-- dump date 20140620_084413 -- class Genbank::Feature -- table feature -- table main -- field 1 id -- field 2 type -- field 3 name -- field 4 contig -- field 5 start_pos -- field 6 end_pos -- field 7 strand -- field 8 description -- field 9 chrom_position -- field 10 organism -- field 11 GeneID -- header -- id type name contig start_pos end_pos strand description chrom_position organism GeneID 561276000001 SEQ_END SEQ_END NC_011900.1 2221315 2221315 DR NC_011900.1; contig end 2221315..2221315 Streptococcus pneumoniae ATCC 700669 YP_002510101.1 CDS dnaA NC_011900.1 186 1547 D binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication; can also affect transcription of multiple genes including itself.; chromosomal replication initiation protein 186..1547 Streptococcus pneumoniae ATCC 700669 7329487 YP_002510102.1 CDS dnaN NC_011900.1 1706 2842 D binds the polymerase to DNA and acts as a sliding clamp; DNA polymerase III subunit beta 1706..2842 Streptococcus pneumoniae ATCC 700669 7329237 YP_002510103.1 CDS SPN23F_00030 NC_011900.1 2907 3101 D hypothetical protein 2907..3101 Streptococcus pneumoniae ATCC 700669 7329246 YP_002510104.1 CDS SPN23F_00040 NC_011900.1 3185 4300 D translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1; GTP-dependent nucleic acid-binding protein EngD 3185..4300 Streptococcus pneumoniae ATCC 700669 7329567 YP_002510105.1 CDS pth NC_011900.1 4372 4941 D Enables the recycling of peptidyl-tRNAs produced at termination of translation; peptidyl-tRNA hydrolase 4372..4941 Streptococcus pneumoniae ATCC 700669 7329568 YP_002510106.1 CDS trcF NC_011900.1 4942 8451 D transcription-repair coupling factor 4942..8451 Streptococcus pneumoniae ATCC 700669 7327891 YP_002510107.1 CDS SPN23F_00070 NC_011900.1 8509 8775 D S4 domain containing protein 8509..8775 Streptococcus pneumoniae ATCC 700669 7327582 YP_002510108.1 CDS SPN23F_00080 NC_011900.1 8768 9136 D septum formation initiator protein 8768..9136 Streptococcus pneumoniae ATCC 700669 7329569 YP_002510109.1 CDS SPN23F_00090 NC_011900.1 9141 9263 D hypothetical protein 9141..9263 Streptococcus pneumoniae ATCC 700669 7329570 YP_002510110.1 CDS SPN23F_00100 NC_011900.1 9256 10524 D hypothetical protein 9256..10524 Streptococcus pneumoniae ATCC 700669 7329571 YP_002510111.1 CDS SPN23F_00110 NC_011900.1 10521 11798 D ATP-binding PP-loop family protein 10521..11798 Streptococcus pneumoniae ATCC 700669 7329572 YP_002510112.1 CDS hpt NC_011900.1 11802 12344 D hypoxanthine-guanine phosphoribosyltransferase 11802..12344 Streptococcus pneumoniae ATCC 700669 7329573 YP_002510113.1 CDS ftsH NC_011900.1 12360 14318 D cell division protease FtsH 12360..14318 Streptococcus pneumoniae ATCC 700669 7328075 YP_002510114.1 CDS SPN23F_00140 NC_011900.1 14384 15640 R IS1167 transposase complement(14384..15640) Streptococcus pneumoniae ATCC 700669 7328569 YP_002510115.1 CDS comX NC_011900.1 15863 16342 D competence-specific global transcription modulator 15863..16342 Streptococcus pneumoniae ATCC 700669 7329574 YP_002510116.1 CDS SPN23F_00220 NC_011900.1 23778 24014 D hypothetical protein 23778..24014 Streptococcus pneumoniae ATCC 700669 7329576 YP_002510117.1 CDS purA NC_011900.1 24245 25531 D catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis; adenylosuccinate synthetase 24245..25531 Streptococcus pneumoniae ATCC 700669 7329577 YP_002510118.1 CDS SPN23F_00240 NC_011900.1 25732 26199 D deaminase 25732..26199 Streptococcus pneumoniae ATCC 700669 7327896 YP_002510119.1 CDS SPN23F_00270 NC_011900.1 27604 28674 R type I restriction enzyme related protein complement(27604..28674) Streptococcus pneumoniae ATCC 700669 7329579 YP_002510120.1 CDS SPN23F_00280 NC_011900.1 28691 29071 R hypothetical protein complement(28691..29071) Streptococcus pneumoniae ATCC 700669 7329580 YP_002510121.1 CDS SPN23F_00290 NC_011900.1 29084 29347 R plasmid stabilisation system protein complement(29084..29347) Streptococcus pneumoniae ATCC 700669 7329581 YP_002510122.1 CDS SPN23F_00300 NC_011900.1 29347 29580 R hypothetical protein complement(29347..29580) Streptococcus pneumoniae ATCC 700669 7329582 YP_002510123.1 CDS SPN23F_00310 NC_011900.1 29580 29948 R phage DNA-binding protein complement(29580..29948) Streptococcus pneumoniae ATCC 700669 7329583 YP_002510124.1 CDS SPN23F_00320 NC_011900.1 30246 30377 D hypothetical protein 30246..30377 Streptococcus pneumoniae ATCC 700669 7329584 YP_002510125.1 CDS SPN23F_00330 NC_011900.1 30520 30711 D DNA-binding protein 30520..30711 Streptococcus pneumoniae ATCC 700669 7329585 YP_002510126.1 CDS SPN23F_00340 NC_011900.1 30734 30937 D hypothetical protein 30734..30937 Streptococcus pneumoniae ATCC 700669 7329586 YP_002510127.1 CDS SPN23F_00350 NC_011900.1 31092 31259 R hypothetical protein complement(31092..31259) Streptococcus pneumoniae ATCC 700669 7329587 YP_002510128.1 CDS SPN23F_00380 NC_011900.1 31864 32043 R hypothetical protein mw1055; DNA-binding protein complement(31864..32043) Streptococcus pneumoniae ATCC 700669 7329590 YP_002510129.1 CDS dut NC_011900.1 32639 33082 D catalyzes the formation of dUMP from dUTP; deoxyuridine 5'-triphosphate nucleotidohydrolase 32639..33082 Streptococcus pneumoniae ATCC 700669 7329591 YP_002510130.1 CDS SPN23F_00400 NC_011900.1 33084 33599 D phosphoglycerate mutase family protein 33084..33599 Streptococcus pneumoniae ATCC 700669 7329592 YP_002510131.1 CDS sms NC_011900.1 33712 34974 D Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents; DNA repair protein RadA 33712..34974 Streptococcus pneumoniae ATCC 700669 7329593 YP_002510132.1 CDS SPN23F_00420 NC_011900.1 35047 35544 D carbonic anhydrase 35047..35544 Streptococcus pneumoniae ATCC 700669 7329146 YP_002510133.1 CDS prsA1 NC_011900.1 36497 37465 D catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP; ribose-phosphate pyrophosphokinase 36497..37465 Streptococcus pneumoniae ATCC 700669 7329024 YP_002510134.1 CDS polA NC_011900.1 39119 41752 D has 3'-5' exonuclease, 5'-3' exonuclease and 5'-3'polymerase activities, primarily functions to fill gaps during DNA replication and repair; DNA polymerase I 39119..41752 Streptococcus pneumoniae ATCC 700669 7329026 YP_002510135.1 CDS SPN23F_00500 NC_011900.1 41837 42274 D CoA-binding protein 41837..42274 Streptococcus pneumoniae ATCC 700669 7327863 YP_002510136.1 CDS SPN23F_00520 NC_011900.1 42549 43559 R hypothetical protein complement(42549..43559) Streptococcus pneumoniae ATCC 700669 7329028 YP_002510137.1 CDS SPN23F_00530 NC_011900.1 43708 44877 D catalyzes the transamination of the aromatic amino acid forming a ketoacid; first step in aromatic amino acid degradation in lactococci; aromatic amino acid aminotransferase 43708..44877 Streptococcus pneumoniae ATCC 700669 7329029 YP_002510138.1 CDS recO NC_011900.1 44874 45644 D involved in DNA repair and RecFOR pathway recombination; RecFOR proteins displace ssDNA-binding protein and facilitate the production of RecA-coated ssDNA; DNA repair protein RecO 44874..45644 Streptococcus pneumoniae ATCC 700669 7329030 YP_002510139.1 CDS plsX NC_011900.1 45641 46633 D involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsY; glycerol-3-phosphate acyltransferase PlsX 45641..46633 Streptococcus pneumoniae ATCC 700669 7327446 YP_002510140.1 CDS SPN23F_00560 NC_011900.1 46639 46872 D acyl carrier protein 46639..46872 Streptococcus pneumoniae ATCC 700669 7327852 YP_002510141.1 CDS blpO NC_011900.1 47411 47641 D bacteriocin BlpO 47411..47641 Streptococcus pneumoniae ATCC 700669 7329032 YP_002510142.1 CDS SPN23F_00580 NC_011900.1 47644 47769 D hypothetical protein 47644..47769 Streptococcus pneumoniae ATCC 700669 7328692 YP_002510143.1 CDS SPN23F_00590 NC_011900.1 48356 50509 D bacteriocin transport/processing ATP-binding protein 48356..50509 Streptococcus pneumoniae ATCC 700669 7329033 YP_002510144.1 CDS SPN23F_00600 NC_011900.1 50522 51871 D bacteriocin transport accessory protein 50522..51871 Streptococcus pneumoniae ATCC 700669 7329034 YP_002510145.1 CDS purC NC_011900.1 52041 52748 D catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis; SAICAR synthase; phosphoribosylaminoimidazole-succinocarboxamide synthase 52041..52748 Streptococcus pneumoniae ATCC 700669 7329035 YP_002510146.1 CDS SPN23F_00620 NC_011900.1 52805 56530 D phosphoribosylformylglycinamidine synthase protein 52805..56530 Streptococcus pneumoniae ATCC 700669 7327898 YP_002510147.1 CDS purF NC_011900.1 56623 58065 D Catalyzes first step of the de novo purine nucleotide biosynthetic pathway; amidophosphoribosyltransferase 56623..58065 Streptococcus pneumoniae ATCC 700669 7329036 YP_002510148.1 CDS purM NC_011900.1 58102 59124 D catalyzes the formation of 1-(5-phosphoribosyl)-5-aminoimidazole from 2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in purine biosynthesis; phosphoribosylaminoimidazole synthetase 58102..59124 Streptococcus pneumoniae ATCC 700669 7327421 YP_002510149.1 CDS purN NC_011900.1 59121 59666 D glycinamide ribonucleotide transformylase; GAR Tfase; catalyzes the synthesis of 5'-phosphoribosylformylglycinamide from 5'-phosphoribosylglycinamide and 10-formyltetrahydrofolate; PurN requires formyl folate for the reaction unlike PurT which uses formate; phosphoribosylglycinamide formyltransferase 59121..59666 Streptococcus pneumoniae ATCC 700669 7327424 YP_002510150.1 CDS vanZ NC_011900.1 59750 60259 D This gene gives low level resistance and is seperate from the 5 gene vancomysin resistance cluster on Tn1546. Forms a low GC trough.; VanZ-family resistance protein 59750..60259 Streptococcus pneumoniae ATCC 700669 7327425 YP_002510151.1 CDS purH NC_011900.1 60284 61831 D involved in de novo purine biosynthesis; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 60284..61831 Streptococcus pneumoniae ATCC 700669 7329427 YP_002510152.1 CDS purD NC_011900.1 61953 63215 D catalyzes the formation of N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-D-ribosylamine and glycine in purine biosynthesis; phosphoribosylamine--glycine ligase 61953..63215 Streptococcus pneumoniae ATCC 700669 7327422 YP_002510153.1 CDS purE NC_011900.1 63585 64106 D phosphoribosylaminoimidazole carboxylase catalytic subunit 63585..64106 Streptococcus pneumoniae ATCC 700669 7327419 YP_002510154.1 CDS purK NC_011900.1 64093 65166 D With PurE catalyzes the conversion of aminoimidazole ribonucleotide to carboxyaminoimidazole ribonucleotide in the de novo purine nucleotide biosynthetic pathway; phosphoribosylaminoimidazole carboxylase ATPase subunit 64093..65166 Streptococcus pneumoniae ATCC 700669 7327420 YP_002510155.1 CDS SPN23F_00710 NC_011900.1 65189 67576 D ATP/GTP binding protein 65189..67576 Streptococcus pneumoniae ATCC 700669 7327423 YP_002510156.1 CDS purB NC_011900.1 67749 69047 D Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide; adenylosuccinate lyase 67749..69047 Streptococcus pneumoniae ATCC 700669 7329037 YP_002510157.1 CDS strH NC_011900.1 69102 73040 R beta-N-acetylhexosaminidase precursor complement(69102..73040) Streptococcus pneumoniae ATCC 700669 7327897 YP_002510158.1 CDS SPN23F_00740 NC_011900.1 73355 74098 R GntR family transcriptional regulator complement(73355..74098) Streptococcus pneumoniae ATCC 700669 7329158 YP_002510159.1 CDS SPN23F_00750 NC_011900.1 74419 76206 D beta-galactosidase 74419..76206 Streptococcus pneumoniae ATCC 700669 7329038 YP_002510160.1 CDS SPN23F_00760 NC_011900.1 76203 76679 D sugar phosphotransferase system (PTS), sorbose subfamily, IIB component 76203..76679 Streptococcus pneumoniae ATCC 700669 7329039 YP_002510161.1 CDS SPN23F_00770 NC_011900.1 76707 77612 D sugar phosphotransferase system (PTS),sorbose-specific family, IIC component 76707..77612 Streptococcus pneumoniae ATCC 700669 7329040 YP_002510162.1 CDS SPN23F_00780 NC_011900.1 77599 78414 D sugar phosphotransferase system (PTS),mannose/fructose/sorbose family, IID component 77599..78414 Streptococcus pneumoniae ATCC 700669 7329041 YP_002510163.1 CDS SPN23F_00790 NC_011900.1 78487 78825 D sugar phosphotransferase system (PTS), fructose family, IIA component 78487..78825 Streptococcus pneumoniae ATCC 700669 7329042 YP_002510164.1 CDS agaS NC_011900.1 79078 80244 D tagatose-6-phosphate aldose/ketose isomerase 79078..80244 Streptococcus pneumoniae ATCC 700669 7329043 YP_002510165.1 CDS SPN23F_00810 NC_011900.1 80360 81397 D aldose 1-epimerase 80360..81397 Streptococcus pneumoniae ATCC 700669 7328641 YP_002510166.1 CDS SPN23F_00820 NC_011900.1 81605 82459 D glyoxalase/bleomycin resistance protein/dioxygenase superfamily protein 81605..82459 Streptococcus pneumoniae ATCC 700669 7329044 YP_002510167.1 CDS SPN23F_00830 NC_011900.1 82644 82853 D hypothetical protein 82644..82853 Streptococcus pneumoniae ATCC 700669 7329045 YP_002510168.1 CDS SPN23F_00840 NC_011900.1 82895 83257 R hypothetical protein complement(82895..83257) Streptococcus pneumoniae ATCC 700669 7329046 YP_002510169.1 CDS SPN23F_00850 NC_011900.1 83311 83607 R hypothetical protein complement(83311..83607) Streptococcus pneumoniae ATCC 700669 7329047 YP_002510170.1 CDS SPN23F_00870 NC_011900.1 83828 84592 D phosphorylase family protein 83828..84592 Streptococcus pneumoniae ATCC 700669 7329049 YP_002510171.1 CDS SPN23F_00880 NC_011900.1 84848 85033 D hypothetical protein 84848..85033 Streptococcus pneumoniae ATCC 700669 7329050 YP_002510172.1 CDS SPN23F_00890 NC_011900.1 85202 86581 D TrkH-family cation transport protein 85202..86581 Streptococcus pneumoniae ATCC 700669 7329051 YP_002510173.1 CDS SPN23F_00900 NC_011900.1 86595 87260 D TrkA family cation transport protein 86595..87260 Streptococcus pneumoniae ATCC 700669 7329052 YP_002510174.1 CDS SPN23F_00910 NC_011900.1 87395 87553 D hypothetical protein 87395..87553 Streptococcus pneumoniae ATCC 700669 7329053 YP_002510175.1 CDS SPN23F_00950 NC_011900.1 90409 91107 D response regulator protein 90409..91107 Streptococcus pneumoniae ATCC 700669 7329056 YP_002510176.1 CDS SPN23F_00960 NC_011900.1 91104 92156 D histidine kinase protein 91104..92156 Streptococcus pneumoniae ATCC 700669 7329057 YP_002510177.1 CDS rpsD NC_011900.1 92351 92962 D primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination; 30S ribosomal protein S4 92351..92962 Streptococcus pneumoniae ATCC 700669 7329058 YP_002510178.1 CDS SPN23F_01020 NC_011900.1 94377 95306 D binding-protein-dependent transport system membrane protein 94377..95306 Streptococcus pneumoniae ATCC 700669 7329061 YP_002510179.1 CDS SPN23F_01030 NC_011900.1 95320 96243 D binding-protein-dependent transport system membrane protein 95320..96243 Streptococcus pneumoniae ATCC 700669 7329062 YP_002510180.1 CDS SPN23F_01040 NC_011900.1 96453 97928 D extracellular solute-binding protein 96453..97928 Streptococcus pneumoniae ATCC 700669 7329063 YP_002510181.1 CDS SPN23F_01050 NC_011900.1 98200 99186 D hypothetical protein 98200..99186 Streptococcus pneumoniae ATCC 700669 7329064 YP_002510182.1 CDS SPN23F_01060 NC_011900.1 99460 100320 D hypothetical protein 99460..100320 Streptococcus pneumoniae ATCC 700669 7329065 YP_002510183.1 CDS SPN23F_01070 NC_011900.1 100392 101456 R hypothetical protein complement(100392..101456) Streptococcus pneumoniae ATCC 700669 7329066 YP_002510184.1 CDS SPN23F_01080 NC_011900.1 101518 102429 R hypothetical protein complement(101518..102429) Streptococcus pneumoniae ATCC 700669 7329067 YP_002510185.1 CDS SPN23F_01090 NC_011900.1 102422 103015 R hypothetical protein complement(102422..103015) Streptococcus pneumoniae ATCC 700669 7329068 YP_002510186.1 CDS SPN23F_01100 NC_011900.1 103002 103328 R PadR family transcriptional regulator complement(103002..103328) Streptococcus pneumoniae ATCC 700669 7329069 YP_002510187.1 CDS SPN23F_01130 NC_011900.1 104690 105847 D glycosyl transferase 104690..105847 Streptococcus pneumoniae ATCC 700669 7329072 YP_002510188.1 CDS SPN23F_01140 NC_011900.1 105889 107739 D polysaccharide biosynthesis protein 105889..107739 Streptococcus pneumoniae ATCC 700669 7329073 YP_002510189.1 CDS SPN23F_01150 NC_011900.1 107779 109035 R IS1167 transposase complement(107779..109035) Streptococcus pneumoniae ATCC 700669 7329074 YP_002510190.1 CDS SPN23F_01160 NC_011900.1 109187 109393 R hypothetical protein complement(109187..109393) Streptococcus pneumoniae ATCC 700669 7329075 YP_002510191.1 CDS SPN23F_01170 NC_011900.1 109510 110142 R 5'-nucleotidase complement(109510..110142) Streptococcus pneumoniae ATCC 700669 7329076 YP_002510192.1 CDS sdhA NC_011900.1 110164 111036 R L-serine dehydratase, alpha chain complement(110164..111036) Streptococcus pneumoniae ATCC 700669 7329077 YP_002510193.1 CDS sdhB NC_011900.1 111045 111716 R L-serine dehydratase, beta chain complement(111045..111716) Streptococcus pneumoniae ATCC 700669 7329138 YP_002510194.1 CDS SPN23F_01200 NC_011900.1 111958 112545 D peptidoglycan-binding protein 111958..112545 Streptococcus pneumoniae ATCC 700669 7329139 YP_002510195.1 CDS SPN23F_01202 NC_011900.1 113349 113636 D bacteriocin 113349..113636 Streptococcus pneumoniae ATCC 700669 7329085 YP_002510196.1 CDS SPN23F_01210 NC_011900.1 113688 115796 D hypothetical protein 113688..115796 Streptococcus pneumoniae ATCC 700669 7329080 YP_002510197.1 CDS SPN23F_01220 NC_011900.1 115793 116434 D ABC transporter ATP-binding protein 115793..116434 Streptococcus pneumoniae ATCC 700669 7329081 YP_002510198.1 CDS SPN23F_01230 NC_011900.1 116641 117447 D extracellular amino acid-binding protein 116641..117447 Streptococcus pneumoniae ATCC 700669 7329082 YP_002510199.1 CDS SPN23F_01250 NC_011900.1 119110 120366 R transposase complement(119110..120366) Streptococcus pneumoniae ATCC 700669 7329079 YP_002510200.1 CDS SPN23F_01270 NC_011900.1 121031 121759 D hypothetical protein 121031..121759 Streptococcus pneumoniae ATCC 700669 7329087 YP_002510201.1 CDS SPN23F_01280 NC_011900.1 122894 123133 D hypothetical protein 122894..123133 Streptococcus pneumoniae ATCC 700669 7329088 YP_002510202.1 CDS mnmA NC_011900.1 126259 127380 D catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs; tRNA-specific 2-thiouridylase MnmA 126259..127380 Streptococcus pneumoniae ATCC 700669 7327883 YP_002510203.1 CDS SPN23F_01330 NC_011900.1 127521 127976 D MutT/NUDIX hydrolase family protein 127521..127976 Streptococcus pneumoniae ATCC 700669 7329090 YP_002510204.1 CDS gidA NC_011900.1 127986 129899 D GidA; glucose-inhibited cell division protein A; involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U) of the wobble uridine base in some tRNAs; tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA 127986..129899 Streptococcus pneumoniae ATCC 700669 7329091 YP_002510205.1 CDS SPN23F_01350 NC_011900.1 130278 131957 R metallo-beta-lactamase superfamily protein complement(130278..131957) Streptococcus pneumoniae ATCC 700669 7328592 YP_002510206.1 CDS SPN23F_01360 NC_011900.1 131959 132192 R hypothetical protein complement(131959..132192) Streptococcus pneumoniae ATCC 700669 7329092 YP_002510207.1 CDS SPN23F_01370 NC_011900.1 133010 133162 R hypothetical protein complement(133010..133162) Streptococcus pneumoniae ATCC 700669 7329190 YP_002510208.1 CDS SPN23F_01380 NC_011900.1 133164 133349 R hypothetical protein complement(133164..133349) Streptococcus pneumoniae ATCC 700669 7329094 YP_002510209.1 CDS SPN23F_01390 NC_011900.1 133527 134210 D glycoprotease family protein 133527..134210 Streptococcus pneumoniae ATCC 700669 7329095 YP_002510210.1 CDS SPN23F_01400 NC_011900.1 134207 134644 D GNAT family acetyltransferase 134207..134644 Streptococcus pneumoniae ATCC 700669 7329096 YP_002510211.1 CDS SPN23F_01410 NC_011900.1 134634 135644 D in most organisms, only the N-terminal domain is present in a single polypeptide; in some archaea this domain is fused to a kinase domain; this gene is essential for growth in Escherichia coli and Bacillus subtilis; the secreted glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins; the Pyrococcus structure shows DNA-binding properties, iron-binding, ATP-binding, and AP endonuclease activity; DNA-binding/iron metalloprotein/AP endonuclease 134634..135644 Streptococcus pneumoniae ATCC 700669 7329097 YP_002510212.1 CDS SPN23F_01430 NC_011900.1 136061 136990 R transposase complement(136061..136990) Streptococcus pneumoniae ATCC 700669 7329099 YP_002510213.1 CDS SPN23F_01460 NC_011900.1 139459 140412 D glycosyl transferase 139459..140412 Streptococcus pneumoniae ATCC 700669 7327902 YP_002510214.1 CDS SPN23F_01470 NC_011900.1 140422 142038 D ABC transporter ATP-binding protein/permease 140422..142038 Streptococcus pneumoniae ATCC 700669 7327903 YP_002510215.1 CDS SPN23F_01490 NC_011900.1 142827 143576 D acetyltransferase 142827..143576 Streptococcus pneumoniae ATCC 700669 7327906 YP_002510216.1 CDS ugd NC_011900.1 143589 144761 D UDP-glucose 6-dehydrogenase 143589..144761 Streptococcus pneumoniae ATCC 700669 7327907 YP_002510217.1 CDS SPN23F_01510 NC_011900.1 145157 146020 D hypothetical protein 145157..146020 Streptococcus pneumoniae ATCC 700669 7327660 YP_002510218.1 CDS SPN23F_01520 NC_011900.1 146306 146506 D hypothetical protein 146306..146506 Streptococcus pneumoniae ATCC 700669 7327908 YP_002510219.1 CDS SPN23F_01530 NC_011900.1 146573 147238 D membrane protease 146573..147238 Streptococcus pneumoniae ATCC 700669 7327909 YP_002510220.1 CDS SPN23F_01540 NC_011900.1 147310 148536 D transport protein 147310..148536 Streptococcus pneumoniae ATCC 700669 7327910 YP_002510221.1 CDS SPN23F_01550 NC_011900.1 148989 149645 D AzlC-family transport protein 148989..149645 Streptococcus pneumoniae ATCC 700669 7327911 YP_002510222.1 CDS SPN23F_01560 NC_011900.1 149635 149844 D AzlD-like membrane transport protein 149635..149844 Streptococcus pneumoniae ATCC 700669 7327912 YP_002510223.1 CDS SPN23F_01570 NC_011900.1 150062 150892 D extracellular solute-binding protein 150062..150892 Streptococcus pneumoniae ATCC 700669 7327913 YP_002510224.1 CDS SPN23F_01580 NC_011900.1 151046 151900 D lipoprotein 151046..151900 Streptococcus pneumoniae ATCC 700669 7327914 YP_002510225.1 CDS SPN23F_01590 NC_011900.1 152000 153373 D peptidase 152000..153373 Streptococcus pneumoniae ATCC 700669 7327915 YP_002510226.1 CDS SPN23F_01600 NC_011900.1 153366 154427 D ABC transporter ATP-binding protein 153366..154427 Streptococcus pneumoniae ATCC 700669 7327916 YP_002510227.1 CDS SPN23F_01610 NC_011900.1 154429 155121 D ABC transporter system permease protein 154429..155121 Streptococcus pneumoniae ATCC 700669 7327917 YP_002510228.1 CDS SPN23F_01620 NC_011900.1 155151 155720 R hypothetical protein complement(155151..155720) Streptococcus pneumoniae ATCC 700669 7327918 YP_002510229.1 CDS SPN23F_01630 NC_011900.1 155855 156469 D hypothetical protein 155855..156469 Streptococcus pneumoniae ATCC 700669 7327919 YP_002510230.1 CDS SPN23F_01640 NC_011900.1 156519 158117 D histidine sensor kinase 156519..158117 Streptococcus pneumoniae ATCC 700669 7327920 YP_002510231.1 CDS SPN23F_01650 NC_011900.1 158129 159415 D response regulator protein 158129..159415 Streptococcus pneumoniae ATCC 700669 7327921 YP_002510232.1 CDS SPN23F_01660 NC_011900.1 159476 160009 D hypothetical protein 159476..160009 Streptococcus pneumoniae ATCC 700669 7327922 YP_002510233.1 CDS SPN23F_01670 NC_011900.1 160087 160557 D has a stimulatory effect on the ribonucleotide reductase activity of NrdH with NrdEF; flavoprotein NrdI 160087..160557 Streptococcus pneumoniae ATCC 700669 7327923 YP_002510234.1 CDS SPN23F_01680 NC_011900.1 160850 162112 R integral membrane protein complement(160850..162112) Streptococcus pneumoniae ATCC 700669 7327924 YP_002510235.1 CDS SPN23F_01690 NC_011900.1 162422 162880 R hypothetical protein complement(162422..162880) Streptococcus pneumoniae ATCC 700669 7327925 YP_002510236.1 CDS SPN23F_01700 NC_011900.1 162877 163317 R DNA-binding protein complement(162877..163317) Streptococcus pneumoniae ATCC 700669 7327926 YP_002510237.1 CDS mutL NC_011900.1 163673 165622 D This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. Promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex; DNA mismatch repair protein 163673..165622 Streptococcus pneumoniae ATCC 700669 7327927 YP_002510238.1 CDS ribH NC_011900.1 165947 166414 R RibE; 6,7-diimethyl-8-ribityllumazine synthase; DMRL synthase; lumazine synthase; beta subunit of riboflavin synthase; condenses 5-amino-6-(1'-D)-ribityl-amino-2,4(1H,3H)-pyrimidinedione with L-3,4-dihydrohy-2-butanone-4-phosphate to generate 6,6-dimethyl-8-lumazine (DMRL); riboflavin synthase then uses 2 molecules of DMRL to produce riboflavin (vitamin B12); involved in the last steps of riboflavin biosynthesis; forms a 60mer (icosahedral shell) in both Bacillus subtilis and Escherichia coli; in Bacillus subtilis this 60mer is associated with the riboflavin synthase subunit (alpha) while in Escherichia coli it is not; 6,7-dimethyl-8-ribityllumazine synthase complement(165947..166414) Streptococcus pneumoniae ATCC 700669 7328401 YP_002510239.1 CDS ribA NC_011900.1 166415 167620 R riboflavin biosynthesis protein complement(166415..167620) Streptococcus pneumoniae ATCC 700669 7327456 YP_002510240.1 CDS ribE NC_011900.1 167640 168275 R catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine; riboflavin synthase subunit alpha complement(167640..168275) Streptococcus pneumoniae ATCC 700669 7327452 YP_002510241.1 CDS ribD NC_011900.1 168260 169360 R riboflavin biosynthesis protein complement(168260..169360) Streptococcus pneumoniae ATCC 700669 7327455 YP_002510242.1 CDS ruvA NC_011900.1 169765 170358 D plays an essential role in ATP-dependent branch migration of the Holliday junction; Holliday junction DNA helicase RuvA 169765..170358 Streptococcus pneumoniae ATCC 700669 7329459 YP_002510243.1 CDS tag NC_011900.1 170368 170931 D DNA-3-methyladenine glycosylase I 170368..170931 Streptococcus pneumoniae ATCC 700669 7329129 YP_002510244.1 CDS SPN23F_01780 NC_011900.1 170928 171605 D protease 170928..171605 Streptococcus pneumoniae ATCC 700669 7329162 YP_002510245.1 CDS SPN23F_01790 NC_011900.1 171742 172773 R carboxypeptidase complement(171742..172773) Streptococcus pneumoniae ATCC 700669 7327928 YP_002510246.1 CDS SPN23F_01800 NC_011900.1 173028 173711 R hypothetical protein complement(173028..173711) Streptococcus pneumoniae ATCC 700669 7327929 YP_002510247.1 CDS SPN23F_01810 NC_011900.1 173723 174667 R CorA-like Mg2+ transporter protein complement(173723..174667) Streptococcus pneumoniae ATCC 700669 7327930 YP_002510248.1 CDS uvrA NC_011900.1 174799 177630 D The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate; excinuclease ABC subunit A 174799..177630 Streptococcus pneumoniae ATCC 700669 7327931 YP_002510249.1 CDS SPN23F_01830 NC_011900.1 177623 178684 D metallopeptidase 177623..178684 Streptococcus pneumoniae ATCC 700669 7329423 YP_002510250.1 CDS spxA NC_011900.1 178816 179214 D the anti-alpha factor Spx interacts with RNA polymerase alpha subunit C-terminal domain in a region that interacts with the sigma 70 subunit and may interfere with activation of promoters; in Bacillus subtilis this protein is a substrate for ClpXP protease; blocks transcription of the competence regulatory gene encoded by the srf operon; regulates a number of genes involved in thiol homeostasis including trxA and trxB; monomeric member of ArsC family of proteins; does not bind DNA; contains a disulfide bond between C10 and C13 which may sense disulfide stress; Spx family transcriptional regulator 178816..179214 Streptococcus pneumoniae ATCC 700669 7327932 YP_002510251.1 CDS SPN23F_01850 NC_011900.1 179280 179849 D lipoprotein 179280..179849 Streptococcus pneumoniae ATCC 700669 7327933 YP_002510252.1 CDS SPN23F_01860 NC_011900.1 179936 180202 D hypothetical protein 179936..180202 Streptococcus pneumoniae ATCC 700669 7327934 YP_002510253.1 CDS SPN23F_01870 NC_011900.1 180215 180625 D similar to RuvC resolvase with substantial differences; NMR structural information suggests this protein is monomeric; unknown cellular function; Holliday junction resolvase-like protein 180215..180625 Streptococcus pneumoniae ATCC 700669 7327935 YP_002510254.1 CDS SPN23F_01880 NC_011900.1 180641 180946 D hypothetical protein 180641..180946 Streptococcus pneumoniae ATCC 700669 7327936 YP_002510255.1 CDS SPN23F_01890 NC_011900.1 181204 182454 D folylpolyglutamate synthase 181204..182454 Streptococcus pneumoniae ATCC 700669 7327937 YP_002510256.1 CDS SPN23F_01900 NC_011900.1 182538 182993 D lipoprotein 182538..182993 Streptococcus pneumoniae ATCC 700669 7327938 YP_002510257.1 CDS SPN23F_01910 NC_011900.1 183139 184671 D cardiolipin synthetase 183139..184671 Streptococcus pneumoniae ATCC 700669 7327939 YP_002510258.1 CDS SPN23F_01920 NC_011900.1 184929 186467 D hypothetical protein 184929..186467 Streptococcus pneumoniae ATCC 700669 7327940 YP_002510259.1 CDS nrdD NC_011900.1 186587 188794 D Catalyzes the reduction of nucleoside 5'-triphosphates to 2'-deoxynucleoside 5'-triphosphates; anaerobic ribonucleoside triphosphate reductase 186587..188794 Streptococcus pneumoniae ATCC 700669 7327941 YP_002510260.1 CDS SPN23F_01940 NC_011900.1 188806 188946 D hypothetical protein 188806..188946 Streptococcus pneumoniae ATCC 700669 7328422 YP_002510261.1 CDS SPN23F_01950 NC_011900.1 188990 189496 D GNAT family acetyltransferase 188990..189496 Streptococcus pneumoniae ATCC 700669 7327942 YP_002510262.1 CDS nrdG NC_011900.1 189489 190079 D anaerobic ribonucleoside-triphosphate reductase activating protein 189489..190079 Streptococcus pneumoniae ATCC 700669 7327943 YP_002510263.1 CDS SPN23F_01970 NC_011900.1 190076 190693 D phosphoribulokinase 190076..190693 Streptococcus pneumoniae ATCC 700669 7328423 YP_002510264.1 CDS rpsJ NC_011900.1 190960 191268 D NusE; involved in assembly of the 30S subunit; in the ribosome, this protein is involved in the binding of tRNA; in Escherichia coli this protein was also found to be involved in transcription antitermination; NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination; binding of NusB/S10 to boxA nucleates assembly of the antitermination complex; 30S ribosomal protein S10 190960..191268 Streptococcus pneumoniae ATCC 700669 7327944 YP_002510265.1 CDS rplC NC_011900.1 191484 192110 D binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin; 50S ribosomal protein L3 191484..192110 Streptococcus pneumoniae ATCC 700669 7329117 YP_002510266.1 CDS rplD NC_011900.1 192135 192758 D L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA; 50S ribosomal protein L4 192135..192758 Streptococcus pneumoniae ATCC 700669 7327472 YP_002510267.1 CDS rplW NC_011900.1 192758 193054 D binds third domain of 23S rRNA and protein L29; part of exit tunnel; 50S ribosomal protein L23 192758..193054 Streptococcus pneumoniae ATCC 700669 7327473 YP_002510268.1 CDS rplB NC_011900.1 193072 193905 D one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation; 50S ribosomal protein L2 193072..193905 Streptococcus pneumoniae ATCC 700669 7327490 YP_002510269.1 CDS rpsS NC_011900.1 194009 194290 D protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA; 30S ribosomal protein S19 194009..194290 Streptococcus pneumoniae ATCC 700669 7327471 YP_002510270.1 CDS rplV NC_011900.1 194302 194646 D binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center; 50S ribosomal protein L22 194302..194646 Streptococcus pneumoniae ATCC 700669 7329125 YP_002510271.1 CDS rpsC NC_011900.1 194659 195312 D forms a complex with S10 and S14; binds the lower part of the 30S subunit head and the mRNA in the complete ribosome to position it for translation; 30S ribosomal protein S3 194659..195312 Streptococcus pneumoniae ATCC 700669 7327489 YP_002510272.1 CDS rplP NC_011900.1 195316 195729 D located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e; 50S ribosomal protein L16 195316..195729 Streptococcus pneumoniae ATCC 700669 7329110 YP_002510273.1 CDS rpmC NC_011900.1 195739 195945 D one of the stabilizing components for the large ribosomal subunit; 50S ribosomal protein L29 195739..195945 Streptococcus pneumoniae ATCC 700669 7327483 YP_002510274.1 CDS rpsQ NC_011900.1 195970 196230 D primary binding protein; helps mediate assembly; involved in translation fidelity; 30S ribosomal protein S17 195970..196230 Streptococcus pneumoniae ATCC 700669 7327494 YP_002510275.1 CDS rplN NC_011900.1 196256 196624 D binds to the 23S rRNA between the centers for peptidyl transferase and GTPase; 50S ribosomal protein L14 196256..196624 Streptococcus pneumoniae ATCC 700669 7329123 YP_002510276.1 CDS rplX NC_011900.1 196702 197007 D assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel; 50S ribosomal protein L24 196702..197007 Streptococcus pneumoniae ATCC 700669 7327481 YP_002510277.1 CDS rplE NC_011900.1 197031 197573 D part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13; 50S ribosomal protein L5 197031..197573 Streptococcus pneumoniae ATCC 700669 7327491 YP_002510278.1 CDS rpsN NC_011900.1 197591 197860 D located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group do not appear to have the zinc-binding motif; 30S ribosomal protein S14 197591..197860 Streptococcus pneumoniae ATCC 700669 7327474 YP_002510279.1 CDS rpsH NC_011900.1 198145 198543 D binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; 30S ribosomal protein S8 198145..198543 Streptococcus pneumoniae ATCC 700669 7327945 YP_002510280.1 CDS rplF NC_011900.1 198735 199271 D ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance; 50S ribosomal protein L6 198735..199271 Streptococcus pneumoniae ATCC 700669 7329115 YP_002510281.1 CDS rplR NC_011900.1 199355 199711 D binds 5S rRNA along with protein L5 and L25; 50S ribosomal protein L18 199355..199711 Streptococcus pneumoniae ATCC 700669 7327475 YP_002510282.1 CDS rpsE NC_011900.1 199729 200223 D located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance; 30S ribosomal protein S5 199729..200223 Streptococcus pneumoniae ATCC 700669 7327485 YP_002510283.1 CDS rpmD NC_011900.1 200237 200419 D L30 binds domain II of the 23S rRNA and the 5S rRNA; similar to eukaryotic protein L7; 50S ribosomal protein L30 200237..200419 Streptococcus pneumoniae ATCC 700669 7329112 YP_002510284.1 CDS rplO NC_011900.1 200564 201004 D late assembly protein; 50S ribosomal protein L15 200564..201004 Streptococcus pneumoniae ATCC 700669 7327495 YP_002510285.1 CDS secY NC_011900.1 201017 202327 D forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase; preprotein translocase subunit SecY 201017..202327 Streptococcus pneumoniae ATCC 700669 7327482 YP_002510286.1 CDS adk NC_011900.1 202478 203116 D essential enzyme that recycles AMP in active cells; converts ATP and AMP to two molecules of ADP; adenylate kinase 202478..203116 Streptococcus pneumoniae ATCC 700669 7329142 YP_002510287.1 CDS infA NC_011900.1 203233 203451 D stimulates the activities of the other two initiation factors, IF-2 and IF-3; translation initiation factor IF-1 203233..203451 Streptococcus pneumoniae ATCC 700669 7328638 YP_002510288.1 CDS rpsM NC_011900.1 203610 203975 D located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA; 30S ribosomal protein S13 203610..203975 Streptococcus pneumoniae ATCC 700669 7328085 YP_002510289.1 CDS rpsK NC_011900.1 203993 204376 D located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3; 30S ribosomal protein S11 203993..204376 Streptococcus pneumoniae ATCC 700669 7329120 YP_002510290.1 CDS rpoA NC_011900.1 204419 205354 D catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme; DNA-directed RNA polymerase subunit alpha 204419..205354 Streptococcus pneumoniae ATCC 700669 7329118 YP_002510291.1 CDS rplQ NC_011900.1 205366 205752 D is a component of the macrolide binding site in the peptidyl transferase center; 50S ribosomal protein L17 205366..205752 Streptococcus pneumoniae ATCC 700669 7329103 YP_002510292.1 CDS SPN23F_02260 NC_011900.1 206017 206283 D ACT domain-containing protein; hypothetical protein 206017..206283 Streptococcus pneumoniae ATCC 700669 7327484 YP_002510293.1 CDS SPN23F_02270 NC_011900.1 206293 207630 D hypothetical protein 206293..207630 Streptococcus pneumoniae ATCC 700669 7327946 YP_002510294.1 CDS SPN23F_02280 NC_011900.1 207874 208566 D phosphoglycerate mutase family protein 207874..208566 Streptococcus pneumoniae ATCC 700669 7327947 YP_002510295.1 CDS SPN23F_02290 NC_011900.1 208669 209082 R ABC transporter permease complement(208669..209082) Streptococcus pneumoniae ATCC 700669 7327948 YP_002510296.1 CDS SPN23F_02300 NC_011900.1 209079 209651 R inner membrane component of ABC transporter complement(209079..209651) Streptococcus pneumoniae ATCC 700669 7327949 YP_002510297.1 CDS SPN23F_02310 NC_011900.1 209678 210304 R ABC transporter permease complement(209678..210304) Streptococcus pneumoniae ATCC 700669 7327950 YP_002510298.1 CDS SPN23F_02320 NC_011900.1 210294 211385 R ATP-binding component of ABC transporter complement(210294..211385) Streptococcus pneumoniae ATCC 700669 7327951 YP_002510299.1 CDS SPN23F_02341 NC_011900.1 212736 212933 R AraC family transcriptional regulator complement(212736..212933) Streptococcus pneumoniae ATCC 700669 7327953 YP_002510300.1 CDS SPN23F_02350 NC_011900.1 213008 213784 R pyruvate formate-lyase activating enzyme complement(213008..213784) Streptococcus pneumoniae ATCC 700669 7327954 YP_002510301.1 CDS SPN23F_02360 NC_011900.1 213906 214652 D DeoR family regulatory protein 213906..214652 Streptococcus pneumoniae ATCC 700669 7327955 YP_002510302.1 CDS SPN23F_02370 NC_011900.1 214665 215645 D sugar-binding regulatory protein 214665..215645 Streptococcus pneumoniae ATCC 700669 7327956 YP_002510303.1 CDS SPN23F_02380 NC_011900.1 215840 216160 D sugar phosphotransferase system (PTS),lactose/cellobiose-specific family, IIA component 215840..216160 Streptococcus pneumoniae ATCC 700669 7327957 YP_002510304.1 CDS SPN23F_02390 NC_011900.1 216206 216514 D sugar phosphotransferase system (PTS),lactose/cellobiose-specific family, IIB component 216206..216514 Streptococcus pneumoniae ATCC 700669 7327958 YP_002510305.1 CDS SPN23F_02400 NC_011900.1 216531 217829 D sugar phosphotransferase system (PTS), IIC component 216531..217829 Streptococcus pneumoniae ATCC 700669 7327959 YP_002510306.1 CDS pflD NC_011900.1 217980 220418 D formate acetyltransferase 217980..220418 Streptococcus pneumoniae ATCC 700669 7327960 YP_002510307.1 CDS fsaA NC_011900.1 220437 221105 D similar to transaldolase from Escherichia coli; many organisms have multiple copies; fructose-6-phosphate aldolase 220437..221105 Streptococcus pneumoniae ATCC 700669 7327836 YP_002510308.1 CDS gldA NC_011900.1 221123 222211 D forms dimers and octamers; involved in conversion of glycerol to dihydroxy-acetone; glycerol dehydrogenase 221123..222211 Streptococcus pneumoniae ATCC 700669 7328566 YP_002510309.1 CDS leuS NC_011900.1 222666 225167 D leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase; leucyl-tRNA synthetase 222666..225167 Streptococcus pneumoniae ATCC 700669 7328595 YP_002510310.1 CDS SPN23F_02450 NC_011900.1 225361 226056 D GNAT-family acetyltransferase 225361..226056 Streptococcus pneumoniae ATCC 700669 7328105 YP_002510311.1 CDS SPN23F_02460 NC_011900.1 226068 226484 D GNAT family acetyltransferase 226068..226484 Streptococcus pneumoniae ATCC 700669 7327961 YP_002510312.1 CDS ruvB NC_011900.1 227552 228523 D promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration; Holliday junction DNA helicase RuvB 227552..228523 Streptococcus pneumoniae ATCC 700669 7327962 YP_002510313.1 CDS SPN23F_02480 NC_011900.1 228504 229076 D hypothetical protein 228504..229076 Streptococcus pneumoniae ATCC 700669 7329130 YP_002510314.1 CDS uppS NC_011900.1 229307 230065 D catalyzes the formation of undecaprenyl pyrophosphate from isopentenyl pyrophosphate; UDP pyrophosphate synthase 229307..230065 Streptococcus pneumoniae ATCC 700669 7327963 YP_002510315.1 CDS SPN23F_02500 NC_011900.1 230074 230877 D phosphatidate cytidylyltransferase 230074..230877 Streptococcus pneumoniae ATCC 700669 7329422 YP_002510316.1 CDS eep NC_011900.1 230899 232158 D pheromone-processing membrane metalloprotease 230899..232158 Streptococcus pneumoniae ATCC 700669 7327964 YP_002510317.1 CDS proS NC_011900.1 232171 234024 D catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro); prolyl-tRNA synthetase 232171..234024 Streptococcus pneumoniae ATCC 700669 7329250 YP_002510318.1 CDS SPN23F_02530 NC_011900.1 234124 235503 D beta-glucosidase 234124..235503 Streptococcus pneumoniae ATCC 700669 7327879 YP_002510319.1 CDS glmS NC_011900.1 235695 237503 D isomerizing; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source; glucosamine--fructose-6-phosphate aminotransferase 235695..237503 Streptococcus pneumoniae ATCC 700669 7327965 YP_002510320.1 CDS SPN23F_02550 NC_011900.1 237622 238671 D luciferase-like monooxygenase 237622..238671 Streptococcus pneumoniae ATCC 700669 7328601 YP_002510321.1 CDS SPN23F_02560 NC_011900.1 238771 242568 R surface-anchored pullulanase complement(238771..242568) Streptococcus pneumoniae ATCC 700669 7327966 YP_002510322.1 CDS rpsL NC_011900.1 242985 243398 D interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance; 30S ribosomal protein S12 242985..243398 Streptococcus pneumoniae ATCC 700669 7327967 YP_002510323.1 CDS rpsG NC_011900.1 243418 243888 D binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit; 30S ribosomal protein S7 243418..243888 Streptococcus pneumoniae ATCC 700669 7329119 YP_002510324.1 CDS fus NC_011900.1 244283 246364 D EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene; elongation factor G 244283..246364 Streptococcus pneumoniae ATCC 700669 7329114 YP_002510325.1 CDS polC NC_011900.1 246468 250859 D catalyzes DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time; required for leading strand synthesis; PolC exhibits 3' to 5' exonuclease activity; DNA polymerase III PolC 246468..250859 Streptococcus pneumoniae ATCC 700669 7328579 YP_002510326.1 CDS SPN23F_02610 NC_011900.1 250902 252158 R IS1167 transposase complement(250902..252158) Streptococcus pneumoniae ATCC 700669 7327864 YP_002510327.1 CDS SPN23F_02620 NC_011900.1 252385 252648 D plasmid stabilization system antitoxin protein 252385..252648 Streptococcus pneumoniae ATCC 700669 7327968 YP_002510328.1 CDS SPN23F_02650 NC_011900.1 252939 253091 D hypothetical protein 252939..253091 Streptococcus pneumoniae ATCC 700669 7327971 YP_002510329.1 CDS pepS NC_011900.1 253113 254354 D aminopeptidase PepS 253113..254354 Streptococcus pneumoniae ATCC 700669 7327972 YP_002510330.1 CDS SPN23F_02670 NC_011900.1 254364 254594 D transglycosylase 254364..254594 Streptococcus pneumoniae ATCC 700669 7327829 YP_002510331.1 CDS SPN23F_02680 NC_011900.1 254863 255585 D ribosomal small subunit pseudouridine synthase B 254863..255585 Streptococcus pneumoniae ATCC 700669 7327973 YP_002510332.1 CDS pepC NC_011900.1 255802 257136 D aminopeptidase C 255802..257136 Streptococcus pneumoniae ATCC 700669 7327974 YP_002510333.1 CDS manN NC_011900.1 257192 258103 R mannose-specific phosphotransferase system (PTS), IID component complement(257192..258103) Streptococcus pneumoniae ATCC 700669 7327825 YP_002510334.1 CDS manM NC_011900.1 258127 258930 R mannose-specific phosphotransferase system (PTS), IIC component complement(258127..258930) Streptococcus pneumoniae ATCC 700669 7328123 YP_002510335.1 CDS manL NC_011900.1 258958 259947 R mannose-specific phosphotransferase system (PTS), IIAB component complement(258958..259947) Streptococcus pneumoniae ATCC 700669 7328122 YP_002510336.1 CDS adhP NC_011900.1 260180 261199 R similar to zinc-dependent eukaryotic ADH enzymes and distinct from fermentative ADHs; alcohol dehydrogenase complement(260180..261199) Streptococcus pneumoniae ATCC 700669 7328121 YP_002510337.1 CDS SPN23F_02750 NC_011900.1 261538 262350 R haloacid dehalogenase-like hydrolase complement(261538..262350) Streptococcus pneumoniae ATCC 700669 7328637 YP_002510338.1 CDS SPN23F_02760 NC_011900.1 262540 263958 D permease 262540..263958 Streptococcus pneumoniae ATCC 700669 7327975 YP_002510339.1 CDS SPN23F_02770 NC_011900.1 264011 264718 D CAAX amino terminal protease family membrane protein 264011..264718 Streptococcus pneumoniae ATCC 700669 7327976 YP_002510340.1 CDS folP NC_011900.1 264808 265785 D dihydropteroate synthase 264808..265785 Streptococcus pneumoniae ATCC 700669 7327977 YP_002510341.1 CDS folC NC_011900.1 265787 267109 D folylpolyglutamate synthase 265787..267109 Streptococcus pneumoniae ATCC 700669 7328561 YP_002510342.1 CDS folE NC_011900.1 267090 267644 D involved in the first step of tetrahydrofolate biosynthesis; catalyzes the formation of formate and 2-amino-4-hydroxy-6-(erythro-1,2, 3-trihydroxypropyl)dihydropteridine triphosphate from GTP and water; forms a homopolymer; GTP cyclohydrolase I 267090..267644 Streptococcus pneumoniae ATCC 700669 7328558 YP_002510343.1 CDS SPN23F_02810 NC_011900.1 267803 268615 D 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase 267803..268615 Streptococcus pneumoniae ATCC 700669 7328560 YP_002510344.1 CDS SPN23F_02820 NC_011900.1 268660 268977 R hypothetical protein complement(268660..268977) Streptococcus pneumoniae ATCC 700669 7327978 YP_002510345.1 CDS rplM NC_011900.1 269334 269780 D in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit; 50S ribosomal protein L13 269334..269780 Streptococcus pneumoniae ATCC 700669 7327979 YP_002510346.1 CDS rpsI NC_011900.1 269799 270191 D forms a direct contact with the tRNA during translation; 30S ribosomal protein S9 269799..270191 Streptococcus pneumoniae ATCC 700669 7327480 YP_002510347.1 CDS SPN23F_02870 NC_011900.1 271598 273811 D glycosylhydrolase 271598..273811 Streptococcus pneumoniae ATCC 700669 7327500 YP_002510348.1 CDS SPN23F_02880 NC_011900.1 274033 274509 R glutathione peroxidase complement(274033..274509) Streptococcus pneumoniae ATCC 700669 7327501 YP_002510349.1 CDS SPN23F_02890 NC_011900.1 274732 277935 D hyaluronate lyase 274732..277935 Streptococcus pneumoniae ATCC 700669 7327502 YP_002510350.1 CDS kgdA NC_011900.1 279079 279708 R catalyzes the formation of pyruvate and glyoxylate from 4-hydroxy-2-oxoglutarate; or pyruvate and D-glyceraldehyde 3-phosphate from 2-dehydro-3-deoxy-D-glyconate 6-phosphate; keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase complement(279079..279708) Streptococcus pneumoniae ATCC 700669 7327504 YP_002510351.1 