidemicus MGCS10565]; GNAT family acetyltransferase complement(1389167..1389709) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111211 YP_002997146.1 CDS SDEG_1437 NC_012891.1 1389839 1390393 R similar to NADPH-dependent FMN reductase [Bacillus coagulans 36D1]; NADPH-dependent FMN reductase complement(1389839..1390393) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111212 YP_002997147.1 CDS pepB NC_012891.1 1390574 1392376 R similar to oligoendopeptidase F [Streptococcus pyogenes MGAS5005]; oligoendopeptidase F complement(1390574..1392376) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111213 YP_002997148.1 CDS SDEG_1439 NC_012891.1 1392387 1393346 R similar to competence protein/transcription factor [Streptococcus pyogenes MGAS10394]; competence protein/transcriptionfactor complement(1392387..1393346) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111273 YP_002997149.1 CDS SDEG_1440 NC_012891.1 1393461 1394378 R probable ORF of C-terminal portion of major facilitator family protein [Streptococcus agalactiae 2603V/R] resulted from mutation by unknown reason; major facilitator family protein complement(1393461..1394378) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111214 YP_002997150.1 CDS SDEG_1441 NC_012891.1 1394369 1394620 R probable ORF of N-terminal portion of major facilitator family protein [Streptococcus agalactiae 2603V/R] resulted from mutation by unknown reason; major facilitator family protein complement(1394369..1394620) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111215 YP_002997151.1 CDS SDEG_1442 NC_012891.1 1394712 1395428 R similar to 16S pseudouridylate synthetase [Streptococcus pyogenes MGAS8232]; 16S pseudouridylate synthetase complement(1394712..1395428) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111216 YP_002997152.1 CDS nagB NC_012891.1 1395532 1396245 R similar to glucosamine-6-phosphate isomerase [Streptococcus pyogenes MGAS10394]; glucosamine-6-phosphate isomerase complement(1395532..1396245) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111217 YP_002997153.1 CDS queA NC_012891.1 1396443 1397471 D Synthesizes oQ from preQ1 in a single S-adenosylmethionine-requiring step; S-adenosylmethionine--tRNA ribosyltransferase-isomerase 1396443..1397471 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111707 YP_002997154.1 CDS SDEG_1445 NC_012891.1 1397476 1398696 D similar to hypothetical cytosolic protein [Streptococcus pyogenes MGAS10750]; hypothetical protein 1397476..1398696 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111347 YP_002997155.1 CDS SDEG_1446 NC_012891.1 1398817 1399878 R similar to hypothetical protein SSA 0722 [Streptococcus sanguinis SK36]; hypothetical protein complement(1398817..1399878) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111218 YP_002997156.1 CDS sodA NC_012891.1 1400045 1400650 R similar to superoxide dismutase [Streptococcus pyogenes MGAS6180]; superoxide dismutase complement(1400045..1400650) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111219 YP_002997157.1 CDS holA NC_012891.1 1400747 1401787 R required for the assembly and function of the DNAX complex which is required for the assembly of the beta subunit onto primed DNA; DNA polymerase III subunit delta complement(1400747..1401787) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110494 YP_002997158.1 CDS comEC NC_012891.1 1401868 1404111 R similar to competence protein [Streptococcus pyogenes str. Manfredo]; competence protein complement(1401868..1404111) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112034 YP_002997159.1 CDS comEA NC_012891.1 1404092 1404754 R similar to competence protein [Streptococcus pyogenes str. Manfredo]; competence protein complement(1404092..1404754) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111634 YP_002997160.1 CDS SDEG_1451 NC_012891.1 1405151 1405969 R similar to 1-acyl-sn-glycerol-3-phosphate acyltransferase [Streptococcus pyogenes MGAS10270]; 1-acyl-sn-glycerol-3-phosphate acyltransferase complement(1405151..1405969) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111632 YP_002997161.1 CDS SDEG_1452 NC_012891.1 1405931 1406785 D similar to methyltransferase [Streptococcus pyogenes MGAS6180]; methyltransferase 1405931..1406785 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111220 YP_002997162.1 CDS SDEG_1453 NC_012891.1 1406775 1407053 D similar to hypothetical protein with endo/excinuclease domain [Streptococcus pyogenes MGAS10394]; hypothetical protein 1406775..1407053 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111221 YP_002997163.1 CDS SDEG_1454 NC_012891.1 1407077 1409077 R similar to Kup system potassium uptake protein [Streptococcus pyogenes MGAS10394]; Kup system potassium uptake protein complement(1407077..1409077) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111222 YP_002997164.1 CDS deaD NC_012891.1 1409205 1410824 R similar to ATP-dependent RNA helicase [Streptococcus pyogenes MGAS5005]; ATP-dependent RNA helicase complement(1409205..1410824) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111223 YP_002997165.1 CDS SDEG_1456 NC_012891.1 1411053 1411883 R similar to YaeC family protein [Streptococcus agalactiae 2603V/R]; YaeC family protein complement(1411053..1411883) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111665 YP_002997166.1 CDS SDEG_1457 NC_012891.1 1411907 1412569 R similar to ABC transporter permease protein [Streptococcus agalactiae 2603V /R]; ABC transporter permease complement(1411907..1412569) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111224 YP_002997167.1 CDS SDEG_1458 NC_012891.1 1412562 1413296 R similar to ABC transporter ATP-binding protein [Streptococcus agalactiae 2603V/R]; ABC transporter ATP-binding protein complement(1412562..1413296) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111225 YP_002997168.1 CDS SDEG_1459 NC_012891.1 1413504 1413887 R similar to superfamily I DNA and RNA helicase [Streptococcus suis 98HAH33]; superfamily I DNA and RNA helicase complement(1413504..1413887) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111226 YP_002997169.1 CDS prfC NC_012891.1 1414015 1415559 R stimulates the release of release factors 1 and 2 from the ribosome after hydrolysis of the ester bond in peptidyl-tRNA has occurred; GDP/GTP-binding protein; peptide chain release factor 3 complement(1414015..1415559) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111227 YP_002997170.1 CDS SDEG_1461 NC_012891.1 1415807 1416508 R similar to hypothetical membrane spanning protein [Streptococcus pyogenes MGAS5005]; hypothetical protein complement(1415807..1416508) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111307 YP_002997171.1 CDS murF NC_012891.1 1416606 1417973 R similar to D-Ala-D-Ala adding enzyme [Streptococcus pyogenes MGAS315]; D-Ala-D-Ala adding enzyme complement(1416606..1417973) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111228 YP_002997172.1 CDS ddl NC_012891.1 1418179 1419225 R similar to D-alanylalanine synthetase [Streptococcus pyogenes M1 GAS]; D-alanyl-alanine synthetase A complement(1418179..1419225) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111687 YP_002997173.1 CDS recR NC_012891.1 1419397 1419993 R involved in a recombinational process of DNA repair, independent of the recBC complex; recombination protein RecR complement(1419397..1419993) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111663 YP_002997174.1 CDS ftsI NC_012891.1 1420005 1422059 R similar to cell division protein FtsI [Streptococcus equi subsp. zooepidemicus MGCS10565]; cell division protein complement(1420005..1422059) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111038 YP_002997175.1 CDS SDEG_1466 NC_012891.1 1422166 1422963 R similar to formate transporter [Streptococcus pyogenes MGAS10270]; formate transporter complement(1422166..1422963) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111917 YP_002997176.1 CDS SDEG_1467 NC_012891.1 1423063 1423605 R similar to hypothetical protein SPy 1425 [Streptococcus pyogenes M1 GAS]; hypothetical protein complement(1423063..1423605) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111229 YP_002997177.1 CDS SDEG_1468 NC_012891.1 1423707 1424228 R similar to transcriptional regulator [Streptococcus pyogenes M1 GAS]; transcriptional regulator complement(1423707..1424228) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111230 YP_002997178.1 CDS gpmA NC_012891.1 1424338 1425033 R 2,3-bisphosphoglycerate-dependent; catalyzes the interconversion of 2-phosphoglycerate to 3-phosphoglycerate; phosphoglyceromutase complement(1424338..1425033) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111231 YP_002997179.1 CDS SDEG_1470 NC_012891.1 1425243 1426271 R similar to transposase [Streptococcus pyogenes MGAS10270]; transposase complement(1425243..1426271) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111232 YP_002997180.1 CDS pyrD NC_012891.1 1426437 1427384 D catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway; subclass 1A is a dimer formed by two identical PyrD subunits each containing an FMN group; dihydroorotate dehydrogenase 1A 1426437..1427384 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111233 YP_002997181.1 CDS SDEG_1472 NC_012891.1 1427442 1427615 R similar to hypothetical protein M6 Spy1192 [Streptococcus pyogenes MGAS10394]; hypothetical protein complement(1427442..1427615) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111340 YP_002997182.1 CDS SDEG_1473 NC_012891.1 1427687 1429549 R similar to heavy metal-transporting ATPase [Streptococcus pyogenes M1 GAS]; heavy metal-transporting ATPase complement(1427687..1429549) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111234 YP_002997183.1 CDS SDEG_1474 NC_012891.1 1429753 1430625 D similar to positive transcriptional regulator MutR family [Streptococcus equi subsp. zooepidemicus MGCS10565]; positive transcriptional regulator MutR family 1429753..1430625 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111235 YP_002997184.1 CDS SDEG_1475 NC_012891.1 1430695 1431885 D similar to transporter probable SP1116 [Streptococcus gordonii str. Challis substr. CH1]; transporter 1430695..1431885 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111236 YP_002997185.1 CDS SDEG_1476 NC_012891.1 1432081 1432356 R similar to DNA-binding protein HU [Streptococcus pyogenes MGAS10394]; DNA-binding protein HU complement(1432081..1432356) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111237 YP_002997186.1 CDS SDEG_1477 NC_012891.1 1432455 1433042 R similar to hypothetical protein SPy 1491 [Streptococcus pyogenes M1 GAS]; hypothetical protein complement(1432455..1433042) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111238 YP_002997187.1 CDS SDEG_1478 NC_012891.1 1433020 1433892 R similar to Lipase /Acylhydrolase with GDSL-like motif [Streptococcus pyogenes MGAS10750]; lipase/acylhydrolase with GDSL-like motif complement(1433020..1433892) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111239 YP_002997188.1 CDS SDEG_1479 NC_012891.1 1433855 1434706 R similar to DegV family protein [Streptococcus pyogenes MGAS10394]; DegV family fatty acid binding protein complement(1433855..1434706) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111240 YP_002997189.1 CDS SDEG_1480 NC_012891.1 1434935 1435831 R similar to hypothetical protein M28 Spy1166 [Streptococcus pyogenes MGAS6180]; hypothetical protein complement(1434935..1435831) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111241 YP_002997190.1 CDS recN NC_012891.1 1436038 1437702 R similar to RecN [Streptococcus pyogenes MGAS10394]; DNA repair protein complement(1436038..1437702) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111242 YP_002997191.1 CDS argR1 NC_012891.1 1437718 1438221 R similar to arginine repressor argR [Streptococcus pyogenes MGAS10750]; arginine repressor complement(1437718..1438221) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111036 YP_002997192.1 CDS SDEG_1483 NC_012891.1 1438175 1439002 R similar to hemolysin [Streptococcus pyogenes MGAS5005]; hemolysin complement(1438175..1439002) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112335 YP_002997193.1 CDS fps NC_012891.1 1438995 1439867 R similar to dimethylallyltransferase/ geranyltranstransferase [Streptococcus pyogenes MGAS5005]; trans-Isoprenyl Diphosphate Synthases (trans IPPS)head-to-tail (HT) (1'-4) condensation reactions; cd00685; dimethylallyltransferase/ geranyltranstransferase complement(1438995..1439867) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111243 YP_002997194.1 CDS xseB NC_012891.1 1439867 1440082 R catalyzes the bidirectional exonucleolytic cleavage of DNA; exodeoxyribonuclease VII small subunit complement(1439867..1440082) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111908 YP_002997195.1 CDS xseA NC_012891.1 1440060 1441400 R bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides; exodeoxyribonuclease VII large subunit complement(1440060..1441400) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111955 YP_002997196.1 CDS SDEG_1487 NC_012891.1 1441551 1442396 R similar to sugar kinase [Streptococcus equi subsp. zooepidemicus MGCS10565]; sugar kinase complement(1441551..1442396) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111954 YP_002997197.1 CDS SDEG_1488 NC_012891.1 1442393 1443247 R catalyzes the formation of 5,10-methenyltetrahydrofolate from 5,10-methylenetetrahydrofolate and subsequent formation of 10-formyltetrahydrofolate from 5,10-methenyltetrahydrofolate; bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase complement(1442393..1443247) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111244 YP_002997198.1 CDS SDEG_1489 NC_012891.1 1443420 1445114 R similar to phosphoglucomutase [Streptococcus pyogenes MGAS5005]; phosphoglucomutase complement(1443420..1445114) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111245 YP_002997199.1 CDS phr NC_012891.1 1445267 1446691 R similar to deoxyribodipyrimidine photolyase [Streptococcus pyogenes MGAS5005]; deoxyribodipyrimidine photolyase complement(1445267..1446691) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111246 YP_002997200.1 CDS SDEG_1491 NC_012891.1 1446884 1447033 R similar to hypothetical protein SMU.571 [Streptococcus mutans UA159]; hypothetical protein complement(1446884..1447033) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111295 YP_002997201.1 CDS feoB NC_012891.1 1447033 1449192 R similar to ferrous ion transport protein B [Streptococcus mutans UA159]; ferrous ion transport protein B complement(1447033..1449192) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111247 YP_002997202.1 CDS feoA NC_012891.1 1449189 1449668 R similar to ferrous ion transport protein A [Streptococcus mutans UA159]; ferrous ion transport protein A complement(1449189..1449668) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111888 YP_002997203.1 CDS artP NC_012891.1 1449866 1450600 R similar to amino acid transport ATP-binding protein [Streptococcus pyogenes MGAS10394]; amino acid transport ATP-binding protein complement(1449866..1450600) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111887 YP_002997204.1 CDS artQ NC_012891.1 1450600 1451286 R similar to arginine transport system permease protein [Streptococcus pyogenes MGAS5005]; arginine transport system permease complement(1450600..1451286) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112345 YP_002997205.1 CDS clpE NC_012891.1 1451942 1454233 D similar to ATP-dependent endopeptidase clp ATP-binding subunit clpE [Streptococcus pyogenes MGAS2096]; ATP-dependent endopeptidase clp ATP-binding subunit 1451942..1454233 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112346 YP_002997206.1 CDS mutT NC_012891.1 1454351 1454806 D 7,8-dihydro-8-oxoguanine-triphosphatase; similar to mutator protein (78-dihydro-8-oxoguanine-triphosphatase) [Streptococcus pyogenes MGAS6180]; mutator protein 1454351..1454806 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111622 YP_002997207.1 CDS SDEG_1498 NC_012891.1 1454856 1455158 D similar to hypothetical cytosolic protein [Streptococcus pyogenes MGAS10394]; hypothetical protein 1454856..1455158 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111697 YP_002997208.1 CDS ileS NC_012891.1 1455560 1458361 R IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase family; some organisms carry two different copies of this enzyme; isoleucyl-tRNA synthetase complement(1455560..1458361) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111248 YP_002997209.1 CDS divIVAS NC_012891.1 1458627 1459382 R similar to cell division initiation protein DivIVA [Streptococcus pyogenes MGAS6180]; cell division initiation protein DivIVA complement(1458627..1459382) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112050 YP_002997210.1 CDS SDEG_1501 NC_012891.1 1459392 1460183 R similar to hypothetical protein SpyM50607 [Streptococcus pyogenes str. Manfredo]; hypothetical protein complement(1459392..1460183) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111675 YP_002997211.1 CDS SDEG_1502 NC_012891.1 1460183 1460437 R similar to hypothetical protein SpyM50606 [Streptococcus pyogenes str. Manfredo]; hypothetical protein complement(1460183..1460437) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111249 YP_002997212.1 CDS SDEG_1503 NC_012891.1 1460443 1461114 R similar to hypothetical cytosolic protein [Streptococcus pyogenes MGAS10750]; hypothetical protein complement(1460443..1461114) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111250 YP_002997213.1 CDS SDEG_1504 NC_012891.1 1461115 1461786 R similar to pyridoxaL 5'-phosphate dependent enzyme class III family [Streptococcus equi subsp. zooepidemicus MGCS10565]; pyridoxaL 5'-phosphate dependent enzyme classIII family complement(1461115..1461786) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111251 YP_002997214.1 CDS ftsZ NC_012891.1 1461789 1463108 R GTPase; similar structure to tubulin; forms ring-shaped polymers at the site of cell division; other proteins such as FtsA, ZipA, and ZapA, interact with and regulate FtsZ function; cell division protein FtsZ complement(1461789..1463108) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111252 YP_002997215.1 CDS ftsA NC_012891.1 1463132 1464496 R similar to cell division protein [Streptococcus pyogenes MGAS5005]; cell division protein complement(1463132..1464496) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111979 YP_002997216.1 CDS ftsQ NC_012891.1 1464707 1465675 R probable ORF of C-terminal portion of cell division protein [Streptococcus pyogenes MGAS8232] resulted from mutation by unknown reason; cell division protein complement(1464707..1465675) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111914 YP_002997217.1 CDS ftsQ NC_012891.1 1465488 1465856 R probable ORF of N-terminal portion of cell division protein [Streptococcus pyogenes MGAS8232] resulted from mutation by unknown reason; cell division protein complement(1465488..1465856) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111974 YP_002997218.1 CDS murG NC_012891.1 1465857 1466939 R UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; involved in cell wall formation; inner membrane-associated; last step of peptidoglycan synthesis; UDP diphospho-muramoyl pentapeptide beta-N acetylglucosaminyl transferase complement(1465857..1466939) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111975 YP_002997219.1 CDS murD NC_012891.1 1466939 1468309 R UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase complement(1466939..1468309) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111688 YP_002997220.1 CDS SDEG_1511 NC_012891.1 1468544 1470181 R similar to hypothetical protein [Streptococcus suis]; hypothetical protein complement(1468544..1470181) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111685 YP_002997221.1 CDS SDEG_1512 NC_012891.1 1470434 1470691 R similar to hypothetical protein Sez 0590 [Streptococcus equi subsp. zooepidemicus MGCS10565]; hypothetical protein complement(1470434..1470691) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111253 YP_002997222.1 CDS typA NC_012891.1 1470790 1472631 R similar to GTP-binding protein [Streptococcus pyogenes MGAS5005]; GTP-binding protein complement(1470790..1472631) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111254 YP_002997223.1 CDS SDEG_1514 NC_012891.1 1472813 1473202 R similar to rhodanese-related sulfurtransferase [Streptococcus pyogenes MGAS5005]; rhodanese-related sulfurtransferase complement(1472813..1473202) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111936 YP_002997224.1 CDS glcK NC_012891.1 1473212 1474183 R similar to glucokinase/xylose repressor [Streptococcus pyogenes MGAS5005]; glucokinase/xylose repressor complement(1473212..1474183) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111255 YP_002997225.1 CDS SDEG_1516 NC_012891.1 1474188 1474409 R similar to hypothetical cytosolic protein [Streptococcus pyogenes MGAS10394]; hypothetical protein complement(1474188..1474409) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111994 YP_002997226.1 CDS SDEG_1517 NC_012891.1 1474533 1475060 R similar to ferroxidase [Streptococcus pyogenes MGAS10394]; ferroxidase complement(1474533..1475060) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111256 YP_002997227.1 CDS SDEG_1518 NC_012891.1 1475279 1475914 D similar to prepilin peptidase family [Streptococcus pyogenes MGAS6180]; prepilin peptidase family 1475279..1475914 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111257 YP_002997228.1 CDS SDEG_1519 NC_012891.1 1475957 1476553 R similar to TCS response regulator [Streptococcus equi subsp. zooepidemicus MGCS10565]; two-component system response regulator complement(1475957..1476553) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111258 YP_002997229.1 CDS SDEG_1520 NC_012891.1 1476534 1477640 R similar to TCS sensor histidine kinase [Streptococcus equi subsp. zooepidemicus MGCS10565]; two-component system sensor histidine kinase complement(1476534..1477640) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111259 YP_002997230.1 CDS SDEG_1521 NC_012891.1 1477640 1478365 R similar to ABC transporter permease protein [Streptococcus equi subsp. zooepidemicus MGCS10565]; ABC transporter permease complement(1477640..1478365) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111260 YP_002997231.1 CDS SDEG_1522 NC_012891.1 1478369 1479256 R similar to multi drug transpot ATP-binding protein [Streptococcus equi subsp.; multi drug transpot ATP-binding protein complement(1478369..1479256) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111261 YP_002997232.1 CDS SDEG_1523 NC_012891.1 1479395 1481131 R similar to hypothetical protein gbs0508 [Streptococcus agalactiae NEM316]; hypothetical protein complement(1479395..1481131) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111262 YP_002997233.1 CDS SDEG_1524 NC_012891.1 1481118 1481504 R similar to ABC transporter ATP-binding/permease protein [Streptococcus pneumoniae D39]; ABC transporter ATP-binding protein/permease complement(1481118..1481504) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111263 YP_002997234.1 CDS SDEG_1525 NC_012891.1 1481569 1482864 R similar to ABC transporter ATP-binding/permease protein [Streptococcus agalactiae A909]; ABC transporter ATP-binding protein/permease complement(1481569..1482864) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111264 YP_002997235.1 CDS SDEG_1526 NC_012891.1 1482959 1483474 R similar to VanZF domain protein [Streptococcus agalactiae COH1]; VanZF domain-containing protein complement(1482959..1483474) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111265 YP_002997236.1 CDS SDEG_1527 NC_012891.1 1483479 1484561 R 23S rRNA m2A2503 methyltransferase; methylates the C2 position of the A2530 nucleotide in 23S rRNA; may be involved in antibiotic resistance; ribosomal RNA large subunit methyltransferase N complement(1483479..1484561) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111266 YP_002997237.1 CDS SDEG_1528 NC_012891.1 1484565 1485179 R similar to transcriptional regulator [Streptococcus pyogenes MGAS5005]; transcriptional regulator