-- dump date   	20140620_083752
-- class       	Genbank::misc_feature
-- table       	misc_feature_note
-- id	note
936154000001	chromosomal replication initiation protein; Reviewed; Region: dnaA; PRK00149
936154000002	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
936154000003	Walker A motif; other site
936154000004	ATP binding site [chemical binding]; other site
936154000005	Walker B motif; other site
936154000006	arginine finger; other site
936154000007	C-terminal domain of bacterial DnaA proteins. The DNA-binding C-terminal domain of DnaA contains a helix-turn-helix motif that specifically interacts with the DnaA box, a 9-mer motif that occurs repetitively in the replication origin oriC. Multiple...; Region: Bac_DnaA_C; cd06571
936154000008	DnaA box-binding interface [nucleotide binding]; other site
936154000009	DNA polymerase III subunit beta; Validated; Region: PRK05643
936154000010	Beta clamp domain.  The beta subunit (processivity factor) of DNA polymerase III holoenzyme, refered to as the beta clamp, forms a ring shaped dimer that encircles dsDNA (sliding clamp) in bacteria.  The beta-clamp is structurally similar to the trimeric...; Region: beta_clamp; cd00140
936154000011	putative DNA binding surface [nucleotide binding]; other site
936154000012	dimer interface [polypeptide binding]; other site
936154000013	beta-clamp/clamp loader binding surface; other site
936154000014	beta-clamp/translesion DNA polymerase binding surface; other site
936154000015	Bacterial protein of unknown function (DUF951); Region: DUF951; pfam06107
936154000016	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
936154000017	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
936154000018	non-specific DNA binding site [nucleotide binding]; other site
936154000019	salt bridge; other site
936154000020	sequence-specific DNA binding site [nucleotide binding]; other site
936154000021	GTP-binding protein YchF; Reviewed; Region: PRK09601
936154000022	YchF GTPase; Region: YchF; cd01900
936154000023	G1 box; other site
936154000024	GTP/Mg2+ binding site [chemical binding]; other site
936154000025	Switch I region; other site
936154000026	G2 box; other site
936154000027	Switch II region; other site
936154000028	G3 box; other site
936154000029	G4 box; other site
936154000030	G5 box; other site
936154000031	TGS_YchF_C: This subfamily represents TGS domain-containing YchF GTP-binding protein, a universally conserved GTPase whose function is unknown. The N-terminal domain of the YchF protein belongs to the Obg-like family of GTPases, and some members of the...; Region: TGS_YchF_C; cd04867
936154000032	Peptidyl-tRNA hydrolase (PTH) is a monomeric protein that cleaves the ester bond linking the nascent peptide and tRNA when peptidyl-tRNA is released prematurely from the ribosome. This ensures the recycling of peptidyl-tRNAs into tRNAs produced through...; Region: PTH; cd00462
936154000033	putative active site [active]
936154000034	catalytic residue [active]
936154000035	potential frameshift: common BLAST hit: gi|251781475|ref|YP_002995776.1|  transcription-repair coupling factor
936154000036	Transcription-repair coupling factor (superfamily II helicase) [DNA replication, recombination, and repair / Transcription]; Region: Mfd; COG1197
936154000037	CarD-like/TRCF domain; Region: CarD_TRCF; smart01058
936154000038	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
936154000039	ATP binding site [chemical binding]; other site
936154000040	putative Mg++ binding site [ion binding]; other site
936154000041	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
936154000042	nucleotide binding region [chemical binding]; other site
936154000043	ATP-binding site [chemical binding]; other site
936154000044	This domain is found in proteins necessary for strand-specific repair in DNA such as TRCF in Escherichia coli; Region: TRCF; smart00982
936154000045	Multidrug and toxic compound extrusion family and similar proteins; Region: MATE_like; cl09326
936154000046	Membrane protein involved in the export of O-antigen and teichoic acid [General function prediction only]; Region: RfbX; COG2244
936154000047	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
936154000048	RNA binding surface [nucleotide binding]; other site
936154000049	Septum formation initiator [Cell division and chromosome partitioning]; Region: COG2919
936154000050	Septum formation initiator; Region: DivIC; pfam04977
936154000051	Beta-lactamase class A [Defense mechanisms]; Region: PenP; COG2367
936154000052	Beta-lactamase enzyme family; Region: Beta-lactamase2; pfam13354
936154000053	N-terminal domain of predicted ATPase of the PP-loop faimly implicated in cell cycle control [Cell division and chromosome partitioning]. This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases...; Region: PP-ATPase; cd01992
936154000054	tRNA(Ile)-lysidine synthase MesJ [Cell cycle control, cell division, chromosome partitioning]; Region: MesJ; COG0037
936154000055	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
936154000056	active site
936154000057	ATP-dependent Zn proteases [Posttranslational modification, protein turnover, chaperones]; Region: HflB; COG0465
936154000058	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
936154000059	Walker A motif; other site
936154000060	ATP binding site [chemical binding]; other site
936154000061	Walker B motif; other site
936154000062	arginine finger; other site
936154000063	Peptidase family M41; Region: Peptidase_M41; pfam01434
936154000064	amino acid transporter; Region: 2A0306; TIGR00909
936154000065	C-terminus of AA_permease; Region: AA_permease_C; pfam13906
936154000066	rod shape-determining protein MreC; Provisional; Region: PRK13922
936154000067	rod shape-determining protein MreC; Region: MreC; pfam04085
936154000068	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3883
936154000069	CHAP domain; Region: CHAP; pfam05257
936154000070	Surface antigen [General function prediction only]; Region: COG3942
936154000071	ribose-phosphate pyrophosphokinase; Provisional; Region: PRK02269
936154000072	N-terminal domain of ribose phosphate pyrophosphokinase; Region: Pribosyltran_N; pfam13793
936154000073	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
936154000074	active site
936154000075	aromatic amino acid aminotransferase; Validated; Region: PRK07309
936154000076	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
936154000077	pyridoxal 5'-phosphate binding site [chemical binding]; other site
936154000078	homodimer interface [polypeptide binding]; other site
936154000079	catalytic residue [active]
936154000080	Recombination protein O C terminal; Region: RecO_C; pfam02565
936154000081	putative phosphate acyltransferase; Provisional; Region: PRK05331
936154000082	Phosphopantetheine attachment site; Region: PP-binding; cl09936
936154000083	phosphoribosylaminoimidazole-succinocarboxamide synthase; Reviewed; Region: PRK09362
936154000084	bacterial and archaeal 5-aminoimidazole-4-(N-succinylcarboxamide) ribonucleotide (SAICAR) synthase; Region: SAICAR_synt_PurC; cd01415
936154000085	ATP binding site [chemical binding]; other site
936154000086	active site
936154000087	substrate binding site [chemical binding]; other site
936154000088	phosphoribosylformylglycinamidine synthase, clade II; Region: FGAM-synthase; TIGR01857
936154000089	AIR (aminoimidazole ribonucleotide) synthase related protein. This family includes Hydrogen expression/formation protein HypE, AIR synthases, FGAM (formylglycinamidine ribonucleotide) synthase and Selenophosphate synthetase (SelD). The N-terminal domain...; Region: PurM-like; cl10019
936154000090	PurL subunit of the formylglycinamide ribonucleotide amidotransferase (FGAR-AT), first repeat. FGAR-AT catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to formylglycinamidine ribonucleotide (FGAM), ADP; Region: PurL_repeat1; cd02203
936154000091	dimerization interface [polypeptide binding]; other site
936154000092	ATP binding site [chemical binding]; other site
936154000093	PurL subunit of the formylglycinamide ribonucleotide amidotransferase (FGAR-AT), second repeat. FGAR-AT catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to formylglycinamidine ribonucleotide (FGAM), ADP; Region: PurL_repeat2; cd02204
936154000094	dimerization interface [polypeptide binding]; other site
936154000095	ATP binding site [chemical binding]; other site
936154000096	Type 1 glutamine amidotransferase (GATase1)-like domain found in Formylglycinamide ribonucleotide amidotransferase; Region: GATase1_FGAR_AT; cd01740
936154000097	putative active site [active]
936154000098	catalytic triad [active]
936154000099	amidophosphoribosyltransferase; Provisional; Region: PRK07272
936154000100	Glutamine amidotransferases class-II (GN-AT)_GPAT- type. This domain is found at the N-terminus of  glutamine phosphoribosylpyrophosphate (Prpp) amidotransferase (GPATase) . The glutaminase domain catalyzes amide nitrogen transfer from glutamine to the...; Region: GPATase_N; cd00715
936154000101	active site
936154000102	tetramer interface [polypeptide binding]; other site
936154000103	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
936154000104	active site
936154000105	phosphoribosylaminoimidazole synthetase; Provisional; Region: PRK05385
936154000106	PurM (Aminoimidazole Ribonucleotide [AIR] synthetase), one of eleven enzymes required for purine biosynthesis, catalyzes the conversion of formylglycinamide ribonucleotide (FGAM) and ATP to AIR, ADP, and Pi, the fifth step in de novo purine biosynthesis; Region: PurM; cd02196
936154000107	dimerization interface [polypeptide binding]; other site
936154000108	putative ATP binding site [chemical binding]; other site
936154000109	phosphoribosylglycinamide formyltransferase; Reviewed; Region: purN; PRK05647
936154000110	Phosphoribosylglycinamide formyltransferase (GAR transformylase, GART); Region: FMT_core_GART; cd08645
936154000111	active site
936154000112	substrate binding site [chemical binding]; other site
936154000113	cosubstrate binding site; other site
936154000114	catalytic site [active]
936154000115	bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; Provisional; Region: purH; PRK00881
936154000116	Inosine monophosphate cyclohydrolase domain. This is the N-terminal domain in the purine biosynthesis pathway protein ATIC (purH). The bifunctional ATIC protein contains a C-terminal  ATIC formylase domain that formylates...; Region: IMPCH; cd01421
936154000117	purine monophosphate binding site [chemical binding]; other site
936154000118	dimer interface [polypeptide binding]; other site
936154000119	putative catalytic residues [active]
936154000120	AICARFT/IMPCHase bienzyme; Region: AICARFT_IMPCHas; smart00798
936154000121	AICARFT/IMPCHase bienzyme; Region: AICARFT_IMPCHas; cl03362
936154000122	Surface antigen [General function prediction only]; Region: COG3942
936154000123	CHAP domain; Region: CHAP; pfam05257
936154000124	Bacterial SH3 domain; Region: SH3_5; pfam08460
936154000125	phosphoribosylamine--glycine ligase; Provisional; Region: PRK00885
936154000126	Phosphoribosylglycinamide synthetase, N domain; Region: GARS_N; pfam02844
936154000127	Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Region: GARS_A; pfam01071
936154000128	Phosphoribosylglycinamide synthetase, C domain; Region: GARS_C; pfam02843
936154000129	Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase [Nucleotide transport and metabolism]; Region: PurE; COG0041
936154000130	phosphoribosylaminoimidazole carboxylase ATPase subunit; Reviewed; Region: PRK06019
936154000131	ATP-grasp domain; Region: ATP-grasp_4; cl17255
936154000132	adenylosuccinate lyase; Provisional; Region: PRK07492
936154000133	Adenylsuccinate lyase (ASL)_subgroup 1; Region: Adenylsuccinate_lyase_1; cd01360
936154000134	tetramer interface [polypeptide binding]; other site
936154000135	active site
936154000136	Adenylosuccinate lyase C-terminus; Region: ADSL_C; smart00998
936154000137	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
936154000138	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
936154000139	non-specific DNA binding site [nucleotide binding]; other site
936154000140	salt bridge; other site
936154000141	sequence-specific DNA binding site [nucleotide binding]; other site
936154000142	Holliday junction DNA helicase RuvB; Reviewed; Region: ruvB; PRK00080
936154000143	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
936154000144	Walker A motif; other site
936154000145	ATP binding site [chemical binding]; other site
936154000146	Walker B motif; other site
936154000147	arginine finger; other site
936154000148	Holliday junction DNA helicase ruvB C-terminus; Region: RuvB_C; pfam05491
936154000149	Low molecular weight phosphatase family; Region: LMWPc; cl00105
936154000150	active site
936154000151	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4642
936154000152	Predicted acyltransferases [Lipid metabolism]; Region: COG1835
936154000153	yrhL-like subfamily of SGNH-hydrolases, a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely...; Region: SGNH_hydrolase_yrhL_like; cd01840
936154000154	catalytic triad [active]
936154000155	catalytic triad [active]
936154000156	oxyanion hole [active]
936154000157	NAD(P)+-dependent aldehyde dehydrogenase superfamily; Region: ALDH-SF; cl11961
936154000158	NAD(P) binding site [chemical binding]; other site
936154000159	catalytic residues [active]
936154000160	NAD(P)+-dependent aldehyde dehydrogenase superfamily; Region: ALDH-SF; cl11961
936154000161	Dehydroquinate synthase-like (DHQ-like) and iron-containing alcohol dehydrogenases (Fe-ADH); Region: DHQ_Fe-ADH; cl02872
936154000162	Dehydroquinate synthase-like (DHQ-like) and iron-containing alcohol dehydrogenases (Fe-ADH); Region: DHQ_Fe-ADH; cl02872
936154000163	metal binding site [ion binding]; metal-binding site
936154000164	Threonine synthase catalyzes the final step of threonine biosynthesis. The conversion of O-phosphohomoserine into threonine and inorganic phosphate is pyridoxal 5'-phosphate dependent. The Thr-synth_1 CD includes members from higher plants; Region: Thr-synth_2; cd01560
936154000165	Threonine synthase [Amino acid transport and metabolism]; Region: ThrC; COG0498
936154000166	pyridoxal 5'-phosphate binding site [chemical binding]; other site
936154000167	catalytic residue [active]
936154000168	Na+-driven multidrug efflux pump [Defense mechanisms]; Region: NorM; COG0534
936154000169	Multidrug and toxic compound extrusion family and similar proteins; Region: MATE_like; cl09326
936154000170	Multidrug and toxic compound extrusion family and similar proteins; Region: MATE_like; cl09326
936154000171	Na+-driven multidrug efflux pump [Defense mechanisms]; Region: NorM; COG0534
936154000172	30S ribosomal protein S10; Reviewed; Region: rpsJ; PRK00596
936154000173	50S ribosomal protein L3; Validated; Region: rplC; PRK00001
936154000174	50S ribosomal protein L4; Provisional; Region: rplD; PRK05319
936154000175	50S ribosomal protein L23; Reviewed; Region: rplW; PRK05738
936154000176	50S ribosomal protein L2; Validated; Region: rplB; PRK09374
936154000177	Ribosomal Proteins L2, RNA binding domain; Region: Ribosomal_L2; pfam00181
936154000178	Ribosomal Proteins L2, C-terminal domain; Region: Ribosomal_L2_C; pfam03947
936154000179	30S ribosomal protein S19; Reviewed; Region: rpsS; PRK00357
936154000180	Ribosomal protein L22/L17e.  L22 (L17 in eukaryotes) is a core protein of the large ribosomal subunit.  It is the only ribosomal protein that interacts with all six domains of 23S rRNA, and is one of the proteins important for directing the proper...; Region: Ribosomal_L22; cd00336
936154000181	putative translocon binding site; other site
936154000182	protein-rRNA interface [nucleotide binding]; other site
936154000183	30S ribosomal protein S3; Reviewed; Region: rpsC; PRK00310
936154000184	K homology RNA-binding (KH) domain of the prokaryotic 30S small ribosomal subunit protein S3. S3  is part of the head region of the 30S ribosomal subunit and is believed to interact with mRNA as it threads its way from the latch into the channel.  The KH...; Region: 30S_S3_KH; cd02412
936154000185	G-X-X-G motif; other site
936154000186	Ribosomal protein S3, C-terminal domain; Region: Ribosomal_S3_C; pfam00189
936154000187	Ribosomal_L16_L10e: L16 is an essential protein in the large ribosomal subunit of bacteria, mitochondria, and chloroplasts. Large subunits that lack L16 are defective in peptidyl transferase activity, peptidyl-tRNA hydrolysis activity, association with...; Region: Ribosomal_L16_L10e; cd01433
936154000188	23S rRNA interface [nucleotide binding]; other site
936154000189	5S rRNA interface [nucleotide binding]; other site
936154000190	putative antibiotic binding site [chemical binding]; other site
936154000191	L25 interface [polypeptide binding]; other site
936154000192	L27 interface [polypeptide binding]; other site
936154000193	Ribosomal L29 protein/HIP.  L29 is a protein of the large ribosomal Subunit. A homolog, called heparin/heparan sulfate interacting protein (HIP), has also been identified in mammals.  L29 is located on the surface of the large ribosomal subunit, where it...; Region: Ribosomal_L29_HIP; cd00427
936154000194	23S rRNA interface [nucleotide binding]; other site
936154000195	putative translocon interaction site; other site
936154000196	signal recognition particle (SRP54) interaction site; other site
936154000197	L23 interface [polypeptide binding]; other site
936154000198	trigger factor interaction site; other site
936154000199	30S ribosomal protein S17; Reviewed; Region: rpsQ; PRK05610
936154000200	50S ribosomal protein L14; Validated; Region: rplN; PRK05483
936154000201	50S ribosomal protein L24; Reviewed; Region: rplX; PRK00004
936154000202	KOW motif of Ribosomal Protein L26; Region: KOW_RPL26; cd06089
936154000203	RNA binding site [nucleotide binding]; other site
936154000204	50S ribosomal protein L5; Validated; Region: rplE; PRK00010
936154000205	Ribosomal protein L5; Region: Ribosomal_L5; pfam00281
936154000206	ribosomal L5P family C-terminus; Region: Ribosomal_L5_C; pfam00673
936154000207	30S ribosomal protein S14; Reviewed; Region: rpsN; PRK08061
936154000208	30S ribosomal protein S8; Validated; Region: rpsH; PRK00136
936154000209	50S ribosomal protein L6; Validated; Region: rplF; PRK05498
936154000210	Ribosomal protein L6; Region: Ribosomal_L6; pfam00347
936154000211	Ribosomal protein L6; Region: Ribosomal_L6; pfam00347
936154000212	Ribosomal L18/L5e:  L18 (L5e) is a ribosomal protein found in the central protuberance (CP) of the large subunit. L18 binds 5S rRNA and induces a conformational change that stimulates the binding of L5 to 5S rRNA. Association of 5S rRNA with 23S rRNA...; Region: Ribosomal_L18_L5e; cd00432
936154000213	5S rRNA interface [nucleotide binding]; other site
936154000214	L27 interface [polypeptide binding]; other site
936154000215	23S rRNA interface [nucleotide binding]; other site
936154000216	L5 interface [polypeptide binding]; other site
936154000217	30S ribosomal protein S5; Validated; Region: rpsE; PRK00550
936154000218	Ribosomal protein S5, N-terminal domain; Region: Ribosomal_S5; pfam00333
936154000219	Ribosomal protein S5, C-terminal domain; Region: Ribosomal_S5_C; pfam03719
936154000220	Ribosomal protein L30, which is found in eukaryotes and prokaryotes but not in archaea, is one of the smallest ribosomal proteins with a molecular mass of about 7kDa. L30 binds the 23SrRNA as well as the 5S rRNA and is one of five ribosomal proteins that...; Region: Ribosomal_L30; cd01658
936154000221	23S rRNA binding site [nucleotide binding]; other site
936154000222	50S ribosomal protein L15; Reviewed; Region: rplO; PRK05592
936154000223	preprotein translocase subunit SecY; Reviewed; Region: secY; PRK09204
936154000224	SecY translocase; Region: SecY; pfam00344
936154000225	adenylate kinase; Reviewed; Region: adk; PRK00279
936154000226	Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine triphosphates (ATP) to adenosine monophosphates (AMP) and to yield adenosine diphosphates (ADP). This enzyme is required for the biosynthesis of ADP and is essential for...; Region: ADK; cd01428
936154000227	AMP-binding site [chemical binding]; other site
936154000228	ATP-AMP (Ap5A)-binding site [chemical binding]; other site
936154000229	S1_IF1: Translation Initiation Factor IF1, S1-like RNA-binding domain. IF1 contains an S1-like RNA-binding domain, which is found in a wide variety of RNA-associated proteins. Translation initiation includes a number of interrelated steps preceding the...; Region: S1_IF1; cd04451
936154000230	rRNA binding site [nucleotide binding]; other site
936154000231	predicted 30S ribosome binding site; other site
936154000232	Ribosomal protein L36; Region: Ribosomal_L36; pfam00444
936154000233	30S ribosomal protein S13; Validated; Region: rpsM; PRK05179
936154000234	30S ribosomal protein S13; Region: bact_S13; TIGR03631
936154000235	30S ribosomal protein S11; Validated; Region: PRK05309
936154000236	DNA-directed RNA polymerase subunit alpha; Provisional; Region: PRK05182
936154000237	N-terminal domain of the Alpha subunit of Bacterial RNA polymerase; Region: RNAP_alpha_NTD; cd06928
936154000238	alphaNTD homodimer interface [polypeptide binding]; other site
936154000239	alphaNTD - beta interaction site [polypeptide binding]; other site
936154000240	alphaNTD - beta' interaction site [polypeptide binding]; other site
936154000241	Bacterial RNA polymerase, alpha chain C terminal domain; Region: RNA_pol_A_CTD; pfam03118
936154000242	50S ribosomal protein L17; Validated; Region: rplQ; PRK05591
936154000243	tyrosine recombinase XerC; Region: recomb_XerC; TIGR02224
936154000244	phiLC3 phage and phage-related integrases, site-specific recombinases, DNA breaking-rejoining enzymes, C-terminal catalytic domain. This CD includes various bacterial (mainly gram positive) and phage integrases, including those similar to Lactococcus...; Region: INT_phiLC3_C; cd01189
936154000245	Int/Topo IB signature motif; other site
936154000246	Domain of unknown function (DUF3173); Region: DUF3173; pfam11372
936154000247	Plasmid replication protein; Region: Rep_2; pfam01719
936154000248	RNA helicase; Region: RNA_helicase; pfam00910
936154000249	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
936154000250	non-specific DNA binding site [nucleotide binding]; other site
936154000251	salt bridge; other site
936154000252	sequence-specific DNA binding site [nucleotide binding]; other site
936154000253	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) MazG-like domain found in integron-associated MazG (iMazG) proteins; Region: NTP-PPase_iMazG; cd11536
936154000254	homodimer interface [polypeptide binding]; other site
936154000255	putative chemical substrate binding site [chemical binding]; other site
936154000256	oligomer interface [polypeptide binding]; other site
936154000257	metal binding site [ion binding]; metal-binding site
936154000258	hypothetical protein; Provisional; Region: PRK09273
936154000259	Ribose 5-phosphate isomerase RpiB [Carbohydrate transport and metabolism]; Region: RpiB; COG0698
936154000260	DNA-binding transcriptional regulator SoxS; Provisional; Region: PRK10219
936154000261	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3708
936154000262	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
936154000263	S-adenosylmethionine binding site [chemical binding]; other site
936154000264	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
936154000265	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
936154000266	non-specific DNA binding site [nucleotide binding]; other site
936154000267	salt bridge; other site
936154000268	sequence-specific DNA binding site [nucleotide binding]; other site
936154000269	acetoin reductase; Validated; Region: PRK08643
936154000270	meso-2,3-butanediol dehydrogenase-like, classical (c) SDRs; Region: meso-BDH-like_SDR_c; cd05366
936154000271	NAD binding site [chemical binding]; other site
936154000272	homotetramer interface [polypeptide binding]; other site
936154000273	homodimer interface [polypeptide binding]; other site
936154000274	active site
936154000275	substrate binding site [chemical binding]; other site
936154000276	Transcriptional regulators [Transcription]; Region: PurR; COG1609
936154000277	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
936154000278	DNA binding site [nucleotide binding]
936154000279	domain linker motif; other site
936154000280	Type 1 periplasmic binding fold superfamily; Region: Periplasmic_Binding_Protein_Type_1; cl10011
936154000281	5-keto-4-deoxyuronate isomerase; Provisional; Region: PRK00924
936154000282	2-keto-3-deoxygluconate permease; Provisional; Region: PRK05274
936154000283	gluconate 5-dehydrogenase; Provisional; Region: PRK07097
936154000284	gluconate 5-dehydrogenase (Ga5DH)-like, classical (c) SDRs; Region: Ga5DH-like_SDR_c; cd05347
936154000285	NADP binding site [chemical binding]; other site
936154000286	homodimer interface [polypeptide binding]; other site
936154000287	active site
936154000288	Sugar phosphate isomerases/epimerases [Carbohydrate transport and metabolism]; Region: IolE; COG1082
936154000289	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
936154000290	2-keto-3-deoxygluconate kinase (KdgK) phosphorylates 2-keto-3-deoxygluconate (KDG) to form 2-keto-3-deoxy-6-phosphogluconate (KDGP). KDG is the common intermediate product, that allows organisms to channel D-glucuronate and/or D-galacturinate into the...; Region: KdgK; cd01166
936154000291	substrate binding site [chemical binding]; other site
936154000292	ATP binding site [chemical binding]; other site
936154000293	2-keto-3-deoxy-6-phosphogluconate aldolase [Carbohydrate transport and metabolism]; Region: Eda; COG0800
936154000294	KDPG and KHG aldolase; Region: KDPG_aldolase; cd00452
936154000295	active site
936154000296	intersubunit interface [polypeptide binding]; other site
936154000297	catalytic residue [active]
936154000298	FemAB family; Region: FemAB; pfam02388
936154000299	Acetyltransferase (GNAT) domain; Region: Acetyltransf_6; pfam13480
936154000300	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
936154000301	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
936154000302	Transcriptional regulators [Transcription]; Region: RpiR; COG1737
936154000303	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
936154000304	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
936154000305	putative active site [active]
936154000306	phenyl proprionate permease family protein; Region: 2A0127; TIGR00902
936154000307	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
936154000308	putative substrate translocation pore; other site
936154000309	Glycosyl hydrolase family 1; Region: Glyco_hydro_1; cl01046
936154000310	beta-galactosidase; Region: BGL; TIGR03356
936154000311	Domain of unknown function (DUF4352); Region: DUF4352; pfam11611
936154000312	Uncharacterized protein involved in propionate catabolism [General function prediction only]; Region: PrpD; COG2079
936154000313	H+/citrate symporter [Energy production and conversion]; Region: CitM; COG2851
936154000314	Citrate transporter; Region: CitMHS; pfam03600
936154000315	Transcriptional regulator [Transcription]; Region: LysR; COG0583
936154000316	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
936154000317	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
936154000318	dimerization interface [polypeptide binding]; other site
936154000319	Citrate lyase synthetase [Energy production and conversion]; Region: CitC; COG3053
936154000320	Citrate lyase ligase; Region: Citrate_lyase_ligase; cd02169
936154000321	putative active site [active]
936154000322	(T/H)XGH motif; other site
936154000323	Putative ammonia monooxygenase [General function prediction only]; Region: AbrB; COG3180
936154000324	membrane protein AbrB duplication; Region: Gneg_AbrB_dup; TIGR03082
936154000325	membrane protein AbrB duplication; Region: Gneg_AbrB_dup; TIGR03082
936154000326	ATP:dephospho-CoA triphosphoribosyl transferase; Region: CitG; cl00768
936154000327	Transcriptional regulators [Transcription]; Region: GntR; COG1802
936154000328	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
936154000329	DNA-binding site [nucleotide binding]; DNA binding site
936154000330	FCD domain; Region: FCD; pfam07729
936154000331	H+/citrate symporter [Energy production and conversion]; Region: CitM; COG2851
936154000332	Citrate transporter; Region: CitMHS; pfam03600
936154000333	acetyl-CoA carboxylase biotin carboxyl carrier protein subunit; Validated; Region: PRK06549
936154000334	The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850
936154000335	carboxyltransferase (CT) interaction site; other site
936154000336	biotinylation site [posttranslational modification]; other site
936154000337	Na+-transporting oxaloacetate decarboxylase beta subunit; Region: OAD_beta; pfam03977
936154000338	Oxaloacetate decarboxylase, gamma chain; Region: OAD_gamma; cl01458
936154000339	citrate lyase subunit gamma; Provisional; Region: PRK13253
936154000340	HpcH/HpaI aldolase/citrate lyase family; Region: HpcH_HpaI; cl17231
936154000341	Citrate lyase, alpha subunit [Energy production and conversion]; Region: CitF; COG3051
936154000342	2'-(5''-triphosphoribosyl)-3'- dephospho-CoA:apo-citrate lyase; Reviewed; Region: citX; PRK01392
936154000343	oxaloacetate decarboxylase; Provisional; Region: PRK12331
936154000344	Pyruvate carboxylase and Transcarboxylase 5S, carboxyltransferase domain; Region: DRE_TIM_PC_TC_5S; cd07937
936154000345	active site
936154000346	catalytic residues [active]
936154000347	metal binding site [ion binding]; metal-binding site
936154000348	homodimer binding site [polypeptide binding]; other site
936154000349	Phosphoenolpyruvate carboxykinase (PEPCK), a critical gluconeogenic enzyme, catalyzes the first committed step in the diversion of tricarboxylic acid cycle intermediates toward gluconeogenesis. It catalyzes the reversible decarboxylation and...; Region: PEPCK_HprK; cl00270
936154000350	active site
936154000351	nucleotide-binding site [chemical binding]; other site
936154000352	Glycerate kinase family; Region: Gly_kinase; cl00841
936154000353	Transcriptional regulators [Transcription]; Region: PurR; COG1609
936154000354	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
936154000355	DNA binding site [nucleotide binding]
936154000356	domain linker motif; other site
936154000357	Ligand binding domain of the lacI-like transcription regulator from a novel metal-reducing bacterium Alkaliphilus Metalliredigens (strain Qymf) and its close homologs; Region: PBP1_Qymf_like; cd06291
936154000358	dimerization interface [polypeptide binding]; other site
936154000359	ligand binding site [chemical binding]; other site
936154000360	sodium binding site [ion binding]; other site
936154000361	ABC-type polysaccharide transport system, permease component [Carbohydrate transport and metabolism]; Region: LplB; COG4209
936154000362	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
936154000363	dimer interface [polypeptide binding]; other site
936154000364	conserved gate region; other site
936154000365	putative PBP binding loops; other site
936154000366	ABC-ATPase subunit interface; other site
936154000367	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
936154000368	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
936154000369	dimer interface [polypeptide binding]; other site
936154000370	ABC-ATPase subunit interface; other site
936154000371	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
936154000372	Southampton virus-type processing peptidase; Region: Peptidase_C37; pfam05416
936154000373	Beta-fructosidases (levanase/invertase) [Carbohydrate transport and metabolism]; Region: SacC; COG1621
936154000374	Glycosyl hydrolase family 32, beta-fructosidases; Region: GH32_B_Fructosidase; cd08996
936154000375	substrate binding [chemical binding]; other site
936154000376	active site
936154000377	Glycosyl hydrolases family 32 C terminal; Region: Glyco_hydro_32C; pfam08244
936154000378	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
936154000379	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
936154000380	nucleotide binding site [chemical binding]; other site
936154000381	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
936154000382	sequence-specific DNA binding site [nucleotide binding]; other site
936154000383	salt bridge; other site
936154000384	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
936154000385	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
936154000386	non-specific DNA binding site [nucleotide binding]; other site
936154000387	salt bridge; other site
936154000388	sequence-specific DNA binding site [nucleotide binding]; other site
936154000389	x-prolyl-dipeptidyl aminopeptidase; Provisional; Region: PRK05371
936154000390	X-Prolyl dipeptidyl aminopeptidase PepX, N-terminal; Region: PepX_N; cl07696
936154000391	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
936154000392	X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain; Region: PepX_C; pfam08530
936154000393	Major intrinsic protein (MIP) superfamily. Members of the MIP superfamily function as membrane channels that selectively transport water, small neutral molecules, and ions out of and between cells. The channel proteins share a common fold: the N-terminal...; Region: MIP; cd00333
936154000394	amphipathic channel; other site
936154000395	Asn-Pro-Ala signature motifs; other site
936154000396	Sulfite exporter TauE/SafE; Region: TauE; pfam01925
936154000397	This domain superfamily is found in a variety of structurally related metalloproteins, including the type I extradiol dioxygenases, glyoxalase I and a group of antibiotic resistance proteins; Region: Glo_EDI_BRP_like; cd06587
936154000398	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
936154000399	Beta-lactamase; Region: Beta-lactamase; pfam00144
936154000400	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
936154000401	Coenzyme A binding pocket [chemical binding]; other site
936154000402	Ribonucleotide reductase and Pyruvate formate lyase; Region: RNR_PFL; cl09939
936154000403	DNA Polymerase IV/Kappa; Region: PolY_Pol_IV_kappa; cd03586
936154000404	active site
936154000405	DNA polymerase IV; Validated; Region: PRK02406
936154000406	DNA binding site [nucleotide binding]
936154000407	helicase, putative, RecD/TraA family; Region: recD_rel; TIGR01448
936154000408	AAA domain; Region: AAA_30; pfam13604
936154000409	Family description; Region: UvrD_C_2; pfam13538
936154000410	signal peptidase I, bacterial type; Region: sigpep_I_bact; TIGR02227
936154000411	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
936154000412	Catalytic site [active]
936154000413	The S24, S26 LexA/signal peptidase superfamily contains LexA-related and type I signal peptidase families. The S24 LexA protein domains include: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC 3.4.21.88), the...; Region: Peptidase_S24_S26; cl10465
936154000414	ribonuclease HIII; Provisional; Region: PRK00996
936154000415	Domain of unknown function (DUF3378); Region: DUF3378; pfam11858
936154000416	bacterial Ribonuclease HIII-like; Region: RNase_HII_bacteria_HIII_like; cd06590
936154000417	RNA/DNA hybrid binding site [nucleotide binding]; other site
936154000418	active site
936154000419	Uncharacterized membrane protein, required for colicin V production [General function prediction only]; Region: CvpA; COG1286
936154000420	Colicin V production protein; Region: Colicin_V; pfam02674
936154000421	recombination and DNA strand exchange inhibitor protein; Reviewed; Region: PRK00409
936154000422	MutS domain III; Region: MutS_III; pfam05192
936154000423	ATP-binding cassette domain of MutS2; Region: ABC_MutS2; cd03280
936154000424	Walker A/P-loop; other site
936154000425	ATP binding site [chemical binding]; other site
936154000426	Q-loop/lid; other site
936154000427	ABC transporter signature motif; other site
936154000428	Walker B; other site
936154000429	D-loop; other site
936154000430	H-loop/switch region; other site
936154000431	Smr domain; Region: Smr; pfam01713
936154000432	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
936154000433	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
936154000434	catalytic residues [active]
936154000435	30S ribosomal protein S6; Reviewed; Region: rpsF; PRK00453
936154000436	Single-stranded DNA-binding protein [DNA replication, recombination, and repair]; Region: Ssb; COG0629
936154000437	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
936154000438	dimer interface [polypeptide binding]; other site
936154000439	ssDNA binding site [nucleotide binding]; other site
936154000440	tetramer (dimer of dimers) interface [polypeptide binding]; other site
936154000441	30S ribosomal protein S18; Reviewed; Region: rpsR; PRK00391
936154000442	Protein of unknown function (DUF1129); Region: DUF1129; cl11555
936154000443	Mg2+ and Co2+ transporters [Inorganic ion transport and metabolism]; Region: CorA; COG0598
936154000444	uncharacterized bacterial subfamily of the Escherichia coli CorA-Salmonella typhimurium ZntB family; Region: EcCorA_ZntB-like_u2; cd12827
936154000445	Cl binding site [ion binding]; other site
936154000446	oligomer interface [polypeptide binding]; other site
936154000447	excinuclease ABC subunit A; Reviewed; Region: uvrA; PRK00349
936154000448	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
936154000449	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
936154000450	ATP-binding cassette domain II of the excision repair protein UvrA; Region: ABC_UvrA_II; cd03271
936154000451	Creatinase/Prolidase N-terminal domain; Region: Creatinase_N; pfam01321
936154000452	Xaa-Pro aminopeptidase [Amino acid transport and metabolism]; Region: PepP; COG0006
936154000453	Similar to Prolidase and Aminopeptidase P. The members of this subfamily presumably catalyse hydrolysis of Xaa-Pro dipeptides and/or release of any N-terminal amino acid, including proline, that is linked with proline; Region: APP-like; cd01092
936154000454	active site
936154000455	Deoxycytidylate deaminase domain. Deoxycytidylate deaminase catalyzes the deamination of dCMP to dUMP, providing the nucleotide substrate for thymidylate synthase. The enzyme binds Zn++, which is required for catalytic activity. The activity of the...; Region: deoxycytidylate_deaminase; cd01286
936154000456	catalytic motif [active]
936154000457	Zn binding site [ion binding]; other site
936154000458	elongation factor P; Validated; Region: PRK00529
936154000459	Elongation factor P (EF-P) KOW-like domain; Region: EFP_N; pfam08207
936154000460	S1_EF-P_repeat_1: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_1; cd04470
936154000461	RNA binding site [nucleotide binding]; other site
936154000462	S1_EF-P_repeat_2: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_2; cd05794
936154000463	RNA binding site [nucleotide binding]; other site
936154000464	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1302
936154000465	transcription antitermination protein NusB; Reviewed; Region: nusB; PRK00202
936154000466	putative RNA binding site [nucleotide binding]; other site
936154000467	Transcriptional regulators [Transcription]; Region: PurR; COG1609
936154000468	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
936154000469	DNA binding site [nucleotide binding]
936154000470	domain linker motif; other site
936154000471	Ligand binding domain of the lacI-like transcription regulator from a novel metal-reducing bacterium Alkaliphilus Metalliredigens (strain Qymf) and its close homologs; Region: PBP1_Qymf_like; cd06291
936154000472	dimerization interface [polypeptide binding]; other site
936154000473	ligand binding site [chemical binding]; other site
936154000474	sodium binding site [ion binding]; other site
936154000475	sucrose-6-phosphate hydrolase; Region: scrB_fam; TIGR01322
936154000476	Glycosyl hydrolase family 32, beta-fructosidases; Region: GH32_B_Fructosidase; cd08996
936154000477	substrate binding [chemical binding]; other site
936154000478	active site
936154000479	Glycosyl hydrolases family 32 C terminal; Region: Glyco_hydro_32C; pfam08244
936154000480	PTS system, sucrose-specific IIBC component; Region: PTS-II-BC-sucr; TIGR01996
936154000481	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
936154000482	active site turn [active]
936154000483	phosphorylation site [posttranslational modification]
936154000484	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
936154000485	Phosphotransferase system IIA components [Carbohydrate transport and metabolism]; Region: NagE; COG2190
936154000486	HPr interaction site; other site
936154000487	glycerol kinase (GK) interaction site [polypeptide binding]; other site
936154000488	active site
936154000489	phosphorylation site [posttranslational modification]
936154000490	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
936154000491	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
936154000492	nucleotide binding site [chemical binding]; other site
936154000493	Transcriptional regulators [Transcription]; Region: RpiR; COG1737
936154000494	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
936154000495	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
936154000496	putative active site [active]
936154000497	Phosphotransferase system cellobiose-specific component IIC [Carbohydrate transport and metabolism]; Region: CelB; COG1455
936154000498	cellobiose phosphotransferase system IIC component; Reviewed; Region: celD; PRK09592
936154000499	Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase [Carbohydrate transport and metabolism]; Region: BglB; COG2723
936154000500	Phosphomannose isomerase [Carbohydrate transport and metabolism]; Region: ManA; COG1482
936154000501	mannose-6-phosphate isomerase, class I; Region: manA; TIGR00218
936154000502	preprotein translocase subunit SecA; Reviewed; Region: PRK12904
936154000503	SecA preprotein cross-linking domain; Region: SecA_PP_bind; smart00958
936154000504	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
936154000505	nucleotide binding region [chemical binding]; other site
936154000506	ATP-binding site [chemical binding]; other site
936154000507	SEC-C motif; Region: SEC-C; pfam02810
936154000508	4'-phosphopantetheinyl transferase; Provisional; Region: acpS; PRK00070
936154000509	alanine racemase; Reviewed; Region: alr; PRK00053
936154000510	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Alanine Racemase; Region: PLPDE_III_AR; cd00430
936154000511	active site
936154000512	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
936154000513	dimer interface [polypeptide binding]; other site
936154000514	substrate binding site [chemical binding]; other site
936154000515	catalytic residues [active]
936154000516	ATP-dependent DNA helicase RecG; Provisional; Region: PRK10917
936154000517	Y-family of DNA polymerases; Region: PolY; cl12025
936154000518	RecG_wedge_OBF: A subfamily of OB folds corresponding to the OB fold found in the N-terminal (wedge) domain of Escherichia coli RecG. RecG is a branched-DNA-specific helicase, which catalyzes the interconversion of a DNA replication fork to a...; Region: RecG_wedge_OBF; cd04488
936154000519	generic binding surface II; other site
936154000520	ssDNA binding site; other site
936154000521	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
936154000522	ATP binding site [chemical binding]; other site
936154000523	putative Mg++ binding site [ion binding]; other site
936154000524	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
936154000525	nucleotide binding region [chemical binding]; other site
936154000526	ATP-binding site [chemical binding]; other site
936154000527	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
936154000528	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
936154000529	active site
936154000530	catalytic tetrad [active]
936154000531	Type II (periplasmic) bacterial L-asparaginase; Region: L-asparaginase_II; cd08964
936154000532	active site
936154000533	homotetramer interface [polypeptide binding]; other site
936154000534	homodimer interface [polypeptide binding]; other site
936154000535	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
936154000536	haloacid dehalogenase-like hydrolase; Region: Hydrolase_3; pfam08282
936154000537	active site
936154000538	motif I; other site
936154000539	motif II; other site
936154000540	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cl17915
936154000541	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) MazG-like domain found in Exiguobacterium sibiricum YP_001813558.1 protein and its bacterial homologs; Region: NTP-PPase_YP_001813558; cd11545
936154000542	putative nucleotide binding site [chemical binding]; other site
936154000543	putative metal binding site [ion binding]; other site
936154000544	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
936154000545	Ligand Binding Site [chemical binding]; other site
936154000546	aminotransferase AlaT; Validated; Region: PRK09265
936154000547	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
936154000548	pyridoxal 5'-phosphate binding site [chemical binding]; other site
936154000549	homodimer interface [polypeptide binding]; other site
936154000550	catalytic residue [active]
936154000551	Pleiotropic transcriptional repressor [Transcription]; Region: CodY; COG4465
936154000552	CodY GAF-like domain; Region: CodY; pfam06018
936154000553	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
936154000554	dimerization interface [polypeptide binding]; other site
936154000555	putative Zn2+ binding site [ion binding]; other site
936154000556	putative DNA binding site [nucleotide binding]; other site
936154000557	Isochorismatase family; Region: Isochorismatase; pfam00857
936154000558	Cysteine hydrolases; This family contains amidohydrolases, like CSHase (N-carbamoylsarcosine amidohydrolase), involved in creatine metabolism and nicotinamidase, converting nicotinamide to nicotinic acid and ammonia in the pyridine nucleotide cycle. It...; Region: cysteine_hydrolases; cd00431
936154000559	catalytic triad [active]
936154000560	conserved cis-peptide bond; other site
936154000561	Uncharacterized protein YrkD from Bacillus subtilis and related domains; this domain superfamily was previously known as part of DUF156; Region: BsYrkD-like_DUF156; cd10155
936154000562	putative homodimer interface [polypeptide binding]; other site
936154000563	putative homotetramer interface [polypeptide binding]; other site
936154000564	putative metal binding site [ion binding]; other site
936154000565	putative homodimer-homodimer interface [polypeptide binding]; other site
936154000566	putative allosteric switch controlling residues; other site
936154000567	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
936154000568	active site residue [active]
936154000569	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
936154000570	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
936154000571	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
936154000572	active site residue [active]
936154000573	Integrase core domain; Region: rve_2; pfam13333
936154000574	HTH domain; Region: HTH_11; pfam08279
936154000575	FOG: CBS domain [General function prediction only]; Region: COG0517
936154000576	The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called...; Region: CBS_pair_4; cd04617
936154000577	PEP synthetase regulatory protein; Provisional; Region: PRK05339
936154000578	potential frameshift: common BLAST hit: gi|222153630|ref|YP_002562807.1| pyruvate phosphate dikinase
936154000579	pyruvate phosphate dikinase; Provisional; Region: PRK09279
936154000580	Pyruvate phosphate dikinase, PEP/pyruvate binding domain; Region: PPDK_N; pfam01326
936154000581	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
936154000582	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
936154000583	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
936154000584	aspartyl/glutamyl-tRNA amidotransferase subunit C; Reviewed; Region: gatC; PRK00034
936154000585	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases [Translation, ribosomal structure and biogenesis]; Region: GatA; COG0154
936154000586	aspartyl/glutamyl-tRNA amidotransferase subunit A; Reviewed; Region: gatA; PRK00012
936154000587	aspartyl/glutamyl-tRNA amidotransferase subunit B; Validated; Region: gatB; PRK05477
936154000588	GatB/GatE catalytic domain; Region: GatB_N; pfam02934
936154000589	GatB domain; Region: GatB_Yqey; pfam02637
936154000590	5-aminoimidazole-4-(N-succinylcarboxamide) ribonucleotide (SAICAR) synthase; Region: SAICAR_synt; cl00231
936154000591	ATP binding site [chemical binding]; other site
936154000592	active site
936154000593	substrate binding site [chemical binding]; other site
936154000594	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
936154000595	EamA-like transporter family; Region: EamA; pfam00892
936154000596	Predicted membrane protein [Function unknown]; Region: COG2261
936154000597	ACT domain proteins similar to the yet uncharacterized Streptococcus pneumoniae ACT domain protein; Region: ACT_1ZPV; cd04872
936154000598	Uncharacterized proteins with similarity to Ribonucleotide reductase and Pyruvate formate lyase; Region: RNR_PFL_like_DUF711; cd08025
936154000599	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
936154000600	catalytic core [active]
936154000601	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
936154000602	D-alanyl-D-alanine carboxypeptidase [Cell envelope biogenesis, outer membrane]; Region: VanY; COG1876
936154000603	D-alanyl-D-alanine carboxypeptidase; Region: VanY; pfam02557
936154000604	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase; Region: Glucosaminidase; cl17361
936154000605	heat-inducible transcription repressor; Provisional; Region: hrcA; PRK00082
936154000606	Winged helix-turn-helix transcription repressor, HrcA DNA-binding; Region: HrcA_DNA-bdg; pfam03444
936154000607	GrpE; Region: GrpE; pfam01025
936154000608	GrpE is the adenine nucleotide exchange factor of DnaK (Hsp70)-type ATPases. The GrpE dimer binds to the ATPase domain of Hsp70 catalyzing the dissociation of ADP, which enables rebinding of ATP, one step in the Hsp70 reaction cycle in protein folding; Region: GrpE; cd00446
936154000609	dimer interface [polypeptide binding]; other site
936154000610	hsp70 (ATPase domain) interactions [polypeptide binding]; other site
936154000611	chaperone protein DnaK; Region: prok_dnaK; TIGR02350
936154000612	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
936154000613	nucleotide binding site [chemical binding]; other site
936154000614	chaperone protein DnaJ; Provisional; Region: PRK14276
936154000615	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
936154000616	HSP70 interaction site [polypeptide binding]; other site
936154000617	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cl03262
936154000618	substrate binding site [polypeptide binding]; other site
936154000619	Zinc finger domain of DnaJ and HSP40; Region: DnaJ_zf; cd10719
936154000620	Zn binding sites [ion binding]; other site
936154000621	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cd10747
936154000622	substrate binding site [polypeptide binding]; other site
936154000623	dimer interface [polypeptide binding]; other site
936154000624	enoyl-CoA hydratase; Region: PLN02600
936154000625	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
936154000626	substrate binding site [chemical binding]; other site
936154000627	oxyanion hole (OAH) forming residues; other site
936154000628	trimer interface [polypeptide binding]; other site
936154000629	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
936154000630	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
936154000631	putative Zn2+ binding site [ion binding]; other site
936154000632	putative DNA binding site [nucleotide binding]; other site
936154000633	3-oxoacyl-(acyl carrier protein) synthase III; Reviewed; Region: PRK09352
936154000634	Ketoacyl-acyl carrier protein synthase III (KASIII) initiates the elongation in type II fatty acid synthase systems. It is found in bacteria and plants. Elongation of fatty acids in the type II systems occurs by Claisen condensation of malonyl-acyl...; Region: KAS_III; cd00830
936154000635	dimer interface [polypeptide binding]; other site
936154000636	active site
936154000637	CoA binding pocket [chemical binding]; other site
936154000638	acyl carrier protein; Provisional; Region: acpP; PRK00982
936154000639	putative enoyl-[acyl-carrier-protein] reductase II; Region: enACPred_II; TIGR03151
936154000640	2-Nitropropane dioxygenase (NPD), one of the nitroalkane oxidizing enzyme families, catalyzes oxidative denitrification of nitroalkanes to their corresponding carbonyl compounds and nitrites. NDP is a member of the NAD(P)H-dependent flavin oxidoreductase...; Region: NPD_like; cd04730
936154000641	FMN binding site [chemical binding]; other site
936154000642	substrate binding site [chemical binding]; other site
936154000643	putative catalytic residue [active]
936154000644	(acyl-carrier-protein) S-malonyltransferase [Lipid metabolism]; Region: FabD; COG0331
936154000645	malonyl CoA-acyl carrier protein transacylase; Region: fabD; TIGR00128
936154000646	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05557
936154000647	beta-Keto acyl carrier protein reductase (BKR), involved in Type II FAS, classical (c) SDRs; Region: BKR_SDR_c; cd05333
936154000648	NAD(P) binding site [chemical binding]; other site
936154000649	homotetramer interface [polypeptide binding]; other site
936154000650	homodimer interface [polypeptide binding]; other site
936154000651	active site
936154000652	3-oxoacyl-(acyl carrier protein) synthase II; Reviewed; Region: PRK07314
936154000653	Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen...; Region: KAS_I_II; cd00834
936154000654	dimer interface [polypeptide binding]; other site
936154000655	active site
936154000656	acetyl-CoA carboxylase biotin carboxyl carrier protein subunit; Validated; Region: PRK06302
936154000657	The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850
936154000658	carboxyltransferase (CT) interaction site; other site
936154000659	biotinylation site [posttranslational modification]; other site
936154000660	FabZ is a 17kD beta-hydroxyacyl-acyl carrier protein (ACP) dehydratase that primarily catalyzes the dehydration of beta-hydroxyacyl-ACP to trans-2-acyl-ACP, the third step in the elongation phase of the bacterial/ plastid, type II, fatty-acid...; Region: FabZ; cd01288
936154000661	acetyl-CoA carboxylase biotin carboxylase subunit; Validated; Region: PRK08591
936154000662	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
936154000663	Carbamoyl-phosphate synthase L chain, ATP binding domain; Region: CPSase_L_D2; pfam02786
936154000664	Biotin carboxylase C-terminal domain; Region: Biotin_carb_C; smart00878
936154000665	malonate decarboxylase subunit beta; Reviewed; Region: PRK07189; cl17682
936154000666	Acetyl-CoA carboxylase alpha subunit [Lipid metabolism]; Region: AccA; cl17345
936154000667	D-alanyl-D-alanine carboxypeptidase; Region: VanY; pfam02557
936154000668	seryl-tRNA synthetase; Provisional; Region: PRK05431
936154000669	Seryl-tRNA synthetase N-terminal domain; Region: Seryl_tRNA_N; pfam02403
936154000670	Seryl-tRNA synthetase (SerRS) class II core catalytic domain. SerRS is responsible for the attachment of serine to the 3' OH group of ribose of the appropriate tRNA. This domain It is primarily responsible for ATP-dependent formation of the enzyme...; Region: SerRS_core; cd00770
936154000671	dimer interface [polypeptide binding]; other site
936154000672	active site
936154000673	motif 1; other site
936154000674	motif 2; other site
936154000675	motif 3; other site
936154000676	Acyltransferase family; Region: Acyl_transf_3; pfam01757
936154000677	Predicted O-acyltransferase [General function prediction only]; Region: COG3274
936154000678	Domain of unknown function (DUF956); Region: DUF956; pfam06115
936154000679	Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IID [Carbohydrate transport and metabolism]; Region: ManZ; COG3716
936154000680	PTS system mannose-specific transporter subunit IIC; Provisional; Region: PRK15065
936154000681	PTS system mannose-specific transporter subunits IIAB; Provisional; Region: PRK15088
936154000682	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cd00006
936154000683	active pocket/dimerization site; other site
936154000684	active site
936154000685	phosphorylation site [posttranslational modification]
936154000686	PTS_IIB, PTS system, Mannose/sorbose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_man; cd00001
936154000687	active site
936154000688	phosphorylation site [posttranslational modification]
936154000689	Xanthine/uracil/vitamin C permease [Nucleotide transport and    metabolism]; Region: COG2252
936154000690	Predicted ATPase or kinase [General function prediction only]; Region: COG0802
936154000691	putative acetyltransferase YhhY; Provisional; Region: PRK10140
936154000692	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
936154000693	Coenzyme A binding pocket [chemical binding]; other site
936154000694	Transcriptional regulator [Transcription]; Region: LytR; COG1316
936154000695	HINT (histidine triad nucleotide-binding protein) subgroup: Members of this CD belong to the superfamily of histidine triad hydrolases that act on alpha-phosphate of ribonucleotides. This subgroup includes members from all three forms of cellular life; Region: HINT_subgroup; cd01277
936154000696	HIT family signature motif; other site
936154000697	catalytic residue [active]
936154000698	ABC-type Na+ transport system, ATPase component [Energy production and conversion / Inorganic ion transport and metabolism]; Region: NatA; COG4555
936154000699	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
936154000700	Walker A/P-loop; other site
936154000701	ATP binding site [chemical binding]; other site
936154000702	Q-loop/lid; other site
936154000703	ABC transporter signature motif; other site
936154000704	Walker B; other site
936154000705	D-loop; other site
936154000706	H-loop/switch region; other site
936154000707	Bacterial ABC transporter protein EcsB; Region: EcsB; cl11542
936154000708	Thiamine kinase and related kinases [Coenzyme transport and metabolism]; Region: ycfN; COG0510
936154000709	Phosphotransferase enzyme family; Region: APH; pfam01636
936154000710	substrate binding site [chemical binding]; other site
936154000711	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
936154000712	S-adenosylmethionine binding site [chemical binding]; other site
936154000713	ribosome maturation protein RimP; Reviewed; Region: PRK00092
936154000714	Bacillus subtilis YxlS-like, C-terminal domain; Region: YlxS_C; cd01734
936154000715	putative oligomer interface [polypeptide binding]; other site
936154000716	putative RNA binding site [nucleotide binding]; other site
936154000717	transcription elongation factor NusA; Provisional; Region: nusA; PRK12327
936154000718	NusA N-terminal domain; Region: NusA_N; pfam08529
936154000719	S1_NusA: N-utilizing substance A protein (NusA), S1-like RNA-binding domain. S1-like RNA-binding domains are found in a wide variety of RNA-associated proteins. NusA is a transcription elongation factor containing an N-terminal catalytic domain and three...; Region: S1_NusA; cd04455
936154000720	RNA binding site [nucleotide binding]; other site
936154000721	homodimer interface [polypeptide binding]; other site
936154000722	NusA-like KH domain; Region: KH_5; pfam13184
936154000723	NusA_K homology RNA-binding domain (KH). NusA is an essential multifunctional transcription elongation factor that is universally conserved among prokaryotes and archaea. NusA anti-termination function plays an important role in the expression of...; Region: NusA_KH; cd02134
936154000724	G-X-X-G motif; other site
936154000725	Protein of unknown function (DUF448); Region: DUF448; pfam04296
936154000726	putative RNA binding cleft [nucleotide binding]; other site
936154000727	hypothetical protein; Provisional; Region: PRK07283
936154000728	Translation initiation factor IF-2, N-terminal region; Region: IF2_N; pfam04760
936154000729	translation initiation factor IF-2; Validated; Region: infB; PRK05306
936154000730	Translation initiation factor IF-2, N-terminal region; Region: IF2_N; pfam04760
936154000731	Initiation Factor 2 (IF2)/ eukaryotic Initiation Factor 5B (eIF5B) family; Region: IF2_eIF5B; cd01887
936154000732	G1 box; other site
936154000733	putative GEF interaction site [polypeptide binding]; other site
936154000734	GTP/Mg2+ binding site [chemical binding]; other site
936154000735	Switch I region; other site
936154000736	G2 box; other site
936154000737	G3 box; other site
936154000738	Switch II region; other site
936154000739	G4 box; other site
936154000740	G5 box; other site
936154000741	This family represents the domain II of bacterial Initiation Factor 2 (IF2) and its eukaryotic mitochondrial homologue mtIF2. IF2, the largest initiation factor is an essential GTP binding protein. In E. coli three natural forms of IF2 exist in the cell; Region: IF2_mtIF2_II; cd03702
936154000742	Translation-initiation factor 2; Region: IF-2; pfam11987
936154000743	mtIF2_IVc: this family represents the C2 subdomain of domain IV of mitochondrial translation initiation factor 2 (mtIF2) which adopts a beta-barrel fold displaying a high degree of structural similarity with domain II of the translation elongation factor...; Region: mtIF2_IVc; cd03692
936154000744	ribosome-binding factor A; Validated; Region: rbfA; PRK00521
936154000745	Predicted transcriptional regulator [Transcription]; Region: COG3682
936154000746	copper transport repressor, CopY/TcrY family; Region: CopY_TcrY; TIGR02698
936154000747	Cation transport ATPase [Inorganic ion transport and metabolism]; Region: ZntA; COG2217
936154000748	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
936154000749	metal-binding site [ion binding]
936154000750	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
936154000751	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
936154000752	motif II; other site
936154000753	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
936154000754	metal-binding site [ion binding]
936154000755	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
936154000756	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
936154000757	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