CDS SPN23F_02920 NC_011900.1 279718 280719 R PfkB family carbohydrate kinase complement(279718..280719) Streptococcus pneumoniae ATCC 700669 7328089 YP_002510352.1 CDS SPN23F_02930 NC_011900.1 280750 281391 R hypothetical protein complement(280750..281391) Streptococcus pneumoniae ATCC 700669 7327505 YP_002510353.1 CDS idnO NC_011900.1 281410 282225 R Involved in the nonphosphorylative, ketogenic oxidation of glucose and oxidizes gluconate to 5-ketogluconate; gluconate 5-dehydrogenase complement(281410..282225) Streptococcus pneumoniae ATCC 700669 7327506 YP_002510354.1 CDS SPN23F_02950 NC_011900.1 282497 282931 D N-acetylgalactosamine-specific phosphotransferase system (PTS), IIA component 282497..282931 Streptococcus pneumoniae ATCC 700669 7328079 YP_002510355.1 CDS ugl NC_011900.1 282943 284133 D unsaturated glucuronyl hydrolase 282943..284133 Streptococcus pneumoniae ATCC 700669 7327507 YP_002510356.1 CDS agaV NC_011900.1 284144 284635 D N-acetylgalactosamine-specific phosphotransferase system (PTS), IIB component 284144..284635 Streptococcus pneumoniae ATCC 700669 7327579 YP_002510357.1 CDS agaW NC_011900.1 284650 285429 D N-acetylgalactosamine-specific phosphotransferase system (PTS), IIC component 284650..285429 Streptococcus pneumoniae ATCC 700669 7328642 YP_002510358.1 CDS agaD NC_011900.1 285416 286234 D N-acetylgalactosamine-specific phosphotransferase system (PTS), IID component 285416..286234 Streptococcus pneumoniae ATCC 700669 7328643 YP_002510359.1 CDS SPN23F_03000 NC_011900.1 286261 286527 D hypothetical protein 286261..286527 Streptococcus pneumoniae ATCC 700669 7328640 YP_002510360.1 CDS SPN23F_03010 NC_011900.1 286549 288450 D heparinase II/III-like protein 286549..288450 Streptococcus pneumoniae ATCC 700669 7327508 YP_002510361.1 CDS SPN23F_03020 NC_011900.1 288510 289511 D LacI family transcriptional regulator 288510..289511 Streptococcus pneumoniae ATCC 700669 7327509 YP_002510362.1 CDS SPN23F_03030 NC_011900.1 289621 289956 R membrane protein complement(289621..289956) Streptococcus pneumoniae ATCC 700669 7327510 YP_002510363.1 CDS SPN23F_03040 NC_011900.1 289967 290209 R hypothetical protein complement(289967..290209) Streptococcus pneumoniae ATCC 700669 7327511 YP_002510364.1 CDS SPN23F_03050 NC_011900.1 290225 290419 R DNA-binding protein complement(290225..290419) Streptococcus pneumoniae ATCC 700669 7327512 YP_002510365.1 CDS mraW NC_011900.1 290585 291535 D S-adenosyl-methyltransferase MraW 290585..291535 Streptococcus pneumoniae ATCC 700669 7327513 YP_002510366.1 CDS ftsL NC_011900.1 291547 291864 D cell division protein 291547..291864 Streptococcus pneumoniae ATCC 700669 7328131 YP_002510367.1 CDS pbpX NC_011900.1 291868 294120 D penicillin binding protein 2x 291868..294120 Streptococcus pneumoniae ATCC 700669 7328570 YP_002510368.1 CDS mraY NC_011900.1 294122 295102 D First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; phospho-N-acetylmuramoyl-pentapeptide- transferase 294122..295102 Streptococcus pneumoniae ATCC 700669 7328456 YP_002510369.1 CDS clpL NC_011900.1 295711 297816 D ATP-dependent protease ATP-binding subunit ClpL 295711..297816 Streptococcus pneumoniae ATCC 700669 7328132 YP_002510370.1 CDS SPN23F_03120 NC_011900.1 298252 298602 D group II intron maturase 298252..298602 Streptococcus pneumoniae ATCC 700669 7329197 YP_002510371.1 CDS luxS NC_011900.1 298669 299151 R catalyzes the hydrolysis of S-ribosylhomocysteine to homocysteine and autoinducer-2; S-ribosylhomocysteinase complement(298669..299151) Streptococcus pneumoniae ATCC 700669 7329460 YP_002510372.1 CDS SPN23F_03140 NC_011900.1 299246 300730 R hypothetical protein complement(299246..300730) Streptococcus pneumoniae ATCC 700669 7328112 YP_002510373.1 CDS dexB NC_011900.1 300883 302490 D glucan 1,6-alpha-glucosidase 300883..302490 Streptococcus pneumoniae ATCC 700669 7327515 YP_002510374.1 CDS wzg NC_011900.1 303559 305004 D capsule biosynthesis integral membrane regulatory protein Wzg 303559..305004 Streptococcus pneumoniae ATCC 700669 7327516 YP_002510375.1 CDS wzh NC_011900.1 305006 305737 D capsule biosynthesis protein-tyrosine phosphatase Wzh 305006..305737 Streptococcus pneumoniae ATCC 700669 7329442 YP_002510376.1 CDS wzd NC_011900.1 305746 306438 D capsule biosynthesis chain length determinant protein Wzd 305746..306438 Streptococcus pneumoniae ATCC 700669 7329443 YP_002510377.1 CDS wze NC_011900.1 306448 307137 D capsule biosynthesis tyrosine-protein kinase Wze 306448..307137 Streptococcus pneumoniae ATCC 700669 7329440 YP_002510378.1 CDS wchA NC_011900.1 307152 308519 D UDP-phosphate glucose phosphotransferase 307152..308519 Streptococcus pneumoniae ATCC 700669 7329441 YP_002510379.1 CDS wchF NC_011900.1 308550 309728 D rhamnosyl transferase WchF 308550..309728 Streptococcus pneumoniae ATCC 700669 7329432 YP_002510380.1 CDS wzy NC_011900.1 310028 311221 D oligosaccharide repeat unit polymerase Wzy 310028..311221 Streptococcus pneumoniae ATCC 700669 7329433 YP_002510381.1 CDS wchV NC_011900.1 311225 312196 D glycosyltransferase WchA 311225..312196 Streptococcus pneumoniae ATCC 700669 7329445 YP_002510382.1 CDS wchW NC_011900.1 312203 313435 D glycosyltransferase WchW 312203..313435 Streptococcus pneumoniae ATCC 700669 7329434 YP_002510383.1 CDS wzx NC_011900.1 313437 314822 D capsule biosynthesis repeating unit flippase Wzx 313437..314822 Streptococcus pneumoniae ATCC 700669 7329435 YP_002510384.1 CDS wchX NC_011900.1 314830 315978 D glycerol phosphotransferase WchX 314830..315978 Streptococcus pneumoniae ATCC 700669 7329444 YP_002510385.1 CDS wchY NC_011900.1 316014 317042 D glycerol-2-phosphate dehydrogenase WchY 316014..317042 Streptococcus pneumoniae ATCC 700669 7329436 YP_002510386.1 CDS wchZ NC_011900.1 317058 317762 D nucleotidyl transferase WchZ 317058..317762 Streptococcus pneumoniae ATCC 700669 7329437 YP_002510387.1 CDS wciA NC_011900.1 317777 318610 D phosphotransferase 317777..318610 Streptococcus pneumoniae ATCC 700669 7329438 YP_002510388.1 CDS rmlA NC_011900.1 318770 319639 D glucose-1-phosphate thymidyl transferase RmlA 318770..319639 Streptococcus pneumoniae ATCC 700669 7329439 YP_002510389.1 CDS rmlC NC_011900.1 319640 320233 D dTDP-4-keto-6-deoxyglucose-3,5-epimerase RmlC 319640..320233 Streptococcus pneumoniae ATCC 700669 7327459 YP_002510390.1 CDS rmlB NC_011900.1 320246 321295 D dTDP-glucose-4,6-dehydratase RmlB 320246..321295 Streptococcus pneumoniae ATCC 700669 7327461 YP_002510391.1 CDS rmlD NC_011900.1 321361 322212 D dTDP-4-dehydrorhamnose reductase RmlD 321361..322212 Streptococcus pneumoniae ATCC 700669 7327460 YP_002510392.1 CDS aliA NC_011900.1 323780 325762 D extracellular oligopeptide-binding protein 323780..325762 Streptococcus pneumoniae ATCC 700669 7327517 YP_002510393.1 CDS SPN23F_03400 NC_011900.1 326063 331366 D cell wall surface anchored protein 326063..331366 Streptococcus pneumoniae ATCC 700669 7328646 YP_002510394.1 CDS pbp1A NC_011900.1 331533 333692 R penicillin-binding protein 1A complement(331533..333692) Streptococcus pneumoniae ATCC 700669 7327518 YP_002510395.1 CDS recU NC_011900.1 333689 334285 R functions in homologous recombination, DNA repair, and chromosome segregation; binds preferentially to three- and four-stranded DNA intermediates; introduces specific nick sites in four-stranded DNA substrates; functions similarly to Escherichia coli RuvC; Holliday junction-specific endonuclease complement(333689..334285) Streptococcus pneumoniae ATCC 700669 7328453 YP_002510396.1 CDS SPN23F_03430 NC_011900.1 334352 334879 D hypothetical protein 334352..334879 Streptococcus pneumoniae ATCC 700669 7327448 YP_002510397.1 CDS SPN23F_03440 NC_011900.1 334949 335290 D DivIVA protein 334949..335290 Streptococcus pneumoniae ATCC 700669 7327519 YP_002510398.1 CDS SPN23F_03450 NC_011900.1 335776 336933 D RNA methylase family protein 335776..336933 Streptococcus pneumoniae ATCC 700669 7329461 YP_002510399.1 CDS SPN23F_03460 NC_011900.1 336946 338340 D hypothetical protein 336946..338340 Streptococcus pneumoniae ATCC 700669 7327521 YP_002510400.1 CDS gnd NC_011900.1 338416 339840 D catalyzes the formation of D-ribulose 5-phosphate from 6-phospho-D-gluconate; 6-phosphogluconate dehydrogenase 338416..339840 Streptococcus pneumoniae ATCC 700669 7327522 YP_002510401.1 CDS csrR NC_011900.1 339852 340541 D response regulator protein 339852..340541 Streptococcus pneumoniae ATCC 700669 7328617 YP_002510402.1 CDS cbpJ NC_011900.1 340640 341638 D choline binding protein J 340640..341638 Streptococcus pneumoniae ATCC 700669 7329215 YP_002510403.1 CDS SPN23F_03500 NC_011900.1 341756 342988 R Major Facilitator Superfamily protein complement(341756..342988) Streptococcus pneumoniae ATCC 700669 7329185 YP_002510404.1 CDS mvaK1 NC_011900.1 344989 345867 D mevalonate kinase 344989..345867 Streptococcus pneumoniae ATCC 700669 7327525 YP_002510405.1 CDS mvaD NC_011900.1 345849 346802 D mevalonate diphosphate decarboxylase 345849..346802 Streptococcus pneumoniae ATCC 700669 7328408 YP_002510406.1 CDS mvaK2 NC_011900.1 346789 347796 D phosphomevalonate kinase 346789..347796 Streptococcus pneumoniae ATCC 700669 7328407 YP_002510407.1 CDS fni NC_011900.1 347780 348790 D catalyzes the isomerization of isopentenyl pyrophosphate to dimethylallyl diphosphate; isopentenyl pyrophosphate isomerase 347780..348790 Streptococcus pneumoniae ATCC 700669 7328409 YP_002510408.1 CDS SPN23F_03570 NC_011900.1 348867 349565 D hypothetical protein 348867..349565 Streptococcus pneumoniae ATCC 700669 7328557 YP_002510409.1 CDS SPN23F_03580 NC_011900.1 349562 350557 D sensor histidine kinase 349562..350557 Streptococcus pneumoniae ATCC 700669 7327526 YP_002510410.1 CDS SPN23F_03590 NC_011900.1 350571 351203 D response regulator protein 350571..351203 Streptococcus pneumoniae ATCC 700669 7327527 YP_002510411.1 CDS SPN23F_03630 NC_011900.1 352123 352362 D hypothetical protein 352123..352362 Streptococcus pneumoniae ATCC 700669 7327529 YP_002510412.1 CDS cbpG NC_011900.1 352443 353264 D choline binding protein G 352443..353264 Streptococcus pneumoniae ATCC 700669 7327530 YP_002510413.1 CDS cbpF NC_011900.1 353283 354305 D choline binding protein F 353283..354305 Streptococcus pneumoniae ATCC 700669 7329184 YP_002510414.1 CDS mtlA NC_011900.1 355990 357759 D mannitol-specific phosphotransferase system (PTS), IIBC component 355990..357759 Streptococcus pneumoniae ATCC 700669 7327532 YP_002510415.1 CDS mtlR NC_011900.1 357846 359738 D transcriptional regulator 357846..359738 Streptococcus pneumoniae ATCC 700669 7328383 YP_002510416.1 CDS mtlF NC_011900.1 359740 360177 D mannitol-specific phosphotransferase system (PTS), IIA component 359740..360177 Streptococcus pneumoniae ATCC 700669 7328386 YP_002510417.1 CDS mtlD NC_011900.1 360239 361375 D mannitol-1-phosphate 5-dehydrogenase 360239..361375 Streptococcus pneumoniae ATCC 700669 7328385 YP_002510418.1 CDS SPN23F_03750 NC_011900.1 361757 361870 D hypothetical protein 361757..361870 Streptococcus pneumoniae ATCC 700669 7328384 YP_002510419.1 CDS tig NC_011900.1 362174 363457 D Tig; RopA; peptidyl-prolyl cis/trans isomerase; promotes folding of newly synthesized proteins; binds ribosomal 50S subunit; forms a homodimer; trigger factor 362174..363457 Streptococcus pneumoniae ATCC 700669 7327533 YP_002510420.1 CDS SPN23F_03770 NC_011900.1 363505 365871 R hypothetical protein complement(363505..365871) Streptococcus pneumoniae ATCC 700669 7329176 YP_002510421.1 CDS spi NC_011900.1 366150 366764 R signal peptidase I complement(366150..366764) Streptococcus pneumoniae ATCC 700669 7327534 YP_002510422.1 CDS SPN23F_03800 NC_011900.1 366776 367648 R An endonuclease that specifically degrades the RNA strand of RNA-DNA hybrids; ribonuclease HIII complement(366776..367648) Streptococcus pneumoniae ATCC 700669 7329150 YP_002510423.1 CDS SPN23F_03810 NC_011900.1 367735 368037 D hypothetical protein 367735..368037 Streptococcus pneumoniae ATCC 700669 7327535 YP_002510424.1 CDS SPN23F_03820 NC_011900.1 368034 368582 D bacteriocin production protein 368034..368582 Streptococcus pneumoniae ATCC 700669 7327536 YP_002510425.1 CDS mutS2 NC_011900.1 368686 371022 D DNA mismatch repair protein 368686..371022 Streptococcus pneumoniae ATCC 700669 7327537 YP_002510426.1 CDS SPN23F_03840 NC_011900.1 371365 372687 D sodium:alanine symporter family protein 371365..372687 Streptococcus pneumoniae ATCC 700669 7329462 YP_002510427.1 CDS SPN23F_03850 NC_011900.1 372905 373453 D decarboxylase 372905..373453 Streptococcus pneumoniae ATCC 700669 7327538 YP_002510428.1 CDS SPN23F_03860 NC_011900.1 373563 374462 D C4-dicarboxylate transporter 373563..374462 Streptococcus pneumoniae ATCC 700669 7327539 YP_002510429.1 CDS serS NC_011900.1 374487 375761 R catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; seryl-tRNA synthetase complement(374487..375761) Streptococcus pneumoniae ATCC 700669 7327540 YP_002510430.1 CDS SPN23F_03880 NC_011900.1 375975 376346 R hypothetical protein complement(375975..376346) Streptococcus pneumoniae ATCC 700669 7329143 YP_002510431.1 CDS SPN23F_03890 NC_011900.1 376349 377713 R catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP; lysine and threonine sensitive; aspartate kinase complement(376349..377713) Streptococcus pneumoniae ATCC 700669 7327541 YP_002510432.1 CDS SPN23F_03900 NC_011900.1 378038 378823 D Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; enoyl-CoA hydratase 378038..378823 Streptococcus pneumoniae ATCC 700669 7327542 YP_002510433.1 CDS SPN23F_03910 NC_011900.1 378917 379351 D MarR family transcriptional regulator 378917..379351 Streptococcus pneumoniae ATCC 700669 7327543 YP_002510434.1 CDS fabH NC_011900.1 379351 380325 D FabH; beta-ketoacyl-acyl carrier protein synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs; 3-oxoacyl-(acyl carrier protein) synthase III 379351..380325 Streptococcus pneumoniae ATCC 700669 7327544 YP_002510435.1 CDS acpP NC_011900.1 380385 380609 D carries the fatty acid chain in fatty acid biosynthesis; acyl carrier protein 380385..380609 Streptococcus pneumoniae ATCC 700669 7328548 YP_002510436.1 CDS fabK NC_011900.1 380728 381702 D enoyl-ACP reductase 380728..381702 Streptococcus pneumoniae ATCC 700669 7328631 YP_002510437.1 CDS fabD NC_011900.1 381695 382615 D malonyl CoA-acyl carrier protein transacylase 381695..382615 Streptococcus pneumoniae ATCC 700669 7328549 YP_002510438.1 CDS fabG NC_011900.1 382649 383380 D catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis; 3-ketoacyl-ACP reductase 382649..383380 Streptococcus pneumoniae ATCC 700669 7328544 YP_002510439.1 CDS fabF NC_011900.1 383402 384637 D FabF; beta-ketoacyl-ACP synthase II, KASII; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP; 3-oxoacyl-(acyl carrier protein) synthase II 383402..384637 Streptococcus pneumoniae ATCC 700669 7328547 YP_002510440.1 CDS fabE NC_011900.1 384640 385125 D composes the biotin carboxyl carrier protein subunit of the acetyl-CoA carboxylase complex, the enzyme that catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, which in turn controls the rate of fatty acid metabolism; acetyl-CoA carboxylase biotin carboxyl carrier protein subunit 384640..385125 Streptococcus pneumoniae ATCC 700669 7328546 YP_002510441.1 CDS fabZ NC_011900.1 385122 385544 D in Pseudomonas aeruginosa this enzyme is a trimer of dimers; essential for membrane formation; performs third step of type II fatty acid biosynthesis; catalyzes dehydration of (3R)-hydroxyacyl-ACP to trans-2-acyl-ACP; (3R)-hydroxymyristoyl-ACP dehydratase 385122..385544 Streptococcus pneumoniae ATCC 700669 7328545 YP_002510442.1 CDS accC NC_011900.1 385556 386923 D an AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism; acetyl-CoA carboxylase biotin carboxylase subunit 385556..386923 Streptococcus pneumoniae ATCC 700669 7328550 YP_002510443.1 CDS accD NC_011900.1 386960 387826 D catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer of AccA2D2 subunits; acetyl-CoA carboxylase subunit beta 386960..387826 Streptococcus pneumoniae ATCC 700669 7328626 YP_002510444.1 CDS accA NC_011900.1 387823 388590 D catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer composed of two alpha (AccA) and two beta (AccD) subunits; one of the two catalytic subunits that can form the acetyl CoA carboxylase enzyme together with a carrier protein; these proteins present a shorter N-terminus; acetyl-CoA carboxylase subunit alpha 387823..388590 Streptococcus pneumoniae ATCC 700669 7328627 YP_002510445.1 CDS SPN23F_04030 NC_011900.1 388853 389038 D hypothetical protein 388853..389038 Streptococcus pneumoniae ATCC 700669 7328625 YP_002510446.1 CDS SPN23F_04040 NC_011900.1 389056 389346 D hypothetical protein 389056..389346 Streptococcus pneumoniae ATCC 700669 7327545 YP_002510447.1 CDS SPN23F_04050 NC_011900.1 389401 389778 D hypothetical protein 389401..389778 Streptococcus pneumoniae ATCC 700669 7327546 YP_002510448.1 CDS nusB NC_011900.1 389825 390247 R Regulates rRNA biosynthesis by transcriptional antitermination; transcription antitermination protein NusB complement(389825..390247) Streptococcus pneumoniae ATCC 700669 7327547 YP_002510449.1 CDS SPN23F_04070 NC_011900.1 390240 390629 R hypothetical protein complement(390240..390629) Streptococcus pneumoniae ATCC 700669 7328434 YP_002510450.1 CDS efp NC_011900.1 390651 391211 R Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA; elongation factor P complement(390651..391211) Streptococcus pneumoniae ATCC 700669 7327548 YP_002510451.1 CDS gatB NC_011900.1 391340 392782 R allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; aspartyl/glutamyl-tRNA amidotransferase subunit B complement(391340..392782) Streptococcus pneumoniae ATCC 700669 7329251 YP_002510452.1 CDS gatA NC_011900.1 392782 394248 R allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; aspartyl/glutamyl-tRNA amidotransferase subunit A complement(392782..394248) Streptococcus pneumoniae ATCC 700669 7328587 YP_002510453.1 CDS gatC NC_011900.1 394248 394550 R allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; some Mycoplasma proteins contain an N-terminal fusion to an unknown domain; aspartyl/glutamyl-tRNA amidotransferase subunit C complement(394248..394550) Streptococcus pneumoniae ATCC 700669 7328586 YP_002510454.1 CDS prfC NC_011900.1 394763 396307 D stimulates the release of release factors 1 and 2 from the ribosome after hydrolysis of the ester bond in peptidyl-tRNA has occurred; GDP/GTP-binding protein; peptide chain release factor 3 394763..396307 Streptococcus pneumoniae ATCC 700669 7328588 YP_002510455.1 CDS SPN23F_04130 NC_011900.1 396576 397061 D glycosyl transferase 396576..397061 Streptococcus pneumoniae ATCC 700669 7327874 YP_002510456.1 CDS rpmB NC_011900.1 397177 397365 D required for 70S ribosome assembly; 50S ribosomal protein L28 397177..397365 Streptococcus pneumoniae ATCC 700669 7327549 YP_002510457.1 CDS SPN23F_04150 NC_011900.1 397522 397887 D hypothetical protein 397522..397887 Streptococcus pneumoniae ATCC 700669 7327493 YP_002510458.1 CDS SPN23F_04160 NC_011900.1 397890 399557 D phosphatase 397890..399557 Streptococcus pneumoniae ATCC 700669 7327550 YP_002510459.1 CDS alsS NC_011900.1 399757 401457 D catalyzes the formation of 2-acetolactate from pyruvate; also known as acetolactate synthase large subunit; acetolactate synthase catalytic subunit 399757..401457 Streptococcus pneumoniae ATCC 700669 7327551 YP_002510460.1 CDS ilvH NC_011900.1 401450 401926 D with IlvI catalyzes the formation of 2-acetolactate from pyruvate, the small subunit is required for full activity and valine sensitivity; E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates, valine sensitivity and affinity for cofactors; also known as acetolactate synthase 3 small subunit; acetolactate synthase 3 regulatory subunit 401450..401926 Streptococcus pneumoniae ATCC 700669 7328649 YP_002510461.1 CDS ilvC NC_011900.1 401992 403014 D catalyzes the formation of (R)-2,3-dihydroxy-3-methylbutanoate from (S)-2-hydroxy-2-methyl-3-oxobutanoate in valine and isoleucine biosynthesis; ketol-acid reductoisomerase 401992..403014 Streptococcus pneumoniae ATCC 700669 7328084 YP_002510462.1 CDS SPN23F_04210 NC_011900.1 403595 403951 D hypothetical protein 403595..403951 Streptococcus pneumoniae ATCC 700669 7327552 YP_002510463.1 CDS ilvA NC_011900.1 404001 405251 D catalyzes the formation of 2-oxobutanoate from L-threonine; biosynthetic; threonine dehydratase 404001..405251 Streptococcus pneumoniae ATCC 700669 7327553 YP_002510464.1 CDS SPN23F_04240 NC_011900.1 406122 406337 D hypothetical protein 406122..406337 Streptococcus pneumoniae ATCC 700669 7328081 YP_002510465.1 CDS glnQ2 NC_011900.1 406446 407186 R glutamine ABC transporter,ATP-binding protein 2 complement(406446..407186) Streptococcus pneumoniae ATCC 700669 7327554 YP_002510466.1 CDS SPN23F_04260 NC_011900.1 407186 408751 R glutamine ABC transporter, glutamine-binding protein/permease protein complement(407186..408751) Streptococcus pneumoniae ATCC 700669 7328604 YP_002510467.1 CDS SPN23F_04270 NC_011900.1 408889 410778 D hypothetical protein 408889..410778 Streptococcus pneumoniae ATCC 700669 7327555 YP_002510468.1 CDS bacA NC_011900.1 412203 413048 D BacA; phosphatase activity in Escherichia coli not kinase; involved in bacitracin resistance as bacitracin supposedly sequesters undecaprenyl disphosphate which reduces the pool of lipid carrier available to the cell; UDP pyrophosphate phosphatase 412203..413048 Streptococcus pneumoniae ATCC 700669 7327557 YP_002510469.1 CDS dinB NC_011900.1 413195 414256 R involved in translesion DNA polymerization with beta clamp of polymerase III; belongs to Y family of polymerases; does not contain proofreading function; DNA polymerase IV complement(413195..414256) Streptococcus pneumoniae ATCC 700669 7328680 YP_002510470.1 CDS pfl NC_011900.1 414604 416928 D formate acetyltransferase 414604..416928 Streptococcus pneumoniae ATCC 700669 7329231 YP_002510471.1 CDS SPN23F_04330 NC_011900.1 417295 417513 R hypothetical protein complement(417295..417513) Streptococcus pneumoniae ATCC 700669 7327834 YP_002510472.1 CDS SPN23F_04340 NC_011900.1 417840 418124 R hypothetical protein complement(417840..418124) Streptococcus pneumoniae ATCC 700669 7327558 YP_002510473.1 CDS SPN23F_04360 NC_011900.1 420048 421475 R cation transport protein complement(420048..421475) Streptococcus pneumoniae ATCC 700669 7327560 YP_002510474.1 CDS trkA NC_011900.1 421491 422840 R involved in potassium uptake; found to be peripherally associated with the inner membrane in Escherichia coli; contains an NAD-binding domain; potassium transporter peripheral membrane component complement(421491..422840) Streptococcus pneumoniae ATCC 700669 7327561 YP_002510475.1 CDS SPN23F_04380 NC_011900.1 423028 423876 D hypothetical protein 423028..423876 Streptococcus pneumoniae ATCC 700669 7327562 YP_002510476.1 CDS SPN23F_04390 NC_011900.1 423891 424439 D hypothetical protein 423891..424439 Streptococcus pneumoniae ATCC 700669 7327563 YP_002510477.1 CDS SPN23F_04400 NC_011900.1 424446 424703 D hypothetical protein 424446..424703 Streptococcus pneumoniae ATCC 700669 7327564 YP_002510478.1 CDS SPN23F_04410 NC_011900.1 424805 426487 D ABC transporter ATP-binding protein 424805..426487 Streptococcus pneumoniae ATCC 700669 7327565 YP_002510479.1 CDS SPN23F_04420 NC_011900.1 426472 427302 D transport protein 426472..427302 Streptococcus pneumoniae ATCC 700669 7327566 YP_002510480.1 CDS SPN23F_04430 NC_011900.1 427495 427998 D SpoU rRNA methylase family protein 427495..427998 Streptococcus pneumoniae ATCC 700669 7327567 YP_002510481.1 CDS SPN23F_04440 NC_011900.1 428451 429014 D hypothetical protein 428451..429014 Streptococcus pneumoniae ATCC 700669 7329463 YP_002510482.1 CDS SPN23F_04450 NC_011900.1 429004 429654 D PAP2 superfamily protein 429004..429654 Streptococcus pneumoniae ATCC 700669 7327569 YP_002510483.1 CDS SPN23F_04460 NC_011900.1 429682 430071 D hypothetical protein 429682..430071 Streptococcus pneumoniae ATCC 700669 7327570 YP_002510484.1 CDS SPN23F_04470 NC_011900.1 430076 430525 D GNAT family acetyltransferase 430076..430525 Streptococcus pneumoniae ATCC 700669 7327571 YP_002510485.1 CDS rpoE NC_011900.1 430653 431240 D participates in both the initiation and recycling phases of transcription; in the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling; DNA-directed RNA polymerase subunit delta 430653..431240 Streptococcus pneumoniae ATCC 700669 7327572 YP_002510486.1 CDS pyrG NC_011900.1 431630 433237 D CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer; CTP synthetase 431630..433237 Streptococcus pneumoniae ATCC 700669 7329107 YP_002510487.1 CDS SPN23F_04510 NC_011900.1 433796 435427 R Na+/Pi-cotransporter protein complement(433796..435427) Streptococcus pneumoniae ATCC 700669 7327434 YP_002510488.1 CDS SPN23F_04520 NC_011900.1 435720 440630 D endo-beta-N-acetylglucosaminidase 435720..440630 Streptococcus pneumoniae ATCC 700669 7327573 YP_002510489.1 CDS pgk NC_011900.1 440720 441916 D Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway; phosphoglycerate kinase 440720..441916 Streptococcus pneumoniae ATCC 700669 7327574 YP_002510490.1 CDS SPN23F_04540 NC_011900.1 442052 442579 D hypothetical protein 442052..442579 Streptococcus pneumoniae ATCC 700669 7327838 YP_002510491.1 CDS glnR NC_011900.1 442656 443012 D MerR family transcriptional regulator 442656..443012 Streptococcus pneumoniae ATCC 700669 7327575 YP_002510492.1 CDS glnA NC_011900.1 443049 444395 D glutamine synthetase 443049..444395 Streptococcus pneumoniae ATCC 700669 7328606 YP_002510493.1 CDS SPN23F_04590 NC_011900.1 445191 446471 D type I restriction-modification system S protein 445191..446471 Streptococcus pneumoniae ATCC 700669 7328602 YP_002510494.1 CDS SPN23F_04591 NC_011900.1 446419 447027 R type I restriction-modification system S protein complement(446419..447027) Streptococcus pneumoniae ATCC 700669 7327576 YP_002510495.1 CDS SPN23F_04600 NC_011900.1 447038 447835 R phage integrase/recombinase complement(447038..447835) Streptococcus pneumoniae ATCC 700669 7327577 YP_002510496.1 CDS SPN23F_04610 NC_011900.1 447892 449442 R type I restriction-modification system S protein complement(447892..449442) Streptococcus pneumoniae ATCC 700669 7327578 YP_002510497.1 CDS SPN23F_04620 NC_011900.1 449442 450905 R type I restriction-modification system M protein complement(449442..450905) Streptococcus pneumoniae ATCC 700669 7329340 YP_002510498.1 CDS SPN23F_04630 NC_011900.1 450918 453251 R type I restriction-modification system R protein complement(450918..453251) Streptococcus pneumoniae ATCC 700669 7328142 YP_002510499.1 CDS SPN23F_04640 NC_011900.1 453624 453824 D hypothetical protein 453624..453824 Streptococcus pneumoniae ATCC 700669 7328143 YP_002510500.1 CDS SPN23F_04650 NC_011900.1 453859 454368 D hypothetical protein 453859..454368 Streptococcus pneumoniae ATCC 700669 7328144 YP_002510501.1 CDS hrcA NC_011900.1 454532 455566 D Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons; heat-inducible transcription repressor 454532..455566 Streptococcus pneumoniae ATCC 700669 7328145 YP_002510502.1 CDS grpE NC_011900.1 455593 456117 D with DnaK and DnaJ acts in response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins; may act as a thermosensor; heat shock protein GrpE 455593..456117 Streptococcus pneumoniae ATCC 700669 7328076 YP_002510503.1 CDS dnaK NC_011900.1 456597 458420 D heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria; molecular chaperone DnaK 456597..458420 Streptococcus pneumoniae ATCC 700669 7328062 YP_002510504.1 CDS SPN23F_04690 NC_011900.1 458422 458778 D hypothetical protein 458422..458778 Streptococcus pneumoniae ATCC 700669 7329245 YP_002510505.1 CDS dnaJ NC_011900.1 459180 460316 D chaperone Hsp40; co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion; chaperone protein DnaJ 459180..460316 Streptococcus pneumoniae ATCC 700669 7328146 YP_002510506.1 CDS SPN23F_04710 NC_011900.1 460628 460819 R hypothetical protein complement(460628..460819) Streptococcus pneumoniae ATCC 700669 7329244 YP_002510507.1 CDS SPN23F_04720 NC_011900.1 461074 461361 R hypothetical protein complement(461074..461361) Streptococcus pneumoniae ATCC 700669 7328147 YP_002510508.1 CDS SPN23F_04730 NC_011900.1 461371 461781 R HIT-family nucleotide-binding protein complement(461371..461781) Streptococcus pneumoniae ATCC 700669 7328148 YP_002510509.1 CDS SPN23F_04740 NC_011900.1 461849 462580 D ABC transporter ATP-binding protein 461849..462580 Streptococcus pneumoniae ATCC 700669 7328149 YP_002510510.1 CDS SPN23F_04750 NC_011900.1 462577 463626 D ABC transporter 462577..463626 Streptococcus pneumoniae ATCC 700669 7328150 YP_002510511.1 CDS SPN23F_04760 NC_011900.1 463794 464123 R hypothetical protein complement(463794..464123) Streptococcus pneumoniae ATCC 700669 7328151 YP_002510512.1 CDS blpS NC_011900.1 464399 464737 D regulatory protein BlpS 464399..464737 Streptococcus pneumoniae ATCC 700669 7328152 YP_002510513.1 CDS blpR NC_011900.1 464742 465479 D response regulator protein BlpR 464742..465479 Streptococcus pneumoniae ATCC 700669 7328694 YP_002510514.1 CDS blpH NC_011900.1 465493 466833 D sensor histidine kinase BlpH 465493..466833 Streptococcus pneumoniae ATCC 700669 7328693 YP_002510515.1 CDS blpC NC_011900.1 466904 467032 R peptide pheromone BlpC (bacteriocin-like peptide) complement(466904..467032) Streptococcus pneumoniae ATCC 700669 7328687 YP_002510516.1 CDS blpB NC_011900.1 467089 468450 R ABC transporter complement(467089..468450) Streptococcus pneumoniae ATCC 700669 7328686 YP_002510517.1 CDS blpA1 NC_011900.1 468461 470014 R bacteriocin transport/processing ATP-binding protein BlpA complement(468461..470014) Streptococcus pneumoniae ATCC 700669 7328685 YP_002510518.1 CDS blpA2 NC_011900.1 470031 470618 R bacteriocin transporter C39 protease domain BlpA2 complement(470031..470618) Streptococcus pneumoniae ATCC 700669 7328683 YP_002510519.1 CDS blpI NC_011900.1 470900 471097 D bacteriocin BlpI 470900..471097 Streptococcus pneumoniae ATCC 700669 7328684 YP_002510520.1 CDS pncB NC_011900.1 471102 471263 D immunity protein PncB 471102..471263 Streptococcus pneumoniae ATCC 700669 7328688 YP_002510521.1 CDS pncC NC_011900.1 471268 471417 D hypothetical protein 471268..471417 Streptococcus pneumoniae ATCC 700669 7327856 YP_002510522.1 CDS blpJ NC_011900.1 471564 471833 D bacteriocin BlpJ 471564..471833 Streptococcus pneumoniae ATCC 700669 7327857 YP_002510523.1 CDS blpK NC_011900.1 471902 472150 D bacteriocin BlpK 471902..472150 Streptococcus pneumoniae ATCC 700669 7328689 YP_002510524.1 CDS pncK NC_011900.1 472169 472378 D immunity protein PncK 472169..472378 Streptococcus pneumoniae ATCC 700669 7328690 YP_002510525.1 CDS SPN23F_04880 NC_011900.1 472647 472766 D pncF 472647..472766 Streptococcus pneumoniae ATCC 700669 7328154 YP_002510526.1 CDS SPN23F_04890 NC_011900.1 472879 472995 D hypothetical protein 472879..472995 Streptococcus pneumoniae ATCC 700669 7328155 YP_002510527.1 CDS pncG NC_011900.1 473063 473224 D immunity protein 473063..473224 Streptococcus pneumoniae ATCC 700669 7328156 YP_002510528.1 CDS blpL NC_011900.1 473234 473605 D hypothetical protein 473234..473605 Streptococcus pneumoniae ATCC 700669 7327858 YP_002510529.1 CDS pncM NC_011900.1 473783 473962 D immunity protein PncM 473783..473962 Streptococcus pneumoniae ATCC 700669 7328691 YP_002510530.1 CDS SPN23F_04920 NC_011900.1 473994 474134 D hypothetical protein 473994..474134 Streptococcus pneumoniae ATCC 700669 7327860 YP_002510531.1 CDS blpX NC_011900.1 474234 474617 D immunity protein BlpX 474234..474617 Streptococcus pneumoniae ATCC 700669 7328157 YP_002510532.1 CDS blpY NC_011900.1 474669 475358 D bacteeriocin ABC transporter transmembrane domain BlpY (CAAX protease) 474669..475358 Streptococcus pneumoniae ATCC 700669 7328695 YP_002510533.1 CDS blpZ NC_011900.1 475400 475633 D immunity protein BlpZ 475400..475633 Streptococcus pneumoniae ATCC 700669 7328696 YP_002510534.1 CDS pncP NC_011900.1 475784 476395 D ABC transporter ATP-binding protein 475784..476395 Streptococcus pneumoniae ATCC 700669 7328697 YP_002510535.1 CDS SPN23F_04960 NC_011900.1 476556 477350 D phosphotransferase 476556..477350 Streptococcus pneumoniae ATCC 700669 7327861 YP_002510536.1 CDS trmB NC_011900.1 477347 477982 D tRNA (guanine-N(7)-)-methyltransferase; catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA by transferring the methyl residue from S-adenosyl-L-methionine; tRNA (guanine-N(7)-)-methyltransferase 477347..477982 Streptococcus pneumoniae ATCC 700669 7328158 YP_002510537.1 CDS SPN23F_04980 NC_011900.1 478108 478587 D in Streptococcus pneumoniae this gene was found to be essential; structure determination of the Streptococcus protein shows that it is similar to a number of other proteins; hypothetical protein 478108..478587 Streptococcus pneumoniae ATCC 700669 7328159 YP_002510538.1 CDS nusA NC_011900.1 478631 479767 D modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination; transcription elongation factor NusA 478631..479767 Streptococcus pneumoniae ATCC 700669 7328160 YP_002510539.1 CDS SPN23F_05000 NC_011900.1 479789 480082 D hypothetical protein 479789..480082 Streptococcus pneumoniae ATCC 700669 7328433 YP_002510540.1 CDS SPN23F_05010 NC_011900.1 480075 480374 D hypothetical protein 480075..480374 Streptococcus pneumoniae ATCC 700669 7328161 YP_002510541.1 CDS infB NC_011900.1 480391 483183 D Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; translation initiation factor IF-2 480391..483183 Streptococcus pneumoniae ATCC 700669 7328162 YP_002510542.1 CDS rbfA NC_011900.1 483434 483784 D associates with free 30S ribosomal subunits; essential for efficient processing of 16S rRNA; in Escherichia coli rbfA is induced by cold shock; ribosome-binding factor A 483434..483784 Streptococcus pneumoniae ATCC 700669 7328086 YP_002510543.1 CDS SPN23F_05040 NC_011900.1 484063 484842 D hypothetical protein 484063..484842 Streptococcus pneumoniae ATCC 700669 7327441 YP_002510544.1 CDS SPN23F_05050 NC_011900.1 484844 485026 D hypothetical protein 484844..485026 Streptococcus pneumoniae ATCC 700669 7328163 YP_002510545.1 CDS SPN23F_05060 NC_011900.1 485304 485546 R hypothetical protein complement(485304..485546) Streptococcus pneumoniae ATCC 700669 7328164 YP_002510546.1 CDS SPN23F_05070 NC_011900.1 485577 485810 D hypothetical protein 485577..485810 Streptococcus pneumoniae ATCC 700669 7328165 YP_002510547.1 CDS SPN23F_05080 NC_011900.1 485810 487144 D hypothetical protein 485810..487144 Streptococcus pneumoniae ATCC 700669 7328166 YP_002510548.1 CDS SPN23F_05090 NC_011900.1 487154 487408 D hypothetical protein 487154..487408 Streptococcus pneumoniae ATCC 700669 7328167 YP_002510549.1 CDS SPN23F_05100 NC_011900.1 487504 487899 D hypothetical protein 487504..487899 Streptococcus pneumoniae ATCC 700669 7328168 YP_002510550.1 CDS SPN23F_05110 NC_011900.1 488312 488761 D hypothetical protein 488312..488761 Streptococcus pneumoniae ATCC 700669 7328169 YP_002510551.1 CDS SPN23F_05120 NC_011900.1 488748 489305 D acetyltransferase 488748..489305 Streptococcus pneumoniae ATCC 700669 7328170 YP_002510552.1 CDS SPN23F_05130 NC_011900.1 489307 490269 D hypothetical protein 489307..490269 Streptococcus pneumoniae ATCC 700669 7328171 YP_002510553.1 CDS valS NC_011900.1 490281 492932 D valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain; valyl-tRNA synthetase 490281..492932 Streptococcus pneumoniae ATCC 700669 7328172 YP_002510554.1 CDS SPN23F_05150 NC_011900.1 493002 493757 D hypothetical protein 493002..493757 Streptococcus pneumoniae ATCC 700669 7329426 YP_002510555.1 CDS SPN23F_05151 NC_011900.1 494038 494841 D cell filamentation protein fic-related protein 494038..494841 Streptococcus pneumoniae ATCC 700669 7328173 YP_002510556.1 CDS SPN23F_05190 NC_011900.1 496704 499262 D type III restriction endonuclease 496704..499262 Streptococcus pneumoniae ATCC 700669 7328176 YP_002510557.1 CDS SPN23F_05200 NC_011900.1 499562 500401 D transcription antiterminator 499562..500401 Streptococcus pneumoniae ATCC 700669 7328177 YP_002510558.1 CDS SPN23F_05210 NC_011900.1 500419 502257 D beta-glucoside-specific phosphotransferase system (PTS), IIABC component 500419..502257 Streptococcus pneumoniae ATCC 700669 7328178 YP_002510559.1 CDS SPN23F_05220 NC_011900.1 502270 503685 D 6-phospho-beta-glucosidase 502270..503685 Streptococcus pneumoniae ATCC 700669 7328179 YP_002510560.1 CDS pheS NC_011900.1 504196 505323 D catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily; phenylalanyl-tRNA synthetase subunit alpha 504196..505323 Streptococcus pneumoniae ATCC 700669 7328180 YP_002510561.1 CDS SPN23F_05240 NC_011900.1 505323 505832 D GNAT family acetyltransferase 505323..505832 Streptococcus pneumoniae ATCC 700669 7327842 YP_002510562.1 CDS pheT NC_011900.1 505909 508311 D catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily; phenylalanyl-tRNA synthetase subunit beta 505909..508311 Streptococcus pneumoniae ATCC 700669 7328181 YP_002510563.1 CDS SPN23F_05260 NC_011900.1 508379 509380 R integral membrane protein complement(508379..509380) Streptococcus pneumoniae ATCC 700669 7327843 YP_002510564.1 CDS SPN23F_05280 NC_011900.1 510108 510374 D hypothetical protein 510108..510374 Streptococcus pneumoniae ATCC 700669 7328183 YP_002510565.1 CDS metE NC_011900.1 510635 512884 D catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine to form methionine; 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase 510635..512884 Streptococcus pneumoniae ATCC 700669 7328184 YP_002510566.1 CDS metF NC_011900.1 512948 513814 D 5,10-methylenetetrahydrofolate reductase 512948..513814 Streptococcus pneumoniae ATCC 700669 7328126 YP_002510567.1 CDS pnpA NC_011900.1 514499 516712 D polynucleotide phosphorylase/polyadenylase 514499..516712 Streptococcus pneumoniae ATCC 700669 7328127 YP_002510568.1 CDS cysE NC_011900.1 516728 517345 D serine acetyltransferase 516728..517345 Streptococcus pneumoniae ATCC 700669 7327862 YP_002510569.1 CDS SPN23F_05330 NC_011900.1 517357 518241 D GNAT family acetyltransferase 517357..518241 Streptococcus pneumoniae ATCC 700669 7329218 YP_002510570.1 CDS cysS NC_011900.1 518328 519671 D catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA; cysteinyl-tRNA synthetase 518328..519671 Streptococcus pneumoniae ATCC 700669 7328185 YP_002510571.1 CDS SPN23F_05350 NC_011900.1 519664 520050 D ribomuclease 519664..520050 Streptococcus pneumoniae ATCC 700669 7329220 YP_002510572.1 CDS SPN23F_05360 NC_011900.1 520054 520938 D leucine-rich protein 520054..520938 Streptococcus pneumoniae ATCC 700669 7328186 YP_002510573.1 CDS SPN23F_05370 NC_011900.1 520985 522241 R IS1167A transposase complement(520985..522241) Streptococcus pneumoniae ATCC 700669 7328187 YP_002510574.1 CDS SPN23F_05380 NC_011900.1 522604 523203 D hypothetical protein 522604..523203 Streptococcus pneumoniae ATCC 700669 7328188 YP_002510575.1 CDS SPN23F_05400 NC_011900.1 523873 525150 D ABC transporter permease 523873..525150 Streptococcus pneumoniae ATCC 700669 7329464 YP_002510576.1 CDS SPN23F_05410 NC_011900.1 525163 525810 D ABC transporter ATP-binding protein 525163..525810 Streptococcus pneumoniae ATCC 700669 7328191 YP_002510577.1 CDS SPN23F_05420 NC_011900.1 525862 527241 D ABC transporter permease 525862..527241 Streptococcus pneumoniae ATCC 700669 7328192 YP_002510578.1 CDS SPN23F_05430 NC_011900.1 527553 528209 D two-component system, response regulator 527553..528209 Streptococcus pneumoniae ATCC 700669 7328193 YP_002510579.1 CDS SPN23F_05440 NC_011900.1 528206 529534 D two-component system, sensor histidine kinase 528206..529534 Streptococcus pneumoniae ATCC 700669 7328194 YP_002510580.1 CDS fba NC_011900.1 529675 530556 D catalyzes the formation of glycerone phosphate and glyceraldehyde 3-phosphate from fructose 1,6, bisphosphate; fructose-bisphosphate aldolase 529675..530556 Streptococcus pneumoniae ATCC 700669 7328195 YP_002510581.1 CDS SPN23F_05460 NC_011900.1 530877 532067 R flavocytochrome complement(530877..532067) Streptococcus pneumoniae ATCC 700669 7328551 YP_002510582.1 CDS SPN23F_05470 NC_011900.1 532362 533021 R amino acid ABC transporter permease complement(532362..533021) Streptococcus pneumoniae ATCC 700669 7328196 YP_002510583.1 CDS SPN23F_05480 NC_011900.1 533031 533708 R amino acid ABC transporter permease complement(533031..533708) Streptococcus pneumoniae ATCC 700669 7328197 YP_002510584.1 CDS SPN23F_05490 NC_011900.1 533721 534485 R glutamine-binding protein precursor complement(533721..534485) Streptococcus pneumoniae ATCC 700669 7328198 YP_002510585.1 CDS SPN23F_05500 NC_011900.1 534525 535283 R glutamine transporter, ATP-binding protein complement(534525..535283) Streptococcus pneumoniae ATCC 700669 7328199 YP_002510586.1 CDS SPN23F_05510 NC_011900.1 535560 537782 D phosphoesterase 535560..537782 Streptococcus pneumoniae ATCC 700669 7328200 YP_002510587.1 CDS SPN23F_05520 NC_011900.1 537957 539618 D metallo-beta-lactamase superfamily protein 537957..539618 Streptococcus pneumoniae ATCC 700669 7328201 YP_002510588.1 CDS SPN23F_05530 NC_011900.1 539687 540466 D esterase 539687..540466 Streptococcus pneumoniae ATCC 700669 7328202 YP_002510589.1 CDS murM NC_011900.1 540578 541798 D peptidoglycan pentaglycine interpeptide biosynthesis protein 540578..541798 Streptococcus pneumoniae ATCC 700669 7328203 YP_002510590.1 CDS murN NC_011900.1 541803 543035 D peptidoglycan branched peptide synthesis protein 541803..543035 Streptococcus pneumoniae ATCC 700669 7328398 YP_002510591.1 CDS SPN23F_05560 NC_011900.1 543114 543815 D protease 543114..543815 Streptococcus pneumoniae ATCC 700669 7328399 YP_002510592.1 CDS uvrC NC_011900.1 543855 545702 D The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision; excinuclease ABC subunit C 543855..545702 Streptococcus pneumoniae ATCC 700669 7328204 YP_002510593.1 CDS SPN23F_05580 NC_011900.1 545752 546189 D hypothetical protein 545752..546189 Streptococcus pneumoniae ATCC 700669 7329425 YP_002510594.1 CDS SPN23F_05590 NC_011900.1 546190 546525 D hypothetical protein 546190..546525 Streptococcus pneumoniae ATCC 700669 7328205 YP_002510595.1 CDS SPN23F_05600 NC_011900.1 546709 547509 R extracellular solute-binding protein complement(546709..547509) Streptococcus pneumoniae ATCC 700669 7328206 YP_002510596.1 CDS SPN23F_05610 NC_011900.1 547680 548285 D nitroreductase family protein 547680..548285 Streptococcus pneumoniae ATCC 700669 7328207 YP_002510597.1 CDS pepV NC_011900.1 548298 549698 D divalent metal ion-dependent extracellular dipeptidase; able to hydrolyze a broad range of dipeptides but no tri-, tetra-, or larger oligopeptides; differences in the amino acid specificity of the cleavage site varies between species; similar to succinyl-diaminopimelate desuccinylases; dipeptidase PepV 548298..549698 Streptococcus pneumoniae ATCC 700669 7328208 YP_002510598.1 CDS SPN23F_05630 NC_011900.1 549752 550330 D uracil DNA glycosylase superfamily protein 549752..550330 Streptococcus pneumoniae ATCC 700669 7327831 YP_002510599.1 CDS SPN23F_05640 NC_011900.1 550490 550642 D hypothetical protein 550490..550642 Streptococcus pneumoniae ATCC 700669 7328209 YP_002510600.1 CDS SPN23F_05641 NC_011900.1 550643 550777 D hypothetical protein 550643..550777 Streptococcus pneumoniae ATCC 700669 7328210 YP_002510601.1 CDS brnQ NC_011900.1 550948 552273 D branched-chain amino acid transport system carrier protein 550948..552273 Streptococcus pneumoniae ATCC 700669 7328211 YP_002510602.1 CDS SPN23F_05660 NC_011900.1 552371 553408 D M42 glutamyl aminopeptidase 552371..553408 Streptococcus pneumoniae ATCC 700669 7328698 YP_002510603.1 CDS SPN23F_05670 NC_011900.1 553410 553871 D HIT family protein 553410..553871 Streptococcus pneumoniae ATCC 700669 7328212 YP_002510604.1 CDS SPN23F_05680 NC_011900.1 553889 554605 D carboxypeptidase 553889..554605 Streptococcus pneumoniae ATCC 700669 7328213 YP_002510605.1 CDS rplK NC_011900.1 554728 555153 D binds directly to 23S ribosomal RNA; 50S ribosomal protein L11 554728..555153 Streptococcus pneumoniae ATCC 700669 7328214 YP_002510606.1 CDS rplA NC_011900.1 555361 556050 D in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA; 50S ribosomal protein L1 555361..556050 Streptococcus pneumoniae ATCC 700669 7327478 YP_002510607.1 CDS SPN23F_05720 NC_011900.1 556946 557164 D hypothetical protein 556946..557164 Streptococcus pneumoniae ATCC 700669 7328215 YP_002510608.1 CDS SPN23F_05730 NC_011900.1 557563 557808 D hypothetical protein 557563..557808 Streptococcus pneumoniae ATCC 700669 7328216 YP_002510609.1 CDS SPN23F_05740 NC_011900.1 558209 559201 D ABC transporter ATP-binding protein 558209..559201 Streptococcus pneumoniae ATCC 700669 7328217 YP_002510610.1 CDS SPN23F_05750 NC_011900.1 559203 560021 D hypothetical protein 559203..560021 Streptococcus pneumoniae ATCC 700669 7328218 YP_002510611.1 CDS SPN23F_05760 NC_011900.1 560023 560808 D hypothetical protein 560023..560808 Streptococcus pneumoniae ATCC 700669 7328219 YP_002510612.1 CDS SPN23F_05770 NC_011900.1 560906 561124 D hypothetical protein 560906..561124 Streptococcus pneumoniae ATCC 700669 7328220 YP_002510613.1 CDS SPN23F_05780 NC_011900.1 561109 561270 D hypothetical protein 561109..561270 Streptococcus pneumoniae ATCC 700669 7328221 YP_002510614.1 CDS SPN23F_05790 NC_011900.1 561994 568428 D surface-anchored serine protease 561994..568428 Streptococcus pneumoniae ATCC 700669 7328222 YP_002510615.1 CDS SPN23F_05800 NC_011900.1 569060 569536 D sugar phosphotransferase system (PTS),IIA component 569060..569536 Streptococcus pneumoniae ATCC 700669 7328223 YP_002510616.1 CDS SPN23F_05810 NC_011900.1 569574 569879 D sugar phosphotransferase system (PTS), IIB component 569574..569879 Streptococcus pneumoniae ATCC 700669 7328224 YP_002510617.1 CDS SPN23F_05820 NC_011900.1 569927 571402 D sugar phosphotransferase system (PTS),galactitol-specific family, IIC component 569927..571402 Streptococcus pneumoniae ATCC 700669 7328225 YP_002510618.1 CDS bgaA NC_011900.1 571752 578453 D surface anchored beta-galactosidase 571752..578453 Streptococcus pneumoniae ATCC 700669 7328226 YP_002510619.1 CDS SPN23F_05840 NC_011900.1 578763 