-- dump date 20140620_081935 -- class Genbank::Feature -- table feature -- table main -- field 1 id -- field 2 type -- field 3 name -- field 4 contig -- field 5 start_pos -- field 6 end_pos -- field 7 strand -- field 8 description -- field 9 chrom_position -- field 10 organism -- field 11 GeneID -- header -- id type name contig start_pos end_pos strand description chrom_position organism GeneID 552526000001 SEQ_END SEQ_END NC_011134.1 2024171 2024171 DR NC_011134.1; contig end 2024171..2024171 Streptococcus equi subsp. zooepidemicus MGCS10565 YP_002122401.1 CDS dnaA NC_011134.1 233 1585 D binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication; can also affect transcription of multiple genes including itself.; chromosome replication initiator DnaA 233..1585 Streptococcus equi subsp. zooepidemicus MGCS10565 6760380 YP_002122402.1 CDS dnaN NC_011134.1 1742 2878 D binds the polymerase to DNA and acts as a sliding clamp; DNA polymerase III subunit beta 1742..2878 Streptococcus equi subsp. zooepidemicus MGCS10565 6760876 YP_002122403.1 CDS Sez_0003 NC_011134.1 2956 3153 D similar to ref|ZP_00784446.1| conserved hypothetical protein [Streptococcus agalactiae COH1]; hypothetical protein 2956..3153 Streptococcus equi subsp. zooepidemicus MGCS10565 6760878 YP_002122404.1 CDS Sez_0004 NC_011134.1 3274 3639 D similar to ref|YP_001199566.1| Predicted transcriptional regulator [Streptococcus suis 98HAH33]; Unknown, COG1396 Predicted transcriptional regulators.; hypothetical protein 3274..3639 Streptococcus equi subsp. zooepidemicus MGCS10565 6760883 YP_002122405.1 CDS Sez_0005 NC_011134.1 3723 4838 D translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1; GTP-dependent nucleic acid-binding protein EngD 3723..4838 Streptococcus equi subsp. zooepidemicus MGCS10565 6761764 YP_002122406.1 CDS pth NC_011134.1 4995 5564 D Enables the recycling of peptidyl-tRNAs produced at termination of translation; peptidyl-tRNA hydrolase 4995..5564 Streptococcus equi subsp. zooepidemicus MGCS10565 6761698 YP_002122407.1 CDS Sez_0007 NC_011134.1 5567 9061 D similar to ref|NP_801268.1| transcription-repair coupling factor [Streptococcus pyogenes SSI-1]; Necessary for strand-specific repair. A lesion in the template strand blocks the RNA polymerase complex (RNAP). The RNAP-DNA-RNA complex is specifically recognized by TRCF which releases RNAP and the truncated transcript; the TCRF may replace RNAP at the lesion site and then recruit the uvrA/B/C repair system.; transcription-repair coupling factor 5567..9061 Streptococcus equi subsp. zooepidemicus MGCS10565 6761703 YP_002122408.1 CDS Sez_0008 NC_011134.1 9030 10541 D similar to ref|NP_814052.1| polysaccharide biosynthesis family protein [Enterococcus faecalis V583]; Unknown, COG2244 Membrane protein involved in the export of O-antigen and teichoic acid.; polysaccharide biosynthesis family protein 9030..10541 Streptococcus equi subsp. zooepidemicus MGCS10565 6760885 YP_002122409.1 CDS Sez_0009 NC_011134.1 10572 10844 D similar to ref|ZP_00780251.1| S4 RNA-binding domain protein [Streptococcus agalactiae 18RS21]; Unknown, COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog).; heat shock protein 15 10572..10844 Streptococcus equi subsp. zooepidemicus MGCS10565 6760884 YP_002122410.1 CDS Sez_0010 NC_011134.1 10855 11202 D similar to ref|YP_599604.1| Cell division protein DIVIC [Streptococcus pyogenes MGAS2096]; cell division protein DivIC 10855..11202 Streptococcus equi subsp. zooepidemicus MGCS10565 6761743 YP_002122411.1 CDS Sez_0011 NC_011134.1 11344 12630 D similar to ref|ZP_00366568.1| COG2367: Beta-lactamase class A [Streptococcus pyogenes M49 591]; beta-lactamase 11344..12630 Streptococcus equi subsp. zooepidemicus MGCS10565 6761733 YP_002122412.1 CDS Sez_0012 NC_011134.1 12627 13910 D similar to ref|YP_059329.1| tRNA(Ile)-lysidine synthetase [Streptococcus pyogenes MGAS10394]; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.; tRNA(Ile)-lysidine synthase 12627..13910 Streptococcus equi subsp. zooepidemicus MGCS10565 6760881 YP_002122413.1 CDS hpt NC_011134.1 13915 14457 D similar to ref|NP_606347.1| hypoxanthine-guanine phosphoribosyltransferase [Streptococcus pyogenes MGAS8232]; This Enzyme Acts Exclusively On Hypoxanthine; It Does Not Act On Guanine (By Similarity).; hypoxanthine-guanine phosphoribosyltransferase Hpt 13915..14457 Streptococcus equi subsp. zooepidemicus MGCS10565 6761742 YP_002122414.1 CDS ftsH NC_011134.1 14533 16452 D similar to ref|YP_279483.1| cell division protein [Streptococcus pyogenes MGAS6180]; Seems to act as an ATP-dependent zinc metallopeptidase.; cell division protein FtsH-like 14533..16452 Streptococcus equi subsp. zooepidemicus MGCS10565 6761729 YP_002122415.1 CDS Sez_0015 NC_011134.1 16542 18005 D similar to ref|YP_059333.1| Amino acid permease [Streptococcus pyogenes MGAS10394]; Involved in the transport of the cationic amino acids (arginine, lysine and ornithine).; cationic amino acid transporter - APC superfamily 16542..18005 Streptococcus equi subsp. zooepidemicus MGCS10565 6760882 YP_002122416.1 CDS mreC NC_011134.1 24838 25701 D similar to ref|NP_346626.1| rod shape-determining protein MreC [Streptococcus pneumoniae TIGR4]; Involved In Formation Of The Rod Shape Of The Cell. May Also Contribute To Regulation Of Formation Of Penicillin-Binding Proteins.; rod shape-determining protein MreC 24838..25701 Streptococcus equi subsp. zooepidemicus MGCS10565 6761046 YP_002122417.1 CDS mreD NC_011134.1 25704 26207 D similar to ref|NP_720504.1| cell shape-determining protein MreD [Streptococcus mutans UA159]; MreD (murein formation D) protein is involved in the rod shape determination in Escherichia coli, and more generally in cell shape determination of bacteria whether or not they are rod-shaped.; cell shape-determining protein MreD 25704..26207 Streptococcus equi subsp. zooepidemicus MGCS10565 6761786 YP_002122418.1 CDS Sez_0018 NC_011134.1 26303 27481 D similar to ref|YP_597626.1| Secreted protein [Streptococcus pyogenes MGAS10270]; pfam05257, CHAP domain. This domain corresponds to an amidase function. Many of these proteins are involved in cell wall metabolism of bacteria. This domain is found at the N-terminus of the bifunctional Escherichia coli GSP synthetase/GSP amidase, where is functions as a glutathionylspermidine amidase.; secreted antigen GbpB/SagA/PcsB, peptidoglycan hydrolase 26303..27481 Streptococcus equi subsp. zooepidemicus MGCS10565 6761695 YP_002122419.1 CDS prs NC_011134.1 27574 28548 D catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP; ribose-phosphate pyrophosphokinase 27574..28548 Streptococcus equi subsp. zooepidemicus MGCS10565 6760874 YP_002122420.1 CDS recO NC_011134.1 28908 29678 D involved in DNA repair and RecFOR pathway recombination; RecFOR proteins displace ssDNA-binding protein and facilitate the production of RecA-coated ssDNA; DNA repair protein RecO 28908..29678 Streptococcus equi subsp. zooepidemicus MGCS10565 6760858 YP_002122421.1 CDS plsX NC_011134.1 29794 30801 D involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsY; glycerol-3-phosphate acyltransferase PlsX 29794..30801 Streptococcus equi subsp. zooepidemicus MGCS10565 6760686 YP_002122422.1 CDS acpP NC_011134.1 30794 31042 D carries the fatty acid chain in fatty acid biosynthesis; acyl carrier protein 30794..31042 Streptococcus equi subsp. zooepidemicus MGCS10565 6760785 YP_002122423.1 CDS purC NC_011134.1 31193 31903 D catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis; SAICAR synthase; phosphoribosylaminoimidazolesuccinocarboxamide synthase 31193..31903 Streptococcus equi subsp. zooepidemicus MGCS10565 6760696 YP_002122424.1 CDS purL NC_011134.1 32082 35822 D similar to ref|YP_819618.1| Phosphoribosylformylglycinamidine (FGAM) synthase [Streptococcus thermophilus LMD-9]; Unknown, proposed to phosphorylate an amide oxygen of the purine nucleotide using ATP, activating the carbon of the resulting iminophosphate for nucleophilic attack.; phosphoribosylformylglycinamidine synthase PurL 32082..35822 Streptococcus equi subsp. zooepidemicus MGCS10565 6760680 YP_002122425.1 CDS purF NC_011134.1 35941 37398 D Catalyzes first step of the de novo purine nucleotide biosynthetic pathway; amidophosphoribosyltransferase 35941..37398 Streptococcus equi subsp. zooepidemicus MGCS10565 6760614 YP_002122426.1 CDS purM NC_011134.1 37455 38477 D catalyzes the formation of 1-(5-phosphoribosyl)-5-aminoimidazole from 2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in purine biosynthesis; phosphoribosylaminoimidazole synthetase 37455..38477 Streptococcus equi subsp. zooepidemicus MGCS10565 6760583 YP_002122427.1 CDS purN NC_011134.1 38474 39031 D glycinamide ribonucleotide transformylase; GAR Tfase; catalyzes the synthesis of 5'-phosphoribosylformylglycinamide from 5'-phosphoribosylglycinamide and 10-formyltetrahydrofolate; PurN requires formyl folate for the reaction unlike PurT which uses formate; phosphoribosylglycinamide formyltransferase 38474..39031 Streptococcus equi subsp. zooepidemicus MGCS10565 6761655 YP_002122428.1 CDS purH NC_011134.1 39223 40725 D involved in de novo purine biosynthesis; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 39223..40725 Streptococcus equi subsp. zooepidemicus MGCS10565 6761679 YP_002122429.1 CDS Sez_0029 NC_011134.1 41103 42257 R similar to ref|YP_281392.1| autolysin [Streptococcus pyogenes MGAS5005]; Unknown, surface antigen; autolysin; choline binding protein.; autolysin complement(41103..42257) Streptococcus equi subsp. zooepidemicus MGCS10565 6761613 YP_002122430.1 CDS purD NC_011134.1 42571 43875 D catalyzes the formation of N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-D-ribosylamine and glycine in purine biosynthesis; phosphoribosylamine--glycine ligase 42571..43875 Streptococcus equi subsp. zooepidemicus MGCS10565 6760875 YP_002122431.1 CDS purE NC_011134.1 44103 44591 D similar to ref|YP_001127629.1| phosphoribosylaminoimidazole carboxylase catalytic subunit [Streptococcus pyogenes str. Manfredo]; This subunit can alone transform AIR to CAIR, but in association with purK, which possesses an ATPase activity, an enzyme complex is produced which is capable of converting AIR to CAIR efficiently under physiological condition.; phosphoribosylaminoimidazole carboxylase catalytic subunit PurE 44103..44591 Streptococcus equi subsp. zooepidemicus MGCS10565 6761674 YP_002122432.1 CDS purK NC_011134.1 44578 45669 D With PurE catalyzes the conversion of aminoimidazole ribonucleotide to carboxyaminoimidazole ribonucleotide in the de novo purine nucleotide biosynthetic pathway; phosphoribosylaminoimidazole carboxylase ATPase subunit 44578..45669 Streptococcus equi subsp. zooepidemicus MGCS10565 6760877 YP_002122433.1 CDS Sez_0033 NC_011134.1 45679 45903 D similar to ref|NP_734515.1| hypothetical protein gbs0045 [Streptococcus agalactiae NEM316]; hypothetical protein 45679..45903 Streptococcus equi subsp. zooepidemicus MGCS10565 6760873 YP_002122434.1 CDS Sez_0036 NC_011134.1 47940 48854 D similar to ref|YP_059401.1| Transcriptional regulator [Streptococcus pyogenes MGAS10394]; transcriptional regulator 47940..48854 Streptococcus equi subsp. zooepidemicus MGCS10565 6761463 YP_002122435.1 CDS ruvB NC_011134.1 49069 50070 D promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration; Holliday junction DNA helicase RuvB 49069..50070 Streptococcus equi subsp. zooepidemicus MGCS10565 6761475 YP_002122436.1 CDS Sez_0038 NC_011134.1 50082 50270 R hypothetical protein complement(50082..50270) Streptococcus equi subsp. zooepidemicus MGCS10565 6760879 YP_002122437.1 CDS acp1 NC_011134.1 50356 50814 D similar to ref|NP_268454.1| protein-tyrosine phosphatase [Streptococcus pyogenes M1 GAS]; Acts on tyrosine phosphorylated proteins, low-MW aryl phosphates and natural and synthetic acyl phosphates. Isoform 3 does not possess phosphatase activity.; phosphotyrosine protein phosphatase 50356..50814 Streptococcus equi subsp. zooepidemicus MGCS10565 6761704 YP_002122438.1 CDS Sez_0040 NC_011134.1 50820 51221 D similar to ref|NP_606371.1| hypothetical protein spyM18_0041 [Streptococcus pyogenes MGAS8232]; Unknown, MORN repeat motif family protein.; hypothetical protein 50820..51221 Streptococcus equi subsp. zooepidemicus MGCS10565 6761751 YP_002122439.1 CDS adh2 NC_011134.1 53419 56061 D similar to ref|YP_281403.1| alcohol dehydrogenase/acetaldehyde dehydrogenase (acetylating) [Streptococcus pyogenes MGAS5005]; This enzyme has two NAD(+)-dependent activities:ADH and ACDH. May be a critical enzyme in the fermentative pathway.; bifunctional acetaldehyde-CoA/alcohol dehydrogenase 53419..56061 Streptococcus equi subsp. zooepidemicus MGCS10565 6761652 YP_002122440.1 CDS Sez_0044 NC_011134.1 56329 56535 D hypothetical protein 56329..56535 Streptococcus equi subsp. zooepidemicus MGCS10565 6761671 YP_002122441.1 CDS adh NC_011134.1 56556 57608 D similar to ref|YP_598559.1| Zn-dependent alcohol dehydrogenase [Streptococcus pyogenes MGAS10270]; Zn-dependent alcohol dehydrogenases and related dehydrogenases 56556..57608 Streptococcus equi subsp. zooepidemicus MGCS10565 6760792 YP_002122442.1 CDS adhA NC_011134.1 57813 58829 D similar to zinc-dependent eukaryotic ADH enzymes and distinct from fermentative ADHs; alcohol dehydrogenase 57813..58829 Streptococcus equi subsp. zooepidemicus MGCS10565 6760880 YP_002122443.1 CDS Sez_0047 NC_011134.1 59549 61141 D similar to ref|YP_001034708.1| ABC-type multidrug/protein/lipid transport system (pediocin PA-1 exporter), ATPase and permease components, [Streptococcus sanguinis SK36]; multidrug ABC transporter ATPase 59549..61141 Streptococcus equi subsp. zooepidemicus MGCS10565 6761720 YP_002122444.1 CDS Sez_0048 NC_011134.1 61312 62433 D similar to ref|NP_815050.1| HesA/MoeB/ThiF family protein [Enterococcus faecalis V583]; HesA/MoeB/ThiF family protein 61312..62433 Streptococcus equi subsp. zooepidemicus MGCS10565 6761595 YP_002122445.1 CDS Sez_0049 NC_011134.1 62426 63601 D similar to ref|YP_196698.1| Hypothetical zinc protease [Ehrlichia ruminantium str. Gardel]; zinc protease 62426..63601 Streptococcus equi subsp. zooepidemicus MGCS10565 6761636 YP_002122446.1 CDS Sez_0050 NC_011134.1 63585 64448 R similar to ref|YP_140611.1| positive transcriptional regulator MutR family [Streptococcus thermophilus CNRZ1066]; positive transcriptional regulator, MutR family complement(63585..64448) Streptococcus equi subsp. zooepidemicus MGCS10565 6760886 YP_002122447.1 CDS Sez_0051 NC_011134.1 65062 65361 D hypothetical protein 65062..65361 Streptococcus equi subsp. zooepidemicus MGCS10565 6760888 YP_002122448.1 CDS thnsl NC_011134.1 65600 67075 D catalyzes the formation of L-threonine from O-phospho-L-homoserine; threonine synthase 65600..67075 Streptococcus equi subsp. zooepidemicus MGCS10565 6760889 YP_002122449.1 CDS Sez_0053 NC_011134.1 67115 67774 D similar to ref|YP_059409.1| Na+ driven multidrug efflux pump [Streptococcus pyogenes MGAS10394]; Multidrug efflux pump.; multi antimicrobial extrusion (MATE) family transporter 67115..67774 Streptococcus equi subsp. zooepidemicus MGCS10565 6761791 YP_002122450.1 CDS Sez_0054 NC_011134.1 67671 68417 D similar to ref|YP_059409.1| Na+ driven multidrug efflux pump [Streptococcus pyogenes MGAS10394]; Multidrug efflux pump.; multi antimicrobial extrusion (MATE) family transporter 67671..68417 Streptococcus equi subsp. zooepidemicus MGCS10565 6761693 YP_002122451.1 CDS rpsJ NC_011134.1 68797 69105 D NusE; involved in assembly of the 30S subunit; in the ribosome, this protein is involved in the binding of tRNA; in Escherichia coli this protein was also found to be involved in transcription antitermination; NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination; binding of NusB/S10 to boxA nucleates assembly of the antitermination complex; 30S ribosomal protein S10 68797..69105 Streptococcus equi subsp. zooepidemicus MGCS10565 6761772 YP_002122452.1 CDS rplC NC_011134.1 69403 70029 D binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin; 50S ribosomal protein L3 69403..70029 Streptococcus equi subsp. zooepidemicus MGCS10565 6761781 YP_002122453.1 CDS rplD NC_011134.1 70054 70677 D L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA; 50S ribosomal protein L4 70054..70677 Streptococcus equi subsp. zooepidemicus MGCS10565 6760700 YP_002122454.1 CDS rplW NC_011134.1 70725 70973 D similar to ref|NP_268462.1| 50S ribosomal protein L23 [Streptococcus pyogenes M1 GAS]; Binds to a specific region on the 23S rRNA.; 50S ribosomal protein L23 70725..70973 Streptococcus equi subsp. zooepidemicus MGCS10565 6760678 YP_002122455.1 CDS rplB NC_011134.1 70991 71824 D one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation; 50S ribosomal protein L2 70991..71824 Streptococcus equi subsp. zooepidemicus MGCS10565 6760415 YP_002122456.1 CDS rpsS NC_011134.1 71876 72214 D similar to gb|ABP89047.1| SSU ribosomal protein S19P [Streptococcus suis 05ZYH33]; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.; 30S ribosomal protein S19 71876..72214 Streptococcus equi subsp. zooepidemicus MGCS10565 6760417 YP_002122457.1 CDS rplV NC_011134.1 72230 72574 D binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center; 50S ribosomal protein L22 72230..72574 Streptococcus equi subsp. zooepidemicus MGCS10565 6760823 YP_002122458.1 CDS rpsC NC_011134.1 72587 73240 D forms a complex with S10 and S14; binds the lower part of the 30S subunit head and the mRNA in the complete ribosome to position it for translation; 30S ribosomal protein S3 72587..73240 Streptococcus equi subsp. zooepidemicus MGCS10565 6760690 YP_002122459.1 CDS rplP NC_011134.1 73244 73657 D located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e; 50S ribosomal protein L16 73244..73657 Streptococcus equi subsp. zooepidemicus MGCS10565 6760414 YP_002122460.1 CDS rpmC NC_011134.1 73667 73873 D one of the stabilizing components for the large ribosomal subunit; 50S ribosomal protein L29 73667..73873 Streptococcus equi subsp. zooepidemicus MGCS10565 6760364 YP_002122461.1 CDS rpsQ NC_011134.1 73901 74161 D primary binding protein; helps mediate assembly; involved in translation fidelity; 30S ribosomal protein S17 73901..74161 Streptococcus equi subsp. zooepidemicus MGCS10565 6760410 YP_002122462.1 CDS rplN NC_011134.1 74186 74554 D binds to the 23S rRNA between the centers for peptidyl transferase and GTPase; 50S ribosomal protein L14 74186..74554 Streptococcus equi subsp. zooepidemicus MGCS10565 6761683 YP_002122463.1 CDS rplX NC_011134.1 74638 74943 D assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel; 50S ribosomal protein L24 74638..74943 Streptococcus equi subsp. zooepidemicus MGCS10565 6761777 YP_002122464.1 CDS rplE NC_011134.1 74967 75509 D part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13; 50S ribosomal protein L5 74967..75509 Streptococcus equi subsp. zooepidemicus MGCS10565 6761797 YP_002122465.1 CDS rpsN NC_011134.1 75525 75710 D located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group appear to contain the zinc-binding motif; 30S ribosomal protein S14 75525..75710 Streptococcus equi subsp. zooepidemicus MGCS10565 6760892 YP_002122466.1 CDS rpsH NC_011134.1 76043 76441 D binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; 30S ribosomal protein S8 76043..76441 Streptococcus equi subsp. zooepidemicus MGCS10565 6761774 YP_002122467.1 CDS rplF NC_011134.1 76763 77299 D ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance; 50S ribosomal protein L6 76763..77299 Streptococcus equi subsp. zooepidemicus MGCS10565 6761701 YP_002122468.1 CDS rplR NC_011134.1 77393 77758 D binds 5S rRNA along with protein L5 and L25; 50S ribosomal protein L18 77393..77758 Streptococcus equi subsp. zooepidemicus MGCS10565 6760893 YP_002122469.1 CDS rpsE NC_011134.1 77777 78271 D located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance; 30S ribosomal protein S5 77777..78271 Streptococcus equi subsp. zooepidemicus MGCS10565 6760898 YP_002122470.1 CDS rpmD NC_011134.1 78286 78468 D L30 binds domain II of the 23S rRNA and the 5S rRNA; similar to eukaryotic protein L7; 50S ribosomal protein L30 78286..78468 Streptococcus equi subsp. zooepidemicus MGCS10565 6760897 YP_002122471.1 CDS rplO NC_011134.1 78670 79110 D late assembly protein; 50S ribosomal protein L15 78670..79110 Streptococcus equi subsp. zooepidemicus MGCS10565 6760890 YP_002122472.1 CDS secY NC_011134.1 79127 80431 D forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase; preprotein translocase subunit SecY 79127..80431 Streptococcus equi subsp. zooepidemicus MGCS10565 6760896 YP_002122473.1 CDS adk NC_011134.1 80472 81224 D similar to ref|ZP_01834380.1| adenylate kinase [Streptococcus pneumoniae SP23-BS72]; This small ubiquitous enzyme is essential for maintenance and cell growth.; adenylate kinase 80472..81224 Streptococcus equi subsp. zooepidemicus MGCS10565 6760891 YP_002122474.1 CDS infA NC_011134.1 81288 81560 D stimulates the activities of the other two initiation factors, IF-2 and IF-3; translation initiation factor IF-1 81288..81560 Streptococcus equi subsp. zooepidemicus MGCS10565 6760887 YP_002122475.1 CDS rpmJ NC_011134.1 81586 81702 D smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group have the motif; 50S ribosomal protein L36 81586..81702 Streptococcus equi subsp. zooepidemicus MGCS10565 6760361 YP_002122476.1 CDS rpsM NC_011134.1 81720 82085 D located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA; 30S ribosomal protein S13 81720..82085 Streptococcus equi subsp. zooepidemicus MGCS10565 6760681 YP_002122477.1 CDS rpsK NC_011134.1 82103 82486 D located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3; 30S ribosomal protein S11 82103..82486 Streptococcus equi subsp. zooepidemicus MGCS10565 6760849 YP_002122478.1 CDS rpoA NC_011134.1 82533 83471 D catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme; DNA-directed RNA polymerase subunit alpha 82533..83471 Streptococcus equi subsp. zooepidemicus MGCS10565 6760512 YP_002122479.1 CDS rplQ NC_011134.1 83486 83872 D is a component of the macrolide binding site in the peptidyl transferase center; 50S ribosomal protein L17 83486..83872 Streptococcus equi subsp. zooepidemicus MGCS10565 6761745 YP_002122480.1 CDS Sez_0084 NC_011134.1 85192 85986 D similar to ref|YP_850136.1| hypothetical protein lwe1939 [Listeria welshimeri serovar 6b str. SLCC5334]; hypothetical protein 85192..85986 Streptococcus equi subsp. zooepidemicus MGCS10565 6760894 YP_002122481.1 CDS Sez_0085 NC_011134.1 85983 86759 D similar to ref|XP_597510.3| Gene info PREDICTED: similar to olfactory receptor MOR123-1 [Bos taurus]; hypothetical protein 85983..86759 Streptococcus equi subsp. zooepidemicus MGCS10565 6761755 YP_002122482.1 CDS Sez_0086 NC_011134.1 86749 87438 D similar to gb|EDK97023.1| Gene info phosphoinositide-3-kinase, class 3, isoform CRA_c [Mus musculus]; hypothetical protein 86749..87438 Streptococcus equi subsp. zooepidemicus MGCS10565 6761804 YP_002122483.1 CDS Sez_0087 NC_011134.1 87471 87623 D hypothetical protein 87471..87623 Streptococcus equi subsp. zooepidemicus MGCS10565 6761689 YP_002122484.1 CDS Sez_0088 NC_011134.1 87644 87937 D similar to ref|YP_001449395.1| hypothetical protein SGO_0073 [Streptococcus gordonii str. Challis substr. CH1]; hypothetical protein 87644..87937 Streptococcus equi subsp. zooepidemicus MGCS10565 6760437 YP_002122485.1 CDS int NC_011134.1 94623 95756 R similar to ref|YP_001197470.1| hypothetical protein SSU05_0100 [Streptococcus suis 05ZYH33]; Site-specific DNA recombination.; integrase complement(94623..95756) Streptococcus equi subsp. zooepidemicus MGCS10565 6760848 YP_002122486.1 CDS Sez_0090 NC_011134.1 95746 95952 R similar to ref|YP_001197471.1| hypothetical protein SSU05_0101 [Streptococcus suis 05ZYH33]; hypothetical protein complement(95746..95952) Streptococcus equi subsp. zooepidemicus MGCS10565 6762181 YP_002122487.1 CDS Sez_0091 NC_011134.1 96013 96843 R similar to ref|YP_001197472.1| hypothetical protein SSU05_0102 [Streptococcus suis 05ZYH33]; Unknown, COG2946 phage replication protein RstA.; Cro/CI family transcriptional regulator complement(96013..96843) Streptococcus equi subsp. zooepidemicus MGCS10565 6760634 YP_002122488.1 CDS Sez_0092 NC_011134.1 97034 97441 R similar to ref|YP_001197473.1| hypothetical protein SSU05_0103 [Streptococcus suis 05ZYH33]; hypothetical protein complement(97034..97441) Streptococcus equi subsp. zooepidemicus MGCS10565 6760902 YP_002122489.1 CDS Sez_0093 NC_011134.1 97730 99139 R similar to ref|YP_893172.1| FtsK/SpoIIIE family protein [Bacillus thuringiensis str. Al Hakam]; Unknown, COG1674 DNA segregation ATPase FtsK/SpoIIIE and related proteins.; DNA translocase FtsK complement(97730..99139) Streptococcus equi subsp. zooepidemicus MGCS10565 6760633 YP_002122490.1 CDS Sez_0094 NC_011134.1 99857 100225 R similar to ref|NP_073692.1| tail protein [Bacillus phage GA-1]; hypothetical protein complement(99857..100225) Streptococcus equi subsp. zooepidemicus MGCS10565 6762254 YP_002122491.1 CDS Sez_0095 NC_011134.1 100620 101180 R similar to ref|ZP_01829310.1| IS1167, transposase [Streptococcus pneumoniae SP18-BS74]; transposase IS1167 complement(100620..101180) Streptococcus equi subsp. zooepidemicus MGCS10565 6760632 YP_002122492.1 CDS Sez_0096 NC_011134.1 101346 101813 R similar to ref|ZP_01829310.1| IS1167, transposase [Streptococcus pneumoniae SP18-BS74]; transposase IS1193D-like complement(101346..101813) Streptococcus equi subsp. zooepidemicus MGCS10565 6760903 YP_002122493.1 CDS Sez_0098 NC_011134.1 102187 103392 R similar to ref|YP_078429.1| Major facilitator superfamily [Bacillus licheniformis ATCC 14580]; Unknown, COG0477 Permeases of the major facilitator superfamily.; macrolide efflux protein complement(102187..103392) Streptococcus equi subsp. zooepidemicus MGCS10565 6760905 YP_002122494.1 CDS sclZ.1 NC_011134.1 103744 105030 D similar to gb|ABA41499.1| collagen-like protein I [Streptococcus equi subsp. equi]; Possible adhesin, has a collagen-structural-motif domain composed of 83 Gly-Xaa-Yaa repeats that in part form 22 GDQ-GQK-GER repeats.; hypothetical protein 103744..105030 Streptococcus equi subsp. zooepidemicus MGCS10565 6760629 YP_002122495.1 CDS sclZ.2 NC_011134.1 105157 106308 D similar to gb|ABA41497.1| collagen-like protein G [Streptococcus equi subsp. equi]; Possible adhesin, has a collagen-structural-motif domain composed of 67 Gly-Xaa-Yaa repeats.; hypothetical protein 105157..106308 Streptococcus equi subsp. zooepidemicus MGCS10565 6762225 YP_002122496.1 CDS Sez_0101 NC_011134.1 106820 107344 D similar to ref|ZP_01372633.1| NUDIX hydrolase [Desulfitobacterium hafniense DCB-2]; Catalyzes The 1,3-Allylic Rearrangement Of The Homoallylic Substrate Isopentenyl (Ipp) To Its Highly Electrophilic Allylic Isomer, Dimethylallyl Diphosphate (Dmapp).; nudix hydrolase 106820..107344 Streptococcus equi subsp. zooepidemicus MGCS10565 6760628 YP_002122497.1 CDS ipk NC_011134.1 107558 108409 D An essential enzyme in the nonmevalonate pathway of isopentenyl diphosphate and dimethylallyl diphosphate biosynthesis; 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase 107558..108409 Streptococcus equi subsp. zooepidemicus MGCS10565 6762145 YP_002122498.1 CDS adcR NC_011134.1 108479 108922 D similar to ref|YP_059444.1| High-affinity zinc uptake system ATP-binding protein [Streptococcus pyogenes MGAS10394]; Unknown, COG1846 Transcriptional regulators.; transcriptional repressor AdcR for Zn(2+)-responsive expression 108479..108922 Streptococcus equi subsp. zooepidemicus MGCS10565 6760627 YP_002122499.1 CDS znuC NC_011134.1 108941 109645 D similar to ref|YP_059444.1| High-affinity zinc uptake system ATP-binding protein [Streptococcus pyogenes MGAS10394]; Part of the ATP-driven transport system for zinc.; zinc ABC transporter ATP-binding protein ZnuC 108941..109645 Streptococcus equi subsp. zooepidemicus MGCS10565 6762252 YP_002122500.1 CDS znuB NC_011134.1 109614 110447 D similar to ref|YP_279546.1| high-affinity zinc uptake system membrane protein [Streptococcus pyogenes MGAS6180]; Part of an ATP-driven transport system for zinc.; Zinc ABC transporter inner membrane permease ZnuB 109614..110447 Streptococcus equi subsp. zooepidemicus MGCS10565 6760626 YP_002122501.1 CDS tyrS NC_011134.1 110629 111885 R catalyzes the formation of tyrosyl-tRNA(Tyr) from tyrosine and tRNA(Tyr); tyrosyl-tRNA synthetase complement(110629..111885) Streptococcus equi subsp. zooepidemicus MGCS10565 6760906 YP_002122502.1 CDS pbpZ NC_011134.1 111990 114290 D similar to ref|NP_663878.1| penicillin-binding protein 1b [Streptococcus pyogenes MGAS315]; CSynthesis and cross-linking of nascent peptidoglycan glycan strands.; multimodular transpeptidase-transglycosylase 111990..114290 Streptococcus equi subsp. zooepidemicus MGCS10565 6760625 YP_002122503.1 CDS rpoB NC_011134.1 114552 118118 D DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme; DNA-directed RNA polymerase subunit beta 114552..118118 Streptococcus equi subsp. zooepidemicus MGCS10565 6762262 YP_002122504.1 CDS rpoC NC_011134.1 118236 121844 D DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Subunit beta' binds to sigma factor allowing it to bind to the -10 region of the promoter; DNA-directed RNA polymerase subunit beta' 118236..121844 Streptococcus equi subsp. zooepidemicus MGCS10565 6760624 YP_002122505.1 CDS Sez_0110 NC_011134.1 122411 122965 D similar to ref|ZP_01803959.1| hypothetical protein CdifQ_04001361 [Clostridium difficile QCD-32g58]; Unknown, Gene is flanked 5' and 3' by a 51 nt direct repeat (aggagctagtcttagctccttttatcatgctaaaatcattagattaattgg) and small ORFs with similarity to IS1193D.; hypothetical protein 122411..122965 Streptococcus equi subsp. zooepidemicus MGCS10565 6762273 YP_002122506.1 CDS alr NC_011134.1 123518 124576 D similar to ref|NP_736373.1| hypothetical protein gbs1940 [Streptococcus agalactiae NEM316]; Alanine racemase catalyses the pyridoxal-dependent conversion of L-alanine into D-alanine, a key component of bacterial peptidoglycan.; alanine racemase 123518..124576 Streptococcus equi subsp. zooepidemicus MGCS10565 6760623 YP_002122507.1 CDS Sez_0112 NC_011134.1 124637 125002 D similar to ref|NP_268497.1| DNA binding protein [Streptococcus pyogenes M1 GAS]; Unknown, COG4699: Uncharacterized protein conserved in bacteria.; hypothetical protein 124637..125002 Streptococcus equi subsp. zooepidemicus MGCS10565 6762246 YP_002122508.1 CDS Sez_0113 NC_011134.1 125535 127538 D similar to ref|YP_001450417.1| bacteriocin-associated integral membrane protein subfamily [Streptococcus gordonii str. Challis substr. CH1]; Unknown, bacteriocin associated membrane protein; immunity protein.; immunity protein 125535..127538 Streptococcus equi subsp. zooepidemicus MGCS10565 6760622 YP_002122509.1 CDS Sez_0114 NC_011134.1 127540 128208 D similar to ref|ZP_01835894.1| ABC transporter, ATP-binding protein [Streptococcus pneumoniae SP23-BS72]; Probably part of a binding-protein-dependent transport system for an amino acid. Probably responsible for energy coupling to the transport system; competence damage-inducible protein A.; ABC transporter ATP-binding protein 127540..128208 Streptococcus equi subsp. zooepidemicus MGCS10565 6762242 YP_002122510.1 CDS comGA NC_011134.1 128366 129304 D similar to ref|YP_595819.1| ComG operon protein 1 [Streptococcus pyogenes MGAS9429]; Required for uptake of DNA by competent cells.; late competence protein ComGA 128366..129304 Streptococcus equi subsp. zooepidemicus MGCS10565 6760621 YP_002122511.1 CDS comGB NC_011134.1 129180 130271 D similar to ref|YP_281451.1| comG operon protein 2 [Streptococcus pyogenes MGAS5005]; Required for transformation and DNA binding.; late competence protein ComGB 129180..130271 Streptococcus equi subsp. zooepidemicus MGCS10565 6762248 YP_002122512.1 CDS comGC NC_011134.1 130272 130595 D similar to ref|YP_601589.1| ComG operon protein 3 [Streptococcus pyogenes MGAS10750]; Involved in competence.; late competence protein ComGC 130272..130595 Streptococcus equi subsp. zooepidemicus MGCS10565 6760620 YP_002122513.1 CDS comGD NC_011134.1 130573 130998 D similar to ref|NP_663885.1| competence protein [Streptococcus pyogenes MGAS315]; Involved in competence.; late competence protein ComGD 130573..130998 Streptococcus equi subsp. zooepidemicus MGCS10565 6760909 YP_002122514.1 CDS comGF NC_011134.1 131158 131667 D similar to ref|YP_281455.1| comG operon protein 6 [Streptococcus pyogenes MGAS5005]; Involved in competence.; competence protein ComG 131158..131667 Streptococcus equi subsp. zooepidemicus MGCS10565 6760619 YP_002122515.1 CDS comGF NC_011134.1 131645 132007 D similar to ref|YP_059458.1| ComG operon protein 6 [Streptococcus pyogenes MGAS10394]; Involved in competence.; late competence protein ComGG 131645..132007 Streptococcus equi subsp. zooepidemicus MGCS10565 6762292 YP_002122516.1 CDS Sez_0121 NC_011134.1 132053 132856 R similar to ref|NP_268574.1| transposase, IS861 [Streptococcus pyogenes M1 GAS]; transposase IS861 orfB complement(132053..132856) Streptococcus equi subsp. zooepidemicus MGCS10565 6760618 YP_002122517.1 CDS Sez_0122 NC_011134.1 132880 133395 R similar to ref|YP_602677.1| Transposase [Streptococcus pyogenes MGAS10750]; transposase IS861 orfA complement(132880..133395) Streptococcus equi subsp. zooepidemicus MGCS10565 6762096 YP_002122518.1 CDS Sez_0123 NC_011134.1 133501 134454 D similar to ref|YP_595826.1| adenine-specific methyltransferase [Streptococcus pyogenes MGAS9429]; Unknown, COG0827 Adenine-specific DNA methylase.; adenine-specific methyltransferase 133501..134454 Streptococcus equi subsp. zooepidemicus MGCS10565 6760617 YP_002122519.1 CDS ackA NC_011134.1 134514 135716 D AckA utilizes acetate and can acetylate CheY which increases signal strength during flagellar rotation; utilizes magnesium and ATP; also involved in conversion of acetate to aceyl-CoA; acetate kinase 134514..135716 Streptococcus equi subsp. zooepidemicus MGCS10565 6762257 YP_002122520.1 CDS Sez_0125 NC_011134.1 136088 136702 R similar to ref|ZP_01817412.1| hypothetical protein CGSSp3BS71_02812 [Streptococcus pneumoniae SP3-BS71]; hypothetical protein complement(136088..136702) Streptococcus equi subsp. zooepidemicus MGCS10565 6760616 YP_002122521.1 CDS Sez_0126 NC_011134.1 137231 139273 D similar to ref|ZP_00784694.1| transcriptional antiterminator, BglG family [Streptococcus agalactiae COH1]; Transcriptional antiterminator.; BglG family transcriptional regulator 137231..139273 Streptococcus equi subsp. zooepidemicus MGCS10565 6760914 YP_002122522.1 CDS Sez_0127 NC_011134.1 139275 139562 D similar to ref|NP_687232.1| PTS system, IIB component, [Streptococcus agalactiae 2603V/R]; Probably involved in ascorbate uptake.; sugar phosphotransferase component II B 139275..139562 Streptococcus equi subsp. zooepidemicus MGCS10565 6760615 YP_002122523.1 CDS ulaA NC_011134.1 139575 140918 D membrane component; functions with enzymes IIB (sgaB; ulaB) and IIA (sgaA; ulaC) enzyme I and HPr for anaerobic utilization and uptake of L-ascorbate; sgaTBA are regulated by yifQ as well as Crp and Fnr; PTS system ascorbate-specific transporter subunit IIC 139575..140918 Streptococcus equi subsp. zooepidemicus MGCS10565 6760917 YP_002122524.1 CDS Sez_0131 NC_011134.1 142912 143034 D hypothetical protein 142912..143034 Streptococcus equi subsp. zooepidemicus MGCS10565 6760913 YP_002122525.1 CDS pepO NC_011134.1 143257 145152 D similar to ref|YP_597524.1| oligoendopeptidase O [Streptococcus pyogenes MGAS9429]; Unknown, COG3590 Predicted metalloendopeptidase.; metallopeptidase PepO 143257..145152 Streptococcus equi subsp. zooepidemicus MGCS10565 6760612 YP_002122526.1 CDS tsf NC_011134.1 145352 146407 R EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu; elongation factor Ts complement(145352..146407) Streptococcus equi subsp. zooepidemicus MGCS10565 6760912 YP_002122527.1 CDS rpsB NC_011134.1 146560 147315 R one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit; 30S ribosomal protein S2 complement(146560..147315) Streptococcus equi subsp. zooepidemicus MGCS10565 6760611 YP_002122528.1 CDS ahpC NC_011134.1 149343 149903 R similar to ref|NP_270011.1| alkyl hydroperoxidase [Streptococcus pyogenes M1 GAS]; Directly reduces organic hydroperoxides in its reduced dithiol form.; alkyl hydroperoxide reductase complement(149343..149903) Streptococcus equi subsp. zooepidemicus MGCS10565 6760610 YP_002122529.1 CDS cspA NC_011134.1 150535 150738 D similar to ref|NP_270010.1| cold shock protein [Streptococcus pyogenes M1 GAS]; Stimulates the transcription of cold-shock-inducible promoters.; cold-shock protein 150535..150738 Streptococcus equi subsp. zooepidemicus MGCS10565 6760859 YP_002122530.1 CDS ctsR NC_011134.1 150910 151371 D similar to ref|YP_599441.1| CtsR family transcriptional regulator [Streptococcus pyogenes MGAS10270]; Negative regulator of class III stress genes (clpC, clpP).; CtsR family transcriptional regulator 150910..151371 Streptococcus equi subsp. zooepidemicus MGCS10565 6760609 YP_002122531.1 CDS clpC NC_011134.1 151392 153812 D similar to ref|YP_603351.1| Negative regulator of genetic competence clpC/mecB [Streptococcus pyogenes MGAS10750]; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with dnaK, dnaJ and grpE. Acts before dnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of clpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by dnaK.; ATP-dependent Clp protease ATP-binding subunit 151392..153812 Streptococcus equi subsp. zooepidemicus MGCS10565 6760924 YP_002122532.1 CDS Sez_0141 NC_011134.1 154581 155012 D similar to ref|NP_688051.1| hypothetical protein SAG1041 [Streptococcus agalactiae 2603V/R]; hypothetical protein 154581..155012 Streptococcus equi subsp. zooepidemicus MGCS10565 6760608 YP_002122533.1 CDS Sez_0142 NC_011134.1 155044 156303 D similar to ref|ZP_00874485.1| Lipase, class 3 [Streptococcus suis 89/1591]; Unknown, has lipase class 3 domain.; hypothetical protein 155044..156303 Streptococcus equi subsp. zooepidemicus MGCS10565 6760920 YP_002122534.1 CDS Sez_0143 NC_011134.1 156309 156677 D similar to ref|ZP_00874484.1| hypothetical protein SsuiDRAFT_1541 [Streptococcus suis 89/1591]; hypothetical protein 156309..156677 Streptococcus equi subsp. zooepidemicus MGCS10565 6760607 YP_002122535.1 CDS Sez_0144 NC_011134.1 156658 156948 D similar to ref|ZP_00874545.1| hypothetical protein SsuiDRAFT_1602 [Streptococcus suis 89/1591]; hypothetical protein 156658..156948 Streptococcus equi subsp. zooepidemicus MGCS10565 6762302 YP_002122536.1 CDS groES NC_011134.1 157248 157535 D 10 kDa chaperonin; Cpn10; GroES; forms homoheptameric ring; binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it; folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES; release of the folded substrate is dependent on ATP binding and hydrolysis in the trans ring; co-chaperonin GroES 157248..157535 Streptococcus equi subsp. zooepidemicus MGCS10565 6760606 YP_002122537.1 CDS groEL NC_011134.1 157603 159228 D 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth; molecular chaperone GroEL 157603..159228 Streptococcus equi subsp. zooepidemicus MGCS10565 6760931 YP_002122538.1 CDS Sez_0147 NC_011134.1 159562 160032 R similar to ref|YP_001450297.1| Phosphohydrolase (MutT/nudix family protein) [Streptococcus gordonii str. Challis substr. CH1]; MutT/nudix family protein complement(159562..160032) Streptococcus equi subsp. zooepidemicus MGCS10565 6760605 YP_002122539.1 CDS Sez_0148 NC_011134.1 160339 160665 D similar to ref|ZP_01824093.1| hypothetical protein CGSSp9BS68_00132 [Streptococcus pneumoniae SP9-BS68]; hypothetical protein 160339..160665 Streptococcus equi subsp. zooepidemicus MGCS10565 6760934 YP_002122540.1 CDS Sez_0149 NC_011134.1 160675 161814 D similar to ref|ZP_01824094.1| hypothetical protein CGSSp9BS68_00137 [Streptococcus pneumoniae SP9-BS68]; hypothetical protein 160675..161814 Streptococcus equi subsp. zooepidemicus MGCS10565 6760604 YP_002122541.1 CDS Sez_0150 NC_011134.1 162290 162877 D similar to ref|ZP_01824096.1| ATPase [Streptococcus pneumoniae SP9-BS68]; Part ABC transporter complex.; Nod factor export ATP-binding protein I (Nodulation ATP-binding protein I) 162290..162877 Streptococcus equi subsp. zooepidemicus MGCS10565 6762322 YP_002122542.1 CDS Sez_0151 NC_011134.1 162874 163356 D similar to ref|ZP_01819232.1| hypothetical protein CGSSp6BS73_09666 [Streptococcus pneumoniae SP6-BS73]; hypothetical protein 162874..163356 Streptococcus equi subsp. zooepidemicus MGCS10565 6760603 YP_002122543.1 CDS Sez_0152 NC_011134.1 163381 163896 D similar to ref|ZP_01819367.1| succinyl-diaminopimelate desuccinylase [Streptococcus pneumoniae SP6-BS73]; hypothetical protein 163381..163896 Streptococcus equi subsp. zooepidemicus MGCS10565 6762327 YP_002122544.1 CDS Sez_0153 NC_011134.1 164530 166164 D similar to ref|NP_608080.1| hypothetical protein spyM18_2125 [Streptococcus pyogenes MGAS8232]; hypothetical protein 164530..166164 Streptococcus equi subsp. zooepidemicus MGCS10565 6760602 YP_002122545.1 CDS yhcT NC_011134.1 166305 167198 R similar to ref|NP_722253.1| pseudouridylate synthase [Streptococcus mutans UA159]; Responsible For Synthesis Of Pseudouridine From Uracil At Positions 955, 2504 And 2580 In 23s Ribosomal RNA.; ribosomal large subunit pseudouridine synthase D complement(166305..167198) Streptococcus equi subsp. zooepidemicus MGCS10565 6760932 YP_002122546.1 CDS Sez_0155 NC_011134.1 167182 167379 R similar to ref|NP_665564.1| hypothetical protein SpyM3_1760 [Streptococcus pyogenes MGAS315]; hypothetical protein complement(167182..167379) Streptococcus equi subsp. zooepidemicus MGCS10565 6760601 YP_002122547.1 CDS Sez_0156 NC_011134.1 167608 169350 D similar to ref|NP_688485.1| hypothetical protein SAG1491 [Streptococcus agalactiae 2603V/R]; S-layer protein 167608..169350 Streptococcus equi subsp. zooepidemicus MGCS10565 6760928 YP_002122548.1 CDS Sez_0157 NC_011134.1 169491 169871 D similar to ref|ZP_00365970.1| COG0251: translation initiation inhibitor, yjgF family [Streptococcus pyogenes M49 591]; translation initiation inhibitor 169491..169871 Streptococcus equi subsp. zooepidemicus MGCS10565 6760600 YP_002122549.1 CDS Sez_0158 NC_011134.1 169909 172230 D similar to ref|YP_061071.1| Multimodular transpeptidase-transglycosylase PBP 2A [Streptococcus pyogenes MGAS10394]; Cell wall formation. May be involved in outgrowth of the germinated spore or it could function in the synthesis of the germ cell wall.; multimodular transpeptidase-transglycosylase 169909..172230 Streptococcus equi subsp. zooepidemicus MGCS10565 6760938 YP_002122550.1 CDS secE NC_011134.1 172443 172619 D forms a complex with SecY and SecG; SecYEG forms a protein-conducting channel to which secA binds and translocates targeted polypeptides across the cytoplasmic membrane, a process driven by ATP and a proton-motive force; preprotein translocase subunit SecE 172443..172619 Streptococcus equi subsp. zooepidemicus MGCS10565 6760598 YP_002122551.1 CDS nusG NC_011134.1 173010 173555 D Modulates Rho-dependent transcription termination; transcription antitermination protein NusG 173010..173555 Streptococcus equi subsp. zooepidemicus MGCS10565 6762279 YP_002122552.1 CDS Sez_0161 NC_011134.1 173544 173666 R hypothetical protein complement(173544..173666) Streptococcus equi subsp. zooepidemicus MGCS10565 6760599 YP_002122553.1 CDS sclZ.3 NC_011134.1 174028 175035 D similar to gb|ABA41496.1| collagen-like protein F [Streptococcus equi subsp. equi]; Possible adhesin, has a collagen-structural-motif domain composed of 55 Gly-Xaa-Yaa repeats.; hypothetical protein 174028..175035 Streptococcus equi subsp. zooepidemicus MGCS10565 6762288 YP_002122554.1 CDS mgaZ NC_011134.1 175795 177312 D similar to emb|CAB65412.1| Mga-like regulatory protein [Streptococcus dysgalactiae subsp. dysgalactiae]; positive regulator of the adjacent M-like protein.; M protein trans-acting positive regulator 175795..177312 Streptococcus equi subsp. zooepidemicus MGCS10565 6760597 YP_002122555.1 CDS spaZ NC_011134.1 177487 178665 D similar to gb|AAB71984.1| M-protein [Streptococcus equi]; Binds IgG molecules of the Ig1, Ig2 and Ig4 subclasses, and also binds fibrinogen.; protective antigen-like protein, fibrinogen- and Ig-binding protein precursor 177487..178665 Streptococcus equi subsp. zooepidemicus MGCS10565 6760937 YP_002122556.1 CDS Sez_0165 NC_011134.1 178713 178874 R hypothetical protein complement(178713..178874) Streptococcus equi subsp. zooepidemicus MGCS10565 6760596 YP_002122557.1 CDS leuS NC_011134.1 179254 181755 D leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase; leucyl-tRNA synthetase 179254..181755 Streptococcus equi subsp. zooepidemicus MGCS10565 6760936 YP_002122558.1 CDS Sez_0167 NC_011134.1 181942 182286 D similar to ref|NP_268734.1| hypothetical protein SPy_0435 [Streptococcus pyogenes M1 GAS]; hypothetical protein 181942..182286 Streptococcus equi subsp. zooepidemicus MGCS10565 6760595 YP_002122559.1 CDS ulaA NC_011134.1 182494 183927 D membrane component; functions with enzymes IIB (sgaB; ulaB) and IIA (sgaA; ulaC) enzyme I and HPr for anaerobic utilization and uptake of L-ascorbate; sgaTBA are regulated by yifQ as well as Crp and Fnr; PTS system ascorbate-specific transporter subunit IIC 182494..183927 Streptococcus equi subsp. zooepidemicus MGCS10565 6762285 YP_002122560.1 CDS sgaB NC_011134.1 184043 184321 D similar to ref|NP_268554.1| hypothetical protein SPy_0175 [Streptococcus pyogenes M1 GAS]; The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. This system is involved in ascorbate transport.; PTS system 3-keto-L-gulonate/L-ascorbate specific transporter subunit IIB (SgaB) 184043..184321 Streptococcus equi subsp. zooepidemicus MGCS10565 6760594 YP_002122561.1 CDS sgaC NC_011134.1 184538 185023 D similar to ref|YP_601650.1| PTS system, 3-keto-L-gulonate specific IIA component [Streptococcus pyogenes MGAS10750]; The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. This system is involved in ascorbate transport.; ascorbate-specific phosphotransferase enzyme IIA component 184538..185023 Streptococcus equi subsp. zooepidemicus MGCS10565 6760940 YP_002122562.1 CDS ulaD NC_011134.1 185121 185783 D catalyzes the formation of L-xylulose-5-phosphate from 3-keto-L-gulonate-6-phosphate in anaerobic L-ascorbate utilization; 3-keto-L-gulonate-6-phosphate decarboxylase 185121..185783 Streptococcus equi subsp. zooepidemicus MGCS10565 6760593 YP_002122563.1 CDS sgaU NC_011134.1 185683 186651 D L-xylulose 5-phosphate 3-epimerase activity not yet demonstrated; may be involved in the utilization of 2,3-diketo-L-gulonate; L-xylulose 5-phosphate 3-epimerase 185683..186651 Streptococcus equi subsp. zooepidemicus MGCS10565 6760916 YP_002122564.1 CDS araD NC_011134.1 186652 187368 D catalyzes the formation of D-xylulose 5-phosphate from L-ribulose 5-phosphate in the L-arabinose and L-ascorbate degradation pathways; L-ribulose-5-phosphate 4-epimerase 186652..187368 Streptococcus equi subsp. zooepidemicus MGCS10565 6760592 YP_002122565.1 CDS Sez_0174 NC_011134.1 187665 189317 D similar to ref|YP_059519.1| Transcription antiterminator, BglG family [Streptococcus pyogenes MGAS10394]; regulator of adjacent sga operon.; transcriptional antiterminator with PTS regulation domain 187665..189317 Streptococcus equi subsp. zooepidemicus MGCS10565 6760943 YP_002122566.1 CDS sgaG NC_011134.1 189512 190603 D similar to ref|YP_601656.1| L-ascorbate 6-phosphate lactonase [Streptococcus pyogenes MGAS10750]; Proposed to catalyze the first step in L-ascorbate-6-phosphate degradation.; L-ascorbate 6-phosphate lactonase 189512..190603 Streptococcus equi subsp. zooepidemicus MGCS10565 6760591 YP_002122567.1 CDS Sez_0176 NC_011134.1 190738 190914 D hypothetical protein 190738..190914 Streptococcus equi subsp. zooepidemicus MGCS10565 6760942 YP_002122568.1 CDS opuAA NC_011134.1 191114 192310 D similar to ref|NP_268562.1| glycine betaine/proline ABC transporter (ATP-binding protein) [Streptococcus pyogenes M1 GAS]; Involved in a multicomponent binding-protein-dependent transport system for glycine betaine. Probably responsible for energy coupling to the transport system.; glycine betaine transport ATP-binding protein OpuAA 191114..192310 Streptococcus equi subsp. zooepidemicus MGCS10565 6760589 YP_002122569.1 CDS opuAB NC_011134.1 192328 194058 D similar to ref|YP_601658.1| Glycine betaine-binding protein / Glycine betaine transport system permease [Streptococcus pyogenes MGAS10750]; Involved in a multicomponent binding-protein-dependent transport system for glycine betaine; probably responsible for the translocation of the substrate across the membrane.; glycine betaine transport system permease OpuAB 192328..194058 Streptococcus equi subsp. zooepidemicus MGCS10565 6760951 YP_002122570.1 CDS Sez_0179 NC_011134.1 194284 194433 R hypothetical protein complement(194284..194433) Streptococcus equi subsp. zooepidemicus MGCS10565 6760588 YP_002122571.1 CDS Sez_0180 NC_011134.1 194597 196318 D similar to ref|ZP_01371554.1| transposase, IS4 [Desulfitobacterium hafniense DCB-2]; transposase IS4-like 194597..196318 Streptococcus equi subsp. zooepidemicus MGCS10565 6762308 YP_002122572.1 CDS Sez_0181 NC_011134.1 196423 196572 R hypothetical protein complement(196423..196572) Streptococcus equi subsp. zooepidemicus MGCS10565 6760587 YP_002122573.1 CDS polA NC_011134.1 196567 199266 D has 3'-5' exonuclease, 5'-3' exonuclease and 5'-3'polymerase activities, primarily functions to fill gaps during DNA replication and repair; DNA polymerase I 196567..199266 Streptococcus equi subsp. zooepidemicus MGCS10565 6760950 YP_002122574.1 CDS Sez_0183 NC_011134.1 199687 200139 D similar to ref|YP_597771.1| CoA binding protein [Streptococcus pyogenes MGAS10270]; Unknown, COG1832 Predicted CoA-binding protein.; succinyl-CoA synthetase subunit alpha 199687..200139 Streptococcus equi subsp. zooepidemicus MGCS10565 6760586 YP_002122575.1 CDS furR NC_011134.1 200176 200649 D similar to ref|YP_279628.1| ferric uptake regulation protein [Streptococcus pyogenes MGAS6180]; Regulation of ferric uptake.; Ferric uptake regulator Fur 200176..200649 Streptococcus equi subsp. zooepidemicus MGCS10565 6760947 YP_002122576.1 CDS Sez_0185 NC_011134.1 201010 202689 D immunoglobulin G binding protein G precursor; similar to gb|AAQ08491.1| Szp protein [Streptococcus equi subsp. zooepidemicus]; Unknown, possibly involved in immune evasion; antiphagocytic M-like protein 201010..202689 Streptococcus equi subsp. zooepidemicus MGCS10565 6760584 YP_002122577.1 CDS Sez_0186 NC_011134.1 202803 206783 D similar to dbj|BAF34922.1| dextran-binding lectin A [Streptococcus sobrinus]; Catalysis of the hydrolysis of terminal, non-reducing alpha-D-galactose residues in alpha-D-galactosides, including galactose oligosaccharides, galactomannans and galactohydrolase.; alpha-galactosidase 202803..206783 Streptococcus equi subsp. zooepidemicus MGCS10565 6760949 YP_002122578.1 CDS Sez_0187 NC_011134.1 206978 207823 R similar to ref|ZP_00365478.1| COG5523: Predicted integral membrane protein [Streptococcus pyogenes M49 591]; hypothetical protein complement(206978..207823) Streptococcus equi subsp. zooepidemicus MGCS10565 6760582 YP_002122579.1 CDS Sez_0188 NC_011134.1 207856 207999 R hypothetical protein complement(207856..207999) Streptococcus equi subsp. zooepidemicus MGCS10565 6760921 YP_002122580.1 CDS tgt NC_011134.1 207978 209186 D Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr); queuine tRNA-ribosyltransferase 207978..209186 Streptococcus equi subsp. zooepidemicus MGCS10565 6760581 YP_002122581.1 CDS sclZ.4 NC_011134.1 209617 211005 D similar to gb|AAQ91576.1| collagen-like protein 3 [Streptococcus equi]; Specific Function:Possible adhesin, has a collagen-structural-motif domain composed of 79 Gly-Xaa-Yaa repeats.; hypothetical protein 209617..211005 Streptococcus equi subsp. zooepidemicus MGCS10565 6760953 YP_002122582.1 CDS Sez_0191 NC_011134.1 212394 212705 D similar to ref|YP_281540.1| zinc finger protein [Streptococcus pyogenes MGAS5005]; zinc finger protein 212394..212705 Streptococcus equi subsp. zooepidemicus MGCS10565 6760580 YP_002122583.1 CDS bioY NC_011134.1 212709 213248 D similar to ref|YP_059530.1| BioY [Streptococcus pyogenes MGAS10394]; BioY family protein 212709..213248 Streptococcus equi subsp. zooepidemicus MGCS10565 6760955 YP_002122584.1 CDS Sez_0193 NC_011134.1 213329 214129 D similar to ref|YP_059531.1| Metal-dependent hydrolase [Streptococcus pyogenes MGAS10394]; metal-dependent hydrolase 213329..214129 Streptococcus equi subsp. zooepidemicus MGCS10565 6760579 YP_002122585.1 CDS Sez_0194 NC_011134.1 214126 214620 D similar to ref|YP_001127758.1| deaminase [Streptococcus pyogenes str. Manfredo]; tRNA-specific adenosine-34 deaminase 214126..214620 Streptococcus equi subsp. zooepidemicus MGCS10565 6762144 YP_002122586.1 CDS Sez_0195 NC_011134.1 214730 215980 R similar to ref|YP_601669.1| S-layer protein / Peptidoglycan endo-beta-N-acetylglucosaminidase [Streptococcus pyogenes MGAS10750]; S-layer protein complement(214730..215980) Streptococcus equi subsp. zooepidemicus MGCS10565 6760578 YP_002122587.1 CDS Sez_0196 NC_011134.1 216089 217042 R similar to ref|ZP_00874436.1| Integrase, catalytic region [Streptococcus suis 89/1591]; transposase IS1239 complement(216089..217042) Streptococcus equi subsp. zooepidemicus MGCS10565 6762139 YP_002122588.1 CDS Sez_0197 NC_011134.1 217373 217969 D similar to emb|CAD33903.1| hypothethical protein [Streptococcus dysgalactiae subsp. equisimilis]; hypothetical protein 217373..217969 Streptococcus equi subsp. zooepidemicus MGCS10565 6760577 YP_002122589.1 CDS Sez_0198 NC_011134.1 218113 218238 R hypothetical protein complement(218113..218238) Streptococcus equi subsp. zooepidemicus MGCS10565 6762167 YP_002122590.1 CDS hasA NC_011134.1 218366 219619 D similar to gb|AAQ03572.1|AF414053_1 hyaluronan synthase [Streptococcus equi subsp. zooepidemicus]; Glycosaminoglycan synthesis. The hyaluronic acid capsule is involved in the pathogenicity of group A Streptococci; it may be the major virulence determinant.; hyaluronan synthase HasA 218366..219619 Streptococcus equi subsp. zooepidemicus MGCS10565 6760576 YP_002122591.1 CDS hasB NC_011134.1 219878 221083 D similar to gb|AAN65249.1|AF347022_2 UDP-glucose dehydrogenase [Streptococcus equi subsp. zooepidemicus]; Catalyzes the formation of UDP-glucuronic acid which is required for capsular hyaluronic acid synthesis.; UDP-glucose 6-dehydrogenase HasB 219878..221083 Streptococcus equi subsp. zooepidemicus MGCS10565 6762216 YP_002122592.1 CDS hasC.1 NC_011134.1 221133 222035 D similar to gb|AAN65250.1|AF347022_3 UDP-glucose pyrophosphorylase [Streptococcus equi subsp. zooepidemicus]; May play a role in stationary phase survival.; UTP-glucose-1-phosphate uridylyltransferase 221133..222035 Streptococcus equi subsp. zooepidemicus MGCS10565 6760575 YP_002122593.1 CDS glmU NC_011134.1 222202 223581 D similar to gb|AAQ05206.1|AF468690_1 UDP-N-acetyl-glucosamine pyrophosphorylase [Streptococcus equi subsp. zooepidemicus]; Bifunctional Enzyme Responsible For The Acetylation Of Glc-N-1-P To Give Glcnac-1-P And The Synthesis Of UDP-Glcnac.; bifunctional N-acetylglucosamine-1-phosphate uridyltransferase / glucosamine-1-phosphate N-acetyltransferase GlmU 222202..223581 Streptococcus equi subsp. zooepidemicus MGCS10565 6762135 YP_002122594.1 CDS pgi NC_011134.1 223758 225107 D functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis; catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate; member of PGI family; glucose-6-phosphate isomerase 223758..225107 Streptococcus equi subsp. zooepidemicus MGCS10565 6760574 YP_002122595.1 CDS sorD NC_011134.1 225693 226493 D Converts D-sorbitol-dphosphate to D-fructose-6-phosphate; sorbitol-6-phosphate 2-dehydrogenase 225693..226493 Streptococcus equi subsp. zooepidemicus MGCS10565 6762119 YP_002122596.1 CDS srlM NC_011134.1 226516 228384 D similar to ref|NP_720766.1| regulator of sorbitol operon [Streptococcus mutans UA159]; Positive regulator of sorbitol operon.; sorbitol operon transcription regulator SrlM 226516..228384 Streptococcus equi subsp. zooepidemicus MGCS10565 6760571 YP_002122597.1 CDS srlR NC_011134.1 228393 228845 D similar to ref|NP_720767.1| sorbitol operon activator [Streptococcus mutans UA159]; Positive regulator for sorbitol operon expression.; sorbitol operon activator SrlR 228393..228845 Streptococcus equi subsp. zooepidemicus MGCS10565 6762054 YP_002122598.1 CDS srlA NC_011134.1 228993 229538 D similar to ref|NP_720768.1| PTS system, sorbitol (glucitol) phosphotransferase enzyme IIC2 [Streptococcus mutans UA159]; The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. This system is involved in glucitol/sorbitol transport.; glucitol/sorbitol permease IIC component SrlA 228993..229538 Streptococcus equi subsp. zooepidemicus MGCS10565 6760570 YP_002122599.1 CDS srlE NC_011134.1 229551 230543 D similar to ref|NP_720769.1| PTS system, sorbitol phosphotransferase enzyme IIBC [Streptococcus mutans UA159]; The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. This system is involved in glucitol/sorbitol transport.; PTS system glucitol/sorbitol-specific transporter subunit IIBC 229551..230543 Streptococcus equi subsp. zooepidemicus MGCS10565 6762045 YP_002122600.1 CDS srlB NC_011134.1 230631 230942 D similar to ref|NP_720770.1| PTS system, sorbitol-specific enzyme IIA [Streptococcus mutans UA159]; The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. This system is involved in glucitol/sorbitol transport.; Glucitol/sorbitol-specific phosphotransferase enzyme IIA component SrlB 230631..230942 Streptococcus equi subsp. zooepidemicus MGCS10565 6760569 YP_002122601.1 CDS Sez_0210 NC_011134.1 231454 232884 D similar to ref|ZP_02184619.1| cassette chromosome recombinase B1 [Carnobacterium sp. AT7]; transposase IS663-like 231454..232884 Streptococcus equi subsp. zooepidemicus MGCS10565 6761995 YP_002122602.1 CDS Sez_0211 NC_011134.1 233037 234323 D similar to ref|ZP_00513513.1| abortive infection protein, [Crocosphaera watsonii WH8501]; abortive phage resistance protein 233037..234323 Streptococcus equi subsp. zooepidemicus MGCS10565 6760568 YP_002122603.1 CDS Sez_0212 NC_011134.1 234330 234965 D similar to ref|ZP_01628459.1| hypothetical protein N9414_15200 [Nodularia spumigena CCY9414]; abortive phage resistance protein 234330..234965 Streptococcus equi subsp. zooepidemicus MGCS10565 6761929 YP_002122604.1 CDS sclZ.5 NC_011134.1 235389 236399 R similar to gb|AAQ91579.1| collagen-like protein 3 [Streptococcus equi]; Possible adhesin, has a collagen-structural-motif domain composed of 61 Gly-Xaa-Yaa repeats.; hypothetical protein complement(235389..236399) Streptococcus equi subsp. zooepidemicus MGCS10565 6760567 YP_002122605.1 CDS Sez_0214 NC_011134.1 237046 237579 D similar to ref|YP_821136.1| 5-formyltetrahydrofolate cyclo-ligase [Streptococcus thermophilus LMD-9]; Catalysis of the reaction: ATP + 5-formyltetrahydrofolate = ADP + phosphate + 5,10-methenyltetrahydrofolate.; 5-formyltetrahydrofolate cyclo-ligase 237046..237579 Streptococcus equi subsp. zooepidemicus MGCS10565 6761868 YP_002122606.1 CDS Sez_0215 NC_011134.1 237576 238259 D similar to ref|YP_059541.1| integral membrane protein (Rhomboid family) [Streptococcus pyogenes MGAS10394]; hypothetical protein 237576..238259 Streptococcus equi subsp. zooepidemicus MGCS10565 6760566 YP_002122607.1 CDS hasC.2 NC_011134.1 238548 239516 R similar to gb|AAQ05209.1|AF468691_2 UDP-glucose pyrophosphorylase [Streptococcus equi subsp. zooepidemicus]; Catalysis of the reaction: UTP + alpha-D-glucose 1-phosphate = diphosphate + UDP-glucose.; UTP-glucose-1-phosphate uridylyltransferase complement(238548..239516) Streptococcus equi subsp. zooepidemicus MGCS10565 6761859 YP_002122608.1 CDS gpsA NC_011134.1 239482 240501 R catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate; NAD(P)H-dependent glycerol-3-phosphate dehydrogenase complement(239482..240501) Streptococcus equi subsp. zooepidemicus MGCS10565 6760565 YP_002122609.1 CDS Sez_0218 NC_011134.1 240580 240717 R hypothetical protein complement(240580..240717) Streptococcus equi subsp. zooepidemicus MGCS10565 6761823 YP_002122610.1 CDS Sez_0219 NC_011134.1 240711 241160 D similar to ref|YP_599803.1| Transcriptional regulator, MarR family [Streptococcus pyogenes MGAS2096]; MarR family transcriptional regulator 240711..241160 Streptococcus equi subsp. zooepidemicus MGCS10565 6760564 YP_002122611.1 CDS Sez_0220 NC_011134.1 241153 242862 D similar to ref|YP_001127771.1| ABC transporter ATP-binding membrane protein [Streptococcus pyogenes str. Manfredo]; multidrug resistance ABC transporter ATP-binding protein/permease 241153..242862 Streptococcus equi subsp. zooepidemicus MGCS10565 6761806 YP_002122612.1 CDS Sez_0221 NC_011134.1 242862 244658 D similar to ref|NP_268592.1| ABC transporter (ATP-binding protein) [Streptococcus pyogenes M1 GAS]; multidrug resistance ABC transporter ATP-binding protein/permease 242862..244658 Streptococcus equi subsp. zooepidemicus MGCS10565 6760563 YP_002122613.1 CDS Sez_0222 NC_011134.1 244820 245587 D similar to ref|NP_663969.1| hypothetical protein SpyM3_0165 [Streptococcus pyogenes MGAS315]; Possibly invovlved in DNA integration/recombination/invertion.; hypothetical protein 244820..245587 Streptococcus equi subsp. zooepidemicus MGCS10565 6761675 YP_002122614.1 CDS dut NC_011134.1 245767 246213 D catalyzes the formation of dUMP from dUTP; deoxyuridine 5'-triphosphate nucleotidohydrolase 245767..246213 Streptococcus equi subsp. zooepidemicus MGCS10565 6760562 YP_002122615.1 CDS radA NC_011134.1 246279 247640 D Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents; DNA repair protein RadA 246279..247640 Streptococcus equi subsp. zooepidemicus MGCS10565 6761723 YP_002122616.1 CDS Sez_0225 NC_011134.1 248407 248913 D similar to ref|YP_821127.1| Carbonic anhydrase [Streptococcus thermophilus LMD-9]; Carbonate hydro-lyase (carbon-dioxide-forming).; carbonic anhydrase 248407..248913 Streptococcus equi subsp. zooepidemicus MGCS10565 6760561 YP_002122617.1 CDS Sez_0226 NC_011134.1 249041 249754 D similar to ref|YP_279665.1| hypothetical protein M28_Spy0196 [Streptococcus pyogenes MGAS6180]; HTH DNA-binding protein 249041..249754 Streptococcus equi subsp. zooepidemicus MGCS10565 6761557 YP_002122618.1 CDS gltX NC_011134.1 250356 251801 D Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation; glutamyl-tRNA synthetase 250356..251801 Streptococcus equi subsp. zooepidemicus MGCS10565 6760560 YP_002122619.1 CDS fasB NC_011134.1 252244 253590 D similar to ref|YP_597813.1| Sensory transduction protein kinase FasB [Streptococcus pyogenes MGAS10270]; sensory transduction protein kinase FasB 252244..253590 Streptococcus equi subsp. zooepidemicus MGCS10565 6761607 YP_002122620.1 CDS fasC NC_011134.1 253602 254900 D similar to ref|YP_597814.1| Sensory transduction protein kinase FasC [Streptococcus pyogenes MGAS10270]; sensory transduction protein kinase FasC 253602..254900 Streptococcus equi subsp. zooepidemicus MGCS10565 6760558 YP_002122621.1 CDS fasA NC_011134.1 254904 255644 D similar to gb|AAL78045.1| response regulator FasA [Streptococcus dysgalactiae subsp. equisimilis]; response regulator FasA 254904..255644 Streptococcus equi subsp. zooepidemicus MGCS10565 6761560 YP_002122622.1 CDS Sez_0231 NC_011134.1 256477 256686 D hypothetical protein 256477..256686 Streptococcus equi subsp. zooepidemicus MGCS10565 6760557 YP_002122623.1 CDS Sez_0232 NC_011134.1 256836 257543 D similar to ref|NP_816714.1| ABC transporter, ATP-binding protein [Enterococcus faecalis V583]; Involved in transport.; ABC transporter ATP-binding protein 256836..257543 Streptococcus equi subsp. zooepidemicus MGCS10565 6761501 YP_002122624.1 CDS Sez_0233 NC_011134.1 257548 258897 D similar to ref|NP_816713.1| hypothetical protein EF3103 [Enterococcus faecalis V583]; hypothetical protein 257548..258897 Streptococcus equi subsp. zooepidemicus MGCS10565 6760556 YP_002122625.1 CDS Sez_0234 NC_011134.1 259174 259539 D similar to ref|NP_816711.1| hypothetical protein EF3101 [Enterococcus faecalis V583]; hypothetical protein 259174..259539 Streptococcus equi subsp. zooepidemicus MGCS10565 6761447 YP_002122626.1 CDS Sez_0235 NC_011134.1 259548 260039 D similar to ref|NP_816709.1| transporter accessory protein, [Enterococcus faecalis V583]; transporter accessory protein 259548..260039 Streptococcus equi subsp. zooepidemicus MGCS10565 6760555 YP_002122627.1 CDS rnpA NC_011134.1 260270 260629 D protein component of RNaseP which catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'terminus; this enzyme also cleaves other RNA substrates; ribonuclease P 260270..260629 Streptococcus equi subsp. zooepidemicus MGCS10565 6761373 YP_002122628.1 CDS oxaA1 NC_011134.1 260613 261422 D similar to ref|YP_001127782.1| membrane protein OxaA 1 precursor [Streptococcus pyogenes str. Manfredo]; Required for the insertion of integral membrane proteins into the membrane. May also be involved in protein secretion processes.; membrane protein OxaA 260613..261422 Streptococcus equi subsp. zooepidemicus MGCS10565 6760554 YP_002122629.1 CDS jag NC_011134.1 261434 262333 D similar to ref|YP_595942.1| jag protein [Streptococcus pyogenes MGAS9429]; RNA binding; Jag protein 261434..262333 Streptococcus equi subsp. zooepidemicus MGCS10565 6761441 YP_002122630.1 CDS Sez_0239 NC_011134.1 262455 262688 D similar to gb|EAY64209.1| conserved hypothetical protein [Burkholderia cenocepacia PC184]; hypothetical protein 262455..262688 Streptococcus equi subsp. zooepidemicus MGCS10565 6760553 YP_002122631.1 CDS Sez_0240 NC_011134.1 262860 263282 D similar to ref|ZP_00230000.1| hypothetical protein LMOh7858_0095 [Listeria monocytogenes str. 4b H7858]; hypothetical protein 262860..263282 Streptococcus equi subsp. zooepidemicus MGCS10565 6761418 YP_002122632.1 CDS nanE NC_011134.1 263812 264522 D Converts N-acetylmannosamine-6-phosphate to N-acetylglucosamine-6-phosphate; N-acetylmannosamine-6-phosphate 2-epimerase 263812..264522 Streptococcus equi subsp. zooepidemicus MGCS10565 6760552 YP_002122633.1 CDS ptsG NC_011134.1 264527 266038 D similar to ref|YP_001198767.1| Phosphotransferase system IIC component, glucose/maltose/N-acetylglucosamine-specific [Streptococcus suis 05ZYH33]; The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. This system is involved in glucose transport.; PTS system glucose-specific transporter subunit IICBA 264527..266038 Streptococcus equi subsp. zooepidemicus MGCS10565 6761392 YP_002122634.1 CDS ptsG NC_011134.1 266040 266555 D similar to ref|YP_603278.1| PTS system, glucose-specific IIABC component [Streptococcus pyogenes MGAS10750]; The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. This system is involved in glucose transport.; PTS system maltose and glucose-specific transporter subunit IIABC 266040..266555 Streptococcus equi subsp. zooepidemicus MGCS10565 6760551 YP_002122635.1 CDS rpmH NC_011134.1 266959 267093 D in Escherichia coli transcription of this gene is enhanced by polyamines; 50S ribosomal protein L34 266959..267093 Streptococcus equi subsp. zooepidemicus MGCS10565 6761386 YP_002122636.1 CDS nanE NC_011134.1 267380 268105 D Converts N-acetylmannosamine-6-phosphate to N-acetylglucosamine-6-phosphate; N-acetylmannosamine-6-phosphate 2-epimerase 267380..268105 Streptococcus equi subsp. zooepidemicus MGCS10565 6760550 YP_002122637.1 CDS Sez_0246 NC_011134.1 268124 269437 D similar to ref|YP_279676.1| N-acetylneuraminate-binding protein [Streptococcus pyogenes MGAS6180]; sugar ABC transporter substrate-binding protein 268124..269437 Streptococcus equi subsp. zooepidemicus MGCS10565 6761364 YP_002122638.1 CDS Sez_0247 NC_011134.1 269559 270425 D similar to ref|YP_597823.1| N-acetylneuraminate transport system permease [Streptococcus pyogenes MGAS10270]; Probably part of the binding-protein-dependent transport system yurMNO. Probably responsible for the translocation of the substrate across the membrane.; N-acetylneuraminate ABC transporter permease 269559..270425 Streptococcus equi subsp. zooepidemicus MGCS10565 6760549 YP_002122639.1 CDS Sez_0248 NC_011134.1 270438 271268 D similar to ref|NP_663987.1| sugar transport protein (permease) [Streptococcus pyogenes MGAS315]; Part of the binding-protein-dependent transport system for L-arabinose. Probably responsible for the translocation of the substrate across the membrane.; sugar ABC transporter permease 270438..271268 Streptococcus equi subsp. zooepidemicus MGCS10565 6760872 YP_002122640.1 CDS Sez_0249 NC_011134.1 271295 271750 D similar to ref|NP_606523.1| hypothetical protein spyM18_0238 [Streptococcus pyogenes MGAS8232]; hypothetical protein 271295..271750 Streptococcus equi subsp. zooepidemicus MGCS10565 6760548 YP_002122641.1 CDS Sez_0250 NC_011134.1 271775 272425 D similar to ref|YP_595949.1| hypothetical membrane spanning protein [Streptococcus pyogenes MGAS9429]; hypothetical protein 271775..272425 Streptococcus equi subsp. zooepidemicus MGCS10565 6760870 YP_002122642.1 CDS nanA NC_011134.1 272454 273374 D similar to ref|NP_268611.1| acylneuraminate lyase [Streptococcus pyogenes M1 GAS]; Catalyzes the cleavage of N-acetylneuraminic acid (sialic acid) to form pyruvate and N-acetylmannosamine via a Schiff base intermediate.; N-acetylneuraminate lyase 272454..273374 Streptococcus equi subsp. zooepidemicus MGCS10565 6760547 YP_002122643.1 CDS Sez_0252 NC_011134.1 273389 274273 D Catalysis of ATP + N-acyl-D-mannosamine = ADP + N-acyl-D-mannosamine 6-phosphate.; N-acetylmannosamine kinase 273389..274273 Streptococcus equi subsp. zooepidemicus MGCS10565 6760868 YP_002122644.1 CDS Sez_0253 NC_011134.1 274273 275241 D cephalosporin-C deacetylase; similar to ref|YP_328767.1| acetyl xylan esterase, [Streptococcus agalactiae A909]; acetyl xylan esterase 1 274273..275241 Streptococcus equi subsp. zooepidemicus MGCS10565 6760545 YP_002122645.1 CDS rpiR NC_011134.1 275390 276184 R similar to ref|YP_328768.1| phosphosugar-binding transcriptional regulator, RpiR family [Streptococcus agalactiae A909]; Binding to a specific DNA sequence in order to modulate transcription.; sialic acid utilization regulator, RpiR family complement(275390..276184) Streptococcus equi subsp. zooepidemicus MGCS10565 6760866 YP_002122646.1 CDS Sez_0255 NC_011134.1 276443 277216 D similar to ref|YP_001127793.1| TatD related DNase [Streptococcus pyogenes str. Manfredo]; deoxyribonuclease 276443..277216 Streptococcus equi subsp. zooepidemicus MGCS10565 6760544 YP_002122647.1 CDS Sez_0256 NC_011134.1 277188 277784 D similar to ref|YP_279684.1| ribonuclease M5 [Streptococcus pyogenes MGAS6180]; Interacting selectively with any nucleic acid.; ribonuclease M5 277188..277784 Streptococcus equi subsp. zooepidemicus MGCS10565 6760864 YP_002122648.1 CDS Sez_0257 NC_011134.1 277855 278529 R similar to ref|YP_001201713.1| Thiol-disulfide isomerase and thioredoxin [Streptococcus suis 98HAH33]; transport accessory protein complement(277855..278529) Streptococcus equi subsp. zooepidemicus MGCS10565 6760543 YP_002122649.1 CDS ksgA NC_011134.1 279168 280040 D catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin; dimethyladenosine transferase 279168..280040 Streptococcus equi subsp. zooepidemicus MGCS10565 6760862 YP_002122650.1 CDS engC NC_011134.1 280201 281073 D EngC; RsgA; CpgA; circularly permuted GTPase; ribosome small subunit-dependent GTPase A; has the pattern G4-G1-G3 as opposed to other GTPases; interacts strongly with 30S ribosome which stimulates GTPase activity; ribosome-associated GTPase 280201..281073 Streptococcus equi subsp. zooepidemicus MGCS10565 6760542 YP_002122651.1 CDS cbbE NC_011134.1 281082 281744 D catalyzes the interconversion of D-ribulose 5-phosphate to xylulose 5-phosphate; ribulose-phosphate 3-epimerase 281082..281744 Streptococcus equi subsp. zooepidemicus MGCS10565 6760857 YP_002122652.1 CDS thiN NC_011134.1 281737 282369 D similar to ref|YP_601714.1| Thiamin pyrophosphokinase [Streptococcus pyogenes MGAS10750]; Catalyzes the phosphorylation of thiamine to thiamine pyrophosphate.; thiamine pyrophosphokinase 281737..282369 Streptococcus equi subsp. zooepidemicus MGCS10565 6760541 YP_002122653.1 CDS rmuC NC_011134.1 282389 283642 D similar to ref|YP_601715.1| RmuC family protein [Streptococcus pyogenes MGAS10750]; Involved in DNA recombination.; DNA recombination protein RmuC-like 282389..283642 Streptococcus equi subsp. zooepidemicus MGCS10565 6760855 YP_002122654.1 CDS Sez_0263 NC_011134.1 283632 284570 D similar to ref|NP_268621.1| CMP-binding factor [Streptococcus pyogenes M1 GAS]; 3'-5' exoribonuclease; CMP-binding factor 283632..284570 Streptococcus equi subsp. zooepidemicus MGCS10565 6760540 YP_002122655.1 CDS purR NC_011134.1 284694 285485 D similar to ref|NP_268622.1| purine operon repressor [Streptococcus pyogenes M1 GAS]; Controls the transcription of the pur operon for purine biosynthetic genes.; pur operon repressor 284694..285485 Streptococcus equi subsp. zooepidemicus MGCS10565 6760853 YP_002122656.1 CDS Sez_0265 NC_011134.1 285522 288026 D similar to ref|NP_268623.1| surface exclusion protein [Streptococcus pyogenes M1 GAS]; surface exclusion protein 285522..288026 Streptococcus equi subsp. zooepidemicus MGCS10565 6760539 YP_002122657.1 CDS rpsL NC_011134.1 288208 288621 D interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance; 30S ribosomal protein S12 288208..288621 Streptococcus equi subsp. zooepidemicus MGCS10565 6760850 YP_002122658.1 CDS rpsG NC_011134.1 288642 289112 D binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit; 30S ribosomal protein S7 288642..289112 Streptococcus equi subsp. zooepidemicus MGCS10565 6760537 YP_002122659.1 CDS fus NC_011134.1 289441 291519 D EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene; elongation factor G 289441..291519 Streptococcus equi subsp. zooepidemicus MGCS10565 6760846 YP_002122660.1 CDS Sez_0269 NC_011134.1 291651 291821 R hypothetical protein complement(291651..291821) Streptococcus equi subsp. zooepidemicus MGCS10565 6760536 YP_002122661.1 CDS Sez_0270 NC_011134.1 291899 292909 D similar to dbj|BAD37145.1| glyceraldehyde-3-phosphate dehydrogenase [Streptococcus gordonii]; Also binds human plasminogen, Nephritis associated plasmin receptor, moonlighting dual function non-classical secreted protein.; NAD-dependent glyceraldehyde-3-phosphate dehydrogenase / plasmin(ogen) receptor 291899..292909 Streptococcus equi subsp. zooepidemicus MGCS10565 6760844 YP_002122662.1 CDS Sez_0271 NC_011134.1 293453 294307 D similar to emb|CAA73175.1| acid phosphatase [Streptococcus dysgalactiae subsp. equisimilis]; lipoprotein E 293453..294307 Streptococcus equi subsp. zooepidemicus MGCS10565 6760535 YP_002122663.1 CDS pgk NC_011134.1 294516 295712 D Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway; phosphoglycerate kinase 294516..295712 Streptococcus equi subsp. zooepidemicus MGCS10565 6760841 YP_002122664.1 CDS Sez_0273 NC_011134.1 295902 296030 D hypothetical protein 295902..296030 Streptococcus equi subsp. zooepidemicus MGCS10565 6760534 YP_002122665.1 CDS Sez_0274 NC_011134.1 296183 296317 R hypothetical protein complement(296183..296317) Streptococcus equi subsp. zooepidemicus MGCS10565 6760839 YP_002122666.1 CDS Sez_0275 NC_011134.1 296280 296657 D similar to ref|YP_597334.1| hypothetical protein MGAS9429_Spy1603 [Streptococcus pyogenes MGAS9429]; hypothetical protein 296280..296657 Streptococcus equi subsp. zooepidemicus MGCS10565 6760532 YP_002122667.1 CDS glnA NC_011134.1 297142 298488 D similar to ref|YP_597332.1| glutamine synthetase [Streptococcus pyogenes MGAS9429]; Plays an essential role in the metabolism of nitrogen by catalyzing the condensation of glutamate and ammonia to form glutamine, Class I enzymes (GSI) are specific to prokaryotes, and are oligomers of 12 identical subunits. The activity of GSI-type enzyme is controlled by the adenylation of a tyrosine residue. The adenylated enzyme is inactive.; glutamine synthetase 297142..298488 Streptococcus equi subsp. zooepidemicus MGCS10565 6760531 YP_002122668.1 CDS oppA NC_011134.1 298721 300379 D similar to ref|NP_687990.1| ABC transporter, substrate-binding protein [Streptococcus agalactiae 2603V/R]; This protein is a component of the oligopeptide permease, a binding protein-dependent transport system, It binds peptides up to five amino acids long with high affinity. Also required for sporulation and competence.; oligopeptide-binding protein OppA precursor 298721..300379 Streptococcus equi subsp. zooepidemicus MGCS10565 6760833 YP_002122669.1 CDS oppB NC_011134.1 300546 301460 D similar to ref|NP_687185.1| oligopeptide ABC transporter, permease [Streptococcus agalactiae 2603V/R]; Part of the binding-protein-dependent transport system for oligopeptides; probably responsible for the translocation of the substrate across the membrane. Also required for sporulation and competence.; oligopeptide transport system permease OppB 300546..301460 Streptococcus equi subsp. zooepidemicus MGCS10565 6760530 YP_002122670.1 CDS oppC NC_011134.1 301470 302501 D similar to ref|NP_687186.1| oligopeptide ABC transporter, permease [Streptococcus agalactiae 2603V/R]; Part of the binding-protein-dependent transport system for oligopeptides; probably responsible for the translocation of the substrate across the membrane. Also required for sporulation and competence.; oligopeptide transport system permease OppC 301470..302501 Streptococcus equi subsp. zooepidemicus MGCS10565 6760831 YP_002122671.1 CDS oppD NC_011134.1 302514 303560 D similar to ref|NP_687187.1| oligopeptide ABC transporter, ATP-binding protein [Streptococcus agalactiae 2603V/R]; Part of the binding protein-dependent transport system for oligopeptides. Probably responsible for energy coupling to the transport system. Required for sporulation and competence.; oligopeptide transport ATP-binding protein OppD 302514..303560 Streptococcus equi subsp. zooepidemicus MGCS10565 6760529 YP_002122672.1 CDS oppF NC_011134.1 303560 304495 D similar to ref|NP_687188.1| oligopeptide ABC transporter, ATP-binding protein [Streptococcus agalactiae 2603V/R]; Part of the binding-protein-dependent transport system for oligopeptides. Probably responsible for energy coupling to the transport system.; oligopeptide transport ATP-binding protein OppF 303560..304495 Streptococcus equi subsp. zooepidemicus MGCS10565 6760829 YP_002122673.1 CDS ykqC NC_011134.1 305117 306799 R similar to ref|ZP_00366343.1| COG0595: Predicted hydrolase of the metallo-beta-lactamase superfamily [Streptococcus pyogenes M49 591]; metallo-beta-lactamase family protein, Zn-dependent hydrolase complement(305117..306799) Streptococcus equi subsp. zooepidemicus MGCS10565 6760528 YP_002122674.1 CDS Sez_0285 NC_011134.1 306801 307031 R similar to ref|YP_603146.1| transcriptional regulator [Streptococcus pyogenes MGAS10750]; hypothetical protein complement(306801..307031) Streptococcus equi subsp. zooepidemicus MGCS10565 6760827 YP_002122675.1 CDS Sez_0286 NC_011134.1 307317 308015 D similar to ref|YP_603145.1| Non-proteolytic protein, peptidase family M22 [Streptococcus pyogenes MGAS10750]; molecular chaperone metal-dependent protease-like 307317..308015 Streptococcus equi subsp. zooepidemicus MGCS10565 6760527 YP_002122676.1 CDS rimI NC_011134.1 308018 308443 D similar to ref|YP_597328.1| ribosomal-protein-S18-alanine acetyltransferase [Streptococcus pyogenes MGAS9429]; This Enzyme Acetylates The N-Terminal Alanine Of Ribosomal Protein S18.; ribosomal-protein-alanine acetyltransferase 308018..308443 Streptococcus equi subsp. zooepidemicus MGCS10565 6760824 YP_002122677.1 CDS Sez_0288 NC_011134.1 308433 309449 D in most organisms, only the N-terminal domain is present in a single polypeptide; in some archaea this domain is fused to a kinase domain; this gene is essential for growth in Escherichia coli and Bacillus subtilis; the secreted glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins; the Pyrococcus structure shows DNA-binding properties, iron-binding, ATP-binding, and AP endonuclease activity; DNA-binding/iron metalloprotein/AP endonuclease 308433..309449 Streptococcus equi subsp. zooepidemicus MGCS10565 6760526 YP_002122678.1 CDS Sez_0289 NC_011134.1 309471 310499 D similar to ref|ZP_00875785.1| Protein of unknown function DUF218 [Streptococcus suis 89/1591]; hypothetical protein 309471..310499 Streptococcus equi subsp. zooepidemicus MGCS10565 6760821 YP_002122679.1 CDS rpsN2 NC_011134.1 310897 311232 R similar to ref|ZP_00366338.1| COG0199: Ribosomal protein S14 [Streptococcus pyogenes M49 591]; Known to be required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.; 30S ribosomal protein S14 complement(310897..311232) Streptococcus equi subsp. zooepidemicus MGCS10565 6760525 YP_002122680.1 CDS Sez_0291 NC_011134.1 311360 312532 R similar to ref|YP_281042.1| NAD(FAD)-utilizing dehydrogenase [Streptococcus pyogenes MGAS6180]; NAD(FAD)-utilizing dehydrogenase complement(311360..312532) Streptococcus equi subsp. zooepidemicus MGCS10565 6760818 YP_002122681.1 CDS Sez_0292 NC_011134.1 312658 313188 D similar to ref|YP_001127858.1| DNA-binding protein [Streptococcus pyogenes str. Manfredo]; hypothetical protein 312658..313188 Streptococcus equi subsp. zooepidemicus MGCS10565 6760524 YP_002122682.1 CDS polC NC_011134.1 313233 313820 D 3'-5' exonuclease of DNA polymerase III; DNA polymerase III subunit epsilon 313233..313820 Streptococcus equi subsp. zooepidemicus MGCS10565 6760814 YP_002122683.1 CDS Sez_0294 NC_011134.1 313915 314646 D similar to ref|YP_599257.1| MerR family transcriptional regulator [Streptococcus pyogenes MGAS10270]; Transcriptional regulator.; MerR family transcriptional regulator 313915..314646 Streptococcus equi subsp. zooepidemicus MGCS10565 6760522 YP_002122684.1 CDS Sez_0295 NC_011134.1 314722 315237 D similar to ref|YP_602677.1| Transposase [Streptococcus pyogenes MGAS10750]; transposase IS861 orfA 314722..315237 Streptococcus equi subsp. zooepidemicus MGCS10565 6760812 YP_002122685.1 CDS Sez_0296 NC_011134.1 315261 316064 D similar to ref|YP_596865.1| transposase [Streptococcus pyogenes MGAS9429]; transposase IS861 orfB 315261..316064 Streptococcus equi subsp. zooepidemicus MGCS10565 6760521 YP_002122686.1 CDS Sez_0297 NC_011134.1 316121 316420 R similar to ref|YP_281033.1| hypothetical protein M28_Spy1568 [Streptococcus pyogenes MGAS6180]; hypothetical protein complement(316121..316420) Streptococcus equi subsp. zooepidemicus MGCS10565 6760810 YP_002122687.1 CDS intR NC_011134.1 316498 317649 R similar to ref|NP_816189.1| site-specific recombinase, phage integrase family [Enterococcus faecalis V583]; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The xerC-xerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.; tyrosine recombinase XerC complement(316498..317649) Streptococcus equi subsp. zooepidemicus MGCS10565 6760520 YP_002122688.1 CDS Sez_0299 NC_011134.1 317636 317923 R similar to ref|NP_813967.1| hypothetical protein EF0165 [Enterococcus faecalis V583]; hypothetical protein complement(317636..317923) Streptococcus equi subsp. zooepidemicus MGCS10565 6760806 YP_002122689.1 CDS Sez_0300 NC_011134.1 317975 319210 R similar to ref|NP_965557.1| hypothetical protein LJ1751 [Lactobacillus johnsonii NCC 533]; Unknown, has some similarity with plasmid/phage replication initiation proteins may function with Sez_0298 which has similarity with plasmid/phage integrase/recombinase.; hypothetical protein complement(317975..319210) Streptococcus equi subsp. zooepidemicus MGCS10565 6760519 YP_002122690.1 CDS Sez_0301 NC_011134.1 319372 319665 R similar to ref|ZP_01817519.1| hypothetical protein CGSSp3BS71_03347 [Streptococcus pneumoniae SP3-BS71]; hypothetical protein complement(319372..319665) Streptococcus equi subsp. zooepidemicus MGCS10565 6760803 YP_002122691.1 CDS Sez_0302 NC_011134.1 320151 320594 R similar to ref|XP_788744.2| PREDICTED: similar to kelch-like ECH-associated protein 1 [Strongylocentrotus purpuratus]; hypothetical protein complement(320151..320594) Streptococcus equi subsp. zooepidemicus MGCS10565 6760518 YP_002122692.1 CDS Sez_0303 NC_011134.1 320885 322174 D similar to ref|ZP_01968479.1| hypothetical protein RUMTOR_02056 [Ruminococcus torques ATCC 27756]; hypothetical protein 320885..322174 Streptococcus equi subsp. zooepidemicus MGCS10565 6760801 YP_002122693.1 CDS Sez_0304 NC_011134.1 322293 323123 R similar to ref|XP_001431093.1| hypothetical protein GSPATT00033548001 [Paramecium tetraurelia strain d4-2]; hypothetical protein complement(322293..323123) Streptococcus equi subsp. zooepidemicus MGCS10565 6760517 YP_002122694.1 CDS Sez_0305 NC_011134.1 323629 323766 D similar to ref|YP_536282.1| hypothetical protein LSL_1395 [Lactobacillus salivarius UCC118]; hypothetical protein 323629..323766 Streptococcus equi subsp. zooepidemicus MGCS10565 6760799 YP_002122695.1 CDS Sez_0306 NC_011134.1 323797 324507 D similar to ref|XP_001592791.1| hypothetical protein SS1G_05712 [Sclerotinia sclerotiorum 1980]; hypothetical protein 323797..324507 Streptococcus equi subsp. zooepidemicus MGCS10565 6760516 YP_002122696.1 CDS Sez_0307 NC_011134.1 324534 325703 D similar to ref|ZP_00875721.1| Helix-turn-helix motif:Protein of unknown function DUF955 [Streptococcus suis 89/1591]; transcriptional regulator 324534..325703 Streptococcus equi subsp. zooepidemicus MGCS10565 6760797 YP_002122697.1 CDS Sez_0308 NC_011134.1 325743 326762 D similar to ref|YP_001308760.1| hypothetical protein Cbei_1630 [Clostridium beijerinckii NCIMB 8052]; hypothetical protein 325743..326762 Streptococcus equi subsp. zooepidemicus MGCS10565 6760515 YP_002122698.1 CDS Sez_0309 NC_011134.1 327184 327321 D hypothetical protein 327184..327321 Streptococcus equi subsp. zooepidemicus MGCS10565 6760795 YP_002122699.1 CDS Sez_0310 NC_011134.1 327391 327834 D similar to ref|YP_330353.1| hypothetical protein SAK_1753 [Streptococcus agalactiae A909]; hypothetical protein 327391..327834 Streptococcus equi subsp. zooepidemicus MGCS10565 6760514 YP_002122700.1 CDS Sez_0311 NC_011134.1 327973 328659 D similar to ref|NP_734897.1| similar to two-component response regulator [Streptococcus agalactiae NEM316]; Member of the two-component regulatory system, has some similarity with SaeR and PhoP.; DNA-binding response regulator 327973..328659 Streptococcus equi subsp. zooepidemicus MGCS10565 6760793 YP_002122701.1 CDS Sez_0312 NC_011134.1 328697 329707 D similar to ref|NP_687428.1| sensor histidine kinase [Streptococcus agalactiae 2603V/R]; Member of the two-component regulatory system, has similarity with SaeS and PhoR.; two component system histidine kinase 328697..329707 Streptococcus equi subsp. zooepidemicus MGCS10565 6760513 YP_002122702.1 CDS fnz NC_011134.1 330079 331809 R similar to dbj|BAD00710.1| fibronectin-binding protein [Streptococcus equi subsp. zooepidemicus]; Unknown, cell surface fibronectin-binding protein.; fibronectin-binding protein Fnz complement(330079..331809) Streptococcus equi subsp. zooepidemicus MGCS10565 6760790 YP_002122703.1 CDS Sez_0314 NC_011134.1 332050 333558 D similar to ref|NP_268584.1| regulatory protein - RofA related [Streptococcus pyogenes M1 GAS]; RofA-like, regulator of adjacent predicted cell surface fibronectin-binding protein.; transcriptional regulator, RofA-like protein (RALP) 332050..333558 Streptococcus equi subsp. zooepidemicus MGCS10565 6760511 YP_002122704.1 CDS Sez_0315 NC_011134.1 334154 334936 D similar to ref|YP_001643140.1| Abortive infection protein [Bacillus weihenstephanensis KBAB4]; CAAX amino terminal protease family protein 334154..334936 Streptococcus equi subsp. zooepidemicus MGCS10565 6760788 YP_002122705.1 CDS Sez_0316 NC_011134.1 335194 335508 R similar to ref|NP_269854.1| repressor - phage associated [Streptococcus pyogenes M1 GAS]; repressor complement(335194..335508) Streptococcus equi subsp. zooepidemicus MGCS10565 6760510 YP_002122706.1 CDS Sez_0317 NC_011134.1 335726 335968 D similar to ref|YP_060907.1| Transcriptional regulator, Cro/CI family [Streptococcus pyogenes MGAS10394]; Cro/CI family transcriptional regulator 335726..335968 Streptococcus equi subsp. zooepidemicus MGCS10565 6760786 YP_002122707.1 CDS Sez_0318 NC_011134.1 336157 336549 D similar to ref|YP_329140.1| pyridoxamine 5'-phosphate oxidase family [Streptococcus agalactiae A909]; hypothetical protein 336157..336549 Streptococcus equi subsp. zooepidemicus MGCS10565 6760509 YP_002122708.1 CDS pepX NC_011134.1 336655 338940 R catalyzes the removal of N-terminal dipeptides when proline is the penultimate residue; x-prolyl-dipeptidyl aminopeptidase complement(336655..338940) Streptococcus equi subsp. zooepidemicus MGCS10565 6760783 YP_002122709.1 CDS Sez_0320 NC_011134.1 338960 339619 R similar to ref|NP_269852.1| transcriptional regulatory protein [Streptococcus pyogenes M1 GAS]; Crp/Fnr family transcriptional regulator complement(338960..339619) Streptococcus equi subsp. zooepidemicus MGCS10565 6760508 YP_002122710.1 CDS norA NC_011134.1 339788 340987 D similar to ref|YP_281028.1| quinolone resistance norA protein [Streptococcus pyogenes MGAS6180]; quinolone antibiotic resistance protein.; major facilitator superfamily transporter 339788..340987 Streptococcus equi subsp. zooepidemicus MGCS10565 6760781 YP_002122711.1 CDS Sez_0322 NC_011134.1 341007 341459 D similar to ref|NP_688723.1| universal stress protein family [Streptococcus agalactiae 2603V/R]; universal stress protein family 341007..341459 Streptococcus equi subsp. zooepidemicus MGCS10565 6760507 YP_002122712.1 CDS gla NC_011134.1 341579 342409 D similar to ref|YP_601194.1| Aquaporin / Glycerol uptake facilitator protein [Streptococcus pyogenes MGAS2096]; Mixed channel protein that transports both water and glycerol.; glycerol facilitator-aquaporin Gla 341579..342409 Streptococcus equi subsp. zooepidemicus MGCS10565 6760777 YP_002122713.1 CDS Sez_0324 NC_011134.1 342901 343656 D similar to ref|NP_269848.1| C3-degrading proteinase [Streptococcus pyogenes M1 GAS]; C3-degrading proteinase 342901..343656 Streptococcus equi subsp. zooepidemicus MGCS10565 6760506 YP_002122714.1 CDS Sez_0325 NC_011134.1 343653 344603 D similar to gb|AAT87717.1| Penicillin-binding protein [Streptococcus pyogenes MGAS10394]; Unknown, similar to beta lactamase.; esterase 343653..344603 Streptococcus equi subsp. zooepidemicus MGCS10565 6760775 YP_002122715.1 CDS pfl NC_011134.1 344824 347211 R similar to ref|NP_358009.1| Pyruvate formate-lyase [Streptococcus pneumoniae R6]; Glucose metabolism (nonoxidative conversion).; pyruvate formate-lyase complement(344824..347211) Streptococcus equi subsp. zooepidemicus MGCS10565 6760505 YP_002122716.1 CDS dinB NC_011134.1 347357 348460 D involved in translesion DNA polymerization with beta clamp of polymerase III; belongs to Y family of polymerases; does not contain proofreading function; DNA polymerase IV 347357..348460 Streptococcus equi subsp. zooepidemicus MGCS10565 6760773 YP_002122717.1 CDS Sez_0328 NC_011134.1 348603 349088 R similar to ref|NP_665398.1| hypothetical protein SpyM3_1594 [Streptococcus pyogenes MGAS315]; hypothetical protein complement(348603..349088) Streptococcus equi subsp. zooepidemicus MGCS10565 6760504 YP_002122718.1 CDS recD NC_011134.1 349184 351688 R similar to ref|YP_603119.1| Exodeoxyribonuclease V alpha chain [Streptococcus pyogenes MGAS10750]; Exhibits several catalytic activities, including ATP-dependent exonuclease, ATP-stimulated endonuclease, ATP-dependent unwinding and DNA-dependent ATPase activities. strand cleavage occurs 5' to 3' during the unwinding of duplex DNA at Chi sequences, which locally stimulate recombination.; exodeoxyribonuclease V subunit alpha complement(349184..351688) Streptococcus equi subsp. zooepidemicus MGCS10565 6760771 YP_002122719.1 CDS lepB NC_011134.1 351812 352411 R similar to ref|YP_603118.1| Signal peptidase I [Streptococcus pyogenes MGAS10750]; signal peptidase I complement(351812..352411) Streptococcus equi subsp. zooepidemicus MGCS10565 6760503 YP_002122720.1 CDS rnhC NC_011134.1 352436 353311 R An endonuclease that specifically degrades the RNA strand of RNA-DNA hybrids; ribonuclease HIII complement(352436..353311) Streptococcus equi subsp. zooepidemicus MGCS10565 6760769 YP_002122721.1 CDS Sez_0332 NC_011134.1 353462 353773 D similar to ref|YP_597299.1| hypothetical cytosolic protein [Streptococcus pyogenes MGAS9429]; hypothetical protein 353462..353773 Streptococcus equi subsp. zooepidemicus MGCS10565 6760502 YP_002122722.1 CDS cvpA NC_011134.1 353770 354318 D similar to ref|YP_597298.1| CvpA family membrane protein [Streptococcus pyogenes MGAS9429]; colicin V production protein CvpA 353770..354318 Streptococcus equi subsp. zooepidemicus MGCS10565 6760767 YP_002122723.1 CDS mutSB NC_011134.1 354391 356727 D similar to ref|YP_140176.1| DNA mismatch repair protein [Streptococcus thermophilus LMG 18311]; recombination inhibitory protein MutS2 354391..356727 Streptococcus equi subsp. zooepidemicus MGCS10565 6760501 YP_002122724.1 CDS Sez_0335 NC_011134.1 356864 357073 D hypothetical protein 356864..357073 Streptococcus equi subsp. zooepidemicus MGCS10565 6760765 YP_002122725.1 CDS ykgC NC_011134.1 357070 358422 R Involved in disulfide oxidoreductase activity and electron transport; pyridine nucleotide-disulfide oxidoreductase complement(357070..358422) Streptococcus equi subsp. zooepidemicus MGCS10565 6760500 YP_002122726.1 CDS trxA NC_011134.1 358568 358882 D similar to ref|NP_722180.1| thioredoxin [Streptococcus mutans UA159]; Component of the thioredoxin-thioredoxin reductase system. Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions.; thioredoxin 358568..358882 Streptococcus equi subsp. zooepidemicus MGCS10565 6760763 YP_002122727.1 CDS mlpZ NC_011134.1 359128 360108 R similar to gb|AAQ08496.1| Szp protein [Streptococcus equi subsp. zooepidemicus]; This protein is one of the different antigenic serotypes of protein M. Protein M is closely associated with virulence of the bacterium and can render the organism resistant to phagocytosis.; M-like protein complement(359128..360108) Streptococcus equi subsp. zooepidemicus MGCS10565 6760499 YP_002122728.1 CDS mutY NC_011134.1 360903 362051 R similar to ref|YP_140171.1| A/G-specific adenine glycosylase [Streptococcus thermophilus LMG 18311]; Adenine glycosylase active on G-A and C-A mispairs.; A/G-specific adenine glycosylase complement(360903..362051) Streptococcus equi subsp. zooepidemicus MGCS10565 6760761 YP_002122729.1 CDS Sez_0340 NC_011134.1 362177 362365 D similar to ref|NP_721760.1| hypothetical protein SMU.1400c [Streptococcus mutans UA159]; hypothetical protein 362177..362365 Streptococcus equi subsp. zooepidemicus MGCS10565 6760498 YP_002122730.1 CDS Sez_0341 NC_011134.1 363170 363310 D hypothetical protein 363170..363310 Streptococcus equi subsp. zooepidemicus MGCS10565 6760759 YP_002122731.1 CDS rpsF NC_011134.1 363429 363719 D binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21; 30S ribosomal protein S6 363429..363719 Streptococcus equi subsp. zooepidemicus MGCS10565 6760497 YP_002122732.1 CDS ssb2 NC_011134.1 363738 364226 D binds to single stranded DNA and may facilitate the binding and interaction of other proteins to DNA; single-stranded DNA-binding protein 363738..364226 Streptococcus equi subsp. zooepidemicus MGCS10565 6760756 YP_002122733.1 CDS rpsR NC_011134.1 364385 364624 D binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit; 30S ribosomal protein S18 364385..364624 Streptococcus equi subsp. zooepidemicus MGCS10565 6760496 YP_002122734.1 CDS Sez_0345 NC_011134.1 364825 365340 D similar to ref|YP_602677.1| Transposase [Streptococcus pyogenes MGAS10750]; transposase IS861 orfA 364825..365340 Streptococcus equi subsp. zooepidemicus MGCS10565 6760754 YP_002122735.1 CDS Sez_0346 NC_011134.1 365364 366167 D similar to ref|YP_596865.1| transposase [Streptococcus pyogenes MGAS9429]; transposase IS861 orfB 365364..366167 Streptococcus equi subsp. zooepidemicus MGCS10565 6760495 YP_002122736.1 CDS Sez_0347 NC_011134.1 366317 366967 R similar to ref|YP_281004.1| hypothetical membrane spanning protein [Streptococcus pyogenes MGAS6180]; hypothetical protein complement(366317..366967) Streptococcus equi subsp. zooepidemicus MGCS10565 6760752 YP_002122737.1 CDS corA NC_011134.1 367144 368088 R similar to ref|YP_001127890.1| CorA-like Mg2+ transporter protein [Streptococcus pyogenes str. Manfredo]; May play a role in the transport of magnesium.; magnesium and cobalt transport protein CorA complement(367144..368088) Streptococcus equi subsp. zooepidemicus MGCS10565 6760493 YP_002122738.1 CDS uvrA NC_011134.1 368284 371106 D The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate; excinuclease ABC subunit A 368284..371106 Streptococcus equi subsp. zooepidemicus MGCS10565 6760750 YP_002122739.1 CDS Sez_0350 NC_011134.1 371684 372781 D similar to ref|YP_060856.1| Xaa-Pro dipeptidase [Streptococcus pyogenes MGAS10394]; The hydrolysis of a peptide bond or bonds within a protein.; aminopeptidase 371684..372781 Streptococcus equi subsp. zooepidemicus MGCS10565 6760492 YP_002122740.1 CDS comEB NC_011134.1 372824 373285 D similar to ref|YP_060855.1| ComE operon protein 2 [Streptococcus pyogenes MGAS10394]; Catalysis of the reaction: dCMP + H2O = dUMP + NH3, Dispensable for transformability.; dCMP deaminase; late competence protein ComEB 372824..373285 Streptococcus equi subsp. zooepidemicus MGCS10565 6760748 YP_002122741.1 CDS efp NC_011134.1 373379 373936 D Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA; elongation factor P 373379..373936 Streptococcus equi subsp. zooepidemicus MGCS10565 6760491 YP_002122742.1 CDS Sez_0353 NC_011134.1 373979 374368 D similar to ref|YP_001127895.1| hypothetical protein SpyM50304 [Streptococcus pyogenes str. Manfredo]; general stress protein 373979..374368 Streptococcus equi subsp. zooepidemicus MGCS10565 6760746 YP_002122743.1 CDS nusB NC_011134.1 374394 374813 D Regulates rRNA biosynthesis by transcriptional antitermination; transcription antitermination protein NusB 374394..374813 Streptococcus equi subsp. zooepidemicus MGCS10565 6760490 YP_002122744.1 CDS Sez_0355 NC_011134.1 375046 375312 D similar to ref|YP_001451052.1| hypothetical protein SGO_1783 [Streptococcus gordonii str. Challis substr. CH1]; hypothetical protein 375046..375312 Streptococcus equi subsp. zooepidemicus MGCS10565 6760744 YP_002122745.1 CDS Sez_0356 NC_011134.1 375324 375683 D similar to ref|YP_001035341.1| hypothetical protein SSA_1393 [Streptococcus sanguinis SK36]; hypothetical protein 375324..375683 Streptococcus equi subsp. zooepidemicus MGCS10565 6760489 YP_002122746.1 CDS Sez_0357 NC_011134.1 375674 376573 D similar to ref|YP_001035340.1| hypothetical protein SSA_1392 [Streptococcus sanguinis SK36]; hypothetical protein 375674..376573 Streptococcus equi subsp. zooepidemicus MGCS10565 6760742 YP_002122747.1 CDS Sez_0358 NC_011134.1 376570 377013 D similar to ref|YP_697958.1| bacteriocin [Clostridium perfringens SM101]; hypothetical protein 376570..377013 Streptococcus equi subsp. zooepidemicus MGCS10565 6760488 YP_002122748.1 CDS Sez_0359 NC_011134.1 377271 377516 D similar to ref|YP_001035338.1| hypothetical protein SSA_1390 [Streptococcus sanguinis SK36]; hypothetical protein 377271..377516 Streptococcus equi subsp. zooepidemicus MGCS10565 6760740 YP_002122749.1 CDS Sez_0360 NC_011134.1 377723 377929 D similar to ref|XP_503073.1| hypothetical protein [Yarrowia lipolytica]; hypothetical protein 377723..377929 Streptococcus equi subsp. zooepidemicus MGCS10565 6760487 YP_002122750.1 CDS scrR NC_011134.1 377894 378859 R similar to ref|YP_282907.1| sucrose operon repressor [Streptococcus pyogenes MGAS5005]; Negative regulator of scrB expression.; LacI family transcriptional regulator complement(377894..378859) Streptococcus equi subsp. zooepidemicus MGCS10565 6760738 YP_002122751.1 CDS scrB NC_011134.1 378864 380303 R similar to ref|YP_280995.1| sucrose-6-phosphate hydrolase [Streptococcus pyogenes MGAS6180]; Catalysis of the hydrolysis of terminal non-reducing beta-D-fructofuranoside residues in beta-D-fructofuranosides.; sucrose-6-phosphate hydrolase complement(378864..380303) Streptococcus equi subsp. zooepidemicus MGCS10565 6760485 YP_002122752.1 CDS scrA NC_011134.1 380582 382465 D similar to ref|YP_001127899.1| Gene info PTS system, sucrose-specific IIABC component [Streptococcus pyogenes str. Manfredo]; The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. This system is involved in sucrose transport.; PTS system sucrose-specific transporter subunit IIABC 380582..382465 Streptococcus equi subsp. zooepidemicus MGCS10565 6760736 YP_002122753.1 CDS endOF2 NC_011134.1 382695 385730 D similar to ref|NP_665373.1| sucrose-specific PTS permease, enzyme II [Streptococcus pyogenes MGAS315]; Endohydrolysis of the di-N-acetylchitobiosyl unit in high-mannose glycopeptides and glycoproteins. Complex biantennary glycans are the preferred substrates. Tri- and tetraantennary glycans are not hydrolyzed, and high mannose glycans are very poor substrates.; endo-beta-N-acetylglucosaminidase F2 382695..385730 Streptococcus equi subsp. zooepidemicus MGCS10565 6760484 YP_002122754.1 CDS scrK NC_011134.1 386100 386984 D similar to ref|NP_607886.1| secreted endoglycosidase [Streptococcus pyogenes MGAS8232]; Catalysis of the reaction: ATP + D-fructose = ADP + D-fructose 6-phosphate.; fructokinase ScrK 386100..386984 Streptococcus equi subsp. zooepidemicus MGCS10565 6760733 YP_002122755.1 CDS pmi NC_011134.1 387130 388044 D similar to ref|NP_269816.1| mannose-6-phosphate isomerase [Streptococcus pyogenes M1 GAS]; Involved in the conversion of glucose to GDP-L-fucose.; mannose-6-phosphate isomerase 387130..388044 Streptococcus equi subsp. zooepidemicus MGCS10565 6760483 YP_002122756.1 CDS secA NC_011134.1 388422 390950 D functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond SecA1; SecA2 is not essential and seems to play a role in secretion of a subset of proteins; preprotein translocase subunit SecA 388422..390950 Streptococcus equi subsp. zooepidemicus MGCS10565 6760731 YP_002122757.1 CDS acpS NC_011134.1 391066 391422 D Catalyzes the formation of holo-ACP, which mediates the essential transfer of acyl fatty acid intermediates during the biosynthesis of fatty acids and lipids; 4'-phosphopantetheinyl transferase 391066..391422 Streptococcus equi subsp. zooepidemicus MGCS10565 6760482 YP_002122758.1 CDS alr NC_011134.1 391419 392519 D converts L-alanine to D-alanine which is used in cell wall biosynthesis; binds one pyridoxal phosphate per monomer; forms a homodimer; alanine racemase 391419..392519 Streptococcus equi subsp. zooepidemicus MGCS10565 6760729 YP_002122759.1 CDS ispZ NC_011134.1 392789 394204 D similar to ref|YP_599208.1| Immunogenic secreted protein [Streptococcus pyogenes MGAS10270]; pfam05257, CHAP domain. This domain corresponds to an amidase function, MurNAc-L-Ala amidase. Many of these proteins are involved in cell wall metabolism of bacteria. This domain is found at the N-terminus of the bifunctional Escherichia coli GSP synthetase/GSP amidase, where is functions as a glutathionylspermidine amidase.; hypothetical protein 392789..394204 Streptococcus equi subsp. zooepidemicus MGCS10565 6760481 YP_002122760.1 CDS Sez_0371 NC_011134.1 394405 398160 D similar to ref|YP_597265.1| Fe3+-siderophore transport protein [Streptococcus pyogenes MGAS9429]; Involoved in iron acquisition.; Fe3+-siderophore transport protein 394405..398160 Streptococcus equi subsp. zooepidemicus MGCS10565 6760727 YP_002122761.1 CDS Sez_0372 NC_011134.1 398413 399294 D similar to gb|ABI79311.1| heme-binding protein [Streptococcus equi subsp. equi]; heme-binding protein 398413..399294 Streptococcus equi subsp. zooepidemicus MGCS10565 6760480 YP_002122762.1 CDS Sez_0373 NC_011134.1 399278 400162 D similar to gb|ABI79312.1| heme-binding lipoprotein [Streptococcus equi subsp. equi]; Binds citrate-dependent iron(III); part of the binding- protein-dependent transport system for uptake of citrate-dependent iron(III).; ferrichrome ABC transporter substrate-binding lipoprotein 399278..400162 Streptococcus equi subsp. zooepidemicus MGCS10565 6760725 YP_002122763.1 CDS Sez_0374 NC_011134.1 400164 401186 D similar to ref|NP_665363.1| ferrichrome ABC transporter (permease) [Streptococcus pyogenes MGAS315]; This is one of the proteins involved in the high- affinity transport of ferrichrome.; heme ABC transporter permease 400164..401186 Streptococcus equi subsp. zooepidemicus MGCS10565 6760479 YP_002122764.1 CDS Sez_0375 NC_011134.1 401183 401965 D similar to ref|YP_060837.1| Ferrichrome transport ATP-binding protein [Streptococcus pyogenes MGAS10394]; Part of the binding-protein-dependent transport system for Fe(3+)-ferrichrome. Probably responsible for energy coupling to the transport system.; heme ABC transporter ATP-binding protein 401183..401965 Streptococcus equi subsp. zooepidemicus MGCS10565 6760722 YP_002122765.1 CDS Sez_0376 NC_011134.1 402011 403774 D similar to ref|NP_607874.1| ABC transporter (ATP-binding protein) [Streptococcus pyogenes MGAS8232]; Component of a transport system.; ABC transporter ATP-binding protein 402011..403774 Streptococcus equi subsp. zooepidemicus MGCS10565 6760478 YP_002122766.1 CDS Sez_0377 NC_011134.1 403767 405449 D similar to ref|YP_597258.1| ABC transporter ATP-binding protein [Streptococcus pyogenes MGAS9429]; Component of a transport system.; ABC transporter ATP-binding protein 403767..405449 Streptococcus equi subsp. zooepidemicus MGCS10565 6760720 YP_002122767.1 CDS Sez_0378 NC_011134.1 405430 406023 D similar to ref|NP_607872.1| hypothetical protein spyM18_1861 [Streptococcus pyogenes MGAS8232]; Permease component of an ABC transporter.; ABC transporter permease 405430..406023 Streptococcus equi subsp. zooepidemicus MGCS10565 6760477 YP_002122768.1 CDS Sez_0379 NC_011134.1 406020 406703 D similar to ref|NP_607871.1| hypothetical protein spyM18_1860 [Streptococcus pyogenes MGAS8232]; Possibly involved in cobalt transport.; transporter 406020..406703 Streptococcus equi subsp. zooepidemicus MGCS10565 6760717 YP_002122769.1 CDS Sez_0380 NC_011134.1 406700 408094 D similar to ref|YP_001127916.1| ABC transporter ATP-binding protein [Streptococcus pyogenes str. Manfredo]; Part of the ABC transporter complex possibly involved in cobalt import. Responsible for energy coupling to the transport system.; importer ATP-binding protein 406700..408094 Streptococcus equi subsp. zooepidemicus MGCS10565 6760476 YP_002122770.1 CDS recG NC_011134.1 408472 410487 D similar to ref|NP_722150.1| ATP-dependent DNA helicase, RecG [Streptococcus mutans UA159]; Critical role in recombination and DNA repair. Help process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3' to 5' polarity. RecG unwind branched duplex DNA (Y-DNA).; ATP-dependent DNA helicase RecG 408472..410487 Streptococcus equi subsp. zooepidemicus MGCS10565 6760714 YP_002122771.1 CDS ansA NC_011134.1 410608 411531 R similar to ref|NP_269796.1| L-asparaginase [Streptococcus pyogenes M1 GAS]; Catalysis of the reaction: L-asparagine + H2O = L-aspartate + NH3.; L-asparaginase complement(410608..411531) Streptococcus equi subsp. zooepidemicus MGCS10565 6760475 YP_002122772.1 CDS Sez_0383 NC_011134.1 411645 413033 D similar to ref|ZP_00365596.1| COG0561: Predicted hydrolases of the HAD superfamily [Streptococcus pyogenes M49 591]; hydrolase 411645..413033 Streptococcus equi subsp. zooepidemicus MGCS10565 6760711 YP_002122773.1 CDS Sez_0384 NC_011134.1 413320 413748 R similar to ref|YP_280968.1| universal stress protein family [Streptococcus pyogenes MGAS6180]; universal stress protein complement(413320..413748) Streptococcus equi subsp. zooepidemicus MGCS10565 6760474 YP_002122774.1 CDS codY NC_011134.1 415432 416214 D CodY; DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase (By similarity). It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor; transcriptional repressor CodY 415432..416214 Streptococcus equi subsp. zooepidemicus MGCS10565 6760473 YP_002122775.1 CDS Sez_0388 NC_011134.1 416842 417399 D similar to ref|YP_001034560.1| Isochorismitase family protein, [Streptococcus sanguinis SK36]; Catalysis of the reaction: nicotinamide + H2O = nicotinate + NH3.; pyrazinamidase/nicotinamidase 416842..417399 Streptococcus equi subsp. zooepidemicus MGCS10565 6760707 YP_002122776.1 CDS gatC NC_011134.1 417881 418183 D allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; some Mycoplasma proteins contain an N-terminal fusion to an unknown domain; aspartyl/glutamyl-tRNA amidotransferase subunit C 417881..418183 Streptococcus equi subsp. zooepidemicus MGCS10565 6760471 YP_002122777.1 CDS gatA NC_011134.1 418183 419649 D allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; aspartyl/glutamyl-tRNA amidotransferase subunit A 418183..419649 Streptococcus equi subsp. zooepidemicus MGCS10565 6760705 YP_002122778.1 CDS gatB NC_011134.1 419649 421088 D allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; aspartyl/glutamyl-tRNA amidotransferase subunit B 419649..421088 Streptococcus equi subsp. zooepidemicus MGCS10565 6760470 YP_002122779.1 CDS Sez_0392 NC_011134.1 421317 422261 D similar to ref|YP_820933.1| permease of the drug/metabolite transporter (DMT) superfamily [Streptococcus thermophilus LMD-9]; drug/metabolite transporter (DMT) superfamily protein 421317..422261 Streptococcus equi subsp. zooepidemicus MGCS10565 6760703 YP_002122780.1 CDS Sez_0393 NC_011134.1 422309 422551 D similar to ref|YP_060816.1| Hypothetical membrane spanning protein [Streptococcus pyogenes MGAS10394]; hypothetical protein 422309..422551 Streptococcus equi subsp. zooepidemicus MGCS10565 6760469 YP_002122781.1 CDS sfs NC_011134.1 422760 423767 D similar to gb|AAD29424.1|AF136451_1 fibronectin-binding protein SFS [Streptococcus equi]; secreted adhesin, however lacks canonical secretion signal sequence. Has some similarity with the eukaryotic ECM protein, repetin.; fibronectin-binding protein Sfs-like 422760..423767 Streptococcus equi subsp. zooepidemicus MGCS10565 6760701 YP_002122782.1 CDS Sez_0395 NC_011134.1 424032 424298 D ACT domain-containing protein; hypothetical protein 424032..424298 Streptococcus equi subsp. zooepidemicus MGCS10565 6760468 YP_002122783.1 CDS Sez_0396 NC_011134.1 424313 425650 D similar to ref|YP_001449706.1| glycerol-3-phosphate dehydrogenase (NAD(P)+) [Streptococcus gordonii str. Challis substr. CH1]; De novo phospholipid biosynthesis; glycerol-3 phosphate formation.; hypothetical protein 424313..425650 Streptococcus equi subsp. zooepidemicus MGCS10565 6760698 YP_002122784.1 CDS Sez_0397 NC_011134.1 425767 426432 D similar to ref|NP_607855.1| phosphoglycerate mutase [Streptococcus pyogenes MGAS8232]; phosphoglycerate mutase 425767..426432 Streptococcus equi subsp. zooepidemicus MGCS10565 6760467 YP_002122785.1 CDS Sez_0398 NC_011134.1 426422 427165 D similar to ref|NP_607854.1| D,D-carboxypeptidase [Streptococcus pyogenes MGAS8232]; Vancomycin-inducible, penicillin-resistant, DD- carboxypeptidase that hydrolyzes depsipeptide- and D-alanyl-D- alanine-containing peptidoglycan precursors. Insensitive to beta- lactams.; D-alanyl-D-alanine carboxypeptidase 426422..427165 Streptococcus equi subsp. zooepidemicus MGCS10565 6760695 YP_002122786.1 CDS Sez_0399 NC_011134.1 427213 427698 D similar to ref|NP_607853.1| N-acetyl-muramidase [Streptococcus pyogenes MGAS8232]; N-acetyl-muramidase 427213..427698 Streptococcus equi subsp. zooepidemicus MGCS10565 6760466 YP_002122787.1 CDS hrcA NC_011134.1 428181 429215 D Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons; heat-inducible transcription repressor 428181..429215 Streptococcus equi subsp. zooepidemicus MGCS10565 6760693 YP_002122788.1 CDS grpE NC_011134.1 429260 429829 D with DnaK and DnaJ acts in response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins; may act as a thermosensor; heat shock protein GrpE 429260..429829 Streptococcus equi subsp. zooepidemicus MGCS10565 6760465 YP_002122789.1 CDS dnaK NC_011134.1 430217 432070 D heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria; molecular chaperone DnaK 430217..432070 Streptococcus equi subsp. zooepidemicus MGCS10565 6760691 YP_002122790.1 CDS dnaJ NC_011134.1 432227 433363 D chaperone Hsp40; co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion; molecular chaperone DnaJ 432227..433363 Streptococcus equi subsp. zooepidemicus MGCS10565 6760464 YP_002122791.1 CDS Sez_0404 NC_011134.1 433621 434481 D Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; enoyl-CoA hydratase 433621..434481 Streptococcus equi subsp. zooepidemicus MGCS10565 6760688 YP_002122792.1 CDS Sez_0405 NC_011134.1 434561 434995 D similar to ref|YP_280949.1| transcriptional regulator, MarR family [Streptococcus pyogenes MGAS6180]; Transcriptional repressor.; transcriptional regulator of fatty acid biosynthesis FabT 434561..434995 Streptococcus equi subsp. zooepidemicus MGCS10565 6760463 YP_002122793.1 CDS Sez_0406 NC_011134.1 434995 435969 D FabH; beta-ketoacyl-acyl carrier protein synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs; 3-oxoacyl-ACP synthase 434995..435969 Streptococcus equi subsp. zooepidemicus MGCS10565 6760685 YP_002122794.1 CDS acpP NC_011134.1 436027 436251 D carries the fatty acid chain in fatty acid biosynthesis; acyl carrier protein 436027..436251 Streptococcus equi subsp. zooepidemicus MGCS10565 6760461 YP_002122795.1 CDS Sez_0408 NC_011134.1 436446 437432 D similar to ref|NP_269774.1| trans-2-enoyl-ACP reductase II [Streptococcus pyogenes M1 GAS]; Catalysis of the reaction: acyl-[acyl-carrier protein] + NAD+ = trans-2,3-dehydroacyl-[acyl-carrier protein] + NADH + H+.; enoyl-ACP reductase 436446..437432 Streptococcus equi subsp. zooepidemicus MGCS10565 6760683 YP_002122796.1 CDS fabD NC_011134.1 437445 438365 D similar to ref|NP_269773.1| acyl-carrier-protein S-malonyltransferase [Streptococcus pyogenes M1 GAS]; Fatty acid biosynthesis.; malonyl CoA-ACP transacylase 437445..438365 Streptococcus equi subsp. zooepidemicus MGCS10565 6760460 YP_002122797.1 CDS fabG NC_011134.1 438382 439116 D catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis; 3-ketoacyl-ACP reductase 438382..439116 Streptococcus equi subsp. zooepidemicus MGCS10565 6760679 YP_002122798.1 CDS fabF NC_011134.1 439132 440364 D FabF; beta-ketoacyl-ACP synthase II, KASII; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP; 3-oxoacyl-ACP synthase 439132..440364 Streptococcus equi subsp. zooepidemicus MGCS10565 6760459 YP_002122799.1 CDS accB NC_011134.1 440366 440839 D composes the biotin carboxyl carrier protein subunit of the acetyl-CoA carboxylase complex, the enzyme that catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, which in turn controls the rate of fatty acid metabolism; acetyl-CoA carboxylase biotin carboxyl carrier protein subunit 440366..440839 Streptococcus equi subsp. zooepidemicus MGCS10565 6760676 YP_002122800.1 CDS fabZ NC_011134.1 440836 441258 D in Pseudomonas aeruginosa this enzyme is a trimer of dimers; essential for membrane formation; performs third step of type II fatty acid biosynthesis; catalyzes dehydration of (3R)-hydroxyacyl-ACP to trans-2-acyl-ACP; (3R)-hydroxymyristoyl-ACP dehydratase 440836..441258 Streptococcus equi subsp. zooepidemicus MGCS10565 6760458 YP_002122801.1 CDS accD NC_011134.1 442665 443531 D catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer of AccA2D2 subunits; acetyl-CoA carboxylase subunit beta 442665..443531 Streptococcus equi subsp. zooepidemicus MGCS10565 6760457 YP_002122802.1 CDS accA NC_011134.1 443528 444298 D catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer composed of two alpha (AccA) and two beta (AccD) subunits; one of the two catalytic subunits that can form the acetyl CoA carboxylase enzyme together with a carrier protein; these proteins present a shorter N-terminus; acetyl-CoA carboxylase subunit alpha 443528..444298 Streptococcus equi subsp. zooepidemicus MGCS10565 6760672 YP_002122803.1 CDS serS NC_011134.1 444529 445806 R catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; seryl-tRNA synthetase complement(444529..445806) Streptococcus equi subsp. zooepidemicus MGCS10565 6760456 YP_002122804.1 CDS Sez_0419 NC_011134.1 446391 447458 D similar to ref|NP_734813.1| hypothetical protein gbs0344 [Streptococcus agalactiae NEM316]; hypothetical protein 446391..447458 Streptococcus equi subsp. zooepidemicus MGCS10565 6760670 YP_002122805.1 CDS manO NC_011134.1 447626 448009 R similar to ref|YP_280936.1| hypothetical cytosolic protein [Streptococcus pyogenes MGAS6180]; mannose operon regulator ManO complement(447626..448009) Streptococcus equi subsp. zooepidemicus MGCS10565 6760455 YP_002122806.1 CDS manZ NC_011134.1 448143 449054 R similar to ref|NP_607833.1| mannose-specific phosphotransferase system component IID [Streptococcus pyogenes MGAS8232]; This is a component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (Pts), a major carbohydrate active -transport system.; mannose-Specific Phosphotransferase System Component IID ManZ complement(448143..449054) Streptococcus equi subsp. zooepidemicus MGCS10565 6760668 YP_002122807.1 CDS manY NC_011134.1 449070 449879 R similar to ref|YP_280934.1| PTS system, mannose-specific IIC component [Streptococcus pyogenes MGAS6180]; PTS system mannose-specific transporter subunit IIC complement(449070..449879) Streptococcus equi subsp. zooepidemicus MGCS10565 6760454 YP_002122808.1 CDS manX NC_011134.1 450047 451039 R similar to ref|YP_001127956.1| mannose-specific phosphotransferase system (PTS), IIAB component [Streptococcus pyogenes str. Manfredo]; The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. This system is involved in mannose transport.; PTS system mannose-specific transporter subunit IIAB complement(450047..451039) Streptococcus equi subsp. zooepidemicus MGCS10565 6760666 YP_002122809.1 CDS Sez_0424 NC_011134.1 451167 451394 R similar to ref|XP_954798.1| glutamate-cysteine ligase, [Theileria annulata strain Ankara]; hypothetical protein complement(451167..451394) Streptococcus equi subsp. zooepidemicus MGCS10565 6760453 YP_002122810.1 CDS Sez_0425 NC_011134.1 451391 452203 R similar to ref|NP_607830.1| hypothetical protein spyM18_1809 [Streptococcus pyogenes MGAS8232]; hydrolase complement(451391..452203) Streptococcus equi subsp. zooepidemicus MGCS10565 6760663 YP_002122811.1 CDS Sez_0426 NC_011134.1 452462 453922 D similar to ref|YP_060789.1| Guanine-hypoxanthine permease [Streptococcus pyogenes MGAS10394]; guanine-hypoxanthine permease 452462..453922 Streptococcus equi subsp. zooepidemicus MGCS10565 6760452 YP_002122812.1 CDS Sez_0427 NC_011134.1 454291 454734 D similar to ref|NP_720857.1| hypothetical protein SMU.409 [Streptococcus mutans UA159]; Similar to ATPase YjeE, predicted to have essential role in cell wall biosynthesis.; ATP/GTP hydrolase 454291..454734 Streptococcus equi subsp. zooepidemicus MGCS10565 6760661 YP_002122813.1 CDS Sez_0428 NC_011134.1 454727 455254 D similar to ref|NP_607771.1| hypothetical protein spyM18_1742 [Streptococcus pyogenes MGAS8232]; acetyltransferase GNAT Family 454727..455254 Streptococcus equi subsp. zooepidemicus MGCS10565 6760451 YP_002122814.1 CDS lytR NC_011134.1 455255 456517 D similar to ref|YP_060786.1| Transcriptional regulator, LytR family [Streptococcus pyogenes MGAS10394]; Attenuator role for operon expression.; LytR family transcriptional regulator 455255..456517 Streptococcus equi subsp. zooepidemicus MGCS10565 6760659 YP_002122815.1 CDS Sez_0430 NC_011134.1 456681 456983 R similar to ref|NP_607769.1| hypothetical protein spyM18_1739 [Streptococcus pyogenes MGAS8232]; hypothetical protein complement(456681..456983) Streptococcus equi subsp. zooepidemicus MGCS10565 6760450 YP_002122816.1 CDS hit NC_011134.1 456980 457399 R similar to ref|NP_269754.1| cell-cycle regulation histidine triad (HIT) protein [Streptococcus pyogenes M1 GAS]; cell-cycle regulation histidine triad protein HIT complement(456980..457399) Streptococcus equi subsp. zooepidemicus MGCS10565 6760657 YP_002122817.1 CDS Sez_0432 NC_011134.1 457851 458147 R similar to ref|YP_040351.1| hypothetical protein SAR0929 [Staphylococcus aureus subsp. aureus MRSA252]; hypothetical protein complement(457851..458147) Streptococcus equi subsp. zooepidemicus MGCS10565 6760449 YP_002122818.1 CDS Sez_0433 NC_011134.1 458445 458588 R hypothetical protein complement(458445..458588) Streptococcus equi subsp. zooepidemicus MGCS10565 6760654 YP_002122819.1 CDS ecsA NC_011134.1 458684 459388 D similar to ref|YP_280925.1| ABC-type transporter ATP-binding protein ecsA [Streptococcus pyogenes MGAS6180]; Has a role in exoprotein production, sporulation and competence.; ABC transporter ATP-binding protein 458684..459388 Streptococcus equi subsp. zooepidemicus MGCS10565 6760448 YP_002122820.1 CDS ecsB NC_011134.1 459412 460446 D similar to ref|YP_060782.1| EcsB [Streptococcus pyogenes MGAS10394]; Strain 3610 ecsB deletion mutant forms colonies in which certain architectural features are absent or less prominent than those observed in wild-type colonies. The Ecs activity could be important for the development of communities.; EcsB 459412..460446 Streptococcus equi subsp. zooepidemicus MGCS10565 6760652 YP_002122821.1 CDS Sez_0436 NC_011134.1 460509 461300 D similar to ref|YP_060781.1| Phosphotransferase enzyme family [Streptococcus pyogenes MGAS10394]; aminoglycoside phosphotransferase 460509..461300 Streptococcus equi subsp. zooepidemicus MGCS10565 6760447 YP_002122822.1 CDS trmB NC_011134.1 461300 461935 D tRNA (guanine-N(7)-)-methyltransferase; catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA by transferring the methyl residue from S-adenosyl-L-methionine; tRNA (guanine-N(7)-)-methyltransferase 461300..461935 Streptococcus equi subsp. zooepidemicus MGCS10565 6760650 YP_002122823.1 CDS Sez_0438 NC_011134.1 462131 462283 R similar to ref|YP_282830.1| Gene info phi5005.3 integrase [Streptococcus pyogenes phage 5005.3]; phage integrase-like protein complement(462131..462283) Streptococcus equi subsp. zooepidemicus MGCS10565 6760816 YP_002122824.1 CDS Sez_0439 NC_011134.1 463417 463800 D in Streptococcus pneumoniae this gene was found to be essential; structure determination of the Streptococcus protein shows that it is similar to a number of other proteins; hypothetical protein 463417..463800 Streptococcus equi subsp. zooepidemicus MGCS10565 6760648 YP_002122825.1 CDS nusA NC_011134.1 463910 465064 D modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination; transcription elongation factor NusA 463910..465064 Streptococcus equi subsp. zooepidemicus MGCS10565 6760445 YP_002122826.1 CDS Sez_0441 NC_011134.1 465080 465376 D similar to ref|YP_060777.1| Hypothetical cytosolic protein [Streptococcus pyogenes MGAS10394]; COG2740: Predicted nucleic-acid-binding protein implicated in transcription termination.; hypothetical protein 465080..465376 Streptococcus equi subsp. zooepidemicus MGCS10565 6760646 YP_002122827.1 CDS Sez_0442 NC_011134.1 465396 465671 D similar to ref|NP_607760.1| hypothetical protein spyM18_1730 [Streptococcus pyogenes MGAS8232]; ribosomal protein L7Ae family protein 465396..465671 Streptococcus equi subsp. zooepidemicus MGCS10565 6760444 YP_002122828.1 CDS infB NC_011134.1 465691 468534 D Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; translation initiation factor IF-2 465691..468534 Streptococcus equi subsp. zooepidemicus MGCS10565 6760644 YP_002122829.1 CDS Sez_0444 NC_011134.1 468585 468725 R hypothetical protein complement(468585..468725) Streptococcus equi subsp. zooepidemicus MGCS10565 6760443 YP_002122830.1 CDS rbfA NC_011134.1 468724 469074 D associates with free 30S ribosomal subunits; essential for efficient processing of 16S rRNA; in Escherichia coli rbfA is induced by cold shock; ribosome-binding factor A 468724..469074 Streptococcus equi subsp. zooepidemicus MGCS10565 6760642 YP_002122831.1 CDS Sez_0446 NC_011134.1 469146 470183 R similar to ref|ZP_00365884.1| COG0657: Esterase/lipase [Streptococcus pyogenes M49 591]; Unknown, similar to beta lactamases, possibly involved in PG maturation.; esterase complement(469146..470183) Streptococcus equi subsp. zooepidemicus MGCS10565 6760442 YP_002122832.1 CDS Sez_0447 NC_011134.1 470413 470847 D similar to ref|YP_280914.1| copAB ATPase metal-fist type repressor [Streptococcus pyogenes MGAS6180]; negative transcriptional regulator-copper transport operon 470413..470847 Streptococcus equi subsp. zooepidemicus MGCS10565 6760640 YP_002122833.1 CDS pacS NC_011134.1 470817 473078 D similar to ref|YP_597138.1| copper-exporting ATPase [Streptococcus pyogenes MGAS9429]; May play a role in the osmotic adaptation.; copper-translocating P-type ATPase PacS 470817..473078 Streptococcus equi subsp. zooepidemicus MGCS10565 6760441 YP_002122834.1 CDS Sez_0449 NC_011134.1 473474 473596 R hypothetical protein complement(473474..473596) Streptococcus equi subsp. zooepidemicus MGCS10565 6760638 YP_002122835.1 CDS Sez_0450 NC_011134.1 473949 474899 D similar to ref|YP_001052596.1| hypothetical protein Sbal_4262 [Shewanella baltica OS155]; Unknown, possible galanin.; hypothetical protein 473949..474899 Streptococcus equi subsp. zooepidemicus MGCS10565 6760440 YP_002122836.1 CDS Sez_0451 NC_011134.1 474912 475463 D similar to ref|YP_001395827.1| hypothetical protein CKL_2444 [Clostridium kluyveri DSM 555]; The members of this family are related to the LemA protein . LemA contains an N-terminal predicted transmembrane helix. It has been predicted that the small N terminus is extracellular. The exact molecular function of this protein is uncertain.; LemA family protein 474912..475463 Streptococcus equi subsp. zooepidemicus MGCS10565 6760636 YP_002122837.1 CDS lacR NC_011134.1 475879 476661 R similar to ref|YP_597136.1| lactose phosphotransferase system repressor [Streptococcus pyogenes MGAS9429]; Repressor of the lactose catabolism operon. Galactose-6- phosphate is the inducer.; lactose phosphotransferase system repressor LacR complement(475879..476661) Streptococcus equi subsp. zooepidemicus MGCS10565 6760439 YP_002122838.1 CDS lacA NC_011134.1 476862 477287 D catalyzes the interconversion of galactose 6-phosphate to tagatose; galactose-6-phosphate isomerase subunit LacA 476862..477287 Streptococcus equi subsp. zooepidemicus MGCS10565 6761368 YP_002122839.1 CDS lacB NC_011134.1 477303 477818 D catalyzes the interconversion of galactose 6-phosphate to tagatose 6-phosphate; galactose-6-phosphate isomerase subunit LacB 477303..477818 Streptococcus equi subsp. zooepidemicus MGCS10565 6761366 YP_002122840.1 CDS lacC NC_011134.1 477827 478759 D similar to ref|YP_417532.1| tagatose-6-phosphate kinase [Staphylococcus aureus RF122]; Catalysis of the reaction: ATP + D-fructose 1-phosphate = ADP + D-fructose 1,6-bisphosphate; tagatose-6-phosphate kinase LacC 477827..478759 Streptococcus equi subsp. zooepidemicus MGCS10565 6761348 YP_002122841.1 CDS lacD NC_011134.1 478761 479753 D catalyzes the reversible reaction of dihydroxyacetone phosphate with glyceraldehyde 3-phosphate to produce tagatose 1,6-bisphosphate; in Streptococcus pyogenes there are two paralogs of tagatose-bisphosphate aldolase, encoded by lacD1 and lacD2; expression of lacD1 is highly regulated by environmental conditions while lacD2 specializes in an efficient utilization of carbohydrate sources; tagatose 1,6-diphosphate aldolase 478761..479753 Streptococcus equi subsp. zooepidemicus MGCS10565 6761363 YP_002122842.1 CDS Sez_0457 NC_011134.1 479789 479914 D hypothetical protein 479789..479914 Streptococcus equi subsp. zooepidemicus MGCS10565 6761361 YP_002122843.1 CDS lacT NC_011134.1 480030 480881 D similar to ref|YP_001198405.1| Transcriptional antiterminator [Streptococcus suis 05ZYH33]; Mediates positive regulation of the lac operon by functioning as an antiterminator factor of transcription.; transcription antiterminator LacT 480030..480881 Streptococcus equi subsp. zooepidemicus MGCS10565 6761360 YP_002122844.1 CDS lacF NC_011134.1 480892 481203 D similar to ref|YP_001198404.1| Phosphotransferase system cellobiose-specific component IIA [Streptococcus suis 05ZYH33]; The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. This system is involved in lactose transport.; lactose-specific phosphotransferase enzyme IIA component LacF 480892..481203 Streptococcus equi subsp. zooepidemicus MGCS10565 6761353 YP_002122845.1 CDS lacE NC_011134.1 481207 482889 D similar to ref|YP_599311.1| PTS system, lactose-specific IIBC component [Streptococcus pyogenes MGAS10270]; The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. This system is involved in lactose transport.; PTS system lactose-specific transporter subunit IIBC 481207..482889 Streptococcus equi subsp. zooepidemicus MGCS10565 6761352 YP_002122846.1 CDS lacG NC_011134.1 482899 484308 D catalyzes the formation of 6-phospho-galactose from a 6-phospho-beta-galactoside; 6-phospho-beta-galactosidase 482899..484308 Streptococcus equi subsp. zooepidemicus MGCS10565 6761327 YP_002122847.1 CDS Sez_0462 NC_011134.1 484516 485391 D similar to ref|NP_973373.1| lipoprotein, [Treponema denticola ATCC 35405]; membrane associated protein 484516..485391 Streptococcus equi subsp. zooepidemicus MGCS10565 6761340 YP_002122848.1 CDS Sez_0463 NC_011134.1 485549 486151 D similar to ref|YP_060761.1| Hypothetical membrane spanning protein [Streptococcus pyogenes MGAS10394]; rhomboid family integral membrane protein 485549..486151 Streptococcus equi subsp. zooepidemicus MGCS10565 6761339 YP_002122849.1 CDS Sez_0464 NC_011134.1 486156 486980 D similar to ref|NP_607744.1| hypothetical protein spyM18_1711 [Streptococcus pyogenes MGAS8232]; HAD superfamily hydrolase 486156..486980 Streptococcus equi subsp. zooepidemicus MGCS10565 6761338 YP_002122850.1 CDS Sez_0465 NC_011134.1 487390 487947 R similar to ref|YP_060759.1| Transcriptional regulator, TetR family [Streptococcus pyogenes MGAS10394]; TetR family transcriptional regulator complement(487390..487947) Streptococcus equi subsp. zooepidemicus MGCS10565 6761313 YP_002122851.1 CDS Sez_0466 NC_011134.1 488079 488921 D similar to ref|YP_060758.1| DegV family protein [Streptococcus pyogenes MGAS10394]; The structure of this protein revealed a bound fatty-acid molecule in a pocket between the two protein domains. The structure indicates that this family has the molecular function of fatty-acid binding and may play a role in the cellular functions of fatty acid transport or metabolism.; DegV family protein 488079..488921 Streptococcus equi subsp. zooepidemicus MGCS10565 6761326 YP_002122852.1 CDS Sez_0467 NC_011134.1 489065 489205 D hypothetical protein 489065..489205 Streptococcus equi subsp. zooepidemicus MGCS10565 6761304 YP_002122853.1 CDS rbsR NC_011134.1 489192 490175 D similar to ref|NP_664990.1| ribose transport operon repressor [Streptococcus pyogenes MGAS315]; Transcriptional repressor for the ribose rbsDACBK operon.; ribose operon repressor RbsR 489192..490175 Streptococcus equi subsp. zooepidemicus MGCS10565 6761320 YP_002122854.1 CDS rbsK NC_011134.1 490201 491079 D similar to ref|ZP_00783282.1| ribokinase [Streptococcus agalactiae H36B]; Ribose metabolism; first step.; ribokinase RbsK 490201..491079 Streptococcus equi subsp. zooepidemicus MGCS10565 6761319 YP_002122855.1 CDS rbsD NC_011134.1 491045 491452 D cytoplasmic mutarotase that catalyzes the conversion between beta-pyran and beta-furan forms of D-ribose; RbsD is required for efficient ribose utilization in E. coli; rbsD-mutant E. coli strains are unable to use ribose as a sole carbon source; D-ribose pyranase 491045..491452 Streptococcus equi subsp. zooepidemicus MGCS10565 6761314 YP_002122856.1 CDS rbsA NC_011134.1 491468 492946 D similar to ref|YP_328841.1| ribose ABC transporter, ATP-binding protein [Streptococcus agalactiae A909]; Part of the binding-protein-dependent transport system for ribose. Probably responsible for energy coupling to the transport system.; ribose transport ATP-binding protein RbsA 491468..492946 Streptococcus equi subsp. zooepidemicus MGCS10565 6761281 YP_002122857.1 CDS rbsC NC_011134.1 492948 493889 D similar to ref|ZP_00783299.1| ribose ABC transporter, permease [Streptococcus agalactiae H36B]; Part of the binding-protein-dependent transport system for ribose. Probably responsible for the translocation of the substrate across the membrane.; ribose transport system permease RbsC 492948..493889 Streptococcus equi subsp. zooepidemicus MGCS10565 6761312 YP_002122858.1 CDS rbsB NC_011134.1 493904 494872 D similar to ref|YP_328839.1| ribose ABC transporter, ribose-binding protein [Streptococcus agalactiae A909]; Involved in the high-affinity D-ribose membrane transport system.; D-ribose-binding protein precursor RbsB 493904..494872 Streptococcus equi subsp. zooepidemicus MGCS10565 6761311 YP_002122859.1 CDS Sez_0474 NC_011134.1 495181 495351 D hypothetical protein 495181..495351 Streptococcus equi subsp. zooepidemicus MGCS10565 6761277 YP_002122860.1 CDS Sez_0475 NC_011134.1 495492 496244 R similar to ref|YP_597122.1| hypothetical protein MGAS9429_Spy1390 [Streptococcus pyogenes MGAS9429]; Has carboxy terminal proline rich repeat motif.; hypothetical protein complement(495492..496244) Streptococcus equi subsp. zooepidemicus MGCS10565 6761309 YP_002122861.1 CDS Sez_0476 NC_011134.1 496435 498066 D similar to ref|YP_597120.1| sodium-dependent phosphate transporter [Streptococcus pyogenes MGAS9429]; Na/Pi-cotransporter family protein 496435..498066 Streptococcus equi subsp. zooepidemicus MGCS10565 6761307 YP_002122862.1 CDS manD NC_011134.1 498183 499331 D similar to ref|YP_001127991.1| N-acetylglucosamine-6-phosphate deacetylase [Streptococcus pyogenes str. Manfredo]; Catalysis of the reaction: N-acetyl-D-glucosamine 6-phosphate + H2O = D-glucosamine 6-phosphate + acetate.; N-acetylglucosamine-6-phosphate deacetylase 498183..499331 Streptococcus equi subsp. zooepidemicus MGCS10565 6761308 YP_002122863.1 CDS Sez_0478 NC_011134.1 499418 500257 D similar to ref|YP_597118.1| aldo/keto reductase family [Streptococcus pyogenes MGAS9429]; Catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced.; 2,5-diketo-D-gluconic acid reductase 499418..500257 Streptococcus equi subsp. zooepidemicus MGCS10565 6761272 YP_002122864.1 CDS Sez_0479 NC_011134.1 500528 500911 D similar to gb|ABO37817.1| unknown [Lactococcus garvieae]; hypothetical protein 500528..500911 Streptococcus equi subsp. zooepidemicus MGCS10565 6761301 YP_002122865.1 CDS Sez_0480 NC_011134.1 500835 501887 D similar to ref|YP_001485591.1| hypothetical membrane protein [Bacillus pumilus SAFR-032]; hypothetical protein 500835..501887 Streptococcus equi subsp. zooepidemicus MGCS10565 6761300 YP_002122866.1 CDS Sez_0481 NC_011134.1 501884 503131 D similar to ref|YP_035932.1| conserved hypothetical protein, possible permease [Bacillus thuringiensis serovar konkukian str. 97-27]; permease 501884..503131 Streptococcus equi subsp. zooepidemicus MGCS10565 6761299 YP_002122867.1 CDS Sez_0482 NC_011134.1 503151 503783 D similar to ref|YP_001642502.1| ABC transporter related [Bacillus weihenstephanensis KBAB4]; Part of the ABC transporter complex possibly involved in bacitracin export. Responsible for energy coupling to the transport system.; export ATP-binding protein 503151..503783 Streptococcus equi subsp. zooepidemicus MGCS10565 6761296 YP_002122868.1 CDS Sez_0483 NC_011134.1 503752 503913 D hypothetical protein 503752..503913 Streptococcus equi subsp. zooepidemicus MGCS10565 6761295 YP_002122869.1 CDS Sez_0484 NC_011134.1 504050 504583 D similar to ref|YP_280894.1| hypothetical membrane spanning protein [Streptococcus pyogenes MGAS6180]; hypothetical protein 504050..504583 Streptococcus equi subsp. zooepidemicus MGCS10565 6761294 YP_002122870.1 CDS Sez_0485 NC_011134.1 504820 504972 R hypothetical protein complement(504820..504972) Streptococcus equi subsp. zooepidemicus MGCS10565 6761280 YP_002122871.1 CDS glyQ NC_011134.1 504971 505882 D glycine--tRNA ligase alpha chain; GlyRS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; glycyl-tRNA synthetase subunit alpha 504971..505882 Streptococcus equi subsp. zooepidemicus MGCS10565 6761291 YP_002122872.1 CDS glyS NC_011134.1 506249 508291 D glycine--tRNA ligase beta chain; glyS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; glycyl-tRNA synthetase subunit beta 506249..508291 Streptococcus equi subsp. zooepidemicus MGCS10565 6761279 YP_002122873.1 CDS Sez_0488 NC_011134.1 508284 508415 R hypothetical protein complement(508284..508415) Streptococcus equi subsp. zooepidemicus MGCS10565 6761276 YP_002122874.1 CDS Sez_0489 NC_011134.1 508829 509086 D similar to ref|NP_269721.1| hypothetical protein SPy_1687 [Streptococcus pyogenes M1 GAS]; hypothetical protein 508829..509086 Streptococcus equi subsp. zooepidemicus MGCS10565 6761289 YP_002122875.1 CDS sagA NC_011134.1 509615 509776 D similar to gb|AAC19115.1| streptolysin S associated protein SagA [Streptococcus pyogenes]; Hemolysin/cytolysin.; SagA precursor 509615..509776 Streptococcus equi subsp. zooepidemicus MGCS10565 6761287 YP_002122876.1 CDS sagB NC_011134.1 510004 510954 D similar to gb|AAK53984.1| SagB [Streptococcus dysgalactiae subsp. equisimilis]; Involved in streptolysin S synthesis/transport/immunity.; Streptolysin S biosynthesis protein SagB 510004..510954 Streptococcus equi subsp. zooepidemicus MGCS10565 6761275 YP_002122877.1 CDS sagC NC_011134.1 510951 512015 D similar to gb|AAN16973.1|AF465842_3 SagC [Streptococcus iniae]; Involved in streptolysin S synthesis/transport/immunity.; Streptolysin S biosynthesis protein SagC 510951..512015 Streptococcus equi subsp. zooepidemicus MGCS10565 6761256 YP_002122878.1 CDS sagD NC_011134.1 512028 513386 D similar to ref|YP_598228.1| Streptolysin S biosynthesis protein SagD [Streptococcus pyogenes MGAS10270]; Involved in streptolysin S synthesis/transport/immunity.; Streptolysin S biosynthesis protein SagD 512028..513386 Streptococcus equi subsp. zooepidemicus MGCS10565 6761271 YP_002122879.1 CDS sagE NC_011134.1 513427 514032 D similar to gb|AAN16975.1|AF465842_5 SagE [Streptococcus iniae]; Involved in streptolysin S synthesis/transport/immunity.; Streptolysin S self-immunity protein SagE 513427..514032 Streptococcus equi subsp. zooepidemicus MGCS10565 6761253 YP_002122880.1 CDS sagF NC_011134.1 514029 514715 D similar to gb|AAN16976.1|AF465842_6 SagF [Streptococcus iniae]; Involved in streptolysin S synthesis/transport/immunity.; Streptolysin S biosynthesis protein SagF 514029..514715 Streptococcus equi subsp. zooepidemicus MGCS10565 6761250 YP_002122881.1 CDS sagG NC_011134.1 514738 515661 D similar to gb|AAN16977.1|AF465842_7 SagG [Streptococcus iniae]; Involved in streptolysin S synthesis/transport/immunity.; export ABC transporter ATP-binding protein; Streptolysin S export protein SagG 514738..515661 Streptococcus equi subsp. zooepidemicus MGCS10565 6761249 YP_002122882.1 CDS sagH NC_011134.1 515670 516797 D similar to gb|AAN16978.1|AF465842_8 SagH [Streptococcus iniae]; Involved in streptolysin S synthesis/transport/immunity.; Streptolysin S export transmembrane permease SagH 515670..516797 Streptococcus equi subsp. zooepidemicus MGCS10565 6761248 YP_002122883.1 CDS sagI NC_011134.1 516794 517912 D similar to gb|AAN16979.1|AF465842_9 SagI [Streptococcus iniae]; Involved in streptolysin S synthesis/transport/immunity.; Streptolysin S export transmembrane permease SagI 516794..517912 Streptococcus equi subsp. zooepidemicus MGCS10565 6761266 YP_002122884.1 CDS fbpZ.2 NC_011134.1 518045 519493 R similar to ref|NP_001105492.1| proline-rich protein [Zea mays]; fibronectin-binding protein FbpZ.2 complement(518045..519493) Streptococcus equi subsp. zooepidemicus MGCS10565 6761267 YP_002122885.1 CDS sclZ.6 NC_011134.1 519809 521377 R similar to gb|ABA41496.1| collagen-like protein F [Streptococcus equi subsp. equi]; Possible fibronectin-binding adhesin, has a collagen-structural-motif domain composed of 51 Gly-Xaa-Yaa repeats.; hypothetical protein complement(519809..521377) Streptococcus equi subsp. zooepidemicus MGCS10565 6761261 YP_002122886.1 CDS Sez_0501 NC_011134.1 521396 521521 R hypothetical protein complement(521396..521521) Streptococcus equi subsp. zooepidemicus MGCS10565 6761241 YP_002122887.1 CDS Sez_0502 NC_011134.1 521527 521658 D hypothetical protein 521527..521658 Streptococcus equi subsp. zooepidemicus MGCS10565 6761260 YP_002122888.1 CDS Sez_0503 NC_011134.1 521790 522875 R similar to gb|AAN18300.1| lipoprotein [Streptococcus equi]; hypothetical protein complement(521790..522875) Streptococcus equi subsp. zooepidemicus MGCS10565 6761239 YP_002122889.1 CDS Sez_0504 NC_011134.1 523112 523240 D hypothetical protein 523112..523240 Streptococcus equi subsp. zooepidemicus MGCS10565 