-- dump date 20140620_084442 -- class Genbank::CDS -- table cds -- table main -- field 1 id -- field 2 GI -- field 3 GeneID -- field 4 chrom_position -- field 5 chromosome -- field 6 codon_start -- field 7 contig -- field 8 description -- field 9 end_pos -- field 10 gene -- field 11 gene_id -- field 12 name -- field 13 organism -- field 14 product -- field 15 protein_id -- field 16 start_pos -- field 17 strand -- field 18 taxid -- field 19 type -- header -- id GI GeneID chrom_position chromosome codon_start contig description end_pos gene gene_id name organism product protein_id start_pos strand taxid type YP_001834718.1 182682971 6217988 197..1558 1 NC_010582.1 binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication; can also affect transcription of multiple genes including itself.; chromosomal replication initiation protein 1558 dnaA 6217988 dnaA Streptococcus pneumoniae CGSP14 chromosomal replication initiation protein YP_001834718.1 197 D 516950 CDS YP_001834719.1 182682972 6217096 1717..2853 1 NC_010582.1 binds the polymerase to DNA and acts as a sliding clamp; DNA polymerase III subunit beta 2853 dnaN 6217096 dnaN Streptococcus pneumoniae CGSP14 DNA polymerase III subunit beta YP_001834719.1 1717 D 516950 CDS YP_001834720.1 182682973 6218106 2864..3112 1 NC_010582.1 hypothetical protein 3112 6218106 SPCG_0003 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001834720.1 2864 D 516950 CDS YP_001834721.1 182682974 6217056 3187..4311 1 NC_010582.1 translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1; GTP-dependent nucleic acid-binding protein EngD 4311 6217056 SPCG_0004 Streptococcus pneumoniae CGSP14 GTP-dependent nucleic acid-binding protein EngD YP_001834721.1 3187 D 516950 CDS YP_001834722.1 182682975 6216548 4382..4951 1 NC_010582.1 Enables the recycling of peptidyl-tRNAs produced at termination of translation; peptidyl-tRNA hydrolase 4951 pth 6216548 pth Streptococcus pneumoniae CGSP14 peptidyl-tRNA hydrolase YP_001834722.1 4382 D 516950 CDS YP_001834723.1 182682976 6217213 4952..8461 1 NC_010582.1 transcription-repair coupling factor 8461 mfd 6217213 mfd Streptococcus pneumoniae CGSP14 transcription-repair coupling factor YP_001834723.1 4952 D 516950 CDS YP_001834724.1 182682977 6217872 8519..8785 1 NC_010582.1 S4 domain-containing protein 8785 6217872 SPCG_0007 Streptococcus pneumoniae CGSP14 S4 domain-containing protein YP_001834724.1 8519 D 516950 CDS YP_001834725.1 182682978 6218256 8778..9146 1 NC_010582.1 hypothetical protein 9146 6218256 SPCG_0008 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001834725.1 8778 D 516950 CDS YP_001834726.1 182682979 6217895 9197..10534 1 NC_010582.1 hypothetical protein 10534 6217895 SPCG_0009 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001834726.1 9197 D 516950 CDS YP_001834727.1 182682980 6217938 10531..11808 1 NC_010582.1 mesJ/ycf62 family protein 11808 6217938 SPCG_0010 Streptococcus pneumoniae CGSP14 mesJ/ycf62 family protein YP_001834727.1 10531 D 516950 CDS YP_001834728.1 182682981 6218208 11812..12354 1 NC_010582.1 hypoxanthine-guanine phosphoribosyltransferase 12354 hgt 6218208 hgt Streptococcus pneumoniae CGSP14 hypoxanthine-guanine phosphoribosyltransferase YP_001834728.1 11812 D 516950 CDS YP_001834729.1 182682982 6217470 12370..14328 1 NC_010582.1 cell division protein FtsH 14328 ftsH 6217470 ftsH Streptococcus pneumoniae CGSP14 cell division protein FtsH YP_001834729.1 12370 D 516950 CDS YP_001834730.1 182682983 6217343 14450..14929 1 NC_010582.1 transcriptional regulator ComX1 14929 comX1 6217343 comX1 Streptococcus pneumoniae CGSP14 transcriptional regulator ComX1 YP_001834730.1 14450 D 516950 CDS YP_001834731.1 182682984 6218358 20396..20743 1 NC_010582.1 IS630-Spn1, transposase Orf1 20743 6218358 SPCG_0014 Streptococcus pneumoniae CGSP14 IS630-Spn1, transposase Orf1 YP_001834731.1 20396 D 516950 CDS YP_001834732.1 182682985 6217131 21451..21588 1 NC_010582.1 hypothetical protein 21588 6217131 SPCG_0015 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001834732.1 21451 D 516950 CDS YP_001834733.1 182682986 6216806 complement(21494..21598) 1 NC_010582.1 hypothetical protein 21598 6216806 SPCG_0016 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001834733.1 21494 R 516950 CDS YP_001834734.1 182682987 6216591 complement(21822..22028) 1 NC_010582.1 hypothetical protein 22028 6216591 SPCG_0017 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001834734.1 21822 R 516950 CDS YP_001834735.1 182682988 6217393 22338..22580 1 NC_010582.1 hypothetical protein 22580 6217393 SPCG_0018 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001834735.1 22338 D 516950 CDS YP_001834736.1 182682989 6218204 22769..24097 1 NC_010582.1 catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis; adenylosuccinate synthetase 24097 purA 6218204 purA Streptococcus pneumoniae CGSP14 adenylosuccinate synthetase YP_001834736.1 22769 D 516950 CDS YP_001834737.1 182682990 6216687 24298..24765 1 NC_010582.1 cytidine/deoxycytidylate deaminase family protein 24765 6216687 SPCG_0020 Streptococcus pneumoniae CGSP14 cytidine/deoxycytidylate deaminase family protein YP_001834737.1 24298 D 516950 CDS YP_001834738.1 182682991 6216809 24951..25394 1 NC_010582.1 catalyzes the formation of dUMP from dUTP; deoxyuridine 5'-triphosphate nucleotidohydrolase 25394 dut 6216809 dut Streptococcus pneumoniae CGSP14 deoxyuridine 5'-triphosphate nucleotidohydrolase YP_001834738.1 24951 D 516950 CDS YP_001834739.1 182682992 6217586 25354..25911 1 NC_010582.1 hypothetical protein 25911 6217586 SPCG_0022 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001834739.1 25354 D 516950 CDS YP_001834740.1 182682993 6217224 26024..27286 1 NC_010582.1 Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents; DNA repair protein RadA 27286 radA 6217224 radA Streptococcus pneumoniae CGSP14 DNA repair protein RadA YP_001834740.1 26024 D 516950 CDS YP_001834741.1 182682994 6216566 27290..27856 1 NC_010582.1 hypothetical protein 27856 6216566 SPCG_0024 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001834741.1 27290 D 516950 CDS YP_001834742.1 182682995 6216463 27877..28221 1 NC_010582.1 hypothetical protein 28221 6216463 SPCG_0025 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001834742.1 27877 D 516950 CDS YP_001834743.1 182682996 6217960 28203..28754 1 NC_010582.1 hypothetical protein 28754 6217960 SPCG_0026 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001834743.1 28203 D 516950 CDS YP_001834744.1 182682997 6216711 28730..29569 1 NC_010582.1 IS3-Spn1, transposase 29569 6216711 SPCG_0027 Streptococcus pneumoniae CGSP14 IS3-Spn1, transposase YP_001834744.1 28730 D 516950 CDS YP_001834745.1 182682998 6217011 29575..30135 1 NC_010582.1 repair protein 30135 6217011 SPCG_0028 Streptococcus pneumoniae CGSP14 repair protein YP_001834745.1 29575 D 516950 CDS YP_001834746.1 182682999 6217204 30229..31248 1 NC_010582.1 catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP; ribose-phosphate pyrophosphokinase 31248 prsA 6217204 prsA Streptococcus pneumoniae CGSP14 ribose-phosphate pyrophosphokinase YP_001834746.1 30229 D 516950 CDS YP_001834747.1 182683000 6217998 31366..31719 1 NC_010582.1 hypothetical protein 31719 6217998 SPCG_0030 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001834747.1 31366 D 516950 CDS YP_001834748.1 182683001 6216459 31938..32120 1 NC_010582.1 competence-induced protein Ccs16 32120 6216459 SPCG_0031 Streptococcus pneumoniae CGSP14 competence-induced protein Ccs16 YP_001834748.1 31938 D 516950 CDS YP_001834749.1 182683002 6218058 32865..35534 1 NC_010582.1 has 3'-5' exonuclease, 5'-3' exonuclease and 5'-3'polymerase activities, primarily functions to fill gaps during DNA replication and repair; DNA polymerase I 35534 polA 6218058 polA Streptococcus pneumoniae CGSP14 DNA polymerase I YP_001834749.1 32865 D 516950 CDS YP_001834750.1 182683003 6216513 35619..36056 1 NC_010582.1 hypothetical protein 36056 6216513 SPCG_0033 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001834750.1 35619 D 516950 CDS YP_001834751.1 182683004 6216871 complement(35958..36563) 1 NC_010582.1 hypothetical protein 36563 6216871 SPCG_0034 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001834751.1 35958 R 516950 CDS YP_001834752.1 182683005 6217805 complement(36511..37533) 1 NC_010582.1 membrane protein 37533 6217805 SPCG_0035 Streptococcus pneumoniae CGSP14 membrane protein YP_001834752.1 36511 R 516950 CDS YP_001834753.1 182683006 6216531 37670..38839 1 NC_010582.1 catalyzes the transamination of the aromatic amino acid forming a ketoacid; first step in aromatic amino acid degradation in lactococci; aromatic amino acid aminotransferase 38839 6216531 SPCG_0036 Streptococcus pneumoniae CGSP14 aromatic amino acid aminotransferase YP_001834753.1 37670 D 516950 CDS YP_001834754.1 182683008 6216885 complement(38770..39486) 1 NC_010582.1 hypothetical protein 39486 6216885 SPCG_0037 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001834754.1 38770 R 516950 CDS YP_001834755.1 182683007 6216507 38836..39606 1 NC_010582.1 involved in DNA repair and RecFOR pathway recombination; RecFOR proteins displace ssDNA-binding protein and facilitate the production of RecA-coated ssDNA; DNA repair protein RecO 39606 recO 6216507 recO Streptococcus pneumoniae CGSP14 DNA repair protein RecO YP_001834755.1 38836 D 516950 CDS YP_001834756.1 182683009 6216645 39603..40595 1 NC_010582.1 involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsY; glycerol-3-phosphate acyltransferase PlsX 40595 plsX 6216645 plsX Streptococcus pneumoniae CGSP14 glycerol-3-phosphate acyltransferase PlsX YP_001834756.1 39603 D 516950 CDS YP_001834757.1 182683010 6217801 40601..40834 1 NC_010582.1 acyl carrier protein 40834 acpP 6217801 acpP Streptococcus pneumoniae CGSP14 acyl carrier