-- dump date 20140620_082951 -- class Genbank::CDS -- table cds_note -- id note YP_003445189.1 sigma factor YP_003445190.1 COG2826, IS30 family YP_003445200.1 COG2826, IS30 family YP_003445204.1 COG5263, glucan-binding domain (YG repeat) YP_003445205.1 COG5263, glucan-binding domain (YG repeat) YP_003445206.1 COG3436, IS66 family YP_003445207.1 COG3436, IS66 family YP_003445209.1 COG2826, IS30 family YP_003445213.1 COG3335 YP_003445216.1 CoA binding protein YP_003445219.1 DNA repair protein Rec0 YP_003445222.1 COG5263, glucan-binding domain (YG repeat) YP_003445224.1 COG5263, glucan-binding domain (YG repeat) YP_003445225.1 bacteriocin/pheromone -type, double glycine-cleavage motif YP_003445226.1 pheromone receptor, comD-type YP_003445227.1 response regulator of the LytR/AlgR family YP_003445228.1 bacteriocin/pheromone -type, double glycine-cleavage motif YP_003445229.1 bacteriocin/pheromone -type, double glycine-cleavage motif YP_003445230.1 bacteriocin/pheromone -type, double glycine-cleavage motif YP_003445231.1 two TM-helices predicted YP_003445232.1 bacteriocin/pheromone -type, double glycine-cleavage motif YP_003445233.1 two TM-helices predicted YP_003445234.1 two TM-helices predicted YP_003445242.1 pfam00583, acetyltransferase (GNAT) family. YP_003445248.1 COG3464 YP_003445256.1 COG5263, glucan-binding domain (YG repeat) YP_003445258.1 COG2820, similar to uridine phosphorylase YP_003445259.1 COG0168, TrkG, Trk-type K+ transport system, membrane component YP_003445260.1 COG0569, TrkA, K+ transport system, NAD-binding component YP_003445261.1 COG0463, glycosyltransferases involved in cell wall biogenesis YP_003445262.1 LPXTG motif, contains 4 repeats of 456-bp SSURE domain YP_003445263.1 DNA-binding response regulator YP_003445270.1 COG3668 YP_003445271.1 membrane protein, 1 TM-helic predicted YP_003445272.1 COG3853, toxic anion resistance protein YP_003445273.1 COG0640, cadmium efflux system transcriptional regulator YP_003445277.1 COG2826, IS30 family YP_003445293.1 5 TM helices predicted YP_003445296.1 pfam02517 YP_003445297.1 bacteriocin/pheromone -type, double glycine-cleavage motif YP_003445311.1 COG2826, IS30 family YP_003445325.1 COG2071, predicted glutamine amidotransferases YP_003445326.1 pfam01797 YP_003445331.1 transcriptional regulator, COPG family YP_003445345.1 glutamylcysteine synthetase YP_003445348.1 COG0546, phosphatase YP_003445349.1 COG1388: LysM repeat; Lysin domain, found in a variety of enzymes involved in bacterial cell wall degradation YP_003445351.1 COG5523, predicted integral membrane protein YP_003445353.1 cd01840, esterase YP_003445354.1 COG2826, IS30 family YP_003445363.1 competence protein YP_003445369.1 preprotein translocase subunit YidC1 (intracellular trafficking and secretion); COG0706 YP_003445370.1 COG1847, jag, predicted RNA-binding protein YP_003445378.1 transcriptional regulator, BglG family YP_003445381.1 COG1862 YP_003445382.1 phosphotyrosine protein phosphatase YP_003445386.1 COG0564, RluA, pseudouridylate synthases, 23S RNA-specific YP_003445388.1 COG2826, IS30 family YP_003445393.1 COG2826, IS30 family YP_003445397.1 ABC transporter permease YP_003445399.1 DNA-binding response regulator YP_003445400.1 COG2826, IS30 family YP_003445407.1 COG1187, 16S_rRNA pseudouridylate synthase and related pseudouridylate synthases YP_003445409.1 pfam01610 YP_003445411.1 membrane bound lipoprotein YP_003445418.1 pfam02517 YP_003445427.1 universal stress protein family YP_003445432.1 COG0531 YP_003445438.1 COG1564, THI80 YP_003445441.1 COG2826, IS30 family YP_003445450.1 preprotein translocase subunit YidC2 (intracellular trafficking and secretion); COG0706 YP_003445456.1 COG3480, SdrC, predicted secreted protein containing a PDZ domain YP_003445460.1 hemolysins and related proteins containing CBS domains [General function prediction only]; COG1253; Domain of unknown function DUF21. This transmembrane region has no known function. Many of the sequences in this family are annotated as hemolysins, however this is due to a similarity to a protein, which does not contain this domain. YP_003445466.1 COG2984, ABC-type transport system YP_003445467.1 COG 4120 YP_003445478.1 COG1187, 16S_rRNA pseudouridylate synthase and related pseudouridylate synthases YP_003445484.1 LPXTG motif YP_003445495.1 4-methyl-5(B-hydroxyethyl)-thiazole monophosphate biosynthesis enzyme YP_003445498.1 COG3666 YP_003445500.1 HIT family protein YP_003445501.1 This family of ATP-binding proteins belongs to a multisubunit transporter involved in drug resistance (BcrA and DrrA), nodulation, lipid transport, and lantibiotic immunity. In bacteria and archaea, these transporters usually include an ATP-binding protein and one or two integral membrane proteins. YP_003445506.1 Peptide pheromone receptor, ComD type YP_003445508.1 two TM-helices predicted YP_003445510.1 four TM-helices predicted YP_003445511.1 two TM-helices predicted YP_003445512.1 pfam02517 YP_003445514.1 COG0220 YP_003445516.1 COG0195 YP_003445518.1 pfam01248 YP_003445525.1 COG1204, superfamily II helicase YP_003445527.1 COG1670, RimL, acetyltransferases, including N-acetylases of ribosomal proteins YP_003445528.1 COG0703, shikimate kinase YP_003445529.1 COG0525, valyl-tRNA synthetase YP_003445531.1 COG0326, molecular chaperone, HSP90 family YP_003445533.1 COG2184 YP_003445534.1 COG1061 YP_003445538.1 COG0577 YP_003445539.1 COG2826, IS30 family YP_003445541.1 COG0504, COG2071 YP_003445542.1 COG5263, glucan-binding domain (YG repeat) YP_003445544.1 COG0526: thiol-disulfide isomerase and thioredoxins YP_003445552.1 phage associated YP_003445553.1 phage associated YP_003445561.1 COG0593 YP_003445564.1 pfam09250, Prim-Pol, bifunctional DNA primase/polymerase YP_003445565.1 COG3378, ATPase, phage associated YP_003445566.1 phage associated YP_003445571.1 phage associated YP_003445572.1 phage associated YP_003445579.1 pfam02452 YP_003445584.1 COG2766 YP_003445585.1 COG5585 YP_003445587.1 