579305 R hypothetical protein complement(578763..579305) Streptococcus pneumoniae ATCC 700669 7328681 YP_002510620.1 CDS SPN23F_05850 NC_011900.1 579305 579550 R hypothetical protein complement(579305..579550) Streptococcus pneumoniae ATCC 700669 7328227 YP_002510621.1 CDS SPN23F_05860 NC_011900.1 579761 580120 R hypothetical protein complement(579761..580120) Streptococcus pneumoniae ATCC 700669 7328228 YP_002510622.1 CDS SPN23F_05890 NC_011900.1 581152 581709 D rRNA methylase 581152..581709 Streptococcus pneumoniae ATCC 700669 7328230 YP_002510623.1 CDS SPN23F_05900 NC_011900.1 581702 581956 D hypothetical protein 581702..581956 Streptococcus pneumoniae ATCC 700669 7328231 YP_002510624.1 CDS SPN23F_05910 NC_011900.1 581968 584022 D sodium hydrogen exchange transporter 581968..584022 Streptococcus pneumoniae ATCC 700669 7328232 YP_002510625.1 CDS SPN23F_05920 NC_011900.1 584201 585061 D ribonuclease BN-like family protein 584201..585061 Streptococcus pneumoniae ATCC 700669 7328233 YP_002510626.1 CDS ccdA NC_011900.1 585272 585982 D cytochrome c-type biogenesis protein CcdA 585272..585982 Streptococcus pneumoniae ATCC 700669 7328234 YP_002510627.1 CDS SPN23F_05940 NC_011900.1 586002 586568 D redoxin 586002..586568 Streptococcus pneumoniae ATCC 700669 7329187 YP_002510628.1 CDS msrAB NC_011900.1 586579 587691 D peptide methionine sulfoxide reductase 586579..587691 Streptococcus pneumoniae ATCC 700669 7328235 YP_002510629.1 CDS SPN23F_05960 NC_011900.1 588049 588786 D response regulator protein 588049..588786 Streptococcus pneumoniae ATCC 700669 7328140 YP_002510630.1 CDS SPN23F_05970 NC_011900.1 588783 590474 D sensor histidine kinase 588783..590474 Streptococcus pneumoniae ATCC 700669 7328236 YP_002510631.1 CDS SPN23F_05980 NC_011900.1 590590 591153 D hypothetical protein 590590..591153 Streptococcus pneumoniae ATCC 700669 7328237 YP_002510632.1 CDS zmpB NC_011900.1 591175 596844 D zinc metalloproteinase ZmpB 591175..596844 Streptococcus pneumoniae ATCC 700669 7328238 YP_002510633.1 CDS pabB NC_011900.1 596905 598626 D chorismate binding enzyme 596905..598626 Streptococcus pneumoniae ATCC 700669 7329452 YP_002510634.1 CDS SPN23F_06010 NC_011900.1 598746 600272 D pneumococcal surface protein 598746..600272 Streptococcus pneumoniae ATCC 700669 7328450 YP_002510635.1 CDS SPN23F_06030 NC_011900.1 600359 601222 D hypothetical protein 600359..601222 Streptococcus pneumoniae ATCC 700669 7328239 YP_002510636.1 CDS glkA NC_011900.1 601413 602372 D glucokinase 601413..602372 Streptococcus pneumoniae ATCC 700669 7328240 YP_002510637.1 CDS thyA NC_011900.1 602469 603308 D ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived; thymidylate synthase 602469..603308 Streptococcus pneumoniae ATCC 700669 7328600 YP_002510638.1 CDS SPN23F_06060 NC_011900.1 603356 603526 R hypothetical protein complement(603356..603526) Streptococcus pneumoniae ATCC 700669 7329175 YP_002510639.1 CDS miaA NC_011900.1 603647 604531 D IPP transferase; isopentenyltransferase; involved in tRNA modification; in Escherichia coli this enzyme catalyzes the addition of a delta2-isopentenyl group from dimethylallyl diphosphate to the N6-nitrogen of adenosine adjacent to the anticodon of tRNA species that read codons starting with uracil; further tRNA modifications may occur; mutations in miaA result in defects in translation efficiency and fidelity; tRNA delta(2)-isopentenylpyrophosphate transferase 603647..604531 Streptococcus pneumoniae ATCC 700669 7328241 YP_002510640.1 CDS SPN23F_06080 NC_011900.1 604524 605762 D GTPase 604524..605762 Streptococcus pneumoniae ATCC 700669 7328130 YP_002510641.1 CDS SPN23F_06090 NC_011900.1 605755 606378 D hypothetical protein 605755..606378 Streptococcus pneumoniae ATCC 700669 7328242 YP_002510642.1 CDS rnz NC_011900.1 606393 607322 D member of metallo-beta-lactamase family; the purified enzyme from Escherichia coli forms dimeric zinc phosphodiesterase; in Bacillus subtilis this protein is a 3'-tRNA processing endoribonuclease and is essential while in Escherichia coli it is not; associates with two zinc ions; ribonuclease Z 606393..607322 Streptococcus pneumoniae ATCC 700669 7328243 YP_002510643.1 CDS SPN23F_06110 NC_011900.1 607343 608098 D short chain dehydrogenase 607343..608098 Streptococcus pneumoniae ATCC 700669 7327467 YP_002510644.1 CDS SPN23F_06120 NC_011900.1 608152 609120 R LysR family transcriptional regulator complement(608152..609120) Streptococcus pneumoniae ATCC 700669 7328244 YP_002510645.1 CDS SPN23F_06130 NC_011900.1 609124 609393 D hypothetical protein 609124..609393 Streptococcus pneumoniae ATCC 700669 7328245 YP_002510646.1 CDS SPN23F_06140 NC_011900.1 609393 609773 D hypothetical protein 609393..609773 Streptococcus pneumoniae ATCC 700669 7328246 YP_002510647.1 CDS SPN23F_06150 NC_011900.1 610129 610854 R ribosomal small subunit pseudouridine synthase A complement(610129..610854) Streptococcus pneumoniae ATCC 700669 7328247 YP_002510648.1 CDS SPN23F_06160 NC_011900.1 611016 612857 D BipA family GTPase 611016..612857 Streptococcus pneumoniae ATCC 700669 7328248 YP_002510649.1 CDS SPN23F_06170 NC_011900.1 612877 613131 D hypothetical protein 612877..613131 Streptococcus pneumoniae ATCC 700669 7328249 YP_002510650.1 CDS SPN23F_06180 NC_011900.1 613679 613795 D hypothetical protein 613679..613795 Streptococcus pneumoniae ATCC 700669 7328250 YP_002510651.1 CDS SPN23F_06190 NC_011900.1 613878 614501 D hypothetical protein 613878..614501 Streptococcus pneumoniae ATCC 700669 7328251 YP_002510652.1 CDS SPN23F_06200 NC_011900.1 614724 615899 D hypothetical protein 614724..615899 Streptococcus pneumoniae ATCC 700669 7328252 YP_002510653.1 CDS SPN23F_06210 NC_011900.1 615901 616542 D ABC transporter ATP-binding protein 615901..616542 Streptococcus pneumoniae ATCC 700669 7328253 YP_002510654.1 CDS murD NC_011900.1 616646 617998 D UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase 616646..617998 Streptococcus pneumoniae ATCC 700669 7328254 YP_002510655.1 CDS murG NC_011900.1 618002 619060 D UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; involved in cell wall formation; inner membrane-associated; last step of peptidoglycan synthesis; UDP diphospho-muramoyl pentapeptide beta-N acetylglucosaminyl transferase 618002..619060 Streptococcus pneumoniae ATCC 700669 7328394 YP_002510656.1 CDS divIB NC_011900.1 619070 620269 D cell division protein DivIB/FtsQ 619070..620269 Streptococcus pneumoniae ATCC 700669 7328397 YP_002510657.1 CDS pyrF NC_011900.1 620502 621203 D type 1 subfamily; involved in last step of pyrimidine biosynthesis; converts orotidine 5'-phosphate to UMP and carbon dioxide; OMP decarboxylase; OMPDCase; OMPdecase; orotidine 5'-phosphate decarboxylase 620502..621203 Streptococcus pneumoniae ATCC 700669 7329232 YP_002510658.1 CDS pyrE NC_011900.1 621237 621869 D involved in fifth step of pyrimidine biosynthesis; converts orotidine 5'-phosphate and diphosphate to orotate and 5-phospho-alpha-D-ribose 1-diphosphate; orotate phosphoribosyltransferase 621237..621869 Streptococcus pneumoniae ATCC 700669 7327433 YP_002510659.1 CDS SPN23F_06270 NC_011900.1 622102 622452 D hypothetical protein 622102..622452 Streptococcus pneumoniae ATCC 700669 7327432 YP_002510660.1 CDS SPN23F_06280 NC_011900.1 622548 623312 D hypothetical protein 622548..623312 Streptococcus pneumoniae ATCC 700669 7328255 YP_002510661.1 CDS SPN23F_06290 NC_011900.1 623312 624064 D hypothetical protein 623312..624064 Streptococcus pneumoniae ATCC 700669 7328256 YP_002510662.1 CDS SPN23F_06300 NC_011900.1 624068 624772 D hypothetical protein 624068..624772 Streptococcus pneumoniae ATCC 700669 7328257 YP_002510663.1 CDS ccmA NC_011900.1 624769 625416 D heme exporter protein A (cytochrome C-type biogenesis protein) 624769..625416 Streptococcus pneumoniae ATCC 700669 7328258 YP_002510664.1 CDS SPN23F_06340 NC_011900.1 626369 627127 R amino acid ABC transporter ATP-binding protein complement(626369..627127) Streptococcus pneumoniae ATCC 700669 7328260 YP_002510665.1 CDS SPN23F_06350 NC_011900.1 627128 627805 R amino acid ABC transporter permease complement(627128..627805) Streptococcus pneumoniae ATCC 700669 7328261 YP_002510666.1 CDS SPN23F_06360 NC_011900.1 627765 628385 R amino acid ABC transporter permease complement(627765..628385) Streptococcus pneumoniae ATCC 700669 7328262 YP_002510667.1 CDS SPN23F_06370 NC_011900.1 628659 628805 D L-lactate oxidase-related protein 628659..628805 Streptococcus pneumoniae ATCC 700669 7328263 YP_002510668.1 CDS lysS NC_011900.1 628933 630423 D class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1; lysyl-tRNA synthetase 628933..630423 Streptococcus pneumoniae ATCC 700669 7328264 YP_002510669.1 CDS lctO NC_011900.1 631049 632185 D L-lactate oxidase 631049..632185 Streptococcus pneumoniae ATCC 700669 7328113 YP_002510670.1 CDS SPN23F_06400 NC_011900.1 632742 633410 D coenzyme 632742..633410 Streptococcus pneumoniae ATCC 700669 7329466 YP_002510671.1 CDS thiM NC_011900.1 633736 634518 D catalyzes the formation of 4-methyl-5-(2-phosphoethyl)-thiazole and ADP from 4-methyl-5-(2-hydroxyethyl)-thiazole and ATP; hydroxyethylthiazole kinase 633736..634518 Streptococcus pneumoniae ATCC 700669 7328265 YP_002510672.1 CDS thiE NC_011900.1 634520 635149 D thiamine-phosphate pyrophosphorylase 634520..635149 Streptococcus pneumoniae ATCC 700669 7329171 YP_002510673.1 CDS SPN23F_06440 NC_011900.1 635708 636268 D hypothetical protein 635708..636268 Streptococcus pneumoniae ATCC 700669 7329467 YP_002510674.1 CDS SPN23F_06450 NC_011900.1 636269 637654 D ABC transporter ATP-binding protein 636269..637654 Streptococcus pneumoniae ATCC 700669 7328266 YP_002510675.1 CDS SPN23F_06460 NC_011900.1 637656 638306 D hypothetical protein 637656..638306 Streptococcus pneumoniae ATCC 700669 7328267 YP_002510676.1 CDS SPN23F_06470 NC_011900.1 638317 639009 D coenzyme 638317..639009 Streptococcus pneumoniae ATCC 700669 7328268 YP_002510677.1 CDS SPN23F_06480 NC_011900.1 639014 639538 D hypothetical protein 639014..639538 Streptococcus pneumoniae ATCC 700669 7328269 YP_002510678.1 CDS SPN23F_06490 NC_011900.1 639538 640341 D hydroxyethylthiazole kinase 639538..640341 Streptococcus pneumoniae ATCC 700669 7328270 YP_002510679.1 CDS thiE NC_011900.1 640334 640966 D Condenses 4-methyl-5-(beta-hydroxyethyl)-thiazole monophosphate and 4-amino-5-hydroxymethyl pyrimidine pyrophosphate to form thiamine monophosphate; thiamine-phosphate pyrophosphorylase 640334..640966 Streptococcus pneumoniae ATCC 700669 7328271 YP_002510680.1 CDS thiD NC_011900.1 641176 641967 R catalyzes the formation of 4-amino-2-methyl-5-diphosphomethylpyrimidine; phosphomethylpyrimidine kinase complement(641176..641967) Streptococcus pneumoniae ATCC 700669 7329169 YP_002510681.1 CDS SPN23F_06520 NC_011900.1 642333 642728 D Homologues control the copper transport or penicillin resistance; regulator 642333..642728 Streptococcus pneumoniae ATCC 700669 7329468 YP_002510682.1 CDS SPN23F_06530 NC_011900.1 642739 643110 D hypothetical protein 642739..643110 Streptococcus pneumoniae ATCC 700669 7328272 YP_002510683.1 CDS SPN23F_06540 NC_011900.1 643120 645363 D metal transporting P-type ATPase 643120..645363 Streptococcus pneumoniae ATCC 700669 7328273 YP_002510684.1 CDS spxB NC_011900.1 645570 647345 D pyruvate oxidase 645570..647345 Streptococcus pneumoniae ATCC 700669 7328274 YP_002510685.1 CDS SPN23F_06560 NC_011900.1 647456 647803 D glyoxalase family protein 647456..647803 Streptococcus pneumoniae ATCC 700669 7329152 YP_002510686.1 CDS SPN23F_06590 NC_011900.1 649241 649522 D glycosyl hydrolase 649241..649522 Streptococcus pneumoniae ATCC 700669 7328277 YP_002510687.1 CDS pmi NC_011900.1 649654 650598 D mannose-6-phosphate isomerase 649654..650598 Streptococcus pneumoniae ATCC 700669 7328278 YP_002510688.1 CDS SPN23F_06630 NC_011900.1 652270 652932 D MerR-family transcriptional regulator 652270..652932 Streptococcus pneumoniae ATCC 700669 7328279 YP_002510689.1 CDS SPN23F_06640 NC_011900.1 652961 653377 R MutT/NUDIX family protein complement(652961..653377) Streptococcus pneumoniae ATCC 700669 7328280 YP_002510690.1 CDS SPN23F_06650 NC_011900.1 653436 654611 R hypothetical protein complement(653436..654611) Streptococcus pneumoniae ATCC 700669 7328281 YP_002510691.1 CDS SPN23F_06660 NC_011900.1 654670 655515 R fatty-acid binding protein complement(654670..655515) Streptococcus pneumoniae ATCC 700669 7328282 YP_002510692.1 CDS SPN23F_06670 NC_011900.1 655640 656197 D TetR family transcriptional regulator 655640..656197 Streptococcus pneumoniae ATCC 700669 7328283 YP_002510693.1 CDS SPN23F_06680 NC_011900.1 656216 656683 D cytidine and deoxycytidylate deaminase 656216..656683 Streptococcus pneumoniae ATCC 700669 7328284 YP_002510694.1 CDS upp NC_011900.1 656751 657401 D Catalyzes the formation of uracil and 5-phospho-alpha-D-ribosy 1-diphosphate from UMP and diphosphate; uracil phosphoribosyltransferase 656751..657401 Streptococcus pneumoniae ATCC 700669 7328285 YP_002510695.1 CDS clpP NC_011900.1 657575 658165 D hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates; ATP-dependent Clp protease proteolytic subunit 657575..658165 Streptococcus pneumoniae ATCC 700669 7329421 YP_002510696.1 CDS SPN23F_06710 NC_011900.1 658244 658492 D hypothetical protein 658244..658492 Streptococcus pneumoniae ATCC 700669 7329198 YP_002510697.1 CDS SPN23F_06720 NC_011900.1 658594 659754 D branched-chain amino acid ABC transporter, amino acid-binding protein 658594..659754 Streptococcus pneumoniae ATCC 700669 7328286 YP_002510698.1 CDS SPN23F_06730 NC_011900.1 660022 660891 D branched-chain amino acid transport system permease protein 660022..660891 Streptococcus pneumoniae ATCC 700669 7328287 YP_002510699.1 CDS SPN23F_06740 NC_011900.1 660895 661851 D branched-chain amino acid transport system permease protein 660895..661851 Streptococcus pneumoniae ATCC 700669 7328288 YP_002510700.1 CDS SPN23F_06750 NC_011900.1 661851 662615 D branched-chain amino acid transport ATP-binding protein 661851..662615 Streptococcus pneumoniae ATCC 700669 7328289 YP_002510701.1 CDS SPN23F_06760 NC_011900.1 662615 663325 D branched-chain amino acid transport ATP-binding protein 662615..663325 Streptococcus pneumoniae ATCC 700669 7328290 YP_002510702.1 CDS SPN23F_06770 NC_011900.1 663633 664289 D hypothetical protein 663633..664289 Streptococcus pneumoniae ATCC 700669 7328291 YP_002510703.1 CDS prfB NC_011900.1 664515 665492 D recognizes the termination signals UGA and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF2; in some organisms control of PrfB protein levels is maintained through a +1 ribosomal frameshifting mechanism; this protein is similar to release factor 1; peptide chain release factor 2 664515..665492 Streptococcus pneumoniae ATCC 700669 7328292 YP_002510704.1 CDS ftsE NC_011900.1 665510 666202 D cell division ATP-binding protein 665510..666202 Streptococcus pneumoniae ATCC 700669 7327873 YP_002510705.1 CDS ftsX NC_011900.1 666195 667121 D cell division protein 666195..667121 Streptococcus pneumoniae ATCC 700669 7328568 YP_002510706.1 CDS SPN23F_06810 NC_011900.1 667407 669587 D glucose-specific phosphotransferase system (PTS), IIABC component 667407..669587 Streptococcus pneumoniae ATCC 700669 7328572 YP_002510707.1 CDS SPN23F_06820 NC_011900.1 669639 670454 D endonuclease/exonuclease/phosphatase family protein 669639..670454 Streptococcus pneumoniae ATCC 700669 7328293 YP_002510708.1 CDS SPN23F_06830 NC_011900.1 670594 671937 D helicase 670594..671937 Streptococcus pneumoniae ATCC 700669 7328294 YP_002510709.1 CDS metK NC_011900.1 672152 673342 D catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase; S-adenosylmethionine synthetase 672152..673342 Streptococcus pneumoniae ATCC 700669 7328295 YP_002510710.1 CDS pyrD NC_011900.1 673895 674830 D catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway; subclass 1A is a dimer formed by two identical PyrD subunits each containing an FMN group; dihydroorotate dehydrogenase 1A 673895..674830 Streptococcus pneumoniae ATCC 700669 7328129 YP_002510711.1 CDS holA NC_011900.1 674864 675901 D required for the assembly and function of the DNAX complex which is required for the assembly of the beta subunit onto primed DNA; DNA polymerase III subunit delta 674864..675901 Streptococcus pneumoniae ATCC 700669 7327430 YP_002510712.1 CDS sodA NC_011900.1 676042 676647 D superoxide dismutase 676042..676647 Streptococcus pneumoniae ATCC 700669 7328296 YP_002510713.1 CDS SPN23F_06890 NC_011900.1 676805 677335 D hypothetical protein 676805..677335 Streptococcus pneumoniae ATCC 700669 7329147 YP_002510714.1 CDS SPN23F_06900 NC_011900.1 677356 678258 D Appears to have undergone an in-frame deletion relative to other pneumococcal orthologues; radical SAM superfamily protein 677356..678258 Streptococcus pneumoniae ATCC 700669 7328297 YP_002510715.1 CDS SPN23F_06910 NC_011900.1 678258 678740 D VanZ like family protein 678258..678740 Streptococcus pneumoniae ATCC 700669 7328298 YP_002510716.1 CDS SPN23F_06920 NC_011900.1 678742 680283 D ABC transporter ATP-binding protein 678742..680283 Streptococcus pneumoniae ATCC 700669 7328299 YP_002510717.1 CDS SPN23F_06930 NC_011900.1 680338 681594 R IS1167A transposase complement(680338..681594) Streptococcus pneumoniae ATCC 700669 7328300 YP_002510718.1 CDS SPN23F_06940 NC_011900.1 681761 682564 R cyclophilin type peptidyl-prolyl cis-trans isomerase complement(681761..682564) Streptococcus pneumoniae ATCC 700669 7328059 YP_002510719.1 CDS SPN23F_06950 NC_011900.1 682648 682869 R hypothetical protein complement(682648..682869) Streptococcus pneumoniae ATCC 700669 7327740 YP_002510720.1 CDS rpsP NC_011900.1 683727 683999 D binds to lower part of 30S body where it stabilizes two domains; required for efficient assembly of 30S; in Escherichia coli this protein has nuclease activity; 30S ribosomal protein S16 683727..683999 Streptococcus pneumoniae ATCC 700669 7327741 YP_002510721.1 CDS SPN23F_06970 NC_011900.1 684019 684258 D hypothetical protein 684019..684258 Streptococcus pneumoniae ATCC 700669 7329122 YP_002510722.1 CDS SPN23F_06980 NC_011900.1 684834 685583 D hypothetical protein 684834..685583 Streptococcus pneumoniae ATCC 700669 7327742 YP_002510723.1 CDS rimM NC_011900.1 685653 686171 D Essential for efficient processing of 16S rRNA; 16S rRNA-processing protein RimM 685653..686171 Streptococcus pneumoniae ATCC 700669 7327743 YP_002510724.1 CDS trmD NC_011900.1 686161 686880 D methylates guanosine-37 in various tRNAs; uses S-adenosyl-L-methionine to transfer methyl group to tRNA; tRNA (guanine-N(1)-)-methyltransferase 686161..686880 Streptococcus pneumoniae ATCC 700669 7327457 YP_002510725.1 CDS SPN23F_07010 NC_011900.1 686892 687230 D ATP-binding protein 686892..687230 Streptococcus pneumoniae ATCC 700669 7327585 YP_002510726.1 CDS SPN23F_07020 NC_011900.1 687261 687581 R hypothetical protein complement(687261..687581) Streptococcus pneumoniae ATCC 700669 7327744 YP_002510727.1 CDS SPN23F_07030 NC_011900.1 687655 687894 D hypothetical protein 687655..687894 Streptococcus pneumoniae ATCC 700669 7327745 YP_002510728.1 CDS SPN23F_07040 NC_011900.1 687891 688037 R hypothetical protein complement(687891..688037) Streptococcus pneumoniae ATCC 700669 7327746 YP_002510729.1 CDS SPN23F_07050 NC_011900.1 688099 688635 R BioY family membrane protein complement(688099..688635) Streptococcus pneumoniae ATCC 700669 7327747 YP_002510730.1 CDS SPN23F_07060 NC_011900.1 689061 689399 D hypothetical protein 689061..689399 Streptococcus pneumoniae ATCC 700669 7327748 YP_002510731.1 CDS SPN23F_07070 NC_011900.1 689465 691447 D ATP/GTP-binding transport protein 689465..691447 Streptococcus pneumoniae ATCC 700669 7327749 YP_002510732.1 CDS SPN23F_07080 NC_011900.1 691444 692067 D ABC transporter ATP-binding protein 691444..692067 Streptococcus pneumoniae ATCC 700669 7327750 YP_002510733.1 CDS SPN23F_07090 NC_011900.1 692064 692564 D hypothetical protein 692064..692564 Streptococcus pneumoniae ATCC 700669 7327751 YP_002510734.1 CDS gor NC_011900.1 692730 694076 R catalyzes the reduction of 2 glutathione to glutathione disulfide; maintains high levels of reduced glutathione in the cytosol; involved in redox regulation and oxidative defense; glutathione reductase complement(692730..694076) Streptococcus pneumoniae ATCC 700669 7327752 YP_002510735.1 CDS SPN23F_07110 NC_011900.1 694341 695540 D hypothetical protein 694341..695540 Streptococcus pneumoniae ATCC 700669 7328618 YP_002510736.1 CDS SPN23F_07120 NC_011900.1 695524 696225 D ABC transporter ATP-binding protein 695524..696225 Streptococcus pneumoniae ATCC 700669 7327753 YP_002510737.1 CDS SPN23F_07130 NC_011900.1 696227 697486 D permease 696227..697486 Streptococcus pneumoniae ATCC 700669 7327754 YP_002510738.1 CDS metG NC_011900.1 697610 699607 D methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content; methionyl-tRNA synthetase 697610..699607 Streptococcus pneumoniae ATCC 700669 7327755 YP_002510739.1 CDS SPN23F_07160 NC_011900.1 699938 700258 D PadR family transcriptional regulator 699938..700258 Streptococcus pneumoniae ATCC 700669 7328128 YP_002510740.1 CDS SPN23F_07170 NC_011900.1 700262 701077 D hypothetical protein 700262..701077 Streptococcus pneumoniae ATCC 700669 7327756 YP_002510741.1 CDS SPN23F_07180 NC_011900.1 701152 702078 D oxidoreductase 701152..702078 Streptococcus pneumoniae ATCC 700669 7327757 YP_002510742.1 CDS SPN23F_07190 NC_011900.1 702174 702410 D hypothetical protein 702174..702410 Streptococcus pneumoniae ATCC 700669 7327758 YP_002510743.1 CDS fabG NC_011900.1 702403 703101 D Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis; 3-ketoacyl-ACP reductase 702403..703101 Streptococcus pneumoniae ATCC 700669 7327759 YP_002510744.1 CDS SPN23F_07210 NC_011900.1 703112 703591 D NUDIX family protein 703112..703591 Streptococcus pneumoniae ATCC 700669 7327760 YP_002510745.1 CDS SPN23F_07220 NC_011900.1 703599 704327 D GNAT family acetyltransferase 703599..704327 Streptococcus pneumoniae ATCC 700669 7327761 YP_002510746.1 CDS SPN23F_07230 NC_011900.1 704369 705238 D PEP-utilizing enzyme 704369..705238 Streptococcus pneumoniae ATCC 700669 7327762 YP_002510747.1 CDS SPN23F_07240 NC_011900.1 705213 705653 D hypothetical protein 705213..705653 Streptococcus pneumoniae ATCC 700669 7327763 YP_002510748.1 CDS pepN NC_011900.1 705776 708322 D lysyl-aminopeptidase 705776..708322 Streptococcus pneumoniae ATCC 700669 7327764 YP_002510749.1 CDS SPN23F_07260 NC_011900.1 708380 709636 R IS1167A transposase complement(708380..709636) Streptococcus pneumoniae ATCC 700669 7327826 YP_002510750.1 CDS ciaR NC_011900.1 709854 710528 D response regulator protein 709854..710528 Streptococcus pneumoniae ATCC 700669 7327765 YP_002510751.1 CDS ciaH NC_011900.1 710518 711852 D sensor histidine kinase 710518..711852 Streptococcus pneumoniae ATCC 700669 7329193 YP_002510752.1 CDS SPN23F_07290 NC_011900.1 711886 712173 R hypothetical protein complement(711886..712173) Streptococcus pneumoniae ATCC 700669 7329192 YP_002510753.1 CDS SPN23F_07300 NC_011900.1 712313 713242 D peptidase 712313..713242 Streptococcus pneumoniae ATCC 700669 7327766 YP_002510754.1 CDS SPN23F_07310 NC_011900.1 713442 715892 D unwinds DNA; bifunctional ATP-dependent DNA helicase/DNA polymerase III subunit epsilon 713442..715892 Streptococcus pneumoniae ATCC 700669 7327767 YP_002510755.1 CDS SPN23F_07320 NC_011900.1 715929 717152 D peptidoglycan biosynthesis membrane protein 715929..717152 Streptococcus pneumoniae ATCC 700669 7327768 YP_002510756.1 CDS SPN23F_07330 NC_011900.1 717163 717717 D DJ-1/PfpI family protein 717163..717717 Streptococcus pneumoniae ATCC 700669 7327769 YP_002510757.1 CDS SPN23F_07340 NC_011900.1 717802 718365 D haloacid dehalogenase-like hydrolase 717802..718365 Streptococcus pneumoniae ATCC 700669 7327770 YP_002510758.1 CDS gyrB NC_011900.1 718380 720326 D negatively supercoils closed circular double-stranded DNA; DNA gyrase subunit B 718380..720326 Streptococcus pneumoniae ATCC 700669 7327771 YP_002510759.1 CDS ezrA NC_011900.1 720408 722135 D acts to negatively regulates ftsZ ring formation by modulating the frequency and position of the ftsZ ring formation; septation ring formation regulator EzrA 720408..722135 Streptococcus pneumoniae ATCC 700669 7328066 YP_002510760.1 CDS SPN23F_07380 NC_011900.1 723448 723747 R hypothetical protein complement(723448..723747) Streptococcus pneumoniae ATCC 700669 7327772 YP_002510761.1 CDS SPN23F_07390 NC_011900.1 723912 724334 R MutT/NUDIX hydrolase family protein complement(723912..724334) Streptococcus pneumoniae ATCC 700669 7327773 YP_002510762.1 CDS clpE NC_011900.1 725499 727757 R ATP-dependent Clp protease ATP-binding subunit complement(725499..727757) Streptococcus pneumoniae ATCC 700669 7327775 YP_002510763.1 CDS SPN23F_07430 NC_011900.1 727986 728216 R hypothetical protein complement(727986..728216) Streptococcus pneumoniae ATCC 700669 7329196 YP_002510764.1 CDS SPN23F_07440 NC_011900.1 728406 729089 D amino acid ABC transporter permease 728406..729089 Streptococcus pneumoniae ATCC 700669 7327776 YP_002510765.1 CDS glnQ3 NC_011900.1 729089 729823 D glutamine transporter, ATP-binding protein 3 729089..729823 Streptococcus pneumoniae ATCC 700669 7327777 YP_002510766.1 CDS folD NC_011900.1 729956 730834 D catalyzes the formation of 5,10-methenyltetrahydrofolate from 5,10-methylenetetrahydrofolate and subsequent formation of 10-formyltetrahydrofolate from 5,10-methenyltetrahydrofolate; bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase 729956..730834 Streptococcus pneumoniae ATCC 700669 7328605 YP_002510767.1 CDS SPN23F_07470 NC_011900.1 730971 731792 D hypothetical protein 730971..731792 Streptococcus pneumoniae ATCC 700669 7328559 YP_002510768.1 CDS SPN23F_07480 NC_011900.1 731806 732645 D carbohydrate kinase 731806..732645 Streptococcus pneumoniae ATCC 700669 7327778 YP_002510769.1 CDS rpiA NC_011900.1 732943 733626 D Catalyzes D-ribose 5-phosphate --> D-ribulose 5-phosphate in the nonoxidative branch of the pentose phosphate pathway; ribose-5-phosphate isomerase A 732943..733626 Streptococcus pneumoniae ATCC 700669 7327779 YP_002510770.1 CDS deoB NC_011900.1 733640 734851 D catalyzes the transfer of phosphate between the C1 and C5 carbons of pentose; phosphopentomutase 733640..734851 Streptococcus pneumoniae ATCC 700669 7327469 YP_002510771.1 CDS SPN23F_07510 NC_011900.1 734853 735395 D hypothetical protein 734853..735395 Streptococcus pneumoniae ATCC 700669 7329226 YP_002510772.1 CDS punA NC_011900.1 735411 736220 D catalyzes the formation of a purine and ribose phosphate from a purine nucleoside; in E. coli this enzyme functions in xanthosine degradation; purine nucleoside phosphorylase 735411..736220 Streptococcus pneumoniae ATCC 700669 7327780 YP_002510773.1 CDS deoD NC_011900.1 738866 739576 D catalyzes the reversible phosphorolysis of ribonucleosides and 2'- deoxyribonucleosides to the free base and (2'-deoxy)ribose-1- phosphate; purine nucleoside phosphorylase 738866..739576 Streptococcus pneumoniae ATCC 700669 7327782 YP_002510774.1 CDS SPN23F_07580 NC_011900.1 739599 740123 R topology modulation protein complement(739599..740123) Streptococcus pneumoniae ATCC 700669 7329228 YP_002510775.1 CDS rpsT NC_011900.1 740176 740412 R binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase; 30S ribosomal protein S20 complement(740176..740412) Streptococcus pneumoniae ATCC 700669 7327783 YP_002510776.1 CDS coaA NC_011900.1 740480 741400 R catalyzes the formation of (R)-4'-phosphopantothenate in coenzyme A biosynthesis; pantothenate kinase complement(740480..741400) Streptococcus pneumoniae ATCC 700669 7329126 YP_002510777.1 CDS SPN23F_07620 NC_011900.1 742209 742790 D methyltransferase 742209..742790 Streptococcus pneumoniae ATCC 700669 7327784 YP_002510778.1 CDS deoA NC_011900.1 742787 744064 D Catalyzes the reversible phosphorolysis of pyrimidines in the nucleotide synthesis salvage pathway; pyrimidine-nucleoside phosphorylase 742787..744064 Streptococcus pneumoniae ATCC 700669 7327785 YP_002510779.1 CDS deoC NC_011900.1 744082 744744 D catalyzes the formation of D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-D-ribose-5-phosphate; deoxyribose-phosphate aldolase 744082..744744 Streptococcus pneumoniae ATCC 700669 7329225 YP_002510780.1 CDS cdd NC_011900.1 744731 745120 D Reclaims exogenous and endogenous cytidine and 2'-deoxycytidine molecules for UMP synthesis; cytidine deaminase 744731..745120 Streptococcus pneumoniae ATCC 700669 7329227 YP_002510781.1 CDS SPN23F_07660 NC_011900.1 745211 746263 D lipoprotein 745211..746263 Streptococcus pneumoniae ATCC 700669 7329191 YP_002510782.1 CDS SPN23F_07670 NC_011900.1 746407 747942 D ABC transporter ATP-binding protein 746407..747942 Streptococcus pneumoniae ATCC 700669 7327786 YP_002510783.1 CDS SPN23F_07680 NC_011900.1 747935 748993 D ABC transporter permease 747935..748993 Streptococcus pneumoniae ATCC 700669 7327787 YP_002510784.1 CDS SPN23F_07690 NC_011900.1 748996 749952 D ABC transporter permease 748996..749952 Streptococcus pneumoniae ATCC 700669 7327788 YP_002510785.1 CDS SPN23F_07720 NC_011900.1 750553 751386 D IS3-Spn1 orf B 750553..751386 Streptococcus pneumoniae ATCC 700669 7327790 YP_002510786.1 CDS SPN23F_07730 NC_011900.1 751429 752070 R involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsX; glycerol-3-phosphate acyltransferase PlsY complement(751429..752070) Streptococcus pneumoniae ATCC 700669 7327791 YP_002510787.1 CDS parE NC_011900.1 752206 754149 D decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling; DNA topoisomerase IV subunit B 752206..754149 Streptococcus pneumoniae ATCC 700669 7327792 YP_002510788.1 CDS parC NC_011900.1 754605 757040 D decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling; DNA topoisomerase IV subunit A 754605..757040 Streptococcus pneumoniae ATCC 700669 7328452 YP_002510789.1 CDS SPN23F_07770 NC_011900.1 757172 758194 D catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids; branched-chain amino acid aminotransferase 757172..758194 Streptococcus pneumoniae ATCC 700669 7328451 YP_002510790.1 CDS SPN23F_07780 NC_011900.1 758250 758954 D extracellular oligopeptide-binding protein 758250..758954 Streptococcus pneumoniae ATCC 700669 7327793 YP_002510791.1 CDS SPN23F_07790 NC_011900.1 759019 759708 D hypothetical protein 759019..759708 Streptococcus pneumoniae ATCC 700669 7327794 YP_002510792.1 CDS SPN23F_07800 NC_011900.1 759705 760628 D hypothetical protein 759705..760628 Streptococcus pneumoniae ATCC 700669 7327795 YP_002510793.1 CDS pcp NC_011900.1 760643 761287 D catalyzes the removal of 5-oxoproline from various penultimate amino acid residues except L-proline; pyrrolidone-carboxylate peptidase 760643..761287 Streptococcus pneumoniae ATCC 700669 7327796 YP_002510794.1 CDS SPN23F_07820 NC_011900.1 761455 761685 D hypothetical protein 761455..761685 Streptococcus pneumoniae ATCC 700669 7328459 YP_002510795.1 CDS rpsA NC_011900.1 762058 763260 D in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins; 30S ribosomal protein S1 762058..763260 Streptococcus pneumoniae ATCC 700669 7327601 YP_002510796.1 CDS SPN23F_07870 NC_011900.1 764840 765337 D hypothetical protein 764840..765337 Streptococcus pneumoniae ATCC 700669 7327800 YP_002510797.1 CDS dnaH NC_011900.1 765337 766992 D catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the tau chain serves as a scaffold to help in the dimerizaton of the alpha,epsilon and theta core complex; the gamma chain seems to interact with the delta and delta' subunits to transfer the beta subunit on the DNA; DNA polymerase III subunits gamma/tau 765337..766992 Streptococcus pneumoniae ATCC 700669 7327801 YP_002510798.1 CDS sufC NC_011900.1 767364 768134 D FeS assembly ATPase SufC, ABC transporter ATP-binding protein 767364..768134 Streptococcus pneumoniae ATCC 700669 7329242 YP_002510799.1 CDS sufD NC_011900.1 768162 769424 D FeS assembly protein SufD 768162..769424 Streptococcus pneumoniae ATCC 700669 7329160 YP_002510800.1 CDS csdB NC_011900.1 769435 770661 D cysteine desulfurase 769435..770661 Streptococcus pneumoniae ATCC 700669 7329161 YP_002510801.1 CDS iscU NC_011900.1 770648 771088 D FeS assembly NifU-like protein 770648..771088 Streptococcus pneumoniae ATCC 700669 7329214 YP_002510802.1 CDS sufB NC_011900.1 771142 772554 D FeS assembly protein SufB 771142..772554 Streptococcus pneumoniae ATCC 700669 7328088 YP_002510803.1 CDS SPN23F_07950 NC_011900.1 772753 773994 R D-alanyl-D-alanine carboxypeptidase complement(772753..773994) Streptococcus pneumoniae ATCC 700669 7329159 YP_002510804.1 CDS SPN23F_07960 NC_011900.1 774175 775206 D hypothetical protein 774175..775206 Streptococcus pneumoniae ATCC 700669 7327802 YP_002510805.1 CDS SPN23F_07970 NC_011900.1 776632 777372 D DeoR family regulatory protein 776632..777372 Streptococcus pneumoniae ATCC 700669 7327632 YP_002510806.1 CDS fruK NC_011900.1 777369 778280 D 1-phosphofructokinase 777369..778280 Streptococcus pneumoniae ATCC 700669 7327804 YP_002510807.1 CDS fruA NC_011900.1 778277 780229 D fructose-specific phosphotransferase system (PTS), IIABC component 778277..780229 Streptococcus pneumoniae ATCC 700669 7328565 YP_002510808.1 CDS SPN23F_08010 NC_011900.1 780393 782618 D DNA translocase FtsK 780393..782618 Streptococcus pneumoniae ATCC 700669 7328564 YP_002510809.1 CDS SPN23F_08020 NC_011900.1 782769 783197 R hypothetical protein complement(782769..783197) Streptococcus pneumoniae ATCC 700669 7327805 YP_002510810.1 CDS SPN23F_08030 NC_011900.1 783335 784477 D cysteine desulfhydrase 783335..784477 Streptococcus pneumoniae ATCC 700669 7327806 YP_002510811.1 CDS thiI NC_011900.1 784486 785700 D Required for the synthesis of the thiazole moiety; thiamine biosynthesis protein ThiI 784486..785700 Streptococcus pneumoniae ATCC 700669 7327807 YP_002510812.1 CDS SPN23F_08050 NC_011900.1 785835 786659 D esterase 785835..786659 Streptococcus pneumoniae ATCC 700669 7329170 YP_002510813.1 CDS SPN23F_08060 NC_011900.1 786672 787838 D hypothetical protein 786672..787838 Streptococcus pneumoniae ATCC 700669 7327808 YP_002510814.1 CDS SPN23F_08070 NC_011900.1 788346 789839 D type I RM modification enzyme 788346..789839 Streptococcus pneumoniae ATCC 700669 7327809 YP_002510815.1 CDS SPN23F_08080 NC_011900.1 789852 790394 D type I RM modification enzyme 789852..790394 Streptococcus pneumoniae ATCC 700669 7327810 YP_002510816.1 CDS SPN23F_08090 NC_011900.1 790391 791509 D type I RM modification enzyme 790391..791509 Streptococcus pneumoniae ATCC 700669 7327811 YP_002510817.1 CDS SPN23F_08100 NC_011900.1 791569 791805 D hypothetical protein 791569..791805 Streptococcus pneumoniae ATCC 700669 7327812 YP_002510818.1 CDS SPN23F_08110 NC_011900.1 791802 792215 D Phage/plasmid maintenance toxin/antidote system protein (toxin) 791802..792215 Streptococcus pneumoniae ATCC 700669 7327813 YP_002510819.1 CDS SPN23F_08120 NC_011900.1 792333 793298 D integrase/recombinase 792333..793298 Streptococcus pneumoniae ATCC 700669 7327814 YP_002510820.1 CDS SPN23F_08130 NC_011900.1 793264 793845 D type I RM modification enzyme 793264..793845 Streptococcus pneumoniae ATCC 700669 7327815 YP_002510821.1 CDS SPN23F_08140 NC_011900.1 793875 797225 D type I restriction modification system restriction protein 793875..797225 Streptococcus pneumoniae ATCC 700669 7327816 YP_002510822.1 CDS argR NC_011900.1 797731 798201 R arginine repressor complement(797731..798201) Streptococcus pneumoniae ATCC 700669 7327817 YP_002510823.1 CDS pepXP NC_011900.1 798218 800491 R catalyzes the removal of N-terminal dipeptides when proline is the penultimate residue; x-prolyl-dipeptidyl aminopeptidase complement(798218..800491) Streptococcus pneumoniae ATCC 700669 7328655 YP_002510824.1 CDS dnaE NC_011900.1 800837 803938 D Catalyzes DNA-template-directed extension of the 3'-end of a DNA strand by one nucleotide at a time. Proposed to be responsible for the synthesis of the lagging strand. In the low GC gram positive bacteria this enzyme is less processive and more error prone than its counterpart in other bacteria.; DNA polymerase III DnaE 800837..803938 Streptococcus pneumoniae ATCC 700669 7327832 YP_002510825.1 CDS pfk NC_011900.1 804021 805028 D catalyzes the formation of D-fructose 1,6-bisphosphate from D-fructose 6-phosphate in glycolysis; 6-phosphofructokinase 804021..805028 Streptococcus pneumoniae ATCC 700669 7329240 YP_002510826.1 CDS pyk NC_011900.1 805087 806592 D catalyzes the formation of phosphoenolpyruvate from pyruvate; pyruvate kinase 805087..806592 Streptococcus pneumoniae ATCC 700669 7327833 YP_002510827.1 CDS SPN23F_08210 NC_011900.1 808407 809279 D lipoprotein 808407..809279 Streptococcus pneumoniae ATCC 700669 7327818 YP_002510828.1 CDS SPN23F_08220 NC_011900.1 809386 809769 R IS1381 transposase complement(809386..809769) Streptococcus pneumoniae ATCC 700669 7328862 YP_002510829.1 CDS SPN23F_08230 NC_011900.1 809912 810223 D hypothetical protein 809912..810223 Streptococcus pneumoniae ATCC 700669 7328864 YP_002510830.1 CDS SPN23F_08240 NC_011900.1 810227 810943 D hypothetical protein 810227..810943 Streptococcus pneumoniae ATCC 700669 7328865 YP_002510831.1 CDS SPN23F_08250 NC_011900.1 811073 811888 R hypothetical protein complement(811073..811888) Streptococcus pneumoniae ATCC 700669 7328866 YP_002510832.1 CDS SPN23F_08260 NC_011900.1 811885 812790 R permease complement(811885..812790) Streptococcus pneumoniae ATCC 700669 7328867 YP_002510833.1 CDS SPN23F_08270 NC_011900.1 812791 812922 R hypothetical protein complement(812791..812922) Streptococcus pneumoniae ATCC 700669 7328868 YP_002510834.1 CDS SPN23F_08280 NC_011900.1 813036 813221 R hypothetical protein complement(813036..813221) Streptococcus pneumoniae ATCC 700669 7328869 YP_002510835.1 CDS SPN23F_08290 NC_011900.1 813337 815466 D transcription accessory protein 813337..815466 Streptococcus pneumoniae ATCC 700669 7328870 YP_002510836.1 CDS SPN23F_08300 NC_011900.1 815453 815902 D hypothetical protein 815453..815902 Streptococcus pneumoniae ATCC 700669 7328871 YP_002510837.1 CDS SPN23F_08310 NC_011900.1 815961 816233 D hypothetical protein 815961..816233 Streptococcus pneumoniae ATCC 700669 7328872 YP_002510838.1 CDS SPN23F_08320 NC_011900.1 816281 816445 R hypothetical protein complement(816281..816445) Streptococcus pneumoniae ATCC 700669 7328873 YP_002510839.1 CDS SPN23F_08321 NC_011900.1 816587 816778 R hypothetical protein complement(816587..816778) Streptococcus pneumoniae ATCC 700669 7328874 YP_002510840.1 CDS SPN23F_08330 NC_011900.1 817206 817964 D ABC transporter ATP-binding protein 817206..817964 Streptococcus pneumoniae ATCC 700669 7328875 YP_002510841.1 CDS SPN23F_08340 NC_011900.1 817966 819954 D ABC transporter permease 817966..819954 Streptococcus pneumoniae ATCC 700669 7328876 YP_002510842.1 CDS speA NC_011900.1 822368 823843 D arginine decarboxylase 822368..823843 Streptococcus pneumoniae ATCC 700669 7328880 YP_002510843.1 CDS speE NC_011900.1 824780 825640 D catalyzes the formation of spermidine from putrescine and S-adenosylmethioninamine; spermidine synthase 824780..825640 Streptococcus pneumoniae ATCC 700669 7328882 YP_002510844.1 CDS SPN23F_08430 NC_011900.1 825637 826896 D saccharopine dehydrogenase family protein 825637..826896 Streptococcus pneumoniae ATCC 700669 7329149 YP_002510845.1 CDS SPN23F_08440 NC_011900.1 826896 828023 D carboxynorspermidine decarboxylase 826896..828023 Streptococcus pneumoniae ATCC 700669 7328883 YP_002510846.1 CDS SPN23F_08450 NC_011900.1 828020 829105 D catalyzes the formation of carbamoylputrescine from agmatine in the arginine decarboxylase pathway of putrescine biosynthesis; agmatine deiminase 828020..829105 Streptococcus pneumoniae ATCC 700669 7328884 YP_002510847.1 CDS SPN23F_08460 NC_011900.1 829115 829990 D carbon-nitrogen hydrolase family protein 829115..829990 Streptococcus pneumoniae ATCC 700669 7328885 YP_002510848.1 CDS SPN23F_08470 NC_011900.1 830171 830980 R haloacid dehalogenase-like hydrolase complement(830171..830980) Streptococcus pneumoniae ATCC 700669 7328886 YP_002510849.1 CDS SPN23F_08480 NC_011900.1 831527 832198 D hypothetical protein 831527..832198 Streptococcus pneumoniae ATCC 700669 7328887 YP_002510850.1 CDS SPN23F_08500 NC_011900.1 832440 833348 D LysR family transcriptional regulator 832440..833348 Streptococcus pneumoniae ATCC 700669 7328888 YP_002510851.1 CDS lspA NC_011900.1 833345 833806 D lipoprotein signal peptidase; integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis; lipoprotein signal peptidase 833345..833806 Streptococcus pneumoniae ATCC 700669 7328889 YP_002510852.1 CDS SPN23F_08520 NC_011900.1 833796 834683 D RNA pseudouridylate synthase 833796..834683 Streptococcus pneumoniae ATCC 700669 7328111 YP_002510853.1 CDS cbpE NC_011900.1 834686 836569 D choline binding protein E 834686..836569 Streptococcus pneumoniae ATCC 700669 7328890 YP_002510854.1 CDS proB NC_011900.1 836670 837779 D catalyzes the formation of glutamate 5-phosphate from glutamate in proline biosynthesis; gamma-glutamyl kinase 836670..837779 Streptococcus pneumoniae ATCC 700669 7329182 YP_002510855.1 CDS proA NC_011900.1 837789 839051 D Catalyzes the phosphorylation of L-glutamate during the proline biosynthesis pathway; gamma-glutamyl phosphate reductase 837789..839051 Streptococcus pneumoniae ATCC 700669 7327877 YP_002510856.1 CDS proC NC_011900.1 839055 839852 D pyrroline-5-carboxylate reductase 839055..839852 Streptococcus pneumoniae ATCC 700669 7327876 YP_002510857.1 CDS tmk NC_011900.1 840072 840710 D catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to thymidine monophosphate (dTMP) to form thymidine diphosphate (dTDP); thymidylate kinase 840072..840710 Streptococcus pneumoniae ATCC 700669 7327878 YP_002510858.1 CDS holB NC_011900.1 840707 841597 D catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the delta' subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA.; DNA polymerase III subunit delta' 840707..841597 Streptococcus pneumoniae ATCC 700669 7329178 YP_002510859.1 CDS SPN23F_08590 NC_011900.1 841637 841954 D in Bacillus subtilis this protein is involved in the negative regulation of DNA replication initiation; interacts with DnaN and DnaA; DNA replication intiation control protein YabA 841637..841954 Streptococcus pneumoniae ATCC 700669 7328073 YP_002510860.1 CDS SPN23F_08600 NC_011900.1 841957 842826 D tetrapyrrole methylase 841957..842826 Streptococcus pneumoniae ATCC 700669 7328891 YP_002510861.1 CDS SPN23F_08610 NC_011900.1 843053 843571 D hypothetical protein 843053..843571 Streptococcus pneumoniae ATCC 700669 7328892 YP_002510862.1 CDS SPN23F_08650 NC_011900.1 845667 847001 D TrmFO; Gid; glucose-inhibited division protein; similar to GidA; the gene from Bacillus subtilis encodes a tRNA-methyltransferase that utilizes folate as the carbon donor and bound flavin as reductant; modifies tRNA at position 54 (uridine) of the T-psi loop to form a C5-methyluridine; tRNA (uracil-5-)-methyltransferase Gid 845667..847001 Streptococcus pneumoniae ATCC 700669 7328895 YP_002510863.1 CDS pyrH NC_011900.1 847085 847822 D Catalyzes the phosphorylation of UMP to UDP; uridylate kinase 847085..847822 Streptococcus pneumoniae ATCC 700669 7328896 YP_002510864.1 CDS frr NC_011900.1 847831 848388 D Rrf; Frr; ribosome-recycling factor; release factor 4; RF4; recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G; A GTPase-dependent process results in release of 50S from 70S; inhibited by release factor RF-1; essential for viability; structurally similar to tRNAs; ribosome recycling factor 847831..848388 Streptococcus pneumoniae ATCC 700669 7327435 YP_002510865.1 CDS SPN23F_08680 NC_011900.1 848409 849302 D hypothetical protein 848409..849302 Streptococcus pneumoniae ATCC 700669 7329128 YP_002510866.1 CDS SPN23F_08690 NC_011900.1 849311 849526 D hypothetical protein 849311..849526 Streptococcus pneumoniae ATCC 700669 7328897 YP_002510867.1 CDS SPN23F_08700 NC_011900.1 849612 850580 D PhoH-like protein 849612..850580 Streptococcus pneumoniae ATCC 700669 7328898 YP_002510868.1 CDS SPN23F_08740 NC_011900.1 851277 851504 D competence-related protein 851277..851504 Streptococcus pneumoniae ATCC 700669 7328901 YP_002510869.1 CDS SPN23F_08780 NC_011900.1 853191 853760 D GNAT family acetyltransferase 853191..853760 Streptococcus pneumoniae ATCC 700669 7328902 YP_002510870.1 CDS comEA NC_011900.1 853828 854478 D competence protein 853828..854478 Streptococcus pneumoniae ATCC 700669 7328903 YP_002510871.1 CDS comEC NC_011900.1 854462 856702 D competence protein 854462..856702 Streptococcus pneumoniae ATCC 700669 7329207 YP_002510872.1 CDS SPN23F_08820 NC_011900.1 857101 857688 D ABC transporter ATP-binding protein 857101..857688 Streptococcus pneumoniae ATCC 700669 7329208 YP_002510873.1 CDS SPN23F_08830 NC_011900.1 857692 858873 D hypothetical protein 857692..858873 Streptococcus pneumoniae ATCC 700669 7328904 YP_002510874.1 CDS infC NC_011900.1 859153 859710 D IF-3 has several functions that are required and promote translation initiation including; preventing association of 70S by binding to 30S; monitoring codon-anticodon interactions by promoting disassociation of fMet-tRNA(fMet) from initiation complexes formed on leaderless mRNAs or incorrectly bound noninitiatior tRNAs and complexes with noncanonical start sites; stimulates codon-anticodon interactions at P-site; involved in moving mRNA to the P-site; and in recycling subunits; translation initiation factor IF-3 859153..859710 Streptococcus pneumoniae ATCC 700669 7328905 YP_002510875.1 CDS rpmI NC_011900.1 859743 859943 D 50S ribosomal protein L35 859743..859943 Streptococcus pneumoniae ATCC 700669 7328087 YP_002510876.1 CDS rplT NC_011900.1 859995 860354 D binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit; 50S ribosomal protein L20 859995..860354 Streptococcus pneumoniae ATCC 700669 7329102 YP_002510877.1 CDS gloA NC_011900.1 860412 860792 D lactoylglutathione lyase 860412..860792 Streptococcus pneumoniae ATCC 700669 7327487 YP_002510878.1 CDS pyrK NC_011900.1 861042 861842 D responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the pyrD subunit to the ultimate electron acceptor NAD(+); dihydroorotate dehydrogenase electron