-- dump date   	20140620_081841
-- class       	Genbank::misc_feature
-- table       	misc_feature_note
-- id	note
553482000001	chromosomal replication initiation protein; Reviewed; Region: dnaA; PRK00149
553482000002	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
553482000003	Walker A motif; other site
553482000004	ATP binding site [chemical binding]; other site
553482000005	Walker B motif; other site
553482000006	arginine finger; other site
553482000007	C-terminal domain of bacterial DnaA proteins. The DNA-binding C-terminal domain of DnaA contains a helix-turn-helix motif that specifically interacts with the DnaA box, a 9-mer motif that occurs repetitively in the replication origin oriC. Multiple...; Region: Bac_DnaA_C; cd06571
553482000008	DnaA box-binding interface [nucleotide binding]; other site
553482000009	HMMPfam hit to PF00308, Bacterial dnaA protein, score 6.5e-116
553482000010	PS00017 ATP/GTP-binding site motif A (P-loop).
553482000011	HMMPfam hit to PF08299, Bacterial dnaA protein helix-turn-helix, score 7.6e-36
553482000012	PS01008 DnaA protein signature.
553482000013	DNA polymerase III subunit beta; Validated; Region: PRK05643
553482000014	Beta clamp domain.  The beta subunit (processivity factor) of DNA polymerase III holoenzyme, refered to as the beta clamp, forms a ring shaped dimer that encircles dsDNA (sliding clamp) in bacteria.  The beta-clamp is structurally similar to the trimeric...; Region: beta_clamp; cd00140
553482000015	putative DNA binding surface [nucleotide binding]; other site
553482000016	dimer interface [polypeptide binding]; other site
553482000017	beta-clamp/clamp loader binding surface; other site
553482000018	beta-clamp/translesion DNA polymerase binding surface; other site
553482000019	HMMPfam hit to PF00712, DNA polymerase III beta subunit, N-te, score 1.9e-25
553482000020	HMMPfam hit to PF02767, DNA polymerase III beta subunit, cent, score 8e-32
553482000021	HMMPfam hit to PF02768, DNA polymerase III beta subunit, C-te, score 2.9e-30
553482000022	Bacterial protein of unknown function (DUF951); Region: DUF951; pfam06107
553482000023	HMMPfam hit to PF06107, Bacterial protein of unknown function (DUF95, score 1.5e-44
553482000024	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
553482000025	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
553482000026	non-specific DNA binding site [nucleotide binding]; other site
553482000027	salt bridge; other site
553482000028	sequence-specific DNA binding site [nucleotide binding]; other site
553482000029	HMMPfam hit to PF01381, Helix-turn-helix, score 2.8e-18
553482000030	Predicted helix-turn-helix motif with score 2169.000, SD 6.57 at aa 17-38, sequence LSQDALAEKLFISRQAISKWEN
553482000031	1 transmembrane helix predicted for SEQ0004 by TMHMM2.0 at aa 99-117
553482000032	GTP-binding protein YchF; Reviewed; Region: PRK09601
553482000033	YchF GTPase; Region: YchF; cd01900
553482000034	G1 box; other site
553482000035	GTP/Mg2+ binding site [chemical binding]; other site
553482000036	Switch I region; other site
553482000037	G2 box; other site
553482000038	Switch II region; other site
553482000039	G3 box; other site
553482000040	G4 box; other site
553482000041	G5 box; other site
553482000042	TGS_YchF_C: This subfamily represents TGS domain-containing YchF GTP-binding protein, a universally conserved GTPase whose function is unknown. The N-terminal domain of the YchF protein belongs to the Obg-like family of GTPases, and some members of the...; Region: TGS_YchF_C; cd04867
553482000043	HMMPfam hit to PF01926, GTPase of unknown function, score 7.1e-35
553482000044	PS00017 ATP/GTP-binding site motif A (P-loop).
553482000045	HMMPfam hit to PF06071, Protein of unknown function (DUF933), score 2.9e-61
553482000046	Peptidyl-tRNA hydrolase (PTH) is a monomeric protein that cleaves the ester bond linking the nascent peptide and tRNA when peptidyl-tRNA is released prematurely from the ribosome. This ensures the recycling of peptidyl-tRNAs into tRNAs produced through...; Region: PTH; cd00462
553482000047	putative active site [active]
553482000048	catalytic residue [active]
553482000049	HMMPfam hit to PF01195, Peptidyl-tRNA hydrolase, score 4.3e-81
553482000050	PS01196 Peptidyl-tRNA hydrolase signature 2.
553482000051	Transcription-repair coupling factor (superfamily II helicase) [DNA replication, recombination, and repair / Transcription]; Region: Mfd; COG1197
553482000052	CarD-like/TRCF domain; Region: CarD_TRCF; smart01058
553482000053	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
553482000054	ATP binding site [chemical binding]; other site
553482000055	putative Mg++ binding site [ion binding]; other site
553482000056	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
553482000057	nucleotide binding region [chemical binding]; other site
553482000058	ATP-binding site [chemical binding]; other site
553482000059	This domain is found in proteins necessary for strand-specific repair in DNA such as TRCF in Escherichia coli; Region: TRCF; smart00982
553482000060	HMMPfam hit to PF02559, CarD-like/TRCF domain, score 1e-50
553482000061	HMMPfam hit to PF04851, Type III restriction enzyme, res subunit, score 4.4e-06
553482000062	HMMPfam hit to PF00270, DEAD/DEAH box helicase, score 1.1e-40
553482000063	PS00017 ATP/GTP-binding site motif A (P-loop).
553482000064	HMMPfam hit to PF00271, Helicase conserved C-terminal domain, score 8.4e-19
553482000065	HMMPfam hit to PF03461, TRCF domain, score 6.1e-35
553482000066	Membrane protein involved in the export of O-antigen and teichoic acid [General function prediction only]; Region: RfbX; COG2244
553482000067	Multidrug and toxic compound extrusion family and similar proteins; Region: MATE_like; cl09326
553482000068	HMMPfam hit to PF01943, Polysaccharide biosynthesis protein, score 1e-05
553482000069	14 transmembrane helices predicted for SEQ0008 by TMHMM2.0 at aa 17-37, 52-74, 81-103, 118-140, 159-181, 185-202, 223-245, 281-303, 315-337, 347-369, 382-404, 409-426, 433-455 and 460-482
553482000070	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482000071	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
553482000072	RNA binding surface [nucleotide binding]; other site
553482000073	HMMPfam hit to PF01479, S4 domain, score 2.3e-10
553482000074	Septum formation initiator [Cell division and chromosome partitioning]; Region: COG2919
553482000075	Septum formation initiator; Region: DivIC; pfam04977
553482000076	1 transmembrane helix predicted for SEQ0010 by TMHMM2.0 at aa 37-54
553482000077	HMMPfam hit to PF04977, Septum formation initiator, score 2.2e-21
553482000078	SH3-like domain; Region: SH3_8; pfam13457
553482000079	Beta-lactamase enzyme family; Region: Beta-lactamase2; pfam13354
553482000080	PS00017 ATP/GTP-binding site motif A (P-loop).
553482000081	tRNA(Ile)-lysidine synthase MesJ [Cell cycle control, cell division, chromosome partitioning]; Region: MesJ; COG0037
553482000082	N-terminal domain of predicted ATPase of the PP-loop faimly implicated in cell cycle control [Cell division and chromosome partitioning]. This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases...; Region: PP-ATPase; cd01992
553482000083	Ligand Binding Site [chemical binding]; other site
553482000084	TilS substrate C-terminal domain; Region: TilS_C; smart00977
553482000085	HMMPfam hit to PF01171, PP-loop family, score 7e-85
553482000086	1 transmembrane helix predicted for SEQ0013 by TMHMM2.0 at aa 21-43
553482000087	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
553482000088	active site
553482000089	HMMPfam hit to PF00156, Phosphoribosyl transferase domain, score 2.2e-33
553482000090	ATP-dependent Zn proteases [Posttranslational modification, protein turnover, chaperones]; Region: HflB; COG0465
553482000091	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
553482000092	Walker A motif; other site
553482000093	ATP binding site [chemical binding]; other site
553482000094	Walker B motif; other site
553482000095	arginine finger; other site
553482000096	Peptidase family M41; Region: Peptidase_M41; pfam01434
553482000097	2 transmembrane helices predicted for SEQ0015 by TMHMM2.0 at aa 13-31 and 134-156
553482000098	HMMPfam hit to PF06480, FtsH Extracellular, score 1.1e-35
553482000099	HMMPfam hit to PF00004, ATPase family associated with various c, score 1.4e-91
553482000100	PS00017 ATP/GTP-binding site motif A (P-loop).
553482000101	PS00674 AAA-protein family signature.
553482000102	HMMPfam hit to PF01434, Peptidase family M41, score 2e-108
553482000103	amino acid transporter; Region: 2A0306; TIGR00909
553482000104	C-terminus of AA_permease; Region: AA_permease_C; pfam13906
553482000105	HMMPfam hit to PF00324, Amino acid permease, score 1.3e-25
553482000106	12 transmembrane helices predicted for SEQ0016 by TMHMM2.0 at aa 48-70, 74-96, 108-130, 171-193, 200-222, 237-259, 280-302, 331-353, 374-396, 401-418, 431-453 and 457-479
553482000107	PS00017 ATP/GTP-binding site motif A (P-loop).
553482000108	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482000109	rod shape-determining protein MreC; Provisional; Region: PRK13922
553482000110	rod shape-determining protein MreC; Region: MreC; pfam04085
553482000111	1 transmembrane helix predicted for SEQ0017 by TMHMM2.0 at aa 9-31
553482000112	HMMPfam hit to PF04085, rod shape-determining protein MreC, score 2.2e-23
553482000113	6 transmembrane helices predicted for SEQ0018 by TMHMM2.0 at aa 7-29, 33-52, 57-74, 78-100, 107-126 and 136-158
553482000114	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3883
553482000115	Surface antigen [General function prediction only]; Region: COG3942
553482000116	CHAP domain; Region: CHAP; pfam05257
553482000117	HMMPfam hit to PF05257, CHAP domain, score 2.7e-38
553482000118	ribose-phosphate pyrophosphokinase; Provisional; Region: PRK02269
553482000119	N-terminal domain of ribose phosphate pyrophosphokinase; Region: Pribosyltran_N; pfam13793
553482000120	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
553482000121	active site
553482000122	PS00339 Aminoacyl-transfer RNA synthetases class-II signature 2.
553482000123	PS00114 Phosphoribosyl pyrophosphate synthetase signature.
553482000124	HMMPfam hit to PF00156, Phosphoribosyl transferase domain, score 7.8e-35
553482000125	PS00103 Purine/pyrimidine phosphoribosyl transferases signature.
553482000126	Recombination protein O N terminal; Region: RecO_N; pfam11967
553482000127	DNA repair protein RecO; Region: reco; TIGR00613
553482000128	Recombination protein O C terminal; Region: RecO_C; pfam02565
553482000129	HMMPfam hit to PF02565, Recombination protein O, score 2.4e-15
553482000130	PS00190 Cytochrome c family heme-binding site signature.
553482000131	putative phosphate acyltransferase; Provisional; Region: PRK05331
553482000132	HMMPfam hit to PF02504, Fatty acid synthesis protein, score 7.8e-129
553482000133	acyl carrier protein; Provisional; Region: PRK12449
553482000134	HMMPfam hit to PF00550, Phosphopantetheine attachment site, score 1.6e-06
553482000135	phosphoribosylaminoimidazole-succinocarboxamide synthase; Reviewed; Region: PRK09362
553482000136	bacterial and archaeal 5-aminoimidazole-4-(N-succinylcarboxamide) ribonucleotide (SAICAR) synthase; Region: SAICAR_synt_PurC; cd01415
553482000137	ATP binding site [chemical binding]; other site
553482000138	active site
553482000139	substrate binding site [chemical binding]; other site
553482000140	HMMPfam hit to PF01259, SAICAR synthetase, score 3.2e-106
553482000141	PS01057 SAICAR synthetase signature 1.
553482000142	PS01058 SAICAR synthetase signature 2.
553482000143	phosphoribosylformylglycinamidine synthase, clade II; Region: FGAM-synthase; TIGR01857
553482000144	AIR (aminoimidazole ribonucleotide) synthase related protein. This family includes Hydrogen expression/formation protein HypE, AIR synthases, FGAM (formylglycinamidine ribonucleotide) synthase and Selenophosphate synthetase (SelD). The N-terminal domain...; Region: PurM-like; cl10019
553482000145	PurL subunit of the formylglycinamide ribonucleotide amidotransferase (FGAR-AT), first repeat. FGAR-AT catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to formylglycinamidine ribonucleotide (FGAM), ADP; Region: PurL_repeat1; cd02203
553482000146	dimerization interface [polypeptide binding]; other site
553482000147	ATP binding site [chemical binding]; other site
553482000148	PurL subunit of the formylglycinamide ribonucleotide amidotransferase (FGAR-AT), second repeat. FGAR-AT catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to formylglycinamidine ribonucleotide (FGAM), ADP; Region: PurL_repeat2; cd02204
553482000149	dimerization interface [polypeptide binding]; other site
553482000150	ATP binding site [chemical binding]; other site
553482000151	Type 1 glutamine amidotransferase (GATase1)-like domain found in Formylglycinamide ribonucleotide amidotransferase; Region: GATase1_FGAR_AT; cd01740
553482000152	putative active site [active]
553482000153	catalytic triad [active]
553482000154	1 transmembrane helix predicted for SEQ0026 by TMHMM2.0 at aa 7-29
553482000155	HMMPfam hit to PF02769, AIR synthase related protein, C-terminal dom, score 1e-31
553482000156	PS01159 WW/rsp5/WWP domain signature.
553482000157	amidophosphoribosyltransferase; Provisional; Region: PRK07272
553482000158	Glutamine amidotransferases class-II (GN-AT)_GPAT- type. This domain is found at the N-terminus of  glutamine phosphoribosylpyrophosphate (Prpp) amidotransferase (GPATase) . The glutaminase domain catalyzes amide nitrogen transfer from glutamine to the...; Region: GPATase_N; cd00715
553482000159	active site
553482000160	tetramer interface [polypeptide binding]; other site
553482000161	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
553482000162	active site
553482000163	PS00443 Glutamine amidotransferases class-II active site.
553482000164	HMMPfam hit to PF00310, Glutamine amidotransferases class-II, score 4.1e-36
553482000165	HMMPfam hit to PF00156, Phosphoribosyl transferase domain, score 2.4e-10
553482000166	PS00103 Purine/pyrimidine phosphoribosyl transferases signature.
553482000167	phosphoribosylaminoimidazole synthetase; Provisional; Region: PRK05385
553482000168	PurM (Aminoimidazole Ribonucleotide [AIR] synthetase), one of eleven enzymes required for purine biosynthesis, catalyzes the conversion of formylglycinamide ribonucleotide (FGAM) and ATP to AIR, ADP, and Pi, the fifth step in de novo purine biosynthesis; Region: PurM; cd02196
553482000169	dimerization interface [polypeptide binding]; other site
553482000170	putative ATP binding site [chemical binding]; other site
553482000171	HMMPfam hit to PF00586, AIR synthase related protein, N-terminal dom, score 1.2e-70
553482000172	HMMPfam hit to PF02769, AIR synthase related protein, C-terminal dom, score 1.1e-43
553482000173	phosphoribosylglycinamide formyltransferase; Reviewed; Region: purN; PRK05647
553482000174	Phosphoribosylglycinamide formyltransferase (GAR transformylase, GART); Region: FMT_core_GART; cd08645
553482000175	active site
553482000176	substrate binding site [chemical binding]; other site
553482000177	cosubstrate binding site; other site
553482000178	catalytic site [active]
553482000179	HMMPfam hit to PF00551, Formyl transferase, score 1.6e-55
553482000180	bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; Provisional; Region: purH; PRK00881
553482000181	Inosine monophosphate cyclohydrolase domain. This is the N-terminal domain in the purine biosynthesis pathway protein ATIC (purH). The bifunctional ATIC protein contains a C-terminal  ATIC formylase domain that formylates...; Region: IMPCH; cd01421
553482000182	purine monophosphate binding site [chemical binding]; other site
553482000183	dimer interface [polypeptide binding]; other site
553482000184	putative catalytic residues [active]
553482000185	AICARFT/IMPCHase bienzyme; Region: AICARFT_IMPCHas; smart00798
553482000186	AICARFT/IMPCHase bienzyme; Region: AICARFT_IMPCHas; cl03362
553482000187	HMMPfam hit to PF02142, MGS-like domain, score 9.1e-52
553482000188	HMMPfam hit to PF01808, AICARFT/IMPCHase bienzyme, score 2.2e-143
553482000189	Surface antigen [General function prediction only]; Region: COG3942
553482000190	CHAP domain; Region: CHAP; pfam05257
553482000191	Bacterial SH3 domain; Region: SH3_5; pfam08460
553482000192	HMMPfam hit to PF08460, Bacterial SH3 domain, score 8.9e-21
553482000193	HMMPfam hit to PF05257, CHAP domain, score 7.9e-29
553482000194	phosphoribosylamine--glycine ligase; Provisional; Region: PRK00885
553482000195	Phosphoribosylglycinamide synthetase, N domain; Region: GARS_N; pfam02844
553482000196	Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Region: GARS_A; pfam01071
553482000197	Phosphoribosylglycinamide synthetase, C domain; Region: GARS_C; pfam02843
553482000198	HMMPfam hit to PF02844, Phosphoribosylglycinamide synthetase, N d, score 1.4e-41
553482000199	HMMPfam hit to PF01071, Phosphoribosylglycinamide synthetase, ATP, score 1.7e-119
553482000200	HMMPfam hit to PF08442, ATP-grasp domain, score 0.0042
553482000201	HMMPfam hit to PF02655, ATP-grasp domain, score 0.0011
553482000202	PS00184 Phosphoribosylglycinamide synthetase signature.
553482000203	HMMPfam hit to PF02843, Phosphoribosylglycinamide synthetase, C d, score 1.9e-13
553482000204	Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase [Nucleotide transport and metabolism]; Region: PurE; COG0041
553482000205	HMMPfam hit to PF00731, AIR carboxylase, score 7.4e-90
553482000206	phosphoribosylaminoimidazole carboxylase ATPase subunit; Reviewed; Region: PRK06019
553482000207	ATP-grasp domain; Region: ATP-grasp; pfam02222
553482000208	HMMPfam hit to PF02222, ATP-grasp domain, score 7e-64
553482000209	HMMPfam hit to PF02655, ATP-grasp domain, score 0.00061
553482000210	gene remnant. Similar to the N-terminal region of Streptococcus agalactiae hypothetical protein UniProt:Q3D9U7 (EMBL:AAJR01000013 (317 aa) fasta scores: E()=0.0018, 66.667% id in 30 aa. Downstream CDS, SEQ0036a is similar to an internal region of the same protein.
553482000211	gene remnant. Upstream CDS, SEQ0036 is similar to the N-terminus of the same protein. Similar to an internal region of Streptococcus agalactiae COH1 hypothetical protein UniProt:Q3D9U7 (EMBL:AAJR01000013 (317 aa) fasta scores: E()=6.7, 35.484% id in 31 aa
553482000212	adenylosuccinate lyase; Provisional; Region: PRK07492
553482000213	Adenylsuccinate lyase (ASL)_subgroup 1; Region: Adenylsuccinate_lyase_1; cd01360
553482000214	tetramer interface [polypeptide binding]; other site
553482000215	active site
553482000216	HMMPfam hit to PF00206, Lyase, score 8.8e-92
553482000217	PS00163 Fumarate lyases signature.
553482000218	CDS contains a frameshift after codon 77. Similar to Streptococcus pyogenes serotype M3 transcriptional regulator UniProt:Q1JP26 (EMBL:CP000259 (303 aa) fasta scores: E()=1.4e-83, 74.257% id in 303 aa
553482000219	HMMPfam hit to PF01381, Helix-turn-helix, score 6.2e-07
553482000220	Holliday junction DNA helicase RuvB; Reviewed; Region: ruvB; PRK00080
553482000221	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
553482000222	Walker A motif; other site
553482000223	ATP binding site [chemical binding]; other site
553482000224	Walker B motif; other site
553482000225	arginine finger; other site
553482000226	Holliday junction DNA helicase ruvB C-terminus; Region: RuvB_C; pfam05491
553482000227	HMMPfam hit to PF05496, Holliday junction DNA helicase ruvB N-termin, score 2.4e-26
553482000228	HMMPfam hit to PF00004, ATPase family associated with various cellul, score 1.3e-26
553482000229	HMMPfam hit to PF07728, ATPase family associated with various cellul, score 0.0002
553482000230	PS00017 ATP/GTP-binding site motif A (P-loop).
553482000231	HMMPfam hit to PF05491, Holliday junction DNA helicase ruvB C-termin, score 1.5e-52
553482000232	Protein-tyrosine-phosphatase [Signal transduction mechanisms]; Region: Wzb; COG0394
553482000233	Low molecular weight phosphatase family; Region: LMWPc; cd00115
553482000234	active site
553482000235	HMMPfam hit to PF01451, Low molecular weight phosphotyrosine protein, score 3.7e-33
553482000236	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4642
553482000237	1 transmembrane helix predicted for SEQ0042 by TMHMM2.0 at aa 20-39
553482000238	HMMPfam hit to PF02493, MORN repeat, score 3.5e-05
553482000239	HMMPfam hit to PF02493, MORN repeat, score 0.001
553482000240	HMMPfam hit to PF02493, MORN repeat, score 0.00052
553482000241	Predicted acyltransferases [Lipid metabolism]; Region: COG1835
553482000242	glucans biosynthesis protein; Provisional; Region: opgC; PRK03854
553482000243	yrhL-like subfamily of SGNH-hydrolases, a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely...; Region: SGNH_hydrolase_yrhL_like; cd01840
553482000244	catalytic triad [active]
553482000245	catalytic triad [active]
553482000246	oxyanion hole [active]
553482000247	HMMPfam hit to PF01757, Acyltransferase family, score 7.1e-31
553482000248	11 transmembrane helices predicted for SEQ0043 by TMHMM2.0 at aa 5-23, 27-49, 69-90, 131-153, 166-188, 192-214, 235-257, 261-283, 295-317, 327-349 and 370-392
553482000249	bifunctional acetaldehyde-CoA/alcohol dehydrogenase; Provisional; Region: PRK13805
553482000250	Coenzyme A acylating aldehyde dehydrogenase (ACDH), ALDH family 20-like; Region: ALDH_F20_ACDH; cd07122
553482000251	putative catalytic cysteine [active]
553482000252	C-terminal alcohol dehydrogenase domain of the acetaldehyde dehydrogenase-alcohol dehydrogenase bifunctional two-domain protein (AAD); Region: AAD_C; cd08178
553482000253	putative active site [active]
553482000254	metal binding site [ion binding]; metal-binding site
553482000255	HMMPfam hit to PF00171, Aldehyde dehydrogenase family, score 3.4e-07
553482000256	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482000257	HMMPfam hit to PF00465, Iron-containing alcohol dehydrogenase, score 1.3e-142
553482000258	PS00913 Iron-containing alcohol dehydrogenases signature 1.
553482000259	PS00060 Iron-containing alcohol dehydrogenases signature 2.
553482000260	formaldehyde dehydrogenase (FDH)-like; Region: FDH_like_ADH2; cd08286
553482000261	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
553482000262	catalytic Zn binding site [ion binding]; other site
553482000263	structural Zn binding site [ion binding]; other site
553482000264	NAD(P) binding site [chemical binding]; other site
553482000265	HMMPfam hit to PF08240, Alcohol dehydrogenase GroES-like domain, score 2.4e-37
553482000266	PS00059 Zinc-containing alcohol dehydrogenases signature.
553482000267	HMMPfam hit to PF00107, Zinc-binding dehydrogenase, score 8.7e-36
553482000268	ethanol-active dehydrogenase/acetaldehyde-active reductase; Provisional; Region: PRK09422
553482000269	Cinnamyl alcohol dehydrogenases (CAD); Region: CAD3; cd08297
553482000270	NAD binding site [chemical binding]; other site
553482000271	substrate binding site [chemical binding]; other site
553482000272	catalytic Zn binding site [ion binding]; other site
553482000273	tetramer interface [polypeptide binding]; other site
553482000274	structural Zn binding site [ion binding]; other site
553482000275	HMMPfam hit to PF08240, Alcohol dehydrogenase GroES-like domain, score 9.5e-49
553482000276	PS00190 Cytochrome c family heme-binding site signature.
553482000277	PS00059 Zinc-containing alcohol dehydrogenases signature.
553482000278	HMMPfam hit to PF00107, Zinc-binding dehydrogenase, score 1.2e-39
553482000279	genomic island
553482000280	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
553482000281	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
553482000282	ATP-binding cassette domain of multidrug resistance protein-like transporters; Region: ABCC_MRP_Like; cd03228
553482000283	Walker A/P-loop; other site
553482000284	ATP binding site [chemical binding]; other site
553482000285	Q-loop/lid; other site
553482000286	ABC transporter signature motif; other site
553482000287	Walker B; other site
553482000288	D-loop; other site
553482000289	H-loop/switch region; other site
553482000290	HMMPfam hit to PF00664, ABC transporter transmembrane region, score 1.1e-05
553482000291	5 transmembrane helices predicted for SEQ0047 by TMHMM2.0 at aa 12-34, 49-71, 124-146, 150-169 and 235-257
553482000292	HMMPfam hit to PF00005, ABC transporter, score 4.6e-27
553482000293	PS00017 ATP/GTP-binding site motif A (P-loop).
553482000294	CDS contains a frameshift after codon 214. Similar to Enterococcus faecalis (Streptococcus faecalis) HesA/MoeB/ThiF family protein UniProt:Q835P7 (EMBL:AE016830 (377 aa) fasta scores: E()=8.8e-21, 28.609% id in 381 aa
553482000295	HMMPfam hit to PF00899, ThiF family, score 1.3e-08
553482000296	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
553482000297	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
553482000298	HMMPfam hit to PF00675, Insulinase (Peptidase family M16), score 0.00016
553482000299	PS00143 Insulinase family, zinc-binding region signature.
553482000300	HMMPfam hit to PF05193, Peptidase M16 inactive domain, score 0.00018
553482000301	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
553482000302	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
553482000303	non-specific DNA binding site [nucleotide binding]; other site
553482000304	salt bridge; other site
553482000305	sequence-specific DNA binding site [nucleotide binding]; other site
553482000306	transcriptional activator, Rgg/GadR/MutR family, C-terminal domain; Region: RGG_Cterm; TIGR01716
553482000307	HMMPfam hit to PF01381, Helix-turn-helix, score 2.2e-05
553482000308	Threonine synthase [Amino acid transport and metabolism]; Region: ThrC; COG0498
553482000309	Threonine synthase catalyzes the final step of threonine biosynthesis. The conversion of O-phosphohomoserine into threonine and inorganic phosphate is pyridoxal 5'-phosphate dependent. The Thr-synth_1 CD includes members from higher plants; Region: Thr-synth_2; cd01560
553482000310	pyridoxal 5'-phosphate binding site [chemical binding]; other site
553482000311	catalytic residue [active]
553482000312	HMMPfam hit to PF00291, Pyridoxal-phosphate dependent enzyme, score 3.8e-08
553482000313	PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site.
553482000314	Na+-driven multidrug efflux pump [Defense mechanisms]; Region: NorM; COG0534
553482000315	Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Thermotoga marina NorM; Region: MATE_NorM_like; cd13137
553482000316	HMMPfam hit to PF01554, MatE, score 9e-21
553482000317	9 transmembrane helices predicted for SEQ0053 by TMHMM2.0 at aa 27-49, 53-75, 87-109, 129-151, 163-182, 186-208, 306-328, 343-365 and 387-409
553482000318	HMMPfam hit to PF01554, MatE, score 1.3e-27
553482000319	30S ribosomal protein S10; Reviewed; Region: rpsJ; PRK00596
553482000320	HMMPfam hit to PF00338, Ribosomal protein S10p/S20e, score 7.5e-60
553482000321	PS00361 Ribosomal protein S10 signature.
553482000322	50S ribosomal protein L3; Validated; Region: rplC; PRK00001
553482000323	HMMPfam hit to PF00297, Ribosomal protein L3, score 1.7e-92
553482000324	PS00474 Ribosomal protein L3 signature.
553482000325	50S ribosomal protein L4; Provisional; Region: rplD; PRK05319
553482000326	HMMPfam hit to PF00573, Ribosomal protein L4/L1 family, score 2.4e-72
553482000327	50S ribosomal protein L23; Reviewed; Region: rplW; PRK05738
553482000328	HMMPfam hit to PF00276, Ribosomal protein L23, score 3.1e-32
553482000329	PS00050 Ribosomal protein L23 signature.
553482000330	50S ribosomal protein L2; Validated; Region: rplB; PRK09374
553482000331	Ribosomal Proteins L2, RNA binding domain; Region: Ribosomal_L2; pfam00181
553482000332	Ribosomal Proteins L2, C-terminal domain; Region: Ribosomal_L2_C; pfam03947
553482000333	HMMPfam hit to PF00181, Ribosomal Proteins L2, RNA binding dom, score 8e-48
553482000334	HMMPfam hit to PF03947, Ribosomal Proteins L2, C-terminal doma, score 8.8e-87
553482000335	PS00467 Ribosomal protein L2 signature.
553482000336	30S ribosomal protein S19; Reviewed; Region: rpsS; PRK00357
553482000337	HMMPfam hit to PF00203, Ribosomal protein S19, score 3.1e-51
553482000338	PS00323 Ribosomal protein S19 signature.
553482000339	Ribosomal protein L22/L17e.  L22 (L17 in eukaryotes) is a core protein of the large ribosomal subunit.  It is the only ribosomal protein that interacts with all six domains of 23S rRNA, and is one of the proteins important for directing the proper...; Region: Ribosomal_L22; cd00336
553482000340	putative translocon binding site; other site
553482000341	protein-rRNA interface [nucleotide binding]; other site
553482000342	HMMPfam hit to PF00237, Ribosomal protein L22p/L17e, score 2.3e-60
553482000343	PS00464 Ribosomal protein L22 signature.
553482000344	30S ribosomal protein S3; Reviewed; Region: rpsC; PRK00310
553482000345	K homology RNA-binding (KH) domain of the prokaryotic 30S small ribosomal subunit protein S3. S3  is part of the head region of the 30S ribosomal subunit and is believed to interact with mRNA as it threads its way from the latch into the channel.  The KH...; Region: 30S_S3_KH; cd02412
553482000346	G-X-X-G motif; other site
553482000347	Ribosomal protein S3, C-terminal domain; Region: Ribosomal_S3_C; pfam00189
553482000348	HMMPfam hit to PF00417, Ribosomal protein S3, N-terminal domai, score 4.9e-29
553482000349	HMMPfam hit to PF07650, KH domain, score 4.8e-23
553482000350	HMMPfam hit to PF00189, Ribosomal protein S3, C-terminal domai, score 1.4e-50
553482000351	PS00548 Ribosomal protein S3 signature.
553482000352	Ribosomal_L16_L10e: L16 is an essential protein in the large ribosomal subunit of bacteria, mitochondria, and chloroplasts. Large subunits that lack L16 are defective in peptidyl transferase activity, peptidyl-tRNA hydrolysis activity, association with...; Region: Ribosomal_L16_L10e; cd01433
553482000353	23S rRNA interface [nucleotide binding]; other site
553482000354	5S rRNA interface [nucleotide binding]; other site
553482000355	putative antibiotic binding site [chemical binding]; other site
553482000356	L25 interface [polypeptide binding]; other site
553482000357	L27 interface [polypeptide binding]; other site
553482000358	HMMPfam hit to PF00252, Ribosomal protein L16, score 1.2e-82
553482000359	PS00586 Ribosomal protein L16 signature 1.
553482000360	PS00701 Ribosomal protein L16 signature 2.
553482000361	Ribosomal L29 protein/HIP.  L29 is a protein of the large ribosomal Subunit. A homolog, called heparin/heparan sulfate interacting protein (HIP), has also been identified in mammals.  L29 is located on the surface of the large ribosomal subunit, where it...; Region: Ribosomal_L29_HIP; cd00427
553482000362	23S rRNA interface [nucleotide binding]; other site
553482000363	putative translocon interaction site; other site
553482000364	signal recognition particle (SRP54) interaction site; other site
553482000365	L23 interface [polypeptide binding]; other site
553482000366	trigger factor interaction site; other site
553482000367	HMMPfam hit to PF00831, Ribosomal L29 protein, score 2.1e-28
553482000368	30S ribosomal protein S17; Reviewed; Region: rpsQ; PRK05610
553482000369	HMMPfam hit to PF00366, Ribosomal protein S17, score 1.6e-36
553482000370	PS00056 Ribosomal protein S17 signature.
553482000371	50S ribosomal protein L14; Validated; Region: rplN; PRK05483
553482000372	PS00049 Ribosomal protein L14 signature.
553482000373	50S ribosomal protein L24; Reviewed; Region: rplX; PRK00004
553482000374	KOW motif of Ribosomal Protein L26; Region: KOW_RPL26; cd06089
553482000375	RNA binding site [nucleotide binding]; other site
553482000376	HMMPfam hit to PF00467, KOW motif, score 6.6e-09
553482000377	PS01108 Ribosomal protein L24 signature.
553482000378	50S ribosomal protein L5; Validated; Region: rplE; PRK00010
553482000379	Ribosomal protein L5; Region: Ribosomal_L5; pfam00281
553482000380	ribosomal L5P family C-terminus; Region: Ribosomal_L5_C; pfam00673
553482000381	HMMPfam hit to PF00281, Ribosomal protein L5, score 7.2e-30
553482000382	PS00358 Ribosomal protein L5 signature.
553482000383	HMMPfam hit to PF00673, ribosomal L5P family C-terminus, score 5.9e-53
553482000384	30S ribosomal protein S14; Reviewed; Region: rpsN; PRK08061
553482000385	HMMPfam hit to PF00253, Ribosomal protein S14p/S29e, score 9.7e-20
553482000386	PS00527 Ribosomal protein S14 signature.
553482000387	30S ribosomal protein S8; Validated; Region: rpsH; PRK00136
553482000388	HMMPfam hit to PF00410, Ribosomal protein S8, score 4.8e-76
553482000389	PS00053 Ribosomal protein S8 signature.
553482000390	50S ribosomal protein L6; Validated; Region: rplF; PRK05498
553482000391	Ribosomal protein L6; Region: Ribosomal_L6; pfam00347
553482000392	Ribosomal protein L6; Region: Ribosomal_L6; pfam00347
553482000393	HMMPfam hit to PF00347, Ribosomal protein L6, score 1.5e-24
553482000394	HMMPfam hit to PF00347, Ribosomal protein L6, score 2.2e-30
553482000395	PS00525 Ribosomal protein L6 signature 1.
553482000396	Ribosomal L18/L5e:  L18 (L5e) is a ribosomal protein found in the central protuberance (CP) of the large subunit. L18 binds 5S rRNA and induces a conformational change that stimulates the binding of L5 to 5S rRNA. Association of 5S rRNA with 23S rRNA...; Region: Ribosomal_L18_L5e; cd00432
553482000397	5S rRNA interface [nucleotide binding]; other site
553482000398	L27 interface [polypeptide binding]; other site
553482000399	23S rRNA interface [nucleotide binding]; other site
553482000400	L5 interface [polypeptide binding]; other site
553482000401	HMMPfam hit to PF00861, Ribosomal L18p/L5e family, score 7.2e-56
553482000402	30S ribosomal protein S5; Validated; Region: rpsE; PRK00550
553482000403	Ribosomal protein S5, N-terminal domain; Region: Ribosomal_S5; pfam00333
553482000404	Ribosomal protein S5, C-terminal domain; Region: Ribosomal_S5_C; pfam03719
553482000405	HMMPfam hit to PF00333, Ribosomal protein S5, N-terminal domai, score 1.3e-42
553482000406	PS00585 Ribosomal protein S5 signature.
553482000407	PS00589 PTS HPR component serine phosphorylation site signature.
553482000408	HMMPfam hit to PF03719, Ribosomal protein S5, C-terminal domai, score 6.2e-35
553482000409	Ribosomal protein L30, which is found in eukaryotes and prokaryotes but not in archaea, is one of the smallest ribosomal proteins with a molecular mass of about 7kDa. L30 binds the 23SrRNA as well as the 5S rRNA and is one of five ribosomal proteins that...; Region: Ribosomal_L30; cd01658
553482000410	23S rRNA binding site [nucleotide binding]; other site
553482000411	HMMPfam hit to PF00327, Ribosomal protein L30p/L7e, score 2.8e-14
553482000412	PS00634 Ribosomal protein L30 signature.
553482000413	50S ribosomal protein L15; Reviewed; Region: rplO; PRK05592
553482000414	HMMPfam hit to PF01305, Ribosomal protein L15 amino terminal re, score 5.3e-59
553482000415	HMMPfam hit to PF00256, Ribosomal protein L15, score 3.1e-11
553482000416	PS00475 Ribosomal protein L15 signature.
553482000417	preprotein translocase subunit SecY; Reviewed; Region: secY; PRK09204
553482000418	SecY translocase; Region: SecY; pfam00344
553482000419	10 transmembrane helices predicted for SEQ0075 by TMHMM2.0 at aa 20-42, 66-88, 117-139, 149-168, 175-197, 212-234, 267-289, 304-326, 368-390 and 395-414
553482000420	HMMPfam hit to PF00344, eubacterial secY protein, score 5.7e-167
553482000421	PS00755 Protein secY signature 1.
553482000422	PS00756 Protein secY signature 2.
553482000423	PS00095 C-5 cytosine-specific DNA methylases C-terminal signature.
553482000424	adenylate kinase; Reviewed; Region: adk; PRK00279
553482000425	Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine triphosphates (ATP) to adenosine monophosphates (AMP) and to yield adenosine diphosphates (ADP). This enzyme is required for the biosynthesis of ADP and is essential for...; Region: ADK; cd01428
553482000426	AMP-binding site [chemical binding]; other site
553482000427	ATP-AMP (Ap5A)-binding site [chemical binding]; other site
553482000428	HMMPfam hit to PF00406, Adenylate kinase, score 2e-86
553482000429	PS00113 Adenylate kinase signature.
553482000430	S1_IF1: Translation Initiation Factor IF1, S1-like RNA-binding domain. IF1 contains an S1-like RNA-binding domain, which is found in a wide variety of RNA-associated proteins. Translation initiation includes a number of interrelated steps preceding the...; Region: S1_IF1; cd04451
553482000431	rRNA binding site [nucleotide binding]; other site
553482000432	predicted 30S ribosome binding site; other site
553482000433	HMMPfam hit to PF00575, S1 RNA binding domain, score 3.2e-13
553482000434	HMMPfam hit to PF01176, Translation initiation factor 1A / IF-1, score 1.5e-35
553482000435	Ribosomal protein L36; Region: Ribosomal_L36; pfam00444
553482000436	PS00828 Ribosomal protein L36 signature.
553482000437	Ribosomal protein S13 [Translation, ribosomal structure and biogenesis]; Region: RpsM; COG0099
553482000438	30S ribosomal protein S13; Region: bact_S13; TIGR03631
553482000439	HMMPfam hit to PF00416, Ribosomal protein S13/S18, score 5.3e-55
553482000440	PS00646 Ribosomal protein S13 signature.
553482000441	30S ribosomal protein S11; Validated; Region: PRK05309
553482000442	HMMPfam hit to PF00411, Ribosomal protein S11, score 2.1e-72
553482000443	PS00054 Ribosomal protein S11 signature.
553482000444	DNA-directed RNA polymerase subunit alpha; Provisional; Region: PRK05182
553482000445	N-terminal domain of the Alpha subunit of Bacterial RNA polymerase; Region: RNAP_alpha_NTD; cd06928
553482000446	alphaNTD homodimer interface [polypeptide binding]; other site
553482000447	alphaNTD - beta interaction site [polypeptide binding]; other site
553482000448	alphaNTD - beta' interaction site [polypeptide binding]; other site
553482000449	Bacterial RNA polymerase, alpha chain C terminal domain; Region: RNA_pol_A_CTD; pfam03118
553482000450	HMMPfam hit to PF01193, RNA polymerase Rpb3/Rpb11 dimerisation, score 6e-26
553482000451	HMMPfam hit to PF01000, RNA polymerase Rpb3/RpoA insert domain, score 1.5e-55
553482000452	HMMPfam hit to PF03118, Bacterial RNA polymerase, alpha chain C, score 1.3e-31
553482000453	50S ribosomal protein L17; Validated; Region: rplQ; PRK05591
553482000454	HMMPfam hit to PF01196, Ribosomal protein L17, score 1.7e-62
553482000455	PS01167 Ribosomal protein L17 signature.
553482000456	Similar to the C-terminal region of Streptococcus mutans transposase UniProt:Q8DTK6 (EMBL:AE014133 (46 aa) blastp scores: E()=5e-04
553482000457	CDS contains a nonsense mutation (amber) after codon 115
553482000458	2 transmembrane helices predicted for SEQ0085 by TMHMM2.0 at aa 43-62 and 90-112
553482000459	1 transmembrane helix predicted for SEQ0086 by TMHMM2.0 at aa 73-95
553482000460	Domain of unknown function (DUF4176); Region: DUF4176; pfam13780
553482000461	H+ Antiporter protein; Region: 2A0121; TIGR00900
553482000462	10 transmembrane helices predicted for SEQ0089 by TMHMM2.0 at aa 13-35, 40-62, 75-94, 99-121, 161-183, 216-237, 250-272, 282-299, 306-323 and 343-365
553482000463	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482000464	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482000465	LPXTG-motif cell wall anchor domain; Region: LPXTG_anchor; TIGR01167
553482000466	2 transmembrane helices predicted for SEQ0090 by TMHMM2.0 at aa 13-32 and 375-392
553482000467	HMMPfam hit to PF01391, Collagen triple helix repeat (20 copi, score 2.9e-13
553482000468	HMMPfam hit to PF01391, Collagen triple helix repeat (20 copi, score 3.6e-14
553482000469	HMMPfam hit to PF01391, Collagen triple helix repeat (20 copi, score 3.6e-16
553482000470	HMMPfam hit to PF00746, Gram positive anchor, score 1.3e-07
553482000471	PS00343 Gram-positive cocci surface proteins 'anchoring' hexapeptide.
553482000472	isopentenyl-diphosphate delta-isomerase, type 1; Region: IPP_isom_1; TIGR02150
553482000473	Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly...; Region: Nudix_Hydrolase_34; cd04693
553482000474	nudix motif; other site
553482000475	HMMPfam hit to PF00293, NUDIX domain, score 4.3e-22
553482000476	PS00893 mutT domain signature.
553482000477	4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Provisional; Region: ipk; PRK00128
553482000478	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
553482000479	GHMP kinases C terminal; Region: GHMP_kinases_C; pfam08544
553482000480	HMMPfam hit to PF00288, GHMP kinases N terminal domain, score 1.3e-18
553482000481	HMMPfam hit to PF08544, GHMP kinases C terminal, score 3e-09
553482000482	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
553482000483	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
553482000484	putative Zn2+ binding site [ion binding]; other site
553482000485	putative DNA binding site [nucleotide binding]; other site
553482000486	HMMPfam hit to PF01047, MarR family, score 6.7e-14
553482000487	HMMPfam hit to PF08279, HTH domain, score 0.0028
553482000488	Predicted helix-turn-helix motif with score 2017.000, SD 6.06 at aa 52-73, sequence LTNTDLAKRLNISQAAVTKAIK
553482000489	ABC-type cobalt transport system, ATPase component [Inorganic ion transport and metabolism]; Region: CbiO; COG1122
553482000490	ATP-binding cassette domain of the metal-type transporters; Region: ABC_Metallic_Cations; cd03235
553482000491	HMMPfam hit to PF00005, ABC transporter, score 2.6e-47
553482000492	PS00211 ABC transporters family signature.
553482000493	ABC-type Mn2+/Zn2+ transport systems, permease components [Inorganic ion transport and metabolism]; Region: ZnuB; COG1108
553482000494	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
553482000495	ABC-ATPase subunit  interface; other site
553482000496	dimer interface [polypeptide binding]; other site
553482000497	putative PBP binding regions; other site
553482000498	HMMPfam hit to PF00950, ABC 3 transport family, score 1.7e-90
553482000499	7 transmembrane helices predicted for SEQ0095 by TMHMM2.0 at aa 10-32, 53-75, 85-107, 134-156, 176-198, 219-241 and 245-267
553482000500	HMMPfam hit to PF01032, FecCD transport family, score 0.004
553482000501	tyrosyl-tRNA synthetase; Validated; Region: PRK05912
553482000502	catalytic core domain of tyrosinyl-tRNA synthetase; Region: TyrRS_core; cd00805
553482000503	active site
553482000504	HIGH motif; other site
553482000505	dimer interface [polypeptide binding]; other site
553482000506	KMSKS motif; other site
553482000507	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
553482000508	RNA binding surface [nucleotide binding]; other site
553482000509	HMMPfam hit to PF01479, S4 domain, score 1.2e-06
553482000510	HMMPfam hit to PF00579, tRNA synthetases class I (W and Y), score 2.6e-116
553482000511	PS00178 Aminoacyl-transfer RNA synthetases class-I signature.
553482000512	Membrane carboxypeptidase (penicillin-binding protein) [Cell envelope biogenesis, outer membrane]; Region: MrcB; COG0744
553482000513	Transglycosylase; Region: Transgly; pfam00912
553482000514	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
553482000515	1 transmembrane helix predicted for SEQ0097 by TMHMM2.0 at aa 38-60
553482000516	HMMPfam hit to PF00912, Transglycosylase, score 1.6e-76
553482000517	PS00402 Binding-protein-dependent transport systems inner membrane comp. sign.
553482000518	HMMPfam hit to PF00905, Penicillin binding protein transpeptid, score 7.9e-15
553482000519	PS00017 ATP/GTP-binding site motif A (P-loop).
553482000520	DNA-directed RNA polymerase subunit beta; Reviewed; Region: rpoB; PRK00405
553482000521	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cl17585
553482000522	RNA polymerase Rpb2, domain 2; Region: RNA_pol_Rpb2_2; pfam04561
553482000523	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cl17585
553482000524	RNA polymerase beta subunit external 1 domain; Region: RNA_pol_Rpb2_45; pfam10385
553482000525	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cd00653
553482000526	RPB1 interaction site [polypeptide binding]; other site
553482000527	RPB10 interaction site [polypeptide binding]; other site
553482000528	RPB11 interaction site [polypeptide binding]; other site
553482000529	RPB3 interaction site [polypeptide binding]; other site
553482000530	RPB12 interaction site [polypeptide binding]; other site
553482000531	HMMPfam hit to PF04563, RNA polymerase beta subunit, score 3e-55
553482000532	HMMPfam hit to PF04561, RNA polymerase Rpb2, domain, score 1.9e-08
553482000533	HMMPfam hit to PF04565, RNA polymerase Rpb2, domain, score 1.6e-39
553482000534	HMMPfam hit to PF00562, RNA polymerase Rpb2, domain, score 1.4e-211
553482000535	PS01166 RNA polymerases beta chain signature.
553482000536	HMMPfam hit to PF04560, RNA polymerase Rpb2, domain, score 1.1e-49
553482000537	DNA-directed RNA polymerase subunit beta'; Provisional; Region: PRK00566
553482000538	RNA polymerase Rpb1, domain 1; Region: RNA_pol_Rpb1_1; pfam04997
553482000539	RNA polymerase I subunit A N-terminus; Region: RPOLA_N; smart00663
553482000540	RNA polymerase Rpb1, domain 3; Region: RNA_pol_Rpb1_3; pfam04983
553482000541	RNA polymerase Rpb1, domain 4; Region: RNA_pol_Rpb1_4; pfam05000
553482000542	Largest subunit (beta') of Bacterial DNA-dependent RNA polymerase (RNAP), C-terminal domain; Region: RNAP_beta'_C; cd02655
553482000543	Rpb1 (beta') - Rpb6 (omega) interaction site [polypeptide binding]; other site
553482000544	Rpb1 (beta') - Rpb2 (beta) interaction site [polypeptide binding]; other site
553482000545	G-loop; other site
553482000546	DNA binding site [nucleotide binding]
553482000547	HMMPfam hit to PF04997, RNA polymerase Rpb1, domain, score 2.2e-142
553482000548	HMMPfam hit to PF00623, RNA polymerase Rpb1, domain, score 1.3e-83
553482000549	HMMPfam hit to PF04983, RNA polymerase Rpb1, domain, score 6.3e-71
553482000550	HMMPfam hit to PF05000, RNA polymerase Rpb1, domain, score 4.2e-23
553482000551	HMMPfam hit to PF04998, RNA polymerase Rpb1, domain, score 1.7e-78
553482000552	gene remnant. Similar to C-terminal region Streptococcus pneumoniae IS1167 transposase UniProt:Q97SC5 (EMBL:AE005672 (422 aa) fasta scores: E()=5e-12, 65.714% id in 70 aa
553482000553	Acyltransferase family; Region: Acyl_transf_3; pfam01757
553482000554	10 transmembrane helices predicted for SEQ0103 by TMHMM2.0 at aa 13-35, 50-67, 87-104, 119-141, 154-176, 196-215, 228-247, 252-271, 284-306 and 316-338
553482000555	Protein of unknown function (DUF1033); Region: DUF1033; pfam06279
553482000556	HMMPfam hit to PF06279, Protein of unknown function (DUF1033), score 6.2e-68
553482000557	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4652
553482000558	Protein of unknown function (DUF1430); Region: DUF1430; pfam07242
553482000559	8 transmembrane helices predicted for SEQ0105 by TMHMM2.0 at aa 5-24, 153-175, 203-225, 229-260, 273-295, 563-585, 605-627 and 631-650
553482000560	HMMPfam hit to PF07242, Protein of unknown function (DUF1430), score 4.1e-37
553482000561	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
553482000562	putative bacteriocin export ABC transporter, lactococcin 972 group; Region: L_ocin_972_ABC; TIGR03608
553482000563	Walker A/P-loop; other site
553482000564	ATP binding site [chemical binding]; other site
553482000565	Q-loop/lid; other site
553482000566	ABC transporter signature motif; other site
553482000567	Walker B; other site
553482000568	D-loop; other site
553482000569	H-loop/switch region; other site
553482000570	HMMPfam hit to PF00005, ABC transporter, score 8.7e-53
553482000571	PS00017 ATP/GTP-binding site motif A (P-loop).
553482000572	PS00092 N-6 Adenine-specific DNA methylases signature.
553482000573	Type II/IV secretion system protein; Region: T2SE; pfam00437
553482000574	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
553482000575	Walker A motif; other site
553482000576	ATP binding site [chemical binding]; other site
553482000577	Walker B motif; other site
553482000578	HMMPfam hit to PF00437, Type II/IV secretion system protein, score 4e-30
553482000579	PS00017 ATP/GTP-binding site motif A (P-loop).
553482000580	PS00662 Bacterial type II secretion system protein E signature.
553482000581	Type II secretory pathway, component PulF [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PulF; COG1459
553482000582	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
553482000583	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
553482000584	HMMPfam hit to PF00482, Bacterial type II secretion system protein F, score 5.1e-16
553482000585	3 transmembrane helices predicted for SEQ0108 by TMHMM2.0 at aa 124-146, 161-183 and 315-337
553482000586	HMMPfam hit to PF00482, Bacterial type II secretion system protein F, score 9.4e-20
553482000587	Competence protein ComGC [Intracellular trafficking and secretion]; Region: ComGC; COG4537
553482000588	HMMPfam hit to PF07963, Prokaryotic N-terminal methylation motif, score 6.8e-06
553482000589	1 transmembrane helix predicted for SEQ0109 by TMHMM2.0 at aa 15-37
553482000590	1 transmembrane helix predicted for SEQ0110 by TMHMM2.0 at aa 7-29
553482000591	Type II secretory pathway pseudopilin; Region: PulG; pfam11773
553482000592	1 transmembrane helix predicted for SEQ0111 by TMHMM2.0 at aa 12-34
553482000593	Competence protein ComGF [Intracellular trafficking and secretion]; Region: ComGF; COG4940
553482000594	1 transmembrane helix predicted for SEQ0112 by TMHMM2.0 at aa 9-31
553482000595	PS00012 Phosphopantetheine attachment site.
553482000596	1 transmembrane helix predicted for SEQ0113 by TMHMM2.0 at aa 9-31
553482000597	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
553482000598	Helix-turn-helix domain; Region: HTH_28; pfam13518
553482000599	Predicted helix-turn-helix motif with score 1140.000, SD 3.07 at aa 19-40, sequence KSIKCLSEKFSIAESDLKYMIR
553482000600	HMMPfam hit to PF01527, Transposase, score 0.00062
553482000601	HMMPfam hit to PF02178, no description, score 0.21
553482000603	Adenine-specific DNA methylase [DNA replication, recombination, and repair]; Region: COG0827
553482000604	Methyltransferase domain; Region: Methyltransf_26; pfam13659
553482000605	acetate kinase A/propionate kinase 2; Reviewed; Region: PRK00180
553482000606	propionate/acetate kinase; Provisional; Region: PRK12379
553482000607	HMMPfam hit to PF00871, Acetokinase family, score 4.1e-196
553482000608	PS01076 Acetate and butyrate kinases family signature 2.
553482000609	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
553482000610	Transposase; Region: HTH_Tnp_1; cl17663
553482000611	HMMPfam hit to PF01527, Transposase, score 0.00051
553482000612	putative transposase OrfB; Reviewed; Region: PHA02517
553482000613	HTH-like domain; Region: HTH_21; pfam13276
553482000614	Integrase core domain; Region: rve; pfam00665
553482000615	Integrase core domain; Region: rve_2; pfam13333
553482000616	HMMPfam hit to PF00665, Integrase core domain, score 7.5e-38
553482000617	3 transmembrane helices predicted for SEQ0121 by TMHMM2.0 at aa 7-29, 104-126 and 147-169
553482000618	Transcriptional antiterminator [Transcription]; Region: BglG; COG3711
553482000619	PRD domain; Region: PRD; pfam00874
553482000620	PTS_IIB_bgl_like: the PTS (phosphotransferase system) IIB domain of a family of sensory systems composed of a membrane-bound sugar-sensor (similar to BglF) and a transcription antiterminator (similar to BglG) which regulate expression of genes involved...; Region: PTS_IIB_bgl_like; cd05568
553482000621	active site
553482000622	P-loop; other site
553482000623	phosphorylation site [posttranslational modification]
553482000624	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
553482000625	active site
553482000626	phosphorylation site [posttranslational modification]
553482000627	HMMPfam hit to PF00874, PRD domain, score 1.2e-14
553482000628	HMMPfam hit to PF00359, Phosphoenolpyruvate-dependent sugar phosph, score 9.8e-27
553482000629	PS00372 PTS EIIA domains phosphorylation site signature 2.
553482000630	PTS_IIB_ascorbate: subunit IIB of enzyme II (EII) of the L-ascorbate-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is an L-ascorbate-specific permease with two cytoplasmic subunits (IIA and IIB) and a...; Region: PTS_IIB_ascorbate; cd05563
553482000631	active site
553482000632	P-loop; other site
553482000633	phosphorylation site [posttranslational modification]
553482000634	HMMPfam hit to PF02302, PTS system, Lactose/Cellobiose specific IIB, score 1.4e-26
553482000635	PTS system ascorbate-specific transporter subunit IIC; Reviewed; Region: ulaA; PRK09410
553482000636	HMMPfam hit to PF04215, sugar-specific permease, SgaT/UlaA, score 2.6e-113
553482000637	11 transmembrane helices predicted for SEQ0124 by TMHMM2.0 at aa 4-26, 33-55, 86-108, 115-137, 141-163, 220-242, 257-279, 311-333, 337-359, 371-393 and 416-438
553482000638	PS00453 FKBP-type peptidyl-prolyl cis-trans isomerase signature 1.
553482000639	PS00017 ATP/GTP-binding site motif A (P-loop).
553482000640	Thiamine pyrophosphate (TPP) family, Transketolase (TK) subfamily, TPP-binding module; TK catalyzes the transfer of a two-carbon unit from ketose phosphates to aldose phosphates. In heterotrophic organisms, TK provides a link between glycolysis and the...; Region: TPP_TK; cd02012
553482000641	TPP-binding site [chemical binding]; other site
553482000642	dimer interface [polypeptide binding]; other site
553482000643	HMMPfam hit to PF00456, Transketolase, thiamine diphosphate b, score 1.2e-19
553482000644	Transketolase, C-terminal subunit [Carbohydrate transport and metabolism]; Region: COG3958
553482000645	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
553482000646	PYR/PP interface [polypeptide binding]; other site
553482000647	dimer interface [polypeptide binding]; other site
553482000648	TPP binding site [chemical binding]; other site
553482000649	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
553482000650	HMMPfam hit to PF02779, Transketolase, pyridine binding domai, score 1.4e-15
553482000651	HMMPfam hit to PF02780, Transketolase, C-terminal domain, score 2e-16
553482000652	Predicted metalloendopeptidase [Posttranslational modification, protein turnover, chaperones]; Region: PepO; COG3590
553482000653	Peptidase family M13 includes neprilysin, endothelin-converting enzyme I; Region: M13; cd08662
553482000654	active site
553482000655	Zn binding site [ion binding]; other site
553482000656	HMMPfam hit to PF05649, Peptidase family M13, score 1.2e-171
553482000657	HMMPfam hit to PF01431, Peptidase family M13, score 2.5e-73
553482000658	PS00142 Neutral zinc metallopeptidases, zinc-binding region signature.
553482000659	elongation factor Ts; Provisional; Region: tsf; PRK09377
553482000660	UBA/TS-N domain; Region: UBA; pfam00627
553482000661	Elongation factor TS; Region: EF_TS; pfam00889
553482000662	HMMPfam hit to PF00889, Elongation factor TS, score 2.7e-54
553482000663	HMMPfam hit to PF00627, UBA/TS-N domain, score 5.5e-12
553482000664	Ribosomal protein S2 (RPS2), involved in formation of the translation initiation complex, where it might contact the messenger RNA and several components of the ribosome. It has been shown that in Escherichia coli RPS2 is essential for the binding of...; Region: RPS2; cd01425
553482000665	rRNA interaction site [nucleotide binding]; other site
553482000666	S8 interaction site; other site
553482000667	putative laminin-1 binding site; other site
553482000668	HMMPfam hit to PF00318, Ribosomal protein S2, score 1.5e-100
553482000669	PS00962 Ribosomal protein S2 signature 1.
553482000670	alkyl hydroperoxide reductase subunit F; Provisional; Region: PRK15317
553482000671	Alkyl hydroperoxide reductase F subunit (AhpF) N-terminal domain (NTD) family, N-terminal TRX-fold subdomain; AhpF is a homodimeric flavoenzyme which catalyzes the NADH-dependent reduction of the peroxiredoxin AhpC, which in turn catalyzes the reduction...; Region: AhpF_NTD_N; cd02974
553482000672	catalytic residue [active]
553482000673	TRX-GRX-like family, Alkyl hydroperoxide reductase F subunit (AhpF) N-terminal domain (NTD) subfamily, C-terminal TRX-fold subdomain; AhpF is a homodimeric flavoenzyme which catalyzes the NADH-dependent reduction of the peroxiredoxin AhpC, which then...; Region: AhpF_NTD_C; cd03026
553482000674	catalytic residues [active]
553482000675	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
553482000676	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
553482000677	HMMPfam hit to PF07992, Pyridine nucleotide-disulphide oxidoreduc, score 5.9e-51
553482000678	HMMPfam hit to PF00070, Pyridine nucleotide-disulphide oxidoreduc, score 1.7e-17
553482000679	PS00573 Pyridine nucleotide-disulphide oxidoreductases class-II active site.
553482000680	HMMPfam hit to PF00070, Pyridine nucleotide-disulphide oxidoreduc, score 0.0026
553482000681	peroxiredoxin; Region: AhpC; TIGR03137
553482000682	Peroxiredoxin (PRX) family, Typical 2-Cys PRX subfamily; PRXs are thiol-specific antioxidant (TSA) proteins, which confer a protective role in cells through its peroxidase activity by reducing hydrogen peroxide, peroxynitrite, and organic hydroperoxides; Region: PRX_Typ2cys; cd03015
553482000683	dimer interface [polypeptide binding]; other site
553482000684	decamer (pentamer of dimers) interface [polypeptide binding]; other site
553482000685	catalytic triad [active]
553482000686	peroxidatic and resolving cysteines [active]
553482000687	HMMPfam hit to PF00578, AhpC/TSA family, score 7.7e-90
553482000688	HMMPfam hit to PF08534, Redoxin, score 6e-14
553482000689	prophage phiSeq1
553482000690	phiLC3 phage and phage-related integrases, site-specific recombinases, DNA breaking-rejoining enzymes, C-terminal catalytic domain. This CD includes various bacterial (mainly gram positive) and phage integrases, including those similar to Lactococcus...; Region: INT_phiLC3_C; cd01189
553482000691	Int/Topo IB signature motif; other site
553482000692	HMMPfam hit to PF00589, Phage integrase family, score 4.5e-19
553482000693	PemK-like protein; Region: PemK; pfam02452
553482000694	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
553482000695	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
553482000696	non-specific DNA binding site [nucleotide binding]; other site
553482000697	salt bridge; other site
553482000698	sequence-specific DNA binding site [nucleotide binding]; other site
553482000699	Predicted transcriptional regulator [Transcription]; Region: COG2932
553482000700	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
553482000701	Catalytic site [active]
553482000702	HMMPfam hit to PF00717, Peptidase S24-like, score 4.8e-17
553482000703	HMMPfam hit to PF01381, Helix-turn-helix, score 1.7e-15
553482000704	Predicted helix-turn-helix motif with score 2380.000, SD 7.29 at aa 16-37, sequence VSVEELAKKLGVSKTTIYRYEK
553482000705	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed...; Region: HTH_Hin_like; cl17393
553482000706	DNA-binding interface [nucleotide binding]; DNA binding site
553482000707	Predicted helix-turn-helix motif with score 1591.000, SD 4.61 at aa 16-37, sequence TTQQAVADSIGIDRSTFYRKMK
553482000708	KTSC domain; Region: KTSC; pfam13619
553482000709	Predicted helix-turn-helix motif with score 1182.000, SD 3.21 at aa 38-59, sequence LNKKQISKMLGVDPKTFDVRFN
553482000710	Helix-turn-helix domain; Region: HTH_36; pfam13730
553482000711	DnaD and phage-associated domain; Region: DnaD_dom; TIGR01446
553482000712	RecT family; Region: RecT; cl04285
553482000713	HMMPfam hit to PF03837, RecT family, score 2.4e-66
553482000714	PDDEXK-like domain of unknown function (DUF3799); Region: DUF3799; pfam12684
553482000715	CDS contains a frameshift after codon 18. Similar to Streptococcus pyogenes serotype M18 phage protein UniProt:Q8P088 (EMBL:AE010065 (137 aa) fasta scores: E()=5.3e-45, 96.350% id in 137 aa. Possible alternative translational start site after codon 24 which may generate a functional protein. Similar to Streptococcus pyogenes serotype M18 phage protein UniProt:Q8P1S1 (EMBL:AE010005 (113 aa) fasta scores: E()=3.6e-36, 98.230% id in 113 aa
553482000716	Protein of unknwon function (DUF3310); Region: DUF3310; pfam11753
553482000717	YopX protein; Region: YopX; cl09859
553482000718	1 transmembrane helix predicted for SEQ0157 by TMHMM2.0 at aa 26-45
553482000719	DNA modification methylase [DNA replication, recombination, and repair]; Region: COG0863
553482000720	DNA methylase; Region: N6_N4_Mtase; cl17433
553482000721	HMMPfam hit to PF01555, DNA methylase, score 1.2e-05
553482000722	PS00092 N-6 Adenine-specific DNA methylases signature.
553482000723	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482000724	Protein of unknown function (DUF1642); Region: DUF1642; pfam07852
553482000725	HMMPfam hit to PF07852, Protein of unknown function (DUF1642), score 2.4e-20
553482000726	phage transcriptional regulator, ArpU family; Region: phage_arpU; TIGR01637
553482000727	Stage 0 sporulation protein J (antagonist of Soj) containing ParB-like nuclease domain [Transcription]; Region: Spo0J; COG1475
553482000728	ParB-like nuclease domain; Region: ParBc; pfam02195
553482000729	DNA modification methylase [DNA replication, recombination, and repair]; Region: COG0863
553482000730	DNA methylase; Region: N6_N4_Mtase; pfam01555
553482000731	HMMPfam hit to PF02195, ParB-like nuclease domain, score 7.8e-11
553482000732	HMMPfam hit to PF01555, DNA methylase, score 7.9e-15
553482000733	PS00092 N-6 Adenine-specific DNA methylases signature.
553482000734	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482000735	Phage terminase large subunit; Region: Terminase_3; cl12054
553482000736	Terminase-like family; Region: Terminase_6; pfam03237
553482000737	HMMPfam hit to PF03237, Terminase-like family, score 1.6e-27
553482000738	PS00017 ATP/GTP-binding site motif A (P-loop).
553482000739	phage portal protein, putative, A118 family; Region: A118_put_portal; TIGR01542
553482000740	Phage portal protein, SPP1 Gp6-like; Region: Phage_prot_Gp6; pfam05133
553482000741	Phage minor capsid protein 2; Region: Phage_min_cap2; pfam06152
553482000742	HMMPfam hit to PF06152, Phage minor capsid protein, score 5.5e-213
553482000743	Head-Tail Connector Proteins gp6 and gp15, and similar proteins; Region: gp6_gp15_like; cl12049
553482000744	Minor capsid protein; Region: Minor_capsid_1; pfam10665
553482000745	Minor capsid protein; Region: Minor_capsid_2; pfam11114
553482000746	Minor capsid protein from bacteriophage; Region: Minor_capsid_3; pfam12691
553482000747	PS00018 EF-hand calcium-binding domain.
553482000748	Bacteriophage Gp15 protein; Region: Phage_Gp15; pfam06854
553482000749	HMMPfam hit to PF06854, Bacteriophage Gp15 protein, score 3.8e-126
553482000750	tape measure domain; Region: tape_meas_nterm; TIGR02675
553482000751	Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; Region: SPEC; cl02488
553482000752	linker region; other site
553482000753	4 transmembrane helices predicted for SEQ0180 by TMHMM2.0 at aa 305-327, 334-356, 397-419 and 432-454
553482000754	Phage-related protein [Function unknown]; Region: COG4722
553482000755	Phage tail protein; Region: Sipho_tail; cl17486
553482000756	Phage-related protein [Function unknown]; Region: PblB; COG4926
553482000757	Prophage endopeptidase tail; Region: Prophage_tail; cl12123
553482000758	Collagen triple helix repeat (20 copies); Region: Collagen; pfam01391
553482000759	HMMPfam hit to PF01391, Collagen triple helix repeat (20 copies), score 2.4e-06
553482000760	gp58-like protein; Region: Gp58; pfam07902
553482000761	HMMPfam hit to PF07902, gp58-like protein, score 0
553482000762	PS00043 Bacterial regulatory proteins, gntR family signature.
553482000763	Protein of unknown function (DUF1617); Region: DUF1617; pfam07761
553482000764	HMMPfam hit to PF07761, Protein of unknown function (DUF1617), score 2.9e-93
553482000765	Holin family; Region: Phage_holin_4; pfam05105
553482000766	HMMPfam hit to PF05105, Holin family, score 4e-23
553482000767	3 transmembrane helices predicted for SEQ0188 by TMHMM2.0 at aa 16-38, 53-75 and 80-99
553482000768	1 transmembrane helix predicted for SEQ0189 by TMHMM2.0 at aa 7-29
553482000769	Muramidase (flagellum-specific) [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FlgJ; COG1705
553482000770	CHAP domain; Region: CHAP; pfam05257
553482000771	Bacterial SH3 domain; Region: SH3_5; pfam08460
553482000772	HMMPfam hit to PF01832, Mannosyl-glycoprotein endo-beta-N-ace, score 2.7e-19
553482000773	PS00639 Eukaryotic thiol (cysteine) proteases histidine active site.
553482000774	HMMPfam hit to PF05257, CHAP domain, score 5.1e-25
553482000775	HMMPfam hit to PF08460, Bacterial SH3 domain, score 3.5e-09
553482000776	Predicted helix-turn-helix motif with score 1031.000, SD 2.70 at aa 16-37, sequence ITTYKIGKKIGESTQFLDRYKN
553482000777	Minor tail protein T; Region: Phage_tail_T; cl05636
553482000778	1 transmembrane helix predicted for SEQ0194 by TMHMM2.0 at aa 5-22
553482000779	Predicted helix-turn-helix motif with score 1139.000, SD 3.07 at aa 186-207, sequence TRIRDIALKFNIPETTLRGRYQ
553482000780	Predicted helix-turn-helix motif with score 1368.000, SD 3.85 at aa 83-104, sequence NKVSDLADKYGINQATLRNGIA
553482000781	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
553482000782	DNA-binding site [nucleotide binding]; DNA binding site
553482000783	RNA-binding motif; other site
553482000784	HMMPfam hit to PF00313, 'Cold-shock' DNA-binding domain, score 1.5e-43
553482000785	PS00352 'Cold-shock' DNA-binding domain signature.
553482000786	Transcriptional repressor of class III stress genes [Transcription]; Region: CtsR; COG4463
553482000787	PS00430 TonB-dependent receptor proteins signature 1.
553482000788	HMMPfam hit to PF05848, Firmicute transcriptional repressor of class, score 1e-99
553482000789	Predicted helix-turn-helix motif with score 1287.000, SD 3.57 at aa 26-47, sequence IKRSMLADSFQVVPSQINYVIK
553482000790	ATP-binding subunits of Clp protease and DnaK/DnaJ chaperones [Posttranslational modification, protein turnover, chaperones]; Region: clpA; COG0542
553482000791	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
553482000792	Walker A motif; other site
553482000793	ATP binding site [chemical binding]; other site
553482000794	Walker B motif; other site
553482000795	arginine finger; other site
553482000796	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
553482000797	Walker A motif; other site
553482000798	ATP binding site [chemical binding]; other site
553482000799	Walker B motif; other site
553482000800	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431
553482000801	HMMPfam hit to PF02861, Clp amino terminal domain, score 0.036
553482000802	PS00017 ATP/GTP-binding site motif A (P-loop).
553482000803	HMMPfam hit to PF02861, Clp amino terminal domain, score 0.27
553482000804	HMMPfam hit to PF00004, ATPase family associated with various cellul, score 5.3e-07
553482000805	PS00017 ATP/GTP-binding site motif A (P-loop).
553482000806	PS00870 Chaperonins clpA/B signature 1.
553482000807	HMMPfam hit to PF07724, ATPase family associated with various cellul, score 1.4e-100
553482000808	HMMPfam hit to PF07728, ATPase family associated with various cellul, score 6.3e-05
553482000809	PS00017 ATP/GTP-binding site motif A (P-loop).
553482000810	PS00871 Chaperonins clpA/B signature 2.
553482000811	1 transmembrane helix predicted for SEQ0202 by TMHMM2.0 at aa 7-24
553482000812	1 transmembrane helix predicted for SEQ0203 by TMHMM2.0 at aa 7-24
553482000813	Lipase.  Lipases are esterases that can hydrolyze long-chain acyl-triglycerides into di- and monoglycerides, glycerol, and free fatty acids at a water/lipid interface. A typical feature of lipases is "interfacial activation", the process of...; Region: Lipase; cl14883
553482000814	nucleophilic elbow; other site
553482000815	catalytic triad; other site
553482000816	putative transposase OrfB; Reviewed; Region: PHA02517
553482000817	HTH-like domain; Region: HTH_21; pfam13276
553482000818	Integrase core domain; Region: rve; pfam00665
553482000819	Integrase core domain; Region: rve_2; pfam13333
553482000820	HMMPfam hit to PF00665, Integrase core domain, score 1.1e-37
553482000821	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
553482000822	Helix-turn-helix domain; Region: HTH_28; pfam13518
553482000823	HMMPfam hit to PF01527, Transposase, score 0.00062
553482000824	HMMPfam hit to PF02178, no description, score 0.21
553482000825	Predicted helix-turn-helix motif with score 1140.000, SD 3.07 at aa 19-40, sequence KSIKCLSEKFSIAESDLKYMIR
553482000826	chaperonin GroEL; Reviewed; Region: groEL; PRK12849
553482000827	GroEL_like type I chaperonin. Chaperonins are involved in productive folding of proteins. They share a common general morphology, a double toroid of 2 stacked rings, each composed of 7-9 subunits. The symmetry of type I is seven-fold and they are found...; Region: GroEL; cd03344
553482000828	ring oligomerisation interface [polypeptide binding]; other site
553482000829	ATP/Mg binding site [chemical binding]; other site
553482000830	stacking interactions; other site
553482000831	hinge regions; other site
553482000832	HMMPfam hit to PF00118, TCP-1/cpn60 chaperonin family, score 4.5e-195
553482000833	PS00296 Chaperonins cpn60 signature.
553482000834	Chaperonin 10 Kd subunit (cpn10 or GroES); Cpn10 cooperates with chaperonin 60 (cpn60 or GroEL), an ATPase, to assist the folding and assembly of proteins and is found in eubacterial cytosol, as well as in the matrix of mitochondria and chloroplasts. It...; Region: cpn10; cd00320
553482000835	oligomerisation interface [polypeptide binding]; other site
553482000836	mobile loop; other site
553482000837	roof hairpin; other site
553482000838	HMMPfam hit to PF00166, Chaperonin 10 Kd subunit, score 2e-32
553482000839	PS00681 Chaperonins cpn10 signature.
553482000840	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
553482000841	Transposase; Region: HTH_Tnp_1; cl17663
553482000842	HMMPfam hit to PF01527, Transposase, score 0.00051
553482000843	putative transposase OrfB; Reviewed; Region: PHA02517
553482000844	HTH-like domain; Region: HTH_21; pfam13276
553482000845	Integrase core domain; Region: rve; pfam00665
553482000846	Integrase core domain; Region: rve_2; pfam13333
553482000847	HMMPfam hit to PF00665, Integrase core domain, score 2.2e-37
553482000848	MutT homolog-1 (MTH1) is a member of the Nudix hydrolase superfamily. MTH1, the mammalian counterpart of MutT, hydrolyzes oxidized purine nucleoside triphosphates, such as 8-oxo-dGTP and 2-hydroxy-ATP, to monophosphates, thereby preventing the...; Region: MTH1; cd03427
553482000849	putative active site [active]
553482000850	nucleotide binding site [chemical binding]; other site
553482000851	nudix motif; other site
553482000852	putative metal binding site [ion binding]; other site
553482000853	HMMPfam hit to PF00293, NUDIX domain, score 1.1e-14
553482000854	PS00893 mutT domain signature.
553482000855	CDS contains a frameshift after codon 207. Similar to Streptococcus ratti MutR-like protein UniProt:Q3YB74 (EMBL:DQ145753 (292 aa) fasta scores: E()=7e-56, 56.842% id in 285 aa
553482000856	2 transmembrane helices predicted for SEQ0216 by TMHMM2.0 at aa 21-43 and 74-96
553482000857	9 transmembrane helices predicted for SEQ0217 by TMHMM2.0 at aa 13-35, 93-112, 119-141, 161-183, 204-226, 241-263, 297-319, 323-345 and 357-376
553482000858	PS00133 Zinc carboxypeptidases, zinc-binding region 2 signature.
553482000859	3 transmembrane helices predicted for SEQ0218 by TMHMM2.0 at aa 7-29, 56-78 and 138-155
553482000860	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
553482000861	putative bacteriocin export ABC transporter, lactococcin 972 group; Region: L_ocin_972_ABC; TIGR03608
553482000862	Walker A/P-loop; other site
553482000863	ATP binding site [chemical binding]; other site
553482000864	Q-loop/lid; other site
553482000865	ABC transporter signature motif; other site
553482000866	Walker B; other site
553482000867	D-loop; other site
553482000868	H-loop/switch region; other site
553482000869	HMMPfam hit to PF00005, ABC transporter, score 3.3e-08
553482000870	PS00017 ATP/GTP-binding site motif A (P-loop).
553482000871	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482000872	4 transmembrane helices predicted for SEQ0220 by TMHMM2.0 at aa 13-32, 47-69, 76-95 and 115-134
553482000873	4 transmembrane helices predicted for SEQ0221 by TMHMM2.0 at aa 5-27, 68-85, 92-114 and 129-151
553482000874	Predicted membrane protein [Function unknown]; Region: COG4640
553482000875	1 transmembrane helix predicted for SEQ0222 by TMHMM2.0 at aa 13-32
553482000876	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
553482000877	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
553482000878	active site
553482000879	HMMPfam hit to PF00849, RNA pseudouridylate synthase, score 1.6e-47
553482000880	PS01129 Rlu family of pseudouridine synthase signature.
553482000881	Transglutaminase-like superfamily; Region: Transglut_core; pfam01841
553482000882	YjgF, YER057c, and UK114 belong to a large family of proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no...; Region: YjgF_YER057c_UK114_family; cd00448
553482000883	homotrimer interaction site [polypeptide binding]; other site
553482000884	putative active site [active]
553482000885	HMMPfam hit to PF01042, Endoribonuclease L-PSP, score 0.0017
553482000886	Membrane carboxypeptidase (penicillin-binding protein) [Cell envelope biogenesis, outer membrane]; Region: MrcB; COG0744
553482000887	Transglycosylase; Region: Transgly; pfam00912
553482000888	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
553482000889	1 transmembrane helix predicted for SEQ0227 by TMHMM2.0 at aa 100-122
553482000890	HMMPfam hit to PF00912, Transglycosylase, score 3e-80
553482000891	PS00017 ATP/GTP-binding site motif A (P-loop).
553482000892	HMMPfam hit to PF00905, Penicillin binding protein transpeptid, score 1.5e-44
553482000893	PS00017 ATP/GTP-binding site motif A (P-loop).
553482000894	50S ribosomal protein L33; Validated; Region: rpmG; PRK00504
553482000895	HMMPfam hit to PF00471, Ribosomal protein L33, score 5.1e-12
553482000896	Preprotein translocase subunit SecE [Intracellular trafficking and secretion]; Region: SecE; COG0690
553482000897	1 transmembrane helix predicted for SEQ0229 by TMHMM2.0 at aa 26-48
553482000898	transcription antitermination protein NusG; Validated; Region: nusG; PRK05609
553482000899	Bacterial N-Utilization Substance G (NusG) N-terminal (NGN) domain, subgroup 1; Region: NGN_Bact_1; cd09891
553482000900	putative homodimer interface [polypeptide binding]; other site
553482000901	NusG contains an NGN domain at its N-terminus and KOW motif at its C-terminus; Region: KOW_NusG; cd06091
553482000902	heterodimer interface [polypeptide binding]; other site
553482000903	homodimer interface [polypeptide binding]; other site
553482000904	HMMPfam hit to PF02357, Transcription termination factor nusG, score 8e-52
553482000905	HMMPfam hit to PF00467, KOW motif, score 1.4e-07
553482000906	M protein trans-acting positive regulator (MGA) HTH domain; Region: HTH_Mga; pfam08280
553482000907	Mga helix-turn-helix domain; Region: Mga; pfam05043
553482000908	M protein trans-acting positive regulator (MGA) PRD domain; Region: PRD_Mga; pfam08270
553482000909	HMMPfam hit to PF08280, M protein trans-acting positive regulator (M, score 3.7e-13
553482000910	HMMPfam hit to PF05043, Mga helix-turn-helix domain, score 3.3e-29
553482000911	Predicted helix-turn-helix motif with score 1528.000, SD 4.39 at aa 103-124, sequence ASLDDLAEALFISLSTLKRLIR
553482000912	HMMPfam hit to PF08270, M protein trans-acting positive regulator (M, score 4.9e-33
553482000913	gene remnant. CDS lacks an N-terminal signal sequence which is required for processing of this cell surface-anchored protein. Similar to the C-terminus of Streptococcus pyogenes serotype M18 Streptococcal protective antigen Spa UniProt:Q8NZA4 (EMBL:AE010108 (570 aa) fasta scores: E()=9.3e-13, 44.062% id in 320 aa
553482000914	HMMPfam hit to PF00746, Gram positive anchor, score 1.1e-08
553482000915	PS00343 Gram-positive cocci surface proteins 'anchoring' hexapeptide.
553482000916	1 transmembrane helix predicted for SEQ0232 by TMHMM2.0 at aa 251-273
553482000917	leucyl-tRNA synthetase; Validated; Region: leuS; PRK00390
553482000918	catalytic core domain of leucyl-tRNA synthetases; Region: LeuRS_core; cd00812
553482000919	HIGH motif; other site
553482000920	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
553482000921	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
553482000922	active site
553482000923	KMSKS motif; other site
553482000924	Anticodon-binding domain of bacterial and eukaryotic mitochondrial leucyl tRNA synthetases; Region: Anticodon_Ia_Leu_BEm; cd07958
553482000925	tRNA binding surface [nucleotide binding]; other site
553482000926	HMMPfam hit to PF00133, tRNA synthetases class I (I, L, M and V), score 1.1e-12
553482000927	PS00178 Aminoacyl-transfer RNA synthetases class-I signature.
553482000928	HMMPfam hit to PF08264, Anticodon-binding domain, score 4.7e-07
553482000929	1 transmembrane helix predicted for SEQ0235 by TMHMM2.0 at aa 4-26
553482000930	CDS lacks appropriate translational start site and therefore does not have an intact N-terminal signal sequence. Similar to Streptococcus pneumoniae hypothetical protein SPR1549 UniProt:Q8CYF3 (EMBL:AE008523 (130 aa) fasta scores: E()=2.6e-11, 38.400% id in 125 aa
553482000931	6 transmembrane helices predicted for SEQ0237 by TMHMM2.0 at aa 7-26, 66-88, 109-131, 165-187, 194-216 and 236-253
553482000932	5 transmembrane helices predicted for SEQ0238 by TMHMM2.0 at aa 3-25, 60-82, 109-131, 141-163 and 176-198
553482000933	CDS contains a nonsense mutation (ochre) after codon 128. Similar to Streptococcus pneumoniae ABC transporter, ATP-binding protein UniProt:Q97PD4 (EMBL:AE005672 (210 aa) fasta scores: E()=1.8e-26, 52.913% id in 206 aa
553482000934	PS00017 ATP/GTP-binding site motif A (P-loop).
553482000935	PTS system ascorbate-specific transporter subunit IIC; Reviewed; Region: PRK12997
553482000936	HMMPfam hit to PF04215, sugar-specific permease, SgaT/UlaA, score 2.7e-250
553482000937	11 transmembrane helices predicted for SEQ0241 by TMHMM2.0 at aa 15-34, 41-63, 101-123, 132-154, 160-177, 237-257, 277-296, 339-361, 365-384, 397-419 and 434-456
553482000938	PTS_IIB_ascorbate: subunit IIB of enzyme II (EII) of the L-ascorbate-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is an L-ascorbate-specific permease with two cytoplasmic subunits (IIA and IIB) and a...; Region: PTS_IIB_ascorbate; cd05563
553482000939	active site
553482000940	P-loop; other site
553482000941	phosphorylation site [posttranslational modification]
553482000942	HMMPfam hit to PF02302, PTS system, Lactose/Cellobiose specific IIB, score 1e-25
553482000943	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
553482000944	active site
553482000945	phosphorylation site [posttranslational modification]
553482000946	HMMPfam hit to PF00359, Phosphoenolpyruvate-dependent sugar phosph, score 8.4e-34
553482000947	3-Keto-L-gulonate 6-phosphate decarboxylase (KGPDC) and D-arabino-3-hexulose-6-phosphate synthase (HPS). KGPDC catalyzes the formation of L-xylulose 5-phosphate and carbon dioxide from 3-keto-L-gulonate 6-phosphate as part of the anaerobic pathway for...; Region: KGPDC_HPS; cd04726
553482000948	active site
553482000949	dimer interface [polypeptide binding]; other site
553482000950	magnesium binding site [ion binding]; other site
553482000951	HMMPfam hit to PF00215, Orotidine 5'-phosphate decarboxylase / HUMP, score 1.8e-55
553482000952	putative L-xylulose 5-phosphate 3-epimerase; Reviewed; Region: PRK13210
553482000953	AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cd00019
553482000954	AP (apurinic/apyrimidinic) site pocket; other site
553482000955	DNA interaction; other site
553482000956	Metal-binding active site; metal-binding site
553482000957	HMMPfam hit to PF01261, Xylose isomerase-like TIM barrel, score 4e-45
553482000958	L-ribulose-5-phosphate 4-epimerase; Provisional; Region: araD; PRK13145
553482000959	L-ribulose-5-phosphate 4-epimerase; Reviewed; Region: araD; PRK08193
553482000960	intersubunit interface [polypeptide binding]; other site
553482000961	active site
553482000962	Zn2+ binding site [ion binding]; other site
553482000963	HMMPfam hit to PF00596, Class II Aldolase and Adducin N-terminal, score 7.1e-96
553482000964	PS00017 ATP/GTP-binding site motif A (P-loop).
553482000965	Transcriptional antiterminator [Transcription]; Region: BglG; COG3711
553482000966	PRD domain; Region: PRD; pfam00874
553482000967	PRD domain; Region: PRD; pfam00874
553482000968	PTS_IIB_bgl_like: the PTS (phosphotransferase system) IIB domain of a family of sensory systems composed of a membrane-bound sugar-sensor (similar to BglF) and a transcription antiterminator (similar to BglG) which regulate expression of genes involved...; Region: PTS_IIB_bgl_like; cd05568
553482000969	active site
553482000970	P-loop; other site
553482000971	phosphorylation site [posttranslational modification]
553482000972	HMMPfam hit to PF08279, HTH domain, score 0.001
553482000973	HMMPfam hit to PF00874, PRD domain, score 9.6e-15
553482000974	HMMPfam hit to PF00874, PRD domain, score 5.2e-16
553482000975	putative L-ascorbate 6-phosphate lactonase; Provisional; Region: PRK11709
553482000976	Predicted Zn-dependent hydrolases of the beta-lactamase fold [General function prediction only]; Region: COG2220
553482000977	ABC-type proline/glycine betaine transport system, ATPase component [Amino acid transport and metabolism]; Region: ProV; COG4175
553482000978	ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; Region: ABC_Pro_Gly_Betaine; cd03294
553482000979	Walker A/P-loop; other site
553482000980	ATP binding site [chemical binding]; other site
553482000981	Q-loop/lid; other site
553482000982	ABC transporter signature motif; other site
553482000983	Walker B; other site
553482000984	D-loop; other site
553482000985	H-loop/switch region; other site
553482000986	The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called...; Region: CBS_pair; cl15354
553482000987	HMMPfam hit to PF00005, ABC transporter, score 4e-64
553482000988	PS00017 ATP/GTP-binding site motif A (P-loop).
553482000989	PS00211 ABC transporters family signature.
553482000990	HMMPfam hit to PF00571, CBS domain pair, score 8.6e-13
553482000991	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
553482000992	dimer interface [polypeptide binding]; other site
553482000993	conserved gate region; other site
553482000994	putative PBP binding loops; other site
553482000995	ABC-ATPase subunit interface; other site
553482000996	ABC-type proline/glycine betaine transport systems, periplasmic components [Amino acid transport and metabolism]; Region: ProX; COG2113
553482000997	Substrate binding domain of ABC-type glycine betaine transport system; Region: OpuAC; pfam04069
553482000998	7 transmembrane helices predicted for SEQ0251 by TMHMM2.0 at aa 48-67, 72-91, 98-120, 144-166, 215-237, 252-269 and 292-314
553482000999	HMMPfam hit to PF00528, Binding-protein-dependent transport syst, score 1.4e-31
553482001000	PS00402 Binding-protein-dependent transport systems inner membrane comp. sign.
553482001001	HMMPfam hit to PF04069, Substrate binding domain of ABC-type gly, score 3e-93
553482001002	DNA polymerase I; Provisional; Region: PRK05755
553482001003	PIN domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: PIN_53EXO; cd09859
553482001004	active site
553482001005	metal binding site 1 [ion binding]; metal-binding site
553482001006	putative 5' ssDNA interaction site; other site
553482001007	metal binding site 3; metal-binding site
553482001008	metal binding site 2 [ion binding]; metal-binding site
553482001009	H3TH domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: H3TH_53EXO; cd09898
553482001010	putative DNA binding site [nucleotide binding]; other site
553482001011	putative metal binding site [ion binding]; other site
553482001012	inactive DEDDy 3'-5' exonuclease domain of Bacillus stearothermophilus DNA polymerase I and similar family-A DNA polymerases; Region: DNA_polA_I_Bacillus_like_exo; cd06140
553482001013	Polymerase I functions primarily to fill DNA gaps that arise during DNA repair, recombination and replication; Region: DNA_pol_A_pol_I_C; cd08637
553482001014	active site
553482001015	DNA binding site [nucleotide binding]
553482001016	catalytic site [active]
553482001017	HMMPfam hit to PF02739, 5'-3' exonuclease, N-terminal resolvase-, score 1.7e-93
553482001018	HMMPfam hit to PF01367, 5'-3' exonuclease, C-terminal SAM fold, score 5.8e-56
553482001019	HMMPfam hit to PF01612, 3'-5' exonuclease, score 0.011
553482001020	HMMPfam hit to PF00476, DNA polymerase family A, score 6.7e-212
553482001021	PS00447 DNA polymerase family A signature.
553482001022	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482001023	Predicted CoA-binding protein [General function prediction only]; Region: COG1832
553482001024	HMMPfam hit to PF02629, CoA binding domain, score 1.1e-06
553482001025	Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators; Region: Fur_like; cd07153
553482001026	metal binding site 2 [ion binding]; metal-binding site
553482001027	putative DNA binding helix; other site
553482001028	metal binding site 1 [ion binding]; metal-binding site
553482001029	dimer interface [polypeptide binding]; other site
553482001030	structural Zn2+ binding site [ion binding]; other site
553482001031	HMMPfam hit to PF01475, Ferric uptake regulator family, score 6.8e-50
553482001032	HMMPfam hit to PF00746, Gram positive anchor, score 1.8e-07
553482001033	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482001034	YSIRK type signal peptide; Region: YSIRK_signal; cl04650
553482001035	NPCBM/NEW2 domain; Region: NPCBM; cl07060
553482001036	F5/8 type C domain; Region: F5_F8_type_C; pfam00754
553482001037	HMMPfam hit to PF04650, YSIRK type signal peptide, score 2.5e-05
553482001038	1 transmembrane helix predicted for SEQ0257 by TMHMM2.0 at aa 21-40
553482001039	HMMPfam hit to PF08305, NPCBM domain, score 1.2e-16
553482001040	HMMPfam hit to PF02012, BNR/Asp-box repeat, score 0.63
553482001041	HMMPfam hit to PF02012, BNR/Asp-box repeat, score 2.3
553482001042	HMMPfam hit to PF00754, F5/8 type C domain, score 1.7e-12
553482001043	PS00017 ATP/GTP-binding site motif A (P-loop).
553482001044	Protein of unknown function (DUF975); Region: DUF975; pfam06161
553482001045	HMMPfam hit to PF06161, Protein of unknown function (DUF975), score 4e-79
553482001046	5 transmembrane helices predicted for SEQ0258 by TMHMM2.0 at aa 28-50, 60-82, 121-143, 153-175 and 220-242
553482001047	queuine tRNA-ribosyltransferase; Provisional; Region: tgt; PRK00112
553482001048	Queuine/archaeosine tRNA-ribosyltransferase [Translation, ribosomal structure and biogenesis]; Region: Tgt; COG0343
553482001049	HMMPfam hit to PF01702, Queuine tRNA-ribosyltransferase, score 4.8e-145
553482001050	Gram positive anchor; Region: Gram_pos_anchor; pfam00746
553482001051	1 transmembrane helix predicted for SEQ0260 by TMHMM2.0 at aa 13-35
553482001052	HMMPfam hit to PF01391, Collagen triple helix repeat (20 copi, score 3.5e-12
553482001053	HMMPfam hit to PF01391, Collagen triple helix repeat (20 copi, score 2.4e-12
553482001054	HMMPfam hit to PF01391, Collagen triple helix repeat (20 copi, score 1.4e-12
553482001055	HMMPfam hit to PF00746, Gram positive anchor, score 1.5e-11
553482001056	PS00343 Gram-positive cocci surface proteins 'anchoring' hexapeptide.
553482001057	putative transposase OrfB; Reviewed; Region: PHA02517
553482001058	HTH-like domain; Region: HTH_21; pfam13276
553482001059	Integrase core domain; Region: rve; pfam00665
553482001060	Integrase core domain; Region: rve_2; pfam13333
553482001061	HMMPfam hit to PF00665, Integrase core domain, score 1.1e-37
553482001062	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
553482001063	Helix-turn-helix domain; Region: HTH_28; pfam13518
553482001064	HMMPfam hit to PF01527, Transposase, score 0.00062
553482001065	HMMPfam hit to PF02178, no description, score 0.21
553482001066	Predicted helix-turn-helix motif with score 1140.000, SD 3.07 at aa 19-40, sequence KSIKCLSEKFSIAESDLKYMIR
553482001067	Zinc finger domain containing protein (CHY type) [Function unknown]; Region: COG4357
553482001068	CHY zinc finger; Region: zf-CHY; pfam05495
553482001069	HMMPfam hit to PF05495, CHY zinc finger, score 4e-25
553482001070	PS00190 Cytochrome c family heme-binding site signature.
553482001071	Uncharacterized conserved protein [General function prediction only]; Region: BioY; COG1268
553482001072	5 transmembrane helices predicted for SEQ0264 by TMHMM2.0 at aa 15-37, 49-71, 86-108, 115-137 and 147-169
553482001073	HMMPfam hit to PF02632, BioY family, score 3e-18
553482001074	Metal-dependent hydrolases of the beta-lactamase superfamily III [General function prediction only]; Region: ElaC; COG1234
553482001075	Nucleoside deaminases include adenosine, guanine and cytosine deaminases. These enzymes are Zn dependent and catalyze the deamination of nucleosides. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a...; Region: nucleoside_deaminase; cd01285
553482001076	nucleoside/Zn binding site; other site
553482001077	dimer interface [polypeptide binding]; other site
553482001078	catalytic motif [active]
553482001079	HMMPfam hit to PF00383, Cytidine and deoxycytidylate deaminas, score 6.7e-34
553482001080	PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature.
553482001081	PS00041 Bacterial regulatory proteins, araC family signature.
553482001082	Uncharacterized protein involved in cytokinesis, contains TGc (transglutaminase/protease-like) domain [Cell division and chromosome partitioning]; Region: CYK3; COG5279
553482001083	Transglutaminase-like superfamily; Region: Transglut_core; pfam01841
553482001084	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482001085	1 transmembrane helix predicted for SEQ0268 by TMHMM2.0 at aa 13-35
553482001086	Glycosyltransferases, probably involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: COG1215
553482001087	CESA_like is  the cellulose synthase superfamily; Region: CESA_like; cd06423
553482001088	Glycosyl transferase family group 2; Region: Glyco_trans_2_3; pfam13632
553482001089	DXD motif; other site
553482001090	5 transmembrane helices predicted for SEQ0269 by TMHMM2.0 at aa 7-29, 33-55, 319-341, 351-370 and 377-394
553482001091	HMMPfam hit to PF03142, Chitin synthase, score 0.0039
553482001092	HMMPfam hit to PF00535, Glycosyl transferase family, score 2.1e-31
553482001093	UDP-glucose 6-dehydrogenase; Provisional; Region: PRK15057
553482001094	NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; Region: NAD_Gly3P_dh_N; pfam01210
553482001095	UDP-glucose/GDP-mannose dehydrogenase family, central domain; Region: UDPG_MGDP_dh; pfam00984
553482001096	UDP binding domain; Region: UDPG_MGDP_dh_C; smart00984
553482001097	HMMPfam hit to PF03721, UDP-glucose/GDP-mannose dehydrogenase, score 5.5e-58
553482001098	HMMPfam hit to PF01210, NAD-dependent glycerol-3-phosphate deh, score 0.0011
553482001099	HMMPfam hit to PF00984, UDP-glucose/GDP-mannose dehydrogenase, score 1.6e-36
553482001100	HMMPfam hit to PF03720, UDP-glucose/GDP-mannose dehydrogenase, score 6.6e-06
553482001101	Prokaryotic UGPase catalyses the synthesis of UDP-glucose; Region: UGPase_prokaryotic; cd02541
553482001102	dTDP-glucose pyrophosphorylase [Cell envelope biogenesis, outer membrane]; Region: RfbA; COG1209
553482001103	active site
553482001104	tetramer interface; other site
553482001105	HMMPfam hit to PF00483, Nucleotidyl transferase, score 3.2e-20
553482001106	gene remnant. Similar to the N-terminal region of Streptococcus pyogenes serotype M1 integral membrane protein (rhomboid family) UniProt:Q491A8 (EMBL:CP000017 (223 aa) fasta scores: E()=6.5e-33, 70.229% id in 131 aa
553482001107	HMMPfam hit to PF01694, Rhomboid family, score 2.6e-05
553482001108	3 transmembrane helices predicted for SEQ0273 by TMHMM2.0 at aa 12-34, 61-83 and 96-115
553482001109	5-formyltetrahydrofolate cyclo-ligase family; Region: 5-FTHF_cyc-lig; pfam01812
553482001110	5-formyltetrahydrofolate cyclo-ligase [Coenzyme metabolism]; Region: COG0212; cl00360
553482001111	HMMPfam hit to PF01812, 5-formyltetrahydrofolate cyclo-ligase, score 1.4e-43
553482001112	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482001114	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
553482001115	Helix-turn-helix domain; Region: HTH_28; pfam13518
553482001116	HMMPfam hit to PF01527, Transposase, score 0.00062
553482001117	HMMPfam hit to PF02178, no description, score 0.21
553482001118	Predicted helix-turn-helix motif with score 1140.000, SD 3.07 at aa 19-40, sequence KSIKCLSEKFSIAESDLKYMIR
553482001119	Gram positive anchor; Region: Gram_pos_anchor; pfam00746
553482001120	1 transmembrane helix predicted for SEQ0280 by TMHMM2.0 at aa 48-70
553482001121	HMMPfam hit to PF01391, Collagen triple helix repeat (20 copi, score 1e-10
553482001122	HMMPfam hit to PF01391, Collagen triple helix repeat (20 copi, score 1.1e-10
553482001123	HMMPfam hit to PF00746, Gram positive anchor, score 1.5e-08
553482001124	PS00343 Gram-positive cocci surface proteins 'anchoring' hexapeptide.
553482001125	2 transmembrane helices predicted for SEQ0281 by TMHMM2.0 at aa 13-35 and 117-139
553482001126	PTS system glucitol/sorbitol-specific IIA component; Region: PTSIIA_gutA; pfam03829
553482001127	HMMPfam hit to PF03829, PTS system glucitol/sorbitol-specific IIA, score 3.2e-56
553482001128	Sorbitol phosphotransferase enzyme II N-terminus; Region: EIIBC-GUT_N; pfam03612
553482001129	PTS system, glucitol/sorbitol-specific, IIBC component; Region: EIIBC-GUT; TIGR00825
553482001130	Sorbitol phosphotransferase enzyme II C-terminus; Region: EIIBC-GUT_C; pfam07663
553482001131	HMMPfam hit to PF07663, Sorbitol phosphotransferase enzyme II C-t, score 2e-51
553482001132	2 transmembrane helices predicted for SEQ0283 by TMHMM2.0 at aa 185-207 and 222-244
553482001133	HMMPfam hit to PF03612, Sorbitol phosphotransferase enzyme II N-t, score 7.5e-111
553482001134	PTS system enzyme II sorbitol-specific factor; Region: EII-GUT; pfam03608
553482001135	HMMPfam hit to PF03608, PTS system enzyme II sorbitol-specific facto, score 3.8e-135
553482001136	3 transmembrane helices predicted for SEQ0284 by TMHMM2.0 at aa 25-47, 68-90 and 141-160
553482001137	Glucitol operon activator protein (GutM); Region: GutM; pfam06923
553482001138	HMMPfam hit to PF06923, Glucitol operon activator protein (GutM), score 1.4e-66
553482001139	1 transmembrane helix predicted for SEQ0285 by TMHMM2.0 at aa 4-23
553482001140	HTH domain; Region: HTH_11; pfam08279
553482001141	PRD domain; Region: PRD; pfam00874
553482001142	PTS_IIB_bgl_like: the PTS (phosphotransferase system) IIB domain of a family of sensory systems composed of a membrane-bound sugar-sensor (similar to BglF) and a transcription antiterminator (similar to BglG) which regulate expression of genes involved...; Region: PTS_IIB_bgl_like; cd05568
553482001143	active site
553482001144	P-loop; other site
553482001145	phosphorylation site [posttranslational modification]
553482001146	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
553482001147	active site
553482001148	phosphorylation site [posttranslational modification]
553482001149	HMMPfam hit to PF00874, PRD domain, score 7.3e-12
553482001150	HMMPfam hit to PF05043, Mga helix-turn-helix domain, score 0.0025
553482001151	HMMPfam hit to PF08279, HTH domain, score 1.1e-09
553482001152	Predicted helix-turn-helix motif with score 1780.000, SD 5.25 at aa 73-94, sequence LVIDDLADEIGVSRSTINKDLK
553482001153	glucose-6-phosphate isomerase; Provisional; Region: pgi; PRK14097
553482001154	Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the first SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_1; cd05015
553482001155	active site
553482001156	dimer interface [polypeptide binding]; other site
553482001157	Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the second SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_2; cd05016
553482001158	dimer interface [polypeptide binding]; other site
553482001159	active site
553482001160	HMMPfam hit to PF00342, Phosphoglucose isomerase, score 1e-153
553482001161	PS00765 Phosphoglucose isomerase signature 1.
553482001162	bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase; Provisional; Region: glmU; PRK14354
553482001163	N-terminal domain of bacterial GlmU; Region: GT2_GlmU_N_bac; cd02540
553482001164	Substrate binding site; other site
553482001165	Mg++ binding site; other site
553482001166	N-acetyl-glucosamine-1-phosphate uridyltransferase (GlmU), C-terminal left-handed beta-helix (LbH) acetyltransferase domain: GlmU is also known as UDP-N-acetylglucosamine pyrophosphorylase. It is a bifunctional bacterial enzyme that catalyzes two...; Region: LbH_GlmU_C; cd03353
553482001167	active site
553482001168	substrate binding site [chemical binding]; other site
553482001169	CoA binding site [chemical binding]; other site
553482001170	HMMPfam hit to PF00132, Bacterial transferase hexapeptide (th, score 14
553482001171	HMMPfam hit to PF00132, Bacterial transferase hexapeptide (th, score 1.2
553482001172	HMMPfam hit to PF00132, Bacterial transferase hexapeptide (th, score 36
553482001173	HMMPfam hit to PF00132, Bacterial transferase hexapeptide (th, score 42
553482001174	HMMPfam hit to PF00132, Bacterial transferase hexapeptide (th, score 0.99
553482001175	HMMPfam hit to PF00132, Bacterial transferase hexapeptide (th, score 9.6
553482001176	HMMPfam hit to PF00132, Bacterial transferase hexapeptide (th, score 4.2
553482001177	HMMPfam hit to PF00483, Nucleotidyl transferase, score 1.6e-10
553482001178	Prokaryotic UGPase catalyses the synthesis of UDP-glucose; Region: UGPase_prokaryotic; cd02541
553482001179	dTDP-glucose pyrophosphorylase [Cell envelope biogenesis, outer membrane]; Region: RfbA; COG1209
553482001180	active site
553482001181	tetramer interface; other site
553482001182	HMMPfam hit to PF00483, Nucleotidyl transferase, score 2.1e-18
553482001183	NAD(P)H-dependent glycerol-3-phosphate dehydrogenase; Validated; Region: gpsA; PRK00094
553482001184	NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; Region: NAD_Gly3P_dh_N; pfam01210
553482001185	NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus; Region: NAD_Gly3P_dh_C; pfam07479
553482001186	HMMPfam hit to PF07479, NAD-dependent glycerol-3-phosphate deh, score 1.2e-70
553482001187	HMMPfam hit to PF01210, NAD-dependent glycerol-3-phosphate deh, score 1.4e-80
553482001188	HMMPfam hit to PF02558, Ketopantoate reductase PanE/ApbA, score 0.00046
553482001189	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
553482001190	MarR family; Region: MarR_2; pfam12802
553482001191	HMMPfam hit to PF01047, MarR family, score 2.4e-13
553482001192	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
553482001193	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
553482001194	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
553482001195	Walker A/P-loop; other site
553482001196	ATP binding site [chemical binding]; other site
553482001197	Q-loop/lid; other site
553482001198	ABC transporter signature motif; other site
553482001199	Walker B; other site
553482001200	D-loop; other site
553482001201	H-loop/switch region; other site
553482001202	7 transmembrane helices predicted for SEQ0292 by TMHMM2.0 at aa 12-34, 52-74, 95-114, 124-146, 153-175, 235-257 and 264-286
553482001203	HMMPfam hit to PF00664, ABC transporter transmembrane region, score 4.4e-21
553482001204	HMMPfam hit to PF00005, ABC transporter, score 4.9e-50
553482001205	PS00017 ATP/GTP-binding site motif A (P-loop).
553482001206	PS00211 ABC transporters family signature.
553482001207	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
553482001208	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
553482001209	ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; Region: ABCC_MsbA; cd03251
553482001210	Walker A/P-loop; other site
553482001211	ATP binding site [chemical binding]; other site
553482001212	Q-loop/lid; other site
553482001213	ABC transporter signature motif; other site
553482001214	Walker B; other site
553482001215	D-loop; other site
553482001216	H-loop/switch region; other site
553482001217	HMMPfam hit to PF00664, ABC transporter transmembrane region, score 6e-27
553482001218	5 transmembrane helices predicted for SEQ0293 by TMHMM2.0 at aa 16-33, 82-104, 154-173, 178-200 and 257-279
553482001219	PS00046 Histone H2A signature.
553482001220	HMMPfam hit to PF00005, ABC transporter, score 1.2e-55
553482001221	PS00017 ATP/GTP-binding site motif A (P-loop).
553482001222	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1636
553482001223	HMMPfam hit to PF02677, Uncharacterized BCR, COG1636, score 1e-46
553482001224	Trimeric dUTP diphosphatases; Region: trimeric_dUTPase; cd07557
553482001225	trimer interface [polypeptide binding]; other site
553482001226	active site
553482001227	HMMPfam hit to PF00692, dUTPase, score 1.7e-17
553482001228	DNA repair protein RadA; Provisional; Region: PRK11823
553482001229	Sms (bacterial radA) DNA repair protein. This protein is not related to archael radA any more than is to other RecA-like NTPases. Sms has a role in recombination and recombinational repair and is responsible for the stabilization or processing of...; Region: Sms; cd01121
