-- dump date 20140620_083922 -- class Genbank::CDS -- table cds_note -- id note YP_002739320.1 binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication; can also affect transcription of multiple genes including itself. YP_002739321.1 binds the polymerase to DNA and acts as a sliding clamp YP_002739322.1 identified by match to protein family HMM PF06107 YP_002739323.1 translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1 YP_002739324.1 Enables the recycling of peptidyl-tRNAs produced at termination of translation YP_002739325.1 identified by match to protein family HMM PF00270; match to protein family HMM PF00271; match to protein family HMM PF02559; match to protein family HMM PF03461; match to protein family HMM PF04851; match to protein family HMM TIGR00580 YP_002739326.1 identified by match to protein family HMM PF01479 YP_002739327.1 identified by match to protein family HMM PF04977 YP_002739330.1 identified by match to protein family HMM PF01171; match to protein family HMM TIGR02432; match to protein family HMM TIGR02433 YP_002739331.1 identified by match to protein family HMM PF00156; match to protein family HMM TIGR01203 YP_002739332.1 identified by match to protein family HMM PF00004; match to protein family HMM PF01434; match to protein family HMM PF06480; match to protein family HMM TIGR01241 YP_002739333.1 identified by match to protein family HMM PF01610 YP_002739336.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002739337.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002739339.1 catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis YP_002739340.1 identified by match to protein family HMM PF00589 YP_002739341.1 identified by match to protein family HMM PF08797 YP_002739342.1 identified by match to protein family HMM PF06114 YP_002739343.1 identified by match to protein family HMM PF01381 YP_002739347.1 identified by match to protein family HMM PF02498 YP_002739351.1 identified by match to protein family HMM PF04271; match to protein family HMM TIGR01446; match to protein family HMM TIGR01714 YP_002739354.1 identified by glimmer; putative YP_002739356.1 identified by glimmer; putative YP_002739358.1 identified by match to protein family HMM PF07852 YP_002739359.1 identified by similarity to GB:AAZ82434.1; match to protein family HMM PF07852 YP_002739360.1 identified by glimmer; putative YP_002739362.1 identified by match to protein family HMM TIGR01671 YP_002739364.1 identified by match to protein family HMM PF01381 YP_002739365.1 identified by match to protein family HMM TIGR01637 YP_002739366.1 identified by match to protein family HMM PF00589 YP_002739367.1 identified by glimmer; putative YP_002739368.1 identified by match to protein family HMM PF01844 YP_002739369.1 identified by match to protein family HMM PF07360 YP_002739371.1 identified by glimmer; putative YP_002739372.1 identified by glimmer; putative YP_002739373.1 identified by match to protein family HMM PF03354 YP_002739384.1 identified by match to protein family HMM PF05017 YP_002739386.1 identified by match to protein family HMM PF02018; match to protein family HMM TIGR01665 YP_002739389.1 identified by match to protein family HMM PF05105; match to protein family HMM TIGR01593 YP_002739390.1 identified by match to protein family HMM TIGR01673 YP_002739391.1 identified by match to protein family HMM PF01473; match to protein family HMM PF01510 YP_002739393.1 identified by match to protein family HMM PF00383 YP_002739394.1 catalyzes the formation of dUMP from dUTP YP_002739395.1 identified by match to protein family HMM PF00300 YP_002739396.1 Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents YP_002739397.1 identified by match to protein family HMM PF00484 YP_002739399.1 catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP YP_002739404.1 has 3'-5' exonuclease, 5'-3' exonuclease and 5'-3'polymerase activities, primarily functions to fill gaps during DNA replication and repair YP_002739405.1 identified by match to protein family HMM PF02629 YP_002739406.1 identified by match to protein family HMM PF03601 YP_002739407.1 catalyzes the transamination of the aromatic amino acid forming a ketoacid; first step in aromatic amino acid degradation in lactococci YP_002739408.1 involved in DNA repair and RecFOR pathway recombination; RecFOR proteins displace ssDNA-binding protein and facilitate the production of RecA-coated ssDNA YP_002739409.1 involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsY YP_002739412.1 identified by match to protein family HMM TIGR01847 YP_002739414.1 identified by glimmer; putative YP_002739415.1 identified by match to protein family HMM PF01381 YP_002739418.1 identified by glimmer; putative YP_002739419.1 identified by glimmer; putative YP_002739420.1 identified by glimmer; putative YP_002739421.1 identified by match to protein family HMM PF00005; match to protein family HMM PF00664; match to protein family HMM PF03412; match to protein family HMM TIGR01193 YP_002739422.1 identified by match to protein family HMM TIGR01000 YP_002739423.1 catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis; SAICAR synthase YP_002739424.1 identified by match to protein family HMM PF02769; match to protein family HMM TIGR01857 YP_002739425.1 Catalyzes first step of the de novo purine nucleotide biosynthetic pathway YP_002739426.1 catalyzes the formation of 1-(5-phosphoribosyl)-5-aminoimidazole from 2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in purine biosynthesis YP_002739427.1 glycinamide ribonucleotide transformylase; GAR Tfase; catalyzes the synthesis of 5'-phosphoribosylformylglycinamide from 5'-phosphoribosylglycinamide and 10-formyltetrahydrofolate; PurN requires formyl folate for the reaction unlike PurT which uses formate YP_002739428.1 identified by match to protein family HMM PF04892 YP_002739429.1 involved in de novo purine biosynthesis YP_002739430.1 catalyzes the formation of N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-D-ribosylamine and glycine in purine biosynthesis YP_002739432.1 identified by match to protein family HMM PF00731; match to protein family HMM TIGR01162 YP_002739433.1 With PurE catalyzes the conversion of aminoimidazole ribonucleotide to carboxyaminoimidazole ribonucleotide in the de novo purine nucleotide biosynthetic pathway YP_002739435.1 Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide YP_002739436.1 identified by match to protein family HMM PF00728; match to protein family HMM PF00746; match to protein family HMM PF04650; match to protein family HMM PF07501; match to protein family HMM TIGR01167; match to protein family HMM TIGR01168 YP_002739437.1 identified by match to protein family HMM PF00392; match to protein family HMM PF07702 YP_002739438.1 identified by match to protein family HMM PF01301; match to protein family HMM PF02449 YP_002739439.1 identified by match to protein family HMM PF03830 YP_002739440.1 identified by match to protein family HMM PF03609 YP_002739441.1 identified by match to protein family HMM PF03613 YP_002739442.1 identified by match to protein family HMM PF03610 YP_002739443.1 identified by match to protein family HMM PF01380 YP_002739444.1 identified by match to protein family HMM PF01263 YP_002739445.1 identified by match to protein family HMM PF00903 YP_002739446.1 identified by glimmer; putative YP_002739448.1 identified by glimmer; putative YP_002739450.1 identified by match to protein family HMM PF01048 YP_002739452.1 identified by match to protein family HMM PF02386 YP_002739453.1 identified by match to protein family HMM PF02254 YP_002739454.1 identified by glimmer; putative YP_002739455.1 identified by match to protein family HMM PF00535 YP_002739457.1 identified by match to protein family HMM PF00746; match to protein family HMM PF04650; match to protein family HMM TIGR01167; match to protein family HMM TIGR01168 YP_002739458.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00486 YP_002739459.1 identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518 YP_002739460.1 primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination YP_002739461.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002739463.1 identified by match to protein family HMM PF00528 YP_002739464.1 identified by match to protein family HMM PF00528 YP_002739465.1 identified by match to protein family HMM PF01547 YP_002739466.1 identified by match to protein family HMM PF00581 YP_002739471.1 identified by match to protein family HMM PF03551 YP_002739472.1 identified by match to protein family HMM PF07690 YP_002739476.1 identified by match to protein family HMM PF00535 YP_002739477.1 identified by match to protein family HMM PF00106; match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF02719; match to protein family HMM PF04321; match to protein family HMM PF07993 YP_002739479.1 identified by match to protein family HMM PF00702 YP_002739480.1 identified by match to protein family HMM PF03313; match to protein family HMM TIGR00718 YP_002739481.1 identified by match to protein family HMM PF01842; match to protein family HMM PF03315; match to protein family HMM TIGR00719 YP_002739482.1 identified by match to protein family HMM PF01476 YP_002739484.1 identified by match to protein family HMM TIGR01653 YP_002739485.1 identified by match to protein family HMM TIGR01654 YP_002739486.1 identified by match to protein family HMM PF00005 YP_002739487.1 identified by match to protein family HMM PF00497 YP_002739488.1 catalyzes the formation of arginine from (N-L-arginino)succinate YP_002739489.1 identified by match to protein family HMM PF01381 YP_002739490.1 identified by match to protein family HMM PF00005; match to protein family HMM PF00664; match to protein family HMM PF03412; match to protein family HMM TIGR01193 YP_002739498.1 identified by glimmer; putative YP_002739506.1 identified by glimmer; putative YP_002739507.1 identified by match to protein family HMM PF01473 YP_002739508.1 catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs YP_002739509.1 identified by match to protein family HMM PF00293 YP_002739510.1 GidA; glucose-inhibited cell division protein A; involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U) of the wobble uridine base in some tRNAs YP_002739511.1 identified by match to protein family HMM PF00753; match to protein family HMM PF07521; match to protein family HMM TIGR00649 YP_002739512.1 identified by match to protein family HMM PF07288 YP_002739513.1 identified by match to protein family HMM TIGR01847 YP_002739515.1 identified by match to protein family HMM PF00814 YP_002739516.1 identified by match to protein family HMM PF00583; match to protein family HMM TIGR01575 YP_002739517.1 in most organisms, only the N-terminal domain is present in a single polypeptide; in some archaea this domain is fused to a kinase domain; this gene is essential for growth in Escherichia coli and Bacillus subtilis; the secreted glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins; the Pyrococcus structure shows DNA-binding properties, iron-binding, ATP-binding, and AP endonuclease activity YP_002739518.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002739519.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by match to protein family HMM PF01610 YP_002739521.1 identified by match to protein family HMM PF00005 YP_002739523.1 identified by match to protein family HMM PF02585 YP_002739524.1 identified by match to protein family HMM TIGR01716 YP_002739525.1 identified by glimmer; putative YP_002739526.1 identified by match to protein family HMM PF02517 YP_002739529.1 identified by match to protein family HMM PF05437 YP_002739530.1 identified by match to protein family HMM PF00497 YP_002739531.1 identified by match to protein family HMM PF03180 YP_002739532.1 identified by match to protein family HMM PF01546; match to protein family HMM PF07687 YP_002739533.1 identified by match to protein family HMM PF00005 YP_002739534.1 identified by match to protein family HMM PF00528 YP_002739535.1 identified by match to protein family HMM TIGR02185 YP_002739536.1 identified by match to protein family HMM PF04854 YP_002739537.1 identified by match to protein family HMM PF00672; match to protein family HMM PF02518; match to protein family HMM PF06580 YP_002739538.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00165 YP_002739540.1 has a stimulatory effect on the ribonucleotide reductase activity of NrdH with NrdEF YP_002739543.1 identified by match to protein family HMM PF04397 YP_002739546.1 RibE; 6,7-diimethyl-8-ribityllumazine synthase; DMRL synthase; lumazine synthase; beta subunit of riboflavin synthase; condenses 5-amino-6-(1'-D)-ribityl-amino-2,4(1H,3H)-pyrimidinedione with L-3,4-dihydrohy-2-butanone-4-phosphate to generate 6,6-dimethyl-8-lumazine (DMRL); riboflavin synthase then uses 2 molecules of DMRL to produce riboflavin (vitamin B12); involved in the last steps of riboflavin biosynthesis; forms a 60mer (icosahedral shell) in both Bacillus subtilis and Escherichia coli; in Bacillus subtilis this 60mer is associated with the riboflavin synthase subunit (alpha) while in Escherichia coli it is not YP_002739547.1 identified by match to protein family HMM PF00925; match to protein family HMM PF00926; match to protein family HMM TIGR00505; match to protein family HMM TIGR00506 YP_002739548.1 catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine YP_002739549.1 identified by match to protein family HMM PF00383; match to protein family HMM PF01872; match to protein family HMM TIGR00227; match to protein family HMM TIGR00326 YP_002739550.1 plays an essential role in ATP-dependent branch migration of the Holliday junction YP_002739551.1 identified by match to protein family HMM PF03352 YP_002739552.1 identified by match to protein family HMM PF02517 YP_002739553.1 identified by match to protein family HMM PF02016 YP_002739554.1 identified by match to protein family HMM PF06570 YP_002739555.1 identified by match to protein family HMM PF01544 YP_002739556.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate YP_002739557.1 identified by match to protein family HMM PF00557; match to protein family HMM PF01321 YP_002739558.1 the anti-alpha factor Spx interacts with RNA polymerase alpha subunit C-terminal domain in a region that interacts with the sigma 70 subunit and may interfere with activation of promoters; in Bacillus subtilis this protein is a substrate for ClpXP protease; blocks transcription of the competence regulatory gene encoded by the srf operon; regulates a number of genes involved in thiol homeostasis including trxA and trxB; monomeric member of ArsC family of proteins; does not bind DNA; contains a disulfide bond between C10 and C13 which may sense disulfide stress YP_002739560.1 identified by match to protein family HMM PF06135 YP_002739561.1 similar to RuvC resolvase with substantial differences; NMR structural information suggests this protein is monomeric; unknown cellular function YP_002739562.1 identified by match to protein family HMM PF06949 YP_002739563.1 identified by match to protein family HMM PF02875; match to protein family HMM PF08245; match to protein family HMM TIGR01499 YP_002739565.1 identified by match to protein family HMM PF00614 YP_002739567.1 Catalyzes the reduction of nucleoside 5'-triphosphates to 2'-deoxynucleoside 5'-triphosphates YP_002739569.1 identified by match to protein family HMM PF00583 YP_002739570.1 identified by match to protein family HMM PF04055; match to protein family HMM TIGR02491 YP_002739571.1 identified by match to protein family HMM PF00485 YP_002739572.1 NusE; involved in assembly of the 30S subunit; in the ribosome, this protein is involved in the binding of tRNA; in Escherichia coli this protein was also found to be involved in transcription antitermination; NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination; binding of NusB/S10 to boxA nucleates assembly of the antitermination complex YP_002739573.1 binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin YP_002739574.1 L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA YP_002739575.1 binds third domain of 23S rRNA and protein L29; part of exit tunnel YP_002739576.1 one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation YP_002739577.1 protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA YP_002739578.1 binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center YP_002739579.1 forms a complex with S10 and S14; binds the lower part of the 30S subunit head and the mRNA in the complete ribosome to position it for translation YP_002739580.1 located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e YP_002739581.1 one of the stabilizing components for the large ribosomal subunit YP_002739582.1 primary binding protein; helps mediate assembly; involved in translation fidelity YP_002739583.1 binds to the 23S rRNA between the centers for peptidyl transferase and GTPase YP_002739584.1 assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel YP_002739585.1 part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13 YP_002739586.1 located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group do not appear to have the zinc-binding motif YP_002739587.1 binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit YP_002739588.1 ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance YP_002739589.1 binds 5S rRNA along with protein L5 and L25 YP_002739590.1 located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance YP_002739591.1 L30 binds domain II of the 23S rRNA and the 5S rRNA; similar to eukaryotic protein L7 YP_002739592.1 late assembly protein YP_002739593.1 forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase YP_002739594.1 essential enzyme that recycles AMP in active cells; converts ATP and AMP to two molecules of ADP YP_002739595.1 stimulates the activities of the other two initiation factors, IF-2 and IF-3 YP_002739596.1 smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group have the motif YP_002739597.1 located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA YP_002739598.1 located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3 YP_002739599.1 catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme YP_002739600.1 is a component of the macrolide binding site in the peptidyl transferase center YP_002739601.1 ACT domain-containing protein YP_002739602.1 identified by match to protein family HMM PF05167 YP_002739603.1 identified by match to protein family HMM PF00300 YP_002739607.1 identified by match to protein family HMM PF04055; match to protein family HMM TIGR02494 YP_002739608.1 identified by match to protein family HMM PF00455; match to protein family HMM PF08220; match to protein family HMM PF08279 YP_002739609.1 identified by match to protein family HMM PF04198 YP_002739610.1 identified by match to protein family HMM PF02255 YP_002739611.1 identified by match to protein family HMM PF02302 YP_002739612.1 identified by match to protein family HMM PF02378; match to protein family HMM TIGR00410 YP_002739613.1 identified by match to protein family HMM PF01228; match to protein family HMM PF02901; match to protein family HMM TIGR01774 YP_002739614.1 similar to transaldolase from Escherichia coli; many organisms have multiple copies YP_002739615.1 forms dimers and octamers; involved in conversion of glycerol to dihydroxy-acetone YP_002739616.1 leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase YP_002739617.1 identified by match to protein family HMM PF00583 YP_002739618.1 identified by match to protein family HMM PF00583 YP_002739619.1 promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration YP_002739620.1 identified by match to protein family HMM PF06042 YP_002739621.1 catalyzes the formation of undecaprenyl pyrophosphate from isopentenyl pyrophosphate YP_002739622.1 identified by match to protein family HMM PF01148 YP_002739623.1 identified by match to protein family HMM PF02163; match to protein family HMM TIGR00054 YP_002739624.1 catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro) YP_002739625.1 identified by match to protein family HMM PF00232 YP_002739626.1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source YP_002739627.1 identified by match to protein family HMM PF00296 YP_002739628.1 identified by match to protein family HMM PF00128; match to protein family HMM PF00746; match to protein family HMM PF02922; match to protein family HMM PF03714; match to protein family HMM PF04650; match to protein family HMM TIGR01167; match to protein family HMM TIGR01168; match to protein family HMM TIGR02102 YP_002739629.1 interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance YP_002739630.1 binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit YP_002739631.1 EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene YP_002739632.1 catalyzes DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time; required for leading strand synthesis; PolC exhibits 3' to 5' exonuclease activity YP_002739633.1 identified by match to protein family HMM PF04221; match to protein family HMM TIGR02384 YP_002739634.1 identified by match to protein family HMM PF05016; match to protein family HMM TIGR02385 YP_002739636.1 identified by match to protein family HMM PF02073 YP_002739637.1 identified by match to protein family HMM PF04226 YP_002739639.1 identified by match to protein family HMM PF00849; match to protein family HMM PF01479; match to protein family HMM TIGR00093 YP_002739640.1 identified by match to protein family HMM PF03051 YP_002739641.1 identified by match to protein family HMM PF03613; match to protein family HMM TIGR00828 YP_002739642.1 identified by match to protein family HMM PF03609 YP_002739643.1 identified by match to protein family HMM PF03610; match to protein family HMM PF03830 YP_002739644.1 similar to zinc-dependent eukaryotic ADH enzymes and distinct from fermentative ADHs YP_002739645.1 identified by match to protein family HMM PF00702; match to protein family HMM PF05116; match to protein family HMM PF08282; match to protein family HMM TIGR00099; match to protein family HMM TIGR01484 YP_002739646.1 identified by match to protein family HMM PF00860 YP_002739647.1 identified by match to protein family HMM PF02517 YP_002739648.1 identified by match to protein family HMM PF00809; match to protein family HMM TIGR01496 YP_002739649.1 identified by match to protein family HMM PF02875; match to protein family HMM PF08245; match to protein family HMM TIGR01499 YP_002739650.1 involved in the first step of tetrahydrofolate biosynthesis; catalyzes the formation of formate and 2-amino-4-hydroxy-6-(erythro-1,2, 3-trihydroxypropyl)dihydropteridine triphosphate from GTP and water; forms a homopolymer YP_002739651.1 identified by match to protein family HMM PF01288; match to protein family HMM PF02152; match to protein family HMM TIGR00525; match to protein family HMM TIGR00526; match to protein family HMM TIGR01498 YP_002739653.1 in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit YP_002739654.1 forms a direct contact with the tRNA during translation YP_002739655.1 identified by match to protein family HMM PF00589 YP_002739656.1 identified by glimmer; putative YP_002739658.1 identified by glimmer; putative YP_002739659.1 identified by glimmer; putative YP_002739660.1 identified by glimmer; putative YP_002739664.