transfer subunit 861042..861842 Streptococcus pneumoniae ATCC 700669 7328607 YP_002510879.1 CDS pyrD NC_011900.1 861853 862791 D catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway, using a flavin nucleotide as an essential cofactor; subclass 1B is a heterotetramer consisting of two PyrDB subunits, similar to the PyrDA subunits and two PyrK subunits; dihydroorotate dehydrogenase 1B 861853..862791 Streptococcus pneumoniae ATCC 700669 7327436 YP_002510880.1 CDS lytB NC_011900.1 862890 864866 D endo-beta-N-acetylglucosaminidase 862890..864866 Streptococcus pneumoniae ATCC 700669 7327431 YP_002510881.1 CDS fbpS NC_011900.1 864927 866582 R fibronectin/fibrinogen-binding protein adherence and virulence protein A complement(864927..866582) Streptococcus pneumoniae ATCC 700669 7328114 YP_002510882.1 CDS SPN23F_08920 NC_011900.1 866687 867184 D metalloprotease 866687..867184 Streptococcus pneumoniae ATCC 700669 7328552 YP_002510883.1 CDS dgk NC_011900.1 867165 867560 D diacylglycerol kinase 867165..867560 Streptococcus pneumoniae ATCC 700669 7328906 YP_002510884.1 CDS era NC_011900.1 867577 868476 D Era; Escherichia coli Ras-like protein; Bex; Bacillus Era-complementing segment; essential protein in Escherichia coli that is involved in many cellular processes; GTPase; binds the cell membrane through apparent C-terminal domain; mutants are arrested during the cell cycle; Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome; GTP-binding protein Era 867577..868476 Streptococcus pneumoniae ATCC 700669 7329230 YP_002510885.1 CDS fpg NC_011900.1 868525 869349 D Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases; formamidopyrimidine-DNA glycosylase 868525..869349 Streptococcus pneumoniae ATCC 700669 7329258 YP_002510886.1 CDS coaE NC_011900.1 869349 869954 D catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; involved in coenzyme A biosynthesis; dephospho-CoA kinase 869349..869954 Streptococcus pneumoniae ATCC 700669 7328562 YP_002510887.1 CDS pmrA NC_011900.1 869941 871140 D multi-drug resistance efflux pump 869941..871140 Streptococcus pneumoniae ATCC 700669 7329204 YP_002510888.1 CDS secG NC_011900.1 871329 871562 D preprotein translocase subunit SecG 871329..871562 Streptococcus pneumoniae ATCC 700669 7327855 YP_002510889.1 CDS rnr NC_011900.1 871664 874018 D exoribonuclease R 871664..874018 Streptococcus pneumoniae ATCC 700669 7329141 YP_002510890.1 CDS smpB NC_011900.1 873981 874448 D binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation; SsrA-binding protein 873981..874448 Streptococcus pneumoniae ATCC 700669 7327466 YP_002510891.1 CDS SPN23F_09010 NC_011900.1 874464 875324 D with TehA confers resistance to tellurite; tellurite resistance protein TehB 874464..875324 Streptococcus pneumoniae ATCC 700669 7329145 YP_002510892.1 CDS SPN23F_09020 NC_011900.1 875397 876350 D competence protein CoiA-like family protein 875397..876350 Streptococcus pneumoniae ATCC 700669 7328907 YP_002510893.1 CDS pepB NC_011900.1 876369 878171 D oligopeptidase 876369..878171 Streptococcus pneumoniae ATCC 700669 7328908 YP_002510894.1 CDS SPN23F_09040 NC_011900.1 878209 878886 D O-methyltransferase 878209..878886 Streptococcus pneumoniae ATCC 700669 7327824 YP_002510895.1 CDS prsA NC_011900.1 878953 879894 D cis/trans isomerase of peptidylprolyl; PPIase; membrane-bound lipoprotein; foldase protein PrsA 878953..879894 Streptococcus pneumoniae ATCC 700669 7328909 YP_002510896.1 CDS SPN23F_09090 NC_011900.1 881115 881735 R phosphoglycerate mutase family protein complement(881115..881735) Streptococcus pneumoniae ATCC 700669 7328912 YP_002510897.1 CDS SPN23F_09100 NC_011900.1 881735 882217 R hypothetical protein complement(881735..882217) Streptococcus pneumoniae ATCC 700669 7328913 YP_002510898.1 CDS SPN23F_09110 NC_011900.1 882217 883059 R hypothetical protein complement(882217..883059) Streptococcus pneumoniae ATCC 700669 7328914 YP_002510899.1 CDS SPN23F_09120 NC_011900.1 883154 883954 R glycosyl hydrolase complement(883154..883954) Streptococcus pneumoniae ATCC 700669 7328915 YP_002510900.1 CDS glmU NC_011900.1 884050 885477 D forms a homotrimer; catalyzes the acetylation of glucosamine-1-phosphate and uridylation of N-acetylglucosamine-1-phosphate to produce UDP-GlcNAc; function in cell wall synthesis; bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase 884050..885477 Streptococcus pneumoniae ATCC 700669 7328916 YP_002510901.1 CDS SPN23F_09140 NC_011900.1 885487 886032 D ADP-ribose pyrophosphatase 885487..886032 Streptococcus pneumoniae ATCC 700669 7328589 YP_002510902.1 CDS SPN23F_09150 NC_011900.1 886044 886358 D hypothetical protein 886044..886358 Streptococcus pneumoniae ATCC 700669 7328917 YP_002510903.1 CDS mtnN NC_011900.1 886375 887067 D enables the cleavage of the glycosidic bond in both 5'-methylthioadenosine and S-adenosylhomocysteine; 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase 886375..887067 Streptococcus pneumoniae ATCC 700669 7328918 YP_002510904.1 CDS SPN23F_09170 NC_011900.1 887156 887635 D DNA-binding protein 887156..887635 Streptococcus pneumoniae ATCC 700669 7328387 YP_002510905.1 CDS SPN23F_09180 NC_011900.1 887733 888323 D 3'-5' exonuclease of DNA polymerase III; DNA polymerase III subunit epsilon 887733..888323 Streptococcus pneumoniae ATCC 700669 7328919 YP_002510906.1 CDS SPN23F_09190 NC_011900.1 888332 890095 D glycerophosphodiester phosphodiesterase 888332..890095 Streptococcus pneumoniae ATCC 700669 7328920 YP_002510907.1 CDS SPN23F_09220 NC_011900.1 891118 891318 D hypothetical protein 891118..891318 Streptococcus pneumoniae ATCC 700669 7328922 YP_002510908.1 CDS SPN23F_09250 NC_011900.1 891996 892703 D cytochrome c-type biogenesis protein 891996..892703 Streptococcus pneumoniae ATCC 700669 7328924 YP_002510909.1 CDS SPN23F_09260 NC_011900.1 892714 893271 D redoxin family protein 892714..893271 Streptococcus pneumoniae ATCC 700669 7328926 YP_002510910.1 CDS SPN23F_09270 NC_011900.1 893645 895036 D amino acid permease 893645..895036 Streptococcus pneumoniae ATCC 700669 7328927 YP_002510911.1 CDS lmb NC_011900.1 895179 896096 D laminin binding protein 895179..896096 Streptococcus pneumoniae ATCC 700669 7328928 YP_002510912.1 CDS phtD NC_011900.1 896104 898620 D pneumococcal histidine triad protein D (bvh-11-2) 896104..898620 Streptococcus pneumoniae ATCC 700669 7328110 YP_002510913.1 CDS phtE NC_011900.1 898830 901949 D pneumococcal histidine triad protein E (Bvh-3) 898830..901949 Streptococcus pneumoniae ATCC 700669 7327848 YP_002510914.1 CDS SPN23F_09310 NC_011900.1 902779 903348 D pneumococcal histidine triad protein E truncation 902779..903348 Streptococcus pneumoniae ATCC 700669 7327850 YP_002510915.1 CDS pepT NC_011900.1 904308 905531 R catalyzes the release of the N-terminal amino acid from a tripeptide; peptidase T complement(904308..905531) Streptococcus pneumoniae ATCC 700669 7328930 YP_002510916.1 CDS hemH NC_011900.1 905686 906780 D ferrochelatase 905686..906780 Streptococcus pneumoniae ATCC 700669 7327830 YP_002510917.1 CDS mscL NC_011900.1 906822 907199 R large-conductance mechanosensitive channel complement(906822..907199) Streptococcus pneumoniae ATCC 700669 7328068 YP_002510918.1 CDS SPN23F_09360 NC_011900.1 907281 907712 R GtrA-like protein complement(907281..907712) Streptococcus pneumoniae ATCC 700669 7328134 YP_002510919.1 CDS SPN23F_09370 NC_011900.1 907835 908344 D hypothetical protein 907835..908344 Streptococcus pneumoniae ATCC 700669 7328931 YP_002510920.1 CDS asd NC_011900.1 909147 910223 D catalyzes the formation of 4-aspartyl phosphate from aspartate 4-semialdehyde; aspartate-semialdehyde dehydrogenase 909147..910223 Streptococcus pneumoniae ATCC 700669 7327636 YP_002510921.1 CDS dapA NC_011900.1 910279 911214 D catalyzes the formation of dihydrodipicolinate from L-aspartate 4-semialdehyde and pyruvate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate synthase 910279..911214 Streptococcus pneumoniae ATCC 700669 7328666 YP_002510922.1 CDS trmE NC_011900.1 911261 912634 R in Escherichia coli this protein is involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2-thiouridine, which is found in the wobble position of some tRNAs and affects ribosomal frameshifting; shows potassium-dependent dimerization and GTP hydrolysis; also involved in regulation of glutamate-dependent acid resistance and activation of gadE; tRNA modification GTPase TrmE complement(911261..912634) Streptococcus pneumoniae ATCC 700669 7329221 YP_002510923.1 CDS SPN23F_09410 NC_011900.1 912770 912952 R 4-OT; member of subfamily 5; forms a dimer; the function in the Escherichia coli cell is unknown; 4-oxalocrotonate tautomerase complement(912770..912952) Streptococcus pneumoniae ATCC 700669 7327586 YP_002510924.1 CDS tdk NC_011900.1 913075 913665 D catalyzes the formation of thymidine 5'-phosphate from thymidine; thymidine kinase 913075..913665 Streptococcus pneumoniae ATCC 700669 7328933 YP_002510925.1 CDS prfA NC_011900.1 913662 914741 D recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2; peptide chain release factor 1 913662..914741 Streptococcus pneumoniae ATCC 700669 7329163 YP_002510926.1 CDS SPN23F_09440 NC_011900.1 914741 915580 D methyltransferase 914741..915580 Streptococcus pneumoniae ATCC 700669 7327872 YP_002510927.1 CDS SPN23F_09450 NC_011900.1 915564 916166 D hypothetical protein 915564..916166 Streptococcus pneumoniae ATCC 700669 7328934 YP_002510928.1 CDS SPN23F_09460 NC_011900.1 916168 916599 D GNAT family acetyltransferase 916168..916599 Streptococcus pneumoniae ATCC 700669 7328935 YP_002510929.1 CDS glyA NC_011900.1 916661 917917 D catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate; serine hydroxymethyltransferase 916661..917917 Streptococcus pneumoniae ATCC 700669 7328936 YP_002510930.1 CDS SPN23F_09480 NC_011900.1 917925 918899 D hypothetical protein 917925..918899 Streptococcus pneumoniae ATCC 700669 7328613 YP_002510931.1 CDS SPN23F_09490 NC_011900.1 918899 919513 D hypothetical protein 918899..919513 Streptococcus pneumoniae ATCC 700669 7328937 YP_002510932.1 CDS SPN23F_09500 NC_011900.1 919587 920561 D hypothetical protein 919587..920561 Streptococcus pneumoniae ATCC 700669 7328938 YP_002510933.1 CDS SPN23F_09510 NC_011900.1 920635 922266 D RNA methyltransferase 920635..922266 Streptococcus pneumoniae ATCC 700669 7328939 YP_002510934.1 CDS SPN23F_09511 NC_011900.1 922465 922758 D hypothetical protein 922465..922758 Streptococcus pneumoniae ATCC 700669 7328940 YP_002510935.1 CDS SPN23F_09520 NC_011900.1 923004 923222 D regulatory protein 923004..923222 Streptococcus pneumoniae ATCC 700669 7328941 YP_002510936.1 CDS SPN23F_09530 NC_011900.1 923615 924640 D iron-siderophore binding lipoprotein 923615..924640 Streptococcus pneumoniae ATCC 700669 7328942 YP_002510937.1 CDS SPN23F_09540 NC_011900.1 924630 925637 D ferric siderophore ABC transporter permease 924630..925637 Streptococcus pneumoniae ATCC 700669 7328863 YP_002510938.1 CDS SPN23F_09550 NC_011900.1 925637 926644 D ferric enterobactin transport protein 925637..926644 Streptococcus pneumoniae ATCC 700669 7328943 YP_002510939.1 CDS SPN23F_09560 NC_011900.1 926644 927438 D ferric siderophore ABC transporter ATP-binding protein 926644..927438 Streptococcus pneumoniae ATCC 700669 7328944 YP_002510940.1 CDS SPN23F_09562 NC_011900.1 928006 928215 D hypothetical protein 928006..928215 Streptococcus pneumoniae ATCC 700669 7328946 YP_002510941.1 CDS SPN23F_09570 NC_011900.1 928340 928495 D hypothetical protein 928340..928495 Streptococcus pneumoniae ATCC 700669 7328947 YP_002510942.1 CDS SPN23F_09571 NC_011900.1 928674 928817 D hypothetical protein 928674..928817 Streptococcus pneumoniae ATCC 700669 7328948 YP_002510943.1 CDS SPN23F_09580 NC_011900.1 929179 929340 D hypothetical protein 929179..929340 Streptococcus pneumoniae ATCC 700669 7328949 YP_002510944.1 CDS SPN23F_09610 NC_011900.1 931379 931945 D hypothetical protein 931379..931945 Streptococcus pneumoniae ATCC 700669 7328951 YP_002510945.1 CDS SPN23F_09620 NC_011900.1 932267 932455 D hypothetical protein 932267..932455 Streptococcus pneumoniae ATCC 700669 7328952 YP_002510946.1 CDS SPN23F_09630 NC_011900.1 932517 933332 D hypothetical protein 932517..933332 Streptococcus pneumoniae ATCC 700669 7328953 YP_002510947.1 CDS SPN23F_09640 NC_011900.1 933332 934186 D hydrolase 933332..934186 Streptococcus pneumoniae ATCC 700669 7328954 YP_002510948.1 CDS SPN23F_09650 NC_011900.1 934298 935182 D hypothetical protein 934298..935182 Streptococcus pneumoniae ATCC 700669 7328955 YP_002510949.1 CDS SPN23F_09660 NC_011900.1 935345 937084 D alpha-amylase 935345..937084 Streptococcus pneumoniae ATCC 700669 7328956 YP_002510950.1 CDS SPN23F_09670 NC_011900.1 937170 937487 D hypothetical protein 937170..937487 Streptococcus pneumoniae ATCC 700669 7328957 YP_002510951.1 CDS SPN23F_09700 NC_011900.1 938259 938735 D epsilon antitoxin 938259..938735 Streptococcus pneumoniae ATCC 700669 7328958 YP_002510952.1 CDS SPN23F_09710 NC_011900.1 938735 939496 D zeta-toxin 938735..939496 Streptococcus pneumoniae ATCC 700669 7328959 YP_002510953.1 CDS SPN23F_09731 NC_011900.1 941158 941352 D hypothetical protein 941158..941352 Streptococcus pneumoniae ATCC 700669 7328961 YP_002510954.1 CDS SPN23F_09740 NC_011900.1 941512 941871 D Tn5252, orf 10 protein 941512..941871 Streptococcus pneumoniae ATCC 700669 7328962 YP_002510955.1 CDS SPN23F_09750 NC_011900.1 941881 942210 D Tn5252, orf 9 protein 941881..942210 Streptococcus pneumoniae ATCC 700669 7328963 YP_002510956.1 CDS SPN23F_09790 NC_011900.1 944159 945010 R regulatory protein complement(944159..945010) Streptococcus pneumoniae ATCC 700669 7328965 YP_002510957.1 CDS SPN23F_09810 NC_011900.1 945774 947897 D lantibiotic export protein 945774..947897 Streptococcus pneumoniae ATCC 700669 7328968 YP_002510958.1 CDS SPN23F_09820 NC_011900.1 947910 948080 D hypothetical protein 947910..948080 Streptococcus pneumoniae ATCC 700669 7328969 YP_002510959.1 CDS SPN23F_09830 NC_011900.1 948114 948842 D lantibiotic transport ATP-binding protein 948114..948842 Streptococcus pneumoniae ATCC 700669 7328970 YP_002510960.1 CDS SPN23F_09840 NC_011900.1 948835 949572 D hypothetical protein 948835..949572 Streptococcus pneumoniae ATCC 700669 7328971 YP_002510961.1 CDS SPN23F_09850 NC_011900.1 949585 950295 D hypothetical protein 949585..950295 Streptococcus pneumoniae ATCC 700669 7328972 YP_002510962.1 CDS SPN23F_09860 NC_011900.1 950837 951058 D DNA_binding protein 950837..951058 Streptococcus pneumoniae ATCC 700669 7328973 YP_002510963.1 CDS ftsW NC_011900.1 951956 953185 D cell division protein 951956..953185 Streptococcus pneumoniae ATCC 700669 7328975 YP_002510964.1 CDS ppc NC_011900.1 953205 955901 D catalyzes the formation of oxaloacetate from phosphoenolpyruvate; phosphoenolpyruvate carboxylase 953205..955901 Streptococcus pneumoniae ATCC 700669 7328571 YP_002510965.1 CDS SPN23F_09900 NC_011900.1 956314 957318 D ABC transporter substrate-binding protein 956314..957318 Streptococcus pneumoniae ATCC 700669 7329470 YP_002510966.1 CDS SPN23F_09910 NC_011900.1 957387 958253 D ABC transporter permease 957387..958253 Streptococcus pneumoniae ATCC 700669 7328976 YP_002510967.1 CDS SPN23F_09920 NC_011900.1 958250 959008 D ABC transporter ATP-binding protein 958250..959008 Streptococcus pneumoniae ATCC 700669 7328977 YP_002510968.1 CDS dnaG NC_011900.1 959098 960858 D synthesizes RNA primers at the replication forks; DNA primase 959098..960858 Streptococcus pneumoniae ATCC 700669 7328978 YP_002510969.1 CDS rpoD NC_011900.1 960861 961970 D sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; primary sigma factor of bacterium; RNA polymerase sigma factor RpoD 960861..961970 Streptococcus pneumoniae ATCC 700669 7329241 YP_002510970.1 CDS SPN23F_09950 NC_011900.1 961984 962313 D hypothetical protein 961984..962313 Streptococcus pneumoniae ATCC 700669 7329106 YP_002510971.1 CDS SPN23F_09960 NC_011900.1 962428 963471 D glycosyltransferase 962428..963471 Streptococcus pneumoniae ATCC 700669 7328979 YP_002510972.1 CDS SPN23F_09970 NC_011900.1 963487 964812 D glycosyltransferase 963487..964812 Streptococcus pneumoniae ATCC 700669 7328980 YP_002510973.1 CDS SPN23F_09980 NC_011900.1 964843 965019 D phage shock protein 964843..965019 Streptococcus pneumoniae ATCC 700669 7328981 YP_002510974.1 CDS SPN23F_09990 NC_011900.1 965078 965212 D hypothetical protein 965078..965212 Streptococcus pneumoniae ATCC 700669 7328982 YP_002510975.1 CDS obgE NC_011900.1 965282 966586 D essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication; GTPase ObgE 965282..966586 Streptococcus pneumoniae ATCC 700669 7328983 YP_002510976.1 CDS SPN23F_10010 NC_011900.1 966596 966754 D hypothetical protein 966596..966754 Streptococcus pneumoniae ATCC 700669 7328984 YP_002510977.1 CDS murZ NC_011900.1 967841 969100 D adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active; UDP-N-acetylglucosamine 1-carboxyvinyltransferase 967841..969100 Streptococcus pneumoniae ATCC 700669 7328985 YP_002510978.1 CDS SPN23F_10030 NC_011900.1 969116 969667 D GNAT family acetyltransferase 969116..969667 Streptococcus pneumoniae ATCC 700669 7328400 YP_002510979.1 CDS SPN23F_10040 NC_011900.1 969660 970937 D DNA-binding protein 969660..970937 Streptococcus pneumoniae ATCC 700669 7328986 YP_002510980.1 CDS SPN23F_10050 NC_011900.1 970953 971813 D catalyzes the removal of N-terminal amino acids from peptides and arylamides; methionine aminopeptidase 970953..971813 Streptococcus pneumoniae ATCC 700669 7328987 YP_002510981.1 CDS pcrA NC_011900.1 973187 975478 D ATP-dependent DNA helicase 973187..975478 Streptococcus pneumoniae ATCC 700669 7328990 YP_002510982.1 CDS radC NC_011900.1 975521 976201 D Involved in DNA double-strand break repair and recombination. Promotes the annealing of complementary single-stranded DNA and by simulation of RAD51 recombinase; DNA repair protein RadC 975521..976201 Streptococcus pneumoniae ATCC 700669 7328461 YP_002510983.1 CDS SPN23F_10100 NC_011900.1 976198 976887 R peptidase complement(976198..976887) Streptococcus pneumoniae ATCC 700669 7327440 YP_002510984.1 CDS rex NC_011900.1 976905 977546 R modulates transcription in response to the NADH/NAD(+) redox state; redox-sensing transcriptional repressor Rex complement(976905..977546) Streptococcus pneumoniae ATCC 700669 7328991 YP_002510985.1 CDS SPN23F_10120 NC_011900.1 977629 977844 R hypothetical protein complement(977629..977844) Streptococcus pneumoniae ATCC 700669 7327451 YP_002510986.1 CDS SPN23F_10130 NC_011900.1 977852 978199 R hypothetical protein complement(977852..978199) Streptococcus pneumoniae ATCC 700669 7328992 YP_002510987.1 CDS SPN23F_10140 NC_011900.1 978204 979319 R cysteine desulfurase complement(978204..979319) Streptococcus pneumoniae ATCC 700669 7328993 YP_002510988.1 CDS prsA2 NC_011900.1 979329 980288 R catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP; ribose-phosphate pyrophosphokinase complement(979329..980288) Streptococcus pneumoniae ATCC 700669 7328994 YP_002510989.1 CDS SPN23F_10160 NC_011900.1 980401 980970 R adenylate cyclase family protein complement(980401..980970) Streptococcus pneumoniae ATCC 700669 7327882 YP_002510990.1 CDS SPN23F_10170 NC_011900.1 981098 981769 D hypothetical protein 981098..981769 Streptococcus pneumoniae ATCC 700669 7328995 YP_002510991.1 CDS ppnK NC_011900.1 981753 982571 D catalyzes the phosphorylation of NAD to NADP; inorganic polyphosphate/ATP-NAD kinase 981753..982571 Streptococcus pneumoniae ATCC 700669 7328996 YP_002510992.1 CDS SPN23F_10190 NC_011900.1 982568 983464 D RNA pseudouridylate synthase 982568..983464 Streptococcus pneumoniae ATCC 700669 7327871 YP_002510993.1 CDS eutD NC_011900.1 983508 984482 D in Salmonella this enzyme is required for ethanolamine catabolism; has higher affinity for CoA than Pta; phosphotransacetylase 983508..984482 Streptococcus pneumoniae ATCC 700669 7328997 YP_002510994.1 CDS SPN23F_10240 NC_011900.1 986251 986550 R hypothetical protein complement(986251..986550) Streptococcus pneumoniae ATCC 700669 7328999 YP_002510995.1 CDS SPN23F_10250 NC_011900.1 986952 987656 D hypothetical protein 986952..987656 Streptococcus pneumoniae ATCC 700669 7329000 YP_002510996.1 CDS rplU NC_011900.1 987838 988152 D 50S ribosomal protein L21 987838..988152 Streptococcus pneumoniae ATCC 700669 7329001 YP_002510997.1 CDS SPN23F_10270 NC_011900.1 988168 988512 D hypothetical protein 988168..988512 Streptococcus pneumoniae ATCC 700669 7327488 YP_002510998.1 CDS rpmA NC_011900.1 988529 988822 D involved in the peptidyltransferase reaction during translation; 50S ribosomal protein L27 988529..988822 Streptococcus pneumoniae ATCC 700669 7329002 YP_002510999.1 CDS ribC NC_011900.1 989775 990692 D catalyzes the formation of FMN from riboflavin and the formation of FAD from FMN; in Bacillus the ribC gene has both flavokinase and FAD synthetase activities; bifunctional riboflavin kinase/FMN adenylyltransferase 989775..990692 Streptococcus pneumoniae ATCC 700669 7327492 YP_002511000.1 CDS SPN23F_10320 NC_011900.1 990785 991633 R hypothetical protein complement(990785..991633) Streptococcus pneumoniae ATCC 700669 7327453 YP_002511001.1 CDS SPN23F_10330 NC_011900.1 991775 992614 D hypothetical protein 991775..992614 Streptococcus pneumoniae ATCC 700669 7329003 YP_002511002.1 CDS hlpA NC_011900.1 992721 992996 D DNA-binding protein HU 992721..992996 Streptococcus pneumoniae ATCC 700669 7329004 YP_002511003.1 CDS SPN23F_10350 NC_011900.1 993426 995327 D ABC transporter ATP-binding protein 993426..995327 Streptococcus pneumoniae ATCC 700669 7328071 YP_002511004.1 CDS SPN23F_10360 NC_011900.1 995330 996193 D DNA-binding protein 995330..996193 Streptococcus pneumoniae ATCC 700669 7329005 YP_002511005.1 CDS SPN23F_10370 NC_011900.1 996273 997451 D membrane transport protein 996273..997451 Streptococcus pneumoniae ATCC 700669 7329006 YP_002511006.1 CDS ligA NC_011900.1 997544 999502 D this protein catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction; essential for DNA replication and repair of damaged DNA; similar to ligase LigB; NAD-dependent DNA ligase LigA 997544..999502 Streptococcus pneumoniae ATCC 700669 7329007 YP_002511007.1 CDS SPN23F_10390 NC_011900.1 999614 1001893 D pullulanase 999614..1001893 Streptococcus pneumoniae ATCC 700669 7328109 YP_002511008.1 CDS gapN NC_011900.1 1002438 1003862 D NADP-dependent glyceraldehyde-3-phosphate dehydrogenase 1002438..1003862 Streptococcus pneumoniae ATCC 700669 7329008 YP_002511009.1 CDS glgB NC_011900.1 1004345 1006273 D catalyzes the transfer of a segment of a 1,4-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain; glycogen branching enzyme 1004345..1006273 Streptococcus pneumoniae ATCC 700669 7328585 YP_002511010.1 CDS glgC NC_011900.1 1006263 1007405 D catalyzes the formation of ADP-glucose and diphosphate from ATP and alpha-D-glucose 1-phosphate; glucose-1-phosphate adenylyltransferase 1006263..1007405 Streptococcus pneumoniae ATCC 700669 7328597 YP_002511011.1 CDS SPN23F_10430 NC_011900.1 1007395 1008534 D glycogen biosynthesis protein 1007395..1008534 Streptococcus pneumoniae ATCC 700669 7328598 YP_002511012.1 CDS glgA NC_011900.1 1008531 1009964 D catalyzes the formation of alpha-1,4-glucan chains from ADP-glucose; glycogen synthase 1008531..1009964 Streptococcus pneumoniae ATCC 700669 7329009 YP_002511013.1 CDS SPN23F_10470 NC_011900.1 1010677 1011480 D May be a pseudogene; truncated by an internal deletion relative to some orthologues; glycerate kinase-family protein 1010677..1011480 Streptococcus pneumoniae ATCC 700669 7329010 YP_002511014.1 CDS SPN23F_10480 NC_011900.1 1011477 1011923 R hypothetical protein complement(1011477..1011923) Streptococcus pneumoniae ATCC 700669 7329012 YP_002511015.1 CDS eno NC_011900.1 1012087 1013391 D enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis; phosphopyruvate hydratase 1012087..1013391 Streptococcus pneumoniae ATCC 700669 7329013 YP_002511016.1 CDS addB NC_011900.1 1015234 1018509 D ATP-dependent exonuclease subunit B 1015234..1018509 Streptococcus pneumoniae ATCC 700669 7329015 YP_002511017.1 CDS addA NC_011900.1 1018506 1022156 D ATP-dependent exonuclease subunit A 1018506..1022156 Streptococcus pneumoniae ATCC 700669 7328635 YP_002511018.1 CDS SPN23F_10570 NC_011900.1 1022371 1023549 D hypothetical protein 1022371..1023549 Streptococcus pneumoniae ATCC 700669 7328634 YP_002511019.1 CDS zmpA NC_011900.1 1023758 1030237 D IgA-protease 1023758..1030237 Streptococcus pneumoniae ATCC 700669 7329016 YP_002511020.1 CDS zmpD NC_011900.1 1030281 1035494 D Zinc metalloprotease ZmpD 1030281..1035494 Streptococcus pneumoniae ATCC 700669 7329451 YP_002511021.1 CDS rbgA NC_011900.1 1035748 1036599 D essential GTPase; functions in ribosome assembly; binds a unique part of the 23S rRNA; interacts with ribosomal protein L25(Ctc); ribosomal biogenesis GTPase 1035748..1036599 Streptococcus pneumoniae ATCC 700669 7329453 YP_002511022.1 CDS rnhB NC_011900.1 1036586 1037365 D RNH2; RNase HII; binds manganese; endonuclease which specifically degrades the RNA of RNA-DNA hybrids; ribonuclease HII 1036586..1037365 Streptococcus pneumoniae ATCC 700669 7329017 YP_002511023.1 CDS SPN23F_10620 NC_011900.1 1037381 1038931 D voltage gated chloride channel family protein 1037381..1038931 Streptococcus pneumoniae ATCC 700669 7327464 YP_002511024.1 CDS xerS NC_011900.1 1039515 1040585 D site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; cell division protein FtsK may regulate the XerS; site-specific tyrosine recombinase XerS 1039515..1040585 Streptococcus pneumoniae ATCC 700669 7329018 YP_002511025.1 CDS SPN23F_10640 NC_011900.1 1040650 1041639 R lipoate-protein ligase A complement(1040650..1041639) Streptococcus pneumoniae ATCC 700669 7329019 YP_002511026.1 CDS acoL NC_011900.1 1041703 1043388 R dihydrolipoamide dehydrogenase complement(1041703..1043388) Streptococcus pneumoniae ATCC 700669 7329020 YP_002511027.1 CDS acoC NC_011900.1 1043452 1044495 R unlike PdhC proteins from other organisms, some Mycoplasma lack an N-terminal lipoyl domain; in Mycoplasma hyopneumonia the PdhD proteins contains the lipoyl domain; dihydrolipoamide acetyltransferase complement(1043452..1044495) Streptococcus pneumoniae ATCC 700669 7328630 YP_002511028.1 CDS pdhB NC_011900.1 1044713 1045705 R pyruvate dehydrogenase E1 component,beta subunit complement(1044713..1045705) Streptococcus pneumoniae ATCC 700669 7328629 YP_002511029.1 CDS pdhA NC_011900.1 1045721 1046689 R pyruvate dehydrogenase E1 component,alpha subunit complement(1045721..1046689) Streptococcus pneumoniae ATCC 700669 7327821 YP_002511030.1 CDS SPN23F_10690 NC_011900.1 1046843 1048204 R multidrug resistance protein complement(1046843..1048204) Streptococcus pneumoniae ATCC 700669 7327820 YP_002511031.1 CDS pyrC NC_011900.1 1048489 1049757 R catalyzes the formation of N-carbamoyl-L-aspartate from (S)-dihydroorotate in pyrimidine biosynthesis; dihydroorotase complement(1048489..1049757) Streptococcus pneumoniae ATCC 700669 7329021 YP_002511032.1 CDS mutX NC_011900.1 1049770 1050234 R mutator MutX protein (7,8-dihydro-8-oxoguanine-triphosphatase) complement(1049770..1050234) Streptococcus pneumoniae ATCC 700669 7327429 YP_002511033.1 CDS ung NC_011900.1 1050244 1050897 R Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine; uracil-DNA glycosylase complement(1050244..1050897) Streptococcus pneumoniae ATCC 700669 7328404 YP_002511034.1 CDS SPN23F_10730 NC_011900.1 1051033 1051680 R hypothetical protein complement(1051033..1051680) Streptococcus pneumoniae ATCC 700669 7329420 YP_002511035.1 CDS SPN23F_10740 NC_011900.1 1051694 1052407 R haloacid dehalogenase-like hydrolase complement(1051694..1052407) Streptococcus pneumoniae ATCC 700669 7329673 YP_002511036.1 CDS SPN23F_10750 NC_011900.1 1052866 1053240 R phosphotransferase mannnose-specific family component IIA complement(1052866..1053240) Streptococcus pneumoniae ATCC 700669 7327661 YP_002511037.1 CDS phpA NC_011900.1 1053659 1056181 R streptococcal histidine triad protein PhpA complement(1053659..1056181) Streptococcus pneumoniae ATCC 700669 7327662 YP_002511038.1 CDS pstI NC_011900.1 1056435 1058168 R phosphoenolpyruvate-protein phosphotransferase complement(1056435..1058168) Streptococcus pneumoniae ATCC 700669 7327847 YP_002511039.1 CDS ptsH NC_011900.1 1058174 1058437 R phosphocarrier protein HPr complement(1058174..1058437) Streptococcus pneumoniae ATCC 700669 7327888 YP_002511040.1 CDS nrdH NC_011900.1 1058788 1059006 D glutaredoxin-like protein 1058788..1059006 Streptococcus pneumoniae ATCC 700669 7327893 YP_002511041.1 CDS SPN23F_10810 NC_011900.1 1059087 1061246 D Catalyzes the rate-limiting step in dNTP synthesis; ribonucleotide-diphosphate reductase subunit alpha 1059087..1061246 Streptococcus pneumoniae ATCC 700669 7328424 YP_002511042.1 CDS nrdF NC_011900.1 1061434 1062396 D B2 or R2 protein; type 1b enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdE; ribonucleotide-diphosphate reductase subunit beta 1061434..1062396 Streptococcus pneumoniae ATCC 700669 7327663 YP_002511043.1 CDS lacR1 NC_011900.1 1062684 1063445 D lactose phosphotransferase system repressor 1 1062684..1063445 Streptococcus pneumoniae ATCC 700669 7327664 YP_002511044.1 CDS lacG2 NC_011900.1 1063808 1065214 R catalyzes the formation of 6-phospho-galactose from a 6-phospho-beta-galactoside; 6-phospho-beta-galactosidase complement(1063808..1065214) Streptococcus pneumoniae ATCC 700669 7328098 YP_002511045.1 CDS lacE2 NC_011900.1 1065429 1067123 R lactose-specific phosphotransferase system (PTS), IIBC component 2 complement(1065429..1067123) Streptococcus pneumoniae ATCC 700669 7328097 YP_002511046.1 CDS lacF NC_011900.1 1067125 1067442 R PTS system, lactose-specific IIA component complement(1067125..1067442) Streptococcus pneumoniae ATCC 700669 7328095 YP_002511047.1 CDS lacT2 NC_011900.1 1067478 1068314 R transcription antiterminator LacT 2 complement(1067478..1068314) Streptococcus pneumoniae ATCC 700669 7328096 YP_002511048.1 CDS lacD2 NC_011900.1 1068548 1069528 R catalyzes the reversible reaction of dihydroxyacetone phosphate with glyceraldehyde 3-phosphate to produce tagatose 1,6-bisphosphate; in Streptococcus pyogenes there are two paralogs of tagatose-bisphosphate aldolase, encoded by lacD1 and lacD2; expression of lacD1 is highly regulated by environmental conditions while lacD2 specializes in an efficient utilization of carbohydrate sources; tagatose 1,6-diphosphate aldolase complement(1068548..1069528) Streptococcus pneumoniae ATCC 700669 7328099 YP_002511049.1 CDS lacC2 NC_011900.1 1069530 1070459 R catalyzes the formation of tagatose 1,6-bisphosphate from tagatose 6-phosphate and ATP; tagatose-6-phosphate kinase complement(1069530..1070459) Streptococcus pneumoniae ATCC 700669 7328094 YP_002511050.1 CDS lacB1 NC_011900.1 1070470 1070985 R catalyzes the interconversion of galactose 6-phosphate to tagatose 6-phosphate; galactose-6-phosphate isomerase subunit LacB complement(1070470..1070985) Streptococcus pneumoniae ATCC 700669 7328093 YP_002511051.1 CDS lacA NC_011900.1 1071016 1071441 R catalyzes the interconversion of galactose 6-phosphate to tagatose 6-phosphate; tagatose pathway for galactose utilization; galactose-6-phosphate isomerase subunit LacA complement(1071016..1071441) Streptococcus pneumoniae ATCC 700669 7328092 YP_002511052.1 CDS SPN23F_10980 NC_011900.1 1073263 1073739 R sugar phosphotransferase system (PTS), IIA component complement(1073263..1073739) Streptococcus pneumoniae ATCC 700669 7327667 YP_002511053.1 CDS lepA NC_011900.1 1074152 1075975 R binds to the ribosome on the universally-conserved alpha-sarcin loop; GTP-binding protein LepA complement(1074152..1075975) Streptococcus pneumoniae ATCC 700669 7327668 YP_002511054.1 CDS SPN23F_11010 NC_011900.1 1076054 1076782 R Calcineurin-like phosphoesterase complement(1076054..1076782) Streptococcus pneumoniae ATCC 700669 7328102 YP_002511055.1 CDS recN NC_011900.1 1076784 1078451 R DNA repair protein complement(1076784..1078451) Streptococcus pneumoniae ATCC 700669 7327669 YP_002511056.1 CDS SPN23F_11030 NC_011900.1 1078458 1078889 R repressor protein complement(1078458..1078889) Streptococcus pneumoniae ATCC 700669 7327445 YP_002511057.1 CDS SPN23F_11040 NC_011900.1 1078882 1079697 R hemolysin-like protein complement(1078882..1079697) Streptococcus pneumoniae ATCC 700669 7327670 YP_002511058.1 CDS fps NC_011900.1 1079690 1080565 R geranyltranstransferase complement(1079690..1080565) Streptococcus pneumoniae ATCC 700669 7327671 YP_002511059.1 CDS xseB NC_011900.1 1080562 1080774 R catalyzes the bidirectional exonucleolytic cleavage of DNA; exodeoxyribonuclease VII small subunit complement(1080562..1080774) Streptococcus pneumoniae ATCC 700669 7328563 YP_002511060.1 CDS xseA NC_011900.1 1080752 1082092 R bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides; exodeoxyribonuclease VII large subunit complement(1080752..1082092) Streptococcus pneumoniae ATCC 700669 7329450 YP_002511061.1 CDS udk NC_011900.1 1082220 1082858 R functions in pyrimidine salvage; pyrimidine ribonucleoside kinase; phosphorylates nucleosides or dinucleosides to make UMP or CMP using ATP or GTP as the donor; uridine kinase complement(1082220..1082858) Streptococcus pneumoniae ATCC 700669 7329449 YP_002511062.1 CDS SPN23F_11090 NC_011900.1 1082966 1083268 R bacteriocin immunity protein complement(1082966..1083268) Streptococcus pneumoniae ATCC 700669 7327659 YP_002511063.1 CDS truB NC_011900.1 1083509 1084387 R catalyzes isomerization of specific uridines in RNA to pseudouridine; responsible for residues in T loops of many tRNAs; tRNA pseudouridine synthase B complement(1083509..1084387) Streptococcus pneumoniae ATCC 700669 7327672 YP_002511064.1 CDS SPN23F_11110 NC_011900.1 1084397 1085671 R hypothetical protein complement(1084397..1085671) Streptococcus pneumoniae ATCC 700669 7327654 YP_002511065.1 CDS SPN23F_11140 NC_011900.1 1087174 1087971 R formate/nitrate transport protein complement(1087174..1087971) Streptococcus pneumoniae ATCC 700669 7327674 YP_002511066.1 CDS srtA NC_011900.1 1088215 1088958 R sortase SrtA complement(1088215..1088958) Streptococcus pneumoniae ATCC 700669 7327675 YP_002511067.1 CDS gyrA NC_011900.1 1088958 1091426 R negatively supercoils closed circular double-stranded DNA; DNA gyrase subunit A complement(1088958..1091426) Streptococcus pneumoniae ATCC 700669 7329153 YP_002511068.1 CDS ldh NC_011900.1 1091620 1092606 D Converts (S)-lactate and NAD(+) to pyruvate and NADH; L-lactate dehydrogenase 1091620..1092606 Streptococcus pneumoniae ATCC 700669 7328065 YP_002511069.1 CDS SPN23F_11180 NC_011900.1 1092854 1093627 R ion channel transport protein complement(1092854..1093627) Streptococcus pneumoniae ATCC 700669 7328101 YP_002511070.1 CDS SPN23F_11190 NC_011900.1 1093674 1093928 R plasmid addiction system, toxin protein complement(1093674..1093928) Streptococcus pneumoniae ATCC 700669 7327676 YP_002511071.1 CDS SPN23F_11200 NC_011900.1 1093930 1094172 R hypothetical protein complement(1093930..1094172) Streptococcus pneumoniae ATCC 700669 7327677 YP_002511072.1 CDS vicX NC_011900.1 1094263 1095072 R metallo-beta-lactamase superfamily protein complement(1094263..1095072) Streptococcus pneumoniae ATCC 700669 7327678 YP_002511073.1 CDS vicK NC_011900.1 1095074 1096423 R sensor histidine kinase complement(1095074..1096423) Streptococcus pneumoniae ATCC 700669 7329431 YP_002511074.1 CDS vicR NC_011900.1 1096416 1097120 R response regulator protein complement(1096416..1097120) Streptococcus pneumoniae ATCC 700669 7329429 YP_002511075.1 CDS mutY NC_011900.1 1097175 1098350 R A/G-specific adenine glycosylase complement(1097175..1098350) Streptococcus pneumoniae ATCC 700669 7329430 YP_002511076.1 CDS fhs1 NC_011900.1 1098678 1100348 R catalyzes the formation of 10-formyltetrahydrofolate from formate and tetrahydrofolate; formate--tetrahydrofolate ligase complement(1098678..1100348) Streptococcus pneumoniae ATCC 700669 7328405 YP_002511077.1 CDS dpfB NC_011900.1 1100578 1101267 D phosphopantothenate--cysteine ligase 1100578..1101267 Streptococcus pneumoniae ATCC 700669 7328554 YP_002511078.1 CDS coaC NC_011900.1 1101279 1101830 D decarboxylates 4-phosphopantothenoylcysteine to form 4'-phosphopantotheine.; phosphopantothenoylcysteine decarboxylase 1101279..1101830 Streptococcus pneumoniae ATCC 700669 7329247 YP_002511079.1 CDS SPN23F_11280 NC_011900.1 1101814 1102377 D hypothetical protein 1101814..1102377 Streptococcus pneumoniae ATCC 700669 7329202 YP_002511080.1 CDS SPN23F_11290 NC_011900.1 1102659 1103186 D hypothetical protein 1102659..1103186 Streptococcus pneumoniae ATCC 700669 7327679 YP_002511081.1 CDS SPN23F_11300 NC_011900.1 1103198 1103713 D small-molecule-binding protein 1103198..1103713 Streptococcus pneumoniae ATCC 700669 7327680 YP_002511082.1 CDS SPN23F_11310 NC_011900.1 1103710 1104177 R MutT/NUDIX hydrolase family protein complement(1103710..1104177) Streptococcus pneumoniae ATCC 700669 7327681 YP_002511083.1 CDS SPN23F_11320 NC_011900.1 1104251 1104739 R GNAT family acetyltransferase complement(1104251..1104739) Streptococcus pneumoniae ATCC 700669 7327682 YP_002511084.1 CDS SPN23F_11330 NC_011900.1 1104705 1105268 R hypothetical protein complement(1104705..1105268) Streptococcus pneumoniae ATCC 700669 7327683 YP_002511085.1 CDS uvrB NC_011900.1 1105278 1107266 R The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion; excinuclease ABC subunit B complement(1105278..1107266) Streptococcus pneumoniae ATCC 700669 7327684 YP_002511086.1 CDS SPN23F_11350 NC_011900.1 1107343 1108296 R CAAX amino terminal protease family protein complement(1107343..1108296) Streptococcus pneumoniae ATCC 700669 7329424 YP_002511087.1 CDS SPN23F_11360 NC_011900.1 1108469 1110634 D glutamine ABC transporter,glutamine-binding protein/permease protein 1108469..1110634 Streptococcus pneumoniae ATCC 700669 7327685 YP_002511088.1 CDS glnQ1 NC_011900.1 1110634 1111374 D glutamine ABC transporter ATP-binding protein 1 1110634..1111374 Streptococcus pneumoniae ATCC 700669 7327686 YP_002511089.1 CDS zwf NC_011900.1 1111523 1113010 D catalyzes the formation of D-glucono-1,5-lactone 6-phosphate from D-glucose 6-phosphate; glucose-6-phosphate 1-dehydrogenase 1111523..1113010 Streptococcus pneumoniae ATCC 700669 7328603 YP_002511090.1 CDS ftsY NC_011900.1 1113056 1114345 R signal recognition particle 54 FtsY complement(1113056..1114345) Streptococcus pneumoniae ATCC 700669 7329454 YP_002511091.1 CDS SPN23F_11400 NC_011900.1 1114349 1115167 R haloacid dehalogenase-like hydrolase complement(1114349..1115167) Streptococcus pneumoniae ATCC 700669 7328573 YP_002511092.1 CDS SPN23F_11410 NC_011900.1 1115167 1115961 R haloacid dehalogenase-like hydrolase complement(1115167..1115961) Streptococcus pneumoniae ATCC 700669 7327687 YP_002511093.1 CDS smc NC_011900.1 1115958 1119497 R chromosome partition protein complement(1115958..1119497) Streptococcus pneumoniae ATCC 700669 7327688 YP_002511094.1 CDS rnc NC_011900.1 1119488 1120186 R cytoplasmic enzyme involved in processing rRNA and some mRNAs; substrates typically have dsRNA regions; forms a homodimer; have N-terminal nuclease and C-terminal RNA-binding domains; requires magnesium as preferred ion for activity; ribonuclease III complement(1119488..1120186) Streptococcus pneumoniae ATCC 700669 7329144 YP_002511095.1 CDS SPN23F_11440 NC_011900.1 1120504 1121490 R guanosine 5'-monophosphate oxidoreductase complement(1120504..1121490) Streptococcus pneumoniae ATCC 700669 7327591 YP_002511096.1 CDS SPN23F_11450 NC_011900.1 1121724 1122962 R hypothetical protein complement(1121724..1122962) Streptococcus pneumoniae ATCC 700669 7327689 YP_002511097.1 CDS SPN23F_11460 NC_011900.1 1122949 1124862 R endonuclease complement(1122949..1124862) Streptococcus pneumoniae ATCC 700669 7327690 YP_002511098.1 CDS SPN23F_11500 NC_011900.1 1125809 1126168 R hypothetical protein complement(1125809..1126168) Streptococcus pneumoniae ATCC 700669 7327692 YP_002511099.1 CDS SPN23F_11510 NC_011900.1 1126172 1126441 R hypothetical protein complement(1126172..1126441) Streptococcus pneumoniae ATCC 700669 7327693 YP_002511100.1 CDS leuB NC_011900.1 1126438 1127475 R catalyzes the oxidation of 3-isopropylmalate to 3-carboxy-4-methyl-2-oxopentanoate in leucine biosynthesis; 3-isopropylmalate dehydrogenase complement(1126438..1127475) Streptococcus pneumoniae ATCC 700669 7327694 YP_002511101.1 CDS SPN23F_11550 NC_011900.1 1128600 1129256 R hypothetical protein complement(1128600..1129256) Streptococcus pneumoniae ATCC 700669 7327695 YP_002511102.1 CDS SPN23F_11560 NC_011900.1 1129300 1129932 R CutC family protein complement(1129300..1129932) Streptococcus pneumoniae ATCC 700669 7327696 YP_002511103.1 CDS SPN23F_11570 NC_011900.1 1130025 1130384 R hypothetical protein complement(1130025..1130384) Streptococcus pneumoniae ATCC 700669 7327697 YP_002511104.1 CDS topA NC_011900.1 1130490 1132577 R catalyzes the ATP-dependent breakage of single-stranded DNA followed by passage and rejoining, maintains net negative superhelicity; DNA topoisomerase I complement(1130490..1132577) Streptococcus pneumoniae ATCC 700669 7327698 YP_002511105.1 CDS SPN23F_11590 NC_011900.1 1132744 1133787 R hypothetical protein complement(1132744..1133787) Streptococcus pneumoniae ATCC 700669 7329179 YP_002511106.1 CDS SPN23F_11600 NC_011900.1 1134676 1135524 R SMF family protein complement(1134676..1135524) Streptococcus pneumoniae ATCC 700669 7327699 YP_002511107.1 CDS licC NC_011900.1 1135620 1136309 R CTP:phosphocholine cytidylyltransferase complement(1135620..1136309) Streptococcus pneumoniae ATCC 700669 7327700 YP_002511108.1 CDS SPN23F_11620 NC_011900.1 1136321 1137199 R LicB-family membrane protein complement(1136321..1137199) Streptococcus pneumoniae ATCC 700669 7328107 YP_002511109.1 CDS SPN23F_11630 NC_011900.1 1137189 1138058 R kinase complement(1137189..1138058) Streptococcus pneumoniae ATCC 700669 7327701 YP_002511110.1 CDS SPN23F_11640 NC_011900.1 1138075 1139097 R zinc-binding dehydrogenase complement(1138075..1139097) Streptococcus pneumoniae ATCC 700669 7327702 YP_002511111.1 CDS ispD NC_011900.1 1139102 1139809 R 4-diphosphocytidyl-2C-methyl-D-erythritol synthase; MEP cytidylyltransferase; MCT; catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate; involved in isoprenoid and isopentenyl-PP biosynthesis; forms homodimers; 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase complement(1139102..1139809) Streptococcus pneumoniae ATCC 700669 7327703 YP_002511112.1 CDS SPN23F_11660 NC_011900.1 1140145 1141632 D polysaccharide biosynthesis flippase 1140145..1141632 Streptococcus pneumoniae ATCC 700669 7327704 YP_002511113.1 CDS SPN23F_11670 NC_011900.1 1141642 1142445 D phosphotransferase LicD1 1141642..1142445 Streptococcus pneumoniae ATCC 700669 7327705 YP_002511114.1 CDS SPN23F_11680 NC_011900.1 1142447 1143256 D phosphotransferase LicD2 1142447..1143256 Streptococcus pneumoniae ATCC 700669 7327706 YP_002511115.1 CDS carB NC_011900.1 1143531 1146707 R four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate; CarB is responsible for the amidotransferase activity; carbamoyl phosphate synthase large subunit complement(1143531..1146707) Streptococcus pneumoniae ATCC 700669 7327707 YP_002511116.1 CDS carA NC_011900.1 1147019 1148098 R catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers; carbamoyl phosphate synthase small subunit complement(1147019..1148098) Streptococcus pneumoniae ATCC 700669 7328701 YP_002511117.1 CDS pyrB NC_011900.1 1148148 1149071 R catalyzes the transfer of the carbamoyl moiety from carbamoyl phosphate to L- aspartate in pyrimidine biosynthesis; aspartate carbamoyltransferase catalytic subunit complement(1148148..1149071) Streptococcus pneumoniae ATCC 700669 7328700 YP_002511118.1 CDS pyrR NC_011900.1 1149090 1149611 R regulates pyrimidine biosynthesis by binding to the mRNA of the pyr genes, also has been shown to have uracil phosphoribosyltransferase activity; bifunctional pyrimidine regulatory protein PyrR uracil phosphoribosyltransferase complement(1149090..1149611) Streptococcus pneumoniae ATCC 700669 7327428 YP_002511119.1 CDS nth NC_011900.1 1149846 1150451 R endonuclease III complement(1149846..1150451) Streptococcus pneumoniae ATCC 700669 7327438 YP_002511120.1 CDS SPN23F_11740 NC_011900.1 1150451 1150993 R hypothetical protein complement(1150451..1150993) Streptococcus pneumoniae ATCC 700669 7328425 YP_002511121.1 CDS SPN23F_11760 NC_011900.1 1151727 1152680 D IS1239 transposase 1151727..1152680 Streptococcus pneumoniae ATCC 700669 7327709 YP_002511122.1 CDS SPN23F_11770 NC_011900.1 1152995 1154521 D ABC transporter ATP-binding protein 1152995..1154521 Streptococcus pneumoniae ATCC 700669 7327710 YP_002511123.1 CDS htpX NC_011900.1 1154670 1155569 R metalloprotease; heat shock protein HtpX complement(1154670..1155569) Streptococcus pneumoniae ATCC 700669 7327711 YP_002511124.1 CDS SPN23F_11790 NC_011900.1 1155571 1156131 R LemA family protein complement(1155571..1156131) Streptococcus pneumoniae ATCC 700669 7328077 YP_002511125.1 CDS gidB NC_011900.1 1156225 1156938 D glucose-inhibited division protein B; SAM-dependent methyltransferase; methylates the N7 position of guanosine in position 527 of 16S rRNA; 16S rRNA methyltransferase GidB 1156225..1156938 Streptococcus pneumoniae ATCC 700669 7327712 YP_002511126.1 CDS pyrP NC_011900.1 1157290 1158573 D uracil permease 1157290..1158573 Streptococcus pneumoniae ATCC 700669 7328593 YP_002511127.1 CDS ffh NC_011900.1 1158768 1160339 R signal recognition particle protein complement(1158768..1160339) Streptococcus pneumoniae ATCC 700669 7327437 YP_002511128.1 CDS SPN23F_11830 NC_011900.1 1160351 1160683 R DNA-binding protein complement(1160351..1160683) Streptococcus pneumoniae ATCC 700669 7328553 YP_002511129.1 CDS SPN23F_11840 NC_011900.1 1160774 1161151 R hypothetical protein complement(1160774..1161151) Streptococcus pneumoniae ATCC 700669 7327713 YP_002511130.1 CDS SPN23F_11850 NC_011900.1 1161223 1162527 D phosphohydrolase 1161223..1162527 Streptococcus pneumoniae ATCC 700669 7327714 YP_002511131.1 CDS SPN23F_11860 NC_011900.1 1162540 1163346 D haloacid dehalogenase-like hydrolase 