complement(1484565..1485179) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111267 YP_002997238.1 CDS SDEG_1529 NC_012891.1 1485438 1485845 R probable ORF of C-terminal portion of hypothetical protein SMU.796 [Streptococcus mutans UA159] resulted from mutation by unknown reason; hypothetical protein complement(1485438..1485845) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111268 YP_002997239.1 CDS SDEG_1530 NC_012891.1 1485860 1486189 R probable ORF of N-terminal portion of hypothetical protein SMU.796 [Streptococcus mutans UA159] resulted from mutation by unknown reason; hypothetical protein complement(1485860..1486189) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111269 YP_002997240.1 CDS SDEG_1531 NC_012891.1 1486583 1487230 D similar to hypothetical protein CLONEX 04238 [Clostridium nexile DSM 1787]; hypothetical protein 1486583..1487230 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111270 YP_002997241.1 CDS SDEG_1532 NC_012891.1 1487295 1487726 D similar to transposase [Streptococcus pneumoniae SP9-BS68]; transposase 1487295..1487726 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111271 YP_002997242.1 CDS rbsB NC_012891.1 1488036 1488815 R similar to D-ribose-binding protein precursor RbsB [Streptococcus equi subsp.; D-ribose-binding protein complement(1488036..1488815) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111272 YP_002997243.1 CDS rbsA NC_012891.1 1488812 1489195 R similar to ribose transport ATP-binding protein RbsA [Streptococcus equi subsp. zooepidemicus MGCS10565]; ribose transport ATP-binding protein complement(1488812..1489195) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111352 YP_002997244.1 CDS rbsD NC_012891.1 1489211 1489609 R cytoplasmic mutarotase that catalyzes the conversion between beta-pyran and beta-furan forms of D-ribose; RbsD is required for efficient ribose utilization in E. coli; rbsD-mutant E. coli strains are unable to use ribose as a sole carbon source; D-ribose pyranase complement(1489211..1489609) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111351 YP_002997245.1 CDS rbsK NC_012891.1 1489584 1490495 R similar to ribokinase RbsK [Streptococcus equi subsp. zooepidemicus MGCS10565]; ribokinase complement(1489584..1490495) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111353 YP_002997246.1 CDS SDEG_1537 NC_012891.1 1490488 1491471 R similar to ribose transport operon repressor [Streptococcus pyogenes MGAS315]; ribose transport operon repressor complement(1490488..1491471) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111030 YP_002997247.1 CDS SDEG_1538 NC_012891.1 1491752 1492789 R similar to ATP-dependent endopeptidase Lon [Streptococcus pyogenes MGAS10270]; ATP-dependent endopeptidase complement(1491752..1492789) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112136 YP_002997248.1 CDS coaD NC_012891.1 1492776 1493267 R Catalyzes the conversion of ATP and pantetheine 4'-phosphate to diphosphate and 3'-dephospho-coA; phosphopantetheine adenylyltransferase complement(1492776..1493267) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112137 YP_002997249.1 CDS SDEG_1540 NC_012891.1 1493257 1493805 R similar to type II DNA modification methyltransferase [Streptococcus pyogenes MGAS315]; type II DNA modification methyltransferase complement(1493257..1493805) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111630 YP_002997250.1 CDS asnA NC_012891.1 1493990 1494982 R catalyzes the formation of asparagine from aspartate and ammonia; asparagine synthetase AsnA complement(1493990..1494982) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112138 YP_002997251.1 CDS arcC NC_012891.1 1495309 1496259 R catalyzes the reversible synthesis of carbamate and ATP from carbamoyl phosphate and ADP; carbamate kinase complement(1495309..1496259) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112348 YP_002997252.1 CDS SDEG_1543 NC_012891.1 1496749 1497705 D similar to transposase [Streptococcus pneumoniae SP9-BS68]; transposase 1496749..1497705 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112333 YP_002997253.1 CDS SDEG_1544 NC_012891.1 1497893 1499224 R similar to hypothetical protein M5005 Spy 1271 [Streptococcus pyogenes MGAS5005]; hypothetical protein complement(1497893..1499224) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112139 YP_002997254.1 CDS SDEG_1545 NC_012891.1 1499241 1500791 R similar to arginine/ornithine antiporter [Streptococcus pyogenes MGAS5005]; arginine/ornithine antiporter complement(1499241..1500791) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112140 YP_002997255.1 CDS arcB NC_012891.1 1500904 1501917 R catalyzes the formation of ornithine and carbamylphosphate from citrulline in the arginine catabolic pathway; ornithine carbamoyltransferase complement(1500904..1501917) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112141 YP_002997256.1 CDS SDEG_1547 NC_012891.1 1502041 1502382 R similar to COG0454, Histone acetyltransferase HPA2 and related acetyltransferases [Streptococcus pyogenes M49 591]; histone acetyltransferase HPA2-like protein complement(1502041..1502382) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112332 YP_002997257.1 CDS arcA NC_012891.1 1502482 1503717 R catalyzes the degradation of arginine to citruline and ammonia; arginine deiminase complement(1502482..1503717) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112142 YP_002997258.1 CDS SDEG_1549 NC_012891.1 1503993 1504673 R similar to transcription regulator crp family [Streptococcus pyogenes MGAS10394]; Crp family transcriptional regulator complement(1503993..1504673) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112331 YP_002997259.1 CDS argR NC_012891.1 1504815 1505288 D similar to arginine repressor argR [Streptococcus pyogenes MGAS10394]; arginine repressor 1504815..1505288 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112143 YP_002997260.1 CDS SDEG_1551 NC_012891.1 1505466 1506182 R similar to hypothetical protein M28 Spy1216 [Streptococcus pyogenes MGAS6180]; hypothetical protein complement(1505466..1506182) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112334 YP_002997261.1 CDS SDEG_1552 NC_012891.1 1506196 1507275 R similar to hypothetical cytosolic protein [Streptococcus pyogenes MGAS5005]; hypothetical protein complement(1506196..1507275) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112144 YP_002997262.1 CDS yesM NC_012891.1 1507348 1509081 R similar to two-component sensor kinase [Streptococcus pyogenes MGAS5005]; two-component sensor kinase complement(1507348..1509081) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112145 YP_002997263.1 CDS yesN NC_012891.1 1509078 1509818 R similar to two-component response regulator YesN [Streptococcus pyogenes MGAS10394]; two-component response regulator complement(1509078..1509818) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111961 YP_002997264.1 CDS msrA NC_012891.1 1509906 1511012 R similar to bifunctional methionine sulfoxide reductase A/B protein [Streptococcus pyogenes MGAS6180]; bifunctional methionine sulfoxide reductase A/B complement(1509906..1511012) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111964 YP_002997265.1 CDS tipA NC_012891.1 1511055 1511648 R similar to thiol:disulfide interchange protein [Streptococcus pyogenes MGAS5005]; disulfide interchange protein complement(1511055..1511648) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110944 YP_002997266.1 CDS ccdA NC_012891.1 1511690 1512400 R similar to cytochrome c-type biogenesis protein [Streptococcus pyogenes str. Manfredo]; cytochrome c-type biogenesis protein complement(1511690..1512400) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110524 YP_002997267.1 CDS corA NC_012891.1 1512620 1513552 R similar to magnesium and cobalt transport protein [Streptococcus pyogenes MGAS10394]; magnesium and cobalt transport protein complement(1512620..1513552) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111608 YP_002997268.1 CDS SDEG_1559 NC_012891.1 1513644 1514624 R similar to oxidoreductase [Streptococcus pyogenes str. Manfredo]; oxidoreductase complement(1513644..1514624) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111641 YP_002997269.1 CDS SDEG_1560 NC_012891.1 1515191 1515382 D similar to hypothetical protein M6 Spy1308 [Streptococcus pyogenes MGAS10394]; hypothetical protein 1515191..1515382 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112146 YP_002997270.1 CDS SDEG_1561 NC_012891.1 1515523 1516392 D similar to hypothetical protein SpyM50565 [Streptococcus pyogenes str. Manfredo]; hypothetical protein 1515523..1516392 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112147 YP_002997271.1 CDS valS NC_012891.1 1516608 1519256 R valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain; valyl-tRNA synthetase complement(1516608..1519256) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112148 YP_002997272.1 CDS SDEG_1563 NC_012891.1 1519258 1519842 R similar to hypothetical protein M6 Spy1311 [Streptococcus pyogenes MGAS10394]; hypothetical protein complement(1519258..1519842) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111947 YP_002997273.1 CDS SDEG_1564 NC_012891.1 1519818 1520408 R similar to acetyltransferase GNAT family [Streptococcus agalactiae 2603V/R]; GNAT family acetyltransferase complement(1519818..1520408) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112149 YP_002997274.1 CDS SDEG_1565 NC_012891.1 1520422 1520805 R similar to glyoxalase/bleomycin resistance protein/dioxygenase [Streptococcus suis 89/1591]; bleomycin resistance protein complement(1520422..1520805) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112150 YP_002997275.1 CDS SDEG_1566 NC_012891.1 1521160 1521555 R similar to hypothetical protein SPy 1571 [Streptococcus pyogenes M1 GAS]; hypothetical protein complement(1521160..1521555) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112151 YP_002997276.1 CDS SDEG_1567 NC_012891.1 1521576 1521830 R similar to hypothetical protein M6 Spy1314 [Streptococcus pyogenes MGAS10394]; hypothetical protein complement(1521576..1521830) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112152 YP_002997277.1 CDS SDEG_1568 NC_012891.1 1522058 1522492 D similar to hypothetical protein CLOBAR 02811 [Clostridium bartlettii DSM 16795]; hypothetical protein 1522058..1522492 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112153 YP_002997278.1 CDS norM2 NC_012891.1 1522506 1523873 D similar to MOP/MATE family multidrug-resistance efflux pump NorM [Fusobacterium nucleatum subsp. polymorphum ATCC 10953]; MOP/MATE family multidrug-resistance efflux pumpNorM 1522506..1523873 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112154 YP_002997279.1 CDS aroA.2 NC_012891.1 1524545 1525297 D catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate; 3-deoxy-7-phosphoheptulonate synthase 1524545..1525297 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112155 YP_002997280.1 CDS aroB NC_012891.1 1525347 1526426 D catalyzes the formation of 3-dehydroquinate from 3-deoxy-arabino-heptulonate 7-phosphate; functions in aromatic amino acid biosynthesis; 3-dehydroquinate synthase 1525347..1526426 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112338 YP_002997281.1 CDS SDEG_1573 NC_012891.1 1526842 1528824 R similar to adhesion protein [Streptococcus uberis]; adhesion protein complement(1526842..1528824) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112339 YP_002997282.1 CDS SDEG_1574 NC_012891.1 1528970 1529143 D similar to hypothetical protein LSL 1395 [Lactobacillus salivarius UCC118]; hypothetical protein 1528970..1529143 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112156 YP_002997283.1 CDS SDEG_1575 NC_012891.1 1529190 1530098 R similar to predicted permease [Streptococcus suis 05ZYH33]; permease complement(1529190..1530098) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112157 YP_002997284.1 CDS aroE NC_012891.1 1530240 1531160 R similar to shikimate 5-dehydrogenase [Streptococcus pyogenes M1 GAS]; shikimate 5-dehydrogenase complement(1530240..1531160) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112158 YP_002997285.1 CDS lacZ NC_012891.1 1531259 1534759 R similar to beta-galactosidase [Streptococcus pyogenes MGAS2096]; beta-galactosidase complement(1531259..1534759) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112341 YP_002997286.1 CDS yesN NC_012891.1 1534689 1536173 R similar to two-component response regulator [Streptococcus pyogenes MGAS6180]; two-component response regulator complement(1534689..1536173) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110888 YP_002997287.1 CDS yesM NC_012891.1 1536173 1537900 R similar to two-component sensor kinase [Streptococcus pyogenes MGAS6180]; two-component sensor kinase complement(1536173..1537900) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111965 YP_002997288.1 CDS SDEG_1580 NC_012891.1 1537887 1538492 R similar to hypothetical membrane spanning protein [Streptococcus pyogenes MGAS10394]; hypothetical protein complement(1537887..1538492) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111962 YP_002997289.1 CDS SDEG_1581 NC_012891.1 1538800 1540245 R similar to sugar-binding protein [Streptococcus pyogenes MGAS10750]; sugar-binding protein complement(1538800..1540245) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112159 YP_002997290.1 CDS SDEG_1582 NC_012891.1 1540325 1541251 R similar to binding-protein-dependent transport system membrane protein [Streptococcus pyogenes str. Manfredo]; binding-protein-dependent transport system membrane protein complement(1540325..1541251) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112160 YP_002997291.1 CDS SDEG_1583 NC_012891.1 1541261 1542259 R similar to sugar transport system permease protein [Streptococcus pyogenes MGAS10270]; sugar transport system permease complement(1541261..1542259) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112161 YP_002997292.1 CDS SDEG_1584 NC_012891.1 1542362 1543285 D similar to glucokinase [Streptococcus pyogenes MGAS10394]; glucokinase 1542362..1543285 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112162 YP_002997293.1 CDS SDEG_1585 NC_012891.1 1543289 1545463 D similar to alpha-1,2-mannosidase [Geobacillus sp. Y412MC10]; alpha-1,2-mannosidase 1543289..1545463 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112163 YP_002997294.1 CDS SDEG_1586 NC_012891.1 1545624 1546316 R similar to two-component response regulator histidine kinase [Streptococcus pyogenes MGAS315]; two-component response regulator histidine kinase complement(1545624..1546316) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112164 YP_002997295.1 CDS SDEG_1587 NC_012891.1 1546689 1548080 R similar tobeta-glucosidase [Streptococcus pyogenes MGAS5005]; beta-glucosidase complement(1546689..1548080) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112165 YP_002997296.1 CDS hyl NC_012891.1 1548105 1549799 R similar to hyaluronoglucosaminidase [Streptococcus pyogenes MGAS10394]; hyaluronoglucosaminidase complement(1548105..1549799) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112166 YP_002997297.1 CDS SDEG_1589 NC_012891.1 1549850 1550890 R similar to transcriptional regulator GntR family [Streptococcus pyogenes MGAS5005]; GntR family transcriptional regulator complement(1549850..1550890) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112045 YP_002997298.1 CDS SDEG_1590 NC_012891.1 1551022 1552308 D similar tohypothetical protein M28 Spy1357 [Streptococcus pyogenes MGAS6180]; hypothetical protein 1551022..1552308 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112167 YP_002997299.1 CDS SDEG_1591 NC_012891.1 1552323 1555028 D similar toalpha-mannosidase [Streptococcus pyogenes MGAS5005]; alpha-mannosidase 1552323..1555028 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112168 YP_002997300.1 CDS SDEG_1592 NC_012891.1 1555133 1555546 R similar to histone acetyltransferase HPA2 [Streptococcus sanguinis SK36]; histone acetyltransferase HPA2 complement(1555133..1555546) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112169 YP_002997301.1 CDS pat NC_012891.1 1555527 1556147 R similar to phosphinothricin N-acetyltransferase [Streptococcus equi subsp. zooepidemicus MGCS10565]; phosphinothricin N-acetyltransferase complement(1555527..1556147) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112170 YP_002997302.1 CDS SDEG_1594 NC_012891.1 1556989 1557981 R similar to hypothetical protein spyM18 1170 [Streptococcus pyogenes MGAS8232]; hypothetical protein complement(1556989..1557981) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111753 YP_002997303.1 CDS SDEG_1595 NC_012891.1 1558151 1559818 R similar to AMP-dependent synthetase and ligase [Rhodopseudomonas palustris BisA53]; AMP-dependent synthetase and ligase complement(1558151..1559818) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112171 YP_002997304.1 CDS SDEG_1596 NC_012891.1 1559875 1560789 R similar to hypothetical protein CLOHIR 01137 [Clostridium hiranonis DSM 13275]; hypothetical protein complement(1559875..1560789) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112172 YP_002997305.1 CDS SDEG_1597 NC_012891.1 1560786 1561979 R similar to acyl-CoA acetyltransferase FadA [Carnobacterium sp. AT7]; acyl-CoA acetyltransferase complement(1560786..1561979) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112173 YP_002997306.1 CDS SDEG_1598 NC_012891.1 1562017 1564242 R similar to fatty oxidation complex protein [Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305]; fatty oxidation complex protein complement(1562017..1564242) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112174 YP_002997307.1 CDS SDEG_1599 NC_012891.1 1564320 1564442 D similar to hypothetical protein SSU98 0605 [Streptococcus suis 98HAH33]; hypothetical protein 1564320..1564442 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112175 YP_002997308.1 CDS SDEG_1600 NC_012891.1 1564530 1564766 D similar to transposase IS4 [Streptococcus suis 89/1591]; transposase IS4 1564530..1564766 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112176 YP_002997309.1 CDS SDEG_1601 NC_012891.1 1565172 1565918 R no hit; hypothetical protein complement(1565172..1565918) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112177 YP_002997310.1 CDS SDEG_1602 NC_012891.1 1565920 1566849 R similar to ABC transporter ATP-binding protein [Listeria monocytogenes str. 4b F2365]; ABC transporter ATP-binding protein complement(1565920..1566849) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112178 YP_002997311.1 CDS SDEG_1603 NC_012891.1 1567172 1567315 R similar to hypothetical protein PEPMIC 00589 [Peptostreptococcus micros ATCC 33270]; hypothetical protein complement(1567172..1567315) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112179 YP_002997312.1 CDS SDEG_1604 NC_012891.1 1567309 1568667 R similar to RNA methyltransferase [Streptococcus pyogenes M1 GAS]; RNA methyltransferase complement(1567309..1568667) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112180 YP_002997313.1 CDS SDEG_1605 NC_012891.1 1568857 1569039 R similar to unknown phage protein [Streptococcus pyogenes MGAS10394]; phage protein complement(1568857..1569039) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112181 YP_002997314.1 CDS SDEG_1606 NC_012891.1 1569210 1569584 D similar to protein gp30 [bacteriophage A118] [Listeria monocytogenes EGD-e]; protein gp30 1569210..1569584 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112182 YP_002997315.1 CDS SDEG_1607 NC_012891.1 1569584 1570186 D similar to hypothetical protein PEPE 1706 [Pediococcus pentosaceus ATCC 25745]; hypothetical protein 1569584..1570186 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112183 YP_002997316.1 CDS SDEG_1608 NC_012891.1 1570158 1570403 D similar to hypothetical protein phiPH15 gp59 [Streptococcus phage PH15]; hypothetical protein 1570158..1570403 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112184 YP_002997317.1 CDS SDEG_1609 NC_012891.1 1570914 1572263 R similar to prophage LambdaSa2 lysin [Streptococcus agalactiae 2603V/R]; prophage LambdaSa2, lysin complement(1570914..1572263) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112185 YP_002997318.1 CDS SDEG_1610 NC_012891.1 1572265 1572597 R similar to N-acetylmuramoyl-L-alanine amidase [Streptococcus pyogenes MGAS5005]; N-acetylmuramoyl-L-alanine amidase complement(1572265..1572597) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112186 YP_002997319.1 CDS SDEG_1611 NC_012891.1 1572597 1572920 R similar to phage protein [bacteriophage 10750.2]; phage protein complement(1572597..1572920) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112187 YP_002997320.1 CDS SDEG_1612 NC_012891.1 1572933 1573097 R similar to phage protein [Streptococcus pyogenes MGAS5005]; phage protein complement(1572933..1573097) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112188 YP_002997321.1 CDS SDEG_1613 NC_012891.1 1573069 1573419 R similar to hypothetical protein SpyM3 1309 [Streptococcus pyogenes MGAS315]; hypothetical protein complement(1573069..1573419) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112189 YP_002997322.1 CDS SDEG_1614 NC_012891.1 1573435 1575312 R similar to prophage LambdaSa1 minor structural protein [Streptococcus agalactiae 18RS21]; prophage LambdaSa1, minor structural protein complement(1573435..1575312) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112190 YP_002997323.1 CDS SDEG_1615 NC_012891.1 1575323 1578691 R similar to phage protein [Streptococcus pyogenes MGAS5005]; phage protein complement(1575323..1578691) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112191 YP_002997324.1 CDS SDEG_1616 NC_012891.1 1578692 1580176 R similar to phage tail protein [bacteriophage 10750.2]; phage tail protein complement(1578692..1580176) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112192 YP_002997325.1 CDS SDEG_1617 NC_012891.1 1580177 1581361 R similar to platlet-binding protein minor tail fiber protein - phage associated [Streptococcus pyogenes MGAS315]; platlet-binding protein, minor tailfiber protein complement(1580177..1581361) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112193 YP_002997326.1 CDS SDEG_1618 NC_012891.1 1581580 1582140 R similar to endodeoxyribonuclease [Lactococcus phage r1t]; endodeoxyribonuclease complement(1581580..1582140) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112194 YP_002997327.1 CDS SDEG_1619 NC_012891.1 1582206 1582910 R similar to phage protein [bacteriophage 10750.2]; phage protein complement(1582206..1582910) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112195 YP_002997328.1 CDS SDEG_1620 NC_012891.1 1582903 1583361 R similar to phage protein [Streptococcus pyogenes MGAS5005]; phage protein complement(1582903..1583361) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112196 YP_002997329.1 CDS SDEG_1621 NC_012891.1 1583334 1583651 R similar to phage protein [Streptococcus pyogenes MGAS5005]; phage protein complement(1583334..1583651) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112197 YP_002997330.1 CDS SDEG_1622 NC_012891.1 1583663 1584169 R similar to antigen A [Streptococcus pyogenes MGAS5005]; antigen A complement(1583663..1584169) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112198 YP_002997331.1 CDS SDEG_1623 NC_012891.1 1584181 1584591 R similar to antigen B [Streptococcus pyogenes MGAS5005]; antigen B complement(1584181..1584591) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112199 YP_002997332.1 CDS SDEG_1624 NC_012891.1 1584593 1584988 R similar to antigen C [bacteriophage 10750.2]; antigen C complement(1584593..1584988) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112200 YP_002997333.1 CDS SDEG_1625 NC_012891.1 1584985 1585296 R similar to phage protein [bacteriophage 10750.2]; phage protein complement(1584985..1585296) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112201 YP_002997334.1 CDS SDEG_1626 NC_012891.1 1585293 1585637 R similar to hypothetical protein SpyM3 1320 [Streptococcus pyogenes MGAS315]; hypothetical protein complement(1585293..1585637) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112202 YP_002997335.1 CDS SDEG_1627 