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by match to protein family HMM PF01710 YP_002739665.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002739667.1 converts 6-phospho-beta-D-glucosyl-(1,4)-D-glucose to glucose and glucose 6-phosphate; required for cellobiose uptake and metabolism YP_002739668.1 identified by match to protein family HMM PF03083 YP_002739669.1 required for cellobiose uptake and metabolism YP_002739670.1 identified by match to protein family HMM PF00874; match to protein family HMM PF05043; match to protein family HMM PF08279 YP_002739671.1 required for cellobiose uptake and metabolism YP_002739673.1 required for cellobiose uptake and metabolism YP_002739675.1 identified by match to protein family HMM PF01055 YP_002739676.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by match to protein family HMM PF01609 YP_002739677.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002739678.1 identified by match to protein family HMM PF00255 YP_002739679.1 identified by match to protein family HMM PF00746; match to protein family HMM PF02018; match to protein family HMM PF02278; match to protein family HMM PF02884; match to protein family HMM PF08124; match to protein family HMM TIGR01167 YP_002739680.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002739681.1 catalyzes the formation of pyruvate and glyoxylate from 4-hydroxy-2-oxoglutarate; or pyruvate and D-glyceraldehyde 3-phosphate from 2-dehydro-3-deoxy-D-glyconate 6-phosphate YP_002739682.1 identified by match to protein family HMM PF00294 YP_002739683.1 identified by match to protein family HMM PF02502 YP_002739684.1 Involved in the nonphosphorylative, ketogenic oxidation of glucose and oxidizes gluconate to 5-ketogluconate YP_002739685.1 identified by match to protein family HMM PF03610 YP_002739686.1 identified by match to protein family HMM PF07470 YP_002739687.1 identified by match to protein family HMM PF03830 YP_002739688.1 identified by match to protein family HMM PF03609 YP_002739689.1 identified by match to protein family HMM PF03613 YP_002739691.1 identified by match to protein family HMM PF07940 YP_002739692.1 identified by match to protein family HMM PF00356; match to protein family HMM PF00532 YP_002739693.1 identified by glimmer; putative YP_002739696.1 identified by match to protein family HMM PF01381 YP_002739697.1 identified by match to protein family HMM PF01795; match to protein family HMM TIGR00006 YP_002739698.1 identified by match to protein family HMM TIGR02209 YP_002739699.1 identified by match to protein family HMM PF00905; match to protein family HMM PF03717; match to protein family HMM PF03793 YP_002739700.1 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan YP_002739702.1 identified by match to protein family HMM PF00004; match to protein family HMM PF07724; match to protein family HMM PF07728 YP_002739704.1 catalyzes the hydrolysis of S-ribosylhomocysteine to homocysteine and autoinducer-2 YP_002739705.1 identified by match to protein family HMM PF08903 YP_002739706.1 identified by match to protein family HMM PF00128 YP_002739708.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002739709.1 identified by glimmer; putative YP_002739710.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by match to protein family HMM PF01710 YP_002739711.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002739712.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by match to protein family HMM PF01609 YP_002739713.1 identified by match to protein family HMM PF02916; match to protein family HMM PF03816; match to protein family HMM TIGR00350 YP_002739714.1 identified by match to protein family HMM PF02811 YP_002739715.1 identified by match to protein family HMM PF02706; match to protein family HMM TIGR01006 YP_002739716.1 identified by match to protein family HMM TIGR01007 YP_002739717.1 identified by match to protein family HMM PF02397 YP_002739718.1 identified by match to protein family HMM PF00534 YP_002739720.1 identified by match to protein family HMM PF01943; match to protein family HMM PF03023 YP_002739721.1 identified by match to protein family HMM PF00535 YP_002739722.1 identified by match to protein family HMM PF00534 YP_002739724.1 identified by match to protein family HMM PF00106; match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF02719; match to protein family HMM PF04321; match to protein family HMM PF07993; match to protein family HMM PF08485 YP_002739725.1 identified by match to protein family HMM PF00984; match to protein family HMM PF01210; match to protein family HMM PF03720; match to protein family HMM PF03721; match to protein family HMM TIGR03026 YP_002739726.1 identified by match to protein family HMM PF01370; match to protein family HMM PF07993 YP_002739727.1 identified by match to protein family HMM PF02350; match to protein family HMM TIGR00236 YP_002739729.1 identified by match to protein family HMM PF05717 YP_002739730.1 identified by glimmer; putative YP_002739732.1 identified by match to protein family HMM PF00496 YP_002739733.1 identified by match to protein family HMM PF00754; match to protein family HMM PF04650; match to protein family HMM TIGR01167; match to protein family HMM TIGR01168 YP_002739734.1 identified by match to protein family HMM PF00905; match to protein family HMM PF00912; match to protein family HMM TIGR02074 YP_002739735.1 functions in homologous recombination, DNA repair, and chromosome segregation; binds preferentially to three- and four-stranded DNA intermediates; introduces specific nick sites in four-stranded DNA substrates; functions similarly to Escherichia coli RuvC YP_002739736.1 identified by match to protein family HMM PF06908 YP_002739737.1 identified by match to protein family HMM PF05103 YP_002739738.1 identified by match to protein family HMM PF01170 YP_002739740.1 catalyzes the formation of D-ribulose 5-phosphate from 6-phospho-D-gluconate YP_002739741.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00486 YP_002739742.1 identified by match to protein family HMM PF01473 YP_002739744.1 identified by glimmer; putative YP_002739745.1 identified by match to protein family HMM PF01473 YP_002739746.1 identified by match to protein family HMM PF00288; match to protein family HMM PF08544; match to protein family HMM TIGR00549 YP_002739747.1 identified by match to protein family HMM PF00288; match to protein family HMM PF08544; match to protein family HMM TIGR01240 YP_002739748.1 identified by match to protein family HMM PF00288; match to protein family HMM PF08544; match to protein family HMM TIGR01220 YP_002739749.1 catalyzes the isomerization of isopentenyl pyrophosphate to dimethylallyl diphosphate YP_002739751.1 identified by match to protein family HMM PF02518; match to protein family HMM PF07730 YP_002739752.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00196; match to protein family HMM PF08281 YP_002739753.1 identified by glimmer; putative YP_002739756.1 identified by match to protein family HMM PF01473 YP_002739757.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by match to protein family HMM PF00665 YP_002739758.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002739759.1 identified by match to protein family HMM PF02302; match to protein family HMM PF02378; match to protein family HMM TIGR00851 YP_002739760.1 identified by match to protein family HMM PF08279 YP_002739761.1 identified by match to protein family HMM PF00359 YP_002739762.1 identified by match to protein family HMM PF01232; match to protein family HMM PF08125 YP_002739764.1 Tig; RopA; peptidyl-prolyl cis/trans isomerase; promotes folding of newly synthesized proteins; binds ribosomal 50S subunit; forms a homodimer YP_002739765.1 identified by match to protein family HMM TIGR01448 YP_002739766.1 identified by match to protein family HMM PF00717; match to protein family HMM TIGR02227 YP_002739767.1 An endonuclease that specifically degrades the RNA strand of RNA-DNA hybrids YP_002739769.1 identified by match to protein family HMM PF02674 YP_002739770.1 identified by match to protein family HMM PF00488; match to protein family HMM PF01713; match to protein family HMM TIGR01069 YP_002739771.1 identified by match to protein family HMM PF01235; match to protein family HMM TIGR00835 YP_002739772.1 identified by match to protein family HMM PF02627; match to protein family HMM TIGR00778 YP_002739773.1 identified by match to protein family HMM PF03595 YP_002739774.1 catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_002739775.1 identified by match to protein family HMM PF06115 YP_002739776.1 catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP; lysine and threonine sensitive YP_002739778.1 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA YP_002739779.1 identified by match to protein family HMM PF01047; match to protein family HMM PF03965 YP_002739780.1 FabH; beta-ketoacyl-acyl carrier protein synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs YP_002739781.1 carries the fatty acid chain in fatty acid biosynthesis YP_002739782.1 identified by match to protein family HMM PF03060; match to protein family HMM TIGR03151 YP_002739783.1 identified by match to protein family HMM PF00698; match to protein family HMM TIGR00128 YP_002739784.1 catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis YP_002739785.1 FabF; beta-ketoacyl-ACP synthase II, KASII; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP YP_002739786.1 composes the biotin carboxyl carrier protein subunit of the acetyl-CoA carboxylase complex, the enzyme that catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, which in turn controls the rate of fatty acid metabolism YP_002739787.1 in Pseudomonas aeruginosa this enzyme is a trimer of dimers; essential for membrane formation; performs third step of type II fatty acid biosynthesis; catalyzes dehydration of (3R)-hydroxyacyl-ACP to trans-2-acyl-ACP YP_002739788.1 an AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism YP_002739789.1 catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer of AccA2D2 subunits YP_002739790.1 catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer composed of two alpha (AccA) and two beta (AccD) subunits; one of the two catalytic subunits that can form the acetyl CoA carboxylase enzyme together with a carrier protein; these proteins present a shorter N-terminus YP_002739793.1 identified by match to protein family HMM PF02517 YP_002739794.1 Regulates rRNA biosynthesis by transcriptional antitermination YP_002739795.1 identified by match to protein family HMM PF03780 YP_002739796.1 Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA YP_002739797.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA YP_002739798.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA YP_002739799.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; some Mycoplasma proteins contain an N-terminal fusion to an unknown domain YP_002739800.1 stimulates the release of release factors 1 and 2 from the ribosome after hydrolysis of the ester bond in peptidyl-tRNA has occurred; GDP/GTP-binding protein YP_002739801.1 required for 70S ribosome assembly YP_002739802.1 identified by match to protein family HMM PF03780 YP_002739803.1 identified by match to protein family HMM PF02734 YP_002739804.1 catalyzes the formation of 2-acetolactate from pyruvate; also known as acetolactate synthase large subunit YP_002739805.1 with IlvI catalyzes the formation of 2-acetolactate from pyruvate, the small subunit is required for full activity and valine sensitivity; E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates, valine sensitivity and affinity for cofactors; also known as acetolactate synthase 3 small subunit YP_002739806.1 catalyzes the formation of (R)-2,3-dihydroxy-3-methylbutanoate from (S)-2-hydroxy-2-methyl-3-oxobutanoate in valine and isoleucine biosynthesis YP_002739809.1 catalyzes the formation of 2-oxobutanoate from L-threonine; biosynthetic YP_002739812.1 identified by match to protein family HMM PF00005 YP_002739813.1 identified by match to protein family HMM PF00497; match to protein family HMM PF00528; match to protein family HMM TIGR01726 YP_002739816.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by match to protein family HMM PF02371 YP_002739817.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002739818.1 BacA; phosphatase activity in Escherichia coli not kinase; involved in bacitracin resistance as bacitracin supposedly sequesters undecaprenyl disphosphate which reduces the pool of lipid carrier available to the cell YP_002739820.1 involved in translesion DNA polymerization with beta clamp of polymerase III; belongs to Y family of polymerases; does not contain proofreading function YP_002739821.1 identified by glimmer; putative YP_002739822.1 identified by match to protein family HMM PF01228; match to protein family HMM PF02901; match to protein family HMM TIGR01255 YP_002739826.1 identified by match to protein family HMM PF00480 YP_002739827.1 identified by match to protein family HMM PF02378; match to protein family HMM TIGR00410 YP_002739829.1 identified by match to protein family HMM PF02255 YP_002739830.1 catalyzes the formation of 6-phospho-galactose from a 6-phospho-beta-galactoside YP_002739831.1 identified by match to protein family HMM PF02302; match to protein family HMM PF02378 YP_002739832.1 identified by match to protein family HMM PF02386 YP_002739833.1 involved in potassium uptake; found to be peripherally associated with the inner membrane in Escherichia coli; contains an NAD-binding domain YP_002739834.1 identified by match to protein family HMM PF01887 YP_002739835.1 identified by match to protein family HMM PF07155 YP_002739837.1 identified by match to protein family HMM PF00005 YP_002739838.1 identified by match to protein family HMM PF02361 YP_002739839.1 identified by match to protein family HMM PF00588 YP_002739841.1 identified by match to protein family HMM PF01569 YP_002739844.1 participates in both the initiation and recycling phases of transcription; in the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling YP_002739845.1 identified by glimmer; putative YP_002739846.1 CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer YP_002739847.1 identified by match to protein family HMM PF01895; match to protein family HMM PF02690; match to protein family HMM TIGR00704 YP_002739848.1 identified by match to protein family HMM PF00746; match to protein family HMM PF00754; match to protein family HMM PF03644; match to protein family HMM PF07501; match to protein family HMM PF07523; match to protein family HMM TIGR01167 YP_002739849.1 Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway YP_002739851.1 identified by match to protein family HMM PF00376 YP_002739852.1 identified by match to protein family HMM PF00120; match to protein family HMM PF03951; match to protein family HMM TIGR00653 YP_002739854.1 identified by glimmer; putative YP_002739856.1 identified by match to protein family HMM PF01420 YP_002739857.1 identified by match to protein family HMM PF02384 YP_002739858.1 identified by match to protein family HMM PF00270; match to protein family HMM PF04313; match to protein family HMM PF04851; match to protein family HMM PF08463 YP_002739861.1 Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons YP_002739862.1 with DnaK and DnaJ acts in response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins; may act as a thermosensor YP_002739863.1 heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria YP_002739865.1 chaperone Hsp40; co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion YP_002739868.1 identified by match to protein family HMM PF01230 YP_002739869.1 identified by match to protein family HMM PF00005 YP_002739870.1 identified by match to protein family HMM PF05975 YP_002739872.1 identified by match to protein family HMM PF04397 YP_002739873.1 identified by match to protein family HMM PF00072; match to protein family HMM PF04397 YP_002739874.1 identified by match to protein family HMM PF02518 YP_002739875.1 identified by match to protein family HMM PF08128; match to protein family HMM TIGR01847 YP_002739876.1 identified by match to protein family HMM TIGR01000 YP_002739878.1 identified by match to protein family HMM TIGR01847 YP_002739879.1 identified by match to protein family HMM TIGR01847 YP_002739880.1 identified by glimmer; putative YP_002739884.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002739885.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by match to protein family HMM PF01609 YP_002739886.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002739887.1 identified by match to protein family HMM PF01609 YP_002739888.1 identified by match to protein family HMM TIGR01847 YP_002739890.1 identified by match to protein family HMM TIGR01847 YP_002739895.1 identified by match to protein family HMM PF02517 YP_002739897.1 identified by match to protein family HMM PF02517 YP_002739898.1 identified by match to protein family HMM PF01636 YP_002739899.1 tRNA (guanine-N(7)-)-methyltransferase; catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA by transferring the methyl residue from S-adenosyl-L-methionine YP_002739900.1 in Streptococcus pneumoniae this gene was found to be essential; structure determination of the Streptococcus protein shows that it is similar to a number of other proteins YP_002739901.1 modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination YP_002739902.1 identified by match to protein family HMM PF04296 YP_002739903.1 identified by match to protein family HMM PF01248 YP_002739904.1 Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex YP_002739905.1 associates with free 30S ribosomal subunits; essential for efficient processing of 16S rRNA; in Escherichia coli rbfA is induced by cold shock YP_002739906.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002739907.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002739910.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002739911.