553482001230	Walker A motif/ATP binding site; other site
553482001231	ATP binding site [chemical binding]; other site
553482001232	Walker B motif; other site
553482001233	Subunit ChlI of Mg-chelatase; Region: ChlI; pfam13541
553482001234	PS00017 ATP/GTP-binding site motif A (P-loop).
553482001235	Carbonic anhydrases (CA) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism in which the nucleophilic attack of a zinc-bound hydroxide ion on carbon dioxide is followed by the regeneration of an...; Region: beta_CA_cladeD; cd03379
553482001236	active site clefts [active]
553482001237	zinc binding site [ion binding]; other site
553482001238	dimer interface [polypeptide binding]; other site
553482001239	HMMPfam hit to PF00484, Carbonic anhydrase, score 1.2e-13
553482001240	Uncharacterized conserved protein [Function unknown]; Region: COG2013
553482001241	HMMPfam hit to PF01987, Protein of unknown function DUF124, score 3.8e-84
553482001242	glutamyl-tRNA synthetase; Reviewed; Region: gltX; PRK01406
553482001243	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
553482001244	active site
553482001245	HIGH motif; other site
553482001246	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
553482001247	active site
553482001248	KMSKS motif; other site
553482001249	HMMPfam hit to PF00749, tRNA synthetases class I (E and Q), cata, score 4.3e-158
553482001250	PS00178 Aminoacyl-transfer RNA synthetases class-I signature.
553482001251	Predicted signal transduction protein with a C-terminal ATPase domain [Signal transduction mechanisms]; Region: COG2972
553482001252	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
553482001253	ATP binding site [chemical binding]; other site
553482001254	Mg2+ binding site [ion binding]; other site
553482001255	G-X-G motif; other site
553482001256	6 transmembrane helices predicted for SEQ0301 by TMHMM2.0 at aa 5-27, 45-67, 79-101, 116-138, 155-177 and 187-209
553482001257	HMMPfam hit to PF02518, Histidine kinase-, DNA gyrase B-, and HSP90, score 9.2e-07
553482001258	Predicted signal transduction protein with a C-terminal ATPase domain [Signal transduction mechanisms]; Region: COG2972
553482001259	6 transmembrane helices predicted for SEQ0302 by TMHMM2.0 at aa 7-29, 39-61, 74-96, 111-133, 150-172 and 182-199
553482001260	Response regulator of the LytR/AlgR family [Transcription / Signal transduction mechanisms]; Region: LytT; COG3279
553482001261	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
553482001262	active site
553482001263	phosphorylation site [posttranslational modification]
553482001264	intermolecular recognition site; other site
553482001265	dimerization interface [polypeptide binding]; other site
553482001266	LytTr DNA-binding domain; Region: LytTR; pfam04397
553482001267	HMMPfam hit to PF00072, Response regulator receiver domain, score 5.4e-07
553482001268	HMMPfam hit to PF04397, LytTr DNA-binding domain, score 6.3e-26
553482001269	ribonuclease P; Reviewed; Region: rnpA; PRK00499
553482001270	HMMPfam hit to PF00825, Ribonuclease P, score 4.8e-28
553482001271	Preprotein translocase subunit YidC [Intracellular trafficking and secretion]; Region: YidC; COG0706
553482001272	membrane protein insertase, YidC/Oxa1 family, C-terminal domain; Region: yidC_oxa1_cterm; TIGR03592
553482001273	5 transmembrane helices predicted for SEQ0305 by TMHMM2.0 at aa 13-32, 52-74, 129-151, 171-193 and 206-228
553482001274	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482001275	HMMPfam hit to PF02096, 60Kd inner membrane protein, score 4.4e-56
553482001276	Predicted RNA-binding protein [General function prediction only]; Region: Jag; COG1847
553482001277	jag_K homology RNA-binding domain. The KH domain is found in proteins homologous to the Bacillus subtilis protein Jag, which is associated with SpoIIIJ and is necessary for the third stage of sporulation.  The KH motif is a beta-alpha-alpha-beta-beta...; Region: jag_KH; cd02414
553482001278	G-X-X-G motif; other site
553482001279	R3H domain found in proteins homologous to Bacillus subtilus Jag, which is associated with SpoIIIJ. SpoIIIJ is necessary for the third stage of sporulation. The name of the R3H domain comes from the characteristic spacing of the most conserved arginine...; Region: R3H_jag; cd02644
553482001280	RxxxH motif; other site
553482001281	HMMPfam hit to PF01424, R3H domain, score 1.6e-11
553482001282	gene remnant. Similar to an internal region of Streptococcus thermophilus transposase Tnp1193 UniProt:Q5LYW0 (EMBL:CP000024 (448 aa) fasta scores: E()=1.9e-05, 45.333% id in 75 aa
553482001283	LXG domain of WXG superfamily; Region: LXG; pfam04740
553482001284	Possible gene remnant
553482001285	Nicotine adenine dinucleotide glycohydrolase (NADase); Region: NADase_NGA; pfam07461
553482001286	PS00017 ATP/GTP-binding site motif A (P-loop).
553482001287	CDS contains a nonsense mutation (ochre) after codon 109
553482001288	N-acetylmannosamine-6-phosphate epimerase (NanE) converts N-acetylmannosamine-6-phosphate to N-acetylglucosamine-6-phosphate. This reaction is part of the pathway that allows the usage of sialic acid as a carbohydrate source. Sialic acids are a family of...; Region: NanE; cd04729
553482001289	N-acetylmannosamine-6-phosphate 2-epimerase; Provisional; Region: PRK01130
553482001290	putative active site cavity [active]
553482001291	HMMPfam hit to PF04131, N-acetylmannosamine-6-phosphate epi, score 5e-125
553482001292	PTS system, glucose-specific IIBC component; Region: PTS-II-BC-glcB; TIGR02002
553482001293	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
553482001294	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cl00164
553482001295	active site turn [active]
553482001296	phosphorylation site [posttranslational modification]
553482001297	HMMPfam hit to PF02378, Phosphotransferase system, EIIC, score 1.2e-95
553482001298	10 transmembrane helices predicted for SEQ0316 by TMHMM2.0 at aa 12-34, 49-81, 88-110, 115-134, 155-177, 192-214, 263-285, 315-337, 344-366 and 371-393
553482001299	HMMPfam hit to PF00367, phosphotransferase system, EIIB, score 5.5e-14
553482001300	PS01035 PTS EIIB domains cysteine phosphorylation site signature.
553482001301	Phosphotransferase system IIA components [Carbohydrate transport and metabolism]; Region: NagE; COG2190
553482001302	HPr interaction site; other site
553482001303	glycerol kinase (GK) interaction site [polypeptide binding]; other site
553482001304	active site
553482001305	phosphorylation site [posttranslational modification]
553482001306	HMMPfam hit to PF00358, phosphoenolpyruvate-dependent sugar phosph, score 3.1e-48
553482001307	PS00371 PTS EIIA domains phosphorylation site signature 1.
553482001308	Helix-turn-helix domain; Region: HTH_28; pfam13518
553482001309	Winged helix-turn helix; Region: HTH_29; pfam13551
553482001310	Homeodomain-like domain; Region: HTH_32; pfam13565
553482001311	Integrase core domain; Region: rve; pfam00665
553482001312	HMMPfam hit to PF00665, Integrase core domain, score 6.4e-17
553482001313	PS00017 ATP/GTP-binding site motif A (P-loop).
553482001314	50S ribosomal protein L34; Reviewed; Region: rpmH; PRK00399
553482001315	PS00784 Ribosomal protein L34 signature.
553482001316	CDS contains a nonsense mutation (amber) after codon 144. Similar to Streptococcus pyogenes serotype M3 N-acetylmannosamine-6-phosphate 2-epimerase NanE UniProt:Q8K8P4 (EMBL:AE014074 (234 aa) fasta scores: E()=9.5e-62, 76.923% id in 234 aa
553482001317	HMMPfam hit to PF04131, N-acetylmannosamine-6-phosphate epi, score 1.4e-118
553482001318	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
553482001319	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
553482001320	HMMPfam hit to PF01547, Bacterial extracellular solute-binding prot, score 1.1e-27
553482001321	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482001322	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
553482001323	dimer interface [polypeptide binding]; other site
553482001324	conserved gate region; other site
553482001325	putative PBP binding loops; other site
553482001326	ABC-ATPase subunit interface; other site
553482001327	5 transmembrane helices predicted for SEQ0322 by TMHMM2.0 at aa 12-34, 70-92, 105-127, 158-180 and 264-286
553482001328	HMMPfam hit to PF00528, Binding-protein-dependent transport syst, score 1.7e-14
553482001329	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
553482001330	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
553482001331	dimer interface [polypeptide binding]; other site
553482001332	conserved gate region; other site
553482001333	putative PBP binding loops; other site
553482001334	ABC-ATPase subunit interface; other site
553482001335	PS00430 TonB-dependent receptor proteins signature 1.
553482001336	6 transmembrane helices predicted for SEQ0323 by TMHMM2.0 at aa 12-34, 76-98, 107-129, 134-156, 182-204 and 239-261
553482001337	HMMPfam hit to PF00528, Binding-protein-dependent transport syst, score 7.3e-24
553482001338	Domain of unknown function (DUF386); Region: DUF386; cl01047
553482001339	HMMPfam hit to PF04074, Domain of unknown function (DUF386), score 2e-39
553482001340	Protein of unknown function, DUF624; Region: DUF624; pfam04854
553482001341	5 transmembrane helices predicted for SEQ0325 by TMHMM2.0 at aa 26-48, 82-104, 117-139, 154-176 and 183-205
553482001342	HMMPfam hit to PF04854, Protein of unknown function, DUF624, score 1.6e-07
553482001343	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482001344	Dihydrodipicolinate synthase/N-acetylneuraminate lyase [Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: DapA; COG0329
553482001345	Class I aldolases; Region: Aldolase_Class_I; cl17187
553482001346	catalytic residue [active]
553482001347	HMMPfam hit to PF00701, Dihydrodipicolinate synthetase family, score 8e-35
553482001348	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482001349	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
553482001350	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
553482001351	nucleotide binding site [chemical binding]; other site
553482001352	HMMPfam hit to PF00480, ROK family, score 8.8e-27
553482001353	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482001354	gene remnant. Similar to the N-terminal region of Streptococcus suis acetyl xylan esterase UniProt:Q8RR40 (EMBL:AB071365 (323 aa) fasta scores: E()=8.5e-20, 55.319% id in 94 aa
553482001355	Transcriptional regulators [Transcription]; Region: RpiR; COG1737
553482001356	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
553482001357	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
553482001358	putative active site [active]
553482001359	HMMPfam hit to PF01380, SIS domain, score 1.9e-11
553482001360	HMMPfam hit to PF01418, Helix-turn-helix domain, rpiR family, score 0.0006
553482001361	TatD like proteins;  E.coli TatD is a cytoplasmic protein, shown to have magnesium dependent DNase activity; Region: TatD_DNAse; cd01310
553482001362	Predicted metal-dependent hydrolases with the TIM-barrel fold [General function prediction only]; Region: COG1099
553482001363	active site
553482001364	HMMPfam hit to PF01026, TatD related DNase, score 1.8e-122
553482001365	PS01137 Uncharacterized protein family UPF0006 signature 1.
553482001366	PS01091 Uncharacterized protein family UPF0006 signature 3.
553482001367	ribonuclease M5; Region: 5S_RNA_mat_M5; TIGR00334
553482001368	TOPRIM_ RNase M5_like: The topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain found in Ribonuclease M5: (RNase M5) and other small primase-like proteins from bacteria and archaea.  RNase M5 catalyzes the maturation of 5S rRNA in low...; Region: TOPRIM_RNase_M5_like; cd01027
553482001369	putative active site [active]
553482001370	putative metal binding site [ion binding]; other site
553482001371	Domain of unknown function (DUF4093); Region: DUF4093; pfam13331
553482001372	HMMPfam hit to PF01751, Toprim domain, score 2.7e-07
553482001373	16S ribosomal RNA methyltransferase KsgA/Dim1 family protein; Reviewed; Region: ksgA; PRK00274
553482001374	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
553482001375	S-adenosylmethionine binding site [chemical binding]; other site
553482001376	HMMPfam hit to PF00398, Ribosomal RNA adenine dimethylase, score 7.8e-77
553482001377	PS01131 Ribosomal RNA adenine dimethylases signature.
553482001378	GTPase RsgA; Reviewed; Region: PRK00098
553482001379	S1_YloQ_GTPase: YloQ GTase family (also known as YjeQ and CpgA), S1-like RNA-binding domain. Proteins in the YloQ GTase family bind the ribosome and have GTPase activity. The precise role of this family is unknown. The protein structure is composed of...; Region: S1_YloQ_GTPase; cd04466
553482001380	RNA binding site [nucleotide binding]; other site
553482001381	homodimer interface [polypeptide binding]; other site
553482001382	Ribosomal interacting GTPase YjeQ/EngC, a circularly permuted subfamily of the Ras GTPases; Region: YjeQ_EngC; cd01854
553482001383	GTPase/Zn-binding domain interface [polypeptide binding]; other site
553482001384	GTP/Mg2+ binding site [chemical binding]; other site
553482001385	G4 box; other site
553482001386	G1 box; other site
553482001387	Switch I region; other site
553482001388	G2 box; other site
553482001389	G3 box; other site
553482001390	Switch II region; other site
553482001391	HMMPfam hit to PF03193, Protein of unknown function, DUF258, score 9.8e-153
553482001392	PS00017 ATP/GTP-binding site motif A (P-loop).
553482001393	Pentose-5-phosphate-3-epimerase [Carbohydrate transport and metabolism]; Region: Rpe; COG0036
553482001394	Ribulose-5-phosphate 3-epimerase (RPE). This enzyme catalyses the interconversion of D-ribulose 5-phosphate (Ru5P) into D-xylulose 5-phosphate, as part of the Calvin cycle (reductive pentose phosphate pathway) in chloroplasts and in the oxidative pentose...; Region: RPE; cd00429
553482001395	substrate binding site [chemical binding]; other site
553482001396	hexamer interface [polypeptide binding]; other site
553482001397	metal binding site [ion binding]; metal-binding site
553482001398	HMMPfam hit to PF00834, Ribulose-phosphate 3 epimerase family, score 1.6e-107
553482001399	HMMPfam hit to PF00215, Orotidine 5'-phosphate decarboxylase /, score 0.002
553482001400	PS01085 Ribulose-phosphate 3-epimerase family signature 1.
553482001401	PS01086 Ribulose-phosphate 3-epimerase family signature 2.
553482001402	Thiamine pyrophosphokinase [Coenzyme metabolism]; Region: THI80; COG1564
553482001403	Thiamine pyrophosphokinase; Region: TPK; cd07995
553482001404	active site
553482001405	dimerization interface [polypeptide binding]; other site
553482001406	thiamine binding site [chemical binding]; other site
553482001407	HMMPfam hit to PF04263, Thiamin pyrophosphokinase, catalytic d, score 5.7e-43
553482001408	HMMPfam hit to PF04265, Thiamin pyrophosphokinase, vitamin B1, score 1.7e-19
553482001409	Predicted nuclease of restriction endonuclease-like fold, RmuC family [General function prediction only]; Region: COG1322
553482001410	RmuC family; Region: RmuC; pfam02646
553482001411	1 transmembrane helix predicted for SEQ0336 by TMHMM2.0 at aa 3-22
553482001412	HMMPfam hit to PF02646, RmuC family, score 5.7e-138
553482001413	Predicted HD-superfamily hydrolase [General function prediction only]; Region: COG3481
553482001414	YhaM_OBF_like: A subfamily of OB folds similar to that found in Bacillus subtilis YhaM and Staphylococcus aureus cmp-binding factor-1 (SaCBF1). Both these proteins are 3'-to-5'exoribonucleases. YhaM requires Mn2+ or Co2+ for activity and is...; Region: YhaM_OBF_like; cd04492
553482001415	generic binding surface II; other site
553482001416	generic binding surface I; other site
553482001417	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
553482001418	Zn2+ binding site [ion binding]; other site
553482001419	Mg2+ binding site [ion binding]; other site
553482001420	HMMPfam hit to PF01336, OB-fold nucleic acid binding domain, score 0.0052
553482001421	HMMPfam hit to PF01966, HD domain, score 4e-05
553482001422	pur operon repressor; Provisional; Region: PRK09213
553482001423	Bacterial purine repressor, N-terminal; Region: PuR_N; pfam09182
553482001424	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
553482001425	active site
553482001426	HMMPfam hit to PF00156, Phosphoribosyl transferase domain, score 6.1e-17
553482001427	SEC10/PgrA surface exclusion domain; Region: Surf_Exclu_PgrA; TIGR04320
553482001428	S12-like family, 30S ribosomal protein S12 subfamily; S12 is located at the interface of the large and small ribosomal subunits of prokaryotes, chloroplasts and mitochondria, where it plays an important role in both tRNA and ribosomal subunit...; Region: Ribosomal_S12; cd03368
553482001429	S17 interaction site [polypeptide binding]; other site
553482001430	S8 interaction site; other site
553482001431	16S rRNA interaction site [nucleotide binding]; other site
553482001432	streptomycin interaction site [chemical binding]; other site
553482001433	23S rRNA interaction site [nucleotide binding]; other site
553482001434	aminoacyl-tRNA interaction site (A-site) [nucleotide binding]; other site
553482001435	HMMPfam hit to PF00164, Ribosomal protein S12, score 1e-64
553482001436	PS00055 Ribosomal protein S12 signature.
553482001437	30S ribosomal protein S7; Validated; Region: PRK05302
553482001438	HMMPfam hit to PF00177, Ribosomal protein S7p/S5e, score 2e-81
553482001439	PS00052 Ribosomal protein S7 signature.
553482001440	elongation factor G; Reviewed; Region: PRK00007
553482001441	Elongation factor G (EF-G) family involved in both the elongation and ribosome recycling phases of protein synthesis; Region: EF-G; cd01886
553482001442	G1 box; other site
553482001443	putative GEF interaction site [polypeptide binding]; other site
553482001444	GTP/Mg2+ binding site [chemical binding]; other site
553482001445	Switch I region; other site
553482001446	G2 box; other site
553482001447	G3 box; other site
553482001448	Switch II region; other site
553482001449	G4 box; other site
553482001450	G5 box; other site
553482001451	EFG_mtEFG_II: this subfamily represents the domain II of elongation factor G (EF-G) in bacteria and, the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2)_like proteins found in eukaryotes. During the process of peptide synthesis...; Region: EFG_mtEFG_II; cd04088
553482001452	EFG_mtEFG1_IV: domains similar to domain IV of the bacterial translational elongation factor (EF) EF-G. Included in this group is a domain of mitochondrial Elongation factor G1 (mtEFG1) proteins homologous to domain IV of EF-G. Eukaryotic cells harbor 2...; Region: EFG_mtEFG1_IV; cd01434
553482001453	EFG_mtEFG_C: domains similar to the C-terminal domain of the bacterial translational elongation factor (EF) EF-G.  Included in this group is the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2) proteins. Eukaryotic cells harbor 2...; Region: EFG_mtEFG_C; cd03713
553482001454	HMMPfam hit to PF00009, Elongation factor Tu GTP binding domain, score 7.1e-113
553482001455	PS00017 ATP/GTP-binding site motif A (P-loop).
553482001456	PS00301 GTP-binding elongation factors signature.
553482001457	HMMPfam hit to PF03144, Elongation factor Tu domain, score 2.3e-18
553482001458	HMMPfam hit to PF03764, Elongation factor G, domain IV, score 5.7e-67
553482001459	HMMPfam hit to PF00679, Elongation factor G C-terminus, score 1e-46
553482001460	Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase [Carbohydrate transport and metabolism]; Region: GapA; COG0057
553482001461	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Region: Gp_dh_N; smart00846
553482001462	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; pfam02800
553482001463	HMMPfam hit to PF00044, Glyceraldehyde 3-phosphate dehydrogenase, NA, score 1.5e-78
553482001464	PS00071 Glyceraldehyde 3-phosphate dehydrogenase active site.
553482001465	HMMPfam hit to PF02800, Glyceraldehyde 3-phosphate dehydrogenase, C-, score 2.5e-99
553482001466	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
553482001467	active site
553482001468	motif I; other site
553482001469	motif II; other site
553482001470	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482001471	phosphoglycerate kinase; Provisional; Region: pgk; PRK00073
553482001472	Phosphoglycerate kinase; Region: PGK; pfam00162
553482001473	substrate binding site [chemical binding]; other site
553482001474	hinge regions; other site
553482001475	ADP binding site [chemical binding]; other site
553482001476	catalytic site [active]
553482001477	HMMPfam hit to PF00162, Phosphoglycerate kinase, score 1.4e-179
553482001478	PS00111 Phosphoglycerate kinase signature.
553482001479	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
553482001480	4 transmembrane helices predicted for SEQ0349 by TMHMM2.0 at aa 21-43, 58-80, 87-109 and 114-136
553482001481	Helix-Turn-Helix DNA binding domain of GlnR-like transcription regulators; Region: HTH_GlnR-like; cd01105
553482001482	MerR HTH family regulatory protein; Region: MerR_1; pfam13411
553482001483	DNA binding residues [nucleotide binding]
553482001484	putative dimer interface [polypeptide binding]; other site
553482001485	HMMPfam hit to PF00376, MerR family regulatory protein, score 4.5e-10
553482001486	Glutamine synthetase [Amino acid transport and metabolism]; Region: GlnA; COG0174
553482001487	Glutamine synthetase, beta-Grasp domain; Region: Gln-synt_N; pfam03951
553482001488	Glutamine synthetase, catalytic domain; Region: Gln-synt_C; pfam00120
553482001489	HMMPfam hit to PF03951, Glutamine synthetase, beta-Grasp domain, score 3e-14
553482001490	PS00180 Glutamine synthetase signature 1.
553482001491	HMMPfam hit to PF00120, Glutamine synthetase, catalytic domain, score 2.2e-152
553482001492	ABC-type oligopeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: OppA; COG4166
553482001493	The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold; Region: PBP2_OppA; cd08504
553482001494	peptide binding site [polypeptide binding]; other site
553482001495	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482001496	HMMPfam hit to PF00496, Bacterial extracellular solute-binding prot, score 2.8e-76
553482001497	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
553482001498	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
553482001499	dimer interface [polypeptide binding]; other site
553482001500	conserved gate region; other site
553482001501	putative PBP binding loops; other site
553482001502	ABC-ATPase subunit interface; other site
553482001503	6 transmembrane helices predicted for SEQ0353 by TMHMM2.0 at aa 9-31, 94-116, 128-150, 165-184, 225-247 and 275-297
553482001504	HMMPfam hit to PF00528, Binding-protein-dependent transport syst, score 4.5e-49
553482001505	Predicted helix-turn-helix motif with score 1106.000, SD 2.95 at aa 200-221, sequence TDYIQLARAKGLTKRQVTRRHA
553482001506	oligopeptide ABC transporter permease OppC; Provisional; Region: PRK15406
553482001507	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
553482001508	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
553482001509	dimer interface [polypeptide binding]; other site
553482001510	conserved gate region; other site
553482001511	putative PBP binding loops; other site
553482001512	ABC-ATPase subunit interface; other site
553482001513	5 transmembrane helices predicted for SEQ0354 by TMHMM2.0 at aa 42-64, 142-164, 191-213, 253-275 and 307-329
553482001514	HMMPfam hit to PF00528, Binding-protein-dependent transport syst, score 1.6e-44
553482001515	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppD; COG0444
553482001516	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
553482001517	Walker A/P-loop; other site
553482001518	ATP binding site [chemical binding]; other site
553482001519	Q-loop/lid; other site
553482001520	ABC transporter signature motif; other site
553482001521	Walker B; other site
553482001522	D-loop; other site
553482001523	H-loop/switch region; other site
553482001524	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
553482001525	HMMPfam hit to PF00005, ABC transporter, score 3.9e-56
553482001526	PS00017 ATP/GTP-binding site motif A (P-loop).
553482001527	HMMPfam hit to PF08352, Oligopeptide/dipeptide transporter, C-termi, score 2.2e-27
553482001528	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppF; COG1124
553482001529	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
553482001530	Walker A/P-loop; other site
553482001531	ATP binding site [chemical binding]; other site
553482001532	Q-loop/lid; other site
553482001533	ABC transporter signature motif; other site
553482001534	Walker B; other site
553482001535	D-loop; other site
553482001536	H-loop/switch region; other site
553482001537	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; pfam08352
553482001538	HMMPfam hit to PF00005, ABC transporter, score 2.2e-61
553482001539	PS00017 ATP/GTP-binding site motif A (P-loop).
553482001540	PS00211 ABC transporters family signature.
553482001541	HMMPfam hit to PF08352, Oligopeptide/dipeptide transporter, C-termi, score 2.3e-08
553482001542	mRNA degradation ribonucleases J1/J2 (metallo-beta-lactamase superfamily) [Translation, ribosomal structure and biogenesis; Replication, recombination and repair]; Region: COG0595
553482001543	Metallo-beta-lactamase superfamily; Region: Lactamase_B; pfam00753
553482001544	RNA-metabolising metallo-beta-lactamase; Region: RMMBL; pfam07521
553482001545	HMMPfam hit to PF07521, RNA-metabolising metallo-beta-lactamase, score 1.4e-14
553482001546	PS01292 Uncharacterized protein family UPF0036 signature
553482001547	hypothetical protein; Provisional; Region: PRK13667
553482001548	HMMPfam hit to PF07288, Protein of unknown function (DUF1447), score 5.9e-50
553482001549	tRNA threonylcarbamoyl adenosine modification protein YeaZ; Region: T6A_YeaZ; TIGR03725
553482001550	Glycoprotease family; Region: Peptidase_M22; pfam00814
553482001551	HMMPfam hit to PF00814, Glycoprotease family, score 2.3e-54
553482001552	ribosomal-protein-alanine acetyltransferase; Region: rimI; TIGR01575
553482001553	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
553482001554	Coenzyme A binding pocket [chemical binding]; other site
553482001555	HMMPfam hit to PF00583, Acetyltransferase (GNAT) family, score 7.6e-15
553482001556	UGMP family protein; Validated; Region: PRK09604
553482001557	Inactive homolog of metal-dependent proteases, putative molecular chaperone [Posttranslational modification, protein turnover, chaperones]; Region: COG1214; cl17884
553482001558	Carbamoyltransferase; Region: CmcH_NodU; pfam02543
553482001559	HMMPfam hit to PF00814, Glycoprotease family, score 1.2e-76
553482001560	Uncharacterized conserved protein [Function unknown]; Region: COG1434
553482001561	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259
553482001562	putative active site [active]
553482001563	5 transmembrane helices predicted for SEQ0362 by TMHMM2.0 at aa 12-34, 49-71, 84-106, 126-148 and 304-326
553482001564	HMMPfam hit to PF02698, DUF218 domain, score 7.9e-48
553482001565	30S ribosomal protein S14; Reviewed; Region: rpsN; PRK08881
553482001566	HMMPfam hit to PF00253, Ribosomal protein S14p/S29e, score 2.1e-17
553482001567	HI0933-like protein; Region: HI0933_like; pfam03486
553482001568	Chromate resistance exported protein; Region: Chrome_Resist; cl01744
553482001569	HMMPfam hit to PF03486, HI0933-like protein, score 6e-207
553482001570	HMMPfam hit to PF00890, FAD binding domain, score 0.0042
553482001571	HMMPfam hit to PF07992, Pyridine nucleotide-disulphide oxidored, score 0.00028
553482001572	HMMPfam hit to PF01266, FAD dependent oxidoreductase, score 0.00026
553482001573	HTH domain; Region: HTH_11; cl17392
553482001574	Predicted helix-turn-helix motif with score 1868.000, SD 5.55 at aa 22-43, sequence KTVSELADILGVSRQAVNNRVK
553482001575	HMMPfam hit to PF04394, Protein of unknown function, DUF536, score 5e-14
553482001576	DNA polymerase III, epsilon subunit and related 3'-5' exonucleases [DNA replication, recombination, and repair]; Region: DnaQ; COG0847
553482001577	DEDDh 3'-5' exonuclease domain family; Region: DEDDh; cd06127
553482001578	active site
553482001579	catalytic site [active]
553482001580	substrate binding site [chemical binding]; other site
553482001581	HMMPfam hit to PF00929, Exonuclease, score 3.2e-14
553482001582	Predicted transcriptional regulators [Transcription]; Region: SoxR; COG0789
553482001583	Helix-Turn-Helix DNA binding domain of the transcription regulators TipAL, Mta, and SkgA; Region: HTH_TipAL-Mta; cd01106
553482001584	DNA binding residues [nucleotide binding]
553482001585	dimer interface [polypeptide binding]; other site
553482001586	Predicted helix-turn-helix motif with score 1629.000, SD 4.74 at aa 5-26, sequence YSTGELAKAAGVTVRTVQYYDK
553482001587	HMMPfam hit to PF00376, MerR family regulatory protein, score 2.7e-12
553482001588	2 transmembrane helices predicted for SEQ0367 by TMHMM2.0 at aa 143-165 and 169-188
553482001589	hypothetical protein; Validated; Region: PRK00153
553482001590	HMMPfam hit to PF02575, Uncharacterised BCR, YbaB family COG0718, score 1.9e-38
553482001591	PS00017 ATP/GTP-binding site motif A (P-loop).
553482001592	1 transmembrane helix predicted for SEQ0369 by TMHMM2.0 at aa 21-43
553482001593	HMMPfam hit to PF00072, Response regulator receiver domain, score 2.1e-39
553482001594	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
553482001595	Helix-turn-helix domain; Region: HTH_28; pfam13518
553482001596	Predicted helix-turn-helix motif with score 1140.000, SD 3.07 at aa 19-40, sequence KSIKCLSEKFSIAESDLKYMIR
553482001597	HMMPfam hit to PF01527, Transposase, score 0.00062
553482001598	HMMPfam hit to PF02178, no description, score 0.21
553482001599	putative transposase OrfB; Reviewed; Region: PHA02517
553482001600	HTH-like domain; Region: HTH_21; pfam13276
553482001601	Integrase core domain; Region: rve; pfam00665
553482001602	Integrase core domain; Region: rve_2; pfam13333
553482001603	HMMPfam hit to PF00665, Integrase core domain, score 8.8e-38
553482001604	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
553482001605	HAMP domain; Region: HAMP; pfam00672
553482001606	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
553482001607	dimer interface [polypeptide binding]; other site
553482001608	phosphorylation site [posttranslational modification]
553482001609	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
553482001610	ATP binding site [chemical binding]; other site
553482001611	Mg2+ binding site [ion binding]; other site
553482001612	G-X-G motif; other site
553482001613	2 transmembrane helices predicted for SEQ0374 by TMHMM2.0 at aa 7-29 and 39-61
553482001614	HMMPfam hit to PF00672, HAMP domain, score 5.6e-08
553482001615	HMMPfam hit to PF00512, His Kinase A (phosphoacceptor) domain, score 1.6e-15
553482001616	HMMPfam hit to PF02518, Histidine kinase-, DNA gyrase B-, and HSP90, score 1.4e-37
553482001617	1 transmembrane helix predicted for SEQ0375 by TMHMM2.0 at aa 242-261
553482001618	HMMPfam hit to PF02986, Fibronectin binding repeat, score 1.8e-19
553482001619	HMMPfam hit to PF02986, Fibronectin binding repeat, score 1.4e-19
553482001620	HMMPfam hit to PF02986, Fibronectin binding repeat, score 8.8e-18
553482001621	HMMPfam hit to PF02986, Fibronectin binding repeat, score 8.8e-18
553482001622	HMMPfam hit to PF02986, Fibronectin binding repeat, score 6.7e-18
553482001623	HMMPfam hit to PF08341, Fibronectin-binding protein signal sequence, score 3.9e-27
553482001624	M protein trans-acting positive regulator (MGA) HTH domain; Region: HTH_Mga; pfam08280
553482001625	Mga helix-turn-helix domain; Region: Mga; pfam05043
553482001626	M protein trans-acting positive regulator (MGA) PRD domain; Region: PRD_Mga; pfam08270
553482001627	HMMPfam hit to PF08280, M protein trans-acting positive regulator (M, score 5e-06
553482001628	HMMPfam hit to PF05043, Mga helix-turn-helix domain, score 6.7e-16
553482001629	HMMPfam hit to PF08270, M protein trans-acting positive regulator (M, score 5.7e-32
553482001630	7 transmembrane helices predicted for SEQ0379 by TMHMM2.0 at aa 7-24, 34-56, 76-98, 113-132, 153-172, 177-194 and 201-223
553482001631	HMMPfam hit to PF02517, CAAX amino terminal protease family, score 7.3e-19
553482001632	CDS contains a nonsense mutation (opal) after codon 40. Similar to Streptococcus pyogenes serotype M1 repressor-phage associated (transcriptional regulator) UniProt:Q99Y57 (EMBL:AE006612 (124 aa) fasta scores: E()=2.5e-32, 85.593% id in 118 aa
553482001633	HMMPfam hit to PF01381, Helix-turn-helix, score 3.2e-07
553482001634	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
553482001635	non-specific DNA binding site [nucleotide binding]; other site
553482001636	salt bridge; other site
553482001637	sequence-specific DNA binding site [nucleotide binding]; other site
553482001638	HMMPfam hit to PF01381, Helix-turn-helix, score 6.8e-11
553482001639	Predicted helix-turn-helix motif with score 1876.000, SD 5.58 at aa 22-43, sequence KTQKELSALTGISVRTLARYEK
553482001640	Pyridoxine 5'-phosphate (PNP) oxidase-like proteins; Region: PNPOx_like; cl00381
553482001641	HMMPfam hit to PF01243, Pyridoxamine 5'-phosphate oxidase, score 6.2e-20
553482001642	x-prolyl-dipeptidyl aminopeptidase; Provisional; Region: PRK05371
553482001643	X-Prolyl dipeptidyl aminopeptidase PepX, N-terminal; Region: PepX_N; pfam09168
553482001644	X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain; Region: PepX_C; pfam08530
553482001645	HMMPfam hit to PF08530, X-Pro dipeptidyl-peptidase C-terminal n, score 6.6e-78
553482001646	HMMPfam hit to PF02129, X-Pro dipeptidyl-peptidase (S15 family), score 6.7e-151
553482001647	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
553482001648	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cl17320
553482001649	non-specific DNA interactions [nucleotide binding]; other site
553482001650	DNA binding site [nucleotide binding]
553482001651	sequence specific DNA binding site [nucleotide binding]; other site
553482001652	putative cAMP binding site [chemical binding]; other site
553482001653	HMMPfam hit to PF00325, Bacterial regulatory proteins, crp family, score 0.00017
553482001654	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
553482001655	Major Facilitator Superfamily; Region: MFS_1; pfam07690
553482001656	putative substrate translocation pore; other site
553482001657	12 transmembrane helices predicted for SEQ0385 by TMHMM2.0 at aa 13-35, 45-64, 76-98, 108-127, 134-156, 166-188, 209-231, 241-263, 276-295, 300-322, 335-357 and 372-389
553482001658	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482001659	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
553482001660	Ligand Binding Site [chemical binding]; other site
553482001661	HMMPfam hit to PF00582, Universal stress protein family, score 4.6e-21
553482001662	Major intrinsic protein (MIP) superfamily. Members of the MIP superfamily function as membrane channels that selectively transport water, small neutral molecules, and ions out of and between cells. The channel proteins share a common fold: the N-terminal...; Region: MIP; cd00333
553482001663	amphipathic channel; other site
553482001664	Asn-Pro-Ala signature motifs; other site
553482001665	HMMPfam hit to PF00230, Major intrinsic protein, score 2.6e-14
553482001666	6 transmembrane helices predicted for SEQ0387 by TMHMM2.0 at aa 5-27, 42-64, 71-93, 143-165, 196-218 and 259-281
553482001667	PS00221 MIP family signature.
553482001668	This domain superfamily is found in a variety of structurally related metalloproteins, including the type I extradiol dioxygenases, glyoxalase I and a group of antibiotic resistance proteins; Region: Glo_EDI_BRP_like; cl14632
553482001669	active site
553482001670	Beta-lactamase; Region: Beta-lactamase; pfam00144
553482001671	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
553482001672	HMMPfam hit to PF00144, Beta-lactamase, score 1.3e-52
553482001673	PS00146 Beta-lactamase class-A active site.
553482001674	formate acetyltransferase 1; Region: pyr_form_ly_1; TIGR01255
553482001675	Ribonucleotide reductase and Pyruvate formate lyase; Region: RNR_PFL; cl09939
553482001676	HMMPfam hit to PF01228, Glycine radical, score 3.1e-41
553482001677	PS00850 Glycine radical signature.
553482001678	HMMPfam hit to PF02901, Pyruvate formate lyase, score 0
553482001679	DNA Polymerase IV/Kappa; Region: PolY_Pol_IV_kappa; cd03586
553482001680	active site
553482001681	DNA polymerase IV; Validated; Region: PRK02406
553482001682	DNA binding site [nucleotide binding]
553482001683	HMMPfam hit to PF00817, impB/mucB/samB family, score 2.4e-103
553482001684	4 transmembrane helices predicted for SEQ0393 by TMHMM2.0 at aa 16-38, 69-91, 98-120 and 125-143
553482001685	helicase, putative, RecD/TraA family; Region: recD_rel; TIGR01448
553482001686	TENA/THI-4/PQQC family; Region: TENA_THI-4; cl15243
553482001687	AAA domain; Region: AAA_30; pfam13604
553482001688	Family description; Region: UvrD_C_2; pfam13538
553482001689	PS00017 ATP/GTP-binding site motif A (P-loop).
553482001690	signal peptidase I, bacterial type; Region: sigpep_I_bact; TIGR02227
553482001691	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
553482001692	Catalytic site [active]
553482001693	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
553482001694	HMMPfam hit to PF00717, Peptidase S24-like, score 1.3e-20
553482001695	PS00760 Signal peptidases I lysine active site.
553482001696	PS00501 Signal peptidases I serine active site.
553482001697	1 transmembrane helix predicted for SEQ0395 by TMHMM2.0 at aa 7-26
553482001698	ribonuclease HIII; Provisional; Region: PRK00996
553482001699	Domain of unknown function (DUF3378); Region: DUF3378; pfam11858
553482001700	bacterial Ribonuclease HIII-like; Region: RNase_HII_bacteria_HIII_like; cd06590
553482001701	RNA/DNA hybrid binding site [nucleotide binding]; other site
553482001702	active site
553482001703	HMMPfam hit to PF01351, Ribonuclease HII, score 4.7e-62
553482001704	Uncharacterized membrane protein, required for colicin V production [General function prediction only]; Region: CvpA; COG1286
553482001705	Colicin V production protein; Region: Colicin_V; pfam02674
553482001706	HMMPfam hit to PF02674, Colicin V production protein, score 2.4e-44
553482001707	4 transmembrane helices predicted for SEQ0398 by TMHMM2.0 at aa 2-19, 23-40, 80-102 and 122-144
553482001708	Mismatch repair ATPase (MutS family) [DNA replication, recombination, and repair]; Region: COG1193
553482001709	MutS domain III; Region: MutS_III; pfam05192
553482001710	ATP-binding cassette domain of MutS2; Region: ABC_MutS2; cd03280
553482001711	Walker A/P-loop; other site
553482001712	ATP binding site [chemical binding]; other site
553482001713	Q-loop/lid; other site
553482001714	ABC transporter signature motif; other site
553482001715	Walker B; other site
553482001716	D-loop; other site
553482001717	H-loop/switch region; other site
553482001718	Smr domain; Region: Smr; pfam01713
553482001719	HMMPfam hit to PF00488, MutS domain V, score 5.9e-15
553482001720	PS00017 ATP/GTP-binding site motif A (P-loop).
553482001721	HMMPfam hit to PF01713, Smr domain, score 4.1e-35
553482001722	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482001723	pyridine nucleotide-disulfide oxidoreductase; Provisional; Region: PRK07251
553482001724	ubiquinone biosynthesis hydroxylase family protein; Provisional; Region: PRK07608; cl17314
553482001725	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
553482001726	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
553482001727	HMMPfam hit to PF02852, Pyridine nucleotide-disulphide oxidored, score 2.9e-27
553482001728	HMMPfam hit to PF07992, Pyridine nucleotide-disulphide oxidored, score 3e-50
553482001729	HMMPfam hit to PF01134, Glucose inhibited division protein A, score 0.00044
553482001730	HMMPfam hit to PF00070, Pyridine nucleotide-disulphide oxidored, score 3.5e-28
553482001731	PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site.
553482001732	PS00017 ATP/GTP-binding site motif A (P-loop).
553482001733	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
553482001734	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
553482001735	catalytic residues [active]
553482001736	HMMPfam hit to PF00085, Thioredoxin, score 4.3e-32
553482001737	PS00194 Thioredoxin family active site.
553482001738	SH3 domain protein; Region: SH3_and_anchor; TIGR04211
553482001739	HMMPfam hit to PF00746, Gram positive anchor, score 0.00015
553482001740	PS00343 Gram-positive cocci surface proteins 'anchoring' hexapeptide.
553482001741	1 transmembrane helix predicted for SEQ0402 by TMHMM2.0 at aa 13-35
553482001742	A/G-specific DNA glycosylase [DNA replication, recombination, and repair]; Region: MutY; COG1194
553482001743	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
553482001744	minor groove reading motif; other site
553482001745	helix-hairpin-helix signature motif; other site
553482001746	substrate binding pocket [chemical binding]; other site
553482001747	active site
553482001748	DNA glycosylase (MutY in bacteria and hMYH in humans) is responsible for repairing misread  A*oxoG residues to C*G by removing the inappropriately paired adenine base from the DNA backbone. It belongs to the Nudix hydrolase superfamily and is important...; Region: DNA_Glycosylase_C; cd03431
553482001749	DNA binding and oxoG recognition site [nucleotide binding]
553482001750	HMMPfam hit to PF00633, Helix-hairpin-helix motif, score 2e-06
553482001751	gene remnant. Similar to the C-terminal region of Streptococcus mutans hypothetical protein UniProt:Q8DTE7 (EMBL:AE014133 (125 aa) fasta scores: E()=2.9e-12, 72.340% id in 47 aa
553482001752	30S ribosomal protein S6; Reviewed; Region: rpsF; PRK00453
553482001753	HMMPfam hit to PF01250, Ribosomal protein S6, score 2.7e-28
553482001754	Single-stranded DNA-binding protein [DNA replication, recombination, and repair]; Region: Ssb; COG0629
553482001755	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
553482001756	dimer interface [polypeptide binding]; other site
553482001757	ssDNA binding site [nucleotide binding]; other site
553482001758	tetramer (dimer of dimers) interface [polypeptide binding]; other site
553482001759	HMMPfam hit to PF00436, Single-strand binding protein family, score 4.7e-32
553482001760	PS00583 pfkB family of carbohydrate kinases signature 1.
553482001761	30S ribosomal protein S18; Reviewed; Region: rpsR; PRK00391
553482001762	HMMPfam hit to PF01084, Ribosomal protein S18, score 6.2e-34
553482001763	PS00057 Ribosomal protein S18 signature.
553482001764	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
553482001765	Helix-turn-helix domain; Region: HTH_28; pfam13518
553482001766	Predicted helix-turn-helix motif with score 1140.000, SD 3.07 at aa 19-40, sequence KSIKCLSEKFSIAESDLKYMIR
553482001767	HMMPfam hit to PF01527, Transposase, score 0.00062
553482001768	HMMPfam hit to PF02178, no description, score 0.21
553482001769	putative transposase OrfB; Reviewed; Region: PHA02517
553482001770	HTH-like domain; Region: HTH_21; pfam13276
553482001771	Integrase core domain; Region: rve; pfam00665
553482001772	Integrase core domain; Region: rve_2; pfam13333
553482001773	HMMPfam hit to PF00665, Integrase core domain, score 1.1e-37
553482001774	Protein of unknown function (DUF1129); Region: DUF1129; cl11555
553482001775	HMMPfam hit to PF06570, Protein of unknown function (DUF1129), score 2.5e-135
553482001776	4 transmembrane helices predicted for SEQ0414 by TMHMM2.0 at aa 84-106, 116-138, 151-173 and 183-202
553482001777	Mg2+ and Co2+ transporters [Inorganic ion transport and metabolism]; Region: CorA; COG0598
553482001778	uncharacterized bacterial subfamily of the Escherichia coli CorA-Salmonella typhimurium ZntB family; Region: EcCorA_ZntB-like_u2; cd12827
553482001779	Cl binding site [ion binding]; other site
553482001780	oligomer interface [polypeptide binding]; other site
553482001781	HMMPfam hit to PF01544, CorA-like Mg2+ transporter protein, score 2.6e-07
553482001782	2 transmembrane helices predicted for SEQ0415 by TMHMM2.0 at aa 255-277 and 287-309
553482001783	excinuclease ABC subunit A; Reviewed; Region: uvrA; PRK00349
553482001784	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
553482001785	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
553482001786	ATP-binding cassette domain II of the excision repair protein UvrA; Region: ABC_UvrA_II; cd03271
553482001787	PS00017 ATP/GTP-binding site motif A (P-loop).
553482001788	PS00190 Cytochrome c family heme-binding site signature.
553482001789	PS00211 ABC transporters family signature.
553482001790	HMMPfam hit to PF00005, ABC transporter, score 6.5e-33
553482001791	PS00017 ATP/GTP-binding site motif A (P-loop).
553482001792	PS00190 Cytochrome c family heme-binding site signature.
553482001793	PS00211 ABC transporters family signature.
553482001794	Xaa-Pro aminopeptidase [Amino acid transport and metabolism]; Region: PepP; COG0006
553482001795	Creatinase/Prolidase N-terminal domain; Region: Creatinase_N; pfam01321
553482001796	Similar to Prolidase and Aminopeptidase P. The members of this subfamily presumably catalyse hydrolysis of Xaa-Pro dipeptides and/or release of any N-terminal amino acid, including proline, that is linked with proline; Region: APP-like; cd01092
553482001797	active site
553482001798	HMMPfam hit to PF00557, metallopeptidase family M24, score 3.4e-63
553482001799	PS00491 Aminopeptidase P and proline dipeptidase signature.
553482001800	Deoxycytidylate deaminase domain. Deoxycytidylate deaminase catalyzes the deamination of dCMP to dUMP, providing the nucleotide substrate for thymidylate synthase. The enzyme binds Zn++, which is required for catalytic activity. The activity of the...; Region: deoxycytidylate_deaminase; cd01286
553482001801	catalytic motif [active]
553482001802	Zn binding site [ion binding]; other site
553482001803	HMMPfam hit to PF00383, Cytidine and deoxycytidylate deaminas, score 1.2e-31
553482001804	PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature.
553482001805	Helix-turn-helix domain; Region: HTH_28; pfam13518
553482001806	Winged helix-turn helix; Region: HTH_29; pfam13551
553482001807	Homeodomain-like domain; Region: HTH_32; pfam13565
553482001808	Integrase core domain; Region: rve; pfam00665
553482001809	HMMPfam hit to PF00665, Integrase core domain, score 6.4e-17
553482001810	PS00017 ATP/GTP-binding site motif A (P-loop).
553482001811	elongation factor P; Validated; Region: PRK00529
553482001812	Elongation factor P (EF-P) KOW-like domain; Region: EFP_N; pfam08207
553482001813	S1_EF-P_repeat_1: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_1; cd04470
553482001814	RNA binding site [nucleotide binding]; other site
553482001815	S1_EF-P_repeat_2: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_2; cd05794
553482001816	RNA binding site [nucleotide binding]; other site
553482001817	HMMPfam hit to PF08207, Elongation factor P (EF-P) KOW-like domain, score 1.5e-18
553482001818	HMMPfam hit to PF01132, Elongation factor P (EF-P) OB domain, score 4.3e-12
553482001819	PS01275 Elongation factor P signature.
553482001820	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1302
553482001821	HMMPfam hit to PF03780, Protein of unknown function (DUF322), score 7.5e-41
553482001822	transcription antitermination protein NusB; Reviewed; Region: nusB; PRK00202
553482001823	putative RNA binding site [nucleotide binding]; other site
553482001824	HMMPfam hit to PF01029, NusB family, score 1.3e-29
553482001825	PS00339 Aminoacyl-transfer RNA synthetases class-II signature 2.
553482001826	CDS contains a nonsense mutation (ochre) in comparison to SZO16200
553482001827	CDS contains a nonsense mutation (opal) in comparison to SZO16190
553482001828	Transcriptional regulators [Transcription]; Region: PurR; COG1609
553482001829	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
553482001830	DNA binding site [nucleotide binding]
553482001831	domain linker motif; other site
553482001832	Ligand binding domain of the lacI-like transcription regulator from a novel metal-reducing bacterium Alkaliphilus Metalliredigens (strain Qymf) and its close homologs; Region: PBP1_Qymf_like; cd06291
553482001833	dimerization interface [polypeptide binding]; other site
553482001834	ligand binding site [chemical binding]; other site
553482001835	sodium binding site [ion binding]; other site
553482001836	HMMPfam hit to PF00532, Periplasmic binding proteins and sugar b, score 3.4e-05
553482001837	PS00017 ATP/GTP-binding site motif A (P-loop).
553482001838	HMMPfam hit to PF00356, Bacterial regulatory proteins, lacI fami, score 1.2e-10
553482001839	Predicted helix-turn-helix motif with score 1960.000, SD 5.86 at aa 3-24, sequence AKLTDVAALAGVSPTTVSRVIN
553482001840	PS00356 Bacterial regulatory proteins, lacI family signature.
553482001841	sucrose-6-phosphate hydrolase; Region: scrB_fam; TIGR01322
553482001842	Glycosyl hydrolase family 32, beta-fructosidases; Region: GH32_B_Fructosidase; cd08996
553482001843	substrate binding [chemical binding]; other site
553482001844	active site
553482001845	Glycosyl hydrolases family 32 C terminal; Region: Glyco_hydro_32C; pfam08244
553482001846	HMMPfam hit to PF08244, Glycosyl hydrolases family 32 C termi, score 2.2e-13
553482001847	HMMPfam hit to PF00251, Glycosyl hydrolases family 32 N termi, score 1.4e-127
553482001848	PTS system, sucrose-specific IIBC component; Region: PTS-II-BC-sucr; TIGR01996
553482001849	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
553482001850	active site turn [active]
553482001851	phosphorylation site [posttranslational modification]
553482001852	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
553482001853	Phosphotransferase system IIA components [Carbohydrate transport and metabolism]; Region: NagE; COG2190
553482001854	HPr interaction site; other site
553482001855	glycerol kinase (GK) interaction site [polypeptide binding]; other site
553482001856	active site
553482001857	phosphorylation site [posttranslational modification]
553482001858	HMMPfam hit to PF00367, phosphotransferase system, EIIB, score 9.1e-19
553482001859	PS01035 PTS EIIB domains cysteine phosphorylation site signature.
553482001860	HMMPfam hit to PF02378, Phosphotransferase system, EIIC, score 1.1e-45
553482001861	10 transmembrane helices predicted for SEQ0431 by TMHMM2.0 at aa 111-132, 152-174, 181-203, 213-235, 254-276, 291-313, 334-354, 364-386, 391-413 and 433-455
553482001862	PS00044 Bacterial regulatory proteins, lysR family signature.
553482001863	HMMPfam hit to PF00358, phosphoenolpyruvate-dependent sugar phosph, score 1.4e-66
553482001864	PS00371 PTS EIIA domains phosphorylation site signature 1.
553482001865	Endo-beta-N-acetylglucosaminidases are bacterial chitinases that hydrolyze the chitin core of various asparagine (N)-linked glycans and glycoproteins. The endo-beta-N-acetylglucosaminidases have a glycosyl hydrolase family 18 (GH18) catalytic domain; Region: GH18_EndoS-like; cd06542
553482001866	active site
553482001867	PS01095 Chitinases family 18 active site.
553482001868	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
553482001869	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
553482001870	nucleotide binding site [chemical binding]; other site
553482001871	HMMPfam hit to PF00480, ROK family, score 1.2e-69
553482001872	PS01125 ROK family signature.
553482001873	Phosphomannose isomerase [Carbohydrate transport and metabolism]; Region: ManA; COG1482
553482001874	mannose-6-phosphate isomerase, class I; Region: manA; TIGR00218
553482001875	HMMPfam hit to PF01238, Phosphomannose isomerase type I, score 7.5e-98
553482001876	preprotein translocase subunit SecA; Reviewed; Region: PRK12904
553482001877	SecA preprotein cross-linking domain; Region: SecA_PP_bind; smart00958
553482001878	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cl17351
553482001879	nucleotide binding region [chemical binding]; other site
553482001880	ATP-binding site [chemical binding]; other site
553482001881	SEC-C motif; Region: SEC-C; pfam02810
553482001882	HMMPfam hit to PF07517, SecA DEAD-like domain, score 1.7e-199
553482001883	HMMPfam hit to PF01043, SecA preprotein cross-linking domain, score 3.3e-61
553482001884	HMMPfam hit to PF00271, Helicase conserved C-terminal domain, score 0.015
553482001885	PS01312 Protein secA signatures.
553482001886	HMMPfam hit to PF07516, SecA Wing and Scaffold domain, score 7.9e-68
553482001887	HMMPfam hit to PF02810, SEC-C motif, score 3.7e-07
553482001888	PS00200 Rieske iron-sulfur protein signature 2.
553482001889	4'-phosphopantetheinyl transferase; Provisional; Region: acpS; PRK00070
553482001890	HMMPfam hit to PF01648, 4'-phosphopantetheinyl transferase superfami, score 1.2e-14
553482001891	alanine racemase; Reviewed; Region: alr; PRK00053
553482001892	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Alanine Racemase; Region: PLPDE_III_AR; cd00430
553482001893	active site
553482001894	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
553482001895	dimer interface [polypeptide binding]; other site
553482001896	substrate binding site [chemical binding]; other site
553482001897	catalytic residues [active]
553482001898	HMMPfam hit to PF01168, Alanine racemase, N-terminal domain, score 2.2e-93
553482001899	PS00395 Alanine racemase pyridoxal-phosphate attachment site.
553482001900	HMMPfam hit to PF00842, Alanine racemase, C-terminal domain, score 1e-66
553482001901	putative transposase OrfB; Reviewed; Region: PHA02517
553482001902	HTH-like domain; Region: HTH_21; pfam13276
553482001903	Integrase core domain; Region: rve; pfam00665
553482001904	Integrase core domain; Region: rve_2; pfam13333
553482001905	HMMPfam hit to PF00665, Integrase core domain, score 8.8e-38
553482001906	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
553482001907	Helix-turn-helix domain; Region: HTH_28; pfam13518
553482001908	HMMPfam hit to PF01527, Transposase, score 0.00062
553482001909	HMMPfam hit to PF02178, no description, score 0.21
553482001910	Predicted helix-turn-helix motif with score 1140.000, SD 3.07 at aa 19-40, sequence KSIKCLSEKFSIAESDLKYMIR
553482001911	Surface antigen [General function prediction only]; Region: COG3942
553482001912	CHAP domain; Region: CHAP; pfam05257
553482001913	HMMPfam hit to PF05257, CHAP domain, score 1.2e-45
553482001914	HMMPfam hit to PF07550, Protein of unknown function (DUF1533), score 0.00011
553482001915	HMMPfam hit to PF07550, Protein of unknown function (DUF1533), score 1.9e-13
553482001916	HMMPfam hit to PF05031, Iron Transport-associated domain, score 4.4e-06
553482001917	PS00018 EF-hand calcium-binding domain.
553482001918	HMMPfam hit to PF00560, Leucine Rich Repeat, score 0.25
553482001919	HMMPfam hit to PF00560, Leucine Rich Repeat, score 0.38
553482001920	HMMPfam hit to PF00560, Leucine Rich Repeat, score 1.3
553482001921	HMMPfam hit to PF00560, Leucine Rich Repeat, score 0.9
553482001922	HMMPfam hit to PF00560, Leucine Rich Repeat, score 1
553482001923	HMMPfam hit to PF00560, Leucine Rich Repeat, score 1.4
553482001924	HMMPfam hit to PF00560, Leucine Rich Repeat, score 1.6
553482001925	HMMPfam hit to PF05031, Iron Transport-associated domain, score 1.2e-30
553482001926	1 transmembrane helix predicted for SEQ0444 by TMHMM2.0 at aa 767-786
553482001927	Cell surface heme-binding protein Shp; Region: HemeBinding_Shp; pfam11545
553482001928	2 transmembrane helices predicted for SEQ0445 by TMHMM2.0 at aa 13-32 and 271-290
553482001929	heme ABC transporter, heme-binding protein isdE; Region: IsdE; TIGR03659
553482001930	Helical backbone metal receptor (TroA-like domain). These proteins have been shown to function in the ABC transport of ferric siderophores and metal ions such as Mn2+, Fe3+, Cu2+ and/or Zn2+.  Their ligand binding site is formed in the interface between...; Region: TroA-like; cl00262
553482001931	intersubunit interface [polypeptide binding]; other site
553482001932	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482001933	HMMPfam hit to PF01497, Periplasmic binding protein, score 3.5e-29
553482001934	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
553482001935	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
553482001936	ABC-ATPase subunit  interface; other site
553482001937	dimer interface [polypeptide binding]; other site
553482001938	putative PBP binding regions; other site
553482001939	9 transmembrane helices predicted for SEQ0447 by TMHMM2.0 at aa 21-43, 69-91, 103-122, 126-148, 155-177, 199-221, 249-271, 286-303 and 310-332
553482001940	HMMPfam hit to PF01032, FecCD transport family, score 1.1e-86
553482001941	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482001942	ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components [Inorganic ion transport and metabolism / Coenzyme metabolism]; Region: FepC; COG1120
553482001943	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
553482001944	Walker A/P-loop; other site
553482001945	ATP binding site [chemical binding]; other site
553482001946	Q-loop/lid; other site
553482001947	ABC transporter signature motif; other site
553482001948	Walker B; other site
553482001949	D-loop; other site
553482001950	H-loop/switch region; other site
553482001951	HMMPfam hit to PF00005, ABC transporter, score 6.7e-49
553482001952	PS00017 ATP/GTP-binding site motif A (P-loop).
553482001953	PS00211 ABC transporters family signature.
553482001954	ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components [Energy production and conversion / Posttranslational modification, protein turnover, chaperones]; Region: CydD; COG4988
553482001955	ATP-binding cassette domain of multidrug resistance protein-like transporters; Region: ABCC_MRP_Like; cd03228
553482001956	Walker A/P-loop; other site
553482001957	ATP binding site [chemical binding]; other site
553482001958	Q-loop/lid; other site
553482001959	ABC transporter signature motif; other site
553482001960	Walker B; other site
553482001961	D-loop; other site
553482001962	H-loop/switch region; other site
553482001963	5 transmembrane helices predicted for SEQ0449 by TMHMM2.0 at aa 29-51, 66-88, 143-165, 169-188 and 260-282
553482001964	PS00041 Bacterial regulatory proteins, araC family signature.
553482001965	HMMPfam hit to PF00005, ABC transporter, score 7.1e-40
553482001966	PS00017 ATP/GTP-binding site motif A (P-loop).
553482001967	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
553482001968	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
553482001969	ATP-binding cassette domain of multidrug resistance protein-like transporters; Region: ABCC_MRP_Like; cd03228
553482001970	Walker A/P-loop; other site
553482001971	ATP binding site [chemical binding]; other site
553482001972	Q-loop/lid; other site
553482001973	ABC transporter signature motif; other site
553482001974	Walker B; other site
553482001975	D-loop; other site
553482001976	H-loop/switch region; other site
553482001977	7 transmembrane helices predicted for SEQ0450 by TMHMM2.0 at aa 21-43, 56-78, 85-102, 135-157, 164-183, 248-270 and 277-299
553482001978	HMMPfam hit to PF00005, ABC transporter, score 2.8e-39
553482001979	PS00017 ATP/GTP-binding site motif A (P-loop).
553482001980	Hypothetical bacterial integral membrane protein (Trep_Strep); Region: Trep_Strep; pfam09605
553482001981	5 transmembrane helices predicted for SEQ0451 by TMHMM2.0 at aa 10-32, 39-61, 76-98, 111-133 and 164-186
553482001982	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482001983	ABC-type cobalt transport system, permease component CbiQ and related transporters [Inorganic ion transport and metabolism]; Region: CbiQ; COG0619
553482001984	HMMPfam hit to PF02361, Cobalt transport protein, score 4.7e-05
553482001985	4 transmembrane helices predicted for SEQ0452 by TMHMM2.0 at aa 20-42, 47-69, 76-98 and 113-131
553482001986	ABC-type cobalt transport system, ATPase component [Inorganic ion transport and metabolism]; Region: CbiO; COG1122
553482001987	First domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain1; cd03225
553482001988	Walker A/P-loop; other site
553482001989	ATP binding site [chemical binding]; other site
553482001990	Q-loop/lid; other site
553482001991	ABC transporter signature motif; other site
553482001992	Walker B; other site
553482001993	D-loop; other site
553482001994	H-loop/switch region; other site
553482001995	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
553482001996	Walker A/P-loop; other site
553482001997	ATP binding site [chemical binding]; other site
553482001998	ABC transporter; Region: ABC_tran; pfam00005
553482001999	Q-loop/lid; other site
553482002000	ABC transporter signature motif; other site
553482002001	Walker B; other site
553482002002	D-loop; other site
553482002003	H-loop/switch region; other site
553482002004	HMMPfam hit to PF00005, ABC transporter, score 4.8e-43
553482002005	PS00675 Sigma-54 interaction domain ATP-binding region A signature.
553482002006	PS00017 ATP/GTP-binding site motif A (P-loop).
553482002007	PS00211 ABC transporters family signature.
553482002008	HMMPfam hit to PF00005, ABC transporter, score 1.8e-30
553482002009	PS00017 ATP/GTP-binding site motif A (P-loop).
553482002010	PS00211 ABC transporters family signature.
553482002011	ATP-dependent DNA helicase RecG; Provisional; Region: PRK10917
553482002012	RecG_wedge_OBF: A subfamily of OB folds corresponding to the OB fold found in the N-terminal (wedge) domain of Escherichia coli RecG. RecG is a branched-DNA-specific helicase, which catalyzes the interconversion of a DNA replication fork to a...; Region: RecG_wedge_OBF; cd04488
553482002013	generic binding surface II; other site
553482002014	ssDNA binding site; other site
553482002015	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
553482002016	ATP binding site [chemical binding]; other site
553482002017	putative Mg++ binding site [ion binding]; other site
553482002018	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
553482002019	nucleotide binding region [chemical binding]; other site
553482002020	ATP-binding site [chemical binding]; other site
553482002021	HMMPfam hit to PF00270, DEAD/DEAH box helicase, score 2.4e-34
553482002022	PS00017 ATP/GTP-binding site motif A (P-loop).
553482002023	HMMPfam hit to PF00271, Helicase conserved C-terminal domain, score 1.9e-21
553482002024	Type II (periplasmic) bacterial L-asparaginase; Region: L-asparaginase_II; cd08964
553482002025	active site
553482002026	homotetramer interface [polypeptide binding]; other site
553482002027	homodimer interface [polypeptide binding]; other site
553482002028	HMMPfam hit to PF00710, Asparaginase, score 2.3e-142
553482002029	PS00144 Asparaginase / glutaminase active site signature 1.
553482002030	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
553482002031	haloacid dehalogenase-like hydrolase; Region: Hydrolase_3; pfam08282
553482002032	active site
553482002033	motif I; other site
553482002034	motif II; other site
553482002035	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cl17915
553482002036	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4696
553482002037	metal binding site [ion binding]; metal-binding site
553482002038	HMMPfam hit to PF05116, Sucrose-6F-phosphate phosphohydrolase, score 4.2e-05
553482002039	HMMPfam hit to PF00702, haloacid dehalogenase-like hydrolase, score 2.1e-10
553482002040	PS01228 Hypothetical cof family signature 1.
553482002041	HMMPfam hit to PF08282, haloacid dehalogenase-like hydrolase, score 2.3e-80
553482002042	Predicted helix-turn-helix motif with score 986.000, SD 2.55 at aa 71-92, sequence LTRDKVLYQNQLPKSTIYKIIR
553482002043	PS01229 Hypothetical cof family signature 2.
553482002044	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
553482002045	Ligand Binding Site [chemical binding]; other site
553482002046	HMMPfam hit to PF00582, Universal stress protein family, score 9.6e-21
553482002047	aminotransferase AlaT; Validated; Region: PRK09265
553482002048	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
553482002049	pyridoxal 5'-phosphate binding site [chemical binding]; other site
553482002050	homodimer interface [polypeptide binding]; other site
553482002051	catalytic residue [active]
553482002052	HMMPfam hit to PF00155, Aminotransferase class I and II, score 1.2e-45
553482002053	HMMPfam hit to PF01212, Beta-eliminating lyase, score 0.0012
553482002054	Pleiotropic transcriptional repressor [Transcription]; Region: CodY; COG4465
553482002055	CodY GAF-like domain; Region: CodY; pfam06018
553482002056	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
553482002057	dimerization interface [polypeptide binding]; other site
553482002058	putative Zn2+ binding site [ion binding]; other site
553482002059	putative DNA binding site [nucleotide binding]; other site
553482002060	HMMPfam hit to PF06018, CodY GAF-like domain, score 4.3e-121
553482002061	HMMPfam hit to PF08279, HTH domain, score 0.00042
553482002062	HMMPfam hit to PF08222, CodY helix-turn-helix domain, score 3.5e-38
553482002063	Predicted helix-turn-helix motif with score 1428.000, SD 4.05 at aa 205-226, sequence LTASVIADRIGITRSVIVNALR
553482002064	Isochorismatase family; Region: Isochorismatase; pfam00857
553482002065	Cysteine hydrolases; This family contains amidohydrolases, like CSHase (N-carbamoylsarcosine amidohydrolase), involved in creatine metabolism and nicotinamidase, converting nicotinamide to nicotinic acid and ammonia in the pyridine nucleotide cycle. It...; Region: cysteine_hydrolases; cd00431
553482002066	catalytic triad [active]
553482002067	conserved cis-peptide bond; other site
553482002068	HMMPfam hit to PF00857, Isochorismatase family, score 1e-16
553482002069	aspartyl/glutamyl-tRNA amidotransferase subunit C; Reviewed; Region: gatC; PRK00034
553482002070	HMMPfam hit to PF02686, Glu-tRNAGln amidotransferase C subunit, score 3.3e-14
553482002071	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases [Translation, ribosomal structure and biogenesis]; Region: GatA; COG0154
553482002072	aspartyl/glutamyl-tRNA amidotransferase subunit A; Reviewed; Region: gatA; PRK00012
553482002073	HMMPfam hit to PF01425, Amidase, score 1.4e-184
553482002074	aspartyl/glutamyl-tRNA amidotransferase subunit B; Validated; Region: gatB; PRK05477
553482002075	GatB/GatE catalytic domain; Region: GatB_N; pfam02934
553482002076	GatB domain; Region: GatB_Yqey; pfam02637
553482002077	HMMPfam hit to PF02934, PET112 family, N terminal region, score 1.5e-143
553482002078	HMMPfam hit to PF01162, PET112 family, C terminal region, score 2.8e-29
553482002079	HMMPfam hit to PF02637, GatB/Yqey domain, score 1.9e-58
553482002080	Carboxylate/Amino Acid/Amine Transporter; Region: 2A78; TIGR00950
553482002081	EamA-like transporter family; Region: EamA; pfam00892
553482002082	10 transmembrane helices predicted for SEQ0464 by TMHMM2.0 at aa 7-29, 33-55, 75-94, 99-118, 125-147, 152-174, 183-205, 215-237, 250-267 and 277-296
553482002083	HMMPfam hit to PF00892, Integral membrane protein DUF6, score 1.6e-12
553482002084	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482002085	HMMPfam hit to PF00892, Integral membrane protein DUF6, score 1.3e-16
553482002086	Predicted membrane protein [Function unknown]; Region: COG2261
553482002087	2 transmembrane helices predicted for SEQ0465 by TMHMM2.0 at aa 2-19 and 53-75
553482002088	HMMPfam hit to PF04226, Transglycosylase associated protein, score 1.8e-12
553482002089	KxYKxGKxW signal peptide; Region: KxYKxGKxW; TIGR03715
553482002090	1 transmembrane helix predicted for SEQ0466 by TMHMM2.0 at aa 17-39
553482002091	ACT domain proteins similar to the yet uncharacterized Streptococcus pneumoniae ACT domain protein; Region: ACT_1ZPV; cd04872
553482002092	HMMPfam hit to PF01842, ACT domain, score 0.0033
553482002093	Uncharacterized proteins with similarity to Ribonucleotide reductase and Pyruvate formate lyase; Region: RNR_PFL_like_DUF711; cd08025
553482002094	HMMPfam hit to PF05167, Uncharacterized ACR (DUF711), score 2.2e-270
553482002095	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
553482002096	catalytic core [active]
553482002097	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
553482002098	HMMPfam hit to PF00300, Phosphoglycerate mutase family, score 2.5e-37
553482002099	D-alanyl-D-alanine carboxypeptidase [Cell envelope biogenesis, outer membrane]; Region: VanY; COG1876
553482002100	D-alanyl-D-alanine carboxypeptidase; Region: VanY; pfam02557
553482002101	1 transmembrane helix predicted for SEQ0470 by TMHMM2.0 at aa 7-26
553482002102	HMMPfam hit to PF02557, D-alanyl-D-alanine carboxypeptidase, score 1.8e-50
553482002103	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase; Region: Glucosaminidase; cl17361
553482002104	1 transmembrane helix predicted for SEQ0471 by TMHMM2.0 at aa 7-29
553482002105	HMMPfam hit to PF01832, Mannosyl-glycoprotein endo-beta-N-ace, score 0.002
553482002106	heat-inducible transcription repressor; Provisional; Region: hrcA; PRK00082
553482002107	HMMPfam hit to PF01628, HrcA protein C terminal domain, score 1.8e-52
553482002108	HMMPfam hit to PF02809, no description, score 0.59
553482002109	GrpE; Region: GrpE; pfam01025
553482002110	GrpE is the adenine nucleotide exchange factor of DnaK (Hsp70)-type ATPases. The GrpE dimer binds to the ATPase domain of Hsp70 catalyzing the dissociation of ADP, which enables rebinding of ATP, one step in the Hsp70 reaction cycle in protein folding; Region: GrpE; cd00446
553482002111	dimer interface [polypeptide binding]; other site
553482002112	hsp70 (ATPase domain) interactions [polypeptide binding]; other site
553482002113	HMMPfam hit to PF01025, GrpE, score 2.9e-59
553482002114	PS01071 grpE protein signature.
553482002115	molecular chaperone DnaK; Provisional; Region: dnaK; PRK00290
553482002116	Nucleotide-binding domain of human HSPA9 and similar proteins; Region: HSPA9-Ssq1-like_NBD; cd10234
553482002117	nucleotide binding site [chemical binding]; other site
553482002118	NEF interaction site [polypeptide binding]; other site
553482002119	SBD interface [polypeptide binding]; other site
553482002120	HMMPfam hit to PF00012, Hsp70 protein, score 0
553482002121	PS00297 Heat shock hsp70 proteins family signature 1.
553482002122	PS00329 Heat shock hsp70 proteins family signature 2.
553482002123	PS01036 Heat shock hsp70 proteins family signature 3.
553482002124	chaperone protein DnaJ; Provisional; Region: PRK14276
553482002125	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
553482002126	HSP70 interaction site [polypeptide binding]; other site
553482002127	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cl03262
553482002128	substrate binding site [polypeptide binding]; other site
553482002129	Zinc finger domain of DnaJ and HSP40; Region: DnaJ_zf; cd10719
553482002130	Zn binding sites [ion binding]; other site
553482002131	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cd10747
553482002132	dimer interface [polypeptide binding]; other site
553482002133	HMMPfam hit to PF00226, DnaJ domain, score 6.7e-33
553482002134	PS00636 Nt-dnaJ domain signature.
553482002135	PS00225 Crystallins beta and gamma 'Greek key' motif signature.
553482002136	HMMPfam hit to PF00684, DnaJ central domain (4 repeats), score 2.7e-33
553482002137	PS00637 CXXCXGXG dnaJ domain signature.
553482002138	PS00190 Cytochrome c family heme-binding site signature.
553482002139	PS00190 Cytochrome c family heme-binding site signature.
553482002140	HMMPfam hit to PF01556, DnaJ C terminal region, score 2.5e-66
553482002141	enoyl-CoA hydratase; Provisional; Region: PRK07260
553482002142	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
553482002143	substrate binding site [chemical binding]; other site
553482002144	oxyanion hole (OAH) forming residues; other site
553482002145	trimer interface [polypeptide binding]; other site
553482002146	HMMPfam hit to PF00378, Enoyl-CoA hydratase/isomerase family, score 1.9e-23
553482002147	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
553482002148	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
553482002149	putative Zn2+ binding site [ion binding]; other site
553482002150	putative DNA binding site [nucleotide binding]; other site
553482002151	dimerization interface [polypeptide binding]; other site
553482002152	HMMPfam hit to PF03965, Penicillinase repressor, score 0.0016
553482002153	HMMPfam hit to PF01047, MarR family, score 2.9e-19
553482002154	Predicted helix-turn-helix motif with score 1065.000, SD 2.81 at aa 50-71, sequence VTPSDIARELMVTLGTVTTSLN
553482002155	PS00215 Mitochondrial energy transfer proteins signature.
553482002156	3-oxoacyl-(acyl carrier protein) synthase III; Reviewed; Region: PRK09352
553482002157	Ketoacyl-acyl carrier protein synthase III (KASIII) initiates the elongation in type II fatty acid synthase systems. It is found in bacteria and plants. Elongation of fatty acids in the type II systems occurs by Claisen condensation of malonyl-acyl...; Region: KAS_III; cd00830
553482002158	dimer interface [polypeptide binding]; other site
553482002159	active site
553482002160	CoA binding pocket [chemical binding]; other site
553482002161	HMMPfam hit to PF08545, 3-Oxoacyl-[acyl-carrier-protein (ACP)], score 7.3e-47
553482002162	HMMPfam hit to PF08541, 3-Oxoacyl-[acyl-carrier-protein (ACP)], score 5.3e-45
553482002163	acyl carrier protein; Provisional; Region: acpP; PRK00982
553482002164	HMMPfam hit to PF00550, Phosphopantetheine attachment site, score 5.1e-12
553482002165	putative enoyl-[acyl-carrier-protein] reductase II; Region: enACPred_II; TIGR03151
553482002166	2-Nitropropane dioxygenase (NPD), one of the nitroalkane oxidizing enzyme families, catalyzes oxidative denitrification of nitroalkanes to their corresponding carbonyl compounds and nitrites. NDP is a member of the NAD(P)H-dependent flavin oxidoreductase...; Region: NPD_like; cd04730
553482002167	FMN binding site [chemical binding]; other site
553482002168	substrate binding site [chemical binding]; other site
553482002169	putative catalytic residue [active]
553482002170	HMMPfam hit to PF03060, 2-nitropropane dioxygenase, score 1.3e-107
553482002171	PS00912 Dihydroorotate dehydrogenase signature 2.
553482002172	(acyl-carrier-protein) S-malonyltransferase [Lipid metabolism]; Region: FabD; COG0331
553482002173	malonyl CoA-acyl carrier protein transacylase; Region: fabD; TIGR00128
553482002174	HMMPfam hit to PF00698, Acyl transferase domain, score 2.4e-16
553482002175	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05557
553482002176	beta-Keto acyl carrier protein reductase (BKR), involved in Type II FAS, classical (c) SDRs; Region: BKR_SDR_c; cd05333
553482002177	NAD(P) binding site [chemical binding]; other site
553482002178	homotetramer interface [polypeptide binding]; other site
553482002179	homodimer interface [polypeptide binding]; other site
553482002180	active site
553482002181	HMMPfam hit to PF00106, short chain dehydrogenase, score 4e-47
553482002182	HMMPfam hit to PF07993, Male sterility protein, score 0.0008
553482002183	PS00061 Short-chain dehydrogenases/reductases family signature.
553482002184	PS00038 Myc-type, 'helix-loop-helix' dimerization domain signature.
553482002185	3-oxoacyl-(acyl carrier protein) synthase II; Reviewed; Region: PRK07314
553482002186	Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen...; Region: KAS_I_II; cd00834
553482002187	dimer interface [polypeptide binding]; other site
553482002188	active site
553482002189	HMMPfam hit to PF00109, Beta-ketoacyl synthase, N-terminal do, score 6.8e-65
553482002190	PS00606 Beta-ketoacyl synthases active site.
553482002191	PS00098 Thiolases acyl-enzyme intermediate signature.
553482002192	HMMPfam hit to PF02801, Beta-ketoacyl synthase, C-terminal do, score 6.3e-59
553482002193	acetyl-CoA carboxylase biotin carboxyl carrier protein subunit; Validated; Region: PRK06302
553482002194	The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850
553482002195	carboxyltransferase (CT) interaction site; other site
553482002196	biotinylation site [posttranslational modification]; other site
553482002197	HMMPfam hit to PF00364, Biotin-requiring enzyme, score 7.4e-25
553482002198	FabZ is a 17kD beta-hydroxyacyl-acyl carrier protein (ACP) dehydratase that primarily catalyzes the dehydration of beta-hydroxyacyl-ACP to trans-2-acyl-ACP, the third step in the elongation phase of the bacterial/ plastid, type II, fatty-acid...; Region: FabZ; cd01288
553482002199	HMMPfam hit to PF07977, FabA-like domain, score 1.5e-68
553482002200	acetyl-CoA carboxylase biotin carboxylase subunit; Validated; Region: PRK08591
553482002201	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
553482002202	ATP-grasp domain; Region: ATP-grasp_4; cl17255
553482002203	Biotin carboxylase C-terminal domain; Region: Biotin_carb_C; smart00878
553482002204	HMMPfam hit to PF00289, Carbamoyl-phosphate synthase L chain,, score 6.9e-43
553482002205	HMMPfam hit to PF02786, Carbamoyl-phosphate synthase L chain,, score 4.3e-95
553482002206	PS00866 Carbamoyl-phosphate synthase subdomain signature 1.
553482002207	PS00238 Visual pigments (opsins) retinal binding site.
553482002208	PS00867 Carbamoyl-phosphate synthase subdomain signature 2.
553482002209	HMMPfam hit to PF02785, Biotin carboxylase C-terminal domain, score 2.4e-53
553482002210	acetyl-CoA carboxylase subunit beta; Validated; Region: PRK05654
553482002211	malonate decarboxylase subunit beta; Reviewed; Region: PRK07189; cl17682
553482002212	acetyl-CoA carboxylase subunit alpha; Provisional; Region: PRK12319
553482002213	HMMPfam hit to PF03255, Acetyl co-enzyme A carboxylase carboxyltrans, score 7.3e-22
553482002214	seryl-tRNA synthetase; Provisional; Region: PRK05431
553482002215	Seryl-tRNA synthetase N-terminal domain; Region: Seryl_tRNA_N; pfam02403
553482002216	Seryl-tRNA synthetase (SerRS) class II core catalytic domain. SerRS is responsible for the attachment of serine to the 3' OH group of ribose of the appropriate tRNA. This domain It is primarily responsible for ATP-dependent formation of the enzyme...; Region: SerRS_core; cd00770
553482002217	dimer interface [polypeptide binding]; other site
553482002218	active site
553482002219	motif 1; other site
553482002220	motif 2; other site
553482002221	motif 3; other site
553482002222	HMMPfam hit to PF00587, tRNA synthetase class II core domain (G,, score 9.3e-70
553482002223	PS00179 Aminoacyl-transfer RNA synthetases class-II signature 1.
553482002224	HMMPfam hit to PF02403, Seryl-tRNA synthetase N-terminal domain, score 2.4e-44
553482002225	Predicted O-acyltransferase [General function prediction only]; Region: COG3274
553482002226	Acyltransferase family; Region: Acyl_transf_3; pfam01757
553482002227	9 transmembrane helices predicted for SEQ0490 by TMHMM2.0 at aa 31-53, 65-87, 102-124, 131-150, 165-183, 190-209, 213-235, 242-262 and 282-304
553482002228	Domain of unknown function (DUF956); Region: DUF956; cl01917
553482002229	HMMPfam hit to PF06115, Domain of unknown function (DUF956), score 2.8e-75
553482002230	Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IID [Carbohydrate transport and metabolism]; Region: ManZ; COG3716
553482002231	4 transmembrane helices predicted for SEQ0492 by TMHMM2.0 at aa 125-147, 181-203, 260-277 and 284-302
553482002232	PTS system mannose-specific transporter subunit IIC; Provisional; Region: PRK15065
553482002233	7 transmembrane helices predicted for SEQ0493 by TMHMM2.0 at aa 4-21, 33-55, 65-87, 99-121, 144-166, 187-206 and 221-243
553482002234	HMMPfam hit to PF03609, PTS system sorbose-specific iic component, score 2.2e-137
553482002235	PTS system mannose-specific transporter subunits IIAB; Provisional; Region: PRK15088
553482002236	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cd00006
553482002237	active pocket/dimerization site; other site
553482002238	active site
553482002239	phosphorylation site [posttranslational modification]
553482002240	PTS_IIB, PTS system, Mannose/sorbose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_man; cd00001
553482002241	active site
553482002242	phosphorylation site [posttranslational modification]
553482002243	HMMPfam hit to PF03830, PTS system sorbose subfamily IIB componen, score 7.2e-87
553482002244	HMMPfam hit to PF03610, PTS system fructose IIA component, score 9.2e-55
553482002245	CDS contains a frameshift after codon 128. Frameshift occurs at a poly T pentamer. Similar to Streptococcus pyogenes serotype M18 hypothetical protein Spym18_1809 UniProt:Q8NZP0 (EMBL:AE010088 (270 aa) fasta scores: E()=3.1e-86, 83.704% id in 270 aa
553482002246	HMMPfam hit to PF08282, haloacid dehalogenase-like hydrolase, score 5.2e-06
553482002247	Xanthine/uracil/vitamin C permease [Nucleotide transport and    metabolism]; Region: COG2252
553482002248	Predicted transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: COG1548; cl00668
553482002249	HMMPfam hit to PF00860, Permease family, score 3.8e-09
553482002250	10 transmembrane helices predicted for SEQ0497 by TMHMM2.0 at aa 20-42, 49-71, 91-113, 125-147, 196-218, 225-247, 257-276, 379-413, 433-455 and 468-485
553482002251	Predicted ATPase or kinase [General function prediction only]; Region: COG0802
553482002252	HMMPfam hit to PF02367, Uncharacterised P-loop hydrolase UPF0079, score 5.1e-39
553482002253	PS00017 ATP/GTP-binding site motif A (P-loop).
553482002254	putative acetyltransferase YhhY; Provisional; Region: PRK10140
553482002255	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
553482002256	Coenzyme A binding pocket [chemical binding]; other site
553482002257	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
553482002258	HMMPfam hit to PF00583, Acetyltransferase (GNAT) family, score 2.9e-11
553482002259	Transcriptional regulator [Transcription]; Region: LytR; COG1316
553482002260	1 transmembrane helix predicted for SEQ0500 by TMHMM2.0 at aa 7-29
553482002261	HMMPfam hit to PF03816, Cell envelope-related transcriptional a, score 5.6e-79
553482002262	Protein of unknown function (DUF1479); Region: DUF1479; pfam07350
553482002263	HINT (histidine triad nucleotide-binding protein) subgroup: Members of this CD belong to the superfamily of histidine triad hydrolases that act on alpha-phosphate of ribonucleotides. This subgroup includes members from all three forms of cellular life; Region: HINT_subgroup; cd01277
553482002264	HIT family signature motif; other site
553482002265	catalytic residue [active]
553482002266	HMMPfam hit to PF01230, HIT domain, score 1.7e-38
553482002267	ABC-type Na+ transport system, ATPase component [Energy production and conversion / Inorganic ion transport and metabolism]; Region: NatA; COG4555
553482002268	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
553482002269	Walker A/P-loop; other site
553482002270	ATP binding site [chemical binding]; other site
553482002271	Q-loop/lid; other site
553482002272	ABC transporter signature motif; other site
553482002273	Walker B; other site
553482002274	D-loop; other site
553482002275	H-loop/switch region; other site
553482002276	HMMPfam hit to PF00005, ABC transporter, score 2e-44
553482002277	PS00017 ATP/GTP-binding site motif A (P-loop).
553482002278	PS00211 ABC transporters family signature.
553482002279	Bacterial ABC transporter protein EcsB; Region: EcsB; cl11542
553482002280	Bacterial ABC transporter protein EcsB; Region: EcsB; cl11542
553482002281	HMMPfam hit to PF05975, Bacterial ABC transporter protein EcsB, score 5.2e-146
553482002282	8 transmembrane helices predicted for SEQ0507 by TMHMM2.0 at aa 19-41, 56-78, 103-122, 126-148, 229-248, 253-275, 296-313 and 317-335
553482002283	Thiamine kinase and related kinases [Coenzyme transport and metabolism]; Region: ycfN; COG0510
553482002284	Phosphotransferase enzyme family; Region: APH; pfam01636
553482002285	substrate binding site [chemical binding]; other site
553482002286	HMMPfam hit to PF01636, Phosphotransferase enzyme family, score 3.1e-31
553482002287	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
553482002288	S-adenosylmethionine binding site [chemical binding]; other site
553482002289	HMMPfam hit to PF02390, methyltransferase, score 7.6e-57
553482002290	gene remnant. Similar to the C-terminal region of Streptococcus pyogenes serotype M1 phi5005.3 integrase UniProt:Q48X40 (EMBL:CP000017 (359 aa) fasta scores: E()=7.5e-08, 79.310% id in 29 aa
553482002291	gene remnant. Similar to an internal region of Streptococcus pyogenes serotype M6 transposase UniProt:Q5XBP0 (EMBL:CP000003 (74 aa) fasta scores: E()=3.8e-06, 73.077% id in 26 aa
553482002292	gene remnant. Similar to the C-terminal region of Lactobacillus plantarum integral membrane protein UniProt:Q88TN7 (EMBL:AL935260 (183 aa) fasta scores: E()=0.5, 42.222% id in 45 aa
553482002293	1 transmembrane helix predicted for SEQ0511 by TMHMM2.0 at aa 20-42
553482002294	gene remnant. CDS lacks appropriate translational start site
553482002295	HMMPfam hit to PF02576, Uncharacterised BCR, YhbC family COG0779, score 3.9e-53
553482002296	transcription elongation factor NusA; Provisional; Region: nusA; PRK12327
553482002297	NusA N-terminal domain; Region: NusA_N; pfam08529
553482002298	S1_NusA: N-utilizing substance A protein (NusA), S1-like RNA-binding domain. S1-like RNA-binding domains are found in a wide variety of RNA-associated proteins. NusA is a transcription elongation factor containing an N-terminal catalytic domain and three...; Region: S1_NusA; cd04455
553482002299	RNA binding site [nucleotide binding]; other site
553482002300	homodimer interface [polypeptide binding]; other site
553482002301	NusA-like KH domain; Region: KH_5; pfam13184
553482002302	NusA_K homology RNA-binding domain (KH). NusA is an essential multifunctional transcription elongation factor that is universally conserved among prokaryotes and archaea. NusA anti-termination function plays an important role in the expression of...; Region: NusA_KH; cd02134
553482002303	G-X-X-G motif; other site
553482002304	HMMPfam hit to PF08529, NusA N-terminal domain, score 1.2e-56
553482002305	HMMPfam hit to PF00575, S1 RNA binding domain, score 0.0001
553482002306	HMMPfam hit to PF00013, KH domain, score 0.029
553482002307	Ylxr homologs; group of conserved hypothetical bacterial proteins of unknown function; structure revealed putative RNA binding cleft; proteins are encoded by an operon that includes other proteins involved in transcription and/or translation; Region: YlxR; cd00279
553482002308	putative RNA binding cleft [nucleotide binding]; other site
553482002309	HMMPfam hit to PF04296, Protein of unknown function (DUF448), score 1.6e-34
553482002310	hypothetical protein; Provisional; Region: PRK07283
553482002311	HMMPfam hit to PF01248, Ribosomal protein L7Ae/L30e/S12e/Gadd4, score 2.1e-21
553482002312	Translation initiation factor IF-2, N-terminal region; Region: IF2_N; pfam04760
553482002313	translation initiation factor IF-2; Region: IF-2; TIGR00487
553482002314	Translation initiation factor IF-2, N-terminal region; Region: IF2_N; pfam04760
553482002315	Initiation Factor 2 (IF2)/ eukaryotic Initiation Factor 5B (eIF5B) family; Region: IF2_eIF5B; cd01887
553482002316	G1 box; other site
553482002317	putative GEF interaction site [polypeptide binding]; other site
553482002318	GTP/Mg2+ binding site [chemical binding]; other site
553482002319	Switch I region; other site
553482002320	G2 box; other site
553482002321	G3 box; other site
553482002322	Switch II region; other site
553482002323	G4 box; other site
553482002324	G5 box; other site
553482002325	This family represents the domain II of bacterial Initiation Factor 2 (IF2) and its eukaryotic mitochondrial homologue mtIF2. IF2, the largest initiation factor is an essential GTP binding protein. In E. coli three natural forms of IF2 exist in the cell; Region: IF2_mtIF2_II; cd03702
553482002326	Translation-initiation factor 2; Region: IF-2; pfam11987
553482002327	mtIF2_IVc: this family represents the C2 subdomain of domain IV of mitochondrial translation initiation factor 2 (mtIF2) which adopts a beta-barrel fold displaying a high degree of structural similarity with domain II of the translation elongation factor...; Region: mtIF2_IVc; cd03692
553482002328	HMMPfam hit to PF04760, Translation initiation factor IF-2, N-ter, score 2.5e-13
553482002329	HMMPfam hit to PF04760, Translation initiation factor IF-2, N-ter, score 3.6e-22
553482002330	PS00215 Mitochondrial energy transfer proteins signature.
553482002331	HMMPfam hit to PF00009, Elongation factor Tu GTP binding domain, score 9.9e-55
553482002332	HMMPfam hit to PF01926, GTPase of unknown function, score 3.8e-08
553482002333	PS00017 ATP/GTP-binding site motif A (P-loop).
553482002334	HMMPfam hit to PF03144, Elongation factor Tu domain, score 6.1e-11
553482002335	ribosome-binding factor A; Validated; Region: rbfA; PRK00521
553482002336	HMMPfam hit to PF02033, Ribosome-binding factor A, score 2.8e-27
553482002337	Protein of unknown function (DUF2424); Region: DUF2424; pfam10340
553482002338	alpha/beta hydrolase fold; Region: Abhydrolase_3; pfam07859
553482002339	HMMPfam hit to PF07859, alpha/beta hydrolase fold, score 5e-29
553482002340	copper transport repressor, CopY/TcrY family; Region: CopY_TcrY; TIGR02698
553482002341	Penicillinase repressor; Region: Pencillinase_R; pfam03965
553482002342	HMMPfam hit to PF03965, Penicillinase repressor, score 9.3e-45
553482002343	Cation transport ATPase [Inorganic ion transport and metabolism]; Region: ZntA; COG2217
553482002344	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
553482002345	metal-binding site [ion binding]
553482002346	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
553482002347	Soluble P-type ATPase [General function prediction only]; Region: COG4087
553482002348	HMMPfam hit to PF00403, Heavy-metal-associated domain, score 1.7e-15
553482002349	PS01047 Heavy-metal-associated domain.
553482002350	8 transmembrane helices predicted for SEQ0522 by TMHMM2.0 at aa 95-117, 127-144, 165-187, 192-214, 348-370, 380-402, 689-711 and 715-737
553482002351	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482002352	HMMPfam hit to PF00122, E1-E2 ATPase, score 1.2e-94
553482002353	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482002354	HMMPfam hit to PF00702, haloacid dehalogenase-like hydrolase, score 2.2e-35
553482002355	PS00154 E1-E2 ATPases phosphorylation site.
553482002356	Protein of unknown function (DUF3137); Region: DUF3137; pfam11335
553482002357	1 transmembrane helix predicted for SEQ0524 by TMHMM2.0 at aa 45-62
553482002358	LemA family; Region: LemA; cl00742
553482002359	HMMPfam hit to PF04011, LemA family, score 1.2e-08
553482002360	2 transmembrane helices predicted for SEQ0525 by TMHMM2.0 at aa 5-20 and 136-158
553482002361	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
553482002362	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
553482002363	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
553482002364	HMMPfam hit to PF00455, Bacterial regulatory proteins, deoR family, score 5.3e-67
553482002365	HMMPfam hit to PF08220, DeoR-like helix-turn-helix domain, score 9.1e-15
553482002366	HMMPfam hit to PF08279, HTH domain, score 0.0011
553482002367	galactose-6-phosphate isomerase subunit LacA; Provisional; Region: PRK12613
553482002368	HMMPfam hit to PF02502, Ribose/Galactose Isomerase, score 9.3e-45
553482002369	galactose-6-phosphate isomerase subunit LacB; Reviewed; Region: PRK08622
553482002370	HMMPfam hit to PF02502, Ribose/Galactose Isomerase, score 3.3e-42
553482002371	1-phosphofructokinase (FruK), minor 6-phosphofructokinase (pfkB) and related sugar kinases. FruK plays an important role in the predominant pathway for fructose utilisation.This group also contains tagatose-6-phophate kinase, an enzyme of the tagatose...; Region: FruK_PfkB_like; cd01164
553482002372	tagatose-6-phosphate kinase; Region: lacC; TIGR01231
553482002373	putative substrate binding site [chemical binding]; other site
553482002374	putative ATP binding site [chemical binding]; other site
553482002375	HMMPfam hit to PF00294, pfkB family carbohydrate kinase, score 2.1e-58
553482002376	PS00583 pfkB family of carbohydrate kinases signature 1.
553482002377	PS00584 pfkB family of carbohydrate kinases signature 2.
553482002378	gene remnant. The CDS appears to be truncated at the C-terminus. Similar to the N-terminal region of Streptococcus pyogenes serotype M18 tagatose 1,6-diphosphate aldolase 1 LacD1 UniProt:P63704 (EMBL:AE010082 (325 aa) fasta scores: E()=2.2e-20, 77.528% id in 89 aa
553482002379	gene remnant. The CDS appears to be truncated at the N-terminus. Similar to C-terminus of Staphylococcus aureus (strain MSSA476) 6-phospho-beta-galactosidase LacG UniProt:Q6G7C5 (EMBL:BX571857 (470 aa) fasta scores: E()=5.7e-41, 80.597% id in 134 aa
553482002380	HMMPfam hit to PF00232, Glycosyl hydrolase family, score 3.8e-08
553482002381	Domain of unknown function (DUF4300); Region: DUF4300; pfam14133
553482002382	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482002383	Predicted membrane protein [Function unknown]; Region: COG2860
553482002384	UPF0126 domain; Region: UPF0126; pfam03458
553482002385	UPF0126 domain; Region: UPF0126; pfam03458
553482002386	6 transmembrane helices predicted for SEQ0533 by TMHMM2.0 at aa 5-27, 32-54, 67-86, 90-112, 119-141 and 161-183
553482002387	HMMPfam hit to PF03458, UPF0126 domain, score 1.7e-27
553482002388	HMMPfam hit to PF03458, UPF0126 domain, score 6.5e-33
553482002389	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
553482002390	haloacid dehalogenase-like hydrolase; Region: Hydrolase_3; pfam08282
553482002391	active site
553482002392	motif I; other site
553482002393	motif II; other site
553482002394	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
553482002395	HMMPfam hit to PF05116, Sucrose-6F-phosphate phosphohydrolase, score 0.00061
553482002396	HMMPfam hit to PF00702, haloacid dehalogenase-like hydrolase, score 9.3e-08
553482002397	HMMPfam hit to PF08282, haloacid dehalogenase-like hydrolase, score 7.6e-78
553482002398	PS01229 Hypothetical cof family signature 2.
553482002399	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
553482002400	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
553482002401	HMMPfam hit to PF00440, Bacterial regulatory proteins, tetR family, score 3.3e-06
553482002402	Predicted helix-turn-helix motif with score 1203.000, SD 3.28 at aa 45-66, sequence ITISELVARAGVSRNAFYRNYS
553482002403	Uncharacterized protein conserved in bacteria [Function unknown]; Region: DegV; COG1307
553482002404	Uncharacterized protein, DegV family COG1307; Region: DegV; pfam02645
553482002405	HMMPfam hit to PF02645, Uncharacterized protein, DegV family COG1307, score 3.9e-67
553482002406	molecular chaperone DnaK; Provisional; Region: dnaK; PRK00290
553482002407	1 transmembrane helix predicted for SEQ0537 by TMHMM2.0 at aa 9-31
553482002408	Na+/phosphate symporter [Inorganic ion transport and metabolism]; Region: NptA; COG1283
553482002409	Na+/Pi-cotransporter; Region: Na_Pi_cotrans; pfam02690
553482002410	Na+/Pi-cotransporter; Region: Na_Pi_cotrans; pfam02690
553482002411	PhoU domain; Region: PhoU; pfam01895
553482002412	PhoU domain; Region: PhoU; pfam01895
553482002413	8 transmembrane helices predicted for SEQ0538 by TMHMM2.0 at aa 4-21, 41-60, 65-87, 99-121, 131-148, 173-195, 210-232 and 245-267
553482002414	HMMPfam hit to PF02690, Na+/Pi-cotransporter, score 1.1e-74
553482002415	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482002416	N-acetylglucosamine-6-phosphate deacetylase [Carbohydrate transport and metabolism]; Region: NagA; COG1820
553482002417	N-acetylglucosamine-6-phosphate deacetylase, NagA, catalyzes the hydrolysis of the N-acetyl group of N-acetyl-glucosamine-6-phosphate (GlcNAc-6-P) to glucosamine 6-phosphate and acetate. This is the first committed step in the biosynthetic pathway to...; Region: NagA; cd00854
553482002418	active site
553482002419	dimer interface [polypeptide binding]; other site
553482002420	HMMPfam hit to PF01979, Amidohydrolase family, score 9e-06
553482002421	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
553482002422	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
553482002423	active site
553482002424	catalytic tetrad [active]
553482002425	HMMPfam hit to PF00248, Aldo/keto reductase family, score 7.6e-109
553482002426	PS00798 Aldo/keto reductase family signature 1.
553482002427	PS00062 Aldo/keto reductase family signature 2.
553482002428	PS00063 Aldo/keto reductase family active site signature.
553482002429	gene remnant. Similar to an internal region of Lactobacillus salivarius subsp. salivarius (strain ucc118) ABC transporter, ATP-binding protein UniProt:Q1WV92 (EMBL:CP000233 (661 aa) fasta scores: E()=0.0006, 48.485% id in 66 aa
553482002430	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1755
553482002431	3 transmembrane helices predicted for SEQ0542 by TMHMM2.0 at aa 35-52, 59-81 and 122-144
553482002432	HMMPfam hit to PF04140, Isoprenylcysteine carboxyl methyltransferase, score 3.1e-47
553482002433	Class II Glycyl-tRNA synthetase (GlyRS) alpha subunit core catalytic domain. GlyRS functions as a homodimer in eukaryotes, archaea and some bacteria and as a heterotetramer in the remainder of prokaryotes and in arabidopsis. It is responsible for the...; Region: GlyRS_alpha_core; cd00733
553482002434	dimer interface [polypeptide binding]; other site
553482002435	motif 1; other site
553482002436	active site
553482002437	motif 2; other site
553482002438	motif 3; other site
553482002439	HMMPfam hit to PF02091, Glycyl-tRNA synthetase alpha subunit, score 2.8e-219
553482002440	PS00339 Aminoacyl-transfer RNA synthetases class-II signature 2.
553482002441	glycyl-tRNA synthetase subunit beta; Validated; Region: glyS; PRK01233
553482002442	DALR anticodon binding domain; Region: DALR_1; pfam05746
553482002443	HMMPfam hit to PF02092, Glycyl-tRNA synthetase beta subunit, score 5.2e-226
553482002444	HMMPfam hit to PF05746, DALR anticodon binding domain, score 0.00022
553482002445	hypothetical protein; Provisional; Region: PRK02539
553482002446	HMMPfam hit to PF05979, Bacterial protein of unknown function (DUF89, score 2.9e-42
553482002447	This family is the oxydase domain of NRPS (non-ribosomal peptide synthetase) and other proteins that modify polypeptides by cyclizing a thioester to form a ring. These include epoB, part of the epothilone biosynthesis pathway; tubD, part of the tubulysin...; Region: mcbC-like_oxidoreductase; cd02142
553482002448	putative FMN binding site [chemical binding]; other site
553482002449	NADPH bind site [chemical binding]; other site
553482002450	thiazole/oxazole-forming peptide maturase, SagC family component; Region: cyclo_dehy_ocin; TIGR03603
553482002451	thiazole/oxazole-forming peptide maturase, SagD family component; Region: TOMM_cyclo_SagD; TIGR03604
553482002452	YcaO-like family; Region: YcaO; pfam02624
553482002453	HMMPfam hit to PF02624, YcaO-like family, score 1.2e-07
553482002454	CAAX protease self-immunity; Region: Abi; pfam02517
553482002455	5 transmembrane helices predicted for SEQ0550 by TMHMM2.0 at aa 7-29, 39-61, 74-96, 147-169 and 182-204
553482002456	HMMPfam hit to PF02517, CAAX amino terminal protease family, score 0.00021
553482002457	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482002458	6 transmembrane helices predicted for SEQ0551 by TMHMM2.0 at aa 4-21, 42-64, 84-106, 134-156, 160-182 and 189-211
553482002459	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
553482002460	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
553482002461	Walker A/P-loop; other site
553482002462	ATP binding site [chemical binding]; other site
553482002463	Q-loop/lid; other site
553482002464	ABC transporter signature motif; other site
553482002465	Walker B; other site
553482002466	D-loop; other site
553482002467	H-loop/switch region; other site
553482002468	HMMPfam hit to PF00005, ABC transporter, score 1.8e-66
553482002469	PS00017 ATP/GTP-binding site motif A (P-loop).
553482002470	PS00211 ABC transporters family signature.
553482002471	ABC-2 family transporter protein; Region: ABC2_membrane_3; pfam12698
553482002472	ABC-2 type transporter; Region: ABC2_membrane; pfam01061
553482002473	6 transmembrane helices predicted for SEQ0553 by TMHMM2.0 at aa 20-39, 182-204, 225-247, 262-284, 289-311 and 345-367
553482002474	HMMPfam hit to PF01061, ABC-2 type transporter, score 8.8e-07
553482002475	ABC-2 family transporter protein; Region: ABC2_membrane_3; pfam12698
553482002476	ABC-2 type transporter; Region: ABC2_membrane; pfam01061
553482002477	6 transmembrane helices predicted for SEQ0554 by TMHMM2.0 at aa 20-42, 182-204, 225-247, 257-279, 292-314 and 345-367
553482002478	HMMPfam hit to PF01061, ABC-2 type transporter, score 1.2e-13
553482002479	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482002480	Fibronectin-binding protein signal sequence; Region: Fb_signal; pfam08341
553482002481	TQXA domain; Region: TQXA_dom; TIGR03934
553482002482	2 transmembrane helices predicted for SEQ0555 by TMHMM2.0 at aa 9-31 and 385-404
553482002483	HMMPfam hit to PF08341, Fibronectin-binding protein signal sequence, score 5.6e-09
553482002484	gene remnant. CDS lacks an N-terminal signal sequence, therefore it will not be processed correctly. Similar to the C-terminal region of Streptococcus equi subsp. equi collagen-like protein G SclG UniProt:Q1I0L6 (EMBL:DQ158083 (397 aa) fasta scores: E()=4.6e-25, 36.929% id in 241 aa
553482002485	1 transmembrane helix predicted for SEQ0556 by TMHMM2.0 at aa 395-414
553482002486	HMMPfam hit to PF01391, Collagen triple helix repeat (20 copies), score 1.6e-11
553482002487	HMMPfam hit to PF01391, Collagen triple helix repeat (20 copies), score 1.3e-12
553482002488	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482002489	CutC family; Region: CutC; pfam03932
553482002490	HMMPfam hit to PF03932, CutC family, score 2.5e-116
553482002491	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
553482002492	Coenzyme A binding pocket [chemical binding]; other site
553482002493	HMMPfam hit to PF00583, Acetyltransferase (GNAT) family, score 1.4e-05
553482002494	Methylated DNA-protein cysteine methyltransferase [DNA replication, recombination, and repair]; Region: Ada; COG0350
553482002495	The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445
553482002496	DNA binding site [nucleotide binding]
553482002497	active site
553482002498	HMMPfam hit to PF01035, 6-O-methylguanine DNA methyltransferase, score 2e-39
553482002499	PS00374 Methylated-DNA--protein-cysteine methyltransferase active site.
553482002500	Arsenate Reductase (ArsC) family, unknown subfamily; uncharacterized proteins containing a CXXC motif with similarity to thioredoxin (TRX)-fold arsenic reductases, ArsC. Proteins containing a redox active CXXC motif like TRX and glutaredoxin (GRX)...; Region: ArsC_like; cd03036
553482002501	ArsC family; Region: ArsC; pfam03960
553482002502	putative ArsC-like catalytic residues; other site
553482002503	putative TRX-like catalytic residues [active]
553482002504	HMMPfam hit to PF03960, ArsC family, score 1.8e-29
553482002505	Human Ape1-like subfamily of the ExoIII family purinic/apyrimidinic (AP) endonucleases; Region: Ape1-like_AP-endo; cd09087
553482002506	active site
553482002507	putative catalytic site [active]
553482002508	DNA binding site [nucleotide binding]
553482002509	putative phosphate binding site [ion binding]; other site
553482002510	metal binding site A [ion binding]; metal-binding site
553482002511	AP binding site [nucleotide binding]; other site
553482002512	metal binding site B [ion binding]; metal-binding site
553482002513	PS00728 AP endonucleases family 1 signature 3.
553482002514	PS00726 AP endonucleases family 1 signature 1.
553482002515	Gram-positive signal peptide, YSIRK family; Region: YSIRK_signal; TIGR01168
553482002516	Peptidase S8 family domain in Streptococcal C5a peptidases; Region: Peptidases_S8_C5a_Peptidase; cd07475
553482002517	putative active site [active]
553482002518	catalytic triad [active]
553482002519	PA_C5a_like: Protease-associated domain containing proteins like Streptococcus pyogenes C5a peptidase. This group contains various PA domain-containing proteins similar to S. pyogenes C5a, including, i) Vpr, a minor extracellular serine protease from...; Region: PA_C5a_like; cd02133
553482002520	putative integrin binding motif; other site
553482002521	PA/protease domain interface [polypeptide binding]; other site
553482002522	Peptidase S8 family domain in Streptococcal C5a peptidases; Region: Peptidases_S8_C5a_Peptidase; cd07475
553482002523	Fn3-like domain (DUF1034); Region: DUF1034; pfam06280
553482002524	HMMPfam hit to PF04650, YSIRK type signal peptide, score 3.6e-07
553482002525	1 transmembrane helix predicted for SEQ0563 by TMHMM2.0 at aa 12-34
553482002526	HMMPfam hit to PF00082, Subtilase family, score 6.3e-41
553482002527	PS00136 Serine proteases, subtilase family, aspartic acid active site.
553482002528	PS00137 Serine proteases, subtilase family, histidine active site.
553482002529	HMMPfam hit to PF02225, PA domain, score 4.2e-13
553482002530	PS00138 Serine proteases, subtilase family, serine active site.
553482002531	HMMPfam hit to PF06280, Domain of Unknown Function (DUF1034), score 6.8e-46
553482002532	HMMPfam hit to PF00746, Gram positive anchor, score 8.2e-05
553482002533	PS00343 Gram-positive cocci surface proteins 'anchoring' hexapeptide.
553482002534	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482002535	3 transmembrane helices predicted for SEQ0564 by TMHMM2.0 at aa 5-27, 37-59 and 87-109
553482002536	CDS contains a frameshift around codon 182. Similar to Streptococcus equi M-like protein precursor emmszw60 UniProt:Q54071 (EMBL:U04620 (376 aa) fasta scores: E()=3.4e-14, 34.615% id in 390 aa