phage associated YP_003445588.1 phage associated YP_003445589.1 phage associated YP_003445591.1 COG0840 YP_003445603.1 COG1652 YP_003445607.1 COG3299 YP_003445618.1 COG5263, glucan-binding domain (YG repeat) YP_003445619.1 COG3666 YP_003445625.1 COG1396 YP_003445626.1 COG3557 YP_003445629.1 COG0340.1 YP_003445630.1 COG2826, IS30 family YP_003445631.1 COG3307, RfaL, lipid A core - O-antigen ligase and related enzymes YP_003445640.1 COG2050: uncharacterized protein, possibly involved in aromatic compounds catabolism YP_003445645.1 pfam00860 YP_003445649.1 COG1266 YP_003445650.1 COG0640 YP_003445651.1 COG5658, predicted integral membrane protein, lipoprotein signature YP_003445653.1 COG2323 YP_003445654.1 MsbA is an ABC transporter, closely related to eukaryotic MDR proteins YP_003445656.1 COG2148, WcaJ, sugar transferases involved in lipopolysaccharide synthesis YP_003445657.1 predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis COG0399 YP_003445666.1 COG1989 YP_003445667.1 COG1670, acetyltransferases, including N-acetylases of ribosomal proteins YP_003445673.1 pfam05043, Mga, M protein trans-acting positive regulator (MGA). Mga is a DNA-binding protein that activates the expression of several important virulence genes in group A streptococcus in response to changing environmental conditions. YP_003445675.1 COG0604 YP_003445676.1 COG1959 YP_003445682.1 COG1164 YP_003445685.1 cd00333, MIP, Major intrinsic protein (MIP) superfamily YP_003445686.1 COG0780, enzyme related to GTP cyclohydrolase I YP_003445687.1 Coenzyme PQQ synthesis homologue YP_003445688.1 COG0720 YP_003445693.1 COG1380 YP_003445694.1 pfam04172, LrgB, LrgB-like family. The two products of the lrgAB operon are potential membrane proteins, and LrgA and LrgB are both thought to control of murein hydrolase activity and penicillin tolerance YP_003445695.1 COG1132 YP_003445697.1 COG1131 YP_003445698.1 HTH motif YP_003445699.1 ATP cone domain protein YP_003445700.1 COG3611 YP_003445702.1 COG0778 YP_003445706.1 COG0653 YP_003445709.1 COG0736 YP_003445713.1 pfam02371 YP_003445714.1 pfam 01548 YP_003445716.1 COG1670, acetyltransferase, GNAT family YP_003445718.1 LPXTG motif YP_003445728.1 plasmid stabilization system protein superfamily, RelE/ParE family protein YP_003445729.1 pfam01380, SIS domain. SIS (Sugar ISomerase) domains are found in many phosphosugar isomerases and phosphosugar binding proteins. SIS domains are also found in proteins that regulate the expression of genes involved in synthesis of phosphosugars. Presumably the SIS domains bind to the end-product of the pathway YP_003445735.1 COG2826, IS30 family YP_003445736.1 COG2826, IS30 family YP_003445739.1 COG0325, enzyme with a TIM-barrel fold YP_003445742.1 COG2302, contains S4-like domain YP_003445748.1 COG1136 YP_003445754.1 10 TM helices predicted YP_003445756.1 COG3590, metalloendopeptidase YP_003445757.1 COG0491, Zn-dependent hydrolases YP_003445763.1 COG0622, predicted phosphoesterase YP_003445764.1 COG1959, predicted transcriptional regulator, Rrf2 family protein YP_003445766.1 DNA-binding response regulator YP_003445769.1 7 TM helices YP_003445779.1 COG2826, IS30 family YP_003445780.1 COG0474 YP_003445781.1 COG2384, SAM-dependent methyltransferase YP_003445783.1 DadA, glycine D-amino acid oxidases YP_003445784.1 DadA, glycine D-amino acid oxidases YP_003445786.1 COG0463, glycosyltransferases involved in cell wall biogenesis YP_003445787.1 COG1141 YP_003445797.1 COG3442, glutamine amidotransferase YP_003445800.1 pfam00909 YP_003445802.1 COG0513 YP_003445803.1 COG2826, IS30 family YP_003445805.1 COG1335 YP_003445806.1 COG4591, ABC-type transport system, involved in lipoprotein release YP_003445809.1 DNA-binding response regulator YP_003445813.1 plasmid stabilization system antitoxin protein YP_003445814.1 COG1185: polyribonucleotide nucleotidyltransferase YP_003445816.1 pfam00300 YP_003445819.1 5 TM helices YP_003445820.1 LPXTG motif YP_003445824.1 COG0500 YP_003445826.1 COG0025 YP_003445831.1 COG1493, serine kinase of the HPr protein, regulates carbohydrate metabolism YP_003445839.1 smart00530, HTH_XRE, helix-turn-helix XRE-family like proteins YP_003445840.1 COG5263, glucan binding domain (YG repeat) YP_003445841.1 COG5263, glucan binding domain (YG repeat) YP_003445842.1 membrane bound lipoprotein YP_003445843.1 cd03032, ArsC_Spx, arsenate reductase (ArsC) family, Spx subfamily YP_003445845.1 cd01637, IMPase_like, inositol-monophosphatase-like domains YP_003445846.1 COG0144, sun, tRNA and rRNA cytosine-C5-methylases [ YP_003445847.1 COG0226 YP_003445853.1 COG0834 YP_003445854.1 COG1167, ARO8, transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) YP_003445859.1 COG1176 YP_003445860.1 COG1177 YP_003445862.1 COG2826, IS30 family YP_003445868.1 COG1368 YP_003445876.1 COG1704 YP_003445881.1 COG1316, LytR YP_003445882.1 pfam04991 YP_003445883.1 COG0438, RfaG; pfam00534, glycosyl transferases group 1 YP_003445884.1 pfam00535, glycosyl transferase group 2 YP_003445887.1 pfam05389, negative regulator of genetic competence in Bacillus subtilis YP_003445891.1 COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components YP_003445892.1 COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components YP_003445894.1 COG2826, IS30 family YP_003445895.1 COG2826, IS30 family YP_003445896.1 COG2826, IS30 family YP_003445897.1 COG2826, IS30 family YP_003445901.1 pfam06970, RepA_N, replication initiator protein A (RepA) N-terminus YP_003445904.1 COG1393, ArsC, Arsenate reductase and related proteins, glutaredoxin family YP_003445906.1 pfam02517 YP_003445907.1 COG1737, RpiR YP_003445910.1 COG0591, PutP, Na+/proline symporter; pfam00474, SSF YP_003445912.1 pfam01408, GFO_IDH_MocA, oxidoreductase family; COG0673, MviM, predicted dehydrogenases and related proteins YP_003445913.1 COG1940, NagC, transcriptional regulator/sugar kinase; pfam00480, ROK YP_003445915.1 COG1269, NtpI, archaeal/vacuolar-type H+-ATPase subunit I