NC_012891.1 1585651 1585944 R similar to phage protein [bacteriophage 10750.2]; phage protein complement(1585651..1585944) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112203 YP_002997336.1 CDS SDEG_1628 NC_012891.1 1585956 1586846 R similar to hypothetical protein SpyM3_1322 [Streptococcus pyogenes MGAS315]; hypothetical protein complement(1585956..1586846) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112204 YP_002997337.1 CDS SDEG_1629 NC_012891.1 1586864 1587475 R similar to phage scaffold protein [bacteriophage 10750.2]; phage scaffold protein complement(1586864..1587475) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112205 YP_002997338.1 CDS SDEG_1630 NC_012891.1 1587676 1587903 R similar to phage protein [bacteriophage 10750.2]; phage protein complement(1587676..1587903) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112206 YP_002997339.1 CDS SDEG_1631 NC_012891.1 1587910 1588818 R similar to phage protein [bacteriophage 10750.2]; phage protein complement(1587910..1588818) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112207 YP_002997340.1 CDS SDEG_1632 NC_012891.1 1588787 1590112 R similar to portal protein [bacteriophage 10750.2]; portal protein complement(1588787..1590112) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112208 YP_002997341.1 CDS SDEG_1633 NC_012891.1 1590112 1591386 R similar to Terminase large subunit [bacteriophage 10750.2]; terminase large subunit complement(1590112..1591386) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112209 YP_002997342.1 CDS SDEG_1634 NC_012891.1 1591376 1591756 R similar to phage protein [bacteriophage 10750.2]; phage protein complement(1591376..1591756) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112210 YP_002997343.1 CDS SDEG_1635 NC_012891.1 1591842 1591994 D similar to phage protein [Streptococcus pyogenes MGAS10750]; phage protein 1591842..1591994 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112211 YP_002997344.1 CDS SDEG_1636 NC_012891.1 1592285 1592725 R similar to phage encoded transcriptional regulator ArpU family [bacteriophage 10750.2]; ArpU family phage encoded transcriptional regulator complement(1592285..1592725) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112212 YP_002997345.1 CDS SDEG_1637 NC_012891.1 1592765 1592860 R similar to hypothetical protein MGAS9429 Spy0819 [bacteriophage 9429.2]; hypothetical protein complement(1592765..1592860) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112213 YP_002997346.1 CDS SDEG_1638 NC_012891.1 1593083 1593616 R similar to hypothetical protein SpyM50655 [Streptococcus pyogenes str. Manfredo]; hypothetical protein complement(1593083..1593616) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112214 YP_002997347.1 CDS SDEG_1639 NC_012891.1 1593606 1593854 R no hit; hypothetical protein complement(1593606..1593854) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112215 YP_002997348.1 CDS SDEG_1640 NC_012891.1 1593858 1594127 R similar to phage protein [Streptococcus pyogenes MGAS5005]; phage protein complement(1593858..1594127) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112216 YP_002997349.1 CDS SDEG_1641 NC_012891.1 1594124 1594528 R similar to hypothetical protein SpyoM01000037 [Streptococcus pyogenes M49 591]; hypothetical protein complement(1594124..1594528) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112379 YP_002997350.1 CDS orf80 NC_012891.1 1594525 1594737 R similar to Orf80 [bacteriophage phi31.1]; phage protein orf80 complement(1594525..1594737) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112380 YP_002997351.1 CDS SDEG_1643 NC_012891.1 1594787 1595122 R no hit; hypothetical protein complement(1594787..1595122) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111745 YP_002997352.1 CDS SDEG_1644 NC_012891.1 1595115 1595402 R similar to hypothetical protein spyM18 1285 [Streptococcus pyogenes MGAS8232]; hypothetical protein complement(1595115..1595402) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112381 YP_002997353.1 CDS SDEG_1645 NC_012891.1 1595399 1595647 R similar to hypothetical protein SpyM3 1246 [Streptococcus pyogenes MGAS315]; hypothetical protein complement(1595399..1595647) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112382 YP_002997354.1 CDS SDEG_1646 NC_012891.1 1595644 1596000 R similar to phage protein [bacteriophage 10750.1]; phage protein complement(1595644..1596000) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112383 YP_002997355.1 CDS SDEG_1647 NC_012891.1 1595997 1596437 R similar to phage protein [Streptococcus pyogenes MGAS6180]; phage protein complement(1595997..1596437) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112384 YP_002997356.1 CDS SDEG_1648 NC_012891.1 1596437 1596640 R similar to phage protein [Streptococcus pyogenes MGAS6180]; phage protein complement(1596437..1596640) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112385 YP_002997357.1 CDS ssb NC_012891.1 1596646 1597065 R similar to single strand binding protein [Streptococcus pyogenes MGAS8232]; single strand binding protein complement(1596646..1597065) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112386 YP_002997358.1 CDS ssb1 NC_012891.1 1597058 1597732 R similar to phage single-strand DNA binding protein [Streptococcus pyogenes MGAS5005]; phage single-strand DNA-binding protein complement(1597058..1597732) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110503 YP_002997359.1 CDS SDEG_1651 NC_012891.1 1597733 1598215 R similar to phage protein [Streptococcus pyogenes MGAS5005]; phage protein complement(1597733..1598215) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110504 YP_002997360.1 CDS SDEG_1652 NC_012891.1 1598236 1598490 R similar to hypothetical protein SpyM3 1252 [Streptococcus pyogenes MGAS315]; hypothetical protein complement(1598236..1598490) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112387 YP_002997361.1 CDS SDEG_1653 NC_012891.1 1598477 1598827 R similar to hypothetical protein spyM18 1799 [Streptococcus pyogenes MGAS8232]; hypothetical protein complement(1598477..1598827) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112388 YP_002997362.1 CDS SDEG_1654 NC_012891.1 1598837 1598974 R similar to phage protein [Streptococcus pyogenes MGAS5005]; phage protein complement(1598837..1598974) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112389 YP_002997363.1 CDS SDEG_1655 NC_012891.1 1598965 1599747 R similar to phage DNA replication protein [Streptococcus pyogenes str. Manfredo]; phage DNA replication protein complement(1598965..1599747) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112390 YP_002997364.1 CDS SDEG_1656 NC_012891.1 1599734 1600549 R similar to COG3935, primosome component and related proteins [Streptococcus pyogenes M49 591]; primosome component and related proteins complement(1599734..1600549) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112391 YP_002997365.1 CDS SDEG_1657 NC_012891.1 1600550 1600756 R similar to phage protein [bacteriophage 10750.1]; phage protein complement(1600550..1600756) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112392 YP_002997366.1 CDS SDEG_1658 NC_012891.1 1600737 1600877 R similar to phage protein [Streptococcus pyogenes MGAS6180]; phage protein complement(1600737..1600877) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112393 YP_002997367.1 CDS SDEG_1659 NC_012891.1 1600908 1601159 R similar to phage protein [bacteriophage 10750.2]; phage protein complement(1600908..1601159) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112394 YP_002997368.1 CDS SDEG_1660 NC_012891.1 1601289 1601501 R similar to hypothetical protein SpyM50475 [Streptococcus pyogenes str. Manfredo]; hypothetical protein complement(1601289..1601501) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112395 YP_002997369.1 CDS SDEG_1661 NC_012891.1 1601698 1602039 D similar to hypothetical protein SpyM50474 [Streptococcus pyogenes str. Manfredo]; hypothetical protein 1601698..1602039 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112396 YP_002997370.1 CDS SDEG_1662 NC_012891.1 1602023 1602400 D similar to cI-like repressor metallo-prtoeinase motif - phage associated [Streptococcus pyogenes MGAS315]; cI-like repressor 1602023..1602400 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112397 YP_002997371.1 CDS SDEG_1663 NC_012891.1 1602409 1603095 D similar to phage protein [Streptococcus pyogenes MGAS10750]; phage protein 1602409..1603095 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112398 YP_002997372.1 CDS SDEG_1664 NC_012891.1 1603132 1603281 D similar to hypothetical protein SPs0508 [Streptococcus pyogenes SSI-1]; hypothetical protein 1603132..1603281 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112399 YP_002997373.1 CDS int NC_012891.1 1603208 1604434 D similar to phage integrase [Streptococcus pyogenes MGAS8232]; phage integrase 1603208..1604434 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112400 YP_002997374.1 CDS recX NC_012891.1 1604582 1605358 D binds RecA and inhibits RecA-mediated DNA strand exchange and ATP hydrolysis and coprotease activities; recombination regulator RecX 1604582..1605358 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110870 YP_002997375.1 CDS SDEG_1667 NC_012891.1 1605440 1605973 D similar to hypothetical cytosolic protein [Streptococcus pyogenes MGAS10394]; hypothetical protein 1605440..1605973 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111040 YP_002997376.1 CDS SDEG_1668 NC_012891.1 1606027 1606338 D similar to hypothetical protein Sez 1543 [Streptococcus equi subsp. zooepidemicus MGCS10565]; hypothetical protein 1606027..1606338 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112401 YP_002997377.1 CDS SDEG_1680 NC_012891.1 1612537 1613655 R similar to transposase [Streptococcus pyogenes MGAS10270]; transposase complement(1612537..1613655) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112413 YP_002997378.1 CDS SDEG_1681 NC_012891.1 1613779 1614327 R similar to ribosome-associated factor Y [Streptococcus pyogenes MGAS10394]; ribosome-associated factor Y complement(1613779..1614327) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112414 YP_002997379.1 CDS comFC NC_012891.1 1614407 1615072 R similar to late competence protein [Streptococcus pyogenes str. Manfredo]; late competence protein complement(1614407..1615072) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112415 YP_002997380.1 CDS comFA NC_012891.1 1615044 1616369 R similar to late competence protein required for DNA uptake [Streptococcus pyogenes M1 GAS]; late competence protein required for DNA uptake complement(1615044..1616369) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111636 YP_002997381.1 CDS SDEG_1684 NC_012891.1 1616425 1617063 D similar to hypothetical protein Sez 1548 [Streptococcus equi subsp. zooepidemicus MGCS10565]; Xaa-Pro dipeptidase 1616425..1617063 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111635 YP_002997382.1 CDS cysM NC_012891.1 1617167 1618102 D similar to cysteine synthase [Streptococcus pyogenes MGAS10750]; cysteine synthase 1617167..1618102 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112416 YP_002997383.1 CDS SDEG_1686 NC_012891.1 1618255 1618614 R similar to S1-type RNA-binding domain [Streptococcus pyogenes MGAS10750]; hypothetical protein complement(1618255..1618614) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111657 YP_002997384.1 CDS SDEG_1687 NC_012891.1 1618614 1620026 R similar to cyclophilin-type protein [Streptococcus pyogenes SSI-1]; cyclophilin-type protein complement(1618614..1620026) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112417 YP_002997385.1 CDS yvqC NC_012891.1 1620051 1620698 R similar to two-component response regulator [Streptococcus pyogenes SSI-1]; two-component response regulator complement(1620051..1620698) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112418 YP_002997386.1 CDS yvqE NC_012891.1 1620685 1621689 R similar to two-component sensor protein yvqE [Streptococcus pyogenes MGAS10394]; two-component sensor protein yvqE complement(1620685..1621689) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111969 YP_002997387.1 CDS yvqF NC_012891.1 1621686 1622378 R similar to transporter yvqF [Streptococcus pyogenes MGAS10394]; transporter yvqF complement(1621686..1622378) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111970 YP_002997388.1 CDS stk1 NC_012891.1 1622505 1624400 R similar to serine/threonine-protein kinase [Streptococcus pyogenes str. Manfredo]; serine/threonine-protein kinase complement(1622505..1624400) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111971 YP_002997389.1 CDS pppL NC_012891.1 1624397 1625137 R similar to protein phosphatase 2C [Streptococcus pyogenes MGAS10394]; protein phosphatase 2C complement(1624397..1625137) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110507 YP_002997390.1 CDS sunL NC_012891.1 1625175 1626533 R similar to 16S rRNA m(5)C 967 methyltransferase [Streptococcus pyogenes MGAS6180]; 16S rRNA m(5)C 967 methyltransferase complement(1625175..1626533) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111304 YP_002997391.1 CDS fmt NC_012891.1 1626487 1627422 R modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet) which is important in translation initiation; inactivation of this gene in Escherichia coli severely impairs growth; methionyl-tRNA formyltransferase complement(1626487..1627422) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110511 YP_002997392.1 CDS priA NC_012891.1 1627487 1629871 R binding of PriA to forked DNA starts the assembly of the primosome, also possesses 3'-5' helicase activity; primosome assembly protein PriA complement(1627487..1629871) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111900 YP_002997393.1 CDS SDEG_1696 NC_012891.1 1629935 1630252 R Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits; DNA-directed RNA polymerase subunit omega complement(1629935..1630252) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111309 YP_002997394.1 CDS gmk NC_012891.1 1630268 1630900 R Essential for recycling GMP and indirectly, cGMP; guanylate kinase complement(1630268..1630900) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112419 YP_002997395.1 CDS SDEG_1698 NC_012891.1 1631010 1632617 R similar to phosphohydrolase [Streptococcus pyogenes str. Manfredo]; hypothetical protein complement(1631010..1632617) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112015 YP_002997396.1 CDS SDEG_1699 NC_012891.1 1632747 1633736 R similar to transcriptional regulators LysR family [Streptococcus pyogenes MGAS10394]; LysR family transcriptional regulator complement(1632747..1633736) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112420 YP_002997397.1 CDS atoB NC_012891.1 1633842 1635029 D similar to acetyl-CoA acetyltransferase [Streptococcus pyogenes MGAS2096]; acetyl-CoA acetyltransferase 1633842..1635029 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112421 YP_002997398.1 CDS atoD.1 NC_012891.1 1635113 1635703 D similar to acetate CoA-transferase alpha subunit [Streptococcus pyogenes MGAS5005]; acetate CoA-transferase subunit alpha 1635113..1635703 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112355 YP_002997399.1 CDS atoA NC_012891.1 1635813 1636364 D similar to acetate CoA-transferase beta subunit [Streptococcus pyogenes MGAS5005]; acetate CoA-transferase subunit beta 1635813..1636364 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112356 YP_002997400.1 CDS SDEG_1703 NC_012891.1 1636397 1636864 D similar to short chain dehydrogenase [Streptococcus pyogenes MGAS6180]; short chain dehydrogenase 1636397..1636864 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112354 YP_002997401.1 CDS SDEG_1704 NC_012891.1 1636867 1637817 D similar to D-beta-hydroxybutyrate permease [Streptococcus pyogenes MGAS10750]; D-beta-hydroxybutyrate permease 1636867..1637817 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112422 YP_002997402.1 CDS luxS NC_012891.1 1638184 1638666 D catalyzes the hydrolysis of S-ribosylhomocysteine to homocysteine and autoinducer-2; S-ribosylhomocysteinase 1638184..1638666 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112423 YP_002997403.1 CDS SDEG_1706 NC_012891.1 1638780 1640261 R similar to hypothetical protein spyM18 1655 [Streptococcus pyogenes MGAS8232]; hypothetical protein complement(1638780..1640261) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110912 YP_002997404.1 CDS SDEG_1707 NC_012891.1 1640275 1641429 R similar to methyltransferase [Streptococcus pyogenes MGAS10270]; methyltransferase complement(1640275..1641429) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112424 YP_002997405.1 CDS SDEG_1708 NC_012891.1 1641874 1642200 R similar to cell division initiation protein [Streptococcus pyogenes MGAS5005]; cell division initiation protein complement(1641874..1642200) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112425 YP_002997406.1 CDS SDEG_1709 NC_012891.1 1642322 1642837 R similar to hypothetical protein spyM18 1659 [Streptococcus pyogenes MGAS8232]; hypothetical protein complement(1642322..1642837) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112426 YP_002997407.1 CDS recU NC_012891.1 1642918 1643526 D functions in homologous recombination, DNA repair, and chromosome segregation; binds preferentially to three- and four-stranded DNA intermediates; introduces specific nick sites in four-stranded DNA substrates; functions similarly to Escherichia coli RuvC; Holliday junction-specific endonuclease 1642918..1643526 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112427 YP_002997408.1 CDS pbp1A NC_012891.1 1643513 1645687 D similar to multimodular transpeptidase-transglycosylase PBP 1A [Streptococcus pyogenes MGAS10750]; multimodular transpeptidase-transglycosylase 1643513..1645687 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111039 YP_002997409.1 CDS pepC NC_012891.1 1645733 1647064 R similar to aminopeptidase C [Streptococcus pyogenes MGAS315]; aminopeptidase C complement(1645733..1647064) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111754 YP_002997410.1 CDS nadE NC_012891.1 1647245 1648111 R catalyzes the formation of nicotinamide adenine dinucleotide (NAD) from nicotinic acid adenine dinucleotide (NAAD) using either ammonia or glutamine as the amide donor and ATP; ammonia-utilizing enzymes include the ones from Bacillus and Escherichia coli while glutamine-utilizing enzymes include the Mycobacterial one; forms homodimers; NAD synthetase complement(1647245..1648111) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111274 YP_002997411.1 CDS SDEG_1714 NC_012891.1 1648071 1649525 R catalyzes the formation of 5-phospho-alpha-D-ribose 1-diphosphate and nicotinate from nicotinate D-ribonucleotide and diphosphate; nicotinate phosphoribosyltransferase complement(1648071..1649525) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111705 YP_002997412.1 CDS SDEG_1715 NC_012891.1 1649695 1651086 R similar to amino acid permease [Streptococcus pyogenes MGAS6180]; amino acid permease complement(1649695..1651086) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112428 YP_002997413.1 CDS SDEG_1716 NC_012891.1 1651236 1652153 R similar to thioredoxin reductase [Streptococcus pyogenes MGAS10394]; thioredoxin reductase complement(1651236..1652153) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112429 YP_002997414.1 CDS SDEG_1717 NC_012891.1 1652216 1652440 R similar to hypothetical protein SpyM50430 [Streptococcus pyogenes str. Manfredo]; hypothetical protein complement(1652216..1652440) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112430 YP_002997415.1 CDS SDEG_1718 NC_012891.1 1652544 1653290 R similar to transporter [Streptococcus pyogenes MGAS6180]; transporter complement(1652544..1653290) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112431 YP_002997416.1 CDS SDEG_1719 NC_012891.1 1653287 1654090 R similar to amino acid ABC transporter permease protein [Streptococcus pyogenes MGAS10394]; amino acid ABC transporter permease complement(1653287..1654090) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112432 YP_002997417.1 CDS SDEG_1720 NC_012891.1 1654234 1655067 R similar to amino-acid ABC transporter extracellular-binding protein precursor [Streptococcus equi subsp. zooepidemicus MGCS10565]; amino acid ABC transporter extracellular-binding protein complement(1654234..1655067) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112433 YP_002997418.1 CDS SDEG_1721 NC_012891.1 1655264 1656607 R similar to ATP-dependent RNA helicase [Streptococcus pyogenes MGAS10394]; ATP-dependent RNA helicase complement(1655264..1656607) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112434 YP_002997419.1 CDS SDEG_1722 NC_012891.1 1656606 1656755 D similar to hypothetical protein M6 Spy1410 [Streptococcus pyogenes MGAS10394]; hypothetical protein 1656606..1656755 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112435 YP_002997420.1 CDS mraY NC_012891.1 1656761 1657771 R First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; phospho-N-acetylmuramoyl-pentapeptide- transferase complement(1656761..1657771) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112436 YP_002997421.1 CDS ftsI NC_012891.1 1657773 1660028 R similar to division specific DD-transpeptidase [Streptococcus pyogenes MGAS10394]; division specific D,D-transpeptidase complement(1657773..1660028) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110941 YP_002997422.1 CDS ftsL NC_012891.1 1660032 1660385 R similar to cell division protein [Streptococcus pyogenes MGAS315]; cell division protein complement(1660032..1660385) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111918 YP_002997423.1 CDS mraW NC_012891.1 1660360 1661373 R similar to S-adenosyl-methyltransferase mraW [Streptococcus pyogenes MGAS10750]; S-adenosyl-methyltransferase MraW complement(1660360..1661373) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111920 YP_002997424.1 CDS SDEG_1727 NC_012891.1 1661426 1661509 R similar to hypothetical protein M5005 Spy 1369 [Streptococcus pyogenes MGAS5005]; hypothetical protein complement(1661426..1661509) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110940 YP_002997425.1 CDS SDEG_1728 NC_012891.1 1661609 1661782 R similar to hypothetical protein M6 Spy1417 [Streptococcus pyogenes MGAS10394]; hypothetical protein complement(1661609..1661782) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112437 YP_002997426.1 CDS SDEG_1729 NC_012891.1 1661733 1661876 R similar to hypothetical protein MGAS10750 Spy1479 [Streptococcus pyogenes MGAS10750]; hypothetical protein complement(1661733..1661876) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112438 YP_002997427.1 CDS proA NC_012891.1 1661851 1663101 R Catalyzes the phosphorylation of L-glutamate during the proline biosynthesis pathway; gamma-glutamyl phosphate reductase complement(1661851..1663101) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112439 YP_002997428.1 CDS SDEG_1731 NC_012891.1 1663094 1663921 R catalyzes the formation of glutamate 5-phosphate from glutamate in proline biosynthesis; gamma-glutamyl kinase complement(1663094..1663921) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111310 YP_002997429.1 CDS proB NC_012891.1 1663980 1665650 R similar to ABC transporter permease protein [Streptococcus pyogenes MGAS10750]; ABC transporter permease complement(1663980..1665650) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112440 YP_002997430.1 CDS SDEG_1733 NC_012891.1 1665613 1666347 R similar to ABC transporter ATP-binding protein [Streptococcus pyogenes MGAS5005]; ABC transporter ATP-binding protein complement(1665613..1666347) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111311 YP_002997431.1 CDS SDEG_1734 NC_012891.1 1666380 1666646 R similar to hypothetical protein MGAS2096 Spy1397 [Streptococcus pyogenes MGAS2096]; hypothetical protein complement(1666380..1666646) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112441 YP_002997432.1 CDS tkt NC_012891.1 1666839 1669028 R catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase; transketolase complement(1666839..1669028) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112442 