553482002537	1 transmembrane helix predicted for SEQ0566 by TMHMM2.0 at aa 13-35
553482002538	HMMPfam hit to PF00746, Gram positive anchor, score 1.6e-11
553482002539	PS00343 Gram-positive cocci surface proteins 'anchoring' hexapeptide.
553482002540	1 transmembrane helix predicted for SEQ0567 by TMHMM2.0 at aa 112-134
553482002541	Predicted membrane protein [Function unknown]; Region: COG3619
553482002542	4 transmembrane helices predicted for SEQ0568 by TMHMM2.0 at aa 12-34, 65-87, 94-116 and 178-200
553482002543	HMMPfam hit to PF06912, Protein of unknown function (DUF1275), score 9e-76
553482002544	methionyl-tRNA synthetase; Reviewed; Region: PRK12267
553482002545	catalytic core domain of methioninyl-tRNA synthetases; Region: MetRS_core; cd00814
553482002546	active site
553482002547	HIGH motif; other site
553482002548	KMSKS motif; other site
553482002549	Anticodon-binding domain of methionyl tRNA synthetases; Region: Anticodon_Ia_Met; cd07957
553482002550	tRNA binding surface [nucleotide binding]; other site
553482002551	anticodon binding site; other site
553482002552	tRNA-binding-domain-containing Escherichia coli methionyl-tRNA synthetase (EcMetRS)-like proteins.  This family includes EcMetRS and Aquifex aeolicus Trbp111 (AaTrbp111). This domain has general tRNA binding properties.  MetRS aminoacylates methionine...; Region: tRNA_bind_EcMetRS_like; cd02800
553482002553	dimer interface [polypeptide binding]; other site
553482002554	putative tRNA-binding site [nucleotide binding]; other site
553482002555	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482002556	HMMPfam hit to PF01588, tRNA binding domain, score 2.8e-30
553482002557	ribonucleotide-diphosphate reductase subunit beta; Provisional; Region: nrdF2; PRK13966
553482002558	Ribonucleotide Reductase, R2/beta subunit, ferritin-like diiron-binding domain; Region: RNRR2; cd01049
553482002559	dimer interface [polypeptide binding]; other site
553482002560	putative radical transfer pathway; other site
553482002561	diiron center [ion binding]; other site
553482002562	tyrosyl radical; other site
553482002563	HMMPfam hit to PF00268, Ribonucleotide reductase, small chain, score 3e-38
553482002564	1 transmembrane helix predicted for SEQ0570 by TMHMM2.0 at aa 170-192
553482002565	ribonucleotide reductase stimulatory protein; Reviewed; Region: nrdI; PRK03600
553482002566	HMMPfam hit to PF07972, NrdI Flavodoxin like, score 3e-73
553482002567	ribonucleotide-diphosphate reductase subunit alpha; Validated; Region: PRK07187
553482002568	Ribonucleotide reductase N-terminal; Region: RNR_N; pfam08343
553482002569	Class I ribonucleotide reductase; Region: RNR_I; cd01679
553482002570	active site
553482002571	dimer interface [polypeptide binding]; other site
553482002572	catalytic residues [active]
553482002573	effector binding site; other site
553482002574	R2 peptide binding site; other site
553482002575	HMMPfam hit to PF08343, Ribonucleotide reductase N-terminal, score 5.4e-35
553482002576	HMMPfam hit to PF00317, Ribonucleotide reductase, all-alpha d, score 2.5e-25
553482002577	HMMPfam hit to PF02867, Ribonucleotide reductase, barrel doma, score 2e-164
553482002578	PS00089 Ribonucleotide reductase large subunit signature.
553482002579	gene remnant generated by the insertion of the an IS element and subsequent recombination events
553482002580	putative transposase OrfB; Reviewed; Region: PHA02517
553482002581	HTH-like domain; Region: HTH_21; pfam13276
553482002582	Integrase core domain; Region: rve; pfam00665
553482002583	Integrase core domain; Region: rve_2; pfam13333
553482002584	HMMPfam hit to PF00665, Integrase core domain, score 8.8e-38
553482002585	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
553482002586	Helix-turn-helix domain; Region: HTH_28; pfam13518
553482002587	HMMPfam hit to PF01527, Transposase, score 0.00062
553482002588	HMMPfam hit to PF02178, no description, score 0.21
553482002589	Predicted helix-turn-helix motif with score 1140.000, SD 3.07 at aa 19-40, sequence KSIKCLSEKFSIAESDLKYMIR
553482002590	CDS is truncated by the insertion of the upstream IS element
553482002591	1 transmembrane helix predicted for SEQ0576 by TMHMM2.0 at aa 94-116
553482002592	CDS contains a frameshift after codon 13. Frameshift occurs at a poly T hexamer
553482002593	WXG100 protein secretion system (Wss), protein YukC; Region: YukC; cl01868
553482002594	type VII secretion protein EssB; Region: T7_EssB; TIGR03926
553482002595	1 transmembrane helix predicted for SEQ0579 by TMHMM2.0 at aa 210-232
553482002596	type VII secretion protein EssC, C-terminal domain; Region: T7_EssCb_Firm; TIGR03928
553482002597	FtsK/SpoIIIE family; Region: FtsK_SpoIIIE; pfam01580
553482002598	FtsK/SpoIIIE family; Region: FtsK_SpoIIIE; pfam01580
553482002599	1 transmembrane helix predicted for SEQ0580 by TMHMM2.0 at aa 213-235
553482002600	HMMPfam hit to PF01580, FtsK/SpoIIIE family, score 3.4e-38
553482002601	PS00017 ATP/GTP-binding site motif A (P-loop).
553482002602	HMMPfam hit to PF01580, FtsK/SpoIIIE family, score 2.4e-24
553482002603	Domain of unknown function (DUF4176); Region: DUF4176; pfam13780
553482002604	Protein of unknown function (DUF3130; Region: DUF3130; cl12867
553482002608	HMMPfam hit to PF01610, Transposase, score 1.3e-06
553482002609	Predicted helix-turn-helix motif with score 1376.000, SD 3.87 at aa 130-151, sequence EAFTHIAAKLAISTSTVYHKLK
553482002610	Cytochrome c biogenesis protein [Posttranslational modification, protein turnover, chaperones]; Region: CcdA; COG0785
553482002611	Cytochrome C biogenesis protein transmembrane region; Region: DsbD; cl15788
553482002612	6 transmembrane helices predicted for SEQ0587 by TMHMM2.0 at aa 10-32, 51-73, 88-110, 130-152, 172-194 and 207-226
553482002613	HMMPfam hit to PF02683, Cytochrome C biogenesis protein transmembran, score 1.8e-56
553482002614	PS00086 Cytochrome P450 cysteine heme-iron ligand signature.
553482002615	TlpA-like family; composed of  TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a...; Region: TlpA_like_family; cd02966
553482002616	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
553482002617	catalytic residues [active]
553482002618	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482002619	HMMPfam hit to PF08534, Redoxin, score 1.3e-26
553482002620	Peptide methionine sulfoxide reductase [Posttranslational modification, protein turnover, chaperones]; Region: MsrA; COG0225
553482002621	Conserved domain frequently associated with peptide methionine sulfoxide reductase [Posttranslational modification, protein turnover, chaperones]; Region: COG0229
553482002622	SelR domain; Region: SelR; pfam01641
553482002623	1 transmembrane helix predicted for SEQ0589 by TMHMM2.0 at aa 7-29
553482002624	HMMPfam hit to PF01625, Peptide methionine sulfoxide reductase, score 1.4e-83
553482002625	HMMPfam hit to PF01641, SelR domain, score 2.7e-81
553482002626	Response regulator receiver domain; Region: Response_reg; pfam00072
553482002627	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
553482002628	active site
553482002629	phosphorylation site [posttranslational modification]
553482002630	intermolecular recognition site; other site
553482002631	dimerization interface [polypeptide binding]; other site
553482002632	Helix-turn-helix domain; Region: HTH_18; pfam12833
553482002633	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
553482002634	HMMPfam hit to PF00072, Response regulator receiver domain, score 6.8e-36
553482002635	HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix pr, score 8.7e-06
553482002636	Predicted helix-turn-helix motif with score 1473.000, SD 4.20 at aa 159-180, sequence LTLKSLSSQLGFSPNYLSVLIK
553482002637	PS00041 Bacterial regulatory proteins, araC family signature.
553482002638	HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix pr, score 2e-12
553482002639	Predicted signal transduction protein with a C-terminal ATPase domain [Signal transduction mechanisms]; Region: COG2972
553482002640	Cache domain; Region: Cache_1; pfam02743
553482002641	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
553482002642	dimerization interface [polypeptide binding]; other site
553482002643	Histidine kinase; Region: His_kinase; pfam06580
553482002644	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
553482002645	ATP binding site [chemical binding]; other site
553482002646	Mg2+ binding site [ion binding]; other site
553482002647	G-X-G motif; other site
553482002648	2 transmembrane helices predicted for SEQ0591 by TMHMM2.0 at aa 10-29 and 281-303
553482002649	HMMPfam hit to PF02743, Cache domain, score 1.6e-17
553482002650	HMMPfam hit to PF00672, HAMP domain, score 3.2e-13
553482002651	HMMPfam hit to PF06580, Histidine kinase, score 1e-42
553482002652	HMMPfam hit to PF02518, Histidine kinase-, DNA gyrase B-, and HSP9, score 6e-11
553482002653	Uncharacterized protein conserved in bacteria [Function unknown]; Region: MmcQ; COG2315
553482002654	HMMPfam hit to PF04237, Protein of unknown function (DUF419), score 1.5e-37
553482002655	PS00213 Lipocalin signature.
553482002656	Solo B3/4 domain (OB-fold DNA/RNA-binding) of Phe-aaRS-beta [General function prediction only]; Region: COG3382
553482002657	B3/4 domain; Region: B3_4; pfam03483
553482002658	HMMPfam hit to PF03483, B3/4 domain, score 2.6e-26
553482002659	This CD includes bacterial (Agrobacterium tumefaciens and Caulobacter crescentus ProX, and Clostridium sticklandii PrdX) and eukaryotic (Plasmodium falciparum N-terminal ProRS editing domain) sequences. The C. sticklandii PrdX protein, a homolog of the...; Region: PrdX_deacylase; cd04335
553482002660	putative deacylase active site [active]
553482002661	HMMPfam hit to PF04073, YbaK / prolyl-tRNA synthetases associated do, score 8e-08
553482002662	Arginine repressor [Transcription]; Region: ArgR; COG1438
553482002663	Arginine repressor, DNA binding domain; Region: Arg_repressor; pfam01316
553482002664	Arginine repressor, C-terminal domain; Region: Arg_repressor_C; pfam02863
553482002665	HMMPfam hit to PF02863, Arginine repressor, C-terminal domain, score 2.7e-25
553482002666	HMMPfam hit to PF01316, Arginine repressor, DNA binding domai, score 3.8e-24
553482002667	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
553482002668	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
553482002669	ligand binding site [chemical binding]; other site
553482002670	flexible hinge region; other site
553482002671	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cd00092
553482002672	putative switch regulator; other site
553482002673	non-specific DNA interactions [nucleotide binding]; other site
553482002674	DNA binding site [nucleotide binding]
553482002675	sequence specific DNA binding site [nucleotide binding]; other site
553482002676	putative cAMP binding site [chemical binding]; other site
553482002677	HMMPfam hit to PF00027, Cyclic nucleotide-binding domain, score 2.1e-17
553482002678	HMMPfam hit to PF00325, Bacterial regulatory proteins, crp famil, score 3.4e-07
553482002679	Predicted helix-turn-helix motif with score 2209.000, SD 6.71 at aa 177-198, sequence LTTTDIAQMSGTTRETVSHVFR
553482002680	arginine deiminase; Provisional; Region: PRK01388
553482002681	HMMPfam hit to PF02274, Amidinotransferase, score 3.2e-204
553482002682	Autoinducer synthetase; Region: Autoind_synth; cl17404
553482002683	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
553482002684	Coenzyme A binding pocket [chemical binding]; other site
553482002685	HMMPfam hit to PF00583, Acetyltransferase (GNAT) family, score 2.4e-14
553482002686	ornithine carbamoyltransferase; Validated; Region: PRK02102
553482002687	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
553482002688	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
553482002689	HMMPfam hit to PF02729, Aspartate/ornithine carbamoyltransferase, ca, score 8.3e-70
553482002690	PS00097 Aspartate and ornithine carbamoyltransferases signature.
553482002691	HMMPfam hit to PF00185, Aspartate/ornithine carbamoyltransferase, As, score 2.2e-79
553482002692	Predicted membrane protein [Function unknown]; Region: COG1288
553482002693	C4-dicarboxylate anaerobic carrier; Region: DcuC; pfam03606
553482002694	HMMPfam hit to PF03606, C4-dicarboxylate anaerobic carrier, score 2.8e-242
553482002695	13 transmembrane helices predicted for SEQ0600 by TMHMM2.0 at aa 13-35, 79-98, 119-138, 148-170, 175-197, 201-223, 261-279, 312-334, 341-363, 378-400, 407-429, 444-466 and 479-496
553482002696	hypothetical protein; Provisional; Region: PRK07205
553482002697	M20 Peptidase Xaa-His dipeptidase (PepV) degrades hydrophobic dipeptides; Region: M20_PepV; cd03888
553482002698	active site
553482002699	metal binding site [ion binding]; metal-binding site
553482002700	HMMPfam hit to PF01546, Peptidase family M20/M25/M40, score 7e-24
553482002701	Predicted helix-turn-helix motif with score 1077.000, SD 2.86 at aa 422-443, sequence IVLADAYRAMDIYAEAIYRLTR
553482002702	carbamate kinase; Reviewed; Region: PRK12686
553482002703	AAK_CK: Carbamate kinase (CK) catalyzes both the ATP-phosphorylation of carbamate and carbamoyl phosphate (CP) utilization with the production of ATP from ADP and CP. Both CK (this CD) and nonhomologous CP synthetase synthesize carbamoyl phosphate, an...; Region: AAK_CK; cd04235
553482002704	putative substrate binding site [chemical binding]; other site
553482002705	nucleotide binding site [chemical binding]; other site
553482002706	nucleotide binding site [chemical binding]; other site
553482002707	homodimer interface [polypeptide binding]; other site
553482002708	HMMPfam hit to PF00696, Amino acid kinase family, score 3.7e-97
553482002709	Asparagine synthetase (aspartate-ammonia ligase) (AsnA) catalyses the conversion of L-aspartate to L-asparagine in the presence of ATP and ammonia.  AsnA is a homodimeric enzyme which is structurally similiar to the catalytic core domain of class II...; Region: AsnA; cd00645
553482002710	dimer interface [polypeptide binding]; other site
553482002711	active site
553482002712	HMMPfam hit to PF03590, Aspartate-ammonia ligase, score 6.1e-179
553482002713	Conserved hypothetical protein 95; Region: Cons_hypoth95; pfam03602
553482002714	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
553482002715	S-adenosylmethionine binding site [chemical binding]; other site
553482002716	HMMPfam hit to PF03602, Conserved hypothetical protein, score 5.3e-91
553482002717	PS00092 N-6 Adenine-specific DNA methylases signature.
553482002718	phosphopantetheine adenylyltransferase; Provisional; Region: coaD; PRK00168
553482002719	Phosphopantetheine adenylyltransferase; Region: PPAT; cd02163
553482002720	active site
553482002721	(T/H)XGH motif; other site
553482002722	HMMPfam hit to PF01467, Cytidylyltransferase, score 5.3e-25
553482002723	HMMPfam hit to PF08218, Citrate lyase ligase C-terminal domain, score 0.0018
553482002724	Predicted secreted protein containing a PDZ domain [Signal transduction mechanisms]; Region: SdrC; COG3480
553482002725	PDZ domain, also called DHR (Dlg homologous region) or GLGF (after a conserved sequence motif). Many PDZ domains bind C-terminal polypeptides, though binding to internal (non-C-terminal) polypeptides and even to lipids has been demonstrated; Region: PDZ; cl00117
553482002726	protein binding site [polypeptide binding]; other site
553482002727	1 transmembrane helix predicted for SEQ0606 by TMHMM2.0 at aa 9-31
553482002728	Protein of unknown function (DUF1027); Region: DUF1027; cl09961
553482002729	HMMPfam hit to PF06265, Protein of unknown function (DUF1027), score 9.8e-57
553482002730	ribosomal RNA large subunit methyltransferase N; Provisional; Region: PRK14455
553482002731	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
553482002732	FeS/SAM binding site; other site
553482002733	6 transmembrane helices predicted for SEQ0610 by TMHMM2.0 at aa 4-21, 71-93, 108-130, 132-154, 169-186 and 193-212
553482002734	HMMPfam hit to PF01478, Type IV leader peptidase family, score 7.6e-11
553482002735	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482002736	DNA-binding ferritin-like protein (oxidative damage protectant) [Inorganic ion transport and metabolism]; Region: Dps; COG0783
553482002737	DPS protein, ferritin-like diiron-binding domain; Region: DPS; cd01043
553482002738	dimerization interface [polypeptide binding]; other site
553482002739	DPS ferroxidase diiron center [ion binding]; other site
553482002740	ion pore; other site
553482002741	HMMPfam hit to PF00210, Ferritin-like domain, score 1.5e-33
553482002742	PS00818 Dps protein family signature 1.
553482002743	Bacterial protein of unknown function (DUF910); Region: DUF910; pfam06014
553482002744	HMMPfam hit to PF06014, Bacterial protein of unknown function (DUF91, score 2e-35
553482002745	ROK family protein (putative glucokinase); Region: ROK_glcA_fam; TIGR00744
553482002746	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
553482002747	nucleotide binding site [chemical binding]; other site
553482002748	HMMPfam hit to PF00480, ROK family, score 3e-42
553482002749	PS01125 ROK family signature.
553482002750	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482002751	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
553482002752	active site residue [active]
553482002753	1 transmembrane helix predicted for SEQ0614 by TMHMM2.0 at aa 4-26
553482002754	HMMPfam hit to PF00581, Rhodanese-like domain, score 8.3e-07
553482002755	Predicted membrane GTPase involved in stress response [Signal transduction mechanisms]; Region: TypA; COG1217
553482002756	Tyrosine phosphorylated protein A (TypA)/BipA family belongs to ribosome-binding GTPases; Region: TypA_BipA; cd01891
553482002757	G1 box; other site
553482002758	putative GEF interaction site [polypeptide binding]; other site
553482002759	GTP/Mg2+ binding site [chemical binding]; other site
553482002760	Switch I region; other site
553482002761	G2 box; other site
553482002762	G3 box; other site
553482002763	Switch II region; other site
553482002764	G4 box; other site
553482002765	G5 box; other site
553482002766	BipA_TypA_II: domain II of BipA (also called TypA) having homology to domain II of the elongation factors (EFs) EF-G and EF-Tu.  BipA is a highly conserved protein with global regulatory properties in Escherichia coli. BipA is phosphorylated on a...; Region: BipA_TypA_II; cd03691
553482002767	BipA_TypA_C: a C-terminal portion of BipA or TypA having homology to the C terminal domains of the elongation factors EF-G and EF-2. A member of the ribosome binding GTPase superfamily, BipA is widely distributed in bacteria and plants.  BipA is a highly...; Region: BipA_TypA_C; cd03710
553482002768	HMMPfam hit to PF00009, Elongation factor Tu GTP binding domain, score 1.8e-68
553482002769	PS00017 ATP/GTP-binding site motif A (P-loop).
553482002770	PS00301 GTP-binding elongation factors signature.
553482002771	HMMPfam hit to PF03144, Elongation factor Tu domain, score 3.8e-17
553482002772	HMMPfam hit to PF00679, Elongation factor G C-terminus, score 2.1e-27
553482002773	Protein of unknown function (DUF3165); Region: DUF3165; pfam11364
553482002774	3 transmembrane helices predicted for SEQ0616 by TMHMM2.0 at aa 2-19, 25-47 and 56-73
553482002775	UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase; Provisional; Region: murD; PRK02472
553482002776	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
553482002777	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
553482002778	HMMPfam hit to PF08245, Mur ligase middle domain, score 1.7e-64
553482002779	HMMPfam hit to PF02875, Mur ligase family, glutamate ligase doma, score 5.3e-17
553482002780	undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase; Provisional; Region: murG; PRK00726
553482002781	MurG is an N-acetylglucosaminyltransferase, the last enzyme involved in the intracellular phase of peptidoglycan biosynthesis. It transfers N-acetyl-D-glucosamine (GlcNAc) from UDP-GlcNAc to the C4 hydroxyl of a lipid-linked N-acetylmuramoyl pentapeptide...; Region: GT1_MurG; cd03785
553482002782	active site
553482002783	homodimer interface [polypeptide binding]; other site
553482002784	HMMPfam hit to PF03033, Glycosyltransferase family, score 7.2e-38
553482002785	HMMPfam hit to PF04101, Glycosyltransferase family, score 1.5e-24
553482002786	POTRA domain, FtsQ-type; Region: POTRA_1; pfam08478
553482002787	Cell division protein FtsQ; Region: FtsQ; pfam03799
553482002788	1 transmembrane helix predicted for SEQ0619 by TMHMM2.0 at aa 115-137
553482002789	HMMPfam hit to PF08478, POTRA domain, FtsQ-type, score 9.8e-16
553482002790	HMMPfam hit to PF03799, Cell division protein FtsQ, score 2.6e-28
553482002791	Cell division ATPase FtsA [Cell division and chromosome partitioning]; Region: ftsA; COG0849
553482002792	Cell division protein FtsA; Region: FtsA; smart00842
553482002793	Cell division protein FtsA; Region: FtsA; pfam14450
553482002794	Domain of unknown function (DUF3484); Region: DUF3484; pfam11983
553482002795	HMMPfam hit to PF02491, Cell division protein FtsA, score 7.2e-70
553482002796	HMMPfam hit to PF02491, Cell division protein FtsA, score 4.8e-47
553482002797	cell division protein FtsZ; Validated; Region: PRK09330
553482002798	FtsZ is a GTPase that is similar to the eukaryotic tubulins and is essential for cell division in prokaryotes.  FtsZ is capable of polymerizing in a GTP-driven process into structures similar to those formed by tubulin. FtsZ forms a ring-shaped septum at...; Region: FtsZ_type1; cd02201
553482002799	nucleotide binding site [chemical binding]; other site
553482002800	SulA interaction site; other site
553482002801	HMMPfam hit to PF00091, Tubulin/FtsZ family, GTPase domain, score 4.7e-96
553482002802	PS01134 FtsZ protein signature 1.
553482002803	HMMPfam hit to PF03953, Tubulin/FtsZ family, C-terminal domain, score 7.7e-24
553482002804	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes, YBL036c-like proteins; Region: PLPDE_III_YBL036c_like; cd00635
553482002805	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
553482002806	catalytic residue [active]
553482002807	HMMPfam hit to PF01168, Alanine racemase, N-terminal domain, score 1.1e-07
553482002808	PS01211 Uncharacterized protein family UPF0001 signature.
553482002809	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1799
553482002810	HMMPfam hit to PF04472, Protein of unknown function (DUF552), score 2.5e-45
553482002811	YGGT family; Region: YGGT; pfam02325
553482002812	HMMPfam hit to PF02325, YGGT family, score 1.4e-26
553482002813	2 transmembrane helices predicted for SEQ0624 by TMHMM2.0 at aa 7-29 and 59-81
553482002814	Uncharacterized conserved protein, contains S4-like domain [Function unknown]; Region: COG2302
553482002815	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
553482002816	RNA binding surface [nucleotide binding]; other site
553482002817	HMMPfam hit to PF01479, S4 domain, score 1.4e-10
553482002818	DivIVA protein; Region: DivIVA; pfam05103
553482002819	DivIVA domain; Region: DivI1A_domain; TIGR03544
553482002820	HMMPfam hit to PF05103, DivIVA protein, score 8.8e-112
553482002821	isoleucyl-tRNA synthetase; Provisional; Region: ileS; PRK13804
553482002822	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
553482002823	active site
553482002824	HIGH motif; other site
553482002825	nucleotide binding site [chemical binding]; other site
553482002826	catalytic core domain of isoleucyl-tRNA synthetases; Region: IleRS_core; cd00818
553482002827	active site
553482002828	KMSKS motif; other site
553482002829	Anticodon-binding domain of bacterial and eukaryotic mitochondrial isoleucyl tRNA synthetases; Region: Anticodon_Ia_Ile_BEm; cd07960
553482002830	tRNA binding surface [nucleotide binding]; other site
553482002831	anticodon binding site; other site
553482002832	HMMPfam hit to PF00133, tRNA synthetases class I (I, L, M and V), score 8.8e-274
553482002833	PS00178 Aminoacyl-transfer RNA synthetases class-I signature.
553482002834	HMMPfam hit to PF08264, Anticodon-binding domain, score 1.9e-54
553482002835	HMMPfam hit to PF06827, Zinc finger found in FPG and IleRS, score 8.9e-05
553482002836	Domain of unknown function (DUF1827); Region: DUF1827; pfam08860
553482002837	Contains a crystal structure of the Nudix hydrolase from Enterococcus faecalis, which has an unknown function. In general, members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes...; Region: Nudix_Hydrolase_25; cd04684
553482002838	nudix motif; other site
553482002839	HMMPfam hit to PF00293, NUDIX domain, score 7.9e-12
553482002840	PS00893 mutT domain signature.
553482002841	ATP-binding subunits of Clp protease and DnaK/DnaJ chaperones [Posttranslational modification, protein turnover, chaperones]; Region: clpA; COG0542
553482002842	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
553482002843	Walker A motif; other site
553482002844	ATP binding site [chemical binding]; other site
553482002845	Walker B motif; other site
553482002846	arginine finger; other site
553482002847	UvrB/uvrC motif; Region: UVR; pfam02151
553482002848	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
553482002849	Walker A motif; other site
553482002850	ATP binding site [chemical binding]; other site
553482002851	Walker B motif; other site
553482002852	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431
553482002853	HMMPfam hit to PF07728, ATPase family associated with various cellul, score 0.00022
553482002854	HMMPfam hit to PF07724, ATPase family associated with various cellul, score 1.7e-99
553482002855	PS00871 Chaperonins clpA/B signature 2.
553482002856	PS00017 ATP/GTP-binding site motif A (P-loop).
553482002857	HMMPfam hit to PF02151, UvrB/uvrC motif, score 0.00014
553482002858	HMMPfam hit to PF00004, ATPase family associated with various cellul, score 3.3e-10
553482002859	HMMPfam hit to PF07728, ATPase family associated with various cellul, score 0.00072
553482002860	PS00870 Chaperonins clpA/B signature 1.
553482002861	PS00017 ATP/GTP-binding site motif A (P-loop).
553482002862	Protein of unknown function (DUF1797); Region: DUF1797; cl11550
553482002863	Gram positive anchor; Region: Gram_pos_anchor; pfam00746
553482002864	HMMPfam hit to PF00746, Gram positive anchor, score 1.7e-10
553482002865	PS00343 Gram-positive cocci surface proteins 'anchoring' hexapeptide.
553482002866	HMMPfam hit to PF01391, Collagen triple helix repeat (20 copi, score 3.6e-16
553482002867	HMMPfam hit to PF01391, Collagen triple helix repeat (20 copi, score 4.5e-10
553482002868	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
553482002869	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
553482002870	dimer interface [polypeptide binding]; other site
553482002871	conserved gate region; other site
553482002872	putative PBP binding loops; other site
553482002873	ABC-ATPase subunit interface; other site
553482002874	HMMPfam hit to PF00528, Binding-protein-dependent transport syst, score 6.7e-26
553482002875	3 transmembrane helices predicted for SEQ0634 by TMHMM2.0 at aa 15-37, 50-72 and 196-218
553482002876	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482002877	PS00402 Binding-protein-dependent transport systems inner membrane comp. sign.
553482002878	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
553482002879	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
553482002880	Walker A/P-loop; other site
553482002881	ATP binding site [chemical binding]; other site
553482002882	Q-loop/lid; other site
553482002883	ABC transporter signature motif; other site
553482002884	Walker B; other site
553482002885	D-loop; other site
553482002886	H-loop/switch region; other site
553482002887	HMMPfam hit to PF00005, ABC transporter, score 5.8e-69
553482002888	PS00017 ATP/GTP-binding site motif A (P-loop).
553482002889	PS00211 ABC transporters family signature.
553482002890	phosphoglucomutase-2-like protein; Provisional; Region: PTZ00150
553482002891	This CD includes PGM2 (phosphoglucomutase 2) and PGM2L1 (phosphoglucomutase 2-like 1). The mammalian PGM2 is thought to be a phosphopentomutase that catalyzes the conversion of the nucleoside breakdown products, ribose-1-phosphate and...; Region: PGM2; cd05799
553482002892	active site
553482002893	substrate binding site [chemical binding]; other site
553482002894	metal binding site [ion binding]; metal-binding site
553482002895	HMMPfam hit to PF02878, Phosphoglucomutase/phosphomannomutase, al, score 1.1e-56
553482002896	PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature.
553482002897	HMMPfam hit to PF02879, Phosphoglucomutase/phosphomannomutase, al, score 0.017
553482002898	HMMPfam hit to PF02880, Phosphoglucomutase/phosphomannomutase, al, score 0.012
553482002899	HMMPfam hit to PF00408, Phosphoglucomutase/phosphomannomutase, C-, score 0.029
553482002900	bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase; Provisional; Region: PRK14179
553482002901	Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain; Region: THF_DHG_CYH; pfam00763
553482002902	NADP binding domain of methylene-tetrahydrofolate dehydrogenase/cyclohydrolase; Region: NAD_bind_m-THF_DH_Cyclohyd; cd01080
553482002903	homodimer interface [polypeptide binding]; other site
553482002904	NADP binding site [chemical binding]; other site
553482002905	substrate binding site [chemical binding]; other site
553482002906	HMMPfam hit to PF00763, Tetrahydrofolate dehydrogenase/cyclohyd, score 1.2e-66
553482002907	PS00766 Tetrahydrofolate dehydrogenase/cyclohydrolase signature 1.
553482002908	HMMPfam hit to PF02882, Tetrahydrofolate dehydrogenase/cyclohyd, score 9.8e-110
553482002909	PS00767 Tetrahydrofolate dehydrogenase/cyclohydrolase signature 2.
553482002910	B.subtilis YXKO protein of unknown function and related proteins. Based on the conservation of the ATP binding site, the substrate binding site and the Mg2+binding site and structural homology this group is a member of the ribokinase-like superfamily; Region: YXKO-related; cd01171
553482002911	putative substrate binding site [chemical binding]; other site
553482002912	putative ATP binding site [chemical binding]; other site
553482002913	1 transmembrane helix predicted for SEQ0639 by TMHMM2.0 at aa 24-46
553482002914	HMMPfam hit to PF01256, Carbohydrate kinase, score 2.3e-66
553482002915	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482002916	PS01050 Uncharacterized protein family UPF0031 signature 2.
553482002917	exodeoxyribonuclease VII large subunit; Reviewed; Region: xseA; PRK00286
553482002918	ExoVII_LU_OBF: A subfamily of OB folds corresponding to the N-terminal OB-fold domain of Escherichia coli exodeoxyribonuclease VII (ExoVII) large subunit. E. coli ExoVII is composed of two non-identical subunits. E. coli ExoVII is a...; Region: ExoVII_LU_OBF; cd04489
553482002919	generic binding surface II; other site
553482002920	generic binding surface I; other site
553482002921	HMMPfam hit to PF01336, OB-fold nucleic acid binding domain, score 2.3e-14
553482002922	HMMPfam hit to PF02601, Exonuclease VII, large subunit, score 8.5e-42
553482002923	exodeoxyribonuclease VII small subunit; Provisional; Region: PRK00977
553482002924	HMMPfam hit to PF02609, Exonuclease VII small subunit, score 1.1e-28
553482002925	Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; Region: IspA; COG0142
553482002926	Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685
553482002927	substrate binding pocket [chemical binding]; other site
553482002928	chain length determination region; other site
553482002929	substrate-Mg2+ binding site; other site
553482002930	catalytic residues [active]
553482002931	aspartate-rich region 1; other site
553482002932	active site lid residues [active]
553482002933	aspartate-rich region 2; other site
553482002934	HMMPfam hit to PF00348, Polyprenyl synthetase, score 1.9e-61
553482002935	PS00723 Polyprenyl synthetases signature 1.
553482002936	PS00444 Polyprenyl synthetases signature 2.
553482002937	Predicted rRNA methylase [Translation, ribosomal structure and biogenesis]; Region: COG1189
553482002938	S4 RNA-binding domain; Region: S4; smart00363
553482002939	FtsJ-like methyltransferase; Region: FtsJ; pfam01728
553482002940	HMMPfam hit to PF01479, S4 domain, score 0.013
553482002941	HMMPfam hit to PF01728, FtsJ-like methyltransferase, score 0.00016
553482002942	Arginine repressor [Transcription]; Region: ArgR; COG1438
553482002943	Arginine repressor, DNA binding domain; Region: Arg_repressor; pfam01316
553482002944	HMMPfam hit to PF01316, Arginine repressor, DNA binding domai, score 1.9e-24
553482002945	HMMPfam hit to PF02863, Arginine repressor, C-terminal domain, score 5.2e-19
553482002946	ATPase involved in DNA repair [DNA replication, recombination, and repair]; Region: RecN; COG0497
553482002947	ATP-binding cassette domain of RecN; Region: ABC_RecN; cd03241
553482002948	Walker A/P-loop; other site
553482002949	ATP binding site [chemical binding]; other site
553482002950	Q-loop/lid; other site
553482002951	ATP-binding cassette domain of RecN; Region: ABC_RecN; cd03241
553482002952	Q-loop/lid; other site
553482002953	ABC transporter signature motif; other site
553482002954	Walker B; other site
553482002955	D-loop; other site
553482002956	H-loop/switch region; other site
553482002957	HMMPfam hit to PF02463, RecF/RecN/SMC N terminal domain, score 2.8e-11
553482002958	PS00017 ATP/GTP-binding site motif A (P-loop).
553482002959	PS00343 Gram-positive cocci surface proteins 'anchoring' hexapeptide.
553482002960	EDD domain protein, DegV family; Region: DegV; TIGR00762
553482002961	Uncharacterized protein, DegV family COG1307; Region: DegV; pfam02645
553482002962	HMMPfam hit to PF02645, Uncharacterized protein, DegV family COG1307, score 3.6e-69
553482002963	Members of the SGNH-hydrolase superfamily, a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely...; Region: SGNH_hydrolase_YpmR_like; cd04506
553482002964	active site
553482002965	catalytic triad [active]
553482002966	oxyanion hole [active]
553482002967	1 transmembrane helix predicted for SEQ0648 by TMHMM2.0 at aa 5-27
553482002968	HMMPfam hit to PF00657, GDSL-like Lipase/Acylhydrolase, score 4.8e-22
553482002969	Uncharacterized protein conserved in bacteria (DUF2140); Region: DUF2140; cl11548
553482002970	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
553482002971	IHF dimer interface [polypeptide binding]; other site
553482002972	IHF - DNA interface [nucleotide binding]; other site
553482002973	HMMPfam hit to PF00216, Bacterial DNA-binding protein, score 1.1e-51
553482002974	PS00045 Bacterial histone-like DNA-binding proteins signature.
553482002975	ADP-ribosyltransferase exoenzyme; Region: ADPrib_exo_Tox; pfam03496
553482002976	active site
553482002977	conformational flexibility of ligand binding pocket; other site
553482002978	ADP-ribosylating toxin turn-turn motif; other site
553482002979	HMMPfam hit to PF03496, Clostridial binary toxin A, score 5.6e-09
553482002980	1 transmembrane helix predicted for SEQ0651 by TMHMM2.0 at aa 15-32
553482002981	H+ Antiporter protein; Region: 2A0121; TIGR00900
553482002982	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
553482002983	10 transmembrane helices predicted for SEQ0652 by TMHMM2.0 at aa 71-90, 94-116, 137-156, 160-182, 218-240, 255-274, 281-300, 304-326, 338-360 and 370-392
553482002984	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
553482002985	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
553482002986	non-specific DNA binding site [nucleotide binding]; other site
553482002987	salt bridge; other site
553482002988	sequence-specific DNA binding site [nucleotide binding]; other site
553482002989	transcriptional activator, Rgg/GadR/MutR family, C-terminal domain; Region: RGG_Cterm; TIGR01716
553482002990	HMMPfam hit to PF01381, Helix-turn-helix, score 2.9e-06
553482002991	1 transmembrane helix predicted for SEQ0654 by TMHMM2.0 at aa 4-24
553482002992	dihydroorotate dehydrogenase (subfamily 1) family protein; Region: pyrD_sub1_fam; TIGR01037
553482002993	Dihydroorotate dehydrogenase (DHOD) class 1A FMN-binding domain. DHOD catalyzes the oxidation of (S)-dihydroorotate to orotate. This is the fourth step and the only redox reaction in the de novo biosynthesis of UMP, the precursor of all pyrimidine...; Region: DHOD_1A_like; cd04741
553482002994	active site
553482002995	FMN binding site [chemical binding]; other site
553482002996	substrate binding site [chemical binding]; other site
553482002997	catalytic residues [active]
553482002998	homodimer interface [polypeptide binding]; other site
553482002999	HMMPfam hit to PF01180, Dihydroorotate dehydrogenase, score 9.9e-110
553482003000	PS00912 Dihydroorotate dehydrogenase signature 2.
553482003001	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
553482003002	catalytic core [active]
553482003003	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
553482003004	HMMPfam hit to PF00300, Phosphoglycerate mutase family, score 1.9e-44
553482003005	Predicted small molecule binding protein (contains 3H domain) [General function prediction only]; Region: COG1827
553482003006	HTH domain; Region: HTH_11; pfam08279
553482003007	3H domain; Region: 3H; pfam02829
553482003008	HMMPfam hit to PF08279, HTH domain, score 1.2e-15
553482003009	Predicted helix-turn-helix motif with score 1167.000, SD 3.16 at aa 21-42, sequence ISATSLAKALGVSRQVIVGDIA
553482003010	HMMPfam hit to PF02829, 3H domain, score 2.8e-24
553482003011	5 transmembrane helices predicted for SEQ0658 by TMHMM2.0 at aa 10-32, 45-67, 72-94, 107-129 and 144-166
553482003012	Formate/nitrite family of transporters [Inorganic ion transport and metabolism]; Region: FocA; COG2116
553482003013	HMMPfam hit to PF01226, Formate/nitrite transporter, score 7.8e-39
553482003014	6 transmembrane helices predicted for SEQ0659 by TMHMM2.0 at aa 23-45, 60-82, 103-125, 156-178, 191-213 and 223-245
553482003015	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482003016	PS01005 Formate and nitrite transporters signature 1.
553482003017	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482003018	PS00213 Lipocalin signature.
553482003019	Cell division protein FtsI/penicillin-binding protein 2 [Cell envelope biogenesis, outer membrane]; Region: FtsI; COG0768
553482003020	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
553482003021	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
553482003022	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
553482003023	1 transmembrane helix predicted for SEQ0660 by TMHMM2.0 at aa 16-35
553482003024	HMMPfam hit to PF03717, Penicillin-binding Protein dimerisatio, score 1.3e-37
553482003025	HMMPfam hit to PF00905, Penicillin binding protein transpeptid, score 8.7e-86
553482003026	recombination protein RecR; Reviewed; Region: recR; PRK00076
553482003027	RecR protein; Region: RecR; pfam02132
553482003028	TOPRIM_recR: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in Escherichia coli RecR.  RecR participates in the RecFOR pathway of homologous recombinational repair in prokaryotes. This pathway provides a...; Region: TOPRIM_recR; cd01025
553482003029	putative active site [active]
553482003030	putative metal-binding site [ion binding]; other site
553482003031	tetramer interface [polypeptide binding]; other site
553482003032	HMMPfam hit to PF02132, RecR protein, score 7.6e-20
553482003033	PS01300 RecR protein signature.
553482003034	HMMPfam hit to PF01751, Toprim domain, score 3e-16
553482003035	D-alanyl-alanine synthetase A; Reviewed; Region: ddl; PRK01966
553482003036	D-ala D-ala ligase N-terminus; Region: Dala_Dala_lig_N; pfam01820
553482003037	ATP-grasp domain; Region: ATP-grasp_4; cl17255
553482003038	HMMPfam hit to PF01820, D-ala D-ala ligase N-terminus, score 3.6e-36
553482003039	PS00843 D-alanine--D-alanine ligase signature 1.
553482003040	HMMPfam hit to PF07478, D-ala D-ala ligase C-terminus, score 1.3e-94
553482003041	HMMPfam hit to PF02222, ATP-grasp domain, score 0.002
553482003042	PS00844 D-alanine--D-alanine ligase signature 2.
553482003043	putative transposase OrfB; Reviewed; Region: PHA02517
553482003044	HTH-like domain; Region: HTH_21; pfam13276
553482003045	Integrase core domain; Region: rve; pfam00665
553482003046	Integrase core domain; Region: rve_2; pfam13333
553482003047	HMMPfam hit to PF00665, Integrase core domain, score 8.8e-38
553482003048	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
553482003049	Helix-turn-helix domain; Region: HTH_28; pfam13518
553482003050	HMMPfam hit to PF01527, Transposase, score 0.00062
553482003051	HMMPfam hit to PF02178, no description, score 0.21
553482003052	Predicted helix-turn-helix motif with score 1140.000, SD 3.07 at aa 19-40, sequence KSIKCLSEKFSIAESDLKYMIR
553482003053	UDP-N-acetylmuramyl pentapeptide synthase [Cell envelope biogenesis, outer membrane]; Region: MurF; COG0770
553482003054	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
553482003055	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
553482003056	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
553482003057	HMMPfam hit to PF01225, Mur ligase family, catalytic domain, score 1.2e-11
553482003058	HMMPfam hit to PF08245, Mur ligase middle domain, score 9.4e-52
553482003059	HMMPfam hit to PF02875, Mur ligase family, glutamate ligase doma, score 5.2e-07
553482003060	conserved hypothetical integral membrane protein TIGR02206; Region: intg_mem_TP0381
553482003061	5 transmembrane helices predicted for SEQ0668 by TMHMM2.0 at aa 11-33, 46-65, 121-143, 156-175 and 195-217
553482003062	peptide chain release factor 3; Provisional; Region: prfC; PRK00741
553482003063	Release Factor 3 (RF3) protein involved in the terminal step of translocation in bacteria; Region: RF3; cd04169
553482003064	G1 box; other site
553482003065	putative GEF interaction site [polypeptide binding]; other site
553482003066	GTP/Mg2+ binding site [chemical binding]; other site
553482003067	Switch I region; other site
553482003068	G2 box; other site
553482003069	G3 box; other site
553482003070	Switch II region; other site
553482003071	G4 box; other site
553482003072	G5 box; other site
553482003073	RF3_II: this subfamily represents the domain II of bacterial Release Factor 3 (RF3). Termination of protein synthesis by the ribosome requires two release factor (RF) classes. The class II RF3 is a GTPase that removes class I RFs (RF1 or RF2) from the...; Region: RF3_II; cd03689
553482003074	HMMPfam hit to PF00009, Elongation factor Tu GTP binding domain, score 1e-66
553482003075	PS00301 GTP-binding elongation factors signature.
553482003076	HMMPfam hit to PF03144, Elongation factor Tu domain, score 4.5e-13
553482003077	PS00732 Ribosomal protein S16 signature.
553482003078	ATP-dependent RNA helicase SrmB; Provisional; Region: PRK11192
553482003079	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
553482003080	ATP binding site [chemical binding]; other site
553482003081	Mg++ binding site [ion binding]; other site
553482003082	motif III; other site
553482003083	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
553482003084	nucleotide binding region [chemical binding]; other site
553482003085	ATP-binding site [chemical binding]; other site
553482003086	HMMPfam hit to PF00270, DEAD/DEAH box helicase, score 2.5e-72
553482003087	PS00017 ATP/GTP-binding site motif A (P-loop).
553482003088	PS00039 DEAD-box subfamily ATP-dependent helicases signature.
553482003089	HMMPfam hit to PF00271, Helicase conserved C-terminal domain, score 6.9e-35
553482003090	K+ potassium transporter; Region: K_trans; cl15781
553482003091	12 transmembrane helices predicted for SEQ0671 by TMHMM2.0 at aa 12-34, 54-76, 103-125, 140-162, 169-191, 220-242, 249-271, 291-313, 334-356, 371-393, 400-422 and 426-448
553482003092	HMMPfam hit to PF02705, K+ potassium transporter, score 1.4e-37
553482003093	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482003094	putative transposase OrfB; Reviewed; Region: PHA02517
553482003095	HTH-like domain; Region: HTH_21; pfam13276
553482003096	Integrase core domain; Region: rve; pfam00665
553482003097	Integrase core domain; Region: rve_2; pfam13333
553482003098	HMMPfam hit to PF00665, Integrase core domain, score 8.8e-38
553482003099	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
553482003100	Helix-turn-helix domain; Region: HTH_28; pfam13518
553482003101	HMMPfam hit to PF01527, Transposase, score 0.00062
553482003102	HMMPfam hit to PF02178, no description, score 0.21
553482003103	Predicted helix-turn-helix motif with score 1140.000, SD 3.07 at aa 19-40, sequence KSIKCLSEKFSIAESDLKYMIR
553482003104	The GIY-YIG domain of uncharacterized protein family UPF0213 related to structure-specific endonuclease SLX1; Region: GIY-YIG_UPF0213; cd10456
553482003105	GIY-YIG motif/motif A; other site
553482003106	putative active site [active]
553482003107	putative metal binding site [ion binding]; other site
553482003108	HMMPfam hit to PF01541, GIY-YIG catalytic domain, score 7e-23
553482003109	Predicted O-methyltransferase [General function prediction only]; Region: COG4123
553482003110	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
553482003111	S-adenosylmethionine binding site [chemical binding]; other site
553482003112	HMMPfam hit to PF05175, Methyltransferase small domain, score 5.3e-05
553482003113	PS00092 N-6 Adenine-specific DNA methylases signature.
553482003114	1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid metabolism]; Region: PlsC; COG0204
553482003115	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989
553482003116	putative acyl-acceptor binding pocket; other site
553482003117	2 transmembrane helices predicted for SEQ0676 by TMHMM2.0 at aa 12-34 and 228-250
553482003118	HMMPfam hit to PF01553, Acyltransferase, score 3.9e-25
553482003119	SLBB domain; Region: SLBB; pfam10531
553482003120	comEA protein; Region: comE; TIGR01259
553482003121	1 transmembrane helix predicted for SEQ0677 by TMHMM2.0 at aa 17-39
553482003122	Predicted membrane metal-binding protein [General function prediction only]; Region: ComEC; COG0658
553482003123	Domain of unknown function (DUF4131); Region: DUF4131; pfam13567
553482003124	Competence protein; Region: Competence; pfam03772
553482003125	Predicted hydrolase (metallo-beta-lactamase superfamily) [General function prediction only]; Region: ComEC; COG2333
553482003126	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
553482003127	9 transmembrane helices predicted for SEQ0678 by TMHMM2.0 at aa 5-27, 32-51, 236-255, 270-292, 319-341, 370-392, 399-421, 436-458 and 465-487
553482003128	HMMPfam hit to PF03772, Competence protein, score 1.3e-38
553482003129	DNA polymerase III subunit delta; Reviewed; Region: holA; PRK05574
553482003130	DNA polymerase III, delta subunit; Region: DNA_pol3_delta; pfam06144
553482003131	HMMPfam hit to PF06144, DNA polymerase III, delta subunit, score 2e-115
553482003132	Superoxide dismutase [Inorganic ion transport and metabolism]; Region: SodA; COG0605
553482003133	Iron/manganese superoxide dismutases, alpha-hairpin domain; Region: Sod_Fe_N; pfam00081
553482003134	Iron/manganese superoxide dismutases, C-terminal domain; Region: Sod_Fe_C; pfam02777
553482003135	HMMPfam hit to PF00081, Iron/manganese superoxide dismutases, alpha-, score 2.2e-42
553482003136	HMMPfam hit to PF02777, Iron/manganese superoxide dismutases, C-term, score 3e-61
553482003137	PS00088 Manganese and iron superoxide dismutases signature.
553482003138	Protein of unknown function (DUF3114); Region: DUF3114; pfam11311
553482003139	S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Provisional; Region: queA; PRK00147
553482003140	S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Region: queA; TIGR00113
553482003141	HMMPfam hit to PF02547, Queuosine biosynthesis protein, score 6.3e-118
553482003142	6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase [Carbohydrate transport and metabolism]; Region: NagB; COG0363
553482003143	GlcN6P_deaminase: Glucosamine-6-phosphate (GlcN6P) deaminase subfamily; GlcN6P deaminase catalyzes the reversible conversion of GlcN6P to D-fructose-6-phosphate (Fru6P) and ammonium. The reaction is an aldo-keto isomerization coupled with an amination or...; Region: GlcN6P_deaminase; cd01399
553482003144	active site
553482003145	trimer interface [polypeptide binding]; other site
553482003146	allosteric site; other site
553482003147	active site lid [active]
553482003148	hexamer (dimer of trimers) interface [polypeptide binding]; other site
553482003149	HMMPfam hit to PF01182, Glucosamine-6-phosphate isomerases/6-, score 6.8e-41
553482003150	16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases [Translation, ribosomal structure and biogenesis]; Region: RsuA; COG1187
553482003151	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
553482003152	RNA binding surface [nucleotide binding]; other site
553482003153	Pseudouridine synthase, Escherichia coli RsuA like; Region: PseudoU_synth_RsuA; cd02553
553482003154	active site
553482003155	uracil binding [chemical binding]; other site
553482003156	HMMPfam hit to PF01479, S4 domain, score 2.5e-07
553482003157	HMMPfam hit to PF00849, RNA pseudouridylate synthase, score 7.2e-15
553482003158	PS01149 Rsu family of pseudouridine synthase signature.
553482003159	HMMPfam hit to PF06054, Competence protein CoiA-like family, score 4.7e-27
553482003160	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
553482003161	Helix-turn-helix domain; Region: HTH_28; pfam13518
553482003162	Predicted helix-turn-helix motif with score 1140.000, SD 3.07 at aa 19-40, sequence KSIKCLSEKFSIAESDLKYMIR
553482003163	HMMPfam hit to PF01527, Transposase, score 0.00062
553482003164	HMMPfam hit to PF02178, no description, score 0.21
553482003165	putative transposase OrfB; Reviewed; Region: PHA02517
553482003166	HTH-like domain; Region: HTH_21; pfam13276
553482003167	Integrase core domain; Region: rve; pfam00665
553482003168	Integrase core domain; Region: rve_2; pfam13333
553482003169	HMMPfam hit to PF00665, Integrase core domain, score 1.1e-37
553482003170	Oligoendopeptidase F [Amino acid transport and metabolism]; Region: COG1164
553482003171	Peptidase family M3B Oligopeptidase F (PepF); Region: M3B_PepF_3; cd09608
553482003172	active site
553482003173	Zn binding site [ion binding]; other site
553482003174	HMMPfam hit to PF08439, Oligopeptidase F, score 1.2e-24
553482003175	HMMPfam hit to PF01432, Peptidase family M3, score 6e-148
553482003176	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
553482003177	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
553482003178	Coenzyme A binding pocket [chemical binding]; other site
553482003179	HMMPfam hit to PF00583, Acetyltransferase (GNAT) family, score 1.6e-10
553482003180	haloacid dehalogenase-like hydrolase; Region: Hydrolase; pfam00702
553482003181	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
553482003182	motif II; other site
553482003183	HMMPfam hit to PF00702, haloacid dehalogenase-like hydrolase, score 4.4e-22
553482003184	beta-phosphoglucomutase family hydrolase; Region: PGMB-YQAB-SF; TIGR02009
553482003185	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
553482003186	motif II; other site
553482003187	HMMPfam hit to PF00702, haloacid dehalogenase-like hydrolase, score 8.1e-25
553482003188	Predicted O-methyltransferase [General function prediction only]; Region: COG4122
553482003189	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
553482003190	S-adenosylmethionine binding site [chemical binding]; other site
553482003191	HMMPfam hit to PF01596, O-methyltransferase, score 6.8e-13
553482003192	HMMPfam hit to PF08241, Methyltransferase domain, score 6.2e-09
553482003193	HMMPfam hit to PF08242, Methyltransferase domain, score 6e-05
553482003194	foldase protein PrsA; Reviewed; Region: PRK12450
553482003195	SurA N-terminal domain; Region: SurA_N; pfam09312
553482003196	PPIC-type PPIASE domain; Region: Rotamase_2; pfam13145
553482003197	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482003198	alanyl-tRNA synthetase; Reviewed; Region: alaS; PRK00252
553482003199	Alanyl-tRNA synthetase (AlaRS) class II core catalytic domain. AlaRS is a homodimer. It is responsible for the attachment of alanine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: AlaRS_core; cd00673
553482003200	motif 1; other site
553482003201	active site
553482003202	motif 2; other site
553482003203	motif 3; other site
553482003204	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; smart00863
553482003205	DHHA1 domain; Region: DHHA1; pfam02272
553482003206	HMMPfam hit to PF01411, tRNA synthetases class II (A), score 5.3e-260
553482003207	PS00339 Aminoacyl-transfer RNA synthetases class-II signature 2.
553482003208	HMMPfam hit to PF07973, Threonyl and Alanyl tRNA synthetase seco, score 5.8e-23
553482003209	HMMPfam hit to PF02272, DHHA1 domain, score 4.8e-15
553482003210	DNA/RNA non-specific endonuclease; Region: Endonuclea_NS_2; cl17626
553482003211	DNA/RNA non-specific endonuclease; Region: Endonuclease_NS; smart00892
553482003212	HMMPfam hit to PF01223, DNA/RNA non-specific endonuclease, score 4.5e-31
553482003213	Predicted xylanase/chitin deacetylase [Carbohydrate transport and metabolism]; Region: CDA1; COG0726
553482003214	Catalytic NodB homology domain of Streptococcus pneumoniae peptidoglycan deacetylase PgdA, Bacillus subtilis BsYjeA protein, and their bacterial homologs; Region: CE4_SpPgdA_BsYjeA_like; cd10947
553482003215	NodB motif; other site
553482003216	active site
553482003217	catalytic site [active]
553482003218	Zn binding site [ion binding]; other site
553482003219	1 transmembrane helix predicted for SEQ0697 by TMHMM2.0 at aa 5-27
553482003220	HMMPfam hit to PF01522, Polysaccharide deacetylase, score 2.8e-52
553482003221	Superfamily II DNA and RNA helicases [DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis]; Region: SrmB; COG0513
553482003222	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cl17251
553482003223	ATP binding site [chemical binding]; other site
553482003224	putative Mg++ binding site [ion binding]; other site
553482003225	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
553482003226	nucleotide binding region [chemical binding]; other site
553482003227	ATP-binding site [chemical binding]; other site
553482003228	HMMPfam hit to PF00271, Helicase conserved C-terminal domain, score 1.5e-25
553482003229	HMMPfam hit to PF00270, DEAD/DEAH box helicase, score 1.7e-36
553482003230	Uridine kinase [Nucleotide transport and metabolism]; Region: Udk; COG0572
553482003231	Uridine monophosphate kinase (UMPK, EC 2.7.1.48), also known as uridine kinase or uridine-cytidine kinase (UCK), catalyzes the reversible phosphoryl transfer from ATP to uridine or cytidine to yield UMP or CMP. In the primidine nucleotide-salvage pathway; Region: UMPK; cd02023
553482003232	Sugar specificity; other site
553482003233	Pyrimidine base specificity; other site
553482003234	ATP-binding site [chemical binding]; other site
553482003235	HMMPfam hit to PF00485, Phosphoribulokinase / Uridine kinase family, score 3.7e-54
553482003236	PS00017 ATP/GTP-binding site motif A (P-loop).
553482003237	Predicted membrane protein [Function unknown]; Region: COG3326
553482003238	3 transmembrane helices predicted for SEQ0700 by TMHMM2.0 at aa 13-32, 47-69 and 76-98
553482003239	HMMPfam hit to PF06961, Protein of unknown function (DUF1294), score 7.6e-29
553482003240	Membrane proteinase, regulator of anti-sigma factor [Posttranslational modification, protein turnover, chaperones]; Region: prsW; COG2339
553482003241	6 transmembrane helices predicted for SEQ0701 by TMHMM2.0 at aa 9-31, 41-63, 75-97, 117-139, 191-208 and 237-259
553482003242	GAF domain-containing protein [Signal transduction mechanisms]; Region: COG1956
553482003243	DNA polymerase III subunits gamma and tau; Validated; Region: PRK05563
553482003244	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
553482003245	Walker A motif; other site
553482003246	ATP binding site [chemical binding]; other site
553482003247	Walker B motif; other site
553482003248	arginine finger; other site
553482003249	DNA polymerase III subunits gamma and tau domain III; Region: DNA_pol3_gamma3; pfam12169
553482003250	HMMPfam hit to PF00004, ATPase family associated with various cellul, score 9.3e-11
553482003251	PS00017 ATP/GTP-binding site motif A (P-loop).
553482003252	Biotin operon repressor [Transcription]; Region: BirA; COG1654
553482003253	bifunctional biotin--[acetyl-CoA-carboxylase] synthetase/biotin operon repressor; Provisional; Region: PRK11886
553482003254	Biotin/lipoate A/B protein ligase family; Region: BPL_LplA_LipB; pfam03099
553482003255	Biotin protein ligase C terminal domain; Region: BPL_C; pfam02237
553482003256	HMMPfam hit to PF02237, Biotin protein ligase C terminal domain, score 1.7e-09
553482003257	HMMPfam hit to PF03099, Biotin/lipoate A/B protein ligase famil, score 0.0025
553482003258	HMMPfam hit to PF08279, HTH domain, score 4.4e-16
553482003259	Predicted helix-turn-helix motif with score 1186.000, SD 3.23 at aa 18-39, sequence VSGEYLAEQLKLSRTSVWKSIK
553482003260	streptococcal histidine triad protein; Region: strep_his_triad; TIGR01363
553482003261	Streptococcal histidine triad protein; Region: Strep_his_triad; pfam04270
553482003262	Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799
553482003263	Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799
553482003264	Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; Region: LRR_RI; cl15309
553482003265	Substrate binding site [chemical binding]; other site
553482003266	Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799
553482003267	Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799
553482003268	Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799
553482003269	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482003270	HMMPfam hit to PF04270, Streptococcal histidine triad protein, score 0.034
553482003271	HMMPfam hit to PF04270, Streptococcal histidine triad protein, score 0.00026
553482003272	HMMPfam hit to PF04270, Streptococcal histidine triad protein, score 0.016
553482003273	HMMPfam hit to PF00560, Leucine Rich Repeat, score 2
553482003274	HMMPfam hit to PF00560, Leucine Rich Repeat, score 7
553482003275	S-adenosylmethionine synthetase; Validated; Region: PRK05250
553482003276	S-adenosylmethionine synthetase, N-terminal domain; Region: S-AdoMet_synt_N; pfam00438
553482003277	S-adenosylmethionine synthetase, central domain; Region: S-AdoMet_synt_M; pfam02772
553482003278	S-adenosylmethionine synthetase, C-terminal domain; Region: S-AdoMet_synt_C; pfam02773
553482003279	HMMPfam hit to PF00438, S-adenosylmethionine synthetase, N-te, score 2.4e-48
553482003280	HMMPfam hit to PF02772, S-adenosylmethionine synthetase, cent, score 1e-78
553482003281	PS00376 S-adenosylmethionine synthetase signature 1.
553482003282	HMMPfam hit to PF02773, S-adenosylmethionine synthetase, C-te, score 1.5e-82
553482003283	PS00377 S-adenosylmethionine synthetase signature 2.
553482003284	UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Region: murA; TIGR01072
553482003285	UDP-N-acetylglucosamine enolpyruvyl transferase catalyzes enolpyruvyl transfer as part of the first step in the biosynthesis of peptidoglycan, a component of the bacterial cell wall. The reaction is phosphoenolpyruvate + UDP-N-acetyl-D-glucosamine =...; Region: UdpNAET; cd01555
553482003286	hinge; other site
553482003287	active site
553482003288	HMMPfam hit to PF00275, EPSP synthase (3-phosphoshikimate 1-car, score 1.2e-100
553482003289	PS00017 ATP/GTP-binding site motif A (P-loop).
553482003290	PS00017 ATP/GTP-binding site motif A (P-loop).
553482003291	putative transposase OrfB; Reviewed; Region: PHA02517
553482003292	HTH-like domain; Region: HTH_21; pfam13276
553482003293	Integrase core domain; Region: rve; pfam00665
553482003294	Integrase core domain; Region: rve_2; pfam13333
553482003295	HMMPfam hit to PF00665, Integrase core domain, score 1.1e-37
553482003296	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
553482003297	Helix-turn-helix domain; Region: HTH_28; pfam13518
553482003298	HMMPfam hit to PF01527, Transposase, score 0.00062
553482003299	HMMPfam hit to PF02178, no description, score 0.21
553482003300	Predicted helix-turn-helix motif with score 1140.000, SD 3.07 at aa 19-40, sequence KSIKCLSEKFSIAESDLKYMIR
553482003301	MFS/sugar transport protein; Region: MFS_2; pfam13347
553482003302	melibiose:sodium symporter; Provisional; Region: PRK10429; cl15392
553482003303	11 transmembrane helices predicted for SEQ0711 by TMHMM2.0 at aa 34-56, 91-113, 117-134, 155-177, 192-214, 255-277, 287-306, 313-335, 345-364, 404-426 and 441-463
553482003304	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
553482003305	2-keto-3-deoxygluconate kinase (KdgK) phosphorylates 2-keto-3-deoxygluconate (KDG) to form 2-keto-3-deoxy-6-phosphogluconate (KDGP). KDG is the common intermediate product, that allows organisms to channel D-glucuronate and/or D-galacturinate into the...; Region: KdgK; cd01166
553482003306	substrate binding site [chemical binding]; other site
553482003307	ATP binding site [chemical binding]; other site
553482003308	HMMPfam hit to PF00294, pfkB family carbohydrate kinase, score 3.4e-16
553482003309	beta-D-glucuronidase; Provisional; Region: PRK10150
553482003310	Glycosyl hydrolases family 2, sugar binding domain; Region: Glyco_hydro_2_N; pfam02837
553482003311	Glycosyl hydrolases family 2; Region: Glyco_hydro_2; pfam00703
553482003312	Glycosyl hydrolases family 2, TIM barrel domain; Region: Glyco_hydro_2_C; pfam02836
553482003313	HMMPfam hit to PF02837, Glycosyl hydrolases family 2, sugar b, score 4.7e-42
553482003314	HMMPfam hit to PF00703, Glycosyl hydrolases family 2, immunog, score 2.3e-12
553482003315	HMMPfam hit to PF02836, Glycosyl hydrolases family 2, TIM bar, score 4.8e-93
553482003316	PS00719 Glycosyl hydrolases family 2 signature 1.
553482003317	Transcriptional regulators [Transcription]; Region: FadR; COG2186
553482003318	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
553482003319	DNA-binding site [nucleotide binding]; DNA binding site
553482003320	FCD domain; Region: FCD; pfam07729
553482003321	HMMPfam hit to PF00392, Bacterial regulatory proteins, gntR family, score 2.5e-18
553482003322	PS00043 Bacterial regulatory proteins, gntR family signature.
553482003323	Predicted helix-turn-helix motif with score 1121.000, SD 3.00 at aa 29-50, sequence PNEYELAQDLEVGRSTIREAVR
553482003324	HMMPfam hit to PF07729, FCD domain, score 2.4e-31
553482003325	2-keto-3-deoxy-6-phosphogluconate aldolase [Carbohydrate transport and metabolism]; Region: Eda; COG0800
553482003326	KDPG and KHG aldolase; Region: KDPG_aldolase; cd00452
553482003327	active site
553482003328	intersubunit interface [polypeptide binding]; other site
553482003329	catalytic residue [active]
553482003330	HMMPfam hit to PF01081, KDPG and KHG aldolase, score 2.9e-31
553482003331	Glucuronate isomerase; Region: UxaC; pfam02614
553482003332	Glucuronate isomerase [Carbohydrate transport and metabolism]; Region: UxaC; COG1904
553482003333	HMMPfam hit to PF02614, Glucuronate isomerase, score 1.2e-165
553482003334	mannonate dehydratase; Provisional; Region: PRK03906
553482003335	mannonate dehydratase; Region: uxuA; TIGR00695
553482003336	HMMPfam hit to PF03786, D-mannonate dehydratase (UxuA), score 9.7e-183
553482003337	D-mannonate oxidoreductase; Provisional; Region: PRK08277
553482003338	putative D-mannonate oxidoreductase, classical (c) SDR; Region: mannonate_red_SDR_c; cd08935
553482003339	putative NAD(P) binding site [chemical binding]; other site
553482003340	active site
553482003341	HMMPfam hit to PF00106, short chain dehydrogenase, score 2.8e-10
553482003342	PS00061 Short-chain dehydrogenases/reductases family signature.
553482003343	haloacid dehalogenase-like hydrolase; Region: Hydrolase; pfam00702
553482003344	HMMPfam hit to PF00702, haloacid dehalogenase-like hydrolase, score 0.00022
553482003345	Beta-glucosidase-related glycosidases [Carbohydrate transport and metabolism]; Region: BglX; COG1472
553482003346	Glycosyl hydrolase family 3 N terminal domain; Region: Glyco_hydro_3; cl07971
553482003347	HMMPfam hit to PF00933, Glycosyl hydrolase family 3 N terminal, score 7.8e-22
553482003348	YSIRK type signal peptide; Region: YSIRK_signal; cl04650
553482003349	GA module; Region: GA; pfam01468
553482003350	B domain; Region: IgG_binding_B; pfam01378
553482003351	B domain; Region: IgG_binding_B; pfam01378
553482003352	HMMPfam hit to PF01468, GA module, score 7.2e-17
553482003353	HMMPfam hit to PF01378, B domain, score 3.2e-29
553482003354	HMMPfam hit to PF01378, B domain, score 2.7e-34
553482003355	HMMPfam hit to PF00746, Gram positive anchor, score 1e-12
553482003356	PS00343 Gram-positive cocci surface proteins 'anchoring' hexapeptide.
553482003357	Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis]; Region: RimL; COG1670
553482003358	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
553482003359	HMMPfam hit to PF00583, Acetyltransferase (GNAT) family, score 2.9e-10
553482003360	Predicted transcriptional regulator containing CBS domains [Transcription]; Region: COG4109
553482003361	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
553482003362	DNA-binding site [nucleotide binding]; DNA binding site
553482003363	DRTGG domain; Region: DRTGG; pfam07085
553482003364	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with a DRTGG domain upstream. The function of the DRTGG domain, named after its conserved residues, is unknown. CBS is a small domain originally...; Region: CBS_pair_DRTGG_assoc; cd04596
553482003365	The hotdog fold was initially identified in the E. coli FabA (beta-hydroxydecanoyl-acyl carrier protein (ACP)-dehydratase) structure and subsequently in 4HBT (4-hydroxybenzoyl-CoA thioesterase) from Pseudomonas. A number of other seemingly unrelated...; Region: hot_dog; cd03440
553482003366	active site 2 [active]
553482003367	active site 1 [active]
553482003368	HMMPfam hit to PF00392, Bacterial regulatory proteins, gntR family, score 0.0045
553482003369	HMMPfam hit to PF08279, HTH domain, score 0.0038
553482003370	Predicted helix-turn-helix motif with score 1136.000, SD 3.06 at aa 20-41, sequence VSVRSISNHLKVSDGTAYRAIK
553482003371	HMMPfam hit to PF07085, DRTGG domain, score 2.1e-53
553482003372	HMMPfam hit to PF00571, CBS domain pair, score 1.7e-24
553482003373	Methionine Aminopeptidase 1. E.C. 3.4.11.18. Also known as methionyl aminopeptidase and Peptidase M. Catalyzes release of N-terminal amino acids, preferentially methionine, from peptides and arylamides; Region: MetAP1; cd01086
553482003374	active site
553482003375	HMMPfam hit to PF00557, metallopeptidase family M24, score 2.8e-39
553482003376	Ribonuclease BN family enzyme [Replication, recombination, and repair]; Region: Rbn; COG1295
553482003377	HMMPfam hit to PF03631, Ribonuclease BN-like family, score 2.4e-81
553482003378	5 transmembrane helices predicted for SEQ0725 by TMHMM2.0 at aa 35-57, 133-155, 183-205, 217-239 and 254-276
553482003379	3-phosphoshikimate 1-carboxyvinyltransferase; Provisional; Region: PRK02427
553482003380	EPSP synthase domain. 3-phosphoshikimate 1-carboxyvinyltransferase (5-enolpyruvylshikimate-3-phosphate synthase) (EC 2.5.1.19) catalyses the reaction between shikimate-3-phosphate (S3P) and phosphoenolpyruvate (PEP) to form...; Region: EPSP_synthase; cd01556
553482003381	hinge; other site
553482003382	active site
553482003383	HMMPfam hit to PF00275, EPSP synthase (3-phosphoshikimate 1-car, score 6.3e-137
553482003384	PS00104 EPSP synthase signature 1.
553482003385	PS00017 ATP/GTP-binding site motif A (P-loop).
553482003386	shikimate kinase; Reviewed; Region: aroK; PRK00131
553482003387	Shikimate kinase (SK) is the fifth enzyme in the shikimate pathway, a seven-step biosynthetic pathway which converts erythrose-4-phosphate to chorismic acid, found in bacteria, fungi and plants. Chorismic acid is a important intermediate in the synthesis...; Region: SK; cd00464
553482003388	ADP binding site [chemical binding]; other site
553482003389	magnesium binding site [ion binding]; other site
553482003390	putative shikimate binding site; other site
553482003391	PS00017 ATP/GTP-binding site motif A (P-loop).
553482003392	HMMPfam hit to PF01202, Shikimate kinase, score 7.6e-53
553482003393	PS01128 Shikimate kinase signature.
553482003394	Transcriptional regulator [Transcription]; Region: LytR; COG1316
553482003395	1 transmembrane helix predicted for SEQ0728 by TMHMM2.0 at aa 148-167
553482003396	HMMPfam hit to PF03816, Cell envelope-related transcriptional a, score 2.5e-79
553482003397	SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase [Translation, ribosomal structure and biogenesis]; Region: TrmA; COG2265
553482003398	TRAM domain; Region: TRAM; pfam01938
553482003399	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
553482003400	S-adenosylmethionine binding site [chemical binding]; other site
553482003401	HMMPfam hit to PF01938, TRAM domain, score 6e-09
553482003402	HMMPfam hit to PF05958, tRNA (Uracil-5-)-methyltransferase, score 8.8e-07
553482003403	ICESe1
553482003404	Replication initiator protein A (RepA) N-terminus; Region: RepA_N; pfam06970
553482003405	HMMPfam hit to PF06970, Replication initiator protein A (RepA) N-ter, score 6.6e-37
553482003406	hypothetical protein; Validated; Region: PRK08116
553482003407	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
553482003408	Walker A motif; other site
553482003409	ATP binding site [chemical binding]; other site
553482003410	Walker B motif; other site
553482003411	PS00190 Cytochrome c family heme-binding site signature.
553482003412	PS00017 ATP/GTP-binding site motif A (P-loop).
553482003413	Protein of unknown function (DUF3801); Region: DUF3801; pfam12687
553482003414	CDS contains a frameshifts after codons 94 and 480
553482003415	2 transmembrane helices predicted for SEQ0733 by TMHMM2.0 at aa 21-43 and 69-91
553482003416	PS00017 ATP/GTP-binding site motif A (P-loop).
553482003417	Replication protein A, class 2b aminoacyl-tRNA synthetases, and related proteins with oligonucleotide/oligosaccharide (OB) fold; Region: RPA_2b-aaRSs_OBF_like; cl09930
553482003418	generic binding surface II; other site
553482003419	generic binding surface I; other site
553482003420	Maff2 family; Region: Maff2; pfam12750
553482003421	2 transmembrane helices predicted for SEQ0737 by TMHMM2.0 at aa 7-28 and 48-70
553482003422	CDS contains a nonsense mutation (opal) after codon 107. Similar to Clostridium difficile membrane protein UniProt:Q188K5 (EMBL:AM180355 (287 aa) fasta scores: E()=3.2e-96, 96.875% id in 288 aa
553482003423	1 transmembrane helix predicted for SEQ0738 by TMHMM2.0 at aa 64-86
553482003424	3 transmembrane helices predicted for SEQ0739 by TMHMM2.0 at aa 56-78, 114-136 and 151-173
553482003425	1 transmembrane helix predicted for SEQ0740 by TMHMM2.0 at aa 7-24
553482003426	PrgI family protein; Region: PrgI; pfam12666
553482003427	2 transmembrane helices predicted for SEQ0741 by TMHMM2.0 at aa 21-43 and 47-69
553482003428	AAA-like domain; Region: AAA_10; pfam12846
553482003429	Domain of unknown function DUF87; Region: DUF87; pfam01935
553482003430	PS00017 ATP/GTP-binding site motif A (P-loop).
553482003431	Predicted helix-turn-helix motif with score 1329.000, SD 3.71 at aa 653-674, sequence GDREILARKLKISLPQLRYVTN
553482003432	NlpC/P60 family; Region: NLPC_P60; cl17555
553482003433	1 transmembrane helix predicted for SEQ0743 by TMHMM2.0 at aa 360-382
553482003434	Domain of unknown function (DUF4366); Region: DUF4366; pfam14283
553482003435	2 transmembrane helices predicted for SEQ0745 by TMHMM2.0 at aa 12-34 and 452-474
553482003436	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482003437	CDS is truncated by the insertion of the downstream IS element and subsequent deletion events. Similar to N-terminal region of Clostridium difficile DNA topoisomerase UniProt:Q188K6 (EMBL:AM180355 (568 aa) fasta scores: E()=3.4e-86, 89.734% id in 263 aa
553482003438	HMMPfam hit to PF01751, Toprim domain, score 3e-21
553482003439	putative transposase OrfB; Reviewed; Region: PHA02517
553482003440	HTH-like domain; Region: HTH_21; pfam13276
553482003441	Integrase core domain; Region: rve; pfam00665
553482003442	Integrase core domain; Region: rve_2; pfam13333
553482003443	HMMPfam hit to PF00665, Integrase core domain, score 3.6e-35
553482003444	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
553482003445	Helix-turn-helix domain; Region: HTH_28; pfam13518
553482003446	HMMPfam hit to PF01527, Transposase, score 0.00062
553482003447	HMMPfam hit to PF02178, no description, score 0.21
553482003448	Predicted helix-turn-helix motif with score 1140.000, SD 3.07 at aa 19-40, sequence KSIKCLSEKFSIAESDLKYMIR
553482003449	CDS is truncated by the insertion of the upstream IS element and subsequent deletion events. Similar to Clostridium difficile DNA topoisomerase UniProt:Q188K6 (EMBL:AM180355 (568 aa) fasta scores: E()=1.8e-23, 89.655% id in 87 aa
553482003450	Regulators of stationary/sporulation gene expression [Transcription]; Region: AbrB; COG2002
553482003451	SpoVT / AbrB like domain; Region: SpoVT_AbrB; smart00966
553482003452	HMMPfam hit to PF04014, SpoVT / AbrB like domain, score 2.8e-07
553482003453	Predicted transcriptional regulator containing an HTH domain and an uncharacterized domain shared with the mammalian protein Schlafen [Transcription]; Region: COG2865
553482003454	Divergent AAA domain; Region: AAA_4; pfam04326
553482003455	ATP-dependent DNA helicase recG C-terminal; Region: HATPase_c_4; pfam13749
553482003456	HMMPfam hit to PF04326, Divergent AAA domain, score 4e-21
553482003457	Predicted helix-turn-helix motif with score 1981.000, SD 5.93 at aa 434-455, sequence ITRKAIADEAGVSVKTIERAIK
553482003458	PS00017 ATP/GTP-binding site motif A (P-loop).
553482003459	RT_G2_intron: Reverse transcriptases (RTs) with group II intron origin. RT transcribes DNA using RNA as template. Proteins in this subfamily are found in bacterial and mitochondrial group II introns. Their most probable ancestor was a retrotransposable...; Region: RT_G2_intron; cd01651
553482003460	Reverse transcriptase (RNA-dependent DNA polymerase); Region: RVT_1; pfam00078
553482003461	putative active site [active]
553482003462	putative NTP binding site [chemical binding]; other site
553482003463	putative nucleic acid binding site [nucleotide binding]; other site
553482003464	Type II intron maturase; Region: Intron_maturas2; pfam01348
553482003465	HMMPfam hit to PF00078, Reverse transcriptase (RNA-dependent, score 2.2e-73
553482003466	HMMPfam hit to PF01348, Type II intron maturase, score 1.5e-06
553482003467	HMMPfam hit to PF00271, Helicase conserved C-terminal domain, score 0.00019
553482003468	Cro/C1-type HTH DNA-binding domain; Region: HTH_26; pfam13443
553482003469	Predicted helix-turn-helix motif with score 1355.000, SD 3.80 at aa 24-45, sequence MKNSELMEKAEVSRSTFYKMKN
553482003470	type II restriction m6 adenine DNA methyltransferase, Alw26I/Eco31I/Esp3I family; Region: met_A_Alw26; TIGR02987
553482003471	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
553482003472	S-adenosylmethionine binding site [chemical binding]; other site
553482003473	Eco57I restriction-modification methylase; Region: Eco57I; pfam07669
553482003474	HMMPfam hit to PF07669, Eco57I restriction endonuclease, score 6.4e-06
553482003475	PS00092 N-6 Adenine-specific DNA methylases signature.
553482003476	BsuBI/PstI restriction endonuclease C-terminus; Region: BsuBI_PstI_RE; pfam06616
553482003477	HMMPfam hit to PF06616, BsuBI/PstI restriction endonuclease C-t, score 2.7e-89
553482003478	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
553482003479	Helix-turn-helix domain; Region: HTH_28; pfam13518
553482003480	Predicted helix-turn-helix motif with score 1140.000, SD 3.07 at aa 19-40, sequence KSIKCLSEKFSIAESDLKYMIR
553482003481	HMMPfam hit to PF01527, Transposase, score 0.00062
553482003482	HMMPfam hit to PF02178, no description, score 0.21
553482003483	putative transposase OrfB; Reviewed; Region: PHA02517
553482003484	HTH-like domain; Region: HTH_21; pfam13276
553482003485	Integrase core domain; Region: rve; pfam00665
553482003486	Integrase core domain; Region: rve_2; pfam13333
553482003487	HMMPfam hit to PF00665, Integrase core domain, score 1.1e-37
553482003488	SIR2 superfamily of proteins includes silent information regulator 2 (Sir2) enzymes which catalyze NAD+-dependent protein/histone deacetylation, where the acetyl group from the lysine epsilon-amino group is transferred to the ADP-ribose moiety of NAD+; Region: SIR2; cl00195
553482003489	MTH538 TIR-like domain (DUF1863); Region: DUF1863; pfam08937
553482003490	gene remnant. Similar to the C-terminal region of Clostridium difficile 630 mobilization protein UniProt:Q188L0 (EMBL:AM180355 (443 aa) fasta scores: E()=4.6e-32, 87.879% id in 132 aa
553482003491	Predicted ATPase (AAA+ superfamily) [General function prediction only]; Region: COG1373
553482003492	AAA domain; Region: AAA_14; pfam13173
553482003493	PS00017 ATP/GTP-binding site motif A (P-loop).
553482003494	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
553482003495	catalytic core [active]
553482003496	HMMPfam hit to PF00300, Phosphoglycerate mutase family, score 2.5e-39
553482003497	hypothetical protein; Provisional; Region: PRK11770
553482003498	Domain of unknown function (DUF307); Region: DUF307; pfam03733
553482003499	Domain of unknown function (DUF307); Region: DUF307; pfam03733
553482003500	HMMPfam hit to PF03733, Domain of unknown function (DUF307), score 3.6e-21
553482003501	3 transmembrane helices predicted for SEQ0766 by TMHMM2.0 at aa 15-37, 50-72 and 77-99
553482003502	HMMPfam hit to PF03733, Domain of unknown function (DUF307), score 1.9e-13
553482003503	This CD includes cysteinyl-tRNA(Pro) deacylases from Haemophilus influenzae and Escherichia coli and other related bacterial proteins. These trans-acting, single-domain proteins are homologs of ProX and also the cis-acting prolyl-tRNA synthetase (ProRS)...; Region: YbaK_deacylase; cd00002
553482003504	putative deacylase active site [active]
553482003505	HMMPfam hit to PF04073, YbaK / prolyl-tRNA synthetases associated do, score 1.2e-54
553482003506	Thiamine transporter protein (Thia_YuaJ); Region: Thia_YuaJ; cl17491
553482003507	5 transmembrane helices predicted for SEQ0768 by TMHMM2.0 at aa 13-35, 50-69, 74-96, 111-133 and 154-176
553482003508	Lyzozyme M1 (1,4-beta-N-acetylmuramidase) [Cell envelope biogenesis, outer membrane]; Region: Acm; COG3757
553482003509	PlyB is a bacteriophage endolysin that displays potent lytic activity toward Bacillus anthracis.  PlyB has an N-terminal glycosyl hydrolase family 25 (GH25) catalytic domain and a C-terminal bacterial SH3-like domain, SH3b.  Both domains are required for...; Region: GH25_PlyB-like; cd06523
553482003510	active site
553482003511	HMMPfam hit to PF01183, Glycosyl hydrolases family, score 2e-06
553482003512	1 transmembrane helix predicted for SEQ0769 by TMHMM2.0 at aa 7-24
553482003513	5 transmembrane helices predicted for SEQ0770 by TMHMM2.0 at aa 10-29, 36-58, 68-90, 103-125 and 135-157
553482003514	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482003515	10 transmembrane helices predicted for SEQ0771 by TMHMM2.0 at aa 21-43, 48-70, 77-99, 103-121, 165-187, 242-264, 285-307, 311-328, 341-363 and 368-390
553482003516	Glutathione (GSH) peroxidase family; tetrameric selenoenzymes that catalyze the reduction of a variety of hydroperoxides including lipid peroxidases, using GSH as a specific electron donor substrate. GSH peroxidase contains one selenocysteine residue per...; Region: GSH_Peroxidase; cd00340
553482003517	catalytic residues [active]
553482003518	dimer interface [polypeptide binding]; other site
553482003519	HMMPfam hit to PF00255, Glutathione peroxidase, score 3e-50
553482003520	PS00763 Glutathione peroxidases signature 2.
553482003521	PS00460 Glutathione peroxidases selenocysteine active site.
553482003522	CDS contains a frameshift after codon 126. Frameshift occurs at a poly A octamer
553482003523	HMMPfam hit to PF01432, Peptidase family M3, score 1.2e-33
553482003524	PS00142 Neutral zinc metallopeptidases, zinc-binding region signature.
553482003525	phosphoenolpyruvate carboxylase; Reviewed; Region: PRK00009
553482003526	Phosphoenolpyruvate carboxylase [Energy production and conversion]; Region: Ppc; COG2352
553482003527	HMMPfam hit to PF00311, Phosphoenolpyruvate carboxylase, score 1.6e-86
553482003528	PS00781 Phosphoenolpyruvate carboxylase active site 1.
553482003529	PS00393 Phosphoenolpyruvate carboxylase active site 2.
553482003530	Bacterial cell division membrane protein [Cell division and chromosome partitioning]; Region: FtsW; COG0772
553482003531	HMMPfam hit to PF01098, Cell cycle protein, score 2.4e-91
553482003532	8 transmembrane helices predicted for SEQ0777 by TMHMM2.0 at aa 13-35, 50-72, 77-99, 179-198, 203-225, 302-324, 337-359 and 364-386
553482003533	putative transposase OrfB; Reviewed; Region: PHA02517
553482003534	HTH-like domain; Region: HTH_21; pfam13276
553482003535	Integrase core domain; Region: rve; pfam00665
553482003536	Integrase core domain; Region: rve_2; pfam13333
553482003537	HMMPfam hit to PF00665, Integrase core domain, score 1.8e-39
553482003538	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
553482003539	Helix-turn-helix domain; Region: HTH_28; pfam13518
553482003540	HMMPfam hit to PF01527, Transposase, score 0.0014
553482003541	HMMPfam hit to PF02178, no description, score 0.21
553482003542	Predicted helix-turn-helix motif with score 1140.000, SD 3.07 at aa 19-40, sequence KSIKCLSEKFSIAESDLKYMIR
553482003543	gene remnant. Similar to the C-terminal region of Streptococcus thermophilus peptide-2 ABC exporter family, ATP binding/membrane-spannin protein UniProt:Q5M3B9 (EMBL:CP000023 (523 aa) fasta scores: E()=9.4e-18, 42.246% id in 187 aa
553482003544	HMMPfam hit to PF00005, ABC transporter, score 6.1e-35
553482003545	PS00017 ATP/GTP-binding site motif A (P-loop).
553482003546	PS00211 ABC transporters family signature.
553482003547	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
553482003548	ATP-binding cassette domain of multidrug resistance protein-like transporters; Region: ABCC_MRP_Like; cd03228
553482003549	Walker A/P-loop; other site
553482003550	ATP binding site [chemical binding]; other site
553482003551	Q-loop/lid; other site
553482003552	ABC transporter signature motif; other site
553482003553	Walker B; other site
553482003554	D-loop; other site
553482003555	H-loop/switch region; other site
553482003556	5 transmembrane helices predicted for SEQ0781 by TMHMM2.0 at aa 7-29, 52-74, 115-137, 147-166 and 231-253
553482003557	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482003558	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482003559	HMMPfam hit to PF00005, ABC transporter, score 3.6e-32
553482003560	PS00017 ATP/GTP-binding site motif A (P-loop).
553482003561	PS00211 ABC transporters family signature.
553482003562	peptide chain release factor 2; Validated; Region: prfB; PRK00578
553482003563	PCRF domain; Region: PCRF; pfam03462
553482003564	RF-1 domain; Region: RF-1; pfam00472
553482003565	HMMPfam hit to PF03462, PCRF domain, score 2.4e-58
553482003566	HMMPfam hit to PF00472, Peptidyl-tRNA hydrolase domain, score 1.3e-64
553482003567	Predicted ATPase involved in cell division [Cell division and chromosome partitioning]; Region: FtsE; COG2884
553482003568	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
553482003569	Walker A/P-loop; other site
553482003570	ATP binding site [chemical binding]; other site
553482003571	Q-loop/lid; other site
553482003572	ABC transporter signature motif; other site
553482003573	Walker B; other site
553482003574	D-loop; other site
553482003575	H-loop/switch region; other site
553482003576	HMMPfam hit to PF00005, ABC transporter, score 3.4e-61
553482003577	PS00017 ATP/GTP-binding site motif A (P-loop).
553482003578	PS00211 ABC transporters family signature.
553482003579	Cell division protein [Cell division and chromosome partitioning]; Region: FtsX; COG2177
553482003580	cell division ABC transporter subunit FtsX; Provisional; Region: ftsX; PRK11026
553482003581	4 transmembrane helices predicted for SEQ0784 by TMHMM2.0 at aa 23-45, 183-205, 235-257 and 282-304
553482003582	HMMPfam hit to PF02687, Predicted permease, score 3.5e-34
553482003583	Zn-dependent hydrolases, including glyoxylases [General function prediction only]; Region: GloB; COG0491
553482003584	bifunctional ATP-dependent DNA helicase/DNA polymerase III subunit epsilon; Validated; Region: PRK07246
553482003585	DEDDh 3'-5' exonuclease domain family; Region: DEDDh; cd06127
553482003586	active site
553482003587	catalytic site [active]
553482003588	substrate binding site [chemical binding]; other site
553482003589	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cl17251
553482003590	ATP binding site [chemical binding]; other site
553482003591	Helicase C-terminal domain; Region: Helicase_C_2; pfam13307
553482003592	HMMPfam hit to PF00929, Exonuclease, score 2.8e-35
553482003593	PS00017 ATP/GTP-binding site motif A (P-loop).
553482003594	prophage phiSeq2
553482003595	DNA breaking-rejoining enzymes, intergrase/recombinases, C-terminal catalytic domain. The tyrosine recombinase/integrase family share the same catalytic domain containing six conserved active site residues. The best-studied members of this diverse family...; Region: INT_REC_C; cd01182
553482003596	active site
553482003597	catalytic residues [active]
553482003598	DNA binding site [nucleotide binding]
553482003599	Int/Topo IB signature motif; other site
553482003600	HMMPfam hit to PF00589, Phage integrase family, score 1e-06
553482003601	Poxvirus P35 protein; Region: Pox_P35; pfam03213
553482003602	2 transmembrane helices predicted for SEQ0788 by TMHMM2.0 at aa 36-58 and 62-84
553482003603	Domain of unknown function (DUF955); Region: DUF955; pfam06114
553482003604	HMMPfam hit to PF06114, Domain of unknown function (DUF955), score 1.1e-20
553482003605	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
553482003606	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
553482003607	non-specific DNA binding site [nucleotide binding]; other site
553482003608	salt bridge; other site
553482003609	sequence-specific DNA binding site [nucleotide binding]; other site
553482003610	HMMPfam hit to PF01381, Helix-turn-helix, score 9.5e-11
553482003611	Predicted helix-turn-helix motif with score 1486.000, SD 4.25 at aa 17-38, sequence ISIAKLEENLGLSKNAIYAIKR
553482003612	putative transposase OrfB; Reviewed; Region: PHA02517
553482003613	HTH-like domain; Region: HTH_21; pfam13276
553482003614	Integrase core domain; Region: rve; pfam00665
553482003615	Integrase core domain; Region: rve_2; pfam13333
553482003616	HMMPfam hit to PF00665, Integrase core domain, score 1.1e-37
553482003617	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
553482003618	Helix-turn-helix domain; Region: HTH_28; pfam13518
553482003619	HMMPfam hit to PF01527, Transposase, score 0.00062
553482003620	HMMPfam hit to PF02178, no description, score 0.21
553482003621	Predicted helix-turn-helix motif with score 1140.000, SD 3.07 at aa 19-40, sequence KSIKCLSEKFSIAESDLKYMIR
553482003622	Prophage CP4-57 regulatory protein (AlpA); Region: Phage_AlpA; cl17523
553482003623	HMMPfam hit to PF05930, Prophage CP4-57 regulatory protein (AlpA), score 0.015
553482003624	Predicted helix-turn-helix motif with score 1749.000, SD 5.14 at aa 36-57, sequence LTREKVADRLNMSPATFDKYYR
553482003625	Siphovirus Gp157; Region: Sipho_Gp157; pfam05565
553482003626	HMMPfam hit to PF05565, Siphovirus Gp157, score 1.3e-48
553482003627	DEAD-like helicases superfamily; Region: DEXDc; smart00487
553482003628	Type III restriction enzyme, res subunit; Region: ResIII; pfam04851
553482003629	HMMPfam hit to PF04851, Type III restriction enzyme, res subunit, score 4.3e-06
553482003630	PS00017 ATP/GTP-binding site motif A (P-loop).
553482003631	ERF superfamily; Region: ERF; pfam04404
553482003632	Single-stranded DNA-binding protein [DNA replication, recombination, and repair]; Region: Ssb; COG0629
553482003633	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
553482003634	dimer interface [polypeptide binding]; other site
553482003635	ssDNA binding site [nucleotide binding]; other site
553482003636	tetramer (dimer of dimers) interface [polypeptide binding]; other site
553482003637	HMMPfam hit to PF00436, Single-strand binding protein family, score 9.7e-32
553482003638	Prim_Pol: Primase-polymerase (primpol) domain of the type found in bifunctional replicases from archaeal plasmids, including ORF904 protein of the crenarchaeal plasmid pRN1 from Sulfolobus islandicus (pRN1 primpol). These primpol domains belong to the...; Region: Prim_Pol; cd04859
553482003639	polymerase nucleotide-binding site; other site
553482003640	DNA-binding residues [nucleotide binding]; DNA binding site
553482003641	nucleotide binding site [chemical binding]; other site
553482003642	primase nucleotide-binding site [nucleotide binding]; other site
553482003643	Primase C terminal 1 (PriCT-1); Region: PriCT_1; pfam08708
553482003644	Virulence-associated protein E; Region: VirE; pfam05272
553482003645	HMMPfam hit to PF05272, Virulence-associated protein E, score 1.3e-77
553482003646	PS00017 ATP/GTP-binding site motif A (P-loop).
553482003647	1 transmembrane helix predicted for SEQ0806 by TMHMM2.0 at aa 7-26
553482003648	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482003649	DNA modification methylase [DNA replication, recombination, and repair]; Region: COG0863
553482003650	DNA methylase; Region: N6_N4_Mtase; pfam01555
553482003651	HMMPfam hit to PF01555, DNA methylase, score 2e-51
553482003652	PS00092 N-6 Adenine-specific DNA methylases signature.
553482003653	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482003654	CDS contains a frameshift after codon 263. Similar to Streptococcus pyogenes serotype M6 DNA-cytosine methyltransferase UniProt:Q5XBD5 (EMBL:CP000003 (422 aa) fasta scores: E()=2.1e-31, 31.860% id in 430 aa
553482003655	HMMPfam hit to PF00145, C-5 cytosine-specific DNA methylase, score 4.3e-54
553482003656	PS00094 C-5 cytosine-specific DNA methylases active site.
553482003657	PS00095 C-5 cytosine-specific DNA methylases C-terminal signature.
553482003658	Protein of unknown function (DUF1642); Region: DUF1642; pfam07852
553482003659	HMMPfam hit to PF07852, Protein of unknown function (DUF1642), score 8.8e-25
553482003660	3 transmembrane helices predicted for SEQ0811 by TMHMM2.0 at aa 24-46, 56-75 and 88-107
553482003661	phage transcriptional regulator, ArpU family; Region: phage_arpU; TIGR01637
553482003662	Uncharacterized protein family (UPF0150); Region: UPF0150; pfam03681
553482003663	HMMPfam hit to PF03681, Uncharacterised protein family (UPF0150), score 1.7e-18
553482003664	YcfA-like protein; Region: YcfA; pfam07927
553482003665	HMMPfam hit to PF07927, YcfA-like protein, score 1.2e-20
553482003666	HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and...; Region: HNHc; cd00085
553482003667	active site
553482003668	HMMPfam hit to PF01844, HNH endonuclease, score 2.4e-06
553482003669	Phage terminase, small subunit; Region: Terminase_4; pfam05119
553482003670	HMMPfam hit to PF05119, Phage terminase, small subunit, score 4.7e-21
553482003671	Phage Terminase; Region: Terminase_1; pfam03354
553482003672	HMMPfam hit to PF03354, Phage Terminase, score 1.2e-121
553482003673	2 transmembrane helices predicted for SEQ0821 by TMHMM2.0 at aa 5-27 and 32-51
553482003674	phage portal protein, HK97 family; Region: portal_HK97; TIGR01537
553482003675	Phage-related protein [Function unknown]; Region: COG4695; cl01923
553482003676	HMMPfam hit to PF04860, Phage portal protein, score 5.1e-35
553482003677	Caseinolytic protease (ClpP) is an ATP-dependent, highly conserved serine protease; Region: S14_ClpP_1; cd07016
553482003678	oligomer interface [polypeptide binding]; other site
553482003679	active site residues [active]
553482003680	HMMPfam hit to PF00574, Clp protease, score 1.7e-24
553482003681	phage major capsid protein, HK97 family; Region: major_cap_HK97; TIGR01554
553482003682	Phage capsid family; Region: Phage_capsid; pfam05065
553482003683	HMMPfam hit to PF05065, Phage capsid family, score 2.4e-111
553482003684	PS00017 ATP/GTP-binding site motif A (P-loop).
553482003685	Head-Tail Connector Protein gp6 of Bacteriophage HK97 and similar proteins; Region: gp6; cd08054
553482003686	oligomerization interface [polypeptide binding]; other site
553482003687	Phage head-tail joining protein; Region: Phage_H_T_join; pfam05521
553482003688	phage protein, HK97 gp10 family; Region: phge_HK97_gp10; TIGR01725
553482003689	phage major tail protein, phi13 family; Region: maj_tail_phi13; TIGR01603
553482003690	phage tail tape measure protein, TP901 family, core region; Region: tape_meas_TP901; TIGR01760
553482003691	PS00038 Myc-type, 'helix-loop-helix' dimerization domain signature.
553482003692	Predicted helix-turn-helix motif with score 1118.000, SD 2.99 at aa 685-706, sequence KKDLKLAEKLGLSQETIEEIRR
553482003693	Phage-related protein [Function unknown]; Region: COG4722
553482003694	Phage tail protein; Region: Sipho_tail; pfam05709
553482003695	Phage-related protein [Function unknown]; Region: PblB; COG4926
553482003696	Prophage endopeptidase tail; Region: Prophage_tail; cl12123
553482003697	Collagen triple helix repeat (20 copies); Region: Collagen; pfam01391
553482003698	HMMPfam hit to PF01391, Collagen triple helix repeat (20 copies), score 6.5e-06
553482003699	gp58-like protein; Region: Gp58; pfam07902
553482003700	HMMPfam hit to PF07902, gp58-like protein, score 0
553482003701	Protein of unknown function (DUF1617); Region: DUF1617; pfam07761
553482003702	HMMPfam hit to PF07761, Protein of unknown function (DUF1617), score 3e-95
553482003703	1 transmembrane helix predicted for SEQ0842 by TMHMM2.0 at aa 4-26
553482003704	1 transmembrane helix predicted for SEQ0843 by TMHMM2.0 at aa 21-43
553482003705	1 transmembrane helix predicted for SEQ0844 by TMHMM2.0 at aa 7-29
553482003706	Muramidase (flagellum-specific) [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FlgJ; COG1705
553482003707	CHAP domain; Region: CHAP; pfam05257
553482003708	Bacterial SH3 domain; Region: SH3_5; pfam08460
553482003709	HMMPfam hit to PF01832, Mannosyl-glycoprotein endo-beta-N-ace, score 6.3e-18
553482003710	PS00639 Eukaryotic thiol (cysteine) proteases histidine active site.
553482003711	HMMPfam hit to PF05257, CHAP domain, score 1.2e-32
553482003712	HMMPfam hit to PF08460, Bacterial SH3 domain, score 2.3e-07
553482003713	Protein of unknown function (DUF4065); Region: DUF4065; pfam13274
553482003714	3 transmembrane helices predicted for SEQ0847 by TMHMM2.0 at aa 167-189, 204-226 and 258-277
553482003715	PLA2_like: Phospholipase A2, a super-family of secretory and cytosolic enzymes; the latter are either Ca dependent or Ca independent. PLA2 cleaves the sn-2 position of the glycerol backbone of phospholipids (PC or phosphatidylethanolamine), usually in a...; Region: PLA2_like; cl05417
553482003716	primary metal binding site; other site
553482003717	catalytic residues [active]
553482003718	1 transmembrane helix predicted for SEQ0849 by TMHMM2.0 at aa 5-27
553482003719	3 transmembrane helices predicted for SEQ0850 by TMHMM2.0 at aa 12-29, 39-61 and 68-90
553482003720	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG5353
553482003721	aspartate aminotransferase; Provisional; Region: PRK05764
553482003722	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
553482003723	pyridoxal 5'-phosphate binding site [chemical binding]; other site
553482003724	homodimer interface [polypeptide binding]; other site
553482003725	catalytic residue [active]
553482003726	HMMPfam hit to PF00155, Aminotransferase class I and II, score 4.7e-94
553482003727	PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site.
553482003728	asparaginyl-tRNA synthetase; Validated; Region: asnC; PRK03932
553482003729	AsnRS_cyto_like_N: N-terminal, anticodon recognition domain of the type found in human and Saccharomyces cerevisiae cytoplasmic asparaginyl-tRNA synthetase (AsnRS), in Brugia malayai AsnRs and, in various putative bacterial AsnRSs.  This domain is a...; Region: AsnRS_cyto_like_N; cd04323
553482003730	putative dimer interface [polypeptide binding]; other site
553482003731	putative anticodon binding site; other site
553482003732	Asx tRNA synthetase (AspRS/AsnRS) class II core domain.  Assignment to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure and the presence of three characteristic sequence motifs in the core domain. This family includes AsnRS as well as...; Region: AsxRS_core; cd00776
553482003733	homodimer interface [polypeptide binding]; other site
553482003734	motif 1; other site
553482003735	motif 2; other site
553482003736	active site
553482003737	motif 3; other site
553482003738	HMMPfam hit to PF01336, OB-fold nucleic acid binding domain, score 1.5e-17
553482003739	HMMPfam hit to PF00152, tRNA synthetases class II (D, K and N), score 1.5e-96
553482003740	PS00179 Aminoacyl-transfer RNA synthetases class-II signature 1.
553482003741	PS00339 Aminoacyl-transfer RNA synthetases class-II signature 2.
553482003742	Collagen triple helix repeat (20 copies); Region: Collagen; pfam01391
553482003743	Collagen triple helix repeat (20 copies); Region: Collagen; pfam01391
553482003744	Collagen triple helix repeat (20 copies); Region: Collagen; pfam01391
553482003745	LPXTG-motif cell wall anchor domain; Region: LPXTG_anchor; TIGR01167
553482003746	HMMPfam hit to PF01391, Collagen triple helix repeat (20 copi, score 1.4e-11
553482003747	HMMPfam hit to PF01391, Collagen triple helix repeat (20 copi, score 1.6e-14
553482003748	HMMPfam hit to PF01391, Collagen triple helix repeat (20 copi, score 1e-13
553482003749	HMMPfam hit to PF00746, Gram positive anchor, score 1.1e-06
553482003750	PS00343 Gram-positive cocci surface proteins 'anchoring' hexapeptide.
553482003751	1 transmembrane helix predicted for SEQ0855 by TMHMM2.0 at aa 342-359
553482003752	glmZ(sRNA)-inactivating NTPase; Provisional; Region: PRK05416
553482003753	AAA domain; Region: AAA_33; pfam13671
553482003754	HMMPfam hit to PF03668, P-loop ATPase protein family, score 9.1e-126
553482003755	PS00017 ATP/GTP-binding site motif A (P-loop).
553482003756	PS00017 ATP/GTP-binding site motif A (P-loop).
553482003757	conserved hypothetical protein, cofD-related; Region: CofD_related; TIGR01826
553482003758	Family of CofD-like proteins and proteins related to YvcK; Region: CofD_YvcK; cd07044
553482003759	dimer interface [polypeptide binding]; other site
553482003760	phosphate binding site [ion binding]; other site
553482003761	HMMPfam hit to PF01933, Uncharacterised protein family UPF0052, score 4.9e-146
553482003762	PS01036 Heat shock hsp70 proteins family signature 3.
553482003763	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1481
553482003764	Sporulation Regulator WhiA N terminal; Region: WhiA_N; pfam10298
553482003765	HMMPfam hit to PF02650, Uncharacterized BCR, COG1481, score 1.5e-64
553482003766	Peptidase family C69; Region: Peptidase_C69; pfam03577
553482003767	HMMPfam hit to PF03577, Peptidase family C69, score 1.1e-273
553482003768	ABC-type metal ion transport system, periplasmic component/surface adhesin [Inorganic ion transport and metabolism]; Region: LraI; COG0803
553482003769	Metal binding protein AcdA.  These proteins have been shown to function in the ABC uptake of Zn2+ and Mn2+ and in competence for genetic transformation and adhesion. The AcdA proteins belong to the TroA superfamily of helical backbone metal receptor...; Region: AdcA; cd01017
553482003770	metal binding site [ion binding]; metal-binding site
553482003771	YodA lipocalin-like domain; Region: YodA; pfam09223
553482003772	HMMPfam hit to PF01297, Periplasmic solute binding protein family, score 3.4e-82
553482003773	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
553482003774	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
553482003775	DNA-binding site [nucleotide binding]; DNA binding site
553482003776	UTRA domain; Region: UTRA; pfam07702
553482003777	HMMPfam hit to PF00392, Bacterial regulatory proteins, gntR family, score 3.3e-14
553482003778	PS00043 Bacterial regulatory proteins, gntR family signature.
553482003779	Predicted helix-turn-helix motif with score 1586.000, SD 4.59 at aa 30-51, sequence LSERELSDLFGVSRITIRLALK
553482003780	HMMPfam hit to PF07702, UTRA domain, score 1.5e-43
553482003781	putative sugar isomerase, AgaS family; Region: agaS_fam; TIGR02815
553482003782	SIS (Sugar ISomerase) domain repeat 1 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_1; cd05008
553482003783	dimer interface [polypeptide binding]; other site
553482003784	active site
553482003785	AgaS-like protein. AgaS contains a SIS (Sugar ISomerase) domain which is found in many phosphosugar isomerases and phosphosugar binding proteins. AgaS is a putative isomerase in Escherichia coli. It is similar to the glucosamine-6-phosphate synthases; Region: SIS_AgaS_like; cd05010
553482003786	putative active site [active]
553482003787	HMMPfam hit to PF01380, SIS domain, score 5e-06
553482003788	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482003789	HMMPfam hit to PF01380, SIS domain, score 0.022
553482003790	tagatose 1,6-diphosphate aldolase; Reviewed; Region: PRK04161
553482003791	HMMPfam hit to PF01791, DeoC/LacD family aldolase, score 3e-103
553482003792	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
553482003793	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
553482003794	DNA-binding site [nucleotide binding]; DNA binding site
553482003795	The UbiC transcription regulator-associated (UTRA) domain is a conserved ligand-binding domain; Region: UTRA; smart00866
553482003796	HMMPfam hit to PF07702, UTRA domain, score 6.6e-05
553482003797	HMMPfam hit to PF00392, Bacterial regulatory proteins, gntR family, score 6.9e-13
553482003798	Predicted helix-turn-helix motif with score 1112.000, SD 2.97 at aa 31-52, sequence YTEAELIKRFHVSSITIIRALK
553482003799	HMMPfam hit to PF01301, Glycosyl hydrolases family, score 1.2e-170
553482003800	HMMPfam hit to PF02449, Beta-galactosidase, score 0.00023
553482003801	putative transposase OrfB; Reviewed; Region: PHA02517
553482003802	HTH-like domain; Region: HTH_21; pfam13276
553482003803	Integrase core domain; Region: rve; pfam00665
553482003804	Integrase core domain; Region: rve_2; pfam13333
553482003805	HMMPfam hit to PF00665, Integrase core domain, score 1.1e-37
553482003806	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
553482003807	Helix-turn-helix domain; Region: HTH_28; pfam13518
553482003808	HMMPfam hit to PF01527, Transposase, score 0.00062
553482003809	HMMPfam hit to PF02178, no description, score 0.21
553482003810	Predicted helix-turn-helix motif with score 1140.000, SD 3.07 at aa 19-40, sequence KSIKCLSEKFSIAESDLKYMIR
553482003811	PTS_IIB, PTS system, Mannose/sorbose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_man; cd00001
553482003812	active site
553482003813	phosphorylation site [posttranslational modification]
553482003814	HMMPfam hit to PF03830, PTS system sorbose subfamily IIB componen, score 1.3e-66
553482003815	CDS contains a nonsense mutation (ochre) after codon 139. Similar to Streptococcus pneumoniae R6 Phosphotransferase system sugar-specific EIIC component PTS-EIIC UniProt:Q8DRL2 (EMBL:AE008390 (301 aa) fasta scores: E()=3.9e-61, 69.435% id in 301 aa
553482003816	HMMPfam hit to PF03609, PTS system sorbose-specific iic component, score 1.9e-17
553482003817	6 transmembrane helices predicted for SEQ0871 by TMHMM2.0 at aa 21-43, 47-69, 143-165, 175-197, 204-226 and 241-263
553482003818	PTS system mannose/fructose/sorbose family IID component; Region: EIID-AGA; pfam03613
553482003819	HMMPfam hit to PF03613, PTS system mannose/fructose/sorbose family I, score 1.4e-103
553482003820	5 transmembrane helices predicted for SEQ0872 by TMHMM2.0 at aa 115-132, 136-158, 179-201, 225-244 and 253-270
553482003821	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cd00006
553482003822	active pocket/dimerization site; other site
553482003823	active site
553482003824	phosphorylation site [posttranslational modification]