protein YP_001834757.1 40601 D 516950 CDS YP_001834758.1 182683011 6216829 40877..40969 1 NC_010582.1 degenerate transposase 40969 6216829 SPCG_0041 Streptococcus pneumoniae CGSP14 degenerate transposase YP_001834758.1 40877 D 516950 CDS YP_001834759.1 182683012 6218182 41079..41171 1 NC_010582.1 degenerate transposase 41171 6218182 SPCG_0042 Streptococcus pneumoniae CGSP14 degenerate transposase YP_001834759.1 41079 D 516950 CDS YP_001834760.1 182683013 6216830 41373..41603 1 NC_010582.1 bacteriocin BlpU 41603 6216830 SPCG_0043 Streptococcus pneumoniae CGSP14 bacteriocin BlpU YP_001834760.1 41373 D 516950 CDS YP_001834761.1 182683014 6217909 42291..44471 1 NC_010582.1 competence factor transporting ATP-binding protein/permease ComA 44471 comA 6217909 comA Streptococcus pneumoniae CGSP14 competence factor transporting ATP-binding protein/permease ComA YP_001834761.1 42291 D 516950 CDS YP_001834762.1 182683015 6217322 44484..45833 1 NC_010582.1 competence factor transport protein ComB 45833 comB 6217322 comB Streptococcus pneumoniae CGSP14 competence factor transport protein ComB YP_001834762.1 44484 D 516950 CDS YP_001834763.1 182683016 6216461 45961..46710 1 NC_010582.1 catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis; SAICAR synthase; phosphoribosylaminoimidazole-succinocarboxamide synthase 46710 purC 6216461 purC Streptococcus pneumoniae CGSP14 phosphoribosylaminoimidazole-succinocarboxamide synthase YP_001834763.1 45961 D 516950 CDS YP_001834764.1 182683017 6216689 46909..50637 1 NC_010582.1 phosphoribosylformylglycinamidine synthase 50637 purL 6216689 purL Streptococcus pneumoniae CGSP14 phosphoribosylformylglycinamidine synthase YP_001834764.1 46909 D 516950 CDS YP_001834765.1 182683018 6217300 50730..52172 1 NC_010582.1 Catalyzes first step of the de novo purine nucleotide biosynthetic pathway; amidophosphoribosyltransferase 52172 purF 6217300 purF Streptococcus pneumoniae CGSP14 amidophosphoribosyltransferase YP_001834765.1 50730 D 516950 CDS YP_001834766.1 182683019 6217762 52209..53231 1 NC_010582.1 catalyzes the formation of 1-(5-phosphoribosyl)-5-aminoimidazole from 2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in purine biosynthesis; phosphoribosylaminoimidazole synthetase 53231 purM 6217762 purM Streptococcus pneumoniae CGSP14 phosphoribosylaminoimidazole synthetase YP_001834766.1 52209 D 516950 CDS YP_001834767.1 182683020 6217005 53228..53773 1 NC_010582.1 glycinamide ribonucleotide transformylase; GAR Tfase; catalyzes the synthesis of 5'-phosphoribosylformylglycinamide from 5'-phosphoribosylglycinamide and 10-formyltetrahydrofolate; PurN requires formyl folate for the reaction unlike PurT which uses formate; phosphoribosylglycinamide formyltransferase 53773 purN 6217005 purN Streptococcus pneumoniae CGSP14 phosphoribosylglycinamide formyltransferase YP_001834767.1 53228 D 516950 CDS YP_001834768.1 182683021 6218179 53857..54366 1 NC_010582.1 vanZ protein 54366 vanZ 6218179 vanZ Streptococcus pneumoniae CGSP14 vanZ protein YP_001834768.1 53857 D 516950 CDS YP_001834769.1 182683022 6217203 54370..55938 1 NC_010582.1 involved in de novo purine biosynthesis; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 55938 purH 6217203 purH Streptococcus pneumoniae CGSP14 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase YP_001834769.1 54370 D 516950 CDS YP_001834770.1 182683023 6217176 56060..57322 1 NC_010582.1 catalyzes the formation of N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-D-ribosylamine and glycine in purine biosynthesis; phosphoribosylamine--glycine ligase 57322 purD 6217176 purD Streptococcus pneumoniae CGSP14 phosphoribosylamine--glycine ligase YP_001834770.1 56060 D 516950 CDS YP_001834771.1 182683024 6218509 57579..57695 1 NC_010582.1 hypothetical protein 57695 6218509 SPCG_0054 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001834771.1 57579 D 516950 CDS YP_001834772.1 182683025 6217140 57692..58213 1 NC_010582.1 phosphoribosylaminoimidazole carboxylase catalytic subunit 58213 purE 6217140 purE Streptococcus pneumoniae CGSP14 phosphoribosylaminoimidazole carboxylase catalytic subunit YP_001834772.1 57692 D 516950 CDS YP_001834773.1 182683026 6216646 58161..59291 1 NC_010582.1 With PurE catalyzes the conversion of aminoimidazole ribonucleotide to carboxyaminoimidazole ribonucleotide in the de novo purine nucleotide biosynthetic pathway; phosphoribosylaminoimidazole carboxylase ATPase subunit 59291 purK 6216646 purK Streptococcus pneumoniae CGSP14 phosphoribosylaminoimidazole carboxylase ATPase subunit YP_001834773.1 58161 D 516950 CDS YP_001834774.1 182683027 6216617 59301..59528 1 NC_010582.1 hypothetical protein 59528 6216617 SPCG_0057 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001834774.1 59301 D 516950 CDS YP_001834775.1 182683028 6216808 59591..60889 1 NC_010582.1 Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide; adenylosuccinate lyase 60889 purB 6216808 purB Streptococcus pneumoniae CGSP14 adenylosuccinate lyase YP_001834775.1 59591 D 516950 CDS YP_001834776.1 182683029 6217476 complement(60944..64969) 1 NC_010582.1 beta-N-acetylhexosaminidase 64969 strH 6217476 strH Streptococcus pneumoniae CGSP14 beta-N-acetylhexosaminidase YP_001834776.1 60944 R 516950 CDS YP_001834777.1 182683030 6216564 complement(65196..65954) 1 NC_010582.1 GntR family transcriptional regulator 65954 6216564 SPCG_0060 Streptococcus pneumoniae CGSP14 GntR family transcriptional regulator YP_001834777.1 65196 R 516950 CDS YP_001834778.1 182683031 6216780 66260..68047 1 NC_010582.1 beta-galactosidase 68047 bgaC 6216780 bgaC Streptococcus pneumoniae CGSP14 beta-galactosidase YP_001834778.1 66260 D 516950 CDS YP_001834779.1 182683032 6217134 68044..68520 1 NC_010582.1 PTS system transporter subunit IIB 68520 6217134 SPCG_0062 Streptococcus pneumoniae CGSP14 PTS system transporter subunit IIB YP_001834779.1 68044 D 516950 CDS YP_001834780.1 182683033 6217406 68548..69453 1 NC_010582.1 PTS system transporter subunit IIC 69453 6217406 SPCG_0063 Streptococcus pneumoniae CGSP14 PTS system transporter subunit IIC YP_001834780.1 68548 D 516950 CDS YP_001834781.1 182683034 6216661 69425..70255 1 NC_010582.1 PTS system transporter subunit IID 70255 6216661 SPCG_0064 Streptococcus pneumoniae CGSP14 PTS system transporter subunit IID YP_001834781.1 69425 D 516950 CDS YP_001834782.1 182683035 6218180 70262..70666 1 NC_010582.1 PTS system transporter subunit IIA 70666 6218180 SPCG_0065 Streptococcus pneumoniae CGSP14 PTS system transporter subunit IIA YP_001834782.1 70262 D 516950 CDS YP_001834783.1 182683036 6217336 70964..72124 1 NC_010582.1 sugar isomerase 72124 agaS 6217336 agaS Streptococcus pneumoniae CGSP14 sugar isomerase YP_001834783.1 70964 D 516950 CDS YP_001834784.1 182683037 6218128 72246..73283 1 NC_010582.1 aldose 1-epimerase 73283 galM 6218128 galM Streptococcus pneumoniae CGSP14 aldose 1-epimerase YP_001834784.1 72246 D 516950 CDS YP_001834785.1 182683038 6218333 73490..74344 1 NC_010582.1 hypothetical protein 74344 6218333 SPCG_0068 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001834785.1 73490 D 516950 CDS YP_001834786.1 182683039 6217804 74494..74751 1 NC_010582.1 hypothetical protein 74751 6217804 SPCG_0069 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001834786.1 74494 D 516950 CDS YP_001834787.1 182683040 6216504 complement(75209..75505) 1 NC_010582.1 rhodanese-like domain-containing protein 75505 6216504 SPCG_0070 Streptococcus pneumoniae CGSP14 rhodanese-like domain-containing protein YP_001834787.1 75209 R 516950 CDS YP_001834788.1 182683041 6218221 complement(75495..75614) 1 NC_010582.1 hypothetical protein 75614 6218221 SPCG_0071 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001834788.1 75495 R 516950 CDS YP_001834789.1 182683042 6216671 75726..76490 1 NC_010582.1 phosphorylase Pnp/Udp family protein 76490 6216671 SPCG_0072 Streptococcus pneumoniae CGSP14 phosphorylase Pnp/Udp family protein YP_001834789.1 75726 D 516950 CDS YP_001834790.1 182683043 6218389 76746..76886 1 NC_010582.1 hypothetical protein 76886 6218389 SPCG_0073 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001834790.1 76746 D 516950 CDS YP_001834791.1 182683044 6218215 77055..78434 1 NC_010582.1 Trk family potassium uptake protein 78434 trkH 6218215 trkH Streptococcus pneumoniae CGSP14 Trk family potassium uptake protein YP_001834791.1 77055 D 516950 CDS YP_001834792.1 182683045 6217363 78427..79113 1 NC_010582.1 Trk family potassium uptake protein 79113 trkA 6217363 trkA Streptococcus pneumoniae CGSP14 Trk family potassium uptake protein YP_001834792.1 78427 D 516950 CDS YP_001834793.1 182683046 6216549 79248..79451 1 NC_010582.1 hypothetical protein 79451 6216549 SPCG_0076 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001834793.1 79248 D 516950 CDS YP_001834794.1 182683047 6216763 79513..80052 1 NC_010582.1 hypothetical protein 80052 6216763 SPCG_0077 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001834794.1 79513 D 516950 CDS YP_001834795.1 182683049 6217413 complement(79930..80499) 1 NC_010582.1 hypothetical protein 80499 6217413 SPCG_0079 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001834795.1 79930 R 516950 CDS YP_001834796.1 182683048 6216586 80119..80529 1 NC_010582.1 hypothetical protein 80529 6216586 SPCG_0078 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001834796.1 80119 D 516950 CDS YP_001834797.1 182683050 6217051 80721..84131 1 NC_010582.1 cell wall surface anchor family protein 84131 6217051 SPCG_0080 Streptococcus pneumoniae CGSP14 cell wall surface anchor family protein YP_001834797.1 80721 D 516950 CDS YP_001834798.1 182683051 6216361 84298..84996 1 NC_010582.1 DNA-binding response regulator 84996 6216361 SPCG_0081 Streptococcus pneumoniae CGSP14 DNA-binding response regulator YP_001834798.1 84298 D 516950 