-- dump date 20140620_081937 -- class Genbank::CDS -- table cds -- table main -- field 1 id -- field 2 GI -- field 3 GeneID -- field 4 chrom_position -- field 5 chromosome -- field 6 codon_start -- field 7 contig -- field 8 description -- field 9 end_pos -- field 10 gene -- field 11 gene_id -- field 12 name -- field 13 organism -- field 14 product -- field 15 protein_id -- field 16 start_pos -- field 17 strand -- field 18 taxid -- field 19 type -- header -- id GI GeneID chrom_position chromosome codon_start contig description end_pos gene gene_id name organism product protein_id start_pos strand taxid type YP_002122401.1 195977157 6760380 233..1585 1 NC_011134.1 binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication; can also affect transcription of multiple genes including itself.; chromosome replication initiator DnaA 1585 dnaA 6760380 dnaA Streptococcus equi subsp. zooepidemicus MGCS10565 chromosome replication initiator DnaA YP_002122401.1 233 D 552526 CDS YP_002122402.1 195977158 6760876 1742..2878 1 NC_011134.1 binds the polymerase to DNA and acts as a sliding clamp; DNA polymerase III subunit beta 2878 dnaN 6760876 dnaN Streptococcus equi subsp. zooepidemicus MGCS10565 DNA polymerase III subunit beta YP_002122402.1 1742 D 552526 CDS YP_002122403.1 195977159 6760878 2956..3153 1 NC_011134.1 similar to ref|ZP_00784446.1| conserved hypothetical protein [Streptococcus agalactiae COH1]; hypothetical protein 3153 6760878 Sez_0003 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002122403.1 2956 D 552526 CDS YP_002122404.1 195977160 6760883 3274..3639 1 NC_011134.1 similar to ref|YP_001199566.1| Predicted transcriptional regulator [Streptococcus suis 98HAH33]; Unknown, COG1396 Predicted transcriptional regulators.; hypothetical protein 3639 6760883 Sez_0004 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002122404.1 3274 D 552526 CDS YP_002122405.1 195977161 6761764 3723..4838 1 NC_011134.1 translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1; GTP-dependent nucleic acid-binding protein EngD 4838 6761764 Sez_0005 Streptococcus equi subsp. zooepidemicus MGCS10565 GTP-dependent nucleic acid-binding protein EngD YP_002122405.1 3723 D 552526 CDS YP_002122406.1 195977162 6761698 4995..5564 1 NC_011134.1 Enables the recycling of peptidyl-tRNAs produced at termination of translation; peptidyl-tRNA hydrolase 5564 pth 6761698 pth Streptococcus equi subsp. zooepidemicus MGCS10565 peptidyl-tRNA hydrolase YP_002122406.1 4995 D 552526 CDS YP_002122407.1 195977163 6761703 5567..9061 1 NC_011134.1 similar to ref|NP_801268.1| transcription-repair coupling factor [Streptococcus pyogenes SSI-1]; Necessary for strand-specific repair. A lesion in the template strand blocks the RNA polymerase complex (RNAP). The RNAP-DNA-RNA complex is specifically recognized by TRCF which releases RNAP and the truncated transcript; the TCRF may replace RNAP at the lesion site and then recruit the uvrA/B/C repair system.; transcription-repair coupling factor 9061 6761703 Sez_0007 Streptococcus equi subsp. zooepidemicus MGCS10565 transcription-repair coupling factor YP_002122407.1 5567 D 552526 CDS YP_002122408.1 195977164 6760885 9030..10541 1 NC_011134.1 similar to ref|NP_814052.1| polysaccharide biosynthesis family protein [Enterococcus faecalis V583]; Unknown, COG2244 Membrane protein involved in the export of O-antigen and teichoic acid.; polysaccharide biosynthesis family protein 10541 6760885 Sez_0008 Streptococcus equi subsp. zooepidemicus MGCS10565 polysaccharide biosynthesis family protein YP_002122408.1 9030 D 552526 CDS YP_002122409.1 195977165 6760884 10572..10844 1 NC_011134.1 similar to ref|ZP_00780251.1| S4 RNA-binding domain protein [Streptococcus agalactiae 18RS21]; Unknown, COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog).; heat shock protein 15 10844 6760884 Sez_0009 Streptococcus equi subsp. zooepidemicus MGCS10565 heat shock protein 15 YP_002122409.1 10572 D 552526 CDS YP_002122410.1 195977166 6761743 10855..11202 1 NC_011134.1 similar to ref|YP_599604.1| Cell division protein DIVIC [Streptococcus pyogenes MGAS2096]; cell division protein DivIC 11202 6761743 Sez_0010 Streptococcus equi subsp. zooepidemicus MGCS10565 cell division protein DivIC YP_002122410.1 10855 D 552526 CDS YP_002122411.1 195977167 6761733 11344..12630 1 NC_011134.1 similar to ref|ZP_00366568.1| COG2367: Beta-lactamase class A [Streptococcus pyogenes M49 591]; beta-lactamase 12630 6761733 Sez_0011 Streptococcus equi subsp. zooepidemicus MGCS10565 beta-lactamase YP_002122411.1 11344 D 552526 CDS YP_002122412.1 195977168 6760881 12627..13910 1 NC_011134.1 similar to ref|YP_059329.1| tRNA(Ile)-lysidine synthetase [Streptococcus pyogenes MGAS10394]; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.; tRNA(Ile)-lysidine synthase 13910 6760881 Sez_0012 Streptococcus equi subsp. zooepidemicus MGCS10565 tRNA(Ile)-lysidine synthase YP_002122412.1 12627 D 552526 CDS YP_002122413.1 195977169 6761742 13915..14457 1 NC_011134.1 similar to ref|NP_606347.1| hypoxanthine-guanine phosphoribosyltransferase [Streptococcus pyogenes MGAS8232]; This Enzyme Acts Exclusively On Hypoxanthine; It Does Not Act On Guanine (By Similarity).; hypoxanthine-guanine phosphoribosyltransferase Hpt 14457 hpt 6761742 hpt Streptococcus equi subsp. zooepidemicus MGCS10565 hypoxanthine-guanine phosphoribosyltransferase Hpt YP_002122413.1 13915 D 552526 CDS YP_002122414.1 195977170 6761729 14533..16452 1 NC_011134.1 similar to ref|YP_279483.1| cell division protein [Streptococcus pyogenes MGAS6180]; Seems to act as an ATP-dependent zinc metallopeptidase.; cell division protein FtsH-like 16452 ftsH 6761729 ftsH Streptococcus equi subsp. zooepidemicus MGCS10565 cell division protein FtsH-like YP_002122414.1 14533 D 552526 CDS YP_002122415.1 195977171 6760882 16542..18005 1 NC_011134.1 similar to ref|YP_059333.1| Amino acid permease [Streptococcus pyogenes MGAS10394]; Involved in the transport of the cationic amino acids (arginine, lysine and ornithine).; cationic amino acid transporter - APC superfamily 18005 6760882 Sez_0015 Streptococcus equi subsp. zooepidemicus MGCS10565 cationic amino acid transporter - APC superfamily YP_002122415.1 16542 D 552526 CDS YP_002122416.1 195977172 6761046 24838..25701 1 NC_011134.1 similar to ref|NP_346626.1| rod shape-determining protein MreC [Streptococcus pneumoniae TIGR4]; Involved In Formation Of The Rod Shape Of The Cell. May Also Contribute To Regulation Of Formation Of Penicillin-Binding Proteins.; rod shape-determining protein MreC 25701 mreC 6761046 mreC Streptococcus equi subsp. zooepidemicus MGCS10565 rod shape-determining protein MreC YP_002122416.1 24838 D 552526 CDS YP_002122417.1 195977173 6761786 25704..26207 1 NC_011134.1 similar to ref|NP_720504.1| cell shape-determining protein MreD [Streptococcus mutans UA159]; MreD (murein formation D) protein is involved in the rod shape determination in Escherichia coli, and more generally in cell shape determination of bacteria whether or not they are rod-shaped.; cell shape-determining protein MreD 26207 mreD 6761786 mreD Streptococcus equi subsp. zooepidemicus MGCS10565 cell shape-determining protein MreD YP_002122417.1 25704 D 552526 CDS YP_002122418.1 195977174 6761695 26303..27481 1 NC_011134.1 similar to ref|YP_597626.1| Secreted protein [Streptococcus pyogenes MGAS10270]; pfam05257, CHAP domain. This domain corresponds to an amidase function. Many of these proteins are involved in cell wall metabolism of bacteria. This domain is found at the N-terminus of the bifunctional Escherichia coli GSP synthetase/GSP amidase, where is functions as a glutathionylspermidine amidase.; secreted antigen GbpB/SagA/PcsB, peptidoglycan hydrolase 27481 6761695 Sez_0018 Streptococcus equi subsp. zooepidemicus MGCS10565 secreted antigen GbpB/SagA/PcsB, peptidoglycan hydrolase YP_002122418.1 26303 D 552526 CDS YP_002122419.1 195977175 6760874 27574..28548 1 NC_011134.1 catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP; ribose-phosphate pyrophosphokinase 28548 prs 6760874 prs Streptococcus equi subsp. zooepidemicus MGCS10565 ribose-phosphate pyrophosphokinase YP_002122419.1 27574 D 552526 CDS YP_002122420.1 195977176 6760858 28908..29678 1 NC_011134.1 involved in DNA repair and RecFOR pathway recombination; RecFOR proteins displace ssDNA-binding protein and facilitate the production of RecA-coated ssDNA; DNA repair protein RecO 29678 recO 6760858 recO Streptococcus equi subsp. zooepidemicus MGCS10565 DNA repair protein RecO YP_002122420.1 28908 D 552526 CDS YP_002122421.1 195977177 6760686 29794..30801 1 NC_011134.1 involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsY; glycerol-3-phosphate acyltransferase PlsX 30801 plsX 6760686 plsX Streptococcus equi subsp. zooepidemicus MGCS10565 glycerol-3-phosphate acyltransferase PlsX YP_002122421.1 29794 D 552526 CDS YP_002122422.1 195977178 6760785 30794..31042 1 NC_011134.1 carries the fatty acid chain in fatty acid biosynthesis; acyl carrier protein 31042 acpP 6760785 acpP Streptococcus equi subsp. zooepidemicus MGCS10565 acyl carrier protein YP_002122422.1 30794 D 552526 CDS YP_002122423.1 195977179 6760696 31193..31903 1 NC_011134.1 catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis; SAICAR synthase; phosphoribosylaminoimidazolesuccinocarboxamide synthase 31903 purC 6760696 purC Streptococcus equi subsp. zooepidemicus MGCS10565 phosphoribosylaminoimidazolesuccinocarboxamide synthase YP_002122423.1 31193 D 552526 CDS YP_002122424.1 195977180 6760680 32082..35822 1 NC_011134.1 similar to ref|YP_819618.1| Phosphoribosylformylglycinamidine (FGAM) synthase [Streptococcus thermophilus LMD-9]; Unknown, proposed to phosphorylate an amide oxygen of the purine nucleotide using ATP, activating the carbon of the resulting iminophosphate for nucleophilic attack.; phosphoribosylformylglycinamidine synthase PurL 35822 purL 6760680 purL Streptococcus equi subsp. zooepidemicus MGCS10565 phosphoribosylformylglycinamidine synthase PurL YP_002122424.1 32082 D 552526 CDS YP_002122425.1 195977181 6760614 35941..37398 1 NC_011134.1 Catalyzes first step of the de novo purine nucleotide biosynthetic pathway; amidophosphoribosyltransferase 37398 purF 6760614 purF Streptococcus equi subsp. zooepidemicus MGCS10565 amidophosphoribosyltransferase YP_002122425.1 35941 D 552526 CDS YP_002122426.1 195977182 6760583 37455..38477 1 NC_011134.1 catalyzes the formation of 1-(5-phosphoribosyl)-5-aminoimidazole from 2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in purine biosynthesis; phosphoribosylaminoimidazole synthetase 38477 purM 6760583 purM Streptococcus equi subsp. zooepidemicus MGCS10565 phosphoribosylaminoimidazole synthetase YP_002122426.1 37455 D 552526 CDS YP_002122427.1 195977183 6761655 38474..39031 1 NC_011134.1 glycinamide ribonucleotide transformylase; GAR Tfase; catalyzes the synthesis of 5'-phosphoribosylformylglycinamide from 5'-phosphoribosylglycinamide and 10-formyltetrahydrofolate; PurN requires formyl folate for the reaction unlike PurT which uses formate; phosphoribosylglycinamide formyltransferase 39031 purN 6761655 purN Streptococcus equi subsp. zooepidemicus MGCS10565 phosphoribosylglycinamide formyltransferase YP_002122427.1 38474 D 552526 CDS YP_002122428.1 195977184 6761679 39223..40725 1 NC_011134.1 involved in de novo purine biosynthesis; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 40725 purH 6761679 purH Streptococcus equi subsp. zooepidemicus MGCS10565 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase YP_002122428.1 39223 D 552526 CDS YP_002122429.1 195977185 6761613 complement(41103..42257) 1 NC_011134.1 similar to ref|YP_281392.1| autolysin [Streptococcus pyogenes MGAS5005]; Unknown, surface antigen; autolysin; choline binding protein.; autolysin 42257 6761613 Sez_0029 Streptococcus equi subsp. zooepidemicus MGCS10565 autolysin YP_002122429.1 41103 R 552526 CDS YP_002122430.1 195977186 6760875 42571..43875 1 NC_011134.1 catalyzes the formation of N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-D-ribosylamine and glycine in purine biosynthesis; phosphoribosylamine--glycine ligase 43875 purD 6760875 purD Streptococcus equi subsp. zooepidemicus MGCS10565 phosphoribosylamine--glycine ligase YP_002122430.1 42571 D 552526 CDS YP_002122431.1 195977187 6761674 44103..44591 1 NC_011134.1 similar to ref|YP_001127629.1| phosphoribosylaminoimidazole carboxylase catalytic subunit [Streptococcus pyogenes str. Manfredo]; This subunit can alone transform AIR to CAIR, but in association with purK, which possesses an ATPase activity, an enzyme complex is produced which is capable of converting AIR to CAIR efficiently under physiological condition.; phosphoribosylaminoimidazole carboxylase catalytic subunit PurE 44591 purE 6761674 purE Streptococcus equi subsp. zooepidemicus MGCS10565 phosphoribosylaminoimidazole carboxylase catalytic subunit PurE YP_002122431.1 44103 D 552526 CDS YP_002122432.1 195977188 6760877 44578..45669 1 NC_011134.1 With PurE catalyzes the conversion of aminoimidazole ribonucleotide to carboxyaminoimidazole ribonucleotide in the de novo purine nucleotide biosynthetic pathway; phosphoribosylaminoimidazole carboxylase ATPase subunit 45669 purK 6760877 purK Streptococcus equi subsp. zooepidemicus MGCS10565 phosphoribosylaminoimidazole carboxylase ATPase subunit YP_002122432.1 44578 D 552526 CDS YP_002122433.1 195977189 6760873 45679..45903 1 NC_011134.1 similar to ref|NP_734515.1| hypothetical protein gbs0045 [Streptococcus agalactiae NEM316]; hypothetical protein 45903 6760873 Sez_0033 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002122433.1 45679 D 552526 CDS YP_002122434.1 195977190 6761463 47940..48854 1 NC_011134.1 similar to ref|YP_059401.1| Transcriptional regulator [Streptococcus pyogenes MGAS10394]; transcriptional regulator 48854 6761463 Sez_0036 Streptococcus equi subsp. zooepidemicus MGCS10565 transcriptional regulator YP_002122434.1 47940 D 552526 CDS YP_002122435.1 195977191 6761475 49069..50070 1 NC_011134.1 promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration; Holliday junction DNA helicase RuvB 50070 ruvB 6761475 ruvB Streptococcus equi subsp. zooepidemicus MGCS10565 Holliday junction DNA helicase RuvB YP_002122435.1 49069 D 552526 CDS YP_002122436.1 195977192 6760879 complement(50082..50270) 1 NC_011134.1 hypothetical protein 50270 6760879 Sez_0038 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002122436.1 50082 R 552526 CDS YP_002122437.1 195977193 6761704 50356..50814 1 NC_011134.1 similar to ref|NP_268454.1| protein-tyrosine phosphatase [Streptococcus pyogenes M1 GAS]; Acts on tyrosine phosphorylated proteins, low-MW aryl phosphates and natural and synthetic acyl phosphates. Isoform 3 does not possess phosphatase activity.; phosphotyrosine protein phosphatase 50814 acp1 6761704 acp1 Streptococcus equi subsp. zooepidemicus MGCS10565 phosphotyrosine protein phosphatase YP_002122437.1 50356 D 552526 CDS YP_002122438.1 195977194 6761751 50820..51221 1 NC_011134.1 similar to ref|NP_606371.1| hypothetical protein spyM18_0041 [Streptococcus pyogenes MGAS8232]; Unknown, MORN repeat motif family protein.; hypothetical protein 51221 6761751 Sez_0040 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002122438.1 50820 D 552526 CDS YP_002122439.1 195977195 6761652 53419..56061 1 NC_011134.1 similar to ref|YP_281403.1| alcohol dehydrogenase/acetaldehyde dehydrogenase (acetylating) [Streptococcus pyogenes MGAS5005]; This enzyme has two NAD(+)-dependent activities:ADH and ACDH. May be a critical enzyme in the fermentative pathway.; bifunctional acetaldehyde-CoA/alcohol dehydrogenase 56061 adh2 6761652 adh2 Streptococcus equi subsp. zooepidemicus MGCS10565 bifunctional acetaldehyde-CoA/alcohol dehydrogenase YP_002122439.1 53419 D 552526 CDS YP_002122440.1 195977196 6761671 56329..56535 1 NC_011134.1 hypothetical protein 56535 6761671 Sez_0044 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002122440.1 56329 D 552526 CDS YP_002122441.1 195977197 6760792 56556..57608 1 NC_011134.1 similar to ref|YP_598559.1| Zn-dependent alcohol dehydrogenase [Streptococcus pyogenes MGAS10270]; Zn-dependent alcohol dehydrogenases and related dehydrogenases 57608 adh 6760792 adh Streptococcus equi subsp. zooepidemicus MGCS10565 Zn-dependent alcohol dehydrogenases and related dehydrogenases YP_002122441.1 56556 D 552526 CDS YP_002122442.1 195977198 6760880 57813..58829 1 NC_011134.1 similar to zinc-dependent eukaryotic ADH enzymes and distinct from fermentative ADHs; alcohol dehydrogenase 58829 adhA 6760880 adhA Streptococcus equi subsp. zooepidemicus MGCS10565 alcohol dehydrogenase YP_002122442.1 57813 D 552526 CDS YP_002122443.1 195977199 6761720 59549..61141 1 NC_011134.1 similar to ref|YP_001034708.1| ABC-type multidrug/protein/lipid transport system (pediocin PA-1 exporter), ATPase and permease components, [Streptococcus sanguinis SK36]; multidrug ABC transporter ATPase 61141 6761720 Sez_0047 Streptococcus equi subsp. zooepidemicus MGCS10565 multidrug ABC transporter ATPase YP_002122443.1 59549 D 552526 CDS YP_002122444.1 195977200 6761595 61312..62433 1 NC_011134.1 similar to ref|NP_815050.1| HesA/MoeB/ThiF family protein [Enterococcus faecalis V583]; HesA/MoeB/ThiF family protein 62433 6761595 Sez_0048 Streptococcus equi subsp. zooepidemicus MGCS10565 HesA/MoeB/ThiF family protein YP_002122444.1 61312 D 552526 CDS YP_002122445.1 195977201 6761636 62426..63601 1 NC_011134.1 similar to ref|YP_196698.1| Hypothetical zinc protease [Ehrlichia ruminantium str. Gardel]; zinc protease 63601 6761636 Sez_0049 Streptococcus equi subsp. zooepidemicus MGCS10565 zinc protease YP_002122445.1 62426 D 552526 CDS YP_002122446.1 195977202 6760886 complement(63585..64448) 1 NC_011134.1 similar to ref|YP_140611.1| positive transcriptional regulator MutR family [Streptococcus thermophilus CNRZ1066]; positive transcriptional regulator, MutR family 64448 6760886 Sez_0050 Streptococcus equi subsp. zooepidemicus MGCS10565 positive transcriptional regulator, MutR family YP_002122446.1 63585 R 552526 CDS YP_002122447.1 195977203 6760888 65062..65361 1 NC_011134.1 hypothetical protein 65361 6760888 Sez_0051 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002122447.1 65062 D 552526 CDS YP_002122448.1 195977204 6760889 65600..67075 1 NC_011134.1 catalyzes the formation of L-threonine from O-phospho-L-homoserine; threonine synthase 67075 thnsl 6760889 thnsl Streptococcus equi subsp. zooepidemicus MGCS10565 threonine synthase YP_002122448.1 65600 D 552526 CDS YP_002122449.1 195977205 6761791 67115..67774 1 NC_011134.1 similar to ref|YP_059409.1| Na+ driven multidrug efflux pump [Streptococcus pyogenes MGAS10394]; Multidrug efflux pump.; multi antimicrobial extrusion (MATE) family transporter 67774 6761791 Sez_0053 Streptococcus equi subsp. zooepidemicus MGCS10565 multi antimicrobial extrusion (MATE) family transporter YP_002122449.1 67115 D 552526 CDS YP_002122450.1 195977206 6761693 67671..68417 1 NC_011134.1 similar to ref|YP_059409.1| Na+ driven multidrug efflux pump [Streptococcus pyogenes MGAS10394]; Multidrug efflux pump.; multi antimicrobial extrusion (MATE) family transporter 68417 6761693 Sez_0054 Streptococcus equi subsp. zooepidemicus MGCS10565 multi antimicrobial extrusion (MATE) family transporter YP_002122450.1 67671 D 552526 CDS YP_002122451.1 195977207 6761772 68797..69105 1 NC_011134.1 NusE; involved in assembly of the 30S subunit; in the ribosome, this protein is involved in the binding of tRNA; in Escherichia coli this protein was also found to be involved in transcription antitermination; NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination; binding of NusB/S10 to boxA nucleates assembly of the antitermination complex; 30S ribosomal protein S10 69105 rpsJ 6761772 rpsJ Streptococcus equi subsp. zooepidemicus MGCS10565 30S ribosomal protein S10 YP_002122451.1 68797 D 552526 CDS YP_002122452.1 195977208 6761781 69403..70029 1 NC_011134.1 binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin; 50S ribosomal protein L3 70029 rplC 6761781 rplC Streptococcus equi subsp. zooepidemicus MGCS10565 50S ribosomal protein L3 YP_002122452.1 69403 D 552526 CDS YP_002122453.1 195977209 6760700 70054..70677 1 NC_011134.1 L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA; 50S ribosomal protein L4 70677 rplD 6760700 rplD Streptococcus equi subsp. zooepidemicus MGCS10565 50S ribosomal protein L4 YP_002122453.1 70054 D 552526 CDS YP_002122454.1 195977210 6760678 70725..70973 1 NC_011134.1 similar to ref|NP_268462.1| 50S ribosomal protein L23 [Streptococcus pyogenes M1 GAS]; Binds to a specific region on the 23S rRNA.; 50S ribosomal protein L23 70973 rplW 6760678 rplW Streptococcus equi subsp. zooepidemicus MGCS10565 50S ribosomal protein L23 YP_002122454.1 70725 D 552526 CDS YP_002122455.1 195977211 6760415 70991..71824 1 NC_011134.1 one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation; 50S ribosomal protein L2 71824 rplB 6760415 rplB Streptococcus equi subsp. zooepidemicus MGCS10565 50S ribosomal protein L2 YP_002122455.1 70991 D 552526 CDS YP_002122456.1 195977212 6760417 71876..72214 1 NC_011134.1 similar to gb|ABP89047.1| SSU ribosomal protein S19P [Streptococcus suis 05ZYH33]; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.; 30S ribosomal protein S19 72214 rpsS 6760417 rpsS Streptococcus equi subsp. zooepidemicus MGCS10565 30S ribosomal protein S19 YP_002122456.1 71876 D 552526 CDS YP_002122457.1 195977213 6760823 72230..72574 1 NC_011134.1 binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center; 50S ribosomal protein L22 72574 rplV 6760823 rplV Streptococcus equi subsp. zooepidemicus MGCS10565 50S ribosomal protein L22 YP_002122457.1 72230 D 552526 CDS YP_002122458.1 195977214 6760690 72587..73240 1 NC_011134.1 forms a complex with S10 and S14; binds the lower part of the 30S subunit head and the mRNA in the complete ribosome to position it for translation; 30S ribosomal protein S3 73240 rpsC 6760690 rpsC Streptococcus equi subsp. zooepidemicus MGCS10565 30S ribosomal protein S3 YP_002122458.1 72587 D 552526 CDS YP_002122459.1 195977215 6760414 73244..73657 1 NC_011134.1 located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e; 50S ribosomal protein L16 73657 rplP 6760414 rplP Streptococcus equi subsp. zooepidemicus MGCS10565 50S ribosomal protein L16 YP_002122459.1 73244 D 552526 CDS YP_002122460.1 195977216 6760364 73667..73873 1 NC_011134.1 one of the stabilizing components for the large ribosomal subunit; 50S ribosomal protein L29 73873 rpmC 6760364 rpmC Streptococcus equi subsp. zooepidemicus MGCS10565 50S ribosomal protein L29 YP_002122460.1 73667 D 552526 CDS YP_002122461.1 195977217 6760410 73901..74161 1 NC_011134.1 primary binding protein; helps mediate assembly; involved in translation fidelity; 30S ribosomal protein S17 74161 rpsQ 6760410 rpsQ Streptococcus equi subsp. zooepidemicus MGCS10565 30S ribosomal protein S17 YP_002122461.1 73901 D 552526 CDS YP_002122462.1 195977218 6761683 74186..74554 1 NC_011134.1 binds to the 23S rRNA between the centers for peptidyl transferase and GTPase; 50S ribosomal protein L14 74554 rplN 6761683 rplN Streptococcus equi subsp. zooepidemicus MGCS10565 50S ribosomal protein L14 YP_002122462.1 74186 D 552526 CDS YP_002122463.1 195977219 6761777 74638..74943 1 NC_011134.1 assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel; 50S ribosomal protein L24 74943 rplX 6761777 rplX Streptococcus equi subsp. zooepidemicus MGCS10565 50S ribosomal protein L24 YP_002122463.1 74638 D 552526 CDS YP_002122464.1 195977220 6761797 74967..75509 1 NC_011134.1 part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13; 50S ribosomal protein L5 75509 rplE 6761797 rplE Streptococcus equi subsp. zooepidemicus MGCS10565 50S ribosomal protein L5 YP_002122464.1 74967 D 552526 CDS YP_002122465.1 195977221 6760892 75525..75710 1 NC_011134.1 located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group appear to contain the zinc-binding motif; 30S ribosomal protein S14 75710 rpsN 6760892 rpsN Streptococcus equi subsp. zooepidemicus MGCS10565 30S ribosomal protein S14 YP_002122465.1 75525 D 552526 CDS YP_002122466.1 195977222 6761774 76043..76441 1 NC_011134.1 binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; 30S ribosomal protein S8 76441 rpsH 6761774 rpsH Streptococcus equi subsp. zooepidemicus MGCS10565 30S ribosomal protein S8 YP_002122466.1 76043 D 552526 CDS YP_002122467.1 195977223 6761701 76763..77299 1 NC_011134.1 ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance; 50S ribosomal protein L6 77299 rplF 6761701 rplF Streptococcus equi subsp. zooepidemicus MGCS10565 50S ribosomal protein L6 YP_002122467.1 76763 D 552526 CDS YP_002122468.1 195977224 6760893 77393..77758 1 NC_011134.1 binds 5S rRNA along with protein L5 and L25; 50S ribosomal protein L18 77758 rplR 6760893 rplR Streptococcus equi subsp. zooepidemicus MGCS10565 50S ribosomal protein L18 YP_002122468.1 77393 D 552526 CDS YP_002122469.1 195977225 6760898 77777..78271 1 NC_011134.1 located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance; 30S ribosomal protein S5 78271 rpsE 6760898 rpsE Streptococcus equi subsp. zooepidemicus MGCS10565 30S ribosomal protein S5 YP_002122469.1 77777 D 552526 CDS YP_002122470.1 195977226 6760897 78286..78468 1 NC_011134.1 L30 binds domain II of the 23S rRNA and the 5S rRNA; similar to eukaryotic protein L7; 50S ribosomal protein L30 78468 rpmD 6760897 rpmD Streptococcus equi subsp. zooepidemicus MGCS10565 50S ribosomal protein L30 YP_002122470.1 78286 D 552526 CDS YP_002122471.1 195977227 6760890 78670..79110 1 NC_011134.1 late assembly protein; 50S ribosomal protein L15 79110 rplO 6760890 rplO Streptococcus equi subsp. zooepidemicus MGCS10565 50S ribosomal protein L15 YP_002122471.1 78670 D 552526 CDS YP_002122472.1 195977228 6760896 79127..80431 1 NC_011134.1 forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase; preprotein translocase subunit SecY 80431 secY 6760896 secY Streptococcus equi subsp. zooepidemicus MGCS10565 preprotein translocase subunit SecY YP_002122472.1 79127 D 552526 CDS YP_002122473.1 195977229 6760891 80472..81224 1 NC_011134.1 similar to ref|ZP_01834380.1| adenylate kinase [Streptococcus pneumoniae SP23-BS72]; This small ubiquitous enzyme is essential for maintenance and cell growth.; adenylate kinase 81224 adk 6760891 adk Streptococcus equi subsp. zooepidemicus MGCS10565 adenylate kinase YP_002122473.1 80472 D 552526 CDS YP_002122474.1 195977230 6760887 81288..81560 1 NC_011134.1 stimulates the activities of the other two initiation factors, IF-2 and IF-3; translation initiation factor IF-1 81560 infA 6760887 infA Streptococcus equi subsp. zooepidemicus MGCS10565 translation initiation factor IF-1 YP_002122474.1 81288 D 552526 CDS YP_002122475.1 195977231 6760361 81586..81702 1 NC_011134.1 smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group have the motif; 50S ribosomal protein L36 81702 rpmJ 6760361 rpmJ Streptococcus equi subsp. zooepidemicus MGCS10565 50S ribosomal protein L36 YP_002122475.1 81586 D 552526 CDS YP_002122476.1 195977232 6760681 81720..82085 1 NC_011134.1 located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA; 30S ribosomal protein S13 82085 rpsM 6760681 rpsM Streptococcus equi subsp. zooepidemicus MGCS10565 30S ribosomal protein S13 YP_002122476.1 81720 D 552526 CDS YP_002122477.1 195977233 6760849 82103..82486 1 NC_011134.1 located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3; 30S ribosomal protein S11 82486 rpsK 6760849 rpsK Streptococcus equi subsp. zooepidemicus MGCS10565 30S ribosomal protein S11 YP_002122477.1 82103 D 552526 CDS YP_002122478.1 195977234 6760512 82533..83471 1 NC_011134.1 catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme; DNA-directed RNA polymerase subunit alpha 83471 rpoA 6760512 rpoA Streptococcus equi subsp. zooepidemicus MGCS10565 DNA-directed RNA polymerase subunit alpha YP_002122478.1 82533 D 552526 CDS YP_002122479.1 195977235 6761745 83486..83872 1 NC_011134.1 is a component of the macrolide binding site in the peptidyl transferase center; 50S ribosomal protein L17 83872 rplQ 6761745 rplQ Streptococcus equi subsp. zooepidemicus MGCS10565 50S ribosomal protein L17 YP_002122479.1 83486 D 552526 CDS YP_002122480.1 195977236 6760894 85192..85986 1 NC_011134.1 similar to ref|YP_850136.1| hypothetical protein lwe1939 [Listeria welshimeri serovar 6b str. SLCC5334]; hypothetical protein 85986 6760894 Sez_0084 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002122480.1 85192 D 552526 CDS YP_002122481.1 195977237 6761755 85983..86759 1 NC_011134.1 similar to ref|XP_597510.3| Gene info PREDICTED: similar to olfactory receptor MOR123-1 [Bos taurus]; hypothetical protein 86759 6761755 Sez_0085 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002122481.1 85983 D 552526 CDS YP_002122482.1 195977238 6761804 86749..87438 1 NC_011134.1 similar to gb|EDK97023.1| Gene info phosphoinositide-3-kinase, class 3, isoform CRA_c [Mus musculus]; hypothetical protein 87438 6761804 Sez_0086 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002122482.1 86749 D 552526 CDS YP_002122483.1 195977239 6761689 87471..87623 1 NC_011134.1 hypothetical protein 87623 6761689 Sez_0087 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002122483.1 87471 D 552526 CDS YP_002122484.1 195977240 6760437 87644..87937 1 NC_011134.1 similar to ref|YP_001449395.1| hypothetical protein SGO_0073 [Streptococcus gordonii str. Challis substr. CH1]; hypothetical protein 87937 6760437 Sez_0088 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002122484.1 87644 D 552526 CDS YP_002122485.1 195977241 6760848 complement(94623..95756) 1 NC_011134.1 similar to ref|YP_001197470.1| hypothetical protein SSU05_0100 [Streptococcus suis 05ZYH33]; Site-specific DNA recombination.; integrase 95756 int 6760848 int Streptococcus equi subsp. zooepidemicus MGCS10565 integrase YP_002122485.1 94623 R 552526 CDS YP_002122486.1 195977242 6762181 complement(95746..95952) 1 NC_011134.1 similar to ref|YP_001197471.1| hypothetical protein SSU05_0101 [Streptococcus suis 05ZYH33]; hypothetical protein 95952 6762181 Sez_0090 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002122486.1 95746 R 552526 CDS YP_002122487.1 195977243 6760634 complement(96013..96843) 1 NC_011134.1 similar to ref|YP_001197472.1| hypothetical protein SSU05_0102 [Streptococcus suis 05ZYH33]; Unknown, COG2946 phage replication protein RstA.; Cro/CI family transcriptional regulator 96843 6760634 Sez_0091 Streptococcus equi subsp. zooepidemicus MGCS10565 Cro/CI family transcriptional regulator YP_002122487.1 96013 R 552526 CDS YP_002122488.1 195977244 6760902 complement(97034..97441) 1 NC_011134.1 similar to ref|YP_001197473.1| hypothetical protein SSU05_0103 [Streptococcus suis 05ZYH33]; hypothetical protein 97441 6760902 Sez_0092 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002122488.1 97034 R 552526 CDS YP_002122489.1 195977245 6760633 complement(97730..99139) 1 NC_011134.1 similar to ref|YP_893172.1| FtsK/SpoIIIE family protein [Bacillus thuringiensis str. Al Hakam]; Unknown, COG1674 DNA segregation ATPase FtsK/SpoIIIE and related proteins.; DNA translocase FtsK 99139 6760633 Sez_0093 Streptococcus equi subsp. zooepidemicus MGCS10565 DNA translocase FtsK YP_002122489.1 97730 R 552526 CDS YP_002122490.1 195977246 6762254 complement(99857..100225) 1 NC_011134.1 similar to ref|NP_073692.1| tail protein [Bacillus phage GA-1]; hypothetical protein 100225 6762254 Sez_0094 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002122490.1 99857 R 552526 CDS YP_002122491.1 195977247 6760632 complement(100620..101180) 1 NC_011134.1 similar to ref|ZP_01829310.1| IS1167, transposase [Streptococcus pneumoniae SP18-BS74]; transposase IS1167 101180 6760632 Sez_0095 Streptococcus equi subsp. zooepidemicus MGCS10565 transposase IS1167 YP_002122491.1 100620 R 552526 CDS YP_002122492.1 195977248 6760903 complement(101346..101813) 1 NC_011134.1 similar to ref|ZP_01829310.1| IS1167, transposase [Streptococcus pneumoniae SP18-BS74]; transposase IS1193D-like 101813 6760903 Sez_0096 Streptococcus equi subsp. zooepidemicus MGCS10565 transposase IS1193D-like YP_002122492.1 101346 R 552526 CDS YP_002122493.1 195977249 6760905 complement(102187..103392) 1 NC_011134.1 similar to ref|YP_078429.1| Major facilitator superfamily [Bacillus licheniformis ATCC 14580]; Unknown, COG0477 Permeases of the major facilitator superfamily.; macrolide efflux protein 103392 6760905 Sez_0098 Streptococcus equi subsp. zooepidemicus MGCS10565 macrolide efflux protein YP_002122493.1 102187 R 552526 CDS YP_002122494.1 195977250 6760629 103744..105030 1 NC_011134.1 similar to gb|ABA41499.1| collagen-like protein I [Streptococcus equi subsp. equi]; Possible adhesin, has a collagen-structural-motif domain composed of 83 Gly-Xaa-Yaa repeats that in part form 22 GDQ-GQK-GER repeats.; hypothetical protein 105030 sclZ.1 6760629 sclZ.1 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002122494.1 103744 D 552526 CDS YP_002122495.1 195977251 6762225 105157..106308 1 NC_011134.1 similar to gb|ABA41497.1| collagen-like protein G [Streptococcus equi subsp. equi]; Possible adhesin, has a collagen-structural-motif domain composed of 67 Gly-Xaa-Yaa repeats.; hypothetical protein 106308 sclZ.2 6762225 sclZ.2 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002122495.1 105157 D 552526 CDS YP_002122496.1 195977252 6760628 106820..107344 1 NC_011134.1 similar to ref|ZP_01372633.1| NUDIX hydrolase [Desulfitobacterium hafniense DCB-2]; Catalyzes The 1,3-Allylic Rearrangement Of The Homoallylic Substrate Isopentenyl (Ipp) To Its Highly Electrophilic Allylic Isomer, Dimethylallyl Diphosphate (Dmapp).; nudix hydrolase 107344 6760628 Sez_0101 Streptococcus equi subsp. zooepidemicus MGCS10565 nudix hydrolase YP_002122496.1 106820 D 552526 CDS YP_002122497.1 195977253 6762145 107558..108409 1 NC_011134.1 An essential enzyme in the nonmevalonate pathway of isopentenyl diphosphate and dimethylallyl diphosphate biosynthesis; 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase 108409 ipk 6762145 ipk Streptococcus equi subsp. zooepidemicus MGCS10565 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase YP_002122497.1 107558 D 552526 CDS YP_002122498.1 195977254 6760627 108479..108922 1 NC_011134.1 similar to ref|YP_059444.1| High-affinity zinc uptake system ATP-binding protein [Streptococcus pyogenes MGAS10394]; Unknown, COG1846 Transcriptional regulators.; transcriptional repressor AdcR for Zn(2+)-responsive expression 108922 adcR 6760627 adcR Streptococcus equi subsp. zooepidemicus MGCS10565 transcriptional repressor AdcR for Zn(2+)-responsive expression YP_002122498.1 108479 D 552526 CDS YP_002122499.1 195977255 6762252 108941..109645 1 NC_011134.1 similar to ref|YP_059444.1| High-affinity zinc uptake system ATP-binding protein [Streptococcus pyogenes MGAS10394]; Part of the ATP-driven transport system for zinc.; zinc ABC transporter ATP-binding protein ZnuC 109645 znuC 6762252 znuC Streptococcus equi subsp. zooepidemicus MGCS10565 zinc ABC transporter ATP-binding protein ZnuC YP_002122499.1 108941 D 552526 CDS YP_002122500.1 195977256 6760626 109614..110447 1 NC_011134.1 similar to ref|YP_279546.1| high-affinity zinc uptake system membrane protein [Streptococcus pyogenes MGAS6180]; Part of an ATP-driven transport system for zinc.; Zinc ABC transporter inner membrane permease ZnuB 110447 znuB 6760626 znuB Streptococcus equi subsp. zooepidemicus MGCS10565 Zinc ABC transporter inner membrane permease ZnuB YP_002122500.1 109614 D 552526 CDS YP_002122501.1 195977257 6760906 complement(110629..111885) 1 NC_011134.1 catalyzes the formation of tyrosyl-tRNA(Tyr) from tyrosine and tRNA(Tyr); tyrosyl-tRNA synthetase 111885 tyrS 6760906 tyrS Streptococcus equi subsp. zooepidemicus MGCS10565 tyrosyl-tRNA synthetase YP_002122501.1 110629 R 552526 CDS YP_002122502.1 195977258 6760625 111990..114290 1 NC_011134.1 similar to ref|NP_663878.1| penicillin-binding protein 1b [Streptococcus pyogenes MGAS315]; CSynthesis and cross-linking of nascent peptidoglycan glycan strands.; multimodular transpeptidase-transglycosylase 114290 pbpZ 6760625 pbpZ Streptococcus equi subsp. zooepidemicus MGCS10565 multimodular transpeptidase-transglycosylase YP_002122502.1 111990 D 552526 CDS YP_002122503.1 195977259 6762262 114552..118118 1 NC_011134.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme; DNA-directed RNA polymerase subunit beta 118118 rpoB 6762262 rpoB Streptococcus equi subsp. zooepidemicus MGCS10565 DNA-directed RNA polymerase subunit beta YP_002122503.1 114552 D 552526 CDS YP_002122504.1 195977260 6760624 118236..121844 1 NC_011134.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Subunit beta' binds to sigma factor allowing it to bind to the -10 region of the promoter; DNA-directed RNA polymerase subunit beta' 121844 rpoC 6760624 rpoC Streptococcus equi subsp. zooepidemicus MGCS10565 DNA-directed RNA polymerase subunit beta' YP_002122504.1 118236 D 552526 CDS YP_002122505.1 195977261 6762273 122411..122965 1 NC_011134.1 similar to ref|ZP_01803959.1| hypothetical protein CdifQ_04001361 [Clostridium difficile QCD-32g58]; Unknown, Gene is flanked 5' and 3' by a 51 nt direct repeat (aggagctagtcttagctccttttatcatgctaaaatcattagattaattgg) and small ORFs with similarity to IS1193D.; hypothetical protein 122965 6762273 Sez_0110 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002122505.1 122411 D 552526 CDS YP_002122506.1 195977262 6760623 123518..124576 1 NC_011134.1 similar to ref|NP_736373.1| hypothetical protein gbs1940 [Streptococcus agalactiae NEM316]; Alanine racemase catalyses the pyridoxal-dependent conversion of L-alanine into D-alanine, a key component of bacterial peptidoglycan.; alanine racemase 124576 alr 6760623 alr Streptococcus equi subsp. zooepidemicus MGCS10565 alanine racemase YP_002122506.1 123518 D 552526 CDS YP_002122507.1 195977263 6762246 124637..125002 1 NC_011134.1 similar to ref|NP_268497.1| DNA binding protein [Streptococcus pyogenes M1 GAS]; Unknown, COG4699: Uncharacterized protein conserved in bacteria.; hypothetical protein 125002 6762246 Sez_0112 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002122507.1 124637 D 552526 CDS YP_002122508.1 195977264 6760622 125535..127538 1 NC_011134.1 similar to ref|YP_001450417.1| bacteriocin-associated integral membrane protein subfamily [Streptococcus gordonii str. Challis substr. CH1]; Unknown, bacteriocin associated membrane protein; immunity protein.; immunity protein 127538 6760622 Sez_0113 Streptococcus equi subsp. zooepidemicus MGCS10565 immunity protein YP_002122508.1 125535 D 552526 CDS YP_002122509.1 195977265 6762242 127540..128208 1 NC_011134.1 similar to ref|ZP_01835894.1| ABC transporter, ATP-binding protein [Streptococcus pneumoniae SP23-BS72]; Probably part of a binding-protein-dependent transport system for an amino acid. Probably responsible for energy coupling to the transport system; competence damage-inducible protein A.; ABC transporter ATP-binding protein 128208 6762242 Sez_0114 Streptococcus equi subsp. zooepidemicus MGCS10565 ABC transporter ATP-binding protein YP_002122509.1 127540 D 552526 CDS YP_002122510.1 195977266 6760621 128366..129304 1 NC_011134.1 similar to ref|YP_595819.1| ComG operon protein 1 [Streptococcus pyogenes MGAS9429]; Required for uptake of DNA by competent cells.; late competence protein ComGA 129304 comGA 6760621 comGA Streptococcus equi subsp. zooepidemicus MGCS10565 late competence protein ComGA YP_002122510.1 128366 D 552526 CDS YP_002122511.1 195977267 6762248 129180..130271 1 NC_011134.1 similar to ref|YP_281451.1| comG operon protein 2 [Streptococcus pyogenes MGAS5005]; Required for transformation and DNA binding.; late competence protein ComGB 130271 comGB 6762248 comGB Streptococcus equi subsp. zooepidemicus MGCS10565 late competence protein ComGB YP_002122511.1 129180 D 552526 CDS YP_002122512.1 195977268 6760620 130272..130595 1 NC_011134.1 similar to ref|YP_601589.1| ComG operon protein 3 [Streptococcus pyogenes MGAS10750]; Involved in competence.; late competence protein ComGC 130595 comGC 6760620 comGC Streptococcus equi subsp. zooepidemicus MGCS10565 late competence protein ComGC YP_002122512.1 130272 D 552526 CDS YP_002122513.1 195977269 6760909 130573..130998 1 NC_011134.1 similar to ref|NP_663885.1| competence protein [Streptococcus pyogenes MGAS315]; Involved in competence.; late competence protein ComGD 130998 comGD 6760909 comGD Streptococcus equi subsp. zooepidemicus MGCS10565 late competence protein ComGD YP_002122513.1 130573 D 552526 CDS YP_002122514.1 195977270 6760619 131158..131667 1 NC_011134.1 similar to ref|YP_281455.1| comG operon protein 6 [Streptococcus pyogenes MGAS5005]; Involved in competence.; competence protein ComG 131667 comGF 6760619 comGF Streptococcus equi subsp. zooepidemicus MGCS10565 competence protein ComG YP_002122514.1 131158 D 552526 CDS YP_002122515.1 195977271 6762292 131645..132007 1 NC_011134.1 similar to ref|YP_059458.1| ComG operon protein 6 [Streptococcus pyogenes MGAS10394]; Involved in competence.; late competence protein ComGG 132007 comGF 6762292 comGF Streptococcus equi subsp. zooepidemicus MGCS10565 late competence protein ComGG YP_002122515.1 131645 D 552526 CDS YP_002122516.1 195977272 6760618 complement(132053..132856) 1 NC_011134.1 similar to ref|NP_268574.1| transposase, IS861 [Streptococcus pyogenes M1 GAS]; transposase IS861 orfB 132856 6760618 Sez_0121 Streptococcus equi subsp. zooepidemicus MGCS10565 transposase IS861 orfB YP_002122516.1 132053 R 552526 CDS YP_002122517.1 195977273 6762096 complement(132880..133395) 1 NC_011134.1 similar to ref|YP_602677.1| Transposase [Streptococcus pyogenes MGAS10750]; transposase IS861 orfA 133395 6762096 Sez_0122 Streptococcus equi subsp. zooepidemicus MGCS10565 transposase IS861 orfA YP_002122517.1 132880 R 552526 CDS YP_002122518.1 195977274 6760617 133501..134454 1 NC_011134.1 similar to ref|YP_595826.1| adenine-specific methyltransferase [Streptococcus pyogenes MGAS9429]; Unknown, COG0827 Adenine-specific DNA methylase.; adenine-specific methyltransferase 134454 6760617 Sez_0123 Streptococcus equi subsp. zooepidemicus MGCS10565 adenine-specific methyltransferase YP_002122518.1 133501 D 552526 CDS YP_002122519.1 195977275 6762257 134514..135716 1 NC_011134.1 AckA utilizes acetate and can acetylate CheY which increases signal strength during flagellar rotation; utilizes magnesium and ATP; also involved in conversion of acetate to aceyl-CoA; acetate kinase 135716 ackA 6762257 ackA Streptococcus equi subsp. zooepidemicus MGCS10565 acetate kinase YP_002122519.1 134514 D 552526 CDS YP_002122520.1 195977276 6760616 complement(136088..136702) 1 NC_011134.1 similar to ref|ZP_01817412.1| hypothetical protein CGSSp3BS71_02812 [Streptococcus pneumoniae SP3-BS71]; hypothetical protein 136702 6760616 Sez_0125 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002122520.1 136088 R 552526 CDS YP_002122521.1 195977277 6760914 137231..139273 1 NC_011134.1 similar to ref|ZP_00784694.1| transcriptional antiterminator, BglG family [Streptococcus agalactiae COH1]; Transcriptional antiterminator.; BglG family transcriptional regulator 139273 6760914 Sez_0126 Streptococcus equi subsp. zooepidemicus MGCS10565 BglG family transcriptional regulator YP_002122521.1 137231 D 552526 CDS YP_002122522.1 195977278 6760615 139275..139562 1 NC_011134.1 similar to ref|NP_687232.1| PTS system, IIB component, [Streptococcus agalactiae 2603V/R]; Probably involved in ascorbate uptake.; sugar phosphotransferase component II B 139562 6760615 Sez_0127 Streptococcus equi subsp. zooepidemicus MGCS10565 sugar phosphotransferase component II B YP_002122522.1 139275 D 552526 CDS YP_002122523.1 195977279 6760917 139575..140918 1 NC_011134.1 membrane component; functions with enzymes IIB (sgaB; ulaB) and IIA (sgaA; ulaC) enzyme I and HPr for anaerobic utilization and uptake of L-ascorbate; sgaTBA are regulated by yifQ as well as Crp and Fnr; PTS system ascorbate-specific transporter subunit IIC 140918 ulaA 6760917 ulaA Streptococcus equi subsp. zooepidemicus MGCS10565 PTS system ascorbate-specific transporter subunit IIC YP_002122523.1 139575 D 552526 CDS YP_002122524.1 195977280 6760913 142912..143034 1 NC_011134.1 hypothetical protein 143034 6760913 Sez_0131 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002122524.1 142912 D 552526 CDS YP_002122525.1 195977281 6760612 143257..145152 1 NC_011134.1 similar to ref|YP_597524.1| oligoendopeptidase O [Streptococcus pyogenes MGAS9429]; Unknown, COG3590 Predicted metalloendopeptidase.; metallopeptidase PepO 145152 pepO 6760612 pepO Streptococcus equi subsp. zooepidemicus MGCS10565 metallopeptidase PepO YP_002122525.1 143257 D 552526 CDS YP_002122526.1 195977282 6760912 complement(145352..146407) 1 NC_011134.1 EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu; elongation factor Ts 146407 tsf 6760912 tsf Streptococcus equi subsp. zooepidemicus MGCS10565 elongation factor Ts YP_002122526.1 145352 R 552526 CDS YP_002122527.1 195977283 6760611 complement(146560..147315) 1 NC_011134.1 one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit; 30S ribosomal protein S2 147315 rpsB 6760611 rpsB Streptococcus equi subsp. zooepidemicus MGCS10565 30S ribosomal protein S2 YP_002122527.1 146560 R 552526 CDS YP_002122528.1 195977284 6760610 complement(149343..149903) 1 NC_011134.1 similar to ref|NP_270011.1| alkyl hydroperoxidase [Streptococcus pyogenes M1 GAS]; Directly reduces organic hydroperoxides in its reduced dithiol form.; alkyl hydroperoxide reductase 149903 ahpC 6760610 ahpC Streptococcus equi subsp. zooepidemicus MGCS10565 alkyl hydroperoxide reductase YP_002122528.1 149343 R 552526 CDS YP_002122529.1 195977285 6760859 150535..150738 1 NC_011134.1 similar to ref|NP_270010.1| cold shock protein [Streptococcus pyogenes M1 GAS]; Stimulates the transcription of cold-shock-inducible promoters.; cold-shock protein 150738 cspA 6760859 cspA Streptococcus equi subsp. zooepidemicus MGCS10565 cold-shock protein YP_002122529.1 150535 D 552526 CDS YP_002122530.1 195977286 6760609 150910..151371 1 NC_011134.1 similar to ref|YP_599441.1| CtsR family transcriptional regulator [Streptococcus pyogenes MGAS10270]; Negative regulator of class III stress genes (clpC, clpP).; CtsR family transcriptional regulator 151371 ctsR 6760609 ctsR Streptococcus equi subsp. zooepidemicus MGCS10565 CtsR family transcriptional regulator YP_002122530.1 150910 D 552526 CDS YP_002122531.1 195977287 6760924 151392..153812 1 NC_011134.1 similar to ref|YP_603351.1| Negative regulator of genetic competence clpC/mecB [Streptococcus pyogenes MGAS10750]; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with dnaK, dnaJ and grpE. Acts before dnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of clpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by dnaK.; ATP-dependent Clp protease ATP-binding subunit 153812 clpC 6760924 clpC Streptococcus equi subsp. zooepidemicus MGCS10565 ATP-dependent Clp protease ATP-binding subunit YP_002122531.1 151392 D 552526 CDS YP_002122532.1 195977288 6760608 154581..155012 1 NC_011134.1 similar to ref|NP_688051.1| hypothetical protein SAG1041 [Streptococcus agalactiae 2603V/R]; hypothetical protein 155012 6760608 Sez_0141 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002122532.1 154581 D 552526 CDS YP_002122533.1 195977289 6760920 155044..156303 1 NC_011134.1 similar to ref|ZP_00874485.1| Lipase, class 3 [Streptococcus suis 89/1591]; Unknown, has lipase class 3 domain.; hypothetical protein 156303 6760920 Sez_0142 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002122533.1 155044 D 552526 CDS YP_002122534.1 195977290 6760607 156309..156677 1 NC_011134.1 similar to ref|ZP_00874484.1| hypothetical protein SsuiDRAFT_1541 [Streptococcus suis 89/1591]; hypothetical protein 156677 6760607 Sez_0143 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002122534.1 156309 D 552526 CDS YP_002122535.1 195977291 6762302 156658..156948 1 NC_011134.1 similar to ref|ZP_00874545.1| hypothetical protein SsuiDRAFT_1602 [Streptococcus suis 89/1591]; hypothetical protein 156948 6762302 Sez_0144 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002122535.1 156658 D 552526 CDS YP_002122536.1 195977292 6760606 157248..157535 1 NC_011134.1 10 kDa chaperonin; Cpn10; GroES; forms homoheptameric ring; binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it; folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES; release of the folded substrate is dependent on ATP binding and hydrolysis in the trans ring; co-chaperonin GroES 157535 groES 6760606 groES Streptococcus equi subsp. zooepidemicus MGCS10565 co-chaperonin GroES YP_002122536.1 157248 D 552526 CDS YP_002122537.1 195977293 6760931 157603..159228 1 NC_011134.1 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth; molecular chaperone GroEL 159228 groEL 6760931 groEL Streptococcus equi subsp. zooepidemicus MGCS10565 molecular chaperone GroEL YP_002122537.1 157603 D 552526 CDS YP_002122538.1 195977294 6760605 complement(159562..160032) 1 NC_011134.1 similar to ref|YP_001450297.1| Phosphohydrolase (MutT/nudix family protein) [Streptococcus gordonii str. Challis substr. CH1]; MutT/nudix family protein 160032 6760605 Sez_0147 Streptococcus equi subsp. zooepidemicus MGCS10565 MutT/nudix family protein YP_002122538.1 159562 R 552526 CDS YP_002122539.1 195977295 6760934 160339..160665 1 NC_011134.1 similar to ref|ZP_01824093.1| hypothetical protein CGSSp9BS68_00132 [Streptococcus pneumoniae SP9-BS68]; hypothetical protein 160665 6760934 Sez_0148 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002122539.1 160339 D 552526 CDS YP_002122540.1 195977296 6760604 160675..161814 1 NC_011134.1 similar to ref|ZP_01824094.1| hypothetical protein CGSSp9BS68_00137 [Streptococcus pneumoniae SP9-BS68]; hypothetical protein 161814 6760604 Sez_0149 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002122540.1 160675 D 552526 CDS YP_002122541.1 195977297 6762322 162290..162877 1 NC_011134.1 similar to ref|ZP_01824096.1| ATPase [Streptococcus pneumoniae SP9-BS68]; Part ABC transporter complex.; Nod factor export ATP-binding protein I (Nodulation ATP-binding protein I) 162877 6762322 Sez_0150 Streptococcus equi subsp. zooepidemicus MGCS10565 Nod factor export ATP-binding protein I (Nodulation ATP-binding protein I) YP_002122541.1 162290 D 552526 CDS YP_002122542.1 195977298 6760603 162874..163356 1 NC_011134.1 similar to ref|ZP_01819232.1| hypothetical protein CGSSp6BS73_09666 [Streptococcus pneumoniae SP6-BS73]; hypothetical protein 163356 6760603 Sez_0151 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002122542.1 162874 D 552526 CDS YP_002122543.1 195977299 6762327 163381..163896 1 NC_011134.1 similar to ref|ZP_01819367.1| succinyl-diaminopimelate desuccinylase [Streptococcus pneumoniae SP6-BS73]; hypothetical protein 163896 6762327 Sez_0152 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002122543.1 163381 D 552526 CDS YP_002122544.1 195977300 6760602 164530..166164 1 NC_011134.1 similar to ref|NP_608080.1| hypothetical protein spyM18_2125 [Streptococcus pyogenes MGAS8232]; hypothetical protein 166164 6760602 Sez_0153 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002122544.1 164530 D 552526 CDS YP_002122545.1 195977301 6760932 complement(166305..167198) 1 NC_011134.1 similar to ref|NP_722253.1| pseudouridylate synthase [Streptococcus mutans UA159]; Responsible For Synthesis Of Pseudouridine From Uracil At Positions 955, 2504 And 2580 In 23s Ribosomal RNA.; ribosomal large subunit pseudouridine synthase D 167198 yhcT 6760932 yhcT Streptococcus equi subsp. zooepidemicus MGCS10565 ribosomal large subunit pseudouridine synthase D YP_002122545.1 166305 R 552526 CDS YP_002122546.1 195977302 6760601 complement(167182..167379) 1 NC_011134.1 similar to ref|NP_665564.1| hypothetical protein SpyM3_1760 [Streptococcus pyogenes MGAS315]; hypothetical protein 167379 6760601 Sez_0155 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002122546.1 167182 R 552526 CDS YP_002122547.1 195977303 6760928 167608..169350 1 NC_011134.1 similar to ref|NP_688485.1| hypothetical protein SAG1491 [Streptococcus agalactiae 2603V/R]; S-layer protein 169350 6760928 Sez_0156 Streptococcus equi subsp. zooepidemicus MGCS10565 S-layer protein YP_002122547.1 167608 D 552526 CDS YP_002122548.1 195977304 6760600 169491..169871 1 NC_011134.1 similar to ref|ZP_00365970.1| COG0251: translation initiation inhibitor, yjgF family [Streptococcus pyogenes M49 591]; translation initiation inhibitor 169871 6760600 Sez_0157 Streptococcus equi subsp. zooepidemicus MGCS10565 translation initiation inhibitor YP_002122548.1 169491 D 552526 CDS YP_002122549.1 195977305 6760938 169909..172230 1 NC_011134.1 similar to ref|YP_061071.1| Multimodular transpeptidase-transglycosylase PBP 2A [Streptococcus pyogenes MGAS10394]; Cell wall formation. May be involved in outgrowth of the germinated spore or it could function in the synthesis of the germ cell wall.; multimodular transpeptidase-transglycosylase 172230 6760938 Sez_0158 Streptococcus equi subsp. zooepidemicus MGCS10565 multimodular transpeptidase-transglycosylase YP_002122549.1 169909 D 552526 CDS YP_002122550.1 195977306 6760598 172443..172619 1 NC_011134.1 forms a complex with SecY and SecG; SecYEG forms a protein-conducting channel to which secA binds and translocates targeted polypeptides across the cytoplasmic membrane, a process driven by ATP and a proton-motive force; preprotein translocase subunit SecE 172619 secE 6760598 secE Streptococcus equi subsp. zooepidemicus MGCS10565 preprotein translocase subunit SecE YP_002122550.1 172443 D 552526 CDS YP_002122551.1 195977307 6762279 173010..173555 1 NC_011134.1 Modulates Rho-dependent transcription termination; transcription antitermination protein NusG 173555 nusG 6762279 nusG Streptococcus equi subsp. zooepidemicus MGCS10565 transcription antitermination protein NusG YP_002122551.1 173010 D 552526 CDS YP_002122552.1 195977308 6760599 complement(173544..173666) 1 NC_011134.1 hypothetical protein 173666 6760599 Sez_0161 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002122552.1 173544 R 552526 CDS YP_002122553.1 195977309 6762288 174028..175035 1 NC_011134.1 similar to gb|ABA41496.1| collagen-like protein F [Streptococcus equi subsp. equi]; Possible adhesin, has a collagen-structural-motif domain composed of 55 Gly-Xaa-Yaa repeats.; hypothetical protein 175035 sclZ.3 6762288 sclZ.3 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002122553.1 174028 D 552526 CDS YP_002122554.1 195977310 6760597 175795..177312 1 NC_011134.1 similar to emb|CAB65412.1| Mga-like regulatory protein [Streptococcus dysgalactiae subsp. dysgalactiae]; positive regulator of the adjacent M-like protein.; M protein trans-acting positive regulator 177312 mgaZ 6760597 mgaZ Streptococcus equi subsp. zooepidemicus MGCS10565 M protein trans-acting positive regulator YP_002122554.1 175795 D 552526 CDS YP_002122555.1 195977311 6760937 177487..178665 1 NC_011134.1 similar to gb|AAB71984.1| M-protein [Streptococcus equi]; Binds IgG molecules of the Ig1, Ig2 and Ig4 subclasses, and also binds fibrinogen.; protective antigen-like protein, fibrinogen- and Ig-binding protein precursor 178665 spaZ 6760937 spaZ Streptococcus equi subsp. zooepidemicus MGCS10565 protective antigen-like protein, fibrinogen- and Ig-binding protein precursor YP_002122555.1 177487 D 552526 CDS YP_002122556.1 195977312 6760596 complement(178713..178874) 1 NC_011134.1 hypothetical protein 178874 6760596 Sez_0165 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002122556.1 178713 R 552526 CDS YP_002122557.1 195977313 6760936 179254..181755 1 NC_011134.1 leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase; leucyl-tRNA synthetase 181755 leuS 6760936 leuS Streptococcus equi subsp. zooepidemicus MGCS10565 leucyl-tRNA synthetase YP_002122557.1 179254 D 552526 CDS YP_002122558.1 195977314 6760595 181942..182286 1 NC_011134.1 similar to ref|NP_268734.1| hypothetical protein SPy_0435 [Streptococcus pyogenes M1 GAS]; hypothetical protein 182286 6760595 Sez_0167 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002122558.1 181942 D 552526 CDS YP_002122559.1 195977315 6762285 182494..183927 1 NC_011134.1 membrane component; functions with enzymes IIB (sgaB; ulaB) and IIA (sgaA; ulaC) enzyme I and HPr for anaerobic utilization and uptake of L-ascorbate; sgaTBA are regulated by yifQ as well as Crp and Fnr; PTS system ascorbate-specific transporter subunit IIC 183927 ulaA 6762285 ulaA Streptococcus equi subsp. zooepidemicus MGCS10565 PTS system ascorbate-specific transporter subunit IIC YP_002122559.1 182494 D 552526 CDS YP_002122560.1 195977316 6760594 184043..184321 1 NC_011134.1 similar to ref|NP_268554.1| hypothetical protein SPy_0175 [Streptococcus pyogenes M1 GAS]; The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. This system is involved in ascorbate transport.; PTS system 3-keto-L-gulonate/L-ascorbate specific transporter subunit IIB (SgaB) 184321 sgaB 6760594 sgaB Streptococcus equi subsp. zooepidemicus MGCS10565 PTS system 3-keto-L-gulonate/L-ascorbate specific transporter subunit IIB (SgaB) YP_002122560.1 184043 D 552526 CDS YP_002122561.1 195977317 6760940 184538..185023 1 NC_011134.1 similar to ref|YP_601650.1| PTS system, 3-keto-L-gulonate specific IIA component [Streptococcus pyogenes MGAS10750]; The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. This system is involved in ascorbate transport.; ascorbate-specific phosphotransferase enzyme IIA component 185023 sgaC 6760940 sgaC Streptococcus equi subsp. zooepidemicus MGCS10565 ascorbate-specific phosphotransferase enzyme IIA component YP_002122561.1 184538 D 552526 CDS YP_002122562.1 195977318 6760593 185121..185783 1 NC_011134.1 catalyzes the formation of L-xylulose-5-phosphate from 3-keto-L-gulonate-6-phosphate in anaerobic L-ascorbate utilization; 3-keto-L-gulonate-6-phosphate decarboxylase 185783 ulaD 6760593 ulaD Streptococcus equi subsp. zooepidemicus MGCS10565 3-keto-L-gulonate-6-phosphate decarboxylase YP_002122562.1 185121 D 552526 CDS YP_002122563.1 195977319 6760916 185683..186651 1 NC_011134.1 L-xylulose 5-phosphate 3-epimerase activity not yet demonstrated; may be involved in the utilization of 2,3-diketo-L-gulonate; L-xylulose 5-phosphate 3-epimerase 186651 sgaU 6760916 sgaU Streptococcus equi subsp. zooepidemicus MGCS10565 L-xylulose 5-phosphate 3-epimerase YP_002122563.1 185683 D 552526 CDS YP_002122564.1 195977320 6760592 186652..187368 1 NC_011134.1 catalyzes the formation of D-xylulose 5-phosphate from L-ribulose 5-phosphate in the L-arabinose and L-ascorbate degradation pathways; L-ribulose-5-phosphate 4-epimerase 187368 araD 6760592 araD Streptococcus equi subsp. zooepidemicus MGCS10565 L-ribulose-5-phosphate 4-epimerase YP_002122564.1 186652 D 552526 CDS YP_002122565.1 195977321 6760943 187665..189317 1 NC_011134.1 similar to ref|YP_059519.1| Transcription antiterminator, BglG family [Streptococcus pyogenes MGAS10394]; regulator of adjacent sga operon.; transcriptional antiterminator with PTS regulation domain 189317 6760943 Sez_0174 Streptococcus equi subsp. zooepidemicus MGCS10565 transcriptional antiterminator with PTS regulation domain YP_002122565.1 187665 D 552526 CDS YP_002122566.1 195977322 6760591 189512..190603 1 NC_011134.1 similar to ref|YP_601656.1| L-ascorbate 6-phosphate lactonase [Streptococcus pyogenes MGAS10750]; Proposed to catalyze the first step in L-ascorbate-6-phosphate degradation.; L-ascorbate 6-phosphate lactonase 190603 sgaG 6760591 sgaG Streptococcus equi subsp. zooepidemicus MGCS10565 L-ascorbate 6-phosphate lactonase YP_002122566.1 189512 D 552526 CDS YP_002122567.1 195977323 6760942 190738..190914 1 NC_011134.1 hypothetical protein 190914 6760942 Sez_0176 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002122567.1 190738 D 552526 CDS YP_002122568.1 195977324 6760589 191114..192310 1 NC_011134.1 similar to ref|NP_268562.1| glycine betaine/proline ABC transporter (ATP-binding protein) [Streptococcus pyogenes M1 GAS]; Involved in a multicomponent binding-protein-dependent transport system for glycine betaine. Probably responsible for energy coupling to the transport system.; glycine betaine transport ATP-binding protein OpuAA 192310 opuAA 6760589 opuAA Streptococcus equi subsp. zooepidemicus MGCS10565 glycine betaine transport ATP-binding protein OpuAA YP_002122568.1 191114 D 552526 CDS YP_002122569.1 195977325 6760951 192328..194058 1 NC_011134.1 similar to ref|YP_601658.1| Glycine betaine-binding protein / Glycine betaine transport system permease [Streptococcus pyogenes MGAS10750]; Involved in a multicomponent binding-protein-dependent transport system for glycine betaine; probably responsible for the translocation of the substrate across the membrane.; glycine betaine transport system permease OpuAB 194058 opuAB 6760951 opuAB Streptococcus equi subsp. zooepidemicus MGCS10565 glycine betaine transport system permease OpuAB YP_002122569.1 192328 D 552526 CDS YP_002122570.1 195977326 6760588 complement(194284..194433) 1 NC_011134.1 hypothetical protein 194433 6760588 Sez_0179 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002122570.1 194284 R 552526 CDS YP_002122571.1 195977327 6762308 194597..196318 1 NC_011134.1 similar to ref|ZP_01371554.1| transposase, IS4 [Desulfitobacterium hafniense DCB-2]; transposase IS4-like 196318 6762308 Sez_0180 Streptococcus equi subsp. zooepidemicus MGCS10565 transposase IS4-like YP_002122571.1 194597 D 552526 CDS YP_002122572.1 195977328 6760587 complement(196423..196572) 1 NC_011134.1 hypothetical protein 196572 6760587 Sez_0181 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002122572.1 196423 R 552526 CDS YP_002122573.1 195977329 6760950 196567..199266 1 NC_011134.1 has 3'-5' exonuclease, 5'-3' exonuclease and 5'-3'polymerase activities, primarily functions to fill gaps during DNA replication and repair; DNA polymerase I 199266 polA 6760950 polA Streptococcus equi subsp. zooepidemicus MGCS10565 DNA polymerase I YP_002122573.1 196567 D 552526 CDS YP_002122574.1 195977330 6760586 199687..200139 1 NC_011134.1 similar to ref|YP_597771.1| CoA binding protein [Streptococcus pyogenes MGAS10270]; Unknown, COG1832 Predicted CoA-binding protein.; succinyl-CoA synthetase subunit alpha 200139 6760586 Sez_0183 Streptococcus equi subsp. zooepidemicus MGCS10565 succinyl-CoA synthetase subunit alpha YP_002122574.1 199687 D 552526 CDS YP_002122575.1 195977331 6760947 200176..200649 1 NC_011134.1 similar to ref|YP_279628.1| ferric uptake regulation protein [Streptococcus pyogenes MGAS6180]; Regulation of ferric uptake.; Ferric uptake regulator Fur 200649 furR 6760947 furR Streptococcus equi subsp. zooepidemicus MGCS10565 Ferric uptake regulator Fur YP_002122575.1 200176 D 552526 CDS YP_002122576.1 195977332 6760584 201010..202689 1 NC_011134.1 immunoglobulin G binding protein G precursor; similar to gb|AAQ08491.1| Szp protein [Streptococcus equi subsp. zooepidemicus]; Unknown, possibly involved in immune evasion; antiphagocytic M-like protein 202689 6760584 Sez_0185 Streptococcus equi subsp. zooepidemicus MGCS10565 antiphagocytic M-like protein YP_002122576.1 201010 D 552526 CDS YP_002122577.1 195977333 6760949 202803..206783 1 NC_011134.1 similar to dbj|BAF34922.1| dextran-binding lectin A [Streptococcus sobrinus]; Catalysis of the hydrolysis of terminal, non-reducing alpha-D-galactose residues in alpha-D-galactosides, including galactose oligosaccharides, galactomannans and galactohydrolase.; alpha-galactosidase 206783 6760949 Sez_0186 Streptococcus equi subsp. zooepidemicus MGCS10565 alpha-galactosidase YP_002122577.1 202803 D 552526 CDS YP_002122578.1 195977334 6760582 complement(206978..207823) 1 NC_011134.1 similar to ref|ZP_00365478.1| COG5523: Predicted integral membrane protein [Streptococcus pyogenes M49 591]; hypothetical protein 207823 6760582 Sez_0187 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002122578.1 206978 R 552526 CDS YP_002122579.1 195977335 6760921 complement(207856..207999) 1 NC_011134.1 hypothetical protein 207999 6760921 Sez_0188 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002122579.1 207856 R 552526 CDS YP_002122580.1 195977336 6760581 207978..209186 1 NC_011134.1 Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr); queuine tRNA-ribosyltransferase 209186 tgt 6760581 tgt Streptococcus equi subsp. zooepidemicus MGCS10565 queuine tRNA-ribosyltransferase YP_002122580.1 207978 D 552526 CDS YP_002122581.1 195977337 6760953 209617..211005 1 NC_011134.1 similar to gb|AAQ91576.1| collagen-like protein 3 [Streptococcus equi]; Specific Function:Possible adhesin, has a collagen-structural-motif domain composed of 79 Gly-Xaa-Yaa repeats.; hypothetical protein 211005 sclZ.4 6760953 sclZ.4 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002122581.1 209617 D 552526 CDS YP_002122582.1 195977338 6760580 212394..212705 1 NC_011134.1 similar to ref|YP_281540.1| zinc finger protein [Streptococcus pyogenes MGAS5005]; zinc finger protein 212705 6760580 Sez_0191 Streptococcus equi subsp. zooepidemicus MGCS10565 zinc finger protein YP_002122582.1 212394 D 552526 CDS YP_002122583.1 195977339 6760955 212709..213248 1 NC_011134.1 similar to ref|YP_059530.1| BioY [Streptococcus pyogenes MGAS10394]; BioY family protein 213248 bioY 6760955 bioY Streptococcus equi subsp. zooepidemicus MGCS10565 BioY family protein YP_002122583.1 212709 D 552526 CDS YP_002122584.1 195977340 6760579 213329..214129 1 NC_011134.1 similar to ref|YP_059531.1| Metal-dependent hydrolase [Streptococcus pyogenes MGAS10394]; metal-dependent hydrolase 214129 6760579 Sez_0193 Streptococcus equi subsp. zooepidemicus MGCS10565 metal-dependent hydrolase YP_002122584.1 213329 D 552526 CDS YP_002122585.1 195977341 6762144 214126..214620 1 NC_011134.1 similar to ref|YP_001127758.1| deaminase [Streptococcus pyogenes str. Manfredo]; tRNA-specific adenosine-34 deaminase 214620 6762144 Sez_0194 Streptococcus equi subsp. zooepidemicus MGCS10565 tRNA-specific adenosine-34 deaminase YP_002122585.1 214126 D 552526 CDS YP_002122586.1 195977342 6760578 complement(214730..215980) 1 NC_011134.1 similar to ref|YP_601669.1| S-layer protein / Peptidoglycan endo-beta-N-acetylglucosaminidase [Streptococcus pyogenes MGAS10750]; S-layer protein 215980 6760578 Sez_0195 Streptococcus equi subsp. zooepidemicus MGCS10565 S-layer protein YP_002122586.1 214730 R 552526 CDS YP_002122587.1 195977343 6762139 complement(216089..217042) 1 NC_011134.1 similar to ref|ZP_00874436.1| Integrase, catalytic region [Streptococcus suis 89/1591]; transposase IS1239 217042 6762139 Sez_0196 Streptococcus equi subsp. zooepidemicus MGCS10565 transposase IS1239 YP_002122587.1 216089 R 552526 CDS YP_002122588.1 195977344 6760577 217373..217969 1 NC_011134.1 similar to emb|CAD33903.1| hypothethical protein [Streptococcus dysgalactiae subsp. equisimilis]; hypothetical protein 217969 6760577 Sez_0197 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002122588.1 217373 D 552526 CDS YP_002122589.1 195977345 6762167 complement(218113..218238) 1 NC_011134.1 hypothetical protein 218238 6762167 Sez_0198 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002122589.1 218113 R 552526 CDS YP_002122590.1 195977346 6760576 218366..219619 1 NC_011134.1 similar to gb|AAQ03572.1|AF414053_1 hyaluronan synthase [Streptococcus equi subsp. zooepidemicus]; Glycosaminoglycan synthesis. The hyaluronic acid capsule is involved in the pathogenicity of group A Streptococci; it may be the major virulence determinant.; hyaluronan synthase HasA 219619 hasA 6760576 hasA Streptococcus equi subsp. zooepidemicus MGCS10565 hyaluronan synthase HasA YP_002122590.1 218366 D 552526 CDS YP_002122591.1 195977347 6762216 219878..221083 1 NC_011134.1 similar to gb|AAN65249.1|AF347022_2 UDP-glucose dehydrogenase [Streptococcus equi subsp. zooepidemicus]; Catalyzes the formation of UDP-glucuronic acid which is required for capsular hyaluronic acid synthesis.; UDP-glucose 6-dehydrogenase HasB 221083 hasB 6762216 hasB Streptococcus equi subsp. zooepidemicus MGCS10565 UDP-glucose 6-dehydrogenase HasB YP_002122591.1 219878 D 552526 CDS YP_002122592.1 195977348 6760575 221133..222035 1 NC_011134.1 similar to gb|AAN65250.1|AF347022_3 UDP-glucose pyrophosphorylase [Streptococcus equi subsp. zooepidemicus]; May play a role in stationary phase survival.; UTP-glucose-1-phosphate uridylyltransferase 222035 hasC.1 6760575 hasC.1 Streptococcus equi subsp. zooepidemicus MGCS10565 UTP-glucose-1-phosphate uridylyltransferase YP_002122592.1 221133 D 552526 CDS YP_002122593.1 195977349 6762135 222202..223581 1 NC_011134.1 similar to gb|AAQ05206.1|AF468690_1 UDP-N-acetyl-glucosamine pyrophosphorylase [Streptococcus equi subsp. zooepidemicus]; Bifunctional Enzyme Responsible For The Acetylation Of Glc-N-1-P To Give Glcnac-1-P And The Synthesis Of UDP-Glcnac.; bifunctional N-acetylglucosamine-1-phosphate uridyltransferase / glucosamine-1-phosphate N-acetyltransferase GlmU 223581 glmU 6762135 glmU Streptococcus equi subsp. zooepidemicus MGCS10565 bifunctional N-acetylglucosamine-1-phosphate uridyltransferase / glucosamine-1-phosphate N-acetyltransferase GlmU YP_002122593.1 222202 D 552526 CDS YP_002122594.1 195977350 6760574 223758..225107 1 NC_011134.1 functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis; catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate; member of PGI family; glucose-6-phosphate isomerase 225107 pgi 6760574 pgi Streptococcus equi subsp. zooepidemicus MGCS10565 glucose-6-phosphate isomerase YP_002122594.1 223758 D 552526 CDS YP_002122595.1 195977351 6762119 225693..226493 1 NC_011134.1 Converts D-sorbitol-dphosphate to D-fructose-6-phosphate; sorbitol-6-phosphate 2-dehydrogenase 226493 sorD 6762119 sorD Streptococcus equi subsp. zooepidemicus MGCS10565 sorbitol-6-phosphate 2-dehydrogenase YP_002122595.1 225693 D 552526 CDS YP_002122596.1 195977352 6760571 226516..228384 1 NC_011134.1 similar to ref|NP_720766.1| regulator of sorbitol operon [Streptococcus mutans UA159]; Positive regulator of sorbitol operon.; sorbitol operon transcription regulator SrlM 228384 srlM 6760571 srlM Streptococcus equi subsp. zooepidemicus MGCS10565 sorbitol operon transcription regulator SrlM YP_002122596.1 226516 D 552526 CDS YP_002122597.1 195977353 6762054 228393..228845 1 NC_011134.1 similar to ref|NP_720767.1| sorbitol operon activator [Streptococcus mutans UA159]; Positive regulator for sorbitol operon expression.; sorbitol operon activator SrlR 228845 srlR 6762054 srlR Streptococcus equi subsp. zooepidemicus MGCS10565 sorbitol operon activator SrlR YP_002122597.1 228393 D 552526 CDS YP_002122598.1 195977354 6760570 228993..229538 1 NC_011134.1 similar to ref|NP_720768.1| PTS system, sorbitol (glucitol) phosphotransferase enzyme IIC2 [Streptococcus mutans UA159]; The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. This system is involved in glucitol/sorbitol transport.; glucitol/sorbitol permease IIC component SrlA 229538 srlA 6760570 srlA Streptococcus equi subsp. zooepidemicus MGCS10565 glucitol/sorbitol permease IIC component SrlA YP_002122598.1 228993 D 552526 CDS YP_002122599.1 195977355 6762045 229551..230543 1 NC_011134.1 similar to ref|NP_720769.1| PTS system, sorbitol phosphotransferase enzyme IIBC [Streptococcus mutans UA159]; The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. This system is involved in glucitol/sorbitol transport.; PTS system glucitol/sorbitol-specific transporter subunit IIBC 230543 srlE 6762045 srlE Streptococcus equi subsp. zooepidemicus MGCS10565 PTS system glucitol/sorbitol-specific transporter subunit IIBC YP_002122599.1 229551 D 552526 CDS YP_002122600.1 195977356 6760569 230631..230942 1 NC_011134.1 similar to ref|NP_720770.1| PTS system, sorbitol-specific enzyme IIA [Streptococcus mutans UA159]; The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. This system is involved in glucitol/sorbitol transport.; Glucitol/sorbitol-specific phosphotransferase enzyme IIA component SrlB 230942 srlB 6760569 srlB Streptococcus equi subsp. zooepidemicus MGCS10565 Glucitol/sorbitol-specific phosphotransferase enzyme IIA component SrlB YP_002122600.1 230631 D 552526 CDS YP_002122601.1 195977357 6761995 231454..232884 1 NC_011134.1 similar to ref|ZP_02184619.1| cassette chromosome recombinase B1 [Carnobacterium sp. AT7]; transposase IS663-like 232884 6761995 Sez_0210 Streptococcus equi subsp. zooepidemicus MGCS10565 transposase IS663-like YP_002122601.1 231454 D 552526 CDS YP_002122602.1 195977358 6760568 233037..234323 1 NC_011134.1 similar to ref|ZP_00513513.1| abortive infection protein, [Crocosphaera watsonii WH8501]; abortive phage resistance protein 234323 6760568 Sez_0211 Streptococcus equi subsp. zooepidemicus MGCS10565 abortive phage resistance protein YP_002122602.1 233037 D 552526 CDS YP_002122603.1 195977359 6761929 234330..234965 1 NC_011134.1 similar to ref|ZP_01628459.1| hypothetical protein N9414_15200 [Nodularia spumigena CCY9414]; abortive phage resistance protein 234965 6761929 Sez_0212 Streptococcus equi subsp. zooepidemicus MGCS10565 abortive phage resistance protein YP_002122603.1 234330 D 552526 CDS YP_002122604.1 195977360 6760567 complement(235389..236399) 1 NC_011134.1 similar to gb|AAQ91579.1| collagen-like protein 3 [Streptococcus equi]; Possible adhesin, has a collagen-structural-motif domain composed of 61 Gly-Xaa-Yaa repeats.; hypothetical protein 236399 sclZ.5 6760567 sclZ.5 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002122604.1 235389 R 552526 CDS YP_002122605.1 195977361 6761868 237046..237579 1 NC_011134.1 similar to ref|YP_821136.1| 5-formyltetrahydrofolate cyclo-ligase [Streptococcus thermophilus LMD-9]; Catalysis of the reaction: ATP + 5-formyltetrahydrofolate = ADP + phosphate + 5,10-methenyltetrahydrofolate.; 5-formyltetrahydrofolate cyclo-ligase 237579 6761868 Sez_0214 Streptococcus equi subsp. zooepidemicus MGCS10565 5-formyltetrahydrofolate cyclo-ligase YP_002122605.1 237046 D 552526 CDS YP_002122606.1 195977362 6760566 237576..238259 1 NC_011134.1 similar to ref|YP_059541.1| integral membrane protein (Rhomboid family) [Streptococcus pyogenes MGAS10394]; hypothetical protein 238259 6760566 Sez_0215 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002122606.1 237576 D 552526 CDS YP_002122607.1 195977363 6761859 complement(238548..239516) 1 NC_011134.1 similar to gb|AAQ05209.1|AF468691_2 UDP-glucose pyrophosphorylase [Streptococcus equi subsp. zooepidemicus]; Catalysis of the reaction: UTP + alpha-D-glucose 1-phosphate = diphosphate + UDP-glucose.; UTP-glucose-1-phosphate uridylyltransferase 239516 hasC.2 6761859 hasC.2 Streptococcus equi subsp. zooepidemicus MGCS10565 UTP-glucose-1-phosphate uridylyltransferase YP_002122607.1 238548 R 552526 CDS YP_002122608.1 195977364 6760565 complement(239482..240501) 1 NC_011134.1 catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate; NAD(P)H-dependent glycerol-3-phosphate dehydrogenase 240501 gpsA 6760565 gpsA Streptococcus equi subsp. zooepidemicus MGCS10565 NAD(P)H-dependent glycerol-3-phosphate dehydrogenase YP_002122608.1 239482 R 552526 CDS YP_002122609.1 195977365 6761823 complement(240580..240717) 1 NC_011134.1 hypothetical protein 240717 6761823 Sez_0218 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002122609.1 240580 R 552526 CDS YP_002122610.1 195977366 6760564 240711..241160 1 NC_011134.1 similar to ref|YP_599803.1| Transcriptional regulator, MarR family [Streptococcus pyogenes MGAS2096]; MarR family transcriptional regulator 241160 6760564 Sez_0219 Streptococcus equi subsp. zooepidemicus MGCS10565 MarR family transcriptional regulator YP_002122610.1 240711 D 552526 CDS YP_002122611.1 195977367 6761806 241153..242862 1 NC_011134.1 similar to ref|YP_001127771.1| ABC transporter ATP-binding membrane protein [Streptococcus pyogenes str. Manfredo]; multidrug resistance ABC transporter ATP-binding protein/permease 242862 6761806 Sez_0220 Streptococcus equi subsp. zooepidemicus MGCS10565 multidrug resistance ABC transporter ATP-binding protein/permease YP_002122611.1 241153 D 552526 CDS YP_002122612.1 195977368 6760563 242862..244658 1 NC_011134.1 similar to ref|NP_268592.1| ABC transporter (ATP-binding protein) [Streptococcus pyogenes M1 GAS]; multidrug resistance ABC transporter ATP-binding protein/permease 244658 6760563 Sez_0221 Streptococcus equi subsp. zooepidemicus MGCS10565 multidrug resistance ABC transporter ATP-binding protein/permease YP_002122612.1 242862 D 552526 CDS YP_002122613.1 195977369 6761675 244820..245587 1 NC_011134.1 similar to ref|NP_663969.1| hypothetical protein SpyM3_0165 [Streptococcus pyogenes MGAS315]; Possibly invovlved in DNA integration/recombination/invertion.; hypothetical protein 245587 6761675 Sez_0222 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002122613.1 244820 D 552526 CDS YP_002122614.1 195977370 6760562 245767..246213 1 NC_011134.1 catalyzes the formation of dUMP from dUTP; deoxyuridine 5'-triphosphate nucleotidohydrolase 246213 dut 6760562 dut Streptococcus equi subsp. zooepidemicus MGCS10565 deoxyuridine 5'-triphosphate nucleotidohydrolase YP_002122614.1 245767 D 552526 CDS YP_002122615.1 195977371 6761723 246279..247640 1 NC_011134.1 Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents; DNA repair protein RadA 247640 radA 6761723 radA Streptococcus equi subsp. zooepidemicus MGCS10565 DNA repair protein RadA YP_002122615.1 246279 D 552526 CDS YP_002122616.1 195977372 6760561 248407..248913 1 NC_011134.1 similar to ref|YP_821127.1| Carbonic anhydrase [Streptococcus thermophilus LMD-9]; Carbonate hydro-lyase (carbon-dioxide-forming).; carbonic anhydrase 248913 6760561 Sez_0225 Streptococcus equi subsp. zooepidemicus MGCS10565 carbonic anhydrase YP_002122616.1 248407 D 552526 CDS YP_002122617.1 195977373 6761557 249041..249754 1 NC_011134.1 similar to ref|YP_279665.1| hypothetical protein M28_Spy0196 [Streptococcus pyogenes MGAS6180]; HTH DNA-binding protein 249754 6761557 Sez_0226 Streptococcus equi subsp. zooepidemicus MGCS10565 HTH DNA-binding protein YP_002122617.1 249041 D 552526 CDS YP_002122618.1 195977374 6760560 250356..251801 1 NC_011134.1 Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation; glutamyl-tRNA synthetase 251801 gltX 6760560 gltX Streptococcus equi subsp. zooepidemicus MGCS10565 glutamyl-tRNA synthetase YP_002122618.1 250356 D 552526 CDS YP_002122619.1 195977375 6761607 252244..253590 1 NC_011134.1 similar to ref|YP_597813.1| Sensory transduction protein kinase FasB [Streptococcus pyogenes MGAS10270]; sensory transduction protein kinase FasB 253590 fasB 6761607 fasB Streptococcus equi subsp. zooepidemicus MGCS10565 sensory transduction protein kinase FasB YP_002122619.1 252244 D 552526 CDS YP_002122620.1 195977376 6760558 253602..254900 1 NC_011134.1 similar to ref|YP_597814.1| Sensory transduction protein kinase FasC [Streptococcus pyogenes MGAS10270]; sensory transduction protein kinase FasC 254900 fasC 6760558 fasC Streptococcus equi subsp. zooepidemicus MGCS10565 sensory transduction protein kinase FasC YP_002122620.1 253602 D 552526 CDS YP_002122621.1 195977377 6761560 254904..255644 1 NC_011134.1 similar to gb|AAL78045.1| response regulator FasA [Streptococcus dysgalactiae subsp. equisimilis]; response regulator FasA 255644 fasA 6761560 fasA Streptococcus equi subsp. zooepidemicus MGCS10565 response regulator FasA YP_002122621.1 254904 D 552526 CDS YP_002122622.1 195977378 6760557 256477..256686 1 NC_011134.1 hypothetical protein 256686 6760557 Sez_0231 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002122622.1 256477 D 552526 CDS YP_002122623.1 195977379 6761501 256836..257543 1 NC_011134.1 similar to ref|NP_816714.1| ABC transporter, ATP-binding protein [Enterococcus faecalis V583]; Involved in transport.; ABC transporter ATP-binding protein 257543 6761501 Sez_0232 Streptococcus equi subsp. zooepidemicus MGCS10565 ABC transporter ATP-binding protein YP_002122623.1 256836 D 552526 CDS YP_002122624.1 195977380 6760556 257548..258897 1 NC_011134.1 similar to ref|NP_816713.1| hypothetical protein EF3103 [Enterococcus faecalis V583]; hypothetical protein 258897 6760556 Sez_0233 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002122624.1 257548 D 552526 CDS YP_002122625.1 195977381 6761447 259174..259539 1 NC_011134.1 similar to ref|NP_816711.1| hypothetical protein EF3101 [Enterococcus faecalis V583]; hypothetical protein 259539 6761447 Sez_0234 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002122625.1 259174 D 552526 CDS YP_002122626.1 195977382 6760555 259548..260039 1 NC_011134.1 similar to ref|NP_816709.1| transporter accessory protein, [Enterococcus faecalis V583]; transporter accessory protein 260039 6760555 Sez_0235 Streptococcus equi subsp. zooepidemicus MGCS10565 transporter accessory protein YP_002122626.1 259548 D 552526 CDS YP_002122627.1 195977383 6761373 260270..260629 1 NC_011134.1 protein component of RNaseP which catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'terminus; this enzyme also cleaves other RNA substrates; ribonuclease P 260629 rnpA 6761373 rnpA Streptococcus equi subsp. zooepidemicus MGCS10565 ribonuclease P YP_002122627.1 260270 D 552526 CDS YP_002122628.1 195977384 6760554 260613..261422 1 NC_011134.1 similar to ref|YP_001127782.1| membrane protein OxaA 1 precursor [Streptococcus pyogenes str. Manfredo]; Required for the insertion of integral membrane proteins into the membrane. May also be involved in protein secretion processes.; membrane protein OxaA 261422 oxaA1 6760554 oxaA1 Streptococcus equi subsp. zooepidemicus MGCS10565 membrane protein OxaA YP_002122628.1 260613 D 552526 CDS YP_002122629.1 195977385 6761441 261434..262333 1 NC_011134.1 similar to ref|YP_595942.1| jag protein [Streptococcus pyogenes MGAS9429]; RNA binding; Jag protein 262333 jag 6761441 jag Streptococcus equi subsp. zooepidemicus MGCS10565 Jag protein YP_002122629.1 261434 D 552526 CDS YP_002122630.1 195977386 6760553 262455..262688 1 NC_011134.1 similar to gb|EAY64209.1| conserved hypothetical protein [Burkholderia cenocepacia PC184]; hypothetical protein 262688 6760553 Sez_0239 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002122630.1 262455 D 552526 CDS YP_002122631.1 195977387 6761418 262860..263282 1 NC_011134.1 similar to ref|ZP_00230000.1| hypothetical protein LMOh7858_0095 [Listeria monocytogenes str. 4b H7858]; hypothetical protein 263282 6761418 Sez_0240 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002122631.1 262860 D 552526 CDS YP_002122632.1 195977388 6760552 263812..264522 1 NC_011134.1 Converts N-acetylmannosamine-6-phosphate to N-acetylglucosamine-6-phosphate; N-acetylmannosamine-6-phosphate 2-epimerase 264522 nanE 6760552 nanE Streptococcus equi subsp. zooepidemicus MGCS10565 N-acetylmannosamine-6-phosphate 2-epimerase YP_002122632.1 263812 D 552526 CDS YP_002122633.1 195977389 6761392 264527..266038 1 NC_011134.1 similar to ref|YP_001198767.1| Phosphotransferase system IIC component, glucose/maltose/N-acetylglucosamine-specific [Streptococcus suis 05ZYH33]; The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. This system is involved in glucose transport.; PTS system glucose-specific transporter subunit IICBA 266038 ptsG 6761392 ptsG Streptococcus equi subsp. zooepidemicus MGCS10565 PTS system glucose-specific transporter subunit IICBA YP_002122633.1 264527 D 552526 CDS YP_002122634.1 195977390 6760551 266040..266555 1 NC_011134.1 similar to ref|YP_603278.1| PTS system, glucose-specific IIABC component [Streptococcus pyogenes MGAS10750]; The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. This system is involved in glucose transport.; PTS system maltose and glucose-specific transporter subunit IIABC 266555 ptsG 6760551 ptsG Streptococcus equi subsp. zooepidemicus MGCS10565 PTS system maltose and glucose-specific transporter subunit IIABC YP_002122634.1 266040 D 552526 CDS YP_002122635.1 195977391 6761386 266959..267093 1 NC_011134.1 in Escherichia coli transcription of this gene is enhanced by polyamines; 50S ribosomal protein L34 267093 rpmH 6761386 rpmH Streptococcus equi subsp. zooepidemicus MGCS10565 50S ribosomal protein L34 YP_002122635.1 266959 D 552526 CDS YP_002122636.1 195977392 6760550 267380..268105 1 NC_011134.1 Converts N-acetylmannosamine-6-phosphate to N-acetylglucosamine-6-phosphate; N-acetylmannosamine-6-phosphate 2-epimerase 268105 nanE 6760550 nanE Streptococcus equi subsp. zooepidemicus MGCS10565 N-acetylmannosamine-6-phosphate 2-epimerase YP_002122636.1 267380 D 552526 CDS YP_002122637.1 195977393 6761364 268124..269437 1 NC_011134.1 similar to ref|YP_279676.1| N-acetylneuraminate-binding protein [Streptococcus pyogenes MGAS6180]; sugar ABC transporter substrate-binding protein 269437 6761364 Sez_0246 Streptococcus equi subsp. zooepidemicus MGCS10565 sugar ABC transporter substrate-binding protein YP_002122637.1 268124 D 552526 CDS YP_002122638.1 195977394 6760549 269559..270425 1 NC_011134.1 similar to ref|YP_597823.1| N-acetylneuraminate transport system permease [Streptococcus pyogenes MGAS10270]; Probably part of the binding-protein-dependent transport system yurMNO. Probably responsible for the translocation of the substrate across the membrane.; N-acetylneuraminate ABC transporter permease 270425 6760549 Sez_0247 Streptococcus equi subsp. zooepidemicus MGCS10565 N-acetylneuraminate ABC transporter permease YP_002122638.1 269559 D 552526 CDS YP_002122639.1 195977395 6760872 270438..271268 1 NC_011134.1 similar to ref|NP_663987.1| sugar transport