6761232 YP_002122890.1 CDS cutC NC_011134.1 523347 523976 R similar to gb|AAN18302.1| Se22.9 [Streptococcus equi]; Involved in copper homeostasis.; copper homeostasis protein CutC-like complement(523347..523976) Streptococcus equi subsp. zooepidemicus MGCS10565 6761236 YP_002122891.1 CDS Sez_0506 NC_011134.1 524187 524741 D similar to gb|AAN18301.1| acetyltransferase [Streptococcus equi]; GNAT family acetyltransferase 524187..524741 Streptococcus equi subsp. zooepidemicus MGCS10565 6761245 YP_002122892.1 CDS Sez_0507 NC_011134.1 525216 526346 D similar to ref|YP_596508.1| transposase [Streptococcus pyogenes MGAS9429]; transposase IS1548-like 525216..526346 Streptococcus equi subsp. zooepidemicus MGCS10565 6761246 YP_002122893.1 CDS Sez_0508 NC_011134.1 526511 526987 D similar to ref|NP_721985.1| methylated-DNA--protein-cysteine S-methyltransferase [Streptococcus mutans UA159]; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction:the enzyme is irreversibly inactivated.; methylated-DNA--protein-cysteine methyltransferase 526511..526987 Streptococcus equi subsp. zooepidemicus MGCS10565 6761229 YP_002122894.1 CDS Sez_0509 NC_011134.1 526991 527344 D similar to ref|YP_059682.1| Arsenate reductase family protein [Streptococcus pyogenes MGAS10394]; arsenate reductase 526991..527344 Streptococcus equi subsp. zooepidemicus MGCS10565 6761228 YP_002122895.1 CDS exoA NC_011134.1 527420 528247 R similar to ref|YP_596074.1| exodeoxyribonuclease III [Streptococcus pyogenes MGAS9429]; In addition to 3' to 5' exonuclease and 3'-phosphatase activities, exoA was shown to make single-strand breaks at apurinic sites in DNA.; exodeoxyribonuclease ExoA complement(527420..528247) Streptococcus equi subsp. zooepidemicus MGCS10565 6761209 YP_002122896.1 CDS scpC NC_011134.1 528600 533504 D similar to ref|YP_596076.1| interleukin-8 protease [Streptococcus pyogenes MGAS9429]; This virulence factor of S.pyogenes specifically cleaves IL-8.; serine endopeptidase ScpC, lactocepin, interleukin-8 protease 528600..533504 Streptococcus equi subsp. zooepidemicus MGCS10565 6761224 YP_002122897.1 CDS Sez_0512 NC_011134.1 533679 535358 D similar to ref|ZP_00874690.1| conserved hypothetical protein [Streptococcus suis 89/1591]; cell shape-determining protein 533679..535358 Streptococcus equi subsp. zooepidemicus MGCS10565 6761207 YP_002122898.1 CDS Sez_0513 NC_011134.1 535893 537077 D similar to emb|CAJ66811.1| cell-wall anchored surface adhesin [Streptococcus agalactiae]; Unknown, possible cell surface adhesin/albumin-binding protein.; cell surface protein 535893..537077 Streptococcus equi subsp. zooepidemicus MGCS10565 6761221 YP_002122899.1 CDS Sez_0514 NC_011134.1 537258 537500 D similar to ref|ZP_02010661.1| Heparinase II/III family protein [Opitutaceae bacterium TAV2]; hypothetical protein 537258..537500 Streptococcus equi subsp. zooepidemicus MGCS10565 6761210 YP_002122900.1 CDS Sez_0515 NC_011134.1 537517 538161 D similar to ref|YP_596079.1| hypothetical membrane spanning protein [Streptococcus pyogenes MGAS9429]; hypothetical protein 537517..538161 Streptococcus equi subsp. zooepidemicus MGCS10565 6761214 YP_002122901.1 CDS metG NC_011134.1 538365 540383 D methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content; methionyl-tRNA synthetase 538365..540383 Streptococcus equi subsp. zooepidemicus MGCS10565 6761200 YP_002122902.1 CDS plcR NC_011134.1 540941 541834 D similar to ref|YP_001451328.1| transcription activator plcR [Streptococcus gordonii str. Challis substr. CH1]; transcriptional regulator PlcR 540941..541834 Streptococcus equi subsp. zooepidemicus MGCS10565 6761199 YP_002122903.1 CDS Sez_0518 NC_011134.1 542187 542327 D possible competence stimulating peptide with double glycine leader peptide and ABC transporter secretion; hypothetical protein 542187..542327 Streptococcus equi subsp. zooepidemicus MGCS10565 6761205 YP_002122904.1 CDS Sez_0519 NC_011134.1 542467 542598 D possible competence stimulating peptide with double glycine leader peptide and ABC transporter secretion.; hypothetical protein 542467..542598 Streptococcus equi subsp. zooepidemicus MGCS10565 6761203 YP_002122905.1 CDS Sez_0520 NC_011134.1 542781 542948 D possible competence stimulating peptide with double glycine leader peptide and ABC transporter secretion.; hypothetical protein 542781..542948 Streptococcus equi subsp. zooepidemicus MGCS10565 6761204 YP_002122906.1 CDS comA NC_011134.1 543175 545328 D similar to ref|ZP_01824165.1| competence factor transporting ATP-binding/permease ComA [Streptococcus pneumoniae SP11-BS70]; Required for induction of competence. Seems to transport the competence-stimulating peptide (CSP).; transport/processing ATP-binding protein ComA 543175..545328 Streptococcus equi subsp. zooepidemicus MGCS10565 6761192 YP_002122907.1 CDS comB NC_011134.1 545343 546710 D similar to ref|YP_815485.1| competence factor transport protein ComB [Streptococcus pneumoniae D39]; Required for induction of competence.; transport protein ComB 545343..546710 Streptococcus equi subsp. zooepidemicus MGCS10565 6761198 YP_002122908.1 CDS Sez_0523 NC_011134.1 547291 547455 D similar to ref|ZP_00874789.1| conserved hypothetical protein [Streptococcus suis 89/1591]; hypothetical protein 547291..547455 Streptococcus equi subsp. zooepidemicus MGCS10565 6761195 YP_002122909.1 CDS nrdF NC_011134.1 547910 548923 D similar to ref|YP_601843.1| ribonucleotide-diphosphate reductase subunit beta [Streptococcus pyogenes MGAS10750]; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.; ribonucleotide-diphosphate reductase subunit beta 547910..548923 Streptococcus equi subsp. zooepidemicus MGCS10565 6761196 YP_002122910.1 CDS nrdI NC_011134.1 548925 549335 D similar to ref|YP_601844.1| ribonucleotide reductase stimulatory protein [Streptococcus pyogenes MGAS10750]; Unknown; probably involved in ribonucleotide reductase function.; ribonucleotide reduction protein NrdI 548925..549335 Streptococcus equi subsp. zooepidemicus MGCS10565 6761193 YP_002122911.1 CDS nrdE NC_011134.1 549381 551555 D Catalyzes the rate-limiting step in dNTP synthesis; ribonucleotide-diphosphate reductase subunit alpha 549381..551555 Streptococcus equi subsp. zooepidemicus MGCS10565 6761188 YP_002122912.1 CDS Sez_0527 NC_011134.1 551523 551690 R similar to ref|NP_486386.1| hypothetical protein alr2346 [Nostoc sp. PCC 7120]; hypothetical protein complement(551523..551690) Streptococcus equi subsp. zooepidemicus MGCS10565 6761185 YP_002122913.1 CDS braB NC_011134.1 552109 553452 D similar to ref|ZP_00781600.1| branched-chain amino acid transport system II carrier protein [Streptococcus agalactiae 18RS21]; Component of the transport system for branched-chain amino acids (leucine, isoleucine and valine) Which is coupled to a proton motive force.; branched-chain amino acid transport system carrier protein BraB 552109..553452 Streptococcus equi subsp. zooepidemicus MGCS10565 6761181 YP_002122914.1 CDS Sez_0529 NC_011134.1 553571 554863 R similar to ref|ZP_00875692.1| Transposase, IS204/IS1001/IS1096/IS1165 [Streptococcus suis 89/1591]; transposase IS1193D complement(553571..554863) Streptococcus equi subsp. zooepidemicus MGCS10565 6761189 YP_002122915.1 CDS esxA NC_011134.1 555369 555665 D similar to ref|ZP_02093562.1| hypothetical protein PEPMIC_00313 [Peptostreptococcus micros ATCC 33270]; Virulence factor that is important for the establishment of infection in the host. pfam06013 Proteins of 100 residues with WXG. ESAT-6 is a small protein appears to be of fundamental importance in virulence and protective immunity in Mycobacterium tuberculosis. Homologues have been detected in other Gram-positive bacterial species. It may represent a novel secretion system potentially driven by the pfam01580 domains in the YukA-like proteins.; ESAT-6/Esx family secreted protein EsxA/YukE 555369..555665 Streptococcus equi subsp. zooepidemicus MGCS10565 6761176 YP_002122916.1 CDS esaA NC_011134.1 555785 558922 D similar to ref|ZP_02093561.1| hypothetical protein PEPMIC_00312 [Peptostreptococcus micros ATCC 33270]; Unknown, likely involved in export of the adjacent ESAT-6 family protein.; secretion accessory protein EsaA/YueB 555785..558922 Streptococcus equi subsp. zooepidemicus MGCS10565 6761183 YP_002122917.1 CDS Sez_0532 NC_011134.1 558888 559412 D similar to ref|ZP_02093560.1| hypothetical protein PEPMIC_00311 [Peptostreptococcus micros ATCC 33270]; hypothetical protein 558888..559412 Streptococcus equi subsp. zooepidemicus MGCS10565 6761180 YP_002122918.1 CDS Sez_0533 NC_011134.1 559695 559973 D similar to ref|ZP_02093559.1| hypothetical protein PEPMIC_00310 [Peptostreptococcus micros ATCC 33270]; hypothetical protein 559695..559973 Streptococcus equi subsp. zooepidemicus MGCS10565 6761158 YP_002122919.1 CDS essB NC_011134.1 559976 561133 D similar to ref|ZP_02093558.1| hypothetical protein PEPMIC_00309 [Peptostreptococcus micros ATCC 33270]; Required for secretion of esxA.; secretion system component EssB/YukC 559976..561133 Streptococcus equi subsp. zooepidemicus MGCS10565 6761179 YP_002122920.1 CDS essC NC_011134.1 561145 565521 D similar to ref|ZP_02093557.1| hypothetical protein PEPMIC_00308 [Peptostreptococcus micros ATCC 33270]; Possibly involved in export of the adjacent ESAT-6 family protein.; DNA translocase FtsK 561145..565521 Streptococcus equi subsp. zooepidemicus MGCS10565 6761174 YP_002122921.1 CDS Sez_0536 NC_011134.1 565534 565863 D similar to ref|ZP_02093556.1| hypothetical protein PEPMIC_00307 [Peptostreptococcus micros ATCC 33270]; hypothetical protein 565534..565863 Streptococcus equi subsp. zooepidemicus MGCS10565 6761066 YP_002122922.1 CDS Sez_0537 NC_011134.1 565867 566301 D similar to ref|ZP_02093555.1| hypothetical protein PEPMIC_00306 [Peptostreptococcus micros ATCC 33270]; hypothetical protein 565867..566301 Streptococcus equi subsp. zooepidemicus MGCS10565 6761170 YP_002122923.1 CDS Sez_0538 NC_011134.1 566303 566587 D similar to ref|ZP_02093554.1| hypothetical protein PEPMIC_00305 [Peptostreptococcus micros ATCC 33270]; hypothetical protein 566303..566587 Streptococcus equi subsp. zooepidemicus MGCS10565 6761169 YP_002122924.1 CDS Sez_0539 NC_011134.1 566699 568519 D similar to ref|ZP_02093553.1| hypothetical protein PEPMIC_00304 [Peptostreptococcus micros ATCC 33270]; hypothetical protein 566699..568519 Streptococcus equi subsp. zooepidemicus MGCS10565 6761168 YP_002122925.1 CDS Sez_0540 NC_011134.1 568501 568890 D similar to ref|YP_001450781.1| Gene info hypothetical protein SGO_1502 [Streptococcus gordonii str. Challis substr. CH1]; hypothetical protein 568501..568890 Streptococcus equi subsp. zooepidemicus MGCS10565 6761166 YP_002122926.1 CDS Sez_0541 NC_011134.1 568915 569322 D similar to ref|ZP_00230000.1| hypothetical protein LMOh7858_0095 [Listeria monocytogenes str. 4b H7858]; hypothetical protein 568915..569322 Streptococcus equi subsp. zooepidemicus MGCS10565 6761163 YP_002122927.1 CDS Sez_0542 NC_011134.1 569392 570507 D similar to ref|ZP_02093564.1| hypothetical protein PEPMIC_00315 [Peptostreptococcus micros ATCC 33270]; hypothetical protein 569392..570507 Streptococcus equi subsp. zooepidemicus MGCS10565 6761146 YP_002122928.1 CDS Sez_0543 NC_011134.1 570504 570803 D similar to ref|YP_983629.1| Gene info UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase [Polaromonas naphthalenivorans CJ2]; hypothetical protein 570504..570803 Streptococcus equi subsp. zooepidemicus MGCS10565 6761149 YP_002122929.1 CDS Sez_0544 NC_011134.1 570968 571297 D similar to ref|NP_928651.1| hypothetical protein plu1347 [Photorhabdus luminescens subsp. laumondii TTO1]; hypothetical protein 570968..571297 Streptococcus equi subsp. zooepidemicus MGCS10565 6761162 YP_002122930.1 CDS Sez_0545 NC_011134.1 571313 571579 D similar to ref|XP_001092846.1| PREDICTED: immunoglobulin lambda variable 7-43 [Macaca mulatta]; hypothetical protein 571313..571579 Streptococcus equi subsp. zooepidemicus MGCS10565 6761136 YP_002122931.1 CDS Sez_0546 NC_011134.1 571656 572027 D similar to ref|ZP_01090397.1| hypothetical protein DSM3645_11836 [Blastopirellula marina DSM 3645]; hypothetical protein 571656..572027 Streptococcus equi subsp. zooepidemicus MGCS10565 6761155 YP_002122932.1 CDS Sez_0547 NC_011134.1 572028 572621 D similar to ref|YP_001093031.1| Transketolase, central region [Shewanella loihica PV-4]; hypothetical protein 572028..572621 Streptococcus equi subsp. zooepidemicus MGCS10565 6761156 YP_002122933.1 CDS cas3 NC_011134.1 573087 575540 D similar to ref|NP_722087.1| hypothetical protein SMU.1764c [Streptococcus mutans UA159]; CRISPR mediated immunity, TIGRFAM TIGR01596.; CRISPR-Associated Helicase Cas3 Core 573087..575540 Streptococcus equi subsp. zooepidemicus MGCS10565 6761135 YP_002122934.1 CDS cas5 NC_011134.1 575781 576500 D similar to ref|NP_722086.1| hypothetical protein SMU.1763c [Streptococcus mutans UA159]; CRISPR mediated immunity, TIGRFAM TIGR01876.; CRISPR-associated protein Cas5 575781..576500 Streptococcus equi subsp. zooepidemicus MGCS10565 6761153 YP_002122935.1 CDS csd1 NC_011134.1 576500 578383 D similar to ref|YP_598979.1| hypothetical protein MGAS10270_Spy1370 [Streptococcus pyogenes MGAS10270]; CRISPR mediated immunity, TIGRFAM TIGR01863.; Csd1 family CRISPR-associated protein 576500..578383 Streptococcus equi subsp. zooepidemicus MGCS10565 6761150 YP_002122936.1 CDS csd2 NC_011134.1 578384 579232 D similar to ref|YP_280757.1| hypothetical cytosolic protein [Streptococcus pyogenes MGAS6180]; CRISPR mediated immunity, TIGRFAM TIGR02589.; Csd2 family CRISPR-associated protein 578384..579232 Streptococcus equi subsp. zooepidemicus MGCS10565 6761147 YP_002122937.1 CDS cas4 NC_011134.1 579234 579905 D similar to ref|NP_269629.1| hypothetical protein SPy_1563 [Streptococcus pyogenes M1 GAS]; CRISPR mediated immunity, TIGRFAM TIGR00372.; CRISPR-associated RecB family exonuclease Cas4b 579234..579905 Streptococcus equi subsp. zooepidemicus MGCS10565 6761143 YP_002122938.1 CDS cas1 NC_011134.1 579902 580927 D similar to ref|YP_597011.1| hypothetical protein MGAS9429_Spy1280 [Streptococcus pyogenes MGAS9429]; CRISPR mediated immunity, TIGRFAM TIGR00287.; CRISPR-associated protein Cas1 579902..580927 Streptococcus equi subsp. zooepidemicus MGCS10565 6761138 YP_002122939.1 CDS cas2 NC_011134.1 580938 581231 D similar to ref|NP_722078.1| hypothetical protein SMU.1753c [Streptococcus mutans UA159]; CRISPR mediated immunity, TIGRFAM TIGR01573.; CRISPR-associated protein Cas2 580938..581231 Streptococcus equi subsp. zooepidemicus MGCS10565 6761137 YP_002122940.1 CDS dsbD NC_011134.1 584155 584865 D similar to ref|YP_001128141.1| cytochrome c-type biogenesis protein [Streptococcus pyogenes str. Manfredo]; Could be involved in cytochrome c synthesis.; cytochrome c-type biogenesis protein CcdA (DsbD analog) 584155..584865 Streptococcus equi subsp. zooepidemicus MGCS10565 6761141 YP_002122941.1 CDS dsbE NC_011134.1 584858 585529 D similar to gb|AAN18289.1| lipoprotein [Streptococcus equi]; Involved in disulfide bond formation; related to ResA; thiol:disulfide oxidoreductase 584858..585529 Streptococcus equi subsp. zooepidemicus MGCS10565 6761124 YP_002122942.1 CDS msrAB NC_011134.1 585547 586659 D similar to ref|NP_269624.1| bifunctional methionine sulfoxide reductase A/B protein [Streptococcus pyogenes M1 GAS]; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.; peptide methionine sulfoxide reductase 585547..586659 Streptococcus equi subsp. zooepidemicus MGCS10565 6761102 YP_002122943.1 CDS yesN NC_011134.1 586832 587668 D similar to gb|AAN18291.1| two-component response regulator [Streptococcus equi]; two-component response regulator YesN-like 586832..587668 Streptococcus equi subsp. zooepidemicus MGCS10565 6761050 YP_002122944.1 CDS yesM NC_011134.1 587665 589383 D similar to ref|YP_282643.1| two-component sensor kinase [Streptococcus pyogenes MGAS5005]; two-component sensor kinase YesM-like 587665..589383 Streptococcus equi subsp. zooepidemicus MGCS10565 6761116 YP_002122945.1 CDS Sez_0563 NC_011134.1 589423 590511 D similar to ref|YP_602880.1| hypothetical cytosolic protein [Streptococcus pyogenes MGAS10750]; hypothetical protein 589423..590511 Streptococcus equi subsp. zooepidemicus MGCS10565 6761131 YP_002122946.1 CDS Sez_0564 NC_011134.1 590526 591230 D similar to ref|YP_598902.1| hypothetical protein MGAS10270_Spy1293 [Streptococcus pyogenes MGAS10270]; hypothetical protein 590526..591230 Streptococcus equi subsp. zooepidemicus MGCS10565 6761111 YP_002122947.1 CDS Sez_0565 NC_011134.1 591465 591977 D similar to ref|YP_619784.1| hypothetical protein Ldb2202 [Lactobacillus delbrueckii subsp. bulgaricus ATCC 11842]; hypothetical protein 591465..591977 Streptococcus equi subsp. zooepidemicus MGCS10565 6761127 YP_002122948.1 CDS argR NC_011134.1 592488 592961 R similar to ref|YP_598901.1| Arginine repressor, argR [Streptococcus pyogenes MGAS10270]; Regulates arginine biosynthesis genes.; arginine repressor ArgR complement(592488..592961) Streptococcus equi subsp. zooepidemicus MGCS10565 6761120 YP_002122949.1 CDS arcR NC_011134.1 593102 593782 D similar to dbj|BAE46419.1| CRP/FNR transcriptional regulator [Streptococcus equi subsp. zooepidemicus]; ArcR family transcriptional regulator 593102..593782 Streptococcus equi subsp. zooepidemicus MGCS10565 6761096 YP_002122950.1 CDS arcA NC_011134.1 594051 595286 D catalyzes the degradation of arginine to citruline and ammonia; arginine deiminase 594051..595286 Streptococcus equi subsp. zooepidemicus MGCS10565 6761100 YP_002122951.1 CDS Sez_0569 NC_011134.1 595296 595727 D similar to dbj|BAE46421.1| GNAT family acetyltransferase [Streptococcus equi subsp. zooepidemicus]; GNAT family acetyltransferase 595296..595727 Streptococcus equi subsp. zooepidemicus MGCS10565 6761113 YP_002122952.1 CDS arcB NC_011134.1 595742 596755 D catalyzes the formation of ornithine and carbamylphosphate from citrulline in the arginine catabolic pathway; ornithine carbamoyltransferase 595742..596755 Streptococcus equi subsp. zooepidemicus MGCS10565 6761107 YP_002122953.1 CDS arcD NC_011134.1 596917 598410 D similar to dbj|BAE46423.1| arginine/ornithine antiporter [Streptococcus equi subsp. zooepidemicus]; arginine/ornithine antiporter ArcD 596917..598410 Streptococcus equi subsp. zooepidemicus MGCS10565 6761106 YP_002122954.1 CDS Sez_0572 NC_011134.1 598427 599758 D similar to ref|ZP_00365692.1| COG0624: Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases [Streptococcus pyogenes M49 591]; catalyzing the hydrolysis of N2-acetyl-l-ornithine to l-ornithine and acetate.; hypothetical protein 598427..599758 Streptococcus equi subsp. zooepidemicus MGCS10565 6761074 YP_002122955.1 CDS arcC NC_011134.1 599776 600726 D catalyzes the reversible synthesis of carbamate and ATP from carbamoyl phosphate and ADP; carbamate kinase 599776..600726 Streptococcus equi subsp. zooepidemicus MGCS10565 6761110 YP_002122956.1 CDS asnA NC_011134.1 600945 601937 D catalyzes the formation of asparagine from aspartate and ammonia; asparagine synthetase AsnA 600945..601937 Streptococcus equi subsp. zooepidemicus MGCS10565 6761101 YP_002122957.1 CDS Sez_0575 NC_011134.1 602106 602645 D similar to ref|ZP_00365420.1| COG0742: N6-adenine-specific methylase [Streptococcus pyogenes M49 591]; Methyltransferase; methylase 602106..602645 Streptococcus equi subsp. zooepidemicus MGCS10565 6761086 YP_002122958.1 CDS coaD NC_011134.1 602635 603135 D Catalyzes the conversion of ATP and pantetheine 4'-phosphate to diphosphate and 3'-dephospho-coA; phosphopantetheine adenylyltransferase 602635..603135 Streptococcus equi subsp. zooepidemicus MGCS10565 6761098 YP_002122959.1 CDS Sez_0577 NC_011134.1 603113 604150 D similar to ref|YP_060605.1| ATP-dependent protease La [Streptococcus pyogenes MGAS10394]; Lon-like protease with PDZ domain 603113..604150 Streptococcus equi subsp. zooepidemicus MGCS10565 6761064 YP_002122960.1 CDS Sez_0578 NC_011134.1 604726 605370 D similar to ref|YP_060601.1| Transcriptional regulator [Streptococcus pyogenes MGAS10394]; transcriptional regulator 604726..605370 Streptococcus equi subsp. zooepidemicus MGCS10565 6761084 YP_002122961.1 CDS Sez_0579 NC_011134.1 605374 606456 D 23S rRNA m2A2503 methyltransferase; methylates the C2 position of the A2530 nucleotide in 23S rRNA; may be involved in antibiotic resistance; ribosomal RNA large subunit methyltransferase N 605374..606456 Streptococcus equi subsp. zooepidemicus MGCS10565 6761088 YP_002122962.1 CDS Sez_0580 NC_011134.1 607020 607925 D similar to ref|YP_001451006.1| ABC transporter ATP-binding protein SP2003 [Streptococcus gordonii str. Challis substr. CH1]; multi drug transpot ATP-binding protein 607020..607925 Streptococcus equi subsp. zooepidemicus MGCS10565 6761081 YP_002122963.1 CDS Sez_0581 NC_011134.1 607929 608654 D similar to ref|NP_687344.1| ABC transporter, permease, [Streptococcus agalactiae 2603V/R]; ABC transporter permease 607929..608654 Streptococcus equi subsp. zooepidemicus MGCS10565 6761076 YP_002122964.1 CDS Sez_0582 NC_011134.1 608654 609766 D similar to ref|YP_139771.1| sensor histidine kinase (homolog to HK11 Spn) [Streptococcus thermophilus LMG 18311]; TCS sensor histidine kinase 608654..609766 Streptococcus equi subsp. zooepidemicus MGCS10565 6761092 YP_002122965.1 CDS Sez_0583 NC_011134.1 609747 610343 D similar to ref|ZP_00784861.1| response regulator [Streptococcus agalactiae COH1]; TCS response regulator 609747..610343 Streptococcus equi subsp. zooepidemicus MGCS10565 6761068 YP_002122966.1 CDS pilD NC_011134.1 610404 611045 R similar to ref|YP_598885.1| Type 4 prepilin peptidase pilD [Streptococcus pyogenes MGAS10270]; type IV prepilin peptidase PilD / late competence protein ComC processing protease complement(610404..611045) Streptococcus equi subsp. zooepidemicus MGCS10565 6761078 YP_002122967.1 CDS dpr NC_011134.1 611253 611783 D similar to ref|NP_269604.1| peroxide resistance protein [Streptococcus pyogenes M1 GAS]; Is involved in iron storage. May also be involved in the metabolic response to stress conditions.; DNA binding protein starved cells-like peroxide resistance protein Dpr 611253..611783 Streptococcus equi subsp. zooepidemicus MGCS10565 6761077 YP_002122968.1 CDS Sez_0586 NC_011134.1 612153 612386 D similar to ref|NP_664985.1| hypothetical protein SpyM3_1181 [Streptococcus pyogenes MGAS315]; hypothetical protein 612153..612386 Streptococcus equi subsp. zooepidemicus MGCS10565 6761048 YP_002122969.1 CDS glcK NC_011134.1 612361 613332 D similar to ref|NP_607614.1| glucose kinase [Streptococcus pyogenes MGAS8232]; Catalysis of the reaction: ATP + D-glucose = ADP + D-glucose 6-phosphate.; glucokinase 612361..613332 Streptococcus equi subsp. zooepidemicus MGCS10565 6761061 YP_002122970.1 CDS Sez_0588 NC_011134.1 613357 613722 D similar to ref|YP_060595.1| Rhodanese-related sulfurtransferase [Streptococcus pyogenes MGAS10394]; rhodanese-Like domain-containing protein 613357..613722 Streptococcus equi subsp. zooepidemicus MGCS10565 6761041 YP_002122971.1 CDS typA NC_011134.1 614100 615959 D similar to ref|NP_269600.1| GTP-binding protein TypA/BipA (tyrosine phosphorylated protein A) [Streptococcus pyogenes M1 GAS]; Unknown; probably interacts with the ribosomes in a GTP dependent manner.; GTP-binding protein TypA 614100..615959 Streptococcus equi subsp. zooepidemicus MGCS10565 6761042 YP_002122972.1 CDS Sez_0590 NC_011134.1 616044 616292 D similar to ref|NP_607611.1| hypothetical protein spyM18_1543 [Streptococcus pyogenes MGAS8232]; hypothetical protein 616044..616292 Streptococcus equi subsp. zooepidemicus MGCS10565 6761062 YP_002122973.1 CDS murD NC_011134.1 616445 617803 D UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase 616445..617803 Streptococcus equi subsp. zooepidemicus MGCS10565 6761058 YP_002122974.1 CDS murG NC_011134.1 617803 618885 D UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; involved in cell wall formation; inner membrane-associated; last step of peptidoglycan synthesis; UDP diphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase 617803..618885 Streptococcus equi subsp. zooepidemicus MGCS10565 6761056 YP_002122975.1 CDS ftsQ NC_011134.1 618886 620076 D similar to ref|NP_269596.1| cell division protein [Streptococcus pyogenes M1 GAS]; Required for the initiation of cell division. Exact function not known.; cell division protein FtsQ 618886..620076 Streptococcus equi subsp. zooepidemicus MGCS10565 6761059 YP_002122976.1 CDS ftsA NC_011134.1 620288 621652 D similar to ref|YP_060589.1| Cell division protein ftsA [Streptococcus pyogenes MGAS10394]; This protein may be involved in anomalous filament growth. May be a component of the septum. It may interact with ftsZ (By similarity).; cell division protein FtsA 620288..621652 Streptococcus equi subsp. zooepidemicus MGCS10565 6761057 YP_002122977.1 CDS Sez_0597 NC_011134.1 623005 623679 D similar to ref|YP_280652.1| pyridoxal-5'-phosphate family protein [Streptococcus pyogenes MGAS6180]; pyridoxaL 5'-phosphate dependent enzyme class III family 623005..623679 Streptococcus equi subsp. zooepidemicus MGCS10565 6761051 YP_002122978.1 CDS Sez_0598 NC_011134.1 623680 624354 D similar to ref|ZP_00366475.1| COG1799: Uncharacterized protein conserved in bacteria [Streptococcus pyogenes M49 591]; hypothetical protein 623680..624354 Streptococcus equi subsp. zooepidemicus MGCS10565 6761047 YP_002122979.1 CDS Sez_0599 NC_011134.1 624410 624616 D similar to ref|ZP_00366474.1| COG0762: Predicted integral membrane protein [Streptococcus pyogenes M49 591]; hypothetical protein 624410..624616 Streptococcus equi subsp. zooepidemicus MGCS10565 6761044 YP_002122980.1 CDS Sez_0600 NC_011134.1 624613 625224 D similar to ref|YP_060584.1| RNA binding protein [Streptococcus pyogenes MGAS10394]; Unknown, The S4 domain is a small domain consisting of 60-65 amino acid residues that was detected in the bacterial ribosomal protein S4, eukaryotic ribosomal S9, two families of pseudouridine synthases, a novel family of predicted RNA methylases, a yeast protein containing a pseudouridine synthetase and a deaminase domain, bacterial tyrosyl-tRNA synthetases, and a number of uncharacterized, small proteins that may be involved in translation regulation. The S4 domain probably mediates binding to RNA.; S4 domain-containing protein 624613..625224 Streptococcus equi subsp. zooepidemicus MGCS10565 6761029 YP_002122981.1 CDS divIVA NC_011134.1 625416 626171 D similar to ref|YP_280648.1| cell division initiation protein DivIVA [Streptococcus pyogenes MGAS6180]; cell division initiation protein DivIVA 625416..626171 Streptococcus equi subsp. zooepidemicus MGCS10565 6761037 YP_002122982.1 CDS ileS NC_011134.1 626443 629241 D IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase family; some organisms carry two different copies of this enzyme; isoleucyl-tRNA synthetase 626443..629241 Streptococcus equi subsp. zooepidemicus MGCS10565 6761036 YP_002122983.1 CDS Sez_0603 NC_011134.1 629710 630012 R similar to ref|NP_607599.1| hypothetical protein spyM18_1529 [Streptococcus pyogenes MGAS8232]; hypothetical protein complement(629710..630012) Streptococcus equi subsp. zooepidemicus MGCS10565 6761035 YP_002122984.1 CDS mutT NC_011134.1 630074 630520 R similar to ref|YP_280645.1| mutator protein (7,8-dihydro-8-oxoguanine-triphosphatase) [Streptococcus pyogenes MGAS6180]; Specific for pyrimidine substrates. Acts on 5-methyl- dCTP, CTP and dCTP in decreasing order.; MutT/nudix family protein complement(630074..630520) Streptococcus equi subsp. zooepidemicus MGCS10565 6760994 YP_002122985.1 CDS clpE NC_011134.1 630667 632919 R similar to ref|YP_596966.1| ATP-dependent endopeptidase clp ATP-binding subunit [Streptococcus pyogenes MGAS9429]; Could be necessary for degrading proteins generated by certain types of stress.; ATP-dependent Clp protease ATP-binding subunit ClpE complement(630667..632919) Streptococcus equi subsp. zooepidemicus MGCS10565 6761032 YP_002122986.1 CDS Sez_0606 NC_011134.1 633202 633432 D similar to ref|NP_269584.1| hypothetical protein SPy_1508 [Streptococcus pyogenes M1 GAS]; hypothetical protein 633202..633432 Streptococcus equi subsp. zooepidemicus MGCS10565 6761020 YP_002122987.1 CDS Sez_0607 NC_011134.1 633440 633568 D similar to ref|NP_730978.1| sec23 CG1250-PA, isoform A [Drosophila melanogaster]; hypothetical protein 633440..633568 Streptococcus equi subsp. zooepidemicus MGCS10565 6761028 YP_002122988.1 CDS sclZ.7 NC_011134.1 633877 635202 R similar to gb|ABA41499.1| collagen-like protein I [Streptococcus equi subsp. equi]; Possible adhesin, has a collagen-structural-motif domain composed of 95 Gly-Xaa-Yaa repeats.; hypothetical protein complement(633877..635202) Streptococcus equi subsp. zooepidemicus MGCS10565 6761026 YP_002122989.1 CDS Sez_0609 NC_011134.1 635548 636027 D similar to ref|YP_280642.1| arginine transport system permease [Streptococcus pyogenes MGAS6180]; Probably part of a binding-protein-dependent transport system for an amino acid. Probably responsible for the translocation of the substrate across the membrane.; glutamine ABC transporter permease 635548..636027 Streptococcus equi subsp. zooepidemicus MGCS10565 6761001 YP_002122990.1 CDS glnP NC_011134.1 636077 636232 D similar to ref|NP_607595.1| amino acid ABC transporter (permease) [Streptococcus pyogenes MGAS8232]; Part Of The Binding-Protein-Dependent Transport System For Glutamine; Probably Responsible For The Translocation Of The Substrate Across The Membrane.; glutamine amino acid ABC transporter GlnP 636077..636232 Streptococcus equi subsp. zooepidemicus MGCS10565 6761022 YP_002122991.1 CDS Sez_0611 NC_011134.1 636234 636971 D similar to ref|NP_721003.1| amino acid ABC transporter, ATP-binding protein [Streptococcus mutans UA159]; Probably part of a binding-protein-dependent transport system for an amino acid. Probably responsible for energy coupling to the transport system.; glutamine amino-acid ABC transporter ATP-binding protein 636234..636971 Streptococcus equi subsp. zooepidemicus MGCS10565 6761023 YP_002122992.1 CDS Sez_0612 NC_011134.1 637097 637222 D hypothetical protein 637097..637222 Streptococcus equi subsp. zooepidemicus MGCS10565 6761021 YP_002122993.1 CDS Sez_0613 NC_011134.1 637418 639112 D similar to ref|ZP_00790189.1| phosphoglucomutase/phosphomannomutase family protein [Streptococcus agalactiae 515]; May be involved in the production of an extracellular matrix that lends structure to the pellicle of biofilms. Through its possible activity of phosphoexomutase, it may promote the synthesis of nucleotide sugars, which are incorporated into exopolysaccharides of the extracelllular matrix of B.subtilis communities.; phosphomannomutase 637418..639112 Streptococcus equi subsp. zooepidemicus MGCS10565 6761019 YP_002122994.1 CDS folD NC_011134.1 639224 640078 D catalyzes the formation of 5,10-methenyltetrahydrofolate from 5,10-methylenetetrahydrofolate and subsequent formation of 10-formyltetrahydrofolate from 5,10-methenyltetrahydrofolate; bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase 639224..640078 Streptococcus equi subsp. zooepidemicus MGCS10565 6761018 YP_002122995.1 CDS Sez_0615 NC_011134.1 640075 640929 D similar to ref|YP_139133.1| hypothetical protein stu0612 [Streptococcus thermophilus LMG 18311]; sugar kinase 640075..640929 Streptococcus equi subsp. zooepidemicus MGCS10565 6761017 YP_002122996.1 CDS Sez_0616 NC_011134.1 640926 641051 D hypothetical protein 640926..641051 Streptococcus equi subsp. zooepidemicus MGCS10565 6761015 YP_002122997.1 CDS xseA NC_011134.1 641213 642553 D bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides; exodeoxyribonuclease VII large subunit 641213..642553 Streptococcus equi subsp. zooepidemicus MGCS10565 6761016 YP_002122998.1 CDS xseB NC_011134.1 642531 642746 D catalyzes the bidirectional exonucleolytic cleavage of DNA; exodeoxyribonuclease VII small subunit 642531..642746 Streptococcus equi subsp. zooepidemicus MGCS10565 6761014 YP_002122999.1 CDS lepA NC_011134.1 642746 643615 D similar to ref|NP_607588.1| geranyltranstransferase [Streptococcus pyogenes MGAS8232]; geranyltranstransferase 642746..643615 Streptococcus equi subsp. zooepidemicus MGCS10565 6761007 YP_002123000.1 CDS Sez_0620 NC_011134.1 643608 644435 D similar to ref|NP_664957.1| hemolysin [Streptococcus pyogenes MGAS315]; hemolysin A 643608..644435 Streptococcus equi subsp. zooepidemicus MGCS10565 6761012 YP_002123001.1 CDS argR NC_011134.1 644458 644892 D similar to ref|YP_598854.1| Arginine repressor, argR [Streptococcus pyogenes MGAS10270]; Regulates arginine biosynthesis genes.; arginine repressor ArgR 644458..644892 Streptococcus equi subsp. zooepidemicus MGCS10565 6761013 YP_002123002.1 CDS recN NC_011134.1 644871 646571 D similar to ref|YP_600842.1| DNA repair protein recN [Streptococcus pyogenes MGAS2096]; May be involved in recombinational repair of damaged DNA.; DNA repair protein RecN 644871..646571 Streptococcus equi subsp. zooepidemicus MGCS10565 6761004 YP_002123003.1 CDS Sez_0623 NC_011134.1 646791 647663 D similar to ref|YP_602827.1| hypothetical protein MGAS10750_Spy1333 [Streptococcus pyogenes MGAS10750]; hypothetical protein 646791..647663 Streptococcus equi subsp. zooepidemicus MGCS10565 6761011 YP_002123004.1 CDS Sez_0624 NC_011134.1 647801 648652 D similar to ref|YP_598851.1| Fatty acid-binding protein, DegV family [Streptococcus pyogenes MGAS10270]; DegV family protein 647801..648652 Streptococcus equi subsp. zooepidemicus MGCS10565 6761010 YP_002123005.1 CDS Sez_0625 NC_011134.1 648645 649487 D similar to ref|YP_282588.1| lipase/acylhydrolase with GDSL-like motif [Streptococcus pyogenes MGAS5005]; lipase/acylhydrolase with GDSL-like motif 648645..649487 Streptococcus equi subsp. zooepidemicus MGCS10565 6761009 YP_002123006.1 CDS Sez_0626 NC_011134.1 649465 650052 D similar to ref|YP_280628.1| hypothetical membrane associated protein [Streptococcus pyogenes MGAS6180]; hypothetical protein 649465..650052 Streptococcus equi subsp. zooepidemicus MGCS10565 6760999 YP_002123007.1 CDS hup NC_011134.1 650150 650425 D similar to ref|NP_664950.1| histone-like DNA-binding protein [Streptococcus pyogenes MGAS315]; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. Seems also to act as a fortuitous virulence factor in delayed sequelae by binding to heparan sulfate-proteoglycans in the extracellular matrix of target organs and acting as a nidus for in situ immune complex formation.; DNA-binding protein HU 650150..650425 Streptococcus equi subsp. zooepidemicus MGCS10565 6761008 YP_002123008.1 CDS Sez_0628 NC_011134.1 650483 651187 R similar to ref|YP_597959.1| C3 family ADP-ribosyltransferase [Streptococcus pyogenes MGAS10270]; C3 family ADP-ribosyltransferase complement(650483..651187) Streptococcus equi subsp. zooepidemicus MGCS10565 6761005 YP_002123009.1 CDS Sez_0629 NC_011134.1 651498 652187 R similar to ref|YP_001450179.1| transporter, SP1116 [Streptococcus gordonii str. Challis substr. CH1]; macrolide ABC transporter permease complement(651498..652187) Streptococcus equi subsp. zooepidemicus MGCS10565 6761003 YP_002123010.1 CDS Sez_0630 NC_011134.1 652205 652705 R similar to ref|NP_734700.1| hypothetical protein gbs0231 [Streptococcus agalactiae NEM316]; hypothetical protein complement(652205..652705) Streptococcus equi subsp. zooepidemicus MGCS10565 6761000 YP_002123011.1 CDS Sez_0631 NC_011134.1 652760 653653 R similar to ref|ZP_01820549.1| transcriptional regulator MutR, [Streptococcus pneumoniae SP6-BS73]; positive transcriptional regulator MutR family complement(652760..653653) Streptococcus equi subsp. zooepidemicus MGCS10565 6760995 YP_002123012.1 CDS Sez_0632 NC_011134.1 654024 654197 D similar to ref|NP_664896.1| hypothetical protein SpyM3_1092 [Streptococcus pyogenes MGAS315]; hypothetical protein 654024..654197 Streptococcus equi subsp. zooepidemicus MGCS10565 6761002 YP_002123013.1 CDS Sez_0633 NC_011134.1 654245 655129 R catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway; subclass 1A is a dimer formed by two identical PyrD subunits each containing an FMN group; dihydroorotate dehydrogenase 1A complement(654245..655129) Streptococcus equi subsp. zooepidemicus MGCS10565 6760988 YP_002123014.1 CDS Sez_0634 NC_011134.1 655104 655367 D hypothetical protein 655104..655367 Streptococcus equi subsp. zooepidemicus MGCS10565 6760996 YP_002123015.1 CDS gpmA NC_011134.1 655424 656119 D 2,3-bisphosphoglycerate-dependent; catalyzes the interconversion of 2-phosphoglycerate to 3-phosphoglycerate; phosphoglyceromutase 655424..656119 Streptococcus equi subsp. zooepidemicus MGCS10565 6761810 YP_002123016.1 CDS Sez_0636 NC_011134.1 656207 656749 D similar to ref|YP_280622.1| transcriptional regulator, biotin repressor family [Streptococcus pyogenes MGAS6180]; transcriptional repressor 656207..656749 Streptococcus equi subsp. zooepidemicus MGCS10565 6761826 YP_002123017.1 CDS Sez_0637 NC_011134.1 656910 657098 R hypothetical protein complement(656910..657098) Streptococcus equi subsp. zooepidemicus MGCS10565 6761822 YP_002123018.1 CDS Sez_0638 NC_011134.1 657144 657683 D similar to ref|NP_269515.1| hypothetical protein SPy_1425 [Streptococcus pyogenes M1 GAS]; hypothetical protein 657144..657683 Streptococcus equi subsp. zooepidemicus MGCS10565 6761818 YP_002123019.1 CDS Sez_0639 NC_011134.1 657794 658591 D similar to ref|YP_596939.1| formate transporter [Streptococcus pyogenes MGAS9429]; Involved in the bidirectional transport of formate.; formate transporter 657794..658591 Streptococcus equi subsp. zooepidemicus MGCS10565 6761817 YP_002123020.1 CDS Sez_0640 NC_011134.1 658703 660757 D similar to ref|YP_820120.1| Cell division protein FtsI/penicillin-binding protein 2 [Streptococcus thermophilus LMD-9]; Cell Wall Formation; Pbp-2 Is Responsible For The Determination Of The Rod Shape Of The Cell. Its Synthesize Cross- Linked Peptidoglycan From The Lipid Intermediates.; cell division protein FtsI 658703..660757 Streptococcus equi subsp. zooepidemicus MGCS10565 6761815 YP_002123021.1 CDS recR NC_011134.1 660769 661365 D involved in a recombinational process of DNA repair, independent of the recBC complex; recombination protein RecR 660769..661365 Streptococcus equi subsp. zooepidemicus MGCS10565 6761794 YP_002123022.1 CDS ddl NC_011134.1 661706 662752 D D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli; D-alanyl-alanine synthetase A 661706..662752 Streptococcus equi subsp. zooepidemicus MGCS10565 6761808 YP_002123023.1 CDS murF NC_011134.1 663012 664376 D similar to ref|YP_598837.1| UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [Streptococcus pyogenes MGAS10270]; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.; UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase MurF 663012..664376 Streptococcus equi subsp. zooepidemicus MGCS10565 6761805 YP_002123024.1 CDS Sez_0644 NC_011134.1 664454 665155 D similar to ref|NP_802044.1| hypothetical protein SPs0782 [Streptococcus pyogenes SSI-1]; hypothetical protein 664454..665155 Streptococcus equi subsp. zooepidemicus MGCS10565 6761803 YP_002123025.1 CDS prfC NC_011134.1 665324 666868 D stimulates the release of release factors 1 and 2 from the ribosome after hydrolysis of the ester bond in peptidyl-tRNA has occurred; GDP/GTP-binding protein; peptide chain release factor 3 665324..666868 Streptococcus equi subsp. zooepidemicus MGCS10565 6761801 YP_002123026.1 CDS exp9 NC_011134.1 667284 668900 D similar to ref|NP_269508.1| ATP-dependent RNA helicase [Streptococcus pyogenes M1 GAS]; Has A Helix-Destabilizing Activity. Plays A Key Role In Optimal Cell Growth At Low Temperature And Is Required For Normal Cell Division. Suppressor Of A Mutant Defective In Rpsb Gene For Ribosomal Protein S2.; ATP-dependent RNA helicase Exp9 667284..668900 Streptococcus equi subsp. zooepidemicus MGCS10565 6761799 YP_002123027.1 CDS kup NC_011134.1 669026 671029 D similar to ref|YP_060497.1| Kup system potassium uptake protein [Streptococcus pyogenes MGAS10394]; Transport of potassium into the cell.; potassium transport protein Kup 669026..671029 Streptococcus equi subsp. zooepidemicus MGCS10565 6761798 YP_002123028.1 CDS Sez_0648 NC_011134.1 671249 671530 R similar to ref|YP_598831.1| hypothetical protein with endo/excinuclease domain [Streptococcus pyogenes MGAS10270]; endonuclease containing a URI domain complement(671249..671530) Streptococcus equi subsp. zooepidemicus MGCS10565 6761767 YP_002123029.1 CDS Sez_0649 NC_011134.1 671563 672330 R similar to ref|YP_280610.1| methyltransferase [Streptococcus pyogenes MGAS6180]; methyltransferase complement(671563..672330) Streptococcus equi subsp. zooepidemicus MGCS10565 6761790 YP_002123030.1 CDS Sez_0650 NC_011134.1 672415 673188 D similar to ref|YP_598829.1| 1-acyl-sn-glycerol-3-phosphate acyltransferase [Streptococcus pyogenes MGAS10270]; Catalysis of the reaction: acyl-CoA + 1-acyl-sn-glycerol 3-phosphate = CoA + 1,2-diacyl-sn-glycerol 3-phosphate.; 1-acyl-Sn-glycerol-3-phosphate acyltransferase 672415..673188 Streptococcus equi subsp. zooepidemicus MGCS10565 6761749 YP_002123031.1 CDS comEA NC_011134.1 673504 674181 D similar to ref|YP_280608.1| ComE operon protein 1 [Streptococcus pyogenes MGAS6180]; Needed for both DNA binding and transport. It is absolutely required for the uptake of transforming DNA but not for binding. Its role in binding may be indirect.; DNA receptor late competence protein ComEA 673504..674181 Streptococcus equi subsp. zooepidemicus MGCS10565 6761719 YP_002123032.1 CDS comEC NC_011134.1 674162 676405 D similar to ref|YP_001128281.1| competence protein [Streptococcus pyogenes str. Manfredo]; The comE operon is required for the binding and uptake of transforming DNA. ComEC is required for internalization but is dispensable for DNA binding.; DNA transport late competence protein ComEC 674162..676405 Streptococcus equi subsp. zooepidemicus MGCS10565 6761788 YP_002123033.1 CDS holA NC_011134.1 676518 677579 D required for the assembly and function of the DNAX complex which is required for the assembly of the beta subunit onto primed DNA; DNA polymerase III subunit delta 676518..677579 Streptococcus equi subsp. zooepidemicus MGCS10565 6761787 YP_002123034.1 CDS sodA NC_011134.1 677657 678262 D similar to ref|NP_802054.1| superoxide dismutase (Fe/Mn) [Streptococcus pyogenes SSI-1]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems.; superoxide dismutase [Mn] SodA 677657..678262 Streptococcus equi subsp. zooepidemicus MGCS10565 6761783 YP_002123035.1 CDS Sez_0655 NC_011134.1 678513 679730 R similar to ref|YP_282504.1| hypothetical cytosolic protein [Streptococcus pyogenes MGAS5005]; hypothetical protein complement(678513..679730) Streptococcus equi subsp. zooepidemicus MGCS10565 6761782 YP_002123036.1 CDS nagB NC_011134.1 681033 681737 D similar to ref|YP_060432.1| Glucosamine-6-phosphate isomerase [Streptococcus pyogenes MGAS10394]; Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.; glucosamine-6-phosphate deaminase 681033..681737 Streptococcus equi subsp. zooepidemicus MGCS10565 6761775 YP_002123037.1 CDS rsuA NC_011134.1 681909 682625 D similar to ref|YP_598817.1| Ribosomal small subunit pseudouridine synthase A [Streptococcus pyogenes MGAS10270]; Responsible for synthesis of pseudouridine from uracil- 516 in 16S ribosomal RNA.; ribosomal small subunit pseudouridine synthase A RsuA 681909..682625 Streptococcus equi subsp. zooepidemicus MGCS10565 6761773 YP_002123038.1 CDS coiA NC_011134.1 682717 683694 D similar to ref|YP_282500.1| competence protein/transcription factor [Streptococcus pyogenes MGAS5005]; competence protein/transcription factor CoiA 682717..683694 Streptococcus equi subsp. zooepidemicus MGCS10565 6761765 YP_002123039.1 CDS pepF NC_011134.1 683684 685486 D similar to ref|YP_060429.1| Oligoendopeptidase F [Streptococcus pyogenes MGAS10394]; Has oligopeptidase activity and degrades a variety of small bioactive peptides, including bradykinin, neurotensin, and peptide fragments of substance P and adrenocorticotropin. Also hydrolyzes the synthetic collagen-like substrate N-(3-[2- furyl]acryloyl)-Leu-Gly-Pro-Ala (FALGPA).; oligoendopeptidase PepF 683684..685486 Streptococcus equi subsp. zooepidemicus MGCS10565 6761763 YP_002123040.1 CDS Sez_0662 NC_011134.1 685656 686213 D similar to ref|YP_001032265.1| acetyltransferase, GNAT family [Lactococcus lactis subsp. cremoris MG1363]; GNAT family acetyltransferase 685656..686213 Streptococcus equi subsp. zooepidemicus MGCS10565 6761760 YP_002123041.1 CDS Sez_0663 NC_011134.1 686203 686835 D similar to ref|ZP_00786299.1| hydrolase, haloacid dehalogenase-like family [Streptococcus agalactiae COH1]; haloacid dehalogenase-like family hydrolase 686203..686835 Streptococcus equi subsp. zooepidemicus MGCS10565 6761757 YP_002123042.1 CDS Sez_0664 NC_011134.1 686883 687524 D similar to ref|ZP_00784655.1| hydrolase, haloacid dehalogenase-like family [Streptococcus agalactiae COH1]; Displays high phosphatase activity toward erythrose 4- phosphate, fructose 6-phosphate, 2-deoxyglucose 6-phosphate, and mannose 6-phosphate. May have a role in the intracellular metabolism of many phosphorylated carbohydrates.; phosphoglycolate phosphatase 686883..687524 Streptococcus equi subsp. zooepidemicus MGCS10565 6761754 YP_002123043.1 CDS mdmC NC_011134.1 687643 688314 D similar to ref|YP_282497.1| O-methyltransferase [Streptococcus pyogenes MGAS5005]; 4-O-methyltransferase for the lactone ring of midecamycin and other macrolide antibiotics.; O-methyltransferase MdmC-like 687643..688314 Streptococcus equi subsp. zooepidemicus MGCS10565 6761725 YP_002123044.1 CDS prsA NC_011134.1 688377 689378 D cis/trans isomerase of peptidylprolyl; PPIase; membrane-bound lipoprotein; foldase PrsA 688377..689378 Streptococcus equi subsp. zooepidemicus MGCS10565 6761752 YP_002123045.1 CDS alaS NC_011134.1 689734 692352 D Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; alanyl-tRNA synthetase 689734..692352 Streptococcus equi subsp. zooepidemicus MGCS10565 6761750 YP_002123046.1 CDS sdzD NC_011134.1 692475 693638 R similar to gb|AAS09918.1| phage-encoded extracellular streptodornase D [Streptococcus pyogenes]; deoxyribonuclease; streptodornase D type, SdzD complement(692475..693638) Streptococcus equi subsp. zooepidemicus MGCS10565 6761748 YP_002123047.1 CDS Sez_0669 NC_011134.1 693801 693944 R hypothetical protein complement(693801..693944) Streptococcus equi subsp. zooepidemicus MGCS10565 6761747 YP_002123048.1 CDS Sez_0670 NC_011134.1 694060 695346 D similar to ref|YP_596896.1| peptidoglycan N-acetylglucosamine deacetylase [Streptococcus pyogenes MGAS9429]; peptidoglycan N-acetylglucosamine deacetylase 694060..695346 Streptococcus equi subsp. zooepidemicus MGCS10565 6761718 YP_002123049.1 CDS Sez_0671 NC_011134.1 695616 696698 R similar to ref|YP_280578.1| ATP-dependent RNA helicase [Streptococcus pyogenes MGAS6180]; Has A Helix-Destabilizing Activity. Plays A Key Role In Optimal Cell Growth At Low Temperature And Is Required For Normal Cell Division. Suppressor Of A Mutant Defective In Rpsb Gene For Ribosomal Protein S2.; ATP-dependent RNA helicase DEAD/DEAH box family complement(695616..696698) Streptococcus equi subsp. zooepidemicus MGCS10565 6761741 YP_002123050.1 CDS udk NC_011134.1 696795 697421 D functions in pyrimidine salvage; pyrimidine ribonucleoside kinase; phosphorylates nucleosides or dinucleosides to make UMP or CMP using ATP or GTP as the donor; uridine kinase 696795..697421 Streptococcus equi subsp. zooepidemicus MGCS10565 6761738 YP_002123051.1 CDS Sez_0673 NC_011134.1 697426 697716 D similar to ref|ZP_01818391.1| hypothetical protein CGSSp3BS71_02178 [Streptococcus pneumoniae SP3-BS71]; hypothetical protein 697426..697716 Streptococcus equi subsp. zooepidemicus MGCS10565 6761732 YP_002123052.1 CDS Sez_0674 NC_011134.1 697910 698680 R similar to ref|NP_607474.1| hypothetical protein spyM18_1378 [Streptococcus pyogenes MGAS8232]; hypothetical protein complement(697910..698680) Streptococcus equi subsp. zooepidemicus MGCS10565 6761728 YP_002123053.1 CDS Sez_0675 NC_011134.1 698860 699357 D similar to ref|ZP_00365499.1| COG1956: GAF domain-containing protein [Streptococcus pyogenes M49 591]; GAF domain-containing proteins 698860..699357 Streptococcus equi subsp. zooepidemicus MGCS10565 6761724 YP_002123054.1 CDS dnaX NC_011134.1 699357 701033 D catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the tau chain serves as a scaffold to help in the dimerizaton of the alpha,epsilon and theta core complex; the gamma chain seems to interact with the delta and delta' subunits to transfer the beta subunit on the DNA; DNA polymerase III subunits gamma and tau 699357..701033 Streptococcus equi subsp. zooepidemicus MGCS10565 6761702 YP_002123055.1 CDS Sez_0677 NC_011134.1 701432 701617 D similar to ref|YP_060403.1| hypothetical protein M6_Spy1085 [Streptococcus pyogenes MGAS10394]; hypothetical protein 701432..701617 Streptococcus equi subsp. zooepidemicus MGCS10565 6761717 YP_002123056.1 CDS birA NC_011134.1 701592 702533 R catalyzes the formation of biotinyl-5'-AMP, also acts as a transcriptional repressor of the biotin operon; biotin--protein ligase complement(701592..702533) Streptococcus equi subsp. zooepidemicus MGCS10565 6761715 YP_002123057.1 CDS inlA NC_011134.1 703060 705300 D similar to ref|YP_001198943.1| internalin A precursor [Streptococcus suis 05ZYH33]; Mediates the entry of Listeria monocytogenes into cells.; internalin A precursor InlA 703060..705300 Streptococcus equi subsp. zooepidemicus MGCS10565 6761710 YP_002123058.1 CDS metK NC_011134.1 705644 706849 D catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase; S-adenosylmethionine synthetase 705644..706849 Streptococcus equi subsp. zooepidemicus MGCS10565 6761705 YP_002123059.1 CDS Sez_0681 NC_011134.1 706908 707042 D hypothetical protein 706908..707042 Streptococcus equi subsp. zooepidemicus MGCS10565 6761628 YP_002123060.1 CDS murA NC_011134.1 707165 708424 D adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active; UDP-N-acetylglucosamine 1-carboxyvinyltransferase 707165..708424 Streptococcus equi subsp. zooepidemicus MGCS10565 6761700 YP_002123061.1 CDS Sez_0683 NC_011134.1 708617 708784 D hypothetical protein 708617..708784 Streptococcus equi subsp. zooepidemicus MGCS10565 6761687 YP_002123062.1 CDS Sez_0684 NC_011134.1 708850 710394 D similar to ref|ZP_00783009.1| sugar transporter, [Streptococcus agalactiae H36B]; glucuronide permease 708850..710394 Streptococcus equi subsp. zooepidemicus MGCS10565 6761656 YP_002123063.1 CDS Sez_0685 NC_011134.1 710480 711508 D similar to ref|ZP_00132613.2| COG0524: Sugar kinases, ribokinase family [Haemophilus somnus 2336]; Catalysis of the reaction: ATP + 2-dehydro-3-deoxy-D-gluconate = ADP + beta-L-arabinose 1-phosphate.; 2-dehydro-3-deoxygluconokinase 710480..711508 Streptococcus equi subsp. zooepidemicus MGCS10565 6761697 YP_002123064.1 CDS Sez_0686 NC_011134.1 711529 713319 D similar to emb|CAI72019.1| beta-glucuronidase [Streptococcus equi subsp. zooepidemicus]; beta-D-glucuronidase 711529..713319 Streptococcus equi subsp. zooepidemicus MGCS10565 6761681 YP_002123065.1 CDS Sez_0687 NC_011134.1 713361 714032 D similar to ref|YP_598782.1| Transcriptional regulator, GntR family [Streptococcus pyogenes MGAS10270]; May be a regulatory protein for the LCT genes.; L-lactate dehydrogenase operon regulatory protein 713361..714032 Streptococcus equi subsp. zooepidemicus MGCS10565 6761696 YP_002123066.1 CDS kdgA NC_011134.1 714225 714842 D similar to ref|YP_598781.1| 4-Hydroxy-2-oxoglutarate aldolase / 2-dehydro-3-deoxyphosphogluconate aldolase [Streptococcus pyogenes MGAS10270]; Key enzyme in the Enter-Duodoroff pathway. Participates in the regulation of the intracellular level of glyoxylate.; KHG/KDPG aldolase KdgA 714225..714842 Streptococcus equi subsp. zooepidemicus MGCS10565 6761677 YP_002123067.1 CDS Sez_0689 NC_011134.1 714873 716270 D catalyzes the interconversion of D-glucuronate to D-fructuronate or D-galacturonate to D-tagaturonate; functions in glucuronic and galacturonic metabolism; glucuronate isomerase 714873..716270 Streptococcus equi subsp. zooepidemicus MGCS10565 6761694 YP_002123068.1 CDS Sez_0690 NC_011134.1 716525 717619 D catalyzes the formation of 2-dehydro-3-deoxy-D-gluconate from mannonate; mannonate dehydratase 716525..717619 Streptococcus equi subsp. zooepidemicus MGCS10565 6761631 YP_002123069.1 CDS Sez_0691 NC_011134.1 717634 718473 D Converts D-mannonate to D-mannuronate; D-mannonate oxidoreductase 717634..718473 Streptococcus equi subsp. zooepidemicus MGCS10565 6761667 YP_002123070.1 CDS Sez_0692 NC_011134.1 718727 719542 D similar to ref|YP_598777.1| Phosphoglycolate phosphatase [Streptococcus pyogenes MGAS10270]; hydrolase HAD family 718727..719542 Streptococcus equi subsp. zooepidemicus MGCS10565 6761690 YP_002123071.1 CDS Sez_0695 NC_011134.1 721791 721931 D hypothetical protein 721791..721931 Streptococcus equi subsp. zooepidemicus MGCS10565 6761660 YP_002123072.1 CDS zag NC_011134.1 721988 723325 D similar to dbj|BAD00711.2| cell surface protein precursor [Streptococcus equi subsp. zooepidemicus]; Binds to the constant Fc region of IgG with high affinity.; IgG binding protein Zag 721988..723325 Streptococcus equi subsp. zooepidemicus MGCS10565 6761682 YP_002123073.1 CDS Sez_0697 NC_011134.1 723620 724174 D similar to ref|NP_735312.1| hypothetical protein gbs0862 [Streptococcus agalactiae NEM316]; GNAT family acetyltransferase 723620..724174 Streptococcus equi subsp. zooepidemicus MGCS10565 6761653 YP_002123074.1 CDS Sez_0698 NC_011134.1 724167 725450 D similar to ref|YP_602697.1| Cytosolic protein containing multiple CBS domains [Streptococcus pyogenes MGAS10750]; cytosolic protein containing multiple CBS domains 724167..725450 Streptococcus equi subsp. zooepidemicus MGCS10565 6761678 YP_002123075.1 CDS map NC_011134.1 725467 727266 D similar to ref|YP_280563.1| methionine aminopeptidase [Streptococcus pyogenes MGAS6180]; Removes the amino-terminal methionine from nascent proteins.; methionine aminopeptidase Map 725467..727266 Streptococcus equi subsp. zooepidemicus MGCS10565 6761680 YP_002123076.1 CDS aroA NC_011134.1 727400 728683 D catalyzes the formation of 5-O-(1-carboxyvinyl)-3-phosphoshikimate from phosphoenolpyruvate and 3-phosphoshikimate in tryptophan biosynthesis; 3-phosphoshikimate 1-carboxyvinyltransferase 727400..728683 Streptococcus equi subsp. zooepidemicus MGCS10565 6761672 YP_002123077.1 CDS aroK NC_011134.1 728676 729170 D catalyzes the formation of shikimate 3-phosphate from shikimate in aromatic amino acid biosynthesis; shikimate kinase 728676..729170 Streptococcus equi subsp. zooepidemicus MGCS10565 6761642 YP_002123078.1 CDS Sez_0702 NC_011134.1 729369 730799 D similar to ref|YP_282462.1| transcriptional regulator, LytR family [Streptococcus pyogenes MGAS5005]; Cell envelope-related transcriptional attenuator.; PBP 5 synthesis repressor 729369..730799 Streptococcus equi subsp. zooepidemicus MGCS10565 6761658 YP_002123079.1 CDS Sez_0703 NC_011134.1 730877 732238 D similar to ref|YP_001128325.1| RNA methyltransferase [Streptococcus pyogenes str. Manfredo]; Could be a 23s rRNA (Uracil-5-)-Methyltransferase.; 23S rRNA-methyltransferase 730877..732238 Streptococcus equi subsp. zooepidemicus MGCS10565 6761657 YP_002123080.1 CDS Sez_0704 NC_011134.1 732465 732668 D hypothetical protein 732465..732668 Streptococcus equi subsp. zooepidemicus MGCS10565 6761654 YP_002123081.1 CDS gpmB NC_011134.1 732902 733546 R similar to ref|YP_598099.1| Phosphoglycerate mutase family protein [Streptococcus pyogenes MGAS10270]; phosphoglycerate mutase GpmB complement(732902..733546) Streptococcus equi subsp. zooepidemicus MGCS10565 6761651 YP_002123082.1 CDS Sez_0706 NC_011134.1 733565 733912 R similar to ref|YP_598100.1| hypothetical protein MGAS10270_Spy0491 [Streptococcus pyogenes MGAS10270]; hypothetical protein complement(733565..733912) Streptococcus equi subsp. zooepidemicus MGCS10565 6761602 YP_002123083.1 CDS Sez_0707 NC_011134.1 733927 734406 R similar to ref|ZP_00365794.1| COG2606: Uncharacterized conserved protein [Streptococcus pyogenes M49 591]; transcriptional regulator complement(733927..734406) Streptococcus equi subsp. zooepidemicus MGCS10565 6761641 YP_002123084.1 CDS Sez_0708 NC_011134.1 734567 735130 R similar to ref|YP_598102.1| Thiamine transporter [Streptococcus pyogenes MGAS10270]; thiamine transporter complement(734567..735130) Streptococcus equi subsp. zooepidemicus MGCS10565 6761635 YP_002123085.1 CDS Sez_0709 NC_011134.1 735685 736533 R similar to ref|YP_602013.1| N-acetylmuramoyl-L-alanine amidase [Streptococcus pyogenes MGAS10750]; N-acetylmuramoyl-L-alanine amidase complement(735685..736533) Streptococcus equi subsp. zooepidemicus MGCS10565 6761583 YP_002123086.1 CDS Sez_0710 NC_011134.1 736801 737265 D similar to ref|YP_602014.1| Integral membrane protein [Streptococcus pyogenes MGAS10750]; hypothetical protein 736801..737265 Streptococcus equi subsp. zooepidemicus MGCS10565 6761608 YP_002123087.1 CDS Sez_0711 NC_011134.1 737464 737751 R hypothetical protein complement(737464..737751) Streptococcus equi subsp. zooepidemicus MGCS10565 6761630 YP_002123088.1 CDS gpo NC_011134.1 737829 738332 R similar to ref|YP_598106.1| Glutathione peroxidase [Streptococcus pyogenes MGAS10270]; Catalysis of the reaction: 2 glutathione + H2O2 = oxidized glutathione + 2 H2O.; glutathione peroxidase complement(737829..738332) Streptococcus equi subsp. zooepidemicus MGCS10565 6761597 YP_002123089.1 CDS Sez_0713 NC_011134.1 738325 740139 R similar to ref|YP_279952.1| oligoendopeptidase F [Streptococcus pyogenes MGAS6180]; oligoendopeptidase F-like complement(738325..740139) Streptococcus equi subsp. zooepidemicus MGCS10565 6761623 YP_002123090.1 CDS ppc NC_011134.1 740322 743105 D catalyzes the formation of oxaloacetate from phosphoenolpyruvate; phosphoenolpyruvate carboxylase 740322..743105 Streptococcus equi subsp. zooepidemicus MGCS10565 6761622 YP_002123091.1 CDS ftsW NC_011134.1 743310 744593 D similar to ref|NP_606853.1| cell division protein [Streptococcus pyogenes MGAS8232]; This is a septum-peptidoglycan biosynthetic protein, involved in cell wall formation. Plays a role in the stabilization of the ftsZ ring during cell division.; cell division protein FtsW 743310..744593 Streptococcus equi subsp. zooepidemicus MGCS10565 6761621 YP_002123092.1 CDS Sez_0716 NC_011134.1 744995 745801 D similar to ref|YP_820727.1| Transcriptional regulator, xre family [Streptococcus thermophilus LMD-9]; positive transcriptional regulator MutR family 744995..745801 Streptococcus equi subsp. zooepidemicus MGCS10565 6761620 YP_002123093.1 CDS Sez_0717 NC_011134.1 745878 747173 D similar to ref|YP_139930.1| hypothetical protein stu1512 [Streptococcus thermophilus LMG 18311]; transcriptional regulator 745878..747173 Streptococcus equi subsp. zooepidemicus MGCS10565 6761569 YP_002123094.1 CDS Sez_0718 NC_011134.1 747452 749008 D similar to ref|YP_001034395.1| Bacteriocin ABC-type exporter, ATP binding/permease, [Streptococcus sanguinis SK36]; multidrug resistance ABC transporter ATP-binding protein/permease 747452..749008 Streptococcus equi subsp. zooepidemicus MGCS10565 6761589 YP_002123095.1 CDS Sez_0719 NC_011134.1 749018 750580 D similar to ref|YP_001034395.1| Bacteriocin ABC-type exporter, ATP binding/permease, [Streptococcus sanguinis SK36]; multidrug resistance ABC transporter ATP-binding protein/permease 749018..750580 Streptococcus equi subsp. zooepidemicus MGCS10565 6761617 YP_002123096.1 CDS Sez_0720 NC_011134.1 750644 750805 R hypothetical protein complement(750644..750805) Streptococcus equi subsp. zooepidemicus MGCS10565 6761614 YP_002123097.1 CDS prfB NC_011134.1 751054 752070 D recognizes the termination signals UGA and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF2; in some organisms control of PrfB protein levels is maintained through a +1 ribosomal frameshifting mechanism; this protein is similar to release factor 1; peptide chain release factor 2 751054..752070 Streptococcus equi subsp. zooepidemicus MGCS10565 6761610 YP_002123098.1 CDS ftsE NC_011134.1 752136 752813 D similar to ref|NP_268888.1| cell-division ATP-binding protein [Streptococcus pyogenes M1 GAS]; cell division ATP-binding protein FtsE 752136..752813 Streptococcus equi subsp. zooepidemicus MGCS10565 6761581 YP_002123099.1 CDS ftsX NC_011134.1 752890 753735 D similar to ref|YP_059871.1| Cell division protein FtsX [Streptococcus pyogenes MGAS10394]; cell division protein FtsX 752890..753735 Streptococcus equi subsp. zooepidemicus MGCS10565 6761600 YP_002123100.1 CDS Sez_0724 NC_011134.1 754251 754892 R similar to ref|YP_001197921.1| Zn-dependent hydrolase, including glyoxylases [Streptococcus suis 05ZYH33]; hydroxyacylglutathione hydrolase complement(754251..754892) Streptococcus equi subsp. zooepidemicus MGCS10565 6761596 YP_002123101.1 CDS dinG NC_011134.1 755230 757695 D unwinds DNA; bifunctional ATP-dependent DNA helicase/DNA polymerase III subunit epsilon 755230..757695 Streptococcus equi subsp. zooepidemicus MGCS10565 6761570 YP_002123102.1 CDS Sez_0726 NC_011134.1 757807 758196 D similar to ref|YP_001450579.1| hypothetical protein SGO_1298 [Streptococcus gordonii str. Challis substr. CH1]; hypothetical protein 757807..758196 Streptococcus equi subsp. zooepidemicus MGCS10565 6761588 YP_002123103.1 CDS Sez_0727 NC_011134.1 758193 759404 D catalyzes the formation of oxalozcetate and L-glutamate from L-aspartate and 2-oxoglutarate; aspartate aminotransferase 758193..759404 Streptococcus equi subsp. zooepidemicus MGCS10565 6761566 YP_002123104.1 CDS asnC NC_011134.1 759417 760763 D catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; asparaginyl-tRNA synthetase 759417..760763 Streptococcus equi subsp. zooepidemicus MGCS10565 6761587 YP_002123105.1 CDS sclZ.8 NC_011134.1 761064 762095 D similar to gb|AAQ91577.1| collagen-like protein 3 [Streptococcus equi]; Possible adhesin, has a collagen-structural-motif domain composed of 62 Gly-Xaa-Yaa repeats.; hypothetical protein 761064..762095 Streptococcus equi subsp. zooepidemicus MGCS10565 6761585 YP_002123106.1 CDS Sez_0730 NC_011134.1 762624 763514 D similar to ref|NP_268894.1| hypothetical protein SPy_0652 [Streptococcus pyogenes M1 GAS]; hypothetical protein 762624..763514 Streptococcus equi subsp. zooepidemicus MGCS10565 6761582 YP_002123107.1 CDS Sez_0731 NC_011134.1 763511 764488 D similar to ref|YP_279987.1| transporter [Streptococcus pyogenes MGAS6180]; hypothetical protein 763511..764488 Streptococcus equi subsp. zooepidemicus MGCS10565 6761563 YP_002123108.1 CDS Sez_0732 NC_011134.1 764485 765396 D similar to gb|AAK33617.1| conserved hypothetical protein [Streptococcus pyogenes M1 GAS]; hypothetical protein 764485..765396 Streptococcus equi subsp. zooepidemicus MGCS10565 6761561 YP_002123109.1 CDS Sez_0733 NC_011134.1 765822 766097 D similar to emb|CAA11401.1| InsA protein [Escherichia coli]; transposase IS1 orfA 765822..766097 Streptococcus equi subsp. zooepidemicus MGCS10565 6761559 YP_002123110.1 CDS Sez_0734 NC_011134.1 766016 766519 D similar to ref|NP_414562.1| IS1 transposase InsAB' [Escherichia coli K12]; transposase IS1 orfB 766016..766519 Streptococcus equi subsp. zooepidemicus MGCS10565 6761552 YP_002123111.1 CDS pepDA NC_011134.1 766539 767936 D similar to ref|YP_279989.1| dipeptidase [Streptococcus pyogenes MGAS6180]; dipeptidase A PepDA 766539..767936 Streptococcus equi subsp. zooepidemicus MGCS10565 6761568 YP_002123112.1 CDS znuA NC_011134.1 768171 769721 D similar to ref|YP_059881.1| High-affinity zinc uptake system protein znuA precursor [Streptococcus pyogenes MGAS10394]; Part of the ATP-driven transport system adcABC for zinc.; zinc-binding lipoprotein ZnuA 768171..769721 Streptococcus equi subsp. zooepidemicus MGCS10565 6761567 YP_002123113.1 CDS Sez_0737 NC_011134.1 770066 770794 D similar to ref|YP_602121.1| Transcriptional regulator, GntR family [Streptococcus pyogenes MGAS10750]; GntR family transcriptional regulator 770066..770794 Streptococcus equi subsp. zooepidemicus MGCS10565 6761565 YP_002123114.1 CDS Sez_0738 NC_011134.1 770806 771981 D similar to ref|YP_001128798.1| tagatose-6-phosphate aldose/ketose isomerase [Streptococcus pyogenes str. Manfredo]; May be a tagatose-6-phosphate ketose/aldose isomerase.; tagatose-6-phosphate ketose/aldose isomerase 770806..771981 Streptococcus equi subsp. zooepidemicus MGCS10565 6761564 YP_002123115.1 CDS Sez_0739 NC_011134.1 771991 772986 D catalyzes the reversible reaction of dihydroxyacetone phosphate with glyceraldehyde 3-phosphate to produce tagatose 1,6-bisphosphate; in Streptococcus pyogenes there are two paralogs of tagatose-bisphosphate aldolase, encoded by lacD1 and lacD2; expression of lacD1 is highly regulated by environmental conditions while lacD2 specializes in an efficient utilization of carbohydrate sources; tagatose 1,6-diphosphate aldolase 771991..772986 Streptococcus equi subsp. zooepidemicus MGCS10565 6761543 YP_002123116.1 CDS Sez_0740 NC_011134.1 773028 773747 R similar to ref|YP_001197814.1| Transcriptional regulator [Streptococcus suis 05ZYH33]; GntR family transcriptional regulator complement(773028..773747) Streptococcus equi subsp. zooepidemicus MGCS10565 6761533 YP_002123117.1 CDS bga NC_011134.1 773887 775671 D similar to ref|ZP_00875460.1| Beta-galactosidase [Streptococcus suis 89/1591]; Preferentially hydrolyzes beta(1->3) galactosyl linkages over beta(1->4) linkages.; beta-galactosidase precursor Bga 773887..775671 Streptococcus equi subsp. zooepidemicus MGCS10565 6761532 YP_002123118.1 CDS Sez_0742 NC_011134.1 775668 776153 D similar to ref|YP_001197816.1| Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIB [Streptococcus suis 05ZYH33]; LevD and levE act as negative regulators of the levanase operon. They may be involved in a PTS-mediated phosphorylation of a regulator.; PTS system mannose/fructose transporter subunit IIB 775668..776153 Streptococcus equi subsp. zooepidemicus MGCS10565 6761556 YP_002123119.1 CDS Sez_0743 NC_011134.1 776199 777080 D similar to ref|NP_344611.1| PTS system, IIC component [Streptococcus pneumoniae TIGR4]; The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. This system is involved in fructose transport.; PTS system mannose/fructose transporter subunit IIC 776199..777080 Streptococcus equi subsp. zooepidemicus MGCS10565 6761553 YP_002123120.1 CDS Sez_0744 NC_011134.1 777067 777885 D similar to ref|ZP_00875457.1| PTS system mannose/fructose/sorbose family IID component [Streptococcus suis 89/1591]; The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. This system is involved in mannose transport.; PTS system mannose/fructose permease IID 777067..777885 Streptococcus equi subsp. zooepidemicus MGCS10565 6761529 YP_002123121.1 CDS Sez_0745 NC_011134.1 777889 778293 D similar to ref|ZP_00875456.1| PTS system fructose subfamily IIA component [Streptococcus suis 89/1591]; The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active-transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. This system is involved in mannose transport.; PTS system mannose/fructose transporter subunit IIAB 777889..778293 Streptococcus equi subsp. zooepidemicus MGCS10565 6761526 YP_002123122.1 CDS rpmE2 NC_011134.1 778400 778660 R RpmE2; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster do not have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome; 50S ribosomal protein L31 complement(778400..778660) Streptococcus equi subsp. zooepidemicus MGCS10565 6761548 YP_002123123.1 CDS Sez_0747 NC_011134.1 778785 779717 R similar to ref|YP_281910.1| phosphoesterase, DHH family protein [Streptococcus pyogenes MGAS5005]; DHH subfamily 1 protein complement(778785..779717) Streptococcus equi subsp. zooepidemicus MGCS10565 6761545 YP_002123124.1 CDS Sez_0748 NC_011134.1 779727 780155 R similar to ref|YP_001344360.1| GCN5-related N-acetyltransferase [Actinobacillus succinogenes 130Z]; acetyltransferase complement(779727..780155) Streptococcus equi subsp. zooepidemicus MGCS10565 6761542 YP_002123125.1 CDS add NC_011134.1 780412 781437 D similar to ref|YP_139256.1| adenosine deaminase [Streptococcus thermophilus LMG 18311]; Catalysis of the reaction: adenosine + H2O = inosine + NH3.; adenosine deaminase 780412..781437 Streptococcus equi subsp. zooepidemicus MGCS10565 6761538 YP_002123126.1 CDS Sez_0750 NC_011134.1 781498 781944 D An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group; flavodoxin 781498..781944 Streptococcus equi subsp. zooepidemicus MGCS10565 6761537 YP_002123127.1 CDS Sez_0751 NC_011134.1 782265 782561 D similar to emb|CAM30580.1| chorismate mutase type II protein [Streptococcus pyogenes str. Manfredo]; Catalysis of the reaction: chorismate = prephenate.; hypothetical protein 782265..782561 Streptococcus equi subsp. zooepidemicus MGCS10565 6761507 YP_002123128.1 CDS Sez_0752 NC_011134.1 782548 782784 D similar to ref|NP_721660.1| permease, chloride channel [Streptococcus mutans UA159]; chloride channel protein 782548..782784 Streptococcus equi subsp. zooepidemicus MGCS10565 6761527 YP_002123129.1 CDS Sez_0753 NC_011134.1 782794 783774 D similar to ref|YP_281913.1| chloride channel protein [Streptococcus pyogenes MGAS5005]; voltage-gated chloride channel family protein 782794..783774 Streptococcus equi subsp. zooepidemicus MGCS10565 6761525 YP_002123130.1 CDS rplS NC_011134.1 783921 784268 D this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site; 50S ribosomal protein L19 783921..784268 Streptococcus equi subsp. zooepidemicus MGCS10565 6761522 YP_002123131.1 CDS sdzA NC_011134.1 784972 785730 R similar to ref|YP_596326.1| streptodornase [Streptococcus pyogenes MGAS9429]; deozyribonuclease; streptodornase A type SdzA complement(784972..785730) Streptococcus equi subsp. zooepidemicus MGCS10565 6760664 YP_002123132.1 CDS ptx NC_011134.1 785896 786108 D similar to ref|YP_598462.1| phage protein [Streptococcus phage 10270.2]; paratox phage protein 785896..786108 Streptococcus equi subsp. zooepidemicus MGCS10565 6761523 YP_002123133.1 CDS Sez_0757 NC_011134.1 786390 786605 D similar to ref|NP_664861.1| transcriptional regulator protein [Streptococcus pyogenes MGAS315]; Cro/CI family transcriptional regulator 786390..786605 Streptococcus equi subsp. zooepidemicus MGCS10565 6761519 YP_002123134.1 CDS Sez_0758 NC_011134.1 786683 787378 D similar to ref|ZP_00785582.1| membrane protein, [Streptococcus agalactiae COH1]; hypothetical protein 