CDS YP_001834799.1 182683052 6217048 84993..86045 1 NC_010582.1 sensor histidine kinase 86045 6217048 SPCG_0082 Streptococcus pneumoniae CGSP14 sensor histidine kinase YP_001834799.1 84993 D 516950 CDS YP_001834800.1 182683053 6216729 86240..86851 1 NC_010582.1 primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination; 30S ribosomal protein S4 86851 rpsD 6216729 rpsD Streptococcus pneumoniae CGSP14 30S ribosomal protein S4 YP_001834800.1 86240 D 516950 CDS YP_001834801.1 182683054 6217248 complement(87072..87167) 1 NC_010582.1 hypothetical protein 87167 6217248 SPCG_0084 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001834801.1 87072 R 516950 CDS YP_001834802.1 182683055 6217999 87238..87507 1 NC_010582.1 hypothetical protein 87507 6217999 SPCG_0085 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001834802.1 87238 D 516950 CDS YP_001834803.1 182683056 6216981 87587..87682 1 NC_010582.1 hypothetical protein 87682 6216981 SPCG_0086 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001834803.1 87587 D 516950 CDS YP_001834804.1 182683057 6216842 87971..88930 1 NC_010582.1 ABC transporter permease 88930 6216842 SPCG_0087 Streptococcus pneumoniae CGSP14 ABC transporter permease YP_001834804.1 87971 D 516950 CDS YP_001834805.1 182683058 6217903 88893..89867 1 NC_010582.1 ABC transporter permease 89867 6217903 SPCG_0088 Streptococcus pneumoniae CGSP14 ABC transporter permease YP_001834805.1 88893 D 516950 CDS YP_001834806.1 182683059 6217165 89908..91446 1 NC_010582.1 ABC transporter substrate-binding protein 91446 6217165 SPCG_0089 Streptococcus pneumoniae CGSP14 ABC transporter substrate-binding protein YP_001834806.1 89908 D 516950 CDS YP_001834807.1 182683060 6217459 91718..92704 1 NC_010582.1 hypothetical protein 92704 6217459 SPCG_0090 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001834807.1 91718 D 516950 CDS YP_001834808.1 182683061 6216832 92886..93839 1 NC_010582.1 hypothetical protein 93839 6216832 SPCG_0091 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001834808.1 92886 D 516950 CDS YP_001834809.1 182683062 6217955 complement(93911..94975) 1 NC_010582.1 hypothetical protein 94975 6217955 SPCG_0092 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001834809.1 93911 R 516950 CDS YP_001834810.1 182683063 6217187 complement(95038..96000) 1 NC_010582.1 hypothetical protein 96000 6217187 SPCG_0093 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001834810.1 95038 R 516950 CDS YP_001834811.1 182683064 6217233 complement(95942..96535) 1 NC_010582.1 hypothetical protein 96535 6217233 SPCG_0094 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001834811.1 95942 R 516950 CDS YP_001834812.1 182683065 6217599 complement(96522..96848) 1 NC_010582.1 hypothetical protein 96848 6217599 SPCG_0095 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001834812.1 96522 R 516950 CDS YP_001834813.1 182683066 6217027 complement(96987..98153) 1 NC_010582.1 transporter 98153 6217027 SPCG_0096 Streptococcus pneumoniae CGSP14 transporter YP_001834813.1 96987 R 516950 CDS YP_001834814.1 182683067 6216970 98211..99368 1 NC_010582.1 glycosyl transferase family protein 99368 6216970 SPCG_0097 Streptococcus pneumoniae CGSP14 glycosyl transferase family protein YP_001834814.1 98211 D 516950 CDS YP_001834815.1 182683068 6216716 99410..101260 1 NC_010582.1 capsular polysaccharide biosynthesis protein 101260 6216716 SPCG_0098 Streptococcus pneumoniae CGSP14 capsular polysaccharide biosynthesis protein YP_001834815.1 99410 D 516950 CDS YP_001834816.1 182683069 6217206 complement(101346..101603) 1 NC_010582.1 hypothetical protein 101603 6217206 SPCG_0099 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001834816.1 101346 R 516950 CDS YP_001834817.1 182683070 6217230 complement(101653..102285) 1 NC_010582.1 HAD superfamily hydrolase 102285 6217230 SPCG_0100 Streptococcus pneumoniae CGSP14 HAD superfamily hydrolase YP_001834817.1 101653 R 516950 CDS YP_001834818.1 182683071 6217058 complement(102307..103179) 1 NC_010582.1 L-serine dehydratase, iron-sulfur-dependent subunit alpha 103179 6217058 SPCG_0101 Streptococcus pneumoniae CGSP14 L-serine dehydratase, iron-sulfur-dependent subunit alpha YP_001834818.1 102307 R 516950 CDS YP_001834819.1 182683072 6217020 complement(103188..103859) 1 NC_010582.1 L-serine dehydratase, iron-sulfur-dependent subunit beta 103859 6217020 SPCG_0102 Streptococcus pneumoniae CGSP14 L-serine dehydratase, iron-sulfur-dependent subunit beta YP_001834819.1 103188 R 516950 CDS YP_001834820.1 182683073 6216471 104101..104688 1 NC_010582.1 lysM domain-containing protein 104688 6216471 SPCG_0103 Streptococcus pneumoniae CGSP14 lysM domain-containing protein YP_001834820.1 104101 D 516950 CDS YP_001834821.1 182683074 6216590 complement(104740..105060) 1 NC_010582.1 hypothetical protein 105060 6216590 SPCG_0104 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001834821.1 104740 R 516950 CDS YP_001834822.1 182683075 6216990 105486..105773 1 NC_010582.1 bacteriocin 105773 6216990 SPCG_0105 Streptococcus pneumoniae CGSP14 bacteriocin YP_001834822.1 105486 D 516950 CDS YP_001834823.1 182683076 6217679 105792..107933 1 NC_010582.1 hypothetical protein 107933 6217679 SPCG_0106 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001834823.1 105792 D 516950 CDS YP_001834824.1 182683077 6216805 107930..108571 1 NC_010582.1 amino acid ABC transporter ATP-binding protein 108571 6216805 SPCG_0107 Streptococcus pneumoniae CGSP14 amino acid ABC transporter ATP-binding protein YP_001834824.1 107930 D 516950 CDS YP_001834825.1 182683078 6218028 108676..109584 1 NC_010582.1 amino acid ABC transporter periplasmic amino acid-binding protein 109584 6218028 SPCG_0108 Streptococcus pneumoniae CGSP14 amino acid ABC transporter periplasmic amino acid-binding protein YP_001834825.1 108676 D 516950 CDS YP_001834826.1 182683079 6216710 109550..110020 1 NC_010582.1 argininosuccinate synthase, truncation 110020 6216710 SPCG_0109 Streptococcus pneumoniae CGSP14 argininosuccinate synthase, truncation YP_001834826.1 109550 D 516950 CDS YP_001834827.1 182683080 6216848 complement(110309..111208) 1 NC_010582.1 hypothetical protein 111208 6216848 SPCG_0110 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001834827.1 110309 R 516950 CDS YP_001834828.1 182683081 6217397 111626..111976 1 NC_010582.1 transporter truncation 111976 6217397 SPCG_0111 Streptococcus pneumoniae CGSP14 transporter truncation YP_001834828.1 111626 D 516950 CDS YP_001834829.1 182683082 6217023 111954..112325 1 NC_010582.1 hypothetical protein 112325 6217023 SPCG_0112 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001834829.1 111954 D 516950 CDS YP_001834830.1 182683083 6218027 112919..113044 1 NC_010582.1 hypothetical protein 113044 6218027 SPCG_0113 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001834830.1 112919 D 516950 CDS YP_001834831.1 182683084 6216980 113427..114485 1 NC_010582.1 hypothetical protein 114485 6216980 SPCG_0114 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001834831.1 113427 D 516950 CDS YP_001834832.1 182683085 6217607 114800..115777 1 NC_010582.1 hypothetical protein 115777 6217607 SPCG_0115 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001834832.1 114800 D 516950 CDS YP_001834833.1 182683086 6217627 116135..116509 1 NC_010582.1 hypothetical protein 116509 6217627 SPCG_0116 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001834833.1 116135 D 516950 CDS YP_001834834.1 182683087 6217369 116717..117619 1 NC_010582.1 hypothetical protein 117619 6217369 SPCG_0117 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001834834.1 116717 D 516950 CDS YP_001834835.1 182683088 6217167 117642..118007 1 NC_010582.1 hypothetical protein 118007 6217167 SPCG_0118 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001834835.1 117642 D 516950 CDS YP_001834836.1 182683089 6217249 117974..118732 1 NC_010582.1 hypothetical protein 118732 6217249 SPCG_0119 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001834836.1 117974 D 516950 CDS YP_001834837.1 182683090 6217682 120255..122084 1 NC_010582.1 surface protein A 122084 pspA 6217682 pspA Streptococcus pneumoniae CGSP14 surface protein A YP_001834837.1 120255 D 516950 CDS YP_001834838.1 182683091 6218108 122431..123606 1 NC_010582.1 catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs; tRNA-specific 2-thiouridylase MnmA 123606 mnmA 6218108 mnmA Streptococcus pneumoniae CGSP14 tRNA-specific 2-thiouridylase MnmA YP_001834838.1 122431 D 516950 CDS YP_001834839.1 182683092 6216519 123720..124202 1 NC_010582.1 mutT/nudix family protein 124202 6216519 SPCG_0122 Streptococcus pneumoniae CGSP14 mutT/nudix family protein YP_001834839.1 123720 D 516950 CDS YP_001834840.1 182683093 6217926 124212..126125 1 NC_010582.1 GidA; glucose-inhibited cell division protein A; involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U) of the wobble uridine base in some tRNAs; tRNA uridine 5-carboxymethylaminomethyl modification protein GidA 126125 gidA 6217926 gidA Streptococcus pneumoniae CGSP14 tRNA uridine 5-carboxymethylaminomethyl modification protein GidA YP_001834840.1 124212 D 516950 CDS YP_001834841.1 182683094 6218372 complement(126478..128157) 1 NC_010582.1 metallo-beta-lactamase superfamily protein 128157 6218372 SPCG_0124 Streptococcus pneumoniae CGSP14 metallo-beta-lactamase superfamily protein YP_001834841.1 126478 R 516950 CDS YP_001834842.1 182683095 6216866 complement(128159..128392) 1 NC_010582.1 hypothetical protein 128392 6216866 SPCG_0125 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001834842.1 128159 R 516950 CDS YP_001834843.1 182683096 6218232 128672..128779 1 NC_010582.1 hypothetical protein 128779 6218232 SPCG_0126 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001834843.1 128672 D 516950 CDS YP_001834844.1 182683097 6218092 