protein (permease) [Streptococcus pyogenes MGAS315]; Part of the binding-protein-dependent transport system for L-arabinose. Probably responsible for the translocation of the substrate across the membrane.; sugar ABC transporter permease 271268 6760872 Sez_0248 Streptococcus equi subsp. zooepidemicus MGCS10565 sugar ABC transporter permease YP_002122639.1 270438 D 552526 CDS YP_002122640.1 195977396 6760548 271295..271750 1 NC_011134.1 similar to ref|NP_606523.1| hypothetical protein spyM18_0238 [Streptococcus pyogenes MGAS8232]; hypothetical protein 271750 6760548 Sez_0249 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002122640.1 271295 D 552526 CDS YP_002122641.1 195977397 6760870 271775..272425 1 NC_011134.1 similar to ref|YP_595949.1| hypothetical membrane spanning protein [Streptococcus pyogenes MGAS9429]; hypothetical protein 272425 6760870 Sez_0250 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002122641.1 271775 D 552526 CDS YP_002122642.1 195977398 6760547 272454..273374 1 NC_011134.1 similar to ref|NP_268611.1| acylneuraminate lyase [Streptococcus pyogenes M1 GAS]; Catalyzes the cleavage of N-acetylneuraminic acid (sialic acid) to form pyruvate and N-acetylmannosamine via a Schiff base intermediate.; N-acetylneuraminate lyase 273374 nanA 6760547 nanA Streptococcus equi subsp. zooepidemicus MGCS10565 N-acetylneuraminate lyase YP_002122642.1 272454 D 552526 CDS YP_002122643.1 195977399 6760868 273389..274273 1 NC_011134.1 Catalysis of ATP + N-acyl-D-mannosamine = ADP + N-acyl-D-mannosamine 6-phosphate.; N-acetylmannosamine kinase 274273 6760868 Sez_0252 Streptococcus equi subsp. zooepidemicus MGCS10565 N-acetylmannosamine kinase YP_002122643.1 273389 D 552526 CDS YP_002122644.1 195977400 6760545 274273..275241 1 NC_011134.1 cephalosporin-C deacetylase; similar to ref|YP_328767.1| acetyl xylan esterase, [Streptococcus agalactiae A909]; acetyl xylan esterase 1 275241 6760545 Sez_0253 Streptococcus equi subsp. zooepidemicus MGCS10565 acetyl xylan esterase 1 YP_002122644.1 274273 D 552526 CDS YP_002122645.1 195977401 6760866 complement(275390..276184) 1 NC_011134.1 similar to ref|YP_328768.1| phosphosugar-binding transcriptional regulator, RpiR family [Streptococcus agalactiae A909]; Binding to a specific DNA sequence in order to modulate transcription.; sialic acid utilization regulator, RpiR family 276184 rpiR 6760866 rpiR Streptococcus equi subsp. zooepidemicus MGCS10565 sialic acid utilization regulator, RpiR family YP_002122645.1 275390 R 552526 CDS YP_002122646.1 195977402 6760544 276443..277216 1 NC_011134.1 similar to ref|YP_001127793.1| TatD related DNase [Streptococcus pyogenes str. Manfredo]; deoxyribonuclease 277216 6760544 Sez_0255 Streptococcus equi subsp. zooepidemicus MGCS10565 deoxyribonuclease YP_002122646.1 276443 D 552526 CDS YP_002122647.1 195977403 6760864 277188..277784 1 NC_011134.1 similar to ref|YP_279684.1| ribonuclease M5 [Streptococcus pyogenes MGAS6180]; Interacting selectively with any nucleic acid.; ribonuclease M5 277784 6760864 Sez_0256 Streptococcus equi subsp. zooepidemicus MGCS10565 ribonuclease M5 YP_002122647.1 277188 D 552526 CDS YP_002122648.1 195977404 6760543 complement(277855..278529) 1 NC_011134.1 similar to ref|YP_001201713.1| Thiol-disulfide isomerase and thioredoxin [Streptococcus suis 98HAH33]; transport accessory protein 278529 6760543 Sez_0257 Streptococcus equi subsp. zooepidemicus MGCS10565 transport accessory protein YP_002122648.1 277855 R 552526 CDS YP_002122649.1 195977405 6760862 279168..280040 1 NC_011134.1 catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin; dimethyladenosine transferase 280040 ksgA 6760862 ksgA Streptococcus equi subsp. zooepidemicus MGCS10565 dimethyladenosine transferase YP_002122649.1 279168 D 552526 CDS YP_002122650.1 195977406 6760542 280201..281073 1 NC_011134.1 EngC; RsgA; CpgA; circularly permuted GTPase; ribosome small subunit-dependent GTPase A; has the pattern G4-G1-G3 as opposed to other GTPases; interacts strongly with 30S ribosome which stimulates GTPase activity; ribosome-associated GTPase 281073 engC 6760542 engC Streptococcus equi subsp. zooepidemicus MGCS10565 ribosome-associated GTPase YP_002122650.1 280201 D 552526 CDS YP_002122651.1 195977407 6760857 281082..281744 1 NC_011134.1 catalyzes the interconversion of D-ribulose 5-phosphate to xylulose 5-phosphate; ribulose-phosphate 3-epimerase 281744 cbbE 6760857 cbbE Streptococcus equi subsp. zooepidemicus MGCS10565 ribulose-phosphate 3-epimerase YP_002122651.1 281082 D 552526 CDS YP_002122652.1 195977408 6760541 281737..282369 1 NC_011134.1 similar to ref|YP_601714.1| Thiamin pyrophosphokinase [Streptococcus pyogenes MGAS10750]; Catalyzes the phosphorylation of thiamine to thiamine pyrophosphate.; thiamine pyrophosphokinase 282369 thiN 6760541 thiN Streptococcus equi subsp. zooepidemicus MGCS10565 thiamine pyrophosphokinase YP_002122652.1 281737 D 552526 CDS YP_002122653.1 195977409 6760855 282389..283642 1 NC_011134.1 similar to ref|YP_601715.1| RmuC family protein [Streptococcus pyogenes MGAS10750]; Involved in DNA recombination.; DNA recombination protein RmuC-like 283642 rmuC 6760855 rmuC Streptococcus equi subsp. zooepidemicus MGCS10565 DNA recombination protein RmuC-like YP_002122653.1 282389 D 552526 CDS YP_002122654.1 195977410 6760540 283632..284570 1 NC_011134.1 similar to ref|NP_268621.1| CMP-binding factor [Streptococcus pyogenes M1 GAS]; 3'-5' exoribonuclease; CMP-binding factor 284570 6760540 Sez_0263 Streptococcus equi subsp. zooepidemicus MGCS10565 CMP-binding factor YP_002122654.1 283632 D 552526 CDS YP_002122655.1 195977411 6760853 284694..285485 1 NC_011134.1 similar to ref|NP_268622.1| purine operon repressor [Streptococcus pyogenes M1 GAS]; Controls the transcription of the pur operon for purine biosynthetic genes.; pur operon repressor 285485 purR 6760853 purR Streptococcus equi subsp. zooepidemicus MGCS10565 pur operon repressor YP_002122655.1 284694 D 552526 CDS YP_002122656.1 195977412 6760539 285522..288026 1 NC_011134.1 similar to ref|NP_268623.1| surface exclusion protein [Streptococcus pyogenes M1 GAS]; surface exclusion protein 288026 6760539 Sez_0265 Streptococcus equi subsp. zooepidemicus MGCS10565 surface exclusion protein YP_002122656.1 285522 D 552526 CDS YP_002122657.1 195977413 6760850 288208..288621 1 NC_011134.1 interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance; 30S ribosomal protein S12 288621 rpsL 6760850 rpsL Streptococcus equi subsp. zooepidemicus MGCS10565 30S ribosomal protein S12 YP_002122657.1 288208 D 552526 CDS YP_002122658.1 195977414 6760537 288642..289112 1 NC_011134.1 binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit; 30S ribosomal protein S7 289112 rpsG 6760537 rpsG Streptococcus equi subsp. zooepidemicus MGCS10565 30S ribosomal protein S7 YP_002122658.1 288642 D 552526 CDS YP_002122659.1 195977415 6760846 289441..291519 1 NC_011134.1 EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene; elongation factor G 291519 fus 6760846 fus Streptococcus equi subsp. zooepidemicus MGCS10565 elongation factor G YP_002122659.1 289441 D 552526 CDS YP_002122660.1 195977416 6760536 complement(291651..291821) 1 NC_011134.1 hypothetical protein 291821 6760536 Sez_0269 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002122660.1 291651 R 552526 CDS YP_002122661.1 195977417 6760844 291899..292909 1 NC_011134.1 similar to dbj|BAD37145.1| glyceraldehyde-3-phosphate dehydrogenase [Streptococcus gordonii]; Also binds human plasminogen, Nephritis associated plasmin receptor, moonlighting dual function non-classical secreted protein.; NAD-dependent glyceraldehyde-3-phosphate dehydrogenase / plasmin(ogen) receptor 292909 6760844 Sez_0270 Streptococcus equi subsp. zooepidemicus MGCS10565 NAD-dependent glyceraldehyde-3-phosphate dehydrogenase / plasmin(ogen) receptor YP_002122661.1 291899 D 552526 CDS YP_002122662.1 195977418 6760535 293453..294307 1 NC_011134.1 similar to emb|CAA73175.1| acid phosphatase [Streptococcus dysgalactiae subsp. equisimilis]; lipoprotein E 294307 6760535 Sez_0271 Streptococcus equi subsp. zooepidemicus MGCS10565 lipoprotein E YP_002122662.1 293453 D 552526 CDS YP_002122663.1 195977419 6760841 294516..295712 1 NC_011134.1 Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway; phosphoglycerate kinase 295712 pgk 6760841 pgk Streptococcus equi subsp. zooepidemicus MGCS10565 phosphoglycerate kinase YP_002122663.1 294516 D 552526 CDS YP_002122664.1 195977420 6760534 295902..296030 1 NC_011134.1 hypothetical protein 296030 6760534 Sez_0273 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002122664.1 295902 D 552526 CDS YP_002122665.1 195977421 6760839 complement(296183..296317) 1 NC_011134.1 hypothetical protein 296317 6760839 Sez_0274 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002122665.1 296183 R 552526 CDS YP_002122666.1 195977422 6760532 296280..296657 1 NC_011134.1 similar to ref|YP_597334.1| hypothetical protein MGAS9429_Spy1603 [Streptococcus pyogenes MGAS9429]; hypothetical protein 296657 6760532 Sez_0275 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002122666.1 296280 D 552526 CDS YP_002122667.1 195977423 6760531 297142..298488 1 NC_011134.1 similar to ref|YP_597332.1| glutamine synthetase [Streptococcus pyogenes MGAS9429]; Plays an essential role in the metabolism of nitrogen by catalyzing the condensation of glutamate and ammonia to form glutamine, Class I enzymes (GSI) are specific to prokaryotes, and are oligomers of 12 identical subunits. The activity of GSI-type enzyme is controlled by the adenylation of a tyrosine residue. The adenylated enzyme is inactive.; glutamine synthetase 298488 glnA 6760531 glnA Streptococcus equi subsp. zooepidemicus MGCS10565 glutamine synthetase YP_002122667.1 297142 D 552526 CDS YP_002122668.1 195977424 6760833 298721..300379 1 NC_011134.1 similar to ref|NP_687990.1| ABC transporter, substrate-binding protein [Streptococcus agalactiae 2603V/R]; This protein is a component of the oligopeptide permease, a binding protein-dependent transport system, It binds peptides up to five amino acids long with high affinity. Also required for sporulation and competence.; oligopeptide-binding protein OppA precursor 300379 oppA 6760833 oppA Streptococcus equi subsp. zooepidemicus MGCS10565 oligopeptide-binding protein OppA precursor YP_002122668.1 298721 D 552526 CDS YP_002122669.1 195977425 6760530 300546..301460 1 NC_011134.1 similar to ref|NP_687185.1| oligopeptide ABC transporter, permease [Streptococcus agalactiae 2603V/R]; Part of the binding-protein-dependent transport system for oligopeptides; probably responsible for the translocation of the substrate across the membrane. Also required for sporulation and competence.; oligopeptide transport system permease OppB 301460 oppB 6760530 oppB Streptococcus equi subsp. zooepidemicus MGCS10565 oligopeptide transport system permease OppB YP_002122669.1 300546 D 552526 CDS YP_002122670.1 195977426 6760831 301470..302501 1 NC_011134.1 similar to ref|NP_687186.1| oligopeptide ABC transporter, permease [Streptococcus agalactiae 2603V/R]; Part of the binding-protein-dependent transport system for oligopeptides; probably responsible for the translocation of the substrate across the membrane. Also required for sporulation and competence.; oligopeptide transport system permease OppC 302501 oppC 6760831 oppC Streptococcus equi subsp. zooepidemicus MGCS10565 oligopeptide transport system permease OppC YP_002122670.1 301470 D 552526 CDS YP_002122671.1 195977427 6760529 302514..303560 1 NC_011134.1 similar to ref|NP_687187.1| oligopeptide ABC transporter, ATP-binding protein [Streptococcus agalactiae 2603V/R]; Part of the binding protein-dependent transport system for oligopeptides. Probably responsible for energy coupling to the transport system. Required for sporulation and competence.; oligopeptide transport ATP-binding protein OppD 303560 oppD 6760529 oppD Streptococcus equi subsp. zooepidemicus MGCS10565 oligopeptide transport ATP-binding protein OppD YP_002122671.1 302514 D 552526 CDS YP_002122672.1 195977428 6760829 303560..304495 1 NC_011134.1 similar to ref|NP_687188.1| oligopeptide ABC transporter, ATP-binding protein [Streptococcus agalactiae 2603V/R]; Part of the binding-protein-dependent transport system for oligopeptides. Probably responsible for energy coupling to the transport system.; oligopeptide transport ATP-binding protein OppF 304495 oppF 6760829 oppF Streptococcus equi subsp. zooepidemicus MGCS10565 oligopeptide transport ATP-binding protein OppF YP_002122672.1 303560 D 552526 CDS YP_002122673.1 195977429 6760528 complement(305117..306799) 1 NC_011134.1 similar to ref|ZP_00366343.1| COG0595: Predicted hydrolase of the metallo-beta-lactamase superfamily [Streptococcus pyogenes M49 591]; metallo-beta-lactamase family protein, Zn-dependent hydrolase 306799 ykqC 6760528 ykqC Streptococcus equi subsp. zooepidemicus MGCS10565 metallo-beta-lactamase family protein, Zn-dependent hydrolase YP_002122673.1 305117 R 552526 CDS YP_002122674.1 195977430 6760827 complement(306801..307031) 1 NC_011134.1 similar to ref|YP_603146.1| transcriptional regulator [Streptococcus pyogenes MGAS10750]; hypothetical protein 307031 6760827 Sez_0285 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002122674.1 306801 R 552526 CDS YP_002122675.1 195977431 6760527 307317..308015 1 NC_011134.1 similar to ref|YP_603145.1| Non-proteolytic protein, peptidase family M22 [Streptococcus pyogenes MGAS10750]; molecular chaperone metal-dependent protease-like 308015 6760527 Sez_0286 Streptococcus equi subsp. zooepidemicus MGCS10565 molecular chaperone metal-dependent protease-like YP_002122675.1 307317 D 552526 CDS YP_002122676.1 195977432 6760824 308018..308443 1 NC_011134.1 similar to ref|YP_597328.1| ribosomal-protein-S18-alanine acetyltransferase [Streptococcus pyogenes MGAS9429]; This Enzyme Acetylates The N-Terminal Alanine Of Ribosomal Protein S18.; ribosomal-protein-alanine acetyltransferase 308443 rimI 6760824 rimI Streptococcus equi subsp. zooepidemicus MGCS10565 ribosomal-protein-alanine acetyltransferase YP_002122676.1 308018 D 552526 CDS YP_002122677.1 195977433 6760526 308433..309449 1 NC_011134.1 in most organisms, only the N-terminal domain is present in a single polypeptide; in some archaea this domain is fused to a kinase domain; this gene is essential for growth in Escherichia coli and Bacillus subtilis; the secreted glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins; the Pyrococcus structure shows DNA-binding properties, iron-binding, ATP-binding, and AP endonuclease activity; DNA-binding/iron metalloprotein/AP endonuclease 309449 6760526 Sez_0288 Streptococcus equi subsp. zooepidemicus MGCS10565 DNA-binding/iron metalloprotein/AP endonuclease YP_002122677.1 308433 D 552526 CDS YP_002122678.1 195977434 6760821 309471..310499 1 NC_011134.1 similar to ref|ZP_00875785.1| Protein of unknown function DUF218 [Streptococcus suis 89/1591]; hypothetical protein 310499 6760821 Sez_0289 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002122678.1 309471 D 552526 CDS YP_002122679.1 195977435 6760525 complement(310897..311232) 1 NC_011134.1 similar to ref|ZP_00366338.1| COG0199: Ribosomal protein S14 [Streptococcus pyogenes M49 591]; Known to be required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.; 30S ribosomal protein S14 311232 rpsN2 6760525 rpsN2 Streptococcus equi subsp. zooepidemicus MGCS10565 30S ribosomal protein S14 YP_002122679.1 310897 R 552526 CDS YP_002122680.1 195977436 6760818 complement(311360..312532) 1 NC_011134.1 similar to ref|YP_281042.1| NAD(FAD)-utilizing dehydrogenase [Streptococcus pyogenes MGAS6180]; NAD(FAD)-utilizing dehydrogenase 312532 6760818 Sez_0291 Streptococcus equi subsp. zooepidemicus MGCS10565 NAD(FAD)-utilizing dehydrogenase YP_002122680.1 311360 R 552526 CDS YP_002122681.1 195977437 6760524 312658..313188 1 NC_011134.1 similar to ref|YP_001127858.1| DNA-binding protein [Streptococcus pyogenes str. Manfredo]; hypothetical protein 313188 6760524 Sez_0292 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002122681.1 312658 D 552526 CDS YP_002122682.1 195977438 6760814 313233..313820 1 NC_011134.1 3'-5' exonuclease of DNA polymerase III; DNA polymerase III subunit epsilon 313820 polC 6760814 polC Streptococcus equi subsp. zooepidemicus MGCS10565 DNA polymerase III subunit epsilon YP_002122682.1 313233 D 552526 CDS YP_002122683.1 195977439 6760522 313915..314646 1 NC_011134.1 similar to ref|YP_599257.1| MerR family transcriptional regulator [Streptococcus pyogenes MGAS10270]; Transcriptional regulator.; MerR family transcriptional regulator 314646 6760522 Sez_0294 Streptococcus equi subsp. zooepidemicus MGCS10565 MerR family transcriptional regulator YP_002122683.1 313915 D 552526 CDS YP_002122684.1 195977440 6760812 314722..315237 1 NC_011134.1 similar to ref|YP_602677.1| Transposase [Streptococcus pyogenes MGAS10750]; transposase IS861 orfA 315237 6760812 Sez_0295 Streptococcus equi subsp. zooepidemicus MGCS10565 transposase IS861 orfA YP_002122684.1 314722 D 552526 CDS YP_002122685.1 195977441 6760521 315261..316064 1 NC_011134.1 similar to ref|YP_596865.1| transposase [Streptococcus pyogenes MGAS9429]; transposase IS861 orfB 316064 6760521 Sez_0296 Streptococcus equi subsp. zooepidemicus MGCS10565 transposase IS861 orfB YP_002122685.1 315261 D 552526 CDS YP_002122686.1 195977442 6760810 complement(316121..316420) 1 NC_011134.1 similar to ref|YP_281033.1| hypothetical protein M28_Spy1568 [Streptococcus pyogenes MGAS6180]; hypothetical protein 316420 6760810 Sez_0297 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002122686.1 316121 R 552526 CDS YP_002122687.1 195977443 6760520 complement(316498..317649) 1 NC_011134.1 similar to ref|NP_816189.1| site-specific recombinase, phage integrase family [Enterococcus faecalis V583]; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The xerC-xerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.; tyrosine recombinase XerC 317649 intR 6760520 intR Streptococcus equi subsp. zooepidemicus MGCS10565 tyrosine recombinase XerC YP_002122687.1 316498 R 552526 CDS YP_002122688.1 195977444 6760806 complement(317636..317923) 1 NC_011134.1 similar to ref|NP_813967.1| hypothetical protein EF0165 [Enterococcus faecalis V583]; hypothetical protein 317923 6760806 Sez_0299 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002122688.1 317636 R 552526 CDS YP_002122689.1 195977445 6760519 complement(317975..319210) 1 NC_011134.1 similar to ref|NP_965557.1| hypothetical protein LJ1751 [Lactobacillus johnsonii NCC 533]; Unknown, has some similarity with plasmid/phage replication initiation proteins may function with Sez_0298 which has similarity with plasmid/phage integrase/recombinase.; hypothetical protein 319210 6760519 Sez_0300 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002122689.1 317975 R 552526 CDS YP_002122690.1 195977446 6760803 complement(319372..319665) 1 NC_011134.1 similar to ref|ZP_01817519.1| hypothetical protein CGSSp3BS71_03347 [Streptococcus pneumoniae SP3-BS71]; hypothetical protein 319665 6760803 Sez_0301 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002122690.1 319372 R 552526 CDS YP_002122691.1 195977447 6760518 complement(320151..320594) 1 NC_011134.1 similar to ref|XP_788744.2| PREDICTED: similar to kelch-like ECH-associated protein 1 [Strongylocentrotus purpuratus]; hypothetical protein 320594 6760518 Sez_0302 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002122691.1 320151 R 552526 CDS YP_002122692.1 195977448 6760801 320885..322174 1 NC_011134.1 similar to ref|ZP_01968479.1| hypothetical protein RUMTOR_02056 [Ruminococcus torques ATCC 27756]; hypothetical protein 322174 6760801 Sez_0303 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002122692.1 320885 D 552526 CDS YP_002122693.1 195977449 6760517 complement(322293..323123) 1 NC_011134.1 similar to ref|XP_001431093.1| hypothetical protein GSPATT00033548001 [Paramecium tetraurelia strain d4-2]; hypothetical protein 323123 6760517 Sez_0304 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002122693.1 322293 R 552526 CDS YP_002122694.1 195977450 6760799 323629..323766 1 NC_011134.1 similar to ref|YP_536282.1| hypothetical protein LSL_1395 [Lactobacillus salivarius UCC118]; hypothetical protein 323766 6760799 Sez_0305 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002122694.1 323629 D 552526 CDS YP_002122695.1 195977451 6760516 323797..324507 1 NC_011134.1 similar to ref|XP_001592791.1| hypothetical protein SS1G_05712 [Sclerotinia sclerotiorum 1980]; hypothetical protein 324507 6760516 Sez_0306 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002122695.1 323797 D 552526 CDS YP_002122696.1 195977452 6760797 324534..325703 1 NC_011134.1 similar to ref|ZP_00875721.1| Helix-turn-helix motif:Protein of unknown function DUF955 [Streptococcus suis 89/1591]; transcriptional regulator 325703 6760797 Sez_0307 Streptococcus equi subsp. zooepidemicus MGCS10565 transcriptional regulator YP_002122696.1 324534 D 552526 CDS YP_002122697.1 195977453 6760515 325743..326762 1 NC_011134.1 similar to ref|YP_001308760.1| hypothetical protein Cbei_1630 [Clostridium beijerinckii NCIMB 8052]; hypothetical protein 326762 6760515 Sez_0308 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002122697.1 325743 D 552526 CDS YP_002122698.1 195977454 6760795 327184..327321 1 NC_011134.1 hypothetical protein 327321 6760795 Sez_0309 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002122698.1 327184 D 552526 CDS YP_002122699.1 195977455 6760514 327391..327834 1 NC_011134.1 similar to ref|YP_330353.1| hypothetical protein SAK_1753 [Streptococcus agalactiae A909]; hypothetical protein 327834 6760514 Sez_0310 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002122699.1 327391 D 552526 CDS YP_002122700.1 195977456 6760793 327973..328659 1 NC_011134.1 similar to ref|NP_734897.1| similar to two-component response regulator [Streptococcus agalactiae NEM316]; Member of the two-component regulatory system, has some similarity with SaeR and PhoP.; DNA-binding response regulator 328659 6760793 Sez_0311 Streptococcus equi subsp. zooepidemicus MGCS10565 DNA-binding response regulator YP_002122700.1 327973 D 552526 CDS YP_002122701.1 195977457 6760513 328697..329707 1 NC_011134.1 similar to ref|NP_687428.1| sensor histidine kinase [Streptococcus agalactiae 2603V/R]; Member of the two-component regulatory system, has similarity with SaeS and PhoR.; two component system histidine kinase 329707 6760513 Sez_0312 Streptococcus equi subsp. zooepidemicus MGCS10565 two component system histidine kinase YP_002122701.1 328697 D 552526 CDS YP_002122702.1 195977458 6760790 complement(330079..331809) 1 NC_011134.1 similar to dbj|BAD00710.1| fibronectin-binding protein [Streptococcus equi subsp. zooepidemicus]; Unknown, cell surface fibronectin-binding protein.; fibronectin-binding protein Fnz 331809 fnz 6760790 fnz Streptococcus equi subsp. zooepidemicus MGCS10565 fibronectin-binding protein Fnz YP_002122702.1 330079 R 552526 CDS YP_002122703.1 195977459 6760511 332050..333558 1 NC_011134.1 similar to ref|NP_268584.1| regulatory protein - RofA related [Streptococcus pyogenes M1 GAS]; RofA-like, regulator of adjacent predicted cell surface fibronectin-binding protein.; transcriptional regulator, RofA-like protein (RALP) 333558 6760511 Sez_0314 Streptococcus equi subsp. zooepidemicus MGCS10565 transcriptional regulator, RofA-like protein (RALP) YP_002122703.1 332050 D 552526 CDS YP_002122704.1 195977460 6760788 334154..334936 1 NC_011134.1 similar to ref|YP_001643140.1| Abortive infection protein [Bacillus weihenstephanensis KBAB4]; CAAX amino terminal protease family protein 334936 6760788 Sez_0315 Streptococcus equi subsp. zooepidemicus MGCS10565 CAAX amino terminal protease family protein YP_002122704.1 334154 D 552526 CDS YP_002122705.1 195977461 6760510 complement(335194..335508) 1 NC_011134.1 similar to ref|NP_269854.1| repressor - phage associated [Streptococcus pyogenes M1 GAS]; repressor 335508 6760510 Sez_0316 Streptococcus equi subsp. zooepidemicus MGCS10565 repressor YP_002122705.1 335194 R 552526 CDS YP_002122706.1 195977462 6760786 335726..335968 1 NC_011134.1 similar to ref|YP_060907.1| Transcriptional regulator, Cro/CI family [Streptococcus pyogenes MGAS10394]; Cro/CI family transcriptional regulator 335968 6760786 Sez_0317 Streptococcus equi subsp. zooepidemicus MGCS10565 Cro/CI family transcriptional regulator YP_002122706.1 335726 D 552526 CDS YP_002122707.1 195977463 6760509 336157..336549 1 NC_011134.1 similar to ref|YP_329140.1| pyridoxamine 5'-phosphate oxidase family [Streptococcus agalactiae A909]; hypothetical protein 336549 6760509 Sez_0318 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002122707.1 336157 D 552526 CDS YP_002122708.1 195977464 6760783 complement(336655..338940) 1 NC_011134.1 catalyzes the removal of N-terminal dipeptides when proline is the penultimate residue; x-prolyl-dipeptidyl aminopeptidase 338940 pepX 6760783 pepX Streptococcus equi subsp. zooepidemicus MGCS10565 x-prolyl-dipeptidyl aminopeptidase YP_002122708.1 336655 R 552526 CDS YP_002122709.1 195977465 6760508 complement(338960..339619) 1 NC_011134.1 similar to ref|NP_269852.1| transcriptional regulatory protein [Streptococcus pyogenes M1 GAS]; Crp/Fnr family transcriptional regulator 339619 6760508 Sez_0320 Streptococcus equi subsp. zooepidemicus MGCS10565 Crp/Fnr family transcriptional regulator YP_002122709.1 338960 R 552526 CDS YP_002122710.1 195977466 6760781 339788..340987 1 NC_011134.1 similar to ref|YP_281028.1| quinolone resistance norA protein [Streptococcus pyogenes MGAS6180]; quinolone antibiotic resistance protein.; major facilitator superfamily transporter 340987 norA 6760781 norA Streptococcus equi subsp. zooepidemicus MGCS10565 major facilitator superfamily transporter YP_002122710.1 339788 D 552526 CDS YP_002122711.1 195977467 6760507 341007..341459 1 NC_011134.1 similar to ref|NP_688723.1| universal stress protein family [Streptococcus agalactiae 2603V/R]; universal stress protein family 341459 6760507 Sez_0322 Streptococcus equi subsp. zooepidemicus MGCS10565 universal stress protein family YP_002122711.1 341007 D 552526 CDS YP_002122712.1 195977468 6760777 341579..342409 1 NC_011134.1 similar to ref|YP_601194.1| Aquaporin / Glycerol uptake facilitator protein [Streptococcus pyogenes MGAS2096]; Mixed channel protein that transports both water and glycerol.; glycerol facilitator-aquaporin Gla 342409 gla 6760777 gla Streptococcus equi subsp. zooepidemicus MGCS10565 glycerol facilitator-aquaporin Gla YP_002122712.1 341579 D 552526 CDS YP_002122713.1 195977469 6760506 342901..343656 1 NC_011134.1 similar to ref|NP_269848.1| C3-degrading proteinase [Streptococcus pyogenes M1 GAS]; C3-degrading proteinase 343656 6760506 Sez_0324 Streptococcus equi subsp. zooepidemicus MGCS10565 C3-degrading proteinase YP_002122713.1 342901 D 552526 CDS YP_002122714.1 195977470 6760775 343653..344603 1 NC_011134.1 similar to gb|AAT87717.1| Penicillin-binding protein [Streptococcus pyogenes MGAS10394]; Unknown, similar to beta lactamase.; esterase 344603 6760775 Sez_0325 Streptococcus equi subsp. zooepidemicus MGCS10565 esterase YP_002122714.1 343653 D 552526 CDS YP_002122715.1 195977471 6760505 complement(344824..347211) 1 NC_011134.1 similar to ref|NP_358009.1| Pyruvate formate-lyase [Streptococcus pneumoniae R6]; Glucose metabolism (nonoxidative conversion).; pyruvate formate-lyase 347211 pfl 6760505 pfl Streptococcus equi subsp. zooepidemicus MGCS10565 pyruvate formate-lyase YP_002122715.1 344824 R 552526 CDS YP_002122716.1 195977472 6760773 347357..348460 1 NC_011134.1 involved in translesion DNA polymerization with beta clamp of polymerase III; belongs to Y family of polymerases; does not contain proofreading function; DNA polymerase IV 348460 dinB 6760773 dinB Streptococcus equi subsp. zooepidemicus MGCS10565 DNA polymerase IV YP_002122716.1 347357 D 552526 CDS YP_002122717.1 195977473 6760504 complement(348603..349088) 1 NC_011134.1 similar to ref|NP_665398.1| hypothetical protein SpyM3_1594 [Streptococcus pyogenes MGAS315]; hypothetical protein 349088 6760504 Sez_0328 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002122717.1 348603 R 552526 CDS YP_002122718.1 195977474 6760771 complement(349184..351688) 1 NC_011134.1 similar to ref|YP_603119.1| Exodeoxyribonuclease V alpha chain [Streptococcus pyogenes MGAS10750]; Exhibits several catalytic activities, including ATP-dependent exonuclease, ATP-stimulated endonuclease, ATP-dependent unwinding and DNA-dependent ATPase activities. strand cleavage occurs 5' to 3' during the unwinding of duplex DNA at Chi sequences, which locally stimulate recombination.; exodeoxyribonuclease V subunit alpha 351688 recD 6760771 recD Streptococcus equi subsp. zooepidemicus MGCS10565 exodeoxyribonuclease V subunit alpha YP_002122718.1 349184 R 552526 CDS YP_002122719.1 195977475 6760503 complement(351812..352411) 1 NC_011134.1 similar to ref|YP_603118.1| Signal peptidase I [Streptococcus pyogenes MGAS10750]; signal peptidase I 352411 lepB 6760503 lepB Streptococcus equi subsp. zooepidemicus MGCS10565 signal peptidase I YP_002122719.1 351812 R 552526 CDS YP_002122720.1 195977476 6760769 complement(352436..353311) 1 NC_011134.1 An endonuclease that specifically degrades the RNA strand of RNA-DNA hybrids; ribonuclease HIII 353311 rnhC 6760769 rnhC Streptococcus equi subsp. zooepidemicus MGCS10565 ribonuclease HIII YP_002122720.1 352436 R 552526 CDS YP_002122721.1 195977477 6760502 353462..353773 1 NC_011134.1 similar to ref|YP_597299.1| hypothetical cytosolic protein [Streptococcus pyogenes MGAS9429]; hypothetical protein 353773 6760502 Sez_0332 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002122721.1 353462 D 552526 CDS YP_002122722.1 195977478 6760767 353770..354318 1 NC_011134.1 similar to ref|YP_597298.1| CvpA family membrane protein [Streptococcus pyogenes MGAS9429]; colicin V production protein CvpA 354318 cvpA 6760767 cvpA Streptococcus equi subsp. zooepidemicus MGCS10565 colicin V production protein CvpA YP_002122722.1 353770 D 552526 CDS YP_002122723.1 195977479 6760501 354391..356727 1 NC_011134.1 similar to ref|YP_140176.1| DNA mismatch repair protein [Streptococcus thermophilus LMG 18311]; recombination inhibitory protein MutS2 356727 mutSB 6760501 mutSB Streptococcus equi subsp. zooepidemicus MGCS10565 recombination inhibitory protein MutS2 YP_002122723.1 354391 D 552526 CDS YP_002122724.1 195977480 6760765 356864..357073 1 NC_011134.1 hypothetical protein 357073 6760765 Sez_0335 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002122724.1 356864 D 552526 CDS YP_002122725.1 195977481 6760500 complement(357070..358422) 1 NC_011134.1 Involved in disulfide oxidoreductase activity and electron transport; pyridine nucleotide-disulfide oxidoreductase 358422 ykgC 6760500 ykgC Streptococcus equi subsp. zooepidemicus MGCS10565 pyridine nucleotide-disulfide oxidoreductase YP_002122725.1 357070 R 552526 CDS YP_002122726.1 195977482 6760763 358568..358882 1 NC_011134.1 similar to ref|NP_722180.1| thioredoxin [Streptococcus mutans UA159]; Component of the thioredoxin-thioredoxin reductase system. Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions.; thioredoxin 358882 trxA 6760763 trxA Streptococcus equi subsp. zooepidemicus MGCS10565 thioredoxin YP_002122726.1 358568 D 552526 CDS YP_002122727.1 195977483 6760499 complement(359128..360108) 1 NC_011134.1 similar to gb|AAQ08496.1| Szp protein [Streptococcus equi subsp. zooepidemicus]; This protein is one of the different antigenic serotypes of protein M. Protein M is closely associated with virulence of the bacterium and can render the organism resistant to phagocytosis.; M-like protein 360108 mlpZ 6760499 mlpZ Streptococcus equi subsp. zooepidemicus MGCS10565 M-like protein YP_002122727.1 359128 R 552526 CDS YP_002122728.1 195977484 6760761 complement(360903..362051) 1 NC_011134.1 similar to ref|YP_140171.1| A/G-specific adenine glycosylase [Streptococcus thermophilus LMG 18311]; Adenine glycosylase active on G-A and C-A mispairs.; A/G-specific adenine glycosylase 362051 mutY 6760761 mutY Streptococcus equi subsp. zooepidemicus MGCS10565 A/G-specific adenine glycosylase YP_002122728.1 360903 R 552526 CDS YP_002122729.1 195977485 6760498 362177..362365 1 NC_011134.1 similar to ref|NP_721760.1| hypothetical protein SMU.1400c [Streptococcus mutans UA159]; hypothetical protein 362365 6760498 Sez_0340 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002122729.1 362177 D 552526 CDS YP_002122730.1 195977486 6760759 363170..363310 1 NC_011134.1 hypothetical protein 363310 6760759 Sez_0341 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002122730.1 363170 D 552526 CDS YP_002122731.1 195977487 6760497 363429..363719 1 NC_011134.1 binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21; 30S ribosomal protein S6 363719 rpsF 6760497 rpsF Streptococcus equi subsp. zooepidemicus MGCS10565 30S ribosomal protein S6 YP_002122731.1 363429 D 552526 CDS YP_002122732.1 195977488 6760756 363738..364226 1 NC_011134.1 binds to single stranded DNA and may facilitate the binding and interaction of other proteins to DNA; single-stranded DNA-binding protein 364226 ssb2 6760756 ssb2 Streptococcus equi subsp. zooepidemicus MGCS10565 single-stranded DNA-binding protein YP_002122732.1 363738 D 552526 CDS YP_002122733.1 195977489 6760496 364385..364624 1 NC_011134.1 binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit; 30S ribosomal protein S18 364624 rpsR 6760496 rpsR Streptococcus equi subsp. zooepidemicus MGCS10565 30S ribosomal protein S18 YP_002122733.1 364385 D 552526 CDS YP_002122734.1 195977490 6760754 364825..365340 1 NC_011134.1 similar to ref|YP_602677.1| Transposase [Streptococcus pyogenes MGAS10750]; transposase IS861 orfA 365340 6760754 Sez_0345 Streptococcus equi subsp. zooepidemicus MGCS10565 transposase IS861 orfA YP_002122734.1 364825 D 552526 CDS YP_002122735.1 195977491 6760495 365364..366167 1 NC_011134.1 similar to ref|YP_596865.1| transposase [Streptococcus pyogenes MGAS9429]; transposase IS861 orfB 366167 6760495 Sez_0346 Streptococcus equi subsp. zooepidemicus MGCS10565 transposase IS861 orfB YP_002122735.1 365364 D 552526 CDS YP_002122736.1 195977492 6760752 complement(366317..366967) 1 NC_011134.1 similar to ref|YP_281004.1| hypothetical membrane spanning protein [Streptococcus pyogenes MGAS6180]; hypothetical protein 366967 6760752 Sez_0347 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002122736.1 366317 R 552526 CDS YP_002122737.1 195977493 6760493 complement(367144..368088) 1 NC_011134.1 similar to ref|YP_001127890.1| CorA-like Mg2+ transporter protein [Streptococcus pyogenes str. Manfredo]; May play a role in the transport of magnesium.; magnesium and cobalt transport protein CorA 368088 corA 6760493 corA Streptococcus equi subsp. zooepidemicus MGCS10565 magnesium and cobalt transport protein CorA YP_002122737.1 367144 R 552526 CDS YP_002122738.1 195977494 6760750 368284..371106 1 NC_011134.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate; excinuclease ABC subunit A 371106 uvrA 6760750 uvrA Streptococcus equi subsp. zooepidemicus MGCS10565 excinuclease ABC subunit A YP_002122738.1 368284 D 552526 CDS YP_002122739.1 195977495 6760492 371684..372781 1 NC_011134.1 similar to ref|YP_060856.1| Xaa-Pro dipeptidase [Streptococcus pyogenes MGAS10394]; The hydrolysis of a peptide bond or bonds within a protein.; aminopeptidase 372781 6760492 Sez_0350 Streptococcus equi subsp. zooepidemicus MGCS10565 aminopeptidase YP_002122739.1 371684 D 552526 CDS YP_002122740.1 195977496 6760748 372824..373285 1 NC_011134.1 similar to ref|YP_060855.1| ComE operon protein 2 [Streptococcus pyogenes MGAS10394]; Catalysis of the reaction: dCMP + H2O = dUMP + NH3, Dispensable for transformability.; dCMP deaminase; late competence protein ComEB 373285 comEB 6760748 comEB Streptococcus equi subsp. zooepidemicus MGCS10565 dCMP deaminase; late competence protein ComEB YP_002122740.1 372824 D 552526 CDS YP_002122741.1 195977497 6760491 373379..373936 1 NC_011134.1 Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA; elongation factor P 373936 efp 6760491 efp Streptococcus equi subsp. zooepidemicus MGCS10565 elongation factor P YP_002122741.1 373379 D 552526 CDS YP_002122742.1 195977498 6760746 373979..374368 1 NC_011134.1 similar to ref|YP_001127895.1| hypothetical protein SpyM50304 [Streptococcus pyogenes str. Manfredo]; general stress protein 374368 6760746 Sez_0353 Streptococcus equi subsp. zooepidemicus MGCS10565 general stress protein YP_002122742.1 373979 D 552526 CDS YP_002122743.1 195977499 6760490 374394..374813 1 NC_011134.1 Regulates rRNA biosynthesis by transcriptional antitermination; transcription antitermination protein NusB 374813 nusB 6760490 nusB Streptococcus equi subsp. zooepidemicus MGCS10565 transcription antitermination protein NusB YP_002122743.1 374394 D 552526 CDS YP_002122744.1 195977500 6760744 375046..375312 1 NC_011134.1 similar to ref|YP_001451052.1| hypothetical protein SGO_1783 [Streptococcus gordonii str. Challis substr. CH1]; hypothetical protein 375312 6760744 Sez_0355 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002122744.1 375046 D 552526 CDS YP_002122745.1 195977501 6760489 375324..375683 1 NC_011134.1 similar to ref|YP_001035341.1| hypothetical protein SSA_1393 [Streptococcus sanguinis SK36]; hypothetical protein 375683 6760489 Sez_0356 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002122745.1 375324 D 552526 CDS YP_002122746.1 195977502 6760742 375674..376573 1 NC_011134.1 similar to ref|YP_001035340.1| hypothetical protein SSA_1392 [Streptococcus sanguinis SK36]; hypothetical protein 376573 6760742 Sez_0357 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002122746.1 375674 D 552526 CDS YP_002122747.1 195977503 6760488 376570..377013 1 NC_011134.1 similar to ref|YP_697958.1| bacteriocin [Clostridium perfringens SM101]; hypothetical protein 377013 6760488 Sez_0358 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002122747.1 376570 D 552526 CDS YP_002122748.1 195977504 6760740 377271..377516 1 NC_011134.1 similar to ref|YP_001035338.1| hypothetical protein SSA_1390 [Streptococcus sanguinis SK36]; hypothetical protein 377516 6760740 Sez_0359 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002122748.1 377271 D 552526 CDS YP_002122749.1 195977505 6760487 377723..377929 1 NC_011134.1 similar to ref|XP_503073.1| hypothetical protein [Yarrowia lipolytica]; hypothetical protein 377929 6760487 Sez_0360 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002122749.1 377723 D 552526 CDS YP_002122750.1 195977506 6760738 complement(377894..378859) 1 NC_011134.1 similar to ref|YP_282907.1| sucrose operon repressor [Streptococcus pyogenes MGAS5005]; Negative regulator of scrB expression.; LacI family transcriptional regulator 378859 scrR 6760738 scrR Streptococcus equi subsp. zooepidemicus MGCS10565 LacI family transcriptional regulator YP_002122750.1 377894 R 552526 CDS YP_002122751.1 195977507 6760485 complement(378864..380303) 1 NC_011134.1 similar to ref|YP_280995.1| sucrose-6-phosphate hydrolase [Streptococcus pyogenes MGAS6180]; Catalysis of the hydrolysis of terminal non-reducing beta-D-fructofuranoside residues in beta-D-fructofuranosides.; sucrose-6-phosphate hydrolase 380303 scrB 6760485 scrB Streptococcus equi subsp. zooepidemicus MGCS10565 sucrose-6-phosphate hydrolase YP_002122751.1 378864 R 552526 CDS YP_002122752.1 195977508 6760736 380582..382465 1 NC_011134.1 similar to ref|YP_001127899.1| Gene info PTS system, sucrose-specific IIABC component [Streptococcus pyogenes str. Manfredo]; The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. This system is involved in sucrose transport.; PTS system sucrose-specific transporter subunit IIABC 382465 scrA 6760736 scrA Streptococcus equi subsp. zooepidemicus MGCS10565 PTS system sucrose-specific transporter subunit IIABC YP_002122752.1 380582 D 552526 CDS YP_002122753.1 195977509 6760484 382695..385730 1 NC_011134.1 similar to ref|NP_665373.1| sucrose-specific PTS permease, enzyme II [Streptococcus pyogenes MGAS315]; Endohydrolysis of the di-N-acetylchitobiosyl unit in high-mannose glycopeptides and glycoproteins. Complex biantennary glycans are the preferred substrates. Tri- and tetraantennary glycans are not hydrolyzed, and high mannose glycans are very poor substrates.; endo-beta-N-acetylglucosaminidase F2 385730 endOF2 6760484 endOF2 Streptococcus equi subsp. zooepidemicus MGCS10565 endo-beta-N-acetylglucosaminidase F2 YP_002122753.1 382695 D 552526 CDS YP_002122754.1 195977510 6760733 386100..386984 1 NC_011134.1 similar to ref|NP_607886.1| secreted endoglycosidase [Streptococcus pyogenes MGAS8232]; Catalysis of the reaction: ATP + D-fructose = ADP + D-fructose 6-phosphate.; fructokinase ScrK 386984 scrK 6760733 scrK Streptococcus equi subsp. zooepidemicus MGCS10565 fructokinase ScrK YP_002122754.1 386100 D 552526 CDS YP_002122755.1 195977511 6760483 387130..388044 1 NC_011134.1 similar to ref|NP_269816.1| mannose-6-phosphate isomerase [Streptococcus pyogenes M1 GAS]; Involved in the conversion of glucose to GDP-L-fucose.; mannose-6-phosphate isomerase 388044 pmi 6760483 pmi Streptococcus equi subsp. zooepidemicus MGCS10565 mannose-6-phosphate isomerase YP_002122755.1 387130 D 552526 CDS YP_002122756.1 195977512 6760731 388422..390950 1 NC_011134.1 functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond SecA1; SecA2 is not essential and seems to play a role in secretion of a subset of proteins; preprotein translocase subunit SecA 390950 secA 6760731 secA Streptococcus equi subsp. zooepidemicus MGCS10565 preprotein translocase subunit SecA YP_002122756.1 388422 D 552526 CDS YP_002122757.1 195977513 6760482 391066..391422 1 NC_011134.1 Catalyzes the formation of holo-ACP, which mediates the essential transfer of acyl fatty acid intermediates during the biosynthesis of fatty acids and lipids; 4'-phosphopantetheinyl transferase 391422 acpS 6760482 acpS Streptococcus equi subsp. zooepidemicus MGCS10565 4'-phosphopantetheinyl transferase YP_002122757.1 391066 D 552526 CDS YP_002122758.1 195977514 6760729 391419..392519 1 NC_011134.1 converts L-alanine to D-alanine which is used in cell wall biosynthesis; binds one pyridoxal phosphate per monomer; forms a homodimer; alanine racemase 392519 alr 6760729 alr Streptococcus equi subsp. zooepidemicus MGCS10565 alanine racemase YP_002122758.1 391419 D 552526 CDS YP_002122759.1 195977515 6760481 392789..394204 1 NC_011134.1 similar to ref|YP_599208.1| Immunogenic secreted protein [Streptococcus pyogenes MGAS10270]; pfam05257, CHAP domain. This domain corresponds to an amidase function, MurNAc-L-Ala amidase. Many of these proteins are involved in cell wall metabolism of bacteria. This domain is found at the N-terminus of the bifunctional Escherichia coli GSP synthetase/GSP amidase, where is functions as a glutathionylspermidine amidase.; hypothetical protein 394204 ispZ 6760481 ispZ Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002122759.1 392789 D 552526 CDS YP_002122760.1 195977516 6760727 394405..398160 1 NC_011134.1 similar to ref|YP_597265.1| Fe3+-siderophore transport protein [Streptococcus pyogenes MGAS9429]; Involoved in iron acquisition.; Fe3+-siderophore transport protein 398160 6760727 Sez_0371 Streptococcus equi subsp. zooepidemicus MGCS10565 Fe3+-siderophore transport protein YP_002122760.1 394405 D 552526 CDS YP_002122761.1 195977517 6760480 398413..399294 1 NC_011134.1 similar to gb|ABI79311.1| heme-binding protein [Streptococcus equi subsp. equi]; heme-binding protein 399294 6760480 Sez_0372 Streptococcus equi subsp. zooepidemicus MGCS10565 heme-binding protein YP_002122761.1 398413 D 552526 CDS YP_002122762.1 195977518 6760725 399278..400162 1 NC_011134.1 similar to gb|ABI79312.1| heme-binding lipoprotein [Streptococcus equi subsp. equi]; Binds citrate-dependent iron(III); part of the binding- protein-dependent transport system for uptake of citrate-dependent iron(III).; ferrichrome ABC transporter substrate-binding lipoprotein 400162 6760725 Sez_0373 Streptococcus equi subsp. zooepidemicus MGCS10565 ferrichrome ABC transporter substrate-binding lipoprotein YP_002122762.1 399278 D 552526 CDS YP_002122763.1 195977519 6760479 400164..401186 1 NC_011134.1 similar to ref|NP_665363.1| ferrichrome ABC transporter (permease) [Streptococcus pyogenes MGAS315]; This is one of the proteins involved in the high- affinity transport of ferrichrome.; heme ABC transporter permease 401186 6760479 Sez_0374 Streptococcus equi subsp. zooepidemicus MGCS10565 heme ABC transporter permease YP_002122763.1 400164 D 552526 CDS YP_002122764.1 195977520 6760722 401183..401965 1 NC_011134.1 similar to ref|YP_060837.1| Ferrichrome transport ATP-binding protein [Streptococcus pyogenes MGAS10394]; Part of the binding-protein-dependent transport system for Fe(3+)-ferrichrome. Probably responsible for energy coupling to the transport system.; heme ABC transporter ATP-binding protein 401965 6760722 Sez_0375 Streptococcus equi subsp. zooepidemicus MGCS10565 heme ABC transporter ATP-binding protein YP_002122764.1 401183 D 552526 CDS YP_002122765.1 195977521 6760478 402011..403774 1 NC_011134.1 similar to ref|NP_607874.1| ABC transporter (ATP-binding protein) [Streptococcus pyogenes MGAS8232]; Component of a transport system.; ABC transporter ATP-binding protein 403774 6760478 Sez_0376 Streptococcus equi subsp. zooepidemicus MGCS10565 ABC transporter ATP-binding protein YP_002122765.1 402011 D 552526 CDS YP_002122766.1 195977522 6760720 403767..405449 1 NC_011134.1 similar to ref|YP_597258.1| ABC transporter ATP-binding protein [Streptococcus pyogenes MGAS9429]; Component of a transport system.; ABC transporter ATP-binding protein 405449 6760720 Sez_0377 Streptococcus equi subsp. zooepidemicus MGCS10565 ABC transporter ATP-binding protein YP_002122766.1 403767 D 552526 CDS YP_002122767.1 195977523 6760477 405430..406023 1 NC_011134.1 similar to ref|NP_607872.1| hypothetical protein spyM18_1861 [Streptococcus pyogenes MGAS8232]; Permease component of an ABC transporter.; ABC transporter permease 406023 6760477 Sez_0378 Streptococcus equi subsp. zooepidemicus MGCS10565 ABC transporter permease YP_002122767.1 405430 D 552526 CDS YP_002122768.1 195977524 6760717 406020..406703 1 NC_011134.1 similar to ref|NP_607871.1| hypothetical protein spyM18_1860 [Streptococcus pyogenes MGAS8232]; Possibly involved in cobalt transport.; transporter 406703 6760717 Sez_0379 Streptococcus equi subsp. zooepidemicus MGCS10565 transporter YP_002122768.1 406020 D 552526 CDS YP_002122769.1 195977525 6760476 406700..408094 1 NC_011134.1 similar to ref|YP_001127916.1| ABC transporter ATP-binding protein [Streptococcus pyogenes str. Manfredo]; Part of the ABC transporter complex possibly involved in cobalt import. Responsible for energy coupling to the transport system.; importer ATP-binding protein 408094 6760476 Sez_0380 Streptococcus equi subsp. zooepidemicus MGCS10565 importer ATP-binding protein YP_002122769.1 406700 D 552526 CDS YP_002122770.1 195977526 6760714 408472..410487 1 NC_011134.1 similar to ref|NP_722150.1| ATP-dependent DNA helicase, RecG [Streptococcus mutans UA159]; Critical role in recombination and DNA repair. Help process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3' to 5' polarity. RecG unwind branched duplex DNA (Y-DNA).; ATP-dependent DNA helicase RecG 410487 recG 6760714 recG Streptococcus equi subsp. zooepidemicus MGCS10565 ATP-dependent DNA helicase RecG YP_002122770.1 408472 D 552526 CDS YP_002122771.1 195977527 6760475 complement(410608..411531) 1 NC_011134.1 similar to ref|NP_269796.1| L-asparaginase [Streptococcus pyogenes M1 GAS]; Catalysis of the reaction: L-asparagine + H2O = L-aspartate + NH3.; L-asparaginase 411531 ansA 6760475 ansA Streptococcus equi subsp. zooepidemicus MGCS10565 L-asparaginase YP_002122771.1 410608 R 552526 CDS YP_002122772.1 195977528 6760711 411645..413033 1 NC_011134.1 similar to ref|ZP_00365596.1| COG0561: Predicted hydrolases of the HAD superfamily [Streptococcus pyogenes M49 591]; hydrolase 413033 6760711 Sez_0383 Streptococcus equi subsp. zooepidemicus MGCS10565 hydrolase YP_002122772.1 411645 D 552526 CDS YP_002122773.1 195977529 6760474 complement(413320..413748) 1 NC_011134.1 similar to ref|YP_280968.1| universal stress protein family [Streptococcus pyogenes MGAS6180]; universal stress protein 413748 6760474 Sez_0384 Streptococcus equi subsp. zooepidemicus MGCS10565 universal stress protein YP_002122773.1 413320 R 552526 CDS YP_002122774.1 195977530 6760473 415432..416214 1 NC_011134.1 CodY; DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase (By similarity). It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor; transcriptional repressor CodY 416214 codY 6760473 codY Streptococcus equi subsp. zooepidemicus MGCS10565 transcriptional repressor CodY YP_002122774.1 415432 D 552526 CDS YP_002122775.1 195977531 6760707 416842..417399 1 NC_011134.1 similar to ref|YP_001034560.1| Isochorismitase family protein, [Streptococcus sanguinis SK36]; Catalysis of the reaction: nicotinamide + H2O = nicotinate + NH3.; pyrazinamidase/nicotinamidase 417399 6760707 Sez_0388 Streptococcus equi subsp. zooepidemicus MGCS10565 pyrazinamidase/nicotinamidase YP_002122775.1 416842 D 552526 CDS YP_002122776.1 195977532 6760471 417881..418183 1 NC_011134.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; some Mycoplasma proteins contain an N-terminal fusion to an unknown domain; aspartyl/glutamyl-tRNA amidotransferase subunit C 418183 gatC 6760471 gatC Streptococcus equi subsp. zooepidemicus MGCS10565 aspartyl/glutamyl-tRNA amidotransferase subunit C YP_002122776.1 417881 D 552526 CDS YP_002122777.1 195977533 6760705 418183..419649 1 NC_011134.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; aspartyl/glutamyl-tRNA amidotransferase subunit A 419649 gatA 6760705 gatA Streptococcus equi subsp. zooepidemicus MGCS10565 aspartyl/glutamyl-tRNA amidotransferase subunit A YP_002122777.1 418183 D 552526 CDS YP_002122778.1 195977534 6760470 419649..421088 1 NC_011134.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; aspartyl/glutamyl-tRNA amidotransferase subunit B 421088 gatB 6760470 gatB Streptococcus equi subsp. zooepidemicus MGCS10565 aspartyl/glutamyl-tRNA amidotransferase subunit B YP_002122778.1 419649 D 552526 CDS YP_002122779.1 195977535 6760703 421317..422261 1 NC_011134.1 similar to ref|YP_820933.1| permease of the drug/metabolite transporter (DMT) superfamily [Streptococcus thermophilus LMD-9]; drug/metabolite transporter (DMT) superfamily protein 422261 6760703 Sez_0392 Streptococcus equi subsp. zooepidemicus MGCS10565 drug/metabolite transporter (DMT) superfamily protein YP_002122779.1 421317 D 552526 CDS YP_002122780.1 195977536 6760469 422309..422551 1 NC_011134.1 similar to ref|YP_060816.1| Hypothetical membrane spanning protein [Streptococcus pyogenes MGAS10394]; hypothetical protein 422551 6760469 Sez_0393 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002122780.1 422309 D 552526 CDS YP_002122781.1 195977537 6760701 422760..423767 1 NC_011134.1 similar to gb|AAD29424.1|AF136451_1 fibronectin-binding protein SFS [Streptococcus equi]; secreted adhesin, however lacks canonical secretion signal sequence. Has some similarity with the eukaryotic ECM protein, repetin.; fibronectin-binding protein Sfs-like 423767 sfs 6760701 sfs Streptococcus equi subsp. zooepidemicus MGCS10565 fibronectin-binding protein Sfs-like YP_002122781.1 422760 D 552526 CDS YP_002122782.1 195977538 6760468 424032..424298 1 NC_011134.1 ACT domain-containing protein; hypothetical protein 424298 6760468 Sez_0395 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002122782.1 424032 D 552526 CDS YP_002122783.1 195977539 6760698 424313..425650 1 NC_011134.1 similar to ref|YP_001449706.1| glycerol-3-phosphate dehydrogenase (NAD(P)+) [Streptococcus gordonii str. Challis substr. CH1]; De novo phospholipid biosynthesis; glycerol-3 phosphate formation.; hypothetical protein 425650 6760698 Sez_0396 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002122783.1 424313 D 552526 CDS YP_002122784.1 195977540 6760467 425767..426432 1 NC_011134.1 similar to ref|NP_607855.1| phosphoglycerate mutase [Streptococcus pyogenes MGAS8232]; phosphoglycerate mutase 426432 6760467 Sez_0397 Streptococcus equi subsp. zooepidemicus MGCS10565 phosphoglycerate mutase YP_002122784.1 425767 D 552526 CDS YP_002122785.1 195977541 6760695 426422..427165 1 NC_011134.1 similar to ref|NP_607854.1| D,D-carboxypeptidase [Streptococcus pyogenes MGAS8232]; Vancomycin-inducible, penicillin-resistant, DD- carboxypeptidase that hydrolyzes depsipeptide- and D-alanyl-D- alanine-containing peptidoglycan precursors. Insensitive to beta- lactams.; D-alanyl-D-alanine carboxypeptidase 427165 6760695 Sez_0398 Streptococcus equi subsp. zooepidemicus MGCS10565 D-alanyl-D-alanine carboxypeptidase YP_002122785.1 426422 D 552526 CDS YP_002122786.1 195977542 6760466 427213..427698 1 NC_011134.1 similar to ref|NP_607853.1| N-acetyl-muramidase [Streptococcus pyogenes MGAS8232]; N-acetyl-muramidase 427698 6760466 Sez_0399 Streptococcus equi subsp. zooepidemicus MGCS10565 N-acetyl-muramidase YP_002122786.1 427213 D 552526 CDS YP_002122787.1 195977543 6760693 428181..429215 1 NC_011134.1 Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons; heat-inducible transcription repressor 429215 hrcA 6760693 hrcA Streptococcus equi subsp. zooepidemicus MGCS10565 heat-inducible transcription repressor YP_002122787.1 428181 D 552526 CDS YP_002122788.1 195977544 6760465 429260..429829 1 NC_011134.1 with DnaK and DnaJ acts in response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins; may act as a thermosensor; heat shock protein GrpE 429829 grpE 6760465 grpE Streptococcus equi subsp. zooepidemicus MGCS10565 heat shock protein GrpE YP_002122788.1 429260 D 552526 CDS YP_002122789.1 195977545 6760691 430217..432070 1 NC_011134.1 heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria; molecular chaperone DnaK 432070 dnaK 6760691 dnaK Streptococcus equi subsp. zooepidemicus MGCS10565 molecular chaperone DnaK YP_002122789.1 430217 D 552526 CDS YP_002122790.1 195977546 6760464 432227..433363 1 NC_011134.1 chaperone Hsp40; co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion; molecular chaperone DnaJ 433363 dnaJ 6760464 dnaJ Streptococcus equi subsp. zooepidemicus MGCS10565 molecular chaperone DnaJ YP_002122790.1 432227 D 552526 CDS YP_002122791.1 195977547 6760688 433621..434481 1 NC_011134.1 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; enoyl-CoA hydratase 434481 6760688 Sez_0404 Streptococcus equi subsp. zooepidemicus MGCS10565 enoyl-CoA hydratase YP_002122791.1 433621 D 552526 CDS YP_002122792.1 195977548 6760463 434561..434995 1 NC_011134.1 similar to ref|YP_280949.1| transcriptional regulator, MarR family [Streptococcus pyogenes MGAS6180]; Transcriptional repressor.; transcriptional regulator of fatty acid biosynthesis FabT 434995 6760463 Sez_0405 Streptococcus equi subsp. zooepidemicus MGCS10565 transcriptional regulator of fatty acid biosynthesis FabT YP_002122792.1 434561 D 552526 CDS YP_002122793.1 195977549 6760685 434995..435969 1 NC_011134.1 FabH; beta-ketoacyl-acyl carrier protein synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs; 3-oxoacyl-ACP synthase 435969 6760685 Sez_0406 Streptococcus equi subsp. zooepidemicus MGCS10565 3-oxoacyl-ACP synthase YP_002122793.1 434995 D 552526 CDS YP_002122794.1 195977550 6760461 436027..436251 1 NC_011134.1 carries the fatty acid chain in fatty acid biosynthesis; acyl carrier protein 436251 acpP 6760461 acpP Streptococcus equi subsp. zooepidemicus MGCS10565 acyl carrier protein YP_002122794.1 436027 D 552526 CDS YP_002122795.1 195977551 6760683 436446..437432 1 NC_011134.1 similar to ref|NP_269774.1| trans-2-enoyl-ACP reductase II [Streptococcus pyogenes M1 GAS]; Catalysis of the reaction: acyl-[acyl-carrier protein] + NAD+ = trans-2,3-dehydroacyl-[acyl-carrier protein] + NADH + H+.; enoyl-ACP reductase 437432 6760683 Sez_0408 Streptococcus equi subsp. zooepidemicus MGCS10565 enoyl-ACP reductase YP_002122795.1 436446 D 552526 CDS YP_002122796.1 195977552 6760460 437445..438365 1 NC_011134.1 similar to ref|NP_269773.1| acyl-carrier-protein S-malonyltransferase [Streptococcus pyogenes M1 GAS]; Fatty acid biosynthesis.; malonyl CoA-ACP transacylase 438365 fabD 6760460 fabD Streptococcus equi subsp. zooepidemicus MGCS10565 malonyl CoA-ACP transacylase YP_002122796.1 437445 D 552526 CDS YP_002122797.1 195977553 6760679 438382..439116 1 NC_011134.1 catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis; 3-ketoacyl-ACP reductase 439116 fabG 6760679 fabG Streptococcus equi subsp. zooepidemicus MGCS10565 3-ketoacyl-ACP reductase YP_002122797.1 438382 D 552526 CDS YP_002122798.1 195977554 6760459 439132..440364 1 NC_011134.1 FabF; beta-ketoacyl-ACP synthase II, KASII; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP; 3-oxoacyl-ACP synthase 440364 fabF 6760459 fabF Streptococcus equi subsp. zooepidemicus MGCS10565 3-oxoacyl-ACP synthase YP_002122798.1 439132 D 552526 CDS YP_002122799.1 195977555 6760676 440366..440839 1 NC_011134.1 composes the biotin carboxyl carrier protein subunit of the acetyl-CoA carboxylase complex, the enzyme that catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, which in turn controls the rate of fatty acid metabolism; acetyl-CoA carboxylase biotin carboxyl carrier protein subunit 440839 accB 6760676 accB Streptococcus equi subsp. zooepidemicus MGCS10565 acetyl-CoA carboxylase biotin carboxyl carrier protein subunit YP_002122799.1 440366 D 552526 CDS YP_002122800.1 195977556 6760458 440836..441258 1 NC_011134.1 in Pseudomonas aeruginosa this enzyme is a trimer of dimers; essential for membrane formation; performs third step of type II fatty acid biosynthesis; catalyzes dehydration of (3R)-hydroxyacyl-ACP to trans-2-acyl-ACP; (3R)-hydroxymyristoyl-ACP dehydratase 441258 fabZ 6760458 fabZ Streptococcus equi subsp. zooepidemicus MGCS10565 (3R)-hydroxymyristoyl-ACP dehydratase YP_002122800.1 440836 D 552526 CDS YP_002122801.1 195977557 6760457 442665..443531 1 NC_011134.1 catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer of AccA2D2 subunits; acetyl-CoA carboxylase subunit beta 443531 accD 6760457 accD Streptococcus equi subsp. zooepidemicus MGCS10565 acetyl-CoA carboxylase subunit beta YP_002122801.1 442665 D 552526 CDS YP_002122802.1 195977558 6760672 443528..444298 1 NC_011134.1 catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer composed of two alpha (AccA) and two beta (AccD) subunits; one of the two catalytic subunits that can form the acetyl CoA carboxylase enzyme together with a carrier protein; these proteins present a shorter N-terminus; acetyl-CoA carboxylase subunit alpha 444298 accA 6760672 accA Streptococcus equi subsp. zooepidemicus MGCS10565 acetyl-CoA carboxylase subunit alpha YP_002122802.1 443528 D 552526 CDS YP_002122803.1 195977559 6760456 complement(444529..445806) 1 NC_011134.1 catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; seryl-tRNA synthetase 445806 serS 6760456 serS Streptococcus equi subsp. zooepidemicus MGCS10565 seryl-tRNA synthetase YP_002122803.1 444529 R 552526 CDS YP_002122804.1 195977560 6760670 446391..447458 1 NC_011134.1 similar to ref|NP_734813.1| hypothetical protein gbs0344 [Streptococcus agalactiae NEM316]; hypothetical protein 447458 6760670 Sez_0419 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002122804.1 446391 D 552526 CDS YP_002122805.1 195977561 6760455 complement(447626..448009) 1 NC_011134.1 similar to ref|YP_280936.1| hypothetical cytosolic protein [Streptococcus pyogenes MGAS6180]; mannose operon regulator ManO 448009 manO 6760455 manO Streptococcus equi subsp. zooepidemicus MGCS10565 mannose operon regulator ManO YP_002122805.1 447626 R 552526 CDS YP_002122806.1 195977562 6760668 complement(448143..449054) 1 NC_011134.1 similar to ref|NP_607833.1| mannose-specific phosphotransferase system component IID [Streptococcus pyogenes MGAS8232]; This is a component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (Pts), a major carbohydrate active -transport system.; mannose-Specific Phosphotransferase System Component IID ManZ 449054 manZ 6760668 manZ Streptococcus equi subsp. zooepidemicus MGCS10565 mannose-Specific Phosphotransferase System Component IID ManZ YP_002122806.1 448143 R 552526 CDS YP_002122807.1 195977563 6760454 complement(449070..449879) 1 NC_011134.1 similar to ref|YP_280934.1| PTS system, mannose-specific IIC component [Streptococcus pyogenes MGAS6180]; PTS system mannose-specific transporter subunit IIC 449879 manY 6760454 manY Streptococcus equi subsp. zooepidemicus MGCS10565 PTS system mannose-specific transporter subunit IIC YP_002122807.1 449070 R 552526 CDS YP_002122808.1 195977564 6760666 complement(450047..451039) 1 NC_011134.1 similar to ref|YP_001127956.1| mannose-specific phosphotransferase system (PTS), IIAB component [Streptococcus pyogenes str. Manfredo]; The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. This system is involved in mannose transport.; PTS system mannose-specific transporter subunit IIAB 451039 manX 6760666 manX Streptococcus equi subsp. zooepidemicus MGCS10565 PTS system mannose-specific transporter subunit IIAB YP_002122808.1 450047 R 552526 CDS YP_002122809.1 195977565 6760453 complement(451167..451394) 1 NC_011134.1 similar to ref|XP_954798.1| glutamate-cysteine ligase, [Theileria annulata strain Ankara]; hypothetical protein 451394 6760453 Sez_0424 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002122809.1 451167 R 552526 CDS YP_002122810.1 195977566 6760663 complement(451391..452203) 1 NC_011134.1 similar to ref|NP_607830.1| hypothetical protein spyM18_1809 [Streptococcus pyogenes MGAS8232]; hydrolase 452203 6760663 Sez_0425 Streptococcus equi subsp. zooepidemicus MGCS10565 hydrolase YP_002122810.1 451391 R 552526 CDS YP_002122811.1 195977567 6760452 452462..453922 1 NC_011134.1 similar to ref|YP_060789.1| Guanine-hypoxanthine permease [Streptococcus pyogenes MGAS10394]; guanine-hypoxanthine permease 453922 6760452 Sez_0426 Streptococcus equi subsp. zooepidemicus MGCS10565 guanine-hypoxanthine permease YP_002122811.1 452462 D 552526 CDS YP_002122812.1 195977568 6760661 454291..454734 1 NC_011134.1 similar to ref|NP_720857.1| hypothetical protein SMU.409 [Streptococcus mutans UA159]; Similar to ATPase YjeE, predicted to have essential role in cell wall biosynthesis.; ATP/GTP hydrolase 454734 6760661 Sez_0427 Streptococcus equi subsp. zooepidemicus MGCS10565 ATP/GTP hydrolase YP_002122812.1 454291 D 552526 CDS YP_002122813.1 195977569 6760451 454727..455254 1 NC_011134.1 similar to ref|NP_607771.1| hypothetical protein spyM18_1742 [Streptococcus pyogenes MGAS8232]; acetyltransferase GNAT Family 455254 6760451 Sez_0428 Streptococcus equi subsp. zooepidemicus MGCS10565 acetyltransferase GNAT Family YP_002122813.1 454727 D 552526 CDS YP_002122814.1 195977570 6760659 455255..456517 1 NC_011134.1 similar to ref|YP_060786.1| Transcriptional regulator, LytR family [Streptococcus pyogenes MGAS10394]; Attenuator role for operon expression.; LytR family transcriptional regulator 456517 lytR 6760659 lytR Streptococcus equi subsp. zooepidemicus MGCS10565 LytR family transcriptional regulator YP_002122814.1 455255 D 552526 CDS YP_002122815.1 195977571 6760450 complement(456681..456983) 1 NC_011134.1 similar to ref|NP_607769.1| hypothetical protein spyM18_1739 [Streptococcus pyogenes MGAS8232]; hypothetical protein 456983 6760450 Sez_0430 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002122815.1 456681 R 552526 CDS YP_002122816.1 195977572 6760657 complement(456980..457399) 1 NC_011134.1 similar to ref|NP_269754.1| cell-cycle regulation histidine triad (HIT) protein [Streptococcus pyogenes M1 GAS]; cell-cycle regulation histidine triad protein HIT 457399 hit 6760657 hit Streptococcus equi subsp. zooepidemicus MGCS10565 cell-cycle regulation histidine triad protein HIT YP_002122816.1 456980 R 552526 CDS YP_002122817.1 195977573 6760449 complement(457851..458147) 1 NC_011134.1 similar to ref|YP_040351.1| hypothetical protein SAR0929 [Staphylococcus aureus subsp. aureus MRSA252]; hypothetical protein 458147 6760449 Sez_0432 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002122817.1 457851 R 552526 CDS YP_002122818.1 195977574 6760654 complement(458445..458588) 1 NC_011134.1 hypothetical protein 458588 6760654 Sez_0433 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002122818.1 458445 R 552526 CDS YP_002122819.1 195977575 6760448 458684..459388 1 NC_011134.1 similar to ref|YP_280925.1| ABC-type transporter ATP-binding protein ecsA [Streptococcus pyogenes MGAS6180]; Has a role in exoprotein production, sporulation and competence.; ABC transporter ATP-binding protein 459388 ecsA 6760448 ecsA Streptococcus equi subsp. zooepidemicus MGCS10565 ABC transporter ATP-binding protein YP_002122819.1 458684 D 552526 CDS YP_002122820.1 195977576 6760652 459412..460446 1 NC_011134.1 similar to ref|YP_060782.1| EcsB [Streptococcus pyogenes MGAS10394]; Strain 3610 ecsB deletion mutant forms colonies in which certain architectural features are absent or less prominent than those observed in wild-type colonies. The Ecs activity could be important for the development of communities.; EcsB 460446 ecsB 6760652 ecsB Streptococcus equi subsp. zooepidemicus MGCS10565 EcsB YP_002122820.1 459412 D 552526 CDS YP_002122821.1 195977577 6760447 460509..461300 1 NC_011134.1 similar to ref|YP_060781.1| Phosphotransferase enzyme family [Streptococcus pyogenes MGAS10394]; aminoglycoside phosphotransferase 461300 6760447 Sez_0436 Streptococcus equi subsp. zooepidemicus MGCS10565 aminoglycoside phosphotransferase YP_002122821.1 460509 D 552526 CDS YP_002122822.1 195977578 6760650 461300..461935 1 NC_011134.1 tRNA (guanine-N(7)-)-methyltransferase; catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA by transferring the methyl residue from S-adenosyl-L-methionine; tRNA (guanine-N(7)-)-methyltransferase 461935 trmB 6760650 trmB Streptococcus equi subsp. zooepidemicus MGCS10565 tRNA (guanine-N(7)-)-methyltransferase YP_002122822.1 461300 D 552526 CDS YP_002122823.1 195977579 6760816 complement(462131..462283) 1 NC_011134.1 similar to ref|YP_282830.1| Gene info phi5005.3 integrase [Streptococcus pyogenes phage 5005.3]; phage integrase-like protein 462283 6760816 Sez_0438 Streptococcus equi subsp. zooepidemicus MGCS10565 phage integrase-like protein YP_002122823.1 462131 R 552526 CDS YP_002122824.1 195977580 6760648 463417..463800 1 NC_011134.1 in Streptococcus pneumoniae this gene was found to be essential; structure determination of the Streptococcus protein shows that it is similar to a number of other proteins; hypothetical protein 463800 6760648 Sez_0439 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002122824.1 463417 D 552526 CDS YP_002122825.1 195977581 6760445 463910..465064 1 NC_011134.1 modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination; transcription elongation factor NusA 465064 nusA 6760445 nusA Streptococcus equi subsp. zooepidemicus MGCS10565 transcription elongation factor NusA YP_002122825.1 463910 D 552526 CDS YP_002122826.1 195977582 6760646 465080..465376 1 NC_011134.1 similar to ref|YP_060777.1| Hypothetical cytosolic protein [Streptococcus pyogenes MGAS10394]; COG2740: Predicted nucleic-acid-binding protein implicated in transcription termination.; hypothetical protein 465376 6760646 Sez_0441 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002122826.1 465080 D 552526 CDS YP_002122827.1 195977583 6760444 465396..465671 1 NC_011134.1 similar to ref|NP_607760.1| hypothetical protein spyM18_1730 [Streptococcus pyogenes MGAS8232]; ribosomal protein L7Ae family protein 465671 6760444 Sez_0442 Streptococcus equi subsp. zooepidemicus MGCS10565 ribosomal protein L7Ae family protein YP_002122827.1 465396 D 552526 CDS YP_002122828.1 195977584 6760644 465691..468534 1 NC_011134.1 Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; translation initiation factor IF-2 468534 infB 6760644 infB Streptococcus equi subsp. zooepidemicus MGCS10565 translation initiation factor IF-2 YP_002122828.1 465691 D 552526 CDS YP_002122829.1 195977585 6760443 complement(468585..468725) 1 NC_011134.1 hypothetical protein 468725 6760443 Sez_0444 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002122829.1 468585 R 552526 CDS YP_002122830.1 195977586 6760642 468724..469074 1 NC_011134.1 associates with free 30S ribosomal subunits; essential for efficient processing of 16S rRNA; in Escherichia coli rbfA is induced by cold shock; ribosome-binding factor A 469074 rbfA 6760642 rbfA Streptococcus equi subsp. zooepidemicus MGCS10565 ribosome-binding factor A YP_002122830.1 468724 D 552526 CDS YP_002122831.1 195977587 6760442 complement(469146..470183) 1 NC_011134.1 similar to ref|ZP_00365884.1| COG0657: Esterase/lipase [Streptococcus pyogenes M49 591]; Unknown, similar to beta lactamases, possibly involved in PG maturation.; esterase 470183 6760442 Sez_0446 Streptococcus equi subsp. zooepidemicus MGCS10565 esterase YP_002122831.1 469146 R 552526 CDS YP_002122832.1 195977588 6760640 470413..470847 1 NC_011134.1 similar to ref|YP_280914.1| copAB ATPase metal-fist type repressor [Streptococcus pyogenes MGAS6180]; negative transcriptional regulator-copper transport operon 470847 6760640 Sez_0447 Streptococcus equi subsp. zooepidemicus MGCS10565 negative transcriptional regulator-copper transport operon YP_002122832.1 470413 D 552526 CDS YP_002122833.1 195977589 6760441 470817..473078 1 NC_011134.1 similar to ref|YP_597138.1| copper-exporting ATPase [Streptococcus pyogenes MGAS9429]; May play a role in the osmotic adaptation.; copper-translocating P-type ATPase PacS 473078 pacS 6760441 pacS Streptococcus equi subsp. zooepidemicus MGCS10565 copper-translocating P-type ATPase PacS YP_002122833.1 470817 D 552526 CDS YP_002122834.1 195977590 6760638 complement(473474..473596) 1 NC_011134.1 hypothetical protein 473596 6760638 Sez_0449 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002122834.1 473474 R 552526 CDS YP_002122835.1 195977591 6760440 473949..474899 1 NC_011134.1 similar to ref|YP_001052596.1| hypothetical protein Sbal_4262 [Shewanella baltica OS155]; Unknown, possible galanin.; hypothetical protein 474899 6760440 Sez_0450 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002122835.1 473949 D 552526 CDS YP_002122836.1 195977592 6760636 474912..475463 1 NC_011134.1 similar to ref|YP_001395827.1| hypothetical protein CKL_2444 [Clostridium kluyveri DSM 555]; The members of this family are related to the LemA protein . LemA contains an N-terminal predicted transmembrane helix. It has been predicted that the small N terminus is extracellular. The exact molecular function of this protein is uncertain.; LemA family protein 475463 6760636 Sez_0451 Streptococcus equi subsp. zooepidemicus MGCS10565 LemA family protein YP_002122836.1 474912 D 552526 CDS YP_002122837.1 195977593 6760439 complement(475879..476661) 1 NC_011134.1 similar to ref|YP_597136.1| lactose phosphotransferase system repressor [Streptococcus pyogenes MGAS9429]; Repressor of the lactose catabolism operon. Galactose-6- phosphate is the inducer.; lactose phosphotransferase system repressor LacR 476661 lacR 6760439 lacR Streptococcus equi subsp. zooepidemicus MGCS10565 lactose phosphotransferase system repressor LacR YP_002122837.1 475879 R 552526 CDS YP_002122838.1 195977594 6761368 476862..477287 1 NC_011134.1 catalyzes the interconversion of galactose 6-phosphate to tagatose; galactose-6-phosphate isomerase subunit LacA 477287 lacA 6761368 lacA Streptococcus equi subsp. zooepidemicus MGCS10565 galactose-6-phosphate isomerase subunit LacA YP_002122838.1 476862 D 552526 CDS YP_002122839.1 195977595 6761366 477303..477818 1 NC_011134.1 catalyzes the interconversion of galactose 6-phosphate to tagatose 6-phosphate; galactose-6-phosphate isomerase subunit LacB 477818 lacB 6761366 lacB Streptococcus equi subsp. zooepidemicus MGCS10565 galactose-6-phosphate isomerase subunit LacB YP_002122839.1 477303 D 552526 CDS YP_002122840.1 195977596 6761348 477827..478759 1 NC_011134.1 similar to ref|YP_417532.1| tagatose-6-phosphate kinase [Staphylococcus aureus RF122]; Catalysis of the reaction: ATP + D-fructose 1-phosphate = ADP + D-fructose 1,6-bisphosphate; tagatose-6-phosphate kinase LacC 478759 lacC 6761348 lacC Streptococcus equi subsp. zooepidemicus MGCS10565 tagatose-6-phosphate kinase LacC YP_002122840.1 477827 D 552526 CDS YP_002122841.1 195977597 6761363 478761..479753 1 NC_011134.1 catalyzes the reversible reaction of dihydroxyacetone phosphate with glyceraldehyde 3-phosphate to produce tagatose 1,6-bisphosphate; in Streptococcus pyogenes there are two paralogs of tagatose-bisphosphate aldolase, encoded by lacD1 and lacD2; expression of lacD1 is highly regulated by environmental conditions while lacD2 specializes in an efficient utilization of carbohydrate sources; tagatose 1,6-diphosphate aldolase 479753 lacD 6761363 lacD Streptococcus equi subsp. zooepidemicus MGCS10565 tagatose 1,6-diphosphate aldolase YP_002122841.1 478761 D 552526 CDS YP_002122842.1 195977598 6761361 479789..479914 1 NC_011134.1 hypothetical protein 479914 6761361 Sez_0457 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002122842.1 479789 D 552526 CDS YP_002122843.1 195977599 6761360 480030..480881 1 NC_011134.1 similar to ref|YP_001198405.1| Transcriptional antiterminator [Streptococcus suis 05ZYH33]; Mediates positive regulation of the lac operon by functioning as an antiterminator factor of transcription.; transcription antiterminator LacT 480881 lacT 6761360 lacT Streptococcus equi subsp. zooepidemicus MGCS10565 transcription antiterminator LacT YP_002122843.1 480030 D 552526 CDS YP_002122844.1 195977600 6761353 480892..481203 1 NC_011134.1 similar to ref|YP_001198404.1| Phosphotransferase system cellobiose-specific component IIA [Streptococcus suis 05ZYH33]; The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. This system is involved in lactose transport.; lactose-specific phosphotransferase enzyme IIA component LacF 481203 lacF 6761353 lacF Streptococcus equi subsp. zooepidemicus MGCS10565 lactose-specific phosphotransferase enzyme IIA component LacF YP_002122844.1 480892 D 552526 CDS YP_002122845.1 195977601 6761352 481207..482889 1 NC_011134.1 similar to ref|YP_599311.1| PTS system, lactose-specific IIBC component [Streptococcus pyogenes MGAS10270]; The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. This system is involved in lactose transport.; PTS system lactose-specific transporter subunit IIBC 482889 lacE 6761352 lacE Streptococcus equi subsp. zooepidemicus MGCS10565 PTS system lactose-specific transporter subunit IIBC YP_002122845.1 481207 D 552526 CDS YP_002122846.1 195977602 6761327 482899..484308 1 NC_011134.1 catalyzes the formation of 6-phospho-galactose from a 6-phospho-beta-galactoside; 6-phospho-beta-galactosidase 484308 lacG 6761327 lacG Streptococcus equi subsp. zooepidemicus MGCS10565 6-phospho-beta-galactosidase YP_002122846.1 482899 D 552526 CDS YP_002122847.1 195977603 6761340 484516..485391 1 NC_011134.1 similar to ref|NP_973373.1| lipoprotein, [Treponema denticola ATCC 35405]; membrane associated protein 485391 6761340 Sez_0462 Streptococcus equi subsp. zooepidemicus MGCS10565 membrane associated protein YP_002122847.1 484516 D 552526 CDS YP_002122848.1 195977604 6761339 485549..486151 1 NC_011134.1 similar to ref|YP_060761.1| Hypothetical membrane spanning protein [Streptococcus pyogenes MGAS10394]; rhomboid family integral membrane protein 486151 6761339 Sez_0463 Streptococcus equi subsp. zooepidemicus MGCS10565 rhomboid family integral membrane protein YP_002122848.1 485549 D 552526 CDS YP_002122849.1 195977605 6761338 486156..486980 1 NC_011134.1 similar to ref|NP_607744.1| hypothetical protein spyM18_1711 [Streptococcus pyogenes MGAS8232]; HAD superfamily hydrolase 486980 6761338 Sez_0464 Streptococcus equi subsp. zooepidemicus MGCS10565 HAD superfamily hydrolase YP_002122849.1 486156 D 552526 CDS YP_002122850.1 195977606 6761313 complement(487390..487947) 1 NC_011134.1 similar to ref|YP_060759.1| Transcriptional regulator, TetR family [Streptococcus pyogenes MGAS10394]; TetR family transcriptional regulator 487947 6761313 Sez_0465 Streptococcus equi subsp. zooepidemicus MGCS10565 TetR family transcriptional regulator YP_002122850.1 487390 R 552526 CDS YP_002122851.1 195977607 6761326 488079..488921 1 NC_011134.1 similar to ref|YP_060758.1| DegV family protein [Streptococcus pyogenes MGAS10394]; The structure of this protein revealed a bound fatty-acid molecule in a pocket between the two protein domains. The structure indicates that this family has the molecular function of fatty-acid binding and may play a role in the cellular functions of fatty acid transport or metabolism.; DegV family protein 488921 6761326 Sez_0466 Streptococcus equi subsp. zooepidemicus MGCS10565 DegV family protein YP_002122851.1 488079 D 552526 CDS YP_002122852.1 195977608 6761304 489065..489205 1 NC_011134.1 hypothetical protein 489205 6761304 Sez_0467 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002122852.1 489065 D 552526 CDS YP_002122853.1 195977609 6761320 489192..490175 1 NC_011134.1 similar to ref|NP_664990.1| ribose transport operon repressor [Streptococcus pyogenes MGAS315]; Transcriptional repressor for the ribose rbsDACBK operon.; ribose operon repressor RbsR 490175 rbsR 6761320 rbsR Streptococcus equi subsp. zooepidemicus MGCS10565 ribose operon repressor RbsR YP_002122853.1 489192 D 552526 CDS YP_002122854.1 195977610 6761319 490201..491079 1 NC_011134.1 similar to ref|ZP_00783282.1| ribokinase [Streptococcus agalactiae H36B]; Ribose metabolism; first step.; ribokinase RbsK 491079 rbsK 6761319 rbsK Streptococcus equi subsp. zooepidemicus MGCS10565 ribokinase RbsK YP_002122854.1 490201 D 552526 CDS YP_002122855.1 195977611 6761314 491045..491452 1 NC_011134.1 cytoplasmic mutarotase that catalyzes the conversion between beta-pyran and beta-furan forms of D-ribose; RbsD is required for efficient ribose utilization in E. coli; rbsD-mutant E. coli strains are unable to use ribose as a sole carbon source; D-ribose pyranase 491452 rbsD 6761314 rbsD Streptococcus equi subsp. zooepidemicus MGCS10565 D-ribose pyranase YP_002122855.1 491045 D 552526 CDS YP_002122856.1 195977612 6761281 491468..492946 1 NC_011134.1 similar to ref|YP_328841.1| ribose ABC transporter, ATP-binding protein [Streptococcus agalactiae A909]; Part of the binding-protein-dependent transport system for ribose. Probably responsible for energy coupling to the transport system.; ribose transport ATP-binding protein RbsA 492946 rbsA 6761281 rbsA Streptococcus equi subsp. zooepidemicus MGCS10565 ribose transport ATP-binding protein RbsA YP_002122856.1 491468 D 552526 CDS YP_002122857.1 195977613 6761312 492948..493889 1 NC_011134.1 similar to ref|ZP_00783299.1| ribose ABC transporter, permease [Streptococcus agalactiae H36B]; Part of the binding-protein-dependent transport system for ribose. Probably responsible for the translocation of the substrate across the membrane.; ribose transport system permease RbsC 493889 rbsC 6761312 rbsC Streptococcus equi subsp. zooepidemicus MGCS10565 ribose transport system permease RbsC YP_002122857.1 492948 D 552526 CDS YP_002122858.1 195977614 6761311 493904..494872 1 NC_011134.1 similar to ref|YP_328839.1| ribose ABC transporter, ribose-binding protein [Streptococcus agalactiae A909]; Involved in the high-affinity D-ribose membrane transport system.; D-ribose-binding protein precursor RbsB 494872 rbsB 6761311 rbsB Streptococcus equi subsp. zooepidemicus MGCS10565 D-ribose-binding protein precursor RbsB YP_002122858.1 493904 D 552526 CDS YP_002122859.1 195977615 6761277 495181..495351 1 NC_011134.1 hypothetical protein 495351 6761277 Sez_0474 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002122859.1 495181 D 552526 CDS YP_002122860.1 195977616 6761309 complement(495492..496244) 1 NC_011134.1 similar to ref|YP_597122.1| hypothetical protein MGAS9429_Spy1390 [Streptococcus pyogenes MGAS9429]; Has carboxy terminal proline rich repeat motif.; hypothetical protein 496244 6761309 Sez_0475 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002122860.1 495492 R 552526 CDS YP_002122861.1 195977617 6761307 496435..498066 1 NC_011134.1 similar to ref|YP_597120.1| sodium-dependent phosphate transporter [Streptococcus pyogenes MGAS9429]; Na/Pi-cotransporter family protein 498066 6761307 Sez_0476 Streptococcus equi subsp. zooepidemicus MGCS10565 Na/Pi-cotransporter family protein YP_002122861.1 496435 D 552526 CDS YP_002122862.1 195977618 6761308 498183..499331 1 NC_011134.1 similar to ref|YP_001127991.1| N-acetylglucosamine-6-phosphate deacetylase [Streptococcus pyogenes str. Manfredo]; Catalysis of the reaction: N-acetyl-D-glucosamine 6-phosphate + H2O = D-glucosamine 6-phosphate + acetate.; N-acetylglucosamine-6-phosphate deacetylase 499331 manD 6761308 manD Streptococcus equi subsp. zooepidemicus MGCS10565 N-acetylglucosamine-6-phosphate deacetylase YP_002122862.1 498183 D 552526 CDS YP_002122863.1 195977619 6761272 499418..500257 1 NC_011134.1 similar to ref|YP_597118.1| aldo/keto reductase family [Streptococcus pyogenes MGAS9429]; Catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced.; 2,5-diketo-D-gluconic acid reductase 500257 6761272 Sez_0478 Streptococcus equi subsp. zooepidemicus MGCS10565 2,5-diketo-D-gluconic acid reductase YP_002122863.1 499418 D 552526 CDS YP_002122864.1 195977620 6761301 500528..500911 1 NC_011134.1 similar to gb|ABO37817.1| unknown [Lactococcus garvieae]; hypothetical protein 500911 6761301 Sez_0479 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002122864.1 500528 D 552526 CDS YP_002122865.1 195977621 6761300 500835..501887 1 NC_011134.1 similar to ref|YP_001485591.1| hypothetical membrane protein [Bacillus pumilus SAFR-032]; hypothetical protein 501887 6761300 Sez_0480 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002122865.1 500835 D 552526 CDS YP_002122866.1 195977622 6761299 501884..503131 1 NC_011134.1 similar to ref|YP_035932.1| conserved hypothetical protein, possible permease [Bacillus thuringiensis serovar konkukian str. 97-27]; permease 503131 6761299 Sez_0481 Streptococcus equi subsp. zooepidemicus MGCS10565 permease YP_002122866.1 501884 D 552526 CDS YP_002122867.1 195977623 6761296 503151..503783 1 NC_011134.1 similar to ref|YP_001642502.1| ABC transporter related [Bacillus weihenstephanensis KBAB4]; Part of the ABC transporter complex possibly involved in bacitracin export. Responsible for energy coupling to the transport system.; export ATP-binding protein 503783 6761296 Sez_0482 Streptococcus equi subsp. zooepidemicus MGCS10565 export ATP-binding protein YP_002122867.1 503151 D 552526 CDS YP_002122868.1 195977624 6761295 503752..503913 1 NC_011134.1 hypothetical protein 503913 6761295 Sez_0483 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002122868.1 503752 D 552526 CDS YP_002122869.1 195977625 6761294 504050..504583 1 NC_011134.1 similar to ref|YP_280894.1| hypothetical membrane spanning protein [Streptococcus pyogenes MGAS6180]; hypothetical protein 504583 6761294 Sez_0484 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002122869.1 504050 D 552526 CDS YP_002122870.1 195977626 6761280 complement(504820..504972) 1 NC_011134.1 hypothetical protein 504972 6761280 Sez_0485 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002122870.1 504820 R 552526 CDS YP_002122871.1 195977627 6761291 504971..505882 1 NC_011134.1 glycine--tRNA ligase alpha chain; GlyRS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; glycyl-tRNA synthetase subunit alpha 505882 glyQ 6761291 glyQ Streptococcus equi subsp. zooepidemicus MGCS10565 glycyl-tRNA synthetase subunit alpha YP_002122871.1 504971 D 552526 CDS YP_002122872.1 195977628 6761279 506249..508291 1 NC_011134.1 glycine--tRNA ligase beta chain; glyS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; glycyl-tRNA synthetase subunit beta 508291 glyS 6761279 glyS Streptococcus equi subsp. zooepidemicus MGCS10565 glycyl-tRNA synthetase subunit beta YP_002122872.1 506249 D 552526 CDS YP_002122873.1 195977629 6761276 complement(508284..508415) 1 NC_011134.1 hypothetical protein 508415 6761276 Sez_0488 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002122873.1 508284 R 552526 CDS YP_002122874.1 195977630 6761289 508829..509086 1 NC_011134.1 similar to ref|NP_269721.1| hypothetical protein SPy_1687 [Streptococcus pyogenes M1 GAS]; hypothetical protein 509086 6761289 Sez_0489 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002122874.1 508829 D 552526 CDS YP_002122875.1 195977631 6761287 509615..509776 1 NC_011134.1 similar to gb|AAC19115.1| streptolysin S associated protein SagA [Streptococcus pyogenes]; Hemolysin/cytolysin.; SagA precursor 509776 sagA 6761287 sagA Streptococcus equi subsp. zooepidemicus MGCS10565 SagA precursor YP_002122875.1 509615 D 552526 CDS YP_002122876.1 195977632 6761275 510004..510954 1 NC_011134.1 similar to gb|AAK53984.1| SagB [Streptococcus dysgalactiae subsp. equisimilis]; Involved in streptolysin S synthesis/transport/immunity.; Streptolysin S biosynthesis protein SagB 510954 sagB 6761275 sagB Streptococcus equi subsp. zooepidemicus MGCS10565 Streptolysin S biosynthesis protein SagB YP_002122876.1 510004 D 552526 CDS YP_002122877.1 195977633 