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by match to protein family HMM PF01609 YP_002739912.1 identified by match to protein family HMM PF08984 YP_002739913.1 identified by match to protein family HMM PF01814; match to protein family HMM PF04282 YP_002739914.1 identified by match to protein family HMM PF08930 YP_002739917.1 identified by match to protein family HMM PF00583 YP_002739919.1 valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain YP_002739921.1 identified by match to protein family HMM PF02661 YP_002739922.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002739923.1 identified by match to protein family HMM PF00874; match to protein family HMM PF03123 YP_002739924.1 identified by match to protein family HMM PF00358; match to protein family HMM PF00367; match to protein family HMM PF02378; match to protein family HMM TIGR00830; match to protein family HMM TIGR01995 YP_002739925.1 identified by match to protein family HMM PF00232 YP_002739926.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily YP_002739927.1 identified by match to protein family HMM PF00583 YP_002739928.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily YP_002739929.1 identified by match to protein family HMM PF03372 YP_002739930.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002739931.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002739932.1 identified by match to protein family HMM PF01381 YP_002739933.1 catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine to form methionine YP_002739934.1 identified by match to protein family HMM PF02219; match to protein family HMM TIGR00676 YP_002739935.1 identified by match to protein family HMM PF00013; match to protein family HMM PF00575; match to protein family HMM PF01138; match to protein family HMM PF03725; match to protein family HMM PF03726 YP_002739936.1 identified by match to protein family HMM TIGR01172 YP_002739937.1 identified by match to protein family HMM PF00583 YP_002739938.1 catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA YP_002739939.1 identified by match to protein family HMM PF00636 YP_002739944.1 identified by match to protein family HMM PF02687 YP_002739945.1 identified by match to protein family HMM PF00005 YP_002739946.1 identified by match to protein family HMM PF02687 YP_002739947.1 identified by glimmer; putative YP_002739948.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00486 YP_002739949.1 identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518 YP_002739950.1 catalyzes the formation of glycerone phosphate and glyceraldehyde 3-phosphate from fructose 1,6, bisphosphate YP_002739951.1 identified by match to protein family HMM PF00175; match to protein family HMM PF00970; match to protein family HMM PF01794 YP_002739952.1 identified by match to protein family HMM PF00528; match to protein family HMM TIGR01726 YP_002739953.1 identified by match to protein family HMM PF00528; match to protein family HMM TIGR01726 YP_002739954.1 identified by match to protein family HMM PF00497 YP_002739955.1 identified by match to protein family HMM PF00005 YP_002739956.1 identified by match to protein family HMM PF01368; match to protein family HMM PF02272; match to protein family HMM TIGR00644 YP_002739957.1 identified by match to protein family HMM PF00753; match to protein family HMM PF07521 YP_002739958.1 identified by match to protein family HMM PF00756 YP_002739959.1 identified by match to protein family HMM PF02388 YP_002739960.1 identified by match to protein family HMM PF02388 YP_002739961.1 identified by match to protein family HMM PF00413 YP_002739962.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision YP_002739964.1 identified by match to protein family HMM PF00497 YP_002739965.1 identified by match to protein family HMM PF00881 YP_002739966.1 divalent metal ion-dependent extracellular dipeptidase; able to hydrolyze a broad range of dipeptides but no tri-, tetra-, or larger oligopeptides; differences in the amino acid specificity of the cleavage site varies between species; similar to succinyl-diaminopimelate desuccinylases YP_002739967.1 identified by match to protein family HMM PF03167 YP_002739970.1 identified by match to protein family HMM PF05525; match to protein family HMM TIGR00796 YP_002739971.1 identified by match to protein family HMM PF05343 YP_002739972.1 identified by match to protein family HMM PF01230 YP_002739973.1 identified by match to protein family HMM PF02557 YP_002739974.1 binds directly to 23S ribosomal RNA YP_002739975.1 in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA YP_002739978.1 identified by glimmer; putative YP_002739979.1 identified by match to protein family HMM PF00005 YP_002739980.1 identified by match to protein family HMM PF06182 YP_002739981.1 identified by match to protein family HMM PF06182 YP_002739983.1 identified by match to protein family HMM PF00082; match to protein family HMM PF00746; match to protein family HMM PF02225; match to protein family HMM PF05922; match to protein family HMM PF06280; match to protein family HMM TIGR01167 YP_002739984.1 identified by match to protein family HMM PF00359 YP_002739986.1 identified by match to protein family HMM PF03611 YP_002739988.1 identified by match to protein family HMM PF00703; match to protein family HMM PF00746; match to protein family HMM PF02836; match to protein family HMM PF02837; match to protein family HMM PF04650; match to protein family HMM PF07501; match to protein family HMM PF07532; match to protein family HMM TIGR01167; match to protein family HMM TIGR01168 YP_002739989.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002739990.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002739992.1 identified by match to protein family HMM PF06962 YP_002739994.1 identified by match to protein family HMM PF00999 YP_002739995.1 identified by match to protein family HMM PF03631 YP_002739996.1 identified by match to protein family HMM PF02683 YP_002739997.1 identified by match to protein family HMM PF00578; match to protein family HMM PF08534 YP_002739998.1 identified by match to protein family HMM PF01625; match to protein family HMM PF01641; match to protein family HMM TIGR00357; match to protein family HMM TIGR00401 YP_002739999.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00165 YP_002740000.1 identified by match to protein family HMM PF00672; match to protein family HMM PF02518; match to protein family HMM PF02743; match to protein family HMM PF06580 YP_002740001.1 identified by match to protein family HMM PF04260; match to protein family HMM TIGR01440 YP_002740002.1 identified by match to protein family HMM PF00746; match to protein family HMM PF05342; match to protein family HMM PF07501; match to protein family HMM PF07580; match to protein family HMM TIGR01167 YP_002740003.1 identified by match to protein family HMM PF00425; match to protein family HMM TIGR00553 YP_002740005.1 identified by match to protein family HMM PF01473; match to protein family HMM PF05901; match to protein family HMM PF07553 YP_002740006.1 identified by match to protein family HMM PF00480; match to protein family HMM TIGR00744 YP_002740007.1 ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived YP_002740009.1 IPP transferase; isopentenyltransferase; involved in tRNA modification; in Escherichia coli this enzyme catalyzes the addition of a delta2-isopentenyl group from dimethylallyl diphosphate to the N6-nitrogen of adenosine adjacent to the anticodon of tRNA species that read codons starting with uracil; further tRNA modifications may occur; mutations in miaA result in defects in translation efficiency and fidelity YP_002740010.1 identified by match to protein family HMM PF01926; match to protein family HMM TIGR00231; match to protein family HMM TIGR03156 YP_002740012.1 member of metallo-beta-lactamase family; the purified enzyme from Escherichia coli forms dimeric zinc phosphodiesterase; in Bacillus subtilis this protein is a 3'-tRNA processing endoribonuclease and is essential while in Escherichia coli it is not; associates with two zinc ions YP_002740013.1 identified by match to protein family HMM PF00106; match to protein family HMM PF08659 YP_002740014.1 identified by match to protein family HMM PF00126 YP_002740015.1 identified by match to protein family HMM PF06014 YP_002740016.1 identified by match to protein family HMM PF00581 YP_002740018.1 identified by match to protein family HMM PF00849; match to protein family HMM PF01479; match to protein family HMM TIGR00093 YP_002740019.1 identified by match to protein family HMM PF00009; match to protein family HMM PF00679; match to protein family HMM PF03144; match to protein family HMM TIGR00231; match to protein family HMM TIGR01394 YP_002740021.1 identified by match to protein family HMM TIGR01653 YP_002740022.1 identified by match to protein family HMM PF07242; match to protein family HMM TIGR01654 YP_002740023.1 identified by match to protein family HMM PF00005 YP_002740024.1 UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation YP_002740025.1 UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; involved in cell wall formation; inner membrane-associated; last step of peptidoglycan synthesis YP_002740026.1 identified by match to protein family HMM PF03799; match to protein family HMM PF08478 YP_002740027.1 type 1 subfamily; involved in last step of pyrimidine biosynthesis; converts orotidine 5'-phosphate to UMP and carbon dioxide; OMP decarboxylase; OMPDCase; OMPdecase YP_002740028.1 involved in fifth step of pyrimidine biosynthesis; converts orotidine 5'-phosphate and diphosphate to orotate and 5-phospho-alpha-D-ribose 1-diphosphate YP_002740029.1 identified by glimmer; putative YP_002740033.1 identified by match to protein family HMM PF00005 YP_002740034.1 identified by match to protein family HMM PF00497 YP_002740035.1 identified by match to protein family HMM PF00528; match to protein family HMM TIGR01726 YP_002740036.1 identified by match to protein family HMM PF00528; match to protein family HMM TIGR01726 YP_002740038.1 class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1 YP_002740039.1 identified by match to protein family HMM PF01070; match to protein family HMM TIGR02708 YP_002740040.1 identified by match to protein family HMM PF03070 YP_002740042.1 catalyzes the formation of 4-methyl-5-(2-phosphoethyl)-thiazole and ADP from 4-methyl-5-(2-hydroxyethyl)-thiazole and ATP YP_002740043.1 identified by match to protein family HMM PF02581; match to protein family HMM TIGR00693 YP_002740045.1 identified by match to protein family HMM PF00005 YP_002740047.1 identified by match to protein family HMM PF03070 YP_002740048.1 identified by match to protein family HMM TIGR02359 YP_002740049.1 identified by match to protein family HMM PF02110 YP_002740050.1 Condenses 4-methyl-5-(beta-hydroxyethyl)-thiazole monophosphate and 4-amino-5-hydroxymethyl pyrimidine pyrophosphate to form thiamine monophosphate YP_002740051.1 catalyzes the formation of 4-amino-2-methyl-5-diphosphomethylpyrimidine YP_002740052.1 identified by match to protein family HMM PF03965; match to protein family HMM TIGR02698 YP_002740054.1 identified by match to protein family HMM PF00122; match to protein family HMM PF00702; match to protein family HMM PF08282; match to protein family HMM TIGR01494; match to protein family HMM TIGR01511; match to protein family HMM TIGR01525 YP_002740055.1 identified by match to protein family HMM PF00205; match to protein family HMM PF02775; match to protein family HMM PF02776; match to protein family HMM TIGR02720 YP_002740056.1 identified by match to protein family HMM PF00903 YP_002740060.1 identified by match to protein family HMM PF01238; match to protein family HMM TIGR00218 YP_002740061.1 identified by match to protein family HMM PF00293 YP_002740062.1 identified by match to protein family HMM PF03486; match to protein family HMM TIGR00275 YP_002740063.1 identified by match to protein family HMM PF02645 YP_002740064.1 identified by match to protein family HMM PF00440 YP_002740065.1 identified by match to protein family HMM PF00383 YP_002740066.1 Catalyzes the formation of uracil and 5-phospho-alpha-D-ribosy 1-diphosphate from UMP and diphosphate YP_002740067.1 hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates YP_002740069.1 identified by match to protein family HMM PF01094 YP_002740070.1 identified by match to protein family HMM PF02653 YP_002740071.1 identified by match to protein family HMM PF02653 YP_002740072.1 identified by match to protein family HMM PF00005 YP_002740073.1 identified by match to protein family HMM PF00005 YP_002740074.1 identified by match to protein family HMM PF00571 YP_002740075.1 recognizes the termination signals UGA and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF2; in some organisms control of PrfB protein levels is maintained through a +1 ribosomal frameshifting mechanism; this protein is similar to release factor 1 YP_002740076.1 identified by match to protein family HMM PF00005; match to protein family HMM TIGR02673 YP_002740077.1 identified by match to protein family HMM PF02687 YP_002740078.1 identified by match to protein family HMM PF00358; match to protein family HMM PF00367; match to protein family HMM PF02378; match to protein family HMM TIGR00826; match to protein family HMM TIGR00830; match to protein family HMM TIGR02003 YP_002740079.1 identified by match to protein family HMM PF03372 YP_002740080.1 identified by match to protein family HMM PF00270; match to protein family HMM PF00271 YP_002740081.1 catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase YP_002740082.1 catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway; subclass 1A is a dimer formed by two identical PyrD subunits each containing an FMN group YP_002740083.1 required for the assembly and function of the DNAX complex which is required for the assembly of the beta subunit onto primed DNA YP_002740084.1 identified by match to protein family HMM PF00081; match to protein family HMM PF02777 YP_002740085.1 identified by match to protein family HMM PF06265 YP_002740086.1 23S rRNA m2A2503 methyltransferase; methylates the C2 position of the A2530 nucleotide in 23S rRNA; may be involved in antibiotic resistance YP_002740087.1 identified by match to protein family HMM PF04892 YP_002740088.1 identified by match to protein family HMM PF00005 YP_002740089.1 identified by match to protein family HMM PF00160 YP_002740092.1 binds to lower part of 30S body where it stabilizes two domains; required for efficient assembly of 30S; in Escherichia coli this protein has nuclease activity YP_002740094.1 identified by match to protein family HMM PF00561 YP_002740095.1 Essential for efficient processing of 16S rRNA YP_002740096.1 methylates guanosine-37 in various tRNAs; uses S-adenosyl-L-methionine to transfer methyl group to tRNA YP_002740097.1 identified by match to protein family HMM PF03477 YP_002740101.1 identified by match to protein family HMM PF02632 YP_002740102.1 catalyzes the reduction of 2 glutathione to glutathione disulfide; maintains high levels of reduced glutathione in the cytosol; involved in redox regulation and oxidative defense YP_002740103.1 identified by match to protein family HMM TIGR01730 YP_002740104.1 identified by match to protein family HMM PF00005 YP_002740105.1 identified by match to protein family HMM PF02687 YP_002740106.1 methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content YP_002740108.1 identified by match to protein family HMM PF03551 YP_002740110.1 identified by match to protein family HMM PF00248 YP_002740112.1 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis YP_002740113.1 identified by match to protein family HMM PF00293 YP_002740114.1 identified by match to protein family HMM PF00583 YP_002740116.1 identified by match to protein family HMM PF06171 YP_002740117.1 identified by match to protein family HMM PF01433 YP_002740118.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00486 YP_002740119.1 identified by match to protein family HMM PF00512; match to protein family HMM PF02518 YP_002740121.1 identified by match to protein family HMM PF01136 YP_002740122.1 unwinds DNA YP_002740123.1 identified by match to protein family HMM PF01098 YP_002740124.1 identified by match to protein family HMM PF01965; match to protein family HMM TIGR01383 YP_002740125.1 identified by match to protein family HMM PF00702; match to protein family HMM TIGR01549 YP_002740126.1 negatively supercoils closed circular double-stranded DNA YP_002740127.1 acts to negatively regulates ftsZ ring formation by modulating the frequency and position of the ftsZ ring formation YP_002740128.1 identified by match to protein family HMM PF05717 YP_002740129.1 identified by match to protein family HMM PF08860 YP_002740130.1 identified by match to protein family HMM PF00293 YP_002740131.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by match to protein family HMM PF01710 YP_002740133.1 identified by match to protein family HMM PF00004; match to protein family HMM PF02151; match to protein family HMM PF07724; match to protein family HMM PF07728 YP_002740134.1 identified by match to protein family HMM PF08796 YP_002740135.1 identified by match to protein family HMM PF00528; match to protein family HMM TIGR01726 YP_002740136.1 identified by match to protein family HMM PF00005 YP_002740137.1 catalyzes the formation of 5,10-methenyltetrahydrofolate from 5,10-methylenetetrahydrofolate and subsequent formation of 10-formyltetrahydrofolate from 5,10-methenyltetrahydrofolate YP_002740138.1 identified by match to protein family HMM PF01256; match to protein family HMM TIGR00196 YP_002740139.1 Catalyzes D-ribose 5-phosphate --> D-ribulose 5-phosphate in the nonoxidative branch of the pentose phosphate pathway YP_002740140.1 catalyzes the transfer of phosphate between the C1 and C5 carbons of pentose YP_002740141.1 identified by glimmer; putative YP_002740142.1 identified by glimmer; putative YP_002740143.1 catalyzes the formation of a purine and ribose phosphate from a purine nucleoside; in E. coli this enzyme functions in xanthosine degradation YP_002740144.1 identified by glimmer; putative YP_002740146.1 catalyzes the reversible phosphorolysis of ribonucleosides and 2'- deoxyribonucleosides to the free base and (2'-deoxy)ribose-1- phosphate YP_002740148.1 binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase YP_002740149.1 catalyzes the formation of (R)-4'-phosphopantothenate in coenzyme A biosynthesis YP_002740150.1 identified by glimmer; putative YP_002740151.1 identified by match to protein family HMM PF05175 YP_002740152.1 Catalyzes the reversible phosphorolysis of pyrimidines in the nucleotide synthesis salvage pathway YP_002740153.1 catalyzes the formation of D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-D-ribose-5-phosphate YP_002740154.1 Reclaims exogenous and endogenous cytidine and 2'-deoxycytidine molecules for UMP synthesis YP_002740155.1 identified by match to protein family HMM PF02608 YP_002740156.1 identified by match to protein family HMM PF00005 YP_002740157.1 identified by match to protein family HMM PF02653 YP_002740158.1 identified by match to protein family HMM PF02653 YP_002740159.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002740160.1 identified by match to protein family HMM PF00665 YP_002740161.1 involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsX YP_002740162.1 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling YP_002740163.1 identified by glimmer; putative YP_002740164.1 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling YP_002740165.1 catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids YP_002740167.1 identified by match to protein family HMM PF06149 YP_002740168.1 identified by match to protein family HMM PF06166 YP_002740169.1 catalyzes the removal of 5-oxoproline from various penultimate amino acid residues except L-proline YP_002740171.1 in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins YP_002740172.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002740173.