YP_003445916.1 COG0636, AtpE, F0F1-type ATP synthase, subunit c/Archaeal/vacuolar-type H+-ATPase, subunit K YP_003445918.1 COG1527, NtpC, Archaeal/vacuolar-type H+-ATPase subunit C YP_003445919.1 COG1436, NtpG, Archaeal/vacuolar-type H+-ATPase subunit F YP_003445920.1 COG1155, NtpA, Archaeal/vacuolar-type H+-ATPase subunit A YP_003445921.1 COG1156, NtpB, Archaeal/vacuolar-type H+-ATPase subunit B YP_003445922.1 pfam01813, ATP-synt_D, ATP synthase subunit D YP_003445923.1 pfam01797 YP_003445924.1 pfam01797 YP_003445925.1 LPXTG motif YP_003445926.1 pfam01797 YP_003445927.1 pfam01797 YP_003445928.1 pfam01797 YP_003445929.1 COG0334, GdhA, glutamate dehydrogenase/leucine dehydrogenase YP_003445930.1 COG0167, PyrD, dihydroorotate dehydrogenase; pfam01180, DHO_dh, dihydroorotate dehydrogenase YP_003445932.1 COG0605, SodA, superoxide dismutase YP_003445934.1 COG0820, predicted Fe-S-cluster redox enzyme YP_003445935.1 COG4767, VanZ, glycopeptide antibiotics resistance protein; pfam04892, VanZ like family YP_003445936.1 COG0488, Uup, ATPase components of ABC transporters with duplicated ATPase domains YP_003445937.1 cyclophilin_WD40: cyclophilin-type peptidylprolyl cis- trans isomerases YP_003445942.1 COG1837, predicted RNA-binding protein (contains KH domain) YP_003445944.1 COG0596, MhpC, predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily); pfam00561, Abhydrolase_1, alpha/beta hydrolase fold YP_003445946.1 pfam01746, tRNA_m1G_MT, tRNA (Guanine-N(1)-)-methyltransferase YP_003445947.1 COG1328, NrdD, oxygen-sensitive ribonucleoside-triphosphate reductase; pfam03477, ATP-cone, ATP cone domain YP_003445952.1 COG1136, SalX, ABC-type antimicrobial peptide transport system, ATPase component YP_003445955.1 COG0845, efflux transporter YP_003445956.1 COG1136, ABC-type antimicrobial peptide transport system, ATPase component YP_003445957.1 COG0577, ABC-type antimicrobial peptide transport system, permease component YP_003445959.1 COG4989, predicted oxidoreductase YP_003445961.1 pfam00106, adh_short, short chain dehydrogenase; COG1028, FabG YP_003445963.1 COG1247, sortase and related acyltransferases YP_003445964.1 COG1437, CyaB, adenylate cyclase YP_003445967.1 transcriptional regulatory protein YP_003445968.1 Sensor protein CiaH histidine kinase YP_003445970.1 COG0826, collagenase and related proteases YP_003445971.1 COG1199, DinG, Rad3-related DNA helicases YP_003445972.1 pfam01098, FTSW_RODA_SPOVE, cell cycle protein YP_003445973.1 intracellular protease/amidase YP_003445974.1 COG2826, IS30 family YP_003445975.1 COG0546, Gph, predicted phosphatase YP_003445977.1 COG4477, EzrA YP_003445978.1 pfam00583, Acetyltransf_1, acetyltransferase (GNAT) family YP_003445980.1 pfam00293, NUDIX; COG0494, MutT YP_003445983.1 COG0765, HisM, ABC-type amino acid transport system, permease component YP_003445984.1 COG1126, GlnQ, ABC-type polar amino acid transport system, ATPase component YP_003445985.1 COG0190, FolD, 5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase YP_003445987.1 COG0063, predicted sugar kinase YP_003445990.1 COG1015 YP_003445993.1 COG0038 YP_003445994.1 COG0518, GuaA, GMP synthase - glutamine amidotransferase domain YP_003445995.1 COG0813 YP_003445999.1 COG1072, CoaA YP_003446003.1 COG2813, RsmC YP_003446004.1 COG0213, DeoA, thymidine phosphorylase YP_003446005.1 COG0274, DeoC YP_003446007.1 extracellular protein, signal peptide type I YP_003446008.1 COG3845, ABC-type uncharacterized transport system, ATPase components YP_003446009.1 COG4603, COG4603, ABC-type uncharacterized transport system, permease component YP_003446010.1 COG4603, ABC-type uncharacterized transport system, permease component YP_003446011.1 COG0344, predicted membrane protein YP_003446018.1 pfam00583, Acetyltransf_1, acetyltransferase (GNAT) family YP_003446021.1 COG4166, OppA, ABC-type oligopeptide transport system, periplasmic component; pfam00496, SBP_bac_5, bacterial extracellular solute-binding proteins YP_003446024.1 COG1956, COG1956, GAF domain-containing protein YP_003446027.1 COG0396, SufC, ABC-type transport system involved in Fe-S cluster assembly, ATPase component YP_003446029.1 COG0520, SufS-like YP_003446033.1 COG0628, PerM, predicted permease YP_003446035.1 COG0513, SrmB, superfamily II DNA and RNA helicase YP_003446036.1 pfam01408 YP_003446037.1 COG2826, IS30 family YP_003446041.1 COG2826, IS30 family YP_003446042.1 COG0583, LysR YP_003446044.1 COG0564, RluA, pseudouridylate synthases, 23S RNA-specific YP_003446045.1 COG2333, ComEC, predicted hydrolase (metallo-beta-lactamase superfamily) YP_003446046.1 COG2333, ComEC, predicted hydrolase (metallo-beta-lactamase superfamily) YP_003446053.1 COG0313 YP_003446054.1 COG0270, Dcm YP_003446056.1 COG0270, Dcm YP_003446060.1 COG1206 YP_003446065.1 COG1702, PhoH, predicted ATPase YP_003446066.1 COG1670 YP_003446069.1 COG1131, CcmA, ABC-type multidrug transport system, ATPase component YP_003446074.1 COG0346, GloA, lactoylglutathione lyase and related lyases YP_003446075.1 COG2826, IS30 family YP_003446078.1 COG5263, glucan-binding domain (YG repeat) YP_003446091.1 LPXTG motif YP_003446094.1 COG4122, predicted O-methyltransferase YP_003446095.1 Parvulin-like peptidyl-prolyl isomerase (posttranslational modification, protein turnover, chaperones), lipoprotein YP_003446098.1 COG2826, IS30 family YP_003446099.1 COG2826, IS30 family YP_003446100.1 COG2984, ABC-type uncharacterized transport system YP_003446101.1 COG4120, ABC-type uncharacterized transport system, permease component YP_003446102.1 COG1101, ABC-type uncharacterized transport system, ATPase component YP_003446108.1 COG1983, PspC YP_003446110.1 COG0536, Obg, predicted GTPase YP_003446114.1 LPXTG motif YP_003446121.1 COG2116, FocA YP_003446129.1 COG1189, predicted rRNA methylase YP_003446130.1 COG1438, ArgR family protein YP_003446134.1 COG1762, PtsN, mannitol/fructose-specific IIA domain YP_003446135.1 COG3414, SgaB, galactitol-specific IIB YP_003446136.1 