936154000758	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
936154000759	active site
936154000760	phosphorylation site [posttranslational modification]
936154000761	Phosphotransferase system, galactitol-specific IIB component [Carbohydrate transport and metabolism]; Region: SgaB; COG3414
936154000762	active site
936154000763	P-loop; other site
936154000764	phosphorylation site [posttranslational modification]
936154000765	Phosphotransferase system, galactitol-specific IIC component [Carbohydrate transport and metabolism]; Region: GatC; COG3775
936154000766	PTS system sugar-specific permease component; Region: EIIC-GAT; pfam03611
936154000767	Ribose/Galactose Isomerase; Region: LacAB_rpiB; cl00485
936154000768	galactose-6-phosphate isomerase subunit LacB; Reviewed; Region: PRK08622
936154000769	1-phosphofructokinase (FruK), minor 6-phosphofructokinase (pfkB) and related sugar kinases. FruK plays an important role in the predominant pathway for fructose utilisation.This group also contains tagatose-6-phophate kinase, an enzyme of the tagatose...; Region: FruK_PfkB_like; cd01164
936154000770	tagatose-6-phosphate kinase; Region: lacC; TIGR01231
936154000771	putative substrate binding site [chemical binding]; other site
936154000772	putative ATP binding site [chemical binding]; other site
936154000773	tagatose 1,6-diphosphate aldolase; Reviewed; Region: PRK12399
936154000774	Aldose 1-epimerase, similar to Lactococcus lactis lacX; Region: Aldose_epim_lacX; cd09024
936154000775	active site
936154000776	catalytic residues [active]
936154000777	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
936154000778	haloacid dehalogenase-like hydrolase; Region: Hydrolase_3; pfam08282
936154000779	active site
936154000780	motif I; other site
936154000781	motif II; other site
936154000782	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
936154000783	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
936154000784	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
936154000785	Uncharacterized protein conserved in bacteria [Function unknown]; Region: DegV; COG1307
936154000786	Uncharacterized protein, DegV family COG1307; Region: DegV; pfam02645
936154000787	N-acetylglucosamine-6-phosphate deacetylase [Carbohydrate transport and metabolism]; Region: NagA; COG1820
936154000788	N-acetylglucosamine-6-phosphate deacetylase, NagA, catalyzes the hydrolysis of the N-acetyl group of N-acetyl-glucosamine-6-phosphate (GlcNAc-6-P) to glucosamine 6-phosphate and acetate. This is the first committed step in the biosynthetic pathway to...; Region: NagA; cd00854
936154000789	active site
936154000790	dimer interface [polypeptide binding]; other site
936154000791	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
936154000792	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
936154000793	active site
936154000794	catalytic tetrad [active]
936154000795	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1755
936154000796	Class II Glycyl-tRNA synthetase (GlyRS) alpha subunit core catalytic domain. GlyRS functions as a homodimer in eukaryotes, archaea and some bacteria and as a heterotetramer in the remainder of prokaryotes and in arabidopsis. It is responsible for the...; Region: GlyRS_alpha_core; cd00733
936154000797	dimer interface [polypeptide binding]; other site
936154000798	motif 1; other site
936154000799	active site
936154000800	motif 2; other site
936154000801	motif 3; other site
936154000802	glycyl-tRNA synthetase subunit beta; Validated; Region: glyS; PRK01233
936154000803	Anticodon-binding domain of class Ia aminoacyl tRNA synthetases and similar domains; Region: Anticodon_Ia_like; cl12020
936154000804	glycerol kinase; Provisional; Region: glpK; PRK00047
936154000805	Escherichia coli glycerol kinase-like proteins; belongs to the FGGY family of carbohydrate kinases; Region: FGGY_EcGK_like; cd07786
936154000806	N- and C-terminal domain interface [polypeptide binding]; other site
936154000807	active site
936154000808	MgATP binding site [chemical binding]; other site
936154000809	catalytic site [active]
936154000810	metal binding site [ion binding]; metal-binding site
936154000811	glycerol binding site [chemical binding]; other site
936154000812	homotetramer interface [polypeptide binding]; other site
936154000813	homodimer interface [polypeptide binding]; other site
936154000814	FBP binding site [chemical binding]; other site
936154000815	protein IIAGlc interface [polypeptide binding]; other site
936154000816	Glycerol-3-phosphate dehydrogenase [Energy production and conversion]; Region: GlpA; COG0578
936154000817	Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family) [Carbohydrate transport and metabolism]; Region: GlpF; COG0580
936154000818	amphipathic channel; other site
936154000819	Asn-Pro-Ala signature motifs; other site
936154000820	coenzyme A disulfide reductase; Reviewed; Region: PRK09564
936154000821	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
936154000822	Mga helix-turn-helix domain; Region: Mga; pfam05043
936154000823	Transaldolase-like fructose-6-phosphate aldolases (FSA) found in bacteria and archaea; Region: Transaldolase_FSA; cd00956
936154000824	active site
936154000825	intersubunit interactions; other site
936154000826	catalytic residue [active]
936154000827	Transketolase [Carbohydrate transport and metabolism]; Region: TktA; COG0021
936154000828	Thiamine pyrophosphate (TPP) family, Transketolase (TK) subfamily, TPP-binding module; TK catalyzes the transfer of a two-carbon unit from ketose phosphates to aldose phosphates. In heterotrophic organisms, TK provides a link between glycolysis and the...; Region: TPP_TK; cd02012
936154000829	TPP-binding site [chemical binding]; other site
936154000830	dimer interface [polypeptide binding]; other site
936154000831	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
936154000832	PYR/PP interface [polypeptide binding]; other site
936154000833	dimer interface [polypeptide binding]; other site
936154000834	TPP binding site [chemical binding]; other site
936154000835	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
936154000836	Enterocin A Immunity; Region: EntA_Immun; pfam08951
936154000837	ABC-type Na+ transport system, ATPase component [Energy production and conversion / Inorganic ion transport and metabolism]; Region: NatA; COG4555
936154000838	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
936154000839	Walker A/P-loop; other site
936154000840	ATP binding site [chemical binding]; other site
936154000841	Q-loop/lid; other site
936154000842	ABC transporter signature motif; other site
936154000843	Walker B; other site
936154000844	D-loop; other site
936154000845	H-loop/switch region; other site
936154000846	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
936154000847	Glutamate 5-kinase [Amino acid transport and metabolism]; Region: ProB; COG0263
936154000848	AAK_G5K_ProB: Glutamate-5-kinase (G5K) catalyzes glutamate-dependent ATP cleavage; G5K transfers the terminal phosphoryl group of ATP to the gamma-carboxyl group of glutamate, in the first and controlling step of proline (and, in mammals, ornithine)...; Region: AAK_G5K_ProB; cd04242
936154000849	nucleotide binding site [chemical binding]; other site
936154000850	homotetrameric interface [polypeptide binding]; other site
936154000851	putative phosphate binding site [ion binding]; other site
936154000852	putative allosteric binding site; other site
936154000853	Gamma-glutamyl phosphate reductase (GPR), aldehyde dehydrogenase families 18 and 19; Region: ALDH_F18-19_ProA-GPR; cd07079
936154000854	gamma-glutamyl phosphate reductase; Region: proA; TIGR00407
936154000855	putative catalytic cysteine [active]
936154000856	Predicted S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis [Cell envelope biogenesis, outer membrane]; Region: COG0275
936154000857	MraW methylase family; Region: Methyltransf_5; pfam01795
936154000858	Protein required for the initiation of cell division [Cell division and chromosome partitioning]; Region: FtsL; COG4839
936154000859	Cell division protein FtsI/penicillin-binding protein 2 [Cell envelope biogenesis, outer membrane]; Region: FtsI; COG0768
936154000860	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
936154000861	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
936154000862	PASTA domain. This domain is found at the C-termini of several Penicillin-binding proteins (PBPs) and bacterial serine/threonine kinases. It is a small globular fold consisting of 3 beta-sheets and an alpha-helix. The name PASTA is derived from PBP and...; Region: PASTA; cl02768
936154000863	PASTA domain of PBP2x-like proteins, second repeat. Penicillin-binding proteins (PBPs) are the major targets for beta-lactam antibiotics, like penicillins and cephalosporins. Beta-lactam antibiotics specifically inhibit transpeptidase activity by...; Region: PASTA_Pbp2x-like_2; cd06575
936154000864	phospho-N-acetylmuramoyl-pentapeptide-transferase; Provisional; Region: mraY; PRK00108
936154000865	Phospho-N-acetylmuramoyl-pentapeptide-transferase (mraY) is an enzyme responsible for the formation of the first lipid intermediate in the synthesis of bacterial cell wall peptidoglycan. It catalyzes the formation of...; Region: GT_MraY; cd06852
936154000866	Mg++ binding site [ion binding]; other site
936154000867	putative catalytic motif [active]
936154000868	putative substrate binding site [chemical binding]; other site
936154000869	ATP-dependent RNA helicase SrmB; Provisional; Region: PRK11192
936154000870	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
936154000871	ATP binding site [chemical binding]; other site
936154000872	Mg++ binding site [ion binding]; other site
936154000873	motif III; other site
936154000874	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
936154000875	nucleotide binding region [chemical binding]; other site
936154000876	ATP-binding site [chemical binding]; other site
936154000877	Bacterial periplasmic substrate-binding proteins; Region: PBPb; smart00062
936154000878	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
936154000879	substrate binding pocket [chemical binding]; other site
936154000880	membrane-bound complex binding site; other site
936154000881	hinge residues; other site
936154000882	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
936154000883	dimer interface [polypeptide binding]; other site
936154000884	conserved gate region; other site
936154000885	putative PBP binding loops; other site
936154000886	ABC-ATPase subunit interface; other site
936154000887	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
936154000888	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
936154000889	Walker A/P-loop; other site
936154000890	ATP binding site [chemical binding]; other site
936154000891	Q-loop/lid; other site
936154000892	ABC transporter signature motif; other site
936154000893	Walker B; other site
936154000894	D-loop; other site
936154000895	H-loop/switch region; other site
936154000896	thioredoxin-disulfide reductase; Region: TRX_reduct; TIGR01292
936154000897	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
936154000898	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
936154000899	Gamma-aminobutyrate permease and related permeases [Amino acid transport and metabolism]; Region: AnsP; COG1113
936154000900	Predicted membrane protein [Function unknown]; Region: COG3619
936154000901	methionyl-tRNA synthetase; Reviewed; Region: PRK12267
936154000902	catalytic core domain of methioninyl-tRNA synthetases; Region: MetRS_core; cd00814
936154000903	active site
936154000904	HIGH motif; other site
936154000905	KMSKS motif; other site
936154000906	Anticodon-binding domain of methionyl tRNA synthetases; Region: Anticodon_Ia_Met; cd07957
936154000907	tRNA binding surface [nucleotide binding]; other site
936154000908	anticodon binding site; other site
936154000909	tRNA-binding-domain-containing Escherichia coli methionyl-tRNA synthetase (EcMetRS)-like proteins.  This family includes EcMetRS and Aquifex aeolicus Trbp111 (AaTrbp111). This domain has general tRNA binding properties.  MetRS aminoacylates methionine...; Region: tRNA_bind_EcMetRS_like; cd02800
936154000910	putative tRNA-binding site [nucleotide binding]; other site
936154000911	dimer interface [polypeptide binding]; other site
936154000912	uncharacterized bacterial subfamily of the Escherichia coli CorA-Salmonella typhimurium ZntB family; Region: EcCorA_ZntB-like_u2; cd12827
936154000913	Cl binding site [ion binding]; other site
936154000914	CorA-like Mg2+ transporter protein; Region: CorA; pfam01544
936154000915	oligomer interface [polypeptide binding]; other site
936154000916	Protein of unknown function (DUF2829); Region: DUF2829; pfam11195
936154000917	3-ketoacyl-(acyl-carrier-protein) reductase; Provisional; Region: fabG; PRK06550
936154000918	classical (c) SDRs; Region: SDR_c; cd05233
936154000919	NAD(P) binding site [chemical binding]; other site
936154000920	active site
936154000921	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
936154000922	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
936154000923	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
936154000924	bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase; Provisional; Region: glmU; PRK14354
936154000925	N-terminal domain of bacterial GlmU; Region: GT2_GlmU_N_bac; cd02540
936154000926	Substrate binding site; other site
936154000927	Mg++ binding site; other site
936154000928	N-acetyl-glucosamine-1-phosphate uridyltransferase (GlmU), C-terminal left-handed beta-helix (LbH) acetyltransferase domain: GlmU is also known as UDP-N-acetylglucosamine pyrophosphorylase. It is a bifunctional bacterial enzyme that catalyzes two...; Region: LbH_GlmU_C; cd03353
936154000929	active site
936154000930	substrate binding site [chemical binding]; other site
936154000931	CoA binding site [chemical binding]; other site
936154000932	nudix-type nucleoside diphosphatase, YffH/AdpP family; Region: TIGR00052
936154000933	ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+; Region: ADPRase_NUDT5; cd03424
936154000934	dimer interface [polypeptide binding]; other site
936154000935	ADP-ribose binding site [chemical binding]; other site
936154000936	active site
936154000937	nudix motif; other site
936154000938	metal binding site [ion binding]; metal-binding site
936154000939	Phosphorylase superfamily; Region: PNP_UDP_1; cl00303
936154000940	Phosphorylase superfamily; Region: PNP_UDP_1; cl00303
936154000941	Mn-dependent transcriptional regulator [Transcription]; Region: TroR; COG1321
936154000942	Iron dependent repressor, N-terminal DNA binding domain; Region: Fe_dep_repress; pfam01325
936154000943	Iron dependent repressor, metal binding and dimerisation domain; Region: Fe_dep_repr_C; pfam02742
936154000944	FeoA domain; Region: FeoA; pfam04023
936154000945	ABC-type metal ion transport system, periplasmic component/surface adhesin [Inorganic ion transport and metabolism]; Region: LraI; COG0803
936154000946	Helical backbone metal receptor (TroA-like domain). These proteins have been shown to function in the ABC transport of ferric siderophores and metal ions such as Mn2+, Fe3+, Cu2+ and/or Zn2+.  Their ligand binding site is formed in the interface between...; Region: TroA-like; cl00262
936154000947	ABC-type metal ion transport system, periplasmic component/surface adhesin [Inorganic ion transport and metabolism]; Region: LraI; COG0803
936154000948	Helical backbone metal receptor (TroA-like domain). These proteins have been shown to function in the ABC transport of ferric siderophores and metal ions such as Mn2+, Fe3+, Cu2+ and/or Zn2+.  Their ligand binding site is formed in the interface between...; Region: TroA-like; cl00262
936154000949	potential frameshift: common BLAST hit: gi|251781903|ref|YP_002996205.1| manganese transport system ATP-binding protein
936154000950	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
936154000951	Walker A/P-loop; other site
936154000952	ATP binding site [chemical binding]; other site
936154000953	Q-loop/lid; other site
936154000954	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
936154000955	ABC transporter signature motif; other site
936154000956	Walker B; other site
936154000957	D-loop; other site
936154000958	H-loop/switch region; other site
936154000959	cyclophilin: cyclophilin-type peptidylprolyl cis- trans isomerases. This family contains eukaryotic, bacterial and archeal proteins which exhibit a peptidylprolyl cis- trans isomerases activity (PPIase, Rotamase) and in addition bind the...; Region: cyclophilin; cl00197
936154000960	active site
936154000961	DNA segregation ATPase FtsK/SpoIIIE and related proteins [Cell division and chromosome partitioning]; Region: FtsK; COG1674
936154000962	FtsK/SpoIIIE family; Region: FtsK_SpoIIIE; pfam01580
936154000963	Ftsk gamma domain; Region: Ftsk_gamma; pfam09397
936154000964	50S ribosomal protein L11; Validated; Region: rplK; PRK00140
936154000965	Ribosomal protein L11. Ribosomal protein L11, together with proteins L10 and L7/L12, and 23S rRNA, form the L7/L12 stalk on the surface of the large subunit of the ribosome. The homologous eukaryotic cytoplasmic protein is also called 60S ribosomal...; Region: Ribosomal_L11; cd00349
936154000966	23S rRNA interface [nucleotide binding]; other site
936154000967	L7/L12 interface [polypeptide binding]; other site
936154000968	putative thiostrepton binding site; other site
936154000969	L25 interface [polypeptide binding]; other site
936154000970	Ribosomal protein L1.  The L1 protein, located near the E-site of the ribosome, forms part of the L1 stalk along with 23S rRNA.  In bacteria and archaea, L1 functions both as a ribosomal protein that binds rRNA, and as a translation repressor that binds...; Region: Ribosomal_L1; cd00403
936154000971	mRNA/rRNA interface [nucleotide binding]; other site
936154000972	UMP kinase (UMPK)-Ec, the microbial/chloroplast uridine monophosphate kinase (uridylate kinase) enzyme that catalyzes UMP phosphorylation and plays a key role in pyrimidine nucleotide biosynthesis; regulation of this process is via feed-back control and...; Region: AAK_UMPK-PyrH-Ec; cd04254
936154000973	putative nucleotide binding site [chemical binding]; other site
936154000974	uridine monophosphate binding site [chemical binding]; other site
936154000975	homohexameric interface [polypeptide binding]; other site
936154000976	ribosome recycling factor; Reviewed; Region: frr; PRK00083
936154000977	Ribosome recycling factor (RRF). Ribosome recycling factor dissociates the posttermination complex, composed of the ribosome, deacylated tRNA, and mRNA, after termination of translation.  Thus ribosomes are "recycled" and ready for another...; Region: RRF; cd00520
936154000978	hinge region; other site
936154000979	Predicted RNA-bindining protein (contains S1 and HTH domains) [General function prediction only]; Region: COG2996
936154000980	S1 domain; Region: S1_2; pfam13509
936154000981	methionine sulfoxide reductase A; Provisional; Region: PRK14054
936154000982	hypothetical protein; Provisional; Region: PRK13672
936154000983	potential frameshift: common BLAST hit: gi|94991901|ref|YP_600000.1| Myosin-crossreactive antigen
936154000984	Streptococcal 67 kDa myosin-cross-reactive antigen like family; Region: Strep_67kDa_ant; cl17487
936154000985	Streptococcal 67 kDa myosin-cross-reactive antigen like family; Region: Strep_67kDa_ant; cl17487
936154000986	Phosphate starvation-inducible protein PhoH, predicted ATPase [Signal transduction mechanisms]; Region: PhoH; COG1702
936154000987	PhoH-like protein; Region: PhoH; pfam02562
936154000988	Uracil-DNA glycosylases (UDG) and related enzymes; Region: UDG_like; cl00483
936154000989	ligand binding site [chemical binding]; other site
936154000990	metal-binding heat shock protein; Provisional; Region: PRK00016
936154000991	Diacylglycerol kinase [Cell envelope biogenesis, outer membrane]; Region: DgkA; COG0818
936154000992	GTPase Era; Reviewed; Region: era; PRK00089
936154000993	E. coli Ras-like protein (Era) is a multifunctional GTPase; Region: Era; cd04163
936154000994	G1 box; other site
936154000995	GTP/Mg2+ binding site [chemical binding]; other site
936154000996	Switch I region; other site
936154000997	G2 box; other site
936154000998	Switch II region; other site
936154000999	G3 box; other site
936154001000	G4 box; other site
936154001001	G5 box; other site
936154001002	KH domain; Region: KH_2; pfam07650
936154001003	Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly...; Region: Nudix_Hydrolase_18; cd04677
936154001004	nudix motif; other site
936154001005	coenzyme A disulfide reductase; Reviewed; Region: PRK09564
936154001006	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
936154001007	Walker A/P-loop; other site
936154001008	ATP binding site [chemical binding]; other site
936154001009	Q-loop/lid; other site
936154001010	LytTr DNA-binding domain; Region: LytTR; pfam04397
936154001011	formamidopyrimidine/5-formyluracil/ 5-hydroxymethyluracil DNA glycosylase; Validated; Region: PRK01103
936154001012	N-terminal domain of Escherichia coli Fpg1/MutM and related bacterial DNA glycosylases; Region: EcFpg-like_N; cd08966
936154001013	DNA binding site [nucleotide binding]
936154001014	catalytic residue [active]
936154001015	H2TH interface [polypeptide binding]; other site
936154001016	putative catalytic residues [active]
936154001017	turnover-facilitating residue; other site
936154001018	intercalation triad [nucleotide binding]; other site
936154001019	8OG recognition residue [nucleotide binding]; other site
936154001020	putative reading head residues; other site
936154001021	Formamidopyrimidine-DNA glycosylase H2TH domain; Region: H2TH; pfam06831
936154001022	Zinc finger found in FPG and IleRS; Region: zf-FPG_IleRS; pfam06827
936154001023	Dephospho-CoA kinase [Coenzyme metabolism]; Region: CoaE; COG0237
936154001024	Dephospho-coenzyme A kinase (DPCK, EC 2.7.1.24) catalyzes the phosphorylation of dephosphocoenzyme A (dCoA) to yield CoA, which is the final step in CoA biosynthesis; Region: DPCK; cd02022
936154001025	CoA-binding site [chemical binding]; other site
936154001026	ATP-binding [chemical binding]; other site
936154001027	Predicted membrane protein [Function unknown]; Region: COG2364
936154001028	Uncharacterized BCR, YitT family COG1284; Region: DUF161; pfam02588
936154001029	Domain of unknown function DUF87; Region: DUF87; pfam01935
936154001030	Bacterial protein of unknown function (DUF853); Region: DUF853; pfam05872
936154001031	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
936154001032	putative substrate translocation pore; other site
936154001033	50S ribosomal protein L33; Validated; Region: rpmG; PRK00595
936154001034	preprotein translocase subunit SecG; Reviewed; Region: secG; PRK06870
936154001035	RNB domain; Region: RNB; pfam00773
936154001036	This domain is the catalytic domain of ribonuclease II; Region: RNB; smart00955
936154001037	S1_RNase_R: RNase R C-terminal S1 domain. RNase R is a processive 3' to 5' exoribonuclease, which is a homolog of RNase II. RNase R degrades RNA with secondary structure having a 3' overhang of at least 7 nucleotides. RNase R and PNPase...; Region: S1_RNase_R; cd04471
936154001038	RNA binding site [nucleotide binding]; other site
936154001039	Small protein B (SmpB) is a component of the trans-translation system in prokaryotes for releasing stalled ribosome from damaged messenger RNAs; Region: SmpB; cd09294
936154001040	SmpB-tmRNA interface; other site
936154001041	Glyoxalase I catalyzes the isomerization of the hemithioacetal, formed by a 2-oxoaldehyde and glutathione, to S-D-lactoylglutathione; Region: Glyoxalase_I; cd07233
936154001042	dimer interface [polypeptide binding]; other site
936154001043	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
936154001044	active site
936154001045	metal binding site [ion binding]; metal-binding site
936154001046	glutathione binding site [chemical binding]; other site
936154001047	NAD(P)H:FMN oxidoreductase family. This domain catalyzes the reduction of flavin, nitrocompound, quinones and azo compounds using NADH or NADPH as an electron donor. The enzyme is a homodimer, and each monomer binds a FMN as co-factor. This family...; Region: NfsB_like_nitroreductase; cd02149
936154001048	dimer interface [polypeptide binding]; other site
936154001049	FMN binding site [chemical binding]; other site
936154001050	6-phospho-beta-glucosidase; Reviewed; Region: celA; PRK09589
936154001051	beta-galactosidase; Region: BGL; TIGR03356
936154001052	cellobiose phosphotransferase system IIB component; Reviewed; Region: celB; PRK09590
936154001053	active site
936154001054	P-loop; other site
936154001055	phosphorylation site [posttranslational modification]
936154001056	Transcriptional antiterminator [Transcription]; Region: BglG; COG3711
936154001057	HTH domain; Region: HTH_11; pfam08279
936154001058	Mga helix-turn-helix domain; Region: Mga; pfam05043
936154001059	PRD domain; Region: PRD; pfam00874
936154001060	PRD domain; Region: PRD; pfam00874
936154001061	PTS_IIB_bgl_like: the PTS (phosphotransferase system) IIB domain of a family of sensory systems composed of a membrane-bound sugar-sensor (similar to BglF) and a transcription antiterminator (similar to BglG) which regulate expression of genes involved...; Region: PTS_IIB_bgl_like; cd05568
936154001062	active site
936154001063	P-loop; other site
936154001064	phosphorylation site [posttranslational modification]
936154001065	PTS_IIA, PTS system, lactose/cellobiose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_lac; cd00215
936154001066	methionine cluster; other site
936154001067	active site
936154001068	phosphorylation site [posttranslational modification]
936154001069	metal binding site [ion binding]; metal-binding site
936154001070	Phosphotransferase system cellobiose-specific component IIC [Carbohydrate transport and metabolism]; Region: CelB; COG1455
936154001071	cellobiose phosphotransferase system IIC component; Reviewed; Region: celD; PRK09592
936154001072	Uncharacterized conserved protein [Function unknown]; Region: COG3589
936154001073	Bacterial protein of unknown function (DUF871); Region: DUF871; pfam05913
936154001074	Xaa-Pro aminopeptidase [Amino acid transport and metabolism]; Region: PepP; COG0006
936154001075	Creatinase/Prolidase N-terminal domain; Region: Creatinase_N; pfam01321
936154001076	Similar to Prolidase and Aminopeptidase P. The members of this subfamily presumably catalyse hydrolysis of Xaa-Pro dipeptides and/or release of any N-terminal amino acid, including proline, that is linked with proline; Region: APP-like; cd01092
936154001077	active site
936154001078	Ligand-binding domain of the catabolite control protein A (CcpA), which functions as the major transcriptional regulator of carbon catabolite repression/regulation; Region: PBP1_CcpA_like; cd06298
936154001079	dimerization interface [polypeptide binding]; other site
936154001080	effector binding site; other site
936154001081	cytoplasmic alpha-amylase; Reviewed; Region: PRK09441
936154001082	Alpha amylase catalytic domain found in bacterial and fungal Alpha amylases (also called 1,4-alpha-D-glucan-4-glucanohydrolase); Region: AmyAc_bac_fung_AmyA; cd11318
936154001083	active site
936154001084	Na/Ca binding site [ion binding]; other site
936154001085	catalytic site [active]
936154001086	Domain of unknown function (DUF1939); Region: DUF1939; pfam09154
936154001087	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
936154001088	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
936154001089	This family is most closely related to the GT1 family of glycosyltransferases. UDP-glucose-diacylglycerol glucosyltransferase (UGDG; also known as 1,2-diacylglycerol 3-glucosyltransferase) catalyzes the transfer of glucose from UDP-glucose to 1; Region: GT1_UGDG_like; cd03817
936154001090	Glycosyltransferase Family 4; Region: Glyco_transf_4; pfam13439
936154001091	putative ADP-binding pocket [chemical binding]; other site
936154001092	DhaKLM operon coactivator DhaQ; Provisional; Region: PRK14483
936154001093	Dihydroxyacetone kinase [Carbohydrate transport and metabolism]; Region: DAK1; COG2376
936154001094	probable dihydroxyacetone kinase regulator; Region: DHAK_reg; TIGR02366
936154001095	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
936154001096	dihydroxyacetone kinase subunit DhaK; Provisional; Region: PRK14481; cl10557
936154001097	dihydroxyacetone kinase subunit DhaK; Provisional; Region: PRK14481; cl10557
936154001098	Dihydroxyacetone kinase [Carbohydrate transport and metabolism]; Region: DAK1; COG2376
936154001099	dihydroxyacetone kinase, phosphoprotein-dependent, L subunit; Region: dha_L_ycgS; TIGR02365
936154001100	phosphotransferase mannnose-specific family component IIA; Provisional; Region: PRK14484
936154001101	Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family) [Carbohydrate transport and metabolism]; Region: GlpF; COG0580
936154001102	amphipathic channel; other site
936154001103	Asn-Pro-Ala signature motifs; other site
936154001104	Protein of unknown function (DUF3114); Region: DUF3114; pfam11311
936154001105	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
936154001106	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
936154001107	dimer interface [polypeptide binding]; other site
936154001108	conserved gate region; other site
936154001109	putative PBP binding loops; other site
936154001110	ABC-ATPase subunit interface; other site
936154001111	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
936154001112	dimer interface [polypeptide binding]; other site
936154001113	conserved gate region; other site
936154001114	putative PBP binding loops; other site
936154001115	ABC-ATPase subunit interface; other site
936154001116	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
936154001117	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
936154001118	substrate binding pocket [chemical binding]; other site
936154001119	membrane-bound complex binding site; other site
936154001120	hinge residues; other site
936154001121	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
936154001122	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
936154001123	Walker A/P-loop; other site
936154001124	ATP binding site [chemical binding]; other site
936154001125	Q-loop/lid; other site
936154001126	ABC transporter signature motif; other site
936154001127	Walker B; other site
936154001128	D-loop; other site
936154001129	H-loop/switch region; other site
936154001130	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
936154001131	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
936154001132	active site
936154001133	phosphorylation site [posttranslational modification]
936154001134	intermolecular recognition site; other site
936154001135	dimerization interface [polypeptide binding]; other site
936154001136	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
936154001137	DNA binding site [nucleotide binding]
936154001138	potential frameshift: common BLAST hit: gi|222152721|ref|YP_002561898.1| sensor histidine kinase
936154001139	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: VicK; COG5002
936154001140	phosphate regulon sensor kinase PhoR; Region: phoR_proteo; TIGR02966
936154001141	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
936154001142	putative active site [active]
936154001143	heme pocket [chemical binding]; other site
936154001144	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
936154001145	dimer interface [polypeptide binding]; other site
936154001146	phosphorylation site [posttranslational modification]
936154001147	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
936154001148	ATP binding site [chemical binding]; other site
936154001149	Mg2+ binding site [ion binding]; other site
936154001150	G-X-G motif; other site
936154001151	Metal-dependent hydrolases of the beta-lactamase superfamily I [General function prediction only]; Region: PhnP; COG1235
936154001152	Predicted Zn-dependent hydrolases of the beta-lactamase fold [General function prediction only]; Region: COG2220
936154001153	ribonuclease III; Reviewed; Region: rnc; PRK00102
936154001154	RIBOc. Ribonuclease III C terminal domain. This group consists of eukaryotic, bacterial and archeal ribonuclease III (RNAse III) proteins. RNAse III is a double stranded RNA-specific endonuclease. Prokaryotic RNAse III is important in...; Region: RIBOc; cd00593
936154001155	dimerization interface [polypeptide binding]; other site
936154001156	active site
936154001157	metal binding site [ion binding]; metal-binding site
936154001158	Double-stranded RNA binding motif. Binding is not sequence specific but is highly specific for double stranded RNA. Found in a variety of proteins including dsRNA dependent protein kinase PKR, RNA helicases, Drosophila staufen protein, E. coli RNase III; Region: DSRM; cd00048
936154001159	dsRNA binding site [nucleotide binding]; other site
936154001160	ATP-binding cassette domain of barmotin, a member of the SMC protein family; Region: ABC_SMC_barmotin; cd03278
936154001161	AAA domain; Region: AAA_23; pfam13476
936154001162	Walker A/P-loop; other site
936154001163	ATP binding site [chemical binding]; other site
936154001164	Q-loop/lid; other site
936154001165	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
936154001166	haloacid dehalogenase-like hydrolase; Region: Hydrolase_3; pfam08282
936154001167	active site
936154001168	motif I; other site
936154001169	motif II; other site
936154001170	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
936154001171	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
936154001172	haloacid dehalogenase-like hydrolase; Region: Hydrolase_3; pfam08282
936154001173	active site
936154001174	motif I; other site
936154001175	motif II; other site
936154001176	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
936154001177	signal recognition particle-docking protein FtsY; Provisional; Region: PRK10416
936154001178	SRP54-type protein, helical bundle domain; Region: SRP54_N; pfam02881
936154001179	The signal recognition particle (SRP) mediates the transport to or across the plasma membrane in bacteria and the endoplasmic reticulum in eukaryotes. SRP recognizes N-terminal sighnal sequences of newly synthesized polypeptides at the ribosome. The...; Region: SRP; cd03115
936154001180	P loop; other site
936154001181	GTP binding site [chemical binding]; other site
936154001182	Flagellin N-methylase; Region: FliB; pfam03692
936154001183	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
936154001184	putative substrate translocation pore; other site
936154001185	Major Facilitator Superfamily; Region: MFS_1; pfam07690
936154001186	Predicted membrane protein [Function unknown]; Region: COG3689
936154001187	Predicted permeases [General function prediction only]; Region: COG0701
936154001188	This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_3; cd07241
936154001189	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
936154001190	putative metal binding site [ion binding]; other site
936154001191	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
936154001192	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
936154001193	active site
936154001194	phosphorylation site [posttranslational modification]
936154001195	intermolecular recognition site; other site
936154001196	dimerization interface [polypeptide binding]; other site
936154001197	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
936154001198	DNA binding site [nucleotide binding]
936154001199	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
936154001200	dimer interface [polypeptide binding]; other site
936154001201	phosphorylation site [posttranslational modification]
936154001202	ABC-type phosphate transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: PstS; COG0226
936154001203	PBP superfamily domain; Region: PBP_like_2; cl17296
936154001204	phosphate ABC transporter, permease protein PstA; Region: 3a0107s02c; TIGR00974
936154001205	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
936154001206	dimer interface [polypeptide binding]; other site
936154001207	conserved gate region; other site
936154001208	putative PBP binding loops; other site
936154001209	ABC-ATPase subunit interface; other site
936154001210	phosphate transporter ATP-binding protein; Provisional; Region: PRK14240
936154001211	ATP-binding cassette domain of the phosphate transport system; Region: ABC_PstB_phosphate_transporter; cd03260
936154001212	Walker A/P-loop; other site
936154001213	ATP binding site [chemical binding]; other site
936154001214	Q-loop/lid; other site
936154001215	ABC transporter signature motif; other site
936154001216	Walker B; other site
936154001217	D-loop; other site
936154001218	H-loop/switch region; other site
936154001219	PhoU domain; Region: PhoU; pfam01895
936154001220	Transcriptional accessory protein [Transcription]; Region: Tex; COG2183
936154001221	Tex-like protein N-terminal domain; Region: Tex_N; pfam09371
936154001222	Likely ribonuclease with RNase H fold; Region: YqgFc; smart00732
936154001223	S1_Tex: The C-terminal S1 domain of a transcription accessory factor called Tex, which has been characterized in Bordetella pertussis and Pseudomonas aeruginosa. The tex gene is essential in Bortella pertusis and is named for its role in toxin expression; Region: S1_Tex; cd05685
936154001224	RNA binding site [nucleotide binding]; other site
936154001225	hypothetical protein; Provisional; Region: PRK04351
936154001226	SprT homologues; Region: SprT; cl01182
936154001227	Putative stress-responsive transcriptional regulator [Transcription / Signal transduction mechanisms]; Region: PspC; COG1983
936154001228	HPr kinase/phosphorylase; Provisional; Region: PRK05428
936154001229	HPr Serine kinase N terminus; Region: Hpr_kinase_N; pfam02603
936154001230	HprK/P, the bifunctional histidine-containing protein kinase/phosphatase, controls the phosphorylation state of the phosphocarrier protein HPr and regulates the utilization of carbon sources by gram-positive bacteria. It catalyzes both the ATP-dependent...; Region: HprK_C; cd01918
936154001231	Hpr binding site; other site
936154001232	active site
936154001233	homohexamer subunit interaction site [polypeptide binding]; other site
936154001234	prolipoprotein diacylglyceryl transferase; Reviewed; Region: PRK12437
936154001235	Uncharacterized protein containing a divergent version of the methyl-accepting chemotaxis-like domain [General function prediction only]; Region: COG4768
936154001236	YtxH-like protein; Region: YtxH; pfam12732
936154001237	Protein of unknown function (DUF3270); Region: DUF3270; pfam11674
936154001238	Collagenase and related proteases [Posttranslational modification, protein turnover, chaperones]; Region: COG0826
936154001239	Peptidase family U32; Region: Peptidase_U32; pfam01136
936154001240	Collagenase and related proteases [Posttranslational modification, protein turnover, chaperones]; Region: COG0826
936154001241	Peptidase family U32; Region: Peptidase_U32; pfam01136
936154001242	Uncharacterized protein conserved in bacteria (DUF2128); Region: DUF2128; pfam09901
936154001243	ABC-type oligopeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: OppA; COG4166
936154001244	The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold; Region: PBP2_OppA; cd08504
936154001245	peptide binding site [polypeptide binding]; other site
936154001246	Protein of unknown function (DUF1006); Region: DUF1006; pfam06224
936154001247	imidazolonepropionase; Validated; Region: PRK09356
936154001248	Imidazolonepropionase/imidazolone-5-propionate hydrolase (Imidazolone-5PH) catalyzes the third step in the histidine degradation pathway, the hydrolysis of (S)-3-(5-oxo-4,5-dihydro-3H-imidazol-4-yl)propanoate to N-formimidoyl-L-glutamate. In bacteria; Region: Imidazolone-5PH; cd01296
936154001249	active site
936154001250	urocanate hydratase; Provisional; Region: PRK05414
936154001251	Glutamate formiminotransferase [Amino acid transport and metabolism]; Region: COG3643
936154001252	Formiminotransferase domain, N-terminal subdomain; Region: FTCD_N; pfam07837
936154001253	Formiminotransferase domain; Region: FTCD; pfam02971
936154001254	Methenyl tetrahydrofolate cyclohydrolase [Amino acid transport and metabolism]; Region: COG3404
936154001255	formate--tetrahydrofolate ligase; Provisional; Region: PRK13505
936154001256	Formyltetrahydrofolate synthetase (FTHFS) catalyzes the ATP-dependent activation of formate ion via its addition to the N10 position of tetrahydrofolate. FTHFS is a highly expressed key enzyme in both the Wood-Ljungdahl pathway of autotrophic CO2...; Region: FTHFS; cd00477
936154001257	Potassium binding sites [ion binding]; other site
936154001258	Cesium cation binding sites [ion binding]; other site
936154001259	HutD; Region: HutD; pfam05962
936154001260	amino acid transporter; Region: 2A0306; TIGR00909
936154001261	Phenylalanine ammonia-lyase (PAL) and histidine ammonia-lyase (HAL); Region: PAL-HAL; cd00332
936154001262	active sites [active]
936154001263	tetramer interface [polypeptide binding]; other site
936154001264	formimidoylglutamase; Provisional; Region: PRK13775
936154001265	Formimidoylglutamase or HutE; Region: Formimidoylglutamase; cd09988
936154001266	putative active site [active]
936154001267	putative metal binding site [ion binding]; other site
936154001268	DNA-binding transcriptional activator of the SARP family [Signal transduction mechanisms]; Region: DnrI; COG3629
936154001269	AAA ATPase domain; Region: AAA_16; pfam13191
936154001270	Predicted ATPase [General function prediction only]; Region: COG3899
936154001271	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429
936154001272	binding surface
936154001273	TPR motif; other site
936154001274	lysyl-tRNA synthetase; Reviewed; Region: lysS; PRK00484
936154001275	LysRS_N: N-terminal, anticodon recognition domain of lysyl-tRNA synthetases (LysRS). These enzymes are homodimeric class 2b aminoacyl-tRNA synthetases (aaRSs). This domain is a beta-barrel domain (OB fold) involved in binding the tRNA anticodon stem-loop; Region: LysRS_N; cd04322
936154001276	dimer interface [polypeptide binding]; other site
936154001277	putative anticodon binding site; other site
936154001278	Lys_tRNA synthetase (LysRS) class II core domain. Class II LysRS is a dimer which attaches a lysine to the 3' OH group of ribose of the appropriate tRNA. Its assignment to class II aaRS is based upon its structure and the presence of three...; Region: LysRS_core; cd00775
936154001279	motif 1; other site
936154001280	active site
936154001281	motif 2; other site
936154001282	motif 3; other site
936154001283	Predicted hydrolase (HAD superfamily) [General function prediction only]; Region: COG1011
936154001284	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
936154001285	motif II; other site
936154001286	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
936154001287	catalytic core [active]
936154001288	This CD includes cysteinyl-tRNA(Pro) deacylases from Haemophilus influenzae and Escherichia coli and other related bacterial proteins. These trans-acting, single-domain proteins are homologs of ProX and also the cis-acting prolyl-tRNA synthetase (ProRS)...; Region: YbaK_deacylase; cd00002
936154001289	putative deacylase active site [active]
936154001290	Thiamine transporter protein (Thia_YuaJ); Region: Thia_YuaJ; cl17491
936154001291	Lyzozyme M1 (1,4-beta-N-acetylmuramidase) [Cell envelope biogenesis, outer membrane]; Region: Acm; COG3757
936154001292	PlyB is a bacteriophage endolysin that displays potent lytic activity toward Bacillus anthracis.  PlyB has an N-terminal glycosyl hydrolase family 25 (GH25) catalytic domain and a C-terminal bacterial SH3-like domain, SH3b.  Both domains are required for...; Region: GH25_PlyB-like; cd06523
936154001293	active site
936154001294	Protein of unknown function (DUF3816); Region: DUF3816; pfam12822
936154001295	Peptidase Gluzincin family (thermolysin-like proteinases, TLPs) includes peptidases M1, M2, M3, M4, M13, M32 and M36 (fungalysins); Region: GluZincin; cl14813
936154001296	oligoendopeptidase F; Region: pepF; TIGR00181
936154001297	Zn binding site [ion binding]; other site
936154001298	Peptidase Gluzincin family (thermolysin-like proteinases, TLPs) includes peptidases M1, M2, M3, M4, M13, M32 and M36 (fungalysins); Region: GluZincin; cl14813
936154001299	phosphoenolpyruvate carboxylase; Reviewed; Region: PRK00009
936154001300	Bacterial cell division membrane protein [Cell division and chromosome partitioning]; Region: FtsW; COG0772
936154001301	elongation factor Tu; Reviewed; Region: PRK00049
936154001302	Elongation Factor Tu (EF-Tu) GTP-binding proteins; Region: EF_Tu; cd01884
936154001303	G1 box; other site
936154001304	GEF interaction site [polypeptide binding]; other site
936154001305	GTP/Mg2+ binding site [chemical binding]; other site
936154001306	Switch I region; other site
936154001307	G2 box; other site
936154001308	G3 box; other site
936154001309	Switch II region; other site
936154001310	G4 box; other site
936154001311	G5 box; other site
936154001312	EFTU_II: Elongation factor Tu domain II. Elongation factors Tu (EF-Tu) are three-domain GTPases with an essential function in the elongation phase of mRNA translation. The GTPase center of EF-Tu is in the N-terminal domain (domain I), also known as the...; Region: EFTU_II; cd03697
936154001313	Domain III of elongation factor (EF) Tu. Ef-Tu consists of three structural domains, designated I, II and III. Domain III adopts a beta barrel structure. Domain III is involved in binding to both charged tRNA and binding to elongation factor Ts (EF-Ts); Region: EFTU_III; cd03707
936154001314	Antibiotic Binding Site [chemical binding]; other site
936154001315	triosephosphate isomerase; Provisional; Region: PRK14567
936154001316	Triosephosphate isomerase (TIM) is a glycolytic enzyme that catalyzes the interconversion of dihydroxyacetone phosphate and D-glyceraldehyde-3-phosphate. The reaction is very efficient and requires neither cofactors nor metal ions. TIM, usually...; Region: TIM; cd00311
936154001317	substrate binding site [chemical binding]; other site
936154001318	dimer interface [polypeptide binding]; other site
936154001319	catalytic triad [active]
936154001320	FemAB family; Region: FemAB; pfam02388
936154001321	sugar phosphate phosphatase; Provisional; Region: PRK10513
936154001322	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
936154001323	active site
936154001324	motif I; other site
936154001325	motif II; other site
936154001326	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
936154001327	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
936154001328	HD superfamily phosphohydrolases [General function prediction only]; Region: COG1078
936154001329	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
936154001330	Zn2+ binding site [ion binding]; other site
936154001331	Mg2+ binding site [ion binding]; other site
936154001332	Domain of unknown function (DUF1934); Region: DUF1934; pfam09148
936154001333	Cation efflux family; Region: Cation_efflux; cl00316
936154001334	Cation transport ATPase [Inorganic ion transport and metabolism]; Region: MgtA; COG0474
936154001335	Cation transporter/ATPase, N-terminus; Region: Cation_ATPase_N; pfam00690
936154001336	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
936154001337	Putative hydrolase of sodium-potassium ATPase alpha subunit; Region: Hydrolase_like2; pfam13246
936154001338	haloacid dehalogenase-like hydrolase; Region: HAD; pfam12710
936154001339	Cation transporting ATPase, C-terminus; Region: Cation_ATPase_C; pfam00689
936154001340	Glycerophosphodiester phosphodiesterase domain of Thermoanaerobacter tengcongensis and similar proteins; Region: GDPD_TtGDE_like; cd08563
936154001341	Glycerophosphoryl diester phosphodiesterase family; Region: GDPD; pfam03009
936154001342	active site
936154001343	catalytic site [active]
936154001344	metal binding site [ion binding]; metal-binding site
936154001345	dimer interface [polypeptide binding]; other site
936154001346	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
936154001347	metallophosphatase superfamily, metallophosphatase domain; Region: MPP_superfamily; cd00838
936154001348	active site
936154001349	metal binding site [ion binding]; metal-binding site
936154001350	Predicted phosphatase/phosphohexomutase [General function prediction only]; Region: COG0637
936154001351	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
936154001352	motif II; other site
936154001353	Firmicute fructose-1,6-bisphosphatase; Region: FBPase_2; pfam06874
936154001354	ATP synthase (F/14-kDa) subunit; Region: ATP-synt_F; cl00632
936154001355	epoxyqueuosine reductase; Region: TIGR00276
936154001356	Domain of unknown function (DUF1730); Region: DUF1730; pfam08331
936154001357	This domain is found in peptide chain release factors; Region: PCRF; smart00937
936154001358	Protein chain release factor B [Translation, ribosomal structure and biogenesis]; Region: PrfB; COG1186
936154001359	RF-1 domain; Region: RF-1; pfam00472
936154001360	Predicted ATPase involved in cell division [Cell division and chromosome partitioning]; Region: FtsE; COG2884
936154001361	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
936154001362	Walker A/P-loop; other site
936154001363	ATP binding site [chemical binding]; other site
936154001364	Q-loop/lid; other site
936154001365	ABC transporter signature motif; other site
936154001366	Walker B; other site
936154001367	D-loop; other site
936154001368	H-loop/switch region; other site
936154001369	Cell division protein [Cell division and chromosome partitioning]; Region: FtsX; COG2177
936154001370	cell division ABC transporter subunit FtsX; Provisional; Region: ftsX; PRK11026
936154001371	Zn-dependent hydrolases, including glyoxylases [General function prediction only]; Region: GloB; COG0491
936154001372	bifunctional ATP-dependent DNA helicase/DNA polymerase III subunit epsilon; Validated; Region: PRK07246
936154001373	DEDDh 3'-5' exonuclease domain family; Region: DEDDh; cd06127
936154001374	active site
936154001375	catalytic site [active]
936154001376	substrate binding site [chemical binding]; other site
936154001377	DEAD/DEAH box helicase; Region: DEAD; pfam00270
936154001378	Helicase C-terminal domain; Region: Helicase_C_2; pfam13307
936154001379	aspartate aminotransferase; Provisional; Region: PRK05764
936154001380	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
936154001381	pyridoxal 5'-phosphate binding site [chemical binding]; other site
936154001382	homodimer interface [polypeptide binding]; other site
936154001383	catalytic residue [active]
936154001384	asparaginyl-tRNA synthetase; Validated; Region: asnC; PRK03932
936154001385	AsnRS_cyto_like_N: N-terminal, anticodon recognition domain of the type found in human and Saccharomyces cerevisiae cytoplasmic asparaginyl-tRNA synthetase (AsnRS), in Brugia malayai AsnRs and, in various putative bacterial AsnRSs.  This domain is a...; Region: AsnRS_cyto_like_N; cd04323
936154001386	putative dimer interface [polypeptide binding]; other site
936154001387	putative anticodon binding site; other site
936154001388	Asx tRNA synthetase (AspRS/AsnRS) class II core domain.  Assignment to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure and the presence of three characteristic sequence motifs in the core domain. This family includes AsnRS as well as...; Region: AsxRS_core; cd00776
936154001389	homodimer interface [polypeptide binding]; other site
936154001390	motif 1; other site
936154001391	motif 2; other site
936154001392	active site
936154001393	motif 3; other site
936154001394	nuc_hydro: Nucleoside hydrolases. Nucleoside hydrolases cleave the N-glycosidic bond in nucleosides generating ribose and the respective base. These enzymes vary in their substrate specificity.  This group contains eukaryotic, bacterial and archeal...; Region: nuc_hydro; cl00226
936154001395	glmZ(sRNA)-inactivating NTPase; Provisional; Region: PRK05416
936154001396	conserved hypothetical protein, cofD-related; Region: CofD_related; TIGR01826
936154001397	Family of CofD-like proteins and proteins related to YvcK; Region: CofD_YvcK; cd07044
936154001398	dimer interface [polypeptide binding]; other site
936154001399	phosphate binding site [ion binding]; other site
936154001400	Sporulation Regulator WhiA N terminal; Region: WhiA_N; pfam10298
936154001401	Sporulation Regulator WhiA C terminal domain; Region: HTH_WhiA; pfam02650
936154001402	Peptidase family C69; Region: Peptidase_C69; pfam03577
936154001403	ABC-type metal ion transport system, periplasmic component/surface adhesin [Inorganic ion transport and metabolism]; Region: LraI; COG0803
936154001404	Metal binding protein AcdA.  These proteins have been shown to function in the ABC uptake of Zn2+ and Mn2+ and in competence for genetic transformation and adhesion. The AcdA proteins belong to the TroA superfamily of helical backbone metal receptor...; Region: AdcA; cd01017
936154001405	metal binding site [ion binding]; metal-binding site
936154001406	YodA lipocalin-like domain; Region: YodA; pfam09223
936154001407	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
936154001408	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
936154001409	DNA-binding site [nucleotide binding]; DNA binding site
936154001410	UTRA domain; Region: UTRA; pfam07702
936154001411	SIS (Sugar ISomerase) domain repeat 1 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_1; cd05008
936154001412	active site
936154001413	AgaS-like protein. AgaS contains a SIS (Sugar ISomerase) domain which is found in many phosphosugar isomerases and phosphosugar binding proteins. AgaS is a putative isomerase in Escherichia coli. It is similar to the glucosamine-6-phosphate synthases; Region: SIS_AgaS_like; cd05010
936154001414	putative active site [active]
936154001415	1-phosphofructokinase (FruK), minor 6-phosphofructokinase (pfkB) and related sugar kinases. FruK plays an important role in the predominant pathway for fructose utilisation.This group also contains tagatose-6-phophate kinase, an enzyme of the tagatose...; Region: FruK_PfkB_like; cd01164
936154001416	tagatose-6-phosphate kinase; Region: lacC; TIGR01231
936154001417	putative substrate binding site [chemical binding]; other site
936154001418	putative ATP binding site [chemical binding]; other site
936154001419	tagatose 1,6-diphosphate aldolase; Reviewed; Region: PRK12399
936154001420	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
936154001421	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
936154001422	DNA-binding site [nucleotide binding]; DNA binding site
936154001423	The UbiC transcription regulator-associated (UTRA) domain is a conserved ligand-binding domain; Region: UTRA; smart00866
936154001424	Glycosyl hydrolases family 35; Region: Glyco_hydro_35; pfam01301
936154001425	PTS_IIB, PTS system, Mannose/sorbose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_man; cd00001
936154001426	active site
936154001427	phosphorylation site [posttranslational modification]
936154001428	Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIC [Carbohydrate transport and metabolism]; Region: ManY; COG3715
936154001429	PTS system mannose/fructose/sorbose family IID component; Region: EIID-AGA; pfam03613
936154001430	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cd00006
936154001431	active pocket/dimerization site; other site
936154001432	active site
936154001433	phosphorylation site [posttranslational modification]
936154001434	50S ribosomal protein L31 type B; Reviewed; Region: rpmE2; PRK01678
936154001435	DHH family; Region: DHH; pfam01368
936154001436	Exopolyphosphatase-related proteins [General function prediction only]; Region: COG0618
936154001437	DHHA1 domain; Region: DHHA1; pfam02272
936154001438	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
936154001439	putative S-transferase; Provisional; Region: PRK11752
936154001440	GST_N family, Ure2p-like subfamily; composed of the Saccharomyces cerevisiae Ure2p and related GSTs. Ure2p is a regulator for nitrogen catabolism in yeast. It represses the expression of several gene products involved in the use of poor nitrogen sources...; Region: GST_N_Ure2p_like; cd03048
936154001441	C-terminal domain interface [polypeptide binding]; other site
936154001442	GSH binding site (G-site) [chemical binding]; other site
936154001443	dimer interface [polypeptide binding]; other site
936154001444	C-terminal, alpha helical domain of the Glutathione S-transferase family; Region: GST_C_family; cl02776
936154001445	N-terminal domain interface [polypeptide binding]; other site
936154001446	dimer interface [polypeptide binding]; other site
936154001447	substrate binding pocket (H-site) [chemical binding]; other site
936154001448	Adenosine deaminase [Nucleotide transport and metabolism]; Region: Add; COG1816
936154001449	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
936154001450	active site
936154001451	flavodoxin; Validated; Region: PRK07308
936154001452	hypothetical protein; Provisional; Region: PRK07248
936154001453	CLC voltage-gated chloride channel. The ClC chloride channels catalyse the selective flow of Cl- ions across cell membranes, thereby regulating electrical excitation in skeletal muscle and the flow of salt and water across epithelial barriers. This...; Region: Voltage_gated_ClC; cl02915
936154001454	Chloride channel protein EriC [Inorganic ion transport and metabolism]; Region: EriC; COG0038
936154001455	Cl- selectivity filter; other site
936154001456	Cl- binding residues [ion binding]; other site
936154001457	pore gating glutamate residue; other site
936154001458	dimer interface [polypeptide binding]; other site
936154001459	50S ribosomal protein L19; Provisional; Region: rplS; PRK05338
936154001460	KDPG and KHG aldolase; Region: Aldolase; cl17259
936154001461	Bacterial cell division membrane protein [Cell division and chromosome partitioning]; Region: FtsW; COG0772
936154001462	Predicted phosphatases [General function prediction only]; Region: Gph; COG0546
936154001463	DNA gyrase subunit B; Validated; Region: gyrB; PRK05644
936154001464	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
936154001465	Mg2+ binding site [ion binding]; other site
936154001466	G-X-G motif; other site
936154001467	TopoIIA_Trans_DNA_gyrase: Transducer domain, having a ribosomal S5 domain 2-like fold, of the type found in proteins of the type IIA family of DNA topoisomerases similar to the B subunits of E. coli DNA gyrase and E. coli Topoisomerase IV which are; Region: TopoII_Trans_DNA_gyrase; cd00822
936154001468	anchoring element; other site
936154001469	dimer interface [polypeptide binding]; other site
936154001470	ATP binding site [chemical binding]; other site
936154001471	TOPRIM_TopoIIA_GyrB: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in proteins of the type IIA family of DNA topoisomerases similar to the Escherichia coli GyrB subunit. TopoIIA enzymes cut both strands of the...; Region: TOPRIM_TopoIIA_GyrB; cd03366
936154001472	active site
936154001473	putative metal-binding site [ion binding]; other site
936154001474	DNA gyrase B subunit, carboxyl terminus; Region: DNA_gyraseB_C; pfam00986
936154001475	septation ring formation regulator EzrA; Provisional; Region: PRK04778
936154001476	phosphoserine phosphatase SerB; Region: serB; TIGR00338
936154001477	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
936154001478	motif II; other site
936154001479	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
936154001480	This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_10; cd07251
936154001481	Protein of unknown function (DUF1697); Region: DUF1697; pfam08002
936154001482	Protein of unknown function (DUF1694); Region: DUF1694; pfam07997
936154001483	enolase; Provisional; Region: eno; PRK00077
936154001484	Enolase: Enolases are homodimeric enzymes that catalyse the reversible dehydration of 2-phospho-D-glycerate to phosphoenolpyruvate as part of the glycolytic and gluconeogenesis pathways. The reaction is facilitated by the presence of metal ions; Region: enolase; cd03313
936154001485	dimer interface [polypeptide binding]; other site
936154001486	metal binding site [ion binding]; metal-binding site
936154001487	substrate binding pocket [chemical binding]; other site
936154001488	putative acyltransferase; Provisional; Region: PRK05790
936154001489	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
936154001490	dimer interface [polypeptide binding]; other site
936154001491	active site
936154001492	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2964
936154001493	YheO-like PAS domain; Region: PAS_6; pfam08348
936154001494	HTH domain; Region: HTH_22; pfam13309
936154001495	YjgF, YER057c, and UK114 belong to a large family of proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no...; Region: YjgF_YER057c_UK114_family; cd00448
936154001496	homotrimer interaction site [polypeptide binding]; other site
936154001497	putative active site [active]
936154001498	Phosphotransferase system, fructose-specific IIC component [Carbohydrate transport and metabolism]; Region: FruA; COG1299
936154001499	Phosphotransferase system, EIIC; Region: PTS_EIIC_2; pfam13303
936154001500	V-type ATP synthase subunit I; Validated; Region: PRK05771
936154001501	V-type ATP synthase subunit I; Validated; Region: PRK05771
936154001502	V-type ATP synthase subunit K; Validated; Region: PRK06558
936154001503	ATP synthase subunit C; Region: ATP-synt_C; pfam00137
936154001504	Archaeal/vacuolar-type H+-ATPase subunit C [Energy production and conversion]; Region: NtpC; COG1527
936154001505	V-type ATP synthase subunit C; Provisional; Region: PRK01198; cl00660
936154001506	V-type ATP synthase subunit A; Provisional; Region: PRK04192
936154001507	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
936154001508	V/A-type ATP synthase catalytic subunit A. These ATPases couple ATP hydrolysis to the build up of a H+ gradient, but V-type ATPases do not catalyze the reverse reaction.  The Vacuolar (V-type) ATPase is found in the membranes of vacuoles, the golgi...; Region: V_A-ATPase_A; cd01134
936154001509	Walker A motif/ATP binding site; other site
936154001510	Walker B motif; other site
936154001511	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
936154001512	V-type ATP synthase subunit B; Provisional; Region: PRK04196