complement(128802..128963) 1 NC_010582.1 competence-induced protein Ccs1, truncated 128963 6218092 SPCG_0127 Streptococcus pneumoniae CGSP14 competence-induced protein Ccs1, truncated YP_001834844.1 128802 R 516950 CDS YP_001834845.1 182683098 6217827 complement(129210..129362) 1 NC_010582.1 hypothetical protein 129362 6217827 SPCG_0128 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001834845.1 129210 R 516950 CDS YP_001834846.1 182683099 6217645 complement(129364..129549) 1 NC_010582.1 hypothetical protein 129549 6217645 SPCG_0129 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001834846.1 129364 R 516950 CDS YP_001834847.1 182683100 6216557 129727..130410 1 NC_010582.1 hypothetical protein 130410 6216557 SPCG_0130 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001834847.1 129727 D 516950 CDS YP_001834848.1 182683101 6217942 130407..130844 1 NC_010582.1 ribosomal-protein-alanine acetyltransferase 130844 rimI 6217942 rimI Streptococcus pneumoniae CGSP14 ribosomal-protein-alanine acetyltransferase YP_001834848.1 130407 D 516950 CDS YP_001834849.1 182683102 6218065 130834..131844 1 NC_010582.1 in most organisms, only the N-terminal domain is present in a single polypeptide; in some archaea this domain is fused to a kinase domain; this gene is essential for growth in Escherichia coli and Bacillus subtilis; the secreted glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins; the Pyrococcus structure shows DNA-binding properties, iron-binding, ATP-binding, and AP endonuclease activity; DNA-binding/iron metalloprotein/AP endonuclease 131844 gcp 6218065 gcp Streptococcus pneumoniae CGSP14 DNA-binding/iron metalloprotein/AP endonuclease YP_001834849.1 130834 D 516950 CDS YP_001834850.1 182683103 6216794 complement(131884..132270) 1 NC_010582.1 degenerate transposase 132270 6216794 SPCG_0133 Streptococcus pneumoniae CGSP14 degenerate transposase YP_001834850.1 131884 R 516950 CDS YP_001834851.1 182683104 6218161 complement(132477..133325) 1 NC_010582.1 degenerate transposase 133325 6218161 SPCG_0134 Streptococcus pneumoniae CGSP14 degenerate transposase YP_001834851.1 132477 R 516950 CDS YP_001834852.1 182683105 6216733 134450..135013 1 NC_010582.1 hypothetical protein 135013 6216733 SPCG_0135 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001834852.1 134450 D 516950 CDS YP_001834853.1 182683106 6216838 135141..135602 1 NC_010582.1 glycosyl transferase family protein 135602 epsG 6216838 epsG Streptococcus pneumoniae CGSP14 glycosyl transferase family protein YP_001834853.1 135141 D 516950 CDS YP_001834854.1 182683107 6218211 135626..136579 1 NC_010582.1 glycosyl transferase family protein 136579 6218211 SPCG_0137 Streptococcus pneumoniae CGSP14 glycosyl transferase family protein YP_001834854.1 135626 D 516950 CDS YP_001834855.1 182683108 6217010 136589..138205 1 NC_010582.1 ABC transporter ATP-binding protein 138205 6217010 SPCG_0138 Streptococcus pneumoniae CGSP14 ABC transporter ATP-binding protein YP_001834855.1 136589 D 516950 CDS YP_001834856.1 182683109 6218120 138129..139070 1 NC_010582.1 hypothetical protein 139070 6218120 SPCG_0139 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001834856.1 138129 D 516950 CDS YP_001834857.1 182683110 6217670 139099..140637 1 NC_010582.1 hypothetical protein 140637 6217670 SPCG_0140 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001834857.1 139099 D 516950 CDS YP_001834858.1 182683111 6217043 140643..141398 1 NC_010582.1 hypothetical protein 141398 6217043 SPCG_0141 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001834858.1 140643 D 516950 CDS YP_001834859.1 182683112 6218369 141411..142583 1 NC_010582.1 UDP-glucose dehydrogenase 142583 ugd 6218369 ugd Streptococcus pneumoniae CGSP14 UDP-glucose dehydrogenase YP_001834859.1 141411 D 516950 CDS YP_001834860.1 182683113 6217542 142954..143841 1 NC_010582.1 transcriptional regulator 143841 mutR 6217542 mutR Streptococcus pneumoniae CGSP14 transcriptional regulator YP_001834860.1 142954 D 516950 CDS YP_001834861.1 182683114 6217298 144111..144236 1 NC_010582.1 bacteriocin 144236 6217298 SPCG_0144 Streptococcus pneumoniae CGSP14 bacteriocin YP_001834861.1 144111 D 516950 CDS YP_001834862.1 182683115 6218217 144296..147211 1 NC_010582.1 lantibiotic biosynthesis protein 147211 6218217 SPCG_0145 Streptococcus pneumoniae CGSP14 lantibiotic biosynthesis protein YP_001834862.1 144296 D 516950 CDS YP_001834863.1 182683116 6218205 147195..148472 1 NC_010582.1 lantibiotic biosynthesis protein 148472 6218205 SPCG_0146 Streptococcus pneumoniae CGSP14 lantibiotic biosynthesis protein YP_001834863.1 147195 D 516950 CDS YP_001834864.1 182683117 6217420 148501..149757 1 NC_010582.1 lantibiotic efflux protein 149757 6217420 SPCG_0147 Streptococcus pneumoniae CGSP14 lantibiotic efflux protein YP_001834864.1 148501 D 516950 CDS YP_001834865.1 182683118 6218050 149836..150513 1 NC_010582.1 hypothetical protein 150513 6218050 SPCG_0148 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001834865.1 149836 D 516950 CDS YP_001834866.1 182683119 6216971 150525..151190 1 NC_010582.1 hypothetical protein 151190 6216971 SPCG_0149 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001834866.1 150525 D 516950 CDS YP_001834867.1 182683120 6216893 151259..152488 1 NC_010582.1 hypothetical protein 152488 6216893 SPCG_0150 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001834867.1 151259 D 516950 CDS YP_001834868.1 182683121 6217407 152943..153557 1 NC_010582.1 hypothetical protein 153557 6217407 SPCG_0151 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001834868.1 152943 D 516950 CDS YP_001834869.1 182683122 6216483 153661..154491 1 NC_010582.1 ABC transporter substrate-binding protein 154491 6216483 SPCG_0152 Streptococcus pneumoniae CGSP14 ABC transporter substrate-binding protein YP_001834869.1 153661 D 516950 CDS YP_001834870.1 182683123 6218225 154645..155499 1 NC_010582.1 lipoprotein 155499 6218225 SPCG_0153 Streptococcus pneumoniae CGSP14 lipoprotein YP_001834870.1 154645 D 516950 CDS YP_001834871.1 182683124 6218260 155596..156969 1 NC_010582.1 hypothetical protein 156969 6218260 SPCG_0154 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001834871.1 155596 D 516950 CDS YP_001834872.1 182683125 6216484 156962..158023 1 NC_010582.1 ABC transporter ATP-binding protein 158023 6216484 SPCG_0155 Streptococcus pneumoniae CGSP14 ABC transporter ATP-binding protein YP_001834872.1 156962 D 516950 CDS YP_001834873.1 182683126 6217952 158025..158717 1 NC_010582.1 ABC transporter permease 158717 6217952 SPCG_0156 Streptococcus pneumoniae CGSP14 ABC transporter permease YP_001834873.1 158025 D 516950 CDS YP_001834874.1 182683127 6216497 158833..159606 1 NC_010582.1 transcriptional activator Rgg/GadR/MutR family protein 159606 6216497 SPCG_0157 Streptococcus pneumoniae CGSP14 transcriptional activator Rgg/GadR/MutR family protein YP_001834874.1 158833 D 516950 CDS YP_001834875.1 182683128 6217254 159788..159907 1 NC_010582.1 hypothetical protein 159907 6217254 SPCG_0158 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001834875.1 159788 D 516950 CDS YP_001834876.1 182683129 6216498 159930..160244 1 NC_010582.1 hypothetical protein 160244 6216498 SPCG_0159 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001834876.1 159930 D 516950 CDS YP_001834877.1 182683130 6217223 160260..160646 1 NC_010582.1 hypothetical protein 160646 6217223 SPCG_0160 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001834877.1 160260 D 516950 CDS YP_001834878.1 182683131 6217925 160675..162060 1 NC_010582.1 hypothetical protein 162060 6217925 SPCG_0161 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001834878.1 160675 D 516950 CDS YP_001834879.1 182683132 6217565 162238..163443 1 NC_010582.1 Tn916, transcriptional regulator 163443 6217565 SPCG_0162 Streptococcus pneumoniae CGSP14 Tn916, transcriptional regulator YP_001834879.1 162238 D 516950 CDS YP_001834880.1 182683133 6217684 163486..163707 1 NC_010582.1 hypothetical protein 163707 6217684 SPCG_0163 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001834880.1 163486 D 516950 CDS YP_001834881.1 182683134 6216474 163824..164321 1 NC_010582.1 hypothetical protein 164321 6216474 SPCG_0164 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001834881.1 163824 D 516950 CDS YP_001834882.1 182683135 6216528 164296..164802 1 NC_010582.1 hypothetical protein 164802 6216528 SPCG_0165 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001834882.1 164296 D 516950 CDS YP_001834883.1 182683136 6217931 164735..167233 1 NC_010582.1 hypothetical protein 167233 6217931 SPCG_0166 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001834883.1 164735 D 516950 CDS YP_001834884.1 182683137 6216624 167236..169413 1 NC_010582.1 hypothetical protein 169413 6216624 SPCG_0167 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001834884.1 167236 D 516950 CDS YP_001834885.1 182683138 6217606 169410..170411 1 NC_010582.1 hypothetical protein 170411 6217606 SPCG_0168 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001834885.1 169410 D 516950 CDS YP_001834886.1 182683139 6216655 170408..171343 1 NC_010582.1 hypothetical protein 171343 6216655 SPCG_0169 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001834886.1 170408 D 516950 CDS YP_001834887.1 182683140 6218265 171618..171704 1 NC_010582.1 regulates the transcription of tet(M) by attenuation; tetracycline resistance determinant leader peptide 171704 6218265 SPCG_0170 Streptococcus pneumoniae CGSP14 tetracycline resistance determinant leader peptide YP_001834887.1 171618 D 516950 CDS YP_001834888.1 182683141 6216664 171705..173639 1 NC_010582.1 tetracycline resistance protein TetM 173639 6216664 SPCG_0171 Streptococcus pneumoniae CGSP14 tetracycline resistance protein TetM YP_001834888.1 171705 D 516950 CDS YP_001834889.1 