YP_002997433.1 CDS SDEG_1736 NC_012891.1 1669042 1669686 R similar to novel fructose-6-phosphate aldolase from Escherichia coli; enzyme from Methanocaldococcus janaschii shows transaldolase activity; translaldolase complement(1669042..1669686) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110525 YP_002997434.1 CDS SDEG_1737 NC_012891.1 1669355 1669729 D similar to conserved hypothetical protein [Listeria monocytogenes str. 1/2a F6854]; hypothetical protein 1669355..1669729 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112443 YP_002997435.1 CDS SDEG_1738 NC_012891.1 1669812 1671341 R similar to trans-acting positive regulator [Streptococcus pyogenes MGAS10750]; trans-acting positive regulator complement(1669812..1671341) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112444 YP_002997436.1 CDS SDEG_1739 NC_012891.1 1671313 1672659 R similar to NADH peroxidase [Streptococcus pyogenes MGAS6180]; NADH peroxidase complement(1671313..1672659) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112445 YP_002997437.1 CDS glpF NC_012891.1 1672764 1673465 R similar to glycerol uptake facilitator protein [Streptococcus pyogenes MGAS10394]; glycerol uptake facilitator protein complement(1672764..1673465) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112446 YP_002997438.1 CDS glpO NC_012891.1 1673467 1675305 R similar to apha-glycerophosphate oxidase [Streptococcus pyogenes MGAS10394]; alpha-glycerophosphate oxidase complement(1673467..1675305) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112007 YP_002997439.1 CDS glpK NC_012891.1 1675321 1676835 R Converts glycerol and ADP to glycerol-3-phosphate and ADP; glycerol kinase complement(1675321..1676835) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112009 YP_002997440.1 CDS SDEG_1743 NC_012891.1 1677176 1677568 R similar to hypothetical protein spyM18 1698 [Streptococcus pyogenes MGAS8232]; hypothetical protein complement(1677176..1677568) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112008 YP_002997441.1 CDS SDEG_1744 NC_012891.1 1677685 1677942 R similar to hypothetical protein M6 Spy1431 [Streptococcus pyogenes MGAS10394]; hypothetical protein complement(1677685..1677942) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112447 YP_002997442.1 CDS glyS NC_012891.1 1678092 1680131 R glycine--tRNA ligase beta chain; glyS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; glycyl-tRNA synthetase subunit beta complement(1678092..1680131) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112448 YP_002997443.1 CDS glyQ NC_012891.1 1680374 1681291 R glycine--tRNA ligase alpha chain; GlyRS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; glycyl-tRNA synthetase subunit alpha complement(1680374..1681291) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112014 YP_002997446.1 CDS SDEG_1749 NC_012891.1 1681663 1682217 R similar to hypothetical protein SPy 1691 [Streptococcus pyogenes M1 GAS]; hypothetical protein complement(1681663..1682217) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112013 YP_002997447.1 CDS SDEG_1750 NC_012891.1 1682328 1683167 R similar to 2,5-diketo-D-gluconic acid reductase [Streptococcus pyogenes MGAS10270]; 2,5-diketo-D-gluconic acid reductase complement(1682328..1683167) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112449 YP_002997448.1 CDS nagA NC_012891.1 1683274 1684425 R similar to N-acetylglucosamine-6-phosphate deacetylase [Streptococcus pyogenes str. Manfredo]; N-acetylglucosamine-6-phosphate deacetylase complement(1683274..1684425) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112450 YP_002997449.1 CDS SDEG_1752 NC_012891.1 1684542 1686191 R similar to sodium-dependent phosphate transporter [Streptococcus pyogenes MGAS10750]; sodium-dependent phosphate transporter complement(1684542..1686191) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111706 YP_002997450.1 CDS SDEG_1753 NC_012891.1 1686413 1687102 D similar to lipoprotein [Streptococcus pyogenes str. Manfredo]; lipoprotein 1686413..1687102 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112451 YP_002997451.1 CDS SDEG_1754 NC_012891.1 1687285 1688127 R similar to DegV family protein [Streptococcus pyogenes MGAS10394]; DegV family fatty acid binding protein complement(1687285..1688127) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112452 YP_002997452.1 CDS SDEG_1755 NC_012891.1 1688428 1688988 D similar to transcriptional regulator TetR family [Streptococcus pyogenes MGAS10394]; TetR family transcriptional regulator 1688428..1688988 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112453 YP_002997453.1 CDS SDEG_1756 NC_012891.1 1689123 1690007 R similar to hydrolase (HAD superfamily) [Streptococcus pyogenes MGAS10394]; HAD superfamily hydrolase complement(1689123..1690007) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112454 YP_002997454.1 CDS SDEG_1757 NC_012891.1 1689952 1690569 R similar to hypothetical membrane spanning protein [Streptococcus pyogenes MGAS10394]; hypothetical protein complement(1689952..1690569) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112455 YP_002997455.1 CDS lacD.1 NC_012891.1 1690763 1691500 R probable ORF of C-terminal portion of tagatose 1,6-diphosphate aldolase [Streptococcus pyogenes MGAS315] resulted from mutation by unknown reason; tagatose 1,6-diphosphate aldolase complement(1690763..1691500) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112456 YP_002997456.1 CDS lacD1 NC_012891.1 1691469 1691876 R probable ORF of N-terminal portion of tagatose 1,6-diphosphate aldolase [Streptococcus pyogenes MGAS315] resulted from mutation by unknown reason; tagatose 1,6-diphosphate aldolase complement(1691469..1691876) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110886 YP_002997457.1 CDS lacC NC_012891.1 1691857 1692810 R similar to tagatose-6-phosphate kinase LacC [Streptococcus equi subsp. zooepidemicus MGCS10565]; tagatose-6-phosphate kinase complement(1691857..1692810) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110887 YP_002997458.1 CDS lacB1 NC_012891.1 1692820 1693335 R catalyzes the interconversion of galactose 6-phosphate to tagatose 6-phosphate; galactose-6-phosphate isomerase subunit LacB complement(1692820..1693335) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110884 YP_002997459.1 CDS lacA1 NC_012891.1 1693350 1693775 R catalyzes the interconversion of galactose 6-phosphate to tagatose; galactose-6-phosphate isomerase subunit LacA complement(1693350..1693775) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110883 YP_002997460.1 CDS SDEG_1763 NC_012891.1 1693854 1694030 D similar to transcriptional regulator [Streptococcus pyogenes MGAS2096]; transcriptional regulator 1693854..1694030 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110882 YP_002997461.1 CDS SDEG_1764 NC_012891.1 1694033 1695484 R similar to sugar phosphotransferase system (PTS)galactitol-specific family IIC component [Streptococcus pyogenes str. Manfredo]; PTS system galactitol-specific family transporter subunit IIC complement(1694033..1695484) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112457 YP_002997462.1 CDS SDEG_1765 NC_012891.1 1695510 1695815 R similar to PTS system galactose-specific IIB component [Streptococcus pyogenes MGAS6180]; PTS system galactose-specific transporter subunit IIB complement(1695510..1695815) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112458 YP_002997463.1 CDS SDEG_1766 NC_012891.1 1695808 1696281 R similar to PTS system enzyme IIA component [Streptococcus pyogenes M1 GAS]; PTS system specific transporter subunit IIA complement(1695808..1696281) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112459 YP_002997464.1 CDS SDEG_1767 NC_012891.1 1696515 1697285 D similar to lactose phosphotransferase system repressor [Streptococcus pyogenes MGAS10394]; lactose phosphotransferase system repressor 1696515..1697285 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110610 YP_002997465.1 CDS SDEG_1768 NC_012891.1 1697312 1697422 R similar to copper chaperone [Streptococcus pyogenes MGAS6180]; copper chaperone complement(1697312..1697422) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110611 YP_002997466.1 CDS copZ NC_012891.1 1697485 1697688 R similar to copper chaperone [Streptococcus pyogenes MGAS6180]; copper chaperone complement(1697485..1697688) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110612 YP_002997467.1 CDS copA NC_012891.1 1697702 1699978 R similar to copper-exporting ATPase [Streptococcus pyogenes MGAS2096]; copper-exporting ATPase complement(1697702..1699978) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111640 YP_002997468.1 CDS SDEG_1771 NC_012891.1 1699933 1700367 R similar to negative transcriptional regulator [Streptococcus pyogenes MGAS8232]; negative transcriptional regulator complement(1699933..1700367) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111639 YP_002997469.1 CDS SDEG_1772 NC_012891.1 1700529 1701323 R similar to transposase [Streptococcus agalactiae]; transposase complement(1700529..1701323) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110613 YP_002997470.1 CDS SDEG_1773 NC_012891.1 1701590 1702219 R similar to hypothetical protein SPy 0130 [Streptococcus pyogenes M1 GAS]; hypothetical protein complement(1701590..1702219) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110614 YP_002997471.1 CDS SDEG_1774 NC_012891.1 1702228 1702497 R similar to hypothetical protein SPy 0129 [Streptococcus pyogenes M1 GAS]; hypothetical protein complement(1702228..1702497) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110615 YP_002997472.1 CDS SDEG_1775 NC_012891.1 1702647 1703579 D similar to transposase IS256 family [Streptococcus agalactiae 2603V/R]; IS256 family transposase 1702647..1703579 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110616 YP_002997473.1 CDS SDEG_1776 NC_012891.1 1703585 1703821 D similar to transposase IS256 family [Streptococcus agalactiae 2603V/R]; IS256 family transposase 1703585..1703821 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110617 YP_002997474.1 CDS SDEG_1777 NC_012891.1 1704055 1704744 R similar to hypothetical protein MGAS2096 Spy0117 [Streptococcus pyogenes MGAS2096]; hypothetical protein complement(1704055..1704744) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110618 YP_002997475.1 CDS eftLSL-B NC_012891.1 1704674 1705393 R similar to sortase B family protein [Streptococcus pyogenes MGAS2096]; sortase complement(1704674..1705393) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110619 YP_002997476.1 CDS SDEG_1779 NC_012891.1 1705416 1706462 R similar to hypothetical protein M28 Spy0109 [Streptococcus pyogenes MGAS6180]; hypothetical protein complement(1705416..1706462) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111867 YP_002997477.1 CDS SDEG_1780 NC_012891.1 1706483 1707004 R similar to signal peptidase I [Streptococcus pyogenes MGAS6180]; signal peptidase I complement(1706483..1707004) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110620 YP_002997478.1 CDS cbp NC_012891.1 1706997 1708523 R similar to collagen binding protein [Streptococcus pyogenes MGAS315]; collagen binding protein complement(1706997..1708523) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110621 YP_002997479.1 CDS SDEG_1782 NC_012891.1 1708520 1709647 R similar to transcriptional regulator AraC family [Streptococcus equi subsp.zooepidemicus MGCS10565]; hypothetical protein complement(1708520..1709647) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111607 YP_002997480.1 CDS SDEG_1783 NC_012891.1 1709999 1710286 R similar to ISSdy1 transposase OrfB [Streptococcus agalactiae 2603V/R]; ISSdy1, transposase OrfB complement(1709999..1710286) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110622 YP_002997481.1 CDS SDEG_1784 NC_012891.1 1710378 1710779 R similar to ISSdy1 transposase OrfB [Streptococcus agalactiae 2603V/R]; ISSdy1, transposase OrfB complement(1710378..1710779) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110623 YP_002997482.1 CDS SDEG_1785 NC_012891.1 1710815 1711105 R similar to hypothetical protein gbs1310 [Streptococcus agalactiae NEM316]; hypothetical protein complement(1710815..1711105) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110624 YP_002997483.1 CDS SDEG_1786 NC_012891.1 1711366 1712169 R similar to transposase [Lactococcus lactis subsp. cremoris SK11]; transposase complement(1711366..1712169) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110625 YP_002997484.1 CDS SDEG_1787 NC_012891.1 1712344 1713336 D similar to esterase [Streptococcus pyogenes MGAS2096]; esterase 1712344..1713336 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110626 YP_002997485.1 CDS rbfA NC_012891.1 1713471 1713821 R associates with free 30S ribosomal subunits; essential for efficient processing of 16S rRNA; in Escherichia coli rbfA is induced by cold shock; ribosome-binding factor A complement(1713471..1713821) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110627 YP_002997486.1 CDS infB NC_012891.1 1714027 1716924 R Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; translation initiation factor IF-2 complement(1714027..1716924) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111350 YP_002997487.1 CDS SDEG_1790 NC_012891.1 1716944 1717246 R similar to LSU ribosomal protein L7AE [Streptococcus pyogenes MGAS10750]; hypothetical protein complement(1716944..1717246) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112052 YP_002997488.1 CDS SDEG_1791 NC_012891.1 1717239 1717538 R similar to hypothetical cytosolic protein [Streptococcus pyogenes MGAS10394]; hypothetical protein complement(1717239..1717538) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110628 YP_002997489.1 CDS nusA NC_012891.1 1717551 1718765 R modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination; transcription elongation factor NusA complement(1717551..1718765) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110629 YP_002997490.1 CDS SDEG_1793 NC_012891.1 1718851 1719300 R in Streptococcus pneumoniae this gene was found to be essential; structure determination of the Streptococcus protein shows that it is similar to a number of other proteins; hypothetical protein complement(1718851..1719300) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111725 YP_002997491.1 CDS trmB NC_012891.1 1719828 1720463 R tRNA (guanine-N(7)-)-methyltransferase; catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA by transferring the methyl residue from S-adenosyl-L-methionine; tRNA (guanine-N(7)-)-methyltransferase complement(1719828..1720463) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110631 YP_002997492.1 CDS SDEG_1796 NC_012891.1 1720463 1721254 R similar to phosphotransferase enzyme family protein [Streptococcus pyogenes str. Manfredo]; phosphotransferase complement(1720463..1721254) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111925 YP_002997493.1 CDS ecsB NC_012891.1 1721319 1722353 R similar to protein ecsB [Streptococcus pyogenes MGAS10270]; ABC transporter complement(1721319..1722353) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110632 YP_002997494.1 CDS ecsA NC_012891.1 1722356 1723081 R similar to ABC transporter (ATP-binding protein) [Streptococcus pyogenes M1 GAS]; ABC transporter ATP-binding protein complement(1722356..1723081) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111865 YP_002997495.1 CDS hit NC_012891.1 1723153 1723572 D similar to cell-cycle regulation histidine triad protein HIT [Streptococcus equi subsp. zooepidemicus MGCS10565]; cell-cycle regulation histidine triad protein HIT 1723153..1723572 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111864 YP_002997496.1 CDS SDEG_1800 NC_012891.1 1723569 1723898 D similar to COG0840, methyl-accepting chemotaxis protein [Streptococcus pyogenes M49 591]; COG0840: methyl-accepting chemotaxis protein 1723569..1723898 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112033 YP_002997497.1 CDS SDEG_1801 NC_012891.1 1724056 1725354 R similar to transcriptional regulator LytR family [Streptococcus pyogenes MGAS10394]; LytR family transcriptional regulator complement(1724056..1725354) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110633 YP_002997498.1 CDS SDEG_1802 NC_012891.1 1725336 1725857 R similar to acetyltransferase [Streptococcus pyogenes MGAS5005]; acetyltransferase complement(1725336..1725857) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110634 YP_002997499.1 CDS SDEG_1803 NC_012891.1 1725850 1726299 R similar to ATP/GTP hydrolase [Streptococcus pyogenes MGAS10394]; ATP/GTP hydrolase complement(1725850..1726299) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110635 YP_002997500.1 CDS SDEG_1804 NC_012891.1 1726470 1727930 R similar to guanine-hypoxanthine permease [Streptococcus equi subsp. zooepidemicus MGCS10565]; guanine-hypoxanthine permease complement(1726470..1727930) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110636 YP_002997501.1 CDS SDEG_1805 NC_012891.1 1728191 1729003 D similar to hydrolase HAD superfamily [Streptococcus pyogenes MGAS5005]; HAD superfamily hydrolase 1728191..1729003 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110637 YP_002997502.1 CDS manL NC_012891.1 1729356 1730348 D similar to PTS system mannose-specific IIAB component [Streptococcus pyogenes MGAS5005]; PTS system mannose-specific transporter subunit IIAB 1729356..1730348 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110638 YP_002997503.1 CDS manM NC_012891.1 1730434 1731243 D similar to PTS system mannose-specific IIC component [Streptococcus pyogenes MGAS5005]; PTS system mannose-specific transporter subunit IIC 1730434..1731243 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110928 YP_002997504.1 CDS manN NC_012891.1 1731260 1732171 D similar to PTS system mannose-specific IID component [Streptococcus pyogenes MGAS5005]; PTS system mannose-specific transporter subunit IID 1731260..1732171 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110929 YP_002997505.1 CDS manO NC_012891.1 1732285 1732659 D similar to hypothetical cytosolic protein [Streptococcus pyogenes MGAS5005]; hypothetical protein 1732285..1732659 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110930 YP_002997506.1 CDS SDEG_1810 NC_012891.1 1732766 1733833 R similar to hypothetical protein Sez 0419 [Streptococcus equi subsp. zooepidemicus MGCS10565]; hypothetical protein complement(1732766..1733833) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110931 YP_002997507.1 CDS serS NC_012891.1 1734256 1735533 D catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; seryl-tRNA synthetase 1734256..1735533 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110639 YP_002997508.1 CDS accD NC_012891.1 1735767 1736537 R catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer composed of two alpha (AccA) and two beta (AccD) subunits; one of the two catalytic subunits that can form the acetyl CoA carboxylase enzyme together with a carrier protein; these proteins present a shorter N-terminus; acetyl-CoA carboxylase subunit alpha complement(1735767..1736537) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110482 YP_002997509.1 CDS accA NC_012891.1 1736534 1737400 R catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer of AccA2D2 subunits; acetyl-CoA carboxylase subunit beta complement(1736534..1737400) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110852 YP_002997510.1 CDS accC NC_012891.1 1737409 1738773 R an AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism; acetyl-CoA carboxylase biotin carboxylase subunit complement(1737409..1738773) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110849 YP_002997511.1 CDS fabZ NC_012891.1 1738805 1739227 R similar to (3R)-hydroxymyristoyl ACP dehydratase [Streptococcus pyogenes MGAS10394]; (3R)-hydroxymyristoyl-ACP dehydratase complement(1738805..1739227) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110851 YP_002997512.1 CDS accB NC_012891.1 1739224 1739724 R composes the biotin carboxyl carrier protein subunit of the acetyl-CoA carboxylase complex, the enzyme that catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, which in turn controls the rate of fatty acid metabolism; acetyl-CoA carboxylase biotin carboxyl carrier protein subunit complement(1739224..1739724) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111880 YP_002997513.1 CDS fabF NC_012891.1 1739726 1740958 R FabF; beta-ketoacyl-ACP synthase II, KASII; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP; 3-oxoacyl-(acyl carrier protein) synthase II complement(1739726..1740958) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110850 YP_002997514.1 CDS fabG NC_012891.1 1740973 1741707 R catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis; 3-ketoacyl-ACP reductase complement(1740973..1741707) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111876 YP_002997515.1 CDS fabD NC_012891.1 1741719 1742645 R similar to acyl-carrier-protein S-malonyltransferase [Streptococcus pyogenes SSI-1]; ACP S-malonyltransferase complement(1741719..1742645) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111877 YP_002997516.1 CDS fabK NC_012891.1 1742664 1743635 R similar to enoyl-[acyl-carrier protein] reductase (NADH) [Streptococcus pyogenes MGAS5005]; enoyl-ACP reductase complement(1742664..1743635) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111875 YP_002997517.1 CDS acpP NC_012891.1 1743834 1744058 R carries the fatty acid chain in fatty acid biosynthesis; acyl carrier protein complement(1743834..1744058) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111879 YP_002997518.1 CDS fabH NC_012891.1 1744119 1745093 R FabH; beta-ketoacyl-acyl carrier protein synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs; 3-oxoacyl-ACP synthase complement(1744119..1745093) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112303 YP_002997519.1 CDS SDEG_1823 NC_012891.1 1745094 1745546 R similar to transcriptional regulator MarR family [Streptococcus pyogenes MGAS6180]; MarR family transcriptional regulator complement(1745094..1745546) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111878 YP_002997520.1 CDS phaB NC_012891.1 1745605 1746396 R Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; enoyl-CoA hydratase complement(1745605..1746396) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110640 YP_002997521.1 CDS dnaJ NC_012891.1 1746618 1747769 R chaperone Hsp40; co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion; chaperone protein DnaJ complement(1746618..1747769) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111289 YP_002997522.1 CDS thiJ-2 NC_012891.1 1747939 1748580 R similar to 4-methyl-5(beta-hydroxyethyl)-thiazole monophosphate synthesis protein [Streptococcus gordonii str. Challis substr. CH1]; 4-methyl-5(beta-hydroxyethyl)-thiazole monophosphate synthesis protein complement(1747939..1748580) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111848 YP_002997523.1 CDS dnaK NC_012891.1 1748848 1750674 R heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria; molecular chaperone DnaK complement(1748848..1750674) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110518 YP_002997524.1 CDS SDEG_1828 NC_012891.1 1750472 1750693 D similar to hypothetical protein FN0115 [Fusobacterium nucleatum subsp. nucleatum ATCC 25586]; hypothetical protein 1750472..1750693 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111849 YP_002997525.1 CDS grpE NC_012891.1 1750792 1751334 R with DnaK and DnaJ acts in response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins; may act as a thermosensor; heat shock protein GrpE complement(1750792..1751334) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110641 YP_002997526.1 CDS hrcA NC_012891.1 1751376 1752410 R Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons; heat-inducible transcription repressor complement(1751376..1752410) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112021 YP_002997527.1 CDS SDEG_1831 NC_012891.1 1752545 1753114 R similar to N-acetyl-muramidase [Streptococcus pyogenes MGAS8232]; N-acetyl-muramidase complement(1752545..1753114) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112037 