-- dump date 20140620_083621 -- class Genbank::CDS -- table cds_note -- id note YP_004325075.1 S4 domain protein; ribosome-associated heat shock protein implicated in the recycling of the 50S subunit YP_004325076.1 septum formation initiator family protein YP_004325078.1 beta-lactamase class A YP_004325082.1 gene fragment YP_004325087.1 COG1066 YP_004325088.1 beta_CA_cladeD, carbonic anhydrases (CA) are zinc-containing enzymes YP_004325092.1 Aspartate/tyrosine/aromatic aminotransferase COG04364 YP_004325094.1 Phosphate acetyl/butaryl transferase; cl00390 YP_004325099.1 competence factor transport YP_004325106.1 pfam00583, acetyltransferase (GNAT) family YP_004325112.1 AIPR protein This family of proteins was identified in as an abortive infection phage resistance protein often found in restriction modification system operons, pfam 10592 YP_004325114.1 LPXTG motif, YSIRK type signal peptide; pfam04650; Glycosyl hydrolase family 20 (GH20) catalytic domain of dispersin B (DspB), lacto-N-biosidase (LnbB) and related proteins. Dispersin B is a soluble beta-N-acetylglucosamidase found in bacteria that hydrolyzes the beta-1,6-linkages of PGA YP_004325115.1 transcriptional regulator, GntR family protein YP_004325135.1 SPX domain-containing protein involved in vacuolar polyphosphate accumulation YP_004325137.1 truncation, gene fragment with homology to C-terminus of a 381 aa protein from Streptococcus sanguinis SK36 YP_004325143.1 COG0168, TrkH, Trk-type K+ transport system,membrane component YP_004325144.1 TrkA-N domain protein YP_004325145.1 LPXTG motif, ribonuclease E domain, N-terminal YP_004325146.1 homologous to S. pneumoniae TCS08 YP_004325147.1 homologous to S. pneumoniae TCS08 YP_004325169.1 positive transcriptional regulator of glucosyltransferase and Spp phenotype YP_004325188.1 N-succinyl-L,L-diaminopimelic acid desuccinylase YP_004325195.1 COG2071 YP_004325202.1 putative phosphoglycolate phosphatase YP_004325207.1 COG0343 YP_004325208.1 COG1835, diverse family of lipases and esterases,predicted acyltransferases [Lipid metabolism] YP_004325211.1 involved in competence YP_004325212.1 involved in competence YP_004325213.1 involved in competence YP_004325214.1 involved in competence YP_004325215.1 involved in competence YP_004325216.1 involved in competence YP_004325219.1 COG0827, Adenine-specific DNA methylase [DNA replication, recombination, and repair] YP_004325222.1 COG0706, intracellular trafficking and secretion YP_004325223.1 COG1847 YP_004325229.1 iron-containing YP_004325230.1 plasmin receptor in S. pneumoniae; COG0057; [Carbohydrate metabolism]; NADB_Rossmann: Rossmann-fold NAD(P)(+)-binding proteins YP_004325231.1 COG0564, Pseudouridylate synthases, 23S RNA-specific YP_004325236.1 involved in late competence gene transcriptional activation YP_004325239.1 COG2378, predicted transcriptional regulator YP_004325244.1 transglycosylase associated protein YP_004325245.1 COG1187; 16S rRNA pseudouridylate synthase and related pseudouridylate synthases YP_004325251.1 Cof family protein YP_004325255.1 COG0285, bifunctional folylpolyglutamate synthase/ dihydrofolate synthase, [Coenzyme metabolism]; Mur ligase family, glutamate ligase domain YP_004325257.1 Dihydroneopterinaldolase;2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase YP_004325262.1 Cof family protein YP_004325263.1 universal stress protein family, putative YP_004325267.1 COG0531 YP_004325270.1 COG1658, Small primase-like proteins, TOPRIM,Topoisomerase-primase domain. This is a nucleotidyl transferase/hydrolase domain YP_004325274.1 Glutamine-rich