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002740175.1 catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the tau chain serves as a scaffold to help in the dimerizaton of the alpha,epsilon and theta core complex; the gamma chain seems to interact with the delta and delta' subunits to transfer the beta subunit on the DNA YP_002740177.1 identified by match to protein family HMM PF00005; match to protein family HMM TIGR01978 YP_002740178.1 identified by match to protein family HMM PF01458; match to protein family HMM TIGR01981 YP_002740179.1 identified by match to protein family HMM PF00266; match to protein family HMM PF01212; match to protein family HMM TIGR01979 YP_002740180.1 identified by match to protein family HMM PF01592; match to protein family HMM TIGR01994 YP_002740181.1 identified by match to protein family HMM PF01458; match to protein family HMM TIGR01980 YP_002740182.1 identified by match to protein family HMM PF00144; match to protein family HMM PF00768; match to protein family HMM PF07943 YP_002740183.1 identified by match to protein family HMM PF01594 YP_002740184.1 identified by match to protein family HMM PF00455; match to protein family HMM PF08220; match to protein family HMM PF08279 YP_002740185.1 identified by match to protein family HMM PF00294; match to protein family HMM TIGR03168 YP_002740186.1 identified by match to protein family HMM PF00359; match to protein family HMM PF02378; match to protein family HMM PF02379; match to protein family HMM TIGR00829; match to protein family HMM TIGR00848; match to protein family HMM TIGR01427 YP_002740187.1 identified by match to protein family HMM PF01580 YP_002740189.1 identified by match to protein family HMM PF00266 YP_002740190.1 Required for the synthesis of the thiazole moiety YP_002740191.1 identified by match to protein family HMM PF00756 YP_002740193.1 identified by match to protein family HMM PF02384 YP_002740194.1 identified by match to protein family HMM PF01420 YP_002740196.1 identified by match to protein family HMM PF05012; match to protein family HMM TIGR01550 YP_002740197.1 identified by match to protein family HMM PF00589; match to protein family HMM PF02899 YP_002740198.1 identified by match to protein family HMM PF01420 YP_002740199.1 identified by match to protein family HMM PF00270; match to protein family HMM PF00271; match to protein family HMM PF04313; match to protein family HMM PF04851 YP_002740201.1 identified by match to protein family HMM PF01316; match to protein family HMM PF02863 YP_002740202.1 catalyzes the removal of N-terminal dipeptides when proline is the penultimate residue YP_002740203.1 Catalyzes DNA-template-directed extension of the 3'-end of a DNA strand by one nucleotide at a time. Proposed to be responsible for the synthesis of the lagging strand. In the low GC gram positive bacteria this enzyme is less processive and more error prone than its counterpart in other bacteria. YP_002740204.1 catalyzes the formation of D-fructose 1,6-bisphosphate from D-fructose 6-phosphate in glycolysis YP_002740205.1 catalyzes the formation of phosphoenolpyruvate from pyruvate YP_002740211.1 identified by match to protein family HMM PF09323 YP_002740212.1 identified by match to protein family HMM PF03773 YP_002740214.1 identified by match to protein family HMM PF08942 YP_002740215.1 identified by match to protein family HMM PF00575 YP_002740216.1 identified by match to protein family HMM PF03926 YP_002740217.1 identified by match to protein family HMM PF04024 YP_002740218.1 identified by match to protein family HMM PF00005 YP_002740219.1 identified by match to protein family HMM PF02687 YP_002740220.1 identified by match to protein family HMM PF01988 YP_002740222.1 identified by match to protein family HMM PF00266; match to protein family HMM PF01212; match to protein family HMM PF01276; match to protein family HMM PF03711 YP_002740223.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002740224.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002740225.1 identified by glimmer; putative YP_002740226.1 catalyzes the formation of spermidine from putrescine and S-adenosylmethioninamine YP_002740227.1 identified by match to protein family HMM PF03435 YP_002740228.1 identified by match to protein family HMM PF00278; match to protein family HMM TIGR01047 YP_002740229.1 catalyzes the formation of carbamoylputrescine from agmatine in the arginine decarboxylase pathway of putrescine biosynthesis YP_002740230.1 identified by match to protein family HMM PF00795; match to protein family HMM TIGR03381 YP_002740231.1 identified by match to protein family HMM PF00702; match to protein family HMM PF05116; match to protein family HMM PF08282; match to protein family HMM TIGR00099; match to protein family HMM TIGR01484 YP_002740233.1 identified by match to protein family HMM PF02517 YP_002740235.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466 YP_002740236.1 lipoprotein signal peptidase; integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis YP_002740237.1 identified by match to protein family HMM PF00849; match to protein family HMM PF01479; match to protein family HMM TIGR00005 YP_002740238.1 identified by match to protein family HMM PF00753; match to protein family HMM PF01473 YP_002740239.1 catalyzes the formation of glutamate 5-phosphate from glutamate in proline biosynthesis YP_002740240.1 Catalyzes the phosphorylation of L-glutamate during the proline biosynthesis pathway YP_002740241.1 identified by match to protein family HMM PF01210; match to protein family HMM PF03446; match to protein family HMM PF03807; match to protein family HMM TIGR00112 YP_002740242.1 catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to thymidine monophosphate (dTMP) to form thymidine diphosphate (dTDP) YP_002740243.1 catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the delta' subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA. YP_002740244.1 in Bacillus subtilis this protein is involved in the negative regulation of DNA replication initiation; interacts with DnaN and DnaA YP_002740245.1 identified by match to protein family HMM PF00590; match to protein family HMM TIGR00096 YP_002740246.1 identified by match to protein family HMM PF08020 YP_002740247.1 identified by match to protein family HMM PF06970 YP_002740248.1 TrmFO; Gid; glucose-inhibited division protein; similar to GidA; the gene from Bacillus subtilis encodes a tRNA-methyltransferase that utilizes folate as the carbon donor and bound flavin as reductant; modifies tRNA at position 54 (uridine) of the T-psi loop to form a C5-methyluridine YP_002740249.1 Catalyzes the phosphorylation of UMP to UDP YP_002740250.1 Rrf; Frr; ribosome-recycling factor; release factor 4; RF4; recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G; A GTPase-dependent process results in release of 50S from 70S; inhibited by release factor RF-1; essential for viability; structurally similar to tRNAs YP_002740252.1 identified by match to protein family HMM PF06855 YP_002740253.1 identified by match to protein family HMM PF02562 YP_002740254.1 identified by match to protein family HMM PF00583 YP_002740256.1 identified by match to protein family HMM PF00583 YP_002740257.1 identified by match to protein family HMM PF00633; match to protein family HMM TIGR00426; match to protein family HMM TIGR01259 YP_002740258.1 identified by match to protein family HMM PF03772; match to protein family HMM TIGR00360; match to protein family HMM TIGR00361 YP_002740260.1 identified by match to protein family HMM PF00005 YP_002740262.1 IF-3 has several functions that are required and promote translation initiation including; preventing association of 70S by binding to 30S; monitoring codon-anticodon interactions by promoting disassociation of fMet-tRNA(fMet) from initiation complexes formed on leaderless mRNAs or incorrectly bound noninitiatior tRNAs and complexes with noncanonical start sites; stimulates codon-anticodon interactions at P-site; involved in moving mRNA to the P-site; and in recycling subunits YP_002740263.1 identified by match to protein family HMM PF01632; match to protein family HMM TIGR00001 YP_002740264.1 binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit YP_002740265.1 identified by match to protein family HMM PF00903 YP_002740266.1 responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the pyrD subunit to the ultimate electron acceptor NAD(+) YP_002740267.1 catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway, using a flavin nucleotide as an essential cofactor; subclass 1B is a heterotetramer consisting of two PyrDB subunits, similar to the PyrDA subunits and two PyrK subunits YP_002740268.1 identified by match to protein family HMM PF01473; match to protein family HMM PF01832 YP_002740269.1 identified by match to protein family HMM PF05670; match to protein family HMM PF05833 YP_002740270.1 identified by match to protein family HMM PF02130; match to protein family HMM TIGR00043 YP_002740271.1 identified by match to protein family HMM PF01219 YP_002740272.1 Era; Escherichia coli Ras-like protein; Bex; Bacillus Era-complementing segment; essential protein in Escherichia coli that is involved in many cellular processes; GTPase; binds the cell membrane through apparent C-terminal domain; mutants are arrested during the cell cycle; Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome YP_002740273.1 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases YP_002740274.1 catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; involved in coenzyme A biosynthesis YP_002740275.1 identified by match to protein family HMM PF07690 YP_002740276.1 in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif YP_002740277.1 identified by match to protein family HMM PF03840; match to protein family HMM TIGR00810 YP_002740278.1 identified by match to protein family HMM PF00575; match to protein family HMM PF00773; match to protein family HMM PF08206; match to protein family HMM TIGR00358; match to protein family HMM TIGR02063 YP_002740279.1 binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation YP_002740280.1 with TehA confers resistance to tellurite YP_002740281.1 identified by match to protein family HMM PF06054 YP_002740282.1 identified by match to protein family HMM PF01432; match to protein family HMM PF08439; match to protein family HMM TIGR00181 YP_002740283.1 identified by match to protein family HMM PF01596; match to protein family HMM PF08241 YP_002740284.1 cis/trans isomerase of peptidylprolyl; PPIase; membrane-bound lipoprotein YP_002740287.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002740288.1 identified by match to protein family HMM PF00300 YP_002740289.1 identified by match to protein family HMM PF04073 YP_002740290.1 identified by match to protein family HMM PF04018 YP_002740291.1 identified by match to protein family HMM PF01183 YP_002740292.1 forms a homotrimer; catalyzes the acetylation of glucosamine-1-phosphate and uridylation of N-acetylglucosamine-1-phosphate to produce UDP-GlcNAc; function in cell wall synthesis YP_002740293.1 identified by match to protein family HMM PF00293 YP_002740295.1 enables the cleavage of the glycosidic bond in both 5'-methylthioadenosine and S-adenosylhomocysteine YP_002740296.1 identified by match to protein family HMM PF04394 YP_002740297.1 3'-5' exonuclease of DNA polymerase III YP_002740298.1 identified by match to protein family HMM PF03009 YP_002740299.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by match to protein family HMM PF01710 YP_002740302.1 identified by match to protein family HMM PF02683 YP_002740303.1 identified by match to protein family HMM PF00578; match to protein family HMM PF08534 YP_002740304.1 identified by match to protein family HMM PF00324 YP_002740305.1 identified by match to protein family HMM PF01297 YP_002740306.1 identified by match to protein family HMM PF04270; match to protein family HMM TIGR01363 YP_002740307.1 identified by match to protein family HMM PF04270; match to protein family HMM TIGR01363 YP_002740308.1 identified by match to protein family HMM PF04270 YP_002740310.1 catalyzes the release of the N-terminal amino acid from a tripeptide YP_002740311.1 identified by match to protein family HMM PF00762; match to protein family HMM TIGR00109 YP_002740312.1 identified by match to protein family HMM PF01741; match to protein family HMM TIGR00220 YP_002740313.1 identified by match to protein family HMM PF04138 YP_002740314.1 identified by match to protein family HMM PF06177 YP_002740315.1 catalyzes the formation of 4-aspartyl phosphate from aspartate 4-semialdehyde YP_002740316.1 catalyzes the formation of dihydrodipicolinate from L-aspartate 4-semialdehyde and pyruvate in lysine and diaminopimelate biosynthesis YP_002740317.1 in Escherichia coli this protein is involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2-thiouridine, which is found in the wobble position of some tRNAs and affects ribosomal frameshifting; shows potassium-dependent dimerization and GTP hydrolysis; also involved in regulation of glutamate-dependent acid resistance and activation of gadE YP_002740318.1 4-OT; member of subfamily 5; forms a dimer; the function in the Escherichia coli cell is unknown YP_002740319.1 catalyzes the formation of thymidine 5'-phosphate from thymidine YP_002740320.1 identified by match to protein family HMM PF00583 YP_002740321.1 recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2 YP_002740322.1 identified by match to protein family HMM PF05175; match to protein family HMM PF08241; match to protein family HMM PF08242; match to protein family HMM TIGR00536; match to protein family HMM TIGR03387 YP_002740323.1 identified by match to protein family HMM PF01300; match to protein family HMM TIGR00057 YP_002740324.1 identified by match to protein family HMM PF00583 YP_002740325.1 catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate YP_002740328.1 identified by match to protein family HMM PF06207 YP_002740329.1 identified by match to protein family HMM PF01938; match to protein family HMM PF05958; match to protein family HMM TIGR00479 YP_002740332.1 identified by match to protein family HMM PF06970 YP_002740333.1 identified by match to protein family HMM PF00145; match to protein family HMM TIGR00675 YP_002740337.1 identified by match to protein family HMM PF02517 YP_002740339.1 identified by match to protein family HMM PF02534 YP_002740343.1 identified by match to protein family HMM PF05257 YP_002740345.1 identified by match to protein family HMM PF08843 YP_002740347.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by match to protein family HMM PF00665 YP_002740348.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by match to protein family HMM PF01609 YP_002740349.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002740352.1 identified by match to protein family HMM PF00302 YP_002740353.1 methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content YP_002740355.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002740356.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by match to protein family HMM PF01609 YP_002740358.1 identified by match to protein family HMM PF00005 YP_002740359.1 identified by match to protein family HMM PF06182 YP_002740360.1 identified by match to protein family HMM PF01381 YP_002740361.1 identified by glimmer; putative YP_002740364.1 identified by glimmer; putative YP_002740365.1 identified by match to protein family HMM PF01497 YP_002740366.1 identified by match to protein family HMM PF01032 YP_002740367.1 identified by match to protein family HMM PF01032 YP_002740368.1 identified by match to protein family HMM PF00005 YP_002740369.1 identified by match to protein family HMM PF07674 YP_002740372.1 Low similarity to site-specific recombinase; identified by match to protein family HMM PF00239; match to protein family HMM PF07508 YP_002740376.1 identified by match to protein family HMM PF03747 YP_002740377.1 identified by match to protein family HMM PF00781; match to protein family HMM TIGR00147 YP_002740378.1 identified by match to protein family HMM PF00128; match to protein family HMM PF02903 YP_002740381.1 identified by match to protein family HMM PF01381 YP_002740382.1 identified by match to protein family HMM PF06414 YP_002740385.1 identified by match to protein family HMM PF05713 YP_002740386.1 identified by match to protein family HMM PF01820; match to protein family HMM PF07478; match to protein family HMM TIGR01205 YP_002740388.1 identified by match to protein family HMM PF00583 YP_002740389.1 identified by glimmer; putative YP_002740390.1 identified by match to protein family HMM PF01098 YP_002740391.1 catalyzes the formation of oxaloacetate from phosphoenolpyruvate YP_002740392.1 identified by match to protein family HMM PF04392 YP_002740393.1 identified by match to protein family HMM PF02653 YP_002740394.1 identified by match to protein family HMM PF00005 YP_002740395.1 synthesizes RNA primers at the replication forks YP_002740396.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; primary sigma factor of bacterium YP_002740397.1 identified by match to protein family HMM PF01883 YP_002740398.1 identified by match to protein family HMM PF00534 YP_002740399.1 identified by match to protein family HMM PF00534 YP_002740400.1 identified by match to protein family HMM PF04024 YP_002740402.1 essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication YP_002740404.1 adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active YP_002740405.1 identified by match to protein family HMM PF00583 YP_002740406.1 identified by match to protein family HMM PF00571; match to protein family HMM PF07085; match to protein family HMM PF08279 YP_002740407.1 catalyzes the removal of N-terminal amino acids from peptides and arylamides YP_002740408.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002740409.1 identified by match to protein family HMM PF01609 YP_002740410.1 identified by match to protein family HMM PF00580; match to protein family HMM TIGR01073 YP_002740411.1 Involved in DNA double-strand break repair and recombination. Promotes the annealing of complementary single-stranded DNA and by simulation of RAD51 recombinase YP_002740412.1 identified by match to protein family HMM PF00117; match to protein family HMM PF07722 YP_002740413.1 modulates transcription in response to the NADH/NAD(+) redox state YP_002740415.1 identified by match to protein family HMM PF08866 YP_002740416.1 identified by match to protein family HMM PF00266 YP_002740417.1 catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP YP_002740418.1 identified by match to protein family HMM PF01928 YP_002740419.1 identified by match to protein family HMM PF04607 YP_002740420.1 catalyzes the phosphorylation of NAD to NADP YP_002740421.1 identified by match to protein family HMM PF00849; match to protein family HMM TIGR00005 YP_002740422.1 in Salmonella this enzyme is required for ethanolamine catabolism; has higher affinity for CoA than Pta YP_002740423.1 identified by match to protein family HMM PF02575; match to protein family HMM TIGR00103 YP_002740424.1 identified by match to protein family HMM PF06912 YP_002740425.1 identified by match to protein family HMM PF00829; match to protein family HMM TIGR00061 YP_002740426.1 identified by match to protein family HMM PF04327 YP_002740427.1 involved in the peptidyltransferase reaction during translation YP_002740430.1 catalyzes the formation of FMN from riboflavin and the formation of FAD from FMN; in Bacillus the ribC gene has both flavokinase and FAD synthetase activities YP_002740431.1 identified by match to protein family HMM PF02588 YP_002740432.1 identified by match to protein family HMM PF02645; match to protein family HMM TIGR00762 YP_002740433.1 identified by match to protein family HMM PF00216 YP_002740434.1 identified by match to protein family HMM PF00005 YP_002740435.1 identified by match to protein family HMM TIGR01716 YP_002740436.1 identified by match to protein family HMM PF07690 YP_002740437.1 this protein catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction; essential for DNA replication and repair of damaged DNA; similar to ligase LigB YP_002740438.1 identified by match to protein family HMM PF00128; match to protein family HMM PF02922; match to protein family HMM TIGR02104 YP_002740439.1 identified by match to protein family HMM PF00171 YP_002740440.1 catalyzes the transfer of a segment of a 1,4-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain YP_002740441.1 catalyzes the formation of ADP-glucose and diphosphate from ATP and alpha-D-glucose 1-phosphate YP_002740442.1 identified by match to protein family HMM PF00483; match to protein family HMM TIGR02092 YP_002740443.1 catalyzes the formation of alpha-1,4-glucan chains from ADP-glucose YP_002740444.1 identified by match to protein family HMM PF02595; match to protein family HMM TIGR00045 YP_002740445.1 identified by match to protein family HMM PF07997 YP_002740446.1 enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis YP_002740447.1 identified by glimmer; putative YP_002740448.1 identified by match to protein family HMM PF01710 YP_002740449.1 identified by match to protein family HMM TIGR02774 YP_002740450.1 identified by match to protein family HMM PF00580; match to protein family HMM TIGR02785 YP_002740452.1 identified by match to protein family HMM PF00746; match to