786683..787378 Streptococcus equi subsp. zooepidemicus MGCS10565 6761510 YP_002123135.1 CDS Sez_0759 NC_011134.1 787448 788659 R similar to ref|YP_598804.1| Chloride channel protein [Streptococcus pyogenes MGAS10270]; chloride channel protein complement(787448..788659) Streptococcus equi subsp. zooepidemicus MGCS10565 6761492 YP_002123136.1 CDS nrdF NC_011134.1 788789 789748 R B2 or R2 protein; type 1b enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdE; ribonucleotide-diphosphate reductase subunit beta complement(788789..789748) Streptococcus equi subsp. zooepidemicus MGCS10565 6761508 YP_002123137.1 CDS nrdH NC_011134.1 792100 792276 R similar to ref|NP_802075.1| glutaredoxin [Streptococcus pyogenes SSI-1]; Electron transport system for the ribonucleotide reductase system nrdEF.; glutaredoxin-like protein NrdH complement(792100..792276) Streptococcus equi subsp. zooepidemicus MGCS10565 6761504 YP_002123138.1 CDS ptsH NC_011134.1 792740 793003 D similar to ref|YP_329567.1| phosphocarrier protein HPr [Streptococcus agalactiae A909]; P-Ser-HPr interacts with the catabolite control protein A (ccpA), forming a complex that binds to DNA at the catabolite reponse elements cre, operator sites preceding a large number of catabolite-regulated genes. Thus, P-Ser-HPr is a corepressor in carbon catabolite repression (CCR), a mechanism that allows bacteria to coordinate and optimise the utilization of available carbon sources. P-Ser-HPr also plays a role in inducer exclusion, in which it probably interacts with several non-PTS permeases and inhibits their transport activity.; phosphocarrier protein HPr 792740..793003 Streptococcus equi subsp. zooepidemicus MGCS10565 6761500 YP_002123139.1 CDS ptsI NC_011134.1 793008 794741 D similar to ref|NP_269478.1| phosphoenolpyruvate:sugar phosphotransferase system enzyme I [Streptococcus pyogenes M1 GAS]; This is a component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr). Enzyme I is common to all PTS.; phosphoenolpyruvate-protein phosphotransferase PtsI 793008..794741 Streptococcus equi subsp. zooepidemicus MGCS10565 6761498 YP_002123140.1 CDS gapN NC_011134.1 794941 796368 D similar to ref|YP_001128305.1| NADP-dependent glyceraldehyde-3-phosphate dehydrogenase [Streptococcus pyogenes str. Manfredo]; 4-aminobutyrate (GABA) degradation.; NADP-dependent glyceraldehyde-3-phosphate dehydrogenase GapN 794941..796368 Streptococcus equi subsp. zooepidemicus MGCS10565 6761483 YP_002123141.1 CDS ftsW NC_011134.1 797019 798233 D similar to ref|ZP_00790437.1| cell division protein, FtsW/RodA/SpoVE family [Streptococcus agalactiae 515]; cell division protein FtsW 797019..798233 Streptococcus equi subsp. zooepidemicus MGCS10565 6761494 YP_002123142.1 CDS Sez_0768 NC_011134.1 798348 798899 D similar to ref|YP_280000.1| DNA gyrase related protein [Streptococcus pyogenes MGAS6180]; hydrolase HAD family 798348..798899 Streptococcus equi subsp. zooepidemicus MGCS10565 6761493 YP_002123143.1 CDS gyrB NC_011134.1 798900 800852 D negatively supercoils closed circular double-stranded DNA; DNA gyrase subunit B 798900..800852 Streptococcus equi subsp. zooepidemicus MGCS10565 6761476 YP_002123144.1 CDS ezrA NC_011134.1 801001 802725 D acts to negatively regulates ftsZ ring formation by modulating the frequency and position of the ftsZ ring formation; septation ring formation regulator EzrA 801001..802725 Streptococcus equi subsp. zooepidemicus MGCS10565 6761491 YP_002123145.1 CDS Sez_0771 NC_011134.1 802762 802950 D hypothetical protein 802762..802950 Streptococcus equi subsp. zooepidemicus MGCS10565 6761489 YP_002123146.1 CDS Sez_0772 NC_011134.1 803098 803373 D hypothetical protein 803098..803373 Streptococcus equi subsp. zooepidemicus MGCS10565 6761490 YP_002123147.1 CDS Sez_0773 NC_011134.1 803557 804030 R similar to ref|YP_598223.1| hypothetical cytosolic protein [Streptococcus pyogenes MGAS10270]; hypothetical protein complement(803557..804030) Streptococcus equi subsp. zooepidemicus MGCS10565 6761472 YP_002123148.1 CDS eno NC_011134.1 804244 805551 D enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis; phosphopyruvate hydratase 804244..805551 Streptococcus equi subsp. zooepidemicus MGCS10565 6761486 YP_002123149.1 CDS Sez_0776 NC_011134.1 806572 806793 D similar to ref|YP_001198867.1| hypothetical protein SSU05_1501 [Streptococcus suis 05ZYH33]; hypothetical protein 806572..806793 Streptococcus equi subsp. zooepidemicus MGCS10565 6761484 YP_002123150.1 CDS Sez_0777 NC_011134.1 806795 807055 D similar to ref|YP_001198866.1| Cytotoxic translational repressor of toxin-antitoxin stability system [Streptococcus suis 05ZYH33]; plasmid addiction system poison protein 806795..807055 Streptococcus equi subsp. zooepidemicus MGCS10565 6761466 YP_002123151.1 CDS Sez_0778 NC_011134.1 807135 807650 D similar to ref|NP_688076.1| IS861, transposase OrfA [Streptococcus agalactiae 2603V/R]; transposase IS861 orfA 807135..807650 Streptococcus equi subsp. zooepidemicus MGCS10565 6761478 YP_002123152.1 CDS Sez_0779 NC_011134.1 807647 808366 D similar to ref|NP_721000.1| transposase, ISSmu1 [Streptococcus mutans UA159]; transposase IS861 orfB 807647..808366 Streptococcus equi subsp. zooepidemicus MGCS10565 6761479 YP_002123153.1 CDS Sez_0780 NC_011134.1 808548 808808 D similar to gb|AAA37416.1| complement factor H-related protein; hypothetical protein 808548..808808 Streptococcus equi subsp. zooepidemicus MGCS10565 6761477 YP_002123154.1 CDS Sez_0781 NC_011134.1 808836 811616 D similar to ref|YP_596357.1| endonuclease/exonuclease/phosphatase family protein [Streptococcus pyogenes MGAS9429]; extracellular nuclease 808836..811616 Streptococcus equi subsp. zooepidemicus MGCS10565 6761460 YP_002123155.1 CDS Sez_0782 NC_011134.1 812206 812328 D hypothetical protein 812206..812328 Streptococcus equi subsp. zooepidemicus MGCS10565 6761430 YP_002123156.1 CDS Sez_0783 NC_011134.1 812419 812925 D similar to ref|ZP_00365711.1| COG4708: Predicted membrane protein [Streptococcus pyogenes M49 591]; hypothetical protein 812419..812925 Streptococcus equi subsp. zooepidemicus MGCS10565 6761459 YP_002123157.1 CDS ligA NC_011134.1 813022 814980 D this protein catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction; essential for DNA replication and repair of damaged DNA; similar to ligase LigB; NAD-dependent DNA ligase LigA 813022..814980 Streptococcus equi subsp. zooepidemicus MGCS10565 6761473 YP_002123158.1 CDS Sez_0785 NC_011134.1 814993 816015 D similar to YegS from E. coli; lipid kinase 814993..816015 Streptococcus equi subsp. zooepidemicus MGCS10565 6761471 YP_002123159.1 CDS pulA NC_011134.1 816024 818324 D similar to ref|NP_721883.1| glycogen branching enzyme [Streptococcus mutans UA159]; Hydrolyzes the alpha-1,6-glucosidic linkages in glycogen which has first been partially depolymerized by phosphorylase. Shows only very little activity with native glycogen.; glycogen debranching enzyme / pullulanase PulA 816024..818324 Streptococcus equi subsp. zooepidemicus MGCS10565 6761452 YP_002123160.1 CDS glgB NC_011134.1 818471 820351 D catalyzes the transfer of a segment of a 1,4-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain; glycogen branching protein 818471..820351 Streptococcus equi subsp. zooepidemicus MGCS10565 6761450 YP_002123161.1 CDS glgC NC_011134.1 820428 821555 D catalyzes the formation of ADP-glucose and diphosphate from ATP and alpha-D-glucose 1-phosphate; glucose-1-phosphate adenylyltransferase 820428..821555 Streptococcus equi subsp. zooepidemicus MGCS10565 6761469 YP_002123162.1 CDS glgD NC_011134.1 821545 822678 D similar to ref|NP_721881.1| glycogen biosynthesis protein GlgD [Streptococcus mutans UA159]; Required for the synthesis of glycogen, glucose-1-phosphate adenylyltransferase.; glycogen biosynthesis protein GlgD 821545..822678 Streptococcus equi subsp. zooepidemicus MGCS10565 6761436 YP_002123163.1 CDS glgA NC_011134.1 822684 824105 D catalyzes the formation of alpha-1,4-glucan chains from ADP-glucose; glycogen synthase 822684..824105 Streptococcus equi subsp. zooepidemicus MGCS10565 6761435 YP_002123164.1 CDS glgP NC_011134.1 824118 826520 D similar to ref|NP_721879.1| glycogen phosphorylase [Streptococcus mutans UA159]; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.; glycogen phosphorylase GlgP 824118..826520 Streptococcus equi subsp. zooepidemicus MGCS10565 6761461 YP_002123165.1 CDS atpE NC_011134.1 826862 827059 D produces ATP from ADP in the presence of a proton gradient across the membrane; subunit C is part of the membrane proton channel F0; ATP synthase F0F1 subunit C 826862..827059 Streptococcus equi subsp. zooepidemicus MGCS10565 6761462 YP_002123166.1 CDS atpB NC_011134.1 827093 827809 D Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0; ATP synthase F0F1 subunit A 827093..827809 Streptococcus equi subsp. zooepidemicus MGCS10565 6761432 YP_002123167.1 CDS atpF NC_011134.1 827827 828321 D Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit B is part of the membrane proton channel.; ATP synthase F0F1 subunit B 827827..828321 Streptococcus equi subsp. zooepidemicus MGCS10565 6761457 YP_002123168.1 CDS atpH NC_011134.1 828321 828857 D Produces ATP from ADP in the presence of a proton gradient across the membrane; the delta subunit is part of the catalytic core of the ATP synthase complex; ATP synthase F0F1 subunit delta 828321..828857 Streptococcus equi subsp. zooepidemicus MGCS10565 6761455 YP_002123169.1 CDS atpA NC_011134.1 828873 830378 D produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit; ATP synthase F0F1 subunit alpha 828873..830378 Streptococcus equi subsp. zooepidemicus MGCS10565 6761454 YP_002123170.1 CDS atpG NC_011134.1 830395 831270 D Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is a regulatory subunit; ATP synthase F0F1 subunit gamma 830395..831270 Streptococcus equi subsp. zooepidemicus MGCS10565 6761442 YP_002123171.1 CDS atpD NC_011134.1 831438 832844 D Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit; ATP synthase F0F1 subunit beta 831438..832844 Streptococcus equi subsp. zooepidemicus MGCS10565 6761389 YP_002123172.1 CDS atpC NC_011134.1 832857 833273 D part of catalytic core of ATP synthase; alpha(3)beta(3)gamma(1)delta(1)epsilon(1); involved in producing ATP from ADP in the presence of the proton motive force across the membrane; ATP synthase F0F1 subunit epsilon 832857..833273 Streptococcus equi subsp. zooepidemicus MGCS10565 6761411 YP_002123173.1 CDS Sez_0800 NC_011134.1 833431 833643 D similar to ref|YP_059918.1| Hypothetical membrane associated protein [Streptococcus pyogenes MGAS10394]; hypothetical protein 833431..833643 Streptococcus equi subsp. zooepidemicus MGCS10565 6761431 YP_002123174.1 CDS murA NC_011134.1 833695 834978 D adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active; UDP-N-acetylglucosamine 1-carboxyvinyltransferase 833695..834978 Streptococcus equi subsp. zooepidemicus MGCS10565 6761406 YP_002123175.1 CDS epuA NC_011134.1 835018 835170 D similar to gb|AAK33707.1| conserved competence associated hypothetical protein [Streptococcus pyogenes M1 GAS]; EpuA 835018..835170 Streptococcus equi subsp. zooepidemicus MGCS10565 6761428 YP_002123176.1 CDS endA NC_011134.1 835187 836080 D similar to ref|YP_139616.1| competence associated membrane nuclease [Streptococcus thermophilus LMG 18311]; By degrading DNA that enters the cell, plays a role in the competence of cells to be transformed.; DNA-entry nuclease EndA 835187..836080 Streptococcus equi subsp. zooepidemicus MGCS10565 6761427 YP_002123177.1 CDS Sez_0804 NC_011134.1 836094 836252 D hypothetical protein 836094..836252 Streptococcus equi subsp. zooepidemicus MGCS10565 6761423 YP_002123178.1 CDS pheS NC_011134.1 836995 838038 D catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily; phenylalanyl-tRNA synthetase subunit alpha 836995..838038 Streptococcus equi subsp. zooepidemicus MGCS10565 6761422 YP_002123179.1 CDS pheT NC_011134.1 838228 840633 D catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily; phenylalanyl-tRNA synthetase subunit beta 838228..840633 Streptococcus equi subsp. zooepidemicus MGCS10565 6761416 YP_002123180.1 CDS Sez_0807 NC_011134.1 840870 841946 D similar to ref|YP_001128757.1| permease [Streptococcus pyogenes str. Manfredo]; ABC transporter permease 840870..841946 Streptococcus equi subsp. zooepidemicus MGCS10565 6761390 YP_002123181.1 CDS Sez_0808 NC_011134.1 841956 842660 D similar to dbj|BAF45146.1| ABC transporter ATP-binding protein [Streptococcus equi subsp. zooepidemicus]; ABC transporter ATP-binding protein 841956..842660 Streptococcus equi subsp. zooepidemicus MGCS10565 6761415 YP_002123182.1 CDS szp NC_011134.1 843000 844133 D similar to gb|AAD37432.1|AF150748_1 M-like protein precursor [Streptococcus equi subsp. zooepidemicus]; Major surface antigen likely antiphagocytic providing resitancew to host immune response.; M-like proptein Szp 843000..844133 Streptococcus equi subsp. zooepidemicus MGCS10565 6761408 YP_002123183.1 CDS Sez_0810 NC_011134.1 844295 844870 R similar to dbj|BAF45148.1| TetR family transcriptional regulator [Streptococcus equi subsp. zooepidemicus]; TetR family transcriptional regulator complement(844295..844870) Streptococcus equi subsp. zooepidemicus MGCS10565 6761407 YP_002123184.1 CDS fszA NC_011134.1 844924 846921 D similar to gb|AAO43099.1| collagen-binding protein Cne precursor [Streptococcus equi subsp. equi]; Mediates attachment of cells to collagen- containing substrata, fimbrial protein.; fimbrial subunit A protein FszA 844924..846921 Streptococcus equi subsp. zooepidemicus MGCS10565 6761379 YP_002123185.1 CDS fszB NC_011134.1 846936 848372 D similar to gb|AAM77659.1|AF521601_1 surface protein se51.9 [Streptococcus equi]; Fimbrial subunit-like protein, adhesin.; fimbrial subunit B protein FszB 846936..848372 Streptococcus equi subsp. zooepidemicus MGCS10565 6761399 YP_002123186.1 CDS srtC.1 NC_011134.1 848453 849262 D similar to ref|YP_001035569.1| Sortase-like protein, [Streptococcus sanguinis SK36]; Fimbrial associated sortase required for polymerization of fimbrial subunits.; sortase 848453..849262 Streptococcus equi subsp. zooepidemicus MGCS10565 6761397 YP_002123187.1 CDS ideZ NC_011134.1 849577 850755 D similar to pdb|2AU1|A Chain A, Crystal Structure Of Group A Streptococcus Mac-1 Orthorhombic Form; Virulence protein involved in evasion of the host immune response.; Mac-1-like IgG-degrading endopeptidase IdeZ 849577..850755 Streptococcus equi subsp. zooepidemicus MGCS10565 6761370 YP_002123188.1 CDS Sez_0815 NC_011134.1 850835 852037 D similar to emb|CAA36712.1| proline-rich protein [Triticum aestivum]; hypothetical protein 850835..852037 Streptococcus equi subsp. zooepidemicus MGCS10565 6761394 YP_002123189.1 CDS Sez_0816 NC_011134.1 852207 852755 R similar to ref|ZP_01817173.1| hypothetical protein CGSSp3BS71_06969 [Streptococcus pneumoniae SP3-BS71]; hypothetical protein complement(852207..852755) Streptococcus equi subsp. zooepidemicus MGCS10565 6761395 YP_002123190.1 CDS Sez_0817 NC_011134.1 852748 853035 R similar to ref|NP_344990.1| hypothetical protein SP_0471 [Streptococcus pneumoniae TIGR4]; hypothetical protein complement(852748..853035) Streptococcus equi subsp. zooepidemicus MGCS10565 6761367 YP_002123191.1 CDS Sez_0818 NC_011134.1 853035 853418 R hypothetical protein complement(853035..853418) Streptococcus equi subsp. zooepidemicus MGCS10565 6761388 YP_002123192.1 CDS pulA NC_011134.1 854598 858314 D similar to ref|YP_001034451.1| Type II secretory pathway, pullulanase PulA glycosidase, [Streptococcus sanguinis SK36]; Hydrolyzes The Alpha-1,6-Glucosidic Linkages In Glycogen Which Has First Been Partially Depolymerized By Phosphorylase. Shows Only Very Little Activity With Native Glycogen.; pullulanase precursor PulA 854598..858314 Streptococcus equi subsp. zooepidemicus MGCS10565 6761385 YP_002123193.1 CDS rpoE NC_011134.1 858603 859142 D similar to ref|ZP_01573929.1| RNA polymerase, sigma-24 subunit, ECF subfamily [Clostridium cellulolyticum H10]; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in heat shock and oxidative stress response; it is believed to control protein processing in the extracytoplasmic compartment.; RNA polymerase sigma-E factor RpoE 858603..859142 Streptococcus equi subsp. zooepidemicus MGCS10565 6761358 YP_002123194.1 CDS Sez_0822 NC_011134.1 859189 859767 D hypothetical protein 859189..859767 Streptococcus equi subsp. zooepidemicus MGCS10565 6761376 YP_002123195.1 CDS Sez_0823 NC_011134.1 859826 860590 D similar to ref|NP_688548.1| hypothetical protein SAG1555 [Streptococcus agalactiae 2603V/R]; hypothetical protein 859826..860590 Streptococcus equi subsp. zooepidemicus MGCS10565 6761378 YP_002123196.1 CDS Sez_0824 NC_011134.1 860604 861281 D similar to ref|ZP_00783577.1| conserved hypothetical protein [Streptococcus agalactiae H36B]; hypothetical protein 860604..861281 Streptococcus equi subsp. zooepidemicus MGCS10565 6761377 YP_002123197.1 CDS Sez_0825 NC_011134.1 861287 862720 D similar to ref|ZP_00783579.1| Unknown [Streptococcus agalactiae H36B]; hypothetical protein 861287..862720 Streptococcus equi subsp. zooepidemicus MGCS10565 6761372 YP_002123198.1 CDS Sez_0826 NC_011134.1 862727 864868 D similar to gb|ABA44760.1| conserved hypothetical protein [Streptococcus agalactiae A909]; hypothetical protein 862727..864868 Streptococcus equi subsp. zooepidemicus MGCS10565 6760895 YP_002123199.1 CDS Sez_0827 NC_011134.1 865015 866409 D similar to ref|YP_330175.1| glycosyl transferase, group 2 family protein [Streptococcus agalactiae A909]; glycosyl transferase family protein 865015..866409 Streptococcus equi subsp. zooepidemicus MGCS10565 6760997 YP_002123200.1 CDS addB NC_011134.1 866527 869841 D similar to ref|YP_280042.1| ATP-dependent nuclease subunit B [Streptococcus pyogenes MGAS6180]; The enzyme complex may have a wide variety of catalytic activities including ATP-dependent exonuclease, ATP-stimulated endonuclease, ATP-dependent helicase and DNA-dependent ATPase activities.; ATP-dependent nuclease subunit B AddB 866527..869841 Streptococcus equi subsp. zooepidemicus MGCS10565 6760438 YP_002123201.1 CDS addA NC_011134.1 869831 873475 D similar to ref|NP_664318.1| ATP-dependent exonuclease subunit A [Streptococcus pyogenes MGAS315]; The enzyme complex may have a wide variety of catalytic activities including ATP-dependent exonuclease, ATP-stimulated endonuclease, ATP-dependent helicase and DNA-dependent ATPase activities. The subunit A may have a role in DNA unwinding (helicase), and in the nuclease activity.; ATP-dependent nuclease subunit A AddA 869831..873475 Streptococcus equi subsp. zooepidemicus MGCS10565 6762157 YP_002123202.1 CDS aspC NC_011134.1 873741 874856 D associated with arginine deiminase pathway genes; probably functions in arginine catabolism; transaminase 873741..874856 Streptococcus equi subsp. zooepidemicus MGCS10565 6760585 YP_002123203.1 CDS Sez_0831 NC_011134.1 874924 875736 D similar to ref|YP_330074.1| polar amino acid uptake (PAAT) family ABC transporter, amino acid-binding protein [Streptococcus agalactiae A909]; Probably part of a binding-protein-dependent transport system for an amino acid.; amino acid ABC transporter, amino acid-binding/permease 874924..875736 Streptococcus equi subsp. zooepidemicus MGCS10565 6760631 YP_002123204.1 CDS rpsU NC_011134.1 875873 876079 D a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA; 30S ribosomal protein S21 875873..876079 Streptococcus equi subsp. zooepidemicus MGCS10565 6760559 YP_002123205.1 CDS mscL NC_011134.1 876307 876681 R similar to ref|NP_268999.1| large conductance mechanosensitive channel [Streptococcus pyogenes M1 GAS]; Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.; large-conductance mechanosensitive channel MscL complement(876307..876681) Streptococcus equi subsp. zooepidemicus MGCS10565 6762219 YP_002123206.1 CDS dnaG NC_011134.1 876928 878739 D synthesizes RNA primers at the replication forks; DNA primase 876928..878739 Streptococcus equi subsp. zooepidemicus MGCS10565 6762199 YP_002123207.1 CDS rpoD NC_011134.1 878748 879857 D sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; primary sigma factor of bacterium; RNA polymerase sigma factor RpoD 878748..879857 Streptococcus equi subsp. zooepidemicus MGCS10565 6760901 YP_002123208.1 CDS Sez_0836 NC_011134.1 880176 880547 D similar to ref|NP_269002.1| hypothetical protein SPy_0783 [Streptococcus pyogenes M1 GAS]; hypothetical protein 880176..880547 Streptococcus equi subsp. zooepidemicus MGCS10565 6762229 YP_002123209.1 CDS Sez_0837 NC_011134.1 880688 881536 D similar to ref|YP_602183.1| dTDP-4-dehydrorhamnose reductase [Streptococcus pyogenes MGAS10750]; Catalysis of the reaction: dTDP-6-deoxy-L-mannose + NADP+ = dTDP-4-dehydro-6-deoxy-L-mannose + NADPH + H+.; dTDP-4-dehydrorhamnose reductase 880688..881536 Streptococcus equi subsp. zooepidemicus MGCS10565 6760900 YP_002123210.1 CDS Sez_0838 NC_011134.1 881661 882815 D similar to ref|YP_059938.1| alpha-D-GlcNAc alpha-1,2-L-rhamnosyltransferase [Streptococcus pyogenes MGAS10394]; alpha-D-GlcNAc alpha-1,2-L-rhamnosyltransferase 881661..882815 Streptococcus equi subsp. zooepidemicus MGCS10565 6760904 YP_002123211.1 CDS Sez_0839 NC_011134.1 882805 883740 D similar to ref|YP_598268.1| alpha-L-Rha alpha-1,3-L-rhamnosyltransferase [Streptococcus pyogenes MGAS10270]; alpha-L-Rha alpha-1,3-L-rhamnosyltransferase 882805..883740 Streptococcus equi subsp. zooepidemicus MGCS10565 6762250 YP_002123212.1 CDS Sez_0840 NC_011134.1 883740 884543 D similar to ref|YP_281968.1| polysaccharide export ABC transporter permease [Streptococcus pyogenes MGAS5005]; Possibly involved in GCS group carbohydrate antigen synthesis.; rhamnose-containing polysacharide translocation permease 883740..884543 Streptococcus equi subsp. zooepidemicus MGCS10565 6762227 YP_002123213.1 CDS Sez_0841 NC_011134.1 884543 885751 D similar to ref|ZP_00366290.1| COG1134: ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Streptococcus pyogenes M49 591]; Possibly involved in cell wall localization and side chain formation of rhamnose-glucose polysaccharide.; ABC transporter ATP-binding protein 884543..885751 Streptococcus equi subsp. zooepidemicus MGCS10565 6762275 YP_002123214.1 CDS Sez_0842 NC_011134.1 885772 886779 D similar to ref|YP_001128742.1| glycosyltransferase [Streptococcus pyogenes str. Manfredo]; Possibly involved in cell wall localization and side chain formation of rhamnose-glucose polysaccharide.; glycosyltransferase 885772..886779 Streptococcus equi subsp. zooepidemicus MGCS10565 6762233 YP_002123215.1 CDS Sez_0843 NC_011134.1 886776 888521 D similar to ref|YP_001128741.1| rhamnan synthesis protein F family protein [Streptococcus pyogenes str. Manfredo]; Possibly involved in synthesis of the GCS carbohydrate group antigen.; alpha-L-Rha alpha-1,3-L-rhamnosyltransferase 886776..888521 Streptococcus equi subsp. zooepidemicus MGCS10565 6762281 YP_002123216.1 CDS Sez_0844 NC_011134.1 888551 889240 D similar to ref|YP_141826.1| glycosyl transferase [Streptococcus thermophilus CNRZ1066]; Possibly involved in synthesis of the GCS carbohydrate group antigen.; glycosyl transferase family protein 888551..889240 Streptococcus equi subsp. zooepidemicus MGCS10565 6762241 YP_002123217.1 CDS Sez_0845 NC_011134.1 889245 889601 D similar to ref|YP_141825.1| hypothetical protein str1475 [Streptococcus thermophilus CNRZ1066]; Possibly involved in synthesis of the GCS carbohydrate group antigen.; glycosyltransferase, lytic transglycosylase, dTDP-4-rhamnose reductase 889245..889601 Streptococcus equi subsp. zooepidemicus MGCS10565 6760907 YP_002123218.1 CDS Sez_0846 NC_011134.1 889636 890826 D similar to ref|YP_001128737.1| exopolysaccharide biosynthesis protein [Streptococcus pyogenes str. Manfredo]; Possibly involved in synthesis of the GCS carbohydrate group antigen.; heteropolysaccharide repeat unit export protein 889636..890826 Streptococcus equi subsp. zooepidemicus MGCS10565 6762228 YP_002123219.1 CDS Sez_0847 NC_011134.1 890830 892314 D similar to ref|YP_280061.1| hypothetical membrane spanning protein [Streptococcus pyogenes MGAS6180]; hypothetical protein 890830..892314 Streptococcus equi subsp. zooepidemicus MGCS10565 6762249 YP_002123220.1 CDS Sez_0848 NC_011134.1 892328 893491 D similar to ref|ZP_00785358.1| glycosyl transferase, group 1 family protein [Streptococcus agalactiae COH1]; Possibly involved in synthesis of the GCS carbohydrate group antigen.; glycosyl transferase family protein 892328..893491 Streptococcus equi subsp. zooepidemicus MGCS10565 6760910 YP_002123221.1 CDS Sez_0849 NC_011134.1 893576 895945 D similar to ref|NP_721241.1| hypothetical protein SMU.831 [Streptococcus mutans UA159]; phosphoglycerol transferase 893576..895945 Streptococcus equi subsp. zooepidemicus MGCS10565 6762282 YP_002123222.1 CDS galE NC_011134.1 896013 897032 D similar to ref|ZP_01825231.1| UDP-glucose 4-epimerase [Streptococcus pneumoniae SP11-BS70]; Catalysis of the reaction: UDP-glucose = UDP-galactose.; UDP-glucose 4-epimerase GalE 896013..897032 Streptococcus equi subsp. zooepidemicus MGCS10565 6760911 YP_002123223.1 CDS Sez_0851 NC_011134.1 897044 897205 D hypothetical protein 897044..897205 Streptococcus equi subsp. zooepidemicus MGCS10565 6762290 YP_002123224.1 CDS pepT NC_011134.1 897319 898425 D similar to ref|NP_269015.1| peptidase T [Streptococcus pyogenes M1 GAS]; Releases the N-terminal amino acid from tripeptides. Has a preference for tripeptides containing a N-terminal methionine or leucine.; tripeptide aminopeptidase PepT 897319..898425 Streptococcus equi subsp. zooepidemicus MGCS10565 6762297 YP_002123225.1 CDS ebsA NC_011134.1 898516 898959 D similar to ref|YP_059950.1| Gene info Pore forming protein ebsA [Streptococcus pyogenes MGAS10394]; pore-forming peptide EbsA-like 898516..898959 Streptococcus equi subsp. zooepidemicus MGCS10565 6760915 YP_002123226.1 CDS Sez_0854 NC_011134.1 898946 899143 R similar to ref|NP_269017.1| ferredoxin [Streptococcus pyogenes M1 GAS]; ferredoxin complement(898946..899143) Streptococcus equi subsp. zooepidemicus MGCS10565 6760919 YP_002123227.1 CDS Sez_0855 NC_011134.1 899192 899701 D similar to ref|YP_280065.1| hypothetical membrane associated protein [Streptococcus pyogenes MGAS6180]; hypothetical protein 899192..899701 Streptococcus equi subsp. zooepidemicus MGCS10565 6760918 YP_002123228.1 CDS cmk NC_011134.1 899716 900396 D Catalyzes the formation of (d)CDP from ATP and (d)CMP; cytidylate kinase 899716..900396 Streptococcus equi subsp. zooepidemicus MGCS10565 6762295 YP_002123229.1 CDS infC NC_011134.1 900557 901087 D IF-3 has several functions that are required and promote translation initiation including; preventing association of 70S by binding to 30S; monitoring codon-anticodon interactions by promoting disassociation of fMet-tRNA(fMet) from initiation complexes formed on leaderless mRNAs or incorrectly bound noninitiatior tRNAs and complexes with noncanonical start sites; stimulates codon-anticodon interactions at P-site; involved in moving mRNA to the P-site; and in recycling subunits; translation initiation factor IF-3 900557..901087 Streptococcus equi subsp. zooepidemicus MGCS10565 6762184 YP_002123230.1 CDS rpmI NC_011134.1 901127 901324 D similar to ref|YP_001035443.1| 50S ribosomal protein L35 [Streptococcus sanguinis SK36]; 50S ribosomal protein L35 901127..901324 Streptococcus equi subsp. zooepidemicus MGCS10565 6760923 YP_002123231.1 CDS rplT NC_011134.1 901385 901744 D binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit; 50S ribosomal protein L20 901385..901744 Streptococcus equi subsp. zooepidemicus MGCS10565 6760926 YP_002123232.1 CDS Sez_0860 NC_011134.1 901893 902048 D hypothetical protein 901893..902048 Streptococcus equi subsp. zooepidemicus MGCS10565 6762266 YP_002123233.1 CDS Sez_0861 NC_011134.1 902379 903056 D similar to ref|YP_848744.1| secreted MUCin-binding domain protein [Listeria welshimeri serovar 6b str. SLCC5334]; Unknown, possibly involved in mucin-binding.; cell wall surface anchor family protein 902379..903056 Streptococcus equi subsp. zooepidemicus MGCS10565 6760925 YP_002123234.1 CDS Sez_0862 NC_011134.1 903168 905354 R similar to ref|YP_602203.1| Sulfatase family protein [Streptococcus pyogenes MGAS10750]; phosphoglycerol transferase complement(903168..905354) Streptococcus equi subsp. zooepidemicus MGCS10565 6760929 YP_002123235.1 CDS Sez_0863 NC_011134.1 905502 906665 D similar to ref|YP_281986.1| methyltransferase [Streptococcus pyogenes MGAS5005]; SAM-dependent methyltransferase 905502..906665 Streptococcus equi subsp. zooepidemicus MGCS10565 6760922 YP_002123236.1 CDS aroD NC_011134.1 906662 907342 D catalyzes the dehydration of 3-dehydroquinate to form 3-dehydroshikimate in aromatic amino acid biosynthesis; 3-dehydroquinate dehydratase 906662..907342 Streptococcus equi subsp. zooepidemicus MGCS10565 6762304 YP_002123237.1 CDS aroC NC_011134.1 907455 908621 D catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis; chorismate synthase 907455..908621 Streptococcus equi subsp. zooepidemicus MGCS10565 6760933 YP_002123238.1 CDS Sez_0866 NC_011134.1 908682 909023 D similar to ref|YP_059961.1| Hypothetical cytosolic protein [Streptococcus pyogenes MGAS10394]; hypothetical protein 908682..909023 Streptococcus equi subsp. zooepidemicus MGCS10565 6760927 YP_002123239.1 CDS Sez_0867 NC_011134.1 909217 910569 D catalyzes the reduction of 2 glutathione to glutathione disulfide; maintains high levels of reduced glutathione in the cytosol; involved in redox regulation and oxidative defense; glutathione reductase 909217..910569 Streptococcus equi subsp. zooepidemicus MGCS10565 6762278 YP_002123240.1 CDS Sez_0868 NC_011134.1 910640 911080 R similar to ref|NP_607031.1| hypothetical protein spyM18_0877 [Streptococcus pyogenes MGAS8232]; hypothetical protein complement(910640..911080) Streptococcus equi subsp. zooepidemicus MGCS10565 6762230 YP_002123241.1 CDS iscS NC_011134.1 911320 912462 D similar to ref|YP_598295.1| Cysteine desulfurase / Selenocysteine lyase [Streptococcus pyogenes MGAS10270]; Fe-S cluster biosynthesis.; cysteine desulfurase 911320..912462 Streptococcus equi subsp. zooepidemicus MGCS10565 6760930 YP_002123242.1 CDS thiI NC_011134.1 912482 913678 D Required for the synthesis of the thiazole moiety; thiamine biosynthesis protein ThiI 912482..913678 Streptococcus equi subsp. zooepidemicus MGCS10565 6762316 YP_002123243.1 CDS Sez_0871 NC_011134.1 913802 913993 R hypothetical protein complement(913802..913993) Streptococcus equi subsp. zooepidemicus MGCS10565 6760935 YP_002123244.1 CDS ideZ NC_011134.1 914376 915425 R similar to gb|ABH04315.1| IgG endopeptidase [Streptococcus equi subsp. zooepidemicus]; IgG cleavage resistance to the host immune response.; IgG-degrading enzyme/Mac-1 IdeZ complement(914376..915425) Streptococcus equi subsp. zooepidemicus MGCS10565 6762323 YP_002123245.1 CDS Sez_0874 NC_011134.1 915949 916311 R hypothetical protein complement(915949..916311) Streptococcus equi subsp. zooepidemicus MGCS10565 6762301 YP_002123246.1 CDS Sez_0875 NC_011134.1 917276 918406 R similar to ref|YP_596508.1| transposase [Streptococcus pyogenes MGAS9429]; transposase IS1548-like complement(917276..918406) Streptococcus equi subsp. zooepidemicus MGCS10565 6761194 YP_002123247.1 CDS Sez_0876 NC_011134.1 918483 919118 D similar to ref|YP_060299.1| membrane-associated alkaline phosphatase [Streptococcus pyogenes MGAS10394]; hypothetical protein 918483..919118 Streptococcus equi subsp. zooepidemicus MGCS10565 6760941 YP_002123248.1 CDS Sez_0877 NC_011134.1 919165 919959 R similar to ref|ZP_00365831.1| COG0477: Permeases of the major facilitator superfamily [Streptococcus pyogenes M49 591]; ABC transporter permease complement(919165..919959) Streptococcus equi subsp. zooepidemicus MGCS10565 6760908 YP_002123249.1 CDS Sez_0878 NC_011134.1 919969 920667 R similar to ref|ZP_00365454.1| COG1131: ABC-type multidrug transport system, ATPase component [Streptococcus pyogenes M49 591]; ABC transporter ATP-binding protein complement(919969..920667) Streptococcus equi subsp. zooepidemicus MGCS10565 6760939 YP_002123250.1 CDS Sez_0879 NC_011134.1 920667 921038 R similar to ref|YP_600647.1| Transcriptional regulator, GntR family [Streptococcus pyogenes MGAS2096]; GntR family transcriptional regulator complement(920667..921038) Streptococcus equi subsp. zooepidemicus MGCS10565 6760952 YP_002123251.1 CDS dnaE NC_011134.1 921250 924390 D Catalyzes DNA-template-directed extension of the 3'-end of a DNA strand by one nucleotide at a time. Proposed to be responsible for the synthesis of the lagging strand. In the low GC gram positive bacteria this enzyme is less processive and more error prone than its counterpart in other bacteria.; DNA polymerase III DnaE 921250..924390 Streptococcus equi subsp. zooepidemicus MGCS10565 6760948 YP_002123252.1 CDS pfkA NC_011134.1 924470 925483 D catalyzes the formation of D-fructose 1,6-bisphosphate from D-fructose 6-phosphate in glycolysis; 6-phosphofructokinase 924470..925483 Streptococcus equi subsp. zooepidemicus MGCS10565 6760945 YP_002123253.1 CDS pyk NC_011134.1 925545 927047 D catalyzes the formation of phosphoenolpyruvate from pyruvate; pyruvate kinase 925545..927047 Streptococcus equi subsp. zooepidemicus MGCS10565 6760946 YP_002123254.1 CDS lepB NC_011134.1 927176 927733 D similar to ref|YP_280427.1| signal peptidase I [Streptococcus pyogenes MGAS6180]; signal peptidase I LepB 927176..927733 Streptococcus equi subsp. zooepidemicus MGCS10565 6762350 YP_002123255.1 CDS glmS NC_011134.1 927910 929721 D Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source; glucosamine--fructose-6-phosphate aminotransferase 927910..929721 Streptococcus equi subsp. zooepidemicus MGCS10565 6760954 YP_002123256.1 CDS phnA NC_011134.1 929905 930240 D similar to ref|NP_607338.1| hypothetical protein spyM18_1226 [Streptococcus pyogenes MGAS8232]; Unknown, The PhnA protein family includes the uncharacterised Escherichia coli protein PhnA and its homologues. The E. coli phnA gene is part of a large operon associated with alkylphosphonate uptake and carbon-phosphorus bond cleavage. The protein is not related to the characterised phosphonoacetate hydrolase designated PhnA.; PhnA protein 929905..930240 Streptococcus equi subsp. zooepidemicus MGCS10565 6760956 YP_002123257.1 CDS Sez_0886 NC_011134.1 930359 930988 D similar to ref|YP_602628.1| Histidine transport system permease HisM [Streptococcus pyogenes MGAS10750]; Probably part of a binding-protein-dependent transport system for an amino acid. Probably responsible for the translocation of the substrate across the membrane.; amino acid ABC transporter membrane-spanning permease 930359..930988 Streptococcus equi subsp. zooepidemicus MGCS10565 6762232 YP_002123258.1 CDS Sez_0887 NC_011134.1 930998 931627 D similar to ref|YP_602627.1| Histidine transport ATP-binding protein hisP [Streptococcus pyogenes MGAS10750]; Part of the binding-protein-dependent transport system for histidine. Probably responsible for energy coupling to the transport system.; amino acid transport ATP-binding protein 930998..931627 Streptococcus equi subsp. zooepidemicus MGCS10565 6762161 YP_002123259.1 CDS Sez_0888 NC_011134.1 931644 932480 D similar to gb|AAC35851.1| amino acid-binding protein Abp [Streptococcus uberis]; Probably part of a binding-protein-dependent transport system for an amino acid.; amino acid ABC transporter substrate-binding protein 931644..932480 Streptococcus equi subsp. zooepidemicus MGCS10565 6762178 YP_002123260.1 CDS Sez_0889 NC_011134.1 932591 933829 R similar to ref|YP_598703.1| Cobalt-zinc-cadmium resistance protein czcD [Streptococcus pyogenes MGAS10270]; cation efflux family protein complement(932591..933829) Streptococcus equi subsp. zooepidemicus MGCS10565 6762183 YP_002123261.1 CDS Sez_0890 NC_011134.1 933932 935266 R similar to ref|YP_060286.1| Na(+)-linked D-alanine glycine permease [Streptococcus pyogenes MGAS10394]; Na(+)-linked D-alanine glycine permease complement(933932..935266) Streptococcus equi subsp. zooepidemicus MGCS10565 6762235 YP_002123262.1 CDS pcrA NC_011134.1 935746 938043 D similar to ref|YP_060284.1| DNA helicase II [Streptococcus pyogenes MGAS10394]; Essential helicase; ATP-dependent DNA helicase UvrD 935746..938043 Streptococcus equi subsp. zooepidemicus MGCS10565 6762105 YP_002123263.1 CDS Sez_0892 NC_011134.1 938434 938694 D similar to ref|NP_269398.1| hypothetical protein SPy_1265 [Streptococcus pyogenes M1 GAS]; hypothetical protein 938434..938694 Streptococcus equi subsp. zooepidemicus MGCS10565 6762069 YP_002123264.1 CDS Sez_0893 NC_011134.1 938742 939323 D similar to ref|NP_607329.1| hypothetical protein spyM18_1215 [Streptococcus pyogenes MGAS8232]; hypothetical protein 938742..939323 Streptococcus equi subsp. zooepidemicus MGCS10565 6762046 YP_002123265.1 CDS Sez_0894 NC_011134.1 939333 939521 D similar to ref|YP_001128385.1| hypothetical protein SpyM50826 [Streptococcus pyogenes str. Manfredo]; hypothetical protein 939333..939521 Streptococcus equi subsp. zooepidemicus MGCS10565 6762021 YP_002123266.1 CDS Sez_0895 NC_011134.1 939534 940073 D similar to ref|YP_280413.1| general stress protein, Gls24 family [Streptococcus pyogenes MGAS6180]; hypothetical protein 939534..940073 Streptococcus equi subsp. zooepidemicus MGCS10565 6761963 YP_002123267.1 CDS Sez_0896 NC_011134.1 940024 940230 D similar to ref|YP_596806.1| hypothetical protein MGAS9429_Spy1075 [Streptococcus pyogenes MGAS9429]; hypothetical protein 940024..940230 Streptococcus equi subsp. zooepidemicus MGCS10565 6761821 YP_002123268.1 CDS Sez_0897 NC_011134.1 940240 940728 D similar to ref|YP_280411.1| general stress protein, Gls24 family [Streptococcus pyogenes MGAS6180]; hypothetical protein 940240..940728 Streptococcus equi subsp. zooepidemicus MGCS10565 6761847 YP_002123269.1 CDS Sez_0898 NC_011134.1 940886 941527 D similar to ref|YP_598693.1| NAD-dependent K+ or Na+ uptake system component / Transcriptional regulator, GntR family [Streptococcus pyogenes MGAS10270]; transcriptional regulator 940886..941527 Streptococcus equi subsp. zooepidemicus MGCS10565 6761839 YP_002123270.1 CDS Sez_0899 NC_011134.1 941644 942192 R similar to ref|YP_598691.1| Transcriptional regulator, TetR family [Streptococcus pyogenes MGAS10270]; TetR family transcriptional regulator complement(941644..942192) Streptococcus equi subsp. zooepidemicus MGCS10565 6761844 YP_002123271.1 CDS Sez_0900 NC_011134.1 942315 943016 D similar to ref|NP_269390.1| ABC transporter (ATP-binding protein) [Streptococcus pyogenes M1 GAS]; ABC transporter ATP-binding protein 942315..943016 Streptococcus equi subsp. zooepidemicus MGCS10565 6761712 YP_002123272.1 CDS Sez_0901 NC_011134.1 943028 945667 D similar to ref|YP_596800.1| ABC transporter permease [Streptococcus pyogenes MGAS9429]; ABC transporter permease 943028..945667 Streptococcus equi subsp. zooepidemicus MGCS10565 6761722 YP_002123273.1 CDS Sez_0902 NC_011134.1 945743 946339 D similar to ref|YP_060272.1| Type I restriction-modification system specificity subunit [Streptococcus pyogenes MGAS10394]; type I restriction- system specificity subunit 945743..946339 Streptococcus equi subsp. zooepidemicus MGCS10565 6761721 YP_002123274.1 CDS Sez_0903 NC_011134.1 946349 947311 D similar to ref|YP_602608.1| Integral membrane protein [Streptococcus pyogenes MGAS10750]; hypothetical protein 946349..947311 Streptococcus equi subsp. zooepidemicus MGCS10565 6761645 YP_002123275.1 CDS Sez_0904 NC_011134.1 947408 948745 D similar to ref|YP_001128395.1| hypothetical protein SpyM50836 [Streptococcus pyogenes str. Manfredo]; hypothetical protein 947408..948745 Streptococcus equi subsp. zooepidemicus MGCS10565 6761590 YP_002123276.1 CDS truB NC_011134.1 948854 949735 D catalyzes isomerization of specific uridines in RNA to pseudouridine; responsible for residues in T loops of many tRNAs; tRNA pseudouridine synthase B 948854..949735 Streptococcus equi subsp. zooepidemicus MGCS10565 6761464 YP_002123277.1 CDS ribC NC_011134.1 949749 950681 D catalyzes the formation of FMN from riboflavin and the formation of FAD from FMN; in Bacillus the ribC gene has both flavokinase and FAD synthetase activities; bifunctional riboflavin kinase/FMN adenylyltransferase 949749..950681 Streptococcus equi subsp. zooepidemicus MGCS10565 6761505 YP_002123278.1 CDS spxA NC_011134.1 950724 951128 D the anti-alpha factor Spx interacts with RNA polymerase alpha subunit C-terminal domain in a region that interacts with the sigma 70 subunit and may interfere with activation of promoters; in Bacillus subtilis this protein is a substrate for ClpXP protease; blocks transcription of the competence regulatory gene encoded by the srf operon; regulates a number of genes involved in thiol homeostasis including trxA and trxB; monomeric member of ArsC family of proteins; does not bind DNA; contains a disulfide bond between C10 and C13 which may sense disulfide stress; transcriptional regulator Spx 950724..951128 Streptococcus equi subsp. zooepidemicus MGCS10565 6761443 YP_002123279.1 CDS Sez_0908 NC_011134.1 951130 951408 D similar to ref|YP_060266.1| hypothetical protein M6_Spy0948 [Streptococcus pyogenes MGAS10394]; hypothetical protein 951130..951408 Streptococcus equi subsp. zooepidemicus MGCS10565 6761440 YP_002123280.1 CDS Sez_0909 NC_011134.1 951398 952174 D similar to ref|YP_060265.1| Myo-inositol-1(or 4)-monophosphatase [Streptococcus pyogenes MGAS10394]; Catalysis of the reaction: myo-inositol 1-phosphate + H2O = myo-inositol + phosphate.; myo-inositol-1(or 4)-monophosphatase 951398..952174 Streptococcus equi subsp. zooepidemicus MGCS10565 6761438 YP_002123281.1 CDS Sez_0910 NC_011134.1 952182 953498 D similar to ref|YP_596791.1| 23S rRNA m(5)C methyltransferase [Streptococcus pyogenes MGAS9429]; tRNA and rRNA cytosine-C5-methylases 952182..953498 Streptococcus equi subsp. zooepidemicus MGCS10565 6761414 YP_002123282.1 CDS Sez_0911 NC_011134.1 953636 954502 D similar to ref|NP_664685.1| phosphate ABC transporter, periplasmic phosphate-binding protein [Streptococcus pyogenes MGAS315]; Probably part of the binding-protein-dependent transport system.; ABC transporter binding protein 953636..954502 Streptococcus equi subsp. zooepidemicus MGCS10565 6761345 YP_002123283.1 CDS ptsC NC_011134.1 954513 955448 D similar to ref|YP_598678.1| Phosphate transport system permease pstC [Streptococcus pyogenes MGAS10270]; phosphate ABC transporter permease 954513..955448 Streptococcus equi subsp. zooepidemicus MGCS10565 6761381 YP_002123284.1 CDS ptsA NC_011134.1 955438 956325 D similar to ref|NP_607308.1| phosphate ABC transporter (permease) [Streptococcus pyogenes MGAS8232]; phosphate ABC transporter permease 955438..956325 Streptococcus equi subsp. zooepidemicus MGCS10565 6761359 YP_002123285.1 CDS pstB2 NC_011134.1 956342 957145 D ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation; phosphate transporter ATP-binding protein 956342..957145 Streptococcus equi subsp. zooepidemicus MGCS10565 6760871 YP_002123286.1 CDS pstB1 NC_011134.1 957156 957917 D ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation; phosphate transporter ATP-binding protein 957156..957917 Streptococcus equi subsp. zooepidemicus MGCS10565 6760869 YP_002123287.1 CDS phoU NC_011134.1 957988 958641 D similar to ref|NP_607305.1| phosphate uptake regulatory protein [Streptococcus pyogenes MGAS8232]; Not known; probably involved in phosphate transport and/or metabolism.; phosphate transport system protein PhoU 957988..958641 Streptococcus equi subsp. zooepidemicus MGCS10565 6760867 YP_002123288.1 CDS pepN NC_011134.1 958875 961412 D similar to ref|YP_598672.1| Lysyl aminopeptidase / alanine aminopeptidase [Streptococcus pyogenes MGAS10270]; Aminopeptidase with broad substrate specificity to several peptides. It has more affinity for oligopeptides than for dipeptides. It plays an essential role in the metabolism, it may be involved in nitrogen supply or protein turnover.; aminopeptidase 958875..961412 Streptococcus equi subsp. zooepidemicus MGCS10565 6760865 YP_002123289.1 CDS Sez_0918 NC_011134.1 961517 961642 D hypothetical protein 961517..961642 Streptococcus equi subsp. zooepidemicus MGCS10565 6760863 YP_002123290.1 CDS ciaR NC_011134.1 961839 962513 D similar to ref|YP_060255.1| CiaR [Streptococcus pyogenes MGAS10394]; Member of the two-component regulatory system ciaH/ciaR. Involved in early steps of competence regulation and in penicillin susceptibility.; TCS transcriptional regulatory protein ciaR 961839..962513 Streptococcus equi subsp. zooepidemicus MGCS10565 6760861 YP_002123291.1 CDS ciaH NC_011134.1 962506 963816 D similar to ref|YP_060254.1| CiaH [Streptococcus pyogenes MGAS10394]; Member of the two-component regulatory system ciaH/ciaR. Involved in early steps of competence regulation and in penicillin susceptibility. Probably phosphorylates ciaR.; TCS sensor kinase ciaH 962506..963816 Streptococcus equi subsp. zooepidemicus MGCS10565 6760856 YP_002123292.1 CDS Sez_0921 NC_011134.1 964202 964633 D similar to ref|YP_849450.1| hypothetical protein [Listeria welshimeri serovar 6b str. SLCC5334]; hypothetical protein 964202..964633 Streptococcus equi subsp. zooepidemicus MGCS10565 6760854 YP_002123293.1 CDS Sez_0922 NC_011134.1 964715 964891 D hypothetical protein 964715..964891 Streptococcus equi subsp. zooepidemicus MGCS10565 6760851 YP_002123294.1 CDS Sez_0923 NC_011134.1 965064 965447 D similar to ref|NP_734694.1| Gene info hypothetical protein gbs0224 [Streptococcus agalactiae NEM316]; hypothetical protein 965064..965447 Streptococcus equi subsp. zooepidemicus MGCS10565 6760847 YP_002123295.1 CDS Sez_0924 NC_011134.1 965444 965704 D similar to ref|YP_849451.1| hypothetical protein lwe1254 [Listeria welshimeri serovar 6b str. SLCC5334]; hypothetical protein 965444..965704 Streptococcus equi subsp. zooepidemicus MGCS10565 6760845 YP_002123296.1 CDS Sez_0925 NC_011134.1 965720 966133 D similar to ref|NP_736409.1| hypothetical protein gbs1976 [Streptococcus agalactiae NEM316]; hypothetical protein 965720..966133 Streptococcus equi subsp. zooepidemicus MGCS10565 6760842 YP_002123297.1 CDS Sez_0926 NC_011134.1 966348 966743 D similar to ref|ZP_00874490.1| hypothetical protein SsuiDRAFT_1547 [Streptococcus suis 89/1591]; hypothetical protein 966348..966743 Streptococcus equi subsp. zooepidemicus MGCS10565 6760840 YP_002123298.1 CDS Sez_0927 NC_011134.1 966743 967936 D similar to ref|NP_736400.1| hypothetical protein gbs1967 [Streptococcus agalactiae NEM316]; hypothetical protein 966743..967936 Streptococcus equi subsp. zooepidemicus MGCS10565 6760838 YP_002123299.1 CDS Sez_0928 NC_011134.1 967933 968325 D similar to ref|ZP_00874484.1| hypothetical protein SsuiDRAFT_1541 [Streptococcus suis 89/1591]; hypothetical protein 967933..968325 Streptococcus equi subsp. zooepidemicus MGCS10565 6760836 YP_002123300.1 CDS Sez_0929 NC_011134.1 968344 968628 D similar to ref|ZP_00785752.1| Unknown [Streptococcus agalactiae COH1]; hypothetical protein 968344..968628 Streptococcus equi subsp. zooepidemicus MGCS10565 6760832 YP_002123301.1 CDS rpsT NC_011134.1 968841 969083 R binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase; 30S ribosomal protein S20 complement(968841..969083) Streptococcus equi subsp. zooepidemicus MGCS10565 6760830 YP_002123302.1 CDS coaA NC_011134.1 969143 970063 R catalyzes the formation of (R)-4'-phosphopantothenate in coenzyme A biosynthesis; pantothenate kinase complement(969143..970063) Streptococcus equi subsp. zooepidemicus MGCS10565 6760828 YP_002123303.1 CDS Sez_0932 NC_011134.1 970298 970927 D similar to ref|YP_598667.1| 16S rRNA m(2)G 1207 methyltransferase [Streptococcus pyogenes MGAS10270]; Specifically methylates the guanosine in position 1207 of 16s rRNA in the 30s particle.; 16S rRNA m(2)G 1207 methyltransferase 970298..970927 Streptococcus equi subsp. zooepidemicus MGCS10565 6760826 YP_002123304.1 CDS pdp NC_011134.1 971026 972303 D Catalyzes the reversible phosphorolysis of pyrimidines in the nucleotide synthesis salvage pathway; pyrimidine-nucleoside phosphorylase 971026..972303 Streptococcus equi subsp. zooepidemicus MGCS10565 6760822 YP_002123305.1 CDS deoC NC_011134.1 972317 972979 D catalyzes the formation of D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-D-ribose-5-phosphate; deoxyribose-phosphate aldolase 972317..972979 Streptococcus equi subsp. zooepidemicus MGCS10565 6760820 YP_002123306.1 CDS cdd NC_011134.1 972966 973355 D Reclaims exogenous and endogenous cytidine and 2'-deoxycytidine molecules for UMP synthesis; cytidine deaminase 972966..973355 Streptococcus equi subsp. zooepidemicus MGCS10565 6760817 YP_002123307.1 CDS Sez_0936 NC_011134.1 973446 974498 D similar to ref|YP_280382.1| nucleoside-binding protein [Streptococcus pyogenes MGAS6180]; ABC transporter substrate-binding lipoprotein 973446..974498 Streptococcus equi subsp. zooepidemicus MGCS10565 6760813 YP_002123308.1 CDS Sez_0937 NC_011134.1 974625 976157 D similar to ref|ZP_00365738.1| COG3845: ABC-type uncharacterized transport systems, ATPase components [Streptococcus pyogenes M49 591]; Part of the binding-protein-dependent transport system for nucleosides. Probably responsible for energy coupling to the transport system.; nucleoside transport ATP-binding protein 974625..976157 Streptococcus equi subsp. zooepidemicus MGCS10565 6760811 YP_002123309.1 CDS Sez_0938 NC_011134.1 976150 977214 D similar to ref|YP_280380.1| nucleoside transport system permease [Streptococcus pyogenes MGAS6180]; ABC transporter permease 976150..977214 Streptococcus equi subsp. zooepidemicus MGCS10565 6760809 YP_002123310.1 CDS Sez_0939 NC_011134.1 977216 978172 D similar to ref|YP_060246.1| Nucleoside transport system permease [Streptococcus pyogenes MGAS10394]; ABC transporter permease 977216..978172 Streptococcus equi subsp. zooepidemicus MGCS10565 6760804 YP_002123311.1 CDS Sez_0940 NC_011134.1 978210 978332 R hypothetical protein complement(978210..978332) Streptococcus equi subsp. zooepidemicus MGCS10565 6760802 YP_002123312.1 CDS pgmA NC_011134.1 978605 980353 R similar to ref|YP_001128419.1| phosphomannomutase [Streptococcus pyogenes str. Manfredo]; phosphomannomutase complement(978605..980353) Streptococcus equi subsp. zooepidemicus MGCS10565 6760800 YP_002123313.1 CDS Sez_0942 NC_011134.1 980499 981071 R similar to ref|YP_280377.1| transporter [Streptococcus pyogenes MGAS6180]; pantothenate transporter complement(980499..981071) Streptococcus equi subsp. zooepidemicus MGCS10565 6760798 YP_002123314.1 CDS coaC NC_011134.1 981127 981672 R decarboxylates 4-phosphopantothenoylcysteine to form 4'-phosphopantotheine.; phosphopantothenoylcysteine decarboxylase complement(981127..981672) Streptococcus equi subsp. zooepidemicus MGCS10565 6760796 YP_002123315.1 CDS coaBC NC_011134.1 981665 982357 R similar to ref|YP_596769.1| phosphopantothenate--cysteine ligase [Streptococcus pyogenes MGAS9429]; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.; phosphopantothenate--cysteine ligase complement(981665..982357) Streptococcus equi subsp. zooepidemicus MGCS10565 6760794 YP_002123316.1 CDS fhs1 NC_011134.1 982555 984225 D catalyzes the formation of 10-formyltetrahydrofolate from formate and tetrahydrofolate; formate--tetrahydrofolate ligase 982555..984225 Streptococcus equi subsp. zooepidemicus MGCS10565 6760791 YP_002123317.1 CDS scpZ NC_011134.1 984524 987895 D similar to ref|ZP_00781360.1| streptococcal C5a peptidase [Streptococcus agalactiae 18RS21]; This virulence factor of S.pyogenes specifically cleaves the human serum chemotaxin C5a at 68-Lys-|-Asp-69 bond near its C- terminus, destroying its ability to serve as a chemoattractant, in GAS it sets in the MGA regulon.; C5a peptidase precursor ScpZ 984524..987895 Streptococcus equi subsp. zooepidemicus MGCS10565 6760789 YP_002123318.1 CDS cls NC_011134.1 988019 989686 D similar to ref|NP_607281.1| cardiolipin synthetase [Streptococcus pyogenes MGAS8232]; Catalyzes The Reversible Phosphatidyl Group Transfer From One Phosphatidylglycerol Molecule To Another To Form Cardiolipin (Cl) (Diphosphatidylglycerol) And Glycerol. Affects Resistance To The Gyrase Inhibitor Novobiocin.; cardiolipin synthetase Cls 988019..989686 Streptococcus equi subsp. zooepidemicus MGCS10565 6760787 YP_002123319.1 CDS asd NC_011134.1 990103 991191 D catalyzes the formation of 4-aspartyl phosphate from aspartate 4-semialdehyde; aspartate-semialdehyde dehydrogenase 990103..991191 Streptococcus equi subsp. zooepidemicus MGCS10565 6760784 YP_002123320.1 CDS nrdD NC_011134.1 991291 991629 D similar to ref|NP_664655.1| anaerobic ribonucleotide reductase [Streptococcus pyogenes MGAS315]; anaerobic ribonucleoside triphosphate reductase NrdD 991291..991629 Streptococcus equi subsp. zooepidemicus MGCS10565 6760782 YP_002123321.1 CDS Sez_0950 NC_011134.1 991665 992948 R similar to ref|YP_001128433.1| GntR family regulatory protein [Streptococcus pyogenes str. Manfredo]; GntR family transcriptional regulator complement(991665..992948) Streptococcus equi subsp. zooepidemicus MGCS10565 6760779 YP_002123322.1 CDS Sez_0951 NC_011134.1 993028 993897 D catalyzes the formation of pyridoxal 5'-phosphate from pyridoxal; pyridoxamine kinase 993028..993897 Streptococcus equi subsp. zooepidemicus MGCS10565 6760776 YP_002123323.1 CDS Sez_0952 NC_011134.1 993890 994435 D similar to emb|CAM30204.1| membrane protein [Streptococcus pyogenes str. Manfredo]; hypothetical protein 993890..994435 Streptococcus equi subsp. zooepidemicus MGCS10565 6760774 YP_002123324.1 CDS Sez_0953 NC_011134.1 994912 995061 R hypothetical protein complement(994912..995061) Streptococcus equi subsp. zooepidemicus MGCS10565 6760772 YP_002123325.1 CDS Sez_0954 NC_011134.1 995070 996656 D similar to ref|YP_280361.1| ABC transporter ATP-binding protein [Streptococcus pyogenes MGAS6180]; ABC transporter 995070..996656 Streptococcus equi subsp. zooepidemicus MGCS10565 6760770 YP_002123326.1 CDS Sez_0955 NC_011134.1 997096 998049 D similar to ref|YP_138591.1| IS1239 transposase [Streptococcus thermophilus LMG 18311]; transposase IS1239 997096..998049 Streptococcus equi subsp. zooepidemicus MGCS10565 6760768 YP_002123327.1 CDS Sez_0956 NC_011134.1 998162 998419 D similar to ref|YP_596727.1| hypothetical protein MGAS9429_Spy0996 [Streptococcus pyogenes MGAS9429]; hypothetical protein 998162..998419 Streptococcus equi subsp. zooepidemicus MGCS10565 6760766 YP_002123328.1 CDS Sez_0957 NC_011134.1 998587 999717 R similar to ref|YP_596508.1| transposase [Streptococcus pyogenes MGAS9429]; transposase IS1548-like complement(998587..999717) Streptococcus equi subsp. zooepidemicus MGCS10565 6760764 YP_002123329.1 CDS Sez_0958 NC_011134.1 1000065 1000970 R similar to ref|YP_596728.1| diacylglycerol kinase family protein [Streptococcus pyogenes MGAS9429]; transcriptional regulator complement(1000065..1000970) Streptococcus equi subsp. zooepidemicus MGCS10565 6760762 YP_002123330.1 CDS hylIII NC_011134.1 1001080 1001730 R similar to ref|NP_269309.1| hemolysin III [Streptococcus pyogenes M1 GAS]; Unknown, possible extracellur hemolysin but lacks a SrtA secretion signal peptide.; hemolysin III HylIII complement(1001080..1001730) Streptococcus equi subsp. zooepidemicus MGCS10565 6760760 YP_002123331.1 CDS Sez_0960 NC_011134.1 1001714 1002169 R similar to ref|NP_607242.1| hypothetical protein spyM18_1120 [Streptococcus pyogenes MGAS8232]; hypothetical protein complement(1001714..1002169) Streptococcus equi subsp. zooepidemicus MGCS10565 6760757 YP_002123332.1 CDS Sez_0961 NC_011134.1 1002429 1003184 D similar to ref|YP_329155.1| hypothetical protein SAK_0522 [Streptococcus agalactiae A909]; ubiquinone/menaquinone biosynthesis methyltransferase UbiE/COQ5 1002429..1003184 Streptococcus equi subsp. zooepidemicus MGCS10565 6760755 YP_002123333.1 CDS Sez_0962 NC_011134.1 1003212 1003550 D similar to ref|NP_721671.1| hypothetical protein SMU.1300c [Streptococcus mutans UA159]; hypothetical protein 1003212..1003550 Streptococcus equi subsp. zooepidemicus MGCS10565 6760753 YP_002123334.1 CDS Sez_0963 NC_011134.1 1003552 1003857 D similar to ref|NP_607650.1| acetate kinase [Streptococcus pyogenes MGAS8232]; Catalysis of the reaction: ATP + acetate = ADP + acetyl phosphate.; acetate kinase 1003552..1003857 Streptococcus equi subsp. zooepidemicus MGCS10565 6760751 YP_002123335.1 CDS Sez_0964 NC_011134.1 1004615 1005352 D similar to ref|NP_606739.1| response regulator [Streptococcus pyogenes MGAS8232]; Required for high-level post-exponential phase expression of a series of secreted proteins, has similarity with BlpR/FasA/SilA regulators.; accessory gene regulator protein A, response regulator FasA or ComE or BlpR 1004615..1005352 Streptococcus equi subsp. zooepidemicus MGCS10565 6760749 YP_002123336.1 CDS Sez_0965 NC_011134.1 1005725 1005925 D similar to ref|YP_281761.1| bacteriocin [Streptococcus pyogenes MGAS5005]; bacteriocin 1005725..1005925 Streptococcus equi subsp. zooepidemicus MGCS10565 6760747 YP_002123337.1 CDS Sez_0966 NC_011134.1 1005992 1006846 D similar to ref|NP_688943.1| ABC transporter, ATP-binding protein [Streptococcus agalactiae 2603V/R]; ABC transporter 1005992..1006846 Streptococcus equi subsp. zooepidemicus MGCS10565 6760745 YP_002123338.1 CDS Sez_0967 NC_011134.1 1006852 1007331 D similar to ref|ZP_00789085.1| membrane protein [Streptococcus agalactiae 515]; Unknown, predicted to be Sec-indepently secreted by SecretomeP 2.0; hypothetical protein 1006852..1007331 Streptococcus equi subsp. zooepidemicus MGCS10565 6760743 YP_002123339.1 CDS Sez_0968 NC_011134.1 1007358 1008014 D similar to ref|YP_330508.1| hypothetical protein SAK_1913 [Streptococcus agalactiae A909]; hypothetical protein 1007358..1008014 Streptococcus equi subsp. zooepidemicus MGCS10565 6760741 YP_002123340.1 CDS Sez_0969 NC_011134.1 1008276 1008506 D similar to ref|YP_140101.1| pore-forming peptide, bacteriocin [Streptococcus thermophilus LMG 18311]; bacteriocin 1008276..1008506 Streptococcus equi subsp. zooepidemicus MGCS10565 6760739 YP_002123341.1 CDS Sez_0970 NC_011134.1 1009299 1010150 D similar to ref|YP_140093.1| immunity/modification protein [Streptococcus thermophilus LMG 18311]; immunity modification protein 1009299..1010150 Streptococcus equi subsp. zooepidemicus MGCS10565 6760737 YP_002123342.1 CDS Sez_0971 NC_011134.1 1010629 1010910 D similar to ref|ZP_01835892.1| hypothetical protein CGSSp23BS72_00905 [Streptococcus pneumoniae SP23-BS72]; hypothetical protein 1010629..1010910 Streptococcus equi subsp. zooepidemicus MGCS10565 6760734 YP_002123343.1 CDS Sez_0972 NC_011134.1 1011015 1013030 D similar to ref|ZP_01835893.1| hypothetical protein CGSSp23BS72_00910 [Streptococcus pneumoniae SP23-BS72]; immunity protein, bacteriocin-associated integral membrane protein subfamily 1011015..1013030 Streptococcus equi subsp. zooepidemicus MGCS10565 6760732 YP_002123344.1 CDS Sez_0973 NC_011134.1 1013032 1013664 D similar to ref|ZP_01821399.1| competence damage-inducible protein A [Streptococcus pneumoniae SP6-BS73]; ABC transporter 1013032..1013664 Streptococcus equi subsp. zooepidemicus MGCS10565 6760730 YP_002123345.1 CDS rbgA NC_011134.1 1014676 1015530 D essential GTPase; functions in ribosome assembly; binds a unique part of the 23S rRNA; interacts with ribosomal protein L25(Ctc); ribosomal biogenesis GTPase 1014676..1015530 Streptococcus equi subsp. zooepidemicus MGCS10565 6760728 YP_002123346.1 CDS rnhB NC_011134.1 1015511 1016293 D RNH2; RNase HII; binds manganese; endonuclease which specifically degrades the RNA of RNA-DNA hybrids; ribonuclease HII 1015511..1016293 Streptococcus equi subsp. zooepidemicus MGCS10565 6760726 YP_002123347.1 CDS smf NC_011134.1 1016549 1017394 D similar to ref|YP_598607.1| DNA processing protein [Streptococcus pyogenes MGAS10270]; nucleotide-binding protein Smf 1016549..1017394 Streptococcus equi subsp. zooepidemicus MGCS10565 6760724 YP_002123348.1 CDS topA NC_011134.1 1017486 1019627 D catalyzes the ATP-dependent breakage of single-stranded DNA followed by passage and rejoining, maintains net negative superhelicity; DNA topoisomerase I 1017486..1019627 Streptococcus equi subsp. zooepidemicus MGCS10565 6760721 YP_002123349.1 CDS satD NC_011134.1 1019715 1020389 D similar to ref|YP_602534.1| hypothetical protein MGAS10750_Spy1040 [Streptococcus pyogenes MGAS10750]; secretion and acid tolerance protein SatD 1019715..1020389 Streptococcus equi subsp. zooepidemicus MGCS10565 6760719 YP_002123350.1 CDS satE NC_011134.1 1020410 1021123 D similar to ref|ZP_00366032.1| COG4988: ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components [Streptococcus pyogenes M49 591]; secretion and acid tolerance protein SatE 1020410..1021123 Streptococcus equi subsp. zooepidemicus MGCS10565 6760716 YP_002123351.1 CDS Sez_0980 NC_011134.1 1021540 1023261 D similar to ref|ZP_01371554.1| transposase, IS4 [Desulfitobacterium hafniense DCB-2]; transposase IS4-like 1021540..1023261 Streptococcus equi subsp. zooepidemicus MGCS10565 6760713 YP_002123352.1 CDS citC NC_011134.1 1024453 1025502 R similar to ref|YP_598633.1| (Citrate (pro-3S)-lyase) ligase [Streptococcus pyogenes MGAS10270]; Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase.; [citrate (pro-3S)-lyase] ligase complement(1024453..1025502) Streptococcus equi subsp. zooepidemicus MGCS10565 6760708 YP_002123353.1 CDS Sez_0984 NC_011134.1 1025677 1025826 D similar to ref|YP_602540.1| Na+ transporting oxaloacetate decarboxylase beta chain [Streptococcus pyogenes MGAS10750]; bifunctional oxaloacetate decarboxylase subunit beta/methylmalonyl-CoA decarboxylase subunit beta 1025677..1025826 Streptococcus equi subsp. zooepidemicus MGCS10565 6760706 YP_002123354.1 CDS Sez_0985 NC_011134.1 1025961 1027157 D similar to ref|NP_603429.1| Hypothetical membrane-spanning protein [Fusobacterium nucleatum subsp. nucleatum ATCC 25586]; ammonia monooxygenase 1025961..1027157 Streptococcus equi subsp. zooepidemicus MGCS10565 6760704 YP_002123355.1 CDS citG NC_011134.1 1027243 1028127 R similar to ref|NP_664630.1| CitG protein,2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase [Streptococcus pyogenes MGAS315]; Catalyzes the formation of 2-(5''-triphosphoribosyl)-3'- dephosphocoenzyme-A, the precursor of the prosthetic group of the holo-acyl carrier protein (gamma chain) of citrate lyase, from ATP and dephospho-CoA.; 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase complement(1027243..1028127) Streptococcus equi subsp. zooepidemicus MGCS10565 6760702 YP_002123356.1 CDS Sez_0987 NC_011134.1 1028120 1028815 R similar to ref|YP_602542.1| Transcriptional regulator, GntR family [Streptococcus pyogenes MGAS10750]; GntR family transcriptional regulator complement(1028120..1028815) Streptococcus equi subsp. zooepidemicus MGCS10565 6760699 YP_002123357.1 CDS citN NC_011134.1 1028968 1030371 R similar to ref|YP_060207.1| Mg2+/citrate complex secondary transporter [Streptococcus pyogenes MGAS10394]; Transports the free citrate anion. Probably cotransports citrate and at least three or four protons. The citrate uptake is inhibited by the presence of magnesium ions.; Mg2+/citrate complex transporter complement(1028968..1030371) Streptococcus equi subsp. zooepidemicus MGCS10565 6760697 YP_002123358.1 CDS Sez_0989 NC_011134.1 1030410 1030616 D hypothetical protein 1030410..1030616 Streptococcus equi subsp. zooepidemicus MGCS10565 6760694 YP_002123359.1 CDS Sez_0990 NC_011134.1 1030753 1031097 D similar to ref|NP_607255.1| hypothetical protein spyM18_1133 [Streptococcus pyogenes MGAS8232]; hypothetical protein 1030753..1031097 Streptococcus equi subsp. zooepidemicus MGCS10565 6760692 YP_002123360.1 CDS bcc NC_011134.1 1031115 1031501 D composes the biotin carboxyl carrier protein subunit of the acetyl-CoA carboxylase complex, the enzyme that catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, which in turn controls the rate of fatty acid metabolism; acetyl-CoA carboxylase biotin carboxyl carrier protein subunit 1031115..1031501 Streptococcus equi subsp. zooepidemicus MGCS10565 6760689 YP_002123361.1 CDS oadB NC_011134.1 1031552 1032673 D similar to ref|YP_280344.1| oxaloacetate decarboxylase beta chain [Streptococcus pyogenes MGAS6180]; Lyase and sodium transporter.; oxaloacetate decarboxylase subunit beta OadB 1031552..1032673 Streptococcus equi subsp. zooepidemicus MGCS10565 6760687 YP_002123362.1 CDS Sez_0993 NC_011134.1 1032688 1032822 D similar to ref|YP_060211.1| hypothetical protein M6_Spy0893 [Streptococcus pyogenes MGAS10394]; hypothetical protein 1032688..1032822 Streptococcus equi subsp. zooepidemicus MGCS10565 6760684 YP_002123363.1 CDS citD NC_011134.1 1032855 1033163 D acyl carrier protein; with CitE and CitF catalyzes the formation of oxaloacetate from citrate; citrate lyase subunit gamma 1032855..1033163 Streptococcus equi subsp. zooepidemicus MGCS10565 6760682 YP_002123364.1 CDS citE NC_011134.1 1033175 1034038 D similar to ref|YP_598629.1| Citrate lyase beta chain / Citryl-CoA lyase subunit [Streptococcus pyogenes MGAS10270]; citrate lyase subunit beta CitE 1033175..1034038 Streptococcus equi subsp. zooepidemicus MGCS10565 6760677 YP_002123365.1 CDS citF NC_011134.1 1034040 1035572 D similar to ref|YP_001128449.1| citrate lyase alpha subunit [Streptococcus pyogenes str. Manfredo]; citrate lyase subunit alpha CitF 1034040..1035572 Streptococcus equi subsp. zooepidemicus MGCS10565 6760675 YP_002123366.1 CDS citX NC_011134.1 1035565 1036125 D 2'-(5''-phosphoribosyl)-3'-dephospho-CoA transferase; holo-citrate lyase synthase; CitG forms the prosthetic group precursor 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA which is then transferred to apo-ACP by CitX to produce holo-ACP and pyrophosphate; 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase 1035565..1036125 Streptococcus equi subsp. zooepidemicus MGCS10565 6760673 YP_002123367.1 CDS Sez_1000 NC_011134.1 1037812 1038171 R similar to ref|NP_607265.1| hypothetical protein spyM18_1144 [Streptococcus pyogenes MGAS8232]; hypothetical protein complement(1037812..1038171) Streptococcus equi subsp. zooepidemicus MGCS10565 6760669 YP_002123368.1 CDS Sez_1001 NC_011134.1 1038172 1038309 D hypothetical protein 1038172..1038309 Streptococcus equi subsp. zooepidemicus MGCS10565 6760667 YP_002123369.1 CDS Sez_1002 NC_011134.1 1038621 1039373 D similar to dbj|BAB83943.1| mutans bacitracin-resistance related protein A [Streptococcus mutans]; Part of the ABC transporter complex which could be involved in peptide resistance. Responsible for energy coupling to the transport system ().; ABC transporter ATP-binding protein 1038621..1039373 Streptococcus equi subsp. zooepidemicus MGCS10565 6760665 YP_002123370.1 CDS bceB NC_011134.1 1039376 1041331 D similar to ref|NP_687986.1| ABC transporter, permease, [Streptococcus agalactiae 2603V/R]; Part of the ABC transporter complex bceAB (TC 3.A.1.123.5) involved in bacitracin export.; bacitracin export permease BceB 1039376..1041331 Streptococcus equi subsp. zooepidemicus MGCS10565 6760662 YP_002123371.1 CDS bceR NC_011134.1 1041375 1042040 D similar to ref|NP_687987.1| DNA-binding response regulator [Streptococcus agalactiae 2603V/R]; Member of the two-component regulatory system bceS/bceR involved in the regulation of bacitracin resistance. When activated by bceS, binds to the upstream region of the bceAB promoter and up-regulates the expression of these two genes.; TCS response regulator BceR 1041375..1042040 Streptococcus equi subsp. zooepidemicus MGCS10565 6760660 YP_002123372.1 CDS bceS NC_011134.1 1042037 1043014 D similar to ref|NP_721404.1| histidine kinase [Streptococcus mutans UA159]; Signal transduction histidine kinase; TCS senso kinase BceS 1042037..1043014 Streptococcus equi subsp. zooepidemicus MGCS10565 6760658 YP_002123373.1 CDS xerS NC_011134.1 1043152 1044222 R site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; cell division protein FtsK may regulate the XerS; site-specific tyrosine recombinase XerS complement(1043152..1044222) Streptococcus equi subsp. zooepidemicus MGCS10565 6760655 YP_002123374.1 CDS Sez_1007 NC_011134.1 1044374 1044811 R similar to ref|NP_687863.1| GtrA family protein [Streptococcus agalactiae 2603V/R]; Unknown. GtrA is predicted to be an integral membrane protein with 4 transmembrane spans. It is involved is in O antigen modification by Shigella flexneri bacteriophage X (SfX), but does not determine the specificity of glucosylation. Its function remains unknown, but it may play a role in translocation of UDP phosphate linked glucose (UndP-Glc) across the cytoplasmic membrane.; GtrA family protein complement(1044374..1044811) Streptococcus equi subsp. zooepidemicus MGCS10565 6760653 YP_002123375.1 CDS Sez_1008 NC_011134.1 1045006 1045704 D similar to ref|YP_598637.1| phage transcriptional repressor [Streptococcus pyogenes MGAS10270]; Phage transcriptional repressor 1045006..1045704 Streptococcus equi subsp. zooepidemicus MGCS10565 6760651 YP_002123376.1 CDS Sez_1009 NC_011134.1 1046056 1046850 R similar to ref|ZP_02075633.1| hypothetical protein CLOL250_02409 [Clostridium sp. L2-50]; hypothetical protein complement(1046056..1046850) Streptococcus equi subsp. zooepidemicus MGCS10565 6760649 YP_002123377.1 CDS guaA NC_011134.1 1047063 1048610 R contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway; GMP synthase complement(1047063..1048610) Streptococcus equi subsp. zooepidemicus MGCS10565 6760647 YP_002123378.1 CDS Sez_1011 NC_011134.1 1048756 1048926 R hypothetical protein complement(1048756..1048926) Streptococcus equi subsp. zooepidemicus MGCS10565 6760645 YP_002123379.1 CDS Sez_1012 NC_011134.1 1048900 1049598 D similar to ref|ZP_00366165.1| COG2188: Transcriptional regulators [Streptococcus pyogenes M49 591]; GntR family transcriptional regulator 1048900..1049598 Streptococcus equi subsp. zooepidemicus MGCS10565 6760643 YP_002123380.1 CDS Sez_1013 NC_011134.1 1049801 1050142 D similar to ref|NP_269340.1| hypothetical protein SPy_1201 [Streptococcus pyogenes M1 GAS]; Not known. Could take part in the signal recognition particle (SRP) pathway. This is inferred due to the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein.; DNA-binding protein 1049801..1050142 Streptococcus equi subsp. zooepidemicus MGCS10565 6760641 YP_002123381.1 CDS ffh NC_011134.1 1050157 1051728 D similar to ref|YP_282278.1| signal recognition particle, subunit FFH/SRP54 [Streptococcus pyogenes MGAS5005]; Necessary for efficient export of extra-cytoplasmic proteins. Binds to the signal sequence when it emerges from the ribosomes.; signal recognition particle protein Ffh 1050157..1051728 Streptococcus equi subsp. zooepidemicus MGCS10565 6760639 YP_002123382.1 CDS murM NC_011134.1 1051881 1053107 R similar to ref|YP_060227.1| UDP-N-acetylmuramoylpentapeptide-lysine N(6)-alanyltransferase [Streptococcus pyogenes MGAS10394]; UDP-N-acetylmuramoylpentapeptide-lysine N(6)-alanyltransferase MurM complement(1051881..1053107) Streptococcus equi subsp. zooepidemicus MGCS10565 6760637 YP_002123383.1 CDS Sez_1016 NC_011134.1 1053329 1054300 R similar to ref|ZP_00780941.1| extracellular protein [Streptococcus agalactiae 18RS21]; hypothetical protein complement(1053329..1054300) Streptococcus equi subsp. zooepidemicus MGCS10565 6760635 YP_002123384.1 CDS htpA NC_011134.1 1054613 1055053 R similar to ref|ZP_01823706.1| histidine triad protein [Streptococcus pneumoniae SP9-BS68]; histidine triad protein HtpA complement(1054613..1055053) Streptococcus equi subsp. zooepidemicus MGCS10565 6760899 YP_002123385.1 CDS lmb NC_011134.1 1055050 1055991 R similar to emb|CAC85395.1| laminin binding protein [Streptococcus dysgalactiae subsp. equisimilis]; laminin-binding surface protein Lmb complement(1055050..1055991) Streptococcus equi subsp. zooepidemicus MGCS10565 6760435 YP_002123386.1 CDS Sez_1019 NC_011134.1 1056421 1056888 R similar to ref|NP_687974.1| glyoxylase family protein [Streptococcus agalactiae 2603V/R]; Catalysis of the reaction: (R)-S-lactoylglutathione = glutathione + methylglyoxal.; lactoylglutathione lyase complement(1056421..1056888) Streptococcus equi subsp. zooepidemicus MGCS10565 6760433 YP_002123387.1 CDS srtA NC_011134.1 1056932 1057645 R similar to ref|YP_598598.1| Sortase [Streptococcus pyogenes MGAS10270]; Transpeptidation reaction linking surface proteins to peptidoglycan.; A family sortase SrtA complement(1056932..1057645) Streptococcus equi subsp. zooepidemicus MGCS10565 6760431 YP_002123388.1 CDS gyrA NC_011134.1 1057692 1060187 R negatively supercoils closed circular double-stranded DNA; DNA gyrase subunit A complement(1057692..1060187) Streptococcus equi subsp. zooepidemicus MGCS10565 6760427 YP_002123389.1 CDS ldh NC_011134.1 1060379 1061362 D Converts (S)-lactate and NAD(+) to pyruvate and NADH; L-lactate dehydrogenase 1060379..1061362 Streptococcus equi subsp. zooepidemicus MGCS10565 6760425 YP_002123390.1 CDS nox NC_011134.1 1061583 1062893 R similar to gb|AAL78063.1| NADH oxidase [Streptococcus equi subsp. zooepidemicus]; Catalyzes the four-electron reduction of molecular oxygen to water.; NADH oxidase H2O-forming Nox complement(1061583..1062893) Streptococcus equi subsp. zooepidemicus MGCS10565 6760423 YP_002123391.1 CDS pvaA NC_011134.1 1063200 1063802 R similar to ref|YP_598592.1| antigen-like protein [Streptococcus pyogenes MGAS10270]; COG0741: Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains).; pneumococcal vaccine antigen A-like protein PvaA complement(1063200..1063802) Streptococcus equi subsp. zooepidemicus MGCS10565 6760421 YP_002123392.1 CDS Sez_1025 NC_011134.1 1063803 1064780 R similar to ref|YP_598591.1| hypothetical protein MGAS10270_Spy0982 [Streptococcus pyogenes MGAS10270]; hypothetical protein complement(1063803..1064780) Streptococcus equi subsp. zooepidemicus MGCS10565 6760419 YP_002123393.1 CDS glyA NC_011134.1 1064783 1066042 R catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate; serine hydroxymethyltransferase complement(1064783..1066042) Streptococcus equi subsp. zooepidemicus MGCS10565 6760412 YP_002123394.1 CDS phnO NC_011134.1 1066054 1066485 R similar to ref|ZP_00366378.1| COG0454: Histone acetyltransferase HPA2 and related acetyltransferases [Streptococcus pyogenes M49 591]; phosphinothricin N-acetyltransferase PhnO complement(1066054..1066485) Streptococcus equi subsp. zooepidemicus MGCS10565 6760409 YP_002123395.1 CDS Sez_1028 NC_011134.1 1066499 1067092 R similar to ref|ZP_00366379.1| COG0009: translation factor (SUA5) [Streptococcus pyogenes M49 591]; Sua5/YciO/YrdC/YwlC family protein complement(1066499..1067092) Streptococcus equi subsp. zooepidemicus MGCS10565 6760407 YP_002123396.1 CDS Sez_1029 NC_011134.1 1067064 1067912 R similar to ref|YP_001128483.1| methyltransferase [Streptococcus pyogenes str. Manfredo]; Methylates The Translation Termination Release Factor Rf1 On Gln-235 And Rf2 On Gln-252.; polypeptide chain release factor methylase complement(1067064..1067912) Streptococcus equi subsp. zooepidemicus MGCS10565 6760405 YP_002123397.1 CDS prfA NC_011134.1 1067909 1068991 R recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2; peptide chain release factor 1 complement(1067909..1068991) Streptococcus equi subsp. zooepidemicus MGCS10565 6760403 YP_002123398.1 CDS tdk NC_011134.1 1069033 1069602 R similar to ref|NP_269291.1| thymidine kinase [Streptococcus pyogenes M1 GAS]; Phosphorylates Both Thymidine And Deoxyuridine.; thymidine kinase Tdk complement(1069033..1069602) Streptococcus equi subsp. zooepidemicus MGCS10565 6760401 YP_002123399.1 CDS Sez_1032 NC_011134.1 1069594 1069806 D hypothetical protein 1069594..1069806 Streptococcus equi subsp. zooepidemicus MGCS10565 6760399 YP_002123400.1 CDS Sez_1033 NC_011134.1 1069787 1069972 D 4-OT; member of subfamily 5; forms a dimer; the function in the Escherichia coli cell is unknown; 4-oxalocrotonate tautomerase 1069787..1069972 Streptococcus equi subsp. zooepidemicus MGCS10565 6760397 YP_002123401.1 CDS apbE NC_011134.1 1070027 1070968 D similar to ref|YP_598583.1| Iron-sulfur cluster assembly/repair protein ApbE [Streptococcus pyogenes MGAS10270]; Involved in the conversion of aminoimidazole ribotide (AIR), a purine intermediate, to the 4-amino-5-hydroxymethyl-2- methyl pyrimidine (HMP) moiety of thiamine.; thiamin biosynthesis lipoprotein ApbE 1070027..1070968 Streptococcus equi subsp. zooepidemicus MGCS10565 6760395 YP_002123402.1 CDS xpt NC_011134.1 1071243 1071827 R Catalyzes the transfer of the phosphoribosyl moiety from 5-phospho--D-ribosyl-1-pyrophosphate (PRib-PP) to the 6-oxo-guanine and -xanthine; xanthine phosphoribosyltransferase complement(1071243..1071827) Streptococcus equi subsp. zooepidemicus MGCS10565 6760392 YP_002123403.1 CDS guaC NC_011134.1 1072010 1072996 R similar to ref|ZP_00365512.1| COG0516: IMP dehydrogenase/GMP reductase [Streptococcus pyogenes M49 591]; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.; guanosine 5'-monophosphate oxidoreductase complement(1072010..1072996) Streptococcus equi subsp. zooepidemicus MGCS10565 6760970 YP_002123404.1 CDS opuCB NC_011134.1 1073352 1074869 R similar to ref|YP_598579.1| Glycine betaine transport system permease / Glycine betaine-binding protein [Streptococcus pyogenes MGAS10270]; Involved in a high affinity multicomponent binding- protein-dependent transport system for glycine betaine, carnitine and choline; probably responsible for the translocation of the substrate across the membrane.; glycine betaine/carnitine/choline transport system permease OpuCB complement(1073352..1074869) Streptococcus equi subsp. zooepidemicus MGCS10565 6760389 YP_002123405.1 CDS opuCA NC_011134.1 1074877 1075605 R similar to ref|NP_664595.1| ABC transporter (ATP-binding protein) [Streptococcus pyogenes MGAS315]; Involved in a high affinity multicomponent binding- protein-dependent transport system for glycine betaine, carnitine and choline; probably responsible for energy coupling to the transport system.; glycine betaine/carnitine/choline transport ATP-binding protein OpuCA complement(1074877..1075605) Streptococcus equi subsp. zooepidemicus MGCS10565 6760387 YP_002123406.1 CDS Sez_1039 NC_011134.1 1075860 1076546 D similar to ref|YP_602497.1| Na+ driven multidrug efflux pump [Streptococcus pyogenes MGAS10750]; Na+ driven multidrug efflux pump 1075860..1076546 Streptococcus equi subsp. zooepidemicus MGCS10565 6760385 YP_002123407.1 CDS Sez_1040 NC_011134.1 1076651 1077421 R similar to ref|YP_280295.1| short chain dehydrogenase [Streptococcus pyogenes MGAS6180]; Catalyzes the NADP-dependent oxidation of L-allo- threonine and L-serine.; NADP-dependent L-serine/L-allo-threonine dehydrogenase complement(1076651..1077421) Streptococcus equi subsp. zooepidemicus MGCS10565 6760383 YP_002123408.1 CDS yjbO NC_011134.1 1078522 1079418 R similar to ref|NP_664590.1| ribosomal large subunit pseudouridine synthase [Streptococcus pyogenes MGAS315]; Responsible For Synthesis Of Pseudouridine From Uracil At Positions 1911, 1915 And 1917 In 23s Ribosomal RNA; similar to Bacillus subtilis YjbO type; ribosomal large subunit pseudouridine synthase D complement(1078522..1079418) Streptococcus equi subsp. zooepidemicus MGCS10565 6760381 YP_002123409.1 CDS ppnK NC_011134.1 1079415 1080242 R catalyzes the phosphorylation of NAD to NADP; inorganic polyphosphate/ATP-NAD kinase complement(1079415..1080242) Streptococcus equi subsp. zooepidemicus MGCS10565 6760378 YP_002123410.1 CDS relA NC_011134.1 1080226 1080897 R similar to ref|NP_269279.1| GTP pyrophosphokinase [Streptococcus pyogenes M1 GAS]; In eubacteria ppGpp (guanosine 3'-diphosphate 5-'diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. This enzyme catalyzes the formation of pppGpp which is then hydrolyzed to form ppGpp.; GTP pyrophosphokinase complement(1080226..1080897) Streptococcus equi subsp. zooepidemicus MGCS10565 6760375 YP_002123411.1 CDS Sez_1046 NC_011134.1 1080992 1081564 D similar to ref|YP_282209.1| adenylate cyclase family [Streptococcus pyogenes MGAS5005]; adenylate cyclase 1080992..1081564 Streptococcus equi subsp. zooepidemicus MGCS10565 6761071 YP_002123412.1 CDS prs NC_011134.1 1081699 1082673 D catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP; ribose-phosphate pyrophosphokinase 1081699..1082673 Streptococcus equi subsp. zooepidemicus MGCS10565 6761182 YP_002123413.1 CDS iscS NC_011134.1 1082676 1083803 D similar to ref|YP_001128501.1| cysteine desulfurase [Streptococcus pyogenes str. Manfredo]; Catalyzes the removal of elemental sulfur from cysteine to produce alanine.; cysteine desulfurase IscS 1082676..1083803 Streptococcus equi subsp. zooepidemicus MGCS10565 6760372 YP_002123414.1 CDS Sez_1049 NC_011134.1 1083793 1084140 D similar to ref|NP_269275.1| hypothetical protein SPy_1121 [Streptococcus pyogenes M1 GAS]; hypothetical protein 1083793..1084140 Streptococcus equi subsp. zooepidemicus MGCS10565 6760370 YP_002123415.1 CDS rex NC_011134.1 1084386 1085075 D modulates transcription in response to the NADH/NAD(+) redox state; redox-sensing transcriptional repressor Rex 1084386..1085075 Streptococcus equi subsp. zooepidemicus MGCS10565 6761031 YP_002123416.1 CDS Sez_1051 NC_011134.1 1085075 1085782 D similar to ref|NP_607204.1| hypothetical protein spyM18_1080 [Streptococcus pyogenes MGAS8232]; glutamine amidotransferase 1085075..1085782 Streptococcus equi subsp. zooepidemicus MGCS10565 6760368 YP_002123417.1 CDS radC NC_011134.1 1085784 1086461 R Involved in DNA double-strand break repair and recombination. Promotes the annealing of complementary single-stranded DNA and by simulation of RAD51 recombinase; DNA repair protein RadC complement(1085784..1086461) Streptococcus equi subsp. zooepidemicus MGCS10565 6761201 YP_002123418.1 CDS Sez_1053 NC_011134.1 1086627 1087754 R similar to ref|YP_282202.1| hypothetical membrane spanning protein [Streptococcus pyogenes MGAS5005]; permease complement(1086627..1087754) Streptococcus equi subsp. zooepidemicus MGCS10565 6761145 YP_002123419.1 CDS Sez_1054 NC_011134.1 1088119 1088787 R similar to ref|YP_060154.1| Lipase/Acylhydrolase family protein [Streptococcus pyogenes MGAS10394]; lipase/acylhydrolase family protein complement(1088119..1088787) Streptococcus equi subsp. zooepidemicus MGCS10565 6761093 YP_002123420.1 CDS Sez_1055 NC_011134.1 1088938 1090500 R similar to ref|YP_596686.1| chloride channel protein [Streptococcus pyogenes MGAS9429]; Probably acts as an electrical shunt for an outwardly-directed proton pump that is linked to amino acid decarboxylation, as part of the extreme acid resistance (XAR) response.; voltage-gated chloride channel family protein complement(1088938..1090500) Streptococcus equi subsp. zooepidemicus MGCS10565 6761263 YP_002123421.1 CDS potD NC_011134.1 1090629 1091702 R similar to ref|YP_001128516.1| spermidine/putrescine extracellular binding protein [Streptococcus pyogenes str. Manfredo]; Required for the activity of the bacterial periplasmic transport system of putrescine and spermidine. Polyamine binding protein.; spermidine putrescineABC transporter substrate-binding protein PotD complement(1090629..1091702) Streptococcus equi subsp. zooepidemicus MGCS10565 6761212 YP_002123422.1 CDS potC NC_011134.1 1091695 1092471 R similar to ref|NP_607191.1| spermidine/putrescine ABC transporter (permease) [Streptococcus pyogenes MGAS8232]; Required for the activity of the bacterial periplasmic transport system of putrescine and spermidine.; spermidine/putrescine transport system permease PotC complement(1091695..1092471) Streptococcus equi subsp. zooepidemicus MGCS10565 6761105 YP_002123423.1 CDS potB NC_011134.1 1092468 1093262 R similar to ref|YP_280272.1| spermidine/putrescine transport system permease [Streptococcus pyogenes MGAS6180]; Required for the activity of the bacterial periplasmic transport system of putrescine and spermidine.; spermidine/putrescine transport system permease PotB complement(1092468..1093262) Streptococcus equi subsp. zooepidemicus MGCS10565 6761255 YP_002123424.1 CDS potA NC_011134.1 1093246 1094400 R similar to ref|YP_060142.1| PotA [Streptococcus pyogenes MGAS10394]; Part of the ABC transporter complex potABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.; spermidine/putrescine import ATP-binding protein PotA complement(1093246..1094400) Streptococcus equi subsp. zooepidemicus MGCS10565 6761129 YP_002123425.1 CDS murB NC_011134.1 1094446 1095339 R catalyzes the reduction of UDP-N-acetylglucosamine enolpyruvate to form UDP-N-acetylmuramate in peptidoglycan biosynthesis; UDP-N-acetylenolpyruvoylglucosamine reductase complement(1094446..1095339) Streptococcus equi subsp. zooepidemicus MGCS10565 6760989 YP_002123426.1 CDS folK NC_011134.1 1095428 1095934 R similar to ref|YP_598549.1| 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase [Streptococcus pyogenes MGAS10270]; Dihydrofolate biosynthesis; first step, Catalysis of the reaction: ATP + 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine = AMP + 2-amino-7, 8-dihydro-4-hydroxy-6-(diphosphooxymethyl)pteridine.; 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase complement(1095428..1095934) Streptococcus equi subsp. zooepidemicus MGCS10565 6761053 YP_002123427.1 CDS folB NC_011134.1 1095931 1096293 R similar to emb|CAD31136.1| dihydroneopterin aldolase [Streptococcus pyogenes]; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin.; dihydroneopterin aldolase FolB complement(1095931..1096293) Streptococcus equi subsp. zooepidemicus MGCS10565 6761055 YP_002123428.1 CDS folP NC_011134.1 1096297 1097097 R similar to emb|CAA04242.1| dihydropteroate synthase [Streptococcus pyogenes]; DHPS catalyzes the formation of the immediate precursor of folic acid. It is implicated in resistance to sulfonamide.; dihydropteroate synthase FolP complement(1096297..1097097) Streptococcus equi subsp. zooepidemicus MGCS10565 6761140 YP_002123429.1 CDS folE NC_011134.1 1097105 1097671 R similar to emb|CAC39312.1| GTP Cyclohydrolase [Streptococcus pyogenes]; Tetrahydrofolate biosynthesis; first step.; GTP cyclohydrolase I complement(1097105..1097671) Streptococcus equi subsp. zooepidemicus MGCS10565 6761220 YP_002123430.1 CDS folC NC_011134.1 1097729 1098760 R similar to ref|YP_598545.1| Folylpolyglutamate synthase / Dihydrofolate synthase [Streptococcus pyogenes MGAS10270]; Conversion of folates to polyglutamate derivatives.; dihydrofolate synthase / folylpolyglutamate synthase FolC complement(1097729..1098760) Streptococcus equi subsp. zooepidemicus MGCS10565 6761025 YP_002123431.1 CDS thrB NC_011134.1 1099152 1099958 R similar to ref|YP_819981.1| homoserine kinase [Streptococcus thermophilus LMD-9]; Threonine biosynthesis from asparate; fourth step.; homoserine kinase ThrB complement(1099152..1099958) Streptococcus equi subsp. zooepidemicus MGCS10565 6761290 YP_002123432.1 CDS hom NC_011134.1 1100014 1101297 R catalyzes the formation of L-aspartate 4-semialdehyde from L-homoserine; homoserine dehydrogenase complement(1100014..1101297) Streptococcus equi subsp. zooepidemicus MGCS10565 6760365 YP_002123433.1 CDS Sez_1068 NC_011134.1 1101514 1102434 D similar to ref|NP_664560.1| hypothetical protein SpyM3_0756 [Streptococcus pyogenes MGAS315]; Required for the synthesis of linear beta-1,6-linked glucosaminoglycans.; polysaccharide deacetylase 1101514..1102434 Streptococcus equi subsp. zooepidemicus MGCS10565 6760362 YP_002123434.1 CDS sdzB NC_011134.1 1102724 1103530 R similar to ref|YP_061057.1| Streptodornase [Streptococcus pyogenes MGAS10394]; Contributes to resistance to the host immune response in part by degrading neutrophil extracellular traps (NETs).; streptodornase type B SdzB complement(1102724..1103530) Streptococcus equi subsp. zooepidemicus MGCS10565 6760359 YP_002123435.1 CDS ndk NC_011134.1 1104031 1104450 R catalyzes the formation of nucleoside triphosphate from ATP and nucleoside diphosphate; nucleoside diphosphate kinase complement(1104031..1104450) Streptococcus equi subsp. zooepidemicus MGCS10565 6760356 YP_002123436.1 CDS Sez_1071 NC_011134.1 1104453 1104590 D hypothetical protein 1104453..1104590 Streptococcus equi subsp. zooepidemicus MGCS10565 6760354 YP_002123437.1 CDS clpL NC_011134.1 1104821 1106914 D similar to ref|YP_598361.1| ATP-dependent endopeptidase clp ATP-binding subunit clpL [Streptococcus pyogenes MGAS10270]; Could be the ATP-dependent specificity component of an ATP-dependent protease.; ATP-dependent protease ATP-binding subunit ClpL 1104821..1106914 Streptococcus equi subsp. zooepidemicus MGCS10565 6760715 YP_002123438.1 CDS Sez_1073 NC_011134.1 1107098 1110109 R similar to ref|NP_687455.1| cell wall surface anchor family protein [Streptococcus agalactiae 2603V/R]; Unknown, possible adhesin, cognate in GBS has been shown to be immunoprotective in mice.; cell surface protein, RBC-binding protein complement(1107098..1110109) Streptococcus equi subsp. zooepidemicus MGCS10565 6760805 YP_002123439.1 CDS engB NC_011134.1 1110471 1111073 R binds guanine nucleotides; in Escherichia coli depletion results in defective cell division and filamentation; in Bacillus subtilis this gene is essential; ribosome biogenesis GTP-binding protein YsxC complement(1110471..1111073) Streptococcus equi subsp. zooepidemicus MGCS10565 6760718 YP_002123440.1 CDS clpX NC_011134.1 1111080 1112309 R binds and unfolds substrates as part of the ClpXP protease; ATP-dependent protease ATP-binding subunit ClpX complement(1111080..1112309) Streptococcus equi subsp. zooepidemicus MGCS10565 6760780 YP_002123441.1 CDS Sez_1076 NC_011134.1 1112345 1112515 R similar to ref|NP_607088.1| hypothetical protein spyM18_0945 [Streptococcus pyogenes MGAS8232]; hypothetical protein complement(1112345..1112515) Streptococcus equi subsp. zooepidemicus MGCS10565 6760712 YP_002123442.1 CDS dhfR NC_011134.1 1112535 1113035 R similar to ref|YP_602275.1| Dihydrofolate reductase [Streptococcus pyogenes MGAS10750]; Essential step for de novo glycine and purine synthesis, DNA precursor synthesis, and for the conversion of dUMP to dTMP.; dihydrofolate reductase DhfR complement(1112535..1113035) Streptococcus equi subsp. zooepidemicus MGCS10565 6762344 YP_002123443.1 CDS thyA NC_011134.1 1113113 1113952 R ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived; thymidylate synthase complement(1113113..1113952) Streptococcus equi subsp. zooepidemicus MGCS10565 6760778 YP_002123444.1 CDS Sez_1079 NC_011134.1 1114137 1115312 D similar to ref|NP_269080.1| 3-hydroxy-3-methylglutaryl-coenzyme A synthase (HMG-CoA synthase) [Streptococcus pyogenes M1 GAS]; Catalysis of the reaction: acetyl-CoA + H2O + acetoacetyl-CoA = (S)-3-hydroxy-3-methylglutaryl-CoA + CoA.; hydroxymethylglutaryl-CoA synthase 1114137..1115312 Streptococcus equi subsp. zooepidemicus MGCS10565 6760957 YP_002123445.1 CDS hmgA NC_011134.1 1115296 1116582 D similar to ref|NP_607084.1| HMG-CoA reductase [Streptococcus pyogenes MGAS8232]; Converts HMG-CoA to mevalonate.; 3-hydroxy-3-methylglutaryl-CoA reductase 1115296..1116582 Streptococcus equi subsp. zooepidemicus MGCS10565 6762349 YP_002123446.1 CDS Sez_1081 NC_011134.1 1116866 1117858 R catalyzes the isomerization of isopentenyl pyrophosphate to dimethylallyl diphosphate; isopentenyl pyrophosphate isomerase complement(1116866..1117858) Streptococcus equi subsp. zooepidemicus MGCS10565 6762326 YP_002123447.1 CDS Sez_1082 NC_011134.1 1117861 1118757 R similar to ref|YP_598351.1| Phosphomevalonate kinase [Streptococcus pyogenes MGAS10270]; Catalysis of the reaction: ATP + (R)-5-phosphomevalonate = ADP + (R)-5-diphosphomevalonate.; phosphomevalonate kinase complement(1117861..1118757) Streptococcus equi subsp. zooepidemicus MGCS10565 6762320 YP_002123448.1 CDS Sez_1083 NC_011134.1 1118851 1119795 R similar to ref|YP_001128674.1| mevalonate diphosphate decarboxylase [Streptococcus pyogenes str. Manfredo]; Catalysis of the reaction: ATP + (R)-5-diphosphomevalonate = ADP + phosphate + isopentenyl diphosphate + CO2.; diphosphomevalonate decarboxylase complement(1118851..1119795) Streptococcus equi subsp. zooepidemicus MGCS10565 6762341 YP_002123449.1 CDS mvk NC_011134.1 1119777 1120655 R similar to ref|NP_664399.1| mevalonate kinase [Streptococcus pyogenes MGAS315]; Catalysis of the reaction: ATP + (R)-mevalonate = ADP + (R)-5-phosphomevalonate.; mevalonate kinase Mvk complement(1119777..1120655) Streptococcus equi subsp. zooepidemicus MGCS10565 6762317 YP_002123450.1 CDS Sez_1085 NC_011134.1 1121186 1122898 R similar to ref|YP_001198771.1| ABC transporter [Streptococcus suis 05ZYH33]; ABC transporter ATP-binding protein/permease complement(1121186..1122898) Streptococcus equi subsp. zooepidemicus MGCS10565 6762314 YP_002123451.1 CDS Sez_1086 NC_011134.1 1122939 1123961 R similar to ref|YP_001200977.1| ABC-type multidrug transport system, ATPase and permease component [Streptococcus suis 98HAH33]; multidrug resistance transport system ATP-binding protein complement(1122939..1123961) Streptococcus equi subsp. zooepidemicus MGCS10565 6762307 YP_002123452.1 CDS Sez_1087 NC_011134.1 1123916 1124671 R similar to ref|YP_001200977.1| ABC-type multidrug transport system, ATPase and permease component [Streptococcus suis 98HAH33]; multidrug ABC transporter ATPase/permease complement(1123916..1124671) Streptococcus equi subsp. zooepidemicus MGCS10565 6762315 YP_002123453.1 CDS Sez_1088 NC_011134.1 1125109 1127115 D similar to ref|YP_060013.1| 5'-nucleotidase [Streptococcus pyogenes MGAS10394]; cell surface 5'-nucleotidase 1125109..1127115 Streptococcus equi subsp. zooepidemicus MGCS10565 6762313 YP_002123454.1 CDS def NC_011134.1 1127308 1127718 R cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+); peptide deformylase complement(1127308..1127718) Streptococcus equi subsp. zooepidemicus MGCS10565 6762293 YP_002123455.1 CDS gdh NC_011134.1 1127850 1129199 R converts 2-oxoglutarate to glutamate; in Escherichia coli this enzyme plays a role in glutamate synthesis when the cell is under energy restriction; uses NADPH; forms a homohexamer; glutamate dehydrogenase complement(1127850..1129199) Streptococcus equi subsp. zooepidemicus MGCS10565 6762305 YP_002123456.1 CDS Sez_1091 NC_011134.1 1129340 1131112 R similar to ref|YP_001450473.1| permease ATP-binding protein [Streptococcus gordonii str. Challis substr. CH1]; ABC transporter ATP-binding protein/permease complement(1129340..1131112) Streptococcus equi subsp. zooepidemicus MGCS10565 6762300 YP_002123457.1 CDS Sez_1092 NC_011134.1 1131112 1132857 R similar to ref|YP_001200357.1| ABC transporter, ATP-binding protein [Streptococcus suis 98HAH33]; ABC transporter ATP-binding protein/permease complement(1131112..1132857) Streptococcus equi subsp. zooepidemicus MGCS10565 6762298 YP_002123458.1 CDS Sez_1093 NC_011134.1 1132962 1134830 R similar to ref|YP_598341.1| ABC transporter ATP-binding protein uup [Streptococcus pyogenes MGAS10270]; ABC transporter ATPase complement(1132962..1134830) Streptococcus equi subsp. zooepidemicus MGCS10565 6762287 YP_002123459.1 CDS cca NC_011134.1 1134823 1136019 R catalyzes the addition and repair of the 3'-terminal CCA sequence in tRNA; these proteins belong to the CCA-adding enzyme subfamily 2 which does not have phosphohydrolase activity; tRNA CCA-pyrophosphorylase complement(1134823..1136019) Streptococcus equi subsp. zooepidemicus MGCS10565 6762291 YP_002123460.1 CDS Sez_1095 NC_011134.1 1136138 1136986 R similar to ref|ZP_00366624.1| COG1307: Uncharacterized protein conserved in bacteria [Streptococcus pyogenes M49 591]; DegV family protein complement(1136138..1136986) Streptococcus equi subsp. zooepidemicus MGCS10565 6762274 YP_002123461.1 CDS Sez_1096 NC_011134.1 1136986 1137399 R similar to ref|YP_060007.1| Transposase [Streptococcus pyogenes MGAS10394]; transposase complement(1136986..1137399) Streptococcus equi subsp. zooepidemicus MGCS10565 6762280 YP_002123462.1 CDS Sez_1097 NC_011134.1 1137589 1138299 R similar to ref|ZP_00366628.1| COG1705: Muramidase (flagellum-specific) [Streptococcus pyogenes M49 591]; Hydrolyzes the cell wall of E.faecalis and M.lysodeikticus. May play an important role in cell wall growth and cell separation.; autolysin precursor complement(1137589..1138299) Streptococcus equi subsp. zooepidemicus MGCS10565 6762276 YP_002123463.1 CDS citT NC_011134.1 1138746 1140104 R similar to ref|ZP_02146542.1| Di- and tricarboxylate transporter [Phaeobacter gallaeciensis BS107]; Responsible For The Uptake Of Citrate In Exchange To The Efflux Of Succinate. Has A Relatively Broad Specificity For C(4)- Dicarboxylates And Tricarboxylates.; di- and tricarboxylate transporters complement(1138746..1140104) Streptococcus equi subsp. zooepidemicus MGCS10565 6762272 YP_002123464.1 CDS Sez_1099 NC_011134.1 1140513 1140719 R similar to ref|ZP_02093443.1| hypothetical protein PEPMIC_00194 [Peptostreptococcus micros ATCC 33270]; hypothetical protein complement(1140513..1140719) Streptococcus equi subsp. zooepidemicus MGCS10565 6762270 YP_002123465.1 CDS Sez_1100 NC_011134.1 1141191 1141424 R similar to ref|ZP_02094098.1| hypothetical protein PEPMIC_00856 [Peptostreptococcus micros ATCC 33270]; hypothetical protein complement(1141191..1141424) Streptococcus equi subsp. zooepidemicus MGCS10565 6762264 YP_002123466.1 CDS Sez_1101 NC_011134.1 1141573 1141782 R similar to ref|ZP_02091657.1| hypothetical protein FAEPRAM212_01939 [Faecalibacterium prausnitzii M21/2]; hypothetical protein complement(1141573..1141782) Streptococcus equi subsp. zooepidemicus MGCS10565 6762261 YP_002123467.1 CDS Sez_1102 NC_011134.1 1142342 1142941 R similar to ref|YP_596450.1| N-acetylmuramidase [Streptococcus pyogenes MGAS9429]; Cognates hydrolyze the cell wall of L.lactis and M.lysodeikticus. Required for cell separation during growth.; N-acetylmuramidase precursor complement(1142342..1142941) Streptococcus equi subsp. zooepidemicus MGCS10565 6762259 YP_002123468.1 CDS Sez_1103 NC_011134.1 1143045 1143173 R similar to gb|EDQ65758.1| predicted protein [Physcomitrella patens subsp. patens]; hypothetical protein complement(1143045..1143173) Streptococcus equi subsp. zooepidemicus MGCS10565 6762256 YP_002123469.1 CDS fruA NC_011134.1 1143529 1145475 R similar to ref|NP_269062.1| fructose-specific enzyme II, PTS system BC component [Streptococcus pyogenes M1 GAS]; The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. This system is involved in fructose transport.; PTS system fructose-specific transporter subunit IIABC complement(1143529..1145475) Streptococcus equi subsp. zooepidemicus MGCS10565 6762253 YP_002123470.1 CDS fruK NC_011134.1 1145472 1146383 R similar to ref|YP_596448.1| 1-phosphofructokinase [Streptococcus pyogenes MGAS9429]; Catalysis of the reaction: ATP + D-tagatose 6-phosphate = ADP + D-tagatose 1,6-bisphosphate.; tagatose-6-phosphate kinase / 1-phosphofructokinase FruK complement(1145472..1146383) Streptococcus equi subsp. zooepidemicus MGCS10565 6762247 YP_002123471.1 CDS glpR NC_011134.1 1146380 1147093 R similar to ref|NP_269060.1| transcriptional repressor [Streptococcus pyogenes M1 GAS]; Repressor of the glycerol-3-phosphate regulon.; glycerol-3-phosphate regulon repressor GlpR complement(1146380..1147093) Streptococcus equi subsp. zooepidemicus MGCS10565 6762244 YP_002123472.1 CDS Sez_1107 NC_011134.1 1147528 1148451 R ketopantoate reductase; catalyzes the NADPH reduction of ketopantoate to pantoate; functions in pantothenate (vitamin B5) biosynthesis; 2-dehydropantoate 2-reductase complement(1147528..1148451) Streptococcus equi subsp. zooepidemicus MGCS10565 6762223 YP_002123473.1 CDS Sez_1108 NC_011134.1 1148463 1149521 R similar to ref|NP_269058.1| regulatory protein [Streptococcus pyogenes M1 GAS]; regulatory protein complement(1148463..1149521) Streptococcus equi subsp. zooepidemicus MGCS10565 6762239 YP_002123474.1 CDS Sez_1109 NC_011134.1 1149653 1150645 R similar to ref|ZP_00365412.1| COG0492: Thioredoxin reductase [Streptococcus pyogenes M49 591]; Catalysis of the reaction: thioredoxin + NADP+ = thioredoxin disulfide + NADPH + H+.; thioredoxin reductase complement(1149653..1150645) Streptococcus equi subsp. zooepidemicus MGCS10565 6762214 YP_002123475.1 CDS trmD NC_011134.1 1150645 1151376 R methylates guanosine-37 in various tRNAs; uses S-adenosyl-L-methionine to transfer methyl group to tRNA; tRNA (guanine-N(1)-)-methyltransferase complement(1150645..1151376) Streptococcus equi subsp. zooepidemicus MGCS10565 6762210 YP_002123476.1 CDS rimM NC_011134.1 1151366 1151884 R Essential for efficient processing of 16S rRNA; 16S rRNA-processing protein RimM complement(1151366..1151884) Streptococcus equi subsp. zooepidemicus MGCS10565 6762231 YP_002123477.1 CDS Sez_1112 NC_011134.1 1152264 1153067 R similar to ref|YP_596865.1| transposase [Streptococcus pyogenes MGAS9429]; transposase IS861 orfB complement(1152264..1153067) Streptococcus equi subsp. zooepidemicus MGCS10565 6762176 YP_002123478.1 CDS Sez_1113 NC_011134.1 1153091 1153606 R similar to ref|YP_602677.1| Transposase [Streptococcus pyogenes MGAS10750]; transposase IS861 orfA complement(1153091..1153606) Streptococcus equi subsp. zooepidemicus MGCS10565 6762220 YP_002123479.1 CDS Sez_1114 NC_011134.1 1154088 1157573 R similar to ref|ZP_00785378.1| subtilase [Streptococcus agalactiae COH1]; Unknown, has an 115aa domain with similarity to internalin A of Listeria monocytogenes.; hypothetical protein complement(1154088..1157573) Streptococcus equi subsp. zooepidemicus MGCS10565 6762217 YP_002123480.1 CDS Sez_1115 NC_011134.1 1157827 1158780 R similar to ref|ZP_00874436.1| Integrase, catalytic region [Streptococcus suis 89/1591]; transposase IS1239 complement(1157827..1158780) Streptococcus equi subsp. zooepidemicus MGCS10565 6762190 YP_002123481.1 CDS Sez_1116 NC_011134.1 1158849 1159505 R similar to ref|ZP_02093841.1| hypothetical protein PEPMIC_00596 [Peptostreptococcus micros ATCC 33270]; resolvase/integrase complement(1158849..1159505) Streptococcus equi subsp. zooepidemicus MGCS10565 6762205 YP_002123482.1 CDS Sez_1117 NC_011134.1 1159672 1159911 R similar to ref|ZP_00366185.1| COG1837: Predicted RNA-binding protein (contains KH domain) [Streptococcus pyogenes M49 591]; hypothetical protein complement(1159672..1159911) Streptococcus equi subsp. zooepidemicus MGCS10565 6762207 YP_002123483.1 CDS rpsP NC_011134.1 1159921 1160166 R similar to ref|NP_269049.1| 30S ribosomal protein S16 [Streptococcus pyogenes M1 GAS]; In addition to being a ribosomal protein, S16 also has a cation-dependent endonuclease activity.; 30S ribosomal protein S16 complement(1159921..1160166) Streptococcus equi subsp. zooepidemicus MGCS10565 6762202 YP_002123484.1 CDS Sez_1119 NC_011134.1 1160636 1161172 R similar to ref|NP_735374.1| hypothetical protein gbs0925 [Streptococcus agalactiae NEM316]; hypothetical protein complement(1160636..1161172) Streptococcus equi subsp. zooepidemicus MGCS10565 6762175 YP_002123485.1 CDS Sez_1120 NC_011134.1 1161246 1162469 R similar to ref|YP_282009.1| ABC transporter permease [Streptococcus pyogenes MGAS5005]; ABC transporter permease complement(1161246..1162469) Streptococcus equi subsp. zooepidemicus MGCS10565 6762173 YP_002123486.1 CDS Sez_1121 NC_011134.1 1162481 1163191 R similar to ref|YP_280095.1| ABC transporter ATP-binding protein [Streptococcus pyogenes MGAS6180]; ABC transporter ATP-binding protein complement(1162481..1163191) Streptococcus equi subsp. zooepidemicus MGCS10565 6762185 YP_002123487.1 CDS Sez_1122 NC_011134.1 1163191 1164453 R similar to emb|CAM30488.1| exported protein [Streptococcus pyogenes str. Manfredo]; hypothetical protein complement(1163191..1164453) Streptococcus equi subsp. zooepidemicus MGCS10565 6762177 YP_002123488.1 CDS carB NC_011134.1 1164709 1167912 R four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate; CarB is responsible for the amidotransferase activity; carbamoyl phosphate synthase large subunit complement(1164709..1167912) Streptococcus equi subsp. zooepidemicus MGCS10565 6762154 YP_002123489.1 CDS carA NC_011134.1 1168304 1169440 R catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers; carbamoyl phosphate synthase small subunit complement(1168304..1169440) Streptococcus equi subsp. zooepidemicus MGCS10565 6762155 YP_002123490.1 CDS pyrB NC_011134.1 1169418 1170353 R catalyzes the transfer of the carbamoyl moiety from carbamoyl phosphate to L- aspartate in pyrimidine biosynthesis; aspartate carbamoyltransferase complement(1169418..1170353) Streptococcus equi subsp. zooepidemicus MGCS10565 6762147 YP_002123491.1 CDS pyrP NC_011134.1 1170411 1171670 R similar to ref|YP_001128709.1| uracil permease [Streptococcus pyogenes str. Manfredo]; Transport of uracil in the cell.; uracil permease PyrP complement(1170411..1171670) Streptococcus equi subsp. zooepidemicus MGCS10565 6762146 YP_002123492.1 CDS pyrR NC_011134.1 1171686 1172207 R regulates pyrimidine biosynthesis by binding to the mRNA of the pyr genes, also has been shown to have uracil phosphoribosyltransferase activity; bifunctional pyrimidine regulatory protein PyrR/uracil phosphoribosyltransferase complement(1171686..1172207) Streptococcus equi subsp. zooepidemicus MGCS10565 6762142 YP_002123493.1 CDS Sez_1128 NC_011134.1 1172566 1173183 D similar to ref|NP_815585.1| hypothetical protein EF1903 [Enterococcus faecalis V583]; membrane-associated alkaline phosphatase 1172566..1173183 Streptococcus equi subsp. zooepidemicus MGCS10565 6762134 YP_002123494.1 CDS Sez_1129 NC_011134.1 1173264 1174154 R similar to ref|YP_059974.1| Ribosomal large subunit pseudouridine synthase D [Streptococcus pyogenes MGAS10394]; Responsible For Synthesis Of Pseudouridine From Uracil At Positions 1911, 1915 And 1917 In 23s Ribosomal RNA.; ribosomal large subunit pseudouridine synthase D complement(1173264..1174154) Streptococcus equi subsp. zooepidemicus MGCS10565 6762131 YP_002123495.1 CDS lspA NC_011134.1 1174144 1174581 R lipoprotein signal peptidase; integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis; lipoprotein signal peptidase complement(1174144..1174581) Streptococcus equi subsp. zooepidemicus MGCS10565 6762129 YP_002123496.1 CDS Sez_1131 NC_011134.1 1174623 1174757 R hypothetical protein complement(1174623..1174757) Streptococcus equi subsp. zooepidemicus MGCS10565 6762128 YP_002123497.1 CDS Sez_1132 NC_011134.1 1174831 1175760 R similar to ref|YP_280085.1| transcriptional regulator, LysR family [Streptococcus pyogenes MGAS6180]; cysteine and methionine metabolism regulator complement(1174831..1175760) Streptococcus equi subsp. zooepidemicus MGCS10565 6762127 YP_002123498.1 CDS rpmA NC_011134.1 1176167 1176436 R involved in the peptidyltransferase reaction during translation; 50S ribosomal protein L27 complement(1176167..1176436) Streptococcus equi subsp. zooepidemicus MGCS10565 6762097 YP_002123499.1 CDS Sez_1134 NC_011134.1 1176482 1176814 R similar to ref|YP_001450118.1| ribosomal protein [Streptococcus gordonii str. Challis substr. CH1]; hypothetical protein complement(1176482..1176814) Streptococcus equi subsp. zooepidemicus MGCS10565 6762117 YP_002123500.1 CDS rplU NC_011134.1 1176827 1177141 R similar to ref|NP_269034.1| 50S ribosomal protein L21 [Streptococcus pyogenes M1 GAS]; This protein binds to 23S ribosomal RNA in the presence of protein L20.; 50S ribosomal protein L21 complement(1176827..1177141) Streptococcus equi subsp. zooepidemicus MGCS10565 6762089 YP_002123501.1 CDS capA NC_011134.1 1177371 1178564 R similar to ref|YP_280081.1| capsule biosynthesis protein [Streptococcus pyogenes MGAS6180]; capsule biosynthesis protein CapA-like complement(1177371..1178564) Streptococcus equi subsp. zooepidemicus MGCS10565 6762108 YP_002123502.1 CDS Sez_1137 NC_011134.1 1178796 1179446 D similar to ref|NP_607417.1| hypothetical protein spyM18_1310 [Streptococcus pyogenes MGAS8232]; lipoprotein 1178796..1179446 Streptococcus equi subsp. zooepidemicus MGCS10565 6762075 YP_002123503.1 CDS Sez_1138 NC_011134.1 1179744 1180964 R similar to ref|YP_001449814.1| permease [Streptococcus gordonii str. Challis substr. CH1] gb|AAG32545.1| Dsg [Streptococcus gordonii]; macrolide-efflux protein complement(1179744..1180964) Streptococcus equi subsp. zooepidemicus MGCS10565 6762072 YP_002123504.1 CDS Sez_1139 NC_011134.1 1181036 1181209 R hypothetical protein complement(1181036..1181209) Streptococcus equi subsp. zooepidemicus MGCS10565 6762087 YP_002123505.1 CDS Sez_1140 NC_011134.1 1181509 1182285 R similar to ref|ZP_01821646.1| transcriptional activator, Rgg/GadR/MutR family protein, C-terminal domain [Streptococcus pneumoniae SP6-BS73]; positive transcriptional regulator MutR family complement(1181509..1182285) Streptococcus equi subsp. zooepidemicus MGCS10565 6762085 YP_002123506.1 CDS rpsA NC_011134.1 1184565 1185767 R in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins; 30S ribosomal protein S1 complement(1184565..1185767) Streptococcus equi subsp. zooepidemicus MGCS10565 6762056 YP_002123507.1 CDS Sez_1145 NC_011134.1 1186146 1186376 R similar to ref|YP_602302.1| hypothetical cytosolic protein [Streptococcus pyogenes MGAS10750]; hypothetical protein complement(1186146..1186376) Streptococcus equi subsp. zooepidemicus MGCS10565 6761144 YP_002123508.1 CDS ilvE NC_011134.1 1186444 1187466 R catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids; branched-chain amino acid aminotransferase complement(1186444..1187466) Streptococcus equi subsp. zooepidemicus MGCS10565 6762064 YP_002123509.1 CDS parC NC_011134.1 1187567 1190026 R decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling; DNA topoisomerase IV subunit A complement(1187567..1190026) Streptococcus equi subsp. zooepidemicus MGCS10565 6762060 YP_002123510.1 CDS Sez_1148 NC_011134.1 1190500 1191363 R similar to ref|YP_001128646.1| hypothetical protein SpyM51096 [Streptococcus pyogenes str. Manfredo]; hypothetical protein complement(1190500..1191363) Streptococcus equi subsp. zooepidemicus MGCS10565 6762055 YP_002123511.1 CDS parE NC_011134.1 1191417 1193366 R decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling; DNA topoisomerase IV subunit B complement(1191417..1193366) Streptococcus equi subsp. zooepidemicus MGCS10565 6762022 YP_002123512.1 CDS Sez_1150 NC_011134.1 1193499 1194146 D involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsX; glycerol-3-phosphate acyltransferase PlsY 1193499..1194146 Streptococcus equi subsp. zooepidemicus MGCS10565 6762049 YP_002123513.1 CDS pyrC NC_011134.1 1194200 1195612 R catalyzes the formation of N-carbamoyl-L-aspartate from (S)-dihydroorotate in pyrimidine biosynthesis; dihydroorotase complement(1194200..1195612) Streptococcus equi subsp. zooepidemicus MGCS10565 6762028 YP_002123514.1 CDS ung NC_011134.1 1195707 1196360 R Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine; uracil-DNA glycosylase complement(1195707..1196360) Streptococcus equi subsp. zooepidemicus MGCS10565 6761979 YP_002123515.1 CDS Sez_1153 NC_011134.1 1196372 1196746 R similar to gb|EDK88467.1| possible acetyltransferase [Fusobacterium nucleatum subsp.; acetyltransferase complement(1196372..1196746) Streptococcus equi subsp. zooepidemicus MGCS10565 6762042 YP_002123516.1 CDS Sez_1154 NC_011134.1 1196910 1197563 R similar to ref|NP_664424.1| ABC transporter (permease) [Streptococcus pyogenes MGAS315]; Part of a binding-protein-dependent transport system. Probably responsible for the translocation of the substrate across the membrane.; amino-acid ABC transporter permease complement(1196910..1197563) Streptococcus equi subsp. zooepidemicus MGCS10565 6762033 YP_002123517.1 CDS Sez_1155 NC_011134.1 1197591 1198475 R similar to ref|NP_269099.1| ABC transporter (binding protein) [Streptococcus pyogenes M1 GAS]; Probably part of a binding-protein-dependent transport system.; cystine ABC transporter substrate-binding lipoprotein precursor complement(1197591..1198475) Streptococcus equi subsp. zooepidemicus MGCS10565 6762026 YP_002123518.1 CDS Sez_1156 NC_011134.1 1198577 1200031 R catalyzes the hydrolysis of a monocarboxylic acid amid to form a monocarboxylate and ammonia; amidase complement(1198577..1200031) Streptococcus equi subsp. zooepidemicus MGCS10565 6762015 YP_002123519.1 CDS Sez_1157 NC_011134.1 1200263 1200982 R similar to ref|ZP_00789806.1| acetyltransferase, GNAT family [Streptococcus agalactiae 515]; GNAT family acetyltransferase complement(1200263..1200982) Streptococcus equi subsp. zooepidemicus MGCS10565 6762010 YP_002123520.1 CDS pyrE NC_011134.1 1201057 1201692 R similar to ref|NP_721600.1| orotate phosphoribosyltransferase [Streptococcus mutans UA159]; Catalysis of the reaction: orotidine 5'-phosphate + diphosphate = orotate + 5-phospho-alpha-D-ribose 1-diphosphate.; orotate phosphoribosyltransferase PyrE complement(1201057..1201692) Streptococcus equi subsp. zooepidemicus MGCS10565 6761974 YP_002123521.1 CDS pyrF NC_011134.1 1201752 1202444 R type 1 subfamily; involved in last step of pyrimidine biosynthesis; converts orotidine 5'-phosphate to UMP and carbon dioxide; OMP decarboxylase; OMPDCase; OMPdecase; orotidine 5'-phosphate decarboxylase complement(1201752..1202444) Streptococcus equi subsp. zooepidemicus MGCS10565 6762001 YP_002123522.1 CDS Sez_1160 NC_011134.1 1203061 1203510 R similar to ref|YP_001128656.1| hypothetical protein SpyM51106 [Streptococcus pyogenes str. Manfredo]; hypothetical protein complement(1203061..1203510) Streptococcus equi subsp. zooepidemicus MGCS10565 6761999 YP_002123523.1 CDS Sez_1161 NC_011134.1 1203849 1204757 D similar to ref|YP_596489.1| transcriptional regulators, LysR family [Streptococcus pyogenes MGAS9429]; HTH-type transcriptional regulator 1203849..1204757 Streptococcus equi subsp. zooepidemicus MGCS10565 6761978 YP_002123524.1 CDS Sez_1162 NC_011134.1 1204888 1205706 R similar to ref|YP_060035.1| Histidine protein kinase [Streptococcus pyogenes MGAS10394]; histidine protein kinase complement(1204888..1205706) Streptococcus equi subsp. zooepidemicus MGCS10565 6761993 YP_002123525.1 CDS punA NC_011134.1 1205764 1206573 R catalyzes the formation of a purine and ribose phosphate from a purine nucleoside; in E. coli this enzyme functions in xanthosine degradation; purine nucleoside phosphorylase complement(1205764..1206573) Streptococcus equi subsp. zooepidemicus MGCS10565 6761985 YP_002123526.1 CDS deoB NC_011134.1 1206787 1207998 R catalyzes the transfer of phosphate between the C1 and C5 carbons of pentose; phosphopentomutase complement(1206787..1207998) Streptococcus equi subsp. zooepidemicus MGCS10565 6761965 YP_002123527.1 CDS rpiA NC_011134.1 1208076 1208759 R Catalyzes D-ribose 5-phosphate --> D-ribulose 5-phosphate in the nonoxidative branch of the pentose phosphate pathway; ribose-5-phosphate isomerase A complement(1208076..1208759) Streptococcus equi subsp. zooepidemicus MGCS10565 6761977 YP_002123528.1 CDS Sez_1166 NC_011134.1 1208834 1208989 R hypothetical protein complement(1208834..1208989) Streptococcus equi subsp. zooepidemicus MGCS10565 6761959 YP_002123529.1 CDS Sez_1167 NC_011134.1 1209193 1209507 R similar to ref|YP_001035335.1| hypothetical protein SSA_1387 [Streptococcus sanguinis SK36]; hypothetical protein complement(1209193..1209507) Streptococcus equi subsp. zooepidemicus MGCS10565 6761972 YP_002123530.1 CDS Sez_1168 NC_011134.1 1209514 1210185 R hypothetical protein complement(1209514..1210185) Streptococcus equi subsp. zooepidemicus MGCS10565 6761968 YP_002123531.1 CDS Sez_1169 NC_011134.1 1210213 1210893 R hypothetical protein complement(1210213..1210893) Streptococcus equi subsp. zooepidemicus MGCS10565 6761964 YP_002123532.1 CDS Sez_1170 NC_011134.1 1210921 1211559 R hypothetical protein complement(1210921..1211559) Streptococcus equi subsp. zooepidemicus MGCS10565 6761961 YP_002123533.1 CDS Sez_1171 NC_011134.1 1211626 1212306 R hypothetical protein complement(1211626..1212306) Streptococcus equi subsp. zooepidemicus MGCS10565 6761951 YP_002123534.1 CDS Sez_1172 NC_011134.1 1212306 1213904 R similar to ref|YP_850136.1| hypothetical protein lwe1939 [Listeria welshimeri serovar 6b str. SLCC5334]; hypothetical protein complement(1212306..1213904) Streptococcus equi subsp. zooepidemicus MGCS10565 6761936 YP_002123535.1 CDS Sez_1173 NC_011134.1 1213906 1214238 R hypothetical protein complement(1213906..1214238) Streptococcus equi subsp. zooepidemicus MGCS10565 6761931 YP_002123536.1 CDS Sez_1174 NC_011134.1 1214243 1214557 R hypothetical protein complement(1214243..1214557) Streptococcus equi subsp. zooepidemicus MGCS10565 6761942 YP_002123537.1 CDS trmE NC_011134.1 1215018 1216394 D in Escherichia coli this protein is involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2-thiouridine, which is found in the wobble position of some tRNAs and affects ribosomal frameshifting; shows potassium-dependent dimerization and GTP hydrolysis; also involved in regulation of glutamate-dependent acid resistance and activation of gadE; tRNA modification GTPase TrmE 1215018..1216394 Streptococcus equi subsp. zooepidemicus MGCS10565 6761939 YP_002123538.1 CDS Sez_1178 NC_011134.1 1218149 1218751 R similar to ref|NP_269235.1| NADH dehydrogenase [Streptococcus pyogenes M1 GAS]; Catalysis of the reaction: 5,6,7,8-tetrahydropteridine + NAD(P)+ = a 6,7-dihydropteridine + NAD(P)H + H.; oxygen-insensitive NAD(P)H nitroreductase / dihydropteridine reductase complement(1218149..1218751) Streptococcus equi subsp. zooepidemicus MGCS10565 6761908 YP_002123539.1 CDS uvrC NC_011134.1 1218879 1220663 R The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision; excinuclease ABC subunit C complement(1218879..1220663) Streptococcus equi subsp. zooepidemicus MGCS10565 6761921 YP_002123540.1 CDS Sez_1180 NC_011134.1 1220916 1221953 R similar to ref|ZP_00784614.1| iron ABC transporter, iron-binding protein [Streptococcus agalactiae COH1]; Required For The Activity Of The Bacterial Periplasmic Transport System Of Putrescine And Spermidine. Polyamine Binding Protein.; ferric iron ABC transporter iron-binding protein complement(1220916..1221953) Streptococcus equi subsp. zooepidemicus MGCS10565 6761896 YP_002123541.1 CDS yesN NC_011134.1 1221950 1222735 R similar to ref|NP_688934.1| DNA-binding response regulator [Streptococcus agalactiae 2603V/R]; Member Of The Two-Component Regulatory System Atos/Atoc Involved In The Transcriptional Regulation Of The Ato Genes For Acetoacetate Metabolism. Also An Inhibitor Of Polyamine Biosynthesis.; TCS response regulator YesN-like complement(1221950..1222735) Streptococcus equi subsp. zooepidemicus MGCS10565 6761894 YP_002123542.1 CDS manZ NC_011134.1 1224545 1225333 R similar to ref|ZP_00780193.1| PTS system, IID component [Streptococcus agalactiae 18RS21]; The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. This system is involved in mannose transport.; mannose permease IID component ManZ complement(1224545..1225333) Streptococcus equi subsp. zooepidemicus MGCS10565 6761900 YP_002123543.1 CDS manY NC_011134.1 1225369 1226178 R similar to ref|YP_060120.1| PTS system, mannose/fructose family IIC component [Streptococcus pyogenes MGAS10394]; The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. This system is involved in mannose transport.; mannose permease IIC component ManY complement(1225369..1226178) Streptococcus equi subsp. zooepidemicus MGCS10565 6761876 YP_002123544.1 CDS Sez_1186 NC_011134.1 1226196 1226687 R similar to ref|ZP_00784628.1| PTS system, IIB component [Streptococcus agalactiae COH1]; PTS system mannose/fructose family transporter subunit IIB complement(1226196..1226687) Streptococcus equi subsp. zooepidemicus MGCS10565 6761895 YP_002123545.1 CDS Sez_1187 NC_011134.1 1226702 1227220 R similar to ref|YP_602425.1| PTS system, mannose/fructose family IIA component [Streptococcus pyogenes MGAS10750]; PTS system mannose/fructose family transporter subunit IIA complement(1226702..1227220) Streptococcus equi subsp. zooepidemicus MGCS10565 6761892 YP_002123546.1 CDS Sez_1188 NC_011134.1 1227471 1228508 R similar to ref|YP_001128544.1| hypothetical protein SpyM50987 [Streptococcus pyogenes str. Manfredo]; hypothetical protein complement(1227471..1228508) Streptococcus equi subsp. zooepidemicus MGCS10565 6761886 YP_002123547.1 CDS msrB NC_011134.1 1228777 1229271 R this stereospecific enzymes reduces the R isomer of methionine sulfoxide while MsrA reduces the S form; provides protection against oxidative stress; methionine sulfoxide reductase B complement(1228777..1229271) Streptococcus equi subsp. zooepidemicus MGCS10565 6761882 YP_002123548.1 CDS Sez_1190 NC_011134.1 1229247 1229384 R hypothetical protein complement(1229247..1229384) Streptococcus equi subsp. zooepidemicus MGCS10565 6761878 YP_002123549.1 CDS lepA NC_011134.1 1229739 1231571 R binds to the ribosome on the universally-conserved alpha-sarcin loop; GTP-binding protein LepA complement(1229739..1231571) Streptococcus equi subsp. zooepidemicus MGCS10565 6761856 YP_002123550.1 CDS Sez_1192 NC_011134.1 1232028 1232204 R hypothetical protein complement(1232028..1232204) Streptococcus equi subsp. zooepidemicus MGCS10565 6761838 YP_002123551.1 CDS Sez_1194 NC_011134.1 1232657 1232998 R similar to ref|YP_803634.1| Gene info Predicted prebacteriocin [Pediococcus pentosaceus ATCC 25745]; Bacteriocin; bacteriocin complement(1232657..1232998) Streptococcus equi subsp. zooepidemicus MGCS10565 6761857 YP_002123552.1 CDS Sez_1195 NC_011134.1 1232980 1233165 R similar to gb|ABD60751.1| class IIa sec-dependent bacteriocin [Enterococcus faecium]; Bacteriocin; bacteriocin complement(1232980..1233165) Streptococcus equi subsp. zooepidemicus MGCS10565 6761840 YP_002123553.1 CDS lcnC NC_011134.1 1233380 1233613 D similar to ref|ZP_01821306.1| Bacteriocin processing peptidase / Bacteriocin export ABC transporter [Streptococcus pneumoniae SP6-BS73]; Involved in the export process of a bacteriocin lactococcin.; lactococcin transport/processing ATP-binding protein LcnC-like 1233380..1233613 Streptococcus equi subsp. zooepidemicus MGCS10565 6761851 YP_002123554.1 CDS Sez_1197 NC_011134.1 1233580 1233867 D similar to ref|ZP_01823865.1| hypothetical protein CGSSp9BS68_01433 [Streptococcus pneumoniae SP9-BS68]; ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain [Defense mechanisms].; bacteriocin processing peptidase 1233580..1233867 Streptococcus equi subsp. zooepidemicus MGCS10565 6761835 YP_002123555.1 CDS blpC NC_011134.1 1235337 1235492 D similar to ref|ZP_01817231.1| peptide pheromone BlpC [Streptococcus pneumoniae SP3-BS71]; BlpC bacteriocin-like peptide 1235337..1235492 Streptococcus equi subsp. zooepidemicus MGCS10565 6761845 YP_002123556.1 CDS Sez_1201 NC_011134.1 1235674 1235964 R similar to ref|YP_001200659.1| transposase of IS200 family [Streptococcus suis 98HAH33]; transposase of IS200 family complement(1235674..1235964) Streptococcus equi subsp. zooepidemicus MGCS10565 6761820 YP_002123557.1 CDS Sez_1202 NC_011134.1 1236426 1236899 R similar to ref|YP_001198456.1| transposase of IS200 family [Streptococcus suis 05ZYH33]; transposase IS200 Family complement(1236426..1236899) Streptococcus equi subsp. zooepidemicus MGCS10565 6761833 YP_002123558.1 CDS Sez_1203 NC_011134.1 1236962 1237099 R hypothetical protein complement(1236962..1237099) Streptococcus equi subsp. zooepidemicus MGCS10565 6762243 YP_002123559.1 CDS rplL NC_011134.1 1237177 1237557 R present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulates GTPase activity of translation factors; 50S ribosomal protein L7/L12 complement(1237177..1237557) Streptococcus equi subsp. zooepidemicus MGCS10565 6762099 YP_002123560.1 CDS rplJ NC_011134.1 1237607 1238107 R binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit; 50S ribosomal protein L10 complement(1237607..1238107) Streptococcus equi subsp. zooepidemicus MGCS10565 6762213 YP_002123561.1 CDS Sez_1206 NC_011134.1 1238397 1239044 R similar to ref|YP_280215.1| hypothetical membrane spanning protein [Streptococcus pyogenes MGAS6180]; hypothetical protein complement(1238397..1239044) Streptococcus equi subsp. zooepidemicus MGCS10565 6762193 YP_002123562.1 CDS Sez_1207 NC_011134.1 1239041 1239808 R similar to ref|YP_602413.1| Haloacid dehalogenase-like hydrolase [Streptococcus pyogenes MGAS10750]; Predicted to act in N-acetylglucosamine utilization subsystem.; hydrolase HAD superfamily complement(1239041..1239808) Streptococcus equi subsp. zooepidemicus MGCS10565 6762174 YP_002123563.1 CDS Sez_1208 NC_011134.1 1239808 1240560 R similar to ref|YP_282129.1| acyl-acyl carrier protein thioesterase [Streptococcus pyogenes MGAS5005]; acyl-ACP thioesterase complement(1239808..1240560) Streptococcus equi subsp. zooepidemicus MGCS10565 6762209 YP_002123564.1 CDS Sez_1209 NC_011134.1 1240571 1241701 R catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III; coproporphyrinogen III oxidase complement(1240571..1241701) Streptococcus equi subsp. zooepidemicus MGCS10565 6762159 YP_002123565.1 CDS Sez_1210 NC_011134.1 1241768 1242454 R similar to ref|ZP_00875329.1| GCN5-related N-acetyltransferase [Streptococcus suis 89/1591]; acetyltransferase GNAT Family complement(1241768..1242454) Streptococcus equi subsp. zooepidemicus MGCS10565 6762237 YP_002123566.1 CDS glmM NC_011134.1 1242488 1243840 R catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; phosphoglucosamine mutase complement(1242488..1243840) Streptococcus equi subsp. zooepidemicus MGCS10565 6762194 YP_002123567.1 CDS Sez_1212 NC_011134.1 1243892 1244848 R similar to ref|NP_664474.1| hypothetical protein SpyM3_0670 [Streptococcus pyogenes MGAS315]; hypothetical protein complement(1243892..1244848) Streptococcus equi subsp. zooepidemicus MGCS10565 6760434 YP_002123568.1 CDS Sez_1213 NC_011134.1 1244845 1245696 R similar to ref|YP_001128553.1| hypothetical protein SpyM50998 [Streptococcus pyogenes str. Manfredo]; hypothetical protein complement(1244845..1245696) Streptococcus equi subsp. zooepidemicus MGCS10565 6760432 YP_002123569.1 CDS Sez_1216 NC_011134.1 1247140 1247928 D similar to ref|YP_598485.1| CobB/CobQ-like glutamine amidotransferase domain [Streptococcus pyogenes MGAS10270]; cobyric acid synthase 1247140..1247928 Streptococcus equi subsp. zooepidemicus MGCS10565 6760426 YP_002123570.1 CDS lplA NC_011134.1 1248384 1249373 R similar to ref|NP_269204.1| lipoate-protein ligase [Streptococcus pyogenes M1 GAS]; Catalyzes both the ATP-dependent activation of lipoate to lipoyl-AMP and the transfer of the activated lipoyl on the lipoate-dependent enzymes. Creates an amide linkage that joins the free carboxyl group of lipoic acid to the epsilon-amino group of a specific lysine residue in lipoyl domain of apoproteins.; lipoate-protein ligase A LplA complement(1248384..1249373) Streptococcus equi subsp. zooepidemicus MGCS10565 6760424 YP_002123571.1 CDS Sez_1218 NC_011134.1 1249363 1249515 D hypothetical protein 1249363..1249515 Streptococcus equi subsp. zooepidemicus MGCS10565 6760422 YP_002123572.1 CDS lpdA NC_011134.1 1249608 1251377 R similar to ref|YP_598482.1| Dihydrolipoamide dehydrogenase [Streptococcus pyogenes MGAS10270]; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components:pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).; dihydrolipoyl dehydrogenase LpdA complement(1249608..1251377) Streptococcus equi subsp. zooepidemicus MGCS10565 6760420 YP_002123573.1 CDS acoC NC_011134.1 1251590 1252996 R similar to ref|NP_607148.1| branched-chain alpha-keto acid dehydrogenase subunit E2 [Streptococcus pyogenes MGAS8232]; The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and Co(2). It contains multiple copies of three enzymatic components: 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3).; branched-chain alpha-keto acid dehydrogenase E2 subunit complement(1251590..1252996) Streptococcus equi subsp. zooepidemicus MGCS10565 6760418 YP_002123574.1 CDS pdhB NC_011134.1 1253120 1254118 R similar to ref|NP_269200.1| acetoin dehydrogenase (TPP-dependent) beta chain [Streptococcus pyogenes M1 GAS]; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components:pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).; pyruvate dehydrogenase E1 component subunit beta PdhB complement(1253120..1254118) Streptococcus equi subsp. zooepidemicus MGCS10565 6760411 YP_002123575.1 CDS pdhA NC_011134.1 1254198 1255178 R similar to ref|NP_802454.1| acetoin dehydrogenase (TPP-dependent) alpha chain [Streptococcus pyogenes SSI-1]; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components:pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).; pyruvate dehydrogenase E1 component subunit alpha complement(1254198..1255178) Streptococcus equi subsp. zooepidemicus MGCS10565 6760408 YP_002123576.1 CDS Sez_1223 NC_011134.1 1255672 1257582 R similar to ref|YP_001128561.1| ABC transporter ATP-binding protein [Streptococcus pyogenes str. Manfredo]; Facilitated transport; ABC transporter ATP-binding protein complement(1255672..1257582) Streptococcus equi subsp. zooepidemicus MGCS10565 6760406 YP_002123577.1 CDS Sez_1224 NC_011134.1 1257693 1257980 R similar to ref|ZP_00365872.1| hypothetical protein SpyoM01000868 [Streptococcus pyogenes M49 591]; hypothetical protein complement(1257693..1257980) Streptococcus equi subsp. zooepidemicus MGCS10565 6760404 YP_002123578.1 CDS Sez_1225 NC_011134.1 1258002 1258787 R similar to ref|NP_607143.1| tributyrin esterase [Streptococcus pyogenes MGAS8232]; acetyl esterase complement(1258002..1258787) Streptococcus equi subsp. zooepidemicus MGCS10565 6760402 YP_002123579.1 CDS Sez_1226 NC_011134.1 1258893 1260554 R similar to ref|YP_060090.1| Zn-dependent hydrolase [Streptococcus pyogenes MGAS10394]; metallo-beta-lactamase family protein complement(1258893..1260554) Streptococcus equi subsp. zooepidemicus MGCS10565 6760400 YP_002123580.1 CDS Sez_1227 NC_011134.1 1260764 1261522 R similar to ref|NP_607141.1| ABC transporter (ATP-binding protein) [Streptococcus pyogenes MGAS8232]; Part of the ABC transporter complex. Responsible for energy coupling to the transport system.; ABC transporter ATP-binding protein complement(1260764..1261522) Streptococcus equi subsp. zooepidemicus MGCS10565 6760398 YP_002123581.1 CDS Sez_1228 NC_011134.1 1261519 1262010 R similar to ref|YP_602391.1| ABC transporter permease [Streptococcus pyogenes MGAS10750]; Part Of The Binding-Protein-Dependent Transport System For Ribose. Probably Responsible For The Translocation Of The Substrate Across The Membrane.; ABC transporter permease complement(1261519..1262010) Streptococcus equi subsp. zooepidemicus MGCS10565 6760396 YP_002123582.1 CDS Sez_1229 NC_011134.1 1262001 1262387 R similar to ref|ZP_00788072.1| ABC transporter, permease [Streptococcus agalactiae CJB111]; ABC transporter permease complement(1262001..1262387) Streptococcus equi subsp. zooepidemicus MGCS10565 6760394 YP_002123583.1 CDS Sez_1230 NC_011134.1 1262401 1263396 R similar to ref|YP_329889.1| ABC transporter, substrate-binding protein, [Streptococcus agalactiae A909]; ABC transporter substrate-binding protein complement(1262401..1263396) Streptococcus equi subsp. zooepidemicus MGCS10565 6760391 YP_002123584.1 CDS Sez_1231 NC_011134.1 1263502 1263684 D hypothetical protein 1263502..1263684 Streptococcus equi subsp. zooepidemicus MGCS10565 6760390 YP_002123585.1 CDS fbp NC_011134.1 1263681 1265417 D similar to ref|YP_280188.1| fibrinogen-binding protein [Streptococcus pyogenes MGAS6180]; adhesin, lacks a canonical Sec pathway amino terminal secretion-signal peptide.; fibronectin/fibrinogen-binding protein Fbp-like 1263681..1265417 Streptococcus equi subsp. zooepidemicus MGCS10565 6760388 YP_002123586.1 CDS Sez_1233 NC_011134.1 1265505 1266743 R similar to ref|YP_282102.1| tetratricopeptide repeat family protein [Streptococcus pyogenes MGAS5005]; hypothetical protein complement(1265505..1266743) Streptococcus equi subsp. zooepidemicus MGCS10565 6760386 YP_002123587.1 CDS Sez_1234 NC_011134.1 1266733 1267914 R similar to ref|YP_602385.1| hypothetical membrane spanning protein [Streptococcus pyogenes MGAS10750]; hypothetical protein complement(1266733..1267914) Streptococcus equi subsp. zooepidemicus MGCS10565 6760384 YP_002123588.1 CDS mutT NC_011134.1 1267977 1268453 R similar to ref|NP_664453.1| dGTP pyrophosphohydrolase [Streptococcus pyogenes MGAS315]; Involved in the DNA repair system to avoid A.T to G.C transversions. Degrades 8-oxo-dGTP to the monophosphate, but is also active on all of the nucleoside triphosphates.; mutator protein MutT complement(1267977..1268453) Streptococcus equi subsp. zooepidemicus MGCS10565 6761252 YP_002123589.1 CDS rmlB NC_011134.1 1268631 1269677 R similar to pdb|1KEP|A Chain A, the crystal structure of dTDP-D-glucose 4,6-dehydratase (RmlB) from Streptococcus suis with dTDP-xylose bound; Catalysis of the reaction: dTDP-glucose = dTDP-4-dehydro-6-deoxy-D-glucose + H2O.; dTDP-glucose 4,6-dehydratase RmlB complement(1268631..1269677) Streptococcus equi subsp. zooepidemicus MGCS10565 6760382 YP_002123590.1 CDS rmlC NC_011134.1 1269924 1270466 R similar to ref|NP_688208.1| dTDP-4-dehydrorhamnose 3,5-epimerase [Streptococcus agalactiae 2603V/R]; Catalysis of the reaction: dTDP-4-dehydro-6-deoxy-D-glucose = dTDP-4-dehydro-6-deoxy-L-mannose.; dTDP-4-Keto-6-Deoxyglucose-3 5-epimerase RmlC complement(1269924..1270466) Streptococcus equi subsp. zooepidemicus MGCS10565 6760379 YP_002123591.1 CDS rmlA NC_011134.1 1270466 1271335 R similar to ref|YP_280182.1| glucose-1-phosphate thymidylyltransferase [Streptococcus pyogenes MGAS6180]; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.; glucose-1-phosphate thymidylyltransferase complement(1270466..1271335) Streptococcus equi subsp. zooepidemicus MGCS10565 6760376 YP_002123592.1 CDS Sez_1239 NC_011134.1 1271392 1272537 R similar to ref|YP_596523.1| glycine/D-amino acid oxidases family [Streptococcus pyogenes MGAS9429]; glycine/D-amino acid oxidases family complement(1271392..1272537) Streptococcus equi subsp. zooepidemicus MGCS10565 6760374 YP_002123593.1 CDS Sez_1240 NC_011134.1 1272556 1273344 R similar to ref|YP_001128625.1| NIF3 (NGG1p interacting factor 3) family protein [Streptococcus pyogenes str. Manfredo]; hypothetical protein complement(1272556..1273344) Streptococcus equi subsp. zooepidemicus MGCS10565 6761006 YP_002123594.1 CDS Sez_1241 NC_011134.1 1273334 1274020 R similar to ref|NP_269124.1| hypothetical protein SPy_0930 [Streptococcus pyogenes M1 GAS]; tRNA-m1A22 methylase complement(1273334..1274020) Streptococcus equi subsp. zooepidemicus MGCS10565 6760373 YP_002123595.1 CDS Sez_1242 NC_011134.1 1274094 1274756 R similar to ref|YP_598398.1| Endonuclease III [Streptococcus pyogenes MGAS10270]; Has both an apurinic and/or apyrimidinic endonuclease activity and a DNA N-glycosylase activity. Incises damaged DNA at cytosines, thymines and guanines. Acts on a damaged strand, 5' from the damaged site. Required for the repair of both oxidative DNA damage and spontaneous mutagenic lesions.; endonuclease III complement(1274094..1274756) Streptococcus equi subsp. zooepidemicus MGCS10565 6760371 YP_002123596.1 CDS dnaD NC_011134.1 1274756 1275496 R similar to ref|YP_598397.1| DNA replication protein dnaD [Streptococcus pyogenes MGAS10270]; component of primosome involved in the initiation of DNA replication.; DNA replication protein DnaD complement(1274756..1275496) Streptococcus equi subsp. zooepidemicus MGCS10565 6760369 YP_002123597.1 CDS apt NC_011134.1 1275500 1276018 R catalyzes a salvage reaction resulting in the formation of AMP which is metabolically less costly than a de novo synthesis; adenine phosphoribosyltransferase complement(1275500..1276018) Streptococcus equi subsp. zooepidemicus MGCS10565 6761257 YP_002123598.1 CDS Sez_1245 NC_011134.1 1276098 1276466 R similar to ref|YP_001035269.1| hypothetical protein SSA_1320 [Streptococcus sanguinis SK36]; hypothetical protein complement(1276098..1276466) Streptococcus equi subsp. zooepidemicus MGCS10565 6760367 YP_002123599.1 CDS recJ NC_011134.1 1276475 1278685 R similar to ref|YP_598395.1| Single-stranded-DNA-specific exonuclease recJ [Streptococcus pyogenes MGAS10270]; Single-stranded-DNA-specific exonuclease. Required for many types of recombinational events, although the stringency of the requirement for recJ appears to vary with the type of recombinational event monitored and the other recombination gene products which are available.; single-stranded-DNA-specific exonuclease RecJ complement(1276475..1278685) Streptococcus equi subsp. zooepidemicus MGCS10565 6760986 YP_002123600.1 CDS Sez_1247 NC_011134.1 1278682 1279446 R similar to ref|NP_664442.1| oxidoreductase, short chain dehydrogenase/reductase family [Streptococcus pyogenes MGAS315]; short chain dehydrogenase complement(1278682..1279446) Streptococcus equi subsp. zooepidemicus MGCS10565 6761134 YP_002123601.1 CDS rnz NC_011134.1 1279446 1280375 R member of metallo-beta-lactamase family; the purified enzyme from Escherichia coli forms dimeric zinc phosphodiesterase; in Bacillus subtilis this protein is a 3'-tRNA processing endoribonuclease and is essential while in Escherichia coli it is not; associates with two zinc ions; ribonuclease Z complement(1279446..1280375) Streptococcus equi subsp. zooepidemicus MGCS10565 6761262 YP_002123602.1 CDS Sez_1249 NC_011134.1 1280390 1281025 R similar to ref|YP_280172.1| cystathionine beta-lyase [Streptococcus pyogenes MGAS6180]; hypothetical protein complement(1280390..1281025) Streptococcus equi subsp. zooepidemicus MGCS10565 6760366 YP_002123603.1 CDS hflX NC_011134.1 1281018 1282256 R similar to ref|NP_607120.1| GTP-binding protein [Streptococcus pyogenes MGAS8232]; GTP-binding protein HflX complement(1281018..1282256) Streptococcus equi subsp. zooepidemicus MGCS10565 6761095 YP_002123604.1 CDS miaA NC_011134.1 1282341 1283231 R IPP transferase; isopentenyltransferase; involved in tRNA modification; in Escherichia coli this enzyme catalyzes the addition of a delta2-isopentenyl group from dimethylallyl diphosphate to the N6-nitrogen of adenosine adjacent to the anticodon of tRNA species that read codons starting with uracil; further tRNA modifications may occur; mutations in miaA result in defects in translation efficiency and fidelity; tRNA delta(2)-isopentenylpyrophosphate transferase complement(1282341..1283231) Streptococcus equi subsp. zooepidemicus MGCS10565 6761197 YP_002123605.1 CDS Sez_1252 NC_011134.1 1283358 1283540 D similar to ref|YP_602309.1| hypothetical protein MGAS10750_Spy0815 [Streptococcus pyogenes MGAS10750]; hypothetical protein 1283358..1283540 Streptococcus equi subsp. zooepidemicus MGCS10565 6761322 YP_002123606.1 CDS Sez_1253 NC_011134.1 1283696 1284343 R similar to ref|YP_895632.1| possible uridine kinase [Bacillus thuringiensis str. Al Hakam]; hypothetical protein complement(1283696..1284343) Streptococcus equi subsp. zooepidemicus MGCS10565 6761030 YP_002123607.1 CDS malP NC_011134.1 1284510 1286774 R similar to ref|YP_280504.1| glycogen phosphorylase [Streptococcus pyogenes MGAS6180]; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.; maltodextrin phosphorylase complement(1284510..1286774) Streptococcus equi subsp. zooepidemicus MGCS10565 6761164 YP_002123608.1 CDS malQ NC_011134.1 1286800 1288275 R amylomaltase; acts to release glucose from maltodextrins; 4-alpha-glucanotransferase complement(1286800..1288275) Streptococcus equi subsp. zooepidemicus MGCS10565 6761024 YP_002123609.1 CDS malR NC_011134.1 1288507 1289529 R similar to ref|YP_596834.1| transcriptional regulator, LacI family [Streptococcus pyogenes MGAS9429]; Transcriptional repressor of the malA gene for maltase.; maltose operon transcriptional repressor MalR complement(1288507..1289529) Streptococcus equi subsp. zooepidemicus MGCS10565 6760998 YP_002123610.1 CDS malE NC_011134.1 1289778 1291031 D similar to ref|YP_596835.1| maltose/maltodextrin-binding protein [Streptococcus pyogenes MGAS9429]; Binding protein for maltose and maltodextrin; involved in its cellular uptake.; maltose/maltodextrin ABC transporter substrate binding periplasmic protein MalE 1289778..1291031 Streptococcus equi subsp. zooepidemicus MGCS10565 6761297 YP_002123611.1 CDS malF NC_011134.1 1291331 1292692 D similar to ref|NP_269422.1| maltose/maltodextrin ABC transport system (permease) [Streptococcus pyogenes M1 GAS]; Part of the binding-protein-dependent transport system for maltodextrin; probably responsible for the translocation of the substrate across the membrane.; maltodextrin ABC transporter permease 1291331..1292692 Streptococcus equi subsp. zooepidemicus MGCS10565 6761186 YP_002123612.1 CDS malG NC_011134.1 1292692 1293528 D similar to ref|NP_269423.1| maltose/maltodextrin ABC transport system (permease) [Streptococcus pyogenes M1 GAS]; Part of the binding-protein-dependent transport system for maltodextrin; probably responsible for the translocation of the substrate across the membrane.; maltose ABC transporter permease 1292692..1293528 Streptococcus equi subsp. zooepidemicus MGCS10565 