6761256 510951..512015 1 NC_011134.1 similar to gb|AAN16973.1|AF465842_3 SagC [Streptococcus iniae]; Involved in streptolysin S synthesis/transport/immunity.; Streptolysin S biosynthesis protein SagC 512015 sagC 6761256 sagC Streptococcus equi subsp. zooepidemicus MGCS10565 Streptolysin S biosynthesis protein SagC YP_002122877.1 510951 D 552526 CDS YP_002122878.1 195977634 6761271 512028..513386 1 NC_011134.1 similar to ref|YP_598228.1| Streptolysin S biosynthesis protein SagD [Streptococcus pyogenes MGAS10270]; Involved in streptolysin S synthesis/transport/immunity.; Streptolysin S biosynthesis protein SagD 513386 sagD 6761271 sagD Streptococcus equi subsp. zooepidemicus MGCS10565 Streptolysin S biosynthesis protein SagD YP_002122878.1 512028 D 552526 CDS YP_002122879.1 195977635 6761253 513427..514032 1 NC_011134.1 similar to gb|AAN16975.1|AF465842_5 SagE [Streptococcus iniae]; Involved in streptolysin S synthesis/transport/immunity.; Streptolysin S self-immunity protein SagE 514032 sagE 6761253 sagE Streptococcus equi subsp. zooepidemicus MGCS10565 Streptolysin S self-immunity protein SagE YP_002122879.1 513427 D 552526 CDS YP_002122880.1 195977636 6761250 514029..514715 1 NC_011134.1 similar to gb|AAN16976.1|AF465842_6 SagF [Streptococcus iniae]; Involved in streptolysin S synthesis/transport/immunity.; Streptolysin S biosynthesis protein SagF 514715 sagF 6761250 sagF Streptococcus equi subsp. zooepidemicus MGCS10565 Streptolysin S biosynthesis protein SagF YP_002122880.1 514029 D 552526 CDS YP_002122881.1 195977637 6761249 514738..515661 1 NC_011134.1 similar to gb|AAN16977.1|AF465842_7 SagG [Streptococcus iniae]; Involved in streptolysin S synthesis/transport/immunity.; export ABC transporter ATP-binding protein; Streptolysin S export protein SagG 515661 sagG 6761249 sagG Streptococcus equi subsp. zooepidemicus MGCS10565 export ABC transporter ATP-binding protein; Streptolysin S export protein SagG YP_002122881.1 514738 D 552526 CDS YP_002122882.1 195977638 6761248 515670..516797 1 NC_011134.1 similar to gb|AAN16978.1|AF465842_8 SagH [Streptococcus iniae]; Involved in streptolysin S synthesis/transport/immunity.; Streptolysin S export transmembrane permease SagH 516797 sagH 6761248 sagH Streptococcus equi subsp. zooepidemicus MGCS10565 Streptolysin S export transmembrane permease SagH YP_002122882.1 515670 D 552526 CDS YP_002122883.1 195977639 6761266 516794..517912 1 NC_011134.1 similar to gb|AAN16979.1|AF465842_9 SagI [Streptococcus iniae]; Involved in streptolysin S synthesis/transport/immunity.; Streptolysin S export transmembrane permease SagI 517912 sagI 6761266 sagI Streptococcus equi subsp. zooepidemicus MGCS10565 Streptolysin S export transmembrane permease SagI YP_002122883.1 516794 D 552526 CDS YP_002122884.1 195977640 6761267 complement(518045..519493) 1 NC_011134.1 similar to ref|NP_001105492.1| proline-rich protein [Zea mays]; fibronectin-binding protein FbpZ.2 519493 fbpZ.2 6761267 fbpZ.2 Streptococcus equi subsp. zooepidemicus MGCS10565 fibronectin-binding protein FbpZ.2 YP_002122884.1 518045 R 552526 CDS YP_002122885.1 195977641 6761261 complement(519809..521377) 1 NC_011134.1 similar to gb|ABA41496.1| collagen-like protein F [Streptococcus equi subsp. equi]; Possible fibronectin-binding adhesin, has a collagen-structural-motif domain composed of 51 Gly-Xaa-Yaa repeats.; hypothetical protein 521377 sclZ.6 6761261 sclZ.6 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002122885.1 519809 R 552526 CDS YP_002122886.1 195977642 6761241 complement(521396..521521) 1 NC_011134.1 hypothetical protein 521521 6761241 Sez_0501 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002122886.1 521396 R 552526 CDS YP_002122887.1 195977643 6761260 521527..521658 1 NC_011134.1 hypothetical protein 521658 6761260 Sez_0502 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002122887.1 521527 D 552526 CDS YP_002122888.1 195977644 6761239 complement(521790..522875) 1 NC_011134.1 similar to gb|AAN18300.1| lipoprotein [Streptococcus equi]; hypothetical protein 522875 6761239 Sez_0503 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002122888.1 521790 R 552526 CDS YP_002122889.1 195977645 6761232 523112..523240 1 NC_011134.1 hypothetical protein 523240 6761232 Sez_0504 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002122889.1 523112 D 552526 CDS YP_002122890.1 195977646 6761236 complement(523347..523976) 1 NC_011134.1 similar to gb|AAN18302.1| Se22.9 [Streptococcus equi]; Involved in copper homeostasis.; copper homeostasis protein CutC-like 523976 cutC 6761236 cutC Streptococcus equi subsp. zooepidemicus MGCS10565 copper homeostasis protein CutC-like YP_002122890.1 523347 R 552526 CDS YP_002122891.1 195977647 6761245 524187..524741 1 NC_011134.1 similar to gb|AAN18301.1| acetyltransferase [Streptococcus equi]; GNAT family acetyltransferase 524741 6761245 Sez_0506 Streptococcus equi subsp. zooepidemicus MGCS10565 GNAT family acetyltransferase YP_002122891.1 524187 D 552526 CDS YP_002122892.1 195977648 6761246 525216..526346 1 NC_011134.1 similar to ref|YP_596508.1| transposase [Streptococcus pyogenes MGAS9429]; transposase IS1548-like 526346 6761246 Sez_0507 Streptococcus equi subsp. zooepidemicus MGCS10565 transposase IS1548-like YP_002122892.1 525216 D 552526 CDS YP_002122893.1 195977649 6761229 526511..526987 1 NC_011134.1 similar to ref|NP_721985.1| methylated-DNA--protein-cysteine S-methyltransferase [Streptococcus mutans UA159]; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction:the enzyme is irreversibly inactivated.; methylated-DNA--protein-cysteine methyltransferase 526987 6761229 Sez_0508 Streptococcus equi subsp. zooepidemicus MGCS10565 methylated-DNA--protein-cysteine methyltransferase YP_002122893.1 526511 D 552526 CDS YP_002122894.1 195977650 6761228 526991..527344 1 NC_011134.1 similar to ref|YP_059682.1| Arsenate reductase family protein [Streptococcus pyogenes MGAS10394]; arsenate reductase 527344 6761228 Sez_0509 Streptococcus equi subsp. zooepidemicus MGCS10565 arsenate reductase YP_002122894.1 526991 D 552526 CDS YP_002122895.1 195977651 6761209 complement(527420..528247) 1 NC_011134.1 similar to ref|YP_596074.1| exodeoxyribonuclease III [Streptococcus pyogenes MGAS9429]; In addition to 3' to 5' exonuclease and 3'-phosphatase activities, exoA was shown to make single-strand breaks at apurinic sites in DNA.; exodeoxyribonuclease ExoA 528247 exoA 6761209 exoA Streptococcus equi subsp. zooepidemicus MGCS10565 exodeoxyribonuclease ExoA YP_002122895.1 527420 R 552526 CDS YP_002122896.1 195977652 6761224 528600..533504 1 NC_011134.1 similar to ref|YP_596076.1| interleukin-8 protease [Streptococcus pyogenes MGAS9429]; This virulence factor of S.pyogenes specifically cleaves IL-8.; serine endopeptidase ScpC, lactocepin, interleukin-8 protease 533504 scpC 6761224 scpC Streptococcus equi subsp. zooepidemicus MGCS10565 serine endopeptidase ScpC, lactocepin, interleukin-8 protease YP_002122896.1 528600 D 552526 CDS YP_002122897.1 195977653 6761207 533679..535358 1 NC_011134.1 similar to ref|ZP_00874690.1| conserved hypothetical protein [Streptococcus suis 89/1591]; cell shape-determining protein 535358 6761207 Sez_0512 Streptococcus equi subsp. zooepidemicus MGCS10565 cell shape-determining protein YP_002122897.1 533679 D 552526 CDS YP_002122898.1 195977654 6761221 535893..537077 1 NC_011134.1 similar to emb|CAJ66811.1| cell-wall anchored surface adhesin [Streptococcus agalactiae]; Unknown, possible cell surface adhesin/albumin-binding protein.; cell surface protein 537077 6761221 Sez_0513 Streptococcus equi subsp. zooepidemicus MGCS10565 cell surface protein YP_002122898.1 535893 D 552526 CDS YP_002122899.1 195977655 6761210 537258..537500 1 NC_011134.1 similar to ref|ZP_02010661.1| Heparinase II/III family protein [Opitutaceae bacterium TAV2]; hypothetical protein 537500 6761210 Sez_0514 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002122899.1 537258 D 552526 CDS YP_002122900.1 195977656 6761214 537517..538161 1 NC_011134.1 similar to ref|YP_596079.1| hypothetical membrane spanning protein [Streptococcus pyogenes MGAS9429]; hypothetical protein 538161 6761214 Sez_0515 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002122900.1 537517 D 552526 CDS YP_002122901.1 195977657 6761200 538365..540383 1 NC_011134.1 methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content; methionyl-tRNA synthetase 540383 metG 6761200 metG Streptococcus equi subsp. zooepidemicus MGCS10565 methionyl-tRNA synthetase YP_002122901.1 538365 D 552526 CDS YP_002122902.1 195977658 6761199 540941..541834 1 NC_011134.1 similar to ref|YP_001451328.1| transcription activator plcR [Streptococcus gordonii str. Challis substr. CH1]; transcriptional regulator PlcR 541834 plcR 6761199 plcR Streptococcus equi subsp. zooepidemicus MGCS10565 transcriptional regulator PlcR YP_002122902.1 540941 D 552526 CDS YP_002122903.1 195977659 6761205 542187..542327 1 NC_011134.1 possible competence stimulating peptide with double glycine leader peptide and ABC transporter secretion; hypothetical protein 542327 6761205 Sez_0518 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002122903.1 542187 D 552526 CDS YP_002122904.1 195977660 6761203 542467..542598 1 NC_011134.1 possible competence stimulating peptide with double glycine leader peptide and ABC transporter secretion.; hypothetical protein 542598 6761203 Sez_0519 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002122904.1 542467 D 552526 CDS YP_002122905.1 195977661 6761204 542781..542948 1 NC_011134.1 possible competence stimulating peptide with double glycine leader peptide and ABC transporter secretion.; hypothetical protein 542948 6761204 Sez_0520 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002122905.1 542781 D 552526 CDS YP_002122906.1 195977662 6761192 543175..545328 1 NC_011134.1 similar to ref|ZP_01824165.1| competence factor transporting ATP-binding/permease ComA [Streptococcus pneumoniae SP11-BS70]; Required for induction of competence. Seems to transport the competence-stimulating peptide (CSP).; transport/processing ATP-binding protein ComA 545328 comA 6761192 comA Streptococcus equi subsp. zooepidemicus MGCS10565 transport/processing ATP-binding protein ComA YP_002122906.1 543175 D 552526 CDS YP_002122907.1 195977663 6761198 545343..546710 1 NC_011134.1 similar to ref|YP_815485.1| competence factor transport protein ComB [Streptococcus pneumoniae D39]; Required for induction of competence.; transport protein ComB 546710 comB 6761198 comB Streptococcus equi subsp. zooepidemicus MGCS10565 transport protein ComB YP_002122907.1 545343 D 552526 CDS YP_002122908.1 195977664 6761195 547291..547455 1 NC_011134.1 similar to ref|ZP_00874789.1| conserved hypothetical protein [Streptococcus suis 89/1591]; hypothetical protein 547455 6761195 Sez_0523 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002122908.1 547291 D 552526 CDS YP_002122909.1 195977665 6761196 547910..548923 1 NC_011134.1 similar to ref|YP_601843.1| ribonucleotide-diphosphate reductase subunit beta [Streptococcus pyogenes MGAS10750]; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.; ribonucleotide-diphosphate reductase subunit beta 548923 nrdF 6761196 nrdF Streptococcus equi subsp. zooepidemicus MGCS10565 ribonucleotide-diphosphate reductase subunit beta YP_002122909.1 547910 D 552526 CDS YP_002122910.1 195977666 6761193 548925..549335 1 NC_011134.1 similar to ref|YP_601844.1| ribonucleotide reductase stimulatory protein [Streptococcus pyogenes MGAS10750]; Unknown; probably involved in ribonucleotide reductase function.; ribonucleotide reduction protein NrdI 549335 nrdI 6761193 nrdI Streptococcus equi subsp. zooepidemicus MGCS10565 ribonucleotide reduction protein NrdI YP_002122910.1 548925 D 552526 CDS YP_002122911.1 195977667 6761188 549381..551555 1 NC_011134.1 Catalyzes the rate-limiting step in dNTP synthesis; ribonucleotide-diphosphate reductase subunit alpha 551555 nrdE 6761188 nrdE Streptococcus equi subsp. zooepidemicus MGCS10565 ribonucleotide-diphosphate reductase subunit alpha YP_002122911.1 549381 D 552526 CDS YP_002122912.1 195977668 6761185 complement(551523..551690) 1 NC_011134.1 similar to ref|NP_486386.1| hypothetical protein alr2346 [Nostoc sp. PCC 7120]; hypothetical protein 551690 6761185 Sez_0527 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002122912.1 551523 R 552526 CDS YP_002122913.1 195977669 6761181 552109..553452 1 NC_011134.1 similar to ref|ZP_00781600.1| branched-chain amino acid transport system II carrier protein [Streptococcus agalactiae 18RS21]; Component of the transport system for branched-chain amino acids (leucine, isoleucine and valine) Which is coupled to a proton motive force.; branched-chain amino acid transport system carrier protein BraB 553452 braB 6761181 braB Streptococcus equi subsp. zooepidemicus MGCS10565 branched-chain amino acid transport system carrier protein BraB YP_002122913.1 552109 D 552526 CDS YP_002122914.1 195977670 6761189 complement(553571..554863) 1 NC_011134.1 similar to ref|ZP_00875692.1| Transposase, IS204/IS1001/IS1096/IS1165 [Streptococcus suis 89/1591]; transposase IS1193D 554863 6761189 Sez_0529 Streptococcus equi subsp. zooepidemicus MGCS10565 transposase IS1193D YP_002122914.1 553571 R 552526 CDS YP_002122915.1 195977671 6761176 555369..555665 1 NC_011134.1 similar to ref|ZP_02093562.1| hypothetical protein PEPMIC_00313 [Peptostreptococcus micros ATCC 33270]; Virulence factor that is important for the establishment of infection in the host. pfam06013 Proteins of 100 residues with WXG. ESAT-6 is a small protein appears to be of fundamental importance in virulence and protective immunity in Mycobacterium tuberculosis. Homologues have been detected in other Gram-positive bacterial species. It may represent a novel secretion system potentially driven by the pfam01580 domains in the YukA-like proteins.; ESAT-6/Esx family secreted protein EsxA/YukE 555665 esxA 6761176 esxA Streptococcus equi subsp. zooepidemicus MGCS10565 ESAT-6/Esx family secreted protein EsxA/YukE YP_002122915.1 555369 D 552526 CDS YP_002122916.1 195977672 6761183 555785..558922 1 NC_011134.1 similar to ref|ZP_02093561.1| hypothetical protein PEPMIC_00312 [Peptostreptococcus micros ATCC 33270]; Unknown, likely involved in export of the adjacent ESAT-6 family protein.; secretion accessory protein EsaA/YueB 558922 esaA 6761183 esaA Streptococcus equi subsp. zooepidemicus MGCS10565 secretion accessory protein EsaA/YueB YP_002122916.1 555785 D 552526 CDS YP_002122917.1 195977673 6761180 558888..559412 1 NC_011134.1 similar to ref|ZP_02093560.1| hypothetical protein PEPMIC_00311 [Peptostreptococcus micros ATCC 33270]; hypothetical protein 559412 6761180 Sez_0532 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002122917.1 558888 D 552526 CDS YP_002122918.1 195977674 6761158 559695..559973 1 NC_011134.1 similar to ref|ZP_02093559.1| hypothetical protein PEPMIC_00310 [Peptostreptococcus micros ATCC 33270]; hypothetical protein 559973 6761158 Sez_0533 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002122918.1 559695 D 552526 CDS YP_002122919.1 195977675 6761179 559976..561133 1 NC_011134.1 similar to ref|ZP_02093558.1| hypothetical protein PEPMIC_00309 [Peptostreptococcus micros ATCC 33270]; Required for secretion of esxA.; secretion system component EssB/YukC 561133 essB 6761179 essB Streptococcus equi subsp. zooepidemicus MGCS10565 secretion system component EssB/YukC YP_002122919.1 559976 D 552526 CDS YP_002122920.1 195977676 6761174 561145..565521 1 NC_011134.1 similar to ref|ZP_02093557.1| hypothetical protein PEPMIC_00308 [Peptostreptococcus micros ATCC 33270]; Possibly involved in export of the adjacent ESAT-6 family protein.; DNA translocase FtsK 565521 essC 6761174 essC Streptococcus equi subsp. zooepidemicus MGCS10565 DNA translocase FtsK YP_002122920.1 561145 D 552526 CDS YP_002122921.1 195977677 6761066 565534..565863 1 NC_011134.1 similar to ref|ZP_02093556.1| hypothetical protein PEPMIC_00307 [Peptostreptococcus micros ATCC 33270]; hypothetical protein 565863 6761066 Sez_0536 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002122921.1 565534 D 552526 CDS YP_002122922.1 195977678 6761170 565867..566301 1 NC_011134.1 similar to ref|ZP_02093555.1| hypothetical protein PEPMIC_00306 [Peptostreptococcus micros ATCC 33270]; hypothetical protein 566301 6761170 Sez_0537 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002122922.1 565867 D 552526 CDS YP_002122923.1 195977679 6761169 566303..566587 1 NC_011134.1 similar to ref|ZP_02093554.1| hypothetical protein PEPMIC_00305 [Peptostreptococcus micros ATCC 33270]; hypothetical protein 566587 6761169 Sez_0538 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002122923.1 566303 D 552526 CDS YP_002122924.1 195977680 6761168 566699..568519 1 NC_011134.1 similar to ref|ZP_02093553.1| hypothetical protein PEPMIC_00304 [Peptostreptococcus micros ATCC 33270]; hypothetical protein 568519 6761168 Sez_0539 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002122924.1 566699 D 552526 CDS YP_002122925.1 195977681 6761166 568501..568890 1 NC_011134.1 similar to ref|YP_001450781.1| Gene info hypothetical protein SGO_1502 [Streptococcus gordonii str. Challis substr. CH1]; hypothetical protein 568890 6761166 Sez_0540 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002122925.1 568501 D 552526 CDS YP_002122926.1 195977682 6761163 568915..569322 1 NC_011134.1 similar to ref|ZP_00230000.1| hypothetical protein LMOh7858_0095 [Listeria monocytogenes str. 4b H7858]; hypothetical protein 569322 6761163 Sez_0541 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002122926.1 568915 D 552526 CDS YP_002122927.1 195977683 6761146 569392..570507 1 NC_011134.1 similar to ref|ZP_02093564.1| hypothetical protein PEPMIC_00315 [Peptostreptococcus micros ATCC 33270]; hypothetical protein 570507 6761146 Sez_0542 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002122927.1 569392 D 552526 CDS YP_002122928.1 195977684 6761149 570504..570803 1 NC_011134.1 similar to ref|YP_983629.1| Gene info UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase [Polaromonas naphthalenivorans CJ2]; hypothetical protein 570803 6761149 Sez_0543 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002122928.1 570504 D 552526 CDS YP_002122929.1 195977685 6761162 570968..571297 1 NC_011134.1 similar to ref|NP_928651.1| hypothetical protein plu1347 [Photorhabdus luminescens subsp. laumondii TTO1]; hypothetical protein 571297 6761162 Sez_0544 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002122929.1 570968 D 552526 CDS YP_002122930.1 195977686 6761136 571313..571579 1 NC_011134.1 similar to ref|XP_001092846.1| PREDICTED: immunoglobulin lambda variable 7-43 [Macaca mulatta]; hypothetical protein 571579 6761136 Sez_0545 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002122930.1 571313 D 552526 CDS YP_002122931.1 195977687 6761155 571656..572027 1 NC_011134.1 similar to ref|ZP_01090397.1| hypothetical protein DSM3645_11836 [Blastopirellula marina DSM 3645]; hypothetical protein 572027 6761155 Sez_0546 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002122931.1 571656 D 552526 CDS YP_002122932.1 195977688 6761156 572028..572621 1 NC_011134.1 similar to ref|YP_001093031.1| Transketolase, central region [Shewanella loihica PV-4]; hypothetical protein 572621 6761156 Sez_0547 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002122932.1 572028 D 552526 CDS YP_002122933.1 195977689 6761135 573087..575540 1 NC_011134.1 similar to ref|NP_722087.1| hypothetical protein SMU.1764c [Streptococcus mutans UA159]; CRISPR mediated immunity, TIGRFAM TIGR01596.; CRISPR-Associated Helicase Cas3 Core 575540 cas3 6761135 cas3 Streptococcus equi subsp. zooepidemicus MGCS10565 CRISPR-Associated Helicase Cas3 Core YP_002122933.1 573087 D 552526 CDS YP_002122934.1 195977690 6761153 575781..576500 1 NC_011134.1 similar to ref|NP_722086.1| hypothetical protein SMU.1763c [Streptococcus mutans UA159]; CRISPR mediated immunity, TIGRFAM TIGR01876.; CRISPR-associated protein Cas5 576500 cas5 6761153 cas5 Streptococcus equi subsp. zooepidemicus MGCS10565 CRISPR-associated protein Cas5 YP_002122934.1 575781 D 552526 CDS YP_002122935.1 195977691 6761150 576500..578383 1 NC_011134.1 similar to ref|YP_598979.1| hypothetical protein MGAS10270_Spy1370 [Streptococcus pyogenes MGAS10270]; CRISPR mediated immunity, TIGRFAM TIGR01863.; Csd1 family CRISPR-associated protein 578383 csd1 6761150 csd1 Streptococcus equi subsp. zooepidemicus MGCS10565 Csd1 family CRISPR-associated protein YP_002122935.1 576500 D 552526 CDS YP_002122936.1 195977692 6761147 578384..579232 1 NC_011134.1 similar to ref|YP_280757.1| hypothetical cytosolic protein [Streptococcus pyogenes MGAS6180]; CRISPR mediated immunity, TIGRFAM TIGR02589.; Csd2 family CRISPR-associated protein 579232 csd2 6761147 csd2 Streptococcus equi subsp. zooepidemicus MGCS10565 Csd2 family CRISPR-associated protein YP_002122936.1 578384 D 552526 CDS YP_002122937.1 195977693 6761143 579234..579905 1 NC_011134.1 similar to ref|NP_269629.1| hypothetical protein SPy_1563 [Streptococcus pyogenes M1 GAS]; CRISPR mediated immunity, TIGRFAM TIGR00372.; CRISPR-associated RecB family exonuclease Cas4b 579905 cas4 6761143 cas4 Streptococcus equi subsp. zooepidemicus MGCS10565 CRISPR-associated RecB family exonuclease Cas4b YP_002122937.1 579234 D 552526 CDS YP_002122938.1 195977694 6761138 579902..580927 1 NC_011134.1 similar to ref|YP_597011.1| hypothetical protein MGAS9429_Spy1280 [Streptococcus pyogenes MGAS9429]; CRISPR mediated immunity, TIGRFAM TIGR00287.; CRISPR-associated protein Cas1 580927 cas1 6761138 cas1 Streptococcus equi subsp. zooepidemicus MGCS10565 CRISPR-associated protein Cas1 YP_002122938.1 579902 D 552526 CDS YP_002122939.1 195977695 6761137 580938..581231 1 NC_011134.1 similar to ref|NP_722078.1| hypothetical protein SMU.1753c [Streptococcus mutans UA159]; CRISPR mediated immunity, TIGRFAM TIGR01573.; CRISPR-associated protein Cas2 581231 cas2 6761137 cas2 Streptococcus equi subsp. zooepidemicus MGCS10565 CRISPR-associated protein Cas2 YP_002122939.1 580938 D 552526 CDS YP_002122940.1 195977696 6761141 584155..584865 1 NC_011134.1 similar to ref|YP_001128141.1| cytochrome c-type biogenesis protein [Streptococcus pyogenes str. Manfredo]; Could be involved in cytochrome c synthesis.; cytochrome c-type biogenesis protein CcdA (DsbD analog) 584865 dsbD 6761141 dsbD Streptococcus equi subsp. zooepidemicus MGCS10565 cytochrome c-type biogenesis protein CcdA (DsbD analog) YP_002122940.1 584155 D 552526 CDS YP_002122941.1 195977697 6761124 584858..585529 1 NC_011134.1 similar to gb|AAN18289.1| lipoprotein [Streptococcus equi]; Involved in disulfide bond formation; related to ResA; thiol:disulfide oxidoreductase 585529 dsbE 6761124 dsbE Streptococcus equi subsp. zooepidemicus MGCS10565 thiol:disulfide oxidoreductase YP_002122941.1 584858 D 552526 CDS YP_002122942.1 195977698 6761102 585547..586659 1 NC_011134.1 similar to ref|NP_269624.1| bifunctional methionine sulfoxide reductase A/B protein [Streptococcus pyogenes M1 GAS]; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.; peptide methionine sulfoxide reductase 586659 msrAB 6761102 msrAB Streptococcus equi subsp. zooepidemicus MGCS10565 peptide methionine sulfoxide reductase YP_002122942.1 585547 D 552526 CDS YP_002122943.1 195977699 6761050 586832..587668 1 NC_011134.1 similar to gb|AAN18291.1| two-component response regulator [Streptococcus equi]; two-component response regulator YesN-like 587668 yesN 6761050 yesN Streptococcus equi subsp. zooepidemicus MGCS10565 two-component response regulator YesN-like YP_002122943.1 586832 D 552526 CDS YP_002122944.1 195977700 6761116 587665..589383 1 NC_011134.1 similar to ref|YP_282643.1| two-component sensor kinase [Streptococcus pyogenes MGAS5005]; two-component sensor kinase YesM-like 589383 yesM 6761116 yesM Streptococcus equi subsp. zooepidemicus MGCS10565 two-component sensor kinase YesM-like YP_002122944.1 587665 D 552526 CDS YP_002122945.1 195977701 6761131 589423..590511 1 NC_011134.1 similar to ref|YP_602880.1| hypothetical cytosolic protein [Streptococcus pyogenes MGAS10750]; hypothetical protein 590511 6761131 Sez_0563 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002122945.1 589423 D 552526 CDS YP_002122946.1 195977702 6761111 590526..591230 1 NC_011134.1 similar to ref|YP_598902.1| hypothetical protein MGAS10270_Spy1293 [Streptococcus pyogenes MGAS10270]; hypothetical protein 591230 6761111 Sez_0564 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002122946.1 590526 D 552526 CDS YP_002122947.1 195977703 6761127 591465..591977 1 NC_011134.1 similar to ref|YP_619784.1| hypothetical protein Ldb2202 [Lactobacillus delbrueckii subsp. bulgaricus ATCC 11842]; hypothetical protein 591977 6761127 Sez_0565 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002122947.1 591465 D 552526 CDS YP_002122948.1 195977704 6761120 complement(592488..592961) 1 NC_011134.1 similar to ref|YP_598901.1| Arginine repressor, argR [Streptococcus pyogenes MGAS10270]; Regulates arginine biosynthesis genes.; arginine repressor ArgR 592961 argR 6761120 argR Streptococcus equi subsp. zooepidemicus MGCS10565 arginine repressor ArgR YP_002122948.1 592488 R 552526 CDS YP_002122949.1 195977705 6761096 593102..593782 1 NC_011134.1 similar to dbj|BAE46419.1| CRP/FNR transcriptional regulator [Streptococcus equi subsp. zooepidemicus]; ArcR family transcriptional regulator 593782 arcR 6761096 arcR Streptococcus equi subsp. zooepidemicus MGCS10565 ArcR family transcriptional regulator YP_002122949.1 593102 D 552526 CDS YP_002122950.1 195977706 6761100 594051..595286 1 NC_011134.1 catalyzes the degradation of arginine to citruline and ammonia; arginine deiminase 595286 arcA 6761100 arcA Streptococcus equi subsp. zooepidemicus MGCS10565 arginine deiminase YP_002122950.1 594051 D 552526 CDS YP_002122951.1 195977707 6761113 595296..595727 1 NC_011134.1 similar to dbj|BAE46421.1| GNAT family acetyltransferase [Streptococcus equi subsp. zooepidemicus]; GNAT family acetyltransferase 595727 6761113 Sez_0569 Streptococcus equi subsp. zooepidemicus MGCS10565 GNAT family acetyltransferase YP_002122951.1 595296 D 552526 CDS YP_002122952.1 195977708 6761107 595742..596755 1 NC_011134.1 catalyzes the formation of ornithine and carbamylphosphate from citrulline in the arginine catabolic pathway; ornithine carbamoyltransferase 596755 arcB 6761107 arcB Streptococcus equi subsp. zooepidemicus MGCS10565 ornithine carbamoyltransferase YP_002122952.1 595742 D 552526 CDS YP_002122953.1 195977709 6761106 596917..598410 1 NC_011134.1 similar to dbj|BAE46423.1| arginine/ornithine antiporter [Streptococcus equi subsp. zooepidemicus]; arginine/ornithine antiporter ArcD 598410 arcD 6761106 arcD Streptococcus equi subsp. zooepidemicus MGCS10565 arginine/ornithine antiporter ArcD YP_002122953.1 596917 D 552526 CDS YP_002122954.1 195977710 6761074 598427..599758 1 NC_011134.1 similar to ref|ZP_00365692.1| COG0624: Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases [Streptococcus pyogenes M49 591]; catalyzing the hydrolysis of N2-acetyl-l-ornithine to l-ornithine and acetate.; hypothetical protein 599758 6761074 Sez_0572 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002122954.1 598427 D 552526 CDS YP_002122955.1 195977711 6761110 599776..600726 1 NC_011134.1 catalyzes the reversible synthesis of carbamate and ATP from carbamoyl phosphate and ADP; carbamate kinase 600726 arcC 6761110 arcC Streptococcus equi subsp. zooepidemicus MGCS10565 carbamate kinase YP_002122955.1 599776 D 552526 CDS YP_002122956.1 195977712 6761101 600945..601937 1 NC_011134.1 catalyzes the formation of asparagine from aspartate and ammonia; asparagine synthetase AsnA 601937 asnA 6761101 asnA Streptococcus equi subsp. zooepidemicus MGCS10565 asparagine synthetase AsnA YP_002122956.1 600945 D 552526 CDS YP_002122957.1 195977713 6761086 602106..602645 1 NC_011134.1 similar to ref|ZP_00365420.1| COG0742: N6-adenine-specific methylase [Streptococcus pyogenes M49 591]; Methyltransferase; methylase 602645 6761086 Sez_0575 Streptococcus equi subsp. zooepidemicus MGCS10565 methylase YP_002122957.1 602106 D 552526 CDS YP_002122958.1 195977714 6761098 602635..603135 1 NC_011134.1 Catalyzes the conversion of ATP and pantetheine 4'-phosphate to diphosphate and 3'-dephospho-coA; phosphopantetheine adenylyltransferase 603135 coaD 6761098 coaD Streptococcus equi subsp. zooepidemicus MGCS10565 phosphopantetheine adenylyltransferase YP_002122958.1 602635 D 552526 CDS YP_002122959.1 195977715 6761064 603113..604150 1 NC_011134.1 similar to ref|YP_060605.1| ATP-dependent protease La [Streptococcus pyogenes MGAS10394]; Lon-like protease with PDZ domain 604150 6761064 Sez_0577 Streptococcus equi subsp. zooepidemicus MGCS10565 Lon-like protease with PDZ domain YP_002122959.1 603113 D 552526 CDS YP_002122960.1 195977716 6761084 604726..605370 1 NC_011134.1 similar to ref|YP_060601.1| Transcriptional regulator [Streptococcus pyogenes MGAS10394]; transcriptional regulator 605370 6761084 Sez_0578 Streptococcus equi subsp. zooepidemicus MGCS10565 transcriptional regulator YP_002122960.1 604726 D 552526 CDS YP_002122961.1 195977717 6761088 605374..606456 1 NC_011134.1 23S rRNA m2A2503 methyltransferase; methylates the C2 position of the A2530 nucleotide in 23S rRNA; may be involved in antibiotic resistance; ribosomal RNA large subunit methyltransferase N 606456 6761088 Sez_0579 Streptococcus equi subsp. zooepidemicus MGCS10565 ribosomal RNA large subunit methyltransferase N YP_002122961.1 605374 D 552526 CDS YP_002122962.1 195977718 6761081 607020..607925 1 NC_011134.1 similar to ref|YP_001451006.1| ABC transporter ATP-binding protein SP2003 [Streptococcus gordonii str. Challis substr. CH1]; multi drug transpot ATP-binding protein 607925 6761081 Sez_0580 Streptococcus equi subsp. zooepidemicus MGCS10565 multi drug transpot ATP-binding protein YP_002122962.1 607020 D 552526 CDS YP_002122963.1 195977719 6761076 607929..608654 1 NC_011134.1 similar to ref|NP_687344.1| ABC transporter, permease, [Streptococcus agalactiae 2603V/R]; ABC transporter permease 608654 6761076 Sez_0581 Streptococcus equi subsp. zooepidemicus MGCS10565 ABC transporter permease YP_002122963.1 607929 D 552526 CDS YP_002122964.1 195977720 6761092 608654..609766 1 NC_011134.1 similar to ref|YP_139771.1| sensor histidine kinase (homolog to HK11 Spn) [Streptococcus thermophilus LMG 18311]; TCS sensor histidine kinase 609766 6761092 Sez_0582 Streptococcus equi subsp. zooepidemicus MGCS10565 TCS sensor histidine kinase YP_002122964.1 608654 D 552526 CDS YP_002122965.1 195977721 6761068 609747..610343 1 NC_011134.1 similar to ref|ZP_00784861.1| response regulator [Streptococcus agalactiae COH1]; TCS response regulator 610343 6761068 Sez_0583 Streptococcus equi subsp. zooepidemicus MGCS10565 TCS response regulator YP_002122965.1 609747 D 552526 CDS YP_002122966.1 195977722 6761078 complement(610404..611045) 1 NC_011134.1 similar to ref|YP_598885.1| Type 4 prepilin peptidase pilD [Streptococcus pyogenes MGAS10270]; type IV prepilin peptidase PilD / late competence protein ComC processing protease 611045 pilD 6761078 pilD Streptococcus equi subsp. zooepidemicus MGCS10565 type IV prepilin peptidase PilD / late competence protein ComC processing protease YP_002122966.1 610404 R 552526 CDS YP_002122967.1 195977723 6761077 611253..611783 1 NC_011134.1 similar to ref|NP_269604.1| peroxide resistance protein [Streptococcus pyogenes M1 GAS]; Is involved in iron storage. May also be involved in the metabolic response to stress conditions.; DNA binding protein starved cells-like peroxide resistance protein Dpr 611783 dpr 6761077 dpr Streptococcus equi subsp. zooepidemicus MGCS10565 DNA binding protein starved cells-like peroxide resistance protein Dpr YP_002122967.1 611253 D 552526 CDS YP_002122968.1 195977724 6761048 612153..612386 1 NC_011134.1 similar to ref|NP_664985.1| hypothetical protein SpyM3_1181 [Streptococcus pyogenes MGAS315]; hypothetical protein 612386 6761048 Sez_0586 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002122968.1 612153 D 552526 CDS YP_002122969.1 195977725 6761061 612361..613332 1 NC_011134.1 similar to ref|NP_607614.1| glucose kinase [Streptococcus pyogenes MGAS8232]; Catalysis of the reaction: ATP + D-glucose = ADP + D-glucose 6-phosphate.; glucokinase 613332 glcK 6761061 glcK Streptococcus equi subsp. zooepidemicus MGCS10565 glucokinase YP_002122969.1 612361 D 552526 CDS YP_002122970.1 195977726 6761041 613357..613722 1 NC_011134.1 similar to ref|YP_060595.1| Rhodanese-related sulfurtransferase [Streptococcus pyogenes MGAS10394]; rhodanese-Like domain-containing protein 613722 6761041 Sez_0588 Streptococcus equi subsp. zooepidemicus MGCS10565 rhodanese-Like domain-containing protein YP_002122970.1 613357 D 552526 CDS YP_002122971.1 195977727 6761042 614100..615959 1 NC_011134.1 similar to ref|NP_269600.1| GTP-binding protein TypA/BipA (tyrosine phosphorylated protein A) [Streptococcus pyogenes M1 GAS]; Unknown; probably interacts with the ribosomes in a GTP dependent manner.; GTP-binding protein TypA 615959 typA 6761042 typA Streptococcus equi subsp. zooepidemicus MGCS10565 GTP-binding protein TypA YP_002122971.1 614100 D 552526 CDS YP_002122972.1 195977728 6761062 616044..616292 1 NC_011134.1 similar to ref|NP_607611.1| hypothetical protein spyM18_1543 [Streptococcus pyogenes MGAS8232]; hypothetical protein 616292 6761062 Sez_0590 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002122972.1 616044 D 552526 CDS YP_002122973.1 195977729 6761058 616445..617803 1 NC_011134.1 UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase 617803 murD 6761058 murD Streptococcus equi subsp. zooepidemicus MGCS10565 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase YP_002122973.1 616445 D 552526 CDS YP_002122974.1 195977730 6761056 617803..618885 1 NC_011134.1 UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; involved in cell wall formation; inner membrane-associated; last step of peptidoglycan synthesis; UDP diphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase 618885 murG 6761056 murG Streptococcus equi subsp. zooepidemicus MGCS10565 UDP diphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase YP_002122974.1 617803 D 552526 CDS YP_002122975.1 195977731 6761059 618886..620076 1 NC_011134.1 similar to ref|NP_269596.1| cell division protein [Streptococcus pyogenes M1 GAS]; Required for the initiation of cell division. Exact function not known.; cell division protein FtsQ 620076 ftsQ 6761059 ftsQ Streptococcus equi subsp. zooepidemicus MGCS10565 cell division protein FtsQ YP_002122975.1 618886 D 552526 CDS YP_002122976.1 195977732 6761057 620288..621652 1 NC_011134.1 similar to ref|YP_060589.1| Cell division protein ftsA [Streptococcus pyogenes MGAS10394]; This protein may be involved in anomalous filament growth. May be a component of the septum. It may interact with ftsZ (By similarity).; cell division protein FtsA 621652 ftsA 6761057 ftsA Streptococcus equi subsp. zooepidemicus MGCS10565 cell division protein FtsA YP_002122976.1 620288 D 552526 CDS YP_002122977.1 195977733 6761051 623005..623679 1 NC_011134.1 similar to ref|YP_280652.1| pyridoxal-5'-phosphate family protein [Streptococcus pyogenes MGAS6180]; pyridoxaL 5'-phosphate dependent enzyme class III family 623679 6761051 Sez_0597 Streptococcus equi subsp. zooepidemicus MGCS10565 pyridoxaL 5'-phosphate dependent enzyme class III family YP_002122977.1 623005 D 552526 CDS YP_002122978.1 195977734 6761047 623680..624354 1 NC_011134.1 similar to ref|ZP_00366475.1| COG1799: Uncharacterized protein conserved in bacteria [Streptococcus pyogenes M49 591]; hypothetical protein 624354 6761047 Sez_0598 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002122978.1 623680 D 552526 CDS YP_002122979.1 195977735 6761044 624410..624616 1 NC_011134.1 similar to ref|ZP_00366474.1| COG0762: Predicted integral membrane protein [Streptococcus pyogenes M49 591]; hypothetical protein 624616 6761044 Sez_0599 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002122979.1 624410 D 552526 CDS YP_002122980.1 195977736 6761029 624613..625224 1 NC_011134.1 similar to ref|YP_060584.1| RNA binding protein [Streptococcus pyogenes MGAS10394]; Unknown, The S4 domain is a small domain consisting of 60-65 amino acid residues that was detected in the bacterial ribosomal protein S4, eukaryotic ribosomal S9, two families of pseudouridine synthases, a novel family of predicted RNA methylases, a yeast protein containing a pseudouridine synthetase and a deaminase domain, bacterial tyrosyl-tRNA synthetases, and a number of uncharacterized, small proteins that may be involved in translation regulation. The S4 domain probably mediates binding to RNA.; S4 domain-containing protein 625224 6761029 Sez_0600 Streptococcus equi subsp. zooepidemicus MGCS10565 S4 domain-containing protein YP_002122980.1 624613 D 552526 CDS YP_002122981.1 195977737 6761037 625416..626171 1 NC_011134.1 similar to ref|YP_280648.1| cell division initiation protein DivIVA [Streptococcus pyogenes MGAS6180]; cell division initiation protein DivIVA 626171 divIVA 6761037 divIVA Streptococcus equi subsp. zooepidemicus MGCS10565 cell division initiation protein DivIVA YP_002122981.1 625416 D 552526 CDS YP_002122982.1 195977738 6761036 626443..629241 1 NC_011134.1 IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase family; some organisms carry two different copies of this enzyme; isoleucyl-tRNA synthetase 629241 ileS 6761036 ileS Streptococcus equi subsp. zooepidemicus MGCS10565 isoleucyl-tRNA synthetase YP_002122982.1 626443 D 552526 CDS YP_002122983.1 195977739 6761035 complement(629710..630012) 1 NC_011134.1 similar to ref|NP_607599.1| hypothetical protein spyM18_1529 [Streptococcus pyogenes MGAS8232]; hypothetical protein 630012 6761035 Sez_0603 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002122983.1 629710 R 552526 CDS YP_002122984.1 195977740 6760994 complement(630074..630520) 1 NC_011134.1 similar to ref|YP_280645.1| mutator protein (7,8-dihydro-8-oxoguanine-triphosphatase) [Streptococcus pyogenes MGAS6180]; Specific for pyrimidine substrates. Acts on 5-methyl- dCTP, CTP and dCTP in decreasing order.; MutT/nudix family protein 630520 mutT 6760994 mutT Streptococcus equi subsp. zooepidemicus MGCS10565 MutT/nudix family protein YP_002122984.1 630074 R 552526 CDS YP_002122985.1 195977741 6761032 complement(630667..632919) 1 NC_011134.1 similar to ref|YP_596966.1| ATP-dependent endopeptidase clp ATP-binding subunit [Streptococcus pyogenes MGAS9429]; Could be necessary for degrading proteins generated by certain types of stress.; ATP-dependent Clp protease ATP-binding subunit ClpE 632919 clpE 6761032 clpE Streptococcus equi subsp. zooepidemicus MGCS10565 ATP-dependent Clp protease ATP-binding subunit ClpE YP_002122985.1 630667 R 552526 CDS YP_002122986.1 195977742 6761020 633202..633432 1 NC_011134.1 similar to ref|NP_269584.1| hypothetical protein SPy_1508 [Streptococcus pyogenes M1 GAS]; hypothetical protein 633432 6761020 Sez_0606 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002122986.1 633202 D 552526 CDS YP_002122987.1 195977743 6761028 633440..633568 1 NC_011134.1 similar to ref|NP_730978.1| sec23 CG1250-PA, isoform A [Drosophila melanogaster]; hypothetical protein 633568 6761028 Sez_0607 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002122987.1 633440 D 552526 CDS YP_002122988.1 195977744 6761026 complement(633877..635202) 1 NC_011134.1 similar to gb|ABA41499.1| collagen-like protein I [Streptococcus equi subsp. equi]; Possible adhesin, has a collagen-structural-motif domain composed of 95 Gly-Xaa-Yaa repeats.; hypothetical protein 635202 sclZ.7 6761026 sclZ.7 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002122988.1 633877 R 552526 CDS YP_002122989.1 195977745 6761001 635548..636027 1 NC_011134.1 similar to ref|YP_280642.1| arginine transport system permease [Streptococcus pyogenes MGAS6180]; Probably part of a binding-protein-dependent transport system for an amino acid. Probably responsible for the translocation of the substrate across the membrane.; glutamine ABC transporter permease 636027 6761001 Sez_0609 Streptococcus equi subsp. zooepidemicus MGCS10565 glutamine ABC transporter permease YP_002122989.1 635548 D 552526 CDS YP_002122990.1 195977746 6761022 636077..636232 1 NC_011134.1 similar to ref|NP_607595.1| amino acid ABC transporter (permease) [Streptococcus pyogenes MGAS8232]; Part Of The Binding-Protein-Dependent Transport System For Glutamine; Probably Responsible For The Translocation Of The Substrate Across The Membrane.; glutamine amino acid ABC transporter GlnP 636232 glnP 6761022 glnP Streptococcus equi subsp. zooepidemicus MGCS10565 glutamine amino acid ABC transporter GlnP YP_002122990.1 636077 D 552526 CDS YP_002122991.1 195977747 6761023 636234..636971 1 NC_011134.1 similar to ref|NP_721003.1| amino acid ABC transporter, ATP-binding protein [Streptococcus mutans UA159]; Probably part of a binding-protein-dependent transport system for an amino acid. Probably responsible for energy coupling to the transport system.; glutamine amino-acid ABC transporter ATP-binding protein 636971 6761023 Sez_0611 Streptococcus equi subsp. zooepidemicus MGCS10565 glutamine amino-acid ABC transporter ATP-binding protein YP_002122991.1 636234 D 552526 CDS YP_002122992.1 195977748 6761021 637097..637222 1 NC_011134.1 hypothetical protein 637222 6761021 Sez_0612 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002122992.1 637097 D 552526 CDS YP_002122993.1 195977749 6761019 637418..639112 1 NC_011134.1 similar to ref|ZP_00790189.1| phosphoglucomutase/phosphomannomutase family protein [Streptococcus agalactiae 515]; May be involved in the production of an extracellular matrix that lends structure to the pellicle of biofilms. Through its possible activity of phosphoexomutase, it may promote the synthesis of nucleotide sugars, which are incorporated into exopolysaccharides of the extracelllular matrix of B.subtilis communities.; phosphomannomutase 639112 6761019 Sez_0613 Streptococcus equi subsp. zooepidemicus MGCS10565 phosphomannomutase YP_002122993.1 637418 D 552526 CDS YP_002122994.1 195977750 6761018 639224..640078 1 NC_011134.1 catalyzes the formation of 5,10-methenyltetrahydrofolate from 5,10-methylenetetrahydrofolate and subsequent formation of 10-formyltetrahydrofolate from 5,10-methenyltetrahydrofolate; bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase 640078 folD 6761018 folD Streptococcus equi subsp. zooepidemicus MGCS10565 bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase YP_002122994.1 639224 D 552526 CDS YP_002122995.1 195977751 6761017 640075..640929 1 NC_011134.1 similar to ref|YP_139133.1| hypothetical protein stu0612 [Streptococcus thermophilus LMG 18311]; sugar kinase 640929 6761017 Sez_0615 Streptococcus equi subsp. zooepidemicus MGCS10565 sugar kinase YP_002122995.1 640075 D 552526 CDS YP_002122996.1 195977752 6761015 640926..641051 1 NC_011134.1 hypothetical protein 641051 6761015 Sez_0616 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002122996.1 640926 D 552526 CDS YP_002122997.1 195977753 6761016 641213..642553 1 NC_011134.1 bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides; exodeoxyribonuclease VII large subunit 642553 xseA 6761016 xseA Streptococcus equi subsp. zooepidemicus MGCS10565 exodeoxyribonuclease VII large subunit YP_002122997.1 641213 D 552526 CDS YP_002122998.1 195977754 6761014 642531..642746 1 NC_011134.1 catalyzes the bidirectional exonucleolytic cleavage of DNA; exodeoxyribonuclease VII small subunit 642746 xseB 6761014 xseB Streptococcus equi subsp. zooepidemicus MGCS10565 exodeoxyribonuclease VII small subunit YP_002122998.1 642531 D 552526 CDS YP_002122999.1 195977755 6761007 642746..643615 1 NC_011134.1 similar to ref|NP_607588.1| geranyltranstransferase [Streptococcus pyogenes MGAS8232]; geranyltranstransferase 643615 lepA 6761007 lepA Streptococcus equi subsp. zooepidemicus MGCS10565 geranyltranstransferase YP_002122999.1 642746 D 552526 CDS YP_002123000.1 195977756 6761012 643608..644435 1 NC_011134.1 similar to ref|NP_664957.1| hemolysin [Streptococcus pyogenes MGAS315]; hemolysin A 644435 6761012 Sez_0620 Streptococcus equi subsp. zooepidemicus MGCS10565 hemolysin A YP_002123000.1 643608 D 552526 CDS YP_002123001.1 195977757 6761013 644458..644892 1 NC_011134.1 similar to ref|YP_598854.1| Arginine repressor, argR [Streptococcus pyogenes MGAS10270]; Regulates arginine biosynthesis genes.; arginine repressor ArgR 644892 argR 6761013 argR Streptococcus equi subsp. zooepidemicus MGCS10565 arginine repressor ArgR YP_002123001.1 644458 D 552526 CDS YP_002123002.1 195977758 6761004 644871..646571 1 NC_011134.1 similar to ref|YP_600842.1| DNA repair protein recN [Streptococcus pyogenes MGAS2096]; May be involved in recombinational repair of damaged DNA.; DNA repair protein RecN 646571 recN 6761004 recN Streptococcus equi subsp. zooepidemicus MGCS10565 DNA repair protein RecN YP_002123002.1 644871 D 552526 CDS YP_002123003.1 195977759 6761011 646791..647663 1 NC_011134.1 similar to ref|YP_602827.1| hypothetical protein MGAS10750_Spy1333 [Streptococcus pyogenes MGAS10750]; hypothetical protein 647663 6761011 Sez_0623 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123003.1 646791 D 552526 CDS YP_002123004.1 195977760 6761010 647801..648652 1 NC_011134.1 similar to ref|YP_598851.1| Fatty acid-binding protein, DegV family [Streptococcus pyogenes MGAS10270]; DegV family protein 648652 6761010 Sez_0624 Streptococcus equi subsp. zooepidemicus MGCS10565 DegV family protein YP_002123004.1 647801 D 552526 CDS YP_002123005.1 195977761 6761009 648645..649487 1 NC_011134.1 similar to ref|YP_282588.1| lipase/acylhydrolase with GDSL-like motif [Streptococcus pyogenes MGAS5005]; lipase/acylhydrolase with GDSL-like motif 649487 6761009 Sez_0625 Streptococcus equi subsp. zooepidemicus MGCS10565 lipase/acylhydrolase with GDSL-like motif YP_002123005.1 648645 D 552526 CDS YP_002123006.1 195977762 6760999 649465..650052 1 NC_011134.1 similar to ref|YP_280628.1| hypothetical membrane associated protein [Streptococcus pyogenes MGAS6180]; hypothetical protein 650052 6760999 Sez_0626 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123006.1 649465 D 552526 CDS YP_002123007.1 195977763 6761008 650150..650425 1 NC_011134.1 similar to ref|NP_664950.1| histone-like DNA-binding protein [Streptococcus pyogenes MGAS315]; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. Seems also to act as a fortuitous virulence factor in delayed sequelae by binding to heparan sulfate-proteoglycans in the extracellular matrix of target organs and acting as a nidus for in situ immune complex formation.; DNA-binding protein HU 650425 hup 6761008 hup Streptococcus equi subsp. zooepidemicus MGCS10565 DNA-binding protein HU YP_002123007.1 650150 D 552526 CDS YP_002123008.1 195977764 6761005 complement(650483..651187) 1 NC_011134.1 similar to ref|YP_597959.1| C3 family ADP-ribosyltransferase [Streptococcus pyogenes MGAS10270]; C3 family ADP-ribosyltransferase 651187 6761005 Sez_0628 Streptococcus equi subsp. zooepidemicus MGCS10565 C3 family ADP-ribosyltransferase YP_002123008.1 650483 R 552526 CDS YP_002123009.1 195977765 6761003 complement(651498..652187) 1 NC_011134.1 similar to ref|YP_001450179.1| transporter, SP1116 [Streptococcus gordonii str. Challis substr. CH1]; macrolide ABC transporter permease 652187 6761003 Sez_0629 Streptococcus equi subsp. zooepidemicus MGCS10565 macrolide ABC transporter permease YP_002123009.1 651498 R 552526 CDS YP_002123010.1 195977766 6761000 complement(652205..652705) 1 NC_011134.1 similar to ref|NP_734700.1| hypothetical protein gbs0231 [Streptococcus agalactiae NEM316]; hypothetical protein 652705 6761000 Sez_0630 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123010.1 652205 R 552526 CDS YP_002123011.1 195977767 6760995 complement(652760..653653) 1 NC_011134.1 similar to ref|ZP_01820549.1| transcriptional regulator MutR, [Streptococcus pneumoniae SP6-BS73]; positive transcriptional regulator MutR family 653653 6760995 Sez_0631 Streptococcus equi subsp. zooepidemicus MGCS10565 positive transcriptional regulator MutR family YP_002123011.1 652760 R 552526 CDS YP_002123012.1 195977768 6761002 654024..654197 1 NC_011134.1 similar to ref|NP_664896.1| hypothetical protein SpyM3_1092 [Streptococcus pyogenes MGAS315]; hypothetical protein 654197 6761002 Sez_0632 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123012.1 654024 D 552526 CDS YP_002123013.1 195977769 6760988 complement(654245..655129) 1 NC_011134.1 catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway; subclass 1A is a dimer formed by two identical PyrD subunits each containing an FMN group; dihydroorotate dehydrogenase 1A 655129 6760988 Sez_0633 Streptococcus equi subsp. zooepidemicus MGCS10565 dihydroorotate dehydrogenase 1A YP_002123013.1 654245 R 552526 CDS YP_002123014.1 195977770 6760996 655104..655367 1 NC_011134.1 hypothetical protein 655367 6760996 Sez_0634 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123014.1 655104 D 552526 CDS YP_002123015.1 195977771 6761810 655424..656119 1 NC_011134.1 2,3-bisphosphoglycerate-dependent; catalyzes the interconversion of 2-phosphoglycerate to 3-phosphoglycerate; phosphoglyceromutase 656119 gpmA 6761810 gpmA Streptococcus equi subsp. zooepidemicus MGCS10565 phosphoglyceromutase YP_002123015.1 655424 D 552526 CDS YP_002123016.1 195977772 6761826 656207..656749 1 NC_011134.1 similar to ref|YP_280622.1| transcriptional regulator, biotin repressor family [Streptococcus pyogenes MGAS6180]; transcriptional repressor 656749 6761826 Sez_0636 Streptococcus equi subsp. zooepidemicus MGCS10565 transcriptional repressor YP_002123016.1 656207 D 552526 CDS YP_002123017.1 195977773 6761822 complement(656910..657098) 1 NC_011134.1 hypothetical protein 657098 6761822 Sez_0637 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123017.1 656910 R 552526 CDS YP_002123018.1 195977774 6761818 657144..657683 1 NC_011134.1 similar to ref|NP_269515.1| hypothetical protein SPy_1425 [Streptococcus pyogenes M1 GAS]; hypothetical protein 657683 6761818 Sez_0638 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123018.1 657144 D 552526 CDS YP_002123019.1 195977775 6761817 657794..658591 1 NC_011134.1 similar to ref|YP_596939.1| formate transporter [Streptococcus pyogenes MGAS9429]; Involved in the bidirectional transport of formate.; formate transporter 658591 6761817 Sez_0639 Streptococcus equi subsp. zooepidemicus MGCS10565 formate transporter YP_002123019.1 657794 D 552526 CDS YP_002123020.1 195977776 6761815 658703..660757 1 NC_011134.1 similar to ref|YP_820120.1| Cell division protein FtsI/penicillin-binding protein 2 [Streptococcus thermophilus LMD-9]; Cell Wall Formation; Pbp-2 Is Responsible For The Determination Of The Rod Shape Of The Cell. Its Synthesize Cross- Linked Peptidoglycan From The Lipid Intermediates.; cell division protein FtsI 660757 6761815 Sez_0640 Streptococcus equi subsp. zooepidemicus MGCS10565 cell division protein FtsI YP_002123020.1 658703 D 552526 CDS YP_002123021.1 195977777 6761794 660769..661365 1 NC_011134.1 involved in a recombinational process of DNA repair, independent of the recBC complex; recombination protein RecR 661365 recR 6761794 recR Streptococcus equi subsp. zooepidemicus MGCS10565 recombination protein RecR YP_002123021.1 660769 D 552526 CDS YP_002123022.1 195977778 6761808 661706..662752 1 NC_011134.1 D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli; D-alanyl-alanine synthetase A 662752 ddl 6761808 ddl Streptococcus equi subsp. zooepidemicus MGCS10565 D-alanyl-alanine synthetase A YP_002123022.1 661706 D 552526 CDS YP_002123023.1 195977779 6761805 663012..664376 1 NC_011134.1 similar to ref|YP_598837.1| UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [Streptococcus pyogenes MGAS10270]; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.; UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase MurF 664376 murF 6761805 murF Streptococcus equi subsp. zooepidemicus MGCS10565 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase MurF YP_002123023.1 663012 D 552526 CDS YP_002123024.1 195977780 6761803 664454..665155 1 NC_011134.1 similar to ref|NP_802044.1| hypothetical protein SPs0782 [Streptococcus pyogenes SSI-1]; hypothetical protein 665155 6761803 Sez_0644 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123024.1 664454 D 552526 CDS YP_002123025.1 195977781 6761801 665324..666868 1 NC_011134.1 stimulates the release of release factors 1 and 2 from the ribosome after hydrolysis of the ester bond in peptidyl-tRNA has occurred; GDP/GTP-binding protein; peptide chain release factor 3 666868 prfC 6761801 prfC Streptococcus equi subsp. zooepidemicus MGCS10565 peptide chain release factor 3 YP_002123025.1 665324 D 552526 CDS YP_002123026.1 195977782 6761799 667284..668900 1 NC_011134.1 similar to ref|NP_269508.1| ATP-dependent RNA helicase [Streptococcus pyogenes M1 GAS]; Has A Helix-Destabilizing Activity. Plays A Key Role In Optimal Cell Growth At Low Temperature And Is Required For Normal Cell Division. Suppressor Of A Mutant Defective In Rpsb Gene For Ribosomal Protein S2.; ATP-dependent RNA helicase Exp9 668900 exp9 6761799 exp9 Streptococcus equi subsp. zooepidemicus MGCS10565 ATP-dependent RNA helicase Exp9 YP_002123026.1 667284 D 552526 CDS YP_002123027.1 195977783 6761798 669026..671029 1 NC_011134.1 similar to ref|YP_060497.1| Kup system potassium uptake protein [Streptococcus pyogenes MGAS10394]; Transport of potassium into the cell.; potassium transport protein Kup 671029 kup 6761798 kup Streptococcus equi subsp. zooepidemicus MGCS10565 potassium transport protein Kup YP_002123027.1 669026 D 552526 CDS YP_002123028.1 195977784 6761767 complement(671249..671530) 1 NC_011134.1 similar to ref|YP_598831.1| hypothetical protein with endo/excinuclease domain [Streptococcus pyogenes MGAS10270]; endonuclease containing a URI domain 671530 6761767 Sez_0648 Streptococcus equi subsp. zooepidemicus MGCS10565 endonuclease containing a URI domain YP_002123028.1 671249 R 552526 CDS YP_002123029.1 195977785 6761790 complement(671563..672330) 1 NC_011134.1 similar to ref|YP_280610.1| methyltransferase [Streptococcus pyogenes MGAS6180]; methyltransferase 672330 6761790 Sez_0649 Streptococcus equi subsp. zooepidemicus MGCS10565 methyltransferase YP_002123029.1 671563 R 552526 CDS YP_002123030.1 195977786 6761749 672415..673188 1 NC_011134.1 similar to ref|YP_598829.1| 1-acyl-sn-glycerol-3-phosphate acyltransferase [Streptococcus pyogenes MGAS10270]; Catalysis of the reaction: acyl-CoA + 1-acyl-sn-glycerol 3-phosphate = CoA + 1,2-diacyl-sn-glycerol 3-phosphate.; 1-acyl-Sn-glycerol-3-phosphate acyltransferase 673188 6761749 Sez_0650 Streptococcus equi subsp. zooepidemicus MGCS10565 1-acyl-Sn-glycerol-3-phosphate acyltransferase YP_002123030.1 672415 D 552526 CDS YP_002123031.1 195977787 6761719 673504..674181 1 NC_011134.1 similar to ref|YP_280608.1| ComE operon protein 1 [Streptococcus pyogenes MGAS6180]; Needed for both DNA binding and transport. It is absolutely required for the uptake of transforming DNA but not for binding. Its role in binding may be indirect.; DNA receptor late competence protein ComEA 674181 comEA 6761719 comEA Streptococcus equi subsp. zooepidemicus MGCS10565 DNA receptor late competence protein ComEA YP_002123031.1 673504 D 552526 CDS YP_002123032.1 195977788 6761788 674162..676405 1 NC_011134.1 similar to ref|YP_001128281.1| competence protein [Streptococcus pyogenes str. Manfredo]; The comE operon is required for the binding and uptake of transforming DNA. ComEC is required for internalization but is dispensable for DNA binding.; DNA transport late competence protein ComEC 676405 comEC 6761788 comEC Streptococcus equi subsp. zooepidemicus MGCS10565 DNA transport late competence protein ComEC YP_002123032.1 674162 D 552526 CDS YP_002123033.1 195977789 6761787 676518..677579 1 NC_011134.1 required for the assembly and function of the DNAX complex which is required for the assembly of the beta subunit onto primed DNA; DNA polymerase III subunit delta 677579 holA 6761787 holA Streptococcus equi subsp. zooepidemicus MGCS10565 DNA polymerase III subunit delta YP_002123033.1 676518 D 552526 CDS YP_002123034.1 195977790 6761783 677657..678262 1 NC_011134.1 similar to ref|NP_802054.1| superoxide dismutase (Fe/Mn) [Streptococcus pyogenes SSI-1]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems.; superoxide dismutase [Mn] SodA 678262 sodA 6761783 sodA Streptococcus equi subsp. zooepidemicus MGCS10565 superoxide dismutase [Mn] SodA YP_002123034.1 677657 D 552526 CDS YP_002123035.1 195977791 6761782 complement(678513..679730) 1 NC_011134.1 similar to ref|YP_282504.1| hypothetical cytosolic protein [Streptococcus pyogenes MGAS5005]; hypothetical protein 679730 6761782 Sez_0655 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123035.1 678513 R 552526 CDS YP_002123036.1 195977792 6761775 681033..681737 1 NC_011134.1 similar to ref|YP_060432.1| Glucosamine-6-phosphate isomerase [Streptococcus pyogenes MGAS10394]; Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.; glucosamine-6-phosphate deaminase 681737 nagB 6761775 nagB Streptococcus equi subsp. zooepidemicus MGCS10565 glucosamine-6-phosphate deaminase YP_002123036.1 681033 D 552526 CDS YP_002123037.1 195977793 6761773 681909..682625 1 NC_011134.1 similar to ref|YP_598817.1| Ribosomal small subunit pseudouridine synthase A [Streptococcus pyogenes MGAS10270]; Responsible for synthesis of pseudouridine from uracil- 516 in 16S ribosomal RNA.; ribosomal small subunit pseudouridine synthase A RsuA 682625 rsuA 6761773 rsuA Streptococcus equi subsp. zooepidemicus MGCS10565 ribosomal small subunit pseudouridine synthase A RsuA YP_002123037.1 681909 D 552526 CDS YP_002123038.1 195977794 6761765 682717..683694 1 NC_011134.1 similar to ref|YP_282500.1| competence protein/transcription factor [Streptococcus pyogenes MGAS5005]; competence protein/transcription factor CoiA 683694 coiA 6761765 coiA Streptococcus equi subsp. zooepidemicus MGCS10565 competence protein/transcription factor CoiA YP_002123038.1 682717 D 552526 CDS YP_002123039.1 195977795 6761763 683684..685486 1 NC_011134.1 similar to ref|YP_060429.1| Oligoendopeptidase F [Streptococcus pyogenes MGAS10394]; Has oligopeptidase activity and degrades a variety of small bioactive peptides, including bradykinin, neurotensin, and peptide fragments of substance P and adrenocorticotropin. Also hydrolyzes the synthetic collagen-like substrate N-(3-[2- furyl]acryloyl)-Leu-Gly-Pro-Ala (FALGPA).; oligoendopeptidase PepF 685486 pepF 6761763 pepF Streptococcus equi subsp. zooepidemicus MGCS10565 oligoendopeptidase PepF YP_002123039.1 683684 D 552526 CDS YP_002123040.1 195977796 6761760 685656..686213 1 NC_011134.1 similar to ref|YP_001032265.1| acetyltransferase, GNAT family [Lactococcus lactis subsp. cremoris MG1363]; GNAT family acetyltransferase 686213 6761760 Sez_0662 Streptococcus equi subsp. zooepidemicus MGCS10565 GNAT family acetyltransferase YP_002123040.1 685656 D 552526 CDS YP_002123041.1 195977797 6761757 686203..686835 1 NC_011134.1 similar to ref|ZP_00786299.1| hydrolase, haloacid dehalogenase-like family [Streptococcus agalactiae COH1]; haloacid dehalogenase-like family hydrolase 686835 6761757 Sez_0663 Streptococcus equi subsp. zooepidemicus MGCS10565 haloacid dehalogenase-like family hydrolase YP_002123041.1 686203 D 552526 CDS YP_002123042.1 195977798 6761754 686883..687524 1 NC_011134.1 similar to ref|ZP_00784655.1| hydrolase, haloacid dehalogenase-like family [Streptococcus agalactiae COH1]; Displays high phosphatase activity toward erythrose 4- phosphate, fructose 6-phosphate, 2-deoxyglucose 6-phosphate, and mannose 6-phosphate. May have a role in the intracellular metabolism of many phosphorylated carbohydrates.; phosphoglycolate phosphatase 687524 6761754 Sez_0664 Streptococcus equi subsp. zooepidemicus MGCS10565 phosphoglycolate phosphatase YP_002123042.1 686883 D 552526 CDS YP_002123043.1 195977799 6761725 687643..688314 1 NC_011134.1 similar to ref|YP_282497.1| O-methyltransferase [Streptococcus pyogenes MGAS5005]; 4-O-methyltransferase for the lactone ring of midecamycin and other macrolide antibiotics.; O-methyltransferase MdmC-like 688314 mdmC 6761725 mdmC Streptococcus equi subsp. zooepidemicus MGCS10565 O-methyltransferase MdmC-like YP_002123043.1 687643 D 552526 CDS YP_002123044.1 195977800 6761752 688377..689378 1 NC_011134.1 cis/trans isomerase of peptidylprolyl; PPIase; membrane-bound lipoprotein; foldase PrsA 689378 prsA 6761752 prsA Streptococcus equi subsp. zooepidemicus MGCS10565 foldase PrsA YP_002123044.1 688377 D 552526 CDS YP_002123045.1 195977801 6761750 689734..692352 1 NC_011134.1 Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; alanyl-tRNA synthetase 692352 alaS 6761750 alaS Streptococcus equi subsp. zooepidemicus MGCS10565 alanyl-tRNA synthetase YP_002123045.1 689734 D 552526 CDS YP_002123046.1 195977802 6761748 complement(692475..693638) 1 NC_011134.1 similar to gb|AAS09918.1| phage-encoded extracellular streptodornase D [Streptococcus pyogenes]; deoxyribonuclease; streptodornase D type, SdzD 693638 sdzD 6761748 sdzD Streptococcus equi subsp. zooepidemicus MGCS10565 streptodornase D type, SdzD YP_002123046.1 692475 R 552526 CDS YP_002123047.1 195977803 6761747 complement(693801..693944) 1 NC_011134.1 hypothetical protein 693944 6761747 Sez_0669 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123047.1 693801 R 552526 CDS YP_002123048.1 195977804 6761718 694060..695346 1 NC_011134.1 similar to ref|YP_596896.1| peptidoglycan N-acetylglucosamine deacetylase [Streptococcus pyogenes MGAS9429]; peptidoglycan N-acetylglucosamine deacetylase 695346 6761718 Sez_0670 Streptococcus equi subsp. zooepidemicus MGCS10565 peptidoglycan N-acetylglucosamine deacetylase YP_002123048.1 694060 D 552526 CDS YP_002123049.1 195977805 6761741 complement(695616..696698) 1 NC_011134.1 similar to ref|YP_280578.1| ATP-dependent RNA helicase [Streptococcus pyogenes MGAS6180]; Has A Helix-Destabilizing Activity. Plays A Key Role In Optimal Cell Growth At Low Temperature And Is Required For Normal Cell Division. Suppressor Of A Mutant Defective In Rpsb Gene For Ribosomal Protein S2.; ATP-dependent RNA helicase DEAD/DEAH box family 696698 6761741 Sez_0671 Streptococcus equi subsp. zooepidemicus MGCS10565 ATP-dependent RNA helicase DEAD/DEAH box family YP_002123049.1 695616 R 552526 CDS YP_002123050.1 195977806 6761738 696795..697421 1 NC_011134.1 functions in pyrimidine salvage; pyrimidine ribonucleoside kinase; phosphorylates nucleosides or dinucleosides to make UMP or CMP using ATP or GTP as the donor; uridine kinase 697421 udk 6761738 udk Streptococcus equi subsp. zooepidemicus MGCS10565 uridine kinase YP_002123050.1 696795 D 552526 CDS YP_002123051.1 195977807 6761732 697426..697716 1 NC_011134.1 similar to ref|ZP_01818391.1| hypothetical protein CGSSp3BS71_02178 [Streptococcus pneumoniae SP3-BS71]; hypothetical protein 697716 6761732 Sez_0673 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123051.1 697426 D 552526 CDS YP_002123052.1 195977808 6761728 complement(697910..698680) 1 NC_011134.1 similar to ref|NP_607474.1| hypothetical protein spyM18_1378 [Streptococcus pyogenes MGAS8232]; hypothetical protein 698680 6761728 Sez_0674 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123052.1 697910 R 552526 CDS YP_002123053.1 195977809 6761724 698860..699357 1 NC_011134.1 similar to ref|ZP_00365499.1| COG1956: GAF domain-containing protein [Streptococcus pyogenes M49 591]; GAF domain-containing proteins 699357 6761724 Sez_0675 Streptococcus equi subsp. zooepidemicus MGCS10565 GAF domain-containing proteins YP_002123053.1 698860 D 552526 CDS YP_002123054.1 195977810 6761702 699357..701033 1 NC_011134.1 catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the tau chain serves as a scaffold to help in the dimerizaton of the alpha,epsilon and theta core complex; the gamma chain seems to interact with the delta and delta' subunits to transfer the beta subunit on the DNA; DNA polymerase III subunits gamma and tau 701033 dnaX 6761702 dnaX Streptococcus equi subsp. zooepidemicus MGCS10565 DNA polymerase III subunits gamma and tau YP_002123054.1 699357 D 552526 CDS YP_002123055.1 195977811 6761717 701432..701617 1 NC_011134.1 similar to ref|YP_060403.1| hypothetical protein M6_Spy1085 [Streptococcus pyogenes MGAS10394]; hypothetical protein 701617 6761717 Sez_0677 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123055.1 701432 D 552526 CDS YP_002123056.1 195977812 6761715 complement(701592..702533) 1 NC_011134.1 catalyzes the formation of biotinyl-5'-AMP, also acts as a transcriptional repressor of the biotin operon; biotin--protein ligase 702533 birA 6761715 birA Streptococcus equi subsp. zooepidemicus MGCS10565 biotin--protein ligase YP_002123056.1 701592 R 552526 CDS YP_002123057.1 195977813 6761710 703060..705300 1 NC_011134.1 similar to ref|YP_001198943.1| internalin A precursor [Streptococcus suis 05ZYH33]; Mediates the entry of Listeria monocytogenes into cells.; internalin A precursor InlA 705300 inlA 6761710 inlA Streptococcus equi subsp. zooepidemicus MGCS10565 internalin A precursor InlA YP_002123057.1 703060 D 552526 CDS YP_002123058.1 195977814 6761705 705644..706849 1 NC_011134.1 catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase; S-adenosylmethionine synthetase 706849 metK 6761705 metK Streptococcus equi subsp. zooepidemicus MGCS10565 S-adenosylmethionine synthetase YP_002123058.1 705644 D 552526 CDS YP_002123059.1 195977815 6761628 706908..707042 1 NC_011134.1 hypothetical protein 707042 6761628 Sez_0681 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123059.1 706908 D 552526 CDS YP_002123060.1 195977816 6761700 707165..708424 1 NC_011134.1 adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active; UDP-N-acetylglucosamine 1-carboxyvinyltransferase 708424 murA 6761700 murA Streptococcus equi subsp. zooepidemicus MGCS10565 UDP-N-acetylglucosamine 1-carboxyvinyltransferase YP_002123060.1 707165 D 552526 CDS YP_002123061.1 195977817 6761687 708617..708784 1 NC_011134.1 hypothetical protein 708784 6761687 Sez_0683 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123061.1 708617 D 552526 CDS YP_002123062.1 195977818 6761656 708850..710394 1 NC_011134.1 similar to ref|ZP_00783009.1| sugar transporter, [Streptococcus agalactiae H36B]; glucuronide permease 710394 6761656 Sez_0684 Streptococcus equi subsp. zooepidemicus MGCS10565 glucuronide permease YP_002123062.1 708850 D 552526 CDS YP_002123063.1 195977819 6761697 710480..711508 1 NC_011134.1 similar to ref|ZP_00132613.2| COG0524: Sugar kinases, ribokinase family [Haemophilus somnus 2336]; Catalysis of the reaction: ATP + 2-dehydro-3-deoxy-D-gluconate = ADP + beta-L-arabinose 1-phosphate.; 2-dehydro-3-deoxygluconokinase 711508 6761697 Sez_0685 Streptococcus equi subsp. zooepidemicus MGCS10565 2-dehydro-3-deoxygluconokinase YP_002123063.1 710480 D 552526 CDS YP_002123064.1 195977820 6761681 711529..713319 1 NC_011134.1 similar to emb|CAI72019.1| beta-glucuronidase [Streptococcus equi subsp. zooepidemicus]; beta-D-glucuronidase 713319 6761681 Sez_0686 Streptococcus equi subsp. zooepidemicus MGCS10565 beta-D-glucuronidase YP_002123064.1 711529 D 552526 CDS YP_002123065.1 195977821 6761696 713361..714032 1 NC_011134.1 similar to ref|YP_598782.1| Transcriptional regulator, GntR family [Streptococcus pyogenes MGAS10270]; May be a regulatory protein for the LCT genes.; L-lactate dehydrogenase operon regulatory protein 714032 6761696 Sez_0687 Streptococcus equi subsp. zooepidemicus MGCS10565 L-lactate dehydrogenase operon regulatory protein YP_002123065.1 713361 D 552526 CDS YP_002123066.1 195977822 6761677 714225..714842 1 NC_011134.1 similar to ref|YP_598781.1| 4-Hydroxy-2-oxoglutarate aldolase / 2-dehydro-3-deoxyphosphogluconate aldolase [Streptococcus pyogenes MGAS10270]; Key enzyme in the Enter-Duodoroff pathway. Participates in the regulation of the intracellular level of glyoxylate.; KHG/KDPG aldolase KdgA 714842 kdgA 6761677 kdgA Streptococcus equi subsp. zooepidemicus MGCS10565 KHG/KDPG aldolase KdgA YP_002123066.1 714225 D 552526 CDS YP_002123067.1 195977823 6761694 714873..716270 1 NC_011134.1 catalyzes the interconversion of D-glucuronate to D-fructuronate or D-galacturonate to D-tagaturonate; functions in glucuronic and galacturonic metabolism; glucuronate isomerase 716270 6761694 Sez_0689 Streptococcus equi subsp. zooepidemicus MGCS10565 glucuronate isomerase YP_002123067.1 714873 D 552526 CDS YP_002123068.1 195977824 6761631 716525..717619 1 NC_011134.1 catalyzes the formation of 2-dehydro-3-deoxy-D-gluconate from mannonate; mannonate dehydratase 717619 6761631 Sez_0690 Streptococcus equi subsp. zooepidemicus MGCS10565 mannonate dehydratase YP_002123068.1 716525 D 552526 CDS YP_002123069.1 195977825 6761667 717634..718473 1 NC_011134.1 Converts D-mannonate to D-mannuronate; D-mannonate oxidoreductase 718473 6761667 Sez_0691 Streptococcus equi subsp. zooepidemicus MGCS10565 D-mannonate oxidoreductase YP_002123069.1 717634 D 552526 CDS YP_002123070.1 195977826 6761690 718727..719542 1 NC_011134.1 similar to ref|YP_598777.1| Phosphoglycolate phosphatase [Streptococcus pyogenes MGAS10270]; hydrolase HAD family 719542 6761690 Sez_0692 Streptococcus equi subsp. zooepidemicus MGCS10565 hydrolase HAD family YP_002123070.1 718727 D 552526 CDS YP_002123071.1 195977827 6761660 721791..721931 1 NC_011134.1 hypothetical protein 721931 6761660 Sez_0695 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123071.1 721791 D 552526 CDS YP_002123072.1 195977828 6761682 721988..723325 1 NC_011134.1 similar to dbj|BAD00711.2| cell surface protein precursor [Streptococcus equi subsp. zooepidemicus]; Binds to the constant Fc region of IgG with high affinity.; IgG binding protein Zag 723325 zag 6761682 zag Streptococcus equi subsp. zooepidemicus MGCS10565 IgG binding protein Zag YP_002123072.1 721988 D 552526 CDS YP_002123073.1 195977829 6761653 723620..724174 1 NC_011134.1 similar to ref|NP_735312.1| hypothetical protein gbs0862 [Streptococcus agalactiae NEM316]; GNAT family acetyltransferase 724174 6761653 Sez_0697 Streptococcus equi subsp. zooepidemicus MGCS10565 GNAT family acetyltransferase YP_002123073.1 723620 D 552526 CDS YP_002123074.1 195977830 6761678 724167..725450 1 NC_011134.1 similar to ref|YP_602697.1| Cytosolic protein containing multiple CBS domains [Streptococcus pyogenes MGAS10750]; cytosolic protein containing multiple CBS domains 725450 6761678 Sez_0698 Streptococcus equi subsp. zooepidemicus MGCS10565 cytosolic protein containing multiple CBS domains YP_002123074.1 724167 D 552526 CDS YP_002123075.1 195977831 6761680 725467..727266 1 NC_011134.1 similar to ref|YP_280563.1| methionine aminopeptidase [Streptococcus pyogenes MGAS6180]; Removes the amino-terminal methionine from nascent proteins.; methionine aminopeptidase Map 727266 map 6761680 map Streptococcus equi subsp. zooepidemicus MGCS10565 methionine aminopeptidase Map YP_002123075.1 725467 D 552526 CDS YP_002123076.1 195977832 6761672 727400..728683 1 NC_011134.1 catalyzes the formation of 5-O-(1-carboxyvinyl)-3-phosphoshikimate from phosphoenolpyruvate and 3-phosphoshikimate in tryptophan biosynthesis; 3-phosphoshikimate 1-carboxyvinyltransferase 728683 aroA 6761672 aroA Streptococcus equi subsp. zooepidemicus MGCS10565 3-phosphoshikimate 1-carboxyvinyltransferase YP_002123076.1 727400 D 552526 CDS YP_002123077.1 195977833 6761642 728676..729170 1 NC_011134.1 catalyzes the formation of shikimate 3-phosphate from shikimate in aromatic amino acid biosynthesis; shikimate kinase 729170 aroK 6761642 aroK Streptococcus equi subsp. zooepidemicus MGCS10565 shikimate kinase YP_002123077.1 728676 D 552526 CDS YP_002123078.1 195977834 6761658 729369..730799 1 NC_011134.1 similar to ref|YP_282462.1| transcriptional regulator, LytR family [Streptococcus pyogenes MGAS5005]; Cell envelope-related transcriptional attenuator.; PBP 5 synthesis repressor 730799 6761658 Sez_0702 Streptococcus equi subsp. zooepidemicus MGCS10565 PBP 5 synthesis repressor YP_002123078.1 729369 D 552526 CDS YP_002123079.1 195977835 6761657 730877..732238 1 NC_011134.1 similar to ref|YP_001128325.1| RNA methyltransferase [Streptococcus pyogenes str. Manfredo]; Could be a 23s rRNA (Uracil-5-)-Methyltransferase.; 23S rRNA-methyltransferase 732238 6761657 Sez_0703 Streptococcus equi subsp. zooepidemicus MGCS10565 23S rRNA-methyltransferase YP_002123079.1 730877 D 552526 CDS YP_002123080.1 195977836 6761654 732465..732668 1 NC_011134.1 hypothetical protein 732668 6761654 Sez_0704 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123080.1 732465 D 552526 CDS YP_002123081.1 195977837 6761651 complement(732902..733546) 1 NC_011134.1 similar to ref|YP_598099.1| Phosphoglycerate mutase family protein [Streptococcus pyogenes MGAS10270]; phosphoglycerate mutase GpmB 733546 gpmB 6761651 gpmB Streptococcus equi subsp. zooepidemicus MGCS10565 phosphoglycerate mutase GpmB YP_002123081.1 732902 R 552526 CDS YP_002123082.1 195977838 6761602 complement(733565..733912) 1 NC_011134.1 similar to ref|YP_598100.1| hypothetical protein MGAS10270_Spy0491 [Streptococcus pyogenes MGAS10270]; hypothetical protein 733912 6761602 Sez_0706 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123082.1 733565 R 552526 CDS YP_002123083.1 195977839 6761641 complement(733927..734406) 1 NC_011134.1 similar to ref|ZP_00365794.1| COG2606: Uncharacterized conserved protein [Streptococcus pyogenes M49 591]; transcriptional regulator 734406 6761641 Sez_0707 Streptococcus equi subsp. zooepidemicus MGCS10565 transcriptional regulator YP_002123083.1 733927 R 552526 CDS YP_002123084.1 195977840 6761635 complement(734567..735130) 1 NC_011134.1 similar to ref|YP_598102.1| Thiamine transporter [Streptococcus pyogenes MGAS10270]; thiamine transporter 735130 6761635 Sez_0708 Streptococcus equi subsp. zooepidemicus MGCS10565 thiamine transporter YP_002123084.1 734567 R 552526 CDS YP_002123085.1 195977841 6761583 complement(735685..736533) 1 NC_011134.1 similar to ref|YP_602013.1| N-acetylmuramoyl-L-alanine amidase [Streptococcus pyogenes MGAS10750]; N-acetylmuramoyl-L-alanine amidase 736533 6761583 Sez_0709 Streptococcus equi subsp. zooepidemicus MGCS10565 N-acetylmuramoyl-L-alanine amidase YP_002123085.1 735685 R 552526 CDS YP_002123086.1 195977842 6761608 736801..737265 1 NC_011134.1 similar to ref|YP_602014.1| Integral membrane protein [Streptococcus pyogenes MGAS10750]; hypothetical protein 737265 6761608 Sez_0710 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123086.1 736801 D 552526 CDS YP_002123087.1 195977843 6761630 complement(737464..737751) 1 NC_011134.1 hypothetical protein 737751 6761630 Sez_0711 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123087.1 737464 R 552526 CDS YP_002123088.1 195977844 6761597 complement(737829..738332) 1 NC_011134.1 similar to ref|YP_598106.1| Glutathione peroxidase [Streptococcus pyogenes MGAS10270]; Catalysis of the reaction: 2 glutathione + H2O2 = oxidized glutathione + 2 H2O.; glutathione peroxidase 738332 gpo 6761597 gpo Streptococcus equi subsp. zooepidemicus MGCS10565 glutathione peroxidase YP_002123088.1 737829 R 552526 CDS YP_002123089.1 195977845 6761623 complement(738325..740139) 1 NC_011134.1 similar to ref|YP_279952.1| oligoendopeptidase F [Streptococcus pyogenes MGAS6180]; oligoendopeptidase F-like 740139 6761623 Sez_0713 Streptococcus equi subsp. zooepidemicus MGCS10565 oligoendopeptidase F-like YP_002123089.1 738325 R 552526 CDS YP_002123090.1 195977846 6761622 740322..743105 1 NC_011134.1 catalyzes the formation of oxaloacetate from phosphoenolpyruvate; phosphoenolpyruvate carboxylase 743105 ppc 6761622 ppc Streptococcus equi subsp. zooepidemicus MGCS10565 phosphoenolpyruvate carboxylase YP_002123090.1 740322 D 552526 CDS YP_002123091.1 195977847 6761621 743310..744593 1 NC_011134.1 similar to ref|NP_606853.1| cell division protein [Streptococcus pyogenes MGAS8232]; This is a septum-peptidoglycan biosynthetic protein, involved in cell wall formation. Plays a role in the stabilization of the ftsZ ring during cell division.; cell division protein FtsW 744593 ftsW 6761621 ftsW Streptococcus equi subsp. zooepidemicus MGCS10565 cell division protein FtsW YP_002123091.1 743310 D 552526 CDS YP_002123092.1 195977848 6761620 744995..745801 1 NC_011134.1 similar to ref|YP_820727.1| Transcriptional regulator, xre family [Streptococcus thermophilus LMD-9]; positive transcriptional regulator MutR family 745801 6761620 Sez_0716 Streptococcus equi subsp. zooepidemicus MGCS10565 positive transcriptional regulator MutR family YP_002123092.1 744995 D 552526 CDS YP_002123093.1 195977849 6761569 745878..747173 1 NC_011134.1 similar to ref|YP_139930.1| hypothetical protein stu1512 [Streptococcus thermophilus LMG 18311]; transcriptional regulator 747173 6761569 Sez_0717 Streptococcus equi subsp. zooepidemicus MGCS10565 transcriptional regulator YP_002123093.1 745878 D 552526 CDS YP_002123094.1 195977850 6761589 747452..749008 1 NC_011134.1 similar to ref|YP_001034395.1| Bacteriocin ABC-type exporter, ATP binding/permease, [Streptococcus sanguinis SK36]; multidrug resistance ABC transporter ATP-binding protein/permease 749008 6761589 Sez_0718 Streptococcus equi subsp. zooepidemicus MGCS10565 multidrug resistance ABC transporter ATP-binding protein/permease YP_002123094.1 747452 D 552526 CDS YP_002123095.1 195977851 6761617 749018..750580 1 NC_011134.1 similar to ref|YP_001034395.1| Bacteriocin ABC-type exporter, ATP binding/permease, [Streptococcus sanguinis SK36]; multidrug resistance ABC transporter ATP-binding protein/permease 750580 6761617 Sez_0719 Streptococcus equi subsp. zooepidemicus MGCS10565 multidrug resistance ABC transporter ATP-binding protein/permease YP_002123095.1 749018 D 552526 CDS YP_002123096.1 195977852 6761614 complement(750644..750805) 1 NC_011134.1 hypothetical protein 750805 6761614 Sez_0720 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123096.1 750644 R 552526 CDS YP_002123097.1 195977853 6761610 751054..752070 1 NC_011134.1 recognizes the termination signals UGA and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF2; in some organisms control of PrfB protein levels is maintained through a +1 ribosomal frameshifting mechanism; this protein is similar to release factor 1; peptide chain release factor 2 752070 prfB 6761610 prfB Streptococcus equi subsp. zooepidemicus MGCS10565 peptide chain release factor 2 YP_002123097.1 751054 D 552526 CDS YP_002123098.1 195977854 6761581 752136..752813 1 NC_011134.1 similar to ref|NP_268888.1| cell-division ATP-binding protein [Streptococcus pyogenes M1 GAS]; cell division ATP-binding protein FtsE 752813 ftsE 6761581 ftsE Streptococcus equi subsp. zooepidemicus MGCS10565 cell division ATP-binding protein FtsE YP_002123098.1 752136 D 552526 CDS YP_002123099.1 195977855 6761600 752890..753735 1 NC_011134.1 similar to ref|YP_059871.1| Cell division protein FtsX [Streptococcus pyogenes MGAS10394]; cell division protein FtsX 753735 ftsX 6761600 ftsX Streptococcus equi subsp. zooepidemicus MGCS10565 cell division protein FtsX YP_002123099.1 752890 D 552526 CDS YP_002123100.1 195977856 6761596 complement(754251..754892) 1 NC_011134.1 similar to ref|YP_001197921.1| Zn-dependent hydrolase, including glyoxylases [Streptococcus suis 05ZYH33]; hydroxyacylglutathione hydrolase 754892 6761596 Sez_0724 Streptococcus equi subsp. zooepidemicus MGCS10565 hydroxyacylglutathione hydrolase YP_002123100.1 754251 R 552526 CDS YP_002123101.1 195977857 6761570 755230..757695 1 NC_011134.1 unwinds DNA; bifunctional ATP-dependent DNA helicase/DNA polymerase III subunit epsilon 757695 dinG 6761570 dinG Streptococcus equi subsp. zooepidemicus MGCS10565 bifunctional ATP-dependent DNA helicase/DNA polymerase III subunit epsilon YP_002123101.1 755230 D 552526 CDS YP_002123102.1 195977858 6761588 757807..758196 1 NC_011134.1 similar to ref|YP_001450579.1| hypothetical protein SGO_1298 [Streptococcus gordonii str. Challis substr. CH1]; hypothetical protein 758196 6761588 Sez_0726 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123102.1 757807 D 552526 CDS YP_002123103.1 195977859 6761566 758193..759404 1 NC_011134.1 catalyzes the formation of oxalozcetate and L-glutamate from L-aspartate and 2-oxoglutarate; aspartate aminotransferase 759404 6761566 Sez_0727 Streptococcus equi subsp. zooepidemicus MGCS10565 aspartate aminotransferase YP_002123103.1 758193 D 552526 CDS YP_002123104.1 195977860 6761587 759417..760763 1 NC_011134.1 catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; asparaginyl-tRNA synthetase 760763 asnC 6761587 asnC Streptococcus equi subsp. zooepidemicus MGCS10565 asparaginyl-tRNA synthetase YP_002123104.1 759417 D 552526 CDS YP_002123105.1 195977861 6761585 761064..762095 1 NC_011134.1 similar to gb|AAQ91577.1| collagen-like protein 3 [Streptococcus equi]; Possible adhesin, has a collagen-structural-motif domain composed of 62 Gly-Xaa-Yaa repeats.; hypothetical protein 762095 sclZ.8 6761585 sclZ.8 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123105.1 761064 D 552526 CDS YP_002123106.1 195977862 6761582 762624..763514 1 NC_011134.1 similar to ref|NP_268894.1| hypothetical protein SPy_0652 [Streptococcus pyogenes M1 GAS]; hypothetical protein 763514 6761582 Sez_0730 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123106.1 762624 D 552526 CDS YP_002123107.1 195977863 6761563 763511..764488 1 NC_011134.1 similar to ref|YP_279987.1| transporter [Streptococcus pyogenes MGAS6180]; hypothetical protein 764488 6761563 Sez_0731 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123107.1 763511 D 552526 CDS YP_002123108.1 195977864 6761561 764485..765396 1 NC_011134.1 similar to gb|AAK33617.1| conserved hypothetical protein [Streptococcus pyogenes M1 GAS]; hypothetical protein 765396 6761561 Sez_0732 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123108.1 764485 D 552526 CDS YP_002123109.1 195977865 6761559 765822..766097 1 NC_011134.1 similar to emb|CAA11401.1| InsA protein [Escherichia coli]; transposase IS1 orfA 766097 6761559 Sez_0733 Streptococcus equi subsp. zooepidemicus MGCS10565 transposase IS1 orfA YP_002123109.1 765822 D 552526 CDS YP_002123110.1 195977866 6761552 766016..766519 1 NC_011134.1 similar to ref|NP_414562.1| IS1 transposase InsAB' [Escherichia coli K12]; transposase IS1 orfB 766519 6761552 Sez_0734 Streptococcus equi subsp. zooepidemicus MGCS10565 transposase IS1 orfB YP_002123110.1 766016 D 552526 CDS YP_002123111.1 195977867 6761568 766539..767936 1 NC_011134.1 similar to ref|YP_279989.1| dipeptidase [Streptococcus pyogenes MGAS6180]; dipeptidase A PepDA 767936 pepDA 6761568 pepDA Streptococcus equi subsp. zooepidemicus MGCS10565 dipeptidase A PepDA YP_002123111.1 766539 D 552526 CDS YP_002123112.1 195977868 6761567 768171..769721 1 NC_011134.1 similar to ref|YP_059881.1| High-affinity zinc uptake system protein znuA precursor [Streptococcus pyogenes MGAS10394]; Part of the ATP-driven transport system adcABC for zinc.; zinc-binding lipoprotein ZnuA 769721 znuA 6761567 znuA Streptococcus equi subsp. zooepidemicus MGCS10565 zinc-binding lipoprotein ZnuA YP_002123112.1 768171 D 552526 CDS YP_002123113.1 195977869 6761565 770066..770794 1 NC_011134.1 similar to ref|YP_602121.1| Transcriptional regulator, GntR family [Streptococcus pyogenes MGAS10750]; GntR family transcriptional regulator 770794 6761565 Sez_0737 Streptococcus equi subsp. zooepidemicus MGCS10565 GntR family transcriptional regulator YP_002123113.1 770066 D 552526 CDS YP_002123114.1 195977870 6761564 770806..771981 1 NC_011134.1 similar to ref|YP_001128798.1| tagatose-6-phosphate aldose/ketose isomerase [Streptococcus pyogenes str. Manfredo]; May be a tagatose-6-phosphate ketose/aldose isomerase.; tagatose-6-phosphate ketose/aldose isomerase 771981 6761564 Sez_0738 Streptococcus equi subsp. zooepidemicus MGCS10565 tagatose-6-phosphate ketose/aldose isomerase YP_002123114.1 770806 D 552526 CDS YP_002123115.1 195977871 6761543 771991..772986 1 NC_011134.1 catalyzes the reversible reaction of dihydroxyacetone phosphate with glyceraldehyde 3-phosphate to produce tagatose 1,6-bisphosphate; in Streptococcus pyogenes there are two paralogs of tagatose-bisphosphate aldolase, encoded by lacD1 and lacD2; expression of lacD1 is highly regulated by environmental conditions while lacD2 specializes in an efficient utilization of carbohydrate sources; tagatose 1,6-diphosphate aldolase 772986 6761543 Sez_0739 Streptococcus equi subsp. zooepidemicus MGCS10565 tagatose 1,6-diphosphate aldolase YP_002123115.1 771991 D 552526 CDS YP_002123116.1 195977872 6761533 complement(773028..773747) 1 NC_011134.1 similar to ref|YP_001197814.1| Transcriptional regulator [Streptococcus suis 05ZYH33]; GntR family transcriptional regulator 773747 6761533 Sez_0740 Streptococcus equi subsp. zooepidemicus MGCS10565 GntR family transcriptional regulator YP_002123116.1 773028 R 552526 CDS YP_002123117.1 195977873 6761532 773887..775671 1 NC_011134.1 similar to ref|ZP_00875460.1| Beta-galactosidase [Streptococcus suis 89/1591]; Preferentially hydrolyzes beta(1->3) galactosyl linkages over beta(1->4) linkages.; beta-galactosidase precursor Bga 775671 bga 6761532 bga Streptococcus equi subsp. zooepidemicus MGCS10565 beta-galactosidase precursor Bga YP_002123117.1 773887 D 552526 CDS YP_002123118.1 195977874 