protein family HMM PF04650; match to protein family HMM PF05342; match to protein family HMM PF07501; match to protein family HMM PF07580; match to protein family HMM PF07581; match to protein family HMM TIGR01167; match to protein family HMM TIGR01168 YP_002740453.1 essential GTPase; functions in ribosome assembly; binds a unique part of the 23S rRNA; interacts with ribosomal protein L25(Ctc) YP_002740454.1 RNH2; RNase HII; binds manganese; endonuclease which specifically degrades the RNA of RNA-DNA hybrids YP_002740455.1 identified by match to protein family HMM PF00654; match to protein family HMM PF02080 YP_002740456.1 site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; cell division protein FtsK may regulate the XerS YP_002740457.1 identified by match to protein family HMM PF03099; match to protein family HMM TIGR00545 YP_002740458.1 identified by match to protein family HMM PF00070; match to protein family HMM PF00364; match to protein family HMM PF01134; match to protein family HMM PF02852; match to protein family HMM PF03486; match to protein family HMM PF07992; match to protein family HMM TIGR01350 YP_002740459.1 unlike PdhC proteins from other organisms, some Mycoplasma lack an N-terminal lipoyl domain; in Mycoplasma hyopneumonia the PdhD proteins contains the lipoyl domain YP_002740460.1 identified by match to protein family HMM PF02779; match to protein family HMM PF02780 YP_002740461.1 identified by match to protein family HMM PF00676 YP_002740462.1 identified by match to protein family HMM PF01554; match to protein family HMM TIGR00797 YP_002740463.1 catalyzes the formation of N-carbamoyl-L-aspartate from (S)-dihydroorotate in pyrimidine biosynthesis YP_002740464.1 identified by match to protein family HMM PF00293 YP_002740465.1 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine YP_002740467.1 identified by match to protein family HMM PF00702; match to protein family HMM TIGR01549; match to protein family HMM TIGR02254 YP_002740468.1 identified by match to protein family HMM PF08867 YP_002740470.1 identified by glimmer; putative YP_002740471.1 identified by match to protein family HMM PF04270; match to protein family HMM TIGR01363 YP_002740472.1 identified by match to protein family HMM PF04270; match to protein family HMM TIGR01363 YP_002740473.1 identified by glimmer; putative YP_002740474.1 identified by match to protein family HMM PF00391; match to protein family HMM PF02896; match to protein family HMM PF05524; match to protein family HMM TIGR01417 YP_002740475.1 identified by match to protein family HMM PF00381; match to protein family HMM TIGR01003 YP_002740476.1 identified by match to protein family HMM PF00462; match to protein family HMM TIGR02194 YP_002740477.1 Catalyzes the rate-limiting step in dNTP synthesis YP_002740478.1 B2 or R2 protein; type 1b enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdE YP_002740479.1 identified by match to protein family HMM PF00455; match to protein family HMM PF08220; match to protein family HMM PF08279 YP_002740481.1 catalyzes the formation of 6-phospho-galactose from a 6-phospho-beta-galactoside YP_002740482.1 identified by match to protein family HMM PF02302; match to protein family HMM PF02378; match to protein family HMM TIGR00394; match to protein family HMM TIGR00410; match to protein family HMM TIGR00853 YP_002740483.1 identified by match to protein family HMM PF02255; match to protein family HMM TIGR00823 YP_002740484.1 identified by match to protein family HMM PF00874; match to protein family HMM PF03123 YP_002740485.1 catalyzes the reversible reaction of dihydroxyacetone phosphate with glyceraldehyde 3-phosphate to produce tagatose 1,6-bisphosphate; in Streptococcus pyogenes there are two paralogs of tagatose-bisphosphate aldolase, encoded by lacD1 and lacD2; expression of lacD1 is highly regulated by environmental conditions while lacD2 specializes in an efficient utilization of carbohydrate sources YP_002740486.1 catalyzes the formation of tagatose 1,6-bisphosphate from tagatose 6-phosphate and ATP YP_002740487.1 catalyzes the interconversion of galactose 6-phosphate to tagatose 6-phosphate YP_002740488.1 catalyzes the interconversion of galactose 6-phosphate to tagatose 6-phosphate; tagatose pathway for galactose utilization YP_002740489.1 identified by glimmer; putative YP_002740490.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002740491.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002740495.1 binds to the ribosome on the universally-conserved alpha-sarcin loop YP_002740496.1 identified by match to protein family HMM PF00149 YP_002740497.1 identified by match to protein family HMM PF02463; match to protein family HMM TIGR00634 YP_002740498.1 identified by match to protein family HMM PF01316; match to protein family HMM PF02863 YP_002740499.1 identified by match to protein family HMM PF01479; match to protein family HMM PF01728; match to protein family HMM TIGR00478 YP_002740500.1 identified by match to protein family HMM PF00348 YP_002740501.1 catalyzes the bidirectional exonucleolytic cleavage of DNA YP_002740502.1 bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides YP_002740503.1 functions in pyrimidine salvage; pyrimidine ribonucleoside kinase; phosphorylates nucleosides or dinucleosides to make UMP or CMP using ATP or GTP as the donor YP_002740505.1 catalyzes isomerization of specific uridines in RNA to pseudouridine; responsible for residues in T loops of many tRNAs YP_002740507.1 identified by match to protein family HMM PF01053; match to protein family HMM PF01212 YP_002740509.1 identified by match to protein family HMM PF01226 YP_002740510.1 identified by match to protein family HMM PF04203; match to protein family HMM TIGR01076 YP_002740511.1 negatively supercoils closed circular double-stranded DNA YP_002740512.1 Converts (S)-lactate and NAD(+) to pyruvate and NADH YP_002740513.1 identified by match to protein family HMM PF00520; match to protein family HMM PF07885 YP_002740514.1 identified by match to protein family HMM PF05016; match to protein family HMM TIGR02385 YP_002740516.1 identified by match to protein family HMM PF00753 YP_002740517.1 identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF00989; match to protein family HMM PF02518; match to protein family HMM TIGR00229 YP_002740518.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00486 YP_002740519.1 identified by match to protein family HMM PF00633; match to protein family HMM PF00730; match to protein family HMM TIGR01084 YP_002740520.1 catalyzes the formation of 10-formyltetrahydrofolate from formate and tetrahydrofolate YP_002740521.1 identified by match to protein family HMM PF04127; match to protein family HMM TIGR02114 YP_002740522.1 decarboxylates 4-phosphopantothenoylcysteine to form 4'-phosphopantotheine. YP_002740525.1 identified by match to protein family HMM PF02829; match to protein family HMM PF08279 YP_002740528.1 identified by match to protein family HMM PF05717 YP_002740531.1 identified by match to protein family HMM PF00512; match to protein family HMM PF02518 YP_002740532.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00486 YP_002740535.1 identified by match to protein family HMM PF00005 YP_002740536.1 identified by match to protein family HMM PF00005; match to protein family HMM PF00664 YP_002740537.1 identified by glimmer; putative YP_002740538.1 identified by match to protein family HMM PF00733 YP_002740539.1 identified by glimmer; putative YP_002740541.1 identified by match to protein family HMM PF00583 YP_002740543.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion YP_002740544.1 identified by match to protein family HMM PF02517 YP_002740545.1 identified by match to protein family HMM PF00497; match to protein family HMM PF00528; match to protein family HMM TIGR01726 YP_002740546.1 identified by match to protein family HMM PF00005 YP_002740547.1 catalyzes the formation of D-glucono-1,5-lactone 6-phosphate from D-glucose 6-phosphate YP_002740548.1 identified by match to protein family HMM PF00448; match to protein family HMM PF02881; match to protein family HMM TIGR00064 YP_002740549.1 identified by match to protein family HMM PF00702; match to protein family HMM PF05116; match to protein family HMM PF08282; match to protein family HMM TIGR00099; match to protein family HMM TIGR01484 YP_002740550.1 identified by match to protein family HMM PF05116; match to protein family HMM PF08282; match to protein family HMM TIGR00099; match to protein family HMM TIGR01484 YP_002740551.1 identified by match to protein family HMM PF02463; match to protein family HMM PF06470; match to protein family HMM TIGR02168 YP_002740552.1 cytoplasmic enzyme involved in processing rRNA and some mRNAs; substrates typically have dsRNA regions; forms a homodimer; have N-terminal nuclease and C-terminal RNA-binding domains; requires magnesium as preferred ion for activity YP_002740553.1 identified by match to protein family HMM PF00478; match to protein family HMM TIGR01306 YP_002740556.1 identified by glimmer; putative YP_002740557.1 identified by glimmer; putative YP_002740558.1 identified by glimmer; putative YP_002740560.1 identified by match to protein family HMM PF06961 YP_002740561.1 catalyzes the oxidation of 3-isopropylmalate to 3-carboxy-4-methyl-2-oxopentanoate in leucine biosynthesis YP_002740562.1 identified by match to protein family HMM PF08502 YP_002740563.1 identified by match to protein family HMM PF00682 YP_002740564.1 identified by match to protein family HMM PF04237 YP_002740565.1 identified by match to protein family HMM PF03932 YP_002740566.1 identified by match to protein family HMM PF04304 YP_002740567.1 catalyzes the ATP-dependent breakage of single-stranded DNA followed by passage and rejoining, maintains net negative superhelicity YP_002740568.1 identified by match to protein family HMM PF04087 YP_002740570.1 identified by match to protein family HMM PF02481; match to protein family HMM TIGR00732 YP_002740571.1 identified by match to protein family HMM PF00483 YP_002740572.1 identified by match to protein family HMM PF00892 YP_002740573.1 identified by match to protein family HMM PF01633; match to protein family HMM PF01636 YP_002740574.1 identified by match to protein family HMM PF08240 YP_002740575.1 4-diphosphocytidyl-2C-methyl-D-erythritol synthase; MEP cytidylyltransferase; MCT; catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate; involved in isoprenoid and isopentenyl-PP biosynthesis; forms homodimers YP_002740576.1 identified by match to protein family HMM PF01943; match to protein family HMM PF03023 YP_002740577.1 required for phosphorylcholine incorporation in teichoic and lipoteichoic acids; identified by match to protein family HMM PF04991 YP_002740578.1 identified by match to protein family HMM PF04991 YP_002740579.1 four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate; CarB is responsible for the amidotransferase activity YP_002740580.1 catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers YP_002740581.1 catalyzes the transfer of the carbamoyl moiety from carbamoyl phosphate to L- aspartate in pyrimidine biosynthesis YP_002740582.1 regulates pyrimidine biosynthesis by binding to the mRNA of the pyr genes, also has been shown to have uracil phosphoribosyltransferase activity YP_002740583.1 identified by match to protein family HMM PF00633; match to protein family HMM PF00730; match to protein family HMM TIGR01083 YP_002740584.1 identified by match to protein family HMM PF02620 YP_002740586.1 identified by match to protein family HMM PF00005 YP_002740587.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002740588.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by match to protein family HMM PF01610 YP_002740589.1 putative metalloprotease YP_002740590.1 identified by match to protein family HMM PF04011 YP_002740591.1 glucose-inhibited division protein B; SAM-dependent methyltransferase; methylates the N7 position of guanosine in position 527 of 16S rRNA YP_002740592.1 identified by match to protein family HMM PF00860; match to protein family HMM TIGR00801 YP_002740593.1 identified by match to protein family HMM PF00448; match to protein family HMM PF02881; match to protein family HMM PF02978; match to protein family HMM TIGR00959 YP_002740594.1 identified by match to protein family HMM PF04297; match to protein family HMM PF04967; match to protein family HMM PF08281 YP_002740595.1 identified by match to protein family HMM PF09148 YP_002740596.1 identified by match to protein family HMM PF01966 YP_002740597.1 identified by match to protein family HMM PF00702; match to protein family HMM PF05116; match to protein family HMM PF08282; match to protein family HMM TIGR00099; match to protein family HMM TIGR01484 YP_002740598.1 this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site YP_002740599.1 may be involved in chromosome condensation; overexpression in Escherichia coli protects against decondensation by camphor; overexpressing the protein results in an increase in supercoiling YP_002740600.1 may be involved in chromosome condensation; overexpression in Escherichia coli protects against decondensation by camphor; overexpressing the protein results in an increase in supercoiling YP_002740601.1 identified by match to protein family HMM PF01817; match to protein family HMM TIGR01805 YP_002740602.1 An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group YP_002740603.1 identified by match to protein family HMM PF01368; match to protein family HMM PF02272 YP_002740604.1 RpmE2; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster do not have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome YP_002740607.1 converts 2-oxoglutarate to glutamate; in Escherichia coli this enzyme plays a role in glutamate synthesis when the cell is under energy restriction; uses NADPH; forms a homohexamer YP_002740609.1 identified by match to protein family HMM PF00005 YP_002740610.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002740612.1 identified by match to protein family HMM PF00701 YP_002740613.1 identified by match to protein family HMM PF00383; match to protein family HMM TIGR01354 YP_002740614.1 identified by match to protein family HMM PF04608 YP_002740616.1 identified by match to protein family HMM PF00005; match to protein family HMM PF08352; match to protein family HMM TIGR01727 YP_002740619.1 identified by match to protein family HMM PF00005 YP_002740620.1 identified by match to protein family HMM PF00005; match to protein family HMM PF00664 YP_002740621.1 identified by match to protein family HMM PF00326 YP_002740622.1 identified by match to protein family HMM PF05147 YP_002740624.1 identified by match to protein family HMM PF02517 YP_002740628.1 identified by match to protein family HMM PF06970 YP_002740630.1 present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulates GTPase activity of translation factors YP_002740631.1 binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit YP_002740632.1 identified by glimmer; putative YP_002740633.1 identified by match to protein family HMM PF01979; match to protein family HMM PF07969 YP_002740634.1 identified by match to protein family HMM PF00005; match to protein family HMM PF00664 YP_002740635.1 identified by match to protein family HMM PF00005; match to protein family HMM PF00664 YP_002740636.1 identified by match to protein family HMM PF01625; match to protein family HMM PF01641; match to protein family HMM TIGR00357; match to protein family HMM TIGR00401 YP_002740637.1 catalyzes the formation of O-phospho-L-homoserine from L-homoserine in threonine biosynthesis from asparate YP_002740638.1 catalyzes the formation of L-aspartate 4-semialdehyde from L-homoserine YP_002740639.1 enables recognition and targeting of proteins for proteolysis, involved in negative regulation of competence YP_002740642.1 identified by match to protein family HMM PF00535 YP_002740643.1 identified by match to protein family HMM PF00534 YP_002740644.1 identified by match to protein family HMM PF04991 YP_002740645.1 identified by match to protein family HMM PF03816; match to protein family HMM TIGR00350 YP_002740646.1 catalyzes the formation of phenylpyruvate from prephenate in phenylalanine biosynthesis YP_002740647.1 identified by match to protein family HMM PF01202 YP_002740648.1 catalyzes the formation of 5-O-(1-carboxyvinyl)-3-phosphoshikimate from phosphoenolpyruvate and 3-phosphoshikimate in tryptophan biosynthesis YP_002740649.1 identified by match to protein family HMM PF06133 YP_002740650.1 catalyzes the formation of 4-hydroxyphenylpyruvate from prephenate YP_002740651.1 catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis YP_002740652.1 catalyzes the formation of 3-dehydroquinate from 3-deoxy-arabino-heptulonate 7-phosphate; functions in aromatic amino acid biosynthesis YP_002740653.1 AroE; catalyzes the conversion of shikimate to 3-dehydroshikimate YP_002740654.1 catalyzes the dehydration of 3-dehydroquinate to form 3-dehydroshikimate in aromatic amino acid biosynthesis YP_002740657.1 identified by match to protein family HMM PF00005 YP_002740658.1 converts 1,4-alpha-D-glucans to maltodextrin YP_002740659.1 Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_002740660.1 identified by match to protein family HMM PF04525 YP_002740662.1 identified by match to protein family HMM PF01547 YP_002740663.1 identified by match to protein family HMM PF00528 YP_002740664.1 identified by match to protein family HMM PF00528 YP_002740665.1 identified by match to protein family HMM PF00005; match to protein family HMM PF08402 YP_002740666.1 catalyzes the reduction of UDP-N-acetylglucosamine enolpyruvate to form UDP-N-acetylmuramate in peptidoglycan biosynthesis YP_002740667.1 identified by match to protein family HMM PF03306; match to protein family HMM TIGR01252 YP_002740668.1 identified by match to protein family HMM PF00392 YP_002740669.1 identified by match to protein family HMM PF00497 YP_002740670.1 identified by match to protein family HMM PF01895; match to protein family HMM TIGR02135 YP_002740671.1 ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation YP_002740672.1 ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation YP_002740673.1 identified by match to protein family HMM PF00528; match to protein family HMM TIGR00974 YP_002740674.1 identified by match to protein family HMM PF00528; match to protein family HMM TIGR02138 YP_002740675.1 identified by match to protein family HMM PF01547; match to protein family HMM TIGR02136 YP_002740677.1 identified by match to protein family HMM PF01189 YP_002740678.1 identified by match to protein family HMM PF00459 YP_002740679.1 identified by match to protein family HMM PF05256 YP_002740680.1 the anti-alpha factor Spx interacts with RNA polymerase alpha subunit C-terminal domain in a region that interacts with the sigma 70 subunit and may interfere with activation of promoters; in Bacillus subtilis this protein is a substrate for ClpXP protease; blocks transcription of the competence regulatory gene encoded by the srf operon; regulates a number of genes involved in thiol homeostasis including trxA and trxB; monomeric member of ArsC family of proteins; does not bind DNA; contains a disulfide bond between C10 and C13 which may sense disulfide stress YP_002740681.1 identified by match to protein family HMM PF07314; match to protein family HMM TIGR01906 YP_002740682.1 identified by match to protein family HMM PF00702; match to protein family HMM TIGR01457; match to protein family HMM TIGR01460 YP_002740683.1 identified by match to protein family HMM PF01643 YP_002740684.1 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III YP_002740686.1 identified by match to protein family HMM PF06103 YP_002740687.1 transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein YP_002740688.1 catalyzes the phosphorylation of the phosphocarrier protein HPr of the bacterial phosphotransferase system YP_002740689.1 a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA YP_002740690.1 identified by match to protein family HMM PF01182 YP_002740691.1 Synthesizes oQ from preQ1 in a single S-adenosylmethionine-requiring step YP_002740692.1 identified by match to protein family HMM PF01473 YP_002740693.1 identified by match to protein family HMM PF00583 YP_002740694.1 catalyzes the formation of nicotinamide adenine dinucleotide (NAD) from nicotinic acid adenine dinucleotide (NAAD) using either ammonia or glutamine as the amide donor and ATP; ammonia-utilizing enzymes include the ones from Bacillus and Escherichia coli while glutamine-utilizing enzymes include the Mycobacterial one; forms homodimers YP_002740695.1 catalyzes the formation of 5-phospho-alpha-D-ribose 1-diphosphate and nicotinate from nicotinate D-ribonucleotide and diphosphate YP_002740697.1 identified by match to protein family HMM PF01381 YP_002740700.