553482003825	HMMPfam hit to PF03610, PTS system fructose IIA component, score 1.1e-26
553482003826	50S ribosomal protein L31 type B; Reviewed; Region: rpmE2; PRK01678
553482003827	HMMPfam hit to PF01197, Ribosomal protein L31, score 2.4e-21
553482003828	PS01143 Ribosomal protein L31 signature.
553482003829	Exopolyphosphatase-related proteins [General function prediction only]; Region: COG0618
553482003830	DHH family; Region: DHH; pfam01368
553482003831	DHHA1 domain; Region: DHHA1; pfam02272
553482003832	HMMPfam hit to PF02272, DHHA1 domain, score 3.6e-06
553482003833	HMMPfam hit to PF01368, DHH family, score 5.6e-43
553482003834	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
553482003835	Coenzyme A binding pocket [chemical binding]; other site
553482003836	HMMPfam hit to PF00583, Acetyltransferase (GNAT) family, score 6.2e-09
553482003837	Adenosine deaminase [Nucleotide transport and metabolism]; Region: Add; COG1816
553482003838	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
553482003839	active site
553482003840	HMMPfam hit to PF00962, Adenosine/AMP deaminase, score 2.6e-54
553482003841	HMMPfam hit to PF02828, L27 domain, score 0.035
553482003842	flavodoxin; Validated; Region: PRK07308
553482003843	HMMPfam hit to PF00258, Flavodoxin, score 1.6e-28
553482003844	HMMPfam hit to PF07972, NrdI Flavodoxin like, score 0.00041
553482003845	PS00201 Flavodoxin signature.
553482003846	hypothetical protein; Provisional; Region: PRK07248
553482003847	HMMPfam hit to PF01817, Chorismate mutase type II, score 9.7e-24
553482003848	CLC voltage-gated chloride channel. The ClC chloride channels catalyse the selective flow of Cl- ions across cell membranes, thereby regulating electrical excitation in skeletal muscle and the flow of salt and water across epithelial barriers. This...; Region: Voltage_gated_ClC; cl02915
553482003849	Chloride channel protein EriC [Inorganic ion transport and metabolism]; Region: EriC; COG0038
553482003850	Cl- selectivity filter; other site
553482003851	Cl- binding residues [ion binding]; other site
553482003852	pore gating glutamate residue; other site
553482003853	dimer interface [polypeptide binding]; other site
553482003854	10 transmembrane helices predicted for SEQ0880 by TMHMM2.0 at aa 17-36, 51-73, 94-111, 146-168, 173-195, 215-237, 256-278, 320-339, 346-368 and 372-391
553482003855	HMMPfam hit to PF00654, Voltage gated chloride channel, score 5e-11
553482003856	50S ribosomal protein L19; Provisional; Region: rplS; PRK05338
553482003857	PS01015 Ribosomal protein L19 signature.
553482003858	DNA/RNA non-specific endonuclease; Region: Endonuclease_NS; smart00892
553482003859	DNA/RNA non-specific endonuclease; Region: Endonuclea_NS_2; cl17626
553482003860	HMMPfam hit to PF01223, DNA/RNA non-specific endonuclease, score 2.1e-05
553482003861	1 transmembrane helix predicted for SEQ0882 by TMHMM2.0 at aa 25-42
553482003862	Predicted helix-turn-helix motif with score 975.000, SD 2.51 at aa 4-25, sequence LTRKQKKEGIDMSKSRRRNWKS
553482003863	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
553482003864	non-specific DNA binding site [nucleotide binding]; other site
553482003865	salt bridge; other site
553482003866	sequence-specific DNA binding site [nucleotide binding]; other site
553482003867	HMMPfam hit to PF01381, Helix-turn-helix, score 7e-15
553482003868	Predicted helix-turn-helix motif with score 1899.000, SD 5.65 at aa 18-39, sequence INQTQMAALAGVSRQTISLIER
553482003869	Protein of unknown function (DUF3169); Region: DUF3169; pfam11368
553482003870	6 transmembrane helices predicted for SEQ0884 by TMHMM2.0 at aa 20-42, 62-81, 108-130, 140-162, 204-226 and 230-247
553482003871	Putative ClC chloride channel.  Clc proteins are putative halogen ion (Cl-, Br- and I-) transporters found in eubacteria. They belong to the ClC superfamily of halogen ion channels, which share a unique double-barreled architecture and voltage-dependent...; Region: ClC_like; cd01033
553482003872	putative ion selectivity filter; other site
553482003873	Chloride channel protein EriC [Inorganic ion transport and metabolism]; Region: EriC; COG0038
553482003874	putative pore gating glutamate residue; other site
553482003875	11 transmembrane helices predicted for SEQ0885 by TMHMM2.0 at aa 7-29, 33-55, 62-79, 157-179, 186-208, 223-245, 258-280, 295-317, 324-346, 356-378 and 385-407
553482003876	HMMPfam hit to PF00654, Voltage gated chloride channel, score 2.3e-07
553482003877	ribonucleotide-diphosphate reductase subunit beta; Provisional; Region: nrdF2; PRK13966
553482003878	Ribonucleotide Reductase, R2/beta subunit, ferritin-like diiron-binding domain; Region: RNRR2; cd01049
553482003879	dimer interface [polypeptide binding]; other site
553482003880	putative radical transfer pathway; other site
553482003881	diiron center [ion binding]; other site
553482003882	tyrosyl radical; other site
553482003883	HMMPfam hit to PF00268, Ribonucleotide reductase, small chain, score 1.7e-61
553482003884	ribonucleotide-diphosphate reductase subunit alpha; Validated; Region: PRK07306
553482003885	Ribonucleotide reductase N-terminal; Region: RNR_N; pfam08343
553482003886	Class I ribonucleotide reductase; Region: RNR_I; cd01679
553482003887	active site
553482003888	dimer interface [polypeptide binding]; other site
553482003889	catalytic residues [active]
553482003890	effector binding site; other site
553482003891	R2 peptide binding site; other site
553482003892	HMMPfam hit to PF02867, Ribonucleotide reductase, barrel doma, score 5.3e-130
553482003893	PS00089 Ribonucleotide reductase large subunit signature.
553482003894	HMMPfam hit to PF00317, Ribonucleotide reductase, all-alpha d, score 1.2e-26
553482003895	HMMPfam hit to PF08343, Ribonucleotide reductase N-terminal, score 2.2e-42
553482003896	NrdH-redoxin (NrdH) family; NrdH is a small monomeric protein with a conserved redox active CXXC motif within a TRX fold, characterized by a glutaredoxin (GRX)-like sequence and TRX-like activity profile. In vitro, it displays protein disulfide reductase...; Region: NrdH; cd02976
553482003897	catalytic residues [active]
553482003898	HMMPfam hit to PF00462, Glutaredoxin, score 9.6e-16
553482003899	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
553482003900	dimerization domain swap beta strand [polypeptide binding]; other site
553482003901	regulatory protein interface [polypeptide binding]; other site
553482003902	active site
553482003903	regulatory phosphorylation site [posttranslational modification]; other site
553482003904	HMMPfam hit to PF00381, PTS HPr component phosphorylation site, score 5.5e-52
553482003905	PS00369 PTS HPR component histidine phosphorylation site signature.
553482003906	PS00589 PTS HPR component serine phosphorylation site signature.
553482003907	Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) [Carbohydrate transport and metabolism]; Region: PtsA; COG1080
553482003908	PEP-utilising enzyme, N-terminal; Region: PEP-utilisers_N; pfam05524
553482003909	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
553482003910	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
553482003911	HMMPfam hit to PF05524, PEP-utilising enzyme, N-terminal, score 1.4e-59
553482003912	HMMPfam hit to PF00391, PEP-utilising enzyme, mobile domain, score 1.7e-40
553482003913	PS00370 PEP-utilizing enzymes phosphorylation site signature.
553482003914	HMMPfam hit to PF02896, PEP-utilising enzyme, TIM barrel doma, score 1.1e-193
553482003915	PS00742 PEP-utilizing enzymes signature 2.
553482003916	NADP+-dependent non-phosphorylating glyceraldehyde 3-phosphate dehydrogenase and ALDH family 11; Region: ALDH_F11_NP-GAPDH; cd07082
553482003917	NADP-dependent glyceraldehyde-3-phosphate dehydrogenase; Provisional; Region: PLN00412
553482003918	tetrameric interface [polypeptide binding]; other site
553482003919	activator binding site; other site
553482003920	NADP binding site [chemical binding]; other site
553482003921	substrate binding site [chemical binding]; other site
553482003922	catalytic residues [active]
553482003923	HMMPfam hit to PF00171, Aldehyde dehydrogenase family, score 7.9e-180
553482003924	PS00070 Aldehyde dehydrogenases cysteine active site.
553482003925	Bacterial cell division membrane protein [Cell division and chromosome partitioning]; Region: FtsW; COG0772
553482003926	10 transmembrane helices predicted for SEQ0892 by TMHMM2.0 at aa 12-34, 49-71, 78-100, 115-137, 150-169, 173-192, 194-216, 288-310, 323-345 and 360-382
553482003927	HMMPfam hit to PF01098, Cell cycle protein, score 9.2e-70
553482003928	haloacid dehalogenase superfamily, subfamily IA, variant 1 with third motif having Dx(3-4)D or Dx(3-4)E; Region: HAD-SF-IA-v1; TIGR01549
553482003929	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
553482003930	motif II; other site
553482003931	HMMPfam hit to PF00702, haloacid dehalogenase-like hydrolase, score 2.5e-14
553482003932	DNA gyrase subunit B; Validated; Region: gyrB; PRK05644
553482003933	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
553482003934	Mg2+ binding site [ion binding]; other site
553482003935	G-X-G motif; other site
553482003936	TopoIIA_Trans_DNA_gyrase: Transducer domain, having a ribosomal S5 domain 2-like fold, of the type found in proteins of the type IIA family of DNA topoisomerases similar to the B subunits of E. coli DNA gyrase and E. coli Topoisomerase IV which are; Region: TopoII_Trans_DNA_gyrase; cd00822
553482003937	anchoring element; other site
553482003938	dimer interface [polypeptide binding]; other site
553482003939	ATP binding site [chemical binding]; other site
553482003940	TOPRIM_TopoIIA_GyrB: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in proteins of the type IIA family of DNA topoisomerases similar to the Escherichia coli GyrB subunit. TopoIIA enzymes cut both strands of the...; Region: TOPRIM_TopoIIA_GyrB; cd03366
553482003941	active site
553482003942	putative metal-binding site [ion binding]; other site
553482003943	DNA gyrase B subunit, carboxyl terminus; Region: DNA_gyraseB_C; pfam00986
553482003944	HMMPfam hit to PF02518, Histidine kinase-, DNA gyrase B-, and H, score 7.1e-27
553482003945	HMMPfam hit to PF00204, DNA gyrase B, score 1.4e-92
553482003946	HMMPfam hit to PF01751, Toprim domain, score 3.9e-09
553482003947	PS00177 DNA topoisomerase II signature.
553482003948	HMMPfam hit to PF00986, DNA gyrase B subunit, carboxyl terminus, score 1.2e-46
553482003949	septation ring formation regulator EzrA; Provisional; Region: PRK04778
553482003950	1 transmembrane helix predicted for SEQ0895 by TMHMM2.0 at aa 5-27
553482003951	HMMPfam hit to PF06160, Septation ring formation regulator, EzrA, score 0
553482003952	Protein of unknown function (DUF1694); Region: DUF1694; pfam07997
553482003953	HMMPfam hit to PF07997, Protein of unknown function (DUF1694), score 6.8e-39
553482003954	enolase; Provisional; Region: eno; PRK00077
553482003955	Enolase: Enolases are homodimeric enzymes that catalyse the reversible dehydration of 2-phospho-D-glycerate to phosphoenolpyruvate as part of the glycolytic and gluconeogenesis pathways. The reaction is facilitated by the presence of metal ions; Region: enolase; cd03313
553482003956	dimer interface [polypeptide binding]; other site
553482003957	metal binding site [ion binding]; metal-binding site
553482003958	substrate binding pocket [chemical binding]; other site
553482003959	HMMPfam hit to PF03952, Enolase, N-terminal domain, score 2e-68
553482003960	HMMPfam hit to PF00113, Enolase, C-terminal TIM barrel domain, score 1.3e-164
553482003961	PS00164 Enolase signature.
553482003963	Cytotoxic translational repressor of toxin-antitoxin stability system [Translation, ribosomal structure and biogenesis / Cell division and chromosome partitioning]; Region: RelE; COG2026
553482003964	HMMPfam hit to PF05016, Plasmid stabilisation system protein, score 2.3e-15
553482003965	HAD superfamily (subfamily IA) hydrolase, TIGR02253; Region: CTE7
553482003966	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
553482003967	motif II; other site
553482003968	HMMPfam hit to PF00702, haloacid dehalogenase-like hydrolase, score 0.0007
553482003969	Predicted extracellular nuclease [General function prediction only]; Region: COG2374
553482003970	YhcR_OBF_like: A subfamily of OB-fold domains similar to the OB folds of Bacillus subtilis YhcR. YhcR is a sugar-nonspecific nuclease, which is active in the presence of Ca2+ and Mn2+. It cleaves RNA endonucleolytically, producing 3'-monophosphate...; Region: YhcR_OBF_like; cd04486
553482003971	generic binding surface II; other site
553482003972	generic binding surface I; other site
553482003973	YhcR_OBF_like: A subfamily of OB-fold domains similar to the OB folds of Bacillus subtilis YhcR. YhcR is a sugar-nonspecific nuclease, which is active in the presence of Ca2+ and Mn2+. It cleaves RNA endonucleolytically, producing 3'-monophosphate...; Region: YhcR_OBF_like; cd04486
553482003974	generic binding surface I; other site
553482003975	generic binding surface II; other site
553482003976	Exonuclease-Endonuclease-Phosphatase (EEP) domain superfamily; Region: EEP; cl00490
553482003977	putative catalytic site [active]
553482003978	putative metal binding site [ion binding]; other site
553482003979	putative phosphate binding site [ion binding]; other site
553482003980	HMMPfam hit to PF03372, Endonuclease/Exonuclease/phosphatase fa, score 3e-17
553482003981	PS00343 Gram-positive cocci surface proteins 'anchoring' hexapeptide.
553482003982	1 transmembrane helix predicted for SEQ0904 by TMHMM2.0 at aa 900-919
553482003983	Predicted membrane protein [Function unknown]; Region: COG4708
553482003984	HMMPfam hit to PF06177, Protein of unknown function (DUF988), score 6.4e-97
553482003985	5 transmembrane helices predicted for SEQ0905 by TMHMM2.0 at aa 10-32, 45-67, 71-93, 109-131 and 135-157
553482003986	NAD-dependent DNA ligase LigA; Validated; Region: ligA; PRK07956
553482003987	NAD+ dependent DNA ligase adenylation domain. DNA ligases catalyze the crucial step of joining the breaks in duplex DNA during DNA replication, repair and recombination, utilizing either ATP or NAD(+) as a cofactor, but using the same basic reaction...; Region: LIGANc; cd00114
553482003988	nucleotide binding pocket [chemical binding]; other site
553482003989	K-X-D-G motif; other site
553482003990	catalytic site [active]
553482003991	NAD-dependent DNA ligase OB-fold domain; Region: DNA_ligase_OB; pfam03120
553482003992	NAD-dependent DNA ligase C4 zinc finger domain; Region: DNA_ligase_ZBD; pfam03119
553482003993	Breast Cancer Suppressor Protein (BRCA1), carboxy-terminal domain. The BRCT domain is found within many DNA damage repair and cell cycle checkpoint proteins. The unique diversity of this domain superfamily allows BRCT modules to interact forming homo...; Region: BRCT; cd00027
553482003994	Dimer interface [polypeptide binding]; other site
553482003995	BRCT sequence motif; other site
553482003996	HMMPfam hit to PF01653, NAD-dependent DNA ligase adenylation, score 6.3e-153
553482003997	PS01055 NAD-dependent DNA ligase signature 1.
553482003998	HMMPfam hit to PF03120, NAD-dependent DNA ligase OB-fold doma, score 3e-46
553482003999	PS01056 NAD-dependent DNA ligase signature 2.
553482004000	HMMPfam hit to PF03119, NAD-dependent DNA ligase C4 zinc fing, score 5.1e-13
553482004001	HMMPfam hit to PF00533, BRCA1 C Terminus (BRCT) domain, score 8.4e-15
553482004002	putative lipid kinase; Reviewed; Region: PRK13055
553482004003	Diacylglycerol kinase catalytic domain; Region: DAGK_cat; pfam00781
553482004004	Diacylglycerol kinase catalytic domain; Region: DAGK_cat; cl17465
553482004005	HMMPfam hit to PF00781, Diacylglycerol kinase catalytic domain (pres, score 6.1e-44
553482004006	Family 41 Carbohydrate-Binding Module from pullulanase-like enzymes; Region: CBM41_pullulanase; cd10315
553482004007	carbohydrate binding site [chemical binding]; other site
553482004008	pullulanase, type I; Region: pulA_typeI; TIGR02104
553482004009	Early set domain associated with the catalytic domain of pullulanase (also called dextrinase and alpha-dextrin endo-1,6-alpha glucosidase); Region: E_set_Pullulanase; cd02860
553482004010	Alpha amylase catalytic domain found in Pullulanase (also called dextrinase; alpha-dextrin endo-1,6-alpha glucosidase), limit dextrinase, and related proteins; Region: AmyAc_Pullulanase_LD-like; cd11341
553482004011	Ca binding site [ion binding]; other site
553482004012	active site
553482004013	catalytic site [active]
553482004014	HMMPfam hit to PF02922, Isoamylase N-terminal domain, score 5.1e-07
553482004015	HMMPfam hit to PF00128, Alpha amylase, catalytic domain, score 8.4e-11
553482004016	CDS contains a frameshift after codon 270. Frameshift occurs at a poly G pentamer. Similar to Streptococcus mutans 1,4-alpha-glucan branching enzyme GlgB UniProt:Q8DT52 (EMBL:AE014133 (628 aa) fasta scores: E()=1.1e-209, 74.682% id in 628 aa
553482004017	HMMPfam hit to PF02922, Isoamylase N-terminal domain, score 3e-18
553482004018	glucose-1-phosphate adenylyltransferase; Provisional; Region: glgC; PRK05293
553482004019	ADP-glucose pyrophosphorylase is involved in the biosynthesis of glycogen or starch; Region: ADP_Glucose_PP; cd02508
553482004020	ligand binding site; other site
553482004021	oligomer interface; other site
553482004022	Glucose-1-phosphate adenylyltransferase, C-terminal Left-handed parallel beta helix (LbH) domain: Glucose-1-phosphate adenylyltransferase is also known as ADP-glucose synthase or ADP-glucose pyrophosphorylase. It catalyzes the first committed and...; Region: LbH_G1P_AT_C; cd04651
553482004023	dimer interface [polypeptide binding]; other site
553482004024	N-terminal domain interface [polypeptide binding]; other site
553482004025	HMMPfam hit to PF00483, Nucleotidyl transferase, score 5.5e-77
553482004026	PS00808 ADP-glucose pyrophosphorylase signature 1.
553482004027	HMMPfam hit to PF00132, Bacterial transferase hexapeptide (th, score 48
553482004028	HMMPfam hit to PF00132, Bacterial transferase hexapeptide (th, score 0.022
553482004029	glucose-1-phosphate adenylyltransferase, GlgD subunit; Region: glgD; TIGR02092
553482004030	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
553482004031	active site
553482004032	Glucose-1-phosphate adenylyltransferase, C-terminal Left-handed parallel beta helix (LbH) domain: Glucose-1-phosphate adenylyltransferase is also known as ADP-glucose synthase or ADP-glucose pyrophosphorylase. It catalyzes the first committed and...; Region: LbH_G1P_AT_C; cd04651
553482004033	dimer interface [polypeptide binding]; other site
553482004034	N-terminal domain interface [polypeptide binding]; other site
553482004035	sulfate 1 binding site; other site
553482004036	HMMPfam hit to PF00483, Nucleotidyl transferase, score 2.5e-05
553482004037	glycogen synthase; Provisional; Region: glgA; PRK00654
553482004038	This family is most closely related to the GT1 family of glycosyltransferases. Glycogen synthase catalyzes the formation and elongation of the alpha-1,4-glucose backbone using ADP-glucose, the second and key step of glycogen biosynthesis. This family...; Region: GT1_Glycogen_synthase_DULL1_like; cd03791
553482004039	ADP-binding pocket [chemical binding]; other site
553482004040	homodimer interface [polypeptide binding]; other site
553482004041	HMMPfam hit to PF08323, Starch synthase catalytic domain, score 4.1e-133
553482004042	HMMPfam hit to PF00534, Glycosyl transferases group, score 6.9e-05
553482004043	This is a family of oligosaccharide phosphorylases. It includes yeast and mammalian glycogen phosphorylases, plant starch/glucan phosphorylase, as well as the maltodextrin phosphorylases of bacteria. The members of this family catalyze the breakdown of...; Region: GT1_Glycogen_Phosphorylase; cd04300
553482004044	homodimer interface [polypeptide binding]; other site
553482004045	glycogen/starch/alpha-glucan phosphorylases; Region: P_ylase; TIGR02093
553482004046	active site pocket [active]
553482004047	HMMPfam hit to PF00343, Carbohydrate phosphorylase, score 0
553482004048	F0F1 ATP synthase subunit C; Provisional; Region: PRK13467
553482004049	HMMPfam hit to PF00137, ATP synthase subunit C, score 0.00057
553482004050	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482004051	2 transmembrane helices predicted for SEQ0915 by TMHMM2.0 at aa 4-26 and 42-64
553482004052	PS00605 ATP synthase c subunit signature.
553482004053	F0F1-type ATP synthase, subunit a [Energy production and conversion]; Region: AtpB; COG0356
553482004054	F0F1 ATP synthase subunit A; Validated; Region: PRK05815
553482004055	HMMPfam hit to PF00119, ATP synthase A chain, score 2.3e-50
553482004056	5 transmembrane helices predicted for SEQ0916 by TMHMM2.0 at aa 15-37, 75-97, 112-134, 167-189 and 199-221
553482004057	PS00449 ATP synthase a subunit signature.
553482004058	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482004059	F0F1-type ATP synthase, subunit b [Energy production and conversion]; Region: AtpF; COG0711
553482004060	F0F1 ATP synthase subunit B; Validated; Region: PRK05759
553482004061	HMMPfam hit to PF00430, ATP synthase B/B' CF(0), score 6.8e-21
553482004062	1 transmembrane helix predicted for SEQ0917 by TMHMM2.0 at aa 12-34
553482004063	F0F1 ATP synthase subunit delta; Validated; Region: PRK05758
553482004064	ATP synthase delta (OSCP) subunit; Region: OSCP; pfam00213
553482004065	F0F1 ATP synthase subunit alpha; Validated; Region: PRK09281
553482004066	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
553482004067	F1 ATP synthase alpha, central domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a proton gradient to...; Region: F1_ATPase_alpha; cd01132
553482004068	beta subunit interaction interface [polypeptide binding]; other site
553482004069	Walker A motif; other site
553482004070	ATP binding site [chemical binding]; other site
553482004071	Walker B motif; other site
553482004072	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
553482004073	HMMPfam hit to PF02874, ATP synthase alpha/beta family, beta-ba, score 1.4e-20
553482004074	HMMPfam hit to PF00006, ATP synthase alpha/beta family, nucleot, score 3.6e-116
553482004075	PS00017 ATP/GTP-binding site motif A (P-loop).
553482004076	PS00152 ATP synthase alpha and beta subunits signature.
553482004077	HMMPfam hit to PF00306, ATP synthase alpha/beta chain, C termin, score 6.1e-37
553482004078	mitochondrial ATP synthase gamma subunit; Region: F1-ATPase_gamma; cd12151
553482004079	core domain interface [polypeptide binding]; other site
553482004080	delta subunit interface [polypeptide binding]; other site
553482004081	epsilon subunit interface [polypeptide binding]; other site
553482004082	HMMPfam hit to PF00231, ATP synthase, score 2.6e-122
553482004083	PS00153 ATP synthase gamma subunit signature.
553482004084	F0F1 ATP synthase subunit beta; Validated; Region: PRK09280
553482004085	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
553482004086	F1 ATP synthase beta subunit, nucleotide-binding domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a...; Region: F1-ATPase_beta; cd01133
553482004087	alpha subunit interaction interface [polypeptide binding]; other site
553482004088	Walker A motif; other site
553482004089	ATP binding site [chemical binding]; other site
553482004090	Walker B motif; other site
553482004091	inhibitor binding site; inhibition site
553482004092	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
553482004093	HMMPfam hit to PF02874, ATP synthase alpha/beta family, beta-ba, score 8.5e-26
553482004094	HMMPfam hit to PF00006, ATP synthase alpha/beta family, nucleot, score 1.1e-98
553482004095	PS00017 ATP/GTP-binding site motif A (P-loop).
553482004096	PS00152 ATP synthase alpha and beta subunits signature.
553482004097	HMMPfam hit to PF00306, ATP synthase alpha/beta chain, C termin, score 7.8e-48
553482004098	ATP synthase CF1 epsilon subunit; Region: atpE; CHL00063
553482004099	mitochondrial ATP synthase delta subunit; Region: F1-ATPase_delta; cd12152
553482004100	gamma subunit interface [polypeptide binding]; other site
553482004101	epsilon subunit interface [polypeptide binding]; other site
553482004102	LBP interface [polypeptide binding]; other site
553482004103	HMMPfam hit to PF02823, ATP synthase, Delta/Epsilon chain, beta, score 3.6e-30
553482004104	HMMPfam hit to PF00401, ATP synthase, Delta/Epsilon chain, long, score 1.4e-08
553482004105	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
553482004106	Transposase; Region: HTH_Tnp_1; cl17663
553482004107	HMMPfam hit to PF01527, Transposase, score 0.00051
553482004108	putative transposase OrfB; Reviewed; Region: PHA02517
553482004109	HTH-like domain; Region: HTH_21; pfam13276
553482004110	Integrase core domain; Region: rve; pfam00665
553482004111	Integrase core domain; Region: rve_2; pfam13333
553482004112	HMMPfam hit to PF00665, Integrase core domain, score 1.1e-39
553482004113	Protein of unknown function (DUF1146); Region: DUF1146; cl11486
553482004114	2 transmembrane helices predicted for SEQ0925 by TMHMM2.0 at aa 7-26 and 41-60
553482004115	UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Region: murA; TIGR01072
553482004116	UDP-N-acetylglucosamine enolpyruvyl transferase catalyzes enolpyruvyl transfer as part of the first step in the biosynthesis of peptidoglycan, a component of the bacterial cell wall. The reaction is phosphoenolpyruvate + UDP-N-acetyl-D-glucosamine =...; Region: UdpNAET; cd01555
553482004117	hinge; other site
553482004118	active site
553482004119	HMMPfam hit to PF00275, EPSP synthase (3-phosphoshikimate 1-car, score 3e-129
553482004120	PS00041 Bacterial regulatory proteins, araC family signature.
553482004121	DNA-directed RNA polymerase subunit beta; Region: EpuA; pfam11772
553482004122	1 transmembrane helix predicted for SEQ0927 by TMHMM2.0 at aa 12-34
553482004123	DNA/RNA non-specific endonuclease; Region: Endonuclease_NS; smart00892
553482004124	DNA/RNA non-specific endonuclease; Region: Endonuclea_NS_2; cl17626
553482004125	1 transmembrane helix predicted for SEQ0928 by TMHMM2.0 at aa 7-29
553482004126	HMMPfam hit to PF01223, DNA/RNA non-specific endonuclease, score 2.9e-12
553482004127	PS01070 DNA/RNA non-specific endonucleases active site.
553482004128	phenylalanyl-tRNA synthetase subunit alpha; Validated; Region: pheS; PRK00488
553482004129	Aminoacyl tRNA synthetase class II, N-terminal domain; Region: Phe_tRNA-synt_N; pfam02912
553482004130	Phenylalanyl-tRNA synthetase (PheRS) alpha chain catalytic core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure and the presence of three characteristic sequence motifs. This domain is primarily responsible...; Region: PheRS_alpha_core; cd00496
553482004131	dimer interface [polypeptide binding]; other site
553482004132	motif 1; other site
553482004133	active site
553482004134	motif 2; other site
553482004135	motif 3; other site
553482004136	HMMPfam hit to PF02912, Aminoacyl tRNA synthetase class II, N, score 3.2e-28
553482004137	HMMPfam hit to PF01409, tRNA synthetases class II core domain, score 2.2e-170
553482004138	PS00179 Aminoacyl-transfer RNA synthetases class-II signature 1.
553482004139	phenylalanyl-tRNA synthetase subunit beta; Reviewed; Region: pheT; PRK00629
553482004140	tRNA-binding-domain-containing prokaryotic phenylalanly tRNA synthetase (PheRS) beta chain.  PheRS aminoacylate phenylalanine transfer RNAs (tRNAphe). PheRSs belong structurally to class II aminoacyl tRNA synthetases (aaRSs) but, as they aminoacylate...; Region: tRNA_bind_bactPheRS; cd02796
553482004141	putative tRNA-binding site [nucleotide binding]; other site
553482004142	B3/4 domain; Region: B3_4; pfam03483
553482004143	tRNA synthetase B5 domain; Region: B5; smart00874
553482004144	Phenylalanyl-tRNA synthetase (PheRS) beta chain core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure. While class II aaRSs generally aminoacylate the 3'-OH ribose of the appropriate tRNA,  PheRS is an...; Region: PheRS_beta_core; cd00769
553482004145	dimer interface [polypeptide binding]; other site
553482004146	motif 1; other site
553482004147	motif 3; other site
553482004148	motif 2; other site
553482004149	Ferredoxin-fold anticodon binding domain; Region: FDX-ACB; pfam03147
553482004150	HMMPfam hit to PF01588, tRNA binding domain, score 3.1e-20
553482004151	HMMPfam hit to PF03483, B3/4 domain, score 2.6e-94
553482004152	PS00017 ATP/GTP-binding site motif A (P-loop).
553482004153	PS00017 ATP/GTP-binding site motif A (P-loop).
553482004154	HMMPfam hit to PF03484, tRNA synthetase B5 domain, score 2.5e-24
553482004155	HMMPfam hit to PF03147, Ferredoxin-fold anticodon binding domain, score 2e-27
553482004156	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
553482004157	ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms]; Region: SalY; COG0577
553482004158	FtsX-like permease family; Region: FtsX; pfam02687
553482004159	4 transmembrane helices predicted for SEQ0931 by TMHMM2.0 at aa 13-35, 240-262, 282-304 and 324-346
553482004160	HMMPfam hit to PF02687, Predicted permease, score 2.8e-21
553482004161	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
553482004162	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
553482004163	Walker A/P-loop; other site
553482004164	ATP binding site [chemical binding]; other site
553482004165	Q-loop/lid; other site
553482004166	ABC transporter signature motif; other site
553482004167	Walker B; other site
553482004168	D-loop; other site
553482004169	H-loop/switch region; other site
553482004170	HMMPfam hit to PF00005, ABC transporter, score 1.6e-53
553482004171	PS00017 ATP/GTP-binding site motif A (P-loop).
553482004172	PS00211 ABC transporters family signature.
553482004173	1 transmembrane helix predicted for SEQ0933 by TMHMM2.0 at aa 13-32
553482004174	HMMPfam hit to PF01468, GA module, score 3.3e-19
553482004175	HMMPfam hit to PF00746, Gram positive anchor, score 6.2e-12
553482004176	PS00343 Gram-positive cocci surface proteins 'anchoring' hexapeptide.
553482004177	CDS contains a nonsense mutation (ochre) after codon 43. Similar to Streptococcus agalactiae serotype Ia transcriptional regulator, TetR family UniProt:Q3K2A4 (EMBL:CP000114 (176 aa) fasta scores: E()=1.4e-13, 31.765% id in 170 aa
553482004178	Collagen binding domain; Region: Collagen_bind; pfam05737
553482004179	Repeat unit of collagen-binding protein domain B; Region: CollagenBindB; cd00222
553482004180	domain interaction interfaces [polypeptide binding]; other site
553482004181	Repeat unit of collagen-binding protein domain B; Region: CollagenBindB; cd00222
553482004182	domain interaction interfaces [polypeptide binding]; other site
553482004183	Repeat unit of collagen-binding protein domain B; Region: CollagenBindB; cd00222
553482004184	domain interaction interfaces [polypeptide binding]; other site
553482004185	LPXTG-motif cell wall anchor domain; Region: LPXTG_anchor; TIGR01167
553482004186	HMMPfam hit to PF05737, Collagen binding domain, score 1.7e-60
553482004187	HMMPfam hit to PF05738, Cna protein B-type domain, score 0.00033
553482004188	HMMPfam hit to PF05738, Cna protein B-type domain, score 1.7e-07
553482004189	HMMPfam hit to PF05738, Cna protein B-type domain, score 0.032
553482004190	PS00343 Gram-positive cocci surface proteins 'anchoring' hexapeptide.
553482004191	1 transmembrane helix predicted for SEQ0935 by TMHMM2.0 at aa 624-646
553482004192	fimbrial isopeptide formation D2 domain; Region: RrgB_K2N_iso_D2; TIGR04226
553482004193	Domain of unknown function (DUF3244); Region: DUF3244; pfam11589
553482004194	HMMPfam hit to PF05738, Cna protein B-type domain, score 1.3e-08
553482004195	HMMPfam hit to PF00746, Gram positive anchor, score 0.00046
553482004196	PS00343 Gram-positive cocci surface proteins 'anchoring' hexapeptide.
553482004197	1 transmembrane helix predicted for SEQ0936 by TMHMM2.0 at aa 453-475
553482004198	Sortase C (SrtC) or subfamily-3 sortases are membrane cysteine transpeptidases found in Gram-positive bacteria that anchor surface proteins to peptidoglycans of the bacterial cell wall envelope. This involves a transpeptidation reaction in which the...; Region: Sortase_C_3; cd05827
553482004199	active site
553482004200	catalytic site [active]
553482004201	2 transmembrane helices predicted for SEQ0937 by TMHMM2.0 at aa 5-27 and 241-263
553482004202	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482004203	HMMPfam hit to PF04203, Sortase family, score 2e-57
553482004204	YSIRK type signal peptide; Region: YSIRK_signal; cl04650
553482004205	Mac 1; Region: Mac-1; pfam09028
553482004206	HMMPfam hit to PF04650, YSIRK type signal peptide, score 0.00048
553482004207	1 transmembrane helix predicted for SEQ0938 by TMHMM2.0 at aa 21-43
553482004208	HMMPfam hit to PF00746, Gram positive anchor, score 4.1e-10
553482004209	PS00343 Gram-positive cocci surface proteins 'anchoring' hexapeptide.
553482004210	1 transmembrane helix predicted for SEQ0939 by TMHMM2.0 at aa 389-411
553482004211	gene remnant. Similar to the N-terminal region of Shewanella frigidimarina ISSod11, transposase. UniProt:Q3NJZ7 (EMBL:AAIV01000012 (196 aa) fasta scores: E()=3.8e-09, 28.571% id in 105 aa
553482004212	Gram-positive signal peptide, YSIRK family; Region: YSIRK_signal; TIGR01168
553482004213	pullulanase, extracellular, Gram-positive; Region: pullulan_Gpos; TIGR02102
553482004214	Family 41 Carbohydrate-Binding Module from pullulanase-like enzymes; Region: CBM41_pullulanase; cd10315
553482004215	carbohydrate binding site [chemical binding]; other site
553482004216	Family 41 Carbohydrate-Binding Module from pullulanase-like enzymes; Region: CBM41_pullulanase; cd10315
553482004217	carbohydrate binding site [chemical binding]; other site
553482004218	Early set domain associated with the catalytic domain of pullulanase (also called dextrinase and alpha-dextrin endo-1,6-alpha glucosidase); Region: E_set_Pullulanase; cd02860
553482004219	Alpha amylase catalytic domain found in Pullulanase (also called dextrinase; alpha-dextrin endo-1,6-alpha glucosidase), limit dextrinase, and related proteins; Region: AmyAc_Pullulanase_LD-like; cd11341
553482004220	Ca binding site [ion binding]; other site
553482004221	active site
553482004222	catalytic site [active]
553482004223	HMMPfam hit to PF04650, YSIRK type signal peptide, score 2.3e-07
553482004224	2 transmembrane helices predicted for SEQ0944 by TMHMM2.0 at aa 25-47 and 1210-1232
553482004225	HMMPfam hit to PF03714, Bacterial pullanase-associated domain, score 1.9e-41
553482004226	HMMPfam hit to PF03714, Bacterial pullanase-associated domain, score 2.9e-30
553482004227	HMMPfam hit to PF02922, Isoamylase N-terminal domain, score 3.5e-15
553482004228	HMMPfam hit to PF00128, Alpha amylase, catalytic domain, score 1.9e-11
553482004229	HMMPfam hit to PF00746, Gram positive anchor, score 7.8e-05
553482004230	PS00343 Gram-positive cocci surface proteins 'anchoring' hexapeptide.
553482004231	DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog [Transcription]; Region: RpoE; COG1595
553482004232	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
553482004233	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
553482004234	DNA binding residues [nucleotide binding]
553482004235	PS00217 Sugar transport proteins signature 2.
553482004236	HMMPfam hit to PF04542, Sigma-70 region, score 1.5e-14
553482004237	PS01063 Sigma-70 factors ECF subfamily signature.
553482004238	HMMPfam hit to PF08281, Sigma-70, region, score 7.1e-09
553482004239	HMMPfam hit to PF04545, Sigma-70, region, score 0.0005
553482004240	Putative zinc-finger; Region: zf-HC2; pfam13490
553482004241	1 transmembrane helix predicted for SEQ0946 by TMHMM2.0 at aa 78-100
553482004242	Polyphosphate(polyP) polymerase domain of yeast vacuolar transport chaperone (VTC) proteins VTC-2, -3 and- 4, and similar proteins; Region: PolyPPase_VTC_like; cd07750
553482004243	putative metal binding residues [ion binding]; other site
553482004244	signature motif; other site
553482004245	dimer interface [polypeptide binding]; other site
553482004246	active site
553482004247	polyP binding site; other site
553482004248	substrate binding site [chemical binding]; other site
553482004249	acceptor-phosphate pocket; other site
553482004250	magnesium transport protein MgtC; Provisional; Region: PRK15385
553482004251	3 transmembrane helices predicted for SEQ0948 by TMHMM2.0 at aa 20-42, 64-86 and 99-121
553482004252	Predicted helix-turn-helix motif with score 1013.000, SD 2.64 at aa 42-63, sequence HTGTAYSKKFNVSLMTLTVLTA
553482004253	CotH protein; Region: CotH; pfam08757
553482004254	1 transmembrane helix predicted for SEQ0949 by TMHMM2.0 at aa 7-25
553482004255	Glycosyltransferases, probably involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: COG1215
553482004256	CESA_like is  the cellulose synthase superfamily; Region: CESA_like; cd06423
553482004257	DXD motif; other site
553482004258	4 transmembrane helices predicted for SEQ0951 by TMHMM2.0 at aa 13-35, 350-372, 379-401 and 421-443
553482004259	HMMPfam hit to PF03142, Chitin synthase, score 0.00028
553482004260	HMMPfam hit to PF00535, Glycosyl transferase family, score 2.2e-27
553482004261	PS00290 Immunoglobulins and major histocompatibility complex proteins signature.
553482004262	ATP-dependent nuclease subunit B; Region: rexB_recomb; TIGR02774
553482004263	PD-(D/E)XK nuclease superfamily; Region: PDDEXK_1; pfam12705
553482004264	helicase-exonuclease AddAB, AddA subunit, Firmicutes type; Region: addA_Gpos; TIGR02785
553482004265	Family description; Region: UvrD_C_2; pfam13538
553482004266	PD-(D/E)XK nuclease superfamily; Region: PDDEXK_1; pfam12705
553482004267	HMMPfam hit to PF00580, UvrD/REP helicase, score 3.2e-82
553482004268	PS00017 ATP/GTP-binding site motif A (P-loop).
553482004269	PS00225 Crystallins beta and gamma 'Greek key' motif signature.
553482004270	transaminase; Validated; Region: PRK07324
553482004271	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
553482004272	pyridoxal 5'-phosphate binding site [chemical binding]; other site
553482004273	homodimer interface [polypeptide binding]; other site
553482004274	catalytic residue [active]
553482004275	HMMPfam hit to PF00155, Aminotransferase class I and II, score 4.7e-29
553482004276	HMMPfam hit to PF01212, Beta-eliminating lyase, score 0.0024
553482004277	PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site.
553482004278	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
553482004279	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
553482004280	substrate binding pocket [chemical binding]; other site
553482004281	membrane-bound complex binding site; other site
553482004282	hinge residues; other site
553482004283	HMMPfam hit to PF00497, Bacterial extracellular solute-binding prot, score 1.8e-56
553482004284	30S ribosomal protein S21; Reviewed; Region: rpsU; PRK00270
553482004285	HMMPfam hit to PF01165, Ribosomal protein S21, score 1.1e-30
553482004286	PS01181 Ribosomal protein S21 signature.
553482004287	Large-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscL; COG1970
553482004288	large-conductance mechanosensitive channel; Reviewed; Region: mscL; PRK00567
553482004289	2 transmembrane helices predicted for SEQ0958 by TMHMM2.0 at aa 13-35 and 68-87
553482004290	PS01327 Large-conductance mechanosensitive channels mscL family signature.
553482004291	DNA primase; Validated; Region: dnaG; PRK05667
553482004292	CHC2 zinc finger; Region: zf-CHC2; pfam01807
553482004293	DNA primase catalytic core, N-terminal domain; Region: Toprim_N; pfam08275
553482004294	TOPRIM_DnaG_primases: The topoisomerase-primase (TORPIM) nucleotidyl transferase/hydrolase domain found in the active site regions of proteins similar to Escherichia coli DnaG. Primases synthesize RNA primers for the initiation of DNA replication. DnaG...; Region: TOPRIM_DnaG_primases; cd03364
553482004295	active site
553482004296	metal binding site [ion binding]; metal-binding site
553482004297	interdomain interaction site; other site
553482004298	DnaB-helicase binding domain of primase; Region: DnaB_bind; pfam10410
553482004299	HMMPfam hit to PF01807, CHC2 zinc finger, score 9.6e-45
553482004300	HMMPfam hit to PF08275, DNA primase catalytic core, N-terminal domai, score 1.3e-51
553482004301	HMMPfam hit to PF01751, Toprim domain, score 1.4e-16
553482004302	RNA polymerase sigma factor RpoD; Validated; Region: PRK09210
553482004303	Sigma-70 factor, region 1.1; Region: Sigma70_r1_1; pfam03979
553482004304	Sigma-70 factor, region 1.2; Region: Sigma70_r1_2; pfam00140
553482004305	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
553482004306	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
553482004307	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
553482004308	DNA binding residues [nucleotide binding]
553482004309	HMMPfam hit to PF03979, Sigma-70 factor, region, score 1.5e-05
553482004310	HMMPfam hit to PF00140, Sigma-70 factor, region, score 2.2e-15
553482004311	HMMPfam hit to PF04542, Sigma-70 region, score 1.3e-29
553482004312	PS00715 Sigma-70 factors family signature 1.
553482004313	HMMPfam hit to PF04539, Sigma-70 region, score 4.5e-41
553482004314	Predicted helix-turn-helix motif with score 985.000, SD 2.54 at aa 234-255, sequence PTPEQIAERMEMTPDKVREILK
553482004315	HMMPfam hit to PF04545, Sigma-70, region, score 1.3e-24
553482004316	Predicted helix-turn-helix motif with score 1807.000, SD 5.34 at aa 327-348, sequence RTLEDVGKVFNVTRERIRQIEA
553482004317	PS00716 Sigma-70 factors family signature 2.
553482004318	Predicted metal-sulfur cluster biosynthetic enzyme [General function prediction only]; Region: PaaD; COG2151
553482004319	HMMPfam hit to PF01883, Domain of unknown function DUF59, score 1.7e-38
553482004320	dTDP-6-deoxy-L-lyxo-4-hexulose reductase and related proteins, extended (e) SDRs; Region: dTDP_HR_like_SDR_e; cd05254
553482004321	RmlD substrate binding domain; Region: RmlD_sub_bind; pfam04321
553482004322	NADP binding site [chemical binding]; other site
553482004323	active site
553482004324	putative substrate binding site [chemical binding]; other site
553482004325	HMMPfam hit to PF04321, RmlD substrate binding domain, score 4.1e-143
553482004326	HMMPfam hit to PF02719, Polysaccharide biosynthesis protein, score 0.00023
553482004327	HMMPfam hit to PF01370, NAD dependent epimerase/dehydratase f, score 1.1e-18
553482004328	HMMPfam hit to PF01073, 3-beta hydroxysteroid dehydrogenase/i, score 1.1e-05
553482004329	HMMPfam hit to PF07993, Male sterility protein, score 0.00036
553482004330	This family is most closely related to the GT1 family of glycosyltransferases. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can...; Region: GT1_like_6; cd04955
553482004331	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
553482004332	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
553482004333	Subfamily of Glycosyltransferase Family GT2 of unknown function; Region: GT_2_like_d; cd04196
553482004334	Probable Catalytic site; other site
553482004335	HMMPfam hit to PF00535, Glycosyl transferase family, score 4e-21
553482004336	ABC-type polysaccharide/polyol phosphate export systems, permease component [Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: TagG; COG1682
553482004337	ABC-2 type transporter; Region: ABC2_membrane; pfam01061
553482004338	HMMPfam hit to PF01061, ABC-2 type transporter, score 1e-15
553482004339	6 transmembrane helices predicted for SEQ0965 by TMHMM2.0 at aa 28-50, 65-87, 107-129, 144-166, 173-195 and 235-257
553482004340	ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: TagH; COG1134
553482004341	ATP-binding cassette component of polysaccharide transport system; Region: ABC_KpsT_Wzt; cd03220
553482004342	Walker A/P-loop; other site
553482004343	ATP binding site [chemical binding]; other site
553482004344	Q-loop/lid; other site
553482004345	ABC transporter signature motif; other site
553482004346	Walker B; other site
553482004347	D-loop; other site
553482004348	H-loop/switch region; other site
553482004349	HMMPfam hit to PF00005, ABC transporter, score 2.3e-39
553482004350	PS00017 ATP/GTP-binding site motif A (P-loop).
553482004351	PS00211 ABC transporters family signature.
553482004352	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
553482004353	Glycosyl transferase family 2; Region: Glycos_transf_2; pfam00535
553482004354	active site
553482004355	HMMPfam hit to PF00535, Glycosyl transferase family, score 5.9e-32
553482004356	Rhamnan synthesis protein F; Region: RgpF; pfam05045
553482004357	HMMPfam hit to PF05045, Rhamnan synthesis protein F, score 3.3e-280
553482004358	dolichyl-phosphate beta-D-mannosyltransferase; Region: PLN02726
553482004359	DPM_DPG-synthase_like is a member of the Glycosyltransferase 2 superfamily; Region: DPM_DPG-synthase_like; cd04179
553482004360	Ligand binding site; other site
553482004361	Putative Catalytic site; other site
553482004362	DXD motif; other site
553482004363	HMMPfam hit to PF00535, Glycosyl transferase family, score 2.2e-31
553482004364	3 transmembrane helices predicted for SEQ0970 by TMHMM2.0 at aa 4-21, 34-56 and 66-85
553482004365	Membrane protein involved in the export of O-antigen and teichoic acid [General function prediction only]; Region: RfbX; COG2244
553482004366	Polysaccharide biosynthesis protein; Region: Polysacc_synt_3; pfam13440
553482004367	12 transmembrane helices predicted for SEQ0971 by TMHMM2.0 at aa 13-35, 46-63, 83-102, 112-134, 147-164, 168-186, 207-226, 246-268, 295-317, 332-354, 361-380 and 385-407
553482004368	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482004369	Predicted membrane protein [Function unknown]; Region: COG4713
553482004370	12 transmembrane helices predicted for SEQ0972 by TMHMM2.0 at aa 15-33, 40-57, 61-80, 151-173, 178-200, 227-244, 259-281, 294-316, 370-392, 405-427, 442-461 and 473-490
553482004371	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
553482004372	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
553482004373	HMMPfam hit to PF00534, Glycosyl transferases group, score 7.4e-28
553482004374	Sulfatase; Region: Sulfatase; pfam00884
553482004375	8 transmembrane helices predicted for SEQ0974 by TMHMM2.0 at aa 18-40, 57-74, 136-158, 163-185, 195-217, 222-241, 269-291 and 303-325
553482004376	HMMPfam hit to PF00884, Sulfatase, score 4.4e-56
553482004377	UDP-glucose 4-epimerase; Region: PLN02240
553482004378	UDP-glucose 4 epimerase, subgroup 1, extended (e) SDRs; Region: UDP_G4E_1_SDR_e; cd05247
553482004379	NAD binding site [chemical binding]; other site
553482004380	homodimer interface [polypeptide binding]; other site
553482004381	active site
553482004382	substrate binding site [chemical binding]; other site
553482004383	HMMPfam hit to PF02719, Polysaccharide biosynthesis protein, score 0.0043
553482004384	HMMPfam hit to PF01370, NAD dependent epimerase/dehydratase f, score 1.4e-78
553482004385	HMMPfam hit to PF01073, 3-beta hydroxysteroid dehydrogenase/i, score 3.6e-07
553482004386	HMMPfam hit to PF07993, Male sterility protein, score 0.0016
553482004387	peptidase T; Region: peptidase-T; TIGR01882
553482004388	M20 Peptidase T specifically cleaves tripeptides; Region: M20_peptT; cd03892
553482004389	metal binding site [ion binding]; metal-binding site
553482004390	dimer interface [polypeptide binding]; other site
553482004391	PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1.
553482004392	HMMPfam hit to PF01546, Peptidase family M20/M25/M40, score 0.00027
553482004393	PS00759 ArgE / dapE / ACY1 / CPG2 / yscS family signature 2.
553482004394	HMMPfam hit to PF07687, Peptidase dimerisation domain, score 3.4e-22
553482004395	2 transmembrane helices predicted for SEQ0977 by TMHMM2.0 at aa 20-38 and 45-67
553482004396	Ferredoxin [Energy production and conversion]; Region: Fer; COG1141
553482004397	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
553482004398	1 transmembrane helix predicted for SEQ0979 by TMHMM2.0 at aa 30-52
553482004399	cytidylate kinase; Provisional; Region: cmk; PRK00023
553482004400	Cytidine monophosphate kinase (CMPK) catalyzes the reversible phosphorylation of cytidine monophosphate (CMP) to produce cytidine diphosphate (CDP), using ATP as the preferred phosphoryl donor; Region: CMPK; cd02020
553482004401	CMP-binding site; other site
553482004402	The sites determining sugar specificity; other site
553482004403	PS00017 ATP/GTP-binding site motif A (P-loop).
553482004404	HMMPfam hit to PF02224, Cytidylate kinase, score 4.3e-63
553482004405	translation initiation factor IF-3; Reviewed; Region: infC; PRK00028
553482004406	Translation initiation factor IF-3, N-terminal domain; Region: IF3_N; pfam05198
553482004407	Translation initiation factor IF-3, C-terminal domain; Region: IF3_C; pfam00707
553482004408	HMMPfam hit to PF05198, Translation initiation factor IF-3, N-termin, score 1.1e-47
553482004409	PS00938 Initiation factor 3 signature.
553482004410	HMMPfam hit to PF00707, Translation initiation factor IF-3, C-termin, score 1.4e-44
553482004411	50S ribosomal protein L35; Reviewed; Region: rpmI; PRK00172
553482004412	HMMPfam hit to PF01632, Ribosomal protein L35, score 7.4e-20
553482004413	Ribosomal protein L20; Region: Ribosomal_L20; cd07026
553482004414	23S rRNA binding site [nucleotide binding]; other site
553482004415	L21 binding site [polypeptide binding]; other site
553482004416	L13 binding site [polypeptide binding]; other site
553482004417	HMMPfam hit to PF00453, Ribosomal protein L20, score 3.2e-66
553482004418	PS00937 Ribosomal protein L20 signature.
553482004419	Predicted helix-turn-helix motif with score 1159.000, SD 3.13 at aa 63-84, sequence TRINAAARMNGLSYSQLMHGLK
553482004420	3 transmembrane helices predicted for SEQ0984 by TMHMM2.0 at aa 7-26, 105-127 and 134-156
553482004421	HMMPfam hit to PF00746, Gram positive anchor, score 1.7e-05
553482004422	PS00343 Gram-positive cocci surface proteins 'anchoring' hexapeptide.
553482004423	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily [Cell envelope biogenesis, outer membrane]; Region: MdoB; COG1368
553482004424	Sulfatase; Region: Sulfatase; pfam00884
553482004425	HMMPfam hit to PF00884, Sulfatase, score 7.2e-30
553482004426	5 transmembrane helices predicted for SEQ0985 by TMHMM2.0 at aa 13-35, 45-67, 74-96, 126-148 and 161-180
553482004427	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
553482004428	Helix-turn-helix domain; Region: HTH_28; pfam13518
553482004429	Predicted helix-turn-helix motif with score 1140.000, SD 3.07 at aa 19-40, sequence KSIKCLSEKFSIAESDLKYMIR
553482004430	HMMPfam hit to PF01527, Transposase, score 0.00062
553482004431	HMMPfam hit to PF02178, no description, score 0.21
553482004432	putative transposase OrfB; Reviewed; Region: PHA02517
553482004433	HTH-like domain; Region: HTH_21; pfam13276
553482004434	Integrase core domain; Region: rve; pfam00665
553482004435	Integrase core domain; Region: rve_2; pfam13333
553482004436	HMMPfam hit to PF00665, Integrase core domain, score 1.2e-37
553482004437	Predicted SAM-dependent methyltransferases [General function prediction only]; Region: COG1092
553482004438	Middle domain of the SAM-dependent methyltransferase RlmI and related proteins; Region: RlmI_M_like; cd11572
553482004439	putative RNA binding site [nucleotide binding]; other site
553482004440	Methyltransferase domain; Region: Methyltransf_26; pfam13659
553482004441	3-dehydroquinate dehydratase [Amino acid transport and metabolism]; Region: AroD; COG0710
553482004442	Type I 3-dehydroquinase, (3-dehydroquinate dehydratase or DHQase); Region: DHQase_I; cd00502
553482004443	active site
553482004444	catalytic residue [active]
553482004445	dimer interface [polypeptide binding]; other site
553482004446	HMMPfam hit to PF01487, Type I 3-dehydroquinase, score 1.3e-39
553482004447	Chorismate synthase [Amino acid transport and metabolism]; Region: AroC; COG0082
553482004448	Chorismase synthase, the enzyme catalyzing the final step of the shikimate pathway; Region: Chorismate_synthase; cd07304
553482004449	Tetramer interface [polypeptide binding]; other site
553482004450	active site
553482004451	FMN-binding site [chemical binding]; other site
553482004452	HMMPfam hit to PF01264, Chorismate synthase, score 2.3e-161
553482004453	PS00787 Chorismate synthase signature 1.
553482004454	PS00788 Chorismate synthase signature 2.
553482004455	hypothetical protein; Provisional; Region: PRK13676
553482004456	HMMPfam hit to PF06133, Protein of unknown function (DUF964), score 3.9e-56
553482004457	glutathione reductase; Validated; Region: PRK06116
553482004458	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
553482004459	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
553482004460	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
553482004461	HMMPfam hit to PF01266, FAD dependent oxidoreductase, score 0.00095
553482004462	HMMPfam hit to PF07992, Pyridine nucleotide-disulphide oxidored, score 3.7e-64
553482004463	PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site.
553482004464	HMMPfam hit to PF00070, Pyridine nucleotide-disulphide oxidored, score 3.4e-30
553482004465	HMMPfam hit to PF02852, Pyridine nucleotide-disulphide oxidored, score 8.8e-51
553482004466	cytoskeletal protein RodZ; Provisional; Region: PRK10856
553482004467	Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes [Amino acid transport and metabolism]; Region: NifS; COG1104
553482004468	cysteine desulfurase NifS; Region: FeS_nifS; TIGR03402
553482004469	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
553482004470	catalytic residue [active]
553482004471	HMMPfam hit to PF00266, Aminotransferase class-V, score 5.9e-71
553482004472	HMMPfam hit to PF01212, Beta-eliminating lyase, score 0.0014
553482004473	PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site.
553482004474	thiamine biosynthesis protein ThiI; Provisional; Region: PRK01565
553482004475	THUMP domain of thiamine biosynthesis protein ThiI; Region: THUMP_ThiI; cd11716
553482004476	ThiI is required for thiazole synthesis in the thiamine biosynthesis pathway. It belongs to the Adenosine Nucleotide Hydrolysis suoerfamily and predicted to bind to Adenosine nucleotide; Region: ThiI; cd01712
553482004477	Ligand Binding Site [chemical binding]; other site
553482004478	HMMPfam hit to PF02926, THUMP domain, score 5.4e-15
553482004479	HMMPfam hit to PF02568, Thiamine biosynthesis protein (ThiI), score 7.3e-94
553482004480	HMMPfam hit to PF06508, ExsB, score 0.0012
553482004481	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482004482	Mac 1; Region: Mac-1; pfam09028
553482004483	1 transmembrane helix predicted for SEQ0999 by TMHMM2.0 at aa 12-34
553482004484	1 transmembrane helix predicted for SEQ1001 by TMHMM2.0 at aa 15-37
553482004485	Uncharacterized conserved protein [Function unknown]; Region: COG0398
553482004486	SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335
553482004487	5 transmembrane helices predicted for SEQ1002 by TMHMM2.0 at aa 15-34, 55-74, 89-111, 143-162 and 172-194
553482004488	6 transmembrane helices predicted for SEQ1003 by TMHMM2.0 at aa 13-35, 58-80, 110-132, 160-182, 189-211 and 235-257
553482004489	ABC-type Na+ transport system, ATPase component [Energy production and conversion / Inorganic ion transport and metabolism]; Region: NatA; COG4555
553482004490	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
553482004491	Walker A/P-loop; other site
553482004492	ATP binding site [chemical binding]; other site
553482004493	Q-loop/lid; other site
553482004494	ABC transporter signature motif; other site
553482004495	Walker B; other site
553482004496	D-loop; other site
553482004497	H-loop/switch region; other site
553482004498	HMMPfam hit to PF00005, ABC transporter, score 9.9e-34
553482004499	PS00017 ATP/GTP-binding site motif A (P-loop).
553482004500	Predicted transcriptional regulators [Transcription]; Region: COG1725
553482004501	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
553482004502	DNA-binding site [nucleotide binding]; DNA binding site
553482004503	HMMPfam hit to PF00392, Bacterial regulatory proteins, gntR family, score 2.4e-10
553482004504	Predicted helix-turn-helix motif with score 1258.000, SD 3.47 at aa 35-56, sequence PTVREYAEIAGVNPNTMQRALT
553482004505	DNA polymerase III DnaE; Reviewed; Region: dnaE; PRK07279
553482004506	Polymerase and Histidinol Phosphatase domain of alpha-subunit of bacterial polymerase III; Region: PHP_PolIIIA; cd07431
553482004507	active site
553482004508	PHP Thumb interface [polypeptide binding]; other site
553482004509	DnaE_OBF: A subfamily of OB folds corresponding to the C-terminal OB-fold nucleic acid binding domain of Thermus aquaticus and Escherichia coli type C replicative DNA polymerase III alpha subunit (DnaE). The DNA polymerase holoenzyme of E. coli contains...; Region: DnaE_OBF; cd04485
553482004510	generic binding surface II; other site
553482004511	generic binding surface I; other site
553482004512	HMMPfam hit to PF02811, PHP domain, score 1.1e-07
553482004513	HMMPfam hit to PF07733, Bacterial DNA polymerase III alpha sub, score 5.3e-242
553482004514	HMMPfam hit to PF01336, OB-fold nucleic acid binding domain, score 3.3e-11
553482004515	putative transposase OrfB; Reviewed; Region: PHA02517
553482004516	HTH-like domain; Region: HTH_21; pfam13276
553482004517	Integrase core domain; Region: rve; pfam00665
553482004518	Integrase core domain; Region: rve_2; pfam13333
553482004519	HMMPfam hit to PF00665, Integrase core domain, score 1.2e-37
553482004520	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
553482004521	Helix-turn-helix domain; Region: HTH_28; pfam13518
553482004522	HMMPfam hit to PF01527, Transposase, score 0.00062
553482004523	HMMPfam hit to PF02178, no description, score 0.21
553482004524	Predicted helix-turn-helix motif with score 1140.000, SD 3.07 at aa 19-40, sequence KSIKCLSEKFSIAESDLKYMIR
553482004525	Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-biphosphate. The members belong to a subfamily of the PFKA family (cd00363) and include bacterial ATP-dependent...; Region: Bacterial_PFK; cd00763
553482004526	6-phosphofructokinase; Region: PFKA_ATP; TIGR02482
553482004527	active site
553482004528	ADP/pyrophosphate binding site [chemical binding]; other site
553482004529	dimerization interface [polypeptide binding]; other site
553482004530	allosteric effector site; other site
553482004531	fructose-1,6-bisphosphate binding site; other site
553482004532	HMMPfam hit to PF00365, Phosphofructokinase, score 3.8e-173
553482004533	pyruvate kinase; Provisional; Region: PRK05826
553482004534	Pyruvate kinase (PK):  Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low...; Region: Pyruvate_Kinase; cl17342
553482004535	domain interfaces; other site
553482004536	active site
553482004537	HMMPfam hit to PF00224, Pyruvate kinase, barrel domain, score 1.9e-203
553482004538	HMMPfam hit to PF03328, HpcH/HpaI aldolase/citrate lyase family, score 0.0022
553482004539	HMMPfam hit to PF02887, Pyruvate kinase, alpha/beta domain, score 9.7e-51
553482004540	signal peptidase I, bacterial type; Region: sigpep_I_bact; TIGR02227
553482004541	The S24, S26 LexA/signal peptidase superfamily contains LexA-related and type I signal peptidase families. The S24 LexA protein domains include: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC 3.4.21.88), the...; Region: Peptidase_S24_S26; cl10465
553482004542	The S24, S26 LexA/signal peptidase superfamily contains LexA-related and type I signal peptidase families. The S24 LexA protein domains include: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC 3.4.21.88), the...; Region: Peptidase_S24_S26; cl10465
553482004543	1 transmembrane helix predicted for SEQ1013 by TMHMM2.0 at aa 9-28
553482004544	HMMPfam hit to PF00717, Peptidase S24-like, score 0.0004
553482004545	glucosamine--fructose-6-phosphate aminotransferase; Reviewed; Region: PRK00331
553482004546	Glutamine amidotransferases class-II (Gn-AT)_GFAT-type. This domain is found at the N-terminus of glucosamine-6P synthase (GlmS, or GFAT in humans).  The glutaminase domain catalyzes amide nitrogen transfer from glutamine to the appropriate substrate. In...; Region: GFAT; cd00714
553482004547	glutaminase active site [active]
553482004548	SIS (Sugar ISomerase) domain repeat 1 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_1; cd05008
553482004549	dimer interface [polypeptide binding]; other site
553482004550	active site
553482004551	SIS (Sugar ISomerase) domain repeat 2 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_2; cd05009
553482004552	dimer interface [polypeptide binding]; other site
553482004553	active site
553482004554	PS00443 Glutamine amidotransferases class-II active site.
553482004555	HMMPfam hit to PF00310, Glutamine amidotransferases class-II, score 7.4e-29
553482004556	HMMPfam hit to PF01380, SIS domain, score 2.7e-30
553482004557	HMMPfam hit to PF01380, SIS domain, score 8.4e-17
553482004558	Uncharacterized Zn-ribbon-containing protein involved in phosphonate metabolism [Inorganic ion transport and metabolism]; Region: PhnA; COG2824
553482004559	PhnA Zinc-Ribbon; Region: PhnA_Zn_Ribbon; pfam08274
553482004560	PhnA protein; Region: PhnA; pfam03831
553482004561	HMMPfam hit to PF08274, PhnA Zinc-Ribbon, score 3.8e-14
553482004562	HMMPfam hit to PF03831, PhnA protein, score 2.6e-35
553482004563	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
553482004564	dimer interface [polypeptide binding]; other site
553482004565	conserved gate region; other site
553482004566	ABC-ATPase subunit interface; other site
553482004567	HMMPfam hit to PF00528, Binding-protein-dependent transport syst, score 5.8e-33
553482004568	3 transmembrane helices predicted for SEQ1016 by TMHMM2.0 at aa 15-37, 50-72 and 179-201
553482004569	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
553482004570	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
553482004571	Walker A/P-loop; other site
553482004572	ATP binding site [chemical binding]; other site
553482004573	Q-loop/lid; other site
553482004574	ABC transporter signature motif; other site
553482004575	Walker B; other site
553482004576	D-loop; other site
553482004577	H-loop/switch region; other site
553482004578	HMMPfam hit to PF00005, ABC transporter, score 8e-56
553482004579	PS00017 ATP/GTP-binding site motif A (P-loop).
553482004580	PS00211 ABC transporters family signature.
553482004581	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
553482004582	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
553482004583	substrate binding pocket [chemical binding]; other site
553482004584	membrane-bound complex binding site; other site
553482004585	hinge residues; other site
553482004586	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482004587	HMMPfam hit to PF00497, Bacterial extracellular solute-binding prot, score 1.1e-80
553482004588	Predicted Co/Zn/Cd cation transporters [Inorganic ion transport and metabolism]; Region: MMT1; COG0053
553482004589	Cation efflux family; Region: Cation_efflux; pfam01545
553482004590	HMMPfam hit to PF01545, Cation efflux family, score 2.2e-90
553482004591	4 transmembrane helices predicted for SEQ1019 by TMHMM2.0 at aa 15-37, 84-106, 116-138 and 184-206
553482004592	Na+/alanine symporter [Amino acid transport and metabolism]; Region: AlsT; COG1115
553482004593	amino acid carrier protein; Region: agcS; TIGR00835
553482004594	HMMPfam hit to PF01235, Sodium:alanine symporter family, score 2.1e-165
553482004595	11 transmembrane helices predicted for SEQ1020 by TMHMM2.0 at aa 25-47, 71-93, 103-125, 155-177, 192-214, 221-238, 248-270, 316-338, 358-380, 385-407 and 422-444
553482004596	PS00873 Sodium:alanine symporter family signature.
553482004597	ATP-dependent DNA helicase PcrA; Region: pcrA; TIGR01073
553482004598	Part of AAA domain; Region: AAA_19; pfam13245
553482004599	Family description; Region: UvrD_C_2; pfam13538
553482004600	HMMPfam hit to PF00580, UvrD/REP helicase, score 1.2e-222
553482004601	PS00017 ATP/GTP-binding site motif A (P-loop).
553482004602	Predicted membrane protein [Function unknown]; Region: COG2261
553482004603	3 transmembrane helices predicted for SEQ1022 by TMHMM2.0 at aa 4-26, 33-55 and 60-82
553482004604	HMMPfam hit to PF04226, Transglycosylase associated protein, score 2.4e-14
553482004605	2 transmembrane helices predicted for SEQ1023 by TMHMM2.0 at aa 7-26 and 57-79
553482004606	Small integral membrane protein [Function unknown]; Region: COG5547
553482004607	2 transmembrane helices predicted for SEQ1024 by TMHMM2.0 at aa 7-29 and 33-55
553482004608	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1302
553482004609	HMMPfam hit to PF03780, Protein of unknown function (DUF322), score 1.5e-40
553482004610	PS00867 Carbamoyl-phosphate synthase subdomain signature 2.
553482004611	PS00327 Bacterial rhodopsins retinal binding site.
553482004612	CsbD-like; Region: CsbD; pfam05532
553482004613	HMMPfam hit to PF05532, CsbD-like, score 4.7e-21
553482004614	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1302
553482004615	HMMPfam hit to PF03780, Protein of unknown function (DUF322), score 3.2e-42
553482004616	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
553482004617	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
553482004618	DNA-binding site [nucleotide binding]; DNA binding site
553482004619	TrkA-C domain; Region: TrkA_C; pfam02080
553482004620	HMMPfam hit to PF00392, Bacterial regulatory proteins, gntR family, score 2.7e-09
553482004621	Predicted helix-turn-helix motif with score 1173.000, SD 3.18 at aa 36-57, sequence KSRTTIASTFKVSPETARKGLN
553482004622	HMMPfam hit to PF02080, TrkA-C domain, score 3.8e-15
553482004623	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
553482004624	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
553482004625	HMMPfam hit to PF00440, Bacterial regulatory proteins, tetR family, score 2.3e-06
553482004626	Predicted helix-turn-helix motif with score 1070.000, SD 2.83 at aa 28-49, sequence ITVSDLTKKAGVNRGTFYLHYR
553482004627	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
553482004628	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
553482004629	Walker A/P-loop; other site
553482004630	ATP binding site [chemical binding]; other site
553482004631	Q-loop/lid; other site
553482004632	ABC transporter signature motif; other site
553482004633	Walker B; other site
553482004634	D-loop; other site
553482004635	H-loop/switch region; other site
553482004636	HMMPfam hit to PF00005, ABC transporter, score 3.3e-59
553482004637	PS00017 ATP/GTP-binding site motif A (P-loop).
553482004638	PS00211 ABC transporters family signature.
553482004639	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
553482004640	FtsX-like permease family; Region: FtsX; pfam02687
553482004641	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
553482004642	ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms]; Region: SalY; COG0577
553482004643	FtsX-like permease family; Region: FtsX; pfam02687
553482004644	8 transmembrane helices predicted for SEQ1031 by TMHMM2.0 at aa 21-43, 344-366, 397-419, 439-461, 517-539, 750-769, 803-825 and 840-862
553482004645	HMMPfam hit to PF02687, Predicted permease, score 6.2e-29
553482004646	PS00343 Gram-positive cocci surface proteins 'anchoring' hexapeptide.
553482004647	HMMPfam hit to PF02687, Predicted permease, score 2.1e-22
553482004648	Restriction endonuclease S subunits [Defense mechanisms]; Region: HsdS; COG0732
553482004649	Predicted membrane protein [Function unknown]; Region: COG4129
553482004650	Bacterial protein of unknown function (DUF939); Region: DUF939; pfam06081
553482004651	DUF939 C-terminal domain; Region: DUF939_C; pfam11728
553482004652	HMMPfam hit to PF06081, Bacterial protein of unknown function (DUF93, score 5e-133
553482004653	4 transmembrane helices predicted for SEQ1033 by TMHMM2.0 at aa 15-37, 58-80, 84-106 and 119-141
553482004654	Transposase [DNA replication, recombination, and repair]; Region: COG5421
553482004655	Transposase [DNA replication, recombination, and repair]; Region: COG5421
553482004656	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4487
553482004657	Uncharacterized protein conserved in bacteria (DUF2130); Region: DUF2130; pfam09903
553482004658	PS00659 Glycosyl hydrolases family 5 signature.
553482004659	tRNA pseudouridine synthase B; Provisional; Region: truB; PRK02484
553482004660	Pseudouridine synthase, Escherichia coli TruB like; Region: PseudoU_synth_EcTruB; cd02573
553482004661	RNA binding site [nucleotide binding]; other site
553482004662	active site
553482004663	HMMPfam hit to PF01509, TruB family pseudouridylate synthase (N term, score 8.2e-73
553482004664	bifunctional riboflavin kinase/FMN adenylyltransferase; Reviewed; Region: PRK05627
553482004665	FAD synthetase, N-terminal domain of the bifunctional enzyme; Region: FAD_synthetase_N; cd02064
553482004666	active site
553482004667	Riboflavin kinase; Region: Flavokinase; pfam01687
553482004668	HMMPfam hit to PF06574, FAD synthetase, score 3.5e-60
553482004669	HMMPfam hit to PF01687, Riboflavin kinase, score 2.3e-51
553482004670	Arsenate Reductase (ArsC) family, Spx subfamily; Spx is a unique RNA polymerase (RNAP)-binding protein present in bacilli and some mollicutes. It inhibits transcription by binding to the C-terminal domain of the alpha subunit of RNAP, disrupting complex...; Region: ArsC_Spx; cd03032
553482004671	ArsC family; Region: ArsC; pfam03960
553482004672	putative catalytic residues [active]
553482004673	thiol/disulfide switch; other site
553482004674	HMMPfam hit to PF03960, ArsC family, score 1.2e-58
553482004675	hypothetical protein; Provisional; Region: PRK04387
553482004676	HMMPfam hit to PF05256, Uncharacterised protein family (UPF0223), score 6.2e-55
553482004677	Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family [Carbohydrate transport and metabolism]; Region: SuhB; COG0483
553482004678	Inositol-monophosphatase-like domains. This family of phosphatases is dependent on bivalent metal ions such as Mg++, and many members are inhibited by Li+ (which is thought to displace a bivalent ion in the active site). Substrates include fructose-1; Region: IMPase_like; cd01637
553482004679	active site
553482004680	HMMPfam hit to PF00459, Inositol monophosphatase family, score 2e-30
553482004681	rRNA (cytosine-C(5)-)-methyltransferase RsmF; Reviewed; Region: yebU; PRK11933
553482004682	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
553482004683	S-adenosylmethionine binding site [chemical binding]; other site
553482004684	pre-rRNA processing and ribosome biogenesis; Region: Nol1_Nop2_Fmu_2; pfam13636
553482004685	HMMPfam hit to PF01189, NOL1/NOP2/sun family, score 4.2e-24
553482004686	PS00017 ATP/GTP-binding site motif A (P-loop).
553482004687	PBP superfamily domain; Region: PBP_like_2; cl17296
553482004688	HMMPfam hit to PF01547, Bacterial extracellular solute-binding prot, score 3.7e-08
553482004689	1 transmembrane helix predicted for SEQ1042 by TMHMM2.0 at aa 7-26
553482004690	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482004691	PS00017 ATP/GTP-binding site motif A (P-loop).
553482004692	ABC-type phosphate transport system, permease component [Inorganic ion transport and metabolism]; Region: PstC; COG0573
553482004693	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
553482004694	dimer interface [polypeptide binding]; other site
553482004695	conserved gate region; other site
553482004696	putative PBP binding loops; other site
553482004697	ABC-ATPase subunit interface; other site
553482004698	7 transmembrane helices predicted for SEQ1043 by TMHMM2.0 at aa 24-46, 90-112, 127-149, 156-178, 207-229, 242-264 and 279-301
553482004699	HMMPfam hit to PF00528, Binding-protein-dependent transport syst, score 5.9e-22
553482004700	ABC-type phosphate transport system, permease component [Inorganic ion transport and metabolism]; Region: PstA; COG0581
553482004701	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
553482004702	dimer interface [polypeptide binding]; other site
553482004703	conserved gate region; other site
553482004704	putative PBP binding loops; other site
553482004705	ABC-ATPase subunit interface; other site
553482004706	4 transmembrane helices predicted for SEQ1044 by TMHMM2.0 at aa 12-34, 66-88, 109-131 and 258-280
553482004707	HMMPfam hit to PF00528, Binding-protein-dependent transport syst, score 2.9e-36
553482004708	PS00402 Binding-protein-dependent transport systems inner membrane comp. sign.
553482004709	phosphate transporter ATP-binding protein; Provisional; Region: PRK14237
553482004710	ATP-binding cassette domain of the phosphate transport system; Region: ABC_PstB_phosphate_transporter; cd03260
553482004711	Walker A/P-loop; other site
553482004712	ATP binding site [chemical binding]; other site
553482004713	Q-loop/lid; other site
553482004714	ABC transporter signature motif; other site
553482004715	Walker B; other site
553482004716	D-loop; other site
553482004717	H-loop/switch region; other site
553482004718	HMMPfam hit to PF00005, ABC transporter, score 2e-49
553482004719	PS00017 ATP/GTP-binding site motif A (P-loop).
553482004720	PS00211 ABC transporters family signature.
553482004721	phosphate transporter ATP-binding protein; Provisional; Region: PRK14239
553482004722	ATP-binding cassette domain of the phosphate transport system; Region: ABC_PstB_phosphate_transporter; cd03260
553482004723	Walker A/P-loop; other site
553482004724	ATP binding site [chemical binding]; other site
553482004725	Q-loop/lid; other site
553482004726	ABC transporter signature motif; other site
553482004727	Walker B; other site
553482004728	D-loop; other site
553482004729	H-loop/switch region; other site
553482004730	HMMPfam hit to PF00005, ABC transporter, score 2.4e-51
553482004731	PS00017 ATP/GTP-binding site motif A (P-loop).
553482004732	PS00211 ABC transporters family signature.
553482004733	phosphate transport system regulatory protein PhoU; Region: phoU_full; TIGR02135
553482004734	PhoU domain; Region: PhoU; pfam01895
553482004735	PhoU domain; Region: PhoU; pfam01895
553482004736	HMMPfam hit to PF01895, PhoU family, score 9.4e-31
553482004737	HMMPfam hit to PF01895, PhoU family, score 6.7e-12
553482004738	Peptidase M1 Aminopeptidase N family incudes tricorn interacting factor F3, Endoplasmic reticulum aminopeptidase 1 (ERAP1), Aminopeptidase Q (APQ); Region: M1_APN_2; cd09601
553482004739	Aminopeptidase N [Amino acid transport and metabolism]; Region: PepN; COG0308
553482004740	Zn binding site [ion binding]; other site
553482004741	HMMPfam hit to PF01433, Peptidase family M1, score 1.1e-168
553482004742	PS00142 Neutral zinc metallopeptidases, zinc-binding region signature.
553482004743	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
553482004744	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
553482004745	active site
553482004746	phosphorylation site [posttranslational modification]
553482004747	intermolecular recognition site; other site
553482004748	dimerization interface [polypeptide binding]; other site
553482004749	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
553482004750	DNA binding site [nucleotide binding]
553482004751	HMMPfam hit to PF00072, Response regulator receiver domain, score 1.2e-25
553482004752	HMMPfam hit to PF00486, Transcriptional regulatory protein, C te, score 3e-14
553482004753	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
553482004754	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
553482004755	dimer interface [polypeptide binding]; other site
553482004756	phosphorylation site [posttranslational modification]
553482004757	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
553482004758	ATP binding site [chemical binding]; other site
553482004759	Mg2+ binding site [ion binding]; other site
553482004760	G-X-G motif; other site
553482004761	2 transmembrane helices predicted for SEQ1050 by TMHMM2.0 at aa 7-29 and 177-199
553482004762	HMMPfam hit to PF00512, His Kinase A (phosphoacceptor) domain, score 1.4e-10
553482004763	HMMPfam hit to PF02518, Histidine kinase-, DNA gyrase B-, and HSP90, score 7.1e-33
553482004764	1 transmembrane helix predicted for SEQ1051 by TMHMM2.0 at aa 15-34
553482004765	Lipase.  Lipases are esterases that can hydrolyze long-chain acyl-triglycerides into di- and monoglycerides, glycerol, and free fatty acids at a water/lipid interface. A typical feature of lipases is "interfacial activation", the process of...; Region: Lipase; cl14883
553482004766	nucleophilic elbow; other site
553482004767	catalytic triad; other site
553482004768	PS00120 Lipases, serine active site.
553482004769	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482004770	30S ribosomal protein S20; Reviewed; Region: rpsT; PRK00239
553482004771	HMMPfam hit to PF01649, Ribosomal protein S20, score 8.5e-20
553482004772	pantothenate kinase; Provisional; Region: PRK05439
553482004773	Pantothenate kinase (PanK) catalyzes the phosphorylation of pantothenic acid to form 4'-phosphopantothenic, which is the first of five steps in coenzyme A (CoA) biosynthetic pathway. The reaction carried out by this enzyme is a key regulatory point...; Region: PanK; cd02025
553482004774	ATP-binding site [chemical binding]; other site
553482004775	CoA-binding site [chemical binding]; other site
553482004776	Mg2+-binding site [ion binding]; other site
553482004777	HMMPfam hit to PF00485, Phosphoribulokinase / Uridine kinase family, score 4.2e-07
553482004778	PS00017 ATP/GTP-binding site motif A (P-loop).
553482004779	16S RNA G1207 methylase RsmC [Translation, ribosomal structure and biogenesis]; Region: RsmC; COG2813
553482004780	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
553482004781	S-adenosylmethionine binding site [chemical binding]; other site
553482004782	HMMPfam hit to PF05175, Methyltransferase small domain, score 1.8e-73
553482004783	PS00225 Crystallins beta and gamma 'Greek key' motif signature.
553482004784	pyrimidine-nucleoside phosphorylase; Reviewed; Region: PRK06078
553482004785	Glycosyl transferase family, helical bundle domain; Region: Glycos_trans_3N; pfam02885
553482004786	Glycosyl transferase family, a/b domain; Region: Glycos_transf_3; pfam00591
553482004787	Pyrimidine nucleoside phosphorylase C-terminal domain; Region: PYNP_C; pfam07831
553482004788	HMMPfam hit to PF02885, Glycosyl transferase family, helical, score 1.2e-22
553482004789	HMMPfam hit to PF00591, Glycosyl transferase family, a/b doma, score 2.6e-30
553482004790	PS00647 Thymidine and pyrimidine-nucleoside phosphorylases signature.
553482004791	HMMPfam hit to PF07831, Pyrimidine nucleoside phosphorylase C, score 2.4e-25
553482004792	2-deoxyribose-5-phosphate aldolase (DERA) of the DeoC family; Region: DeoC; cd00959
553482004793	intersubunit interface [polypeptide binding]; other site
553482004794	active site
553482004795	catalytic residue [active]
553482004796	HMMPfam hit to PF01791, DeoC/LacD family aldolase, score 2.6e-81
553482004797	Cytidine deaminase zinc-binding domain. These enzymes are Zn dependent. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a water molecule to form a hydroxide ion that performs a nucleophilic attack on...; Region: cytidine_deaminase; cd01283
553482004798	active site
553482004799	catalytic motif [active]
553482004800	Zn binding site [ion binding]; other site
553482004801	HMMPfam hit to PF00383, Cytidine and deoxycytidylate deaminas, score 1.2e-20
553482004802	PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature.
553482004803	Uncharacterized ABC-type transport system, periplasmic component/surface lipoprotein [General function prediction only]; Region: Med; COG1744
553482004804	Periplasmic binding domain of basic membrane lipoprotein, PnrA, in Treponema pallidum and its homologs from other bacteria and Archaea; Region: PBP1_BmpA_PnrA_like; cd06354
553482004805	ligand binding site [chemical binding]; other site
553482004806	HMMPfam hit to PF02608, Basic membrane protein, score 1.4e-73
553482004807	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482004808	PS00017 ATP/GTP-binding site motif A (P-loop).
553482004809	PS00227 Tubulin subunits alpha, beta, and gamma signature.
553482004810	PS00146 Beta-lactamase class-A active site.
553482004811	ABC-type uncharacterized transport systems, ATPase components [General function prediction only]; Region: COG3845
553482004812	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
553482004813	Walker A/P-loop; other site
553482004814	ATP binding site [chemical binding]; other site
553482004815	Q-loop/lid; other site
553482004816	ABC transporter signature motif; other site
553482004817	Walker B; other site
553482004818	D-loop; other site
553482004819	H-loop/switch region; other site
553482004820	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
553482004821	HMMPfam hit to PF00005, ABC transporter, score 2.5e-52
553482004822	PS00017 ATP/GTP-binding site motif A (P-loop).
553482004823	HMMPfam hit to PF00005, ABC transporter, score 5.7e-20
553482004824	PS00211 ABC transporters family signature.
553482004825	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
553482004826	Transmembrane subunit (TM) of Treponema pallidum (Tp) RbsC-1, RbsC-2 and related proteins. This is a functionally uncharacterized subgroup of TMs which belong to a larger group of TMs of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette; Region: TM_PBP1_transp_TpRbsC_like; cd06580
553482004827	TM-ABC transporter signature motif; other site
553482004828	10 transmembrane helices predicted for SEQ1063 by TMHMM2.0 at aa 9-31, 51-70, 75-97, 107-129, 134-156, 194-213, 242-264, 268-290, 295-317 and 322-344
553482004829	HMMPfam hit to PF02653, Branched-chain amino acid transport syst, score 1.4e-55
553482004830	CDS contains a frameshift after codon 47. Frameshift occurs at a poly G octamer. Similar to Streptococcus pyogenes serotype M3 sugar ABC transporter UniProt:Q878Q1 (EMBL:BA000034 (318 aa) fasta scores: E()=3.7e-103, 92.453% id in 318 aa
553482004831	2 transmembrane helices predicted for SEQ1064 by TMHMM2.0 at aa 4-26 and 39-61
553482004832	HMMPfam hit to PF02653, Branched-chain amino acid transport syst, score 5.8e-05
553482004833	6 transmembrane helices predicted for SEQ1065 by TMHMM2.0 at aa 20-42, 77-94, 120-142, 146-168, 173-195 and 205-227
553482004834	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3464
553482004835	Transposase; Region: DDE_Tnp_ISL3; pfam01610
553482004836	HMMPfam hit to PF01610, Transposase, score 1.5e-47
553482004837	Predicted helix-turn-helix motif with score 1424.000, SD 4.04 at aa 118-139, sequence KALTHIASKLAISTSTVYRKLK
553482004838	This CD includes PGM2 (phosphoglucomutase 2) and PGM2L1 (phosphoglucomutase 2-like 1). The mammalian PGM2 is thought to be a phosphopentomutase that catalyzes the conversion of the nucleoside breakdown products, ribose-1-phosphate and...; Region: PGM2; cd05799
553482004839	Phosphomannomutase [Carbohydrate transport and metabolism]; Region: {ManB}; COG1109
553482004840	active site
553482004841	substrate binding site [chemical binding]; other site
553482004842	metal binding site [ion binding]; metal-binding site
553482004843	HMMPfam hit to PF00408, Phosphoglucomutase/phosphomannomutase, C-, score 0.0012
553482004844	HMMPfam hit to PF02880, Phosphoglucomutase/phosphomannomutase, al, score 2e-05
553482004845	HMMPfam hit to PF02879, Phosphoglucomutase/phosphomannomutase, al, score 0.0092
553482004846	HMMPfam hit to PF02878, Phosphoglucomutase/phosphomannomutase, al, score 1.7e-56
553482004847	PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature.
553482004848	Predicted helix-turn-helix motif with score 1215.000, SD 3.33 at aa 75-96, sequence ESKGEAAKKAGVAIAYDSRHFS
553482004849	putative transposase OrfB; Reviewed; Region: PHA02517
553482004850	HTH-like domain; Region: HTH_21; pfam13276
553482004851	Integrase core domain; Region: rve; pfam00665
553482004852	Integrase core domain; Region: rve_2; pfam13333
553482004853	HMMPfam hit to PF00665, Integrase core domain, score 1.1e-37
553482004854	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
553482004855	Helix-turn-helix domain; Region: HTH_28; pfam13518
553482004856	HMMPfam hit to PF01527, Transposase, score 0.00062
553482004857	HMMPfam hit to PF02178, no description, score 0.21
553482004858	Predicted helix-turn-helix motif with score 1140.000, SD 3.07 at aa 19-40, sequence KSIKCLSEKFSIAESDLKYMIR
553482004859	Predicted membrane protein [Function unknown]; Region: COG4684
553482004860	Protein of unknown function (DUF3816); Region: DUF3816; pfam12822
553482004861	5 transmembrane helices predicted for SEQ1072 by TMHMM2.0 at aa 15-37, 62-84, 99-121, 128-150 and 165-187
553482004862	phosphopantothenoylcysteine decarboxylase; Validated; Region: PRK07313
553482004863	Flavoprotein; Region: Flavoprotein; pfam02441
553482004864	HMMPfam hit to PF02441, Flavoprotein, score 6.1e-47
553482004865	phosphopantothenate--cysteine ligase; Validated; Region: PRK06732
553482004866	HMMPfam hit to PF04127, DNA / pantothenate metabolism flavoprotein, score 1.6e-62
553482004867	formate--tetrahydrofolate ligase; Provisional; Region: PRK13505
553482004868	Formyltetrahydrofolate synthetase (FTHFS) catalyzes the ATP-dependent activation of formate ion via its addition to the N10 position of tetrahydrofolate. FTHFS is a highly expressed key enzyme in both the Wood-Ljungdahl pathway of autotrophic CO2...; Region: FTHFS; cd00477
553482004869	Potassium binding sites [ion binding]; other site
553482004870	Cesium cation binding sites [ion binding]; other site
553482004871	HMMPfam hit to PF01268, Formate--tetrahydrofolate ligase, score 0
553482004872	PS00721 Formate--tetrahydrofolate ligase signature 1.
553482004873	CDS contains a frameshift after codon 58 and a nonsense mutation (ochre) after codon 105. CDS appears to be truncated at the C-terminus and lacks a LPxTG motif. Similar to the N-terminal region of Streptococcus agalactiae serotype III hypothetical protein gbs0451 UniProt:Q8E6V8 (EMBL:AL766845 (1233 aa) fasta scores: E()=2.4e-101, 41.704% id in 1115 aa
553482004874	HMMPfam hit to PF00082, Subtilase family, score 2.8e-06
553482004875	HMMPfam hit to PF02225, PA domain, score 3.7e-17
553482004876	PS00138 Serine proteases, subtilase family, serine active site.
553482004877	HMMPfam hit to PF06280, Domain of Unknown Function (DUF1034), score 4.8e-22
553482004878	Phosphatidylserine/phosphatidylglycerophosphate/car diolipin synthases and related enzymes [Lipid metabolism]; Region: Cls; COG1502
553482004879	Putative catalytic domain, repeat 1, of Streptococcus mutans uncharacterized protein SMU_988 and similar proteins; Region: PLDc_SMU_988_like_1; cd09154
553482004880	putative active site [active]
553482004881	catalytic site [active]
553482004882	Putative catalytic domain, repeat 2, of Streptococcus mutans uncharacterized protein SMU_988 and similar proteins; Region: PLDc_SMU_988_like_2; cd09160
553482004883	putative active site [active]
553482004884	catalytic site [active]
553482004885	3 transmembrane helices predicted for SEQ1078 by TMHMM2.0 at aa 20-42, 52-74 and 79-101
553482004886	HMMPfam hit to PF00614, Phospholipase D Active site motif, score 3.7e-10
553482004887	HMMPfam hit to PF00614, Phospholipase D Active site motif, score 5.9e-06
553482004888	Transposase [DNA replication, recombination, and repair]; Region: COG5421
553482004889	Transposase [DNA replication, recombination, and repair]; Region: COG5421
553482004890	aspartate-semialdehyde dehydrogenase; Provisional; Region: PRK14874
553482004891	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
553482004892	HMMPfam hit to PF01118, Semialdehyde dehydrogenase, NAD bindi, score 5.1e-45
553482004893	HMMPfam hit to PF02774, Semialdehyde dehydrogenase, dimerisat, score 1.7e-78
553482004894	ATP cone domain; Region: ATP-cone; pfam03477
553482004895	HMMPfam hit to PF03477, ATP cone domain, score 4e-26
553482004896	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism]; Region: ARO8; COG1167
553482004897	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
553482004898	DNA-binding site [nucleotide binding]; DNA binding site
553482004899	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
553482004900	pyridoxal 5'-phosphate binding site [chemical binding]; other site
553482004901	homodimer interface [polypeptide binding]; other site
553482004902	catalytic residue [active]
553482004903	HMMPfam hit to PF00155, Aminotransferase class I and II, score 3.4e-05
553482004904	Predicted helix-turn-helix motif with score 1266.000, SD 3.50 at aa 174-195, sequence HRMEQLATSLGLPYQTIERDVN
553482004905	HMMPfam hit to PF00392, Bacterial regulatory proteins, gntR fam, score 2.2e-11
553482004906	Predicted helix-turn-helix motif with score 1140.000, SD 3.07 at aa 28-49, sequence PSIRQLSQQYHCSKDTVQRALL
553482004907	pyridoxamine kinase; Validated; Region: PRK07105
553482004908	substrate binding site [chemical binding]; other site
553482004909	ATP binding site [chemical binding]; other site
553482004910	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482004911	ECF-type riboflavin transporter, S component; Region: ECF-ribofla_trS; cl17272
553482004912	6 transmembrane helices predicted for SEQ1084 by TMHMM2.0 at aa 7-25, 29-46, 66-88, 98-115, 122-141 and 145-164
553482004913	PS00178 Aminoacyl-transfer RNA synthetases class-I signature.
553482004914	ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only]; Region: Uup; COG0488
553482004915	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
553482004916	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
553482004917	ABC transporter; Region: ABC_tran_2; pfam12848
553482004918	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
553482004919	HMMPfam hit to PF00005, ABC transporter, score 1e-42
553482004920	PS00017 ATP/GTP-binding site motif A (P-loop).
553482004921	PS00211 ABC transporters family signature.
553482004922	HMMPfam hit to PF00005, ABC transporter, score 4.6e-35
553482004923	PS00017 ATP/GTP-binding site motif A (P-loop).
553482004924	PS00211 ABC transporters family signature.
553482004925	CDS contains a frameshift after codon 160. Similar to Streptococcus pyogenes serotype M1 hypothetical protein Spy1158 (hypothetical protein). UniProt:Q99ZN0 (EMBL:AE006557 (303 aa) fasta scores: E()=2.5e-80, 76.254% id in 299 aa
553482004926	HMMPfam hit to PF00781, Diacylglycerol kinase catalytic domain (pres, score 2.6e-26
553482004927	Predicted membrane protein, hemolysin III homolog [General function prediction only]; Region: COG1272
553482004928	channel protein, hemolysin III family; Region: hlyIII; TIGR01065
553482004929	6 transmembrane helices predicted for SEQ1090 by TMHMM2.0 at aa 20-42, 49-71, 106-128, 141-160, 164-186 and 193-215
553482004930	HMMPfam hit to PF03006, Haemolysin-III related, score 1.5e-59
553482004931	Domain of unknown function (DUF1836); Region: DUF1836; pfam08876
553482004932	Methyltransferase domain; Region: Methyltransf_31; pfam13847
553482004933	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
553482004934	S-adenosylmethionine binding site [chemical binding]; other site
553482004935	HMMPfam hit to PF01209, ubiE/COQ5 methyltransferase family, score 0.00059
553482004936	HMMPfam hit to PF08241, Methyltransferase domain, score 3.1e-25
553482004937	HMMPfam hit to PF08242, Methyltransferase domain, score 6.9e-11
553482004938	Uncharacterized conserved protein, contains double-stranded beta-helix domain [Function unknown]; Region: COG1917
553482004939	HMMPfam hit to PF07883, Cupin domain, score 6.5e-10
553482004940	Response regulator of the LytR/AlgR family [Transcription / Signal transduction mechanisms]; Region: LytT; COG3279
553482004941	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
553482004942	active site
553482004943	phosphorylation site [posttranslational modification]
553482004944	intermolecular recognition site; other site
553482004945	dimerization interface [polypeptide binding]; other site
553482004946	LytTr DNA-binding domain; Region: LytTR; pfam04397
553482004947	HMMPfam hit to PF00072, Response regulator receiver domain, score 0.00028
553482004948	HMMPfam hit to PF04397, LytTr DNA-binding domain, score 1.4e-25
553482004949	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
553482004950	ABC-type multidrug transport system, ATPase component; Region: ABC_drug_resistance_like; cd03264
553482004951	Walker A/P-loop; other site
553482004952	ATP binding site [chemical binding]; other site
553482004953	Q-loop/lid; other site
553482004954	ABC transporter signature motif; other site
553482004955	Walker B; other site
553482004956	D-loop; other site
553482004957	H-loop/switch region; other site
553482004958	HMMPfam hit to PF00005, ABC transporter, score 4.1e-47
553482004959	PS00017 ATP/GTP-binding site motif A (P-loop).
553482004960	PS00211 ABC transporters family signature.
553482004961	CDS is truncated by the insertion of the downstream IS element. Similar to the C-terminal region of Streptococcus agalactiae serotype III hypothetical protein GBS1941 UniProt:Q8E322 (EMBL:AL766854 (384 aa) fasta scores: E()=4.9e-60, 52.023% id in 346 aa
553482004962	5 transmembrane helices predicted for SEQ1098 by TMHMM2.0 at aa 17-39, 160-182, 207-229, 266-288 and 295-317
553482004963	putative transposase OrfB; Reviewed; Region: PHA02517
553482004964	HTH-like domain; Region: HTH_21; pfam13276
553482004965	Integrase core domain; Region: rve; pfam00665
553482004966	Integrase core domain; Region: rve_2; pfam13333
553482004967	HMMPfam hit to PF00665, Integrase core domain, score 1.1e-37
553482004968	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
553482004969	Helix-turn-helix domain; Region: HTH_28; pfam13518
553482004970	HMMPfam hit to PF01527, Transposase, score 0.00062
553482004971	HMMPfam hit to PF02178, no description, score 0.21
553482004972	Predicted helix-turn-helix motif with score 1140.000, SD 3.07 at aa 19-40, sequence KSIKCLSEKFSIAESDLKYMIR
553482004973	CDS is truncated by the insertion of the upstream IS element
553482004974	Site-specific recombinases, DNA invertase Pin homologs [DNA replication, recombination, and repair]; Region: PinR; COG1961
553482004975	Serine Recombinase family, catalytic domain; a DNA binding domain may be present either N- or C-terminal to the catalytic domain. These enzymes perform site-specific recombination of DNA molecules by a concerted, four-strand cleavage and rejoining...; Region: Ser_Recombinase; cl02788
553482004976	catalytic residues [active]
553482004977	catalytic nucleophile [active]
553482004978	Recombinase; Region: Recombinase; pfam07508
553482004979	Recombinase zinc beta ribbon domain; Region: Zn_ribbon_recom; pfam13408
553482004980	HMMPfam hit to PF00239, Resolvase, N terminal domain, score 0.00042
553482004981	HMMPfam hit to PF07508, Recombinase, score 1.7e-22
553482004982	gene remnant. CDS is truncated by recombination event. N-terminal region of the this CDS is SEQ1276. Similar to the C-terminal region of Streptococcus suis ABC transporter permease UniProt:Q8VVF9 (EMBL:AJ416309 (257 aa) fasta scores: E()=1.2e-35, 71.939% id in 196 aa
553482004983	HMMPfam hit to PF00005, ABC transporter, score 3.9e-34
553482004984	PS00211 ABC transporters family signature.
553482004985	Mevalonate kinase [Lipid metabolism]; Region: ERG12; COG1577
553482004986	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
553482004987	HMMPfam hit to PF00288, GHMP kinases N terminal domain, score 1.2e-14
553482004988	HMMPfam hit to PF08544, GHMP kinases C terminal, score 1.5e-12
553482004989	diphosphomevalonate decarboxylase; Region: PLN02407
553482004990	diphosphomevalonate decarboxylase; Region: mevDPdecarb; TIGR01240
553482004991	HMMPfam hit to PF00288, GHMP kinases N terminal domain, score 1.5e-11
553482004992	PS00627 GHMP kinases ATP-binding domain.
553482004993	HMMPfam hit to PF08544, GHMP kinases C terminal, score 1e-08
553482004994	Mevalonate kinase [Lipid metabolism]; Region: ERG12; COG1577
553482004995	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
553482004996	HMMPfam hit to PF00288, GHMP kinases N terminal domain, score 2.5e-07
553482004997	HMMPfam hit to PF08544, GHMP kinases C terminal, score 9.8e-08
553482004998	isopentenyl pyrophosphate isomerase; Provisional; Region: PRK05437
553482004999	Isopentenyl-diphosphate:dimethylallyl diphosphate isomerase type 2 (IDI-2) FMN-binding domain. Two types of IDIs have been characterized at present. The long known IDI-1 is only dependent on divalent metals for activity, whereas IDI-2 requires a metal; Region: IDI-2_FMN; cd02811
553482005000	homotetramer interface [polypeptide binding]; other site
553482005001	FMN binding site [chemical binding]; other site
553482005002	homodimer contacts [polypeptide binding]; other site
553482005003	putative active site [active]
553482005004	putative substrate binding site [chemical binding]; other site
553482005005	HMMPfam hit to PF01070, FMN-dependent dehydrogenase, score 2e-05
553482005006	Class II hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase (HMGR); Region: HMG-CoA_reductase_classII; cd00644
553482005007	homodimer interface [polypeptide binding]; other site
553482005008	catalytic residues [active]
553482005009	NAD binding site [chemical binding]; other site
553482005010	substrate binding pocket [chemical binding]; other site
553482005011	flexible flap; other site
553482005012	"initiating" condensing enzymes are a subclass of decarboxylating condensing enzymes, including beta-ketoacyl [ACP] synthase, type III and polyketide synthases, type III, which include chalcone synthase and related enzymes. They are...; Region: init_cond_enzymes; cd00827
553482005013	3-hydroxy-3-methylglutaryl CoA synthase, prokaryotic clade; Region: HMG-CoA-S_prok; TIGR01835
553482005014	dimer interface [polypeptide binding]; other site
553482005015	active site
553482005016	HMMPfam hit to PF08540, Hydroxymethylglutaryl-coenzyme A synth, score 1.9e-11
553482005017	HMMPfam hit to PF01154, Hydroxymethylglutaryl-coenzyme A synth, score 7.7e-08
553482005018	thymidylate synthase; Reviewed; Region: thyA; PRK01827
553482005019	Thymidylate synthase and pyrimidine hydroxymethylase: Thymidylate synthase (TS) and deoxycytidylate hydroxymethylase (dCMP-HMase) are homologs that catalyze analogous alkylation of C5 of pyrimidine nucleotides. Both enzymes are involved in the...; Region: TS_Pyrimidine_HMase; cd00351
553482005020	dimerization interface [polypeptide binding]; other site
553482005021	active site
553482005022	HMMPfam hit to PF00303, Thymidylate synthase, score 4e-105
553482005023	Dihydrofolate reductase [Coenzyme metabolism]; Region: FolA; COG0262
553482005024	Dihydrofolate reductase (DHFR). Reduces 7,8-dihydrofolate to 5,6,7,8-tetrahydrofolate with NADPH as a cofactor. This is an essential step in the biosynthesis of deoxythymidine phosphate since 5,6,7,8-tetrahydrofolate is required to regenerate 5; Region: DHFR; cd00209
553482005025	folate binding site [chemical binding]; other site
553482005026	NADP+ binding site [chemical binding]; other site
553482005027	HMMPfam hit to PF00186, Dihydrofolate reductase, score 1.1e-26
553482005028	PS00075 Dihydrofolate reductase signature.
553482005029	2 transmembrane helices predicted for SEQ1112 by TMHMM2.0 at aa 5-24 and 31-53
553482005030	ATP-dependent protease ATP-binding subunit ClpX; Provisional; Region: clpX; PRK05342
553482005031	ClpX C4-type zinc finger; Region: zf-C4_ClpX; pfam06689
553482005032	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
553482005033	Walker A motif; other site
553482005034	ATP binding site [chemical binding]; other site
553482005035	Walker B motif; other site
553482005036	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
553482005037	HMMPfam hit to PF06689, ClpX C4-type zinc finger, score 1.2e-23
553482005038	HMMPfam hit to PF07724, ATPase family associated with various cell, score 1.1e-80
553482005039	HMMPfam hit to PF00004, ATPase family associated with various cell, score 5.9e-06
553482005040	PS00017 ATP/GTP-binding site motif A (P-loop).
553482005041	YihA (EngB) GTPase family; Region: YihA_EngB; cd01876
553482005042	G1 box; other site
553482005043	GTP/Mg2+ binding site [chemical binding]; other site
553482005044	Switch I region; other site
553482005045	G2 box; other site
553482005046	G3 box; other site
553482005047	Switch II region; other site
553482005048	G4 box; other site
553482005049	G5 box; other site
553482005050	HMMPfam hit to PF01926, GTPase of unknown function, score 5.2e-35
553482005051	PS00017 ATP/GTP-binding site motif A (P-loop).
553482005052	Leucine rich repeats (6 copies); Region: LRR_5; pfam13306
553482005053	Leucine rich repeats (6 copies); Region: LRR_5; pfam13306
553482005054	PS00343 Gram-positive cocci surface proteins 'anchoring' hexapeptide.
553482005055	1 transmembrane helix predicted for SEQ1116 by TMHMM2.0 at aa 974-991
553482005056	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
553482005057	ATPases associated with a variety of cellular activities; Region: AAA; smart00382
553482005058	Walker A motif; other site
553482005059	ATP binding site [chemical binding]; other site
553482005060	Walker B motif; other site
553482005061	arginine finger; other site
553482005062	UvrB/uvrC motif; Region: UVR; pfam02151
553482005063	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
553482005064	Walker A motif; other site
553482005065	ATP binding site [chemical binding]; other site
553482005066	Walker B motif; other site
553482005067	arginine finger; other site
553482005068	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431
553482005069	HMMPfam hit to PF07728, ATPase family associated with various cellul, score 8.3e-05
553482005070	HMMPfam hit to PF07724, ATPase family associated with various cellul, score 6.6e-77
553482005071	PS00017 ATP/GTP-binding site motif A (P-loop).
553482005072	HMMPfam hit to PF00004, ATPase family associated with various cellul, score 5.3e-12
553482005073	PS00017 ATP/GTP-binding site motif A (P-loop).
553482005074	Nucleoside diphosphate kinase Group I (NDPk_I)-like: NDP kinase domains are present in a large family of structurally and functionally conserved proteins from bacteria to humans that generally catalyze the transfer of gamma-phosphates of a nucleoside...; Region: NDPk_I; cd04413
553482005075	active site
553482005076	multimer interface [polypeptide binding]; other site
553482005077	HMMPfam hit to PF00334, Nucleoside diphosphate kinase, score 3.5e-58
553482005078	DNA/RNA non-specific endonuclease; Region: Endonuclea_NS_2; cl17626
553482005079	DNA/RNA non-specific endonuclease; Region: Endonuclease_NS; smart00892
553482005080	1 transmembrane helix predicted for SEQ1119 by TMHMM2.0 at aa 13-35
553482005081	HMMPfam hit to PF01223, DNA/RNA non-specific endonuclease, score 3.6e-28
553482005082	Predicted xylanase/chitin deacetylase [Carbohydrate transport and metabolism]; Region: CDA1; COG0726
553482005083	Putative catalytic NodB homology domain of PgaB, IcaB, and similar proteins which consist of a deformed (beta/alpha)8 barrel fold with 5- or 6-strands; Region: CE4_NodB_like_5s_6s; cd10918
553482005084	putative active site [active]
553482005085	putative metal binding site [ion binding]; other site
553482005086	HMMPfam hit to PF01522, Polysaccharide deacetylase, score 1.5e-38
553482005087	1 transmembrane helix predicted for SEQ1120 by TMHMM2.0 at aa 13-35
553482005088	homoserine dehydrogenase; Provisional; Region: PRK06349
553482005089	Homoserine dehydrogenase, NAD binding domain; Region: NAD_binding_3; pfam03447
553482005090	Homoserine dehydrogenase; Region: Homoserine_dh; pfam00742
553482005091	HMMPfam hit to PF03447, Homoserine dehydrogenase, NAD binding d, score 1.6e-24
553482005092	HMMPfam hit to PF00742, Homoserine dehydrogenase, score 3.2e-81
553482005093	PS01042 Homoserine dehydrogenase signature.
553482005094	homoserine kinase; Provisional; Region: PRK01212
553482005095	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
553482005096	HMMPfam hit to PF00288, GHMP kinases N terminal domain, score 1.2e-19
553482005097	PS00627 GHMP kinases ATP-binding domain.
553482005098	HMMPfam hit to PF08544, GHMP kinases C terminal, score 1e-08
553482005099	folylpolyglutamate synthase/dihydrofolate synthase; Region: folC; TIGR01499
553482005100	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
553482005101	HMMPfam hit to PF02875, Mur ligase family, glutamate ligase doma, score 0.021
553482005102	GTP cyclohydrolase I (GTP-CH-I) catalyzes the conversion of GTP into dihydroneopterin triphosphate.  The enzyme product is the precursor of tetrahydrofolate in eubacteria, fungi, and plants and of the folate analogs in methanogenic bacteria.  In...; Region: GTP_cyclohydro1; cd00642
553482005103	homodecamer interface [polypeptide binding]; other site
553482005104	GTP cyclohydrolase I; Provisional; Region: PLN03044
553482005105	active site
553482005106	putative catalytic site residues [active]
553482005107	zinc binding site [ion binding]; other site
553482005108	GTP-CH-I/GFRP interaction surface; other site
553482005109	HMMPfam hit to PF01227, GTP cyclohydrolase I, score 9.1e-54
553482005110	PS00859 GTP cyclohydrolase I signature 1.
553482005111	PS00860 GTP cyclohydrolase I signature 2.
553482005112	DHPS subgroup of Pterin binding enzymes. DHPS (dihydropteroate synthase), a functional homodimer, catalyzes the condensation of p-aminobenzoic acid (pABA) in the de novo biosynthesis of folate, which is an essential cofactor in both nucleic acid and...; Region: DHPS; cd00739
553482005113	dihydropteroate synthase; Region: DHPS; TIGR01496
553482005114	substrate binding pocket [chemical binding]; other site
553482005115	dimer interface [polypeptide binding]; other site
553482005116	inhibitor binding site; inhibition site
553482005117	PS00792 Dihydropteroate synthase signature 1.
553482005118	HMMPfam hit to PF00809, Pterin binding enzyme, score 5.2e-104
553482005119	PS00793 Dihydropteroate synthase signature 2.
553482005120	Dihydroneopterin aldolase (DHNA) and 7,8-dihydroneopterin triphosphate epimerase domain (DHNTPE); these enzymes have been designated folB and folX, respectively. Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and...; Region: DHNA_DHNTPE; cd00534
553482005121	homooctamer interface [polypeptide binding]; other site
553482005122	active site
553482005123	HMMPfam hit to PF02152, Dihydroneopterin aldolase, score 2.1e-43
553482005124	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK). Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and amino acids as well as formyl-tRNA. Mammalian cells are able to utilize pre-formed folates after...; Region: HPPK; cd00483
553482005125	catalytic center binding site [active]
553482005126	ATP binding site [chemical binding]; other site
553482005127	HMMPfam hit to PF01288, 7,8-dihydro-6-hydroxymethylpterin-pyrophosph, score 2.4e-65
553482005128	PS00794 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase signature.
553482005129	UDP-N-acetylenolpyruvoylglucosamine reductase; Provisional; Region: murB; PRK13905
553482005130	FAD binding domain; Region: FAD_binding_4; pfam01565
553482005131	UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain; Region: MurB_C; pfam02873
553482005132	HMMPfam hit to PF01565, FAD binding domain, score 4.3e-34
553482005133	HMMPfam hit to PF02873, UDP-N-acetylenolpyruvoylglucosamine red, score 2.3e-37
553482005134	ABC-type spermidine/putrescine transport systems, ATPase components [Amino acid transport and metabolism]; Region: PotA; COG3842
553482005135	ATP-binding cassette domain of the polyamine transporter; Region: ABC_PotA_N; cd03300
553482005136	Walker A/P-loop; other site
553482005137	ATP binding site [chemical binding]; other site
553482005138	Q-loop/lid; other site
553482005139	ABC transporter signature motif; other site
553482005140	Walker B; other site
553482005141	D-loop; other site
553482005142	H-loop/switch region; other site
553482005143	TOBE domain; Region: TOBE_2; pfam08402
553482005144	HMMPfam hit to PF00005, ABC transporter, score 8.5e-65
553482005145	PS00017 ATP/GTP-binding site motif A (P-loop).
553482005146	PS00211 ABC transporters family signature.
553482005147	HMMPfam hit to PF08402, TOBE domain, score 4.8e-08
553482005148	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
553482005149	dimer interface [polypeptide binding]; other site
553482005150	conserved gate region; other site
553482005151	putative PBP binding loops; other site
553482005152	ABC-ATPase subunit interface; other site
553482005153	6 transmembrane helices predicted for SEQ1130 by TMHMM2.0 at aa 7-29, 61-83, 90-112, 139-161, 202-224 and 239-258
553482005154	HMMPfam hit to PF00528, Binding-protein-dependent transport syst, score 0.0039
553482005155	ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177
553482005156	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
553482005157	dimer interface [polypeptide binding]; other site
553482005158	conserved gate region; other site
553482005159	putative PBP binding loops; other site
553482005160	ABC-ATPase subunit interface; other site
553482005161	7 transmembrane helices predicted for SEQ1131 by TMHMM2.0 at aa 7-29, 62-84, 97-119, 124-146, 174-193, 198-217 and 230-249
553482005162	HMMPfam hit to PF00528, Binding-protein-dependent transport syst, score 4.4e-11
553482005163	Spermidine/putrescine-binding periplasmic protein [Amino acid transport and metabolism]; Region: PotD; COG0687
553482005164	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; cl17199
553482005165	1 transmembrane helix predicted for SEQ1132 by TMHMM2.0 at aa 5-24
553482005166	HMMPfam hit to PF01547, Bacterial extracellular solute-binding prot, score 1.5e-15
553482005167	PS00017 ATP/GTP-binding site motif A (P-loop).
553482005168	ClC chloride channel EriC.  This domain is found in the EriC chloride transporters that mediate the extreme acid resistance response in eubacteria and archaea. This response allows bacteria to survive in the acidic environments by decarboxylation-linked...; Region: EriC; cd01031
553482005169	Chloride channel protein EriC [Inorganic ion transport and metabolism]; Region: EriC; COG0038
553482005170	Cl- selectivity filter; other site
553482005171	Cl- binding residues [ion binding]; other site
553482005172	pore gating glutamate residue; other site
553482005173	dimer interface [polypeptide binding]; other site
553482005174	H+/Cl- coupling transport residue; other site
553482005175	10 transmembrane helices predicted for SEQ1133 by TMHMM2.0 at aa 17-39, 59-78, 156-178, 191-213, 226-248, 268-288, 309-331, 335-354, 367-389 and 402-424
553482005176	HMMPfam hit to PF00654, Voltage gated chloride channel, score 4.1e-46
553482005177	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482005178	NnaC (CMP-NeuNAc synthetase) _like subfamily of SGNH_hydrolases, a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its...; Region: NnaC_like; cd01841
553482005179	active site
553482005180	catalytic triad [active]
553482005181	oxyanion hole [active]
553482005182	HMMPfam hit to PF00657, GDSL-like Lipase/Acylhydrolase, score 1.8e-07
553482005183	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; COG0628
553482005184	Domain of unknown function DUF20; Region: UPF0118; pfam01594
553482005185	8 transmembrane helices predicted for SEQ1135 by TMHMM2.0 at aa 17-34, 49-68, 88-110, 180-202, 248-270, 274-296, 305-327 and 342-364
553482005186	HMMPfam hit to PF01594, Domain of unknown function DUF20, score 1.2e-23
553482005187	hypothetical protein; Reviewed; Region: PRK00024
553482005188	Mov34/MPN/PAD-1 family; Region: MPN_DUF2466; cd08071
553482005189	MPN+ (JAMM) motif; other site
553482005190	Zinc-binding site [ion binding]; other site
553482005191	HMMPfam hit to PF04002, RadC, DNA repair protein, score 7e-68
553482005192	PS01302 DNA repair protein radC family signature.
553482005193	Predicted glutamine amidotransferases [General function prediction only]; Region: COG2071
553482005194	Subgroup of proteins having the Type 1 glutamine amidotransferase (GATase1) domain; Region: GATase1_2; cd01745
553482005195	catalytic triad [active]
553482005196	HMMPfam hit to PF00117, Glutamine amidotransferase class-I, score 2.1e-05
553482005197	HMMPfam hit to PF07722, Peptidase C26, score 1.2e-100
553482005198	AT-rich DNA-binding protein [General function prediction only]; Region: COG2344
553482005199	Putative DNA-binding protein N-terminus; Region: Put_DNA-bind_N; pfam06971
553482005200	CoA binding domain; Region: CoA_binding; pfam02629
553482005201	HMMPfam hit to PF02629, CoA binding domain, score 9.6e-33
553482005202	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482005203	HMMPfam hit to PF06971, DNA-binding protein N-terminu, score 8.2e-28
553482005204	Predicted helix-turn-helix motif with score 1210.000, SD 3.31 at aa 33-54, sequence ASSKQIADAMGIDSATVRRDFS
553482005205	Putative amino acid metabolism; Region: DUF1831; pfam08866
553482005206	Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes [Amino acid transport and metabolism]; Region: NifS; COG1104
553482005207	cysteine desulfurase NifS; Region: FeS_nifS; TIGR03402
553482005208	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
553482005209	catalytic residue [active]
553482005210	HMMPfam hit to PF00266, Aminotransferase class-V, score 1.5e-86
553482005211	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482005212	PS00729 AP endonucleases family 2 signature 1.