6761067 YP_002123613.1 CDS malA NC_011134.1 1293602 1294432 R similar to ref|YP_598727.1| Maltodextrose utilization protein malA [Streptococcus pyogenes MGAS10270]; Has a role in maltotetraose utilization.; maltodextrose utilization protein MalA complement(1293602..1294432) Streptococcus equi subsp. zooepidemicus MGCS10565 6761306 YP_002123614.1 CDS malC NC_011134.1 1295315 1296619 R similar to ref|NP_269427.1| maltodextrin transport system permease [Streptococcus pyogenes M1 GAS]; Part of the binding-protein-dependent transport system for maltodextrin; probably responsible for the translocation of the substrate across the membrane.; maltodextrin ABC transporter permease complement(1295315..1296619) Streptococcus equi subsp. zooepidemicus MGCS10565 6760360 YP_002123615.1 CDS amyA NC_011134.1 1296695 1298854 R similar to ref|YP_280514.1| alpha-amylase [Streptococcus pyogenes MGAS6180]; Degrades starch to alpha-, beta-, and gamma- cyclodextrins, as well as linear sugars.; cyclomaltodextrin glucanotransferase complement(1296695..1298854) Streptococcus equi subsp. zooepidemicus MGCS10565 6760358 YP_002123616.1 CDS amyB NC_011134.1 1298856 1300556 R similar to ref|YP_598731.1| Neopullulanase / Cyclomaltodextrinase / Maltogenic alpha-amylase [Streptococcus pyogenes MGAS10270]; Hydrolyzes cyclodextrins. Can also act on linear maltodextrins, with the exception of maltose.; cyclomaltodextrinase complement(1298856..1300556) Streptococcus equi subsp. zooepidemicus MGCS10565 6760355 YP_002123617.1 CDS malX NC_011134.1 1300729 1301988 R similar to ref|YP_280516.1| maltose/maltodextrin-binding protein [Streptococcus pyogenes MGAS6180]; Binding protein for maltose and maltodextrin; involved in its cellular uptake.; maltose/maltodextrin-binding lipoprotein precursor MalX complement(1300729..1301988) Streptococcus equi subsp. zooepidemicus MGCS10565 6760353 YP_002123618.1 CDS Sez_1267 NC_011134.1 1302529 1303497 R similar to ref|NP_269431.1| esterase [Streptococcus pyogenes M1 GAS]; This protein removes the N-acetyl group from bialaphos as one of the final steps of the bialaphos biosynthetic pathway.; esterase complement(1302529..1303497) Streptococcus equi subsp. zooepidemicus MGCS10565 6760825 YP_002123619.1 CDS dltD NC_011134.1 1303537 1304790 R similar to ref|NP_664795.1| hypothetical protein DltD [Streptococcus pyogenes MGAS315]; Could be responsible for the transfer of D-alanine residues from D-Ala-undecaprenol phosphate to the poly(glycerophosphate) chains.; poly(glycerophosphate chain) D-alanine transfer protein DltD complement(1303537..1304790) Streptococcus equi subsp. zooepidemicus MGCS10565 6760808 YP_002123620.1 CDS dltC NC_011134.1 1304783 1305022 R D-alanyl carrier protein subunit; involved in the incorporation of D-alanine into membrane-associated D-alanyl-lipoteichoic acid; D-alanyl carrier protein is the acceptor of activated D-alanine which it donates to a membrane acceptor(D-alanyl transferase) for incorporation into membrane lipoteichoic acid; D-alanine--poly(phosphoribitol) ligase subunit 2 complement(1304783..1305022) Streptococcus equi subsp. zooepidemicus MGCS10565 6760572 YP_002123621.1 CDS dltB NC_011134.1 1305040 1306299 R similar to ref|YP_060360.1| DltB [Streptococcus pyogenes MGAS10394]; Could be involved in the transport of activated D- alanine through the membrane.; D-alanyl transfer protein DltB complement(1305040..1306299) Streptococcus equi subsp. zooepidemicus MGCS10565 6760835 YP_002123622.1 CDS dltA NC_011134.1 1306296 1307834 R transfers D-alanine to the D-alanyl carrier protein during the incorporation of D-alanine into lipoteichoic acid; D-alanine--poly(phosphoribitol) ligase subunit 1 complement(1306296..1307834) Streptococcus equi subsp. zooepidemicus MGCS10565 6760963 YP_002123623.1 CDS Sez_1272 NC_011134.1 1307846 1307989 R similar to ref|NP_607430.1| hypothetical protein spyM18_1325 [Streptococcus pyogenes MGAS8232]; hypothetical protein complement(1307846..1307989) Streptococcus equi subsp. zooepidemicus MGCS10565 6762346 YP_002123624.1 CDS uvrB NC_011134.1 1308328 1310319 R The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion; excinuclease ABC subunit B complement(1308328..1310319) Streptococcus equi subsp. zooepidemicus MGCS10565 6760735 YP_002123625.1 CDS glnP NC_011134.1 1310535 1312676 D similar to ref|YP_001128349.1| glutamine ABC transporter,glutamine-binding protein/permease [Streptococcus pyogenes str. Manfredo]; Part of the binding-protein-dependent transport system for glutamine; probably responsible for the translocation of the substrate across the membrane.; glutamine ABC transporter, glutamine-binding protein/permease GlnP 1310535..1312676 Streptococcus equi subsp. zooepidemicus MGCS10565 6762353 YP_002123626.1 CDS glnQ NC_011134.1 1312676 1313416 D similar to ref|YP_280526.1| glutamine transport ATP-binding protein [Streptococcus pyogenes MGAS6180]; Probably part of a binding-protein-dependent transport system for an amino acid. Probably responsible for energy coupling to the transport system.; glutamine transport ATP-binding protein GlnQ 1312676..1313416 Streptococcus equi subsp. zooepidemicus MGCS10565 6762328 YP_002123627.1 CDS Sez_1276 NC_011134.1 1313405 1313569 R hypothetical protein complement(1313405..1313569) Streptococcus equi subsp. zooepidemicus MGCS10565 6762325 YP_002123628.1 CDS Sez_1277 NC_011134.1 1313573 1313725 R similar to ref|NP_607434.1| hypothetical protein spyM18_1329 [Streptococcus pyogenes MGAS8232]; hypothetical protein complement(1313573..1313725) Streptococcus equi subsp. zooepidemicus MGCS10565 6762345 YP_002123629.1 CDS celB NC_011134.1 1313722 1315101 R similar to ref|YP_282442.1| PTS system, cellobiose-specific IIC component [Streptococcus pyogenes MGAS5005]; The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. This system is involved in cellobiose transport.; cellobiose permease IIC component CelB complement(1313722..1315101) Streptococcus equi subsp. zooepidemicus MGCS10565 6762337 YP_002123630.1 CDS Sez_1279 NC_011134.1 1315176 1315613 R similar to ref|YP_060367.1| hypothetical protein M6_Spy1049 [Streptococcus pyogenes MGAS10394]; hypothetical protein complement(1315176..1315613) Streptococcus equi subsp. zooepidemicus MGCS10565 6762334 YP_002123631.1 CDS celA NC_011134.1 1315610 1315945 R similar to ref|NP_269440.1| PTS enzyme III [Streptococcus pyogenes M1 GAS]; The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. This system is involved in lichenan transport.; cellobiose-specific phosphotransferase enzyme IIA component complement(1315610..1315945) Streptococcus equi subsp. zooepidemicus MGCS10565 6762309 YP_002123632.1 CDS Sez_1281 NC_011134.1 1315942 1316259 R similar to ref|YP_001128343.1| lactose/cellobiose-specific phosphotransferase system (PTS), IIB component [Streptococcus pyogenes str. Manfredo]; The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active-transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. This system is involved in cellobiose transport.; cellobiose-specific phosphotransferase enzyme IIB component complement(1315942..1316259) Streptococcus equi subsp. zooepidemicus MGCS10565 6762319 YP_002123633.1 CDS Sez_1282 NC_011134.1 1316273 1318270 R similar to gb|AAX72177.1| transcription antiterminator, BglG family [Streptococcus pyogenes MGAS6180]; Positive regulator of the licABCH operon.; BglG family transcription antiterminator/PTS system transporter subunit IIA complement(1316273..1318270) Streptococcus equi subsp. zooepidemicus MGCS10565 6762294 YP_002123634.1 CDS Sez_1283 NC_011134.1 1318373 1319470 R similar to ref|YP_060371.1| outer surface protein [Streptococcus pyogenes MGAS10394]; outer membrane protein complement(1318373..1319470) Streptococcus equi subsp. zooepidemicus MGCS10565 6762312 YP_002123635.1 CDS pnuC NC_011134.1 1321204 1321920 D similar to ref|YP_001128339.1| nicotinamide mononucleotide transporter [Streptococcus pyogenes str. Manfredo]; ribosyl nicotinamide transporter PnuC-like 1321204..1321920 Streptococcus equi subsp. zooepidemicus MGCS10565 6762303 YP_002123636.1 CDS Sez_1287 NC_011134.1 1321973 1322131 R similar to ref|NP_269446.1| hypothetical protein SPy_1332 [Streptococcus pyogenes M1 GAS]; hypothetical protein complement(1321973..1322131) Streptococcus equi subsp. zooepidemicus MGCS10565 6762299 YP_002123637.1 CDS obgE NC_011134.1 1322246 1323553 R essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication; GTPase ObgE complement(1322246..1323553) Streptococcus equi subsp. zooepidemicus MGCS10565 6762296 YP_002123638.1 CDS pepS NC_011134.1 1324001 1325296 D similar to ref|ZP_00790289.1| aminopeptidase PepS [Streptococcus agalactiae 515]; Exhibits a high specificity towards peptides possessing arginine or aromatic amino acids at the N-terminus. Could be involved both in bacterial growth by supplying amino acids.; aminopeptidase 1324001..1325296 Streptococcus equi subsp. zooepidemicus MGCS10565 6762286 YP_002123639.1 CDS rsuA NC_011134.1 1325320 1326033 R similar to ref|YP_001201503.1| 16S rRNA uridine-516 pseudouridylate synthase and related Pseudouridylate synthase [Streptococcus suis 98HAH33]; Responsible for synthesis of pseudouridine from uracil- 516 in 16S ribosomal RNA.; ribosomal small subunit pseudouridine synthase A RsuA complement(1325320..1326033) Streptococcus equi subsp. zooepidemicus MGCS10565 6762289 YP_002123640.1 CDS Sez_1291 NC_011134.1 1326198 1326557 D similar to ref|NP_269451.1| hypothetical protein SPy_1339 [Streptococcus pyogenes M1 GAS]; dihydrolipoamide acyltransferase 1326198..1326557 Streptococcus equi subsp. zooepidemicus MGCS10565 6762284 YP_002123641.1 CDS Sez_1292 NC_011134.1 1326648 1327871 R similar to ref|YP_001128328.1| major facilitator superfamily protein [Streptococcus pyogenes str. Manfredo]; major facilitator family transporter complement(1326648..1327871) Streptococcus equi subsp. zooepidemicus MGCS10565 6762265 YP_002123642.1 CDS Sez_1293 NC_011134.1 1328231 1329715 D similar to ref|NP_664825.1| ATP-dependent Zn protease [Streptococcus pyogenes MGAS315]; hypothetical protein 1328231..1329715 Streptococcus equi subsp. zooepidemicus MGCS10565 6762277 YP_002123643.1 CDS paaI NC_011134.1 1329771 1330175 R similar to ref|YP_596870.1| thioesterase superfamily protein [Streptococcus pyogenes MGAS9429]; Phenylacetic acid aerobic catabolism.; phenylacetic acid degradation protein PaaI complement(1329771..1330175) Streptococcus equi subsp. zooepidemicus MGCS10565 6762271 YP_002123644.1 CDS Sez_1295 NC_011134.1 1330703 1330861 R hypothetical protein complement(1330703..1330861) Streptococcus equi subsp. zooepidemicus MGCS10565 6762268 YP_002123645.1 CDS Sez_1296 NC_011134.1 1331086 1331622 R similar to ref|YP_319963.1| hypothetical protein Ava_B0060 [Anabaena variabilis ATCC 29413]; GNAT family acetyltransferase complement(1331086..1331622) Streptococcus equi subsp. zooepidemicus MGCS10565 6762263 YP_002123646.1 CDS Sez_1297 NC_011134.1 1331818 1332456 R similar to ref|NP_664256.1| hypothetical protein SpyM3_0452 [Streptococcus pyogenes MGAS315]; Displays high phosphatase activity toward erythrose 4- phosphate, fructose 6-phosphate, 2-deoxyglucose 6-phosphate, and mannose 6-phosphate. May have a role in the intracellular metabolism of many phosphorylated carbohydrates.; phosphorylated carbohydrates phosphatase complement(1331818..1332456) Streptococcus equi subsp. zooepidemicus MGCS10565 6762260 YP_002123647.1 CDS Sez_1298 NC_011134.1 1332644 1333045 D similar to emb|CAG09263.1| unnamed protein product [Tetraodon nigroviridis]; hypothetical protein 1332644..1333045 Streptococcus equi subsp. zooepidemicus MGCS10565 6762258 YP_002123648.1 CDS hylB NC_011134.1 1333221 1336412 R similar to gb|ABV69920.1| hyaluronidase [Streptococcus equi subsp. zooepidemicus]; hyaluronate lyase precursor HylB complement(1333221..1336412) Streptococcus equi subsp. zooepidemicus MGCS10565 6762255 YP_002123649.1 CDS kdgA NC_011134.1 1336452 1337081 R catalyzes the formation of pyruvate and glyoxylate from 4-hydroxy-2-oxoglutarate; or pyruvate and D-glyceraldehyde 3-phosphate from 2-dehydro-3-deoxy-D-glyconate 6-phosphate; keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase complement(1336452..1337081) Streptococcus equi subsp. zooepidemicus MGCS10565 6762251 YP_002123650.1 CDS kdgK NC_011134.1 1337083 1338084 R similar to ref|YP_602039.1| 2-dehydro-3-deoxygluconokinase [Streptococcus pyogenes MGAS10750]; Catalysis of the reaction: ATP + 2-dehydro-3-deoxy-D-gluconate = ADP + beta-L-arabinose 1-phosphate.; 2-dehydro-3-deoxygluconokinase complement(1337083..1338084) Streptococcus equi subsp. zooepidemicus MGCS10565 6762245 YP_002123651.1 CDS Sez_1302 NC_011134.1 1338117 1338758 R similar to gb|ABF33585.1| Galactose-6-phosphate isomerase LacB subunit [Streptococcus pyogenes MGAS10270]; hypothetical protein complement(1338117..1338758) Streptococcus equi subsp. zooepidemicus MGCS10565 6762226 YP_002123652.1 CDS Sez_1303 NC_011134.1 1338785 1339582 R Involved in the nonphosphorylative, ketogenic oxidation of glucose and oxidizes gluconate to 5-ketogluconate; gluconate 5-dehydrogenase complement(1338785..1339582) Streptococcus equi subsp. zooepidemicus MGCS10565 6762240 YP_002123653.1 CDS agaA NC_011134.1 1339889 1340323 D similar to ref|YP_059862.1| PTS system, N-acetylgalactosamine-specific IIA component [Streptococcus pyogenes MGAS10394]; Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + sugar(out) = protein histidine + sugar phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport.; PTS system N-acetylgalactosamine- and galactosamine-specific transporter subunit IIA AgaA 1339889..1340323 Streptococcus equi subsp. zooepidemicus MGCS10565 6762238 YP_002123654.1 CDS Sez_1305 NC_011134.1 1340323 1341522 D similar to ref|YP_596245.1| unsaturated glucuronyl hydrolase [Streptococcus pyogenes MGAS9429]; Catalyzes the hydrolysis of oligosaccharides with unsaturated glucuronyl residues at the nonreducing terminal, to a sugar or an amino sugar, and an unsaturated D-glucuronic acid (GlcA), which is nonenzymatically converted immediately to alpha- keto acid.; unsaturated glucuronyl hydrolase 1340323..1341522 Streptococcus equi subsp. zooepidemicus MGCS10565 6762236 YP_002123655.1 CDS agaB NC_011134.1 1341568 1342056 D similar to ref|YP_279969.1| PTS system, N-acetylgalactosamine-specific IIB component [Streptococcus pyogenes MGAS6180]; The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. This system is involved in N-acetylgalactosamine transport.; N-acetylgalactosamine-specific phosphotransferase enzyme IIB component AgaB 1341568..1342056 Streptococcus equi subsp. zooepidemicus MGCS10565 6762234 YP_002123656.1 CDS agaC NC_011134.1 1342134 1342850 D similar to ref|NP_268877.1| PTS dependent N-acetyl-galactosamine-IIC component [Streptococcus pyogenes M1 GAS]; The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. This system is involved in N-acetylgalactosamine transport.; N-acetylgalactosamine permease IIC component AgaC 1342134..1342850 Streptococcus equi subsp. zooepidemicus MGCS10565 6762224 YP_002123657.1 CDS agaD NC_011134.1 1342804 1343658 D similar to ref|YP_059858.1| PTS system, N-acetylgalactosamine-specific IID component [Streptococcus pyogenes MGAS10394]; The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. This system is involved in N-acetylgalactosamine transport.; N-acetylgalactosamine permease IID component AgaD 1342804..1343658 Streptococcus equi subsp. zooepidemicus MGCS10565 6762218 YP_002123658.1 CDS Sez_1309 NC_011134.1 1344058 1345059 D similar to ref|YP_602030.1| Transcriptional regulator, LacI family [Streptococcus pyogenes MGAS10750]; Sugar-binding transcriptional regulator.; LacI family transcriptional regulator 1344058..1345059 Streptococcus equi subsp. zooepidemicus MGCS10565 6762195 YP_002123659.1 CDS Sez_1310 NC_011134.1 1345635 1345916 D similar to ref|YP_001451052.1| hypothetical protein SGO_1783 [Streptococcus gordonii str. Challis substr. CH1]; hypothetical protein 1345635..1345916 Streptococcus equi subsp. zooepidemicus MGCS10565 6762188 YP_002123660.1 CDS Sez_1311 NC_011134.1 1345913 1346272 D similar to ref|YP_001035341.1| hypothetical protein SSA_1393 [Streptococcus sanguinis SK36]; hypothetical protein 1345913..1346272 Streptococcus equi subsp. zooepidemicus MGCS10565 6762212 YP_002123661.1 CDS Sez_1312 NC_011134.1 1346263 1347669 D similar to ref|YP_001035340.1| hypothetical protein SSA_1392 [Streptococcus sanguinis SK36]; hypothetical protein 1346263..1347669 Streptococcus equi subsp. zooepidemicus MGCS10565 6762206 YP_002123662.1 CDS Sez_1313 NC_011134.1 1347693 1348172 D similar to ref|YP_001035338.1| hypothetical protein SSA_1390 [Streptococcus sanguinis SK36]; hypothetical protein 1347693..1348172 Streptococcus equi subsp. zooepidemicus MGCS10565 6762204 YP_002123663.1 CDS Sez_1314 NC_011134.1 1348371 1351052 R similar to ref|NP_664244.1| calcium transporter [Streptococcus pyogenes MGAS315]; Could possibly be a calcium ATPase; cation-transporting ATPase complement(1348371..1351052) Streptococcus equi subsp. zooepidemicus MGCS10565 6762153 YP_002123664.1 CDS Sez_1315 NC_011134.1 1351402 1351788 R similar to ref|YP_602028.1| hypothetical cytosolic protein [Streptococcus pyogenes MGAS10750]; hypothetical protein complement(1351402..1351788) Streptococcus equi subsp. zooepidemicus MGCS10565 6762197 YP_002123665.1 CDS Sez_1316 NC_011134.1 1351869 1353170 D similar to ref|YP_596237.1| dGTP triphosphohydrolase [Streptococcus pyogenes MGAS9429]; Catalysis of the reaction: dGTP + H2O = deoxyguanosine + triphosphate.; deoxyguanosinetriphosphate triphosphohydrolase 1351869..1353170 Streptococcus equi subsp. zooepidemicus MGCS10565 6762171 YP_002123666.1 CDS Sez_1317 NC_011134.1 1353167 1353358 R hypothetical protein complement(1353167..1353358) Streptococcus equi subsp. zooepidemicus MGCS10565 6762158 YP_002123667.1 CDS Sez_1318 NC_011134.1 1353382 1354191 D similar to ref|ZP_00366263.1| COG0561: Predicted hydrolases of the HAD superfamily [Streptococcus pyogenes M49 591]; hydrolase HAD family 1353382..1354191 Streptococcus equi subsp. zooepidemicus MGCS10565 6762172 YP_002123668.1 CDS murM NC_011134.1 1354191 1355405 D similar to ref|YP_598114.1| UDP-N-acetylmuramoylpentapeptide-lysine N(6)-alanyltransferase / UDP-N-acetylmuramoylpentapeptide-lysine N(6)-seryltransferase [Streptococcus pyogenes MGAS10270]; peptidoglycan branched peptide synthesis protein, serine/alanine adding enzyme MurM 1354191..1355405 Streptococcus equi subsp. zooepidemicus MGCS10565 6762169 YP_002123669.1 CDS murN NC_011134.1 1355405 1356640 D similar to ref|YP_820103.1| Peptidoglycan interpeptide bridge formation enzyme [Streptococcus thermophilus LMD-9]; MurN protein 1355405..1356640 Streptococcus equi subsp. zooepidemicus MGCS10565 6762151 YP_002123670.1 CDS tpiA NC_011134.1 1356953 1357711 R Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate; triosephosphate isomerase complement(1356953..1357711) Streptococcus equi subsp. zooepidemicus MGCS10565 6762150 YP_002123671.1 CDS tuf NC_011134.1 1357977 1359173 R EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu; elongation factor Tu complement(1357977..1359173) Streptococcus equi subsp. zooepidemicus MGCS10565 6762143 YP_002123672.1 CDS Sez_1323 NC_011134.1 1360122 1363268 D similar to gb|AAN18292.1| immunoreactive protein Se117 [Streptococcus equi]; Unknown, may be a viral enhancing factor (an enhancin); 1st 700aa are virtually identical to immunoreactive protein Se117 of S. equi, and the last 300aa are similar to a chitin-binding protein of B. thuringiensis.; hypothetical protein 1360122..1363268 Streptococcus equi subsp. zooepidemicus MGCS10565 6762133 YP_002123673.1 CDS Sez_1324 NC_011134.1 1363558 1364646 R similar to ref|ZP_00786125.1| conserved hypothetical protein [Streptococcus agalactiae COH1]; hypothetical protein complement(1363558..1364646) Streptococcus equi subsp. zooepidemicus MGCS10565 6762132 YP_002123674.1 CDS Sez_1325 NC_011134.1 1364630 1365100 R similar to gb|AAN18293.1| Se18.7 [Streptococcus equi]; DNA-directed RNA polymerase specialized sigma subunit; RNA polymerase ECF-type sigma factor complement(1364630..1365100) Streptococcus equi subsp. zooepidemicus MGCS10565 6762107 YP_002123675.1 CDS Sez_1326 NC_011134.1 1365457 1365666 D similar to ref|YP_001039946.1| hypothetical protein phi3396_59 [Streptococcus phage phi3396]; Possibly involved in regulation has an HTH DNA-binding domain and shares similarity with phage cI transcriptional regulator.; hypothetical protein 1365457..1365666 Streptococcus equi subsp. zooepidemicus MGCS10565 6762103 YP_002123676.1 CDS csn2 NC_011134.1 1367462 1368136 R similar to ref|YP_602418.1| hypothetical protein MGAS10750_Spy0924 [Streptococcus pyogenes MGAS10750]; ly involved in mediating bacterial immunity to mobile genetic elements such as phages and ICEs.; CRISPR associated protein Csn2 complement(1367462..1368136) Streptococcus equi subsp. zooepidemicus MGCS10565 6762101 YP_002123677.1 CDS cas2 NC_011134.1 1368129 1368452 R similar to ref|NP_269217.1| hypothetical protein SPy_1048 [Streptococcus pyogenes M1 GAS]; ly involved in mediating bacterial immunity to mobile genetic elements such as phages and ICEs.; CRISPR assocaiated protein Cas2 complement(1368129..1368452) Streptococcus equi subsp. zooepidemicus MGCS10565 6762102 YP_002123678.1 CDS cas1 NC_011134.1 1368470 1369339 R similar to ref|NP_721763.1| hypothetical protein SMU.1404c [Streptococcus mutans UA159]; ly involved in mediating bacterial immunity to mobile genetic elements such as phages and ICEs.; CRISPR-associated protein Cas1 complement(1368470..1369339) Streptococcus equi subsp. zooepidemicus MGCS10565 6762122 YP_002123679.1 CDS csn1 NC_011134.1 1369339 1373385 R similar to ref|YP_282132.1| hypothetical cytosolic protein [Streptococcus pyogenes MGAS5005]; ly involved in mediating bacterial immunity to mobile genetic elements such as phages and ICEs.; CRISPR-Associated Protein Csn1 complement(1369339..1373385) Streptococcus equi subsp. zooepidemicus MGCS10565 6762114 YP_002123680.1 CDS Sez_1331 NC_011134.1 1373899 1374060 R similar to ref|YP_012695.1| hypothetical protein LMOf2365_0084 [Listeria monocytogenes str. 4b F2365]; Possible undefined CRISPR-associated protein.; hypothetical protein complement(1373899..1374060) Streptococcus equi subsp. zooepidemicus MGCS10565 6762110 YP_002123681.1 CDS Sez_1332 NC_011134.1 1374223 1374885 R similar to ref|YP_012695.1| hypothetical protein LMOf2365_0084 [Listeria monocytogenes str. 4b F2365]; Lmo0066 homolog within ESAT-6 gene cluster, similarity to ADP-ribosylating toxins.; hypothetical protein complement(1374223..1374885) Streptococcus equi subsp. zooepidemicus MGCS10565 6762100 YP_002123682.1 CDS Sez_1333 NC_011134.1 1374915 1375610 R similar to ref|YP_001035282.1| hypothetical protein SSA_1333 [Streptococcus sanguinis SK36]; hypothetical protein complement(1374915..1375610) Streptococcus equi subsp. zooepidemicus MGCS10565 6762094 YP_002123683.1 CDS Sez_1334 NC_011134.1 1375676 1376896 R similar to ref|ZP_02093553.1| hypothetical protein PEPMIC_00304 [Peptostreptococcus micros ATCC 33270]; hypothetical protein complement(1375676..1376896) Streptococcus equi subsp. zooepidemicus MGCS10565 6762088 YP_002123684.1 CDS Sez_1335 NC_011134.1 1376966 1377388 R similar to ref|YP_820678.1| hypothetical protein STER_1302 [Streptococcus thermophilus LMD-9]; hypothetical protein complement(1376966..1377388) Streptococcus equi subsp. zooepidemicus MGCS10565 6762086 YP_002123685.1 CDS Sez_1336 NC_011134.1 1377578 1377982 R similar to ref|XP_001303410.1| Gene info Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase [Trichomonas vaginalis G3]; hypothetical protein complement(1377578..1377982) Streptococcus equi subsp. zooepidemicus MGCS10565 6762083 YP_002123686.1 CDS Sez_1337 NC_011134.1 1377991 1379166 R similar to ref|ZP_02093553.1| hypothetical protein PEPMIC_00304 [Peptostreptococcus micros ATCC 33270]; Lmo0066 homolog within ESAT-6 gene cluster, similarity to ADP-ribosylating toxins.; hypothetical protein complement(1377991..1379166) Streptococcus equi subsp. zooepidemicus MGCS10565 6762078 YP_002123687.1 CDS Sez_1338 NC_011134.1 1379781 1380560 R similar to ref|YP_906161.1| conserved alanine and proline rich protein [Mycobacterium ulcerans Agy99]; hypothetical protein complement(1379781..1380560) Streptococcus equi subsp. zooepidemicus MGCS10565 6762073 YP_002123688.1 CDS Sez_1339 NC_011134.1 1380689 1381111 R similar to gb|EDS33976.1| calpain [Culex pipiens quinquefasciatus]; Unknown, possible calpain-like cysteine proteiase.; hypothetical protein complement(1380689..1381111) Streptococcus equi subsp. zooepidemicus MGCS10565 6762071 YP_002123689.1 CDS Sez_1340 NC_011134.1 1381093 1382358 R similar to ref|ZP_02093553.1| hypothetical protein PEPMIC_00304 [Peptostreptococcus micros ATCC 33270]; hypothetical protein complement(1381093..1382358) Streptococcus equi subsp. zooepidemicus MGCS10565 6762062 YP_002123690.1 CDS Sez_1341 NC_011134.1 1382334 1383125 R similar to ref|ZP_02093553.1| hypothetical protein PEPMIC_00304 [Peptostreptococcus micros ATCC 33270]; hypothetical protein complement(1382334..1383125) Streptococcus equi subsp. zooepidemicus MGCS10565 6762040 YP_002123691.1 CDS Sez_1342 NC_011134.1 1383725 1384528 R similar to ref|NP_268574.1| transposase, IS861 [Streptococcus pyogenes M1 GAS]; transposase IS861 orfB complement(1383725..1384528) Streptococcus equi subsp. zooepidemicus MGCS10565 6762052 YP_002123692.1 CDS Sez_1343 NC_011134.1 1384552 1385067 R similar to ref|YP_602677.1| Transposase [Streptococcus pyogenes MGAS10750]; transposase IS861 orfA complement(1384552..1385067) Streptococcus equi subsp. zooepidemicus MGCS10565 6762053 YP_002123693.1 CDS Sez_1344 NC_011134.1 1385175 1386080 R similar to ref|NP_664225.1| hypothetical protein SpyM3_0421 [Streptococcus pyogenes MGAS315]; 2-haloalkanoic acid dehalogenase complement(1385175..1386080) Streptococcus equi subsp. zooepidemicus MGCS10565 6762048 YP_002123694.1 CDS Sez_1345 NC_011134.1 1386392 1387825 R similar to ref|NP_688697.1| drug resistance transporter, EmrB/QacA family [Streptococcus agalactiae 2603V/R]; Translocase that confers resistance to substances of high hydrophobicity.; multidrug resistance protein complement(1386392..1387825) Streptococcus equi subsp. zooepidemicus MGCS10565 6762032 YP_002123695.1 CDS lysS NC_011134.1 1388200 1389705 D class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1; lysyl-tRNA synthetase 1388200..1389705 Streptococcus equi subsp. zooepidemicus MGCS10565 6762043 YP_002123696.1 CDS Sez_1347 NC_011134.1 1389856 1389993 R hypothetical protein complement(1389856..1389993) Streptococcus equi subsp. zooepidemicus MGCS10565 6762035 YP_002123697.1 CDS Sez_1348 NC_011134.1 1390109 1390249 D hypothetical protein 1390109..1390249 Streptococcus equi subsp. zooepidemicus MGCS10565 6762017 YP_002123698.1 CDS Sez_1349 NC_011134.1 1391147 1391359 R similar to ref|YP_602006.1| hypothetical cytosolic protein [Streptococcus pyogenes MGAS10750]; Unknown, bacterial seryl-tRNA synthetase related.; hypothetical protein complement(1391147..1391359) Streptococcus equi subsp. zooepidemicus MGCS10565 6762024 YP_002123699.1 CDS Sez_1350 NC_011134.1 1391492 1391620 R hypothetical protein complement(1391492..1391620) Streptococcus equi subsp. zooepidemicus MGCS10565 6762011 YP_002123700.1 CDS Sez_1351 NC_011134.1 1391621 1391794 D hypothetical protein 1391621..1391794 Streptococcus equi subsp. zooepidemicus MGCS10565 6761997 YP_002123701.1 CDS Sez_1352 NC_011134.1 1391890 1393176 R similar to ref|ZP_00365935.1| COG0826: Collagenase and related proteases [Streptococcus pyogenes M49 591]; The hydrolysis of a peptide bond or bonds within a protein.; peptidase U32 complement(1391890..1393176) Streptococcus equi subsp. zooepidemicus MGCS10565 6762004 YP_002123702.1 CDS Sez_1353 NC_011134.1 1393284 1394210 R similar to ref|ZP_00365936.1| COG0826: Collagenase and related proteases [Streptococcus pyogenes M49 591]; peptidase U32 complement(1393284..1394210) Streptococcus equi subsp. zooepidemicus MGCS10565 6762000 YP_002123703.1 CDS Sez_1354 NC_011134.1 1394312 1394647 D similar to ref|ZP_00365937.1| COG0477: Permeases of the major facilitator superfamily [Streptococcus pyogenes M49 591]; hypothetical protein 1394312..1394647 Streptococcus equi subsp. zooepidemicus MGCS10565 6761980 YP_002123704.1 CDS Sez_1355 NC_011134.1 1394779 1395198 R similar to gb|ABF37458.1| hypothetical exported protein [Streptococcus pyogenes MGAS10750]; hypothetical protein complement(1394779..1395198) Streptococcus equi subsp. zooepidemicus MGCS10565 6761976 YP_002123705.1 CDS Sez_1356 NC_011134.1 1395195 1395599 R similar to ref|ZP_00365939.1| COG4768: Uncharacterized protein containing a divergent version of the methyl-accepting chemotaxis-like domain [Streptococcus pyogenes M49 591]; general stress protein complement(1395195..1395599) Streptococcus equi subsp. zooepidemicus MGCS10565 6761991 YP_002123706.1 CDS lgt NC_011134.1 1395621 1396400 R transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein; prolipoprotein diacylglyceryl transferase complement(1395621..1396400) Streptococcus equi subsp. zooepidemicus MGCS10565 6761983 YP_002123707.1 CDS hprK NC_011134.1 1396397 1397329 R catalyzes the phosphorylation of the phosphocarrier protein HPr of the bacterial phosphotransferase system; HPr kinase/phosphorylase complement(1396397..1397329) Streptococcus equi subsp. zooepidemicus MGCS10565 6761981 YP_002123708.1 CDS Sez_1359 NC_011134.1 1397607 1397879 R stress-responsive transcriptional regulator; similar to ref|YP_059824.1| stress-responsive transcriptional regulator [Streptococcus pyogenes MGAS10394]; phage shock protein C complement(1397607..1397879) Streptococcus equi subsp. zooepidemicus MGCS10565 6761975 YP_002123709.1 CDS Sez_1360 NC_011134.1 1397943 1398380 R similar to gb|ABF31661.1| metallopeptidase, SprT family [Streptococcus pyogenes MGAS9429]; hypothetical protein complement(1397943..1398380) Streptococcus equi subsp. zooepidemicus MGCS10565 6761958 YP_002123710.1 CDS Sez_1361 NC_011134.1 1398367 1400499 R similar to ref|YP_601996.1| transcription accessory protein [Streptococcus pyogenes MGAS10750]; S1 RNA-binding domain transcription accessory protein complement(1398367..1400499) Streptococcus equi subsp. zooepidemicus MGCS10565 6761969 YP_002123711.1 CDS Sez_1362 NC_011134.1 1400914 1402635 D similar to ref|ZP_01371554.1| transposase, IS4 [Desulfitobacterium hafniense DCB-2]; transposase IS4-like 1400914..1402635 Streptococcus equi subsp. zooepidemicus MGCS10565 6761948 YP_002123712.1 CDS Sez_1363 NC_011134.1 1402791 1403117 R similar to ref|YP_601318.1| hypothetical protein MGAS2096_Spy1722 [Streptococcus pyogenes MGAS2096]; hypothetical protein complement(1402791..1403117) Streptococcus equi subsp. zooepidemicus MGCS10565 6761962 YP_002123713.1 CDS pstB NC_011134.1 1403390 1404142 R ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation; phosphate transporter ATP-binding protein complement(1403390..1404142) Streptococcus equi subsp. zooepidemicus MGCS10565 6761954 YP_002123714.1 CDS pstA NC_011134.1 1404144 1404959 R similar to ref|ZP_01825632.1| phosphate ABC transporter, permease [Streptococcus pneumoniae SP11-BS70]; Part of the binding-protein-dependent transport system. Probably responsible for the translocation of the substrate across the membrane.; phosphate ABC transporter permease complement(1404144..1404959) Streptococcus equi subsp. zooepidemicus MGCS10565 6761935 YP_002123715.1 CDS pstC NC_011134.1 1404952 1405815 R similar to ref|NP_346505.1| phosphate ABC transporter, permease [Streptococcus pneumoniae TIGR4]; Part of the binding-protein-dependent transport system. Probably responsible for the translocation of the substrate across the membrane.; phosphate ABC transporter permease complement(1404952..1405815) Streptococcus equi subsp. zooepidemicus MGCS10565 6761934 YP_002123716.1 CDS pstS NC_011134.1 1405885 1406757 R similar to ref|NP_359486.1| ABC transporter substrate-binding protein - phosphate transport [Streptococcus pneumoniae R6]; Part of a binding-protein-dependent transport system.; phosphate ABC transporter substrate-binding protein complement(1405885..1406757) Streptococcus equi subsp. zooepidemicus MGCS10565 6761928 YP_002123717.1 CDS phoR NC_011134.1 1406916 1408214 R similar to ref|ZP_01817667.1| sensor histidine kinase PnpS [Streptococcus pneumoniae SP3-BS71]; Member of the two-component regulatory system phoP/phoR involved in the alkaline phosphatases genes regulation. PhoR may function as a membrane-associated protein kinase that phosphorylates phoP in response to environmental signals.; alkaline phosphatase synthesis sensor protein PhoR complement(1406916..1408214) Streptococcus equi subsp. zooepidemicus MGCS10565 6761925 YP_002123718.1 CDS phoP NC_011134.1 1408225 1408968 R similar to ref|ZP_01817666.1| response regulator [Streptococcus pneumoniae SP3-BS71]; Member of the two-component regulatory system phoP/phoR involved in the regulation of alkaline phosphatase genes phoA and phoB and of phosphodiesterase.; alkaline phosphatase synthesis transcriptional regulatory protein PhoP complement(1408225..1408968) Streptococcus equi subsp. zooepidemicus MGCS10565 6761919 YP_002123719.1 CDS Sez_1370 NC_011134.1 1409119 1409274 D similar to ref|NP_268841.1| hypothetical protein SPy_0577 [Streptococcus pyogenes M1 GAS]; hypothetical protein 1409119..1409274 Streptococcus equi subsp. zooepidemicus MGCS10565 6761930 YP_002123720.1 CDS Sez_1371 NC_011134.1 1409315 1410217 D similar to ref|YP_279928.1| hypothetical membrane spanning protein [Streptococcus pyogenes MGAS6180]; hypothetical protein 1409315..1410217 Streptococcus equi subsp. zooepidemicus MGCS10565 6761926 YP_002123721.1 CDS Sez_1372 NC_011134.1 1410217 1410474 D similar to ref|YP_279927.1| hypothetical membrane spanning protein [Streptococcus pyogenes MGAS6180]; hypothetical protein 1410217..1410474 Streptococcus equi subsp. zooepidemicus MGCS10565 6761899 YP_002123722.1 CDS Sez_1373 NC_011134.1 1410468 1411034 D similar to ref|YP_059819.1| Hypothetical membrane spanning protein [Streptococcus pyogenes MGAS10394]; hypothetical protein 1410468..1411034 Streptococcus equi subsp. zooepidemicus MGCS10565 6761916 YP_002123723.1 CDS Sez_1374 NC_011134.1 1411219 1412640 R similar to ref|YP_281839.1| 6-phospho-beta-glucosidase [Streptococcus pyogenes MGAS5005]; Can Hydrolyze Salicin And Arbutin.; 6-phospho-beta-glucosidase complement(1411219..1412640) Streptococcus equi subsp. zooepidemicus MGCS10565 6761914 YP_002123724.1 CDS Sez_1375 NC_011134.1 1412667 1413722 R similar to ref|YP_001128925.1| beta-glucoside-specific phosphotransferase system (PTS), IIABC component [Streptococcus pyogenes str. Manfredo]; The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. This system is involved in arbutin, cellobiose, and salicin transport.; PTS system arbutin-, cellobiose-, and salicin-specific transporter subunit IIBC complement(1412667..1413722) Streptococcus equi subsp. zooepidemicus MGCS10565 6761902 YP_002123725.1 CDS Sez_1376 NC_011134.1 1413704 1414528 R similar to ref|ZP_00365852.1| COG1263: Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Streptococcus pyogenes M49 591]; The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. This system is involved in beta-glucoside transport.; PTS system beta-glucoside-specific transporter subunit IIBCA complement(1413704..1414528) Streptococcus equi subsp. zooepidemicus MGCS10565 6761877 YP_002123726.1 CDS Sez_1377 NC_011134.1 1414533 1415372 R similar to ref|YP_281837.1| transcription antiterminator, BglG family [Streptococcus pyogenes MGAS5005]; Mediates positive regulation by functioning as an antiterminator factor of transcription.; transcription antiterminator complement(1414533..1415372) Streptococcus equi subsp. zooepidemicus MGCS10565 6761897 YP_002123727.1 CDS ftsY NC_011134.1 1415661 1417118 R similar to ref|YP_601988.1| Cell division protein ftsY [Streptococcus pyogenes MGAS10750]; Required for normal cell growth and morphogenesis; translocation of at least 1 protein is impaired in its absence.; signal recognition particle receptor protein FtsY subunit alpha complement(1415661..1417118) Streptococcus equi subsp. zooepidemicus MGCS10565 6761872 YP_002123728.1 CDS Sez_1379 NC_011134.1 1417118 1417945 R similar to ref|YP_059813.1| Hydrolase (HAD superfamily) [Streptococcus pyogenes MGAS10394]; hydrolase HAD superfamily complement(1417118..1417945) Streptococcus equi subsp. zooepidemicus MGCS10565 6761888 YP_002123729.1 CDS Sez_1380 NC_011134.1 1417946 1418743 R similar to ref|YP_001128930.1| haloacid dehalogenase-like hydrolase [Streptococcus pyogenes str. Manfredo]; hydrolase HAD superfamily complement(1417946..1418743) Streptococcus equi subsp. zooepidemicus MGCS10565 6761860 YP_002123730.1 CDS Sez_1381 NC_011134.1 1418946 1419134 R hypothetical protein complement(1418946..1419134) Streptococcus equi subsp. zooepidemicus MGCS10565 6761879 YP_002123731.1 CDS Sez_1382 NC_011134.1 1419261 1419710 R similar to ref|YP_001036160.1| hypothetical protein SSA_2248 [Streptococcus sanguinis SK36]; hypothetical protein complement(1419261..1419710) Streptococcus equi subsp. zooepidemicus MGCS10565 6761874 YP_002123732.1 CDS Sez_1383 NC_011134.1 1419767 1420390 R similar to ref|YP_599261.1| ABC transporter ATP-binding protein [Streptococcus pyogenes MGAS10270]; ABC transporter ATP-binding protein complement(1419767..1420390) Streptococcus equi subsp. zooepidemicus MGCS10565 6761852 YP_002123733.1 CDS Sez_1384 NC_011134.1 1420453 1422372 R similar to ref|YP_001036162.1| ABC-type antimicrobial peptide transporter, permease component, [Streptococcus sanguinis SK36]; ABC transporter permease complement(1420453..1422372) Streptococcus equi subsp. zooepidemicus MGCS10565 6761869 YP_002123734.1 CDS Sez_1385 NC_011134.1 1422439 1422744 R similar to gb|ABF34719.1| hypothetical exported protein [Streptococcus pyogenes MGAS10270]; hypothetical protein complement(1422439..1422744) Streptococcus equi subsp. zooepidemicus MGCS10565 6761863 YP_002123735.1 CDS Sez_1386 NC_011134.1 1422911 1423204 R hypothetical protein complement(1422911..1423204) Streptococcus equi subsp. zooepidemicus MGCS10565 6761855 YP_002123736.1 CDS Sez_1387 NC_011134.1 1423210 1424469 R similar to ref|ZP_00874485.1| Lipase, class 3 [Streptococcus suis 89/1591]; hypothetical protein complement(1423210..1424469) Streptococcus equi subsp. zooepidemicus MGCS10565 6761853 YP_002123737.1 CDS Sez_1388 NC_011134.1 1424501 1425016 R similar to ref|ZP_00780318.1| conserved hypothetical protein [Streptococcus agalactiae 18RS21]; hypothetical protein complement(1424501..1425016) Streptococcus equi subsp. zooepidemicus MGCS10565 6761850 YP_002123738.1 CDS Sez_1389 NC_011134.1 1425067 1425510 R similar to ref|ZP_00780318.1| conserved hypothetical protein [Streptococcus agalactiae 18RS21]; hypothetical protein complement(1425067..1425510) Streptococcus equi subsp. zooepidemicus MGCS10565 6761849 YP_002123739.1 CDS smc NC_011134.1 1425877 1429428 R similar to ref|ZP_00366640.1| COG1196: Chromosome segregation ATPases [Streptococcus pyogenes M49 591]; Plays an important role in chromosome structure and partitioning. Essential for chromosome partition.; chromosome partition protein Smc complement(1425877..1429428) Streptococcus equi subsp. zooepidemicus MGCS10565 6761846 YP_002123740.1 CDS rnc NC_011134.1 1429429 1430124 R cytoplasmic enzyme involved in processing rRNA and some mRNAs; substrates typically have dsRNA regions; forms a homodimer; have N-terminal nuclease and C-terminal RNA-binding domains; requires magnesium as preferred ion for activity; ribonuclease III complement(1429429..1430124) Streptococcus equi subsp. zooepidemicus MGCS10565 6761843 YP_002123741.1 CDS Sez_1392 NC_011134.1 1430380 1431195 R similar to ref|YP_597797.1| Transcriptional regulator [Streptococcus pyogenes MGAS10270]; transcriptional regulator RofA-like protein (RALP) complement(1430380..1431195) Streptococcus equi subsp. zooepidemicus MGCS10565 6761814 YP_002123742.1 CDS Sez_1393 NC_011134.1 1431196 1431894 R similar to ref|YP_001127764.1| regulatory protein-RofA related [Streptococcus pyogenes str. Manfredo]; transcriptional regulator RofA-like protein (RALP) complement(1431196..1431894) Streptococcus equi subsp. zooepidemicus MGCS10565 6761832 YP_002123743.1 CDS Sez_1394 NC_011134.1 1432774 1433583 R similar to ref|YP_059789.1| Zn-dependent hydrolase (beta-lactamase superfamily) [Streptococcus pyogenes MGAS10394]; Zn-dependent hydrolase (beta-lactamase superfamily) complement(1432774..1433583) Streptococcus equi subsp. zooepidemicus MGCS10565 6760964 YP_002123744.1 CDS vicK NC_011134.1 1433587 1434939 R similar to ref|YP_600051.1| Two-component sensor histidine kinase VicK [Streptococcus pyogenes MGAS2096]; TCS sensor kinase VicK complement(1433587..1434939) Streptococcus equi subsp. zooepidemicus MGCS10565 6760966 YP_002123745.1 CDS vicR NC_011134.1 1434932 1435642 R similar to emb|CAB65451.1| VicR protein [Streptococcus pyogenes]; TCS response regulator VicR complement(1434932..1435642) Streptococcus equi subsp. zooepidemicus MGCS10565 6760990 YP_002123746.1 CDS Sez_1397 NC_011134.1 1435839 1436858 R similar to ref|YP_596165.1| hypothetical cytosolic protein [Streptococcus pyogenes MGAS9429]; hypothetical protein complement(1435839..1436858) Streptococcus equi subsp. zooepidemicus MGCS10565 6760958 YP_002123747.1 CDS Sez_1398 NC_011134.1 1436904 1438166 R similar to ref|YP_600048.1| Long-chain-fatty-acid--CoA ligase [Streptococcus pyogenes MGAS2096]; Catalysis of the reaction: ATP + a long-chain carboxylic acid + CoA = AMP + diphosphate + an acyl-CoA; long-chain fatty acids have chain lengths of C12-18.; long-chain-fatty-acid--CoA ligase complement(1436904..1438166) Streptococcus equi subsp. zooepidemicus MGCS10565 6760984 YP_002123748.1 CDS Sez_1399 NC_011134.1 1438156 1439271 R similar to ref|ZP_00366633.1| COG0183: Acetyl-CoA acetyltransferase [Streptococcus pyogenes M49 591]; Thiolytic cleavage of beta-ketoadipyl-CoA to succinate and acetyl-CoA (by similarity).; acetyl-CoA C-acetyltransferase complement(1438156..1439271) Streptococcus equi subsp. zooepidemicus MGCS10565 6760978 YP_002123749.1 CDS Sez_1400 NC_011134.1 1439268 1439807 R similar to ref|NP_606782.1| hypothetical protein spyM18_0589 [Streptococcus pyogenes MGAS8232]; hypothetical protein complement(1439268..1439807) Streptococcus equi subsp. zooepidemicus MGCS10565 6760982 YP_002123750.1 CDS Sez_1401 NC_011134.1 1439916 1440065 R hypothetical protein complement(1439916..1440065) Streptococcus equi subsp. zooepidemicus MGCS10565 6760972 YP_002123751.1 CDS Sez_1402 NC_011134.1 1440281 1441042 R similar to ref|YP_279887.1| ABC transporter permease [Streptococcus pyogenes MGAS6180]; multidrug ABC transporter permease complement(1440281..1441042) Streptococcus equi subsp. zooepidemicus MGCS10565 6760979 YP_002123752.1 CDS Sez_1403 NC_011134.1 1441068 1441886 R similar to ref|YP_601937.1| Daunorubicin resistance transmembrane protein [Streptococcus pyogenes MGAS10750]; multidrug ABC transporter permease complement(1441068..1441886) Streptococcus equi subsp. zooepidemicus MGCS10565 6760968 YP_002123753.1 CDS Sez_1404 NC_011134.1 1441888 1442880 R similar to ref|ZP_00783216.1| ABC transporter, ATP-binding protein [Streptococcus agalactiae H36B]; ATP-binding transport protein complement(1441888..1442880) Streptococcus equi subsp. zooepidemicus MGCS10565 6760977 YP_002123754.1 CDS thrS NC_011134.1 1443162 1445129 R catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr); threonyl-tRNA synthetase complement(1443162..1445129) Streptococcus equi subsp. zooepidemicus MGCS10565 6760969 YP_002123755.1 CDS Sez_1406 NC_011134.1 1445683 1447017 R similar to ref|YP_279883.1| 1,2-diacylglycerol 3-glucosyltransferase [Streptococcus pyogenes MGAS6180]; 1,2-diacylglycerol 3-glucosyltransferase complement(1445683..1447017) Streptococcus equi subsp. zooepidemicus MGCS10565 6762331 YP_002123756.1 CDS Sez_1407 NC_011134.1 1447019 1448017 R similar to ref|YP_279882.1| glycosyltransferase [Streptococcus pyogenes MGAS6180]; glycosyltransferase complement(1447019..1448017) Streptococcus equi subsp. zooepidemicus MGCS10565 6762333 YP_002123757.1 CDS Sez_1408 NC_011134.1 1448087 1448212 R hypothetical protein complement(1448087..1448212) Streptococcus equi subsp. zooepidemicus MGCS10565 6762310 YP_002123758.1 CDS amyS NC_011134.1 1448314 1449771 R converts 1,4-alpha-D-glucans to maltodextrin; alpha-amylase complement(1448314..1449771) Streptococcus equi subsp. zooepidemicus MGCS10565 6762311 YP_002123759.1 CDS ccpA NC_011134.1 1449859 1450860 R similar to gb|ABL07487.1| catabolite control protein A [Streptococcus equi subsp. zooepidemicus]; Transcriptional regulator involved in both the repression of carbohydrate utilization genes and in the positive regulation of genes involved in excretion of excess carbon.; catabolite control protein A CCpA complement(1449859..1450860) Streptococcus equi subsp. zooepidemicus MGCS10565 6762330 YP_002123760.1 CDS Sez_1413 NC_011134.1 1452182 1452340 D hypothetical protein 1452182..1452340 Streptococcus equi subsp. zooepidemicus MGCS10565 6762339 YP_002123761.1 CDS Sez_1414 NC_011134.1 1452488 1453156 D similar to ref|NP_268790.1| NAD(P)H-flavin oxidoreductase [Streptococcus pyogenes M1 GAS]; oxygen-insensitive NAD(P)H nitroreductase / dihydropteridine reductase 1452488..1453156 Streptococcus equi subsp. zooepidemicus MGCS10565 6762340 YP_002123762.1 CDS Sez_1415 NC_011134.1 1453264 1454196 D similar to ref|YP_598030.1| Bactoprenol glucosyl transferase [Streptococcus pyogenes MGAS10270]; Catalyzes the transfer of the glucose residue from UDP-glucose to a lipid carrier (by similarity).; bactoprenol glucosyl transferase 1453264..1454196 Streptococcus equi subsp. zooepidemicus MGCS10565 6762338 YP_002123763.1 CDS Sez_1416 NC_011134.1 1454180 1454305 R hypothetical protein complement(1454180..1454305) Streptococcus equi subsp. zooepidemicus MGCS10565 6762336 YP_002123764.1 CDS smpB NC_011134.1 1454483 1454950 R binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation; SsrA-binding protein complement(1454483..1454950) Streptococcus equi subsp. zooepidemicus MGCS10565 6762318 YP_002123765.1 CDS rnr NC_011134.1 1454953 1457277 R similar to ref|YP_601921.1| Exoribonuclease II [Streptococcus pyogenes MGAS10750]; 3'-5'exoribonuclease that participates in an essential cell function. Acts nonspecifically on poly(A), poly(U) and ribosomal RNAs.; ribonuclease R Rnr complement(1454953..1457277) Streptococcus equi subsp. zooepidemicus MGCS10565 6762335 YP_002123766.1 CDS secG NC_011134.1 1457364 1457600 R similar to ref|NP_606756.1| preprotein translocase subunit SecG [Streptococcus pyogenes MGAS8232]; preprotein translocase subunit SecG complement(1457364..1457600) Streptococcus equi subsp. zooepidemicus MGCS10565 6760976 YP_002123767.1 CDS Sez_1420 NC_011134.1 1457808 1457936 R hypothetical protein complement(1457808..1457936) Streptococcus equi subsp. zooepidemicus MGCS10565 6762324 YP_002123768.1 CDS sclZ.9 NC_011134.1 1458393 1459889 D similar to emb|CAA68254.1| fibronectin-binding protein [Streptococcus equi]; Possible fibronectin-binding adhesin, has a collagen-structural-motif domain composed of 41 Gly-Xaa-Yaa repeats.; hypothetical protein 1458393..1459889 Streptococcus equi subsp. zooepidemicus MGCS10565 6760965 YP_002123769.1 CDS coaE NC_011134.1 1460044 1460637 R similar to ref|YP_059753.1| dephospho-CoA kinase [Streptococcus pyogenes MGAS10394]; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.; dephospho-CoA kinase CoaE complement(1460044..1460637) Streptococcus equi subsp. zooepidemicus MGCS10565 6760992 YP_002123770.1 CDS mutM NC_011134.1 1460637 1461527 R Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases; formamidopyrimidine-DNA glycosylase complement(1460637..1461527) Streptococcus equi subsp. zooepidemicus MGCS10565 6760993 YP_002123771.1 CDS bga NC_011134.1 1461929 1463728 R similar to ref|ZP_00875460.1| Beta-galactosidase [Streptococcus suis 89/1591]; Preferentially hydrolyzes beta(1->3) galactosyl linkages over beta(1->4) linkages.; beta-galactosidase precursor Bga complement(1461929..1463728) Streptococcus equi subsp. zooepidemicus MGCS10565 6760981 YP_002123772.1 CDS nanA NC_011134.1 1463854 1468494 R similar to ref|ZP_01968534.1| hypothetical protein RUMTOR_02111 [Ruminococcus torques ATCC 27756]; Catalysis of the hydrolysis of alpha-(2->3)-, alpha-(2->6)-, alpha-(2->8)-glycosidic linkages of terminal sialic residues in oligosaccharides, glycoproteins, glycolipids, colominic acid and synthetic substrates.; sialidase NanA-like complement(1463854..1468494) Streptococcus equi subsp. zooepidemicus MGCS10565 6760987 YP_002123773.1 CDS celC NC_011134.1 1468669 1470027 R similar to ref|ZP_01817544.1| Phosphotransferase system (PTS) cellobiose-specific, IIC component, [Streptococcus pneumoniae SP3-BS71]; Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + sugar(out) = protein histidine + sugar phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport.; PTS system cellobiose-specific transporter subunit IIC CelC complement(1468669..1470027) Streptococcus equi subsp. zooepidemicus MGCS10565 6760975 YP_002123774.1 CDS celB NC_011134.1 1470078 1471394 R similar to ref|ZP_01825420.1| phosphotransferase system cellobiose-specific component IIC [Streptococcus pneumoniae SP11-BS70]; The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. This system is involved in cellobiose transport.; cellobiose permease IIC component CelB complement(1470078..1471394) Streptococcus equi subsp. zooepidemicus MGCS10565 6760980 YP_002123775.1 CDS celA NC_011134.1 1471387 1471728 R similar to ref|ZP_00603570.1| Phosphotransferase system PTS, lactose/cellobiose-specific IIA subunit [Enterococcus faecium DO]; This is a component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system. The IIcd domains contain the sugar binding site and the transmembrane channel; the IIa domain contains the primary phosphorylation site (the donor is phospho-Hpr); IIa transfers its phosphoryl group to the IIb domain which finally transfers it to the sugar.; PTS system cellobiose-specific transporter subunit IIA CelA complement(1471387..1471728) Streptococcus equi subsp. zooepidemicus MGCS10565 6760974 YP_002123776.1 CDS Sez_1429 NC_011134.1 1471729 1472028 R similar to ref|YP_001034277.1| Phosphotransferase system (PTS) cellobiose-specific component IIB, [Streptococcus sanguinis SK36]; The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. This system is involved in cellobiose transport.; cellobiose-specific phosphotransferase enzyme IIB component complement(1471729..1472028) Streptococcus equi subsp. zooepidemicus MGCS10565 6760973 YP_002123777.1 CDS Sez_1430 NC_011134.1 1472070 1472969 R similar to ref|ZP_02186120.1| hypothetical protein CAT7_00288 [Carnobacterium sp. AT7]; Catalysis of the reaction: L-aspartate-4-semialdehyde + pyruvate = dihydrodipicolinate + 2 H2O.; dihydrodipicolinate synthase complement(1472070..1472969) Streptococcus equi subsp. zooepidemicus MGCS10565 6760991 YP_002123778.1 CDS xylR NC_011134.1 1473149 1474351 D similar to ref|YP_001034276.1| ROK family protein, [Streptococcus sanguinis SK36]; Transcriptional repressor of xylose-utilizing enzymes; xylose repressor XylR 1473149..1474351 Streptococcus equi subsp. zooepidemicus MGCS10565 6760967 YP_002123779.1 CDS Sez_1432 NC_011134.1 1474514 1475059 R similar to ref|YP_279846.1| phosphohydrolase [Streptococcus pyogenes MGAS6180]; MutT/nudix family protein complement(1474514..1475059) Streptococcus equi subsp. zooepidemicus MGCS10565 6760962 YP_002123780.1 CDS Sez_1433 NC_011134.1 1475301 1476632 R similar to ref|YP_001089191.1| permease [Clostridium difficile 630]; Permease For An Unknown Substrate.; D-beta-hydroxybutyrate permease complement(1475301..1476632) Streptococcus equi subsp. zooepidemicus MGCS10565 6760959 YP_002123781.1 CDS Sez_1434 NC_011134.1 1476723 1477496 R catalyzes the formation of acetoacetate from 3-hydroxybutyrate; 3-hydroxybutyrate dehydrogenase complement(1476723..1477496) Streptococcus equi subsp. zooepidemicus MGCS10565 6762352 YP_002123782.1 CDS Sez_1435 NC_011134.1 1477532 1478176 R similar to ref|YP_599072.1| Acetate CoA-transferase beta subunit [Streptococcus pyogenes MGAS10270]; Catalysis of the reaction: acyl-CoA + acetate = a fatty acid anion + acetyl-CoA.; butyrate--acetoacetate CoA-transferase subunit B complement(1477532..1478176) Streptococcus equi subsp. zooepidemicus MGCS10565 6762347 YP_002123783.1 CDS Sez_1436 NC_011134.1 1478182 1478814 R similar to ref|YP_602948.1| Acetate CoA-transferase alpha subunit [Streptococcus pyogenes MGAS10750]; Catalysis of the reaction: acyl-CoA + acetate = a fatty acid anion + acetyl-CoA.; acetate CoA-transferase subunit alpha complement(1478182..1478814) Streptococcus equi subsp. zooepidemicus MGCS10565 6760971 YP_002123784.1 CDS phaA NC_011134.1 1478847 1480037 R similar to ref|YP_597070.1| acetyl-CoA acetyltransferase [Streptococcus pyogenes MGAS9429]; Involved in the production of polyhydroxyalkonic acids (PHAs), composed primarily of 3-hydroxybutyric acid (3HB) and 3- hydroxyvaleric acid (3HV).; 3-ketoacyl-CoA thiolase complement(1478847..1480037) Streptococcus equi subsp. zooepidemicus MGCS10565 6760983 YP_002123785.1 CDS Sez_1438 NC_011134.1 1480229 1481131 D similar to ref|NP_269683.1| transcriptional regulator (LysR family) [Streptococcus pyogenes M1 GAS]; Positive Regulatory Protein; LysR family transcriptional regulator 1480229..1481131 Streptococcus equi subsp. zooepidemicus MGCS10565 6760960 YP_002123786.1 CDS Sez_1439 NC_011134.1 1482029 1482415 R similar to ref|ZP_00788202.1| membrane protein, [Streptococcus agalactiae CJB111]; hypothetical protein complement(1482029..1482415) Streptococcus equi subsp. zooepidemicus MGCS10565 6760961 YP_002123787.1 CDS Sez_1440 NC_011134.1 1482758 1482880 R hypothetical protein complement(1482758..1482880) Streptococcus equi subsp. zooepidemicus MGCS10565 6762351 YP_002123788.1 CDS era NC_011134.1 1483108 1484004 R Era; Escherichia coli Ras-like protein; Bex; Bacillus Era-complementing segment; essential protein in Escherichia coli that is involved in many cellular processes; GTPase; binds the cell membrane through apparent C-terminal domain; mutants are arrested during the cell cycle; Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome; GTP-binding protein Era complement(1483108..1484004) Streptococcus equi subsp. zooepidemicus MGCS10565 6762332 YP_002123789.1 CDS dgkA NC_011134.1 1484140 1484541 R similar to ref|NP_606734.1| diacylglycerol kinase [Streptococcus pyogenes MGAS8232]; Recycling of diacylglycerol produced during the turnover of membrane phospholipids. May play a role in adaptability to environmental stress conditions such as acid tolerance, elevated temperatures and high osmolarity.; diacylglycerol kinase DgkA complement(1484140..1484541) Streptococcus equi subsp. zooepidemicus MGCS10565 6762343 YP_002123790.1 CDS Sez_1443 NC_011134.1 1484522 1485019 R similar to gb|AAT86548.1| Hypothetical Metal-Binding Protein [Streptococcus pyogenes MGAS10394]; metalloprotease complement(1484522..1485019) Streptococcus equi subsp. zooepidemicus MGCS10565 6762321 YP_002123791.1 CDS Sez_1444 NC_011134.1 1485364 1485990 R similar to ref|YP_001035552.1| Acetyltransferase, GNAT family, [Streptococcus sanguinis SK36]; Catalysis of the transfer of an acetyl group to a nitrogen atom on the acceptor molecule.; ribosomal-protein-S5p-alanine acetyltransferase complement(1485364..1485990) Streptococcus equi subsp. zooepidemicus MGCS10565 6761854 YP_002123792.1 CDS Sez_1445 NC_011134.1 1486045 1486620 R similar to ref|YP_059730.1| Uracil DNA glycosylase superfamily protein [Streptococcus pyogenes MGAS10394]; uracil-DNA glycosylase complement(1486045..1486620) Streptococcus equi subsp. zooepidemicus MGCS10565 6761870 YP_002123793.1 CDS phoH NC_011134.1 1486664 1487767 R similar to ref|YP_596118.1| PhoH protein [Streptococcus pyogenes MGAS9429]; phosphate starvation-inducible protein PhoH complement(1486664..1487767) Streptococcus equi subsp. zooepidemicus MGCS10565 6762180 YP_002123794.1 CDS Sez_1447 NC_011134.1 1487870 1488085 R similar to ref|YP_138969.1| hypothetical protein stu0441 [Streptococcus thermophilus LMG 18311]; hypothetical protein complement(1487870..1488085) Streptococcus equi subsp. zooepidemicus MGCS10565 6761957 YP_002123795.1 CDS msrA NC_011134.1 1488082 1488591 R this stereospecific enzymes reduces the S isomer of methionine sulfoxide while MsrB reduces the R form; provides protection against oxidative stress; methionine sulfoxide reductase A complement(1488082..1488591) Streptococcus equi subsp. zooepidemicus MGCS10565 6762200 YP_002123796.1 CDS Sez_1449 NC_011134.1 1488929 1489786 R similar to ref|YP_819954.1| Predicted RNA-binding protein containing S1-like domain [Streptococcus thermophilus LMD-9]; S1 RNA binding domain complement(1488929..1489786) Streptococcus equi subsp. zooepidemicus MGCS10565 6761956 YP_002123797.1 CDS frr NC_011134.1 1489920 1490477 R Rrf; Frr; ribosome-recycling factor; release factor 4; RF4; recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G; A GTPase-dependent process results in release of 50S from 70S; inhibited by release factor RF-1; essential for viability; structurally similar to tRNAs; ribosome recycling factor complement(1489920..1490477) Streptococcus equi subsp. zooepidemicus MGCS10565 6762196 YP_002123798.1 CDS pyrH NC_011134.1 1490514 1491242 R Catalyzes the phosphorylation of UMP to UDP; uridylate kinase complement(1490514..1491242) Streptococcus equi subsp. zooepidemicus MGCS10565 6761971 YP_002123799.1 CDS Sez_1452 NC_011134.1 1491899 1492579 R similar to ref|YP_001034501.1| Peptide ABC transporter, ATP-binding protein, [Streptococcus sanguinis SK36]; Part of the ABC transporter complex. Responsible for energy coupling to the transport system.; nickel or oligopeptide import ATP-binding protein complement(1491899..1492579) Streptococcus equi subsp. zooepidemicus MGCS10565 6762189 YP_002123800.1 CDS Sez_1453 NC_011134.1 1492566 1493366 R similar to ref|YP_001034500.1| Peptide ABC transporter, ATP-binding protein, [Streptococcus sanguinis SK36]; Part of the ABC transporter complex . Responsible for energy coupling to the transport system.; nickel or oligopeptide transport ATP-binding protein complement(1492566..1493366) Streptococcus equi subsp. zooepidemicus MGCS10565 6761898 YP_002123801.1 CDS Sez_1454 NC_011134.1 1493342 1494148 R similar to ref|YP_001034500.1| Peptide ABC transporter, ATP-binding protein, [Streptococcus sanguinis SK36]; Membrane permease component of an ABC transporter complex.; nickel or oligopeptide transport system permease complement(1493342..1494148) Streptococcus equi subsp. zooepidemicus MGCS10565 6762170 YP_002123802.1 CDS Sez_1455 NC_011134.1 1494133 1495074 R similar to ref|ZP_00790162.1| peptide ABC transporter, permease [Streptococcus agalactiae 515]; Membrane permease component of an ABC transporter complex.; nickel or oligopeptide transport system permease complement(1494133..1495074) Streptococcus equi subsp. zooepidemicus MGCS10565 6761967 YP_002123803.1 CDS Sez_1456 NC_011134.1 1495152 1496774 R similar to ref|ZP_00788028.1| peptide ABC transporter, peptide-binding protein [Streptococcus agalactiae CJB111]; ABC transporter complex substrate-binding lipoprotein.; nickel or oligopeptide-binding periplasmic protein precursor complement(1495152..1496774) Streptococcus equi subsp. zooepidemicus MGCS10565 6762165 YP_002123804.1 CDS sclZ.10 NC_011134.1 1497283 1499283 D similar to gb|AAQ91575.1| collagen-like protein 3 [Streptococcus equi]; Possible fibronectin-binding adhesin, has a collagen-structural-motif domain composed of 97 Gly-Xaa-Yaa repeats.; hypothetical protein 1497283..1499283 Streptococcus equi subsp. zooepidemicus MGCS10565 6761966 YP_002123805.1 CDS rplA NC_011134.1 1499810 1500499 R in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA; 50S ribosomal protein L1 complement(1499810..1500499) Streptococcus equi subsp. zooepidemicus MGCS10565 6761947 YP_002123806.1 CDS rplK NC_011134.1 1500605 1501030 R binds directly to 23S ribosomal RNA; 50S ribosomal protein L11 complement(1500605..1501030) Streptococcus equi subsp. zooepidemicus MGCS10565 6762163 YP_002123807.1 CDS Sez_1461 NC_011134.1 1501204 1502157 R similar to ref|YP_138591.1| IS1239 transposase [Streptococcus thermophilus LMG 18311]; transposase IS1239 complement(1501204..1502157) Streptococcus equi subsp. zooepidemicus MGCS10565 6761946 YP_002123808.1 CDS Sez_1462 NC_011134.1 1502352 1503149 D similar to ref|YP_598726.1| Transcriptional regulator, LacI family [Streptococcus pyogenes MGAS10270]; LacI family transcriptional regulator 1502352..1503149 Streptococcus equi subsp. zooepidemicus MGCS10565 6762160 YP_002123809.1 CDS Sez_1463 NC_011134.1 1503313 1503663 D similar to ref|YP_281736.1| integral membrane protein [Streptococcus pyogenes MGAS5005]; hypothetical protein 1503313..1503663 Streptococcus equi subsp. zooepidemicus MGCS10565 6761944 YP_002123810.1 CDS ftsK NC_011134.1 1503869 1506268 R similar to ref|YP_001129017.1| DNA translocase FtsK [Streptococcus pyogenes str. Manfredo]; DNA motor protein, which is both required to move DNA out of the region of the septum during cell division and for the septum formation. Tracks DNA in an ATP-dependent manner by generating positive supercoils in front of it and negative supercoils behind it.; DNA translocase FtsK complement(1503869..1506268) Streptococcus equi subsp. zooepidemicus MGCS10565 6762140 YP_002123811.1 CDS Sez_1465 NC_011134.1 1506388 1506561 D hypothetical protein 1506388..1506561 Streptococcus equi subsp. zooepidemicus MGCS10565 6761943 YP_002123812.1 CDS Sez_1466 NC_011134.1 1506648 1507454 D similar to ref|NP_606719.1| cyclophilin-type protein [Streptococcus pyogenes MGAS8232]; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.; peptidyl-prolyl cis-trans isomerase cyclophilin-type 1506648..1507454 Streptococcus equi subsp. zooepidemicus MGCS10565 6762130 YP_002123813.1 CDS mtsC NC_011134.1 1507610 1508443 R similar to ref|NP_606718.1| integral membrane protein MtsC [Streptococcus pyogenes MGAS8232]; Part of an ATP-driven transport system for a metal; this complex ly has affinity for Zn(2+), Fe(3+) and Cu(2+).; metal ABC transporter permease MtsC-like complement(1507610..1508443) Streptococcus equi subsp. zooepidemicus MGCS10565 6761955 YP_002123814.1 CDS mtsB NC_011134.1 1508444 1509169 R similar to ref|YP_279827.1| manganese transport system ATP-binding protein [Streptococcus pyogenes MGAS6180]; Part of an ATP-driven transport system for a metal; this complex ly has affinity for Zn(2+), Fe(3+) and Cu(2+).; metal ABC transporter ATP-binding protein MtsB-like complement(1508444..1509169) Streptococcus equi subsp. zooepidemicus MGCS10565 6762148 YP_002123815.1 CDS mtsA NC_011134.1 1509229 1510161 R similar to ref|YP_001129021.1| metal ABC transporter substrate-binding lipoprotein precursor [Streptococcus pyogenes str. Manfredo]; Part of an ATP-driven transport system for a metal; this protein ly has affinity for Zn(2+), Fe(3+) and Cu(2+).; metal ABC transporter substrate-binding lipoprotein precursor MtsA-like complement(1509229..1510161) Streptococcus equi subsp. zooepidemicus MGCS10565 6761953 YP_002123816.1 CDS mtsR NC_011134.1 1510307 1510954 D similar to ref|YP_279825.1| iron-dependent repressor [Streptococcus pyogenes MGAS6180]; Iron-binding repressor of siderophore biosynthesis and iron uptake.; transcriptional regulator of metal ABC transporter MtsR-like 1510307..1510954 Streptococcus equi subsp. zooepidemicus MGCS10565 6762125 YP_002123817.1 CDS mtnN NC_011134.1 1511004 1511705 R enables the cleavage of the glycosidic bond in both 5'-methylthioadenosine and S-adenosylhomocysteine; 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase complement(1511004..1511705) Streptococcus equi subsp. zooepidemicus MGCS10565 6761952 YP_002123818.1 CDS Sez_1472 NC_011134.1 1511727 1511975 R similar to ref|YP_059706.1| Hypothetical membrane associated protein [Streptococcus pyogenes MGAS10394]; hypothetical protein complement(1511727..1511975) Streptococcus equi subsp. zooepidemicus MGCS10565 6762138 YP_002123819.1 CDS Sez_1473 NC_011134.1 1511975 1512529 R similar to ref|ZP_00365482.1| COG0494: NTP pyrophosphohydrolases including oxidative damage repair enzymes [Streptococcus pyogenes M49 591]; Acts on ADP-mannose and ADP-glucose as well as ADP- ribose. Prevents glycogen biosynthesis. The reaction catalyzed by this enzyme is a limiting step of the gluconeogenic process.; ADP-ribose pyrophosphatase complement(1511975..1512529) Streptococcus equi subsp. zooepidemicus MGCS10565 6761842 YP_002123820.1 CDS gcaD NC_011134.1 1512560 1513942 R similar to gb|AAQ05206.1|AF468690_1 UDP-N-acetyl-glucosamine pyrophosphorylase [Streptococcus equi subsp. zooepidemicus]; Bifunctional Enzyme Responsible For The Acetylation Of Glc-N-1-P To Give Glcnac-1-P And The Synthesis Of UDP-GlcNAc.; bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase complement(1512560..1513942) Streptococcus equi subsp. zooepidemicus MGCS10565 6762136 YP_002123821.1 CDS Sez_1475 NC_011134.1 1514151 1514279 D hypothetical protein 1514151..1514279 Streptococcus equi subsp. zooepidemicus MGCS10565 6761950 YP_002123822.1 CDS Sez_1476 NC_011134.1 1514286 1515260 R similar to ref|YP_601856.1| NAD-dependent oxidoreductase [Streptococcus pyogenes MGAS10750]; NAD-dependent oxidoreductase complement(1514286..1515260) Streptococcus equi subsp. zooepidemicus MGCS10565 6762112 YP_002123823.1 CDS Sez_1477 NC_011134.1 1515261 1515719 R similar to ref|ZP_00783841.1| conserved hypothetical protein [Streptococcus agalactiae H36B]; hypothetical protein complement(1515261..1515719) Streptococcus equi subsp. zooepidemicus MGCS10565 6761937 YP_002123824.1 CDS fabG NC_011134.1 1515918 1516616 R Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis; 3-ketoacyl-ACP reductase complement(1515918..1516616) Streptococcus equi subsp. zooepidemicus MGCS10565 6762104 YP_002123825.1 CDS Sez_1479 NC_011134.1 1516609 1516845 R similar to ref|YP_001450753.1| hypothetical protein SGO_1474 [Streptococcus gordonii str. Challis substr. CH1]; hypothetical protein complement(1516609..1516845) Streptococcus equi subsp. zooepidemicus MGCS10565 6761949 YP_002123826.1 CDS Sez_1480 NC_011134.1 1517351 1518067 D similar to ref|YP_597968.1| hypothetical protein MGAS10270_Spy0359 [Streptococcus pyogenes MGAS10270]; hypothetical protein 1517351..1518067 Streptococcus equi subsp. zooepidemicus MGCS10565 6762124 YP_002123827.1 CDS Sez_1481 NC_011134.1 1518260 1518862 R similar to ref|ZP_00780519.1| cell surface protein, ErfK family [Streptococcus agalactiae 18RS21]; cell surface protein ErfK family complement(1518260..1518862) Streptococcus equi subsp. zooepidemicus MGCS10565 6761915 YP_002123828.1 CDS valS NC_011134.1 1518954 1521605 R valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain; valyl-tRNA synthetase complement(1518954..1521605) Streptococcus equi subsp. zooepidemicus MGCS10565 6762121 YP_002123829.1 CDS Sez_1483 NC_011134.1 1521618 1522181 R similar to ref|YP_597018.1| hypothetical protein MGAS9429_Spy1287 [Streptococcus pyogenes MGAS9429]; hypothetical protein complement(1521618..1522181) Streptococcus equi subsp. zooepidemicus MGCS10565 6761932 YP_002123830.1 CDS Sez_1484 NC_011134.1 1522381 1522965 R similar to ref|ZP_00788728.1| acetyltransferase, GNAT family [Streptococcus agalactiae CJB111]; GNAT family acetyltransferase complement(1522381..1522965) Streptococcus equi subsp. zooepidemicus MGCS10565 6762118 YP_002123831.1 CDS Sez_1485 NC_011134.1 1522962 1523165 R hypothetical protein complement(1522962..1523165) Streptococcus equi subsp. zooepidemicus MGCS10565 6761945 YP_002123832.1 CDS Sez_1486 NC_011134.1 1523227 1523727 R similar to ref|YP_280764.1| hypothetical cytosolic protein [Streptococcus pyogenes MGAS6180]; hypothetical protein complement(1523227..1523727) Streptococcus equi subsp. zooepidemicus MGCS10565 6762115 YP_002123833.1 CDS Sez_1487 NC_011134.1 1523749 1524003 R similar to ref|NP_665082.1| hypothetical protein SpyM3_1278 [Streptococcus pyogenes MGAS315]; hypothetical protein complement(1523749..1524003) Streptococcus equi subsp. zooepidemicus MGCS10565 6761911 YP_002123834.1 CDS Sez_1488 NC_011134.1 1524721 1525071 D hypothetical protein 1524721..1525071 Streptococcus equi subsp. zooepidemicus MGCS10565 6761139 YP_002123835.1 CDS aroA NC_011134.1 1525320 1526075 D catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate; 3-deoxy-7-phosphoheptulonate synthase 1525320..1526075 Streptococcus equi subsp. zooepidemicus MGCS10565 6761927 YP_002123836.1 CDS aroB NC_011134.1 1526110 1527216 D catalyzes the formation of 3-dehydroquinate from 3-deoxy-arabino-heptulonate 7-phosphate; functions in aromatic amino acid biosynthesis; 3-dehydroquinate synthase 1526110..1527216 Streptococcus equi subsp. zooepidemicus MGCS10565 6762084 YP_002123837.1 CDS Sez_1491 NC_011134.1 1527366 1528052 D similar to ref|YP_139291.1| ISSth1, transposase (orf1), IS3 family [Streptococcus thermophilus LMG 18311]; ISSth1, transposase orfA, IS3 family 1527366..1528052 Streptococcus equi subsp. zooepidemicus MGCS10565 6761940 YP_002123838.1 CDS Sez_1492 NC_011134.1 1528139 1528510 D similar to ref|YP_139290.1| ISSth1, transposase (orf2), IS3 family [Streptococcus thermophilus LMG 18311]; ISSth1, transposase orfB, IS3 family 1528139..1528510 Streptococcus equi subsp. zooepidemicus MGCS10565 6762077 YP_002123839.1 CDS Sez_1493 NC_011134.1 1528494 1528937 D similar to ref|YP_140248.1| ISSth1, transposase (orf2), IS3 family [Streptococcus thermophilus LMG 18311]; ISSth1, transposase orfC, IS3 family 1528494..1528937 Streptococcus equi subsp. zooepidemicus MGCS10565 6761941 YP_002123840.1 CDS Sez_1494 NC_011134.1 1529234 1530007 R similar to ref|YP_329133.1| hypothetical protein SAK_0495 [Streptococcus agalactiae A909]; Catalysis of the reaction: uridine + phosphate = uracil + alpha-D-ribose 1-phosphate.; phosphorylase Pnp/Udp family complement(1529234..1530007) Streptococcus equi subsp. zooepidemicus MGCS10565 6762093 YP_002123841.1 CDS aroE NC_011134.1 1530133 1531017 R similar to ref|YP_280809.1| shikimate 5-dehydrogenase [Streptococcus pyogenes MGAS6180]; Aromatic amino acids biosynthesis; shikimate pathway; fourth step.; shikimate dehydrogenase complement(1530133..1531017) Streptococcus equi subsp. zooepidemicus MGCS10565 6761924 YP_002123842.1 CDS lacZ NC_011134.1 1531168 1534611 R similar to ref|ZP_00366242.1| COG3250: Beta-galactosidase/beta-glucuronidase [Streptococcus pyogenes M49 591]; Catalysis of the hydrolysis of terminal, non-reducing beta-D-galactose residues in beta-D-galactosides.; beta-galactosidase LacZ complement(1531168..1534611) Streptococcus equi subsp. zooepidemicus MGCS10565 6762091 YP_002123843.1 CDS yesN NC_011134.1 1534625 1536109 R similar to ref|YP_602908.1| Two-component response regulator yesN [Streptococcus pyogenes MGAS10750]; TCS response regulator YesN-like complement(1534625..1536109) Streptococcus equi subsp. zooepidemicus MGCS10565 6761938 YP_002123844.1 CDS yesM NC_011134.1 1536109 1537803 R similar to ref|YP_602909.1| Two-component sensor kinase yesM [Streptococcus pyogenes MGAS10750]; TCS sensor kinase YesM-like complement(1536109..1537803) Streptococcus equi subsp. zooepidemicus MGCS10565 6762066 YP_002123845.1 CDS Sez_1499 NC_011134.1 1537823 1538428 R similar to ref|YP_001128123.1| hypothetical protein SpyM50548 [Streptococcus pyogenes str. Manfredo]; hypothetical protein complement(1537823..1538428) Streptococcus equi subsp. zooepidemicus MGCS10565 6761933 YP_002123846.1 CDS Sez_1500 NC_011134.1 1538602 1538760 R hypothetical protein complement(1538602..1538760) Streptococcus equi subsp. zooepidemicus MGCS10565 6762063 YP_002123847.1 CDS Sez_1501 NC_011134.1 1538776 1540266 R similar to ref|NP_665093.1| sugar ABC transporter substrate binding protein [Streptococcus pyogenes MGAS315]; Probale ABC transporter substrate-binding lipoprotein.; hypothetical protein complement(1538776..1540266) Streptococcus equi subsp. zooepidemicus MGCS10565 6761923 YP_002123848.1 CDS msmG NC_011134.1 1540305 1541231 R similar to ref|NP_269653.1| sugar-binding transport protein [Streptococcus pyogenes M1 GAS]; Probably part of a binding-protein-dependent transport system. Probably responsible for the translocation of the substrate across the membrane.; multiple sugar ABC transporter permease MsmG complement(1540305..1541231) Streptococcus equi subsp. zooepidemicus MGCS10565 6762079 YP_002123849.1 CDS msmF NC_011134.1 1541241 1542191 R similar to ref|YP_060646.1| Sugar transport system permease [Streptococcus pyogenes MGAS10394]; Probably part of a binding-protein-dependent transport system. Probably responsible for the translocation of the substrate across the membrane.; multiple sugar ABC transporter permease MsmF complement(1541241..1542191) Streptococcus equi subsp. zooepidemicus MGCS10565 6761905 YP_002123850.1 CDS Sez_1504 NC_011134.1 1542403 1543296 D similar to ref|YP_282674.1| glucokinase [Streptococcus pyogenes MGAS5005]; Catalysis of the reaction: ATP + N-acyl-D-mannosamine = ADP + N-acyl-D-mannosamine 6-phosphate.; N-acetylmannosamine kinase 1542403..1543296 Streptococcus equi subsp. zooepidemicus MGCS10565 6762074 YP_002123851.1 CDS Sez_1505 NC_011134.1 1543284 1545284 D similar to ref|ZP_00602650.1| Alpha-1,2-mannosidase, [Enterococcus faecium DO]; alpha-1 2-mannosidase 1543284..1545284 Streptococcus equi subsp. zooepidemicus MGCS10565 6761904 YP_002123852.1 CDS bglA NC_011134.1 1545779 1547170 R similar to ref|YP_280819.1| beta-glucosidase [Streptococcus pyogenes MGAS6180]; Can hydrolyze salicin, cellobiose, and probably arbutin.; beta-glucosidase A BglA complement(1545779..1547170) Streptococcus equi subsp. zooepidemicus MGCS10565 6762058 YP_002123853.1 CDS hylZ NC_011134.1 1547197 1548891 R similar to ref|NP_665098.1| hyaluronidase [Streptococcus pyogenes MGAS315]; virulence factor which is likely to act on connective tissue during invasive infections, lacks a classical SrtA secretion signal sequence.; hyalurononglucosaminidase HylZ complement(1547197..1548891) Streptococcus equi subsp. zooepidemicus MGCS10565 6761922 YP_002123854.1 CDS Sez_1508 NC_011134.1 1548906 1549964 R similar to ref|YP_001128116.1| GntR family regulatory protein [Streptococcus pyogenes str. Manfredo]; Transcriptional repressor like that of the arabinose utilization genes.; AraC family transcriptional regulator complement(1548906..1549964) Streptococcus equi subsp. zooepidemicus MGCS10565 6762068 YP_002123855.1 CDS Sez_1509 NC_011134.1 1550098 1551384 D similar to ref|YP_060652.1| hypothetical protein M6_Spy1334 [Streptococcus pyogenes MGAS10394]; hypothetical protein 1550098..1551384 Streptococcus equi subsp. zooepidemicus MGCS10565 6761920 YP_002123856.1 CDS Sez_1510 NC_011134.1 1551456 1554125 D similar to ref|ZP_00365680.1| COG0383: Alpha-mannosidase [Streptococcus pyogenes M49 591]; Hydrolysis of terminal, non-reducing ?