YP_002997528.1 CDS SDEG_1832 NC_012891.1 1753111 1753854 R similar to DD-carboxypeptidase [Streptococcus pyogenes MGAS8232]; D,D-carboxypeptidase complement(1753111..1753854) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110642 YP_002997529.1 CDS SDEG_1833 NC_012891.1 1753844 1754563 R similar to phosphoglycerate mutase [Streptococcus pyogenes MGAS10394]; phosphoglycerate mutase complement(1753844..1754563) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110643 YP_002997530.1 CDS SDEG_1834 NC_012891.1 1754857 1755099 R similar to hypothetical membrane spanning protein [Streptococcus pyogenes MGAS10394]; hypothetical protein complement(1754857..1755099) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110644 YP_002997531.1 CDS SDEG_1835 NC_012891.1 1755164 1756105 R similar to drug/metabolite transporter (DMT) superfamily protein [Streptococcus equi subsp. zooepidemicus MGCS10565]; drug/metabolite transporter superfamily protein complement(1755164..1756105) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110645 YP_002997532.1 CDS SDEG_1836 NC_012891.1 1756271 1757404 R similar to transposase [Streptococcus pyogenes MGAS5005]; transposase complement(1756271..1757404) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110646 YP_002997533.1 CDS gatB NC_012891.1 1757654 1759093 R allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; aspartyl/glutamyl-tRNA amidotransferase subunit B complement(1757654..1759093) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110647 YP_002997534.1 CDS gatA NC_012891.1 1759093 1760559 R allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; aspartyl/glutamyl-tRNA amidotransferase subunit A complement(1759093..1760559) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111987 YP_002997535.1 CDS gatC NC_012891.1 1760559 1760873 R allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; some Mycoplasma proteins contain an N-terminal fusion to an unknown domain; aspartyl/glutamyl-tRNA amidotransferase subunit C complement(1760559..1760873) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111986 YP_002997536.1 CDS SDEG_1840 NC_012891.1 1761093 1763738 R catalyzes the formation of phosphoenolpyruvate from pyruvate; pyruvate phosphate dikinase complement(1761093..1763738) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111988 YP_002997537.1 CDS SDEG_1841 NC_012891.1 1763752 1764591 R similar to hypothetical protein SAG1671 [Streptococcus agalactiae 2603V/R]; hypothetical protein complement(1763752..1764591) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110648 YP_002997538.1 CDS SDEG_1842 NC_012891.1 1764612 1765115 R similar to hypothetical protein [Streptococcus agalactiae 2603V/R]; hypothetical protein complement(1764612..1765115) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110649 YP_002997539.1 CDS SDEG_1843 NC_012891.1 1765436 1765735 R similar to hypothetical protein STRINF 01222 [Streptococcus infantarius subsp. infantarius ATCC BAA-102]; hypothetical protein complement(1765436..1765735) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110650 YP_002997540.1 CDS SDEG_1844 NC_012891.1 1765728 1767380 R similar to hypothetical protein STRINF 01221 [Streptococcus infantarius subsp. infantarius ATCC BAA-102]; hypothetical protein complement(1765728..1767380) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110651 YP_002997541.1 CDS SDEG_1845 NC_012891.1 1767398 1767736 R similar to rhodanese-like [Enterococcus faecium DO]; rhodanese-like protein complement(1767398..1767736) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110652 YP_002997542.1 CDS SDEG_1846 NC_012891.1 1767950 1768210 D similar to hypothetical protein STRINF 01219 [Streptococcus infantarius subsp. infantarius ATCC BAA-102]; hypothetical protein 1767950..1768210 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110653 YP_002997543.1 CDS SDEG_1847 NC_012891.1 1768277 1768825 R nicotinamidase; pyrazinamidase complement(1768277..1768825) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110654 YP_002997544.1 CDS codY NC_012891.1 1768966 1769748 R CodY; DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase (By similarity). It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor; transcriptional repressor CodY complement(1768966..1769748) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110655 YP_002997545.1 CDS alaT NC_012891.1 1770013 1771227 R broad specificity; family IV; in Corynebacterium glutamicum this protein can use glutamate, 2-aminobutyrate, and aspartate as amino donors and pyruvate as the acceptor; aminotransferase AlaT complement(1770013..1771227) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111631 YP_002997546.1 CDS SDEG_1850 NC_012891.1 1771564 1772016 D similar to universal stress protein family [Streptococcus pyogenes MGAS6180]; universal stress protein family 1771564..1772016 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112320 YP_002997547.1 CDS SDEG_1851 NC_012891.1 1772179 1773567 R similar to hydrolase (HAD superfamily) [Streptococcus equi subsp. zooepidemicus MGCS10565]; HAD superfamily hydrolase complement(1772179..1773567) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110656 YP_002997548.1 CDS asnB NC_012891.1 1773640 1774605 D similar to L-asparaginase [Streptococcus pyogenes M1 GAS]; L-asparaginase 1773640..1774605 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110657 YP_002997549.1 CDS SDEG_1853 NC_012891.1 1774655 1775572 R similar to oxidoreductase aldo/keto reductase family [Streptococcus agalactiae 2603V/R]; oxidoreductase, aldo/keto reductase family complement(1774655..1775572) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112349 YP_002997550.1 CDS recG NC_012891.1 1775769 1777799 R similar to ATP-dependent DNA helicase RecG [Streptococcus equi subsp. zooepidemicus MGCS10565]; ATP-dependent DNA helicase RecG complement(1775769..1777799) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110658 YP_002997551.1 CDS cbiO NC_012891.1 1777885 1779360 R similar to Cobalt transport ATP-binding protein cbiO [Streptococcus pyogenes MGAS2096]; cobalt transport ATP-binding protein cbiO complement(1777885..1779360) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111034 YP_002997552.1 CDS cbiQ NC_012891.1 1779276 1779956 R similar to cobalt transport protein cbiQ [Streptococcus pyogenes MGAS5005]; cobalt transport protein cbiQ complement(1779276..1779956) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111605 YP_002997553.1 CDS SDEG_1857 NC_012891.1 1779953 1780546 R similar to hypothetical protein SpyM3 1555 [Streptococcus pyogenes MGAS315]; hypothetical protein complement(1779953..1780546) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111606 YP_002997554.1 CDS SDEG_1858 NC_012891.1 1780543 1782246 R similar to ABC transporter ATP-binding protein [Streptococcus pyogenes MGAS10270]; ABC transporter ATP-binding protein complement(1780543..1782246) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110659 YP_002997555.1 CDS SDEG_1859 NC_012891.1 1782206 1783969 R similar to ABC transporter (ATP-binding protein) [Streptococcus pyogenes MGAS8232]; ABC transporter ATP-binding protein complement(1782206..1783969) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110660 YP_002997556.1 CDS fhuC NC_012891.1 1783982 1784803 R similar to ferrichrome transport ATP-binding protein [Streptococcus pyogenes MGAS6180]; ferrichrome transport ATP-binding protein complement(1783982..1784803) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110661 YP_002997557.1 CDS fhuB NC_012891.1 1784800 1785822 R similar to ferrichrome transport system permease protein [Streptococcus pyogenes MGAS10394]; ferrichrome transport system permease complement(1784800..1785822) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111895 YP_002997558.1 CDS SDEG_1862 NC_012891.1 1785824 1786747 R similar to ferrichrome-binding protein [Streptococcus pyogenes MGAS10750]; ferrichrome-binding protein complement(1785824..1786747) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111894 YP_002997559.1 CDS shp NC_012891.1 1786692 1787573 R similar to hypothetical protein MGAS10270 Spy1597 [Streptococcus pyogenes MGAS10270]; hypothetical protein complement(1786692..1787573) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110662 YP_002997560.1 CDS SDEG_1864 NC_012891.1 1787788 1791525 R similar to Fe3+-siderophore transport protein [Streptococcus pyogenes MGAS10750]; Fe3+-siderophore transport protein complement(1787788..1791525) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110483 YP_002997561.1 CDS isp2 NC_012891.1 1791814 1793289 R similar to immunogenic secreted protein [Streptococcus pyogenes MGAS6180]; immunogenic secreted protein complement(1791814..1793289) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110663 YP_002997562.1 CDS alr NC_012891.1 1793379 1794479 R converts L-alanine to D-alanine which is used in cell wall biosynthesis; binds one pyridoxal phosphate per monomer; forms a homodimer; alanine racemase complement(1793379..1794479) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110874 YP_002997563.1 CDS acpS NC_012891.1 1794476 1794832 R Catalyzes the formation of holo-ACP, which mediates the essential transfer of acyl fatty acid intermediates during the biosynthesis of fatty acids and lipids; 4'-phosphopantetheinyl transferase complement(1794476..1794832) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112305 YP_002997564.1 CDS secA NC_012891.1 1794953 1797481 R functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond SecA1; SecA2 is not essential and seems to play a role in secretion of a subset of proteins; preprotein translocase subunit SecA complement(1794953..1797481) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112306 YP_002997565.1 CDS manA NC_012891.1 1797617 1798570 R similar to mannose-6-phosphate isomerase [Streptococcus pyogenes str. Manfredo]; mannose-6-phosphate isomerase complement(1797617..1798570) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110477 YP_002997566.1 CDS scrK NC_012891.1 1798664 1799548 R similar to fructokinase [Streptococcus pyogenes MGAS10750]; fructokinase complement(1798664..1799548) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110927 YP_002997567.1 CDS scrA NC_012891.1 1799734 1801617 R similar to PTS system sucrose-specific IIABC component [Streptococcus pyogenes MGAS5005]; PTS system sucrose-specific transporter subunit IIABC complement(1799734..1801617) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110471 YP_002997568.1 CDS scrB NC_012891.1 1801860 1803299 D similar to sucrose-6-phosphate hydrolase [Streptococcus pyogenes MGAS10394]; sucrose-6-phosphate hydrolase 1801860..1803299 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110469 YP_002997569.1 CDS scrR NC_012891.1 1803304 1804269 D similar to sucrose operon repressor [Streptococcus pyogenes MGAS5005]; sucrose operon repressor 1803304..1804269 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110470 YP_002997570.1 CDS nusB NC_012891.1 1804462 1804929 R Regulates rRNA biosynthesis by transcriptional antitermination; transcription antitermination protein NusB complement(1804462..1804929) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110472 YP_002997571.1 CDS SDEG_1875 NC_012891.1 1804904 1805293 R similar to general stress protein Gls24 family [Streptococcus pyogenes MGAS6180]; Gls24 family general stress protein complement(1804904..1805293) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111726 YP_002997572.1 CDS efp NC_012891.1 1805339 1805896 R Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA; elongation factor P complement(1805339..1805896) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110664 YP_002997573.1 CDS comEB NC_012891.1 1805984 1806451 R similar to ComE operon protein 2 [Streptococcus pyogenes MGAS6180]; ComE operon protein 2 complement(1805984..1806451) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111866 YP_002997574.1 CDS SDEG_1878 NC_012891.1 1806485 1807597 R similar to Xaa-Pro dipeptidase [Streptococcus pyogenes MGAS6180]; Xaa-Pro dipeptidase complement(1806485..1807597) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111633 YP_002997575.1 CDS uvrA NC_012891.1 1807673 1810531 R The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate; excinuclease ABC subunit A complement(1807673..1810531) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110665 YP_002997576.1 CDS corA NC_012891.1 1810704 1811648 D similar to magnesium and cobalt transport protein corA [Streptococcus pyogenes MGAS10394]; magnesium and cobalt transport protein corA 1810704..1811648 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111944 YP_002997577.1 CDS SDEG_1881 NC_012891.1 1811780 1812436 D similar to hypothetical membrane spanning protein [Streptococcus pyogenes MGAS5005]; hypothetical protein 1811780..1812436 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111642 YP_002997578.1 CDS rpsR NC_012891.1 1812567 1812806 R binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit; 30S ribosomal protein S18 complement(1812567..1812806) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110666 YP_002997579.1 CDS ssb2 NC_012891.1 1812971 1813462 R binds to single stranded DNA and may facilitate the binding and interaction of other proteins to DNA; single-stranded DNA-binding protein complement(1812971..1813462) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111109 YP_002997580.1 CDS rpsF NC_012891.1 1813484 1813774 R binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21; 30S ribosomal protein S6 complement(1813484..1813774) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110505 YP_002997581.1 CDS SDEG_1885 NC_012891.1 1814733 1814969 R similar to hypothetical protein SpyM50294 [Streptococcus pyogenes str. Manfredo]; hypothetical protein complement(1814733..1814969) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111097 YP_002997582.1 CDS mutY NC_012891.1 1815192 1816358 D similar to A/G-specific adenine glycosylase [Streptococcus equi subsp. zooepidemicus MGCS10565]; A/G-specific adenine glycosylase 1815192..1816358 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110667 YP_002997583.1 CDS trxA NC_012891.1 1816409 1816723 R similar to thioredoxin [Streptococcus equi subsp. zooepidemicus MGCS10565]; thioredoxin complement(1816409..1816723) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111698 YP_002997584.1 CDS ykgC NC_012891.1 1816949 1818268 D Involved in disulfide oxidoreductase activity and electron transport; pyridine nucleotide-disulfide oxidoreductase 1816949..1818268 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111933 YP_002997585.1 CDS mutSB NC_012891.1 1818361 1820697 R similar to recombination inhibitory protein MutS2 [Streptococcus equi subsp. zooepidemicus MGCS10565]; recombination inhibitory protein MutS2 complement(1818361..1820697) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111966 YP_002997586.1 CDS SDEG_1890 NC_012891.1 1820853 1821398 R similar to colicin V production protein [Streptococcus pyogenes MGAS5005]; colicin V production protein complement(1820853..1821398) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111696 YP_002997587.1 CDS SDEG_1891 NC_012891.1 1821401 1821709 R similar to hypothetical protein SpyM50287 [Streptococcus pyogenes str. Manfredo]; hypothetical protein complement(1821401..1821709) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110668 YP_002997588.1 CDS SDEG_1892 NC_012891.1 1821866 1822765 D An endonuclease that specifically degrades the RNA strand of RNA-DNA hybrids; ribonuclease HIII 1821866..1822765 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110669 YP_002997589.1 CDS spi NC_012891.1 1822787 1823380 D similar to signal peptidase I [Streptococcus pyogenes MGAS10394]; signal peptidase I 1822787..1823380 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110670 YP_002997590.1 CDS recD NC_012891.1 1823440 1825893 D similar to exodeoxyribonuclease V alpha chain [Streptococcus pyogenes MGAS5005]; exodeoxyribonuclease V subunit alpha 1823440..1825893 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110497 YP_002997591.1 CDS SDEG_1895 NC_012891.1 1825984 1826472 D similar to hypothetical protein SPs0273 [Streptococcus pyogenes SSI-1]; hypothetical protein 1825984..1826472 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111032 YP_002997592.1 CDS dinB NC_012891.1 1826561 1827658 R involved in translesion DNA polymerization with beta clamp of polymerase III; belongs to Y family of polymerases; does not contain proofreading function; DNA polymerase IV complement(1826561..1827658) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110671 YP_002997593.1 CDS pfl NC_012891.1 1827867 1830194 D similar to formate acetyltransferase [Streptococcus pyogenes MGAS5005]; formate acetyltransferase 1827867..1830194 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111672 YP_002997594.1 CDS SDEG_1898 NC_012891.1 1830299 1830751 D similar to acetyltransferase GNAT family [Streptococcus thermophilus LMD-9]; GNAT family acetyltransferase 1830299..1830751 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111284 YP_002997595.1 CDS SDEG_1899 NC_012891.1 1830875 1832782 R similar to alpha amylase catalytic region [Chloroflexus aurantiacus J-10-fl]; alpha amylase complement(1830875..1832782) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110672 YP_002997596.1 CDS SDEG_1900 NC_012891.1 1832869 1834440 R similar to ABC-type sugar transport system periplasmic component [Lactococcus lactis subsp. cremoris SK11]; sugar ABC transporter substrate-binding protein complement(1832869..1834440) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110673 YP_002997597.1 CDS SDEG_1901 NC_012891.1 1834507 1835160 R similar to hypothetical protein llmg 1837 [Lactococcus lactis subsp. cremoris MG1363]; hypothetical protein complement(1834507..1835160) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110674 YP_002997598.1 CDS SDEG_1902 NC_012891.1 1835172 1836071 R similar to ABC-type sugar transport system permease component [Lactococcus lactis subsp. cremoris SK11]; sugar ABC transporter permease complement(1835172..1836071) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110675 YP_002997599.1 CDS SDEG_1903 NC_012891.1 1836084 1837022 R similar to ABC-type polysaccharide transport system permease component [Lactococcus lactis subsp. cremoris SK11]; polysaccharide ABC transporter permease complement(1836084..1837022) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110676 YP_002997600.1 CDS SDEG_1904 NC_012891.1 1837629 1838660 D similar to regulatory protein LacI [Clostridium beijerinckii NCIMB 8052]; regulatory protein, LacI 1837629..1838660 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110677 YP_002997601.1 CDS SDEG_1905 NC_012891.1 1838772 1839707 R similar to beta-lactamase family protein [Streptococcus pyogenes MGAS2096]; beta-lactamase complement(1838772..1839707) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110678 YP_002997602.1 CDS SDEG_1906 NC_012891.1 1839704 1840456 R similar to hypothetical cytosolic protein [Streptococcus pyogenes MGAS10750]; hypothetical protein complement(1839704..1840456) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110679 YP_002997603.1 CDS SDEG_1907 NC_012891.1 1840682 1841623 D similar to hypothetical membrane spanning protein [Streptococcus pyogenes MGAS2096]; hypothetical protein 1840682..1841623 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110680 YP_002997604.1 CDS SDEG_1908 NC_012891.1 1841727 1842575 R similar to hypothetical protein SSU98 0262 [Streptococcus suis 98HAH33]; hypothetical protein complement(1841727..1842575) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110681 YP_002997605.1 CDS pepX NC_012891.1 1842702 1844984 D catalyzes the removal of N-terminal dipeptides when proline is the penultimate residue; x-prolyl-dipeptidyl aminopeptidase 1842702..1844984 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110682 YP_002997606.1 CDS SDEG_1910 NC_012891.1 1845057 1845449 R similar to hypothetical protein Sez 0318 [Streptococcus equi subsp. zooepidemicus MGCS10565]; hypothetical protein complement(1845057..1845449) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111281 YP_002997607.1 CDS SDEG_1911 NC_012891.1 1845619 1845840 R similar to hypothetical protein spyM18 1923 [Streptococcus pyogenes MGAS8232]; hypothetical protein complement(1845619..1845840) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110683 YP_002997608.1 CDS SDEG_1912 NC_012891.1 1846010 1846384 D similar to transcriptional regulator [Streptococcus pyogenes MGAS6180]; transcriptional regulator 1846010..1846384 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110684 YP_002997609.1 CDS SDEG_1913 NC_012891.1 1846577 1846876 D similar to hypothetical cytosolic protein [Streptococcus pyogenes MGAS2096]; hypothetical protein 1846577..1846876 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110685 YP_002997610.1 CDS SDEG_1914 NC_012891.1 1846933 1847670 R similar to transcriptional regulator MerR family [Streptococcus pyogenes MGAS5005]; MerR family transcriptional regulator complement(1846933..1847670) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110686 YP_002997611.1 CDS dnaQ NC_012891.1 1847823 1848422 R 3'-5' exonuclease of DNA polymerase III; DNA polymerase III subunit epsilon complement(1847823..1848422) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110687 YP_002997612.1 CDS SDEG_1916 NC_012891.1 1848458 1849009 R similar to DNA-binding protein [Streptococcus pyogenes str. Manfredo]; DNA-binding protein complement(1848458..1849009) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111851 YP_002997613.1 CDS paaB NC_012891.1 1849363 1849596 D similar to transposase [Streptococcus criceti]; transposase 1849363..1849596 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110688 YP_002997614.1 CDS SDEG_1918 NC_012891.1 1849647 1850822 D similar to hypothetical protein SPs0257 [Streptococcus pyogenes SSI-1]; hypothetical protein 1849647..1850822 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111747 YP_002997615.1 CDS SDEG_1919 NC_012891.1 1850882 1851136 R similar to hypothetical protein [Streptococcus thermophilus]; hypothetical protein complement(1850882..1851136) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110689 YP_002997616.1 CDS rpsN NC_012891.1 1851477 1851746 D located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group do not appear to have the zinc-binding motif; 30S ribosomal protein S14 1851477..1851746 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110690 YP_002997617.1 CDS SDEG_1921 NC_012891.1 1852076 1853092 R in most organisms, only the N-terminal domain is present in a single polypeptide; in some archaea this domain is fused to a kinase domain; this gene is essential for growth in Escherichia coli and Bacillus subtilis; the secreted glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins; the Pyrococcus structure shows DNA-binding properties, iron-binding, ATP-binding, and AP endonuclease activity; DNA-binding/iron metalloprotein/AP endonuclease complement(1852076..1853092) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111106 YP_002997618.1 CDS SDEG_1922 NC_012891.1 1853082 1853537 R similar to ribosomal-protein-alanine acetyltransferase [Streptococcus pyogenes MGAS6180]; ribosomal-protein-alanine acetyltransferase complement(1853082..1853537) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112460 YP_002997619.1 CDS SDEG_1923 NC_012891.1 1853509 1854240 R similar to non-proteolytic protein peptidase family M22 [Streptococcus pyogenes MGAS10270]; non-proteolytic protein, peptidase family M22 complement(1853509..1854240) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112461 YP_002997620.1 CDS SDEG_1924 NC_012891.1 1854493 1854723 D similar to hypothetical protein SpyM50257 [Streptococcus pyogenes str. Manfredo]; hypothetical protein 1854493..1854723 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112462 YP_002997621.1 CDS SDEG_1925 NC_012891.1 1854725 1856407 D similar to Zn-dependent hydrolase [Streptococcus pyogenes MGAS10394]; Zn-dependent hydrolase 1854725..1856407 