936154001513	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
936154001514	V/A-type ATP synthase (non-catalytic) subunit B. These ATPases couple ATP hydrolysis to the build up of a H+ gradient, but V-type ATPases do not catalyze the reverse reaction. The Vacuolar (V-type) ATPase is found in the membranes of vacuoles, the golgi...; Region: V_A-ATPase_B; cd01135
936154001515	Walker A motif homologous position; other site
936154001516	Walker B motif; other site
936154001517	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
936154001518	ATP synthase subunit D; Region: ATP-synt_D; cl00613
936154001519	This family contains NADPH-dependent flavin reductase and oxygen-insensitive nitroreductase. These enzymes are homodimeric flavoproteins that contain one FMN per monomer as a cofactor. Flavin reductase catalyzes the reduction of flavin by using NADPH as...; Region: NfsA_FRP; cd02146
936154001520	dimer interface [polypeptide binding]; other site
936154001521	FMN binding site [chemical binding]; other site
936154001522	NADPH bind site [chemical binding]; other site
936154001523	Protein of unknown function (DUF1211); Region: DUF1211; cl01421
936154001524	Predicted membrane protein [Function unknown]; Region: COG4708
936154001525	NAD-dependent DNA ligase LigA; Validated; Region: ligA; PRK07956
936154001526	NAD+ dependent DNA ligase adenylation domain. DNA ligases catalyze the crucial step of joining the breaks in duplex DNA during DNA replication, repair and recombination, utilizing either ATP or NAD(+) as a cofactor, but using the same basic reaction...; Region: LIGANc; cd00114
936154001527	nucleotide binding pocket [chemical binding]; other site
936154001528	K-X-D-G motif; other site
936154001529	catalytic site [active]
936154001530	NAD-dependent DNA ligase OB-fold domain; Region: DNA_ligase_OB; pfam03120
936154001531	NAD-dependent DNA ligase C4 zinc finger domain; Region: DNA_ligase_ZBD; pfam03119
936154001532	Breast Cancer Suppressor Protein (BRCA1), carboxy-terminal domain. The BRCT domain is found within many DNA damage repair and cell cycle checkpoint proteins. The unique diversity of this domain superfamily allows BRCT modules to interact forming homo...; Region: BRCT; cd00027
936154001533	Dimer interface [polypeptide binding]; other site
936154001534	BRCT sequence motif; other site
936154001535	putative lipid kinase; Reviewed; Region: PRK13055
936154001536	Diacylglycerol kinase catalytic domain; Region: DAGK_cat; pfam00781
936154001537	Family 41 Carbohydrate-Binding Module from pullulanase-like enzymes; Region: CBM41_pullulanase; cd10315
936154001538	carbohydrate binding site [chemical binding]; other site
936154001539	Early set domain associated with the catalytic domain of pullulanase (also called dextrinase and alpha-dextrin endo-1,6-alpha glucosidase); Region: E_set_Pullulanase; cd02860
936154001540	Alpha amylase catalytic domain found in Pullulanase (also called dextrinase; alpha-dextrin endo-1,6-alpha glucosidase), limit dextrinase, and related proteins; Region: AmyAc_Pullulanase_LD-like; cd11341
936154001541	Ca binding site [ion binding]; other site
936154001542	active site
936154001543	catalytic site [active]
936154001544	glycogen branching enzyme; Provisional; Region: PRK12313
936154001545	N-terminal Early set domain associated with the catalytic domain of prokaryotic glycogen branching enzyme; Region: E_set_GBE_prok_N; cd02855
936154001546	Alpha amylase catalytic domain found in the Glycogen branching enzyme (also called 1,4-alpha-glucan branching enzyme); Region: AmyAc_Glg_BE; cd11322
936154001547	active site
936154001548	catalytic site [active]
936154001549	Alpha amylase, C-terminal all-beta domain; Region: Alpha-amylase_C; pfam02806
936154001550	glucose-1-phosphate adenylyltransferase; Provisional; Region: glgC; PRK05293
936154001551	ADP-glucose pyrophosphorylase is involved in the biosynthesis of glycogen or starch; Region: ADP_Glucose_PP; cd02508
936154001552	ligand binding site; other site
936154001553	oligomer interface; other site
936154001554	Glucose-1-phosphate adenylyltransferase, C-terminal Left-handed parallel beta helix (LbH) domain: Glucose-1-phosphate adenylyltransferase is also known as ADP-glucose synthase or ADP-glucose pyrophosphorylase. It catalyzes the first committed and...; Region: LbH_G1P_AT_C; cd04651
936154001555	dimer interface [polypeptide binding]; other site
936154001556	N-terminal domain interface [polypeptide binding]; other site
936154001557	sulfate 1 binding site; other site
936154001558	potential frameshift: common BLAST hit: gi|225870294|ref|YP_002746241.1| glycogen biosynthesis protein
936154001559	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
936154001560	active site
936154001561	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
936154001562	Glucose-1-phosphate adenylyltransferase, C-terminal Left-handed parallel beta helix (LbH) domain: Glucose-1-phosphate adenylyltransferase is also known as ADP-glucose synthase or ADP-glucose pyrophosphorylase. It catalyzes the first committed and...; Region: LbH_G1P_AT_C; cd04651
936154001563	dimer interface [polypeptide binding]; other site
936154001564	N-terminal domain interface [polypeptide binding]; other site
936154001565	sulfate 1 binding site; other site
936154001566	glycogen synthase; Provisional; Region: glgA; PRK00654
936154001567	This family is most closely related to the GT1 family of glycosyltransferases. Glycogen synthase catalyzes the formation and elongation of the alpha-1,4-glucose backbone using ADP-glucose, the second and key step of glycogen biosynthesis. This family...; Region: GT1_Glycogen_synthase_DULL1_like; cd03791
936154001568	ADP-binding pocket [chemical binding]; other site
936154001569	homodimer interface [polypeptide binding]; other site
936154001570	This is a family of oligosaccharide phosphorylases. It includes yeast and mammalian glycogen phosphorylases, plant starch/glucan phosphorylase, as well as the maltodextrin phosphorylases of bacteria. The members of this family catalyze the breakdown of...; Region: GT1_Glycogen_Phosphorylase; cd04300
936154001571	homodimer interface [polypeptide binding]; other site
936154001572	glycogen/starch/alpha-glucan phosphorylases; Region: P_ylase; TIGR02093
936154001573	active site pocket [active]
936154001574	F0F1 ATP synthase subunit C; Provisional; Region: PRK13467
936154001575	F0F1 ATP synthase subunit A; Validated; Region: PRK05815
936154001576	F0F1-type ATP synthase, subunit a [Energy production and conversion]; Region: AtpB; COG0356
936154001577	F0F1-type ATP synthase, subunit b [Energy production and conversion]; Region: AtpF; COG0711
936154001578	F0F1 ATP synthase subunit B; Validated; Region: PRK05759
936154001579	F0F1 ATP synthase subunit delta; Validated; Region: PRK05758
936154001580	ATP synthase delta (OSCP) subunit; Region: OSCP; pfam00213
936154001581	F0F1 ATP synthase subunit alpha; Validated; Region: PRK09281
936154001582	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
936154001583	F1 ATP synthase alpha, central domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a proton gradient to...; Region: F1_ATPase_alpha; cd01132
936154001584	beta subunit interaction interface [polypeptide binding]; other site
936154001585	Walker A motif; other site
936154001586	ATP binding site [chemical binding]; other site
936154001587	Walker B motif; other site
936154001588	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
936154001589	F0F1 ATP synthase subunit beta; Validated; Region: PRK09280
936154001590	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
936154001591	F1 ATP synthase beta subunit, nucleotide-binding domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a...; Region: F1-ATPase_beta; cd01133
936154001592	alpha subunit interaction interface [polypeptide binding]; other site
936154001593	Walker A motif; other site
936154001594	ATP binding site [chemical binding]; other site
936154001595	Walker B motif; other site
936154001596	inhibitor binding site; inhibition site
936154001597	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
936154001598	F0F1 ATP synthase subunit epsilon; Validated; Region: atpC; PRK00571
936154001599	mitochondrial ATP synthase delta subunit; Region: F1-ATPase_delta; cd12152
936154001600	gamma subunit interface [polypeptide binding]; other site
936154001601	epsilon subunit interface [polypeptide binding]; other site
936154001602	LBP interface [polypeptide binding]; other site
936154001603	UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Region: murA; TIGR01072
936154001604	UDP-N-acetylglucosamine enolpyruvyl transferase catalyzes enolpyruvyl transfer as part of the first step in the biosynthesis of peptidoglycan, a component of the bacterial cell wall. The reaction is phosphoenolpyruvate + UDP-N-acetyl-D-glucosamine =...; Region: UdpNAET; cd01555
936154001605	hinge; other site
936154001606	active site
936154001607	DNA-directed RNA polymerase subunit beta; Region: EpuA; pfam11772
936154001608	DNA/RNA non-specific endonuclease; Region: Endonuclease_NS; smart00892
936154001609	DNA/RNA non-specific endonuclease; Region: Endonuclease_NS; pfam01223
936154001610	phenylalanyl-tRNA synthetase subunit alpha; Validated; Region: pheS; PRK00488
936154001611	Aminoacyl tRNA synthetase class II, N-terminal domain; Region: Phe_tRNA-synt_N; pfam02912
936154001612	Phenylalanyl-tRNA synthetase (PheRS) alpha chain catalytic core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure and the presence of three characteristic sequence motifs. This domain is primarily responsible...; Region: PheRS_alpha_core; cd00496
936154001613	dimer interface [polypeptide binding]; other site
936154001614	motif 1; other site
936154001615	active site
936154001616	motif 2; other site
936154001617	motif 3; other site
936154001618	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
936154001619	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
936154001620	Coenzyme A binding pocket [chemical binding]; other site
936154001621	phenylalanyl-tRNA synthetase subunit beta; Reviewed; Region: pheT; PRK00629
936154001622	tRNA-binding-domain-containing prokaryotic phenylalanly tRNA synthetase (PheRS) beta chain.  PheRS aminoacylate phenylalanine transfer RNAs (tRNAphe). PheRSs belong structurally to class II aminoacyl tRNA synthetases (aaRSs) but, as they aminoacylate...; Region: tRNA_bind_bactPheRS; cd02796
936154001623	putative tRNA-binding site [nucleotide binding]; other site
936154001624	B3/4 domain; Region: B3_4; pfam03483
936154001625	tRNA synthetase B5 domain; Region: B5; smart00874
936154001626	Phenylalanyl-tRNA synthetase (PheRS) beta chain core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure. While class II aaRSs generally aminoacylate the 3'-OH ribose of the appropriate tRNA,  PheRS is an...; Region: PheRS_beta_core; cd00769
936154001627	dimer interface [polypeptide binding]; other site
936154001628	motif 1; other site
936154001629	motif 3; other site
936154001630	motif 2; other site
936154001631	Ferredoxin-fold anticodon binding domain; Region: FDX-ACB; pfam03147
936154001632	ribokinase/pfkB superfamily: Kinases that accept a wide variety of substrates, including carbohydrates and aromatic small molecules, all are phosphorylated at a hydroxyl group. The superfamily includes ribokinase, fructokinase, ketohexokinase; Region: ribokinase_pfkB_like; cl00192
936154001633	substrate binding site [chemical binding]; other site
936154001634	ATP binding site [chemical binding]; other site
936154001635	OsmC-like protein; Region: OsmC; pfam02566
936154001636	potential frameshift: common BLAST hit: gi|222152844|ref|YP_002562021.1| permease
936154001637	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
936154001638	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
936154001639	Walker A/P-loop; other site
936154001640	ATP binding site [chemical binding]; other site
936154001641	ABC transporter; Region: ABC_tran; pfam00005
936154001642	Q-loop/lid; other site
936154001643	ABC transporter signature motif; other site
936154001644	Walker B; other site
936154001645	D-loop; other site
936154001646	Putative neutral zinc metallopeptidase; Region: Zn_peptidase; pfam04228
936154001647	Predicted metalloprotease [General function prediction only]; Region: COG2321
936154001648	ATP-dependent nuclease subunit B; Region: rexB_recomb; TIGR02774
936154001649	PD-(D/E)XK nuclease superfamily; Region: PDDEXK_1; pfam12705
936154001650	helicase-exonuclease AddAB, AddA subunit, Firmicutes type; Region: addA_Gpos; TIGR02785
936154001651	Family description; Region: UvrD_C_2; pfam13538
936154001652	PD-(D/E)XK nuclease superfamily; Region: PDDEXK_1; pfam12705
936154001653	transaminase; Validated; Region: PRK07324
936154001654	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
936154001655	pyridoxal 5'-phosphate binding site [chemical binding]; other site
936154001656	homodimer interface [polypeptide binding]; other site
936154001657	catalytic residue [active]
936154001658	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
936154001659	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
936154001660	substrate binding pocket [chemical binding]; other site
936154001661	membrane-bound complex binding site; other site
936154001662	hinge residues; other site
936154001663	30S ribosomal protein S21; Reviewed; Region: rpsU; PRK00270
936154001664	Large-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscL; COG1970
936154001665	large-conductance mechanosensitive channel; Reviewed; Region: mscL; PRK00567
936154001666	CHC2 zinc finger; Region: zf-CHC2; pfam01807
936154001667	DNA primase; Validated; Region: dnaG; PRK05667
936154001668	DNA primase catalytic core, N-terminal domain; Region: Toprim_N; pfam08275
936154001669	TOPRIM_DnaG_primases: The topoisomerase-primase (TORPIM) nucleotidyl transferase/hydrolase domain found in the active site regions of proteins similar to Escherichia coli DnaG. Primases synthesize RNA primers for the initiation of DNA replication. DnaG...; Region: TOPRIM_DnaG_primases; cd03364
936154001670	active site
936154001671	metal binding site [ion binding]; metal-binding site
936154001672	interdomain interaction site; other site
936154001673	DnaB-helicase binding domain of primase; Region: DnaB_bind; pfam10410
936154001674	Sigma-70 factor, region 1.2; Region: Sigma70_r1_2; pfam00140
936154001675	RNA polymerase sigma factor RpoD, C-terminal domain; Region: RpoD_Cterm; TIGR02393
936154001676	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
936154001677	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
936154001678	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
936154001679	DNA binding residues [nucleotide binding]
936154001680	Predicted metal-sulfur cluster biosynthetic enzyme [General function prediction only]; Region: PaaD; COG2151
936154001681	dTDP-6-deoxy-L-lyxo-4-hexulose reductase and related proteins, extended (e) SDRs; Region: dTDP_HR_like_SDR_e; cd05254
936154001682	RmlD substrate binding domain; Region: RmlD_sub_bind; pfam04321
936154001683	NADP binding site [chemical binding]; other site
936154001684	active site
936154001685	putative substrate binding site [chemical binding]; other site
936154001686	This family is most closely related to the GT1 family of glycosyltransferases. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can...; Region: GT1_like_6; cd04955
936154001687	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
936154001688	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
936154001689	Subfamily of Glycosyltransferase Family GT2 of unknown function; Region: GT_2_like_d; cd04196
936154001690	Probable Catalytic site; other site
936154001691	ABC-type polysaccharide/polyol phosphate export systems, permease component [Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: TagG; COG1682
936154001692	ABC-2 type transporter; Region: ABC2_membrane; pfam01061
936154001693	ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: TagH; COG1134
936154001694	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
936154001695	ABC transporter signature motif; other site
936154001696	Walker B; other site
936154001697	D-loop; other site
936154001698	H-loop/switch region; other site
936154001699	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
936154001700	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
936154001701	Rhamnan synthesis protein F; Region: RgpF; pfam05045
936154001702	Sulfatase; Region: Sulfatase; cl17466
936154001703	conserved hypothetical integral membrane protein; Region: TIGR03766
936154001704	undecaprenyl phosphate 4-deoxy-4-formamido-L-arabinose transferase; Provisional; Region: PRK10714
936154001705	Bacterial DPM1_like enzymes are related to eukaryotic DPM1; Region: DPM1_like_bac; cd04187
936154001706	Ligand binding site; other site
936154001707	Putative Catalytic site; other site
936154001708	DXD motif; other site
936154001709	Predicted membrane protein [Function unknown]; Region: COG2246
936154001710	GtrA-like protein; Region: GtrA; pfam04138
936154001711	GBS Bsp-like repeat; Region: GBS_Bsp-like; pfam08481
936154001712	GBS Bsp-like repeat; Region: GBS_Bsp-like; pfam08481
936154001713	GBS Bsp-like repeat; Region: GBS_Bsp-like; pfam08481
936154001714	GBS Bsp-like repeat; Region: GBS_Bsp-like; pfam08481
936154001715	N-acetylmuramoyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: AmiC; COG0860
936154001716	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696
936154001717	active site
936154001718	metal binding site [ion binding]; metal-binding site
936154001719	peptidase T; Region: peptidase-T; TIGR01882
936154001720	M20 Peptidase T specifically cleaves tripeptides; Region: M20_peptT; cd03892
936154001721	metal binding site [ion binding]; metal-binding site
936154001722	dimer interface [polypeptide binding]; other site
936154001723	Ferredoxin [Energy production and conversion]; Region: Fer; COG1141
936154001724	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
936154001725	cytidylate kinase; Provisional; Region: cmk; PRK00023
936154001726	Cytidine monophosphate kinase (CMPK) catalyzes the reversible phosphorylation of cytidine monophosphate (CMP) to produce cytidine diphosphate (CDP), using ATP as the preferred phosphoryl donor; Region: CMPK; cd02020
936154001727	CMP-binding site; other site
936154001728	The sites determining sugar specificity; other site
936154001729	Translation initiation factor IF-3, C-terminal domain; Region: IF3_C; pfam00707
936154001730	50S ribosomal protein L35; Reviewed; Region: rpmI; PRK00172
936154001731	Ribosomal protein L20; Region: Ribosomal_L20; cd07026
936154001732	23S rRNA binding site [nucleotide binding]; other site
936154001733	L21 binding site [polypeptide binding]; other site
936154001734	L13 binding site [polypeptide binding]; other site
936154001735	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily [Cell envelope biogenesis, outer membrane]; Region: MdoB; COG1368
936154001736	Sulfatase; Region: Sulfatase; pfam00884
936154001737	Predicted SAM-dependent methyltransferases [General function prediction only]; Region: COG1092
936154001738	Middle domain of the SAM-dependent methyltransferase RlmI and related proteins; Region: RlmI_M_like; cd11572
936154001739	putative RNA binding site [nucleotide binding]; other site
936154001740	Methyltransferase domain; Region: Methyltransf_26; pfam13659
936154001741	3-dehydroquinate dehydratase [Amino acid transport and metabolism]; Region: AroD; COG0710
936154001742	Type I 3-dehydroquinase, (3-dehydroquinate dehydratase or DHQase); Region: DHQase_I; cd00502
936154001743	active site
936154001744	catalytic residue [active]
936154001745	dimer interface [polypeptide binding]; other site
936154001746	Chorismate synthase [Amino acid transport and metabolism]; Region: AroC; COG0082
936154001747	Chorismase synthase, the enzyme catalyzing the final step of the shikimate pathway; Region: Chorismate_synthase; cd07304
936154001748	Tetramer interface [polypeptide binding]; other site
936154001749	active site
936154001750	FMN-binding site [chemical binding]; other site
936154001751	hypothetical protein; Provisional; Region: PRK13676
936154001752	glutathione reductase; Validated; Region: PRK06116
936154001753	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
936154001754	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
936154001755	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
936154001756	folylpolyglutamate synthase/dihydrofolate synthase; Region: folC; TIGR01499
936154001757	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
936154001758	Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes [Amino acid transport and metabolism]; Region: NifS; COG1104
936154001759	cysteine desulfurase NifS; Region: FeS_nifS; TIGR03402
936154001760	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
936154001761	catalytic residue [active]
936154001762	thiamine biosynthesis protein ThiI; Provisional; Region: PRK01565
936154001763	THUMP domain of thiamine biosynthesis protein ThiI; Region: THUMP_ThiI; cd11716
936154001764	ThiI is required for thiazole synthesis in the thiamine biosynthesis pathway. It belongs to the Adenosine Nucleotide Hydrolysis suoerfamily and predicted to bind to Adenosine nucleotide; Region: ThiI; cd01712
936154001765	Ligand Binding Site [chemical binding]; other site
936154001766	Bacterial capsule synthesis protein PGA_cap; Region: PGA_cap; smart00854
936154001767	CapA and related proteins, metallophosphatase domain; Region: MPP_CapA; cd07381
936154001768	putative active site [active]
936154001769	putative metal binding site [ion binding]; other site
936154001770	50S ribosomal protein L21; Validated; Region: rplU; PRK05573
936154001771	Predicted ribosomal protein [Translation, ribosomal structure and biogenesis]; Region: COG2868
936154001772	50S ribosomal protein L27; Validated; Region: rpmA; PRK05435
936154001773	Transcriptional regulator [Transcription]; Region: LysR; COG0583
936154001774	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
936154001775	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
936154001776	dimerization interface [polypeptide binding]; other site
936154001777	lipoprotein signal peptidase; Provisional; Region: PRK14797
936154001778	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
936154001779	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
936154001780	RNA binding surface [nucleotide binding]; other site
936154001781	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
936154001782	active site
936154001783	Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase [Nucleotide transport and metabolism]; Region: PyrR; COG2065
936154001784	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
936154001785	active site
936154001786	uracil transporter; Provisional; Region: PRK10720
936154001787	aspartate carbamoyltransferase catalytic subunit; Provisional; Region: pyrB; PRK00856
936154001788	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
936154001789	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
936154001790	carbamoyl phosphate synthase small subunit; Reviewed; Region: PRK12564
936154001791	Carbamoyl-phosphate synthase small chain, CPSase domain; Region: CPSase_sm_chain; smart01097
936154001792	Small chain of the glutamine-dependent form of carbamoyl phosphate synthase, CPSase II; Region: GATase1_CPSase; cd01744
936154001793	catalytic site [active]
936154001794	subunit interface [polypeptide binding]; other site
936154001795	carbamoyl phosphate synthase large subunit; Reviewed; Region: carB; PRK05294
936154001796	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
936154001797	Carbamoyl-phosphate synthase L chain, ATP binding domain; Region: CPSase_L_D2; pfam02786
936154001798	Carbamoyl-phosphate synthetase large chain, oligomerisation domain; Region: CPSase_L_D3; pfam02787
936154001799	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
936154001800	ATP-grasp domain; Region: ATP-grasp_4; cl17255
936154001801	Methylglyoxal synthase-like domain from type II glutamine-dependent carbamoyl phosphate synthetase (CSP). CSP, a CarA and CarB heterodimer, catalyzes the production of carbamoyl phosphate which is subsequently employed in the metabolic pathways...; Region: MGS_CPS_II; cd01424
936154001802	IMP binding site; other site
936154001803	dimer interface [polypeptide binding]; other site
936154001804	interdomain contacts; other site
936154001805	partial ornithine binding site; other site
936154001806	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
936154001807	HlyD family secretion protein; Region: HlyD_3; pfam13437
936154001808	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
936154001809	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
936154001810	Walker A/P-loop; other site
936154001811	ATP binding site [chemical binding]; other site
936154001812	Q-loop/lid; other site
936154001813	ABC transporter signature motif; other site
936154001814	Walker B; other site
936154001815	D-loop; other site
936154001816	H-loop/switch region; other site
936154001817	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
936154001818	ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms]; Region: SalY; COG0577
936154001819	FtsX-like permease family; Region: FtsX; pfam02687
936154001820	SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335
936154001821	30S ribosomal protein S16; Reviewed; Region: rpsP; PRK00040
936154001822	Predicted RNA-binding protein (contains KH domain) [General function prediction only]; Region: COG1837
936154001823	KH domain; Region: KH_4; pfam13083
936154001824	G-X-X-G motif; other site
936154001825	accessory Sec system glycosyltransferase GtfB; Region: TIGR02919
936154001826	accessory Sec system glycosylation protein GtfA; Region: TIGR02918
936154001827	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
936154001828	16S rRNA-processing protein RimM; Provisional; Region: rimM; PRK00122
936154001829	RimM N-terminal domain; Region: RimM; pfam01782
936154001830	PRC-barrel domain; Region: PRC; pfam05239
936154001831	tRNA (guanine-N(1)-)-methyltransferase; Reviewed; Region: trmD; PRK00026
936154001832	Thioredoxin reductase [Posttranslational modification, protein turnover, chaperones]; Region: TrxB; COG0492
936154001833	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
936154001834	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
936154001835	Predicted membrane protein, putative toxin regulator [General function prediction only]; Region: PfoR; COG3641
936154001836	Phosphotransferase system, EIIC; Region: PTS_EIIC_2; pfam13303
936154001837	2-dehydropantoate 2-reductase; Reviewed; Region: PRK06522
936154001838	Ketopantoate reductase PanE/ApbA; Region: ApbA; pfam02558
936154001839	Ketopantoate reductase PanE/ApbA C terminal; Region: ApbA_C; pfam08546
936154001840	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
936154001841	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; cl17531
936154001842	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
936154001843	Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB) [Carbohydrate transport and metabolism]; Region: FruK; COG1105
936154001844	1-phosphofructokinase (FruK), minor 6-phosphofructokinase (pfkB) and related sugar kinases. FruK plays an important role in the predominant pathway for fructose utilisation.This group also contains tagatose-6-phophate kinase, an enzyme of the tagatose...; Region: FruK_PfkB_like; cd01164
936154001845	putative substrate binding site [chemical binding]; other site
936154001846	putative ATP binding site [chemical binding]; other site
936154001847	PTS system 2-O-a-mannosyl-D-glycerate specific transporter subunit IIABC; Provisional; Region: PRK09765
936154001848	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
936154001849	active site
936154001850	phosphorylation site [posttranslational modification]
936154001851	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
936154001852	active site
936154001853	P-loop; other site
936154001854	phosphorylation site [posttranslational modification]
936154001855	Phosphotransferase system, fructose-specific IIC component [Carbohydrate transport and metabolism]; Region: FruA; COG1299
936154001856	potential frameshift: common BLAST hit: gi|195978223|ref|YP_002123467.1| probable N-acetylmuramidase precursor
936154001857	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase; Region: Glucosaminidase; cl17361
936154001858	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase; Region: Glucosaminidase; cl17361
936154001859	Muramidase (flagellum-specific) [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FlgJ; COG1705
936154001860	Protein of unknown function (DUF1149); Region: DUF1149; pfam06619
936154001861	EDD domain protein, DegV family; Region: DegV; TIGR00762
936154001862	Uncharacterized protein, DegV family COG1307; Region: DegV; pfam02645
936154001863	dihydrodipicolinate reductase; Provisional; Region: PRK00048
936154001864	Dihydrodipicolinate reductase, N-terminus; Region: DapB_N; pfam01113
936154001865	Dihydrodipicolinate reductase, C-terminus; Region: DapB_C; pfam05173
936154001866	tRNA CCA-pyrophosphorylase; Provisional; Region: PRK13299
936154001867	Nucleotidyltransferase (NT) domain of ClassII CCA-adding enzymes; Region: NT_ClassII-CCAase; cd05398
936154001868	active site
936154001869	NTP binding site [chemical binding]; other site
936154001870	metal binding triad [ion binding]; metal-binding site
936154001871	Probable RNA and SrmB- binding site of polymerase A; Region: PolyA_pol_RNAbd; pfam12627
936154001872	tRNA nucleotidyltransferase domain 2 putative; Region: tRNA_NucTran2_2; pfam13735
936154001873	ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only]; Region: Uup; COG0488
936154001874	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
936154001875	Walker A/P-loop; other site
936154001876	ATP binding site [chemical binding]; other site
936154001877	Q-loop/lid; other site
936154001878	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
936154001879	ABC transporter; Region: ABC_tran_2; pfam12848
936154001880	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
936154001881	Acetyltransferases [General function prediction only]; Region: RimI; COG0456
936154001882	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
936154001883	Coenzyme A binding pocket [chemical binding]; other site
936154001884	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
936154001885	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
936154001886	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
936154001887	Walker A/P-loop; other site
936154001888	ATP binding site [chemical binding]; other site
936154001889	Q-loop/lid; other site
936154001890	ABC transporter signature motif; other site
936154001891	Walker B; other site
936154001892	D-loop; other site
936154001893	H-loop/switch region; other site
936154001894	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
936154001895	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
936154001896	ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Region: ABCC_Glucan_exporter_like; cd03254
936154001897	Walker A/P-loop; other site
936154001898	ATP binding site [chemical binding]; other site
936154001899	Q-loop/lid; other site
936154001900	ABC transporter signature motif; other site
936154001901	Walker B; other site
936154001902	D-loop; other site
936154001903	H-loop/switch region; other site
936154001904	glutamate dehydrogenase; Provisional; Region: PRK09414
936154001905	Glu/Leu/Phe/Val dehydrogenase, dimerisation domain; Region: ELFV_dehydrog_N; pfam02812
936154001906	NAD(P) binding domain of glutamate dehydrogenase, subgroup 2; Region: NAD_bind_2_Glu_DH; cd05313
936154001907	NAD(P) binding site [chemical binding]; other site
936154001908	Polypeptide or peptide deformylase; a family of metalloenzymes that catalyzes the removal of the N-terminal formyl group in a growing polypeptide chain following translation initiation during protein synthesis in prokaryotes. These enzymes utilize Fe(II)...; Region: Pep_deformylase; cd00487
936154001909	active site
936154001910	catalytic residues [active]
936154001911	metal binding site [ion binding]; metal-binding site
936154001912	potential frameshift: common BLAST hit: gi|251782243|ref|YP_002996545.1| ABC transporter ATP-binding/permease
936154001913	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
936154001914	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
936154001915	Walker A/P-loop; other site
936154001916	ATP binding site [chemical binding]; other site
936154001917	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
936154001918	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
936154001919	Q-loop/lid; other site
936154001920	ABC transporter signature motif; other site
936154001921	Walker B; other site
936154001922	D-loop; other site
936154001923	H-loop/switch region; other site
936154001924	Mevalonate kinase [Lipid metabolism]; Region: ERG12; COG1577
936154001925	diphosphomevalonate decarboxylase; Region: PLN02407
936154001926	diphosphomevalonate decarboxylase; Region: mevDPdecarb; TIGR01240
936154001927	Mevalonate kinase [Lipid metabolism]; Region: ERG12; COG1577
936154001928	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
936154001929	GHMP kinases C terminal; Region: GHMP_kinases_C; pfam08544
936154001930	isopentenyl pyrophosphate isomerase; Provisional; Region: PRK05437
936154001931	Isopentenyl-diphosphate:dimethylallyl diphosphate isomerase type 2 (IDI-2) FMN-binding domain. Two types of IDIs have been characterized at present. The long known IDI-1 is only dependent on divalent metals for activity, whereas IDI-2 requires a metal; Region: IDI-2_FMN; cd02811
936154001932	homotetramer interface [polypeptide binding]; other site
936154001933	FMN binding site [chemical binding]; other site
936154001934	homodimer contacts [polypeptide binding]; other site
936154001935	putative active site [active]
936154001936	putative substrate binding site [chemical binding]; other site
936154001937	Class II hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase (HMGR); Region: HMG-CoA_reductase_classII; cd00644
936154001938	homodimer interface [polypeptide binding]; other site
936154001939	catalytic residues [active]
936154001940	NAD binding site [chemical binding]; other site
936154001941	substrate binding pocket [chemical binding]; other site
936154001942	flexible flap; other site
936154001943	"initiating" condensing enzymes are a subclass of decarboxylating condensing enzymes, including beta-ketoacyl [ACP] synthase, type III and polyketide synthases, type III, which include chalcone synthase and related enzymes. They are...; Region: init_cond_enzymes; cd00827
936154001944	3-hydroxy-3-methylglutaryl CoA synthase, prokaryotic clade; Region: HMG-CoA-S_prok; TIGR01835
936154001945	dimer interface [polypeptide binding]; other site
936154001946	active site
936154001947	thymidylate synthase; Reviewed; Region: thyA; PRK01827
936154001948	Thymidylate synthase and pyrimidine hydroxymethylase: Thymidylate synthase (TS) and deoxycytidylate hydroxymethylase (dCMP-HMase) are homologs that catalyze analogous alkylation of C5 of pyrimidine nucleotides. Both enzymes are involved in the...; Region: TS_Pyrimidine_HMase; cd00351
936154001949	dimerization interface [polypeptide binding]; other site
936154001950	active site
936154001951	Dihydrofolate reductase [Coenzyme metabolism]; Region: FolA; COG0262
936154001952	Dihydrofolate reductase (DHFR). Reduces 7,8-dihydrofolate to 5,6,7,8-tetrahydrofolate with NADPH as a cofactor. This is an essential step in the biosynthesis of deoxythymidine phosphate since 5,6,7,8-tetrahydrofolate is required to regenerate 5; Region: DHFR; cd00209
936154001953	folate binding site [chemical binding]; other site
936154001954	NADP+ binding site [chemical binding]; other site
936154001955	ATP-dependent protease ATP-binding subunit ClpX; Provisional; Region: clpX; PRK05342
936154001956	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
936154001957	Walker A motif; other site
936154001958	ATP binding site [chemical binding]; other site
936154001959	Walker B motif; other site
936154001960	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
936154001961	YihA (EngB) GTPase family; Region: YihA_EngB; cd01876
936154001962	G1 box; other site
936154001963	GTP/Mg2+ binding site [chemical binding]; other site
936154001964	Switch I region; other site
936154001965	G2 box; other site
936154001966	G3 box; other site
936154001967	Switch II region; other site
936154001968	G4 box; other site
936154001969	G5 box; other site
936154001970	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
936154001971	ATPases associated with a variety of cellular activities; Region: AAA; smart00382
936154001972	Walker A motif; other site
936154001973	ATP binding site [chemical binding]; other site
936154001974	ATPases of the AAA+ class [Posttranslational modification, protein turnover, chaperones]; Region: SpoVK; COG0464
936154001975	Walker B motif; other site
936154001976	arginine finger; other site
936154001977	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
936154001978	Walker A motif; other site
936154001979	ATP binding site [chemical binding]; other site
936154001980	Walker B motif; other site
936154001981	arginine finger; other site
936154001982	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431
936154001983	Ribosomal protein L10 family, L10 subfamily; composed of bacterial 50S ribosomal protein and eukaryotic mitochondrial 39S ribosomal protein, L10. L10 occupies the L7/L12 stalk of the ribosome. The N-terminal domain (NTD) of L10 interacts with L11 protein...; Region: Ribosomal_L10; cd05797
936154001984	23S rRNA interface [nucleotide binding]; other site
936154001985	Interface with L7/L12 ribosomal proteins [polypeptide binding]; other site
936154001986	Ribosomal protein L7/L12. Ribosomal protein L7/L12 refers to the large ribosomal subunit proteins L7 and L12, which are identical except that L7 is acetylated at the N terminus. It is a component of the L7/L12 stalk, which is located at the surface of...; Region: Ribosomal_L7_L12; cd00387
936154001987	core dimer interface [polypeptide binding]; other site
936154001988	L10 interface [polypeptide binding]; other site
936154001989	L11 interface [polypeptide binding]; other site
936154001990	putative EF-Tu interaction site [polypeptide binding]; other site
936154001991	putative EF-G interaction site [polypeptide binding]; other site
936154001992	Integrase core domain; Region: rve; pfam00665
936154001993	Integrase core domain; Region: rve_3; cl15866
936154001994	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
936154001995	undecaprenyl phosphate 4-deoxy-4-formamido-L-arabinose transferase; Provisional; Region: PRK10714
936154001996	Bacterial DPM1_like enzymes are related to eukaryotic DPM1; Region: DPM1_like_bac; cd04187
936154001997	DXD motif; other site
936154001998	Putative Catalytic site; other site
936154001999	Predicted membrane protein [Function unknown]; Region: COG2246
936154002000	GtrA-like protein; Region: GtrA; pfam04138
936154002001	Alpha-galactosidases/6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases [Carbohydrate transport and metabolism]; Region: CelF; COG1486
936154002002	Glycoside Hydrolases Family 4; Phospho-beta-glucosidase; Region: GH4_P_beta_glucosidase; cd05296
936154002003	NAD binding site [chemical binding]; other site
936154002004	sugar binding site [chemical binding]; other site
936154002005	divalent metal binding site [ion binding]; other site
936154002006	tetramer (dimer of dimers) interface [polypeptide binding]; other site
936154002007	dimer interface [polypeptide binding]; other site
936154002008	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
936154002009	Transcriptional regulators [Transcription]; Region: RpiR; COG1737
936154002010	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
936154002011	putative active site [active]
936154002012	CoA-disulfide reductase; Region: CoA_CoA_reduc; TIGR03385
936154002013	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
936154002014	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
936154002015	Member of the Rhodanese Homology Domain superfamily. Included in this CD are the Lactococcus lactis NADH oxidase, Bacillus cereus NADH dehydrogenase, and Bacteroides thetaiotaomicron pyridine nucleotide-disulphide oxidoreductase, and similar...; Region: RHOD_Pyr_redox; cd01524
936154002016	active site residue [active]
936154002017	SirA, YedF, and YeeD. Two-layered alpha/beta sandwich domain.  SirA (also known as UvrY,  and YhhP) belongs to a family of bacterial two-component response regulators that controls secondary metabolism and virulence. The other member of this...; Region: SirA_YedF_YeeD; cl00436
936154002018	CPxP  motif; other site
936154002019	DsrE/DsrF/DrsH-like family; Region: DrsE_2; pfam13686
936154002020	Gram-positive signal peptide, YSIRK family; Region: YSIRK_signal; TIGR01168
936154002021	Bacterial SH3 domain; Region: SH3_5; pfam08460
936154002022	Bacterial SH3 domain; Region: SH3_5; pfam08460
936154002023	Bacterial SH3 domain; Region: SH3_5; pfam08460
936154002024	GBS Bsp-like repeat; Region: GBS_Bsp-like; pfam08481
936154002025	Bacterial SH3 domain; Region: SH3_5; pfam08460
936154002026	Predicted xylanase/chitin deacetylase [Carbohydrate transport and metabolism]; Region: CDA1; COG0726
936154002027	NAD(P)+-dependent aldehyde dehydrogenase superfamily; Region: ALDH-SF; cl11961
936154002028	Putative catalytic NodB homology domain of PgaB, IcaB, and similar proteins which consist of a deformed (beta/alpha)8 barrel fold with 5- or 6-strands; Region: CE4_NodB_like_5s_6s; cd10918
936154002029	putative active site [active]
936154002030	putative metal binding site [ion binding]; other site
936154002031	homoserine dehydrogenase; Provisional; Region: PRK06349
936154002032	Homoserine dehydrogenase, NAD binding domain; Region: NAD_binding_3; pfam03447
936154002033	Homoserine dehydrogenase; Region: Homoserine_dh; pfam00742
936154002034	ACT_HSDH_Hom CD includes the C-terminal ACT domain of the NAD(P)H-dependent, homoserine dehydrogenase (HSDH) and related domains; Region: ACT_HSDH-Hom; cd04881
936154002035	homoserine kinase; Provisional; Region: PRK01212
936154002036	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
936154002037	GHMP kinases C terminal; Region: GHMP_kinases_C; pfam08544
936154002038	folylpolyglutamate synthase/dihydrofolate synthase; Region: folC; TIGR01499
936154002039	Bacteriophage translational regulator; Region: Translat_reg; cl17773
936154002040	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
936154002041	GTP cyclohydrolase I (GTP-CH-I) catalyzes the conversion of GTP into dihydroneopterin triphosphate.  The enzyme product is the precursor of tetrahydrofolate in eubacteria, fungi, and plants and of the folate analogs in methanogenic bacteria.  In...; Region: GTP_cyclohydro1; cd00642
936154002042	homodecamer interface [polypeptide binding]; other site
936154002043	GTP cyclohydrolase I; Provisional; Region: PLN03044
936154002044	active site
936154002045	putative catalytic site residues [active]
936154002046	zinc binding site [ion binding]; other site
936154002047	GTP-CH-I/GFRP interaction surface; other site
936154002048	DHPS subgroup of Pterin binding enzymes. DHPS (dihydropteroate synthase), a functional homodimer, catalyzes the condensation of p-aminobenzoic acid (pABA) in the de novo biosynthesis of folate, which is an essential cofactor in both nucleic acid and...; Region: DHPS; cd00739
936154002049	dihydropteroate synthase; Region: DHPS; TIGR01496
936154002050	substrate binding pocket [chemical binding]; other site
936154002051	dimer interface [polypeptide binding]; other site
936154002052	inhibitor binding site; inhibition site
936154002053	Dihydroneopterin aldolase (DHNA) and 7,8-dihydroneopterin triphosphate epimerase domain (DHNTPE); these enzymes have been designated folB and folX, respectively. Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and...; Region: DHNA_DHNTPE; cd00534
936154002054	homooctamer interface [polypeptide binding]; other site
936154002055	active site
936154002056	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK). Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and amino acids as well as formyl-tRNA. Mammalian cells are able to utilize pre-formed folates after...; Region: HPPK; cd00483
936154002057	catalytic center binding site [active]
936154002058	ATP binding site [chemical binding]; other site
936154002059	UDP-N-acetylenolpyruvoylglucosamine reductase; Provisional; Region: murB; PRK13905
936154002060	FAD binding domain; Region: FAD_binding_4; pfam01565
936154002061	UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain; Region: MurB_C; pfam02873
936154002062	ABC-type spermidine/putrescine transport systems, ATPase components [Amino acid transport and metabolism]; Region: PotA; COG3842
936154002063	ATP-binding cassette domain of the polyamine transporter; Region: ABC_PotA_N; cd03300
936154002064	Walker A/P-loop; other site
936154002065	ATP binding site [chemical binding]; other site
936154002066	Q-loop/lid; other site
936154002067	ABC transporter signature motif; other site
936154002068	Walker B; other site
936154002069	D-loop; other site
936154002070	H-loop/switch region; other site
936154002071	TOBE domain; Region: TOBE_2; pfam08402
936154002072	sulfate transport protein; Provisional; Region: cysT; CHL00187
936154002073	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
936154002074	dimer interface [polypeptide binding]; other site
936154002075	conserved gate region; other site
936154002076	putative PBP binding loops; other site
936154002077	ABC-ATPase subunit interface; other site
936154002078	ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177
936154002079	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
936154002080	dimer interface [polypeptide binding]; other site
936154002081	conserved gate region; other site
936154002082	putative PBP binding loops; other site
936154002083	ABC-ATPase subunit interface; other site
936154002084	Spermidine/putrescine-binding periplasmic protein [Amino acid transport and metabolism]; Region: PotD; COG0687
936154002085	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; cl17199
936154002086	Response regulator of citrate/malate metabolism [Transcription / Signal transduction mechanisms]; Region: CitB; COG4565
936154002087	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
936154002088	active site
936154002089	phosphorylation site [posttranslational modification]
936154002090	intermolecular recognition site; other site
936154002091	dimerization interface [polypeptide binding]; other site
936154002092	Signal transduction histidine kinase regulating citrate/malate metabolism [Signal transduction mechanisms]; Region: CitA; COG3290
936154002093	Signal transduction histidine kinase regulating citrate/malate metabolism [Signal transduction mechanisms]; Region: CitA; COG3290
936154002094	2-hydroxycarboxylate transporter family; Region: 2HCT; cl01386
936154002095	Malic enzyme [Energy production and conversion]; Region: SfcA; COG0281
936154002096	Malic enzyme, N-terminal domain; Region: malic; pfam00390
936154002097	NAD(P) binding domain of malic enzyme (ME), subgroup 2; Region: NAD_bind_2_malic_enz; cd05311
936154002098	putative NAD(P) binding site [chemical binding]; other site
936154002099	ClC chloride channel EriC.  This domain is found in the EriC chloride transporters that mediate the extreme acid resistance response in eubacteria and archaea. This response allows bacteria to survive in the acidic environments by decarboxylation-linked...; Region: EriC; cd01031
936154002100	Chloride channel protein EriC [Inorganic ion transport and metabolism]; Region: EriC; COG0038
936154002101	Cl- selectivity filter; other site
936154002102	Cl- binding residues [ion binding]; other site
936154002103	pore gating glutamate residue; other site
936154002104	dimer interface [polypeptide binding]; other site
936154002105	H+/Cl- coupling transport residue; other site
936154002106	TrkA-C domain; Region: TrkA_C; pfam02080
936154002107	transcriptional antiterminator BglG; Provisional; Region: PRK09772
936154002108	CAT RNA binding domain; Region: CAT_RBD; smart01061
936154002109	PRD domain; Region: PRD; pfam00874
936154002110	PRD domain; Region: PRD; pfam00874
936154002111	PTS system, beta-glucoside-specific IIABC component; Region: PTS-II-ABC-beta; TIGR01995
936154002112	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
936154002113	active site turn [active]
936154002114	phosphorylation site [posttranslational modification]
936154002115	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
936154002116	PTS_IIA, PTS system, glucose/sucrose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_glc; cd00210
936154002117	HPr interaction site; other site
936154002118	glycerol kinase (GK) interaction site [polypeptide binding]; other site
936154002119	active site
936154002120	phosphorylation site [posttranslational modification]
936154002121	Esterases and lipases (includes fungal lipases, cholinesterases, etc.)  These enzymes act on carboxylic esters (EC: 3.1.1.-). The catalytic apparatus involves three residues (catalytic triad): a serine, a glutamate or aspartate and a histidine.These...; Region: Esterase_lipase; cd00312
936154002122	Carboxylesterase type B [Lipid metabolism]; Region: PnbA; COG2272
936154002123	substrate binding pocket [chemical binding]; other site
936154002124	catalytic triad [active]
936154002125	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
936154002126	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
936154002127	Glycosyl hydrolase family 1; Region: Glyco_hydro_1; cl01046
936154002128	beta-galactosidase; Region: BGL; TIGR03356
936154002129	SGNH_hydrolase, or GDSL_hydrolase, is a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely...; Region: SGNH_hydrolase; cl01053
936154002130	active site
936154002131	catalytic triad [active]
936154002132	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
936154002133	haloacid dehalogenase-like hydrolase; Region: Hydrolase_3; pfam08282
936154002134	active site
936154002135	motif I; other site
936154002136	motif II; other site
936154002137	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cl17915
936154002138	Glycosyl hydrolase family 1; Region: Glyco_hydro_1; cl01046
936154002139	beta-galactosidase; Region: BGL; TIGR03356
936154002140	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
936154002141	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
936154002142	catalytic core [active]
936154002143	Membrane transport protein; Region: Mem_trans; cl09117
936154002144	6-phospho-beta-glucosidase; Reviewed; Region: arb; PRK09593
936154002145	beta-galactosidase; Region: BGL; TIGR03356
936154002146	Domain of unknown function DUF20; Region: UPF0118; pfam01594
936154002147	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; COG0628
936154002148	hypothetical protein; Reviewed; Region: PRK00024
936154002149	Type 1 glutamine amidotransferase (GATase1)-like domain; Region: GAT_1; cl00020
936154002150	conserved cys residue [active]
936154002151	AT-rich DNA-binding protein [General function prediction only]; Region: COG2344
936154002152	Putative DNA-binding protein N-terminus; Region: Put_DNA-bind_N; pfam06971
936154002153	CoA binding domain; Region: CoA_binding; pfam02629
936154002154	Putative amino acid metabolism; Region: DUF1831; pfam08866
936154002155	cysteine desulfurase NifS; Region: FeS_nifS; TIGR03402
936154002156	Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes [Amino acid transport and metabolism]; Region: NifS; COG1104
936154002157	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
936154002158	catalytic residue [active]
936154002159	ribose-phosphate pyrophosphokinase; Provisional; Region: PRK02458
936154002160	N-terminal domain of ribose phosphate pyrophosphokinase; Region: Pribosyltran_N; pfam13793
936154002161	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
936154002162	active site
936154002163	Uncharacterized subgroup 1 of the CYTH-like superfamily; Region: CYTH-like_Pase_1; cd07762
936154002164	putative active site [active]
936154002165	putative metal binding residues [ion binding]; other site
936154002166	signature motif; other site
936154002167	putative triphosphate binding site [ion binding]; other site
936154002168	Nucleotidyltransferase (NT) domain of RelA- and SpoT-like ppGpp synthetases and hydrolases; Region: NT_Rel-Spo_like; cd05399
936154002169	synthetase active site [active]
936154002170	NTP binding site [chemical binding]; other site
936154002171	metal binding site [ion binding]; metal-binding site
936154002172	inorganic polyphosphate/ATP-NAD kinase; Provisional; Region: ppnK; PRK04885
936154002173	ATP-NAD kinase; Region: NAD_kinase; pfam01513
936154002174	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
936154002175	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
936154002176	active site
936154002177	phosphotransacetylase; Reviewed; Region: eutD; PRK09653
936154002178	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
936154002179	Major Facilitator Superfamily; Region: MFS_1; pfam07690
936154002180	putative substrate translocation pore; other site
936154002181	Uncharacterized conserved protein [Function unknown]; Region: COG2461
936154002182	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
936154002183	haloacid dehalogenase-like hydrolase; Region: Hydrolase_3; pfam08282
936154002184	active site
936154002185	motif I; other site
936154002186	motif II; other site
936154002187	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
936154002188	NADPH:quinone reductase and related Zn-dependent oxidoreductases [Energy production and conversion / General function prediction only]; Region: Qor; COG0604
936154002189	Quinone oxidoreductase (QOR); Region: quinone_oxidoreductase_like_1; cd08243
936154002190	putative NAD(P) binding site [chemical binding]; other site
936154002191	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
936154002192	MarR family; Region: MarR_2; pfam12802
936154002193	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
936154002194	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
936154002195	Walker A/P-loop; other site
936154002196	ATP binding site [chemical binding]; other site
936154002197	Q-loop/lid; other site
936154002198	ABC transporter signature motif; other site
936154002199	Walker B; other site
936154002200	D-loop; other site
936154002201	H-loop/switch region; other site
936154002202	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
936154002203	dimer interface [polypeptide binding]; other site
936154002204	conserved gate region; other site
936154002205	ABC-ATPase subunit interface; other site
936154002206	Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein) [Cell envelope biogenesis, outer membrane]; Region: OpuBC; COG1732
936154002207	ABC-type proline/glycine betaine transport systems, periplasmic components [Amino acid transport and metabolism]; Region: ProX; cl17891
936154002208	Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase [Carbohydrate transport and metabolism]; Region: BglB; COG2723
936154002209	beta-galactosidase; Region: BGL; TIGR03356
936154002210	guanosine 5'-monophosphate oxidoreductase; Provisional; Region: PRK05458
936154002211	IMPDH: The catalytic domain of the inosine monophosphate dehydrogenase. IMPDH catalyzes the NAD-dependent oxidation of inosine 5'-monophosphate (IMP) to xanthosine 5' monophosphate (XMP). It is a rate-limiting step in the de novo synthesis of...; Region: IMPDH; cd00381
936154002212	active site
936154002213	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
936154002214	active site
936154002215	xanthine permease; Region: pbuX; TIGR03173
936154002216	Sulfate transporter family; Region: Sulfate_transp; pfam00916
936154002217	Membrane-associated lipoprotein involved in thiamine biosynthesis [Coenzyme metabolism]; Region: ApbE; COG1477
936154002218	ApbE family; Region: ApbE; pfam02424
936154002219	4-oxalocrotonate tautomerase; Provisional; Region: PRK02289
936154002220	active site 1 [active]
936154002221	dimer interface [polypeptide binding]; other site
936154002222	hexamer interface [polypeptide binding]; other site
936154002223	active site 2 [active]
936154002224	thymidine kinase; Provisional; Region: PRK04296
936154002225	peptide chain release factor 1; Validated; Region: prfA; PRK00591
936154002226	This domain is found in peptide chain release factors; Region: PCRF; smart00937
936154002227	RF-1 domain; Region: RF-1; pfam00472
936154002228	potential frameshift: common BLAST hit: gi|222153024|ref|YP_002562201.1| methyltransferase
936154002229	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
936154002230	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
936154002231	Putative translation factor (SUA5) [Translation, ribosomal structure and biogenesis]; Region: SUA5; COG0009
936154002232	Acetyltransferase (GNAT) domain; Region: Acetyltransf_4; pfam13420
936154002233	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
936154002234	Coenzyme A binding pocket [chemical binding]; other site
936154002235	serine hydroxymethyltransferase; Reviewed; Region: glyA; PRK00011
936154002236	Serine-glycine hydroxymethyltransferase (SHMT). This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). SHMT carries out interconversion of serine and glycine; it catalyzes the transfer of hydroxymethyl...; Region: SHMT; cd00378
936154002237	dimer interface [polypeptide binding]; other site
936154002238	active site
936154002239	glycine-pyridoxal phosphate binding site [chemical binding]; other site
936154002240	folate binding site [chemical binding]; other site
936154002241	37-kD nucleoid-associated bacterial protein; Region: NA37; pfam04245
936154002242	Lysozyme-like; Region: Lysozyme_like; pfam13702
936154002243	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) [Cell envelope biogenesis, outer membrane]; Region: MltE; COG0741
936154002244	catalytic residue [active]
936154002245	coenzyme A disulfide reductase; Reviewed; Region: PRK09564
936154002246	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
936154002247	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
936154002248	Pyrimidine reductase, riboflavin biosynthesis [Coenzyme metabolism]; Region: RibD; COG1985
936154002249	RibD C-terminal domain; Region: RibD_C; cl17279
936154002250	L-lactate dehydrogenase; Reviewed; Region: ldh; PRK00066
936154002251	L-2-hydroxyisocapronate dehydrogenases and some bacterial L-lactate dehydrogenases; Region: HicDH_like; cd05291
936154002252	tetramer (dimer of dimers) interface [polypeptide binding]; other site
936154002253	NAD binding site [chemical binding]; other site
936154002254	dimer interface [polypeptide binding]; other site
936154002255	substrate binding site [chemical binding]; other site
936154002256	DNA gyrase subunit A; Validated; Region: PRK05560
936154002257	DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes...; Region: TOP4c; cd00187
936154002258	CAP-like domain; other site
936154002259	active site
936154002260	primary dimer interface [polypeptide binding]; other site
936154002261	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
936154002262	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
936154002263	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
936154002264	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
936154002265	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
936154002266	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
936154002267	Sortase A (SrtA) or subfamily-1 sortases are cysteine transpeptidases found in gram-positive bacteria that anchor surface proteins to peptidoglycans of the bacterial cell wall envelope. They do so by catalyzing a transpeptidation reaction in which the...; Region: Sortase_A_1; cd06165
936154002268	active site
936154002269	catalytic site [active]
936154002270	This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_1; cd08352
936154002271	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
936154002272	putative metal binding site [ion binding]; other site
936154002273	Predicted secreted protein [Function unknown]; Region: COG4086
936154002274	Protein of unknown function (DUF1002); Region: DUF1002; pfam06207
936154002275	ABC-type metal ion transport system, periplasmic component/surface adhesin [Inorganic ion transport and metabolism]; Region: LraI; COG0803
936154002276	Helical backbone metal receptor (TroA-like domain). These proteins have been shown to function in the ABC transport of ferric siderophores and metal ions such as Mn2+, Fe3+, Cu2+ and/or Zn2+.  Their ligand binding site is formed in the interface between...; Region: TroA-like; cl00262
936154002277	intersubunit interface [polypeptide binding]; other site
936154002278	streptococcal histidine triad protein; Region: strep_his_triad; TIGR01363
936154002279	Streptococcal histidine triad protein; Region: Strep_his_triad; pfam04270
936154002280	Streptococcal histidine triad protein; Region: Strep_his_triad; pfam04270
936154002281	Streptococcal histidine triad protein; Region: Strep_his_triad; pfam04270
936154002282	Protein of unknown function (DUF554); Region: DUF554; pfam04474
936154002283	Glutathione (GSH) peroxidase family; tetrameric selenoenzymes that catalyze the reduction of a variety of hydroperoxides including lipid peroxidases, using GSH as a specific electron donor substrate. GSH peroxidase contains one selenocysteine residue per...; Region: GSH_Peroxidase; cd00340
936154002284	catalytic residues [active]
936154002285	dimer interface [polypeptide binding]; other site
936154002286	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
936154002287	non-specific DNA binding site [nucleotide binding]; other site
936154002288	salt bridge; other site
936154002289	sequence-specific DNA binding site [nucleotide binding]; other site
936154002290	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
936154002291	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
936154002292	DNA-binding site [nucleotide binding]; DNA binding site
936154002293	The UbiC transcription regulator-associated (UTRA) domain is a conserved ligand-binding domain; Region: UTRA; smart00866
936154002294	ADP-ribosylglycohydrolase; Region: ADP_ribosyl_GH; pfam03747
936154002295	Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase [Carbohydrate transport and metabolism]; Region: BglB; COG2723