domain; predicted C-terminal membrane helix (TM-helix: 251-268)N-terminus outside YP_004325279.1 COG1322, predicted nuclease of restriction endonuclease-like fold, RmuC family YP_004325281.1 COG0503, Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins YP_004325284.1 COG0706I, intracellular trafficking and secretion YP_004325296.1 COG1253 YP_004325302.1 Trk-type K+ transport systems, membrane components [Inorganic ion transport and metabolism] YP_004325303.1 putative cation transport protein, NAD-binding component YP_004325304.1 COG0219 YP_004325307.1 pfam01569, PAP2 superfamily YP_004325311.1 COG4555, quorum sensing regulated YP_004325312.1 COG1668, quorum sensing regulated YP_004325324.1 NAD binding YP_004325339.1 ESAT-6 secretion Pathway YP_004325347.1 acetyltransferase, GNAT family, putative YP_004325350.1 COG0419; Walker motif YP_004325351.1 COG2932 YP_004325352.1 pfam00817 YP_004325365.1 COG 1476 YP_004325370.1 LPXTG motif, Fibronectin type-III domain profile,YSIRK signal peptide YP_004325373.1 COG0796 YP_004325375.1 Protein phosphatase 2A homologues, catalytic domain. Large family of serine/threonine phosphatases,including PP1, PP2A and PP2B (calcineurin) family members. YP_004325380.1 COG1187 YP_004325382.1 Raw: 11.18 YP_004325383.1 uviB bacteriocin-like, putative YP_004325387.1 N-terminal HTH motif, transcriptional regulator,putative YP_004325389.1 LPXTG motif, sspA homologue YP_004325393.1 LPXTG motif YP_004325404.1 Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family YP_004325405.1 COG0220 YP_004325407.1 COG0195 YP_004325417.1 COG1204, superfamily II helicase YP_004325418.1 COG1670 YP_004325419.1 COG1112 YP_004325420.1 COG0525 YP_004325426.1 COG0526 YP_004325433.1 COG3557 YP_004325443.1 Lipid A core - O-antigen ligase and related enzymes [Cell envelope biogenesis, outer membrane] YP_004325445.1 putative C-terminal truncation YP_004325449.1 CbiQ type superfamily, cobalt transport system,putative YP_004325451.1 CbiO_domain YP_004325453.1 plasmid associated, truncation YP_004325454.1 plasmid associated, truncation YP_004325455.1 plasmid replication protein-like protein YP_004325457.1 truncation YP_004325458.1 N-terminal truncation YP_004325464.1 PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold YP_004325470.1 COG2323 YP_004325473.1 sugar transferase involved in lipopolysaccharide synthesis, putative YP_004325475.1 putative xenolog, frameshift YP_004325476.1 putative xenolog, frameshift YP_004325485.1 type II secretory pathway YP_004325486.1 COG1670, acetyltransferases, including N-acetylases of ribosomal proteins YP_004325497.1 COG0604 YP_004325498.1 COG1959 YP_004325522.1 COG0780 YP_004325523.1 7-cyano-7-deazaguanosine (preQ0) biosynthesis protein, putative YP_004325524.1 COG0720 YP_004325525.1 Queosin biosynthesis, putative YP_004325529.1 COG1380 YP_004325530.1 The two products of the lrgAB operon are potential membrane proteins, and LrgA and LrgB are both thought to control of murein hydrolase activity and penicillin tolerance YP_004325531.1 ABC transporter domain, putative YP_004325534.1 ATP cone domain superfamily YP_004325535.1 COG3611 YP_004325543.1 COG0653 YP_004325544.1 possibly phe sensitive YP_004325545.1 possibly tyr-sensitive YP_004325546.1 COG073 YP_004325551.1 cell wall surface anchor family protein, LPXTG motif YP_004325561.1 transcriptional regulator, ROK family protein YP_004325576.1 gene fragment, putative YP_004325583.1 PLP (PyridoxaL 5'-phosphatedependent) enzymes class III (PLPDE_III) YP_004325587.1 truncation, gene fragment encoding the amino-terminus of a DivIVA like