COG3775, GatC, galactitol-specific IIC component YP_003446137.1 COG2017, GalM, galactose mutarotase and related enzymes YP_003446142.1 COG0698, RpiB, ribose 5-phosphate isomerase RpiB YP_003446143.1 COG0698, RpiB, ribose 5-phosphate isomerase RpiB YP_003446144.1 COG1959, predicted transcriptional regulator YP_003446161.1 COG2376, DAK1, dihydroxyacetone kinase YP_003446163.1 COG2376, DAK1 YP_003446164.1 COG2376, DAK1 YP_003446166.1 COG1011 YP_003446168.1 7,8-dihydro-8-oxoguanine-triphosphatase; 8-oxo-dGTPase; dGTP pyrophosphohydrolase YP_003446170.1 COG0534, NorM YP_003446171.1 cd00798, INT_XerDC, XerD and XerC integrases YP_003446174.1 COG0164, RnhB, ribonuclease HII YP_003446175.1 COG1161, predicted GTPases YP_003446176.1 LPXTG motif YP_003446178.1 COG1074, RecB, ATP-dependent exoDNAse, beta subunit, (contains helicase and exonuclease domains) YP_003446179.1 COG3857, AddB, ATP-dependent nuclease YP_003446180.1 COG2826, IS30 family YP_003446181.1 COG0561, Cof, predicted hydrolases of the HAD superfamily YP_003446182.1 COG1131, CcmA, ABC-type multidrug transport system, ATPase component YP_003446184.1 COG0642, signal transduction histidine kinase YP_003446185.1 COG0745, OmpR, response regulator YP_003446186.1 cd02432, Nodulin-21_like_1 YP_003446187.1 pfam02687, FtsX, predicted permease YP_003446188.1 COG1136, ABC-type antimicrobial peptide transport system, ATPase component YP_003446191.1 COG1983, stress-responsive transcriptional regulator YP_003446193.1 COG2183, Tex, transcriptional accessory protein YP_003446196.1 COG0701, predicted permease YP_003446197.1 COG3689, predicted membrane protein YP_003446199.1 COG2826, IS30 family YP_003446202.1 COG0210, UvrD, superfamily I DNA and RNA helicases YP_003446204.1 COG0542, ClpA, ATPases with chaperone activity, ATP-binding subunit YP_003446206.1 COG2378, predicted transcriptional regulator YP_003446207.1 fam07693, KAP_NTPase, KAP family P-loop domain. YP_003446208.1 COG0560, SerB, phosphoserine phosphatase YP_003446209.1 COG0317, SpoT, guanosine polyphosphate pyrophosphohydrolase/synthetase YP_003446213.1 pfam06414, Zeta toxin YP_003446214.1 pfam01381, Helix-turn-helix YP_003446217.1 pfam00781, diacylglycerol kinase catalytic domain YP_003446218.1 pfam03747, ADP-ribosylglycohydrolase YP_003446219.1 COG0596, predicted hydrolases or acyltransferases YP_003446220.1 COG4912, predicted DNA alkylation repair enzyme YP_003446222.1 COG3340, peptidase E YP_003446223.1 pfam00583, acetyltransferase (GNAT) family YP_003446231.1 COG2265, SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase YP_003446232.1 COG4086, excreted protein, signal peptide type I YP_003446233.1 PECACE domain YP_003446236.1 pfam00583, acetyltransferase (GNAT) family YP_003446237.1 COG0009, translation factor (SUA5) YP_003446240.1 pfam00583, acetyltransferase (GNAT) family YP_003446246.1 COG4708, predicted membrane protein YP_003446248.1 pfam01741 YP_003446251.1 COG3344, retron-type reverse transcriptase YP_003446252.1 surface protein YP_003446253.1 similar to histidine triad protein of group A streptococci YP_003446254.1 These proteins have been shown to function in the ABC uptake of Zn2+ and Mn2+ and in competence for genetic transformation and adhesion, signal peptide type I, excreted protein YP_003446255.1 COG0531 YP_003446256.1 COG0526, thiol-disulfide isomerase and thioredoxins YP_003446257.1 COG0785 YP_003446258.1 COG3293 YP_003446260.1 COG0785 YP_003446261.1 pfam00216, bacterial DNA-binding protein YP_003446262.1 COG1307, uncharacterized protein, DegV family YP_003446263.1 COG1284 YP_003446264.1 COG0196, FAD synthase YP_003446266.1 COG4109, predicted transcriptional regulator containing CBS domains YP_003446267.1 COG1670, acetyltransferases, including N-acetylases of ribosomal proteins YP_003446269.1 COG2826, IS30 family YP_003446271.1 COG5506, uncharacterized YP_003446275.1 COG0448, glucose-1-phosphate adenylyltransferase YP_003446278.1 COG2826, IS30 family YP_003446282.1 cd00093, helix-turn-helix XRE-family YP_003446283.1 COG0488, ATPase components of ABC transporters with duplicated ATPase domains YP_003446286.1 pfam00753, metallo-beta-lactamase superfamily YP_003446287.1 COG5002, VicK, signal transduction histidine kinase YP_003446288.1 COG0745, response regulator, OmpR family YP_003446289.1 COG1194 YP_003446290.1 COG0280 YP_003446291.1 COG0564, RluA, pseudouridylate synthases, 23S RNA-specific YP_003446292.1 COG0061 YP_003446294.1 COG4116, uncharacterized protein YP_003446296.1 COG1104, cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes YP_003446299.1 COG2344, AT-rich DNA-binding protein YP_003446300.1 COG2071 YP_003446301.1 COG2003 YP_003446304.1 pfam04127, DNA / pantothenate metabolism flavoprotein YP_003446305.1 COG0452, phosphopantothenoylcysteine synthetase/decarboxylase YP_003446306.1 COG4684 YP_003446308.1 pfam02829, 3H domain, three histidine residues YP_003446309.1 COG1051, ADP-ribose pyrophosphatase YP_003446310.1 pfam00583, acetyltransferase (GNAT) family YP_003446311.1 COG1670 YP_003446313.1 pfam02517, CAAX amino terminal protease family YP_003446314.1 COG0765 YP_003446315.1 COG1126 YP_003446317.1 COG0552, signal recognition particle GTPase YP_003446318.1 COG0561, predicted hydrolases of the HAD superfamily YP_003446319.1 COG0561, predicted hydrolases of the HAD superfamily YP_003446320.1 pfam02483 YP_003446323.1 COG0009, translation factor YP_003446326.1 pfam06961 YP_003446329.1 pfam04237 YP_003446331.1 COG2832 YP_003446333.1 COG0758, predicted Rossmann fold nucleotide-binding protein involved in DNA uptake, Smf family YP_003446337.1 COG1063, threonine dehydrogenase and related Zn-dependent dehydrogenases YP_003446338.1 COG1211 YP_003446339.1 COG2244, Membrane protein involved in the export of O-antigen and teichoic acid YP_003446340.1 pfam04991 YP_003446341.1 pfam04991 YP_003446342.1 COG1914, Mn2+ and Fe2+ transporters, NRAMP family YP_003446346.1 COG2065 YP_003446348.1 pfam02620 YP_003446350.1 