936154002296	beta-galactosidase; Region: BGL; TIGR03356
936154002297	Phosphotransferase system cellobiose-specific component IIC [Carbohydrate transport and metabolism]; Region: CelB; COG1455
936154002298	Phosphotransferase system, EIIC; Region: PTS_EIIC; pfam02378
936154002299	PTS_IIB: subunit IIB of enzyme II (EII) is the central energy-coupling domain of the phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In the multienzyme PTS complex, EII is a carbohydrate-specific permease consisting of two cytoplasmic...; Region: PTS_IIB; cl10014
936154002300	active site
936154002301	P-loop; other site
936154002302	phosphorylation site [posttranslational modification]
936154002303	Transposase IS200 like; Region: Y1_Tnp; cl00848
936154002304	Transposase IS200 like; Region: Y1_Tnp; pfam01797
936154002305	Dipeptide/tripeptide permease [Amino acid transport and metabolism]; Region: PTR2; COG3104
936154002306	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
936154002307	putative substrate translocation pore; other site
936154002308	POT family; Region: PTR2; cl17359
936154002309	Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: KefB; COG0475
936154002310	Sodium/hydrogen exchanger family; Region: Na_H_Exchanger; pfam00999
936154002311	GMP synthase; Reviewed; Region: guaA; PRK00074
936154002312	Type 1 glutamine amidotransferase (GATase1) domain found in GMP synthetase; Region: GATase1_GMP_Synthase; cd01742
936154002313	AMP/PPi binding site [chemical binding]; other site
936154002314	candidate oxyanion hole; other site
936154002315	catalytic triad [active]
936154002316	potential glutamine specificity residues [chemical binding]; other site
936154002317	The C-terminal domain of GMP synthetase. It contains two subdomains; the ATP pyrophosphatase domain which closes to the N-termial and the dimerization domain at C-terminal end. The ATP-PPase is a twisted, five-stranded parallel beta-sheet sandwiched...; Region: GMP_synthase_C; cd01997
936154002318	ATP Binding subdomain [chemical binding]; other site
936154002319	Dimerization subdomain; other site
936154002320	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
936154002321	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
936154002322	DNA-binding site [nucleotide binding]; DNA binding site
936154002323	UTRA domain; Region: UTRA; pfam07702
936154002324	Putative helix-turn-helix protein, YlxM / p13 like; Region: UPF0122; pfam04297
936154002325	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed...; Region: HTH_Hin_like; cd00569
936154002326	signal recognition particle protein; Provisional; Region: PRK10867
936154002327	SRP54-type protein, helical bundle domain; Region: SRP54_N; smart00963
936154002328	The signal recognition particle (SRP) mediates the transport to or across the plasma membrane in bacteria and the endoplasmic reticulum in eukaryotes. SRP recognizes N-terminal sighnal sequences of newly synthesized polypeptides at the ribosome. The...; Region: SRP; cd03115
936154002329	P loop; other site
936154002330	GTP binding site [chemical binding]; other site
936154002331	Signal peptide binding domain; Region: SRP_SPB; pfam02978
936154002332	YolD-like protein; Region: YolD; pfam08863
936154002333	umuC subunit of DNA Polymerase V; Region: PolY_Pol_V_umuC; cd01700
936154002334	active site
936154002335	DNA binding site [nucleotide binding]
936154002336	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
936154002337	SOS-response transcriptional repressors (RecA-mediated autopeptidases) [Transcription / Signal transduction mechanisms]; Region: LexA; COG1974
936154002338	non-specific DNA binding site [nucleotide binding]; other site
936154002339	salt bridge; other site
936154002340	sequence-specific DNA binding site [nucleotide binding]; other site
936154002341	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
936154002342	Catalytic site [active]
936154002343	putative oxidoreductase; Provisional; Region: PRK10206
936154002344	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
936154002345	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
936154002346	Domain of unknown function (DU1801); Region: DUF1801; pfam08818
936154002347	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
936154002348	haloacid dehalogenase-like hydrolase; Region: Hydrolase_3; pfam08282
936154002349	active site
936154002350	motif I; other site
936154002351	motif II; other site
936154002352	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
936154002353	Pyridoxamine 5'-phosphate oxidase; Region: Pyridox_oxidase; pfam01243
936154002354	Transcriptional regulators [Transcription]; Region: RpiR; COG1737
936154002355	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
936154002356	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
936154002357	putative active site [active]
936154002358	potential frameshift: common BLAST hit: gi|288904620|ref|YP_003429841.1| PTS system, beta-glucoside specific, IIABC components
936154002359	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
936154002360	active site turn [active]
936154002361	phosphorylation site [posttranslational modification]
936154002362	PTS system, glucose-like IIB component; Region: EIIB_glc; TIGR00826
936154002363	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
936154002364	potential frameshift: common BLAST hit: gi|325977596|ref|YP_004287312.1| PTS system beta-glucosides-specific transporter subunit IIA
936154002365	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
936154002366	Phosphotransferase system IIA components [Carbohydrate transport and metabolism]; Region: NagE; COG2190
936154002367	HPr interaction site; other site
936154002368	glycerol kinase (GK) interaction site [polypeptide binding]; other site
936154002369	active site
936154002370	phosphorylation site [posttranslational modification]
936154002371	Glycosyl hydrolase family 1; Region: Glyco_hydro_1; cl01046
936154002372	beta-galactosidase; Region: BGL; TIGR03356
936154002373	alcohol dehydrogenase and quinone reductase-like medium chain degydrogenases/reductases; Region: MDR_like_2; cd05289
936154002374	NADPH:quinone reductase and related Zn-dependent oxidoreductases [Energy production and conversion / General function prediction only]; Region: Qor; COG0604
936154002375	putative NAD(P) binding site [chemical binding]; other site
936154002376	Mannose-6-phosphate isomerase [Carbohydrate transport and metabolism]; Region: {ManC}; COG0662
936154002377	Predicted flavoprotein [General function prediction only]; Region: COG0431
936154002378	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
936154002379	Predicted flavoprotein [General function prediction only]; Region: COG0431
936154002380	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
936154002381	FMN-binding domain; Region: FMN_bind; pfam04205
936154002382	flavocytochrome c; Region: flavo_cyto_c; TIGR01813
936154002383	L-aspartate oxidase; Provisional; Region: PRK06175
936154002384	Metal-dependent amidase/aminoacylase/carboxypeptidase [General function prediction only]; Region: AbgB; COG1473
936154002385	M20 Peptidase Aminoacylase 1 subfamily; Region: M20_Acy1_like6; cd05664
936154002386	metal binding site [ion binding]; metal-binding site
936154002387	putative dimer interface [polypeptide binding]; other site
936154002388	Uncharacterized conserved protein [Function unknown]; Region: COG2966
936154002389	Protein of unknown function (DUF1212); Region: DUF1212; pfam06738
936154002390	FemAB family; Region: FemAB; pfam02388
936154002391	Acetyltransferase (GNAT) domain; Region: Acetyltransf_6; cl17497
936154002392	Uncharacterized protein/domain associated with GTPases [Function unknown]; Region: COG3597
936154002393	site-specific tyrosine recombinase XerS; Reviewed; Region: xerS; PRK05084
936154002394	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
936154002395	active site
936154002396	DNA binding site [nucleotide binding]
936154002397	Int/Topo IB signature motif; other site
936154002398	NADH:flavin oxidoreductases, Old Yellow Enzyme family [Energy production and conversion]; Region: NemA; COG1902
936154002399	TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl17186
936154002400	phosphate binding site [ion binding]; other site
936154002401	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) MazG-like domain found in integron-associated MazG (iMazG) proteins; Region: NTP-PPase_iMazG; cd11536
936154002402	homodimer interface [polypeptide binding]; other site
936154002403	putative chemical substrate binding site [chemical binding]; other site
936154002404	oligomer interface [polypeptide binding]; other site
936154002405	metal binding site [ion binding]; metal-binding site
936154002406	ornithine cyclodeaminase; Validated; Region: PRK08618
936154002407	ornithine cyclodeaminase; Validated; Region: PRK06823; cl17400
936154002408	Sulfite exporter TauE/SafE; Region: TauE; pfam01925
936154002409	Predicted transcriptional regulators [Transcription]; Region: COG1378
936154002410	Sugar-specific transcriptional regulator TrmB; Region: TrmB; pfam01978
936154002411	Middle phospholipase D-like domain of the transcriptional regulator TrmB and similar proteins; Region: PLDc_like_TrmB_middle; cd09124
936154002412	C-terminal domain interface [polypeptide binding]; other site
936154002413	sugar binding site [chemical binding]; other site
936154002414	Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly...; Region: Nudix_Hydrolase_34; cd04693
936154002415	nudix motif; other site
936154002416	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
936154002417	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
936154002418	ATP binding site [chemical binding]; other site
936154002419	Mg2+ binding site [ion binding]; other site
936154002420	G-X-G motif; other site
936154002421	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
936154002422	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
936154002423	active site
936154002424	phosphorylation site [posttranslational modification]
936154002425	intermolecular recognition site; other site
936154002426	dimerization interface [polypeptide binding]; other site
936154002427	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
936154002428	DNA binding site [nucleotide binding]
936154002429	potential frameshift: common BLAST hit: gi|225868548|ref|YP_002744496.1| transporter permease
936154002430	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
936154002431	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
936154002432	Walker A/P-loop; other site
936154002433	ATP binding site [chemical binding]; other site
936154002434	Q-loop/lid; other site
936154002435	ABC transporter signature motif; other site
936154002436	Walker B; other site
936154002437	D-loop; other site
936154002438	H-loop/switch region; other site
936154002439	PASTA domain of bacterial serine/threonine kinase pknB-like proteins. PknB is a member of a group of related transmembrane sensor kinases present in many gram positive bacteria, which has been shown to regulate cell shape in Mycobacterium tubercolosis; Region: PASTA_pknB; cd06577
936154002440	tRNA (uracil-5-)-methyltransferase Gid; Reviewed; Region: PRK05335
936154002441	Glucose inhibited division protein A; Region: GIDA; pfam01134
936154002442	Protein of unknown function (DUF3307); Region: DUF3307; pfam11750
936154002443	D-lactate dehydrogenase; Validated; Region: PRK08605
936154002444	D-Lactate dehydrogenase and D-2-Hydroxyisocaproic acid dehydrogenase (D-HicDH), NAD-binding and catalytic domains; Region: LDH; cd12186
936154002445	homodimer interface [polypeptide binding]; other site
936154002446	ligand binding site [chemical binding]; other site
936154002447	NAD binding site [chemical binding]; other site
936154002448	catalytic site [active]
936154002449	Predicted membrane protein, putative toxin regulator [General function prediction only]; Region: PfoR; COG3641
936154002450	Phosphotransferase system, EIIC; Region: PTS_EIIC_2; pfam13303
936154002451	Transcriptional regulator [Transcription]; Region: LysR; COG0583
936154002452	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
936154002453	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
936154002454	dimerization interface [polypeptide binding]; other site
936154002455	DNA topoisomerase I; Validated; Region: PRK05582
936154002456	TOPRIM_TopoIA_TopoI: The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to Escherichia coli DNA topoisomerase I.   Type IA DNA topoisomerases remove (relax) negative supercoils in the...; Region: TOPRIM_TopoIA_TopoI; cd03363
936154002457	active site
936154002458	interdomain interaction site; other site
936154002459	putative metal-binding site [ion binding]; other site
936154002460	nucleotide binding site [chemical binding]; other site
936154002461	DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cd00186
936154002462	domain I; other site
936154002463	DNA binding groove [nucleotide binding]
936154002464	phosphate binding site [ion binding]; other site
936154002465	domain II; other site
936154002466	domain III; other site
936154002467	nucleotide binding site [chemical binding]; other site
936154002468	catalytic site [active]
936154002469	domain IV; other site
936154002470	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
936154002471	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
936154002472	DNA protecting protein DprA; Region: dprA; TIGR00732
936154002473	DNA recombination-mediator protein A; Region: DNA_processg_A; pfam02481
936154002474	maltose O-acetyltransferase; Provisional; Region: PRK10092
936154002475	Maltose O-acetyltransferase (MAT) and Galactoside O-acetyltransferase (GAT): MAT and GAT catalyze the CoA-dependent acetylation of the 6-hydroxyl group of their respective sugar substrates. MAT acetylates maltose and glucose exclusively at the C6...; Region: LbH_MAT_GAT; cd03357
936154002476	active site
936154002477	substrate binding site [chemical binding]; other site
936154002478	trimer interface [polypeptide binding]; other site
936154002479	CoA binding site [chemical binding]; other site
936154002480	bacterial Ribonuclease HII-like; Region: RNase_HII_bacteria_HII_like; cd07182
936154002481	RNA/DNA hybrid binding site [nucleotide binding]; other site
936154002482	active site
936154002483	GTPase YlqF; Reviewed; Region: rbgA; PRK09563
936154002484	Circularly permuted YlqF GTPase; Region: YlqF; cd01856
936154002485	GTP/Mg2+ binding site [chemical binding]; other site
936154002486	G4 box; other site
936154002487	G5 box; other site
936154002488	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cl17170
936154002489	G1 box; other site
936154002490	G1 box; other site
936154002491	GTP/Mg2+ binding site [chemical binding]; other site
936154002492	Switch I region; other site
936154002493	G2 box; other site
936154002494	G2 box; other site
936154002495	Switch I region; other site
936154002496	G3 box; other site
936154002497	G3 box; other site
936154002498	Switch II region; other site
936154002499	Switch II region; other site
936154002500	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
936154002501	MarR family; Region: MarR_2; pfam12802
936154002502	lipoyltransferase and lipoate-protein ligase; Region: lipoyltrans; TIGR00545
936154002503	Lipoate-protein ligase A [Coenzyme metabolism]; Region: LplA; COG0095
936154002504	Bacterial lipoate protein ligase C-terminus; Region: Lip_prot_lig_C; pfam10437
936154002505	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes [Energy production and conversion]; Region: Lpd; COG1249
936154002506	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
936154002507	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
936154002508	OsmC-like protein; Region: OsmC; pfam02566
936154002509	Domain of unknown function (DUF1836); Region: DUF1836; pfam08876
936154002510	Predicted membrane protein, hemolysin III homolog [General function prediction only]; Region: COG1272
936154002511	channel protein, hemolysin III family; Region: hlyIII; TIGR01065
936154002512	Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase [Lipid metabolism / General function prediction only]; Region: LCB5; COG1597
936154002513	ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only]; Region: Uup; COG0488
936154002514	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
936154002515	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
936154002516	ABC transporter; Region: ABC_tran_2; pfam12848
936154002517	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
936154002518	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism]; Region: ARO8; COG1167
936154002519	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
936154002520	DNA-binding site [nucleotide binding]; DNA binding site
936154002521	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
936154002522	pyridoxal 5'-phosphate binding site [chemical binding]; other site
936154002523	homodimer interface [polypeptide binding]; other site
936154002524	ATP cone domain; Region: ATP-cone; pfam03477
936154002525	Dihydrodipicolinate synthase/N-acetylneuraminate lyase [Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: DapA; COG0329
936154002526	Dihydrodipicolinate synthase (DHDPS); Region: DHDPS; cd00950
936154002527	dimer interface [polypeptide binding]; other site
936154002528	active site
936154002529	catalytic residue [active]
936154002530	aspartate-semialdehyde dehydrogenase; Provisional; Region: PRK14874
936154002531	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
936154002532	Phosphatidylserine/phosphatidylglycerophosphate/car diolipin synthases and related enzymes [Lipid metabolism]; Region: Cls; COG1502
936154002533	Putative catalytic domain, repeat 1, of Streptococcus mutans uncharacterized protein SMU_988 and similar proteins; Region: PLDc_SMU_988_like_1; cd09154
936154002534	putative active site [active]
936154002535	catalytic site [active]
936154002536	Putative catalytic domain, repeat 2, of Streptococcus mutans uncharacterized protein SMU_988 and similar proteins; Region: PLDc_SMU_988_like_2; cd09160
936154002537	putative active site [active]
936154002538	catalytic site [active]
936154002539	Domain of unknown function (DUF1905); Region: DUF1905; pfam08922
936154002540	formate--tetrahydrofolate ligase; Provisional; Region: PRK13505
936154002541	Formyltetrahydrofolate synthetase (FTHFS) catalyzes the ATP-dependent activation of formate ion via its addition to the N10 position of tetrahydrofolate. FTHFS is a highly expressed key enzyme in both the Wood-Ljungdahl pathway of autotrophic CO2...; Region: FTHFS; cd00477
936154002542	Potassium binding sites [ion binding]; other site
936154002543	Cesium cation binding sites [ion binding]; other site
936154002544	phosphopantothenate--cysteine ligase; Validated; Region: PRK06732
936154002545	Flavoprotein; Region: Flavoprotein; pfam02441
936154002546	Predicted membrane protein [Function unknown]; Region: COG4684
936154002547	phosphoglucomutase-2-like protein; Provisional; Region: PTZ00150
936154002548	This CD includes PGM2 (phosphoglucomutase 2) and PGM2L1 (phosphoglucomutase 2-like 1). The mammalian PGM2 is thought to be a phosphopentomutase that catalyzes the conversion of the nucleoside breakdown products, ribose-1-phosphate and...; Region: PGM2; cd05799
936154002549	active site
936154002550	substrate binding site [chemical binding]; other site
936154002551	metal binding site [ion binding]; metal-binding site
936154002552	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
936154002553	Transmembrane subunit (TM) of Treponema pallidum (Tp) RbsC-1, RbsC-2 and related proteins. This is a functionally uncharacterized subgroup of TMs which belong to a larger group of TMs of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette; Region: TM_PBP1_transp_TpRbsC_like; cd06580
936154002554	TM-ABC transporter signature motif; other site
936154002555	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
936154002556	Transmembrane subunit (TM) of Treponema pallidum (Tp) RbsC-1, RbsC-2 and related proteins. This is a functionally uncharacterized subgroup of TMs which belong to a larger group of TMs of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette; Region: TM_PBP1_transp_TpRbsC_like; cd06580
936154002557	TM-ABC transporter signature motif; other site
936154002558	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
936154002559	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
936154002560	Walker A/P-loop; other site
936154002561	ATP binding site [chemical binding]; other site
936154002562	Q-loop/lid; other site
936154002563	ABC transporter signature motif; other site
936154002564	Walker B; other site
936154002565	D-loop; other site
936154002566	H-loop/switch region; other site
936154002567	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
936154002568	Walker A/P-loop; other site
936154002569	ATP binding site [chemical binding]; other site
936154002570	Uncharacterized ABC-type transport system, periplasmic component/surface lipoprotein [General function prediction only]; Region: Med; COG1744
936154002571	Periplasmic binding domain of basic membrane lipoprotein, PnrA, in Treponema pallidum and its homologs from other bacteria and Archaea; Region: PBP1_BmpA_PnrA_like; cd06354
936154002572	ligand binding site [chemical binding]; other site
936154002573	Cytidine deaminase zinc-binding domain. These enzymes are Zn dependent. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a water molecule to form a hydroxide ion that performs a nucleophilic attack on...; Region: cytidine_deaminase; cd01283
936154002574	active site
936154002575	catalytic motif [active]
936154002576	Zn binding site [ion binding]; other site
936154002577	2-deoxyribose-5-phosphate aldolase (DERA) of the DeoC family; Region: DeoC; cd00959
936154002578	intersubunit interface [polypeptide binding]; other site
936154002579	active site
936154002580	catalytic residue [active]
936154002581	pyrimidine-nucleoside phosphorylase; Reviewed; Region: PRK06078
936154002582	Glycosyl transferase family, helical bundle domain; Region: Glycos_trans_3N; pfam02885
936154002583	Glycosyl transferase family, a/b domain; Region: Glycos_transf_3; pfam00591
936154002584	Pyrimidine nucleoside phosphorylase C-terminal domain; Region: PYNP_C; pfam07831
936154002585	16S RNA G1207 methylase RsmC [Translation, ribosomal structure and biogenesis]; Region: RsmC; COG2813
936154002586	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
936154002587	S-adenosylmethionine binding site [chemical binding]; other site
936154002588	pantothenate kinase; Provisional; Region: PRK05439
936154002589	Pantothenate kinase (PanK) catalyzes the phosphorylation of pantothenic acid to form 4'-phosphopantothenic, which is the first of five steps in coenzyme A (CoA) biosynthetic pathway. The reaction carried out by this enzyme is a key regulatory point...; Region: PanK; cd02025
936154002590	CoA-binding site [chemical binding]; other site
936154002591	Mg2+-binding site [ion binding]; other site
936154002592	30S ribosomal protein S20; Reviewed; Region: rpsT; PRK00239
936154002593	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
936154002594	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
936154002595	dimer interface [polypeptide binding]; other site
936154002596	phosphorylation site [posttranslational modification]
936154002597	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
936154002598	ATP binding site [chemical binding]; other site
936154002599	Mg2+ binding site [ion binding]; other site
936154002600	G-X-G motif; other site
936154002601	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
936154002602	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
936154002603	active site
936154002604	phosphorylation site [posttranslational modification]
936154002605	intermolecular recognition site; other site
936154002606	dimerization interface [polypeptide binding]; other site
936154002607	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
936154002608	DNA binding site [nucleotide binding]
936154002609	Peptidase M1 Aminopeptidase N family incudes tricorn interacting factor F3, Endoplasmic reticulum aminopeptidase 1 (ERAP1), Aminopeptidase Q (APQ); Region: M1_APN_2; cd09601
936154002610	Aminopeptidase N [Amino acid transport and metabolism]; Region: PepN; COG0308
936154002611	Zn binding site [ion binding]; other site
936154002612	phosphate transport system regulatory protein PhoU; Region: phoU_full; TIGR02135
936154002613	PhoU domain; Region: PhoU; pfam01895
936154002614	PhoU domain; Region: PhoU; pfam01895
936154002615	phosphate transporter ATP-binding protein; Provisional; Region: PRK14239
936154002616	ATP-binding cassette domain of the phosphate transport system; Region: ABC_PstB_phosphate_transporter; cd03260
936154002617	Walker A/P-loop; other site
936154002618	ATP binding site [chemical binding]; other site
936154002619	Q-loop/lid; other site
936154002620	ABC transporter signature motif; other site
936154002621	Walker B; other site
936154002622	D-loop; other site
936154002623	H-loop/switch region; other site
936154002624	ATP-binding cassette domain of the phosphate transport system; Region: ABC_PstB_phosphate_transporter; cd03260
936154002625	Q-loop/lid; other site
936154002626	ABC transporter signature motif; other site
936154002627	Walker B; other site
936154002628	D-loop; other site
936154002629	ABC-type phosphate transport system, permease component [Inorganic ion transport and metabolism]; Region: PstA; COG0581
936154002630	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
936154002631	dimer interface [polypeptide binding]; other site
936154002632	conserved gate region; other site
936154002633	putative PBP binding loops; other site
936154002634	ABC-ATPase subunit interface; other site
936154002635	ABC-type phosphate transport system, permease component [Inorganic ion transport and metabolism]; Region: PstC; COG0573
936154002636	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
936154002637	dimer interface [polypeptide binding]; other site
936154002638	conserved gate region; other site
936154002639	putative PBP binding loops; other site
936154002640	ABC-ATPase subunit interface; other site
936154002641	PBP superfamily domain; Region: PBP_like_2; cl17296
936154002642	Inositol-monophosphatase-like domains. This family of phosphatases is dependent on bivalent metal ions such as Mg++, and many members are inhibited by Li+ (which is thought to displace a bivalent ion in the active site). Substrates include fructose-1; Region: IMPase_like; cd01637
936154002643	Arsenate Reductase (ArsC) family, Spx subfamily; Spx is a unique RNA polymerase (RNAP)-binding protein present in bacilli and some mollicutes. It inhibits transcription by binding to the C-terminal domain of the alpha subunit of RNAP, disrupting complex...; Region: ArsC_Spx; cd03032
936154002644	ArsC family; Region: ArsC; pfam03960
936154002645	putative catalytic residues [active]
936154002646	thiol/disulfide switch; other site
936154002647	Uncharacterized protein family (UPF0223); Region: UPF0223; cl11484
936154002648	Riboflavin kinase; Region: Flavokinase; pfam01687
936154002649	tRNA pseudouridine synthase B; Provisional; Region: truB; PRK02484
936154002650	Pseudouridine synthase, Escherichia coli TruB like; Region: PseudoU_synth_EcTruB; cd02573
936154002651	RNA binding site [nucleotide binding]; other site
936154002652	active site
936154002653	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4487
936154002654	Uncharacterized protein conserved in bacteria (DUF2130); Region: DUF2130; pfam09903
936154002655	Predicted membrane protein [Function unknown]; Region: COG4129
936154002656	Bacterial protein of unknown function (DUF939); Region: DUF939; pfam06081
936154002657	DUF939 C-terminal domain; Region: DUF939_C; pfam11728
936154002658	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
936154002659	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
936154002660	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
936154002661	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
936154002662	Walker A/P-loop; other site
936154002663	ATP binding site [chemical binding]; other site
936154002664	Q-loop/lid; other site
936154002665	ABC transporter signature motif; other site
936154002666	Walker B; other site
936154002667	D-loop; other site
936154002668	H-loop/switch region; other site
936154002669	Peroxiredoxin (PRX) family, Atypical 2-cys PRX subfamily; composed of PRXs containing peroxidatic and resolving cysteines, similar to the homodimeric thiol specific antioxidant (TSA) protein also known as TRX-dependent thiol peroxidase (Tpx). Tpx is a...; Region: PRX_Atyp2cys; cd03014
936154002670	dimer interface [polypeptide binding]; other site
936154002671	catalytic triad [active]
936154002672	peroxidatic and resolving cysteines [active]
936154002673	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
936154002674	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
936154002675	DNA-binding site [nucleotide binding]; DNA binding site
936154002676	TrkA-C domain; Region: TrkA_C; pfam02080
936154002677	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1302
936154002678	CsbD-like; Region: CsbD; pfam05532
936154002679	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1302
936154002680	ATP-dependent DNA helicase PcrA; Region: pcrA; TIGR01073
936154002681	Part of AAA domain; Region: AAA_19; pfam13245
936154002682	Family description; Region: UvrD_C_2; pfam13538
936154002683	Na+/alanine symporter [Amino acid transport and metabolism]; Region: AlsT; COG1115
936154002684	Sodium:alanine symporter family; Region: Na_Ala_symp; cl00548
936154002685	Predicted Co/Zn/Cd cation transporters [Inorganic ion transport and metabolism]; Region: MMT1; COG0053
936154002686	Cation efflux family; Region: Cation_efflux; pfam01545
936154002687	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
936154002688	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
936154002689	substrate binding pocket [chemical binding]; other site
936154002690	membrane-bound complex binding site; other site
936154002691	hinge residues; other site
936154002692	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
936154002693	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
936154002694	Walker A/P-loop; other site
936154002695	ATP binding site [chemical binding]; other site
936154002696	Q-loop/lid; other site
936154002697	ABC transporter signature motif; other site
936154002698	Walker B; other site
936154002699	D-loop; other site
936154002700	H-loop/switch region; other site
936154002701	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
936154002702	dimer interface [polypeptide binding]; other site
936154002703	conserved gate region; other site
936154002704	ABC-ATPase subunit interface; other site
936154002705	Uncharacterized Zn-ribbon-containing protein involved in phosphonate metabolism [Inorganic ion transport and metabolism]; Region: PhnA; COG2824
936154002706	PhnA Zinc-Ribbon; Region: PhnA_Zn_Ribbon; pfam08274
936154002707	PhnA protein; Region: PhnA; pfam03831
936154002708	mannitol-1-phosphate 5-dehydrogenase; Provisional; Region: PRK02318
936154002709	Mannitol dehydrogenase Rossmann domain; Region: Mannitol_dh; pfam01232
936154002710	Mannitol dehydrogenase C-terminal domain; Region: Mannitol_dh_C; pfam08125
936154002711	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
936154002712	active site
936154002713	phosphorylation site [posttranslational modification]
936154002714	Transcriptional antiterminator [Transcription]; Region: BglG; COG3711
936154002715	Sugar-specific transcriptional regulator TrmB; Region: TrmB; cl17775
936154002716	HTH domain; Region: HTH_11; pfam08279
936154002717	PTS_IIB_bgl_like: the PTS (phosphotransferase system) IIB domain of a family of sensory systems composed of a membrane-bound sugar-sensor (similar to BglF) and a transcription antiterminator (similar to BglG) which regulate expression of genes involved...; Region: PTS_IIB_bgl_like; cd05568
936154002718	active site
936154002719	P-loop; other site
936154002720	phosphorylation site [posttranslational modification]
936154002721	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cl00163
936154002722	Phosphotransferase system, mannitol-specific IIBC component [Carbohydrate transport and metabolism]; Region: MtlA; COG2213
936154002723	PTS system, mannitol-specific IIC component; Region: mtlA; TIGR00851
936154002724	PTS_IIB_mannitol: subunit IIB of enzyme II (EII) of the mannitol-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is a mannitol-specific permease with two cytoplasmic domains (IIA and IIB) and a transmembrane...; Region: PTS_IIB_mannitol; cd05567
936154002725	active site
936154002726	P-loop; other site
936154002727	phosphorylation site [posttranslational modification]
936154002728	PTS_IIB_mannitol: subunit IIB of enzyme II (EII) of the mannitol-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is a mannitol-specific permease with two cytoplasmic domains (IIA and IIB) and a transmembrane...; Region: PTS_IIB_mannitol; cd05567
936154002729	active site
936154002730	P-loop; other site
936154002731	phosphorylation site [posttranslational modification]
936154002732	glucosamine--fructose-6-phosphate aminotransferase; Reviewed; Region: PRK00331
936154002733	Glutamine amidotransferases class-II (Gn-AT)_GFAT-type. This domain is found at the N-terminus of glucosamine-6P synthase (GlmS, or GFAT in humans).  The glutaminase domain catalyzes amide nitrogen transfer from glutamine to the appropriate substrate. In...; Region: GFAT; cd00714
936154002734	glutaminase active site [active]
936154002735	SIS (Sugar ISomerase) domain repeat 1 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_1; cd05008
936154002736	dimer interface [polypeptide binding]; other site
936154002737	active site
936154002738	SIS (Sugar ISomerase) domain repeat 2 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_2; cd05009
936154002739	dimer interface [polypeptide binding]; other site
936154002740	active site
936154002741	signal peptidase I, bacterial type; Region: sigpep_I_bact; TIGR02227
936154002742	The S24, S26 LexA/signal peptidase superfamily contains LexA-related and type I signal peptidase families. The S24 LexA protein domains include: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC 3.4.21.88), the...; Region: Peptidase_S24_S26; cl10465
936154002743	pyruvate kinase; Provisional; Region: PRK05826
936154002744	Pyruvate kinase (PK):  Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low...; Region: Pyruvate_Kinase; cl17342
936154002745	domain interfaces; other site
936154002746	active site
936154002747	6-phosphofructokinase; Provisional; Region: PRK03202
936154002748	active site
936154002749	ADP/pyrophosphate binding site [chemical binding]; other site
936154002750	fructose-1,6-bisphosphate binding site; other site
936154002751	dimerization interface [polypeptide binding]; other site
936154002752	allosteric effector site; other site
936154002753	DNA polymerase III DnaE; Reviewed; Region: dnaE; PRK07279
936154002754	Polymerase and Histidinol Phosphatase domain of alpha-subunit of bacterial polymerase III; Region: PHP_PolIIIA; cd07431
936154002755	active site
936154002756	PHP Thumb interface [polypeptide binding]; other site
936154002757	DnaE_OBF: A subfamily of OB folds corresponding to the C-terminal OB-fold nucleic acid binding domain of Thermus aquaticus and Escherichia coli type C replicative DNA polymerase III alpha subunit (DnaE). The DNA polymerase holoenzyme of E. coli contains...; Region: DnaE_OBF; cd04485
936154002758	generic binding surface I; other site
936154002759	generic binding surface II; other site
936154002760	Predicted transcriptional regulators [Transcription]; Region: COG1725
936154002761	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
936154002762	DNA-binding site [nucleotide binding]; DNA binding site
936154002763	ABC-type Na+ transport system, ATPase component [Energy production and conversion / Inorganic ion transport and metabolism]; Region: NatA; COG4555
936154002764	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
936154002765	Walker A/P-loop; other site
936154002766	ATP binding site [chemical binding]; other site
936154002767	Q-loop/lid; other site
936154002768	ABC transporter signature motif; other site
936154002769	Walker B; other site
936154002770	D-loop; other site
936154002771	H-loop/switch region; other site
936154002772	Uncharacterized conserved protein [Function unknown]; Region: COG0398
936154002773	Domain of unknown function (DUF3825); Region: DUF3825; pfam12873
936154002774	CsbD-like; Region: CsbD; pfam05532
936154002775	CHAP domain; Region: CHAP; cl17642
936154002776	Peptidoglycan recognition proteins (PGRPs) are pattern recognition receptors that bind, and in certain cases, hydrolyze peptidoglycans (PGNs) of bacterial cell walls. PGRPs have been divided into three classes: short PGRPs (PGRP-S), that are small (20...; Region: PGRP; cd06583
936154002777	amidase catalytic site [active]
936154002778	Zn binding residues [ion binding]; other site
936154002779	substrate binding site [chemical binding]; other site
936154002780	Protein of unknown function (DUF1366); Region: DUF1366; pfam07104
936154002781	Siphovirus protein of unknown function (DUF859); Region: DUF859; pfam05895
936154002782	ATP synthase subunit D; Region: ATP-synt_D; cl00613
936154002783	The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature; Region: BAR; cl12013
936154002784	tape measure domain; Region: tape_meas_nterm; TIGR02675
936154002785	CHAP domain; Region: CHAP; pfam05257
936154002786	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
936154002787	N-acetyl-D-glucosamine binding site [chemical binding]; other site
936154002788	catalytic residue [active]
936154002789	Protein of unknown function (DUF1268); Region: DUF1268; pfam06896
936154002790	Phage major tail protein; Region: Phage_tail; pfam04630
936154002791	Protein of unknown function (DUF806); Region: DUF806; pfam05657
936154002792	Bacteriophage protein of unknown function (DUF646); Region: DUF646; pfam04883
936154002793	phage major capsid protein, HK97 family; Region: major_cap_HK97; TIGR01554
936154002794	Phage capsid family; Region: Phage_capsid; pfam05065
936154002795	Caseinolytic protease (ClpP) is an ATP-dependent, highly conserved serine protease; Region: S14_ClpP_1; cd07016
936154002796	oligomer interface [polypeptide binding]; other site
936154002797	active site residues [active]
936154002798	Phage portal protein; Region: Phage_portal; pfam04860
936154002799	Phage-related protein [Function unknown]; Region: COG4695
936154002800	Phage Terminase; Region: Terminase_1; pfam03354
936154002801	Phage terminase, small subunit; Region: Terminase_4; cl01525
936154002802	phage transcriptional activator, RinA family; Region: phage_rinA; TIGR01636
936154002803	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
936154002804	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
936154002805	non-specific DNA binding site [nucleotide binding]; other site
936154002806	salt bridge; other site
936154002807	sequence-specific DNA binding site [nucleotide binding]; other site
936154002808	Protein of unknown function (DUF1642); Region: DUF1642; pfam07852
936154002809	Protein of unknwon function (DUF3310); Region: DUF3310; pfam11753
936154002810	Superfamily II DNA/RNA helicases, SNF2 family [Transcription / DNA replication, recombination, and repair]; Region: HepA; COG0553
936154002811	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
936154002812	ATP binding site [chemical binding]; other site
936154002813	putative Mg++ binding site [ion binding]; other site
936154002814	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cl17351
936154002815	nucleotide binding region [chemical binding]; other site
936154002816	ATP-binding site [chemical binding]; other site
936154002817	VRR-NUC domain; Region: VRR_NUC; pfam08774
936154002818	D5 N terminal like; Region: D5_N; smart00885
936154002819	phage/plasmid primase, P4 family, C-terminal domain; Region: primase_Cterm; TIGR01613
936154002820	Poxvirus D5 protein-like; Region: Pox_D5; pfam03288
936154002821	Polymerase I functions primarily to fill DNA gaps that arise during DNA repair, recombination and replication; Region: DNA_pol_A_pol_I_A; cd08642
936154002822	active site
936154002823	DNA binding site [nucleotide binding]
936154002824	catalytic site [active]
936154002825	Protein of unknown function (DUF2815); Region: DUF2815; pfam10991
936154002826	Protein of unknown function (DUF2800); Region: DUF2800; pfam10926
936154002827	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
936154002828	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
936154002829	non-specific DNA binding site [nucleotide binding]; other site
936154002830	salt bridge; other site
936154002831	sequence-specific DNA binding site [nucleotide binding]; other site
936154002832	tyrosine recombinase XerC; Region: recomb_XerC; TIGR02224
936154002833	phiLC3 phage and phage-related integrases, site-specific recombinases, DNA breaking-rejoining enzymes, C-terminal catalytic domain. This CD includes various bacterial (mainly gram positive) and phage integrases, including those similar to Lactococcus...; Region: INT_phiLC3_C; cd01189
936154002834	Int/Topo IB signature motif; other site
936154002835	Domain of Unknown Function with PDB structure (DUF3862); Region: DUF3862; pfam12978
936154002836	30S ribosomal protein S1; Reviewed; Region: rpsA; PRK06676
936154002837	S1_RPS1_repeat_ec1_hs1: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture...; Region: S1_RPS1_repeat_ec1_hs1; cd05687
936154002838	RNA binding site [nucleotide binding]; other site
936154002839	S1_RPS1_repeat_ec2_hs2: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture...; Region: S1_RPS1_repeat_ec2_hs2; cd04465
936154002840	RNA binding site [nucleotide binding]; other site
936154002841	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
936154002842	RNA binding site [nucleotide binding]; other site
936154002843	S1_RPS1_repeat_hs4: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_hs4; cd05692
936154002844	RNA binding site [nucleotide binding]; other site
936154002845	Protein of unknown function (DUF2969); Region: DUF2969; pfam11184
936154002846	branched-chain amino acid aminotransferase; Provisional; Region: PRK13357
936154002847	BCAT_beta_family: Branched-chain aminotransferase catalyses the transamination of the branched-chain amino acids  leusine, isoleucine and valine to their respective alpha-keto acids, alpha-ketoisocaproate, alpha-keto-beta-methylvalerate and...; Region: BCAT_beta_family; cd01557
936154002848	homodimer interface [polypeptide binding]; other site
936154002849	substrate-cofactor binding pocket; other site
936154002850	catalytic residue [active]
936154002851	DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes...; Region: TOP4c; cl00148
936154002852	primary dimer interface [polypeptide binding]; other site
936154002853	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
936154002854	DNA topoisomerase IV, B subunit, Gram-positive; Region: parE_Gpos; TIGR01058
936154002855	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
936154002856	Mg2+ binding site [ion binding]; other site
936154002857	G-X-G motif; other site
936154002858	TopoIIA_Trans_DNA_gyrase: Transducer domain, having a ribosomal S5 domain 2-like fold, of the type found in proteins of the type IIA family of DNA topoisomerases similar to the B subunits of E. coli DNA gyrase and E. coli Topoisomerase IV which are; Region: TopoII_Trans_DNA_gyrase; cd00822
936154002859	anchoring element; other site
936154002860	dimer interface [polypeptide binding]; other site
936154002861	ATP binding site [chemical binding]; other site
936154002862	TOPRIM_TopoIIA_GyrB: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in proteins of the type IIA family of DNA topoisomerases similar to the Escherichia coli GyrB subunit. TopoIIA enzymes cut both strands of the...; Region: TOPRIM_TopoIIA_GyrB; cd03366
936154002863	active site
936154002864	putative metal-binding site [ion binding]; other site
936154002865	DNA gyrase B subunit, carboxyl terminus; Region: DNA_gyraseB_C; pfam00986
936154002866	putative glycerol-3-phosphate acyltransferase PlsY; Provisional; Region: PRK00220
936154002867	dihydroorotase; Validated; Region: pyrC; PRK09357
936154002868	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
936154002869	Dihydroorotase (DHOase), subgroup IIa; DHOases catalyze the reversible interconversion of carbamoyl aspartate to dihydroorotate, a key reaction in pyrimidine biosynthesis. This subgroup also contains proteins that lack the active site, like unc-33, a C; Region: DHOase_IIa; cd01317
936154002870	active site
936154002871	Family 1 of Uracil-DNA glycosylase (UDG) enzymes; Region: UDG_F1; cd10027
936154002872	ligand binding site [chemical binding]; other site
936154002873	active site
936154002874	UGI interface [polypeptide binding]; other site
936154002875	catalytic site [active]
936154002876	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
936154002877	dimer interface [polypeptide binding]; other site
936154002878	conserved gate region; other site
936154002879	putative PBP binding loops; other site
936154002880	ABC-ATPase subunit interface; other site
936154002881	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
936154002882	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
936154002883	substrate binding pocket [chemical binding]; other site
936154002884	membrane-bound complex binding site; other site
936154002885	hinge residues; other site
936154002886	amidase; Provisional; Region: PRK06529
936154002887	Amidase; Region: Amidase; cl11426
936154002888	PhosphatidylEthanolamine-Binding Protein (PEBP) domain present in bacteria and archaea; Region: PEBP_bact_arch; cd00865
936154002889	substrate binding site [chemical binding]; other site
936154002890	Protein of unknown function (DUF1398); Region: DUF1398; cl11576
936154002891	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
936154002892	Coenzyme A binding pocket [chemical binding]; other site
936154002893	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
936154002894	active site
936154002895	Orotidine 5'-phosphate decarboxylase (ODCase) is a dimeric enzyme that decarboxylates orotidine 5'-monophosphate (OMP) to form uridine 5'-phosphate (UMP), an essential step in the pyrimidine biosynthetic pathway. In mammals, UMP synthase...; Region: OMP_decarboxylase_like; cd04725
936154002896	active site
936154002897	dimer interface [polypeptide binding]; other site
936154002898	UDP-glucose 6-dehydrogenase; Provisional; Region: PRK15057
936154002899	NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; Region: NAD_Gly3P_dh_N; pfam01210
936154002900	UDP-glucose/GDP-mannose dehydrogenase family, central domain; Region: UDPG_MGDP_dh; pfam00984
936154002901	UDP binding domain; Region: UDPG_MGDP_dh_C; smart00984
936154002902	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
936154002903	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
936154002904	NAD(P) binding site [chemical binding]; other site
936154002905	active site
936154002906	Acetyltransferase (isoleucine patch superfamily) [General function prediction only]; Region: WbbJ; COG0110
936154002907	Xenobiotic acyltransferase (XAT): The XAT class of hexapeptide acyltransferases is composed of a large number of microbial enzymes that catalyze the CoA-dependent acetylation of a variety of hydroxyl-bearing acceptors such as chloramphenicol and...; Region: LbH_XAT; cd03349
936154002908	trimer interface [polypeptide binding]; other site
936154002909	active site
936154002910	substrate binding site [chemical binding]; other site
936154002911	CoA binding site [chemical binding]; other site
936154002912	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
936154002913	potential frameshift: common BLAST hit: gi|90961966|ref|YP_535882.1| glycosyltransferase
936154002914	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
936154002915	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
936154002916	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
936154002917	This family is most closely related to the GT1 family of glycosyltransferases. cap1E in Streptococcus pneumoniae is required for the synthesis of type 1 capsular polysaccharides; Region: GT1_cap1E_like; cd03808
936154002918	putative ADP-binding pocket [chemical binding]; other site
936154002919	Putative Acyltransferase (AT), Left-handed parallel beta-Helix (LbH) domain; This group is composed of mostly uncharacterized proteins containing an N-terminal helical subdomain followed by a LbH domain. The alignment contains 6 turns, each containing...; Region: LbH_AT_putative; cd03360
936154002920	sugar O-acyltransferase, sialic acid O-acetyltransferase NeuD family; Region: NeuD_NnaD; TIGR03570
936154002921	putative trimer interface [polypeptide binding]; other site
936154002922	putative CoA binding site [chemical binding]; other site
936154002923	Bacterial sugar transferase; Region: Bac_transf; pfam02397
936154002924	aminotransferase, LLPSF_NHT_00031 family; Region: NHT_00031; TIGR04181
936154002925	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
936154002926	inhibitor-cofactor binding pocket; inhibition site
936154002927	pyridoxal 5'-phosphate binding site [chemical binding]; other site
936154002928	catalytic residue [active]
936154002929	Predicted nucleoside-diphosphate sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: COG1086
936154002930	UDP-Glcnac (UDP-linked N-acetylglucosamine) inverting 4,6-dehydratase, extended (e) SDRs; Region: UDP_invert_4-6DH_SDR_e; cd05237
936154002931	NAD(P) binding site [chemical binding]; other site
936154002932	homodimer interface [polypeptide binding]; other site
936154002933	substrate binding site [chemical binding]; other site
936154002934	active site
936154002935	capsular exopolysaccharide family; Region: eps_fam; TIGR01007
936154002936	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
936154002937	polysaccharide export protein, MPA1 family, Gram-positive type; Region: polys_exp_MPA1; TIGR01006
936154002938	Capsular polysaccharide biosynthesis protein [Cell envelope biogenesis, outer membrane]; Region: COG3944
936154002939	Capsular polysaccharide biosynthesis protein [Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: CapC; COG4464
936154002940	DNA polymerase processivity factor; Region: DNA_PPF; pfam02916
936154002941	Cell envelope-related transcriptional attenuator domain; Region: LytR_cpsA_psr; pfam03816
936154002942	Transcriptional regulator [Transcription]; Region: LysR; COG0583
936154002943	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
936154002944	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
936154002945	dimerization interface [polypeptide binding]; other site
936154002946	CRISPR/Cas system-associated protein Csm6; Region: Csm6_III-A; cl09873
936154002947	purine nucleoside phosphorylase; Reviewed; Region: deoD; PRK05819
936154002948	Uridine phosphorylase [Nucleotide transport and metabolism]; Region: Udp; COG2820
936154002949	purine nucleoside phosphorylase; Provisional; Region: PRK08202
936154002950	Arsenate Reductase (ArsC) family, ArsC subfamily; arsenic reductases similar to that encoded by arsC on the R733 plasmid of Escherichia coli. E. coli ArsC catalyzes the reduction of arsenate [As(V)] to arsenite [As(III)], the first step in the...; Region: ArsC_ArsC; cd03034
936154002951	ArsC family; Region: ArsC; pfam03960
936154002952	catalytic residues [active]
936154002953	phosphopentomutase; Provisional; Region: PRK05362
936154002954	Metalloenzyme superfamily; Region: Metalloenzyme; pfam01676
936154002955	RPI_A: Ribose 5-phosphate isomerase type A (RPI_A) subfamily; RPI catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate, the first step of the non-oxidative branch of the pentose phosphate pathway. This reaction leads to the...; Region: RPI_A; cd01398
936154002956	tetramer (dimer of dimers) interface [polypeptide binding]; other site
936154002957	active site
936154002958	dimer interface [polypeptide binding]; other site
936154002959	tRNA modification GTPase TrmE; Reviewed; Region: trmE; PRK05291
936154002960	GTP-binding protein TrmE N-terminus; Region: TrmE_N; pfam10396
936154002961	trmE is a tRNA modification GTPase; Region: trmE; cd04164
936154002962	G1 box; other site
936154002963	GTP/Mg2+ binding site [chemical binding]; other site
936154002964	Switch I region; other site
936154002965	G2 box; other site
936154002966	Switch II region; other site
936154002967	G3 box; other site
936154002968	G4 box; other site
936154002969	G5 box; other site
936154002970	Catalytic cysteine-containing C-terminus of GTPase, MnmE; Region: GTPase_Cys_C; pfam12631
936154002971	dipeptidase PepV; Reviewed; Region: PRK07318
936154002972	M20 Peptidase Xaa-His dipeptidase (PepV) degrades hydrophobic dipeptides; Region: M20_PepV; cd03888
936154002973	active site
936154002974	metal binding site [ion binding]; metal-binding site
936154002975	Proteins of this family catalyze the reduction of flavin or nitrocompounds using NAD(P)H as electron donor in a obligatory two-electron transfer,  utilizing FMN or FAD as cofactor. They are often found to be homodimers. Enzymes of this family are...; Region: Nitro_FMN_reductase; cl00514
936154002976	dimer interface [polypeptide binding]; other site
936154002977	excinuclease ABC subunit C; Validated; Region: uvrC; PRK00558
936154002978	Catalytic GIY-YIG domain of nucleotide excision repair endonucleases UvrC, Cho, and similar proteins; Region: GIY-YIG_UvrC_Cho; cd10434
936154002979	GIY-YIG motif/motif A; other site
936154002980	active site
936154002981	catalytic site [active]
936154002982	putative DNA binding site [nucleotide binding]; other site
936154002983	metal binding site [ion binding]; metal-binding site
936154002984	UvrB/uvrC motif; Region: UVR; pfam02151
936154002985	UvrC Helix-hairpin-helix N-terminal; Region: UvrC_HhH_N; pfam08459
936154002986	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
936154002987	putative substrate translocation pore; other site
936154002988	Major Facilitator Superfamily; Region: MFS_1; pfam07690
936154002989	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
936154002990	haloacid dehalogenase-like hydrolase; Region: Hydrolase_3; pfam08282
936154002991	active site
936154002992	motif I; other site
936154002993	motif II; other site
936154002994	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
936154002995	NAD-dependent aldehyde dehydrogenases [Energy production and conversion]; Region: PutA; COG1012
936154002996	Mycobacterium tuberculosis succinate-semialdehyde dehydrogenase 1-like; Region: ALDH_SSADH1_GabD1; cd07100
936154002997	NAD(P) binding site [chemical binding]; other site
936154002998	catalytic residues [active]
936154002999	HAD superfamily (subfamily IA) hydrolase, TIGR02254; Region: YjjG/YfnB
936154003000	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
936154003001	motif II; other site
936154003002	Putative intracellular protease/amidase [General function prediction only]; Region: ThiJ; COG0693
936154003003	Type 1 glutamine amidotransferase (GATase1)-like domain found in proteins similar to Escherichia coli Hsp31 protein; Region: GATase1_Hsp31_like; cd03141
936154003004	potential catalytic triad [active]
936154003005	conserved cys residue [active]
936154003006	Esterase/lipase [Lipid metabolism]; Region: Aes; COG0657
936154003007	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
936154003008	Predicted membrane protein [Function unknown]; Region: COG2855
936154003009	potential frameshift: common BLAST hit: gi|288905513|ref|YP_003430735.1| oxidoreductase, aldo/keto reductase
936154003010	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
936154003011	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
936154003012	active site
936154003013	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
936154003014	catalytic tetrad [active]
936154003015	Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit [Function unknown]; Region: COG0599
936154003016	Uncharacterized conserved protein, contains double-stranded beta-helix domain [Function unknown]; Region: COG1917
936154003017	Predicted transcriptional regulators [Transcription]; Region: SoxR; COG0789
936154003018	Helix-Turn-Helix DNA binding domain of the MerR-like transcription regulators YyaN and YraB; Region: HTH_YyaN; cd01109
936154003019	DNA binding residues [nucleotide binding]
936154003020	putative dimer interface [polypeptide binding]; other site
936154003021	formaldehyde dehydrogenase (FDH)-like; Region: FDH_like_ADH3; cd08287
936154003022	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
936154003023	catalytic Zn binding site [ion binding]; other site
936154003024	NAD(P) binding site [chemical binding]; other site
936154003025	structural Zn binding site [ion binding]; other site
936154003026	NADH(P)-binding; Region: NAD_binding_10; pfam13460
936154003027	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
936154003028	active site
936154003029	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
936154003030	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
936154003031	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
936154003032	active site
936154003033	catalytic tetrad [active]
936154003034	Lipase.  Lipases are esterases that can hydrolyze long-chain acyl-triglycerides into di- and monoglycerides, glycerol, and free fatty acids at a water/lipid interface. A typical feature of lipases is "interfacial activation", the process of...; Region: Lipase; cl14883
936154003035	Lipase.  Lipases are esterases that can hydrolyze long-chain acyl-triglycerides into di- and monoglycerides, glycerol, and free fatty acids at a water/lipid interface. A typical feature of lipases is "interfacial activation", the process of...; Region: Lipase; cd00741
936154003036	nucleophilic elbow; other site
936154003037	nucleophilic elbow; other site
936154003038	catalytic triad; other site
936154003039	catalytic triad; other site
936154003040	Acetyltransferases [General function prediction only]; Region: RimI; COG0456
936154003041	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
936154003042	Coenzyme A binding pocket [chemical binding]; other site
936154003043	Predicted HD superfamily hydrolase [General function prediction only]; Region: COG1418
936154003044	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
936154003045	Zn2+ binding site [ion binding]; other site
936154003046	Mg2+ binding site [ion binding]; other site
936154003047	GTP-binding protein LepA; Provisional; Region: PRK05433
936154003048	LepA also known as Elongation Factor 4 (EF4); Region: LepA; cd01890
936154003049	G1 box; other site
936154003050	putative GEF interaction site [polypeptide binding]; other site
936154003051	GTP/Mg2+ binding site [chemical binding]; other site
936154003052	Switch I region; other site
936154003053	G2 box; other site
936154003054	G3 box; other site
936154003055	Switch II region; other site
936154003056	G4 box; other site
936154003057	G5 box; other site
936154003058	lepA_II: This subfamily represents the domain II of LepA, a GTP-binding protein localized in the cytoplasmic membrane. The N-terminal domain of LepA shares regions of homology to translation factors. In terms of interaction with the ribosome, EF-G, EF-Tu...; Region: lepA_II; cd03699
936154003059	lepA_C: This family represents the C-terminal region of LepA, a GTP-binding protein localized in the cytoplasmic membrane.   LepA is ubiquitous in Bacteria and Eukaryota (e.g. Saccharomyces cerevisiae GUF1p), but is missing from Archaea. LepA exhibits...; Region: lepA_C; cd03709
936154003060	GTP-binding protein LepA C-terminus; Region: LepA_C; pfam06421
936154003061	Nucleoside diphosphate kinase Group I (NDPk_I)-like: NDP kinase domains are present in a large family of structurally and functionally conserved proteins from bacteria to humans that generally catalyze the transfer of gamma-phosphates of a nucleoside...; Region: NDPk_I; cd04413
936154003062	active site
936154003063	multimer interface [polypeptide binding]; other site
936154003064	HAD-superfamily subfamily IIA hydrolase, TIGR01457; Region: HAD-SF-IIA-hyp2
936154003065	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
936154003066	active site
936154003067	motif I; other site
936154003068	motif II; other site
936154003069	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
936154003070	Acyl-ACP thioesterase; Region: Acyl-ACP_TE; pfam01643
936154003071	4-hydroxybenzoyl-CoA thioesterase (4HBT). Catalyzes the final step in the 4-chlorobenzoate degradation pathway in which 4-chlorobenzoate is converted to 4-hydroxybenzoate in certain soil-dwelling bacteria. 4HBT forms a homotetramer with four active sites; Region: 4HBT; cd00586
936154003072	active site
936154003073	4-hydroxybenzoyl-CoA thioesterase (4HBT). Catalyzes the final step in the 4-chlorobenzoate degradation pathway in which 4-chlorobenzoate is converted to 4-hydroxybenzoate in certain soil-dwelling bacteria. 4HBT forms a homotetramer with four active sites; Region: 4HBT; cd00586
936154003074	active site
936154003075	coproporphyrinogen III oxidase; Provisional; Region: PRK08446
936154003076	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
936154003077	FeS/SAM binding site; other site
936154003078	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
936154003079	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
936154003080	phosphoglucosamine mutase; Provisional; Region: glmM; PRK14316
936154003081	GlmM is a bacterial phosphoglucosamine mutase (PNGM) that belongs to the alpha-D-phosphohexomutase superfamily. It is required for the interconversion of glucosamine-6-phosphate and glucosamine-1-phosphate in the biosynthetic pathway of...; Region: GlmM; cd05802
936154003082	active site
936154003083	substrate binding site [chemical binding]; other site
936154003084	metal binding site [ion binding]; metal-binding site
936154003085	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4856
936154003086	YbbR-like protein; Region: YbbR; pfam07949
936154003087	Uncharacterized conserved protein [Function unknown]; Region: COG1624
936154003088	DisA bacterial checkpoint controller nucleotide-binding; Region: DisA_N; pfam02457
936154003089	UDP-N-acetylmuramyl tripeptide synthase [Cell envelope biogenesis, outer membrane]; Region: MurE; COG0769
936154003090	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