6761556 775668..776153 1 NC_011134.1 similar to ref|YP_001197816.1| Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIB [Streptococcus suis 05ZYH33]; LevD and levE act as negative regulators of the levanase operon. They may be involved in a PTS-mediated phosphorylation of a regulator.; PTS system mannose/fructose transporter subunit IIB 776153 6761556 Sez_0742 Streptococcus equi subsp. zooepidemicus MGCS10565 PTS system mannose/fructose transporter subunit IIB YP_002123118.1 775668 D 552526 CDS YP_002123119.1 195977875 6761553 776199..777080 1 NC_011134.1 similar to ref|NP_344611.1| PTS system, IIC component [Streptococcus pneumoniae TIGR4]; The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. This system is involved in fructose transport.; PTS system mannose/fructose transporter subunit IIC 777080 6761553 Sez_0743 Streptococcus equi subsp. zooepidemicus MGCS10565 PTS system mannose/fructose transporter subunit IIC YP_002123119.1 776199 D 552526 CDS YP_002123120.1 195977876 6761529 777067..777885 1 NC_011134.1 similar to ref|ZP_00875457.1| PTS system mannose/fructose/sorbose family IID component [Streptococcus suis 89/1591]; The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. This system is involved in mannose transport.; PTS system mannose/fructose permease IID 777885 6761529 Sez_0744 Streptococcus equi subsp. zooepidemicus MGCS10565 PTS system mannose/fructose permease IID YP_002123120.1 777067 D 552526 CDS YP_002123121.1 195977877 6761526 777889..778293 1 NC_011134.1 similar to ref|ZP_00875456.1| PTS system fructose subfamily IIA component [Streptococcus suis 89/1591]; The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active-transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. This system is involved in mannose transport.; PTS system mannose/fructose transporter subunit IIAB 778293 6761526 Sez_0745 Streptococcus equi subsp. zooepidemicus MGCS10565 PTS system mannose/fructose transporter subunit IIAB YP_002123121.1 777889 D 552526 CDS YP_002123122.1 195977878 6761548 complement(778400..778660) 1 NC_011134.1 RpmE2; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster do not have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome; 50S ribosomal protein L31 778660 rpmE2 6761548 rpmE2 Streptococcus equi subsp. zooepidemicus MGCS10565 50S ribosomal protein L31 YP_002123122.1 778400 R 552526 CDS YP_002123123.1 195977879 6761545 complement(778785..779717) 1 NC_011134.1 similar to ref|YP_281910.1| phosphoesterase, DHH family protein [Streptococcus pyogenes MGAS5005]; DHH subfamily 1 protein 779717 6761545 Sez_0747 Streptococcus equi subsp. zooepidemicus MGCS10565 DHH subfamily 1 protein YP_002123123.1 778785 R 552526 CDS YP_002123124.1 195977880 6761542 complement(779727..780155) 1 NC_011134.1 similar to ref|YP_001344360.1| GCN5-related N-acetyltransferase [Actinobacillus succinogenes 130Z]; acetyltransferase 780155 6761542 Sez_0748 Streptococcus equi subsp. zooepidemicus MGCS10565 acetyltransferase YP_002123124.1 779727 R 552526 CDS YP_002123125.1 195977881 6761538 780412..781437 1 NC_011134.1 similar to ref|YP_139256.1| adenosine deaminase [Streptococcus thermophilus LMG 18311]; Catalysis of the reaction: adenosine + H2O = inosine + NH3.; adenosine deaminase 781437 add 6761538 add Streptococcus equi subsp. zooepidemicus MGCS10565 adenosine deaminase YP_002123125.1 780412 D 552526 CDS YP_002123126.1 195977882 6761537 781498..781944 1 NC_011134.1 An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group; flavodoxin 781944 6761537 Sez_0750 Streptococcus equi subsp. zooepidemicus MGCS10565 flavodoxin YP_002123126.1 781498 D 552526 CDS YP_002123127.1 195977883 6761507 782265..782561 1 NC_011134.1 similar to emb|CAM30580.1| chorismate mutase type II protein [Streptococcus pyogenes str. Manfredo]; Catalysis of the reaction: chorismate = prephenate.; hypothetical protein 782561 6761507 Sez_0751 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123127.1 782265 D 552526 CDS YP_002123128.1 195977884 6761527 782548..782784 1 NC_011134.1 similar to ref|NP_721660.1| permease, chloride channel [Streptococcus mutans UA159]; chloride channel protein 782784 6761527 Sez_0752 Streptococcus equi subsp. zooepidemicus MGCS10565 chloride channel protein YP_002123128.1 782548 D 552526 CDS YP_002123129.1 195977885 6761525 782794..783774 1 NC_011134.1 similar to ref|YP_281913.1| chloride channel protein [Streptococcus pyogenes MGAS5005]; voltage-gated chloride channel family protein 783774 6761525 Sez_0753 Streptococcus equi subsp. zooepidemicus MGCS10565 voltage-gated chloride channel family protein YP_002123129.1 782794 D 552526 CDS YP_002123130.1 195977886 6761522 783921..784268 1 NC_011134.1 this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site; 50S ribosomal protein L19 784268 rplS 6761522 rplS Streptococcus equi subsp. zooepidemicus MGCS10565 50S ribosomal protein L19 YP_002123130.1 783921 D 552526 CDS YP_002123131.1 195977887 6760664 complement(784972..785730) 1 NC_011134.1 similar to ref|YP_596326.1| streptodornase [Streptococcus pyogenes MGAS9429]; deozyribonuclease; streptodornase A type SdzA 785730 sdzA 6760664 sdzA Streptococcus equi subsp. zooepidemicus MGCS10565 streptodornase A type SdzA YP_002123131.1 784972 R 552526 CDS YP_002123132.1 195977888 6761523 785896..786108 1 NC_011134.1 similar to ref|YP_598462.1| phage protein [Streptococcus phage 10270.2]; paratox phage protein 786108 ptx 6761523 ptx Streptococcus equi subsp. zooepidemicus MGCS10565 paratox phage protein YP_002123132.1 785896 D 552526 CDS YP_002123133.1 195977889 6761519 786390..786605 1 NC_011134.1 similar to ref|NP_664861.1| transcriptional regulator protein [Streptococcus pyogenes MGAS315]; Cro/CI family transcriptional regulator 786605 6761519 Sez_0757 Streptococcus equi subsp. zooepidemicus MGCS10565 Cro/CI family transcriptional regulator YP_002123133.1 786390 D 552526 CDS YP_002123134.1 195977890 6761510 786683..787378 1 NC_011134.1 similar to ref|ZP_00785582.1| membrane protein, [Streptococcus agalactiae COH1]; hypothetical protein 787378 6761510 Sez_0758 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123134.1 786683 D 552526 CDS YP_002123135.1 195977891 6761492 complement(787448..788659) 1 NC_011134.1 similar to ref|YP_598804.1| Chloride channel protein [Streptococcus pyogenes MGAS10270]; chloride channel protein 788659 6761492 Sez_0759 Streptococcus equi subsp. zooepidemicus MGCS10565 chloride channel protein YP_002123135.1 787448 R 552526 CDS YP_002123136.1 195977892 6761508 complement(788789..789748) 1 NC_011134.1 B2 or R2 protein; type 1b enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdE; ribonucleotide-diphosphate reductase subunit beta 789748 nrdF 6761508 nrdF Streptococcus equi subsp. zooepidemicus MGCS10565 ribonucleotide-diphosphate reductase subunit beta YP_002123136.1 788789 R 552526 CDS YP_002123137.1 195977893 6761504 complement(792100..792276) 1 NC_011134.1 similar to ref|NP_802075.1| glutaredoxin [Streptococcus pyogenes SSI-1]; Electron transport system for the ribonucleotide reductase system nrdEF.; glutaredoxin-like protein NrdH 792276 nrdH 6761504 nrdH Streptococcus equi subsp. zooepidemicus MGCS10565 glutaredoxin-like protein NrdH YP_002123137.1 792100 R 552526 CDS YP_002123138.1 195977894 6761500 792740..793003 1 NC_011134.1 similar to ref|YP_329567.1| phosphocarrier protein HPr [Streptococcus agalactiae A909]; P-Ser-HPr interacts with the catabolite control protein A (ccpA), forming a complex that binds to DNA at the catabolite reponse elements cre, operator sites preceding a large number of catabolite-regulated genes. Thus, P-Ser-HPr is a corepressor in carbon catabolite repression (CCR), a mechanism that allows bacteria to coordinate and optimise the utilization of available carbon sources. P-Ser-HPr also plays a role in inducer exclusion, in which it probably interacts with several non-PTS permeases and inhibits their transport activity.; phosphocarrier protein HPr 793003 ptsH 6761500 ptsH Streptococcus equi subsp. zooepidemicus MGCS10565 phosphocarrier protein HPr YP_002123138.1 792740 D 552526 CDS YP_002123139.1 195977895 6761498 793008..794741 1 NC_011134.1 similar to ref|NP_269478.1| phosphoenolpyruvate:sugar phosphotransferase system enzyme I [Streptococcus pyogenes M1 GAS]; This is a component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr). Enzyme I is common to all PTS.; phosphoenolpyruvate-protein phosphotransferase PtsI 794741 ptsI 6761498 ptsI Streptococcus equi subsp. zooepidemicus MGCS10565 phosphoenolpyruvate-protein phosphotransferase PtsI YP_002123139.1 793008 D 552526 CDS YP_002123140.1 195977896 6761483 794941..796368 1 NC_011134.1 similar to ref|YP_001128305.1| NADP-dependent glyceraldehyde-3-phosphate dehydrogenase [Streptococcus pyogenes str. Manfredo]; 4-aminobutyrate (GABA) degradation.; NADP-dependent glyceraldehyde-3-phosphate dehydrogenase GapN 796368 gapN 6761483 gapN Streptococcus equi subsp. zooepidemicus MGCS10565 NADP-dependent glyceraldehyde-3-phosphate dehydrogenase GapN YP_002123140.1 794941 D 552526 CDS YP_002123141.1 195977897 6761494 797019..798233 1 NC_011134.1 similar to ref|ZP_00790437.1| cell division protein, FtsW/RodA/SpoVE family [Streptococcus agalactiae 515]; cell division protein FtsW 798233 ftsW 6761494 ftsW Streptococcus equi subsp. zooepidemicus MGCS10565 cell division protein FtsW YP_002123141.1 797019 D 552526 CDS YP_002123142.1 195977898 6761493 798348..798899 1 NC_011134.1 similar to ref|YP_280000.1| DNA gyrase related protein [Streptococcus pyogenes MGAS6180]; hydrolase HAD family 798899 6761493 Sez_0768 Streptococcus equi subsp. zooepidemicus MGCS10565 hydrolase HAD family YP_002123142.1 798348 D 552526 CDS YP_002123143.1 195977899 6761476 798900..800852 1 NC_011134.1 negatively supercoils closed circular double-stranded DNA; DNA gyrase subunit B 800852 gyrB 6761476 gyrB Streptococcus equi subsp. zooepidemicus MGCS10565 DNA gyrase subunit B YP_002123143.1 798900 D 552526 CDS YP_002123144.1 195977900 6761491 801001..802725 1 NC_011134.1 acts to negatively regulates ftsZ ring formation by modulating the frequency and position of the ftsZ ring formation; septation ring formation regulator EzrA 802725 ezrA 6761491 ezrA Streptococcus equi subsp. zooepidemicus MGCS10565 septation ring formation regulator EzrA YP_002123144.1 801001 D 552526 CDS YP_002123145.1 195977901 6761489 802762..802950 1 NC_011134.1 hypothetical protein 802950 6761489 Sez_0771 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123145.1 802762 D 552526 CDS YP_002123146.1 195977902 6761490 803098..803373 1 NC_011134.1 hypothetical protein 803373 6761490 Sez_0772 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123146.1 803098 D 552526 CDS YP_002123147.1 195977903 6761472 complement(803557..804030) 1 NC_011134.1 similar to ref|YP_598223.1| hypothetical cytosolic protein [Streptococcus pyogenes MGAS10270]; hypothetical protein 804030 6761472 Sez_0773 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123147.1 803557 R 552526 CDS YP_002123148.1 195977904 6761486 804244..805551 1 NC_011134.1 enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis; phosphopyruvate hydratase 805551 eno 6761486 eno Streptococcus equi subsp. zooepidemicus MGCS10565 phosphopyruvate hydratase YP_002123148.1 804244 D 552526 CDS YP_002123149.1 195977905 6761484 806572..806793 1 NC_011134.1 similar to ref|YP_001198867.1| hypothetical protein SSU05_1501 [Streptococcus suis 05ZYH33]; hypothetical protein 806793 6761484 Sez_0776 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123149.1 806572 D 552526 CDS YP_002123150.1 195977906 6761466 806795..807055 1 NC_011134.1 similar to ref|YP_001198866.1| Cytotoxic translational repressor of toxin-antitoxin stability system [Streptococcus suis 05ZYH33]; plasmid addiction system poison protein 807055 6761466 Sez_0777 Streptococcus equi subsp. zooepidemicus MGCS10565 plasmid addiction system poison protein YP_002123150.1 806795 D 552526 CDS YP_002123151.1 195977907 6761478 807135..807650 1 NC_011134.1 similar to ref|NP_688076.1| IS861, transposase OrfA [Streptococcus agalactiae 2603V/R]; transposase IS861 orfA 807650 6761478 Sez_0778 Streptococcus equi subsp. zooepidemicus MGCS10565 transposase IS861 orfA YP_002123151.1 807135 D 552526 CDS YP_002123152.1 195977908 6761479 807647..808366 1 NC_011134.1 similar to ref|NP_721000.1| transposase, ISSmu1 [Streptococcus mutans UA159]; transposase IS861 orfB 808366 6761479 Sez_0779 Streptococcus equi subsp. zooepidemicus MGCS10565 transposase IS861 orfB YP_002123152.1 807647 D 552526 CDS YP_002123153.1 195977909 6761477 808548..808808 1 NC_011134.1 similar to gb|AAA37416.1| complement factor H-related protein; hypothetical protein 808808 6761477 Sez_0780 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123153.1 808548 D 552526 CDS YP_002123154.1 195977910 6761460 808836..811616 1 NC_011134.1 similar to ref|YP_596357.1| endonuclease/exonuclease/phosphatase family protein [Streptococcus pyogenes MGAS9429]; extracellular nuclease 811616 6761460 Sez_0781 Streptococcus equi subsp. zooepidemicus MGCS10565 extracellular nuclease YP_002123154.1 808836 D 552526 CDS YP_002123155.1 195977911 6761430 812206..812328 1 NC_011134.1 hypothetical protein 812328 6761430 Sez_0782 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123155.1 812206 D 552526 CDS YP_002123156.1 195977912 6761459 812419..812925 1 NC_011134.1 similar to ref|ZP_00365711.1| COG4708: Predicted membrane protein [Streptococcus pyogenes M49 591]; hypothetical protein 812925 6761459 Sez_0783 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123156.1 812419 D 552526 CDS YP_002123157.1 195977913 6761473 813022..814980 1 NC_011134.1 this protein catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction; essential for DNA replication and repair of damaged DNA; similar to ligase LigB; NAD-dependent DNA ligase LigA 814980 ligA 6761473 ligA Streptococcus equi subsp. zooepidemicus MGCS10565 NAD-dependent DNA ligase LigA YP_002123157.1 813022 D 552526 CDS YP_002123158.1 195977914 6761471 814993..816015 1 NC_011134.1 similar to YegS from E. coli; lipid kinase 816015 6761471 Sez_0785 Streptococcus equi subsp. zooepidemicus MGCS10565 lipid kinase YP_002123158.1 814993 D 552526 CDS YP_002123159.1 195977915 6761452 816024..818324 1 NC_011134.1 similar to ref|NP_721883.1| glycogen branching enzyme [Streptococcus mutans UA159]; Hydrolyzes the alpha-1,6-glucosidic linkages in glycogen which has first been partially depolymerized by phosphorylase. Shows only very little activity with native glycogen.; glycogen debranching enzyme / pullulanase PulA 818324 pulA 6761452 pulA Streptococcus equi subsp. zooepidemicus MGCS10565 glycogen debranching enzyme / pullulanase PulA YP_002123159.1 816024 D 552526 CDS YP_002123160.1 195977916 6761450 818471..820351 1 NC_011134.1 catalyzes the transfer of a segment of a 1,4-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain; glycogen branching protein 820351 glgB 6761450 glgB Streptococcus equi subsp. zooepidemicus MGCS10565 glycogen branching protein YP_002123160.1 818471 D 552526 CDS YP_002123161.1 195977917 6761469 820428..821555 1 NC_011134.1 catalyzes the formation of ADP-glucose and diphosphate from ATP and alpha-D-glucose 1-phosphate; glucose-1-phosphate adenylyltransferase 821555 glgC 6761469 glgC Streptococcus equi subsp. zooepidemicus MGCS10565 glucose-1-phosphate adenylyltransferase YP_002123161.1 820428 D 552526 CDS YP_002123162.1 195977918 6761436 821545..822678 1 NC_011134.1 similar to ref|NP_721881.1| glycogen biosynthesis protein GlgD [Streptococcus mutans UA159]; Required for the synthesis of glycogen, glucose-1-phosphate adenylyltransferase.; glycogen biosynthesis protein GlgD 822678 glgD 6761436 glgD Streptococcus equi subsp. zooepidemicus MGCS10565 glycogen biosynthesis protein GlgD YP_002123162.1 821545 D 552526 CDS YP_002123163.1 195977919 6761435 822684..824105 1 NC_011134.1 catalyzes the formation of alpha-1,4-glucan chains from ADP-glucose; glycogen synthase 824105 glgA 6761435 glgA Streptococcus equi subsp. zooepidemicus MGCS10565 glycogen synthase YP_002123163.1 822684 D 552526 CDS YP_002123164.1 195977920 6761461 824118..826520 1 NC_011134.1 similar to ref|NP_721879.1| glycogen phosphorylase [Streptococcus mutans UA159]; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.; glycogen phosphorylase GlgP 826520 glgP 6761461 glgP Streptococcus equi subsp. zooepidemicus MGCS10565 glycogen phosphorylase GlgP YP_002123164.1 824118 D 552526 CDS YP_002123165.1 195977921 6761462 826862..827059 1 NC_011134.1 produces ATP from ADP in the presence of a proton gradient across the membrane; subunit C is part of the membrane proton channel F0; ATP synthase F0F1 subunit C 827059 atpE 6761462 atpE Streptococcus equi subsp. zooepidemicus MGCS10565 ATP synthase F0F1 subunit C YP_002123165.1 826862 D 552526 CDS YP_002123166.1 195977922 6761432 827093..827809 1 NC_011134.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0; ATP synthase F0F1 subunit A 827809 atpB 6761432 atpB Streptococcus equi subsp. zooepidemicus MGCS10565 ATP synthase F0F1 subunit A YP_002123166.1 827093 D 552526 CDS YP_002123167.1 195977923 6761457 827827..828321 1 NC_011134.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit B is part of the membrane proton channel.; ATP synthase F0F1 subunit B 828321 atpF 6761457 atpF Streptococcus equi subsp. zooepidemicus MGCS10565 ATP synthase F0F1 subunit B YP_002123167.1 827827 D 552526 CDS YP_002123168.1 195977924 6761455 828321..828857 1 NC_011134.1 Produces ATP from ADP in the presence of a proton gradient across the membrane; the delta subunit is part of the catalytic core of the ATP synthase complex; ATP synthase F0F1 subunit delta 828857 atpH 6761455 atpH Streptococcus equi subsp. zooepidemicus MGCS10565 ATP synthase F0F1 subunit delta YP_002123168.1 828321 D 552526 CDS YP_002123169.1 195977925 6761454 828873..830378 1 NC_011134.1 produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit; ATP synthase F0F1 subunit alpha 830378 atpA 6761454 atpA Streptococcus equi subsp. zooepidemicus MGCS10565 ATP synthase F0F1 subunit alpha YP_002123169.1 828873 D 552526 CDS YP_002123170.1 195977926 6761442 830395..831270 1 NC_011134.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is a regulatory subunit; ATP synthase F0F1 subunit gamma 831270 atpG 6761442 atpG Streptococcus equi subsp. zooepidemicus MGCS10565 ATP synthase F0F1 subunit gamma YP_002123170.1 830395 D 552526 CDS YP_002123171.1 195977927 6761389 831438..832844 1 NC_011134.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit; ATP synthase F0F1 subunit beta 832844 atpD 6761389 atpD Streptococcus equi subsp. zooepidemicus MGCS10565 ATP synthase F0F1 subunit beta YP_002123171.1 831438 D 552526 CDS YP_002123172.1 195977928 6761411 832857..833273 1 NC_011134.1 part of catalytic core of ATP synthase; alpha(3)beta(3)gamma(1)delta(1)epsilon(1); involved in producing ATP from ADP in the presence of the proton motive force across the membrane; ATP synthase F0F1 subunit epsilon 833273 atpC 6761411 atpC Streptococcus equi subsp. zooepidemicus MGCS10565 ATP synthase F0F1 subunit epsilon YP_002123172.1 832857 D 552526 CDS YP_002123173.1 195977929 6761431 833431..833643 1 NC_011134.1 similar to ref|YP_059918.1| Hypothetical membrane associated protein [Streptococcus pyogenes MGAS10394]; hypothetical protein 833643 6761431 Sez_0800 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123173.1 833431 D 552526 CDS YP_002123174.1 195977930 6761406 833695..834978 1 NC_011134.1 adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active; UDP-N-acetylglucosamine 1-carboxyvinyltransferase 834978 murA 6761406 murA Streptococcus equi subsp. zooepidemicus MGCS10565 UDP-N-acetylglucosamine 1-carboxyvinyltransferase YP_002123174.1 833695 D 552526 CDS YP_002123175.1 195977931 6761428 835018..835170 1 NC_011134.1 similar to gb|AAK33707.1| conserved competence associated hypothetical protein [Streptococcus pyogenes M1 GAS]; EpuA 835170 epuA 6761428 epuA Streptococcus equi subsp. zooepidemicus MGCS10565 EpuA YP_002123175.1 835018 D 552526 CDS YP_002123176.1 195977932 6761427 835187..836080 1 NC_011134.1 similar to ref|YP_139616.1| competence associated membrane nuclease [Streptococcus thermophilus LMG 18311]; By degrading DNA that enters the cell, plays a role in the competence of cells to be transformed.; DNA-entry nuclease EndA 836080 endA 6761427 endA Streptococcus equi subsp. zooepidemicus MGCS10565 DNA-entry nuclease EndA YP_002123176.1 835187 D 552526 CDS YP_002123177.1 195977933 6761423 836094..836252 1 NC_011134.1 hypothetical protein 836252 6761423 Sez_0804 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123177.1 836094 D 552526 CDS YP_002123178.1 195977934 6761422 836995..838038 1 NC_011134.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily; phenylalanyl-tRNA synthetase subunit alpha 838038 pheS 6761422 pheS Streptococcus equi subsp. zooepidemicus MGCS10565 phenylalanyl-tRNA synthetase subunit alpha YP_002123178.1 836995 D 552526 CDS YP_002123179.1 195977935 6761416 838228..840633 1 NC_011134.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily; phenylalanyl-tRNA synthetase subunit beta 840633 pheT 6761416 pheT Streptococcus equi subsp. zooepidemicus MGCS10565 phenylalanyl-tRNA synthetase subunit beta YP_002123179.1 838228 D 552526 CDS YP_002123180.1 195977936 6761390 840870..841946 1 NC_011134.1 similar to ref|YP_001128757.1| permease [Streptococcus pyogenes str. Manfredo]; ABC transporter permease 841946 6761390 Sez_0807 Streptococcus equi subsp. zooepidemicus MGCS10565 ABC transporter permease YP_002123180.1 840870 D 552526 CDS YP_002123181.1 195977937 6761415 841956..842660 1 NC_011134.1 similar to dbj|BAF45146.1| ABC transporter ATP-binding protein [Streptococcus equi subsp. zooepidemicus]; ABC transporter ATP-binding protein 842660 6761415 Sez_0808 Streptococcus equi subsp. zooepidemicus MGCS10565 ABC transporter ATP-binding protein YP_002123181.1 841956 D 552526 CDS YP_002123182.1 195977938 6761408 843000..844133 1 NC_011134.1 similar to gb|AAD37432.1|AF150748_1 M-like protein precursor [Streptococcus equi subsp. zooepidemicus]; Major surface antigen likely antiphagocytic providing resitancew to host immune response.; M-like proptein Szp 844133 szp 6761408 szp Streptococcus equi subsp. zooepidemicus MGCS10565 M-like proptein Szp YP_002123182.1 843000 D 552526 CDS YP_002123183.1 195977939 6761407 complement(844295..844870) 1 NC_011134.1 similar to dbj|BAF45148.1| TetR family transcriptional regulator [Streptococcus equi subsp. zooepidemicus]; TetR family transcriptional regulator 844870 6761407 Sez_0810 Streptococcus equi subsp. zooepidemicus MGCS10565 TetR family transcriptional regulator YP_002123183.1 844295 R 552526 CDS YP_002123184.1 195977940 6761379 844924..846921 1 NC_011134.1 similar to gb|AAO43099.1| collagen-binding protein Cne precursor [Streptococcus equi subsp. equi]; Mediates attachment of cells to collagen- containing substrata, fimbrial protein.; fimbrial subunit A protein FszA 846921 fszA 6761379 fszA Streptococcus equi subsp. zooepidemicus MGCS10565 fimbrial subunit A protein FszA YP_002123184.1 844924 D 552526 CDS YP_002123185.1 195977941 6761399 846936..848372 1 NC_011134.1 similar to gb|AAM77659.1|AF521601_1 surface protein se51.9 [Streptococcus equi]; Fimbrial subunit-like protein, adhesin.; fimbrial subunit B protein FszB 848372 fszB 6761399 fszB Streptococcus equi subsp. zooepidemicus MGCS10565 fimbrial subunit B protein FszB YP_002123185.1 846936 D 552526 CDS YP_002123186.1 195977942 6761397 848453..849262 1 NC_011134.1 similar to ref|YP_001035569.1| Sortase-like protein, [Streptococcus sanguinis SK36]; Fimbrial associated sortase required for polymerization of fimbrial subunits.; sortase 849262 srtC.1 6761397 srtC.1 Streptococcus equi subsp. zooepidemicus MGCS10565 sortase YP_002123186.1 848453 D 552526 CDS YP_002123187.1 195977943 6761370 849577..850755 1 NC_011134.1 similar to pdb|2AU1|A Chain A, Crystal Structure Of Group A Streptococcus Mac-1 Orthorhombic Form; Virulence protein involved in evasion of the host immune response.; Mac-1-like IgG-degrading endopeptidase IdeZ 850755 ideZ 6761370 ideZ Streptococcus equi subsp. zooepidemicus MGCS10565 Mac-1-like IgG-degrading endopeptidase IdeZ YP_002123187.1 849577 D 552526 CDS YP_002123188.1 195977944 6761394 850835..852037 1 NC_011134.1 similar to emb|CAA36712.1| proline-rich protein [Triticum aestivum]; hypothetical protein 852037 6761394 Sez_0815 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123188.1 850835 D 552526 CDS YP_002123189.1 195977945 6761395 complement(852207..852755) 1 NC_011134.1 similar to ref|ZP_01817173.1| hypothetical protein CGSSp3BS71_06969 [Streptococcus pneumoniae SP3-BS71]; hypothetical protein 852755 6761395 Sez_0816 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123189.1 852207 R 552526 CDS YP_002123190.1 195977946 6761367 complement(852748..853035) 1 NC_011134.1 similar to ref|NP_344990.1| hypothetical protein SP_0471 [Streptococcus pneumoniae TIGR4]; hypothetical protein 853035 6761367 Sez_0817 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123190.1 852748 R 552526 CDS YP_002123191.1 195977947 6761388 complement(853035..853418) 1 NC_011134.1 hypothetical protein 853418 6761388 Sez_0818 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123191.1 853035 R 552526 CDS YP_002123192.1 195977948 6761385 854598..858314 1 NC_011134.1 similar to ref|YP_001034451.1| Type II secretory pathway, pullulanase PulA glycosidase, [Streptococcus sanguinis SK36]; Hydrolyzes The Alpha-1,6-Glucosidic Linkages In Glycogen Which Has First Been Partially Depolymerized By Phosphorylase. Shows Only Very Little Activity With Native Glycogen.; pullulanase precursor PulA 858314 pulA 6761385 pulA Streptococcus equi subsp. zooepidemicus MGCS10565 pullulanase precursor PulA YP_002123192.1 854598 D 552526 CDS YP_002123193.1 195977949 6761358 858603..859142 1 NC_011134.1 similar to ref|ZP_01573929.1| RNA polymerase, sigma-24 subunit, ECF subfamily [Clostridium cellulolyticum H10]; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in heat shock and oxidative stress response; it is believed to control protein processing in the extracytoplasmic compartment.; RNA polymerase sigma-E factor RpoE 859142 rpoE 6761358 rpoE Streptococcus equi subsp. zooepidemicus MGCS10565 RNA polymerase sigma-E factor RpoE YP_002123193.1 858603 D 552526 CDS YP_002123194.1 195977950 6761376 859189..859767 1 NC_011134.1 hypothetical protein 859767 6761376 Sez_0822 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123194.1 859189 D 552526 CDS YP_002123195.1 195977951 6761378 859826..860590 1 NC_011134.1 similar to ref|NP_688548.1| hypothetical protein SAG1555 [Streptococcus agalactiae 2603V/R]; hypothetical protein 860590 6761378 Sez_0823 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123195.1 859826 D 552526 CDS YP_002123196.1 195977952 6761377 860604..861281 1 NC_011134.1 similar to ref|ZP_00783577.1| conserved hypothetical protein [Streptococcus agalactiae H36B]; hypothetical protein 861281 6761377 Sez_0824 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123196.1 860604 D 552526 CDS YP_002123197.1 195977953 6761372 861287..862720 1 NC_011134.1 similar to ref|ZP_00783579.1| Unknown [Streptococcus agalactiae H36B]; hypothetical protein 862720 6761372 Sez_0825 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123197.1 861287 D 552526 CDS YP_002123198.1 195977954 6760895 862727..864868 1 NC_011134.1 similar to gb|ABA44760.1| conserved hypothetical protein [Streptococcus agalactiae A909]; hypothetical protein 864868 6760895 Sez_0826 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123198.1 862727 D 552526 CDS YP_002123199.1 195977955 6760997 865015..866409 1 NC_011134.1 similar to ref|YP_330175.1| glycosyl transferase, group 2 family protein [Streptococcus agalactiae A909]; glycosyl transferase family protein 866409 6760997 Sez_0827 Streptococcus equi subsp. zooepidemicus MGCS10565 glycosyl transferase family protein YP_002123199.1 865015 D 552526 CDS YP_002123200.1 195977956 6760438 866527..869841 1 NC_011134.1 similar to ref|YP_280042.1| ATP-dependent nuclease subunit B [Streptococcus pyogenes MGAS6180]; The enzyme complex may have a wide variety of catalytic activities including ATP-dependent exonuclease, ATP-stimulated endonuclease, ATP-dependent helicase and DNA-dependent ATPase activities.; ATP-dependent nuclease subunit B AddB 869841 addB 6760438 addB Streptococcus equi subsp. zooepidemicus MGCS10565 ATP-dependent nuclease subunit B AddB YP_002123200.1 866527 D 552526 CDS YP_002123201.1 195977957 6762157 869831..873475 1 NC_011134.1 similar to ref|NP_664318.1| ATP-dependent exonuclease subunit A [Streptococcus pyogenes MGAS315]; The enzyme complex may have a wide variety of catalytic activities including ATP-dependent exonuclease, ATP-stimulated endonuclease, ATP-dependent helicase and DNA-dependent ATPase activities. The subunit A may have a role in DNA unwinding (helicase), and in the nuclease activity.; ATP-dependent nuclease subunit A AddA 873475 addA 6762157 addA Streptococcus equi subsp. zooepidemicus MGCS10565 ATP-dependent nuclease subunit A AddA YP_002123201.1 869831 D 552526 CDS YP_002123202.1 195977958 6760585 873741..874856 1 NC_011134.1 associated with arginine deiminase pathway genes; probably functions in arginine catabolism; transaminase 874856 aspC 6760585 aspC Streptococcus equi subsp. zooepidemicus MGCS10565 transaminase YP_002123202.1 873741 D 552526 CDS YP_002123203.1 195977959 6760631 874924..875736 1 NC_011134.1 similar to ref|YP_330074.1| polar amino acid uptake (PAAT) family ABC transporter, amino acid-binding protein [Streptococcus agalactiae A909]; Probably part of a binding-protein-dependent transport system for an amino acid.; amino acid ABC transporter, amino acid-binding/permease 875736 6760631 Sez_0831 Streptococcus equi subsp. zooepidemicus MGCS10565 amino acid ABC transporter, amino acid-binding/permease YP_002123203.1 874924 D 552526 CDS YP_002123204.1 195977960 6760559 875873..876079 1 NC_011134.1 a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA; 30S ribosomal protein S21 876079 rpsU 6760559 rpsU Streptococcus equi subsp. zooepidemicus MGCS10565 30S ribosomal protein S21 YP_002123204.1 875873 D 552526 CDS YP_002123205.1 195977961 6762219 complement(876307..876681) 1 NC_011134.1 similar to ref|NP_268999.1| large conductance mechanosensitive channel [Streptococcus pyogenes M1 GAS]; Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.; large-conductance mechanosensitive channel MscL 876681 mscL 6762219 mscL Streptococcus equi subsp. zooepidemicus MGCS10565 large-conductance mechanosensitive channel MscL YP_002123205.1 876307 R 552526 CDS YP_002123206.1 195977962 6762199 876928..878739 1 NC_011134.1 synthesizes RNA primers at the replication forks; DNA primase 878739 dnaG 6762199 dnaG Streptococcus equi subsp. zooepidemicus MGCS10565 DNA primase YP_002123206.1 876928 D 552526 CDS YP_002123207.1 195977963 6760901 878748..879857 1 NC_011134.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; primary sigma factor of bacterium; RNA polymerase sigma factor RpoD 879857 rpoD 6760901 rpoD Streptococcus equi subsp. zooepidemicus MGCS10565 RNA polymerase sigma factor RpoD YP_002123207.1 878748 D 552526 CDS YP_002123208.1 195977964 6762229 880176..880547 1 NC_011134.1 similar to ref|NP_269002.1| hypothetical protein SPy_0783 [Streptococcus pyogenes M1 GAS]; hypothetical protein 880547 6762229 Sez_0836 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123208.1 880176 D 552526 CDS YP_002123209.1 195977965 6760900 880688..881536 1 NC_011134.1 similar to ref|YP_602183.1| dTDP-4-dehydrorhamnose reductase [Streptococcus pyogenes MGAS10750]; Catalysis of the reaction: dTDP-6-deoxy-L-mannose + NADP+ = dTDP-4-dehydro-6-deoxy-L-mannose + NADPH + H+.; dTDP-4-dehydrorhamnose reductase 881536 6760900 Sez_0837 Streptococcus equi subsp. zooepidemicus MGCS10565 dTDP-4-dehydrorhamnose reductase YP_002123209.1 880688 D 552526 CDS YP_002123210.1 195977966 6760904 881661..882815 1 NC_011134.1 similar to ref|YP_059938.1| alpha-D-GlcNAc alpha-1,2-L-rhamnosyltransferase [Streptococcus pyogenes MGAS10394]; alpha-D-GlcNAc alpha-1,2-L-rhamnosyltransferase 882815 6760904 Sez_0838 Streptococcus equi subsp. zooepidemicus MGCS10565 alpha-D-GlcNAc alpha-1,2-L-rhamnosyltransferase YP_002123210.1 881661 D 552526 CDS YP_002123211.1 195977967 6762250 882805..883740 1 NC_011134.1 similar to ref|YP_598268.1| alpha-L-Rha alpha-1,3-L-rhamnosyltransferase [Streptococcus pyogenes MGAS10270]; alpha-L-Rha alpha-1,3-L-rhamnosyltransferase 883740 6762250 Sez_0839 Streptococcus equi subsp. zooepidemicus MGCS10565 alpha-L-Rha alpha-1,3-L-rhamnosyltransferase YP_002123211.1 882805 D 552526 CDS YP_002123212.1 195977968 6762227 883740..884543 1 NC_011134.1 similar to ref|YP_281968.1| polysaccharide export ABC transporter permease [Streptococcus pyogenes MGAS5005]; Possibly involved in GCS group carbohydrate antigen synthesis.; rhamnose-containing polysacharide translocation permease 884543 6762227 Sez_0840 Streptococcus equi subsp. zooepidemicus MGCS10565 rhamnose-containing polysacharide translocation permease YP_002123212.1 883740 D 552526 CDS YP_002123213.1 195977969 6762275 884543..885751 1 NC_011134.1 similar to ref|ZP_00366290.1| COG1134: ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Streptococcus pyogenes M49 591]; Possibly involved in cell wall localization and side chain formation of rhamnose-glucose polysaccharide.; ABC transporter ATP-binding protein 885751 6762275 Sez_0841 Streptococcus equi subsp. zooepidemicus MGCS10565 ABC transporter ATP-binding protein YP_002123213.1 884543 D 552526 CDS YP_002123214.1 195977970 6762233 885772..886779 1 NC_011134.1 similar to ref|YP_001128742.1| glycosyltransferase [Streptococcus pyogenes str. Manfredo]; Possibly involved in cell wall localization and side chain formation of rhamnose-glucose polysaccharide.; glycosyltransferase 886779 6762233 Sez_0842 Streptococcus equi subsp. zooepidemicus MGCS10565 glycosyltransferase YP_002123214.1 885772 D 552526 CDS YP_002123215.1 195977971 6762281 886776..888521 1 NC_011134.1 similar to ref|YP_001128741.1| rhamnan synthesis protein F family protein [Streptococcus pyogenes str. Manfredo]; Possibly involved in synthesis of the GCS carbohydrate group antigen.; alpha-L-Rha alpha-1,3-L-rhamnosyltransferase 888521 6762281 Sez_0843 Streptococcus equi subsp. zooepidemicus MGCS10565 alpha-L-Rha alpha-1,3-L-rhamnosyltransferase YP_002123215.1 886776 D 552526 CDS YP_002123216.1 195977972 6762241 888551..889240 1 NC_011134.1 similar to ref|YP_141826.1| glycosyl transferase [Streptococcus thermophilus CNRZ1066]; Possibly involved in synthesis of the GCS carbohydrate group antigen.; glycosyl transferase family protein 889240 6762241 Sez_0844 Streptococcus equi subsp. zooepidemicus MGCS10565 glycosyl transferase family protein YP_002123216.1 888551 D 552526 CDS YP_002123217.1 195977973 6760907 889245..889601 1 NC_011134.1 similar to ref|YP_141825.1| hypothetical protein str1475 [Streptococcus thermophilus CNRZ1066]; Possibly involved in synthesis of the GCS carbohydrate group antigen.; glycosyltransferase, lytic transglycosylase, dTDP-4-rhamnose reductase 889601 6760907 Sez_0845 Streptococcus equi subsp. zooepidemicus MGCS10565 glycosyltransferase, lytic transglycosylase, dTDP-4-rhamnose reductase YP_002123217.1 889245 D 552526 CDS YP_002123218.1 195977974 6762228 889636..890826 1 NC_011134.1 similar to ref|YP_001128737.1| exopolysaccharide biosynthesis protein [Streptococcus pyogenes str. Manfredo]; Possibly involved in synthesis of the GCS carbohydrate group antigen.; heteropolysaccharide repeat unit export protein 890826 6762228 Sez_0846 Streptococcus equi subsp. zooepidemicus MGCS10565 heteropolysaccharide repeat unit export protein YP_002123218.1 889636 D 552526 CDS YP_002123219.1 195977975 6762249 890830..892314 1 NC_011134.1 similar to ref|YP_280061.1| hypothetical membrane spanning protein [Streptococcus pyogenes MGAS6180]; hypothetical protein 892314 6762249 Sez_0847 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123219.1 890830 D 552526 CDS YP_002123220.1 195977976 6760910 892328..893491 1 NC_011134.1 similar to ref|ZP_00785358.1| glycosyl transferase, group 1 family protein [Streptococcus agalactiae COH1]; Possibly involved in synthesis of the GCS carbohydrate group antigen.; glycosyl transferase family protein 893491 6760910 Sez_0848 Streptococcus equi subsp. zooepidemicus MGCS10565 glycosyl transferase family protein YP_002123220.1 892328 D 552526 CDS YP_002123221.1 195977977 6762282 893576..895945 1 NC_011134.1 similar to ref|NP_721241.1| hypothetical protein SMU.831 [Streptococcus mutans UA159]; phosphoglycerol transferase 895945 6762282 Sez_0849 Streptococcus equi subsp. zooepidemicus MGCS10565 phosphoglycerol transferase YP_002123221.1 893576 D 552526 CDS YP_002123222.1 195977978 6760911 896013..897032 1 NC_011134.1 similar to ref|ZP_01825231.1| UDP-glucose 4-epimerase [Streptococcus pneumoniae SP11-BS70]; Catalysis of the reaction: UDP-glucose = UDP-galactose.; UDP-glucose 4-epimerase GalE 897032 galE 6760911 galE Streptococcus equi subsp. zooepidemicus MGCS10565 UDP-glucose 4-epimerase GalE YP_002123222.1 896013 D 552526 CDS YP_002123223.1 195977979 6762290 897044..897205 1 NC_011134.1 hypothetical protein 897205 6762290 Sez_0851 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123223.1 897044 D 552526 CDS YP_002123224.1 195977980 6762297 897319..898425 1 NC_011134.1 similar to ref|NP_269015.1| peptidase T [Streptococcus pyogenes M1 GAS]; Releases the N-terminal amino acid from tripeptides. Has a preference for tripeptides containing a N-terminal methionine or leucine.; tripeptide aminopeptidase PepT 898425 pepT 6762297 pepT Streptococcus equi subsp. zooepidemicus MGCS10565 tripeptide aminopeptidase PepT YP_002123224.1 897319 D 552526 CDS YP_002123225.1 195977981 6760915 898516..898959 1 NC_011134.1 similar to ref|YP_059950.1| Gene info Pore forming protein ebsA [Streptococcus pyogenes MGAS10394]; pore-forming peptide EbsA-like 898959 ebsA 6760915 ebsA Streptococcus equi subsp. zooepidemicus MGCS10565 pore-forming peptide EbsA-like YP_002123225.1 898516 D 552526 CDS YP_002123226.1 195977982 6760919 complement(898946..899143) 1 NC_011134.1 similar to ref|NP_269017.1| ferredoxin [Streptococcus pyogenes M1 GAS]; ferredoxin 899143 6760919 Sez_0854 Streptococcus equi subsp. zooepidemicus MGCS10565 ferredoxin YP_002123226.1 898946 R 552526 CDS YP_002123227.1 195977983 6760918 899192..899701 1 NC_011134.1 similar to ref|YP_280065.1| hypothetical membrane associated protein [Streptococcus pyogenes MGAS6180]; hypothetical protein 899701 6760918 Sez_0855 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123227.1 899192 D 552526 CDS YP_002123228.1 195977984 6762295 899716..900396 1 NC_011134.1 Catalyzes the formation of (d)CDP from ATP and (d)CMP; cytidylate kinase 900396 cmk 6762295 cmk Streptococcus equi subsp. zooepidemicus MGCS10565 cytidylate kinase YP_002123228.1 899716 D 552526 CDS YP_002123229.1 195977985 6762184 900557..901087 1 NC_011134.1 IF-3 has several functions that are required and promote translation initiation including; preventing association of 70S by binding to 30S; monitoring codon-anticodon interactions by promoting disassociation of fMet-tRNA(fMet) from initiation complexes formed on leaderless mRNAs or incorrectly bound noninitiatior tRNAs and complexes with noncanonical start sites; stimulates codon-anticodon interactions at P-site; involved in moving mRNA to the P-site; and in recycling subunits; translation initiation factor IF-3 901087 infC 6762184 infC Streptococcus equi subsp. zooepidemicus MGCS10565 translation initiation factor IF-3 YP_002123229.1 900557 D 552526 CDS YP_002123230.1 195977986 6760923 901127..901324 1 NC_011134.1 similar to ref|YP_001035443.1| 50S ribosomal protein L35 [Streptococcus sanguinis SK36]; 50S ribosomal protein L35 901324 rpmI 6760923 rpmI Streptococcus equi subsp. zooepidemicus MGCS10565 50S ribosomal protein L35 YP_002123230.1 901127 D 552526 CDS YP_002123231.1 195977987 6760926 901385..901744 1 NC_011134.1 binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit; 50S ribosomal protein L20 901744 rplT 6760926 rplT Streptococcus equi subsp. zooepidemicus MGCS10565 50S ribosomal protein L20 YP_002123231.1 901385 D 552526 CDS YP_002123232.1 195977988 6762266 901893..902048 1 NC_011134.1 hypothetical protein 902048 6762266 Sez_0860 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123232.1 901893 D 552526 CDS YP_002123233.1 195977989 6760925 902379..903056 1 NC_011134.1 similar to ref|YP_848744.1| secreted MUCin-binding domain protein [Listeria welshimeri serovar 6b str. SLCC5334]; Unknown, possibly involved in mucin-binding.; cell wall surface anchor family protein 903056 6760925 Sez_0861 Streptococcus equi subsp. zooepidemicus MGCS10565 cell wall surface anchor family protein YP_002123233.1 902379 D 552526 CDS YP_002123234.1 195977990 6760929 complement(903168..905354) 1 NC_011134.1 similar to ref|YP_602203.1| Sulfatase family protein [Streptococcus pyogenes MGAS10750]; phosphoglycerol transferase 905354 6760929 Sez_0862 Streptococcus equi subsp. zooepidemicus MGCS10565 phosphoglycerol transferase YP_002123234.1 903168 R 552526 CDS YP_002123235.1 195977991 6760922 905502..906665 1 NC_011134.1 similar to ref|YP_281986.1| methyltransferase [Streptococcus pyogenes MGAS5005]; SAM-dependent methyltransferase 906665 6760922 Sez_0863 Streptococcus equi subsp. zooepidemicus MGCS10565 SAM-dependent methyltransferase YP_002123235.1 905502 D 552526 CDS YP_002123236.1 195977992 6762304 906662..907342 1 NC_011134.1 catalyzes the dehydration of 3-dehydroquinate to form 3-dehydroshikimate in aromatic amino acid biosynthesis; 3-dehydroquinate dehydratase 907342 aroD 6762304 aroD Streptococcus equi subsp. zooepidemicus MGCS10565 3-dehydroquinate dehydratase YP_002123236.1 906662 D 552526 CDS YP_002123237.1 195977993 6760933 907455..908621 1 NC_011134.1 catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis; chorismate synthase 908621 aroC 6760933 aroC Streptococcus equi subsp. zooepidemicus MGCS10565 chorismate synthase YP_002123237.1 907455 D 552526 CDS YP_002123238.1 195977994 6760927 908682..909023 1 NC_011134.1 similar to ref|YP_059961.1| Hypothetical cytosolic protein [Streptococcus pyogenes MGAS10394]; hypothetical protein 909023 6760927 Sez_0866 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123238.1 908682 D 552526 CDS YP_002123239.1 195977995 6762278 909217..910569 1 NC_011134.1 catalyzes the reduction of 2 glutathione to glutathione disulfide; maintains high levels of reduced glutathione in the cytosol; involved in redox regulation and oxidative defense; glutathione reductase 910569 6762278 Sez_0867 Streptococcus equi subsp. zooepidemicus MGCS10565 glutathione reductase YP_002123239.1 909217 D 552526 CDS YP_002123240.1 195977996 6762230 complement(910640..911080) 1 NC_011134.1 similar to ref|NP_607031.1| hypothetical protein spyM18_0877 [Streptococcus pyogenes MGAS8232]; hypothetical protein 911080 6762230 Sez_0868 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123240.1 910640 R 552526 CDS YP_002123241.1 195977997 6760930 911320..912462 1 NC_011134.1 similar to ref|YP_598295.1| Cysteine desulfurase / Selenocysteine lyase [Streptococcus pyogenes MGAS10270]; Fe-S cluster biosynthesis.; cysteine desulfurase 912462 iscS 6760930 iscS Streptococcus equi subsp. zooepidemicus MGCS10565 cysteine desulfurase YP_002123241.1 911320 D 552526 CDS YP_002123242.1 195977998 6762316 912482..913678 1 NC_011134.1 Required for the synthesis of the thiazole moiety; thiamine biosynthesis protein ThiI 913678 thiI 6762316 thiI Streptococcus equi subsp. zooepidemicus MGCS10565 thiamine biosynthesis protein ThiI YP_002123242.1 912482 D 552526 CDS YP_002123243.1 195977999 6760935 complement(913802..913993) 1 NC_011134.1 hypothetical protein 913993 6760935 Sez_0871 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123243.1 913802 R 552526 CDS YP_002123244.1 195978000 6762323 complement(914376..915425) 1 NC_011134.1 similar to gb|ABH04315.1| IgG endopeptidase [Streptococcus equi subsp. zooepidemicus]; IgG cleavage resistance to the host immune response.; IgG-degrading enzyme/Mac-1 IdeZ 915425 ideZ 6762323 ideZ Streptococcus equi subsp. zooepidemicus MGCS10565 IgG-degrading enzyme/Mac-1 IdeZ YP_002123244.1 914376 R 552526 CDS YP_002123245.1 195978001 6762301 complement(915949..916311) 1 NC_011134.1 hypothetical protein 916311 6762301 Sez_0874 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123245.1 915949 R 552526 CDS YP_002123246.1 195978002 6761194 complement(917276..918406) 1 NC_011134.1 similar to ref|YP_596508.1| transposase [Streptococcus pyogenes MGAS9429]; transposase IS1548-like 918406 6761194 Sez_0875 Streptococcus equi subsp. zooepidemicus MGCS10565 transposase IS1548-like YP_002123246.1 917276 R 552526 CDS YP_002123247.1 195978003 6760941 918483..919118 1 NC_011134.1 similar to ref|YP_060299.1| membrane-associated alkaline phosphatase [Streptococcus pyogenes MGAS10394]; hypothetical protein 919118 6760941 Sez_0876 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123247.1 918483 D 552526 CDS YP_002123248.1 195978004 6760908 complement(919165..919959) 1 NC_011134.1 similar to ref|ZP_00365831.1| COG0477: Permeases of the major facilitator superfamily [Streptococcus pyogenes M49 591]; ABC transporter permease 919959 6760908 Sez_0877 Streptococcus equi subsp. zooepidemicus MGCS10565 ABC transporter permease YP_002123248.1 919165 R 552526 CDS YP_002123249.1 195978005 6760939 complement(919969..920667) 1 NC_011134.1 similar to ref|ZP_00365454.1| COG1131: ABC-type multidrug transport system, ATPase component [Streptococcus pyogenes M49 591]; ABC transporter ATP-binding protein 920667 6760939 Sez_0878 Streptococcus equi subsp. zooepidemicus MGCS10565 ABC transporter ATP-binding protein YP_002123249.1 919969 R 552526 CDS YP_002123250.1 195978006 6760952 complement(920667..921038) 1 NC_011134.1 similar to ref|YP_600647.1| Transcriptional regulator, GntR family [Streptococcus pyogenes MGAS2096]; GntR family transcriptional regulator 921038 6760952 Sez_0879 Streptococcus equi subsp. zooepidemicus MGCS10565 GntR family transcriptional regulator YP_002123250.1 920667 R 552526 CDS YP_002123251.1 195978007 6760948 921250..924390 1 NC_011134.1 Catalyzes DNA-template-directed extension of the 3'-end of a DNA strand by one nucleotide at a time. Proposed to be responsible for the synthesis of the lagging strand. In the low GC gram positive bacteria this enzyme is less processive and more error prone than its counterpart in other bacteria.; DNA polymerase III DnaE 924390 dnaE 6760948 dnaE Streptococcus equi subsp. zooepidemicus MGCS10565 DNA polymerase III DnaE YP_002123251.1 921250 D 552526 CDS YP_002123252.1 195978008 6760945 924470..925483 1 NC_011134.1 catalyzes the formation of D-fructose 1,6-bisphosphate from D-fructose 6-phosphate in glycolysis; 6-phosphofructokinase 925483 pfkA 6760945 pfkA Streptococcus equi subsp. zooepidemicus MGCS10565 6-phosphofructokinase YP_002123252.1 924470 D 552526 CDS YP_002123253.1 195978009 6760946 925545..927047 1 NC_011134.1 catalyzes the formation of phosphoenolpyruvate from pyruvate; pyruvate kinase 927047 pyk 6760946 pyk Streptococcus equi subsp. zooepidemicus MGCS10565 pyruvate kinase YP_002123253.1 925545 D 552526 CDS YP_002123254.1 195978010 6762350 927176..927733 1 NC_011134.1 similar to ref|YP_280427.1| signal peptidase I [Streptococcus pyogenes MGAS6180]; signal peptidase I LepB 927733 lepB 6762350 lepB Streptococcus equi subsp. zooepidemicus MGCS10565 signal peptidase I LepB YP_002123254.1 927176 D 552526 CDS YP_002123255.1 195978011 6760954 927910..929721 1 NC_011134.1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source; glucosamine--fructose-6-phosphate aminotransferase 929721 glmS 6760954 glmS Streptococcus equi subsp. zooepidemicus MGCS10565 glucosamine--fructose-6-phosphate aminotransferase YP_002123255.1 927910 D 552526 CDS YP_002123256.1 195978012 6760956 929905..930240 1 NC_011134.1 similar to ref|NP_607338.1| hypothetical protein spyM18_1226 [Streptococcus pyogenes MGAS8232]; Unknown, The PhnA protein family includes the uncharacterised Escherichia coli protein PhnA and its homologues. The E. coli phnA gene is part of a large operon associated with alkylphosphonate uptake and carbon-phosphorus bond cleavage. The protein is not related to the characterised phosphonoacetate hydrolase designated PhnA.; PhnA protein 930240 phnA 6760956 phnA Streptococcus equi subsp. zooepidemicus MGCS10565 PhnA protein YP_002123256.1 929905 D 552526 CDS YP_002123257.1 195978013 6762232 930359..930988 1 NC_011134.1 similar to ref|YP_602628.1| Histidine transport system permease HisM [Streptococcus pyogenes MGAS10750]; Probably part of a binding-protein-dependent transport system for an amino acid. Probably responsible for the translocation of the substrate across the membrane.; amino acid ABC transporter membrane-spanning permease 930988 6762232 Sez_0886 Streptococcus equi subsp. zooepidemicus MGCS10565 amino acid ABC transporter membrane-spanning permease YP_002123257.1 930359 D 552526 CDS YP_002123258.1 195978014 6762161 930998..931627 1 NC_011134.1 similar to ref|YP_602627.1| Histidine transport ATP-binding protein hisP [Streptococcus pyogenes MGAS10750]; Part of the binding-protein-dependent transport system for histidine. Probably responsible for energy coupling to the transport system.; amino acid transport ATP-binding protein 931627 6762161 Sez_0887 Streptococcus equi subsp. zooepidemicus MGCS10565 amino acid transport ATP-binding protein YP_002123258.1 930998 D 552526 CDS YP_002123259.1 195978015 6762178 931644..932480 1 NC_011134.1 similar to gb|AAC35851.1| amino acid-binding protein Abp [Streptococcus uberis]; Probably part of a binding-protein-dependent transport system for an amino acid.; amino acid ABC transporter substrate-binding protein 932480 6762178 Sez_0888 Streptococcus equi subsp. zooepidemicus MGCS10565 amino acid ABC transporter substrate-binding protein YP_002123259.1 931644 D 552526 CDS YP_002123260.1 195978016 6762183 complement(932591..933829) 1 NC_011134.1 similar to ref|YP_598703.1| Cobalt-zinc-cadmium resistance protein czcD [Streptococcus pyogenes MGAS10270]; cation efflux family protein 933829 6762183 Sez_0889 Streptococcus equi subsp. zooepidemicus MGCS10565 cation efflux family protein YP_002123260.1 932591 R 552526 CDS YP_002123261.1 195978017 6762235 complement(933932..935266) 1 NC_011134.1 similar to ref|YP_060286.1| Na(+)-linked D-alanine glycine permease [Streptococcus pyogenes MGAS10394]; Na(+)-linked D-alanine glycine permease 935266 6762235 Sez_0890 Streptococcus equi subsp. zooepidemicus MGCS10565 Na(+)-linked D-alanine glycine permease YP_002123261.1 933932 R 552526 CDS YP_002123262.1 195978018 6762105 935746..938043 1 NC_011134.1 similar to ref|YP_060284.1| DNA helicase II [Streptococcus pyogenes MGAS10394]; Essential helicase; ATP-dependent DNA helicase UvrD 938043 pcrA 6762105 pcrA Streptococcus equi subsp. zooepidemicus MGCS10565 ATP-dependent DNA helicase UvrD YP_002123262.1 935746 D 552526 CDS YP_002123263.1 195978019 6762069 938434..938694 1 NC_011134.1 similar to ref|NP_269398.1| hypothetical protein SPy_1265 [Streptococcus pyogenes M1 GAS]; hypothetical protein 938694 6762069 Sez_0892 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123263.1 938434 D 552526 CDS YP_002123264.1 195978020 6762046 938742..939323 1 NC_011134.1 similar to ref|NP_607329.1| hypothetical protein spyM18_1215 [Streptococcus pyogenes MGAS8232]; hypothetical protein 939323 6762046 Sez_0893 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123264.1 938742 D 552526 CDS YP_002123265.1 195978021 6762021 939333..939521 1 NC_011134.1 similar to ref|YP_001128385.1| hypothetical protein SpyM50826 [Streptococcus pyogenes str. Manfredo]; hypothetical protein 939521 6762021 Sez_0894 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123265.1 939333 D 552526 CDS YP_002123266.1 195978022 6761963 939534..940073 1 NC_011134.1 similar to ref|YP_280413.1| general stress protein, Gls24 family [Streptococcus pyogenes MGAS6180]; hypothetical protein 940073 6761963 Sez_0895 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123266.1 939534 D 552526 CDS YP_002123267.1 195978023 6761821 940024..940230 1 NC_011134.1 similar to ref|YP_596806.1| hypothetical protein MGAS9429_Spy1075 [Streptococcus pyogenes MGAS9429]; hypothetical protein 940230 6761821 Sez_0896 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123267.1 940024 D 552526 CDS YP_002123268.1 195978024 6761847 940240..940728 1 NC_011134.1 similar to ref|YP_280411.1| general stress protein, Gls24 family [Streptococcus pyogenes MGAS6180]; hypothetical protein 940728 6761847 Sez_0897 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123268.1 940240 D 552526 CDS YP_002123269.1 195978025 6761839 940886..941527 1 NC_011134.1 similar to ref|YP_598693.1| NAD-dependent K+ or Na+ uptake system component / Transcriptional regulator, GntR family [Streptococcus pyogenes MGAS10270]; transcriptional regulator 941527 6761839 Sez_0898 Streptococcus equi subsp. zooepidemicus MGCS10565 transcriptional regulator YP_002123269.1 940886 D 552526 CDS YP_002123270.1 195978026 6761844 complement(941644..942192) 1 NC_011134.1 similar to ref|YP_598691.1| Transcriptional regulator, TetR family [Streptococcus pyogenes MGAS10270]; TetR family transcriptional regulator 942192 6761844 Sez_0899 Streptococcus equi subsp. zooepidemicus MGCS10565 TetR family transcriptional regulator YP_002123270.1 941644 R 552526 CDS YP_002123271.1 195978027 6761712 942315..943016 1 NC_011134.1 similar to ref|NP_269390.1| ABC transporter (ATP-binding protein) [Streptococcus pyogenes M1 GAS]; ABC transporter ATP-binding protein 943016 6761712 Sez_0900 Streptococcus equi subsp. zooepidemicus MGCS10565 ABC transporter ATP-binding protein YP_002123271.1 942315 D 552526 CDS YP_002123272.1 195978028 6761722 943028..945667 1 NC_011134.1 similar to ref|YP_596800.1| ABC transporter permease [Streptococcus pyogenes MGAS9429]; ABC transporter permease 945667 6761722 Sez_0901 Streptococcus equi subsp. zooepidemicus MGCS10565 ABC transporter permease YP_002123272.1 943028 D 552526 CDS YP_002123273.1 195978029 6761721 945743..946339 1 NC_011134.1 similar to ref|YP_060272.1| Type I restriction-modification system specificity subunit [Streptococcus pyogenes MGAS10394]; type I restriction- system specificity subunit 946339 6761721 Sez_0902 Streptococcus equi subsp. zooepidemicus MGCS10565 type I restriction- system specificity subunit YP_002123273.1 945743 D 552526 CDS YP_002123274.1 195978030 6761645 946349..947311 1 NC_011134.1 similar to ref|YP_602608.1| Integral membrane protein [Streptococcus pyogenes MGAS10750]; hypothetical protein 947311 6761645 Sez_0903 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123274.1 946349 D 552526 CDS YP_002123275.1 195978031 6761590 947408..948745 1 NC_011134.1 similar to ref|YP_001128395.1| hypothetical protein SpyM50836 [Streptococcus pyogenes str. Manfredo]; hypothetical protein 948745 6761590 Sez_0904 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123275.1 947408 D 552526 CDS YP_002123276.1 195978032 6761464 948854..949735 1 NC_011134.1 catalyzes isomerization of specific uridines in RNA to pseudouridine; responsible for residues in T loops of many tRNAs; tRNA pseudouridine synthase B 949735 truB 6761464 truB Streptococcus equi subsp. zooepidemicus MGCS10565 tRNA pseudouridine synthase B YP_002123276.1 948854 D 552526 CDS YP_002123277.1 195978033 6761505 949749..950681 1 NC_011134.1 catalyzes the formation of FMN from riboflavin and the formation of FAD from FMN; in Bacillus the ribC gene has both flavokinase and FAD synthetase activities; bifunctional riboflavin kinase/FMN adenylyltransferase 950681 ribC 6761505 ribC Streptococcus equi subsp. zooepidemicus MGCS10565 bifunctional riboflavin kinase/FMN adenylyltransferase YP_002123277.1 949749 D 552526 CDS YP_002123278.1 195978034 6761443 950724..951128 1 NC_011134.1 the anti-alpha factor Spx interacts with RNA polymerase alpha subunit C-terminal domain in a region that interacts with the sigma 70 subunit and may interfere with activation of promoters; in Bacillus subtilis this protein is a substrate for ClpXP protease; blocks transcription of the competence regulatory gene encoded by the srf operon; regulates a number of genes involved in thiol homeostasis including trxA and trxB; monomeric member of ArsC family of proteins; does not bind DNA; contains a disulfide bond between C10 and C13 which may sense disulfide stress; transcriptional regulator Spx 951128 spxA 6761443 spxA Streptococcus equi subsp. zooepidemicus MGCS10565 transcriptional regulator Spx YP_002123278.1 950724 D 552526 CDS YP_002123279.1 195978035 6761440 951130..951408 1 NC_011134.1 similar to ref|YP_060266.1| hypothetical protein M6_Spy0948 [Streptococcus pyogenes MGAS10394]; hypothetical protein 951408 6761440 Sez_0908 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123279.1 951130 D 552526 CDS YP_002123280.1 195978036 6761438 951398..952174 1 NC_011134.1 similar to ref|YP_060265.1| Myo-inositol-1(or 4)-monophosphatase [Streptococcus pyogenes MGAS10394]; Catalysis of the reaction: myo-inositol 1-phosphate + H2O = myo-inositol + phosphate.; myo-inositol-1(or 4)-monophosphatase 952174 6761438 Sez_0909 Streptococcus equi subsp. zooepidemicus MGCS10565 myo-inositol-1(or 4)-monophosphatase YP_002123280.1 951398 D 552526 CDS YP_002123281.1 195978037 6761414 952182..953498 1 NC_011134.1 similar to ref|YP_596791.1| 23S rRNA m(5)C methyltransferase [Streptococcus pyogenes MGAS9429]; tRNA and rRNA cytosine-C5-methylases 953498 6761414 Sez_0910 Streptococcus equi subsp. zooepidemicus MGCS10565 tRNA and rRNA cytosine-C5-methylases YP_002123281.1 952182 D 552526 CDS YP_002123282.1 195978038 6761345 953636..954502 1 NC_011134.1 similar to ref|NP_664685.1| phosphate ABC transporter, periplasmic phosphate-binding protein [Streptococcus pyogenes MGAS315]; Probably part of the binding-protein-dependent transport system.; ABC transporter binding protein 954502 6761345 Sez_0911 Streptococcus equi subsp. zooepidemicus MGCS10565 ABC transporter binding protein YP_002123282.1 953636 D 552526 CDS YP_002123283.1 195978039 6761381 954513..955448 1 NC_011134.1 similar to ref|YP_598678.1| Phosphate transport system permease pstC [Streptococcus pyogenes MGAS10270]; phosphate ABC transporter permease 955448 ptsC 6761381 ptsC Streptococcus equi subsp. zooepidemicus MGCS10565 phosphate ABC transporter permease YP_002123283.1 954513 D 552526 CDS YP_002123284.1 195978040 6761359 955438..956325 1 NC_011134.1 similar to ref|NP_607308.1| phosphate ABC transporter (permease) [Streptococcus pyogenes MGAS8232]; phosphate ABC transporter permease 956325 ptsA 6761359 ptsA Streptococcus equi subsp. zooepidemicus MGCS10565 phosphate ABC transporter permease YP_002123284.1 955438 D 552526 CDS YP_002123285.1 195978041 6760871 956342..957145 1 NC_011134.1 ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation; phosphate transporter ATP-binding protein 957145 pstB2 6760871 pstB2 Streptococcus equi subsp. zooepidemicus MGCS10565 phosphate transporter ATP-binding protein YP_002123285.1 956342 D 552526 CDS YP_002123286.1 195978042 6760869 957156..957917 1 NC_011134.1 ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation; phosphate transporter ATP-binding protein 957917 pstB1 6760869 pstB1 Streptococcus equi subsp. zooepidemicus MGCS10565 phosphate transporter ATP-binding protein YP_002123286.1 957156 D 552526 CDS YP_002123287.1 195978043 6760867 957988..958641 1 NC_011134.1 similar to ref|NP_607305.1| phosphate uptake regulatory protein [Streptococcus pyogenes MGAS8232]; Not known; probably involved in phosphate transport and/or metabolism.; phosphate transport system protein PhoU 958641 phoU 6760867 phoU Streptococcus equi subsp. zooepidemicus MGCS10565 phosphate transport system protein PhoU YP_002123287.1 957988 D 552526 CDS YP_002123288.1 195978044 6760865 958875..961412 1 NC_011134.1 similar to ref|YP_598672.1| Lysyl aminopeptidase / alanine aminopeptidase [Streptococcus pyogenes MGAS10270]; Aminopeptidase with broad substrate specificity to several peptides. It has more affinity for oligopeptides than for dipeptides. It plays an essential role in the metabolism, it may be involved in nitrogen supply or protein turnover.; aminopeptidase 961412 pepN 6760865 pepN Streptococcus equi subsp. zooepidemicus MGCS10565 aminopeptidase YP_002123288.1 958875 D 552526 CDS YP_002123289.1 195978045 6760863 961517..961642 1 NC_011134.1 hypothetical protein 961642 6760863 Sez_0918 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123289.1 961517 D 552526 CDS YP_002123290.1 195978046 6760861 961839..962513 1 NC_011134.1 similar to ref|YP_060255.1| CiaR [Streptococcus pyogenes MGAS10394]; Member of the two-component regulatory system ciaH/ciaR. Involved in early steps of competence regulation and in penicillin susceptibility.; TCS transcriptional regulatory protein ciaR 962513 ciaR 6760861 ciaR Streptococcus equi subsp. zooepidemicus MGCS10565 TCS transcriptional regulatory protein ciaR YP_002123290.1 961839 D 552526 CDS YP_002123291.1 195978047 6760856 962506..963816 1 NC_011134.1 similar to ref|YP_060254.1| CiaH [Streptococcus pyogenes MGAS10394]; Member of the two-component regulatory system ciaH/ciaR. Involved in early steps of competence regulation and in penicillin susceptibility. Probably phosphorylates ciaR.; TCS sensor kinase ciaH 963816 ciaH 6760856 ciaH Streptococcus equi subsp. zooepidemicus MGCS10565 TCS sensor kinase ciaH YP_002123291.1 962506 D 552526 CDS YP_002123292.1 195978048 6760854 964202..964633 1 NC_011134.1 similar to ref|YP_849450.1| hypothetical protein [Listeria welshimeri serovar 6b str. SLCC5334]; hypothetical protein 964633 6760854 Sez_0921 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123292.1 964202 D 552526 CDS YP_002123293.1 195978049 6760851 964715..964891 1 NC_011134.1 hypothetical protein 964891 6760851 Sez_0922 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123293.1 964715 D 552526 CDS YP_002123294.1 195978050 6760847 965064..965447 1 NC_011134.1 similar to ref|NP_734694.1| Gene info hypothetical protein gbs0224 [Streptococcus agalactiae NEM316]; hypothetical protein 965447 6760847 Sez_0923 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123294.1 965064 D 552526 CDS YP_002123295.1 195978051 6760845 965444..965704 1 NC_011134.1 similar to ref|YP_849451.1| hypothetical protein lwe1254 [Listeria welshimeri serovar 6b str. SLCC5334]; hypothetical protein 965704 6760845 Sez_0924 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123295.1 965444 D 552526 CDS YP_002123296.1 195978052 6760842 965720..966133 1 NC_011134.1 similar to ref|NP_736409.1| hypothetical protein gbs1976 [Streptococcus agalactiae NEM316]; hypothetical protein 966133 6760842 Sez_0925 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123296.1 965720 D 552526 CDS YP_002123297.1 195978053 6760840 966348..966743 1 NC_011134.1 similar to ref|ZP_00874490.1| hypothetical protein SsuiDRAFT_1547 [Streptococcus suis 89/1591]; hypothetical protein 966743 6760840 Sez_0926 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123297.1 966348 D 552526 CDS YP_002123298.1 195978054 6760838 966743..967936 1 NC_011134.1 similar to ref|NP_736400.1| hypothetical protein gbs1967 [Streptococcus agalactiae NEM316]; hypothetical protein 967936 6760838 Sez_0927 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123298.1 966743 D 552526 CDS YP_002123299.1 195978055 6760836 967933..968325 1 NC_011134.1 similar to ref|ZP_00874484.1| hypothetical protein SsuiDRAFT_1541 [Streptococcus suis 89/1591]; hypothetical protein 968325 6760836 Sez_0928 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123299.1 967933 D 552526 CDS YP_002123300.1 195978056 6760832 968344..968628 1 NC_011134.1 similar to ref|ZP_00785752.1| Unknown [Streptococcus agalactiae COH1]; hypothetical protein 968628 6760832 Sez_0929 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123300.1 968344 D 552526 CDS YP_002123301.1 195978057 6760830 complement(968841..969083) 1 NC_011134.1 binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase; 30S ribosomal protein S20 969083 rpsT 6760830 rpsT Streptococcus equi subsp. zooepidemicus MGCS10565 30S ribosomal protein S20 YP_002123301.1 968841 R 552526 CDS YP_002123302.1 195978058 6760828 complement(969143..970063) 1 NC_011134.1 catalyzes the formation of (R)-4'-phosphopantothenate in coenzyme A biosynthesis; pantothenate kinase 970063 coaA 6760828 coaA Streptococcus equi subsp. zooepidemicus MGCS10565 pantothenate kinase YP_002123302.1 969143 R 552526 CDS YP_002123303.1 195978059 6760826 970298..970927 1 NC_011134.1 similar to ref|YP_598667.1| 16S rRNA m(2)G 1207 methyltransferase [Streptococcus pyogenes MGAS10270]; Specifically methylates the guanosine in position 1207 of 16s rRNA in the 30s particle.; 16S rRNA m(2)G 1207 methyltransferase 970927 6760826 Sez_0932 Streptococcus equi subsp. zooepidemicus MGCS10565 16S rRNA m(2)G 1207 methyltransferase YP_002123303.1 970298 D 552526 CDS YP_002123304.1 195978060 6760822 971026..972303 1 NC_011134.1 Catalyzes the reversible phosphorolysis of pyrimidines in the nucleotide synthesis salvage pathway; pyrimidine-nucleoside phosphorylase 972303 pdp 6760822 pdp Streptococcus equi subsp. zooepidemicus MGCS10565 pyrimidine-nucleoside phosphorylase YP_002123304.1 971026 D 552526 CDS YP_002123305.1 195978061 6760820 972317..972979 1 NC_011134.1 catalyzes the formation of D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-D-ribose-5-phosphate; deoxyribose-phosphate aldolase 972979 deoC 6760820 deoC Streptococcus equi subsp. zooepidemicus MGCS10565 deoxyribose-phosphate aldolase YP_002123305.1 972317 D 552526 CDS YP_002123306.1 195978062 6760817 972966..973355 1 NC_011134.1 Reclaims exogenous and endogenous cytidine and 2'-deoxycytidine molecules for UMP synthesis; cytidine deaminase 973355 cdd 6760817 cdd Streptococcus equi subsp. zooepidemicus MGCS10565 cytidine deaminase YP_002123306.1 972966 D 552526 CDS YP_002123307.1 195978063 6760813 973446..974498 1 NC_011134.1 similar to ref|YP_280382.1| nucleoside-binding protein [Streptococcus pyogenes MGAS6180]; ABC transporter substrate-binding lipoprotein 974498 6760813 Sez_0936 Streptococcus equi subsp. zooepidemicus MGCS10565 ABC transporter substrate-binding lipoprotein YP_002123307.1 973446 D 552526 CDS YP_002123308.1 195978064 6760811 974625..976157 1 NC_011134.1 similar to ref|ZP_00365738.1| COG3845: ABC-type uncharacterized transport systems, ATPase components [Streptococcus pyogenes M49 591]; Part of the binding-protein-dependent transport system for nucleosides. Probably responsible for energy coupling to the transport system.; nucleoside transport ATP-binding protein 976157 6760811 Sez_0937 Streptococcus equi subsp. zooepidemicus MGCS10565 nucleoside transport ATP-binding protein YP_002123308.1 974625 D 552526 CDS YP_002123309.1 195978065 6760809 976150..977214 1 NC_011134.1 similar to ref|YP_280380.1| nucleoside transport system permease [Streptococcus pyogenes MGAS6180]; ABC transporter permease 977214 6760809 Sez_0938 Streptococcus equi subsp. zooepidemicus MGCS10565 ABC transporter permease YP_002123309.1 976150 D 552526 CDS YP_002123310.1 195978066 6760804 977216..978172 1 NC_011134.1 similar to ref|YP_060246.1| Nucleoside transport system permease [Streptococcus pyogenes MGAS10394]; ABC transporter permease 978172 6760804 Sez_0939 Streptococcus equi subsp. zooepidemicus MGCS10565 ABC transporter permease YP_002123310.1 977216 D 552526 CDS YP_002123311.1 195978067 6760802 complement(978210..978332) 1 NC_011134.1 hypothetical protein 978332 6760802 Sez_0940 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123311.1 978210 R 552526 CDS YP_002123312.1 195978068 6760800 complement(978605..980353) 1 NC_011134.1 similar to ref|YP_001128419.1| phosphomannomutase [Streptococcus pyogenes str. Manfredo]; phosphomannomutase 980353 pgmA 6760800 pgmA Streptococcus equi subsp. zooepidemicus MGCS10565 phosphomannomutase YP_002123312.1 978605 R 552526 CDS YP_002123313.1 195978069 6760798 complement(980499..981071) 1 NC_011134.1 similar to ref|YP_280377.1| transporter [Streptococcus pyogenes MGAS6180]; pantothenate transporter 981071 6760798 Sez_0942 Streptococcus equi subsp. zooepidemicus MGCS10565 pantothenate transporter YP_002123313.1 980499 R 552526 CDS YP_002123314.1 195978070 6760796 complement(981127..981672) 1 NC_011134.1 decarboxylates 4-phosphopantothenoylcysteine to form 4'-phosphopantotheine.; phosphopantothenoylcysteine decarboxylase 981672 coaC 6760796 coaC Streptococcus equi subsp. zooepidemicus MGCS10565 phosphopantothenoylcysteine decarboxylase YP_002123314.1 981127 R 552526 CDS YP_002123315.1 195978071 6760794 complement(981665..982357) 1 NC_011134.1 similar to ref|YP_596769.1| phosphopantothenate--cysteine ligase [Streptococcus pyogenes MGAS9429]; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.; phosphopantothenate--cysteine ligase 982357 coaBC 6760794 coaBC Streptococcus equi subsp. zooepidemicus MGCS10565 phosphopantothenate--cysteine ligase YP_002123315.1 981665 R 552526 CDS YP_002123316.1 195978072 6760791 982555..984225 1 NC_011134.1 catalyzes the formation of 10-formyltetrahydrofolate from formate and tetrahydrofolate; formate--tetrahydrofolate ligase 984225 fhs1 6760791 fhs1 Streptococcus equi subsp. zooepidemicus MGCS10565 formate--tetrahydrofolate ligase YP_002123316.1 982555 D 552526 CDS YP_002123317.1 195978073 6760789 984524..987895 1 NC_011134.1 similar to ref|ZP_00781360.1| streptococcal C5a peptidase [Streptococcus agalactiae 18RS21]; This virulence factor of S.pyogenes specifically cleaves the human serum chemotaxin C5a at 68-Lys-|-Asp-69 bond near its C- terminus, destroying its ability to serve as a chemoattractant, in GAS it sets in the MGA regulon.; C5a peptidase precursor ScpZ 987895 scpZ 6760789 scpZ Streptococcus equi subsp. zooepidemicus MGCS10565 C5a peptidase precursor ScpZ YP_002123317.1 984524 D 552526 CDS YP_002123318.1 195978074 6760787 988019..989686 1 NC_011134.1 similar to ref|NP_607281.1| cardiolipin synthetase [Streptococcus pyogenes MGAS8232]; Catalyzes The Reversible Phosphatidyl Group Transfer From One Phosphatidylglycerol Molecule To Another To Form Cardiolipin (Cl) (Diphosphatidylglycerol) And Glycerol. Affects Resistance To The Gyrase Inhibitor Novobiocin.; cardiolipin synthetase Cls 989686 cls 6760787 cls Streptococcus equi subsp. zooepidemicus MGCS10565 cardiolipin synthetase Cls YP_002123318.1 988019 D 552526 CDS YP_002123319.1 195978075 6760784 990103..991191 1 NC_011134.1 catalyzes the formation of 4-aspartyl phosphate from aspartate 4-semialdehyde; aspartate-semialdehyde dehydrogenase 991191 asd 6760784 asd Streptococcus equi subsp. zooepidemicus MGCS10565 aspartate-semialdehyde dehydrogenase YP_002123319.1 990103 D 552526 CDS YP_002123320.1 195978076 6760782 991291..991629 1 NC_011134.1 similar to ref|NP_664655.1| anaerobic ribonucleotide reductase [Streptococcus pyogenes MGAS315]; anaerobic ribonucleoside triphosphate reductase NrdD 991629 nrdD 6760782 nrdD Streptococcus equi subsp. zooepidemicus MGCS10565 anaerobic ribonucleoside triphosphate reductase NrdD YP_002123320.1 991291 D 552526 CDS YP_002123321.1 195978077 6760779 complement(991665..992948) 1 NC_011134.1 similar to ref|YP_001128433.1| GntR family regulatory protein [Streptococcus pyogenes str. Manfredo]; GntR family transcriptional regulator 992948 6760779 Sez_0950 Streptococcus equi subsp. zooepidemicus MGCS10565 GntR family transcriptional regulator YP_002123321.1 991665 R 552526 CDS YP_002123322.1 195978078 6760776 993028..993897 1 NC_011134.1 catalyzes the formation of pyridoxal 5'-phosphate from pyridoxal; pyridoxamine kinase 993897 6760776 Sez_0951 Streptococcus equi subsp. zooepidemicus MGCS10565 pyridoxamine kinase YP_002123322.1 993028 D 552526 CDS YP_002123323.1 195978079 6760774 993890..994435 1 NC_011134.1 similar to emb|CAM30204.1| membrane protein [Streptococcus pyogenes str. Manfredo]; hypothetical protein 994435 6760774 Sez_0952 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123323.1 993890 D 552526 CDS YP_002123324.1 195978080 6760772 complement(994912..995061) 1 NC_011134.1 hypothetical protein 995061 6760772 Sez_0953 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123324.1 994912 R 552526 CDS YP_002123325.1 195978081 6760770 995070..996656 1 NC_011134.1 similar to ref|YP_280361.1| ABC transporter ATP-binding protein [Streptococcus pyogenes MGAS6180]; ABC transporter 996656 6760770 Sez_0954 Streptococcus equi subsp. zooepidemicus MGCS10565 ABC transporter YP_002123325.1 995070 D 552526 CDS YP_002123326.1 195978082 6760768 997096..998049 1 NC_011134.1 similar to ref|YP_138591.1| IS1239 transposase [Streptococcus thermophilus LMG 18311]; transposase IS1239 998049 6760768 Sez_0955 Streptococcus equi subsp. zooepidemicus MGCS10565 transposase IS1239 YP_002123326.1 997096 D 552526 CDS YP_002123327.1 195978083 6760766 998162..998419 1 NC_011134.1 similar to ref|YP_596727.1| hypothetical protein MGAS9429_Spy0996 [Streptococcus pyogenes MGAS9429]; hypothetical protein 998419 6760766 Sez_0956 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123327.1 998162 D 552526 CDS YP_002123328.1 195978084 6760764 complement(998587..999717) 1 NC_011134.1 similar to ref|YP_596508.1| transposase [Streptococcus pyogenes MGAS9429]; transposase IS1548-like 999717 6760764 Sez_0957 Streptococcus equi subsp. zooepidemicus MGCS10565 transposase IS1548-like YP_002123328.1 998587 R 552526 CDS YP_002123329.1 195978085 6760762 complement(1000065..1000970) 1 NC_011134.1 similar to ref|YP_596728.1| diacylglycerol kinase family protein [Streptococcus pyogenes MGAS9429]; transcriptional regulator 1000970 6760762 Sez_0958 Streptococcus equi subsp. zooepidemicus MGCS10565 transcriptional regulator YP_002123329.1 1000065 R 552526 CDS YP_002123330.1 195978086 6760760 complement(1001080..1001730) 1 NC_011134.1 similar to ref|NP_269309.1| hemolysin III [Streptococcus pyogenes M1 GAS]; Unknown, possible extracellur hemolysin but lacks a SrtA secretion signal peptide.; hemolysin III HylIII 1001730 hylIII 6760760 hylIII Streptococcus equi subsp. zooepidemicus MGCS10565 hemolysin III HylIII YP_002123330.1 1001080 R 552526 CDS YP_002123331.1 195978087 6760757 complement(1001714..1002169) 1 NC_011134.1 similar to ref|NP_607242.1| hypothetical protein spyM18_1120 [Streptococcus pyogenes MGAS8232]; hypothetical protein 1002169 6760757 Sez_0960 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123331.1 1001714 R 552526 CDS YP_002123332.1 195978088 6760755 1002429..1003184 1 NC_011134.1 similar to ref|YP_329155.1| hypothetical protein SAK_0522 [Streptococcus agalactiae A909]; ubiquinone/menaquinone biosynthesis methyltransferase UbiE/COQ5 1003184 6760755 Sez_0961 Streptococcus equi subsp. zooepidemicus MGCS10565 ubiquinone/menaquinone biosynthesis methyltransferase UbiE/COQ5 YP_002123332.1 1002429 D 552526 CDS YP_002123333.1 195978089 6760753 1003212..1003550 1 NC_011134.1 similar to ref|NP_721671.1| hypothetical protein SMU.1300c [Streptococcus mutans UA159]; hypothetical protein 1003550 6760753 Sez_0962 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123333.1 1003212 D 552526 CDS YP_002123334.1 195978090 6760751 1003552..1003857 1 NC_011134.1 similar to ref|NP_607650.1| acetate kinase [Streptococcus pyogenes MGAS8232]; Catalysis of the reaction: ATP + acetate = ADP + acetyl phosphate.; acetate kinase 1003857 6760751 Sez_0963 Streptococcus equi subsp. zooepidemicus MGCS10565 acetate kinase YP_002123334.1 1003552 D 552526 CDS YP_002123335.1 195978091 6760749 1004615..1005352 1 NC_011134.1 similar to ref|NP_606739.1| response regulator [Streptococcus pyogenes MGAS8232]; Required for high-level post-exponential phase expression of a series of secreted proteins, has similarity with BlpR/FasA/SilA regulators.; accessory gene regulator protein A, response regulator FasA or ComE or BlpR 1005352 6760749 Sez_0964 Streptococcus equi subsp. zooepidemicus MGCS10565 accessory gene regulator protein A, response regulator FasA or ComE or BlpR YP_002123335.1 1004615 D 552526 CDS YP_002123336.1 195978092 6760747 1005725..1005925 1 NC_011134.1 similar to ref|YP_281761.1| bacteriocin [Streptococcus pyogenes MGAS5005]; bacteriocin 1005925 6760747 Sez_0965 Streptococcus equi subsp. zooepidemicus MGCS10565 bacteriocin YP_002123336.1 1005725 D 552526 CDS YP_002123337.1 195978093 6760745 1005992..1006846 1 NC_011134.1 similar to ref|NP_688943.1| ABC transporter, ATP-binding protein [Streptococcus agalactiae 2603V/R]; ABC transporter 1006846 6760745 Sez_0966 Streptococcus equi subsp. zooepidemicus MGCS10565 ABC transporter YP_002123337.1 1005992 D 552526 CDS YP_002123338.1 195978094 6760743 1006852..1007331 1 NC_011134.1 similar to ref|ZP_00789085.1| membrane protein [Streptococcus agalactiae 515]; Unknown, predicted to be Sec-indepently secreted by SecretomeP 2.0; hypothetical protein 1007331 6760743 Sez_0967 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123338.1 1006852 D 552526 CDS YP_002123339.1 195978095 6760741 1007358..1008014 1 NC_011134.1 similar to ref|YP_330508.1| hypothetical protein SAK_1913 [Streptococcus agalactiae A909]; hypothetical protein 1008014 6760741 Sez_0968 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123339.1 1007358 D 552526 CDS YP_002123340.1 195978096 6760739 1008276..1008506 1 NC_011134.1 similar to ref|YP_140101.1| pore-forming peptide, bacteriocin [Streptococcus thermophilus LMG 18311]; bacteriocin 1008506 6760739 Sez_0969 Streptococcus equi subsp. zooepidemicus MGCS10565 bacteriocin YP_002123340.1 1008276 D 552526 CDS YP_002123341.1 195978097 6760737 1009299..1010150 1 NC_011134.1 similar to ref|YP_140093.1| immunity/modification protein [Streptococcus thermophilus LMG 18311]; immunity modification protein 1010150 6760737 Sez_0970 Streptococcus equi subsp. zooepidemicus MGCS10565 immunity modification protein YP_002123341.1 1009299 D 552526 CDS YP_002123342.1 195978098 6760734 1010629..1010910 1 NC_011134.1 similar to ref|ZP_01835892.1| hypothetical protein CGSSp23BS72_00905 [Streptococcus pneumoniae SP23-BS72]; hypothetical protein 1010910 6760734 Sez_0971 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123342.1 1010629 D 552526 CDS YP_002123343.1 195978099 6760732 1011015..1013030 1 NC_011134.1 similar to ref|ZP_01835893.1| hypothetical protein CGSSp23BS72_00910 [Streptococcus pneumoniae SP23-BS72]; immunity protein, bacteriocin-associated integral membrane protein subfamily 1013030 6760732 Sez_0972 Streptococcus equi subsp. zooepidemicus MGCS10565 immunity protein, bacteriocin-associated integral membrane protein subfamily YP_002123343.1 1011015 D 552526 CDS YP_002123344.1 195978100 6760730 1013032..1013664 1 NC_011134.1 similar to ref|ZP_01821399.1| competence damage-inducible protein A [Streptococcus pneumoniae SP6-BS73]; ABC transporter 1013664 6760730 Sez_0973 Streptococcus equi subsp. zooepidemicus MGCS10565 ABC transporter YP_002123344.1 1013032 D 552526 CDS YP_002123345.1 195978101 6760728 1014676..1015530 1 NC_011134.1 essential GTPase; functions in ribosome assembly; binds a unique part of the 23S rRNA; interacts with ribosomal protein L25(Ctc); ribosomal biogenesis GTPase 1015530 rbgA 6760728 rbgA Streptococcus equi subsp. zooepidemicus MGCS10565 ribosomal biogenesis GTPase YP_002123345.1 1014676 D 552526 CDS YP_002123346.1 195978102 6760726 1015511..1016293 1 NC_011134.1 RNH2; RNase HII; binds manganese; endonuclease which specifically degrades the RNA of RNA-DNA hybrids; ribonuclease HII 1016293 rnhB 6760726 rnhB Streptococcus equi subsp. zooepidemicus MGCS10565 ribonuclease HII YP_002123346.1 1015511 D 552526 CDS YP_002123347.1 195978103 6760724 1016549..1017394 1 NC_011134.1 similar to ref|YP_598607.1| DNA processing protein [Streptococcus pyogenes MGAS10270]; nucleotide-binding protein Smf 1017394 smf 6760724 smf Streptococcus equi subsp. zooepidemicus MGCS10565 nucleotide-binding protein Smf YP_002123347.1 1016549 D 552526 CDS YP_002123348.1 195978104 6760721 1017486..1019627 1 NC_011134.1 catalyzes the ATP-dependent breakage of single-stranded DNA followed by passage and rejoining, maintains net negative superhelicity; DNA topoisomerase I 1019627 topA 6760721 topA Streptococcus equi subsp. zooepidemicus MGCS10565 DNA topoisomerase I YP_002123348.1 1017486 D 552526 CDS YP_002123349.1 195978105 6760719 1019715..1020389 1 NC_011134.1 similar to ref|YP_602534.1| hypothetical protein MGAS10750_Spy1040 [Streptococcus pyogenes MGAS10750]; secretion and acid tolerance protein SatD 1020389 satD 6760719 satD Streptococcus equi subsp. zooepidemicus MGCS10565 secretion and acid tolerance protein SatD YP_002123349.1 1019715 D 552526 CDS YP_002123350.1 195978106 6760716 1020410..1021123 1 NC_011134.1 similar to ref|ZP_00366032.1| COG4988: ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components [Streptococcus pyogenes M49 591]; secretion and acid tolerance protein SatE 1021123 satE 6760716 satE Streptococcus equi subsp. zooepidemicus MGCS10565 secretion and acid tolerance protein SatE YP_002123350.1 1020410 D 552526 CDS YP_002123351.1 195978107 6760713 1021540..1023261 1 NC_011134.1 similar to ref|ZP_01371554.1| transposase, IS4 [Desulfitobacterium hafniense DCB-2]; transposase IS4-like 1023261 6760713 Sez_0980 Streptococcus equi subsp. zooepidemicus MGCS10565 transposase IS4-like YP_002123351.1 1021540 D 552526 CDS YP_002123352.1 195978108 6760708 complement(1024453..1025502) 1 NC_011134.1 similar to ref|YP_598633.1| (Citrate (pro-3S)-lyase) ligase [Streptococcus pyogenes MGAS10270]; Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase.; [citrate (pro-3S)-lyase] ligase 1025502 citC 6760708 citC Streptococcus equi subsp. zooepidemicus MGCS10565 [citrate (pro-3S)-lyase] ligase YP_002123352.1 1024453 R 552526 CDS YP_002123353.1 195978109 6760706 1025677..1025826 1 NC_011134.1 similar to ref|YP_602540.1| Na+ transporting oxaloacetate decarboxylase beta chain [Streptococcus pyogenes MGAS10750]; bifunctional oxaloacetate decarboxylase subunit beta/methylmalonyl-CoA decarboxylase subunit beta 1025826 6760706 Sez_0984 Streptococcus equi subsp. zooepidemicus MGCS10565 bifunctional oxaloacetate decarboxylase subunit beta/methylmalonyl-CoA decarboxylase subunit beta YP_002123353.1 1025677 D 552526 CDS YP_002123354.1 195978110 6760704 1025961..1027157 1 NC_011134.1 similar to ref|NP_603429.1| Hypothetical membrane-spanning protein [Fusobacterium nucleatum subsp. nucleatum ATCC 25586]; ammonia monooxygenase 1027157 6760704 Sez_0985 Streptococcus equi subsp. zooepidemicus MGCS10565 ammonia monooxygenase YP_002123354.1 1025961 D 552526 CDS YP_002123355.1 195978111 6760702 complement(1027243..1028127) 1 NC_011134.1 similar to ref|NP_664630.1| CitG protein,2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase [Streptococcus pyogenes MGAS315]; Catalyzes the formation of 2-(5''-triphosphoribosyl)-3'- dephosphocoenzyme-A, the precursor of the prosthetic group of the holo-acyl carrier protein (gamma chain) of citrate lyase, from ATP and dephospho-CoA.; 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase 1028127 citG 6760702 citG Streptococcus equi subsp. zooepidemicus MGCS10565 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase YP_002123355.1 1027243 R 552526 CDS YP_002123356.1 195978112 6760699 complement(1028120..1028815) 1 NC_011134.1 similar to ref|YP_602542.1| Transcriptional regulator, GntR family [Streptococcus pyogenes MGAS10750]; GntR family transcriptional regulator 1028815 6760699 Sez_0987 Streptococcus equi subsp. zooepidemicus MGCS10565 GntR family transcriptional regulator YP_002123356.1 1028120 R 552526 CDS YP_002123357.1 195978113 6760697 complement(1028968..1030371) 1 NC_011134.1 similar to ref|YP_060207.1| Mg2+/citrate complex secondary transporter [Streptococcus pyogenes MGAS10394]; Transports the free citrate anion. Probably cotransports citrate and at least three or four protons. The citrate uptake is inhibited by the presence of magnesium ions.; Mg2+/citrate complex transporter 1030371 citN 6760697 citN Streptococcus equi subsp. zooepidemicus MGCS10565 Mg2+/citrate complex transporter YP_002123357.1 1028968 R 552526 CDS YP_002123358.1 195978114 6760694 1030410..1030616 1 NC_011134.1 hypothetical protein 1030616 6760694 Sez_0989 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123358.1 1030410 D 552526 CDS YP_002123359.1 195978115 6760692 1030753..1031097 1 NC_011134.1 similar to ref|NP_607255.1| hypothetical protein spyM18_1133 [Streptococcus pyogenes MGAS8232]; hypothetical protein 1031097 6760692 Sez_0990 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123359.1 1030753 D 552526 CDS YP_002123360.1 195978116 6760689 1031115..1031501 1 NC_011134.1 composes the biotin carboxyl carrier protein subunit of the acetyl-CoA carboxylase complex, the enzyme that catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, which in turn controls the rate of fatty acid metabolism; acetyl-CoA carboxylase biotin carboxyl carrier protein subunit 1031501 bcc 6760689 bcc Streptococcus equi subsp. zooepidemicus MGCS10565 acetyl-CoA carboxylase biotin carboxyl carrier protein subunit YP_002123360.1 1031115 D 552526 CDS YP_002123361.1 195978117 6760687 1031552..1032673 1 NC_011134.1 similar to