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112463 YP_002997622.1 CDS oppF NC_012891.1 1856586 1857518 R similar to oligopeptide transport ATP-binding protein OppF [Streptococcus equi subsp. zooepidemicus MGCS10565]; oligopeptide transport ATP-binding protein complement(1856586..1857518) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112464 YP_002997623.1 CDS oppD NC_012891.1 1857511 1858563 R similar to oligopeptide transport ATP-binding protein OppD [Streptococcus equi subsp. zooepidemicus MGCS10565]; oligopeptide transport ATP-binding protein complement(1857511..1858563) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111742 YP_002997624.1 CDS oppC NC_012891.1 1858575 1859606 R similar to oligopeptide transport system permease protein OppC [Streptococcus equi subsp. zooepidemicus MGCS10565]; oligopeptide transport system permease complement(1858575..1859606) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111740 YP_002997625.1 CDS oppB NC_012891.1 1859616 1860530 R similar to oligopeptide transport system permease protein OppB [Streptococcus equi subsp. zooepidemicus MGCS10565]; oligopeptide transport system permease complement(1859616..1860530) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111738 YP_002997626.1 CDS oppA NC_012891.1 1860798 1862453 R similar to oligopeptide-binding protein OppA precursor [Streptococcus equi subsp. zooepidemicus MGCS10565]; oligopeptide-binding protein complement(1860798..1862453) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111736 YP_002997627.1 CDS glnA NC_012891.1 1862686 1864032 R similar to glutamine synthetase [Streptococcus pyogenes str. Manfredo]; glutamine synthetase complement(1862686..1864032) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111734 YP_002997628.1 CDS SDEG_1932 NC_012891.1 1864070 1864441 R similar to transcriptional regulator MerR family [Streptococcus pyogenes MGAS10394]; MerR family transcriptional regulator complement(1864070..1864441) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112002 YP_002997629.1 CDS SDEG_1933 NC_012891.1 1864518 1865039 R similar to hypothetical protein SpyM50253 [Streptococcus pyogenes str. Manfredo]; hypothetical protein complement(1864518..1865039) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112465 YP_002997630.1 CDS pgk NC_012891.1 1865536 1866732 R Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway; phosphoglycerate kinase complement(1865536..1866732) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112466 YP_002997631.1 CDS lppC NC_012891.1 1866916 1867773 R similar to acid phosphatase [Streptococcus dysgalactiae subsp. equisimilis]; acid phosphatase complement(1866916..1867773) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111286 YP_002997632.1 CDS gapA NC_012891.1 1867957 1868967 R similar to glyceraldehyde-3-phosphate dehydrogenaseplasmin receptor [Streptococcus pyogenes str. Manfredo]; glyceraldehyde-3-phosphate dehydrogenase complement(1867957..1868967) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110908 YP_002997633.1 CDS fus NC_012891.1 1869307 1871385 R EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene; elongation factor G complement(1869307..1871385) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111984 YP_002997634.1 CDS rpsG NC_012891.1 1871803 1872273 R binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit; 30S ribosomal protein S7 complement(1871803..1872273) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111981 YP_002997635.1 CDS rpsL NC_012891.1 1872294 1872707 R interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance; 30S ribosomal protein S12 complement(1872294..1872707) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111098 YP_002997636.1 CDS prgA NC_012891.1 1872968 1875589 R similar to surface exclusion protein [Streptococcus pyogenes MGAS10750]; surface exclusion protein complement(1872968..1875589) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111103 YP_002997637.1 CDS purR NC_012891.1 1875580 1876419 R similar to purine operon repressor [Streptococcus pyogenes MGAS10394]; pur operon repressor complement(1875580..1876419) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111308 YP_002997638.1 CDS cbf NC_012891.1 1876519 1877457 R similar to CMP-binding factor [Streptococcus pyogenes MGAS5005]; CMP-binding factor complement(1876519..1877457) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111336 YP_002997639.1 CDS SDEG_1943 NC_012891.1 1877447 1878718 R similar to RmuC family protein [Streptococcus pyogenes MGAS10394]; RmuC family DNA recombination protein complement(1877447..1878718) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111604 YP_002997640.1 CDS SDEG_1944 NC_012891.1 1878720 1879352 R similar to thiamine pyrophosphokinase [Streptococcus pyogenes MGAS5005]; thiamine pyrophosphokinase complement(1878720..1879352) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112467 YP_002997641.1 CDS rpe NC_012891.1 1879345 1880007 R catalyzes the interconversion of D-ribulose 5-phosphate to xylulose 5-phosphate; ribulose-phosphate 3-epimerase complement(1879345..1880007) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112468 YP_002997642.1 CDS SDEG_1946 NC_012891.1 1880017 1880889 R EngC; RsgA; CpgA; circularly permuted GTPase; ribosome small subunit-dependent GTPase A; has the pattern G4-G1-G3 as opposed to other GTPases; interacts strongly with 30S ribosome which stimulates GTPase activity; ribosome-associated GTPase complement(1880017..1880889) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111056 YP_002997643.1 CDS ksgA NC_012891.1 1881312 1882208 R catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin; dimethyladenosine transferase complement(1881312..1882208) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112469 YP_002997644.1 CDS SDEG_1948 NC_012891.1 1882298 1882909 R similar to ribonuclease M5 [Streptococcus pyogenes MGAS6180]; ribonuclease M5 complement(1882298..1882909) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110877 YP_002997645.1 CDS tatD NC_012891.1 1882860 1883651 R similar to TatD related DNase [Streptococcus pyogenes str. Manfredo]; TatD related DNase complement(1882860..1883651) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112470 YP_002997646.1 CDS SDEG_1950 NC_012891.1 1883793 1884269 D similar to hydrolase [Staphylococcus aureus RF122]; hydrolase 1883793..1884269 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110513 YP_002997647.1 CDS SDEG_1951 NC_012891.1 1884393 1885223 D similar to transcriptional regulator RpiR family [Streptococcus pyogenes MGAS5005]; RpiR family transcriptional regulator 1884393..1885223 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112471 YP_002997648.1 CDS SDEG_1952 NC_012891.1 1885339 1886226 R similar to N-acetylmannosamine kinase [Streptococcus pyogenes MGAS10394]; N-acetylmannosamine kinase complement(1885339..1886226) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112472 YP_002997649.1 CDS nanH NC_012891.1 1886243 1887160 R similar to N-acetylneuraminate lyase [Streptococcus pyogenes MGAS5005]; N-acetylneuraminate lyase complement(1886243..1887160) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112473 YP_002997650.1 CDS SDEG_1954 NC_012891.1 1887172 1887834 R similar to hypothetical membrane spanning protein [Streptococcus pyogenes MGAS5005]; hypothetical protein complement(1887172..1887834) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111708 YP_002997651.1 CDS SDEG_1955 NC_012891.1 1887878 1888333 R similar to hypothetical protein spyM18 0238 [Streptococcus pyogenes MGAS8232]; hypothetical protein complement(1887878..1888333) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112474 YP_002997652.1 CDS SDEG_1956 NC_012891.1 1888353 1889183 R similar to N-acetylneuraminate transport system permease protein [Streptococcus pyogenes MGAS6180]; N-acetylneuraminate transport system permease complement(1888353..1889183) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112475 YP_002997653.1 CDS SDEG_1957 NC_012891.1 1889196 1890185 R similar to N-acetylneuraminate transport system permease protein [Streptococcus pyogenes MGAS6180]; N-acetylneuraminate transport system permease complement(1889196..1890185) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112476 YP_002997654.1 CDS SDEG_1958 NC_012891.1 1890186 1891505 R similar to N-acetylneuraminate-binding protein [Streptococcus pyogenes MGAS5005]; N-acetylneuraminate-binding protein complement(1890186..1891505) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112477 YP_002997655.1 CDS SDEG_1959 NC_012891.1 1891554 1892258 R Converts N-acetylmannosamine-6-phosphate to N-acetylglucosamine-6-phosphate; N-acetylmannosamine-6-phosphate 2-epimerase complement(1891554..1892258) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112478 YP_002997656.1 CDS rpmH NC_012891.1 1892589 1892723 R in Escherichia coli transcription of this gene is enhanced by polyamines; 50S ribosomal protein L34 complement(1892589..1892723) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112479 YP_002997657.1 CDS SDEG_1961 NC_012891.1 1893036 1893950 R similar to jag protein [Streptococcus pyogenes MGAS5005]; jag protein complement(1893036..1893950) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111086 YP_002997658.1 CDS SDEG_1962 NC_012891.1 1893962 1894777 R similar to membrane protein oxaA 1 precursor [Streptococcus pyogenes NZ131]; membrane protein OxaA complement(1893962..1894777) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112480 YP_002997659.1 CDS rnpA NC_012891.1 1894755 1895114 R protein component of RNaseP which catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'terminus; this enzyme also cleaves other RNA substrates; ribonuclease P complement(1894755..1895114) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112481 YP_002997660.1 CDS fasA NC_012891.1 1895656 1896396 R similar to response regulator FasA [Streptococcus dysgalactiae subsp. equisimilis]; response regulator complement(1895656..1896396) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111052 YP_002997661.1 CDS fasC NC_012891.1 1896400 1897683 R similar to sensory transduction protein kinase [Streptococcus pyogenes MGAS6180]; sensory transduction protein kinase complement(1896400..1897683) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111882 YP_002997662.1 CDS fasB NC_012891.1 1897684 1899027 R similar to FasB [Streptococcus pyogenes MGAS10394]; sensory transduction protein kinase complement(1897684..1899027) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111884 YP_002997663.1 CDS gltX NC_012891.1 1899642 1901090 R Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation; glutamyl-tRNA synthetase complement(1899642..1901090) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111883 YP_002997664.1 CDS SDEG_1968 NC_012891.1 1901223 1902491 R similar to lantibiotic efflux protein [Streptococcus suis 05ZYH33]; lantibiotic efflux protein complement(1901223..1902491) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112011 YP_002997665.1 CDS SDEG_1969 NC_012891.1 1902586 1903287 R similar to hypothetical protein SSA 1981 [Streptococcus sanguinis SK36]; hypothetical protein complement(1902586..1903287) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112482 YP_002997666.1 CDS SDEG_1970 NC_012891.1 1903291 1903737 R similar to response regulator of the LytR/AlgR family [Streptococcus suis 98HAH33]; LytR/AlgR family response regulator complement(1903291..1903737) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112483 YP_002997667.1 CDS SDEG_1971 NC_012891.1 1903966 1904682 R similar to HTH DNA-binding protein [Streptococcus equi subsp. zooepidemicus MGCS10565]; HTH DNA-binding protein complement(1903966..1904682) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112484 YP_002997668.1 CDS SDEG_1972 NC_012891.1 1904818 1905312 R similar to carbonic anhydrase [Streptococcus pyogenes MGAS10394]; carbonic anhydrase complement(1904818..1905312) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112485 YP_002997669.1 CDS radA NC_012891.1 1905502 1906764 R similar to DNA repair protein [Streptococcus pyogenes str. Manfredo]; DNA repair protein complement(1905502..1906764) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112486 YP_002997670.1 CDS dut NC_012891.1 1906946 1907392 R catalyzes the formation of dUMP from dUTP; deoxyuridine 5'-triphosphate nucleotidohydrolase complement(1906946..1907392) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111348 YP_002997671.1 CDS SDEG_1975 NC_012891.1 1907500 1908267 R similar to hypothetical cytosolic protein [Streptococcus pyogenes MGAS6180]; hypothetical protein complement(1907500..1908267) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111861 YP_002997672.1 CDS SDEG_1976 NC_012891.1 1908386 1910170 R similar to multidrug resistance ABC transporter ATP-binding and permease protein [Streptococcus pyogenes MGAS10394]; multidrug resistance ABC transporter ATP-bindingprotein/permease complement(1908386..1910170) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112487 YP_002997673.1 CDS SDEG_1977 NC_012891.1 1910170 1911879 R similar to ABC transporter ATP-binding protein [Streptococcus pyogenes M1 GAS]; ABC transporter ATP-binding protein complement(1910170..1911879) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112488 YP_002997674.1 CDS SDEG_1978 NC_012891.1 1911872 1912321 R similar to hypothetical protein spyM18 0213 [Streptococcus pyogenes MGAS8232]; hypothetical protein complement(1911872..1912321) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112489 YP_002997675.1 CDS gpsA NC_012891.1 1912522 1913538 D catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate; NAD(P)H-dependent glycerol-3-phosphate dehydrogenase 1912522..1913538 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112490 YP_002997676.1 CDS hasC NC_012891.1 1913570 1914472 D similar to UDP-glucose pyrophosphorylase [Streptococcus pyogenes MGAS8232]; UDP-glucose pyrophosphorylase 1913570..1914472 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112017 YP_002997677.1 CDS SDEG_1981 NC_012891.1 1914653 1915279 D similar to integral membrane protein [Lactobacillus plantarum WCFS1]; integral membrane protein 1914653..1915279 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112027 YP_002997678.1 CDS SDEG_1982 NC_012891.1 1915456 1916130 R similar to integral membrane protein (rhomboid family) [Streptococcus pyogenes MGAS10394]; integral membrane protein complement(1915456..1916130) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112491 YP_002997679.1 CDS SDEG_1983 NC_012891.1 1916127 1916654 R similar to 5-formyltetrahydrofolate cyclo-ligase family protein [Streptococcus agalactiae 2603V/R]; 5-formyltetrahydrofolate cyclo-ligase complement(1916127..1916654) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112492 YP_002997680.1 CDS fnz NC_012891.1 1917195 1918778 R similar to fibronectin-binding protein [Streptococcus equi subsp. zooepidemicus]; fibronectin-binding protein complement(1917195..1918778) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112493 YP_002997681.1 CDS rofA NC_012891.1 1919210 1920715 D similar to transcriptional regulator [Streptococcus pyogenes MGAS10270]; transcriptional regulator 1919210..1920715 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111901 YP_002997682.1 CDS SDEG_1986 NC_012891.1 1920829 1921953 R similar to hypothetical protein llmg 0526 [Lactococcus lactis subsp. cremoris MG1363]; hypothetical protein complement(1920829..1921953) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111054 YP_002997683.1 CDS SDEG_1987 NC_012891.1 1921989 1922486 R similar to hypothetical protein BIFDEN 02311 [Bifidobacterium dentium ATCC 27678]; hypothetical protein complement(1921989..1922486) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112494 YP_002997684.1 CDS pgi NC_012891.1 1922748 1924097 R functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis; catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate; member of PGI family; glucose-6-phosphate isomerase complement(1922748..1924097) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112495 YP_002997685.1 CDS SDEG_1989 NC_012891.1 1924337 1924948 R similar to hypothetical protein; hypothetical protein [Streptococcus dysgalactiae subsp. equisimilis]; hypothetical protein complement(1924337..1924948) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111285 YP_002997686.1 CDS SDEG_1990 NC_012891.1 1925033 1925653 R similar to hypothetical protein [Streptococcus dysgalactiae subsp. equisimilis]; hypothetical protein complement(1925033..1925653) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112496 YP_002997687.1 CDS spegg4 NC_012891.1 1925738 1926442 R similar to exotoxin G variant 4 [Streptococcus dysgalactiae subsp. equisimilis]; exotoxin G variant 4 complement(1925738..1926442) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112497 YP_002997688.1 CDS SDEG_1992 NC_012891.1 1926861 1927301 D similar to hypothetical protein [Streptococcus dysgalactiae subsp. equisimilis]; hypothetical protein 1926861..1927301 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110495 YP_002997689.1 CDS SDEG_1993 NC_012891.1 1927307 1928086 D similar to peptidoglycan endo-beta-N-acetylglucosaminidase [Streptococcus pyogenes MGAS10394]; peptidoglycan endo-beta-N-acetylglucosaminidase 1927307..1928086 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112498 YP_002997690.1 CDS SDEG_1994 NC_012891.1 1928188 1928715 R similar to tRNA-specific adenosine deaminase [Streptococcus pyogenes MGAS10394]; tRNA-specific adenosine deaminase complement(1928188..1928715) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112499 YP_002997691.1 CDS SDEG_1995 NC_012891.1 1928715 1929494 R similar to metal-dependent hydrolase [Streptococcus pyogenes MGAS10394]; metal-dependent hydrolase complement(1928715..1929494) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112500 YP_002997692.1 CDS bioY NC_012891.1 1929634 1930173 R similar to BioY protein [Streptococcus pyogenes MGAS10750]; biotin transporter complement(1929634..1930173) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112501 YP_002997693.1 CDS SDEG_1997 NC_012891.1 1930177 1930488 R similar to zinc finger protein [Streptococcus pyogenes MGAS6180]; hypothetical protein complement(1930177..1930488) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112376 YP_002997694.1 CDS tgt NC_012891.1 1930693 1931835 R Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr); queuine tRNA-ribosyltransferase complement(1930693..1931835) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112502 YP_002997695.1 CDS SDEG_1999 NC_012891.1 1932055 1932921 D similar to integral membrane protein [Streptococcus pyogenes MGAS6180]; integral membrane protein 1932055..1932921 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110516 YP_002997696.1 CDS perR NC_012891.1 1933042 1933509 R similar to ferric uptake regulation protein [Streptococcus pyogenes MGAS5005]; ferric uptake regulation protein complement(1933042..1933509) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112503 YP_002997697.1 CDS SDEG_2001 NC_012891.1 1933576 1934016 R similar to CoA binding protein [Streptococcus pyogenes MGAS10270]; CoA binding protein complement(1933576..1934016) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111282 YP_002997698.1 CDS SDEG_2002 NC_012891.1 1934223 1936865 R has 3'-5' exonuclease, 5'-3' exonuclease and 5'-3'polymerase activities, primarily functions to fill gaps during DNA replication and repair; DNA polymerase I complement(1934223..1936865) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112504 YP_002997699.1 CDS opuABC NC_012891.1 1937013 1938740 R similar to glycine betaine-binding protein / glycine betaine transport system permease protein [Streptococcus pyogenes MGAS10750]; glycine betaine-binding protein/glycinebetaine transport system permease complement(1937013..1938740) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112505 YP_002997700.1 CDS opuAA NC_012891.1 1938758 1939954 R similar to glycine betaine transport ATP-binding protein [Streptococcus pyogenes str. Manfredo]; glycine betaine transport ATP-binding protein complement(1938758..1939954) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111744 YP_002997701.1 CDS SDEG_2005 NC_012891.1 1940386 1941330 R similar to diacylglycerol kinase catalytic subunit [Enterococcus faecalis; transcriptional regulator complement(1940386..1941330) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111743 YP_002997702.1 CDS SDEG_2006 NC_012891.1 1941510 1942601 R similar to metal-dependent hydrolase [Streptococcus pyogenes MGAS10394]; L-ascorbate 6-phosphate lactonase complement(1941510..1942601) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112506 YP_002997703.1 CDS SDEG_2007 NC_012891.1 1942898 1944544 R similar to transcription antiterminator BglG family [Streptococcus pyogenes MGAS10394]; BglG family transcription antiterminator complement(1942898..1944544) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112507 YP_002997704.1 CDS araD NC_012891.1 1944827 1945543 R catalyzes the formation of D-xylulose 5-phosphate from L-ribulose 5-phosphate in the L-arabinose and L-ascorbate degradation pathways; L-ribulose-5-phosphate 4-epimerase complement(1944827..1945543) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112508 YP_002997705.1 CDS SDEG_2009 NC_012891.1 1945545 1946408 R L-xylulose 5-phosphate 3-epimerase activity not yet demonstrated; may be involved in the utilization of 2,3-diketo-L-gulonate; L-xylulose 5-phosphate 3-epimerase complement(1945545..1946408) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112330 YP_002997706.1 CDS ulaD NC_012891.1 1946412 1947074 R catalyzes the formation of L-xylulose-5-phosphate from 3-keto-L-gulonate-6-phosphate in anaerobic L-ascorbate utilization; 3-keto-L-gulonate-6-phosphate decarboxylase complement(1946412..1947074) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112509 YP_002997707.1 CDS SDEG_2011 NC_012891.1 1947183 1947674 R similar to PTS system 3-keto-L-gulonate specific IIA component [Streptococcus pyogenes MGAS10750]; PTS system 3-keto-L-gulonate specific transporter subunit IIA complement(1947183..1947674) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111941 YP_002997708.1 CDS SDEG_2012 NC_012891.1 1947795 1948073 R similar to PTS system 3-keto-L-gulonate specific IIB component [Streptococcus pyogenes MGAS10394]; PTS system 3-keto-L-gulonate specific transporter subunit IIB complement(1947795..1948073) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112510 YP_002997709.1 CDS ulaA NC_012891.1 1948144 1949577 R membrane component; functions with enzymes IIB (sgaB; ulaB) and IIA (sgaA; ulaC) enzyme I and HPr for anaerobic utilization and uptake of L-ascorbate; sgaTBA are regulated by yifQ as well as Crp and Fnr; PTS system ascorbate-specific transporter subunit IIC complement(1948144..1949577) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112511 YP_002997710.1 CDS leuS NC_012891.1 1949882 1952383 R leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase; leucyl-tRNA synthetase complement(1949882..1952383) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111940 YP_002997711.1 CDS SDEG_2016 NC_012891.1 1953272 1953436 R similar to hypothetical protein MGAS2096 Spy1064 [Streptococcus pyogenes MGAS2096]; hypothetical protein complement(1953272..1953436) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112512 YP_002997712.1 CDS SDEG_2017 NC_012891.1 1953454 1953957 D similar to transposase [Streptococcus pyogenes MGAS10750]; transposase 1953454..1953957 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112513 YP_002997713.1 CDS SDEG_2018 NC_012891.1 1953965 1954411 D similar to transposase [Streptococcus pyogenes MGAS10394]; transposase 1953965..1954411 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112514 YP_002997714.1 CDS SDEG_2019 NC_012891.1 1954464 1954754 D similar to ISSag4 transposase orfA [Streptococcus agalactiae A909]; ISSag4, transposase orfA 1954464..1954754 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112515 YP_002997715.1 CDS SDEG_2020 NC_012891.1 