COG0488, ATPase components of ABC transporters with duplicated ATPase domains YP_003446351.1 COG0501, Zn-dependent protease with chaperone function YP_003446352.1 pfam04011 YP_003446353.1 COG0357, predicted S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division YP_003446357.1 pfam04851 YP_003446359.1 COG2189 YP_003446361.1 cd00079 YP_003446362.1 COG0541, signal recognition particle GTPase YP_003446363.1 pfam04297, helix-turn-helix protein YP_003446364.1 COG4506 YP_003446365.1 COG1078, phosphohydrolase, HD superfamily YP_003446366.1 COG0561, predicted hydrolase, HAD superfamily YP_003446367.1 COG2211, Na+/melibiose symporter and related transporters YP_003446368.1 COG1437, adenylate cyclase, class 2 YP_003446369.1 cd00093, Helix-turn-helix, XRE-family-like YP_003446370.1 cd01189, phiLC3 phage and phage-related integrases YP_003446371.1 COG2361 YP_003446372.1 COG1669, nucleotidyltransferase domain YP_003446373.1 COG3077, DNA-damage-inducible protein, RelB domain YP_003446375.1 COG0239, integral membrane protein possibly involved in chromosome condensation YP_003446376.1 COG0239, Integral membrane protein possibly involved in chromosome condensation YP_003446377.1 COG1605, Chorismate mutase YP_003446378.1 COG0716 YP_003446379.1 COG0618, Exopolyphosphatase-related protein, DHH family YP_003446384.1 pfam00902 YP_003446385.1 COG0672, high-affinity Fe2+/Pb2+ permease, membrane protein YP_003446386.1 COG2837, predicted iron-dependent peroxidase, twin arginine translocation signal peptide YP_003446387.1 COG2822 YP_003446388.1 pfam00239, resolvase, N terminal domain YP_003446389.1 COG5263, glucan-binding domain (YG repeat) YP_003446392.1 COG0718 YP_003446393.1 COG4781, Membrane domain of membrane-anchored glycerophosphoryl diester phosphodiesterase YP_003446398.1 pfam00293, NUDIX domain YP_003446400.1 COG3757, lyzozyme M1 (1,4-beta-N-acetylmuramidase) YP_003446401.1 COG2035, predicted membrane protein YP_003446402.1 pfam04073, prolyl-tRNA synthetases associated domain YP_003446405.1 COG0834 YP_003446406.1 COG1126 YP_003446407.1 COG0765 YP_003446408.1 cd00189, tetratricopeptide repeat domain YP_003446409.1 COG0628, predicted permease YP_003446410.1 COG4166, OppA, ABC-type oligopeptide transport system YP_003446411.1 COG2826, IS30 family YP_003446413.1 COG3464 YP_003446414.1 LPXTG motif YP_003446415.1 COG2826, IS30 family YP_003446424.1 pfam01136, peptidase family U32 YP_003446425.1 LPXTG motif YP_003446426.1 COG3593, predicted ATP-dependent endonuclease of the OLD family YP_003446427.1 COG0210, superfamily I DNA and RNA helicase YP_003446428.1 pfam06125 YP_003446429.1 pfam06125 YP_003446431.1 pfam01580, FtsK/SpoIIIE family YP_003446432.1 COG2946, phage replication protein, helix-turn-helix YP_003446435.1 pfam07275, antirestriction protein (ArdA) YP_003446438.1 COG0433, predicted ATPase YP_003446439.1 pfam01490 YP_003446440.1 pfam00877, NlpC/P60 family, PECACE domain YP_003446442.1 COG0480, ribosomal protection YP_003446444.1 pfam01381, Helix-turn-helix YP_003446446.1 COG1595, DNA-directed RNA polymerase specialized sigma, sigma24 homolog YP_003446449.1 cd01189, phiLC3 phage and phage-related integrases YP_003446451.1 COG2188, transcriptional regulator, PhnF family YP_003446452.1 pfam00892, Integral membrane protein YP_003446453.1 pfam00144, beta-lactamase YP_003446455.1 cd00333, Major intrinsic protein (MIP) superfamily YP_003446456.1 COG5263, glucan-binding domain (YG repeat) YP_003446457.1 cd00093, Helix-turn-helix, XRE-family-like YP_003446460.1 COG2819, predicted hydrolase of the alpha/beta superfamily YP_003446461.1 COG0301, thiamine biosynthesis ATP pyrophosphatase YP_003446462.1 COG1104, cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes YP_003446464.1 COG1674, DNA segregation ATPase YP_003446467.1 COG1349, transcriptional regulator of sugar metabolism YP_003446468.1 COG3666 YP_003446469.1 membrane bound lipoprotein YP_003446470.1 COG2963 YP_003446471.1 pfam00665 YP_003446472.1 similar to S. pneumoniae bacteriophage EJ-1 YP_003446473.1 COG2932, predicted transcriptional regulator YP_003446475.1 similar to orf203 of S. thermophilus bacteriophage Sfi21, immunity region YP_003446476.1 COG2755, lysophospholipase L1 and related esterases YP_003446477.1 COG0561, predicted hydrolase, HAD superfamily YP_003446478.1 COG2843, enzyme of poly-gamma-glutamate biosynthesis YP_003446483.1 COG1126, ABC-type polar amino acid transport system, ATPase component YP_003446484.1 COG0765, ABC-type amino acid transport system, permease component YP_003446485.1 cd03036 YP_003446489.1 COG1272 YP_003446490.1 COG0311 YP_003446491.1 COG0214 YP_003446494.1 COG0431, predicted flavoprotein YP_003446495.1 COG2461, uncharacterized YP_003446496.1 pfam05979, bacterial protein of unknown function YP_003446500.1 LPXTG motif; pfam00082, subtilase family YP_003446504.1 COG0513, DNA and RNA helicase, superfamily II YP_003446505.1 COG3568, metal-dependent hydrolase YP_003446507.1 COG2826, IS30 family YP_003446511.1 COG2826, IS30 family YP_003446512.1 d04585, CBS pair ACT assoc2, this cd contains two tandem repeats of the cystathionin YP_003446521.1 COG2826, IS30 family YP_003446523.1 COG1309, AcrR family YP_003446524.1 COG1307, uncharacterized protein in bacteria, DegV family YP_003446525.1 COG2081 YP_003446527.1 cd01106, Helix-turn-helix transcription regulator YP_003446528.1 COG0733, SNF family YP_003446531.1 COG1132, ABC-type multidrug transport system, ATPase and permease components YP_003446534.1 COG0474, Cation transport ATPase YP_003446535.1 COG4633, uncharacterized protein in bacteria YP_003446536.1 COG3682 YP_003446538.1 COG0765 YP_003446539.1 COG0765 YP_003446540.1 COG1126 YP_003446541.1 COG0834 YP_003446542.1 COG1131, ABC-type multidrug transport system, ATPase component YP_003446546.1 excreted protein, signal peptide type I YP_003446547.1 COG0461 YP_003446548.1 COG0284 YP_003446549.1 COG1589, ftsQ protein YP_003446550.1 COG0707 YP_003446551.1 COG0771 YP_003446554.1 