ref|YP_280344.1| oxaloacetate decarboxylase beta chain [Streptococcus pyogenes MGAS6180]; Lyase and sodium transporter.; oxaloacetate decarboxylase subunit beta OadB 1032673 oadB 6760687 oadB Streptococcus equi subsp. zooepidemicus MGCS10565 oxaloacetate decarboxylase subunit beta OadB YP_002123361.1 1031552 D 552526 CDS YP_002123362.1 195978118 6760684 1032688..1032822 1 NC_011134.1 similar to ref|YP_060211.1| hypothetical protein M6_Spy0893 [Streptococcus pyogenes MGAS10394]; hypothetical protein 1032822 6760684 Sez_0993 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123362.1 1032688 D 552526 CDS YP_002123363.1 195978119 6760682 1032855..1033163 1 NC_011134.1 acyl carrier protein; with CitE and CitF catalyzes the formation of oxaloacetate from citrate; citrate lyase subunit gamma 1033163 citD 6760682 citD Streptococcus equi subsp. zooepidemicus MGCS10565 citrate lyase subunit gamma YP_002123363.1 1032855 D 552526 CDS YP_002123364.1 195978120 6760677 1033175..1034038 1 NC_011134.1 similar to ref|YP_598629.1| Citrate lyase beta chain / Citryl-CoA lyase subunit [Streptococcus pyogenes MGAS10270]; citrate lyase subunit beta CitE 1034038 citE 6760677 citE Streptococcus equi subsp. zooepidemicus MGCS10565 citrate lyase subunit beta CitE YP_002123364.1 1033175 D 552526 CDS YP_002123365.1 195978121 6760675 1034040..1035572 1 NC_011134.1 similar to ref|YP_001128449.1| citrate lyase alpha subunit [Streptococcus pyogenes str. Manfredo]; citrate lyase subunit alpha CitF 1035572 citF 6760675 citF Streptococcus equi subsp. zooepidemicus MGCS10565 citrate lyase subunit alpha CitF YP_002123365.1 1034040 D 552526 CDS YP_002123366.1 195978122 6760673 1035565..1036125 1 NC_011134.1 2'-(5''-phosphoribosyl)-3'-dephospho-CoA transferase; holo-citrate lyase synthase; CitG forms the prosthetic group precursor 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA which is then transferred to apo-ACP by CitX to produce holo-ACP and pyrophosphate; 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase 1036125 citX 6760673 citX Streptococcus equi subsp. zooepidemicus MGCS10565 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase YP_002123366.1 1035565 D 552526 CDS YP_002123367.1 195978123 6760669 complement(1037812..1038171) 1 NC_011134.1 similar to ref|NP_607265.1| hypothetical protein spyM18_1144 [Streptococcus pyogenes MGAS8232]; hypothetical protein 1038171 6760669 Sez_1000 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123367.1 1037812 R 552526 CDS YP_002123368.1 195978124 6760667 1038172..1038309 1 NC_011134.1 hypothetical protein 1038309 6760667 Sez_1001 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123368.1 1038172 D 552526 CDS YP_002123369.1 195978125 6760665 1038621..1039373 1 NC_011134.1 similar to dbj|BAB83943.1| mutans bacitracin-resistance related protein A [Streptococcus mutans]; Part of the ABC transporter complex which could be involved in peptide resistance. Responsible for energy coupling to the transport system ().; ABC transporter ATP-binding protein 1039373 6760665 Sez_1002 Streptococcus equi subsp. zooepidemicus MGCS10565 ABC transporter ATP-binding protein YP_002123369.1 1038621 D 552526 CDS YP_002123370.1 195978126 6760662 1039376..1041331 1 NC_011134.1 similar to ref|NP_687986.1| ABC transporter, permease, [Streptococcus agalactiae 2603V/R]; Part of the ABC transporter complex bceAB (TC 3.A.1.123.5) involved in bacitracin export.; bacitracin export permease BceB 1041331 bceB 6760662 bceB Streptococcus equi subsp. zooepidemicus MGCS10565 bacitracin export permease BceB YP_002123370.1 1039376 D 552526 CDS YP_002123371.1 195978127 6760660 1041375..1042040 1 NC_011134.1 similar to ref|NP_687987.1| DNA-binding response regulator [Streptococcus agalactiae 2603V/R]; Member of the two-component regulatory system bceS/bceR involved in the regulation of bacitracin resistance. When activated by bceS, binds to the upstream region of the bceAB promoter and up-regulates the expression of these two genes.; TCS response regulator BceR 1042040 bceR 6760660 bceR Streptococcus equi subsp. zooepidemicus MGCS10565 TCS response regulator BceR YP_002123371.1 1041375 D 552526 CDS YP_002123372.1 195978128 6760658 1042037..1043014 1 NC_011134.1 similar to ref|NP_721404.1| histidine kinase [Streptococcus mutans UA159]; Signal transduction histidine kinase; TCS senso kinase BceS 1043014 bceS 6760658 bceS Streptococcus equi subsp. zooepidemicus MGCS10565 TCS senso kinase BceS YP_002123372.1 1042037 D 552526 CDS YP_002123373.1 195978129 6760655 complement(1043152..1044222) 1 NC_011134.1 site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; cell division protein FtsK may regulate the XerS; site-specific tyrosine recombinase XerS 1044222 xerS 6760655 xerS Streptococcus equi subsp. zooepidemicus MGCS10565 site-specific tyrosine recombinase XerS YP_002123373.1 1043152 R 552526 CDS YP_002123374.1 195978130 6760653 complement(1044374..1044811) 1 NC_011134.1 similar to ref|NP_687863.1| GtrA family protein [Streptococcus agalactiae 2603V/R]; Unknown. GtrA is predicted to be an integral membrane protein with 4 transmembrane spans. It is involved is in O antigen modification by Shigella flexneri bacteriophage X (SfX), but does not determine the specificity of glucosylation. Its function remains unknown, but it may play a role in translocation of UDP phosphate linked glucose (UndP-Glc) across the cytoplasmic membrane.; GtrA family protein 1044811 6760653 Sez_1007 Streptococcus equi subsp. zooepidemicus MGCS10565 GtrA family protein YP_002123374.1 1044374 R 552526 CDS YP_002123375.1 195978131 6760651 1045006..1045704 1 NC_011134.1 similar to ref|YP_598637.1| phage transcriptional repressor [Streptococcus pyogenes MGAS10270]; Phage transcriptional repressor 1045704 6760651 Sez_1008 Streptococcus equi subsp. zooepidemicus MGCS10565 Phage transcriptional repressor YP_002123375.1 1045006 D 552526 CDS YP_002123376.1 195978132 6760649 complement(1046056..1046850) 1 NC_011134.1 similar to ref|ZP_02075633.1| hypothetical protein CLOL250_02409 [Clostridium sp. L2-50]; hypothetical protein 1046850 6760649 Sez_1009 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123376.1 1046056 R 552526 CDS YP_002123377.1 195978133 6760647 complement(1047063..1048610) 1 NC_011134.1 contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway; GMP synthase 1048610 guaA 6760647 guaA Streptococcus equi subsp. zooepidemicus MGCS10565 GMP synthase YP_002123377.1 1047063 R 552526 CDS YP_002123378.1 195978134 6760645 complement(1048756..1048926) 1 NC_011134.1 hypothetical protein 1048926 6760645 Sez_1011 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123378.1 1048756 R 552526 CDS YP_002123379.1 195978135 6760643 1048900..1049598 1 NC_011134.1 similar to ref|ZP_00366165.1| COG2188: Transcriptional regulators [Streptococcus pyogenes M49 591]; GntR family transcriptional regulator 1049598 6760643 Sez_1012 Streptococcus equi subsp. zooepidemicus MGCS10565 GntR family transcriptional regulator YP_002123379.1 1048900 D 552526 CDS YP_002123380.1 195978136 6760641 1049801..1050142 1 NC_011134.1 similar to ref|NP_269340.1| hypothetical protein SPy_1201 [Streptococcus pyogenes M1 GAS]; Not known. Could take part in the signal recognition particle (SRP) pathway. This is inferred due to the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein.; DNA-binding protein 1050142 6760641 Sez_1013 Streptococcus equi subsp. zooepidemicus MGCS10565 DNA-binding protein YP_002123380.1 1049801 D 552526 CDS YP_002123381.1 195978137 6760639 1050157..1051728 1 NC_011134.1 similar to ref|YP_282278.1| signal recognition particle, subunit FFH/SRP54 [Streptococcus pyogenes MGAS5005]; Necessary for efficient export of extra-cytoplasmic proteins. Binds to the signal sequence when it emerges from the ribosomes.; signal recognition particle protein Ffh 1051728 ffh 6760639 ffh Streptococcus equi subsp. zooepidemicus MGCS10565 signal recognition particle protein Ffh YP_002123381.1 1050157 D 552526 CDS YP_002123382.1 195978138 6760637 complement(1051881..1053107) 1 NC_011134.1 similar to ref|YP_060227.1| UDP-N-acetylmuramoylpentapeptide-lysine N(6)-alanyltransferase [Streptococcus pyogenes MGAS10394]; UDP-N-acetylmuramoylpentapeptide-lysine N(6)-alanyltransferase MurM 1053107 murM 6760637 murM Streptococcus equi subsp. zooepidemicus MGCS10565 UDP-N-acetylmuramoylpentapeptide-lysine N(6)-alanyltransferase MurM YP_002123382.1 1051881 R 552526 CDS YP_002123383.1 195978139 6760635 complement(1053329..1054300) 1 NC_011134.1 similar to ref|ZP_00780941.1| extracellular protein [Streptococcus agalactiae 18RS21]; hypothetical protein 1054300 6760635 Sez_1016 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123383.1 1053329 R 552526 CDS YP_002123384.1 195978140 6760899 complement(1054613..1055053) 1 NC_011134.1 similar to ref|ZP_01823706.1| histidine triad protein [Streptococcus pneumoniae SP9-BS68]; histidine triad protein HtpA 1055053 htpA 6760899 htpA Streptococcus equi subsp. zooepidemicus MGCS10565 histidine triad protein HtpA YP_002123384.1 1054613 R 552526 CDS YP_002123385.1 195978141 6760435 complement(1055050..1055991) 1 NC_011134.1 similar to emb|CAC85395.1| laminin binding protein [Streptococcus dysgalactiae subsp. equisimilis]; laminin-binding surface protein Lmb 1055991 lmb 6760435 lmb Streptococcus equi subsp. zooepidemicus MGCS10565 laminin-binding surface protein Lmb YP_002123385.1 1055050 R 552526 CDS YP_002123386.1 195978142 6760433 complement(1056421..1056888) 1 NC_011134.1 similar to ref|NP_687974.1| glyoxylase family protein [Streptococcus agalactiae 2603V/R]; Catalysis of the reaction: (R)-S-lactoylglutathione = glutathione + methylglyoxal.; lactoylglutathione lyase 1056888 6760433 Sez_1019 Streptococcus equi subsp. zooepidemicus MGCS10565 lactoylglutathione lyase YP_002123386.1 1056421 R 552526 CDS YP_002123387.1 195978143 6760431 complement(1056932..1057645) 1 NC_011134.1 similar to ref|YP_598598.1| Sortase [Streptococcus pyogenes MGAS10270]; Transpeptidation reaction linking surface proteins to peptidoglycan.; A family sortase SrtA 1057645 srtA 6760431 srtA Streptococcus equi subsp. zooepidemicus MGCS10565 A family sortase SrtA YP_002123387.1 1056932 R 552526 CDS YP_002123388.1 195978144 6760427 complement(1057692..1060187) 1 NC_011134.1 negatively supercoils closed circular double-stranded DNA; DNA gyrase subunit A 1060187 gyrA 6760427 gyrA Streptococcus equi subsp. zooepidemicus MGCS10565 DNA gyrase subunit A YP_002123388.1 1057692 R 552526 CDS YP_002123389.1 195978145 6760425 1060379..1061362 1 NC_011134.1 Converts (S)-lactate and NAD(+) to pyruvate and NADH; L-lactate dehydrogenase 1061362 ldh 6760425 ldh Streptococcus equi subsp. zooepidemicus MGCS10565 L-lactate dehydrogenase YP_002123389.1 1060379 D 552526 CDS YP_002123390.1 195978146 6760423 complement(1061583..1062893) 1 NC_011134.1 similar to gb|AAL78063.1| NADH oxidase [Streptococcus equi subsp. zooepidemicus]; Catalyzes the four-electron reduction of molecular oxygen to water.; NADH oxidase H2O-forming Nox 1062893 nox 6760423 nox Streptococcus equi subsp. zooepidemicus MGCS10565 NADH oxidase H2O-forming Nox YP_002123390.1 1061583 R 552526 CDS YP_002123391.1 195978147 6760421 complement(1063200..1063802) 1 NC_011134.1 similar to ref|YP_598592.1| antigen-like protein [Streptococcus pyogenes MGAS10270]; COG0741: Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains).; pneumococcal vaccine antigen A-like protein PvaA 1063802 pvaA 6760421 pvaA Streptococcus equi subsp. zooepidemicus MGCS10565 pneumococcal vaccine antigen A-like protein PvaA YP_002123391.1 1063200 R 552526 CDS YP_002123392.1 195978148 6760419 complement(1063803..1064780) 1 NC_011134.1 similar to ref|YP_598591.1| hypothetical protein MGAS10270_Spy0982 [Streptococcus pyogenes MGAS10270]; hypothetical protein 1064780 6760419 Sez_1025 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123392.1 1063803 R 552526 CDS YP_002123393.1 195978149 6760412 complement(1064783..1066042) 1 NC_011134.1 catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate; serine hydroxymethyltransferase 1066042 glyA 6760412 glyA Streptococcus equi subsp. zooepidemicus MGCS10565 serine hydroxymethyltransferase YP_002123393.1 1064783 R 552526 CDS YP_002123394.1 195978150 6760409 complement(1066054..1066485) 1 NC_011134.1 similar to ref|ZP_00366378.1| COG0454: Histone acetyltransferase HPA2 and related acetyltransferases [Streptococcus pyogenes M49 591]; phosphinothricin N-acetyltransferase PhnO 1066485 phnO 6760409 phnO Streptococcus equi subsp. zooepidemicus MGCS10565 phosphinothricin N-acetyltransferase PhnO YP_002123394.1 1066054 R 552526 CDS YP_002123395.1 195978151 6760407 complement(1066499..1067092) 1 NC_011134.1 similar to ref|ZP_00366379.1| COG0009: translation factor (SUA5) [Streptococcus pyogenes M49 591]; Sua5/YciO/YrdC/YwlC family protein 1067092 6760407 Sez_1028 Streptococcus equi subsp. zooepidemicus MGCS10565 Sua5/YciO/YrdC/YwlC family protein YP_002123395.1 1066499 R 552526 CDS YP_002123396.1 195978152 6760405 complement(1067064..1067912) 1 NC_011134.1 similar to ref|YP_001128483.1| methyltransferase [Streptococcus pyogenes str. Manfredo]; Methylates The Translation Termination Release Factor Rf1 On Gln-235 And Rf2 On Gln-252.; polypeptide chain release factor methylase 1067912 6760405 Sez_1029 Streptococcus equi subsp. zooepidemicus MGCS10565 polypeptide chain release factor methylase YP_002123396.1 1067064 R 552526 CDS YP_002123397.1 195978153 6760403 complement(1067909..1068991) 1 NC_011134.1 recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2; peptide chain release factor 1 1068991 prfA 6760403 prfA Streptococcus equi subsp. zooepidemicus MGCS10565 peptide chain release factor 1 YP_002123397.1 1067909 R 552526 CDS YP_002123398.1 195978154 6760401 complement(1069033..1069602) 1 NC_011134.1 similar to ref|NP_269291.1| thymidine kinase [Streptococcus pyogenes M1 GAS]; Phosphorylates Both Thymidine And Deoxyuridine.; thymidine kinase Tdk 1069602 tdk 6760401 tdk Streptococcus equi subsp. zooepidemicus MGCS10565 thymidine kinase Tdk YP_002123398.1 1069033 R 552526 CDS YP_002123399.1 195978155 6760399 1069594..1069806 1 NC_011134.1 hypothetical protein 1069806 6760399 Sez_1032 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123399.1 1069594 D 552526 CDS YP_002123400.1 195978156 6760397 1069787..1069972 1 NC_011134.1 4-OT; member of subfamily 5; forms a dimer; the function in the Escherichia coli cell is unknown; 4-oxalocrotonate tautomerase 1069972 6760397 Sez_1033 Streptococcus equi subsp. zooepidemicus MGCS10565 4-oxalocrotonate tautomerase YP_002123400.1 1069787 D 552526 CDS YP_002123401.1 195978157 6760395 1070027..1070968 1 NC_011134.1 similar to ref|YP_598583.1| Iron-sulfur cluster assembly/repair protein ApbE [Streptococcus pyogenes MGAS10270]; Involved in the conversion of aminoimidazole ribotide (AIR), a purine intermediate, to the 4-amino-5-hydroxymethyl-2- methyl pyrimidine (HMP) moiety of thiamine.; thiamin biosynthesis lipoprotein ApbE 1070968 apbE 6760395 apbE Streptococcus equi subsp. zooepidemicus MGCS10565 thiamin biosynthesis lipoprotein ApbE YP_002123401.1 1070027 D 552526 CDS YP_002123402.1 195978158 6760392 complement(1071243..1071827) 1 NC_011134.1 Catalyzes the transfer of the phosphoribosyl moiety from 5-phospho--D-ribosyl-1-pyrophosphate (PRib-PP) to the 6-oxo-guanine and -xanthine; xanthine phosphoribosyltransferase 1071827 xpt 6760392 xpt Streptococcus equi subsp. zooepidemicus MGCS10565 xanthine phosphoribosyltransferase YP_002123402.1 1071243 R 552526 CDS YP_002123403.1 195978159 6760970 complement(1072010..1072996) 1 NC_011134.1 similar to ref|ZP_00365512.1| COG0516: IMP dehydrogenase/GMP reductase [Streptococcus pyogenes M49 591]; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.; guanosine 5'-monophosphate oxidoreductase 1072996 guaC 6760970 guaC Streptococcus equi subsp. zooepidemicus MGCS10565 guanosine 5'-monophosphate oxidoreductase YP_002123403.1 1072010 R 552526 CDS YP_002123404.1 195978160 6760389 complement(1073352..1074869) 1 NC_011134.1 similar to ref|YP_598579.1| Glycine betaine transport system permease / Glycine betaine-binding protein [Streptococcus pyogenes MGAS10270]; Involved in a high affinity multicomponent binding- protein-dependent transport system for glycine betaine, carnitine and choline; probably responsible for the translocation of the substrate across the membrane.; glycine betaine/carnitine/choline transport system permease OpuCB 1074869 opuCB 6760389 opuCB Streptococcus equi subsp. zooepidemicus MGCS10565 glycine betaine/carnitine/choline transport system permease OpuCB YP_002123404.1 1073352 R 552526 CDS YP_002123405.1 195978161 6760387 complement(1074877..1075605) 1 NC_011134.1 similar to ref|NP_664595.1| ABC transporter (ATP-binding protein) [Streptococcus pyogenes MGAS315]; Involved in a high affinity multicomponent binding- protein-dependent transport system for glycine betaine, carnitine and choline; probably responsible for energy coupling to the transport system.; glycine betaine/carnitine/choline transport ATP-binding protein OpuCA 1075605 opuCA 6760387 opuCA Streptococcus equi subsp. zooepidemicus MGCS10565 glycine betaine/carnitine/choline transport ATP-binding protein OpuCA YP_002123405.1 1074877 R 552526 CDS YP_002123406.1 195978162 6760385 1075860..1076546 1 NC_011134.1 similar to ref|YP_602497.1| Na+ driven multidrug efflux pump [Streptococcus pyogenes MGAS10750]; Na+ driven multidrug efflux pump 1076546 6760385 Sez_1039 Streptococcus equi subsp. zooepidemicus MGCS10565 Na+ driven multidrug efflux pump YP_002123406.1 1075860 D 552526 CDS YP_002123407.1 195978163 6760383 complement(1076651..1077421) 1 NC_011134.1 similar to ref|YP_280295.1| short chain dehydrogenase [Streptococcus pyogenes MGAS6180]; Catalyzes the NADP-dependent oxidation of L-allo- threonine and L-serine.; NADP-dependent L-serine/L-allo-threonine dehydrogenase 1077421 6760383 Sez_1040 Streptococcus equi subsp. zooepidemicus MGCS10565 NADP-dependent L-serine/L-allo-threonine dehydrogenase YP_002123407.1 1076651 R 552526 CDS YP_002123408.1 195978164 6760381 complement(1078522..1079418) 1 NC_011134.1 similar to ref|NP_664590.1| ribosomal large subunit pseudouridine synthase [Streptococcus pyogenes MGAS315]; Responsible For Synthesis Of Pseudouridine From Uracil At Positions 1911, 1915 And 1917 In 23s Ribosomal RNA; similar to Bacillus subtilis YjbO type; ribosomal large subunit pseudouridine synthase D 1079418 yjbO 6760381 yjbO Streptococcus equi subsp. zooepidemicus MGCS10565 ribosomal large subunit pseudouridine synthase D YP_002123408.1 1078522 R 552526 CDS YP_002123409.1 195978165 6760378 complement(1079415..1080242) 1 NC_011134.1 catalyzes the phosphorylation of NAD to NADP; inorganic polyphosphate/ATP-NAD kinase 1080242 ppnK 6760378 ppnK Streptococcus equi subsp. zooepidemicus MGCS10565 inorganic polyphosphate/ATP-NAD kinase YP_002123409.1 1079415 R 552526 CDS YP_002123410.1 195978166 6760375 complement(1080226..1080897) 1 NC_011134.1 similar to ref|NP_269279.1| GTP pyrophosphokinase [Streptococcus pyogenes M1 GAS]; In eubacteria ppGpp (guanosine 3'-diphosphate 5-'diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. This enzyme catalyzes the formation of pppGpp which is then hydrolyzed to form ppGpp.; GTP pyrophosphokinase 1080897 relA 6760375 relA Streptococcus equi subsp. zooepidemicus MGCS10565 GTP pyrophosphokinase YP_002123410.1 1080226 R 552526 CDS YP_002123411.1 195978167 6761071 1080992..1081564 1 NC_011134.1 similar to ref|YP_282209.1| adenylate cyclase family [Streptococcus pyogenes MGAS5005]; adenylate cyclase 1081564 6761071 Sez_1046 Streptococcus equi subsp. zooepidemicus MGCS10565 adenylate cyclase YP_002123411.1 1080992 D 552526 CDS YP_002123412.1 195978168 6761182 1081699..1082673 1 NC_011134.1 catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP; ribose-phosphate pyrophosphokinase 1082673 prs 6761182 prs Streptococcus equi subsp. zooepidemicus MGCS10565 ribose-phosphate pyrophosphokinase YP_002123412.1 1081699 D 552526 CDS YP_002123413.1 195978169 6760372 1082676..1083803 1 NC_011134.1 similar to ref|YP_001128501.1| cysteine desulfurase [Streptococcus pyogenes str. Manfredo]; Catalyzes the removal of elemental sulfur from cysteine to produce alanine.; cysteine desulfurase IscS 1083803 iscS 6760372 iscS Streptococcus equi subsp. zooepidemicus MGCS10565 cysteine desulfurase IscS YP_002123413.1 1082676 D 552526 CDS YP_002123414.1 195978170 6760370 1083793..1084140 1 NC_011134.1 similar to ref|NP_269275.1| hypothetical protein SPy_1121 [Streptococcus pyogenes M1 GAS]; hypothetical protein 1084140 6760370 Sez_1049 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123414.1 1083793 D 552526 CDS YP_002123415.1 195978171 6761031 1084386..1085075 1 NC_011134.1 modulates transcription in response to the NADH/NAD(+) redox state; redox-sensing transcriptional repressor Rex 1085075 rex 6761031 rex Streptococcus equi subsp. zooepidemicus MGCS10565 redox-sensing transcriptional repressor Rex YP_002123415.1 1084386 D 552526 CDS YP_002123416.1 195978172 6760368 1085075..1085782 1 NC_011134.1 similar to ref|NP_607204.1| hypothetical protein spyM18_1080 [Streptococcus pyogenes MGAS8232]; glutamine amidotransferase 1085782 6760368 Sez_1051 Streptococcus equi subsp. zooepidemicus MGCS10565 glutamine amidotransferase YP_002123416.1 1085075 D 552526 CDS YP_002123417.1 195978173 6761201 complement(1085784..1086461) 1 NC_011134.1 Involved in DNA double-strand break repair and recombination. Promotes the annealing of complementary single-stranded DNA and by simulation of RAD51 recombinase; DNA repair protein RadC 1086461 radC 6761201 radC Streptococcus equi subsp. zooepidemicus MGCS10565 DNA repair protein RadC YP_002123417.1 1085784 R 552526 CDS YP_002123418.1 195978174 6761145 complement(1086627..1087754) 1 NC_011134.1 similar to ref|YP_282202.1| hypothetical membrane spanning protein [Streptococcus pyogenes MGAS5005]; permease 1087754 6761145 Sez_1053 Streptococcus equi subsp. zooepidemicus MGCS10565 permease YP_002123418.1 1086627 R 552526 CDS YP_002123419.1 195978175 6761093 complement(1088119..1088787) 1 NC_011134.1 similar to ref|YP_060154.1| Lipase/Acylhydrolase family protein [Streptococcus pyogenes MGAS10394]; lipase/acylhydrolase family protein 1088787 6761093 Sez_1054 Streptococcus equi subsp. zooepidemicus MGCS10565 lipase/acylhydrolase family protein YP_002123419.1 1088119 R 552526 CDS YP_002123420.1 195978176 6761263 complement(1088938..1090500) 1 NC_011134.1 similar to ref|YP_596686.1| chloride channel protein [Streptococcus pyogenes MGAS9429]; Probably acts as an electrical shunt for an outwardly-directed proton pump that is linked to amino acid decarboxylation, as part of the extreme acid resistance (XAR) response.; voltage-gated chloride channel family protein 1090500 6761263 Sez_1055 Streptococcus equi subsp. zooepidemicus MGCS10565 voltage-gated chloride channel family protein YP_002123420.1 1088938 R 552526 CDS YP_002123421.1 195978177 6761212 complement(1090629..1091702) 1 NC_011134.1 similar to ref|YP_001128516.1| spermidine/putrescine extracellular binding protein [Streptococcus pyogenes str. Manfredo]; Required for the activity of the bacterial periplasmic transport system of putrescine and spermidine. Polyamine binding protein.; spermidine putrescineABC transporter substrate-binding protein PotD 1091702 potD 6761212 potD Streptococcus equi subsp. zooepidemicus MGCS10565 spermidine putrescineABC transporter substrate-binding protein PotD YP_002123421.1 1090629 R 552526 CDS YP_002123422.1 195978178 6761105 complement(1091695..1092471) 1 NC_011134.1 similar to ref|NP_607191.1| spermidine/putrescine ABC transporter (permease) [Streptococcus pyogenes MGAS8232]; Required for the activity of the bacterial periplasmic transport system of putrescine and spermidine.; spermidine/putrescine transport system permease PotC 1092471 potC 6761105 potC Streptococcus equi subsp. zooepidemicus MGCS10565 spermidine/putrescine transport system permease PotC YP_002123422.1 1091695 R 552526 CDS YP_002123423.1 195978179 6761255 complement(1092468..1093262) 1 NC_011134.1 similar to ref|YP_280272.1| spermidine/putrescine transport system permease [Streptococcus pyogenes MGAS6180]; Required for the activity of the bacterial periplasmic transport system of putrescine and spermidine.; spermidine/putrescine transport system permease PotB 1093262 potB 6761255 potB Streptococcus equi subsp. zooepidemicus MGCS10565 spermidine/putrescine transport system permease PotB YP_002123423.1 1092468 R 552526 CDS YP_002123424.1 195978180 6761129 complement(1093246..1094400) 1 NC_011134.1 similar to ref|YP_060142.1| PotA [Streptococcus pyogenes MGAS10394]; Part of the ABC transporter complex potABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.; spermidine/putrescine import ATP-binding protein PotA 1094400 potA 6761129 potA Streptococcus equi subsp. zooepidemicus MGCS10565 spermidine/putrescine import ATP-binding protein PotA YP_002123424.1 1093246 R 552526 CDS YP_002123425.1 195978181 6760989 complement(1094446..1095339) 1 NC_011134.1 catalyzes the reduction of UDP-N-acetylglucosamine enolpyruvate to form UDP-N-acetylmuramate in peptidoglycan biosynthesis; UDP-N-acetylenolpyruvoylglucosamine reductase 1095339 murB 6760989 murB Streptococcus equi subsp. zooepidemicus MGCS10565 UDP-N-acetylenolpyruvoylglucosamine reductase YP_002123425.1 1094446 R 552526 CDS YP_002123426.1 195978182 6761053 complement(1095428..1095934) 1 NC_011134.1 similar to ref|YP_598549.1| 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase [Streptococcus pyogenes MGAS10270]; Dihydrofolate biosynthesis; first step, Catalysis of the reaction: ATP + 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine = AMP + 2-amino-7, 8-dihydro-4-hydroxy-6-(diphosphooxymethyl)pteridine.; 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase 1095934 folK 6761053 folK Streptococcus equi subsp. zooepidemicus MGCS10565 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase YP_002123426.1 1095428 R 552526 CDS YP_002123427.1 195978183 6761055 complement(1095931..1096293) 1 NC_011134.1 similar to emb|CAD31136.1| dihydroneopterin aldolase [Streptococcus pyogenes]; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin.; dihydroneopterin aldolase FolB 1096293 folB 6761055 folB Streptococcus equi subsp. zooepidemicus MGCS10565 dihydroneopterin aldolase FolB YP_002123427.1 1095931 R 552526 CDS YP_002123428.1 195978184 6761140 complement(1096297..1097097) 1 NC_011134.1 similar to emb|CAA04242.1| dihydropteroate synthase [Streptococcus pyogenes]; DHPS catalyzes the formation of the immediate precursor of folic acid. It is implicated in resistance to sulfonamide.; dihydropteroate synthase FolP 1097097 folP 6761140 folP Streptococcus equi subsp. zooepidemicus MGCS10565 dihydropteroate synthase FolP YP_002123428.1 1096297 R 552526 CDS YP_002123429.1 195978185 6761220 complement(1097105..1097671) 1 NC_011134.1 similar to emb|CAC39312.1| GTP Cyclohydrolase [Streptococcus pyogenes]; Tetrahydrofolate biosynthesis; first step.; GTP cyclohydrolase I 1097671 folE 6761220 folE Streptococcus equi subsp. zooepidemicus MGCS10565 GTP cyclohydrolase I YP_002123429.1 1097105 R 552526 CDS YP_002123430.1 195978186 6761025 complement(1097729..1098760) 1 NC_011134.1 similar to ref|YP_598545.1| Folylpolyglutamate synthase / Dihydrofolate synthase [Streptococcus pyogenes MGAS10270]; Conversion of folates to polyglutamate derivatives.; dihydrofolate synthase / folylpolyglutamate synthase FolC 1098760 folC 6761025 folC Streptococcus equi subsp. zooepidemicus MGCS10565 dihydrofolate synthase / folylpolyglutamate synthase FolC YP_002123430.1 1097729 R 552526 CDS YP_002123431.1 195978187 6761290 complement(1099152..1099958) 1 NC_011134.1 similar to ref|YP_819981.1| homoserine kinase [Streptococcus thermophilus LMD-9]; Threonine biosynthesis from asparate; fourth step.; homoserine kinase ThrB 1099958 thrB 6761290 thrB Streptococcus equi subsp. zooepidemicus MGCS10565 homoserine kinase ThrB YP_002123431.1 1099152 R 552526 CDS YP_002123432.1 195978188 6760365 complement(1100014..1101297) 1 NC_011134.1 catalyzes the formation of L-aspartate 4-semialdehyde from L-homoserine; homoserine dehydrogenase 1101297 hom 6760365 hom Streptococcus equi subsp. zooepidemicus MGCS10565 homoserine dehydrogenase YP_002123432.1 1100014 R 552526 CDS YP_002123433.1 195978189 6760362 1101514..1102434 1 NC_011134.1 similar to ref|NP_664560.1| hypothetical protein SpyM3_0756 [Streptococcus pyogenes MGAS315]; Required for the synthesis of linear beta-1,6-linked glucosaminoglycans.; polysaccharide deacetylase 1102434 6760362 Sez_1068 Streptococcus equi subsp. zooepidemicus MGCS10565 polysaccharide deacetylase YP_002123433.1 1101514 D 552526 CDS YP_002123434.1 195978190 6760359 complement(1102724..1103530) 1 NC_011134.1 similar to ref|YP_061057.1| Streptodornase [Streptococcus pyogenes MGAS10394]; Contributes to resistance to the host immune response in part by degrading neutrophil extracellular traps (NETs).; streptodornase type B SdzB 1103530 sdzB 6760359 sdzB Streptococcus equi subsp. zooepidemicus MGCS10565 streptodornase type B SdzB YP_002123434.1 1102724 R 552526 CDS YP_002123435.1 195978191 6760356 complement(1104031..1104450) 1 NC_011134.1 catalyzes the formation of nucleoside triphosphate from ATP and nucleoside diphosphate; nucleoside diphosphate kinase 1104450 ndk 6760356 ndk Streptococcus equi subsp. zooepidemicus MGCS10565 nucleoside diphosphate kinase YP_002123435.1 1104031 R 552526 CDS YP_002123436.1 195978192 6760354 1104453..1104590 1 NC_011134.1 hypothetical protein 1104590 6760354 Sez_1071 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123436.1 1104453 D 552526 CDS YP_002123437.1 195978193 6760715 1104821..1106914 1 NC_011134.1 similar to ref|YP_598361.1| ATP-dependent endopeptidase clp ATP-binding subunit clpL [Streptococcus pyogenes MGAS10270]; Could be the ATP-dependent specificity component of an ATP-dependent protease.; ATP-dependent protease ATP-binding subunit ClpL 1106914 clpL 6760715 clpL Streptococcus equi subsp. zooepidemicus MGCS10565 ATP-dependent protease ATP-binding subunit ClpL YP_002123437.1 1104821 D 552526 CDS YP_002123438.1 195978194 6760805 complement(1107098..1110109) 1 NC_011134.1 similar to ref|NP_687455.1| cell wall surface anchor family protein [Streptococcus agalactiae 2603V/R]; Unknown, possible adhesin, cognate in GBS has been shown to be immunoprotective in mice.; cell surface protein, RBC-binding protein 1110109 6760805 Sez_1073 Streptococcus equi subsp. zooepidemicus MGCS10565 cell surface protein, RBC-binding protein YP_002123438.1 1107098 R 552526 CDS YP_002123439.1 195978195 6760718 complement(1110471..1111073) 1 NC_011134.1 binds guanine nucleotides; in Escherichia coli depletion results in defective cell division and filamentation; in Bacillus subtilis this gene is essential; ribosome biogenesis GTP-binding protein YsxC 1111073 engB 6760718 engB Streptococcus equi subsp. zooepidemicus MGCS10565 ribosome biogenesis GTP-binding protein YsxC YP_002123439.1 1110471 R 552526 CDS YP_002123440.1 195978196 6760780 complement(1111080..1112309) 1 NC_011134.1 binds and unfolds substrates as part of the ClpXP protease; ATP-dependent protease ATP-binding subunit ClpX 1112309 clpX 6760780 clpX Streptococcus equi subsp. zooepidemicus MGCS10565 ATP-dependent protease ATP-binding subunit ClpX YP_002123440.1 1111080 R 552526 CDS YP_002123441.1 195978197 6760712 complement(1112345..1112515) 1 NC_011134.1 similar to ref|NP_607088.1| hypothetical protein spyM18_0945 [Streptococcus pyogenes MGAS8232]; hypothetical protein 1112515 6760712 Sez_1076 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123441.1 1112345 R 552526 CDS YP_002123442.1 195978198 6762344 complement(1112535..1113035) 1 NC_011134.1 similar to ref|YP_602275.1| Dihydrofolate reductase [Streptococcus pyogenes MGAS10750]; Essential step for de novo glycine and purine synthesis, DNA precursor synthesis, and for the conversion of dUMP to dTMP.; dihydrofolate reductase DhfR 1113035 dhfR 6762344 dhfR Streptococcus equi subsp. zooepidemicus MGCS10565 dihydrofolate reductase DhfR YP_002123442.1 1112535 R 552526 CDS YP_002123443.1 195978199 6760778 complement(1113113..1113952) 1 NC_011134.1 ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived; thymidylate synthase 1113952 thyA 6760778 thyA Streptococcus equi subsp. zooepidemicus MGCS10565 thymidylate synthase YP_002123443.1 1113113 R 552526 CDS YP_002123444.1 195978200 6760957 1114137..1115312 1 NC_011134.1 similar to ref|NP_269080.1| 3-hydroxy-3-methylglutaryl-coenzyme A synthase (HMG-CoA synthase) [Streptococcus pyogenes M1 GAS]; Catalysis of the reaction: acetyl-CoA + H2O + acetoacetyl-CoA = (S)-3-hydroxy-3-methylglutaryl-CoA + CoA.; hydroxymethylglutaryl-CoA synthase 1115312 6760957 Sez_1079 Streptococcus equi subsp. zooepidemicus MGCS10565 hydroxymethylglutaryl-CoA synthase YP_002123444.1 1114137 D 552526 CDS YP_002123445.1 195978201 6762349 1115296..1116582 1 NC_011134.1 similar to ref|NP_607084.1| HMG-CoA reductase [Streptococcus pyogenes MGAS8232]; Converts HMG-CoA to mevalonate.; 3-hydroxy-3-methylglutaryl-CoA reductase 1116582 hmgA 6762349 hmgA Streptococcus equi subsp. zooepidemicus MGCS10565 3-hydroxy-3-methylglutaryl-CoA reductase YP_002123445.1 1115296 D 552526 CDS YP_002123446.1 195978202 6762326 complement(1116866..1117858) 1 NC_011134.1 catalyzes the isomerization of isopentenyl pyrophosphate to dimethylallyl diphosphate; isopentenyl pyrophosphate isomerase 1117858 6762326 Sez_1081 Streptococcus equi subsp. zooepidemicus MGCS10565 isopentenyl pyrophosphate isomerase YP_002123446.1 1116866 R 552526 CDS YP_002123447.1 195978203 6762320 complement(1117861..1118757) 1 NC_011134.1 similar to ref|YP_598351.1| Phosphomevalonate kinase [Streptococcus pyogenes MGAS10270]; Catalysis of the reaction: ATP + (R)-5-phosphomevalonate = ADP + (R)-5-diphosphomevalonate.; phosphomevalonate kinase 1118757 6762320 Sez_1082 Streptococcus equi subsp. zooepidemicus MGCS10565 phosphomevalonate kinase YP_002123447.1 1117861 R 552526 CDS YP_002123448.1 195978204 6762341 complement(1118851..1119795) 1 NC_011134.1 similar to ref|YP_001128674.1| mevalonate diphosphate decarboxylase [Streptococcus pyogenes str. Manfredo]; Catalysis of the reaction: ATP + (R)-5-diphosphomevalonate = ADP + phosphate + isopentenyl diphosphate + CO2.; diphosphomevalonate decarboxylase 1119795 6762341 Sez_1083 Streptococcus equi subsp. zooepidemicus MGCS10565 diphosphomevalonate decarboxylase YP_002123448.1 1118851 R 552526 CDS YP_002123449.1 195978205 6762317 complement(1119777..1120655) 1 NC_011134.1 similar to ref|NP_664399.1| mevalonate kinase [Streptococcus pyogenes MGAS315]; Catalysis of the reaction: ATP + (R)-mevalonate = ADP + (R)-5-phosphomevalonate.; mevalonate kinase Mvk 1120655 mvk 6762317 mvk Streptococcus equi subsp. zooepidemicus MGCS10565 mevalonate kinase Mvk YP_002123449.1 1119777 R 552526 CDS YP_002123450.1 195978206 6762314 complement(1121186..1122898) 1 NC_011134.1 similar to ref|YP_001198771.1| ABC transporter [Streptococcus suis 05ZYH33]; ABC transporter ATP-binding protein/permease 1122898 6762314 Sez_1085 Streptococcus equi subsp. zooepidemicus MGCS10565 ABC transporter ATP-binding protein/permease YP_002123450.1 1121186 R 552526 CDS YP_002123451.1 195978207 6762307 complement(1122939..1123961) 1 NC_011134.1 similar to ref|YP_001200977.1| ABC-type multidrug transport system, ATPase and permease component [Streptococcus suis 98HAH33]; multidrug resistance transport system ATP-binding protein 1123961 6762307 Sez_1086 Streptococcus equi subsp. zooepidemicus MGCS10565 multidrug resistance transport system ATP-binding protein YP_002123451.1 1122939 R 552526 CDS YP_002123452.1 195978208 6762315 complement(1123916..1124671) 1 NC_011134.1 similar to ref|YP_001200977.1| ABC-type multidrug transport system, ATPase and permease component [Streptococcus suis 98HAH33]; multidrug ABC transporter ATPase/permease 1124671 6762315 Sez_1087 Streptococcus equi subsp. zooepidemicus MGCS10565 multidrug ABC transporter ATPase/permease YP_002123452.1 1123916 R 552526 CDS YP_002123453.1 195978209 6762313 1125109..1127115 1 NC_011134.1 similar to ref|YP_060013.1| 5'-nucleotidase [Streptococcus pyogenes MGAS10394]; cell surface 5'-nucleotidase 1127115 6762313 Sez_1088 Streptococcus equi subsp. zooepidemicus MGCS10565 cell surface 5'-nucleotidase YP_002123453.1 1125109 D 552526 CDS YP_002123454.1 195978210 6762293 complement(1127308..1127718) 1 NC_011134.1 cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+); peptide deformylase 1127718 def 6762293 def Streptococcus equi subsp. zooepidemicus MGCS10565 peptide deformylase YP_002123454.1 1127308 R 552526 CDS YP_002123455.1 195978211 6762305 complement(1127850..1129199) 1 NC_011134.1 converts 2-oxoglutarate to glutamate; in Escherichia coli this enzyme plays a role in glutamate synthesis when the cell is under energy restriction; uses NADPH; forms a homohexamer; glutamate dehydrogenase 1129199 gdh 6762305 gdh Streptococcus equi subsp. zooepidemicus MGCS10565 glutamate dehydrogenase YP_002123455.1 1127850 R 552526 CDS YP_002123456.1 195978212 6762300 complement(1129340..1131112) 1 NC_011134.1 similar to ref|YP_001450473.1| permease ATP-binding protein [Streptococcus gordonii str. Challis substr. CH1]; ABC transporter ATP-binding protein/permease 1131112 6762300 Sez_1091 Streptococcus equi subsp. zooepidemicus MGCS10565 ABC transporter ATP-binding protein/permease YP_002123456.1 1129340 R 552526 CDS YP_002123457.1 195978213 6762298 complement(1131112..1132857) 1 NC_011134.1 similar to ref|YP_001200357.1| ABC transporter, ATP-binding protein [Streptococcus suis 98HAH33]; ABC transporter ATP-binding protein/permease 1132857 6762298 Sez_1092 Streptococcus equi subsp. zooepidemicus MGCS10565 ABC transporter ATP-binding protein/permease YP_002123457.1 1131112 R 552526 CDS YP_002123458.1 195978214 6762287 complement(1132962..1134830) 1 NC_011134.1 similar to ref|YP_598341.1| ABC transporter ATP-binding protein uup [Streptococcus pyogenes MGAS10270]; ABC transporter ATPase 1134830 6762287 Sez_1093 Streptococcus equi subsp. zooepidemicus MGCS10565 ABC transporter ATPase YP_002123458.1 1132962 R 552526 CDS YP_002123459.1 195978215 6762291 complement(1134823..1136019) 1 NC_011134.1 catalyzes the addition and repair of the 3'-terminal CCA sequence in tRNA; these proteins belong to the CCA-adding enzyme subfamily 2 which does not have phosphohydrolase activity; tRNA CCA-pyrophosphorylase 1136019 cca 6762291 cca Streptococcus equi subsp. zooepidemicus MGCS10565 tRNA CCA-pyrophosphorylase YP_002123459.1 1134823 R 552526 CDS YP_002123460.1 195978216 6762274 complement(1136138..1136986) 1 NC_011134.1 similar to ref|ZP_00366624.1| COG1307: Uncharacterized protein conserved in bacteria [Streptococcus pyogenes M49 591]; DegV family protein 1136986 6762274 Sez_1095 Streptococcus equi subsp. zooepidemicus MGCS10565 DegV family protein YP_002123460.1 1136138 R 552526 CDS YP_002123461.1 195978217 6762280 complement(1136986..1137399) 1 NC_011134.1 similar to ref|YP_060007.1| Transposase [Streptococcus pyogenes MGAS10394]; transposase 1137399 6762280 Sez_1096 Streptococcus equi subsp. zooepidemicus MGCS10565 transposase YP_002123461.1 1136986 R 552526 CDS YP_002123462.1 195978218 6762276 complement(1137589..1138299) 1 NC_011134.1 similar to ref|ZP_00366628.1| COG1705: Muramidase (flagellum-specific) [Streptococcus pyogenes M49 591]; Hydrolyzes the cell wall of E.faecalis and M.lysodeikticus. May play an important role in cell wall growth and cell separation.; autolysin precursor 1138299 6762276 Sez_1097 Streptococcus equi subsp. zooepidemicus MGCS10565 autolysin precursor YP_002123462.1 1137589 R 552526 CDS YP_002123463.1 195978219 6762272 complement(1138746..1140104) 1 NC_011134.1 similar to ref|ZP_02146542.1| Di- and tricarboxylate transporter [Phaeobacter gallaeciensis BS107]; Responsible For The Uptake Of Citrate In Exchange To The Efflux Of Succinate. Has A Relatively Broad Specificity For C(4)- Dicarboxylates And Tricarboxylates.; di- and tricarboxylate transporters 1140104 citT 6762272 citT Streptococcus equi subsp. zooepidemicus MGCS10565 di- and tricarboxylate transporters YP_002123463.1 1138746 R 552526 CDS YP_002123464.1 195978220 6762270 complement(1140513..1140719) 1 NC_011134.1 similar to ref|ZP_02093443.1| hypothetical protein PEPMIC_00194 [Peptostreptococcus micros ATCC 33270]; hypothetical protein 1140719 6762270 Sez_1099 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123464.1 1140513 R 552526 CDS YP_002123465.1 195978221 6762264 complement(1141191..1141424) 1 NC_011134.1 similar to ref|ZP_02094098.1| hypothetical protein PEPMIC_00856 [Peptostreptococcus micros ATCC 33270]; hypothetical protein 1141424 6762264 Sez_1100 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123465.1 1141191 R 552526 CDS YP_002123466.1 195978222 6762261 complement(1141573..1141782) 1 NC_011134.1 similar to ref|ZP_02091657.1| hypothetical protein FAEPRAM212_01939 [Faecalibacterium prausnitzii M21/2]; hypothetical protein 1141782 6762261 Sez_1101 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123466.1 1141573 R 552526 CDS YP_002123467.1 195978223 6762259 complement(1142342..1142941) 1 NC_011134.1 similar to ref|YP_596450.1| N-acetylmuramidase [Streptococcus pyogenes MGAS9429]; Cognates hydrolyze the cell wall of L.lactis and M.lysodeikticus. Required for cell separation during growth.; N-acetylmuramidase precursor 1142941 6762259 Sez_1102 Streptococcus equi subsp. zooepidemicus MGCS10565 N-acetylmuramidase precursor YP_002123467.1 1142342 R 552526 CDS YP_002123468.1 195978224 6762256 complement(1143045..1143173) 1 NC_011134.1 similar to gb|EDQ65758.1| predicted protein [Physcomitrella patens subsp. patens]; hypothetical protein 1143173 6762256 Sez_1103 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123468.1 1143045 R 552526 CDS YP_002123469.1 195978225 6762253 complement(1143529..1145475) 1 NC_011134.1 similar to ref|NP_269062.1| fructose-specific enzyme II, PTS system BC component [Streptococcus pyogenes M1 GAS]; The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. This system is involved in fructose transport.; PTS system fructose-specific transporter subunit IIABC 1145475 fruA 6762253 fruA Streptococcus equi subsp. zooepidemicus MGCS10565 PTS system fructose-specific transporter subunit IIABC YP_002123469.1 1143529 R 552526 CDS YP_002123470.1 195978226 6762247 complement(1145472..1146383) 1 NC_011134.1 similar to ref|YP_596448.1| 1-phosphofructokinase [Streptococcus pyogenes MGAS9429]; Catalysis of the reaction: ATP + D-tagatose 6-phosphate = ADP + D-tagatose 1,6-bisphosphate.; tagatose-6-phosphate kinase / 1-phosphofructokinase FruK 1146383 fruK 6762247 fruK Streptococcus equi subsp. zooepidemicus MGCS10565 tagatose-6-phosphate kinase / 1-phosphofructokinase FruK YP_002123470.1 1145472 R 552526 CDS YP_002123471.1 195978227 6762244 complement(1146380..1147093) 1 NC_011134.1 similar to ref|NP_269060.1| transcriptional repressor [Streptococcus pyogenes M1 GAS]; Repressor of the glycerol-3-phosphate regulon.; glycerol-3-phosphate regulon repressor GlpR 1147093 glpR 6762244 glpR Streptococcus equi subsp. zooepidemicus MGCS10565 glycerol-3-phosphate regulon repressor GlpR YP_002123471.1 1146380 R 552526 CDS YP_002123472.1 195978228 6762223 complement(1147528..1148451) 1 NC_011134.1 ketopantoate reductase; catalyzes the NADPH reduction of ketopantoate to pantoate; functions in pantothenate (vitamin B5) biosynthesis; 2-dehydropantoate 2-reductase 1148451 6762223 Sez_1107 Streptococcus equi subsp. zooepidemicus MGCS10565 2-dehydropantoate 2-reductase YP_002123472.1 1147528 R 552526 CDS YP_002123473.1 195978229 6762239 complement(1148463..1149521) 1 NC_011134.1 similar to ref|NP_269058.1| regulatory protein [Streptococcus pyogenes M1 GAS]; regulatory protein 1149521 6762239 Sez_1108 Streptococcus equi subsp. zooepidemicus MGCS10565 regulatory protein YP_002123473.1 1148463 R 552526 CDS YP_002123474.1 195978230 6762214 complement(1149653..1150645) 1 NC_011134.1 similar to ref|ZP_00365412.1| COG0492: Thioredoxin reductase [Streptococcus pyogenes M49 591]; Catalysis of the reaction: thioredoxin + NADP+ = thioredoxin disulfide + NADPH + H+.; thioredoxin reductase 1150645 6762214 Sez_1109 Streptococcus equi subsp. zooepidemicus MGCS10565 thioredoxin reductase YP_002123474.1 1149653 R 552526 CDS YP_002123475.1 195978231 6762210 complement(1150645..1151376) 1 NC_011134.1 methylates guanosine-37 in various tRNAs; uses S-adenosyl-L-methionine to transfer methyl group to tRNA; tRNA (guanine-N(1)-)-methyltransferase 1151376 trmD 6762210 trmD Streptococcus equi subsp. zooepidemicus MGCS10565 tRNA (guanine-N(1)-)-methyltransferase YP_002123475.1 1150645 R 552526 CDS YP_002123476.1 195978232 6762231 complement(1151366..1151884) 1 NC_011134.1 Essential for efficient processing of 16S rRNA; 16S rRNA-processing protein RimM 1151884 rimM 6762231 rimM Streptococcus equi subsp. zooepidemicus MGCS10565 16S rRNA-processing protein RimM YP_002123476.1 1151366 R 552526 CDS YP_002123477.1 195978233 6762176 complement(1152264..1153067) 1 NC_011134.1 similar to ref|YP_596865.1| transposase [Streptococcus pyogenes MGAS9429]; transposase IS861 orfB 1153067 6762176 Sez_1112 Streptococcus equi subsp. zooepidemicus MGCS10565 transposase IS861 orfB YP_002123477.1 1152264 R 552526 CDS YP_002123478.1 195978234 6762220 complement(1153091..1153606) 1 NC_011134.1 similar to ref|YP_602677.1| Transposase [Streptococcus pyogenes MGAS10750]; transposase IS861 orfA 1153606 6762220 Sez_1113 Streptococcus equi subsp. zooepidemicus MGCS10565 transposase IS861 orfA YP_002123478.1 1153091 R 552526 CDS YP_002123479.1 195978235 6762217 complement(1154088..1157573) 1 NC_011134.1 similar to ref|ZP_00785378.1| subtilase [Streptococcus agalactiae COH1]; Unknown, has an 115aa domain with similarity to internalin A of Listeria monocytogenes.; hypothetical protein 1157573 6762217 Sez_1114 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123479.1 1154088 R 552526 CDS YP_002123480.1 195978236 6762190 complement(1157827..1158780) 1 NC_011134.1 similar to ref|ZP_00874436.1| Integrase, catalytic region [Streptococcus suis 89/1591]; transposase IS1239 1158780 6762190 Sez_1115 Streptococcus equi subsp. zooepidemicus MGCS10565 transposase IS1239 YP_002123480.1 1157827 R 552526 CDS YP_002123481.1 195978237 6762205 complement(1158849..1159505) 1 NC_011134.1 similar to ref|ZP_02093841.1| hypothetical protein PEPMIC_00596 [Peptostreptococcus micros ATCC 33270]; resolvase/integrase 1159505 6762205 Sez_1116 Streptococcus equi subsp. zooepidemicus MGCS10565 resolvase/integrase YP_002123481.1 1158849 R 552526 CDS YP_002123482.1 195978238 6762207 complement(1159672..1159911) 1 NC_011134.1 similar to ref|ZP_00366185.1| COG1837: Predicted RNA-binding protein (contains KH domain) [Streptococcus pyogenes M49 591]; hypothetical protein 1159911 6762207 Sez_1117 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123482.1 1159672 R 552526 CDS YP_002123483.1 195978239 6762202 complement(1159921..1160166) 1 NC_011134.1 similar to ref|NP_269049.1| 30S ribosomal protein S16 [Streptococcus pyogenes M1 GAS]; In addition to being a ribosomal protein, S16 also has a cation-dependent endonuclease activity.; 30S ribosomal protein S16 1160166 rpsP 6762202 rpsP Streptococcus equi subsp. zooepidemicus MGCS10565 30S ribosomal protein S16 YP_002123483.1 1159921 R 552526 CDS YP_002123484.1 195978240 6762175 complement(1160636..1161172) 1 NC_011134.1 similar to ref|NP_735374.1| hypothetical protein gbs0925 [Streptococcus agalactiae NEM316]; hypothetical protein 1161172 6762175 Sez_1119 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123484.1 1160636 R 552526 CDS YP_002123485.1 195978241 6762173 complement(1161246..1162469) 1 NC_011134.1 similar to ref|YP_282009.1| ABC transporter permease [Streptococcus pyogenes MGAS5005]; ABC transporter permease 1162469 6762173 Sez_1120 Streptococcus equi subsp. zooepidemicus MGCS10565 ABC transporter permease YP_002123485.1 1161246 R 552526 CDS YP_002123486.1 195978242 6762185 complement(1162481..1163191) 1 NC_011134.1 similar to ref|YP_280095.1| ABC transporter ATP-binding protein [Streptococcus pyogenes MGAS6180]; ABC transporter ATP-binding protein 1163191 6762185 Sez_1121 Streptococcus equi subsp. zooepidemicus MGCS10565 ABC transporter ATP-binding protein YP_002123486.1 1162481 R 552526 CDS YP_002123487.1 195978243 6762177 complement(1163191..1164453) 1 NC_011134.1 similar to emb|CAM30488.1| exported protein [Streptococcus pyogenes str. Manfredo]; hypothetical protein 1164453 6762177 Sez_1122 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123487.1 1163191 R 552526 CDS YP_002123488.1 195978244 6762154 complement(1164709..1167912) 1 NC_011134.1 four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate; CarB is responsible for the amidotransferase activity; carbamoyl phosphate synthase large subunit 1167912 carB 6762154 carB Streptococcus equi subsp. zooepidemicus MGCS10565 carbamoyl phosphate synthase large subunit YP_002123488.1 1164709 R 552526 CDS YP_002123489.1 195978245 6762155 complement(1168304..1169440) 1 NC_011134.1 catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers; carbamoyl phosphate synthase small subunit 1169440 carA 6762155 carA Streptococcus equi subsp. zooepidemicus MGCS10565 carbamoyl phosphate synthase small subunit YP_002123489.1 1168304 R 552526 CDS YP_002123490.1 195978246 6762147 complement(1169418..1170353) 1 NC_011134.1 catalyzes the transfer of the carbamoyl moiety from carbamoyl phosphate to L- aspartate in pyrimidine biosynthesis; aspartate carbamoyltransferase 1170353 pyrB 6762147 pyrB Streptococcus equi subsp. zooepidemicus MGCS10565 aspartate carbamoyltransferase YP_002123490.1 1169418 R 552526 CDS YP_002123491.1 195978247 6762146 complement(1170411..1171670) 1 NC_011134.1 similar to ref|YP_001128709.1| uracil permease [Streptococcus pyogenes str. Manfredo]; Transport of uracil in the cell.; uracil permease PyrP 1171670 pyrP 6762146 pyrP Streptococcus equi subsp. zooepidemicus MGCS10565 uracil permease PyrP YP_002123491.1 1170411 R 552526 CDS YP_002123492.1 195978248 6762142 complement(1171686..1172207) 1 NC_011134.1 regulates pyrimidine biosynthesis by binding to the mRNA of the pyr genes, also has been shown to have uracil phosphoribosyltransferase activity; bifunctional pyrimidine regulatory protein PyrR/uracil phosphoribosyltransferase 1172207 pyrR 6762142 pyrR Streptococcus equi subsp. zooepidemicus MGCS10565 bifunctional pyrimidine regulatory protein PyrR/uracil phosphoribosyltransferase YP_002123492.1 1171686 R 552526 CDS YP_002123493.1 195978249 6762134 1172566..1173183 1 NC_011134.1 similar to ref|NP_815585.1| hypothetical protein EF1903 [Enterococcus faecalis V583]; membrane-associated alkaline phosphatase 1173183 6762134 Sez_1128 Streptococcus equi subsp. zooepidemicus MGCS10565 membrane-associated alkaline phosphatase YP_002123493.1 1172566 D 552526 CDS YP_002123494.1 195978250 6762131 complement(1173264..1174154) 1 NC_011134.1 similar to ref|YP_059974.1| Ribosomal large subunit pseudouridine synthase D [Streptococcus pyogenes MGAS10394]; Responsible For Synthesis Of Pseudouridine From Uracil At Positions 1911, 1915 And 1917 In 23s Ribosomal RNA.; ribosomal large subunit pseudouridine synthase D 1174154 6762131 Sez_1129 Streptococcus equi subsp. zooepidemicus MGCS10565 ribosomal large subunit pseudouridine synthase D YP_002123494.1 1173264 R 552526 CDS YP_002123495.1 195978251 6762129 complement(1174144..1174581) 1 NC_011134.1 lipoprotein signal peptidase; integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis; lipoprotein signal peptidase 1174581 lspA 6762129 lspA Streptococcus equi subsp. zooepidemicus MGCS10565 lipoprotein signal peptidase YP_002123495.1 1174144 R 552526 CDS YP_002123496.1 195978252 6762128 complement(1174623..1174757) 1 NC_011134.1 hypothetical protein 1174757 6762128 Sez_1131 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123496.1 1174623 R 552526 CDS YP_002123497.1 195978253 6762127 complement(1174831..1175760) 1 NC_011134.1 similar to ref|YP_280085.1| transcriptional regulator, LysR family [Streptococcus pyogenes MGAS6180]; cysteine and methionine metabolism regulator 1175760 6762127 Sez_1132 Streptococcus equi subsp. zooepidemicus MGCS10565 cysteine and methionine metabolism regulator YP_002123497.1 1174831 R 552526 CDS YP_002123498.1 195978254 6762097 complement(1176167..1176436) 1 NC_011134.1 involved in the peptidyltransferase reaction during translation; 50S ribosomal protein L27 1176436 rpmA 6762097 rpmA Streptococcus equi subsp. zooepidemicus MGCS10565 50S ribosomal protein L27 YP_002123498.1 1176167 R 552526 CDS YP_002123499.1 195978255 6762117 complement(1176482..1176814) 1 NC_011134.1 similar to ref|YP_001450118.1| ribosomal protein [Streptococcus gordonii str. Challis substr. CH1]; hypothetical protein 1176814 6762117 Sez_1134 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123499.1 1176482 R 552526 CDS YP_002123500.1 195978256 6762089 complement(1176827..1177141) 1 NC_011134.1 similar to ref|NP_269034.1| 50S ribosomal protein L21 [Streptococcus pyogenes M1 GAS]; This protein binds to 23S ribosomal RNA in the presence of protein L20.; 50S ribosomal protein L21 1177141 rplU 6762089 rplU Streptococcus equi subsp. zooepidemicus MGCS10565 50S ribosomal protein L21 YP_002123500.1 1176827 R 552526 CDS YP_002123501.1 195978257 6762108 complement(1177371..1178564) 1 NC_011134.1 similar to ref|YP_280081.1| capsule biosynthesis protein [Streptococcus pyogenes MGAS6180]; capsule biosynthesis protein CapA-like 1178564 capA 6762108 capA Streptococcus equi subsp. zooepidemicus MGCS10565 capsule biosynthesis protein CapA-like YP_002123501.1 1177371 R 552526 CDS YP_002123502.1 195978258 6762075 1178796..1179446 1 NC_011134.1 similar to ref|NP_607417.1| hypothetical protein spyM18_1310 [Streptococcus pyogenes MGAS8232]; lipoprotein 1179446 6762075 Sez_1137 Streptococcus equi subsp. zooepidemicus MGCS10565 lipoprotein YP_002123502.1 1178796 D 552526 CDS YP_002123503.1 195978259 6762072 complement(1179744..1180964) 1 NC_011134.1 similar to ref|YP_001449814.1| permease [Streptococcus gordonii str. Challis substr. CH1] gb|AAG32545.1| Dsg [Streptococcus gordonii]; macrolide-efflux protein 1180964 6762072 Sez_1138 Streptococcus equi subsp. zooepidemicus MGCS10565 macrolide-efflux protein YP_002123503.1 1179744 R 552526 CDS YP_002123504.1 195978260 6762087 complement(1181036..1181209) 1 NC_011134.1 hypothetical protein 1181209 6762087 Sez_1139 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123504.1 1181036 R 552526 CDS YP_002123505.1 195978261 6762085 complement(1181509..1182285) 1 NC_011134.1 similar to ref|ZP_01821646.1| transcriptional activator, Rgg/GadR/MutR family protein, C-terminal domain [Streptococcus pneumoniae SP6-BS73]; positive transcriptional regulator MutR family 1182285 6762085 Sez_1140 Streptococcus equi subsp. zooepidemicus MGCS10565 positive transcriptional regulator MutR family YP_002123505.1 1181509 R 552526 CDS YP_002123506.1 195978262 6762056 complement(1184565..1185767) 1 NC_011134.1 in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins; 30S ribosomal protein S1 1185767 rpsA 6762056 rpsA Streptococcus equi subsp. zooepidemicus MGCS10565 30S ribosomal protein S1 YP_002123506.1 1184565 R 552526 CDS YP_002123507.1 195978263 6761144 complement(1186146..1186376) 1 NC_011134.1 similar to ref|YP_602302.1| hypothetical cytosolic protein [Streptococcus pyogenes MGAS10750]; hypothetical protein 1186376 6761144 Sez_1145 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123507.1 1186146 R 552526 CDS YP_002123508.1 195978264 6762064 complement(1186444..1187466) 1 NC_011134.1 catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids; branched-chain amino acid aminotransferase 1187466 ilvE 6762064 ilvE Streptococcus equi subsp. zooepidemicus MGCS10565 branched-chain amino acid aminotransferase YP_002123508.1 1186444 R 552526 CDS YP_002123509.1 195978265 6762060 complement(1187567..1190026) 1 NC_011134.1 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling; DNA topoisomerase IV subunit A 1190026 parC 6762060 parC Streptococcus equi subsp. zooepidemicus MGCS10565 DNA topoisomerase IV subunit A YP_002123509.1 1187567 R 552526 CDS YP_002123510.1 195978266 6762055 complement(1190500..1191363) 1 NC_011134.1 similar to ref|YP_001128646.1| hypothetical protein SpyM51096 [Streptococcus pyogenes str. Manfredo]; hypothetical protein 1191363 6762055 Sez_1148 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123510.1 1190500 R 552526 CDS YP_002123511.1 195978267 6762022 complement(1191417..1193366) 1 NC_011134.1 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling; DNA topoisomerase IV subunit B 1193366 parE 6762022 parE Streptococcus equi subsp. zooepidemicus MGCS10565 DNA topoisomerase IV subunit B YP_002123511.1 1191417 R 552526 CDS YP_002123512.1 195978268 6762049 1193499..1194146 1 NC_011134.1 involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsX; glycerol-3-phosphate acyltransferase PlsY 1194146 6762049 Sez_1150 Streptococcus equi subsp. zooepidemicus MGCS10565 glycerol-3-phosphate acyltransferase PlsY YP_002123512.1 1193499 D 552526 CDS YP_002123513.1 195978269 6762028 complement(1194200..1195612) 1 NC_011134.1 catalyzes the formation of N-carbamoyl-L-aspartate from (S)-dihydroorotate in pyrimidine biosynthesis; dihydroorotase 1195612 pyrC 6762028 pyrC Streptococcus equi subsp. zooepidemicus MGCS10565 dihydroorotase YP_002123513.1 1194200 R 552526 CDS YP_002123514.1 195978270 6761979 complement(1195707..1196360) 1 NC_011134.1 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine; uracil-DNA glycosylase 1196360 ung 6761979 ung Streptococcus equi subsp. zooepidemicus MGCS10565 uracil-DNA glycosylase YP_002123514.1 1195707 R 552526 CDS YP_002123515.1 195978271 6762042 complement(1196372..1196746) 1 NC_011134.1 similar to gb|EDK88467.1| possible acetyltransferase [Fusobacterium nucleatum subsp.; acetyltransferase 1196746 6762042 Sez_1153 Streptococcus equi subsp. zooepidemicus MGCS10565 acetyltransferase YP_002123515.1 1196372 R 552526 CDS YP_002123516.1 195978272 6762033 complement(1196910..1197563) 1 NC_011134.1 similar to ref|NP_664424.1| ABC transporter (permease) [Streptococcus pyogenes MGAS315]; Part of a binding-protein-dependent transport system. Probably responsible for the translocation of the substrate across the membrane.; amino-acid ABC transporter permease 1197563 6762033 Sez_1154 Streptococcus equi subsp. zooepidemicus MGCS10565 amino-acid ABC transporter permease YP_002123516.1 1196910 R 552526 CDS YP_002123517.1 195978273 6762026 complement(1197591..1198475) 1 NC_011134.1 similar to ref|NP_269099.1| ABC transporter (binding protein) [Streptococcus pyogenes M1 GAS]; Probably part of a binding-protein-dependent transport system.; cystine ABC transporter substrate-binding lipoprotein precursor 1198475 6762026 Sez_1155 Streptococcus equi subsp. zooepidemicus MGCS10565 cystine ABC transporter substrate-binding lipoprotein precursor YP_002123517.1 1197591 R 552526 CDS YP_002123518.1 195978274 6762015 complement(1198577..1200031) 1 NC_011134.1 catalyzes the hydrolysis of a monocarboxylic acid amid to form a monocarboxylate and ammonia; amidase 1200031 6762015 Sez_1156 Streptococcus equi subsp. zooepidemicus MGCS10565 amidase YP_002123518.1 1198577 R 552526 CDS YP_002123519.1 195978275 6762010 complement(1200263..1200982) 1 NC_011134.1 similar to ref|ZP_00789806.1| acetyltransferase, GNAT family [Streptococcus agalactiae 515]; GNAT family acetyltransferase 1200982 6762010 Sez_1157 Streptococcus equi subsp. zooepidemicus MGCS10565 GNAT family acetyltransferase YP_002123519.1 1200263 R 552526 CDS YP_002123520.1 195978276 6761974 complement(1201057..1201692) 1 NC_011134.1 similar to ref|NP_721600.1| orotate phosphoribosyltransferase [Streptococcus mutans UA159]; Catalysis of the reaction: orotidine 5'-phosphate + diphosphate = orotate + 5-phospho-alpha-D-ribose 1-diphosphate.; orotate phosphoribosyltransferase PyrE 1201692 pyrE 6761974 pyrE Streptococcus equi subsp. zooepidemicus MGCS10565 orotate phosphoribosyltransferase PyrE YP_002123520.1 1201057 R 552526 CDS YP_002123521.1 195978277 6762001 complement(1201752..1202444) 1 NC_011134.1 type 1 subfamily; involved in last step of pyrimidine biosynthesis; converts orotidine 5'-phosphate to UMP and carbon dioxide; OMP decarboxylase; OMPDCase; OMPdecase; orotidine 5'-phosphate decarboxylase 1202444 pyrF 6762001 pyrF Streptococcus equi subsp. zooepidemicus MGCS10565 orotidine 5'-phosphate decarboxylase YP_002123521.1 1201752 R 552526 CDS YP_002123522.1 195978278 6761999 complement(1203061..1203510) 1 NC_011134.1 similar to ref|YP_001128656.1| hypothetical protein SpyM51106 [Streptococcus pyogenes str. Manfredo]; hypothetical protein 1203510 6761999 Sez_1160 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123522.1 1203061 R 552526 CDS YP_002123523.1 195978279 6761978 1203849..1204757 1 NC_011134.1 similar to ref|YP_596489.1| transcriptional regulators, LysR family [Streptococcus pyogenes MGAS9429]; HTH-type transcriptional regulator 1204757 6761978 Sez_1161 Streptococcus equi subsp. zooepidemicus MGCS10565 HTH-type transcriptional regulator YP_002123523.1 1203849 D 552526 CDS YP_002123524.1 195978280 6761993 complement(1204888..1205706) 1 NC_011134.1 similar to ref|YP_060035.1| Histidine protein kinase [Streptococcus pyogenes MGAS10394]; histidine protein kinase 1205706 6761993 Sez_1162 Streptococcus equi subsp. zooepidemicus MGCS10565 histidine protein kinase YP_002123524.1 1204888 R 552526 CDS YP_002123525.1 195978281 6761985 complement(1205764..1206573) 1 NC_011134.1 catalyzes the formation of a purine and ribose phosphate from a purine nucleoside; in E. coli this enzyme functions in xanthosine degradation; purine nucleoside phosphorylase 1206573 punA 6761985 punA Streptococcus equi subsp. zooepidemicus MGCS10565 purine nucleoside phosphorylase YP_002123525.1 1205764 R 552526 CDS YP_002123526.1 195978282 6761965 complement(1206787..1207998) 1 NC_011134.1 catalyzes the transfer of phosphate between the C1 and C5 carbons of pentose; phosphopentomutase 1207998 deoB 6761965 deoB Streptococcus equi subsp. zooepidemicus MGCS10565 phosphopentomutase YP_002123526.1 1206787 R 552526 CDS YP_002123527.1 195978283 6761977 complement(1208076..1208759) 1 NC_011134.1 Catalyzes D-ribose 5-phosphate --> D-ribulose 5-phosphate in the nonoxidative branch of the pentose phosphate pathway; ribose-5-phosphate isomerase A 1208759 rpiA 6761977 rpiA Streptococcus equi subsp. zooepidemicus MGCS10565 ribose-5-phosphate isomerase A YP_002123527.1 1208076 R 552526 CDS YP_002123528.1 195978284 6761959 complement(1208834..1208989) 1 NC_011134.1 hypothetical protein 1208989 6761959 Sez_1166 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123528.1 1208834 R 552526 CDS YP_002123529.1 195978285 6761972 complement(1209193..1209507) 1 NC_011134.1 similar to ref|YP_001035335.1| hypothetical protein SSA_1387 [Streptococcus sanguinis SK36]; hypothetical protein 1209507 6761972 Sez_1167 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123529.1 1209193 R 552526 CDS YP_002123530.1 195978286 6761968 complement(1209514..1210185) 1 NC_011134.1 hypothetical protein 1210185 6761968 Sez_1168 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123530.1 1209514 R 552526 CDS YP_002123531.1 195978287 6761964 complement(1210213..1210893) 1 NC_011134.1 hypothetical protein 1210893 6761964 Sez_1169 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123531.1 1210213 R 552526 CDS YP_002123532.1 195978288 6761961 complement(1210921..1211559) 1 NC_011134.1 hypothetical protein 1211559 6761961 Sez_1170 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123532.1 1210921 R 552526 CDS YP_002123533.1 195978289 6761951 complement(1211626..1212306) 1 NC_011134.1 hypothetical protein 1212306 6761951 Sez_1171 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123533.1 1211626 R 552526 CDS YP_002123534.1 195978290 6761936 complement(1212306..1213904) 1 NC_011134.1 similar to ref|YP_850136.1| hypothetical protein lwe1939 [Listeria welshimeri serovar 6b str. SLCC5334]; hypothetical protein 1213904 6761936 Sez_1172 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123534.1 1212306 R 552526 CDS YP_002123535.1 195978291 6761931 complement(1213906..1214238) 1 NC_011134.1 hypothetical protein 1214238 6761931 Sez_1173 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123535.1 1213906 R 552526 CDS YP_002123536.1 195978292 6761942 complement(1214243..1214557) 1 NC_011134.1 hypothetical protein 1214557 6761942 Sez_1174 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123536.1 1214243 R 552526 CDS YP_002123537.1 195978293 6761939 1215018..1216394 1 NC_011134.1 in Escherichia coli this protein is involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2-thiouridine, which is found in the wobble position of some tRNAs and affects ribosomal frameshifting; shows potassium-dependent dimerization and GTP hydrolysis; also involved in regulation of glutamate-dependent acid resistance and activation of gadE; tRNA modification GTPase TrmE 1216394 trmE 6761939 trmE Streptococcus equi subsp. zooepidemicus MGCS10565 tRNA modification GTPase TrmE YP_002123537.1 1215018 D 552526 CDS YP_002123538.1 195978294 6761908 complement(1218149..1218751) 1 NC_011134.1 similar to ref|NP_269235.1| NADH dehydrogenase [Streptococcus pyogenes M1 GAS]; Catalysis of the reaction: 5,6,7,8-tetrahydropteridine + NAD(P)+ = a 6,7-dihydropteridine + NAD(P)H + H.; oxygen-insensitive NAD(P)H nitroreductase / dihydropteridine reductase 1218751 6761908 Sez_1178 Streptococcus equi subsp. zooepidemicus MGCS10565 oxygen-insensitive NAD(P)H nitroreductase / dihydropteridine reductase YP_002123538.1 1218149 R 552526 CDS YP_002123539.1 195978295 6761921 complement(1218879..1220663) 1 NC_011134.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision; excinuclease ABC subunit C 1220663 uvrC 6761921 uvrC Streptococcus equi subsp. zooepidemicus MGCS10565 excinuclease ABC subunit C YP_002123539.1 1218879 R 552526 CDS YP_002123540.1 195978296 6761896 complement(1220916..1221953) 1 NC_011134.1 similar to ref|ZP_00784614.1| iron ABC transporter, iron-binding protein [Streptococcus agalactiae COH1]; Required For The Activity Of The Bacterial Periplasmic Transport System Of Putrescine And Spermidine. Polyamine Binding Protein.; ferric iron ABC transporter iron-binding protein 1221953 6761896 Sez_1180 Streptococcus equi subsp. zooepidemicus MGCS10565 ferric iron ABC transporter iron-binding protein YP_002123540.1 1220916 R 552526 CDS YP_002123541.1 195978297 6761894 complement(1221950..1222735) 1 NC_011134.1 similar to ref|NP_688934.1| DNA-binding response regulator [Streptococcus agalactiae 2603V/R]; Member Of The Two-Component Regulatory System Atos/Atoc Involved In The Transcriptional Regulation Of The Ato Genes For Acetoacetate Metabolism. Also An Inhibitor Of Polyamine Biosynthesis.; TCS response regulator YesN-like 1222735 yesN 6761894 yesN Streptococcus equi subsp. zooepidemicus MGCS10565 TCS response regulator YesN-like YP_002123541.1 1221950 R 552526 CDS YP_002123542.1 195978298 6761900 complement(1224545..1225333) 1 NC_011134.1 similar to ref|ZP_00780193.1| PTS system, IID component [Streptococcus agalactiae 18RS21]; The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. This system is involved in mannose transport.; mannose permease IID component ManZ 1225333 manZ 6761900 manZ Streptococcus equi subsp. zooepidemicus MGCS10565 mannose permease IID component ManZ YP_002123542.1 1224545 R 552526 CDS YP_002123543.1 195978299 6761876 complement(1225369..1226178) 1 NC_011134.1 similar to ref|YP_060120.1| PTS system, mannose/fructose family IIC component [Streptococcus pyogenes MGAS10394]; The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. This system is involved in mannose transport.; mannose permease IIC component ManY 1226178 manY 6761876 manY Streptococcus equi subsp. zooepidemicus MGCS10565 mannose permease IIC component ManY YP_002123543.1 1225369 R 552526 CDS YP_002123544.1 195978300 6761895 complement(1226196..1226687) 1 NC_011134.1 similar to ref|ZP_00784628.1| PTS system, IIB component [Streptococcus agalactiae COH1]; PTS system mannose/fructose family transporter subunit IIB 1226687 6761895 Sez_1186 Streptococcus equi subsp. zooepidemicus MGCS10565 PTS system mannose/fructose family transporter subunit IIB YP_002123544.1 1226196 R 552526 CDS YP_002123545.1 195978301 6761892 complement(1226702..1227220) 1 NC_011134.1 similar to ref|YP_602425.1| PTS system, mannose/fructose family IIA component [Streptococcus pyogenes MGAS10750]; PTS system mannose/fructose family transporter subunit IIA 1227220 6761892 Sez_1187 Streptococcus equi subsp. zooepidemicus MGCS10565 PTS system mannose/fructose family transporter subunit IIA YP_002123545.1 1226702 R 552526 CDS YP_002123546.1 195978302 6761886 complement(1227471..1228508) 1 NC_011134.1 similar to ref|YP_001128544.1| hypothetical protein SpyM50987 [Streptococcus pyogenes str. Manfredo]; hypothetical protein 1228508 6761886 Sez_1188 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123546.1 1227471 R 552526 CDS YP_002123547.1 195978303 6761882 complement(1228777..1229271) 1 NC_011134.1 this stereospecific enzymes reduces the R isomer of methionine sulfoxide while MsrA reduces the S form; provides protection against oxidative stress; methionine sulfoxide reductase B 1229271 msrB 6761882 msrB Streptococcus equi subsp. zooepidemicus MGCS10565 methionine sulfoxide reductase B YP_002123547.1 1228777 R 552526 CDS YP_002123548.1 195978304 6761878 complement(1229247..1229384) 1 NC_011134.1 hypothetical protein 1229384 6761878 Sez_1190 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123548.1 1229247 R 552526 CDS YP_002123549.1 195978305 6761856 complement(1229739..1231571) 1 NC_011134.1 binds to the ribosome on the universally-conserved alpha-sarcin loop; GTP-binding protein LepA 1231571 lepA 6761856 lepA Streptococcus equi subsp. zooepidemicus MGCS10565 GTP-binding protein LepA YP_002123549.1 1229739 R 552526 CDS YP_002123550.1 195978306 6761838 complement(1232028..1232204) 1 NC_011134.1 hypothetical protein 1232204 6761838 Sez_1192 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123550.1 1232028 R 552526 CDS YP_002123551.1 195978307 6761857 complement(1232657..1232998) 1 NC_011134.1 similar to ref|YP_803634.1| Gene info Predicted prebacteriocin [Pediococcus pentosaceus ATCC 25745]; Bacteriocin; bacteriocin 1232998 6761857 Sez_1194 Streptococcus equi subsp. zooepidemicus MGCS10565 bacteriocin YP_002123551.1 1232657 R 552526 CDS YP_002123552.1 195978308 6761840 complement(1232980..1233165) 1 NC_011134.1 similar to gb|ABD60751.1| class IIa sec-dependent bacteriocin [Enterococcus faecium]; Bacteriocin; bacteriocin 1233165 6761840 Sez_1195 Streptococcus equi subsp. zooepidemicus MGCS10565 bacteriocin YP_002123552.1 1232980 R 552526 CDS YP_002123553.1 195978309 6761851 1233380..1233613 1 NC_011134.1 similar to ref|ZP_01821306.1| Bacteriocin processing peptidase / Bacteriocin export ABC transporter [Streptococcus pneumoniae SP6-BS73]; Involved in the export process of a bacteriocin lactococcin.; lactococcin transport/processing ATP-binding protein LcnC-like 1233613 lcnC 6761851 lcnC Streptococcus equi subsp. zooepidemicus MGCS10565 lactococcin transport/processing ATP-binding protein LcnC-like YP_002123553.1 1233380 D 552526 CDS YP_002123554.1 195978310 6761835 1233580..1233867 1 NC_011134.1 similar to ref|ZP_01823865.1| hypothetical protein CGSSp9BS68_01433 [Streptococcus pneumoniae SP9-BS68]; ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain [Defense mechanisms].; bacteriocin processing peptidase 1233867 6761835 Sez_1197 Streptococcus equi subsp. zooepidemicus MGCS10565 bacteriocin processing peptidase YP_002123554.1 1233580 D 552526 CDS YP_002123555.1 195978311 6761845 1235337..1235492 1 NC_011134.1 similar to ref|ZP_01817231.1| peptide pheromone BlpC [Streptococcus pneumoniae SP3-BS71]; BlpC bacteriocin-like peptide 1235492 blpC 6761845 blpC Streptococcus equi subsp. zooepidemicus MGCS10565 BlpC bacteriocin-like peptide YP_002123555.1 1235337 D 552526 CDS YP_002123556.1 195978312 6761820 complement(1235674..1235964) 1 NC_011134.1 similar to ref|YP_001200659.1| transposase of IS200 family [Streptococcus suis 98HAH33]; transposase of IS200 family 1235964 6761820 Sez_1201 Streptococcus equi subsp. zooepidemicus MGCS10565 transposase of IS200 family YP_002123556.1 1235674 R 552526 CDS YP_002123557.1 195978313 6761833 complement(1236426..1236899) 1 NC_011134.1 similar to ref|YP_001198456.1| transposase of IS200 family [Streptococcus suis 05ZYH33]; transposase IS200 Family 1236899 6761833 Sez_1202 Streptococcus equi subsp. zooepidemicus MGCS10565 transposase IS200 Family YP_002123557.1 1236426 R 552526 CDS YP_002123558.1 195978314 6762243 complement(1236962..1237099) 1 NC_011134.1 hypothetical protein 1237099 6762243 Sez_1203 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123558.1 1236962 R 552526 CDS YP_002123559.1 195978315 6762099 complement(1237177..1237557) 1 NC_011134.1 present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulates GTPase activity of translation factors; 50S ribosomal protein L7/L12 1237557 rplL 6762099 rplL Streptococcus equi subsp. zooepidemicus MGCS10565 50S ribosomal protein L7/L12 YP_002123559.1 1237177 R 552526 CDS YP_002123560.1 195978316 6762213 complement(1237607..1238107) 1 NC_011134.1 binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit; 50S ribosomal protein L10 1238107 rplJ 6762213 rplJ Streptococcus equi subsp. zooepidemicus MGCS10565 50S ribosomal protein L10 YP_002123560.1 1237607 R 552526 CDS YP_002123561.1 195978317 6762193 complement(1238397..1239044) 1 NC_011134.1 similar to ref|YP_280215.1| hypothetical membrane spanning protein [Streptococcus pyogenes MGAS6180]; hypothetical protein 1239044 6762193 Sez_1206 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123561.1 1238397 R 552526 CDS YP_002123562.1 195978318 6762174 complement(1239041..1239808) 1 NC_011134.1 similar to ref|YP_602413.1| Haloacid dehalogenase-like hydrolase [Streptococcus pyogenes MGAS10750]; Predicted to act in N-acetylglucosamine utilization subsystem.; hydrolase HAD superfamily 1239808 6762174 Sez_1207 Streptococcus equi subsp. zooepidemicus MGCS10565 hydrolase HAD superfamily YP_002123562.1 1239041 R 552526 CDS YP_002123563.1 195978319 6762209 complement(1239808..1240560) 1 NC_011134.1 similar to ref|YP_282129.1| acyl-acyl carrier protein thioesterase [Streptococcus pyogenes MGAS5005]; acyl-ACP thioesterase 1240560 6762209 Sez_1208 Streptococcus equi subsp. zooepidemicus MGCS10565 acyl-ACP thioesterase YP_002123563.1 1239808 R 552526 CDS YP_002123564.1 195978320 6762159 complement(1240571..1241701) 1 NC_011134.1 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III; coproporphyrinogen III oxidase 1241701 6762159 Sez_1209 Streptococcus equi subsp. zooepidemicus MGCS10565 coproporphyrinogen III oxidase YP_002123564.1 1240571 R 552526 CDS YP_002123565.1 195978321 6762237 complement(1241768..1242454) 1 NC_011134.1 similar to ref|ZP_00875329.1| GCN5-related N-acetyltransferase [Streptococcus suis 89/1591]; acetyltransferase GNAT Family 1242454 6762237 Sez_1210 Streptococcus equi subsp. zooepidemicus MGCS10565 acetyltransferase GNAT Family YP_002123565.1 1241768 R 552526 CDS YP_002123566.1 195978322 6762194 complement(1242488..1243840) 1 NC_011134.1 catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; phosphoglucosamine mutase 1243840 glmM 6762194 glmM Streptococcus equi subsp. zooepidemicus MGCS10565 phosphoglucosamine mutase YP_002123566.1 1242488 R 552526 CDS YP_002123567.1 195978323 6760434 complement(1243892..1244848) 1 NC_011134.1 similar to ref|NP_664474.1| hypothetical protein SpyM3_0670 [Streptococcus pyogenes MGAS315]; hypothetical protein 1244848 6760434 Sez_1212 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123567.1 1243892 R 552526 CDS YP_002123568.1 195978324 6760432 complement(1244845..1245696) 1 NC_011134.1 similar to ref|YP_001128553.1| hypothetical protein SpyM50998 [Streptococcus pyogenes str. Manfredo]; hypothetical protein 1245696 6760432 Sez_1213 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123568.1 1244845 R 552526 CDS YP_002123569.1 195978325 6760426 1247140..1247928 1 NC_011134.1 similar to ref|YP_598485.1| CobB/CobQ-like glutamine amidotransferase domain [Streptococcus pyogenes MGAS10270]; cobyric acid synthase 1247928 6760426 Sez_1216 Streptococcus equi subsp. zooepidemicus MGCS10565 cobyric acid synthase YP_002123569.1 1247140 D 552526 CDS YP_002123570.1 195978326 6760424 complement(1248384..1249373) 1 NC_011134.1 similar to ref|NP_269204.1| lipoate-protein ligase [Streptococcus pyogenes M1 GAS]; Catalyzes both the ATP-dependent activation of lipoate to lipoyl-AMP and the transfer of the activated lipoyl on the lipoate-dependent enzymes. Creates an amide linkage that joins the free carboxyl group of lipoic acid to the epsilon-amino group of a specific lysine residue in lipoyl domain of apoproteins.; lipoate-protein ligase A LplA 1249373 lplA 6760424 lplA Streptococcus equi subsp. zooepidemicus MGCS10565 lipoate-protein ligase A LplA YP_002123570.1 1248384 R 552526 CDS YP_002123571.1 195978327 6760422 1249363..1249515 1 NC_011134.1 hypothetical protein 1249515 6760422 Sez_1218 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123571.1 1249363 D 552526 CDS YP_002123572.1 195978328 6760420 complement(1249608..1251377) 1 NC_011134.1 similar to ref|YP_598482.1| Dihydrolipoamide dehydrogenase [Streptococcus pyogenes MGAS10270]; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components:pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).; dihydrolipoyl dehydrogenase LpdA 1251377 lpdA 6760420 lpdA Streptococcus equi subsp. zooepidemicus MGCS10565 dihydrolipoyl dehydrogenase LpdA YP_002123572.1 1249608 R 552526 CDS YP_002123573.1 195978329 6760418 complement(1251590..1252996) 1 NC_011134.1 similar to ref|NP_607148.1| branched-chain alpha-keto acid dehydrogenase subunit E2 [Streptococcus pyogenes MGAS8232]; The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and Co(2). It contains multiple copies of three enzymatic components: 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3).; branched-chain alpha-keto acid dehydrogenase E2 subunit 1252996 acoC 6760418 acoC Streptococcus equi subsp. zooepidemicus MGCS10565 branched-chain alpha-keto acid dehydrogenase E2 subunit YP_002123573.1 1251590 R 552526 CDS YP_002123574.1 195978330 6760411 complement(1253120..1254118) 1 NC_011134.1 similar to ref|NP_269200.1| acetoin dehydrogenase (TPP-dependent) beta chain [Streptococcus pyogenes M1 GAS]; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components:pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).; pyruvate dehydrogenase E1 component subunit beta PdhB 1254118 pdhB 6760411 pdhB Streptococcus equi subsp. zooepidemicus MGCS10565 pyruvate dehydrogenase E1 component subunit beta PdhB YP_002123574.1 1253120 R 552526 CDS YP_002123575.1 195978331 6760408 complement(1254198..1255178) 1 NC_011134.1 similar to ref|NP_802454.1| acetoin dehydrogenase (TPP-dependent) alpha chain [Streptococcus pyogenes SSI-1]; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components:pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).; pyruvate dehydrogenase E1 component subunit alpha 1255178 pdhA 6760408 pdhA Streptococcus equi subsp. zooepidemicus MGCS10565 pyruvate dehydrogenase E1 component subunit alpha YP_002123575.1 1254198 R 552526 CDS YP_002123576.1 195978332 6760406 complement(1255672..1257582) 1 NC_011134.1 similar to ref|YP_001128561.1| ABC transporter ATP-binding protein [Streptococcus pyogenes str. Manfredo]; Facilitated transport; ABC transporter ATP-binding protein 1257582 6760406 Sez_1223 Streptococcus equi subsp. zooepidemicus MGCS10565 ABC transporter ATP-binding protein YP_002123576.1 1255672 R 552526 CDS YP_002123577.1 195978333 6760404 complement(1257693..1257980) 1 NC_011134.1 similar to ref|ZP_00365872.1| hypothetical protein SpyoM01000868 [Streptococcus pyogenes M49 591]; hypothetical protein 1257980 6760404 Sez_1224 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123577.1 1257693 R 552526 CDS YP_002123578.1 195978334 6760402 complement(1258002..1258787) 1 NC_011134.1 similar to ref|NP_607143.1| tributyrin esterase [Streptococcus pyogenes MGAS8232]; acetyl esterase 1258787 6760402 Sez_1225 Streptococcus equi subsp. zooepidemicus MGCS10565 acetyl esterase YP_002123578.1 1258002 R 552526 CDS YP_002123579.1 195978335 6760400 complement(1258893..1260554) 1 NC_011134.1 similar to ref|YP_060090.1| Zn-dependent hydrolase [Streptococcus pyogenes MGAS10394]; metallo-beta-lactamase family protein 1260554 6760400 Sez_1226 Streptococcus equi subsp. zooepidemicus MGCS10565 metallo-beta-lactamase family protein YP_002123579.1 1258893 R 552526 CDS YP_002123580.1 195978336 6760398 complement(1260764..1261522) 1 NC_011134.1 similar to ref|NP_607141.1| ABC transporter (ATP-binding protein) [Streptococcus pyogenes MGAS8232]; Part of the ABC transporter complex. Responsible for energy coupling to the transport system.; ABC transporter ATP-binding protein 1261522 6760398 Sez_1227 Streptococcus equi subsp. zooepidemicus MGCS10565 ABC transporter ATP-binding protein YP_002123580.1 1260764 R 552526 CDS YP_002123581.1 195978337 6760396 complement(1261519..1262010) 1 NC_011134.1 similar to ref|YP_602391.1| ABC transporter permease [Streptococcus pyogenes MGAS10750]; Part Of The Binding-Protein-Dependent Transport System For Ribose. Probably Responsible For The Translocation Of The Substrate Across The Membrane.; ABC transporter permease 1262010 6760396 Sez_1228 Streptococcus equi subsp. zooepidemicus MGCS10565 ABC transporter permease YP_002123581.1 1261519 R 552526 CDS YP_002123582.1 195978338 6760394 complement(1262001..1262387) 1 NC_011134.1 similar to ref|ZP_00788072.1| ABC transporter, permease [Streptococcus agalactiae CJB111]; ABC transporter permease 1262387 6760394 Sez_1229 Streptococcus equi subsp. zooepidemicus MGCS10565 ABC transporter permease YP_002123582.1 1262001 R 552526 CDS YP_002123583.1 195978339 6760391 complement(1262401..1263396) 1 NC_011134.1 similar to ref|YP_329889.1| ABC transporter, substrate-binding protein, [Streptococcus agalactiae A909]; ABC transporter substrate-binding protein 1263396 6760391 Sez_1230 Streptococcus equi subsp. zooepidemicus MGCS10565 ABC transporter substrate-binding protein YP_002123583.1 1262401 R 552526 CDS YP_002123584.1 195978340 6760390 1263502..1263684 1 NC_011134.1 hypothetical protein 1263684 6760390 Sez_1231 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123584.1 1263502 D 552526 CDS YP_002123585.1 195978341 6760388 1263681..1265417 1 NC_011134.1 similar to ref|YP_280188.1| fibrinogen-binding protein [Streptococcus pyogenes MGAS6180]; adhesin, lacks a canonical Sec pathway amino terminal secretion-signal peptide.; fibronectin/fibrinogen-binding protein Fbp-like 1265417 fbp 6760388 fbp Streptococcus equi subsp. zooepidemicus MGCS10565 fibronectin/fibrinogen-binding protein Fbp-like YP_002123585.1 1263681 D 552526 CDS YP_002123586.1 195978342 6760386 complement(1265505..1266743) 1 NC_011134.1 similar to ref|YP_282102.1| tetratricopeptide repeat family protein [Streptococcus pyogenes MGAS5005]; hypothetical protein 1266743 6760386 Sez_1233 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123586.1 1265505 R 552526 CDS YP_002123587.1 195978343 6760384 complement(1266733..1267914) 1 NC_011134.1 similar to ref|YP_602385.1| hypothetical membrane spanning protein [Streptococcus pyogenes MGAS10750]; hypothetical protein 1267914 6760384 Sez_1234 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123587.1 1266733 R 552526 CDS YP_002123588.1 195978344 6761252 complement(1267977..1268453) 1 NC_011134.1 similar to ref|NP_664453.1| dGTP pyrophosphohydrolase [Streptococcus pyogenes MGAS315]; Involved in the DNA repair system to avoid A.T to G.C transversions. Degrades 8-oxo-dGTP to the monophosphate, but is also active on all of the nucleoside triphosphates.; mutator protein MutT 1268453 mutT 6761252 mutT Streptococcus equi subsp. zooepidemicus MGCS10565 mutator protein MutT YP_002123588.1 1267977 R 552526 CDS YP_002123589.1 195978345 6760382 complement(1268631..1269677) 1 NC_011134.1 similar to pdb|1KEP|A Chain A, the crystal structure of dTDP-D-glucose 4,6-dehydratase (RmlB) from Streptococcus suis with dTDP-xylose bound; Catalysis of the reaction: dTDP-glucose = dTDP-4-dehydro-6-deoxy-D-glucose + H2O.; dTDP-glucose 4,6-dehydratase RmlB 1269677 rmlB 6760382 rmlB Streptococcus equi subsp. zooepidemicus MGCS10565 dTDP-glucose 4,6-dehydratase RmlB YP_002123589.1 1268631 R 552526 CDS YP_002123590.1 195978346 6760379 complement(1269924..1270466) 1 NC_011134.1 similar to ref|NP_688208.1| dTDP-4-dehydrorhamnose 3,5-epimerase [Streptococcus agalactiae 2603V/R]; Catalysis of the reaction: dTDP-4-dehydro-6-deoxy-D-glucose = dTDP-4-dehydro-6-deoxy-L-mannose.; dTDP-4-Keto-6-Deoxyglucose-3 5-epimerase RmlC 1270466 rmlC 6760379 rmlC Streptococcus equi subsp. zooepidemicus MGCS10565 dTDP-4-Keto-6-Deoxyglucose-3 5-epimerase RmlC YP_002123590.1 1269924 R 552526 CDS YP_002123591.1 195978347 6760376 complement(1270466..1271335) 1 NC_011134.1 similar to ref|YP_280182.1| glucose-1-phosphate thymidylyltransferase [Streptococcus pyogenes MGAS6180]; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.; glucose-1-phosphate thymidylyltransferase 1271335 rmlA 6760376 rmlA Streptococcus equi subsp. zooepidemicus MGCS10565 glucose-1-phosphate thymidylyltransferase YP_002123591.1 1270466 R 552526 CDS YP_002123592.1 195978348 6760374 complement(1271392..1272537) 1 NC_011134.1 similar to ref|YP_596523.1| glycine/D-amino acid oxidases family [Streptococcus pyogenes MGAS9429]; glycine/D-amino acid oxidases family 1272537 6760374 Sez_1239 Streptococcus equi subsp. zooepidemicus MGCS10565 glycine/D-amino acid oxidases family YP_002123592.1 1271392 R 552526 CDS YP_002123593.1 195978349 6761006 complement(1272556..1273344) 1 NC_011134.1 similar to ref|YP_001128625.1| NIF3 (NGG1p interacting factor 3) family protein [Streptococcus pyogenes str. Manfredo]; hypothetical protein 1273344 6761006 Sez_1240 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123593.1 1272556 R 552526 CDS YP_002123594.1 195978350 6760373 complement(1273334..1274020) 1 NC_011134.1 similar to ref|NP_269124.1| hypothetical protein SPy_0930 [Streptococcus pyogenes M1 GAS]; tRNA-m1A22 methylase 1274020 6760373 Sez_1241 Streptococcus equi subsp. zooepidemicus MGCS10565 tRNA-m1A22 methylase YP_002123594.1 1273334 R 552526 CDS YP_002123595.1 195978351 6760371 complement(1274094..1274756) 1 NC_011134.1 similar to ref|YP_598398.1| Endonuclease III [Streptococcus pyogenes MGAS10270]; Has both an apurinic and/or apyrimidinic endonuclease activity and a DNA N-glycosylase activity. Incises damaged DNA at cytosines, thymines and guanines. Acts on a damaged strand, 5' from the damaged site. Required for the repair of both oxidative DNA damage and spontaneous mutagenic lesions.; endonuclease III 1274756 6760371 Sez_1242 Streptococcus equi subsp. zooepidemicus MGCS10565 endonuclease III YP_002123595.1 1274094 R 552526 CDS YP_002123596.1 195978352 6760369 complement(1274756..1275496) 1 NC_011134.1 similar to ref|YP_598397.1| DNA replication protein dnaD [Streptococcus pyogenes MGAS10270]; component of primosome involved in the initiation of DNA replication.; DNA replication protein DnaD 1275496 dnaD 6760369 dnaD Streptococcus equi subsp. zooepidemicus MGCS10565 DNA replication protein DnaD YP_002123596.1 1274756 R 552526 CDS YP_002123597.1 195978353 6761257 complement(1275500..1276018) 1 NC_011134.1 catalyzes a salvage reaction resulting in the formation of AMP which is metabolically less costly than a de novo synthesis; adenine phosphoribosyltransferase 1276018 apt 6761257 apt Streptococcus equi subsp. zooepidemicus MGCS10565 adenine phosphoribosyltransferase YP_002123597.1 1275500 R 552526 CDS YP_002123598.1 195978354 6760367 complement(1276098..1276466) 1 NC_011134.1 similar to ref|YP_001035269.1| hypothetical protein SSA_1320 [Streptococcus sanguinis SK36]; hypothetical protein 1276466 6760367 Sez_1245 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123598.1 1276098 R 552526 CDS YP_002123599.1 195978355 6760986 complement(1276475..1278685) 1 NC_011134.1 similar to ref|YP_598395.1| Single-stranded-DNA-specific exonuclease recJ [Streptococcus pyogenes MGAS10270]; Single-stranded-DNA-specific exonuclease. Required for many types of recombinational events, although the stringency of the requirement for recJ appears to vary with the type of recombinational event monitored and the other recombination gene products which are available.; single-stranded-DNA-specific exonuclease RecJ 1278685 recJ 6760986 recJ Streptococcus equi subsp. zooepidemicus MGCS10565 single-stranded-DNA-specific exonuclease RecJ YP_002123599.1 1276475 R 552526 CDS YP_002123600.1 195978356 6761134 complement(1278682..1279446) 1 NC_011134.1 similar to ref|NP_664442.1| oxidoreductase, short chain dehydrogenase/reductase family [Streptococcus pyogenes MGAS315]; short chain dehydrogenase 1279446 6761134 Sez_1247 Streptococcus equi subsp. zooepidemicus MGCS10565 short chain dehydrogenase YP_002123600.1 1278682 R 552526 CDS YP_002123601.1 195978357 6761262 complement(1279446..1280375) 1 NC_011134.1 member of metallo-beta-lactamase family; the purified enzyme from Escherichia coli forms dimeric zinc phosphodiesterase; in Bacillus subtilis this protein is a 3'-tRNA processing endoribonuclease and is essential while in Escherichia coli it is not; associates with two zinc ions; ribonuclease Z 1280375 rnz 6761262 rnz Streptococcus equi subsp. zooepidemicus MGCS10565 ribonuclease Z YP_002123601.1 1279446 R 552526 CDS YP_002123602.1 195978358 6760366 complement(1280390..1281025) 1 NC_011134.1 similar to ref|YP_280172.1| cystathionine beta-lyase [Streptococcus pyogenes MGAS6180]; hypothetical protein 1281025 6760366 Sez_1249 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123602.1 1280390 R 552526 CDS YP_002123603.1 195978359 6761095 complement(1281018..1282256) 1 NC_011134.1 similar to ref|NP_607120.1| GTP-binding protein [Streptococcus pyogenes MGAS8232]; GTP-binding protein HflX 1282256 hflX 6761095 hflX Streptococcus equi subsp. zooepidemicus MGCS10565 GTP-binding protein HflX YP_002123603.1 1281018 R 552526 CDS YP_002123604.1 195978360 6761197 complement(1282341..1283231) 1 NC_011134.1 IPP transferase; isopentenyltransferase; involved in tRNA modification; in Escherichia coli this enzyme catalyzes the addition of a delta2-isopentenyl group from dimethylallyl diphosphate to the N6-nitrogen of adenosine adjacent to the anticodon of tRNA species that read codons starting with uracil; further tRNA modifications may occur; mutations in miaA result in defects in translation efficiency and fidelity; tRNA delta(2)-isopentenylpyrophosphate transferase 1283231 miaA 6761197 miaA Streptococcus equi subsp. zooepidemicus MGCS10565 tRNA delta(2)-isopentenylpyrophosphate transferase YP_002123604.1 1282341 R 552526 CDS YP_002123605.1 195978361 6761322 1283358..1283540 1 NC_011134.1 similar to ref|YP_602309.1| hypothetical protein MGAS10750_Spy0815 [Streptococcus pyogenes MGAS10750]; hypothetical protein 1283540 6761322 Sez_1252 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123605.1 1283358 D 552526 CDS YP_002123606.1 195978362 6761030 complement(1283696..1284343) 1 NC_011134.1 similar to ref|YP_895632.1| possible uridine kinase [Bacillus thuringiensis str. Al Hakam]; hypothetical protein 1284343 6761030 Sez_1253 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123606.1 1283696 R 552526 CDS YP_002123607.1 195978363 6761164 complement(1284510..1286774) 1 NC_011134.1 similar to ref|YP_280504.1| glycogen phosphorylase [Streptococcus pyogenes MGAS6180]; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.; maltodextrin phosphorylase 1286774 malP 6761164 malP Streptococcus equi subsp. zooepidemicus MGCS10565 maltodextrin phosphorylase YP_002123607.1 1284510 R 552526 CDS YP_002123608.1 195978364 6761024 complement(1286800..1288275) 1 NC_011134.1 amylomaltase; acts to release glucose from maltodextrins; 4-alpha-glucanotransferase 1288275 malQ 6761024 malQ Streptococcus equi subsp. zooepidemicus MGCS10565 4-alpha-glucanotransferase YP_002123608.1 1286800 R 552526 CDS YP_002123609.1 195978365 6760998 complement(1288507..1289529) 1 NC_011134.1 similar to ref|YP_596834.1| transcriptional regulator, LacI family [Streptococcus pyogenes MGAS9429]; Transcriptional repressor of the malA gene for maltase.; maltose operon transcriptional repressor MalR 1289529 malR 6760998 malR Streptococcus equi subsp. zooepidemicus MGCS10565 maltose operon transcriptional repressor MalR YP_002123609.1 1288507 R 552526 CDS YP_002123610.1 195978366 6761297 1289778..1291031 1 NC_011134.1 similar to ref|YP_596835.1| maltose/maltodextrin-binding protein [Streptococcus pyogenes MGAS9429]; Binding protein for maltose and maltodextrin; involved in its cellular uptake.; maltose/maltodextrin ABC transporter substrate binding periplasmic protein MalE 1291031 malE 6761297 malE Streptococcus equi subsp. zooepidemicus MGCS10565 maltose/maltodextrin ABC transporter substrate binding periplasmic protein MalE YP_002123610.1 1289778 D 552526 CDS YP_002123611.1 195978367 6761186 1291331..1292692 1 NC_011134.1 similar to ref|NP_269422.1| maltose/maltodextrin ABC transport system (permease) [Streptococcus pyogenes M1 GAS]; Part of the binding-protein-dependent transport system for maltodextrin; probably responsible for the translocation of the substrate across the membrane.; maltodextrin ABC transporter permease 1292692 malF 6761186 malF Streptococcus equi subsp. zooepidemicus MGCS10565 maltodextrin ABC transporter permease YP_002123611.1 1291331 D 552526 CDS YP_002123612.1 195978368 6761067 1292692..1293528 1 NC_011134.1 similar to ref|NP_269423.1| maltose/maltodextrin ABC transport system (permease) [Streptococcus pyogenes M1 GAS]; Part of the binding-protein-dependent transport system for maltodextrin; probably responsible for the translocation of the substrate across the membrane.; maltose ABC transporter permease 1293528 malG 6761067 malG Streptococcus equi subsp. zooepidemicus MGCS10565 maltose ABC transporter permease YP_002123612.1 1292692 D 552526 CDS YP_002123613.1 195978369 6761306 complement(1293602..1294432) 1 NC_011134.1 similar to ref|YP_598727.1| Maltodextrose utilization protein malA [Streptococcus pyogenes MGAS10270]; Has a role in maltotetraose utilization.; maltodextrose utilization protein MalA 1294432 malA 6761306 malA Streptococcus equi subsp. zooepidemicus MGCS10565 maltodextrose utilization protein MalA YP_002123613.1 1293602 R 552526 CDS YP_002123614.1 195978370 6760360 complement(1295315..1296619) 1 NC_011134.1 similar to ref|NP_269427.1| maltodextrin transport system permease [Streptococcus pyogenes M1 GAS]; Part of the binding-protein-dependent transport system for maltodextrin; probably responsible for the translocation of the substrate across the membrane.; maltodextrin ABC transporter permease 1296619 malC 6760360 malC Streptococcus equi subsp. zooepidemicus MGCS10565 maltodextrin ABC transporter permease YP_002123614.1 1295315 R 552526 CDS YP_002123615.1 195978371 6760358 complement(1296695..1298854) 1 NC_011134.1 similar to ref|YP_280514.1| alpha-amylase [Streptococcus pyogenes MGAS6180]; Degrades starch to alpha-, beta-, and gamma- cyclodextrins, as well as linear sugars.; cyclomaltodextrin glucanotransferase 1298854 amyA 6760358 amyA Streptococcus equi subsp. zooepidemicus MGCS10565 cyclomaltodextrin glucanotransferase YP_002123615.1 1296695 R 552526 CDS YP_002123616.1 195978372 6760355 complement(1298856..1300556) 1 NC_011134.1 similar to ref|YP_598731.1| Neopullulanase / Cyclomaltodextrinase / Maltogenic alpha-amylase [Streptococcus pyogenes MGAS10270]; Hydrolyzes cyclodextrins. Can also act on linear maltodextrins, with the exception of maltose.; cyclomaltodextrinase 1300556 amyB 6760355 amyB Streptococcus equi subsp. zooepidemicus MGCS10565 cyclomaltodextrinase YP_002123616.1 1298856 R 552526 CDS YP_002123617.1 195978373 6760353 complement(1300729..1301988) 1 NC_011134.1 similar to ref|YP_280516.1| maltose/maltodextrin-binding protein [Streptococcus pyogenes MGAS6180]; Binding protein for maltose and maltodextrin; involved in its cellular uptake.; maltose/maltodextrin-binding lipoprotein precursor MalX 1301988 malX 6760353 malX Streptococcus equi subsp. zooepidemicus MGCS10565 maltose/maltodextrin-binding lipoprotein precursor MalX YP_002123617.1 1300729 R 552526 CDS YP_002123618.1 195978374 6760825 complement(1302529..1303497) 1 NC_011134.1 similar to ref|NP_269431.1| esterase [Streptococcus pyogenes M1 GAS]; This protein removes the N-acetyl group from bialaphos as one of the final steps of the bialaphos biosynthetic pathway.; esterase 1303497 6760825 Sez_1267 Streptococcus equi subsp. zooepidemicus MGCS10565 esterase YP_002123618.1 1302529 R 552526 CDS YP_002123619.1 195978375 6760808 complement(1303537..1304790) 1 NC_011134.1 similar to ref|NP_664795.1| hypothetical protein DltD [Streptococcus pyogenes MGAS315]; Could be responsible for the transfer of D-alanine residues from D-Ala-undecaprenol phosphate to the poly(glycerophosphate) chains.; poly(glycerophosphate chain) D-alanine transfer protein DltD 1304790 dltD 6760808 dltD Streptococcus equi subsp. zooepidemicus MGCS10565 poly(glycerophosphate chain) D-alanine transfer protein DltD YP_002123619.1 1303537 R 552526 CDS YP_002123620.1 195978376 6760572 complement(1304783..1305022) 1 NC_011134.1 D-alanyl carrier protein subunit; involved in the incorporation of D-alanine into membrane-associated D-alanyl-lipoteichoic acid; D-alanyl carrier protein is the acceptor of activated D-alanine which it donates to a membrane acceptor(D-alanyl transferase) for incorporation into membrane lipoteichoic acid; D-alanine--poly(phosphoribitol) ligase subunit 2 1305022 dltC 6760572 dltC Streptococcus equi subsp. zooepidemicus MGCS10565 D-alanine--poly(phosphoribitol) ligase subunit 2 YP_002123620.1 1304783 R 552526 CDS YP_002123621.1 195978377 6760835 complement(1305040..1306299) 1 NC_011134.1 similar to ref|YP_060360.1| DltB [Streptococcus pyogenes MGAS10394]; Could be involved in the transport of activated D- alanine through the membrane.; D-alanyl transfer protein DltB 1306299 dltB 6760835 dltB Streptococcus equi subsp. zooepidemicus MGCS10565 D-alanyl transfer protein DltB YP_002123621.1 1305040 R 552526 CDS YP_002123622.1 195978378 6760963 complement(1306296..1307834) 1 NC_011134.1 transfers D-alanine to the D-alanyl carrier protein during the incorporation of D-alanine into lipoteichoic acid; D-alanine--poly(phosphoribitol) ligase subunit 1 1307834 dltA 6760963 dltA Streptococcus equi subsp. zooepidemicus MGCS10565 D-alanine--poly(phosphoribitol) ligase subunit 1 YP_002123622.1 1306296 R 552526 CDS YP_002123623.1 195978379 6762346 complement(1307846..1307989) 1 NC_011134.1 similar to ref|NP_607430.1| hypothetical protein spyM18_1325 [Streptococcus pyogenes MGAS8232]; hypothetical protein 1307989 6762346 Sez_1272 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123623.1 1307846 R 552526 CDS YP_002123624.1 195978380 6760735 complement(1308328..1310319) 1 NC_011134.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion; excinuclease ABC subunit B 1310319 uvrB 6760735 uvrB Streptococcus equi subsp. zooepidemicus MGCS10565 excinuclease ABC subunit B YP_002123624.1 1308328 R 552526 CDS YP_002123625.1 195978381 6762353 1310535..1312676 1 NC_011134.1 similar to ref|YP_001128349.1| glutamine ABC transporter,glutamine-binding protein/permease [Streptococcus pyogenes str. Manfredo]; Part of the binding-protein-dependent transport system for glutamine; probably responsible for the translocation of the substrate across the membrane.; glutamine ABC transporter, glutamine-binding protein/permease GlnP 1312676 glnP 6762353 glnP Streptococcus equi subsp. zooepidemicus MGCS10565 glutamine ABC transporter, glutamine-binding protein/permease GlnP YP_002123625.1 1310535 D 552526 CDS YP_002123626.1 195978382 6762328 1312676..1313416 1 NC_011134.1 similar to ref|YP_280526.1| glutamine transport ATP-binding protein [Streptococcus pyogenes MGAS6180]; Probably part of a binding-protein-dependent transport system for an amino acid. Probably responsible for energy coupling to the transport system.; glutamine transport ATP-binding protein GlnQ 1313416 glnQ 6762328 glnQ Streptococcus equi subsp. zooepidemicus MGCS10565 glutamine transport ATP-binding protein GlnQ YP_002123626.1 1312676 D 552526 CDS YP_002123627.1 195978383 6762325 complement(1313405..1313569) 1 NC_011134.1 hypothetical protein 1313569 6762325 Sez_1276 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123627.1 1313405 R 552526 CDS YP_002123628.1 195978384 6762345 complement(1313573..1313725) 1 NC_011134.1 similar to ref|NP_607434.1| hypothetical protein spyM18_1329 [Streptococcus pyogenes MGAS8232]; hypothetical protein 1313725 6762345 Sez_1277 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123628.1 1313573 R 552526 CDS YP_002123629.1 195978385 6762337 complement(1313722..1315101) 1 NC_011134.1 similar to ref|YP_282442.1| PTS system, cellobiose-specific IIC component [Streptococcus pyogenes MGAS5005]; The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. This system is involved in cellobiose transport.; cellobiose permease IIC component CelB 1315101 celB 6762337 celB Streptococcus equi subsp. zooepidemicus MGCS10565 cellobiose permease IIC component CelB YP_002123629.1 1313722 R 552526 CDS YP_002123630.1 195978386 6762334 complement(1315176..1315613) 1 NC_011134.1 similar to ref|YP_060367.1| hypothetical protein M6_Spy1049 [Streptococcus pyogenes MGAS10394]; hypothetical protein 1315613 6762334 Sez_1279 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123630.1 1315176 R 552526 CDS YP_002123631.1 195978387 6762309 complement(1315610..1315945) 1 NC_011134.1 similar to ref|NP_269440.1| PTS enzyme III [Streptococcus pyogenes M1 GAS]; The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. This system is involved in lichenan transport.; cellobiose-specific phosphotransferase enzyme IIA component 1315945 celA 6762309 celA Streptococcus equi subsp. zooepidemicus MGCS10565 cellobiose-specific phosphotransferase enzyme IIA component YP_002123631.1 1315610 R 552526 CDS YP_002123632.1 195978388 6762319 complement(1315942..1316259) 1 NC_011134.1 similar to ref|YP_001128343.1| lactose/cellobiose-specific phosphotransferase system (PTS), IIB component [Streptococcus pyogenes str. Manfredo]; The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active-transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. This system is involved in cellobiose transport.; cellobiose-specific phosphotransferase enzyme IIB component 1316259 6762319 Sez_1281 Streptococcus equi subsp. zooepidemicus MGCS10565 cellobiose-specific phosphotransferase enzyme IIB component YP_002123632.1 1315942 R 552526 CDS YP_002123633.1 195978389 6762294 complement(1316273..1318270) 1 NC_011134.1 similar to gb|AAX72177.1| transcription antiterminator, BglG family [Streptococcus pyogenes MGAS6180]; Positive regulator of the licABCH operon.; BglG family transcription antiterminator/PTS system transporter subunit IIA 1318270 6762294 Sez_1282 Streptococcus equi subsp. zooepidemicus MGCS10565 BglG family transcription antiterminator/PTS system transporter subunit IIA YP_002123633.1 1316273 R 552526 CDS YP_002123634.1 195978390 6762312 complement(1318373..1319470) 1 NC_011134.1 similar to ref|YP_060371.1| outer surface protein [Streptococcus pyogenes MGAS10394]; outer membrane protein 1319470 6762312 Sez_1283 Streptococcus equi subsp. zooepidemicus MGCS10565 outer membrane protein YP_002123634.1 1318373 R 552526 CDS YP_002123635.1 195978391 6762303 1321204..1321920 1 NC_011134.1 similar to ref|YP_001128339.1| nicotinamide mononucleotide transporter [Streptococcus pyogenes str. Manfredo]; ribosyl nicotinamide transporter PnuC-like 1321920 pnuC 6762303 pnuC Streptococcus equi subsp. zooepidemicus MGCS10565 ribosyl nicotinamide transporter PnuC-like YP_002123635.1 1321204 D 552526 CDS YP_002123636.1 195978392 6762299 complement(1321973..1322131) 1 NC_011134.1 similar to ref|NP_269446.1| hypothetical protein SPy_1332 [Streptococcus pyogenes M1 GAS]; hypothetical protein 1322131 6762299 Sez_1287 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123636.1 1321973 R 552526 CDS YP_002123637.1 195978393 6762296 complement(1322246..1323553) 1 NC_011134.1 essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication; GTPase ObgE 1323553 obgE 6762296 obgE Streptococcus equi subsp. zooepidemicus MGCS10565 GTPase ObgE YP_002123637.1 1322246 R 552526 CDS YP_002123638.1 195978394 6762286 1324001..1325296 1 NC_011134.1 similar to ref|ZP_00790289.1| aminopeptidase PepS [Streptococcus agalactiae 515]; Exhibits a high specificity towards peptides possessing arginine or aromatic amino acids at the N-terminus. Could be involved both in bacterial growth by supplying amino acids.; aminopeptidase 1325296 pepS 6762286 pepS Streptococcus equi subsp. zooepidemicus MGCS10565 aminopeptidase YP_002123638.1 1324001 D 552526 CDS YP_002123639.1 195978395 6762289 complement(1325320..1326033) 1 NC_011134.1 similar to ref|YP_001201503.1| 16S rRNA uridine-516 pseudouridylate synthase and related Pseudouridylate synthase [Streptococcus suis 98HAH33]; Responsible for synthesis of pseudouridine from uracil- 516 in 16S ribosomal RNA.; ribosomal small subunit pseudouridine synthase A RsuA 1326033 rsuA 6762289 rsuA Streptococcus equi subsp. zooepidemicus MGCS10565 ribosomal small subunit pseudouridine synthase A RsuA YP_002123639.1 1325320 R 552526 CDS YP_002123640.1 195978396 6762284 1326198..1326557 1 NC_011134.1 similar to ref|NP_269451.1| hypothetical protein SPy_1339 [Streptococcus pyogenes M1 GAS]; dihydrolipoamide acyltransferase 1326557 6762284 Sez_1291 Streptococcus equi subsp. zooepidemicus MGCS10565 dihydrolipoamide acyltransferase YP_002123640.1 1326198 D 552526 CDS YP_002123641.1 195978397 6762265 complement(1326648..1327871) 1 NC_011134.1 similar to ref|YP_001128328.1| major facilitator superfamily protein [Streptococcus pyogenes str. Manfredo]; major facilitator family transporter 1327871 6762265 Sez_1292 Streptococcus equi subsp. zooepidemicus MGCS10565 major facilitator family transporter YP_002123641.1 1326648 R 552526 CDS YP_002123642.1 195978398 6762277 1328231..1329715 1 NC_011134.1 similar to ref|NP_664825.1| ATP-dependent Zn protease [Streptococcus pyogenes MGAS315]; hypothetical protein 1329715 6762277 Sez_1293 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123642.1 1328231 D 552526 CDS YP_002123643.1 195978399 6762271 complement(1329771..1330175) 1 NC_011134.1 similar to ref|YP_596870.1| thioesterase superfamily protein [Streptococcus pyogenes MGAS9429]; Phenylacetic acid aerobic catabolism.; phenylacetic acid degradation protein PaaI 1330175 paaI 6762271 paaI Streptococcus equi subsp. zooepidemicus MGCS10565 phenylacetic acid degradation protein PaaI YP_002123643.1 1329771 R 552526 CDS YP_002123644.1 195978400 6762268 complement(1330703..1330861) 1 NC_011134.1 hypothetical protein 1330861 6762268 Sez_1295 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123644.1 1330703 R 552526 CDS YP_002123645.1 195978401 6762263 complement(1331086..1331622) 1 NC_011134.1 similar to ref|YP_319963.1| hypothetical protein Ava_B0060 [Anabaena variabilis ATCC 29413]; GNAT family acetyltransferase 1331622 6762263 Sez_1296 Streptococcus equi subsp. zooepidemicus MGCS10565 GNAT family acetyltransferase YP_002123645.1 1331086 R 552526 CDS YP_002123646.1 195978402 6762260 complement(1331818..1332456) 1 NC_011134.1 similar to ref|NP_664256.1| hypothetical protein SpyM3_0452 [Streptococcus pyogenes MGAS315]; Displays high phosphatase activity toward erythrose 4- phosphate, fructose 6-phosphate, 2-deoxyglucose 6-phosphate, and mannose 6-phosphate. May have a role in the intracellular metabolism of many phosphorylated carbohydrates.; phosphorylated carbohydrates phosphatase 1332456 6762260 Sez_1297 Streptococcus equi subsp. zooepidemicus MGCS10565 phosphorylated carbohydrates phosphatase YP_002123646.1 1331818 R 552526 CDS YP_002123647.1 195978403 6762258 1332644..1333045 1 NC_011134.1 similar to emb|CAG09263.1| unnamed protein product [Tetraodon nigroviridis]; hypothetical protein 1333045 6762258 Sez_1298 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123647.1 1332644 D 552526 CDS YP_002123648.1 195978404 6762255 complement(1333221..1336412) 1 NC_011134.1 similar to gb|ABV69920.1| hyaluronidase [Streptococcus equi subsp. zooepidemicus]; hyaluronate lyase precursor HylB 1336412 hylB 6762255 hylB Streptococcus equi subsp. zooepidemicus MGCS10565 hyaluronate lyase precursor HylB YP_002123648.1 1333221 R 552526 CDS YP_002123649.1 195978405 6762251 complement(1336452..1337081) 1 NC_011134.1 catalyzes the formation of pyruvate and glyoxylate from 4-hydroxy-2-oxoglutarate; or pyruvate and D-glyceraldehyde 3-phosphate from 2-dehydro-3-deoxy-D-glyconate 6-phosphate; keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase 1337081 kdgA 6762251 kdgA Streptococcus equi subsp. zooepidemicus MGCS10565 keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase YP_002123649.1 1336452 R 552526 CDS YP_002123650.1 195978406 6762245 complement(1337083..1338084) 1 NC_011134.1 similar to ref|YP_602039.1| 2-dehydro-3-deoxygluconokinase [Streptococcus pyogenes MGAS10750]; Catalysis of the reaction: ATP + 2-dehydro-3-deoxy-D-gluconate = ADP + beta-L-arabinose 1-phosphate.; 2-dehydro-3-deoxygluconokinase 1338084 kdgK 6762245 kdgK Streptococcus equi subsp. zooepidemicus MGCS10565 2-dehydro-3-deoxygluconokinase YP_002123650.1 1337083 R 552526 CDS YP_002123651.1 195978407 6762226 complement(1338117..1338758) 1 NC_011134.1 similar to gb|ABF33585.1| Galactose-6-phosphate isomerase LacB subunit [Streptococcus pyogenes MGAS10270]; hypothetical protein 1338758 6762226 Sez_1302 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123651.1 1338117 R 552526 CDS YP_002123652.1 195978408 6762240 complement(1338785..1339582) 1 NC_011134.1 Involved in the nonphosphorylative, ketogenic oxidation of glucose and oxidizes gluconate to 5-ketogluconate; gluconate 5-dehydrogenase 1339582 6762240 Sez_1303 Streptococcus equi subsp. zooepidemicus MGCS10565 gluconate 5-dehydrogenase YP_002123652.1 1338785 R 552526 CDS YP_002123653.1 195978409 6762238 1339889..1340323 1 NC_011134.1 similar to ref|YP_059862.1| PTS system, N-acetylgalactosamine-specific IIA component [Streptococcus pyogenes MGAS10394]; Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + sugar(out) = protein histidine + sugar phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport.; PTS system N-acetylgalactosamine- and galactosamine-specific transporter subunit IIA AgaA 1340323 agaA 6762238 agaA Streptococcus equi subsp. zooepidemicus MGCS10565 PTS system N-acetylgalactosamine- and galactosamine-specific transporter subunit IIA AgaA YP_002123653.1 1339889 D 552526 CDS YP_002123654.1 195978410 6762236 1340323..1341522 1 NC_011134.1 similar to ref|YP_596245.1| unsaturated glucuronyl hydrolase [Streptococcus pyogenes MGAS9429]; Catalyzes the hydrolysis of oligosaccharides with unsaturated glucuronyl residues at the nonreducing terminal, to a sugar or an amino sugar, and an unsaturated D-glucuronic acid (GlcA), which is nonenzymatically converted immediately to alpha- keto acid.; unsaturated glucuronyl hydrolase 1341522 6762236 Sez_1305 Streptococcus equi subsp. zooepidemicus MGCS10565 unsaturated glucuronyl hydrolase YP_002123654.1 1340323 D 552526 CDS YP_002123655.1 195978411 6762234 1341568..1342056 1 NC_011134.1 similar to ref|YP_279969.1| PTS system, N-acetylgalactosamine-specific IIB component [Streptococcus pyogenes MGAS6180]; The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. This system is involved in N-acetylgalactosamine transport.; N-acetylgalactosamine-specific phosphotransferase enzyme IIB component AgaB 1342056 agaB 6762234 agaB Streptococcus equi subsp. zooepidemicus MGCS10565 N-acetylgalactosamine-specific phosphotransferase enzyme IIB component AgaB YP_002123655.1 1341568 D 552526 CDS YP_002123656.1 195978412 6762224 1342134..1342850 1 NC_011134.1 similar to ref|NP_268877.1| PTS dependent N-acetyl-galactosamine-IIC component [Streptococcus pyogenes M1 GAS]; The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. This system is involved in N-acetylgalactosamine transport.; N-acetylgalactosamine permease IIC component AgaC 1342850 agaC 6762224 agaC Streptococcus equi subsp. zooepidemicus MGCS10565 N-acetylgalactosamine permease IIC component AgaC YP_002123656.1 1342134 D 552526 CDS YP_002123657.1 195978413 6762218 1342804..1343658 1 NC_011134.1 similar to ref|YP_059858.1| PTS system, N-acetylgalactosamine-specific IID component [Streptococcus pyogenes MGAS10394]; The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. This system is involved in N-acetylgalactosamine transport.; N-acetylgalactosamine permease IID component AgaD 1343658 agaD 6762218 agaD Streptococcus equi subsp. zooepidemicus MGCS10565 N-acetylgalactosamine permease IID component AgaD YP_002123657.1 1342804 D 552526 CDS YP_002123658.1 195978414 6762195 1344058..1345059 1 NC_011134.1 similar to ref|YP_602030.1| Transcriptional regulator, LacI family [Streptococcus pyogenes MGAS10750]; Sugar-binding transcriptional regulator.; LacI family transcriptional regulator 1345059 6762195 Sez_1309 Streptococcus equi subsp. zooepidemicus MGCS10565 LacI family transcriptional regulator YP_002123658.1 1344058 D 552526 CDS YP_002123659.1 195978415 6762188 1345635..1345916 1 NC_011134.1 similar to ref|YP_001451052.1| hypothetical protein SGO_1783 [Streptococcus gordonii str. Challis substr. CH1]; hypothetical protein 1345916 6762188 Sez_1310 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123659.1 1345635 D 552526 CDS YP_002123660.1 195978416 6762212 1345913..1346272 1 NC_011134.1 similar to ref|YP_001035341.1| hypothetical protein SSA_1393 [Streptococcus sanguinis SK36]; hypothetical protein 1346272 6762212 Sez_1311 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123660.1 1345913 D 552526 CDS YP_002123661.1 195978417 6762206 1346263..1347669 1 NC_011134.1 similar to ref|YP_001035340.1| hypothetical protein SSA_1392 [Streptococcus sanguinis SK36]; hypothetical protein 1347669 6762206 Sez_1312 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123661.1 1346263 D 552526 CDS YP_002123662.1 195978418 6762204 1347693..1348172 1 NC_011134.1 similar to ref|YP_001035338.1| hypothetical protein SSA_1390 [Streptococcus sanguinis SK36]; hypothetical protein 1348172 6762204 Sez_1313 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123662.1 1347693 D 552526 CDS YP_002123663.1 195978419 6762153 complement(1348371..1351052) 1 NC_011134.1 similar to ref|NP_664244.1| calcium transporter [Streptococcus pyogenes MGAS315]; Could possibly be a calcium ATPase; cation-transporting ATPase 1351052 6762153 Sez_1314 Streptococcus equi subsp. zooepidemicus MGCS10565 cation-transporting ATPase YP_002123663.1 1348371 R 552526 CDS YP_002123664.1 195978420 6762197 complement(1351402..1351788) 1 NC_011134.1 similar to ref|YP_602028.1| hypothetical cytosolic protein [Streptococcus pyogenes MGAS10750]; hypothetical protein 1351788 6762197 Sez_1315 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123664.1 1351402 R 552526 CDS YP_002123665.1 195978421 6762171 1351869..1353170 1 NC_011134.1 similar to ref|YP_596237.1| dGTP triphosphohydrolase [Streptococcus pyogenes MGAS9429]; Catalysis of the reaction: dGTP + H2O = deoxyguanosine + triphosphate.; deoxyguanosinetriphosphate triphosphohydrolase 1353170 6762171 Sez_1316 Streptococcus equi subsp. zooepidemicus MGCS10565 deoxyguanosinetriphosphate triphosphohydrolase YP_002123665.1 1351869 D 552526 CDS YP_002123666.1 195978422 6762158 complement(1353167..1353358) 1 NC_011134.1 hypothetical protein 1353358 6762158 Sez_1317 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123666.1 1353167 R 552526 CDS YP_002123667.1 195978423 6762172 1353382..1354191 1 NC_011134.1 similar to ref|ZP_00366263.1| COG0561: Predicted hydrolases of the HAD superfamily [Streptococcus pyogenes M49 591]; hydrolase HAD family 1354191 6762172 Sez_1318 Streptococcus equi subsp. zooepidemicus MGCS10565 hydrolase HAD family YP_002123667.1 1353382 D 552526 CDS YP_002123668.1 195978424 6762169 1354191..1355405 1 NC_011134.1 similar to ref|YP_598114.1| UDP-N-acetylmuramoylpentapeptide-lysine N(6)-alanyltransferase / UDP-N-acetylmuramoylpentapeptide-lysine N(6)-seryltransferase [Streptococcus pyogenes MGAS10270]; peptidoglycan branched peptide synthesis protein, serine/alanine adding enzyme MurM 1355405 murM 6762169 murM Streptococcus equi subsp. zooepidemicus MGCS10565 peptidoglycan branched peptide synthesis protein, serine/alanine adding enzyme MurM YP_002123668.1 1354191 D 552526 CDS YP_002123669.1 195978425 6762151 1355405..1356640 1 NC_011134.1 similar to ref|YP_820103.1| Peptidoglycan interpeptide bridge formation enzyme [Streptococcus thermophilus LMD-9]; MurN protein 1356640 murN 6762151 murN Streptococcus equi subsp. zooepidemicus MGCS10565 MurN protein YP_002123669.1 1355405 D 552526 CDS YP_002123670.1 195978426 6762150 complement(1356953..1357711) 1 NC_011134.1 Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate; triosephosphate isomerase 1357711 tpiA 6762150 tpiA Streptococcus equi subsp. zooepidemicus MGCS10565 triosephosphate isomerase YP_002123670.1 1356953 R 552526 CDS YP_002123671.1 195978427 6762143 complement(1357977..1359173) 1 NC_011134.1 EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu; elongation factor Tu 1359173 tuf 6762143 tuf Streptococcus equi subsp. zooepidemicus MGCS10565 elongation factor Tu YP_002123671.1 1357977 R 552526 CDS YP_002123672.1 195978428 6762133 1360122..1363268 1 NC_011134.1 similar to gb|AAN18292.1| immunoreactive protein Se117 [Streptococcus equi]; Unknown, may be a viral enhancing factor (an enhancin); 1st 700aa are virtually identical to immunoreactive protein Se117 of S. equi, and the last 300aa are similar to a chitin-binding protein of B. thuringiensis.; hypothetical protein 1363268 6762133 Sez_1323 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123672.1 1360122 D 552526 CDS YP_002123673.1 195978429 6762132 complement(1363558..1364646) 1 NC_011134.1 similar to ref|ZP_00786125.1| conserved hypothetical protein [Streptococcus agalactiae COH1]; hypothetical protein 1364646 6762132 Sez_1324 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123673.1 1363558 R 552526 CDS YP_002123674.1 195978430 6762107 complement(1364630..1365100) 1 NC_011134.1 similar to gb|AAN18293.1| Se18.7 [Streptococcus equi]; DNA-directed RNA polymerase specialized sigma subunit; RNA polymerase ECF-type sigma factor 1365100 6762107 Sez_1325 Streptococcus equi subsp. zooepidemicus MGCS10565 RNA polymerase ECF-type sigma factor YP_002123674.1 1364630 R 552526 CDS YP_002123675.1 195978431 6762103 1365457..1365666 1 NC_011134.1 similar to ref|YP_001039946.1| hypothetical protein phi3396_59 [Streptococcus phage phi3396]; Possibly involved in regulation has an HTH DNA-binding domain and shares similarity with phage cI transcriptional regulator.; hypothetical protein 1365666 6762103 Sez_1326 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123675.1 1365457 D 552526 CDS YP_002123676.1 195978432 6762101 complement(1367462..1368136) 1 NC_011134.1 similar to ref|YP_602418.1| hypothetical protein MGAS10750_Spy0924 [Streptococcus pyogenes MGAS10750]; ly involved in mediating bacterial immunity to mobile genetic elements such as phages and ICEs.; CRISPR associated protein Csn2 1368136 csn2 6762101 csn2 Streptococcus equi subsp. zooepidemicus MGCS10565 CRISPR associated protein Csn2 YP_002123676.1 1367462 R 552526 CDS YP_002123677.1 195978433 6762102 complement(1368129..1368452) 1 NC_011134.1 similar to ref|NP_269217.1| hypothetical protein SPy_1048 [Streptococcus pyogenes M1 GAS]; ly involved in mediating bacterial immunity to mobile genetic elements such as phages and ICEs.; CRISPR assocaiated protein Cas2 1368452 cas2 6762102 cas2 Streptococcus equi subsp. zooepidemicus MGCS10565 CRISPR assocaiated protein Cas2 YP_002123677.1 1368129 R 552526 CDS YP_002123678.1 195978434 6762122 complement(1368470..1369339) 1 NC_011134.1 similar to ref|NP_721763.1| hypothetical protein SMU.1404c [Streptococcus mutans UA159]; ly involved in mediating bacterial immunity to mobile genetic elements such as phages and ICEs.; CRISPR-associated protein Cas1 1369339 cas1 6762122 cas1 Streptococcus equi subsp. zooepidemicus MGCS10565 CRISPR-associated protein Cas1 YP_002123678.1 1368470 R 552526 CDS YP_002123679.1 195978435 6762114 complement(1369339..1373385) 1 NC_011134.1 similar to ref|YP_282132.1| hypothetical cytosolic protein [Streptococcus pyogenes MGAS5005]; ly involved in mediating bacterial immunity to mobile genetic elements such as phages and ICEs.; CRISPR-Associated Protein Csn1 1373385 csn1 6762114 csn1 Streptococcus equi subsp. zooepidemicus MGCS10565 CRISPR-Associated Protein Csn1 YP_002123679.1 1369339 R 552526 CDS YP_002123680.1 195978436 6762110 complement(1373899..1374060) 1 NC_011134.1 similar to ref|YP_012695.1| hypothetical protein LMOf2365_0084 [Listeria monocytogenes str. 4b F2365]; Possible undefined CRISPR-associated protein.; hypothetical protein 1374060 6762110 Sez_1331 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123680.1 1373899 R 552526 CDS YP_002123681.1 195978437 6762100 complement(1374223..1374885) 1 NC_011134.1 similar to ref|YP_012695.1| hypothetical protein LMOf2365_0084 [Listeria monocytogenes str. 4b F2365]; Lmo0066 homolog within ESAT-6 gene cluster, similarity to ADP-ribosylating toxins.; hypothetical protein 1374885 6762100 Sez_1332 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123681.1 1374223 R 552526 CDS YP_002123682.1 195978438 6762094 complement(1374915..1375610) 1 NC_011134.1 similar to ref|YP_001035282.1| hypothetical protein SSA_1333 [Streptococcus sanguinis SK36]; hypothetical protein 1375610 6762094 Sez_1333 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123682.1 1374915 R 552526 CDS YP_002123683.1 195978439 6762088 complement(1375676..1376896) 1 NC_011134.1 similar to ref|ZP_02093553.1| hypothetical protein PEPMIC_00304 [Peptostreptococcus micros ATCC 33270]; hypothetical protein 1376896 6762088 Sez_1334 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123683.1 1375676 R 552526 CDS YP_002123684.1 195978440 6762086 complement(1376966..1377388) 1 NC_011134.1 similar to ref|YP_820678.1| hypothetical protein STER_1302 [Streptococcus thermophilus LMD-9]; hypothetical protein 1377388 6762086 Sez_1335 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123684.1 1376966 R 552526 CDS YP_002123685.1 195978441 6762083 complement(1377578..1377982) 1 NC_011134.1 similar to ref|XP_001303410.1| Gene info Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase [Trichomonas vaginalis G3]; hypothetical protein 1377982 6762083 Sez_1336 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123685.1 1377578 R 552526 CDS YP_002123686.1 195978442 6762078 complement(1377991..1379166) 1 NC_011134.1 similar to ref|ZP_02093553.1| hypothetical protein PEPMIC_00304 [Peptostreptococcus micros ATCC 33270]; Lmo0066 homolog within ESAT-6 gene cluster, similarity to ADP-ribosylating toxins.; hypothetical protein 1379166 6762078 Sez_1337 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123686.1 1377991 R 552526 CDS YP_002123687.1 195978443 6762073 complement(1379781..1380560) 1 NC_011134.1 similar to ref|YP_906161.1| conserved alanine and proline rich protein [Mycobacterium ulcerans Agy99]; hypothetical protein 1380560 6762073 Sez_1338 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123687.1 1379781 R 552526 CDS YP_002123688.1 195978444 6762071 complement(1380689..1381111) 1 NC_011134.1 similar to gb|EDS33976.1| calpain [Culex pipiens quinquefasciatus]; Unknown, possible calpain-like cysteine proteiase.; hypothetical protein 1381111 6762071 Sez_1339 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123688.1 1380689 R 552526 CDS YP_002123689.1 195978445 6762062 complement(1381093..1382358) 1 NC_011134.1 similar to ref|ZP_02093553.1| hypothetical protein PEPMIC_00304 [Peptostreptococcus micros ATCC 33270]; hypothetical protein 1382358 6762062 Sez_1340 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123689.1 1381093 R 552526 CDS YP_002123690.1 195978446 6762040 complement(1382334..1383125) 1 NC_011134.1 similar to ref|ZP_02093553.1| hypothetical protein PEPMIC_00304 [Peptostreptococcus micros ATCC 33270]; hypothetical protein 1383125 6762040 Sez_1341 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123690.1 1382334 R 552526 CDS YP_002123691.1 195978447 6762052 complement(1383725..1384528) 1 NC_011134.1 similar to ref|NP_268574.1| transposase, IS861 [Streptococcus pyogenes M1 GAS]; transposase IS861 orfB 1384528 6762052 Sez_1342 Streptococcus equi subsp. zooepidemicus MGCS10565 transposase IS861 orfB YP_002123691.1 1383725 R 552526 CDS YP_002123692.1 195978448 6762053 complement(1384552..1385067) 1 NC_011134.1 similar to ref|YP_602677.1| Transposase [Streptococcus pyogenes MGAS10750]; transposase IS861 orfA 1385067 6762053 Sez_1343 Streptococcus equi subsp. zooepidemicus MGCS10565 transposase IS861 orfA YP_002123692.1 1384552 R 552526 CDS YP_002123693.1 195978449 6762048 complement(1385175..1386080) 1 NC_011134.1 similar to ref|NP_664225.1| hypothetical protein SpyM3_0421 [Streptococcus pyogenes MGAS315]; 2-haloalkanoic acid dehalogenase 1386080 6762048 Sez_1344 Streptococcus equi subsp. zooepidemicus MGCS10565 2-haloalkanoic acid dehalogenase YP_002123693.1 1385175 R 552526 CDS YP_002123694.1 195978450 6762032 complement(1386392..1387825) 1 NC_011134.1 similar to ref|NP_688697.1| drug resistance transporter, EmrB/QacA family [Streptococcus agalactiae 2603V/R]; Translocase that confers resistance to substances of high hydrophobicity.; multidrug resistance protein 1387825 6762032 Sez_1345 Streptococcus equi subsp. zooepidemicus MGCS10565 multidrug resistance protein YP_002123694.1 1386392 R 552526 CDS YP_002123695.1 195978451 6762043 1388200..1389705 1 NC_011134.1 class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1; lysyl-tRNA synthetase 1389705 lysS 6762043 lysS Streptococcus equi subsp. zooepidemicus MGCS10565 lysyl-tRNA synthetase YP_002123695.1 1388200 D 552526 CDS YP_002123696.1 195978452 6762035 complement(1389856..1389993) 1 NC_011134.1 hypothetical protein 1389993 6762035 Sez_1347 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123696.1 1389856 R 552526 CDS YP_002123697.1 195978453 6762017 1390109..1390249 1 NC_011134.1 hypothetical protein 1390249 6762017 Sez_1348 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123697.1 1390109 D 552526 CDS YP_002123698.1 195978454 6762024 complement(1391147..1391359) 1 NC_011134.1 similar to ref|YP_602006.1| hypothetical cytosolic protein [Streptococcus pyogenes MGAS10750]; Unknown, bacterial seryl-tRNA synthetase related.; hypothetical protein 1391359 6762024 Sez_1349 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123698.1 1391147 R 552526 CDS YP_002123699.1 195978455 6762011 complement(1391492..1391620) 1 NC_011134.1 hypothetical protein 1391620 6762011 Sez_1350 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123699.1 1391492 R 552526 CDS YP_002123700.1 195978456 6761997 1391621..1391794 1 NC_011134.1 hypothetical protein 1391794 6761997 Sez_1351 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123700.1 1391621 D 552526 CDS YP_002123701.1 195978457 6762004 complement(1391890..1393176) 1 NC_011134.1 similar to ref|ZP_00365935.1| COG0826: Collagenase and related proteases [Streptococcus pyogenes M49 591]; The hydrolysis of a peptide bond or bonds within a protein.; peptidase U32 1393176 6762004 Sez_1352 Streptococcus equi subsp. zooepidemicus MGCS10565 peptidase U32 YP_002123701.1 1391890 R 552526 CDS YP_002123702.1 195978458 6762000 complement(1393284..1394210) 1 NC_011134.1 similar to ref|ZP_00365936.1| COG0826: Collagenase and related proteases [Streptococcus pyogenes M49 591]; peptidase U32 1394210 6762000 Sez_1353 Streptococcus equi subsp. zooepidemicus MGCS10565 peptidase U32 YP_002123702.1 1393284 R 552526 CDS YP_002123703.1 195978459 6761980 1394312..1394647 1 NC_011134.1 similar to ref|ZP_00365937.1| COG0477: Permeases of the major facilitator superfamily [Streptococcus pyogenes M49 591]; hypothetical protein 1394647 6761980 Sez_1354 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123703.1 1394312 D 552526 CDS YP_002123704.1 195978460 6761976 complement(1394779..1395198) 1 NC_011134.1 similar to gb|ABF37458.1| hypothetical exported protein [Streptococcus pyogenes MGAS10750]; hypothetical protein 1395198 6761976 Sez_1355 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123704.1 1394779 R 552526 CDS YP_002123705.1 195978461 6761991 complement(1395195..1395599) 1 NC_011134.1 similar to ref|ZP_00365939.1| COG4768: Uncharacterized protein containing a divergent version of the methyl-accepting chemotaxis-like domain [Streptococcus pyogenes M49 591]; general stress protein 1395599 6761991 Sez_1356 Streptococcus equi subsp. zooepidemicus MGCS10565 general stress protein YP_002123705.1 1395195 R 552526 CDS YP_002123706.1 195978462 6761983 complement(1395621..1396400) 1 NC_011134.1 transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein; prolipoprotein diacylglyceryl transferase 1396400 lgt 6761983 lgt Streptococcus equi subsp. zooepidemicus MGCS10565 prolipoprotein diacylglyceryl transferase YP_002123706.1 1395621 R 552526 CDS YP_002123707.1 195978463 6761981 complement(1396397..1397329) 1 NC_011134.1 catalyzes the phosphorylation of the phosphocarrier protein HPr of the bacterial phosphotransferase system; HPr kinase/phosphorylase 1397329 hprK 6761981 hprK Streptococcus equi subsp. zooepidemicus MGCS10565 HPr kinase/phosphorylase YP_002123707.1 1396397 R 552526 CDS YP_002123708.1 195978464 6761975 complement(1397607..1397879) 1 NC_011134.1 stress-responsive transcriptional regulator; similar to ref|YP_059824.1| stress-responsive transcriptional regulator [Streptococcus pyogenes MGAS10394]; phage shock protein C 1397879 6761975 Sez_1359 Streptococcus equi subsp. zooepidemicus MGCS10565 phage shock protein C YP_002123708.1 1397607 R 552526 CDS YP_002123709.1 195978465 6761958 complement(1397943..1398380) 1 NC_011134.1 similar to gb|ABF31661.1| metallopeptidase, SprT family [Streptococcus pyogenes MGAS9429]; hypothetical protein 1398380 6761958 Sez_1360 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123709.1 1397943 R 552526 CDS YP_002123710.1 195978466 6761969 complement(1398367..1400499) 1 NC_011134.1 similar to ref|YP_601996.1| transcription accessory protein [Streptococcus pyogenes MGAS10750]; S1 RNA-binding domain transcription accessory protein 1400499 6761969 Sez_1361 Streptococcus equi subsp. zooepidemicus MGCS10565 S1 RNA-binding domain transcription accessory protein YP_002123710.1 1398367 R 552526 CDS YP_002123711.1 195978467 6761948 1400914..1402635 1 NC_011134.1 similar to ref|ZP_01371554.1| transposase, IS4 [Desulfitobacterium hafniense DCB-2]; transposase IS4-like 1402635 6761948 Sez_1362 Streptococcus equi subsp. zooepidemicus MGCS10565 transposase IS4-like YP_002123711.1 1400914 D 552526 CDS YP_002123712.1 195978468 6761962 complement(1402791..1403117) 1 NC_011134.1 similar to ref|YP_601318.1| hypothetical protein MGAS2096_Spy1722 [Streptococcus pyogenes MGAS2096]; hypothetical protein 1403117 6761962 Sez_1363 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123712.1 1402791 R 552526 CDS YP_002123713.1 195978469 6761954 complement(1403390..1404142) 1 NC_011134.1 ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation; phosphate transporter ATP-binding protein 1404142 pstB 6761954 pstB Streptococcus equi subsp. zooepidemicus MGCS10565 phosphate transporter ATP-binding protein YP_002123713.1 1403390 R 552526 CDS YP_002123714.1 195978470 6761935 complement(1404144..1404959) 1 NC_011134.1 similar to ref|ZP_01825632.1| phosphate ABC transporter, permease [Streptococcus pneumoniae SP11-BS70]; Part of the binding-protein-dependent transport system. Probably responsible for the translocation of the substrate across the membrane.; phosphate ABC transporter permease 1404959 pstA 6761935 pstA Streptococcus equi subsp. zooepidemicus MGCS10565 phosphate ABC transporter permease YP_002123714.1 1404144 R 552526 CDS YP_002123715.1 195978471 6761934 complement(1404952..1405815) 1 NC_011134.1 similar to ref|NP_346505.1| phosphate ABC transporter, permease [Streptococcus pneumoniae TIGR4]; Part of the binding-protein-dependent transport system. Probably responsible for the translocation of the substrate across the membrane.; phosphate ABC transporter permease 1405815 pstC 6761934 pstC Streptococcus equi subsp. zooepidemicus MGCS10565 phosphate ABC transporter permease YP_002123715.1 1404952 R 552526 CDS YP_002123716.1 195978472 6761928 complement(1405885..1406757) 1 NC_011134.1 similar to ref|NP_359486.1| ABC transporter substrate-binding protein - phosphate transport [Streptococcus pneumoniae R6]; Part of a binding-protein-dependent transport system.; phosphate ABC transporter substrate-binding protein 1406757 pstS 6761928 pstS Streptococcus equi subsp. zooepidemicus MGCS10565 phosphate ABC transporter substrate-binding protein YP_002123716.1 1405885 R 552526 CDS YP_002123717.1 195978473 6761925 complement(1406916..1408214) 1 NC_011134.1 similar to ref|ZP_01817667.1| sensor histidine kinase PnpS [Streptococcus pneumoniae SP3-BS71]; Member of the two-component regulatory system phoP/phoR involved in the alkaline phosphatases genes regulation. PhoR may function as a membrane-associated protein kinase that phosphorylates phoP in response to environmental signals.; alkaline phosphatase synthesis sensor protein PhoR 1408214 phoR 6761925 phoR Streptococcus equi subsp. zooepidemicus MGCS10565 alkaline phosphatase synthesis sensor protein PhoR YP_002123717.1 1406916 R 552526 CDS YP_002123718.1 195978474 6761919 complement(1408225..1408968) 1 NC_011134.1 similar to ref|ZP_01817666.1| response regulator [Streptococcus pneumoniae SP3-BS71]; Member of the two-component regulatory system phoP/phoR involved in the regulation of alkaline phosphatase genes phoA and phoB and of phosphodiesterase.; alkaline phosphatase synthesis transcriptional regulatory protein PhoP 1408968 phoP 6761919 phoP Streptococcus equi subsp. zooepidemicus MGCS10565 alkaline phosphatase synthesis transcriptional regulatory protein PhoP YP_002123718.1 1408225 R 552526 CDS YP_002123719.1 195978475 6761930 1409119..1409274 1 NC_011134.1 similar to ref|NP_268841.1| hypothetical protein SPy_0577 [Streptococcus pyogenes M1 GAS]; hypothetical protein 1409274 6761930 Sez_1370 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123719.1 1409119 D 552526 CDS YP_002123720.1 195978476 6761926 1409315..1410217 1 NC_011134.1 similar to ref|YP_279928.1| hypothetical membrane spanning protein [Streptococcus pyogenes MGAS6180]; hypothetical protein 1410217 6761926 Sez_1371 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123720.1 1409315 D 552526 CDS YP_002123721.1 195978477 6761899 1410217..1410474 1 NC_011134.1 similar to ref|YP_279927.1| hypothetical membrane spanning protein [Streptococcus pyogenes MGAS6180]; hypothetical protein 1410474 6761899 Sez_1372 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123721.1 1410217 D 552526 CDS YP_002123722.1 195978478 6761916 1410468..1411034 1 NC_011134.1 similar to ref|YP_059819.1| Hypothetical membrane spanning protein [Streptococcus pyogenes MGAS10394]; hypothetical protein 1411034 6761916 Sez_1373 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123722.1 1410468 D 552526 CDS YP_002123723.1 195978479 6761914 complement(1411219..1412640) 1 NC_011134.1 similar to ref|YP_281839.1| 6-phospho-beta-glucosidase [Streptococcus pyogenes MGAS5005]; Can Hydrolyze Salicin And Arbutin.; 6-phospho-beta-glucosidase 1412640 6761914 Sez_1374 Streptococcus equi subsp. zooepidemicus MGCS10565 6-phospho-beta-glucosidase YP_002123723.1 1411219 R 552526 CDS YP_002123724.1 195978480 6761902 complement(1412667..1413722) 1 NC_011134.1 similar to ref|YP_001128925.1| beta-glucoside-specific phosphotransferase system (PTS), IIABC component [Streptococcus pyogenes str. Manfredo]; The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. This system is involved in arbutin, cellobiose, and salicin transport.; PTS system arbutin-, cellobiose-, and salicin-specific transporter subunit IIBC 1413722 6761902 Sez_1375 Streptococcus equi subsp. zooepidemicus MGCS10565 PTS system arbutin-, cellobiose-, and salicin-specific transporter subunit IIBC YP_002123724.1 1412667 R 552526 CDS YP_002123725.1 195978481 6761877 complement(1413704..1414528) 1 NC_011134.1 similar to ref|ZP_00365852.1| COG1263: Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Streptococcus pyogenes M49 591]; The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. This system is involved in beta-glucoside transport.; PTS system beta-glucoside-specific transporter subunit IIBCA 1414528 6761877 Sez_1376 Streptococcus equi subsp. zooepidemicus MGCS10565 PTS system beta-glucoside-specific transporter subunit IIBCA YP_002123725.1 1413704 R 552526 CDS YP_002123726.1 195978482 6761897 complement(1414533..1415372) 1 NC_011134.1 similar to ref|YP_281837.1| transcription antiterminator, BglG family [Streptococcus pyogenes MGAS5005]; Mediates positive regulation by functioning as an antiterminator factor of transcription.; transcription antiterminator 1415372 6761897 Sez_1377 Streptococcus equi subsp. zooepidemicus MGCS10565 transcription antiterminator YP_002123726.1 1414533 R 552526 CDS YP_002123727.1 195978483 6761872 complement(1415661..1417118) 1 NC_011134.1 similar to ref|YP_601988.1| Cell division protein ftsY [Streptococcus pyogenes MGAS10750]; Required for normal cell growth and morphogenesis; translocation of at least 1 protein is impaired in its absence.; signal recognition particle receptor protein FtsY subunit alpha 1417118 ftsY 6761872 ftsY Streptococcus equi subsp. zooepidemicus MGCS10565 signal recognition particle receptor protein FtsY subunit alpha YP_002123727.1 1415661 R 552526 CDS YP_002123728.1 195978484 6761888 complement(1417118..1417945) 1 NC_011134.1 similar to ref|YP_059813.1| Hydrolase (HAD superfamily) [Streptococcus pyogenes MGAS10394]; hydrolase HAD superfamily 1417945 6761888 Sez_1379 Streptococcus equi subsp. zooepidemicus MGCS10565 hydrolase HAD superfamily YP_002123728.1 1417118 R 552526 CDS YP_002123729.1 195978485 6761860 complement(1417946..1418743) 1 NC_011134.1 similar to ref|YP_001128930.1| haloacid dehalogenase-like hydrolase [Streptococcus pyogenes str. Manfredo]; hydrolase HAD superfamily 1418743 6761860 Sez_1380 Streptococcus equi subsp. zooepidemicus MGCS10565 hydrolase HAD superfamily YP_002123729.1 1417946 R 552526 CDS YP_002123730.1 195978486 6761879 complement(1418946..1419134) 1 NC_011134.1 hypothetical protein 1419134 6761879 Sez_1381 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123730.1 1418946 R 552526 CDS YP_002123731.1 195978487 6761874 complement(1419261..1419710) 1 NC_011134.1 similar to ref|YP_001036160.1| hypothetical protein SSA_2248 [Streptococcus sanguinis SK36]; hypothetical protein 1419710 6761874 Sez_1382 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123731.1 1419261 R 552526 CDS YP_002123732.1 195978488 6761852 complement(1419767..1420390) 1 NC_011134.1 similar to ref|YP_599261.1| ABC transporter ATP-binding protein [Streptococcus pyogenes MGAS10270]; ABC transporter ATP-binding protein 1420390 6761852 Sez_1383 Streptococcus equi subsp. zooepidemicus MGCS10565 ABC transporter ATP-binding protein YP_002123732.1 1419767 R 552526 CDS YP_002123733.1 195978489 6761869 complement(1420453..1422372) 1 NC_011134.1 similar to ref|YP_001036162.1| ABC-type antimicrobial peptide transporter, permease component, [Streptococcus sanguinis SK36]; ABC transporter permease 1422372 6761869 Sez_1384 Streptococcus equi subsp. zooepidemicus MGCS10565 ABC transporter permease YP_002123733.1 1420453 R 552526 CDS YP_002123734.1 195978490 6761863 complement(1422439..1422744) 1 NC_011134.1 similar to gb|ABF34719.1| hypothetical exported protein [Streptococcus pyogenes MGAS10270]; hypothetical protein 1422744 6761863 Sez_1385 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123734.1 1422439 R 552526 CDS YP_002123735.1 195978491 6761855 complement(1422911..1423204) 1 NC_011134.1 hypothetical protein 1423204 6761855 Sez_1386 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123735.1 1422911 R 552526 CDS YP_002123736.1 195978492 6761853 complement(1423210..1424469) 1 NC_011134.1 similar to ref|ZP_00874485.1| Lipase, class 3 [Streptococcus suis 89/1591]; hypothetical protein 1424469 6761853 Sez_1387 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123736.1 1423210 R 552526 CDS YP_002123737.1 195978493 6761850 complement(1424501..1425016) 1 NC_011134.1 similar to ref|ZP_00780318.1| conserved hypothetical protein [Streptococcus agalactiae 18RS21]; hypothetical protein 1425016 6761850 Sez_1388 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123737.1 1424501 R 552526 CDS YP_002123738.1 195978494 6761849 complement(1425067..1425510) 1 NC_011134.1 similar to ref|ZP_00780318.1| conserved hypothetical protein [Streptococcus agalactiae 18RS21]; hypothetical protein 1425510 6761849 Sez_1389 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123738.1 1425067 R 552526 CDS YP_002123739.1 195978495 6761846 complement(1425877..1429428) 1 NC_011134.1 similar to ref|ZP_00366640.1| COG1196: Chromosome segregation ATPases [Streptococcus pyogenes M49 591]; Plays an important role in chromosome structure and partitioning. Essential for chromosome partition.; chromosome partition protein Smc 1429428 smc 6761846 smc Streptococcus equi subsp. zooepidemicus MGCS10565 chromosome partition protein Smc YP_002123739.1 1425877 R 552526 CDS YP_002123740.1 195978496 6761843 complement(1429429..1430124) 1 NC_011134.1 cytoplasmic enzyme involved in processing rRNA and some mRNAs; substrates typically have dsRNA regions; forms a homodimer; have N-terminal nuclease and C-terminal RNA-binding domains; requires magnesium as preferred ion for activity; ribonuclease III 1430124 rnc 6761843 rnc Streptococcus equi subsp. zooepidemicus MGCS10565 ribonuclease III YP_002123740.1 1429429 R 552526 CDS YP_002123741.1 195978497 6761814 complement(1430380..1431195) 1 NC_011134.1 similar to ref|YP_597797.1| Transcriptional regulator [Streptococcus pyogenes MGAS10270]; transcriptional regulator RofA-like protein (RALP) 1431195 6761814 Sez_1392 Streptococcus equi subsp. zooepidemicus MGCS10565 transcriptional regulator RofA-like protein (RALP) YP_002123741.1 1430380 R 552526 CDS YP_002123742.1 195978498 6761832 complement(1431196..1431894) 1 NC_011134.1 similar to ref|YP_001127764.1| regulatory protein-RofA related [Streptococcus pyogenes str. Manfredo]; transcriptional regulator RofA-like protein (RALP) 1431894 6761832 Sez_1393 Streptococcus equi subsp. zooepidemicus MGCS10565 transcriptional regulator RofA-like protein (RALP) YP_002123742.1 1431196 R 552526 CDS YP_002123743.1 195978499 6760964 complement(1432774..1433583) 1 NC_011134.1 similar to ref|YP_059789.1| Zn-dependent hydrolase (beta-lactamase superfamily) [Streptococcus pyogenes MGAS10394]; Zn-dependent hydrolase (beta-lactamase superfamily) 1433583 6760964 Sez_1394 Streptococcus equi subsp. zooepidemicus MGCS10565 Zn-dependent hydrolase (beta-lactamase superfamily) YP_002123743.1 1432774 R 552526 CDS YP_002123744.1 195978500 6760966 complement(1433587..1434939) 1 NC_011134.1 similar to ref|YP_600051.1| Two-component sensor histidine kinase VicK [Streptococcus pyogenes MGAS2096]; TCS sensor kinase VicK 1434939 vicK 6760966 vicK Streptococcus equi subsp. zooepidemicus MGCS10565 TCS sensor kinase VicK YP_002123744.1 1433587 R 552526 CDS YP_002123745.1 195978501 6760990 complement(1434932..1435642) 1 NC_011134.1 similar to emb|CAB65451.1| VicR protein [Streptococcus pyogenes]; TCS response regulator VicR 1435642 vicR 6760990 vicR Streptococcus equi subsp. zooepidemicus MGCS10565 TCS response regulator VicR YP_002123745.1 1434932 R 552526 CDS YP_002123746.1 195978502 6760958 complement(1435839..1436858) 1 NC_011134.1 similar to ref|YP_596165.1| hypothetical cytosolic protein [Streptococcus pyogenes MGAS9429]; hypothetical protein 1436858 6760958 Sez_1397 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123746.1 1435839 R 552526 CDS YP_002123747.1 195978503 6760984 complement(1436904..1438166) 1 NC_011134.1 similar to ref|YP_600048.1| Long-chain-fatty-acid--CoA ligase [Streptococcus pyogenes MGAS2096]; Catalysis of the reaction: ATP + a long-chain carboxylic acid + CoA = AMP + diphosphate + an acyl-CoA; long-chain fatty acids have chain lengths of C12-18.; long-chain-fatty-acid--CoA ligase 1438166 6760984 Sez_1398 Streptococcus equi subsp. zooepidemicus MGCS10565 long-chain-fatty-acid--CoA ligase YP_002123747.1 1436904 R 552526 CDS YP_002123748.1 195978504 6760978 complement(1438156..1439271) 1 NC_011134.1 similar to ref|ZP_00366633.1| COG0183: Acetyl-CoA acetyltransferase [Streptococcus pyogenes M49 591]; Thiolytic cleavage of beta-ketoadipyl-CoA to succinate and acetyl-CoA (by similarity).; acetyl-CoA C-acetyltransferase 1439271 6760978 Sez_1399 Streptococcus equi subsp. zooepidemicus MGCS10565 acetyl-CoA C-acetyltransferase YP_002123748.1 1438156 R 552526 CDS YP_002123749.1 195978505 6760982 complement(1439268..1439807) 1 NC_011134.1 similar to ref|NP_606782.1| hypothetical protein spyM18_0589 [Streptococcus pyogenes MGAS8232]; hypothetical protein 1439807 6760982 Sez_1400 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123749.1 1439268 R 552526 CDS YP_002123750.1 195978506 6760972 complement(1439916..1440065) 1 NC_011134.1 hypothetical protein 1440065 6760972 Sez_1401 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123750.1 1439916 R 552526 CDS YP_002123751.1 195978507 6760979 complement(1440281..1441042) 1 NC_011134.1 similar to ref|YP_279887.1| ABC transporter permease [Streptococcus pyogenes MGAS6180]; multidrug ABC transporter permease 1441042 6760979 Sez_1402 Streptococcus equi subsp. zooepidemicus MGCS10565 multidrug ABC transporter permease YP_002123751.1 1440281 R 552526 CDS YP_002123752.1 195978508 6760968 complement(1441068..1441886) 1 NC_011134.1 similar to ref|YP_601937.1| Daunorubicin resistance transmembrane protein [Streptococcus pyogenes MGAS10750]; multidrug ABC transporter permease 1441886 6760968 Sez_1403 Streptococcus equi subsp. zooepidemicus MGCS10565 multidrug ABC transporter permease YP_002123752.1 1441068 R 552526 CDS YP_002123753.1 195978509 6760977 complement(1441888..1442880) 1 NC_011134.1 similar to ref|ZP_00783216.1| ABC transporter, ATP-binding protein [Streptococcus agalactiae H36B]; ATP-binding transport protein 1442880 6760977 Sez_1404 Streptococcus equi subsp. zooepidemicus MGCS10565 ATP-binding transport protein YP_002123753.1 1441888 R 552526 CDS YP_002123754.1 195978510 6760969 complement(1443162..1445129) 1 NC_011134.1 catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr); threonyl-tRNA synthetase 1445129 thrS 6760969 thrS Streptococcus equi subsp. zooepidemicus MGCS10565 threonyl-tRNA synthetase YP_002123754.1 1443162 R 552526 CDS YP_002123755.1 195978511 6762331 complement(1445683..1447017) 1 NC_011134.1 similar to ref|YP_279883.1| 1,2-diacylglycerol 3-glucosyltransferase [Streptococcus pyogenes MGAS6180]; 1,2-diacylglycerol 3-glucosyltransferase 1447017 6762331 Sez_1406 Streptococcus equi subsp. zooepidemicus MGCS10565 1,2-diacylglycerol 3-glucosyltransferase YP_002123755.1 1445683 R 552526 CDS YP_002123756.1 195978512 6762333 complement(1447019..1448017) 1 NC_011134.1 similar to ref|YP_279882.1| glycosyltransferase [Streptococcus pyogenes MGAS6180]; glycosyltransferase 1448017 6762333 Sez_1407 Streptococcus equi subsp. zooepidemicus MGCS10565 glycosyltransferase YP_002123756.1 1447019 R 552526 CDS YP_002123757.1 195978513 6762310 complement(1448087..1448212) 1 NC_011134.1 hypothetical protein 1448212 6762310 Sez_1408 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123757.1 1448087 R 552526 CDS YP_002123758.1 195978514 6762311 complement(1448314..1449771) 1 NC_011134.1 converts 1,4-alpha-D-glucans to maltodextrin; alpha-amylase 1449771 amyS 6762311 amyS Streptococcus equi subsp. zooepidemicus MGCS10565 alpha-amylase YP_002123758.1 1448314 R 552526 CDS YP_002123759.1 195978515 6762330 complement(1449859..1450860) 1 NC_011134.1 similar to gb|ABL07487.1| catabolite control protein A [Streptococcus equi subsp. zooepidemicus]; Transcriptional regulator involved in both the repression of carbohydrate utilization genes and in the positive regulation of genes involved in excretion of excess carbon.; catabolite control protein A CCpA 1450860 ccpA 6762330 ccpA Streptococcus equi subsp. zooepidemicus MGCS10565 catabolite control protein A CCpA YP_002123759.1 1449859 R 552526 CDS YP_002123760.1 195978516 6762339 1452182..1452340 1 NC_011134.1 hypothetical protein 1452340 6762339 Sez_1413 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123760.1 1452182 D 552526 CDS YP_002123761.1 195978517 6762340 1452488..1453156 1 NC_011134.1 similar to ref|NP_268790.1| NAD(P)H-flavin oxidoreductase [Streptococcus pyogenes M1 GAS]; oxygen-insensitive NAD(P)H nitroreductase / dihydropteridine reductase 1453156 6762340 Sez_1414 Streptococcus equi subsp. zooepidemicus MGCS10565 oxygen-insensitive NAD(P)H nitroreductase / dihydropteridine reductase YP_002123761.1 1452488 D 552526 CDS YP_002123762.1 195978518 6762338 1453264..1454196 1 NC_011134.1 similar to ref|YP_598030.1| Bactoprenol glucosyl transferase [Streptococcus pyogenes MGAS10270]; Catalyzes the transfer of the glucose residue from UDP-glucose to a lipid carrier (by similarity).; bactoprenol glucosyl transferase 1454196 6762338 Sez_1415 Streptococcus equi subsp. zooepidemicus MGCS10565 bactoprenol glucosyl transferase YP_002123762.1 1453264 D 552526 CDS YP_002123763.1 195978519 6762336 complement(1454180..1454305) 1 NC_011134.1 hypothetical protein 1454305 6762336 Sez_1416 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123763.1 1454180 R 552526 CDS YP_002123764.1 195978520 6762318 complement(1454483..1454950) 1 NC_011134.1 binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation; SsrA-binding protein 1454950 smpB 6762318 smpB Streptococcus equi subsp. zooepidemicus MGCS10565 SsrA-binding protein YP_002123764.1 1454483 R 552526 CDS YP_002123765.1 195978521 6762335 complement(1454953..1457277) 1 NC_011134.1 similar to ref|YP_601921.1| Exoribonuclease II [Streptococcus pyogenes MGAS10750]; 3'-5'exoribonuclease that participates in an essential cell function. Acts nonspecifically on poly(A), poly(U) and ribosomal RNAs.; ribonuclease R Rnr 1457277 rnr 6762335 rnr Streptococcus equi subsp. zooepidemicus MGCS10565 ribonuclease R Rnr YP_002123765.1 1454953 R 552526 CDS YP_002123766.1 195978522 6760976 complement(1457364..1457600) 1 NC_011134.1 similar to ref|NP_606756.1| preprotein translocase subunit SecG [Streptococcus pyogenes MGAS8232]; preprotein translocase subunit SecG 1457600 secG 6760976 secG Streptococcus equi subsp. zooepidemicus MGCS10565 preprotein translocase subunit SecG YP_002123766.1 1457364 R 552526 CDS YP_002123767.1 195978523 6762324 complement(1457808..1457936) 1 NC_011134.1 hypothetical protein 1457936 6762324 Sez_1420 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123767.1 1457808 R 552526 CDS YP_002123768.1 195978524 6760965 1458393..1459889 1 NC_011134.1 similar to emb|CAA68254.1| fibronectin-binding protein [Streptococcus equi]; Possible fibronectin-binding adhesin, has a collagen-structural-motif domain composed of 41 Gly-Xaa-Yaa repeats.; hypothetical protein 1459889 sclZ.9 6760965 sclZ.9 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123768.1 1458393 D 552526 CDS YP_002123769.1 195978525 6760992 complement(1460044..1460637) 1 NC_011134.1 similar to ref|YP_059753.1| dephospho-CoA kinase [Streptococcus pyogenes MGAS10394]; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.; dephospho-CoA kinase CoaE 1460637 coaE 6760992 coaE Streptococcus equi subsp. zooepidemicus MGCS10565 dephospho-CoA kinase CoaE YP_002123769.1 1460044 R 552526 CDS YP_002123770.1 195978526 6760993 complement(1460637..1461527) 1 NC_011134.1 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases; formamidopyrimidine-DNA glycosylase 1461527 mutM 6760993 mutM Streptococcus equi subsp. zooepidemicus MGCS10565 formamidopyrimidine-DNA glycosylase YP_002123770.1 1460637 R 552526 CDS YP_002123771.1 195978527 6760981 complement(1461929..1463728) 1 NC_011134.1 similar to ref|ZP_00875460.1| Beta-galactosidase [Streptococcus suis 89/1591]; Preferentially hydrolyzes beta(1->3) galactosyl linkages over beta(1->4) linkages.; beta-galactosidase precursor Bga 1463728 bga 6760981 bga Streptococcus equi subsp. zooepidemicus MGCS10565 beta-galactosidase precursor Bga YP_002123771.1 1461929 R 552526 CDS YP_002123772.1 195978528 6760987 complement(1463854..1468494) 1 NC_011134.1 similar to ref|ZP_01968534.1| hypothetical protein RUMTOR_02111 [Ruminococcus torques ATCC 27756]; Catalysis of the hydrolysis of alpha-(2->3)-, alpha-(2->6)-, alpha-(2->8)-glycosidic linkages of terminal sialic residues in oligosaccharides, glycoproteins, glycolipids, colominic acid and synthetic substrates.; sialidase NanA-like 1468494 nanA 6760987 nanA Streptococcus equi subsp. zooepidemicus MGCS10565 sialidase NanA-like YP_002123772.1 1463854 R 552526 CDS YP_002123773.1 195978529 6760975 complement(1468669..1470027) 1 NC_011134.1 similar to ref|ZP_01817544.1| Phosphotransferase system (PTS) cellobiose-specific, IIC component, [Streptococcus pneumoniae SP3-BS71]; Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + sugar(out) = protein histidine + sugar phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport.; PTS system cellobiose-specific transporter subunit IIC CelC 1470027 celC 6760975 celC Streptococcus equi subsp. zooepidemicus MGCS10565 PTS system cellobiose-specific transporter subunit IIC CelC YP_002123773.1 1468669 R 552526 CDS YP_002123774.1 195978530 6760980 complement(1470078..1471394) 1 NC_011134.1 similar to ref|ZP_01825420.1| phosphotransferase system cellobiose-specific component IIC [Streptococcus pneumoniae SP11-BS70]; The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. This system is involved in cellobiose transport.; cellobiose permease IIC component CelB 1471394 celB 6760980 celB Streptococcus equi subsp. zooepidemicus MGCS10565 cellobiose permease IIC component CelB YP_002123774.1 1470078 R 552526 CDS YP_002123775.1 195978531 6760974 complement(1471387..1471728) 1 NC_011134.1 similar to ref|ZP_00603570.1| Phosphotransferase system PTS, lactose/cellobiose-specific IIA subunit [Enterococcus faecium DO]; This is a component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system. The IIcd domains contain the sugar binding site and the transmembrane channel; the IIa domain contains the primary phosphorylation site (the donor is phospho-Hpr); IIa transfers its phosphoryl group to the IIb domain which finally transfers it to the sugar.; PTS system cellobiose-specific transporter subunit IIA CelA 1471728 celA 6760974 celA Streptococcus equi subsp. zooepidemicus MGCS10565 PTS system cellobiose-specific transporter subunit IIA CelA YP_002123775.1 1471387 R 552526 CDS YP_002123776.1 195978532 6760973 complement(1471729..1472028) 1 NC_011134.1 similar to ref|YP_001034277.1| Phosphotransferase system (PTS) cellobiose-specific component IIB, [Streptococcus sanguinis SK36]; The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. This system is involved in cellobiose transport.; cellobiose-specific phosphotransferase enzyme IIB component 1472028 6760973 Sez_1429 Streptococcus equi subsp. zooepidemicus MGCS10565 cellobiose-specific phosphotransferase enzyme IIB component YP_002123776.1 1471729 R 552526 CDS YP_002123777.1 195978533 6760991 complement(1472070..1472969) 1 NC_011134.1 similar to ref|ZP_02186120.1| hypothetical protein CAT7_00288 [Carnobacterium sp. AT7]; Catalysis of the reaction: L-aspartate-4-semialdehyde + pyruvate = dihydrodipicolinate + 2 H2O.; dihydrodipicolinate synthase 1472969 6760991 Sez_1430 Streptococcus equi subsp. zooepidemicus MGCS10565 dihydrodipicolinate synthase YP_002123777.1 1472070 R 552526 CDS YP_002123778.1 195978534 6760967 1473149..1474351 1 NC_011134.1 similar to ref|YP_001034276.1| ROK family protein, [Streptococcus sanguinis SK36]; Transcriptional repressor of xylose-utilizing enzymes; xylose repressor XylR 1474351 xylR 6760967 xylR Streptococcus equi subsp. zooepidemicus MGCS10565 xylose repressor XylR YP_002123778.1 1473149 D 552526 CDS YP_002123779.1 195978535 6760962 complement(1474514..1475059) 1 NC_011134.1 similar to ref|YP_279846.1| phosphohydrolase [Streptococcus pyogenes MGAS6180]; MutT/nudix family protein 1475059 6760962 Sez_1432 Streptococcus equi subsp. zooepidemicus MGCS10565 MutT/nudix family protein YP_002123779.1 1474514 R 552526 CDS YP_002123780.1 195978536 6760959 complement(1475301..1476632) 1 NC_011134.1 similar to ref|YP_001089191.1| permease [Clostridium difficile 630]; Permease For An Unknown Substrate.; D-beta-hydroxybutyrate permease 1476632 6760959 Sez_1433 Streptococcus equi subsp. zooepidemicus MGCS10565 D-beta-hydroxybutyrate permease YP_002123780.1 1475301 R 552526 CDS YP_002123781.1 195978537 6762352 complement(1476723..1477496) 1 NC_011134.1 catalyzes the formation of acetoacetate from 3-hydroxybutyrate; 3-hydroxybutyrate dehydrogenase 1477496 6762352 Sez_1434 Streptococcus equi subsp. zooepidemicus MGCS10565 3-hydroxybutyrate dehydrogenase YP_002123781.1 1476723 R 552526 CDS YP_002123782.1 195978538 6762347 complement(1477532..1478176) 1 NC_011134.1 similar to ref|YP_599072.1| Acetate CoA-transferase beta subunit [Streptococcus pyogenes MGAS10270]; Catalysis of the reaction: acyl-CoA + acetate = a fatty acid anion + acetyl-CoA.; butyrate--acetoacetate CoA-transferase subunit B 1478176 6762347 Sez_1435 Streptococcus equi subsp. zooepidemicus MGCS10565 butyrate--acetoacetate CoA-transferase subunit B YP_002123782.1 1477532 R 552526 CDS YP_002123783.1 195978539 6760971 complement(1478182..1478814) 1 NC_011134.1 similar to ref|YP_602948.1| Acetate CoA-transferase alpha subunit [Streptococcus pyogenes MGAS10750]; Catalysis of the reaction: acyl-CoA + acetate = a fatty acid anion + acetyl-CoA.; acetate CoA-transferase subunit alpha 1478814 6760971 Sez_1436 Streptococcus equi subsp. zooepidemicus MGCS10565 acetate CoA-transferase subunit alpha YP_002123783.1 1478182 R 552526 CDS YP_002123784.1 195978540 6760983 complement(1478847..1480037) 1 NC_011134.1 similar to ref|YP_597070.1| acetyl-CoA acetyltransferase [Streptococcus pyogenes MGAS9429]; Involved in the production of polyhydroxyalkonic acids (PHAs), composed primarily of 3-hydroxybutyric acid (3HB) and 3- hydroxyvaleric acid (3HV).; 3-ketoacyl-CoA thiolase 1480037 phaA 6760983 phaA Streptococcus equi subsp. zooepidemicus MGCS10565 3-ketoacyl-CoA thiolase YP_002123784.1 1478847 R 552526 CDS YP_002123785.1 195978541 6760960 1480229..1481131 1 NC_011134.1 similar to ref|NP_269683.1| transcriptional regulator (LysR family) [Streptococcus pyogenes M1 GAS]; Positive Regulatory Protein; LysR family transcriptional regulator 1481131 6760960 Sez_1438 Streptococcus equi subsp. zooepidemicus MGCS10565 LysR family transcriptional regulator YP_002123785.1 1480229 D 552526 CDS YP_002123786.1 195978542 6760961 complement(1482029..1482415) 1 NC_011134.1 similar to ref|ZP_00788202.1| membrane protein, [Streptococcus agalactiae CJB111]; hypothetical protein 1482415 6760961 Sez_1439 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123786.1 1482029 R 552526 CDS YP_002123787.1 195978543 6762351 complement(1482758..1482880) 1 NC_011134.1 hypothetical protein 1482880 6762351 Sez_1440 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123787.1 1482758 R 552526 CDS YP_002123788.1 195978544 6762332 complement(1483108..1484004) 1 NC_011134.1 Era; Escherichia coli Ras-like protein; Bex; Bacillus Era-complementing segment; essential protein in Escherichia coli that is involved in many cellular processes; GTPase; binds the cell membrane through apparent C-terminal domain; mutants are arrested during the cell cycle; Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome; GTP-binding protein Era 1484004 era 6762332 era Streptococcus equi subsp. zooepidemicus MGCS10565 GTP-binding protein Era YP_002123788.1 1483108 R 552526 CDS YP_002123789.1 195978545 6762343 complement(1484140..1484541) 1 NC_011134.1 similar to ref|NP_606734.1| diacylglycerol kinase [Streptococcus pyogenes MGAS8232]; Recycling of diacylglycerol produced during the turnover of membrane phospholipids. May play a role in adaptability to environmental stress conditions such as acid tolerance, elevated temperatures and high osmolarity.; diacylglycerol kinase DgkA 1484541 dgkA 6762343 dgkA Streptococcus equi subsp. zooepidemicus MGCS10565 diacylglycerol kinase DgkA YP_002123789.1 1484140 R 552526 CDS YP_002123790.1 195978546 6762321 complement(1484522..1485019) 1 NC_011134.1 similar to gb|AAT86548.1| Hypothetical Metal-Binding Protein [Streptococcus pyogenes MGAS10394]; metalloprotease 1485019 6762321 Sez_1443 Streptococcus equi subsp. zooepidemicus MGCS10565 metalloprotease YP_002123790.1 1484522 R 552526 CDS YP_002123791.1 195978547 6761854 complement(1485364..1485990) 1 NC_011134.1 similar to ref|YP_001035552.1| Acetyltransferase, GNAT family, [Streptococcus sanguinis SK36]; Catalysis of the transfer of an acetyl group to a nitrogen atom on the acceptor molecule.; ribosomal-protein-S5p-alanine acetyltransferase 1485990 6761854 Sez_1444 Streptococcus equi subsp. zooepidemicus MGCS10565 ribosomal-protein-S5p-alanine acetyltransferase YP_002123791.1 1485364 R 552526 CDS YP_002123792.1 195978548 6761870 complement(1486045..1486620) 1 NC_011134.1 similar to ref|YP_059730.1| Uracil DNA glycosylase superfamily protein [Streptococcus pyogenes MGAS10394]; uracil-DNA glycosylase 1486620 6761870 Sez_1445 Streptococcus equi subsp. zooepidemicus MGCS10565 uracil-DNA glycosylase YP_002123792.1 1486045 R 552526 CDS YP_002123793.1 195978549 6762180 complement(1486664..1487767) 1 NC_011134.1 similar to ref|YP_596118.1| PhoH protein [Streptococcus pyogenes MGAS9429]; phosphate starvation-inducible protein PhoH 1487767 phoH 6762180 phoH Streptococcus equi subsp. zooepidemicus MGCS10565 phosphate starvation-inducible protein PhoH YP_002123793.1 1486664 R 552526 CDS YP_002123794.1 195978550 6761957 complement(1487870..1488085) 1 NC_011134.1 similar to ref|YP_138969.1| hypothetical protein stu0441 [Streptococcus thermophilus LMG 18311]; hypothetical protein 1488085 6761957 Sez_1447 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123794.1 1487870 R 552526 CDS YP_002123795.1 195978551 6762200 complement(1488082..1488591) 1 NC_011134.1 this stereospecific enzymes reduces the S isomer of methionine sulfoxide while MsrB reduces the R form; provides protection against oxidative stress; methionine sulfoxide reductase A 1488591 msrA 6762200 msrA Streptococcus equi subsp. zooepidemicus MGCS10565 methionine sulfoxide reductase A YP_002123795.1 1488082 R 552526 CDS YP_002123796.1 195978552 6761956 complement(1488929..1489786) 1 NC_011134.1 similar to ref|YP_819954.1| Predicted RNA-binding protein containing S1-like domain [Streptococcus thermophilus LMD-9]; S1 RNA binding domain 1489786 6761956 Sez_1449 Streptococcus equi subsp. zooepidemicus MGCS10565 S1 RNA binding domain YP_002123796.1 1488929 R 552526 CDS YP_002123797.1 195978553 6762196 complement(1489920..1490477) 1 NC_011134.1 Rrf; Frr; ribosome-recycling factor; release factor 4; RF4; recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G; A GTPase-dependent process results in release of 50S from 70S; inhibited by release factor RF-1; essential for viability; structurally similar to tRNAs; ribosome recycling factor 1490477 frr 6762196 frr Streptococcus equi subsp. zooepidemicus MGCS10565 ribosome recycling factor YP_002123797.1 1489920 R 552526 CDS YP_002123798.1 195978554 6761971 complement(1490514..1491242) 1 NC_011134.1 Catalyzes the phosphorylation of UMP to UDP; uridylate kinase 1491242 pyrH 6761971 pyrH Streptococcus equi subsp. zooepidemicus MGCS10565 uridylate kinase YP_002123798.1 1490514 R 552526 CDS YP_002123799.1 195978555 6762189 complement(1491899..1492579) 1 NC_011134.1 similar to ref|YP_001034501.1| Peptide ABC transporter, ATP-binding protein, [Streptococcus sanguinis SK36]; Part of the ABC transporter complex. Responsible for energy coupling to the transport system.; nickel or oligopeptide import ATP-binding protein 1492579 6762189 Sez_1452 Streptococcus equi subsp. zooepidemicus MGCS10565 nickel or oligopeptide import ATP-binding protein YP_002123799.1 1491899 R 552526 CDS YP_002123800.1 195978556 6761898 complement(1492566..1493366) 1 NC_011134.1 similar to ref|YP_001034500.1| Peptide ABC transporter, ATP-binding protein, [Streptococcus sanguinis SK36]; Part of the ABC transporter complex . Responsible for energy coupling to the transport system.; nickel or oligopeptide transport ATP-binding protein 1493366 6761898 Sez_1453 Streptococcus equi subsp. zooepidemicus MGCS10565 nickel or oligopeptide transport ATP-binding protein YP_002123800.1 1492566 R 552526 CDS YP_002123801.1 195978557 6762170 complement(1493342..1494148) 1 NC_011134.1 similar to ref|YP_001034500.1| Peptide ABC transporter, ATP-binding protein, [Streptococcus sanguinis SK36]; Membrane permease component of an ABC transporter complex.; nickel or oligopeptide transport system permease 1494148 6762170 Sez_1454 Streptococcus equi subsp. zooepidemicus MGCS10565 nickel or oligopeptide transport system permease YP_002123801.1 1493342 R 552526 CDS YP_002123802.1 195978558 6761967 complement(1494133..1495074) 1 NC_011134.1 similar to ref|ZP_00790162.1| peptide ABC transporter, permease [Streptococcus agalactiae 515]; Membrane permease component of an ABC transporter complex.; nickel or oligopeptide transport system permease 1495074 6761967 Sez_1455 Streptococcus equi subsp. zooepidemicus MGCS10565 nickel or oligopeptide transport system permease YP_002123802.1 1494133 R 552526 CDS YP_002123803.1 195978559 6762165 complement(1495152..1496774) 1 NC_011134.1 similar to ref|ZP_00788028.1| peptide ABC transporter, peptide-binding protein [Streptococcus agalactiae CJB111]; ABC transporter complex substrate-binding lipoprotein.; nickel or oligopeptide-binding periplasmic protein precursor 1496774 6762165 Sez_1456 Streptococcus equi subsp. zooepidemicus MGCS10565 nickel or oligopeptide-binding periplasmic protein precursor YP_002123803.1 1495152 R 552526 CDS YP_002123804.1 195978560 6761966 1497283..1499283 1 NC_011134.1 similar to gb|AAQ91575.1| collagen-like protein 3 [Streptococcus equi]; Possible fibronectin-binding adhesin, has a collagen-structural-motif domain composed of 97 Gly-Xaa-Yaa repeats.; hypothetical protein 1499283 sclZ.10 6761966 sclZ.10 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123804.1 1497283 D 552526 CDS YP_002123805.1 195978561 6761947 complement(1499810..1500499) 1 NC_011134.1 in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA; 50S ribosomal protein L1 1500499 rplA 6761947 rplA Streptococcus equi subsp. zooepidemicus MGCS10565 50S ribosomal protein L1 YP_002123805.1 1499810 R 552526 CDS YP_002123806.1 195978562 6762163 complement(1500605..1501030) 1 NC_011134.1 binds directly to 23S ribosomal RNA; 50S ribosomal protein L11 1501030 rplK 6762163 rplK Streptococcus equi subsp. zooepidemicus MGCS10565 50S ribosomal protein L11 YP_002123806.1 1500605 R 552526 CDS YP_002123807.1 195978563 6761946 complement(1501204..1502157) 1 NC_011134.1 similar to ref|YP_138591.1| IS1239 transposase [Streptococcus thermophilus LMG 18311]; transposase IS1239 1502157 6761946 Sez_1461 Streptococcus equi subsp. zooepidemicus MGCS10565 transposase IS1239 YP_002123807.1 1501204 R 552526 CDS YP_002123808.1 195978564 6762160 1502352..1503149 1 NC_011134.1 similar to ref|YP_598726.1| Transcriptional regulator, LacI family [Streptococcus pyogenes MGAS10270]; LacI family transcriptional regulator 1503149 6762160 Sez_1462 Streptococcus equi subsp. zooepidemicus MGCS10565 LacI family transcriptional regulator YP_002123808.1 1502352 D 552526 CDS YP_002123809.1 195978565 6761944 1503313..1503663 1 NC_011134.1 similar to ref|YP_281736.1| integral membrane protein [Streptococcus pyogenes MGAS5005]; hypothetical protein 1503663 6761944 Sez_1463 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123809.1 1503313 D 552526 CDS YP_002123810.1 195978566 6762140 complement(1503869..1506268) 1 NC_011134.1 similar to ref|YP_001129017.1| DNA translocase FtsK [Streptococcus pyogenes str. Manfredo]; DNA motor protein, which is both required to move DNA out of the region of the septum during cell division and for the septum formation. Tracks DNA in an ATP-dependent manner by generating positive supercoils in front of it and negative supercoils behind it.; DNA translocase FtsK 1506268 ftsK 6762140 ftsK Streptococcus equi subsp. zooepidemicus MGCS10565 DNA translocase FtsK YP_002123810.1 1503869 R 552526 CDS YP_002123811.1 195978567 6761943 1506388..1506561 1 NC_011134.1 hypothetical protein 1506561 6761943 Sez_1465 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123811.1 1506388 D 552526 CDS YP_002123812.1 195978568 6762130 1506648..1507454 1 NC_011134.1 similar to ref|NP_606719.1| cyclophilin-type protein [Streptococcus pyogenes MGAS8232]; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.; peptidyl-prolyl cis-trans isomerase cyclophilin-type 1507454 6762130 Sez_1466 Streptococcus equi subsp. zooepidemicus MGCS10565 peptidyl-prolyl cis-trans isomerase cyclophilin-type YP_002123812.1 1506648 D 552526 CDS YP_002123813.1 195978569 6761955 complement(1507610..1508443) 1 NC_011134.1 similar to ref|NP_606718.1| integral membrane protein MtsC [Streptococcus pyogenes MGAS8232]; Part of an ATP-driven transport system for a metal; this complex ly has affinity for Zn(2+), Fe(3+) and Cu(2+).; metal ABC transporter permease MtsC-like 1508443 mtsC 6761955 mtsC Streptococcus equi subsp. zooepidemicus MGCS10565 metal ABC transporter permease MtsC-like YP_002123813.1 1507610 R 552526 CDS YP_002123814.1 195978570 6762148 complement(1508444..1509169) 1 NC_011134.1 similar to ref|YP_279827.1| manganese transport system ATP-binding protein [Streptococcus pyogenes