1162540..1163346 Streptococcus pneumoniae ATCC 700669 7327715 YP_002511132.1 CDS rplS NC_011900.1 1163514 1163861 R this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site; 50S ribosomal protein L19 complement(1163514..1163861) Streptococcus pneumoniae ATCC 700669 7327592 YP_002511133.1 CDS SPN23F_11880 NC_011900.1 1163980 1164309 R may be involved in chromosome condensation; overexpression in Escherichia coli protects against decondensation by camphor; overexpressing the protein results in an increase in supercoiling; camphor resistance protein CrcB complement(1163980..1164309) Streptococcus pneumoniae ATCC 700669 7327486 YP_002511134.1 CDS SPN23F_11890 NC_011900.1 1164303 1164677 R may be involved in chromosome condensation; overexpression in Escherichia coli protects against decondensation by camphor; overexpressing the protein results in an increase in supercoiling; camphor resistance protein CrcB complement(1164303..1164677) Streptococcus pneumoniae ATCC 700669 7327717 YP_002511135.1 CDS SPN23F_11900 NC_011900.1 1164674 1164940 R hypothetical protein complement(1164674..1164940) Streptococcus pneumoniae ATCC 700669 7327718 YP_002511136.1 CDS SPN23F_11910 NC_011900.1 1165056 1165499 R An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group; flavodoxin complement(1165056..1165499) Streptococcus pneumoniae ATCC 700669 7327719 YP_002511137.1 CDS SPN23F_11920 NC_011900.1 1165603 1166538 D hypothetical protein 1165603..1166538 Streptococcus pneumoniae ATCC 700669 7327720 YP_002511138.1 CDS rpmE2 NC_011900.1 1166634 1166876 D RpmE2; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster do not have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome; 50S ribosomal protein L31 type B 1166634..1166876 Streptococcus pneumoniae ATCC 700669 7327721 YP_002511139.1 CDS gdh NC_011900.1 1168236 1169582 D converts 2-oxoglutarate to glutamate; in Escherichia coli this enzyme plays a role in glutamate synthesis when the cell is under energy restriction; uses NADPH; forms a homohexamer; glutamate dehydrogenase 1168236..1169582 Streptococcus pneumoniae ATCC 700669 7327723 YP_002511140.1 CDS SPN23F_12010 NC_011900.1 1171762 1171920 R hypothetical protein complement(1171762..1171920) Streptococcus pneumoniae ATCC 700669 7327725 YP_002511141.1 CDS SPN23F_12060 NC_011900.1 1173713 1173898 R IS66 transposase Orf1 complement(1173713..1173898) Streptococcus pneumoniae ATCC 700669 7327730 YP_002511142.1 CDS ntpD NC_011900.1 1174171 1174782 R produces ATP from ADP in the presence of a proton gradient across the membrane; the D subunit is part of the catalytic core of the ATP synthase complex; V-type ATP synthase subunit D complement(1174171..1174782) Streptococcus pneumoniae ATCC 700669 7327731 YP_002511143.1 CDS ntpB NC_011900.1 1174805 1176190 R produces ATP from ADP in the presence of a proton gradient across the membrane; the B subunit is part of the catalytic core of the ATP synthase complex; V-type ATP synthase subunit B complement(1174805..1176190) Streptococcus pneumoniae ATCC 700669 7328429 YP_002511144.1 CDS ntpA NC_011900.1 1176191 1177966 R produces ATP from ADP in the presence of a proton gradient across the membrane; the A subunit is part of the catalytic core of the ATP synthase complex; V-type ATP synthase subunit A complement(1176191..1177966) Streptococcus pneumoniae ATCC 700669 7328427 YP_002511145.1 CDS SPN23F_12100 NC_011900.1 1178029 1178349 R produces ATP from ADP in the presence of a proton gradient across the membrane; the F subunit is part of the catalytic core of the ATP synthase complex; V-type ATP synthase subunit F complement(1178029..1178349) Streptococcus pneumoniae ATCC 700669 7328426 YP_002511146.1 CDS ntpC NC_011900.1 1178339 1179346 R V-type sodium ATP synthase subunit C complement(1178339..1179346) Streptococcus pneumoniae ATCC 700669 7327732 YP_002511147.1 CDS ntpE NC_011900.1 1179411 1179992 R V-type sodium ATP synthase subunit E complement(1179411..1179992) Streptococcus pneumoniae ATCC 700669 7328428 YP_002511148.1 CDS ntpK NC_011900.1 1180026 1180502 R produces ATP from ADP in the presence of a proton gradient across the membrane; the K subunit is a nonenzymatic component which binds the dimeric form by interacting with the G and E subunits; V-type ATP synthase subunit K complement(1180026..1180502) Streptococcus pneumoniae ATCC 700669 7328430 YP_002511149.1 CDS ntpI NC_011900.1 1180518 1182509 R Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit I is part of the membrane proton channel.; V-type ATP synthase subunit I complement(1180518..1182509) Streptococcus pneumoniae ATCC 700669 7328432 YP_002511150.1 CDS SPN23F_12150 NC_011900.1 1182499 1182822 R hypothetical protein complement(1182499..1182822) Streptococcus pneumoniae ATCC 700669 7328431 YP_002511151.1 CDS SPN23F_12160 NC_011900.1 1182847 1183737 R ROK family protein complement(1182847..1183737) Streptococcus pneumoniae ATCC 700669 7327733 YP_002511152.1 CDS SPN23F_12170 NC_011900.1 1183894 1185003 R oxidoreductase complement(1183894..1185003) Streptococcus pneumoniae ATCC 700669 7327734 YP_002511153.1 CDS SPN23F_12180 NC_011900.1 1185043 1187265 R sialidase (neuraminidase) complement(1185043..1187265) Streptococcus pneumoniae ATCC 700669 7327735 YP_002511154.1 CDS SPN23F_12190 NC_011900.1 1187267 1187725 R hypothetical protein complement(1187267..1187725) Streptococcus pneumoniae ATCC 700669 7327736 YP_002511155.1 CDS SPN23F_12200 NC_011900.1 1187751 1189292 R sodium:solute symporter complement(1187751..1189292) Streptococcus pneumoniae ATCC 700669 7327737 YP_002511156.1 CDS nanA NC_011900.1 1189320 1190237 R N-acetylneuraminate lyase complement(1189320..1190237) Streptococcus pneumoniae ATCC 700669 7327738 YP_002511157.1 CDS nanE NC_011900.1 1190262 1190951 R N-acetylmannosamine-6-phosphate 2-epimerase complement(1190262..1190951) Streptococcus pneumoniae ATCC 700669 7328414 YP_002511158.1 CDS SPN23F_12230 NC_011900.1 1191723 1192979 D IS1167 transposase 1191723..1192979 Streptococcus pneumoniae ATCC 700669 7328417 YP_002511159.1 CDS SPN23F_12240 NC_011900.1 1193090 1193701 R phosphosugar-binding transcriptional regulator complement(1193090..1193701) Streptococcus pneumoniae ATCC 700669 7327739 YP_002511160.1 CDS SPN23F_12250 NC_011900.1 1194026 1194634 D hypothetical protein 1194026..1194634 Streptococcus pneumoniae ATCC 700669 7328301 YP_002511161.1 CDS SPN23F_12260 NC_011900.1 1194869 1195708 R IS861 transposase Orf2 complement(1194869..1195708) Streptococcus pneumoniae ATCC 700669 7329594 YP_002511162.1 CDS SPN23F_12270 NC_011900.1 1195684 1196220 R IS861 transposase Orf1 complement(1195684..1196220) Streptococcus pneumoniae ATCC 700669 7329595 YP_002511163.1 CDS SPN23F_12280 NC_011900.1 1196516 1196653 R hypothetical protein complement(1196516..1196653) Streptococcus pneumoniae ATCC 700669 7329596 YP_002511164.1 CDS SPN23F_12290 NC_011900.1 1196787 1198106 R hypothetical protein complement(1196787..1198106) Streptococcus pneumoniae ATCC 700669 7329597 YP_002511165.1 CDS SPN23F_12300 NC_011900.1 1198109 1198849 R ABC transporter ATP-binding protein complement(1198109..1198849) Streptococcus pneumoniae ATCC 700669 7329598 YP_002511166.1 CDS SPN23F_12310 NC_011900.1 1198864 1200471 R ABC transporter ATP-binding protein complement(1198864..1200471) Streptococcus pneumoniae ATCC 700669 7329599 YP_002511167.1 CDS ptrB NC_011900.1 1200468 1202408 R protease II (oligopeptidase B) complement(1200468..1202408) Streptococcus pneumoniae ATCC 700669 7329600 YP_002511168.1 CDS SPN23F_12330 NC_011900.1 1202441 1205050 R lantibiotic synthetase complement(1202441..1205050) Streptococcus pneumoniae ATCC 700669 7327892 YP_002511169.1 CDS SPN23F_12340 NC_011900.1 1205229 1205366 R hypothetical protein complement(1205229..1205366) Streptococcus pneumoniae ATCC 700669 7329601 YP_002511170.1 CDS SPN23F_12350 NC_011900.1 1205568 1206155 R hypothetical protein complement(1205568..1206155) Streptococcus pneumoniae ATCC 700669 7329602 YP_002511171.1 CDS SPN23F_12370 NC_011900.1 1206404 1206784 R hypothetical protein complement(1206404..1206784) Streptococcus pneumoniae ATCC 700669 7329604 YP_002511172.1 CDS SPN23F_12380 NC_011900.1 1206777 1207100 R hypothetical protein complement(1206777..1207100) Streptococcus pneumoniae ATCC 700669 7329605 YP_002511173.1 CDS SPN23F_12390 NC_011900.1 1207108 1207362 R replication initiator protein complement(1207108..1207362) Streptococcus pneumoniae ATCC 700669 7329606 YP_002511174.1 CDS SPN23F_12400 NC_011900.1 1207362 1207532 R hypothetical protein complement(1207362..1207532) Streptococcus pneumoniae ATCC 700669 7329607 YP_002511175.1 CDS SPN23F_12410 NC_011900.1 1207785 1208972 R integrase complement(1207785..1208972) Streptococcus pneumoniae ATCC 700669 7329608 YP_002511176.1 CDS SPN23F_12420 NC_011900.1 1208944 1209213 R hypothetical protein complement(1208944..1209213) Streptococcus pneumoniae ATCC 700669 7329609 YP_002511177.1 CDS SPN23F_12430 NC_011900.1 1209814 1211643 R relaxase complement(1209814..1211643) Streptococcus pneumoniae ATCC 700669 7329610 YP_002511178.1 CDS SPN23F_12440 NC_011900.1 1211630 1211995 R mobilisation protein complement(1211630..1211995) Streptococcus pneumoniae ATCC 700669 7329611 YP_002511179.1 CDS SPN23F_12450 NC_011900.1 1212000 1212356 R mobilisation protein complement(1212000..1212356) Streptococcus pneumoniae ATCC 700669 7329612 YP_002511180.1 CDS SPN23F_12460 NC_011900.1 1212740 1212994 R hypothetical protein complement(1212740..1212994) Streptococcus pneumoniae ATCC 700669 7329613 YP_002511181.1 CDS SPN23F_12470 NC_011900.1 1213060 1217064 R DNA helicase II, UvrD complement(1213060..1217064) Streptococcus pneumoniae ATCC 700669 7329614 YP_002511182.1 CDS SPN23F_12480 NC_011900.1 1217186 1217572 R hypothetical protein complement(1217186..1217572) Streptococcus pneumoniae ATCC 700669 7329615 YP_002511183.1 CDS SPN23F_12490 NC_011900.1 1217644 1218594 R hypothetical protein complement(1217644..1218594) Streptococcus pneumoniae ATCC 700669 7329616 YP_002511184.1 CDS SPN23F_12500 NC_011900.1 1218679 1219797 R hypothetical protein complement(1218679..1219797) Streptococcus pneumoniae ATCC 700669 7329617 YP_002511185.1 CDS SPN23F_12510 NC_011900.1 1220059 1221855 R NTPase protein complement(1220059..1221855) Streptococcus pneumoniae ATCC 700669 7329618 YP_002511186.1 CDS SPN23F_12520 NC_011900.1 1222272 1222538 R hypothetical protein complement(1222272..1222538) Streptococcus pneumoniae ATCC 700669 7329619 YP_002511187.1 CDS SPN23F_12530 NC_011900.1 1222525 1223229 R phosphoserine phosphatase complement(1222525..1223229) Streptococcus pneumoniae ATCC 700669 7329620 YP_002511188.1 CDS SPN23F_12540 NC_011900.1 1223282 1223848 R hypothetical protein complement(1223282..1223848) Streptococcus pneumoniae ATCC 700669 7329621 YP_002511189.1 CDS SPN23F_12550 NC_011900.1 1223941 1224165 R hypothetical protein complement(1223941..1224165) Streptococcus pneumoniae ATCC 700669 7329622 YP_002511190.1 CDS SPN23F_12560 NC_011900.1 1224254 1224871 R hypothetical protein complement(1224254..1224871) Streptococcus pneumoniae ATCC 700669 7329623 YP_002511191.1 CDS SPN23F_12570 NC_011900.1 1225193 1225915 R hypothetical protein complement(1225193..1225915) Streptococcus pneumoniae ATCC 700669 7329624 YP_002511192.1 CDS rep NC_011900.1 1226244 1227167 D replication protein 1226244..1227167 Streptococcus pneumoniae ATCC 700669 7329625 YP_002511193.1 CDS SPN23F_12590 NC_011900.1 1228032 1228682 R chloramphenicol acetyltransferase complement(1228032..1228682) Streptococcus pneumoniae ATCC 700669 7327450 YP_002511194.1 CDS SPN23F_12600 NC_011900.1 1228853 1229101 R hypothetical protein complement(1228853..1229101) Streptococcus pneumoniae ATCC 700669 7329626 YP_002511195.1 CDS SPN23F_12610 NC_011900.1 1229340 1230128 R hypothetical protein complement(1229340..1230128) Streptococcus pneumoniae ATCC 700669 7329627 YP_002511196.1 CDS SPN23F_12620 NC_011900.1 1230604 1231362 R zeta toxin complement(1230604..1231362) Streptococcus pneumoniae ATCC 700669 7329628 YP_002511197.1 CDS SPN23F_12630 NC_011900.1 1231362 1231838 R epsilon antitoxin complement(1231362..1231838) Streptococcus pneumoniae ATCC 700669 7329629 YP_002511198.1 CDS SPN23F_12640 NC_011900.1 1231908 1232180 R hypothetical protein complement(1231908..1232180) Streptococcus pneumoniae ATCC 700669 7329630 YP_002511199.1 CDS SPN23F_12650 NC_011900.1 1232218 1232601 R hypothetical protein complement(1232218..1232601) Streptococcus pneumoniae ATCC 700669 7329631 YP_002511200.1 CDS SPN23F_12660 NC_011900.1 1232598 1232831 R hypothetical protein complement(1232598..1232831) Streptococcus pneumoniae ATCC 700669 7329632 YP_002511201.1 CDS SPN23F_12670 NC_011900.1 1232882 1233967 R hypothetical protein complement(1232882..1233967) Streptococcus pneumoniae ATCC 700669 7329633 YP_002511202.1 CDS SPN23F_12680 NC_011900.1 1233977 1234618 R hypothetical protein complement(1233977..1234618) Streptococcus pneumoniae ATCC 700669 7329634 YP_002511203.1 CDS SPN23F_12690 NC_011900.1 1234839 1236962 R lantibiotic transport/processing ATP-binding protein complement(1234839..1236962) Streptococcus pneumoniae ATCC 700669 7329635 YP_002511204.1 CDS SPN23F_12700 NC_011900.1 1236969 1240220 R lantibiotic synthetase complement(1236969..1240220) Streptococcus pneumoniae ATCC 700669 7329636 YP_002511205.1 CDS SPN23F_12701 NC_011900.1 1240303 1240518 R lantibiotic precursor complement(1240303..1240518) Streptococcus pneumoniae ATCC 700669 7329637 YP_002511206.1 CDS SPN23F_12710 NC_011900.1 1240663 1241343 R lantibiotic ABC transporter complement(1240663..1241343) Streptococcus pneumoniae ATCC 700669 7329638 YP_002511207.1 CDS SPN23F_12720 NC_011900.1 1241392 1242132 R lantibiotic ABC transporter complement(1241392..1242132) Streptococcus pneumoniae ATCC 700669 7329639 YP_002511208.1 CDS SPN23F_12730 NC_011900.1 1242125 1243060 R lantibiotic ABC transporter ATP-binding protein complement(1242125..1243060) Streptococcus pneumoniae ATCC 700669 7329640 YP_002511209.1 CDS SPN23F_12740 NC_011900.1 1243238 1243411 R hypothetical protein complement(1243238..1243411) Streptococcus pneumoniae ATCC 700669 7329641 YP_002511210.1 CDS SPN23F_12750 NC_011900.1 1243602 1244462 D transcriptional regulator 1243602..1244462 Streptococcus pneumoniae ATCC 700669 7329642 YP_002511211.1 CDS SPN23F_12760 NC_011900.1 1244545 1244835 R hypothetical protein complement(1244545..1244835) Streptococcus pneumoniae ATCC 700669 7329643 YP_002511212.1 CDS SPN23F_12770 NC_011900.1 1244849 1245133 R hypothetical protein complement(1244849..1245133) Streptococcus pneumoniae ATCC 700669 7329644 YP_002511214.1 CDS SPN23F_12790 NC_011900.1 1246260 1248071 R group II intron reverse transcriptase/maturase complement(1246260..1248071) Streptococcus pneumoniae ATCC 700669 7329645 YP_002511215.1 CDS SPN23F_12830 NC_011900.1 1254542 1255108 R hypothetical protein complement(1254542..1255108) Streptococcus pneumoniae ATCC 700669 7329648 YP_002511216.1 CDS SPN23F_12840 NC_011900.1 1255346 1258159 R Possible involvement with cell wall metabolism; conjugal transfer protein complement(1255346..1258159) Streptococcus pneumoniae ATCC 700669 7329649 YP_002511217.1 CDS SPN23F_12850 NC_011900.1 1258171 1260486 R conjugal transfer protein complement(1258171..1260486) Streptococcus pneumoniae ATCC 700669 7329650 YP_002511218.1 CDS SPN23F_12860 NC_011900.1 1260476 1260838 R hypothetical protein complement(1260476..1260838) Streptococcus pneumoniae ATCC 700669 7329651 YP_002511219.1 CDS SPN23F_12870 NC_011900.1 1260892 1261746 R hypothetical protein complement(1260892..1261746) Streptococcus pneumoniae ATCC 700669 7329652 YP_002511220.1 CDS SPN23F_12880 NC_011900.1 1261763 1262005 R hypothetical protein complement(1261763..1262005) Streptococcus pneumoniae ATCC 700669 7329653 YP_002511221.1 CDS traG NC_011900.1 1262026 1263906 R conjugal transfer protein TraG complement(1262026..1263906) Streptococcus pneumoniae ATCC 700669 7329654 YP_002511222.1 CDS SPN23F_12900 NC_011900.1 1263903 1264391 R hypothetical protein complement(1263903..1264391) Streptococcus pneumoniae ATCC 700669 7327581 YP_002511223.1 CDS SPN23F_12910 NC_011900.1 1264381 1264680 R hypothetical protein complement(1264381..1264680) Streptococcus pneumoniae ATCC 700669 7329655 YP_002511224.1 CDS SPN23F_12920 NC_011900.1 1264963 1265799 R hypothetical protein complement(1264963..1265799) Streptococcus pneumoniae ATCC 700669 7329656 YP_002511225.1 CDS SPN23F_12930 NC_011900.1 1265799 1266389 R hypothetical protein complement(1265799..1266389) Streptococcus pneumoniae ATCC 700669 7329657 YP_002511226.1 CDS orf23 NC_011900.1 1266820 1267134 D conjugative transposon protein 1266820..1267134 Streptococcus pneumoniae ATCC 700669 7329658 YP_002511227.1 CDS orf22 NC_011900.1 1267153 1267536 D conjugative transposon protein 1267153..1267536 Streptococcus pneumoniae ATCC 700669 7328447 YP_002511228.1 CDS orf21 NC_011900.1 1267565 1268950 D conjugative transposon FtsK/SpoIIIE-family protein 1267565..1268950 Streptococcus pneumoniae ATCC 700669 7328446 YP_002511229.1 CDS orf20 NC_011900.1 1269128 1270333 D conjugative transposon replication initiation factor 1269128..1270333 Streptococcus pneumoniae ATCC 700669 7328445 YP_002511230.1 CDS orf19 NC_011900.1 1270376 1270597 D conjugative transposon protein 1270376..1270597 Streptococcus pneumoniae ATCC 700669 7328444 YP_002511231.1 CDS orf18 NC_011900.1 1270714 1271211 D conjugative transposon protein 1270714..1271211 Streptococcus pneumoniae ATCC 700669 7328443 YP_002511232.1 CDS orf17 NC_011900.1 1271462 1271692 D conjugative transposon membrane protein 1271462..1271692 Streptococcus pneumoniae ATCC 700669 7328442 YP_002511233.1 CDS orf16 NC_011900.1 1271676 1274123 D conjugative transposon ATP/GTP-binding protein 1271676..1274123 Streptococcus pneumoniae ATCC 700669 7328441 YP_002511234.1 CDS orf15 NC_011900.1 1274126 1276276 D conjugative transposon membrane protein 1274126..1276276 Streptococcus pneumoniae ATCC 700669 7328440 YP_002511235.1 CDS orf14 NC_011900.1 1276295 1277296 D cell wall hydrolase 1276295..1277296 Streptococcus pneumoniae ATCC 700669 7328439 YP_002511236.1 CDS orf13 NC_011900.1 1277311 1278225 D conjugative transposon exported protein 1277311..1278225 Streptococcus pneumoniae ATCC 700669 7328438 YP_002511237.1 CDS tetM NC_011900.1 1278602 1280521 D conjugative transposon tetracycline resistance protein 1278602..1280521 Streptococcus pneumoniae ATCC 700669 7328437 YP_002511238.1 CDS orf9 NC_011900.1 1280867 1281220 R conjugative transposon regulatory protein complement(1280867..1281220) Streptococcus pneumoniae ATCC 700669 7329164 YP_002511239.1 CDS SPN23F_13061 NC_011900.1 1281350 1281496 D hypothetical protein 1281350..1281496 Streptococcus pneumoniae ATCC 700669 7328449 YP_002511240.1 CDS orf7 NC_011900.1 1281725 1282147 D conjugative transposon regulatory protein 1281725..1282147 Streptococcus pneumoniae ATCC 700669 7329659 YP_002511241.1 CDS xis NC_011900.1 1282835 1283038 D excisionase 1282835..1283038 Streptococcus pneumoniae ATCC 700669 7328448 YP_002511242.1 CDS SPN23F_13110 NC_011900.1 1284551 1285138 R CAAX amino terminal protease complement(1284551..1285138) Streptococcus pneumoniae ATCC 700669 7329661 YP_002511243.1 CDS SPN23F_13120 NC_011900.1 1285141 1285374 R hypothetical protein complement(1285141..1285374) Streptococcus pneumoniae ATCC 700669 7329662 YP_002511244.1 CDS SPN23F_13130 NC_011900.1 1285387 1285767 R hypothetical protein complement(1285387..1285767) Streptococcus pneumoniae ATCC 700669 7329663 YP_002511245.1 CDS SPN23F_13140 NC_011900.1 1285760 1286209 R hypothetical protein complement(1285760..1286209) Streptococcus pneumoniae ATCC 700669 7329664 YP_002511246.1 CDS SPN23F_13150 NC_011900.1 1286193 1287551 R DNA methylase complement(1286193..1287551) Streptococcus pneumoniae ATCC 700669 7329665 YP_002511247.1 CDS SPN23F_13160 NC_011900.1 1287650 1288429 R replication initiator protein complement(1287650..1288429) Streptococcus pneumoniae ATCC 700669 7329666 YP_002511248.1 CDS SPN23F_13170 NC_011900.1 1288426 1288599 R hypothetical protein complement(1288426..1288599) Streptococcus pneumoniae ATCC 700669 7329667 YP_002511249.1 CDS rplL NC_011900.1 1288801 1289169 R present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulates GTPase activity of translation factors; 50S ribosomal protein L7/L12 complement(1288801..1289169) Streptococcus pneumoniae ATCC 700669 7329668 YP_002511250.1 CDS rplJ NC_011900.1 1289245 1289745 R binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit; 50S ribosomal protein L10 complement(1289245..1289745) Streptococcus pneumoniae ATCC 700669 7327479 YP_002511251.1 CDS SPN23F_13210 NC_011900.1 1289995 1291254 R chlorohydrolase complement(1289995..1291254) Streptococcus pneumoniae ATCC 700669 7327477 YP_002511252.1 CDS SPN23F_13220 NC_011900.1 1291601 1293349 R ABC transporter ATP-binding protein complement(1291601..1293349) Streptococcus pneumoniae ATCC 700669 7329669 YP_002511253.1 CDS SPN23F_13230 NC_011900.1 1293351 1295075 R ABC transporter ATP-binding protein complement(1293351..1295075) Streptococcus pneumoniae ATCC 700669 7329670 YP_002511254.1 CDS msrAB NC_011900.1 1295133 1296071 R peptide methionine sulfoxide reductase complement(1295133..1296071) Streptococcus pneumoniae ATCC 700669 7329671 YP_002511255.1 CDS thrB NC_011900.1 1296321 1297190 R catalyzes the formation of O-phospho-L-homoserine from L-homoserine in threonine biosynthesis from asparate; homoserine kinase complement(1296321..1297190) Streptococcus pneumoniae ATCC 700669 7327819 YP_002511256.1 CDS hom NC_011900.1 1297192 1298478 R catalyzes the formation of L-aspartate 4-semialdehyde from L-homoserine; homoserine dehydrogenase complement(1297192..1298478) Streptococcus pneumoniae ATCC 700669 7329173 YP_002511257.1 CDS mecA NC_011900.1 1298629 1299366 R enables recognition and targeting of proteins for proteolysis, involved in negative regulation of competence; adaptor protein complement(1298629..1299366) Streptococcus pneumoniae ATCC 700669 7328074 YP_002511258.1 CDS SPN23F_13290 NC_011900.1 1299566 1300600 R hypothetical protein complement(1299566..1300600) Streptococcus pneumoniae ATCC 700669 7328124 YP_002511259.1 CDS SPN23F_13300 NC_011900.1 1300629 1302062 R Hydrophobicity plot and neighbouring genes suggest this may be a polysaccharide polymerase.; hypothetical protein complement(1300629..1302062) Streptococcus pneumoniae ATCC 700669 7329672 YP_002511260.1 CDS SPN23F_13310 NC_011900.1 1302078 1303064 R glycosyl transferase complement(1302078..1303064) Streptococcus pneumoniae ATCC 700669 7328541 YP_002511261.1 CDS SPN23F_13320 NC_011900.1 1303066 1304166 R glycosyl transferase complement(1303066..1304166) Streptococcus pneumoniae ATCC 700669 7329260 YP_002511262.1 CDS SPN23F_13330 NC_011900.1 1304159 1305004 R LicD-family phosphotransferase complement(1304159..1305004) Streptococcus pneumoniae ATCC 700669 7329261 YP_002511263.1 CDS SPN23F_13340 NC_011900.1 1305283 1306557 R Local genes and Pfam suggest that this may be related to cpsA; cell envelope-related transcriptional attenuator domain protein complement(1305283..1306557) Streptococcus pneumoniae ATCC 700669 7329262 YP_002511264.1 CDS pheA NC_011900.1 1306554 1307402 R catalyzes the formation of phenylpyruvate from prephenate in phenylalanine biosynthesis; prephenate dehydratase complement(1306554..1307402) Streptococcus pneumoniae ATCC 700669 7329263 YP_002511265.1 CDS aroK NC_011900.1 1307399 1307875 R shikimate kinase complement(1307399..1307875) Streptococcus pneumoniae ATCC 700669 7327841 YP_002511266.1 CDS aroA NC_011900.1 1307868 1309151 R catalyzes the formation of 5-O-(1-carboxyvinyl)-3-phosphoshikimate from phosphoenolpyruvate and 3-phosphoshikimate in tryptophan biosynthesis; 3-phosphoshikimate 1-carboxyvinyltransferase complement(1307868..1309151) Streptococcus pneumoniae ATCC 700669 7328665 YP_002511267.1 CDS SPN23F_13380 NC_011900.1 1309243 1309581 R hypothetical protein complement(1309243..1309581) Streptococcus pneumoniae ATCC 700669 7328658 YP_002511268.1 CDS tyrA NC_011900.1 1309592 1310695 R catalyzes the formation of 4-hydroxyphenylpyruvate from prephenate; prephenate dehydrogenase complement(1309592..1310695) Streptococcus pneumoniae ATCC 700669 7329264 YP_002511269.1 CDS aroF NC_011900.1 1310705 1311871 R catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis; chorismate synthase complement(1310705..1311871) Streptococcus pneumoniae ATCC 700669 7327657 YP_002511270.1 CDS aroB NC_011900.1 1311881 1312948 R catalyzes the formation of 3-dehydroquinate from 3-deoxy-arabino-heptulonate 7-phosphate; functions in aromatic amino acid biosynthesis; 3-dehydroquinate synthase complement(1311881..1312948) Streptococcus pneumoniae ATCC 700669 7328662 YP_002511271.1 CDS aroE NC_011900.1 1312967 1313821 R AroE; catalyzes the conversion of shikimate to 3-dehydroshikimate; shikimate 5-dehydrogenase complement(1312967..1313821) Streptococcus pneumoniae ATCC 700669 7328659 YP_002511272.1 CDS aroD NC_011900.1 1313811 1314488 R catalyzes the dehydration of 3-dehydroquinate to form 3-dehydroshikimate in aromatic amino acid biosynthesis; 3-dehydroquinate dehydratase complement(1313811..1314488) Streptococcus pneumoniae ATCC 700669 7328661 YP_002511273.1 CDS SPN23F_13440 NC_011900.1 1314485 1315657 R hypothetical protein complement(1314485..1315657) Streptococcus pneumoniae ATCC 700669 7328660 YP_002511274.1 CDS SPN23F_13450 NC_011900.1 1316333 1317967 R hypothetical protein complement(1316333..1317967) Streptococcus pneumoniae ATCC 700669 7329265 YP_002511275.1 CDS SPN23F_13460 NC_011900.1 1317948 1318697 R ABC transporter ATP-binding protein complement(1317948..1318697) Streptococcus pneumoniae ATCC 700669 7329266 YP_002511276.1 CDS SPN23F_13470 NC_011900.1 1318876 1320330 D converts 1,4-alpha-D-glucans to maltodextrin; cytoplasmic alpha-amylase 1318876..1320330 Streptococcus pneumoniae ATCC 700669 7329267 YP_002511277.1 CDS alaS NC_011900.1 1320420 1323038 R Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; alanyl-tRNA synthetase complement(1320420..1323038) Streptococcus pneumoniae ATCC 700669 7329268 YP_002511278.1 CDS SPN23F_13490 NC_011900.1 1323060 1323545 R hypothetical protein complement(1323060..1323545) Streptococcus pneumoniae ATCC 700669 7328644 YP_002511279.1 CDS potD NC_011900.1 1324320 1325390 R spermidine/putrescine extracellular binding protein complement(1324320..1325390) Streptococcus pneumoniae ATCC 700669 7329269 YP_002511280.1 CDS potC NC_011900.1 1325387 1326160 R spermidine/putrescine ABC transporter permease complement(1325387..1326160) Streptococcus pneumoniae ATCC 700669 7327868 YP_002511281.1 CDS potB NC_011900.1 1326157 1326963 R spermidine/putrescine ABC transporter permease complement(1326157..1326963) Streptococcus pneumoniae ATCC 700669 7327867 YP_002511282.1 CDS potA NC_011900.1 1326944 1328101 R spermidine/putrescine ABC transporter ATP-binding protein complement(1326944..1328101) Streptococcus pneumoniae ATCC 700669 7327866 YP_002511283.1 CDS murB NC_011900.1 1328160 1329110 R catalyzes the reduction of UDP-N-acetylglucosamine enolpyruvate to form UDP-N-acetylmuramate in peptidoglycan biosynthesis; UDP-N-acetylenolpyruvoylglucosamine reductase complement(1328160..1329110) Streptococcus pneumoniae ATCC 700669 7327865 YP_002511284.1 CDS SPN23F_13550 NC_011900.1 1329222 1329974 R hypothetical protein complement(1329222..1329974) Streptococcus pneumoniae ATCC 700669 7328392 YP_002511285.1 CDS aldB NC_011900.1 1329984 1330715 R alpha-acetolactate decarboxylase complement(1329984..1330715) Streptococcus pneumoniae ATCC 700669 7329270 YP_002511286.1 CDS SPN23F_13570 NC_011900.1 1330857 1332128 D GntR family transcriptional regulator 1330857..1332128 Streptococcus pneumoniae ATCC 700669 7328645 YP_002511287.1 CDS SPN23F_13580 NC_011900.1 1332148 1332963 R extracellular amino acid-binding protein complement(1332148..1332963) Streptococcus pneumoniae ATCC 700669 7329271 YP_002511288.1 CDS phoU NC_011900.1 1333120 1333773 R phosphate transport system protein complement(1333120..1333773) Streptococcus pneumoniae ATCC 700669 7329272 YP_002511289.1 CDS pstB1 NC_011900.1 1333785 1334543 R ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation; phosphate transporter ATP-binding protein complement(1333785..1334543) Streptococcus pneumoniae ATCC 700669 7327846 YP_002511290.1 CDS pstB2 NC_011900.1 1334556 1335359 R ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation; phosphate transporter ATP-binding protein complement(1334556..1335359) Streptococcus pneumoniae ATCC 700669 7327885 YP_002511291.1 CDS SPN23F_13620 NC_011900.1 1335370 1336254 R phosphate ABC transporter permease complement(1335370..1336254) Streptococcus pneumoniae ATCC 700669 7327886 YP_002511292.1 CDS SPN23F_13630 NC_011900.1 1336244 1336693 R phosphate ABC transporter permease complement(1336244..1336693) Streptococcus pneumoniae ATCC 700669 7329273 YP_002511293.1 CDS SPN23F_13640 NC_011900.1 1336745 1337161 R phosphate ABC transporter permease complement(1336745..1337161) Streptococcus pneumoniae ATCC 700669 7329274 YP_002511294.1 CDS pstS NC_011900.1 1337161 1338039 R phosphate ABC transporter substrate-binding protein complement(1337161..1338039) Streptococcus pneumoniae ATCC 700669 7329275 YP_002511295.1 CDS SPN23F_13670 NC_011900.1 1338613 1339917 R NOL1/NOP2/sun family protein complement(1338613..1339917) Streptococcus pneumoniae ATCC 700669 7327889 YP_002511296.1 CDS SPN23F_13680 NC_011900.1 1339918 1340691 R myo-inositol-1(or 4)-monophosphatase complement(1339918..1340691) Streptococcus pneumoniae ATCC 700669 7329276 YP_002511297.1 CDS SPN23F_13690 NC_011900.1 1340681 1340899 R hypothetical protein complement(1340681..1340899) Streptococcus pneumoniae ATCC 700669 7329277 YP_002511298.1 CDS spxA NC_011900.1 1340959 1341360 R the anti-alpha factor Spx interacts with RNA polymerase alpha subunit C-terminal domain in a region that interacts with the sigma 70 subunit and may interfere with activation of promoters; in Bacillus subtilis this protein is a substrate for ClpXP protease; blocks transcription of the competence regulatory gene encoded by the srf operon; regulates a number of genes involved in thiol homeostasis including trxA and trxB; monomeric member of ArsC family of proteins; does not bind DNA; contains a disulfide bond between C10 and C13 which may sense disulfide stress; Spx family transcriptional regulator complement(1340959..1341360) Streptococcus pneumoniae ATCC 700669 7329278 YP_002511299.1 CDS SPN23F_13710 NC_011900.1 1341570 1342187 R hypothetical protein complement(1341570..1342187) Streptococcus pneumoniae ATCC 700669 7329151 YP_002511300.1 CDS SPN23F_13720 NC_011900.1 1342177 1342950 R haloacid dehalogenase-like hydrolase complement(1342177..1342950) Streptococcus pneumoniae ATCC 700669 7329279 YP_002511301.1 CDS SPN23F_13730 NC_011900.1 1342961 1343698 R acyl-ACP thioesterase complement(1342961..1343698) Streptococcus pneumoniae ATCC 700669 7329280 YP_002511302.1 CDS hemN NC_011900.1 1343703 1344833 R catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III; coproporphyrinogen III oxidase complement(1343703..1344833) Streptococcus pneumoniae ATCC 700669 7329281 YP_002511303.1 CDS SPN23F_13750 NC_011900.1 1344917 1345306 R exported hydrophilic protein complement(1344917..1345306) Streptococcus pneumoniae ATCC 700669 7328069 YP_002511304.1 CDS SPN23F_13760 NC_011900.1 1345322 1345705 R hypothetical protein complement(1345322..1345705) Streptococcus pneumoniae ATCC 700669 7329282 YP_002511305.1 CDS lgt NC_011900.1 1345706 1346494 R transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein; prolipoprotein diacylglyceryl transferase complement(1345706..1346494) Streptococcus pneumoniae ATCC 700669 7329283 YP_002511306.1 CDS ptsK NC_011900.1 1346487 1347422 R catalyzes the phosphorylation of the phosphocarrier protein HPr of the bacterial phosphotransferase system; HPr kinase/phosphorylase complement(1346487..1347422) Streptococcus pneumoniae ATCC 700669 7328106 YP_002511307.1 CDS rpsU NC_011900.1 1347552 1347728 R a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA; 30S ribosomal protein S21 complement(1347552..1347728) Streptococcus pneumoniae ATCC 700669 7327894 YP_002511308.1 CDS nagB NC_011900.1 1347868 1348575 R glucosamine-6-phosphate isomerase complement(1347868..1348575) Streptococcus pneumoniae ATCC 700669 7329127 YP_002511309.1 CDS queA NC_011900.1 1348726 1349754 D Synthesizes oQ from preQ1 in a single S-adenosylmethionine-requiring step; S-adenosylmethionine:tRNA ribosyltransferase-isomerase 1348726..1349754 Streptococcus pneumoniae ATCC 700669 7328413 YP_002511310.1 CDS SPN23F_13830 NC_011900.1 1352264 1352815 R GNAT family acetyltransferase complement(1352264..1352815) Streptococcus pneumoniae ATCC 700669 7329284 YP_002511311.1 CDS nadE NC_011900.1 1353165 1353989 R catalyzes the formation of nicotinamide adenine dinucleotide (NAD) from nicotinic acid adenine dinucleotide (NAAD) using either ammonia or glutamine as the amide donor and ATP; ammonia-utilizing enzymes include the ones from Bacillus and Escherichia coli while glutamine-utilizing enzymes include the Mycobacterial one; forms homodimers; NAD synthetase complement(1353165..1353989) Streptococcus pneumoniae ATCC 700669 7329285 YP_002511312.1 CDS SPN23F_13850 NC_011900.1 1353986 1355446 R catalyzes the formation of 5-phospho-alpha-D-ribose 1-diphosphate and nicotinate from nicotinate D-ribonucleotide and diphosphate; nicotinate phosphoribosyltransferase complement(1353986..1355446) Streptococcus pneumoniae ATCC 700669 7328412 YP_002511313.1 CDS SPN23F_13860 NC_011900.1 1355562 1356050 R hypothetical protein complement(1355562..1356050) Streptococcus pneumoniae ATCC 700669 7329286 YP_002511314.1 CDS SPN23F_13870 NC_011900.1 1356040 1356249 R DNA-binding protein complement(1356040..1356249) Streptococcus pneumoniae ATCC 700669 7329287 YP_002511315.1 CDS SPN23F_13880 NC_011900.1 1356635 1357114 R hypothetical protein complement(1356635..1357114) Streptococcus pneumoniae ATCC 700669 7329288 YP_002511316.1 CDS SPN23F_13910 NC_011900.1 1358358 1359083 R peptidase complement(1358358..1359083) Streptococcus pneumoniae ATCC 700669 7329291 YP_002511317.1 CDS SPN23F_13930 NC_011900.1 1359672 1360958 R peptidase complement(1359672..1360958) Streptococcus pneumoniae ATCC 700669 7329292 YP_002511318.1 CDS SPN23F_13960 NC_011900.1 1362136 1363326 D DNA modification methylase 1362136..1363326 Streptococcus pneumoniae ATCC 700669 7329294 YP_002511319.1 CDS SPN23F_13980 NC_011900.1 1363841 1364833 R AraC family transcriptional regulator complement(1363841..1364833) Streptococcus pneumoniae ATCC 700669 7329295 YP_002511320.1 CDS SPN23F_13990 NC_011900.1 1364993 1366747 D ABC transporter 1364993..1366747 Streptococcus pneumoniae ATCC 700669 7329296 YP_002511321.1 CDS SPN23F_14000 NC_011900.1 1366731 1368452 D ABC transporter 1366731..1368452 Streptococcus pneumoniae ATCC 700669 7329297 YP_002511322.1 CDS SPN23F_14010 NC_011900.1 1368463 1369047 D hypothetical protein 1368463..1369047 Streptococcus pneumoniae ATCC 700669 7329298 YP_002511323.1 CDS SPN23F_14020 NC_011900.1 1369047 1369742 D hypothetical protein 1369047..1369742 Streptococcus pneumoniae ATCC 700669 7329299 YP_002511324.1 CDS SPN23F_14030 NC_011900.1 1369730 1371094 D ABC transporter 1369730..1371094 Streptococcus pneumoniae ATCC 700669 7329300 YP_002511325.1 CDS SPN23F_14080 NC_011900.1 1373293 1373643 R transposase complement(1373293..1373643) Streptococcus pneumoniae ATCC 700669 7329303 YP_002511326.1 CDS SPN23F_14090 NC_011900.1 1373624 1373809 R IS66 family element, orf1 complement(1373624..1373809) Streptococcus pneumoniae ATCC 700669 7329304 YP_002511327.1 CDS guaA NC_011900.1 1374113 1375675 R contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway; GMP synthase complement(1374113..1375675) Streptococcus pneumoniae ATCC 700669 7329305 YP_002511328.1 CDS SPN23F_14110 NC_011900.1 1375817 1376515 D GntR family transcriptional regulator 1375817..1376515 Streptococcus pneumoniae ATCC 700669 7328063 YP_002511329.1 CDS SPN23F_14120 NC_011900.1 1376558 1377454 R hypothetical protein complement(1376558..1377454) Streptococcus pneumoniae ATCC 700669 7329306 YP_002511330.1 CDS SPN23F_14130 NC_011900.1 1377463 1378398 R beta-lactamase complement(1377463..1378398) Streptococcus pneumoniae ATCC 700669 7329307 YP_002511331.1 CDS SPN23F_14140 NC_011900.1 1378395 1379120 R hypothetical protein complement(1378395..1379120) Streptococcus pneumoniae ATCC 700669 7329308 YP_002511332.1 CDS SPN23F_14150 NC_011900.1 1379204 1379839 R GDSL-like Lipase/acylhydrolase family protein complement(1379204..1379839) Streptococcus pneumoniae ATCC 700669 7329309 YP_002511333.1 CDS SPN23F_14160 NC_011900.1 1379841 1380668 R haloacid dehalogenase-like hydrolase complement(1379841..1380668) Streptococcus pneumoniae ATCC 700669 7329310 YP_002511334.1 CDS def NC_011900.1 1382255 1382866 D cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+); peptide deformylase 1382255..1382866 Streptococcus pneumoniae ATCC 700669 7329312 YP_002511335.1 CDS SPN23F_14210 NC_011900.1 1382911 1383639 D SpoU rRNA methylase family protein 1382911..1383639 Streptococcus pneumoniae ATCC 700669 7329224 YP_002511336.1 CDS SPN23F_14220 NC_011900.1 1383678 1384589 R thioredoxin reductase complement(1383678..1384589) Streptococcus pneumoniae ATCC 700669 7329313 YP_002511337.1 CDS SPN23F_14230 NC_011900.1 1384655 1384879 R hypothetical protein complement(1384655..1384879) Streptococcus pneumoniae ATCC 700669 7329314 YP_002511338.1 CDS SPN23F_14240 NC_011900.1 1384957 1385700 R ABC transporter ATP-binding protein complement(1384957..1385700) Streptococcus pneumoniae ATCC 700669 7329315 YP_002511339.1 CDS SPN23F_14250 NC_011900.1 1385700 1386500 R ABC transporter permease complement(1385700..1386500) Streptococcus pneumoniae ATCC 700669 7329316 YP_002511340.1 CDS SPN23F_14260 NC_011900.1 1386658 1387014 R ArsC family transcriptional regulator complement(1386658..1387014) Streptococcus pneumoniae ATCC 700669 7329317 YP_002511341.1 CDS ogt NC_011900.1 1387027 1387539 R methylated-DNA--protein-cysteine methyltransferase complement(1387027..1387539) Streptococcus pneumoniae ATCC 700669 7329318 YP_002511342.1 CDS SPN23F_14280 NC_011900.1 1387539 1388033 R GNAT family acetyltransferase complement(1387539..1388033) Streptococcus pneumoniae ATCC 700669 7328436 YP_002511343.1 CDS SPN23F_14290 NC_011900.1 1388168 1388614 D hypothetical protein 1388168..1388614 Streptococcus pneumoniae ATCC 700669 7329319 YP_002511344.1 CDS SPN23F_14300 NC_011900.1 1388611 1389258 D hemolysin-III-like membrane protein 1388611..1389258 Streptococcus pneumoniae ATCC 700669 7329320 YP_002511345.1 CDS SPN23F_14310 NC_011900.1 1389279 1389860 R with PdxST is involved in the biosynthesis of pyridoxal 5'-phosphate; PdxT catalyzes the hydrolysis of glutamine to glutamate and ammonia; PdxS utilizes the ammonia to synthesize pyridoxal 5'-phosphate; glutamine amidotransferase subunit PdxT complement(1389279..1389860) Streptococcus pneumoniae ATCC 700669 7329321 YP_002511346.1 CDS SPN23F_14320 NC_011900.1 1389861 1390736 R with PdxT forms pyridoxal 5'-phosphate from glutamine, either ribose 5-phosphate or ribulose 5-phosphate, and either glyceraldehyde 3-phosphate or dihydroxyacetone phosphate; pyridoxal biosynthesis lyase PdxS complement(1389861..1390736) Streptococcus pneumoniae ATCC 700669 7329322 YP_002511347.1 CDS nox NC_011900.1 1390888 1392267 R NADH oxidase complement(1390888..1392267) Streptococcus pneumoniae ATCC 700669 7329323 YP_002511348.1 CDS SPN23F_14350 NC_011900.1 1392561 1393484 D ApbE family protein 1392561..1393484 Streptococcus pneumoniae ATCC 700669 7328421 YP_002511349.1 CDS SPN23F_14360 NC_011900.1 1393544 1394149 D NADPH-dependent FMN reductase 1393544..1394149 Streptococcus pneumoniae ATCC 700669 7329324 YP_002511350.1 CDS SPN23F_14370 NC_011900.1 1394167 1395411 D NADPH-dependent FMN reductase 1394167..1395411 Streptococcus pneumoniae ATCC 700669 7329325 YP_002511351.1 CDS SPN23F_14380 NC_011900.1 1395634 1395891 R hypothetical protein complement(1395634..1395891) Streptococcus pneumoniae ATCC 700669 7329326 YP_002511352.1 CDS glyS NC_011900.1 1395933 1397969 R glycine--tRNA ligase beta chain; glyS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; glycyl-tRNA synthetase subunit beta complement(1395933..1397969) Streptococcus pneumoniae ATCC 700669 7329327 YP_002511353.1 CDS glyQ NC_011900.1 1398229 1399146 R glycine--tRNA ligase alpha chain; GlyRS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; glycyl-tRNA synthetase subunit alpha complement(1398229..1399146) Streptococcus pneumoniae ATCC 700669 7328615 YP_002511354.1 CDS SPN23F_14410 NC_011900.1 1399165 1399926 R hypothetical protein complement(1399165..1399926) Streptococcus pneumoniae ATCC 700669 7328614 YP_002511355.1 CDS SPN23F_14420 NC_011900.1 1400199 1401041 R aldo/keto reductase family protein complement(1400199..1401041) Streptococcus pneumoniae ATCC 700669 7329328 YP_002511356.1 CDS SPN23F_14430 NC_011900.1 1401155 1402492 R polysaccharide deacetylase complement(1401155..1402492) Streptococcus pneumoniae ATCC 700669 7329329 YP_002511357.1 CDS SPN23F_14440 NC_011900.1 1402781 1403158 R hypothetical protein complement(1402781..1403158) Streptococcus pneumoniae ATCC 700669 7329330 YP_002511358.1 CDS SPN23F_14450 NC_011900.1 1403373 1404350 D oxidoreductase 1403373..1404350 Streptococcus pneumoniae ATCC 700669 7329331 YP_002511359.1 CDS SPN23F_14460 NC_011900.1 1404347 1405429 D RNA helicase 1404347..1405429 Streptococcus pneumoniae ATCC 700669 7329332 YP_002511360.1 CDS tufA NC_011900.1 1408400 1409596 R EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu; elongation factor Tu complement(1408400..1409596) Streptococcus pneumoniae ATCC 700669 7329336 YP_002511361.1 CDS SPN23F_14540 NC_011900.1 1409760 1410713 R IS1239 transposase complement(1409760..1410713) Streptococcus pneumoniae ATCC 700669 7327656 YP_002511362.1 CDS gla NC_011900.1 1411751 1412620 R glycerol facilitator-aquaporin complement(1411751..1412620) Streptococcus pneumoniae ATCC 700669 7329337 YP_002511363.1 CDS SPN23F_14590 NC_011900.1 1414540 1414791 R hypothetical protein complement(1414540..1414791) Streptococcus pneumoniae ATCC 700669 7329338 YP_002511364.1 CDS pgmA NC_011900.1 1416213 1417931 D phosphomannomutase 1416213..1417931 Streptococcus pneumoniae ATCC 700669 7328703 YP_002511365.1 CDS SPN23F_14640 NC_011900.1 1418042 1418389 D hypothetical protein 1418042..1418389 Streptococcus pneumoniae ATCC 700669 7327839 YP_002511366.1 CDS SPN23F_14650 NC_011900.1 1418667 1419503 R amino acid ABC transporter substrate-binding protein complement(1418667..1419503) Streptococcus pneumoniae ATCC 700669 7328704 YP_002511367.1 CDS SPN23F_14660 NC_011900.1 1419516 1420145 R amino acid ABC transporter ATP-binding protein complement(1419516..1420145) Streptococcus pneumoniae ATCC 700669 7328705 YP_002511368.1 CDS SPN23F_14670 NC_011900.1 1420155 1420796 R amino acid ABC transporter permease complement(1420155..1420796) Streptococcus pneumoniae ATCC 700669 7328706 YP_002511369.1 CDS SPN23F_14680 NC_011900.1 1420942 1422171 R hypothetical protein complement(1420942..1422171) Streptococcus pneumoniae ATCC 700669 7328707 YP_002511370.1 CDS SPN23F_14690 NC_011900.1 1422161 1423327 R hypothetical protein complement(1422161..1423327) Streptococcus pneumoniae ATCC 700669 7328708 YP_002511371.1 CDS SPN23F_14700 NC_011900.1 1423471 1424484 D hypothetical protein 1423471..1424484 Streptococcus pneumoniae ATCC 700669 7328709 YP_002511372.1 CDS atpC NC_011900.1 1424529 1424948 R part of catalytic core of ATP synthase; alpha(3)beta(3)gamma(1)delta(1)epsilon(1); involved in producing ATP from ADP in the presence of the proton motive force across the membrane; F0F1 ATP synthase subunit epsilon complement(1424529..1424948) Streptococcus pneumoniae ATCC 700669 7328710 YP_002511373.1 CDS atpD NC_011900.1 1424959 1426365 R Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit; F0F1 ATP synthase subunit beta complement(1424959..1426365) Streptococcus pneumoniae ATCC 700669 7328674 YP_002511374.1 CDS atpG NC_011900.1 1426451 1427329 R Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is a regulatory subunit; F0F1 ATP synthase subunit gamma complement(1426451..1427329) Streptococcus pneumoniae ATCC 700669 7328675 YP_002511375.1 CDS atpA NC_011900.1 1427345 1428850 R produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit; F0F1 ATP synthase subunit alpha complement(1427345..1428850) Streptococcus pneumoniae ATCC 700669 7328678 YP_002511376.1 CDS atpH NC_011900.1 1428865 1429401 R Produces ATP from ADP in the presence of a proton gradient across the membrane; the delta subunit is part of the catalytic core of the ATP synthase complex; F0F1 ATP synthase subunit delta complement(1428865..1429401) Streptococcus pneumoniae ATCC 700669 7328672 YP_002511377.1 CDS atpF NC_011900.1 1429401 1429895 R Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit B is part of the membrane proton channel.; F0F1 ATP synthase subunit B complement(1429401..1429895) Streptococcus pneumoniae ATCC 700669 7328679 YP_002511378.1 CDS atpB NC_011900.1 1429909 1430625 R Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0; F0F1 ATP synthase subunit A complement(1429909..1430625) Streptococcus pneumoniae ATCC 700669 7328677 YP_002511379.1 CDS atpE NC_011900.1 1430660 1430860 R produces ATP from ADP in the presence of a proton gradient across the membrane; subunit C is part of the membrane proton channel F0; F0F1 ATP synthase subunit C complement(1430660..1430860) Streptococcus pneumoniae ATCC 700669 7328673 YP_002511380.1 CDS SPN23F_14790 NC_011900.1 1430935 1431942 R insertion sequence IS1239 transposase complement(1430935..1431942) Streptococcus pneumoniae ATCC 700669 7328676 YP_002511381.1 CDS SPN23F_14800 NC_011900.1 1432387 1432815 R acetyltransferase complement(1432387..1432815) Streptococcus pneumoniae ATCC 700669 7328711 YP_002511382.1 CDS greA NC_011900.1 1433113 1433595 R necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus; transcription elongation factor GreA complement(1433113..1433595) Streptococcus