COG3464 YP_003446555.1 COG1217 YP_003446556.1 COG1187, 16S_rRNA pseudouridylate synthase and related pseudouridylate synthases YP_003446557.1 COG0607 YP_003446559.1 COG2197, response regulator of regulon involved in salavaricin-like lantibiotics YP_003446560.1 COG4585, histidine kinase of regulon involved in salavaricin-like lantibiotics YP_003446561.1 ABC-type antimicrobial peptide transport system YP_003446562.1 COG1136 YP_003446563.1 COG0583, regulation of capsule expression YP_003446565.1 COG0464 YP_003446569.1 COG5263, glucan binding domain (YG repeat) YP_003446572.1 COG1396 YP_003446573.1 COG0300, DltE, short-chain dehydrogenases of various substrate specificities YP_003446574.1 COG1234, ElaC, metal-dependent hydrolases of the beta-lactamase superfamily III YP_003446576.1 COG2262, predicted GTPase YP_003446577.1 COG0324 YP_003446580.1 COG1940 YP_003446581.1 COG5263, glucan binding domain (YG repeat), Excalibur-domain for Ca++-binding YP_003446584.1 LPXTG motif YP_003446586.1 COG2972 YP_003446587.1 COG4753 YP_003446589.1 COG2143, thioredoxin-related protein YP_003446590.1 COG0785 YP_003446592.1 COG1670 YP_003446593.1 unknown EC_number=6.3._._; COG0171 YP_003446594.1 unknown EC_number=2.4.2._.; COG1488 YP_003446596.1 COG1476, COG1476, predicted transcriptional regulators YP_003446599.1 COG113 YP_003446600.1 COG0782 YP_003446601.1 COG1559, predicted solute-binding protein YP_003446602.1 COG0456 YP_003446603.1 COG3153 YP_003446604.1 COG0773 YP_003446606.1 COG0553 YP_003446607.1 COG4823, related to Lactocuccus lactis abiD YP_003446609.1 COG1168 YP_003446612.1 COG4166 YP_003446613.1 COG2244 YP_003446614.1 COG0769 YP_003446618.1 COG1227 YP_003446619.1 COG2827, predicted endonuclease containing a URI domain YP_003446620.1 COG4123, O-methyltransferase YP_003446621.1 COG1098 YP_003446622.1 COG056 YP_003446624.1 COG0629 YP_003446626.1 COG2826, IS30 family YP_003446627.1 COG0017 YP_003446628.1 COG0346 YP_003446632.1 COG0431, COG0431, predicted flavoprotein YP_003446633.1 LPXTG motif; G5 domain family protein, collagen-like YP_003446635.1 COG3022 YP_003446636.1 LPXTG motif YP_003446637.1 COG3464 YP_003446638.1 pfam 02371, COG3547 YP_003446639.1 COG3525, LPXTG motif YP_003446640.1 LPXTG motif YP_003446641.1 COG3022 YP_003446645.1 COG0474 YP_003446646.1 COG0053 YP_003446647.1 COG0488 YP_003446648.1 COG0617 YP_003446649.1 COG0289 YP_003446652.1 COG1109 YP_003446653.1 COG4856 YP_003446655.1 COG0492 YP_003446656.1 COG1481 YP_003446658.1 COG1660 YP_003446660.1 COG0218, GTP-binding protein YP_003446661.1 COG1219 YP_003446663.1 COG0262 YP_003446664.1 COG0783 YP_003446665.1 COG5263, COG3757 YP_003446666.1 COG0149 YP_003446669.1 COG0503 YP_003446670.1 pfam08241, methyltransf_11, methyltransferase domain. YP_003446671.1 COG0081 YP_003446672.1 COG0080 YP_003446673.1 penicillin-insensitive metallo-DD-carboxypeptidase YP_003446674.1 COG0537 YP_003446675.1 COG1363, FrvX, cellulase M and related proteins YP_003446676.1 COG1114 YP_003446678.1 COG1573 YP_003446680.1 COG0778 YP_003446681.1 COG0834 YP_003446682.1 COG0622, predicted phosphoesterase YP_003446683.1 COG0322 YP_003446684.1 COG5549, predicted Zn-dependent protease YP_003446685.1 COG2348 YP_003446686.1 COG2348 YP_003446687.1 COG0627 YP_003446688.1 COG0595, metallo-beta-lactamase superfamily protein YP_003446689.1 COG0608 YP_003446690.1 COG1126 YP_003446691.1 COG0834, excreted protein, signal peptide type I YP_003446692.1 COG0765 YP_003446693.1 COG0765 YP_003446694.1 COG3839 YP_003446695.1 COG2508, regulator of polyketide synthase expression YP_003446698.1 COG1670, acetyltransferase YP_003446699.1 COG1045 YP_003446700.1 COG1185 YP_003446701.1 COG0685 YP_003446702.1 COG0620 YP_003446703.1 COG3666 YP_003446706.1 COG0610 YP_003446708.1 COG0732 YP_003446710.1 COG3943, virulence protein YP_003446711.1 COG0286 YP_003446716.1 COG1940 YP_003446717.1 COG1263 YP_003446719.1 COG1609 YP_003446720.1 COG1257 YP_003446721.1 COG3425 YP_003446722.1 COG3610 YP_003446723.1 COG2966 YP_003446724.1 COG2815 YP_003446725.1 COG0631 YP_003446726.1 COG0144 YP_003446727.1 COG0223 YP_003446728.1 COG1198 YP_003446729.1 COG1758 YP_003446730.1 COG0194 YP_003446732.1 COG1418 YP_003446734.1 COG1323, predicted nucleotidyltransferase YP_003446735.1 COG0500, SmtA, SAM-dependent methyltransferases YP_003446738.1 COG1713, predicted hydrolase YP_003446739.1 COG1057 YP_003446741.1 COG1161, predicted GTPase YP_003446742.1 COG2179, predicted hydrolase of the HAD superfamily YP_003446743.1 COG0598 YP_003446744.1 COG0668, MscS, small-conductance mechanosensitive channel YP_003446745.1 COG3633 YP_003446751.1 COG0653 YP_003446755.1 COG0201 YP_003446756.1 COG0463 YP_003446757.1 COG1442 YP_003446758.1 COG1442 YP_003446759.1 COG1215, glycosyltransferases YP_003446760.1 COG1442 YP_003446762.1 LbetaH domain YP_003446763.1 COG1442 YP_003446764.1 LPXTG motif YP_003446765.1 COG4108 YP_003446769.1 COG0064 YP_003446771.1 COG0231 YP_003446773.1 COG0781 YP_003446774.1 pfam02517 YP_003446775.1 bacteriocin/pheromone -type, double glycine-cleavage motif YP_003446776.1 COG0825 YP_003446777.1 COG0777 YP_003446778.1 COG0439 YP_003446779.1 COG0764 YP_003446780.1 COG0511 YP_003446781.1 COG0304 YP_003446782.1 COG1028 YP_003446783.1 COG0331 YP_003446784.1 NAD(P)H-dependent flavin oxidoreductase, FMN-binding superfamily domain; cd00415 YP_003446785.1 acyl carrier protein, lipid metabolism / secondary metabolites biosynthesis, transport, and catabolism, COG0236, phosphopantetheine attachment site YP_003446786.1 COG0332 YP_003446787.1 COG1846 YP_003446788.1 COG1024 YP_003446789.1 COG0527 YP_003446791.1 COG0172 YP_003446792.1 COG3464 YP_003446793.1 COG1725 YP_003446795.1 COG3293 YP_003446796.1 excreted protein, signal peptide type I collagen-binding surface protein YP_003446797.1 COG0791, cell wall-associated hydrolases, PECACE domain YP_003446800.1 COG1132 YP_003446806.1 bifunctional AAC YP_003446809.1 COG2378, predicted transcriptional regulator YP_003446813.1 COG2226 YP_003446815.1 