protein YP_004325599.1 predicted permease, ion transport YP_004325618.1 COG1660 YP_004325620.1 COG1481 YP_004325621.1 COG0492 YP_004325623.1 COG4856 YP_004325627.1 COG0289 YP_004325628.1 COG0617 YP_004325629.1 COG0488 YP_004325631.1 COG0053 YP_004325643.1 COG0017 YP_004325645.1 COG0629 YP_004325654.1 contains ribosomal protein S1 domain YP_004325662.1 COG0769 YP_004325663.1 COG2244 YP_004325681.1 EC_number 2.4.2._, UNKNOWN YP_004325682.1 COG0171 YP_004325691.1 COG5263, Glucan-binding domain (YG repeat), 40mer repeat YP_004325692.1 COG1940 YP_004325701.1 short-chain dehydrogenases of various substrate specificities YP_004325702.1 cell wall surface anchor family protein, LPXTG motif, YSIRK type signal peptide, G5 domain YP_004325710.1 COG0025 YP_004325714.1 LPXTG motif, surface-associated CshA-like fibrillar surface protein YP_004325725.1 COG0647 YP_004325737.1 putative extracellular amino acid-binding protein YP_004325748.1 truncation YP_004325763.1 required for phosphorylcholine incorporation in teichoic and lipoteichoic acids YP_004325767.1 gene fragment, truncation; COG5263, Glucan-binding domain (YG repeat) YP_004325781.1 COG0334 YP_004325786.1 Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. YP_004325790.1 cyclophilin_WD40: cyclophilin-type peptidylprolyl cis- trans isomerases YP_004325792.1 COG1837, predicted RNA-binding protein (contains KH domain) YP_004325823.1 5 TM helices YP_004325824.1 5 TM helices YP_004325826.1 5 TM helices YP_004325828.1 5 TM helices YP_004325833.1 GAF domain-containing superfamily protein YP_004325845.1 HU family DNA-binding protein YP_004325866.1 nucleotide-binding protein involved in DNA uptake,Smf family, COG0758, predicted Rossmann fold YP_004325877.1 amino-terminal truncation, putative YP_004325884.1 truncation, putative YP_004325895.1 3 TM helices predicted YP_004325896.1 8 TM helices predicted YP_004325901.1 authentic stop codon YP_004325902.1 authentic stop codon YP_004325908.1 FtsX superfamily YP_004325928.1 flavoprotein involved in panthothenate metabolism YP_004325929.1 flavoprotein involved in panthothenate metabolism YP_004325936.1 COG2071 YP_004325940.1 this family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily YP_004325968.1 enolases are homodimeric enzymes that catalyse the reversible dehydration of 2-phospho-D-glycerate to phosphoenolpyruvate as part of the glycolytic and gluconeogenesis pathways YP_004325972.1 putative exopolysaccharide biosynthesis protein related to N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase YP_004325976.1 putative relaxase/mobilisation protein; internal deletion YP_004325978.1 this family includes the AlwI (recognises GGATC),Bsp6I (recognises GC^NGC), BstNBI (recognises GASTC),PleI(recognises GAGTC) and MlyI (recognises GAGTC) restriction endonucleases YP_004325988.1 Thiamine pyrophosphate (TPP) dependent dehydrogenase family protein YP_004326001.1 COG0038 YP_004326002.1 COG0164 YP_004326003.1 COG1161 YP_004326005.1 PemK superfamily protein YP_004326008.1 COG3857 YP_004326015.1 pyridoxal-dependent decarboxylase, C-terminal sheet domain YP_004326018.1 This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily YP_004326025.1 pfam00781 YP_004326026.1 2 TM helices predicted YP_004326027.1 2 TM helices predicted YP_004326029.1 1 TM helix predicted YP_004326040.1 truncation, putative YP_004326042.1 COG0596 YP_004326047.1 N-terminal truncation, frameshift YP_004326048.1 PECACE domain protein YP_004326052.1 Sua5/YciO/YrdC/YwlC family protein YP_004326062.1 pfam01741 YP_004326068.1 gene fusion, putative YP_004326070.1 surface