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002740701.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by match to protein family HMM PF01609 YP_002740703.1 identified by match to protein family HMM PF01136 YP_002740705.1 identified by match to protein family HMM PF01136 YP_002740708.1 identified by match to protein family HMM PF01555 YP_002740710.1 identified by match to protein family HMM PF00165 YP_002740711.1 identified by match to protein family HMM PF00005 YP_002740712.1 identified by match to protein family HMM PF00005 YP_002740713.1 identified by match to protein family HMM TIGR02185 YP_002740714.1 identified by match to protein family HMM PF02361 YP_002740715.1 identified by match to protein family HMM PF00005 YP_002740716.1 identified by match to protein family HMM PF05717 YP_002740718.1 contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway YP_002740719.1 identified by match to protein family HMM PF00392; match to protein family HMM PF07702 YP_002740720.1 identified by match to protein family HMM PF00892 YP_002740721.1 identified by match to protein family HMM PF00144 YP_002740723.1 identified by match to protein family HMM PF00657 YP_002740724.1 identified by match to protein family HMM PF00702; match to protein family HMM PF05116; match to protein family HMM PF08282; match to protein family HMM TIGR00099; match to protein family HMM TIGR01484 YP_002740727.1 cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+) YP_002740728.1 identified by match to protein family HMM PF00588; match to protein family HMM PF08032; match to protein family HMM TIGR00186 YP_002740729.1 identified by match to protein family HMM PF00070; match to protein family HMM PF01134; match to protein family HMM PF03486; match to protein family HMM PF07992; match to protein family HMM TIGR01292 YP_002740731.1 identified by match to protein family HMM PF00005 YP_002740732.1 identified by match to protein family HMM PF00528; match to protein family HMM TIGR01726 YP_002740733.1 identified by match to protein family HMM PF03960; match to protein family HMM TIGR01617 YP_002740734.1 identified by match to protein family HMM PF01035; match to protein family HMM TIGR00589 YP_002740735.1 identified by match to protein family HMM PF00583 YP_002740736.1 identified by match to protein family HMM PF08876 YP_002740737.1 identified by match to protein family HMM PF03006; match to protein family HMM TIGR01065 YP_002740738.1 with PdxST is involved in the biosynthesis of pyridoxal 5'-phosphate; PdxT catalyzes the hydrolysis of glutamine to glutamate and ammonia; PdxS utilizes the ammonia to synthesize pyridoxal 5'-phosphate YP_002740739.1 with PdxT forms pyridoxal 5'-phosphate from glutamine, either ribose 5-phosphate or ribulose 5-phosphate, and either glyceraldehyde 3-phosphate or dihydroxyacetone phosphate YP_002740740.1 identified by match to protein family HMM PF00070; match to protein family HMM PF02852; match to protein family HMM PF07992 YP_002740742.1 identified by match to protein family HMM PF02424 YP_002740743.1 identified by match to protein family HMM PF03358 YP_002740744.1 identified by match to protein family HMM PF03358 YP_002740745.1 identified by match to protein family HMM PF05979 YP_002740746.1 glycine--tRNA ligase beta chain; glyS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA YP_002740747.1 glycine--tRNA ligase alpha chain; GlyRS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA YP_002740749.1 identified by match to protein family HMM PF00248 YP_002740750.1 identified by match to protein family HMM PF01522 YP_002740752.1 identified by match to protein family HMM PF01118; match to protein family HMM PF01408 YP_002740753.1 identified by match to protein family HMM PF00270; match to protein family HMM PF00271 YP_002740756.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002740757.1 EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu YP_002740758.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by match to protein family HMM PF01609 YP_002740759.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002740760.1 identified by match to protein family HMM PF00230 YP_002740761.1 identified by match to protein family HMM PF00746; match to protein family HMM PF06458; match to protein family HMM TIGR01167 YP_002740764.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002740765.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002740766.1 identified by match to protein family HMM PF00408; match to protein family HMM PF02878; match to protein family HMM PF02879; match to protein family HMM PF02880 YP_002740767.1 identified by match to protein family HMM TIGR01295 YP_002740768.1 identified by match to protein family HMM PF00497 YP_002740769.1 identified by match to protein family HMM PF00005 YP_002740770.1 identified by match to protein family HMM PF00528; match to protein family HMM TIGR01726 YP_002740771.1 identified by match to protein family HMM PF00515; match to protein family HMM PF07719 YP_002740772.1 identified by match to protein family HMM PF01594 YP_002740774.1 part of catalytic core of ATP synthase; alpha(3)beta(3)gamma(1)delta(1)epsilon(1); involved in producing ATP from ADP in the presence of the proton motive force across the membrane YP_002740775.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit YP_002740776.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is a regulatory subunit YP_002740777.1 produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit YP_002740778.1 Produces ATP from ADP in the presence of a proton gradient across the membrane; the delta subunit is part of the catalytic core of the ATP synthase complex YP_002740779.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit B is part of the membrane proton channel. YP_002740780.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0 YP_002740781.1 produces ATP from ADP in the presence of a proton gradient across the membrane; subunit C is part of the membrane proton channel F0 YP_002740784.1 necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus YP_002740785.1 identified by match to protein family HMM PF02618; match to protein family HMM TIGR00247 YP_002740786.1 identified by match to protein family HMM PF00583 YP_002740787.1 identified by match to protein family HMM PF00583 YP_002740788.1 Catalyzes the formation of UDP-N-acetylmuramoyl-L-alanine from UDP-N-acetylmuramate and L-alanine in peptidoglycan synthesis YP_002740790.1 identified by match to protein family HMM PF00176; match to protein family HMM PF00271; match to protein family HMM PF04434; match to protein family HMM PF08455 YP_002740791.1 identified by match to protein family HMM PF00155 YP_002740792.1 catalyzes the formation of cystathionine from L-cysteine and O-succinyl-L-homoserine YP_002740793.1 identified by match to protein family HMM PF00496 YP_002740794.1 identified by match to protein family HMM PF01943; match to protein family HMM PF03023 YP_002740795.1 involved in cell wall formation; peptidoglycan synthesis; cytoplasmic enzyme; catalyzes the addition of lysine to UDP-N-acetylmuramoyl-L-alanyl-D-glutamate forming UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysine YP_002740796.1 identified by match to protein family HMM PF05532 YP_002740797.1 identified by match to protein family HMM PF08820 YP_002740799.1 catalyzes the hydrolysis of pyrophosphate to phosphate YP_002740800.1 identified by match to protein family HMM PF01541 YP_002740801.1 identified by match to protein family HMM PF05175 YP_002740802.1 identified by match to protein family HMM PF00575 YP_002740803.1 identified by match to protein family HMM PF00160; match to protein family HMM PF00702; match to protein family HMM PF05116; match to protein family HMM PF08282; match to protein family HMM TIGR00099; match to protein family HMM TIGR01484 YP_002740804.1 binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit YP_002740805.1 binds to single stranded DNA and may facilitate the binding and interaction of other proteins to DNA YP_002740806.1 binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21 YP_002740807.1 catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_002740808.1 identified by match to protein family HMM PF00903 YP_002740809.1 catalyzes the formation of oxalozcetate and L-glutamate from L-aspartate and 2-oxoglutarate YP_002740810.1 identified by match to protein family HMM PF03413 YP_002740811.1 identified by glimmer; putative YP_002740812.1 identified by match to protein family HMM PF02525; match to protein family HMM PF03358 YP_002740813.1 identified by match to protein family HMM PF01391; match to protein family HMM PF04650; match to protein family HMM PF07501; match to protein family HMM TIGR01167; match to protein family HMM TIGR01168 YP_002740814.1 identified by match to protein family HMM PF05043; match to protein family HMM PF08270; match to protein family HMM PF08279; match to protein family HMM PF08280 YP_002740815.1 identified by match to protein family HMM PF03883 YP_002740818.1 cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+) YP_002740819.1 YghU; B2989; one of eight putative glutathione transferases from E. coli YP_002740820.1 identified by match to protein family HMM PF00122; match to protein family HMM PF00689; match to protein family HMM PF00690; match to protein family HMM PF00702; match to protein family HMM TIGR01494 YP_002740821.1 identified by match to protein family HMM PF01545; match to protein family HMM TIGR01297 YP_002740822.1 identified by match to protein family HMM PF00005 YP_002740823.1 catalyzes the addition and repair of the 3'-terminal CCA sequence in tRNA; these proteins belong to the CCA-adding enzyme subfamily 2 which does not have phosphohydrolase activity YP_002740824.1 catalyzes the reduction of 2,3-dihydrodipicolinate to 2,3,4,5-tetrahydrodipicolinate in lysine and diaminopimelate biosynthesis YP_002740825.1 identified by match to protein family HMM PF02645; match to protein family HMM TIGR00762 YP_002740826.1 identified by match to protein family HMM PF06619 YP_002740827.1 catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate YP_002740828.1 identified by match to protein family HMM PF07949 YP_002740829.1 identified by match to protein family HMM PF02457; match to protein family HMM TIGR00159 YP_002740830.1 identified by match to protein family HMM PF00070; match to protein family HMM PF07992 YP_002740831.1 identified by match to protein family HMM PF02650; match to protein family HMM TIGR00647 YP_002740832.1 identified by match to protein family HMM PF01933; match to protein family HMM TIGR01826 YP_002740833.1 identified by match to protein family HMM PF03668 YP_002740834.1 identified by match to protein family HMM PF01042; match to protein family HMM TIGR00004 YP_002740835.1 binds guanine nucleotides; in Escherichia coli depletion results in defective cell division and filamentation; in Bacillus subtilis this gene is essential YP_002740836.1 binds and unfolds substrates as part of the ClpXP protease YP_002740838.1 identified by match to protein family HMM PF00186 YP_002740839.1 identified by match to protein family HMM PF00210 YP_002740840.1 identified by match to protein family HMM PF01183; match to protein family HMM PF01473 YP_002740841.1 Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate YP_002740842.1 identified by match to protein family HMM PF04271; match to protein family HMM TIGR01446 YP_002740843.1 catalyzes the formation of O-succinyl-L-homoserine from succinyl-CoA and L-homoserine in methionine biosynthesis YP_002740844.1 catalyzes a salvage reaction resulting in the formation of AMP which is metabolically less costly than a de novo synthesis YP_002740845.1 identified by match to protein family HMM PF08241; match to protein family HMM PF08242 YP_002740846.1 identified by match to protein family HMM PF00005; match to protein family HMM PF03459; match to protein family HMM PF08402 YP_002740847.1 identified by glimmer; putative YP_002740848.1 identified by match to protein family HMM PF00857 YP_002740849.1 CodY; DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase (By similarity). It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor YP_002740850.1 identified by match to protein family HMM PF00270; match to protein family HMM PF00271 YP_002740852.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by match to protein family HMM PF01609 YP_002740853.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002740854.1 identified by match to protein family HMM PF07690 YP_002740855.1 Involved in disulfide oxidoreductase activity and electron transport YP_002740856.1 identified by match to protein family HMM PF08245; match to protein family HMM PF08353 YP_002740857.1 identified by match to protein family HMM PF07685 YP_002740858.1 identified by match to protein family HMM PF00557; match to protein family HMM PF01321 YP_002740859.1 identified by match to protein family HMM PF00665 YP_002740860.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002740862.1 catalyzes the formation of 4-amino-2-methyl-5-diphosphomethylpyrimidine YP_002740863.1 mediates pseudouridylation (positions 38, 39, 40) at the tRNA anticodon region which contributes to the structural stability YP_002740864.1 identified by match to protein family HMM PF07690 YP_002740865.1 identified by glimmer; putative YP_002740867.1 identified by match to protein family HMM PF03831; match to protein family HMM PF08274; match to protein family HMM TIGR00686 YP_002740868.1 Catalyzes the formation of (d)CDP from ATP and (d)CMP YP_002740871.1 identified by match to protein family HMM PF00535 YP_002740872.1 identified by match to protein family HMM PF00106; match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF04321; match to protein family HMM PF07993; match to protein family HMM TIGR01179 YP_002740874.1 identified by match to protein family HMM PF01266 YP_002740875.1 identified by match to protein family HMM PF01784; match to protein family HMM TIGR00486 YP_002740876.1 identified by match to protein family HMM PF04816 YP_002740878.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by match to protein family HMM PF00665 YP_002740879.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002740882.1 catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase YP_002740883.1 identified by match to protein family HMM PF00834 YP_002740884.1 identified by match to protein family HMM PF02378; match to protein family HMM TIGR01427 YP_002740885.1 identified by match to protein family HMM PF02379; match to protein family HMM TIGR00829 YP_002740886.1 identified by match to protein family HMM PF00359; match to protein family HMM TIGR00848 YP_002740887.1 identified by match to protein family HMM PF00359 YP_002740888.1 identified by match to protein family HMM PF00874; match to protein family HMM PF05043; match to protein family HMM PF08279 YP_002740889.1 identified by match to protein family HMM PF00122; match to protein family HMM PF00702; match to protein family HMM TIGR01494 YP_002740890.1 identified by match to protein family HMM PF01553 YP_002740891.1 identified by match to protein family HMM PF03596; match to protein family HMM TIGR00779 YP_002740892.1 primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence YP_002740897.1 catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr) YP_002740898.1 identified by match to protein family HMM PF02518 YP_002740899.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00486 YP_002740902.1 identified by match to protein family HMM PF02082 YP_002740903.1 identified by match to protein family HMM PF00149 YP_002740904.1 identified by match to protein family HMM PF01047; match to protein family HMM PF01325; match to protein family HMM PF02742; match to protein family HMM PF04023 YP_002740907.1 identified by glimmer; putative YP_002740910.1 hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr); possible defense mechanism against a harmful effect of D-tyrosine YP_002740911.1 identified by match to protein family HMM PF01966; match to protein family HMM PF02824; match to protein family HMM PF04607; match to protein family HMM TIGR00691 YP_002740912.1 identified by match to protein family HMM PF00753 YP_002740913.1 identified by match to protein family HMM PF01431; match to protein family HMM PF05649 YP_002740914.1 identified by match to protein family HMM PF00005 YP_002740915.1 identified by match to protein family HMM PF00950 YP_002740916.1 identified by match to protein family HMM PF01297 YP_002740917.1 antioxidant activity; thioredoxin-dependent thiol peroxidase; forms homodimers in solution; shows substrate specificity to alkyl hydroperoxides; periplasmic protein YP_002740918.1 identified by match to protein family HMM PF02687 YP_002740919.1 identified by match to protein family HMM PF00005 YP_002740921.1 2,3-bisphosphoglycerate-dependent; catalyzes the interconversion of 2-phosphoglycerate to 3-phosphoglycerate YP_002740924.1 IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase family type 1 subfamily; some organisms carry two different copies of this enzyme YP_002740926.1 identified by match to protein family HMM PF05103 YP_002740927.1 identified by match to protein family HMM PF01479 YP_002740928.1 identified by match to protein family HMM PF02325 YP_002740929.1 identified by match to protein family HMM PF04472 YP_002740930.1 identified by match to protein family HMM TIGR00044 YP_002740931.1 GTPase; similar structure to tubulin; forms ring-shaped polymers at the site of cell division; other proteins such as FtsA, ZipA, and ZapA, interact with and regulate FtsZ function YP_002740932.1 identified by match to protein family HMM PF02491; match to protein family HMM TIGR01174 YP_002740933.1 identified by match to protein family HMM TIGR02206 YP_002740934.1 identified by match to protein family HMM PF00293 YP_002740935.1 identified by match to protein family HMM PF01225; match to protein family HMM PF02875; match to protein family HMM PF08245; match to protein family HMM TIGR01143 YP_002740936.1 D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli YP_002740937.1 involved in a recombinational process of DNA repair, independent of the recBC complex YP_002740938.1 identified by match to protein family HMM PF00905; match to protein family HMM PF03717 YP_002740939.1 identified by match to protein family HMM PF01380; match to protein family HMM PF01418 YP_002740940.1 identified by match to protein family HMM PF00480 YP_002740941.1 identified by match to protein family HMM PF00701 YP_002740942.1 identified by match to protein family HMM PF04854 YP_002740944.1 identified by match to protein family HMM PF04074; match to protein family HMM TIGR00022 YP_002740945.1 identified by match to protein family HMM PF00528 YP_002740946.1 identified by match to protein family HMM PF00528 YP_002740947.1 identified by match to protein family HMM PF01547 YP_002740948.1 identified by match to protein family HMM PF00367; match to protein family HMM PF02378; match to protein family HMM TIGR00826 YP_002740949.1 Converts N-acetylmannosamine-6-phosphate to N-acetylglucosamine-6-phosphate YP_002740950.1 identified by match to protein family HMM PF01118; match to protein family HMM PF01408; match to protein family HMM PF02894; match to protein family HMM PF03447 YP_002740951.1 identified by match to protein family HMM PF02012; match to protein family HMM PF02973 YP_002740952.1 identified by match to protein family HMM PF00528 YP_002740953.1 identified by match to protein family HMM PF00528 YP_002740954.1 identified by match to protein family HMM PF01547 YP_002740955.1 identified by match to protein family HMM PF04074; match to protein family HMM TIGR00022 YP_002740956.1 identified by match to protein family HMM PF02012; match to protein family HMM PF02973; match to protein family HMM TIGR01167 YP_002740958.1 identified by glimmer; putative YP_002740959.1 identified by match to protein family HMM PF05448 YP_002740960.1 identified by glimmer; putative YP_002740961.1 catalyzes branch migration in Holliday junction intermediates YP_002740962.1 converts L-alanine to D-alanine which is used in cell wall biosynthesis; binds one pyridoxal phosphate per monomer; forms a homodimer YP_002740963.1 Catalyzes the formation of holo-ACP, which mediates the essential transfer of acyl fatty acid intermediates during the biosynthesis of fatty acids and lipids YP_002740964.1 catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, phenylalanine sensitive YP_002740965.1 catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, tyrosine sensitive YP_002740966.1 functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond SecA1; SecA2 is not essential and seems to play a role in secretion of a subset of proteins YP_002740967.1 identified by match to protein family HMM PF00005 YP_002740972.1 EngA; essential Neisserial GTPase; synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains YP_002740973.1 Primosomal protein that may act to load helicase DnaC during DNA replication YP_002740974.1 identified by match to protein family HMM PF07261 YP_002740975.1 identified by match to protein family HMM PF03477; match to protein family HMM TIGR00244 YP_002740976.1 identified by match to protein family HMM PF00392 YP_002740977.1 identified by match to protein family HMM PF00005 YP_002740980.1 identified by match to protein family HMM PF00005 YP_002740982.1 identified by match to protein family HMM PF09335 YP_002740983.1 identified by match to protein family HMM PF00480 YP_002740984.1 identified by match to protein family HMM PF00358; match to protein family HMM PF00367; match to protein family HMM PF02378; match to protein family HMM TIGR00826; match to protein family HMM TIGR00830; match to protein family HMM TIGR01996 YP_002740986.1 identified by match to protein family HMM PF00251; match to protein family HMM PF08244; match to protein family HMM TIGR01322 YP_002740987.1 identified by match to protein family HMM PF00356; match to protein family HMM PF00532 YP_002740988.1 identified by match to protein family HMM TIGR00532 YP_002740989.1 identified by match to protein family HMM PF01154; match to protein family HMM PF08540; match to protein family HMM TIGR01835 YP_002740991.1 identified by match to protein family HMM PF01609 YP_002740992.