pneumoniae ATCC 700669 7328712 YP_002511383.1 CDS SPN23F_14820 NC_011900.1 1433666 1435321 R aminodeoxychorismate lyase complement(1433666..1435321) Streptococcus pneumoniae ATCC 700669 7328621 YP_002511384.1 CDS SPN23F_14830 NC_011900.1 1435402 1435896 R GNAT family acetyltransferase complement(1435402..1435896) Streptococcus pneumoniae ATCC 700669 7328713 YP_002511385.1 CDS SPN23F_14840 NC_011900.1 1435893 1436357 R GNAT family acetyltransferase. GNAT family acetyltransferase complement(1435893..1436357) Streptococcus pneumoniae ATCC 700669 7328714 YP_002511386.1 CDS murC NC_011900.1 1436367 1437701 R Catalyzes the formation of UDP-N-acetylmuramoyl-L-alanine from UDP-N-acetylmuramate and L-alanine in peptidoglycan synthesis; UDP-N-acetylmuramate--L-alanine ligase complement(1436367..1437701) Streptococcus pneumoniae ATCC 700669 7328715 YP_002511387.1 CDS SPN23F_14860 NC_011900.1 1437712 1438350 R ATP-binding protein complement(1437712..1438350) Streptococcus pneumoniae ATCC 700669 7328393 YP_002511388.1 CDS SPN23F_14870 NC_011900.1 1438398 1441496 R SNF-family helicase complement(1438398..1441496) Streptococcus pneumoniae ATCC 700669 7328716 YP_002511389.1 CDS SPN23F_14880 NC_011900.1 1441589 1442755 R aminotransferase complement(1441589..1442755) Streptococcus pneumoniae ATCC 700669 7328717 YP_002511390.1 CDS SPN23F_14890 NC_011900.1 1442763 1443857 R catalyzes the formation of cystathionine from L-cysteine and O-succinyl-L-homoserine; cystathionine gamma-synthase complement(1442763..1443857) Streptococcus pneumoniae ATCC 700669 7328718 YP_002511391.1 CDS SPN23F_14900 NC_011900.1 1444015 1445697 R ABC transporter ATP-binding protein complement(1444015..1445697) Streptococcus pneumoniae ATCC 700669 7328719 YP_002511392.1 CDS SPN23F_14910 NC_011900.1 1445869 1447827 R extracellular oligopeptide-binding protein complement(1445869..1447827) Streptococcus pneumoniae ATCC 700669 7328720 YP_002511393.1 CDS SPN23F_14920 NC_011900.1 1448031 1449653 R polysaccharide biosynthesis protein complement(1448031..1449653) Streptococcus pneumoniae ATCC 700669 7328721 YP_002511394.1 CDS murE NC_011900.1 1449759 1451204 D involved in cell wall formation; peptidoglycan synthesis; cytoplasmic enzyme; catalyzes the addition of lysine to UDP-N-acetylmuramoyl-L-alanyl-D-glutamate forming UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysine; UDP-N-acetylmuramoylalanyl-D-glutamate--L-lysine ligase 1449759..1451204 Streptococcus pneumoniae ATCC 700669 7328722 YP_002511395.1 CDS SPN23F_14940 NC_011900.1 1451247 1451444 R CsbD-like protein complement(1451247..1451444) Streptococcus pneumoniae ATCC 700669 7328395 YP_002511396.1 CDS SPN23F_14950 NC_011900.1 1451545 1452141 R hypothetical protein complement(1451545..1452141) Streptococcus pneumoniae ATCC 700669 7328723 YP_002511397.1 CDS SPN23F_14960 NC_011900.1 1452178 1452690 R hypothetical protein complement(1452178..1452690) Streptococcus pneumoniae ATCC 700669 7328724 YP_002511398.1 CDS ppaC NC_011900.1 1452776 1453711 R catalyzes the hydrolysis of pyrophosphate to phosphate; manganese-dependent inorganic pyrophosphatase complement(1452776..1453711) Streptococcus pneumoniae ATCC 700669 7328725 YP_002511399.1 CDS SPN23F_14980 NC_011900.1 1453782 1454081 R hypothetical protein complement(1453782..1454081) Streptococcus pneumoniae ATCC 700669 7327869 YP_002511400.1 CDS SPN23F_14990 NC_011900.1 1454071 1454820 R hypothetical protein complement(1454071..1454820) Streptococcus pneumoniae ATCC 700669 7328726 YP_002511401.1 CDS SPN23F_15000 NC_011900.1 1454874 1455233 R hypothetical protein complement(1454874..1455233) Streptococcus pneumoniae ATCC 700669 7328727 YP_002511402.1 CDS SPN23F_15010 NC_011900.1 1455235 1456635 R cyclophilin type peptidyl-prolyl cis-trans isomerase protein complement(1455235..1456635) Streptococcus pneumoniae ATCC 700669 7328728 YP_002511403.1 CDS rpsR NC_011900.1 1456930 1457169 R binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit; 30S ribosomal protein S18 complement(1456930..1457169) Streptococcus pneumoniae ATCC 700669 7328729 YP_002511404.1 CDS ssb NC_011900.1 1457201 1457671 R binds to single stranded DNA and may facilitate the binding and interaction of other proteins to DNA; single-stranded DNA-binding protein complement(1457201..1457671) Streptococcus pneumoniae ATCC 700669 7329124 YP_002511405.1 CDS rpsF NC_011900.1 1457683 1457973 R binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21; 30S ribosomal protein S6 complement(1457683..1457973) Streptococcus pneumoniae ATCC 700669 7329154 YP_002511406.1 CDS asnC NC_011900.1 1458126 1459469 R catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; asparaginyl-tRNA synthetase complement(1458126..1459469) Streptococcus pneumoniae ATCC 700669 7329113 YP_002511407.1 CDS SPN23F_15060 NC_011900.1 1459488 1459853 R hypothetical protein complement(1459488..1459853) Streptococcus pneumoniae ATCC 700669 7328669 YP_002511408.1 CDS aspC NC_011900.1 1459846 1461033 R catalyzes the formation of oxalozcetate and L-glutamate from L-aspartate and 2-oxoglutarate; aspartate aminotransferase complement(1459846..1461033) Streptococcus pneumoniae ATCC 700669 7328730 YP_002511409.1 CDS SPN23F_15080 NC_011900.1 1461030 1461518 R hypothetical protein complement(1461030..1461518) Streptococcus pneumoniae ATCC 700669 7328670 YP_002511410.1 CDS pclA NC_011900.1 1461839 1462387 D NADPH-dependent FMN reductase 1461839..1462387 Streptococcus pneumoniae ATCC 700669 7328731 YP_002511411.1 CDS SPN23F_15110 NC_011900.1 1462624 1467948 R collagen-like surface-anchored protein complement(1462624..1467948) Streptococcus pneumoniae ATCC 700669 7328458 YP_002511412.1 CDS SPN23F_15120 NC_011900.1 1468164 1469648 D Mga-like regulatory protein 1468164..1469648 Streptococcus pneumoniae ATCC 700669 7328732 YP_002511413.1 CDS SPN23F_15130 NC_011900.1 1469699 1470427 R hypothetical protein complement(1469699..1470427) Streptococcus pneumoniae ATCC 700669 7328733 YP_002511414.1 CDS SPN23F_15150 NC_011900.1 1470849 1472444 R hypothetical protein complement(1470849..1472444) Streptococcus pneumoniae ATCC 700669 7328734 YP_002511415.1 CDS fms NC_011900.1 1472456 1472866 R cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+); peptide deformylase complement(1472456..1472866) Streptococcus pneumoniae ATCC 700669 7328735 YP_002511416.1 CDS SPN23F_15170 NC_011900.1 1472982 1473773 R YghU; B2989; one of eight glutathione transferase proteins from E. coli; glutathione S-transferase YghU complement(1472982..1473773) Streptococcus pneumoniae ATCC 700669 7328555 YP_002511417.1 CDS SPN23F_15180 NC_011900.1 1473786 1476482 R cation transporting ATPase complement(1473786..1476482) Streptococcus pneumoniae ATCC 700669 7328736 YP_002511418.1 CDS SPN23F_15190 NC_011900.1 1476786 1477970 D cation efflux family protein 1476786..1477970 Streptococcus pneumoniae ATCC 700669 7329471 YP_002511419.1 CDS SPN23F_15200 NC_011900.1 1478113 1479984 R ABC transporter ATP-binding protein complement(1478113..1479984) Streptococcus pneumoniae ATCC 700669 7328738 YP_002511420.1 CDS cca NC_011900.1 1479981 1481165 R catalyzes the addition and repair of the 3'-terminal CCA sequence in tRNA; these proteins belong to the CCA-adding enzyme subfamily 2 which does not have phosphohydrolase activity; tRNA CCA-pyrophosphorylase complement(1479981..1481165) Streptococcus pneumoniae ATCC 700669 7328739 YP_002511421.1 CDS dapB NC_011900.1 1481177 1481944 R catalyzes the reduction of 2,3-dihydrodipicolinate to 2,3,4,5-tetrahydrodipicolinate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate reductase complement(1481177..1481944) Streptococcus pneumoniae ATCC 700669 7329186 YP_002511422.1 CDS SPN23F_15230 NC_011900.1 1482210 1483058 R DegV family protein complement(1482210..1483058) Streptococcus pneumoniae ATCC 700669 7329222 YP_002511423.1 CDS SPN23F_15240 NC_011900.1 1483060 1483434 R hypothetical protein complement(1483060..1483434) Streptococcus pneumoniae ATCC 700669 7328740 YP_002511424.1 CDS glmM NC_011900.1 1483508 1484860 R catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; phosphoglucosamine mutase complement(1483508..1484860) Streptococcus pneumoniae ATCC 700669 7328741 YP_002511425.1 CDS SPN23F_15260 NC_011900.1 1484884 1485663 R hypothetical protein complement(1484884..1485663) Streptococcus pneumoniae ATCC 700669 7328742 YP_002511426.1 CDS SPN23F_15270 NC_011900.1 1485650 1486507 R hypothetical protein complement(1485650..1486507) Streptococcus pneumoniae ATCC 700669 7328743 YP_002511427.1 CDS SPN23F_15280 NC_011900.1 1486643 1487611 D pyridine nucleotide-disulfide oxidoreductase family protein 1486643..1487611 Streptococcus pneumoniae ATCC 700669 7328744 YP_002511428.1 CDS SPN23F_15290 NC_011900.1 1487864 1488820 R autolysin complement(1487864..1488820) Streptococcus pneumoniae ATCC 700669 7328745 YP_002511429.1 CDS hol NC_011900.1 1488824 1489156 R antiholin complement(1488824..1489156) Streptococcus pneumoniae ATCC 700669 7328746 YP_002511430.1 CDS SPN23F_15310 NC_011900.1 1489160 1489576 R holin complement(1489160..1489576) Streptococcus pneumoniae ATCC 700669 7328072 YP_002511431.1 CDS SPN23F_15320 NC_011900.1 1489586 1489849 R prophage protein complement(1489586..1489849) Streptococcus pneumoniae ATCC 700669 7328747 YP_002511432.1 CDS SPN23F_15330 NC_011900.1 1489909 1491987 R phage structural protein complement(1489909..1491987) Streptococcus pneumoniae ATCC 700669 7328748 YP_002511433.1 CDS SPN23F_15340 NC_011900.1 1491998 1497025 R platelet-binding phage protein complement(1491998..1497025) Streptococcus pneumoniae ATCC 700669 7328749 YP_002511434.1 CDS SPN23F_15350 NC_011900.1 1497027 1498508 R phage tail protein complement(1497027..1498508) Streptococcus pneumoniae ATCC 700669 7328750 YP_002511435.1 CDS SPN23F_15360 NC_011900.1 1498538 1501819 R phage minor tail protein complement(1498538..1501819) Streptococcus pneumoniae ATCC 700669 7328751 YP_002511436.1 CDS SPN23F_15370 NC_011900.1 1501812 1502381 R phage Gp15 protein complement(1501812..1502381) Streptococcus pneumoniae ATCC 700669 7328752 YP_002511437.1 CDS SPN23F_15380 NC_011900.1 1502394 1502882 R hypothetical protein complement(1502394..1502882) Streptococcus pneumoniae ATCC 700669 7328753 YP_002511438.1 CDS SPN23F_15390 NC_011900.1 1502947 1503396 R hypothetical protein complement(1502947..1503396) Streptococcus pneumoniae ATCC 700669 7328754 YP_002511439.1 CDS SPN23F_15400 NC_011900.1 1503393 1503800 R hypothetical protein complement(1503393..1503800) Streptococcus pneumoniae ATCC 700669 7328755 YP_002511440.1 CDS SPN23F_15410 NC_011900.1 1503800 1504144 R hypothetical protein complement(1503800..1504144) Streptococcus pneumoniae ATCC 700669 7328756 YP_002511441.1 CDS SPN23F_15420 NC_011900.1 1504144 1504515 R hypothetical protein complement(1504144..1504515) Streptococcus pneumoniae ATCC 700669 7328757 YP_002511442.1 CDS SPN23F_15430 NC_011900.1 1504505 1504897 R hypothetical protein complement(1504505..1504897) Streptococcus pneumoniae ATCC 700669 7328758 YP_002511443.1 CDS SPN23F_15440 NC_011900.1 1504940 1505173 R hypothetical protein complement(1504940..1505173) Streptococcus pneumoniae ATCC 700669 7328759 YP_002511444.1 CDS SPN23F_15450 NC_011900.1 1505184 1506065 R phage capsid protein complement(1505184..1506065) Streptococcus pneumoniae ATCC 700669 7328760 YP_002511445.1 CDS SPN23F_15460 NC_011900.1 1506083 1506646 R phage scaffolding protein complement(1506083..1506646) Streptococcus pneumoniae ATCC 700669 7328761 YP_002511446.1 CDS SPN23F_15470 NC_011900.1 1506785 1507936 R minor capsid protein complement(1506785..1507936) Streptococcus pneumoniae ATCC 700669 7328762 YP_002511447.1 CDS SPN23F_15490 NC_011900.1 1508139 1509707 R minor capsid protein complement(1508139..1509707) Streptococcus pneumoniae ATCC 700669 7328763 YP_002511448.1 CDS SPN23F_15500 NC_011900.1 1509720 1511030 R phage terminase large subunit complement(1509720..1511030) Streptococcus pneumoniae ATCC 700669 7328764 YP_002511449.1 CDS SPN23F_15510 NC_011900.1 1511020 1511475 R hypothetical protein complement(1511020..1511475) Streptococcus pneumoniae ATCC 700669 7328765 YP_002511450.1 CDS SPN23F_15520 NC_011900.1 1511679 1512425 R hypothetical protein complement(1511679..1512425) Streptococcus pneumoniae ATCC 700669 7328766 YP_002511451.1 CDS SPN23F_15530 NC_011900.1 1512406 1513494 R hypothetical protein complement(1512406..1513494) Streptococcus pneumoniae ATCC 700669 7328767 YP_002511452.1 CDS SPN23F_15540 NC_011900.1 1513566 1513958 R hypothetical protein complement(1513566..1513958) Streptococcus pneumoniae ATCC 700669 7328768 YP_002511453.1 CDS SPN23F_15550 NC_011900.1 1513955 1514197 R hypothetical protein complement(1513955..1514197) Streptococcus pneumoniae ATCC 700669 7328769 YP_002511454.1 CDS SPN23F_15560 NC_011900.1 1514257 1514631 R hypothetical protein complement(1514257..1514631) Streptococcus pneumoniae ATCC 700669 7328770 YP_002511455.1 CDS SPN23F_15570 NC_011900.1 1514691 1514864 R hypothetical protein complement(1514691..1514864) Streptococcus pneumoniae ATCC 700669 7328771 YP_002511456.1 CDS SPN23F_15580 NC_011900.1 1514864 1515151 R hypothetical protein complement(1514864..1515151) Streptococcus pneumoniae ATCC 700669 7328772 YP_002511457.1 CDS SPN23F_15590 NC_011900.1 1515151 1515648 R hypothetical protein complement(1515151..1515648) Streptococcus pneumoniae ATCC 700669 7328773 YP_002511458.1 CDS SPN23F_15600 NC_011900.1 1515650 1515967 R hypothetical protein complement(1515650..1515967) Streptococcus pneumoniae ATCC 700669 7328774 YP_002511459.1 CDS SPN23F_15610 NC_011900.1 1516016 1516222 R hypothetical protein complement(1516016..1516222) Streptococcus pneumoniae ATCC 700669 7328775 YP_002511460.1 CDS SPN23F_15620 NC_011900.1 1516224 1516625 R phage Holliday junction resolvase complement(1516224..1516625) Streptococcus pneumoniae ATCC 700669 7328776 YP_002511461.1 CDS SPN23F_15630 NC_011900.1 1516636 1516848 R phage protein complement(1516636..1516848) Streptococcus pneumoniae ATCC 700669 7328777 YP_002511462.1 CDS SPN23F_15640 NC_011900.1 1516865 1517602 R phage protein complement(1516865..1517602) Streptococcus pneumoniae ATCC 700669 7328778 YP_002511463.1 CDS SPN23F_15650 NC_011900.1 1517604 1518038 R phage protein complement(1517604..1518038) Streptococcus pneumoniae ATCC 700669 7328779 YP_002511464.1 CDS SPN23F_15660 NC_011900.1 1518092 1518295 R hypothetical protein complement(1518092..1518295) Streptococcus pneumoniae ATCC 700669 7328780 YP_002511465.1 CDS SPN23F_15670 NC_011900.1 1518330 1519439 R DNA methylase complement(1518330..1519439) Streptococcus pneumoniae ATCC 700669 7328781 YP_002511466.1 CDS ssb NC_011900.1 1519513 1520058 R single-strand DNA-binding protein complement(1519513..1520058) Streptococcus pneumoniae ATCC 700669 7328782 YP_002511467.1 CDS SPN23F_15700 NC_011900.1 1520246 1521238 R hypothetical protein complement(1520246..1521238) Streptococcus pneumoniae ATCC 700669 7329155 YP_002511468.1 CDS ssb1 NC_011900.1 1521241 1521948 R phage single-strand DNA binding protein complement(1521241..1521948) Streptococcus pneumoniae ATCC 700669 7328783 YP_002511469.1 CDS SPN23F_15720 NC_011900.1 1521954 1522406 R hypothetical protein complement(1521954..1522406) Streptococcus pneumoniae ATCC 700669 7329156 YP_002511470.1 CDS SPN23F_15730 NC_011900.1 1522458 1522982 R hypothetical protein complement(1522458..1522982) Streptococcus pneumoniae ATCC 700669 7328784 YP_002511471.1 CDS SPN23F_15740 NC_011900.1 1523063 1523329 R hypothetical protein complement(1523063..1523329) Streptococcus pneumoniae ATCC 700669 7328785 YP_002511472.1 CDS SPN23F_15750 NC_011900.1 1523561 1523824 R hypothetical protein complement(1523561..1523824) Streptococcus pneumoniae ATCC 700669 7328786 YP_002511473.1 CDS SPN23F_15760 NC_011900.1 1524002 1524193 R phage DNA-binding protein complement(1524002..1524193) Streptococcus pneumoniae ATCC 700669 7328787 YP_002511474.1 CDS SPN23F_15770 NC_011900.1 1524490 1524852 D DNA-binding protein 1524490..1524852 Streptococcus pneumoniae ATCC 700669 7328788 YP_002511475.1 CDS SPN23F_15780 NC_011900.1 1524874 1525254 D hypothetical protein 1524874..1525254 Streptococcus pneumoniae ATCC 700669 7328789 YP_002511476.1 CDS SPN23F_15790 NC_011900.1 1525268 1525618 D phage protein 1525268..1525618 Streptococcus pneumoniae ATCC 700669 7328790 YP_002511477.1 CDS SPN23F_15800 NC_011900.1 1525737 1526864 D phage integrase 1525737..1526864 Streptococcus pneumoniae ATCC 700669 7328791 YP_002511478.1 CDS SPN23F_15810 NC_011900.1 1526952 1527863 R hypothetical protein complement(1526952..1527863) Streptococcus pneumoniae ATCC 700669 7328792 YP_002511479.1 CDS SPN23F_15820 NC_011900.1 1527860 1528837 R hypothetical protein complement(1527860..1528837) Streptococcus pneumoniae ATCC 700669 7328793 YP_002511480.1 CDS SPN23F_15830 NC_011900.1 1528834 1529724 R hypothetical protein complement(1528834..1529724) Streptococcus pneumoniae ATCC 700669 7328794 YP_002511481.1 CDS SPN23F_15840 NC_011900.1 1529776 1530156 R endoribonuclease L-PSP family protein complement(1529776..1530156) Streptococcus pneumoniae ATCC 700669 7328795 YP_002511482.1 CDS engB NC_011900.1 1530167 1530754 R binds guanine nucleotides; in Escherichia coli depletion results in defective cell division and filamentation; in Bacillus subtilis this gene is essential; ribosome biogenesis GTP-binding protein YsxC complement(1530167..1530754) Streptococcus pneumoniae ATCC 700669 7328796 YP_002511483.1 CDS clpX NC_011900.1 1530763 1531995 R binds and unfolds substrates as part of the ClpXP protease; ATP-dependent protease ATP-binding subunit ClpX complement(1530763..1531995) Streptococcus pneumoniae ATCC 700669 7329254 YP_002511484.1 CDS SPN23F_15870 NC_011900.1 1532027 1532197 R hypothetical protein complement(1532027..1532197) Streptococcus pneumoniae ATCC 700669 7329199 YP_002511485.1 CDS dyr NC_011900.1 1532197 1532703 R dihydrofolate reductase complement(1532197..1532703) Streptococcus pneumoniae ATCC 700669 7328797 YP_002511486.1 CDS dpr NC_011900.1 1532833 1533351 R Dps-like peroxide resistance protein Dpr complement(1532833..1533351) Streptococcus pneumoniae ATCC 700669 7329249 YP_002511487.1 CDS SPN23F_15900 NC_011900.1 1533849 1535321 R exported choline-binding glycosyl hydrolase complement(1533849..1535321) Streptococcus pneumoniae ATCC 700669 7329248 YP_002511488.1 CDS tpiA NC_011900.1 1535392 1536150 R Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate; triosephosphate isomerase complement(1535392..1536150) Streptococcus pneumoniae ATCC 700669 7328798 YP_002511489.1 CDS SPN23F_15920 NC_011900.1 1536248 1536925 R DNA replication protein DnaD complement(1536248..1536925) Streptococcus pneumoniae ATCC 700669 7329180 YP_002511490.1 CDS metA NC_011900.1 1536934 1537878 R catalyzes the formation of O-succinyl-L-homoserine from succinyl-CoA and L-homoserine in methionine biosynthesis; homoserine O-succinyltransferase complement(1536934..1537878) Streptococcus pneumoniae ATCC 700669 7328799 YP_002511491.1 CDS apt NC_011900.1 1538060 1538572 R catalyzes a salvage reaction resulting in the formation of AMP which is metabolically less costly than a de novo synthesis; adenine phosphoribosyltransferase complement(1538060..1538572) Streptococcus pneumoniae ATCC 700669 7328125 YP_002511492.1 CDS SPN23F_15950 NC_011900.1 1538660 1539418 R methyltransferase complement(1538660..1539418) Streptococcus pneumoniae ATCC 700669 7328650 YP_002511493.1 CDS SPN23F_15960 NC_011900.1 1539626 1539796 D hypothetical protein 1539626..1539796 Streptococcus pneumoniae ATCC 700669 7328800 YP_002511494.1 CDS msmK NC_011900.1 1539919 1541049 R multiple sugar-binding transport ATP-binding protein complement(1539919..1541049) Streptococcus pneumoniae ATCC 700669 7328801 YP_002511495.1 CDS SPN23F_15990 NC_011900.1 1541499 1542074 R isochorismatase family protein complement(1541499..1542074) Streptococcus pneumoniae ATCC 700669 7327615 YP_002511496.1 CDS codY NC_011900.1 1542074 1542862 R CodY; DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase (By similarity). It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor; transcriptional repressor CodY complement(1542074..1542862) Streptococcus pneumoniae ATCC 700669 7328802 YP_002511497.1 CDS SPN23F_16010 NC_011900.1 1543127 1544701 R DEAD/DEAH box helicase complement(1543127..1544701) Streptococcus pneumoniae ATCC 700669 7329205 YP_002511498.1 CDS SPN23F_16020 NC_011900.1 1544900 1546126 R major facilitator superfamily protein complement(1544900..1546126) Streptococcus pneumoniae ATCC 700669 7328803 YP_002511499.1 CDS SPN23F_16030 NC_011900.1 1546319 1547635 D Involved in disulfide oxidoreductase activity and electron transport; pyridine nucleotide-disulfide oxidoreductase 1546319..1547635 Streptococcus pneumoniae ATCC 700669 7328804 YP_002511500.1 CDS SPN23F_16040 NC_011900.1 1547734 1549077 D Mur ligase family protein 1547734..1549077 Streptococcus pneumoniae ATCC 700669 7328805 YP_002511501.1 CDS SPN23F_16050 NC_011900.1 1549077 1549859 D aminotransferase 1549077..1549859 Streptococcus pneumoniae ATCC 700669 7328806 YP_002511502.1 CDS pepQ NC_011900.1 1549985 1551067 D Xaa-Pro dipeptidase 1549985..1551067 Streptococcus pneumoniae ATCC 700669 7328807 YP_002511503.1 CDS SPN23F_16070 NC_011900.1 1551060 1551263 D GNAT family acetyltransferase 1551060..1551263 Streptococcus pneumoniae ATCC 700669 7327828 YP_002511504.1 CDS SPN23F_16080 NC_011900.1 1551391 1552224 R IS3-Spn1 orf B complement(1551391..1552224) Streptococcus pneumoniae ATCC 700669 7328808 YP_002511505.1 CDS SPN23F_16100 NC_011900.1 1552959 1553420 R hypothetical protein complement(1552959..1553420) Streptococcus pneumoniae ATCC 700669 7328810 YP_002511506.1 CDS thiD NC_011900.1 1553398 1554171 R catalyzes the formation of 4-amino-2-methyl-5-diphosphomethylpyrimidine; phosphomethylpyrimidine kinase complement(1553398..1554171) Streptococcus pneumoniae ATCC 700669 7328811 YP_002511507.1 CDS truA NC_011900.1 1554161 1554910 R mediates pseudouridylation (positions 38, 39, 40) at the tRNA anticodon region which contributes to the structural stability; tRNA pseudouridine synthase A complement(1554161..1554910) Streptococcus pneumoniae ATCC 700669 7329167 YP_002511508.1 CDS SPN23F_16140 NC_011900.1 1555223 1556374 R Major Facilitator Superfamily protein complement(1555223..1556374) Streptococcus pneumoniae ATCC 700669 7327653 YP_002511509.1 CDS SPN23F_16150 NC_011900.1 1556614 1557243 R hypothetical protein complement(1556614..1557243) Streptococcus pneumoniae ATCC 700669 7328812 YP_002511510.1 CDS SPN23F_16160 NC_011900.1 1557246 1557584 R PhnA protein complement(1557246..1557584) Streptococcus pneumoniae ATCC 700669 7328813 YP_002511511.1 CDS cmk NC_011900.1 1557715 1558386 R Catalyzes the formation of (d)CDP from ATP and (d)CMP; cytidylate kinase complement(1557715..1558386) Streptococcus pneumoniae ATCC 700669 7328814 YP_002511512.1 CDS SPN23F_16180 NC_011900.1 1558395 1558871 R hypothetical protein complement(1558395..1558871) Streptococcus pneumoniae ATCC 700669 7329200 YP_002511513.1 CDS SPN23F_16190 NC_011900.1 1559013 1559129 D hypothetical protein 1559013..1559129 Streptococcus pneumoniae ATCC 700669 7328815 YP_002511514.1 CDS SPN23F_16200 NC_011900.1 1559191 1560144 R membrane glycosyl transferase complement(1559191..1560144) Streptococcus pneumoniae ATCC 700669 7328816 YP_002511515.1 CDS galE NC_011900.1 1560146 1561165 R UDP-glucose 4-epimerase complement(1560146..1561165) Streptococcus pneumoniae ATCC 700669 7328817 YP_002511516.1 CDS SPN23F_16220 NC_011900.1 1561268 1561396 R hypothetical protein complement(1561268..1561396) Streptococcus pneumoniae ATCC 700669 7328580 YP_002511517.1 CDS SPN23F_16230 NC_011900.1 1561466 1562569 R FAD dependent oxidoreductase complement(1561466..1562569) Streptococcus pneumoniae ATCC 700669 7328818 YP_002511518.1 CDS SPN23F_16240 NC_011900.1 1562586 1563383 R NIF3 (NGG1p interacting factor 3) family protein complement(1562586..1563383) Streptococcus pneumoniae ATCC 700669 7328819 YP_002511519.1 CDS SPN23F_16250 NC_011900.1 1563370 1564047 R hypothetical protein complement(1563370..1564047) Streptococcus pneumoniae ATCC 700669 7328820 YP_002511520.1 CDS SPN23F_16260 NC_011900.1 1564149 1566485 R cation-transporting ATPase complement(1564149..1566485) Streptococcus pneumoniae ATCC 700669 7328821 YP_002511521.1 CDS SPN23F_16270 NC_011900.1 1566618 1567367 D acyltransferase 1566618..1567367 Streptococcus pneumoniae ATCC 700669 7328822 YP_002511522.1 CDS cadD NC_011900.1 1567659 1568273 R cadmium resistance protein complement(1567659..1568273) Streptococcus pneumoniae ATCC 700669 7328823 YP_002511523.1 CDS rpsO NC_011900.1 1569088 1569357 R primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence; 30S ribosomal protein S15 complement(1569088..1569357) Streptococcus pneumoniae ATCC 700669 7328699 YP_002511524.1 CDS SPN23F_16300 NC_011900.1 1569498 1570127 R hypothetical protein complement(1569498..1570127) Streptococcus pneumoniae ATCC 700669 7329121 YP_002511525.1 CDS SPN23F_16310 NC_011900.1 1570365 1570565 D hypothetical protein 1570365..1570565 Streptococcus pneumoniae ATCC 700669 7328824 YP_002511526.1 CDS SPN23F_16320 NC_011900.1 1570996 1571319 D hypothetical protein 1570996..1571319 Streptococcus pneumoniae ATCC 700669 7329472 YP_002511527.1 CDS thrS NC_011900.1 1571377 1573320 D catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr); threonyl-tRNA synthetase 1571377..1573320 Streptococcus pneumoniae ATCC 700669 7328826 YP_002511528.1 CDS SPN23F_16340 NC_011900.1 1573369 1574343 R sensor histidine kinase protein complement(1573369..1574343) Streptococcus pneumoniae ATCC 700669 7329174 YP_002511529.1 CDS SPN23F_16350 NC_011900.1 1574336 1575013 R response regulator protein complement(1574336..1575013) Streptococcus pneumoniae ATCC 700669 7328827 YP_002511530.1 CDS SPN23F_16360 NC_011900.1 1575169 1576242 D hypothetical protein 1575169..1576242 Streptococcus pneumoniae ATCC 700669 7328828 YP_002511531.1 CDS SPN23F_16370 NC_011900.1 1576703 1577140 R transcriptional regulator protein complement(1576703..1577140) Streptococcus pneumoniae ATCC 700669 7328829 YP_002511532.1 CDS SPN23F_16380 NC_011900.1 1577216 1578058 R metallophosphoesterase protein complement(1577216..1578058) Streptococcus pneumoniae ATCC 700669 7328830 YP_002511533.1 CDS scaR NC_011900.1 1578170 1578820 D metal-dependent transcriptional regulator 1578170..1578820 Streptococcus pneumoniae ATCC 700669 7328831 YP_002511534.1 CDS SPN23F_16410 NC_011900.1 1579017 1579664 D hypothetical protein 1579017..1579664 Streptococcus pneumoniae ATCC 700669 7329131 YP_002511535.1 CDS SPN23F_16420 NC_011900.1 1579795 1580208 D hypothetical protein 1579795..1580208 Streptococcus pneumoniae ATCC 700669 7328832 YP_002511536.1 CDS SPN23F_16450 NC_011900.1 1580679 1581122 R hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr); possible defense mechanism against a harmful effect of D-tyrosine; D-tyrosyl-tRNA(Tyr) deacylase complement(1580679..1581122) Streptococcus pneumoniae ATCC 700669 7328834 YP_002511537.1 CDS relA NC_011900.1 1581152 1583374 R GTP pyrophosphokinase complement(1581152..1583374) Streptococcus pneumoniae ATCC 700669 7328835 YP_002511538.1 CDS SPN23F_16480 NC_011900.1 1584370 1584999 D metallo-beta-lactamase superfamily protein 1584370..1584999 Streptococcus pneumoniae ATCC 700669 7327449 YP_002511539.1 CDS pepO NC_011900.1 1585122 1587014 R endopeptidase O complement(1585122..1587014) Streptococcus pneumoniae ATCC 700669 7328836 YP_002511540.1 CDS mtsB NC_011900.1 1587305 1588027 D metal cation ABC transporter ATP-binding protein 1587305..1588027 Streptococcus pneumoniae ATCC 700669 7327827 YP_002511541.1 CDS mtsC NC_011900.1 1588024 1588872 D metal cation ABC transporter membrane protein 1588024..1588872 Streptococcus pneumoniae ATCC 700669 7328389 YP_002511542.1 CDS mtsA NC_011900.1 1588904 1589833 D metal ABC transporter substrate-binding lipoprotein precursor 1588904..1589833 Streptococcus pneumoniae ATCC 700669 7328390 YP_002511543.1 CDS tpx NC_011900.1 1589956 1590447 D antioxidant activity; thioredoxin-dependent thiol peroxidase; forms homodimers in solution; shows substrate specificity to alkyl hydroperoxides; periplasmic protein; thiol peroxidase 1589956..1590447 Streptococcus pneumoniae ATCC 700669 7328388 YP_002511544.1 CDS SPN23F_16540 NC_011900.1 1590543 1593251 R ABC transporter permease complement(1590543..1593251) Streptococcus pneumoniae ATCC 700669 7327580 YP_002511545.1 CDS SPN23F_16550 NC_011900.1 1593253 1593954 R ABC transporter ATP-binding protein complement(1593253..1593954) Streptococcus pneumoniae ATCC 700669 7328837 YP_002511546.1 CDS SPN23F_16560 NC_011900.1 1594204 1596615 R hypothetical protein complement(1594204..1596615) Streptococcus pneumoniae ATCC 700669 7328838 YP_002511547.1 CDS gpmA NC_011900.1 1596668 1597360 R 2,3-bisphosphoglycerate-dependent; catalyzes the interconversion of 2-phosphoglycerate to 3-phosphoglycerate; phosphoglyceromutase complement(1596668..1597360) Streptococcus pneumoniae ATCC 700669 7328839 YP_002511548.1 CDS SPN23F_16580 NC_011900.1 1597411 1597599 R hypothetical protein complement(1597411..1597599) Streptococcus pneumoniae ATCC 700669 7328619 YP_002511549.1 CDS SPN23F_16590 NC_011900.1 1597895 1598275 R integral membrane protein complement(1597895..1598275) Streptococcus pneumoniae ATCC 700669 7328840 YP_002511550.1 CDS ileS NC_011900.1 1598678 1601470 R IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase family type 1 subfamily; some organisms carry two different copies of this enzyme; isoleucyl-tRNA synthetase complement(1598678..1601470) Streptococcus pneumoniae ATCC 700669 7328841 YP_002511551.1 CDS SPN23F_16620 NC_011900.1 1601818 1602606 R cell-division protein DivIVA complement(1601818..1602606) Streptococcus pneumoniae ATCC 700669 7329473 YP_002511552.1 CDS SPN23F_16630 NC_011900.1 1602615 1603400 R hypothetical protein complement(1602615..1603400) Streptococcus pneumoniae ATCC 700669 7328842 YP_002511553.1 CDS SPN23F_16640 NC_011900.1 1603397 1603660 R hypothetical protein complement(1603397..1603660) Streptococcus pneumoniae ATCC 700669 7328843 YP_002511554.1 CDS SPN23F_16650 NC_011900.1 1603660 1604199 R hypothetical protein complement(1603660..1604199) Streptococcus pneumoniae ATCC 700669 7328844 YP_002511555.1 CDS SPN23F_16660 NC_011900.1 1604209 1604880 R hypothetical protein complement(1604209..1604880) Streptococcus pneumoniae ATCC 700669 7328845 YP_002511556.1 CDS ftsZ NC_011900.1 1604885 1606144 R GTPase; similar structure to tubulin; forms ring-shaped polymers at the site of cell division; other proteins such as FtsA, ZipA, and ZapA, interact with and regulate FtsZ function; cell division protein FtsZ complement(1604885..1606144) Streptococcus pneumoniae ATCC 700669 7328846 YP_002511557.1 CDS ftsA NC_011900.1 1606161 1607534 R cell division protein complement(1606161..1607534) Streptococcus pneumoniae ATCC 700669 7328574 YP_002511558.1 CDS SPN23F_16690 NC_011900.1 1607753 1608457 R hypothetical protein complement(1607753..1608457) Streptococcus pneumoniae ATCC 700669 7328567 YP_002511559.1 CDS SPN23F_16700 NC_011900.1 1608548 1609159 R MutT/NUDIX hydrolase family protein complement(1608548..1609159) Streptococcus pneumoniae ATCC 700669 7328847 YP_002511560.1 CDS murF NC_011900.1 1609146 1610519 R UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase complement(1609146..1610519) Streptococcus pneumoniae ATCC 700669 7328848 YP_002511561.1 CDS ddl NC_011900.1 1610603 1611646 R D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli; D-alanyl-alanine synthetase A complement(1610603..1611646) Streptococcus pneumoniae ATCC 700669 7328396 YP_002511562.1 CDS recR NC_011900.1 1611822 1612418 R involved in a recombinational process of DNA repair, independent of the recBC complex; recombination protein RecR complement(1611822..1612418) Streptococcus pneumoniae ATCC 700669 7329223 YP_002511563.1 CDS penA NC_011900.1 1612429 1614471 R penicillin-binding protein 2b complement(1612429..1614471) Streptococcus pneumoniae ATCC 700669 7327447 YP_002511564.1 CDS SPN23F_16750 NC_011900.1 1614680 1615531 D transcription regulator 1614680..1615531 Streptococcus pneumoniae ATCC 700669 7327822 YP_002511565.1 CDS SPN23F_16760 NC_011900.1 1615547 1616431 R ROK family protein complement(1615547..1616431) Streptococcus pneumoniae ATCC 700669 7328849 YP_002511566.1 CDS nanH NC_011900.1 1616449 1617366 R N-acetylneuraminate lyase complement(1616449..1617366) Streptococcus pneumoniae ATCC 700669 7328850 YP_002511567.1 CDS SPN23F_16780 NC_011900.1 1617535 1618179 R hypothetical protein complement(1617535..1618179) Streptococcus pneumoniae ATCC 700669 7328418 YP_002511568.1 CDS SPN23F_16790 NC_011900.1 1618466 1618810 R hypothetical protein complement(1618466..1618810) Streptococcus pneumoniae ATCC 700669 7328851 YP_002511569.1 CDS SPN23F_16800 NC_011900.1 1618907 1619359 R hypothetical protein complement(1618907..1619359) Streptococcus pneumoniae ATCC 700669 7328852 YP_002511570.1 CDS SPN23F_16810 NC_011900.1 1619631 1620470 R transport system permease complement(1619631..1620470) Streptococcus pneumoniae ATCC 700669 7328853 YP_002511571.1 CDS SPN23F_16820 NC_011900.1 1620486 1621382 R transport system permease complement(1620486..1621382) Streptococcus pneumoniae ATCC 700669 7328854 YP_002511572.1 CDS SPN23F_16830 NC_011900.1 1621605 1622933 R extracellular solute-binding lipoprotein complement(1621605..1622933) Streptococcus pneumoniae ATCC 700669 7328855 YP_002511573.1 CDS SPN23F_16840 NC_011900.1 1623058 1624575 R sugar phosphotransferase system (PTS), IIBC component complement(1623058..1624575) Streptococcus pneumoniae ATCC 700669 7328856 YP_002511574.1 CDS SPN23F_16850 NC_011900.1 1624594 1625292 R Converts N-acetylmannosamine-6-phosphate to N-acetylglucosamine-6-phosphate; N-acetylmannosamine-6-phosphate 2-epimerase complement(1624594..1625292) Streptococcus pneumoniae ATCC 700669 7328857 YP_002511575.1 CDS SPN23F_16860 NC_011900.1 1625466 1626569 R oxidoreductase complement(1625466..1626569) Streptococcus pneumoniae ATCC 700669 7328858 YP_002511576.1 CDS nanB NC_011900.1 1626581 1628674 R sialidase B precursor (neuraminidase B) complement(1626581..1628674) Streptococcus pneumoniae ATCC 700669 7328859 YP_002511577.1 CDS SPN23F_16880 NC_011900.1 1628692 1629525 R ABC transporter permease complement(1628692..1629525) Streptococcus pneumoniae ATCC 700669 7328416 YP_002511578.1 CDS SPN23F_16890 NC_011900.1 1629525 1630409 R ABC transporter permease complement(1629525..1630409) Streptococcus pneumoniae ATCC 700669 7328860 YP_002511579.1 CDS SPN23F_16900 NC_011900.1 1630488 1631825 R ABC transporter substrate-binding protein complement(1630488..1631825) Streptococcus pneumoniae ATCC 700669 7328060 YP_002511580.1 CDS SPN23F_16910 NC_011900.1 1631844 1632296 R hypothetical protein complement(1631844..1632296) Streptococcus pneumoniae ATCC 700669 7329488 YP_002511581.1 CDS nanA NC_011900.1 1633310 1636207 R sialidase A (neuraminidase A) complement(1633310..1636207) Streptococcus pneumoniae ATCC 700669 7329489 YP_002511582.1 CDS SPN23F_16930 NC_011900.1 1636495 1636722 R hypothetical protein complement(1636495..1636722) Streptococcus pneumoniae ATCC 700669 7328415 YP_002511583.1 CDS SPN23F_16950 NC_011900.1 1637752 1638732 R acetyl xylan esterase (AXE1) family protein complement(1637752..1638732) Streptococcus pneumoniae ATCC 700669 7329490 YP_002511584.1 CDS recG NC_011900.1 1639049 1641064 R catalyzes branch migration in Holliday junction intermediates; ATP-dependent DNA helicase RecG complement(1639049..1641064) Streptococcus pneumoniae ATCC 700669 7329491 YP_002511585.1 CDS alr NC_011900.1 1641083 1642186 R converts L-alanine to D-alanine which is used in cell wall biosynthesis; binds one pyridoxal phosphate per monomer; forms a homodimer; alanine racemase complement(1641083..1642186) Streptococcus pneumoniae ATCC 700669 7327444 YP_002511586.1 CDS acpS NC_011900.1 1642176 1642538 R Catalyzes the formation of holo-ACP, which mediates the essential transfer of acyl fatty acid intermediates during the biosynthesis of fatty acids and lipids; 4'-phosphopantetheinyl transferase complement(1642176..1642538) Streptococcus pneumoniae ATCC 700669 7328648 YP_002511587.1 CDS aroF NC_011900.1 1642583 1643614 R catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, phenylalanine sensitive; phospho-2-dehydro-3-deoxyheptonate aldolase complement(1642583..1643614) Streptococcus pneumoniae ATCC 700669 7328632 YP_002511588.1 CDS aroF1 NC_011900.1 1643616 1644647 R catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, tyrosine sensitive; phospho-2-dehydro-3-deoxyheptonate aldolase complement(1643616..1644647) Streptococcus pneumoniae ATCC 700669 7328663 YP_002511589.1 CDS secA NC_011900.1 1644728 1647241 R functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond SecA1; SecA2 is not essential and seems to play a role in secretion of a subset of proteins; preprotein translocase subunit SecA complement(1644728..1647241) Streptococcus pneumoniae ATCC 700669 7328664 YP_002511590.1 CDS SPN23F_17020 NC_011900.1 1647387 1647674 R hypothetical protein complement(1647387..1647674) Streptococcus pneumoniae ATCC 700669 7329140 YP_002511591.1 CDS SPN23F_17030 NC_011900.1 1647702 1648334 R ABC transporter ATP-binding protein complement(1647702..1648334) Streptococcus pneumoniae ATCC 700669 7329492 YP_002511592.1 CDS SPN23F_17040 NC_011900.1 1648338 1648979 R hypothetical protein complement(1648338..1648979) Streptococcus pneumoniae ATCC 700669 7329493 YP_002511593.1 CDS SPN23F_17050 NC_011900.1 1648972 1649763 R hypothetical protein complement(1648972..1649763) Streptococcus pneumoniae ATCC 700669 7329494 YP_002511594.1 CDS SPN23F_17060 NC_011900.1 1649785 1650177 R hypothetical protein complement(1649785..1650177) Streptococcus pneumoniae ATCC 700669 7329495 YP_002511595.1 CDS SPN23F_17070 NC_011900.1 1650504 1651355 D DNA-binding protein 1650504..1651355 Streptococcus pneumoniae ATCC 700669 7329496 YP_002511596.1 CDS SPN23F_17080 NC_011900.1 1651587 1651937 R hypothetical protein complement(1651587..1651937) Streptococcus pneumoniae ATCC 700669 7329497 YP_002511597.1 CDS SPN23F_17090 NC_011900.1 1652077 1652412 R hypothetical protein complement(1652077..1652412) Streptococcus pneumoniae ATCC 700669 7329498 YP_002511598.1 CDS engA NC_011900.1 1652500 1653810 R EngA; essential Neisserial GTPase; synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains; GTP-binding protein EngA complement(1652500..1653810) Streptococcus pneumoniae ATCC 700669 7329499 YP_002511599.1 CDS nfsA NC_011900.1 1653824 1654537 R oxygen-insensitive NADPH nitroreductase complement(1653824..1654537) Streptococcus pneumoniae ATCC 700669 7329253 YP_002511600.1 CDS dnaI NC_011900.1 1654534 1655430 R Primosomal protein that may act to load helicase DnaC during DNA replication; primosomal protein DnaI complement(1654534..1655430) Streptococcus pneumoniae ATCC 700669 7328420 YP_002511601.1 CDS dnaB NC_011900.1 1655431 1656600 R replication initiation and membrane attachment protein complement(1655431..1656600) Streptococcus pneumoniae ATCC 700669 7329243 YP_002511602.1 CDS nrdR NC_011900.1 1656601 1657074 R NrdR family transcriptional regulator complement(1656601..1657074) Streptococcus pneumoniae ATCC 700669 7329238 YP_002511603.1 CDS SPN23F_17150 NC_011900.1 1657214 1657579 D GntR family transcriptional regulator 1657214..1657579 Streptococcus pneumoniae ATCC 700669 7329500 YP_002511604.1 CDS SPN23F_17160 NC_011900.1 1657584 1658279 D ABC transporter ATP-binding protein 1657584..1658279 Streptococcus pneumoniae ATCC 700669 7329501 YP_002511605.1 CDS SPN23F_17170 NC_011900.1 1658296 1659063 D hypothetical protein 1658296..1659063 Streptococcus pneumoniae ATCC 700669 7329502 YP_002511606.1 CDS SPN23F_17180 NC_011900.1 1659416 1660615 R hypothetical protein complement(1659416..1660615) Streptococcus pneumoniae ATCC 700669 7329503 YP_002511607.1 CDS SPN23F_17190 NC_011900.1 1660612 1661505 R ABC transporter ATP-binding protein complement(1660612..1661505) Streptococcus pneumoniae ATCC 700669 7329504 YP_002511608.1 CDS SPN23F_17210 NC_011900.1 1662815 1663432 D hypothetical protein 1662815..1663432 Streptococcus pneumoniae ATCC 700669 7329505 YP_002511609.1 CDS scrK NC_011900.1 1663752 1664639 R fructokinase complement(1663752..1664639) Streptococcus pneumoniae ATCC 700669 7329506 YP_002511610.1 CDS scrA NC_011900.1 1664788 1666671 R sucrose-specific phosphotransferase system (PTS), IIABC component complement(1664788..1666671) Streptococcus pneumoniae ATCC 700669 7329136 YP_002511611.1 CDS scrB NC_011900.1 1667048 1668502 D sucrose-6-phosphate hydrolase 1667048..1668502 Streptococcus pneumoniae ATCC 700669 7329134 YP_002511612.1 CDS scrR NC_011900.1 1668483 1669448 D sucrose operon repressor 1668483..1669448 Streptococcus pneumoniae ATCC 700669 7329135 YP_002511613.1 CDS mvaA NC_011900.1 1669483 1670757 R 3-hydroxy-3-methylglutaryl-coenzyme A reductase complement(1669483..1670757) Streptococcus pneumoniae ATCC 700669 7329137 YP_002511614.1 CDS mvaS NC_011900.1 1670757 1671929 R 3-hydroxy-3-methylglutaryl coenzyme A synthase complement(1670757..1671929) Streptococcus pneumoniae ATCC 700669 7328406 YP_002511615.1 CDS SPN23F_17290 NC_011900.1 1672060 1672308 R hypothetical protein complement(1672060..1672308) Streptococcus pneumoniae ATCC 700669 7328410 YP_002511616.1 CDS SPN23F_17330 NC_011900.1 1673063 1673398 R hypothetical protein complement(1673063..1673398) Streptococcus pneumoniae ATCC 700669 7329508 YP_002511617.1 CDS SPN23F_17340 NC_011900.1 1673514 1674272 R hypothetical protein complement(1673514..1674272) Streptococcus pneumoniae ATCC 700669 7329509 YP_002511618.1 CDS stk1 NC_011900.1 1674387 1676366 R serine/threonine-protein kinase complement(1674387..1676366) Streptococcus pneumoniae ATCC 700669 7329510 YP_002511619.1 CDS SPN23F_17360 NC_011900.1 1676363 1677103 R protein phosphatase complement(1676363..1677103) Streptococcus pneumoniae ATCC 700669 7329157 YP_002511620.1 CDS SPN23F_17370 NC_011900.1 1677118 1678431 R ribosomal RNA small subunit methyltransferase complement(1677118..1678431) Streptococcus pneumoniae ATCC 700669 7329511 YP_002511621.1 CDS fmt NC_011900.1 1678424 1679359 R modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet) which is important in translation initiation; inactivation of this gene in Escherichia coli severely impairs growth; methionyl-tRNA formyltransferase complement(1678424..1679359) Streptococcus pneumoniae ATCC 700669 7329512 YP_002511622.1 CDS priA NC_011900.1 1679372 1681768 R binding of PriA to forked DNA starts the assembly of the primosome, also possesses 3'-5' helicase activity; primosome assembly protein PriA complement(1679372..1681768) Streptococcus pneumoniae ATCC 700669 7328556 YP_002511623.1 CDS rpoZ NC_011900.1 1681834 1682148 R Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits; DNA-directed RNA polymerase subunit omega complement(1681834..1682148) Streptococcus pneumoniae ATCC 700669 7327875 YP_002511624.1 CDS gmk NC_011900.1 1682173 1682799 R Essential for recycling GMP and indirectly, cGMP; guanylate kinase complement(1682173..1682799) Streptococcus pneumoniae ATCC 700669 7329108 YP_002511625.1 CDS SPN23F_17420 NC_011900.1 1682929 1684542 R hypothetical protein complement(1682929..1684542) Streptococcus pneumoniae ATCC 700669 7328616 YP_002511626.1 CDS SPN23F_17430 NC_011900.1 1684612 1684902 R site-specific recombinase complement(1684612..1684902) Streptococcus pneumoniae ATCC 700669 7329513 YP_002511627.1 CDS SPN23F_17440 NC_011900.1 1685025 1685783 R Unique to this genome and apparently part of an integrated element.; hypothetical protein complement(1685025..1685783) Streptococcus pneumoniae ATCC 700669 7329514 YP_002511628.1 CDS SPN23F_17450 NC_011900.1 1685799 1685939 R May form N-term signal sequence for downstream gene?; hypothetical protein complement(1685799..1685939) Streptococcus pneumoniae ATCC 700669 7329515 YP_002511629.1 CDS SPN23F_17460 NC_011900.1 1686091 1686264 R hypothetical protein complement(1686091..1686264) Streptococcus pneumoniae ATCC 700669 7329516 YP_002511630.1 CDS SPN23F_17490 NC_011900.1 1687632 1688729 R hypothetical protein complement(1687632..1688729) Streptococcus pneumoniae ATCC 700669 7329519 YP_002511631.1 CDS SPN23F_17500 NC_011900.1 1688739 1689479 R methyltransferase complement(1688739..1689479) Streptococcus pneumoniae ATCC 700669 7329520 YP_002511632.1 CDS SPN23F_17510 NC_011900.1 1689799 1690152 R hypothetical protein complement(1689799..1690152) Streptococcus pneumoniae ATCC 700669 7329521 YP_002511633.1 CDS SPN23F_17520 NC_011900.1 1690165 1690665 R isochorismatase complement(1690165..1690665) Streptococcus pneumoniae ATCC 700669 7329522 YP_002511634.1 CDS SPN23F_17530 NC_011900.1 1690666 1691259 R hypothetical protein complement(1690666..1691259) Streptococcus pneumoniae ATCC 700669 7329523 YP_002511635.1 CDS nadD NC_011900.1 1691259 1691888 R transfers an adenyl group from ATP to NaMN to form nicotinic acid adenine dinucleotide (NaAD) which is then converted to the ubiquitous compound NAD by NAD synthetase; essential enzyme in bacteria; nicotinic acid mononucleotide adenylyltransferase complement(1691259..1691888) Streptococcus pneumoniae ATCC 700669 7329524 YP_002511636.1 CDS SPN23F_17550 NC_011900.1 1691940 1692251 R hypothetical protein complement(1691940..1692251) Streptococcus pneumoniae ATCC 700669 7329525 YP_002511637.1 CDS SPN23F_17560 NC_011900.1 1692451 1693557 R in Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis; GTP-binding protein YqeH complement(1692451..1693557) Streptococcus pneumoniae ATCC 700669 7329526 YP_002511638.1 CDS SPN23F_17570 NC_011900.1 1693560 1694087 R hydrolase complement(1693560..1694087) Streptococcus pneumoniae ATCC 700669 7329527 YP_002511639.1 CDS SPN23F_17580 NC_011900.1 1694102 1695010 R CorA-like Mg2+ transporter protein complement(1694102..1695010) Streptococcus pneumoniae ATCC 700669 7329528 YP_002511640.1 CDS SPN23F_17590 NC_011900.1 1695067 1695627 R mechanosensitive ion channel protein complement(1695067..1695627) Streptococcus pneumoniae ATCC 700669 7329529 YP_002511641.1 CDS SPN23F_17600 NC_011900.1 