936154003091	Domain of unknown function (DUF1727); Region: DUF1727; pfam08353
936154003092	Type 1 glutamine amidotransferase (GATase1) domain found in Cobyric Acid Synthase (CobQ); Region: GATase1_CobQ; cd01750
936154003093	catalytic triad [active]
936154003094	Lipoate-protein ligase A [Coenzyme metabolism]; Region: LplA; COG0095
936154003095	lipoyltransferase and lipoate-protein ligase; Region: lipoyltrans; TIGR00545
936154003096	Bacterial lipoate protein ligase C-terminus; Region: Lip_prot_lig_C; pfam10437
936154003097	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
936154003098	E3 interaction surface; other site
936154003099	lipoyl attachment site [posttranslational modification]; other site
936154003100	dihydrolipoamide dehydrogenase; Region: lipoamide_DH; TIGR01350
936154003101	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
936154003102	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
936154003103	branched-chain alpha-keto acid dehydrogenase subunit E2; Reviewed; Region: PRK11856
936154003104	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
936154003105	E3 interaction surface; other site
936154003106	lipoyl attachment site [posttranslational modification]; other site
936154003107	e3 binding domain; Region: E3_binding; pfam02817
936154003108	e3 binding domain; Region: E3_binding; pfam02817
936154003109	2-oxoacid dehydrogenases acyltransferase (catalytic domain); Region: 2-oxoacid_dh; pfam00198
936154003110	Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit [Energy production and conversion]; Region: AcoB; COG0022
936154003111	Pyrimidine (PYR) binding domain of the beta subunits of the E1 components of human pyruvate dehydrogenase complex (E1- PDHc) and related proteins; Region: TPP_PYR_E1-PDHc-beta_like; cd07036
936154003112	alpha subunit interface [polypeptide binding]; other site
936154003113	TPP binding site [chemical binding]; other site
936154003114	heterodimer interface [polypeptide binding]; other site
936154003115	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
936154003116	Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit [Energy production and conversion]; Region: AcoA; COG1071
936154003117	Thiamine pyrophosphate (TPP) family, E1 of PDC_ADC_BCADC subfamily, TPP-binding module; composed of proteins similar to the E1 components of the human pyruvate dehydrogenase complex (PDC), the acetoin dehydrogenase complex (ADC) and the branched chain...; Region: TPP_E1_PDC_ADC_BCADC; cd02000
936154003118	tetramer interface [polypeptide binding]; other site
936154003119	TPP-binding site [chemical binding]; other site
936154003120	heterodimer interface [polypeptide binding]; other site
936154003121	phosphorylation loop region [posttranslational modification]
936154003122	ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only]; Region: Uup; COG0488
936154003123	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
936154003124	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
936154003125	Walker A/P-loop; other site
936154003126	ATP binding site [chemical binding]; other site
936154003127	Q-loop/lid; other site
936154003128	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
936154003129	ABC transporter signature motif; other site
936154003130	Walker B; other site
936154003131	D-loop; other site
936154003132	ABC transporter; Region: ABC_tran_2; pfam12848
936154003133	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
936154003134	Zinc-dependent metalloprotease, MMP_like subfamily. This group contains matrix metalloproteinases (MMPs), serralysins, and the astacin_like family of proteases; Region: ZnMc_MMP_like; cd04268
936154003135	active site
936154003136	S-formylglutathione hydrolase; Region: PLN02442
936154003137	Predicted esterase [General function prediction only]; Region: COG0627
936154003138	conserved hypothetical protein; Region: MG423; TIGR00649
936154003139	Metallo-beta-lactamase superfamily; Region: Lactamase_B; pfam00753
936154003140	RNA-metabolising metallo-beta-lactamase; Region: RMMBL; pfam07521
936154003141	ABC-type uncharacterized transport system, ATPase component [General function prediction only]; Region: PhnK; COG1101
936154003142	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
936154003143	Walker A/P-loop; other site
936154003144	ATP binding site [chemical binding]; other site
936154003145	Q-loop/lid; other site
936154003146	ABC transporter signature motif; other site
936154003147	Walker B; other site
936154003148	D-loop; other site
936154003149	H-loop/switch region; other site
936154003150	potential frameshift: common BLAST hit: gi|325978026|ref|YP_004287742.1|  ABC transporter permease
936154003151	Transmembrane subunit (TM) of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which are involved in the uptake of branched-chain amino acids (AAs), as well as TMs of transporters involved in the uptake of...; Region: TM_PBP1_branched-chain-AA_like; cd06574
936154003152	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
936154003153	TM-ABC transporter signature motif; other site
936154003154	Transmembrane subunit (TM) of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which are involved in the uptake of branched-chain amino acids (AAs), as well as TMs of transporters involved in the uptake of...; Region: TM_PBP1_branched-chain-AA_like; cl00454
936154003155	Type I periplasmic ligand-binding domain of uncharacterized ABC-type transport systems that are predicted to be involved in the uptake of amino acids, peptides, or inorganic ions; Region: PBP1_ABC_uncharacterized_transporter; cd06325
936154003156	zinc binding site [ion binding]; other site
936154003157	putative ligand binding site [chemical binding]; other site
936154003158	Fibronectin-binding protein A N-terminus (FbpA); Region: FbpA; pfam05833
936154003159	Domain of unknown function (DUF814); Region: DUF814; pfam05670
936154003160	Alpha-acetolactate decarboxylase; Region: AAL_decarboxy; pfam03306
936154003161	acetolactate synthase; Reviewed; Region: PRK08617
936154003162	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
936154003163	PYR/PP interface [polypeptide binding]; other site
936154003164	dimer interface [polypeptide binding]; other site
936154003165	TPP binding site [chemical binding]; other site
936154003166	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
936154003167	Thiamine pyrophosphate (TPP) enzyme family, TPP-binding module; found in many key metabolic enzymes which use TPP (also known as thiamine diphosphate) as a cofactor. These enzymes include, among others, the E1 components of the pyruvate, the acetoin and...; Region: TPP_enzymes; cl01629
936154003168	TPP-binding site [chemical binding]; other site
936154003169	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; COG0628
936154003170	Domain of unknown function DUF20; Region: UPF0118; pfam01594
936154003171	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429
936154003172	binding surface
936154003173	TPR motif; other site
936154003174	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
936154003175	binding surface
936154003176	TPR motif; other site
936154003177	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
936154003178	binding surface
936154003179	TPR motif; other site
936154003180	Anaphase-promoting complex, cyclosome, subunit 3; Region: Apc3; pfam12895
936154003181	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; COG0628
936154003182	MutT homolog-1 (MTH1) is a member of the Nudix hydrolase superfamily. MTH1, the mammalian counterpart of MutT, hydrolyzes oxidized purine nucleoside triphosphates, such as 8-oxo-dGTP and 2-hydroxy-ATP, to monophosphates, thereby preventing the...; Region: MTH1; cd03427
936154003183	putative active site [active]
936154003184	nucleotide binding site [chemical binding]; other site
936154003185	nudix motif; other site
936154003186	putative metal binding site [ion binding]; other site
936154003187	Lactonase, 7-bladed beta-propeller; Region: Lactonase; pfam10282
936154003188	dTDP-D-glucose 4,6-dehydratase [Cell envelope biogenesis, outer membrane]; Region: RfbB; COG1088
936154003189	dTDP-D-glucose 4,6-dehydratase, extended (e) SDRs; Region: dTDP_GD_SDR_e; cd05246
936154003190	NAD binding site [chemical binding]; other site
936154003191	substrate binding site [chemical binding]; other site
936154003192	homodimer interface [polypeptide binding]; other site
936154003193	active site
936154003194	dTDP-4-dehydrorhamnose 3,5-epimerase and related enzymes [Cell envelope biogenesis, outer membrane]; Region: RfbC; COG1898
936154003195	G1P_TT_short is the short form of glucose-1-phosphate thymidylyltransferase; Region: G1P_TT_short; cd02538
936154003196	glucose-1-phosphate thymidylyltransferase, short form; Region: rmlA; TIGR01207
936154003197	substrate binding site; other site
936154003198	tetramer interface; other site
936154003199	Glycine/D-amino acid oxidases (deaminating) [Amino acid transport and metabolism]; Region: DadA; COG0665
936154003200	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
936154003201	Predicted divalent heavy-metal cations transporter [Inorganic ion transport and metabolism]; Region: COG0428
936154003202	Uncharacterized conserved protein [Function unknown]; Region: COG0327
936154003203	NIF3 (NGG1p interacting factor 3); Region: NIF3; pfam01784
936154003204	Predicted SAM-dependent methyltransferase [General function prediction only]; Region: COG2384
936154003205	Family of unknown function (DUF633); Region: DUF633; pfam04816
936154003206	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
936154003207	endonuclease III; Region: ENDO3c; smart00478
936154003208	minor groove reading motif; other site
936154003209	helix-hairpin-helix signature motif; other site
936154003210	substrate binding pocket [chemical binding]; other site
936154003211	active site
936154003212	Putative primosome component and related proteins [DNA replication, recombination, and repair]; Region: DnaD; COG3935
936154003213	Replication initiation and membrane attachment; Region: DnaB_2; pfam07261
936154003214	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
936154003215	active site
936154003216	single-stranded-DNA-specific exonuclease RecJ; Region: recJ; TIGR00644
936154003217	DHH family; Region: DHH; pfam01368
936154003218	DHHA1 domain; Region: DHHA1; pfam02272
936154003219	Single-strand DNA-specific exonuclease, C terminal domain; Region: ssDNA-exonuc_C; pfam10141
936154003220	Short-chain dehydrogenases of various substrate specificities [General function prediction only]; Region: DltE; COG0300
936154003221	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
936154003222	NAD(P) binding site [chemical binding]; other site
936154003223	active site
936154003224	ribonuclease Z; Region: RNase_Z; TIGR02651
936154003225	Galactose-1-phosphate uridyl transferase, N-terminal domain; Region: GalP_UDP_transf; pfam01087
936154003226	GTP-binding protein HflX; Region: GTP_HflX; TIGR03156
936154003227	GTP-binding GTPase N-terminal; Region: GTP-bdg_N; pfam13167
936154003228	HflX GTPase family; Region: HflX; cd01878
936154003229	G1 box; other site
936154003230	GTP/Mg2+ binding site [chemical binding]; other site
936154003231	Switch I region; other site
936154003232	G2 box; other site
936154003233	G3 box; other site
936154003234	Switch II region; other site
936154003235	G4 box; other site
936154003236	G5 box; other site
936154003237	tRNA delta(2)-isopentenylpyrophosphate transferase [Translation, ribosomal structure and biogenesis]; Region: MiaA; COG0324
936154003238	tRNA delta(2)-isopentenylpyrophosphate transferase; Reviewed; Region: miaA; PRK00091
936154003239	C4-dicarboxylate transporters of the Tellurite-resistance/Dicarboxylate Transporter (TDT) family; Region: TDT_C4-dicarb_trans; cd09325
936154003240	Tellurite resistance protein and related permeases [Inorganic ion transport and metabolism]; Region: TehA; COG1275
936154003241	gating phenylalanine in ion channel; other site
936154003242	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
936154003243	metal-binding site [ion binding]
936154003244	Co/Zn/Cd efflux system component [Inorganic ion transport and metabolism]; Region: CzcD; COG1230
936154003245	putative rhodanese-related sulfurtransferase; Provisional; Region: PRK00142
936154003246	Member of the Rhodanese Homology Domain superfamily. This CD includes Escherichia coli YceA, Bacillus subtilis YbfQ, and similar uncharacterized proteins; Region: RHOD_YceA; cd01518
936154003247	active site residue [active]
936154003248	Protein of unknown function (DUF3650); Region: DUF3650; pfam12368
936154003249	Alanine dehydrogenase [Amino acid transport and metabolism]; Region: Ald; COG0686
936154003250	Alanine dehydrogenase NAD-binding and catalytic domains; Region: L-AlaDH; cd05305
936154003251	hexamer interface [polypeptide binding]; other site
936154003252	ligand binding site [chemical binding]; other site
936154003253	putative active site [active]
936154003254	NAD(P) binding site [chemical binding]; other site
936154003255	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
936154003256	glycogen/starch/alpha-glucan phosphorylases; Region: P_ylase; TIGR02093
936154003257	4-alpha-glucanotransferase; Provisional; Region: PRK14508
936154003258	Transcriptional regulators [Transcription]; Region: PurR; COG1609
936154003259	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
936154003260	DNA binding site [nucleotide binding]
936154003261	domain linker motif; other site
936154003262	Ligand-binding domain of uncharacterized transcription regulator ycjW which is a member of the LacI-GalR family repressors; Region: PBP1_ycjW_transcription_regulator_like; cd06294
936154003263	putative dimerization interface [polypeptide binding]; other site
936154003264	putative ligand binding site [chemical binding]; other site
936154003265	Bacterial extracellular solute-binding protein; Region: SBP_bac_8; pfam13416
936154003266	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
936154003267	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
936154003268	dimer interface [polypeptide binding]; other site
936154003269	conserved gate region; other site
936154003270	putative PBP binding loops; other site
936154003271	ABC-ATPase subunit interface; other site
936154003272	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
936154003273	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
936154003274	dimer interface [polypeptide binding]; other site
936154003275	conserved gate region; other site
936154003276	putative PBP binding loops; other site
936154003277	ABC-ATPase subunit interface; other site
936154003278	Alpha amylase catalytic domain found in archaeal and bacterial Alpha-amylases (also called 1,4-alpha-D-glucan-4-glucanohydrolase); Region: AmyAc_arch_bac_AmyA; cd11313
936154003279	Glycosidases [Carbohydrate transport and metabolism]; Region: AmyA; COG0366
936154003280	active site
936154003281	catalytic site [active]
936154003282	potential frameshift: common BLAST hit: gi|139473639|ref|YP_001128355.1| D-alanyl-lipoteichoic acid biosynthesis protein
936154003283	DltD central region; Region: DltD_M; pfam04918
936154003284	DltD C-terminal region; Region: DltD_C; pfam04914
936154003285	DltD N-terminal region; Region: DltD_N; pfam04915
936154003286	D-alanine--poly(phosphoribitol) ligase subunit 2; Validated; Region: PRK05087
936154003287	D-alanyl-lipoteichoic acid biosynthesis protein DltB; Region: LTA_dltB; TIGR04091
936154003288	D-alanine--poly(phosphoribitol) ligase subunit 1; Provisional; Region: PRK04813
936154003289	D-alanine:D-alanyl carrier protein ligase (DltA); Region: DltA; cd05945
936154003290	acyl-activating enzyme (AAE) consensus motif; other site
936154003291	AMP binding site [chemical binding]; other site
936154003292	excinuclease ABC subunit B; Provisional; Region: PRK05298
936154003293	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
936154003294	ATP binding site [chemical binding]; other site
936154003295	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
936154003296	nucleotide binding region [chemical binding]; other site
936154003297	ATP-binding site [chemical binding]; other site
936154003298	Ultra-violet resistance protein B; Region: UvrB; pfam12344
936154003299	UvrB/uvrC motif; Region: UVR; pfam02151
936154003300	potential frameshift: common BLAST hit: gi|222153290|ref|YP_002562467.1| glutamine ABC transporter glutamine-binding protein/permease
936154003301	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
936154003302	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
936154003303	substrate binding pocket [chemical binding]; other site
936154003304	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
936154003305	hinge residues; other site
936154003306	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
936154003307	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
936154003308	substrate binding pocket [chemical binding]; other site
936154003309	membrane-bound complex binding site; other site
936154003310	hinge residues; other site
936154003311	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
936154003312	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
936154003313	Walker A/P-loop; other site
936154003314	ATP binding site [chemical binding]; other site
936154003315	Q-loop/lid; other site
936154003316	ABC transporter signature motif; other site
936154003317	Walker B; other site
936154003318	D-loop; other site
936154003319	H-loop/switch region; other site
936154003320	ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only]; Region: Uup; COG0488
936154003321	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
936154003322	Phage capsid scaffolding protein (GPO) serine peptidase; Region: Phage_GPO; cl15838
936154003323	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
936154003324	Nicotinamide mononucleotide transporter; Region: NMN_transporter; cl01256
936154003325	GTPase CgtA; Reviewed; Region: obgE; PRK12297
936154003326	GTP1/OBG; Region: GTP1_OBG; pfam01018
936154003327	Obg GTPase; Region: Obg; cd01898
936154003328	G1 box; other site
936154003329	GTP/Mg2+ binding site [chemical binding]; other site
936154003330	Switch I region; other site
936154003331	G2 box; other site
936154003332	G3 box; other site
936154003333	Switch II region; other site
936154003334	G4 box; other site
936154003335	G5 box; other site
936154003336	Domain of unknown function (DUF1967); Region: DUF1967; pfam09269
936154003337	potential frameshift: common BLAST hit: gi|222153297|ref|YP_002562474.1| aminopeptidase PepS
936154003338	Leucyl aminopeptidase (aminopeptidase T) [Amino acid transport and metabolism]; Region: AmpS; COG2309
936154003339	Thermophilic metalloprotease (M29); Region: Peptidase_M29; pfam02073
936154003340	Leucyl aminopeptidase (aminopeptidase T) [Amino acid transport and metabolism]; Region: AmpS; COG2309
936154003341	uncharacterized bacterial subfamily of the Escherichia coli CorA-Salmonella typhimurium ZntB family; Region: EcCorA_ZntB-like_u1; cd12826
936154003342	Cl binding site [ion binding]; other site
936154003343	oligomer interface [polypeptide binding]; other site
936154003344	CorA-like Mg2+ transporter protein; Region: CorA; pfam01544
936154003345	16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases [Translation, ribosomal structure and biogenesis]; Region: RsuA; COG1187
936154003346	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
936154003347	RNA binding surface [nucleotide binding]; other site
936154003348	Pseudouridine synthase, Escherichia coli RsuA like; Region: PseudoU_synth_RsuA; cd02553
936154003349	active site
936154003350	uracil binding [chemical binding]; other site
936154003351	Predicted thioesterase [General function prediction only]; Region: COG5496
936154003352	benzoate transport; Region: 2A0115; TIGR00895
936154003353	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
936154003354	putative substrate translocation pore; other site
936154003355	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4868
936154003356	ABC-type uncharacterized transport system, permease component [General function prediction only]; Region: COG0390
936154003357	putative ABC transporter ATP-binding protein YbbL; Provisional; Region: PRK10247
936154003358	First domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain1; cd03225
936154003359	Walker A/P-loop; other site
936154003360	ATP binding site [chemical binding]; other site
936154003361	Q-loop/lid; other site
936154003362	ABC transporter signature motif; other site
936154003363	Walker B; other site
936154003364	D-loop; other site
936154003365	H-loop/switch region; other site
936154003366	potential frameshift: common BLAST hit: gi|328957921|ref|YP_004375307.1| transcriptional regulator-like protein
936154003367	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
936154003368	Transcriptional regulator [Transcription]; Region: LysR; COG0583
936154003369	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
936154003370	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
936154003371	dimerization interface [polypeptide binding]; other site
936154003372	acetyl-CoA acetyltransferase; Provisional; Region: PRK09052
936154003373	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
936154003374	dimer interface [polypeptide binding]; other site
936154003375	active site
936154003376	phenylacetate degradation probable enoyl-CoA hydratase paaB; Region: PaaB1; TIGR02280
936154003377	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
936154003378	substrate binding site [chemical binding]; other site
936154003379	oxyanion hole (OAH) forming residues; other site
936154003380	trimer interface [polypeptide binding]; other site
936154003381	butyryl-CoA:acetate CoA-transferase; Region: butyr_acet_CoA; TIGR03948
936154003382	Acetyl-CoA hydrolase/transferase N-terminal domain; Region: AcetylCoA_hydro; pfam02550
936154003383	Acetyl-CoA hydrolase/transferase C-terminal domain; Region: AcetylCoA_hyd_C; pfam13336
936154003384	Acyl-CoA dehydrogenase; Region: ACAD; cl09933
936154003385	acyl-coenzyme A oxidase; Region: PLN02526
936154003386	active site
936154003387	Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II [Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism]; Region: CaiC; COG0318
936154003388	VHS, ENTH and ANTH domain superfamily; composed of proteins containing a VHS, ENTH or ANTH domain. The VHS domain is present in Vps27 (Vacuolar Protein Sorting), Hrs (Hepatocyte growth factor-regulated tyrosine kinase substrate) and STAM (Signal...; Region: VHS_ENTH_ANTH; cl02544
936154003389	Bacterial Bile acid CoA ligases and similar proteins; Region: BACL_like; cd05929
936154003390	acyl-activating enzyme (AAE) consensus motif; other site
936154003391	putative AMP binding site [chemical binding]; other site
936154003392	putative active site [active]
936154003393	putative CoA binding site [chemical binding]; other site
936154003394	Nucleoside 2-deoxyribosyltransferase; Region: Nuc_deoxyrib_tr; pfam05014
936154003395	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
936154003396	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
936154003397	non-specific DNA binding site [nucleotide binding]; other site
936154003398	salt bridge; other site
936154003399	sequence-specific DNA binding site [nucleotide binding]; other site
936154003400	RibD C-terminal domain; Region: RibD_C; cl17279
936154003401	tRNA-dihydrouridine synthase [Translation, ribosomal structure and biogenesis]; Region: COG0042
936154003402	Dihydrouridine synthase-like (DUS-like) FMN-binding domain. Members of this family catalyze the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also...; Region: DUS_like_FMN; cd02801
936154003403	FMN binding site [chemical binding]; other site
936154003404	active site
936154003405	catalytic residues [active]
936154003406	substrate binding site [chemical binding]; other site
936154003407	SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase [Translation, ribosomal structure and biogenesis]; Region: TrmA; COG2265
936154003408	Predicted RNA-binding protein, contains TRAM domain [General function prediction only]; Region: COG3269
936154003409	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
936154003410	S-adenosylmethionine binding site [chemical binding]; other site
936154003411	Transcriptional regulator [Transcription]; Region: LytR; COG1316
936154003412	shikimate kinase; Reviewed; Region: aroK; PRK00131
936154003413	Shikimate kinase (SK) is the fifth enzyme in the shikimate pathway, a seven-step biosynthetic pathway which converts erythrose-4-phosphate to chorismic acid, found in bacteria, fungi and plants. Chorismic acid is a important intermediate in the synthesis...; Region: SK; cd00464
936154003414	ADP binding site [chemical binding]; other site
936154003415	magnesium binding site [ion binding]; other site
936154003416	putative shikimate binding site; other site
936154003417	3-phosphoshikimate 1-carboxyvinyltransferase; Provisional; Region: PRK02427
936154003418	EPSP synthase domain. 3-phosphoshikimate 1-carboxyvinyltransferase (5-enolpyruvylshikimate-3-phosphate synthase) (EC 2.5.1.19) catalyses the reaction between shikimate-3-phosphate (S3P) and phosphoenolpyruvate (PEP) to form...; Region: EPSP_synthase; cd01556
936154003419	hinge; other site
936154003420	active site
936154003421	potential frameshift: common BLAST hit: gi|251782760|ref|YP_002997063.1| ribonuclease BN
936154003422	Virulence factor BrkB; Region: Virul_fac_BrkB; cl07918
936154003423	Ribonuclease BN family enzyme [Replication, recombination, and repair]; Region: Rbn; COG1295
936154003424	Methionine Aminopeptidase 1. E.C. 3.4.11.18. Also known as methionyl aminopeptidase and Peptidase M. Catalyzes release of N-terminal amino acids, preferentially methionine, from peptides and arylamides; Region: MetAP1; cd01086
936154003425	active site
936154003426	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
936154003427	DNA-binding site [nucleotide binding]; DNA binding site
936154003428	DRTGG domain; Region: DRTGG; pfam07085
936154003429	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
936154003430	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
936154003431	Transcriptional regulators [Transcription]; Region: FadR; COG2186
936154003432	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
936154003433	DNA-binding site [nucleotide binding]; DNA binding site
936154003434	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
936154003435	UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Region: murA; TIGR01072
936154003436	UDP-N-acetylglucosamine enolpyruvyl transferase catalyzes enolpyruvyl transfer as part of the first step in the biosynthesis of peptidoglycan, a component of the bacterial cell wall. The reaction is phosphoenolpyruvate + UDP-N-acetyl-D-glucosamine =...; Region: UdpNAET; cd01555
936154003437	hinge; other site
936154003438	active site
936154003439	S-adenosylmethionine synthetase; Validated; Region: PRK05250
936154003440	S-adenosylmethionine synthetase, N-terminal domain; Region: S-AdoMet_synt_N; pfam00438
936154003441	S-adenosylmethionine synthetase, central domain; Region: S-AdoMet_synt_M; pfam02772
936154003442	S-adenosylmethionine synthetase, C-terminal domain; Region: S-AdoMet_synt_C; pfam02773
936154003443	Biotin operon repressor [Transcription]; Region: BirA; COG1654
936154003444	bifunctional biotin--[acetyl-CoA-carboxylase] synthetase/biotin operon repressor; Provisional; Region: PRK11886
936154003445	Biotin/lipoate A/B protein ligase family; Region: BPL_LplA_LipB; pfam03099
936154003446	Biotin protein ligase C terminal domain; Region: BPL_C; pfam02237
936154003447	DNA polymerase III subunits gamma and tau; Validated; Region: PRK05563
936154003448	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
936154003449	Walker A motif; other site
936154003450	ATP binding site [chemical binding]; other site
936154003451	Walker B motif; other site
936154003452	arginine finger; other site
936154003453	DNA polymerase III subunits gamma and tau domain III; Region: DNA_pol3_gamma3; pfam12169
936154003454	GAF domain-containing protein [Signal transduction mechanisms]; Region: COG1956
936154003455	GAF domain; Region: GAF_2; pfam13185
936154003456	Protein of unknown function (DUF1294); Region: DUF1294; pfam06961
936154003457	Uridine kinase [Nucleotide transport and metabolism]; Region: Udk; COG0572
936154003458	Uridine monophosphate kinase (UMPK, EC 2.7.1.48), also known as uridine kinase or uridine-cytidine kinase (UCK), catalyzes the reversible phosphoryl transfer from ATP to uridine or cytidine to yield UMP or CMP. In the primidine nucleotide-salvage pathway; Region: UMPK; cd02023
936154003459	Sugar specificity; other site
936154003460	Pyrimidine base specificity; other site
936154003461	ATP-binding site [chemical binding]; other site
936154003462	Superfamily II DNA and RNA helicases [DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis]; Region: SrmB; COG0513
936154003463	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cl17251
936154003464	ATP binding site [chemical binding]; other site
936154003465	putative Mg++ binding site [ion binding]; other site
936154003466	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
936154003467	nucleotide binding region [chemical binding]; other site
936154003468	ATP-binding site [chemical binding]; other site
936154003469	Predicted xylanase/chitin deacetylase [Carbohydrate transport and metabolism]; Region: CDA1; COG0726
936154003470	Catalytic NodB homology domain of Streptococcus pneumoniae peptidoglycan deacetylase PgdA, Bacillus subtilis BsYjeA protein, and their bacterial homologs; Region: CE4_SpPgdA_BsYjeA_like; cd10947
936154003471	NodB motif; other site
936154003472	active site
936154003473	catalytic site [active]
936154003474	Zn binding site [ion binding]; other site
936154003475	NAD(P)+-dependent aldehyde dehydrogenase superfamily; Region: ALDH-SF; cl11961
936154003476	NAD(P) binding site [chemical binding]; other site
936154003477	catalytic residues [active]
936154003478	Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) [Carbohydrate transport and metabolism]; Region: PtsA; COG1080
936154003479	PEP-utilising enzyme, N-terminal; Region: PEP-utilisers_N; pfam05524
936154003480	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
936154003481	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
936154003482	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
936154003483	dimerization domain swap beta strand [polypeptide binding]; other site
936154003484	regulatory protein interface [polypeptide binding]; other site
936154003485	active site
936154003486	regulatory phosphorylation site [posttranslational modification]; other site
936154003487	NrdH-redoxin (NrdH) family; NrdH is a small monomeric protein with a conserved redox active CXXC motif within a TRX fold, characterized by a glutaredoxin (GRX)-like sequence and TRX-like activity profile. In vitro, it displays protein disulfide reductase...; Region: NrdH; cd02976
936154003488	catalytic residues [active]
936154003489	potential frameshift: common BLAST hit: gi|222153354|ref|YP_002562531.1| ribonucleotide-diphosphate reductase subunit alpha
936154003490	Ribonucleotide reductase N-terminal; Region: RNR_N; pfam08343
936154003491	Ribonucleotide reductase and Pyruvate formate lyase; Region: RNR_PFL; cl09939
936154003492	Ribonucleotide reductase, barrel domain; Region: Ribonuc_red_lgC; pfam02867
936154003493	ribonucleotide-diphosphate reductase subunit beta; Provisional; Region: nrdF2; PRK13966
936154003494	Ribonucleotide Reductase, R2/beta subunit, ferritin-like diiron-binding domain; Region: RNRR2; cd01049
936154003495	dimer interface [polypeptide binding]; other site
936154003496	putative radical transfer pathway; other site
936154003497	diiron center [ion binding]; other site
936154003498	tyrosyl radical; other site
936154003499	Chloride channel protein EriC [Inorganic ion transport and metabolism]; Region: EriC; COG0038
936154003500	Putative ClC chloride channel.  Clc proteins are putative halogen ion (Cl-, Br- and I-) transporters found in eubacteria. They belong to the ClC superfamily of halogen ion channels, which share a unique double-barreled architecture and voltage-dependent...; Region: ClC_like; cd01033
936154003501	putative ion selectivity filter; other site
936154003502	putative pore gating glutamate residue; other site
936154003503	alanyl-tRNA synthetase; Reviewed; Region: alaS; PRK00252
936154003504	Alanyl-tRNA synthetase (AlaRS) class II core catalytic domain. AlaRS is a homodimer. It is responsible for the attachment of alanine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: AlaRS_core; cd00673
936154003505	motif 1; other site
936154003506	active site
936154003507	motif 2; other site
936154003508	motif 3; other site
936154003509	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; smart00863
936154003510	DHHA1 domain; Region: DHHA1; pfam02272
936154003511	foldase protein PrsA; Reviewed; Region: prsA; PRK01326
936154003512	SurA N-terminal domain; Region: SurA_N; pfam09312
936154003513	PPIC-type PPIASE domain; Region: Rotamase_2; pfam13145
936154003514	Predicted O-methyltransferase [General function prediction only]; Region: COG4122
936154003515	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
936154003516	S-adenosylmethionine binding site [chemical binding]; other site
936154003517	Thiamine monophosphate synthase (TMP synthase)/TenI. TMP synthase catalyzes an important step in the thiamine biosynthesis pathway, the substitution of the pyrophosphate of 2-methyl-4-amino-5- hydroxymethylpyrimidine pyrophosphate by 4-methyl-5-; Region: TMP_TenI; cd00564
936154003518	thiamine phosphate binding site [chemical binding]; other site
936154003519	active site
936154003520	pyrophosphate binding site [ion binding]; other site
936154003521	4-methyl-5-beta-hydroxyethylthiazole (Thz) kinase catalyzes the phosphorylation of the hydroxylgroup of Thz. A reaction that allows cells to recycle Thz into the thiamine biosynthesis pathway, as an alternative to its synthesis from cysteine, tyrosine...; Region: THZ_kinase; cd01170
936154003522	multimerization interface [polypeptide binding]; other site
936154003523	substrate binding site [chemical binding]; other site
936154003524	ATP binding site [chemical binding]; other site
936154003525	4-amino-5-hydroxymethyl-2-methyl-pyrimidine phosphate kinase (HMPP-kinase) catalyzes two consecutive phosphorylation steps in the thiamine phosphate biosynthesis pathway, leading to the synthesis of vitamin B1. The first step is the phosphorylation of...; Region: HMPP_kinase; cd01169
936154003526	dimer interface [polypeptide binding]; other site
936154003527	substrate binding site [chemical binding]; other site
936154003528	ATP binding site [chemical binding]; other site
936154003529	Predicted phosphatases [General function prediction only]; Region: Gph; COG0546
936154003530	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
936154003531	motif II; other site
936154003532	oxalate/formate antiporter family transporter; Region: 2A0111; TIGR00890
936154003533	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
936154003534	putative substrate translocation pore; other site
936154003535	Predicted phosphatase/phosphohexomutase [General function prediction only]; Region: COG0637
936154003536	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
936154003537	motif II; other site
936154003538	Oligoendopeptidase F [Amino acid transport and metabolism]; Region: COG1164
936154003539	Peptidase family M3B Oligopeptidase F (PepF); Region: M3B_PepF_3; cd09608
936154003540	active site
936154003541	Zn binding site [ion binding]; other site
936154003542	Competence protein CoiA-like family; Region: CoiA; pfam06054
936154003543	Major Facilitator Superfamily; Region: MFS_1; pfam07690
936154003544	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
936154003545	putative substrate translocation pore; other site
936154003546	16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases [Translation, ribosomal structure and biogenesis]; Region: RsuA; COG1187
936154003547	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
936154003548	RNA binding surface [nucleotide binding]; other site
936154003549	Pseudouridine synthase, Escherichia coli RsuA like; Region: PseudoU_synth_RsuA; cd02553
936154003550	active site
936154003551	uracil binding [chemical binding]; other site
936154003552	6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase [Carbohydrate transport and metabolism]; Region: NagB; COG0363
936154003553	GlcN6P_deaminase: Glucosamine-6-phosphate (GlcN6P) deaminase subfamily; GlcN6P deaminase catalyzes the reversible conversion of GlcN6P to D-fructose-6-phosphate (Fru6P) and ammonium. The reaction is an aldo-keto isomerization coupled with an amination or...; Region: GlcN6P_deaminase; cd01399
936154003554	active site
936154003555	trimer interface [polypeptide binding]; other site
936154003556	allosteric site; other site
936154003557	active site lid [active]
936154003558	hexamer (dimer of trimers) interface [polypeptide binding]; other site
936154003559	S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Provisional; Region: queA; PRK00147
936154003560	Beta-lactamase enzyme family; Region: Beta-lactamase2; cl17872
936154003561	Superoxide dismutase [Inorganic ion transport and metabolism]; Region: SodA; COG0605
936154003562	Iron/manganese superoxide dismutases, alpha-hairpin domain; Region: Sod_Fe_N; pfam00081
936154003563	Iron/manganese superoxide dismutases, C-terminal domain; Region: Sod_Fe_C; pfam02777
936154003564	DNA polymerase III subunit delta; Reviewed; Region: holA; PRK05574
936154003565	DNA polymerase III, delta subunit; Region: DNA_pol3_delta; pfam06144
936154003566	Predicted membrane metal-binding protein [General function prediction only]; Region: ComEC; COG0658
936154003567	Competence protein; Region: Competence; pfam03772
936154003568	Predicted hydrolase (metallo-beta-lactamase superfamily) [General function prediction only]; Region: ComEC; COG2333
936154003569	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
936154003570	SLBB domain; Region: SLBB; pfam10531
936154003571	comEA protein; Region: comE; TIGR01259
936154003572	RelA- and SpoT-like ppGpp Synthetases and Hydrolases, catalytic domain; Region: Rel-Spo_like; cl11966
936154003573	1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid metabolism]; Region: PlsC; COG0204
936154003574	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989
936154003575	putative acyl-acceptor binding pocket; other site
936154003576	Predicted O-methyltransferase [General function prediction only]; Region: COG4123
936154003577	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
936154003578	S-adenosylmethionine binding site [chemical binding]; other site
936154003579	K+ potassium transporter; Region: K_trans; cl15781
936154003580	helicase 45; Provisional; Region: PTZ00424
936154003581	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
936154003582	ATP binding site [chemical binding]; other site
936154003583	Mg++ binding site [ion binding]; other site
936154003584	motif III; other site
936154003585	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
936154003586	nucleotide binding region [chemical binding]; other site
936154003587	ATP-binding site [chemical binding]; other site
936154003588	Cof subfamily of IIB subfamily of haloacid dehalogenase superfamily; Region: Cof-subfamily; TIGR00099
936154003589	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
936154003590	active site
936154003591	motif I; other site
936154003592	motif II; other site
936154003593	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cl17170
936154003594	G2 box; other site
936154003595	Switch I region; other site
936154003596	G3 box; other site
936154003597	Switch II region; other site
936154003598	GTP/Mg2+ binding site [chemical binding]; other site
936154003599	G4 box; other site
936154003600	G5 box; other site
936154003601	RF3_II: this subfamily represents the domain II of bacterial Release Factor 3 (RF3). Termination of protein synthesis by the ribosome requires two release factor (RF) classes. The class II RF3 is a GTPase that removes class I RFs (RF1 or RF2) from the...; Region: RF3_II; cd03689
936154003602	Integral membrane protein (intg_mem_TP0381); Region: Intg_mem_TP0381; pfam09529
936154003603	UDP-N-acetylmuramyl pentapeptide synthase [Cell envelope biogenesis, outer membrane]; Region: MurF; COG0770
936154003604	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
936154003605	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
936154003606	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
936154003607	ECF-type riboflavin transporter, S component; Region: ECF-ribofla_trS; pfam07155
936154003608	Protein of unknown function (DUF3816); Region: DUF3816; pfam12822
936154003609	D-alanyl-alanine synthetase A; Reviewed; Region: ddl; PRK01966
936154003610	D-ala D-ala ligase N-terminus; Region: Dala_Dala_lig_N; pfam01820
936154003611	D-ala D-ala ligase C-terminus; Region: Dala_Dala_lig_C; pfam07478
936154003612	recombination protein RecR; Reviewed; Region: recR; PRK00076
936154003613	RecR protein; Region: RecR; pfam02132
936154003614	TOPRIM_recR: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in Escherichia coli RecR.  RecR participates in the RecFOR pathway of homologous recombinational repair in prokaryotes. This pathway provides a...; Region: TOPRIM_recR; cd01025
936154003615	putative active site [active]
936154003616	putative metal-binding site [ion binding]; other site
936154003617	tetramer interface [polypeptide binding]; other site
936154003618	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
936154003619	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
936154003620	Cell division protein FtsI/penicillin-binding protein 2 [Cell envelope biogenesis, outer membrane]; Region: FtsI; COG0768
936154003621	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
936154003622	Formate/nitrite family of transporters [Inorganic ion transport and metabolism]; Region: FocA; COG2116
936154003623	Predicted small molecule binding protein (contains 3H domain) [General function prediction only]; Region: COG1827
936154003624	HTH domain; Region: HTH_11; pfam08279
936154003625	3H domain; Region: 3H; pfam02829
936154003626	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
936154003627	catalytic core [active]
936154003628	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
936154003629	dihydroorotate dehydrogenase (subfamily 1) family protein; Region: pyrD_sub1_fam; TIGR01037
936154003630	Dihydroorotate dehydrogenase (DHOD) class 1A FMN-binding domain. DHOD catalyzes the oxidation of (S)-dihydroorotate to orotate. This is the fourth step and the only redox reaction in the de novo biosynthesis of UMP, the precursor of all pyrimidine...; Region: DHOD_1A_like; cd04741
936154003631	active site
936154003632	FMN binding site [chemical binding]; other site
936154003633	substrate binding site [chemical binding]; other site
936154003634	catalytic residues [active]
936154003635	homodimer interface [polypeptide binding]; other site
936154003636	heavy metal-(Cd/Co/Hg/Pb/Zn)-translocating P-type ATPase; Region: ATPase-IB2_Cd; TIGR01512
936154003637	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
936154003638	Soluble P-type ATPase [General function prediction only]; Region: COG4087
936154003639	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
936154003640	IHF dimer interface [polypeptide binding]; other site
936154003641	IHF - DNA interface [nucleotide binding]; other site
936154003642	Uncharacterized protein conserved in bacteria (DUF2140); Region: DUF2140; cl11548
936154003643	Members of the SGNH-hydrolase superfamily, a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely...; Region: SGNH_hydrolase_YpmR_like; cd04506
936154003644	active site
936154003645	catalytic triad [active]
936154003646	oxyanion hole [active]
936154003647	EDD domain protein, DegV family; Region: DegV; TIGR00762
936154003648	Uncharacterized protein, DegV family COG1307; Region: DegV; pfam02645
936154003649	ATPase involved in DNA repair [DNA replication, recombination, and repair]; Region: RecN; COG0497
936154003650	ATP-binding cassette domain of RecN; Region: ABC_RecN; cd03241
936154003651	Walker A/P-loop; other site
936154003652	ATP binding site [chemical binding]; other site
936154003653	Q-loop/lid; other site
936154003654	ATP-binding cassette domain of RecN; Region: ABC_RecN; cd03241
936154003655	ABC transporter signature motif; other site
936154003656	Walker B; other site
936154003657	D-loop; other site
936154003658	H-loop/switch region; other site
936154003659	Arginine repressor [Transcription]; Region: ArgR; COG1438
936154003660	Arginine repressor, DNA binding domain; Region: Arg_repressor; pfam01316
936154003661	Arginine repressor, C-terminal domain; Region: Arg_repressor_C; pfam02863
936154003662	Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; Region: IspA; COG0142
936154003663	Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685
936154003664	substrate binding pocket [chemical binding]; other site
936154003665	chain length determination region; other site
936154003666	substrate-Mg2+ binding site; other site
936154003667	catalytic residues [active]
936154003668	aspartate-rich region 1; other site
936154003669	active site lid residues [active]
936154003670	aspartate-rich region 2; other site
936154003671	exodeoxyribonuclease VII small subunit; Provisional; Region: PRK00977
936154003672	exodeoxyribonuclease VII large subunit; Reviewed; Region: xseA; PRK00286
936154003673	ExoVII_LU_OBF: A subfamily of OB folds corresponding to the N-terminal OB-fold domain of Escherichia coli exodeoxyribonuclease VII (ExoVII) large subunit. E. coli ExoVII is composed of two non-identical subunits. E. coli ExoVII is a...; Region: ExoVII_LU_OBF; cd04489
936154003674	generic binding surface II; other site
936154003675	generic binding surface I; other site
936154003676	B.subtilis YXKO protein of unknown function and related proteins. Based on the conservation of the ATP binding site, the substrate binding site and the Mg2+binding site and structural homology this group is a member of the ribokinase-like superfamily; Region: YXKO-related; cd01171
936154003677	putative substrate binding site [chemical binding]; other site
936154003678	putative ATP binding site [chemical binding]; other site
936154003679	bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase; Provisional; Region: PRK14179
936154003680	Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain; Region: THF_DHG_CYH; pfam00763
936154003681	NADP binding domain of methylene-tetrahydrofolate dehydrogenase/cyclohydrolase; Region: NAD_bind_m-THF_DH_Cyclohyd; cd01080
936154003682	homodimer interface [polypeptide binding]; other site
936154003683	NADP binding site [chemical binding]; other site
936154003684	substrate binding site [chemical binding]; other site
936154003685	Fe2+ transport system protein B [Inorganic ion transport and metabolism]; Region: FeoB; COG0370
936154003686	Nucleoside recognition; Region: Gate; pfam07670
936154003687	Ferrous iron transport protein B C terminus; Region: FeoB_C; pfam07664
936154003688	Nucleoside recognition; Region: Gate; pfam07670
936154003689	This entry represents the core domain of the ferrous iron (Fe2+) transport protein FeoA found in bacteria; Region: FeoA; smart00899
936154003690	Fe2+ transport system protein A [Inorganic ion transport and metabolism]; Region: FeoA; COG1918
936154003691	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
936154003692	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
936154003693	Walker A/P-loop; other site
936154003694	ATP binding site [chemical binding]; other site
936154003695	Q-loop/lid; other site
936154003696	ABC transporter signature motif; other site
936154003697	Walker B; other site
936154003698	D-loop; other site
936154003699	H-loop/switch region; other site
936154003700	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
936154003701	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
936154003702	dimer interface [polypeptide binding]; other site
936154003703	conserved gate region; other site
936154003704	putative PBP binding loops; other site
936154003705	ABC-ATPase subunit interface; other site
936154003706	Protein of unknown function (DUF1797); Region: DUF1797; cl11550
936154003707	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
936154003708	ATPases associated with a variety of cellular activities; Region: AAA; smart00382
936154003709	Walker A motif; other site
936154003710	ATP binding site [chemical binding]; other site
936154003711	Walker B motif; other site
936154003712	arginine finger; other site
936154003713	UvrB/uvrC motif; Region: UVR; pfam02151
936154003714	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
936154003715	ATPases associated with a variety of cellular activities; Region: AAA; smart00382
936154003716	Walker A motif; other site
936154003717	ATP binding site [chemical binding]; other site
936154003718	Walker B motif; other site
936154003719	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431
936154003720	Contains a crystal structure of the Nudix hydrolase from Enterococcus faecalis, which has an unknown function. In general, members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes...; Region: Nudix_Hydrolase_25; cd04684
936154003721	nudix motif; other site
936154003722	Domain of unknown function (DUF1827); Region: DUF1827; pfam08860
936154003723	isoleucyl-tRNA synthetase; Provisional; Region: ileS; PRK13804
936154003724	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
936154003725	active site
936154003726	HIGH motif; other site
936154003727	nucleotide binding site [chemical binding]; other site
936154003728	catalytic core domain of isoleucyl-tRNA synthetases; Region: IleRS_core; cd00818
936154003729	active site
936154003730	KMSKS motif; other site
936154003731	Anticodon-binding domain of bacterial and eukaryotic mitochondrial isoleucyl tRNA synthetases; Region: Anticodon_Ia_Ile_BEm; cd07960
936154003732	tRNA binding surface [nucleotide binding]; other site
936154003733	anticodon binding site; other site
936154003734	DivIVA protein; Region: DivIVA; pfam05103
936154003735	DivIVA domain; Region: DivI1A_domain; TIGR03544
936154003736	Uncharacterized conserved protein, contains S4-like domain [Function unknown]; Region: COG2302
936154003737	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
936154003738	RNA binding surface [nucleotide binding]; other site
936154003739	YGGT family; Region: YGGT; pfam02325
936154003740	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1799
936154003741	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes, YBL036c-like proteins; Region: PLPDE_III_YBL036c_like; cd00635
936154003742	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
936154003743	catalytic residue [active]
936154003744	cell division protein FtsZ; Validated; Region: PRK09330
936154003745	FtsZ is a GTPase that is similar to the eukaryotic tubulins and is essential for cell division in prokaryotes.  FtsZ is capable of polymerizing in a GTP-driven process into structures similar to those formed by tubulin. FtsZ forms a ring-shaped septum at...; Region: FtsZ_type1; cd02201
936154003746	nucleotide binding site [chemical binding]; other site
936154003747	SulA interaction site; other site
936154003748	Cell division ATPase FtsA [Cell division and chromosome partitioning]; Region: ftsA; COG0849
936154003749	Cell division protein FtsA; Region: FtsA; smart00842
936154003750	Cell division protein FtsA; Region: FtsA; pfam14450
936154003751	Domain of unknown function (DUF3484); Region: DUF3484; pfam11983
936154003752	POTRA domain, FtsQ-type; Region: POTRA_1; pfam08478
936154003753	Cell division protein FtsQ; Region: FtsQ; pfam03799
936154003754	undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase; Provisional; Region: murG; PRK00726
936154003755	MurG is an N-acetylglucosaminyltransferase, the last enzyme involved in the intracellular phase of peptidoglycan biosynthesis. It transfers N-acetyl-D-glucosamine (GlcNAc) from UDP-GlcNAc to the C4 hydroxyl of a lipid-linked N-acetylmuramoyl pentapeptide...; Region: GT1_MurG; cd03785
936154003756	active site
936154003757	homodimer interface [polypeptide binding]; other site
936154003758	UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase; Provisional; Region: murD; PRK02472
936154003759	Alanine dehydrogenase/PNT, C-terminal domain; Region: AlaDh_PNT_C; smart01002
936154003760	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
936154003761	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
936154003762	Protein of unknown function (DUF3165); Region: DUF3165; pfam11364
936154003763	Predicted membrane GTPase involved in stress response [Signal transduction mechanisms]; Region: TypA; COG1217
936154003764	Tyrosine phosphorylated protein A (TypA)/BipA family belongs to ribosome-binding GTPases; Region: TypA_BipA; cd01891
936154003765	G1 box; other site
936154003766	putative GEF interaction site [polypeptide binding]; other site
936154003767	GTP/Mg2+ binding site [chemical binding]; other site
936154003768	Switch I region; other site
936154003769	G2 box; other site
936154003770	G3 box; other site
936154003771	Switch II region; other site
936154003772	G4 box; other site
936154003773	G5 box; other site
936154003774	BipA_TypA_II: domain II of BipA (also called TypA) having homology to domain II of the elongation factors (EFs) EF-G and EF-Tu.  BipA is a highly conserved protein with global regulatory properties in Escherichia coli. BipA is phosphorylated on a...; Region: BipA_TypA_II; cd03691
936154003775	BipA_TypA_C: a C-terminal portion of BipA or TypA having homology to the C terminal domains of the elongation factors EF-G and EF-2. A member of the ribosome binding GTPase superfamily, BipA is widely distributed in bacteria and plants.  BipA is a highly...; Region: BipA_TypA_C; cd03710
936154003776	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
936154003777	active site residue [active]
936154003778	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
936154003779	nucleotide binding site [chemical binding]; other site
936154003780	Ferritin-like domain; Region: Ferritin; pfam00210
936154003781	DPS protein, ferritin-like diiron-binding domain; Region: DPS; cd01043
936154003782	dimerization interface [polypeptide binding]; other site
936154003783	DPS ferroxidase diiron center [ion binding]; other site
936154003784	ion pore; other site
936154003785	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
936154003786	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
936154003787	ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Region: ABCC_Glucan_exporter_like; cd03254
936154003788	Walker A/P-loop; other site
936154003789	ATP binding site [chemical binding]; other site
936154003790	Q-loop/lid; other site
936154003791	ABC transporter signature motif; other site
936154003792	Walker B; other site
936154003793	D-loop; other site
936154003794	H-loop/switch region; other site
936154003795	thiol reductant ABC exporter, CydD subunit; Region: CydD; TIGR02857
936154003796	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
936154003797	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
936154003798	Walker A/P-loop; other site
936154003799	ATP binding site [chemical binding]; other site
936154003800	Q-loop/lid; other site
936154003801	ABC transporter signature motif; other site
936154003802	Walker B; other site
936154003803	D-loop; other site
936154003804	VanZ like family; Region: VanZ; pfam04892
936154003805	ribosomal RNA large subunit methyltransferase N; Provisional; Region: PRK14455
936154003806	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
936154003807	FeS/SAM binding site; other site
936154003808	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4470
936154003809	Escherichia coli UshA-like family, N-terminal metallophosphatase domain; Region: MPP_UshA_N_like; cd00845
936154003810	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
936154003811	active site
936154003812	metal binding site [ion binding]; metal-binding site
936154003813	5'-nucleotidase, C-terminal domain; Region: 5_nucleotid_C; pfam02872
936154003814	D-ribose transporter subunit RbsB; Provisional; Region: PRK10653
936154003815	Periplasmic sugar-binding domain of the thermophilic Thermoanaerobacter tengcongensis ribose binding protein (ttRBP) and its mesophilic homologs; Region: PBP1_ribose_binding; cd06323
936154003816	ligand binding site [chemical binding]; other site
936154003817	dimerization interface [polypeptide binding]; other site
936154003818	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
936154003819	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
936154003820	TM-ABC transporter signature motif; other site
936154003821	ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; Region: MglA; COG1129
936154003822	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
936154003823	Walker A/P-loop; other site
936154003824	ATP binding site [chemical binding]; other site
936154003825	Q-loop/lid; other site
936154003826	ABC transporter signature motif; other site
936154003827	Walker B; other site
936154003828	D-loop; other site
936154003829	H-loop/switch region; other site
936154003830	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
936154003831	D-ribose pyranase; Provisional; Region: PRK11797
936154003832	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
936154003833	Ribokinase catalyses the phosphorylation of ribose to ribose-5-phosphate using ATP. This reaction is the first step in the ribose metabolism. It traps ribose within the cell after uptake and also prepares the sugar for use in the synthesis of nucleotides...; Region: ribokinase; cd01174
936154003834	substrate binding site [chemical binding]; other site
936154003835	dimer interface [polypeptide binding]; other site
936154003836	ATP binding site [chemical binding]; other site
936154003837	potential frameshift: common BLAST hit: gi|251782943|ref|YP_002997246.1|  ribose transport operon repressor
936154003838	Transcriptional regulators [Transcription]; Region: PurR; COG1609
936154003839	Type 1 periplasmic binding fold superfamily; Region: Periplasmic_Binding_Protein_Type_1; cl10011
936154003840	Transcriptional regulators [Transcription]; Region: PurR; COG1609
936154003841	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
936154003842	DNA binding site [nucleotide binding]
936154003843	domain linker motif; other site
936154003844	Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267
936154003845	dimerization interface [polypeptide binding]; other site
936154003846	Predicted secreted protein containing a PDZ domain [Signal transduction mechanisms]; Region: SdrC; COG3480
936154003847	PDZ domain, also called DHR (Dlg homologous region) or GLGF (after a conserved sequence motif). Many PDZ domains bind C-terminal polypeptides, though binding to internal (non-C-terminal) polypeptides and even to lipids has been demonstrated; Region: PDZ; cl00117
936154003848	protein binding site [polypeptide binding]; other site
936154003849	phosphopantetheine adenylyltransferase; Provisional; Region: coaD; PRK00168
936154003850	Phosphopantetheine adenylyltransferase; Region: PPAT; cd02163
936154003851	active site
936154003852	(T/H)XGH motif; other site
936154003853	Conserved hypothetical protein 95; Region: Cons_hypoth95; pfam03602
936154003854	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
936154003855	S-adenosylmethionine binding site [chemical binding]; other site
936154003856	Asparagine synthetase (aspartate-ammonia ligase) (AsnA) catalyses the conversion of L-aspartate to L-asparagine in the presence of ATP and ammonia.  AsnA is a homodimeric enzyme which is structurally similiar to the catalytic core domain of class II...; Region: AsnA; cd00645
936154003857	dimer interface [polypeptide binding]; other site
936154003858	active site
936154003859	carbamate kinase; Reviewed; Region: PRK12686
936154003860	AAK_CK: Carbamate kinase (CK) catalyzes both the ATP-phosphorylation of carbamate and carbamoyl phosphate (CP) utilization with the production of ATP from ADP and CP. Both CK (this CD) and nonhomologous CP synthetase synthesize carbamoyl phosphate, an...; Region: AAK_CK; cd04235
936154003861	putative substrate binding site [chemical binding]; other site
936154003862	nucleotide binding site [chemical binding]; other site
936154003863	nucleotide binding site [chemical binding]; other site
936154003864	homodimer interface [polypeptide binding]; other site
936154003865	hypothetical protein; Provisional; Region: PRK07205
936154003866	M20 Peptidase Xaa-His dipeptidase (PepV) degrades hydrophobic dipeptides; Region: M20_PepV; cd03888
936154003867	active site
936154003868	metal binding site [ion binding]; metal-binding site
936154003869	Predicted membrane protein [Function unknown]; Region: COG1288
936154003870	C4-dicarboxylate anaerobic carrier; Region: DcuC; pfam03606
936154003871	ornithine carbamoyltransferase; Validated; Region: PRK02102
936154003872	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
936154003873	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
936154003874	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
936154003875	Coenzyme A binding pocket [chemical binding]; other site
936154003876	arginine deiminase; Provisional; Region: PRK01388
936154003877	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
936154003878	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
936154003879	ligand binding site [chemical binding]; other site
936154003880	flexible hinge region; other site
936154003881	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cd00092
936154003882	putative switch regulator; other site
936154003883	non-specific DNA interactions [nucleotide binding]; other site
936154003884	DNA binding site [nucleotide binding]
936154003885	sequence specific DNA binding site [nucleotide binding]; other site
936154003886	putative cAMP binding site [chemical binding]; other site
936154003887	Arginine repressor [Transcription]; Region: ArgR; COG1438
936154003888	Arginine repressor, DNA binding domain; Region: Arg_repressor; pfam01316
936154003889	Arginine repressor, C-terminal domain; Region: Arg_repressor_C; pfam02863
936154003890	Solo B3/4 domain (OB-fold DNA/RNA-binding) of Phe-aaRS-beta [General function prediction only]; Region: COG3382