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002740994.1 identified by match to protein family HMM PF06738 YP_002740995.1 identified by match to protein family HMM PF00069; match to protein family HMM PF01163; match to protein family HMM PF03793 YP_002740996.1 identified by match to protein family HMM PF00481 YP_002740997.1 identified by match to protein family HMM PF01029; match to protein family HMM PF01189; match to protein family HMM TIGR00563 YP_002740998.1 modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet) which is important in translation initiation; inactivation of this gene in Escherichia coli severely impairs growth YP_002740999.1 binding of PriA to forked DNA starts the assembly of the primosome, also possesses 3'-5' helicase activity YP_002741000.1 Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits YP_002741001.1 Essential for recycling GMP and indirectly, cGMP YP_002741002.1 identified by match to protein family HMM PF00013; match to protein family HMM PF01966; match to protein family HMM TIGR00277; match to protein family HMM TIGR03319 YP_002741003.1 identified by match to protein family HMM PF02604; match to protein family HMM TIGR01552 YP_002741004.1 identified by match to protein family HMM PF05636 YP_002741005.1 identified by match to protein family HMM PF08241; match to protein family HMM PF08242 YP_002741006.1 identified by match to protein family HMM PF02410; match to protein family HMM TIGR00090 YP_002741007.1 identified by match to protein family HMM PF00857 YP_002741008.1 identified by match to protein family HMM PF01966; match to protein family HMM TIGR00488 YP_002741009.1 transfers an adenyl group from ATP to NaMN to form nicotinic acid adenine dinucleotide (NaAD) which is then converted to the ubiquitous compound NAD by NAD synthetase; essential enzyme in bacteria YP_002741010.1 identified by match to protein family HMM PF01985; match to protein family HMM TIGR00253 YP_002741011.1 in Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis YP_002741012.1 identified by match to protein family HMM TIGR01662; match to protein family HMM TIGR01668 YP_002741013.1 identified by match to protein family HMM PF01544 YP_002741014.1 identified by match to protein family HMM PF00924 YP_002741015.1 involved in the import of serine and threonine coupled with the import of sodium YP_002741016.1 identified by match to protein family HMM PF06081 YP_002741020.1 identified by match to protein family HMM TIGR02919 YP_002741021.1 identified by match to protein family HMM PF00534; match to protein family HMM PF09318; match to protein family HMM TIGR02918 YP_002741025.1 forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase YP_002741026.1 identified by match to protein family HMM PF00535 YP_002741027.1 identified by match to protein family HMM PF01501 YP_002741028.1 identified by match to protein family HMM PF01501 YP_002741029.1 identified by match to protein family HMM PF01501; match to protein family HMM PF08759 YP_002741031.1 identified by match to protein family HMM PF00132 YP_002741032.1 identified by match to protein family HMM PF01501 YP_002741033.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by match to protein family HMM PF01609 YP_002741034.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002741036.1 identified by match to protein family HMM PF00746; match to protein family HMM TIGR01167 YP_002741037.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002741038.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002741039.1 identified by match to protein family HMM PF01047 YP_002741041.1 identified by match to protein family HMM PF00085; match to protein family HMM TIGR01068 YP_002741042.1 NADPH-dependent; catalyzes the reduction of 7-cyano-7-deazaguanine to 7-aminomethyl-7-deazaguanine in queuosine biosynthesis YP_002741043.1 identified by match to protein family HMM PF00230 YP_002741045.1 identified by glimmer; putative YP_002741046.1 identified by match to protein family HMM PF01432; match to protein family HMM PF08439; match to protein family HMM TIGR00181 YP_002741047.1 in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA; cells lacking this function can grow, but are outcompeted by wild-type; SAM-dependent m(3)U1498 methyltransferase YP_002741048.1 methylates ribosomal protein L11 at multiple amino acid positions; mutations of these genes in Escherichia coli or Thermus thermophilus has no apparent phenotype YP_002741049.1 identified by match to protein family HMM PF00293 YP_002741050.1 identified by match to protein family HMM PF02163 YP_002741052.1 identified by match to protein family HMM PF03681 YP_002741053.1 identified by match to protein family HMM PF07927 YP_002741056.1 identified by match to protein family HMM PF00004 YP_002741057.1 identified by match to protein family HMM PF00589 YP_002741060.1 identified by glimmer; putative YP_002741061.1 identified by glimmer; putative YP_002741062.1 identified by glimmer; putative YP_002741063.1 identified by glimmer; putative YP_002741065.1 identified by match to protein family HMM PF00251; match to protein family HMM TIGR01322 YP_002741066.1 identified by match to protein family HMM PF00528 YP_002741067.1 identified by match to protein family HMM PF00528 YP_002741068.1 identified by match to protein family HMM PF01547 YP_002741069.1 identified by match to protein family HMM PF00356; match to protein family HMM PF00532 YP_002741070.1 identified by match to protein family HMM PF05043; match to protein family HMM PF08270; match to protein family HMM PF08279; match to protein family HMM PF08280 YP_002741071.1 identified by match to protein family HMM PF04226 YP_002741074.1 identified by match to protein family HMM PF03780 YP_002741075.1 identified by match to protein family HMM PF05532 YP_002741077.1 identified by glimmer; putative YP_002741078.1 identified by match to protein family HMM PF01925 YP_002741079.1 identified by match to protein family HMM PF03781 YP_002741080.1 can hydrolyze p-nitrophenyl sulfate; contains a specific cysteine that is converted into C{alpha]-formylglycine upon activation with the anaerobic sulfatase-maturase YP_002741081.1 identified by match to protein family HMM PF02378; match to protein family HMM TIGR00410 YP_002741082.1 identified by match to protein family HMM PF02255 YP_002741083.1 identified by match to protein family HMM PF02302 YP_002741085.1 identified by match to protein family HMM PF02378; match to protein family HMM TIGR00410 YP_002741086.1 identified by match to protein family HMM PF00480 YP_002741087.1 identified by match to protein family HMM PF00583 YP_002741088.1 identified by match to protein family HMM PF01478; match to protein family HMM PF06750 YP_002741089.1 identified by match to protein family HMM PF01381; match to protein family HMM PF06114 YP_002741091.1 catalyzes the formation of indole and glyceraldehyde 3-phosphate from indoleglycerol phosphate in tryptophan biosynthesis YP_002741092.1 catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate YP_002741093.1 catalyzes the formation of 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate from N-(5-phospho-beta-D-ribosyl)-anthranilate in tryptophan biosynthesis YP_002741094.1 involved in tryptophan biosynthesis; amino acid biosynthesis; converts 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate to C(1)-(3-indolyl)-glycerol 3-phosphate and carbon dioxide and water YP_002741095.1 Catalyzes the conversion of N-(5-phospho-D-ribosyl)-anthranilate and diphosphate to anthranilate and 5-phospho-alpha-D-ribose 1-diphosphate YP_002741096.1 TrpG; with TrpE catalyzes the formation of anthranilate and glutamate from chorismate and glutamine; TrpG provides the glutamine amidotransferase activity YP_002741097.1 with component II, the glutamine amidotransferase, catalyzes the formation of anthranilate from chorismate and glutamine YP_002741101.1 identified by match to protein family HMM PF00356; match to protein family HMM PF00532 YP_002741102.1 identified by match to protein family HMM PF02308 YP_002741103.1 identified by match to protein family HMM PF00528 YP_002741104.1 identified by match to protein family HMM PF00005; match to protein family HMM PF03459; match to protein family HMM PF08402 YP_002741106.1 identified by match to protein family HMM PF08975 YP_002741109.1 identified by match to protein family HMM PF04650; match to protein family HMM TIGR01168 YP_002741110.1 identified by match to protein family HMM PF01041 YP_002741111.1 identified by match to protein family HMM PF02397 YP_002741112.1 identified by match to protein family HMM PF00005; match to protein family HMM PF00664 YP_002741113.1 identified by match to protein family HMM PF00005; match to protein family HMM PF00664 YP_002741114.1 identified by match to protein family HMM PF04239 YP_002741115.1 identified by glimmer; putative YP_002741116.1 identified by glimmer; putative YP_002741117.1 identified by match to protein family HMM PF03372; match to protein family HMM TIGR00195; match to protein family HMM TIGR00633 YP_002741118.1 Catalyzes the transfer of the phosphoribosyl moiety from 5-phospho--D-ribosyl-1-pyrophosphate (PRib-PP) to the 6-oxo-guanine and -xanthine YP_002741119.1 identified by match to protein family HMM PF00860; match to protein family HMM PF00916; match to protein family HMM TIGR00801; match to protein family HMM TIGR03173 YP_002741120.1 identified by match to protein family HMM PF04556 YP_002741121.1 identified by match to protein family HMM PF01555 YP_002741122.1 identified by match to protein family HMM PF02086; match to protein family HMM TIGR00571 YP_002741123.1 identified by match to protein family HMM PF03061; match to protein family HMM TIGR00369 YP_002741124.1 catalyzes the formation of alpha-D-glucose 1-phosphate and UDP-galactose from UDP-glucose and alpha-D-galactose 1-phosphate in galactose metabolism YP_002741125.1 catalyzes the formation of alpha-D-galactose 1-phosphate from D-galactose in galactose metabolism YP_002741126.1 identified by match to protein family HMM PF00356; match to protein family HMM PF00532 YP_002741127.1 identified by match to protein family HMM PF00107; match to protein family HMM PF08240 YP_002741128.1 identified by match to protein family HMM PF00376 YP_002741129.1 identified by match to protein family HMM PF01545; match to protein family HMM TIGR01297 YP_002741130.1 identified by match to protein family HMM PF00440 YP_002741131.1 identified by match to protein family HMM PF04973; match to protein family HMM TIGR01528 YP_002741132.1 identified by glimmer; putative YP_002741133.1 identified by match to protein family HMM PF00528; match to protein family HMM PF04069 YP_002741134.1 identified by match to protein family HMM PF00005 YP_002741135.1 identified by match to protein family HMM PF07366 YP_002741136.1 identified by match to protein family HMM PF01047 YP_002741138.1 identified by match to protein family HMM PF05343; match to protein family HMM TIGR03107 YP_002741140.1 identified by match to protein family HMM PF00106; match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF07993 YP_002741141.1 identified by match to protein family HMM PF01032 YP_002741142.1 identified by match to protein family HMM PF01032 YP_002741143.1 identified by match to protein family HMM PF00005 YP_002741144.1 identified by match to protein family HMM PF01497 YP_002741145.1 identified by match to protein family HMM PF01809; match to protein family HMM TIGR00278 YP_002741146.1 identified by match to protein family HMM PF00849; match to protein family HMM PF01479; match to protein family HMM TIGR00093 YP_002741147.1 functions during chromosome segregation; may form a condensin-like structure with SMC and ScpA; forms a homodimer YP_002741148.1 functions during chromosome segregation; may form a condensin-like structure with SMC and ScpB YP_002741149.1 site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs YP_002741150.1 identified by match to protein family HMM PF00571 YP_002741151.1 identified by match to protein family HMM PF00149; match to protein family HMM TIGR00040 YP_002741152.1 HAM1-like protein; Rec-dependent growth; RgdB; yggV; it is suspected that this protein functions to remove misincorporated bases such as xanthine or hypoxanthine YP_002741153.1 converts L-glutamate to D-glutamate, a component of peptidoglycan YP_002741154.1 identified by match to protein family HMM PF03672 YP_002741155.1 identified by match to protein family HMM PF00128; match to protein family HMM TIGR02403 YP_002741156.1 identified by match to protein family HMM PF00358; match to protein family HMM PF00367; match to protein family HMM PF02378; match to protein family HMM TIGR00826; match to protein family HMM TIGR00830; match to protein family HMM TIGR01992 YP_002741157.1 identified by match to protein family HMM PF00392; match to protein family HMM PF07702; match to protein family HMM TIGR02404 YP_002741158.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002741159.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by match to protein family HMM PF01610 YP_002741160.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by match to protein family HMM PF01610 YP_002741161.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002741162.1 identified by match to protein family HMM PF00005; match to protein family HMM PF08352 YP_002741163.1 identified by match to protein family HMM PF00005; match to protein family HMM PF08352; match to protein family HMM TIGR01727 YP_002741164.1 identified by match to protein family HMM PF00528 YP_002741165.1 identified by match to protein family HMM PF00528 YP_002741166.1 identified by match to protein family HMM PF00496 YP_002741167.1 identified by match to protein family HMM PF04932 YP_002741168.1 identified by match to protein family HMM PF00128 YP_002741170.1 identified by match to protein family HMM PF00528 YP_002741171.1 identified by match to protein family HMM PF00528 YP_002741172.1 identified by match to protein family HMM PF01547 YP_002741173.1 identified by match to protein family HMM PF02065 YP_002741174.1 identified by match to protein family HMM PF00165; match to protein family HMM PF02311 YP_002741175.1 catalyzes the formation of biotinyl-5'-AMP, also acts as a transcriptional repressor of the biotin operon YP_002741177.1 identified by match to protein family HMM PF01938; match to protein family HMM PF05958; match to protein family HMM TIGR00479 YP_002741178.1 binds RecA and inhibits RecA-mediated DNA strand exchange and ATP hydrolysis and coprotease activities YP_002741179.1 identified by match to protein family HMM PF04167 YP_002741182.1 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth YP_002741183.1 10 kDa chaperonin; Cpn10; GroES; forms homoheptameric ring; binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it; folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES; release of the folded substrate is dependent on ATP binding and hydrolysis in the trans ring YP_002741184.1 binds to single stranded DNA and may facilitate the binding and interaction of other proteins to DNA YP_002741185.1 identified by match to protein family HMM PF00106; match to protein family HMM PF08659 YP_002741186.1 identified by match to protein family HMM PF01588 YP_002741187.1 identified by match to protein family HMM PF00085 YP_002741189.1 identified by match to protein family HMM PF01473 YP_002741191.1 identified by match to protein family HMM PF04397 YP_002741192.1 identified by match to protein family HMM PF01569 YP_002741194.1 identified by match to protein family HMM PF00005 YP_002741195.1 identified by match to protein family HMM PF00664 YP_002741196.1 identified by match to protein family HMM PF01047 YP_002741197.1 identified by match to protein family HMM PF01709; match to protein family HMM TIGR01033 YP_002741198.1 identified by match to protein family HMM PF01289 YP_002741201.1 identified by glimmer; putative YP_002741211.1 identified by match to protein family HMM PF01473; match to protein family HMM PF01510 YP_002741213.1 identified by match to protein family HMM PF01554; match to protein family HMM TIGR00797 YP_002741214.1 catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs YP_002741215.1 identified by match to protein family HMM PF00994; match to protein family HMM PF02464; match to protein family HMM TIGR00199; match to protein family HMM TIGR00200 YP_002741216.1 identified by match to protein family HMM PF03816; match to protein family HMM TIGR00350 YP_002741217.1 identified by match to protein family HMM PF00583 YP_002741218.1 identified by match to protein family HMM PF02367; match to protein family HMM TIGR00150 YP_002741220.1 identified by match to protein family HMM PF01381 YP_002741222.1 identified by match to protein family HMM PF07242; match to protein family HMM TIGR01654 YP_002741223.1 identified by match to protein family HMM PF00005 YP_002741225.1 catalyzes the formation of nucleoside triphosphate from ATP and nucleoside diphosphate YP_002741226.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Subunit beta' binds to sigma factor allowing it to bind to the -10 region of the promoter YP_002741227.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme YP_002741228.1 identified by glimmer; putative YP_002741229.1 identified by match to protein family HMM PF00571; match to protein family HMM PF01595; match to protein family HMM PF03471 YP_002741230.1 identified by match to protein family HMM PF01223 YP_002741232.1 adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active YP_002741235.1 Catalyzes the conversion of ATP and pantetheine 4'-phosphate to diphosphate and 3'-dephospho-coA YP_002741236.1 identified by match to protein family HMM PF03602 YP_002741237.1 catalyzes the formation of asparagine from aspartate and ammonia YP_002741238.1 identified by match to protein family HMM PF01027 YP_002741239.1 identified by match to protein family HMM PF00588; match to protein family HMM PF08032 YP_002741240.1 catalyzes the hydrolysis of acylphosphate YP_002741241.1 involved in biogenesis of membrane proteins; Firmicutes specific proteins are shorter than other bacterial counterparts and have a signal peptide and lipid attachment site YP_002741242.1 identified by match to protein family HMM PF04055; match to protein family HMM TIGR02493 YP_002741243.1 identified by match to protein family HMM PF00278; match to protein family HMM PF02784 YP_002741244.1 identified by match to protein family HMM PF00156; match to protein family HMM PF09182; match to protein family HMM TIGR01743 YP_002741245.1 identified by match to protein family HMM PF01336; match to protein family HMM PF01966 YP_002741246.1 identified by match to protein family HMM PF02646 YP_002741247.1 identified by match to protein family HMM PF04263; match to protein family HMM PF04265; match to protein family HMM TIGR01378 YP_002741248.1 identified by match to protein family HMM PF00834; match to protein family HMM TIGR01163 YP_002741249.1 EngC; RsgA; CpgA; circularly permuted GTPase; ribosome small subunit-dependent GTPase A; has the pattern G4-G1-G3 as opposed to other GTPases; interacts strongly with 30S ribosome which stimulates GTPase activity YP_002741250.1 catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin YP_002741252.1 identified by match to protein family HMM PF00005 YP_002741253.1 identified by match to protein family HMM PF07242; match to protein family HMM TIGR01654 YP_002741254.1 identified by match to protein family HMM TIGR01653 YP_002741256.1 identified by match to protein family HMM PF01751; match to protein family HMM TIGR00334 YP_002741257.1 identified by match to protein family HMM PF01026; match to protein family HMM TIGR00010 YP_002741258.1 identified by match to protein family HMM PF00746; match to protein family HMM TIGR01167 YP_002741259.1 in Escherichia coli transcription of this gene is enhanced by polyamines YP_002741260.1 broad specificity; family IV; in Corynebacterium glutamicum this protein can use glutamate, 2-aminobutyrate, and aspartate as amino donors and pyruvate as the acceptor YP_002741261.1 identified by glimmer; putative YP_002741262.1 identified by match to protein family HMM PF00582 YP_002741263.1 identified by match to protein family HMM PF00702; match to protein family HMM PF05116; match to protein family HMM PF08282; match to protein family HMM TIGR00099; match to protein family HMM TIGR01484 YP_002741264.1 identified by match to protein family HMM PF00710 YP_002741265.1 identified by glimmer; putative YP_002741266.1 identified by match to protein family HMM PF00356; match to protein family HMM PF00532; match to protein family HMM TIGR01481 YP_002741267.