1695831 1696019 D sodium:dicarboxylate symporter family protein 1695831..1696019 Streptococcus pneumoniae ATCC 700669 7329530 YP_002511642.1 CDS SPN23F_17610 NC_011900.1 1696016 1696975 D involved in the import of serine and threonine coupled with the import of sodium; serine/threonine transporter SstT 1696016..1696975 Streptococcus pneumoniae ATCC 700669 7329531 YP_002511643.1 CDS SPN23F_17620 NC_011900.1 1697043 1697996 D hypothetical protein 1697043..1697996 Streptococcus pneumoniae ATCC 700669 7329532 YP_002511644.1 CDS SPN23F_17630 NC_011900.1 1698019 1698621 R Mostly made up of 11 x FEVVDRTDEVSSKHR tandem repeat. No good RBS.; hypothetical protein complement(1698019..1698621) Streptococcus pneumoniae ATCC 700669 7329533 YP_002511645.1 CDS SPN23F_17640 NC_011900.1 1698682 1698906 R hypothetical protein complement(1698682..1698906) Streptococcus pneumoniae ATCC 700669 7329534 YP_002511646.1 CDS SPN23F_17650 NC_011900.1 1698911 1699090 R hypothetical protein complement(1698911..1699090) Streptococcus pneumoniae ATCC 700669 7329535 YP_002511647.1 CDS SPN23F_17660 NC_011900.1 1699092 1700429 R hypothetical protein complement(1699092..1700429) Streptococcus pneumoniae ATCC 700669 7329536 YP_002511648.1 CDS SPN23F_17670 NC_011900.1 1700422 1701933 R glycosyl transferase complement(1700422..1701933) Streptococcus pneumoniae ATCC 700669 7329537 YP_002511649.1 CDS SPN23F_17680 NC_011900.1 1701945 1704317 R functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; in some organisms, especially gram positive pathogens, have paralogs that have been found to be nonessential but do function in secretion of a subset of exported proteins; preprotein translocase subunit SecA complement(1701945..1704317) Streptococcus pneumoniae ATCC 700669 7329538 YP_002511650.1 CDS SPN23F_17690 NC_011900.1 1704310 1704750 R hypothetical protein complement(1704310..1704750) Streptococcus pneumoniae ATCC 700669 7329539 YP_002511651.1 CDS SPN23F_17700 NC_011900.1 1704747 1706282 R hypothetical protein complement(1704747..1706282) Streptococcus pneumoniae ATCC 700669 7329540 YP_002511652.1 CDS SPN23F_17710 NC_011900.1 1706266 1707846 R hypothetical protein complement(1706266..1707846) Streptococcus pneumoniae ATCC 700669 7329541 YP_002511653.1 CDS secY NC_011900.1 1707856 1709073 R forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase; preprotein translocase subunit SecY complement(1707856..1709073) Streptococcus pneumoniae ATCC 700669 7329542 YP_002511654.1 CDS SPN23F_17730 NC_011900.1 1709130 1710035 R glycosyltransferase complement(1709130..1710035) Streptococcus pneumoniae ATCC 700669 7329543 YP_002511655.1 CDS SPN23F_17740 NC_011900.1 1710035 1711231 R glycosyltransferase complement(1710035..1711231) Streptococcus pneumoniae ATCC 700669 7329544 YP_002511656.1 CDS SPN23F_17750 NC_011900.1 1711240 1712460 R glycosyltransferase complement(1711240..1712460) Streptococcus pneumoniae ATCC 700669 7329545 YP_002511657.1 CDS SPN23F_17760 NC_011900.1 1712485 1713369 R glycosyl transferase complement(1712485..1713369) Streptococcus pneumoniae ATCC 700669 7329546 YP_002511658.1 CDS SPN23F_17770 NC_011900.1 1713366 1715819 R glycosyltransferase complement(1713366..1715819) Streptococcus pneumoniae ATCC 700669 7329547 YP_002511659.1 CDS SPN23F_17780 NC_011900.1 1715902 1716867 R hypothetical protein complement(1715902..1716867) Streptococcus pneumoniae ATCC 700669 7329548 YP_002511660.1 CDS SPN23F_17790 NC_011900.1 1716896 1717486 R glycosyltransferase complement(1716896..1717486) Streptococcus pneumoniae ATCC 700669 7329549 YP_002511661.1 CDS SPN23F_17800 NC_011900.1 1717777 1718991 R glycosyltransferase complement(1717777..1718991) Streptococcus pneumoniae ATCC 700669 7329550 YP_002511662.1 CDS SPN23F_17810 NC_011900.1 1719298 1721382 R glycosyl transferase complement(1719298..1721382) Streptococcus pneumoniae ATCC 700669 7329551 YP_002511663.1 CDS psrP NC_011900.1 1721443 1734744 R cell wall surface anchored protein complement(1721443..1734744) Streptococcus pneumoniae ATCC 700669 7329552 YP_002511664.1 CDS SPN23F_17840 NC_011900.1 1735116 1735595 R match to Transposase_14 (PF01710); transposase complement(1735116..1735595) Streptococcus pneumoniae ATCC 700669 7327884 YP_002511665.1 CDS SPN23F_17850 NC_011900.1 1735974 1736354 D match to MarR (PF01047); MarR-family transcriptional regulator 1735974..1736354 Streptococcus pneumoniae ATCC 700669 7329553 YP_002511666.1 CDS SPN23F_17860 NC_011900.1 1736453 1736674 D hypothetical protein 1736453..1736674 Streptococcus pneumoniae ATCC 700669 7329554 YP_002511667.1 CDS SPN23F_17870 NC_011900.1 1736691 1737005 D thioredoxin 1736691..1737005 Streptococcus pneumoniae ATCC 700669 7329555 YP_002511668.1 CDS SPN23F_17880 NC_011900.1 1737312 1737845 D NADPH-dependent; catalyzes the reduction of 7-cyano-7-deazaguanine to 7-aminomethyl-7-deazaguanine in queuosine biosynthesis; 7-cyano-7-deazaguanine reductase 1737312..1737845 Streptococcus pneumoniae ATCC 700669 7329556 YP_002511669.1 CDS SPN23F_17890 NC_011900.1 1737907 1738164 D hypothetical protein 1737907..1738164 Streptococcus pneumoniae ATCC 700669 7329557 YP_002511670.1 CDS aqpZ NC_011900.1 1738189 1738857 R aquaporin Z complement(1738189..1738857) Streptococcus pneumoniae ATCC 700669 7329558 YP_002511671.1 CDS SPN23F_17910 NC_011900.1 1738968 1739759 R hypothetical protein complement(1738968..1739759) Streptococcus pneumoniae ATCC 700669 7328651 YP_002511672.1 CDS SPN23F_17920 NC_011900.1 1739827 1739982 R hypothetical protein complement(1739827..1739982) Streptococcus pneumoniae ATCC 700669 7329559 YP_002511673.1 CDS SPN23F_17930 NC_011900.1 1740006 1741802 R oligopeptidase complement(1740006..1741802) Streptococcus pneumoniae ATCC 700669 7329560 YP_002511674.1 CDS SPN23F_17940 NC_011900.1 1741813 1742556 R in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA; cells lacking this function can grow, but are outcompeted by wild-type; SAM-dependent m(3)U1498 methyltransferase; 16S ribosomal RNA methyltransferase RsmE complement(1741813..1742556) Streptococcus pneumoniae ATCC 700669 7329561 YP_002511675.1 CDS prmA NC_011900.1 1742558 1743508 R methylates ribosomal protein L11 at multiple amino acid positions; mutations of these genes in Escherichia coli or Thermus thermophilus has no apparent phenotype; ribosomal protein L11 methyltransferase complement(1742558..1743508) Streptococcus pneumoniae ATCC 700669 7329562 YP_002511676.1 CDS SPN23F_17960 NC_011900.1 1743523 1744539 R otitis media-associated p41 complement(1743523..1744539) Streptococcus pneumoniae ATCC 700669 7329563 YP_002511677.1 CDS SPN23F_17970 NC_011900.1 1744590 1746734 R hypothetical protein complement(1744590..1746734) Streptococcus pneumoniae ATCC 700669 7329564 YP_002511678.1 CDS SPN23F_17980 NC_011900.1 1746835 1747869 R ATPase complement(1746835..1747869) Streptococcus pneumoniae ATCC 700669 7329565 YP_002511679.1 CDS SPN23F_18000 NC_011900.1 1748118 1749206 R peptidase complement(1748118..1749206) Streptococcus pneumoniae ATCC 700669 7329566 YP_002511680.1 CDS SPN23F_18010 NC_011900.1 1749225 1749695 R hypothetical protein complement(1749225..1749695) Streptococcus pneumoniae ATCC 700669 7328141 YP_002511681.1 CDS SPN23F_18020 NC_011900.1 1749986 1750438 R phage-like protein complement(1749986..1750438) Streptococcus pneumoniae ATCC 700669 7329341 YP_002511682.1 CDS SPN23F_18030 NC_011900.1 1750791 1750970 R hypothetical protein complement(1750791..1750970) Streptococcus pneumoniae ATCC 700669 7329342 YP_002511683.1 CDS SPN23F_18040 NC_011900.1 1751135 1751374 R hypothetical protein complement(1751135..1751374) Streptococcus pneumoniae ATCC 700669 7329343 YP_002511684.1 CDS SPN23F_18050 NC_011900.1 1751644 1752915 D recombination factor protein RarA 1751644..1752915 Streptococcus pneumoniae ATCC 700669 7329344 YP_002511685.1 CDS SPN23F_18060 NC_011900.1 1753460 1754779 R beta-fructofuranosidase complement(1753460..1754779) Streptococcus pneumoniae ATCC 700669 7327621 YP_002511686.1 CDS SPN23F_18070 NC_011900.1 1754789 1756405 R extracellular solute-binding protein complement(1754789..1756405) Streptococcus pneumoniae ATCC 700669 7329346 YP_002511687.1 CDS SPN23F_18080 NC_011900.1 1756434 1757324 R binding-protein-dependent transport system membrane protein complement(1756434..1757324) Streptococcus pneumoniae ATCC 700669 7329347 YP_002511688.1 CDS SPN23F_18090 NC_011900.1 1757335 1758252 R binding-protein-dependent transport system membrane protein complement(1757335..1758252) Streptococcus pneumoniae ATCC 700669 7329348 YP_002511689.1 CDS SPN23F_18100 NC_011900.1 1758403 1759404 R LacI family transcriptional regulator complement(1758403..1759404) Streptococcus pneumoniae ATCC 700669 7329349 YP_002511690.1 CDS SPN23F_18110 NC_011900.1 1759766 1761247 R Mga-like regulatory protein complement(1759766..1761247) Streptococcus pneumoniae ATCC 700669 7329350 YP_002511691.1 CDS SPN23F_18120 NC_011900.1 1761690 1761854 D transglycosylase 1761690..1761854 Streptococcus pneumoniae ATCC 700669 7329351 YP_002511692.1 CDS SPN23F_18130 NC_011900.1 1761938 1762504 D hypothetical protein 1761938..1762504 Streptococcus pneumoniae ATCC 700669 7329352 YP_002511693.1 CDS SPN23F_18140 NC_011900.1 1762516 1762686 D hypothetical protein 1762516..1762686 Streptococcus pneumoniae ATCC 700669 7329353 YP_002511694.1 CDS SPN23F_18150 NC_011900.1 1762725 1763333 D hypothetical protein 1762725..1763333 Streptococcus pneumoniae ATCC 700669 7329354 YP_002511696.1 CDS SPN23F_18180 NC_011900.1 1764824 1765594 R hypothetical protein complement(1764824..1765594) Streptococcus pneumoniae ATCC 700669 7329356 YP_002511697.1 CDS SPN23F_18190 NC_011900.1 1765609 1766457 R hypothetical protein complement(1765609..1766457) Streptococcus pneumoniae ATCC 700669 7329357 YP_002511698.1 CDS SPN23F_18200 NC_011900.1 1766454 1767929 R can hydrolyze p-nitrophenyl sulfate; contains a specific cysteine that is converted into C{alpha]-formylglycine upon activation with the anaerobic sulfatase-maturase; arylsulfatase complement(1766454..1767929) Streptococcus pneumoniae ATCC 700669 7329358 YP_002511699.1 CDS SPN23F_18210 NC_011900.1 1768252 1769607 R sugar phosphotransferase system (PTS), IIC component complement(1768252..1769607) Streptococcus pneumoniae ATCC 700669 7329359 YP_002511700.1 CDS SPN23F_18220 NC_011900.1 1769617 1769934 R lactose/cellobiose-specific phosphotransferase system (PTS), IIA component complement(1769617..1769934) Streptococcus pneumoniae ATCC 700669 7329360 YP_002511701.1 CDS SPN23F_18230 NC_011900.1 1769951 1770268 R sugar phosphotransferase system (PTS),lactose/cellobiose-specific family, IIB component complement(1769951..1770268) Streptococcus pneumoniae ATCC 700669 7329361 YP_002511702.1 CDS SPN23F_18240 NC_011900.1 1770283 1771179 R hypothetical protein complement(1770283..1771179) Streptococcus pneumoniae ATCC 700669 7329362 YP_002511703.1 CDS SPN23F_18250 NC_011900.1 1771182 1772444 R sugar phosphotransferase system (PTS), IIC component complement(1771182..1772444) Streptococcus pneumoniae ATCC 700669 7329363 YP_002511704.1 CDS SPN23F_18260 NC_011900.1 1772724 1773902 D ROK-family repressor protein 1772724..1773902 Streptococcus pneumoniae ATCC 700669 7329364 YP_002511705.1 CDS SPN23F_18270 NC_011900.1 1774178 1774585 R GNAT family acetyltransferase complement(1774178..1774585) Streptococcus pneumoniae ATCC 700669 7329365 YP_002511706.1 CDS SPN23F_18280 NC_011900.1 1774655 1775314 D type IV prepilin peptidase family protein 1774655..1775314 Streptococcus pneumoniae ATCC 700669 7329366 YP_002511707.1 CDS SPN23F_18290 NC_011900.1 1775366 1776517 R DNA-binding protein complement(1775366..1776517) Streptococcus pneumoniae ATCC 700669 7329367 YP_002511708.1 CDS SPN23F_18300 NC_011900.1 1776532 1777263 R hypothetical protein complement(1776532..1777263) Streptococcus pneumoniae ATCC 700669 7329368 YP_002511709.1 CDS trpA NC_011900.1 1777565 1778341 R catalyzes the formation of indole and glyceraldehyde 3-phosphate from indoleglycerol phosphate in tryptophan biosynthesis; tryptophan synthase subunit alpha complement(1777565..1778341) Streptococcus pneumoniae ATCC 700669 7329369 YP_002511710.1 CDS trpB NC_011900.1 1778334 1779557 R catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate; tryptophan synthase subunit beta complement(1778334..1779557) Streptococcus pneumoniae ATCC 700669 7327645 YP_002511711.1 CDS trpF NC_011900.1 1779535 1780134 R catalyzes the formation of 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate from N-(5-phospho-beta-D-ribosyl)-anthranilate in tryptophan biosynthesis; N-(5'-phosphoribosyl)anthranilate isomerase complement(1779535..1780134) Streptococcus pneumoniae ATCC 700669 7327646 YP_002511712.1 CDS trpC NC_011900.1 1780121 1780888 R involved in tryptophan biosynthesis; amino acid biosynthesis; converts 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate to C(1)-(3-indolyl)-glycerol 3-phosphate and carbon dioxide and water; indole-3-glycerol-phosphate synthase complement(1780121..1780888) Streptococcus pneumoniae ATCC 700669 7327650 YP_002511713.1 CDS trpD NC_011900.1 1780885 1781889 R Catalyzes the conversion of N-(5-phospho-D-ribosyl)-anthranilate and diphosphate to anthranilate and 5-phospho-alpha-D-ribose 1-diphosphate; anthranilate phosphoribosyltransferase complement(1780885..1781889) Streptococcus pneumoniae ATCC 700669 7327647 YP_002511714.1 CDS trpG NC_011900.1 1781900 1782466 R TrpG; with TrpE catalyzes the formation of anthranilate and glutamate from chorismate and glutamine; TrpG provides the glutamine amidotransferase activity; anthranilate synthase component II complement(1781900..1782466) Streptococcus pneumoniae ATCC 700669 7327648 YP_002511715.1 CDS trpE NC_011900.1 1782463 1783824 R with component II, the glutamine amidotransferase, catalyzes the formation of anthranilate from chorismate and glutamine; anthranilate synthase component I complement(1782463..1783824) Streptococcus pneumoniae ATCC 700669 7327651 YP_002511716.1 CDS SPN23F_18390 NC_011900.1 1785009 1786010 R LacI-family transcriptional regulator (catabolite control protein) complement(1785009..1786010) Streptococcus pneumoniae ATCC 700669 7329474 YP_002511717.1 CDS SPN23F_18400 NC_011900.1 1786118 1786486 R hypothetical protein complement(1786118..1786486) Streptococcus pneumoniae ATCC 700669 7329370 YP_002511718.1 CDS SPN23F_18410 NC_011900.1 1786582 1787292 R cation transporter complement(1786582..1787292) Streptococcus pneumoniae ATCC 700669 7329371 YP_002511719.1 CDS SPN23F_18420 NC_011900.1 1787295 1788986 R inner membrane component of ABC transporter complement(1787295..1788986) Streptococcus pneumoniae ATCC 700669 7329372 YP_002511720.1 CDS SPN23F_18430 NC_011900.1 1788998 1790008 R iron ABC transporter ATP-binding protein complement(1788998..1790008) Streptococcus pneumoniae ATCC 700669 7329373 YP_002511721.1 CDS SPN23F_18440 NC_011900.1 1790112 1791179 R iron ABC transporter, solute-binding protein complement(1790112..1791179) Streptococcus pneumoniae ATCC 700669 7329374 YP_002511722.1 CDS SPN23F_18450 NC_011900.1 1791204 1791863 R hypothetical protein complement(1791204..1791863) Streptococcus pneumoniae ATCC 700669 7329375 YP_002511723.1 CDS galE NC_011900.1 1792073 1793053 R UDP-glucose 4-epimerase complement(1792073..1793053) Streptococcus pneumoniae ATCC 700669 7329376 YP_002511724.1 CDS SPN23F_18470 NC_011900.1 1793066 1794541 R catalyzes the formation of alpha-D-glucose 1-phosphate and UDP-galactose from UDP-glucose and alpha-D-galactose 1-phosphate in galactose metabolism; galactose-1-phosphate uridylyltransferase complement(1793066..1794541) Streptococcus pneumoniae ATCC 700669 7328581 YP_002511725.1 CDS SPN23F_18480 NC_011900.1 1794554 1795195 R phosphate transport system protein complement(1794554..1795195) Streptococcus pneumoniae ATCC 700669 7329377 YP_002511726.1 CDS SPN23F_18490 NC_011900.1 1795253 1795654 R hypothetical protein complement(1795253..1795654) Streptococcus pneumoniae ATCC 700669 7329378 YP_002511727.1 CDS SPN23F_18500 NC_011900.1 1795808 1796104 R hypothetical protein complement(1795808..1796104) Streptococcus pneumoniae ATCC 700669 7329379 YP_002511728.1 CDS SPN23F_18510 NC_011900.1 1796088 1798214 R sortase-sorted surface anchored protein complement(1796088..1798214) Streptococcus pneumoniae ATCC 700669 7329380 YP_002511729.1 CDS SPN23F_18530 NC_011900.1 1799378 1800604 R DegT/DnrJ/EryC1/StrS family amino sugar synthetase complement(1799378..1800604) Streptococcus pneumoniae ATCC 700669 7329381 YP_002511730.1 CDS SPN23F_18540 NC_011900.1 1800647 1801339 R sugar transferase complement(1800647..1801339) Streptococcus pneumoniae ATCC 700669 7329382 YP_002511731.1 CDS SPN23F_18550 NC_011900.1 1801512 1803263 R ABC transporter ATP-binding protein/permease complement(1801512..1803263) Streptococcus pneumoniae ATCC 700669 7329383 YP_002511732.1 CDS SPN23F_18560 NC_011900.1 1803253 1804998 R ABC transporter ATP-binding protein/permease complement(1803253..1804998) Streptococcus pneumoniae ATCC 700669 7329384 YP_002511733.1 CDS SPN23F_18570 NC_011900.1 1805126 1805581 R hypothetical protein complement(1805126..1805581) Streptococcus pneumoniae ATCC 700669 7329385 YP_002511734.1 CDS SPN23F_18580 NC_011900.1 1805653 1805832 R hypothetical protein complement(1805653..1805832) Streptococcus pneumoniae ATCC 700669 7329386 YP_002511735.1 CDS SPN23F_18590 NC_011900.1 1805882 1806109 R hypothetical protein complement(1805882..1806109) Streptococcus pneumoniae ATCC 700669 7329387 YP_002511736.1 CDS exoA NC_011900.1 1806243 1807070 D exodeoxyribonuclease 1806243..1807070 Streptococcus pneumoniae ATCC 700669 7329388 YP_002511737.1 CDS SPN23F_18610 NC_011900.1 1807225 1807464 D hypothetical protein 1807225..1807464 Streptococcus pneumoniae ATCC 700669 7329259 YP_002511738.1 CDS xpt NC_011900.1 1808342 1808923 D Catalyzes the transfer of the phosphoribosyl moiety from 5-phospho--D-ribosyl-1-pyrophosphate (PRib-PP) to the 6-oxo-guanine and -xanthine; xanthine phosphoribosyltransferase 1808342..1808923 Streptococcus pneumoniae ATCC 700669 7329475 YP_002511739.1 CDS pbuX NC_011900.1 1808923 1810185 D xanthine permease 1808923..1810185 Streptococcus pneumoniae ATCC 700669 7329448 YP_002511740.1 CDS SPN23F_18640 NC_011900.1 1810240 1811730 R restriction enzyme complement(1810240..1811730) Streptococcus pneumoniae ATCC 700669 7328457 YP_002511741.1 CDS SPN23F_18650 NC_011900.1 1811847 1813112 D DNA modification methylase 1811847..1813112 Streptococcus pneumoniae ATCC 700669 7329390 YP_002511742.1 CDS SPN23F_18660 NC_011900.1 1813158 1813562 R thioesterase superfamily protein complement(1813158..1813562) Streptococcus pneumoniae ATCC 700669 7329391 YP_002511743.1 CDS galT NC_011900.1 1813632 1815113 R catalyzes the formation of alpha-D-glucose 1-phosphate and UDP-galactose from UDP-glucose and alpha-D-galactose 1-phosphate in galactose metabolism; galactose-1-phosphate uridylyltransferase complement(1813632..1815113) Streptococcus pneumoniae ATCC 700669 7329392 YP_002511744.1 CDS galK NC_011900.1 1815132 1816310 R catalyzes the formation of alpha-D-galactose 1-phosphate from D-galactose in galactose metabolism; galactokinase complement(1815132..1816310) Streptococcus pneumoniae ATCC 700669 7328584 YP_002511745.1 CDS galR NC_011900.1 1816475 1817482 D galactose operon repressor 1816475..1817482 Streptococcus pneumoniae ATCC 700669 7328582 YP_002511746.1 CDS SPN23F_18700 NC_011900.1 1817528 1818565 R zinc-binding dehydrogenase complement(1817528..1818565) Streptococcus pneumoniae ATCC 700669 7328583 YP_002511747.1 CDS SPN23F_18710 NC_011900.1 1818566 1818919 R MerR family transcriptional regulator complement(1818566..1818919) Streptococcus pneumoniae ATCC 700669 7329393 YP_002511748.1 CDS SPN23F_18720 NC_011900.1 1819163 1820053 R cation efflux family protein complement(1819163..1820053) Streptococcus pneumoniae ATCC 700669 7329394 YP_002511749.1 CDS SPN23F_18730 NC_011900.1 1820186 1820722 D TetR family transcriptional regulator 1820186..1820722 Streptococcus pneumoniae ATCC 700669 7329395 YP_002511750.1 CDS SPN23F_18740 NC_011900.1 1820889 1821695 R nicotinamide mononucleotide transporter complement(1820889..1821695) Streptococcus pneumoniae ATCC 700669 7329396 YP_002511751.1 CDS SPN23F_18750 NC_011900.1 1822040 1823560 R glycine/betaine ABC transporter complement(1822040..1823560) Streptococcus pneumoniae ATCC 700669 7329397 YP_002511752.1 CDS SPN23F_18760 NC_011900.1 1823553 1824281 R glycine/betaine ABC transporter ATP-binding protein complement(1823553..1824281) Streptococcus pneumoniae ATCC 700669 7329398 YP_002511753.1 CDS SPN23F_18770 NC_011900.1 1824296 1825060 R hypothetical protein complement(1824296..1825060) Streptococcus pneumoniae ATCC 700669 7329399 YP_002511754.1 CDS SPN23F_18780 NC_011900.1 1825064 1825507 R MarR-family transcriptional regulator complement(1825064..1825507) Streptococcus pneumoniae ATCC 700669 7329400 YP_002511755.1 CDS SPN23F_18790 NC_011900.1 1826189 1826485 R hypothetical protein complement(1826189..1826485) Streptococcus pneumoniae ATCC 700669 7329401 YP_002511756.1 CDS pepA NC_011900.1 1826507 1827571 R glutamyl-aminopeptidase complement(1826507..1827571) Streptococcus pneumoniae ATCC 700669 7329402 YP_002511757.1 CDS SPN23F_18810 NC_011900.1 1827972 1828673 D UDP-glucose 4-epimerase 1827972..1828673 Streptococcus pneumoniae ATCC 700669 7327823 YP_002511758.1 CDS SPN23F_18820 NC_011900.1 1829096 1830055 D iron compound ABC transporter permease 1829096..1830055 Streptococcus pneumoniae ATCC 700669 7329403 YP_002511759.1 CDS SPN23F_18830 NC_011900.1 1830045 1831001 D iron compound ABC transporter permease 1830045..1831001 Streptococcus pneumoniae ATCC 700669 7329404 YP_002511760.1 CDS SPN23F_18840 NC_011900.1 1830998 1831750 D siderophore uptake ATP-binding protein 1830998..1831750 Streptococcus pneumoniae ATCC 700669 7329405 YP_002511761.1 CDS SPN23F_18850 NC_011900.1 1831846 1832811 D siderophore uptake periplasmic binding protein 1831846..1832811 Streptococcus pneumoniae ATCC 700669 7329406 YP_002511762.1 CDS SPN23F_18860 NC_011900.1 1833036 1833278 R hypothetical protein complement(1833036..1833278) Streptococcus pneumoniae ATCC 700669 7329407 YP_002511763.1 CDS rluB NC_011900.1 1833278 1834000 R ribosomal large subunit pseudouridine synthase B complement(1833278..1834000) Streptococcus pneumoniae ATCC 700669 7329408 YP_002511764.1 CDS scpB NC_011900.1 1833987 1834556 R functions during chromosome segregation; may form a condensin-like structure with SMC and ScpA; forms a homodimer; segregation and condensation protein B complement(1833987..1834556) Streptococcus pneumoniae ATCC 700669 7327458 YP_002511765.1 CDS scpA NC_011900.1 1834575 1835303 R functions during chromosome segregation; may form a condensin-like structure with SMC and ScpB; segregation and condensation protein A complement(1834575..1835303) Streptococcus pneumoniae ATCC 700669 7329133 YP_002511766.1 CDS xerD NC_011900.1 1835303 1836037 R site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs; site-specific tyrosine recombinase XerD-like protein complement(1835303..1836037) Streptococcus pneumoniae ATCC 700669 7329132 YP_002511767.1 CDS SPN23F_18910 NC_011900.1 1836034 1836495 R hypothetical protein complement(1836034..1836495) Streptococcus pneumoniae ATCC 700669 7329446 YP_002511768.1 CDS SPN23F_18920 NC_011900.1 1836492 1837013 R phosphoesterase complement(1836492..1837013) Streptococcus pneumoniae ATCC 700669 7329409 YP_002511769.1 CDS SPN23F_18930 NC_011900.1 1836989 1837960 R HAM1-like protein; Rec-dependent growth; RgdB; yggV; it is suspected that this protein functions to remove misincorporated bases such as xanthine or hypoxanthine; deoxyribonucleotide triphosphate pyrophosphatase/hypothetical protein complement(1836989..1837960) Streptococcus pneumoniae ATCC 700669 7329410 YP_002511770.1 CDS glr NC_011900.1 1837957 1838751 R converts L-glutamate to D-glutamate, a component of peptidoglycan; glutamate racemase complement(1837957..1838751) Streptococcus pneumoniae ATCC 700669 7329411 YP_002511771.1 CDS SPN23F_18950 NC_011900.1 1838958 1839206 R hypothetical protein complement(1838958..1839206) Streptococcus pneumoniae ATCC 700669 7328611 YP_002511772.1 CDS treA NC_011900.1 1839462 1841087 R trehalose-6-phosphate hydrolase complement(1839462..1841087) Streptococcus pneumoniae ATCC 700669 7329412 YP_002511773.1 CDS SPN23F_18970 NC_011900.1 1841265 1843232 R sugar phosphotransferase system (PTS), IIABC component complement(1841265..1843232) Streptococcus pneumoniae ATCC 700669 7327583 YP_002511774.1 CDS SPN23F_18980 NC_011900.1 1843417 1844127 D GntR family transcriptional regulator 1843417..1844127 Streptococcus pneumoniae ATCC 700669 7329413 YP_002511775.1 CDS SPN23F_18990 NC_011900.1 1844160 1844963 R ABC transporter ATP-binding protein complement(1844160..1844963) Streptococcus pneumoniae ATCC 700669 7329414 YP_002511776.1 CDS SPN23F_19000 NC_011900.1 1844976 1845869 R transport system permease protein complement(1844976..1845869) Streptococcus pneumoniae ATCC 700669 7329415 YP_002511777.1 CDS SPN23F_19050 NC_011900.1 1847309 1848235 R peptide ABC transporter ATP-binding protein complement(1847309..1848235) Streptococcus pneumoniae ATCC 700669 7329418 YP_002511778.1 CDS SPN23F_19060 NC_011900.1 1848246 1849313 R peptide ABC transporter ATP-binding protein complement(1848246..1849313) Streptococcus pneumoniae ATCC 700669 7329419 YP_002511779.1 CDS SPN23F_19070 NC_011900.1 1849322 1850248 R peptide ABC transporter permease complement(1849322..1850248) Streptococcus pneumoniae ATCC 700669 7328302 YP_002511780.1 CDS SPN23F_19080 NC_011900.1 1850248 1851501 R peptide ABC transporter permease complement(1850248..1851501) Streptococcus pneumoniae ATCC 700669 7328304 YP_002511781.1 CDS SPN23F_19090 NC_011900.1 1851517 1851744 R peptide ABC transporter permease complement(1851517..1851744) Streptococcus pneumoniae ATCC 700669 7328305 YP_002511782.1 CDS SPN23F_19100 NC_011900.1 1851811 1853790 R extracellular oligopeptide-binding protein complement(1851811..1853790) Streptococcus pneumoniae ATCC 700669 7328306 YP_002511783.1 CDS SPN23F_19110 NC_011900.1 1854476 1855669 R polysaccharide repeat unit polymerase complement(1854476..1855669) Streptococcus pneumoniae ATCC 700669 7328307 YP_002511784.1 CDS SPN23F_19120 NC_011900.1 1855807 1857249 R sucrose phosphorylase complement(1855807..1857249) Streptococcus pneumoniae ATCC 700669 7328308 YP_002511785.1 CDS msmG NC_011900.1 1857607 1858440 R multiple sugar-binding transport system permease protein complement(1857607..1858440) Streptococcus pneumoniae ATCC 700669 7328309 YP_002511786.1 CDS msmF NC_011900.1 1858454 1859320 R multiple sugar-binding transport system permease protein complement(1858454..1859320) Streptococcus pneumoniae ATCC 700669 7328137 YP_002511787.1 CDS msmE NC_011900.1 1859334 1860593 R multiple sugar-binding protein precursor complement(1859334..1860593) Streptococcus pneumoniae ATCC 700669 7328136 YP_002511788.1 CDS aga NC_011900.1 1860685 1862847 R alpha-galactosidase complement(1860685..1862847) Streptococcus pneumoniae ATCC 700669 7328135 YP_002511789.1 CDS msmR NC_011900.1 1862955 1863815 D AraC family transcriptional regulator 1862955..1863815 Streptococcus pneumoniae ATCC 700669 7328639 YP_002511790.1 CDS birA NC_011900.1 1863812 1864747 D catalyzes the formation of biotinyl-5'-AMP, also acts as a transcriptional repressor of the biotin operon; biotin--protein ligase 1863812..1864747 Streptococcus pneumoniae ATCC 700669 7328139 YP_002511791.1 CDS SPN23F_19230 NC_011900.1 1873080 1874423 R RNA methyltransferase complement(1873080..1874423) Streptococcus pneumoniae ATCC 700669 7327604 YP_002511792.1 CDS recX NC_011900.1 1874473 1875249 D binds RecA and inhibits RecA-mediated DNA strand exchange and ATP hydrolysis and coprotease activities; recombination regulator RecX 1874473..1875249 Streptococcus pneumoniae ATCC 700669 7328311 YP_002511793.1 CDS SPN23F_19250 NC_011900.1 1875338 1875871 D hypothetical protein 1875338..1875871 Streptococcus pneumoniae ATCC 700669 7328312 YP_002511794.1 CDS groEL NC_011900.1 1878020 1879642 R 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth; chaperonin GroEL complement(1878020..1879642) Streptococcus pneumoniae ATCC 700669 7328315 YP_002511795.1 CDS groES NC_011900.1 1879658 1879942 R 10 kDa chaperonin; Cpn10; GroES; forms homoheptameric ring; binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it; folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES; release of the folded substrate is dependent on ATP binding and hydrolysis in the trans ring; co-chaperonin GroES complement(1879658..1879942) Streptococcus pneumoniae ATCC 700669 7328622 YP_002511796.1 CDS SPN23F_19320 NC_011900.1 1880098 1880493 R binds to single stranded DNA and may facilitate the binding and interaction of other proteins to DNA; single-stranded DNA-binding protein complement(1880098..1880493) Streptococcus pneumoniae ATCC 700669 7328061 YP_002511797.1 CDS SPN23F_19330 NC_011900.1 1880571 1881332 R NADP-dependent L-serine/L-allo-threonine dehydrogenase complement(1880571..1881332) Streptococcus pneumoniae ATCC 700669 7328316 YP_002511798.1 CDS SPN23F_19340 NC_011900.1 1881374 1882000 R tRNA-binding protein complement(1881374..1882000) Streptococcus pneumoniae ATCC 700669 7328317 YP_002511799.1 CDS SPN23F_19350 NC_011900.1 1882016 1882333 R thioredoxin complement(1882016..1882333) Streptococcus pneumoniae ATCC 700669 7328318 YP_002511800.1 CDS SPN23F_19360 NC_011900.1 1882330 1882620 R hypothetical protein complement(1882330..1882620) Streptococcus pneumoniae ATCC 700669 7328319 YP_002511801.1 CDS SPN23F_19370 NC_011900.1 1882914 1883015 R may be a gene fragment; cell wall-binding protein complement(1882914..1883015) Streptococcus pneumoniae ATCC 700669 7328320 YP_002511802.1 CDS SPN23F_19380 NC_011900.1 1883266 1883940 R hypothetical protein complement(1883266..1883940) Streptococcus pneumoniae ATCC 700669 7328321 YP_002511803.1 CDS SPN23F_19390 NC_011900.1 1883946 1884392 R DNA-binding protein complement(1883946..1884392) Streptococcus pneumoniae ATCC 700669 7328322 YP_002511804.1 CDS SPN23F_19400 NC_011900.1 1884506 1885009 R PAP2 superfamily membrane protein complement(1884506..1885009) Streptococcus pneumoniae ATCC 700669 7328323 YP_002511805.1 CDS SPN23F_19410 NC_011900.1 1885006 1885368 R hypothetical protein complement(1885006..1885368) Streptococcus pneumoniae ATCC 700669 7328324 YP_002511806.1 CDS SPN23F_19440 NC_011900.1 1886472 1887293 R ABC transporter ATP-binding protein/permease complement(1886472..1887293) Streptococcus pneumoniae ATCC 700669 7328327 YP_002511807.1 CDS SPN23F_19450 NC_011900.1 1887331 1887780 R MarR family transcriptional regulator complement(1887331..1887780) Streptococcus pneumoniae ATCC 700669 7328328 YP_002511808.1 CDS SPN23F_19460 NC_011900.1 1887904 1888620 R hypothetical protein complement(1887904..1888620) Streptococcus pneumoniae ATCC 700669 7328329 YP_002511809.1 CDS ply NC_011900.1 1889503 1890918 R pneumolysin (thiol-activated cytolysin) complement(1889503..1890918) Streptococcus pneumoniae ATCC 700669 7328330 YP_002511810.1 CDS SPN23F_19480 NC_011900.1 1890929 1891261 R hypothetical protein complement(1890929..1891261) Streptococcus pneumoniae ATCC 700669 7327853 YP_002511811.1 CDS SPN23F_19490 NC_011900.1 1891332 1891940 R hypothetical protein complement(1891332..1891940) Streptococcus pneumoniae ATCC 700669 7328331 YP_002511812.1 CDS SPN23F_19500 NC_011900.1 1891953 1892411 R hypothetical protein complement(1891953..1892411) Streptococcus pneumoniae ATCC 700669 7328332 YP_002511813.1 CDS SPN23F_19530 NC_011900.1 1894103 1894363 R hypothetical protein complement(1894103..1894363) Streptococcus pneumoniae ATCC 700669 7328335 YP_002511814.1 CDS SPN23F_19540 NC_011900.1 1894422 1894973 R hypothetical protein complement(1894422..1894973) Streptococcus pneumoniae ATCC 700669 7328336 YP_002511815.1 CDS SPN23F_19550 NC_011900.1 1894963 1895160 R hypothetical protein complement(1894963..1895160) Streptococcus pneumoniae ATCC 700669 7328337 YP_002511816.1 CDS SPN23F_19560 NC_011900.1 1895164 1895958 R hypothetical protein complement(1895164..1895958) Streptococcus pneumoniae ATCC 700669 7328338 YP_002511817.1 CDS SPN23F_19570 NC_011900.1 1896366 1896791 R hypothetical protein complement(1896366..1896791) Streptococcus pneumoniae ATCC 700669 7328339 YP_002511818.1 CDS SPN23F_19580 NC_011900.1 1896920 1897279 R hypothetical protein complement(1896920..1897279) Streptococcus pneumoniae ATCC 700669 7328340 YP_002511819.1 CDS SPN23F_19590 NC_011900.1 1897518 1897679 R DNA-binding protein complement(1897518..1897679) Streptococcus pneumoniae ATCC 700669 7328341 YP_002511820.1 CDS SPN23F_19600 NC_011900.1 1898038 1898994 R No appparent secretion signal; cell wall-binding amidase complement(1898038..1898994) Streptococcus pneumoniae ATCC 700669 7328342 YP_002511821.1 CDS SPN23F_19610 NC_011900.1 1899370 1900740 R drug/sodium antiporter complement(1899370..1900740) Streptococcus pneumoniae ATCC 700669 7328343 YP_002511822.1 CDS recA NC_011900.1 1901047 1902213 R catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs; recombinase A complement(1901047..1902213) Streptococcus pneumoniae ATCC 700669 7328344 YP_002511823.1 CDS cinA NC_011900.1 1902268 1903524 R competence damage-inducible protein A complement(1902268..1903524) Streptococcus pneumoniae ATCC 700669 7327442 YP_002511824.1 CDS SPN23F_19640 NC_011900.1 1903609 1904625 R LytR family transcriptional regulator complement(1903609..1904625) Streptococcus pneumoniae ATCC 700669 7329194 YP_002511825.1 CDS SPN23F_19650 NC_011900.1 1904633 1905151 R GNAT family acetyltransferase complement(1904633..1905151) Streptococcus pneumoniae ATCC 700669 7328345 YP_002511826.1 CDS SPN23F_19660 NC_011900.1 1905141 1905584 R P-loop hydrolase complement(1905141..1905584) Streptococcus pneumoniae ATCC 700669 7328346 YP_002511827.1 CDS SPN23F_19670 NC_011900.1 1905670 1906290 R hypothetical protein complement(1905670..1906290) Streptococcus pneumoniae ATCC 700669 7328347 YP_002511828.1 CDS SPN23F_19680 NC_011900.1 1906673 1907536 R transcriptional regulator complement(1906673..1907536) Streptococcus pneumoniae ATCC 700669 7328348 YP_002511829.1 CDS SPN23F_19690 NC_011900.1 1907728 1907898 D secreted protein 1907728..1907898 Streptococcus pneumoniae ATCC 700669 7328349 YP_002511830.1 CDS SPN23F_19700 NC_011900.1 1908001 1908225 D hypothetical protein 1908001..1908225 Streptococcus pneumoniae ATCC 700669 7328350 YP_002511831.1 CDS SPN23F_19710 NC_011900.1 1908232 1908420 D hypothetical protein 1908232..1908420 Streptococcus pneumoniae ATCC 700669 7328351 YP_002511832.1 CDS SPN23F_19720 NC_011900.1 1908536 1911526 D lantibiotic modifying enzyme 1908536..1911526 Streptococcus pneumoniae ATCC 700669 7328352 YP_002511833.1 CDS SPN23F_19730 NC_011900.1 1911876 1912580 D hypothetical protein 1911876..1912580 Streptococcus pneumoniae ATCC 700669 7328353 YP_002511834.1 CDS SPN23F_19740 NC_011900.1 1912561 1913490 D hypothetical protein 1912561..1913490 Streptococcus pneumoniae ATCC 700669 7328354 YP_002511835.1 CDS SPN23F_19750 NC_011900.1 1913487 1915595 D bacteriocin secretion/processing ATP-binding protein 1913487..1915595 Streptococcus pneumoniae ATCC 700669 7328355 YP_002511836.1 CDS SPN23F_19760 NC_011900.1 1915619 1917358 D lantibiotic leader peptide processing serine protease 1915619..1917358 Streptococcus pneumoniae ATCC 700669 7328356 YP_002511837.1 CDS SPN23F_19780 NC_011900.1 1918178 1918810 D ABC transporter ATP-binding protein 1918178..1918810 Streptococcus pneumoniae ATCC 700669 7328358 YP_002511838.1 CDS SPN23F_19790 NC_011900.1 1918968 1919129 D hypothetical protein 1918968..1919129 Streptococcus pneumoniae ATCC 700669 7328359 YP_002511839.1 CDS ndk NC_011900.1 1919755 1920168 R catalyzes the formation of nucleoside triphosphate from ATP and nucleoside diphosphate; nucleoside diphosphate kinase complement(1919755..1920168) Streptococcus pneumoniae ATCC 700669 7328360 YP_002511840.1 CDS rpoC NC_011900.1 1920279 1923956 R DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Subunit beta' binds to sigma factor allowing it to bind to the -10 region of the promoter; DNA-directed RNA polymerase subunit beta' complement(1920279..1923956) Streptococcus pneumoniae ATCC 700669 7328419 YP_002511841.1 CDS rpoB NC_011900.1 1923989 1927600 R DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme; DNA-directed RNA polymerase subunit beta complement(1923989..1927600) Streptococcus pneumoniae ATCC 700669 7329105 YP_002511842.1 CDS SPN23F_19830 NC_011900.1 1928284 1929615 R transport protein complement(1928284..1929615) Streptococcus pneumoniae ATCC 700669 7327600 YP_002511843.1 CDS endA NC_011900.1 1929844 1930668 R competence associated endonuclease complement(1929844..1930668) Streptococcus pneumoniae ATCC 700669 7328361 YP_002511844.1 CDS epuA NC_011900.1 1930707 1930895 R competence associated protein complement(1930707..1930895) Streptococcus pneumoniae ATCC 700669 7329252 YP_002511845.1 CDS murA1 NC_011900.1 1930888 1932171 R adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active; UDP-N-acetylglucosamine 1-carboxyvinyltransferase complement(1930888..1932171) Streptococcus pneumoniae ATCC 700669 7329257 YP_002511846.1 CDS SPN23F_19870 NC_011900.1 1932195 1932425 R hypothetical protein complement(1932195..1932425) Streptococcus pneumoniae ATCC 700669 7328391 YP_002511847.1 CDS SPN23F_19880 NC_011900.1 1932483 1933520 R hypothetical protein complement(1932483..1933520) Streptococcus pneumoniae ATCC 700669 7328362 YP_002511848.1 CDS coaD NC_011900.1 1933504 1933992 R Catalyzes the conversion of ATP and pantetheine 4'-phosphate to diphosphate and 3'-dephospho-coA; phosphopantetheine adenylyltransferase complement(1933504..1933992) Streptococcus pneumoniae ATCC 700669 7328363 YP_002511849.1 CDS SPN23F_19900 NC_011900.1 1933982 1934521 R methylase complement(1933982..1934521) Streptococcus pneumoniae ATCC 700669 7329203 YP_002511850.1 CDS asnA NC_011900.1 1934586 1935578 R catalyzes the formation of asparagine from aspartate and ammonia; asparagine synthetase AsnA complement(1934586..1935578) Streptococcus pneumoniae ATCC 700669 7328364 YP_002511851.1 CDS SPN23F_19930 NC_011900.1 1935690 1936373 R hypothetical protein complement(1935690..1936373) Streptococcus pneumoniae ATCC 700669 7328667 YP_002511852.1 CDS SPN23F_19940 NC_011900.1 1936429 1937169 R SpoU rRNA Methylase family protein complement(1936429..1937169) Streptococcus pneumoniae ATCC 700669 7328365 YP_002511853.1 CDS SPN23F_19950 NC_011900.1 1937203 1937481 D catalyzes the hydrolysis of acylphosphate; acylphosphatase 1937203..1937481 Streptococcus pneumoniae ATCC 700669 7328366 YP_002511854.1 CDS SPN23F_19960 NC_011900.1 1937559 1938485 D involved in biogenesis of membrane proteins; Firmicutes specific proteins are shorter than other bacterial counterparts and have a signal peptide and lipid attachment site; OxaA-like protein precursor 1937559..1938485 Streptococcus pneumoniae ATCC 700669 7328367 YP_002511855.1 CDS pflC NC_011900.1 1938560 1939354 R pyruvate formate-lyase activating enzyme complement(1938560..1939354) Streptococcus pneumoniae ATCC 700669 7328368 YP_002511856.1 CDS SPN23F_19980 NC_011900.1 1939480 1940730 R pyridoxal-dependent decarboxylase complement(1939480..1940730) Streptococcus pneumoniae ATCC 700669 7327835 YP_002511857.1 CDS purR NC_011900.1 1940797 1941624 R pur operon repressor complement(1940797..1941624) Streptococcus pneumoniae ATCC 700669 7328369 YP_002511858.1 CDS SPN23F_20000 NC_011900.1 1941891 1942832 R 3'-5' exoribonuclease complement(1941891..1942832) Streptococcus pneumoniae ATCC 700669 7327426 YP_002511859.1 CDS SPN23F_20010 NC_011900.1 1942822 1944078 R RmuC family protein complement(1942822..1944078) Streptococcus pneumoniae ATCC 700669 7328370 YP_002511860.1 CDS thiN NC_011900.1 1944080 1944742 R thiamin pyrophosphokinase complement(1944080..1944742) Streptococcus pneumoniae ATCC 700669 7328371 YP_002511861.1 CDS rpe NC_011900.1 1944705 1945361 R ribulose-phosphate 3-epimerase complement(1944705..1945361) Streptococcus pneumoniae ATCC 700669 7329172 YP_002511862.1 CDS engC NC_011900.1 1945372 1946250 R EngC; RsgA; CpgA; circularly permuted GTPase; ribosome small subunit-dependent GTPase A; has the pattern G4-G1-G3 as opposed to other GTPases; interacts strongly with 30S ribosome which stimulates GTPase activity; ribosome-associated GTPase complement(1945372..1946250) Streptococcus pneumoniae ATCC 700669 7327468 YP_002511863.1 CDS ksgA NC_011900.1 1946252 1947124 R catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin; dimethyladenosine transferase complement(1946252..1947124) Streptococcus pneumoniae ATCC 700669 7329255 YP_002511864.1 CDS SPN23F_20060 NC_011900.1 1947255 1947563 R hypothetical protein complement(1947255..1947563) Streptococcus pneumoniae ATCC 700669 7328090 YP_002511865.1 CDS SPN23F_20070 NC_011900.1 1947556 1948197 R ABC transporter ATP-binding protein complement(1947556..1948197) Streptococcus pneumoniae ATCC 700669 7328372 YP_002511866.1 CDS SPN23F_20080 NC_011900.1 1948199 1950229 R hypothetical protein complement(1948199..1950229) Streptococcus pneumoniae ATCC 700669 7328373 YP_002511867.1 CDS SPN23F_20090 NC_011900.1 1950306 1950602 R hypothetical protein complement(1950306..1950602) Streptococcus pneumoniae ATCC 700669 7328374 YP_002511868.1 CDS SPN23F_20100 NC_011900.1 1950922 1951821 R DNA-binding protein complement(1950922..1951821) Streptococcus pneumoniae ATCC 700669 7328375 YP_002511869.1 CDS SPN23F_20110 NC_011900.1 1951893 1952453 R hypothetical protein complement(1951893..1952453) Streptococcus pneumoniae ATCC 700669 7328376 YP_002511870.1 CDS SPN23F_20120 NC_011900.1 1952453 1953226 R TatD related DNase complement(1952453..1953226) Streptococcus pneumoniae ATCC 700669 7328377 YP_002511871.1 CDS rpmH NC_011900.1 1954708 1954842 R in Escherichia coli transcription of this gene is enhanced by polyamines; 50S ribosomal protein L34 complement(1954708..1954842) Streptococcus pneumoniae ATCC 700669 7328379 YP_002511872.1 CDS SPN23F_20150 NC_011900.1 1954987 1956201 R broad specificity; family IV; in Corynebacterium glutamicum this protein can use glutamate, 2-aminobutyrate, and aspartate as amino donors and pyruvate as the acceptor; aminotransferase AlaT complement(1954987..1956201) Streptococcus pneumoniae ATCC 700669 7329101 YP_002511873.1 CDS SPN23F_20160 NC_011900.1 1956357 1956650 R hypothetical protein complement(1956357..1956650) Streptococcus pneumoniae ATCC 700669 7328380 YP_002511874.1 CDS SPN23F_20170 NC_011900.1 1956812 1957264 D universal stress protein 1956812..1957264 Streptococcus pneumoniae ATCC 700669 7328381 YP_002511875.1 CDS SPN23F_20180 NC_011900.1 1957299 1958687 R haloacid dehalogenase-like hydrolase complement(1957299..1958687) Streptococcus pneumoniae ATCC 700669 7328382 YP_002511876.1 CDS asnB NC_011900.1 1958753 1959715 D L-asparaginase 1958753..1959715 Streptococcus pneumoniae ATCC 700669 7327900 YP_002511877.1 CDS ccpA NC_011900.1 1959921 1960931 R catabolite control protein A complement(1959921..1960931) Streptococcus pneumoniae ATCC 700669 7328668 YP_002511878.1 CDS SPN23F_20210 NC_011900.1 1961356 1961955 R response regulator protein complement(1961356..1961955) Streptococcus pneumoniae ATCC 700669 7329189 YP_002511879.1 CDS SPN23F_20220 NC_011900.1 1961957 1963054 R histidine sensor kinase protein complement(1961957..1963054) Streptococcus pneumoniae ATCC 700669 7327980 YP_002511880.1 CDS SPN23F_20230 NC_011900.1 1963054 1963791 R ABC transporter complement(1963054..1963791) Streptococcus pneumoniae ATCC 700669 7327981 YP_002511881.1 CDS SPN23F_20240 NC_011900.1 1963793 1964677 R ABC transporter ATP-binding protein complement(1963793..1964677) Streptococcus pneumoniae ATCC 700669 7327982 YP_002511882.1 CDS SPN23F_20250 NC_011900.1 1964664 1964858 R hypothetical protein complement(1964664..1964858) Streptococcus pneumoniae ATCC 700669 7327983 YP_002511883.1 CDS comX NC_011900.1 1971741 1972220 R competence-specific global transcription modulator complement(1971741..1972220) Streptococcus pneumoniae ATCC 700669 7327605 YP_002511884.1 CDS nusG NC_011900.1 1972342 1972878 R Modulates Rho-dependent transcription termination; transcription antitermination protein NusG complement(1972342..1972878) Streptococcus pneumoniae ATCC 700669 7329212 YP_002511885.1 CDS secE NC_011900.1 1972933 1973109 R forms a complex with SecY and SecG; SecYEG forms a protein-conducting channel to which secA binds and translocates targeted polypeptides across the cytoplasmic membrane, a process driven by ATP and a proton-motive force; preprotein translocase subunit SecE complement(1972933..1973109) Streptococcus pneumoniae ATCC 700669 7328435 YP_002511886.1 CDS pbp2A NC_011900.1 1973324 1975519 R penicillin-binding protein 2a complement(1973324..1975519) Streptococcus pneumoniae ATCC 700669 7327986 YP_002511887.1 CDS SPN23F_20320 NC_011900.1 1975645 1976481 D RNA pseudouridylate synthase 1975645..1976481 Streptococcus pneumoniae ATCC 700669 7328455 YP_002511888.1 CDS plr NC_011900.1 1976549 1977556 R glyceraldehyde-3-phosphate dehydrogenase, plasmin receptor complement(1976549..1977556) Streptococcus pneumoniae ATCC 700669 7327987 YP_002511889.1 CDS SPN23F_20340 NC_011900.1 1977733 1978566 R puttaive FtsX-family transport protein complement(1977733..1978566) Streptococcus pneumoniae ATCC 700669 7327851 YP_002511890.1 CDS nadC NC_011900.1 1979746 1980618 R catalyzes the formation of pyridine-2,3-dicarboxylate and 5-phospho-alpha-D-ribose 1-diphosphate from nictinate D-ribonucleotide; nicotinate-nucleotide pyrophosphorylase complement(1979746..1980618) Streptococcus pneumoniae ATCC 700669 7327990 YP_002511891.1 CDS SPN23F_20380 NC_011900.1 1980855 1982165 D dicarboxylate carrier protein 1980855..1982165 Streptococcus pneumoniae ATCC 700669 7328411 YP_002511892.1 CDS SPN23F_20400 NC_011900.1 1982531 1982662 R nucleotide-binding protein complement(1982531..1982662) Streptococcus pneumoniae ATCC 700669 7327992 YP_002511893.1 CDS treR NC_011900.1 1983185 1983913 R GntR family transcriptional regulator complement(1983185..1983913) Streptococcus pneumoniae