936154003891	B3/4 domain; Region: B3_4; pfam03483
936154003892	Protein of unknown function (DUF419); Region: DUF419; pfam04237
936154003893	CorA-like Mg2+ transporter protein; Region: CorA; pfam01544
936154003894	uncharacterized bacterial subfamily of the Escherichia coli CorA-Salmonella typhimurium ZntB family; Region: EcCorA_ZntB-like_u2; cd12827
936154003895	Cl binding site [ion binding]; other site
936154003896	oligomer interface [polypeptide binding]; other site
936154003897	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
936154003898	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
936154003899	Eco47II restriction endonuclease; Region: RE_Eco47II; pfam09553
936154003900	putative transposase OrfB; Reviewed; Region: PHA02517
936154003901	HTH-like domain; Region: HTH_21; pfam13276
936154003902	Integrase core domain; Region: rve; pfam00665
936154003903	Integrase core domain; Region: rve_3; pfam13683
936154003904	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cl00075
936154003905	Glycosaminoglycan (GAG) polysaccharide lyase family. This family consists of a group of secreted bacterial lyase enzymes capable of acting on glycosaminoglycans, such as hyaluronan and chondroitin, in the extracellular matrix of host tissues; Region: GAG_Lyase; cd01083
936154003906	substrate binding site [chemical binding]; other site
936154003907	catalytic residues [active]
936154003908	Transcriptional regulators [Transcription]; Region: PurR; COG1609
936154003909	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
936154003910	DNA binding site [nucleotide binding]
936154003911	domain linker motif; other site
936154003912	Ligand-binding domain of DNA transcription repressor RegR and other putative regulators such as KdgR and EndR; Region: PBP1_RegR_EndR_KdgR_like; cd06283
936154003913	putative dimerization interface [polypeptide binding]; other site
936154003914	putative ligand binding site [chemical binding]; other site
936154003915	Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IID [Carbohydrate transport and metabolism]; Region: ManZ; COG3716
936154003916	Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIC [Carbohydrate transport and metabolism]; Region: ManY; COG3715
936154003917	PTS_IIB, PTS system, Mannose/sorbose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_man; cd00001
936154003918	active site
936154003919	phosphorylation site [posttranslational modification]
936154003920	Glycosyl Hydrolase Family 88; Region: Glyco_hydro_88; pfam07470
936154003921	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cd00006
936154003922	active pocket/dimerization site; other site
936154003923	active site
936154003924	phosphorylation site [posttranslational modification]
936154003925	gluconate 5-dehydrogenase; Provisional; Region: PRK07097
936154003926	gluconate 5-dehydrogenase (Ga5DH)-like, classical (c) SDRs; Region: Ga5DH-like_SDR_c; cd05347
936154003927	NADP binding site [chemical binding]; other site
936154003928	homodimer interface [polypeptide binding]; other site
936154003929	active site
936154003930	2-keto-3-deoxygluconate kinase (KdgK) phosphorylates 2-keto-3-deoxygluconate (KDG) to form 2-keto-3-deoxy-6-phosphogluconate (KDGP). KDG is the common intermediate product, that allows organisms to channel D-glucuronate and/or D-galacturinate into the...; Region: KdgK; cd01166
936154003931	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
936154003932	substrate binding site [chemical binding]; other site
936154003933	ATP binding site [chemical binding]; other site
936154003934	2-keto-3-deoxy-6-phosphogluconate aldolase [Carbohydrate transport and metabolism]; Region: Eda; COG0800
936154003935	KDPG and KHG aldolase; Region: KDPG_aldolase; cd00452
936154003936	active site
936154003937	intersubunit interface [polypeptide binding]; other site
936154003938	catalytic residue [active]
936154003939	GBS Bsp-like repeat; Region: GBS_Bsp-like; pfam08481
936154003940	GBS Bsp-like repeat; Region: GBS_Bsp-like; pfam08481
936154003941	GBS Bsp-like repeat; Region: GBS_Bsp-like; pfam08481
936154003942	GBS Bsp-like repeat; Region: GBS_Bsp-like; pfam08481
936154003943	GBS Bsp-like repeat; Region: GBS_Bsp-like; pfam08481
936154003944	GBS Bsp-like repeat; Region: GBS_Bsp-like; pfam08481
936154003945	Peptidase family C39 mostly contains bacteriocin-processing endopeptidases from bacteria. The cysteine peptidases in family C39 cleave the "double-glycine" leader peptides from the precursors of various bacteriocins (mostly non-lantibiotic); Region: Peptidase_C39_like; cl00296
936154003946	putative active site [active]
936154003947	valyl-tRNA synthetase; Reviewed; Region: valS; PRK05729
936154003948	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
936154003949	active site
936154003950	HIGH motif; other site
936154003951	nucleotide binding site [chemical binding]; other site
936154003952	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
936154003953	catalytic core domain of valyl-tRNA synthetases; Region: ValRS_core; cd00817
936154003954	active site
936154003955	KMSKS motif; other site
936154003956	Anticodon-binding domain of valyl tRNA synthetases; Region: Anticodon_Ia_Val; cd07962
936154003957	tRNA binding surface [nucleotide binding]; other site
936154003958	anticodon binding site; other site
936154003959	Valyl tRNA synthetase tRNA binding arm; Region: Val_tRNA-synt_C; pfam10458
936154003960	Protein of unknown function (DUF1349); Region: DUF1349; pfam07081
936154003961	Maltose O-acetyltransferase (MAT) and Galactoside O-acetyltransferase (GAT): MAT and GAT catalyze the CoA-dependent acetylation of the 6-hydroxyl group of their respective sugar substrates. MAT acetylates maltose and glucose exclusively at the C6...; Region: LbH_MAT_GAT; cd03357
936154003962	trimer interface [polypeptide binding]; other site
936154003963	Acetyltransferase (isoleucine patch superfamily) [General function prediction only]; Region: WbbJ; COG0110
936154003964	active site
936154003965	substrate binding site [chemical binding]; other site
936154003966	CoA binding site [chemical binding]; other site
936154003967	Domain of unknown function (DUF1912); Region: DUF1912; pfam08930
936154003968	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
936154003969	MarR family; Region: MarR; pfam01047
936154003970	Na+-driven multidrug efflux pump [Defense mechanisms]; Region: NorM; COG0534
936154003971	Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Streptococcus aureus MepA; Region: MATE_MepA_like; cd13143
936154003972	Predicted Zn-dependent hydrolases of the beta-lactamase fold [General function prediction only]; Region: COG2220
936154003973	Beta-lactamase superfamily domain; Region: Lactamase_B_2; pfam12706
936154003974	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
936154003975	Major Facilitator Superfamily; Region: MFS_1; pfam07690
936154003976	putative substrate translocation pore; other site
936154003977	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
936154003978	Radical SAM superfamily; Region: Radical_SAM; pfam04055
936154003979	FeS/SAM binding site; other site
936154003980	radical SAM additional 4Fe4S-binding SPASM domain; Region: rSAM_more_4Fe4S; TIGR04085
936154003981	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
936154003982	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
936154003983	non-specific DNA binding site [nucleotide binding]; other site
936154003984	salt bridge; other site
936154003985	sequence-specific DNA binding site [nucleotide binding]; other site
936154003986	transcriptional activator, Rgg/GadR/MutR family, C-terminal domain; Region: RGG_Cterm; TIGR01716
936154003987	Transposase; Region: HTH_Tnp_1; pfam01527
936154003988	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
936154003989	putative transposase OrfB; Reviewed; Region: PHA02517
936154003990	HTH-like domain; Region: HTH_21; pfam13276
936154003991	Integrase core domain; Region: rve; pfam00665
936154003992	Integrase core domain; Region: rve_3; pfam13683
936154003993	Predicted epimerase, PhzC/PhzF homolog [General function prediction only]; Region: COG0384
936154003994	manganese transport protein MntH; Reviewed; Region: PRK00701
936154003995	Natural resistance-associated macrophage protein; Region: Nramp; pfam01566
936154003996	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
936154003997	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
936154003998	Walker A/P-loop; other site
936154003999	ATP binding site [chemical binding]; other site
936154004000	Q-loop/lid; other site
936154004001	ABC transporter signature motif; other site
936154004002	Walker B; other site
936154004003	D-loop; other site
936154004004	H-loop/switch region; other site
936154004005	ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms]; Region: SalY; COG0577
936154004006	FtsX-like permease family; Region: FtsX; pfam02687
936154004007	Predicted glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]; Region: ECM4; COG0435
936154004008	Glutathione S-transferase, N-terminal domain; Region: GST_N_2; pfam13409
936154004009	C-terminal, alpha helical domain of Class Omega-like Glutathione S-transferases; Region: GST_C_Omega_like; cd03190
936154004010	putative dimer interface [polypeptide binding]; other site
936154004011	N-terminal domain interface [polypeptide binding]; other site
936154004012	putative substrate binding pocket (H-site) [chemical binding]; other site
936154004013	ABC-type uncharacterized transport system, ATPase component [General function prediction only]; Region: COG4152
936154004014	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
936154004015	Walker A/P-loop; other site
936154004016	ATP binding site [chemical binding]; other site
936154004017	Q-loop/lid; other site
936154004018	ABC transporter signature motif; other site
936154004019	Walker B; other site
936154004020	D-loop; other site
936154004021	H-loop/switch region; other site
936154004022	Domain of unknown function (DUF4162); Region: DUF4162; pfam13732
936154004023	ABC-type Na+ efflux pump, permease component [Energy production and conversion / Inorganic ion transport and metabolism]; Region: NatB; COG1668
936154004024	SNARE associated Golgi protein; Region: SNARE_assoc; cl00429
936154004025	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
936154004026	Membrane transport protein; Region: Mem_trans; cl09117
936154004027	Old yellow enzyme (OYE)-related FMN binding domain, group 4.  Each monomer of OYE contains FMN as a non-covalently bound cofactor, uses NADPH as a reducing agent with oxygens, quinones, and alpha,beta-unsaturated aldehydes and ketones, and can act as...; Region: OYE_like_4_FMN; cd04735
936154004028	NADH:flavin oxidoreductases, Old Yellow Enzyme family [Energy production and conversion]; Region: NemA; COG1902
936154004029	putative active site [active]
936154004030	putative FMN binding site [chemical binding]; other site
936154004031	putative substrate binding site [chemical binding]; other site
936154004032	putative catalytic residue [active]
936154004033	FMN-binding domain; Region: FMN_bind; pfam04205
936154004034	flavocytochrome c; Region: flavo_cyto_c; TIGR01813
936154004035	3-dehydroquinate dehydratase [Amino acid transport and metabolism]; Region: AroD; COG0710
936154004036	Type I 3-dehydroquinase, (3-dehydroquinate dehydratase or DHQase); Region: DHQase_I; cd00502
936154004037	active site
936154004038	catalytic residue [active]
936154004039	dimer interface [polypeptide binding]; other site
936154004040	shikimate 5-dehydrogenase; Provisional; Region: PRK12548
936154004041	Shikimate dehydrogenase substrate binding domain; Region: Shikimate_dh_N; pfam08501
936154004042	NAD(P) binding domain of Shikimate dehydrogenase; Region: NAD_bind_Shikimate_DH; cd01065
936154004043	shikimate binding site; other site
936154004044	NAD(P) binding site [chemical binding]; other site
936154004045	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
936154004046	putative substrate translocation pore; other site
936154004047	Major Facilitator Superfamily; Region: MFS_1; pfam07690
936154004048	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
936154004049	Major Facilitator Superfamily; Region: MFS_1; pfam07690
936154004050	putative substrate translocation pore; other site
936154004051	3-ketoacyl-(acyl-carrier-protein) reductase; Provisional; Region: fabG; PRK07231
936154004052	classical (c) SDRs; Region: SDR_c; cd05233
936154004053	NAD(P) binding site [chemical binding]; other site
936154004054	active site
936154004055	Xylose isomerase-like TIM barrel; Region: AP_endonuc_2; pfam01261
936154004056	Transcriptional regulator [Transcription]; Region: LysR; COG0583
936154004057	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
936154004058	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
936154004059	dimerization interface [polypeptide binding]; other site
936154004060	Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain [Signal transduction mechanisms]; Region: COG4753
936154004061	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
936154004062	active site
936154004063	phosphorylation site [posttranslational modification]
936154004064	intermolecular recognition site; other site
936154004065	dimerization interface [polypeptide binding]; other site
936154004066	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
936154004067	Predicted signal transduction protein with a C-terminal ATPase domain [Signal transduction mechanisms]; Region: COG2972
936154004068	Histidine kinase; Region: His_kinase; pfam06580
936154004069	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
936154004070	ATP binding site [chemical binding]; other site
936154004071	Mg2+ binding site [ion binding]; other site
936154004072	G-X-G motif; other site
936154004073	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
936154004074	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
936154004075	Domain of unknown function (DUF3502); Region: DUF3502; pfam12010
936154004076	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
936154004077	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
936154004078	dimer interface [polypeptide binding]; other site
936154004079	ABC-ATPase subunit interface; other site
936154004080	ABC-type polysaccharide transport system, permease component [Carbohydrate transport and metabolism]; Region: LplB; COG4209
936154004081	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
936154004082	dimer interface [polypeptide binding]; other site
936154004083	conserved gate region; other site
936154004084	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cl00427
936154004085	ABC-ATPase subunit interface; other site
936154004086	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
936154004087	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
936154004088	nucleotide binding site [chemical binding]; other site
936154004089	Putative alpha-1,2-mannosidase [Carbohydrate transport and metabolism]; Region: COG3537
936154004090	Glycosyl hydrolase family 92; Region: Glyco_hydro_92; pfam07971
936154004091	beta-N-acetylglucosaminidase; Region: NAGidase; pfam07555
936154004092	beta-N-acetylglucosaminidase; Region: NAGidase; pfam07555
936154004093	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
936154004094	DNA-binding site [nucleotide binding]; DNA binding site
936154004095	Transcriptional regulators [Transcription]; Region: PurR; COG1609
936154004096	Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267
936154004097	dimerization interface [polypeptide binding]; other site
936154004098	ligand binding site [chemical binding]; other site
936154004099	Uncharacterized conserved protein [Function unknown]; Region: COG3538
936154004100	Protein of unknown function (DUF1237); Region: DUF1237; pfam06824
936154004101	Alpha-mannosidase [Carbohydrate transport and metabolism]; Region: AMS1; COG0383
936154004102	N-terminal catalytic domain of SPGH38, a putative alpha-mannosidase of Streptococcus pyogenes, and its prokaryotic homologs; glycoside hydrolase family 38 (GH38); Region: GH38N_AMII_SpGH38_like; cd10814
936154004103	active site
936154004104	metal binding site [ion binding]; metal-binding site
936154004105	homodimer interface [polypeptide binding]; other site
936154004106	catalytic site [active]
936154004107	Alpha-mannosidase [Carbohydrate transport and metabolism]; Region: AMS1; COG0383
936154004108	Alpha mannosidase, middle domain; Region: Alpha-mann_mid; smart00872
936154004109	SGNH_hydrolase, or GDSL_hydrolase, is a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely...; Region: SGNH_hydrolase; cl01053
936154004110	active site
936154004111	catalytic triad [active]
936154004112	oxyanion hole [active]
936154004113	Sortase and related acyltransferases [Cell envelope biogenesis, outer membrane]; Region: COG1247
936154004114	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
936154004115	Coenzyme A binding pocket [chemical binding]; other site
936154004116	Antibiotic biosynthesis monooxygenase; Region: ABM; cl10022
936154004117	Uncharacterized conserved protein [Function unknown]; Region: COG1359
936154004118	Amidohydrolase; Region: Amidohydro_2; pfam04909
936154004119	M14 family of metallocarboxypeptidases and related proteins; Region: Peptidase_M14_like; cl11393
936154004120	active site
936154004121	Zn binding site [ion binding]; other site
936154004122	TRAM domain; Region: TRAM; pfam01938
936154004123	SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase [Translation, ribosomal structure and biogenesis]; Region: TrmA; COG2265
936154004124	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
936154004125	S-adenosylmethionine binding site [chemical binding]; other site
936154004126	recombination regulator RecX; Provisional; Region: recX; PRK14135
936154004127	Staphylococcal protein of unknown function (DUF960); Region: DUF960; pfam06124
936154004128	RaiA ("ribosome-associated inhibitor A", also known as Protein Y (PY), YfiA, and SpotY,  is a stress-response protein that binds the ribosomal subunit interface and arrests translation by interfering with aminoacyl-tRNA binding to the ribosomal...; Region: RaiA; cd00552
936154004129	30S subunit binding site; other site
936154004130	Predicted amidophosphoribosyltransferases [General function prediction only]; Region: ComFC; COG1040
936154004131	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
936154004132	ATP binding site [chemical binding]; other site
936154004133	putative Mg++ binding site [ion binding]; other site
936154004134	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
936154004135	nucleotide binding region [chemical binding]; other site
936154004136	ATP-binding site [chemical binding]; other site
936154004137	Uncharacterized conserved protein [Function unknown]; Region: COG1739
936154004138	Uncharacterized protein family UPF0029; Region: UPF0029; pfam01205
936154004139	Domain of unknown function (DUF1949); Region: DUF1949; pfam09186
936154004140	Cysteine synthase [Amino acid transport and metabolism]; Region: CysK; COG0031
936154004141	CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS is a unique heme-containing enzyme that catalyzes a pyridoxal 5'-phosphate (PLP)-dependent condensation of serine and homocysteine to give cystathionine; Region: CBS_like; cd01561
936154004142	dimer interface [polypeptide binding]; other site
936154004143	pyridoxal 5'-phosphate binding site [chemical binding]; other site
936154004144	catalytic residue [active]
936154004145	hypothetical protein; Provisional; Region: PRK07252
936154004146	Predicted RNA binding protein (contains ribosomal protein S1 domain) [Translation, ribosomal structure and biogenesis]; Region: VacB; COG1098
936154004147	RNA binding site [nucleotide binding]; other site
936154004148	potential frameshift: common BLAST hit: gi|50914723|ref|YP_060695.1| peptidyl-prolyl cis-trans isomerase
936154004149	cyclophilin: cyclophilin-type peptidylprolyl cis- trans isomerases. This family contains eukaryotic, bacterial and archeal proteins which exhibit a peptidylprolyl cis- trans isomerases activity (PPIase, Rotamase) and in addition bind the...; Region: cyclophilin; cd00317
936154004150	active site
936154004151	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
936154004152	Response regulator receiver domain; Region: Response_reg; pfam00072
936154004153	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
936154004154	active site
936154004155	phosphorylation site [posttranslational modification]
936154004156	intermolecular recognition site; other site
936154004157	dimerization interface [polypeptide binding]; other site
936154004158	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: COG4585
936154004159	Histidine kinase; Region: HisKA_3; pfam07730
936154004160	Cell wall-active antibiotics response protein (DUF2154); Region: DUF2154; pfam09922
936154004161	Serine/Threonine protein kinases, catalytic domain; Region: S_TKc; smart00220
936154004162	Catalytic domain of Protein Kinases; Region: PKc; cd00180
936154004163	active site
936154004164	ATP binding site [chemical binding]; other site
936154004165	substrate binding site [chemical binding]; other site
936154004166	activation loop (A-loop); other site
936154004167	PASTA domain of bacterial serine/threonine kinase pknB-like proteins. PknB is a member of a group of related transmembrane sensor kinases present in many gram positive bacteria, which has been shown to regulate cell shape in Mycobacterium tubercolosis; Region: PASTA_pknB; cd06577
936154004168	Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and deduced catalytic mechanism of PP2C phosphatases are similar to the PP1, PP2A, PP2B family of protein Ser/Thr phosphatases, with which PP2C shares no sequence...; Region: PP2Cc; cd00143
936154004169	active site
936154004170	Methyltransferase domain; Region: Methyltransf_31; pfam13847
936154004171	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
936154004172	S-adenosylmethionine binding site [chemical binding]; other site
936154004173	methionyl-tRNA formyltransferase; Reviewed; Region: fmt; PRK00005
936154004174	Methionyl-tRNA formyltransferase, N-terminal hydrolase domain; Region: FMT_core_Met-tRNA-FMT_N; cd08646
936154004175	putative active site [active]
936154004176	substrate binding site [chemical binding]; other site
936154004177	putative cosubstrate binding site; other site
936154004178	catalytic site [active]
936154004179	C-terminal domain of Formyltransferase and other enzymes; Region: Met_tRNA_FMT_C; cd08704
936154004180	substrate binding site [chemical binding]; other site
936154004181	Primosomal protein N' (replication factor Y) - superfamily II helicase [DNA replication, recombination, and repair]; Region: PriA; COG1198
936154004182	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
936154004183	ATP binding site [chemical binding]; other site
936154004184	putative Mg++ binding site [ion binding]; other site
936154004185	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
936154004186	ATP-binding site [chemical binding]; other site
936154004187	DNA-directed RNA polymerase subunit omega; Reviewed; Region: rpoZ; PRK00392
936154004188	Guanylate kinase [Nucleotide transport and metabolism]; Region: Gmk; COG0194
936154004189	Guanosine monophosphate kinase (GMPK, EC 2.7.4.8), also known as guanylate kinase (GKase), catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to guanosine monophosphate (GMP) to yield adenosine diphosphate (ADP) and guanosine...; Region: GMPK; cd00071
936154004190	catalytic site [active]
936154004191	G-X2-G-X-G-K; other site
936154004192	hypothetical protein; Provisional; Region: PRK00106
936154004193	ATP synthase archaeal, H subunit; Region: AhaH; TIGR02926
936154004194	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
936154004195	Zn2+ binding site [ion binding]; other site
936154004196	Mg2+ binding site [ion binding]; other site
936154004197	S-ribosylhomocysteinase; Provisional; Region: PRK02260
936154004198	Predicted N6-adenine-specific DNA methylase [DNA replication, recombination, and repair]; Region: COG0116
936154004199	THUMP domain associated with S-adenosylmethionine-dependent methyltransferases; Region: THUMP_AdoMetMT; cd11715
936154004200	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
936154004201	cell division protein GpsB; Provisional; Region: PRK14127
936154004202	DivIVA domain; Region: DivI1A_domain; TIGR03544
936154004203	hypothetical protein; Provisional; Region: PRK13660
936154004204	Holliday junction-specific endonuclease; Reviewed; Region: recU; PRK02234
936154004205	Transglycosylase; Region: Transgly; pfam00912
936154004206	penicillin-binding protein, 1A family; Region: PBP_1a_fam; TIGR02074
936154004207	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
936154004208	Peptidase C1B subfamily (MEROPS database nomenclature); composed of eukaryotic bleomycin hydrolases (BH) and bacterial aminopeptidases C (pepC). The proteins of this subfamily contain a large insert relative to the C1A peptidase (papain) subfamily. BH is...; Region: Peptidase_C1B; cd00585
936154004209	trimer interface [polypeptide binding]; other site
936154004210	active site
936154004211	G bulge; other site
936154004212	NAD synthase [Coenzyme metabolism]; Region: NadE; COG0171
936154004213	NAD+ synthase is a homodimer, which catalyzes the final step in de novo nicotinamide adenine dinucleotide (NAD+) biosynthesis, an amide transfer from either ammonia or glutamine to nicotinic acid adenine dinucleotide (NaAD). The conversion of NaAD to NAD...; Region: NAD_synthase; cd00553
936154004214	homodimer interface [polypeptide binding]; other site
936154004215	NAD binding pocket [chemical binding]; other site
936154004216	ATP binding pocket [chemical binding]; other site
936154004217	Mg binding site [ion binding]; other site
936154004218	active-site loop [active]
936154004219	nicotinate phosphoribosyltransferase; Validated; Region: PRK09243
936154004220	Nicotinate phosphoribosyltransferase (NAPRTase), subgroup A. Nicotinate phosphoribosyltransferase catalyses the formation of NAMN and PPi from 5-phosphoribosy -1-pyrophosphate (PRPP) and nicotinic acid, this is the first, and also rate limiting, reaction...; Region: NAPRTase_A; cd01570
936154004221	active site
936154004222	CHAP domain; Region: CHAP; cl17642
936154004223	Peptidoglycan recognition proteins (PGRPs) are pattern recognition receptors that bind, and in certain cases, hydrolyze peptidoglycans (PGNs) of bacterial cell walls. PGRPs have been divided into three classes: short PGRPs (PGRP-S), that are small (20...; Region: PGRP; cd06583
936154004224	amidase catalytic site [active]
936154004225	Zn binding residues [ion binding]; other site
936154004226	substrate binding site [chemical binding]; other site
936154004227	SGNH_hydrolase, or GDSL_hydrolase, is a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely...; Region: SGNH_hydrolase; cd00229
936154004228	active site
936154004229	catalytic triad [active]
936154004230	oxyanion hole [active]
936154004231	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase; Region: Glucosaminidase; cl17361
936154004232	CHAP domain; Region: CHAP; cl17642
936154004233	Phage tail protein; Region: Sipho_tail; pfam05709
936154004234	Phage tail protein; Region: Sipho_tail; cl17486
936154004235	Phage-related protein [Function unknown]; Region: COG5412
936154004236	Phage major tail protein 2; Region: Phage_tail_2; cl11463
936154004237	acetoacetyl-CoA reductase; Region: AcAcCoA_reduct; TIGR01829
936154004238	Phage gp6-like head-tail connector protein; Region: Phage_connect_1; pfam05135
936154004239	Domain of unknown function (DUF4355); Region: DUF4355; pfam14265
936154004240	Phage Mu protein F like protein; Region: Phage_Mu_F; cl10072
936154004241	phage portal protein, SPP1 family; Region: portal_SPP1; TIGR01538
936154004242	Phage portal protein, SPP1 Gp6-like; Region: Phage_prot_Gp6; pfam05133
936154004243	Terminase small subunit; Region: Terminase_2; cl01513
936154004244	RecT family; Region: RecT; cl04285
936154004245	DnaD and phage-associated domain; Region: DnaD_dom; TIGR01446
936154004246	Helix-turn-helix domain; Region: HTH_36; pfam13730
936154004247	Phage anti-repressor protein [Transcription]; Region: COG3561
936154004248	Phage antirepressor protein KilAC domain; Region: ANT; pfam03374
936154004249	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
936154004250	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
936154004251	non-specific DNA binding site [nucleotide binding]; other site
936154004252	salt bridge; other site
936154004253	sequence-specific DNA binding site [nucleotide binding]; other site
936154004254	Predicted transcriptional regulator [Transcription]; Region: COG2932
936154004255	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
936154004256	Catalytic site [active]
936154004257	Host cell surface-exposed lipoprotein; Region: Lipoprotein_Ltp; pfam07553
936154004258	Host cell surface-exposed lipoprotein; Region: Lipoprotein_Ltp; pfam07553
936154004259	Integrase [DNA replication, recombination, and repair]; Region: XerC; COG0582
936154004260	phiLC3 phage and phage-related integrases, site-specific recombinases, DNA breaking-rejoining enzymes, C-terminal catalytic domain. This CD includes various bacterial (mainly gram positive) and phage integrases, including those similar to Lactococcus...; Region: INT_phiLC3_C; cd01189
936154004261	Int/Topo IB signature motif; other site
936154004262	CHAP domain; Region: CHAP; cl17642
936154004263	Peptidoglycan recognition proteins (PGRPs) are pattern recognition receptors that bind, and in certain cases, hydrolyze peptidoglycans (PGNs) of bacterial cell walls. PGRPs have been divided into three classes: short PGRPs (PGRP-S), that are small (20...; Region: PGRP; cd06583
936154004264	amidase catalytic site [active]
936154004265	Zn binding residues [ion binding]; other site
936154004266	substrate binding site [chemical binding]; other site
936154004267	SGNH_hydrolase, or GDSL_hydrolase, is a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely...; Region: SGNH_hydrolase; cd00229
936154004268	active site
936154004269	catalytic triad [active]
936154004270	oxyanion hole [active]
936154004271	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase; Region: Glucosaminidase; cl17361
936154004272	CHAP domain; Region: CHAP; cl17642
936154004273	Phage tail protein; Region: Sipho_tail; pfam05709
936154004274	Phage tail protein; Region: Sipho_tail; cl17486
936154004275	Phage-related protein [Function unknown]; Region: COG5412
936154004276	Phage major tail protein 2; Region: Phage_tail_2; cl11463
936154004277	Phage gp6-like head-tail connector protein; Region: Phage_connect_1; pfam05135
936154004278	Domain of unknown function (DUF4355); Region: DUF4355; pfam14265
936154004279	NAD+--asparagine ADP-ribosyltransferase [Signal transduction mechanisms]; Region: COG5585
936154004280	Phage Mu protein F like protein; Region: Phage_Mu_F; cl10072
936154004281	phage portal protein, SPP1 family; Region: portal_SPP1; TIGR01538
936154004282	Phage portal protein, SPP1 Gp6-like; Region: Phage_prot_Gp6; pfam05133
936154004283	phage transcriptional regulator, ArpU family; Region: phage_arpU; TIGR01637
936154004284	Protein of unknown function (DUF1642); Region: DUF1642; pfam07852
936154004285	Type I restriction-modification system methyltransferase subunit [Defense mechanisms]; Region: HsdM; COG0286
936154004286	PDDEXK-like domain of unknown function (DUF3799); Region: DUF3799; pfam12684
936154004287	RecT family; Region: RecT; pfam03837
936154004288	Replication initiation and membrane attachment; Region: DnaB_2; pfam07261
936154004289	AntA/AntB antirepressor; Region: AntA; cl01430
936154004290	Phage antirepressor protein KilAC domain; Region: ANT; pfam03374
936154004291	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
936154004292	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
936154004293	non-specific DNA binding site [nucleotide binding]; other site
936154004294	salt bridge; other site
936154004295	sequence-specific DNA binding site [nucleotide binding]; other site
936154004296	Predicted transcriptional regulator [Transcription]; Region: COG2932
936154004297	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
936154004298	Catalytic site [active]
936154004299	Integrase [DNA replication, recombination, and repair]; Region: XerC; COG0582
936154004300	phiLC3 phage and phage-related integrases, site-specific recombinases, DNA breaking-rejoining enzymes, C-terminal catalytic domain. This CD includes various bacterial (mainly gram positive) and phage integrases, including those similar to Lactococcus...; Region: INT_phiLC3_C; cd01189
936154004301	Int/Topo IB signature motif; other site
936154004302	Protein of unknown function (DUF1648); Region: DUF1648; pfam07853
936154004303	SdpI/YhfL protein family; Region: SdpI; pfam13630
936154004304	Human Ape1-like subfamily of the ExoIII family purinic/apyrimidinic (AP) endonucleases; Region: Ape1-like_AP-endo; cd09087
936154004305	active site
936154004306	putative catalytic site [active]
936154004307	DNA binding site [nucleotide binding]
936154004308	putative phosphate binding site [ion binding]; other site
936154004309	metal binding site A [ion binding]; metal-binding site
936154004310	AP binding site [nucleotide binding]; other site
936154004311	metal binding site B [ion binding]; metal-binding site
936154004312	DNA alkylation repair enzyme; Region: DNA_alkylation; pfam08713
936154004313	A new structural DNA glycosylase containing HEAT-like repeats; Region: AlkD_like_1; cd07064
936154004314	active site
936154004315	This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_16; cd07263
936154004316	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
936154004317	Escherichia coli PhnB and similar proteins; the E. coli phnB gene is found next to an operon involved in the cleavage of carbon-phosphorus bonds in unactivated alkylphosphonates; Region: PhnB_like; cd06588
936154004318	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
936154004319	dimer interface [polypeptide binding]; other site
936154004320	Arsenate Reductase (ArsC) family, unknown subfamily; uncharacterized proteins containing a CXXC motif with similarity to thioredoxin (TRX)-fold arsenic reductases, ArsC. Proteins containing a redox active CXXC motif like TRX and glutaredoxin (GRX)...; Region: ArsC_like; cd03036
936154004321	ArsC family; Region: ArsC; pfam03960
936154004322	putative ArsC-like catalytic residues; other site
936154004323	putative TRX-like catalytic residues [active]
936154004324	Methylated DNA-protein cysteine methyltransferase [DNA replication, recombination, and repair]; Region: Ada; COG0350
936154004325	The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445
936154004326	DNA binding site [nucleotide binding]
936154004327	active site
936154004328	Putative D-3-Phosphoglycerate Dehydrogenases, NAD-binding and catalytic domains; Region: PGDH_like_3; cd12174
936154004329	putative ligand binding site [chemical binding]; other site
936154004330	Phosphoglycerate dehydrogenase and related dehydrogenases [Amino acid transport and metabolism]; Region: SerA; COG0111
936154004331	putative NAD binding site [chemical binding]; other site
936154004332	putative catalytic site [active]
936154004333	C-terminal ACT (regulatory) domain of D-3-Phosphoglycerate Dehydrogenase (3PGDH) found in fungi and bacteria; Region: ACT_3PGDH; cd04901
936154004334	L-serine binding site [chemical binding]; other site
936154004335	ACT domain interface; other site
936154004336	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
936154004337	3-phosphoserine/phosphohydroxythreonine aminotransferase; Provisional; Region: PRK05355
936154004338	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
936154004339	catalytic residue [active]
936154004340	CutC family; Region: CutC; pfam03932
936154004341	Predicted methyltransferases [General function prediction only]; Region: COG0313
936154004342	Ribosomal RNA small subunit methyltransferase I, also known as rRNA (cytidine-2'-O-)-methyltransferase RsmI; Region: RsmI; cd11648
936154004343	putative homodimer interface [polypeptide binding]; other site
936154004344	putative SAM binding site [chemical binding]; other site
936154004345	DNA replication intiation control protein YabA; Reviewed; Region: PRK13169
936154004346	PSP1 C-terminal conserved region; Region: PSP1; cl00770
936154004347	DNA polymerase III subunit delta'; Validated; Region: PRK07276
936154004348	DNA polymerase III subunit delta'; Validated; Region: PRK08485
936154004349	thymidylate kinase; Validated; Region: tmk; PRK00698
936154004350	Thymidine monophosphate kinase (TMPK), also known as thymidylate kinase, catalyzes the phosphorylation of thymidine monophosphate (TMP) to thymidine diphosphate (TDP) utilizing ATP as its preferred phophoryl donor. TMPK represents the rate-limiting step...; Region: TMPK; cd01672
936154004351	TMP-binding site; other site
936154004352	ATP-binding site [chemical binding]; other site
936154004353	FOG: CBS domain [General function prediction only]; Region: COG0517
936154004354	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in  the acetoin utilization proteins in bacteria. Acetoin is a product of fermentative metabolism in many prokaryotic and eukaryotic microorganisms.  They produce...; Region: CBS_pair_ACT_assoc2; cd04585
936154004355	ACT domains are commonly involved in specifically binding an amino acid or other small ligand leading to regulation of the enzyme; Region: ACT; cd02116
936154004356	ABC-type branched-chain amino acid transport systems, ATPase component [Amino acid transport and metabolism]; Region: LivF; COG0410
936154004357	ATP-binding cassette domain of branched-chain amino acid transporter; Region: ABC_TM1139_LivF_branched; cd03224
936154004358	Walker A/P-loop; other site
936154004359	ATP binding site [chemical binding]; other site
936154004360	Q-loop/lid; other site
936154004361	ABC transporter signature motif; other site
936154004362	Walker B; other site
936154004363	D-loop; other site
936154004364	H-loop/switch region; other site
936154004365	ABC-type branched-chain amino acid transport systems, ATPase component [Amino acid transport and metabolism]; Region: LivG; COG0411
936154004366	ATP-binding cassette component of branched chain amino acids transport system; Region: ABC_Mj1267_LivG_branched; cd03219
936154004367	Walker A/P-loop; other site
936154004368	ATP binding site [chemical binding]; other site
936154004369	Q-loop/lid; other site
936154004370	ABC transporter signature motif; other site
936154004371	Walker B; other site
936154004372	D-loop; other site
936154004373	H-loop/switch region; other site
936154004374	ABC-type branched-chain amino acid transport system, permease component [Amino acid transport and metabolism]; Region: LivM; COG4177
936154004375	Transmembrane subunit (TM) of Escherichia coli LivM and related proteins. LivM is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of...; Region: TM_PBP1_LivM_like; cd06581
936154004376	TM-ABC transporter signature motif; other site
936154004377	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
936154004378	Transmembrane subunit (TM) of Escherichia coli LivH and related proteins. LivH is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of...; Region: TM_PBP1_LivH_like; cd06582
936154004379	TM-ABC transporter signature motif; other site
936154004380	ABC-type branched-chain amino acid transport systems, periplasmic component [Amino acid transport and metabolism]; Region: LivK; COG0683
936154004381	Type I periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems that are predicted to be involved in uptake of amino acids, peptides, or inorganic ions; Region: PBP1_ABC_ligand_binding_like_12; cd06347
936154004382	putative ligand binding site [chemical binding]; other site
936154004383	Protein of unknown function (DUF964); Region: DUF964; pfam06133
936154004384	Protease subunit of ATP-dependent Clp proteases [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: ClpP; COG0740
936154004385	Caseinolytic protease (ClpP) is an ATP-dependent, highly conserved serine protease; Region: S14_ClpP_2; cd07017
936154004386	oligomer interface [polypeptide binding]; other site
936154004387	active site residues [active]
936154004388	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
936154004389	active site
936154004390	Membrane protein involved in the export of O-antigen and teichoic acid [General function prediction only]; Region: RfbX; COG2244
936154004391	Stage V sporulation protein B, also known as Stage III sporulation protein F, and related proteins; Region: MATE_SpoVB_like; cd13124
936154004392	UDP-N-acetylmuramyl-tripeptide synthetase; Region: murE; TIGR01085
936154004393	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
936154004394	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
936154004395	ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components [Inorganic ion transport and metabolism / Coenzyme metabolism]; Region: FepC; COG1120
936154004396	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
936154004397	Walker A/P-loop; other site
936154004398	ATP binding site [chemical binding]; other site
936154004399	Q-loop/lid; other site
936154004400	ABC transporter signature motif; other site
936154004401	Walker B; other site
936154004402	D-loop; other site
936154004403	H-loop/switch region; other site
936154004404	Periplasmic binding protein FeuA.  These proteins have predicted to function as initial receptors in ABC transport of metal ions in some eubacterial species.  They belong to the TroA superfamily of periplasmic metal binding proteins that share a distinct...; Region: FeuA; cd01138
936154004405	Periplasmic binding protein; Region: Peripla_BP_2; pfam01497
936154004406	putative ligand binding residues [chemical binding]; other site
936154004407	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
936154004408	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
936154004409	ABC-ATPase subunit  interface; other site
936154004410	dimer interface [polypeptide binding]; other site
936154004411	putative PBP binding regions; other site
936154004412	FecCD transport family; Region: FecCD; pfam01032
936154004413	ABC-ATPase subunit  interface; other site
936154004414	dimer interface [polypeptide binding]; other site
936154004415	Domain of unknown function (DUF1803); Region: DUF1803; pfam08820
936154004416	Domain of unknown function (DUF1803); Region: DUF1803; pfam08820
936154004417	putative manganese-dependent inorganic pyrophosphatase; Provisional; Region: PRK05427
936154004418	DHH family; Region: DHH; pfam01368
936154004419	DHHA2 domain; Region: DHHA2; pfam02833
936154004420	pyruvate formate-lyase 1-activating enzyme; Region: PFLA; TIGR02493
936154004421	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
936154004422	FeS/SAM binding site; other site
936154004423	Hemolysins and related proteins containing CBS domains [General function prediction only]; Region: TlyC; COG1253
936154004424	Domain of unknown function DUF21; Region: DUF21; pfam01595
936154004425	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
936154004426	Transporter associated domain; Region: CorC_HlyC; pfam03471
936154004427	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
936154004428	S-adenosylmethionine binding site [chemical binding]; other site
936154004429	ABC-2 family transporter protein; Region: ABC2_membrane_2; pfam12679
936154004430	ABC-2 family transporter protein; Region: ABC2_membrane_4; pfam12730
936154004431	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
936154004432	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
936154004433	Walker A/P-loop; other site
936154004434	ATP binding site [chemical binding]; other site
936154004435	Q-loop/lid; other site
936154004436	ABC transporter signature motif; other site
936154004437	Walker B; other site
936154004438	D-loop; other site
936154004439	H-loop/switch region; other site
936154004440	Predicted Fe-S oxidoreductase [General function prediction only]; Region: COG1242
936154004441	Integrase [DNA replication, recombination, and repair]; Region: XerC; COG0582
936154004442	phiLC3 phage and phage-related integrases, site-specific recombinases, DNA breaking-rejoining enzymes, C-terminal catalytic domain. This CD includes various bacterial (mainly gram positive) and phage integrases, including those similar to Lactococcus...; Region: INT_phiLC3_C; cd01189
936154004443	Int/Topo IB signature motif; other site
936154004444	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
936154004445	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
936154004446	non-specific DNA binding site [nucleotide binding]; other site
936154004447	salt bridge; other site
936154004448	sequence-specific DNA binding site [nucleotide binding]; other site
936154004449	Uncharacterized phage-encoded protein [Function unknown]; Region: COG3646
936154004450	Phage regulatory protein Rha (Phage_pRha); Region: Phage_pRha; pfam09669
936154004451	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cl17200
936154004452	Primase C terminal 1 (PriCT-1); Region: PriCT_1; pfam08708
936154004453	D5 N terminal like; Region: D5_N; pfam08706
936154004454	phage/plasmid primase, P4 family, C-terminal domain; Region: primase_Cterm; TIGR01613
936154004455	Poxvirus D5 protein-like; Region: Pox_D5; pfam03288
936154004456	phage transcriptional regulator, ArpU family; Region: phage_arpU; TIGR01637
936154004457	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
936154004458	PAP2_like_2 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This subgroup, which is specific to bacteria, lacks functional characterization and may act as a membrane-associated lipid phosphatase; Region: PAP2_like_2; cd03392
936154004459	active site
936154004460	Predicted membrane protein [Function unknown]; Region: COG3601
936154004461	Protein of unknown function (DUF3816); Region: DUF3816; pfam12822
936154004462	Predicted rRNA methylase (SpoU class) [Translation, ribosomal structure and biogenesis]; Region: CspR; COG0219
936154004463	16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases [Translation, ribosomal structure and biogenesis]; Region: RsuA; COG1187
936154004464	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
936154004465	RNA binding surface [nucleotide binding]; other site
936154004466	Pseudouridine synthases, RsuA subfamily; Region: PseudoU_synth_RsuA_like; cd02870
936154004467	active site
936154004468	segregation and condensation protein B; Reviewed; Region: scpB; PRK00135
936154004469	segregation and condensation protein A; Reviewed; Region: scpA; PRK00104
936154004470	site-specific tyrosine recombinase XerD-like protein; Reviewed; Region: xerD; PRK02436
936154004471	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
936154004472	DNA breaking-rejoining enzymes, intergrase/recombinases, C-terminal catalytic domain. The tyrosine recombinase/integrase family share the same catalytic domain containing six conserved active site residues. The best-studied members of this diverse family...; Region: INT_REC_C; cd01182
936154004473	DNA binding site [nucleotide binding]
936154004474	active site
936154004475	Int/Topo IB signature motif; other site
936154004476	catalytic residues [active]
936154004477	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
936154004478	Escherichia coli YfcE and related proteins, metallophosphatase domain; Region: MPP_YfcE; cd00841
936154004479	active site
936154004480	metal binding site [ion binding]; metal-binding site
936154004481	homotetramer interface [polypeptide binding]; other site
936154004482	putative deoxyribonucleotide triphosphate pyrophosphatase/unknown domain fusion protein; Reviewed; Region: PRK02491
936154004483	NTPase/HAM1.  This family consists of the HAM1 protein and pyrophosphate-releasing xanthosine/ inosine triphosphatase. HAM1 protects the cell against mutagenesis by the base analog 6-N-hydroxylaminopurine (HAP) in E. Coli and S. cerevisiae. A...; Region: HAM1; cd00515
936154004484	active site
936154004485	dimerization interface [polypeptide binding]; other site
936154004486	glutamate racemase; Provisional; Region: PRK00865
936154004487	Diaminopimelate decarboxylase [Amino acid transport and metabolism]; Region: LysA; COG0019
936154004488	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Diaminopimelate Decarboxylase; Region: PLPDE_III_DapDC; cd06828
936154004489	active site
936154004490	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
936154004491	substrate binding site [chemical binding]; other site
936154004492	catalytic residues [active]
936154004493	dimer interface [polypeptide binding]; other site
936154004494	Integral membrane protein, interacts with FtsH [General function prediction only]; Region: COG0670
936154004495	Bacterial BAX inhibitor (BI)-1/YccA-like proteins; Region: BI-1-like_bacterial; cd10432
936154004496	Predicted HD superfamily hydrolase [General function prediction only]; Region: COG1418
936154004497	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cl17215
936154004498	Protein Kinases, catalytic domain; Region: PKc_like; cl09925
936154004499	substrate binding site [chemical binding]; other site
936154004500	activation loop (A-loop); other site
936154004501	rRNA methylases [Translation, ribosomal structure and biogenesis]; Region: SpoU; COG0566
936154004502	RNA 2'-O ribose methyltransferase substrate binding; Region: SpoU_sub_bind; pfam08032
936154004503	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
936154004504	acylphosphatase; Provisional; Region: PRK14434
936154004505	OxaA-like protein precursor; Provisional; Region: PRK02463
936154004506	membrane protein insertase, YidC/Oxa1 family, C-terminal domain; Region: yidC_oxa1_cterm; TIGR03592
936154004507	transcription elongation factor GreA; Reviewed; Region: greA; PRK00226
936154004508	Transcription elongation factor, N-terminal; Region: GreA_GreB_N; pfam03449
936154004509	Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272
936154004510	Aminodeoxychorismate lyase [Coenzyme transport and metabolism]; Region: COG1559
936154004511	proteins similar to Escherichia coli yceG; Region: yceG_like; cd08010
936154004512	dimerization interface [polypeptide binding]; other site
936154004513	UDP-N-acetylmuramate--L-alanine ligase; Provisional; Region: murC; PRK00421
936154004514	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
936154004515	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
936154004516	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
936154004517	SWIM zinc finger; Region: SWIM; pfam04434
936154004518	Bacterial SNF2 helicase associated; Region: SNF2_assoc; pfam08455
936154004519	SNF2 family N-terminal domain; Region: SNF2_N; pfam00176
936154004520	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
936154004521	ATP binding site [chemical binding]; other site
936154004522	putative Mg++ binding site [ion binding]; other site
936154004523	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
936154004524	nucleotide binding region [chemical binding]; other site
936154004525	ATP-binding site [chemical binding]; other site
936154004526	GTP-binding protein Der; Reviewed; Region: PRK00093
936154004527	EngA1 GTPase contains the first domain of EngA; Region: EngA1; cd01894
936154004528	G1 box; other site
936154004529	GTP/Mg2+ binding site [chemical binding]; other site
936154004530	Switch I region; other site
936154004531	G2 box; other site
936154004532	Switch II region; other site
936154004533	G3 box; other site
936154004534	G4 box; other site
936154004535	G5 box; other site
936154004536	EngA2 GTPase contains the second domain of EngA; Region: EngA2; cd01895
936154004537	G1 box; other site
936154004538	GTP/Mg2+ binding site [chemical binding]; other site
936154004539	Switch I region; other site
936154004540	G2 box; other site
936154004541	G3 box; other site
936154004542	Switch II region; other site
936154004543	G4 box; other site
936154004544	G5 box; other site
936154004545	primosomal protein DnaI; Reviewed; Region: PRK08939
936154004546	Primosomal protein DnaI N-terminus; Region: DnaI_N; pfam07319
936154004547	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
936154004548	Walker A motif; other site
936154004549	ATP binding site [chemical binding]; other site
936154004550	Walker B motif; other site
936154004551	Replication initiation/membrane attachment protein [DNA replication, recombination, and repair]; Region: DnaB; COG3611
936154004552	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
936154004553	HAMP domain; Region: HAMP; pfam00672
936154004554	dimerization interface [polypeptide binding]; other site
936154004555	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
936154004556	dimer interface [polypeptide binding]; other site
936154004557	phosphorylation site [posttranslational modification]
936154004558	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
936154004559	ATP binding site [chemical binding]; other site
936154004560	Mg2+ binding site [ion binding]; other site
936154004561	G-X-G motif; other site
936154004562	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
936154004563	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
936154004564	active site
936154004565	phosphorylation site [posttranslational modification]
936154004566	intermolecular recognition site; other site
936154004567	dimerization interface [polypeptide binding]; other site
936154004568	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
936154004569	DNA binding site [nucleotide binding]
936154004570	Uncharacterized ACR, COG1399; Region: DUF177; cl00616
936154004571	heat shock protein HtpX; Provisional; Region: PRK04897
936154004572	Uncharacterized conserved protein [Function unknown]; Region: LemA; COG1704
936154004573	Predicted S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division [Cell envelope biogenesis, outer membrane]; Region: GidB; COG0357
936154004574	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
936154004575	S-adenosylmethionine binding site [chemical binding]; other site
936154004576	Trk-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: TrkG; COG0168
936154004577	potassium uptake protein, TrkH family; Region: 2a38; TIGR00933
936154004578	K+ transport systems, NAD-binding component [Inorganic ion transport and metabolism]; Region: TrkA; COG0569
936154004579	TrkA-N domain; Region: TrkA_N; pfam02254
936154004580	TrkA-C domain; Region: TrkA_C; pfam02080
936154004581	ABC-type metal ion transport system, permease component [Inorganic ion transport and metabolism]; Region: AbcD; COG2011
936154004582	DL-methionine transporter ATP-binding subunit; Provisional; Region: metN; PRK11153
936154004583	ATP-binding cassette domain of methionine transporter; Region: ABC_MetN_methionine_transporter; cd03258
936154004584	Walker A/P-loop; other site
936154004585	ATP binding site [chemical binding]; other site
936154004586	Q-loop/lid; other site
936154004587	ABC transporter signature motif; other site
936154004588	Walker B; other site
936154004589	D-loop; other site
936154004590	H-loop/switch region; other site
936154004591	NIL domain; Region: NIL; pfam09383
936154004592	hypothetical protein; Provisional; Region: PRK06446
936154004593	Uncharacterized M20 Dipeptidases; Region: M20_dipept_like_4; cd05681
936154004594	metal binding site [ion binding]; metal-binding site
936154004595	dimer interface [polypeptide binding]; other site
936154004596	ABC-type metal ion transport system, periplasmic component/surface antigen [Inorganic ion transport and metabolism]; Region: NlpA; COG1464
936154004597	NLPA lipoprotein; Region: Lipoprotein_9; pfam03180
936154004598	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
936154004599	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
936154004600	substrate binding pocket [chemical binding]; other site
936154004601	membrane-bound complex binding site; other site
936154004602	hinge residues; other site
936154004603	hypothetical protein; Provisional; Region: PRK12378
936154004604	Predicted nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: COG0702
936154004605	triphenylmethane reductase (TMR)-like proteins, NMRa-like, atypical (a) SDRs; Region: TMR_SDR_a; cd05269
936154004606	NADP binding site [chemical binding]; other site
936154004607	Helix-Turn-Helix DNA binding domain of the transcription regulators TipAL, Mta, and SkgA; Region: HTH_TipAL-Mta; cd01106
936154004608	MerR HTH family regulatory protein; Region: MerR_1; pfam13411
936154004609	DNA binding residues [nucleotide binding]
936154004610	dimer interface [polypeptide binding]; other site
936154004611	TipAS antibiotic-recognition domain; Region: TipAS; pfam07739
936154004612	SAM-dependent methyltransferases [Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only]; Region: SmtA; COG0500
936154004613	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
936154004614	S-adenosylmethionine binding site [chemical binding]; other site
936154004615	iojap-like ribosome-associated protein; Region: iojap_ybeB; TIGR00090
936154004616	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
936154004617	Zn2+ binding site [ion binding]; other site
936154004618	Mg2+ binding site [ion binding]; other site
936154004619	nicotinic acid mononucleotide adenylyltransferase; Provisional; Region: nadD; PRK00071
936154004620	Nicotinamide/nicotinate mononucleotide adenylyltransferase; Region: NMNAT; cd02165
936154004621	active site
936154004622	(T/H)XGH motif; other site
936154004623	GTPase YqeH; Provisional; Region: PRK13796
936154004624	Circularly permuted YqeH GTPase; Region: YqeH; cd01855
936154004625	GTP/Mg2+ binding site [chemical binding]; other site
936154004626	G4 box; other site
936154004627	G5 box; other site
936154004628	G1 box; other site
936154004629	Switch I region; other site
936154004630	G2 box; other site
936154004631	G3 box; other site
936154004632	Switch II region; other site
936154004633	Predicted hydrolase of the HAD superfamily [General function prediction only]; Region: COG2179
936154004634	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
936154004635	active site
936154004636	motif I; other site
936154004637	motif II; other site
936154004638	RNA polymerase sigma factor, sigma-70 family; Region: sigma70-ECF; TIGR02937
936154004639	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppF; COG1124
936154004640	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
936154004641	Walker A/P-loop; other site
936154004642	ATP binding site [chemical binding]; other site
936154004643	Q-loop/lid; other site
936154004644	ABC transporter signature motif; other site
936154004645	Walker B; other site
936154004646	D-loop; other site
936154004647	H-loop/switch region; other site
936154004648	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
936154004649	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppD; COG0444
936154004650	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
936154004651	Walker A/P-loop; other site
936154004652	ATP binding site [chemical binding]; other site
936154004653	Q-loop/lid; other site
936154004654	ABC transporter signature motif; other site
936154004655	Walker B; other site
936154004656	D-loop; other site
936154004657	H-loop/switch region; other site
936154004658	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
936154004659	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
936154004660	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
936154004661	dimer interface [polypeptide binding]; other site
936154004662	conserved gate region; other site
936154004663	putative PBP binding loops; other site
936154004664	ABC-ATPase subunit interface; other site
936154004665	ABC-type oligopeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: OppA; COG4166
936154004666	The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold; Region: PBP2_OppA; cd08504
936154004667	peptide binding site [polypeptide binding]; other site
936154004668	D-alanyl-D-alanine carboxypeptidase [Cell envelope biogenesis, outer membrane]; Region: DacC; COG1686
936154004669	Beta-lactamase enzyme family; Region: Beta-lactamase2; cl17872
936154004670	Penicillin-binding protein 5, C-terminal domain; Region: PBP5_C; smart00936
936154004671	D-alanyl-D-alanine carboxypeptidase; Region: Peptidase_S11; pfam00768
936154004672	D-alanyl-D-alanine carboxypeptidase; Region: Peptidase_S11; pfam00768
936154004673	Beta-lactamase enzyme family; Region: Beta-lactamase2; cl17872
936154004674	cysteine desulfurase activator complex subunit SufB; Provisional; Region: PRK11814; cl03223
936154004675	FeS assembly protein SufB; Region: sufB; TIGR01980
936154004676	NifU homolog involved in Fe-S cluster formation [Energy production and conversion]; Region: IscU; COG0822
936154004677	Iron-sulfur cluster scaffold-like proteins; Region: IscU_like; cd06664
936154004678	trimerization site [polypeptide binding]; other site
936154004679	active site
936154004680	Selenocysteine lyase/Cysteine desulfurase [Posttranslational modification, protein turnover, chaperones]; Region: csdA; COG0520
936154004681	Cysteine desulfurase (SufS)-like. This family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to cysteine desulfurase (SufS) and selenocysteine lyase. SufS...; Region: SufS_like; cd06453
936154004682	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
936154004683	catalytic residue [active]
936154004684	Cysteine desulfurase activator SufB [Posttranslational modification, protein turnover, chaperones]; Region: SufB; COG0719
936154004685	FeS assembly protein SufD; Region: sufD; TIGR01981
936154004686	Cysteine desulfurase activator ATPase [Posttranslational modification, protein turnover, chaperones]; Region: sufC; COG0396
936154004687	ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Region: ABC_FeS_Assembly; cd03217
936154004688	Walker A/P-loop; other site
936154004689	ATP binding site [chemical binding]; other site
936154004690	Q-loop/lid; other site
936154004691	ABC transporter signature motif; other site
936154004692	Walker B; other site
936154004693	D-loop; other site
936154004694	H-loop/switch region; other site
936154004695	UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase [Cell envelope biogenesis, outer membrane]; Region: Rfe; COG0472
936154004696	This subfamily contains Escherichia coli WecA, Bacillus subtilis TagO and related proteins. WecA is an UDP-N-acetylglucosamine (GlcNAc):undecaprenyl-phosphate (Und-P) GlcNAc-1-phosphate transferase that catalyzes the formation of a phosphodiester bond...; Region: GT_WecA_like; cd06853