182683142 6217896 174564..175301 1 NC_010582.1 rRNA methylase 175301 6217896 SPCG_0172 Streptococcus pneumoniae CGSP14 rRNA methylase YP_001834889.1 174564 D 516950 CDS YP_001834890.1 182683143 6216916 175656..176210 1 NC_010582.1 resolvase 176210 6216916 SPCG_0173 Streptococcus pneumoniae CGSP14 resolvase YP_001834890.1 175656 D 516950 CDS YP_001834891.1 182683144 6218176 176214..179132 1 NC_010582.1 transposase 179132 6218176 SPCG_0174 Streptococcus pneumoniae CGSP14 transposase YP_001834891.1 176214 D 516950 CDS YP_001834892.1 182683145 6217621 complement(179188..179427) 1 NC_010582.1 hypothetical protein 179427 6217621 SPCG_0175 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001834892.1 179188 R 516950 CDS YP_001834893.1 182683146 6217172 179923..180354 1 NC_010582.1 hypothetical protein 180354 6217172 SPCG_0176 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001834893.1 179923 D 516950 CDS YP_001834894.1 182683147 6216701 180351..180581 1 NC_010582.1 hypothetical protein 180581 6216701 SPCG_0177 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001834894.1 180351 D 516950 CDS YP_001834895.1 182683148 6218246 181042..181245 1 NC_010582.1 hypothetical protein 181245 6218246 SPCG_0178 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001834895.1 181042 D 516950 CDS YP_001834896.1 182683149 6216887 181327..182544 1 NC_010582.1 hypothetical protein 182544 6216887 SPCG_0179 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001834896.1 181327 D 516950 CDS YP_001834897.1 182683150 6218511 182961..184277 1 NC_010582.1 hypothetical protein 184277 6218511 SPCG_0180 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001834897.1 182961 D 516950 CDS YP_001834898.1 182683151 6217698 184315..184518 1 NC_010582.1 hypothetical protein 184518 6217698 SPCG_0181 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001834898.1 184315 D 516950 CDS YP_001834899.1 182683152 6216678 complement(184713..185375) 1 NC_010582.1 hypothetical protein 185375 6216678 SPCG_0182 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001834899.1 184713 R 516950 CDS YP_001834900.1 182683153 6216973 185632..186213 1 NC_010582.1 hypothetical protein 186213 6216973 SPCG_0183 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001834900.1 185632 D 516950 CDS YP_001834901.1 182683154 6218326 186159..186761 1 NC_010582.1 has a stimulatory effect on the ribonucleotide reductase activity of NrdH with NrdEF; flavoprotein NrdI 186761 6218326 SPCG_0184 Streptococcus pneumoniae CGSP14 flavoprotein NrdI YP_001834901.1 186159 D 516950 CDS YP_001834902.1 182683155 6216769 complement(187054..188361) 1 NC_010582.1 hypothetical protein 188361 6216769 SPCG_0185 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001834902.1 187054 R 516950 CDS YP_001834903.1 182683156 6216978 complement(188626..189084) 1 NC_010582.1 hypothetical protein 189084 6216978 SPCG_0186 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001834903.1 188626 R 516950 CDS YP_001834904.1 182683157 6216633 complement(189081..189602) 1 NC_010582.1 hypothetical protein 189602 6216633 SPCG_0187 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001834904.1 189081 R 516950 CDS YP_001834905.1 182683158 6218250 189877..191826 1 NC_010582.1 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. Promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex; DNA mismatch repair protein 191826 mutL 6218250 mutL Streptococcus pneumoniae CGSP14 DNA mismatch repair protein YP_001834905.1 189877 D 516950 CDS YP_001834906.1 182683159 6217429 complement(192151..192618) 1 NC_010582.1 RibE; 6,7-diimethyl-8-ribityllumazine synthase; DMRL synthase; lumazine synthase; beta subunit of riboflavin synthase; condenses 5-amino-6-(1'-D)-ribityl-amino-2,4(1H,3H)-pyrimidinedione with L-3,4-dihydrohy-2-butanone-4-phosphate to generate 6,6-dimethyl-8-lumazine (DMRL); riboflavin synthase then uses 2 molecules of DMRL to produce riboflavin (vitamin B12); involved in the last steps of riboflavin biosynthesis; forms a 60mer (icosahedral shell) in both Bacillus subtilis and Escherichia coli; in Bacillus subtilis this 60mer is associated with the riboflavin synthase subunit (alpha) while in Escherichia coli it is not; 6,7-dimethyl-8-ribityllumazine synthase 192618 ribH 6217429 ribH Streptococcus pneumoniae CGSP14 6,7-dimethyl-8-ribityllumazine synthase YP_001834906.1 192151 R 516950 CDS YP_001834907.1 182683160 6217181 complement(192619..193854) 1 NC_010582.1 3,4-dihydroxy-2-butanone 4-phosphate synthase 193854 ribA 6217181 ribA Streptococcus pneumoniae CGSP14 3,4-dihydroxy-2-butanone 4-phosphate synthase YP_001834907.1 192619 R 516950 CDS YP_001834908.1 182683161 6216914 complement(193844..194479) 1 NC_010582.1 catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine; riboflavin synthase subunit alpha 194479 ribC 6216914 ribC Streptococcus pneumoniae CGSP14 riboflavin synthase subunit alpha YP_001834908.1 193844 R 516950 CDS YP_001834909.1 182683162 6217884 complement(194464..195564) 1 NC_010582.1 riboflavin biosynthesis protein RibD 195564 ribD 6217884 ribD Streptococcus pneumoniae CGSP14 riboflavin biosynthesis protein RibD YP_001834909.1 194464 R 516950 CDS YP_001834910.1 182683163 6216651 195970..196563 1 NC_010582.1 plays an essential role in ATP-dependent branch migration of the Holliday junction; Holliday junction DNA helicase RuvA 196563 ruvA 6216651 ruvA Streptococcus pneumoniae CGSP14 Holliday junction DNA helicase RuvA YP_001834910.1 195970 D 516950 CDS YP_001834911.1 182683165 6217953 complement(196219..196776) 1 NC_010582.1 hypothetical protein 196776 6217953 SPCG_0194 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001834911.1 196219 R 516950 CDS YP_001834912.1 182683164 6218185 196573..197136 1 NC_010582.1 DNA-3-methyladenine glycosylase I 197136 tag 6218185 tag Streptococcus pneumoniae CGSP14 DNA-3-methyladenine glycosylase I YP_001834912.1 196573 D 516950 CDS YP_001834913.1 182683166 6216995 197133..197810 1 NC_010582.1 hypothetical protein 197810 6216995 SPCG_0196 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001834913.1 197133 D 516950 CDS YP_001834914.1 182683167 6216767 complement(197965..198996) 1 NC_010582.1 mccC family protein 198996 6216767 SPCG_0197 Streptococcus pneumoniae CGSP14 mccC family protein YP_001834914.1 197965 R 516950 CDS YP_001834915.1 182683168 6218401 complement(199184..199279) 1 NC_010582.1 hypothetical protein 199279 6218401 SPCG_0198 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001834915.1 199184 R 516950 CDS YP_001834916.1 182683169 6217849 complement(199251..199955) 1 NC_010582.1 hypothetical protein 199955 6217849 SPCG_0199 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001834916.1 199251 R 516950 CDS YP_001834917.1 182683170 6217007 complement(199946..200890) 1 NC_010582.1 magnesium transporter CorA family protein 200890 6217007 SPCG_0200 Streptococcus pneumoniae CGSP14 magnesium transporter CorA family protein YP_001834917.1 199946 R 516950 CDS YP_001834918.1 182683171 6218209 200989..203853 1 NC_010582.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate; excinuclease ABC subunit A 203853 uvrA 6218209 uvrA Streptococcus pneumoniae CGSP14 excinuclease ABC subunit A YP_001834918.1 200989 D 516950 CDS YP_001834919.1 182683172 6217045 203846..204907 1 NC_010582.1 peptidase M24 family protein 204907 pepP 6217045 pepP Streptococcus pneumoniae CGSP14 peptidase M24 family protein YP_001834919.1 203846 D 516950 CDS YP_001834920.1 182683173 6217294 205039..205437 1 NC_010582.1 the anti-alpha factor Spx interacts with RNA polymerase alpha subunit C-terminal domain in a region that interacts with the sigma 70 subunit and may interfere with activation of promoters; in Bacillus subtilis this protein is a substrate for ClpXP protease; blocks transcription of the competence regulatory gene encoded by the srf operon; regulates a number of genes involved in thiol homeostasis including trxA and trxB; monomeric member of ArsC family of proteins; does not bind DNA; contains a disulfide bond between C10 and C13 which may sense disulfide stress; transcriptional regulator Spx 205437 spxA 6217294 spxA Streptococcus pneumoniae CGSP14 transcriptional regulator Spx YP_001834920.1 205039 D 516950 CDS YP_001834921.1 182683174 6217365 205503..206072 1 NC_010582.1 hypothetical protein 206072 6217365 SPCG_0204 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001834921.1 205503 D 516950 CDS YP_001834922.1 182683175 6217026 206159..206425 1 NC_010582.1 hypothetical protein 206425 6217026 SPCG_0205 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001834922.1 206159 D 516950 CDS YP_001834923.1 182683176 6218464 206429..206848 1 NC_010582.1 similar to RuvC resolvase with substantial differences; NMR structural information suggests this protein is monomeric; unknown cellular function; Holliday junction resolvase-like protein 206848 6218464 SPCG_0206 Streptococcus pneumoniae CGSP14 Holliday junction resolvase-like protein YP_001834923.1 206429 D 516950 CDS YP_001834924.1 182683177 6218276 206864..207169 1 NC_010582.1 hypothetical protein 207169 6218276 SPCG_0207 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001834924.1 206864 D 516950 CDS YP_001834925.1 182683178 6217331 207471..208727 1 NC_010582.1 dihydrofolate synthetase 208727 folC 6217331 folC Streptococcus pneumoniae CGSP14 dihydrofolate synthetase YP_001834925.1 207471 D 516950 CDS YP_001834926.1 182683179 6217044 208724..209269 1 NC_010582.1 hypothetical protein 209269 6217044 SPCG_0209 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001834926.1 208724 D 516950 CDS YP_001834927.1 182683180 6217079 209415..210947 1 NC_010582.1 cardiolipin synthetase 210947 cls 6217079 cls Streptococcus pneumoniae CGSP14 cardiolipin synthetase YP_001834927.1 209415 D 516950 CDS YP_001834928.1 182683181 6218488 