553482005213	HMMPfam hit to PF01212, Beta-eliminating lyase, score 7.8e-06
553482005214	PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site.
553482005215	ribose-phosphate pyrophosphokinase; Provisional; Region: PRK02458
553482005216	N-terminal domain of ribose phosphate pyrophosphokinase; Region: Pribosyltran_N; pfam13793
553482005217	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
553482005218	active site
553482005219	HMMPfam hit to PF00156, Phosphoribosyl transferase domain, score 3.4e-17
553482005220	Uncharacterized subgroup 1 of the CYTH-like superfamily; Region: CYTH-like_Pase_1; cd07762
553482005221	putative active site [active]
553482005222	putative metal binding residues [ion binding]; other site
553482005223	signature motif; other site
553482005224	putative triphosphate binding site [ion binding]; other site
553482005225	HMMPfam hit to PF01928, CYTH domain, score 2.6e-39
553482005226	Nucleotidyltransferase (NT) domain of RelA- and SpoT-like ppGpp synthetases and hydrolases; Region: NT_Rel-Spo_like; cd05399
553482005227	synthetase active site [active]
553482005228	NTP binding site [chemical binding]; other site
553482005229	metal binding site [ion binding]; metal-binding site
553482005230	HMMPfam hit to PF04607, Region found in RelA / SpoT proteins, score 9.6e-49
553482005231	inorganic polyphosphate/ATP-NAD kinase; Provisional; Region: ppnK; PRK04885
553482005232	ATP-NAD kinase; Region: NAD_kinase; pfam01513
553482005233	HMMPfam hit to PF01513, ATP-NAD kinase, score 1.8e-41
553482005234	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
553482005235	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
553482005236	active site
553482005237	HMMPfam hit to PF00849, RNA pseudouridylate synthase, score 9.4e-51
553482005238	PS01129 Rlu family of pseudouridine synthase signature.
553482005239	phosphotransacetylase; Reviewed; Region: eutD; PRK09653
553482005240	HMMPfam hit to PF01515, Phosphate acetyl/butaryl transferase, score 1.1e-163
553482005241	classical (c) SDR, subgroup 5; Region: SDR_c5; cd05346
553482005242	malonic semialdehyde reductase; Provisional; Region: PRK10538
553482005243	putative NAD(P) binding site [chemical binding]; other site
553482005244	homotetramer interface [polypeptide binding]; other site
553482005245	homodimer interface [polypeptide binding]; other site
553482005246	active site
553482005247	HMMPfam hit to PF00106, short chain dehydrogenase, score 4.5e-26
553482005248	HMMPfam hit to PF01370, NAD dependent epimerase/dehydratase family, score 0.00042
553482005249	PS00061 Short-chain dehydrogenases/reductases family signature.
553482005250	CDS contains a nonsense mutation (achre) after codon 172. Similar to Streptococcus pyogenes serotype M3 ABC transporter Prot:Q8K7I8 (EMBL:AE014074 (242 aa) fasta scores: E()=9.3e-68, 87.190% id in 242 aa
553482005251	HMMPfam hit to PF00005, ABC transporter, score 2.2e-18
553482005252	PS00017 ATP/GTP-binding site motif A (P-loop).
553482005253	PS00211 ABC transporters family signature.
553482005254	CDS contains a nonsense mutation (opal) after codon 198. Similar to Streptococcus pyogenes serotype M3 ABC transporter (binding protein) UniProt:Q8K7I7 (EMBL:AE014074 (508 aa) fasta scores: E()=5.7e-132, 81.102% id in 508 aa
553482005255	HMMPfam hit to PF00528, Binding-protein-dependent transport syst, score 1.1e-13
553482005256	5 transmembrane helices predicted for SEQ1151 by TMHMM2.0 at aa 23-45, 52-74, 78-97, 147-169 and 179-197
553482005257	PS00402 Binding-protein-dependent transport systems inner membrane comp. sign.
553482005258	HMMPfam hit to PF04069, Substrate binding domain of ABC-type glycine, score 1.5e-81
553482005259	guanosine 5'-monophosphate oxidoreductase; Provisional; Region: PRK05458
553482005260	IMPDH: The catalytic domain of the inosine monophosphate dehydrogenase. IMPDH catalyzes the NAD-dependent oxidation of inosine 5'-monophosphate (IMP) to xanthosine 5' monophosphate (XMP). It is a rate-limiting step in the de novo synthesis of...; Region: IMPDH; cd00381
553482005261	active site
553482005262	HMMPfam hit to PF00478, IMP dehydrogenase / GMP reductase domain, score 1.9e-148
553482005263	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
553482005264	active site
553482005265	HMMPfam hit to PF00156, Phosphoribosyl transferase domain, score 4.9e-17
553482005266	putative transposase OrfB; Reviewed; Region: PHA02517
553482005267	HTH-like domain; Region: HTH_21; pfam13276
553482005268	Integrase core domain; Region: rve; pfam00665
553482005269	Integrase core domain; Region: rve_2; pfam13333
553482005270	HMMPfam hit to PF00665, Integrase core domain, score 8.8e-38
553482005271	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
553482005272	Helix-turn-helix domain; Region: HTH_28; pfam13518
553482005273	HMMPfam hit to PF01527, Transposase, score 0.00062
553482005274	HMMPfam hit to PF02178, no description, score 0.21
553482005275	Predicted helix-turn-helix motif with score 1140.000, SD 3.07 at aa 19-40, sequence KSIKCLSEKFSIAESDLKYMIR
553482005276	4-oxalocrotonate tautomerase; Provisional; Region: PRK02289
553482005277	active site 1 [active]
553482005278	dimer interface [polypeptide binding]; other site
553482005279	hexamer interface [polypeptide binding]; other site
553482005280	active site 2 [active]
553482005281	HMMPfam hit to PF01361, Tautomerase enzyme, score 4.4e-26
553482005282	thymidine kinase; Provisional; Region: PRK04296
553482005283	HMMPfam hit to PF00265, Thymidine kinase, score 3.5e-67
553482005284	PS00017 ATP/GTP-binding site motif A (P-loop).
553482005285	PS00603 Thymidine kinase cellular-type signature.
553482005286	peptide chain release factor 1; Validated; Region: prfA; PRK00591
553482005287	This domain is found in peptide chain release factors; Region: PCRF; smart00937
553482005288	RF-1 domain; Region: RF-1; pfam00472
553482005289	HMMPfam hit to PF03462, PCRF domain, score 2e-64
553482005290	HMMPfam hit to PF00472, Peptidyl-tRNA hydrolase domain, score 9.5e-61
553482005291	N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase; Provisional; Region: PRK09328
553482005292	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
553482005293	S-adenosylmethionine binding site [chemical binding]; other site
553482005294	HMMPfam hit to PF05175, Methyltransferase small domain, score 5.9e-11
553482005295	HMMPfam hit to PF08242, Methyltransferase domain, score 4.6e-06
553482005296	HMMPfam hit to PF08241, Methyltransferase domain, score 0.00021
553482005297	PS00092 N-6 Adenine-specific DNA methylases signature.
553482005298	Putative translation factor (SUA5) [Translation, ribosomal structure and biogenesis]; Region: SUA5; COG0009
553482005299	HMMPfam hit to PF01300, yrdC domain, score 1.5e-37
553482005300	Acetyltransferases [General function prediction only]; Region: RimI; COG0456
553482005301	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
553482005302	Coenzyme A binding pocket [chemical binding]; other site
553482005303	HMMPfam hit to PF00583, Acetyltransferase (GNAT) family, score 2.4e-12
553482005304	serine hydroxymethyltransferase; Reviewed; Region: glyA; PRK00011
553482005305	Serine-glycine hydroxymethyltransferase (SHMT). This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). SHMT carries out interconversion of serine and glycine; it catalyzes the transfer of hydroxymethyl...; Region: SHMT; cd00378
553482005306	dimer interface [polypeptide binding]; other site
553482005307	active site
553482005308	glycine-pyridoxal phosphate binding site [chemical binding]; other site
553482005309	folate binding site [chemical binding]; other site
553482005310	HMMPfam hit to PF00464, Serine hydroxymethyltransferase, score 1.3e-229
553482005311	PS00096 Serine hydroxymethyltransferase pyridoxal-phosphate attachment site.
553482005312	37-kD nucleoid-associated bacterial protein; Region: NA37; cl15473
553482005313	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
553482005314	N-acetyl-D-glucosamine binding site [chemical binding]; other site
553482005315	catalytic residue [active]
553482005316	coenzyme A disulfide reductase; Reviewed; Region: PRK09564
553482005317	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
553482005318	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
553482005319	HMMPfam hit to PF07992, Pyridine nucleotide-disulphide oxidored, score 3.9e-45
553482005320	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482005321	HMMPfam hit to PF00070, Pyridine nucleotide-disulphide oxidored, score 3.9e-32
553482005322	HMMPfam hit to PF02852, Pyridine nucleotide-disulphide oxidored, score 3.3e-07
553482005323	L-lactate dehydrogenase; Reviewed; Region: ldh; PRK00066
553482005324	L-2-hydroxyisocapronate dehydrogenases and some bacterial L-lactate dehydrogenases; Region: HicDH_like; cd05291
553482005325	tetramer (dimer of dimers) interface [polypeptide binding]; other site
553482005326	NAD binding site [chemical binding]; other site
553482005327	dimer interface [polypeptide binding]; other site
553482005328	substrate binding site [chemical binding]; other site
553482005329	HMMPfam hit to PF02866, lactate/malate dehydrogenase, alpha/beta C-t, score 3.1e-77
553482005330	PS00064 L-lactate dehydrogenase active site.
553482005331	HMMPfam hit to PF00056, lactate/malate dehydrogenase, NAD binding do, score 3.2e-78
553482005332	DNA gyrase subunit A; Validated; Region: PRK05560
553482005333	DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes...; Region: TOP4c; cd00187
553482005334	CAP-like domain; other site
553482005335	active site
553482005336	primary dimer interface [polypeptide binding]; other site
553482005337	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
553482005338	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
553482005339	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
553482005340	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
553482005341	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
553482005342	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
553482005343	HMMPfam hit to PF00521, DNA gyrase/topoisomerase IV, subunit A, score 8e-304
553482005344	HMMPfam hit to PF03989, DNA gyrase C-terminal domain, beta-prop, score 1.5e-13
553482005345	HMMPfam hit to PF03989, DNA gyrase C-terminal domain, beta-prop, score 2.9e-17
553482005346	HMMPfam hit to PF03989, DNA gyrase C-terminal domain, beta-prop, score 5.2e-14
553482005347	HMMPfam hit to PF03989, DNA gyrase C-terminal domain, beta-prop, score 1.8e-13
553482005348	HMMPfam hit to PF03989, DNA gyrase C-terminal domain, beta-prop, score 2.9e-14
553482005349	HMMPfam hit to PF03989, DNA gyrase C-terminal domain, beta-prop, score 4.5e-12
553482005350	Sortase A (SrtA) or subfamily-1 sortases are cysteine transpeptidases found in gram-positive bacteria that anchor surface proteins to peptidoglycans of the bacterial cell wall envelope. They do so by catalyzing a transpeptidation reaction in which the...; Region: Sortase_A_1; cd06165
553482005351	active site
553482005352	catalytic site [active]
553482005353	1 transmembrane helix predicted for SEQ1171 by TMHMM2.0 at aa 4-21
553482005354	HMMPfam hit to PF04203, Sortase family, score 5.8e-55
553482005355	This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_1; cd08352
553482005356	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
553482005357	putative metal binding site [ion binding]; other site
553482005358	HMMPfam hit to PF00903, Glyoxalase/Bleomycin resistance protein/Di, score 5.2e-19
553482005359	PS00934 Glyoxalase I signature 1.
553482005360	Periplasmic solute binding protein family; Region: SBP_bac_9; pfam01297
553482005361	Helical backbone metal receptor (TroA-like domain). These proteins have been shown to function in the ABC transport of ferric siderophores and metal ions such as Mn2+, Fe3+, Cu2+ and/or Zn2+.  Their ligand binding site is formed in the interface between...; Region: TroA-like; cl00262
553482005362	intersubunit interface [polypeptide binding]; other site
553482005363	HMMPfam hit to PF01297, Periplasmic solute binding protein family, score 4.9e-76
553482005364	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482005365	streptococcal histidine triad protein; Region: strep_his_triad; TIGR01363
553482005366	Predicted secreted protein [Function unknown]; Region: COG4086
553482005367	Protein of unknown function (DUF1002); Region: DUF1002; pfam06207
553482005368	HMMPfam hit to PF06207, Protein of unknown function (DUF1002), score 4.5e-99
553482005369	FemAB family; Region: FemAB; pfam02388
553482005370	HMMPfam hit to PF02388, FemAB family, score 7.7e-20
553482005371	signal recognition particle protein; Provisional; Region: PRK10867
553482005372	SRP54-type protein, helical bundle domain; Region: SRP54_N; smart00963
553482005373	The signal recognition particle (SRP) mediates the transport to or across the plasma membrane in bacteria and the endoplasmic reticulum in eukaryotes. SRP recognizes N-terminal sighnal sequences of newly synthesized polypeptides at the ribosome. The...; Region: SRP; cd03115
553482005374	P loop; other site
553482005375	GTP binding site [chemical binding]; other site
553482005376	Signal peptide binding domain; Region: SRP_SPB; pfam02978
553482005377	HMMPfam hit to PF02978, Signal peptide binding domain, score 8.4e-55
553482005378	HMMPfam hit to PF00448, SRP54-type protein, GTPase domain, score 5.4e-119
553482005379	PS00300 SRP54-type proteins GTP-binding domain signature.
553482005380	PS00017 ATP/GTP-binding site motif A (P-loop).
553482005381	HMMPfam hit to PF02881, SRP54-type protein, helical bundle domain, score 1.1e-31
553482005382	Putative helix-turn-helix protein, YlxM / p13 like; Region: UPF0122; pfam04297
553482005383	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed...; Region: HTH_Hin_like; cd00569
553482005384	HMMPfam hit to PF04297, helix-turn-helix protein, YlxM, score 3.5e-60
553482005385	HMMPfam hit to PF04967, HTH DNA binding domain, score 0.00014
553482005386	HMMPfam hit to PF08281, Sigma-70, region, score 6.6e-05
553482005387	Predicted helix-turn-helix motif with score 1959.000, SD 5.86 at aa 36-57, sequence YSLAEIAEEFGVSRQAVYDNIK
553482005388	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
553482005389	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
553482005390	DNA-binding site [nucleotide binding]; DNA binding site
553482005391	UTRA domain; Region: UTRA; pfam07702
553482005392	HMMPfam hit to PF07702, UTRA domain, score 1.2e-46
553482005393	Predicted helix-turn-helix motif with score 1149.000, SD 3.10 at aa 161-182, sequence QTLTSNGYEIGKSQQTIYAKIA
553482005394	HMMPfam hit to PF00392, Bacterial regulatory proteins, gntR family, score 2.9e-23
553482005395	PS00043 Bacterial regulatory proteins, gntR family signature.
553482005396	Predicted helix-turn-helix motif with score 1494.000, SD 4.28 at aa 28-49, sequence PSERDLAEHFEVSRMTLRQAIT
553482005397	GMP synthase; Reviewed; Region: guaA; PRK00074
553482005398	Type 1 glutamine amidotransferase (GATase1) domain found in GMP synthetase; Region: GATase1_GMP_Synthase; cd01742
553482005399	AMP/PPi binding site [chemical binding]; other site
553482005400	candidate oxyanion hole; other site
553482005401	catalytic triad [active]
553482005402	potential glutamine specificity residues [chemical binding]; other site
553482005403	The C-terminal domain of GMP synthetase. It contains two subdomains; the ATP pyrophosphatase domain which closes to the N-termial and the dimerization domain at C-terminal end. The ATP-PPase is a twisted, five-stranded parallel beta-sheet sandwiched...; Region: GMP_synthase_C; cd01997
553482005404	ATP Binding subdomain [chemical binding]; other site
553482005405	Dimerization subdomain; other site
553482005406	HMMPfam hit to PF00117, Glutamine amidotransferase class-I, score 1.5e-55
553482005407	PS00442 Glutamine amidotransferases class-I active site.
553482005408	HMMPfam hit to PF00958, GMP synthase C terminal domain, score 5e-55
553482005409	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
553482005410	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
553482005411	non-specific DNA binding site [nucleotide binding]; other site
553482005412	salt bridge; other site
553482005413	sequence-specific DNA binding site [nucleotide binding]; other site
553482005414	Predicted transcriptional regulator [Transcription]; Region: COG2932
553482005415	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
553482005416	Catalytic site [active]
553482005417	HMMPfam hit to PF00717, Peptidase S24-like, score 1.9e-17
553482005418	HMMPfam hit to PF01381, Helix-turn-helix, score 3.5e-12
553482005419	Predicted helix-turn-helix motif with score 2505.000, SD 7.72 at aa 18-39, sequence ISQEQLGQLLGVNKMTISNWEK
553482005420	GtrA-like protein; Region: GtrA; pfam04138
553482005421	4 transmembrane helices predicted for SEQ1185 by TMHMM2.0 at aa 7-29, 34-56, 77-96 and 120-139
553482005422	HMMPfam hit to PF04138, GtrA-like protein, score 5.3e-15
553482005423	site-specific tyrosine recombinase XerS; Reviewed; Region: xerS; PRK05084
553482005424	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
553482005425	active site
553482005426	DNA binding site [nucleotide binding]
553482005427	Int/Topo IB signature motif; other site
553482005428	HMMPfam hit to PF00589, Phage integrase family, score 4.6e-13
553482005429	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
553482005430	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
553482005431	ATP binding site [chemical binding]; other site
553482005432	Mg2+ binding site [ion binding]; other site
553482005433	G-X-G motif; other site
553482005434	HMMPfam hit to PF02518, Histidine kinase-, DNA gyrase B-, and HSP90, score 9e-26
553482005435	2 transmembrane helices predicted for SEQ1187 by TMHMM2.0 at aa 9-31 and 35-57
553482005436	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
553482005437	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
553482005438	active site
553482005439	phosphorylation site [posttranslational modification]
553482005440	intermolecular recognition site; other site
553482005441	dimerization interface [polypeptide binding]; other site
553482005442	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
553482005443	DNA binding site [nucleotide binding]
553482005444	HMMPfam hit to PF00486, Transcriptional regulatory protein, C te, score 1.1e-20
553482005445	PS00339 Aminoacyl-transfer RNA synthetases class-II signature 2.
553482005446	HMMPfam hit to PF00072, Response regulator receiver domain, score 1.1e-19
553482005447	2 transmembrane helices predicted for SEQ1189 by TMHMM2.0 at aa 47-69 and 84-106
553482005448	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
553482005449	Helix-turn-helix domain; Region: HTH_28; pfam13518
553482005450	Predicted helix-turn-helix motif with score 1140.000, SD 3.07 at aa 19-40, sequence KSIKCLSEKFSIAESDLKYMIR
553482005451	HMMPfam hit to PF01527, Transposase, score 0.00062
553482005452	HMMPfam hit to PF02178, no description, score 0.21
553482005453	putative transposase OrfB; Reviewed; Region: PHA02517
553482005454	HTH-like domain; Region: HTH_21; pfam13276
553482005455	Integrase core domain; Region: rve; pfam00665
553482005456	Integrase core domain; Region: rve_2; pfam13333
553482005457	HMMPfam hit to PF00665, Integrase core domain, score 1.1e-37
553482005458	7 transmembrane helices predicted for SEQ1192 by TMHMM2.0 at aa 21-43, 53-75, 105-127, 147-169, 190-212, 222-244 and 280-302
553482005459	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
553482005460	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
553482005461	Walker A/P-loop; other site
553482005462	ATP binding site [chemical binding]; other site
553482005463	Q-loop/lid; other site
553482005464	ABC transporter signature motif; other site
553482005465	Walker B; other site
553482005466	D-loop; other site
553482005467	H-loop/switch region; other site
553482005468	HMMPfam hit to PF00005, ABC transporter, score 2.1e-62
553482005469	PS00211 ABC transporters family signature.
553482005470	PS00017 ATP/GTP-binding site motif A (P-loop).
553482005471	PASTA domain. This domain is found at the C-termini of several Penicillin-binding proteins (PBPs) and bacterial serine/threonine kinases. It is a small globular fold consisting of 3 beta-sheets and an alpha-helix. The name PASTA is derived from PBP and...; Region: PASTA; cl02768
553482005472	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3464
553482005473	Transposase; Region: DDE_Tnp_ISL3; pfam01610
553482005474	Predicted helix-turn-helix motif with score 1838.000, SD 5.45 at aa 119-140, sequence VSMTAIADRLSISTSTVMRKLN
553482005475	HMMPfam hit to PF01610, Transposase, score 2.7e-19
553482005476	oxaloacetate decarboxylase; Provisional; Region: PRK12331
553482005477	Pyruvate carboxylase and Transcarboxylase 5S, carboxyltransferase domain; Region: DRE_TIM_PC_TC_5S; cd07937
553482005478	active site
553482005479	catalytic residues [active]
553482005480	metal binding site [ion binding]; metal-binding site
553482005481	homodimer binding site [polypeptide binding]; other site
553482005482	HMMPfam hit to PF02436, Conserved carboxylase domain, score 2.3e-58
553482005483	HMMPfam hit to PF00682, HMGL-like, score 2.1e-46
553482005484	2'-(5''-triphosphoribosyl)-3'- dephospho-CoA:apo-citrate lyase; Reviewed; Region: citX; PRK01392
553482005485	HMMPfam hit to PF03802, Apo-citrate lyase phosphoribosyl-dephospho-C, score 6.7e-79
553482005486	Citrate lyase, alpha subunit [Energy production and conversion]; Region: CitF; COG3051
553482005487	Coenzyme A transferase; Region: CoA_trans; cl17247
553482005488	Acetyl-CoA hydrolase/transferase C-terminal domain; Region: AcetylCoA_hyd_C; pfam13336
553482005489	HMMPfam hit to PF04223, Citrate lyase, alpha subunit (CitF), score 0
553482005490	HpcH/HpaI aldolase/citrate lyase family; Region: HpcH_HpaI; cl17231
553482005491	HMMPfam hit to PF03328, HpcH/HpaI aldolase/citrate lyase family, score 2.1e-118
553482005492	citrate lyase subunit gamma; Provisional; Region: PRK13253
553482005493	HMMPfam hit to PF04953, Citrate lyase, gamma subunit, score 8.2e-63
553482005494	Oxaloacetate decarboxylase, gamma chain; Region: OAD_gamma; cl01458
553482005495	1 transmembrane helix predicted for SEQ1202 by TMHMM2.0 at aa 13-35
553482005496	Na+-transporting oxaloacetate decarboxylase beta subunit; Region: OAD_beta; pfam03977
553482005497	HMMPfam hit to PF03977, Na+-transporting methylmalonyl-CoA/oxaloacet, score 8.5e-263
553482005498	9 transmembrane helices predicted for SEQ1203 by TMHMM2.0 at aa 7-29, 39-61, 73-95, 105-127, 134-156, 166-187, 208-230, 281-303 and 345-367
553482005499	acetyl-CoA carboxylase biotin carboxyl carrier protein subunit; Validated; Region: PRK06549
553482005500	The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850
553482005501	carboxyltransferase (CT) interaction site; other site
553482005502	biotinylation site [posttranslational modification]; other site
553482005503	HMMPfam hit to PF00364, Biotin-requiring enzyme, score 4.5e-25
553482005504	PS00188 Biotin-requiring enzymes attachment site.
553482005505	H+/citrate symporter [Energy production and conversion]; Region: CitM; COG2851
553482005506	Citrate transporter; Region: CitMHS; pfam03600
553482005507	13 transmembrane helices predicted for SEQ1206 by TMHMM2.0 at aa 2-19, 24-46, 85-107, 122-153, 160-182, 197-219, 258-275, 280-299, 319-341, 356-375, 382-404, 409-431 and 443-465
553482005508	HMMPfam hit to PF03600, Citrate transporter, score 1.3e-136
553482005509	PS00211 ABC transporters family signature.
553482005510	Transcriptional regulators [Transcription]; Region: GntR; COG1802
553482005511	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
553482005512	DNA-binding site [nucleotide binding]; DNA binding site
553482005513	FCD domain; Region: FCD; pfam07729
553482005514	HMMPfam hit to PF00392, Bacterial regulatory proteins, gntR family, score 9.8e-07
553482005515	Predicted helix-turn-helix motif with score 1180.000, SD 3.21 at aa 43-64, sequence INEKEFSIALNISRTPIRYALG
553482005516	HMMPfam hit to PF07729, FCD domain, score 8.1e-05
553482005517	ATP:dephospho-CoA triphosphoribosyl transferase; Region: CitG; cl00768
553482005518	HMMPfam hit to PF01874, ATP:dephospho-CoA triphosphoribosyl transfer, score 5.8e-61
553482005519	PS00881 Protein splicing signature.
553482005520	CDS contains a frameshift at a polyA pentamer
553482005521	3 transmembrane helices predicted for SEQ1209 by TMHMM2.0 at aa 4-26, 63-85 and 125-147
553482005522	3 transmembrane helices predicted for SEQ1210 by TMHMM2.0 at aa 20-42, 82-104 and 137-159
553482005523	Citrate lyase synthetase [Energy production and conversion]; Region: CitC; COG3053
553482005524	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
553482005525	active site
553482005526	nucleotide binding site [chemical binding]; other site
553482005527	HIGH motif; other site
553482005528	KMSKS motif; other site
553482005529	HMMPfam hit to PF00583, Acetyltransferase (GNAT) family, score 5.1e-05
553482005530	HMMPfam hit to PF08218, Citrate lyase ligase C-terminal domain, score 1.8e-99
553482005531	putative transposase OrfB; Reviewed; Region: PHA02517
553482005532	HTH-like domain; Region: HTH_21; pfam13276
553482005533	Integrase core domain; Region: rve; pfam00665
553482005534	Integrase core domain; Region: rve_2; pfam13333
553482005535	HMMPfam hit to PF00665, Integrase core domain, score 1.1e-37
553482005536	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
553482005537	Helix-turn-helix domain; Region: HTH_28; pfam13518
553482005538	HMMPfam hit to PF01527, Transposase, score 0.00062
553482005539	HMMPfam hit to PF02178, no description, score 0.21
553482005540	Predicted helix-turn-helix motif with score 1140.000, SD 3.07 at aa 19-40, sequence KSIKCLSEKFSIAESDLKYMIR
553482005541	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3464
553482005542	Transposase; Region: DDE_Tnp_ISL3; pfam01610
553482005543	Predicted helix-turn-helix motif with score 1838.000, SD 5.45 at aa 119-140, sequence VSMTAIADRLSISTSTVMRKLN
553482005544	HMMPfam hit to PF01610, Transposase, score 2.7e-19
553482005545	tRNA (uracil-5-)-methyltransferase Gid; Reviewed; Region: PRK05335
553482005546	Glucose inhibited division protein A; Region: GIDA; pfam01134
553482005547	HMMPfam hit to PF01134, Glucose inhibited division protein A, score 3.5e-184
553482005548	PS01281 Glucose inhibited division protein A family signature 2.
553482005549	Protein of unknown function (DUF3307); Region: DUF3307; pfam11750
553482005550	5 transmembrane helices predicted for SEQ1217 by TMHMM2.0 at aa 52-74, 95-114, 129-151, 178-197 and 212-234
553482005551	DNA topoisomerase I; Validated; Region: PRK05582
553482005552	TOPRIM_TopoIA_TopoI: The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to Escherichia coli DNA topoisomerase I.   Type IA DNA topoisomerases remove (relax) negative supercoils in the...; Region: TOPRIM_TopoIA_TopoI; cd03363
553482005553	active site
553482005554	interdomain interaction site; other site
553482005555	putative metal-binding site [ion binding]; other site
553482005556	nucleotide binding site [chemical binding]; other site
553482005557	DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cd00186
553482005558	domain I; other site
553482005559	DNA binding groove [nucleotide binding]
553482005560	phosphate binding site [ion binding]; other site
553482005561	domain II; other site
553482005562	domain III; other site
553482005563	nucleotide binding site [chemical binding]; other site
553482005564	catalytic site [active]
553482005565	domain IV; other site
553482005566	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
553482005567	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
553482005568	HMMPfam hit to PF01396, Topoisomerase DNA binding C4 zinc fing, score 3.8e-14
553482005569	HMMPfam hit to PF01396, Topoisomerase DNA binding C4 zinc fing, score 2.1e-15
553482005570	HMMPfam hit to PF01131, DNA topoisomerase, score 6.4e-170
553482005571	PS00396 Prokaryotic DNA topoisomerase I active site.
553482005572	HMMPfam hit to PF01751, Toprim domain, score 1.5e-33
553482005573	DNA recombination-mediator protein A; Region: DNA_processg_A; pfam02481
553482005574	DNA protecting protein DprA; Region: dprA; TIGR00732
553482005575	HMMPfam hit to PF02481, SMF family, score 6.3e-83
553482005576	bacterial Ribonuclease HII-like; Region: RNase_HII_bacteria_HII_like; cd07182
553482005577	RNA/DNA hybrid binding site [nucleotide binding]; other site
553482005578	active site
553482005579	HMMPfam hit to PF01351, Ribonuclease HII, score 1.2e-71
553482005580	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482005581	GTPase YlqF; Reviewed; Region: rbgA; PRK09563
553482005582	Circularly permuted YlqF GTPase; Region: YlqF; cd01856
553482005583	GTP/Mg2+ binding site [chemical binding]; other site
553482005584	G4 box; other site
553482005585	G5 box; other site
553482005586	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cl17170
553482005587	G1 box; other site
553482005588	G1 box; other site
553482005589	GTP/Mg2+ binding site [chemical binding]; other site
553482005590	Switch I region; other site
553482005591	G2 box; other site
553482005592	G2 box; other site
553482005593	G3 box; other site
553482005594	G3 box; other site
553482005595	Switch II region; other site
553482005596	Switch II region; other site
553482005597	G4 box; other site
553482005598	G5 box; other site
553482005599	HMMPfam hit to PF01926, GTPase of unknown function, score 1.3e-19
553482005600	PS00017 ATP/GTP-binding site motif A (P-loop).
553482005601	CDS contains a nonsense mutation (amber) after codon 138. Similar to Streptococcus pneumoniae ABC transporter, ATP-binding protein UniProt:Q97NR1 (EMBL:AE005672 (210 aa) fasta scores: E()=1.7e-55, 89.048% id in 210 aa
553482005602	Predicted helix-turn-helix motif with score 1005.000, SD 2.61 at aa 96-117, sequence LKLGLIGQKLNKSEQTMRQKQA
553482005603	PS00017 ATP/GTP-binding site motif A (P-loop).
553482005604	gene remnant. Similar to the C-terminal region of Streptococcus pneumoniae hypothetical protein UniProt:Q9ZHB2 (EMBL:AF068902 (493 aa) fasta scores: E()=1.1e-36, 42.014% id in 288 aa
553482005605	HMMPfam hit to PF07242, Protein of unknown function (DUF1430), score 1.2e-43
553482005606	3 transmembrane helices predicted for SEQ1225 by TMHMM2.0 at aa 185-207, 227-249 and 253-273
553482005607	gene remnant; Similar to internal region of S. zooepidemicus protein SZO09950
553482005608	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
553482005609	Helix-turn-helix domain; Region: HTH_28; pfam13518
553482005610	Predicted helix-turn-helix motif with score 1140.000, SD 3.07 at aa 19-40, sequence KSIKCLSEKFSIAESDLKYMIR
553482005611	HMMPfam hit to PF01527, Transposase, score 0.00062
553482005612	HMMPfam hit to PF02178, no description, score 0.21
553482005613	putative transposase OrfB; Reviewed; Region: PHA02517
553482005614	HTH-like domain; Region: HTH_21; pfam13276
553482005615	Integrase core domain; Region: rve; pfam00665
553482005616	Integrase core domain; Region: rve_2; pfam13333
553482005617	HMMPfam hit to PF00665, Integrase core domain, score 1.1e-37
553482005618	Site-specific recombinases, DNA invertase Pin homologs [DNA replication, recombination, and repair]; Region: PinR; COG1961
553482005619	Serine Recombinase family, catalytic domain; a DNA binding domain may be present either N- or C-terminal to the catalytic domain. These enzymes perform site-specific recombination of DNA molecules by a concerted, four-strand cleavage and rejoining...; Region: Ser_Recombinase; cl02788
553482005620	catalytic residues [active]
553482005621	catalytic nucleophile [active]
553482005622	Recombinase; Region: Recombinase; pfam07508
553482005623	HMMPfam hit to PF07508, Recombinase, score 1.1e-16
553482005624	ICESe2
553482005625	PS00017 ATP/GTP-binding site motif A (P-loop).
553482005626	HMMPfam hit to PF00239, Resolvase, N terminal domain, score 0.00013
553482005627	RNA polymerase sigma factor, sigma-70 family; Region: sigma70-ECF; TIGR02937
553482005628	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
553482005629	DNA binding residues [nucleotide binding]
553482005630	HMMPfam hit to PF04545, Sigma-70, region, score 5.8e-08
553482005631	HMMPfam hit to PF08281, Sigma-70, region, score 0.0027
553482005632	Predicted helix-turn-helix motif with score 1283.000, SD 3.56 at aa 100-121, sequence KTLTEVAKQRDTNPMKISRLRN
553482005633	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
553482005634	Q-loop/lid; other site
553482005635	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
553482005636	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
553482005637	methyl indole-3-acetate methyltransferase; Region: PLN02211; cl17657
553482005638	PS00120 Lipases, serine active site.
553482005639	1 transmembrane helix predicted for SEQ1233 by TMHMM2.0 at aa 5-27
553482005640	Saccharopine dehydrogenase; Region: Saccharop_dh; pfam03435
553482005641	HMMPfam hit to PF03435, Saccharopine dehydrogenase, score 0.00022
553482005642	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
553482005643	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
553482005644	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
553482005645	Walker A/P-loop; other site
553482005646	ATP binding site [chemical binding]; other site
553482005647	Q-loop/lid; other site
553482005648	ABC transporter signature motif; other site
553482005649	Walker B; other site
553482005650	D-loop; other site
553482005651	H-loop/switch region; other site
553482005652	HMMPfam hit to PF00005, ABC transporter, score 5.3e-59
553482005653	PS00211 ABC transporters family signature.
553482005654	PS00017 ATP/GTP-binding site motif A (P-loop).
553482005655	HMMPfam hit to PF00664, ABC transporter transmembrane region, score 2e-05
553482005656	6 transmembrane helices predicted for SEQ1235 by TMHMM2.0 at aa 21-43, 63-85, 143-161, 165-183, 251-273 and 277-296
553482005657	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
553482005658	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
553482005659	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
553482005660	Walker A/P-loop; other site
553482005661	ATP binding site [chemical binding]; other site
553482005662	Q-loop/lid; other site
553482005663	ABC transporter signature motif; other site
553482005664	Walker B; other site
553482005665	D-loop; other site
553482005666	H-loop/switch region; other site
553482005667	HMMPfam hit to PF00005, ABC transporter, score 1.1e-57
553482005668	PS00211 ABC transporters family signature.
553482005669	PS00017 ATP/GTP-binding site motif A (P-loop).
553482005670	5 transmembrane helices predicted for SEQ1236 by TMHMM2.0 at aa 21-43, 58-80, 142-164, 250-272 and 279-296
553482005671	HMMPfam hit to PF00664, ABC transporter transmembrane region, score 4.8e-12
553482005672	ABC-type cobalt transport system, ATPase component [Inorganic ion transport and metabolism]; Region: CbiO; COG1122
553482005673	First domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain1; cd03225
553482005674	Walker A/P-loop; other site
553482005675	ATP binding site [chemical binding]; other site
553482005676	Q-loop/lid; other site
553482005677	ABC transporter signature motif; other site
553482005678	Walker B; other site
553482005679	D-loop; other site
553482005680	H-loop/switch region; other site
553482005681	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
553482005682	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
553482005683	Walker A/P-loop; other site
553482005684	ATP binding site [chemical binding]; other site
553482005685	Q-loop/lid; other site
553482005686	ABC transporter signature motif; other site
553482005687	Walker B; other site
553482005688	D-loop; other site
553482005689	H-loop/switch region; other site
553482005690	HMMPfam hit to PF00005, ABC transporter, score 1.8e-41
553482005691	PS00211 ABC transporters family signature.
553482005692	PS00017 ATP/GTP-binding site motif A (P-loop).
553482005693	HMMPfam hit to PF00005, ABC transporter, score 6.2e-39
553482005694	PS00017 ATP/GTP-binding site motif A (P-loop).
553482005695	ABC-type cobalt transport system, permease component CbiQ and related transporters [Inorganic ion transport and metabolism]; Region: CbiQ; COG0619
553482005696	HMMPfam hit to PF02361, Cobalt transport protein, score 0.00031
553482005697	3 transmembrane helices predicted for SEQ1238 by TMHMM2.0 at aa 15-37, 49-71 and 81-103
553482005698	Hypothetical bacterial integral membrane protein (Trep_Strep); Region: Trep_Strep; pfam09605
553482005699	6 transmembrane helices predicted for SEQ1239 by TMHMM2.0 at aa 12-29, 33-55, 62-79, 84-103, 110-132 and 159-181
553482005700	Condensation domain; Region: Condensation; pfam00668
553482005701	Non-ribosomal peptide synthetase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: EntF; COG1020
553482005702	Nonribosomal peptide synthase; Region: NRPS; pfam08415
553482005703	Methyltransferase domain; Region: Methyltransf_12; pfam08242
553482005704	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
553482005705	HMMPfam hit to PF00550, Phosphopantetheine attachment site, score 0.00013
553482005706	HMMPfam hit to PF08241, Methyltransferase domain, score 0.0019
553482005707	HMMPfam hit to PF08242, Methyltransferase domain, score 8.6e-10
553482005708	HMMPfam hit to PF08415, Nonribosomal peptide synthase, score 5.4e-06
553482005709	HMMPfam hit to PF00668, Condensation domain, score 2e-12
553482005710	Oxidoreductase (NAD-binding), involved in siderophore biosynthesis [Secondary metabolites biosynthesis, transport, and catabolism]; Region: PchG; COG4693
553482005711	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
553482005712	Methyltransferase domain; Region: Methyltransf_23; pfam13489
553482005713	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
553482005714	S-adenosylmethionine binding site [chemical binding]; other site
553482005715	HMMPfam hit to PF08241, Methyltransferase domain, score 6.5e-07
553482005716	HMMPfam hit to PF08242, Methyltransferase domain, score 1.2e-18
553482005717	HMMPfam hit to PF01408, Oxidoreductase family, NAD-binding Ro, score 1.3e-22
553482005718	Aryl carrier domain [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG3433
553482005719	Condensation domain; Region: Condensation; pfam00668
553482005720	Non-ribosomal peptide synthetase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: EntF; COG1020
553482005721	Nonribosomal peptide synthase; Region: NRPS; pfam08415
553482005722	The adenylation domain of nonribosomal peptide synthetases (NRPS), including Streptoalloteichus tallysomycin biosynthesis genes; Region: A_NRPS_TlmIV_like; cd12114
553482005723	acyl-activating enzyme (AAE) consensus motif; other site
553482005724	AMP binding site [chemical binding]; other site
553482005725	Methyltransferase domain; Region: Methyltransf_12; pfam08242
553482005726	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
553482005727	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
553482005728	Condensation domain; Region: Condensation; pfam00668
553482005729	Non-ribosomal peptide synthetase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: EntF; COG1020
553482005730	Nonribosomal peptide synthase; Region: NRPS; pfam08415
553482005731	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
553482005732	HMMPfam hit to PF00550, Phosphopantetheine attachment site, score 4.7e-10
553482005733	PS00012 Phosphopantetheine attachment site.
553482005734	HMMPfam hit to PF08415, Nonribosomal peptide synthase, score 5e-16
553482005735	HMMPfam hit to PF00668, Condensation domain, score 1.3e-33
553482005736	HMMPfam hit to PF00550, Phosphopantetheine attachment site, score 2.8e-10
553482005737	PS00455 AMP-binding domain signature.
553482005738	HMMPfam hit to PF08415, Nonribosomal peptide synthase, score 1.1e-14
553482005739	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482005740	HMMPfam hit to PF00668, Condensation domain, score 4.5e-43
553482005741	2,3-dihydroxybenzoate-AMP ligase; Region: 23DHB-AMP_lg; cd05920
553482005742	Peptide arylation enzymes [Secondary metabolites biosynthesis, transport, and catabolism]; Region: EntE; COG1021
553482005743	acyl-activating enzyme (AAE) consensus motif; other site
553482005744	active site
553482005745	AMP binding site [chemical binding]; other site
553482005746	substrate binding site [chemical binding]; other site
553482005747	HMMPfam hit to PF00501, AMP-binding enzyme, score 2.2e-86
553482005748	PS00455 AMP-binding domain signature.
553482005749	Phosphopantetheinyl transferase [Coenzyme metabolism]; Region: Sfp; COG2091
553482005750	4'-phosphopantetheinyl transferase superfamily; Region: ACPS; pfam01648
553482005751	HMMPfam hit to PF01648, 4'-phosphopantetheinyl transferase superfami, score 8.5e-06
553482005752	Predicted thioesterase involved in non-ribosomal peptide biosynthesis [Secondary metabolites biosynthesis, transport, and catabolism]; Region: GrsT; COG3208
553482005753	HMMPfam hit to PF00975, Thioesterase domain, score 7.2e-43
553482005754	Iron dependent repressor, N-terminal DNA binding domain; Region: Fe_dep_repress; pfam01325
553482005755	Helix-turn-helix diphteria tox regulatory element; Region: HTH_DTXR; smart00529
553482005756	Iron dependent repressor, metal binding and dimerisation domain; Region: Fe_dep_repr_C; pfam02742
553482005757	HMMPfam hit to PF01047, MarR family, score 0.0022
553482005758	HMMPfam hit to PF01325, Iron dependent repressor, N-terminal D, score 4.8e-07
553482005759	Predicted helix-turn-helix motif with score 1163.000, SD 3.15 at aa 28-49, sequence VRNIDIVDKLGVARATVTHMLR
553482005760	1 transmembrane helix predicted for SEQ1247 by TMHMM2.0 at aa 20-42
553482005761	Relaxase/Mobilisation nuclease domain; Region: Relaxase; pfam03432
553482005762	HMMPfam hit to PF03432, Relaxase/Mobilisation nuclease domain, score 5.6e-44
553482005763	4 transmembrane helices predicted for SEQ1251 by TMHMM2.0 at aa 5-27, 58-80, 93-115 and 130-148
553482005764	Replication protein A, class 2b aminoacyl-tRNA synthetases, and related proteins with oligonucleotide/oligosaccharide (OB) fold; Region: RPA_2b-aaRSs_OBF_like; cl09930
553482005765	generic binding surface II; other site
553482005766	generic binding surface I; other site
553482005767	HMMPfam hit to PF00436, Single-strand binding protein family, score 0.0087
553482005768	Uncharacterized conserved protein [Function unknown]; Region: COG4983
553482005769	Methyltransferase domain; Region: Methyltransf_26; pfam13659
553482005770	DNA methylase [Transcription / DNA replication, recombination, and repair]; Region: COG4646
553482005771	SNF2 family N-terminal domain; Region: SNF2_N; pfam00176
553482005772	DNA methylase [Transcription / DNA replication, recombination, and repair]; Region: COG4646
553482005773	Superfamily II DNA/RNA helicases, SNF2 family [Transcription / DNA replication, recombination, and repair]; Region: HepA; COG0553
553482005774	nucleotide binding region [chemical binding]; other site
553482005775	helicase superfamily c-terminal domain; Region: HELICc; smart00490
553482005776	ATP-binding site [chemical binding]; other site
553482005777	HMMPfam hit to PF00271, Helicase conserved C-terminal domain, score 0.0011
553482005778	HMMPfam hit to PF02384, N-6 DNA Methylase, score 0.00028
553482005779	PS00038 Myc-type, 'helix-loop-helix' dimerization domain signature.
553482005780	PS00092 N-6 Adenine-specific DNA methylases signature.
553482005781	DNA topoisomerase III; Provisional; Region: PRK07726
553482005782	TOPRIM_TopoIA_TopoIII: The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to topoisomerase III. Type IA DNA topoisomerases remove (relax) negative supercoils in the DNA by: cleaving...; Region: TOPRIM_TopoIA_TopoIII; cd03362
553482005783	active site
553482005784	putative interdomain interaction site [polypeptide binding]; other site
553482005785	putative metal-binding site [ion binding]; other site
553482005786	putative nucleotide binding site [chemical binding]; other site
553482005787	DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cd00186
553482005788	domain I; other site
553482005789	DNA binding groove [nucleotide binding]
553482005790	phosphate binding site [ion binding]; other site
553482005791	domain II; other site
553482005792	domain III; other site
553482005793	nucleotide binding site [chemical binding]; other site
553482005794	catalytic site [active]
553482005795	domain IV; other site
553482005796	HMMPfam hit to PF01131, DNA topoisomerase, score 2.7e-95
553482005797	PS00396 Prokaryotic DNA topoisomerase I active site.
553482005798	HMMPfam hit to PF01751, Toprim domain, score 2.7e-21
553482005799	Nucleotidyl transferase of unknown function (DUF1814); Region: DUF1814; pfam08843
553482005800	Predicted helix-turn-helix motif with score 1063.000, SD 2.81 at aa 228-249, sequence GKIIDLLEKLKINEAFLKRWQA
553482005801	Domain of unknown function (DUF4095); Region: DUF4095; pfam13338
553482005802	Domain of unknown function (DUF4366); Region: DUF4366; pfam14283
553482005803	2 transmembrane helices predicted for SEQ1259 by TMHMM2.0 at aa 5-27 and 453-475
553482005804	1 transmembrane helix predicted for SEQ1261 by TMHMM2.0 at aa 415-437
553482005805	PS00018 EF-hand calcium-binding domain.
553482005806	DNA modification methylase [DNA replication, recombination, and repair]; Region: COG0863
553482005807	DNA methylase; Region: N6_N4_Mtase; pfam01555
553482005808	HMMPfam hit to PF01555, DNA methylase, score 1.1e-67
553482005809	PS00093 N-4 cytosine-specific DNA methylases signature.
553482005810	AAA-like domain; Region: AAA_10; pfam12846
553482005811	Predicted helix-turn-helix motif with score 1355.000, SD 3.80 at aa 744-765, sequence TDRDILAKKLNISKHQLSYVTN
553482005812	PS00017 ATP/GTP-binding site motif A (P-loop).
553482005813	PrgI family protein; Region: PrgI; pfam12666
553482005814	2 transmembrane helices predicted for SEQ1264 by TMHMM2.0 at aa 26-43 and 47-69
553482005815	1 transmembrane helix predicted for SEQ1265 by TMHMM2.0 at aa 13-32
553482005816	5 transmembrane helices predicted for SEQ1266 by TMHMM2.0 at aa 49-71, 92-109, 168-190, 210-232 and 242-264
553482005817	Maff2 family; Region: Maff2; pfam12750
553482005818	2 transmembrane helices predicted for SEQ1267 by TMHMM2.0 at aa 7-28 and 48-70
553482005819	1 transmembrane helix predicted for SEQ1268 by TMHMM2.0 at aa 5-24
553482005820	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
553482005821	putative bacteriocin export ABC transporter, lactococcin 972 group; Region: L_ocin_972_ABC; TIGR03608
553482005822	Walker A/P-loop; other site
553482005823	ATP binding site [chemical binding]; other site
553482005824	Q-loop/lid; other site
553482005825	ABC transporter signature motif; other site
553482005826	Walker B; other site
553482005827	D-loop; other site
553482005828	H-loop/switch region; other site
553482005829	HMMPfam hit to PF00005, ABC transporter, score 5.9e-43
553482005830	PS00211 ABC transporters family signature.
553482005831	PS00017 ATP/GTP-binding site motif A (P-loop).
553482005832	bacteriocin-associated integral membrane (putative immunity) protein; Region: bact_immun_7tm; TIGR01654
553482005833	8 transmembrane helices predicted for SEQ1270 by TMHMM2.0 at aa 7-29, 188-210, 236-258, 273-295, 316-338, 593-611, 648-670 and 685-707
553482005834	Bacteriocin (Lactococcin_972); Region: Lactococcin_972; cl09891
553482005835	gene remnant. Similar to the C-terminal region of Enterococcus faecalis VanSG UniProt:Q9KHM2 (EMBL:AF253562 (367 aa) fasta scores: E()=3.5e-12, 31.841% id in 201 aa
553482005836	HMMPfam hit to PF02518, Histidine kinase-, DNA gyrase B-, and HSP90, score 8.2e-12
553482005837	Similar to the N-terminal region of Geobacter uraniumreducens RF4 hypothetical protein UniProt:Q2DIN1 (EMBL:AAON01000083 (285 aa) fasta scores: E()=4.2e-39, 55.251% id in 219 aa. CDS is truncated by the insertion of the downstream conjugative transposon and IS element
553482005838	Stage 0 sporulation protein J (antagonist of Soj) containing ParB-like nuclease domain [Transcription]; Region: Spo0J; COG1475
553482005839	ParB-like nuclease domain; Region: ParB; smart00470
553482005840	Predicted helix-turn-helix motif with score 1106.000, SD 2.95 at aa 176-197, sequence DSRKTLGKEYNLSGASIARYLR
553482005841	HMMPfam hit to PF02195, ParB-like nuclease domain, score 7.6e-15
553482005842	ATPases involved in chromosome partitioning [Cell division and chromosome partitioning]; Region: Soj; COG1192
553482005843	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
553482005844	P-loop; other site
553482005845	Magnesium ion binding site [ion binding]; other site
553482005846	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
553482005847	Magnesium ion binding site [ion binding]; other site
553482005848	HMMPfam hit to PF01656, CobQ/CobB/MinD/ParA nucleotide binding domai, score 1.8e-52
553482005849	gene remnant. CDS is truncated by recombination event. C-terminal region of the this CDS is SEQ1103. Similar to the N-terminal region of bacillus thuringiensis serovar israelensis multidrug/protein/lipid ABC transporter family, ATP-binding permease protein UniProt:Q3ER17 (EMBL:AAJM01000217 (588 aa) fasta scores: E()=9.9e-30, 30.179% id in 391 aa
553482005850	HMMPfam hit to PF00664, ABC transporter transmembrane region, score 1.7e-20
553482005851	4 transmembrane helices predicted for SEQ1276 by TMHMM2.0 at aa 13-35, 64-83, 139-161 and 166-183
553482005852	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
553482005853	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
553482005854	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
553482005855	Walker A/P-loop; other site
553482005856	ATP binding site [chemical binding]; other site
553482005857	Q-loop/lid; other site
553482005858	ABC transporter signature motif; other site
553482005859	Walker B; other site
553482005860	D-loop; other site
553482005861	H-loop/switch region; other site
553482005862	HMMPfam hit to PF00005, ABC transporter, score 4.7e-54
553482005863	PS00211 ABC transporters family signature.
553482005864	PS00017 ATP/GTP-binding site motif A (P-loop).
553482005865	6 transmembrane helices predicted for SEQ1277 by TMHMM2.0 at aa 13-35, 55-77, 124-146, 151-173, 239-261 and 276-298
553482005866	HMMPfam hit to PF00664, ABC transporter transmembrane region, score 1.2e-21
553482005867	5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases [Nucleotide transport and metabolism]; Region: UshA; COG0737
553482005868	Bacillus subtilis YhcR endonuclease and related proteins, N-terminal metallophosphatase domain; Region: MPP_YhcR_N; cd07412
553482005869	putative active site [active]
553482005870	putative metal binding site [ion binding]; other site
553482005871	5'-nucleotidase, C-terminal domain; Region: 5_nucleotid_C; pfam02872
553482005872	1 transmembrane helix predicted for SEQ1278 by TMHMM2.0 at aa 5-27
553482005873	HMMPfam hit to PF00149, Calcineurin-like phosphoesterase, score 6e-09
553482005874	PS00786 5'-nucleotidase signature 2.
553482005875	HMMPfam hit to PF02872, 5'-nucleotidase, C-terminal domain, score 9e-49
553482005876	PS00343 Gram-positive cocci surface proteins 'anchoring' hexapeptide.
553482005877	Polypeptide or peptide deformylase; a family of metalloenzymes that catalyzes the removal of the N-terminal formyl group in a growing polypeptide chain following translation initiation during protein synthesis in prokaryotes. These enzymes utilize Fe(II)...; Region: Pep_deformylase; cd00487
553482005878	active site
553482005879	catalytic residues [active]
553482005880	metal binding site [ion binding]; metal-binding site
553482005881	HMMPfam hit to PF01327, Polypeptide deformylase, score 5.3e-11
553482005882	glutamate dehydrogenase; Provisional; Region: PRK09414
553482005883	Glu/Leu/Phe/Val dehydrogenase, dimerisation domain; Region: ELFV_dehydrog_N; pfam02812
553482005884	NAD(P) binding domain of glutamate dehydrogenase, subgroup 2; Region: NAD_bind_2_Glu_DH; cd05313
553482005885	NAD(P) binding site [chemical binding]; other site
553482005886	HMMPfam hit to PF00208, Glutamate/Leucine/Phenylalanine/Valin, score 3.4e-132
553482005887	PS00017 ATP/GTP-binding site motif A (P-loop).
553482005888	HMMPfam hit to PF02812, Glu/Leu/Phe/Val dehydrogenase, dimeri, score 4.8e-85
553482005889	CDS contains a frameshift after codon 288, due to the insertion of 4 nucleotides. Similar to Streptococcus agalactiae ABC transporter, ATP-binding/permease protein UniProt:Q3D0Y9 (EMBL:AAJS01000036 (589 aa) fasta scores: E()=4.1e-132, 76.061% id in 589 aa
553482005890	HMMPfam hit to PF00005, ABC transporter, score 3.5e-60
553482005891	PS00211 ABC transporters family signature.
553482005892	PS00017 ATP/GTP-binding site motif A (P-loop).
553482005893	PS00039 DEAD-box subfamily ATP-dependent helicases signature.
553482005894	HMMPfam hit to PF00664, ABC transporter transmembrane region, score 2.6e-34
553482005895	5 transmembrane helices predicted for SEQ1282 by TMHMM2.0 at aa 20-42, 62-84, 152-169, 173-192 and 260-282
553482005896	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
553482005897	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
553482005898	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
553482005899	Walker A/P-loop; other site
553482005900	ATP binding site [chemical binding]; other site
553482005901	Q-loop/lid; other site
553482005902	ABC transporter signature motif; other site
553482005903	Walker B; other site
553482005904	D-loop; other site
553482005905	H-loop/switch region; other site
553482005906	HMMPfam hit to PF00005, ABC transporter, score 5e-52
553482005907	PS00211 ABC transporters family signature.
553482005908	PS00017 ATP/GTP-binding site motif A (P-loop).
553482005909	6 transmembrane helices predicted for SEQ1283 by TMHMM2.0 at aa 20-37, 52-74, 129-151, 156-175, 237-259 and 274-296
553482005910	HMMPfam hit to PF00664, ABC transporter transmembrane region, score 5.4e-30
553482005911	CDS contains a frameshift after codon 442. Frameshift occurs at a poly A hexamer. Similar to Streptococcus pyogenes serotype M3 ABC transporter ATP-binding protein Uup UniProt:Q1JHD9 (EMBL:CP000260 (625 aa) fasta scores: E()=3.2e-115, 78.115% id in 626 aa
553482005912	PS00017 ATP/GTP-binding site motif A (P-loop).
553482005913	HMMPfam hit to PF00005, ABC transporter, score 5.8e-39
553482005914	PS00211 ABC transporters family signature.
553482005915	PS00017 ATP/GTP-binding site motif A (P-loop).
553482005916	tRNA CCA-pyrophosphorylase; Provisional; Region: PRK13299
553482005917	Nucleotidyltransferase (NT) domain of ClassII CCA-adding enzymes; Region: NT_ClassII-CCAase; cd05398
553482005918	active site
553482005919	NTP binding site [chemical binding]; other site
553482005920	metal binding triad [ion binding]; metal-binding site
553482005921	Probable RNA and SrmB- binding site of polymerase A; Region: PolyA_pol_RNAbd; pfam12627
553482005922	tRNA nucleotidyltransferase domain 2 putative; Region: tRNA_NucTran2_2; pfam13735
553482005923	HMMPfam hit to PF01743, Poly A polymerase family, score 5e-58
553482005924	EDD domain protein, DegV family; Region: DegV; TIGR00762
553482005925	Uncharacterized protein, DegV family COG1307; Region: DegV; pfam02645
553482005926	HMMPfam hit to PF02645, Uncharacterized protein, DegV family COG1307, score 1e-76
553482005927	Protein of unknown function (DUF1149); Region: DUF1149; pfam06619
553482005928	HMMPfam hit to PF06619, Protein of unknown function (DUF1149), score 5.8e-95
553482005929	putative transposase OrfB; Reviewed; Region: PHA02517
553482005930	HTH-like domain; Region: HTH_21; pfam13276
553482005931	Integrase core domain; Region: rve; pfam00665
553482005932	Integrase core domain; Region: rve_2; pfam13333
553482005933	HMMPfam hit to PF00665, Integrase core domain, score 5.4e-39
553482005934	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
553482005935	Transposase; Region: HTH_Tnp_1; cl17663
553482005936	HMMPfam hit to PF01527, Transposase, score 0.00051
553482005937	Muramidase (flagellum-specific) [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FlgJ; COG1705
553482005938	HMMPfam hit to PF01832, Mannosyl-glycoprotein endo-beta-N-ace, score 2.5e-36
553482005939	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482005940	transmembrane helices; other site
553482005941	Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Region: CitT; COG0471
553482005942	Anion permease ArsB/NhaD.  These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life.  A typical anion permease contains 8-13 transmembrane helices...; Region: ArsB_NhaD_permease; cl17221
553482005943	HMMPfam hit to PF00939, Sodium:sulfate symporter transmembrane, score 3e-06
553482005944	12 transmembrane helices predicted for SEQ1292 by TMHMM2.0 at aa 12-29, 39-61, 74-96, 125-147, 168-187, 207-229, 257-274, 279-298, 311-333, 353-375, 395-417 and 427-449
553482005945	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482005946	4 transmembrane helices predicted for SEQ1295 by TMHMM2.0 at aa 5-23, 38-60, 85-107 and 111-133
553482005947	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482005948	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
553482005949	non-specific DNA binding site [nucleotide binding]; other site
553482005950	salt bridge; other site
553482005951	sequence-specific DNA binding site [nucleotide binding]; other site
553482005952	HMMPfam hit to PF01381, Helix-turn-helix, score 2.2e-17
553482005953	Predicted helix-turn-helix motif with score 1884.000, SD 5.60 at aa 14-35, sequence ITQEELASILEVSRQTIGSLEN
553482005954	Transposase IS200 like; Region: Y1_Tnp; pfam01797
553482005955	HMMPfam hit to PF01797, Transposase IS200 like, score 1.3e-54
553482005956	Muramidase (flagellum-specific) [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FlgJ; COG1705
553482005957	HMMPfam hit to PF01832, Mannosyl-glycoprotein endo-beta-N-ace, score 8.7e-27
553482005958	1 transmembrane helix predicted for SEQ1298 by TMHMM2.0 at aa 21-40
553482005959	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
553482005960	active site
553482005961	phosphorylation site [posttranslational modification]
553482005962	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
553482005963	active site
553482005964	P-loop; other site
553482005965	phosphorylation site [posttranslational modification]
553482005966	Phosphotransferase system, fructose-specific IIC component [Carbohydrate transport and metabolism]; Region: FruA; COG1299
553482005967	10 transmembrane helices predicted for SEQ1299 by TMHMM2.0 at aa 295-317, 338-360, 370-392, 399-421, 441-462, 474-496, 524-546, 558-580, 595-617 and 624-643
553482005968	HMMPfam hit to PF02378, Phosphotransferase system, EIIC, score 3.6e-14
553482005969	PS00044 Bacterial regulatory proteins, lysR family signature.
553482005970	PS00583 pfkB family of carbohydrate kinases signature 1.
553482005971	HMMPfam hit to PF02379, PTS system, Fructose specific IIB subuni, score 1.7e-51
553482005972	HMMPfam hit to PF00359, Phosphoenolpyruvate-dependent sugar phos, score 8.9e-25
553482005973	Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB) [Carbohydrate transport and metabolism]; Region: FruK; COG1105
553482005974	1-phosphofructokinase (FruK), minor 6-phosphofructokinase (pfkB) and related sugar kinases. FruK plays an important role in the predominant pathway for fructose utilisation.This group also contains tagatose-6-phophate kinase, an enzyme of the tagatose...; Region: FruK_PfkB_like; cd01164
553482005975	putative substrate binding site [chemical binding]; other site
553482005976	putative ATP binding site [chemical binding]; other site
553482005977	HMMPfam hit to PF00294, pfkB family carbohydrate kinase, score 1.3e-56
553482005978	PS00584 pfkB family of carbohydrate kinases signature 2.
553482005979	PS00583 pfkB family of carbohydrate kinases signature 1.
553482005980	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
553482005981	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
553482005982	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
553482005983	HMMPfam hit to PF00455, Bacterial regulatory proteins, deoR family, score 1.1e-38
553482005984	HMMPfam hit to PF08220, DeoR-like helix-turn-helix domain, score 3.1e-10
553482005985	Predicted helix-turn-helix motif with score 985.000, SD 2.54 at aa 10-31, sequence VALEDLMQLLSSSESTVRRDLD
553482005986	2-dehydropantoate 2-reductase; Reviewed; Region: PRK06522
553482005987	Ketopantoate reductase PanE/ApbA; Region: ApbA; pfam02558
553482005988	Ketopantoate reductase PanE/ApbA C terminal; Region: ApbA_C; pfam08546
553482005989	HMMPfam hit to PF08546, Ketopantoate reductase PanE/ApbA C terminal, score 9.1e-55
553482005990	HMMPfam hit to PF02558, Ketopantoate reductase PanE/ApbA, score 5.3e-58
553482005991	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482005992	Predicted membrane protein, putative toxin regulator [General function prediction only]; Region: PfoR; COG3641
553482005993	Phosphotransferase system, EIIC; Region: PTS_EIIC_2; pfam13303
553482005994	8 transmembrane helices predicted for SEQ1303 by TMHMM2.0 at aa 16-38, 48-70, 109-131, 141-163, 184-206, 216-238, 266-288 and 308-330
553482005995	Thioredoxin reductase [Posttranslational modification, protein turnover, chaperones]; Region: TrxB; COG0492
553482005996	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
553482005997	HMMPfam hit to PF07992, Pyridine nucleotide-disulphide oxidoreduc, score 2.5e-13
553482005998	HMMPfam hit to PF00070, Pyridine nucleotide-disulphide oxidoreduc, score 2.7e-10
553482005999	1 transmembrane helix predicted for SEQ1304 by TMHMM2.0 at aa 5-24
553482006000	tRNA (guanine-N(1)-)-methyltransferase; Reviewed; Region: trmD; PRK00026
553482006001	HMMPfam hit to PF01746, tRNA (Guanine-1)-methyltransferase, score 7.9e-74
553482006002	16S rRNA-processing protein RimM; Provisional; Region: rimM; PRK00122
553482006003	RimM N-terminal domain; Region: RimM; pfam01782
553482006004	PRC-barrel domain; Region: PRC; pfam05239
553482006005	HMMPfam hit to PF05239, PRC-barrel domain, score 1.3e-17
553482006006	HMMPfam hit to PF01782, RimM N-terminal domain, score 7.4e-34
553482006007	gene remnant
553482006008	Predicted RNA-binding protein (contains KH domain) [General function prediction only]; Region: COG1837
553482006009	KH domain; Region: KH_4; pfam13083
553482006010	G-X-X-G motif; other site
553482006011	30S ribosomal protein S16; Reviewed; Region: rpsP; PRK00040
553482006012	HMMPfam hit to PF00886, Ribosomal protein S16, score 1.9e-30
553482006013	SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335
553482006014	5 transmembrane helices predicted for SEQ1309 by TMHMM2.0 at aa 15-34, 54-76, 86-108, 143-162 and 172-194
553482006015	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
553482006016	ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms]; Region: SalY; COG0577
553482006017	FtsX-like permease family; Region: FtsX; pfam02687
553482006018	HMMPfam hit to PF02687, Predicted permease, score 4.4e-45
553482006019	4 transmembrane helices predicted for SEQ1310 by TMHMM2.0 at aa 20-42, 284-306, 337-359 and 366-388
553482006020	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
553482006021	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
553482006022	Walker A/P-loop; other site
553482006023	ATP binding site [chemical binding]; other site
553482006024	Q-loop/lid; other site
553482006025	ABC transporter signature motif; other site
553482006026	Walker B; other site
553482006027	D-loop; other site
553482006028	H-loop/switch region; other site
553482006029	HMMPfam hit to PF00005, ABC transporter, score 1e-60
553482006030	PS00211 ABC transporters family signature.
553482006031	PS00017 ATP/GTP-binding site motif A (P-loop).
553482006032	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
553482006033	HlyD family secretion protein; Region: HlyD_3; pfam13437
553482006034	1 transmembrane helix predicted for SEQ1312 by TMHMM2.0 at aa 16-33
553482006035	carbamoyl phosphate synthase large subunit; Reviewed; Region: carB; PRK05294
553482006036	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
553482006037	Carbamoyl-phosphate synthase L chain, ATP binding domain; Region: CPSase_L_D2; pfam02786
553482006038	Carbamoyl-phosphate synthetase large chain, oligomerisation domain; Region: CPSase_L_D3; pfam02787
553482006039	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
553482006040	ATP-grasp domain; Region: ATP-grasp_4; cl17255
553482006041	Methylglyoxal synthase-like domain from type II glutamine-dependent carbamoyl phosphate synthetase (CSP). CSP, a CarA and CarB heterodimer, catalyzes the production of carbamoyl phosphate which is subsequently employed in the metabolic pathways...; Region: MGS_CPS_II; cd01424
553482006042	IMP binding site; other site
553482006043	dimer interface [polypeptide binding]; other site
553482006044	interdomain contacts; other site
553482006045	partial ornithine binding site; other site
553482006046	HMMPfam hit to PF02142, MGS-like domain, score 7.5e-26
553482006047	HMMPfam hit to PF02786, Carbamoyl-phosphate synthase L chain,, score 1.2e-32
553482006048	HMMPfam hit to PF02655, ATP-grasp domain, score 9.6e-06
553482006049	HMMPfam hit to PF02222, ATP-grasp domain, score 0.00013
553482006050	HMMPfam hit to PF01071, Phosphoribosylglycinamide synthetase,, score 0.00047
553482006051	PS00867 Carbamoyl-phosphate synthase subdomain signature 2.
553482006052	PS00866 Carbamoyl-phosphate synthase subdomain signature 1.
553482006053	HMMPfam hit to PF00289, Carbamoyl-phosphate synthase L chain,, score 1.9e-27
553482006054	HMMPfam hit to PF02787, Carbamoyl-phosphate synthetase large c, score 1e-60
553482006055	HMMPfam hit to PF02786, Carbamoyl-phosphate synthase L chain,, score 7.2e-139
553482006056	PS00867 Carbamoyl-phosphate synthase subdomain signature 2.
553482006057	PS00866 Carbamoyl-phosphate synthase subdomain signature 1.
553482006058	HMMPfam hit to PF00289, Carbamoyl-phosphate synthase L chain,, score 6.1e-56
553482006059	carbamoyl phosphate synthase small subunit; Reviewed; Region: PRK12564
553482006060	Carbamoyl-phosphate synthase small chain, CPSase domain; Region: CPSase_sm_chain; smart01097
553482006061	Small chain of the glutamine-dependent form of carbamoyl phosphate synthase, CPSase II; Region: GATase1_CPSase; cd01744
553482006062	catalytic site [active]
553482006063	subunit interface [polypeptide binding]; other site
553482006064	HMMPfam hit to PF00117, Glutamine amidotransferase class-I, score 2.7e-65
553482006065	PS00442 Glutamine amidotransferases class-I active site.
553482006066	HMMPfam hit to PF00988, Carbamoyl-phosphate synthase small ch, score 1.9e-87
553482006067	aspartate carbamoyltransferase catalytic subunit; Provisional; Region: pyrB; PRK00856
553482006068	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
553482006069	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
553482006070	HMMPfam hit to PF00185, Aspartate/ornithine carbamoyltransferase, As, score 3.2e-32
553482006071	Predicted helix-turn-helix motif with score 1181.000, SD 3.21 at aa 236-257, sequence FSKEDYHRQFGLTEERYRRLKD
553482006072	HMMPfam hit to PF02729, Aspartate/ornithine carbamoyltransferase, ca, score 1.4e-39
553482006073	PS00097 Aspartate and ornithine carbamoyltransferases signature.
553482006074	uracil transporter; Provisional; Region: PRK10720
553482006075	11 transmembrane helices predicted for SEQ1316 by TMHMM2.0 at aa 26-48, 55-77, 87-109, 120-142, 152-174, 176-198, 237-259, 310-332, 342-364, 376-394 and 399-416
553482006076	HMMPfam hit to PF00860, Permease family, score 2.9e-105
553482006077	PS01116 Xanthine/uracil permeases family signature.
553482006078	Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase [Nucleotide transport and metabolism]; Region: PyrR; COG2065
553482006079	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
553482006080	active site
553482006081	HMMPfam hit to PF00156, Phosphoribosyl transferase domain, score 2.1e-16
553482006082	Uncharacterized conserved protein [Function unknown]; Region: COG0398
553482006083	SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335
553482006084	5 transmembrane helices predicted for SEQ1318 by TMHMM2.0 at aa 13-32, 52-74, 81-103, 143-165 and 172-194
553482006085	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
553482006086	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
553482006087	RNA binding surface [nucleotide binding]; other site
553482006088	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
553482006089	active site
553482006090	HMMPfam hit to PF00849, RNA pseudouridylate synthase, score 5.9e-71
553482006091	PS01129 Rlu family of pseudouridine synthase signature.
553482006092	HMMPfam hit to PF01479, S4 domain, score 7.4e-09
553482006093	lipoprotein signal peptidase; Provisional; Region: PRK14797
553482006094	lipoprotein signal peptidase; Provisional; Region: PRK14787
553482006095	HMMPfam hit to PF01252, Signal peptidase (SPase) II, score 9.1e-44
553482006096	3 transmembrane helices predicted for SEQ1320 by TMHMM2.0 at aa 61-79, 84-103 and 123-145
553482006097	Transcriptional regulator [Transcription]; Region: LysR; COG0583
553482006098	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
553482006099	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
553482006100	dimerization interface [polypeptide binding]; other site
553482006101	HMMPfam hit to PF03466, LysR substrate binding domain, score 2.6e-12
553482006102	HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 9.8e-18
553482006103	PS00044 Bacterial regulatory proteins, lysR family signature.
553482006104	Predicted helix-turn-helix motif with score 1362.000, SD 3.83 at aa 16-37, sequence GTFREAASKLFVSQPSLSVSVK
553482006105	50S ribosomal protein L27; Validated; Region: rpmA; PRK05435
553482006106	HMMPfam hit to PF01016, Ribosomal L27 protein, score 1.2e-47
553482006107	PS00831 Ribosomal protein L27 signature.
553482006108	Protein of unknown function (DUF464); Region: DUF464; pfam04327
553482006109	HMMPfam hit to PF04327, Protein of unknown function (DUF464), score 2.5e-29
553482006110	50S ribosomal protein L21; Validated; Region: rplU; PRK05573
553482006111	HMMPfam hit to PF00829, Ribosomal prokaryotic L21 protein, score 5.1e-56
553482006112	PS01169 Ribosomal protein L21 signature.
553482006113	Bacterial capsule synthesis protein PGA_cap; Region: PGA_cap; smart00854
553482006114	CapA and related proteins, metallophosphatase domain; Region: MPP_CapA; cd07381
553482006115	putative active site [active]
553482006116	putative metal binding site [ion binding]; other site
553482006117	1 transmembrane helix predicted for SEQ1325 by TMHMM2.0 at aa 12-34
553482006118	Domain of Unknown Function with PDB structure (DUF3862); Region: DUF3862; pfam12978
553482006119	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482006120	H+ Antiporter protein; Region: 2A0121; TIGR00900
553482006121	11 transmembrane helices predicted for SEQ1327 by TMHMM2.0 at aa 13-35, 45-64, 76-95, 99-116, 137-159, 169-188, 229-251, 264-286, 306-335, 361-383 and 388-407
553482006122	CDS contains frameshifts after codons 286 and 326. Similar to Lactococcus lactis hypothetical protein UniProt:O87250 (EMBL:AE001272 (614 aa) fasta scores: E()=2e-32, 32.921% id in 647 aa
553482006123	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
553482006124	non-specific DNA binding site [nucleotide binding]; other site
553482006125	salt bridge; other site
553482006126	sequence-specific DNA binding site [nucleotide binding]; other site
553482006127	transcriptional activator, Rgg/GadR/MutR family, C-terminal domain; Region: RGG_Cterm; TIGR01716
553482006128	putative transposase OrfB; Reviewed; Region: PHA02517
553482006129	HTH-like domain; Region: HTH_21; pfam13276
553482006130	Integrase core domain; Region: rve; pfam00665
553482006131	Integrase core domain; Region: rve_2; pfam13333
553482006132	HMMPfam hit to PF00665, Integrase core domain, score 5.4e-39
553482006133	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
553482006134	Transposase; Region: HTH_Tnp_1; cl17663
553482006135	HMMPfam hit to PF01527, Transposase, score 0.00051
553482006136	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3464
553482006137	Transposase; Region: DDE_Tnp_ISL3; pfam01610
553482006138	Predicted helix-turn-helix motif with score 1838.000, SD 5.45 at aa 119-140, sequence VSMTAIADRLSISTSTVMRKLN
553482006139	HMMPfam hit to PF01610, Transposase, score 2.7e-19
553482006140	30S ribosomal protein S1; Reviewed; Region: rpsA; PRK06676
553482006141	S1_RPS1_repeat_ec1_hs1: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture...; Region: S1_RPS1_repeat_ec1_hs1; cd05687
553482006142	RNA binding site [nucleotide binding]; other site
553482006143	S1_RPS1_repeat_ec2_hs2: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture...; Region: S1_RPS1_repeat_ec2_hs2; cd04465
553482006144	RNA binding site [nucleotide binding]; other site
553482006145	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
553482006146	RNA binding site [nucleotide binding]; other site
553482006147	S1_RPS1_repeat_hs4: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_hs4; cd05692
553482006148	RNA binding site [nucleotide binding]; other site
553482006149	HMMPfam hit to PF00575, S1 RNA binding domain, score 3e-30
553482006150	HMMPfam hit to PF00575, S1 RNA binding domain, score 2.5e-27
553482006151	HMMPfam hit to PF00575, S1 RNA binding domain, score 3.5e-15
553482006152	HMMPfam hit to PF00575, S1 RNA binding domain, score 0.004
553482006153	Protein of unknown function (DUF2969); Region: DUF2969; pfam11184
553482006154	branched-chain amino acid aminotransferase; Provisional; Region: PRK13357
553482006155	BCAT_beta_family: Branched-chain aminotransferase catalyses the transamination of the branched-chain amino acids  leusine, isoleucine and valine to their respective alpha-keto acids, alpha-ketoisocaproate, alpha-keto-beta-methylvalerate and...; Region: BCAT_beta_family; cd01557
553482006156	homodimer interface [polypeptide binding]; other site
553482006157	substrate-cofactor binding pocket; other site
553482006158	catalytic residue [active]
553482006159	HMMPfam hit to PF01063, Aminotransferase class IV, score 9.8e-115
553482006160	PS00770 Aminotransferases class-IV signature.
553482006161	DNA topoisomerase IV, A subunit, Gram-positive; Region: parC_Gpos; TIGR01061
553482006162	DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes...; Region: TOP4c; cd00187
553482006163	CAP-like domain; other site
553482006164	active site
553482006165	primary dimer interface [polypeptide binding]; other site
553482006166	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
553482006167	HMMPfam hit to PF03989, DNA gyrase C-terminal domain, beta-prop, score 0.045
553482006168	HMMPfam hit to PF03989, DNA gyrase C-terminal domain, beta-prop, score 9.6e-11
553482006169	HMMPfam hit to PF03989, DNA gyrase C-terminal domain, beta-prop, score 0.1
553482006170	HMMPfam hit to PF03989, DNA gyrase C-terminal domain, beta-prop, score 9.2e-05
553482006171	HMMPfam hit to PF03989, DNA gyrase C-terminal domain, beta-prop, score 0.062
553482006172	HMMPfam hit to PF00521, DNA gyrase/topoisomerase IV, subunit A, score 7.6e-278
553482006173	DNA topoisomerase IV, B subunit, Gram-positive; Region: parE_Gpos; TIGR01058
553482006174	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
553482006175	Mg2+ binding site [ion binding]; other site
553482006176	G-X-G motif; other site
553482006177	TopoIIA_Trans_DNA_gyrase: Transducer domain, having a ribosomal S5 domain 2-like fold, of the type found in proteins of the type IIA family of DNA topoisomerases similar to the B subunits of E. coli DNA gyrase and E. coli Topoisomerase IV which are; Region: TopoII_Trans_DNA_gyrase; cd00822
553482006178	anchoring element; other site
553482006179	dimer interface [polypeptide binding]; other site
553482006180	ATP binding site [chemical binding]; other site
553482006181	TOPRIM_TopoIIA_GyrB: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in proteins of the type IIA family of DNA topoisomerases similar to the Escherichia coli GyrB subunit. TopoIIA enzymes cut both strands of the...; Region: TOPRIM_TopoIIA_GyrB; cd03366
553482006182	active site
553482006183	putative metal-binding site [ion binding]; other site
553482006184	DNA gyrase B subunit, carboxyl terminus; Region: DNA_gyraseB_C; pfam00986
553482006185	HMMPfam hit to PF00986, DNA gyrase B subunit, carboxyl terminus, score 4.5e-44
553482006186	HMMPfam hit to PF01751, Toprim domain, score 0.00085
553482006187	PS00177 DNA topoisomerase II signature.
553482006188	HMMPfam hit to PF00204, DNA gyrase B, score 1.6e-86
553482006189	HMMPfam hit to PF02518, Histidine kinase-, DNA gyrase B-, and H, score 1e-29
553482006190	putative glycerol-3-phosphate acyltransferase PlsY; Provisional; Region: PRK00220
553482006191	6 transmembrane helices predicted for SEQ1341 by TMHMM2.0 at aa 5-27, 42-61, 68-90, 105-127, 134-156 and 166-183
553482006192	HMMPfam hit to PF02660, Domain of unknown function DUF, score 3.7e-52
553482006193	dihydroorotase; Validated; Region: pyrC; PRK09357
553482006194	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
553482006195	Dihydroorotase (DHOase), subgroup IIa; DHOases catalyze the reversible interconversion of carbamoyl aspartate to dihydroorotate, a key reaction in pyrimidine biosynthesis. This subgroup also contains proteins that lack the active site, like unc-33, a C; Region: DHOase_IIa; cd01317
553482006196	active site
553482006197	HMMPfam hit to PF01979, Amidohydrolase family, score 9.1e-19
553482006198	HMMPfam hit to PF07969, Amidohydrolase family, score 0.00052
553482006199	PS00483 Dihydroorotase signature 2.
553482006200	PS00482 Dihydroorotase signature 1.
553482006201	Family 1 of Uracil-DNA glycosylase (UDG) enzymes; Region: UDG_F1; cd10027
553482006202	ligand binding site [chemical binding]; other site
553482006203	active site
553482006204	UGI interface [polypeptide binding]; other site
553482006205	catalytic site [active]
553482006206	PS00130 Uracil-DNA glycosylase signature.
553482006207	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
553482006208	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
553482006209	Coenzyme A binding pocket [chemical binding]; other site
553482006210	HMMPfam hit to PF00583, Acetyltransferase (GNAT) family, score 2.3e-16
553482006211	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
553482006212	dimer interface [polypeptide binding]; other site
553482006213	conserved gate region; other site
553482006214	putative PBP binding loops; other site
553482006215	ABC-ATPase subunit interface; other site
553482006216	HMMPfam hit to PF00528, Binding-protein-dependent transport syst, score 2.5e-29
553482006217	5 transmembrane helices predicted for SEQ1345 by TMHMM2.0 at aa 20-42, 54-76, 80-102, 123-145 and 184-202
553482006218	PS00402 Binding-protein-dependent transport systems inner membrane comp. sign.
553482006219	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
553482006220	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
553482006221	substrate binding pocket [chemical binding]; other site
553482006222	membrane-bound complex binding site; other site
553482006223	hinge residues; other site
553482006224	HMMPfam hit to PF00497, Bacterial extracellular solute-binding prot, score 2.6e-69
553482006225	PS01039 Bacterial extracellular solute-binding proteins, family 3 signature.
553482006226	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482006227	amidase; Provisional; Region: PRK06529
553482006228	Amidase; Region: Amidase; cl11426
553482006229	HMMPfam hit to PF01425, Amidase, score 9.9e-74
553482006230	PS00571 Amidases signature.
553482006231	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
553482006232	Coenzyme A binding pocket [chemical binding]; other site
553482006233	HMMPfam hit to PF00583, Acetyltransferase (GNAT) family, score 7.8e-12
553482006234	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
553482006235	active site
553482006236	HMMPfam hit to PF00156, Phosphoribosyl transferase domain, score 1.8e-28
553482006237	PS00103 Purine/pyrimidine phosphoribosyl transferases signature.
553482006238	PS00626 Regulator of chromosome condensation (RCC1) signature 2.
553482006239	Orotidine 5'-phosphate decarboxylase (ODCase) is a dimeric enzyme that decarboxylates orotidine 5'-monophosphate (OMP) to form uridine 5'-phosphate (UMP), an essential step in the pyrimidine biosynthetic pathway. In mammals, UMP synthase...; Region: OMP_decarboxylase_like; cd04725
553482006240	active site
553482006241	dimer interface [polypeptide binding]; other site
553482006242	HMMPfam hit to PF00215, Orotidine 5'-phosphate decarboxylase / HUMP, score 5.5e-76
553482006243	PS00156 Orotidine 5'-phosphate decarboxylase active site.
553482006244	Transcriptional regulator [Transcription]; Region: LysR; COG0583
553482006245	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
553482006246	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
553482006247	dimerization interface [polypeptide binding]; other site
553482006248	HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix protei, score 3.7e-19
553482006249	Predicted helix-turn-helix motif with score 1543.000, SD 4.44 at aa 16-37, sequence GSMNEAAKQLFITQPSLSNAVK
553482006250	PS00044 Bacterial regulatory proteins, lysR family signature.
553482006251	CRISPR/Cas system-associated protein Csm6; Region: Csm6_III-A; cl09873
553482006252	purine nucleoside phosphorylase; Provisional; Region: PRK08202
553482006253	HMMPfam hit to PF00896, Phosphorylase family, score 1.2e-102
553482006254	PS01240 Purine and other phosphorylases family 2 signature.
553482006255	phosphopentomutase; Provisional; Region: PRK05362
553482006256	Metalloenzyme superfamily; Region: Metalloenzyme; pfam01676
553482006257	HMMPfam hit to PF08342, Phosphopentomutase N-terminal, score 9.1e-47
553482006258	RPI_A: Ribose 5-phosphate isomerase type A (RPI_A) subfamily; RPI catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate, the first step of the non-oxidative branch of the pentose phosphate pathway. This reaction leads to the...; Region: RPI_A; cd01398
553482006259	tetramer (dimer of dimers) interface [polypeptide binding]; other site
553482006260	active site
553482006261	dimer interface [polypeptide binding]; other site
553482006262	HMMPfam hit to PF06026, Ribose 5-phosphate isomerase A (phosph, score 2.6e-95
553482006263	Domain of unknown function (DUF4176); Region: DUF4176; pfam13780
553482006264	4 transmembrane helices predicted for SEQ1358 by TMHMM2.0 at aa 52-74, 89-111, 151-173 and 188-210
553482006265	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482006266	4 transmembrane helices predicted for SEQ1359 by TMHMM2.0 at aa 53-75, 90-112, 154-176 and 191-213
553482006267	4 transmembrane helices predicted for SEQ1360 by TMHMM2.0 at aa 53-75, 90-112, 150-172 and 185-207
553482006268	type VII secretion effector, SACOL2603 family; Region: T7SS_SACOL2603; TIGR04197
553482006269	gene remnant. Similar to the C-terminal region of Streptococcus agalactiae serotype Ia uncharacterized protein UniProt:Q3K164 (EMBL:CP000114) (104 aa) fasta scores: E()=4.8e-14, 50.0% id in 74 aa
553482006270	tRNA modification GTPase TrmE; Reviewed; Region: trmE; PRK05291
553482006271	GTP-binding protein TrmE N-terminus; Region: TrmE_N; pfam10396
553482006272	trmE is a tRNA modification GTPase; Region: trmE; cd04164
553482006273	G1 box; other site
553482006274	GTP/Mg2+ binding site [chemical binding]; other site
553482006275	Switch I region; other site
553482006276	G2 box; other site
553482006277	Switch II region; other site
553482006278	G3 box; other site
553482006279	G4 box; other site
553482006280	G5 box; other site
553482006281	Catalytic cysteine-containing C-terminus of GTPase, MnmE; Region: GTPase_Cys_C; pfam12631
553482006282	HMMPfam hit to PF01926, GTPase of unknown function, score 1.3e-45
553482006283	PS00017 ATP/GTP-binding site motif A (P-loop).
553482006284	dipeptidase PepV; Reviewed; Region: PRK07318
553482006285	M20 Peptidase Xaa-His dipeptidase (PepV) degrades hydrophobic dipeptides; Region: M20_PepV; cd03888
553482006286	active site
553482006287	metal binding site [ion binding]; metal-binding site
553482006288	HMMPfam hit to PF01546, Peptidase family M20/M25/M40, score 8.9e-32
553482006289	PS00759 ArgE / dapE / ACY1 / CPG2 / yscS family signature 2.
553482006290	PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1.
553482006291	Nitroreductase-like family 1. A subfamily of the nitroreductase family containing uncharacterized proteins that are similar to nitroreductase. Nitroreductase catalyzes the reduction of nitroaromatic compounds such as nitrotoluenes, nitrofurans and...; Region: Nitroreductase_1; cd02137
553482006292	dimer interface [polypeptide binding]; other site
553482006293	FMN binding site [chemical binding]; other site
553482006294	HMMPfam hit to PF00881, Nitroreductase family, score 6.8e-18
553482006295	excinuclease ABC subunit C; Validated; Region: uvrC; PRK00558
553482006296	Catalytic GIY-YIG domain of nucleotide excision repair endonucleases UvrC, Cho, and similar proteins; Region: GIY-YIG_UvrC_Cho; cd10434
553482006297	GIY-YIG motif/motif A; other site
553482006298	active site
553482006299	catalytic site [active]
553482006300	putative DNA binding site [nucleotide binding]; other site
553482006301	metal binding site [ion binding]; metal-binding site
553482006302	UvrB/uvrC motif; Region: UVR; pfam02151
553482006303	UvrC Helix-hairpin-helix N-terminal; Region: UvrC_HhH_N; pfam08459
553482006304	HMMPfam hit to PF08459, UvrC Helix-hairpin-helix N-terminal, score 5.7e-88
553482006305	HMMPfam hit to PF02151, UvrB/uvrC motif, score 8.6e-09
553482006306	HMMPfam hit to PF01541, GIY-YIG catalytic domain, score 2.6e-33
553482006307	ABC-type Fe3+ transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: AfuA; COG1840
553482006308	Bacterial extracellular solute-binding protein; Region: SBP_bac_8; pfam13416
553482006309	HMMPfam hit to PF01547, Bacterial extracellular solute-binding prot, score 5.4e-07
553482006310	1 transmembrane helix predicted for SEQ1369 by TMHMM2.0 at aa 7-26
553482006311	Response regulator receiver domain; Region: Response_reg; pfam00072
553482006312	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
553482006313	active site
553482006314	phosphorylation site [posttranslational modification]
553482006315	intermolecular recognition site; other site
553482006316	dimerization interface [polypeptide binding]; other site
553482006317	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
553482006318	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
553482006319	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
553482006320	HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix pr, score 6.6e-06
553482006321	HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix pr, score 6.7e-10
553482006322	Predicted helix-turn-helix motif with score 1260.000, SD 3.48 at aa 165-186, sequence IMIGQLAHDLGYSESHLYHLAK
553482006323	HMMPfam hit to PF00072, Response regulator receiver domain, score 1.2e-16
553482006324	Predicted signal transduction protein with a C-terminal ATPase domain [Signal transduction mechanisms]; Region: COG2972
553482006325	Histidine kinase; Region: His_kinase; pfam06580
553482006326	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
553482006327	Mg2+ binding site [ion binding]; other site
553482006328	G-X-G motif; other site
553482006329	HMMPfam hit to PF06580, Histidine kinase, score 4.7e-30
553482006330	2 transmembrane helices predicted for SEQ1371 by TMHMM2.0 at aa 21-43 and 254-276
553482006331	Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IID [Carbohydrate transport and metabolism]; Region: ManZ; COG3716
553482006332	HMMPfam hit to PF03613, PTS system mannose/fructose/sorbose family I, score 1.9e-134
553482006333	5 transmembrane helices predicted for SEQ1372 by TMHMM2.0 at aa 35-52, 126-148, 155-174, 232-249 and 256-274
553482006334	Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIC [Carbohydrate transport and metabolism]; Region: ManY; COG3715
553482006335	HMMPfam hit to PF03609, PTS system sorbose-specific iic component, score 8.7e-38
553482006336	7 transmembrane helices predicted for SEQ1373 by TMHMM2.0 at aa 4-23, 30-52, 62-84, 96-118, 143-165, 178-200 and 210-232
553482006337	PTS system sorbose subfamily IIB component; Region: PTSIIB_sorb; pfam03830
553482006338	active site
553482006339	phosphorylation site [posttranslational modification]
553482006340	HMMPfam hit to PF03830, PTS system sorbose subfamily IIB componen, score 6.8e-71
553482006341	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cl00025
553482006342	active pocket/dimerization site; other site
553482006343	active site
553482006344	phosphorylation site [posttranslational modification]
553482006345	HMMPfam hit to PF03610, PTS system fructose IIA component, score 0.00028
553482006346	Predicted membrane protein [Function unknown]; Region: COG2855
553482006347	8 transmembrane helices predicted for SEQ1376 by TMHMM2.0 at aa 22-44, 57-79, 84-106, 118-140, 150-172, 257-279, 289-308 and 315-337
553482006348	HMMPfam hit to PF03601, Conserved hypothetical protein, score 1.4e-129
553482006349	methionine sulfoxide reductase B; Provisional; Region: PRK00222
553482006350	SelR domain; Region: SelR; pfam01641
553482006351	HMMPfam hit to PF01641, SelR domain, score 3.1e-79
553482006352	GTP-binding protein LepA; Provisional; Region: PRK05433
553482006353	LepA also known as Elongation Factor 4 (EF4); Region: LepA; cd01890
553482006354	G1 box; other site
553482006355	putative GEF interaction site [polypeptide binding]; other site
553482006356	GTP/Mg2+ binding site [chemical binding]; other site
553482006357	Switch I region; other site
553482006358	G2 box; other site
553482006359	G3 box; other site
553482006360	Switch II region; other site
553482006361	G4 box; other site
553482006362	G5 box; other site
553482006363	lepA_II: This subfamily represents the domain II of LepA, a GTP-binding protein localized in the cytoplasmic membrane. The N-terminal domain of LepA shares regions of homology to translation factors. In terms of interaction with the ribosome, EF-G, EF-Tu...; Region: lepA_II; cd03699
553482006364	lepA_C: This family represents the C-terminal region of LepA, a GTP-binding protein localized in the cytoplasmic membrane.   LepA is ubiquitous in Bacteria and Eukaryota (e.g. Saccharomyces cerevisiae GUF1p), but is missing from Archaea. LepA exhibits...; Region: lepA_C; cd03709
553482006365	GTP-binding protein LepA C-terminus; Region: LepA_C; pfam06421
553482006366	HMMPfam hit to PF06421, GTP-binding protein LepA C-terminus, score 2.5e-82
553482006367	HMMPfam hit to PF00679, Elongation factor G C-terminus, score 3.6e-41
553482006368	HMMPfam hit to PF03144, Elongation factor Tu domain, score 9.4e-06
553482006369	HMMPfam hit to PF00009, Elongation factor Tu GTP binding domain, score 1.1e-71
553482006370	PS00301 GTP-binding elongation factors signature.
553482006371	PS00017 ATP/GTP-binding site motif A (P-loop).
553482006372	gene remnant. Similar to the C-terminal region of Streptococcus agalactiae hypothetical protein UniProt:Q3D902 (EMBL:AAJR01000020 (133 aa) fasta scores: E()=2.4e-14, 56.522% id in 92 aa
553482006373	2 transmembrane helices predicted for SEQ1380 by TMHMM2.0 at aa 27-46 and 59-81
553482006374	Enterocin A Immunity; Region: EntA_Immun; pfam08951
553482006375	Class II bacteriocin; Region: Bacteriocin_II; pfam01721
553482006376	gene remnant. Similar to the C-terminal region of Streptococcus pyogenes serotype M3 bacteriocin processing peptidase/bacteriocin export ABC transporter UniProt:Q1J803 (EMBL:CP000262 (717 aa) fasta scores: E()=3e-32, 81.935% id in 155 aa
553482006377	HMMPfam hit to PF00005, ABC transporter, score 7.3e-19
553482006378	PS00211 ABC transporters family signature.
553482006379	Transposase [DNA replication, recombination, and repair]; Region: COG5421
553482006380	Transposase [DNA replication, recombination, and repair]; Region: COG5421
553482006381	CDS contains nonsense mutations (ochre and amber) after codons 204 and 284. Similar to Streptococcus pneumoniae transport protein ComB UniProt:P36498 (EMBL:AE005672 (449 aa) fasta scores: E()=3.8e-43, 34.824% id in 425 aa
553482006382	COMC family; Region: ComC; pfam03047
553482006383	HMMPfam hit to PF08128, Double glycine cleavage site bacterio, score 2.6e-11
553482006385	HMMPfam hit to PF01797, Transposase IS200 like, score 4.8e-23
553482006386	Transposase IS200 like; Region: Y1_Tnp; pfam01797
553482006387	HMMPfam hit to PF01797, Transposase IS200 like, score 9.7e-54
553482006388	Ribosomal protein L7/L12. Ribosomal protein L7/L12 refers to the large ribosomal subunit proteins L7 and L12, which are identical except that L7 is acetylated at the N terminus. It is a component of the L7/L12 stalk, which is located at the surface of...; Region: Ribosomal_L7_L12; cd00387
553482006389	core dimer interface [polypeptide binding]; other site
553482006390	L10 interface [polypeptide binding]; other site
553482006391	L11 interface [polypeptide binding]; other site
553482006392	putative EF-Tu interaction site [polypeptide binding]; other site
553482006393	putative EF-G interaction site [polypeptide binding]; other site
553482006394	HMMPfam hit to PF00542, Ribosomal protein L7/L12 C-terminal dom, score 4.3e-37
553482006395	Ribosomal protein L10 family, L10 subfamily; composed of bacterial 50S ribosomal protein and eukaryotic mitochondrial 39S ribosomal protein, L10. L10 occupies the L7/L12 stalk of the ribosome. The N-terminal domain (NTD) of L10 interacts with L11 protein...; Region: Ribosomal_L10; cd05797
553482006396	23S rRNA interface [nucleotide binding]; other site
553482006397	Interface with L7/L12 ribosomal proteins [polypeptide binding]; other site
553482006398	HMMPfam hit to PF00466, Ribosomal protein L10, score 2.2e-28
553482006399	Protein of unknown function (DUF1461); Region: DUF1461; cl01862
553482006400	4 transmembrane helices predicted for SEQ1392 by TMHMM2.0 at aa 7-29, 91-113, 120-142 and 178-200
553482006401	HMMPfam hit to PF07314, Protein of unknown function (DUF1461), score 1.2e-81
553482006402	PS00225 Crystallins beta and gamma 'Greek key' motif signature.
553482006403	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482006404	HAD-superfamily subfamily IIA hydrolase, TIGR01457; Region: HAD-SF-IIA-hyp2
553482006405	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
553482006406	active site
553482006407	motif I; other site
553482006408	motif II; other site
553482006409	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
553482006410	HMMPfam hit to PF00702, haloacid dehalogenase-like hydrolase, score 1.8e-22
553482006411	Acyl-ACP thioesterase; Region: Acyl-ACP_TE; pfam01643
553482006412	4-hydroxybenzoyl-CoA thioesterase (4HBT). Catalyzes the final step in the 4-chlorobenzoate degradation pathway in which 4-chlorobenzoate is converted to 4-hydroxybenzoate in certain soil-dwelling bacteria. 4HBT forms a homotetramer with four active sites; Region: 4HBT; cd00586
553482006413	active site
553482006414	The hotdog fold was initially identified in the E. coli FabA (beta-hydroxydecanoyl-acyl carrier protein (ACP)-dehydratase) structure and subsequently in 4HBT (4-hydroxybenzoyl-CoA thioesterase) from Pseudomonas. A number of other seemingly unrelated...; Region: hot_dog; cl00509
553482006415	active site 2 [active]
553482006416	active site 1 [active]
553482006417	HMMPfam hit to PF01643, Acyl-ACP thioesterase, score 4.1e-95
553482006418	coproporphyrinogen III oxidase; Provisional; Region: PRK08599
553482006419	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
553482006420	FeS/SAM binding site; other site
553482006421	HemN C-terminal domain; Region: HemN_C; pfam06969
553482006422	HMMPfam hit to PF06969, HemN C-terminal region, score 4.7e-45
553482006423	Acetyltransferase (GNAT) domain; Region: Acetyltransf_8; pfam13523
553482006424	phosphoglucosamine mutase; Provisional; Region: glmM; PRK14316
553482006425	GlmM is a bacterial phosphoglucosamine mutase (PNGM) that belongs to the alpha-D-phosphohexomutase superfamily. It is required for the interconversion of glucosamine-6-phosphate and glucosamine-1-phosphate in the biosynthetic pathway of...; Region: GlmM; cd05802