936154004697	Mg++ binding site [ion binding]; other site
936154004698	putative catalytic motif [active]
936154004699	substrate binding site [chemical binding]; other site
936154004700	adaptor protein; Provisional; Region: PRK02315
936154004701	undecaprenyl pyrophosphate phosphatase; Reviewed; Region: PRK00281
936154004702	Predicted membrane protein (DUF2207); Region: DUF2207; pfam09972
936154004703	Predicted membrane protein (DUF2207); Region: DUF2207; pfam09972
936154004704	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
936154004705	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
936154004706	substrate binding pocket [chemical binding]; other site
936154004707	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
936154004708	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
936154004709	Walker A/P-loop; other site
936154004710	ATP binding site [chemical binding]; other site
936154004711	Q-loop/lid; other site
936154004712	HflC protein; Region: hflC; TIGR01932
936154004713	A subgroup of the band 7 domain of flotillin (reggie) like proteins. This subgroup contains proteins similar to stomatin, prohibitin, flotillin, HlfK/C and podicin.  Many of these band 7 domain-containing proteins are lipid raft-associated.  Individual...; Region: Band_7_4; cd03407
936154004714	DAK2 domain fusion protein YloV; Region: YloV; TIGR03599
936154004715	DAK2 domain; Region: Dak2; pfam02734
936154004716	CsbD-like; Region: CsbD; pfam05532
936154004717	50S ribosomal protein L28; Reviewed; Region: rpmB; PRK00359
936154004718	fructose-bisphosphate aldolase; Provisional; Region: PRK09197
936154004719	Tagatose-1,6-bisphosphate (TBP) aldolase and related Type B Class II aldolases. TBP aldolase is a tetrameric class II aldolase that catalyzes the reversible condensation of dihydroxyacetone phosphate with glyceraldehyde 3-phsophate to produce tagatose 1; Region: TBP_aldolase_IIB; cd00947
936154004720	intersubunit interface [polypeptide binding]; other site
936154004721	active site
936154004722	zinc binding site [ion binding]; other site
936154004723	Na+ binding site [ion binding]; other site
936154004724	Hydrolases of the alpha/beta superfamily [General function prediction only]; Region: COG1073
936154004725	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
936154004726	LrgB-like family; Region: LrgB; cl00596
936154004727	murein hydrolase regulator LrgA; Provisional; Region: PRK04125
936154004728	two-component response regulator; Provisional; Region: PRK14084
936154004729	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
936154004730	active site
936154004731	phosphorylation site [posttranslational modification]
936154004732	intermolecular recognition site; other site
936154004733	dimerization interface [polypeptide binding]; other site
936154004734	LytTr DNA-binding domain; Region: LytTR; smart00850
936154004735	GAF domain; Region: GAF_3; pfam13492
936154004736	Histidine kinase; Region: His_kinase; pfam06580
936154004737	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
936154004738	ATP binding site [chemical binding]; other site
936154004739	Mg2+ binding site [ion binding]; other site
936154004740	G-X-G motif; other site
936154004741	5TMR of 5TMR-LYT; Region: 5TM-5TMR_LYT; pfam07694
936154004742	CTP synthetase; Validated; Region: pyrG; PRK05380
936154004743	CTP synthetase (CTPs) is a two-domain protein, which consists of an N-terminal synthetase domain and C-terminal glutaminase domain. The enzymes hydrolyze the amide bond of glutamine to ammonia and glutamate at the glutaminase domains and transfer nascent...; Region: CTGs; cd03113
936154004744	Catalytic site [active]
936154004745	active site
936154004746	UTP binding site [chemical binding]; other site
936154004747	Type 1 glutamine amidotransferase (GATase1) domain found in Cytidine Triphosphate Synthetase; Region: GATase1_CTP_Synthase; cd01746
936154004748	active site
936154004749	putative oxyanion hole; other site
936154004750	catalytic triad [active]
936154004751	DNA-directed RNA polymerase delta subunit; Region: RNA_pol_delta; pfam05066
936154004752	Predicted phosphatase/phosphohexomutase [General function prediction only]; Region: COG0637
936154004753	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
936154004754	motif II; other site
936154004755	trigger factor; Provisional; Region: tig; PRK01490
936154004756	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
936154004757	Bacterial trigger factor protein (TF) C-terminus; Region: Trigger_C; pfam05698
936154004758	Small-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscS; COG0668
936154004759	Mechanosensitive ion channel; Region: MS_channel; pfam00924
936154004760	hypothetical protein; Provisional; Region: PRK13690
936154004761	ECF-type riboflavin transporter, S component; Region: ECF-ribofla_trS; pfam07155
936154004762	4-amino-5-hydroxymethyl-2-methyl-pyrimidine phosphate kinase (HMPP-kinase) catalyzes two consecutive phosphorylation steps in the thiamine phosphate biosynthesis pathway, leading to the synthesis of vitamin B1. The first step is the phosphorylation of...; Region: HMPP_kinase; cd01169
936154004763	substrate binding site [chemical binding]; other site
936154004764	dimer interface [polypeptide binding]; other site
936154004765	ATP binding site [chemical binding]; other site
936154004766	tRNA pseudouridine synthase A; Validated; Region: truA; PRK00021
936154004767	Eukaryotic and bacterial pseudouridine synthases similar to E.  coli TruA; Region: PseudoU_synth_EcTruA; cd02570
936154004768	dimerization interface 3.5A [polypeptide binding]; other site
936154004769	active site
936154004770	aspartate kinase; Reviewed; Region: PRK09034
936154004771	AAK_AKiii-YclM-BS: Amino Acid Kinase Superfamily (AAK), AKiii-YclM-BS; this CD includes the N-terminal catalytic aspartokinase (AK) domain of the lysine plus threonine-sensitive aspartokinase isoenzyme AKIII, a monofunctional class enzyme found in...; Region: AAK_AKiii-YclM-BS; cd04245
936154004772	putative catalytic residues [active]
936154004773	putative nucleotide binding site [chemical binding]; other site
936154004774	putative aspartate binding site [chemical binding]; other site
936154004775	ACT domains located C-terminal to the catalytic domain of the lysine plus threonine-sensitive aspartokinase isoenzyme AKIII; Region: ACT_AKiii-YclM-BS_1; cd04911
936154004776	allosteric regulatory residue; other site
936154004777	ACT domains located C-terminal to the catalytic domain of the lysine plus threonine-sensitive aspartokinase isoenzyme AKIII; Region: ACT_AKiii-YclM-BS_2; cd04916
936154004778	Uncharacterized conserved protein [Function unknown]; Region: COG1912
936154004779	hypothetical protein; Provisional; Region: PRK13661
936154004780	ABC-type cobalt transport system, ATPase component [Inorganic ion transport and metabolism]; Region: CbiO; COG1122
936154004781	First domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain1; cd03225
936154004782	Walker A/P-loop; other site
936154004783	ATP binding site [chemical binding]; other site
936154004784	Q-loop/lid; other site
936154004785	ABC transporter signature motif; other site
936154004786	Walker B; other site
936154004787	D-loop; other site
936154004788	H-loop/switch region; other site
936154004789	ATP-binding cassette cobalt transporter; Region: DUF3744; pfam12558
936154004790	ABC-type cobalt transport system, ATPase component [Inorganic ion transport and metabolism]; Region: CbiO; COG1122
936154004791	First domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain1; cd03225
936154004792	Walker A/P-loop; other site
936154004793	ATP binding site [chemical binding]; other site
936154004794	Q-loop/lid; other site
936154004795	ABC transporter signature motif; other site
936154004796	Walker B; other site
936154004797	D-loop; other site
936154004798	H-loop/switch region; other site
936154004799	ABC-type cobalt transport system, permease component CbiQ and related transporters [Inorganic ion transport and metabolism]; Region: CbiQ; COG0619
936154004800	Predicted membrane protein [Function unknown]; Region: COG1511
936154004801	YhgE/Pip N-terminal domain; Region: pip_yhgE_Nterm; TIGR03061
936154004802	X-X-X-Leu-X-X-Gly heptad repeats; Region: xxxLxxG_by_4; TIGR03057
936154004803	YhgE/Pip C-terminal domain; Region: pip_yhgE_Cterm; TIGR03062
936154004804	LPXTG-motif cell wall anchor domain; Region: LPXTG_anchor; TIGR01167
936154004805	Predicted glutamine amidotransferases [General function prediction only]; Region: COG2071
936154004806	Subgroup of proteins having the Type 1 glutamine amidotransferase (GATase1) domain; Region: GATase1_2; cd01745
936154004807	catalytic triad [active]
936154004808	GBS Bsp-like repeat; Region: GBS_Bsp-like; pfam08481
936154004809	GBS Bsp-like repeat; Region: GBS_Bsp-like; pfam08481
936154004810	GBS Bsp-like repeat; Region: GBS_Bsp-like; pfam08481
936154004811	GBS Bsp-like repeat; Region: GBS_Bsp-like; pfam08481
936154004812	GBS Bsp-like repeat; Region: GBS_Bsp-like; pfam08481
936154004813	Beta-lactamase enzyme family; Region: Beta-lactamase2; cl17872
936154004814	Fibronectin-binding protein (FBP); Region: FBP; pfam07299
936154004815	Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis]; Region: RimL; COG1670
936154004816	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
936154004817	Domain of unknown function (DUF336); Region: DUF336; cl01249
936154004818	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
936154004819	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
936154004820	ligand binding site [chemical binding]; other site
936154004821	flexible hinge region; other site
936154004822	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cd00092
936154004823	putative switch regulator; other site
936154004824	non-specific DNA interactions [nucleotide binding]; other site
936154004825	DNA binding site [nucleotide binding]
936154004826	sequence specific DNA binding site [nucleotide binding]; other site
936154004827	putative cAMP binding site [chemical binding]; other site
936154004828	heavy metal translocating P-type ATPase; Region: ATPase-IB_hvy; TIGR01525
936154004829	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
936154004830	Soluble P-type ATPase [General function prediction only]; Region: COG4087
936154004831	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) MazG-like domain found in mouse RS21-C6 protein and its homologs; Region: NTP-PPase_RS21-C6_like; cd11537
936154004832	homodimer interface [polypeptide binding]; other site
936154004833	chemical substrate binding site [chemical binding]; other site
936154004834	oligomer interface [polypeptide binding]; other site
936154004835	metal binding site [ion binding]; metal-binding site
936154004836	GIY-YIG domain of uncharacterized bacterial protein structurally related to COG3410; Region: GIY-YIG_COG3410; cd10439
936154004837	GIY-YIG motif/motif A; other site
936154004838	putative active site [active]
936154004839	putative metal binding site [ion binding]; other site
936154004840	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cl17189
936154004841	Uncharacterized conserved protein (DUF2075); Region: DUF2075; pfam09848
936154004842	Walker A motif; other site
936154004843	ATP binding site [chemical binding]; other site
936154004844	Walker B motif; other site
936154004845	Uncharacterized conserved protein [Function unknown]; Region: COG3410
936154004846	Ribosomal protein S9/S16; Region: Ribosomal_S9; cl00334
936154004847	SIR2-like domain; Region: SIR2_2; pfam13289
936154004848	SIR2 superfamily of proteins includes silent information regulator 2 (Sir2) enzymes which catalyze NAD+-dependent protein/histone deacetylation, where the acetyl group from the lysine epsilon-amino group is transferred to the ADP-ribose moiety of NAD+; Region: SIR2; cl00195
936154004849	30S ribosomal protein S9; Reviewed; Region: rpsI; PRK00132
936154004850	Ribosomal protein L13.  Protein L13, a large ribosomal subunit protein, is one of five proteins required for an early folding intermediate of 23S rRNA in the assembly of the large subunit. L13 is situated on the bottom of the large subunit, near the...; Region: Ribosomal_L13; cd00392
936154004851	23S rRNA interface [nucleotide binding]; other site
936154004852	L3 interface [polypeptide binding]; other site
936154004853	EDD domain protein, DegV family; Region: DegV; TIGR00762
936154004854	Uncharacterized protein, DegV family COG1307; Region: DegV; pfam02645
936154004855	YacP-like NYN domain; Region: NYN_YacP; cl01491
936154004856	rRNA methylase, putative, group 3; Region: rRNA_methyl_3; TIGR00186
936154004857	RNA 2'-O ribose methyltransferase substrate binding; Region: SpoU_sub_bind; pfam08032
936154004858	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
936154004859	FlgD Tudor-like domain; Region: FLgD_tudor; pfam13861
936154004860	Ribonuclease III family protein [Replication, recombination, and    repair]; Region: COG1939
936154004861	active site
936154004862	metal binding site [ion binding]; metal-binding site
936154004863	dimerization interface [polypeptide binding]; other site
936154004864	cysteinyl-tRNA synthetase; Validated; Region: cysS; PRK00260
936154004865	catalytic core domain of cysteinyl tRNA synthetase; Region: CysRS_core; cd00672
936154004866	active site
936154004867	HIGH motif; other site
936154004868	catalytic core domain of cysteinyl tRNA synthetase; Region: CysRS_core; cd00672
936154004869	KMSKS motif; other site
936154004870	Anticodon-binding domain of class Ia aminoacyl tRNA synthetases and similar domains; Region: Anticodon_Ia_like; cl12020
936154004871	tRNA binding surface [nucleotide binding]; other site
936154004872	anticodon binding site; other site
936154004873	serine O-acetyltransferase; Region: cysE; TIGR01172
936154004874	Serine acetyltransferase (SAT): SAT catalyzes the CoA-dependent acetylation of the side chain hydroxyl group of L-serine to form O-acetylserine, as the first step of a two-step biosynthetic pathway in bacteria and plants leading to the formation of...; Region: LbH_SAT; cd03354
936154004875	trimer interface [polypeptide binding]; other site
936154004876	active site
936154004877	substrate binding site [chemical binding]; other site
936154004878	CoA binding site [chemical binding]; other site
936154004879	polynucleotide phosphorylase/polyadenylase; Provisional; Region: PRK11824
936154004880	Polyribonucleotide nucleotidyltransferase, repeat 1; Region: RNase_PH_PNPase_1; cd11363
936154004881	RNase E interface [polypeptide binding]; other site
936154004882	trimer interface [polypeptide binding]; other site
936154004883	Polyribonucleotide nucleotidyltransferase, repeat 2; Region: RNase_PH_PNPase_2; cd11364
936154004884	RNase E interface [polypeptide binding]; other site
936154004885	trimer interface [polypeptide binding]; other site
936154004886	active site
936154004887	Polynucleotide phosphorylase (PNPase) K homology RNA-binding domain (KH). PNPase is a polyribonucleotide nucleotidyl transferase that degrades mRNA in prokaryotes and plant chloroplasts. The C-terminal region of PNPase contains domains homologous to...; Region: PNPase_KH; cd02393
936154004888	S1_PNPase: Polynucleotide phosphorylase (PNPase), ), S1-like RNA-binding domain. PNPase  is a polyribonucleotide nucleotidyl transferase that degrades mRNA. It is a trimeric multidomain protein. The C-terminus contains the S1 domain which binds ssRNA; Region: S1_PNPase; cd04472
936154004889	RNA binding site [nucleotide binding]; other site
936154004890	domain interface; other site
936154004891	Ribosomal protein S15 (prokaryotic)_S13 (eukaryotic) binds the central domain of 16S rRNA and is required for assembly of the small ribosomal subunit and for intersubunit association, thus representing a key element in the assembly of the whole ribosome; Region: Ribosomal_S15p_S13e; cd00353
936154004892	16S/18S rRNA binding site [nucleotide binding]; other site
936154004893	S13e-L30e interaction site [polypeptide binding]; other site
936154004894	25S rRNA binding site [nucleotide binding]; other site
936154004895	Ppx/GppA phosphatase family; Region: Ppx-GppA; pfam02541
936154004896	Polyphosphate kinase middle domain; Region: PP_kinase; pfam02503
936154004897	Polyphosphate kinase C-terminal domain; Region: PP_kinase_C; pfam13090
936154004898	Catalytic domain of phospholipase D superfamily proteins; Region: PLDc_SF; cl15239
936154004899	putative active site [active]
936154004900	catalytic site [active]
936154004901	Catalytic C-terminal domain, second repeat, of uncharacterized prokaryotic polyphosphate kinases; Region: PLDc_PPK1_C2_unchar; cd09169
936154004902	putative domain interface [polypeptide binding]; other site
936154004903	putative active site [active]
936154004904	catalytic site [active]
936154004905	Polypeptide or peptide deformylase; a family of metalloenzymes that catalyzes the removal of the N-terminal formyl group in a growing polypeptide chain following translation initiation during protein synthesis in prokaryotes. These enzymes utilize Fe(II)...; Region: Pep_deformylase; cd00487
936154004906	active site
936154004907	catalytic residues [active]
936154004908	metal binding site [ion binding]; metal-binding site
936154004909	Flavodoxin-like fold; Region: Flavodoxin_2; cl00438
936154004910	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
936154004911	Nitroreductase-like family 4.  A subfamily of the nitroreductase family containing uncharacterized proteins that are similar to nitroreductase. Nitroreductase catalyzes the reduction of nitroaromatic compounds such as nitrotoluenes, nitrofurans and...; Region: Nitroreductase_4; cd02140
936154004912	dimer interface [polypeptide binding]; other site
936154004913	FMN binding site [chemical binding]; other site
936154004914	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
936154004915	MarR family; Region: MarR; pfam01047
936154004916	DNA polymerase III PolC; Validated; Region: polC; PRK00448
936154004917	DNA polymerase III polC-type N-terminus; Region: DNA_pol3_alph_N; pfam11490
936154004918	polC_OBF: A subfamily of OB folds corresponding to the N-terminal OB-fold nucleic acid binding domain of Bacillus subtilis type C replicative DNA polymerase III alpha subunit (polC). Replication in B. subtilis and Staphylococcus aureus requires two...; Region: polC_OBF; cd04484
936154004919	generic binding surface II; other site
936154004920	generic binding surface I; other site
936154004921	Polymerase and Histidinol Phosphatase domain; Region: PHP; cl17102
936154004922	active site
936154004923	DEDDh 3'-5' exonuclease domain family; Region: DEDDh; cd06127
936154004924	active site
936154004925	catalytic site [active]
936154004926	substrate binding site [chemical binding]; other site
936154004927	Polymerase and Histidinol Phosphatase domain of alpha-subunit of bacterial polymerase III at PolC gene; Region: PHP_PolIIIA_POLC; cd07435
936154004928	Protein of unknown function (DUF975); Region: DUF975; pfam06161
936154004929	prolyl-tRNA synthetase; Provisional; Region: PRK09194
936154004930	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
936154004931	motif 1; other site
936154004932	dimer interface [polypeptide binding]; other site
936154004933	active site
936154004934	motif 2; other site
936154004935	INS is an amino acid-editing domain inserted (INS) into the bacterial class II prolyl-tRNA synthetase (ProRS) however, this CD is not exclusively bacterial. It is also found at the N-terminus of the eukaryotic/archaea-like ProRS's of yeasts and...; Region: ProRS-INS; cd04334
936154004936	putative deacylase active site [active]
936154004937	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
936154004938	active site
936154004939	motif 3; other site
936154004940	ProRS Prolyl-anticodon binding domain, short version found predominantly in bacteria. ProRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding; Region: ProRS_anticodon_short; cd00861
936154004941	anticodon binding site; other site
936154004942	RseP-like Site-2 proteases (S2P), zinc metalloproteases (MEROPS family M50A), cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. In Escherichia coli, the S2P homolog...; Region: S2P-M50_PDZ_RseP-like; cd06163
936154004943	active site
936154004944	Site-2 protease (S2P) class of zinc metalloproteases (MEROPS family M50) cleaves transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. Members of this family use proteolytic...; Region: S2P-M50; cl10020
936154004945	PDZ domain of bacterial and plant zinc metalloprotases, presumably membrane-associated or integral membrane proteases, which may be involved in signalling and regulatory mechanisms. May be responsible for substrate recognition and/or binding, as most PDZ...; Region: PDZ_metalloprotease; cd00989
936154004946	protein binding site [polypeptide binding]; other site
936154004947	CDP-diglyceride synthetase [Lipid metabolism]; Region: CdsA; COG0575
936154004948	Cytidylyltransferase family; Region: CTP_transf_1; pfam01148
936154004949	undecaprenyl pyrophosphate synthase; Provisional; Region: PRK14830
936154004950	Undecaprenyl pyrophosphate synthase [Lipid metabolism]; Region: UppS; COG0020
936154004951	catalytic residue [active]
936154004952	putative FPP diphosphate  binding site; other site
936154004953	putative FPP binding hydrophobic cleft; other site
936154004954	dimer interface [polypeptide binding]; other site
936154004955	putative IPP diphosphate binding site; other site
936154004956	preprotein translocase subunit YajC; Validated; Region: yajC; PRK06531
936154004957	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
936154004958	catalytic residues [active]
936154004959	UDP-glucose 4-epimerase [Cell envelope biogenesis, outer membrane]; Region: GalE; COG1087
936154004960	UDP-glucose 4 epimerase, subgroup 1, extended (e) SDRs; Region: UDP_G4E_1_SDR_e; cd05247
936154004961	NAD binding site [chemical binding]; other site
936154004962	homodimer interface [polypeptide binding]; other site
936154004963	active site
936154004964	substrate binding site [chemical binding]; other site
936154004965	galactose-1-phosphate uridylyltransferase; Provisional; Region: PRK05270
936154004966	Galactose-1-phosphate uridyl transferase, N-terminal domain; Region: GalP_UDP_transf; pfam01087
936154004967	Galactose-1-phosphate uridyl transferase, C-terminal domain; Region: GalP_UDP_tr_C; pfam02744
936154004968	galactokinase; Provisional; Region: PRK05322
936154004969	Galactokinase galactose-binding signature; Region: GalKase_gal_bdg; pfam10509
936154004970	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
936154004971	GHMP kinases C terminal; Region: GHMP_kinases_C; pfam08544
936154004972	DNA-binding transcriptional repressor EbgR; Provisional; Region: PRK10339
936154004973	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
936154004974	DNA binding site [nucleotide binding]
936154004975	Ligand-binding domain of DNA transcription repressor GalR which is one of two regulatory proteins involved in galactose transport and metabolism; Region: PBP1_GalR; cd01544
936154004976	putative dimerization interface [polypeptide binding]; other site
936154004977	putative ligand binding site [chemical binding]; other site
936154004978	Maltose O-acetyltransferase (MAT) and Galactoside O-acetyltransferase (GAT): MAT and GAT catalyze the CoA-dependent acetylation of the 6-hydroxyl group of their respective sugar substrates. MAT acetylates maltose and glucose exclusively at the C6...; Region: LbH_MAT_GAT; cd03357
936154004979	trimer interface [polypeptide binding]; other site
936154004980	active site
936154004981	substrate binding site [chemical binding]; other site
936154004982	CoA binding site [chemical binding]; other site
936154004983	alpha,alpha-phosphotrehalase; Region: trehalose_treC; TIGR02403
936154004984	Alpha amylase catalytic domain found in Sucrose isomerases, oligo-1,6-glucosidase (also called isomaltase; sucrase-isomaltase; alpha-limit dextrinase), dextran glucosidase (also called glucan 1,6-alpha-glucosidase), and related proteins; Region: AmyAc_SI_OligoGlu_DGase; cd11333
936154004985	Ca binding site [ion binding]; other site
936154004986	active site
936154004987	catalytic site [active]
936154004988	Domain of unknown function (DUF3459); Region: DUF3459; pfam11941
936154004989	glycerol-3-phosphate transporter ATP-binding subunit; Provisional; Region: ugpC; PRK11650
936154004990	The N-terminal ATPase domain of the maltose transporter, MalK; Region: ABC_MalK_N; cd03301
936154004991	Walker A/P-loop; other site
936154004992	ATP binding site [chemical binding]; other site
936154004993	Q-loop/lid; other site
936154004994	ABC transporter signature motif; other site
936154004995	Walker B; other site
936154004996	D-loop; other site
936154004997	H-loop/switch region; other site
936154004998	TOBE domain; Region: TOBE_2; pfam08402
936154004999	Regulator of polyketide synthase expression [Signal transduction mechanisms / Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG2508
936154005000	PucR C-terminal helix-turn-helix domain; Region: HTH_30; pfam13556
936154005001	Alpha amylase catalytic domain family; Region: AmyAc_family; cl07893
936154005002	D-Tyrosyl-tRNAtyr deacylases; a class of tRNA-dependent hydrolases which are capable of hydrolyzing the ester bond of D-Tyrosyl-tRNA reducing the level of cellular D-Tyrosine while recycling the peptidyl-tRNA; found in bacteria and in eukaryotes but not...; Region: Dtyr_deacylase; cd00563
936154005003	putative active site [active]
936154005004	dimerization interface [polypeptide binding]; other site
936154005005	putative tRNAtyr binding site [nucleotide binding]; other site
936154005006	Guanosine polyphosphate pyrophosphohydrolases/synthetases [Signal transduction mechanisms / Transcription]; Region: SpoT; COG0317
936154005007	HD domain; Region: HD_4; pfam13328
936154005008	Nucleotidyltransferase (NT) domain of RelA- and SpoT-like ppGpp synthetases and hydrolases; Region: NT_Rel-Spo_like; cd05399
936154005009	synthetase active site [active]
936154005010	NTP binding site [chemical binding]; other site
936154005011	metal binding site [ion binding]; metal-binding site
936154005012	TGS_RelA_SpoT: The RelA (SpoT) protein, also referred to as ppGpp hydrolase/synthetase, is a ribosome-associated protein that is activated during amino acid starvation and thought to mediate the stringent response. RelA contains a TGS domain, named after...; Region: TGS_RelA_SpoT; cd01668
936154005013	ACT  domain found C-terminal of the RelA/SpoT domains; Region: ACT_RelA-SpoT; cd04876
936154005014	flavoprotein NrdI; Provisional; Region: PRK02551
936154005015	Cellulase M and related proteins [Carbohydrate transport and metabolism]; Region: FrvX; COG1363
936154005016	M42 Peptidase, Endoglucanase-like subfamily; Region: M42_glucanase_like; cd05657
936154005017	putative oligomer interface [polypeptide binding]; other site
936154005018	putative active site [active]
936154005019	metal binding site [ion binding]; metal-binding site
936154005020	Streptococcus agalactiae RgfB, part of a putative two component signal transduction system, and related proteins; Region: RgfB-like; cd09079
936154005021	putative catalytic site [active]
936154005022	putative metal binding site [ion binding]; other site
936154005023	putative phosphate binding site [ion binding]; other site
936154005024	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
936154005025	PTS system, IIBC component; Region: PTS-II-BC-unk1; TIGR02003
936154005026	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
936154005027	active site turn [active]
936154005028	phosphorylation site [posttranslational modification]
936154005029	Phosphotransferase system IIA components [Carbohydrate transport and metabolism]; Region: NagE; COG2190
936154005030	HPr interaction site; other site
936154005031	glycerol kinase (GK) interaction site [polypeptide binding]; other site
936154005032	active site
936154005033	phosphorylation site [posttranslational modification]
936154005034	Transcriptional regulators [Transcription]; Region: PurR; COG1609
936154005035	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
936154005036	DNA binding site [nucleotide binding]
936154005037	domain linker motif; other site
936154005038	Type 1 periplasmic binding fold superfamily; Region: Periplasmic_Binding_Protein_Type_1; cl10011
936154005039	Helix-turn-helix domain; Region: HTH_20; pfam12840
936154005040	dimerization interface [polypeptide binding]; other site
936154005041	putative DNA binding site [nucleotide binding]; other site
936154005042	putative Zn2+ binding site [ion binding]; other site
936154005043	H+ Antiporter protein; Region: 2A0121; TIGR00900
936154005044	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1385
936154005045	RNA methyltransferase, RsmE family; Region: TIGR00046
936154005046	Ribosomal protein L11 methyltransferase (PrmA); Region: PrmA; pfam06325
936154005047	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
936154005048	S-adenosylmethionine binding site [chemical binding]; other site
936154005049	Protein of unknown function (DUF3013); Region: DUF3013; pfam11217
936154005050	Transposase; Region: HTH_Tnp_1; pfam01527
936154005051	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
936154005052	putative transposase OrfB; Reviewed; Region: PHA02517
936154005053	HTH-like domain; Region: HTH_21; pfam13276
936154005054	Integrase core domain; Region: rve; pfam00665
936154005055	Integrase core domain; Region: rve_3; pfam13683
936154005056	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
936154005057	DNA-binding site [nucleotide binding]; DNA binding site
936154005058	RNA-binding motif; other site
936154005059	Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis]; Region: RimL; COG1670
936154005060	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
936154005061	Coenzyme A binding pocket [chemical binding]; other site
936154005062	recombination factor protein RarA; Reviewed; Region: PRK13342
936154005063	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
936154005064	Walker A motif; other site
936154005065	ATP binding site [chemical binding]; other site
936154005066	Walker B motif; other site
936154005067	arginine finger; other site
936154005068	MgsA AAA+ ATPase C terminal; Region: MgsA_C; pfam12002
936154005069	PTS system mannose/fructose/sorbose family IID component; Region: EIID-AGA; pfam03613
936154005070	PTS system sorbose-specific iic component; Region: EII-Sor; cl01506
936154005071	PTS_IIB, PTS system, Mannose/sorbose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_man; cl00021
936154005072	active site
936154005073	phosphorylation site [posttranslational modification]
936154005074	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cl00025
936154005075	active pocket/dimerization site; other site
936154005076	active site
936154005077	phosphorylation site [posttranslational modification]
936154005078	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
936154005079	Bacterial extracellular solute-binding protein; Region: SBP_bac_8; pfam13416
936154005080	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
936154005081	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
936154005082	active site
936154005083	phosphorylation site [posttranslational modification]
936154005084	intermolecular recognition site; other site
936154005085	dimerization interface [polypeptide binding]; other site
936154005086	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
936154005087	dimerization interface [polypeptide binding]; other site
936154005088	DNA binding residues [nucleotide binding]
936154005089	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: COG4585
936154005090	Histidine kinase; Region: HisKA_3; pfam07730
936154005091	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Region: HATPase_c; pfam02518
936154005092	ATP binding site [chemical binding]; other site
936154005093	Mg2+ binding site [ion binding]; other site
936154005094	G-X-G motif; other site
936154005095	Periplasmic sugar-binding domain of active transport systems that are members of the type I periplasmic binding protein (PBP1) superfamily; Region: PBP1_ABC_sugar_binding_like; cd01536
936154005096	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: RbsB; COG1879
936154005097	ligand binding site [chemical binding]; other site
936154005098	haloacid dehalogenase-like hydrolase; Region: Hydrolase_3; pfam08282
936154005099	trehalose-6-phosphate phosphatase; Provisional; Region: PRK10187; cl17105
936154005100	Transcriptional regulators [Transcription]; Region: RpiR; COG1737
936154005101	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
936154005102	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
936154005103	putative active site [active]
936154005104	L-sorbose-1-phosphate reductase; Region: sorbose_phosphate_red; cd08238
936154005105	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
936154005106	putative NAD(P) binding site [chemical binding]; other site
936154005107	catalytic Zn binding site [ion binding]; other site
936154005108	PTS system mannose/fructose/sorbose family IID component; Region: EIID-AGA; cl01507
936154005109	PTS system mannose-specific transporter subunit IIC; Provisional; Region: PRK15065
936154005110	PTS_IIB, PTS system, Mannose/sorbose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_man; cd00001
936154005111	active site
936154005112	phosphorylation site [posttranslational modification]
936154005113	sorbitol-6-phosphate 2-dehydrogenase; Provisional; Region: PRK06171
936154005114	classical (c) SDRs; Region: SDR_c; cd05233
936154005115	NAD(P) binding site [chemical binding]; other site
936154005116	active site
936154005117	Transcriptional regulator, contains sigma factor-related N-terminal domain [Transcription]; Region: DeoR; COG2390
936154005118	Homeodomain-like domain; Region: HTH_23; pfam13384
936154005119	Putative sugar-binding domain; Region: Sugar-bind; pfam04198
936154005120	2-hydroxycarboxylate transporter family; Region: 2HCT; pfam03390
936154005121	malate dehydrogenase; Provisional; Region: PRK13529
936154005122	Malic enzyme, N-terminal domain; Region: malic; pfam00390
936154005123	NAD(P) binding domain of malic enzyme (ME), subgroup 1; Region: NAD_bind_1_malic_enz; cd05312
936154005124	NAD(P) binding site [chemical binding]; other site
936154005125	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
936154005126	Putative protein-S-isoprenylcysteine methyltransferase [Posttranslational modification, protein turnover, chaperones]; Region: STE14; COG2020
936154005127	heavy metal translocating P-type ATPase; Region: ATPase-IB_hvy; TIGR01525
936154005128	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
936154005129	Soluble P-type ATPase [General function prediction only]; Region: COG4087
936154005130	Helix-Turn-Helix DNA binding domain of the BmrR transcription regulator; Region: HTH_BmrR; cd01107
936154005131	MerR HTH family regulatory protein; Region: MerR_1; pfam13411
936154005132	DNA binding residues [nucleotide binding]
936154005133	drug binding residues [chemical binding]; other site
936154005134	dimer interface [polypeptide binding]; other site
936154005135	Protein of unknown function (DUF2812); Region: DUF2812; pfam11193
936154005136	Alkyladenine DNA glycosylase catalyzes the first step in base excision repair; Region: AAG; cd00540
936154005137	active site
936154005138	DNA binding site [nucleotide binding]
936154005139	Possible lysine decarboxylase; Region: Lysine_decarbox; cl00695
936154005140	Hydrolases of the alpha/beta superfamily [General function prediction only]; Region: COG1073
936154005141	Predicted transcriptional regulators [Transcription]; Region: SoxR; COG0789
936154005142	Helix-Turn-Helix DNA binding domain of the MerR-like transcription regulators YyaN and YraB; Region: HTH_YyaN; cd01109
936154005143	DNA binding residues [nucleotide binding]
936154005144	putative dimer interface [polypeptide binding]; other site
936154005145	Peptidase family C39 mostly contains bacteriocin-processing endopeptidases from bacteria. The cysteine peptidases in family C39 cleave the "double-glycine" leader peptides from the precursors of various bacteriocins (mostly non-lantibiotic); Region: Peptidase_C39_like; cl00296
936154005146	putative active site [active]
936154005147	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
936154005148	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
936154005149	Walker A/P-loop; other site
936154005150	ATP binding site [chemical binding]; other site
936154005151	Q-loop/lid; other site
936154005152	ABC transporter signature motif; other site
936154005153	Walker B; other site
936154005154	D-loop; other site
936154005155	H-loop/switch region; other site
936154005156	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
936154005157	Walker A/P-loop; other site
936154005158	ATP binding site [chemical binding]; other site
936154005159	ABC transporter; Region: ABC_tran; pfam00005
936154005160	Q-loop/lid; other site
936154005161	ABC transporter signature motif; other site
936154005162	Walker B; other site
936154005163	D-loop; other site
936154005164	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4529
936154005165	FAD-NAD(P)-binding; Region: NAD_binding_9; pfam13454
936154005166	Alpha/beta hydrolase family; Region: Abhydrolase_5; pfam12695
936154005167	BAAT / Acyl-CoA thioester hydrolase C terminal; Region: BAAT_C; pfam08840
936154005168	YbaK-like.  The YbaK family of deacylase domains includes the INS amino acid-editing domain of  the bacterial class II prolyl tRNA synthetase (ProRS), and it's trans-acting homologs, YbaK, ProX, and PrdX. The primary function of INS is to hydrolyze...; Region: YbaK_like; cl00022
936154005169	putative deacylase active site [active]
936154005170	EamA-like transporter family; Region: EamA; pfam00892
936154005171	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
936154005172	EamA-like transporter family; Region: EamA; pfam00892
936154005173	Cof subfamily of IIB subfamily of haloacid dehalogenase superfamily; Region: Cof-subfamily; TIGR00099
936154005174	CAAX protease self-immunity; Region: Abi; pfam02517
936154005175	Microcin C7 self-immunity protein determines resistance to exogenous microcin C7; Region: Peptidase_S66_mccF_like; cd07062
936154005176	putative dimer interface [polypeptide binding]; other site
936154005177	catalytic triad [active]
936154005178	Phosphatidylglycerophosphatase A; a bacterial membrane-associated enzyme involved in lipid metabolism; Region: PgpA; cd06971
936154005179	tetramer interfaces [polypeptide binding]; other site
936154005180	binuclear metal-binding site [ion binding]; other site
936154005181	Alkaline phosphatase [Inorganic ion transport and metabolism]; Region: PhoA; COG1785
936154005182	Alkaline phosphatase homologues; alkaline phosphatases are non-specific phosphomonoesterases that catalyze the hydrolysis reaction via a phosphoseryl intermediate to produce inorganic phosphate and the corresponding alcohol, optimally at high pH; Region: alkPPc; cl15837
936154005183	dimer interface [polypeptide binding]; other site
936154005184	active site
936154005185	Alkaline phosphatase homologues; alkaline phosphatases are non-specific phosphomonoesterases that catalyze the hydrolysis reaction via a phosphoseryl intermediate to produce inorganic phosphate and the corresponding alcohol, optimally at high pH; Region: alkPPc; cl15837
936154005186	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
936154005187	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
936154005188	ABC-type Na+ efflux pump, permease component [Energy production and conversion / Inorganic ion transport and metabolism]; Region: NatB; COG1668
936154005189	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
936154005190	ABC-2 type transporter; Region: ABC2_membrane; pfam01061
936154005191	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
936154005192	ABC transporter, ATP-binding subunit, PQQ-dependent alcohol dehydrogenase system; Region: PQQ_ABC_ATP; TIGR03864
936154005193	Walker A/P-loop; other site
936154005194	ATP binding site [chemical binding]; other site
936154005195	Q-loop/lid; other site
936154005196	ABC transporter signature motif; other site
936154005197	Walker B; other site
936154005198	D-loop; other site
936154005199	H-loop/switch region; other site
936154005200	glycerol-3-phosphate transporter ATP-binding subunit; Provisional; Region: ugpC; PRK11650
936154005201	The N-terminal ATPase domain of the maltose transporter, MalK; Region: ABC_MalK_N; cd03301
936154005202	Walker A/P-loop; other site
936154005203	ATP binding site [chemical binding]; other site
936154005204	Q-loop/lid; other site
936154005205	ABC transporter signature motif; other site
936154005206	Walker B; other site
936154005207	D-loop; other site
936154005208	H-loop/switch region; other site
936154005209	TOBE domain; Region: TOBE_2; pfam08402
936154005210	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
936154005211	dimer interface [polypeptide binding]; other site
936154005212	conserved gate region; other site
936154005213	putative PBP binding loops; other site
936154005214	ABC-ATPase subunit interface; other site
936154005215	Transaldolase-like fructose-6-phosphate aldolases (FSA) found in bacteria and archaea; Region: Transaldolase_FSA; cd00956
936154005216	active site
936154005217	intersubunit interactions; other site
936154005218	catalytic residue [active]
936154005219	Pyruvate-formate lyase [Energy production and conversion]; Region: PflD; COG1882
936154005220	Pyruvate formate lyase 2 and related enzymes; Region: PFL2_DhaB_BssA; cd01677
936154005221	dimer interface [polypeptide binding]; other site
936154005222	active site
936154005223	glycine loop; other site
936154005224	YjgF, YER057c, and UK114 belong to a large family of proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no...; Region: YjgF_YER057c_UK114_family; cd00448
936154005225	homotrimer interaction site [polypeptide binding]; other site
936154005226	putative active site [active]
936154005227	YjgF, YER057c, and UK114 belong to a large family of proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no...; Region: YjgF_YER057c_UK114_family; cd00448
936154005228	homotrimer interaction site [polypeptide binding]; other site
936154005229	putative active site [active]
936154005230	YjgF, YER057c, and UK114 belong to a large family of proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no...; Region: YjgF_YER057c_UK114_family; cd00448
936154005231	homotrimer interaction site [polypeptide binding]; other site
936154005232	putative active site [active]
936154005233	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; cl17531
936154005234	glycyl-radical enzyme activating protein family; Region: PFLE_PFLC; TIGR02494
936154005235	Uncharacterized protein conserved in bacteria (DUF2200); Region: DUF2200; cl02047
936154005236	Adenylosuccinate synthetase (AdSS) catalyzes the first step in the de novo biosynthesis of AMP. IMP and L-aspartate are conjugated in a two-step reaction accompanied by the hydrolysis of GTP to GDP in the presence of Mg2+. In the first step, the...; Region: AdSS; cd03108
936154005237	Adenylosuccinate synthetase; Region: Adenylsucc_synt; smart00788
936154005238	GDP-binding site [chemical binding]; other site
936154005239	ACT binding site; other site
936154005240	IMP binding site; other site
936154005241	Uncharacterized protein involved in tellurite resistance [Inorganic ion transport and metabolism]; Region: TelA; COG3853
936154005242	bifunctional glutamate--cysteine ligase/glutathione synthetase; Provisional; Region: PRK02471
936154005243	Glutamate-cysteine ligase; Region: Glu_cys_ligase; cl17352
936154005244	ATP-grasp domain; Region: ATP-grasp_4; cl17255
936154005245	Arabidopsis phospholipase-like protein (PEARLI 4); Region: PEARLI-4; pfam05278
936154005246	M protein trans-acting positive regulator (MGA) HTH domain; Region: HTH_Mga; pfam08280
936154005247	Mga helix-turn-helix domain; Region: Mga; pfam05043
936154005248	M protein trans-acting positive regulator (MGA) PRD domain; Region: PRD_Mga; pfam08270
936154005249	Hsp33-like chaperonin; Reviewed; Region: hslO; PRK00114
936154005250	Heat shock protein 33 (Hsp33):  Cytosolic protein that acts as a molecular chaperone under oxidative conditions.  In normal (reducing) cytosolic conditions, four conserved Cys residues are coordinated by a Zn ion. Under oxidative stress (such as heat...; Region: Hsp33; cd00498
936154005251	dimerization interface [polypeptide binding]; other site
936154005252	domain crossover interface; other site
936154005253	redox-dependent activation switch; other site
936154005254	putative TIM-barrel protein, nifR3 family; Region: nifR3_yhdG; TIGR00737
936154005255	Dihydrouridine synthase-like (DUS-like) FMN-binding domain. Members of this family catalyze the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also...; Region: DUS_like_FMN; cd02801
936154005256	FMN binding site [chemical binding]; other site
936154005257	active site
936154005258	catalytic residues [active]
936154005259	substrate binding site [chemical binding]; other site
936154005260	Deoxynucleoside kinases [Nucleotide transport and metabolism]; Region: COG1428
936154005261	Deoxyribonucleoside kinase (dNK) catalyzes the phosphorylation of deoxyribonucleosides to yield corresponding monophosphates (dNMPs). This family consists of various deoxynucleoside kinases including deoxyribo- cytidine (EC 2.7.1.74), guanosine (EC 2.7.1; Region: dNK; cd01673
936154005262	Substrate-binding site [chemical binding]; other site
936154005263	Substrate specificity [chemical binding]; other site
936154005264	ABC-type uncharacterized transport system, ATPase component [General function prediction only]; Region: PhnK; COG1101
936154005265	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
936154005266	Walker A/P-loop; other site
936154005267	ATP binding site [chemical binding]; other site
936154005268	Q-loop/lid; other site
936154005269	ABC transporter signature motif; other site
936154005270	Walker B; other site
936154005271	D-loop; other site
936154005272	H-loop/switch region; other site
936154005273	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
936154005274	Transmembrane subunit (TM) of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which are involved in the uptake of branched-chain amino acids (AAs), as well as TMs of transporters involved in the uptake of...; Region: TM_PBP1_branched-chain-AA_like; cd06574
936154005275	TM-ABC transporter signature motif; other site
936154005276	Type I periplasmic ligand-binding domain of uncharacterized ABC-type transport systems that are predicted to be involved in the uptake of amino acids, peptides, or inorganic ions; Region: PBP1_ABC_uncharacterized_transporter; cd06325
936154005277	zinc binding site [ion binding]; other site
936154005278	putative ligand binding site [chemical binding]; other site
936154005279	Single-stranded DNA-binding protein [DNA replication, recombination, and repair]; Region: Ssb; COG0629
936154005280	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
936154005281	dimer interface [polypeptide binding]; other site
936154005282	ssDNA binding site [nucleotide binding]; other site
936154005283	tetramer (dimer of dimers) interface [polypeptide binding]; other site
936154005284	tRNA-binding-domain-containing prokaryotic phenylalanly tRNA synthetase (PheRS) beta chain.  PheRS aminoacylate phenylalanine transfer RNAs (tRNAphe). PheRSs belong structurally to class II aminoacyl tRNA synthetases (aaRSs) but, as they aminoacylate...; Region: tRNA_bind_bactPheRS; cd02796
936154005285	putative tRNA-binding site [nucleotide binding]; other site
936154005286	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
936154005287	catalytic residues [active]
936154005288	Cellulase M and related proteins [Carbohydrate transport and metabolism]; Region: FrvX; COG1363
936154005289	glutamyl aminopeptidase; Region: glu_aminopep; TIGR03107
936154005290	pyrroline-5-carboxylate reductase; Reviewed; Region: PRK11880
936154005291	NADP oxidoreductase coenzyme F420-dependent; Region: F420_oxidored; cl17232
936154005292	CAAX protease self-immunity; Region: Abi; pfam02517
936154005293	acetate kinase A/propionate kinase 2; Reviewed; Region: PRK00180
936154005294	propionate/acetate kinase; Provisional; Region: PRK12379
936154005295	Adenine-specific DNA methylase [DNA replication, recombination, and repair]; Region: COG0827
936154005296	Methyltransferase domain; Region: Methyltransf_26; pfam13659
936154005297	Competence protein ComGC [Intracellular trafficking and secretion]; Region: ComGC; COG4537
936154005298	Bacteriophage peptidoglycan hydrolase; Region: Amidase_5; pfam05382
936154005299	Bacterial SH3 domain; Region: SH3_3; cl17532
936154005300	Holin family; Region: Phage_holin_4; pfam05105
936154005301	Protein of unknown function (DUF1366); Region: DUF1366; pfam07104
936154005302	Siphovirus protein of unknown function (DUF859); Region: DUF859; pfam05895
936154005303	Phage tail protein; Region: Sipho_tail; pfam05709
936154005304	Phage tail protein; Region: Sipho_tail; cl17486
936154005305	tape measure domain; Region: tape_meas_nterm; TIGR02675
936154005306	Phage-related protein [Function unknown]; Region: COG5412
936154005307	Bacteriophage Gp15 protein; Region: Phage_Gp15; pfam06854
936154005308	Minor capsid protein from bacteriophage; Region: Minor_capsid_3; pfam12691
936154005309	Minor capsid protein; Region: Minor_capsid_2; pfam11114
936154005310	Phage minor structural protein GP20; Region: Phage_GP20; pfam06810
936154005311	Phage minor capsid protein 2; Region: Phage_min_cap2; pfam06152
936154005312	phage portal protein, putative, A118 family; Region: A118_put_portal; TIGR01542
936154005313	Phage portal protein, SPP1 Gp6-like; Region: Phage_prot_Gp6; pfam05133
936154005314	Phage terminase large subunit; Region: Terminase_3; cl12054
936154005315	Stage 0 sporulation protein J (antagonist of Soj) containing ParB-like nuclease domain [Transcription]; Region: Spo0J; COG1475
936154005316	ParB-like nuclease domain; Region: ParBc; pfam02195
936154005317	Domain of unknown function (DUF4417); Region: DUF4417; pfam14386
936154005318	Protein of unknown function (DUF1642); Region: DUF1642; pfam07852
936154005319	Single-stranded DNA-binding protein [DNA replication, recombination, and repair]; Region: Ssb; COG0629
936154005320	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
936154005321	dimer interface [polypeptide binding]; other site
936154005322	ssDNA binding site [nucleotide binding]; other site
936154005323	tetramer (dimer of dimers) interface [polypeptide binding]; other site
936154005324	Protein of unknown function (DUF1351); Region: DUF1351; pfam07083
936154005325	N-terminal phage replisome organiser (Phage_rep_org_N); Region: Phage_rep_org_N; pfam09681
936154005326	Replication initiation and membrane attachment; Region: DnaB_2; pfam07261
936154005327	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
936154005328	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
936154005329	non-specific DNA binding site [nucleotide binding]; other site
936154005330	salt bridge; other site
936154005331	sequence-specific DNA binding site [nucleotide binding]; other site
936154005332	Predicted transcriptional regulator [Transcription]; Region: COG2932
936154005333	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
936154005334	Catalytic site [active]
936154005335	Recombinase zinc beta ribbon domain; Region: Zn_ribbon_recom; pfam13408
936154005336	Type II secretory pathway, component PulF [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PulF; COG1459
936154005337	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
936154005338	Protein of unknown function (DUF1033); Region: DUF1033; pfam06279
936154005339	DNA-directed RNA polymerase subunit beta'; Provisional; Region: PRK00566
936154005340	RNA polymerase Rpb1, domain 1; Region: RNA_pol_Rpb1_1; pfam04997
936154005341	RNA polymerase I subunit A N-terminus; Region: RPOLA_N; smart00663
936154005342	RNA polymerase Rpb1, domain 3; Region: RNA_pol_Rpb1_3; pfam04983
936154005343	RNA polymerase Rpb1, domain 4; Region: RNA_pol_Rpb1_4; pfam05000
936154005344	Largest subunit (beta') of Bacterial DNA-dependent RNA polymerase (RNAP), C-terminal domain; Region: RNAP_beta'_C; cd02655
936154005345	Rpb1 (beta') - Rpb6 (omega) interaction site [polypeptide binding]; other site
936154005346	G-loop; other site
936154005347	Largest subunit (beta') of Bacterial DNA-dependent RNA polymerase (RNAP), C-terminal domain; Region: RNAP_beta'_C; cd02655
936154005348	DNA binding site [nucleotide binding]
936154005349	Rpb1 (beta') - Rpb2 (beta) interaction site [polypeptide binding]; other site
936154005350	DNA-directed RNA polymerase subunit beta; Reviewed; Region: rpoB; PRK00405
936154005351	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cl17585
936154005352	RNA polymerase Rpb2, domain 2; Region: RNA_pol_Rpb2_2; pfam04561
936154005353	RNA polymerase Rpb2, domain 2; Region: RNA_pol_Rpb2_2; pfam04561
936154005354	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cd00653
936154005355	RPB1 interaction site [polypeptide binding]; other site
936154005356	RPB10 interaction site [polypeptide binding]; other site
936154005357	RPB11 interaction site [polypeptide binding]; other site
936154005358	RPB3 interaction site [polypeptide binding]; other site
936154005359	RPB12 interaction site [polypeptide binding]; other site
936154005360	Membrane carboxypeptidase (penicillin-binding protein) [Cell envelope biogenesis, outer membrane]; Region: MrcB; COG0744
936154005361	Transglycosylase; Region: Transgly; pfam00912
936154005362	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
936154005363	tyrosyl-tRNA synthetase; Validated; Region: PRK05912
936154005364	catalytic core domain of tyrosinyl-tRNA synthetase; Region: TyrRS_core; cd00805
936154005365	active site
936154005366	HIGH motif; other site
936154005367	dimer interface [polypeptide binding]; other site
936154005368	KMSKS motif; other site
936154005369	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
936154005370	RNA binding surface [nucleotide binding]; other site
936154005371	ABC-type Mn2+/Zn2+ transport systems, permease components [Inorganic ion transport and metabolism]; Region: ZnuB; COG1108
936154005372	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
936154005373	ABC-ATPase subunit  interface; other site
936154005374	dimer interface [polypeptide binding]; other site
936154005375	putative PBP binding regions; other site
936154005376	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
936154005377	ATP-binding cassette domain of the metal-type transporters; Region: ABC_Metallic_Cations; cd03235
936154005378	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
936154005379	putative DNA binding site [nucleotide binding]; other site
936154005380	putative Zn2+ binding site [ion binding]; other site
936154005381	4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Provisional; Region: ipk; PRK00128
936154005382	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
936154005383	GHMP kinases C terminal; Region: GHMP_kinases_C; pfam08544
936154005384	Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; Region: IspA; COG0142
936154005385	Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685
936154005386	substrate binding pocket [chemical binding]; other site
936154005387	chain length determination region; other site
936154005388	substrate-Mg2+ binding site; other site
936154005389	catalytic residues [active]
936154005390	aspartate-rich region 1; other site
936154005391	active site lid residues [active]
936154005392	aspartate-rich region 2; other site
936154005393	ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease components [Energy production and conversion / Posttranslational modification, protein turnover, chaperones]; Region: CydC; COG4987
936154005394	ATP-binding cassette domain of CydCD, subfamily C; Region: ABCC_cytochrome_bd; cd03247
936154005395	Walker A/P-loop; other site
936154005396	ATP binding site [chemical binding]; other site
936154005397	Q-loop/lid; other site
936154005398	ABC transporter signature motif; other site
936154005399	Walker B; other site
936154005400	D-loop; other site
936154005401	H-loop/switch region; other site
936154005402	potential frameshift: common BLAST hit: gi|25011824|ref|NP_736219.1| ABC transporter ATP-binding protein
936154005403	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
936154005404	Walker A/P-loop; other site
936154005405	ATP binding site [chemical binding]; other site
936154005406	ABC transporter; Region: ABC_tran; pfam00005
936154005407	Q-loop/lid; other site
936154005408	ABC transporter signature motif; other site
936154005409	Walker B; other site
936154005410	D-loop; other site
936154005411	H-loop/switch region; other site
936154005412	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
936154005413	cytochrome d ubiquinol oxidase subunit 2; Provisional; Region: PRK15003; cl12219
936154005414	Cytochrome oxidase subunit II; Region: Cyto_ox_2; pfam02322
936154005415	Bacterial Cytochrome Ubiquinol Oxidase; Region: Bac_Ubq_Cox; pfam01654
936154005416	NADH dehydrogenase, FAD-containing subunit [Energy production and conversion]; Region: Ndh; COG1252
936154005417	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
936154005418	1,4-dihydroxy-2-naphthoate octaprenyltransferase; Validated; Region: PRK06080
936154005419	UbiA prenyltransferase family; Region: UbiA; pfam01040
936154005420	formaldehyde dehydrogenase (FDH)-like; Region: FDH_like_ADH3; cd08287
936154005421	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
936154005422	catalytic Zn binding site [ion binding]; other site
936154005423	NAD(P) binding site [chemical binding]; other site
936154005424	structural Zn binding site [ion binding]; other site
936154005425	Methyltransferase domain; Region: Methyltransf_31; pfam13847
936154005426	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
936154005427	S-adenosylmethionine binding site [chemical binding]; other site
936154005428	potential frameshift: common BLAST hit: gi|146321833|ref|YP_001201544.1| subtilisin-like serine protease
936154005429	Peptidase domain in the S8 and S53 families; Region: Peptidases_S8_S53; cl10459
936154005430	catalytic residues [active]
936154005431	Fn3-like domain (DUF1034); Region: DUF1034; pfam06280
936154005432	Peptidase S8 family domain in Streptococcal C5a peptidases; Region: Peptidases_S8_C5a_Peptidase; cd07475
936154005433	putative active site [active]
936154005434	catalytic triad [active]
936154005435	Pyridoxamine 5'-phosphate oxidase; Region: Pyridox_oxidase; pfam01243
936154005436	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
936154005437	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
936154005438	Walker A/P-loop; other site
936154005439	ATP binding site [chemical binding]; other site
936154005440	Q-loop/lid; other site
936154005441	ABC transporter signature motif; other site
936154005442	Walker B; other site
936154005443	D-loop; other site
936154005444	H-loop/switch region; other site
936154005445	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
936154005446	ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms]; Region: SalY; COG0577
936154005447	FtsX-like permease family; Region: FtsX; pfam02687
936154005448	Peptidase propeptide and YPEB domain; Region: PepSY; pfam03413
936154005449	Peptidase propeptide and YPEB domain; Region: PepSY; pfam03413
936154005450	Anion permease ArsB/NhaD.  These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life.  A typical anion permease contains 8-13 transmembrane helices...; Region: ArsB_NhaD_permease; cl17221
936154005451	transmembrane helices; other site
936154005452	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
936154005453	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4627
936154005454	Helix-turn-helix domain; Region: HTH_18; pfam12833
936154005455	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3708
936154005456	C-terminal processing peptidase family S41; Region: Peptidase_S41; cl02526
936154005457	Active site serine [active]
936154005458	integrase; Provisional; Region: int; PHA02601
936154005459	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
936154005460	DNA polymerase III, epsilon subunit and related 3'-5' exonucleases [DNA replication, recombination, and repair]; Region: DnaQ; COG0847
936154005461	DEDDh 3'-5' exonuclease domain family; Region: DEDDh; cd06127
936154005462	active site
936154005463	catalytic site [active]
936154005464	substrate binding site [chemical binding]; other site
936154005465	HTH domain; Region: HTH_11; cl17392
936154005466	HI0933-like protein; Region: HI0933_like; pfam03486
936154005467	Chromate resistance exported protein; Region: Chrome_Resist; cl01744
936154005468	30S ribosomal protein S14; Reviewed; Region: rpsN; PRK08881
936154005469	UGMP family protein; Validated; Region: PRK09604
936154005470	Inactive homolog of metal-dependent proteases, putative molecular chaperone [Posttranslational modification, protein turnover, chaperones]; Region: COG1214; cl17884
936154005471	Carbamoyltransferase; Region: CmcH_NodU; pfam02543
936154005472	ribosomal-protein-alanine acetyltransferase; Region: rimI; TIGR01575
936154005473	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
936154005474	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
936154005475	Coenzyme A binding pocket [chemical binding]; other site
936154005476	tRNA threonylcarbamoyl adenosine modification protein YeaZ; Region: T6A_YeaZ; TIGR03725
936154005477	Glycoprotease family; Region: Peptidase_M22; pfam00814
936154005478	mRNA degradation ribonucleases J1/J2 (metallo-beta-lactamase superfamily) [Translation, ribosomal structure and biogenesis; Replication, recombination and repair]; Region: COG0595
936154005479	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
936154005480	RNA-metabolising metallo-beta-lactamase; Region: RMMBL; pfam07521
936154005481	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppF; COG1124
936154005482	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
936154005483	Walker A/P-loop; other site
936154005484	ATP binding site [chemical binding]; other site
936154005485	Q-loop/lid; other site
936154005486	ABC transporter signature motif; other site
936154005487	Walker B; other site
936154005488	D-loop; other site
936154005489	H-loop/switch region; other site