211187..212743 1 NC_010582.1 competence-induced protein Ccs4 212743 6218488 SPCG_0211 Streptococcus pneumoniae CGSP14 competence-induced protein Ccs4 YP_001834928.1 211187 D 516950 CDS YP_001834929.1 182683182 6216881 212857..215070 1 NC_010582.1 Catalyzes the reduction of nucleoside 5'-triphosphates to 2'-deoxynucleoside 5'-triphosphates; anaerobic ribonucleoside triphosphate reductase 215070 6216881 SPCG_0212 Streptococcus pneumoniae CGSP14 anaerobic ribonucleoside triphosphate reductase YP_001834929.1 212857 D 516950 CDS YP_001834930.1 182683183 6217918 215082..215222 1 NC_010582.1 hypothetical protein 215222 6217918 SPCG_0213 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001834930.1 215082 D 516950 CDS YP_001834931.1 182683184 6216520 215266..215772 1 NC_010582.1 acetyltransferase 215772 6216520 SPCG_0214 Streptococcus pneumoniae CGSP14 acetyltransferase YP_001834931.1 215266 D 516950 CDS YP_001834932.1 182683185 6216965 215765..216355 1 NC_010582.1 anaerobic ribonucleoside-triphosphate reductase activating protein 216355 nrdD 6216965 nrdD Streptococcus pneumoniae CGSP14 anaerobic ribonucleoside-triphosphate reductase activating protein YP_001834932.1 215765 D 516950 CDS YP_001834933.1 182683186 6217324 216352..216969 1 NC_010582.1 hypothetical protein 216969 6217324 SPCG_0216 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001834933.1 216352 D 516950 CDS YP_001834934.1 182683187 6217037 217236..217544 1 NC_010582.1 NusE; involved in assembly of the 30S subunit; in the ribosome, this protein is involved in the binding of tRNA; in Escherichia coli this protein was also found to be involved in transcription antitermination; NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination; binding of NusB/S10 to boxA nucleates assembly of the antitermination complex; 30S ribosomal protein S10 217544 rpsJ 6217037 rpsJ Streptococcus pneumoniae CGSP14 30S ribosomal protein S10 YP_001834934.1 217236 D 516950 CDS YP_001834935.1 182683188 6218580 217760..218386 1 NC_010582.1 binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin; 50S ribosomal protein L3 218386 rplC 6218580 rplC Streptococcus pneumoniae CGSP14 50S ribosomal protein L3 YP_001834935.1 217760 D 516950 CDS YP_001834936.1 182683189 6216607 218411..219034 1 NC_010582.1 L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA; 50S ribosomal protein L4 219034 rplD 6216607 rplD Streptococcus pneumoniae CGSP14 50S ribosomal protein L4 YP_001834936.1 218411 D 516950 CDS YP_001834937.1 182683190 6217095 219034..219330 1 NC_010582.1 binds third domain of 23S rRNA and protein L29; part of exit tunnel; 50S ribosomal protein L23 219330 rplW 6217095 rplW Streptococcus pneumoniae CGSP14 50S ribosomal protein L23 YP_001834937.1 219034 D 516950 CDS YP_001834938.1 182683191 6217222 219348..220181 1 NC_010582.1 one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation; 50S ribosomal protein L2 220181 rplB 6217222 rplB Streptococcus pneumoniae CGSP14 50S ribosomal protein L2 YP_001834938.1 219348 D 516950 CDS YP_001834939.1 182683192 6217395 220273..220554 1 NC_010582.1 protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA; 30S ribosomal protein S19 220554 rpsS 6217395 rpsS Streptococcus pneumoniae CGSP14 30S ribosomal protein S19 YP_001834939.1 220273 D 516950 CDS YP_001834940.1 182683193 6216643 220566..220910 1 NC_010582.1 binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center; 50S ribosomal protein L22 220910 rplV 6216643 rplV Streptococcus pneumoniae CGSP14 50S ribosomal protein L22 YP_001834940.1 220566 D 516950 CDS YP_001834941.1 182683194 6217648 220923..221576 1 NC_010582.1 forms a complex with S10 and S14; binds the lower part of the 30S subunit head and the mRNA in the complete ribosome to position it for translation; 30S ribosomal protein S3 221576 rpsC 6217648 rpsC Streptococcus pneumoniae CGSP14 30S ribosomal protein S3 YP_001834941.1 220923 D 516950 CDS YP_001834942.1 182683195 6217644 221580..221993 1 NC_010582.1 located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e; 50S ribosomal protein L16 221993 rplP 6217644 rplP Streptococcus pneumoniae CGSP14 50S ribosomal protein L16 YP_001834942.1 221580 D 516950 CDS YP_001834943.1 182683196 6217636 222003..222209 1 NC_010582.1 one of the stabilizing components for the large ribosomal subunit; 50S ribosomal protein L29 222209 rpmC 6217636 rpmC Streptococcus pneumoniae CGSP14 50S ribosomal protein L29 YP_001834943.1 222003 D 516950 CDS YP_001834944.1 182683197 6217629 222234..222494 1 NC_010582.1 primary binding protein; helps mediate assembly; involved in translation fidelity; 30S ribosomal protein S17 222494 rpsQ 6217629 rpsQ Streptococcus pneumoniae CGSP14 30S ribosomal protein S17 YP_001834944.1 222234 D 516950 CDS YP_001834945.1 182683198 6217622 222520..222888 1 NC_010582.1 binds to the 23S rRNA between the centers for peptidyl transferase and GTPase; 50S ribosomal protein L14 222888 rplN 6217622 rplN Streptococcus pneumoniae CGSP14 50S ribosomal protein L14 YP_001834945.1 222520 D 516950 CDS YP_001834946.1 182683199 6217611 222966..223271 1 NC_010582.1 assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel; 50S ribosomal protein L24 223271 rplX 6217611 rplX Streptococcus pneumoniae CGSP14 50S ribosomal protein L24 YP_001834946.1 222966 D 516950 CDS YP_001834947.1 182683200 6217488 223295..223837 1 NC_010582.1 part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13; 50S ribosomal protein L5 223837 rplE 6217488 rplE Streptococcus pneumoniae CGSP14 50S ribosomal protein L5 YP_001834947.1 223295 D 516950 CDS YP_001834948.1 182683201 6218565 223855..224124 1 NC_010582.1 located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group do not appear to have the zinc-binding motif; 30S ribosomal protein S14 224124 rpsN 6218565 rpsN Streptococcus pneumoniae CGSP14 30S ribosomal protein S14 YP_001834948.1 223855 D 516950 CDS YP_001834949.1 182683202 6217591 224338..224736 1 NC_010582.1 binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; 30S ribosomal protein S8 224736 rpsH 6217591 rpsH Streptococcus pneumoniae CGSP14 30S ribosomal protein S8 YP_001834949.1 224338 D 516950 CDS YP_001834950.1 182683203 6217575 224928..225464 1 NC_010582.1 ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance; 50S ribosomal protein L6 225464 rplF 6217575 rplF Streptococcus pneumoniae CGSP14 50S ribosomal protein L6 YP_001834950.1 224928 D 516950 CDS YP_001834951.1 182683204 6217231 225509..225904 1 NC_010582.1 binds 5S rRNA along with protein L5 and L25; 50S ribosomal protein L18 225904 rplR 6217231 rplR Streptococcus pneumoniae CGSP14 50S ribosomal protein L18 YP_001834951.1 225509 D 516950 CDS YP_001834952.1 182683205 6216976 225922..226416 1 NC_010582.1 located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance; 30S ribosomal protein S5 226416 rpsE 6216976 rpsE Streptococcus pneumoniae CGSP14 30S ribosomal protein S5 YP_001834952.1 225922 D 516950 CDS YP_001834953.1 182683206 6217561 226388..226612 1 NC_010582.1 L30 binds domain II of the 23S rRNA and the 5S rRNA; similar to eukaryotic protein L7; 50S ribosomal protein L30 226612 rpmD 6217561 rpmD Streptococcus pneumoniae CGSP14 50S ribosomal protein L30 YP_001834953.1 226388 D 516950 CDS YP_001834954.1 182683207 6217552 226757..227197 1 NC_010582.1 late assembly protein; 50S ribosomal protein L15 227197 rplO 6217552 rplO Streptococcus pneumoniae CGSP14 50S ribosomal protein L15 YP_001834954.1 226757 D 516950 CDS YP_001834955.1 182683208 6217536 227210..228520 1 NC_010582.1 forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase; preprotein translocase subunit SecY 228520 secY 6217536 secY Streptococcus pneumoniae CGSP14 preprotein translocase subunit SecY YP_001834955.1 227210 D 516950 CDS YP_001834956.1 182683209 6217518 228671..229309 1 NC_010582.1 essential enzyme that recycles AMP in active cells; converts ATP and AMP to two molecules of ADP; adenylate kinase 229309 adk 6217518 adk Streptococcus pneumoniae CGSP14 adenylate kinase YP_001834956.1 228671 D 516950 CDS YP_001834957.1 182683210 6217512 229372..229644 1 NC_010582.1 stimulates the activities of the other two initiation factors, IF-2 and IF-3; translation initiation factor IF-1 229644 infA 6217512 infA Streptococcus pneumoniae CGSP14 translation initiation factor IF-1 YP_001834957.1 229372 D 516950 CDS YP_001834958.1 182683211 6217505 229803..230168 1 NC_010582.1 located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA; 30S ribosomal protein S13 230168 rpsM 6217505 rpsM Streptococcus pneumoniae CGSP14 30S ribosomal protein S13 YP_001834958.1 229803 D 516950 CDS YP_001834959.1 182683212 6217503 230186..230569 1 NC_010582.1 located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3; 30S ribosomal protein S11 230569 rpsK 6217503 rpsK Streptococcus pneumoniae CGSP14 30S ribosomal protein S11 YP_001834959.1 230186 D 516950 CDS YP_001834960.1 182683213 6217492 230612..231547 1 NC_010582.1 catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme; DNA-directed RNA polymerase subunit alpha 231547 rpoA 6217492 rpoA Streptococcus pneumoniae CGSP14 DNA-directed RNA polymerase subunit alpha YP_001834960.1 230612 D 516950 CDS YP_001834961.1 182683214 6217491 231559..231945 1 NC_010582.1 is a component of the macrolide binding site in the peptidyl transferase center; 50S ribosomal protein L17 231945 rplQ 6217491 rplQ Streptococcus pneumoniae CGSP14 50S ribosomal protein L17 YP_001834961.1 231559 D 516950 CDS YP_001834962.1 182683215 6217122 232117..232476 1 NC_010582.1 ACT domain-containing protein; hypothetical protein 232476 6217122 SPCG_0245 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001834962.1 232117 D 516950 CDS YP_001834963.1 182683216 6218519 232523..233824 1 NC_010582.1 hypothetical protein 233824 6218519 SPCG_0246 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001834963.1 