-D-mannose residues in ?-D-mannosides.; alpha-mannosidase 1551456..1554125 Streptococcus equi subsp. zooepidemicus MGCS10565 6762044 YP_002123857.1 CDS Sez_1511 NC_011134.1 1554309 1554917 R similar to ref|YP_001036161.1| ABC-type antimicrobial peptide transporter, ATPase component, [Streptococcus sanguinis SK36]; Part of the ABC transporter complex which could be involved in peptide resistance. Responsible for energy coupling to the transport system ().; ABC transporter ATP-binding protein complement(1554309..1554917) Streptococcus equi subsp. zooepidemicus MGCS10565 6761918 YP_002123858.1 CDS Sez_1512 NC_011134.1 1554914 1556917 R similar to ref|YP_001036162.1| ABC-type antimicrobial peptide transporter, permease component, [Streptococcus sanguinis SK36]; ABC transporter permease complement(1554914..1556917) Streptococcus equi subsp. zooepidemicus MGCS10565 6762041 YP_002123859.1 CDS Sez_1513 NC_011134.1 1557581 1557820 D hypothetical protein 1557581..1557820 Streptococcus equi subsp. zooepidemicus MGCS10565 6761893 YP_002123860.1 CDS pat NC_011134.1 1557912 1558589 R similar to ref|YP_535527.1| Phosphinothricin N-acetyltransferase [Lactobacillus salivarius UCC118]; This enzyme is an effector of phosphinothricin tripeptide (PTT or bialaphos) resistance. Inactivates PTT by transfer of an acetyl group.; Phosphinothricin N-acetyltransferase complement(1557912..1558589) Streptococcus equi subsp. zooepidemicus MGCS10565 6762039 YP_002123861.1 CDS Sez_1515 NC_011134.1 1558753 1559166 R similar to ref|NP_722218.1| immunity protein, BLpL-like [Streptococcus mutans UA159]; bacteriocin immunity protein BLpL-Like complement(1558753..1559166) Streptococcus equi subsp. zooepidemicus MGCS10565 6761913 YP_002123862.1 CDS Sez_1516 NC_011134.1 1559828 1560031 R similar to ref|ZP_01821308.1| BlpN protein [Streptococcus pneumoniae SP6-BS73]; bacteriocin BlpN-like complement(1559828..1560031) Streptococcus equi subsp. zooepidemicus MGCS10565 6762037 YP_002123863.1 CDS Sez_1517 NC_011134.1 1560048 1560302 R similar to ref|ZP_01821307.1| bacteriocin BlpM [Streptococcus pneumoniae SP6-BS73]; bacteriocin BlpM-like complement(1560048..1560302) Streptococcus equi subsp. zooepidemicus MGCS10565 6761889 YP_002123864.1 CDS Sez_1518 NC_011134.1 1560456 1560752 R similar to gb|ABQ23940.1| ubericin A immunity protein [Streptococcus uberis]; immunity protein complement(1560456..1560752) Streptococcus equi subsp. zooepidemicus MGCS10565 6762034 YP_002123865.1 CDS Sez_1519 NC_011134.1 1561281 1561796 D similar to ref|NP_688076.1| IS861, transposase OrfA [Streptococcus agalactiae 2603V/R]; transposase IS861 orfA 1561281..1561796 Streptococcus equi subsp. zooepidemicus MGCS10565 6761912 YP_002123866.1 CDS Sez_1520 NC_011134.1 1561793 1562629 D similar to ref|NP_720882.1| transposase, ISSmu1 [Streptococcus mutans UA159]; transposase IS861 orfB 1561793..1562629 Streptococcus equi subsp. zooepidemicus MGCS10565 6762031 YP_002123867.1 CDS Sez_1521 NC_011134.1 1563014 1563310 R similar to dbj|BAF37251.1| hypothetical protein [Streptococcus bovis]; hypothetical protein complement(1563014..1563310) Streptococcus equi subsp. zooepidemicus MGCS10565 6761910 YP_002123868.1 CDS Sez_1522 NC_011134.1 1563317 1563550 R similar to gb|AAG29818.1|AF298196_1 bovicin 255 peptide precursor [Streptococcus sp. LRC 0255]; bacteriocin-like peptide complement(1563317..1563550) Streptococcus equi subsp. zooepidemicus MGCS10565 6762047 YP_002123869.1 CDS Sez_1523 NC_011134.1 1563824 1565980 D similar to ref|YP_601902.1| Bacteriocin processing peptidase / Bacteriocin export ABC transporter [Streptococcus pyogenes MGAS10750]; Possibly involved in transport of competence-stimulating peptide (CSP).; transport/processing ATP-binding protein ComA-like 1563824..1565980 Streptococcus equi subsp. zooepidemicus MGCS10565 6761909 YP_002123870.1 CDS Sez_1524 NC_011134.1 1565949 1567349 D similar to ref|ZP_01821305.1| BlpC ABC transporter [Streptococcus pneumoniae SP6-BS73]; peptide ABC transporter 1565949..1567349 Streptococcus equi subsp. zooepidemicus MGCS10565 6762006 YP_002123871.1 CDS Sez_1525 NC_011134.1 1567449 1567583 D similar to emb|CAC10163.1| bacteriocin-like peptide, double glycin clevage motif [Streptococcus pneumoniae]; bacteriocin peptide BlpC-like 1567449..1567583 Streptococcus equi subsp. zooepidemicus MGCS10565 6761907 YP_002123872.1 CDS Sez_1526 NC_011134.1 1567702 1569036 R similar to ref|ZP_00788187.1| sensor histidine kinase BlpH, [Streptococcus agalactiae CJB111]; TCS sensor kinase complement(1567702..1569036) Streptococcus equi subsp. zooepidemicus MGCS10565 6762030 YP_002123873.1 CDS Sez_1527 NC_011134.1 1569036 1569785 R similar to ref|NP_688944.1| response regulator [Streptococcus agalactiae 2603V/R]; TCS response regulator FasA/ComE/BlpR-like complement(1569036..1569785) Streptococcus equi subsp. zooepidemicus MGCS10565 6761906 YP_002123874.1 CDS Sez_1528 NC_011134.1 1570082 1571035 R similar to ref|YP_138591.1| IS1239 transposase [Streptococcus thermophilus LMG 18311]; transposase IS1239 complement(1570082..1571035) Streptococcus equi subsp. zooepidemicus MGCS10565 6762016 YP_002123875.1 CDS Sez_1529 NC_011134.1 1571510 1571713 R similar to gb|AAB91456.1| enhancer peptide for thermophilin 13 precursor; ThmB [Streptococcus thermophilus]; TmhB-like bacteriocin enhancer peptide complement(1571510..1571713) Streptococcus equi subsp. zooepidemicus MGCS10565 6761903 YP_002123876.1 CDS Sez_1530 NC_011134.1 1571730 1571987 R similar to gb|AAB91455.1| amphipathic pore-forming peptide precursor; ThmA [Streptococcus thermophilus]; ThmA-like bacteriocin complement(1571730..1571987) Streptococcus equi subsp. zooepidemicus MGCS10565 6762009 YP_002123877.1 CDS Sez_1531 NC_011134.1 1572308 1573675 R similar to ref|YP_599044.1| tRNA (Uracil-5-) -methyltransferase [Streptococcus pyogenes MGAS10270]; Could Be A 23s rRNA (Uracil-5-)-Methyltransferase.; RNA methyltransferase TrmA family complement(1572308..1573675) Streptococcus equi subsp. zooepidemicus MGCS10565 6761901 YP_002123878.1 CDS Sez_1532 NC_011134.1 1573672 1574640 R similar to ref|ZP_00144239.1| hypothetical protein [Fusobacterium nucleatum subsp. vincentii ATCC 49256]; hypothetical protein complement(1573672..1574640) Streptococcus equi subsp. zooepidemicus MGCS10565 6762025 YP_002123879.1 CDS Sez_1533 NC_011134.1 1575390 1575905 D similar to ref|YP_602677.1| Transposase [Streptococcus pyogenes MGAS10750]; transposase IS861 orfA 1575390..1575905 Streptococcus equi subsp. zooepidemicus MGCS10565 6761873 YP_002123880.1 CDS Sez_1534 NC_011134.1 1575929 1576732 D similar to ref|NP_268574.1| transposase, IS861 [Streptococcus pyogenes M1 GAS]; transposase IS861 orfB 1575929..1576732 Streptococcus equi subsp. zooepidemicus MGCS10565 6762018 YP_002123881.1 CDS Sez_1535 NC_011134.1 1576902 1577162 D similar to ref|ZP_01963858.1| hypothetical protein RUMOBE_01582 [Ruminococcus obeum ATCC 29174]; hypothetical protein 1576902..1577162 Streptococcus equi subsp. zooepidemicus MGCS10565 6761890 YP_002123882.1 CDS Sez_1536 NC_011134.1 1577231 1579663 D similar to ref|ZP_00372061.1| adenine/cytosine DNA methyltransferase [Campylobacter upsaliensis RM3195]; adenine/cytosine DNA methyltransferase 1577231..1579663 Streptococcus equi subsp. zooepidemicus MGCS10565 6762014 YP_002123883.1 CDS Sez_1537 NC_011134.1 1579680 1580186 D similar to ref|ZP_02436627.1| hypothetical protein BACSTE_02895 [Bacteroides stercoris ATCC 43183]; hypothetical protein 1579680..1580186 Streptococcus equi subsp. zooepidemicus MGCS10565 6761891 YP_002123884.1 CDS Sez_1538 NC_011134.1 1580183 1581436 D similar to emb|CAI94870.1| Hin4II restriction endonuclease [Haemophilus influenzae]; hypothetical protein 1580183..1581436 Streptococcus equi subsp. zooepidemicus MGCS10565 6762008 YP_002123885.1 CDS Sez_1539 NC_011134.1 1581446 1582375 D similar to ref|YP_001035816.1| hypothetical protein SSA_1888 [Streptococcus sanguinis SK36]; hypothetical protein 1581446..1582375 Streptococcus equi subsp. zooepidemicus MGCS10565 6761809 YP_002123886.1 CDS Sez_1540 NC_011134.1 1582376 1584436 D similar to ref|ZP_02063370.1| hypothetical protein BACOVA_00315 [Bacteroides ovatus ATCC 8483]; hypothetical protein 1582376..1584436 Streptococcus equi subsp. zooepidemicus MGCS10565 6761990 YP_002123887.1 CDS recX NC_011134.1 1584673 1585449 D binds RecA and inhibits RecA-mediated DNA strand exchange and ATP hydrolysis and coprotease activities; recombination regulator RecX 1584673..1585449 Streptococcus equi subsp. zooepidemicus MGCS10565 6761865 YP_002123888.1 CDS Sez_1542 NC_011134.1 1585682 1586215 D similar to ref|ZP_00365988.1| COG3557: Uncharacterized domain/protein associated with RNAses G and E [Streptococcus pyogenes M49 591]; hypothetical protein 1585682..1586215 Streptococcus equi subsp. zooepidemicus MGCS10565 6761987 YP_002123889.1 CDS Sez_1543 NC_011134.1 1586465 1586776 D similar to ref|NP_722103.1| hypothetical protein SMU.1782 [Streptococcus mutans UA159]; hypothetical protein 1586465..1586776 Streptococcus equi subsp. zooepidemicus MGCS10565 6761887 YP_002123890.1 CDS Sez_1544 NC_011134.1 1587436 1587804 D similar to ref|ZP_00875692.1| Transposase, IS204/IS1001/IS1096/IS1165 [Streptococcus suis 89/1591]; transposase, ISL3 family 1587436..1587804 Streptococcus equi subsp. zooepidemicus MGCS10565 6761982 YP_002123891.1 CDS PSrp-1 NC_011134.1 1593817 1594365 R similar to ref|NP_665162.1| ribosomal subunit interface protein [Streptococcus pyogenes MGAS315]; Probably Modulates The Activity Of Sigma(54) (RpoN).; ribosomal subunit interface protein complement(1593817..1594365) Streptococcus equi subsp. zooepidemicus MGCS10565 6761173 YP_002123892.1 CDS comFC NC_011134.1 1594441 1595022 R similar to ref|YP_060690.1| ComF operon protein 3 [Streptococcus pyogenes MGAS10394]; Involved in transformation (competence for DNA uptake).; competence protein ComF complement(1594441..1595022) Streptococcus equi subsp. zooepidemicus MGCS10565 6761996 YP_002123893.1 CDS comFA NC_011134.1 1595081 1596403 R similar to ref|YP_599052.1| COMF operon protein 1 [Streptococcus pyogenes MGAS10270]; Involved in transformation (competence for DNA uptake). Required for DNA uptake but not for binding. May provide the driving force for transport of DNA through an aqueous channel.; competence protein ComF complement(1595081..1596403) Streptococcus equi subsp. zooepidemicus MGCS10565 6761883 YP_002123894.1 CDS Sez_1548 NC_011134.1 1596459 1597100 D similar to ref|NP_665166.1| hypothetical protein SpyM3_1362 [Streptococcus pyogenes MGAS315]; hypothetical protein 1596459..1597100 Streptococcus equi subsp. zooepidemicus MGCS10565 6761973 YP_002123895.1 CDS cysK NC_011134.1 1597222 1598148 D similar to ref|ZP_00875431.1| Cysteine synthase K/M:Cysteine synthase A [Streptococcus suis 89/1591]; Cysteine biosynthesis, Catalysis of the reaction: O3-acetyl-L-serine + H2S = L-cysteine + acetate.; cysteine synthase 1597222..1598148 Streptococcus equi subsp. zooepidemicus MGCS10565 6761861 YP_002123896.1 CDS Sez_1550 NC_011134.1 1598417 1598554 D hypothetical protein 1598417..1598554 Streptococcus equi subsp. zooepidemicus MGCS10565 6761986 YP_002123897.1 CDS Sez_1551 NC_011134.1 1598535 1598897 R similar to gb|AAN58235.1|AE014894_12 polyribonucleotide nucleotidyltransferase (general stress protein 13) [Streptococcus mutans UA159]; Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno purine-rich sequence.; hypothetical protein complement(1598535..1598897) Streptococcus equi subsp. zooepidemicus MGCS10565 6761881 YP_002123898.1 CDS Sez_1552 NC_011134.1 1598897 1600309 R similar to ref|YP_060695.1| Peptidyl-prolyl cis-trans isomerase [Streptococcus pyogenes MGAS10394]; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.; peptidyl-prolyl cis-trans isomerase-like complement(1598897..1600309) Streptococcus equi subsp. zooepidemicus MGCS10565 6761984 YP_002123899.1 CDS yvqC NC_011134.1 1600331 1600924 R similar to ref|YP_060696.1| Two-component response regulator yvqC [Streptococcus pyogenes MGAS10394]; TCS response regulator YvqC-like complement(1600331..1600924) Streptococcus equi subsp. zooepidemicus MGCS10565 6761880 YP_002123900.1 CDS yvqE NC_011134.1 1600965 1601969 R similar to ref|NP_607684.1| two-component sensor histidine kinase [Streptococcus pyogenes MGAS8232]; TCS sensor kinase YvqE-like complement(1600965..1601969) Streptococcus equi subsp. zooepidemicus MGCS10565 6761448 YP_002123901.1 CDS yvqF NC_011134.1 1601966 1602622 R similar to ref|YP_001128043.1| hypothetical protein SpyM50457 [Streptococcus pyogenes str. Manfredo]; hypothetical transporter protein YvqF-like complement(1601966..1602622) Streptococcus equi subsp. zooepidemicus MGCS10565 6761482 YP_002123902.1 CDS prkC NC_011134.1 1602791 1604686 R similar to ref|YP_599060.1| Serine/threonine protein kinase [Streptococcus pyogenes MGAS10270]; Regulation of stationary phase.; serine/threonine protein kinase PrkC complement(1602791..1604686) Streptococcus equi subsp. zooepidemicus MGCS10565 6761481 YP_002123903.1 CDS prpC NC_011134.1 1604683 1605423 R similar to ref|NP_269676.1| phosphoprotein phosphatase [Streptococcus pyogenes M1 GAS]; Regulation of stationary phase.; serine/threonine phosphatase PrpC complement(1604683..1605423) Streptococcus equi subsp. zooepidemicus MGCS10565 6761480 YP_002123904.1 CDS rsmB NC_011134.1 1605461 1606789 R similar to ref|YP_060701.1| 16S rRNA m(5)C 967 methyltransferase [Streptococcus pyogenes MGAS10394]; 16S rRNA m(5)C 967 methyltransferase RsmB complement(1605461..1606789) Streptococcus equi subsp. zooepidemicus MGCS10565 6761474 YP_002123905.1 CDS fmt NC_011134.1 1606773 1607690 R modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet) which is important in translation initiation; inactivation of this gene in Escherichia coli severely impairs growth; methionyl-tRNA formyltransferase complement(1606773..1607690) Streptococcus equi subsp. zooepidemicus MGCS10565 6761449 YP_002123906.1 CDS priA NC_011134.1 1607775 1610159 R binding of PriA to forked DNA starts the assembly of the primosome, also possesses 3'-5' helicase activity; primosome assembly protein PriA complement(1607775..1610159) Streptococcus equi subsp. zooepidemicus MGCS10565 6761355 YP_002123907.1 CDS rpoZ NC_011134.1 1610223 1610540 R Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits; DNA-directed RNA polymerase subunit omega complement(1610223..1610540) Streptococcus equi subsp. zooepidemicus MGCS10565 6761470 YP_002123908.1 CDS gmk NC_011134.1 1610565 1611191 R Essential for recycling GMP and indirectly, cGMP; guanylate kinase complement(1610565..1611191) Streptococcus equi subsp. zooepidemicus MGCS10565 6761468 YP_002123909.1 CDS Sez_1563 NC_011134.1 1611202 1611339 R hypothetical protein complement(1611202..1611339) Streptococcus equi subsp. zooepidemicus MGCS10565 6761467 YP_002123910.1 CDS Sez_1564 NC_011134.1 1611355 1612965 R similar to ref|NP_269682.1| hypothetical protein SPy_1633 [Streptococcus pyogenes M1 GAS]; hypothetical protein complement(1611355..1612965) Streptococcus equi subsp. zooepidemicus MGCS10565 6761444 YP_002123911.1 CDS luxS NC_011134.1 1613077 1613607 D catalyzes the hydrolysis of S-ribosylhomocysteine to homocysteine and autoinducer-2; S-ribosylhomocysteinase 1613077..1613607 Streptococcus equi subsp. zooepidemicus MGCS10565 6761465 YP_002123912.1 CDS Sez_1566 NC_011134.1 1613754 1615205 R similar to ref|NP_665189.1| hypothetical protein SpyM3_1385 [Streptococcus pyogenes MGAS315]; hypothetical protein complement(1613754..1615205) Streptococcus equi subsp. zooepidemicus MGCS10565 6761437 YP_002123913.1 CDS Sez_1567 NC_011134.1 1615219 1616373 R similar to ref|YP_001128027.1| RNA methylase family protein [Streptococcus pyogenes str. Manfredo]; methyltransferase; N6-adenine-specific DNA methylase complement(1615219..1616373) Streptococcus equi subsp. zooepidemicus MGCS10565 6761458 YP_002123914.1 CDS Sez_1568 NC_011134.1 1616819 1617142 R similar to ref|YP_280858.1| cell division initiation protein DivIVA [Streptococcus pyogenes MGAS6180]; cell division initiation protein DivIVA complement(1616819..1617142) Streptococcus equi subsp. zooepidemicus MGCS10565 6761434 YP_002123915.1 CDS Sez_1569 NC_011134.1 1617264 1617779 R similar to ref|YP_599079.1| hypothetical cytosolic protein [Streptococcus pyogenes MGAS10270]; hypothetical protein complement(1617264..1617779) Streptococcus equi subsp. zooepidemicus MGCS10565 6761456 YP_002123916.1 CDS recU NC_011134.1 1617855 1618463 D RecU; functions in homologous recombination, DNA repair, and chromosome segregation; binds preferentially to three- and four-stranded DNA intermediates; introduces specific nick sites in four-stranded DNA substrates; functions similarly to Escherichia coli RuvC; Holliday junction-specific endonuclease 1617855..1618463 Streptococcus equi subsp. zooepidemicus MGCS10565 6761429 YP_002123917.1 CDS ponA NC_011134.1 1618525 1620615 D similar to ref|YP_280861.1| multimodular transpeptidase-transglycosylase [Streptococcus pyogenes MGAS6180]; Peptidoglycan synthesis, nascent glycan strand synthesis and cross-linking.; multimodular transpeptidase-transglycosylase; penicillin-binding protein 1A PonA 1618525..1620615 Streptococcus equi subsp. zooepidemicus MGCS10565 6761453 YP_002123918.1 CDS pepC NC_011134.1 1621004 1622341 R similar to ref|YP_280862.1| aminopeptidase C [Streptococcus pyogenes MGAS6180]; Catalysis of the inactivation of bleomycin B2 (a cytotoxic glycometallopeptide) by hydrolysis of a peptide bond of beta-aminoalanine, but also shows general aminopeptidase activity. The specificity varies somewhat with source, but amino acid arylamides of Met, Leu and Ala are preferred.; aminopeptidase complement(1621004..1622341) Streptococcus equi subsp. zooepidemicus MGCS10565 6761451 YP_002123919.1 CDS nadE NC_011134.1 1623038 1623862 R catalyzes the formation of nicotinamide adenine dinucleotide (NAD) from nicotinic acid adenine dinucleotide (NAAD) using either ammonia or glutamine as the amide donor and ATP; ammonia-utilizing enzymes include the ones from Bacillus and Escherichia coli while glutamine-utilizing enzymes include the Mycobacterial one; forms homodimers; NAD synthetase complement(1623038..1623862) Streptococcus equi subsp. zooepidemicus MGCS10565 6761446 YP_002123920.1 CDS Sez_1574 NC_011134.1 1623859 1625319 R catalyzes the formation of 5-phospho-alpha-D-ribose 1-diphosphate and nicotinate from nicotinate D-ribonucleotide and diphosphate; nicotinate phosphoribosyltransferase complement(1623859..1625319) Streptococcus equi subsp. zooepidemicus MGCS10565 6761445 YP_002123921.1 CDS Sez_1575 NC_011134.1 1625298 1625447 R hypothetical protein complement(1625298..1625447) Streptococcus equi subsp. zooepidemicus MGCS10565 6761421 YP_002123922.1 CDS Sez_1576 NC_011134.1 1625595 1627001 R similar to ref|YP_060723.1| Amino acid permease [Streptococcus pyogenes MGAS10394]; amino-acid or metabolite transport protein.; amino acid permease complement(1625595..1627001) Streptococcus equi subsp. zooepidemicus MGCS10565 6761439 YP_002123923.1 CDS trxB NC_011134.1 1627108 1628025 R similar to ref|YP_599086.1| Thioredoxin reductase [Streptococcus pyogenes MGAS10270]; Catalysis of the reaction: thioredoxin + NADP+ = thioredoxin disulfide + NADPH + H+.; thioredoxin reductase complement(1627108..1628025) Streptococcus equi subsp. zooepidemicus MGCS10565 6761349 YP_002123924.1 CDS Sez_1578 NC_011134.1 1628085 1628312 R similar to ref|NP_269700.1| hypothetical protein SPy_1656 [Streptococcus pyogenes M1 GAS]; hypothetical protein complement(1628085..1628312) Streptococcus equi subsp. zooepidemicus MGCS10565 6761413 YP_002123925.1 CDS Sez_1579 NC_011134.1 1628422 1629165 R similar to ref|YP_597089.1| amino acid transport ATP-binding protein [Streptococcus pyogenes MGAS9429]; Probably part of a binding-protein-dependent transport system for an amino acid. Probably responsible for energy coupling to the transport system.; aspartate/glutamate ABC transporter ATP-binding protein complement(1628422..1629165) Streptococcus equi subsp. zooepidemicus MGCS10565 6761412 YP_002123926.1 CDS Sez_1580 NC_011134.1 1629165 1629968 R similar to ref|YP_001128015.1| ABC transporter permease [Streptococcus pyogenes str. Manfredo]; Probably part of a binding-protein-dependent transport system for an amino acid. Probably responsible for the translocation of the substrate across the membrane.; amino-acid ABC transporter permease complement(1629165..1629968) Streptococcus equi subsp. zooepidemicus MGCS10565 6761433 YP_002123927.1 CDS Sez_1581 NC_011134.1 1630133 1630282 D hypothetical protein 1630133..1630282 Streptococcus equi subsp. zooepidemicus MGCS10565 6761403 YP_002123928.1 CDS Sez_1582 NC_011134.1 1630316 1631143 R similar to ref|NP_720902.1| ABC transporter, amino acid binding protein [Streptococcus mutans UA159]; Probably part of the substrate-binding-protein-dependent transport system for an amino acid.; amino-acid ABC transporter extracellular-binding protein precursor complement(1630316..1631143) Streptococcus equi subsp. zooepidemicus MGCS10565 6761402 YP_002123929.1 CDS Sez_1583 NC_011134.1 1631648 1632103 D hypothetical protein 1631648..1632103 Streptococcus equi subsp. zooepidemicus MGCS10565 6761398 YP_002123930.1 CDS Sez_1584 NC_011134.1 1632744 1634087 R similar to ref|YP_060728.1| ATP-dependent RNA helicase [Streptococcus pyogenes MGAS10394]; Has A Helix-Destabilizing Activity. Plays A Key Role In Optimal Cell Growth At Low Temperature And Is Required For Normal Cell Division. Suppressor Of A Mutant Defective In Rpsb Gene For Ribosomal Protein S2.; ATP-dependent RNA helicase DEAD/DEAH box family complement(1632744..1634087) Streptococcus equi subsp. zooepidemicus MGCS10565 6761400 YP_002123931.1 CDS mraY NC_011134.1 1634170 1635177 R First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; phospho-N-acetylmuramoyl-pentapeptide- transferase complement(1634170..1635177) Streptococcus equi subsp. zooepidemicus MGCS10565 6761425 YP_002123932.1 CDS ftsI NC_011134.1 1635179 1637434 R similar to ref|YP_060731.1| Division specific D,D-transpeptidase [Streptococcus pyogenes MGAS10394]; Peptidoglycan synthesis, Catalysis of the reaction: [GlcNAc-(1, 4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)](n)- diphosphoundecaprenol + GlcNAc-(1, 4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)- diphosphoundecaprenol = [GlcNAc-(1, 4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)](n+1)- diphosphoundecaprenol + UDP diphosphate.; cell division protein FtsI complement(1635179..1637434) Streptococcus equi subsp. zooepidemicus MGCS10565 6761424 YP_002123933.1 CDS ftsL NC_011134.1 1637438 1637761 R similar to ref|ZP_00365943.1| COG4839: Protein required for the initiation of cell division [Streptococcus pyogenes M49 591]; Involved in initiation of cell division.; FtsL protein complement(1637438..1637761) Streptococcus equi subsp. zooepidemicus MGCS10565 6761426 YP_002123934.1 CDS mraW NC_011134.1 1637765 1638715 R similar to sp|Q5XAL3|MRAW_STRP6 S-adenosyl-L-methionine-dependent methyltransferase mraW; S-adenosyl-methyltransferase MraW complement(1637765..1638715) Streptococcus equi subsp. zooepidemicus MGCS10565 6761396 YP_002123935.1 CDS Sez_1589 NC_011134.1 1638818 1639234 R similar to ref|NP_607720.1| hypothetical protein spyM18_1678 [Streptococcus pyogenes MGAS8232]; hypothetical protein complement(1638818..1639234) Streptococcus equi subsp. zooepidemicus MGCS10565 6761420 YP_002123936.1 CDS proA NC_011134.1 1639254 1640504 R Catalyzes the phosphorylation of L-glutamate during the proline biosynthesis pathway; gamma-glutamyl phosphate reductase complement(1639254..1640504) Streptococcus equi subsp. zooepidemicus MGCS10565 6761419 YP_002123937.1 CDS proB NC_011134.1 1640501 1641319 R catalyzes the formation of glutamate 5-phosphate from glutamate in proline biosynthesis; gamma-glutamyl kinase complement(1640501..1641319) Streptococcus equi subsp. zooepidemicus MGCS10565 6761417 YP_002123938.1 CDS Sez_1592 NC_011134.1 1641930 1643048 D similar to ref|YP_001198821.1| hypothetical protein SSU05_1455 [Streptococcus suis 05ZYH33]; hypothetical protein 1641930..1643048 Streptococcus equi subsp. zooepidemicus MGCS10565 6761410 YP_002123939.1 CDS Sez_1593 NC_011134.1 1643214 1643384 R hypothetical protein complement(1643214..1643384) Streptococcus equi subsp. zooepidemicus MGCS10565 6761409 YP_002123940.1 CDS Sez_1594 NC_011134.1 1643567 1645195 R similar to ref|YP_282735.1| ABC transporter permease [Streptococcus pyogenes MGAS5005]; ABC transporter permease complement(1643567..1645195) Streptococcus equi subsp. zooepidemicus MGCS10565 6761384 YP_002123941.1 CDS Sez_1595 NC_011134.1 1645200 1645658 R similar to ref|NP_269711.1| ABC transporter (ATP-binding protein) [Streptococcus pyogenes M1 GAS]; Facilitated transport; ABC transporter ATP-binding protein complement(1645200..1645658) Streptococcus equi subsp. zooepidemicus MGCS10565 6761405 YP_002123942.1 CDS Sez_1596 NC_011134.1 1645615 1645932 R similar to ref|YP_602977.1| ABC transporter ATP-binding protein [Streptococcus pyogenes MGAS10750]; Facilitated transport; ABC transporter ATP-binding protein complement(1645615..1645932) Streptococcus equi subsp. zooepidemicus MGCS10565 6761404 YP_002123943.1 CDS Sez_1597 NC_011134.1 1645978 1646235 R similar to ref|YP_282737.1| hypothetical protein M5005_Spy_1374 [Streptococcus pyogenes MGAS5005]; hypothetical protein complement(1645978..1646235) Streptococcus equi subsp. zooepidemicus MGCS10565 6761383 YP_002123944.1 CDS tkt NC_011134.1 1648232 1650220 R catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase; transketolase complement(1648232..1650220) Streptococcus equi subsp. zooepidemicus MGCS10565 6761375 YP_002123945.1 CDS Sez_1601 NC_011134.1 1650434 1650571 R hypothetical protein complement(1650434..1650571) Streptococcus equi subsp. zooepidemicus MGCS10565 6761371 YP_002123946.1 CDS tal NC_011134.1 1650605 1651249 R similar to novel fructose-6-phosphate aldolase from Escherichia coli; enzyme from Methanocaldococcus janaschii shows transaldolase activity; translaldolase complement(1650605..1651249) Streptococcus equi subsp. zooepidemicus MGCS10565 6761369 YP_002123947.1 CDS glpK NC_011134.1 1651423 1652928 R Converts glycerol and ADP to glycerol-3-phosphate and ADP; glycerol kinase complement(1651423..1652928) Streptococcus equi subsp. zooepidemicus MGCS10565 6761393 YP_002123948.1 CDS Sez_1604 NC_011134.1 1653030 1653182 R hypothetical protein complement(1653030..1653182) Streptococcus equi subsp. zooepidemicus MGCS10565 6761365 YP_002123949.1 CDS Sez_1605 NC_011134.1 1653266 1653847 R similar to ref|YP_001127997.1| lipoprotein [Streptococcus pyogenes str. Manfredo]; hypothetical protein complement(1653266..1653847) Streptococcus equi subsp. zooepidemicus MGCS10565 6761391 YP_002123950.1 CDS Sez_1606 NC_011134.1 1654772 1654966 R similar to gb|AAM90904.2|AF493605_7 BlpM-like protein [Streptococcus pyogenes]; bacteriocin-like peptide complement(1654772..1654966) Streptococcus equi subsp. zooepidemicus MGCS10565 6761362 YP_002123951.1 CDS Sez_1607 NC_011134.1 1655473 1656339 R similar to ref|YP_281699.1| corrin/porphyrin methyltransferase [Streptococcus pyogenes MGAS5005]; tetrapyrrole (corrin-porphyrin) methylase family protein complement(1655473..1656339) Streptococcus equi subsp. zooepidemicus MGCS10565 6761382 YP_002123952.1 CDS yabA NC_011134.1 1656344 1656667 R in Bacillus subtilis this protein is involved in the negative regulation of DNA replication initiation; interacts with DnaN and DnaA; DNA replication intiation control protein YabA complement(1656344..1656667) Streptococcus equi subsp. zooepidemicus MGCS10565 6761380 YP_002123953.1 CDS yaaT NC_011134.1 1656660 1657460 R similar to ref|NP_721994.1| signal peptidase II [Streptococcus mutans UA159]; Essential for the phosphorelay during initiation of sporulation. May control the level of phosphorylated spo0A through spo0E activity during sporulation.; stage 0 sporulation protein YaaT-like complement(1656660..1657460) Streptococcus equi subsp. zooepidemicus MGCS10565 6761619 YP_002123954.1 CDS holB NC_011134.1 1657457 1658332 R catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the delta' subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA.; DNA polymerase III subunit delta' complement(1657457..1658332) Streptococcus equi subsp. zooepidemicus MGCS10565 6761591 YP_002123955.1 CDS tmk NC_011134.1 1658346 1659044 R catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to thymidine monophosphate (dTMP) to form thymidine diphosphate (dTDP); thymidylate kinase complement(1658346..1659044) Streptococcus equi subsp. zooepidemicus MGCS10565 6761616 YP_002123956.1 CDS Sez_1612 NC_011134.1 1659297 1659581 R similar to ref|YP_596061.1| hypothetical protein MGAS9429_Spy0329 [Streptococcus pyogenes MGAS9429]; hypothetical protein complement(1659297..1659581) Streptococcus equi subsp. zooepidemicus MGCS10565 6761609 YP_002123957.1 CDS Sez_1613 NC_011134.1 1659582 1660028 R similar to ref|NP_722004.1| hypothetical protein SMU.1671c [Streptococcus mutans UA159]; hypothetical protein complement(1659582..1660028) Streptococcus equi subsp. zooepidemicus MGCS10565 6761606 YP_002123958.1 CDS clpP NC_011134.1 1660133 1660756 R hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates; ATP-dependent Clp protease proteolytic subunit complement(1660133..1660756) Streptococcus equi subsp. zooepidemicus MGCS10565 6761605 YP_002123959.1 CDS upp NC_011134.1 1660955 1661584 R Catalyzes the formation of uracil and 5-phospho-alpha-D-ribosy 1-diphosphate from UMP and diphosphate; uracil phosphoribosyltransferase complement(1660955..1661584) Streptococcus equi subsp. zooepidemicus MGCS10565 6761579 YP_002123960.1 CDS Sez_1616 NC_011134.1 1661734 1663365 R similar to ref|YP_059670.1| Export protein for polysaccharides and teichoic acids [Streptococcus pyogenes MGAS10394]; export protein for polysaccharides and teichoic acids complement(1661734..1663365) Streptococcus equi subsp. zooepidemicus MGCS10565 6761601 YP_002123961.1 CDS murE NC_011134.1 1663451 1664896 D involved in cell wall formation; peptidoglycan synthesis; cytoplasmic enzyme; catalyzes the addition of lysine to UDP-N-acetylmuramoyl-L-alanyl-D-glutamate forming UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysine; UDP-N-acetylmuramoylalanyl-D-glutamate--L-lysine ligase 1663451..1664896 Streptococcus equi subsp. zooepidemicus MGCS10565 6761599 YP_002123962.1 CDS fhuC NC_011134.1 1665156 1665935 D similar to ref|ZP_00365817.1| COG1120: ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components [Streptococcus pyogenes M49 591]; Part of the binding-protein-dependent transport system for Fe(3+)-ferrichrome. Probably responsible for energy coupling to the transport system.; ferrichrome ABC transporter ATP-binding protein 1665156..1665935 Streptococcus equi subsp. zooepidemicus MGCS10565 6761598 YP_002123963.1 CDS fhuD NC_011134.1 1665960 1666898 D similar to ref|NP_268705.1| ferrichrome ABC transporter (ferrichrome-binding protein) [Streptococcus pyogenes M1 GAS]; This is one of the proteins involved in the high-affinity transport of Fe(3+)-ferrichrome into the cell.; ferrichrome-binding lipoprotein precursor FhuD 1665960..1666898 Streptococcus equi subsp. zooepidemicus MGCS10565 6761574 YP_002123964.1 CDS fhuB NC_011134.1 1666882 1667934 D similar to ref|YP_001129059.1| ferrichrome transport permease [Streptococcus pyogenes str. Manfredo]; This is one of the proteins involved in the high- affinity transport of Fe(3+)-ferrichrome into the cell.; ferrichrome ABC transporter permease 1666882..1667934 Streptococcus equi subsp. zooepidemicus MGCS10565 6761593 YP_002123965.1 CDS fhuG NC_011134.1 1667931 1668929 D similar to ref|NP_802841.1| ferrichrome ABC transporter (permease) [Streptococcus pyogenes SSI-1]; This is one of the proteins involved in the high- affinity transport of Fe(3+)-ferrichrome into the cell.; ferrichrome ABC transporter permease 1667931..1668929 Streptococcus equi subsp. zooepidemicus MGCS10565 6761592 YP_002123966.1 CDS Sez_1622 NC_011134.1 1669309 1669437 D hypothetical protein 1669309..1669437 Streptococcus equi subsp. zooepidemicus MGCS10565 6761521 YP_002123967.1 CDS Sez_1623 NC_011134.1 1669666 1670319 R similar to ref|YP_601808.1| hypothetical cytosolic protein [Streptococcus pyogenes MGAS10750]; hypothetical protein complement(1669666..1670319) Streptococcus equi subsp. zooepidemicus MGCS10565 6761586 YP_002123968.1 CDS Sez_1624 NC_011134.1 1670386 1671321 R catalyzes the hydrolysis of pyrophosphate to phosphate; manganese-dependent inorganic pyrophosphatase complement(1670386..1671321) Streptococcus equi subsp. zooepidemicus MGCS10565 6761584 YP_002123969.1 CDS Sez_1625 NC_011134.1 1671806 1672597 R similar to ref|NP_606672.1| pyruvate-formatelyase activating enzyme [Streptococcus pyogenes MGAS8232]; Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.; pyruvate formate-lyase-activating enzyme complement(1671806..1672597) Streptococcus equi subsp. zooepidemicus MGCS10565 6761578 YP_002123970.1 CDS Sez_1626 NC_011134.1 1672674 1674008 R similar to ref|YP_279775.1| hemolysin [Streptococcus pyogenes MGAS6180]; hemolysins and related proteins containing CBS domains, magnesium and cobalt efflux protein complement(1672674..1674008) Streptococcus equi subsp. zooepidemicus MGCS10565 6761576 YP_002123971.1 CDS Sez_1627 NC_011134.1 1674136 1674693 R similar to ref|YP_279774.1| SAM-dependent methyltransferase [Streptococcus pyogenes MGAS6180]; SAM-dependent methyltransferase complement(1674136..1674693) Streptococcus equi subsp. zooepidemicus MGCS10565 6761577 YP_002123972.1 CDS Sez_1628 NC_011134.1 1674703 1675428 R similar to ref|YP_194206.1| kanamycin kinase [Lactobacillus acidophilus NCFM]; aminoglycoside 3'-phosphotransferase complement(1674703..1675428) Streptococcus equi subsp. zooepidemicus MGCS10565 6761575 YP_002123973.1 CDS Sez_1629 NC_011134.1 1675501 1676424 R similar to ref|YP_596046.1| radical SAM superfamily protein [Streptococcus pyogenes MGAS9429]; Fe-S oxidoreductase complement(1675501..1676424) Streptococcus equi subsp. zooepidemicus MGCS10565 6761573 YP_002123974.1 CDS Sez_1630 NC_011134.1 1676616 1677239 R similar to ref|YP_596045.1| membrane-associated phospholipid phosphatase [Streptococcus pyogenes MGAS9429]; membrane-associated phospholipid phosphatase PAP2 Family Protein complement(1676616..1677239) Streptococcus equi subsp. zooepidemicus MGCS10565 6761554 YP_002123975.1 CDS ypaA NC_011134.1 1677253 1677855 R similar to ref|YP_279771.1| riboflavin transporter [Streptococcus pyogenes MGAS6180]; riboflavin transporter YpaA-like complement(1677253..1677855) Streptococcus equi subsp. zooepidemicus MGCS10565 6761571 YP_002123976.1 CDS Sez_1632 NC_011134.1 1678617 1678931 R similar to ref|ZP_00785752.1| Unknown [Streptococcus agalactiae COH1]; hypothetical protein complement(1678617..1678931) Streptococcus equi subsp. zooepidemicus MGCS10565 6761572 YP_002123977.1 CDS Sez_1633 NC_011134.1 1678921 1680117 R similar to ref|NP_736400.1| hypothetical protein gbs1967 [Streptococcus agalactiae NEM316]; hypothetical protein complement(1678921..1680117) Streptococcus equi subsp. zooepidemicus MGCS10565 6761551 YP_002123978.1 CDS Sez_1634 NC_011134.1 1680594 1680893 R similar to ref|YP_849451.1| hypothetical protein lwe1254 [Listeria welshimeri serovar 6b str. SLCC5334]; hypothetical protein complement(1680594..1680893) Streptococcus equi subsp. zooepidemicus MGCS10565 6761550 YP_002123979.1 CDS Sez_1635 NC_011134.1 1681215 1681505 R similar to ref|ZP_00874487.1| similar to unknown proteins [Streptococcus suis 89/1591]; hypothetical protein complement(1681215..1681505) Streptococcus equi subsp. zooepidemicus MGCS10565 6761546 YP_002123980.1 CDS Sez_1636 NC_011134.1 1681502 1681870 R similar to ref|NP_736401.1| hypothetical protein gbs1968 [Streptococcus agalactiae NEM316]; hypothetical protein complement(1681502..1681870) Streptococcus equi subsp. zooepidemicus MGCS10565 6761562 YP_002123981.1 CDS Sez_1637 NC_011134.1 1682177 1682599 R similar to ref|NP_736401.1| hypothetical protein gbs1968 [Streptococcus agalactiae NEM316]; hypothetical protein complement(1682177..1682599) Streptococcus equi subsp. zooepidemicus MGCS10565 6761534 YP_002123982.1 CDS Sez_1638 NC_011134.1 1682979 1683578 R similar to ref|YP_059656.1| 23S rRNA methyltransferase [Streptococcus pyogenes MGAS10394]; tRNA (cytosine34-2'-O-)-methyltransferase complement(1682979..1683578) Streptococcus equi subsp. zooepidemicus MGCS10565 6761540 YP_002123983.1 CDS Sez_1639 NC_011134.1 1683686 1683964 R similar to ref|NP_606663.1| hypothetical protein spyM18_0419 [Streptococcus pyogenes MGAS8232]; hypothetical protein complement(1683686..1683964) Streptococcus equi subsp. zooepidemicus MGCS10565 6761558 YP_002123984.1 CDS rluB NC_011134.1 1683961 1684761 R similar to ref|YP_279768.1| ribosomal large subunit pseudouridine synthase B [Streptococcus pyogenes MGAS6180]; Responsible for synthesis of pseudouridine from uracil- 2633 in 23S ribosomal RNA.; ribosomal large subunit pseudouridine synthase B RluB complement(1683961..1684761) Streptococcus equi subsp. zooepidemicus MGCS10565 6761555 YP_002123985.1 CDS scpB NC_011134.1 1684929 1685468 R functions during chromosome segregation; may form a condensin-like structure with SMC and ScpA; forms a homodimer; segregation and condensation protein B complement(1684929..1685468) Streptococcus equi subsp. zooepidemicus MGCS10565 6761530 YP_002123986.1 CDS scpA NC_011134.1 1685465 1686172 R functions during chromosome segregation; may form a condensin-like structure with SMC and ScpB; segregation and condensation protein A complement(1685465..1686172) Streptococcus equi subsp. zooepidemicus MGCS10565 6761549 YP_002123987.1 CDS xerD NC_011134.1 1686172 1686918 R site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs; site-specific tyrosine recombinase XerD complement(1686172..1686918) Streptococcus equi subsp. zooepidemicus MGCS10565 6761520 YP_002123988.1 CDS Sez_1644 NC_011134.1 1686915 1687376 R similar to ref|YP_279764.1| CBS domain containing protein [Streptococcus pyogenes MGAS6180]; hypothetical protein complement(1686915..1687376) Streptococcus equi subsp. zooepidemicus MGCS10565 6761547 YP_002123989.1 CDS Sez_1645 NC_011134.1 1687373 1687870 R similar to ref|ZP_00366310.1| COG0622: Predicted phosphoesterase [Streptococcus pyogenes M49 591]; metallophosphoesterase complement(1687373..1687870) Streptococcus equi subsp. zooepidemicus MGCS10565 6761544 YP_002123990.1 CDS Sez_1646 NC_011134.1 1687870 1688859 R HAM1-like protein; Rec-dependent growth; RgdB; yggV; it is suspected that this protein functions to remove misincorporated bases such as xanthine or hypoxanthine; deoxyribonucleotide triphosphate pyrophosphatase/hypothetical protein complement(1687870..1688859) Streptococcus equi subsp. zooepidemicus MGCS10565 6761541 YP_002123991.1 CDS murI NC_011134.1 1688856 1689734 R converts L-glutamate to D-glutamate, a component of peptidoglycan; glutamate racemase complement(1688856..1689734) Streptococcus equi subsp. zooepidemicus MGCS10565 6761535 YP_002123992.1 CDS Sez_1648 NC_011134.1 1689830 1690072 R similar to ref|NP_268684.1| hypothetical protein SPy_0359 [Streptococcus pyogenes M1 GAS]; hypothetical protein complement(1689830..1690072) Streptococcus equi subsp. zooepidemicus MGCS10565 6761536 YP_002123993.1 CDS Sez_1649 NC_011134.1 1690470 1691162 R similar to ref|ZP_00366306.1| COG0670: Integral membrane protein, interacts with FtsH [Streptococcus pyogenes M49 591]; hypothetical protein complement(1690470..1691162) Streptococcus equi subsp. zooepidemicus MGCS10565 6761539 YP_002123994.1 CDS Sez_1650 NC_011134.1 1691178 1691678 R similar to ref|YP_597903.1| Hydrolase [Streptococcus pyogenes MGAS10270]; hydrolase complement(1691178..1691678) Streptococcus equi subsp. zooepidemicus MGCS10565 6761531 YP_002123995.1 CDS Sez_1651 NC_011134.1 1691716 1692453 R similar to ref|NP_664062.1| spoU rRNA Methylase family protein [Streptococcus pyogenes MGAS315]; RNA methyltransferase TrmH family complement(1691716..1692453) Streptococcus equi subsp. zooepidemicus MGCS10565 6761528 YP_002123996.1 CDS Sez_1652 NC_011134.1 1692844 1694565 D similar to ref|ZP_01371554.1| transposase, IS4 [Desulfitobacterium hafniense DCB-2]; transposase IS4-like 1692844..1694565 Streptococcus equi subsp. zooepidemicus MGCS10565 6761499 YP_002123997.1 CDS Sez_1653 NC_011134.1 1694913 1695191 D catalyzes the hydrolysis of acylphosphate; acylphosphatase 1694913..1695191 Streptococcus equi subsp. zooepidemicus MGCS10565 6761518 YP_002123998.1 CDS oxaA2 NC_011134.1 1695274 1696194 D involved in biogenesis of membrane proteins; Firmicutes specific proteins are shorter than other bacterial counterparts and have a signal peptide and lipid attachment site; OxaA-like protein precursor 1695274..1696194 Streptococcus equi subsp. zooepidemicus MGCS10565 6761517 YP_002123999.1 CDS greA NC_011134.1 1696451 1696981 R necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus; transcription elongation factor GreA complement(1696451..1696981) Streptococcus equi subsp. zooepidemicus MGCS10565 6761516 YP_002124000.1 CDS Sez_1656 NC_011134.1 1697006 1698574 R similar to ref|ZP_00366469.1| COG1559: Predicted periplasmic solute-binding protein [Streptococcus pyogenes M49 591]; aminodeoxychorismate lyase complement(1697006..1698574) Streptococcus equi subsp. zooepidemicus MGCS10565 6761515 YP_002124001.1 CDS Sez_1657 NC_011134.1 1698671 1699150 R similar to ref|ZP_00366468.1| COG0454: Histone acetyltransferase HPA2 and related acetyltransferases [Streptococcus pyogenes M49 591]; arylalkylamine n-acetyltransferase complement(1698671..1699150) Streptococcus equi subsp. zooepidemicus MGCS10565 6761514 YP_002124002.1 CDS murC NC_011134.1 1699213 1700544 R Catalyzes the formation of UDP-N-acetylmuramoyl-L-alanine from UDP-N-acetylmuramate and L-alanine in peptidoglycan synthesis; UDP-N-acetylmuramate--L-alanine ligase complement(1699213..1700544) Streptococcus equi subsp. zooepidemicus MGCS10565 6761513 YP_002124003.1 CDS Sez_1659 NC_011134.1 1700588 1701181 R similar to ref|NP_268674.1| hypothetical protein SPy_0343 [Streptococcus pyogenes M1 GAS]; hypothetical protein complement(1700588..1701181) Streptococcus equi subsp. zooepidemicus MGCS10565 6761512 YP_002124004.1 CDS Sez_1660 NC_011134.1 1701385 1704489 R similar to ref|YP_059634.1| SWF/SNF family helicase [Streptococcus pyogenes MGAS10394]; SWF/SNF family helicase complement(1701385..1704489) Streptococcus equi subsp. zooepidemicus MGCS10565 6761511 YP_002124005.1 CDS engA NC_011134.1 1704818 1706158 R EngA; essential Neisserial GTPase; synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains; GTP-binding protein EngA complement(1704818..1706158) Streptococcus equi subsp. zooepidemicus MGCS10565 6761509 YP_002124006.1 CDS dnaI NC_011134.1 1706178 1707086 R Primosomal protein that may act to load helicase DnaC during DNA replication; primosomal protein DnaI complement(1706178..1707086) Streptococcus equi subsp. zooepidemicus MGCS10565 6761503 YP_002124007.1 CDS dnaB NC_011134.1 1707087 1708247 R similar to ref|YP_059631.1| Replicative DNA helicase [Streptococcus pyogenes MGAS10394]; helicase loader DnaB complement(1707087..1708247) Streptococcus equi subsp. zooepidemicus MGCS10565 6761502 YP_002124008.1 CDS nrdR NC_011134.1 1708234 1708728 R similar to sp|Q5XDR6|NRDR_STRP6 Transcriptional repressor nrdR; NrdR family transcriptional regulator complement(1708234..1708728) Streptococcus equi subsp. zooepidemicus MGCS10565 6761497 YP_002124009.1 CDS covS NC_011134.1 1708919 1710409 R similar to ref|NP_802876.1| two-component sensor histidine kinase (CsrS/CovS) [Streptococcus pyogenes SSI-1]; Member of the two-component regulatory system CovR/CovS involved in the regulation of multiple virulence factors.; TCS sensor kinase CovS-like complement(1708919..1710409) Streptococcus equi subsp. zooepidemicus MGCS10565 6761496 YP_002124010.1 CDS covR NC_011134.1 1710413 1711099 R similar to ref|NP_802877.1| two-component response regulator (CsrR/CovR) [Streptococcus pyogenes SSI-1]; Member of the two-component regulatory system CovR/CovS involved in the regulation of multiple virulence factors.; TCS response regulator CovR-like complement(1710413..1711099) Streptococcus equi subsp. zooepidemicus MGCS10565 6761495 YP_002124011.1 CDS Sez_1667 NC_011134.1 1711285 1711818 R similar to ref|YP_001129097.1| hypothetical protein SpyM51574 [Streptococcus pyogenes str. Manfredo]; hypothetical protein complement(1711285..1711818) Streptococcus equi subsp. zooepidemicus MGCS10565 6761488 YP_002124012.1 CDS htpX NC_011134.1 1712106 1712999 R metalloprotease; heat shock protein HtpX complement(1712106..1712999) Streptococcus equi subsp. zooepidemicus MGCS10565 6762329 YP_002124013.1 CDS Sez_1669 NC_011134.1 1713031 1713582 R similar to ref|YP_001129099.1| LemA family protein [Streptococcus pyogenes str. Manfredo]; cytoplasmic membrane protein LemA complement(1713031..1713582) Streptococcus equi subsp. zooepidemicus MGCS10565 6761374 YP_002124014.1 CDS gidB NC_011134.1 1713724 1714437 D glucose-inhibited division protein B; SAM-dependent methyltransferase; methylates the N7 position of guanosine in position 527 of 16S rRNA; 16S rRNA methyltransferase GidB 1713724..1714437 Streptococcus equi subsp. zooepidemicus MGCS10565 6761875 YP_002124015.1 CDS ktrB NC_011134.1 1714971 1716347 D similar to ref|YP_601766.1| Potassium uptake protein ktrB [Streptococcus pyogenes MGAS10750]; potassium uptake protein KtrB 1714971..1716347 Streptococcus equi subsp. zooepidemicus MGCS10565 6762222 YP_002124016.1 CDS ktrA NC_011134.1 1716357 1717031 D similar to ref|YP_601765.1| Potassium uptake protein ktrA [Streptococcus pyogenes MGAS10750]; potassium uptake protein KtrA 1716357..1717031 Streptococcus equi subsp. zooepidemicus MGCS10565 6760834 YP_002124017.1 CDS Sez_1673 NC_011134.1 1717224 1718438 R involved in the import of serine and threonine coupled with the import of sodium; serine/threonine transporter SstT complement(1717224..1718438) Streptococcus equi subsp. zooepidemicus MGCS10565 6760393 YP_002124018.1 CDS metI NC_011134.1 1720297 1720989 R similar to ref|NP_664039.1| ABC transporter (permease) [Streptococcus pyogenes MGAS315]; Part of the binding-protein-dependent transport system for D-methionine. Probably responsible for the translocation of the substrate across the membrane.; D-methionine transport system permease MetI complement(1720297..1720989) Streptococcus equi subsp. zooepidemicus MGCS10565 6760819 YP_002124019.1 CDS metN NC_011134.1 1720990 1722042 R similar to ref|YP_596003.1| ABC transporter ATP-binding protein [Streptococcus pyogenes MGAS9429]; Part of the binding-protein-dependent transport system metNIQ for D-methionine and the toxic methionine analog alpha- methyl-methionine. Probably responsible for energy coupling to the transport system.; D-methionine transport ATP-binding protein MetN complement(1720990..1722042) Streptococcus equi subsp. zooepidemicus MGCS10565 6760656 YP_002124020.1 CDS Sez_1678 NC_011134.1 1722047 1723417 R similar to gb|AAN59550.1|AE015018_4 peptidase, AtmC; ArgE/DapE/Acy1 family protein [Streptococcus mutans UA159]; Catalysis of the reaction: N-acyl-L-amino acid + H2O = carboxylate + L-amino acid.; N-acyl-L-amino acid amidohydrolase complement(1722047..1723417) Streptococcus equi subsp. zooepidemicus MGCS10565 6760377 YP_002124021.1 CDS metQ NC_011134.1 1723490 1724335 R similar to ref|YP_279732.1| ABC transporter substrate-binding protein [Streptococcus pyogenes MGAS6180]; This protein is a component of a D-methionine permease, a binding protein-dependent, ATP-driven transport system.; D-methionine-binding lipoprotein MetQ complement(1723490..1724335) Streptococcus equi subsp. zooepidemicus MGCS10565 6760486 YP_002124022.1 CDS Sez_1680 NC_011134.1 1724696 1725541 R similar to ref|YP_059616.1| ABC transporter substrate-binding protein [Streptococcus pyogenes MGAS10394]; Probably part of a binding-protein-dependent transport system for an amino acid.; amino-acid ABC transporter-binding lipoprotein precursor complement(1724696..1725541) Streptococcus equi subsp. zooepidemicus MGCS10565 6760815 YP_002124023.1 CDS Sez_1681 NC_011134.1 1725763 1726479 R similar to ref|YP_059615.1| hypothetical protein M6_Spy0297 [Streptococcus pyogenes MGAS10394]; hypothetical protein complement(1725763..1726479) Streptococcus equi subsp. zooepidemicus MGCS10565 6760462 YP_002124024.1 CDS Sez_1682 NC_011134.1 1726620 1727390 R similar to ref|ZP_00790359.1| MerR family transcriptional regulator [Streptococcus agalactiae 515]; Transcriptional activator.; MerR family transcriptional regulator complement(1726620..1727390) Streptococcus equi subsp. zooepidemicus MGCS10565 6760472 YP_002124025.1 CDS Sez_1683 NC_011134.1 1727691 1728791 R similar to ref|YP_595998.1| hypothetical cytosolic protein [Streptococcus pyogenes MGAS9429]; hypothetical protein complement(1727691..1728791) Streptococcus equi subsp. zooepidemicus MGCS10565 6760428 YP_002124026.1 CDS Sez_1684 NC_011134.1 1728901 1729644 R similar to ref|YP_281630.1| methyltransferase [Streptococcus pyogenes MGAS5005]; ubiquinone/menaquinone biosynthesis methyltransferase complement(1728901..1729644) Streptococcus equi subsp. zooepidemicus MGCS10565 6760843 YP_002124027.1 CDS Sez_1685 NC_011134.1 1729774 1730127 R similar to ref|YP_601754.1| iojap protein family [Streptococcus pyogenes MGAS10750]; Iojap-related protein complement(1729774..1730127) Streptococcus equi subsp. zooepidemicus MGCS10565 6760852 YP_002124028.1 CDS Sez_1686 NC_011134.1 1730129 1730719 R similar to ref|ZP_00366134.1| COG1713: Predicted HD superfamily hydrolase involved in NAD metabolism [Streptococcus pyogenes M49 591]; hydrolase HAD superfamily complement(1730129..1730719) Streptococcus equi subsp. zooepidemicus MGCS10565 6762192 YP_002124029.1 CDS nadD NC_011134.1 1730719 1731318 R transfers an adenyl group from ATP to NaMN to form nicotinic acid adenine dinucleotide (NaAD) which is then converted to the ubiquitous compound NAD by NAD synthetase; essential enzyme in bacteria; nicotinic acid mononucleotide adenylyltransferase complement(1730719..1731318) Streptococcus equi subsp. zooepidemicus MGCS10565 6762203 YP_002124030.1 CDS Sez_1688 NC_011134.1 1731435 1731743 R similar to ref|YP_059608.1| Hypothetical RNA binding protein [Streptococcus pyogenes MGAS10394]; RNA binding protein complement(1731435..1731743) Streptococcus equi subsp. zooepidemicus MGCS10565 6762201 YP_002124031.1 CDS Sez_1689 NC_011134.1 1731770 1732888 R in Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis; GTP-binding protein YqeH complement(1731770..1732888) Streptococcus equi subsp. zooepidemicus MGCS10565 6762198 YP_002124032.1 CDS Sez_1690 NC_011134.1 1732888 1733460 R similar to ref|ZP_00365601.1| COG2179: Predicted hydrolase of the HAD superfamily [Streptococcus pyogenes M49 591]; hydrolase HAD subfamily IIIA complement(1732888..1733460) Streptococcus equi subsp. zooepidemicus MGCS10565 6762191 YP_002124033.1 CDS comX NC_011134.1 1733559 1734038 R similar to ref|NP_664024.1| transcriptional regulator ComX1 [Streptococcus pyogenes MGAS315]; Involved in establishing competence.; competence-specific sigma factor ComX complement(1733559..1734038) Streptococcus equi subsp. zooepidemicus MGCS10565 6762187 YP_002124034.1 CDS Sez_1692 NC_011134.1 1734275 1734412 R hypothetical protein complement(1734275..1734412) Streptococcus equi subsp. zooepidemicus MGCS10565 6761191 YP_002124035.1 CDS oppF NC_011134.1 1739969 1740892 R similar to ref|YP_597862.1| Oligopeptide transport ATP-binding protein oppF [Streptococcus pyogenes MGAS10270]; Part of the binding-protein-dependent transport system for oligopeptides. Probably responsible for energy coupling to the transport system.; oligopeptide transport ATP-binding protein OppF complement(1739969..1740892) Streptococcus equi subsp. zooepidemicus MGCS10565 6761115 YP_002124036.1 CDS oppD NC_011134.1 1740885 1741955 R similar to ref|YP_601743.1| Oligopeptide transport ATP-binding protein oppD [Streptococcus pyogenes MGAS10750]; Part of the binding-protein-dependent transport system for oligopeptides. Probably responsible for energy coupling to the transport system.; oligopeptide transport ATP-binding protein OppD complement(1740885..1741955) Streptococcus equi subsp. zooepidemicus MGCS10565 6762164 YP_002124037.1 CDS oppC NC_011134.1 1741964 1742890 R similar to ref|YP_599868.1| Oligopeptide transport system permease oppC [Streptococcus pyogenes MGAS2096]; Part of the binding-protein-dependent transport system for oligopeptides; probably responsible for the translocation of the substrate across the membrane.; oligopeptide transport system permease OppC complement(1741964..1742890) Streptococcus equi subsp. zooepidemicus MGCS10565 6762162 YP_002124038.1 CDS oppB NC_011134.1 1742890 1744389 R similar to ref|YP_001035872.1| Oligopeptide transport system permease, [Streptococcus sanguinis SK36]; Part of the binding-protein-dependent transport system for oligopeptides; probably responsible for the translocation of the substrate across the membrane.; oligopeptide transport system permease OppB complement(1742890..1744389) Streptococcus equi subsp. zooepidemicus MGCS10565 6762152 YP_002124039.1 CDS oppA NC_011134.1 1744453 1746429 R similar to ref|YP_001127821.1| extracellular oligopeptide-binding protein [Streptococcus pyogenes str. Manfredo]; Part of the binding-protein-dependent transport system for oligopeptides; probably an oligopeptide binding protein.; oligopeptide ABC transporter periplasmic oligopeptide-binding protein OppA complement(1744453..1746429) Streptococcus equi subsp. zooepidemicus MGCS10565 6762156 YP_002124040.1 CDS dacA.1 NC_011134.1 1746689 1747975 D similar to ref|YP_001127820.1| D-alanyl-D-alanine carboxypeptidase [Streptococcus pyogenes str. Manfredo]; Removes C-terminal D-alanyl residues from sugar-peptide cell wall peptidoglycan precursors.; D-alanyl-D-alanine carboxypeptidase 1746689..1747975 Streptococcus equi subsp. zooepidemicus MGCS10565 6762149 YP_002124041.1 CDS dacA.2 NC_011134.1 1748299 1749534 D similar to ref|NP_687183.1| D-alanyl-D-alanine carboxypeptidase family protein [Streptococcus agalactiae 2603V/R]; Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.; D-alanyl-D-alanine carboxypeptidase 1748299..1749534 Streptococcus equi subsp. zooepidemicus MGCS10565 6762126 YP_002124042.1 CDS dacA.3 NC_011134.1 1749618 1750799 D similar to ref|YP_597856.1| D-alanyl-D-alanine carboxypeptidase [Streptococcus pyogenes MGAS10270]; Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.; D-alanyl-D-alanine carboxypeptidase 1749618..1750799 Streptococcus equi subsp. zooepidemicus MGCS10565 6762141 YP_002124043.1 CDS sufB NC_011134.1 1750959 1752377 R similar to ref|ZP_00365646.1| COG0719: ABC-type transport system involved in Fe-S cluster assembly, permease component [Streptococcus pyogenes M49; iron-sulfur cluster assembly protein SufB complement(1750959..1752377) Streptococcus equi subsp. zooepidemicus MGCS10565 6762137 YP_002124044.1 CDS iscU NC_011134.1 1752417 1752824 R similar to ref|YP_281609.1| iscU protein [Streptococcus pyogenes MGAS5005]; May be involved in the formation or repair of [Fe-S] clusters present in iron-sulfur proteins (potential).; iron-sulfur cluster assembly scaffold protein IscU complement(1752417..1752824) Streptococcus equi subsp. zooepidemicus MGCS10565 6762113 YP_002124045.1 CDS sufS NC_011134.1 1752841 1754067 R similar to ref|YP_059593.1| Cysteine desulfhydrase [Streptococcus pyogenes MGAS10394]; Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine.; cysteine desulfurase complement(1752841..1754067) Streptococcus equi subsp. zooepidemicus MGCS10565 6762106 YP_002124046.1 CDS sufD NC_011134.1 1754094 1755356 R similar to ref|ZP_00366219.1| COG0719: ABC-type transport system involved in Fe-S cluster assembly, permease component [Streptococcus pyogenes M49 591]; iron-sulfur cluster assembly protein SufD complement(1754094..1755356) Streptococcus equi subsp. zooepidemicus MGCS10565 6762081 YP_002124047.1 CDS sufC NC_011134.1 1755448 1756218 R similar to ref|YP_279706.1| ABC transporter ATP-binding protein [Streptococcus pyogenes MGAS6180]; iron-sulfur cluster assembly ABC transporter ATP-binding protein SufC complement(1755448..1756218) Streptococcus equi subsp. zooepidemicus MGCS10565 6762123 YP_002124048.1 CDS rgpG NC_011134.1 1756339 1757499 R similar to ref|YP_601731.1| UDP-phosphate alpha-N-acetylglucosaminephosphotransferase [Streptococcus pyogenes MGAS10750]; Catalyzes the formation of UDP-PP-N- acetylglucosamine. Involved in the synthesis of anionic cell-wall polymers as it mediates the initiation of the linkage unit formation that appears to be common to the two types of teichoic acids attached to the peptidoglycan of B.subtilis; may also be involved in teichuronic acid biosynthesis ().; UDP-phosphate N-acetylglucosaminyl 1-phosphate transferase RgpG complement(1756339..1757499) Streptococcus equi subsp. zooepidemicus MGCS10565 6762120 YP_002124049.1 CDS mecA NC_011134.1 1757503 1758267 R enables recognition and targeting of proteins for proteolysis, involved in negative regulation of competence; adaptor protein complement(1757503..1758267) Streptococcus equi subsp. zooepidemicus MGCS10565 6762116 YP_002124050.1 CDS uppP NC_011134.1 1758387 1759226 R BacA; phosphatase activity in Escherichia coli not kinase; involved in bacitracin resistance as bacitracin supposedly sequesters UDP disphosphate which reduces the pool of lipid carrier available to the cell; UDP pyrophosphate phosphatase complement(1758387..1759226) Streptococcus equi subsp. zooepidemicus MGCS10565 6762090 YP_002124051.1 CDS Sez_1709 NC_011134.1 1759238 1759363 R hypothetical protein complement(1759238..1759363) Streptococcus equi subsp. zooepidemicus MGCS10565 6762109 YP_002124052.1 CDS Sez_1710 NC_011134.1 1759541 1761109 D similar to ref|NP_606545.1| glutamine-binding periplasmic protein [Streptococcus pyogenes MGAS8232]; Component of high-affinity glutamine permease, a binding-protein-dependent transport system.; amino acid ABC transporter, glutamine-binding protein/permease 1759541..1761109 Streptococcus equi subsp. zooepidemicus MGCS10565 6762098 YP_002124053.1 CDS Sez_1711 NC_011134.1 1761102 1761842 D similar to ref|YP_059585.1| Amino acid transport ATP-binding protein [Streptococcus pyogenes MGAS10394]; Probably part of a binding-protein-dependent transport system for an amino acid. Probably responsible for energy coupling to the transport system.; amino acid transport ATP-binding protein 1761102..1761842 Streptococcus equi subsp. zooepidemicus MGCS10565 6762095 YP_002124054.1 CDS Sez_1712 NC_011134.1 1762798 1763763 R similar to ref|YP_603153.1| Membrane protease family [Streptococcus pyogenes MGAS10750]; stomatin/prohibitin-family membrane protease subunit complement(1762798..1763763) Streptococcus equi subsp. zooepidemicus MGCS10565 6762092 YP_002124055.1 CDS Sez_1713 NC_011134.1 1763777 1763929 D hypothetical protein 1763777..1763929 Streptococcus equi subsp. zooepidemicus MGCS10565 6762067 YP_002124056.1 CDS Sez_1714 NC_011134.1 1763951 1765615 R similar to ref|YP_599282.1| Dihydroxyacetone kinase family protein [Streptococcus pyogenes MGAS10270]; dihydroxyacetone kinase family protein complement(1763951..1765615) Streptococcus equi subsp. zooepidemicus MGCS10565 6762002 YP_002124057.1 CDS Sez_1715 NC_011134.1 1765615 1765980 R similar to ref|YP_599283.1| General stress protein, Gls24 family [Streptococcus pyogenes MGAS10270]; alkaline-shock protein complement(1765615..1765980) Streptococcus equi subsp. zooepidemicus MGCS10565 6762080 YP_002124058.1 CDS rpmB NC_011134.1 1766132 1766320 R required for 70S ribosome assembly; 50S ribosomal protein L28 complement(1766132..1766320) Streptococcus equi subsp. zooepidemicus MGCS10565 6762076 YP_002124059.1 CDS fba NC_011134.1 1767275 1768243 R catalyzes the formation of glycerone phosphate and glyceraldehyde 3-phosphate from fructose 1,6, bisphosphate; fructose-bisphosphate aldolase complement(1767275..1768243) Streptococcus equi subsp. zooepidemicus MGCS10565 6762057 YP_002124060.1 CDS Sez_1718 NC_011134.1 1768496 1769359 R similar to ref|YP_060935.1| Alpha/beta hydrolase [Streptococcus pyogenes MGAS10394]; alpha/beta hydrolase complement(1768496..1769359) Streptococcus equi subsp. zooepidemicus MGCS10565 6761094 YP_002124061.1 CDS Sez_1719 NC_011134.1 1769387 1769530 D hypothetical protein 1769387..1769530 Streptococcus equi subsp. zooepidemicus MGCS10565 6762065 YP_002124062.1 CDS pyrG NC_011134.1 1769789 1771393 R CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer; CTP synthetase complement(1769789..1771393) Streptococcus equi subsp. zooepidemicus MGCS10565 6762061 YP_002124063.1 CDS tig NC_011134.1 1772500 1773783 R Tig; RopA; peptidyl-prolyl cis/trans isomerase; promotes folding of newly synthesized proteins; binds ribosomal 50S subunit; forms a homodimer; trigger factor complement(1772500..1773783) Streptococcus equi subsp. zooepidemicus MGCS10565 6762038 YP_002124064.1 CDS amyE NC_011134.1 1774121 1775530 R similar to dbj|BAA24177.1| alpha-amylase precursor [Streptococcus bovis]; Endohydrolysis of 1,4-?-D-glucosidic linkages in polysaccharides containing three or more 1,4-?