936154005490	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; pfam08352
936154005491	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppD; COG0444
936154005492	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
936154005493	Walker A/P-loop; other site
936154005494	ATP binding site [chemical binding]; other site
936154005495	Q-loop/lid; other site
936154005496	ABC transporter signature motif; other site
936154005497	Walker B; other site
936154005498	D-loop; other site
936154005499	H-loop/switch region; other site
936154005500	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
936154005501	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppC; COG1173
936154005502	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
936154005503	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
936154005504	putative PBP binding loops; other site
936154005505	dimer interface [polypeptide binding]; other site
936154005506	ABC-ATPase subunit interface; other site
936154005507	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
936154005508	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
936154005509	dimer interface [polypeptide binding]; other site
936154005510	conserved gate region; other site
936154005511	putative PBP binding loops; other site
936154005512	ABC-ATPase subunit interface; other site
936154005513	ABC-type oligopeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: OppA; COG4166
936154005514	The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold; Region: PBP2_OppA; cd08504
936154005515	peptide binding site [polypeptide binding]; other site
936154005516	Glutamine synthetase [Amino acid transport and metabolism]; Region: GlnA; COG0174
936154005517	Glutamine synthetase, beta-Grasp domain; Region: Gln-synt_N; pfam03951
936154005518	Glutamine synthetase, catalytic domain; Region: Gln-synt_C; pfam00120
936154005519	Helix-Turn-Helix DNA binding domain of GlnR-like transcription regulators; Region: HTH_GlnR-like; cd01105
936154005520	MerR HTH family regulatory protein; Region: MerR_1; pfam13411
936154005521	DNA binding residues [nucleotide binding]
936154005522	putative dimer interface [polypeptide binding]; other site
936154005523	Predicted membrane protein [Function unknown]; Region: COG4129
936154005524	Phosphoglycerate kinase (PGK) is a monomeric enzyme which catalyzes the transfer of the high-energy phosphate group of 1,3-bisphosphoglycerate to ADP, forming ATP and 3-phosphoglycerate. This reaction represents the first of the two substrate-level...; Region: Phosphoglycerate_kinase; cl00198
936154005525	ADP binding site [chemical binding]; other site
936154005526	catalytic site [active]
936154005527	Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase [Carbohydrate transport and metabolism]; Region: GapA; COG0057
936154005528	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Region: Gp_dh_N; smart00846
936154005529	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; pfam02800
936154005530	elongation factor G; Reviewed; Region: PRK00007
936154005531	Elongation factor G (EF-G) family involved in both the elongation and ribosome recycling phases of protein synthesis; Region: EF-G; cd01886
936154005532	G1 box; other site
936154005533	putative GEF interaction site [polypeptide binding]; other site
936154005534	GTP/Mg2+ binding site [chemical binding]; other site
936154005535	Switch I region; other site
936154005536	G2 box; other site
936154005537	G3 box; other site
936154005538	Switch II region; other site
936154005539	G4 box; other site
936154005540	G5 box; other site
936154005541	EFG_mtEFG_II: this subfamily represents the domain II of elongation factor G (EF-G) in bacteria and, the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2)_like proteins found in eukaryotes. During the process of peptide synthesis...; Region: EFG_mtEFG_II; cd04088
936154005542	EFG_mtEFG1_IV: domains similar to domain IV of the bacterial translational elongation factor (EF) EF-G. Included in this group is a domain of mitochondrial Elongation factor G1 (mtEFG1) proteins homologous to domain IV of EF-G. Eukaryotic cells harbor 2...; Region: EFG_mtEFG1_IV; cd01434
936154005543	EFG_mtEFG_C: domains similar to the C-terminal domain of the bacterial translational elongation factor (EF) EF-G.  Included in this group is the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2) proteins. Eukaryotic cells harbor 2...; Region: EFG_mtEFG_C; cd03713
936154005544	30S ribosomal protein S7; Validated; Region: PRK05302
936154005545	S12-like family, 30S ribosomal protein S12 subfamily; S12 is located at the interface of the large and small ribosomal subunits of prokaryotes, chloroplasts and mitochondria, where it plays an important role in both tRNA and ribosomal subunit...; Region: Ribosomal_S12; cd03368
936154005546	S17 interaction site [polypeptide binding]; other site
936154005547	S8 interaction site; other site
936154005548	16S rRNA interaction site [nucleotide binding]; other site
936154005549	streptomycin interaction site [chemical binding]; other site
936154005550	23S rRNA interaction site [nucleotide binding]; other site
936154005551	aminoacyl-tRNA interaction site (A-site) [nucleotide binding]; other site
936154005552	SEC10/PgrA surface exclusion domain; Region: Surf_Exclu_PgrA; TIGR04320
936154005553	pur operon repressor; Provisional; Region: PRK09213
936154005554	Bacterial purine repressor, N-terminal; Region: PuR_N; pfam09182
936154005555	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
936154005556	active site
936154005557	Predicted HD-superfamily hydrolase [General function prediction only]; Region: COG3481
936154005558	YhaM_OBF_like: A subfamily of OB folds similar to that found in Bacillus subtilis YhaM and Staphylococcus aureus cmp-binding factor-1 (SaCBF1). Both these proteins are 3'-to-5'exoribonucleases. YhaM requires Mn2+ or Co2+ for activity and is...; Region: YhaM_OBF_like; cd04492
936154005559	generic binding surface II; other site
936154005560	generic binding surface I; other site
936154005561	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
936154005562	Zn2+ binding site [ion binding]; other site
936154005563	Mg2+ binding site [ion binding]; other site
936154005564	Predicted nuclease of restriction endonuclease-like fold, RmuC family [General function prediction only]; Region: COG1322
936154005565	RmuC family; Region: RmuC; pfam02646
936154005566	Pentose-5-phosphate-3-epimerase [Carbohydrate transport and metabolism]; Region: Rpe; COG0036
936154005567	Ribulose-5-phosphate 3-epimerase (RPE). This enzyme catalyses the interconversion of D-ribulose 5-phosphate (Ru5P) into D-xylulose 5-phosphate, as part of the Calvin cycle (reductive pentose phosphate pathway) in chloroplasts and in the oxidative pentose...; Region: RPE; cd00429
936154005568	substrate binding site [chemical binding]; other site
936154005569	hexamer interface [polypeptide binding]; other site
936154005570	metal binding site [ion binding]; metal-binding site
936154005571	GTPase RsgA; Reviewed; Region: PRK00098
936154005572	S1_YloQ_GTPase: YloQ GTase family (also known as YjeQ and CpgA), S1-like RNA-binding domain. Proteins in the YloQ GTase family bind the ribosome and have GTPase activity. The precise role of this family is unknown. The protein structure is composed of...; Region: S1_YloQ_GTPase; cd04466
936154005573	RNA binding site [nucleotide binding]; other site
936154005574	homodimer interface [polypeptide binding]; other site
936154005575	Ribosomal interacting GTPase YjeQ/EngC, a circularly permuted subfamily of the Ras GTPases; Region: YjeQ_EngC; cd01854
936154005576	GTPase/Zn-binding domain interface [polypeptide binding]; other site
936154005577	GTP/Mg2+ binding site [chemical binding]; other site
936154005578	G4 box; other site
936154005579	G1 box; other site
936154005580	Switch I region; other site
936154005581	G2 box; other site
936154005582	G3 box; other site
936154005583	Switch II region; other site
936154005584	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
936154005585	Major Facilitator Superfamily; Region: MFS_1; pfam07690
936154005586	putative substrate translocation pore; other site
936154005587	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
936154005588	16S ribosomal RNA methyltransferase KsgA/Dim1 family protein; Reviewed; Region: ksgA; PRK00274
936154005589	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
936154005590	S-adenosylmethionine binding site [chemical binding]; other site
936154005591	Domain of unknown function (DUF4093); Region: DUF4093; pfam13331
936154005592	TatD like proteins;  E.coli TatD is a cytoplasmic protein, shown to have magnesium dependent DNase activity; Region: TatD_DNAse; cd01310
936154005593	Predicted metal-dependent hydrolases with the TIM-barrel fold [General function prediction only]; Region: COG1099
936154005594	active site
936154005595	putative PTS system  transporter subunits IIBC; Provisional; Region: PRK11404
936154005596	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
936154005597	active site
936154005598	P-loop; other site
936154005599	phosphorylation site [posttranslational modification]
936154005600	Phosphotransferase system, fructose-specific IIC component [Carbohydrate transport and metabolism]; Region: FruA; COG1299
936154005601	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
936154005602	active site
936154005603	phosphorylation site [posttranslational modification]
936154005604	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
936154005605	Transcriptional regulators [Transcription]; Region: RpiR; COG1737
936154005606	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
936154005607	putative active site [active]
936154005608	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
936154005609	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
936154005610	nucleotide binding site [chemical binding]; other site
936154005611	Dihydrodipicolinate synthase/N-acetylneuraminate lyase [Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: DapA; COG0329
936154005612	Class I aldolases; Region: Aldolase_Class_I; cl17187
936154005613	catalytic residue [active]
936154005614	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
936154005615	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
936154005616	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
936154005617	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
936154005618	dimer interface [polypeptide binding]; other site
936154005619	conserved gate region; other site
936154005620	putative PBP binding loops; other site
936154005621	ABC-ATPase subunit interface; other site
936154005622	ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177
936154005623	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
936154005624	dimer interface [polypeptide binding]; other site
936154005625	conserved gate region; other site
936154005626	putative PBP binding loops; other site
936154005627	ABC-ATPase subunit interface; other site
936154005628	N-acetylmannosamine-6-phosphate epimerase (NanE) converts N-acetylmannosamine-6-phosphate to N-acetylglucosamine-6-phosphate. This reaction is part of the pathway that allows the usage of sialic acid as a carbohydrate source. Sialic acids are a family of...; Region: NanE; cd04729
936154005629	N-acetylmannosamine-6-phosphate 2-epimerase; Provisional; Region: PRK01130
936154005630	putative active site cavity [active]
936154005631	50S ribosomal protein L34; Reviewed; Region: rpmH; PRK00399
936154005632	Response regulator of the LytR/AlgR family [Transcription / Signal transduction mechanisms]; Region: LytT; COG3279
936154005633	LytTr DNA-binding domain; Region: LytTR; smart00850
936154005634	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
936154005635	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
936154005636	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
936154005637	Walker A/P-loop; other site
936154005638	ATP binding site [chemical binding]; other site
936154005639	Q-loop/lid; other site
936154005640	ABC transporter signature motif; other site
936154005641	Walker B; other site
936154005642	D-loop; other site
936154005643	H-loop/switch region; other site
936154005644	Predicted RNA-binding protein [General function prediction only]; Region: Jag; COG1847
936154005645	jag_K homology RNA-binding domain. The KH domain is found in proteins homologous to the Bacillus subtilis protein Jag, which is associated with SpoIIIJ and is necessary for the third stage of sporulation.  The KH motif is a beta-alpha-alpha-beta-beta...; Region: jag_KH; cd02414
936154005646	G-X-X-G motif; other site
936154005647	R3H domain found in proteins homologous to Bacillus subtilus Jag, which is associated with SpoIIIJ. SpoIIIJ is necessary for the third stage of sporulation. The name of the R3H domain comes from the characteristic spacing of the most conserved arginine...; Region: R3H_jag; cd02644
936154005648	RxxxH motif; other site
936154005649	Preprotein translocase subunit YidC [Intracellular trafficking and secretion]; Region: YidC; COG0706
936154005650	membrane protein insertase, YidC/Oxa1 family, C-terminal domain; Region: yidC_oxa1_cterm; TIGR03592
936154005651	ribonuclease P; Reviewed; Region: rnpA; PRK00499
936154005652	argininosuccinate lyase; Provisional; Region: PRK00855
936154005653	Argininosuccinate lyase (argininosuccinase, ASAL); Region: Argininosuccinate_lyase; cd01359
936154005654	active sites [active]
936154005655	tetramer interface [polypeptide binding]; other site
936154005656	argininosuccinate synthase; Provisional; Region: PRK13820
936154005657	Argininosuccinate synthase. The Argininosuccinate synthase is a urea cycle enzyme that catalyzes the penultimate step in arginine biosynthesis: the ATP-dependent ligation of citrulline to aspartate to form argininosuccinate, AMP and pyrophosphate .  In...; Region: Argininosuccinate_Synthase; cd01999
936154005658	ANP binding site [chemical binding]; other site
936154005659	Substrate Binding Site II [chemical binding]; other site
936154005660	Substrate Binding Site I [chemical binding]; other site
936154005661	Response regulator of the LytR/AlgR family [Transcription / Signal transduction mechanisms]; Region: LytT; COG3279
936154005662	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
936154005663	active site
936154005664	phosphorylation site [posttranslational modification]
936154005665	intermolecular recognition site; other site
936154005666	dimerization interface [polypeptide binding]; other site
936154005667	LytTr DNA-binding domain; Region: LytTR; pfam04397
936154005668	Predicted signal transduction protein with a C-terminal ATPase domain [Signal transduction mechanisms]; Region: COG2972
936154005669	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Region: HATPase_c; pfam02518
936154005670	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Region: HATPase_c; pfam02518
936154005671	ATP binding site [chemical binding]; other site
936154005672	Mg2+ binding site [ion binding]; other site
936154005673	G-X-G motif; other site
936154005674	glutamyl-tRNA synthetase; Reviewed; Region: gltX; PRK01406
936154005675	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
936154005676	active site
936154005677	HIGH motif; other site
936154005678	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
936154005679	active site
936154005680	KMSKS motif; other site
936154005681	Uncharacterized conserved protein [Function unknown]; Region: COG2013
936154005682	Carbonic anhydrases (CA) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism in which the nucleophilic attack of a zinc-bound hydroxide ion on carbon dioxide is followed by the regeneration of an...; Region: beta_CA_cladeD; cd03379
936154005683	active site clefts [active]
936154005684	zinc binding site [ion binding]; other site
936154005685	dimer interface [polypeptide binding]; other site
936154005686	DNA repair protein RadA; Provisional; Region: PRK11823
936154005687	Sms (bacterial radA) DNA repair protein. This protein is not related to archael radA any more than is to other RecA-like NTPases. Sms has a role in recombination and recombinational repair and is responsible for the stabilization or processing of...; Region: Sms; cd01121
936154005688	Walker A motif/ATP binding site; other site
936154005689	ATP binding site [chemical binding]; other site
936154005690	Walker B motif; other site
936154005691	Subunit ChlI of Mg-chelatase; Region: ChlI; pfam13541
936154005692	Trimeric dUTP diphosphatases; Region: trimeric_dUTPase; cd07557
936154005693	trimer interface [polypeptide binding]; other site
936154005694	active site
936154005695	Protein of unknown function (DUF454); Region: DUF454; cl01063
936154005696	Predicted flavoprotein [General function prediction only]; Region: COG0431
936154005697	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
936154005698	Predicted flavoprotein [General function prediction only]; Region: COG0431
936154005699	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
936154005700	PAS domain; Region: PAS_10; pfam13596
936154005701	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
936154005702	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
936154005703	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
936154005704	Walker A/P-loop; other site
936154005705	ATP binding site [chemical binding]; other site
936154005706	Q-loop/lid; other site
936154005707	ABC transporter signature motif; other site
936154005708	Walker B; other site
936154005709	D-loop; other site
936154005710	H-loop/switch region; other site
936154005711	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
936154005712	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
936154005713	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
936154005714	Walker A/P-loop; other site
936154005715	ATP binding site [chemical binding]; other site
936154005716	Q-loop/lid; other site
936154005717	ABC transporter signature motif; other site
936154005718	Walker B; other site
936154005719	D-loop; other site
936154005720	H-loop/switch region; other site
936154005721	MarR family; Region: MarR_2; pfam12802
936154005722	NAD(P)H-dependent glycerol-3-phosphate dehydrogenase; Validated; Region: gpsA; PRK00094
936154005723	NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; Region: NAD_Gly3P_dh_N; pfam01210
936154005724	NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus; Region: NAD_Gly3P_dh_C; pfam07479
936154005725	Prokaryotic UGPase catalyses the synthesis of UDP-glucose; Region: UGPase_prokaryotic; cd02541
936154005726	dTDP-glucose pyrophosphorylase [Cell envelope biogenesis, outer membrane]; Region: RfbA; COG1209
936154005727	active site
936154005728	tetramer interface; other site
936154005729	Membrane associated serine protease [Amino acid transport and metabolism]; Region: COG0705
936154005730	5-formyltetrahydrofolate cyclo-ligase family; Region: 5-FTHF_cyc-lig; pfam01812
936154005731	5,10-methenyltetrahydrofolate synthetase; Region: MTHFS_bact; TIGR02727
936154005732	Na+-driven multidrug efflux pump [Defense mechanisms]; Region: NorM; COG0534
936154005733	Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Bacillus subtilis yoeA; Region: MATE_yoeA_like; cd13138
936154005734	UDP-glucose 6-dehydrogenase; Provisional; Region: PRK15057
936154005735	UDP-glucose/GDP-mannose dehydrogenase family, central domain; Region: UDPG_MGDP_dh; pfam00984
936154005736	UDP binding domain; Region: UDPG_MGDP_dh_C; smart00984
936154005737	chitooligosaccharide synthase NodC; Region: nodulat_NodC; TIGR04242
936154005738	CESA_like is  the cellulose synthase superfamily; Region: CESA_like; cd06423
936154005739	Glycosyl transferase family group 2; Region: Glyco_trans_2_3; pfam13632
936154005740	DXD motif; other site
936154005741	M20 Peptidase Aminoacyclase-1 YkuR-like proteins, including YkuR and Ama/HipO/HyuC proteins; Region: M20_Acy1_YkuR_like; cd05670
936154005742	Metal-dependent amidase/aminoacylase/carboxypeptidase [General function prediction only]; Region: AbgB; COG1473
936154005743	metal binding site [ion binding]; metal-binding site
936154005744	putative dimer interface [polypeptide binding]; other site
936154005745	Tetrahydrodipicolinate succinyltransferase N-terminal; Region: DapH_N; pfam08503
936154005746	2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase; Region: DapD_Ac; TIGR03532
936154005747	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cl00160
936154005748	putative trimer interface [polypeptide binding]; other site
936154005749	putative CoA binding site [chemical binding]; other site
936154005750	PTS system glucitol/sorbitol-specific IIA component; Region: PTSIIA_gutA; pfam03829
936154005751	PTS system, glucitol/sorbitol-specific, IIBC component; Region: EIIBC-GUT; TIGR00825
936154005752	Sorbitol phosphotransferase enzyme II N-terminus; Region: EIIBC-GUT_N; pfam03612
936154005753	Sorbitol phosphotransferase enzyme II C-terminus; Region: EIIBC-GUT_C; pfam07663
936154005754	PTS system enzyme II sorbitol-specific factor; Region: EII-GUT; pfam03608
936154005755	Glucitol operon activator protein (GutM); Region: GutM; pfam06923
936154005756	Transcriptional antiterminator [Transcription]; Region: BglG; COG3711
936154005757	HTH domain; Region: HTH_11; pfam08279
936154005758	PRD domain; Region: PRD; pfam00874
936154005759	PTS_IIB_bgl_like: the PTS (phosphotransferase system) IIB domain of a family of sensory systems composed of a membrane-bound sugar-sensor (similar to BglF) and a transcription antiterminator (similar to BglG) which regulate expression of genes involved...; Region: PTS_IIB_bgl_like; cd05568
936154005760	active site
936154005761	P-loop; other site
936154005762	phosphorylation site [posttranslational modification]
936154005763	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
936154005764	active site
936154005765	phosphorylation site [posttranslational modification]
936154005766	sorbitol-6-phosphate 2-dehydrogenase; Provisional; Region: PRK06171
936154005767	classical (c) SDRs; Region: SDR_c; cd05233
936154005768	NAD(P) binding site [chemical binding]; other site
936154005769	active site
936154005770	glucose-6-phosphate isomerase; Provisional; Region: pgi; PRK14097
936154005771	Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the first SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_1; cd05015
936154005772	active site
936154005773	dimer interface [polypeptide binding]; other site
936154005774	Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the second SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_2; cd05016
936154005775	dimer interface [polypeptide binding]; other site
936154005776	active site
936154005777	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
936154005778	non-specific DNA binding site [nucleotide binding]; other site
936154005779	salt bridge; other site
936154005780	sequence-specific DNA binding site [nucleotide binding]; other site
936154005781	Predicted transcriptional regulator [Transcription]; Region: COG2932
936154005782	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
936154005783	Catalytic site [active]
936154005784	Nucleoside deaminases include adenosine, guanine and cytosine deaminases. These enzymes are Zn dependent and catalyze the deamination of nucleosides. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a...; Region: nucleoside_deaminase; cd01285
936154005785	nucleoside/Zn binding site; other site
936154005786	dimer interface [polypeptide binding]; other site
936154005787	catalytic motif [active]
936154005788	Metal-dependent hydrolases of the beta-lactamase superfamily III [General function prediction only]; Region: ElaC; COG1234
936154005789	Predicted Zn-dependent hydrolases of the beta-lactamase fold [General function prediction only]; Region: COG2220
936154005790	BioY family; Region: BioY; pfam02632
936154005791	queuine tRNA-ribosyltransferase; Provisional; Region: tgt; PRK00112
936154005792	Queuine/archaeosine tRNA-ribosyltransferase [Translation, ribosomal structure and biogenesis]; Region: Tgt; COG0343
936154005793	Protein of unknown function (DUF975); Region: DUF975; cl10504
936154005794	Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators; Region: Fur_like; cd07153
936154005795	metal binding site 2 [ion binding]; metal-binding site
936154005796	putative DNA binding helix; other site
936154005797	metal binding site 1 [ion binding]; metal-binding site
936154005798	dimer interface [polypeptide binding]; other site
936154005799	structural Zn2+ binding site [ion binding]; other site
936154005800	Predicted CoA-binding protein [General function prediction only]; Region: COG1832
936154005801	DNA polymerase I; Provisional; Region: PRK05755
936154005802	PIN domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: PIN_53EXO; cd09859
936154005803	active site
936154005804	metal binding site 1 [ion binding]; metal-binding site
936154005805	putative 5' ssDNA interaction site; other site
936154005806	metal binding site 3; metal-binding site
936154005807	metal binding site 2 [ion binding]; metal-binding site
936154005808	H3TH domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: H3TH_53EXO; cd09898
936154005809	putative DNA binding site [nucleotide binding]; other site
936154005810	putative metal binding site [ion binding]; other site
936154005811	inactive DEDDy 3'-5' exonuclease domain of Bacillus stearothermophilus DNA polymerase I and similar family-A DNA polymerases; Region: DNA_polA_I_Bacillus_like_exo; cd06140
936154005812	Polymerase I functions primarily to fill DNA gaps that arise during DNA repair, recombination and replication; Region: DNA_pol_A_pol_I_C; cd08637
936154005813	active site
936154005814	DNA binding site [nucleotide binding]
936154005815	catalytic site [active]
936154005816	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
936154005817	dimer interface [polypeptide binding]; other site
936154005818	conserved gate region; other site
936154005819	putative PBP binding loops; other site
936154005820	ABC-ATPase subunit interface; other site
936154005821	ABC-type proline/glycine betaine transport systems, periplasmic components [Amino acid transport and metabolism]; Region: ProX; cl17891
936154005822	Substrate binding domain of ABC-type glycine betaine transport system; Region: OpuAC; pfam04069
936154005823	ABC-type proline/glycine betaine transport system, ATPase component [Amino acid transport and metabolism]; Region: ProV; COG4175
936154005824	ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; Region: ABC_Pro_Gly_Betaine; cd03294
936154005825	Walker A/P-loop; other site
936154005826	ATP binding site [chemical binding]; other site
936154005827	Q-loop/lid; other site
936154005828	ABC transporter signature motif; other site
936154005829	Walker B; other site
936154005830	D-loop; other site
936154005831	H-loop/switch region; other site
936154005832	The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called...; Region: CBS_pair; cl15354
936154005833	Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase [Lipid metabolism / General function prediction only]; Region: LCB5; COG1597
936154005834	Diacylglycerol kinase catalytic domain; Region: DAGK_cat; pfam00781
936154005835	Metallo-beta-lactamase superfamily; Region: Lactamase_B; cl00446
936154005836	Predicted Zn-dependent hydrolases of the beta-lactamase fold [General function prediction only]; Region: COG2220
936154005837	Transcriptional antiterminator [Transcription]; Region: BglG; COG3711
936154005838	HTH domain; Region: HTH_11; pfam08279
936154005839	PRD domain; Region: PRD; pfam00874
936154005840	PTS_IIB_bgl_like: the PTS (phosphotransferase system) IIB domain of a family of sensory systems composed of a membrane-bound sugar-sensor (similar to BglF) and a transcription antiterminator (similar to BglG) which regulate expression of genes involved...; Region: PTS_IIB_bgl_like; cd05568
936154005841	active site
936154005842	P-loop; other site
936154005843	phosphorylation site [posttranslational modification]
936154005844	L-ribulose-5-phosphate 4-epimerase; Provisional; Region: araD; PRK13145
936154005845	L-ribulose-5-phosphate 4-epimerase; Reviewed; Region: araD; PRK08193
936154005846	intersubunit interface [polypeptide binding]; other site
936154005847	active site
936154005848	Zn2+ binding site [ion binding]; other site
936154005849	putative L-xylulose 5-phosphate 3-epimerase; Reviewed; Region: PRK13210
936154005850	AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cd00019
936154005851	AP (apurinic/apyrimidinic) site pocket; other site
936154005852	DNA interaction; other site
936154005853	Metal-binding active site; metal-binding site
936154005854	3-Keto-L-gulonate 6-phosphate decarboxylase (KGPDC) and D-arabino-3-hexulose-6-phosphate synthase (HPS). KGPDC catalyzes the formation of L-xylulose 5-phosphate and carbon dioxide from 3-keto-L-gulonate 6-phosphate as part of the anaerobic pathway for...; Region: KGPDC_HPS; cd04726
936154005855	active site
936154005856	dimer interface [polypeptide binding]; other site
936154005857	magnesium binding site [ion binding]; other site
936154005858	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
936154005859	active site
936154005860	phosphorylation site [posttranslational modification]
936154005861	PTS system ascorbate-specific transporter subunit IIC; Reviewed; Region: PRK12997
936154005862	Glycerate kinase [Carbohydrate transport and metabolism]; Region: COG1929
936154005863	leucyl-tRNA synthetase; Validated; Region: leuS; PRK00390
936154005864	catalytic core domain of leucyl-tRNA synthetases; Region: LeuRS_core; cd00812
936154005865	HIGH motif; other site
936154005866	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
936154005867	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
936154005868	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
936154005869	active site
936154005870	KMSKS motif; other site
936154005871	Anticodon-binding domain of bacterial and eukaryotic mitochondrial leucyl tRNA synthetases; Region: Anticodon_Ia_Leu_BEm; cd07958
936154005872	tRNA binding surface [nucleotide binding]; other site
936154005873	transcription antitermination protein NusG; Validated; Region: nusG; PRK05609
936154005874	Bacterial N-Utilization Substance G (NusG) N-terminal (NGN) domain, subgroup 1; Region: NGN_Bact_1; cd09891
936154005875	putative homodimer interface [polypeptide binding]; other site
936154005876	NusG contains an NGN domain at its N-terminus and KOW motif at its C-terminus; Region: KOW_NusG; cd06091
936154005877	heterodimer interface [polypeptide binding]; other site
936154005878	homodimer interface [polypeptide binding]; other site
936154005879	50S ribosomal protein L33; Validated; Region: rpmG; PRK00504
936154005880	Transglycosylase; Region: Transgly; pfam00912
936154005881	penicillin-binding protein, 1A family; Region: PBP_1a_fam; TIGR02074
936154005882	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
936154005883	YjgF, YER057c, and UK114 belong to a large family of proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no...; Region: YjgF_YER057c_UK114_family; cd00448
936154005884	homotrimer interaction site [polypeptide binding]; other site
936154005885	putative active site [active]
936154005886	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
936154005887	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
936154005888	active site
936154005889	Dipeptidase [Amino acid transport and metabolism]; Region: PepD; COG4690
936154005890	G5 domain; Region: G5; pfam07501
936154005891	chaperonin GroEL; Reviewed; Region: groEL; PRK12849
936154005892	GroEL_like type I chaperonin. Chaperonins are involved in productive folding of proteins. They share a common general morphology, a double toroid of 2 stacked rings, each composed of 7-9 subunits. The symmetry of type I is seven-fold and they are found...; Region: GroEL; cd03344
936154005893	ring oligomerisation interface [polypeptide binding]; other site
936154005894	ATP/Mg binding site [chemical binding]; other site
936154005895	stacking interactions; other site
936154005896	hinge regions; other site
936154005897	Chaperonin 10 Kd subunit (cpn10 or GroES); Cpn10 cooperates with chaperonin 60 (cpn60 or GroEL), an ATPase, to assist the folding and assembly of proteins and is found in eubacterial cytosol, as well as in the matrix of mitochondria and chloroplasts. It...; Region: cpn10; cd00320
936154005898	oligomerisation interface [polypeptide binding]; other site
936154005899	mobile loop; other site
936154005900	roof hairpin; other site
936154005901	ATP-binding subunits of Clp protease and DnaK/DnaJ chaperones [Posttranslational modification, protein turnover, chaperones]; Region: clpA; COG0542
936154005902	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
936154005903	Walker A motif; other site
936154005904	ATP binding site [chemical binding]; other site
936154005905	Walker B motif; other site
936154005906	arginine finger; other site
936154005907	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
936154005908	Walker A motif; other site
936154005909	ATP binding site [chemical binding]; other site
936154005910	Walker B motif; other site
936154005911	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431
936154005912	Firmicute transcriptional repressor of class III stress genes (CtsR); Region: CtsR; pfam05848
936154005913	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
936154005914	DNA-binding site [nucleotide binding]; DNA binding site
936154005915	RNA-binding motif; other site
936154005916	NhaP-type Na+/H+ and K+/H+ antiporters [Inorganic ion transport and metabolism]; Region: NhaP; COG0025
936154005917	N-terminal domain of Sphingobium chlorophenolicum 2,6-dichloro-p-hydroquinone 1,2-dioxygenase (PcpA), and similar proteins; Region: PcpA_N_like; cd08346
936154005918	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
936154005919	Zn binding site [ion binding]; other site
936154005920	C-terminal domain of Sphingobium chlorophenolicum 2,6-dichloro-p-hydroquinone 1,2-dioxygenase (PcpA), and similar proteins; Region: PcpA_C_like; cd08347
936154005921	Zn binding site [ion binding]; other site
936154005922	C-terminal domain of Sphingobium chlorophenolicum 2,6-dichloro-p-hydroquinone 1,2-dioxygenase (PcpA), and similar proteins; Region: PcpA_C_like; cd08347
936154005923	Zn binding site [ion binding]; other site
936154005924	Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family [General function prediction only]; Region: COG1853
936154005925	Predicted esterase [General function prediction only]; Region: COG0400
936154005926	putative hydrolase; Provisional; Region: PRK11460
936154005927	DNA/RNA non-specific endonuclease; Region: Endonuclease_NS; smart00892
936154005928	DNA/RNA non-specific endonuclease; Region: Endonuclea_NS_2; cl17626
936154005929	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold; Region: Thioredoxin_like; cl00388
936154005930	alkyl hydroperoxide reductase subunit F; Provisional; Region: PRK15317
936154005931	Alkyl hydroperoxide reductase F subunit (AhpF) N-terminal domain (NTD) family, N-terminal TRX-fold subdomain; AhpF is a homodimeric flavoenzyme which catalyzes the NADH-dependent reduction of the peroxiredoxin AhpC, which in turn catalyzes the reduction...; Region: AhpF_NTD_N; cd02974
936154005932	catalytic residue [active]
936154005933	TRX-GRX-like family, Alkyl hydroperoxide reductase F subunit (AhpF) N-terminal domain (NTD) subfamily, C-terminal TRX-fold subdomain; AhpF is a homodimeric flavoenzyme which catalyzes the NADH-dependent reduction of the peroxiredoxin AhpC, which then...; Region: AhpF_NTD_C; cd03026
936154005934	catalytic residues [active]
936154005935	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
936154005936	Ribosomal protein S2 (RPS2), involved in formation of the translation initiation complex, where it might contact the messenger RNA and several components of the ribosome. It has been shown that in Escherichia coli RPS2 is essential for the binding of...; Region: RPS2; cd01425
936154005937	rRNA interaction site [nucleotide binding]; other site
936154005938	S8 interaction site; other site
936154005939	putative laminin-1 binding site; other site
936154005940	elongation factor Ts; Provisional; Region: tsf; PRK09377
936154005941	UBA/TS-N domain; Region: UBA; pfam00627
936154005942	Elongation factor TS; Region: EF_TS; pfam00889
936154005943	Predicted metalloendopeptidase [Posttranslational modification, protein turnover, chaperones]; Region: PepO; COG3590
936154005944	Peptidase family M13 includes neprilysin, endothelin-converting enzyme I; Region: M13; cd08662
936154005945	active site
936154005946	Zn binding site [ion binding]; other site
936154005947	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
936154005948	PYR/PP interface [polypeptide binding]; other site
936154005949	dimer interface [polypeptide binding]; other site
936154005950	TPP binding site [chemical binding]; other site
936154005951	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
936154005952	Thiamine pyrophosphate (TPP) family, Transketolase (TK) subfamily, TPP-binding module; TK catalyzes the transfer of a two-carbon unit from ketose phosphates to aldose phosphates. In heterotrophic organisms, TK provides a link between glycolysis and the...; Region: TPP_TK; cd02012
936154005953	TPP-binding site [chemical binding]; other site
936154005954	dimer interface [polypeptide binding]; other site
936154005955	PTS system ascorbate-specific transporter subunit IIC; Reviewed; Region: ulaA; PRK09410
936154005956	Transcriptional antiterminator [Transcription]; Region: BglG; COG3711
936154005957	PRD domain; Region: PRD; pfam00874
936154005958	PTS_IIB_bgl_like: the PTS (phosphotransferase system) IIB domain of a family of sensory systems composed of a membrane-bound sugar-sensor (similar to BglF) and a transcription antiterminator (similar to BglG) which regulate expression of genes involved...; Region: PTS_IIB_bgl_like; cd05568
936154005959	active site
936154005960	P-loop; other site
936154005961	phosphorylation site [posttranslational modification]
936154005962	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
936154005963	active site
936154005964	phosphorylation site [posttranslational modification]
936154005965	PTS_IIB_ascorbate: subunit IIB of enzyme II (EII) of the L-ascorbate-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is an L-ascorbate-specific permease with two cytoplasmic subunits (IIA and IIB) and a...; Region: PTS_IIB_ascorbate; cd05563
936154005966	active site
936154005967	P-loop; other site
936154005968	phosphorylation site [posttranslational modification]
936154005969	alpha,alpha-phosphotrehalase; Region: trehalose_treC; TIGR02403
936154005970	Alpha amylase catalytic domain found in Sucrose isomerases, oligo-1,6-glucosidase (also called isomaltase; sucrase-isomaltase; alpha-limit dextrinase), dextran glucosidase (also called glucan 1,6-alpha-glucosidase), and related proteins; Region: AmyAc_SI_OligoGlu_DGase; cd11333
936154005971	Ca binding site [ion binding]; other site
936154005972	active site
936154005973	catalytic site [active]
936154005974	PTS system, trehalose-specific IIBC component; Region: PTS-IIBC-Tre; TIGR01992
936154005975	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
936154005976	active site turn [active]
936154005977	phosphorylation site [posttranslational modification]
936154005978	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
936154005979	Phosphotransferase system IIA components [Carbohydrate transport and metabolism]; Region: NagE; COG2190
936154005980	HPr interaction site; other site
936154005981	glycerol kinase (GK) interaction site [polypeptide binding]; other site
936154005982	active site
936154005983	phosphorylation site [posttranslational modification]
936154005984	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
936154005985	DNA-binding site [nucleotide binding]; DNA binding site
936154005986	trehalose operon repressor, B. subtilis-type; Region: trehalos_R_Bsub; TIGR02404
936154005987	UTRA domain; Region: UTRA; pfam07702
936154005988	Predicted transcriptional regulators [Transcription]; Region: COG1733
936154005989	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
936154005990	dimerization interface [polypeptide binding]; other site
936154005991	putative DNA binding site [nucleotide binding]; other site
936154005992	putative Zn2+ binding site [ion binding]; other site
936154005993	Predicted ring-cleavage extradiol dioxygenase [General function prediction only]; Region: COG2514
936154005994	This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_12; cd07255
936154005995	putative metal binding site [ion binding]; other site
936154005996	hypothetical protein; Validated; Region: PRK02101
936154005997	anaerobic ribonucleoside-triphosphate reductase activating protein; Region: NrdG; TIGR02491
936154005998	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
936154005999	FeS/SAM binding site; other site
936154006000	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
936154006001	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
936154006002	Coenzyme A binding pocket [chemical binding]; other site
936154006003	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
936154006004	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
936154006005	anaerobic ribonucleoside triphosphate reductase; Provisional; Region: PRK09263
936154006006	ATP cone domain; Region: ATP-cone; pfam03477
936154006007	Class III ribonucleotide reductase; Region: RNR_III; cd01675
936154006008	effector binding site; other site
936154006009	active site
936154006010	Zn binding site [ion binding]; other site
936154006011	glycine loop; other site
936154006012	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family [Cell envelope biogenesis, outer membrane]; Region: ArnT; COG1807
936154006013	hypothetical protein; Provisional; Region: PRK13678
936154006014	Holliday junction resolvase-like protein; Reviewed; Region: PRK00109
936154006015	hypothetical protein; Provisional; Region: PRK05473
936154006016	Arsenate Reductase (ArsC) family, Spx subfamily; Spx is a unique RNA polymerase (RNAP)-binding protein present in bacilli and some mollicutes. It inhibits transcription by binding to the C-terminal domain of the alpha subunit of RNAP, disrupting complex...; Region: ArsC_Spx; cd03032
936154006017	ArsC family; Region: ArsC; pfam03960
936154006018	putative catalytic residues [active]
936154006019	thiol/disulfide switch; other site
936154006020	RecA is a  bacterial enzyme which has roles in homologous recombination, DNA repair, and the induction of the SOS response.  RecA couples ATP hydrolysis to DNA strand exchange; Region: recA; cd00983
936154006021	hexamer interface [polypeptide binding]; other site
936154006022	ATPases associated with a variety of cellular activities; Region: AAA; smart00382
936154006023	Walker A motif; other site
936154006024	ATP binding site [chemical binding]; other site
936154006025	Walker B motif; other site
936154006026	Uncharacterized protein (competence- and mitomycin-induced) [General function prediction only]; Region: CinA; COG1546
936154006027	Methyladenine glycosylase; Region: Adenine_glyco; pfam03352
936154006028	Holliday junction DNA helicase RuvA; Reviewed; Region: ruvA; PRK00116
936154006029	RuvA N terminal domain; Region: RuvA_N; pfam01330
936154006030	RuvA, C-terminal domain; Region: RuvA_C; pfam07499
936154006031	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
936154006032	Major Facilitator Superfamily; Region: MFS_1; pfam07690
936154006033	putative substrate translocation pore; other site
936154006034	DNA mismatch repair protein; Reviewed; Region: mutL; PRK00095
936154006035	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
936154006036	ATP binding site [chemical binding]; other site
936154006037	Mg2+ binding site [ion binding]; other site
936154006038	G-X-G motif; other site
936154006039	MutL_Trans: transducer domain, having a ribosomal S5 domain 2-like fold, conserved in the C-terminal domain of DNA mismatch repair (MutL/MLH1/PMS2) family. This transducer domain is homologous to the second domain of the DNA gyrase B subunit, which is...; Region: MutL_Trans; cd00782
936154006040	ATP binding site [chemical binding]; other site
936154006041	MutL C terminal dimerisation domain; Region: MutL_C; pfam08676
936154006042	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
936154006043	phiLC3 phage and phage-related integrases, site-specific recombinases, DNA breaking-rejoining enzymes, C-terminal catalytic domain. This CD includes various bacterial (mainly gram positive) and phage integrases, including those similar to Lactococcus...; Region: INT_phiLC3_C; cd01189
936154006044	Int/Topo IB signature motif; other site
936154006045	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
936154006046	non-specific DNA binding site [nucleotide binding]; other site
936154006047	salt bridge; other site
936154006048	sequence-specific DNA binding site [nucleotide binding]; other site
936154006049	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cl17257
936154006050	DNA binding residues [nucleotide binding]
936154006051	Domain of unknown function (DUF4298); Region: DUF4298; pfam14131
936154006052	Host cell surface-exposed lipoprotein; Region: Lipoprotein_Ltp; pfam07553
936154006053	Host cell surface-exposed lipoprotein; Region: Lipoprotein_Ltp; pfam07553
936154006054	Host cell surface-exposed lipoprotein; Region: Lipoprotein_Ltp; pfam07553
936154006055	Cadmium resistance transporter; Region: Cad; pfam03596
936154006056	cadmium resistance transporter (or sequestration) family protein; Region: cad; TIGR00779
936154006057	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
936154006058	dimerization interface [polypeptide binding]; other site
936154006059	putative DNA binding site [nucleotide binding]; other site
936154006060	putative Zn2+ binding site [ion binding]; other site
936154006061	MutS domain I; Region: MutS_I; pfam01624
936154006062	MutS domain II; Region: MutS_II; pfam05188
936154006063	MutS domain III; Region: MutS_III; pfam05192
936154006064	Protein of unknown function (DUF964); Region: DUF964; cl01483
936154006065	Arginine repressor, DNA binding domain; Region: Arg_repressor; pfam01316
936154006066	arginine repressor; Region: argR_whole; TIGR01529
936154006067	Arginine repressor, C-terminal domain; Region: Arg_repressor_C; pfam02863
936154006068	arginyl-tRNA synthetase; Reviewed; Region: PRK12451
936154006069	Arginyl tRNA synthetase N terminal dom; Region: Arg_tRNA_synt_N; smart01016
936154006070	catalytic core domain of arginyl-tRNA synthetases; Region: ArgRS_core; cd00671
936154006071	active site
936154006072	HIGH motif; other site
936154006073	KMSK motif region; other site
936154006074	Anticodon-binding domain of arginyl tRNA synthetases; Region: Anticodon_Ia_Arg; cd07956
936154006075	tRNA binding surface [nucleotide binding]; other site
936154006076	anticodon binding site; other site
936154006077	Uncharacterized conserved protein [Function unknown]; Region: COG1284
936154006078	Uncharacterized BCR, YitT family COG1284; Region: DUF161; pfam02588
936154006079	Uncharacterized BCR, YitT family COG1284; Region: DUF161; pfam02588
936154006080	Uncharacterized protein conserved in bacteria (DUF2179); Region: DUF2179; pfam10035
936154006081	Uncharacterized conserved protein [Function unknown]; Region: COG1284
936154006082	Uncharacterized BCR, YitT family COG1284; Region: DUF161; pfam02588
936154006083	Uncharacterized protein conserved in bacteria (DUF2179); Region: DUF2179; pfam10035
936154006084	Uncharacterized conserved protein [Function unknown]; Region: COG1284
936154006085	Uncharacterized BCR, YitT family COG1284; Region: DUF161; pfam02588
936154006086	Uncharacterized BCR, YitT family COG1284; Region: DUF161; pfam02588
936154006087	Uncharacterized protein conserved in bacteria (DUF2179); Region: DUF2179; pfam10035
936154006088	aspartyl-tRNA synthetase; Validated; Region: aspS; PRK00476
936154006089	EcAspRS_like_N: N-terminal, anticodon recognition domain of the type found in Escherichia coli aspartyl-tRNA synthetase (AspRS), the human mitochondrial (mt) AspRS-2, the discriminating (D) Thermus thermophilus AspRS-1, and the nondiscriminating (ND)...; Region: EcAspRS_like_N; cd04317
936154006090	dimer interface [polypeptide binding]; other site
936154006091	anticodon binding site; other site
936154006092	Asp tRNA synthetase (aspRS) class II core domain. Class II assignment is based upon its structure and the presence of three characteristic sequence motifs. AspRS is a homodimer, which attaches a specific amino acid to the 3' OH group of ribose of...; Region: AspRS_core; cd00777
936154006093	homodimer interface [polypeptide binding]; other site
936154006094	motif 1; other site
936154006095	active site
936154006096	motif 2; other site
936154006097	GAD domain; Region: GAD; pfam02938
936154006098	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
936154006099	active site
936154006100	motif 3; other site
936154006101	histidyl-tRNA synthetase; Reviewed; Region: hisS; PRK00037
936154006102	Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core domain. HisRS is a homodimer. It is responsible for the attachment of histidine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for...; Region: HisRS-like_core; cd00773
936154006103	dimer interface [polypeptide binding]; other site
936154006104	motif 1; other site
936154006105	active site
936154006106	motif 2; other site
936154006107	motif 3; other site
936154006108	HisRS Histidyl-anticodon binding domain. HisRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: HisRS_anticodon; cd00859
936154006109	anticodon binding site; other site
936154006110	50S ribosomal protein L32; Validated; Region: rpmF; PRK01110
936154006111	50S ribosomal protein L33; Validated; Region: rpmG; PRK00595
936154006112	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
936154006113	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
936154006114	non-specific DNA binding site [nucleotide binding]; other site
936154006115	salt bridge; other site
936154006116	sequence-specific DNA binding site [nucleotide binding]; other site
936154006117	NADH pyrophosphatase, a member of the Nudix hydrolase superfamily, catalyzes the cleavage of NADH into reduced nicotinamide mononucleotide (NMNH) and AMP. Like other members of the Nudix family, it requires a divalent cation, such as Mg2+ or Mn2+, for...; Region: NADH_pyrophosphatase; cd03429
936154006118	putative NADH binding site [chemical binding]; other site
936154006119	putative active site [active]
936154006120	nudix motif; other site
936154006121	putative metal binding site [ion binding]; other site
936154006122	Predicted membrane protein [Function unknown]; Region: COG2035
936154006123	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
936154006124	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
936154006125	non-specific DNA binding site [nucleotide binding]; other site
936154006126	salt bridge; other site
936154006127	sequence-specific DNA binding site [nucleotide binding]; other site
936154006128	FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203
936154006129	GAF domain; Region: GAF_3; pfam13492
936154006130	GAF domain; Region: GAF_2; pfam13185
936154006131	GAF domain; Region: GAF_3; pfam13492
936154006132	PucR C-terminal helix-turn-helix domain; Region: HTH_30; pfam13556
936154006133	Acyl CoA:acetate/3-ketoacid CoA transferase [Lipid metabolism]; Region: COG4670
936154006134	Coenzyme A transferase; Region: CoA_trans; smart00882
936154006135	Coenzyme A transferase; Region: CoA_trans; cl17247
936154006136	Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II [Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism]; Region: CaiC; COG0318
936154006137	Bacterial Bile acid CoA ligases and similar proteins; Region: BACL_like; cd05929
936154006138	acyl-activating enzyme (AAE) consensus motif; other site
936154006139	putative AMP binding site [chemical binding]; other site
936154006140	putative active site [active]
936154006141	putative CoA binding site [chemical binding]; other site
936154006142	3-hydroxybutyryl-CoA dehydrogenase; Validated; Region: PRK05808
936154006143	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; Region: 3HCDH_N; pfam02737
936154006144	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725
936154006145	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725
936154006146	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
936154006147	3-hydroxybutyryl-CoA dehydratase; Validated; Region: PRK05809
936154006148	substrate binding site [chemical binding]; other site
936154006149	oxyanion hole (OAH) forming residues; other site
936154006150	trimer interface [polypeptide binding]; other site
936154006151	putative acyltransferase; Provisional; Region: PRK05790
936154006152	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
936154006153	dimer interface [polypeptide binding]; other site
936154006154	active site
936154006155	Acyl-CoA dehydrogenase; Region: ACAD; cl09933
936154006156	acyl-coenzyme A oxidase; Region: PLN02526
936154006157	active site
936154006158	3-hydroxyacyl-CoA dehydrogenase [Lipid metabolism]; Region: FadB; COG1250
936154006159	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; Region: 3HCDH_N; pfam02737
936154006160	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725
936154006161	Predicted transcriptional regulators [Transcription]; Region: COG1695
936154006162	Transcriptional regulator PadR-like family; Region: PadR; pfam03551
936154006163	Predicted membrane protein [Function unknown]; Region: COG4709
936154006164	Domain of unknown function (DUF4097); Region: DUF4097; pfam13349
936154006165	Domain of unknown function (DUF4098); Region: DUF4098; pfam13345
936154006166	Domain of unknown function (DUF4098); Region: DUF4098; pfam13345
936154006167	Protein of unknown function (DUF1304); Region: DUF1304; pfam06993
936154006168	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
936154006169	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
936154006170	Domain of unknown function (DUF4298); Region: DUF4298; pfam14131
936154006171	Hydrolase of X-linked nucleoside diphosphate N terminal; Region: Nudix_N; pfam12535
936154006172	Nudix hydrolase is a superfamily of enzymes found in all three kingdoms of life, and it catalyzes the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+...; Region: Nudix_Hydrolase; cl00447
936154006173	30S ribosomal protein S4; Validated; Region: rpsD; PRK05327
936154006174	Ribosomal protein S4/S9 N-terminal domain; Region: Ribosomal_S4; pfam00163
936154006175	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
936154006176	RNA binding surface [nucleotide binding]; other site
936154006177	Uncharacterized protein conserved in bacteria [Function unknown]; Region: Veg; COG4466
936154006178	replicative DNA helicase; Provisional; Region: PRK05748
936154006179	DnaB-like helicase N terminal domain; Region: DnaB; pfam00772
936154006180	DnaB helicase C terminal domain. The hexameric helicase DnaB unwinds the DNA duplex at the  chromosome replication fork. Although the mechanism by which DnaB both couples ATP hydrolysis to translocation along DNA and denatures the duplex is unknown, a...; Region: DnaB_C; cd00984
936154006181	Walker A motif; other site
936154006182	ATP binding site [chemical binding]; other site
936154006183	Walker B motif; other site
936154006184	DNA binding loops [nucleotide binding]
936154006185	50S ribosomal protein L9; Reviewed; Region: rplI; PRK00137
936154006186	Ribosomal protein L9, N-terminal domain; Region: Ribosomal_L9_N; pfam01281
936154006187	Ribosomal protein L9, C-terminal domain; Region: Ribosomal_L9_C; pfam03948
936154006188	Predicted signaling protein consisting of a modified GGDEF domain and a DHH domain [Signal transduction mechanisms]; Region: COG3887
936154006189	DHH family; Region: DHH; pfam01368
936154006190	DHHA1 domain; Region: DHHA1; pfam02272
936154006191	tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA; Validated; Region: PRK05192
936154006192	NAD(FAD)-utilizing enzyme possibly involved in translation [Translation, ribosomal structure and biogenesis]; Region: Gid; COG1206
936154006193	GidA associated domain 3; Region: GIDA_assoc_3; pfam13932
936154006194	Predicted tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain [Translation, ribosomal structure and biogenesis]; Region: TrmU; COG0482
936154006195	tRNA-specific 2-thiouridylase MnmA; Reviewed; Region: mnmA; PRK00143
936154006196	tRNA methyl transferase. This family represents tRNA(5-methylaminomethyl-2-thiouridine)-methyltransferase which is involved in the biosynthesis of the modified nucleoside 5-methylaminomethyl-2-thiouridine present in the wobble position of some tRNAs; Region: tRNA_Me_trans; cd01998
936154006197	L-serine dehydratase, iron-sulfur-dependent, beta subunit; Region: sda_beta; TIGR00719
936154006198	Serine dehydratase beta chain; Region: SDH_beta; pfam03315
936154006199	C-terminal ACT domain of the L-serine dehydratase (LSD), iron-sulfur-dependent, beta subunit; Region: ACT_LSD; cd04903
936154006200	putative L-serine binding site [chemical binding]; other site
936154006201	Serine dehydratase alpha chain; Region: SDH_alpha; cl12120
936154006202	L-serine deaminase [Amino acid transport and metabolism]; Region: SdaA; COG1760
936154006203	Predicted phosphatases [General function prediction only]; Region: Gph; COG0546
936154006204	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
936154006205	motif II; other site
936154006206	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
936154006207	N-acetyl-D-glucosamine binding site [chemical binding]; other site
936154006208	catalytic residue [active]
936154006209	ABC-type cobalt transport system, permease component CbiQ and related transporters [Inorganic ion transport and metabolism]; Region: CbiQ; COG0619
936154006210	cobalt transporter ATP-binding subunit; Provisional; Region: cbiO; PRK13649
936154006211	First domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain1; cd03225
936154006212	Walker A/P-loop; other site
936154006213	ATP binding site [chemical binding]; other site
936154006214	Q-loop/lid; other site
936154006215	ABC transporter signature motif; other site
936154006216	Walker B; other site
936154006217	D-loop; other site
936154006218	H-loop/switch region; other site
936154006219	cobalt transporter ATP-binding subunit; Provisional; Region: cbiO; PRK13650
936154006220	First domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain1; cd03225
936154006221	Walker A/P-loop; other site
936154006222	ATP binding site [chemical binding]; other site
936154006223	Q-loop/lid; other site
936154006224	ABC transporter signature motif; other site
936154006225	Walker B; other site
936154006226	D-loop; other site
936154006227	H-loop/switch region; other site
936154006228	CDP-alcohol phosphatidyltransferase; Region: CDP-OH_P_transf; cl00453
936154006229	Helix-turn-helix domain; Region: HTH_25; pfam13413
936154006230	potential frameshift: common BLAST hit: gi|71911662|ref|YP_283212.1| zinc protease
936154006231	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
936154006232	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
936154006233	Insulinase (Peptidase family M16); Region: Peptidase_M16; pfam00675
936154006234	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
936154006235	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
936154006236	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
936154006237	S4-like RNA binding protein [Replication, recombination, and repair]; Region: COG2501
936154006238	recombination protein F; Reviewed; Region: recF; PRK00064
936154006239	ATP-binding cassette domain of RecF; Region: ABC_RecF; cd03242
936154006240	Walker A/P-loop; other site
936154006241	ATP binding site [chemical binding]; other site
936154006242	Q-loop/lid; other site
936154006243	ABC transporter signature motif; other site
936154006244	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
936154006245	ABC transporter signature motif; other site
936154006246	Walker B; other site
936154006247	D-loop; other site
936154006248	H-loop/switch region; other site
936154006249	inosine 5'-monophosphate dehydrogenase; Reviewed; Region: PRK05567
936154006250	TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl17186
936154006251	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in the inosine 5' monophosphate dehydrogenase (IMPDH) protein.  IMPDH is an essential enzyme that catalyzes the first step unique to GTP synthesis, playing a...; Region: CBS_pair_IMPDH; cd04601
936154006252	IMPDH: The catalytic domain of the inosine monophosphate dehydrogenase. IMPDH catalyzes the NAD-dependent oxidation of inosine 5'-monophosphate (IMP) to xanthosine 5' monophosphate (XMP). It is a rate-limiting step in the de novo synthesis of...; Region: IMPDH; cd00381
936154006253	active site
936154006254	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
936154006255	Uncharacterized conserved protein [Function unknown]; Region: COG1284
936154006256	Uncharacterized BCR, YitT family COG1284; Region: DUF161; pfam02588
936154006257	Uncharacterized BCR, YitT family COG1284; Region: DUF161; pfam02588
936154006258	Uncharacterized protein conserved in bacteria (DUF2179); Region: DUF2179; pfam10035
936154006259	ABC transporter ATP-binding protein; Provisional; Region: PRK15064
936154006260	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
936154006261	Walker A/P-loop; other site
936154006262	ATP binding site [chemical binding]; other site
936154006263	Q-loop/lid; other site
936154006264	ABC transporter signature motif; other site
936154006265	Walker B; other site
936154006266	D-loop; other site
936154006267	H-loop/switch region; other site
936154006268	ABC transporter; Region: ABC_tran_2; pfam12848
936154006269	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
936154006270	Predicted membrane protein [Function unknown]; Region: COG4485
936154006271	rRNA large subunit methyltransferase; Provisional; Region: PRK00103
936154006272	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
936154006273	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
936154006274	protein binding site [polypeptide binding]; other site
936154006275	ParB/RepB/Spo0J family partition protein; Region: parB_part; TIGR00180
936154006276	ParB-like nuclease domain; Region: ParBc; pfam02195
936154006277	Sugar-specific transcriptional regulator TrmB; Region: TrmB; cl17775