1954790 1955230 D similar to ISSdy1 transposase OrfB [Streptococcus agalactiae 2603V/R]; ISSdy1, transposase OrfB 1954790..1955230 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112516 YP_002997716.1 CDS SDEG_2021 NC_012891.1 1955157 1955501 D similar to ISSdy1 transposase OrfB [Streptococcus agalactiae 2603V/R]; ISSdy1, transposase OrfB 1955157..1955501 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112517 YP_002997717.1 CDS SDEG_2022 NC_012891.1 1955580 1955897 R no hit; hypothetical protein complement(1955580..1955897) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112518 YP_002997718.1 CDS SDEG_2023 NC_012891.1 1956440 1958074 R similar to ABC transporter ATP-binding /membrane spanning permease - possible multidrug resistance [Carnobacterium sp. AT7]; ABC transporter ATP-binding protein/permease complement(1956440..1958074) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112519 YP_002997719.1 CDS SDEG_2024 NC_012891.1 1958059 1959042 R no hit; hypothetical protein complement(1958059..1959042) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112520 YP_002997720.1 CDS SDEG_2025 NC_012891.1 1959917 1960780 R similar to transposase [Streptococcus pyogenes MGAS2096]; transposase complement(1959917..1960780) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112521 YP_002997721.1 CDS SDEG_2026 NC_012891.1 1961358 1961735 R similar to hypothetical protein M28 Spy0140 [Streptococcus pyogenes MGAS6180]; hypothetical protein complement(1961358..1961735) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112522 YP_002997722.1 CDS slo NC_012891.1 1961986 1963710 R similar to streptolysin O precursor (Thiol-activated cytolysin); streptolysin O complement(1961986..1963710) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112523 YP_002997723.1 CDS ifs NC_012891.1 1963725 1964210 R similar to streptococcal NAD glycohydrolase inhibitor [Streptococcus pyogenes MGAS10270]; streptococcal NAD glycohydrolase inhibitor complement(1963725..1964210) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110489 YP_002997724.1 CDS nga NC_012891.1 1964215 1965567 R similar to NADase [Streptococcus dysgalactiae subsp. equisimilis]; NADase complement(1964215..1965567) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112048 YP_002997725.1 CDS nusG NC_012891.1 1965924 1966478 R Modulates Rho-dependent transcription termination; transcription antitermination protein NusG complement(1965924..1966478) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111710 YP_002997726.1 CDS secE NC_012891.1 1966681 1966857 R forms a complex with SecY and SecG; SecYEG forms a protein-conducting channel to which secA binds and translocates targeted polypeptides across the cytoplasmic membrane, a process driven by ATP and a proton-motive force; preprotein translocase subunit SecE complement(1966681..1966857) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111727 YP_002997727.1 CDS rpmG NC_012891.1 1966870 1967022 R in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group have the CXXC motif; 50S ribosomal protein L33 complement(1966870..1967022) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110478 YP_002997728.1 CDS pbp2 NC_012891.1 1967071 1969419 R similar to penicillin-binding protein 2a [Streptococcus pyogenes SSI-1]; penicillin-binding protein 2a complement(1967071..1969419) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111084 YP_002997729.1 CDS SDEG_2034 NC_012891.1 1969458 1969838 R similar to translation initiation inhibitor [Streptococcus equi subsp. zooepidemicus MGCS10565]; translation initiation inhibitor complement(1969458..1969838) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111755 YP_002997730.1 CDS SDEG_2035 NC_012891.1 1970183 1970374 D similar to hypothetical cytosolic protein [Streptococcus pyogenes MGAS10750]; hypothetical protein 1970183..1970374 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112524 YP_002997731.1 CDS SDEG_2036 NC_012891.1 1970244 1971269 D similar to ribosomal large subunit pseudouridine synthase D [Streptococcus pyogenes MGAS6180]; ribosomal large subunit pseudouridine synthase D 1970244..1971269 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112525 YP_002997732.1 CDS SDEG_2037 NC_012891.1 1971371 1973008 R similar to hypothetical protein M5005 Spy 1757 [Streptococcus pyogenes MGAS5005]; hypothetical protein complement(1971371..1973008) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112526 YP_002997733.1 CDS SDEG_2038 NC_012891.1 1973289 1974785 D similar to dipeptidase [Streptococcus pyogenes MGAS10270]; dipeptidase 1973289..1974785 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112527 YP_002997734.1 CDS SDEG_2039 NC_012891.1 1975118 1975585 D similar to MutT/Nudix family protein [Streptococcus equi subsp. zooepidemicus MGCS10565]; MutT/Nudix family protein 1975118..1975585 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112528 YP_002997735.1 CDS groEL NC_012891.1 1975802 1977427 R 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth; chaperonin GroEL complement(1975802..1977427) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112529 YP_002997736.1 CDS groES NC_012891.1 1977463 1977753 R 10 kDa chaperonin; Cpn10; GroES; forms homoheptameric ring; binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it; folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES; release of the folded substrate is dependent on ATP binding and hydrolysis in the trans ring; co-chaperonin GroES complement(1977463..1977753) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112019 YP_002997737.1 CDS clpC NC_012891.1 1977931 1980375 R similar to negative regulator of genetic competence clpC/mecB [Streptococcus pyogenes MGAS10270]; negative regulator of genetic competence clpC/mecB complement(1977931..1980375) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112020 YP_002997738.1 CDS ctsR NC_012891.1 1980375 1980836 R similar to transcriptional regulator ctsR [Streptococcus pyogenes MGAS2096]; transcriptional regulator ctsR complement(1980375..1980836) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111621 YP_002997739.1 CDS csp NC_012891.1 1981032 1981241 R similar to cold shock protein [Streptococcus pyogenes MGAS5005]; cold shock protein complement(1981032..1981241) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111653 YP_002997740.1 CDS paaB NC_012891.1 1981399 1981887 R similar to transposase [Streptococcus criceti]; transposase complement(1981399..1981887) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111651 YP_002997741.1 CDS SDEG_2046 NC_012891.1 1981842 1982261 R similar to transposase [Streptococcus pyogenes MGAS2096]; transposase complement(1981842..1982261) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111748 YP_002997742.1 CDS SDEG_2047 NC_012891.1 1982761 1983309 D similar to amidohydrolase 2 [Sphingomonas wittichii RW1]; amidohydrolase 2 1982761..1983309 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112530 YP_002997743.1 CDS SDEG_2048 NC_012891.1 1983340 1983588 D similar to amidohydrolase 2 [Sphingomonas wittichii RW1]; amidohydrolase 2 1983340..1983588 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112531 YP_002997744.1 CDS tra NC_012891.1 1983909 1984271 R similar to IS1562 transposase [Streptococcus pyogenes MGAS8232]; IS1562 transposase complement(1983909..1984271) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112532 YP_002997745.1 CDS SDEG_2050 NC_012891.1 1984383 1984727 R similar to transposase [Streptococcus pyogenes MGAS10394]; transposase complement(1984383..1984727) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111923 YP_002997746.1 CDS SDEG_2051 NC_012891.1 1984944 1985033 R similar to transposase [Streptococcus pyogenes MGAS10750]; transposase complement(1984944..1985033) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112533 YP_002997747.1 CDS ahpC NC_012891.1 1985728 1986288 D similar to alkyl hydroperoxidase [Streptococcus pyogenes M1 GAS]; alkyl hydroperoxidase 1985728..1986288 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112535 YP_002997748.1 CDS ahpF NC_012891.1 1986309 1987841 D similar to NADH dehydrogenase [Streptococcus pyogenes str. Manfredo]; NADH dehydrogenase 1986309..1987841 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112317 YP_002997749.1 CDS hutI NC_012891.1 1987899 1989185 R catalyzing the hydrolysis of 4-imidazolone-5-propionate to N-formimidoyl-L-glutamate, the third step in the histidine degradation pathway; imidazolonepropionase complement(1987899..1989185) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112318 YP_002997750.1 CDS hutU NC_012891.1 1989541 1991571 D catalyzes the formation of 4-imidazolone-5-propanoate from urocanate during histidine metabolism; urocanate hydratase 1989541..1991571 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112043 YP_002997751.1 CDS SDEG_2057 NC_012891.1 1991660 1992559 D similar to glutamate formiminotransferase [Streptococcus pyogenes MGAS10394]; glutamate formiminotransferase 1991660..1992559 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112044 YP_002997752.1 CDS SDEG_2058 NC_012891.1 1992570 1993196 D similar to formiminotetrahydrofolate cyclodeaminase [Streptococcus pyogenes MGAS2096]; formiminotetrahydrofolate cyclodeaminase 1992570..1993196 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112536 YP_002997753.1 CDS fhs2 NC_012891.1 1993214 1994887 D catalyzes the formation of 10-formyltetrahydrofolate from formate and tetrahydrofolate; formate--tetrahydrofolate ligase 1993214..1994887 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112537 YP_002997754.1 CDS SDEG_2060 NC_012891.1 1994909 1995505 D similar to hypothetical protein spyM18 2145 [Streptococcus pyogenes MGAS8232]; hypothetical protein 1994909..1995505 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111891 YP_002997755.1 CDS SDEG_2061 NC_012891.1 1995734 1997077 D similar to aminoacid permease [Streptococcus pyogenes MGAS10394]; amino acid permease 1995734..1997077 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112538 YP_002997756.1 CDS hutH NC_012891.1 1997089 1998630 D catalyzes the degradation of histidine to urocanate and ammmonia; histidine ammonia-lyase 1997089..1998630 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112539 YP_002997757.1 CDS hutG NC_012891.1 1998807 1999802 D catalyzes the formation of glutamate and formamide from N-formimidoyl-L-glutamate; formimidoylglutamase 1998807..1999802 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112042 YP_002997758.1 CDS SDEG_2064 NC_012891.1 1999833 2002907 R similar to transcriptional regulator LuxR family [Streptococcus pyogenesMGAS10750]; LuxR family transcriptional regulator complement(1999833..2002907) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112041 YP_002997759.1 CDS rpsB NC_012891.1 2003166 2003933 D one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit; 30S ribosomal protein S2 2003166..2003933 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112540 YP_002997760.1 CDS tsf NC_012891.1 2004067 2005107 D EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu; elongation factor Ts 2004067..2005107 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111094 YP_002997761.1 CDS pepO NC_012891.1 2005274 2007169 R similar to oligoendopeptidase O [Streptococcus pyogenes MGAS2096]; oligoendopeptidase O complement(2005274..2007169) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111935 YP_002997762.1 CDS dexS NC_012891.1 2007377 2009005 R similar to trehalose-6-phosphate hydrolase [Streptococcus pyogenes MGAS2096]; trehalose-6-phosphate hydrolase complement(2007377..2009005) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111278 YP_002997763.1 CDS SDEG_2069 NC_012891.1 2009072 2011096 R similar to PTS system trehalose-specific IIBC component / PTS system trehalose-specific IIA component [Streptococcus pyogenes MGAS2096]; PTS system trehalose-specific transporter subunit IIABC complement(2009072..2011096) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111670 YP_002997764.1 CDS SDEG_2070 NC_012891.1 2011307 2012020 D similar to trehalose operon transcriptional repressor [Streptococcus pyogenes MGAS10394]; trehalose operon transcriptional repressor 2011307..2012020 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110772 YP_002997765.1 CDS SDEG_2071 NC_012891.1 2012299 2012538 R similar to hypothetical protein spyM18 2160 [Streptococcus pyogenes MGAS8232]; hypothetical protein complement(2012299..2012538) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110773 YP_002997766.1 CDS yaaA NC_012891.1 2013719 2014450 D similar to hypothetical cytosolic protein [Streptococcus pyogenes MGAS10750]; hypothetical protein 2013719..2014450 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110775 YP_002997767.1 CDS nrdG NC_012891.1 2014624 2015238 R similar to anaerobic ribonucleoside-triphosphate reductase activating protein [Streptococcus pyogenes MGAS10394]; anaerobic ribonucleoside-triphosphate reductase activating protein complement(2014624..2015238) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111956 YP_002997768.1 CDS SDEG_2075 NC_012891.1 2015242 2015745 R similar to acetyltransferase [Streptococcus pyogenes MGAS10750]; acetyltransferase complement(2015242..2015745) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111720 YP_002997769.1 CDS SDEG_2076 NC_012891.1 2015754 2016689 R similar to Mvi [Streptococcus pyogenes MGAS10394]; virulence factor complement(2015754..2016689) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110776 YP_002997770.1 CDS SDEG_2077 NC_012891.1 2016718 2016864 R similar to hypothetical protein STRINF 00502 [Streptococcus infantarius subsp. infantarius ATCC BAA-102]; hypothetical protein complement(2016718..2016864) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110777 YP_002997771.1 CDS nrdD NC_012891.1 2017050 2019248 R Catalyzes the reduction of nucleoside 5'-triphosphates to 2'-deoxynucleoside 5'-triphosphates; anaerobic ribonucleoside triphosphate reductase complement(2017050..2019248) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110778 YP_002997772.1 CDS SDEG_2079 NC_012891.1 2019345 2020907 R similar to hypothetical membrane spanning protein [Streptococcus pyogenes MGAS2096]; hypothetical protein complement(2019345..2020907) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111715 YP_002997773.1 CDS SDEG_2080 NC_012891.1 2021243 2021548 R similar to hypothetical cytosolic protein [Streptococcus pyogenes MGAS10750]; hypothetical protein complement(2021243..2021548) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110779 YP_002997774.1 CDS SDEG_2081 NC_012891.1 2021559 2021978 R similar to Holliday junction resolvase-like protein [Streptococcus pyogenes MGAS8232]; Holliday junction resolvase-like protein complement(2021559..2021978) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110780 YP_002997775.1 CDS SDEG_2082 NC_012891.1 2021975 2022244 R similar to hypothetical protein M6 Spy1796 [Streptococcus pyogenes MGAS10394]; hypothetical protein complement(2021975..2022244) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110781 YP_002997776.1 CDS spxA NC_012891.1 2022356 2022754 R the anti-alpha factor Spx interacts with RNA polymerase alpha subunit C-terminal domain in a region that interacts with the sigma 70 subunit and may interfere with activation of promoters; in Bacillus subtilis this protein is a substrate for ClpXP protease; blocks transcription of the competence regulatory gene encoded by the srf operon; regulates a number of genes involved in thiol homeostasis including trxA and trxB; monomeric member of ArsC family of proteins; does not bind DNA; contains a disulfide bond between C10 and C13 which may sense disulfide stress; transcriptional regulator Spx complement(2022356..2022754) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110782 YP_002997777.1 CDS recA NC_012891.1 2023048 2024184 R catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs; recombinase A complement(2023048..2024184) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110502 YP_002997778.1 CDS cinA NC_012891.1 2024289 2025560 R similar to colligrin [Streptococcus pyogenes MGAS10270]; competence damage-inducible protein A complement(2024289..2025560) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111031 YP_002997779.1 CDS SDEG_2086 NC_012891.1 2025684 2026040 R similar to glyoxalase family protein superfamily [Streptococcus gordonii str. Challis substr. CH1]; glyoxalase complement(2025684..2026040) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111614 YP_002997780.1 CDS tag NC_012891.1 2026040 2026612 R similar to DNA-3-methyladenine glycosylase I [Streptococcus pyogenes str. Manfredo]; DNA-3-methyladenine glycosylase I complement(2026040..2026612) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110783 YP_002997781.1 CDS ruvA NC_012891.1 2026622 2027215 R plays an essential role in ATP-dependent branch migration of the Holliday junction; Holliday junction DNA helicase RuvA complement(2026622..2027215) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110512 YP_002997782.1 CDS lmrP NC_012891.1 2027217 2028437 R similar to transporter protein [Streptococcus pyogenes str. Manfredo]; transporter protein complement(2027217..2028437) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110451 YP_002997783.1 CDS mutL NC_012891.1 2028448 2030430 R This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. Promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex; DNA mismatch repair protein complement(2028448..2030430) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110905 YP_002997784.1 CDS mutS NC_012891.1 2030558 2033113 R This protein performs the mismatch recognition step during the DNA repair process; DNA mismatch repair protein MutS complement(2030558..2033113) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111693 YP_002997785.1 CDS SDEG_2092 NC_012891.1 2033100 2033453 R similar to hypothetical protein Sez 1884 [Streptococcus equi subsp. zooepidemicus MGCS10565]; hypothetical protein complement(2033100..2033453) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111695 YP_002997786.1 CDS argR2 NC_012891.1 2033450 2033887 R similar to arginine repressor [Streptococcus pyogenes MGAS5005]; arginine repressor complement(2033450..2033887) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110784 YP_002997787.1 CDS argS NC_012891.1 2034176 2035867 D catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase; arginyl-tRNA synthetase 2034176..2035867 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112336 YP_002997788.1 CDS msrA NC_012891.1 2035937 2037334 R similar to ABC transporter ATP-binding protein [Streptococcus equi subsp. zooepidemicus MGCS10565]; ABC transporter ATP-binding protein complement(2035937..2037334) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112337 YP_002997789.1 CDS SDEG_2096 NC_012891.1 2037512 2038426 R similar to transporter [Streptococcus equi subsp. zooepidemicus MGCS10565]; transporter complement(2037512..2038426) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110945 YP_002997790.1 CDS SDEG_2097 NC_012891.1 2038456 2039355 R similar to hypothetical membrane spanning protein [Streptococcus pyogenes MGAS10394]; hypothetical protein complement(2038456..2039355) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110785 YP_002997791.1 CDS SDEG_2098 NC_012891.1 2039376 2040317 R similar to hypothetical membrane spanning protein [Streptococcus pyogenes MGAS5005]; hypothetical protein complement(2039376..2040317) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110786 YP_002997792.1 CDS aspS NC_012891.1 2040310 2042058 R catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes; aspartyl-tRNA synthetase complement(2040310..2042058) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110787 YP_002997793.1 CDS hisS NC_012891.1 2042396 2043676 R catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG; histidyl-tRNA synthetase complement(2042396..2043676) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112353 YP_002997794.1 CDS rpmF NC_012891.1 2044066 2044248 D some L32 proteins have zinc finger motifs consisting of CXXC while others do not; 50S ribosomal protein L32 2044066..2044248 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112032 YP_002997795.1 CDS rpmG NC_012891.1 2044264 2044413 D in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif; 50S ribosomal protein L33 2044264..2044413 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111083 YP_002997796.1 CDS cadD NC_012891.1 2044705 2045319 D similar to cadmium resistance protein [Streptococcus pyogenes MGAS5005]; cadmium resistance protein 2044705..2045319 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111085 YP_002997797.1 CDS cadC NC_012891.1 2045301 2045669 D similar to cadmium efflux system accessory protein [Streptococcus pyogenes MGAS5005]; cadmium efflux system accessory protein 2045301..2045669 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111600 YP_002997798.1 CDS SDEG_2105 NC_012891.1 2045692 2046636 D similar to hypothetical protein MGAS10270 Spy1911 [Streptococcus pyogenes MGAS10270]; hypothetical protein 2045692..2046636 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111599 YP_002997799.1 CDS SDEG_2106 NC_012891.1 2046702 2047454 D similar to FtsK/SpoIIIE family [Streptococcus pyogenes MGAS10750]; FtsK/SpoIIIE family 2046702..2047454 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110788 YP_002997800.1 CDS SDEG_2107 NC_012891.1 2047451 2048053 D similar to hypothetical protein SPy 2166 [Streptococcus pyogenes M1 GAS]; hypothetical protein 2047451..2048053 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110789 YP_002997801.1 CDS SDEG_2108 NC_012891.1 2048531 2048815 R similar to transcriptional regulator [Streptococcus pyogenes MGAS2096]; transcriptional regulator complement(2048531..2048815) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110790 YP_002997802.1 CDS SDEG_2109 NC_012891.1 2049023 2049181 R similar to hypothetical protein M6 Spy1842 [Streptococcus pyogenes MGAS10394]; hypothetical protein complement(2049023..2049181) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110791 YP_002997803.1 CDS SDEG_2110 NC_012891.1 2049266 2050108 D similar to integral membrane protein [Streptococcus pyogenes MGAS6180]; integral membrane protein 2049266..2050108 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110792 YP_002997804.1 CDS SDEG_2111 NC_012891.1 2050155 2050796 R similar to NUDIX hydrolase [Streptococcus pyogenes str. Manfredo]; NUDIX hydrolase complement(2050155..2050796) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110793 YP_002997805.1 CDS SDEG_2112 NC_012891.1 2051000 2051326 D similar to hypothetical protein SpyM3 1828 [Streptococcus pyogenes MGAS315]; hypothetical protein 2051000..2051326 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110794 YP_002997806.1 CDS SDEG_2113 NC_012891.1 2051313 2051900 D similar to hypothetical membrane associated protein [Streptococcus pyogenes MGAS9429]; hypothetical protein 2051313..2051900 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110795 YP_002997807.1 CDS SDEG_2114 NC_012891.1 2051897 2052970 D similar to hypothetical membrane associated protein [Streptococcus pyogenes MGAS2096]; hypothetical protein 2051897..2052970 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110796 YP_002997808.1 CDS SDEG_2115 NC_012891.1 2053095 2055389 R similar to phage protein [Streptococcus pyogenes MGAS6180]; phage protein complement(2053095..2055389) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110797 YP_002997809.1 CDS SDEG_2116 NC_012891.1 2055503 2056036 D similar to transcriptional regulator (TetR/AcrR family) [Streptococcus pyogenes MGAS315]; TetR family transcriptional regulator 2055503..2056036 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110798 YP_002997810.1 CDS SDEG_2117 NC_012891.1 2056033 2057442 R similar to transposase [Streptococcus pyogenes MGAS10394]; transposase complement(2056033..2057442) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110799 YP_002997811.1 CDS SDEG_2118 NC_012891.1 2057426 2057533 R similar to transposase [Streptococcus