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00196 YP_002741268.1 identified by match to protein family HMM PF02518; match to protein family HMM PF07730 YP_002741269.1 identified by match to protein family HMM PF01061 YP_002741270.1 identified by match to protein family HMM PF00005 YP_002741274.1 Modulates Rho-dependent transcription termination YP_002741275.1 forms a complex with SecY and SecG; SecYEG forms a putative protein-conducting channel to which secA binds and translocates targeted polypeptides across the cytoplasmic membrane, a process driven by ATP and a proton-motive force YP_002741276.1 in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group have the CXXC motif YP_002741277.1 identified by match to protein family HMM PF00905; match to protein family HMM PF00912; match to protein family HMM TIGR02074 YP_002741278.1 identified by match to protein family HMM PF00849 YP_002741279.1 identified by match to protein family HMM PF00044; match to protein family HMM PF02800; match to protein family HMM TIGR01534 YP_002741280.1 identified by match to protein family HMM PF02687 YP_002741282.1 identified by match to protein family HMM PF01710 YP_002741283.1 catalyzes the formation of pyridine-2,3-dicarboxylate and 5-phospho-alpha-D-ribose 1-diphosphate from nictinate D-ribonucleotide YP_002741284.1 identified by match to protein family HMM PF03600; match to protein family HMM PF07158 YP_002741286.1 identified by match to protein family HMM PF00392; match to protein family HMM PF07702 YP_002741287.1 identified by match to protein family HMM PF00232 YP_002741288.1 identified by match to protein family HMM PF02378; match to protein family HMM TIGR00410 YP_002741289.1 identified by match to protein family HMM PF02302 YP_002741290.1 identified by match to protein family HMM PF02255 YP_002741291.1 identified by match to protein family HMM PF00465 YP_002741293.1 identified by match to protein family HMM PF02493 YP_002741294.1 identified by match to protein family HMM PF01451 YP_002741295.1 member of preprotein translocase; forms a heterotrimer with SecD and SecF; links the SecD/SecF/YajC/YidC complex with the SecY/SecE/SecG complex YP_002741296.1 catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase YP_002741298.1 identified by match to protein family HMM PF00874; match to protein family HMM PF08279 YP_002741299.1 catalyzes the formation of D-xylulose 5-phosphate from L-ribulose 5-phosphate in the L-arabinose and L-ascorbate degradation pathways YP_002741300.1 L-xylulose 5-phosphate 3-epimerase activity not yet demonstrated; may be involved in the utilization of 2,3-diketo-L-gulonate YP_002741301.1 catalyzes the formation of L-xylulose-5-phosphate from 3-keto-L-gulonate-6-phosphate in anaerobic L-ascorbate utilization YP_002741302.1 identified by match to protein family HMM PF00359 YP_002741303.1 identified by match to protein family HMM PF02302 YP_002741304.1 membrane component; functions with enzymes IIB (sgaB; ulaB) and IIA (sgaA; ulaC) enzyme I and HPr for anaerobic utilization and uptake of L-ascorbate; sgaTBA are regulated by yifQ as well as Crp and Fnr YP_002741306.1 identified by match to protein family HMM PF01424 YP_002741307.1 identified by match to protein family HMM PF02096 YP_002741308.1 protein component of RNaseP which catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'terminus; this enzyme also cleaves other RNA substrates YP_002741310.1 AckA utilizes acetate and can acetylate CheY which increases signal strength during flagellar rotation; utilizes magnesium and ATP; also involved in conversion of acetate to aceyl-CoA YP_002741312.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002741313.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002741314.1 identified by match to protein family HMM PF00583 YP_002741319.1 identified by match to protein family HMM PF07963; match to protein family HMM TIGR02532 YP_002741320.1 identified by match to protein family HMM PF00482 YP_002741321.1 identified by match to protein family HMM PF00437 YP_002741322.1 identified by match to protein family HMM PF06279 YP_002741323.1 identified by match to protein family HMM PF00107; match to protein family HMM PF08240 YP_002741324.1 identified by match to protein family HMM PF01979; match to protein family HMM TIGR00221 YP_002741325.1 identified by match to protein family HMM PF01757 YP_002741326.1 identified by glimmer; putative YP_002741327.1 Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr) YP_002741328.1 identified by match to protein family HMM PF06161 YP_002741329.1 identified by match to protein family HMM PF06993 YP_002741330.1 identified by match to protein family HMM PF01022; match to protein family HMM PF01047 YP_002741331.1 identified by match to protein family HMM PF01476 YP_002741332.1 identified by match to protein family HMM PF01554; match to protein family HMM PF03023; match to protein family HMM TIGR00797 YP_002741333.1 catalyzes the formation of L-threonine from O-phospho-L-homoserine YP_002741336.1 Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation YP_002741337.1 functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis; catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate; member of PGI family YP_002741339.1 identified by match to protein family HMM PF00117; match to protein family HMM PF07722 YP_002741340.1 identified by match to protein family HMM PF00005; match to protein family HMM PF00664 YP_002741342.1 identified by match to protein family HMM PF00005; match to protein family HMM PF00664 YP_002741343.1 This protein performs the mismatch recognition step during the DNA repair process YP_002741344.1 identified by match to protein family HMM PF01316; match to protein family HMM PF02863; match to protein family HMM TIGR01529 YP_002741345.1 catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase YP_002741346.1 identified by match to protein family HMM PF01609 YP_002741347.1 identified by match to protein family HMM PF06172 YP_002741348.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00486 YP_002741349.1 identified by match to protein family HMM PF00512; match to protein family HMM PF02518 YP_002741351.1 identified by match to protein family HMM PF00528; match to protein family HMM TIGR02138 YP_002741352.1 identified by match to protein family HMM PF00528; match to protein family HMM TIGR00974 YP_002741353.1 ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation YP_002741354.1 identified by match to protein family HMM PF01895; match to protein family HMM TIGR02135 YP_002741356.1 catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate YP_002741357.1 identified by match to protein family HMM PF00483; match to protein family HMM TIGR01099 YP_002741358.1 identified by glimmer; putative YP_002741359.1 identified by match to protein family HMM PF01694 YP_002741360.1 identified by match to protein family HMM PF01812; match to protein family HMM TIGR02727 YP_002741361.1 identified by match to protein family HMM PF01546; match to protein family HMM PF07687; match to protein family HMM TIGR01891 YP_002741362.1 identified by match to protein family HMM PF00132; match to protein family HMM PF08503 YP_002741363.1 identified by match to protein family HMM PF00892 YP_002741364.1 identified by match to protein family HMM PF00905; match to protein family HMM PF00912 YP_002741365.1 catalyzes the formation of tyrosyl-tRNA(Tyr) from tyrosine and tRNA(Tyr) YP_002741366.1 identified by match to protein family HMM PF00122; match to protein family HMM PF00702; match to protein family HMM TIGR01494; match to protein family HMM TIGR01525 YP_002741368.1 identified by match to protein family HMM PF08241 YP_002741370.1 identified by match to protein family HMM PF00343; match to protein family HMM TIGR02093 YP_002741371.1 amylomaltase; acts to release glucose from maltodextrins YP_002741372.1 identified by match to protein family HMM PF01547 YP_002741373.1 identified by match to protein family HMM PF00528; match to protein family HMM PF05154 YP_002741374.1 identified by match to protein family HMM PF00528 YP_002741376.1 identified by match to protein family HMM PF00356; match to protein family HMM PF00532 YP_002741377.1 identified by glimmer; putative YP_002741378.1 identified by match to protein family HMM PF02588 YP_002741379.1 catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes YP_002741382.1 identified by match to protein family HMM PF02517 YP_002741385.1 identified by match to protein family HMM PF01381 YP_002741387.1 identified by glimmer; putative YP_002741389.1 catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG YP_002741390.1 identified by match to protein family HMM PF00933 YP_002741391.1 identified by match to protein family HMM PF00933 YP_002741393.1 Converts D-mannonate to D-mannuronate YP_002741394.1 catalyzes the formation of 2-dehydro-3-deoxy-D-gluconate from mannonate YP_002741395.1 catalyzes the interconversion of D-glucuronate to D-fructuronate or D-galacturonate to D-tagaturonate; functions in glucuronic and galacturonic metabolism YP_002741396.1 identified by match to protein family HMM PF01081; match to protein family HMM TIGR01182 YP_002741397.1 identified by match to protein family HMM PF00392; match to protein family HMM PF07729 YP_002741398.1 identified by match to protein family HMM PF00703; match to protein family HMM PF02836; match to protein family HMM PF02837 YP_002741399.1 identified by match to protein family HMM PF00294 YP_002741401.1 identified by glimmer; putative YP_002741402.1 identified by glimmer; putative YP_002741405.1 identified by match to protein family HMM TIGR01716 YP_002741407.1 identified by match to protein family HMM PF01883 YP_002741409.1 catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis YP_002741410.1 identified by match to protein family HMM PF02779; match to protein family HMM PF02780 YP_002741411.1 identified by match to protein family HMM PF00456 YP_002741412.1 membrane component; functions with enzymes IIB (sgaB; ulaB) and IIA (sgaA; ulaC) enzyme I and HPr for anaerobic utilization and uptake of L-ascorbate; sgaTBA are regulated by yifQ as well as Crp and Fnr YP_002741413.1 identified by match to protein family HMM PF02302 YP_002741414.1 identified by match to protein family HMM PF00359; match to protein family HMM PF00874 YP_002741415.1 identified by match to protein family HMM PF01145 YP_002741417.1 some L32 proteins have zinc finger motifs consisting of CXXC while others do not YP_002741418.1 in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif YP_002741419.1 identified by match to protein family HMM PF01473 YP_002741420.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by glimmer; putative YP_002741421.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002741422.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002741423.1 identified by glimmer; putative YP_002741424.1 identified by glimmer; putative YP_002741425.1 identified by match to protein family HMM PF00728 YP_002741426.1 identified by match to protein family HMM PF00480 YP_002741427.1 identified by match to protein family HMM PF01074; match to protein family HMM PF07748 YP_002741428.1 identified by match to protein family HMM PF06824 YP_002741429.1 identified by match to protein family HMM PF07971; match to protein family HMM TIGR01180 YP_002741430.1 identified by match to protein family HMM PF00754 YP_002741431.1 catalyzes the degradation of arginine to citruline and ammonia YP_002741432.1 catalyzes the formation of ornithine and carbamylphosphate from citrulline in the arginine catabolic pathway YP_002741433.1 catalyzes the reversible synthesis of carbamate and ATP from carbamoyl phosphate and ADP YP_002741434.1 identified by match to protein family HMM PF03606 YP_002741435.1 identified by match to protein family HMM PF01546; match to protein family HMM TIGR01887 YP_002741436.1 identified by match to protein family HMM PF04650; match to protein family HMM TIGR01168 YP_002741437.1 identified by glimmer; putative YP_002741438.1 identified by match to protein family HMM PF01145 YP_002741439.1 identified by match to protein family HMM PF00465 YP_002741440.1 catalyzes the conversion of the aldose L-fucose into the corresponding ketose L-fuculose YP_002741441.1 identified by match to protein family HMM PF00596 YP_002741442.1 identified by match to protein family HMM PF08305 YP_002741443.1 identified by match to protein family HMM PF02065 YP_002741445.1 identified by match to protein family HMM PF01120 YP_002741446.1 identified by match to protein family HMM PF00528 YP_002741447.1 identified by match to protein family HMM PF00528 YP_002741448.1 identified by match to protein family HMM PF01547 YP_002741449.1 identified by match to protein family HMM PF00370 YP_002741450.1 identified by match to protein family HMM PF00455; match to protein family HMM PF08220; match to protein family HMM PF08279 YP_002741451.1 identified by match to protein family HMM PF01297; match to protein family HMM PF09223 YP_002741452.1 identified by match to protein family HMM PF00950 YP_002741453.1 identified by match to protein family HMM PF00005 YP_002741454.1 identified by match to protein family HMM PF01022; match to protein family HMM PF01047; match to protein family HMM PF01325; match to protein family HMM PF01978; match to protein family HMM PF08279 YP_002741456.1 identified by match to protein family HMM PF04914; match to protein family HMM PF04915; match to protein family HMM PF04918 YP_002741457.1 D-alanyl carrier protein subunit; involved in the incorporation of D-alanine into membrane-associated D-alanyl-lipoteichoic acid; D-alanyl carrier protein is the acceptor of activated D-alanine which it donates to a membrane acceptor(D-alanyl transferase) for incorporation into membrane lipoteichoic acid YP_002741458.1 transfers D-alanine to the D-alanyl carrier protein during the incorporation of D-alanine into lipoteichoic acid YP_002741461.1 identified by match to protein family HMM PF00078; match to protein family HMM PF08388 YP_002741463.1 identified by glimmer; putative YP_002741464.1 identified by match to protein family HMM PF00230; match to protein family HMM TIGR00861 YP_002741465.1 identified by match to protein family HMM PF01266 YP_002741466.1 Converts glycerol and ADP to glycerol-3-phosphate and ADP YP_002741467.1 identified by match to protein family HMM PF05043 YP_002741468.1 becomes active under oxidative stress; four conserved cysteines bind a zinc atom when they are in the reduced state and the enzyme is inactive; oxidative stress results in oxidized cysteines, release of zinc, and binding of Hsp33 to aggregation-prone proteins; forms dimers and higher order oligomers YP_002741469.1 identified by match to protein family HMM PF00724; match to protein family HMM PF01180; match to protein family HMM PF01207; match to protein family HMM TIGR00737 YP_002741470.1 identified by match to protein family HMM PF01473; match to protein family HMM PF04650; match to protein family HMM PF05062; match to protein family HMM TIGR01168 YP_002741471.1 identified by match to protein family HMM PF04140 YP_002741472.1 identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518 YP_002741473.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00486 YP_002741476.1 identified by match to protein family HMM PF00004; match to protein family HMM PF02861; match to protein family HMM PF07724; match to protein family HMM PF07728 YP_002741477.1 identified by match to protein family HMM PF05848 YP_002741478.1 identified by match to protein family HMM PF00005 YP_002741479.1 identified by match to protein family HMM PF09084 YP_002741480.1 identified by match to protein family HMM PF00528 YP_002741482.1 identified by match to protein family HMM PF01473; match to protein family HMM PF05257; match to protein family HMM PF08460 YP_002741483.1 identified by match to protein family HMM PF06257 YP_002741484.1 unwinds double stranded DNA YP_002741485.1 in Escherichia coli this protein is wrapped around the base of the L1 stalk YP_002741486.1 identified by match to protein family HMM PF01368; match to protein family HMM PF02272 YP_002741487.1 identified by match to protein family HMM PF02482; match to protein family HMM TIGR00741 YP_002741489.1 identified by match to protein family HMM PF00271; match to protein family HMM PF04851 YP_002741490.1 identified by match to protein family HMM PF01205; match to protein family HMM PF09186; match to protein family HMM TIGR00257 YP_002741491.1 identified by match to protein family HMM PF00291; match to protein family HMM TIGR01136; match to protein family HMM TIGR01139 YP_002741492.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by match to protein family HMM PF03050 YP_002741494.1 identified by match to protein family HMM PF05717 YP_002741495.1 EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu YP_002741496.1 one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit YP_002741497.1 identified by match to protein family HMM PF05257 YP_002741498.1 identified by match to protein family HMM PF04093; match to protein family HMM TIGR03426 YP_002741499.1 in some organisms this protein is a transmembrane protein while in others it is periplasmic; involved in some organisms with other components of the MreBCD complex and with penicillin binding proteins in the periplasm or cell wall YP_002741500.1 identified by match to protein family HMM PF02361 YP_002741501.1 with CbiNQ forms the ABC transporter for cobalt import; Streptococcus has two adjacent copies of this gene YP_002741502.1 with CbiNQ forms the ABC transporter for cobalt import; Streptococcus has two adjacent copies of this gene YP_002741503.1 identified by match to protein family HMM PF01066; match to protein family HMM TIGR00560 YP_002741505.1 identified by match to protein family HMM PF00675; match to protein family HMM PF05193 YP_002741506.1 identified by match to protein family HMM PF05193 YP_002741507.1 identified by match to protein family HMM TIGR02988 YP_002741508.1 Required for DNA replication; binds preferentially to single-stranded, linear DNA YP_002741509.1 catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate YP_002741510.1 catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_002741511.1 identified by match to protein family HMM PF00005 YP_002741513.1 identified by glimmer; putative YP_002741514.1 identified by glimmer; putative YP_002741515.1 identified by match to protein family HMM PF00440 YP_002741516.1 identified by match to protein family HMM PF00072; match to protein family HMM PF04397 YP_002741517.1 identified by match to protein family HMM PF02518 YP_002741518.1 identified by match to protein family HMM PF03047 YP_002741519.1 SPOUT methyltransferase family protein; crystal structure shows homodimer; in Escherichia coli this protein methylates pseudouridine at position 1915 of the 23S ribosomal RNA YP_002741520.1 identified by match to protein family HMM PF00089 YP_002741521.1 identified by match to protein family HMM PF02195; match to protein family HMM TIGR00180