COG1961 YP_003446820.1 COG1309 YP_003446823.1 COG1115 YP_003446825.1 COG5263, glucan-binding domain (YG repeat) YP_003446826.1 COG5263, glucan-binding domain (YG repeat) YP_003446829.1 Chaperone, homology to GrpE YP_003446830.1 Chaperone, tetratricopeptide repeat domain, homology to DnaJ YP_003446831.1 Chaperone, homology to DnaK, COG0443 YP_003446833.1 cd00093, HTH_XRE, helix-turn-helix XRE-family like proteins YP_003446834.1 COG1193 YP_003446835.1 COG1286, CvpA, uncharacterized membrane protein YP_003446837.1 COG1039 YP_003446839.1 COG0507 YP_003446840.1 COG0544 YP_003446842.1 COG2197 YP_003446843.1 COG4585 YP_003446844.1 COG4758, membrane protein YP_003446845.1 isopentenyl-diphosphate:dimethylallyl diphosphate isomerase type 2 (IDI-2) FMN-binding domain. Two types of IDIs have been characterized at present. The long known IDI-1 is only dependent on divalent metals for activity, whereas IDI-2 requires a metal, FMN and NADPH. IDI-2 catalyzes the interconversion of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) in the mevalonate pathway YP_003446846.1 COG1577 YP_003446847.1 COG3407 YP_003446848.1 COG1577 YP_003446849.1 COG5263, glucan-binding domain (YG repeat) YP_003446850.1 COG0745, ompR family YP_003446853.1 COG0116, predicted N6-adenine-specific DNA methylase YP_003446856.1 pfam03838, RecU YP_003446858.1 COG4166, ABC-type oligopeptide transport system YP_003446860.1 smart00642, alpha-amylase domain YP_003446863.1 COG3344, retron-type reverse transcriptase YP_003446864.1 COG0542 YP_003446869.1 COG 1476 YP_003446873.1 COG0386 YP_003446876.1 pfam00817 YP_003446877.1 COG2932 YP_003446878.1 COG3104, PTR2, Dipeptide/tripeptide permease, proton-dependent transport YP_003446879.1 COG1373, AAA+ superfamily YP_003446882.1 COG1733 YP_003446883.1 similar to methylenomycin A resistance protein YP_003446885.1 similar to phage integrase familiy YP_003446895.1 cd01189, INT_phiLC3_C, phage-related integrases, site-specific recombinases YP_003446898.1 COG2826, IS30 family YP_003446899.1 COG1668, NatB, ABC-type Na+ efflux pump, quorum sensing regulated YP_003446900.1 COG4555, NatA, ABC-type Na+ transport system, quorum sensing regulated YP_003446906.1 pfam01569, PAP2 superfamily. YP_003446908.1 COG0219, CspR, SpoU family YP_003446909.1 COG0619, CbiQ, ABC-type cobalt transport system YP_003446910.1 COG1122, CbiO, ABC-type cobalt transport system YP_003446913.1 COG0569, TrkA, K+ transport system, NAD-binding component YP_003446914.1 COG0168, TrkG, Trk-type K+ transport system, membrane component YP_003446916.1 COG0389, DinP, nucleotidyltransferase/DNA polymerase involved in DNA repair YP_003446917.1 bacitracin resistance protein YP_003446926.1 COG1461, predicted kinase related to dihydroxyacetone kinase YP_003446929.1 COG2826, IS30 family YP_003446930.1 COG2826, IS30 family YP_003446932.1 pfam04397, LytTr DNA-binding domain. YP_003446933.1 smart00014, acidPPc, acid phosphatase homologues YP_003446934.1 COG1132, MdlB, ABC-type multidrug transport system YP_003446935.1 COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease component YP_003446936.1 pfam01047, MarR family. YP_003446938.1 COG0534, NorM, Na+-driven multidrug efflux pump YP_003446940.1 COG1058, CinA, predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA YP_003446941.1 COG1316, LytR, one TM helix predicted YP_003446942.1 pfam00583, acetyltransferase (GNAT) family YP_003446943.1 COG0802, predicted ATPase or kinase YP_003446948.1 COG1523, pullulanase PulA and related glycosidases, LPXTG motif YP_003446949.1 COG2141, flavin-dependent oxidoreductases YP_003446951.1 pfam00232, glycosyl hydrolase family 1. YP_003446953.1 EEP protein, determinant for enhanced expression of pheromone YP_003446956.1 COG2826, IS30 family YP_003446957.1 COG2826, IS30 family YP_003446962.1 COG2826, IS30 family YP_003446963.1 pfam00583, acetyltransferase (GNAT) family YP_003446964.1 pfam00583, acetyltransferase (GNAT) family YP_003446966.1 Pfam04397, LytTr DNA-binding domain YP_003446967.1 COG0842, multidrug transport system YP_003446968.1 COG1131, CcmA, multidrug transport system YP_003446970.1 COG0406 YP_003446971.1 COG5263, glucan-binding domain (YG repeat) YP_003447003.1 COG2826, IS30 family YP_003447004.1 pfam00485, PRK, phosphoribulokinase / uridine kinase family YP_003447005.1 COG0602, NrdG, organic radical activating enzymes; anaerobic ribonucleoside-triphosphate reductase activator YP_003447006.1 COG3981 YP_003447008.1 COG1328, NrdD, oxygen-sensitive ribonucleoside-triphosphate reductase YP_003447010.1 orf47, induced duriong competence in Streptococcus pneumoniae YP_003447011.1 COG1502, Cls, phosphatidylserine/phosphatidylglycerophosphate/cardiolipi n synthases YP_003447012.1 excreted protein, signal peptide type I YP_003447013.1 COG0285, FolC, folylpolyglutamate synthase, bifunctional protein YP_003447015.1 smart00732 YP_003447017.1 membrane bound lipoprotein YP_003447018.1 COG1393, arsenate reductase and related proteins, glutaredoxin family YP_003447019.1 COG0474, cation transport ATPase YP_003447020.1 COG0006, Xaa-Pro aminopeptidase YP_003447021.1 COG0178, excinuclease ATPase subunit YP_003447022.1 COG0598, Mg2+ and Co2+ transporters, CorA family YP_003447024.1 COG1619, homologs of microcin C7 resistance protein MccF YP_003447025.1 pfam03352, methyladenine glycosylase YP_003447026.1 COG0632, holiday junction resolvasome, DNA-binding subunit YP_003447027.1 COG 0323.1, MutL YP_003447029.1 pfam04397, LytTr DNA-binding domain YP_003447031.1 COG1780, proteins involved in ribonucleotide reduction YP_003447033.1 COG 4753, two component regulatory system, response regulators containing CheY-like receiver domain and AraC-type DNA-binding domain YP_003447034.1 COG2972, sensor histidine kinase, two component regulatory system; signal transduction proteins with a C-terminal ATPase domain YP_003447035.1 COG5578, predicted integral membrane proteins YP_003447037.1 COG 2011, metal ion transport YP_003447038.1 