protein, putative YP_004326071.1 C-terminal truncation YP_004326096.1 COG1063, Threonine dehydrogenase and related Zn-dependent dehydrogenases YP_004326106.1 COG3757 YP_004326107.1 predicted integral membrane protein, 8 TM helices YP_004326111.1 COG0834 YP_004326112.1 COG1126 YP_004326113.1 COG0765 YP_004326116.1 9 TM helices predicted YP_004326131.1 membrane protein, 10 TM helices predicted YP_004326136.1 putative helix-turn-helix protein YP_004326138.1 membrane protein, 8 TM helices predicted YP_004326143.1 cytoplasmic protein, hotdog fold domain YP_004326165.1 peptidylprolyl isomerase, parvulin-like peptidyl-prolyl isomerase (Posttranslational modification,protein turnover, chaperones), lipoprotein YP_004326171.1 Transfer-messenger RNA (tmRNA, 10Sa RNA, ssrA) is bacterial RNA having both tRNA and mRNA properties and playing an essential role in recycling of 70S ribosomes that are stalled on defective mRNA YP_004326181.1 fibronectin binding YP_004326190.1 4 TM helices predicted YP_004326202.1 COG5263, Glucan-binding domain (YG repeat) YP_004326207.1 Hsp70/DnaK superfamily YP_004326220.1 NAD(FAD)-utilizing enzyme possibly involved in translation YP_004326235.1 membrane protein, 6 TM helices predicted YP_004326241.1 frameshift, putative YP_004326242.1 frameshift, putative YP_004326248.1 membrane protein, 3 TM helices predicted YP_004326264.1 SMI1 / KNR4 family, putative; proteins in this family are involved in the regulation of 1,3-beta-glucan synthase activity and cell-wall formation YP_004326273.1 4 TM helices predicted; integral membrane protein possibly involved in chromosome condensation YP_004326274.1 4 TM helices predicted; integral membrane protein possibly involved in chromosome condensation YP_004326277.1 it is predicted that this family of proteins all perform a phosphoesterase function, including the single stranded DNA exonuclease RecJ YP_004326280.1 frameshift, putative YP_004326281.1 frameshift, putative YP_004326291.1 Zn-dependent protease with chaperone function YP_004326305.1 DNA translocase, cell division protein YP_004326312.1 involved in capsule formation, putative YP_004326341.1 glycosyl hydrolase family 70 glycosyltransferase,COG5263 glucan-binding domain (YG repeat) YP_004326342.1 N-terminal HTH domain predicted, rgg is involved in the H2O2 resistance phenotype in S. pyogenes YP_004326365.1 programmed frameshift YP_004326366.1 programmed frameshift YP_004326369.1 membrane protein, 11 TM helices predicted YP_004326389.1 3 TM helices predicted YP_004326400.1 membrane protein, 4 TM helices predicted YP_004326435.1 GTP-sensing transcriptional pleiotropic repressor YP_004326436.1 Superfamily II DNA and RNA helicases YP_004326448.1 PhnA; Uncharacterized Zn-ribbon-containing protein involved in phosphonate metabolism YP_004326469.1 Zinc-dependent metalloprotease; MMP_like subfamily. This group contains matrix metalloproteinases (MMPs),serralysins, and the astacin_like family of proteases YP_004326473.1 membrane protein, 2 TM helices predicted YP_004326485.1 membrane protein, 7 TM helices predicted YP_004326539.1 metal dependent phosphohydrolases with conserved HD-motif YP_004326569.1 accessory secretory protein Asp3, putative YP_004326575.1 LPXTG motif YP_004326587.1 bacteriocin/pheromone-type, double glycine-cleavage motif YP_004326598.1 phosphopantetheine attachment site YP_004326609.1 membrane protein, 4 TM helices predicted YP_004326615.1 involved in posttranslational modification, protein turnover, chaperone function YP_004326624.1 choline-binding protein, COG5263, Glucan-binding domain (YG