232523 D 516950 CDS YP_001834964.1 182683217 6217347 234011..234760 1 NC_010582.1 phosphoglycerate mutase family protein 234760 gpmB 6217347 gpmB Streptococcus pneumoniae CGSP14 phosphoglycerate mutase family protein YP_001834964.1 234011 D 516950 CDS YP_001834965.1 182683218 6217463 complement(234863..235897) 1 NC_010582.1 iron ABC transporter permease 235897 6217463 SPCG_0248 Streptococcus pneumoniae CGSP14 iron ABC transporter permease YP_001834965.1 234863 R 516950 CDS YP_001834966.1 182683219 6217442 complement(235882..236418) 1 NC_010582.1 iron ABC transporter permease 236418 6217442 SPCG_0250 Streptococcus pneumoniae CGSP14 iron ABC transporter permease YP_001834966.1 235882 R 516950 CDS YP_001834967.1 182683221 6217693 complement(236393..236485) 1 NC_010582.1 hypothetical protein 236485 6217693 SPCG_0249 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001834967.1 236393 R 516950 CDS YP_001834968.1 182683220 6217419 236462..236560 1 NC_010582.1 hypothetical protein 236560 6217419 SPCG_0251 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001834968.1 236462 D 516950 CDS YP_001834969.1 182683222 6217426 complement(236498..236902) 1 NC_010582.1 hypothetical protein 236902 6217426 SPCG_0252 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001834969.1 236498 R 516950 CDS YP_001834970.1 182683223 6217414 complement(236930..237526) 1 NC_010582.1 hypothetical protein 237526 6217414 SPCG_0253 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001834970.1 236930 R 516950 CDS YP_001834971.1 182683224 6217399 complement(237601..237969) 1 NC_010582.1 hypothetical protein 237969 6217399 SPCG_0254 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001834971.1 237601 R 516950 CDS YP_001834972.1 182683225 6217390 complement(238114..238707) 1 NC_010582.1 hypothetical protein 238707 6217390 SPCG_0255 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001834972.1 238114 R 516950 CDS YP_001834973.1 182683226 6217387 complement(239211..239987) 1 NC_010582.1 pyruvate formate-lyase-activating enzyme 239987 pflE 6217387 pflE Streptococcus pneumoniae CGSP14 pyruvate formate-lyase-activating enzyme YP_001834973.1 239211 R 516950 CDS YP_001834974.1 182683227 6217764 240061..240855 1 NC_010582.1 DeoR family transcriptional regulator 240855 deoR 6217764 deoR Streptococcus pneumoniae CGSP14 DeoR family transcriptional regulator YP_001834974.1 240061 D 516950 CDS YP_001834975.1 182683228 6217450 240868..241848 1 NC_010582.1 transcriptional regulator 241848 6217450 SPCG_0258 Streptococcus pneumoniae CGSP14 transcriptional regulator YP_001834975.1 240868 D 516950 CDS YP_001834976.1 182683229 6217216 242043..242363 1 NC_010582.1 PTS system transporter subunit IIA 242363 6217216 SPCG_0259 Streptococcus pneumoniae CGSP14 PTS system transporter subunit IIA YP_001834976.1 242043 D 516950 CDS YP_001834977.1 182683230 6217366 242409..242717 1 NC_010582.1 PTS system transporter subunit IIB 242717 6217366 SPCG_0260 Streptococcus pneumoniae CGSP14 PTS system transporter subunit IIB YP_001834977.1 242409 D 516950 CDS YP_001834978.1 182683231 6217362 242710..244032 1 NC_010582.1 PTS system transporter subunit IIC 244032 6217362 SPCG_0261 Streptococcus pneumoniae CGSP14 PTS system transporter subunit IIC YP_001834978.1 242710 D 516950 CDS YP_001834979.1 182683232 6217358 244174..246621 1 NC_010582.1 formate acetyltransferase 246621 pflF 6217358 pflF Streptococcus pneumoniae CGSP14 formate acetyltransferase YP_001834979.1 244174 D 516950 CDS YP_001834980.1 182683233 6217354 246640..247308 1 NC_010582.1 similar to transaldolase from Escherichia coli; many organisms have multiple copies; fructose-6-phosphate aldolase 247308 talC 6217354 talC Streptococcus pneumoniae CGSP14 fructose-6-phosphate aldolase YP_001834980.1 246640 D 516950 CDS YP_001834981.1 182683234 6217349 247326..248414 1 NC_010582.1 forms dimers and octamers; involved in conversion of glycerol to dihydroxy-acetone; glycerol dehydrogenase 248414 gldA 6217349 gldA Streptococcus pneumoniae CGSP14 glycerol dehydrogenase YP_001834981.1 247326 D 516950 CDS YP_001834982.1 182683235 6217345 248869..251370 1 NC_010582.1 leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase; leucyl-tRNA synthetase 251370 leuS 6217345 leuS Streptococcus pneumoniae CGSP14 leucyl-tRNA synthetase YP_001834982.1 248869 D 516950 CDS YP_001834983.1 182683236 6217344 251565..252260 1 NC_010582.1 acetyltransferase 252260 6217344 SPCG_0266 Streptococcus pneumoniae CGSP14 acetyltransferase YP_001834983.1 251565 D 516950 CDS YP_001834984.1 182683237 6217337 252272..252688 1 NC_010582.1 acetyltransferase 252688 6217337 SPCG_0267 Streptococcus pneumoniae CGSP14 acetyltransferase YP_001834984.1 252272 D 516950 CDS YP_001834985.1 182683238 6217332 complement(253503..253595) 1 NC_010582.1 hypothetical protein 253595 6217332 SPCG_0268 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001834985.1 253503 R 516950 CDS YP_001834986.1 182683239 6217780 253729..254727 1 NC_010582.1 promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration; Holliday junction DNA helicase RuvB 254727 ruvB 6217780 ruvB Streptococcus pneumoniae CGSP14 Holliday junction DNA helicase RuvB YP_001834986.1 253729 D 516950 CDS YP_001834987.1 182683240 6217328 254693..255280 1 NC_010582.1 hypothetical protein 255280 6217328 SPCG_0270 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001834987.1 254693 D 516950 CDS YP_001834988.1 182683241 6217375 255493..256269 1 NC_010582.1 catalyzes the formation of undecaprenyl pyrophosphate from isopentenyl pyrophosphate; undecaprenyl pyrophosphate synthase 256269 uppS 6217375 uppS Streptococcus pneumoniae CGSP14 undecaprenyl pyrophosphate synthase YP_001834988.1 255493 D 516950 CDS YP_001834989.1 182683242 6217752 256278..257081 1 NC_010582.1 phosphatidate cytidylyltransferase 257081 cdsA 6217752 cdsA Streptococcus pneumoniae CGSP14 phosphatidate cytidylyltransferase YP_001834989.1 256278 D 516950 CDS YP_001834990.1 182683243 6216798 257103..258362 1 NC_010582.1 eep protein 258362 eep 6216798 eep Streptococcus pneumoniae CGSP14 eep protein YP_001834990.1 257103 D 516950 CDS YP_001834991.1 182683244 6218199 258375..260228 1 NC_010582.1 catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro); prolyl-tRNA synthetase 260228 proS 6218199 proS Streptococcus pneumoniae CGSP14 prolyl-tRNA synthetase YP_001834991.1 258375 D 516950 CDS YP_001834992.1 182683245 6217309 260327..261706 1 NC_010582.1 glycosyl hydrolase family protein 261706 6217309 SPCG_0275 Streptococcus pneumoniae CGSP14 glycosyl hydrolase family protein YP_001834992.1 260327 D 516950 CDS YP_001834993.1 182683246 6217306 261899..263707 1 NC_010582.1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source; glucosamine--fructose-6-phosphate aminotransferase 263707 glmS 6217306 glmS Streptococcus pneumoniae CGSP14 glucosamine--fructose-6-phosphate aminotransferase YP_001834993.1 261899 D 516950 CDS YP_001834994.1 182683247 6217301 263826..264875 1 NC_010582.1 oxidoreductase 264875 6217301 SPCG_0277 Streptococcus pneumoniae CGSP14 oxidoreductase YP_001834994.1 263826 D 516950 CDS YP_001834995.1 182683248 6217283 complement(264975..268772) 1 NC_010582.1 alkaline amylopullulanase 268772 6217283 SPCG_0278 Streptococcus pneumoniae CGSP14 alkaline amylopullulanase YP_001834995.1 264975 R 516950 CDS YP_001834996.1 182683249 6217321 268849..270405 1 NC_010582.1 IS1380-Spn1 transposase 270405 6217321 SPCG_0279 Streptococcus pneumoniae CGSP14 IS1380-Spn1 transposase YP_001834996.1 268849 D 516950 CDS YP_001834997.1 182683250 6217268 270667..270762 1 NC_010582.1 hypothetical protein 270762 6217268 SPCG_0280 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001834997.1 270667 D 516950 CDS YP_001834998.1 182683251 6217266 270818..270910 1 NC_010582.1 hypothetical protein 270910 6217266 SPCG_0281 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001834998.1 270818 D 516950 CDS YP_001834999.1 182683252 6217483 270897..271310 1 NC_010582.1 interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance; 30S ribosomal protein S12 271310 rpsL 6217483 rpsL Streptococcus pneumoniae CGSP14 30S ribosomal protein S12 YP_001834999.1 270897 D 516950 CDS YP_001835000.1 182683253 6216968 271330..271800 1 NC_010582.1 binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit; 30S ribosomal protein S7 271800 rpsG 6216968 rpsG Streptococcus pneumoniae CGSP14 30S ribosomal protein S7 YP_001835000.1 271330 D 516950 CDS YP_001835001.1 182683254 6216961 272225..274306 1 NC_010582.1 EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene; elongation factor G 274306 fusA 6216961 fusA Streptococcus pneumoniae CGSP14 elongation factor G YP_001835001.1 272225 D 516950 CDS YP_001835002.1 182683255 6217001 274410..278801 1 NC_010582.1 catalyzes DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time; required for leading strand synthesis; PolC exhibits 3' to 5' exonuclease activity; DNA polymerase III PolC 278801 polC 6217001 polC Streptococcus pneumoniae CGSP14 DNA polymerase III PolC YP_001835002.1 274410 D 516950 CDS YP_001835003.1 182683256 6216953 278903..279166 1 NC_010582.1 hypothetical protein 279166 6216953 SPCG_0286 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835003.1 278903 D 516950 CDS YP_001835004.1 182683257 6216951 279159..279437 1 NC_010582.1 hypothetical protein 279437 6216951 SPCG_0287 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835004.1 279159 D 516950 CDS YP_001835005.1 182683258 6216937 279458..279610 1 NC_010582.1 hypothetical protein 279610 6216937 SPCG_0288 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835005.1 279458 D 516950 CDS YP_001835006.1 182683259 6217073 279632..280873 1 NC_010582.1 aminopeptidase PepS 280873 pepS 6217073 pepS Streptococcus pneumoniae CGSP14 aminopeptidase PepS