553482006426	active site
553482006427	substrate binding site [chemical binding]; other site
553482006428	metal binding site [ion binding]; metal-binding site
553482006429	HMMPfam hit to PF00408, Phosphoglucomutase/phosphomannomutase, C-, score 4e-06
553482006430	HMMPfam hit to PF02880, Phosphoglucomutase/phosphomannomutase, al, score 4.8e-24
553482006431	HMMPfam hit to PF02879, Phosphoglucomutase/phosphomannomutase, al, score 2.5e-20
553482006432	HMMPfam hit to PF02878, Phosphoglucomutase/phosphomannomutase, al, score 2.5e-58
553482006433	PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature.
553482006434	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4856
553482006435	YbbR-like protein; Region: YbbR; pfam07949
553482006436	YbbR-like protein; Region: YbbR; pfam07949
553482006437	HMMPfam hit to PF07949, YbbR-like protein, score 0.00012
553482006438	HMMPfam hit to PF07949, YbbR-like protein, score 9.8e-13
553482006439	HMMPfam hit to PF07949, YbbR-like protein, score 1.9e-13
553482006440	1 transmembrane helix predicted for SEQ1398 by TMHMM2.0 at aa 7-29
553482006441	Uncharacterized conserved protein [Function unknown]; Region: COG1624
553482006442	DisA bacterial checkpoint controller nucleotide-binding; Region: DisA_N; pfam02457
553482006443	HMMPfam hit to PF02457, Domain of unknown function DUF147, score 8.4e-59
553482006444	3 transmembrane helices predicted for SEQ1399 by TMHMM2.0 at aa 15-37, 49-71 and 81-100
553482006445	UDP-N-acetylmuramyl tripeptide synthase [Cell envelope biogenesis, outer membrane]; Region: MurE; COG0769
553482006446	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
553482006447	Domain of unknown function (DUF1727); Region: DUF1727; pfam08353
553482006448	HMMPfam hit to PF08245, Mur ligase middle domain, score 1.1e-06
553482006449	HMMPfam hit to PF08353, Domain of unknown function (DUF1727), score 7e-55
553482006450	Type 1 glutamine amidotransferase (GATase1) domain found in Cobyric Acid Synthase (CobQ); Region: GATase1_CobQ; cd01750
553482006451	catalytic triad [active]
553482006452	HMMPfam hit to PF07685, CobB/CobQ-like glutamine amidotransferase do, score 4.3e-49
553482006453	Lipoate-protein ligase A [Coenzyme metabolism]; Region: LplA; COG0095
553482006454	lipoyltransferase and lipoate-protein ligase; Region: lipoyltrans; TIGR00545
553482006455	Bacterial lipoate protein ligase C-terminus; Region: Lip_prot_lig_C; pfam10437
553482006456	HMMPfam hit to PF03099, Biotin/lipoate A/B protein ligase famil, score 1.7e-22
553482006457	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
553482006458	E3 interaction surface; other site
553482006459	lipoyl attachment site [posttranslational modification]; other site
553482006460	dihydrolipoamide dehydrogenase; Region: lipoamide_DH; TIGR01350
553482006461	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
553482006462	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
553482006463	HMMPfam hit to PF02852, Pyridine nucleotide-disulphide oxidored, score 1e-52
553482006464	HMMPfam hit to PF01134, Glucose inhibited division protein A, score 1.2e-05
553482006465	HMMPfam hit to PF07992, Pyridine nucleotide-disulphide oxidored, score 1.4e-60
553482006466	HMMPfam hit to PF00070, Pyridine nucleotide-disulphide oxidored, score 1.2e-27
553482006467	PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site.
553482006468	HMMPfam hit to PF00364, Biotin-requiring enzyme, score 1.5e-22
553482006469	PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site.
553482006470	branched-chain alpha-keto acid dehydrogenase subunit E2; Reviewed; Region: PRK11856
553482006471	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
553482006472	E3 interaction surface; other site
553482006473	lipoyl attachment site [posttranslational modification]; other site
553482006474	e3 binding domain; Region: E3_binding; pfam02817
553482006475	e3 binding domain; Region: E3_binding; pfam02817
553482006476	2-oxoacid dehydrogenases acyltransferase (catalytic domain); Region: 2-oxoacid_dh; pfam00198
553482006477	HMMPfam hit to PF00198, 2-oxoacid dehydrogenases acyltransferas, score 8.6e-116
553482006478	HMMPfam hit to PF02817, e3 binding domain, score 3.4e-15
553482006479	HMMPfam hit to PF02817, e3 binding domain, score 1.2e-16
553482006480	HMMPfam hit to PF00364, Biotin-requiring enzyme, score 3e-22
553482006481	PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site.
553482006482	Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit [Energy production and conversion]; Region: AcoB; COG0022
553482006483	Pyrimidine (PYR) binding domain of the beta subunits of the E1 components of human pyruvate dehydrogenase complex (E1- PDHc) and related proteins; Region: TPP_PYR_E1-PDHc-beta_like; cd07036
553482006484	alpha subunit interface [polypeptide binding]; other site
553482006485	TPP binding site [chemical binding]; other site
553482006486	heterodimer interface [polypeptide binding]; other site
553482006487	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
553482006488	HMMPfam hit to PF02780, Transketolase, C-terminal domain, score 5.9e-55
553482006489	HMMPfam hit to PF02779, Transketolase, pyridine binding domai, score 1.1e-64
553482006490	Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit [Energy production and conversion]; Region: AcoA; COG1071
553482006491	Thiamine pyrophosphate (TPP) family, E1 of PDC_ADC_BCADC subfamily, TPP-binding module; composed of proteins similar to the E1 components of the human pyruvate dehydrogenase complex (PDC), the acetoin dehydrogenase complex (ADC) and the branched chain...; Region: TPP_E1_PDC_ADC_BCADC; cd02000
553482006492	tetramer interface [polypeptide binding]; other site
553482006493	TPP-binding site [chemical binding]; other site
553482006494	heterodimer interface [polypeptide binding]; other site
553482006495	phosphorylation loop region [posttranslational modification]
553482006496	HMMPfam hit to PF00676, Dehydrogenase E1 component, score 6.6e-106
553482006497	ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only]; Region: Uup; COG0488
553482006498	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
553482006499	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
553482006500	ABC transporter; Region: ABC_tran_2; pfam12848
553482006501	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
553482006502	HMMPfam hit to PF00005, ABC transporter, score 2.5e-32
553482006503	PS00017 ATP/GTP-binding site motif A (P-loop).
553482006504	HMMPfam hit to PF00005, ABC transporter, score 5.2e-46
553482006505	PS00017 ATP/GTP-binding site motif A (P-loop).
553482006506	Predicted esterase [General function prediction only]; Region: COG0627
553482006507	S-formylglutathione hydrolase; Region: PLN02442
553482006508	Predicted hydrolase of the alpha/beta superfamily [General function prediction only]; Region: COG2819
553482006509	HMMPfam hit to PF02230, Phospholipase/Carboxylesterase, score 0.0017
553482006510	HMMPfam hit to PF00756, esterase, score 1.3e-05
553482006511	mRNA degradation ribonucleases J1/J2 (metallo-beta-lactamase superfamily) [Translation, ribosomal structure and biogenesis; Replication, recombination and repair]; Region: COG0595
553482006512	Metallo-beta-lactamase superfamily; Region: Lactamase_B; pfam00753
553482006513	RNA-metabolising metallo-beta-lactamase; Region: RMMBL; pfam07521
553482006514	HMMPfam hit to PF07521, RNA-metabolising metallo-beta-lactamase, score 3e-11
553482006515	ABC-type uncharacterized transport system, ATPase component [General function prediction only]; Region: PhnK; COG1101
553482006516	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
553482006517	Walker A/P-loop; other site
553482006518	ATP binding site [chemical binding]; other site
553482006519	Q-loop/lid; other site
553482006520	ABC transporter signature motif; other site
553482006521	Walker B; other site
553482006522	D-loop; other site
553482006523	H-loop/switch region; other site
553482006524	HMMPfam hit to PF00005, ABC transporter, score 2e-43
553482006525	PS00211 ABC transporters family signature.
553482006526	PS00017 ATP/GTP-binding site motif A (P-loop).
553482006527	Transmembrane subunit (TM) of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which are involved in the uptake of branched-chain amino acids (AAs), as well as TMs of transporters involved in the uptake of...; Region: TM_PBP1_branched-chain-AA_like; cd06574
553482006528	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
553482006529	TM-ABC transporter signature motif; other site
553482006530	8 transmembrane helices predicted for SEQ1411 by TMHMM2.0 at aa 9-28, 54-76, 83-105, 125-147, 176-195, 205-227, 234-256 and 260-282
553482006531	HMMPfam hit to PF02653, Branched-chain amino acid transport syst, score 8.2e-23
553482006532	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482006533	Type I periplasmic ligand-binding domain of uncharacterized ABC-type transport systems that are predicted to be involved in the uptake of amino acids, peptides, or inorganic ions; Region: PBP1_ABC_uncharacterized_transporter; cd06325
553482006534	zinc binding site [ion binding]; other site
553482006535	putative ligand binding site [chemical binding]; other site
553482006536	HMMPfam hit to PF04392, ABC transporter substrate binding protei, score 5e-129
553482006537	1 transmembrane helix predicted for SEQ1412 by TMHMM2.0 at aa 5-23
553482006538	Predicted RNA-binding protein homologous to eukaryotic snRNP [Transcription]; Region: COG1293
553482006539	Domain of unknown function (DUF814); Region: DUF814; pfam05670
553482006540	HMMPfam hit to PF05833, Fibronectin-binding protein A N-terminus (Fb, score 3.2e-228
553482006541	HMMPfam hit to PF05670, Domain of unknown function (DUF814), score 8.7e-39
553482006542	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
553482006543	TPR motif; other site
553482006544	binding surface
553482006545	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
553482006546	binding surface
553482006547	TPR motif; other site
553482006548	HMMPfam hit to PF07719, Tetratricopeptide repeat, score 2e-05
553482006549	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; COG0628
553482006550	Domain of unknown function DUF20; Region: UPF0118; pfam01594
553482006551	HMMPfam hit to PF01594, Domain of unknown function DUF20, score 3.9e-71
553482006552	7 transmembrane helices predicted for SEQ1415 by TMHMM2.0 at aa 18-40, 49-71, 86-108, 178-200, 240-262, 269-291 and 332-354
553482006553	MutT homolog-1 (MTH1) is a member of the Nudix hydrolase superfamily. MTH1, the mammalian counterpart of MutT, hydrolyzes oxidized purine nucleoside triphosphates, such as 8-oxo-dGTP and 2-hydroxy-ATP, to monophosphates, thereby preventing the...; Region: MTH1; cd03427
553482006554	putative active site [active]
553482006555	nucleotide binding site [chemical binding]; other site
553482006556	nudix motif; other site
553482006557	putative metal binding site [ion binding]; other site
553482006558	HMMPfam hit to PF00293, NUDIX domain, score 4.3e-26
553482006559	PS00893 mutT domain signature.
553482006560	dTDP-D-glucose 4,6-dehydratase [Cell envelope biogenesis, outer membrane]; Region: RfbB; COG1088
553482006561	dTDP-D-glucose 4,6-dehydratase, extended (e) SDRs; Region: dTDP_GD_SDR_e; cd05246
553482006562	NAD binding site [chemical binding]; other site
553482006563	substrate binding site [chemical binding]; other site
553482006564	homodimer interface [polypeptide binding]; other site
553482006565	active site
553482006566	HMMPfam hit to PF04321, RmlD substrate binding domain, score 0.00023
553482006567	HMMPfam hit to PF01073, 3-beta hydroxysteroid dehydrogenase/i, score 1.1e-05
553482006568	HMMPfam hit to PF01370, NAD dependent epimerase/dehydratase f, score 8.6e-79
553482006569	HMMPfam hit to PF02719, Polysaccharide biosynthesis protein, score 0.0042
553482006570	HMMPfam hit to PF07993, Male sterility protein, score 4.8e-08
553482006571	dTDP-4-dehydrorhamnose 3,5-epimerase and related enzymes [Cell envelope biogenesis, outer membrane]; Region: RfbC; COG1898
553482006572	HMMPfam hit to PF00908, dTDP-4-dehydrorhamnose 3,5-epimerase, score 2.1e-14
553482006573	G1P_TT_short is the short form of glucose-1-phosphate thymidylyltransferase; Region: G1P_TT_short; cd02538
553482006574	glucose-1-phosphate thymidylyltransferase, short form; Region: rmlA; TIGR01207
553482006575	substrate binding site; other site
553482006576	tetramer interface; other site
553482006577	HMMPfam hit to PF00483, Nucleotidyl transferase, score 5e-119
553482006578	glycine oxidase ThiO; Region: thiamin_ThiO; TIGR02352
553482006579	HMMPfam hit to PF01266, FAD dependent oxidoreductase, score 2.8e-64
553482006580	Uncharacterized conserved protein [Function unknown]; Region: COG0327
553482006581	NIF3 (NGG1p interacting factor 3); Region: NIF3; pfam01784
553482006582	HMMPfam hit to PF01784, NIF3 (NGG1p interacting factor 3), score 7.3e-95
553482006583	Predicted SAM-dependent methyltransferase [General function prediction only]; Region: COG2384
553482006584	Family of unknown function (DUF633); Region: DUF633; pfam04816
553482006585	HMMPfam hit to PF04816, Family of unknown function (DUF633), score 8e-108
553482006586	Predicted EndoIII-related endonuclease [DNA replication, recombination, and repair]; Region: Nth; COG0177
553482006587	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
553482006588	minor groove reading motif; other site
553482006589	helix-hairpin-helix signature motif; other site
553482006590	substrate binding pocket [chemical binding]; other site
553482006591	active site
553482006592	iron-sulpphur binding domain in DNA-(apurinic or apyrimidinic site) lyase (subfamily of ENDO3); Region: FES; smart00525
553482006593	PS00290 Immunoglobulins and major histocompatibility complex proteins signature.
553482006594	HMMPfam hit to PF00633, Helix-hairpin-helix motif, score 5.8e-08
553482006595	Putative primosome component and related proteins [DNA replication, recombination, and repair]; Region: DnaD; COG3935
553482006596	Replication initiation and membrane attachment; Region: DnaB_2; pfam07261
553482006597	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
553482006598	active site
553482006599	HMMPfam hit to PF00156, Phosphoribosyl transferase domain, score 2.2e-46
553482006600	PS00103 Purine/pyrimidine phosphoribosyl transferases signature.
553482006601	conserved hypothetical protein; Region: TIGR02328
553482006602	Pyrimidine dimer DNA glycosylase; Region: Pyr_excise; pfam03013
553482006603	single-stranded-DNA-specific exonuclease RecJ; Region: recJ; TIGR00644
553482006604	DHH family; Region: DHH; pfam01368
553482006605	DHHA1 domain; Region: DHHA1; pfam02272
553482006606	Single-strand DNA-specific exonuclease, C terminal domain; Region: ssDNA-exonuc_C; cl11538
553482006607	HMMPfam hit to PF02272, DHHA1 domain, score 3e-12
553482006608	HMMPfam hit to PF01368, DHH family, score 1.2e-50
553482006609	Short-chain dehydrogenases of various substrate specificities [General function prediction only]; Region: DltE; COG0300
553482006610	classical (c) SDRs; Region: SDR_c; cd05233
553482006611	NAD(P) binding site [chemical binding]; other site
553482006612	active site
553482006613	HMMPfam hit to PF00106, short chain dehydrogenase, score 7e-23
553482006614	PS00061 Short-chain dehydrogenases/reductases family signature.
553482006615	ribonuclease Z; Region: RNase_Z; TIGR02651
553482006616	Galactose-1-phosphate uridyl transferase, N-terminal domain; Region: GalP_UDP_transf; pfam01087
553482006617	GTP-binding protein HflX; Region: GTP_HflX; TIGR03156
553482006618	GTP-binding GTPase N-terminal; Region: GTP-bdg_N; pfam13167
553482006619	HflX GTPase family; Region: HflX; cd01878
553482006620	G1 box; other site
553482006621	GTP/Mg2+ binding site [chemical binding]; other site
553482006622	Switch I region; other site
553482006623	G2 box; other site
553482006624	G3 box; other site
553482006625	Switch II region; other site
553482006626	G4 box; other site
553482006627	G5 box; other site
553482006628	HMMPfam hit to PF01926, GTPase of unknown function, score 1.2e-36
553482006629	PS00017 ATP/GTP-binding site motif A (P-loop).
553482006630	tRNA delta(2)-isopentenylpyrophosphate transferase; Reviewed; Region: miaA; PRK00091
553482006631	tRNA delta(2)-isopentenylpyrophosphate transferase [Translation, ribosomal structure and biogenesis]; Region: MiaA; COG0324
553482006632	HMMPfam hit to PF01715, IPP transferase, score 8.1e-66
553482006633	1 transmembrane helix predicted for SEQ1432 by TMHMM2.0 at aa 7-29
553482006634	PS00017 ATP/GTP-binding site motif A (P-loop).
553482006635	1 transmembrane helix predicted for SEQ1433 by TMHMM2.0 at aa 7-29
553482006636	Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates...; Region: NK; cl17190
553482006637	active site
553482006638	HMMPfam hit to PF00485, Phosphoribulokinase / Uridine kinase family, score 5.4e-05
553482006639	PS00017 ATP/GTP-binding site motif A (P-loop).
553482006640	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
553482006641	glycogen/starch/alpha-glucan phosphorylases; Region: P_ylase; TIGR02093
553482006642	HMMPfam hit to PF00343, Carbohydrate phosphorylase, score 4.3e-183
553482006643	PS00102 Phosphorylase pyridoxal-phosphate attachment site.
553482006644	PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site.
553482006645	4-alpha-glucanotransferase; Provisional; Region: PRK14508
553482006646	HMMPfam hit to PF02446, 4-alpha-glucanotransferase, score 2.2e-191
553482006647	Transcriptional regulators [Transcription]; Region: PurR; COG1609
553482006648	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
553482006649	DNA binding site [nucleotide binding]
553482006650	domain linker motif; other site
553482006651	Ligand-binding domain of uncharacterized transcription regulator ycjW which is a member of the LacI-GalR family repressors; Region: PBP1_ycjW_transcription_regulator_like; cd06294
553482006652	putative dimerization interface [polypeptide binding]; other site
553482006653	putative ligand binding site [chemical binding]; other site
553482006654	HMMPfam hit to PF00532, Periplasmic binding proteins and sugar b, score 4.9e-08
553482006655	HMMPfam hit to PF00356, Bacterial regulatory proteins, lacI fami, score 1.4e-08
553482006656	Predicted helix-turn-helix motif with score 2360.000, SD 7.22 at aa 2-23, sequence VTIKDVALKAGVNPSTVSRVLK
553482006657	Maltose-binding periplasmic proteins/domains [Carbohydrate transport and metabolism]; Region: MalE; COG2182
553482006658	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
553482006659	HMMPfam hit to PF01547, Bacterial extracellular solute-binding prot, score 5.8e-26
553482006660	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482006661	PS00017 ATP/GTP-binding site motif A (P-loop).
553482006662	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
553482006663	dimer interface [polypeptide binding]; other site
553482006664	conserved gate region; other site
553482006665	ABC-ATPase subunit interface; other site
553482006666	8 transmembrane helices predicted for SEQ1439 by TMHMM2.0 at aa 47-69, 98-120, 162-184, 222-244, 257-279, 309-331, 352-374 and 419-441
553482006667	HMMPfam hit to PF00528, Binding-protein-dependent transport syst, score 1.5e-12
553482006668	PS00402 Binding-protein-dependent transport systems inner membrane comp. sign.
553482006669	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
553482006670	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
553482006671	dimer interface [polypeptide binding]; other site
553482006672	conserved gate region; other site
553482006673	putative PBP binding loops; other site
553482006674	ABC-ATPase subunit interface; other site
553482006675	6 transmembrane helices predicted for SEQ1440 by TMHMM2.0 at aa 9-31, 75-97, 110-129, 139-161, 182-204 and 242-264
553482006676	HMMPfam hit to PF00528, Binding-protein-dependent transport syst, score 2e-17
553482006677	PS00041 Bacterial regulatory proteins, araC family signature.
553482006678	PS00402 Binding-protein-dependent transport systems inner membrane comp. sign.
553482006679	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
553482006680	Helix-turn-helix domain; Region: HTH_28; pfam13518
553482006681	Predicted helix-turn-helix motif with score 1140.000, SD 3.07 at aa 19-40, sequence KSIKCLSEKFSIAESDLKYMIR
553482006682	HMMPfam hit to PF01527, Transposase, score 0.00062
553482006683	HMMPfam hit to PF02178, no description, score 0.21
553482006684	putative transposase OrfB; Reviewed; Region: PHA02517
553482006685	HTH-like domain; Region: HTH_21; pfam13276
553482006686	Integrase core domain; Region: rve; pfam00665
553482006687	Integrase core domain; Region: rve_2; pfam13333
553482006688	HMMPfam hit to PF00665, Integrase core domain, score 9.5e-38
553482006689	Predicted integral membrane protein [Function unknown]; Region: COG5521
553482006690	4 transmembrane helices predicted for SEQ1443 by TMHMM2.0 at aa 27-49, 176-198, 219-241 and 245-264
553482006691	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
553482006692	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
553482006693	dimer interface [polypeptide binding]; other site
553482006694	conserved gate region; other site
553482006695	putative PBP binding loops; other site
553482006696	ABC-ATPase subunit interface; other site
553482006697	HMMPfam hit to PF00528, Binding-protein-dependent transport syst, score 4.8e-24
553482006698	5 transmembrane helices predicted for SEQ1444 by TMHMM2.0 at aa 21-43, 81-103, 115-137, 142-164 and 250-272
553482006699	PS00402 Binding-protein-dependent transport systems inner membrane comp. sign.
553482006700	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
553482006701	dimer interface [polypeptide binding]; other site
553482006702	conserved gate region; other site
553482006703	putative PBP binding loops; other site
553482006704	ABC-ATPase subunit interface; other site
553482006705	HMMPfam hit to PF00528, Binding-protein-dependent transport syst, score 7.5e-20
553482006706	8 transmembrane helices predicted for SEQ1445 by TMHMM2.0 at aa 34-56, 71-93, 127-149, 196-218, 230-252, 291-313, 338-357 and 401-423
553482006707	PS00402 Binding-protein-dependent transport systems inner membrane comp. sign.
553482006708	Alpha amylase catalytic domain found in maltogenic amylases, cyclodextrin glycosyltransferase, and related proteins; Region: AmyAc_AmyMalt_CGTase_like; cd11320
553482006709	Glycosidases [Carbohydrate transport and metabolism]; Region: AmyA; COG0366
553482006710	Ca binding site [ion binding]; other site
553482006711	active site
553482006712	catalytic site [active]
553482006713	Aamy_C domain; Region: Aamy_C; smart00632
553482006714	IPT domain (domain D) of cyclodextrin glycosyltransferase (CGTase) and similar enzymes. These enzymes are involved in the enzymatic hydrolysis of alpha-1,4 linkages of starch polymers and belong to the glycosyl hydrolase family 13. Most consist of three...; Region: IPT_CGTD; cd00604
553482006715	The family 20 carbohydrate-binding module (CBM20), also known as the starch-binding domain, is found in a large number of starch degrading enzymes including alpha-amylase, beta-amylase, glucoamylase, and CGTase (cyclodextrin glucanotransferase). CBM20 is...; Region: CBM20; cl15347
553482006716	starch-binding site 2 [chemical binding]; other site
553482006717	starch-binding site 1 [chemical binding]; other site
553482006718	HMMPfam hit to PF00686, Starch binding domain, score 1.1e-15
553482006719	HMMPfam hit to PF01833, IPT/TIG domain, score 1.4e-10
553482006720	HMMPfam hit to PF02806, Alpha amylase, C-terminal all-beta do, score 1.1e-25
553482006721	HMMPfam hit to PF00128, Alpha amylase, catalytic domain, score 7.9e-110
553482006722	PS00962 Ribosomal protein S2 signature 1.
553482006723	maltodextrin glucosidase; Provisional; Region: PRK10785
553482006724	N-terminal Early set domain associated with the catalytic domain of cyclomaltodextrinase and pullulan-degrading enzymes; Region: E_set_CDase_PDE_N; cd02857
553482006725	homodimer interface [polypeptide binding]; other site
553482006726	Alpha amylase catalytic domain found in cyclomaltodextrinases and related proteins; Region: AmyAc_CMD; cd11338
553482006727	active site
553482006728	homodimer interface [polypeptide binding]; other site
553482006729	catalytic site [active]
553482006730	HMMPfam hit to PF00128, Alpha amylase, catalytic domain, score 1.6e-91
553482006731	HMMPfam hit to PF02903, Alpha amylase, N-terminal ig-like dom, score 3.7e-10
553482006732	Maltose-binding periplasmic proteins/domains [Carbohydrate transport and metabolism]; Region: MalE; COG2182
553482006733	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
553482006734	HMMPfam hit to PF01547, Bacterial extracellular solute-binding prot, score 2.8e-39
553482006735	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482006736	Esterase/lipase [Lipid metabolism]; Region: Aes; COG0657
553482006737	Protein of unknown function (DUF2424); Region: DUF2424; pfam10340
553482006738	HMMPfam hit to PF07859, alpha/beta hydrolase fold, score 4e-18
553482006739	1 transmembrane helix predicted for SEQ1449 by TMHMM2.0 at aa 5-22
553482006740	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein) [Cell envelope biogenesis, outer membrane]; Region: DltD; COG3966
553482006741	DltD N-terminal region; Region: DltD_N; pfam04915
553482006742	DltD central region; Region: DltD_M; pfam04918
553482006743	DltD C-terminal region; Region: DltD_C; pfam04914
553482006744	HMMPfam hit to PF04914, DltD C-terminal region, score 1.8e-79
553482006745	HMMPfam hit to PF04918, DltD central region, score 3e-70
553482006746	HMMPfam hit to PF04915, DltD N-terminal region, score 3.3e-38
553482006747	1 transmembrane helix predicted for SEQ1450 by TMHMM2.0 at aa 5-27
553482006748	D-alanine--poly(phosphoribitol) ligase subunit 2; Validated; Region: PRK05087
553482006749	D-alanyl-lipoteichoic acid biosynthesis protein DltB; Region: LTA_dltB; TIGR04091
553482006750	9 transmembrane helices predicted for SEQ1452 by TMHMM2.0 at aa 13-35, 40-57, 64-81, 91-113, 118-136, 193-215, 236-258, 336-358 and 379-401
553482006751	HMMPfam hit to PF03062, MBOAT family, score 2.6e-96
553482006752	D-alanine--poly(phosphoribitol) ligase subunit 1; Provisional; Region: PRK04813
553482006753	D-alanine:D-alanyl carrier protein ligase (DltA); Region: DltA; cd05945
553482006754	acyl-activating enzyme (AAE) consensus motif; other site
553482006755	AMP binding site [chemical binding]; other site
553482006756	PS00455 AMP-binding domain signature.
553482006757	excinuclease ABC subunit B; Provisional; Region: PRK05298
553482006758	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
553482006759	ATP binding site [chemical binding]; other site
553482006760	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
553482006761	nucleotide binding region [chemical binding]; other site
553482006762	ATP-binding site [chemical binding]; other site
553482006763	Ultra-violet resistance protein B; Region: UvrB; pfam12344
553482006764	HMMPfam hit to PF02151, UvrB/uvrC motif, score 1.6e-08
553482006765	HMMPfam hit to PF00271, Helicase conserved C-terminal domain, score 7.7e-20
553482006766	HMMPfam hit to PF04851, Type III restriction enzyme, res subunit, score 8.7e-06
553482006767	PS00017 ATP/GTP-binding site motif A (P-loop).
553482006768	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
553482006769	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
553482006770	substrate binding pocket [chemical binding]; other site
553482006771	membrane-bound complex binding site; other site
553482006772	hinge residues; other site
553482006773	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
553482006774	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
553482006775	substrate binding pocket [chemical binding]; other site
553482006776	membrane-bound complex binding site; other site
553482006777	hinge residues; other site
553482006778	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
553482006779	dimer interface [polypeptide binding]; other site
553482006780	conserved gate region; other site
553482006781	putative PBP binding loops; other site
553482006782	ABC-ATPase subunit interface; other site
553482006783	HMMPfam hit to PF00497, Bacterial extracellular solute-binding p, score 2.2e-75
553482006784	HMMPfam hit to PF00497, Bacterial extracellular solute-binding p, score 4.8e-74
553482006785	HMMPfam hit to PF00528, Binding-protein-dependent transport syst, score 1.3e-28
553482006786	4 transmembrane helices predicted for SEQ1455 by TMHMM2.0 at aa 518-540, 553-575, 595-617 and 691-713
553482006787	PS00402 Binding-protein-dependent transport systems inner membrane comp. sign.
553482006788	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
553482006789	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
553482006790	Walker A/P-loop; other site
553482006791	ATP binding site [chemical binding]; other site
553482006792	Q-loop/lid; other site
553482006793	ABC transporter signature motif; other site
553482006794	Walker B; other site
553482006795	D-loop; other site
553482006796	H-loop/switch region; other site
553482006797	HMMPfam hit to PF00005, ABC transporter, score 7.4e-66
553482006798	PS00017 ATP/GTP-binding site motif A (P-loop).
553482006799	PS00211 ABC transporters family signature.
553482006800	Phosphotransferase system cellobiose-specific component IIC [Carbohydrate transport and metabolism]; Region: CelB; COG1455
553482006801	cellobiose phosphotransferase system IIC component; Reviewed; Region: celD; PRK09592
553482006802	11 transmembrane helices predicted for SEQ1457 by TMHMM2.0 at aa 21-43, 74-96, 103-125, 167-189, 209-231, 251-273, 280-299, 319-341, 371-393, 398-420 and 425-447
553482006803	HMMPfam hit to PF02378, Phosphotransferase system, EIIC, score 1.5e-62
553482006804	START/RHO_alpha_C/PITP/Bet_v1/CoxG/CalC (SRPBCC) ligand-binding domain superfamily; Region: SRPBCC; cd07812
553482006805	hydrophobic ligand binding site; other site
553482006806	PTS_IIA, PTS system, lactose/cellobiose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_lac; cd00215
553482006807	active site
553482006808	methionine cluster; other site
553482006809	phosphorylation site [posttranslational modification]
553482006810	metal binding site [ion binding]; metal-binding site
553482006811	HMMPfam hit to PF02255, PTS system, Lactose/Cellobiose specific IIA, score 6.4e-38
553482006812	PTS_IIB_chitobiose_lichenan: subunit IIB of enzyme II (EII) of the N,N-diacetylchitobiose-specific and lichenan-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In these systems, EII is either a lichenan- or an N; Region: PTS_IIB_chitobiose_lichenan; cd05564
553482006813	active site
553482006814	P-loop; other site
553482006815	phosphorylation site [posttranslational modification]
553482006816	HMMPfam hit to PF02302, PTS system, Lactose/Cellobiose specific IIB, score 2.3e-41
553482006817	Transcriptional antiterminator [Transcription]; Region: BglG; COG3711
553482006818	HTH domain; Region: HTH_11; pfam08279
553482006819	Mga helix-turn-helix domain; Region: Mga; pfam05043
553482006820	PRD domain; Region: PRD; pfam00874
553482006821	PRD domain; Region: PRD; pfam00874
553482006822	PTS_IIB_bgl_like: the PTS (phosphotransferase system) IIB domain of a family of sensory systems composed of a membrane-bound sugar-sensor (similar to BglF) and a transcription antiterminator (similar to BglG) which regulate expression of genes involved...; Region: PTS_IIB_bgl_like; cd05568
553482006823	active site
553482006824	P-loop; other site
553482006825	phosphorylation site [posttranslational modification]
553482006826	Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type) [Carbohydrate transport and metabolism / Signal transduction mechanisms]; Region: PtsN; COG1762
553482006827	active site
553482006828	phosphorylation site [posttranslational modification]
553482006829	HMMPfam hit to PF00874, PRD domain, score 5.2e-16
553482006830	HMMPfam hit to PF00874, PRD domain, score 2.9e-16
553482006831	HMMPfam hit to PF05043, Mga helix-turn-helix domain, score 1.1e-21
553482006832	Predicted helix-turn-helix motif with score 1309.000, SD 3.65 at aa 114-135, sequence WDFEELCQELYISRTTLNHVLA
553482006833	HMMPfam hit to PF08279, HTH domain, score 6.1e-16
553482006834	Predicted helix-turn-helix motif with score 1653.000, SD 4.82 at aa 21-42, sequence VSSATLAKAIGMSDRTVRKYLK
553482006835	Uncharacterized conserved protein [Function unknown]; Region: COG3589
553482006836	Bacterial protein of unknown function (DUF871); Region: DUF871; pfam05913
553482006837	HMMPfam hit to PF05913, Bacterial protein of unknown function (DUF87, score 2e-186
553482006838	Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase [Carbohydrate transport and metabolism]; Region: BglB; COG2723
553482006839	beta-galactosidase; Region: BGL; TIGR03356
553482006840	HMMPfam hit to PF00232, Glycosyl hydrolase family, score 1.2e-112
553482006841	Nicotinamide mononucleotide transporter; Region: NMN_transporter; pfam04973
553482006842	HMMPfam hit to PF04973, Nicotinamide mononucleotide transport, score 5.4e-43
553482006843	8 transmembrane helices predicted for SEQ1464 by TMHMM2.0 at aa 12-29, 33-51, 56-78, 82-101, 122-139, 144-163, 170-192 and 197-219
553482006844	GTPase CgtA; Reviewed; Region: obgE; PRK12297
553482006845	GTP1/OBG; Region: GTP1_OBG; pfam01018
553482006846	Obg GTPase; Region: Obg; cd01898
553482006847	G1 box; other site
553482006848	GTP/Mg2+ binding site [chemical binding]; other site
553482006849	Switch I region; other site
553482006850	G2 box; other site
553482006851	G3 box; other site
553482006852	Switch II region; other site
553482006853	G4 box; other site
553482006854	G5 box; other site
553482006855	Domain of unknown function (DUF1967); Region: DUF1967; pfam09269
553482006856	HMMPfam hit to PF01926, GTPase of unknown function, score 3.6e-40
553482006857	PS00017 ATP/GTP-binding site motif A (P-loop).
553482006858	HMMPfam hit to PF01018, GTP1/OBG, score 9e-83
553482006859	CDS contains a 408 bp internal deletion. Similar to Streptococcus thermophilus aminopeptidase PepS UniProt:Q9X4A7 (EMBL:AF102860 (413 aa) fasta scores: E()=4.9e-47, 54.237% id in 236 aa
553482006860	HMMPfam hit to PF02073, Thermophilic metalloprotease (M29), score 2.3e-28
553482006861	16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases [Translation, ribosomal structure and biogenesis]; Region: RsuA; COG1187
553482006862	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
553482006863	RNA binding surface [nucleotide binding]; other site
553482006864	Pseudouridine synthase, Escherichia coli RsuA like; Region: PseudoU_synth_RsuA; cd02553
553482006865	active site
553482006866	uracil binding [chemical binding]; other site
553482006867	HMMPfam hit to PF00849, RNA pseudouridylate synthase, score 3.4e-19
553482006868	PS01149 Rsu family of pseudouridine synthase signature.
553482006869	HMMPfam hit to PF01479, S4 domain, score 1.4e-11
553482006870	Predicted thioesterase [General function prediction only]; Region: COG5496
553482006871	benzoate transport; Region: 2A0115; TIGR00895
553482006872	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
553482006873	putative substrate translocation pore; other site
553482006874	HMMPfam hit to PF00083, Sugar (and other) transporter, score 7.8e-06
553482006875	12 transmembrane helices predicted for SEQ1470 by TMHMM2.0 at aa 13-35, 50-69, 82-104, 108-130, 137-159, 163-185, 223-245, 260-279, 286-305, 311-333, 346-368 and 372-394
553482006876	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4868
553482006877	hypothetical protein; Provisional; Region: PRK13663
553482006878	PS00017 ATP/GTP-binding site motif A (P-loop).
553482006879	PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria.  Although orthologs of PaaI exist in archaea and eukaryotes, their function has not...; Region: PaaI_thioesterase; cd03443
553482006880	Thioesterase-like superfamily; Region: 4HBT_3; pfam13622
553482006881	CoenzymeA binding site [chemical binding]; other site
553482006882	subunit interaction site [polypeptide binding]; other site
553482006883	PHB binding site; other site
553482006884	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
553482006885	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
553482006886	HMMPfam hit to PF00583, Acetyltransferase (GNAT) family, score 0.00091
553482006887	Predicted hydrolase (HAD superfamily) [General function prediction only]; Region: COG1011
553482006888	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
553482006889	active site
553482006890	motif I; other site
553482006891	motif II; other site
553482006892	HMMPfam hit to PF00702, haloacid dehalogenase-like hydrolase, score 6.9e-26
553482006893	2 transmembrane helices predicted for SEQ1476 by TMHMM2.0 at aa 72-89 and 94-113
553482006894	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
553482006895	Helix-turn-helix domain; Region: HTH_28; pfam13518
553482006896	Predicted helix-turn-helix motif with score 1140.000, SD 3.07 at aa 19-40, sequence KSIKCLSEKFSIAESDLKYMIR
553482006897	HMMPfam hit to PF01527, Transposase, score 0.00062
553482006898	HMMPfam hit to PF02178, no description, score 0.21
553482006899	putative transposase OrfB; Reviewed; Region: PHA02517
553482006900	HTH-like domain; Region: HTH_21; pfam13276
553482006901	Integrase core domain; Region: rve; pfam00665
553482006902	Integrase core domain; Region: rve_2; pfam13333
553482006903	HMMPfam hit to PF00665, Integrase core domain, score 8.8e-38
553482006904	CDS contains a frameshift around codon 199. Similar to Streptococcus agalactiae serotype V hyaluronidase UniProt:Q8DZB2 (EMBL:AE014246 (1072 aa) fasta scores: E()=6e-166, 45.253% id in 1085 aa, and to Streptococcus agalactiae serotype III hyaluronidase HylB UniProt:Q53591 (EMBL:AL766849 (984 aa) fasta scores: E()=8.3e-163, 47.197% id in 981 aa
553482006905	HMMPfam hit to PF02884, Polysaccharide lyase family 8, C-terminal b, score 0.00027
553482006906	HMMPfam hit to PF02278, Polysaccharide lyase family 8, super-sandwi, score 2.3e-120
553482006907	HMMPfam hit to PF08124, Polysaccharide lyase family 8, N terminal a, score 1.3e-155
553482006908	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482006909	2-keto-3-deoxy-6-phosphogluconate aldolase [Carbohydrate transport and metabolism]; Region: Eda; COG0800
553482006910	KDPG and KHG aldolase; Region: KDPG_aldolase; cd00452
553482006911	active site
553482006912	intersubunit interface [polypeptide binding]; other site
553482006913	catalytic residue [active]
553482006914	HMMPfam hit to PF01081, KDPG and KHG aldolase, score 2.1e-28
553482006915	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
553482006916	2-keto-3-deoxygluconate kinase (KdgK) phosphorylates 2-keto-3-deoxygluconate (KDG) to form 2-keto-3-deoxy-6-phosphogluconate (KDGP). KDG is the common intermediate product, that allows organisms to channel D-glucuronate and/or D-galacturinate into the...; Region: KdgK; cd01166
553482006917	substrate binding site [chemical binding]; other site
553482006918	ATP binding site [chemical binding]; other site
553482006919	HMMPfam hit to PF00294, pfkB family carbohydrate kinase, score 1.2e-10
553482006920	hypothetical protein; Provisional; Region: PRK09273
553482006921	Ribose 5-phosphate isomerase RpiB [Carbohydrate transport and metabolism]; Region: RpiB; COG0698
553482006922	Ribose-5-phosphate isomerase; Region: DUF3666; pfam12408
553482006923	HMMPfam hit to PF06562, ribose 5-phosphate isomerase (DUF11, score 1.1e-152
553482006924	gluconate 5-dehydrogenase; Provisional; Region: PRK07097
553482006925	gluconate 5-dehydrogenase (Ga5DH)-like, classical (c) SDRs; Region: Ga5DH-like_SDR_c; cd05347
553482006926	NADP binding site [chemical binding]; other site
553482006927	homodimer interface [polypeptide binding]; other site
553482006928	active site
553482006929	HMMPfam hit to PF00106, short chain dehydrogenase, score 2.4e-26
553482006930	PS00061 Short-chain dehydrogenases/reductases family signature.
553482006931	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cd00006
553482006932	active pocket/dimerization site; other site
553482006933	active site
553482006934	phosphorylation site [posttranslational modification]
553482006935	HMMPfam hit to PF03610, PTS system fructose IIA component, score 1.5e-34
553482006936	Glycosyl Hydrolase Family 88; Region: Glyco_hydro_88; pfam07470
553482006937	HMMPfam hit to PF07470, Glycosyl Hydrolase Family, score 2e-120
553482006938	PTS_IIB, PTS system, Mannose/sorbose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_man; cd00001
553482006939	active site
553482006940	phosphorylation site [posttranslational modification]
553482006941	HMMPfam hit to PF03830, PTS system sorbose subfamily IIB componen, score 1.8e-74
553482006942	Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIC [Carbohydrate transport and metabolism]; Region: ManY; COG3715
553482006943	HMMPfam hit to PF03609, PTS system sorbose-specific iic component, score 1.1e-97
553482006944	6 transmembrane helices predicted for SEQ1488 by TMHMM2.0 at aa 5-27, 32-54, 97-119, 140-162, 177-199 and 211-233
553482006945	Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IID [Carbohydrate transport and metabolism]; Region: ManZ; COG3716
553482006946	HMMPfam hit to PF03613, PTS system mannose/fructose/sorbose family I, score 2.1e-128
553482006947	5 transmembrane helices predicted for SEQ1489 by TMHMM2.0 at aa 100-122, 137-159, 180-202, 228-245 and 250-272
553482006948	Transcriptional regulators [Transcription]; Region: PurR; COG1609
553482006949	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
553482006950	DNA binding site [nucleotide binding]
553482006951	domain linker motif; other site
553482006952	Ligand-binding domain of DNA transcription repressor RegR and other putative regulators such as KdgR and EndR; Region: PBP1_RegR_EndR_KdgR_like; cd06283
553482006953	putative dimerization interface [polypeptide binding]; other site
553482006954	putative ligand binding site [chemical binding]; other site
553482006955	HMMPfam hit to PF00356, Bacterial regulatory proteins, lacI fami, score 1.9e-05
553482006956	Predicted helix-turn-helix motif with score 1618.000, SD 4.70 at aa 5-26, sequence VTINDIADLAKTSKTTVSFYLN
553482006957	HMMPfam hit to PF00532, Periplasmic binding proteins and sugar b, score 7.1e-06
553482006958	CDS contains a nonsense mutation (ochre) in comparison to SZO06550
553482006959	CDS contains a nonsense mutation (opal) in comparison to SZO06550
553482006960	Cation transport ATPase [Inorganic ion transport and metabolism]; Region: MgtA; COG0474
553482006961	Cation transporter/ATPase, N-terminus; Region: Cation_ATPase_N; smart00831
553482006962	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
553482006963	Putative hydrolase of sodium-potassium ATPase alpha subunit; Region: Hydrolase_like2; pfam13246
553482006964	haloacid dehalogenase-like hydrolase; Region: HAD; pfam12710
553482006965	Cation transporting ATPase, C-terminus; Region: Cation_ATPase_C; pfam00689
553482006966	HMMPfam hit to PF00689, Cation transporting ATPase, C-terminu, score 3.4e-19
553482006967	8 transmembrane helices predicted for SEQ1497 by TMHMM2.0 at aa 65-82, 86-105, 253-275, 285-307, 682-704, 756-778, 827-849 and 859-881
553482006968	HMMPfam hit to PF00702, haloacid dehalogenase-like hydrolase, score 3.7e-19
553482006969	PS00154 E1-E2 ATPases phosphorylation site.
553482006970	HMMPfam hit to PF00122, E1-E2 ATPase, score 1e-100
553482006971	HMMPfam hit to PF00690, Cation transporter/ATPase, N-terminus, score 2.4e-27
553482006972	Domain of unknown function (DUF1934); Region: DUF1934; pfam09148
553482006973	HD superfamily phosphohydrolases [General function prediction only]; Region: COG1078
553482006974	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
553482006975	Zn2+ binding site [ion binding]; other site
553482006976	Mg2+ binding site [ion binding]; other site
553482006977	HMMPfam hit to PF01966, HD domain, score 9.4e-09
553482006978	sugar phosphate phosphatase; Provisional; Region: PRK10513
553482006979	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
553482006980	active site
553482006981	motif I; other site
553482006982	motif II; other site
553482006983	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
553482006984	HMMPfam hit to PF05116, Sucrose-6F-phosphate phosphohydrolase, score 7.9e-06
553482006985	HMMPfam hit to PF00702, haloacid dehalogenase-like hydrolase, score 0.0018
553482006986	PS01228 Hypothetical cof family signature 1.
553482006987	HMMPfam hit to PF08282, haloacid dehalogenase-like hydrolase, score 2.4e-94
553482006988	PS01229 Hypothetical cof family signature 2.
553482006989	FemAB family; Region: FemAB; pfam02388
553482006990	Acetyltransferase (GNAT) domain; Region: Acetyltransf_6; pfam13480
553482006991	HMMPfam hit to PF02388, FemAB family, score 7.5e-12
553482006992	FemAB family; Region: FemAB; pfam02388
553482006993	Acetyltransferase (GNAT) domain; Region: Acetyltransf_6; pfam13480
553482006994	HMMPfam hit to PF02388, FemAB family, score 2.7e-120
553482006995	triosephosphate isomerase; Provisional; Region: PRK14567
553482006996	Triosephosphate isomerase (TIM) is a glycolytic enzyme that catalyzes the interconversion of dihydroxyacetone phosphate and D-glyceraldehyde-3-phosphate. The reaction is very efficient and requires neither cofactors nor metal ions. TIM, usually...; Region: TIM; cd00311
553482006997	substrate binding site [chemical binding]; other site
553482006998	dimer interface [polypeptide binding]; other site
553482006999	catalytic triad [active]
553482007000	HMMPfam hit to PF00121, Triosephosphate isomerase, score 2.7e-138
553482007001	PS00171 Triosephosphate isomerase active site.
553482007002	elongation factor Tu; Reviewed; Region: PRK00049
553482007003	Elongation Factor Tu (EF-Tu) GTP-binding proteins; Region: EF_Tu; cd01884
553482007004	G1 box; other site
553482007005	GEF interaction site [polypeptide binding]; other site
553482007006	GTP/Mg2+ binding site [chemical binding]; other site
553482007007	Switch I region; other site
553482007008	G2 box; other site
553482007009	G3 box; other site
553482007010	Switch II region; other site
553482007011	G4 box; other site
553482007012	G5 box; other site
553482007013	EFTU_II: Elongation factor Tu domain II. Elongation factors Tu (EF-Tu) are three-domain GTPases with an essential function in the elongation phase of mRNA translation. The GTPase center of EF-Tu is in the N-terminal domain (domain I), also known as the...; Region: EFTU_II; cd03697
553482007014	Domain III of elongation factor (EF) Tu. Ef-Tu consists of three structural domains, designated I, II and III. Domain III adopts a beta barrel structure. Domain III is involved in binding to both charged tRNA and binding to elongation factor Ts (EF-Ts); Region: EFTU_III; cd03707
553482007015	Antibiotic Binding Site [chemical binding]; other site
553482007016	HMMPfam hit to PF03143, Elongation factor Tu C-terminal domain, score 3.6e-59
553482007017	HMMPfam hit to PF03144, Elongation factor Tu domain, score 1.1e-23
553482007018	HMMPfam hit to PF00009, Elongation factor Tu GTP binding domain, score 5.6e-101
553482007019	PS00301 GTP-binding elongation factors signature.
553482007020	PS00017 ATP/GTP-binding site motif A (P-loop).
553482007021	Viral enhancin protein; Region: Enhancin; pfam03272
553482007022	Viral enhancin protein; Region: Enhancin; pfam03272
553482007023	Viral enhancin protein; Region: Enhancin; pfam03272
553482007024	CDS contains a frameshift around codon 108. Similar to Streptococcus agalactiae hypothetical protein UniProt:Q3D6L8 (EMBL:AAJR01000060 (315 aa) fasta scores: E()=4.9e-23, 32.320% id in 362 aa
553482007025	1 transmembrane helix predicted for SEQ1508 by TMHMM2.0 at aa 20-42
553482007026	RNA polymerase sigma factor, SigM family; Region: SigM_subfam; TIGR02950
553482007027	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
553482007028	DNA binding residues [nucleotide binding]
553482007029	HMMPfam hit to PF04545, Sigma-70, region, score 6.4e-08
553482007030	HMMPfam hit to PF08281, Sigma-70, region, score 3.8e-16
553482007031	Protein of unknown function (DUF4237); Region: DUF4237; pfam14021
553482007032	bifunctional N-succinyldiaminopimelate-aminotransferase/acetylornithine transaminase protein; Reviewed; Region: argD; PRK05093
553482007033	gene remnant. C-terminus is similar to the C-terminal region of Listeria monocytogenes serotype 4b hypothetical protein UniProt:Q724Y9 (EMBL:AE017262 (236 aa) fasta scores: E()=9.8e-26, 45.745% id in 188 aa
553482007034	putative transposase OrfB; Reviewed; Region: PHA02517
553482007035	HTH-like domain; Region: HTH_21; pfam13276
553482007036	Integrase core domain; Region: rve; pfam00665
553482007037	Integrase core domain; Region: rve_2; pfam13333
553482007038	HMMPfam hit to PF00665, Integrase core domain, score 8.8e-38
553482007039	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
553482007040	Helix-turn-helix domain; Region: HTH_28; pfam13518
553482007041	Homeodomain-like domain; Region: HTH_32; pfam13565
553482007042	HMMPfam hit to PF02178, no description, score 0.21
553482007043	Predicted helix-turn-helix motif with score 1140.000, SD 3.07 at aa 19-40, sequence KSIKCLSEKFSIAESDLKYMIR
553482007044	Predicted hydrolase (HAD superfamily) [General function prediction only]; Region: COG1011
553482007045	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
553482007046	motif II; other site
553482007047	HMMPfam hit to PF00702, haloacid dehalogenase-like hydrolase, score 3.9e-23
553482007048	CDS contains a frameshift after codon 106. Frameshift occurs at a poly T hexamer. Similar to Streptococcus agalactiae serotype Ia drug:H+ antiporter-2 (Dha2) family protein UniProt:Q3JZI6 (EMBL:CP000114 (499 aa) fasta scores: E()=8.1e-121, 68.852% id in 488 aa
553482007049	11 transmembrane helices predicted for SEQ1523 by TMHMM2.0 at aa 10-32, 39-61, 71-91, 112-134, 138-155, 175-197, 212-234, 241-260, 270-292, 313-330 and 358-380
553482007050	3 transmembrane helices predicted for SEQ1524 by TMHMM2.0 at aa 17-39, 54-73 and 85-107
553482007051	lysyl-tRNA synthetase; Reviewed; Region: lysS; PRK00484
553482007052	LysRS_N: N-terminal, anticodon recognition domain of lysyl-tRNA synthetases (LysRS). These enzymes are homodimeric class 2b aminoacyl-tRNA synthetases (aaRSs). This domain is a beta-barrel domain (OB fold) involved in binding the tRNA anticodon stem-loop; Region: LysRS_N; cd04322
553482007053	dimer interface [polypeptide binding]; other site
553482007054	putative anticodon binding site; other site
553482007055	Lys_tRNA synthetase (LysRS) class II core domain. Class II LysRS is a dimer which attaches a lysine to the 3' OH group of ribose of the appropriate tRNA. Its assignment to class II aaRS is based upon its structure and the presence of three...; Region: LysRS_core; cd00775
553482007056	motif 1; other site
553482007057	active site
553482007058	motif 2; other site
553482007059	motif 3; other site
553482007060	HMMPfam hit to PF01336, OB-fold nucleic acid binding domain, score 1.1e-17
553482007061	HMMPfam hit to PF00152, tRNA synthetases class II (D, K and N), score 6.9e-119
553482007062	PS00179 Aminoacyl-transfer RNA synthetases class-II signature 1.
553482007063	PS00339 Aminoacyl-transfer RNA synthetases class-II signature 2.
553482007064	1 transmembrane helix predicted for SEQ1527 by TMHMM2.0 at aa 13-35
553482007065	gene remnant. Fragment contains a nonsense mutation (ochre) after codon 43. Similar to Streptococcus thermophilus transposase Tnpsth1 UniProt:Q5M4U1 (EMBL:CP000023 (289 aa) fasta scores: E()=7.4e-07, 50.847% id in 59 aa
553482007066	Uncharacterized protein conserved in bacteria (DUF2128); Region: DUF2128; pfam09901
553482007067	Collagenase and related proteases [Posttranslational modification, protein turnover, chaperones]; Region: COG0826
553482007068	Peptidase family U32; Region: Peptidase_U32; pfam01136
553482007069	HMMPfam hit to PF01136, Peptidase family U32, score 1.3e-131
553482007070	PS01276 Peptidase family U32 signature.
553482007071	Collagenase and related proteases [Posttranslational modification, protein turnover, chaperones]; Region: COG0826
553482007072	Peptidase family U32; Region: Peptidase_U32; pfam01136
553482007073	HMMPfam hit to PF01136, Peptidase family U32, score 1.1e-76
553482007074	Helix-turn-helix domain; Region: HTH_28; pfam13518
553482007075	Winged helix-turn helix; Region: HTH_29; pfam13551
553482007076	Homeodomain-like domain; Region: HTH_32; pfam13565
553482007077	Integrase core domain; Region: rve; pfam00665
553482007078	HMMPfam hit to PF00665, Integrase core domain, score 6.4e-17
553482007079	PS00017 ATP/GTP-binding site motif A (P-loop).
553482007080	Protein of unknown function (DUF3270); Region: DUF3270; pfam11674
553482007081	2 transmembrane helices predicted for SEQ1534 by TMHMM2.0 at aa 60-82 and 87-109
553482007082	YtxH-like protein; Region: YtxH; pfam12732
553482007083	Uncharacterized protein containing a divergent version of the methyl-accepting chemotaxis-like domain [General function prediction only]; Region: COG4768
553482007084	HMMPfam hit to PF06103, Bacterial protein of unknown function (DUF94, score 1.5e-45
553482007085	1 transmembrane helix predicted for SEQ1536 by TMHMM2.0 at aa 4-26
553482007086	prolipoprotein diacylglyceryl transferase; Reviewed; Region: PRK12437
553482007087	HMMPfam hit to PF01790, Prolipoprotein diacylglyceryl transferase, score 2.5e-133
553482007088	5 transmembrane helices predicted for SEQ1537 by TMHMM2.0 at aa 15-33, 46-68, 83-105, 165-187 and 224-246
553482007089	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482007090	PS01311 Prolipoprotein diacylglyceryl transferase signature.
553482007091	HPr Serine kinase N terminus; Region: Hpr_kinase_N; pfam02603
553482007092	HPr kinase/phosphorylase; Provisional; Region: PRK05428
553482007093	HprK/P, the bifunctional histidine-containing protein kinase/phosphatase, controls the phosphorylation state of the phosphocarrier protein HPr and regulates the utilization of carbon sources by gram-positive bacteria. It catalyzes both the ATP-dependent...; Region: HprK_C; cd01918
553482007094	Hpr binding site; other site
553482007095	active site
553482007096	homohexamer subunit interaction site [polypeptide binding]; other site
553482007097	HMMPfam hit to PF07475, HPr Serine kinase C-terminus, score 2.6e-70
553482007098	PS00017 ATP/GTP-binding site motif A (P-loop).
553482007099	HMMPfam hit to PF02603, HPr Serine kinase N terminus, score 3.7e-28
553482007100	Putative stress-responsive transcriptional regulator [Transcription / Signal transduction mechanisms]; Region: PspC; COG1983
553482007101	HMMPfam hit to PF04024, PspC domain, score 1.4e-21
553482007102	1 transmembrane helix predicted for SEQ1540 by TMHMM2.0 at aa 34-56
553482007103	hypothetical protein; Provisional; Region: PRK04351
553482007104	Zn-dependent metalloprotease, SprT family [General function prediction only]; Region: SprT; COG3091
553482007105	HMMPfam hit to PF03926, metallopeptidase (SprT family), score 6.8e-65
553482007106	Transcriptional accessory protein [Transcription]; Region: Tex; COG2183
553482007107	Tex-like protein N-terminal domain; Region: Tex_N; pfam09371
553482007108	Likely ribonuclease with RNase H fold; Region: YqgFc; smart00732
553482007109	S1_Tex: The C-terminal S1 domain of a transcription accessory factor called Tex, which has been characterized in Bordetella pertussis and Pseudomonas aeruginosa. The tex gene is essential in Bortella pertusis and is named for its role in toxin expression; Region: S1_Tex; cd05685
553482007110	RNA binding site [nucleotide binding]; other site
553482007111	HMMPfam hit to PF00575, S1 RNA binding domain, score 2.1e-19
553482007112	Predicted helix-turn-helix motif with score 1224.000, SD 3.36 at aa 583-604, sequence VNLEEMAEQLTLGQETLKDIIA
553482007113	PS00283 Soybean trypsin inhibitor (Kunitz) protease inhibitors family signature.
553482007114	Predicted helix-turn-helix motif with score 1623.000, SD 4.71 at aa 4-25, sequence MNHQNISEALGVTPKQISQVLT
553482007115	phosphate transporter ATP-binding protein; Provisional; Region: PRK14240
553482007116	ATP-binding cassette domain of the phosphate transport system; Region: ABC_PstB_phosphate_transporter; cd03260
553482007117	Walker A/P-loop; other site
553482007118	ATP binding site [chemical binding]; other site
553482007119	Q-loop/lid; other site
553482007120	ABC transporter signature motif; other site
553482007121	Walker B; other site
553482007122	D-loop; other site
553482007123	H-loop/switch region; other site
553482007124	HMMPfam hit to PF00005, ABC transporter, score 5.3e-59
553482007125	PS00211 ABC transporters family signature.
553482007126	PS00017 ATP/GTP-binding site motif A (P-loop).
553482007127	phosphate ABC transporter, permease protein PstA; Region: 3a0107s02c; TIGR00974
553482007128	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
553482007129	dimer interface [polypeptide binding]; other site
553482007130	conserved gate region; other site
553482007131	putative PBP binding loops; other site
553482007132	ABC-ATPase subunit interface; other site
553482007133	HMMPfam hit to PF00528, Binding-protein-dependent transport syst, score 1.9e-23
553482007134	6 transmembrane helices predicted for SEQ1545 by TMHMM2.0 at aa 9-30, 60-82, 95-117, 122-144, 176-198 and 241-263
553482007135	PS00402 Binding-protein-dependent transport systems inner membrane comp. sign.
553482007136	ABC-type phosphate transport system, permease component [Inorganic ion transport and metabolism]; Region: PstC; COG0573
553482007137	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
553482007138	dimer interface [polypeptide binding]; other site
553482007139	conserved gate region; other site
553482007140	putative PBP binding loops; other site
553482007141	ABC-ATPase subunit interface; other site
553482007142	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cl00427
553482007143	HMMPfam hit to PF00528, Binding-protein-dependent transport syst, score 2e-11
553482007144	6 transmembrane helices predicted for SEQ1546 by TMHMM2.0 at aa 13-35, 74-96, 109-131, 141-163, 201-223 and 258-280
553482007145	PBP superfamily domain; Region: PBP_like_2; cl17296
553482007146	ABC-type phosphate transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: PstS; COG0226
553482007147	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482007148	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
553482007149	dimer interface [polypeptide binding]; other site
553482007150	phosphorylation site [posttranslational modification]
553482007151	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
553482007152	ATP binding site [chemical binding]; other site
553482007153	Mg2+ binding site [ion binding]; other site
553482007154	G-X-G motif; other site
553482007155	HMMPfam hit to PF02518, Histidine kinase-, DNA gyrase B-, and HSP90, score 4.7e-43
553482007156	HMMPfam hit to PF00512, His Kinase A (phosphoacceptor) domain, score 1.7e-19
553482007157	2 transmembrane helices predicted for SEQ1548 by TMHMM2.0 at aa 7-24 and 29-51
553482007158	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
553482007159	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
553482007160	active site
553482007161	phosphorylation site [posttranslational modification]
553482007162	intermolecular recognition site; other site
553482007163	dimerization interface [polypeptide binding]; other site
553482007164	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
553482007165	DNA binding site [nucleotide binding]
553482007166	HMMPfam hit to PF00486, Transcriptional regulatory protein, C te, score 4.7e-26
553482007167	HMMPfam hit to PF00072, Response regulator receiver domain, score 6.5e-43
553482007168	Predicted permeases [General function prediction only]; Region: COG0701
553482007169	HMMPfam hit to PF03773, Predicted permease, score 9.4e-121
553482007170	7 transmembrane helices predicted for SEQ1551 by TMHMM2.0 at aa 15-37, 58-80, 95-117, 122-144, 211-233, 240-262 and 277-299
553482007171	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482007172	Predicted membrane protein [Function unknown]; Region: COG3689
553482007173	3 transmembrane helices predicted for SEQ1552 by TMHMM2.0 at aa 7-24, 39-61 and 82-104
553482007174	Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase [Carbohydrate transport and metabolism]; Region: BglB; COG2723
553482007175	beta-galactosidase; Region: BGL; TIGR03356
553482007176	HMMPfam hit to PF00232, Glycosyl hydrolase family, score 1.2e-155
553482007177	PS00572 Glycosyl hydrolases family 1 active site.
553482007178	PS00653 Glycosyl hydrolases family 1 N-terminal signature.
553482007179	PTS system, beta-glucoside-specific IIABC component; Region: PTS-II-ABC-beta; TIGR01995
553482007180	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
553482007181	active site turn [active]
553482007182	phosphorylation site [posttranslational modification]
553482007183	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
553482007184	Phosphotransferase system IIA components [Carbohydrate transport and metabolism]; Region: NagE; COG2190
553482007185	HPr interaction site; other site
553482007186	glycerol kinase (GK) interaction site [polypeptide binding]; other site
553482007187	active site
553482007188	phosphorylation site [posttranslational modification]
553482007189	HMMPfam hit to PF00358, phosphoenolpyruvate-dependent sugar phosph, score 1.1e-63
553482007190	PS00371 PTS EIIA domains phosphorylation site signature 1.
553482007191	9 transmembrane helices predicted for SEQ1554 by TMHMM2.0 at aa 106-128, 143-165, 172-194, 204-226, 246-268, 283-305, 352-374, 389-411 and 424-446
553482007192	HMMPfam hit to PF02378, Phosphotransferase system, EIIC, score 4.3e-33
553482007193	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482007194	HMMPfam hit to PF00367, phosphotransferase system, EIIB, score 1.8e-15
553482007195	PS01035 PTS EIIB domains cysteine phosphorylation site signature.
553482007196	transcriptional antiterminator BglG; Provisional; Region: PRK09772
553482007197	CAT RNA binding domain; Region: CAT_RBD; pfam03123
553482007198	PRD domain; Region: PRD; pfam00874
553482007199	PRD domain; Region: PRD; pfam00874
553482007200	HMMPfam hit to PF00874, PRD domain, score 4.7e-15
553482007201	HMMPfam hit to PF00874, PRD domain, score 5.6e-20
553482007202	PS00654 Transcriptional antiterminators bglG family signature.
553482007203	HMMPfam hit to PF03123, CAT RNA binding domain, score 2.3e-29
553482007204	signal recognition particle-docking protein FtsY; Provisional; Region: PRK10416
553482007205	SRP54-type protein, helical bundle domain; Region: SRP54_N; pfam02881
553482007206	The signal recognition particle (SRP) mediates the transport to or across the plasma membrane in bacteria and the endoplasmic reticulum in eukaryotes. SRP recognizes N-terminal sighnal sequences of newly synthesized polypeptides at the ribosome. The...; Region: SRP; cd03115
553482007207	P loop; other site
553482007208	GTP binding site [chemical binding]; other site
553482007209	HMMPfam hit to PF00448, SRP54-type protein, GTPase domain, score 1.1e-112
553482007210	PS00300 SRP54-type proteins GTP-binding domain signature.
553482007211	PS00017 ATP/GTP-binding site motif A (P-loop).
553482007212	HMMPfam hit to PF02881, SRP54-type protein, helical bundle domain, score 5.4e-15
553482007213	haloacid dehalogenase-like hydrolase; Region: Hydrolase_3; pfam08282
553482007214	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
553482007215	HMMPfam hit to PF05116, Sucrose-6F-phosphate phosphohydrolase, score 0.00012
553482007216	HMMPfam hit to PF08282, haloacid dehalogenase-like hydrolase, score 3.6e-80
553482007217	HMMPfam hit to PF00702, haloacid dehalogenase-like hydrolase, score 2.3e-08
553482007218	PS01228 Hypothetical cof family signature 1.
553482007219	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
553482007220	haloacid dehalogenase-like hydrolase; Region: Hydrolase_3; pfam08282
553482007221	active site
553482007222	motif I; other site
553482007223	motif II; other site
553482007224	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
553482007225	HMMPfam hit to PF05116, Sucrose-6F-phosphate phosphohydrolase, score 0.0012
553482007226	HMMPfam hit to PF08282, haloacid dehalogenase-like hydrolase, score 7.6e-71
553482007227	1 transmembrane helix predicted for SEQ1559 by TMHMM2.0 at aa 5-22
553482007228	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
553482007229	putative bacteriocin export ABC transporter, lactococcin 972 group; Region: L_ocin_972_ABC; TIGR03608
553482007230	Walker A/P-loop; other site
553482007231	ATP binding site [chemical binding]; other site
553482007232	Q-loop/lid; other site
553482007233	ABC transporter signature motif; other site
553482007234	Walker B; other site
553482007235	D-loop; other site
553482007236	H-loop/switch region; other site
553482007237	HMMPfam hit to PF00005, ABC transporter, score 1.7e-48
553482007238	PS00017 ATP/GTP-binding site motif A (P-loop).
553482007239	8 transmembrane helices predicted for SEQ1561 by TMHMM2.0 at aa 7-25, 138-160, 189-211, 221-243, 263-282, 559-581, 602-624 and 628-647
553482007240	PS00017 ATP/GTP-binding site motif A (P-loop).
553482007241	Lipase.  Lipases are esterases that can hydrolyze long-chain acyl-triglycerides into di- and monoglycerides, glycerol, and free fatty acids at a water/lipid interface. A typical feature of lipases is "interfacial activation", the process of...; Region: Lipase; cl14883
553482007242	nucleophilic elbow; other site
553482007243	catalytic triad; other site
553482007244	1 transmembrane helix predicted for SEQ1565 by TMHMM2.0 at aa 10-29
553482007245	Chromosome segregation ATPases [Cell division and chromosome partitioning]; Region: Smc; COG1196
553482007246	ATP-binding cassette domain of barmotin, a member of the SMC protein family; Region: ABC_SMC_barmotin; cd03278
553482007247	Walker A/P-loop; other site
553482007248	ATP binding site [chemical binding]; other site
553482007249	Q-loop/lid; other site
553482007250	SMC proteins Flexible Hinge Domain; Region: SMC_hinge; smart00968
553482007251	ATP-binding cassette domain of barmotin, a member of the SMC protein family; Region: ABC_SMC_barmotin; cd03278
553482007252	ABC transporter signature motif; other site
553482007253	Walker B; other site
553482007254	D-loop; other site
553482007255	H-loop/switch region; other site
553482007256	HMMPfam hit to PF02463, RecF/RecN/SMC N terminal domain, score 9.2e-110
553482007257	HMMPfam hit to PF06470, SMC proteins Flexible Hinge Domain, score 3.9e-28
553482007258	PS00017 ATP/GTP-binding site motif A (P-loop).
553482007259	ribonuclease III; Reviewed; Region: rnc; PRK00102
553482007260	RIBOc. Ribonuclease III C terminal domain. This group consists of eukaryotic, bacterial and archeal ribonuclease III (RNAse III) proteins. RNAse III is a double stranded RNA-specific endonuclease. Prokaryotic RNAse III is important in...; Region: RIBOc; cd00593
553482007261	dimerization interface [polypeptide binding]; other site
553482007262	active site
553482007263	metal binding site [ion binding]; metal-binding site
553482007264	Double-stranded RNA binding motif. Binding is not sequence specific but is highly specific for double stranded RNA. Found in a variety of proteins including dsRNA dependent protein kinase PKR, RNA helicases, Drosophila staufen protein, E. coli RNase III; Region: DSRM; cd00048
553482007265	dsRNA binding site [nucleotide binding]; other site
553482007266	HMMPfam hit to PF00035, Double-stranded RNA binding motif, score 2.8e-18
553482007267	HMMPfam hit to PF00636, RNase3 domain, score 9.7e-47
553482007268	PS00517 Ribonuclease III family signature.
553482007269	Transposase [DNA replication, recombination, and repair]; Region: COG5421
553482007270	Transposase [DNA replication, recombination, and repair]; Region: COG5421
553482007271	M protein trans-acting positive regulator (MGA) HTH domain; Region: HTH_Mga; pfam08280
553482007272	Mga helix-turn-helix domain; Region: Mga; pfam05043
553482007273	M protein trans-acting positive regulator (MGA) PRD domain; Region: PRD_Mga; pfam08270
553482007274	PS00038 Myc-type, 'helix-loop-helix' dimerization domain signature.
553482007275	HMMPfam hit to PF08270, M protein trans-acting positive regulator (M, score 5.2e-45
553482007276	HMMPfam hit to PF05043, Mga helix-turn-helix domain, score 1.5e-21
553482007277	HMMPfam hit to PF08280, M protein trans-acting positive regulator (M, score 6.1e-10
553482007278	D12 class N6 adenine-specific DNA methyltransferase; Region: MethyltransfD12; cl17344
553482007279	D12 class N6 adenine-specific DNA methyltransferase; Region: MethyltransfD12; cl17344
553482007280	HMMPfam hit to PF02086, D12 class N6 adenine-specific DNA met, score 1.3e-52
553482007281	PS00018 EF-hand calcium-binding domain.
553482007282	HMMPfam hit to PF02086, D12 class N6 adenine-specific DNA met, score 3e-19
553482007283	PS00092 N-6 Adenine-specific DNA methylases signature.
553482007284	Restriction endonuclease FokI, recognition domain; Region: FokI_N; pfam02981
553482007285	Restriction endonuclease FokI, catalytic domain; Region: FokI_C; pfam02980
553482007286	Restriction endonuclease FokI, C terminal; Region: Endonuc-FokI_C; pfam09254
553482007287	HMMPfam hit to PF02980, Restriction endonuclease FokI, catalytic dom, score 1.2e-32
553482007288	putative transposase OrfB; Reviewed; Region: PHA02517
553482007289	HTH-like domain; Region: HTH_21; pfam13276
553482007290	Integrase core domain; Region: rve; pfam00665
553482007291	Integrase core domain; Region: rve_2; pfam13333
553482007292	HMMPfam hit to PF00665, Integrase core domain, score 1.8e-37
553482007293	CDS contains a frameshift after codon 142. Insertion of additional bases at the frameshift has introduced 11 extra residues. Similar to Streptococcus pyogenes serotype M3 transposase. UniProt:Q1J650 (EMBL:CP000262 (177 aa) fasta scores: E()=2.8e-36, 76.923% id in 182 aa
553482007294	HMMPfam hit to PF02178, no description, score 0.21
553482007295	Predicted helix-turn-helix motif with score 1140.000, SD 3.07 at aa 19-40, sequence KSIKCLSEKFSIAESDLKYMIR
553482007296	Metal-dependent hydrolases of the beta-lactamase superfamily I [General function prediction only]; Region: PhnP; COG1235
553482007297	Predicted Zn-dependent hydrolases of the beta-lactamase fold [General function prediction only]; Region: COG2220
553482007298	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: VicK; COG5002
553482007299	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
553482007300	putative active site [active]
553482007301	heme pocket [chemical binding]; other site
553482007302	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
553482007303	dimer interface [polypeptide binding]; other site
553482007304	phosphorylation site [posttranslational modification]
553482007305	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
553482007306	ATP binding site [chemical binding]; other site
553482007307	Mg2+ binding site [ion binding]; other site
553482007308	G-X-G motif; other site
553482007309	HMMPfam hit to PF02518, Histidine kinase-, DNA gyrase B-, and HSP90, score 3.2e-40
553482007310	HMMPfam hit to PF00512, His Kinase A (phosphoacceptor) domain, score 3.5e-20
553482007311	HMMPfam hit to PF00989, PAS fold, score 9.9e-08
553482007312	1 transmembrane helix predicted for SEQ1576 by TMHMM2.0 at aa 5-27
553482007313	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
553482007314	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
553482007315	active site
553482007316	phosphorylation site [posttranslational modification]
553482007317	intermolecular recognition site; other site
553482007318	dimerization interface [polypeptide binding]; other site
553482007319	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
553482007320	DNA binding site [nucleotide binding]
553482007321	HMMPfam hit to PF00486, Transcriptional regulatory protein, C te, score 1.7e-24
553482007322	HMMPfam hit to PF00072, Response regulator receiver domain, score 1.3e-42
553482007323	Protein of unknown function (DUF3114); Region: DUF3114; pfam11311
553482007324	acyl-CoA synthetase; Validated; Region: PRK07638
553482007325	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
553482007326	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
553482007327	acyl-activating enzyme (AAE) consensus motif; other site
553482007328	acyl-activating enzyme (AAE) consensus motif; other site
553482007329	AMP binding site [chemical binding]; other site
553482007330	active site
553482007331	CoA binding site [chemical binding]; other site
553482007332	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482007333	acetyl-CoA acetyltransferases; Region: AcCoA-C-Actrans; TIGR01930
553482007334	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
553482007335	dimer interface [polypeptide binding]; other site
553482007336	active site
553482007337	HMMPfam hit to PF02803, Thiolase, C-terminal domain, score 3.1e-19
553482007338	1 transmembrane helix predicted for SEQ1580 by TMHMM2.0 at aa 311-333
553482007339	HMMPfam hit to PF00108, Thiolase, N-terminal domain, score 1.2e-15
553482007340	Predicted helix-turn-helix motif with score 1100.000, SD 2.93 at aa 148-169, sequence AGAERVAQAYQMTPSQLNQWTL
553482007341	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
553482007342	Helix-turn-helix domain; Region: HTH_28; pfam13518
553482007343	Predicted helix-turn-helix motif with score 1140.000, SD 3.07 at aa 19-40, sequence KSIKCLSEKFSIAESDLKYMIR
553482007344	HMMPfam hit to PF01527, Transposase, score 0.00062
553482007345	HMMPfam hit to PF02178, no description, score 0.21
553482007346	putative transposase OrfB; Reviewed; Region: PHA02517
553482007347	HTH-like domain; Region: HTH_21; pfam13276
553482007348	Integrase core domain; Region: rve; pfam00665
553482007349	Integrase core domain; Region: rve_2; pfam13333
553482007350	HMMPfam hit to PF00665, Integrase core domain, score 1.1e-37
553482007351	gene remnant. CDS is truncated by the insertion of the downstream IS element and subsequent deletion events. Similar to the N-terminal region of Streptococcus pyogenes lantibiotic transport ATP-binding protein Srtf UniProt:P0C0E2 (EMBL:AB030831 (229 aa) fasta scores: E()=2.6e-06, 44.554% id in 101 aa
553482007352	PS00017 ATP/GTP-binding site motif A (P-loop).
553482007353	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
553482007354	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
553482007355	dimer interface [polypeptide binding]; other site
553482007356	phosphorylation site [posttranslational modification]
553482007357	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
553482007358	ATP binding site [chemical binding]; other site
553482007359	Mg2+ binding site [ion binding]; other site
553482007360	G-X-G motif; other site
553482007361	HMMPfam hit to PF02518, Histidine kinase-, DNA gyrase B-, and HSP90, score 1.5e-14
553482007362	HMMPfam hit to PF00512, His Kinase A (phosphoacceptor) domain, score 1.8e-12
553482007363	2 transmembrane helices predicted for SEQ1586 by TMHMM2.0 at aa 20-42 and 149-171
553482007364	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
553482007365	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
553482007366	active site
553482007367	phosphorylation site [posttranslational modification]
553482007368	intermolecular recognition site; other site
553482007369	dimerization interface [polypeptide binding]; other site
553482007370	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
553482007371	DNA binding site [nucleotide binding]
553482007372	HMMPfam hit to PF00486, Transcriptional regulatory protein, C te, score 3.6e-19
553482007373	HMMPfam hit to PF00072, Response regulator receiver domain, score 1.6e-32
553482007374	Peptidase S8 family domain in Lantiobiotic (lanthionine-containing antibiotics) specific proteases; Region: Peptidases_S8_Lantibiotic_specific_protease; cd07482
553482007375	active site
553482007376	catalytic triad [active]
553482007377	HMMPfam hit to PF00082, Subtilase family, score 5.8e-29
553482007378	PS00138 Serine proteases, subtilase family, serine active site.
553482007379	PS00136 Serine proteases, subtilase family, aspartic acid active site.
553482007380	PS00430 TonB-dependent receptor proteins signature 1.
553482007382	gene remnant. Fragment contains nonsense and frameshift mutations
553482007383	gene remnant. Similar to N-terminal region of Streptococcus suis transposase OrfA UniProt:Q300F6 (EMBL:AAFA02000034 (178 aa) fasta scores: E()=4.4, 39.535% id in 43 aa
553482007384	threonyl-tRNA synthetase; Reviewed; Region: thrS; PRK00413
553482007385	TGS _ThrRS_N:  ThrRS (threonyl-tRNA Synthetase)  is a class II tRNA synthetase that couples threonine to its cognate tRNA.  In addition to its catalytic and anticodon-binding domains, ThrRS has an N-terminal TGS domain, named after the ThrRS, GTPase, and...; Region: TGS_ThrRS_N; cd01667
553482007386	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; smart00863
553482007387	Threonyl-tRNA synthetase (ThrRS) class II core catalytic domain. ThrRS is a homodimer. It is responsible for the attachment of threonine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ThrRS_core; cd00771
553482007388	active site
553482007389	dimer interface [polypeptide binding]; other site
553482007390	motif 1; other site
553482007391	motif 2; other site
553482007392	motif 3; other site
553482007393	ThrRS Threonyl-anticodon binding domain. ThrRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: ThrRS_anticodon; cd00860
553482007394	anticodon binding site; other site
553482007395	HMMPfam hit to PF03129, Anticodon binding domain, score 3e-29
553482007396	HMMPfam hit to PF00587, tRNA synthetase class II core domain (, score 2.6e-55
553482007397	HMMPfam hit to PF07973, Threonyl and Alanyl tRNA synthetase se, score 4.8e-25
553482007398	HMMPfam hit to PF02824, TGS domain, score 1.1e-14
553482007399	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
553482007400	This family is most closely related to the GT1 family of glycosyltransferases. UDP-glucose-diacylglycerol glucosyltransferase (UGDG; also known as 1,2-diacylglycerol 3-glucosyltransferase) catalyzes the transfer of glucose from UDP-glucose to 1; Region: GT1_UGDG_like; cd03817
553482007401	putative ADP-binding pocket [chemical binding]; other site
553482007402	HMMPfam hit to PF00534, Glycosyl transferases group, score 1.7e-25
553482007403	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
553482007404	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
553482007405	HMMPfam hit to PF00534, Glycosyl transferases group, score 3.3e-09
553482007406	cytoplasmic alpha-amylase; Reviewed; Region: PRK09441
553482007407	Alpha amylase catalytic domain found in bacterial and fungal Alpha amylases (also called 1,4-alpha-D-glucan-4-glucanohydrolase); Region: AmyAc_bac_fung_AmyA; cd11318
553482007408	active site
553482007409	Na/Ca binding site [ion binding]; other site
553482007410	catalytic site [active]
553482007411	Domain of unknown function (DUF1939); Region: DUF1939; pfam09154
553482007412	HMMPfam hit to PF00128, Alpha amylase, catalytic domain, score 3.8e-69
553482007413	catabolite control protein A; Region: ccpA; TIGR01481
553482007414	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
553482007415	DNA binding site [nucleotide binding]
553482007416	domain linker motif; other site
553482007417	Ligand-binding domain of the catabolite control protein A (CcpA), which functions as the major transcriptional regulator of carbon catabolite repression/regulation; Region: PBP1_CcpA_like; cd06298
553482007418	dimerization interface [polypeptide binding]; other site
553482007419	effector binding site; other site
553482007420	HMMPfam hit to PF00532, Periplasmic binding proteins and sugar b, score 6.6e-07
553482007421	HMMPfam hit to PF00356, Bacterial regulatory proteins, lacI fami, score 5.4e-13
553482007422	Predicted helix-turn-helix motif with score 2166.000, SD 6.56 at aa 7-28, sequence ITIYDVAREAGVSMATVSRVVN
553482007423	PS00356 Bacterial regulatory proteins, lacI family signature.
553482007424	Xaa-Pro aminopeptidase [Amino acid transport and metabolism]; Region: PepP; COG0006
553482007425	Creatinase/Prolidase N-terminal domain; Region: Creatinase_N; pfam01321
553482007426	Similar to Prolidase and Aminopeptidase P. The members of this subfamily presumably catalyse hydrolysis of Xaa-Pro dipeptides and/or release of any N-terminal amino acid, including proline, that is linked with proline; Region: APP-like; cd01092
553482007427	active site
553482007428	HMMPfam hit to PF00557, metallopeptidase family M24, score 1.6e-74
553482007429	PS00491 Aminopeptidase P and proline dipeptidase signature.
553482007430	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
553482007431	ATP-binding cassette domain of multidrug resistance protein-like transporters; Region: ABCC_MRP_Like; cd03228
553482007432	Walker A/P-loop; other site
553482007433	ATP binding site [chemical binding]; other site
553482007434	Q-loop/lid; other site
553482007435	ABC transporter signature motif; other site
553482007436	Walker B; other site
553482007437	D-loop; other site
553482007438	H-loop/switch region; other site
553482007439	HMMPfam hit to PF00005, ABC transporter, score 5.8e-36
553482007440	PS00211 ABC transporters family signature.
553482007441	PS00017 ATP/GTP-binding site motif A (P-loop).
553482007442	5 transmembrane helices predicted for SEQ1598 by TMHMM2.0 at aa 13-35, 50-72, 120-142, 147-169 and 230-252
553482007443	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
553482007444	non-specific DNA binding site [nucleotide binding]; other site
553482007445	salt bridge; other site
553482007446	sequence-specific DNA binding site [nucleotide binding]; other site
553482007447	transcriptional activator, Rgg/GadR/MutR family, C-terminal domain; Region: RGG_Cterm; TIGR01716
553482007448	HMMPfam hit to PF01381, Helix-turn-helix, score 4.5e-08
553482007449	NAD(P)H:FMN oxidoreductase family. This domain catalyzes the reduction of flavin, nitrocompound, quinones and azo compounds using NADH or NADPH as an electron donor. The enzyme is a homodimer, and each monomer binds a FMN as co-factor. This family...; Region: NfsB_like_nitroreductase; cd02149
553482007450	dimer interface [polypeptide binding]; other site
553482007451	FMN binding site [chemical binding]; other site
553482007452	HMMPfam hit to PF00881, Nitroreductase family, score 1.6e-47
553482007453	undecaprenyl phosphate 4-deoxy-4-formamido-L-arabinose transferase; Provisional; Region: PRK10714
553482007454	Bacterial DPM1_like enzymes are related to eukaryotic DPM1; Region: DPM1_like_bac; cd04187
553482007455	Ligand binding site; other site
553482007456	Putative Catalytic site; other site
553482007457	DXD motif; other site
553482007458	HMMPfam hit to PF00535, Glycosyl transferase family, score 1.9e-31
553482007459	2 transmembrane helices predicted for SEQ1601 by TMHMM2.0 at aa 230-252 and 264-286
553482007460	Small protein B (SmpB) is a component of the trans-translation system in prokaryotes for releasing stalled ribosome from damaged messenger RNAs; Region: SmpB; cd09294
553482007461	SmpB-tmRNA interface; other site
553482007462	HMMPfam hit to PF01668, SmpB protein, score 2.1e-36
553482007463	PS01317 Protein smpB signature.
553482007464	ribonuclease R; Region: RNase_R; TIGR02063
553482007465	Ribonuclease B OB domain; Region: OB_RNB; pfam08206
553482007466	RNB domain; Region: RNB; pfam00773
553482007467	S1_RNase_R: RNase R C-terminal S1 domain. RNase R is a processive 3' to 5' exoribonuclease, which is a homolog of RNase II. RNase R degrades RNA with secondary structure having a 3' overhang of at least 7 nucleotides. RNase R and PNPase...; Region: S1_RNase_R; cd04471
553482007468	RNA binding site [nucleotide binding]; other site
553482007469	HMMPfam hit to PF00575, S1 RNA binding domain, score 1.7e-12
553482007470	PS01175 Ribonuclease II family signature.
553482007471	HMMPfam hit to PF00773, RNB-like protein, score 2.3e-97
553482007472	HMMPfam hit to PF08206, Ribonuclease B OB domain, score 2.5e-20
553482007473	preprotein translocase subunit SecG; Reviewed; Region: secG; PRK06870
553482007474	HMMPfam hit to PF03840, Preprotein translocase SecG subunit, score 1.8e-30
553482007475	2 transmembrane helices predicted for SEQ1604 by TMHMM2.0 at aa 5-22 and 53-75
553482007476	50S ribosomal protein L33; Validated; Region: rpmG; PRK00595
553482007477	Fibronectin-binding protein signal sequence; Region: Fb_signal; pfam08341
553482007478	TQXA domain; Region: TQXA_dom; TIGR03934
553482007479	2 transmembrane helices predicted for SEQ1606 by TMHMM2.0 at aa 9-31 and 603-622
553482007480	HMMPfam hit to PF01391, Collagen triple helix repeat (20 copies), score 1.1e-13
553482007481	HMMPfam hit to PF01391, Collagen triple helix repeat (20 copies), score 2.5e-09
553482007482	HMMPfam hit to PF01391, Collagen triple helix repeat (20 copies), score 2.8e-14
553482007483	HMMPfam hit to PF01391, Collagen triple helix repeat (20 copies), score 4.9e-15
553482007484	CDS contains a nonsense mutation (ochre) after codon 214
553482007485	1 transmembrane helix predicted for SEQ1607 by TMHMM2.0 at aa 9-31
553482007486	HMMPfam hit to PF08341, Fibronectin-binding protein signal sequence, score 1.7e-14
553482007487	1 transmembrane helix predicted for SEQ1608 by TMHMM2.0 at aa 72-91
553482007488	Dephospho-CoA kinase [Coenzyme metabolism]; Region: CoaE; COG0237
553482007489	Dephospho-coenzyme A kinase (DPCK, EC 2.7.1.24) catalyzes the phosphorylation of dephosphocoenzyme A (dCoA) to yield CoA, which is the final step in CoA biosynthesis; Region: DPCK; cd02022
553482007490	CoA-binding site [chemical binding]; other site
553482007491	ATP-binding [chemical binding]; other site
553482007492	HMMPfam hit to PF01121, Dephospho-CoA kinase, score 7.7e-49
553482007493	PS00017 ATP/GTP-binding site motif A (P-loop).
553482007494	formamidopyrimidine/5-formyluracil/ 5-hydroxymethyluracil DNA glycosylase; Validated; Region: PRK01103
553482007495	N-terminal domain of Escherichia coli Fpg1/MutM and related bacterial DNA glycosylases; Region: EcFpg-like_N; cd08966
553482007496	DNA binding site [nucleotide binding]
553482007497	catalytic residue [active]
553482007498	H2TH interface [polypeptide binding]; other site
553482007499	putative catalytic residues [active]
553482007500	turnover-facilitating residue; other site
553482007501	intercalation triad [nucleotide binding]; other site
553482007502	8OG recognition residue [nucleotide binding]; other site
553482007503	putative reading head residues; other site
553482007504	Formamidopyrimidine-DNA glycosylase H2TH domain; Region: H2TH; pfam06831
553482007505	Zinc finger found in FPG and IleRS; Region: zf-FPG_IleRS; pfam06827
553482007506	HMMPfam hit to PF06827, Zinc finger found in FPG and IleRS, score 2e-10
553482007507	HMMPfam hit to PF06831, Formamidopyrimidine-DNA glycosylase H2, score 1.9e-42
553482007508	HMMPfam hit to PF01149, Formamidopyrimidine-DNA glycosylase N-, score 8.3e-51
553482007509	Glycosyl hydrolases family 35; Region: Glyco_hydro_35; pfam01301
553482007510	HMMPfam hit to PF01301, Glycosyl hydrolases family, score 6.4e-175
553482007511	HMMPfam hit to PF02449, Beta-galactosidase, score 0.00029
553482007512	YSIRK type signal peptide; Region: YSIRK_signal; cl04650
553482007513	choice-of-anchor C domain; Region: choice_anch_C; TIGR04362
553482007514	Laminarinase, member of the glycosyl hydrolase family 16; Region: GH16_laminarinase_like; cd08023
553482007515	active site
553482007516	catalytic residues [active]
553482007517	Pentraxins are plasma proteins characterized by their pentameric discoid assembly and their Ca2+ dependent ligand binding, such as Serum amyloid P component (SAP) and C-reactive Protein (CRP), which are cytokine-inducible acute-phase proteins implicated...; Region: PTX; cl00102
553482007518	Sialidases or neuraminidases function to bind and hydrolyze terminal sialic acid residues from various glycoconjugates as well as playing roles in pathogenesis, bacterial nutrition and cellular interactions. They have a six-bladed, beta-propeller fold...; Region: Sialidase; cd00260
553482007519	Sialidases or neuraminidases function to bind and hydrolyze terminal sialic acid residues from various glycoconjugates as well as playing roles in pathogenesis, bacterial nutrition and cellular interactions. They have a six-bladed, beta-propeller fold...; Region: Sialidase; cd00260
553482007520	Asp-box motif; other site
553482007521	catalytic site [active]
553482007522	HMMPfam hit to PF02012, BNR/Asp-box repeat, score 1.4
553482007523	HMMPfam hit to PF02012, BNR/Asp-box repeat, score 0.038
553482007524	HMMPfam hit to PF02012, BNR/Asp-box repeat, score 0.51
553482007525	HMMPfam hit to PF02012, BNR/Asp-box repeat, score 0.085
553482007526	HMMPfam hit to PF00722, Glycosyl hydrolases family, score 1.4e-19
553482007527	HMMPfam hit to PF02018, Carbohydrate binding domain, score 0.00028
553482007528	1 transmembrane helix predicted for SEQ1612 by TMHMM2.0 at aa 20-42
553482007529	PS00099 Thiolases active site.
553482007530	HMMPfam hit to PF04650, YSIRK type signal peptide, score 2.9e-06
553482007531	CDS contains a frameshift around codon 313. Similar to Listeria monocytogenes PTS system, cellobiose-specific, IIC component UniProt:Q4ETL0 (EMBL:AADQ01000007 (454 aa) fasta scores: E()=2.5e-72, 47.556% id in 450 aa
553482007532	2 transmembrane helices predicted for SEQ1613 by TMHMM2.0 at aa 43-65 and 95-114
553482007533	HMMPfam hit to PF02378, Phosphotransferase system, EIIC, score 3.5e-20
553482007534	6 transmembrane helices predicted for SEQ1614 by TMHMM2.0 at aa 31-53, 73-95, 107-129, 173-192, 212-231 and 254-276
553482007535	Phosphotransferase system cellobiose-specific component IIC [Carbohydrate transport and metabolism]; Region: CelB; COG1455
553482007536	cellobiose phosphotransferase system IIC component; Reviewed; Region: celD; PRK09592
553482007537	10 transmembrane helices predicted for SEQ1615 by TMHMM2.0 at aa 34-56, 76-93, 100-122, 137-159, 180-202, 217-239, 241-263, 293-312, 350-372 and 402-424
553482007538	HMMPfam hit to PF02378, Phosphotransferase system, EIIC, score 4.2e-73
553482007539	PTS_IIA, PTS system, lactose/cellobiose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_lac; cd00215
553482007540	active site
553482007541	methionine cluster; other site
553482007542	phosphorylation site [posttranslational modification]
553482007543	metal binding site [ion binding]; metal-binding site
553482007544	HMMPfam hit to PF02255, PTS system, Lactose/Cellobiose specific IIA, score 1.6e-39
553482007545	PTS_IIB_chitobiose_lichenan: subunit IIB of enzyme II (EII) of the N,N-diacetylchitobiose-specific and lichenan-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In these systems, EII is either a lichenan- or an N; Region: PTS_IIB_chitobiose_lichenan; cd05564
553482007546	active site
553482007547	P-loop; other site
553482007548	phosphorylation site [posttranslational modification]
553482007549	HMMPfam hit to PF02302, PTS system, Lactose/Cellobiose specific IIB, score 4.2e-33
553482007550	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
553482007551	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
553482007552	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
553482007553	Predicted helix-turn-helix motif with score 1378.000, SD 3.88 at aa 23-44, sequence ISRIDISKLTHITPATVGAITK
553482007554	HMMPfam hit to PF00480, ROK family, score 5e-09
553482007555	Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly...; Region: Nudix_Hydrolase_18; cd04677
553482007556	nudix motif; other site
553482007557	HMMPfam hit to PF00293, NUDIX domain, score 3.5e-19
553482007558	PS00893 mutT domain signature.
553482007559	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
553482007560	Helix-turn-helix domain; Region: HTH_28; pfam13518
553482007561	Predicted helix-turn-helix motif with score 1140.000, SD 3.07 at aa 19-40, sequence KSIKCLSEKFSIAESDLKYMIR
553482007562	HMMPfam hit to PF01527, Transposase, score 0.00062
553482007563	HMMPfam hit to PF02178, no description, score 0.21
553482007564	putative transposase OrfB; Reviewed; Region: PHA02517
553482007565	HTH-like domain; Region: HTH_21; pfam13276
553482007566	Integrase core domain; Region: rve; pfam00665
553482007567	Integrase core domain; Region: rve_2; pfam13333
553482007568	HMMPfam hit to PF00665, Integrase core domain, score 1.1e-37
553482007569	H+/gluconate symporter and related permeases [Carbohydrate transport and metabolism / Amino acid transport and metabolism]; Region: GntT; COG2610
553482007570	fructuronate transporter; Provisional; Region: PRK10034; cl15264
553482007571	HMMPfam hit to PF02447, GntP family permease, score 7.4e-05
553482007572	12 transmembrane helices predicted for SEQ1623 by TMHMM2.0 at aa 4-21, 28-50, 65-87, 108-130, 150-172, 185-207, 239-261, 268-285, 307-329, 342-364, 387-409 and 422-441
553482007573	HMMPfam hit to PF03600, Citrate transporter, score 1.7e-37
553482007574	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482007575	3-hydroxybutyrate dehydrogenase; Provisional; Region: PRK12429
553482007576	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
553482007577	NAD(P) binding site [chemical binding]; other site
553482007578	active site
553482007579	HMMPfam hit to PF00106, short chain dehydrogenase, score 5e-21
553482007580	PS00061 Short-chain dehydrogenases/reductases family signature.
553482007581	3-oxoacid CoA-transferase, B subunit; Region: pcaJ_scoB_fam; TIGR02428
553482007582	HMMPfam hit to PF01144, Coenzyme A transferase, score 4.1e-48
553482007583	PS01274 CoA transferases signature 2.
553482007584	Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit [Lipid metabolism]; Region: AtoD; COG1788
553482007585	HMMPfam hit to PF01144, Coenzyme A transferase, score 1e-77
553482007586	PS01273 CoA transferases signature 1.
553482007587	putative acyltransferase; Provisional; Region: PRK05790
553482007588	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
553482007589	dimer interface [polypeptide binding]; other site
553482007590	active site
553482007591	HMMPfam hit to PF02803, Thiolase, C-terminal domain, score 4e-70
553482007592	PS00099 Thiolases active site.
553482007593	PS00737 Thiolases signature 2.
553482007594	HMMPfam hit to PF00108, Thiolase, N-terminal domain, score 9.8e-154
553482007595	DNA-binding transcriptional regulator HcaR; Provisional; Region: PRK09906
553482007596	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
553482007597	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
553482007598	dimerization interface [polypeptide binding]; other site
553482007599	HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 4.1e-09
553482007600	Predicted helix-turn-helix motif with score 1789.000, SD 5.28 at aa 17-38, sequence FNLSRTAQQLYISQPTLSIMIN
553482007601	HMMPfam hit to PF03466, LysR substrate binding domain, score 5.8e-12
553482007602	6 transmembrane helices predicted for SEQ1629 by TMHMM2.0 at aa 17-39, 154-176, 208-230, 265-287, 294-316 and 353-375
553482007603	PS00225 Crystallins beta and gamma 'Greek key' motif signature.
553482007604	ABC-type Na+ transport system, ATPase component [Energy production and conversion / Inorganic ion transport and metabolism]; Region: NatA; COG4555
553482007605	ABC-type multidrug transport system, ATPase component; Region: ABC_drug_resistance_like; cd03264
553482007606	Walker A/P-loop; other site
553482007607	ATP binding site [chemical binding]; other site
553482007608	Q-loop/lid; other site
553482007609	ABC transporter signature motif; other site
553482007610	Walker B; other site
553482007611	D-loop; other site
553482007612	H-loop/switch region; other site
553482007613	HMMPfam hit to PF00005, ABC transporter, score 4.1e-52
553482007614	PS00211 ABC transporters family signature.
553482007615	PS00017 ATP/GTP-binding site motif A (P-loop).
553482007616	LytTr DNA-binding domain; Region: LytTR; cl04498
553482007617	gene remnant. Similar to the C-terminal region of Streptococcus pyogenes serotype M6 hypothetical protein UniProt:Q5XDG1 (EMBL:CP000003 (84 aa) fasta scores: E()=3.8e-11, 66.667% id in 48 aa
553482007618	GTPase Era; Reviewed; Region: era; PRK00089
553482007619	E. coli Ras-like protein (Era) is a multifunctional GTPase; Region: Era; cd04163
553482007620	G1 box; other site
553482007621	GTP/Mg2+ binding site [chemical binding]; other site
553482007622	Switch I region; other site
553482007623	G2 box; other site
553482007624	Switch II region; other site
553482007625	G3 box; other site
553482007626	G4 box; other site
553482007627	G5 box; other site
553482007628	KH domain; Region: KH_2; pfam07650
553482007629	HMMPfam hit to PF07650, KH domain, score 7.1e-29
553482007630	HMMPfam hit to PF01926, GTPase of unknown function, score 6.3e-40
553482007631	PS00017 ATP/GTP-binding site motif A (P-loop).
553482007632	Diacylglycerol kinase [Cell envelope biogenesis, outer membrane]; Region: DgkA; COG0818
553482007633	2 transmembrane helices predicted for SEQ1634 by TMHMM2.0 at aa 41-63 and 103-125
553482007634	HMMPfam hit to PF01219, Prokaryotic diacylglycerol kinase, score 3.2e-48
553482007635	PS01069 Prokaryotic diacylglycerol kinase signature.
553482007636	metal-binding heat shock protein; Provisional; Region: PRK00016
553482007637	HMMPfam hit to PF02130, Uncharacterized protein family UPF0054, score 8.4e-26
553482007638	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
553482007639	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
553482007640	Coenzyme A binding pocket [chemical binding]; other site
553482007641	HMMPfam hit to PF00583, Acetyltransferase (GNAT) family, score 1.9e-07
553482007642	Uncharacterized subfamily of Uracil-DNA glycosylases; Region: UDG_like_1; cd10033
553482007643	putative uracil binding site [chemical binding]; other site
553482007644	putative active site [active]
553482007645	Phosphate starvation-inducible protein PhoH, predicted ATPase [Signal transduction mechanisms]; Region: PhoH; COG1702
553482007646	PhoH-like protein; Region: PhoH; pfam02562
553482007647	HMMPfam hit to PF02562, PhoH-like protein, score 1.6e-136
553482007648	PS00017 ATP/GTP-binding site motif A (P-loop).
553482007649	hypothetical protein; Provisional; Region: PRK13672
553482007650	HMMPfam hit to PF06855, Protein of unknown function (DUF1250), score 1.1e-27
553482007651	methionine sulfoxide reductase A; Provisional; Region: PRK14054
553482007652	HMMPfam hit to PF01625, Peptide methionine sulfoxide reductase, score 2.5e-80
553482007653	Predicted RNA-bindining protein (contains S1 and HTH domains) [General function prediction only]; Region: COG2996
553482007654	S1 domain; Region: S1_2; pfam13509
553482007655	Ribosomal protein S1-like RNA-binding domain; Region: S1; smart00316
553482007656	ribosome recycling factor; Reviewed; Region: frr; PRK00083
553482007657	Ribosome recycling factor (RRF). Ribosome recycling factor dissociates the posttermination complex, composed of the ribosome, deacylated tRNA, and mRNA, after termination of translation.  Thus ribosomes are "recycled" and ready for another...; Region: RRF; cd00520
553482007658	hinge region; other site
553482007659	HMMPfam hit to PF01765, Ribosome recycling factor, score 9.6e-94
553482007660	UMP kinase (UMPK)-Ec, the microbial/chloroplast uridine monophosphate kinase (uridylate kinase) enzyme that catalyzes UMP phosphorylation and plays a key role in pyrimidine nucleotide biosynthesis; regulation of this process is via feed-back control and...; Region: AAK_UMPK-PyrH-Ec; cd04254
553482007661	putative nucleotide binding site [chemical binding]; other site
553482007662	uridine monophosphate binding site [chemical binding]; other site
553482007663	homohexameric interface [polypeptide binding]; other site
553482007664	HMMPfam hit to PF00696, Amino acid kinase family, score 3.6e-59
553482007665	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
553482007666	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
553482007667	Walker A/P-loop; other site
553482007668	ATP binding site [chemical binding]; other site
553482007669	Q-loop/lid; other site
553482007670	ABC transporter signature motif; other site
553482007671	Walker B; other site
553482007672	D-loop; other site
553482007673	H-loop/switch region; other site
553482007674	HMMPfam hit to PF00005, ABC transporter, score 2.3e-53
553482007675	PS00211 ABC transporters family signature.
553482007676	PS00017 ATP/GTP-binding site motif A (P-loop).
553482007677	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
553482007678	nickel import ATP-binding protein NikD; Region: nickel_nikD; TIGR02770
553482007679	Walker A/P-loop; other site
553482007680	ATP binding site [chemical binding]; other site
553482007681	Q-loop/lid; other site
553482007682	ABC transporter signature motif; other site
553482007683	Walker B; other site
553482007684	D-loop; other site
553482007685	H-loop/switch region; other site
553482007686	HMMPfam hit to PF00005, ABC transporter, score 2.5e-38
553482007687	PS00211 ABC transporters family signature.
553482007688	PS00017 ATP/GTP-binding site motif A (P-loop).
553482007689	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
553482007690	nickel ABC transporter, permease subunit NikC; Region: nickel_nikC; TIGR02790
553482007691	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
553482007692	dimer interface [polypeptide binding]; other site
553482007693	conserved gate region; other site
553482007694	putative PBP binding loops; other site
553482007695	ABC-ATPase subunit interface; other site
553482007696	HMMPfam hit to PF00528, Binding-protein-dependent transport syst, score 2.1e-28
553482007697	6 transmembrane helices predicted for SEQ1646 by TMHMM2.0 at aa 5-27, 70-92, 99-118, 122-144, 189-211 and 231-253
553482007698	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
553482007699	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
553482007700	dimer interface [polypeptide binding]; other site
553482007701	conserved gate region; other site
553482007702	putative PBP binding loops; other site
553482007703	ABC-ATPase subunit interface; other site
553482007704	HMMPfam hit to PF00528, Binding-protein-dependent transport syst, score 5.5e-43
553482007705	6 transmembrane helices predicted for SEQ1647 by TMHMM2.0 at aa 5-27, 94-116, 129-151, 166-183, 225-247 and 267-289
553482007706	ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747
553482007707	The substrate-binding component of an ABC-type nickel import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA; cd08489
553482007708	substrate binding site [chemical binding]; other site
553482007709	HMMPfam hit to PF00496, Bacterial extracellular solute-binding prot, score 6.4e-81
553482007710	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482007711	Fibronectin-binding protein signal sequence; Region: Fb_signal; pfam08341
553482007712	TQXA domain; Region: TQXA_dom; TIGR03934
553482007713	HMMPfam hit to PF08341, Fibronectin-binding protein signal sequence, score 1.1e-06
553482007714	HMMPfam hit to PF01391, Collagen triple helix repeat (20 copies), score 3.3e-15
553482007715	HMMPfam hit to PF01391, Collagen triple helix repeat (20 copies), score 3.8e-07
553482007716	1 transmembrane helix predicted for SEQ1649 by TMHMM2.0 at aa 491-510
553482007717	Ribosomal protein L1.  The L1 protein, located near the E-site of the ribosome, forms part of the L1 stalk along with 23S rRNA.  In bacteria and archaea, L1 functions both as a ribosomal protein that binds rRNA, and as a translation repressor that binds...; Region: Ribosomal_L1; cd00403
553482007718	mRNA/rRNA interface [nucleotide binding]; other site
553482007719	HMMPfam hit to PF00687, Ribosomal protein L1p/L10e family, score 4.7e-117
553482007720	50S ribosomal protein L11; Validated; Region: rplK; PRK00140
553482007721	Ribosomal protein L11. Ribosomal protein L11, together with proteins L10 and L7/L12, and 23S rRNA, form the L7/L12 stalk on the surface of the large subunit of the ribosome. The homologous eukaryotic cytoplasmic protein is also called 60S ribosomal...; Region: Ribosomal_L11; cd00349
553482007722	23S rRNA interface [nucleotide binding]; other site
553482007723	L7/L12 interface [polypeptide binding]; other site
553482007724	putative thiostrepton binding site; other site
553482007725	L25 interface [polypeptide binding]; other site
553482007726	PS00359 Ribosomal protein L11 signature.
553482007727	HMMPfam hit to PF00298, Ribosomal protein L11, RNA binding do, score 4.1e-41
553482007728	HMMPfam hit to PF03946, Ribosomal protein L11, N-terminal dom, score 5.1e-35
553482007729	Transcriptional regulators [Transcription]; Region: PurR; COG1609
553482007730	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
553482007731	DNA binding site [nucleotide binding]
553482007732	domain linker motif; other site
553482007733	HMMPfam hit to PF00356, Bacterial regulatory proteins, lacI family, score 8.9e-13
553482007734	Predicted helix-turn-helix motif with score 2253.000, SD 6.86 at aa 5-26, sequence VTIKDVAREAGVSVATVSYVIN
553482007735	PS00356 Bacterial regulatory proteins, lacI family signature.
553482007736	Protein of unknown function (DUF3397); Region: DUF3397; pfam11877
553482007737	3 transmembrane helices predicted for SEQ1653 by TMHMM2.0 at aa 7-29, 58-80 and 93-115
553482007738	DNA segregation ATPase FtsK/SpoIIIE and related proteins [Cell division and chromosome partitioning]; Region: FtsK; COG1674