repeat) YP_004326634.1 LPXTG motif, YSIRK type signal peptide; V8-like Glu-specific endopeptidase, serine protease domain YP_004326635.1 truncation, putative YP_004326636.1 truncation, gene fragment YP_004326643.1 gene fragment; putative truncation YP_004326659.1 LPXTG motif YP_004326691.1 similar to orf203 of S. thermophilus bacteriophage Sfi21, immunity region YP_004326695.1 putative stress-responsive transcriptional regulator YP_004326698.1 putative membrane protein, 1 TM helix predicted YP_004326700.1 uncharacterised P-loop hydrolase; ATPase or kinase YP_004326711.1 membrane protein, 1 TM helix predicted YP_004326713.1 HAD superfamily, subfamily IIIB (Acid phosphatase) YP_004326737.1 ACT domain protein YP_004326774.1 induced during competence in Streptococcus pneumoniae YP_004326783.1 folC family protein YP_004326787.1 membrane bound lipoprotein YP_004326793.1 membrane protein, 4 TM helices predicted YP_004326796.1 integral membrane protein, 3 TM helices predicted YP_004326798.1 holiday junction resolvasome, DNA-binding subunit YP_004326800.1 Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators YP_004326810.1 proteins involved in ribonucleotide reduction YP_004326815.1 truncation, putative YP_004326818.1 acetylornithine deacetylase/succinyl-diaminopimelate desuccinylase /and related deacylases; peptidase family M20. This family includes a range of zinc metallopeptidases belonging to several families in the peptidase classification. Family M20 are glutamate carboxypeptidases YP_004326821.1 AzlD superfamily YP_004326825.1 putative truncation YP_004326840.1 membrane protein, 7 TM helices predicted YP_004326841.1 Bacteriocin (Lactococcin_972 family) These sequences represent bacteriocins related to lactococcin. Members tend to be found in association with a seven transmembrane putative immunity protein YP_004326842.1 Helix-turn-helix motif, XRE-family like proteins YP_004326843.1 Lysin (LysM) domain, found in a variety of enzymes involved in bacterial cell wall degradation. This domain may have a general peptidoglycan binding function YP_004326848.1 required for the biosynthesis of pneumococcal type 1 capsular polysaccharide YP_004326854.1 truncation, authentic frameshift YP_004326855.1 truncation, authentic frameshift YP_004326860.1 VirB4, Type IV secretory pathway YP_004326865.1 C-terminal fragment; truncation YP_004326870.1 N-terminal fragment; truncation YP_004326883.1 bacteriocin production and immunity YP_004326905.1 HTH domain YP_004326908.1 authentic stop codon YP_004326909.1 authentic stop codon YP_004326918.1 truncated gene, authentic frameshift in the N-terminal NMAT-domain YP_004326919.1 truncated gene, authentic frameshift in the N-terminal NMAT-domain YP_004326922.1 LPXTG-motif YP_004326928.1 LPXTG-motif YP_004326929.1 choline-binding protein, glucan-binding domain (YG repeat); CHAP domain. This domain corresponds to an amidase function YP_004326933.1 DHH family: It is predicted that this family of proteins all perform a phosphoesterase function. It included the single stranded DNA exonuclease RecJ YP_004326943.1 related to IS630-Spn1 transposase YP_004326944.1 truncation YP_004326945.1 truncated YP_004326946.1 frameshift, truncated YP_004326947.1 frameshift, truncated YP_004326948.1 frameshift, truncated YP_004326949.1 choline-binding protein, glucan-binding domain (YG repeat); CHAP domain. This domain corresponds to an amidase function YP_004326951.1 CHAP domain. This domain corresponds to an amidase function YP_004326963.1 IMP dehydrogenase / GMP reductase domain YP_004326972.1 truncated gene fragment