ATCC 700669 7327993 YP_002511894.1 CDS SPN23F_20420 NC_011900.1 1984071 1985480 D beta-glucosidase 1984071..1985480 Streptococcus pneumoniae ATCC 700669 7327584 YP_002511895.1 CDS licC NC_011900.1 1985498 1986793 D PTS system, lichenan-specific IIc component 1985498..1986793 Streptococcus pneumoniae ATCC 700669 7327994 YP_002511896.1 CDS SPN23F_20440 NC_011900.1 1986798 1987106 D exported PTS system protein 1986798..1987106 Streptococcus pneumoniae ATCC 700669 7328108 YP_002511897.1 CDS SPN23F_20450 NC_011900.1 1987103 1987411 D lactose-specific phosphotransferase system (PTS), IIA component 2 1987103..1987411 Streptococcus pneumoniae ATCC 700669 7327995 YP_002511898.1 CDS adhE NC_011900.1 1988278 1990929 R bifunctional acetaldehyde-CoA/alcohol dehydrogenase complement(1988278..1990929) Streptococcus pneumoniae ATCC 700669 7327996 YP_002511899.1 CDS SPN23F_20480 NC_011900.1 1991229 1991639 R hypothetical protein complement(1991229..1991639) Streptococcus pneumoniae ATCC 700669 7328636 YP_002511900.1 CDS SPN23F_20490 NC_011900.1 1991641 1992069 R phosphotyrosine protein phosphatase complement(1991641..1992069) Streptococcus pneumoniae ATCC 700669 7327997 YP_002511901.1 CDS yajC NC_011900.1 1992116 1992415 R member of preprotein translocase; forms a heterotrimer with SecD and SecF; links the SecD/SecF/YajC/YidC complex with the SecY/SecE/SecG complex; preprotein translocase subunit YajC complement(1992116..1992415) Streptococcus pneumoniae ATCC 700669 7327998 YP_002511902.1 CDS tkt NC_011900.1 1992532 1994508 R catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase; transketolase complement(1992532..1994508) Streptococcus pneumoniae ATCC 700669 7327999 YP_002511903.1 CDS SPN23F_20520 NC_011900.1 1994622 1995713 R L-ascorbate 6-phosphate lactonase complement(1994622..1995713) Streptococcus pneumoniae ATCC 700669 7329177 YP_002511904.1 CDS SPN23F_20530 NC_011900.1 1995825 1997498 R transcriptional antiterminator complement(1995825..1997498) Streptococcus pneumoniae ATCC 700669 7328000 YP_002511905.1 CDS araD NC_011900.1 1997677 1998381 R catalyzes the formation of D-xylulose 5-phosphate from L-ribulose 5-phosphate in the L-arabinose and L-ascorbate degradation pathways; L-ribulose-5-phosphate 4-epimerase complement(1997677..1998381) Streptococcus pneumoniae ATCC 700669 7328001 YP_002511906.1 CDS ulaD NC_011900.1 1999245 1999910 R catalyzes the formation of L-xylulose-5-phosphate from 3-keto-L-gulonate-6-phosphate in anaerobic L-ascorbate utilization; 3-keto-L-gulonate-6-phosphate decarboxylase complement(1999245..1999910) Streptococcus pneumoniae ATCC 700669 7328004 YP_002511907.1 CDS SPN23F_20580 NC_011900.1 1999927 2000412 R sugar phosphotransferase system (PTS), IIA component complement(1999927..2000412) Streptococcus pneumoniae ATCC 700669 7328005 YP_002511908.1 CDS SPN23F_20590 NC_011900.1 2000489 2000770 R sugar phosphotransferase system (PTS),lactose/cellobiose-specific family, IIB subunit protein complement(2000489..2000770) Streptococcus pneumoniae ATCC 700669 7328006 YP_002511909.1 CDS SPN23F_20600 NC_011900.1 2000793 2002250 R membrane component; functions with enzymes IIB (sgaB; ulaB) and IIA (sgaA; ulaC) enzyme I and HPr for anaerobic utilization and uptake of L-ascorbate; sgaTBA are regulated by yifQ as well as Crp and Fnr; PTS system ascorbate-specific transporter subunit IIC complement(2000793..2002250) Streptococcus pneumoniae ATCC 700669 7328007 YP_002511910.1 CDS SPN23F_20610 NC_011900.1 2002381 2003004 R hypothetical protein complement(2002381..2003004) Streptococcus pneumoniae ATCC 700669 7328008 YP_002511911.1 CDS SPN23F_20620 NC_011900.1 2003055 2004041 R ssDNA-binding protein complement(2003055..2004041) Streptococcus pneumoniae ATCC 700669 7328009 YP_002511912.1 CDS SPN23F_20630 NC_011900.1 2004060 2004890 R membrane protein OxaA 1 precursor complement(2004060..2004890) Streptococcus pneumoniae ATCC 700669 7328010 YP_002511913.1 CDS rnpA NC_011900.1 2004859 2005230 R protein component of RNaseP which catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'terminus; this enzyme also cleaves other RNA substrates; ribonuclease P complement(2004859..2005230) Streptococcus pneumoniae ATCC 700669 7328011 YP_002511914.1 CDS ackA NC_011900.1 2005379 2006569 R AckA utilizes acetate and can acetylate CheY which increases signal strength during flagellar rotation; utilizes magnesium and ATP; also involved in conversion of acetate to aceyl-CoA; acetate kinase complement(2005379..2006569) Streptococcus pneumoniae ATCC 700669 7327465 YP_002511915.1 CDS SPN23F_20670 NC_011900.1 2006620 2007573 R hypothetical protein complement(2006620..2007573) Streptococcus pneumoniae ATCC 700669 7328628 YP_002511916.1 CDS SPN23F_20700 NC_011900.1 2008331 2008777 R hypothetical protein complement(2008331..2008777) Streptococcus pneumoniae ATCC 700669 7328013 YP_002511917.1 CDS SPN23F_20710 NC_011900.1 2008755 2009216 R hypothetical protein complement(2008755..2009216) Streptococcus pneumoniae ATCC 700669 7328014 YP_002511918.1 CDS SPN23F_20720 NC_011900.1 2009179 2009439 R hypothetical protein complement(2009179..2009439) Streptococcus pneumoniae ATCC 700669 7328015 YP_002511919.1 CDS SPN23F_20730 NC_011900.1 2009444 2009848 R competence protein complement(2009444..2009848) Streptococcus pneumoniae ATCC 700669 7328016 YP_002511920.1 CDS comYC NC_011900.1 2009841 2010167 R competence protein complement(2009841..2010167) Streptococcus pneumoniae ATCC 700669 7328017 YP_002511921.1 CDS SPN23F_20750 NC_011900.1 2010169 2011017 R competence protein complement(2010169..2011017) Streptococcus pneumoniae ATCC 700669 7329213 YP_002511922.1 CDS SPN23F_20760 NC_011900.1 2011133 2012074 R competence protein complement(2011133..2012074) Streptococcus pneumoniae ATCC 700669 7328018 YP_002511923.1 CDS SPN23F_20770 NC_011900.1 2012150 2012515 R hypothetical protein complement(2012150..2012515) Streptococcus pneumoniae ATCC 700669 7328019 YP_002511924.1 CDS SPN23F_20780 NC_011900.1 2012666 2013724 R zinc-binding alcohol dehydrogenase complement(2012666..2013724) Streptococcus pneumoniae ATCC 700669 7328020 YP_002511925.1 CDS SPN23F_20790 NC_011900.1 2013887 2015038 R N-acetylglucosamine-6-phosphate deacetylase complement(2013887..2015038) Streptococcus pneumoniae ATCC 700669 7328021 YP_002511926.1 CDS SPN23F_20800 NC_011900.1 2015191 2017008 R acyltransferase family protein complement(2015191..2017008) Streptococcus pneumoniae ATCC 700669 7328022 YP_002511927.1 CDS tgt NC_011900.1 2017109 2018251 R Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr); queuine tRNA-ribosyltransferase complement(2017109..2018251) Streptococcus pneumoniae ATCC 700669 7328023 YP_002511928.1 CDS SPN23F_20820 NC_011900.1 2018381 2019238 D hypothetical protein 2018381..2019238 Streptococcus pneumoniae ATCC 700669 7329165 YP_002511929.1 CDS SPN23F_20830 NC_011900.1 2019266 2019910 R catalyzes the removal of 5-oxoproline from various penultimate amino acid residues except L-proline; pyrrolidone-carboxylate peptidase complement(2019266..2019910) Streptococcus pneumoniae ATCC 700669 7328024 YP_002511930.1 CDS SPN23F_20840 NC_011900.1 2020017 2020376 R hypothetical protein complement(2020017..2020376) Streptococcus pneumoniae ATCC 700669 7328025 YP_002511931.1 CDS SPN23F_20850 NC_011900.1 2020387 2020812 R MarR family transcriptional regulator complement(2020387..2020812) Streptococcus pneumoniae ATCC 700669 7328026 YP_002511932.1 CDS SPN23F_20870 NC_011900.1 2021132 2022244 R hypothetical protein complement(2021132..2022244) Streptococcus pneumoniae ATCC 700669 7328027 YP_002511933.1 CDS SPN23F_20880 NC_011900.1 2022410 2023030 R haloacid dehalogenase-like hydrolase complement(2022410..2023030) Streptococcus pneumoniae ATCC 700669 7328028 YP_002511934.1 CDS SPN23F_20890 NC_011900.1 2023034 2024314 R multi antimicrobial extrusion (MATE) family transporter complement(2023034..2024314) Streptococcus pneumoniae ATCC 700669 7328029 YP_002511935.1 CDS SPN23F_20900 NC_011900.1 2024375 2025859 R catalyzes the formation of L-threonine from O-phospho-L-homoserine; threonine synthase complement(2024375..2025859) Streptococcus pneumoniae ATCC 700669 7328030 YP_002511936.1 CDS SPN23F_20910 NC_011900.1 2025935 2027212 R hypothetical protein complement(2025935..2027212) Streptococcus pneumoniae ATCC 700669 7328031 YP_002511937.1 CDS gltX NC_011900.1 2034124 2035584 R Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation; glutamyl-tRNA synthetase complement(2034124..2035584) Streptococcus pneumoniae ATCC 700669 7327606 YP_002511938.1 CDS pgi NC_011900.1 2035708 2037057 R functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis; catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate; member of PGI family; glucose-6-phosphate isomerase complement(2035708..2037057) Streptococcus pneumoniae ATCC 700669 7328612 YP_002511939.1 CDS SPN23F_20970 NC_011900.1 2037227 2037916 R peptidase complement(2037227..2037916) Streptococcus pneumoniae ATCC 700669 7327837 YP_002511940.1 CDS SPN23F_20980 NC_011900.1 2038055 2039821 R ABC transporter ATP-binding protein complement(2038055..2039821) Streptococcus pneumoniae ATCC 700669 7328033 YP_002511941.1 CDS SPN23F_21000 NC_011900.1 2040612 2042306 R ABC transporter ATP-binding protein complement(2040612..2042306) Streptococcus pneumoniae ATCC 700669 7328035 YP_002511942.1 CDS mutS NC_011900.1 2042453 2044987 R This protein performs the mismatch recognition step during the DNA repair process; DNA mismatch repair protein MutS complement(2042453..2044987) Streptococcus pneumoniae ATCC 700669 7328036 YP_002511943.1 CDS argR NC_011900.1 2045038 2045484 R arginine repressor complement(2045038..2045484) Streptococcus pneumoniae ATCC 700669 7328402 YP_002511944.1 CDS argS NC_011900.1 2045620 2047311 D catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase; arginyl-tRNA synthetase 2045620..2047311 Streptococcus pneumoniae ATCC 700669 7328656 YP_002511945.1 CDS SPN23F_21060 NC_011900.1 2048160 2048636 D hypothetical protein 2048160..2048636 Streptococcus pneumoniae ATCC 700669 7328037 YP_002511946.1 CDS phoP NC_011900.1 2048720 2049427 D alkaline phosphatase synthesis transcriptional regulatory protein 2048720..2049427 Streptococcus pneumoniae ATCC 700669 7328038 YP_002511947.1 CDS phoR NC_011900.1 2049428 2050759 D alkaline phosphatase synthesis sensor protein 2049428..2050759 Streptococcus pneumoniae ATCC 700669 7327844 YP_002511948.1 CDS SPN23F_21090 NC_011900.1 2050926 2051801 D lipoprotein 2050926..2051801 Streptococcus pneumoniae ATCC 700669 7327845 YP_002511949.1 CDS SPN23F_21100 NC_011900.1 2051919 2052782 D ABC transporter permease 2051919..2052782 Streptococcus pneumoniae ATCC 700669 7328039 YP_002511950.1 CDS SPN23F_21110 NC_011900.1 2052775 2053590 D ABC transporter permease 2052775..2053590 Streptococcus pneumoniae ATCC 700669 7328040 YP_002511951.1 CDS pstB3 NC_011900.1 2053592 2054344 D ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation; phosphate transporter ATP-binding protein 2053592..2054344 Streptococcus pneumoniae ATCC 700669 7328041 YP_002511952.1 CDS SPN23F_21130 NC_011900.1 2054359 2055009 D phosphate transport system protein 2054359..2055009 Streptococcus pneumoniae ATCC 700669 7327887 YP_002511953.1 CDS SPN23F_21150 NC_011900.1 2055616 2056056 R DNA-binding protein complement(2055616..2056056) Streptococcus pneumoniae ATCC 700669 7328043 YP_002511954.1 CDS gpsA NC_011900.1 2056268 2057284 D catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate; NAD(P)H-dependent glycerol-3-phosphate dehydrogenase 2056268..2057284 Streptococcus pneumoniae ATCC 700669 7328044 YP_002511955.1 CDS hasC NC_011900.1 2057306 2058205 D UTP-glucose-1-phosphate uridylyltransferase 2057306..2058205 Streptococcus pneumoniae ATCC 700669 7328620 YP_002511956.1 CDS SPN23F_21180 NC_011900.1 2058277 2058954 R rhomboid family membrane protein complement(2058277..2058954) Streptococcus pneumoniae ATCC 700669 7328067 YP_002511957.1 CDS SPN23F_21190 NC_011900.1 2058938 2059477 R 5-formyltetrahydrofolate cyclo-ligase complement(2058938..2059477) Streptococcus pneumoniae ATCC 700669 7328045 YP_002511958.1 CDS SPN23F_21200 NC_011900.1 2059489 2060619 R peptidase complement(2059489..2060619) Streptococcus pneumoniae ATCC 700669 7328046 YP_002511959.1 CDS SPN23F_21210 NC_011900.1 2060687 2061385 R transferase complement(2060687..2061385) Streptococcus pneumoniae ATCC 700669 7328047 YP_002511960.1 CDS SPN23F_21220 NC_011900.1 2061615 2062526 R hypothetical protein complement(2061615..2062526) Streptococcus pneumoniae ATCC 700669 7328048 YP_002511961.1 CDS pbp1B NC_011900.1 2062591 2065056 R penicillin-binding protein 1B complement(2062591..2065056) Streptococcus pneumoniae ATCC 700669 7328049 YP_002511962.1 CDS tyrS NC_011900.1 2065198 2066454 D catalyzes the formation of tyrosyl-tRNA(Tyr) from tyrosine and tRNA(Tyr); tyrosyl-tRNA synthetase 2065198..2066454 Streptococcus pneumoniae ATCC 700669 7328454 YP_002511963.1 CDS SPN23F_21250 NC_011900.1 2066532 2068595 R cation transporting ATPase complement(2066532..2068595) Streptococcus pneumoniae ATCC 700669 7327658 YP_002511964.1 CDS SPN23F_21260 NC_011900.1 2068597 2068875 R hypothetical protein complement(2068597..2068875) Streptococcus pneumoniae ATCC 700669 7328050 YP_002511965.1 CDS SPN23F_21270 NC_011900.1 2069027 2069875 D ribosomal RNA large subunit methyltransferase A 2069027..2069875 Streptococcus pneumoniae ATCC 700669 7328051 YP_002511966.1 CDS SPN23F_21290 NC_011900.1 2070497 2071069 D hypothetical protein 2070497..2071069 Streptococcus pneumoniae ATCC 700669 7328052 YP_002511967.1 CDS glgP NC_011900.1 2072113 2074371 R glycogen phosphorylase complement(2072113..2074371) Streptococcus pneumoniae ATCC 700669 7328053 YP_002511968.1 CDS malQ NC_011900.1 2074397 2075914 R amylomaltase; acts to release glucose from maltodextrins; 4-alpha-glucanotransferase complement(2074397..2075914) Streptococcus pneumoniae ATCC 700669 7328599 YP_002511969.1 CDS malX NC_011900.1 2076464 2077735 D maltose/maltodextrin-binding protein precursor 2076464..2077735 Streptococcus pneumoniae ATCC 700669 7328118 YP_002511970.1 CDS malC NC_011900.1 2077846 2079138 D maltose/maltodextrin ABC transport system permease protein 2077846..2079138 Streptococcus pneumoniae ATCC 700669 7328120 YP_002511971.1 CDS malD NC_011900.1 2079140 2079982 D maltose/maltodextrin ABC transport system permease protein 2079140..2079982 Streptococcus pneumoniae ATCC 700669 7328116 YP_002511972.1 CDS malA NC_011900.1 2080235 2081035 D maltodextrose utilization protein MalA 2080235..2081035 Streptococcus pneumoniae ATCC 700669 7328117 YP_002511973.1 CDS malR NC_011900.1 2081045 2082031 D maltose operon transcriptional repressor 2081045..2082031 Streptococcus pneumoniae ATCC 700669 7328115 YP_002511974.1 CDS SPN23F_21380 NC_011900.1 2082216 2083472 R IS1167 transposase complement(2082216..2083472) Streptococcus pneumoniae ATCC 700669 7328119 YP_002511975.1 CDS SPN23F_21390 NC_011900.1 2083608 2084153 D May be non-coding repetitive sequence; repetitive protein 2083608..2084153 Streptococcus pneumoniae ATCC 700669 7328054 YP_002511976.1 CDS SPN23F_21400 NC_011900.1 2084195 2085136 R hypothetical protein complement(2084195..2085136) Streptococcus pneumoniae ATCC 700669 7328055 YP_002511977.1 CDS aspS NC_011900.1 2085114 2086877 R catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes; aspartyl-tRNA synthetase complement(2085114..2086877) Streptococcus pneumoniae ATCC 700669 7328056 YP_002511978.1 CDS SPN23F_21420 NC_011900.1 2086996 2087232 R hypothetical protein complement(2086996..2087232) Streptococcus pneumoniae ATCC 700669 7328671 YP_002511979.1 CDS SPN23F_21430 NC_011900.1 2087274 2087504 R hypothetical protein complement(2087274..2087504) Streptococcus pneumoniae ATCC 700669 7328057 YP_002511980.1 CDS SPN23F_21440 NC_011900.1 2087522 2088163 R May form pseudogene with downstream CDS; CAAX amino terminal protease family membrane protein complement(2087522..2088163) Streptococcus pneumoniae ATCC 700669 7328058 YP_002511981.1 CDS SPN23F_21450 NC_011900.1 2088175 2088897 R hypothetical protein complement(2088175..2088897) Streptococcus pneumoniae ATCC 700669 7328303 YP_002511982.1 CDS SPN23F_21460 NC_011900.1 2088900 2089097 R hypothetical protein complement(2088900..2089097) Streptococcus pneumoniae ATCC 700669 7328462 YP_002511983.1 CDS SPN23F_21470 NC_011900.1 2089097 2089303 R DNA-binding protein complement(2089097..2089303) Streptococcus pneumoniae ATCC 700669 7328463 YP_002511984.1 CDS SPN23F_21480 NC_011900.1 2089313 2089777 R hypothetical protein complement(2089313..2089777) Streptococcus pneumoniae ATCC 700669 7328464 YP_002511985.1 CDS SPN23F_21490 NC_011900.1 2089777 2089968 R hypothetical protein complement(2089777..2089968) Streptococcus pneumoniae ATCC 700669 7328465 YP_002511986.1 CDS hisS NC_011900.1 2089965 2091254 R catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG; histidyl-tRNA synthetase complement(2089965..2091254) Streptococcus pneumoniae ATCC 700669 7328466 YP_002511987.1 CDS SPN23F_21510 NC_011900.1 2091332 2092579 R Major Facilitator Superfamily protein complement(2091332..2092579) Streptococcus pneumoniae ATCC 700669 7328070 YP_002511988.1 CDS SPN23F_21520 NC_011900.1 2092796 2094142 D IS4-family transposase 2092796..2094142 Streptococcus pneumoniae ATCC 700669 7328467 YP_002511989.1 CDS SPN23F_21530 NC_011900.1 2094478 2095329 R DNA-binding protein complement(2094478..2095329) Streptococcus pneumoniae ATCC 700669 7328468 YP_002511990.1 CDS SPN23F_21540 NC_011900.1 2095382 2096335 R insertion sequence IS1239 transposase complement(2095382..2096335) Streptococcus pneumoniae ATCC 700669 7328469 YP_002511991.1 CDS SPN23F_21560 NC_011900.1 2096698 2097039 D hypothetical protein 2096698..2097039 Streptococcus pneumoniae ATCC 700669 7328470 YP_002511992.1 CDS ilvD NC_011900.1 2097248 2098951 R catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis; dihydroxy-acid dehydratase complement(2097248..2098951) Streptococcus pneumoniae ATCC 700669 7328471 YP_002511993.1 CDS SPN23F_21590 NC_011900.1 2099184 2100116 R transketolase subunit complement(2099184..2100116) Streptococcus pneumoniae ATCC 700669 7328083 YP_002511994.1 CDS SPN23F_21600 NC_011900.1 2100113 2100970 R transketolase subunit complement(2100113..2100970) Streptococcus pneumoniae ATCC 700669 7328472 YP_002511995.1 CDS ulaA NC_011900.1 2100974 2102320 R membrane component; functions with enzymes IIB (sgaB; ulaB) and IIA (sgaA; ulaC) enzyme I and HPr for anaerobic utilization and uptake of L-ascorbate; sgaTBA are regulated by yifQ as well as Crp and Fnr; PTS system ascorbate-specific transporter subunit IIC complement(2100974..2102320) Streptococcus pneumoniae ATCC 700669 7328473 YP_002511996.1 CDS SPN23F_21620 NC_011900.1 2102333 2102617 R sugar phosphotransferase system (PTS),lactose/cellobiose-specific family, IIB subunit protein complement(2102333..2102617) Streptococcus pneumoniae ATCC 700669 7328474 YP_002511997.1 CDS SPN23F_21630 NC_011900.1 2102621 2104651 R PTS multi-domain regulator complement(2102621..2104651) Streptococcus pneumoniae ATCC 700669 7328475 YP_002511998.1 CDS SPN23F_21640 NC_011900.1 2104842 2105849 D hypothetical protein 2104842..2105849 Streptococcus pneumoniae ATCC 700669 7328476 YP_002511999.1 CDS SPN23F_21650 NC_011900.1 2105852 2106052 D hypothetical protein 2105852..2106052 Streptococcus pneumoniae ATCC 700669 7328477 YP_002512000.1 CDS rpmF NC_011900.1 2106204 2106386 D some L32 proteins have zinc finger motifs consisting of CXXC while others do not; 50S ribosomal protein L32 2106204..2106386 Streptococcus pneumoniae ATCC 700669 7328478 YP_002512001.1 CDS rpmG NC_011900.1 2106402 2106551 D in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif; 50S ribosomal protein L33 2106402..2106551 Streptococcus pneumoniae ATCC 700669 7327497 YP_002512002.1 CDS SPN23F_21680 NC_011900.1 2107133 2108389 D transposase 2107133..2108389 Streptococcus pneumoniae ATCC 700669 7327498 YP_002512003.1 CDS pcpA NC_011900.1 2108466 2110451 R cell surface choline binding protein PcpA complement(2108466..2110451) Streptococcus pneumoniae ATCC 700669 7328479 YP_002512004.1 CDS gcnA NC_011900.1 2112435 2114315 R N-acetyl-beta-D-glucosaminidase complement(2112435..2114315) Streptococcus pneumoniae ATCC 700669 7328483 YP_002512005.1 CDS SPN23F_21750 NC_011900.1 2114309 2115178 R ROK family protein complement(2114309..2115178) Streptococcus pneumoniae ATCC 700669 7328590 YP_002512006.1 CDS SPN23F_21760 NC_011900.1 2115262 2117907 R glycosyl hydrolase complement(2115262..2117907) Streptococcus pneumoniae ATCC 700669 7328484 YP_002512007.1 CDS SPN23F_21770 NC_011900.1 2117998 2119278 R hypothetical protein complement(2117998..2119278) Streptococcus pneumoniae ATCC 700669 7328485 YP_002512008.1 CDS SPN23F_21780 NC_011900.1 2119449 2121533 D alpha-1,2-mannosidase 2119449..2121533 Streptococcus pneumoniae ATCC 700669 7328486 YP_002512009.1 CDS SPN23F_21790 NC_011900.1 2121573 2123252 R fucosidase complement(2121573..2123252) Streptococcus pneumoniae ATCC 700669 7328487 YP_002512010.1 CDS arcA NC_011900.1 2124008 2125237 D catalyzes the degradation of arginine to citruline and ammonia; arginine deiminase 2124008..2125237 Streptococcus pneumoniae ATCC 700669 7328488 YP_002512011.1 CDS arcB NC_011900.1 2125295 2126311 D catalyzes the formation of ornithine and carbamylphosphate from citrulline in the arginine catabolic pathway; ornithine carbamoyltransferase 2125295..2126311 Streptococcus pneumoniae ATCC 700669 7328652 YP_002512012.1 CDS arcC NC_011900.1 2126476 2127423 D catalyzes the reversible synthesis of carbamate and ATP from carbamoyl phosphate and ADP; carbamate kinase 2126476..2127423 Streptococcus pneumoniae ATCC 700669 7328653 YP_002512013.1 CDS SPN23F_21830 NC_011900.1 2127634 2129145 D C4-dicarboxylate anaerobic carrier protein 2127634..2129145 Streptococcus pneumoniae ATCC 700669 7328654 YP_002512014.1 CDS SPN23F_21840 NC_011900.1 2129167 2130498 D hypothetical protein 2129167..2130498 Streptococcus pneumoniae ATCC 700669 7328489 YP_002512015.1 CDS SPN23F_21880 NC_011900.1 2131831 2132730 R hypothetical protein complement(2131831..2132730) Streptococcus pneumoniae ATCC 700669 7328493 YP_002512016.1 CDS SPN23F_21890 NC_011900.1 2132860 2134011 R alcohol dehydrogenase complement(2132860..2134011) Streptococcus pneumoniae ATCC 700669 7328494 YP_002512017.1 CDS fucI NC_011900.1 2134157 2135923 R catalyzes the conversion of the aldose L-fucose into the corresponding ketose L-fuculose; L-fucose isomerase complement(2134157..2135923) Streptococcus pneumoniae ATCC 700669 7328495 YP_002512018.1 CDS SPN23F_21910 NC_011900.1 2135980 2139096 R exported glycosyl hydrolase complement(2135980..2139096) Streptococcus pneumoniae ATCC 700669 7328576 YP_002512019.1 CDS SPN23F_21920 NC_011900.1 2139106 2141400 R hypothetical protein complement(2139106..2141400) Streptococcus pneumoniae ATCC 700669 7328496 YP_002512020.1 CDS SPN23F_21930 NC_011900.1 2141459 2142259 R PTS system, IId component complement(2141459..2142259) Streptococcus pneumoniae ATCC 700669 7328497 YP_002512021.1 CDS SPN23F_21940 NC_011900.1 2142256 2143029 R PTS system, IIc component complement(2142256..2143029) Streptococcus pneumoniae ATCC 700669 7328498 YP_002512022.1 CDS SPN23F_21950 NC_011900.1 2143054 2143524 R PTS system, mannose-specific IIAB component complement(2143054..2143524) Streptococcus pneumoniae ATCC 700669 7328499 YP_002512023.1 CDS SPN23F_21960 NC_011900.1 2143515 2143958 R PTS system, IIa component complement(2143515..2143958) Streptococcus pneumoniae ATCC 700669 7328500 YP_002512024.1 CDS fucU NC_011900.1 2143939 2144379 R fuscose operon fucU protein complement(2143939..2144379) Streptococcus pneumoniae ATCC 700669 7328501 YP_002512025.1 CDS fucA NC_011900.1 2144391 2145029 R catalyzes the formation of glycerone phosphate and (S)-lactaldehyde from L-fuculose 1-phosphate; L-fuculose phosphate aldolase complement(2144391..2145029) Streptococcus pneumoniae ATCC 700669 7328578 YP_002512026.1 CDS fucK NC_011900.1 2145144 2146547 R fuculokinase complement(2145144..2146547) Streptococcus pneumoniae ATCC 700669 7328575 YP_002512027.1 CDS SPN23F_22000 NC_011900.1 2146723 2147496 D fucose phosphotransferase system repressor 2146723..2147496 Streptococcus pneumoniae ATCC 700669 7328577 YP_002512028.1 CDS adcA NC_011900.1 2148625 2150130 R zinc-binding protein AdcA precursor complement(2148625..2150130) Streptococcus pneumoniae ATCC 700669 7328502 YP_002512029.1 CDS SPN23F_22020 NC_011900.1 2150140 2150946 R ABC transporter permease complement(2150140..2150946) Streptococcus pneumoniae ATCC 700669 7328633 YP_002512030.1 CDS SPN23F_22030 NC_011900.1 2150939 2151643 R ABC transporter ATP-binding protein complement(2150939..2151643) Streptococcus pneumoniae ATCC 700669 7328503 YP_002512031.1 CDS SPN23F_22040 NC_011900.1 2151643 2152083 R MarR family transcriptional regulator complement(2151643..2152083) Streptococcus pneumoniae ATCC 700669 7328504 YP_002512032.1 CDS dltD NC_011900.1 2152238 2153506 R D-alanyl-lipoteichoic acid biosynthesis protein complement(2152238..2153506) Streptococcus pneumoniae ATCC 700669 7328505 YP_002512033.1 CDS dltC NC_011900.1 2153499 2153738 R D-alanyl carrier protein subunit; involved in the incorporation of D-alanine into membrane-associated D-alanyl-lipoteichoic acid; D-alanyl carrier protein is the acceptor of activated D-alanine which it donates to a membrane acceptor(D-alanyl transferase) for incorporation into membrane lipoteichoic acid; D-alanine--poly(phosphoribitol) ligase subunit 2 complement(2153499..2153738) Streptococcus pneumoniae ATCC 700669 7329236 YP_002512034.1 CDS dltB NC_011900.1 2153752 2154996 R activated D-alanine transport protein complement(2153752..2154996) Streptococcus pneumoniae ATCC 700669 7329235 YP_002512035.1 CDS dltA NC_011900.1 2154993 2156543 R transfers D-alanine to the D-alanyl carrier protein during the incorporation of D-alanine into lipoteichoic acid; D-alanine--poly(phosphoribitol) ligase subunit 1 complement(2154993..2156543) Streptococcus pneumoniae ATCC 700669 7329234 YP_002512036.1 CDS SPN23F_22100 NC_011900.1 2156564 2156695 R hypothetical protein complement(2156564..2156695) Streptococcus pneumoniae ATCC 700669 7329233 YP_002512037.1 CDS SPN23F_22110 NC_011900.1 2157009 2157914 R major facilitator family transport protein complement(2157009..2157914) Streptococcus pneumoniae ATCC 700669 7328506 YP_002512038.1 CDS SPN23F_22150 NC_011900.1 2161027 2161614 D hypothetical protein 2161027..2161614 Streptococcus pneumoniae ATCC 700669 7328508 YP_002512039.1 CDS SPN23F_22160 NC_011900.1 2161701 2161904 R May be affected by BOX element. May be truncated.; hypothetical protein complement(2161701..2161904) Streptococcus pneumoniae ATCC 700669 7328509 YP_002512040.1 CDS glpF1 NC_011900.1 2162201 2162905 R glycerol uptake facilitator protein 1 complement(2162201..2162905) Streptococcus pneumoniae ATCC 700669 7328510 YP_002512041.1 CDS glpO NC_011900.1 2162975 2164801 R alpha-glycerophosphate oxidase complement(2162975..2164801) Streptococcus pneumoniae ATCC 700669 7328608 YP_002512042.1 CDS glpK NC_011900.1 2164843 2166351 R Converts glycerol and ADP to glycerol-3-phosphate and ADP; glycerol kinase complement(2164843..2166351) Streptococcus pneumoniae ATCC 700669 7328610 YP_002512043.1 CDS SPN23F_22210 NC_011900.1 2166510 2167919 R DNA-binding protein complement(2166510..2167919) Streptococcus pneumoniae ATCC 700669 7328609 YP_002512044.1 CDS hslO NC_011900.1 2168102 2168974 D becomes active under oxidative stress; four conserved cysteines bind a zinc atom when they are in the reduced state and the enzyme is inactive; oxidative stress results in oxidized cysteines, release of zinc, and binding of Hsp33 to aggregation-prone proteins; forms dimers and higher order oligomers; Hsp33-like chaperonin 2168102..2168974 Streptococcus pneumoniae ATCC 700669 7328511 YP_002512045.1 CDS SPN23F_22230 NC_011900.1 2168961 2169941 D tRNA-dihydrouridine synthase 2168961..2169941 Streptococcus pneumoniae ATCC 700669 7328512 YP_002512046.1 CDS cbpA NC_011900.1 2170171 2172795 R choline-binding surface protein A complement(2170171..2172795) Streptococcus pneumoniae ATCC 700669 7328513 YP_002512047.1 CDS SPN23F_22250 NC_011900.1 2172874 2173401 R isoprenylcysteine carboxyl methyltransferase (ICMT) family protein complement(2172874..2173401) Streptococcus pneumoniae ATCC 700669 7328861 YP_002512048.1 CDS SPN23F_22260 NC_011900.1 2173496 2174827 R two-component system, sensor histidine kinase complement(2173496..2174827) Streptococcus pneumoniae ATCC 700669 7328514 YP_002512049.1 CDS SPN23F_22270 NC_011900.1 2174824 2175477 R two-component system, response regulator complement(2174824..2175477) Streptococcus pneumoniae ATCC 700669 7328515 YP_002512050.1 CDS clpC NC_011900.1 2175798 2178230 R stress response-related Clp ATPase complement(2175798..2178230) Streptococcus pneumoniae ATCC 700669 7328516 YP_002512051.1 CDS ctsR NC_011900.1 2178232 2178690 R transcriptional regulator complement(2178232..2178690) Streptococcus pneumoniae ATCC 700669 7329195 YP_002512052.1 CDS SPN23F_22300 NC_011900.1 2178809 2179537 R ABC transporter ATP-binding protein complement(2178809..2179537) Streptococcus pneumoniae ATCC 700669 7329216 YP_002512053.1 CDS SPN23F_22310 NC_011900.1 2179537 2180544 R ABC transporter substrate-binding protein complement(2179537..2180544) Streptococcus pneumoniae ATCC 700669 7328517 YP_002512054.1 CDS SPN23F_22320 NC_011900.1 2180583 2181299 R ABC transporter permease complement(2180583..2181299) Streptococcus pneumoniae ATCC 700669 7328518 YP_002512055.1 CDS SPN23F_22330 NC_011900.1 2181304 2181594 R hypothetical protein complement(2181304..2181594) Streptococcus pneumoniae ATCC 700669 7328519 YP_002512056.1 CDS cbpD NC_011900.1 2181850 2183196 R choline binding protein D complement(2181850..2183196) Streptococcus pneumoniae ATCC 700669 7329486 YP_002512057.1 CDS veg NC_011900.1 2183285 2183551 R hypothetical protein complement(2183285..2183551) Streptococcus pneumoniae ATCC 700669 7329181 YP_002512058.1 CDS dnaC NC_011900.1 2183553 2184905 R unwinds double stranded DNA; replicative DNA helicase complement(2183553..2184905) Streptococcus pneumoniae ATCC 700669 7329428 YP_002512059.1 CDS rplI NC_011900.1 2184949 2185401 R in Escherichia coli this protein is wrapped around the base of the L1 stalk; 50S ribosomal protein L9 complement(2184949..2185401) Streptococcus pneumoniae ATCC 700669 7329239 YP_002512060.1 CDS SPN23F_22380 NC_011900.1 2185398 2187371 R DHH family protein complement(2185398..2187371) Streptococcus pneumoniae ATCC 700669 7327476 YP_002512061.1 CDS SPN23F_22390 NC_011900.1 2187507 2188055 R sigma 54 modulation protein / S30EA ribosomal protein complement(2187507..2188055) Streptococcus pneumoniae ATCC 700669 7328521 YP_002512062.1 CDS comFC NC_011900.1 2188135 2188797 R late competence protein complement(2188135..2188797) Streptococcus pneumoniae ATCC 700669 7328522 YP_002512063.1 CDS comFA NC_011900.1 2188794 2190092 R late competence protein complement(2188794..2190092) Streptococcus pneumoniae ATCC 700669 7329210 YP_002512064.1 CDS SPN23F_22420 NC_011900.1 2190148 2190783 D hypothetical protein 2190148..2190783 Streptococcus pneumoniae ATCC 700669 7329209 YP_002512065.1 CDS cysM NC_011900.1 2191068 2191988 D cysteine synthase 2191068..2191988 Streptococcus pneumoniae ATCC 700669 7328523 YP_002512066.1 CDS tsf NC_011900.1 2193606 2194646 R EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu; elongation factor Ts complement(2193606..2194646) Streptococcus pneumoniae ATCC 700669 7328526 YP_002512067.1 CDS rpsB NC_011900.1 2194725 2195504 R one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit; 30S ribosomal protein S2 complement(2194725..2195504) Streptococcus pneumoniae ATCC 700669 7327655 YP_002512068.1 CDS SPN23F_22490 NC_011900.1 2195728 2196906 R amidase complement(2195728..2196906) Streptococcus pneumoniae ATCC 700669 7329109 YP_002512069.1 CDS SPN23F_22500 NC_011900.1 2197000 2197494 R hypothetical protein complement(2197000..2197494) Streptococcus pneumoniae ATCC 700669 7328527 YP_002512070.1 CDS mreC NC_011900.1 2197494 2198312 R in some organisms this protein is a transmembrane protein while in others it is periplasmic; involved in some organisms with other components of the MreBCD complex and with penicillin binding proteins in the periplasm or cell wall; rod shape-determining protein MreC complement(2197494..2198312) Streptococcus pneumoniae ATCC 700669 7328528 YP_002512071.1 CDS SPN23F_22520 NC_011900.1 2198371 2199165 R cobalt transport protein complement(2198371..2199165) Streptococcus pneumoniae ATCC 700669 7328133 YP_002512072.1 CDS cbiO NC_011900.1 2199158 2199997 R with CbiNQ forms the ABC transporter for cobalt import; Streptococcus has two adjacent copies of this gene; cobalt transporter ATP-binding subunit complement(2199158..2199997) Streptococcus pneumoniae ATCC 700669 7328529 YP_002512073.1 CDS cbiO NC_011900.1 2199982 2200809 R with CbiNQ forms the ABC transporter for cobalt import; Streptococcus has two adjacent copies of this gene; cobalt transporter ATP-binding subunit complement(2199982..2200809) Streptococcus pneumoniae ATCC 700669 7328530 YP_002512074.1 CDS pgsA NC_011900.1 2200806 2201351 R CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase complement(2200806..2201351) Streptococcus pneumoniae ATCC 700669 7328531 YP_002512075.1 CDS SPN23F_22560 NC_011900.1 2201362 2202183 R hypothetical protein complement(2201362..2202183) Streptococcus pneumoniae ATCC 700669 7327840 YP_002512076.1 CDS SPN23F_22570 NC_011900.1 2202225 2203508 R protease complement(2202225..2203508) Streptococcus pneumoniae ATCC 700669 7328532 YP_002512077.1 CDS SPN23F_22580 NC_011900.1 2203505 2204755 R protease complement(2203505..2204755) Streptococcus pneumoniae ATCC 700669 7328533 YP_002512078.1 CDS SPN23F_22590 NC_011900.1 2204914 2205282 D hypothetical protein 2204914..2205282 Streptococcus pneumoniae ATCC 700669 7328534 YP_002512079.1 CDS recF NC_011900.1 2205285 2206382 D Required for DNA replication; binds preferentially to single-stranded, linear DNA; recombination protein F 2205285..2206382 Streptococcus pneumoniae ATCC 700669 7328535 YP_002512080.1 CDS guaB NC_011900.1 2206434 2207912 R catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate; inosine 5'-monophosphate dehydrogenase complement(2206434..2207912) Streptococcus pneumoniae ATCC 700669 7327443 YP_002512081.1 CDS trsA NC_011900.1 2208064 2209089 R catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; tryptophanyl-tRNA synthetase II complement(2208064..2209089) Streptococcus pneumoniae ATCC 700669 7328064 YP_002512082.1 CDS SPN23F_22630 NC_011900.1 2209295 2210917 D ABC transporter ATP-binding protein 2209295..2210917 Streptococcus pneumoniae ATCC 700669 7327652 YP_002512083.1 CDS SPN23F_22640 NC_011900.1 2210979 2213531 D hypothetical protein 2210979..2213531 Streptococcus pneumoniae ATCC 700669 7328536 YP_002512084.1 CDS SPN23F_22650 NC_011900.1 2214036 2214311 R hypothetical protein complement(2214036..2214311) Streptococcus pneumoniae ATCC 700669 7328537 YP_002512085.1 CDS SPN23F_22660 NC_011900.1 2214396 2215109 R hypothetical protein complement(2214396..2215109) Streptococcus pneumoniae ATCC 700669 7328538 YP_002512086.1 CDS SPN23F_22670 NC_011900.1 2215342 2215884 D TetR family transcriptional regulator 2215342..2215884 Streptococcus pneumoniae ATCC 700669 7328539 YP_002512087.1 CDS SPN23F_22680 NC_011900.1 2216127 2216879 R response regulator protein complement(2216127..2216879) Streptococcus pneumoniae ATCC 700669 7327607 YP_002512088.1 CDS SPN23F_22690 NC_011900.1 2216876 2218201 R sensor histidine kinase complement(2216876..2218201) Streptococcus pneumoniae ATCC 700669 7328543 YP_002512089.1 CDS comC2 NC_011900.1 2218222 2218347 R competence-stimulating peptide type 2 precursor (csp-2) complement(2218222..2218347) Streptococcus pneumoniae ATCC 700669 7328623 YP_002512090.1 CDS SPN23F_22710 NC_011900.1 2218629 2219108 R SPOUT methyltransferase family protein; crystal structure shows homodimer; in Escherichia coli this protein methylates pseudouridine at position 1915 of the 23S ribosomal RNA; rRNA large subunit methyltransferase complement(2218629..2219108) Streptococcus pneumoniae ATCC 700669 7327595 YP_002512091.1 CDS htrA NC_011900.1 2219291 2220472 D serine protease 2219291..2220472 Streptococcus pneumoniae ATCC 700669 7328624 YP_002512092.1 CDS parB NC_011900.1 2220530 2221288 D chromosome partitioning protein ParB 2220530..2221288 Streptococcus pneumoniae ATCC 700669 7328078 SPN23F_t01 tRNA tRNA-Glu NC_011900.1 16437 16508 D tRNA-Glu 16437..16508 Streptococcus pneumoniae ATCC 700669 7329211 SPN23F_t02 tRNA tRNA-Ala NC_011900.1 18357 18429 D tRNA-Ala 18357..18429 Streptococcus pneumoniae ATCC 700669 7329455 SPN23F_t03 tRNA tRNA-Asn NC_011900.1 21653 21726 D tRNA-Asn 21653..21726 Streptococcus pneumoniae ATCC 700669 7329457 SPN23F_t04 tRNA tRNA-Tyr NC_011900.1 761735 761815 D tRNA-Tyr 761735..761815 Streptococcus pneumoniae ATCC 700669 7327797 SPN23F_t05 tRNA tRNA-Gln NC_011900.1 761825 761896 D tRNA-Gln 761825..761896 Streptococcus pneumoniae ATCC 700669 7327640 SPN23F_t06 tRNA tRNA-Ser NC_011900.1 776382 776469 R tRNA-Ser complement(776382..776469) Streptococcus pneumoniae ATCC 700669 7329469 SPN23F_t07 tRNA tRNA-Thr NC_011900.1 908444 908516 D tRNA-Thr 908444..908516 Streptococcus pneumoniae ATCC 700669 7328932 SPN23F_t08 tRNA tRNA-Arg NC_011900.1 1120369 1120440 R tRNA-Arg complement(1120369..1120440) Streptococcus pneumoniae ATCC 700669 7327463 SPN23F_t09 tRNA tRNA-Arg NC_011900.1 1163401 1163472 R tRNA-Arg complement(1163401..1163472) Streptococcus pneumoniae ATCC 700669 7327716 SPN23F_t10 tRNA tRNA-Leu NC_011900.1 1541332 1541417 R tRNA-Leu complement(1541332..1541417) Streptococcus pneumoniae ATCC 700669 7328138 SPN23F_t11 tRNA tRNA-Lys NC_011900.1 1753180 1753252 D tRNA-Lys 1753180..1753252 Streptococcus pneumoniae ATCC 700669 7329345 SPN23F_t12 tRNA tRNA-Ser NC_011900.1 1866303 1866390 R tRNA-Ser complement(1866303..1866390) Streptococcus pneumoniae ATCC 700669 7328310 SPN23F_t13 tRNA tRNA-Ile NC_011900.1 1866397 1866470 R tRNA-Ile complement(1866397..1866470) Streptococcus pneumoniae ATCC 700669 7327633 SPN23F_t14 tRNA tRNA-Gly NC_011900.1 1866506 1866576 R tRNA-Gly complement(1866506..1866576) Streptococcus pneumoniae ATCC 700669 7327613 SPN23F_t15 tRNA tRNA-Phe NC_011900.1 1866596 1866668 R tRNA-Phe complement(1866596..1866668) Streptococcus pneumoniae ATCC 700669 7327608 SPN23F_t16 tRNA tRNA-Met NC_011900.1 1866672 1866745 R tRNA-Met complement(1866672..1866745) Streptococcus pneumoniae ATCC 700669 7327628 SPN23F_t17 tRNA tRNA-Ser NC_011900.1 1866756 1866845 R tRNA-Ser complement(1866756..1866845) Streptococcus pneumoniae ATCC 700669 7327624 SPN23F_t18 tRNA tRNA-Met NC_011900.1 1866856 1866929 R tRNA-Met complement(1866856..1866929) Streptococcus pneumoniae ATCC 700669 7327634 SPN23F_t19 tRNA tRNA-Met NC_011900.1 1866943 1867016 R tRNA-Met complement(1866943..1867016) Streptococcus pneumoniae ATCC 700669 7327625 SPN23F_t20 tRNA tRNA-Pro NC_011900.1 1867022 1867095 R tRNA-Pro complement(1867022..1867095) Streptococcus pneumoniae ATCC 700669 7327626 SPN23F_t21 tRNA tRNA-Arg NC_011900.1 1867111 1867184 R tRNA-Arg complement(1867111..1867184) Streptococcus pneumoniae ATCC 700669 7327630 SPN23F_t22 tRNA tRNA-Leu NC_011900.1 1867194 1867279 R tRNA-Leu complement(1867194..1867279) Streptococcus pneumoniae ATCC 700669 7327593 SPN23F_t23 tRNA tRNA-Gly NC_011900.1 1867287 1867358 R tRNA-Gly complement(1867287..1867358) Streptococcus pneumoniae ATCC 700669 7327616 SPN23F_t24 tRNA tRNA-Thr NC_011900.1 1867381 1867453 R tRNA-Thr complement(1867381..1867453) Streptococcus pneumoniae ATCC 700669 7327609 SPN23F_t25 tRNA tRNA-Leu NC_011900.1 1867472 1867553 R tRNA-Leu complement(1867472..1867553) Streptococcus pneumoniae ATCC 700669 7327637 SPN23F_t26 tRNA tRNA-Lys NC_011900.1 1867559 1867631 R tRNA-Lys complement(1867559..1867631) Streptococcus pneumoniae ATCC 700669 7327617 SPN23F_t27 tRNA tRNA-Asp NC_011900.1 1867656 1867728 R tRNA-Asp complement(1867656..1867728) Streptococcus pneumoniae ATCC 700669 7327622 SPN23F_t28 tRNA tRNA-Val NC_011900.1 1867731 1867803 R tRNA-Val complement(1867731..1867803) Streptococcus pneumoniae ATCC 700669 7327598 SPN23F_t29 tRNA tRNA-Ala NC_011900.1 1871026 1871098 R tRNA-Ala complement(1871026..1871098) Streptococcus pneumoniae ATCC 700669 7329477 SPN23F_t30 tRNA tRNA-Glu NC_011900.1 1872947 1873018 R tRNA-Glu complement(1872947..1873018) Streptococcus pneumoniae ATCC 700669 7329478 SPN23F_t31 tRNA tRNA-Cys NC_011900.1 1928016 1928086 D tRNA-Cys 1928016..1928086 Streptococcus pneumoniae ATCC 700669 7329104 SPN23F_t32 tRNA tRNA-Pro NC_011900.1 1965650 1965723 R tRNA-Pro complement(1965650..1965723) Streptococcus pneumoniae ATCC 700669 7327985 SPN23F_t33 tRNA tRNA-Arg NC_011900.1 1965739 1965812 R tRNA-Arg complement(1965739..1965812) Streptococcus pneumoniae ATCC 700669 7327631 SPN23F_t34 tRNA tRNA-Leu NC_011900.1 1965822 1965907 R tRNA-Leu complement(1965822..1965907) Streptococcus pneumoniae ATCC 700669 7327594 SPN23F_t35 tRNA tRNA-Gly NC_011900.1 1965915 1965986 R tRNA-Gly complement(1965915..1965986) Streptococcus pneumoniae ATCC 700669 7327618 SPN23F_t36 tRNA tRNA-Thr NC_011900.1 1966009 1966081 R tRNA-Thr complement(1966009..1966081) Streptococcus pneumoniae ATCC 700669 7327610 SPN23F_t37 tRNA tRNA-Leu NC_011900.1 1966100 1966181 R tRNA-Leu complement(1966100..1966181) Streptococcus pneumoniae ATCC 700669 7327638 SPN23F_t38 tRNA tRNA-Lys NC_011900.1 1966187 1966259 R tRNA-Lys complement(1966187..1966259) Streptococcus pneumoniae ATCC 700669 7327619 SPN23F_t39 tRNA tRNA-Asp NC_011900.1 1966284 1966356 R tRNA-Asp complement(1966284..1966356) Streptococcus pneumoniae ATCC 700669 7327623 SPN23F_t40 tRNA tRNA-Val NC_011900.1 1966359 1966431 R tRNA-Val complement(1966359..1966431) Streptococcus pneumoniae ATCC 700669 7327599 SPN23F_t41 tRNA tRNA-Ala NC_011900.1 1969654 1969726 R tRNA-Ala complement(1969654..1969726) Streptococcus pneumoniae ATCC 700669 7329480 SPN23F_t42 tRNA tRNA-Glu NC_011900.1 1971575 1971646 R tRNA-Glu complement(1971575..1971646) Streptococcus pneumoniae ATCC 700669 7329481 SPN23F_t43 tRNA tRNA-Leu NC_011900.1 2027319 2027402 R tRNA-Leu complement(2027319..2027402) Streptococcus pneumoniae ATCC 700669 7328032 SPN23F_t44 tRNA tRNA-Gln NC_011900.1 2027412 2027483 R tRNA-Gln complement(2027412..2027483) Streptococcus pneumoniae ATCC 700669 7327620 SPN23F_t45 tRNA tRNA-His NC_011900.1 2027497 2027569 R tRNA-His complement(2027497..2027569) Streptococcus pneumoniae ATCC 700669 7327602 SPN23F_t46 tRNA tRNA-Trp NC_011900.1 2027584 2027654 R tRNA-Trp complement(2027584..2027654) Streptococcus pneumoniae ATCC 700669 7327612 SPN23F_t47 tRNA tRNA-Tyr NC_011900.1 2027659 2027739 R tRNA-Tyr complement(2027659..2027739) Streptococcus pneumoniae ATCC 700669 7327639 SPN23F_t48 tRNA tRNA-Phe NC_011900.1 2027752 2027824 R tRNA-Phe complement(2027752..2027824) Streptococcus pneumoniae ATCC 700669 7327641 SPN23F_t49 tRNA tRNA-Met NC_011900.1 2027828 2027901 R tRNA-Met complement(2027828..2027901) Streptococcus pneumoniae ATCC 700669 7327629 SPN23F_t50 tRNA tRNA-Ser NC_011900.1 2027912 2028001 R tRNA-Ser complement(2027912..2028001) Streptococcus pneumoniae ATCC 700669 7327627 SPN23F_t51 tRNA tRNA-Ile NC_011900.1 2028084 2028157 R tRNA-Ile complement(2028084..2028157) Streptococcus pneumoniae ATCC 700669 7327635 SPN23F_t52 tRNA tRNA-Gly NC_011900.1 2028192 2028262 R tRNA-Gly complement(2028192..2028262) Streptococcus pneumoniae ATCC 700669 7327614 SPN23F_t53 tRNA tRNA-Val NC_011900.1 2028268 2028340 R tRNA-Val complement(2028268..2028340) Streptococcus pneumoniae ATCC 700669 7327611 SPN23F_t54 tRNA tRNA-Ala NC_011900.1 2031563 2031635 R tRNA-Ala complement(2031563..2031635) Streptococcus pneumoniae ATCC 700669 7329483 SPN23F_t55 tRNA tRNA-Glu NC_011900.1 2033484 2033555 R tRNA-Glu complement(2033484..2033555) Streptococcus pneumoniae ATCC 700669 7329484 SPN23F_t56 tRNA tRNA-Asn NC_011900.1 2215925 2215998 R tRNA-Asn complement(2215925..2215998) Streptococcus pneumoniae ATCC 700669 7328540 SPN23F_t57 tRNA tRNA-Glu NC_011900.1 2216004 2216075 R tRNA-Glu complement(2216004..2216075) Streptococcus pneumoniae ATCC 700669 7327597 SPN23F_t58 tRNA tRNA-Arg NC_011900.1 2218512 2218585 R tRNA-Arg complement(2218512..2218585) Streptococcus pneumoniae ATCC 700669 7329206 SPN23F_r01 rRNA SPN23F_r01 NC_011900.1 16806 18218 D 16S ribosomal RNA 16806..18218 Streptococcus pneumoniae ATCC 700669 7327603 SPN23F_r02 rRNA SPN23F_r02 NC_011900.1 18554 21455 D 23S ribosomal RNA 18554..21455 Streptococcus pneumoniae ATCC 700669 7327587 SPN23F_r03 rRNA SPN23F_r03 NC_011900.1 21525 21672 D 5S ribosomal RNA 21525..21672 Streptococcus pneumoniae ATCC 700669 7329456 SPN23F_r04 rRNA SPN23F_r04 NC_011900.1 1867807 1867930 R 5S ribosomal RNA complement(1867807..1867930) Streptococcus pneumoniae ATCC 700669 7327642 SPN23F_r05 rRNA SPN23F_r05 NC_011900.1 1868002 1870901 R 23S ribosomal RNA complement(1868002..1870901) Streptococcus pneumoniae ATCC 700669 7329476 SPN23F_r06 rRNA SPN23F_r06 NC_011900.1 1871237 1872649 R 16S ribosomal RNA complement(1871237..1872649) Streptococcus pneumoniae ATCC 700669 7327588 SPN23F_r07 rRNA SPN23F_r07 NC_011900.1 1966435 1966558 R 5S ribosomal RNA complement(1966435..1966558) Streptococcus pneumoniae ATCC 700669 7327643 SPN23F_r08 rRNA SPN23F_r08 NC_011900.1 1966630 1969529 R 23S ribosomal RNA complement(1966630..1969529) Streptococcus pneumoniae ATCC 700669 7329479 SPN23F_r09 rRNA SPN23F_r09 NC_011900.1 1969865 1971277 R 16S ribosomal RNA complement(1969865..1971277) Streptococcus pneumoniae ATCC 700669 7327589 SPN23F_r10 rRNA SPN23F_r10 NC_011900.1 2028344 2028467 R 5S ribosomal RNA complement(2028344..2028467) Streptococcus pneumoniae ATCC 700669 7327644 SPN23F_r11 rRNA SPN23F_r11 NC_011900.1 2028539 2031438 R 23S ribosomal RNA complement(2028539..2031438) Streptococcus pneumoniae ATCC 700669 7329482 SPN23F_r12 rRNA SPN23F_r12 NC_011900.1 2031774 2033186 R 16S ribosomal RNA complement(2031774..2033186) Streptococcus pneumoniae ATCC 700669 7327590