553482007739	FtsK/SpoIIIE family; Region: FtsK_SpoIIIE; pfam01580
553482007740	Ftsk gamma domain; Region: Ftsk_gamma; pfam09397
553482007741	HMMPfam hit to PF01580, FtsK/SpoIIIE family, score 5.4e-76
553482007742	PS00017 ATP/GTP-binding site motif A (P-loop).
553482007743	5 transmembrane helices predicted for SEQ1655 by TMHMM2.0 at aa 49-68, 78-100, 107-129, 144-166 and 173-195
553482007744	Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family [Posttranslational modification, protein turnover, chaperones]; Region: PpiB; COG0652
553482007745	active site
553482007746	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482007747	HMMPfam hit to PF00160, Cyclophilin type peptidyl-prolyl cis-tr, score 3e-43
553482007748	ABC-type Mn2+/Zn2+ transport systems, permease components [Inorganic ion transport and metabolism]; Region: ZnuB; COG1108
553482007749	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
553482007750	ABC-ATPase subunit  interface; other site
553482007751	dimer interface [polypeptide binding]; other site
553482007752	putative PBP binding regions; other site
553482007753	7 transmembrane helices predicted for SEQ1658 by TMHMM2.0 at aa 15-37, 58-80, 95-117, 137-159, 179-201, 214-236 and 246-268
553482007754	HMMPfam hit to PF00950, ABC 3 transport family, score 1.2e-127
553482007755	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482007756	ABC-type Mn/Zn transport systems, ATPase component [Inorganic ion transport and metabolism]; Region: ZnuC; COG1121
553482007757	ATP-binding cassette domain of the metal-type transporters; Region: ABC_Metallic_Cations; cd03235
553482007758	HMMPfam hit to PF00005, ABC transporter, score 8.1e-51
553482007759	PS00211 ABC transporters family signature.
553482007760	PS00017 ATP/GTP-binding site motif A (P-loop).
553482007761	ABC-type metal ion transport system, periplasmic component/surface adhesin [Inorganic ion transport and metabolism]; Region: LraI; COG0803
553482007762	Metal binding protein PsaA.  These proteins have been shown to function as initial receptors in ABC transport of Mn2+ and as surface adhesins in some eubacterial species.  They belong to the TroA superfamily of periplasmic metal binding proteins that...; Region: PsaA; cd01137
553482007763	metal binding site [ion binding]; metal-binding site
553482007764	HMMPfam hit to PF01297, Periplasmic solute binding protein family, score 1.3e-142
553482007765	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482007766	Mn-dependent transcriptional regulator [Transcription]; Region: TroR; COG1321
553482007767	Iron dependent repressor, N-terminal DNA binding domain; Region: Fe_dep_repress; pfam01325
553482007768	Iron dependent repressor, metal binding and dimerisation domain; Region: Fe_dep_repr_C; pfam02742
553482007769	FeoA domain; Region: FeoA; pfam04023
553482007770	HMMPfam hit to PF01047, MarR family, score 0.0002
553482007771	HMMPfam hit to PF01325, Iron dependent repressor, N-terminal D, score 1.5e-11
553482007772	Predicted helix-turn-helix motif with score 1322.000, SD 3.69 at aa 22-43, sequence ISNKMVAERMKVSAPAVSEMIK
553482007773	HMMPfam hit to PF02742, Iron dependent repressor, metal bindin, score 8e-23
553482007774	HMMPfam hit to PF04023, FeoA domain, score 1.1e-12
553482007775	5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Validated; Region: PRK05584
553482007776	5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Region: MTA/SAH-Nsdase; TIGR01704
553482007777	HMMPfam hit to PF01048, Phosphorylase family, score 1.2e-65
553482007778	1 transmembrane helix predicted for SEQ1663 by TMHMM2.0 at aa 61-80
553482007779	PS00038 Myc-type, 'helix-loop-helix' dimerization domain signature.
553482007780	ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+; Region: ADPRase_NUDT5; cd03424
553482007781	dimer interface [polypeptide binding]; other site
553482007782	ADP-ribose binding site [chemical binding]; other site
553482007783	active site
553482007784	nudix motif; other site
553482007785	metal binding site [ion binding]; metal-binding site
553482007786	HMMPfam hit to PF00293, NUDIX domain, score 4.5e-20
553482007787	bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase; Provisional; Region: glmU; PRK14354
553482007788	N-terminal domain of bacterial GlmU; Region: GT2_GlmU_N_bac; cd02540
553482007789	Substrate binding site; other site
553482007790	Mg++ binding site; other site
553482007791	N-acetyl-glucosamine-1-phosphate uridyltransferase (GlmU), C-terminal left-handed beta-helix (LbH) acetyltransferase domain: GlmU is also known as UDP-N-acetylglucosamine pyrophosphorylase. It is a bifunctional bacterial enzyme that catalyzes two...; Region: LbH_GlmU_C; cd03353
553482007792	active site
553482007793	substrate binding site [chemical binding]; other site
553482007794	CoA binding site [chemical binding]; other site
553482007795	HMMPfam hit to PF00132, Bacterial transferase hexapeptide (th, score 14
553482007796	HMMPfam hit to PF00132, Bacterial transferase hexapeptide (th, score 1.2
553482007797	HMMPfam hit to PF00132, Bacterial transferase hexapeptide (th, score 36
553482007798	HMMPfam hit to PF00132, Bacterial transferase hexapeptide (th, score 42
553482007799	HMMPfam hit to PF00132, Bacterial transferase hexapeptide (th, score 0.99
553482007800	HMMPfam hit to PF00132, Bacterial transferase hexapeptide (th, score 9.8
553482007801	HMMPfam hit to PF00132, Bacterial transferase hexapeptide (th, score 4.2
553482007802	HMMPfam hit to PF00483, Nucleotidyl transferase, score 1.6e-10
553482007803	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
553482007804	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
553482007805	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
553482007806	HMMPfam hit to PF02894, Oxidoreductase family, C-terminal alph, score 0.21
553482007807	HMMPfam hit to PF01408, Oxidoreductase family, NAD-binding Ros, score 7.5e-34
553482007808	HMMPfam hit to PF01118, Semialdehyde dehydrogenase, NAD bindin, score 1.4e-09
553482007809	CDS contains a nonsense mutation (opal) after codon 50. Similar to Streptococcus agalactiae hypothetical protein UniProt:Q3CZK4 (EMBL:AAJS01000069 (150 aa) fasta scores: E()=3.7e-37, 68.493% id in 146 aa
553482007810	HMMPfam hit to PF06171, Protein of unknown function (DUF984), score 1.1e-62
553482007811	3-ketoacyl-(acyl-carrier-protein) reductase; Provisional; Region: fabG; PRK06550
553482007812	classical (c) SDRs; Region: SDR_c; cd05233
553482007813	NAD(P) binding site [chemical binding]; other site
553482007814	active site
553482007815	HMMPfam hit to PF00106, short chain dehydrogenase, score 9e-20
553482007816	PS00061 Short-chain dehydrogenases/reductases family signature.
553482007817	Protein of unknown function (DUF2829); Region: DUF2829; pfam11195
553482007818	CDS contains a frameshift after codon 33. CDS is intact in Streptococcus zooepidemicus
553482007819	HMMPfam hit to PF03734, ErfK/YbiS/YcfS/YnhG, score 7.4e-13
553482007820	valyl-tRNA synthetase; Reviewed; Region: valS; PRK05729
553482007821	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
553482007822	active site
553482007823	HIGH motif; other site
553482007824	nucleotide binding site [chemical binding]; other site
553482007825	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
553482007826	catalytic core domain of valyl-tRNA synthetases; Region: ValRS_core; cd00817
553482007827	active site
553482007828	KMSKS motif; other site
553482007829	Anticodon-binding domain of valyl tRNA synthetases; Region: Anticodon_Ia_Val; cd07962
553482007830	tRNA binding surface [nucleotide binding]; other site
553482007831	anticodon binding site; other site
553482007832	Valyl tRNA synthetase tRNA binding arm; Region: Val_tRNA-synt_C; pfam10458
553482007833	HMMPfam hit to PF08264, Anticodon-binding domain, score 2.7e-60
553482007834	HMMPfam hit to PF00133, tRNA synthetases class I (I, L, M and V), score 0
553482007835	PS00178 Aminoacyl-transfer RNA synthetases class-I signature.
553482007836	Cytidylate kinase-like family; Region: Cytidylate_kin2; pfam13189
553482007837	AAA domain; Region: AAA_17; pfam13207
553482007838	Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis]; Region: RimL; COG1670
553482007839	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
553482007840	HMMPfam hit to PF00583, Acetyltransferase (GNAT) family, score 2.3e-11
553482007841	hypothetical protein; Provisional; Region: PRK07758
553482007842	Predicted helix-turn-helix motif with score 1067.000, SD 2.82 at aa 138-159, sequence WTEAELLALKGIGPATISKLKE
553482007843	Domain of unknown function (DUF1912); Region: DUF1912; pfam08930
553482007844	gene remnan. Similar to an internal region of Streptococcus pyogenes serotype M28 hypothetical exported protein UniProt:Q48S92 (EMBL:CP000056 (452 aa) fasta scores: E()=0.00019, 63.333% id in 30 aa
553482007845	gene remnant. Similar to an internal region of Streptococcus agalactiae DNA-damage-inducible protein J UniProt:Q3DLB5 (EMBL:AAJP01000028 (97 aa) fasta scores: E()=0.0039, 55.000% id in 40 aa
553482007846	3-deoxy-7-phosphoheptulonate synthase; Provisional; Region: PRK13397
553482007847	3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase [Amino acid transport and metabolism]; Region: AroA; COG2876
553482007848	HMMPfam hit to PF00793, DAHP synthetase I family, score 8.8e-84
553482007849	Dehydroquinate synthase (DHQS) catalyzes the conversion of DAHP to DHQ in shikimate pathway for aromatic compounds synthesis; Region: DHQS; cd08195
553482007850	active site
553482007851	dimer interface [polypeptide binding]; other site
553482007852	metal binding site [ion binding]; metal-binding site
553482007853	HMMPfam hit to PF01761, 3-dehydroquinate synthase, score 6.8e-124
553482007854	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2604
553482007855	Phosphorylase superfamily; Region: PNP_UDP_1; pfam01048
553482007856	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482007857	shikimate 5-dehydrogenase; Provisional; Region: PRK12548
553482007858	Shikimate dehydrogenase substrate binding domain; Region: Shikimate_dh_N; pfam08501
553482007859	NAD(P) binding domain of Shikimate dehydrogenase; Region: NAD_bind_Shikimate_DH; cd01065
553482007860	shikimate binding site; other site
553482007861	NAD(P) binding site [chemical binding]; other site
553482007862	HMMPfam hit to PF01488, Shikimate / quinate 5-dehydrogenase, score 9.1e-13
553482007863	PS00579 Ribosomal protein L29 signature.
553482007864	HMMPfam hit to PF08501, Shikimate dehydrogenase substrate bind, score 8.8e-43
553482007865	Beta-galactosidase/beta-glucuronidase [Carbohydrate transport and metabolism]; Region: LacZ; COG3250
553482007866	Glycosyl hydrolases family 2, sugar binding domain; Region: Glyco_hydro_2_N; pfam02837
553482007867	Glycosyl hydrolases family 2; Region: Glyco_hydro_2; pfam00703
553482007868	Glycosyl hydrolases family 2, TIM barrel domain; Region: Glyco_hydro_2_C; pfam02836
553482007869	HMMPfam hit to PF02836, Glycosyl hydrolases family 2, TIM bar, score 6.1e-08
553482007870	HMMPfam hit to PF00703, Glycosyl hydrolases family 2, immunog, score 0.00056
553482007871	HMMPfam hit to PF02837, Glycosyl hydrolases family 2, sugar b, score 1e-46
553482007872	Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain [Signal transduction mechanisms]; Region: COG4753
553482007873	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
553482007874	active site
553482007875	phosphorylation site [posttranslational modification]
553482007876	intermolecular recognition site; other site
553482007877	dimerization interface [polypeptide binding]; other site
553482007878	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
553482007879	HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix pr, score 1.1e-08
553482007880	PS00041 Bacterial regulatory proteins, araC family signature.
553482007881	HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix pr, score 2e-05
553482007882	Predicted helix-turn-helix motif with score 1138.000, SD 3.06 at aa 398-419, sequence LTLKAVSDRLHINGVYLGQRFK
553482007883	HMMPfam hit to PF00072, Response regulator receiver domain, score 5.6e-29
553482007884	Predicted signal transduction protein with a C-terminal ATPase domain [Signal transduction mechanisms]; Region: COG2972
553482007885	HAMP domain; Region: HAMP; pfam00672
553482007886	dimerization interface [polypeptide binding]; other site
553482007887	Histidine kinase; Region: His_kinase; pfam06580
553482007888	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Region: HATPase_c; pfam02518
553482007889	ATP binding site [chemical binding]; other site
553482007890	Mg2+ binding site [ion binding]; other site
553482007891	G-X-G motif; other site
553482007892	HMMPfam hit to PF06580, Histidine kinase, score 1.8e-38
553482007893	HMMPfam hit to PF00672, HAMP domain, score 1.1e-08
553482007894	2 transmembrane helices predicted for SEQ1684 by TMHMM2.0 at aa 26-48 and 280-302
553482007895	Predicted integral membrane protein [Function unknown]; Region: COG5578
553482007896	5 transmembrane helices predicted for SEQ1685 by TMHMM2.0 at aa 20-42, 71-93, 98-120, 140-162 and 169-187
553482007897	HMMPfam hit to PF04854, Protein of unknown function, DUF624, score 5.9e-22
553482007898	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
553482007899	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
553482007900	Domain of unknown function (DUF3502); Region: DUF3502; pfam12010
553482007901	HMMPfam hit to PF01547, Bacterial extracellular solute-binding prot, score 6.4e-09
553482007902	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482007903	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
553482007904	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
553482007905	dimer interface [polypeptide binding]; other site
553482007906	ABC-ATPase subunit interface; other site
553482007907	HMMPfam hit to PF00528, Binding-protein-dependent transport syst, score 9.7e-09
553482007908	6 transmembrane helices predicted for SEQ1687 by TMHMM2.0 at aa 21-43, 85-107, 120-142, 152-174, 195-217 and 274-293
553482007909	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482007910	ABC-type polysaccharide transport system, permease component [Carbohydrate transport and metabolism]; Region: LplB; COG4209
553482007911	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
553482007912	putative PBP binding loops; other site
553482007913	dimer interface [polypeptide binding]; other site
553482007914	ABC-ATPase subunit interface; other site
553482007915	HMMPfam hit to PF00528, Binding-protein-dependent transport syst, score 9.2e-10
553482007916	6 transmembrane helices predicted for SEQ1688 by TMHMM2.0 at aa 20-42, 88-110, 123-145, 175-197, 221-243 and 284-306
553482007917	PS00402 Binding-protein-dependent transport systems inner membrane comp. sign.
553482007918	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
553482007919	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
553482007920	nucleotide binding site [chemical binding]; other site
553482007921	HMMPfam hit to PF00480, ROK family, score 1.6e-23
553482007922	Putative alpha-1,2-mannosidase [Carbohydrate transport and metabolism]; Region: COG3537
553482007923	Glycosyl hydrolase family 92; Region: Glyco_hydro_92; pfam07971
553482007924	PS00343 Gram-positive cocci surface proteins 'anchoring' hexapeptide.
553482007925	HMMPfam hit to PF07971, Glycosyl hydrolase family, score 2e-196
553482007926	Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase [Carbohydrate transport and metabolism]; Region: BglB; COG2723
553482007927	beta-galactosidase; Region: BGL; TIGR03356
553482007928	HMMPfam hit to PF00232, Glycosyl hydrolase family, score 1.6e-94
553482007929	beta-N-acetylglucosaminidase; Region: NAGidase; pfam07555
553482007930	HMMPfam hit to PF07555, Hyaluronidase, score 9e-160
553482007931	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
553482007932	DNA-binding site [nucleotide binding]; DNA binding site
553482007933	Transcriptional regulators [Transcription]; Region: PurR; COG1609
553482007934	Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267
553482007935	ligand binding site [chemical binding]; other site
553482007936	dimerization interface [polypeptide binding]; other site
553482007937	HMMPfam hit to PF00532, Periplasmic binding proteins and sugar b, score 4.5e-05
553482007938	HMMPfam hit to PF00392, Bacterial regulatory proteins, gntR fami, score 3e-22
553482007939	Uncharacterized conserved protein [Function unknown]; Region: COG3538
553482007940	Protein of unknown function (DUF1237); Region: DUF1237; pfam06824
553482007941	HMMPfam hit to PF06824, Protein of unknown function (DUF1237), score 2.5e-304
553482007942	Alpha-mannosidase [Carbohydrate transport and metabolism]; Region: AMS1; COG0383
553482007943	N-terminal catalytic domain of SPGH38, a putative alpha-mannosidase of Streptococcus pyogenes, and its prokaryotic homologs; glycoside hydrolase family 38 (GH38); Region: GH38N_AMII_SpGH38_like; cd10814
553482007944	active site
553482007945	metal binding site [ion binding]; metal-binding site
553482007946	homodimer interface [polypeptide binding]; other site
553482007947	catalytic site [active]
553482007948	Alpha mannosidase, middle domain; Region: Alpha-mann_mid; smart00872
553482007949	HMMPfam hit to PF01074, Glycosyl hydrolases family, score 1.6e-28
553482007950	HMMPfam hit to PF07748, Glycosyl hydrolases family 38 C-termi, score 3.8e-07
553482007951	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
553482007952	putative bacteriocin export ABC transporter, lactococcin 972 group; Region: L_ocin_972_ABC; TIGR03608
553482007953	Walker A/P-loop; other site
553482007954	ATP binding site [chemical binding]; other site
553482007955	Q-loop/lid; other site
553482007956	ABC transporter signature motif; other site
553482007957	Walker B; other site
553482007958	D-loop; other site
553482007959	H-loop/switch region; other site
553482007960	PS00294 Prenyl group binding site (CAAX box).
553482007961	HMMPfam hit to PF00005, ABC transporter, score 1.7e-51
553482007962	PS00211 ABC transporters family signature.
553482007963	PS00017 ATP/GTP-binding site motif A (P-loop).
553482007964	8 transmembrane helices predicted for SEQ1698 by TMHMM2.0 at aa 5-23, 145-167, 196-217, 227-249, 269-288, 558-580, 600-622 and 627-649
553482007965	CDS contains a nonsense mutation (opal) after codon 48. Similar to Streptococcus pyogenes serotype M3 hypothetical exported protein UniProt:Q1JF40 (EMBL:CP000260 (101 aa) fasta scores: E()=4.7e-09, 34.694% id in 98 aa
553482007966	1 transmembrane helix predicted for SEQ1699 by TMHMM2.0 at aa 13-35
553482007967	Sortase and related acyltransferases [Cell envelope biogenesis, outer membrane]; Region: COG1247
553482007968	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
553482007969	Coenzyme A binding pocket [chemical binding]; other site
553482007970	HMMPfam hit to PF00583, Acetyltransferase (GNAT) family, score 2e-09
553482007971	4 transmembrane helices predicted for SEQ1701 by TMHMM2.0 at aa 13-32, 38-60, 77-99 and 109-131
553482007972	putative transposase OrfB; Reviewed; Region: PHA02517
553482007973	HTH-like domain; Region: HTH_21; pfam13276
553482007974	Integrase core domain; Region: rve; pfam00665
553482007975	Integrase core domain; Region: rve_2; pfam13333
553482007976	HMMPfam hit to PF00665, Integrase core domain, score 1.1e-37
553482007977	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
553482007978	Helix-turn-helix domain; Region: HTH_28; pfam13518
553482007979	HMMPfam hit to PF01527, Transposase, score 0.00062
553482007980	HMMPfam hit to PF02178, no description, score 0.21
553482007981	Predicted helix-turn-helix motif with score 1140.000, SD 3.07 at aa 19-40, sequence KSIKCLSEKFSIAESDLKYMIR
553482007982	2 transmembrane helices predicted for SEQ1704 by TMHMM2.0 at aa 5-20 and 41-63
553482007983	1 transmembrane helix predicted for SEQ1705 by TMHMM2.0 at aa 41-63
553482007984	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482007985	Enterocin A Immunity; Region: EntA_Immun; pfam08951
553482007986	A sub-family of peptidase family C39. Peptidase family C39 mostly contains bacteriocin-processing endopeptidases from bacteria. The cysteine peptidases in family C39 cleave the "double-glycine" leader peptides from the precursors of various...; Region: Peptidase_C39B; cd02418
553482007987	ABC-type bacteriocin transporter; Region: bacteriocin_ABC; TIGR01193
553482007988	putative active site [active]
553482007989	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
553482007990	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
553482007991	Walker A/P-loop; other site
553482007992	ATP binding site [chemical binding]; other site
553482007993	Q-loop/lid; other site
553482007994	ABC transporter signature motif; other site
553482007995	Walker B; other site
553482007996	D-loop; other site
553482007997	H-loop/switch region; other site
553482007998	HMMPfam hit to PF03412, Peptidase C39 family, score 2.1e-64
553482007999	4 transmembrane helices predicted for SEQ1709 by TMHMM2.0 at aa 168-190, 202-224, 279-301 and 308-330
553482008000	HMMPfam hit to PF00664, ABC transporter transmembrane region, score 8.3e-63
553482008001	HMMPfam hit to PF00005, ABC transporter, score 4e-52
553482008002	PS00017 ATP/GTP-binding site motif A (P-loop).
553482008003	PS00211 ABC transporters family signature.
553482008004	bacteriocin secretion accessory protein; Region: bacteriocin_acc; TIGR01000
553482008005	HlyD family secretion protein; Region: HlyD_3; pfam13437
553482008006	1 transmembrane helix predicted for SEQ1710 by TMHMM2.0 at aa 19-41
553482008007	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482008008	Double glycine cleavage site bacteriolysin; Region: Antimicrobial16; pfam08128
553482008009	Predicted signal transduction protein with a C-terminal ATPase domain [Signal transduction mechanisms]; Region: COG2972
553482008010	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Region: HATPase_c; pfam02518
553482008011	ATP binding site [chemical binding]; other site
553482008012	Mg2+ binding site [ion binding]; other site
553482008013	G-X-G motif; other site
553482008014	7 transmembrane helices predicted for SEQ1711 by TMHMM2.0 at aa 4-22, 29-51, 55-77, 84-106, 121-142, 162-181 and 191-210
553482008015	Response regulator of the LytR/AlgR family [Transcription / Signal transduction mechanisms]; Region: LytT; COG3279
553482008016	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
553482008017	active site
553482008018	phosphorylation site [posttranslational modification]
553482008019	intermolecular recognition site; other site
553482008020	dimerization interface [polypeptide binding]; other site
553482008021	LytTr DNA-binding domain; Region: LytTR; pfam04397
553482008022	HMMPfam hit to PF04397, LytTr DNA-binding domain, score 8.3e-27
553482008023	HMMPfam hit to PF00072, Response regulator receiver domain, score 9.5e-05
553482008024	1 transmembrane helix predicted for SEQ1713 by TMHMM2.0 at aa 42-64
553482008025	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482008026	Bacteriocin class II with double-glycine leader peptide; Region: Bacteriocin_IIc; pfam10439
553482008027	2 transmembrane helices predicted for SEQ1714 by TMHMM2.0 at aa 34-56 and 60-82
553482008028	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482008029	TRAM domain; Region: TRAM; pfam01938
553482008030	SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase [Translation, ribosomal structure and biogenesis]; Region: TrmA; COG2265
553482008031	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
553482008032	S-adenosylmethionine binding site [chemical binding]; other site
553482008033	HMMPfam hit to PF05958, tRNA (Uracil-5-)-methyltransferase, score 7.8e-06
553482008034	PS00071 Glyceraldehyde 3-phosphate dehydrogenase active site.
553482008035	PS01230 RNA methyltransferase trmA family signature 1.
553482008036	HMMPfam hit to PF01938, TRAM domain, score 2.8e-10
553482008037	Predicted helix-turn-helix motif with score 1096.000, SD 2.92 at aa 293-314, sequence WTTQELLDIPGVGKQMIARLKR
553482008038	recombination regulator RecX; Provisional; Region: recX; PRK14135
553482008039	PS00017 ATP/GTP-binding site motif A (P-loop).
553482008040	HMMPfam hit to PF02631, RecX family, score 3.8e-05
553482008041	hypothetical protein; Provisional; Region: PRK13662
553482008042	HMMPfam hit to PF04167, Protein of unknown function (DUF402), score 1.2e-40
553482008043	Staphylococcal protein of unknown function (DUF960); Region: DUF960; pfam06124
553482008044	Similar to the N-terminal region of Streptococcus suis IS1167 transposase UniProt:Q2ZXS6 (EMBL:AAFA02000136 (191 aa) fasta scores: E()=2.6e-09, 37.736% id in 106 aa
553482008045	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3464
553482008046	Transposase; Region: DDE_Tnp_ISL3; pfam01610
553482008047	Predicted helix-turn-helix motif with score 1838.000, SD 5.45 at aa 119-140, sequence VSMTAIADRLSISTSTVMRKLN
553482008048	HMMPfam hit to PF01610, Transposase, score 2.7e-19
553482008049	RaiA ("ribosome-associated inhibitor A", also known as Protein Y (PY), YfiA, and SpotY,  is a stress-response protein that binds the ribosomal subunit interface and arrests translation by interfering with aminoacyl-tRNA binding to the ribosomal...; Region: RaiA; cd00552
553482008050	30S subunit binding site; other site
553482008051	HMMPfam hit to PF02482, Sigma 54 modulation protein / S30EA r, score 7.5e-31
553482008052	CDS contains a frameshift after codon 9. Similar to Streptococcus pyogenes serotype M3 comF operon protein ComFC UniProt:Q1JKR1 (EMBL:CP000259 (221 aa) fasta scores: E()=1.8e-42, 54.955% id in 222 aa
553482008053	prophage phiSeq3
553482008054	Staphylococcal/Streptococcal toxin, beta-grasp domain; Region: Stap_Strp_tox_C; pfam02876
553482008055	HMMPfam hit to PF02876, Staphylococcal/Streptococcal toxin, b, score 2e-08
553482008056	1 transmembrane helix predicted for SEQ1727 by TMHMM2.0 at aa 12-34
553482008057	Staphylococcal/Streptococcal toxin, beta-grasp domain; Region: Stap_Strp_tox_C; pfam02876
553482008058	HMMPfam hit to PF02876, Staphylococcal/Streptococcal toxin, b, score 2.6e-07
553482008059	Muramidase (flagellum-specific) [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FlgJ; COG1705
553482008060	CHAP domain; Region: CHAP; pfam05257
553482008061	Bacterial SH3 domain; Region: SH3_5; pfam08460
553482008062	HMMPfam hit to PF08460, Bacterial SH3 domain, score 8.5e-09
553482008063	HMMPfam hit to PF05257, CHAP domain, score 1.6e-24
553482008064	HMMPfam hit to PF01832, Mannosyl-glycoprotein endo-beta-N-ace, score 7e-19
553482008065	PS00639 Eukaryotic thiol (cysteine) proteases histidine active site.
553482008066	1 transmembrane helix predicted for SEQ1730 by TMHMM2.0 at aa 21-43
553482008067	1 transmembrane helix predicted for SEQ1731 by TMHMM2.0 at aa 4-26
553482008068	Protein of unknown function (DUF1617); Region: DUF1617; pfam07761
553482008069	HMMPfam hit to PF07761, Protein of unknown function (DUF1617), score 1.2e-93
553482008070	gp58-like protein; Region: Gp58; pfam07902
553482008071	HMMPfam hit to PF07902, gp58-like protein, score 0
553482008072	Collagen triple helix repeat (20 copies); Region: Collagen; pfam01391
553482008073	HMMPfam hit to PF01391, Collagen triple helix repeat (20 copies), score 1.4e-05
553482008074	Prophage endopeptidase tail; Region: Prophage_tail; cl12123
553482008075	Phage-related protein [Function unknown]; Region: COG4722
553482008076	Phage tail protein; Region: Sipho_tail; pfam05709
553482008077	Phage-related protein [Function unknown]; Region: COG5412
553482008078	6 transmembrane helices predicted for SEQ1739 by TMHMM2.0 at aa 500-522, 549-571, 586-608, 621-643, 717-739 and 760-782
553482008079	Phage protein; Region: DUF3647; pfam12363
553482008080	Phage major tail protein 2; Region: Phage_tail_2; cl11463
553482008081	HMMPfam hit to PF06199, Phage major tail protein, score 2.2e-05
553482008082	Phage major tail protein 2; Region: Phage_tail_2; cl11463
553482008083	HMMPfam hit to PF06199, Phage major tail protein, score 1.3e-24
553482008084	Protein of unknown function (DUF3168); Region: DUF3168; pfam11367
553482008085	phage protein, HK97 gp10 family; Region: phge_HK97_gp10; TIGR01725
553482008086	HMMPfam hit to PF07772, TP901-1 ORF40-like protein, score 6.2e-31
553482008087	Phage gp6-like head-tail connector protein; Region: Phage_connect_1; pfam05135
553482008088	Phage major capsid protein E; Region: Phage_cap_E; pfam03864
553482008089	Bacteriophage lambda head decoration protein D; Region: HDPD; pfam02924
553482008090	Domain of unknown function (DUF4355); Region: DUF4355; pfam14265
553482008091	HD domain; Region: HD_4; pfam13328
553482008092	PS00063 Aldo/keto reductase family active site signature.
553482008093	NAD+--asparagine ADP-ribosyltransferase [Signal transduction mechanisms]; Region: COG5585
553482008094	Phage Mu protein F like protein; Region: Phage_Mu_F; cl10072
553482008095	RelA- and SpoT-like ppGpp Synthetases and Hydrolases, catalytic domain; Region: Rel-Spo_like; cl11966
553482008096	metal binding triad [ion binding]; metal-binding site
553482008097	HMMPfam hit to PF04233, Phage Mu protein F like protein, score 2.9e-09
553482008098	phage portal protein, SPP1 family; Region: portal_SPP1; TIGR01538
553482008099	Phage portal protein, SPP1 Gp6-like; Region: Phage_prot_Gp6; pfam05133
553482008100	HMMPfam hit to PF05133, Phage portal protein, SPP1 Gp6-like, score 1.1e-123
553482008101	Phage terminase large subunit; Region: Terminase_3; cl12054
553482008102	Terminase-like family; Region: Terminase_6; pfam03237
553482008103	HMMPfam hit to PF04466, Phage terminase large subunit, score 2.8e-92
553482008104	HMMPfam hit to PF07570, Protein of unknown function (DUF1545), score 9.7e-21
553482008105	PS00017 ATP/GTP-binding site motif A (P-loop).
553482008106	putative transposase OrfB; Reviewed; Region: PHA02517
553482008107	HTH-like domain; Region: HTH_21; pfam13276
553482008108	Integrase core domain; Region: rve; pfam00665
553482008109	Integrase core domain; Region: rve_2; pfam13333
553482008110	HMMPfam hit to PF00665, Integrase core domain, score 8.8e-38
553482008111	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
553482008112	Helix-turn-helix domain; Region: HTH_28; pfam13518
553482008113	HMMPfam hit to PF01527, Transposase, score 0.00062
553482008114	HMMPfam hit to PF02178, no description, score 0.21
553482008115	Predicted helix-turn-helix motif with score 1140.000, SD 3.07 at aa 19-40, sequence KSIKCLSEKFSIAESDLKYMIR
553482008116	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
553482008117	salt bridge; other site
553482008118	non-specific DNA binding site [nucleotide binding]; other site
553482008119	sequence-specific DNA binding site [nucleotide binding]; other site
553482008120	Predicted transcriptional regulator [Transcription]; Region: COG2932
553482008121	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
553482008122	Catalytic site [active]
553482008123	Predicted helix-turn-helix motif with score 1334.000, SD 3.73 at aa 32-53, sequence TKQVELSKATGIPPSTLTGYVK
553482008124	HMMPfam hit to PF00717, Peptidase S24-like, score 5.4e-17
553482008125	Domain of unknown function (DUF4041); Region: DUF4041; pfam13250
553482008126	This entry represents the putative helicase A859L; Region: T5orf172; smart00974
553482008127	Site-specific recombinases, DNA invertase Pin homologs [DNA replication, recombination, and repair]; Region: PinR; COG1961
553482008128	Serine Recombinase (SR) family, Resolvase and Invertase subfamily, catalytic domain; members contain a C-terminal DNA binding domain. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and...; Region: SR_ResInv; cd03768
553482008129	catalytic residues [active]
553482008130	catalytic nucleophile [active]
553482008131	Presynaptic Site I dimer interface [polypeptide binding]; other site
553482008132	Synaptic Antiparallel dimer interface [polypeptide binding]; other site
553482008133	Synaptic Flat tetramer interface [polypeptide binding]; other site
553482008134	Synaptic Site I dimer interface [polypeptide binding]; other site
553482008135	DNA binding site [nucleotide binding]
553482008136	Recombinase; Region: Recombinase; pfam07508
553482008137	Recombinase zinc beta ribbon domain; Region: Zn_ribbon_recom; pfam13408
553482008138	HMMPfam hit to PF00239, Resolvase, N terminal domain, score 2.9e-31
553482008139	PS00397 Site-specific recombinases active site.
553482008140	PS00017 ATP/GTP-binding site motif A (P-loop).
553482008141	HMMPfam hit to PF07508, Recombinase, score 1.4e-25
553482008142	HMMPfam hit to PF00271, Helicase conserved C-terminal domain, score 0.0037
553482008143	PS00017 ATP/GTP-binding site motif A (P-loop).
553482008144	Uncharacterized conserved protein [Function unknown]; Region: COG1739
553482008145	Uncharacterized protein family UPF0029; Region: UPF0029; pfam01205
553482008146	Domain of unknown function (DUF1949); Region: DUF1949; pfam09186
553482008147	HMMPfam hit to PF01205, Uncharacterized protein family UPF0029, score 2.1e-57
553482008148	PS00910 Uncharacterized protein family UPF0029 signature.
553482008149	Cysteine synthase [Amino acid transport and metabolism]; Region: CysK; COG0031
553482008150	CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS is a unique heme-containing enzyme that catalyzes a pyridoxal 5'-phosphate (PLP)-dependent condensation of serine and homocysteine to give cystathionine; Region: CBS_like; cd01561
553482008151	dimer interface [polypeptide binding]; other site
553482008152	pyridoxal 5'-phosphate binding site [chemical binding]; other site
553482008153	catalytic residue [active]
553482008154	HMMPfam hit to PF00291, Pyridoxal-phosphate dependent enzyme, score 1.2e-113
553482008155	PS00901 Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site.
553482008156	hypothetical protein; Provisional; Region: PRK07252
553482008157	Predicted RNA binding protein (contains ribosomal protein S1 domain) [Translation, ribosomal structure and biogenesis]; Region: VacB; COG1098
553482008158	RNA binding site [nucleotide binding]; other site
553482008159	HMMPfam hit to PF00575, S1 RNA binding domain, score 5.7e-15
553482008160	haloacid dehalogenase-like hydrolase; Region: Hydrolase_3; pfam08282
553482008161	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
553482008162	active site
553482008163	motif I; other site
553482008164	motif II; other site
553482008165	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
553482008166	Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family [Posttranslational modification, protein turnover, chaperones]; Region: PpiB; COG0652
553482008167	active site
553482008168	HMMPfam hit to PF00160, Cyclophilin type peptidyl-prolyl cis-tr, score 9.6e-53
553482008169	PS00170 Cyclophilin-type peptidyl-prolyl cis-trans isomerase signature.
553482008170	HMMPfam hit to PF05116, Sucrose-6F-phosphate phosphohydrolase, score 0.0036
553482008171	HMMPfam hit to PF08282, haloacid dehalogenase-like hydrolase, score 5.5e-56
553482008172	HMMPfam hit to PF00702, haloacid dehalogenase-like hydrolase, score 0.0028
553482008173	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
553482008174	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
553482008175	active site
553482008176	phosphorylation site [posttranslational modification]
553482008177	intermolecular recognition site; other site
553482008178	dimerization interface [polypeptide binding]; other site
553482008179	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
553482008180	DNA binding residues [nucleotide binding]
553482008181	dimerization interface [polypeptide binding]; other site
553482008182	HMMPfam hit to PF00196, Bacterial regulatory proteins, luxR fami, score 3.8e-23
553482008183	PS00622 Bacterial regulatory proteins, luxR family signature.
553482008184	HMMPfam hit to PF00072, Response regulator receiver domain, score 7.6e-28
553482008185	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: COG4585
553482008186	Histidine kinase; Region: HisKA_3; pfam07730
553482008187	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
553482008188	ATP binding site [chemical binding]; other site
553482008189	Mg2+ binding site [ion binding]; other site
553482008190	G-X-G motif; other site
553482008191	HMMPfam hit to PF02518, Histidine kinase-, DNA gyrase B-, and HSP90, score 4.3e-13
553482008192	HMMPfam hit to PF07730, Histidine kinase, score 1.1e-22
553482008193	2 transmembrane helices predicted for SEQ1772 by TMHMM2.0 at aa 7-25 and 45-67
553482008194	Predicted membrane protein [Function unknown]; Region: COG4758
553482008195	Cell wall-active antibiotics response protein (DUF2154); Region: DUF2154; pfam09922
553482008196	3 transmembrane helices predicted for SEQ1773 by TMHMM2.0 at aa 7-24, 28-45 and 52-84
553482008197	Serine/Threonine protein kinases, catalytic domain; Region: S_TKc; smart00220
553482008198	Catalytic domain of Protein Kinases; Region: PKc; cd00180
553482008199	active site
553482008200	ATP binding site [chemical binding]; other site
553482008201	substrate binding site [chemical binding]; other site
553482008202	activation loop (A-loop); other site
553482008203	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2815
553482008204	PASTA domain of bacterial serine/threonine kinase pknB-like proteins. PknB is a member of a group of related transmembrane sensor kinases present in many gram positive bacteria, which has been shown to regulate cell shape in Mycobacterium tubercolosis; Region: PASTA_pknB; cd06577
553482008205	PASTA domain of bacterial serine/threonine kinase pknB-like proteins. PknB is a member of a group of related transmembrane sensor kinases present in many gram positive bacteria, which has been shown to regulate cell shape in Mycobacterium tubercolosis; Region: PASTA_pknB; cd06577
553482008206	PASTA domain; Region: PASTA; pfam03793
553482008207	HMMPfam hit to PF03793, PASTA domain, score 6.6e-09
553482008208	HMMPfam hit to PF03793, PASTA domain, score 8.9e-10
553482008209	HMMPfam hit to PF03793, PASTA domain, score 9.2e-11
553482008210	1 transmembrane helix predicted for SEQ1774 by TMHMM2.0 at aa 342-364
553482008211	HMMPfam hit to PF07714, Protein tyrosine kinase, score 6.7e-20
553482008212	HMMPfam hit to PF00069, Protein kinase domain, score 4.1e-55
553482008213	HMMPfam hit to PF01163, RIO1 family, score 0.00073
553482008214	PS00108 Serine/Threonine protein kinases active-site signature.
553482008215	PS00107 Protein kinases ATP-binding region signature.
553482008216	Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and deduced catalytic mechanism of PP2C phosphatases are similar to the PP1, PP2A, PP2B family of protein Ser/Thr phosphatases, with which PP2C shares no sequence...; Region: PP2Cc; cd00143
553482008217	active site
553482008218	HMMPfam hit to PF00481, Protein phosphatase 2C, score 3.8e-07
553482008219	16S rRNA methyltransferase B; Provisional; Region: PRK14902
553482008220	NusB family; Region: NusB; pfam01029
553482008221	putative RNA binding site [nucleotide binding]; other site
553482008222	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
553482008223	S-adenosylmethionine binding site [chemical binding]; other site
553482008224	HMMPfam hit to PF01189, NOL1/NOP2/sun family, score 1.1e-42
553482008225	PS01153 NOL1/NOP2/sun family signature.
553482008226	HMMPfam hit to PF01029, NusB family, score 7.4e-30
553482008227	methionyl-tRNA formyltransferase; Reviewed; Region: fmt; PRK00005
553482008228	Methionyl-tRNA formyltransferase, N-terminal hydrolase domain; Region: FMT_core_Met-tRNA-FMT_N; cd08646
553482008229	putative active site [active]
553482008230	substrate binding site [chemical binding]; other site
553482008231	putative cosubstrate binding site; other site
553482008232	catalytic site [active]
553482008233	C-terminal domain of Formyltransferase and other enzymes; Region: Met_tRNA_FMT_C; cd08704
553482008234	substrate binding site [chemical binding]; other site
553482008235	HMMPfam hit to PF02911, Formyl transferase, C-terminal domain, score 2.3e-35
553482008236	HMMPfam hit to PF00551, Formyl transferase, score 1.4e-36
553482008237	Primosomal protein N' (replication factor Y) - superfamily II helicase [DNA replication, recombination, and repair]; Region: PriA; COG1198
553482008238	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
553482008239	ATP binding site [chemical binding]; other site
553482008240	putative Mg++ binding site [ion binding]; other site
553482008241	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
553482008242	ATP-binding site [chemical binding]; other site
553482008243	HMMPfam hit to PF00271, Helicase conserved C-terminal domain, score 6.1e-07
553482008244	HMMPfam hit to PF00270, DEAD/DEAH box helicase, score 7.1e-25
553482008245	HMMPfam hit to PF04851, Type III restriction enzyme, res subunit, score 3.5e-29
553482008246	PS00017 ATP/GTP-binding site motif A (P-loop).
553482008247	DNA-directed RNA polymerase subunit omega; Reviewed; Region: rpoZ; PRK00392
553482008248	HMMPfam hit to PF01192, RNA polymerase Rpb6, score 4e-14
553482008249	Guanylate kinase [Nucleotide transport and metabolism]; Region: Gmk; COG0194
553482008250	Guanosine monophosphate kinase (GMPK, EC 2.7.4.8), also known as guanylate kinase (GKase), catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to guanosine monophosphate (GMP) to yield adenosine diphosphate (ADP) and guanosine...; Region: GMPK; cd00071
553482008251	catalytic site [active]
553482008252	G-X2-G-X-G-K; other site
553482008253	HMMPfam hit to PF00625, Guanylate kinase, score 3.5e-46
553482008254	hypothetical protein; Provisional; Region: PRK00106
553482008255	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
553482008256	Zn2+ binding site [ion binding]; other site
553482008257	Mg2+ binding site [ion binding]; other site
553482008258	HMMPfam hit to PF01966, HD domain, score 8.3e-24
553482008259	HMMPfam hit to PF00013, KH domain, score 4.3e-10
553482008260	1 transmembrane helix predicted for SEQ1781 by TMHMM2.0 at aa 2-24
553482008261	S-ribosylhomocysteinase; Provisional; Region: PRK02260
553482008262	HMMPfam hit to PF02664, S-Ribosylhomocysteinase (LuxS), score 1.2e-44
553482008263	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
553482008264	Helix-turn-helix domain; Region: HTH_28; pfam13518
553482008265	Predicted helix-turn-helix motif with score 1140.000, SD 3.07 at aa 19-40, sequence KSIKCLSEKFSIAESDLKYMIR
553482008266	HMMPfam hit to PF01527, Transposase, score 0.00062
553482008267	HMMPfam hit to PF02178, no description, score 0.21
553482008268	putative transposase OrfB; Reviewed; Region: PHA02517
553482008269	HTH-like domain; Region: HTH_21; pfam13276
553482008270	Integrase core domain; Region: rve; pfam00665
553482008271	Integrase core domain; Region: rve_2; pfam13333
553482008272	HMMPfam hit to PF00665, Integrase core domain, score 1.1e-37
553482008273	1 transmembrane helix predicted for SEQ1785 by TMHMM2.0 at aa 168-190
553482008274	Predicted N6-adenine-specific DNA methylase [DNA replication, recombination, and repair]; Region: COG0116
553482008275	THUMP domain associated with S-adenosylmethionine-dependent methyltransferases; Region: THUMP_AdoMetMT; cd11715
553482008276	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
553482008277	HMMPfam hit to PF01170, RNA methylase family UPF0020, score 1.1e-64
553482008278	PS00092 N-6 Adenine-specific DNA methylases signature.
553482008279	cell division protein GpsB; Provisional; Region: PRK14127
553482008280	DivIVA domain; Region: DivI1A_domain; TIGR03544
553482008281	HMMPfam hit to PF05103, DivIVA protein, score 1e-27
553482008282	hypothetical protein; Provisional; Region: PRK13660
553482008283	HMMPfam hit to PF06908, Protein of unknown function (DUF1273), score 6e-105
553482008284	Holliday junction-specific endonuclease; Reviewed; Region: recU; PRK02234
553482008285	PS00030 Eukaryotic RNA-binding region RNP-1 signature.
553482008286	Membrane carboxypeptidase (penicillin-binding protein) [Cell envelope biogenesis, outer membrane]; Region: MrcB; COG0744
553482008287	Transglycosylase; Region: Transgly; pfam00912
553482008288	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
553482008289	1 transmembrane helix predicted for SEQ1790 by TMHMM2.0 at aa 17-39
553482008290	HMMPfam hit to PF00912, Transglycosylase, score 7.5e-84
553482008291	HMMPfam hit to PF00905, Penicillin binding protein transpeptid, score 8.3e-20
553482008292	PS00017 ATP/GTP-binding site motif A (P-loop).
553482008293	Peptidase C1B subfamily (MEROPS database nomenclature); composed of eukaryotic bleomycin hydrolases (BH) and bacterial aminopeptidases C (pepC). The proteins of this subfamily contain a large insert relative to the C1A peptidase (papain) subfamily. BH is...; Region: Peptidase_C1B; cd00585
553482008294	trimer interface [polypeptide binding]; other site
553482008295	active site
553482008296	G bulge; other site
553482008297	HMMPfam hit to PF03051, Peptidase C1-like family, score 7.2e-300
553482008298	PS00639 Eukaryotic thiol (cysteine) proteases histidine active site.
553482008299	PS00017 ATP/GTP-binding site motif A (P-loop).
553482008300	PS00139 Eukaryotic thiol (cysteine) proteases cysteine active site.
553482008301	NAD synthase [Coenzyme metabolism]; Region: NadE; COG0171
553482008302	NAD+ synthase is a homodimer, which catalyzes the final step in de novo nicotinamide adenine dinucleotide (NAD+) biosynthesis, an amide transfer from either ammonia or glutamine to nicotinic acid adenine dinucleotide (NaAD). The conversion of NaAD to NAD...; Region: NAD_synthase; cd00553
553482008303	homodimer interface [polypeptide binding]; other site
553482008304	NAD binding pocket [chemical binding]; other site
553482008305	ATP binding pocket [chemical binding]; other site
553482008306	Mg binding site [ion binding]; other site
553482008307	active-site loop [active]
553482008308	HMMPfam hit to PF02540, NAD synthase, score 4.1e-100
553482008309	nicotinate phosphoribosyltransferase; Validated; Region: PRK09243
553482008310	Nicotinate phosphoribosyltransferase (NAPRTase), subgroup A. Nicotinate phosphoribosyltransferase catalyses the formation of NAMN and PPi from 5-phosphoribosy -1-pyrophosphate (PRPP) and nicotinic acid, this is the first, and also rate limiting, reaction...; Region: NAPRTase_A; cd01570
553482008311	active site
553482008312	HMMPfam hit to PF04095, Nicotinate phosphoribosyltransferase (NAPRTa, score 3.7e-10
553482008313	Gamma-aminobutyrate permease and related permeases [Amino acid transport and metabolism]; Region: AnsP; COG1113
553482008314	HMMPfam hit to PF00324, Amino acid permease, score 1.5e-86
553482008315	12 transmembrane helices predicted for SEQ1794 by TMHMM2.0 at aa 26-48, 53-72, 92-114, 129-151, 158-180, 210-232, 252-270, 290-312, 342-364, 374-396, 409-431 and 436-453
553482008316	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482008317	PS00218 Amino acid permeases signature.
553482008318	thioredoxin-disulfide reductase; Region: TRX_reduct; TIGR01292
553482008319	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
553482008320	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
553482008321	HMMPfam hit to PF07992, Pyridine nucleotide-disulphide oxidoreduc, score 4.6e-41
553482008322	HMMPfam hit to PF00070, Pyridine nucleotide-disulphide oxidoreduc, score 7.1e-25
553482008323	PS00573 Pyridine nucleotide-disulphide oxidoreductases class-II active site.
553482008324	Protein of unknown function (DUF4059); Region: DUF4059; pfam13268
553482008325	2 transmembrane helices predicted for SEQ1796 by TMHMM2.0 at aa 13-30 and 50-72
553482008326	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
553482008327	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
553482008328	Walker A/P-loop; other site
553482008329	ATP binding site [chemical binding]; other site
553482008330	Q-loop/lid; other site
553482008331	ABC transporter signature motif; other site
553482008332	Walker B; other site
553482008333	D-loop; other site
553482008334	H-loop/switch region; other site
553482008335	HMMPfam hit to PF00005, ABC transporter, score 8.6e-69
553482008336	PS00211 ABC transporters family signature.
553482008337	PS00017 ATP/GTP-binding site motif A (P-loop).
553482008338	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
553482008339	dimer interface [polypeptide binding]; other site
553482008340	conserved gate region; other site
553482008341	putative PBP binding loops; other site
553482008342	ABC-ATPase subunit interface; other site
553482008343	HMMPfam hit to PF00528, Binding-protein-dependent transport syst, score 3e-17
553482008344	PS00402 Binding-protein-dependent transport systems inner membrane comp. sign.
553482008345	Predicted helix-turn-helix motif with score 1013.000, SD 2.64 at aa 165-186, sequence TGEIEAAKSLGMTSAQVYRRVI
553482008346	3 transmembrane helices predicted for SEQ1798 by TMHMM2.0 at aa 57-79, 92-114 and 129-151
553482008347	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
553482008348	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
553482008349	substrate binding pocket [chemical binding]; other site
553482008350	membrane-bound complex binding site; other site
553482008351	hinge residues; other site
553482008352	HMMPfam hit to PF00497, Bacterial extracellular solute-binding prot, score 5.4e-50
553482008353	1 transmembrane helix predicted for SEQ1799 by TMHMM2.0 at aa 7-29
553482008354	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
553482008355	DEAD-like helicases superfamily; Region: DEXDc; smart00487
553482008356	ATP binding site [chemical binding]; other site
553482008357	Mg++ binding site [ion binding]; other site
553482008358	motif III; other site
553482008359	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
553482008360	nucleotide binding region [chemical binding]; other site
553482008361	ATP-binding site [chemical binding]; other site
553482008362	HMMPfam hit to PF00271, Helicase conserved C-terminal domain, score 3.5e-26
553482008363	HMMPfam hit to PF00270, DEAD/DEAH box helicase, score 2.7e-53
553482008364	phospho-N-acetylmuramoyl-pentapeptide-transferase; Provisional; Region: mraY; PRK00108
553482008365	Phospho-N-acetylmuramoyl-pentapeptide-transferase (mraY) is an enzyme responsible for the formation of the first lipid intermediate in the synthesis of bacterial cell wall peptidoglycan. It catalyzes the formation of...; Region: GT_MraY; cd06852
553482008366	Mg++ binding site [ion binding]; other site
553482008367	putative catalytic motif [active]
553482008368	putative substrate binding site [chemical binding]; other site
553482008369	10 transmembrane helices predicted for SEQ1802 by TMHMM2.0 at aa 4-26, 47-69, 79-98, 119-138, 148-170, 177-196, 200-219, 226-248, 252-274 and 317-334
553482008370	HMMPfam hit to PF00953, Glycosyl transferase family, score 1.5e-59
553482008371	Cell division protein FtsI/penicillin-binding protein 2 [Cell envelope biogenesis, outer membrane]; Region: FtsI; COG0768
553482008372	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
553482008373	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
553482008374	PASTA domain of PBP2x-like proteins, first repeat. Penicillin-binding proteins (PBPs) are the major targets for beta-lactam antibiotics, like penicillins and cephalosporins. Beta-lactam antibiotics specifically inhibit transpeptidase activity by...; Region: PASTA_Pbp2x-like_1; cd06576
553482008375	PASTA domain of PBP2x-like proteins, second repeat. Penicillin-binding proteins (PBPs) are the major targets for beta-lactam antibiotics, like penicillins and cephalosporins. Beta-lactam antibiotics specifically inhibit transpeptidase activity by...; Region: PASTA_Pbp2x-like_2; cd06575
553482008376	HMMPfam hit to PF03793, PASTA domain, score 1.5e-10
553482008377	HMMPfam hit to PF03793, PASTA domain, score 6.9e-07
553482008378	HMMPfam hit to PF00905, Penicillin binding protein transpeptid, score 1.2e-90
553482008379	HMMPfam hit to PF03717, Penicillin-binding Protein dimerisatio, score 6e-46
553482008380	PS00430 TonB-dependent receptor proteins signature 1.
553482008381	1 transmembrane helix predicted for SEQ1803 by TMHMM2.0 at aa 26-48
553482008382	Protein required for the initiation of cell division [Cell division and chromosome partitioning]; Region: FtsL; COG4839
553482008383	HMMPfam hit to PF04977, Septum formation initiator, score 0.00019
553482008384	1 transmembrane helix predicted for SEQ1804 by TMHMM2.0 at aa 27-46
553482008385	Predicted S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis [Cell envelope biogenesis, outer membrane]; Region: COG0275
553482008386	MraW methylase family; Region: Methyltransf_5; pfam01795
553482008387	HMMPfam hit to PF01795, MraW methylase family, score 8.9e-191
553482008388	Gamma-glutamyl phosphate reductase (GPR), aldehyde dehydrogenase families 18 and 19; Region: ALDH_F18-19_ProA-GPR; cd07079
553482008389	gamma-glutamyl phosphate reductase; Region: proA; TIGR00407
553482008390	putative catalytic cysteine [active]
553482008391	Glutamate 5-kinase [Amino acid transport and metabolism]; Region: ProB; COG0263
553482008392	AAK_G5K_ProB: Glutamate-5-kinase (G5K) catalyzes glutamate-dependent ATP cleavage; G5K transfers the terminal phosphoryl group of ATP to the gamma-carboxyl group of glutamate, in the first and controlling step of proline (and, in mammals, ornithine)...; Region: AAK_G5K_ProB; cd04242
553482008393	nucleotide binding site [chemical binding]; other site
553482008394	homotetrameric interface [polypeptide binding]; other site
553482008395	putative phosphate binding site [ion binding]; other site
553482008396	putative allosteric binding site; other site
553482008397	HMMPfam hit to PF00696, Amino acid kinase family, score 4.5e-61
553482008398	1 transmembrane helix predicted for SEQ1810 by TMHMM2.0 at aa 10-25
553482008399	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
553482008400	Helix-turn-helix domain; Region: HTH_28; pfam13518
553482008401	Predicted helix-turn-helix motif with score 1140.000, SD 3.07 at aa 19-40, sequence KSIKCLSEKFSIAESDLKYMIR
553482008402	HMMPfam hit to PF01527, Transposase, score 0.00062
553482008403	HMMPfam hit to PF02178, no description, score 0.21
553482008404	putative transposase OrfB; Reviewed; Region: PHA02517
553482008405	HTH-like domain; Region: HTH_21; pfam13276
553482008406	Integrase core domain; Region: rve; pfam00665
553482008407	Integrase core domain; Region: rve_2; pfam13333
553482008408	HMMPfam hit to PF00665, Integrase core domain, score 1.1e-37
553482008409	12 transmembrane helices predicted for SEQ1814 by TMHMM2.0 at aa 48-65, 75-97, 125-147, 152-174, 190-212, 248-267, 319-341, 356-378, 407-429, 433-455, 479-501 and 511-531
553482008410	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482008411	PS00095 C-5 cytosine-specific DNA methylases C-terminal signature.
553482008412	ABC-type Na+ transport system, ATPase component [Energy production and conversion / Inorganic ion transport and metabolism]; Region: NatA; COG4555
553482008413	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
553482008414	Walker A/P-loop; other site
553482008415	ATP binding site [chemical binding]; other site
553482008416	Q-loop/lid; other site
553482008417	ABC transporter signature motif; other site
553482008418	Walker B; other site
553482008419	D-loop; other site
553482008420	H-loop/switch region; other site
553482008421	HMMPfam hit to PF00005, ABC transporter, score 5.6e-42
553482008422	PS00211 ABC transporters family signature.
553482008423	PS00017 ATP/GTP-binding site motif A (P-loop).
553482008424	Enterocin A Immunity; Region: EntA_Immun; pfam08951
553482008425	Collagen triple helix repeat (20 copies); Region: Collagen; pfam01391
553482008426	Gram positive anchor; Region: Gram_pos_anchor; pfam00746
553482008427	1 transmembrane helix predicted for SEQ1817 by TMHMM2.0 at aa 9-31
553482008428	HMMPfam hit to PF01391, Collagen triple helix repeat (20 copi, score 6.5e-11
553482008429	HMMPfam hit to PF01391, Collagen triple helix repeat (20 copi, score 2.3e-14
553482008430	HMMPfam hit to PF01391, Collagen triple helix repeat (20 copi, score 2.5e-15
553482008431	HMMPfam hit to PF01391, Collagen triple helix repeat (20 copi, score 1.6e-14
553482008432	HMMPfam hit to PF01391, Collagen triple helix repeat (20 copi, score 5e-12
553482008433	HMMPfam hit to PF00746, Gram positive anchor, score 6.2e-12
553482008434	PS00343 Gram-positive cocci surface proteins 'anchoring' hexapeptide.
553482008435	Transketolase [Carbohydrate transport and metabolism]; Region: TktA; COG0021
553482008436	Thiamine pyrophosphate (TPP) family, Transketolase (TK) subfamily, TPP-binding module; TK catalyzes the transfer of a two-carbon unit from ketose phosphates to aldose phosphates. In heterotrophic organisms, TK provides a link between glycolysis and the...; Region: TPP_TK; cd02012
553482008437	TPP-binding site [chemical binding]; other site
553482008438	dimer interface [polypeptide binding]; other site
553482008439	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
553482008440	PYR/PP interface [polypeptide binding]; other site
553482008441	dimer interface [polypeptide binding]; other site
553482008442	TPP binding site [chemical binding]; other site
553482008443	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
553482008444	HMMPfam hit to PF02780, Transketolase, C-terminal domain, score 0.00029
553482008445	HMMPfam hit to PF02779, Transketolase, pyridine binding domai, score 9.9e-63
553482008446	PS00802 Transketolase signature 2.
553482008447	HMMPfam hit to PF00456, Transketolase, thiamine diphosphate b, score 6.1e-202
553482008448	PS00801 Transketolase signature 1.
553482008449	Transaldolase-like fructose-6-phosphate aldolases (FSA) found in bacteria and archaea; Region: Transaldolase_FSA; cd00956
553482008450	active site
553482008451	intersubunit interactions; other site
553482008452	catalytic residue [active]
553482008453	HMMPfam hit to PF00923, Transaldolase, score 7.1e-53
553482008454	PS01054 Transaldolase signature 1.
553482008455	glycerol kinase; Provisional; Region: glpK; PRK00047
553482008456	Escherichia coli glycerol kinase-like proteins; belongs to the FGGY family of carbohydrate kinases; Region: FGGY_EcGK_like; cd07786
553482008457	N- and C-terminal domain interface [polypeptide binding]; other site
553482008458	active site
553482008459	MgATP binding site [chemical binding]; other site
553482008460	catalytic site [active]
553482008461	metal binding site [ion binding]; metal-binding site
553482008462	glycerol binding site [chemical binding]; other site
553482008463	homotetramer interface [polypeptide binding]; other site
553482008464	homodimer interface [polypeptide binding]; other site
553482008465	FBP binding site [chemical binding]; other site
553482008466	protein IIAGlc interface [polypeptide binding]; other site
553482008467	PS00014 Endoplasmic reticulum targeting sequence.
553482008468	HMMPfam hit to PF02782, FGGY family of carbohydrate kinases, C-termi, score 1.2e-76
553482008469	PS00445 FGGY family of carbohydrate kinases signature 2.
553482008470	HMMPfam hit to PF00370, FGGY family of carbohydrate kinases, N-termi, score 3e-116
553482008471	PS00933 FGGY family of carbohydrate kinases signature 1.
553482008472	Predicted membrane protein [Function unknown]; Region: COG3212
553482008473	Peptidase propeptide and YPEB domain; Region: PepSY; pfam03413
553482008474	Peptidase propeptide and YPEB domain; Region: PepSY; pfam03413
553482008475	HMMPfam hit to PF03413, Peptidase propeptide and YPEB domain, score 0.0015
553482008476	HMMPfam hit to PF03413, Peptidase propeptide and YPEB domain, score 0.00039
553482008477	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482008478	2 transmembrane helices predicted for SEQ1822 by TMHMM2.0 at aa 2-19 and 29-63
553482008479	gene remnant
553482008480	Predicted methyltransferases [General function prediction only]; Region: COG0313
553482008481	Ribosomal RNA small subunit methyltransferase I, also known as rRNA (cytidine-2'-O-)-methyltransferase RsmI; Region: RsmI; cd11648
553482008482	putative SAM binding site [chemical binding]; other site
553482008483	putative homodimer interface [polypeptide binding]; other site
553482008484	HMMPfam hit to PF00590, Tetrapyrrole (Corrin/Porphyrin) Methylas, score 7.6e-40
553482008485	PS01296 Uncharacterized protein family UPF0011 signature.
553482008486	DNA replication intiation control protein YabA; Reviewed; Region: PRK13169
553482008487	HMMPfam hit to PF06156, Protein of unknown function (DUF972), score 3.9e-63
553482008488	PSP1 C-terminal conserved region; Region: PSP1; cl00770
553482008489	HMMPfam hit to PF04468, PSP1 C-terminal conserved region, score 2.7e-26
553482008490	DNA polymerase III subunit delta'; Validated; Region: PRK07276
553482008491	DNA polymerase III subunit delta'; Validated; Region: PRK08485
553482008492	thymidylate kinase; Validated; Region: tmk; PRK00698
553482008493	Thymidine monophosphate kinase (TMPK), also known as thymidylate kinase, catalyzes the phosphorylation of thymidine monophosphate (TMP) to thymidine diphosphate (TDP) utilizing ATP as its preferred phophoryl donor. TMPK represents the rate-limiting step...; Region: TMPK; cd01672
553482008494	TMP-binding site; other site
553482008495	ATP-binding site [chemical binding]; other site
553482008496	HMMPfam hit to PF02223, Thymidylate kinase, score 6.6e-67
553482008497	PS01331 Thymidylate kinase signature.
553482008498	PS00017 ATP/GTP-binding site motif A (P-loop).
553482008499	hypothetical protein; Provisional; Region: PRK02302
553482008500	Protein of unknown function (DUF964); Region: DUF964; pfam06133
553482008501	HMMPfam hit to PF07050, Protein of unknown function (DUF1333), score 2.3e-25
553482008502	Protease subunit of ATP-dependent Clp proteases [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: ClpP; COG0740
553482008503	Caseinolytic protease (ClpP) is an ATP-dependent, highly conserved serine protease; Region: S14_ClpP_2; cd07017
553482008504	oligomer interface [polypeptide binding]; other site
553482008505	active site residues [active]
553482008506	HMMPfam hit to PF00574, Clp protease, score 5.3e-120
553482008507	PS00382 Endopeptidase Clp histidine active site.
553482008508	PS00381 Endopeptidase Clp serine active site.
553482008509	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
553482008510	active site
553482008511	HMMPfam hit to PF00156, Phosphoribosyl transferase domain, score 4.3e-15
553482008512	Membrane protein involved in the export of O-antigen and teichoic acid [General function prediction only]; Region: RfbX; COG2244
553482008513	Stage V sporulation protein B, also known as Stage III sporulation protein F, and related proteins; Region: MATE_SpoVB_like; cd13124
553482008514	12 transmembrane helices predicted for SEQ1834 by TMHMM2.0 at aa 21-43, 58-77, 98-117, 132-154, 194-216, 302-324, 336-358, 373-395, 407-426, 431-448, 468-490 and 500-522
553482008515	HMMPfam hit to PF01943, Polysaccharide biosynthesis protein, score 9.1e-10
553482008516	UDP-N-acetylmuramoylalanyl-D-glutamate--L-lysine ligase; Provisional; Region: PRK14022
553482008517	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
553482008518	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
553482008519	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
553482008520	HMMPfam hit to PF01225, Mur ligase family, catalytic domain, score 0.0075
553482008521	HMMPfam hit to PF08245, Mur ligase middle domain, score 2.9e-34
553482008522	HMMPfam hit to PF02875, Mur ligase family, glutamate ligase doma, score 2.2e-19
553482008523	PS00030 Eukaryotic RNA-binding region RNP-1 signature.
553482008524	ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components [Inorganic ion transport and metabolism / Coenzyme metabolism]; Region: FepC; COG1120
553482008525	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
553482008526	Walker A/P-loop; other site
553482008527	ATP binding site [chemical binding]; other site
553482008528	Q-loop/lid; other site
553482008529	ABC transporter signature motif; other site
553482008530	Walker B; other site
553482008531	D-loop; other site
553482008532	H-loop/switch region; other site
553482008533	HMMPfam hit to PF00005, ABC transporter, score 6.4e-49
553482008534	PS00017 ATP/GTP-binding site motif A (P-loop).
553482008535	PS00211 ABC transporters family signature.
553482008536	ABC-type Fe3+-hydroxamate transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: FepB; COG0614
553482008537	Periplasmic binding protein FeuA.  These proteins have predicted to function as initial receptors in ABC transport of metal ions in some eubacterial species.  They belong to the TroA superfamily of periplasmic metal binding proteins that share a distinct...; Region: FeuA; cd01138
553482008538	putative ligand binding residues [chemical binding]; other site
553482008539	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482008540	HMMPfam hit to PF01497, Periplasmic binding protein, score 9.6e-41
553482008541	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
553482008542	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
553482008543	ABC-ATPase subunit  interface; other site
553482008544	dimer interface [polypeptide binding]; other site
553482008545	putative PBP binding regions; other site
553482008546	10 transmembrane helices predicted for SEQ1838 by TMHMM2.0 at aa 19-41, 68-90, 103-120, 125-147, 160-179, 184-201, 206-228, 243-274, 286-303 and 318-335
553482008547	HMMPfam hit to PF01032, FecCD transport family, score 3.5e-94
553482008548	ABC-type enterobactin transport system, permease component [Inorganic ion transport and metabolism]; Region: FepG; COG4779
553482008549	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
553482008550	ABC-ATPase subunit  interface; other site
553482008551	dimer interface [polypeptide binding]; other site
553482008552	putative PBP binding regions; other site
553482008553	9 transmembrane helices predicted for SEQ1839 by TMHMM2.0 at aa 7-29, 57-79, 92-109, 119-141, 148-170, 198-220, 241-263, 283-305 and 312-329
553482008554	HMMPfam hit to PF01032, FecCD transport family, score 1.8e-80
553482008555	PS00215 Mitochondrial energy transfer proteins signature.
553482008556	Domain of unknown function (DUF1803); Region: DUF1803; pfam08820
553482008557	Domain of unknown function (DUF1803); Region: DUF1803; pfam08820
553482008558	putative manganese-dependent inorganic pyrophosphatase; Provisional; Region: PRK05427
553482008559	DHH family; Region: DHH; pfam01368
553482008560	DHHA2 domain; Region: DHHA2; pfam02833
553482008561	HMMPfam hit to PF02833, DHHA2 domain, score 4e-53
553482008562	HMMPfam hit to PF01368, DHH family, score 6e-16
553482008563	pyruvate formate-lyase 1-activating enzyme; Region: PFLA; TIGR02493
553482008564	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
553482008565	FeS/SAM binding site; other site
553482008566	PS01087 Radical activating enzymes signature.
553482008567	PS00190 Cytochrome c family heme-binding site signature.
553482008568	Hemolysins and related proteins containing CBS domains [General function prediction only]; Region: TlyC; COG1253
553482008569	Domain of unknown function DUF21; Region: DUF21; pfam01595
553482008570	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
553482008571	Transporter associated domain; Region: CorC_HlyC; smart01091
553482008572	HMMPfam hit to PF03471, Transporter associated domain, score 6.8e-23
553482008573	HMMPfam hit to PF00571, CBS domain pair, score 4e-24
553482008574	HMMPfam hit to PF01595, Domain of unknown function DUF21, score 2.2e-73
553482008575	4 transmembrane helices predicted for SEQ1844 by TMHMM2.0 at aa 10-29, 71-93, 103-125 and 137-159
553482008576	Putative rRNA methylase; Region: rRNA_methylase; pfam06962
553482008577	HMMPfam hit to PF06962, rRNA methylase, score 9.1e-81
553482008578	Phosphotransferase enzyme family; Region: APH; pfam01636
553482008579	Aminoglycoside 3'-phosphotransferase (APH). The APH subfamily is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs), RIO kinases, actin-fragmin...; Region: APH; cd05150
553482008580	active site
553482008581	ATP binding site [chemical binding]; other site
553482008582	antibiotic binding site [chemical binding]; other site
553482008583	HMMPfam hit to PF01636, Phosphotransferase enzyme family, score 2.1e-18
553482008584	PS00109 Tyrosine protein kinases specific active-site signature.
553482008585	Predicted Fe-S oxidoreductase [General function prediction only]; Region: COG1242
553482008586	PAP2_like_2 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This subgroup, which is specific to bacteria, lacks functional characterization and may act as a membrane-associated lipid phosphatase; Region: PAP2_like_2; cd03392
553482008587	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
553482008588	active site
553482008589	6 transmembrane helices predicted for SEQ1848 by TMHMM2.0 at aa 7-29, 58-80, 87-109, 124-146, 153-175 and 185-202
553482008590	Predicted membrane protein [Function unknown]; Region: COG3601
553482008591	Protein of unknown function (DUF3816); Region: DUF3816; pfam12822
553482008592	5 transmembrane helices predicted for SEQ1849 by TMHMM2.0 at aa 15-37, 44-66, 86-105, 117-139 and 159-181
553482008593	PS00225 Crystallins beta and gamma 'Greek key' motif signature.
553482008594	Lipase.  Lipases are esterases that can hydrolyze long-chain acyl-triglycerides into di- and monoglycerides, glycerol, and free fatty acids at a water/lipid interface. A typical feature of lipases is "interfacial activation", the process of...; Region: Lipase; cl14883
553482008595	nucleophilic elbow; other site
553482008596	catalytic triad; other site
553482008597	PS00120 Lipases, serine active site.
553482008598	1 transmembrane helix predicted for SEQ1853 by TMHMM2.0 at aa 12-31
553482008599	gene remnant. Similar to the N-terminal region of Streptococcus agalactiae serotype III hypothetical protein GBS1967 UniProt:Q8E2Z6 (EMBL:AL766855 (402 aa) fasta scores: E()=0.024, 35.366% id in 82 aa. Similar to the N-terminal region of SEQ1052, 52.000% identity (53.425% ungapped) in 75 aa overlap (5-79:3-75)
553482008600	gene remnant. Similar to the N-terminal region of Streptococcus agalactiae CJB111 uncharacterized protein UniProt:Q3DDH3 (EMBL:AAJQ01000032) (71 aa) fasta scores: E()=0.61, 38.182% id in 55 aa
553482008601	1 transmembrane helix predicted for SEQ1857 by TMHMM2.0 at aa 15-34
553482008602	Predicted rRNA methylase (SpoU class) [Translation, ribosomal structure and biogenesis]; Region: CspR; COG0219
553482008603	HMMPfam hit to PF00588, SpoU rRNA Methylase family, score 5.2e-42
553482008604	hypothetical protein; Validated; Region: PRK00041
553482008605	HMMPfam hit to PF01809, Domain of unknown function DUF37, score 8.6e-35
553482008606	16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases [Translation, ribosomal structure and biogenesis]; Region: RsuA; COG1187
553482008607	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
553482008608	RNA binding surface [nucleotide binding]; other site
553482008609	Pseudouridine synthases, RsuA subfamily; Region: PseudoU_synth_RsuA_like; cd02870
553482008610	active site
553482008611	HMMPfam hit to PF00849, RNA pseudouridylate synthase, score 1.1e-23
553482008612	PS01149 Rsu family of pseudouridine synthase signature.
553482008613	HMMPfam hit to PF01479, S4 domain, score 3.5e-15
553482008614	segregation and condensation protein B; Reviewed; Region: scpB; PRK00135
553482008615	HMMPfam hit to PF04079, transcriptional regulators (Ypuh-li, score 3.1e-75
553482008616	Predicted helix-turn-helix motif with score 1232.000, SD 3.38 at aa 19-40, sequence LSLRQLASLLELTPTALQQQLD
553482008617	segregation and condensation protein A; Reviewed; Region: scpA; PRK00104
553482008618	HMMPfam hit to PF02616, ScpA/B protein, score 1.1e-22
553482008619	site-specific tyrosine recombinase XerD-like protein; Reviewed; Region: xerD; PRK02436
553482008620	DNA breaking-rejoining enzymes, intergrase/recombinases, C-terminal catalytic domain. The tyrosine recombinase/integrase family share the same catalytic domain containing six conserved active site residues. The best-studied members of this diverse family...; Region: INT_REC_C; cd01182
553482008621	DNA binding site [nucleotide binding]
553482008622	active site
553482008623	Int/Topo IB signature motif; other site
553482008624	catalytic residues [active]
553482008625	HMMPfam hit to PF00589, Phage integrase family, score 0.02
553482008626	The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called...; Region: CBS_pair_30; cd04643
553482008627	FOG: CBS domain [General function prediction only]; Region: COG0517
553482008628	HMMPfam hit to PF00571, CBS domain pair, score 3.7e-21
553482008629	Escherichia coli YfcE and related proteins, metallophosphatase domain; Region: MPP_YfcE; cd00841
553482008630	active site
553482008631	metal binding site [ion binding]; metal-binding site
553482008632	homotetramer interface [polypeptide binding]; other site
553482008633	PS00017 ATP/GTP-binding site motif A (P-loop).
553482008634	HMMPfam hit to PF00149, Calcineurin-like phosphoesterase, score 0.00011
553482008635	putative deoxyribonucleotide triphosphate pyrophosphatase/unknown domain fusion protein; Reviewed; Region: PRK02491
553482008636	NTPase/HAM1.  This family consists of the HAM1 protein and pyrophosphate-releasing xanthosine/ inosine triphosphatase. HAM1 protects the cell against mutagenesis by the base analog 6-N-hydroxylaminopurine (HAP) in E. Coli and S. cerevisiae. A...; Region: HAM1; cd00515
553482008637	active site
553482008638	dimerization interface [polypeptide binding]; other site
553482008639	HMMPfam hit to PF01725, Ham1 family, score 3.5e-66
553482008640	PS00017 ATP/GTP-binding site motif A (P-loop).
553482008641	glutamate racemase; Provisional; Region: PRK00865
553482008642	HMMPfam hit to PF01177, Asp/Glu/Hydantoin racemase, score 1.5e-100
553482008643	PS00924 Aspartate and glutamate racemases signature 2.
553482008644	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482008645	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3763
553482008646	HMMPfam hit to PF03672, Uncharacterised protein family (UPF0154), score 5.1e-19
553482008647	1 transmembrane helix predicted for SEQ1869 by TMHMM2.0 at aa 4-26
553482008648	Integral membrane protein, interacts with FtsH [General function prediction only]; Region: COG0670
553482008649	Bacterial BAX inhibitor (BI)-1/YccA-like proteins; Region: BI-1-like_bacterial; cd10432
553482008650	HMMPfam hit to PF01027, Uncharacterised protein family UPF0005, score 4e-21
553482008651	7 transmembrane helices predicted for SEQ1870 by TMHMM2.0 at aa 21-43, 58-76, 83-105, 110-129, 142-159, 163-182 and 202-224
553482008652	Predicted HD superfamily hydrolase [General function prediction only]; Region: COG1418
553482008653	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cl17215
553482008654	Zn2+ binding site [ion binding]; other site
553482008655	Mg2+ binding site [ion binding]; other site
553482008656	rRNA methylase, putative, group 3; Region: rRNA_methyl_3; TIGR00186
553482008657	RNA 2'-O ribose methyltransferase substrate binding; Region: SpoU_sub_bind; smart00967
553482008658	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
553482008659	HMMPfam hit to PF00588, SpoU rRNA Methylase family, score 3e-49
553482008660	HMMPfam hit to PF08032, RNA 2'-O ribose methyltransferase subs, score 1.6e-15
553482008661	putative transposase OrfB; Reviewed; Region: PHA02517
553482008662	HTH-like domain; Region: HTH_21; pfam13276
553482008663	Integrase core domain; Region: rve; pfam00665
553482008664	Integrase core domain; Region: rve_2; pfam13333
553482008665	HMMPfam hit to PF00665, Integrase core domain, score 8.8e-38
553482008666	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
553482008667	Helix-turn-helix domain; Region: HTH_28; pfam13518
553482008668	HMMPfam hit to PF01527, Transposase, score 0.00062
553482008669	HMMPfam hit to PF02178, no description, score 0.21
553482008670	Predicted helix-turn-helix motif with score 1140.000, SD 3.07 at aa 19-40, sequence KSIKCLSEKFSIAESDLKYMIR
553482008671	acylphosphatase; Provisional; Region: PRK14434
553482008672	HMMPfam hit to PF00708, Acylphosphatase, score 2.5e-07
553482008673	PS00150 Acylphosphatase signature 1.
553482008674	OxaA-like protein precursor; Provisional; Region: PRK02463
553482008675	membrane protein insertase, YidC/Oxa1 family, C-terminal domain; Region: yidC_oxa1_cterm; TIGR03592
553482008676	5 transmembrane helices predicted for SEQ1878 by TMHMM2.0 at aa 7-26, 58-80, 135-157, 177-199 and 220-242
553482008677	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482008678	HMMPfam hit to PF02096, 60Kd inner membrane protein, score 1.1e-36
553482008679	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482008680	transcription elongation factor GreA; Reviewed; Region: greA; PRK00226
553482008681	Transcription elongation factor, N-terminal; Region: GreA_GreB_N; pfam03449
553482008682	Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272
553482008683	HMMPfam hit to PF01272, Prokaryotic transcription elongation fact, score 2.2e-16
553482008684	PS00830 Prokaryotic transcription elongation factors signature 2.
553482008685	HMMPfam hit to PF03449, Prokaryotic transcription elongation fact, score 3e-24
553482008686	Aminodeoxychorismate lyase [Coenzyme transport and metabolism]; Region: COG1559
553482008687	proteins similar to Escherichia coli yceG; Region: yceG_like; cd08010
553482008688	dimerization interface [polypeptide binding]; other site
553482008689	HMMPfam hit to PF02618, Aminodeoxychorismate lyase, score 8.4e-138
553482008690	PS00017 ATP/GTP-binding site motif A (P-loop).
553482008691	1 transmembrane helix predicted for SEQ1880 by TMHMM2.0 at aa 157-179
553482008692	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
553482008693	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
553482008694	Coenzyme A binding pocket [chemical binding]; other site
553482008695	HMMPfam hit to PF00583, Acetyltransferase (GNAT) family, score 3.7e-10
553482008696	UDP-N-acetylmuramate--L-alanine ligase; Provisional; Region: murC; PRK00421
553482008697	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
553482008698	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
553482008699	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
553482008700	HMMPfam hit to PF02875, Mur ligase family, glutamate ligase doma, score 9.7e-20
553482008701	HMMPfam hit to PF08245, Mur ligase middle domain, score 5.8e-27
553482008702	HMMPfam hit to PF01225, Mur ligase family, catalytic domain, score 3.5e-37
553482008703	SWIM zinc finger; Region: SWIM; pfam04434
553482008704	Bacterial SNF2 helicase associated; Region: SNF2_assoc; pfam08455
553482008705	SNF2 family N-terminal domain; Region: SNF2_N; pfam00176
553482008706	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
553482008707	ATP binding site [chemical binding]; other site
553482008708	putative Mg++ binding site [ion binding]; other site
553482008709	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
553482008710	nucleotide binding region [chemical binding]; other site
553482008711	ATP-binding site [chemical binding]; other site
553482008712	HMMPfam hit to PF00271, Helicase conserved C-terminal domain, score 2.3e-25
553482008713	PS00697 ATP-dependent DNA ligase AMP-binding site.
553482008714	HMMPfam hit to PF00176, SNF2 family N-terminal domain, score 3.2e-60
553482008715	HMMPfam hit to PF08455, Bacterial SNF2 helicase associated, score 4.5e-128
553482008716	HMMPfam hit to PF04434, SWIM zinc finger, score 4.5e-07
553482008717	GTP-binding protein Der; Reviewed; Region: PRK00093
553482008718	EngA1 GTPase contains the first domain of EngA; Region: EngA1; cd01894
553482008719	G1 box; other site
553482008720	GTP/Mg2+ binding site [chemical binding]; other site
553482008721	Switch I region; other site
553482008722	G2 box; other site
553482008723	Switch II region; other site
553482008724	G3 box; other site
553482008725	G4 box; other site
553482008726	G5 box; other site
553482008727	EngA2 GTPase contains the second domain of EngA; Region: EngA2; cd01895
553482008728	G1 box; other site
553482008729	GTP/Mg2+ binding site [chemical binding]; other site
553482008730	Switch I region; other site
553482008731	G2 box; other site
553482008732	G3 box; other site
553482008733	Switch II region; other site
553482008734	G4 box; other site
553482008735	G5 box; other site
553482008736	HMMPfam hit to PF01926, GTPase of unknown function, score 4.1e-41
553482008737	PS00017 ATP/GTP-binding site motif A (P-loop).
553482008738	HMMPfam hit to PF01926, GTPase of unknown function, score 8.5e-46
553482008739	PS00017 ATP/GTP-binding site motif A (P-loop).
553482008740	primosomal protein DnaI; Reviewed; Region: PRK08939
553482008741	Primosomal protein DnaI N-terminus; Region: DnaI_N; pfam07319
553482008742	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
553482008743	Walker A motif; other site
553482008744	ATP binding site [chemical binding]; other site
553482008745	Walker B motif; other site
553482008746	PS00017 ATP/GTP-binding site motif A (P-loop).
553482008747	HMMPfam hit to PF07319, Primosomal protein DnaI N-terminus, score 2.7e-45
553482008748	Replication initiation/membrane attachment protein [DNA replication, recombination, and repair]; Region: DnaB; COG3611
553482008749	HMMPfam hit to PF07261, Replication initiation and membrane attachme, score 6.7e-07
553482008750	Predicted helix-turn-helix motif with score 979.000, SD 2.52 at aa 359-380, sequence TSQEEQAKLEQFKQAALKRLEN
553482008751	transcriptional regulator NrdR; Validated; Region: nrdR; PRK00464
553482008752	ATP cone domain; Region: ATP-cone; pfam03477
553482008753	HMMPfam hit to PF03477, ATP cone domain, score 2.2e-33
553482008754	PS00190 Cytochrome c family heme-binding site signature.
553482008755	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
553482008756	HAMP domain; Region: HAMP; pfam00672
553482008757	dimerization interface [polypeptide binding]; other site
553482008758	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
553482008759	dimer interface [polypeptide binding]; other site
553482008760	phosphorylation site [posttranslational modification]
553482008761	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
553482008762	ATP binding site [chemical binding]; other site
553482008763	Mg2+ binding site [ion binding]; other site
553482008764	G-X-G motif; other site
553482008765	HMMPfam hit to PF02518, Histidine kinase-, DNA gyrase B-, and HSP90, score 5.8e-31
553482008766	HMMPfam hit to PF00512, His Kinase A (phosphoacceptor) domain, score 7.8e-17
553482008767	HMMPfam hit to PF00672, HAMP domain, score 1.1e-10
553482008768	2 transmembrane helices predicted for SEQ1889 by TMHMM2.0 at aa 20-42 and 187-209
553482008769	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
553482008770	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
553482008771	active site
553482008772	phosphorylation site [posttranslational modification]
553482008773	intermolecular recognition site; other site
553482008774	dimerization interface [polypeptide binding]; other site
553482008775	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
553482008776	DNA binding site [nucleotide binding]
553482008777	HMMPfam hit to PF00486, Transcriptional regulatory protein, C te, score 1.6e-19
553482008778	HMMPfam hit to PF00072, Response regulator receiver domain, score 6.6e-40
553482008779	PS00217 Sugar transport proteins signature 2.
553482008780	Predicted metal-binding, possibly nucleic acid-binding protein [General function prediction only]; Region: COG1399
553482008781	HMMPfam hit to PF02620, Uncharacterized ACR, COG1399, score 5.4e-43
553482008782	heat shock protein HtpX; Provisional; Region: PRK04897
553482008783	HMMPfam hit to PF01435, Peptidase family M48, score 5.7e-20
553482008784	4 transmembrane helices predicted for SEQ1892 by TMHMM2.0 at aa 13-35, 45-67, 157-179 and 194-216
553482008785	Uncharacterized conserved protein [Function unknown]; Region: LemA; COG1704
553482008786	HMMPfam hit to PF04011, LemA family, score 6.5e-108
553482008787	1 transmembrane helix predicted for SEQ1893 by TMHMM2.0 at aa 4-26
553482008788	Predicted S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division [Cell envelope biogenesis, outer membrane]; Region: GidB; COG0357
553482008789	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
553482008790	S-adenosylmethionine binding site [chemical binding]; other site
553482008791	HMMPfam hit to PF02527, Glucose inhibited division protein, score 9.4e-58
553482008792	Trk-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: TrkG; COG0168
553482008793	potassium uptake protein, TrkH family; Region: 2a38; TIGR00933
553482008794	9 transmembrane helices predicted for SEQ1895 by TMHMM2.0 at aa 15-37, 49-67, 77-99, 128-150, 160-182, 195-217, 242-261, 365-384 and 419-441
553482008795	HMMPfam hit to PF02386, Cation transport protein, score 3.9e-59
553482008796	K+ transport systems, NAD-binding component [Inorganic ion transport and metabolism]; Region: TrkA; COG0569
553482008797	TrkA-N domain; Region: TrkA_N; pfam02254
553482008798	HMMPfam hit to PF02254, TrkA-N domain, score 9.2e-38
553482008799	serine/threonine transporter SstT; Provisional; Region: PRK13628
553482008800	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
553482008801	HMMPfam hit to PF00375, Sodium:dicarboxylate symporter family, score 2.9e-112
553482008802	9 transmembrane helices predicted for SEQ1897 by TMHMM2.0 at aa 17-39, 43-65, 78-100, 136-158, 178-200, 210-232, 287-309, 324-346 and 353-375
553482008803	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482008804	Branched-chain amino acid transport protein; Region: Branch_AA_trans; pfam05525
553482008805	HMMPfam hit to PF05525, Branched-chain amino acid transport p, score 4.7e-206
553482008806	12 transmembrane helices predicted for SEQ1898 by TMHMM2.0 at aa 7-29, 39-61, 78-97, 117-136, 148-170, 192-214, 234-256, 296-318, 331-353, 357-376, 385-407 and 427-449
553482008807	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482008808	ABC-type metal ion transport system, permease component [Inorganic ion transport and metabolism]; Region: AbcD; COG2011
553482008809	HMMPfam hit to PF00528, Binding-protein-dependent transport syst, score 6e-13
553482008810	4 transmembrane helices predicted for SEQ1899 by TMHMM2.0 at aa 32-54, 75-97, 166-188 and 201-220
553482008811	ABC-type metal ion transport system, ATPase component [Inorganic ion transport and metabolism]; Region: AbcC; COG1135
553482008812	ATP-binding cassette domain of methionine transporter; Region: ABC_MetN_methionine_transporter; cd03258
553482008813	Walker A/P-loop; other site
553482008814	ATP binding site [chemical binding]; other site
553482008815	Q-loop/lid; other site
553482008816	ABC transporter signature motif; other site
553482008817	Walker B; other site
553482008818	D-loop; other site
553482008819	H-loop/switch region; other site
553482008820	NIL domain; Region: NIL; pfam09383
553482008821	HMMPfam hit to PF00005, ABC transporter, score 2.3e-67
553482008822	PS00211 ABC transporters family signature.
553482008823	PS00017 ATP/GTP-binding site motif A (P-loop).
553482008824	hypothetical protein; Provisional; Region: PRK06446
553482008825	Uncharacterized M20 Dipeptidases; Region: M20_dipept_like_4; cd05681
553482008826	metal binding site [ion binding]; metal-binding site
553482008827	dimer interface [polypeptide binding]; other site
553482008828	HMMPfam hit to PF01546, Peptidase family M20/M25/M40, score 7.2e-27
553482008829	Predicted helix-turn-helix motif with score 1057.000, SD 2.79 at aa 363-384, sequence YTLGEMSYRSDLSSSAISQLIA
553482008830	HMMPfam hit to PF07687, Peptidase dimerisation domain, score 1.2e-08
553482008831	ABC-type metal ion transport system, periplasmic component/surface antigen [Inorganic ion transport and metabolism]; Region: NlpA; COG1464
553482008832	NLPA lipoprotein; Region: Lipoprotein_9; pfam03180
553482008833	HMMPfam hit to PF03180, NLPA lipoprotein, score 2.5e-112
553482008834	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482008835	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
553482008836	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
553482008837	substrate binding pocket [chemical binding]; other site
553482008838	membrane-bound complex binding site; other site
553482008839	hinge residues; other site
553482008840	HMMPfam hit to PF00497, Bacterial extracellular solute-binding prot, score 1.2e-75
553482008841	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482008842	hypothetical protein; Provisional; Region: PRK12378
553482008843	HMMPfam hit to PF01709, Domain of unknown function DUF28, score 4.2e-125
553482008844	Predicted transcriptional regulators [Transcription]; Region: SoxR; COG0789
553482008845	Helix-Turn-Helix DNA binding domain of the transcription regulators TipAL, Mta, and SkgA; Region: HTH_TipAL-Mta; cd01106
553482008846	DNA binding residues [nucleotide binding]
553482008847	dimer interface [polypeptide binding]; other site
553482008848	TipAS antibiotic-recognition domain; Region: TipAS; pfam07739
553482008849	HMMPfam hit to PF07739, TipAS antibiotic-recognition domain, score 4.6e-35
553482008850	HMMPfam hit to PF00376, MerR family regulatory protein, score 5e-06
553482008851	hypothetical protein; Provisional; Region: PRK13670
553482008852	HIGH Nucleotidyl Transferase; Region: HIGH_NTase1; cl17673
553482008853	HMMPfam hit to PF05636, Protein of unknown function (DUF795), score 4.6e-178
553482008854	SAM-dependent methyltransferases [Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only]; Region: SmtA; COG0500
553482008855	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
553482008856	S-adenosylmethionine binding site [chemical binding]; other site
553482008857	HMMPfam hit to PF01209, ubiE/COQ5 methyltransferase family, score 1.2e-05
553482008858	HMMPfam hit to PF08241, Methyltransferase domain, score 2.3e-21
553482008859	HMMPfam hit to PF08242, Methyltransferase domain, score 4.6e-18
553482008860	Uncharacterized homolog of plant Iojap protein [Function unknown]; Region: COG0799
553482008861	HMMPfam hit to PF02410, Domain of unknown function DUF143, score 1.4e-43
553482008862	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
553482008863	Zn2+ binding site [ion binding]; other site
553482008864	Mg2+ binding site [ion binding]; other site
553482008865	HMMPfam hit to PF01966, HD domain, score 2.5e-11
553482008866	nicotinic acid mononucleotide adenylyltransferase; Provisional; Region: nadD; PRK00071
553482008867	Nicotinamide/nicotinate mononucleotide adenylyltransferase; Region: NMNAT; cd02165
553482008868	active site
553482008869	(T/H)XGH motif; other site
553482008870	HMMPfam hit to PF01467, Cytidylyltransferase, score 3.9e-61
553482008871	Predicted RNA-binding protein containing KH domain, possibly ribosomal protein [Translation, ribosomal structure and biogenesis]; Region: COG1534
553482008872	HMMPfam hit to PF01985, CRS1 / YhbY domain, score 4.6e-34
553482008873	GTPase YqeH; Provisional; Region: PRK13796
553482008874	Circularly permuted YqeH GTPase; Region: YqeH; cd01855
553482008875	GTP/Mg2+ binding site [chemical binding]; other site
553482008876	G4 box; other site
553482008877	G5 box; other site
553482008878	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cl17170
553482008879	G1 box; other site
553482008880	G1 box; other site
553482008881	GTP/Mg2+ binding site [chemical binding]; other site
553482008882	G2 box; other site
553482008883	Switch I region; other site
553482008884	G2 box; other site
553482008885	Switch I region; other site
553482008886	G3 box; other site
553482008887	G3 box; other site
553482008888	Switch II region; other site
553482008889	Switch II region; other site
553482008890	G4 box; other site
553482008891	HMMPfam hit to PF01926, GTPase of unknown function, score 7.6e-11
553482008892	PS00017 ATP/GTP-binding site motif A (P-loop).
553482008893	Predicted hydrolase of the HAD superfamily [General function prediction only]; Region: COG2179
553482008894	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
553482008895	active site
553482008896	motif I; other site
553482008897	motif II; other site
553482008898	PS00678 Trp-Asp (WD) repeats signature.
553482008899	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppF; COG1124
553482008900	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
553482008901	Walker A/P-loop; other site
553482008902	ATP binding site [chemical binding]; other site
553482008903	Q-loop/lid; other site
553482008904	ABC transporter signature motif; other site
553482008905	Walker B; other site
553482008906	D-loop; other site
553482008907	H-loop/switch region; other site
553482008908	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
553482008909	HMMPfam hit to PF08352, Oligopeptide/dipeptide transporter, C-termi, score 1.6e-07
553482008910	HMMPfam hit to PF00005, ABC transporter, score 7.4e-53
553482008911	PS00211 ABC transporters family signature.
553482008912	PS00017 ATP/GTP-binding site motif A (P-loop).
553482008913	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppD; COG0444
553482008914	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
553482008915	Walker A/P-loop; other site
553482008916	ATP binding site [chemical binding]; other site
553482008917	Q-loop/lid; other site
553482008918	ABC transporter signature motif; other site
553482008919	Walker B; other site
553482008920	D-loop; other site
553482008921	H-loop/switch region; other site
553482008922	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
553482008923	HMMPfam hit to PF08352, Oligopeptide/dipeptide transporter, C-termi, score 8.5e-23
553482008924	HMMPfam hit to PF00005, ABC transporter, score 5e-69
553482008925	PS00211 ABC transporters family signature.
553482008926	PS00017 ATP/GTP-binding site motif A (P-loop).
553482008927	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppC; COG1173
553482008928	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
553482008929	dimer interface [polypeptide binding]; other site
553482008930	conserved gate region; other site
553482008931	putative PBP binding loops; other site
553482008932	ABC-ATPase subunit interface; other site
553482008933	HMMPfam hit to PF00528, Binding-protein-dependent transport syst, score 5.6e-37
553482008934	6 transmembrane helices predicted for SEQ1917 by TMHMM2.0 at aa 42-64, 110-132, 145-167, 171-193, 214-236 and 274-296
553482008935	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
553482008936	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
553482008937	dimer interface [polypeptide binding]; other site
553482008938	conserved gate region; other site
553482008939	putative PBP binding loops; other site
553482008940	ABC-ATPase subunit interface; other site
553482008941	HMMPfam hit to PF00528, Binding-protein-dependent transport syst, score 6.5e-52
553482008942	6 transmembrane helices predicted for SEQ1918 by TMHMM2.0 at aa 9-31, 287-309, 321-343, 358-380, 419-441 and 461-483
553482008943	ABC-type oligopeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: OppA; COG4166
553482008944	The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold; Region: PBP2_OppA; cd08504
553482008945	peptide binding site [polypeptide binding]; other site
553482008946	HMMPfam hit to PF00496, Bacterial extracellular solute-binding prot, score 2e-48
553482008947	PS01040 Bacterial extracellular solute-binding proteins, family 5 signature.
553482008948	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482008949	D-alanyl-D-alanine carboxypeptidase [Cell envelope biogenesis, outer membrane]; Region: DacC; COG1686
553482008950	Beta-lactamase enzyme family; Region: Beta-lactamase2; cl17872
553482008951	Penicillin-binding protein 5, C-terminal domain; Region: PBP5_C; smart00936
553482008952	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482008953	HMMPfam hit to PF00768, D-alanyl-D-alanine carboxypeptidase, score 2.1e-106
553482008954	PS00307 Legume lectins beta-chain signature.
553482008955	HMMPfam hit to PF07943, Penicillin-binding protein 5, C-termina, score 1.9e-09
553482008956	D-alanyl-D-alanine carboxypeptidase [Cell envelope biogenesis, outer membrane]; Region: DacC; COG1686
553482008957	Penicillin-binding protein 5, C-terminal domain; Region: PBP5_C; smart00936
553482008958	HMMPfam hit to PF00768, D-alanyl-D-alanine carboxypeptidase, score 1.3e-96
553482008959	D-alanyl-D-alanine carboxypeptidase; Region: Peptidase_S11; pfam00768
553482008960	Beta-lactamase enzyme family; Region: Beta-lactamase2; cl17872
553482008961	2 transmembrane helices predicted for SEQ1922 by TMHMM2.0 at aa 5-23 and 368-390
553482008962	HMMPfam hit to PF00768, D-alanyl-D-alanine carboxypeptidase, score 6e-37
553482008963	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
553482008964	Helix-turn-helix domain; Region: HTH_28; pfam13518
553482008965	Predicted helix-turn-helix motif with score 1140.000, SD 3.07 at aa 19-40, sequence KSIKCLSEKFSIAESDLKYMIR
553482008966	HMMPfam hit to PF01527, Transposase, score 0.00062
553482008967	HMMPfam hit to PF02178, no description, score 0.21
553482008969	cysteine desulfurase activator complex subunit SufB; Provisional; Region: PRK11814; cl03223
553482008970	FeS assembly protein SufB; Region: sufB; TIGR01980
553482008971	HMMPfam hit to PF01458, Uncharacterized protein family (UPF0051), score 8.1e-116
553482008972	NifU homolog involved in Fe-S cluster formation [Energy production and conversion]; Region: IscU; COG0822
553482008973	Iron-sulfur cluster scaffold-like proteins; Region: IscU_like; cd06664
553482008974	trimerization site [polypeptide binding]; other site
553482008975	active site
553482008976	HMMPfam hit to PF01592, NifU-like N terminal domain, score 3.4e-28
553482008977	Selenocysteine lyase/Cysteine desulfurase [Posttranslational modification, protein turnover, chaperones]; Region: csdA; COG0520
553482008978	Cysteine desulfurase (SufS)-like. This family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to cysteine desulfurase (SufS) and selenocysteine lyase. SufS...; Region: SufS_like; cd06453
553482008979	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
553482008980	catalytic residue [active]
553482008981	HMMPfam hit to PF00266, Aminotransferase class-V, score 6.2e-216
553482008982	HMMPfam hit to PF01212, Beta-eliminating lyase, score 0.0012
553482008983	PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site.
553482008984	Cysteine desulfurase activator SufB [Posttranslational modification, protein turnover, chaperones]; Region: SufB; COG0719
553482008985	FeS assembly protein SufD; Region: sufD; TIGR01981
553482008986	HMMPfam hit to PF01458, Uncharacterized protein family (UPF0051), score 4.4e-49
553482008987	Cysteine desulfurase activator ATPase [Posttranslational modification, protein turnover, chaperones]; Region: sufC; COG0396
553482008988	ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Region: ABC_FeS_Assembly; cd03217
553482008989	Walker A/P-loop; other site
553482008990	ATP binding site [chemical binding]; other site
553482008991	Q-loop/lid; other site
553482008992	ABC transporter signature motif; other site
553482008993	Walker B; other site
553482008994	D-loop; other site
553482008995	H-loop/switch region; other site
553482008996	HMMPfam hit to PF00005, ABC transporter, score 5.5e-31
553482008997	PS00211 ABC transporters family signature.
553482008998	PS00017 ATP/GTP-binding site motif A (P-loop).
553482008999	UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase [Cell envelope biogenesis, outer membrane]; Region: Rfe; COG0472
553482009000	This subfamily contains Escherichia coli WecA, Bacillus subtilis TagO and related proteins. WecA is an UDP-N-acetylglucosamine (GlcNAc):undecaprenyl-phosphate (Und-P) GlcNAc-1-phosphate transferase that catalyzes the formation of a phosphodiester bond...; Region: GT_WecA_like; cd06853
553482009001	Mg++ binding site [ion binding]; other site
553482009002	putative catalytic motif [active]
553482009003	substrate binding site [chemical binding]; other site
553482009004	11 transmembrane helices predicted for SEQ1931 by TMHMM2.0 at aa 10-31, 52-71, 81-103, 110-129, 144-163, 175-197, 201-218, 225-244, 254-276, 306-328 and 333-355
553482009005	HMMPfam hit to PF00953, Glycosyl transferase family, score 6e-41
553482009006	adaptor protein; Provisional; Region: PRK02315
553482009007	HMMPfam hit to PF05389, Negative regulator of genetic competence (Me, score 1.2e-113
553482009008	Predicted helix-turn-helix motif with score 1036.000, SD 2.72 at aa 84-105, sequence LNFEDLADLGDISQMTPEDFFR
553482009009	undecaprenyl pyrophosphate phosphatase; Reviewed; Region: PRK00281
553482009010	8 transmembrane helices predicted for SEQ1933 by TMHMM2.0 at aa 2-24, 44-66, 87-105, 115-133, 154-176, 186-208, 221-243 and 258-275
553482009011	HMMPfam hit to PF02673, Bacitracin resistance protein BacA, score 2.9e-119
553482009012	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
553482009013	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
553482009014	substrate binding pocket [chemical binding]; other site
553482009015	membrane-bound complex binding site; other site
553482009016	hinge residues; other site
553482009017	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
553482009018	dimer interface [polypeptide binding]; other site
553482009019	conserved gate region; other site
553482009020	putative PBP binding loops; other site
553482009021	ABC-ATPase subunit interface; other site
553482009022	4 transmembrane helices predicted for SEQ1934 by TMHMM2.0 at aa 5-24, 298-320, 360-382 and 473-495
553482009023	HMMPfam hit to PF00497, Bacterial extracellular solute-binding p, score 1.1e-35
553482009024	HMMPfam hit to PF00528, Binding-protein-dependent transport syst, score 1.1e-23
553482009025	PS00402 Binding-protein-dependent transport systems inner membrane comp. sign.
553482009026	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
553482009027	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
553482009028	Walker A/P-loop; other site
553482009029	ATP binding site [chemical binding]; other site
553482009030	Q-loop/lid; other site
553482009031	ABC transporter signature motif; other site
553482009032	Walker B; other site
553482009033	D-loop; other site
553482009034	H-loop/switch region; other site
553482009035	HMMPfam hit to PF00005, ABC transporter, score 2.2e-62
553482009036	PS00017 ATP/GTP-binding site motif A (P-loop).
553482009037	PS00211 ABC transporters family signature.
553482009038	Membrane protease subunits, stomatin/prohibitin homologs [Posttranslational modification, protein turnover, chaperones]; Region: HflC; COG0330
553482009039	A subgroup of the band 7 domain of flotillin (reggie) like proteins. This subgroup contains proteins similar to stomatin, prohibitin, flotillin, HlfK/C and podicin.  Many of these band 7 domain-containing proteins are lipid raft-associated.  Individual...; Region: Band_7_4; cd03407
553482009040	HMMPfam hit to PF01145, SPFH domain / Band, score 4.3e-41
553482009041	1 transmembrane helix predicted for SEQ1937 by TMHMM2.0 at aa 4-26
553482009042	DAK2 domain fusion protein YloV; Region: YloV; TIGR03599
553482009043	DAK2 domain; Region: Dak2; pfam02734
553482009044	HMMPfam hit to PF02734, DAK2 domain, score 1.1e-75
553482009045	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1302
553482009046	HMMPfam hit to PF03780, Protein of unknown function (DUF322), score 1.9e-53
553482009047	50S ribosomal protein L28; Reviewed; Region: rpmB; PRK00359
553482009048	HMMPfam hit to PF00830, Ribosomal L28 family, score 3.1e-24
553482009049	1 transmembrane helix predicted for SEQ1941 by TMHMM2.0 at aa 15-34
553482009050	PS00099 Thiolases active site.
553482009051	gene remnant. Similar to an internal region of Streptococcus thermophilus integrase Int UniProt:Q9L4G5 (EMBL:AJ243106 (448 aa) fasta scores: E()=0.032, 36.957% id in 46 aa
553482009052	fructose-bisphosphate aldolase; Provisional; Region: PRK09197
553482009053	Tagatose-1,6-bisphosphate (TBP) aldolase and related Type B Class II aldolases. TBP aldolase is a tetrameric class II aldolase that catalyzes the reversible condensation of dihydroxyacetone phosphate with glyceraldehyde 3-phsophate to produce tagatose 1; Region: TBP_aldolase_IIB; cd00947