COG1135, metal ion transport system YP_003447039.1 COG0624, acetylornithine deacetylase/succinyl-diaminopimelate desuccinylase /and related deacylases; peptidase family M20. This family includes a range of zinc metallopeptidases belonging to several families in the peptidase classification. Family M20 are glutamate carboxypeptidases. YP_003447040.1 COG1464, ABC-type metal ion transport system YP_003447041.1 pfam00497, bacterial extracellular solute-binding proteins YP_003447042.1 pfam00497, bacterial extracellular solute-binding proteins, duplication of smi_1945 YP_003447043.1 COG4392, membrane protein YP_003447044.1 COG1296, AzlC protein YP_003447045.1 pfam02517 YP_003447046.1 cd00093, Helix-turn-helix XRE-family like proteins. YP_003447047.1 COG0533, QRI7, metal-dependent proteases with possible chaperone activity YP_003447048.1 COG0456 YP_003447049.1 COG1214, inactive homolog of metal-dependent proteases YP_003447050.1 COG2826, IS30 family YP_003447051.1 bacteriocin/pheromone -type, double glycine-cleavage motif YP_003447052.1 bacteriocin/pheromone -type, double glycine-cleavage motif YP_003447056.1 COG0595, predicted hydrolase of the metallo-beta-lactamase superfamily pfam00753 YP_003447057.1 COG0445, GidA, NAD/FAD-utilizing enzyme apparently involved in cell division YP_003447059.1 pfam03054, COG0482, tRNA(5-methylaminomethyl-2-thiouridine)-methyltransferase YP_003447060.1 COG2826, IS30 family YP_003447063.1 COG0165 YP_003447064.1 COG0137 YP_003447065.1 pfam00497, bacterial extracellular solute-binding proteins, family 3 YP_003447066.1 COG1136, antimicrobial peptide transport system, ATPase component YP_003447071.1 membrane spanning protein YP_003447073.1 cd00093, Helix-turn-helix XRE-family like proteins YP_003447074.1 cd00118, LysM, Lysin domain YP_003447075.1 pfam 03315; COG1760 YP_003447076.1 pfam03313; COG1760 YP_003447077.1 COG0637, predicted phosphatase YP_003447078.1 COG1086 YP_003447079.1 pfam00535, Glycos_transf_2 YP_003447080.1 COG2807 YP_003447081.1 COG1695, predicted transcriptional regulators YP_003447082.1 COG4709, predicted membrane protein YP_003447086.1 cd01518, rhodanese homology domain superfamily YP_003447087.1 related to bacteriocin immunity proteins YP_003447088.1 pfam02517 YP_003447090.1 COG0395, UgpE, ABC-type sugar transport system YP_003447091.1 COG1175; ABC-type polysaccharide transport system YP_003447093.1 fam00480, ROK family YP_003447094.1 COG0383, alpha-mannosidase YP_003447098.1 phage-related YP_003447101.1 COG3378, predicted ATPase YP_003447102.1 similar to replication protein Streptococcus thermophilus plasmid YP_003447103.1 phage-related YP_003447104.1 phage-associated protein YP_003447109.1 COG3646, uncharacterized phage-encoded protein YP_003447110.1 COG1476, predicted transcriptional regulator YP_003447111.1 cd00093, helix-turn-helix XRE-family like proteins YP_003447112.1 COG2865, predicted transcriptional regulator containing an HTH domain and an uncharacterized domain shared with the mammalian protein Schlafen YP_003447113.1 cd01189, phiLC3 phage and phage-related integrases, site-specific recombinases YP_003447114.1 COG3537, alpha-1,2-mannosidase YP_003447115.1 COG3669, alpha-L-fucosidase YP_003447117.1 COG3250 YP_003447119.1 COG2503, predicted secreted acid phosphatase, signal peptide type I YP_003447120.1 cd01017, metal binding protein AcdA YP_003447121.1 COG1108, ABC-type Mn2+/Zn2+ transport systems YP_003447122.1 COG1121, ABC-type Mn/Zn transport, ATPase component YP_003447123.1 pfam01047, MarR family YP_003447124.1 facilitates D-alanine ligation to DCP by binding Dcl and Dcp YP_003447126.1 involved in D-alanine export YP_003447127.1 D-alanine-activating enzyme YP_003447129.1 cd00333, major intrinsic protein (MIP) superfamily YP_003447130.1 COG0578 YP_003447131.1 COG0554 YP_003447133.1 cd00498, Hsp33, heat shock protein 33 (Hsp33) YP_003447134.1 COG0042 YP_003447139.1 COG3201, PnuC YP_003447140.1 COG3172, NadR, predicted ATPase/kinase involved in NAD metabolism YP_003447141.1 COG0542, ClpA, ATPases with chaperone activity, ATP-binding subunit YP_003447142.1 pfam05848, firmicute transcriptional repressor of class III stress genes (CtsR) YP_003447143.1 COG1116, TauB, ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component YP_003447144.1 COG0715, TauA, ABC-type nitrate/sulfonate/bicarbonate transport systems YP_003447145.1 COG0600, TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component YP_003447147.1 COG5263, glucan-binding domain (YG repeat); pfam05257, CHAP domain. This domain corresponds to an amidase function YP_003447149.1 COG0305 YP_003447151.1 COG3887, protein containing a modified GGDEF domain and a DHH domain YP_003447152.1 COG1544, ribosome-associated protein Y YP_003447153.1 COG1040, predicted amidophosphoribosyltransferases, involved in transformation YP_003447154.1 COG4098, superfamily II DNA/RNA helicase required for DNA uptake YP_003447156.1 COG0031 YP_003447157.1 pfam00889, elongation factor TS YP_003447159.1 pfam05257, CHAP domain. This domain corresponds to an amidase function YP_003447160.1 COG2891 YP_003447161.1 COG1792 YP_003447162.1 COG0619, ABC-type cobalt transport system, permease component YP_003447163.1 COG1122, ABC-type cobalt transport system, ATPase component YP_003447164.1 COG1122, ABC-type cobalt transport system, ATPase component YP_003447165.1 COG0558, PgsA YP_003447167.1 COG0612, predicted Zn-dependent peptidases YP_003447168.1 COG0612, predicted Zn-dependent peptidases YP_003447170.1 COG1195, recombinational DNA repair YP_003447171.1 pfam00478, IMPDH, IMP dehydrogenase / GMP reductase domain YP_003447172.1 COG0180, tryptophanyl-tRNA synthetase YP_003447173.1 COG0488, ATPase components of ABC transporters with duplicated ATPase domains YP_003447175.1 membrane protein YP_003447177.1 comE, competence-specific YP_003447178.1 comD, competence-specific YP_003447181.1 COG0265, trypsin-like serine proteases YP_003447182.1 parB family, similar to spoOJ