MGAS6180]; Part of an ATP-driven transport system for a metal; this complex ly has affinity for Zn(2+), Fe(3+) and Cu(2+).; metal ABC transporter ATP-binding protein MtsB-like 1509169 mtsB 6762148 mtsB Streptococcus equi subsp. zooepidemicus MGCS10565 metal ABC transporter ATP-binding protein MtsB-like YP_002123814.1 1508444 R 552526 CDS YP_002123815.1 195978571 6761953 complement(1509229..1510161) 1 NC_011134.1 similar to ref|YP_001129021.1| metal ABC transporter substrate-binding lipoprotein precursor [Streptococcus pyogenes str. Manfredo]; Part of an ATP-driven transport system for a metal; this protein ly has affinity for Zn(2+), Fe(3+) and Cu(2+).; metal ABC transporter substrate-binding lipoprotein precursor MtsA-like 1510161 mtsA 6761953 mtsA Streptococcus equi subsp. zooepidemicus MGCS10565 metal ABC transporter substrate-binding lipoprotein precursor MtsA-like YP_002123815.1 1509229 R 552526 CDS YP_002123816.1 195978572 6762125 1510307..1510954 1 NC_011134.1 similar to ref|YP_279825.1| iron-dependent repressor [Streptococcus pyogenes MGAS6180]; Iron-binding repressor of siderophore biosynthesis and iron uptake.; transcriptional regulator of metal ABC transporter MtsR-like 1510954 mtsR 6762125 mtsR Streptococcus equi subsp. zooepidemicus MGCS10565 transcriptional regulator of metal ABC transporter MtsR-like YP_002123816.1 1510307 D 552526 CDS YP_002123817.1 195978573 6761952 complement(1511004..1511705) 1 NC_011134.1 enables the cleavage of the glycosidic bond in both 5'-methylthioadenosine and S-adenosylhomocysteine; 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase 1511705 mtnN 6761952 mtnN Streptococcus equi subsp. zooepidemicus MGCS10565 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase YP_002123817.1 1511004 R 552526 CDS YP_002123818.1 195978574 6762138 complement(1511727..1511975) 1 NC_011134.1 similar to ref|YP_059706.1| Hypothetical membrane associated protein [Streptococcus pyogenes MGAS10394]; hypothetical protein 1511975 6762138 Sez_1472 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123818.1 1511727 R 552526 CDS YP_002123819.1 195978575 6761842 complement(1511975..1512529) 1 NC_011134.1 similar to ref|ZP_00365482.1| COG0494: NTP pyrophosphohydrolases including oxidative damage repair enzymes [Streptococcus pyogenes M49 591]; Acts on ADP-mannose and ADP-glucose as well as ADP- ribose. Prevents glycogen biosynthesis. The reaction catalyzed by this enzyme is a limiting step of the gluconeogenic process.; ADP-ribose pyrophosphatase 1512529 6761842 Sez_1473 Streptococcus equi subsp. zooepidemicus MGCS10565 ADP-ribose pyrophosphatase YP_002123819.1 1511975 R 552526 CDS YP_002123820.1 195978576 6762136 complement(1512560..1513942) 1 NC_011134.1 similar to gb|AAQ05206.1|AF468690_1 UDP-N-acetyl-glucosamine pyrophosphorylase [Streptococcus equi subsp. zooepidemicus]; Bifunctional Enzyme Responsible For The Acetylation Of Glc-N-1-P To Give Glcnac-1-P And The Synthesis Of UDP-GlcNAc.; bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase 1513942 gcaD 6762136 gcaD Streptococcus equi subsp. zooepidemicus MGCS10565 bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase YP_002123820.1 1512560 R 552526 CDS YP_002123821.1 195978577 6761950 1514151..1514279 1 NC_011134.1 hypothetical protein 1514279 6761950 Sez_1475 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123821.1 1514151 D 552526 CDS YP_002123822.1 195978578 6762112 complement(1514286..1515260) 1 NC_011134.1 similar to ref|YP_601856.1| NAD-dependent oxidoreductase [Streptococcus pyogenes MGAS10750]; NAD-dependent oxidoreductase 1515260 6762112 Sez_1476 Streptococcus equi subsp. zooepidemicus MGCS10565 NAD-dependent oxidoreductase YP_002123822.1 1514286 R 552526 CDS YP_002123823.1 195978579 6761937 complement(1515261..1515719) 1 NC_011134.1 similar to ref|ZP_00783841.1| conserved hypothetical protein [Streptococcus agalactiae H36B]; hypothetical protein 1515719 6761937 Sez_1477 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123823.1 1515261 R 552526 CDS YP_002123824.1 195978580 6762104 complement(1515918..1516616) 1 NC_011134.1 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis; 3-ketoacyl-ACP reductase 1516616 fabG 6762104 fabG Streptococcus equi subsp. zooepidemicus MGCS10565 3-ketoacyl-ACP reductase YP_002123824.1 1515918 R 552526 CDS YP_002123825.1 195978581 6761949 complement(1516609..1516845) 1 NC_011134.1 similar to ref|YP_001450753.1| hypothetical protein SGO_1474 [Streptococcus gordonii str. Challis substr. CH1]; hypothetical protein 1516845 6761949 Sez_1479 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123825.1 1516609 R 552526 CDS YP_002123826.1 195978582 6762124 1517351..1518067 1 NC_011134.1 similar to ref|YP_597968.1| hypothetical protein MGAS10270_Spy0359 [Streptococcus pyogenes MGAS10270]; hypothetical protein 1518067 6762124 Sez_1480 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123826.1 1517351 D 552526 CDS YP_002123827.1 195978583 6761915 complement(1518260..1518862) 1 NC_011134.1 similar to ref|ZP_00780519.1| cell surface protein, ErfK family [Streptococcus agalactiae 18RS21]; cell surface protein ErfK family 1518862 6761915 Sez_1481 Streptococcus equi subsp. zooepidemicus MGCS10565 cell surface protein ErfK family YP_002123827.1 1518260 R 552526 CDS YP_002123828.1 195978584 6762121 complement(1518954..1521605) 1 NC_011134.1 valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain; valyl-tRNA synthetase 1521605 valS 6762121 valS Streptococcus equi subsp. zooepidemicus MGCS10565 valyl-tRNA synthetase YP_002123828.1 1518954 R 552526 CDS YP_002123829.1 195978585 6761932 complement(1521618..1522181) 1 NC_011134.1 similar to ref|YP_597018.1| hypothetical protein MGAS9429_Spy1287 [Streptococcus pyogenes MGAS9429]; hypothetical protein 1522181 6761932 Sez_1483 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123829.1 1521618 R 552526 CDS YP_002123830.1 195978586 6762118 complement(1522381..1522965) 1 NC_011134.1 similar to ref|ZP_00788728.1| acetyltransferase, GNAT family [Streptococcus agalactiae CJB111]; GNAT family acetyltransferase 1522965 6762118 Sez_1484 Streptococcus equi subsp. zooepidemicus MGCS10565 GNAT family acetyltransferase YP_002123830.1 1522381 R 552526 CDS YP_002123831.1 195978587 6761945 complement(1522962..1523165) 1 NC_011134.1 hypothetical protein 1523165 6761945 Sez_1485 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123831.1 1522962 R 552526 CDS YP_002123832.1 195978588 6762115 complement(1523227..1523727) 1 NC_011134.1 similar to ref|YP_280764.1| hypothetical cytosolic protein [Streptococcus pyogenes MGAS6180]; hypothetical protein 1523727 6762115 Sez_1486 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123832.1 1523227 R 552526 CDS YP_002123833.1 195978589 6761911 complement(1523749..1524003) 1 NC_011134.1 similar to ref|NP_665082.1| hypothetical protein SpyM3_1278 [Streptococcus pyogenes MGAS315]; hypothetical protein 1524003 6761911 Sez_1487 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123833.1 1523749 R 552526 CDS YP_002123834.1 195978590 6761139 1524721..1525071 1 NC_011134.1 hypothetical protein 1525071 6761139 Sez_1488 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123834.1 1524721 D 552526 CDS YP_002123835.1 195978591 6761927 1525320..1526075 1 NC_011134.1 catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate; 3-deoxy-7-phosphoheptulonate synthase 1526075 aroA 6761927 aroA Streptococcus equi subsp. zooepidemicus MGCS10565 3-deoxy-7-phosphoheptulonate synthase YP_002123835.1 1525320 D 552526 CDS YP_002123836.1 195978592 6762084 1526110..1527216 1 NC_011134.1 catalyzes the formation of 3-dehydroquinate from 3-deoxy-arabino-heptulonate 7-phosphate; functions in aromatic amino acid biosynthesis; 3-dehydroquinate synthase 1527216 aroB 6762084 aroB Streptococcus equi subsp. zooepidemicus MGCS10565 3-dehydroquinate synthase YP_002123836.1 1526110 D 552526 CDS YP_002123837.1 195978593 6761940 1527366..1528052 1 NC_011134.1 similar to ref|YP_139291.1| ISSth1, transposase (orf1), IS3 family [Streptococcus thermophilus LMG 18311]; ISSth1, transposase orfA, IS3 family 1528052 6761940 Sez_1491 Streptococcus equi subsp. zooepidemicus MGCS10565 ISSth1, transposase orfA, IS3 family YP_002123837.1 1527366 D 552526 CDS YP_002123838.1 195978594 6762077 1528139..1528510 1 NC_011134.1 similar to ref|YP_139290.1| ISSth1, transposase (orf2), IS3 family [Streptococcus thermophilus LMG 18311]; ISSth1, transposase orfB, IS3 family 1528510 6762077 Sez_1492 Streptococcus equi subsp. zooepidemicus MGCS10565 ISSth1, transposase orfB, IS3 family YP_002123838.1 1528139 D 552526 CDS YP_002123839.1 195978595 6761941 1528494..1528937 1 NC_011134.1 similar to ref|YP_140248.1| ISSth1, transposase (orf2), IS3 family [Streptococcus thermophilus LMG 18311]; ISSth1, transposase orfC, IS3 family 1528937 6761941 Sez_1493 Streptococcus equi subsp. zooepidemicus MGCS10565 ISSth1, transposase orfC, IS3 family YP_002123839.1 1528494 D 552526 CDS YP_002123840.1 195978596 6762093 complement(1529234..1530007) 1 NC_011134.1 similar to ref|YP_329133.1| hypothetical protein SAK_0495 [Streptococcus agalactiae A909]; Catalysis of the reaction: uridine + phosphate = uracil + alpha-D-ribose 1-phosphate.; phosphorylase Pnp/Udp family 1530007 6762093 Sez_1494 Streptococcus equi subsp. zooepidemicus MGCS10565 phosphorylase Pnp/Udp family YP_002123840.1 1529234 R 552526 CDS YP_002123841.1 195978597 6761924 complement(1530133..1531017) 1 NC_011134.1 similar to ref|YP_280809.1| shikimate 5-dehydrogenase [Streptococcus pyogenes MGAS6180]; Aromatic amino acids biosynthesis; shikimate pathway; fourth step.; shikimate dehydrogenase 1531017 aroE 6761924 aroE Streptococcus equi subsp. zooepidemicus MGCS10565 shikimate dehydrogenase YP_002123841.1 1530133 R 552526 CDS YP_002123842.1 195978598 6762091 complement(1531168..1534611) 1 NC_011134.1 similar to ref|ZP_00366242.1| COG3250: Beta-galactosidase/beta-glucuronidase [Streptococcus pyogenes M49 591]; Catalysis of the hydrolysis of terminal, non-reducing beta-D-galactose residues in beta-D-galactosides.; beta-galactosidase LacZ 1534611 lacZ 6762091 lacZ Streptococcus equi subsp. zooepidemicus MGCS10565 beta-galactosidase LacZ YP_002123842.1 1531168 R 552526 CDS YP_002123843.1 195978599 6761938 complement(1534625..1536109) 1 NC_011134.1 similar to ref|YP_602908.1| Two-component response regulator yesN [Streptococcus pyogenes MGAS10750]; TCS response regulator YesN-like 1536109 yesN 6761938 yesN Streptococcus equi subsp. zooepidemicus MGCS10565 TCS response regulator YesN-like YP_002123843.1 1534625 R 552526 CDS YP_002123844.1 195978600 6762066 complement(1536109..1537803) 1 NC_011134.1 similar to ref|YP_602909.1| Two-component sensor kinase yesM [Streptococcus pyogenes MGAS10750]; TCS sensor kinase YesM-like 1537803 yesM 6762066 yesM Streptococcus equi subsp. zooepidemicus MGCS10565 TCS sensor kinase YesM-like YP_002123844.1 1536109 R 552526 CDS YP_002123845.1 195978601 6761933 complement(1537823..1538428) 1 NC_011134.1 similar to ref|YP_001128123.1| hypothetical protein SpyM50548 [Streptococcus pyogenes str. Manfredo]; hypothetical protein 1538428 6761933 Sez_1499 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123845.1 1537823 R 552526 CDS YP_002123846.1 195978602 6762063 complement(1538602..1538760) 1 NC_011134.1 hypothetical protein 1538760 6762063 Sez_1500 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123846.1 1538602 R 552526 CDS YP_002123847.1 195978603 6761923 complement(1538776..1540266) 1 NC_011134.1 similar to ref|NP_665093.1| sugar ABC transporter substrate binding protein [Streptococcus pyogenes MGAS315]; Probale ABC transporter substrate-binding lipoprotein.; hypothetical protein 1540266 6761923 Sez_1501 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123847.1 1538776 R 552526 CDS YP_002123848.1 195978604 6762079 complement(1540305..1541231) 1 NC_011134.1 similar to ref|NP_269653.1| sugar-binding transport protein [Streptococcus pyogenes M1 GAS]; Probably part of a binding-protein-dependent transport system. Probably responsible for the translocation of the substrate across the membrane.; multiple sugar ABC transporter permease MsmG 1541231 msmG 6762079 msmG Streptococcus equi subsp. zooepidemicus MGCS10565 multiple sugar ABC transporter permease MsmG YP_002123848.1 1540305 R 552526 CDS YP_002123849.1 195978605 6761905 complement(1541241..1542191) 1 NC_011134.1 similar to ref|YP_060646.1| Sugar transport system permease [Streptococcus pyogenes MGAS10394]; Probably part of a binding-protein-dependent transport system. Probably responsible for the translocation of the substrate across the membrane.; multiple sugar ABC transporter permease MsmF 1542191 msmF 6761905 msmF Streptococcus equi subsp. zooepidemicus MGCS10565 multiple sugar ABC transporter permease MsmF YP_002123849.1 1541241 R 552526 CDS YP_002123850.1 195978606 6762074 1542403..1543296 1 NC_011134.1 similar to ref|YP_282674.1| glucokinase [Streptococcus pyogenes MGAS5005]; Catalysis of the reaction: ATP + N-acyl-D-mannosamine = ADP + N-acyl-D-mannosamine 6-phosphate.; N-acetylmannosamine kinase 1543296 6762074 Sez_1504 Streptococcus equi subsp. zooepidemicus MGCS10565 N-acetylmannosamine kinase YP_002123850.1 1542403 D 552526 CDS YP_002123851.1 195978607 6761904 1543284..1545284 1 NC_011134.1 similar to ref|ZP_00602650.1| Alpha-1,2-mannosidase, [Enterococcus faecium DO]; alpha-1 2-mannosidase 1545284 6761904 Sez_1505 Streptococcus equi subsp. zooepidemicus MGCS10565 alpha-1 2-mannosidase YP_002123851.1 1543284 D 552526 CDS YP_002123852.1 195978608 6762058 complement(1545779..1547170) 1 NC_011134.1 similar to ref|YP_280819.1| beta-glucosidase [Streptococcus pyogenes MGAS6180]; Can hydrolyze salicin, cellobiose, and probably arbutin.; beta-glucosidase A BglA 1547170 bglA 6762058 bglA Streptococcus equi subsp. zooepidemicus MGCS10565 beta-glucosidase A BglA YP_002123852.1 1545779 R 552526 CDS YP_002123853.1 195978609 6761922 complement(1547197..1548891) 1 NC_011134.1 similar to ref|NP_665098.1| hyaluronidase [Streptococcus pyogenes MGAS315]; virulence factor which is likely to act on connective tissue during invasive infections, lacks a classical SrtA secretion signal sequence.; hyalurononglucosaminidase HylZ 1548891 hylZ 6761922 hylZ Streptococcus equi subsp. zooepidemicus MGCS10565 hyalurononglucosaminidase HylZ YP_002123853.1 1547197 R 552526 CDS YP_002123854.1 195978610 6762068 complement(1548906..1549964) 1 NC_011134.1 similar to ref|YP_001128116.1| GntR family regulatory protein [Streptococcus pyogenes str. Manfredo]; Transcriptional repressor like that of the arabinose utilization genes.; AraC family transcriptional regulator 1549964 6762068 Sez_1508 Streptococcus equi subsp. zooepidemicus MGCS10565 AraC family transcriptional regulator YP_002123854.1 1548906 R 552526 CDS YP_002123855.1 195978611 6761920 1550098..1551384 1 NC_011134.1 similar to ref|YP_060652.1| hypothetical protein M6_Spy1334 [Streptococcus pyogenes MGAS10394]; hypothetical protein 1551384 6761920 Sez_1509 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123855.1 1550098 D 552526 CDS YP_002123856.1 195978612 6762044 1551456..1554125 1 NC_011134.1 similar to ref|ZP_00365680.1| COG0383: Alpha-mannosidase [Streptococcus pyogenes M49 591]; Hydrolysis of terminal, non-reducing ?-D-mannose residues in ?-D-mannosides.; alpha-mannosidase 1554125 6762044 Sez_1510 Streptococcus equi subsp. zooepidemicus MGCS10565 alpha-mannosidase YP_002123856.1 1551456 D 552526 CDS YP_002123857.1 195978613 6761918 complement(1554309..1554917) 1 NC_011134.1 similar to ref|YP_001036161.1| ABC-type antimicrobial peptide transporter, ATPase component, [Streptococcus sanguinis SK36]; Part of the ABC transporter complex which could be involved in peptide resistance. Responsible for energy coupling to the transport system ().; ABC transporter ATP-binding protein 1554917 6761918 Sez_1511 Streptococcus equi subsp. zooepidemicus MGCS10565 ABC transporter ATP-binding protein YP_002123857.1 1554309 R 552526 CDS YP_002123858.1 195978614 6762041 complement(1554914..1556917) 1 NC_011134.1 similar to ref|YP_001036162.1| ABC-type antimicrobial peptide transporter, permease component, [Streptococcus sanguinis SK36]; ABC transporter permease 1556917 6762041 Sez_1512 Streptococcus equi subsp. zooepidemicus MGCS10565 ABC transporter permease YP_002123858.1 1554914 R 552526 CDS YP_002123859.1 195978615 6761893 1557581..1557820 1 NC_011134.1 hypothetical protein 1557820 6761893 Sez_1513 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123859.1 1557581 D 552526 CDS YP_002123860.1 195978616 6762039 complement(1557912..1558589) 1 NC_011134.1 similar to ref|YP_535527.1| Phosphinothricin N-acetyltransferase [Lactobacillus salivarius UCC118]; This enzyme is an effector of phosphinothricin tripeptide (PTT or bialaphos) resistance. Inactivates PTT by transfer of an acetyl group.; Phosphinothricin N-acetyltransferase 1558589 pat 6762039 pat Streptococcus equi subsp. zooepidemicus MGCS10565 Phosphinothricin N-acetyltransferase YP_002123860.1 1557912 R 552526 CDS YP_002123861.1 195978617 6761913 complement(1558753..1559166) 1 NC_011134.1 similar to ref|NP_722218.1| immunity protein, BLpL-like [Streptococcus mutans UA159]; bacteriocin immunity protein BLpL-Like 1559166 6761913 Sez_1515 Streptococcus equi subsp. zooepidemicus MGCS10565 bacteriocin immunity protein BLpL-Like YP_002123861.1 1558753 R 552526 CDS YP_002123862.1 195978618 6762037 complement(1559828..1560031) 1 NC_011134.1 similar to ref|ZP_01821308.1| BlpN protein [Streptococcus pneumoniae SP6-BS73]; bacteriocin BlpN-like 1560031 6762037 Sez_1516 Streptococcus equi subsp. zooepidemicus MGCS10565 bacteriocin BlpN-like YP_002123862.1 1559828 R 552526 CDS YP_002123863.1 195978619 6761889 complement(1560048..1560302) 1 NC_011134.1 similar to ref|ZP_01821307.1| bacteriocin BlpM [Streptococcus pneumoniae SP6-BS73]; bacteriocin BlpM-like 1560302 6761889 Sez_1517 Streptococcus equi subsp. zooepidemicus MGCS10565 bacteriocin BlpM-like YP_002123863.1 1560048 R 552526 CDS YP_002123864.1 195978620 6762034 complement(1560456..1560752) 1 NC_011134.1 similar to gb|ABQ23940.1| ubericin A immunity protein [Streptococcus uberis]; immunity protein 1560752 6762034 Sez_1518 Streptococcus equi subsp. zooepidemicus MGCS10565 immunity protein YP_002123864.1 1560456 R 552526 CDS YP_002123865.1 195978621 6761912 1561281..1561796 1 NC_011134.1 similar to ref|NP_688076.1| IS861, transposase OrfA [Streptococcus agalactiae 2603V/R]; transposase IS861 orfA 1561796 6761912 Sez_1519 Streptococcus equi subsp. zooepidemicus MGCS10565 transposase IS861 orfA YP_002123865.1 1561281 D 552526 CDS YP_002123866.1 195978622 6762031 1561793..1562629 1 NC_011134.1 similar to ref|NP_720882.1| transposase, ISSmu1 [Streptococcus mutans UA159]; transposase IS861 orfB 1562629 6762031 Sez_1520 Streptococcus equi subsp. zooepidemicus MGCS10565 transposase IS861 orfB YP_002123866.1 1561793 D 552526 CDS YP_002123867.1 195978623 6761910 complement(1563014..1563310) 1 NC_011134.1 similar to dbj|BAF37251.1| hypothetical protein [Streptococcus bovis]; hypothetical protein 1563310 6761910 Sez_1521 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123867.1 1563014 R 552526 CDS YP_002123868.1 195978624 6762047 complement(1563317..1563550) 1 NC_011134.1 similar to gb|AAG29818.1|AF298196_1 bovicin 255 peptide precursor [Streptococcus sp. LRC 0255]; bacteriocin-like peptide 1563550 6762047 Sez_1522 Streptococcus equi subsp. zooepidemicus MGCS10565 bacteriocin-like peptide YP_002123868.1 1563317 R 552526 CDS YP_002123869.1 195978625 6761909 1563824..1565980 1 NC_011134.1 similar to ref|YP_601902.1| Bacteriocin processing peptidase / Bacteriocin export ABC transporter [Streptococcus pyogenes MGAS10750]; Possibly involved in transport of competence-stimulating peptide (CSP).; transport/processing ATP-binding protein ComA-like 1565980 6761909 Sez_1523 Streptococcus equi subsp. zooepidemicus MGCS10565 transport/processing ATP-binding protein ComA-like YP_002123869.1 1563824 D 552526 CDS YP_002123870.1 195978626 6762006 1565949..1567349 1 NC_011134.1 similar to ref|ZP_01821305.1| BlpC ABC transporter [Streptococcus pneumoniae SP6-BS73]; peptide ABC transporter 1567349 6762006 Sez_1524 Streptococcus equi subsp. zooepidemicus MGCS10565 peptide ABC transporter YP_002123870.1 1565949 D 552526 CDS YP_002123871.1 195978627 6761907 1567449..1567583 1 NC_011134.1 similar to emb|CAC10163.1| bacteriocin-like peptide, double glycin clevage motif [Streptococcus pneumoniae]; bacteriocin peptide BlpC-like 1567583 6761907 Sez_1525 Streptococcus equi subsp. zooepidemicus MGCS10565 bacteriocin peptide BlpC-like YP_002123871.1 1567449 D 552526 CDS YP_002123872.1 195978628 6762030 complement(1567702..1569036) 1 NC_011134.1 similar to ref|ZP_00788187.1| sensor histidine kinase BlpH, [Streptococcus agalactiae CJB111]; TCS sensor kinase 1569036 6762030 Sez_1526 Streptococcus equi subsp. zooepidemicus MGCS10565 TCS sensor kinase YP_002123872.1 1567702 R 552526 CDS YP_002123873.1 195978629 6761906 complement(1569036..1569785) 1 NC_011134.1 similar to ref|NP_688944.1| response regulator [Streptococcus agalactiae 2603V/R]; TCS response regulator FasA/ComE/BlpR-like 1569785 6761906 Sez_1527 Streptococcus equi subsp. zooepidemicus MGCS10565 TCS response regulator FasA/ComE/BlpR-like YP_002123873.1 1569036 R 552526 CDS YP_002123874.1 195978630 6762016 complement(1570082..1571035) 1 NC_011134.1 similar to ref|YP_138591.1| IS1239 transposase [Streptococcus thermophilus LMG 18311]; transposase IS1239 1571035 6762016 Sez_1528 Streptococcus equi subsp. zooepidemicus MGCS10565 transposase IS1239 YP_002123874.1 1570082 R 552526 CDS YP_002123875.1 195978631 6761903 complement(1571510..1571713) 1 NC_011134.1 similar to gb|AAB91456.1| enhancer peptide for thermophilin 13 precursor; ThmB [Streptococcus thermophilus]; TmhB-like bacteriocin enhancer peptide 1571713 6761903 Sez_1529 Streptococcus equi subsp. zooepidemicus MGCS10565 TmhB-like bacteriocin enhancer peptide YP_002123875.1 1571510 R 552526 CDS YP_002123876.1 195978632 6762009 complement(1571730..1571987) 1 NC_011134.1 similar to gb|AAB91455.1| amphipathic pore-forming peptide precursor; ThmA [Streptococcus thermophilus]; ThmA-like bacteriocin 1571987 6762009 Sez_1530 Streptococcus equi subsp. zooepidemicus MGCS10565 ThmA-like bacteriocin YP_002123876.1 1571730 R 552526 CDS YP_002123877.1 195978633 6761901 complement(1572308..1573675) 1 NC_011134.1 similar to ref|YP_599044.1| tRNA (Uracil-5-) -methyltransferase [Streptococcus pyogenes MGAS10270]; Could Be A 23s rRNA (Uracil-5-)-Methyltransferase.; RNA methyltransferase TrmA family 1573675 6761901 Sez_1531 Streptococcus equi subsp. zooepidemicus MGCS10565 RNA methyltransferase TrmA family YP_002123877.1 1572308 R 552526 CDS YP_002123878.1 195978634 6762025 complement(1573672..1574640) 1 NC_011134.1 similar to ref|ZP_00144239.1| hypothetical protein [Fusobacterium nucleatum subsp. vincentii ATCC 49256]; hypothetical protein 1574640 6762025 Sez_1532 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123878.1 1573672 R 552526 CDS YP_002123879.1 195978635 6761873 1575390..1575905 1 NC_011134.1 similar to ref|YP_602677.1| Transposase [Streptococcus pyogenes MGAS10750]; transposase IS861 orfA 1575905 6761873 Sez_1533 Streptococcus equi subsp. zooepidemicus MGCS10565 transposase IS861 orfA YP_002123879.1 1575390 D 552526 CDS YP_002123880.1 195978636 6762018 1575929..1576732 1 NC_011134.1 similar to ref|NP_268574.1| transposase, IS861 [Streptococcus pyogenes M1 GAS]; transposase IS861 orfB 1576732 6762018 Sez_1534 Streptococcus equi subsp. zooepidemicus MGCS10565 transposase IS861 orfB YP_002123880.1 1575929 D 552526 CDS YP_002123881.1 195978637 6761890 1576902..1577162 1 NC_011134.1 similar to ref|ZP_01963858.1| hypothetical protein RUMOBE_01582 [Ruminococcus obeum ATCC 29174]; hypothetical protein 1577162 6761890 Sez_1535 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123881.1 1576902 D 552526 CDS YP_002123882.1 195978638 6762014 1577231..1579663 1 NC_011134.1 similar to ref|ZP_00372061.1| adenine/cytosine DNA methyltransferase [Campylobacter upsaliensis RM3195]; adenine/cytosine DNA methyltransferase 1579663 6762014 Sez_1536 Streptococcus equi subsp. zooepidemicus MGCS10565 adenine/cytosine DNA methyltransferase YP_002123882.1 1577231 D 552526 CDS YP_002123883.1 195978639 6761891 1579680..1580186 1 NC_011134.1 similar to ref|ZP_02436627.1| hypothetical protein BACSTE_02895 [Bacteroides stercoris ATCC 43183]; hypothetical protein 1580186 6761891 Sez_1537 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123883.1 1579680 D 552526 CDS YP_002123884.1 195978640 6762008 1580183..1581436 1 NC_011134.1 similar to emb|CAI94870.1| Hin4II restriction endonuclease [Haemophilus influenzae]; hypothetical protein 1581436 6762008 Sez_1538 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123884.1 1580183 D 552526 CDS YP_002123885.1 195978641 6761809 1581446..1582375 1 NC_011134.1 similar to ref|YP_001035816.1| hypothetical protein SSA_1888 [Streptococcus sanguinis SK36]; hypothetical protein 1582375 6761809 Sez_1539 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123885.1 1581446 D 552526 CDS YP_002123886.1 195978642 6761990 1582376..1584436 1 NC_011134.1 similar to ref|ZP_02063370.1| hypothetical protein BACOVA_00315 [Bacteroides ovatus ATCC 8483]; hypothetical protein 1584436 6761990 Sez_1540 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123886.1 1582376 D 552526 CDS YP_002123887.1 195978643 6761865 1584673..1585449 1 NC_011134.1 binds RecA and inhibits RecA-mediated DNA strand exchange and ATP hydrolysis and coprotease activities; recombination regulator RecX 1585449 recX 6761865 recX Streptococcus equi subsp. zooepidemicus MGCS10565 recombination regulator RecX YP_002123887.1 1584673 D 552526 CDS YP_002123888.1 195978644 6761987 1585682..1586215 1 NC_011134.1 similar to ref|ZP_00365988.1| COG3557: Uncharacterized domain/protein associated with RNAses G and E [Streptococcus pyogenes M49 591]; hypothetical protein 1586215 6761987 Sez_1542 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123888.1 1585682 D 552526 CDS YP_002123889.1 195978645 6761887 1586465..1586776 1 NC_011134.1 similar to ref|NP_722103.1| hypothetical protein SMU.1782 [Streptococcus mutans UA159]; hypothetical protein 1586776 6761887 Sez_1543 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123889.1 1586465 D 552526 CDS YP_002123890.1 195978646 6761982 1587436..1587804 1 NC_011134.1 similar to ref|ZP_00875692.1| Transposase, IS204/IS1001/IS1096/IS1165 [Streptococcus suis 89/1591]; transposase, ISL3 family 1587804 6761982 Sez_1544 Streptococcus equi subsp. zooepidemicus MGCS10565 transposase, ISL3 family YP_002123890.1 1587436 D 552526 CDS YP_002123891.1 195978647 6761173 complement(1593817..1594365) 1 NC_011134.1 similar to ref|NP_665162.1| ribosomal subunit interface protein [Streptococcus pyogenes MGAS315]; Probably Modulates The Activity Of Sigma(54) (RpoN).; ribosomal subunit interface protein 1594365 PSrp-1 6761173 PSrp-1 Streptococcus equi subsp. zooepidemicus MGCS10565 ribosomal subunit interface protein YP_002123891.1 1593817 R 552526 CDS YP_002123892.1 195978648 6761996 complement(1594441..1595022) 1 NC_011134.1 similar to ref|YP_060690.1| ComF operon protein 3 [Streptococcus pyogenes MGAS10394]; Involved in transformation (competence for DNA uptake).; competence protein ComF 1595022 comFC 6761996 comFC Streptococcus equi subsp. zooepidemicus MGCS10565 competence protein ComF YP_002123892.1 1594441 R 552526 CDS YP_002123893.1 195978649 6761883 complement(1595081..1596403) 1 NC_011134.1 similar to ref|YP_599052.1| COMF operon protein 1 [Streptococcus pyogenes MGAS10270]; Involved in transformation (competence for DNA uptake). Required for DNA uptake but not for binding. May provide the driving force for transport of DNA through an aqueous channel.; competence protein ComF 1596403 comFA 6761883 comFA Streptococcus equi subsp. zooepidemicus MGCS10565 competence protein ComF YP_002123893.1 1595081 R 552526 CDS YP_002123894.1 195978650 6761973 1596459..1597100 1 NC_011134.1 similar to ref|NP_665166.1| hypothetical protein SpyM3_1362 [Streptococcus pyogenes MGAS315]; hypothetical protein 1597100 6761973 Sez_1548 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123894.1 1596459 D 552526 CDS YP_002123895.1 195978651 6761861 1597222..1598148 1 NC_011134.1 similar to ref|ZP_00875431.1| Cysteine synthase K/M:Cysteine synthase A [Streptococcus suis 89/1591]; Cysteine biosynthesis, Catalysis of the reaction: O3-acetyl-L-serine + H2S = L-cysteine + acetate.; cysteine synthase 1598148 cysK 6761861 cysK Streptococcus equi subsp. zooepidemicus MGCS10565 cysteine synthase YP_002123895.1 1597222 D 552526 CDS YP_002123896.1 195978652 6761986 1598417..1598554 1 NC_011134.1 hypothetical protein 1598554 6761986 Sez_1550 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123896.1 1598417 D 552526 CDS YP_002123897.1 195978653 6761881 complement(1598535..1598897) 1 NC_011134.1 similar to gb|AAN58235.1|AE014894_12 polyribonucleotide nucleotidyltransferase (general stress protein 13) [Streptococcus mutans UA159]; Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno purine-rich sequence.; hypothetical protein 1598897 6761881 Sez_1551 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123897.1 1598535 R 552526 CDS YP_002123898.1 195978654 6761984 complement(1598897..1600309) 1 NC_011134.1 similar to ref|YP_060695.1| Peptidyl-prolyl cis-trans isomerase [Streptococcus pyogenes MGAS10394]; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.; peptidyl-prolyl cis-trans isomerase-like 1600309 6761984 Sez_1552 Streptococcus equi subsp. zooepidemicus MGCS10565 peptidyl-prolyl cis-trans isomerase-like YP_002123898.1 1598897 R 552526 CDS YP_002123899.1 195978655 6761880 complement(1600331..1600924) 1 NC_011134.1 similar to ref|YP_060696.1| Two-component response regulator yvqC [Streptococcus pyogenes MGAS10394]; TCS response regulator YvqC-like 1600924 yvqC 6761880 yvqC Streptococcus equi subsp. zooepidemicus MGCS10565 TCS response regulator YvqC-like YP_002123899.1 1600331 R 552526 CDS YP_002123900.1 195978656 6761448 complement(1600965..1601969) 1 NC_011134.1 similar to ref|NP_607684.1| two-component sensor histidine kinase [Streptococcus pyogenes MGAS8232]; TCS sensor kinase YvqE-like 1601969 yvqE 6761448 yvqE Streptococcus equi subsp. zooepidemicus MGCS10565 TCS sensor kinase YvqE-like YP_002123900.1 1600965 R 552526 CDS YP_002123901.1 195978657 6761482 complement(1601966..1602622) 1 NC_011134.1 similar to ref|YP_001128043.1| hypothetical protein SpyM50457 [Streptococcus pyogenes str. Manfredo]; hypothetical transporter protein YvqF-like 1602622 yvqF 6761482 yvqF Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical transporter protein YvqF-like YP_002123901.1 1601966 R 552526 CDS YP_002123902.1 195978658 6761481 complement(1602791..1604686) 1 NC_011134.1 similar to ref|YP_599060.1| Serine/threonine protein kinase [Streptococcus pyogenes MGAS10270]; Regulation of stationary phase.; serine/threonine protein kinase PrkC 1604686 prkC 6761481 prkC Streptococcus equi subsp. zooepidemicus MGCS10565 serine/threonine protein kinase PrkC YP_002123902.1 1602791 R 552526 CDS YP_002123903.1 195978659 6761480 complement(1604683..1605423) 1 NC_011134.1 similar to ref|NP_269676.1| phosphoprotein phosphatase [Streptococcus pyogenes M1 GAS]; Regulation of stationary phase.; serine/threonine phosphatase PrpC 1605423 prpC 6761480 prpC Streptococcus equi subsp. zooepidemicus MGCS10565 serine/threonine phosphatase PrpC YP_002123903.1 1604683 R 552526 CDS YP_002123904.1 195978660 6761474 complement(1605461..1606789) 1 NC_011134.1 similar to ref|YP_060701.1| 16S rRNA m(5)C 967 methyltransferase [Streptococcus pyogenes MGAS10394]; 16S rRNA m(5)C 967 methyltransferase RsmB 1606789 rsmB 6761474 rsmB Streptococcus equi subsp. zooepidemicus MGCS10565 16S rRNA m(5)C 967 methyltransferase RsmB YP_002123904.1 1605461 R 552526 CDS YP_002123905.1 195978661 6761449 complement(1606773..1607690) 1 NC_011134.1 modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet) which is important in translation initiation; inactivation of this gene in Escherichia coli severely impairs growth; methionyl-tRNA formyltransferase 1607690 fmt 6761449 fmt Streptococcus equi subsp. zooepidemicus MGCS10565 methionyl-tRNA formyltransferase YP_002123905.1 1606773 R 552526 CDS YP_002123906.1 195978662 6761355 complement(1607775..1610159) 1 NC_011134.1 binding of PriA to forked DNA starts the assembly of the primosome, also possesses 3'-5' helicase activity; primosome assembly protein PriA 1610159 priA 6761355 priA Streptococcus equi subsp. zooepidemicus MGCS10565 primosome assembly protein PriA YP_002123906.1 1607775 R 552526 CDS YP_002123907.1 195978663 6761470 complement(1610223..1610540) 1 NC_011134.1 Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits; DNA-directed RNA polymerase subunit omega 1610540 rpoZ 6761470 rpoZ Streptococcus equi subsp. zooepidemicus MGCS10565 DNA-directed RNA polymerase subunit omega YP_002123907.1 1610223 R 552526 CDS YP_002123908.1 195978664 6761468 complement(1610565..1611191) 1 NC_011134.1 Essential for recycling GMP and indirectly, cGMP; guanylate kinase 1611191 gmk 6761468 gmk Streptococcus equi subsp. zooepidemicus MGCS10565 guanylate kinase YP_002123908.1 1610565 R 552526 CDS YP_002123909.1 195978665 6761467 complement(1611202..1611339) 1 NC_011134.1 hypothetical protein 1611339 6761467 Sez_1563 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123909.1 1611202 R 552526 CDS YP_002123910.1 195978666 6761444 complement(1611355..1612965) 1 NC_011134.1 similar to ref|NP_269682.1| hypothetical protein SPy_1633 [Streptococcus pyogenes M1 GAS]; hypothetical protein 1612965 6761444 Sez_1564 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123910.1 1611355 R 552526 CDS YP_002123911.1 195978667 6761465 1613077..1613607 1 NC_011134.1 catalyzes the hydrolysis of S-ribosylhomocysteine to homocysteine and autoinducer-2; S-ribosylhomocysteinase 1613607 luxS 6761465 luxS Streptococcus equi subsp. zooepidemicus MGCS10565 S-ribosylhomocysteinase YP_002123911.1 1613077 D 552526 CDS YP_002123912.1 195978668 6761437 complement(1613754..1615205) 1 NC_011134.1 similar to ref|NP_665189.1| hypothetical protein SpyM3_1385 [Streptococcus pyogenes MGAS315]; hypothetical protein 1615205 6761437 Sez_1566 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123912.1 1613754 R 552526 CDS YP_002123913.1 195978669 6761458 complement(1615219..1616373) 1 NC_011134.1 similar to ref|YP_001128027.1| RNA methylase family protein [Streptococcus pyogenes str. Manfredo]; methyltransferase; N6-adenine-specific DNA methylase 1616373 6761458 Sez_1567 Streptococcus equi subsp. zooepidemicus MGCS10565 methyltransferase; N6-adenine-specific DNA methylase YP_002123913.1 1615219 R 552526 CDS YP_002123914.1 195978670 6761434 complement(1616819..1617142) 1 NC_011134.1 similar to ref|YP_280858.1| cell division initiation protein DivIVA [Streptococcus pyogenes MGAS6180]; cell division initiation protein DivIVA 1617142 6761434 Sez_1568 Streptococcus equi subsp. zooepidemicus MGCS10565 cell division initiation protein DivIVA YP_002123914.1 1616819 R 552526 CDS YP_002123915.1 195978671 6761456 complement(1617264..1617779) 1 NC_011134.1 similar to ref|YP_599079.1| hypothetical cytosolic protein [Streptococcus pyogenes MGAS10270]; hypothetical protein 1617779 6761456 Sez_1569 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123915.1 1617264 R 552526 CDS YP_002123916.1 195978672 6761429 1617855..1618463 1 NC_011134.1 RecU; functions in homologous recombination, DNA repair, and chromosome segregation; binds preferentially to three- and four-stranded DNA intermediates; introduces specific nick sites in four-stranded DNA substrates; functions similarly to Escherichia coli RuvC; Holliday junction-specific endonuclease 1618463 recU 6761429 recU Streptococcus equi subsp. zooepidemicus MGCS10565 Holliday junction-specific endonuclease YP_002123916.1 1617855 D 552526 CDS YP_002123917.1 195978673 6761453 1618525..1620615 1 NC_011134.1 similar to ref|YP_280861.1| multimodular transpeptidase-transglycosylase [Streptococcus pyogenes MGAS6180]; Peptidoglycan synthesis, nascent glycan strand synthesis and cross-linking.; multimodular transpeptidase-transglycosylase; penicillin-binding protein 1A PonA 1620615 ponA 6761453 ponA Streptococcus equi subsp. zooepidemicus MGCS10565 multimodular transpeptidase-transglycosylase; penicillin-binding protein 1A PonA YP_002123917.1 1618525 D 552526 CDS YP_002123918.1 195978674 6761451 complement(1621004..1622341) 1 NC_011134.1 similar to ref|YP_280862.1| aminopeptidase C [Streptococcus pyogenes MGAS6180]; Catalysis of the inactivation of bleomycin B2 (a cytotoxic glycometallopeptide) by hydrolysis of a peptide bond of beta-aminoalanine, but also shows general aminopeptidase activity. The specificity varies somewhat with source, but amino acid arylamides of Met, Leu and Ala are preferred.; aminopeptidase 1622341 pepC 6761451 pepC Streptococcus equi subsp. zooepidemicus MGCS10565 aminopeptidase YP_002123918.1 1621004 R 552526 CDS YP_002123919.1 195978675 6761446 complement(1623038..1623862) 1 NC_011134.1 catalyzes the formation of nicotinamide adenine dinucleotide (NAD) from nicotinic acid adenine dinucleotide (NAAD) using either ammonia or glutamine as the amide donor and ATP; ammonia-utilizing enzymes include the ones from Bacillus and Escherichia coli while glutamine-utilizing enzymes include the Mycobacterial one; forms homodimers; NAD synthetase 1623862 nadE 6761446 nadE Streptococcus equi subsp. zooepidemicus MGCS10565 NAD synthetase YP_002123919.1 1623038 R 552526 CDS YP_002123920.1 195978676 6761445 complement(1623859..1625319) 1 NC_011134.1 catalyzes the formation of 5-phospho-alpha-D-ribose 1-diphosphate and nicotinate from nicotinate D-ribonucleotide and diphosphate; nicotinate phosphoribosyltransferase 1625319 6761445 Sez_1574 Streptococcus equi subsp. zooepidemicus MGCS10565 nicotinate phosphoribosyltransferase YP_002123920.1 1623859 R 552526 CDS YP_002123921.1 195978677 6761421 complement(1625298..1625447) 1 NC_011134.1 hypothetical protein 1625447 6761421 Sez_1575 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123921.1 1625298 R 552526 CDS YP_002123922.1 195978678 6761439 complement(1625595..1627001) 1 NC_011134.1 similar to ref|YP_060723.1| Amino acid permease [Streptococcus pyogenes MGAS10394]; amino-acid or metabolite transport protein.; amino acid permease 1627001 6761439 Sez_1576 Streptococcus equi subsp. zooepidemicus MGCS10565 amino acid permease YP_002123922.1 1625595 R 552526 CDS YP_002123923.1 195978679 6761349 complement(1627108..1628025) 1 NC_011134.1 similar to ref|YP_599086.1| Thioredoxin reductase [Streptococcus pyogenes MGAS10270]; Catalysis of the reaction: thioredoxin + NADP+ = thioredoxin disulfide + NADPH + H+.; thioredoxin reductase 1628025 trxB 6761349 trxB Streptococcus equi subsp. zooepidemicus MGCS10565 thioredoxin reductase YP_002123923.1 1627108 R 552526 CDS YP_002123924.1 195978680 6761413 complement(1628085..1628312) 1 NC_011134.1 similar to ref|NP_269700.1| hypothetical protein SPy_1656 [Streptococcus pyogenes M1 GAS]; hypothetical protein 1628312 6761413 Sez_1578 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123924.1 1628085 R 552526 CDS YP_002123925.1 195978681 6761412 complement(1628422..1629165) 1 NC_011134.1 similar to ref|YP_597089.1| amino acid transport ATP-binding protein [Streptococcus pyogenes MGAS9429]; Probably part of a binding-protein-dependent transport system for an amino acid. Probably responsible for energy coupling to the transport system.; aspartate/glutamate ABC transporter ATP-binding protein 1629165 6761412 Sez_1579 Streptococcus equi subsp. zooepidemicus MGCS10565 aspartate/glutamate ABC transporter ATP-binding protein YP_002123925.1 1628422 R 552526 CDS YP_002123926.1 195978682 6761433 complement(1629165..1629968) 1 NC_011134.1 similar to ref|YP_001128015.1| ABC transporter permease [Streptococcus pyogenes str. Manfredo]; Probably part of a binding-protein-dependent transport system for an amino acid. Probably responsible for the translocation of the substrate across the membrane.; amino-acid ABC transporter permease 1629968 6761433 Sez_1580 Streptococcus equi subsp. zooepidemicus MGCS10565 amino-acid ABC transporter permease YP_002123926.1 1629165 R 552526 CDS YP_002123927.1 195978683 6761403 1630133..1630282 1 NC_011134.1 hypothetical protein 1630282 6761403 Sez_1581 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123927.1 1630133 D 552526 CDS YP_002123928.1 195978684 6761402 complement(1630316..1631143) 1 NC_011134.1 similar to ref|NP_720902.1| ABC transporter, amino acid binding protein [Streptococcus mutans UA159]; Probably part of the substrate-binding-protein-dependent transport system for an amino acid.; amino-acid ABC transporter extracellular-binding protein precursor 1631143 6761402 Sez_1582 Streptococcus equi subsp. zooepidemicus MGCS10565 amino-acid ABC transporter extracellular-binding protein precursor YP_002123928.1 1630316 R 552526 CDS YP_002123929.1 195978685 6761398 1631648..1632103 1 NC_011134.1 hypothetical protein 1632103 6761398 Sez_1583 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123929.1 1631648 D 552526 CDS YP_002123930.1 195978686 6761400 complement(1632744..1634087) 1 NC_011134.1 similar to ref|YP_060728.1| ATP-dependent RNA helicase [Streptococcus pyogenes MGAS10394]; Has A Helix-Destabilizing Activity. Plays A Key Role In Optimal Cell Growth At Low Temperature And Is Required For Normal Cell Division. Suppressor Of A Mutant Defective In Rpsb Gene For Ribosomal Protein S2.; ATP-dependent RNA helicase DEAD/DEAH box family 1634087 6761400 Sez_1584 Streptococcus equi subsp. zooepidemicus MGCS10565 ATP-dependent RNA helicase DEAD/DEAH box family YP_002123930.1 1632744 R 552526 CDS YP_002123931.1 195978687 6761425 complement(1634170..1635177) 1 NC_011134.1 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; phospho-N-acetylmuramoyl-pentapeptide- transferase 1635177 mraY 6761425 mraY Streptococcus equi subsp. zooepidemicus MGCS10565 phospho-N-acetylmuramoyl-pentapeptide- transferase YP_002123931.1 1634170 R 552526 CDS YP_002123932.1 195978688 6761424 complement(1635179..1637434) 1 NC_011134.1 similar to ref|YP_060731.1| Division specific D,D-transpeptidase [Streptococcus pyogenes MGAS10394]; Peptidoglycan synthesis, Catalysis of the reaction: [GlcNAc-(1, 4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)](n)- diphosphoundecaprenol + GlcNAc-(1, 4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)- diphosphoundecaprenol = [GlcNAc-(1, 4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)](n+1)- diphosphoundecaprenol + UDP diphosphate.; cell division protein FtsI 1637434 ftsI 6761424 ftsI Streptococcus equi subsp. zooepidemicus MGCS10565 cell division protein FtsI YP_002123932.1 1635179 R 552526 CDS YP_002123933.1 195978689 6761426 complement(1637438..1637761) 1 NC_011134.1 similar to ref|ZP_00365943.1| COG4839: Protein required for the initiation of cell division [Streptococcus pyogenes M49 591]; Involved in initiation of cell division.; FtsL protein 1637761 ftsL 6761426 ftsL Streptococcus equi subsp. zooepidemicus MGCS10565 FtsL protein YP_002123933.1 1637438 R 552526 CDS YP_002123934.1 195978690 6761396 complement(1637765..1638715) 1 NC_011134.1 similar to sp|Q5XAL3|MRAW_STRP6 S-adenosyl-L-methionine-dependent methyltransferase mraW; S-adenosyl-methyltransferase MraW 1638715 mraW 6761396 mraW Streptococcus equi subsp. zooepidemicus MGCS10565 S-adenosyl-methyltransferase MraW YP_002123934.1 1637765 R 552526 CDS YP_002123935.1 195978691 6761420 complement(1638818..1639234) 1 NC_011134.1 similar to ref|NP_607720.1| hypothetical protein spyM18_1678 [Streptococcus pyogenes MGAS8232]; hypothetical protein 1639234 6761420 Sez_1589 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123935.1 1638818 R 552526 CDS YP_002123936.1 195978692 6761419 complement(1639254..1640504) 1 NC_011134.1 Catalyzes the phosphorylation of L-glutamate during the proline biosynthesis pathway; gamma-glutamyl phosphate reductase 1640504 proA 6761419 proA Streptococcus equi subsp. zooepidemicus MGCS10565 gamma-glutamyl phosphate reductase YP_002123936.1 1639254 R 552526 CDS YP_002123937.1 195978693 6761417 complement(1640501..1641319) 1 NC_011134.1 catalyzes the formation of glutamate 5-phosphate from glutamate in proline biosynthesis; gamma-glutamyl kinase 1641319 proB 6761417 proB Streptococcus equi subsp. zooepidemicus MGCS10565 gamma-glutamyl kinase YP_002123937.1 1640501 R 552526 CDS YP_002123938.1 195978694 6761410 1641930..1643048 1 NC_011134.1 similar to ref|YP_001198821.1| hypothetical protein SSU05_1455 [Streptococcus suis 05ZYH33]; hypothetical protein 1643048 6761410 Sez_1592 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123938.1 1641930 D 552526 CDS YP_002123939.1 195978695 6761409 complement(1643214..1643384) 1 NC_011134.1 hypothetical protein 1643384 6761409 Sez_1593 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123939.1 1643214 R 552526 CDS YP_002123940.1 195978696 6761384 complement(1643567..1645195) 1 NC_011134.1 similar to ref|YP_282735.1| ABC transporter permease [Streptococcus pyogenes MGAS5005]; ABC transporter permease 1645195 6761384 Sez_1594 Streptococcus equi subsp. zooepidemicus MGCS10565 ABC transporter permease YP_002123940.1 1643567 R 552526 CDS YP_002123941.1 195978697 6761405 complement(1645200..1645658) 1 NC_011134.1 similar to ref|NP_269711.1| ABC transporter (ATP-binding protein) [Streptococcus pyogenes M1 GAS]; Facilitated transport; ABC transporter ATP-binding protein 1645658 6761405 Sez_1595 Streptococcus equi subsp. zooepidemicus MGCS10565 ABC transporter ATP-binding protein YP_002123941.1 1645200 R 552526 CDS YP_002123942.1 195978698 6761404 complement(1645615..1645932) 1 NC_011134.1 similar to ref|YP_602977.1| ABC transporter ATP-binding protein [Streptococcus pyogenes MGAS10750]; Facilitated transport; ABC transporter ATP-binding protein 1645932 6761404 Sez_1596 Streptococcus equi subsp. zooepidemicus MGCS10565 ABC transporter ATP-binding protein YP_002123942.1 1645615 R 552526 CDS YP_002123943.1 195978699 6761383 complement(1645978..1646235) 1 NC_011134.1 similar to ref|YP_282737.1| hypothetical protein M5005_Spy_1374 [Streptococcus pyogenes MGAS5005]; hypothetical protein 1646235 6761383 Sez_1597 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123943.1 1645978 R 552526 CDS YP_002123944.1 195978700 6761375 complement(1648232..1650220) 1 NC_011134.1 catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase; transketolase 1650220 tkt 6761375 tkt Streptococcus equi subsp. zooepidemicus MGCS10565 transketolase YP_002123944.1 1648232 R 552526 CDS YP_002123945.1 195978701 6761371 complement(1650434..1650571) 1 NC_011134.1 hypothetical protein 1650571 6761371 Sez_1601 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123945.1 1650434 R 552526 CDS YP_002123946.1 195978702 6761369 complement(1650605..1651249) 1 NC_011134.1 similar to novel fructose-6-phosphate aldolase from Escherichia coli; enzyme from Methanocaldococcus janaschii shows transaldolase activity; translaldolase 1651249 tal 6761369 tal Streptococcus equi subsp. zooepidemicus MGCS10565 translaldolase YP_002123946.1 1650605 R 552526 CDS YP_002123947.1 195978703 6761393 complement(1651423..1652928) 1 NC_011134.1 Converts glycerol and ADP to glycerol-3-phosphate and ADP; glycerol kinase 1652928 glpK 6761393 glpK Streptococcus equi subsp. zooepidemicus MGCS10565 glycerol kinase YP_002123947.1 1651423 R 552526 CDS YP_002123948.1 195978704 6761365 complement(1653030..1653182) 1 NC_011134.1 hypothetical protein 1653182 6761365 Sez_1604 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123948.1 1653030 R 552526 CDS YP_002123949.1 195978705 6761391 complement(1653266..1653847) 1 NC_011134.1 similar to ref|YP_001127997.1| lipoprotein [Streptococcus pyogenes str. Manfredo]; hypothetical protein 1653847 6761391 Sez_1605 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123949.1 1653266 R 552526 CDS YP_002123950.1 195978706 6761362 complement(1654772..1654966) 1 NC_011134.1 similar to gb|AAM90904.2|AF493605_7 BlpM-like protein [Streptococcus pyogenes]; bacteriocin-like peptide 1654966 6761362 Sez_1606 Streptococcus equi subsp. zooepidemicus MGCS10565 bacteriocin-like peptide YP_002123950.1 1654772 R 552526 CDS YP_002123951.1 195978707 6761382 complement(1655473..1656339) 1 NC_011134.1 similar to ref|YP_281699.1| corrin/porphyrin methyltransferase [Streptococcus pyogenes MGAS5005]; tetrapyrrole (corrin-porphyrin) methylase family protein 1656339 6761382 Sez_1607 Streptococcus equi subsp. zooepidemicus MGCS10565 tetrapyrrole (corrin-porphyrin) methylase family protein YP_002123951.1 1655473 R 552526 CDS YP_002123952.1 195978708 6761380 complement(1656344..1656667) 1 NC_011134.1 in Bacillus subtilis this protein is involved in the negative regulation of DNA replication initiation; interacts with DnaN and DnaA; DNA replication intiation control protein YabA 1656667 yabA 6761380 yabA Streptococcus equi subsp. zooepidemicus MGCS10565 DNA replication intiation control protein YabA YP_002123952.1 1656344 R 552526 CDS YP_002123953.1 195978709 6761619 complement(1656660..1657460) 1 NC_011134.1 similar to ref|NP_721994.1| signal peptidase II [Streptococcus mutans UA159]; Essential for the phosphorelay during initiation of sporulation. May control the level of phosphorylated spo0A through spo0E activity during sporulation.; stage 0 sporulation protein YaaT-like 1657460 yaaT 6761619 yaaT Streptococcus equi subsp. zooepidemicus MGCS10565 stage 0 sporulation protein YaaT-like YP_002123953.1 1656660 R 552526 CDS YP_002123954.1 195978710 6761591 complement(1657457..1658332) 1 NC_011134.1 catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the delta' subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA.; DNA polymerase III subunit delta' 1658332 holB 6761591 holB Streptococcus equi subsp. zooepidemicus MGCS10565 DNA polymerase III subunit delta' YP_002123954.1 1657457 R 552526 CDS YP_002123955.1 195978711 6761616 complement(1658346..1659044) 1 NC_011134.1 catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to thymidine monophosphate (dTMP) to form thymidine diphosphate (dTDP); thymidylate kinase 1659044 tmk 6761616 tmk Streptococcus equi subsp. zooepidemicus MGCS10565 thymidylate kinase YP_002123955.1 1658346 R 552526 CDS YP_002123956.1 195978712 6761609 complement(1659297..1659581) 1 NC_011134.1 similar to ref|YP_596061.1| hypothetical protein MGAS9429_Spy0329 [Streptococcus pyogenes MGAS9429]; hypothetical protein 1659581 6761609 Sez_1612 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123956.1 1659297 R 552526 CDS YP_002123957.1 195978713 6761606 complement(1659582..1660028) 1 NC_011134.1 similar to ref|NP_722004.1| hypothetical protein SMU.1671c [Streptococcus mutans UA159]; hypothetical protein 1660028 6761606 Sez_1613 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123957.1 1659582 R 552526 CDS YP_002123958.1 195978714 6761605 complement(1660133..1660756) 1 NC_011134.1 hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates; ATP-dependent Clp protease proteolytic subunit 1660756 clpP 6761605 clpP Streptococcus equi subsp. zooepidemicus MGCS10565 ATP-dependent Clp protease proteolytic subunit YP_002123958.1 1660133 R 552526 CDS YP_002123959.1 195978715 6761579 complement(1660955..1661584) 1 NC_011134.1 Catalyzes the formation of uracil and 5-phospho-alpha-D-ribosy 1-diphosphate from UMP and diphosphate; uracil phosphoribosyltransferase 1661584 upp 6761579 upp Streptococcus equi subsp. zooepidemicus MGCS10565 uracil phosphoribosyltransferase YP_002123959.1 1660955 R 552526 CDS YP_002123960.1 195978716 6761601 complement(1661734..1663365) 1 NC_011134.1 similar to ref|YP_059670.1| Export protein for polysaccharides and teichoic acids [Streptococcus pyogenes MGAS10394]; export protein for polysaccharides and teichoic acids 1663365 6761601 Sez_1616 Streptococcus equi subsp. zooepidemicus MGCS10565 export protein for polysaccharides and teichoic acids YP_002123960.1 1661734 R 552526 CDS YP_002123961.1 195978717 6761599 1663451..1664896 1 NC_011134.1 involved in cell wall formation; peptidoglycan synthesis; cytoplasmic enzyme; catalyzes the addition of lysine to UDP-N-acetylmuramoyl-L-alanyl-D-glutamate forming UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysine; UDP-N-acetylmuramoylalanyl-D-glutamate--L-lysine ligase 1664896 murE 6761599 murE Streptococcus equi subsp. zooepidemicus MGCS10565 UDP-N-acetylmuramoylalanyl-D-glutamate--L-lysine ligase YP_002123961.1 1663451 D 552526 CDS YP_002123962.1 195978718 6761598 1665156..1665935 1 NC_011134.1 similar to ref|ZP_00365817.1| COG1120: ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components [Streptococcus pyogenes M49 591]; Part of the binding-protein-dependent transport system for Fe(3+)-ferrichrome. Probably responsible for energy coupling to the transport system.; ferrichrome ABC transporter ATP-binding protein 1665935 fhuC 6761598 fhuC Streptococcus equi subsp. zooepidemicus MGCS10565 ferrichrome ABC transporter ATP-binding protein YP_002123962.1 1665156 D 552526 CDS YP_002123963.1 195978719 6761574 1665960..1666898 1 NC_011134.1 similar to ref|NP_268705.1| ferrichrome ABC transporter (ferrichrome-binding protein) [Streptococcus pyogenes M1 GAS]; This is one of the proteins involved in the high-affinity transport of Fe(3+)-ferrichrome into the cell.; ferrichrome-binding lipoprotein precursor FhuD 1666898 fhuD 6761574 fhuD Streptococcus equi subsp. zooepidemicus MGCS10565 ferrichrome-binding lipoprotein precursor FhuD YP_002123963.1 1665960 D 552526 CDS YP_002123964.1 195978720 6761593 1666882..1667934 1 NC_011134.1 similar to ref|YP_001129059.1| ferrichrome transport permease [Streptococcus pyogenes str. Manfredo]; This is one of the proteins involved in the high- affinity transport of Fe(3+)-ferrichrome into the cell.; ferrichrome ABC transporter permease 1667934 fhuB 6761593 fhuB Streptococcus equi subsp. zooepidemicus MGCS10565 ferrichrome ABC transporter permease YP_002123964.1 1666882 D 552526 CDS YP_002123965.1 195978721 6761592 1667931..1668929 1 NC_011134.1 similar to ref|NP_802841.1| ferrichrome ABC transporter (permease) [Streptococcus pyogenes SSI-1]; This is one of the proteins involved in the high- affinity transport of Fe(3+)-ferrichrome into the cell.; ferrichrome ABC transporter permease 1668929 fhuG 6761592 fhuG Streptococcus equi subsp. zooepidemicus MGCS10565 ferrichrome ABC transporter permease YP_002123965.1 1667931 D 552526 CDS YP_002123966.1 195978722 6761521 1669309..1669437 1 NC_011134.1 hypothetical protein 1669437 6761521 Sez_1622 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123966.1 1669309 D 552526 CDS YP_002123967.1 195978723 6761586 complement(1669666..1670319) 1 NC_011134.1 similar to ref|YP_601808.1| hypothetical cytosolic protein [Streptococcus pyogenes MGAS10750]; hypothetical protein 1670319 6761586 Sez_1623 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123967.1 1669666 R 552526 CDS YP_002123968.1 195978724 6761584 complement(1670386..1671321) 1 NC_011134.1 catalyzes the hydrolysis of pyrophosphate to phosphate; manganese-dependent inorganic pyrophosphatase 1671321 6761584 Sez_1624 Streptococcus equi subsp. zooepidemicus MGCS10565 manganese-dependent inorganic pyrophosphatase YP_002123968.1 1670386 R 552526 CDS YP_002123969.1 195978725 6761578 complement(1671806..1672597) 1 NC_011134.1 similar to ref|NP_606672.1| pyruvate-formatelyase activating enzyme [Streptococcus pyogenes MGAS8232]; Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.; pyruvate formate-lyase-activating enzyme 1672597 6761578 Sez_1625 Streptococcus equi subsp. zooepidemicus MGCS10565 pyruvate formate-lyase-activating enzyme YP_002123969.1 1671806 R 552526 CDS YP_002123970.1 195978726 6761576 complement(1672674..1674008) 1 NC_011134.1 similar to ref|YP_279775.1| hemolysin [Streptococcus pyogenes MGAS6180]; hemolysins and related proteins containing CBS domains, magnesium and cobalt efflux protein 1674008 6761576 Sez_1626 Streptococcus equi subsp. zooepidemicus MGCS10565 hemolysins and related proteins containing CBS domains, magnesium and cobalt efflux protein YP_002123970.1 1672674 R 552526 CDS YP_002123971.1 195978727 6761577 complement(1674136..1674693) 1 NC_011134.1 similar to ref|YP_279774.1| SAM-dependent methyltransferase [Streptococcus pyogenes MGAS6180]; SAM-dependent methyltransferase 1674693 6761577 Sez_1627 Streptococcus equi subsp. zooepidemicus MGCS10565 SAM-dependent methyltransferase YP_002123971.1 1674136 R 552526 CDS YP_002123972.1 195978728 6761575 complement(1674703..1675428) 1 NC_011134.1 similar to ref|YP_194206.1| kanamycin kinase [Lactobacillus acidophilus NCFM]; aminoglycoside 3'-phosphotransferase 1675428 6761575 Sez_1628 Streptococcus equi subsp. zooepidemicus MGCS10565 aminoglycoside 3'-phosphotransferase YP_002123972.1 1674703 R 552526 CDS YP_002123973.1 195978729 6761573 complement(1675501..1676424) 1 NC_011134.1 similar to ref|YP_596046.1| radical SAM superfamily protein [Streptococcus pyogenes MGAS9429]; Fe-S oxidoreductase 1676424 6761573 Sez_1629 Streptococcus equi subsp. zooepidemicus MGCS10565 Fe-S oxidoreductase YP_002123973.1 1675501 R 552526 CDS YP_002123974.1 195978730 6761554 complement(1676616..1677239) 1 NC_011134.1 similar to ref|YP_596045.1| membrane-associated phospholipid phosphatase [Streptococcus pyogenes MGAS9429]; membrane-associated phospholipid phosphatase PAP2 Family Protein 1677239 6761554 Sez_1630 Streptococcus equi subsp. zooepidemicus MGCS10565 membrane-associated phospholipid phosphatase PAP2 Family Protein YP_002123974.1 1676616 R 552526 CDS YP_002123975.1 195978731 6761571 complement(1677253..1677855) 1 NC_011134.1 similar to ref|YP_279771.1| riboflavin transporter [Streptococcus pyogenes MGAS6180]; riboflavin transporter YpaA-like 1677855 ypaA 6761571 ypaA Streptococcus equi subsp. zooepidemicus MGCS10565 riboflavin transporter YpaA-like YP_002123975.1 1677253 R 552526 CDS YP_002123976.1 195978732 6761572 complement(1678617..1678931) 1 NC_011134.1 similar to ref|ZP_00785752.1| Unknown [Streptococcus agalactiae COH1]; hypothetical protein 1678931 6761572 Sez_1632 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123976.1 1678617 R 552526 CDS YP_002123977.1 195978733 6761551 complement(1678921..1680117) 1 NC_011134.1 similar to ref|NP_736400.1| hypothetical protein gbs1967 [Streptococcus agalactiae NEM316]; hypothetical protein 1680117 6761551 Sez_1633 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123977.1 1678921 R 552526 CDS YP_002123978.1 195978734 6761550 complement(1680594..1680893) 1 NC_011134.1 similar to ref|YP_849451.1| hypothetical protein lwe1254 [Listeria welshimeri serovar 6b str. SLCC5334]; hypothetical protein 1680893 6761550 Sez_1634 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123978.1 1680594 R 552526 CDS YP_002123979.1 195978735 6761546 complement(1681215..1681505) 1 NC_011134.1 similar to ref|ZP_00874487.1| similar to unknown proteins [Streptococcus suis 89/1591]; hypothetical protein 1681505 6761546 Sez_1635 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123979.1 1681215 R 552526 CDS YP_002123980.1 195978736 6761562 complement(1681502..1681870) 1 NC_011134.1 similar to ref|NP_736401.1| hypothetical protein gbs1968 [Streptococcus agalactiae NEM316]; hypothetical protein 1681870 6761562 Sez_1636 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123980.1 1681502 R 552526 CDS YP_002123981.1 195978737 6761534 complement(1682177..1682599) 1 NC_011134.1 similar to ref|NP_736401.1| hypothetical protein gbs1968 [Streptococcus agalactiae NEM316]; hypothetical protein 1682599 6761534 Sez_1637 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123981.1 1682177 R 552526 CDS YP_002123982.1 195978738 6761540 complement(1682979..1683578) 1 NC_011134.1 similar to ref|YP_059656.1| 23S rRNA methyltransferase [Streptococcus pyogenes MGAS10394]; tRNA (cytosine34-2'-O-)-methyltransferase 1683578 6761540 Sez_1638 Streptococcus equi subsp. zooepidemicus MGCS10565 tRNA (cytosine34-2'-O-)-methyltransferase YP_002123982.1 1682979 R 552526 CDS YP_002123983.1 195978739 6761558 complement(1683686..1683964) 1 NC_011134.1 similar to ref|NP_606663.1| hypothetical protein spyM18_0419 [Streptococcus pyogenes MGAS8232]; hypothetical protein 1683964 6761558 Sez_1639 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123983.1 1683686 R 552526 CDS YP_002123984.1 195978740 6761555 complement(1683961..1684761) 1 NC_011134.1 similar to ref|YP_279768.1| ribosomal large subunit pseudouridine synthase B [Streptococcus pyogenes MGAS6180]; Responsible for synthesis of pseudouridine from uracil- 2633 in 23S ribosomal RNA.; ribosomal large subunit pseudouridine synthase B RluB 1684761 rluB 6761555 rluB Streptococcus equi subsp. zooepidemicus MGCS10565 ribosomal large subunit pseudouridine synthase B RluB YP_002123984.1 1683961 R 552526 CDS YP_002123985.1 195978741 6761530 complement(1684929..1685468) 1 NC_011134.1 functions during chromosome segregation; may form a condensin-like structure with SMC and ScpA; forms a homodimer; segregation and condensation protein B 1685468 scpB 6761530 scpB Streptococcus equi subsp. zooepidemicus MGCS10565 segregation and condensation protein B YP_002123985.1 1684929 R 552526 CDS YP_002123986.1 195978742 6761549 complement(1685465..1686172) 1 NC_011134.1 functions during chromosome segregation; may form a condensin-like structure with SMC and ScpB; segregation and condensation protein A 1686172 scpA 6761549 scpA Streptococcus equi subsp. zooepidemicus MGCS10565 segregation and condensation protein A YP_002123986.1 1685465 R 552526 CDS YP_002123987.1 195978743 6761520 complement(1686172..1686918) 1 NC_011134.1 site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs; site-specific tyrosine recombinase XerD 1686918 xerD 6761520 xerD Streptococcus equi subsp. zooepidemicus MGCS10565 site-specific tyrosine recombinase XerD YP_002123987.1 1686172 R 552526 CDS YP_002123988.1 195978744 6761547 complement(1686915..1687376) 1 NC_011134.1 similar to ref|YP_279764.1| CBS domain containing protein [Streptococcus pyogenes MGAS6180]; hypothetical protein 1687376 6761547 Sez_1644 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123988.1 1686915 R 552526 CDS YP_002123989.1 195978745 6761544 complement(1687373..1687870) 1 NC_011134.1 similar to ref|ZP_00366310.1| COG0622: Predicted phosphoesterase [Streptococcus pyogenes M49 591]; metallophosphoesterase 1687870 6761544 Sez_1645 Streptococcus equi subsp. zooepidemicus MGCS10565 metallophosphoesterase YP_002123989.1 1687373 R 552526 CDS YP_002123990.1 195978746 6761541 complement(1687870..1688859) 1 NC_011134.1 HAM1-like protein; Rec-dependent growth; RgdB; yggV; it is suspected that this protein functions to remove misincorporated bases such as xanthine or hypoxanthine; deoxyribonucleotide triphosphate pyrophosphatase/hypothetical protein 1688859 6761541 Sez_1646 Streptococcus equi subsp. zooepidemicus MGCS10565 deoxyribonucleotide triphosphate pyrophosphatase/hypothetical protein YP_002123990.1 1687870 R 552526 CDS YP_002123991.1 195978747 6761535 complement(1688856..1689734) 1 NC_011134.1 converts L-glutamate to D-glutamate, a component of peptidoglycan; glutamate racemase 1689734 murI 6761535 murI Streptococcus equi subsp. zooepidemicus MGCS10565 glutamate racemase YP_002123991.1 1688856 R 552526 CDS YP_002123992.1 195978748 6761536 complement(1689830..1690072) 1 NC_011134.1 similar to ref|NP_268684.1| hypothetical protein SPy_0359 [Streptococcus pyogenes M1 GAS]; hypothetical protein 1690072 6761536 Sez_1648 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123992.1 1689830 R 552526 CDS YP_002123993.1 195978749 6761539 complement(1690470..1691162) 1 NC_011134.1 similar to ref|ZP_00366306.1| COG0670: Integral membrane protein, interacts with FtsH [Streptococcus pyogenes M49 591]; hypothetical protein 1691162 6761539 Sez_1649 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002123993.1 1690470 R 552526 CDS YP_002123994.1 195978750 6761531 complement(1691178..1691678) 1 NC_011134.1 similar to ref|YP_597903.1| Hydrolase [Streptococcus pyogenes MGAS10270]; hydrolase 1691678 6761531 Sez_1650 Streptococcus equi subsp. zooepidemicus MGCS10565 hydrolase YP_002123994.1 1691178 R 552526 CDS YP_002123995.1 195978751 6761528 complement(1691716..1692453) 1 NC_011134.1 similar to ref|NP_664062.1| spoU rRNA Methylase family protein [Streptococcus pyogenes MGAS315]; RNA methyltransferase TrmH family 1692453 6761528 Sez_1651 Streptococcus equi subsp. zooepidemicus MGCS10565 RNA methyltransferase TrmH family YP_002123995.1 1691716 R 552526 CDS YP_002123996.1 195978752 6761499 1692844..1694565 1 NC_011134.1 similar to ref|ZP_01371554.1| transposase, IS4 [Desulfitobacterium hafniense DCB-2]; transposase IS4-like 1694565 6761499 Sez_1652 Streptococcus equi subsp. zooepidemicus MGCS10565 transposase IS4-like YP_002123996.1 1692844 D 552526 CDS YP_002123997.1 195978753 6761518 1694913..1695191 1 NC_011134.1 catalyzes the hydrolysis of acylphosphate; acylphosphatase 1695191 6761518 Sez_1653 Streptococcus equi subsp. zooepidemicus MGCS10565 acylphosphatase YP_002123997.1 1694913 D 552526 CDS YP_002123998.1 195978754 6761517 1695274..1696194 1 NC_011134.1 involved in biogenesis of membrane proteins; Firmicutes specific proteins are shorter than other bacterial counterparts and have a signal peptide and lipid attachment site; OxaA-like protein precursor 1696194 oxaA2 6761517 oxaA2 Streptococcus equi subsp. zooepidemicus MGCS10565 OxaA-like protein precursor YP_002123998.1 1695274 D 552526 CDS YP_002123999.1 195978755 6761516 complement(1696451..1696981) 1 NC_011134.1 necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus; transcription elongation factor GreA 1696981 greA 6761516 greA Streptococcus equi subsp. zooepidemicus MGCS10565 transcription elongation factor GreA YP_002123999.1 1696451 R 552526 CDS YP_002124000.1 195978756 6761515 complement(1697006..1698574) 1 NC_011134.1 similar to ref|ZP_00366469.1| COG1559: Predicted periplasmic solute-binding protein [Streptococcus pyogenes M49 591]; aminodeoxychorismate lyase 1698574 6761515 Sez_1656 Streptococcus equi subsp. zooepidemicus MGCS10565 aminodeoxychorismate lyase YP_002124000.1 1697006 R 552526 CDS YP_002124001.1 195978757 6761514 complement(1698671..1699150) 1 NC_011134.1 similar to ref|ZP_00366468.1| COG0454: Histone acetyltransferase HPA2 and related acetyltransferases [Streptococcus pyogenes M49 591]; arylalkylamine n-acetyltransferase 1699150 6761514 Sez_1657 Streptococcus equi subsp. zooepidemicus MGCS10565 arylalkylamine n-acetyltransferase YP_002124001.1 1698671 R 552526 CDS YP_002124002.1 195978758 6761513 complement(1699213..1700544) 1 NC_011134.1 Catalyzes the formation of UDP-N-acetylmuramoyl-L-alanine from UDP-N-acetylmuramate and L-alanine in peptidoglycan synthesis; UDP-N-acetylmuramate--L-alanine ligase 1700544 murC 6761513 murC Streptococcus equi subsp. zooepidemicus MGCS10565 UDP-N-acetylmuramate--L-alanine ligase YP_002124002.1 1699213 R 552526 CDS YP_002124003.1 195978759 6761512 complement(1700588..1701181) 1 NC_011134.1 similar to ref|NP_268674.1| hypothetical protein SPy_0343 [Streptococcus pyogenes M1 GAS]; hypothetical protein 1701181 6761512 Sez_1659 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002124003.1 1700588 R 552526 CDS YP_002124004.1 195978760 6761511 complement(1701385..1704489) 1 NC_011134.1 similar to ref|YP_059634.1| SWF/SNF family helicase [Streptococcus pyogenes MGAS10394]; SWF/SNF family helicase 1704489 6761511 Sez_1660 Streptococcus equi subsp. zooepidemicus MGCS10565 SWF/SNF family helicase YP_002124004.1 1701385 R 552526 CDS YP_002124005.1 195978761 6761509 complement(1704818..1706158) 1 NC_011134.1 EngA; essential Neisserial GTPase; synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains; GTP-binding protein EngA 1706158 engA 6761509 engA Streptococcus equi subsp. zooepidemicus MGCS10565 GTP-binding protein EngA YP_002124005.1 1704818 R 552526 CDS YP_002124006.1 195978762 6761503 complement(1706178..1707086) 1 NC_011134.1 Primosomal protein that may act to load helicase DnaC during DNA replication; primosomal protein DnaI 1707086 dnaI 6761503 dnaI Streptococcus equi subsp. zooepidemicus MGCS10565 primosomal protein DnaI YP_002124006.1 1706178 R 552526 CDS YP_002124007.1 195978763 6761502 complement(1707087..1708247) 1 NC_011134.1 similar to ref|YP_059631.1| Replicative DNA helicase [Streptococcus pyogenes MGAS10394]; helicase loader DnaB 1708247 dnaB 6761502 dnaB Streptococcus equi subsp. zooepidemicus MGCS10565 helicase loader DnaB YP_002124007.1 1707087 R 552526 CDS YP_002124008.1 195978764 6761497 complement(1708234..1708728) 1 NC_011134.1 similar to sp|Q5XDR6|NRDR_STRP6 Transcriptional repressor nrdR; NrdR family transcriptional regulator 1708728 nrdR 6761497 nrdR Streptococcus equi subsp. zooepidemicus MGCS10565 NrdR family transcriptional regulator YP_002124008.1 1708234 R 552526 CDS YP_002124009.1 195978765 6761496 complement(1708919..1710409) 1 NC_011134.1 similar to ref|NP_802876.1| two-component sensor histidine kinase (CsrS/CovS) [Streptococcus pyogenes SSI-1]; Member of the two-component regulatory system CovR/CovS involved in the regulation of multiple virulence factors.; TCS sensor kinase CovS-like 1710409 covS 6761496 covS Streptococcus equi subsp. zooepidemicus MGCS10565 TCS sensor kinase CovS-like YP_002124009.1 1708919 R 552526 CDS YP_002124010.1 195978766 6761495 complement(1710413..1711099) 1 NC_011134.1 similar to ref|NP_802877.1| two-component response regulator (CsrR/CovR) [Streptococcus pyogenes SSI-1]; Member of the two-component regulatory system CovR/CovS involved in the regulation of multiple virulence factors.; TCS response regulator CovR-like 1711099 covR 6761495 covR Streptococcus equi subsp. zooepidemicus MGCS10565 TCS response regulator CovR-like YP_002124010.1 1710413 R 552526 CDS YP_002124011.1 195978767 6761488 complement(1711285..1711818) 1 NC_011134.1 similar to ref|YP_001129097.1| hypothetical protein SpyM51574 [Streptococcus pyogenes str. Manfredo]; hypothetical protein 1711818 6761488 Sez_1667 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002124011.1 1711285 R 552526 CDS YP_002124012.1 195978768 6762329 complement(1712106..1712999) 1 NC_011134.1 metalloprotease; heat shock protein HtpX 1712999 htpX 6762329 htpX Streptococcus equi subsp. zooepidemicus MGCS10565 heat shock protein HtpX YP_002124012.1 1712106 R 552526 CDS YP_002124013.1 195978769 6761374 complement(1713031..1713582) 1 NC_011134.1 similar to ref|YP_001129099.1| LemA family protein [Streptococcus pyogenes str. Manfredo]; cytoplasmic membrane protein LemA 1713582 6761374 Sez_1669 Streptococcus equi subsp. zooepidemicus MGCS10565 cytoplasmic membrane protein LemA YP_002124013.1 1713031 R 552526 CDS YP_002124014.1 195978770 6761875 1713724..1714437 1 NC_011134.1 glucose-inhibited division protein B; SAM-dependent methyltransferase; methylates the N7 position of guanosine in position 527 of 16S rRNA; 16S rRNA methyltransferase GidB 1714437 gidB 6761875 gidB Streptococcus equi subsp. zooepidemicus MGCS10565 16S rRNA methyltransferase GidB YP_002124014.1 1713724 D 552526 CDS YP_002124015.1 195978771 6762222 1714971..1716347 1 NC_011134.1 similar to ref|YP_601766.1| Potassium uptake protein ktrB [Streptococcus pyogenes MGAS10750]; potassium uptake protein KtrB 1716347 ktrB 6762222 ktrB Streptococcus equi subsp. zooepidemicus MGCS10565 potassium uptake protein KtrB YP_002124015.1 1714971 D 552526 CDS YP_002124016.1 195978772 6760834 1716357..1717031 1 NC_011134.1 similar to ref|YP_601765.1| Potassium uptake protein ktrA [Streptococcus pyogenes MGAS10750]; potassium uptake protein KtrA 1717031 ktrA 6760834 ktrA Streptococcus equi subsp. zooepidemicus MGCS10565 potassium uptake protein KtrA YP_002124016.1 1716357 D 552526 CDS YP_002124017.1 195978773 6760393 complement(1717224..1718438) 1 NC_011134.1 involved in the import of serine and threonine coupled with the import of sodium; serine/threonine transporter SstT 1718438 6760393 Sez_1673 Streptococcus equi subsp. zooepidemicus MGCS10565 serine/threonine transporter SstT YP_002124017.1 1717224 R 552526 CDS YP_002124018.1 195978774 6760819 complement(1720297..1720989) 1 NC_011134.1 similar to ref|NP_664039.1| ABC transporter (permease) [Streptococcus pyogenes MGAS315]; Part of the binding-protein-dependent transport system for D-methionine. Probably responsible for the translocation of the substrate across the membrane.; D-methionine transport system permease MetI 1720989 metI 6760819 metI Streptococcus equi subsp. zooepidemicus MGCS10565 D-methionine transport system permease MetI YP_002124018.1 1720297 R 552526 CDS YP_002124019.1 195978775 6760656 complement(1720990..1722042) 1 NC_011134.1 similar to ref|YP_596003.1| ABC transporter ATP-binding protein [Streptococcus pyogenes MGAS9429]; Part of the binding-protein-dependent transport system metNIQ for D-methionine and the toxic methionine analog alpha- methyl-methionine. Probably responsible for energy coupling to the transport system.; D-methionine transport ATP-binding protein MetN 1722042 metN 6760656 metN Streptococcus equi subsp. zooepidemicus MGCS10565 D-methionine transport ATP-binding protein MetN YP_002124019.1 1720990 R 552526 CDS YP_002124020.1 195978776 6760377 complement(1722047..1723417) 1 NC_011134.1 similar to gb|AAN59550.1|AE015018_4 peptidase, AtmC; ArgE/DapE/Acy1 family protein [Streptococcus mutans UA159]; Catalysis of the reaction: N-acyl-L-amino acid + H2O = carboxylate + L-amino acid.; N-acyl-L-amino acid amidohydrolase 1723417 6760377 Sez_1678 Streptococcus equi subsp. zooepidemicus MGCS10565 N-acyl-L-amino acid amidohydrolase YP_002124020.1 1722047 R 552526 CDS YP_002124021.1 195978777 6760486 complement(1723490..1724335) 1 NC_011134.1 similar to ref|YP_279732.1| ABC transporter substrate-binding protein [Streptococcus pyogenes MGAS6180]; This protein is a component of a D-methionine permease, a binding protein-dependent, ATP-driven transport system.; D-methionine-binding lipoprotein MetQ 1724335 metQ 6760486 metQ Streptococcus equi subsp. zooepidemicus MGCS10565 D-methionine-binding lipoprotein MetQ YP_002124021.1 1723490 R 552526 CDS YP_002124022.1 195978778 6760815 complement(1724696..1725541) 1 NC_011134.1 similar to ref|YP_059616.1| ABC transporter substrate-binding protein [Streptococcus pyogenes MGAS10394]; Probably part of a binding-protein-dependent transport system for an amino acid.; amino-acid ABC transporter-binding lipoprotein precursor 1725541 6760815 Sez_1680 Streptococcus equi subsp. zooepidemicus MGCS10565 amino-acid ABC transporter-binding lipoprotein precursor YP_002124022.1 1724696 R 552526 CDS YP_002124023.1 195978779 6760462 complement(1725763..1726479) 1 NC_011134.1 similar to ref|YP_059615.1| hypothetical protein M6_Spy0297 [Streptococcus pyogenes MGAS10394]; hypothetical protein 1726479 6760462 Sez_1681 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002124023.1 1725763 R 552526 CDS YP_002124024.1 195978780 6760472 complement(1726620..1727390) 1 NC_011134.1 similar to ref|ZP_00790359.1| MerR family transcriptional regulator [Streptococcus agalactiae 515]; Transcriptional activator.; MerR family transcriptional regulator 1727390 6760472 Sez_1682 Streptococcus equi subsp. zooepidemicus MGCS10565 MerR family transcriptional regulator YP_002124024.1 1726620 R 552526 CDS YP_002124025.1 195978781 6760428 complement(1727691..1728791) 1 NC_011134.1 similar to ref|YP_595998.1| hypothetical cytosolic protein [Streptococcus pyogenes MGAS9429]; hypothetical protein 1728791 6760428 Sez_1683 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002124025.1 1727691 R 552526 CDS YP_002124026.1 195978782 6760843 complement(1728901..1729644) 1 NC_011134.1 similar to ref|YP_281630.1| methyltransferase [Streptococcus pyogenes MGAS5005]; ubiquinone/menaquinone biosynthesis methyltransferase 1729644 6760843 Sez_1684 Streptococcus equi subsp. zooepidemicus MGCS10565 ubiquinone/menaquinone biosynthesis methyltransferase YP_002124026.1 1728901 R 552526 CDS YP_002124027.1 195978783 6760852 complement(1729774..1730127) 1 NC_011134.1 similar to ref|YP_601754.1| iojap protein family [Streptococcus pyogenes MGAS10750]; Iojap-related protein 1730127 6760852 Sez_1685 Streptococcus equi subsp. zooepidemicus MGCS10565 Iojap-related protein YP_002124027.1 1729774 R 552526 CDS YP_002124028.1 195978784 6762192 complement(1730129..1730719) 1 NC_011134.1 similar to ref|ZP_00366134.1| COG1713: Predicted HD superfamily hydrolase involved in NAD metabolism [Streptococcus pyogenes M49 591]; hydrolase HAD superfamily 1730719 6762192 Sez_1686 Streptococcus equi subsp. zooepidemicus MGCS10565 hydrolase HAD superfamily YP_002124028.1 1730129 R 552526 CDS YP_002124029.1 195978785 6762203 complement(1730719..1731318) 1 NC_011134.1 transfers an adenyl group from ATP to NaMN to form nicotinic acid adenine dinucleotide (NaAD) which is then converted to the ubiquitous compound NAD by NAD synthetase; essential enzyme in bacteria; nicotinic acid mononucleotide adenylyltransferase 1731318 nadD 6762203 nadD Streptococcus equi subsp. zooepidemicus MGCS10565 nicotinic acid mononucleotide adenylyltransferase YP_002124029.1 1730719 R 552526 CDS YP_002124030.1 195978786 6762201 complement(1731435..1731743) 1 NC_011134.1 similar to ref|YP_059608.1| Hypothetical RNA binding protein [Streptococcus pyogenes MGAS10394]; RNA binding protein 1731743 6762201 Sez_1688 Streptococcus equi subsp. zooepidemicus MGCS10565 RNA binding protein YP_002124030.1 1731435 R 552526 CDS YP_002124031.1 195978787 6762198 complement(1731770..1732888) 1 NC_011134.1 in Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis; GTP-binding protein YqeH 1732888 6762198 Sez_1689 Streptococcus equi subsp. zooepidemicus MGCS10565 GTP-binding protein YqeH YP_002124031.1 1731770 R 552526 CDS YP_002124032.1 195978788 6762191 complement(1732888..1733460) 1 NC_011134.1 similar to ref|ZP_00365601.1| COG2179: Predicted hydrolase of the HAD superfamily [Streptococcus pyogenes M49 591]; hydrolase HAD subfamily IIIA 1733460 6762191 Sez_1690 Streptococcus equi subsp. zooepidemicus MGCS10565 hydrolase HAD subfamily IIIA YP_002124032.1 1732888 R 552526 CDS YP_002124033.1 195978789 6762187 complement(1733559..1734038) 1 NC_011134.1 similar to ref|NP_664024.1| transcriptional regulator ComX1 [Streptococcus pyogenes MGAS315]; Involved in establishing competence.; competence-specific sigma factor ComX 1734038 comX 6762187 comX Streptococcus equi subsp. zooepidemicus MGCS10565 competence-specific sigma factor ComX YP_002124033.1 1733559 R 552526 CDS YP_002124034.1 195978790 6761191 complement(1734275..1734412) 1 NC_011134.1 hypothetical protein 1734412 6761191 Sez_1692 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002124034.1 1734275 R 552526 CDS YP_002124035.1 195978791 6761115 complement(1739969..1740892) 1 NC_011134.1 similar to ref|YP_597862.1| Oligopeptide transport ATP-binding protein oppF [Streptococcus pyogenes MGAS10270]; Part of the binding-protein-dependent transport system for oligopeptides. Probably responsible for energy coupling to the transport system.; oligopeptide transport ATP-binding protein OppF 1740892 oppF 6761115 oppF Streptococcus equi subsp. zooepidemicus MGCS10565 oligopeptide transport ATP-binding protein OppF YP_002124035.1 1739969 R 552526 CDS YP_002124036.1 195978792 6762164 complement(1740885..1741955) 1 NC_011134.1 similar to ref|YP_601743.1| Oligopeptide transport ATP-binding protein oppD [Streptococcus pyogenes MGAS10750]; Part of the binding-protein-dependent transport system for oligopeptides. Probably responsible for energy coupling to the transport system.; oligopeptide transport ATP-binding protein OppD 1741955 oppD 6762164 oppD Streptococcus equi subsp. zooepidemicus MGCS10565 oligopeptide transport ATP-binding protein OppD YP_002124036.1 1740885 R 552526 CDS YP_002124037.1 195978793 6762162 complement(1741964..1742890) 1 NC_011134.1 similar to ref|YP_599868.1| Oligopeptide transport system permease oppC [Streptococcus pyogenes MGAS2096]; Part of the binding-protein-dependent transport system for oligopeptides; probably responsible for the translocation of the substrate across the membrane.; oligopeptide transport system permease OppC 1742890 oppC 6762162 oppC Streptococcus equi subsp. zooepidemicus MGCS10565 oligopeptide transport system permease OppC YP_002124037.1 1741964 R 552526 CDS YP_002124038.1 195978794 6762152 complement(1742890..1744389) 1 NC_011134.1 similar to ref|YP_001035872.1| Oligopeptide transport system permease, [Streptococcus sanguinis SK36]; Part of the binding-protein-dependent transport system for oligopeptides; probably responsible for the translocation of the substrate across the membrane.; oligopeptide transport system permease OppB 1744389 oppB 6762152 oppB Streptococcus equi subsp. zooepidemicus MGCS10565 oligopeptide transport system permease OppB YP_002124038.1 1742890 R 552526 CDS YP_002124039.1 195978795 6762156 complement(1744453..1746429) 1 NC_011134.1 similar to ref|YP_001127821.1| extracellular oligopeptide-binding protein [Streptococcus pyogenes str. Manfredo]; Part of the binding-protein-dependent transport system for oligopeptides; probably an oligopeptide binding protein.; oligopeptide ABC transporter periplasmic oligopeptide-binding protein OppA 1746429 oppA 6762156 oppA Streptococcus equi subsp. zooepidemicus MGCS10565 oligopeptide ABC transporter periplasmic oligopeptide-binding protein OppA YP_002124039.1 1744453 R 552526 CDS YP_002124040.1 195978796 6762149 1746689..1747975 1 NC_011134.1 similar to ref|YP_001127820.1| D-alanyl-D-alanine carboxypeptidase [Streptococcus pyogenes str. Manfredo]; Removes C-terminal D-alanyl residues from sugar-peptide cell wall peptidoglycan precursors.; D-alanyl-D-alanine carboxypeptidase 1747975 dacA.1 6762149 dacA.1 Streptococcus equi subsp. zooepidemicus MGCS10565 D-alanyl-D-alanine carboxypeptidase YP_002124040.1 1746689 D 552526 CDS YP_002124041.1 195978797 6762126 1748299..1749534 1 NC_011134.1 similar to ref|NP_687183.1| D-alanyl-D-alanine carboxypeptidase family protein [Streptococcus agalactiae 2603V/R]; Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.; D-alanyl-D-alanine carboxypeptidase 1749534 dacA.2 6762126 dacA.2 Streptococcus equi subsp. zooepidemicus MGCS10565 D-alanyl-D-alanine carboxypeptidase YP_002124041.1 1748299 D 552526 CDS YP_002124042.1 195978798 6762141 1749618..1750799 1 NC_011134.1 similar to ref|YP_597856.1| D-alanyl-D-alanine carboxypeptidase [Streptococcus pyogenes MGAS10270]; Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.; D-alanyl-D-alanine carboxypeptidase 1750799 dacA.3 6762141 dacA.3 Streptococcus equi subsp. zooepidemicus MGCS10565 D-alanyl-D-alanine carboxypeptidase YP_002124042.1 1749618 D 552526 CDS YP_002124043.1 195978799 6762137 complement(1750959..1752377) 1 NC_011134.1 similar to ref|ZP_00365646.1| COG0719: ABC-type transport system involved in Fe-S cluster assembly, permease component [Streptococcus pyogenes M49; iron-sulfur cluster assembly protein SufB 1752377 sufB 6762137 sufB Streptococcus equi subsp. zooepidemicus MGCS10565 iron-sulfur cluster assembly protein SufB YP_002124043.1 1750959 R 552526 CDS YP_002124044.1 195978800 6762113 complement(1752417..1752824) 1 NC_011134.1 similar to ref|YP_281609.1| iscU protein [Streptococcus pyogenes MGAS5005]; May be involved in the formation or repair of [Fe-S] clusters present in iron-sulfur proteins (potential).; iron-sulfur cluster assembly scaffold protein IscU 1752824 iscU 6762113 iscU Streptococcus equi subsp. zooepidemicus MGCS10565 iron-sulfur cluster assembly scaffold protein IscU YP_002124044.1 1752417 R 552526 CDS YP_002124045.1 195978801 6762106 complement(1752841..1754067) 1 NC_011134.1 similar to ref|YP_059593.1| Cysteine desulfhydrase [Streptococcus pyogenes MGAS10394]; Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine.; cysteine desulfurase 1754067 sufS 6762106 sufS Streptococcus equi subsp. zooepidemicus MGCS10565 cysteine desulfurase YP_002124045.1 1752841 R 552526 CDS YP_002124046.1 195978802 6762081 complement(1754094..1755356) 1 NC_011134.1 similar to ref|ZP_00366219.1| COG0719: ABC-type transport system involved in Fe-S cluster assembly, permease component [Streptococcus pyogenes M49 591]; iron-sulfur cluster assembly protein SufD 1755356 sufD 6762081 sufD Streptococcus equi subsp. zooepidemicus MGCS10565 iron-sulfur cluster assembly protein SufD YP_002124046.1 1754094 R 552526 CDS YP_002124047.1 195978803 6762123 complement(1755448..1756218) 1 NC_011134.1 similar to ref|YP_279706.1| ABC transporter ATP-binding protein [Streptococcus pyogenes MGAS6180]; iron-sulfur cluster assembly ABC transporter ATP-binding protein SufC 1756218 sufC 6762123 sufC Streptococcus equi subsp. zooepidemicus MGCS10565 iron-sulfur cluster assembly ABC transporter ATP-binding protein SufC YP_002124047.1 1755448 R 552526 CDS YP_002124048.1 195978804 6762120 complement(1756339..1757499) 1 NC_011134.1 similar to ref|YP_601731.1| UDP-phosphate alpha-N-acetylglucosaminephosphotransferase [Streptococcus pyogenes MGAS10750]; Catalyzes the formation of UDP-PP-N- acetylglucosamine. Involved in the synthesis of anionic cell-wall polymers as it mediates the initiation of the linkage unit formation that appears to be common to the two types of teichoic acids attached to the peptidoglycan of B.subtilis; may also be involved in teichuronic acid biosynthesis ().; UDP-phosphate N-acetylglucosaminyl 1-phosphate transferase RgpG 1757499 rgpG 6762120 rgpG Streptococcus equi subsp. zooepidemicus MGCS10565 UDP-phosphate N-acetylglucosaminyl 1-phosphate transferase RgpG YP_002124048.1 1756339 R 552526 CDS YP_002124049.1 195978805 6762116 complement(1757503..1758267) 1 NC_011134.1 enables recognition and targeting of proteins for proteolysis, involved in negative regulation of competence; adaptor protein 1758267 mecA 6762116 mecA Streptococcus equi subsp. zooepidemicus MGCS10565 adaptor protein YP_002124049.1 1757503 R 552526 CDS YP_002124050.1 195978806 6762090 complement(1758387..1759226) 1 NC_011134.1 BacA; phosphatase activity in Escherichia coli not kinase; involved in bacitracin resistance as bacitracin supposedly sequesters UDP disphosphate which reduces the pool of lipid carrier available to the cell; UDP pyrophosphate phosphatase 1759226 uppP 6762090 uppP Streptococcus equi subsp. zooepidemicus MGCS10565 UDP pyrophosphate phosphatase YP_002124050.1 1758387 R 552526 CDS YP_002124051.1 195978807 6762109 complement(1759238..1759363) 1 NC_011134.1 hypothetical protein 1759363 6762109 Sez_1709 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002124051.1 1759238 R 552526 CDS YP_002124052.1 195978808 6762098 1759541..1761109 1 NC_011134.1 similar to ref|NP_606545.1| glutamine-binding periplasmic protein [Streptococcus pyogenes MGAS8232]; Component of high-affinity glutamine permease, a binding-protein-dependent transport system.; amino acid ABC transporter, glutamine-binding protein/permease 1761109 6762098 Sez_1710 Streptococcus equi subsp. zooepidemicus MGCS10565 amino acid ABC transporter, glutamine-binding protein/permease YP_002124052.1 1759541 D 552526 CDS YP_002124053.1 195978809 6762095 1761102..1761842 1 NC_011134.1 similar to ref|YP_059585.1| Amino acid transport ATP-binding protein [Streptococcus pyogenes MGAS10394]; Probably part of a binding-protein-dependent transport system for an amino acid. Probably responsible for energy coupling to the transport system.; amino acid transport ATP-binding protein 1761842 6762095 Sez_1711 Streptococcus equi subsp. zooepidemicus MGCS10565 amino acid transport ATP-binding protein YP_002124053.1 1761102 D 552526 CDS YP_002124054.1 195978810 6762092 complement(1762798..1763763) 1 NC_011134.1 similar to ref|YP_603153.1| Membrane protease family [Streptococcus pyogenes MGAS10750]; stomatin/prohibitin-family membrane protease subunit 1763763 6762092 Sez_1712 Streptococcus equi subsp. zooepidemicus MGCS10565 stomatin/prohibitin-family membrane protease subunit YP_002124054.1 1762798 R 552526 CDS YP_002124055.1 195978811 6762067 1763777..1763929 1 NC_011134.1 hypothetical protein 1763929 6762067 Sez_1713 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002124055.1 1763777 D 552526 CDS YP_002124056.1 195978812 6762002 complement(1763951..1765615) 1 NC_011134.1 similar to ref|YP_599282.1| Dihydroxyacetone kinase family protein [Streptococcus pyogenes MGAS10270]; dihydroxyacetone kinase family protein 1765615 6762002 Sez_1714 Streptococcus equi subsp. zooepidemicus MGCS10565 dihydroxyacetone kinase family protein YP_002124056.1 1763951 R 552526 CDS YP_002124057.1 195978813 6762080 complement(1765615..1765980) 1 NC_011134.1 similar to ref|YP_599283.1| General stress protein, Gls24 family [Streptococcus pyogenes MGAS10270]; alkaline-shock protein 1765980 6762080 Sez_1715 Streptococcus equi subsp. zooepidemicus MGCS10565 alkaline-shock protein YP_002124057.1 1765615 R 552526 CDS YP_002124058.1 195978814 6762076 complement(1766132..1766320) 1 NC_011134.1 required for 70S ribosome assembly; 50S ribosomal protein L28 1766320 rpmB 6762076 rpmB Streptococcus equi subsp. zooepidemicus MGCS10565 50S ribosomal protein L28 YP_002124058.1 1766132 R 552526 CDS YP_002124059.1 195978815 6762057 complement(1767275..1768243) 1 NC_011134.1 catalyzes the formation of glycerone phosphate and glyceraldehyde 3-phosphate from fructose 1,6, bisphosphate; fructose-bisphosphate aldolase 1768243 fba 6762057 fba Streptococcus equi subsp. zooepidemicus MGCS10565 fructose-bisphosphate aldolase YP_002124059.1 1767275 R 552526 CDS YP_002124060.1 195978816 6761094 complement(1768496..1769359) 1 NC_011134.1 similar to ref|YP_060935.1| Alpha/beta hydrolase [Streptococcus pyogenes MGAS10394]; alpha/beta hydrolase 1769359 6761094 Sez_1718 Streptococcus equi subsp. zooepidemicus MGCS10565 alpha/beta hydrolase YP_002124060.1 1768496 R 552526 CDS YP_002124061.1 195978817 6762065 1769387..1769530 1 NC_011134.1 hypothetical protein 1769530 6762065 Sez_1719 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002124061.1 1769387 D 552526 CDS YP_002124062.1 195978818 6762061 complement(1769789..1771393) 1 NC_011134.1 CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer; CTP synthetase 1771393 pyrG 6762061 pyrG Streptococcus equi subsp. zooepidemicus MGCS10565 CTP synthetase YP_002124062.1 1769789 R 552526 CDS YP_002124063.1 195978819 6762038 complement(1772500..1773783) 1 NC_011134.1 Tig; RopA; peptidyl-prolyl cis/trans isomerase; promotes folding of newly synthesized proteins; binds ribosomal 50S subunit; forms a homodimer; trigger factor 1773783 tig 6762038 tig Streptococcus equi subsp. zooepidemicus MGCS10565 trigger factor YP_002124063.1 1772500 R 552526 CDS YP_002124064.1 195978820 6762036 complement(1774121..1775530) 1 NC_011134.1 similar to dbj|BAA24177.1| alpha-amylase precursor [Streptococcus bovis]; Endohydrolysis of 1,4-?