553482009054	intersubunit interface [polypeptide binding]; other site
553482009055	active site
553482009056	zinc binding site [ion binding]; other site
553482009057	Na+ binding site [ion binding]; other site
553482009058	PS00806 Fructose-bisphosphate aldolase class-II signature 2.
553482009059	PS00602 Fructose-bisphosphate aldolase class-II signature 1.
553482009060	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
553482009061	Alpha/beta hydrolase family; Region: Abhydrolase_5; pfam12695
553482009062	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
553482009063	1 transmembrane helix predicted for SEQ1944 by TMHMM2.0 at aa 9-31
553482009064	CTP synthetase; Validated; Region: pyrG; PRK05380
553482009065	CTP synthetase (CTPs) is a two-domain protein, which consists of an N-terminal synthetase domain and C-terminal glutaminase domain. The enzymes hydrolyze the amide bond of glutamine to ammonia and glutamate at the glutaminase domains and transfer nascent...; Region: CTGs; cd03113
553482009066	Catalytic site [active]
553482009067	active site
553482009068	UTP binding site [chemical binding]; other site
553482009069	Type 1 glutamine amidotransferase (GATase1) domain found in Cytidine Triphosphate Synthetase; Region: GATase1_CTP_Synthase; cd01746
553482009070	active site
553482009071	putative oxyanion hole; other site
553482009072	catalytic triad [active]
553482009073	HMMPfam hit to PF00117, Glutamine amidotransferase class-I, score 9.1e-69
553482009074	HMMPfam hit to PF06418, CTP synthase N-terminus, score 6.4e-216
553482009075	DNA-directed RNA polymerase delta subunit; Region: RNA_pol_delta; pfam05066
553482009076	HMMPfam hit to PF05066, DNA-directed RNA polymerase delta subun, score 1.6e-98
553482009077	trigger factor; Provisional; Region: tig; PRK01490
553482009078	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
553482009079	Bacterial trigger factor protein (TF) C-terminus; Region: Trigger_C; pfam05698
553482009080	HMMPfam hit to PF05698, Bacterial trigger factor protein (TF) C-ter, score 1.1e-67
553482009081	Predicted helix-turn-helix motif with score 987.000, SD 2.55 at aa 382-403, sequence KEINDLAAEYSMPVEQVRSLLS
553482009082	HMMPfam hit to PF00254, FKBP-type peptidyl-prolyl cis-trans isomera, score 1.5e-27
553482009083	HMMPfam hit to PF05697, Bacterial trigger factor protein (TF), score 5.1e-58
553482009084	Glycosidases [Carbohydrate transport and metabolism]; Region: AmyA; COG0366
553482009085	Alpha amylase catalytic domain found in bacterial Alpha-amylases (also called 1,4-alpha-D-glucan-4-glucanohydrolase); Region: AmyAc_bac1_AmyA; cd11315
553482009086	active site
553482009087	Ca binding site [ion binding]; other site
553482009088	catalytic site [active]
553482009089	Alpha amylase, C-terminal all-beta domain; Region: Alpha-amylase_C; cl02706
553482009090	HMMPfam hit to PF00128, Alpha amylase, catalytic domain, score 1.3e-48
553482009091	Small-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscS; COG0668
553482009092	Mechanosensitive ion channel; Region: MS_channel; pfam00924
553482009093	3 transmembrane helices predicted for SEQ1950 by TMHMM2.0 at aa 15-37, 72-94 and 104-126
553482009094	HMMPfam hit to PF00924, Mechanosensitive ion channel, score 2.9e-53
553482009095	hypothetical protein; Provisional; Region: PRK13690
553482009096	ECF-type riboflavin transporter, S component; Region: ECF-ribofla_trS; pfam07155
553482009097	4 transmembrane helices predicted for SEQ1952 by TMHMM2.0 at aa 7-26, 53-75, 95-117 and 130-147
553482009098	4-amino-5-hydroxymethyl-2-methyl-pyrimidine phosphate kinase (HMPP-kinase) catalyzes two consecutive phosphorylation steps in the thiamine phosphate biosynthesis pathway, leading to the synthesis of vitamin B1. The first step is the phosphorylation of...; Region: HMPP_kinase; cd01169
553482009099	dimer interface [polypeptide binding]; other site
553482009100	substrate binding site [chemical binding]; other site
553482009101	ATP binding site [chemical binding]; other site
553482009102	HMMPfam hit to PF08543, Phosphomethylpyrimidine kinase, score 5.4e-66
553482009103	HMMPfam hit to PF01256, Carbohydrate kinase, score 0.00022
553482009104	tRNA pseudouridine synthase A; Validated; Region: truA; PRK00021
553482009105	Eukaryotic and bacterial pseudouridine synthases similar to E.  coli TruA; Region: PseudoU_synth_EcTruA; cd02570
553482009106	dimerization interface 3.5A [polypeptide binding]; other site
553482009107	active site
553482009108	HMMPfam hit to PF01416, tRNA pseudouridine synthase, score 1.8e-31
553482009109	HMMPfam hit to PF01416, tRNA pseudouridine synthase, score 5.2e-38
553482009110	aspartate kinase; Reviewed; Region: PRK09034
553482009111	AAK_AKiii-YclM-BS: Amino Acid Kinase Superfamily (AAK), AKiii-YclM-BS; this CD includes the N-terminal catalytic aspartokinase (AK) domain of the lysine plus threonine-sensitive aspartokinase isoenzyme AKIII, a monofunctional class enzyme found in...; Region: AAK_AKiii-YclM-BS; cd04245
553482009112	putative catalytic residues [active]
553482009113	putative nucleotide binding site [chemical binding]; other site
553482009114	putative aspartate binding site [chemical binding]; other site
553482009115	ACT domains located C-terminal to the catalytic domain of the lysine plus threonine-sensitive aspartokinase isoenzyme AKIII; Region: ACT_AKiii-YclM-BS_1; cd04911
553482009116	allosteric regulatory residue; other site
553482009117	ACT domains located C-terminal to the catalytic domain of the lysine plus threonine-sensitive aspartokinase isoenzyme AKIII; Region: ACT_AKiii-YclM-BS_2; cd04916
553482009118	HMMPfam hit to PF00696, Amino acid kinase family, score 3.3e-33
553482009119	PS00324 Aspartokinase signature.
553482009120	HMMPfam hit to PF01842, ACT domain, score 0.75
553482009121	HMMPfam hit to PF01842, ACT domain, score 2.4e-08
553482009122	streptococcal histidine triad protein; Region: strep_his_triad; TIGR01363
553482009123	Streptococcal histidine triad protein; Region: Strep_his_triad; pfam04270
553482009124	Streptococcal histidine triad protein; Region: Strep_his_triad; pfam04270
553482009125	streptococcal histidine triad protein; Region: strep_his_triad; TIGR01363
553482009126	HMMPfam hit to PF04270, Streptococcal histidine triad protein, score 0.034
553482009127	HMMPfam hit to PF04270, Streptococcal histidine triad protein, score 0.0072
553482009128	HMMPfam hit to PF04270, Streptococcal histidine triad protein, score 6.3e-10
553482009129	HMMPfam hit to PF04270, Streptococcal histidine triad protein, score 7.2e-35
553482009130	1 transmembrane helix predicted for SEQ1957 by TMHMM2.0 at aa 5-27
553482009131	ABC-type metal ion transport system, periplasmic component/surface adhesin [Inorganic ion transport and metabolism]; Region: LraI; COG0803
553482009132	Helical backbone metal receptor (TroA-like domain). These proteins have been shown to function in the ABC transport of ferric siderophores and metal ions such as Mn2+, Fe3+, Cu2+ and/or Zn2+.  Their ligand binding site is formed in the interface between...; Region: TroA-like; cl00262
553482009133	intersubunit interface [polypeptide binding]; other site
553482009134	HMMPfam hit to PF01297, Periplasmic solute binding protein family, score 4.9e-115
553482009135	PS00339 Aminoacyl-transfer RNA synthetases class-II signature 2.
553482009136	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482009137	1 transmembrane helix predicted for SEQ1959 by TMHMM2.0 at aa 487-509
553482009138	PS00017 ATP/GTP-binding site motif A (P-loop).
553482009139	PS00017 ATP/GTP-binding site motif A (P-loop).
553482009140	Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase [Lipid metabolism / General function prediction only]; Region: LCB5; COG1597
553482009141	Diacylglycerol kinase catalytic domain; Region: DAGK_cat; pfam00781
553482009142	HMMPfam hit to PF00781, Diacylglycerol kinase catalytic domain (pres, score 1.8e-34
553482009143	DNA-binding transcriptional repressor EbgR; Provisional; Region: PRK10339
553482009144	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
553482009145	DNA binding site [nucleotide binding]
553482009146	domain linker motif; other site
553482009147	Ligand-binding domain of DNA transcription repressor GalR which is one of two regulatory proteins involved in galactose transport and metabolism; Region: PBP1_GalR; cd01544
553482009148	putative dimerization interface [polypeptide binding]; other site
553482009149	putative ligand binding site [chemical binding]; other site
553482009150	HMMPfam hit to PF00356, Bacterial regulatory proteins, lacI family, score 3.7e-10
553482009151	Predicted helix-turn-helix motif with score 2116.000, SD 6.39 at aa 2-23, sequence VTLKDIAALAKVSPATVSRVLN
553482009152	PS00356 Bacterial regulatory proteins, lacI family signature.
553482009153	galactokinase; Provisional; Region: PRK05322
553482009154	Galactokinase galactose-binding signature; Region: GalKase_gal_bdg; pfam10509
553482009155	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
553482009156	GHMP kinases C terminal; Region: GHMP_kinases_C; pfam08544
553482009157	PS00106 Galactokinase signature.
553482009158	HMMPfam hit to PF00288, GHMP kinases N terminal domain, score 1.4e-19
553482009159	PS00627 GHMP kinases ATP-binding domain.
553482009160	PS00012 Phosphopantetheine attachment site.
553482009161	HMMPfam hit to PF08544, GHMP kinases C terminal, score 6.7e-15
553482009162	galactose-1-phosphate uridylyltransferase; Provisional; Region: PRK05270
553482009163	Galactose-1-phosphate uridyl transferase, N-terminal domain; Region: GalP_UDP_transf; pfam01087
553482009164	Galactose-1-phosphate uridyl transferase, C-terminal domain; Region: GalP_UDP_tr_C; pfam02744
553482009165	HMMPfam hit to PF01087, Galactose-1-phosphate uridyl transfer, score 7.5e-89
553482009166	HMMPfam hit to PF02744, Galactose-1-phosphate uridyl transfer, score 6.4e-89
553482009167	UDP-glucose 4-epimerase [Cell envelope biogenesis, outer membrane]; Region: GalE; COG1087
553482009168	UDP-glucose 4 epimerase, subgroup 1, extended (e) SDRs; Region: UDP_G4E_1_SDR_e; cd05247
553482009169	NAD binding site [chemical binding]; other site
553482009170	homodimer interface [polypeptide binding]; other site
553482009171	active site
553482009172	substrate binding site [chemical binding]; other site
553482009173	HMMPfam hit to PF04321, RmlD substrate binding domain, score 0.00068
553482009174	HMMPfam hit to PF01370, NAD dependent epimerase/dehydratase f, score 2.5e-76
553482009175	HMMPfam hit to PF02719, Polysaccharide biosynthesis protein, score 4.6e-05
553482009176	HMMPfam hit to PF01073, 3-beta hydroxysteroid dehydrogenase/i, score 8.8e-09
553482009177	HMMPfam hit to PF07993, Male sterility protein, score 0.00044
553482009178	galactose mutarotase_like; Region: galactose_mutarotase_like; cd09019
553482009179	active site
553482009180	catalytic residues [active]
553482009181	HMMPfam hit to PF01263, Aldose 1-epimerase, score 3e-79
553482009182	PS00545 Aldose 1-epimerase active site.
553482009183	gene remnant. CDS contains at least two frameshifts. Similar to an internal region of Streptococcus pneumoniae transposase, IS200 family UniProt:Q97CV4 (EMBL:AE005672 (157 aa) fasta scores: E()=3.6e-16, 58.750% id in 80 aa
553482009184	gene remnant. CDS contains several frameshift and nonsense mutations. Similar to the C-terminal region of Streptococcus suis transposase UniProt:Q2ZZ41 (EMBL:AAFA02000065 (430 aa) fasta scores: E()=1.3e-25, 50.000% id in 192 aa
553482009185	genomic island
553482009186	Plasmid stabilization system protein [General function prediction only]; Region: ParE; COG3668
553482009187	HMMPfam hit to PF05016, Plasmid stabilisation system protein, score 9.7e-13
553482009188	RelB antitoxin; Region: RelB; cl01171
553482009189	HMMPfam hit to PF04221, RelB antitoxin, score 0.011
553482009190	Predicted transcriptional regulator containing an HTH domain and an uncharacterized domain shared with the mammalian protein Schlafen [Transcription]; Region: COG2865
553482009191	Divergent AAA domain; Region: AAA_4; pfam04326
553482009192	ATP-dependent DNA helicase recG C-terminal; Region: HATPase_c_4; pfam13749
553482009193	HMMPfam hit to PF04326, Divergent AAA domain, score 3.2e-10
553482009194	PS00215 Mitochondrial energy transfer proteins signature.
553482009195	Type I site-specific restriction-modification system, R (restriction) subunit and related helicases [Defense mechanisms]; Region: COG0610
553482009196	Type I restriction enzyme R protein N terminus (HSDR_N); Region: HSDR_N; pfam04313
553482009197	Type III restriction enzyme, res subunit; Region: ResIII; pfam04851
553482009198	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
553482009199	ATP binding site [chemical binding]; other site
553482009200	putative Mg++ binding site [ion binding]; other site
553482009201	PS00017 ATP/GTP-binding site motif A (P-loop).
553482009202	HMMPfam hit to PF04851, Type III restriction enzyme, res subunit, score 6e-49
553482009203	HMMPfam hit to PF04313, Type I restriction enzyme R protein N termin, score 2.7e-51
553482009204	AAA domain; Region: AAA_13; pfam13166
553482009205	PS00017 ATP/GTP-binding site motif A (P-loop).
553482009206	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
553482009207	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
553482009208	Restriction endonuclease S subunits [Defense mechanisms]; Region: HsdS; COG0732
553482009209	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
553482009210	HMMPfam hit to PF01420, Type I restriction modification DNA speci, score 1.8e-17
553482009211	HMMPfam hit to PF01420, Type I restriction modification DNA speci, score 1.9e-18
553482009212	HMMPfam hit to PF01420, Type I restriction modification DNA speci, score 8e-10
553482009213	type I restriction system adenine methylase (hsdM); Region: hsdM; TIGR00497
553482009214	HsdM N-terminal domain; Region: HsdM_N; pfam12161
553482009215	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
553482009216	S-adenosylmethionine binding site [chemical binding]; other site
553482009217	HMMPfam hit to PF02384, N-6 DNA Methylase, score 1.1e-169
553482009218	PS00092 N-6 Adenine-specific DNA methylases signature.
553482009219	Replication initiation and membrane attachment; Region: DnaB_2; cl12121
553482009220	Predicted helix-turn-helix motif with score 1500.000, SD 4.30 at aa 45-66, sequence VRMAALSRWLDVSTTTLQKWTR
553482009221	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
553482009222	non-specific DNA binding site [nucleotide binding]; other site
553482009223	salt bridge; other site
553482009224	sequence-specific DNA binding site [nucleotide binding]; other site
553482009225	Temperature dependent protein affecting M2 dsRNA replication; Region: MKT1_N; pfam12247
553482009226	HMMPfam hit to PF01381, Helix-turn-helix, score 3.7e-10
553482009227	Predicted helix-turn-helix motif with score 1361.000, SD 3.82 at aa 14-35, sequence KKIKSISEALDISYPTLSSYNQ
553482009228	Site-specific recombinase XerD [DNA replication, recombination, and repair]; Region: XerD; COG4974
553482009229	phiLC3 phage and phage-related integrases, site-specific recombinases, DNA breaking-rejoining enzymes, C-terminal catalytic domain. This CD includes various bacterial (mainly gram positive) and phage integrases, including those similar to Lactococcus...; Region: INT_phiLC3_C; cd01189
553482009230	Int/Topo IB signature motif; other site
553482009231	HMMPfam hit to PF00589, Phage integrase family, score 1.3e-19
553482009232	30S ribosomal protein S9; Reviewed; Region: rpsI; PRK00132
553482009233	HMMPfam hit to PF00380, Ribosomal protein S9/S16, score 6.5e-59
553482009234	PS00360 Ribosomal protein S9 signature.
553482009235	Ribosomal protein L13.  Protein L13, a large ribosomal subunit protein, is one of five proteins required for an early folding intermediate of 23S rRNA in the assembly of the large subunit. L13 is situated on the bottom of the large subunit, near the...; Region: Ribosomal_L13; cd00392
553482009236	23S rRNA interface [nucleotide binding]; other site
553482009237	L3 interface [polypeptide binding]; other site
553482009238	HMMPfam hit to PF00572, Ribosomal protein L13, score 2.8e-68
553482009239	PS00783 Ribosomal protein L13 signature.
553482009240	EDD domain protein, DegV family; Region: DegV; TIGR00762
553482009241	Uncharacterized protein, DegV family COG1307; Region: DegV; pfam02645
553482009242	HMMPfam hit to PF02645, Uncharacterized protein, DegV family COG1307, score 5.3e-72
553482009243	YacP-like NYN domain; Region: NYN_YacP; cl01491
553482009244	HMMPfam hit to PF05991, Protein of unknown function (DUF901), score 1.1e-82
553482009245	rRNA methylases [Translation, ribosomal structure and biogenesis]; Region: SpoU; COG0566
553482009246	RNA 2'-O ribose methyltransferase substrate binding; Region: SpoU_sub_bind; pfam08032
553482009247	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
553482009248	HMMPfam hit to PF00588, SpoU rRNA Methylase family, score 9e-62
553482009249	HMMPfam hit to PF08032, RNA 2'-O ribose methyltransferase subs, score 1.8e-12
553482009250	2 transmembrane helices predicted for SEQ1990 by TMHMM2.0 at aa 7-29 and 237-259
553482009251	RIBOc. Ribonuclease III C terminal domain. This group consists of eukaryotic, bacterial and archeal ribonuclease III (RNAse III) proteins. RNAse III is a double stranded RNA-specific endonuclease. Prokaryotic RNAse III is important in...; Region: RIBOc; cd00593
553482009252	active site
553482009253	metal binding site [ion binding]; metal-binding site
553482009254	dimerization interface [polypeptide binding]; other site
553482009255	1 transmembrane helix predicted for SEQ1991 by TMHMM2.0 at aa 5-27
553482009256	cysteinyl-tRNA synthetase; Validated; Region: cysS; PRK00260
553482009257	catalytic core domain of cysteinyl tRNA synthetase; Region: CysRS_core; cd00672
553482009258	active site
553482009259	HIGH motif; other site
553482009260	catalytic core domain of cysteinyl tRNA synthetase; Region: CysRS_core; cd00672
553482009261	KMSKS motif; other site
553482009262	Anticodon-binding domain of class Ia aminoacyl tRNA synthetases and similar domains; Region: Anticodon_Ia_like; cl12020
553482009263	tRNA binding surface [nucleotide binding]; other site
553482009264	anticodon binding site; other site
553482009265	HMMPfam hit to PF01406, tRNA synthetases class I (C) catalytic d, score 1.6e-185
553482009266	serine O-acetyltransferase; Region: cysE; TIGR01172
553482009267	Serine acetyltransferase (SAT): SAT catalyzes the CoA-dependent acetylation of the side chain hydroxyl group of L-serine to form O-acetylserine, as the first step of a two-step biosynthetic pathway in bacteria and plants leading to the formation of...; Region: LbH_SAT; cd03354
553482009268	trimer interface [polypeptide binding]; other site
553482009269	active site
553482009270	substrate binding site [chemical binding]; other site
553482009271	CoA binding site [chemical binding]; other site
553482009272	PS00017 ATP/GTP-binding site motif A (P-loop).
553482009273	HMMPfam hit to PF00132, Bacterial transferase hexapeptide (three rep, score 10
553482009274	HMMPfam hit to PF00132, Bacterial transferase hexapeptide (three rep, score 3.6
553482009275	HMMPfam hit to PF00132, Bacterial transferase hexapeptide (three rep, score 9
553482009276	polynucleotide phosphorylase/polyadenylase; Provisional; Region: PRK11824
553482009277	Polyribonucleotide nucleotidyltransferase, repeat 1; Region: RNase_PH_PNPase_1; cd11363
553482009278	RNase E interface [polypeptide binding]; other site
553482009279	trimer interface [polypeptide binding]; other site
553482009280	Polyribonucleotide nucleotidyltransferase, repeat 2; Region: RNase_PH_PNPase_2; cd11364
553482009281	RNase E interface [polypeptide binding]; other site
553482009282	trimer interface [polypeptide binding]; other site
553482009283	active site
553482009284	Polynucleotide phosphorylase (PNPase) K homology RNA-binding domain (KH). PNPase is a polyribonucleotide nucleotidyl transferase that degrades mRNA in prokaryotes and plant chloroplasts. The C-terminal region of PNPase contains domains homologous to...; Region: PNPase_KH; cd02393
553482009285	S1_PNPase: Polynucleotide phosphorylase (PNPase), ), S1-like RNA-binding domain. PNPase  is a polyribonucleotide nucleotidyl transferase that degrades mRNA. It is a trimeric multidomain protein. The C-terminus contains the S1 domain which binds ssRNA; Region: S1_PNPase; cd04472
553482009286	RNA binding site [nucleotide binding]; other site
553482009287	HMMPfam hit to PF00575, S1 RNA binding domain, score 1e-21
553482009288	HMMPfam hit to PF00013, KH domain, score 1.9e-15
553482009289	HMMPfam hit to PF03725, 3' exoribonuclease family, domain, score 2.4e-25
553482009290	HMMPfam hit to PF01138, 3' exoribonuclease family, domain, score 1.5e-43
553482009291	HMMPfam hit to PF03726, Polyribonucleotide nucleotidyltransferase,, score 3e-09
553482009292	HMMPfam hit to PF03725, 3' exoribonuclease family, domain, score 1.8e-13
553482009293	HMMPfam hit to PF01138, 3' exoribonuclease family, domain, score 2.3e-27
553482009294	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
553482009295	Transposase; Region: HTH_Tnp_1; cl17663
553482009296	HMMPfam hit to PF01527, Transposase, score 0.00051
553482009297	putative transposase OrfB; Reviewed; Region: PHA02517
553482009298	HTH-like domain; Region: HTH_21; pfam13276
553482009299	Integrase core domain; Region: rve; pfam00665
553482009300	Integrase core domain; Region: rve_2; pfam13333
553482009301	HMMPfam hit to PF00665, Integrase core domain, score 2.2e-37
553482009302	Ribosomal protein S15 (prokaryotic)_S13 (eukaryotic) binds the central domain of 16S rRNA and is required for assembly of the small ribosomal subunit and for intersubunit association, thus representing a key element in the assembly of the whole ribosome; Region: Ribosomal_S15p_S13e; cd00353
553482009303	16S/18S rRNA binding site [nucleotide binding]; other site
553482009304	S13e-L30e interaction site [polypeptide binding]; other site
553482009305	25S rRNA binding site [nucleotide binding]; other site
553482009306	HMMPfam hit to PF00312, Ribosomal protein S15, score 1.9e-34
553482009307	Fibronectin-binding protein signal sequence; Region: Fb_signal; pfam08341
553482009308	TQXA domain; Region: TQXA_dom; TIGR03934
553482009309	Fibronectin binding repeat; Region: Fn_bind; pfam02986
553482009310	Fibronectin binding repeat; Region: Fn_bind; pfam02986
553482009311	Fibronectin binding repeat; Region: Fn_bind; pfam02986
553482009312	Fibronectin binding repeat; Region: Fn_bind; pfam02986
553482009313	2 transmembrane helices predicted for SEQ1999 by TMHMM2.0 at aa 12-34 and 450-469
553482009314	HMMPfam hit to PF02986, Fibronectin binding repeat, score 1e-15
553482009315	HMMPfam hit to PF02986, Fibronectin binding repeat, score 2.1e-15
553482009316	HMMPfam hit to PF02986, Fibronectin binding repeat, score 6e-13
553482009317	HMMPfam hit to PF02986, Fibronectin binding repeat, score 0.0044
553482009318	HMMPfam hit to PF08341, Fibronectin-binding protein signal sequence, score 1.6e-25
553482009319	Polypeptide or peptide deformylase; a family of metalloenzymes that catalyzes the removal of the N-terminal formyl group in a growing polypeptide chain following translation initiation during protein synthesis in prokaryotes. These enzymes utilize Fe(II)...; Region: Pep_deformylase; cd00487
553482009320	active site
553482009321	catalytic residues [active]
553482009322	metal binding site [ion binding]; metal-binding site
553482009323	HMMPfam hit to PF01327, Polypeptide deformylase, score 2e-86
553482009324	Predicted flavoprotein [General function prediction only]; Region: COG0431
553482009325	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
553482009326	HMMPfam hit to PF02525, Flavodoxin-like fold, score 3.8e-05
553482009327	HMMPfam hit to PF03358, NADPH-dependent FMN reductase, score 4.4e-18
553482009328	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
553482009329	MarR family; Region: MarR; pfam01047
553482009330	HMMPfam hit to PF01047, MarR family, score 1.4e-21
553482009331	DNA polymerase III PolC; Validated; Region: polC; PRK00448
553482009332	DNA polymerase III polC-type N-terminus; Region: DNA_pol3_alph_N; pfam11490
553482009333	polC_OBF: A subfamily of OB folds corresponding to the N-terminal OB-fold nucleic acid binding domain of Bacillus subtilis type C replicative DNA polymerase III alpha subunit (polC). Replication in B. subtilis and Staphylococcus aureus requires two...; Region: polC_OBF; cd04484
553482009334	generic binding surface II; other site
553482009335	generic binding surface I; other site
553482009336	Polymerase and Histidinol Phosphatase domain; Region: PHP; cl17102
553482009337	active site
553482009338	DEDDh 3'-5' exonuclease domain family; Region: DEDDh; cd06127
553482009339	active site
553482009340	catalytic site [active]
553482009341	substrate binding site [chemical binding]; other site
553482009342	Polymerase and Histidinol Phosphatase domain of alpha-subunit of bacterial polymerase III at PolC gene; Region: PHP_PolIIIA_POLC; cd07435
553482009343	HMMPfam hit to PF07733, Bacterial DNA polymerase III alpha sub, score 3.2e-191
553482009344	HMMPfam hit to PF02811, PHP domain, score 9.8e-34
553482009345	HMMPfam hit to PF00929, Exonuclease, score 5e-41
553482009346	HMMPfam hit to PF01336, OB-fold nucleic acid binding domain, score 3.4e-06
553482009347	Bacterial protein of unknown function (DUF925); Region: DUF925; pfam06042
553482009348	HMMPfam hit to PF06042, Bacterial protein of unknown function (DUF92, score 2.6e-78
553482009349	prolyl-tRNA synthetase; Provisional; Region: PRK09194
553482009350	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
553482009351	motif 1; other site
553482009352	dimer interface [polypeptide binding]; other site
553482009353	active site
553482009354	motif 2; other site
553482009355	INS is an amino acid-editing domain inserted (INS) into the bacterial class II prolyl-tRNA synthetase (ProRS) however, this CD is not exclusively bacterial. It is also found at the N-terminus of the eukaryotic/archaea-like ProRS's of yeasts and...; Region: ProRS-INS; cd04334
553482009356	putative deacylase active site [active]
553482009357	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
553482009358	active site
553482009359	motif 3; other site
553482009360	ProRS Prolyl-anticodon binding domain, short version found predominantly in bacteria. ProRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding; Region: ProRS_anticodon_short; cd00861
553482009361	anticodon binding site; other site
553482009362	HMMPfam hit to PF03129, Anticodon binding domain, score 1.6e-18
553482009363	HMMPfam hit to PF04073, YbaK / prolyl-tRNA synthetases associa, score 5.5e-35
553482009364	HMMPfam hit to PF00587, tRNA synthetase class II core domain (, score 1.4e-46
553482009365	PS00179 Aminoacyl-transfer RNA synthetases class-II signature 1.
553482009366	RIP metalloprotease RseP; Region: TIGR00054
553482009367	RseP-like Site-2 proteases (S2P), zinc metalloproteases (MEROPS family M50A), cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. In Escherichia coli, the S2P homolog...; Region: S2P-M50_PDZ_RseP-like; cd06163
553482009368	active site
553482009369	Site-2 protease (S2P) class of zinc metalloproteases (MEROPS family M50) cleaves transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. Members of this family use proteolytic...; Region: S2P-M50; cl10020
553482009370	PDZ domain of bacterial and plant zinc metalloprotases, presumably membrane-associated or integral membrane proteases, which may be involved in signalling and regulatory mechanisms. May be responsible for substrate recognition and/or binding, as most PDZ...; Region: PDZ_metalloprotease; cd00989
553482009371	RseP-like Site-2 proteases (S2P), zinc metalloproteases (MEROPS family M50A), cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. In Escherichia coli, the S2P homolog...; Region: S2P-M50_PDZ_RseP-like; cd06163
553482009372	putative substrate binding region [chemical binding]; other site
553482009373	HMMPfam hit to PF02163, Peptidase family M50, score 1.2e-95
553482009374	5 transmembrane helices predicted for SEQ2006 by TMHMM2.0 at aa 4-26, 169-191, 300-322, 343-365 and 392-411
553482009375	PS00142 Neutral zinc metallopeptidases, zinc-binding region signature.
553482009376	CDP-diglyceride synthetase [Lipid metabolism]; Region: CdsA; COG0575
553482009377	Cytidylyltransferase family; Region: CTP_transf_1; pfam01148
553482009378	HMMPfam hit to PF01148, Cytidylyltransferase family, score 7.9e-95
553482009379	PS01315 Phosphatidate cytidylyltransferase signature.
553482009380	7 transmembrane helices predicted for SEQ2007 by TMHMM2.0 at aa 7-29, 49-68, 80-97, 107-126, 135-157, 172-191 and 196-218
553482009381	Undecaprenyl pyrophosphate synthase [Lipid metabolism]; Region: UppS; COG0020
553482009382	Cis (Z)-Isoprenyl Diphosphate Synthases (cis-IPPS); homodimers which catalyze the successive 1'-4 condensation of the isopentenyl diphosphate (IPP) molecule to trans,trans-farnesyl diphosphate (FPP) or to cis,trans-FPP to form long-chain polyprenyl...; Region: CIS_IPPS; cd00475
553482009383	catalytic residue [active]
553482009384	putative FPP diphosphate  binding site; other site
553482009385	putative FPP binding hydrophobic cleft; other site
553482009386	dimer interface [polypeptide binding]; other site
553482009387	putative IPP diphosphate binding site; other site
553482009388	HMMPfam hit to PF01255, undecaprenyl diphosphate syntha, score 6.4e-109
553482009389	PS01066 Undecaprenyl pyrophosphate synthetase family signature.
553482009390	preprotein translocase subunit YajC; Validated; Region: yajC; PRK06531
553482009391	HMMPfam hit to PF02699, Preprotein translocase subunit, score 2.7e-09
553482009392	1 transmembrane helix predicted for SEQ2009 by TMHMM2.0 at aa 5-19
553482009393	CDS contains a nonsense mutation (amber) after codon 17. Similar to Streptococcus pyogenes serotype M6 thioredoxin UniProt:Q5X9U2 (EMBL:CP000003 (124 aa) fasta scores: E()=9.8e-22, 57.391% id in 115 aa
553482009394	alpha,alpha-phosphotrehalase; Region: trehalose_treC; TIGR02403
553482009395	Alpha amylase catalytic domain found in Sucrose isomerases, oligo-1,6-glucosidase (also called isomaltase; sucrase-isomaltase; alpha-limit dextrinase), dextran glucosidase (also called glucan 1,6-alpha-glucosidase), and related proteins; Region: AmyAc_SI_OligoGlu_DGase; cd11333
553482009396	Ca binding site [ion binding]; other site
553482009397	active site
553482009398	catalytic site [active]
553482009399	HMMPfam hit to PF00128, Alpha amylase, catalytic domain, score 5.3e-136
553482009400	glycerol-3-phosphate transporter ATP-binding subunit; Provisional; Region: ugpC; PRK11650
553482009401	The N-terminal ATPase domain of the maltose transporter, MalK; Region: ABC_MalK_N; cd03301
553482009402	Walker A/P-loop; other site
553482009403	ATP binding site [chemical binding]; other site
553482009404	Q-loop/lid; other site
553482009405	ABC transporter signature motif; other site
553482009406	Walker B; other site
553482009407	D-loop; other site
553482009408	H-loop/switch region; other site
553482009409	TOBE domain; Region: TOBE; pfam03459
553482009410	HMMPfam hit to PF08402, TOBE domain, score 2.4e-10
553482009411	HMMPfam hit to PF03459, TOBE domain, score 2.1e-08
553482009412	HMMPfam hit to PF00005, ABC transporter, score 5.3e-57
553482009413	PS00211 ABC transporters family signature.
553482009414	PS00017 ATP/GTP-binding site motif A (P-loop).
553482009415	Regulator of polyketide synthase expression [Signal transduction mechanisms / Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG2508
553482009416	PucR C-terminal helix-turn-helix domain; Region: HTH_30; pfam13556
553482009417	HMMPfam hit to PF02954, Bacterial regulatory protein, Fis family, score 0.0044
553482009418	Staphylokinase/Streptokinase family; Region: Staphylokinase; pfam02821
553482009419	HMMPfam hit to PF02821, Staphylokinase/Streptokinase family, score 4.5e-10
553482009420	D-Tyrosyl-tRNAtyr deacylases; a class of tRNA-dependent hydrolases which are capable of hydrolyzing the ester bond of D-Tyrosyl-tRNA reducing the level of cellular D-Tyrosine while recycling the peptidyl-tRNA; found in bacteria and in eukaryotes but not...; Region: Dtyr_deacylase; cd00563
553482009421	putative active site [active]
553482009422	dimerization interface [polypeptide binding]; other site
553482009423	putative tRNAtyr binding site [nucleotide binding]; other site
553482009424	HMMPfam hit to PF02580, D-Tyr-tRNA(Tyr) deacylase, score 2.1e-80
553482009425	Guanosine polyphosphate pyrophosphohydrolases/synthetases [Signal transduction mechanisms / Transcription]; Region: SpoT; COG0317
553482009426	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
553482009427	Zn2+ binding site [ion binding]; other site
553482009428	Mg2+ binding site [ion binding]; other site
553482009429	Nucleotidyltransferase (NT) domain of RelA- and SpoT-like ppGpp synthetases and hydrolases; Region: NT_Rel-Spo_like; cd05399
553482009430	synthetase active site [active]
553482009431	NTP binding site [chemical binding]; other site
553482009432	metal binding site [ion binding]; metal-binding site
553482009433	TGS_RelA_SpoT: The RelA (SpoT) protein, also referred to as ppGpp hydrolase/synthetase, is a ribosome-associated protein that is activated during amino acid starvation and thought to mediate the stringent response. RelA contains a TGS domain, named after...; Region: TGS_RelA_SpoT; cd01668
553482009434	ACT  domain found C-terminal of the RelA/SpoT domains; Region: ACT_RelA-SpoT; cd04876
553482009435	HMMPfam hit to PF01842, ACT domain, score 1.5e-07
553482009436	HMMPfam hit to PF02824, TGS domain, score 1.6e-27
553482009437	HMMPfam hit to PF04607, Region found in RelA / SpoT proteins, score 3.4e-47
553482009438	HMMPfam hit to PF01966, HD domain, score 3.9e-14
553482009439	Gram-positive signal peptide, YSIRK family; Region: YSIRK_signal; TIGR01168
553482009440	Gram positive anchor; Region: Gram_pos_anchor; pfam00746
553482009441	HMMPfam hit to PF00746, Gram positive anchor, score 5.2e-12
553482009442	PS00343 Gram-positive cocci surface proteins 'anchoring' hexapeptide.
553482009443	HMMPfam hit to PF04650, YSIRK type signal peptide, score 4.3e-12
553482009444	YSIRK-targeted surface antigen transcriptional regulator; Region: adjacent_YSIRK; TIGR04094
553482009445	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
553482009446	Predicted helix-turn-helix motif with score 2064.000, SD 6.22 at aa 309-330, sequence VTTAELAQHFNMSESKLRQIFK
553482009447	PS00041 Bacterial regulatory proteins, araC family signature.
553482009448	HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix protei, score 1.1e-07
553482009449	flavoprotein NrdI; Provisional; Region: PRK02551
553482009450	HMMPfam hit to PF07972, NrdI Flavodoxin like, score 1.1e-67
553482009451	Streptococcus agalactiae RgfB, part of a putative two component signal transduction system, and related proteins; Region: RgfB-like; cd09079
553482009452	putative catalytic site [active]
553482009453	putative metal binding site [ion binding]; other site
553482009454	putative phosphate binding site [ion binding]; other site
553482009455	HMMPfam hit to PF03372, Endonuclease/Exonuclease/phosphatase fa, score 4.4e-09
553482009456	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
553482009457	PTS system, IIBC component; Region: PTS-II-BC-unk1; TIGR02003
553482009458	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
553482009459	active site turn [active]
553482009460	phosphorylation site [posttranslational modification]
553482009461	Phosphotransferase system IIA components [Carbohydrate transport and metabolism]; Region: NagE; COG2190
553482009462	HPr interaction site; other site
553482009463	glycerol kinase (GK) interaction site [polypeptide binding]; other site
553482009464	active site
553482009465	phosphorylation site [posttranslational modification]
553482009466	HMMPfam hit to PF00358, phosphoenolpyruvate-dependent sugar phosph, score 2.4e-53
553482009467	PS00371 PTS EIIA domains phosphorylation site signature 1.
553482009468	HMMPfam hit to PF00367, phosphotransferase system, EIIB, score 3.8e-16
553482009469	PS01035 PTS EIIB domains cysteine phosphorylation site signature.
553482009470	9 transmembrane helices predicted for SEQ2021 by TMHMM2.0 at aa 20-42, 57-79, 86-108, 141-163, 184-206, 312-329, 341-358, 363-385 and 418-440
553482009471	HMMPfam hit to PF02378, Phosphotransferase system, EIIC, score 3e-45
553482009472	Transcriptional regulators [Transcription]; Region: PurR; COG1609
553482009473	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
553482009474	DNA binding site [nucleotide binding]
553482009475	domain linker motif; other site
553482009476	Type 1 periplasmic binding fold superfamily; Region: Periplasmic_Binding_Protein_Type_1; cl10011
553482009477	HMMPfam hit to PF00532, Periplasmic binding proteins and sugar b, score 0.00015
553482009478	HMMPfam hit to PF00356, Bacterial regulatory proteins, lacI fami, score 3.2e-10
553482009479	Predicted helix-turn-helix motif with score 2421.000, SD 7.43 at aa 2-23, sequence VTIKDVARLAGVSPSTASRAIN
553482009480	PS00356 Bacterial regulatory proteins, lacI family signature.
553482009481	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1385
553482009482	RNA methyltransferase, RsmE family; Region: TIGR00046
553482009483	HMMPfam hit to PF04452, Protein of unknown function (DUF558), score 2.6e-91
553482009484	Ribosomal protein L11 methyltransferase (PrmA); Region: PrmA; pfam06325
553482009485	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
553482009486	S-adenosylmethionine binding site [chemical binding]; other site
553482009487	HMMPfam hit to PF06325, Ribosomal protein L11 methyltransfera, score 3e-157
553482009488	HMMPfam hit to PF05175, Methyltransferase small domain, score 7.3e-07
553482009489	HMMPfam hit to PF08241, Methyltransferase domain, score 0.0015
553482009490	Streptococcal histidine triad protein; Region: Strep_his_triad; pfam04270
553482009491	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482009492	HMMPfam hit to PF04270, Streptococcal histidine triad protein, score 1.3e-05
553482009493	HMMPfam hit to PF04270, Streptococcal histidine triad protein, score 0.0049
553482009494	Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly...; Region: Nudix_Hydrolase_23; cd04682
553482009495	nudix motif; other site
553482009496	HMMPfam hit to PF00293, NUDIX domain, score 4.7e-11
553482009497	ASC-1 homology domain, subfamily similar to Pyrococcus furiosus Pf0470. The ASCH domain, a small beta-barrel domain found in all three kingdoms of life, resembles the RNA-binding PUA domain and may also interact with RNA. ASCH has been proposed to...; Region: ASCH_PF0470_like; cd06555
553482009498	HMMPfam hit to PF07060, ProFAR isomerase associated, score 2e-17
553482009499	Protein of unknown function (DUF3013); Region: DUF3013; pfam11217
553482009500	aminodeoxychorismate synthase; Provisional; Region: PRK07508
553482009501	chorismate binding enzyme; Region: Chorismate_bind; cl10555
553482009502	PyridoxaL 5'-Phosphate Dependent Enzymes class IV (PLPDE_IV). This D-amino acid superfamily, one of five classes of PLPDE, consists of branched-chain amino acid aminotransferases (BCAT), D-amino acid transferases (DAAT), and...; Region: PLPDE_IV; cl00224
553482009503	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase [Amino acid transport and metabolism / Coenzyme metabolism]; Region: IlvE; COG0115
553482009504	substrate-cofactor binding pocket; other site
553482009505	pyridoxal 5'-phosphate binding site [chemical binding]; other site
553482009506	catalytic residue [active]
553482009507	HMMPfam hit to PF00425, chorismate binding enzyme, score 3.6e-70
553482009508	PS00770 Aminotransferases class-IV signature.
553482009509	Type 1 glutamine amidotransferase (GATase1) domain found in Anthranilate synthase; Region: GATase1_Anthranilate_Synthase; cd01743
553482009510	Glutamine amidotransferase class-I; Region: GATase; pfam00117
553482009511	glutamine binding [chemical binding]; other site
553482009512	catalytic triad [active]
553482009513	HMMPfam hit to PF00117, Glutamine amidotransferase class-I, score 4.7e-66
553482009514	PS00442 Glutamine amidotransferases class-I active site.
553482009515	recombination factor protein RarA; Reviewed; Region: PRK13342
553482009516	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
553482009517	Walker A motif; other site
553482009518	ATP binding site [chemical binding]; other site
553482009519	Walker B motif; other site
553482009520	arginine finger; other site
553482009521	MgsA AAA+ ATPase C terminal; Region: MgsA_C; pfam12002
553482009522	HMMPfam hit to PF00004, ATPase family associated with various cellul, score 3.4e-17
553482009523	HMMPfam hit to PF07728, ATPase family associated with various cellul, score 0.00056
553482009524	PS00017 ATP/GTP-binding site motif A (P-loop).
553482009525	putative transposase OrfB; Reviewed; Region: PHA02517
553482009526	HTH-like domain; Region: HTH_21; pfam13276
553482009527	Integrase core domain; Region: rve; pfam00665
553482009528	Integrase core domain; Region: rve_2; pfam13333
553482009529	HMMPfam hit to PF00665, Integrase core domain, score 7.5e-38
553482009530	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
553482009531	Transposase; Region: HTH_Tnp_1; cl17663
553482009532	HMMPfam hit to PF01527, Transposase, score 0.00051
553482009533	CDS is truncated by the insertion of the downstream prophage. N-terminal region is similar to the N-terminus of Streptococcus pyogenes serotype M18 repressor protein UniProt:Q8P1T3 (EMBL:AE010005 (254 aa) fasta scores: E()=0.00048, 36.232% id in 138 aa
553482009534	HMMPfam hit to PF01381, Helix-turn-helix, score 2.2e-15
553482009535	PS00017 ATP/GTP-binding site motif A (P-loop).
553482009536	Predicted helix-turn-helix motif with score 1936.000, SD 5.78 at aa 26-47, sequence KTQKELAKLIGVTKQTIINDEK
553482009537	prophage phiSeq4
553482009538	Staphylococcal/Streptococcal toxin, OB-fold domain; Region: Stap_Strp_toxin; pfam01123
553482009539	Staphylococcal/Streptococcal toxin, beta-grasp domain; Region: Stap_Strp_tox_C; pfam02876
553482009540	HMMPfam hit to PF02876, Staphylococcal/Streptococcal toxin, b, score 9e-17
553482009541	PS00278 Staphyloccocal enterotoxin/Streptococcal pyrogenic exotoxin signature 2.
553482009542	HMMPfam hit to PF01123, Staphylococcal/Streptococcal toxin, O, score 1.6e-29
553482009543	1 transmembrane helix predicted for SEQ2036 by TMHMM2.0 at aa 13-35
553482009544	Staphylococcal/Streptococcal toxin, OB-fold domain; Region: Stap_Strp_toxin; pfam01123
553482009545	Staphylococcal/Streptococcal toxin, beta-grasp domain; Region: Stap_Strp_tox_C; pfam02876
553482009546	HMMPfam hit to PF02876, Staphylococcal/Streptococcal toxin, b, score 1.3e-25
553482009547	PS00278 Staphyloccocal enterotoxin/Streptococcal pyrogenic exotoxin signature 2.
553482009548	PS00277 Staphylococcal enterotoxin/Streptococcal pyrogenic exotoxin signature 1.
553482009549	HMMPfam hit to PF01123, Staphylococcal/Streptococcal toxin, O, score 1.4e-32
553482009550	1 transmembrane helix predicted for SEQ2037 by TMHMM2.0 at aa 13-35
553482009551	CHAP domain; Region: CHAP; pfam05257
553482009552	Lyzozyme M1 (1,4-beta-N-acetylmuramidase) [Cell envelope biogenesis, outer membrane]; Region: Acm; COG3757
553482009553	Cpl-1 lysin (also known as Cpl-9 lysozyme / muramidase) is a bacterial cell wall endolysin encoded by the pneumococcal bacteriophage Cp-1, which cleaves the glycosidic N-acetylmuramoyl-(beta1,4)-N-acetylglucosamine bonds of the pneumococcal glycan chain; Region: GH25_Cpl1-like; cd06415
553482009554	active site
553482009555	Bacterial SH3 domain; Region: SH3_3; cl17532
553482009556	HMMPfam hit to PF01183, Glycosyl hydrolases family, score 1.2e-75
553482009557	HMMPfam hit to PF05257, CHAP domain, score 4.2e-30
553482009558	1 transmembrane helix predicted for SEQ2039 by TMHMM2.0 at aa 7-29
553482009559	Small integral membrane protein [Function unknown]; Region: COG5546
553482009560	HMMPfam hit to PF04531, Bacteriophage holin, score 6.9e-51
553482009561	1 transmembrane helix predicted for SEQ2040 by TMHMM2.0 at aa 12-30
553482009562	1 transmembrane helix predicted for SEQ2041 by TMHMM2.0 at aa 5-24
553482009563	Protein of unknown function (DUF1617); Region: DUF1617; pfam07761
553482009564	HMMPfam hit to PF07761, Protein of unknown function (DUF1617), score 6.3e-106
553482009565	gp58-like protein; Region: Gp58; pfam07902
553482009566	HMMPfam hit to PF07902, gp58-like protein, score 0
553482009567	Collagen triple helix repeat (20 copies); Region: Collagen; pfam01391
553482009568	Hyaluronidase protein (HylP); Region: Hyaluronidase_1; pfam07212
553482009569	HMMPfam hit to PF07212, Hyaluronidase protein (HylP), score 6e-212
553482009570	Prophage endopeptidase tail; Region: Prophage_tail; pfam06605
553482009571	HMMPfam hit to PF06605, Protein of unknown function (DUF1142), score 0.00056
553482009572	hypothetical protein; Region: PHA01795
553482009573	PS00017 ATP/GTP-binding site motif A (P-loop).
553482009574	tape measure domain; Region: tape_meas_nterm; TIGR02675
553482009575	PS00678 Trp-Asp (WD) repeats signature.
553482009576	4 transmembrane helices predicted for SEQ2048 by TMHMM2.0 at aa 619-641, 648-670, 674-696 and 709-731
553482009577	hypothetical protein; Region: PHA01794
553482009578	phage major tail protein, TP901-1 family; Region: phgtail_TP901_1; TIGR02126
553482009579	HMMPfam hit to PF06199, Phage major tail protein, score 1.3e-91
553482009580	Bacteriophage protein of unknown function (DUF646); Region: DUF646; pfam04883
553482009581	HMMPfam hit to PF07772, TP901-1 ORF40-like protein, score 2.3e-37
553482009582	Phage gp6-like head-tail connector protein; Region: Phage_connect_1; pfam05135
553482009583	Domain of unknown function (DUF4355); Region: DUF4355; pfam14265
553482009584	1 transmembrane helix predicted for SEQ2059 by TMHMM2.0 at aa 27-49
553482009585	NAD+--asparagine ADP-ribosyltransferase [Signal transduction mechanisms]; Region: COG5585
553482009586	Phage Mu protein F like protein; Region: Phage_Mu_F; cl10072
553482009587	HMMPfam hit to PF04233, Phage Mu protein F like protein, score 7.2e-06
553482009588	Phage portal protein, SPP1 Gp6-like; Region: Phage_prot_Gp6; pfam05133
553482009589	phage portal protein, SPP1 family; Region: portal_SPP1; TIGR01538
553482009590	HMMPfam hit to PF05133, Phage portal protein, SPP1 Gp6-like, score 3.3e-59
553482009591	Phage terminase large subunit; Region: Terminase_3; cl12054
553482009592	Terminase-like family; Region: Terminase_6; pfam03237
553482009593	HMMPfam hit to PF04466, Phage terminase large subunit, score 8e-90
553482009594	HMMPfam hit to PF07570, Protein of unknown function (DUF1545), score 1.3e-21
553482009595	PS00017 ATP/GTP-binding site motif A (P-loop).
553482009596	Terminase small subunit; Region: Terminase_2; pfam03592
553482009597	HMMPfam hit to PF03592, Terminase small subunit, score 2.1e-53
553482009598	phage transcriptional activator, RinA family; Region: phage_rinA; TIGR01636
553482009599	Protein of unknown function (DUF1642); Region: DUF1642; pfam07852
553482009600	HMMPfam hit to PF07852, Protein of unknown function (DUF1642), score 8.4e-41
553482009601	SNF2 family N-terminal domain; Region: SNF2_N; pfam00176
553482009602	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
553482009603	ATP binding site [chemical binding]; other site
553482009604	putative Mg++ binding site [ion binding]; other site
553482009605	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cl17351
553482009606	nucleotide binding region [chemical binding]; other site
553482009607	ATP-binding site [chemical binding]; other site
553482009608	HMMPfam hit to PF00271, Helicase conserved C-terminal domain, score 0.015
553482009609	HMMPfam hit to PF00176, SNF2 family N-terminal domain, score 6.1e-07
553482009610	This model contains proteins with the VRR-NUC domain; Region: VRR_NUC; smart00990
553482009611	D5 N terminal like; Region: D5_N; smart00885
553482009612	phage/plasmid primase, P4 family, C-terminal domain; Region: primase_Cterm; TIGR01613
553482009613	Poxvirus D5 protein-like; Region: Pox_D5; pfam03288
553482009614	HMMPfam hit to PF03288, Poxvirus D5 protein-like, score 3.6e-133
553482009615	PS00017 ATP/GTP-binding site motif A (P-loop).
553482009616	Polymerase I functions primarily to fill DNA gaps that arise during DNA repair, recombination and replication; Region: DNA_pol_A_pol_I_A; cd08642
553482009617	active site
553482009618	DNA binding site [nucleotide binding]
553482009619	catalytic site [active]
553482009620	PS00447 DNA polymerase family A signature.
553482009621	Protein of unknown function (DUF2815); Region: DUF2815; pfam10991
553482009622	Protein of unknown function (DUF2800); Region: DUF2800; pfam10926
553482009623	PS00017 ATP/GTP-binding site motif A (P-loop).
553482009624	CDS contains a frameshift after codon 21 due to a 4 nucleotide deletion. Similar to Streptococcus pyogenes serotype M1 phage protein. UniProt:Q48X51 (EMBL:CP000017 (50 aa) fasta scores: E()=5.3e-17, 96.000% id in 50 aa
553482009625	PS00018 EF-hand calcium-binding domain.
553482009626	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cl17200
553482009627	Predicted helix-turn-helix motif with score 1346.000, SD 3.77 at aa 20-41, sequence IKKSDLAAAYGLNRQEVTNILS
553482009628	1 transmembrane helix predicted for SEQ2084 by TMHMM2.0 at aa 236-258
553482009629	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
553482009630	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
553482009631	non-specific DNA binding site [nucleotide binding]; other site
553482009632	salt bridge; other site
553482009633	sequence-specific DNA binding site [nucleotide binding]; other site
553482009634	HMMPfam hit to PF01381, Helix-turn-helix, score 1.7e-08
553482009635	Predicted helix-turn-helix motif with score 1133.000, SD 3.05 at aa 17-38, sequence ITLIQLEETLEYSRNTLYKLKT
553482009636	Domain of unknown function (DUF955); Region: DUF955; pfam06114
553482009637	HMMPfam hit to PF06114, Domain of unknown function (DUF955), score 1.8e-17
553482009638	PS00011 Vitamin K-dependent carboxylation domain.
553482009639	Integrase [DNA replication, recombination, and repair]; Region: XerC; COG0582
553482009640	Tn1545-related conjugative transposon integrases, site-specific recombinases, DNA breaking-rejoining enzymes, C-terminal catalytic domain. This CD includes bacterial (gram positive) and phage integrases, including those similar to Tn1545, Tn5252, and...; Region: INT_Tn1545_C; cd01199
553482009641	Int/Topo IB signature motif; other site
553482009642	HMMPfam hit to PF00589, Phage integrase family, score 2.5e-19
553482009643	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
553482009644	non-specific DNA binding site [nucleotide binding]; other site
553482009645	salt bridge; other site
553482009646	sequence-specific DNA binding site [nucleotide binding]; other site
553482009647	transcriptional activator, Rgg/GadR/MutR family, C-terminal domain; Region: RGG_Cterm; TIGR01716
553482009648	putative transposase OrfB; Reviewed; Region: PHA02517
553482009649	HTH-like domain; Region: HTH_21; pfam13276
553482009650	Integrase core domain; Region: rve; pfam00665
553482009651	Integrase core domain; Region: rve_2; pfam13333
553482009652	HMMPfam hit to PF00665, Integrase core domain, score 1.1e-37
553482009653	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
553482009654	Helix-turn-helix domain; Region: HTH_28; pfam13518
553482009655	HMMPfam hit to PF01527, Transposase, score 0.00062
553482009656	HMMPfam hit to PF02178, no description, score 0.21
553482009657	Predicted helix-turn-helix motif with score 1140.000, SD 3.07 at aa 19-40, sequence KSIKCLSEKFSIAESDLKYMIR
553482009658	CDS is truncated by the insertion of the upstream IS element and lacks an appropriate translational start site
553482009659	11 transmembrane helices predicted for SEQ2094 by TMHMM2.0 at aa 12-34, 44-63, 75-94, 98-120, 140-162, 172-194, 232-254, 264-286, 306-328, 353-375 and 380-402
553482009660	Transposase [DNA replication, recombination, and repair]; Region: COG5421
553482009661	Transposase [DNA replication, recombination, and repair]; Region: COG5421
553482009662	topology modulation protein; Provisional; Region: PRK07261
553482009663	AAA domain; Region: AAA_17; pfam13207
553482009664	PS00017 ATP/GTP-binding site motif A (P-loop).
553482009665	PS00290 Immunoglobulins and major histocompatibility complex proteins signature.
553482009666	1 transmembrane helix predicted for SEQ2098 by TMHMM2.0 at aa 6-28
553482009667	CDS contains a nonsense mutation (ochre) after codon 7
553482009668	1 transmembrane helix predicted for SEQ2099 by TMHMM2.0 at aa 5-27
553482009669	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
553482009670	HMMPfam hit to PF00746, Gram positive anchor, score 4.4e-11
553482009671	PS00343 Gram-positive cocci surface proteins 'anchoring' hexapeptide.
553482009672	Gram positive anchor; Region: Gram_pos_anchor; pfam00746
553482009673	HMMPfam hit to PF00746, Gram positive anchor, score 8.5e-10
553482009674	PS00343 Gram-positive cocci surface proteins 'anchoring' hexapeptide.
553482009675	HMMPfam hit to PF01391, Collagen triple helix repeat (20 copi, score 2.1e-11
553482009676	HMMPfam hit to PF01391, Collagen triple helix repeat (20 copi, score 8.6e-13
553482009677	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
553482009678	catalytic core [active]
553482009679	HMMPfam hit to PF00300, Phosphoglycerate mutase family, score 4.5e-34
553482009680	Microcin C7 self-immunity protein determines resistance to exogenous microcin C7; Region: Peptidase_S66_mccF_like; cd07062
553482009681	putative dimer interface [polypeptide binding]; other site
553482009682	catalytic triad [active]
553482009683	HMMPfam hit to PF02016, LD-carboxypeptidase, score 1.5e-39
553482009684	PS00308 Legume lectins alpha-chain signature.
553482009685	Glycerol dehydrogenase and related enzymes [Energy production and conversion]; Region: GldA; COG0371
553482009686	Glycerol dehydrogenases (GlyDH) catalyzes oxidation of glycerol to dihydroxyacetone in glycerol dissmilation; Region: GlyDH; cd08170
553482009687	dimer interface [polypeptide binding]; other site
553482009688	active site
553482009689	metal binding site [ion binding]; metal-binding site
553482009690	HMMPfam hit to PF00465, Iron-containing alcohol dehydrogenase, score 2.1e-78
553482009691	Transaldolase-like fructose-6-phosphate aldolases (FSA) found in bacteria and archaea; Region: Transaldolase_FSA; cd00956
553482009692	active site
553482009693	intersubunit interactions; other site
553482009694	catalytic residue [active]
553482009695	HMMPfam hit to PF00923, Transaldolase, score 9.1e-26
553482009696	PS00958 Transaldolase active site.
553482009697	Pyruvate-formate lyase [Energy production and conversion]; Region: PflD; COG1882
553482009698	Pyruvate formate lyase 2 and related enzymes; Region: PFL2_DhaB_BssA; cd01677
553482009699	dimer interface [polypeptide binding]; other site
553482009700	active site
553482009701	glycine loop; other site
553482009702	HMMPfam hit to PF01228, Glycine radical, score 3.2e-22
553482009703	PS00850 Glycine radical signature.
553482009704	HMMPfam hit to PF02901, Pyruvate formate lyase, score 2.6e-182
553482009705	PS00063 Aldo/keto reductase family active site signature.
553482009706	Phosphotransferase system cellobiose-specific component IIC [Carbohydrate transport and metabolism]; Region: CelB; COG1455
553482009707	cellobiose phosphotransferase system IIC component; Reviewed; Region: celD; PRK09592
553482009708	10 transmembrane helices predicted for SEQ2107 by TMHMM2.0 at aa 28-50, 70-92, 101-120, 135-157, 186-208, 223-245, 288-310, 347-369, 374-396 and 400-417
553482009709	HMMPfam hit to PF02378, Phosphotransferase system, EIIC, score 4.5e-103
553482009710	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482009711	PTS_IIB_chitobiose_lichenan: subunit IIB of enzyme II (EII) of the N,N-diacetylchitobiose-specific and lichenan-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In these systems, EII is either a lichenan- or an N; Region: PTS_IIB_chitobiose_lichenan; cd05564
553482009712	active site
553482009713	P-loop; other site
553482009714	phosphorylation site [posttranslational modification]
553482009715	HMMPfam hit to PF02302, PTS system, Lactose/Cellobiose specific IIB, score 2.5e-40
553482009716	PTS_IIA, PTS system, lactose/cellobiose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_lac; cd00215
553482009717	active site
553482009718	methionine cluster; other site
553482009719	phosphorylation site [posttranslational modification]
553482009720	metal binding site [ion binding]; metal-binding site
553482009721	HMMPfam hit to PF02255, PTS system, Lactose/Cellobiose specific IIA, score 1.4e-33
553482009722	Transcriptional regulator, contains sigma factor-related N-terminal domain [Transcription]; Region: DeoR; COG2390
553482009723	Helix-turn-helix domain; Region: HTH_28; pfam13518
553482009724	Putative sugar-binding domain; Region: Sugar-bind; pfam04198
553482009725	HMMPfam hit to PF04198, sugar-binding domain, score 3.3e-96
553482009726	Predicted helix-turn-helix motif with score 1610.000, SD 4.67 at aa 21-42, sequence KSQTAISKQMNIYRTTVCRMLA
553482009727	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
553482009728	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
553482009729	DNA-binding site [nucleotide binding]; DNA binding site
553482009730	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
553482009731	HMMPfam hit to PF00455, Bacterial regulatory proteins, deoR family, score 3.3e-35
553482009732	HMMPfam hit to PF08220, DeoR-like helix-turn-helix domain, score 3.6e-19
553482009733	HMMPfam hit to PF08279, HTH domain, score 3.7e-07
553482009734	PS00894 Bacterial regulatory proteins, deoR family signature.
553482009735	glycyl-radical enzyme activating protein family; Region: PFLE_PFLC; TIGR02494
553482009736	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
553482009737	FeS/SAM binding site; other site
553482009738	PS00473 Gonadotropin-releasing hormones signature.
553482009739	PS01087 Radical activating enzymes signature.
553482009740	Adenylosuccinate synthetase; Region: Adenylsucc_synt; smart00788
553482009741	Adenylosuccinate synthetase (AdSS) catalyzes the first step in the de novo biosynthesis of AMP. IMP and L-aspartate are conjugated in a two-step reaction accompanied by the hydrolysis of GTP to GDP in the presence of Mg2+. In the first step, the...; Region: AdSS; cd03108
553482009742	GDP-binding site [chemical binding]; other site
553482009743	ACT binding site; other site
553482009744	IMP binding site; other site
553482009745	HMMPfam hit to PF00709, Adenylosuccinate synthetase, score 6.4e-304
553482009746	PS00513 Adenylosuccinate synthetase active site.
553482009747	PS01266 Adenylosuccinate synthetase GTP-binding site.
553482009748	2 transmembrane helices predicted for SEQ2114 by TMHMM2.0 at aa 13-32 and 37-54
553482009749	Uncharacterized protein involved in tellurite resistance [Inorganic ion transport and metabolism]; Region: TelA; COG3853
553482009750	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
553482009751	Helix-turn-helix domain; Region: HTH_28; pfam13518
553482009752	Predicted helix-turn-helix motif with score 1140.000, SD 3.07 at aa 19-40, sequence KSIKCLSEKFSIAESDLKYMIR
553482009753	HMMPfam hit to PF01527, Transposase, score 0.00062
553482009754	HMMPfam hit to PF02178, no description, score 0.21
553482009756	CDS is truncated by the insertion of the upstream IS element and subsequent deletion events. CDS lacks appropriate translational start site. Similar to Streptococcus agalactiae transcriptional regulator, AraC family UniProt:Q3DB93 (EMBL:AAJR01000002 (402 aa) fasta scores: E()=2e-86, 60.825% id in 388 aa
553482009757	HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix protei, score 6.4e-05
553482009758	Predicted helix-turn-helix motif with score 1451.000, SD 4.13 at aa 310-331, sequence LKVSDIAKHLYISESHLRAVFK
553482009759	Hsp33-like chaperonin; Reviewed; Region: hslO; PRK00114
553482009760	Heat shock protein 33 (Hsp33):  Cytosolic protein that acts as a molecular chaperone under oxidative conditions.  In normal (reducing) cytosolic conditions, four conserved Cys residues are coordinated by a Zn ion. Under oxidative stress (such as heat...; Region: Hsp33; cd00498
553482009761	dimerization interface [polypeptide binding]; other site
553482009762	domain crossover interface; other site
553482009763	redox-dependent activation switch; other site
553482009764	HMMPfam hit to PF01430, Hsp33 protein, score 1.4e-151
553482009765	putative TIM-barrel protein, nifR3 family; Region: nifR3_yhdG; TIGR00737
553482009766	Dihydrouridine synthase-like (DUS-like) FMN-binding domain. Members of this family catalyze the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also...; Region: DUS_like_FMN; cd02801
553482009767	FMN binding site [chemical binding]; other site
553482009768	active site
553482009769	catalytic residues [active]
553482009770	substrate binding site [chemical binding]; other site
553482009771	HMMPfam hit to PF00724, NADH:flavin oxidoreductase / NADH oxidas, score 0.00052
553482009772	HMMPfam hit to PF01180, Dihydroorotate dehydrogenase, score 0.043
553482009773	HMMPfam hit to PF01207, Dihydrouridine synthase (Dus), score 2.1e-102
553482009774	PS01136 Uncharacterized protein family UPF0034 signature.
553482009775	CDS contains a nonsense mutation (ochre) after codon 119. Similar to Streptococcus pyogenes serotype M1 deoxyguanosine kinase/deoxyadenosine kinase(i) subunit (deoxyadenosine kinase/deoxyguanosine kinase. UniProt:Q9A1S5 (EMBL:AE006482 (213 aa) fasta scores: E()=7.5e-65, 90.610% id in 213 aa
553482009776	PS00017 ATP/GTP-binding site motif A (P-loop).
553482009777	ABC-type uncharacterized transport system, ATPase component [General function prediction only]; Region: PhnK; COG1101
553482009778	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
553482009779	Walker A/P-loop; other site
553482009780	ATP binding site [chemical binding]; other site
553482009781	Q-loop/lid; other site
553482009782	ABC transporter signature motif; other site
553482009783	Walker B; other site
553482009784	D-loop; other site
553482009785	H-loop/switch region; other site
553482009786	HMMPfam hit to PF00005, ABC transporter, score 1.4e-40
553482009787	PS00211 ABC transporters family signature.
553482009788	PS00017 ATP/GTP-binding site motif A (P-loop).
553482009789	Transmembrane subunit (TM) of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which are involved in the uptake of branched-chain amino acids (AAs), as well as TMs of transporters involved in the uptake of...; Region: TM_PBP1_branched-chain-AA_like; cd06574
553482009790	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
553482009791	TM-ABC transporter signature motif; other site
553482009792	7 transmembrane helices predicted for SEQ2126 by TMHMM2.0 at aa 10-28, 41-63, 83-105, 129-151, 209-228, 235-257 and 267-282
553482009793	HMMPfam hit to PF02653, Branched-chain amino acid transport syst, score 1.1e-21
553482009794	Type I periplasmic ligand-binding domain of uncharacterized ABC-type transport systems that are predicted to be involved in the uptake of amino acids, peptides, or inorganic ions; Region: PBP1_ABC_uncharacterized_transporter; cd06325
553482009795	Periplasmic binding protein domain; Region: Peripla_BP_4; pfam13407
553482009796	zinc binding site [ion binding]; other site
553482009797	putative ligand binding site [chemical binding]; other site
553482009798	HMMPfam hit to PF04392, ABC transporter substrate binding protei, score 4.5e-81
553482009799	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482009800	Type I periplasmic ligand-binding domain of uncharacterized ABC-type transport systems that are predicted to be involved in the uptake of amino acids, peptides, or inorganic ions; Region: PBP1_ABC_uncharacterized_transporter; cd06325
553482009801	Periplasmic binding protein domain; Region: Peripla_BP_4; pfam13407
553482009802	zinc binding site [ion binding]; other site
553482009803	putative ligand binding site [chemical binding]; other site
553482009804	HMMPfam hit to PF04392, ABC transporter substrate binding protei, score 5.4e-73
553482009805	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482009806	Single-stranded DNA-binding protein [DNA replication, recombination, and repair]; Region: Ssb; COG0629
553482009807	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
553482009808	dimer interface [polypeptide binding]; other site
553482009809	ssDNA binding site [nucleotide binding]; other site
553482009810	tetramer (dimer of dimers) interface [polypeptide binding]; other site
553482009811	HMMPfam hit to PF00436, Single-strand binding protein family, score 1.3e-23
553482009812	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
553482009813	S-adenosylmethionine binding site [chemical binding]; other site
553482009814	HMMPfam hit to PF08241, Methyltransferase domain, score 8.8e-15
553482009815	HMMPfam hit to PF08242, Methyltransferase domain, score 2e-11
553482009816	tRNA-binding-domain-containing prokaryotic phenylalanly tRNA synthetase (PheRS) beta chain.  PheRS aminoacylate phenylalanine transfer RNAs (tRNAphe). PheRSs belong structurally to class II aminoacyl tRNA synthetases (aaRSs) but, as they aminoacylate...; Region: tRNA_bind_bactPheRS; cd02796
553482009817	putative tRNA-binding site [nucleotide binding]; other site
553482009818	HMMPfam hit to PF01588, tRNA binding domain, score 9.2e-18
553482009819	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
553482009820	catalytic residues [active]
553482009821	HMMPfam hit to PF00085, Thioredoxin, score 2.7e-05
553482009822	Cellulase M and related proteins [Carbohydrate transport and metabolism]; Region: FrvX; COG1363
553482009823	glutamyl aminopeptidase; Region: glu_aminopep; TIGR03107
553482009824	PS00402 Binding-protein-dependent transport systems inner membrane comp. sign.
553482009825	HMMPfam hit to PF05343, M42 glutamyl aminopeptidase, score 1.6e-133
553482009826	NADP oxidoreductase coenzyme F420-dependent; Region: F420_oxidored; cl17232
553482009827	pyrroline-5-carboxylate reductase; Reviewed; Region: PRK11880
553482009828	HMMPfam hit to PF01210, NAD-dependent glycerol-3-phosphate deh, score 0.003
553482009829	HMMPfam hit to PF03807, NADP oxidoreductase coenzyme F420-depe, score 2.4e-51
553482009830	PS00521 Delta 1-pyrroline-5-carboxylate reductase signature.
553482009831	4 transmembrane helices predicted for SEQ2136 by TMHMM2.0 at aa 21-43, 47-69, 96-118 and 122-141
553482009832	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482009833	CAAX protease self-immunity; Region: Abi; pfam02517
553482009834	7 transmembrane helices predicted for SEQ2137 by TMHMM2.0 at aa 17-36, 46-68, 81-103, 116-138, 151-173, 177-194 and 201-223
553482009835	HMMPfam hit to PF02517, CAAX amino terminal protease family, score 5.8e-18
553482009836	CDS contains a frameshift after codon 69. Similar to Streptococcus mutans hypothetical protein UniProt:Q8DS59 (EMBL:AE014133 (146 aa) fasta scores: E()=2.9e-13, 36.429% id in 140 aa
553482009837	2 transmembrane helices predicted for SEQ2138 by TMHMM2.0 at aa 33-55 and 59-81
553482009838	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482009839	2 transmembrane helices predicted for SEQ2139 by TMHMM2.0 at aa 21-43 and 47-69
553482009840	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
553482009841	non-specific DNA binding site [nucleotide binding]; other site
553482009842	salt bridge; other site
553482009843	sequence-specific DNA binding site [nucleotide binding]; other site
553482009844	HMMPfam hit to PF01381, Helix-turn-helix, score 6.9e-17
553482009845	Predicted helix-turn-helix motif with score 2084.000, SD 6.28 at aa 14-35, sequence ISQADLADMMCVTRQTIISLEK
553482009846	hypothetical protein; Validated; Region: PRK02101
553482009847	HMMPfam hit to PF03883, Protein of unknown function (DUF328), score 3.3e-85
553482009848	4Fe-4S single cluster domain; Region: Fer4_12; pfam13353
553482009849	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
553482009850	FeS/SAM binding site; other site
553482009851	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
553482009852	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
553482009853	Coenzyme A binding pocket [chemical binding]; other site
553482009854	HMMPfam hit to PF00583, Acetyltransferase (GNAT) family, score 4.4e-11
553482009855	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
553482009856	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
553482009857	HMMPfam hit to PF01408, Oxidoreductase family, NAD-binding Rossm, score 4.5e-14
553482009858	anaerobic ribonucleoside triphosphate reductase; Provisional; Region: PRK09263
553482009859	ATP cone domain; Region: ATP-cone; pfam03477
553482009860	Class III ribonucleotide reductase; Region: RNR_III; cd01675
553482009861	effector binding site; other site
553482009862	active site
553482009863	Zn binding site [ion binding]; other site
553482009864	glycine loop; other site
553482009865	HMMPfam hit to PF01228, Glycine radical, score 2.8e-30
553482009866	PS00850 Glycine radical signature.
553482009867	HMMPfam hit to PF03477, ATP cone domain, score 5.5e-29
553482009868	Predicted membrane protein (DUF2079); Region: DUF2079; pfam09852
553482009869	11 transmembrane helices predicted for SEQ2147 by TMHMM2.0 at aa 35-57, 90-112, 125-147, 152-174, 186-200, 204-221, 228-250, 276-298, 311-330, 340-362 and 382-404
553482009870	PS00133 Zinc carboxypeptidases, zinc-binding region 2 signature.
553482009871	hypothetical protein; Provisional; Region: PRK13678
553482009872	HMMPfam hit to PF06949, Protein of unknown function (DUF1292), score 4.3e-55
553482009873	Holliday junction resolvase-like protein; Reviewed; Region: PRK00109
553482009874	HMMPfam hit to PF03652, Uncharacterised protein family (UPF0081), score 2.2e-51
553482009875	hypothetical protein; Provisional; Region: PRK05473
553482009876	HMMPfam hit to PF06135, Bacterial protein of unknown function (DUF96, score 4.8e-51
553482009877	Arsenate Reductase (ArsC) family, Spx subfamily; Spx is a unique RNA polymerase (RNAP)-binding protein present in bacilli and some mollicutes. It inhibits transcription by binding to the C-terminal domain of the alpha subunit of RNAP, disrupting complex...; Region: ArsC_Spx; cd03032
553482009878	ArsC family; Region: ArsC; pfam03960
553482009879	putative catalytic residues [active]
553482009880	thiol/disulfide switch; other site
553482009881	HMMPfam hit to PF03960, ArsC family, score 1.5e-53
553482009882	recombinase A; Provisional; Region: recA; PRK09354
553482009883	RecA is a  bacterial enzyme which has roles in homologous recombination, DNA repair, and the induction of the SOS response.  RecA couples ATP hydrolysis to DNA strand exchange; Region: recA; cd00983
553482009884	hexamer interface [polypeptide binding]; other site
553482009885	Walker A motif; other site
553482009886	ATP binding site [chemical binding]; other site
553482009887	Walker B motif; other site
553482009888	HMMPfam hit to PF00154, recA bacterial DNA recombination protein, score 2.3e-234
553482009889	PS00321 recA signature.
553482009890	PS00017 ATP/GTP-binding site motif A (P-loop).
553482009891	competence damage-inducible protein A; Provisional; Region: PRK00549
553482009892	Competence-damaged protein. CinA is the first gene in the competence- inducible (cin) operon and is thought to be specifically required at some stage in the process of transformation. This domain is closely related to a domain, found in a variety of...; Region: cinA; cd00885
553482009893	putative MPT binding site; other site
553482009894	Uncharacterized protein (competence- and mitomycin-induced) [General function prediction only]; Region: CinA; COG1546
553482009895	HMMPfam hit to PF02464, Competence-damaged protein, score 2.7e-64
553482009896	HMMPfam hit to PF00994, molybdopterin binding domain, score 5.3e-47
553482009897	3 transmembrane helices predicted for SEQ2154 by TMHMM2.0 at aa 7-29, 39-61 and 68-90
553482009898	PLA2_like: Phospholipase A2, a super-family of secretory and cytosolic enzymes; the latter are either Ca dependent or Ca independent. PLA2 cleaves the sn-2 position of the glycerol backbone of phospholipids (PC or phosphatidylethanolamine), usually in a...; Region: PLA2_like; cl05417
553482009899	primary metal binding site; other site
553482009900	catalytic residues [active]
553482009901	1 transmembrane helix predicted for SEQ2155 by TMHMM2.0 at aa 13-35
553482009902	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
553482009903	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
553482009904	non-specific DNA binding site [nucleotide binding]; other site
553482009905	salt bridge; other site
553482009906	sequence-specific DNA binding site [nucleotide binding]; other site
553482009907	HMMPfam hit to PF01381, Helix-turn-helix, score 2.9e-06
553482009908	Methyladenine glycosylase; Region: Adenine_glyco; pfam03352
553482009909	HMMPfam hit to PF03352, Methyladenine glycosylase, score 3.7e-88
553482009910	Holliday junction DNA helicase RuvA; Reviewed; Region: ruvA; PRK00116
553482009911	RuvA N terminal domain; Region: RuvA_N; pfam01330
553482009912	RuvA, C-terminal domain; Region: RuvA_C; pfam07499
553482009913	HMMPfam hit to PF07499, RuvA, C-terminal domain, score 5.8e-17
553482009914	HMMPfam hit to PF01330, RuvA N terminal domain, score 9.8e-26
553482009915	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
553482009916	Major Facilitator Superfamily; Region: MFS_1; pfam07690
553482009917	putative substrate translocation pore; other site
553482009918	12 transmembrane helices predicted for SEQ2159 by TMHMM2.0 at aa 16-35, 40-62, 75-93, 98-120, 141-160, 165-187, 218-236, 256-278, 291-310, 314-336, 349-371 and 381-400
553482009919	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482009920	PS00216 Sugar transport proteins signature 1.
553482009921	DNA mismatch repair protein; Reviewed; Region: mutL; PRK00095
553482009922	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
553482009923	ATP binding site [chemical binding]; other site
553482009924	Mg2+ binding site [ion binding]; other site
553482009925	G-X-G motif; other site
553482009926	MutL_Trans: transducer domain, having a ribosomal S5 domain 2-like fold, conserved in the C-terminal domain of DNA mismatch repair (MutL/MLH1/PMS2) family. This transducer domain is homologous to the second domain of the DNA gyrase B subunit, which is...; Region: MutL_Trans; cd00782
553482009927	ATP binding site [chemical binding]; other site
553482009928	MutL C terminal dimerisation domain; Region: MutL_C; pfam08676
553482009929	HMMPfam hit to PF01119, DNA mismatch repair protein, C-termina, score 1e-40
553482009930	HMMPfam hit to PF02518, Histidine kinase-, DNA gyrase B-, and, score 2.6e-06
553482009931	PS00058 DNA mismatch repair proteins mutL / hexB / PMS1 signature.
553482009932	DNA mismatch repair protein MutS; Provisional; Region: PRK05399
553482009933	MutS domain I; Region: MutS_I; pfam01624
553482009934	MutS domain II; Region: MutS_II; pfam05188
553482009935	MutS domain III; Region: MutS_III; pfam05192
553482009936	MutS domain V; Region: MutS_V; pfam00488
553482009937	Walker A/P-loop; other site
553482009938	ATP binding site [chemical binding]; other site
553482009939	Q-loop/lid; other site
553482009940	ABC transporter signature motif; other site
553482009941	Walker B; other site
553482009942	D-loop; other site
553482009943	H-loop/switch region; other site
553482009944	HMMPfam hit to PF00488, MutS domain V, score 2.6e-151
553482009945	PS00486 DNA mismatch repair proteins mutS family signature.
553482009946	PS00017 ATP/GTP-binding site motif A (P-loop).
553482009947	HMMPfam hit to PF05192, MutS domain III, score 1.1e-93
553482009948	HMMPfam hit to PF05190, MutS family domain IV, score 2.3e-37
553482009949	HMMPfam hit to PF05188, MutS domain II, score 5.2e-28
553482009950	HMMPfam hit to PF01624, MutS domain I, score 1.6e-70
553482009951	Protein of unknown function (DUF964); Region: DUF964; cl01483
553482009952	Arginine repressor, DNA binding domain; Region: Arg_repressor; pfam01316
553482009953	arginine repressor; Region: argR_whole; TIGR01529
553482009954	Arginine repressor, C-terminal domain; Region: Arg_repressor_C; pfam02863
553482009955	HMMPfam hit to PF02863, Arginine repressor, C-terminal domain, score 1.1e-24
553482009956	HMMPfam hit to PF01316, Arginine repressor, DNA binding domai, score 1.1e-24
553482009957	arginyl-tRNA synthetase; Reviewed; Region: PRK12451
553482009958	Arginyl tRNA synthetase N terminal dom; Region: Arg_tRNA_synt_N; smart01016
553482009959	catalytic core domain of arginyl-tRNA synthetases; Region: ArgRS_core; cd00671
553482009960	active site
553482009961	HIGH motif; other site
553482009962	KMSK motif region; other site
553482009963	Anticodon-binding domain of arginyl tRNA synthetases; Region: Anticodon_Ia_Arg; cd07956
553482009964	tRNA binding surface [nucleotide binding]; other site
553482009965	anticodon binding site; other site
553482009966	HMMPfam hit to PF03485, Arginyl tRNA synthetase N terminal do, score 1.9e-29
553482009967	HMMPfam hit to PF00750, tRNA synthetases class I (R), score 4.3e-101
553482009968	HMMPfam hit to PF05746, DALR anticodon binding domain, score 7e-50
553482009969	ABC-type uncharacterized transport system, ATPase component [General function prediction only]; Region: COG4619
553482009970	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
553482009971	ABC transporter; Region: ABC_tran_2; pfam12848
553482009972	ABC-type molybdenum transport system, ATPase component/photorepair protein PhrA [Inorganic ion transport and metabolism]; Region: ModF; COG1119
553482009973	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
553482009974	HMMPfam hit to PF00005, ABC transporter, score 3.9e-25
553482009975	PS00211 ABC transporters family signature.
553482009976	PS00017 ATP/GTP-binding site motif A (P-loop).
553482009977	HMMPfam hit to PF00005, ABC transporter, score 2.7e-20
553482009978	PS00017 ATP/GTP-binding site motif A (P-loop).
553482009979	Uncharacterized conserved protein [Function unknown]; Region: COG1284
553482009980	Uncharacterized BCR, YitT family COG1284; Region: DUF161; pfam02588
553482009981	Uncharacterized BCR, YitT family COG1284; Region: DUF161; pfam02588
553482009982	Uncharacterized protein conserved in bacteria (DUF2179); Region: DUF2179; pfam10035
553482009983	6 transmembrane helices predicted for SEQ2166 by TMHMM2.0 at aa 13-30, 40-62, 74-96, 111-133, 153-172 and 177-199
553482009984	HMMPfam hit to PF02588, Uncharacterized BCR, YitT family COG1284, score 1.3e-22
553482009985	HMMPfam hit to PF02588, Uncharacterized BCR, YitT family COG1284, score 4.9e-25
553482009986	Uncharacterized conserved protein [Function unknown]; Region: COG1284
553482009987	Uncharacterized BCR, YitT family COG1284; Region: DUF161; pfam02588
553482009988	Uncharacterized BCR, YitT family COG1284; Region: DUF161; pfam02588
553482009989	Uncharacterized protein conserved in bacteria (DUF2179); Region: DUF2179; pfam10035
553482009990	HMMPfam hit to PF02588, Uncharacterized BCR, YitT family COG1284, score 1.8e-17
553482009991	5 transmembrane helices predicted for SEQ2167 by TMHMM2.0 at aa 12-34, 49-71, 78-95, 110-132 and 156-178
553482009992	HMMPfam hit to PF02588, Uncharacterized BCR, YitT family COG1284, score 6.4e-20
553482009993	Uncharacterized conserved protein [Function unknown]; Region: COG1284
553482009994	Uncharacterized BCR, YitT family COG1284; Region: DUF161; pfam02588
553482009995	Uncharacterized BCR, YitT family COG1284; Region: DUF161; pfam02588
553482009996	Uncharacterized protein conserved in bacteria (DUF2179); Region: DUF2179; pfam10035
553482009997	HMMPfam hit to PF02588, Uncharacterized BCR, YitT family COG1284, score 3.6e-26
553482009998	5 transmembrane helices predicted for SEQ2168 by TMHMM2.0 at aa 41-63, 83-105, 112-130, 140-162 and 183-205
553482009999	HMMPfam hit to PF02588, Uncharacterized BCR, YitT family COG1284, score 1.8e-23
553482010000	aspartyl-tRNA synthetase; Validated; Region: aspS; PRK00476
553482010001	EcAspRS_like_N: N-terminal, anticodon recognition domain of the type found in Escherichia coli aspartyl-tRNA synthetase (AspRS), the human mitochondrial (mt) AspRS-2, the discriminating (D) Thermus thermophilus AspRS-1, and the nondiscriminating (ND)...; Region: EcAspRS_like_N; cd04317
553482010002	dimer interface [polypeptide binding]; other site
553482010003	anticodon binding site; other site
553482010004	Asp tRNA synthetase (aspRS) class II core domain. Class II assignment is based upon its structure and the presence of three characteristic sequence motifs. AspRS is a homodimer, which attaches a specific amino acid to the 3' OH group of ribose of...; Region: AspRS_core; cd00777
553482010005	homodimer interface [polypeptide binding]; other site
553482010006	motif 1; other site
553482010007	active site
553482010008	motif 2; other site
553482010009	GAD domain; Region: GAD; pfam02938
553482010010	Asp tRNA synthetase (aspRS) class II core domain. Class II assignment is based upon its structure and the presence of three characteristic sequence motifs. AspRS is a homodimer, which attaches a specific amino acid to the 3' OH group of ribose of...; Region: AspRS_core; cd00777
553482010011	motif 3; other site
553482010012	HMMPfam hit to PF00152, tRNA synthetases class II (D, K and N), score 2.8e-216
553482010013	PS00339 Aminoacyl-transfer RNA synthetases class-II signature 2.
553482010014	HMMPfam hit to PF02938, GAD domain, score 2.2e-33
553482010015	PS00179 Aminoacyl-transfer RNA synthetases class-II signature 1.
553482010016	HMMPfam hit to PF01336, OB-fold nucleic acid binding domain, score 4.5e-23
553482010017	ABC-2 type transporter; Region: ABC2_membrane; cl17235
553482010018	6 transmembrane helices predicted for SEQ2170 by TMHMM2.0 at aa 25-47, 57-79, 100-122, 137-159, 166-185 and 219-241
553482010019	HMMPfam hit to PF01061, ABC-2 type transporter, score 0.00031
553482010020	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
553482010021	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
553482010022	Walker A/P-loop; other site
553482010023	ATP binding site [chemical binding]; other site
553482010024	Q-loop/lid; other site
553482010025	ABC transporter signature motif; other site
553482010026	Walker B; other site
553482010027	D-loop; other site
553482010028	H-loop/switch region; other site
553482010029	HMMPfam hit to PF00005, ABC transporter, score 4.3e-38
553482010030	PS00017 ATP/GTP-binding site motif A (P-loop).
553482010031	Response regulator of the LytR/AlgR family [Transcription / Signal transduction mechanisms]; Region: LytT; COG3279
553482010032	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
553482010033	active site
553482010034	phosphorylation site [posttranslational modification]
553482010035	intermolecular recognition site; other site
553482010036	dimerization interface [polypeptide binding]; other site
553482010037	LytTr DNA-binding domain; Region: LytTR; smart00850
553482010038	HMMPfam hit to PF00072, Response regulator receiver domain, score 2.2e-10
553482010039	HMMPfam hit to PF04397, LytTr DNA-binding domain, score 2.9e-15
553482010040	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Region: HATPase_c; pfam02518
553482010041	Mg2+ binding site [ion binding]; other site
553482010042	G-X-G motif; other site
553482010043	7 transmembrane helices predicted for SEQ2173 by TMHMM2.0 at aa 5-23, 36-53, 57-79, 86-108, 118-137, 157-179 and 189-211
553482010044	histidyl-tRNA synthetase; Reviewed; Region: hisS; PRK00037
553482010045	Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core domain. HisRS is a homodimer. It is responsible for the attachment of histidine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for...; Region: HisRS-like_core; cd00773
553482010046	dimer interface [polypeptide binding]; other site
553482010047	motif 1; other site
553482010048	active site
553482010049	motif 2; other site
553482010050	HisRS Histidyl-anticodon binding domain. HisRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: HisRS_anticodon; cd00859
553482010051	anticodon binding site; other site
553482010052	HMMPfam hit to PF03129, Anticodon binding domain, score 9.2e-16
553482010053	PS00339 Aminoacyl-transfer RNA synthetases class-II signature 2.
553482010054	HMMPfam hit to PF00587, tRNA synthetase class II core domain (, score 2.9e-57
553482010055	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482010056	50S ribosomal protein L32; Validated; Region: rpmF; PRK01110
553482010057	HMMPfam hit to PF01783, Ribosomal L32p protein family, score 8.2e-21
553482010058	50S ribosomal protein L33; Validated; Region: rpmG; PRK00595
553482010059	HMMPfam hit to PF00471, Ribosomal protein L33, score 1e-17
553482010060	Protein of unknown function (DUF4065); Region: DUF4065; pfam13274
553482010061	RelA- and SpoT-like ppGpp Synthetases and Hydrolases, catalytic domain; Region: Rel-Spo_like; cl11966
553482010062	metal binding triad [ion binding]; metal-binding site
553482010063	Chromosome segregation ATPases [Cell division and chromosome partitioning]; Region: Smc; COG1196
553482010064	HMMPfam hit to PF00746, Gram positive anchor, score 3.1e-05
553482010065	PS00343 Gram-positive cocci surface proteins 'anchoring' hexapeptide.
553482010066	1 transmembrane helix predicted for SEQ2180 by TMHMM2.0 at aa 594-616
553482010067	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482010068	protein binding site [polypeptide binding]; other site
553482010069	Domain present in PSD-95, Dlg, and ZO-1/2; Region: PDZ; smart00228
553482010070	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: COG4585
553482010071	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Region: HATPase_c; pfam02518
553482010072	9 transmembrane helices predicted for SEQ2181 by TMHMM2.0 at aa 21-43, 124-143, 155-177, 181-203, 216-238, 243-265, 278-297, 301-323 and 335-357
553482010073	PS00038 Myc-type, 'helix-loop-helix' dimerization domain signature.
553482010074	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
553482010075	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
553482010076	active site
553482010077	phosphorylation site [posttranslational modification]
553482010078	intermolecular recognition site; other site
553482010079	dimerization interface [polypeptide binding]; other site
553482010080	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
553482010081	DNA binding residues [nucleotide binding]
553482010082	dimerization interface [polypeptide binding]; other site
553482010083	HMMPfam hit to PF00072, Response regulator receiver domain, score 2.1e-18
553482010084	HMMPfam hit to PF00196, Bacterial regulatory proteins, luxR fami, score 7.2e-14
553482010085	Predicted helix-turn-helix motif with score 1093.000, SD 2.91 at aa 154-175, sequence YSNEKISKKLYISRRTVDTHVS
553482010086	Pseudomonas avirulence D protein (AvrD); Region: AvrD; pfam05655
553482010087	HMMPfam hit to PF05655, Pseudomonas avirulence D protein (AvrD), score 1.2e-09
553482010088	PS00017 ATP/GTP-binding site motif A (P-loop).
553482010089	putative transposase OrfB; Reviewed; Region: PHA02517
553482010090	HTH-like domain; Region: HTH_21; pfam13276
553482010091	Integrase core domain; Region: rve; pfam00665
553482010092	Integrase core domain; Region: rve_2; pfam13333
553482010093	HMMPfam hit to PF00665, Integrase core domain, score 4.8e-37
553482010094	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
553482010095	Transposase; Region: HTH_Tnp_1; cl17663
553482010096	HMMPfam hit to PF01527, Transposase, score 0.00051
553482010097	PS00017 ATP/GTP-binding site motif A (P-loop).
553482010098	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
553482010099	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
553482010100	Walker A/P-loop; other site
553482010101	ATP binding site [chemical binding]; other site
553482010102	Q-loop/lid; other site
553482010103	ABC transporter signature motif; other site
553482010104	Walker B; other site
553482010105	D-loop; other site
553482010106	H-loop/switch region; other site
553482010107	HMMPfam hit to PF00005, ABC transporter, score 4.6e-61
553482010108	PS00017 ATP/GTP-binding site motif A (P-loop).
553482010109	PS00211 ABC transporters family signature.
553482010110	ABC-type transport system, involved in lipoprotein release, permease component [Cell envelope biogenesis, outer membrane]; Region: LolE; COG4591
553482010111	FtsX-like permease family; Region: FtsX; pfam02687
553482010112	ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms]; Region: SalY; COG0577
553482010113	ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms]; Region: SalY; COG0577
553482010114	FtsX-like permease family; Region: FtsX; pfam02687
553482010115	8 transmembrane helices predicted for SEQ2189 by TMHMM2.0 at aa 32-54, 273-295, 315-337, 360-382, 437-459, 641-663, 690-712 and 732-754
553482010116	HMMPfam hit to PF02687, Predicted permease, score 8.3e-21
553482010117	HMMPfam hit to PF02687, Predicted permease, score 6.7e-16
553482010118	Gram positive anchor; Region: Gram_pos_anchor; pfam00746
553482010119	2 transmembrane helices predicted for SEQ2190 by TMHMM2.0 at aa 21-38 and 641-663
553482010120	HMMPfam hit to PF00746, Gram positive anchor, score 5.8e-06
553482010121	PS00343 Gram-positive cocci surface proteins 'anchoring' hexapeptide.
553482010122	Predicted membrane protein [Function unknown]; Region: COG2035
553482010123	HMMPfam hit to PF04018, Domain of unknown function (DUF368), score 1e-107
553482010124	8 transmembrane helices predicted for SEQ2191 by TMHMM2.0 at aa 13-35, 48-70, 80-102, 115-137, 152-174, 186-204, 219-236 and 249-271
553482010125	HMMPfam hit to PF00293, NUDIX domain, score 1.4e-07
553482010126	PS00893 mutT domain signature.
553482010127	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
553482010128	Helix-turn-helix domain; Region: HTH_28; pfam13518
553482010129	Predicted helix-turn-helix motif with score 1140.000, SD 3.07 at aa 19-40, sequence KSIKCLSEKFSIAESDLKYMIR
553482010130	HMMPfam hit to PF01527, Transposase, score 0.00062
553482010131	HMMPfam hit to PF02178, no description, score 0.21
553482010132	putative transposase OrfB; Reviewed; Region: PHA02517
553482010133	HTH-like domain; Region: HTH_21; pfam13276
553482010134	Integrase core domain; Region: rve; pfam00665
553482010135	Integrase core domain; Region: rve_2; pfam13333
553482010136	HMMPfam hit to PF00665, Integrase core domain, score 1.1e-37
553482010137	Predicted transcriptional regulators [Transcription]; Region: COG1695
553482010138	Transcriptional regulator PadR-like family; Region: PadR; pfam03551
553482010139	HMMPfam hit to PF03551, Transcriptional regulator PadR-like family, score 1.9e-18
553482010140	Predicted membrane protein [Function unknown]; Region: COG4709
553482010141	Predicted membrane protein [Function unknown]; Region: COG4709
553482010142	Domain of unknown function (DUF4097); Region: DUF4097; pfam13349
553482010143	Domain of unknown function (DUF4098); Region: DUF4098; pfam13345
553482010144	Predicted membrane protein [Function unknown]; Region: COG1511
553482010145	YhgE/Pip N-terminal domain; Region: pip_yhgE_Nterm; TIGR03061
553482010146	YhgE/Pip C-terminal domain; Region: pip_yhgE_Cterm; TIGR03062
553482010147	6 transmembrane helices predicted for SEQ2199 by TMHMM2.0 at aa 13-35, 577-599, 619-641, 651-670, 675-697 and 730-752
553482010148	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
553482010149	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
553482010150	HMMPfam hit to PF00440, Bacterial regulatory proteins, tetR family, score 1.6e-05
553482010151	Predicted helix-turn-helix motif with score 1376.000, SD 3.87 at aa 28-49, sequence VTTVQLAKMAGISRSSFYTHYK
553482010152	30S ribosomal protein S4; Validated; Region: rpsD; PRK05327
553482010153	Ribosomal protein S4/S9 N-terminal domain; Region: Ribosomal_S4; pfam00163
553482010154	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
553482010155	RNA binding surface [nucleotide binding]; other site
553482010156	HMMPfam hit to PF01479, S4 domain, score 1.8e-23
553482010157	PS00632 Ribosomal protein S4 signature.
553482010158	HMMPfam hit to PF00163, Ribosomal protein S4/S9 N-terminal domai, score 5.9e-26
553482010159	Uncharacterized protein conserved in bacteria [Function unknown]; Region: Veg; COG4466
553482010160	HMMPfam hit to PF06257, Protein of unknown function (DUF1021), score 4.8e-40
553482010161	replicative DNA helicase; Provisional; Region: PRK05748
553482010162	DnaB-like helicase N terminal domain; Region: DnaB; pfam00772
553482010163	DnaB helicase C terminal domain. The hexameric helicase DnaB unwinds the DNA duplex at the  chromosome replication fork. Although the mechanism by which DnaB both couples ATP hydrolysis to translocation along DNA and denatures the duplex is unknown, a...; Region: DnaB_C; cd00984
553482010164	Walker A motif; other site
553482010165	ATP binding site [chemical binding]; other site
553482010166	Walker B motif; other site
553482010167	DNA binding loops [nucleotide binding]
553482010168	HMMPfam hit to PF03796, DnaB-like helicase C terminal domain, score 1.9e-136
553482010169	PS00017 ATP/GTP-binding site motif A (P-loop).
553482010170	HMMPfam hit to PF00772, DnaB-like helicase N terminal domain, score 5e-47
553482010171	50S ribosomal protein L9; Reviewed; Region: rplI; PRK00137
553482010172	Ribosomal protein L9, N-terminal domain; Region: Ribosomal_L9_N; pfam01281
553482010173	Ribosomal protein L9, C-terminal domain; Region: Ribosomal_L9_C; pfam03948
553482010174	HMMPfam hit to PF03948, Ribosomal protein L9, C-terminal domai, score 1.3e-16
553482010175	HMMPfam hit to PF01281, Ribosomal protein L9, N-terminal domai, score 9.6e-18
553482010176	PS00651 Ribosomal protein L9 signature.
553482010177	Predicted signaling protein consisting of a modified GGDEF domain and a DHH domain [Signal transduction mechanisms]; Region: COG3887
553482010178	DHH family; Region: DHH; pfam01368
553482010179	DHHA1 domain; Region: DHHA1; pfam02272
553482010180	HMMPfam hit to PF02272, DHHA1 domain, score 1.2e-12
553482010181	HMMPfam hit to PF01368, DHH family, score 6.7e-41
553482010182	2 transmembrane helices predicted for SEQ2205 by TMHMM2.0 at aa 4-26 and 33-52
553482010183	tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA; Validated; Region: PRK05192
553482010184	NAD(FAD)-utilizing enzyme possibly involved in translation [Translation, ribosomal structure and biogenesis]; Region: Gid; COG1206
553482010185	GidA associated domain 3; Region: GIDA_assoc_3; pfam13932
553482010186	HMMPfam hit to PF01134, Glucose inhibited division protein A, score 2.7e-263
553482010187	PS01281 Glucose inhibited division protein A family signature 2.
553482010188	PS01280 Glucose inhibited division protein A family signature 1.
553482010189	Nudix hydrolase is a superfamily of enzymes found in all three kingdoms of life, and it catalyzes the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+...; Region: Nudix_Hydrolase; cl00447
553482010190	nudix motif; other site
553482010191	HMMPfam hit to PF00293, NUDIX domain, score 1.3e-10
553482010192	PS00893 mutT domain signature.
553482010193	Predicted tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain [Translation, ribosomal structure and biogenesis]; Region: TrmU; COG0482
553482010194	tRNA methyl transferase. This family represents tRNA(5-methylaminomethyl-2-thiouridine)-methyltransferase which is involved in the biosynthesis of the modified nucleoside 5-methylaminomethyl-2-thiouridine present in the wobble position of some tRNAs; Region: tRNA_Me_trans; cd01998
553482010195	HMMPfam hit to PF01171, PP-loop family, score 0.074
553482010196	L-serine dehydratase, iron-sulfur-dependent, beta subunit; Region: sda_beta; TIGR00719
553482010197	Serine dehydratase beta chain; Region: SDH_beta; pfam03315
553482010198	C-terminal ACT domain of the L-serine dehydratase (LSD), iron-sulfur-dependent, beta subunit; Region: ACT_LSD; cd04903
553482010199	putative L-serine binding site [chemical binding]; other site
553482010200	HMMPfam hit to PF03315, Serine dehydratase beta chain, score 1.6e-50
553482010201	HMMPfam hit to PF01842, ACT domain, score 3e-07
553482010202	Serine dehydratase alpha chain; Region: SDH_alpha; cl12120
553482010203	L-serine deaminase [Amino acid transport and metabolism]; Region: SdaA; COG1760
553482010204	HMMPfam hit to PF03313, Serine dehydratase alpha chain, score 2.9e-107
553482010205	PS00867 Carbamoyl-phosphate synthase subdomain signature 2.
553482010206	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482010207	Predicted phosphatases [General function prediction only]; Region: Gph; COG0546
553482010208	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
553482010209	motif II; other site
553482010210	HMMPfam hit to PF00702, haloacid dehalogenase-like hydrolase, score 1.9e-15
553482010211	PS00225 Crystallins beta and gamma 'Greek key' motif signature.
553482010212	HMMPfam hit to PF06737, Transglycosylase-like domain, score 1.2e-19
553482010213	1 transmembrane helix predicted for SEQ2212 by TMHMM2.0 at aa 12-31
553482010214	ABC-type cobalt transport system, permease component CbiQ and related transporters [Inorganic ion transport and metabolism]; Region: CbiQ; COG0619
553482010215	4 transmembrane helices predicted for SEQ2213 by TMHMM2.0 at aa 25-57, 72-94, 106-128 and 245-262
553482010216	HMMPfam hit to PF02361, Cobalt transport protein, score 2.8e-64
553482010217	cobalt transporter ATP-binding subunit; Provisional; Region: cbiO; PRK13649
553482010218	First domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain1; cd03225
553482010219	Walker A/P-loop; other site
553482010220	ATP binding site [chemical binding]; other site
553482010221	Q-loop/lid; other site
553482010222	ABC transporter signature motif; other site
553482010223	Walker B; other site
553482010224	D-loop; other site
553482010225	H-loop/switch region; other site
553482010226	HMMPfam hit to PF00005, ABC transporter, score 7.3e-55
553482010227	PS00211 ABC transporters family signature.
553482010228	PS00017 ATP/GTP-binding site motif A (P-loop).
553482010229	cobalt transporter ATP-binding subunit; Provisional; Region: cbiO; PRK13650
553482010230	First domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain1; cd03225
553482010231	Walker A/P-loop; other site
553482010232	ATP binding site [chemical binding]; other site
553482010233	Q-loop/lid; other site
553482010234	ABC transporter signature motif; other site
553482010235	Walker B; other site
553482010236	D-loop; other site
553482010237	H-loop/switch region; other site
553482010238	HMMPfam hit to PF00005, ABC transporter, score 4.5e-58
553482010239	PS00211 ABC transporters family signature.
553482010240	PS00017 ATP/GTP-binding site motif A (P-loop).
553482010241	CDP-alcohol phosphatidyltransferase; Region: CDP-OH_P_transf; cl00453
553482010242	HMMPfam hit to PF01066, CDP-alcohol phosphatidyltransferase, score 1.4e-36
553482010243	3 transmembrane helices predicted for SEQ2216 by TMHMM2.0 at aa 21-43, 78-100 and 140-162
553482010244	PS00379 CDP-alcohol phosphatidyltransferases signature.
553482010245	Predicted transcriptional regulator contains Xre-like HTH domain [Function unknown]; Region: COG1426
553482010246	Helix-turn-helix domain; Region: HTH_25; pfam13413
553482010247	1 transmembrane helix predicted for SEQ2217 by TMHMM2.0 at aa 172-194
553482010248	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
553482010249	Insulinase (Peptidase family M16); Region: Peptidase_M16; pfam00675
553482010250	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
553482010251	Uncharacterized protein family (UPF0160); Region: UPF0160; cl01749
553482010252	HMMPfam hit to PF05193, Peptidase M16 inactive domain, score 1.2e-15
553482010253	HMMPfam hit to PF00675, Insulinase (Peptidase family M16), score 1.8e-08
553482010254	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
553482010255	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
553482010256	HMMPfam hit to PF05193, Peptidase M16 inactive domain, score 5.3e-28
553482010257	S4 domain; Region: S4_2; pfam13275
553482010258	HMMPfam hit to PF01479, S4 domain, score 0.0089
553482010259	recombination protein F; Reviewed; Region: recF; PRK00064
553482010260	ATP-binding cassette domain of RecF; Region: ABC_RecF; cd03242
553482010261	Walker A/P-loop; other site
553482010262	ATP binding site [chemical binding]; other site
553482010263	Q-loop/lid; other site
553482010264	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
553482010265	ABC transporter signature motif; other site
553482010266	Walker B; other site
553482010267	D-loop; other site
553482010268	H-loop/switch region; other site
553482010269	HMMPfam hit to PF02463, RecF/RecN/SMC N terminal domain, score 2.5e-09
553482010270	PS00017 ATP/GTP-binding site motif A (P-loop).
553482010271	PS00617 RecF protein signature 1.
553482010272	PS00618 RecF protein signature 2.
553482010273	Putative glucose uptake permease [Carbohydrate transport and metabolism]; Region: GlcU; COG4975
553482010274	9 transmembrane helices predicted for SEQ2222 by TMHMM2.0 at aa 5-22, 32-51, 58-80, 114-133, 153-175, 179-200, 207-229, 234-256 and 268-285
553482010275	HMMPfam hit to PF06800, Sugar transport protein, score 8e-154
553482010276	Protein of unknown function (DUF2974); Region: DUF2974; pfam11187
553482010277	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
553482010278	Helix-turn-helix domain; Region: HTH_28; pfam13518
553482010279	Predicted helix-turn-helix motif with score 1140.000, SD 3.07 at aa 19-40, sequence KSIKCLSEKFSIAESDLKYMIR
553482010280	HMMPfam hit to PF01527, Transposase, score 0.00062
553482010281	HMMPfam hit to PF02178, no description, score 0.21
553482010283	1 transmembrane helix predicted for SEQ2227 by TMHMM2.0 at aa 4-21
553482010284	Protein of unknown function (DUF1310); Region: DUF1310; pfam07006
553482010285	HMMPfam hit to PF07006, Protein of unknown function (DUF1310), score 5.7e-21
553482010286	1 transmembrane helix predicted for SEQ2228 by TMHMM2.0 at aa 21-43
553482010287	Protein of unknown function (DUF1310); Region: DUF1310; pfam07006
553482010288	HMMPfam hit to PF07006, Protein of unknown function (DUF1310), score 6.1e-23
553482010289	1 transmembrane helix predicted for SEQ2229 by TMHMM2.0 at aa 4-23
553482010290	inosine 5'-monophosphate dehydrogenase; Reviewed; Region: PRK05567
553482010291	TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl17186
553482010292	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in the inosine 5' monophosphate dehydrogenase (IMPDH) protein.  IMPDH is an essential enzyme that catalyzes the first step unique to GTP synthesis, playing a...; Region: CBS_pair_IMPDH; cd04601
553482010293	IMPDH: The catalytic domain of the inosine monophosphate dehydrogenase. IMPDH catalyzes the NAD-dependent oxidation of inosine 5'-monophosphate (IMP) to xanthosine 5' monophosphate (XMP). It is a rate-limiting step in the de novo synthesis of...; Region: IMPDH; cd00381
553482010294	active site
553482010295	HMMPfam hit to PF00478, IMP dehydrogenase / GMP reductase domain, score 2.9e-241
553482010296	HMMPfam hit to PF03060, 2-nitropropane dioxygenase, score 0.0052
553482010297	HMMPfam hit to PF01791, DeoC/LacD family aldolase, score 0.0046
553482010298	PS00487 IMP dehydrogenase / GMP reductase signature.
553482010299	HMMPfam hit to PF00571, CBS domain pair, score 1.8e-28
553482010300	tryptophanyl-tRNA synthetase II; Reviewed; Region: PRK12282
553482010301	catalytic core domain of tryptophanyl-tRNA synthetase; Region: TrpRS_core; cd00806
553482010302	active site
553482010303	HIGH motif; other site
553482010304	dimer interface [polypeptide binding]; other site
553482010305	KMSKS motif; other site
553482010306	HMMPfam hit to PF00579, tRNA synthetases class I (W and Y), score 7.2e-84
553482010307	PS00178 Aminoacyl-transfer RNA synthetases class-I signature.
553482010308	Uncharacterized conserved protein [Function unknown]; Region: COG1284
553482010309	Uncharacterized BCR, YitT family COG1284; Region: DUF161; pfam02588
553482010310	Uncharacterized BCR, YitT family COG1284; Region: DUF161; pfam02588
553482010311	Uncharacterized protein conserved in bacteria (DUF2179); Region: DUF2179; pfam10035
553482010312	5 transmembrane helices predicted for SEQ2232 by TMHMM2.0 at aa 5-27, 47-69, 103-122, 142-164 and 171-190
553482010313	HMMPfam hit to PF02588, Uncharacterized BCR, YitT family COG1284, score 9.9e-23
553482010314	HMMPfam hit to PF02588, Uncharacterized BCR, YitT family COG1284, score 5.8e-21
553482010315	ABC transporter ATP-binding protein; Provisional; Region: PRK15064
553482010316	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
553482010317	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
553482010318	ABC transporter; Region: ABC_tran_2; pfam12848
553482010319	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
553482010320	HMMPfam hit to PF00005, ABC transporter, score 3.3e-44
553482010321	PS00017 ATP/GTP-binding site motif A (P-loop).
553482010322	HMMPfam hit to PF00005, ABC transporter, score 8.4e-19
553482010323	PS00211 ABC transporters family signature.
553482010324	Predicted membrane protein [Function unknown]; Region: COG4485
553482010325	14 transmembrane helices predicted for SEQ2234 by TMHMM2.0 at aa 13-35, 77-99, 106-125, 135-152, 159-178, 193-215, 228-250, 290-312, 319-336, 351-373, 378-400, 405-427, 434-456 and 831-853
553482010326	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482010327	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
553482010328	rRNA large subunit methyltransferase; Provisional; Region: PRK00103
553482010329	HMMPfam hit to PF02590, Uncharacterized ACR, COG1576, score 2.2e-92
553482010330	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
553482010331	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
553482010332	protein binding site [polypeptide binding]; other site
553482010333	1 transmembrane helix predicted for SEQ2237 by TMHMM2.0 at aa 10-32
553482010334	HMMPfam hit to PF00089, Trypsin, score 7e-16
553482010335	Stage 0 sporulation protein J (antagonist of Soj) containing ParB-like nuclease domain [Transcription]; Region: Spo0J; COG1475
553482010336	ParB-like nuclease domain; Region: ParBc; pfam02195
553482010337	KorB domain; Region: KorB; pfam08535
553482010338	HMMPfam hit to PF02195, ParB-like nuclease domain, score 7.1e-36
553482010339	Predicted helix-turn-helix motif with score 1642.000, SD 4.78 at aa 119-140, sequence MTHEDIATYMGKSRPYISNTIR