pyogenes MGAS10750]; transposase complement(2057426..2057533) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110800 YP_002997812.1 CDS SDEG_2119 NC_012891.1 2057961 2058245 R similar to RelE-domain protein [Streptococcus pyogenes MGAS6180]; RelE-domain-containing protein complement(2057961..2058245) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110801 YP_002997813.1 CDS SDEG_2120 NC_012891.1 2058220 2058492 R similar to RelB protein [Streptococcus pyogenes MGAS10270]; RelB protein complement(2058220..2058492) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110802 YP_002997814.1 CDS SDEG_2121 NC_012891.1 2058584 2058970 R similar to phage encoded transcriptional regulator ArpU family [Streptococcus pyogenes MGAS10394]; ArpU family phage encoded transcriptional regulator complement(2058584..2058970) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110803 YP_002997815.1 CDS SDEG_2122 NC_012891.1 2058945 2059307 R similar to phage protein [Streptococcus pyogenes MGAS6180]; phage protein complement(2058945..2059307) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110804 YP_002997816.1 CDS SDEG_2123 NC_012891.1 2059578 2059799 R similar to phage protein [Streptococcus pyogenes MGAS6180]; phage protein complement(2059578..2059799) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110805 YP_002997817.1 CDS SDEG_2124 NC_012891.1 2059799 2060053 R similar to phage protein [Streptococcus pyogenes MGAS6180]; phage protein complement(2059799..2060053) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110806 YP_002997818.1 CDS SDEG_2125 NC_012891.1 2060037 2060375 R similar to phage protein [Streptococcus pyogenes MGAS6180]; phage protein complement(2060037..2060375) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110807 YP_002997819.1 CDS SDEG_2126 NC_012891.1 2060458 2060706 R similar to phage protein [Streptococcus pyogenes MGAS6180]; phage protein complement(2060458..2060706) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110808 YP_002997820.1 CDS SDEG_2127 NC_012891.1 2060716 2061501 R similar to phage protein [Streptococcus pyogenes MGAS6180]; phage protein complement(2060716..2061501) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110809 YP_002997821.1 CDS SDEG_2128 NC_012891.1 2061590 2061739 R similar to phage protein [Streptococcus pyogenes MGAS6180]; phage protein complement(2061590..2061739) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110810 YP_002997822.1 CDS SDEG_2129 NC_012891.1 2061753 2061998 R similar to phage protein [Streptococcus pyogenes MGAS6180]; phage protein complement(2061753..2061998) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110811 YP_002997823.1 CDS SDEG_2130 NC_012891.1 2061973 2062320 R similar to phage protein [Streptococcus pyogenes MGAS6180]; phage protein complement(2061973..2062320) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110812 YP_002997824.1 CDS SDEG_2131 NC_012891.1 2062322 2062495 R similar to phage protein [Streptococcus phage 10270.4]; phage protein complement(2062322..2062495) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110813 YP_002997825.1 CDS SDEG_2132 NC_012891.1 2062501 2062674 R similar to phage protein [Streptococcus pyogenes MGAS6180]; phage protein complement(2062501..2062674) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110814 YP_002997826.1 CDS SDEG_2133 NC_012891.1 2062961 2064574 R similar to bacteriophage resistance protein [Streptococcus pyogenes MGAS10270]; bacteriophage resistance protein complement(2062961..2064574) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110815 YP_002997827.1 CDS SDEG_2134 NC_012891.1 2064564 2065085 R similar to phage protein [Streptococcus pyogenes MGAS10270]; phage protein complement(2064564..2065085) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110816 YP_002997828.1 CDS SDEG_2135 NC_012891.1 2065095 2065463 R similar to phage protein [Streptococcus pyogenes MGAS10270]; phage protein complement(2065095..2065463) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110817 YP_002997829.1 CDS SDEG_2136 NC_012891.1 2065687 2066019 R similar to phageprotein [Streptococcus pyogenes MGAS6180]; phage protein complement(2065687..2066019) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110818 YP_002997830.1 CDS SDEG_2137 NC_012891.1 2066243 2066491 R similar to prophage antirepressor [Streptococcus pyogenes MGAS10270]; prophage antirepressor complement(2066243..2066491) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110819 YP_002997831.1 CDS SDEG_2138 NC_012891.1 2066548 2067111 R similar to phage antirepressor protein [Streptococcus pyogenes MGAS10270]; phage antirepressor protein complement(2066548..2067111) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110820 YP_002997832.1 CDS SDEG_2139 NC_012891.1 2067127 2067315 R similar to phage protein [Streptococcus pyogenes MGAS10270]; phage protein complement(2067127..2067315) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110821 YP_002997833.1 CDS SDEG_2140 NC_012891.1 2067484 2067927 D similar to phage transcriptional regulator Cro/CI family [Streptococcus phage 10270.5]; phage transcriptional regulator, Cro/CI family 2067484..2067927 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110822 YP_002997834.1 CDS SDEG_2141 NC_012891.1 2068238 2068762 D no hit; hypothetical protein 2068238..2068762 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110823 YP_002997835.1 CDS SDEG_2142 NC_012891.1 2069006 2070169 D similar to DNA integration/recombination /inversion protein [Streptococcus phage 10270.5]; DNA integration/recombination/inversion protein 2069006..2070169 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110824 YP_002997836.1 CDS rpsD NC_012891.1 2070326 2070937 R primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination; 30S ribosomal protein S4 complement(2070326..2070937) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110825 YP_002997837.1 CDS SDEG_2144 NC_012891.1 2071746 2072018 R similar to hypothetical protein spyM18 2216 [Streptococcus pyogenes MGAS8232]; hypothetical protein complement(2071746..2072018) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111095 YP_002997838.1 CDS holB NC_012891.1 2072034 2073410 R unwinds double stranded DNA; replicative DNA helicase complement(2072034..2073410) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110826 YP_002997839.1 CDS rplI NC_012891.1 2073431 2073883 R in Escherichia coli this protein is wrapped around the base of the L1 stalk; 50S ribosomal protein L9 complement(2073431..2073883) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112035 YP_002997840.1 CDS SDEG_2147 NC_012891.1 2073880 2075856 R similar to phosphoesterase DHH family protein [Streptococcus pyogenes MGAS2096]; phosphoesterase, DHH family protein complement(2073880..2075856) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111064 YP_002997841.1 CDS gidA NC_012891.1 2075947 2077845 R GidA; glucose-inhibited cell division protein A; involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U) of the wobble uridine base in some tRNAs; tRNA uridine 5-carboxymethylaminomethyl modification protein GidA complement(2075947..2077845) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110827 YP_002997842.1 CDS SDEG_2149 NC_012891.1 2077897 2078346 R similar to phosphohydrolase [Streptococcus pyogenes MGAS6180]; phosphohydrolase complement(2077897..2078346) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111992 YP_002997843.1 CDS SDEG_2150 NC_012891.1 2078560 2079168 R similar to hypothetical protein SAG2143 [Streptococcus agalactiae 2603V/R]; hypothetical protein complement(2078560..2079168) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110828 YP_002997844.1 CDS mnmA NC_012891.1 2079200 2080339 R catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs; tRNA-specific 2-thiouridylase MnmA complement(2079200..2080339) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110829 YP_002997845.1 CDS sdhB NC_012891.1 2080612 2081289 D similar to L-serinedehydratase beta subunit [Streptococcus pyogenes MGAS10750]; L-serine dehydratase subunit beta 2080612..2081289 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111928 YP_002997846.1 CDS sdhA NC_012891.1 2081301 2082173 D similar to L-serinedehydratase alpha subunit [Streptococcus pyogenes MGAS10270]; L-serine dehydratase subunit alpha 2081301..2082173 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110475 YP_002997847.1 CDS SDEG_2154 NC_012891.1 2082199 2082846 D similar to phosphoglycolate phosphatase [Streptococcus equi subsp. zooepidemicus MGCS10565]; phosphoglycolate phosphatase 2082199..2082846 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110474 YP_002997848.1 CDS SDEG_2155 NC_012891.1 2082909 2083523 R similar to transglycosylase SLT domain family protein [Streptococcus pyogenes MGAS10394]; transglycosylase complement(2082909..2083523) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110830 YP_002997849.1 CDS SDEG_2156 NC_012891.1 2083709 2084509 R similar to cobalt transport protein cbiQ [Streptococcus pyogenes MGAS10394]; cobalt transport protein cbiQ complement(2083709..2084509) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110831 YP_002997850.1 CDS cbiO NC_012891.1 2084502 2085344 R with CbiNQ forms the ABC transporter for cobalt import; Streptococcus has two adjacent copies of this gene; cobalt transporter ATP-binding subunit complement(2084502..2085344) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110832 YP_002997851.1 CDS cbiO NC_012891.1 2085320 2086159 R with CbiNQ forms the ABC transporter for cobalt import; Streptococcus has two adjacent copies of this gene; cobalt transporter ATP-binding subunit complement(2085320..2086159) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110833 YP_002997852.1 CDS pgsA NC_012891.1 2086162 2086704 R similar to CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase PgsA [Streptococcus equi subsp. zooepidemicus MGCS10565]; CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase complement(2086162..2086704) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110834 YP_002997853.1 CDS SDEG_2160 NC_012891.1 2086718 2087749 R similar to hypothetical membrane associated protein [Streptococcus pyogenes MGAS6180]; hypothetical protein complement(2086718..2087749) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111288 YP_002997854.1 CDS SDEG_2161 NC_012891.1 2087799 2089082 R similar to zinc protease [Streptococcus pyogenes MGAS10750]; zinc protease complement(2087799..2089082) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110835 YP_002997855.1 CDS SDEG_2162 NC_012891.1 2089084 2090328 R similar to zinc protease [Streptococcus pyogenes MGAS10394]; zinc protease complement(2089084..2090328) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110836 YP_002997856.1 CDS SDEG_2163 NC_012891.1 2090436 2091050 D similar to hypothetical cytosolic protein [Streptococcus pyogenes MGAS10750]; hypothetical protein 2090436..2091050 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110837 YP_002997857.1 CDS recF NC_012891.1 2091052 2092158 D Required for DNA replication; binds preferentially to single-stranded, linear DNA; recombination protein F 2091052..2092158 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110838 YP_002997858.1 CDS SDEG_2165 NC_012891.1 2092215 2093078 R similar to glucose uptake family protein [Streptococcus pyogenes MGAS9429]; glucose uptake family protein complement(2092215..2093078) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111033 YP_002997859.1 CDS guaB NC_012891.1 2093290 2094771 R catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate; inosine 5'-monophosphate dehydrogenase complement(2093290..2094771) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110839 YP_002997860.1 CDS trsA NC_012891.1 2094988 2096013 R catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; tryptophanyl-tRNA synthetase II complement(2094988..2096013) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112023 YP_002997861.1 CDS SDEG_2168 NC_012891.1 2096155 2096232 R similar to hypothetical protein M6 Spy1877 [Streptococcus pyogenes MGAS10394]; hypothetical protein complement(2096155..2096232) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111929 YP_002997862.1 CDS SDEG_2169 NC_012891.1 2096436 2097308 D similar to hypothetical protein SPy 2209 [Streptococcus pyogenes M1 GAS]; hypothetical protein 2096436..2097308 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110840 YP_002997863.1 CDS SDEG_2170 NC_012891.1 2097387 2099006 D similar to ABC transporter ATP-binding protein [Streptococcus pyogenes str. Manfredo]; ABC transporter ATP-binding protein 2097387..2099006 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110841 YP_002997864.1 CDS SDEG_2171 NC_012891.1 2099091 2101700 D similar to ABC transporter permease protein [Streptococcus pyogenes MGAS10270]; ABC transporter permease 2099091..2101700 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110842 YP_002997865.1 CDS SDEG_2174 NC_012891.1 2102464 2103309 D similar to insertion sequence IS1239 transposase [Streptococcus pyogenes str. Manfredo]; IS1239, transposase 2102464..2103309 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110845 YP_002997866.1 CDS SDEG_2176 NC_012891.1 2103552 2104031 R SPOUT methyltransferase family protein; crystal structure shows homodimer; in Escherichia coli this protein methylates pseudouridine at position 1915 of the 23S ribosomal RNA; rRNA large subunit methyltransferase complement(2103552..2104031) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110847 YP_002997867.1 CDS htrA NC_012891.1 2104243 2105466 D similar to endopeptidase DegP [Streptococcus pyogenes MGAS10750]; endopeptidase 2104243..2105466 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110848 YP_002997868.1 CDS parB NC_012891.1 2105525 2106331 D similar to chromosome partitioning protein [Streptococcus pyogenes MGAS6180]; chromosome partitioning protein 2105525..2106331 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112040 SDEG_0018 tRNA SDEG_0018 NC_012891.1 21154 21228 D tRNA-Ala 21154..21228 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110861 SDEG_0021 tRNA SDEG_0021 NC_012891.1 24516 24590 D tRNA-Val 24516..24590 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110864 SDEG_0022 tRNA SDEG_0022 NC_012891.1 24609 24681 D tRNA-Asp 24609..24681 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110865 SDEG_0023 tRNA SDEG_0023 NC_012891.1 24713 24785 D tRNA-Lys 24713..24785 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110866 SDEG_0024 tRNA SDEG_0024 NC_012891.1 24791 24872 D tRNA-Leu 24791..24872 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110867 SDEG_0025 tRNA SDEG_0025 NC_012891.1 24883 24955 D tRNA-Thr 24883..24955 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111759 SDEG_0026 tRNA SDEG_0026 NC_012891.1 24966 25037 D tRNA-Gly 24966..25037 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111760 SDEG_0027 tRNA SDEG_0027 NC_012891.1 25046 25130 D tRNA-Leu 25046..25130 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111761 SDEG_0028 tRNA SDEG_0028 NC_012891.1 25146 25219 D tRNA-Arg 25146..25219 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111762 SDEG_0029 tRNA SDEG_0029 NC_012891.1 25225 25300 D tRNA-Pro 25225..25300 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111763 SDEG_0030 tRNA SDEG_0030 NC_012891.1 25304 25379 D tRNA-Met 25304..25379 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111764 SDEG_0031 tRNA SDEG_0031 NC_012891.1 25399 25472 D tRNA-Met 25399..25472 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111765 SDEG_0032 tRNA SDEG_0032 NC_012891.1 25485 25574 D tRNA-Ser 25485..25574 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111766 SDEG_0033 tRNA SDEG_0033 NC_012891.1 25583 25658 D tRNA-Met 25583..25658 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111767 SDEG_0034 tRNA SDEG_0034 NC_012891.1 25674 25748 D tRNA-Phe 25674..25748 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111768 SDEG_0035 tRNA SDEG_0035 NC_012891.1 25757 25827 D tRNA-Gly 25757..25827 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111769 SDEG_0036 tRNA SDEG_0036 NC_012891.1 25853 25928 D tRNA-Ile 25853..25928 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111770 SDEG_0037 tRNA SDEG_0037 NC_012891.1 25934 26023 D tRNA-Ser 25934..26023 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111771 SDEG_0102 tRNA SDEG_0102 NC_012891.1 82558 82632 D tRNA-Ala 82558..82632 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111797 SDEG_0105 tRNA SDEG_0105 NC_012891.1 85921 85995 D tRNA-Val 85921..85995 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111800 SDEG_0106 tRNA SDEG_0106 NC_012891.1 86000 86072 D tRNA-Gly 86000..86072 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111801 SDEG_0107 tRNA SDEG_0107 NC_012891.1 86099 86174 D tRNA-Ile 86099..86174 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111802 SDEG_0108 tRNA SDEG_0108 NC_012891.1 86189 86262 D tRNA-Glu 86189..86262 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111803 SDEG_0109 tRNA SDEG_0109 NC_012891.1 86272 86361 D tRNA-Ser 86272..86361 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111804 SDEG_0110 tRNA SDEG_0110 NC_012891.1 86370 86445 D tRNA-Met 86370..86445 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111805 SDEG_0111 tRNA SDEG_0111 NC_012891.1 86461 86535 D tRNA-Phe 86461..86535 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111806 SDEG_0112 tRNA SDEG_0112 NC_012891.1 86554 86634 D tRNA-Tyr 86554..86634 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111807 SDEG_0113 tRNA SDEG_0113 NC_012891.1 86641 86711 D tRNA-Trp 86641..86711 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111808 SDEG_0114 tRNA SDEG_0114 NC_012891.1 86721 86795 D tRNA-His 86721..86795 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111809 SDEG_0115 tRNA SDEG_0115 NC_012891.1 86802 86875 D tRNA-Gln 86802..86875 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111810 SDEG_0116 tRNA SDEG_0116 NC_012891.1 86894 86977 D tRNA-Leu 86894..86977 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111811 SDEG_0213 tRNA SDEG_0213 NC_012891.1 187481 187555 R tRNA-Lys complement(187481..187555) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111481 SDEG_0313 tRNA SDEG_0313 NC_012891.1 284134 284208 D tRNA-Ala 284134..284208 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111404 SDEG_0316 tRNA SDEG_0316 NC_012891.1 287486 287559 D tRNA-Asn 287486..287559 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111407 SDEG_0317 tRNA SDEG_0317 NC_012891.1 287643 287716 D tRNA-Arg 287643..287716 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111408 SDEG_0335 tRNA SDEG_0335 NC_012891.1 306069 306154 D tRNA-Leu 306069..306154 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111416 SDEG_0362 tRNA SDEG_0362 NC_012891.1 338140 338214 D tRNA-Ala 338140..338214 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111430 SDEG_0365 tRNA SDEG_0365 NC_012891.1 341492 341565 D tRNA-Asn 341492..341565 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111433 SDEG_0366 tRNA SDEG_0366 NC_012891.1 341649 341722 D tRNA-Arg 341649..341722 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111434 SDEG_0697 tRNA SDEG_0697 NC_012891.1 666086 666157 D tRNA-Arg 666086..666157 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111072 SDEG_1164 tRNA SDEG_1164 NC_012891.1 1119752 1119823 R tRNA-Arg complement(1119752..1119823) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111516 SDEG_1167 tRNA SDEG_1167 NC_012891.1 1121255 1121329 R tRNA-Gln complement(1121255..1121329) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111093 SDEG_1168 tRNA SDEG_1168 NC_012891.1 1121378 1121458 R tRNA-Tyr complement(1121378..1121458) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111518 SDEG_1570 tRNA SDEG_1570 NC_012891.1 1523969 1524039 D tRNA-Thr 1523969..1524039 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111713 SDEG_1669 tRNA SDEG_1669 NC_012891.1 1606634 1606707 R tRNA-Glu complement(1606634..1606707) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112402 SDEG_1670 tRNA SDEG_1670 NC_012891.1 1606722 1606797 R tRNA-Ile complement(1606722..1606797) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112403 SDEG_1671 tRNA SDEG_1671 NC_012891.1 1606834 1606906 R tRNA-Thr complement(1606834..1606906) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112404 SDEG_1672 tRNA SDEG_1672 NC_012891.1 1606917 1606998 R tRNA-Leu complement(1606917..1606998) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112405 SDEG_1673 tRNA SDEG_1673 NC_012891.1 1607004 1607076 R tRNA-Lys complement(1607004..1607076) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112406 SDEG_1674 tRNA SDEG_1674 NC_012891.1 1607108 1607180 R tRNA-Asp complement(1607108..1607180) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112407 SDEG_1675 tRNA SDEG_1675 NC_012891.1 1607199 1607273 R tRNA-Val complement(1607199..1607273) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112408 SDEG_1678 tRNA SDEG_1678 NC_012891.1 1610561 1610635 R tRNA-Ala complement(1610561..1610635) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112411 SDEG_1794 tRNA SDEG_1794 NC_012891.1 1719676 1719762 R tRNA-Ser complement(1719676..1719762) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110630 SDEG_2052 tRNA SDEG_2052 NC_012891.1 1985257 1985327 R tRNA-Cys complement(1985257..1985327) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112534 SDEG_2172 tRNA SDEG_2172 NC_012891.1 2101920 2101995 R tRNA-Asn complement(2101920..2101995) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110843 SDEG_2173 tRNA SDEG_2173 NC_012891.1 2102027 2102101 R tRNA-Glu complement(2102027..2102101) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110844 SDEG_2175 tRNA SDEG_2175 NC_012891.1 2103391 2103464 D tRNA-Arg 2103391..2103464 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110846 SDEG_0017 rRNA SDEG_0017 NC_012891.1 19553 21103 D 16S ribosomal RNA 19553..21103 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110860 SDEG_0019 rRNA SDEG_0019 NC_012891.1 21535 24289 D 23S ribosomal RNA 21535..24289 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110862 SDEG_0020 rRNA SDEG_0020 NC_012891.1 24384 24500 D 5S ribosomal RNA 24384..24500 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8110863 SDEG_0101 rRNA SDEG_0101 NC_012891.1 80958 82507 D 16S ribosomal RNA 80958..82507 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111796 SDEG_0103 rRNA SDEG_0103 NC_012891.1 82939 85694 D 23S ribosomal RNA 82939..85694 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111798 SDEG_0104 rRNA SDEG_0104 NC_012891.1 85789 85905 D 5S ribosomal RNA 85789..85905 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111799 SDEG_0312 rRNA SDEG_0312 NC_012891.1 282530 284083 D 16S ribosomal RNA 282530..284083 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111403 SDEG_0314 rRNA SDEG_0314 NC_012891.1 284515 287269 D 23S ribosomal RNA 284515..287269 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111405 SDEG_0315 rRNA SDEG_0315 NC_012891.1 287364 287480 D 5S ribosomal RNA 287364..287480 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111406 SDEG_0361 rRNA SDEG_0361 NC_012891.1 336540 338089 D 16S ribosomal RNA 336540..338089 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111741 SDEG_0363 rRNA SDEG_0363 NC_012891.1 338521 341275 D 23S ribosomal RNA 338521..341275 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111431 SDEG_0364 rRNA SDEG_0364 NC_012891.1 341370 341486 D 5S ribosomal RNA 341370..341486 Streptococcus dysgalactiae subsp. equisimilis GGS_124 8111432 SDEG_1676 rRNA SDEG_1676 NC_012891.1 1607289 1607405 R 5S ribosomal RNA complement(1607289..1607405) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112409 SDEG_1677 rRNA SDEG_1677 NC_012891.1 1607500 1610254 R 23S ribosomal RNA complement(1607500..1610254) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112410 SDEG_1679 rRNA SDEG_1679 NC_012891.1 1610686 1612235 R 16S ribosomal RNA complement(1610686..1612235) Streptococcus dysgalactiae subsp. equisimilis GGS_124 8112412