-D-glucosidic linkages in polysaccharides containing three or more 1,4-?-linked D-glucose units.; alpha-amylase 1775530 amyE 6762036 amyE Streptococcus equi subsp. zooepidemicus MGCS10565 alpha-amylase YP_002124064.1 1774121 R 552526 CDS YP_002124065.1 195978821 6762051 1776028..1776819 1 NC_011134.1 similar to ref|YP_001127832.1| mechanosensitive ion channel protein [Streptococcus pyogenes str. Manfredo]; potassium efflux system / small-conductance mechanosensitive channel 1776819 6762051 Sez_1725 Streptococcus equi subsp. zooepidemicus MGCS10565 potassium efflux system / small-conductance mechanosensitive channel YP_002124065.1 1776028 D 552526 CDS YP_002124066.1 195978822 6762050 complement(1776914..1777474) 1 NC_011134.1 similar to ref|NP_687139.1| conserved hypothetical protein TIGR01440 [Streptococcus agalactiae 2603V/R]; hypothetical protein 1777474 6762050 Sez_1726 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002124066.1 1776914 R 552526 CDS YP_002124067.1 195978823 6761992 complement(1777487..1777960) 1 NC_011134.1 similar to ref|NP_720565.1| hypothetical protein SMU.86 [Streptococcus mutans UA159]; hypothetical protein 1777960 6761992 Sez_1727 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002124067.1 1777487 R 552526 CDS YP_002124068.1 195978824 6762019 complement(1777966..1778715) 1 NC_011134.1 catalyzes the formation of 4-amino-2-methyl-5-diphosphomethylpyrimidine; phosphomethylpyrimidine kinase 1778715 6762019 Sez_1728 Streptococcus equi subsp. zooepidemicus MGCS10565 phosphomethylpyrimidine kinase YP_002124068.1 1777966 R 552526 CDS YP_002124069.1 195978825 6762029 complement(1778705..1779454) 1 NC_011134.1 mediates pseudouridylation (positions 38, 39, 40) at the tRNA anticodon region which contributes to the structural stability; tRNA pseudouridine synthase A 1779454 truA 6762029 truA Streptococcus equi subsp. zooepidemicus MGCS10565 tRNA pseudouridine synthase A YP_002124069.1 1778705 R 552526 CDS YP_002124070.1 195978826 6762012 complement(1779451..1779621) 1 NC_011134.1 hypothetical protein 1779621 6762012 Sez_1730 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002124070.1 1779451 R 552526 CDS YP_002124071.1 195978827 6762027 1779641..1781005 1 NC_011134.1 catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP; lysine and threonine sensitive; aspartate kinase 1781005 6762027 Sez_1731 Streptococcus equi subsp. zooepidemicus MGCS10565 aspartate kinase YP_002124071.1 1779641 D 552526 CDS YP_002124072.1 195978828 6762020 complement(1781096..1781227) 1 NC_011134.1 hypothetical protein 1781227 6762020 Sez_1732 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002124072.1 1781096 R 552526 CDS YP_002124073.1 195978829 6762005 complement(1781484..1781963) 1 NC_011134.1 similar to ref|NP_801488.1| competence protein (ComX1) [Streptococcus pyogenes SSI-1]; competence-specific sigma factor ComX 1781963 comX 6762005 comX Streptococcus equi subsp. zooepidemicus MGCS10565 competence-specific sigma factor ComX YP_002124073.1 1781484 R 552526 CDS YP_002124074.1 195978830 6761108 complement(1782200..1782337) 1 NC_011134.1 hypothetical protein 1782337 6761108 Sez_1734 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002124074.1 1782200 R 552526 CDS YP_002124075.1 195978831 6761172 complement(1788219..1790630) 1 NC_011134.1 similar to ref|YP_329930.1| streptococcal histidine triad family protein [Streptococcus agalactiae A909]; histidine triad protein 1790630 6761172 Sez_1735 Streptococcus equi subsp. zooepidemicus MGCS10565 histidine triad protein YP_002124075.1 1788219 R 552526 CDS YP_002124076.1 195978832 6761989 complement(1790645..1791586) 1 NC_011134.1 similar to ref|NP_608045.1| laminin adhesion [Streptococcus pyogenes MGAS8232]; Part of the ATP-driven transport system adcABC for zinc. Required for transformability.; zinc-binding lipoprotein LraI precursor, laminin-binding protein 1791586 lraI 6761989 lraI Streptococcus equi subsp. zooepidemicus MGCS10565 zinc-binding lipoprotein LraI precursor, laminin-binding protein YP_002124076.1 1790645 R 552526 CDS YP_002124077.1 195978833 6762003 complement(1791898..1793445) 1 NC_011134.1 similar to ref|NP_687786.1| cell wall surface anchor family protein [Streptococcus agalactiae 2603V/R]; cell wall surface anchor family protein 1793445 6762003 Sez_1737 Streptococcus equi subsp. zooepidemicus MGCS10565 cell wall surface anchor family protein YP_002124077.1 1791898 R 552526 CDS YP_002124078.1 195978834 6761998 1793985..1795115 1 NC_011134.1 similar to ref|YP_596508.1| transposase [Streptococcus pyogenes MGAS9429]; transposase IS1548-like 1795115 6761998 Sez_1738 Streptococcus equi subsp. zooepidemicus MGCS10565 transposase IS1548-like YP_002124078.1 1793985 D 552526 CDS YP_002124079.1 195978835 6761994 complement(1795343..1796224) 1 NC_011134.1 similar to ref|NP_816282.1| diacylglycerol kinase catalytic domain protein [Enterococcus faecalis V583]; Catalysis of the reaction: ATP + 1,2-diacylglycerol = ADP + 1,2-diacylglycerol 3-phosphate.; transcriptional regulator 1796224 6761994 Sez_1739 Streptococcus equi subsp. zooepidemicus MGCS10565 transcriptional regulator YP_002124079.1 1795343 R 552526 CDS YP_002124080.1 195978836 6761988 complement(1796389..1797390) 1 NC_011134.1 similar to pir||JC5310 galactose repressor - Streptococcus mutans; Repressor of the galactose operon. Binds galactose as an inducer.; HTH-type transcriptional regulator GalR 1797390 galR 6761988 galR Streptococcus equi subsp. zooepidemicus MGCS10565 HTH-type transcriptional regulator GalR YP_002124080.1 1796389 R 552526 CDS YP_002124081.1 195978837 6761970 1797531..1798703 1 NC_011134.1 catalyzes the formation of alpha-D-galactose 1-phosphate from D-galactose in galactose metabolism; galactokinase 1798703 galK 6761970 galK Streptococcus equi subsp. zooepidemicus MGCS10565 galactokinase YP_002124081.1 1797531 D 552526 CDS YP_002124082.1 195978838 6761960 1798707..1800191 1 NC_011134.1 catalyzes the formation of alpha-D-glucose 1-phosphate and UDP-galactose from UDP-glucose and alpha-D-galactose 1-phosphate in galactose metabolism; galactose-1-phosphate uridylyltransferase 1800191 galT 6761960 galT Streptococcus equi subsp. zooepidemicus MGCS10565 galactose-1-phosphate uridylyltransferase YP_002124082.1 1798707 D 552526 CDS YP_002124083.1 195978839 6762221 1800201..1801211 1 NC_011134.1 similar to ref|NP_688912.1| UDP-glucose 4-epimerase [Streptococcus agalactiae 2603V/R]; Catalysis of the reaction: UDP-glucose = UDP-galactose.; UDP-glucose 4-epimerase GalE 1801211 galE 6762221 galE Streptococcus equi subsp. zooepidemicus MGCS10565 UDP-glucose 4-epimerase GalE YP_002124083.1 1800201 D 552526 CDS YP_002124084.1 195978840 6761871 1801288..1802331 1 NC_011134.1 similar to gb|AAU21551.1| GalM [Streptococcus thermophilus]; Mutarotase converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose.; aldose 1-epimerase 1802331 galM 6761871 galM Streptococcus equi subsp. zooepidemicus MGCS10565 aldose 1-epimerase YP_002124084.1 1801288 D 552526 CDS YP_002124085.1 195978841 6761866 complement(1802829..1803221) 1 NC_011134.1 forms a direct contact with the tRNA during translation; 30S ribosomal protein S9 1803221 rpsI 6761866 rpsI Streptococcus equi subsp. zooepidemicus MGCS10565 30S ribosomal protein S9 YP_002124085.1 1802829 R 552526 CDS YP_002124086.1 195978842 6761862 complement(1803241..1803669) 1 NC_011134.1 in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit; 50S ribosomal protein L13 1803669 rplM 6761862 rplM Streptococcus equi subsp. zooepidemicus MGCS10565 50S ribosomal protein L13 YP_002124086.1 1803241 R 552526 CDS YP_002124087.1 195978843 6761848 1803977..1804930 1 NC_011134.1 similar to ref|YP_138591.1| IS1239 transposase [Streptococcus thermophilus LMG 18311]; transposase IS1239 1804930 6761848 Sez_1747 Streptococcus equi subsp. zooepidemicus MGCS10565 transposase IS1239 YP_002124087.1 1803977 D 552526 CDS YP_002124088.1 195978844 6761737 1804938..1805096 1 NC_011134.1 hypothetical protein 1805096 6761737 Sez_1748 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002124088.1 1804938 D 552526 CDS YP_002124089.1 195978845 6761813 complement(1805310..1806170) 1 NC_011134.1 similar to ref|YP_603238.1| Fatty acid-binding protein, DegV family [Streptococcus pyogenes MGAS10750]; DegV family protein 1806170 6761813 Sez_1749 Streptococcus equi subsp. zooepidemicus MGCS10565 DegV family protein YP_002124089.1 1805310 R 552526 CDS YP_002124090.1 195978846 6761834 complement(1806355..1806873) 1 NC_011134.1 similar to ref|YP_001129143.1| hypothetical protein SpyM51624 [Streptococcus pyogenes str. Manfredo]; hypothetical protein 1806873 6761834 Sez_1750 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002124090.1 1806355 R 552526 CDS YP_002124091.1 195978847 6761830 complement(1806874..1807620) 1 NC_011134.1 similar to ref|YP_281105.1| 23S rRNA methyltransferase [Streptococcus pyogenes MGAS6180]; tRNA/rRNA methyltransferase 1807620 6761830 Sez_1751 Streptococcus equi subsp. zooepidemicus MGCS10565 tRNA/rRNA methyltransferase YP_002124091.1 1806874 R 552526 CDS YP_002124092.1 195978848 6761828 complement(1807669..1808466) 1 NC_011134.1 similar to ref|YP_599330.1| hypothetical membrane associated protein [Streptococcus pyogenes MGAS10270]; hypothetical protein 1808466 6761828 Sez_1752 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002124092.1 1807669 R 552526 CDS YP_002124093.1 195978849 6761825 complement(1808683..1809090) 1 NC_011134.1 similar to ref|ZP_00366252.1| COG1939: Uncharacterized protein conserved in bacteria [Streptococcus pyogenes M49 591]; similar to cysteinyl-tRNA synthetase; hypothetical protein 1809090 6761825 Sez_1753 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002124093.1 1808683 R 552526 CDS YP_002124094.1 195978850 6761819 complement(1809083..1810429) 1 NC_011134.1 catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA; cysteinyl-tRNA synthetase 1810429 cysS 6761819 cysS Streptococcus equi subsp. zooepidemicus MGCS10565 cysteinyl-tRNA synthetase YP_002124094.1 1809083 R 552526 CDS YP_002124095.1 195978851 6761795 complement(1810548..1811084) 1 NC_011134.1 similar to ref|YP_599335.1| serineacetyltransferase [Streptococcus pyogenes MGAS10270]; Cysteine biosynthesis.; serine acetyltransferase CysE 1811084 cysE 6761795 cysE Streptococcus equi subsp. zooepidemicus MGCS10565 serine acetyltransferase CysE YP_002124095.1 1810548 R 552526 CDS YP_002124096.1 195978852 6761789 complement(1811096..1811848) 1 NC_011134.1 similar to ref|YP_001129151.1| hypothetical protein SpyM51632 [Streptococcus pyogenes str. Manfredo]; hypothetical protein 1811848 6761789 Sez_1756 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002124096.1 1811096 R 552526 CDS YP_002124097.1 195978853 6761785 complement(1811841..1813985) 1 NC_011134.1 similar to ref|YP_281113.1| polynucleotide phosphorylase/polyadenylase [Streptococcus pyogenes MGAS6180]; Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction. Necessary for competence development in Bacillus subtilis. May be necessary for modification of the srfA transcript (stabilization or translation activation).; polynucleotide phosphorylase 1813985 pnpA 6761785 pnpA Streptococcus equi subsp. zooepidemicus MGCS10565 polynucleotide phosphorylase YP_002124097.1 1811841 R 552526 CDS YP_002124098.1 195978854 6761716 complement(1814354..1814623) 1 NC_011134.1 primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence; 30S ribosomal protein S15 1814623 rpsO 6761716 rpsO Streptococcus equi subsp. zooepidemicus MGCS10565 30S ribosomal protein S15 YP_002124098.1 1814354 R 552526 CDS YP_002124099.1 195978855 6761776 complement(1814889..1816337) 1 NC_011134.1 similar to dbj|BAD00708.1| fibronectin-binding protein [Streptococcus equi subsp. zooepidemicus]; The ability of bacteria to bind fibronectin has been proposed as a virulence factor enabling bacteria to colonize wound tissues and blood clots. Binding of plasma fibronectin to the bacterial surface might block adhesion receptors on S.aureus, thus representing an important defense mechanism against tissue invasion.; fibronectin-binding protein precursor Fnz2 1816337 fnz2 6761776 fnz2 Streptococcus equi subsp. zooepidemicus MGCS10565 fibronectin-binding protein precursor Fnz2 YP_002124099.1 1814889 R 552526 CDS YP_002124100.1 195978856 6761771 1816708..1817322 1 NC_011134.1 cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+); peptide deformylase 1817322 def 6761771 def Streptococcus equi subsp. zooepidemicus MGCS10565 peptide deformylase YP_002124100.1 1816708 D 552526 CDS YP_002124101.1 195978857 6761793 complement(1817449..1818030) 1 NC_011134.1 similar to ref|YP_283033.1| oxidoreductase [Streptococcus pyogenes MGAS5005]; hypothetical protein 1818030 6761793 Sez_1761 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002124101.1 1817449 R 552526 CDS YP_002124102.1 195978858 6761761 complement(1818124..1818552) 1 NC_011134.1 similar to ref|YP_060997.1| Transcriptional regulator, MarR family [Streptococcus pyogenes MGAS10394]; Transcriptional Regulation; MarR family transcriptional regulator 1818552 6761761 Sez_1762 Streptococcus equi subsp. zooepidemicus MGCS10565 MarR family transcriptional regulator YP_002124102.1 1818124 R 552526 CDS YP_002124103.1 195978859 6761759 complement(1818674..1823071) 1 NC_011134.1 catalyzes DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time; required for leading strand synthesis; PolC exhibits 3' to 5' exonuclease activity; DNA polymerase III PolC 1823071 polC 6761759 polC Streptococcus equi subsp. zooepidemicus MGCS10565 DNA polymerase III PolC YP_002124103.1 1818674 R 552526 CDS YP_002124104.1 195978860 6761758 complement(1823406..1823963) 1 NC_011134.1 similar to ref|NP_720759.1| hypothetical protein SMU.301 [Streptococcus mutans UA159]; hypothetical protein 1823963 6761758 Sez_1764 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002124104.1 1823406 R 552526 CDS YP_002124105.1 195978861 6761769 complement(1824015..1825856) 1 NC_011134.1 catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro); prolyl-tRNA synthetase 1825856 proS 6761769 proS Streptococcus equi subsp. zooepidemicus MGCS10565 prolyl-tRNA synthetase YP_002124105.1 1824015 R 552526 CDS YP_002124106.1 195978862 6761768 complement(1826141..1827406) 1 NC_011134.1 similar to ref|YP_281127.1| pheromone-processing membrane metalloprotease [Streptococcus pyogenes MGAS6180]; zinc metalloprotease 1827406 6761768 Sez_1766 Streptococcus equi subsp. zooepidemicus MGCS10565 zinc metalloprotease YP_002124106.1 1826141 R 552526 CDS YP_002124107.1 195978863 6761753 complement(1827438..1828232) 1 NC_011134.1 similar to ref|ZP_00365468.1| COG0575: CDP-diglyceride synthetase [Streptococcus pyogenes M49 591]; Catalysis of the reaction: CTP + phosphatidate = diphosphate + CDP-diacylglycerol.; phosphatidate cytidylyltransferase 1828232 cdsA 6761753 cdsA Streptococcus equi subsp. zooepidemicus MGCS10565 phosphatidate cytidylyltransferase YP_002124107.1 1827438 R 552526 CDS YP_002124108.1 195978864 6761762 complement(1828242..1828991) 1 NC_011134.1 catalyzes the formation of UDP pyrophosphate from isopentenyl pyrophosphate; UDP pyrophosphate synthase 1828991 uppS 6761762 uppS Streptococcus equi subsp. zooepidemicus MGCS10565 UDP pyrophosphate synthase YP_002124108.1 1828242 R 552526 CDS YP_002124109.1 195978865 6761731 complement(1829165..1829524) 1 NC_011134.1 member of preprotein translocase; forms a heterotrimer with SecD and SecF; links the SecD/SecF/YajC/YidC complex with the SecY/SecE/SecG complex; preprotein translocase subunit YajC 1829524 yajC 6761731 yajC Streptococcus equi subsp. zooepidemicus MGCS10565 preprotein translocase subunit YajC YP_002124109.1 1829165 R 552526 CDS YP_002124110.1 195978866 6761744 complement(1829638..1830000) 1 NC_011134.1 similar to ref|YP_061004.1| Thioredoxin [Streptococcus pyogenes MGAS10394]; transport accessory protein 1830000 6761744 Sez_1770 Streptococcus equi subsp. zooepidemicus MGCS10565 transport accessory protein YP_002124110.1 1829638 R 552526 CDS YP_002124111.1 195978867 6761713 complement(1830109..1831731) 1 NC_011134.1 similar to ref|YP_283044.1| glucan 1,6-alpha-glucosidase [Streptococcus pyogenes MGAS5005]; The physiological substrates may be short isomaltosaccharides.; glucan 1,6-alpha-glucosidase 1831731 dexB 6761713 dexB Streptococcus equi subsp. zooepidemicus MGCS10565 glucan 1,6-alpha-glucosidase YP_002124111.1 1830109 R 552526 CDS YP_002124112.1 195978868 6761740 complement(1831912..1833045) 1 NC_011134.1 similar to ref|NP_269942.1| multiple sugar-binding ABC transport system (ATP-binding protein) [Streptococcus pyogenes M1 GAS]; Involved in a binding protein-dependent transport system responsible for the uptake of melibiose, raffinose and isomaltotriose. Probably responsible for energy coupling to the transport system.; multiple sugar-binding transport ATP-binding protein 1833045 6761740 Sez_1772 Streptococcus equi subsp. zooepidemicus MGCS10565 multiple sugar-binding transport ATP-binding protein YP_002124112.1 1831912 R 552526 CDS YP_002124113.1 195978869 6761734 complement(1833196..1834044) 1 NC_011134.1 similar to emb|CAA51350.1| leucine rich protein [Streptococcus dysgalactiae subsp. equisimilis]; hypothetical protein 1834044 lrp 6761734 lrp Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002124113.1 1833196 R 552526 CDS YP_002124114.1 195978870 6761708 complement(1834339..1834515) 1 NC_011134.1 hypothetical protein 1834515 6761708 Sez_1774 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002124114.1 1834339 R 552526 CDS YP_002124115.1 195978871 6761709 1834799..1836073 1 NC_011134.1 similar to gb|AAC83933.1| streptokinase precursor [Streptococcus dysgalactiae subsp. equisimilis]; streptokinase plasminogen activator Skc 1836073 skc 6761709 skc Streptococcus equi subsp. zooepidemicus MGCS10565 streptokinase plasminogen activator Skc YP_002124115.1 1834799 D 552526 CDS YP_002124116.1 195978872 6761706 complement(1836198..1836641) 1 NC_011134.1 hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr); possible defense mechanism against a harmful effect of D-tyrosine; D-tyrosyl-tRNA(Tyr) deacylase 1836641 dtd 6761706 dtd Streptococcus equi subsp. zooepidemicus MGCS10565 D-tyrosyl-tRNA(Tyr) deacylase YP_002124116.1 1836198 R 552526 CDS YP_002124117.1 195978873 6761699 complement(1836656..1838875) 1 NC_011134.1 similar to ref|NP_608020.1| (p)ppGpp synthetase [Streptococcus pyogenes MGAS8232]; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. This enzyme catalyzes the formation of pppGpp which is then hydrolyzed to form ppGpp.; GTP pyrophosphokinase 1838875 relA 6761699 relA Streptococcus equi subsp. zooepidemicus MGCS10565 GTP pyrophosphokinase YP_002124117.1 1836656 R 552526 CDS YP_002124118.1 195978874 6761692 complement(1839093..1840310) 1 NC_011134.1 similar to gb|AAD42939.2|AF086813_1 protective antigen [Streptococcus pyogenes]; protective antigen SpaZ 1840310 spaZ 6761692 spaZ Streptococcus equi subsp. zooepidemicus MGCS10565 protective antigen SpaZ YP_002124118.1 1839093 R 552526 CDS YP_002124119.1 195978875 6761669 1840558..1841742 1 NC_011134.1 similar to ref|NP_608022.1| transcriptional regulator [Streptococcus pyogenes MGAS8232]; AraC family transcriptional regulator 1841742 6761669 Sez_1779 Streptococcus equi subsp. zooepidemicus MGCS10565 AraC family transcriptional regulator YP_002124119.1 1840558 D 552526 CDS YP_002124120.1 195978876 6761663 1841951..1842409 1 NC_011134.1 has a stimulatory effect on the ribonucleotide reductase activity of NrdH with NrdEF; flavoprotein NrdI 1842409 nrdI 6761663 nrdI Streptococcus equi subsp. zooepidemicus MGCS10565 flavoprotein NrdI YP_002124120.1 1841951 D 552526 CDS YP_002124121.1 195978877 6761685 complement(1842590..1842736) 1 NC_011134.1 hypothetical protein 1842736 6761685 Sez_1781 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002124121.1 1842590 R 552526 CDS YP_002124122.1 195978878 6761676 complement(1842714..1843535) 1 NC_011134.1 similar to ref|NP_608024.1| hypothetical protein spyM18_2049 [Streptococcus pyogenes MGAS8232]; Catalysis of the degradation of double-stranded DNA. It acts progressively in a 3' to 5' direction, releasing 5'-phosphomononucleotides.; exodeoxyribonuclease III 1843535 6761676 Sez_1782 Streptococcus equi subsp. zooepidemicus MGCS10565 exodeoxyribonuclease III YP_002124122.1 1842714 R 552526 CDS YP_002124123.1 195978879 6761648 complement(1843613..1845799) 1 NC_011134.1 similar to ref|YP_603278.1| PTS system, glucose-specific IIABC component [Streptococcus pyogenes MGAS10750]; The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active-transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. This system is involved in glucose transport.; PTS system glucose-specific transporter subunit IICBA 1845799 6761648 Sez_1783 Streptococcus equi subsp. zooepidemicus MGCS10565 PTS system glucose-specific transporter subunit IICBA YP_002124123.1 1843613 R 552526 CDS YP_002124124.1 195978880 6761665 complement(1846097..1847119) 1 NC_011134.1 similar to ref|NP_784004.1| transcription regulator [Lactobacillus plantarum WCFS1]; HTH-type transcriptional regulator MalR-like 1847119 6761665 Sez_1784 Streptococcus equi subsp. zooepidemicus MGCS10565 HTH-type transcriptional regulator MalR-like YP_002124124.1 1846097 R 552526 CDS YP_002124125.1 195978881 6761661 complement(1847222..1848259) 1 NC_011134.1 similar to ref|YP_001200768.1| Predicted transcriptional regulator [Streptococcus suis 98HAH33]; hypothetical protein 1848259 6761661 Sez_1785 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002124125.1 1847222 R 552526 CDS YP_002124126.1 195978882 6761639 complement(1848279..1849448) 1 NC_011134.1 similar to ref|YP_001198563.1| lantibiotic efflux protein [Streptococcus suis 05ZYH33]; hypothetical protein 1849448 6761639 Sez_1786 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002124126.1 1848279 R 552526 CDS YP_002124127.1 195978883 6761649 complement(1849623..1849760) 1 NC_011134.1 hypothetical protein 1849760 6761649 Sez_1787 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002124127.1 1849623 R 552526 CDS YP_002124128.1 195978884 6761647 complement(1849868..1850614) 1 NC_011134.1 in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA; cells lacking this function can grow, but are outcompeted by wild-type; SAM-dependent m(3)U1498 methyltransferase; 16S ribosomal RNA methyltransferase RsmE 1850614 6761647 Sez_1788 Streptococcus equi subsp. zooepidemicus MGCS10565 16S ribosomal RNA methyltransferase RsmE YP_002124128.1 1849868 R 552526 CDS YP_002124129.1 195978885 6761643 complement(1850614..1851567) 1 NC_011134.1 methylates ribosomal protein L11 at multiple amino acid positions; mutations of these genes in Escherichia coli or Thermus thermophilus has no apparent phenotype; 50S ribosomal protein L11 methyltransferase 1851567 prmA 6761643 prmA Streptococcus equi subsp. zooepidemicus MGCS10565 50S ribosomal protein L11 methyltransferase YP_002124129.1 1850614 R 552526 CDS YP_002124130.1 195978886 6761638 1852127..1854670 1 NC_011134.1 similar to ref|ZP_00874737.1| Streptococcal histidine triad [Streptococcus suis 89/1591]; internalin A-like histidine triad lipoprotein 1854670 6761638 Sez_1790 Streptococcus equi subsp. zooepidemicus MGCS10565 internalin A-like histidine triad lipoprotein YP_002124130.1 1852127 D 552526 CDS YP_002124131.1 195978887 6761637 complement(1854868..1855296) 1 NC_011134.1 similar to ref|ZP_01817507.1| MutT/nudix family protein [Streptococcus pneumoniae SP3-BS71]; MutT/nudix family protein 1855296 6761637 Sez_1791 Streptococcus equi subsp. zooepidemicus MGCS10565 MutT/nudix family protein YP_002124131.1 1854868 R 552526 CDS YP_002124132.1 195978888 6761612 complement(1855316..1855657) 1 NC_011134.1 similar to ref|ZP_00366058.1| COG4043: Uncharacterized conserved protein [Streptococcus pyogenes M49 591]; hypothetical protein 1855657 6761612 Sez_1792 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002124132.1 1855316 R 552526 CDS YP_002124133.1 195978889 6761634 complement(1855659..1856129) 1 NC_011134.1 similar to ref|YP_001129182.1| hypothetical protein SpyM51665 [Streptococcus pyogenes str. Manfredo]; hypothetical protein 1856129 6761634 Sez_1793 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002124133.1 1855659 R 552526 CDS YP_002124134.1 195978890 6761604 1856283..1858019 1 NC_011134.1 similar to ref|YP_061021.1| 4-amino-4-deoxychorismate lyase [Streptococcus pyogenes MGAS10394]; Catalyzes the biosynthesis of 4-amino-4-deoxychorismate (ADC) from chorismate and glutamine.; para-aminobenzoate synthase PabA 1858019 pabA 6761604 pabA Streptococcus equi subsp. zooepidemicus MGCS10565 para-aminobenzoate synthase PabA YP_002124134.1 1856283 D 552526 CDS YP_002124135.1 195978891 6761629 1858048..1858668 1 NC_011134.1 TrpG; with TrpE catalyzes the formation of anthranilate and glutamate from chorismate and glutamine; TrpG provides the glutamine amidotransferase activity; anthranilate synthase component II 1858668 pabB 6761629 pabB Streptococcus equi subsp. zooepidemicus MGCS10565 anthranilate synthase component II YP_002124135.1 1858048 D 552526 CDS YP_002124136.1 195978892 6761626 1858661..1859932 1 NC_011134.1 similar to ref|YP_061023.1| recombination factor protein RarA [Streptococcus pyogenes MGAS10394]; ATPase related to the helicase subunit of the Holliday junction resolvase [DNA replication, recombination, and repair]; COG2256.; recombination factor protein RarA 1859932 rarA 6761626 rarA Streptococcus equi subsp. zooepidemicus MGCS10565 recombination factor protein RarA YP_002124136.1 1858661 D 552526 CDS YP_002124137.1 195978893 6761142 1860513..1861082 1 NC_011134.1 hypothetical protein 1861082 6761142 Sez_1797 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002124137.1 1860513 D 552526 CDS YP_002124138.1 195978894 6762215 1861193..1862053 1 NC_011134.1 similar to ref|ZP_01825592.1| transcriptional activator, Rgg/GadR/MutR family protein, C-terminal domain [Streptococcus pneumoniae SP11-BS70]; Transcriptional regulator; positive transcriptional regulator MutR family 1862053 6762215 Sez_1798 Streptococcus equi subsp. zooepidemicus MGCS10565 positive transcriptional regulator MutR family YP_002124138.1 1861193 D 552526 CDS YP_002124139.1 195978895 6762211 1862313..1862534 1 NC_011134.1 hypothetical protein 1862534 6762211 Sez_1799 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002124139.1 1862313 D 552526 CDS YP_002124140.1 195978896 6762186 1862515..1863411 1 NC_011134.1 similar to ref|YP_820672.1| Permease of the major facilitator superfamily [Streptococcus thermophilus LMD-9]; permease 1863411 6762186 Sez_1800 Streptococcus equi subsp. zooepidemicus MGCS10565 permease YP_002124140.1 1862515 D 552526 CDS YP_002124141.1 195978897 6762208 1864067..1864582 1 NC_011134.1 similar to ref|YP_281151.1| topology modulation protein [Streptococcus pyogenes MGAS6180]; topology modulation protein 1864582 6762208 Sez_1801 Streptococcus equi subsp. zooepidemicus MGCS10565 topology modulation protein YP_002124141.1 1864067 D 552526 CDS YP_002124142.1 195978898 6762182 1866077..1867450 1 NC_011134.1 similar to ref|YP_329518.1| cell wall surface anchor family protein [Streptococcus agalactiae A909]; Has domains with similarity to different streptococal surface proteins such as M protein, internalin, and histidine triad proteins.; Emm-like cell surface protein CspZ.1 1867450 cspZ.1 6762182 cspZ.1 Streptococcus equi subsp. zooepidemicus MGCS10565 Emm-like cell surface protein CspZ.1 YP_002124142.1 1866077 D 552526 CDS YP_002124143.1 195978899 6761811 complement(1867686..1868765) 1 NC_011134.1 similar to gb|AAQ91578.1| collagen-like protein 3 [Streptococcus equi]; Possible adhesin, has a collagen-structural-motif domain composed of 60 Gly-Xaa-Yaa repeats.; hypothetical protein 1868765 sclZ.12 6761811 sclZ.12 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002124143.1 1867686 R 552526 CDS YP_002124144.1 195978900 6761864 complement(1868964..1869533) 1 NC_011134.1 similar to ref|YP_001037859.1| Phosphoglycerate mutase [Clostridium thermocellum ATCC 27405]; phosphoglycerate mutase family protein 1869533 6761864 Sez_1804 Streptococcus equi subsp. zooepidemicus MGCS10565 phosphoglycerate mutase family protein YP_002124144.1 1868964 R 552526 CDS YP_002124145.1 195978901 6761858 complement(1869535..1870617) 1 NC_011134.1 similar to ref|YP_815692.1| MccC family protein [Streptococcus pneumoniae D39]; microcin self-immunity protein 1870617 6761858 Sez_1805 Streptococcus equi subsp. zooepidemicus MGCS10565 microcin self-immunity protein YP_002124145.1 1869535 R 552526 CDS YP_002124146.1 195978902 6761841 complement(1871123..1872214) 1 NC_011134.1 forms dimers and octamers; involved in conversion of glycerol to dihydroxy-acetone; glycerol dehydrogenase 1872214 gldA 6761841 gldA Streptococcus equi subsp. zooepidemicus MGCS10565 glycerol dehydrogenase YP_002124146.1 1871123 R 552526 CDS YP_002124147.1 195978903 6761837 complement(1872339..1873007) 1 NC_011134.1 similar to transaldolase from Escherichia coli; many organisms have multiple copies; fructose-6-phosphate aldolase 1873007 fsa 6761837 fsa Streptococcus equi subsp. zooepidemicus MGCS10565 fructose-6-phosphate aldolase YP_002124147.1 1872339 R 552526 CDS YP_002124148.1 195978904 6761836 complement(1873022..1875439) 1 NC_011134.1 similar to ref|YP_281195.1| formate acetyltransferase [Streptococcus pyogenes MGAS6180]; Catalysis of the reaction: acetyl-CoA + formate = CoA + pyruvate.; pyruvate formate-lyase 1875439 6761836 Sez_1808 Streptococcus equi subsp. zooepidemicus MGCS10565 pyruvate formate-lyase YP_002124148.1 1873022 R 552526 CDS YP_002124149.1 195978905 6761812 complement(1875720..1877024) 1 NC_011134.1 similar to ref|YP_603332.1| PTS system, cellobiose-specific IIC component [Streptococcus pyogenes MGAS10750]; The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. This system is involved in cellobiose transport.; cellobiose permease IIC component CelC 1877024 celC 6761812 celC Streptococcus equi subsp. zooepidemicus MGCS10565 cellobiose permease IIC component CelC YP_002124149.1 1875720 R 552526 CDS YP_002124150.1 195978906 6761829 complement(1877035..1877343) 1 NC_011134.1 similar to ref|YP_603333.1| PTS system, cellobiose-specific IIB component [Streptococcus pyogenes MGAS10750]; The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. This system is involved in cellobiose transport.; cellobiose-specific phosphotransferase enzyme IIB component CelB 1877343 celB 6761829 celB Streptococcus equi subsp. zooepidemicus MGCS10565 cellobiose-specific phosphotransferase enzyme IIB component CelB YP_002124150.1 1877035 R 552526 CDS YP_002124151.1 195978907 6761827 complement(1877368..1877688) 1 NC_011134.1 similar to ref|YP_283109.1| PTS system, cellobiose-specific IIA component [Streptococcus pyogenes MGAS5005]; The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. This system is involved in cellobiose transport.; PTS system cellobiose-specific transporter subunit IIA CelA 1877688 celA 6761827 celA Streptococcus equi subsp. zooepidemicus MGCS10565 PTS system cellobiose-specific transporter subunit IIA CelA YP_002124151.1 1877368 R 552526 CDS YP_002124152.1 195978908 6761824 complement(1877722..1877847) 1 NC_011134.1 hypothetical protein 1877847 6761824 Sez_1812 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002124152.1 1877722 R 552526 CDS YP_002124153.1 195978909 6761816 complement(1877927..1878907) 1 NC_011134.1 similar to ref|NP_269997.1| transcriptional regulator [Streptococcus pyogenes M1 GAS]; transcriptional regulator 1878907 6761816 Sez_1813 Streptococcus equi subsp. zooepidemicus MGCS10565 transcriptional regulator YP_002124153.1 1877927 R 552526 CDS YP_002124154.1 195978910 6761807 complement(1878922..1879668) 1 NC_011134.1 similar to ref|ZP_00365881.1| COG1349: Transcriptional regulators of sugar metabolism [Streptococcus pyogenes M49 591]; HTH-type transcriptional regulator 1879668 6761807 Sez_1814 Streptococcus equi subsp. zooepidemicus MGCS10565 HTH-type transcriptional regulator YP_002124154.1 1878922 R 552526 CDS YP_002124155.1 195978911 6761800 1879697..1880566 1 NC_011134.1 similar to ref|NP_608074.1| pyruvate formate-lyase activating enzyme [Streptococcus pyogenes MGAS8232]; Activation of pyruvate formate-lyase 2 under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.; pyruvate formate-lyase activating enzyme 1880566 6761800 Sez_1815 Streptococcus equi subsp. zooepidemicus MGCS10565 pyruvate formate-lyase activating enzyme YP_002124155.1 1879697 D 552526 CDS YP_002124156.1 195978912 6761802 complement(1880679..1881995) 1 NC_011134.1 catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis; adenylosuccinate synthetase 1881995 purA 6761802 purA Streptococcus equi subsp. zooepidemicus MGCS10565 adenylosuccinate synthetase YP_002124156.1 1880679 R 552526 CDS YP_002124157.1 195978913 6761780 1882028..1882213 1 NC_011134.1 hypothetical protein 1882213 6761780 Sez_1817 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002124157.1 1882028 D 552526 CDS YP_002124158.1 195978914 6761796 1882314..1883171 1 NC_011134.1 similar to ref|NP_606463.1| hypothetical protein spyM18_0155 [Streptococcus pyogenes MGAS8232]; hypothetical protein 1883171 6761796 Sez_1818 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002124158.1 1882314 D 552526 CDS YP_002124159.1 195978915 6761770 1883186..1884451 1 NC_011134.1 similar to ref|NP_606462.1| toxic anion resistance protein [Streptococcus pyogenes MGAS8232]; toxic anion resistance protein 1884451 6761770 Sez_1819 Streptococcus equi subsp. zooepidemicus MGCS10565 toxic anion resistance protein YP_002124159.1 1883186 D 552526 CDS YP_002124160.1 195978916 6761792 complement(1884627..1885475) 1 NC_011134.1 similar to ref|YP_279575.1| sortase [Streptococcus pyogenes MGAS6180]; Fimbrial associated sortase required for subunit polymerization.; sortase 1885475 srtC.2 6761792 srtC.2 Streptococcus equi subsp. zooepidemicus MGCS10565 sortase YP_002124160.1 1884627 R 552526 CDS YP_002124161.1 195978917 6761784 complement(1885553..1887202) 1 NC_011134.1 similar to gb|AAZ82124.1| fimbrial structural subunit [Streptococcus pyogenes serotype M23]; Fimbrial structural subunit involved in adhesion.; T-antigen-like fimbrial structural subunit protein FszC 1887202 fszC 6761784 fszC Streptococcus equi subsp. zooepidemicus MGCS10565 T-antigen-like fimbrial structural subunit protein FszC YP_002124161.1 1885553 R 552526 CDS YP_002124162.1 195978918 6761778 complement(1887239..1890142) 1 NC_011134.1 similar to ref|YP_059477.1| Collagen adhesion protein [Streptococcus pyogenes MGAS10394]; Fimbrial component, has a centrally located Von Willebrand factor A domain and a carboxy end located Cna protein B-type domain.; fimbrial structural subunit protein FszD 1890142 fszD 6761778 fszD Streptococcus equi subsp. zooepidemicus MGCS10565 fimbrial structural subunit protein FszD YP_002124162.1 1887239 R 552526 CDS YP_002124163.1 195978919 6761735 1890417..1891919 1 NC_011134.1 similar to ref|ZP_00782298.1| transcription regulator, , [Streptococcus agalactiae H36B]; Regulation of fimbrial gene transcription.; RofA/Nra-like transcriptional regulator 1891919 6761735 Sez_1823 Streptococcus equi subsp. zooepidemicus MGCS10565 RofA/Nra-like transcriptional regulator YP_002124163.1 1890417 D 552526 CDS YP_002124164.1 195978920 6761756 complement(1891943..1892074) 1 NC_011134.1 hypothetical protein 1892074 6761756 Sez_1824 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002124164.1 1891943 R 552526 CDS YP_002124165.1 195978921 6761766 complement(1892313..1894811) 1 NC_011134.1 similar to ref|YP_597726.1| Fibronectin-binding protein [Streptococcus pyogenes MGAS10270]; fibronectin-binding protein FbpZ 1894811 fbpZ 6761766 fbpZ Streptococcus equi subsp. zooepidemicus MGCS10565 fibronectin-binding protein FbpZ YP_002124165.1 1892313 R 552526 CDS YP_002124166.1 195978922 6761746 complement(1894872..1895696) 1 NC_011134.1 similar to ref|YP_597725.1| Sortase [Streptococcus pyogenes MGAS10270]; Fimbrial associated dedicated sortase required for subunit polymerization.; sortase 1895696 srtC.3 6761746 srtC.3 Streptococcus equi subsp. zooepidemicus MGCS10565 sortase YP_002124166.1 1894872 R 552526 CDS YP_002124167.1 195978923 6761736 complement(1895711..1896541) 1 NC_011134.1 similar to ref|YP_597720.1| Sortase [Streptococcus pyogenes MGAS10270]; Fimbrial associated dedicated sortase required for subunit polymerization.; sortase 1896541 srtC.4 6761736 srtC.4 Streptococcus equi subsp. zooepidemicus MGCS10565 sortase YP_002124167.1 1895711 R 552526 CDS YP_002124168.1 195978924 6761727 complement(1896591..1897505) 1 NC_011134.1 similar to ref|YP_597719.1| hypothetical protein MGAS10270_Spy0110 [Streptococcus pyogenes MGAS10270]; Fimbrial subunit protein, has a Cna B-type domain.; T-antigen-like fimbrial structural subunit protein FszE 1897505 fszE 6761727 fszE Streptococcus equi subsp. zooepidemicus MGCS10565 T-antigen-like fimbrial structural subunit protein FszE YP_002124168.1 1896591 R 552526 CDS YP_002124169.1 195978925 6761714 complement(1897630..1899480) 1 NC_011134.1 similar to ref|YP_597718.1| hypothetical protein MGAS10270_Spy0109 [Streptococcus pyogenes MGAS10270]; Fimbrial structural subunit protein.; fimbrial subunit protein FszF 1899480 fszF 6761714 fszF Streptococcus equi subsp. zooepidemicus MGCS10565 fimbrial subunit protein FszF YP_002124169.1 1897630 R 552526 CDS YP_002124170.1 195978926 6761739 1899760..1901022 1 NC_011134.1 similar to ref|ZP_00784533.1| transcriptional regulator, AraC family [Streptococcus agalactiae COH1]; AraC family transcriptional regulator 1901022 6761739 Sez_1830 Streptococcus equi subsp. zooepidemicus MGCS10565 AraC family transcriptional regulator YP_002124170.1 1899760 D 552526 CDS YP_002124171.1 195978927 6761711 complement(1901106..1901240) 1 NC_011134.1 hypothetical protein 1901240 6761711 Sez_1831 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002124171.1 1901106 R 552526 CDS YP_002124172.1 195978928 6761730 1901272..1902144 1 NC_011134.1 becomes active under oxidative stress; four conserved cysteines bind a zinc atom when they are in the reduced state and the enzyme is inactive; oxidative stress results in oxidized cysteines, release of zinc, and binding of Hsp33 to aggregation-prone proteins; forms dimers and higher order oligomers; heat shock protein 33 1902144 hslO 6761730 hslO Streptococcus equi subsp. zooepidemicus MGCS10565 heat shock protein 33 YP_002124172.1 1901272 D 552526 CDS YP_002124173.1 195978929 6761726 1902167..1903108 1 NC_011134.1 similar to ref|YP_595837.1| tRNA-dihydrouridine synthase [Streptococcus pyogenes MGAS9429]; Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs.; tRNA-dihydrouridine synthase Dus 1903108 dus 6761726 dus Streptococcus equi subsp. zooepidemicus MGCS10565 tRNA-dihydrouridine synthase Dus YP_002124173.1 1902167 D 552526 CDS YP_002124174.1 195978930 6761707 1903129..1903770 1 NC_011134.1 similar to dbj|BAB16044.1| similar to Lactobacillus acidophilus dA/dG-kinase [Streptococcus equi subsp. zooepidemicus]; DGK/DAK plays an essential role in generating the deoxyribonucleotide precursors, dGTP and dATP, for DNA metabolism.; deoxyguanosine kinase 1903770 6761707 Sez_1834 Streptococcus equi subsp. zooepidemicus MGCS10565 deoxyguanosine kinase YP_002124174.1 1903129 D 552526 CDS YP_002124175.1 195978931 6761691 1904052..1905056 1 NC_011134.1 similar to ref|NP_687848.1| hypothetical protein SAG0833 [Streptococcus agalactiae 2603V/R]; hypothetical protein 1905056 6761691 Sez_1835 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002124175.1 1904052 D 552526 CDS YP_002124176.1 195978932 6761673 complement(1905107..1905910) 1 NC_011134.1 similar to ref|YP_001198619.1| ABC-type uncharacterized transport system, ATPase component [Streptococcus suis 05ZYH33]; Part of the ABC transporter complex. Responsible for energy coupling to the transport system.; ABC transporter ATP-binding protein 1905910 6761673 Sez_1836 Streptococcus equi subsp. zooepidemicus MGCS10565 ABC transporter ATP-binding protein YP_002124176.1 1905107 R 552526 CDS YP_002124177.1 195978933 6761580 complement(1905919..1906803) 1 NC_011134.1 similar to ref|YP_001200827.1| ABC-type uncharacterized transport system, permease component [Streptococcus suis 98HAH33]; Part of the binding-protein-dependent transport system. Probably responsible for the translocation of the substrate across the membrane.; ABC transporter permease 1906803 6761580 Sez_1837 Streptococcus equi subsp. zooepidemicus MGCS10565 ABC transporter permease YP_002124177.1 1905919 R 552526 CDS YP_002124178.1 195978934 6761666 complement(1906913..1907875) 1 NC_011134.1 similar to ref|YP_001200828.1| hypothetical protein SSU98_1270 [Streptococcus suis 98HAH33]; ABC transporter substrate-binding.; ABC transporter substrate-binding lipoprotein 1907875 6761666 Sez_1838 Streptococcus equi subsp. zooepidemicus MGCS10565 ABC transporter substrate-binding lipoprotein YP_002124178.1 1906913 R 552526 CDS YP_002124179.1 195978935 6761662 complement(1907902..1908888) 1 NC_011134.1 similar to ref|YP_001200829.1| ABC transporter permease [Streptococcus suis 98HAH33]; substrate-binding for ABC transport system.; ABC transporter substrate-binding lipoprotein 1908888 6761662 Sez_1839 Streptococcus equi subsp. zooepidemicus MGCS10565 ABC transporter substrate-binding lipoprotein YP_002124179.1 1907902 R 552526 CDS YP_002124180.1 195978936 6761684 complement(1909273..1910226) 1 NC_011134.1 similar to ref|YP_138591.1| IS1239 transposase [Streptococcus thermophilus LMG 18311]; transposase IS1239 1910226 6761684 Sez_1840 Streptococcus equi subsp. zooepidemicus MGCS10565 transposase IS1239 YP_002124180.1 1909273 R 552526 CDS YP_002124181.1 195978937 6761644 complement(1911977..1912372) 1 NC_011134.1 binds to single stranded DNA and may facilitate the binding and interaction of other proteins to DNA; single-stranded DNA-binding protein 1912372 ssb 6761644 ssb Streptococcus equi subsp. zooepidemicus MGCS10565 single-stranded DNA-binding protein YP_002124181.1 1911977 R 552526 CDS YP_002124182.1 195978938 6761664 1912426..1913196 1 NC_011134.1 similar to ref|ZP_00784652.1| conserved hypothetical protein [Streptococcus agalactiae COH1]; S-adenosylmethionine-dependent methyltransferase 1913196 6761664 Sez_1845 Streptococcus equi subsp. zooepidemicus MGCS10565 S-adenosylmethionine-dependent methyltransferase YP_002124182.1 1912426 D 552526 CDS YP_002124183.1 195978939 6761659 complement(1913498..1914124) 1 NC_011134.1 similar to ref|YP_059468.1| tRNA binding domain protein [Streptococcus pyogenes MGAS10394]; tRNA binding domain-containing protein 1914124 6761659 Sez_1846 Streptococcus equi subsp. zooepidemicus MGCS10565 tRNA binding domain-containing protein YP_002124183.1 1913498 R 552526 CDS YP_002124184.1 195978940 6761650 complement(1914139..1914456) 1 NC_011134.1 similar to ref|YP_059467.1| Thioredoxin [Streptococcus pyogenes MGAS10394]; Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions.; thioredoxin 1914456 trxA 6761650 trxA Streptococcus equi subsp. zooepidemicus MGCS10565 thioredoxin YP_002124184.1 1914139 R 552526 CDS YP_002124185.1 195978941 6761632 complement(1914453..1914800) 1 NC_011134.1 similar to ref|NP_801354.1| hypothetical protein SPs0092 [Streptococcus pyogenes SSI-1]; hypothetical protein 1914800 6761632 Sez_1848 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002124185.1 1914453 R 552526 CDS YP_002124186.1 195978942 6761646 1915141..1916208 1 NC_011134.1 similar to ref|YP_595830.1| glutamyl aminopeptidase [Streptococcus pyogenes MGAS9429]; Release of N-terminal glutamate (and to a lesser extent aspartate) from a peptide.; glutamyl aminopeptidase PepA 1916208 pepA 6761646 pepA Streptococcus equi subsp. zooepidemicus MGCS10565 glutamyl aminopeptidase PepA YP_002124186.1 1915141 D 552526 CDS YP_002124187.1 195978943 6761640 1916292..1917065 1 NC_011134.1 catalyzes the formation of L-proline from pyrroline-5-carboxylate; pyrroline-5-carboxylate reductase 1917065 proC 6761640 proC Streptococcus equi subsp. zooepidemicus MGCS10565 pyrroline-5-carboxylate reductase YP_002124187.1 1916292 D 552526 CDS YP_002124188.1 195978944 6761618 complement(1917300..1917737) 1 NC_011134.1 similar to ref|NP_268507.1| hypothetical protein SPy_0110 [Streptococcus pyogenes M1 GAS]; hypothetical protein 1917737 6761618 Sez_1851 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002124188.1 1917300 R 552526 CDS YP_002124189.1 195978945 6761615 complement(1917767..1918441) 1 NC_011134.1 similar to ref|YP_821152.1| Predicted metal-dependent membrane protease [Streptococcus thermophilus LMD-9]; membrane-bound protease CAAX family 1918441 6761615 Sez_1852 Streptococcus equi subsp. zooepidemicus MGCS10565 membrane-bound protease CAAX family YP_002124189.1 1917767 R 552526 CDS YP_002124190.1 195978946 6761611 complement(1918451..1918903) 1 NC_011134.1 similar to ref|NP_722275.1| hypothetical protein SMU.1976c [Streptococcus mutans UA159]; hypothetical protein 1918903 6761611 Sez_1853 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002124190.1 1918451 R 552526 CDS YP_002124191.1 195978947 6761633 complement(1918905..1919108) 1 NC_011134.1 similar to ref|YP_001451172.1| HTH DNA-binding protein [Streptococcus gordonii str. Challis substr. CH1]; HTH-type transcriptional regulator 1919108 6761633 Sez_1854 Streptococcus equi subsp. zooepidemicus MGCS10565 HTH-type transcriptional regulator YP_002124191.1 1918905 R 552526 CDS YP_002124192.1 195978948 6761603 1919539..1920270 1 NC_011134.1 similar to ref|YP_597530.1| hypothetical protein MGAS9429_Spy1799 [Streptococcus pyogenes MGAS9429]; hypothetical protein 1920270 6761603 Sez_1855 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002124192.1 1919539 D 552526 CDS YP_002124193.1 195978949 6761627 complement(1920254..1920397) 1 NC_011134.1 hypothetical protein 1920397 6761627 Sez_1856 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002124193.1 1920254 R 552526 CDS YP_002124194.1 195978950 6761624 complement(1920731..1921345) 1 NC_011134.1 similar to ref|YP_061106.1| Anaerobic ribonucleoside-triphosphate reductase activating protein [Streptococcus pyogenes MGAS10394]; Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.; anaerobic ribonucleoside-triphosphate reductase-activating protein NrdG 1921345 nrdG 6761624 nrdG Streptococcus equi subsp. zooepidemicus MGCS10565 anaerobic ribonucleoside-triphosphate reductase-activating protein NrdG YP_002124194.1 1920731 R 552526 CDS YP_002124195.1 195978951 6761594 complement(1921355..1921849) 1 NC_011134.1 similar to ref|YP_815708.1| acetyltransferase, GNAT family protein [Streptococcus pneumoniae D39]; acetyltransferase GNAT Family 1921849 6761594 Sez_1858 Streptococcus equi subsp. zooepidemicus MGCS10565 acetyltransferase GNAT Family YP_002124195.1 1921355 R 552526 CDS YP_002124196.1 195978952 6762283 complement(1921862..1922797) 1 NC_011134.1 similar to ref|YP_281240.1| oxidoreductase [Streptococcus pyogenes MGAS6180]; oxidoreductase Mvi-like 1922797 6762283 Sez_1859 Streptococcus equi subsp. zooepidemicus MGCS10565 oxidoreductase Mvi-like YP_002124196.1 1921862 R 552526 CDS YP_002124197.1 195978953 6761283 complement(1922825..1922971) 1 NC_011134.1 similar to ref|NP_608112.1| hypothetical protein spyM18_2167 [Streptococcus pyogenes MGAS8232]; hypothetical protein 1922971 6761283 Sez_1860 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002124197.1 1922825 R 552526 CDS YP_002124198.1 195978954 6761268 complement(1923077..1925275) 1 NC_011134.1 Catalyzes the reduction of nucleoside 5'-triphosphates to 2'-deoxynucleoside 5'-triphosphates; anaerobic ribonucleoside triphosphate reductase 1925275 nrdD 6761268 nrdD Streptococcus equi subsp. zooepidemicus MGCS10565 anaerobic ribonucleoside triphosphate reductase YP_002124198.1 1923077 R 552526 CDS YP_002124199.1 195978955 6761346 complement(1925371..1926906) 1 NC_011134.1 similar to ref|NP_665599.1| hypothetical protein SpyM3_1795 [Streptococcus pyogenes MGAS315]; hypothetical protein 1926906 6761346 Sez_1862 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002124199.1 1925371 R 552526 CDS YP_002124200.1 195978956 6761344 1927075..1927200 1 NC_011134.1 hypothetical protein 1927200 6761344 Sez_1863 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002124200.1 1927075 D 552526 CDS YP_002124201.1 195978957 6761298 complement(1927482..1927781) 1 NC_011134.1 similar to ref|NP_270036.1| hypothetical protein SPy_2112 [Streptococcus pyogenes M1 GAS]; hypothetical protein 1927781 6761298 Sez_1864 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002124201.1 1927482 R 552526 CDS YP_002124202.1 195978958 6761342 complement(1927791..1928201) 1 NC_011134.1 similar to ref|YP_140369.1| Holliday junction resolvase-like protein [Streptococcus thermophilus LMG 18311]; Could be a nuclease that resolves Holliday junction intermediates in genetic recombination.; Holliday junction resolvase RvuC-like 1928201 6761342 Sez_1865 Streptococcus equi subsp. zooepidemicus MGCS10565 Holliday junction resolvase RvuC-like YP_002124202.1 1927791 R 552526 CDS YP_002124203.1 195978959 6761343 complement(1928207..1928476) 1 NC_011134.1 similar to ref|ZP_00365335.1| COG4472: Uncharacterized protein conserved in bacteria [Streptococcus pyogenes M49 591]; hypothetical protein 1928476 6761343 Sez_1866 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002124203.1 1928207 R 552526 CDS YP_002124204.1 195978960 6761341 complement(1928589..1928987) 1 NC_011134.1 the anti-alpha factor Spx interacts with RNA polymerase alpha subunit C-terminal domain in a region that interacts with the sigma 70 subunit and may interfere with activation of promoters; in Bacillus subtilis this protein is a substrate for ClpXP protease; blocks transcription of the competence regulatory gene encoded by the srf operon; regulates a number of genes involved in thiol homeostasis including trxA and trxB; monomeric member of ArsC family of proteins; does not bind DNA; contains a disulfide bond between C10 and C13 which may sense disulfide stress; transcriptional regulator Spx 1928987 spxA 6761341 spxA Streptococcus equi subsp. zooepidemicus MGCS10565 transcriptional regulator Spx YP_002124204.1 1928589 R 552526 CDS YP_002124205.1 195978961 6761317 complement(1929355..1929798) 1 NC_011134.1 similar to ref|YP_140248.1| ISSth1, transposase (orf2), IS3 family [Streptococcus thermophilus LMG 18311]; ISSth1 transposase orfC 1929798 6761317 Sez_1868 Streptococcus equi subsp. zooepidemicus MGCS10565 ISSth1 transposase orfC YP_002124205.1 1929355 R 552526 CDS YP_002124206.1 195978962 6761316 complement(1929782..1930153) 1 NC_011134.1 similar to ref|YP_139290.1| ISSth1, transposase (orf2), IS3 family [Streptococcus thermophilus LMG 18311]; ISSth1 transposase orfB 1930153 6761316 Sez_1869 Streptococcus equi subsp. zooepidemicus MGCS10565 ISSth1 transposase orfB YP_002124206.1 1929782 R 552526 CDS YP_002124207.1 195978963 6761315 complement(1930240..1930926) 1 NC_011134.1 similar to ref|YP_139291.1| ISSth1, transposase (orf1), IS3 family [Streptococcus thermophilus LMG 18311]; ISSth1 transposase orfA 1930926 6761315 Sez_1870 Streptococcus equi subsp. zooepidemicus MGCS10565 ISSth1 transposase orfA YP_002124207.1 1930240 R 552526 CDS YP_002124208.1 195978964 6761337 1931001..1931516 1 NC_011134.1 similar to ref|YP_602677.1| Transposase [Streptococcus pyogenes MGAS10750]; transposase IS861 orfA 1931516 6761337 Sez_1871 Streptococcus equi subsp. zooepidemicus MGCS10565 transposase IS861 orfA YP_002124208.1 1931001 D 552526 CDS YP_002124209.1 195978965 6761336 1931540..1932343 1 NC_011134.1 similar to ref|YP_596865.1| transposase [Streptococcus pyogenes MGAS9429]; transposase IS861 orfB 1932343 6761336 Sez_1872 Streptococcus equi subsp. zooepidemicus MGCS10565 transposase IS861 orfB YP_002124209.1 1931540 D 552526 CDS YP_002124210.1 195978966 6761278 complement(1932481..1933617) 1 NC_011134.1 catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs; recombinase A 1933617 recA 6761278 recA Streptococcus equi subsp. zooepidemicus MGCS10565 recombinase A YP_002124210.1 1932481 R 552526 CDS YP_002124211.1 195978967 6761206 complement(1933711..1934982) 1 NC_011134.1 similar to ref|YP_281249.1| competence damage-inducible protein A [Streptococcus pyogenes MGAS6180]; competence damage-inducible protein A 1934982 cinA 6761206 cinA Streptococcus equi subsp. zooepidemicus MGCS10565 competence damage-inducible protein A YP_002124211.1 1933711 R 552526 CDS YP_002124212.1 195978968 6761237 complement(1935668..1935958) 1 NC_011134.1 similar to ref|YP_280686.1| hypothetical protein M28_Spy1221 [Streptococcus pyogenes MGAS6180]; hypothetical protein 1935958 6761237 Sez_1875 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002124212.1 1935668 R 552526 CDS YP_002124213.1 195978969 6761251 complement(1935952..1936524) 1 NC_011134.1 similar to ref|NP_665008.1| streptococcal phospholipase A2 - phage associated [Streptococcus pyogenes MGAS315]; Cleaves phospholipids at SN2 position.; phosphlipase A2 SlaA 1936524 slaA 6761251 slaA Streptococcus equi subsp. zooepidemicus MGCS10565 phosphlipase A2 SlaA YP_002124213.1 1935952 R 552526 CDS YP_002124214.1 195978970 6761231 1936810..1937763 1 NC_011134.1 similar to ref|YP_138591.1| IS1239 transposase [Streptococcus thermophilus LMG 18311]; transposase IS1239 1937763 6761231 Sez_1877 Streptococcus equi subsp. zooepidemicus MGCS10565 transposase IS1239 YP_002124214.1 1936810 D 552526 CDS YP_002124215.1 195978971 6761254 1937907..1938752 1 NC_011134.1 similar to ref|YP_001036163.1| hypothetical protein SSA_2251 [Streptococcus sanguinis SK36]; hypothetical protein 1938752 6761254 Sez_1878 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002124215.1 1937907 D 552526 CDS YP_002124216.1 195978972 6761219 complement(1939197..1939748) 1 NC_011134.1 similar to ref|YP_281250.1| DNA-3-methyladenine glycosylase [Streptococcus pyogenes MGAS6180]; Catalyzes the synthesis of GMP from XMP.; GMP synthase 1939748 guaA 6761219 guaA Streptococcus equi subsp. zooepidemicus MGCS10565 GMP synthase YP_002124216.1 1939197 R 552526 CDS YP_002124217.1 195978973 6761240 complement(1939758..1940354) 1 NC_011134.1 plays an essential role in ATP-dependent branch migration of the Holliday junction; Holliday junction DNA helicase RuvA 1940354 ruvA 6761240 ruvA Streptococcus equi subsp. zooepidemicus MGCS10565 Holliday junction DNA helicase RuvA YP_002124217.1 1939758 R 552526 CDS YP_002124218.1 195978974 6761217 complement(1940356..1941531) 1 NC_011134.1 similar to ref|YP_597545.1| multidrug resistance protein [Streptococcus pyogenes MGAS9429]; major facilitator family transporter 1941531 6761217 Sez_1881 Streptococcus equi subsp. zooepidemicus MGCS10565 major facilitator family transporter YP_002124218.1 1940356 R 552526 CDS YP_002124219.1 195978975 6761235 complement(1941590..1943572) 1 NC_011134.1 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. Promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex; DNA mismatch repair protein 1943572 mutL 6761235 mutL Streptococcus equi subsp. zooepidemicus MGCS10565 DNA mismatch repair protein YP_002124219.1 1941590 R 552526 CDS YP_002124220.1 195978976 6761234 complement(1943719..1946232) 1 NC_011134.1 This protein performs the mismatch recognition step during the DNA repair process; DNA mismatch repair protein MutS 1946232 mutS 6761234 mutS Streptococcus equi subsp. zooepidemicus MGCS10565 DNA mismatch repair protein MutS YP_002124220.1 1943719 R 552526 CDS YP_002124221.1 195978977 6761213 complement(1946246..1946596) 1 NC_011134.1 similar to ref|NP_722381.1| hypothetical protein SMU.2092c [Streptococcus mutans UA159]; hypothetical protein 1946596 6761213 Sez_1884 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002124221.1 1946246 R 552526 CDS YP_002124222.1 195978978 6761233 complement(1946598..1947035) 1 NC_011134.1 similar to ref|YP_599508.1| Arginine repressor, argR [Streptococcus pyogenes MGAS10270]; Regulates arginine biosynthesis genes; arginine repressor ArgR 1947035 argR 6761233 argR Streptococcus equi subsp. zooepidemicus MGCS10565 arginine repressor ArgR YP_002124222.1 1946598 R 552526 CDS YP_002124223.1 195978979 6761247 complement(1949058..1950452) 1 NC_011134.1 similar to ref|YP_001488305.1| ABC superfamily ATP binding cassette transporter, ABC protein [Bacillus pumilus SAFR-032]; Possibly confers resistance to 14-membered ring macrolides (like erythromycin) and to B streptogramins, by acting as an ATP-dependent efflux pump.; ABC transporter ATP-binding protein 1950452 msrA 6761247 msrA Streptococcus equi subsp. zooepidemicus MGCS10565 ABC transporter ATP-binding protein YP_002124223.1 1949058 R 552526 CDS YP_002124224.1 195978980 6761223 complement(1950624..1951538) 1 NC_011134.1 similar to ref|YP_281284.1| hypothetical membrane spanning protein [Streptococcus pyogenes MGAS6180]; transporter 1951538 6761223 Sez_1889 Streptococcus equi subsp. zooepidemicus MGCS10565 transporter YP_002124224.1 1950624 R 552526 CDS YP_002124225.1 195978981 6761244 complement(1951682..1952563) 1 NC_011134.1 similar to ref|YP_597553.1| hypothetical membrane spanning protein [Streptococcus pyogenes MGAS9429]; hypothetical protein 1952563 6761244 Sez_1890 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002124225.1 1951682 R 552526 CDS YP_002124226.1 195978982 6761243 complement(1952579..1953526) 1 NC_011134.1 similar to ref|ZP_00366175.1| COG1284: Uncharacterized conserved protein [Streptococcus pyogenes M49 591]; hypothetical protein 1953526 6761243 Sez_1891 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002124226.1 1952579 R 552526 CDS YP_002124227.1 195978983 6761211 complement(1953519..1955267) 1 NC_011134.1 catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes; aspartyl-tRNA synthetase 1955267 aspS 6761211 aspS Streptococcus equi subsp. zooepidemicus MGCS10565 aspartyl-tRNA synthetase YP_002124227.1 1953519 R 552526 CDS YP_002124228.1 195978984 6761230 complement(1955495..1956775) 1 NC_011134.1 catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG; histidyl-tRNA synthetase 1956775 hisS 6761230 hisS Streptococcus equi subsp. zooepidemicus MGCS10565 histidyl-tRNA synthetase YP_002124228.1 1955495 R 552526 CDS YP_002124229.1 195978985 6761226 1957184..1957366 1 NC_011134.1 some L32 proteins have zinc finger motifs consisting of CXXC while others do not; 50S ribosomal protein L32 1957366 rpmF 6761226 rpmF Streptococcus equi subsp. zooepidemicus MGCS10565 50S ribosomal protein L32 YP_002124229.1 1957184 D 552526 CDS YP_002124230.1 195978986 6761225 1957382..1957531 1 NC_011134.1 in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif; 50S ribosomal protein L33 1957531 rpmG 6761225 rpmG Streptococcus equi subsp. zooepidemicus MGCS10565 50S ribosomal protein L33 YP_002124230.1 1957382 D 552526 CDS YP_002124231.1 195978987 6761208 complement(1957699..1958991) 1 NC_011134.1 similar to ref|YP_139512.1| IS1193 transposase [Streptococcus thermophilus LMG 18311]; transposase IS1193D 1958991 6761208 Sez_1896 Streptococcus equi subsp. zooepidemicus MGCS10565 transposase IS1193D YP_002124231.1 1957699 R 552526 CDS YP_002124232.1 195978988 6761222 complement(1959248..1960105) 1 NC_011134.1 similar to ref|NP_345531.1| transcriptional regulator PlcR, [Streptococcus pneumoniae TIGR4]; transcriptional regulator PlcR-like 1960105 plcR 6761222 plcR Streptococcus equi subsp. zooepidemicus MGCS10565 transcriptional regulator PlcR-like YP_002124232.1 1959248 R 552526 CDS YP_002124233.1 195978989 6761218 complement(1960147..1961259) 1 NC_011134.1 similar to ref|YP_078429.1| Major facilitator superfamily [Bacillus licheniformis ATCC 14580]; major facilitator family protein 1961259 6761218 Sez_1898 Streptococcus equi subsp. zooepidemicus MGCS10565 major facilitator family protein YP_002124233.1 1960147 R 552526 CDS YP_002124234.1 195978990 6761357 complement(1961324..1962334) 1 NC_011134.1 transporter 1962334 6761357 Sez_1899 Streptococcus equi subsp. zooepidemicus MGCS10565 transporter YP_002124234.1 1961324 R 552526 CDS YP_002124235.1 195978991 6761215 complement(1962324..1963388) 1 NC_011134.1 similar to ref|NP_815050.1| HesA/MoeB/ThiF family protein [Enterococcus faecalis V583]; HesA/MoeB/ThiF family protein 1963388 6761215 Sez_1900 Streptococcus equi subsp. zooepidemicus MGCS10565 HesA/MoeB/ThiF family protein YP_002124235.1 1962324 R 552526 CDS YP_002124236.1 195978992 6761286 1963854..1965734 1 NC_011134.1 similar to gb|AAN18298.1| immunoreactive protein Se68.9 [Streptococcus equi]; Emm-like cell surface protein CspZ.2 1965734 cspZ.2 6761286 cspZ.2 Streptococcus equi subsp. zooepidemicus MGCS10565 Emm-like cell surface protein CspZ.2 YP_002124236.1 1963854 D 552526 CDS YP_002124237.1 195978993 6761356 1965964..1967766 1 NC_011134.1 similar to ref|NP_830667.1| Sensor protein comP [Bacillus cereus ATCC 14579]; TCS sensor kinase 1967766 6761356 Sez_1902 Streptococcus equi subsp. zooepidemicus MGCS10565 TCS sensor kinase YP_002124237.1 1965964 D 552526 CDS YP_002124238.1 195978994 6760357 1967744..1968343 1 NC_011134.1 similar to ref|YP_001196982.1| two component transcriptional regulator, LuxR family [Flavobacterium johnsoniae UW101]; TCS response regulator 1968343 6760357 Sez_1903 Streptococcus equi subsp. zooepidemicus MGCS10565 TCS response regulator YP_002124238.1 1967744 D 552526 CDS YP_002124239.1 195978995 6760523 1968451..1969377 1 NC_011134.1 similar to gb|AAC33119.1| avirulence D protein [Pseudomonas syringae pv. cilantro]; avirulence AvrD-like protein 1969377 6760523 Sez_1904 Streptococcus equi subsp. zooepidemicus MGCS10565 avirulence AvrD-like protein YP_002124239.1 1968451 D 552526 CDS YP_002124240.1 195978996 6760546 1969370..1970146 1 NC_011134.1 similar to ref|YP_873838.1| hypothetical protein Acel_2080 [Acidothermus cellulolyticus 11B]; hypothetical protein 1970146 6760546 Sez_1905 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002124240.1 1969370 D 552526 CDS YP_002124241.1 195978997 6760538 1970155..1970826 1 NC_011134.1 similar to ref|ZP_01940408.1| ABC transporter, ATP-binding protein [Listeria monocytogenes 10403S]; ABC transporter ATP-binding protein 1970826 6760538 Sez_1906 Streptococcus equi subsp. zooepidemicus MGCS10565 ABC transporter ATP-binding protein YP_002124241.1 1970155 D 552526 CDS YP_002124242.1 195978998 6760723 1970831..1973116 1 NC_011134.1 similar to gb|AAN18297.1| ABC transporter permease [Streptococcus equi]; ABC transporter permease 1973116 6760723 Sez_1907 Streptococcus equi subsp. zooepidemicus MGCS10565 ABC transporter permease YP_002124242.1 1970831 D 552526 CDS YP_002124243.1 195978999 6760533 1973586..1974401 1 NC_011134.1 hypothetical protein 1974401 6760533 Sez_1908 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002124243.1 1973586 D 552526 CDS YP_002124244.1 195979000 6760413 1974173..1974811 1 NC_011134.1 similar to ref|XP_312188.4| AGAP002737-PA [Anopheles gambiae str. PEST]; hypothetical protein 1974811 6760413 Sez_1909 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002124244.1 1974173 D 552526 CDS YP_002124245.1 195979001 6760860 1975927..1976769 1 NC_011134.1 similar to ref|YP_599528.1| Integral membrane protein [Streptococcus pyogenes MGAS10270]; hypothetical protein 1976769 6760860 Sez_1911 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002124245.1 1975927 D 552526 CDS YP_002124246.1 195979002 6760807 complement(1976856..1977482) 1 NC_011134.1 similar to ref|YP_599529.1| Phosphohydrolase [Streptococcus pyogenes MGAS10270]; Probably mediates the hydrolysis of some nucleoside diphosphate derivatives.; phosphohydrolase MutT/nudix family protein 1977482 6760807 Sez_1912 Streptococcus equi subsp. zooepidemicus MGCS10565 phosphohydrolase MutT/nudix family protein YP_002124246.1 1976856 R 552526 CDS YP_002124247.1 195979003 6761354 1977684..1978010 1 NC_011134.1 similar to ref|YP_061164.1| Transcriptional regulator, PadR family [Streptococcus pyogenes MGAS10394]; transcriptional regulator PadR family 1978010 6761354 Sez_1913 Streptococcus equi subsp. zooepidemicus MGCS10565 transcriptional regulator PadR family YP_002124247.1 1977684 D 552526 CDS YP_002124248.1 195979004 6761347 1977997..1978356 1 NC_011134.1 hypothetical protein 1978356 6761347 Sez_1914 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002124248.1 1977997 D 552526 CDS YP_002124249.1 195979005 6761335 1978375..1979430 1 NC_011134.1 similar to ref|YP_001449372.1| hypothetical protein SGO_0050 [Streptococcus gordonii str. Challis substr. CH1]; hypothetical protein 1979430 6761335 Sez_1915 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002124249.1 1978375 D 552526 CDS YP_002124250.1 195979006 6761310 complement(1979533..1981812) 1 NC_011134.1 similar to ref|NP_608148.1| hypothetical protein spyM18_2213 [Streptococcus pyogenes MGAS8232]; hypothetical protein 1981812 6761310 Sez_1916 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002124250.1 1979533 R 552526 CDS YP_002124251.1 195979007 6761332 1981875..1982477 1 NC_011134.1 similar to ref|NP_270087.1| transcriptional regulator (TetR/AcrR family) [Streptococcus pyogenes M1 GAS]; TetR family transcriptional regulator 1982477 6761332 Sez_1917 Streptococcus equi subsp. zooepidemicus MGCS10565 TetR family transcriptional regulator YP_002124251.1 1981875 D 552526 CDS YP_002124252.1 195979008 6761331 complement(1982916..1983263) 1 NC_011134.1 similar to ref|ZP_00787238.1| conserved hypothetical protein [Streptococcus agalactiae CJB111]; hypothetical protein 1983263 6761331 Sez_1918 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002124252.1 1982916 R 552526 CDS YP_002124253.1 195979009 6761305 complement(1983253..1983540) 1 NC_011134.1 similar to ref|ZP_00787181.1| Unknown, [Streptococcus agalactiae CJB111]; hypothetical protein 1983540 6761305 Sez_1919 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002124253.1 1983253 R 552526 CDS YP_002124254.1 195979010 6761325 complement(1983645..1983776) 1 NC_011134.1 similar to ref|YP_330669.1| prophage Sa05, transcriptional regulator, ArpU family [Streptococcus agalactiae A909]; transcriptional regulator phage associated ArpU family 1983776 6761325 Sez_1920 Streptococcus equi subsp. zooepidemicus MGCS10565 transcriptional regulator phage associated ArpU family YP_002124254.1 1983645 R 552526 CDS YP_002124255.1 195979011 6761323 complement(1984032..1984343) 1 NC_011134.1 similar to ref|YP_001129292.1| DNA-binding phage protein [Streptococcus pyogenes str. Manfredo]; phage associated protein 1984343 6761323 Sez_1921 Streptococcus equi subsp. zooepidemicus MGCS10565 phage associated protein YP_002124255.1 1984032 R 552526 CDS YP_002124256.1 195979012 6761318 complement(1984693..1985304) 1 NC_011134.1 primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination; 30S ribosomal protein S4 1985304 rpsD 6761318 rpsD Streptococcus equi subsp. zooepidemicus MGCS10565 30S ribosomal protein S4 YP_002124256.1 1984693 R 552526 CDS YP_002124257.1 195979013 6761292 1985828..1987120 1 NC_011134.1 similar to ref|ZP_00875692.1| Transposase, IS204/IS1001/IS1096/IS1165 [Streptococcus suis 89/1591]; transposase IS1193D 1987120 6761292 Sez_1923 Streptococcus equi subsp. zooepidemicus MGCS10565 transposase IS1193D YP_002124257.1 1985828 D 552526 CDS YP_002124258.1 195979014 6761302 complement(1987162..1987434) 1 NC_011134.1 similar to ref|YP_061170.1| hypothetical protein M6_Spy1852 [Streptococcus pyogenes MGAS10394]; hypothetical protein 1987434 6761302 Sez_1924 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002124258.1 1987162 R 552526 CDS YP_002124259.1 195979015 6761284 complement(1987451..1988827) 1 NC_011134.1 unwinds double stranded DNA; replicative DNA helicase 1988827 6761284 Sez_1925 Streptococcus equi subsp. zooepidemicus MGCS10565 replicative DNA helicase YP_002124259.1 1987451 R 552526 CDS YP_002124260.1 195979016 6761328 complement(1988848..1989300) 1 NC_011134.1 in Escherichia coli this protein is wrapped around the base of the L1 stalk; 50S ribosomal protein L9 1989300 rplI 6761328 rplI Streptococcus equi subsp. zooepidemicus MGCS10565 50S ribosomal protein L9 YP_002124260.1 1988848 R 552526 CDS YP_002124261.1 195979017 6761282 complement(1989297..1991273) 1 NC_011134.1 similar to ref|YP_599565.1| Phosphoesterase, DHH family protein [Streptococcus pyogenes MGAS10270]; phosphoesterase DHH family protein 1991273 6761282 Sez_1927 Streptococcus equi subsp. zooepidemicus MGCS10565 phosphoesterase DHH family protein YP_002124261.1 1989297 R 552526 CDS YP_002124262.1 195979018 6761350 complement(1993263..1993727) 1 NC_011134.1 similar to ref|YP_815645.1| MutT/nudix family protein [Streptococcus pneumoniae D39]; MutT/nudix family protein 1993727 6761350 Sez_1930 Streptococcus equi subsp. zooepidemicus MGCS10565 MutT/nudix family protein YP_002124262.1 1993263 R 552526 CDS YP_002124263.1 195979019 6761258 complement(1993932..1995056) 1 NC_011134.1 catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs; tRNA-specific 2-thiouridylase MnmA 1995056 mnmA 6761258 mnmA Streptococcus equi subsp. zooepidemicus MGCS10565 tRNA-specific 2-thiouridylase MnmA YP_002124263.1 1993932 R 552526 CDS YP_002124264.1 195979020 6761274 complement(1995150..1995275) 1 NC_011134.1 hypothetical protein 1995275 6761274 Sez_1932 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002124264.1 1995150 R 552526 CDS YP_002124265.1 195979021 6761273 1995339..1996010 1 NC_011134.1 similar to ref|YP_061176.1| L-serine dehydratase beta subunit [Streptococcus pyogenes MGAS10394]; Catalysis of the reaction: L-serine = pyruvate + NH3.; L-serine dehydratase subunit beta SdaAB 1996010 sdaAB 6761273 sdaAB Streptococcus equi subsp. zooepidemicus MGCS10565 L-serine dehydratase subunit beta SdaAB YP_002124265.1 1995339 D 552526 CDS YP_002124266.1 195979022 6761202 1996022..1996894 1 NC_011134.1 similar to ref|YP_599570.1| L-serinedehydratase alpha subunit [Streptococcus pyogenes MGAS10270]; Catalysis of the reaction: L-serine = pyruvate + NH3.; L-serine dehydratase subunit alpha SdaAA 1996894 sdaAA 6761202 sdaAA Streptococcus equi subsp. zooepidemicus MGCS10565 L-serine dehydratase subunit alpha SdaAA YP_002124266.1 1996022 D 552526 CDS YP_002124267.1 195979023 6761270 1996928..1997563 1 NC_011134.1 similar to ref|YP_001036270.1| Phosphoglycolate phosphatase, [Streptococcus sanguinis SK36]; Catalysis of the reaction: 2-phosphoglycolate + H2O = glycolate + phosphate.; phosphoglycolate phosphatase 1997563 6761270 Sez_1935 Streptococcus equi subsp. zooepidemicus MGCS10565 phosphoglycolate phosphatase YP_002124267.1 1996928 D 552526 CDS YP_002124268.1 195979024 6761269 complement(1997625..1998236) 1 NC_011134.1 similar to ref|YP_597585.1| transglycosylase SLT domain family protein [Streptococcus pyogenes MGAS9429]; hypothetical protein 1998236 6761269 Sez_1936 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002124268.1 1997625 R 552526 CDS YP_002124269.1 195979025 6761265 complement(1998491..1999300) 1 NC_011134.1 similar to ref|ZP_00366389.1| COG0619: ABC-type cobalt transport system, permease component CbiQ and related transporters [Streptococcus pyogenes M49 591]; Part of the ABC transporter complex cbiONQ involved in cobalt import. Transmembrane domains (TMD) form a pore in the membrane and the ATP-binding domain (NBD) is responsible for energy generation.; cobalt import ATP-binding/permease CbiO 1999300 cbiO 6761265 cbiO Streptococcus equi subsp. zooepidemicus MGCS10565 cobalt import ATP-binding/permease CbiO YP_002124269.1 1998491 R 552526 CDS YP_002124270.1 195979026 6761264 complement(1999293..2000135) 1 NC_011134.1 with CbiNQ forms the ABC transporter for cobalt import; Streptococcus has two adjacent copies of this gene; cobalt transporter ATP-binding subunit 2000135 cbiO 6761264 cbiO Streptococcus equi subsp. zooepidemicus MGCS10565 cobalt transporter ATP-binding subunit YP_002124270.1 1999293 R 552526 CDS YP_002124271.1 195979027 6761242 complement(2000111..2000950) 1 NC_011134.1 with CbiNQ forms the ABC transporter for cobalt import; Streptococcus has two adjacent copies of this gene; cobalt transporter ATP-binding subunit 2000950 cbiO 6761242 cbiO Streptococcus equi subsp. zooepidemicus MGCS10565 cobalt transporter ATP-binding subunit YP_002124271.1 2000111 R 552526 CDS YP_002124272.1 195979028 6761259 complement(2000953..2001495) 1 NC_011134.1 similar to gb|ABW75773.1| CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase [Streptococcus equi subsp. zooepidemicus]; Catalysis of the reaction: CDP-diacylglycerol + glycerol 3-phosphate = CMP + 3-(3-phosphatidyl)-glycerol 1-phosphate.; CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase 2001495 pgsA 6761259 pgsA Streptococcus equi subsp. zooepidemicus MGCS10565 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase YP_002124272.1 2000953 R 552526 CDS YP_002124273.1 195979029 6761238 complement(2001508..2001966) 1 NC_011134.1 similar to ref|ZP_00366385.1| COG1426: Uncharacterized protein conserved in bacteria [Streptococcus pyogenes M49 591]; hypothetical protein 2001966 6761238 Sez_1941 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002124273.1 2001508 R 552526 CDS YP_002124274.1 195979030 6761334 complement(2001920..2002513) 1 NC_011134.1 similar to ref|YP_281345.1| hypothetical membrane associated protein [Streptococcus pyogenes MGAS6180]; hypothetical protein 2002513 6761334 Sez_1942 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002124274.1 2001920 R 552526 CDS YP_002124275.1 195979031 6761333 complement(2002563..2003846) 1 NC_011134.1 similar to ref|YP_603459.1| Zinc protease [Streptococcus pyogenes MGAS10750]; zinc protease 2003846 6761333 Sez_1943 Streptococcus equi subsp. zooepidemicus MGCS10565 zinc protease YP_002124275.1 2002563 R 552526 CDS YP_002124276.1 195979032 6761329 complement(2003848..2005092) 1 NC_011134.1 similar to ref|YP_061185.1| Zinc protease [Streptococcus pyogenes MGAS10394]; zinc protease 2005092 6761329 Sez_1944 Streptococcus equi subsp. zooepidemicus MGCS10565 zinc protease YP_002124276.1 2003848 R 552526 CDS YP_002124277.1 195979033 6761330 2005301..2005720 1 NC_011134.1 similar to ref|YP_597596.1| hypothetical cytosolic protein [Streptococcus pyogenes MGAS9429]; hypothetical protein 2005720 6761330 Sez_1945 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002124277.1 2005301 D 552526 CDS YP_002124278.1 195979034 6761303 2005722..2006831 1 NC_011134.1 Required for DNA replication; binds preferentially to single-stranded, linear DNA; recombination protein F 2006831 recF 6761303 recF Streptococcus equi subsp. zooepidemicus MGCS10565 recombination protein F YP_002124278.1 2005722 D 552526 CDS YP_002124279.1 195979035 6761324 complement(2006895..2007728) 1 NC_011134.1 similar to ref|YP_283219.1| glucose uptake protein homolog [Streptococcus pyogenes MGAS5005]; sugar uptake protein 2007728 6761324 Sez_1947 Streptococcus equi subsp. zooepidemicus MGCS10565 sugar uptake protein YP_002124279.1 2006895 R 552526 CDS YP_002124280.1 195979036 6761321 complement(2007929..2010358) 1 NC_011134.1 similar to ref|NP_466326.1| hypothetical protein lmo2804 [Listeria monocytogenes EGD-e]; hypothetical protein 2010358 6761321 Sez_1948 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002124280.1 2007929 R 552526 CDS YP_002124281.1 195979037 6761293 complement(2010361..2010756) 1 NC_011134.1 similar to ref|YP_001034253.1| hypothetical protein SSA_0244 [Streptococcus sanguinis SK36]; hypothetical protein 2010756 6761293 Sez_1949 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002124281.1 2010361 R 552526 CDS YP_002124282.1 195979038 6761288 complement(2010753..2011154) 1 NC_011134.1 similar to ref|YP_001034253.1| hypothetical protein SSA_0244 [Streptococcus sanguinis SK36]; hypothetical protein 2011154 6761288 Sez_1950 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002124282.1 2010753 R 552526 CDS YP_002124283.1 195979039 6761285 complement(2011151..2011552) 1 NC_011134.1 similar to ref|ZP_01928725.1| hypothetical protein LMHG_00511 [Listeria monocytogenes FSL N1-017]; hypothetical protein 2011552 6761285 Sez_1951 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002124283.1 2011151 R 552526 CDS YP_002124284.1 195979040 6762348 2011718..2011849 1 NC_011134.1 hypothetical protein 2011849 6762348 Sez_1952 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002124284.1 2011718 D 552526 CDS YP_002124285.1 195979041 6761125 complement(2011933..2013414) 1 NC_011134.1 catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate; inosine 5'-monophosphate dehydrogenase 2013414 guaB 6761125 guaB Streptococcus equi subsp. zooepidemicus MGCS10565 inosine 5'-monophosphate dehydrogenase YP_002124285.1 2011933 R 552526 CDS YP_002124286.1 195979042 6761109 complement(2013615..2014637) 1 NC_011134.1 catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; tryptophanyl-tRNA synthetase 2014637 trpS 6761109 trpS Streptococcus equi subsp. zooepidemicus MGCS10565 tryptophanyl-tRNA synthetase YP_002124286.1 2013615 R 552526 CDS YP_002124287.1 195979043 6761160 2015054..2015644 1 NC_011134.1 similar to ref|NP_270115.1| hypothetical protein SPy_2209 [Streptococcus pyogenes M1 GAS]; hypothetical protein 2015644 6761160 Sez_1955 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002124287.1 2015054 D 552526 CDS YP_002124288.1 195979044 6761161 2015641..2015925 1 NC_011134.1 similar to ref|YP_001129344.1| hypothetical protein SpyM51832 [Streptococcus pyogenes str. Manfredo]; hypothetical protein 2015925 6761161 Sez_1956 Streptococcus equi subsp. zooepidemicus MGCS10565 hypothetical protein YP_002124288.1 2015641 D 552526 CDS YP_002124289.1 195979045 6761177 2016005..2017624 1 NC_011134.1 similar to ref|NP_270116.1| ABC transporter, ATP-binding protein [Streptococcus pyogenes M1 GAS]; ABC transporter ATP-binding protein 2017624 6761177 Sez_1957 Streptococcus equi subsp. zooepidemicus MGCS10565 ABC transporter ATP-binding protein YP_002124289.1 2016005 D 552526 CDS YP_002124290.1 195979046 6761184 2017748..2020333 1 NC_011134.1 similar to ref|NP_665665.1| ABC transporter, permease [Streptococcus pyogenes MGAS315]; ABC transporter permease 2020333 6761184 Sez_1958 Streptococcus equi subsp. zooepidemicus MGCS10565 ABC transporter permease YP_002124290.1 2017748 D 552526 CDS YP_002124291.1 195979047 6761148 complement(2021365..2021844) 1 NC_011134.1 SPOUT methyltransferase family protein; crystal structure shows homodimer; in Escherichia coli this protein methylates pseudouridine at position 1915 of the 23S ribosomal RNA; rRNA large subunit methyltransferase 2021844 6761148 Sez_1959 Streptococcus equi subsp. zooepidemicus MGCS10565 rRNA large subunit methyltransferase YP_002124291.1 2021365 R 552526 CDS YP_002124292.1 195979048 6761178 2022054..2023277 1 NC_011134.1 similar to ref|NP_270119.1| serine protease [Streptococcus pyogenes M1 GAS]; Degrades abnormal exported proteins. Needed for the propeptide processing of a natural pro-protein and for the maturation of a native protein. Responsible for the housekeeping of exported proteins.; serine protease do-like HtrA 2023277 6761178 Sez_1960 Streptococcus equi subsp. zooepidemicus MGCS10565 serine protease do-like HtrA YP_002124292.1 2022054 D 552526 CDS YP_002124293.1 195979049 6761175 2023397..2024170 1 NC_011134.1 similar to ref|YP_061204.1| Chromosome partitioning protein [Streptococcus pyogenes MGAS10394]; Required for the initiation of sporulation and for normal chromosome segregation. Antagonizes sporulation inhibition of soj. It probably interacts with a specific DNA site and other proteins involved in partitioning and cell division, and antagonizes soj in response to cell cycle events related to chromosome partitioning.; chromosome partitioning ATPase 2024170 parB 6761175 parB Streptococcus equi subsp. zooepidemicus MGCS10565 chromosome partitioning ATPase YP_002124293.1 2023397 D 552526 CDS