-linked D-glucose units.; alpha-amylase complement(1774121..1775530) Streptococcus equi subsp. zooepidemicus MGCS10565 6762036 YP_002124065.1 CDS Sez_1725 NC_011134.1 1776028 1776819 D similar to ref|YP_001127832.1| mechanosensitive ion channel protein [Streptococcus pyogenes str. Manfredo]; potassium efflux system / small-conductance mechanosensitive channel 1776028..1776819 Streptococcus equi subsp. zooepidemicus MGCS10565 6762051 YP_002124066.1 CDS Sez_1726 NC_011134.1 1776914 1777474 R similar to ref|NP_687139.1| conserved hypothetical protein TIGR01440 [Streptococcus agalactiae 2603V/R]; hypothetical protein complement(1776914..1777474) Streptococcus equi subsp. zooepidemicus MGCS10565 6762050 YP_002124067.1 CDS Sez_1727 NC_011134.1 1777487 1777960 R similar to ref|NP_720565.1| hypothetical protein SMU.86 [Streptococcus mutans UA159]; hypothetical protein complement(1777487..1777960) Streptococcus equi subsp. zooepidemicus MGCS10565 6761992 YP_002124068.1 CDS Sez_1728 NC_011134.1 1777966 1778715 R catalyzes the formation of 4-amino-2-methyl-5-diphosphomethylpyrimidine; phosphomethylpyrimidine kinase complement(1777966..1778715) Streptococcus equi subsp. zooepidemicus MGCS10565 6762019 YP_002124069.1 CDS truA NC_011134.1 1778705 1779454 R mediates pseudouridylation (positions 38, 39, 40) at the tRNA anticodon region which contributes to the structural stability; tRNA pseudouridine synthase A complement(1778705..1779454) Streptococcus equi subsp. zooepidemicus MGCS10565 6762029 YP_002124070.1 CDS Sez_1730 NC_011134.1 1779451 1779621 R hypothetical protein complement(1779451..1779621) Streptococcus equi subsp. zooepidemicus MGCS10565 6762012 YP_002124071.1 CDS Sez_1731 NC_011134.1 1779641 1781005 D catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP; lysine and threonine sensitive; aspartate kinase 1779641..1781005 Streptococcus equi subsp. zooepidemicus MGCS10565 6762027 YP_002124072.1 CDS Sez_1732 NC_011134.1 1781096 1781227 R hypothetical protein complement(1781096..1781227) Streptococcus equi subsp. zooepidemicus MGCS10565 6762020 YP_002124073.1 CDS comX NC_011134.1 1781484 1781963 R similar to ref|NP_801488.1| competence protein (ComX1) [Streptococcus pyogenes SSI-1]; competence-specific sigma factor ComX complement(1781484..1781963) Streptococcus equi subsp. zooepidemicus MGCS10565 6762005 YP_002124074.1 CDS Sez_1734 NC_011134.1 1782200 1782337 R hypothetical protein complement(1782200..1782337) Streptococcus equi subsp. zooepidemicus MGCS10565 6761108 YP_002124075.1 CDS Sez_1735 NC_011134.1 1788219 1790630 R similar to ref|YP_329930.1| streptococcal histidine triad family protein [Streptococcus agalactiae A909]; histidine triad protein complement(1788219..1790630) Streptococcus equi subsp. zooepidemicus MGCS10565 6761172 YP_002124076.1 CDS lraI NC_011134.1 1790645 1791586 R similar to ref|NP_608045.1| laminin adhesion [Streptococcus pyogenes MGAS8232]; Part of the ATP-driven transport system adcABC for zinc. Required for transformability.; zinc-binding lipoprotein LraI precursor, laminin-binding protein complement(1790645..1791586) Streptococcus equi subsp. zooepidemicus MGCS10565 6761989 YP_002124077.1 CDS Sez_1737 NC_011134.1 1791898 1793445 R similar to ref|NP_687786.1| cell wall surface anchor family protein [Streptococcus agalactiae 2603V/R]; cell wall surface anchor family protein complement(1791898..1793445) Streptococcus equi subsp. zooepidemicus MGCS10565 6762003 YP_002124078.1 CDS Sez_1738 NC_011134.1 1793985 1795115 D similar to ref|YP_596508.1| transposase [Streptococcus pyogenes MGAS9429]; transposase IS1548-like 1793985..1795115 Streptococcus equi subsp. zooepidemicus MGCS10565 6761998 YP_002124079.1 CDS Sez_1739 NC_011134.1 1795343 1796224 R similar to ref|NP_816282.1| diacylglycerol kinase catalytic domain protein [Enterococcus faecalis V583]; Catalysis of the reaction: ATP + 1,2-diacylglycerol = ADP + 1,2-diacylglycerol 3-phosphate.; transcriptional regulator complement(1795343..1796224) Streptococcus equi subsp. zooepidemicus MGCS10565 6761994 YP_002124080.1 CDS galR NC_011134.1 1796389 1797390 R similar to pir||JC5310 galactose repressor - Streptococcus mutans; Repressor of the galactose operon. Binds galactose as an inducer.; HTH-type transcriptional regulator GalR complement(1796389..1797390) Streptococcus equi subsp. zooepidemicus MGCS10565 6761988 YP_002124081.1 CDS galK NC_011134.1 1797531 1798703 D catalyzes the formation of alpha-D-galactose 1-phosphate from D-galactose in galactose metabolism; galactokinase 1797531..1798703 Streptococcus equi subsp. zooepidemicus MGCS10565 6761970 YP_002124082.1 CDS galT NC_011134.1 1798707 1800191 D catalyzes the formation of alpha-D-glucose 1-phosphate and UDP-galactose from UDP-glucose and alpha-D-galactose 1-phosphate in galactose metabolism; galactose-1-phosphate uridylyltransferase 1798707..1800191 Streptococcus equi subsp. zooepidemicus MGCS10565 6761960 YP_002124083.1 CDS galE NC_011134.1 1800201 1801211 D similar to ref|NP_688912.1| UDP-glucose 4-epimerase [Streptococcus agalactiae 2603V/R]; Catalysis of the reaction: UDP-glucose = UDP-galactose.; UDP-glucose 4-epimerase GalE 1800201..1801211 Streptococcus equi subsp. zooepidemicus MGCS10565 6762221 YP_002124084.1 CDS galM NC_011134.1 1801288 1802331 D similar to gb|AAU21551.1| GalM [Streptococcus thermophilus]; Mutarotase converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose.; aldose 1-epimerase 1801288..1802331 Streptococcus equi subsp. zooepidemicus MGCS10565 6761871 YP_002124085.1 CDS rpsI NC_011134.1 1802829 1803221 R forms a direct contact with the tRNA during translation; 30S ribosomal protein S9 complement(1802829..1803221) Streptococcus equi subsp. zooepidemicus MGCS10565 6761866 YP_002124086.1 CDS rplM NC_011134.1 1803241 1803669 R in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit; 50S ribosomal protein L13 complement(1803241..1803669) Streptococcus equi subsp. zooepidemicus MGCS10565 6761862 YP_002124087.1 CDS Sez_1747 NC_011134.1 1803977 1804930 D similar to ref|YP_138591.1| IS1239 transposase [Streptococcus thermophilus LMG 18311]; transposase IS1239 1803977..1804930 Streptococcus equi subsp. zooepidemicus MGCS10565 6761848 YP_002124088.1 CDS Sez_1748 NC_011134.1 1804938 1805096 D hypothetical protein 1804938..1805096 Streptococcus equi subsp. zooepidemicus MGCS10565 6761737 YP_002124089.1 CDS Sez_1749 NC_011134.1 1805310 1806170 R similar to ref|YP_603238.1| Fatty acid-binding protein, DegV family [Streptococcus pyogenes MGAS10750]; DegV family protein complement(1805310..1806170) Streptococcus equi subsp. zooepidemicus MGCS10565 6761813 YP_002124090.1 CDS Sez_1750 NC_011134.1 1806355 1806873 R similar to ref|YP_001129143.1| hypothetical protein SpyM51624 [Streptococcus pyogenes str. Manfredo]; hypothetical protein complement(1806355..1806873) Streptococcus equi subsp. zooepidemicus MGCS10565 6761834 YP_002124091.1 CDS Sez_1751 NC_011134.1 1806874 1807620 R similar to ref|YP_281105.1| 23S rRNA methyltransferase [Streptococcus pyogenes MGAS6180]; tRNA/rRNA methyltransferase complement(1806874..1807620) Streptococcus equi subsp. zooepidemicus MGCS10565 6761830 YP_002124092.1 CDS Sez_1752 NC_011134.1 1807669 1808466 R similar to ref|YP_599330.1| hypothetical membrane associated protein [Streptococcus pyogenes MGAS10270]; hypothetical protein complement(1807669..1808466) Streptococcus equi subsp. zooepidemicus MGCS10565 6761828 YP_002124093.1 CDS Sez_1753 NC_011134.1 1808683 1809090 R similar to ref|ZP_00366252.1| COG1939: Uncharacterized protein conserved in bacteria [Streptococcus pyogenes M49 591]; similar to cysteinyl-tRNA synthetase; hypothetical protein complement(1808683..1809090) Streptococcus equi subsp. zooepidemicus MGCS10565 6761825 YP_002124094.1 CDS cysS NC_011134.1 1809083 1810429 R catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA; cysteinyl-tRNA synthetase complement(1809083..1810429) Streptococcus equi subsp. zooepidemicus MGCS10565 6761819 YP_002124095.1 CDS cysE NC_011134.1 1810548 1811084 R similar to ref|YP_599335.1| serineacetyltransferase [Streptococcus pyogenes MGAS10270]; Cysteine biosynthesis.; serine acetyltransferase CysE complement(1810548..1811084) Streptococcus equi subsp. zooepidemicus MGCS10565 6761795 YP_002124096.1 CDS Sez_1756 NC_011134.1 1811096 1811848 R similar to ref|YP_001129151.1| hypothetical protein SpyM51632 [Streptococcus pyogenes str. Manfredo]; hypothetical protein complement(1811096..1811848) Streptococcus equi subsp. zooepidemicus MGCS10565 6761789 YP_002124097.1 CDS pnpA NC_011134.1 1811841 1813985 R similar to ref|YP_281113.1| polynucleotide phosphorylase/polyadenylase [Streptococcus pyogenes MGAS6180]; Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction. Necessary for competence development in Bacillus subtilis. May be necessary for modification of the srfA transcript (stabilization or translation activation).; polynucleotide phosphorylase complement(1811841..1813985) Streptococcus equi subsp. zooepidemicus MGCS10565 6761785 YP_002124098.1 CDS rpsO NC_011134.1 1814354 1814623 R primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence; 30S ribosomal protein S15 complement(1814354..1814623) Streptococcus equi subsp. zooepidemicus MGCS10565 6761716 YP_002124099.1 CDS fnz2 NC_011134.1 1814889 1816337 R similar to dbj|BAD00708.1| fibronectin-binding protein [Streptococcus equi subsp. zooepidemicus]; The ability of bacteria to bind fibronectin has been proposed as a virulence factor enabling bacteria to colonize wound tissues and blood clots. Binding of plasma fibronectin to the bacterial surface might block adhesion receptors on S.aureus, thus representing an important defense mechanism against tissue invasion.; fibronectin-binding protein precursor Fnz2 complement(1814889..1816337) Streptococcus equi subsp. zooepidemicus MGCS10565 6761776 YP_002124100.1 CDS def NC_011134.1 1816708 1817322 D cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+); peptide deformylase 1816708..1817322 Streptococcus equi subsp. zooepidemicus MGCS10565 6761771 YP_002124101.1 CDS Sez_1761 NC_011134.1 1817449 1818030 R similar to ref|YP_283033.1| oxidoreductase [Streptococcus pyogenes MGAS5005]; hypothetical protein complement(1817449..1818030) Streptococcus equi subsp. zooepidemicus MGCS10565 6761793 YP_002124102.1 CDS Sez_1762 NC_011134.1 1818124 1818552 R similar to ref|YP_060997.1| Transcriptional regulator, MarR family [Streptococcus pyogenes MGAS10394]; Transcriptional Regulation; MarR family transcriptional regulator complement(1818124..1818552) Streptococcus equi subsp. zooepidemicus MGCS10565 6761761 YP_002124103.1 CDS polC NC_011134.1 1818674 1823071 R catalyzes DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time; required for leading strand synthesis; PolC exhibits 3' to 5' exonuclease activity; DNA polymerase III PolC complement(1818674..1823071) Streptococcus equi subsp. zooepidemicus MGCS10565 6761759 YP_002124104.1 CDS Sez_1764 NC_011134.1 1823406 1823963 R similar to ref|NP_720759.1| hypothetical protein SMU.301 [Streptococcus mutans UA159]; hypothetical protein complement(1823406..1823963) Streptococcus equi subsp. zooepidemicus MGCS10565 6761758 YP_002124105.1 CDS proS NC_011134.1 1824015 1825856 R catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro); prolyl-tRNA synthetase complement(1824015..1825856) Streptococcus equi subsp. zooepidemicus MGCS10565 6761769 YP_002124106.1 CDS Sez_1766 NC_011134.1 1826141 1827406 R similar to ref|YP_281127.1| pheromone-processing membrane metalloprotease [Streptococcus pyogenes MGAS6180]; zinc metalloprotease complement(1826141..1827406) Streptococcus equi subsp. zooepidemicus MGCS10565 6761768 YP_002124107.1 CDS cdsA NC_011134.1 1827438 1828232 R similar to ref|ZP_00365468.1| COG0575: CDP-diglyceride synthetase [Streptococcus pyogenes M49 591]; Catalysis of the reaction: CTP + phosphatidate = diphosphate + CDP-diacylglycerol.; phosphatidate cytidylyltransferase complement(1827438..1828232) Streptococcus equi subsp. zooepidemicus MGCS10565 6761753 YP_002124108.1 CDS uppS NC_011134.1 1828242 1828991 R catalyzes the formation of UDP pyrophosphate from isopentenyl pyrophosphate; UDP pyrophosphate synthase complement(1828242..1828991) Streptococcus equi subsp. zooepidemicus MGCS10565 6761762 YP_002124109.1 CDS yajC NC_011134.1 1829165 1829524 R member of preprotein translocase; forms a heterotrimer with SecD and SecF; links the SecD/SecF/YajC/YidC complex with the SecY/SecE/SecG complex; preprotein translocase subunit YajC complement(1829165..1829524) Streptococcus equi subsp. zooepidemicus MGCS10565 6761731 YP_002124110.1 CDS Sez_1770 NC_011134.1 1829638 1830000 R similar to ref|YP_061004.1| Thioredoxin [Streptococcus pyogenes MGAS10394]; transport accessory protein complement(1829638..1830000) Streptococcus equi subsp. zooepidemicus MGCS10565 6761744 YP_002124111.1 CDS dexB NC_011134.1 1830109 1831731 R similar to ref|YP_283044.1| glucan 1,6-alpha-glucosidase [Streptococcus pyogenes MGAS5005]; The physiological substrates may be short isomaltosaccharides.; glucan 1,6-alpha-glucosidase complement(1830109..1831731) Streptococcus equi subsp. zooepidemicus MGCS10565 6761713 YP_002124112.1 CDS Sez_1772 NC_011134.1 1831912 1833045 R similar to ref|NP_269942.1| multiple sugar-binding ABC transport system (ATP-binding protein) [Streptococcus pyogenes M1 GAS]; Involved in a binding protein-dependent transport system responsible for the uptake of melibiose, raffinose and isomaltotriose. Probably responsible for energy coupling to the transport system.; multiple sugar-binding transport ATP-binding protein complement(1831912..1833045) Streptococcus equi subsp. zooepidemicus MGCS10565 6761740 YP_002124113.1 CDS lrp NC_011134.1 1833196 1834044 R similar to emb|CAA51350.1| leucine rich protein [Streptococcus dysgalactiae subsp. equisimilis]; hypothetical protein complement(1833196..1834044) Streptococcus equi subsp. zooepidemicus MGCS10565 6761734 YP_002124114.1 CDS Sez_1774 NC_011134.1 1834339 1834515 R hypothetical protein complement(1834339..1834515) Streptococcus equi subsp. zooepidemicus MGCS10565 6761708 YP_002124115.1 CDS skc NC_011134.1 1834799 1836073 D similar to gb|AAC83933.1| streptokinase precursor [Streptococcus dysgalactiae subsp. equisimilis]; streptokinase plasminogen activator Skc 1834799..1836073 Streptococcus equi subsp. zooepidemicus MGCS10565 6761709 YP_002124116.1 CDS dtd NC_011134.1 1836198 1836641 R hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr); possible defense mechanism against a harmful effect of D-tyrosine; D-tyrosyl-tRNA(Tyr) deacylase complement(1836198..1836641) Streptococcus equi subsp. zooepidemicus MGCS10565 6761706 YP_002124117.1 CDS relA NC_011134.1 1836656 1838875 R similar to ref|NP_608020.1| (p)ppGpp synthetase [Streptococcus pyogenes MGAS8232]; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. This enzyme catalyzes the formation of pppGpp which is then hydrolyzed to form ppGpp.; GTP pyrophosphokinase complement(1836656..1838875) Streptococcus equi subsp. zooepidemicus MGCS10565 6761699 YP_002124118.1 CDS spaZ NC_011134.1 1839093 1840310 R similar to gb|AAD42939.2|AF086813_1 protective antigen [Streptococcus pyogenes]; protective antigen SpaZ complement(1839093..1840310) Streptococcus equi subsp. zooepidemicus MGCS10565 6761692 YP_002124119.1 CDS Sez_1779 NC_011134.1 1840558 1841742 D similar to ref|NP_608022.1| transcriptional regulator [Streptococcus pyogenes MGAS8232]; AraC family transcriptional regulator 1840558..1841742 Streptococcus equi subsp. zooepidemicus MGCS10565 6761669 YP_002124120.1 CDS nrdI NC_011134.1 1841951 1842409 D has a stimulatory effect on the ribonucleotide reductase activity of NrdH with NrdEF; flavoprotein NrdI 1841951..1842409 Streptococcus equi subsp. zooepidemicus MGCS10565 6761663 YP_002124121.1 CDS Sez_1781 NC_011134.1 1842590 1842736 R hypothetical protein complement(1842590..1842736) Streptococcus equi subsp. zooepidemicus MGCS10565 6761685 YP_002124122.1 CDS Sez_1782 NC_011134.1 1842714 1843535 R similar to ref|NP_608024.1| hypothetical protein spyM18_2049 [Streptococcus pyogenes MGAS8232]; Catalysis of the degradation of double-stranded DNA. It acts progressively in a 3' to 5' direction, releasing 5'-phosphomononucleotides.; exodeoxyribonuclease III complement(1842714..1843535) Streptococcus equi subsp. zooepidemicus MGCS10565 6761676 YP_002124123.1 CDS Sez_1783 NC_011134.1 1843613 1845799 R similar to ref|YP_603278.1| PTS system, glucose-specific IIABC component [Streptococcus pyogenes MGAS10750]; The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active-transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. This system is involved in glucose transport.; PTS system glucose-specific transporter subunit IICBA complement(1843613..1845799) Streptococcus equi subsp. zooepidemicus MGCS10565 6761648 YP_002124124.1 CDS Sez_1784 NC_011134.1 1846097 1847119 R similar to ref|NP_784004.1| transcription regulator [Lactobacillus plantarum WCFS1]; HTH-type transcriptional regulator MalR-like complement(1846097..1847119) Streptococcus equi subsp. zooepidemicus MGCS10565 6761665 YP_002124125.1 CDS Sez_1785 NC_011134.1 1847222 1848259 R similar to ref|YP_001200768.1| Predicted transcriptional regulator [Streptococcus suis 98HAH33]; hypothetical protein complement(1847222..1848259) Streptococcus equi subsp. zooepidemicus MGCS10565 6761661 YP_002124126.1 CDS Sez_1786 NC_011134.1 1848279 1849448 R similar to ref|YP_001198563.1| lantibiotic efflux protein [Streptococcus suis 05ZYH33]; hypothetical protein complement(1848279..1849448) Streptococcus equi subsp. zooepidemicus MGCS10565 6761639 YP_002124127.1 CDS Sez_1787 NC_011134.1 1849623 1849760 R hypothetical protein complement(1849623..1849760) Streptococcus equi subsp. zooepidemicus MGCS10565 6761649 YP_002124128.1 CDS Sez_1788 NC_011134.1 1849868 1850614 R in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA; cells lacking this function can grow, but are outcompeted by wild-type; SAM-dependent m(3)U1498 methyltransferase; 16S ribosomal RNA methyltransferase RsmE complement(1849868..1850614) Streptococcus equi subsp. zooepidemicus MGCS10565 6761647 YP_002124129.1 CDS prmA NC_011134.1 1850614 1851567 R methylates ribosomal protein L11 at multiple amino acid positions; mutations of these genes in Escherichia coli or Thermus thermophilus has no apparent phenotype; 50S ribosomal protein L11 methyltransferase complement(1850614..1851567) Streptococcus equi subsp. zooepidemicus MGCS10565 6761643 YP_002124130.1 CDS Sez_1790 NC_011134.1 1852127 1854670 D similar to ref|ZP_00874737.1| Streptococcal histidine triad [Streptococcus suis 89/1591]; internalin A-like histidine triad lipoprotein 1852127..1854670 Streptococcus equi subsp. zooepidemicus MGCS10565 6761638 YP_002124131.1 CDS Sez_1791 NC_011134.1 1854868 1855296 R similar to ref|ZP_01817507.1| MutT/nudix family protein [Streptococcus pneumoniae SP3-BS71]; MutT/nudix family protein complement(1854868..1855296) Streptococcus equi subsp. zooepidemicus MGCS10565 6761637 YP_002124132.1 CDS Sez_1792 NC_011134.1 1855316 1855657 R similar to ref|ZP_00366058.1| COG4043: Uncharacterized conserved protein [Streptococcus pyogenes M49 591]; hypothetical protein complement(1855316..1855657) Streptococcus equi subsp. zooepidemicus MGCS10565 6761612 YP_002124133.1 CDS Sez_1793 NC_011134.1 1855659 1856129 R similar to ref|YP_001129182.1| hypothetical protein SpyM51665 [Streptococcus pyogenes str. Manfredo]; hypothetical protein complement(1855659..1856129) Streptococcus equi subsp. zooepidemicus MGCS10565 6761634 YP_002124134.1 CDS pabA NC_011134.1 1856283 1858019 D similar to ref|YP_061021.1| 4-amino-4-deoxychorismate lyase [Streptococcus pyogenes MGAS10394]; Catalyzes the biosynthesis of 4-amino-4-deoxychorismate (ADC) from chorismate and glutamine.; para-aminobenzoate synthase PabA 1856283..1858019 Streptococcus equi subsp. zooepidemicus MGCS10565 6761604 YP_002124135.1 CDS pabB NC_011134.1 1858048 1858668 D TrpG; with TrpE catalyzes the formation of anthranilate and glutamate from chorismate and glutamine; TrpG provides the glutamine amidotransferase activity; anthranilate synthase component II 1858048..1858668 Streptococcus equi subsp. zooepidemicus MGCS10565 6761629 YP_002124136.1 CDS rarA NC_011134.1 1858661 1859932 D similar to ref|YP_061023.1| recombination factor protein RarA [Streptococcus pyogenes MGAS10394]; ATPase related to the helicase subunit of the Holliday junction resolvase [DNA replication, recombination, and repair]; COG2256.; recombination factor protein RarA 1858661..1859932 Streptococcus equi subsp. zooepidemicus MGCS10565 6761626 YP_002124137.1 CDS Sez_1797 NC_011134.1 1860513 1861082 D hypothetical protein 1860513..1861082 Streptococcus equi subsp. zooepidemicus MGCS10565 6761142 YP_002124138.1 CDS Sez_1798 NC_011134.1 1861193 1862053 D similar to ref|ZP_01825592.1| transcriptional activator, Rgg/GadR/MutR family protein, C-terminal domain [Streptococcus pneumoniae SP11-BS70]; Transcriptional regulator; positive transcriptional regulator MutR family 1861193..1862053 Streptococcus equi subsp. zooepidemicus MGCS10565 6762215 YP_002124139.1 CDS Sez_1799 NC_011134.1 1862313 1862534 D hypothetical protein 1862313..1862534 Streptococcus equi subsp. zooepidemicus MGCS10565 6762211 YP_002124140.1 CDS Sez_1800 NC_011134.1 1862515 1863411 D similar to ref|YP_820672.1| Permease of the major facilitator superfamily [Streptococcus thermophilus LMD-9]; permease 1862515..1863411 Streptococcus equi subsp. zooepidemicus MGCS10565 6762186 YP_002124141.1 CDS Sez_1801 NC_011134.1 1864067 1864582 D similar to ref|YP_281151.1| topology modulation protein [Streptococcus pyogenes MGAS6180]; topology modulation protein 1864067..1864582 Streptococcus equi subsp. zooepidemicus MGCS10565 6762208 YP_002124142.1 CDS cspZ.1 NC_011134.1 1866077 1867450 D similar to ref|YP_329518.1| cell wall surface anchor family protein [Streptococcus agalactiae A909]; Has domains with similarity to different streptococal surface proteins such as M protein, internalin, and histidine triad proteins.; Emm-like cell surface protein CspZ.1 1866077..1867450 Streptococcus equi subsp. zooepidemicus MGCS10565 6762182 YP_002124143.1 CDS sclZ.12 NC_011134.1 1867686 1868765 R similar to gb|AAQ91578.1| collagen-like protein 3 [Streptococcus equi]; Possible adhesin, has a collagen-structural-motif domain composed of 60 Gly-Xaa-Yaa repeats.; hypothetical protein complement(1867686..1868765) Streptococcus equi subsp. zooepidemicus MGCS10565 6761811 YP_002124144.1 CDS Sez_1804 NC_011134.1 1868964 1869533 R similar to ref|YP_001037859.1| Phosphoglycerate mutase [Clostridium thermocellum ATCC 27405]; phosphoglycerate mutase family protein complement(1868964..1869533) Streptococcus equi subsp. zooepidemicus MGCS10565 6761864 YP_002124145.1 CDS Sez_1805 NC_011134.1 1869535 1870617 R similar to ref|YP_815692.1| MccC family protein [Streptococcus pneumoniae D39]; microcin self-immunity protein complement(1869535..1870617) Streptococcus equi subsp. zooepidemicus MGCS10565 6761858 YP_002124146.1 CDS gldA NC_011134.1 1871123 1872214 R forms dimers and octamers; involved in conversion of glycerol to dihydroxy-acetone; glycerol dehydrogenase complement(1871123..1872214) Streptococcus equi subsp. zooepidemicus MGCS10565 6761841 YP_002124147.1 CDS fsa NC_011134.1 1872339 1873007 R similar to transaldolase from Escherichia coli; many organisms have multiple copies; fructose-6-phosphate aldolase complement(1872339..1873007) Streptococcus equi subsp. zooepidemicus MGCS10565 6761837 YP_002124148.1 CDS Sez_1808 NC_011134.1 1873022 1875439 R similar to ref|YP_281195.1| formate acetyltransferase [Streptococcus pyogenes MGAS6180]; Catalysis of the reaction: acetyl-CoA + formate = CoA + pyruvate.; pyruvate formate-lyase complement(1873022..1875439) Streptococcus equi subsp. zooepidemicus MGCS10565 6761836 YP_002124149.1 CDS celC NC_011134.1 1875720 1877024 R similar to ref|YP_603332.1| PTS system, cellobiose-specific IIC component [Streptococcus pyogenes MGAS10750]; The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. This system is involved in cellobiose transport.; cellobiose permease IIC component CelC complement(1875720..1877024) Streptococcus equi subsp. zooepidemicus MGCS10565 6761812 YP_002124150.1 CDS celB NC_011134.1 1877035 1877343 R similar to ref|YP_603333.1| PTS system, cellobiose-specific IIB component [Streptococcus pyogenes MGAS10750]; The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. This system is involved in cellobiose transport.; cellobiose-specific phosphotransferase enzyme IIB component CelB complement(1877035..1877343) Streptococcus equi subsp. zooepidemicus MGCS10565 6761829 YP_002124151.1 CDS celA NC_011134.1 1877368 1877688 R similar to ref|YP_283109.1| PTS system, cellobiose-specific IIA component [Streptococcus pyogenes MGAS5005]; The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. This system is involved in cellobiose transport.; PTS system cellobiose-specific transporter subunit IIA CelA complement(1877368..1877688) Streptococcus equi subsp. zooepidemicus MGCS10565 6761827 YP_002124152.1 CDS Sez_1812 NC_011134.1 1877722 1877847 R hypothetical protein complement(1877722..1877847) Streptococcus equi subsp. zooepidemicus MGCS10565 6761824 YP_002124153.1 CDS Sez_1813 NC_011134.1 1877927 1878907 R similar to ref|NP_269997.1| transcriptional regulator [Streptococcus pyogenes M1 GAS]; transcriptional regulator complement(1877927..1878907) Streptococcus equi subsp. zooepidemicus MGCS10565 6761816 YP_002124154.1 CDS Sez_1814 NC_011134.1 1878922 1879668 R similar to ref|ZP_00365881.1| COG1349: Transcriptional regulators of sugar metabolism [Streptococcus pyogenes M49 591]; HTH-type transcriptional regulator complement(1878922..1879668) Streptococcus equi subsp. zooepidemicus MGCS10565 6761807 YP_002124155.1 CDS Sez_1815 NC_011134.1 1879697 1880566 D similar to ref|NP_608074.1| pyruvate formate-lyase activating enzyme [Streptococcus pyogenes MGAS8232]; Activation of pyruvate formate-lyase 2 under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.; pyruvate formate-lyase activating enzyme 1879697..1880566 Streptococcus equi subsp. zooepidemicus MGCS10565 6761800 YP_002124156.1 CDS purA NC_011134.1 1880679 1881995 R catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis; adenylosuccinate synthetase complement(1880679..1881995) Streptococcus equi subsp. zooepidemicus MGCS10565 6761802 YP_002124157.1 CDS Sez_1817 NC_011134.1 1882028 1882213 D hypothetical protein 1882028..1882213 Streptococcus equi subsp. zooepidemicus MGCS10565 6761780 YP_002124158.1 CDS Sez_1818 NC_011134.1 1882314 1883171 D similar to ref|NP_606463.1| hypothetical protein spyM18_0155 [Streptococcus pyogenes MGAS8232]; hypothetical protein 1882314..1883171 Streptococcus equi subsp. zooepidemicus MGCS10565 6761796 YP_002124159.1 CDS Sez_1819 NC_011134.1 1883186 1884451 D similar to ref|NP_606462.1| toxic anion resistance protein [Streptococcus pyogenes MGAS8232]; toxic anion resistance protein 1883186..1884451 Streptococcus equi subsp. zooepidemicus MGCS10565 6761770 YP_002124160.1 CDS srtC.2 NC_011134.1 1884627 1885475 R similar to ref|YP_279575.1| sortase [Streptococcus pyogenes MGAS6180]; Fimbrial associated sortase required for subunit polymerization.; sortase complement(1884627..1885475) Streptococcus equi subsp. zooepidemicus MGCS10565 6761792 YP_002124161.1 CDS fszC NC_011134.1 1885553 1887202 R similar to gb|AAZ82124.1| fimbrial structural subunit [Streptococcus pyogenes serotype M23]; Fimbrial structural subunit involved in adhesion.; T-antigen-like fimbrial structural subunit protein FszC complement(1885553..1887202) Streptococcus equi subsp. zooepidemicus MGCS10565 6761784 YP_002124162.1 CDS fszD NC_011134.1 1887239 1890142 R similar to ref|YP_059477.1| Collagen adhesion protein [Streptococcus pyogenes MGAS10394]; Fimbrial component, has a centrally located Von Willebrand factor A domain and a carboxy end located Cna protein B-type domain.; fimbrial structural subunit protein FszD complement(1887239..1890142) Streptococcus equi subsp. zooepidemicus MGCS10565 6761778 YP_002124163.1 CDS Sez_1823 NC_011134.1 1890417 1891919 D similar to ref|ZP_00782298.1| transcription regulator, , [Streptococcus agalactiae H36B]; Regulation of fimbrial gene transcription.; RofA/Nra-like transcriptional regulator 1890417..1891919 Streptococcus equi subsp. zooepidemicus MGCS10565 6761735 YP_002124164.1 CDS Sez_1824 NC_011134.1 1891943 1892074 R hypothetical protein complement(1891943..1892074) Streptococcus equi subsp. zooepidemicus MGCS10565 6761756 YP_002124165.1 CDS fbpZ NC_011134.1 1892313 1894811 R similar to ref|YP_597726.1| Fibronectin-binding protein [Streptococcus pyogenes MGAS10270]; fibronectin-binding protein FbpZ complement(1892313..1894811) Streptococcus equi subsp. zooepidemicus MGCS10565 6761766 YP_002124166.1 CDS srtC.3 NC_011134.1 1894872 1895696 R similar to ref|YP_597725.1| Sortase [Streptococcus pyogenes MGAS10270]; Fimbrial associated dedicated sortase required for subunit polymerization.; sortase complement(1894872..1895696) Streptococcus equi subsp. zooepidemicus MGCS10565 6761746 YP_002124167.1 CDS srtC.4 NC_011134.1 1895711 1896541 R similar to ref|YP_597720.1| Sortase [Streptococcus pyogenes MGAS10270]; Fimbrial associated dedicated sortase required for subunit polymerization.; sortase complement(1895711..1896541) Streptococcus equi subsp. zooepidemicus MGCS10565 6761736 YP_002124168.1 CDS fszE NC_011134.1 1896591 1897505 R similar to ref|YP_597719.1| hypothetical protein MGAS10270_Spy0110 [Streptococcus pyogenes MGAS10270]; Fimbrial subunit protein, has a Cna B-type domain.; T-antigen-like fimbrial structural subunit protein FszE complement(1896591..1897505) Streptococcus equi subsp. zooepidemicus MGCS10565 6761727 YP_002124169.1 CDS fszF NC_011134.1 1897630 1899480 R similar to ref|YP_597718.1| hypothetical protein MGAS10270_Spy0109 [Streptococcus pyogenes MGAS10270]; Fimbrial structural subunit protein.; fimbrial subunit protein FszF complement(1897630..1899480) Streptococcus equi subsp. zooepidemicus MGCS10565 6761714 YP_002124170.1 CDS Sez_1830 NC_011134.1 1899760 1901022 D similar to ref|ZP_00784533.1| transcriptional regulator, AraC family [Streptococcus agalactiae COH1]; AraC family transcriptional regulator 1899760..1901022 Streptococcus equi subsp. zooepidemicus MGCS10565 6761739 YP_002124171.1 CDS Sez_1831 NC_011134.1 1901106 1901240 R hypothetical protein complement(1901106..1901240) Streptococcus equi subsp. zooepidemicus MGCS10565 6761711 YP_002124172.1 CDS hslO NC_011134.1 1901272 1902144 D becomes active under oxidative stress; four conserved cysteines bind a zinc atom when they are in the reduced state and the enzyme is inactive; oxidative stress results in oxidized cysteines, release of zinc, and binding of Hsp33 to aggregation-prone proteins; forms dimers and higher order oligomers; heat shock protein 33 1901272..1902144 Streptococcus equi subsp. zooepidemicus MGCS10565 6761730 YP_002124173.1 CDS dus NC_011134.1 1902167 1903108 D similar to ref|YP_595837.1| tRNA-dihydrouridine synthase [Streptococcus pyogenes MGAS9429]; Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs.; tRNA-dihydrouridine synthase Dus 1902167..1903108 Streptococcus equi subsp. zooepidemicus MGCS10565 6761726 YP_002124174.1 CDS Sez_1834 NC_011134.1 1903129 1903770 D similar to dbj|BAB16044.1| similar to Lactobacillus acidophilus dA/dG-kinase [Streptococcus equi subsp. zooepidemicus]; DGK/DAK plays an essential role in generating the deoxyribonucleotide precursors, dGTP and dATP, for DNA metabolism.; deoxyguanosine kinase 1903129..1903770 Streptococcus equi subsp. zooepidemicus MGCS10565 6761707 YP_002124175.1 CDS Sez_1835 NC_011134.1 1904052 1905056 D similar to ref|NP_687848.1| hypothetical protein SAG0833 [Streptococcus agalactiae 2603V/R]; hypothetical protein 1904052..1905056 Streptococcus equi subsp. zooepidemicus MGCS10565 6761691 YP_002124176.1 CDS Sez_1836 NC_011134.1 1905107 1905910 R similar to ref|YP_001198619.1| ABC-type uncharacterized transport system, ATPase component [Streptococcus suis 05ZYH33]; Part of the ABC transporter complex. Responsible for energy coupling to the transport system.; ABC transporter ATP-binding protein complement(1905107..1905910) Streptococcus equi subsp. zooepidemicus MGCS10565 6761673 YP_002124177.1 CDS Sez_1837 NC_011134.1 1905919 1906803 R similar to ref|YP_001200827.1| ABC-type uncharacterized transport system, permease component [Streptococcus suis 98HAH33]; Part of the binding-protein-dependent transport system. Probably responsible for the translocation of the substrate across the membrane.; ABC transporter permease complement(1905919..1906803) Streptococcus equi subsp. zooepidemicus MGCS10565 6761580 YP_002124178.1 CDS Sez_1838 NC_011134.1 1906913 1907875 R similar to ref|YP_001200828.1| hypothetical protein SSU98_1270 [Streptococcus suis 98HAH33]; ABC transporter substrate-binding.; ABC transporter substrate-binding lipoprotein complement(1906913..1907875) Streptococcus equi subsp. zooepidemicus MGCS10565 6761666 YP_002124179.1 CDS Sez_1839 NC_011134.1 1907902 1908888 R similar to ref|YP_001200829.1| ABC transporter permease [Streptococcus suis 98HAH33]; substrate-binding for ABC transport system.; ABC transporter substrate-binding lipoprotein complement(1907902..1908888) Streptococcus equi subsp. zooepidemicus MGCS10565 6761662 YP_002124180.1 CDS Sez_1840 NC_011134.1 1909273 1910226 R similar to ref|YP_138591.1| IS1239 transposase [Streptococcus thermophilus LMG 18311]; transposase IS1239 complement(1909273..1910226) Streptococcus equi subsp. zooepidemicus MGCS10565 6761684 YP_002124181.1 CDS ssb NC_011134.1 1911977 1912372 R binds to single stranded DNA and may facilitate the binding and interaction of other proteins to DNA; single-stranded DNA-binding protein complement(1911977..1912372) Streptococcus equi subsp. zooepidemicus MGCS10565 6761644 YP_002124182.1 CDS Sez_1845 NC_011134.1 1912426 1913196 D similar to ref|ZP_00784652.1| conserved hypothetical protein [Streptococcus agalactiae COH1]; S-adenosylmethionine-dependent methyltransferase 1912426..1913196 Streptococcus equi subsp. zooepidemicus MGCS10565 6761664 YP_002124183.1 CDS Sez_1846 NC_011134.1 1913498 1914124 R similar to ref|YP_059468.1| tRNA binding domain protein [Streptococcus pyogenes MGAS10394]; tRNA binding domain-containing protein complement(1913498..1914124) Streptococcus equi subsp. zooepidemicus MGCS10565 6761659 YP_002124184.1 CDS trxA NC_011134.1 1914139 1914456 R similar to ref|YP_059467.1| Thioredoxin [Streptococcus pyogenes MGAS10394]; Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions.; thioredoxin complement(1914139..1914456) Streptococcus equi subsp. zooepidemicus MGCS10565 6761650 YP_002124185.1 CDS Sez_1848 NC_011134.1 1914453 1914800 R similar to ref|NP_801354.1| hypothetical protein SPs0092 [Streptococcus pyogenes SSI-1]; hypothetical protein complement(1914453..1914800) Streptococcus equi subsp. zooepidemicus MGCS10565 6761632 YP_002124186.1 CDS pepA NC_011134.1 1915141 1916208 D similar to ref|YP_595830.1| glutamyl aminopeptidase [Streptococcus pyogenes MGAS9429]; Release of N-terminal glutamate (and to a lesser extent aspartate) from a peptide.; glutamyl aminopeptidase PepA 1915141..1916208 Streptococcus equi subsp. zooepidemicus MGCS10565 6761646 YP_002124187.1 CDS proC NC_011134.1 1916292 1917065 D catalyzes the formation of L-proline from pyrroline-5-carboxylate; pyrroline-5-carboxylate reductase 1916292..1917065 Streptococcus equi subsp. zooepidemicus MGCS10565 6761640 YP_002124188.1 CDS Sez_1851 NC_011134.1 1917300 1917737 R similar to ref|NP_268507.1| hypothetical protein SPy_0110 [Streptococcus pyogenes M1 GAS]; hypothetical protein complement(1917300..1917737) Streptococcus equi subsp. zooepidemicus MGCS10565 6761618 YP_002124189.1 CDS Sez_1852 NC_011134.1 1917767 1918441 R similar to ref|YP_821152.1| Predicted metal-dependent membrane protease [Streptococcus thermophilus LMD-9]; membrane-bound protease CAAX family complement(1917767..1918441) Streptococcus equi subsp. zooepidemicus MGCS10565 6761615 YP_002124190.1 CDS Sez_1853 NC_011134.1 1918451 1918903 R similar to ref|NP_722275.1| hypothetical protein SMU.1976c [Streptococcus mutans UA159]; hypothetical protein complement(1918451..1918903) Streptococcus equi subsp. zooepidemicus MGCS10565 6761611 YP_002124191.1 CDS Sez_1854 NC_011134.1 1918905 1919108 R similar to ref|YP_001451172.1| HTH DNA-binding protein [Streptococcus gordonii str. Challis substr. CH1]; HTH-type transcriptional regulator complement(1918905..1919108) Streptococcus equi subsp. zooepidemicus MGCS10565 6761633 YP_002124192.1 CDS Sez_1855 NC_011134.1 1919539 1920270 D similar to ref|YP_597530.1| hypothetical protein MGAS9429_Spy1799 [Streptococcus pyogenes MGAS9429]; hypothetical protein 1919539..1920270 Streptococcus equi subsp. zooepidemicus MGCS10565 6761603 YP_002124193.1 CDS Sez_1856 NC_011134.1 1920254 1920397 R hypothetical protein complement(1920254..1920397) Streptococcus equi subsp. zooepidemicus MGCS10565 6761627 YP_002124194.1 CDS nrdG NC_011134.1 1920731 1921345 R similar to ref|YP_061106.1| Anaerobic ribonucleoside-triphosphate reductase activating protein [Streptococcus pyogenes MGAS10394]; Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.; anaerobic ribonucleoside-triphosphate reductase-activating protein NrdG complement(1920731..1921345) Streptococcus equi subsp. zooepidemicus MGCS10565 6761624 YP_002124195.1 CDS Sez_1858 NC_011134.1 1921355 1921849 R similar to ref|YP_815708.1| acetyltransferase, GNAT family protein [Streptococcus pneumoniae D39]; acetyltransferase GNAT Family complement(1921355..1921849) Streptococcus equi subsp. zooepidemicus MGCS10565 6761594 YP_002124196.1 CDS Sez_1859 NC_011134.1 1921862 1922797 R similar to ref|YP_281240.1| oxidoreductase [Streptococcus pyogenes MGAS6180]; oxidoreductase Mvi-like complement(1921862..1922797) Streptococcus equi subsp. zooepidemicus MGCS10565 6762283 YP_002124197.1 CDS Sez_1860 NC_011134.1 1922825 1922971 R similar to ref|NP_608112.1| hypothetical protein spyM18_2167 [Streptococcus pyogenes MGAS8232]; hypothetical protein complement(1922825..1922971) Streptococcus equi subsp. zooepidemicus MGCS10565 6761283 YP_002124198.1 CDS nrdD NC_011134.1 1923077 1925275 R Catalyzes the reduction of nucleoside 5'-triphosphates to 2'-deoxynucleoside 5'-triphosphates; anaerobic ribonucleoside triphosphate reductase complement(1923077..1925275) Streptococcus equi subsp. zooepidemicus MGCS10565 6761268 YP_002124199.1 CDS Sez_1862 NC_011134.1 1925371 1926906 R similar to ref|NP_665599.1| hypothetical protein SpyM3_1795 [Streptococcus pyogenes MGAS315]; hypothetical protein complement(1925371..1926906) Streptococcus equi subsp. zooepidemicus MGCS10565 6761346 YP_002124200.1 CDS Sez_1863 NC_011134.1 1927075 1927200 D hypothetical protein 1927075..1927200 Streptococcus equi subsp. zooepidemicus MGCS10565 6761344 YP_002124201.1 CDS Sez_1864 NC_011134.1 1927482 1927781 R similar to ref|NP_270036.1| hypothetical protein SPy_2112 [Streptococcus pyogenes M1 GAS]; hypothetical protein complement(1927482..1927781) Streptococcus equi subsp. zooepidemicus MGCS10565 6761298 YP_002124202.1 CDS Sez_1865 NC_011134.1 1927791 1928201 R similar to ref|YP_140369.1| Holliday junction resolvase-like protein [Streptococcus thermophilus LMG 18311]; Could be a nuclease that resolves Holliday junction intermediates in genetic recombination.; Holliday junction resolvase RvuC-like complement(1927791..1928201) Streptococcus equi subsp. zooepidemicus MGCS10565 6761342 YP_002124203.1 CDS Sez_1866 NC_011134.1 1928207 1928476 R similar to ref|ZP_00365335.1| COG4472: Uncharacterized protein conserved in bacteria [Streptococcus pyogenes M49 591]; hypothetical protein complement(1928207..1928476) Streptococcus equi subsp. zooepidemicus MGCS10565 6761343 YP_002124204.1 CDS spxA NC_011134.1 1928589 1928987 R the anti-alpha factor Spx interacts with RNA polymerase alpha subunit C-terminal domain in a region that interacts with the sigma 70 subunit and may interfere with activation of promoters; in Bacillus subtilis this protein is a substrate for ClpXP protease; blocks transcription of the competence regulatory gene encoded by the srf operon; regulates a number of genes involved in thiol homeostasis including trxA and trxB; monomeric member of ArsC family of proteins; does not bind DNA; contains a disulfide bond between C10 and C13 which may sense disulfide stress; transcriptional regulator Spx complement(1928589..1928987) Streptococcus equi subsp. zooepidemicus MGCS10565 6761341 YP_002124205.1 CDS Sez_1868 NC_011134.1 1929355 1929798 R similar to ref|YP_140248.1| ISSth1, transposase (orf2), IS3 family [Streptococcus thermophilus LMG 18311]; ISSth1 transposase orfC complement(1929355..1929798) Streptococcus equi subsp. zooepidemicus MGCS10565 6761317 YP_002124206.1 CDS Sez_1869 NC_011134.1 1929782 1930153 R similar to ref|YP_139290.1| ISSth1, transposase (orf2), IS3 family [Streptococcus thermophilus LMG 18311]; ISSth1 transposase orfB complement(1929782..1930153) Streptococcus equi subsp. zooepidemicus MGCS10565 6761316 YP_002124207.1 CDS Sez_1870 NC_011134.1 1930240 1930926 R similar to ref|YP_139291.1| ISSth1, transposase (orf1), IS3 family [Streptococcus thermophilus LMG 18311]; ISSth1 transposase orfA complement(1930240..1930926) Streptococcus equi subsp. zooepidemicus MGCS10565 6761315 YP_002124208.1 CDS Sez_1871 NC_011134.1 1931001 1931516 D similar to ref|YP_602677.1| Transposase [Streptococcus pyogenes MGAS10750]; transposase IS861 orfA 1931001..1931516 Streptococcus equi subsp. zooepidemicus MGCS10565 6761337 YP_002124209.1 CDS Sez_1872 NC_011134.1 1931540 1932343 D similar to ref|YP_596865.1| transposase [Streptococcus pyogenes MGAS9429]; transposase IS861 orfB 1931540..1932343 Streptococcus equi subsp. zooepidemicus MGCS10565 6761336 YP_002124210.1 CDS recA NC_011134.1 1932481 1933617 R catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs; recombinase A complement(1932481..1933617) Streptococcus equi subsp. zooepidemicus MGCS10565 6761278 YP_002124211.1 CDS cinA NC_011134.1 1933711 1934982 R similar to ref|YP_281249.1| competence damage-inducible protein A [Streptococcus pyogenes MGAS6180]; competence damage-inducible protein A complement(1933711..1934982) Streptococcus equi subsp. zooepidemicus MGCS10565 6761206 YP_002124212.1 CDS Sez_1875 NC_011134.1 1935668 1935958 R similar to ref|YP_280686.1| hypothetical protein M28_Spy1221 [Streptococcus pyogenes MGAS6180]; hypothetical protein complement(1935668..1935958) Streptococcus equi subsp. zooepidemicus MGCS10565 6761237 YP_002124213.1 CDS slaA NC_011134.1 1935952 1936524 R similar to ref|NP_665008.1| streptococcal phospholipase A2 - phage associated [Streptococcus pyogenes MGAS315]; Cleaves phospholipids at SN2 position.; phosphlipase A2 SlaA complement(1935952..1936524) Streptococcus equi subsp. zooepidemicus MGCS10565 6761251 YP_002124214.1 CDS Sez_1877 NC_011134.1 1936810 1937763 D similar to ref|YP_138591.1| IS1239 transposase [Streptococcus thermophilus LMG 18311]; transposase IS1239 1936810..1937763 Streptococcus equi subsp. zooepidemicus MGCS10565 6761231 YP_002124215.1 CDS Sez_1878 NC_011134.1 1937907 1938752 D similar to ref|YP_001036163.1| hypothetical protein SSA_2251 [Streptococcus sanguinis SK36]; hypothetical protein 1937907..1938752 Streptococcus equi subsp. zooepidemicus MGCS10565 6761254 YP_002124216.1 CDS guaA NC_011134.1 1939197 1939748 R similar to ref|YP_281250.1| DNA-3-methyladenine glycosylase [Streptococcus pyogenes MGAS6180]; Catalyzes the synthesis of GMP from XMP.; GMP synthase complement(1939197..1939748) Streptococcus equi subsp. zooepidemicus MGCS10565 6761219 YP_002124217.1 CDS ruvA NC_011134.1 1939758 1940354 R plays an essential role in ATP-dependent branch migration of the Holliday junction; Holliday junction DNA helicase RuvA complement(1939758..1940354) Streptococcus equi subsp. zooepidemicus MGCS10565 6761240 YP_002124218.1 CDS Sez_1881 NC_011134.1 1940356 1941531 R similar to ref|YP_597545.1| multidrug resistance protein [Streptococcus pyogenes MGAS9429]; major facilitator family transporter complement(1940356..1941531) Streptococcus equi subsp. zooepidemicus MGCS10565 6761217 YP_002124219.1 CDS mutL NC_011134.1 1941590 1943572 R This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. Promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex; DNA mismatch repair protein complement(1941590..1943572) Streptococcus equi subsp. zooepidemicus MGCS10565 6761235 YP_002124220.1 CDS mutS NC_011134.1 1943719 1946232 R This protein performs the mismatch recognition step during the DNA repair process; DNA mismatch repair protein MutS complement(1943719..1946232) Streptococcus equi subsp. zooepidemicus MGCS10565 6761234 YP_002124221.1 CDS Sez_1884 NC_011134.1 1946246 1946596 R similar to ref|NP_722381.1| hypothetical protein SMU.2092c [Streptococcus mutans UA159]; hypothetical protein complement(1946246..1946596) Streptococcus equi subsp. zooepidemicus MGCS10565 6761213 YP_002124222.1 CDS argR NC_011134.1 1946598 1947035 R similar to ref|YP_599508.1| Arginine repressor, argR [Streptococcus pyogenes MGAS10270]; Regulates arginine biosynthesis genes; arginine repressor ArgR complement(1946598..1947035) Streptococcus equi subsp. zooepidemicus MGCS10565 6761233 YP_002124223.1 CDS msrA NC_011134.1 1949058 1950452 R similar to ref|YP_001488305.1| ABC superfamily ATP binding cassette transporter, ABC protein [Bacillus pumilus SAFR-032]; Possibly confers resistance to 14-membered ring macrolides (like erythromycin) and to B streptogramins, by acting as an ATP-dependent efflux pump.; ABC transporter ATP-binding protein complement(1949058..1950452) Streptococcus equi subsp. zooepidemicus MGCS10565 6761247 YP_002124224.1 CDS Sez_1889 NC_011134.1 1950624 1951538 R similar to ref|YP_281284.1| hypothetical membrane spanning protein [Streptococcus pyogenes MGAS6180]; transporter complement(1950624..1951538) Streptococcus equi subsp. zooepidemicus MGCS10565 6761223 YP_002124225.1 CDS Sez_1890 NC_011134.1 1951682 1952563 R similar to ref|YP_597553.1| hypothetical membrane spanning protein [Streptococcus pyogenes MGAS9429]; hypothetical protein complement(1951682..1952563) Streptococcus equi subsp. zooepidemicus MGCS10565 6761244 YP_002124226.1 CDS Sez_1891 NC_011134.1 1952579 1953526 R similar to ref|ZP_00366175.1| COG1284: Uncharacterized conserved protein [Streptococcus pyogenes M49 591]; hypothetical protein complement(1952579..1953526) Streptococcus equi subsp. zooepidemicus MGCS10565 6761243 YP_002124227.1 CDS aspS NC_011134.1 1953519 1955267 R catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes; aspartyl-tRNA synthetase complement(1953519..1955267) Streptococcus equi subsp. zooepidemicus MGCS10565 6761211 YP_002124228.1 CDS hisS NC_011134.1 1955495 1956775 R catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG; histidyl-tRNA synthetase complement(1955495..1956775) Streptococcus equi subsp. zooepidemicus MGCS10565 6761230 YP_002124229.1 CDS rpmF NC_011134.1 1957184 1957366 D some L32 proteins have zinc finger motifs consisting of CXXC while others do not; 50S ribosomal protein L32 1957184..1957366 Streptococcus equi subsp. zooepidemicus MGCS10565 6761226 YP_002124230.1 CDS rpmG NC_011134.1 1957382 1957531 D in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif; 50S ribosomal protein L33 1957382..1957531 Streptococcus equi subsp. zooepidemicus MGCS10565 6761225 YP_002124231.1 CDS Sez_1896 NC_011134.1 1957699 1958991 R similar to ref|YP_139512.1| IS1193 transposase [Streptococcus thermophilus LMG 18311]; transposase IS1193D complement(1957699..1958991) Streptococcus equi subsp. zooepidemicus MGCS10565 6761208 YP_002124232.1 CDS plcR NC_011134.1 1959248 1960105 R similar to ref|NP_345531.1| transcriptional regulator PlcR, [Streptococcus pneumoniae TIGR4]; transcriptional regulator PlcR-like complement(1959248..1960105) Streptococcus equi subsp. zooepidemicus MGCS10565 6761222 YP_002124233.1 CDS Sez_1898 NC_011134.1 1960147 1961259 R similar to ref|YP_078429.1| Major facilitator superfamily [Bacillus licheniformis ATCC 14580]; major facilitator family protein complement(1960147..1961259) Streptococcus equi subsp. zooepidemicus MGCS10565 6761218 YP_002124234.1 CDS Sez_1899 NC_011134.1 1961324 1962334 R transporter complement(1961324..1962334) Streptococcus equi subsp. zooepidemicus MGCS10565 6761357 YP_002124235.1 CDS Sez_1900 NC_011134.1 1962324 1963388 R similar to ref|NP_815050.1| HesA/MoeB/ThiF family protein [Enterococcus faecalis V583]; HesA/MoeB/ThiF family protein complement(1962324..1963388) Streptococcus equi subsp. zooepidemicus MGCS10565 6761215 YP_002124236.1 CDS cspZ.2 NC_011134.1 1963854 1965734 D similar to gb|AAN18298.1| immunoreactive protein Se68.9 [Streptococcus equi]; Emm-like cell surface protein CspZ.2 1963854..1965734 Streptococcus equi subsp. zooepidemicus MGCS10565 6761286 YP_002124237.1 CDS Sez_1902 NC_011134.1 1965964 1967766 D similar to ref|NP_830667.1| Sensor protein comP [Bacillus cereus ATCC 14579]; TCS sensor kinase 1965964..1967766 Streptococcus equi subsp. zooepidemicus MGCS10565 6761356 YP_002124238.1 CDS Sez_1903 NC_011134.1 1967744 1968343 D similar to ref|YP_001196982.1| two component transcriptional regulator, LuxR family [Flavobacterium johnsoniae UW101]; TCS response regulator 1967744..1968343 Streptococcus equi subsp. zooepidemicus MGCS10565 6760357 YP_002124239.1 CDS Sez_1904 NC_011134.1 1968451 1969377 D similar to gb|AAC33119.1| avirulence D protein [Pseudomonas syringae pv. cilantro]; avirulence AvrD-like protein 1968451..1969377 Streptococcus equi subsp. zooepidemicus MGCS10565 6760523 YP_002124240.1 CDS Sez_1905 NC_011134.1 1969370 1970146 D similar to ref|YP_873838.1| hypothetical protein Acel_2080 [Acidothermus cellulolyticus 11B]; hypothetical protein 1969370..1970146 Streptococcus equi subsp. zooepidemicus MGCS10565 6760546 YP_002124241.1 CDS Sez_1906 NC_011134.1 1970155 1970826 D similar to ref|ZP_01940408.1| ABC transporter, ATP-binding protein [Listeria monocytogenes 10403S]; ABC transporter ATP-binding protein 1970155..1970826 Streptococcus equi subsp. zooepidemicus MGCS10565 6760538 YP_002124242.1 CDS Sez_1907 NC_011134.1 1970831 1973116 D similar to gb|AAN18297.1| ABC transporter permease [Streptococcus equi]; ABC transporter permease 1970831..1973116 Streptococcus equi subsp. zooepidemicus MGCS10565 6760723 YP_002124243.1 CDS Sez_1908 NC_011134.1 1973586 1974401 D hypothetical protein 1973586..1974401 Streptococcus equi subsp. zooepidemicus MGCS10565 6760533 YP_002124244.1 CDS Sez_1909 NC_011134.1 1974173 1974811 D similar to ref|XP_312188.4| AGAP002737-PA [Anopheles gambiae str. PEST]; hypothetical protein 1974173..1974811 Streptococcus equi subsp. zooepidemicus MGCS10565 6760413 YP_002124245.1 CDS Sez_1911 NC_011134.1 1975927 1976769 D similar to ref|YP_599528.1| Integral membrane protein [Streptococcus pyogenes MGAS10270]; hypothetical protein 1975927..1976769 Streptococcus equi subsp. zooepidemicus MGCS10565 6760860 YP_002124246.1 CDS Sez_1912 NC_011134.1 1976856 1977482 R similar to ref|YP_599529.1| Phosphohydrolase [Streptococcus pyogenes MGAS10270]; Probably mediates the hydrolysis of some nucleoside diphosphate derivatives.; phosphohydrolase MutT/nudix family protein complement(1976856..1977482) Streptococcus equi subsp. zooepidemicus MGCS10565 6760807 YP_002124247.1 CDS Sez_1913 NC_011134.1 1977684 1978010 D similar to ref|YP_061164.1| Transcriptional regulator, PadR family [Streptococcus pyogenes MGAS10394]; transcriptional regulator PadR family 1977684..1978010 Streptococcus equi subsp. zooepidemicus MGCS10565 6761354 YP_002124248.1 CDS Sez_1914 NC_011134.1 1977997 1978356 D hypothetical protein 1977997..1978356 Streptococcus equi subsp. zooepidemicus MGCS10565 6761347 YP_002124249.1 CDS Sez_1915 NC_011134.1 1978375 1979430 D similar to ref|YP_001449372.1| hypothetical protein SGO_0050 [Streptococcus gordonii str. Challis substr. CH1]; hypothetical protein 1978375..1979430 Streptococcus equi subsp. zooepidemicus MGCS10565 6761335 YP_002124250.1 CDS Sez_1916 NC_011134.1 1979533 1981812 R similar to ref|NP_608148.1| hypothetical protein spyM18_2213 [Streptococcus pyogenes MGAS8232]; hypothetical protein complement(1979533..1981812) Streptococcus equi subsp. zooepidemicus MGCS10565 6761310 YP_002124251.1 CDS Sez_1917 NC_011134.1 1981875 1982477 D similar to ref|NP_270087.1| transcriptional regulator (TetR/AcrR family) [Streptococcus pyogenes M1 GAS]; TetR family transcriptional regulator 1981875..1982477 Streptococcus equi subsp. zooepidemicus MGCS10565 6761332 YP_002124252.1 CDS Sez_1918 NC_011134.1 1982916 1983263 R similar to ref|ZP_00787238.1| conserved hypothetical protein [Streptococcus agalactiae CJB111]; hypothetical protein complement(1982916..1983263) Streptococcus equi subsp. zooepidemicus MGCS10565 6761331 YP_002124253.1 CDS Sez_1919 NC_011134.1 1983253 1983540 R similar to ref|ZP_00787181.1| Unknown, [Streptococcus agalactiae CJB111]; hypothetical protein complement(1983253..1983540) Streptococcus equi subsp. zooepidemicus MGCS10565 6761305 YP_002124254.1 CDS Sez_1920 NC_011134.1 1983645 1983776 R similar to ref|YP_330669.1| prophage Sa05, transcriptional regulator, ArpU family [Streptococcus agalactiae A909]; transcriptional regulator phage associated ArpU family complement(1983645..1983776) Streptococcus equi subsp. zooepidemicus MGCS10565 6761325 YP_002124255.1 CDS Sez_1921 NC_011134.1 1984032 1984343 R similar to ref|YP_001129292.1| DNA-binding phage protein [Streptococcus pyogenes str. Manfredo]; phage associated protein complement(1984032..1984343) Streptococcus equi subsp. zooepidemicus MGCS10565 6761323 YP_002124256.1 CDS rpsD NC_011134.1 1984693 1985304 R primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination; 30S ribosomal protein S4 complement(1984693..1985304) Streptococcus equi subsp. zooepidemicus MGCS10565 6761318 YP_002124257.1 CDS Sez_1923 NC_011134.1 1985828 1987120 D similar to ref|ZP_00875692.1| Transposase, IS204/IS1001/IS1096/IS1165 [Streptococcus suis 89/1591]; transposase IS1193D 1985828..1987120 Streptococcus equi subsp. zooepidemicus MGCS10565 6761292 YP_002124258.1 CDS Sez_1924 NC_011134.1 1987162 1987434 R similar to ref|YP_061170.1| hypothetical protein M6_Spy1852 [Streptococcus pyogenes MGAS10394]; hypothetical protein complement(1987162..1987434) Streptococcus equi subsp. zooepidemicus MGCS10565 6761302 YP_002124259.1 CDS Sez_1925 NC_011134.1 1987451 1988827 R unwinds double stranded DNA; replicative DNA helicase complement(1987451..1988827) Streptococcus equi subsp. zooepidemicus MGCS10565 6761284 YP_002124260.1 CDS rplI NC_011134.1 1988848 1989300 R in Escherichia coli this protein is wrapped around the base of the L1 stalk; 50S ribosomal protein L9 complement(1988848..1989300) Streptococcus equi subsp. zooepidemicus MGCS10565 6761328 YP_002124261.1 CDS Sez_1927 NC_011134.1 1989297 1991273 R similar to ref|YP_599565.1| Phosphoesterase, DHH family protein [Streptococcus pyogenes MGAS10270]; phosphoesterase DHH family protein complement(1989297..1991273) Streptococcus equi subsp. zooepidemicus MGCS10565 6761282 YP_002124262.1 CDS Sez_1930 NC_011134.1 1993263 1993727 R similar to ref|YP_815645.1| MutT/nudix family protein [Streptococcus pneumoniae D39]; MutT/nudix family protein complement(1993263..1993727) Streptococcus equi subsp. zooepidemicus MGCS10565 6761350 YP_002124263.1 CDS mnmA NC_011134.1 1993932 1995056 R catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs; tRNA-specific 2-thiouridylase MnmA complement(1993932..1995056) Streptococcus equi subsp. zooepidemicus MGCS10565 6761258 YP_002124264.1 CDS Sez_1932 NC_011134.1 1995150 1995275 R hypothetical protein complement(1995150..1995275) Streptococcus equi subsp. zooepidemicus MGCS10565 6761274 YP_002124265.1 CDS sdaAB NC_011134.1 1995339 1996010 D similar to ref|YP_061176.1| L-serine dehydratase beta subunit [Streptococcus pyogenes MGAS10394]; Catalysis of the reaction: L-serine = pyruvate + NH3.; L-serine dehydratase subunit beta SdaAB 1995339..1996010 Streptococcus equi subsp. zooepidemicus MGCS10565 6761273 YP_002124266.1 CDS sdaAA NC_011134.1 1996022 1996894 D similar to ref|YP_599570.1| L-serinedehydratase alpha subunit [Streptococcus pyogenes MGAS10270]; Catalysis of the reaction: L-serine = pyruvate + NH3.; L-serine dehydratase subunit alpha SdaAA 1996022..1996894 Streptococcus equi subsp. zooepidemicus MGCS10565 6761202 YP_002124267.1 CDS Sez_1935 NC_011134.1 1996928 1997563 D similar to ref|YP_001036270.1| Phosphoglycolate phosphatase, [Streptococcus sanguinis SK36]; Catalysis of the reaction: 2-phosphoglycolate + H2O = glycolate + phosphate.; phosphoglycolate phosphatase 1996928..1997563 Streptococcus equi subsp. zooepidemicus MGCS10565 6761270 YP_002124268.1 CDS Sez_1936 NC_011134.1 1997625 1998236 R similar to ref|YP_597585.1| transglycosylase SLT domain family protein [Streptococcus pyogenes MGAS9429]; hypothetical protein complement(1997625..1998236) Streptococcus equi subsp. zooepidemicus MGCS10565 6761269 YP_002124269.1 CDS cbiO NC_011134.1 1998491 1999300 R similar to ref|ZP_00366389.1| COG0619: ABC-type cobalt transport system, permease component CbiQ and related transporters [Streptococcus pyogenes M49 591]; Part of the ABC transporter complex cbiONQ involved in cobalt import. Transmembrane domains (TMD) form a pore in the membrane and the ATP-binding domain (NBD) is responsible for energy generation.; cobalt import ATP-binding/permease CbiO complement(1998491..1999300) Streptococcus equi subsp. zooepidemicus MGCS10565 6761265 YP_002124270.1 CDS cbiO NC_011134.1 1999293 2000135 R with CbiNQ forms the ABC transporter for cobalt import; Streptococcus has two adjacent copies of this gene; cobalt transporter ATP-binding subunit complement(1999293..2000135) Streptococcus equi subsp. zooepidemicus MGCS10565 6761264 YP_002124271.1 CDS cbiO NC_011134.1 2000111 2000950 R with CbiNQ forms the ABC transporter for cobalt import; Streptococcus has two adjacent copies of this gene; cobalt transporter ATP-binding subunit complement(2000111..2000950) Streptococcus equi subsp. zooepidemicus MGCS10565 6761242 YP_002124272.1 CDS pgsA NC_011134.1 2000953 2001495 R similar to gb|ABW75773.1| CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase [Streptococcus equi subsp. zooepidemicus]; Catalysis of the reaction: CDP-diacylglycerol + glycerol 3-phosphate = CMP + 3-(3-phosphatidyl)-glycerol 1-phosphate.; CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase complement(2000953..2001495) Streptococcus equi subsp. zooepidemicus MGCS10565 6761259 YP_002124273.1 CDS Sez_1941 NC_011134.1 2001508 2001966 R similar to ref|ZP_00366385.1| COG1426: Uncharacterized protein conserved in bacteria [Streptococcus pyogenes M49 591]; hypothetical protein complement(2001508..2001966) Streptococcus equi subsp. zooepidemicus MGCS10565 6761238 YP_002124274.1 CDS Sez_1942 NC_011134.1 2001920 2002513 R similar to ref|YP_281345.1| hypothetical membrane associated protein [Streptococcus pyogenes MGAS6180]; hypothetical protein complement(2001920..2002513) Streptococcus equi subsp. zooepidemicus MGCS10565 6761334 YP_002124275.1 CDS Sez_1943 NC_011134.1 2002563 2003846 R similar to ref|YP_603459.1| Zinc protease [Streptococcus pyogenes MGAS10750]; zinc protease complement(2002563..2003846) Streptococcus equi subsp. zooepidemicus MGCS10565 6761333 YP_002124276.1 CDS Sez_1944 NC_011134.1 2003848 2005092 R similar to ref|YP_061185.1| Zinc protease [Streptococcus pyogenes MGAS10394]; zinc protease complement(2003848..2005092) Streptococcus equi subsp. zooepidemicus MGCS10565 6761329 YP_002124277.1 CDS Sez_1945 NC_011134.1 2005301 2005720 D similar to ref|YP_597596.1| hypothetical cytosolic protein [Streptococcus pyogenes MGAS9429]; hypothetical protein 2005301..2005720 Streptococcus equi subsp. zooepidemicus MGCS10565 6761330 YP_002124278.1 CDS recF NC_011134.1 2005722 2006831 D Required for DNA replication; binds preferentially to single-stranded, linear DNA; recombination protein F 2005722..2006831 Streptococcus equi subsp. zooepidemicus MGCS10565 6761303 YP_002124279.1 CDS Sez_1947 NC_011134.1 2006895 2007728 R similar to ref|YP_283219.1| glucose uptake protein homolog [Streptococcus pyogenes MGAS5005]; sugar uptake protein complement(2006895..2007728) Streptococcus equi subsp. zooepidemicus MGCS10565 6761324 YP_002124280.1 CDS Sez_1948 NC_011134.1 2007929 2010358 R similar to ref|NP_466326.1| hypothetical protein lmo2804 [Listeria monocytogenes EGD-e]; hypothetical protein complement(2007929..2010358) Streptococcus equi subsp. zooepidemicus MGCS10565 6761321 YP_002124281.1 CDS Sez_1949 NC_011134.1 2010361 2010756 R similar to ref|YP_001034253.1| hypothetical protein SSA_0244 [Streptococcus sanguinis SK36]; hypothetical protein complement(2010361..2010756) Streptococcus equi subsp. zooepidemicus MGCS10565 6761293 YP_002124282.1 CDS Sez_1950 NC_011134.1 2010753 2011154 R similar to ref|YP_001034253.1| hypothetical protein SSA_0244 [Streptococcus sanguinis SK36]; hypothetical protein complement(2010753..2011154) Streptococcus equi subsp. zooepidemicus MGCS10565 6761288 YP_002124283.1 CDS Sez_1951 NC_011134.1 2011151 2011552 R similar to ref|ZP_01928725.1| hypothetical protein LMHG_00511 [Listeria monocytogenes FSL N1-017]; hypothetical protein complement(2011151..2011552) Streptococcus equi subsp. zooepidemicus MGCS10565 6761285 YP_002124284.1 CDS Sez_1952 NC_011134.1 2011718 2011849 D hypothetical protein 2011718..2011849 Streptococcus equi subsp. zooepidemicus MGCS10565 6762348 YP_002124285.1 CDS guaB NC_011134.1 2011933 2013414 R catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate; inosine 5'-monophosphate dehydrogenase complement(2011933..2013414) Streptococcus equi subsp. zooepidemicus MGCS10565 6761125 YP_002124286.1 CDS trpS NC_011134.1 2013615 2014637 R catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; tryptophanyl-tRNA synthetase complement(2013615..2014637) Streptococcus equi subsp. zooepidemicus MGCS10565 6761109 YP_002124287.1 CDS Sez_1955 NC_011134.1 2015054 2015644 D similar to ref|NP_270115.1| hypothetical protein SPy_2209 [Streptococcus pyogenes M1 GAS]; hypothetical protein 2015054..2015644 Streptococcus equi subsp. zooepidemicus MGCS10565 6761160 YP_002124288.1 CDS Sez_1956 NC_011134.1 2015641 2015925 D similar to ref|YP_001129344.1| hypothetical protein SpyM51832 [Streptococcus pyogenes str. Manfredo]; hypothetical protein 2015641..2015925 Streptococcus equi subsp. zooepidemicus MGCS10565 6761161 YP_002124289.1 CDS Sez_1957 NC_011134.1 2016005 2017624 D similar to ref|NP_270116.1| ABC transporter, ATP-binding protein [Streptococcus pyogenes M1 GAS]; ABC transporter ATP-binding protein 2016005..2017624 Streptococcus equi subsp. zooepidemicus MGCS10565 6761177 YP_002124290.1 CDS Sez_1958 NC_011134.1 2017748 2020333 D similar to ref|NP_665665.1| ABC transporter, permease [Streptococcus pyogenes MGAS315]; ABC transporter permease 2017748..2020333 Streptococcus equi subsp. zooepidemicus MGCS10565 6761184 YP_002124291.1 CDS Sez_1959 NC_011134.1 2021365 2021844 R SPOUT methyltransferase family protein; crystal structure shows homodimer; in Escherichia coli this protein methylates pseudouridine at position 1915 of the 23S ribosomal RNA; rRNA large subunit methyltransferase complement(2021365..2021844) Streptococcus equi subsp. zooepidemicus MGCS10565 6761148 YP_002124292.1 CDS Sez_1960 NC_011134.1 2022054 2023277 D similar to ref|NP_270119.1| serine protease [Streptococcus pyogenes M1 GAS]; Degrades abnormal exported proteins. Needed for the propeptide processing of a natural pro-protein and for the maturation of a native protein. Responsible for the housekeeping of exported proteins.; serine protease do-like HtrA 2022054..2023277 Streptococcus equi subsp. zooepidemicus MGCS10565 6761178 YP_002124293.1 CDS parB NC_011134.1 2023397 2024170 D similar to ref|YP_061204.1| Chromosome partitioning protein [Streptococcus pyogenes MGAS10394]; Required for the initiation of sporulation and for normal chromosome segregation. Antagonizes sporulation inhibition of soj. It probably interacts with a specific DNA site and other proteins involved in partitioning and cell division, and antagonizes soj in response to cell cycle events related to chromosome partitioning.; chromosome partitioning ATPase 2023397..2024170 Streptococcus equi subsp. zooepidemicus MGCS10565 6761175 Sez_1963 tRNA Sez_1963 NC_011134.1 19868 19945 D tRNA-Ala 19868..19945 Streptococcus equi subsp. zooepidemicus MGCS10565 6761132 Sez_1966 tRNA Sez_1966 NC_011134.1 23348 23423 D tRNA-Val 23348..23423 Streptococcus equi subsp. zooepidemicus MGCS10565 6761114 Sez_1967 tRNA Sez_1967 NC_011134.1 23434 23509 D tRNA-Asp 23434..23509 Streptococcus equi subsp. zooepidemicus MGCS10565 6761038 Sez_1968 tRNA Sez_1968 NC_011134.1 23510 23585 D tRNA-Lys 23510..23585 Streptococcus equi subsp. zooepidemicus MGCS10565 6761082 Sez_1969 tRNA Sez_1969 NC_011134.1 23588 23672 D tRNA-Leu 23588..23672 Streptococcus equi subsp. zooepidemicus MGCS10565 6761080 Sez_1970 tRNA Sez_1970 NC_011134.1 23678 23753 D tRNA-Thr 23678..23753 Streptococcus equi subsp. zooepidemicus MGCS10565 6761079 Sez_1971 tRNA Sez_1971 NC_011134.1 23762 23836 D tRNA-Gly 23762..23836 Streptococcus equi subsp. zooepidemicus MGCS10565 6761075 Sez_1972 tRNA Sez_1972 NC_011134.1 23842 23929 D tRNA-Leu 23842..23929 Streptococcus equi subsp. zooepidemicus MGCS10565 6761090 Sez_1973 tRNA Sez_1973 NC_011134.1 23941 24017 D tRNA-Arg 23941..24017 Streptococcus equi subsp. zooepidemicus MGCS10565 6761091 Sez_1974 tRNA Sez_1974 NC_011134.1 24021 24097 D tRNA-Pro 24021..24097 Streptococcus equi subsp. zooepidemicus MGCS10565 6761072 Sez_1975 tRNA Sez_1975 NC_011134.1 24104 24182 D tRNA-Met 24104..24182 Streptococcus equi subsp. zooepidemicus MGCS10565 6761085 Sez_1976 tRNA Sez_1976 NC_011134.1 24198 24276 D tRNA-Met 24198..24276 Streptococcus equi subsp. zooepidemicus MGCS10565 6761089 Sez_1977 tRNA Sez_1977 NC_011134.1 24280 24372 D tRNA-Ser 24280..24372 Streptococcus equi subsp. zooepidemicus MGCS10565 6761060 Sez_1978 tRNA Sez_1978 NC_011134.1 24380 24458 D tRNA-Met 24380..24458 Streptococcus equi subsp. zooepidemicus MGCS10565 6761073 Sez_1979 tRNA Sez_1979 NC_011134.1 24478 24555 D tRNA-Phe 24478..24555 Streptococcus equi subsp. zooepidemicus MGCS10565 6761070 Sez_1980 tRNA Sez_1980 NC_011134.1 24556 24631 D tRNA-Gly 24556..24631 Streptococcus equi subsp. zooepidemicus MGCS10565 6761069 Sez_1981 tRNA Sez_1981 NC_011134.1 24656 24734 D tRNA-Ile 24656..24734 Streptococcus equi subsp. zooepidemicus MGCS10565 6761065 Sez_1982 tRNA Sez_1982 NC_011134.1 24739 24831 D tRNA-Ser 24739..24831 Streptococcus equi subsp. zooepidemicus MGCS10565 6761045 Sez_1984 tRNA Sez_1984 NC_011134.1 89986 90063 D tRNA-Ala 89986..90063 Streptococcus equi subsp. zooepidemicus MGCS10565 6761063 Sez_1987 tRNA Sez_1987 NC_011134.1 93466 93541 D tRNA-Val 93466..93541 Streptococcus equi subsp. zooepidemicus MGCS10565 6761052 Sez_1988 tRNA Sez_1988 NC_011134.1 93543 93618 D tRNA-Gly 93543..93618 Streptococcus equi subsp. zooepidemicus MGCS10565 6761033 Sez_1989 tRNA Sez_1989 NC_011134.1 93643 93721 D tRNA-Ile 93643..93721 Streptococcus equi subsp. zooepidemicus MGCS10565 6761049 Sez_1990 tRNA Sez_1990 NC_011134.1 93729 93805 D tRNA-Glu 93729..93805 Streptococcus equi subsp. zooepidemicus MGCS10565 6761039 Sez_1991 tRNA Sez_1991 NC_011134.1 93812 93904 D tRNA-Ser 93812..93904 Streptococcus equi subsp. zooepidemicus MGCS10565 6761216 Sez_1992 tRNA Sez_1992 NC_011134.1 93912 93990 D tRNA-Met 93912..93990 Streptococcus equi subsp. zooepidemicus MGCS10565 6761027 Sez_1993 tRNA Sez_1993 NC_011134.1 94010 94087 D tRNA-Phe 94010..94087 Streptococcus equi subsp. zooepidemicus MGCS10565 6761128 Sez_1994 tRNA Sez_1994 NC_011134.1 94102 94187 D tRNA-Tyr 94102..94187 Streptococcus equi subsp. zooepidemicus MGCS10565 6761187 Sez_1995 tRNA Sez_1995 NC_011134.1 94190 94263 D tRNA-Trp 94190..94263 Streptococcus equi subsp. zooepidemicus MGCS10565 6760494 Sez_1996 tRNA Sez_1996 NC_011134.1 94271 94348 D tRNA-His 94271..94348 Streptococcus equi subsp. zooepidemicus MGCS10565 6760590 Sez_1997 tRNA Sez_1997 NC_011134.1 94352 94428 D tRNA-Gln 94352..94428 Streptococcus equi subsp. zooepidemicus MGCS10565 6760416 Sez_1998 tRNA Sez_1998 NC_011134.1 94443 94529 D tRNA-Leu 94443..94529 Streptococcus equi subsp. zooepidemicus MGCS10565 6760758 Sez_1999 tRNA Sez_1999 NC_011134.1 150252 150325 D tRNA-Cys 150252..150325 Streptococcus equi subsp. zooepidemicus MGCS10565 6762269 Sez_2000 tRNA Sez_2000 NC_011134.1 461995 462084 D tRNA-Ser 461995..462084 Streptococcus equi subsp. zooepidemicus MGCS10565 6760446 Sez_2001 tRNA Sez_2001 NC_011134.1 784783 784857 D tRNA-Arg 784783..784857 Streptococcus equi subsp. zooepidemicus MGCS10565 6761524 Sez_2003 tRNA Sez_2003 NC_011134.1 1182618 1182692 R tRNA-Arg complement(1182618..1182692) Streptococcus equi subsp. zooepidemicus MGCS10565 6762082 Sez_2004 tRNA Sez_2004 NC_011134.1 1185891 1185967 R tRNA-Gln complement(1185891..1185967) Streptococcus equi subsp. zooepidemicus MGCS10565 6762070 Sez_2005 tRNA Sez_2005 NC_011134.1 1186002 1186085 R tRNA-Tyr complement(1186002..1186085) Streptococcus equi subsp. zooepidemicus MGCS10565 6761165 Sez_2006 tRNA Sez_2006 NC_011134.1 1524368 1524441 R tRNA-Thr complement(1524368..1524441) Streptococcus equi subsp. zooepidemicus MGCS10565 6762111 Sez_2007 tRNA Sez_2007 NC_011134.1 1587838 1587914 R tRNA-Glu complement(1587838..1587914) Streptococcus equi subsp. zooepidemicus MGCS10565 6761885 Sez_2008 tRNA Sez_2008 NC_011134.1 1587922 1588000 R tRNA-Ile complement(1587922..1588000) Streptococcus equi subsp. zooepidemicus MGCS10565 6761152 Sez_2009 tRNA Sez_2009 NC_011134.1 1588042 1588117 R tRNA-Thr complement(1588042..1588117) Streptococcus equi subsp. zooepidemicus MGCS10565 6761151 Sez_2010 tRNA Sez_2010 NC_011134.1 1588123 1588207 R tRNA-Leu complement(1588123..1588207) Streptococcus equi subsp. zooepidemicus MGCS10565 6761130 Sez_2011 tRNA Sez_2011 NC_011134.1 1588210 1588285 R tRNA-Lys complement(1588210..1588285) Streptococcus equi subsp. zooepidemicus MGCS10565 6761126 Sez_2012 tRNA Sez_2012 NC_011134.1 1588286 1588361 R tRNA-Asp complement(1588286..1588361) Streptococcus equi subsp. zooepidemicus MGCS10565 6761121 Sez_2013 tRNA Sez_2013 NC_011134.1 1588372 1588447 R tRNA-Val complement(1588372..1588447) Streptococcus equi subsp. zooepidemicus MGCS10565 6761119 Sez_2016 tRNA Sez_2016 NC_011134.1 1591850 1591927 R tRNA-Ala complement(1591850..1591927) Streptococcus equi subsp. zooepidemicus MGCS10565 6761171 Sez_2018 tRNA Sez_2018 NC_011134.1 1734124 1734200 R tRNA-Arg complement(1734124..1734200) Streptococcus equi subsp. zooepidemicus MGCS10565 6762168 Sez_2019 tRNA Sez_2019 NC_011134.1 1734436 1734512 R tRNA-Asn complement(1734436..1734512) Streptococcus equi subsp. zooepidemicus MGCS10565 6762179 Sez_2022 tRNA Sez_2022 NC_011134.1 1737906 1737983 R tRNA-Ala complement(1737906..1737983) Streptococcus equi subsp. zooepidemicus MGCS10565 6761118 Sez_2024 tRNA Sez_2024 NC_011134.1 1768354 1768442 R tRNA-Leu complement(1768354..1768442) Streptococcus equi subsp. zooepidemicus MGCS10565 6762023 Sez_2025 tRNA Sez_2025 NC_011134.1 1782049 1782125 R tRNA-Arg complement(1782049..1782125) Streptococcus equi subsp. zooepidemicus MGCS10565 6762013 Sez_2026 tRNA Sez_2026 NC_011134.1 1782361 1782437 R tRNA-Asn complement(1782361..1782437) Streptococcus equi subsp. zooepidemicus MGCS10565 6762007 Sez_2029 tRNA Sez_2029 NC_011134.1 1785831 1785908 R tRNA-Ala complement(1785831..1785908) Streptococcus equi subsp. zooepidemicus MGCS10565 6761104 Sez_2031 tRNA Sez_2031 NC_011134.1 1860213 1860290 D tRNA-Lys 1860213..1860290 Streptococcus equi subsp. zooepidemicus MGCS10565 6761625 Sez_2032 tRNA Sez_2032 NC_011134.1 2020530 2020608 R tRNA-Asn complement(2020530..2020608) Streptococcus equi subsp. zooepidemicus MGCS10565 6761159 Sez_2033 tRNA Sez_2033 NC_011134.1 2020637 2020711 R tRNA-Glu complement(2020637..2020711) Streptococcus equi subsp. zooepidemicus MGCS10565 6761157 Sez_2034 tRNA Sez_2034 NC_011134.1 2020992 2021068 D tRNA-Arg 2020992..2021068 Streptococcus equi subsp. zooepidemicus MGCS10565 6761133 Sez_1962 rRNA Sez_1962 NC_011134.1 18340 19674 D 16S ribosomal RNA 18340..19674 Streptococcus equi subsp. zooepidemicus MGCS10565 6761506 Sez_1964 rRNA Sez_1964 NC_011134.1 20203 23100 D 23S ribosomal RNA 20203..23100 Streptococcus equi subsp. zooepidemicus MGCS10565 6761154 Sez_1965 rRNA Sez_1965 NC_011134.1 23187 23302 D 5S ribosomal RNA 23187..23302 Streptococcus equi subsp. zooepidemicus MGCS10565 6761167 Sez_1983 rRNA Sez_1983 NC_011134.1 88458 89792 D 16S ribosomal RNA 88458..89792 Streptococcus equi subsp. zooepidemicus MGCS10565 6760436 Sez_1985 rRNA Sez_1985 NC_011134.1 90321 93218 D 23S ribosomal RNA 90321..93218 Streptococcus equi subsp. zooepidemicus MGCS10565 6761040 Sez_1986 rRNA Sez_1986 NC_011134.1 93305 93420 D 5S ribosomal RNA 93305..93420 Streptococcus equi subsp. zooepidemicus MGCS10565 6761054 Sez_2014 rRNA Sez_2014 NC_011134.1 1588431 1588546 R 5S ribosomal RNA complement(1588431..1588546) Streptococcus equi subsp. zooepidemicus MGCS10565 6761123 Sez_2015 rRNA Sez_2015 NC_011134.1 1588633 1591530 R 23S ribosomal RNA complement(1588633..1591530) Streptococcus equi subsp. zooepidemicus MGCS10565 6761112 Sez_2017 rRNA Sez_2017 NC_011134.1 1592057 1593393 R 16S ribosomal RNA complement(1592057..1593393) Streptococcus equi subsp. zooepidemicus MGCS10565 6761099 Sez_2020 rRNA Sez_2020 NC_011134.1 1734487 1734602 R 5S ribosomal RNA complement(1734487..1734602) Streptococcus equi subsp. zooepidemicus MGCS10565 6761097 Sez_2021 rRNA Sez_2021 NC_011134.1 1734689 1737586 R 23S ribosomal RNA complement(1734689..1737586) Streptococcus equi subsp. zooepidemicus MGCS10565 6761117 Sez_2023 rRNA Sez_2023 NC_011134.1 1738115 1739449 R 16S ribosomal RNA complement(1738115..1739449) Streptococcus equi subsp. zooepidemicus MGCS10565 6761043 Sez_2027 rRNA Sez_2027 NC_011134.1 1782412 1782527 R 5S ribosomal RNA complement(1782412..1782527) Streptococcus equi subsp. zooepidemicus MGCS10565 6761103 Sez_2028 rRNA Sez_2028 NC_011134.1 1782614 1785511 R 23S ribosomal RNA complement(1782614..1785511) Streptococcus equi subsp. zooepidemicus MGCS10565 6761087 Sez_2030 rRNA Sez_2030 NC_011134.1 1786040 1787374 R 16S ribosomal RNA complement(1786040..1787374) Streptococcus equi subsp. zooepidemicus MGCS10565 6761083