YP_001835006.1 279632 D 516950 CDS YP_001835007.1 182683260 6216927 280883..281113 1 NC_010582.1 hypothetical protein 281113 6216927 SPCG_0290 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835007.1 280883 D 516950 CDS YP_001835008.1 182683261 6217046 281369..282091 1 NC_010582.1 ribosomal small subunit pseudouridine synthase A 282091 rsuA 6217046 rsuA Streptococcus pneumoniae CGSP14 ribosomal small subunit pseudouridine synthase A YP_001835008.1 281369 D 516950 CDS YP_001835009.1 182683262 6216913 282308..283642 1 NC_010582.1 aminopeptidase C 283642 pepC 6216913 pepC Streptococcus pneumoniae CGSP14 aminopeptidase C YP_001835009.1 282308 D 516950 CDS YP_001835010.1 182683263 6216378 complement(283698..284609) 1 NC_010582.1 PTS system mannose-specific transporter subunit IID 284609 manN 6216378 manN Streptococcus pneumoniae CGSP14 PTS system mannose-specific transporter subunit IID YP_001835010.1 283698 R 516950 CDS YP_001835011.1 182683264 6216907 complement(284633..285436) 1 NC_010582.1 PTS system mannose-specific transporter subunit IIC 285436 manM 6216907 manM Streptococcus pneumoniae CGSP14 PTS system mannose-specific transporter subunit IIC YP_001835011.1 284633 R 516950 CDS YP_001835012.1 182683265 6216905 complement(285464..286462) 1 NC_010582.1 PTS system mannose-specific transporter subunit IIAB 286462 manL 6216905 manL Streptococcus pneumoniae CGSP14 PTS system mannose-specific transporter subunit IIAB YP_001835012.1 285464 R 516950 CDS YP_001835013.1 182683266 6217135 complement(286862..288469) 1 NC_010582.1 IS1380-Spn1 transposase 288469 6217135 SPCG_0296 Streptococcus pneumoniae CGSP14 IS1380-Spn1 transposase YP_001835013.1 286862 R 516950 CDS YP_001835014.1 182683267 6216867 complement(288396..289415) 1 NC_010582.1 similar to zinc-dependent eukaryotic ADH enzymes and distinct from fermentative ADHs; alcohol dehydrogenase 289415 adhP 6216867 adhP Streptococcus pneumoniae CGSP14 alcohol dehydrogenase YP_001835014.1 288396 R 516950 CDS YP_001835015.1 182683268 6216597 complement(289524..289670) 1 NC_010582.1 hypothetical protein 289670 6216597 SPCG_0298 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835015.1 289524 R 516950 CDS YP_001835016.1 182683269 6217163 complement(289754..290566) 1 NC_010582.1 Cof family protein 290566 6217163 SPCG_0299 Streptococcus pneumoniae CGSP14 Cof family protein YP_001835016.1 289754 R 516950 CDS YP_001835017.1 182683270 6216457 290702..292174 1 NC_010582.1 xanthine/uracil permease family protein 292174 6216457 SPCG_0300 Streptococcus pneumoniae CGSP14 xanthine/uracil permease family protein YP_001835017.1 290702 D 516950 CDS YP_001835018.1 182683271 6217250 292224..292934 1 NC_010582.1 hypothetical protein 292934 6217250 SPCG_0301 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835018.1 292224 D 516950 CDS YP_001835019.1 182683272 6217034 293028..294008 1 NC_010582.1 dihydropteroate synthase 294008 sulA 6217034 sulA Streptococcus pneumoniae CGSP14 dihydropteroate synthase YP_001835019.1 293028 D 516950 CDS YP_001835020.1 182683273 6216889 294010..295332 1 NC_010582.1 dihydrofolate synthetase 295332 sulB 6216889 sulB Streptococcus pneumoniae CGSP14 dihydrofolate synthetase YP_001835020.1 294010 D 516950 CDS YP_001835021.1 182683274 6217486 295313..295867 1 NC_010582.1 involved in the first step of tetrahydrofolate biosynthesis; catalyzes the formation of formate and 2-amino-4-hydroxy-6-(erythro-1,2, 3-trihydroxypropyl)dihydropteridine triphosphate from GTP and water; forms a homopolymer; GTP cyclohydrolase I 295867 folE 6217486 folE Streptococcus pneumoniae CGSP14 GTP cyclohydrolase I YP_001835021.1 295313 D 516950 CDS YP_001835022.1 182683275 6216327 295910..296722 1 NC_010582.1 bifunctional folate synthesis protein 296722 sulD 6216327 sulD Streptococcus pneumoniae CGSP14 bifunctional folate synthesis protein YP_001835022.1 295910 D 516950 CDS YP_001835023.1 182683276 6216811 complement(296767..297138) 1 NC_010582.1 hypothetical protein 297138 6216811 SPCG_0306 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835023.1 296767 R 516950 CDS YP_001835024.1 182683277 6217159 complement(297128..297232) 1 NC_010582.1 hypothetical protein 297232 6217159 SPCG_0307 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835024.1 297128 R 516950 CDS YP_001835025.1 182683278 6216807 297441..297887 1 NC_010582.1 in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit; 50S ribosomal protein L13 297887 rplM 6216807 rplM Streptococcus pneumoniae CGSP14 50S ribosomal protein L13 YP_001835025.1 297441 D 516950 CDS YP_001835026.1 182683279 6216801 297907..298299 1 NC_010582.1 forms a direct contact with the tRNA during translation; 30S ribosomal protein S9 298299 rpsI 6216801 rpsI Streptococcus pneumoniae CGSP14 30S ribosomal protein S9 YP_001835026.1 297907 D 516950 CDS YP_001835027.1 182683280 6217313 298767..298937 1 NC_010582.1 hypothetical protein 298937 6217313 SPCG_0310 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835027.1 298767 D 516950 CDS YP_001835028.1 182683281 6216788 299013..299351 1 NC_010582.1 hypothetical protein 299351 6216788 SPCG_0311 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835028.1 299013 D 516950 CDS YP_001835029.1 182683282 6216785 299499..300977 1 NC_010582.1 converts 6-phospho-beta-D-glucosyl-(1,4)-D-glucose to glucose and glucose 6-phosphate; required for cellobiose uptake and metabolism; 6-phospho-beta-glucosidase 300977 celA 6216785 celA Streptococcus pneumoniae CGSP14 6-phospho-beta-glucosidase YP_001835029.1 299499 D 516950 CDS YP_001835030.1 182683283 6216783 301029..301268 1 NC_010582.1 hypothetical protein 301268 6216783 SPCG_0313 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835030.1 301029 D 516950 CDS YP_001835031.1 182683284 6216781 301371..301712 1 NC_010582.1 required for cellobiose uptake and metabolism; PTS system cellobiose transporter subunit IIB 301712 celB 6216781 celB Streptococcus pneumoniae CGSP14 PTS system cellobiose transporter subunit IIB YP_001835031.1 301371 D 516950 CDS YP_001835032.1 182683285 6216779 301830..303809 1 NC_010582.1 PTS system transporter subunit IIB 303809 6216779 SPCG_0315 Streptococcus pneumoniae CGSP14 PTS system transporter subunit IIB YP_001835032.1 301830 D 516950 CDS YP_001835033.1 182683286 6216777 303819..304133 1 NC_010582.1 required for cellobiose uptake and metabolism; cellobiose phosphotransferase system IIA component 304133 celC 6216777 celC Streptococcus pneumoniae CGSP14 cellobiose phosphotransferase system IIA component YP_001835033.1 303819 D 516950 CDS YP_001835034.1 182683287 6216775 304164..304670 1 NC_010582.1 hypothetical protein 304670 6216775 SPCG_0317 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835034.1 304164 D 516950 CDS YP_001835035.1 182683288 6216764 304750..306096 1 NC_010582.1 required for cellobiose uptake and metabolism; cellobiose phosphotransferase system IIC component 306096 celD 6216764 celD Streptococcus pneumoniae CGSP14 cellobiose phosphotransferase system IIC component YP_001835035.1 304750 D 516950 CDS YP_001835036.1 182683289 6216618 306477..306653 1 NC_010582.1 hypothetical protein 306653 6216618 SPCG_0319 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835036.1 306477 D 516950 CDS YP_001835037.1 182683290 6217198 307055..309268 1 NC_010582.1 glycosyl hydrolase family protein 309268 6217198 SPCG_0320 Streptococcus pneumoniae CGSP14 glycosyl hydrolase family protein YP_001835037.1 307055 D 516950 CDS YP_001835038.1 182683291 6217398 complement(309490..309966) 1 NC_010582.1 glutathione peroxidase 309966 basA 6217398 basA Streptococcus pneumoniae CGSP14 glutathione peroxidase YP_001835038.1 309490 R 516950 CDS YP_001835039.1 182683292 6216762 310156..313392 1 NC_010582.1 hyaluronidase 313392 6216762 SPCG_0322 Streptococcus pneumoniae CGSP14 hyaluronidase YP_001835039.1 310156 D 516950 CDS YP_001835040.1 182683293 6216753 complement(314536..315165) 1 NC_010582.1 catalyzes the formation of pyruvate and glyoxylate from 4-hydroxy-2-oxoglutarate; or pyruvate and D-glyceraldehyde 3-phosphate from 2-dehydro-3-deoxy-D-glyconate 6-phosphate; keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase 315165 kdgA 6216753 kdgA Streptococcus pneumoniae CGSP14 keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase YP_001835040.1 314536 R 516950 CDS YP_001835041.1 182683294 6216745 complement(315175..316176) 1 NC_010582.1 carbohydrate kinase 316176 6216745 SPCG_0324 Streptococcus pneumoniae CGSP14 carbohydrate kinase YP_001835041.1 315175 R 516950 CDS YP_001835042.1 182683295 6216739 complement(316207..316848) 1 NC_010582.1 hypothetical protein 316848 6216739 SPCG_0325 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835042.1 316207 R 516950 CDS YP_001835043.1 182683296 6218019 complement(316867..317682) 1 NC_010582.1 Involved in the nonphosphorylative, ketogenic oxidation of glucose and oxidizes gluconate to 5-ketogluconate; gluconate 5-dehydrogenase 317682 gno 6218019 gno Streptococcus pneumoniae CGSP14 gluconate 5-dehydrogenase YP_001835043.1 316867 R 516950 CDS YP_001835044.1 182683297 6216817 317954..318388 1 NC_010582.1 PTS system transporter subunit IIA 318388 6216817 SPCG_0327 Streptococcus pneumoniae CGSP14 PTS system transporter subunit IIA YP_001835044.1 317954 D 516950 CDS YP_001835045.1 182683298 6217199 318400..319590 1 NC_010582.1 glucuronyl hydrolase 319590 6217199 SPCG_0328 Streptococcus pneumoniae CGSP14 glucuronyl hydrolase YP_001835045.1 318400 D 516950 CDS YP_001835046.1 182683299 6217196 319601..320092 1 NC_010582.1 PTS system transporter subunit IIB 320092 6217196 SPCG_0329 Streptococcus pneumoniae CGSP14 PTS system transporter subunit IIB YP_001835046.1 319601 D 516950 CDS YP_001835047.1 182683300 6217041 320107..320886 1 NC_010582.1 PTS system transporter subunit IIC 320886 6217041 SPCG_0330 Streptococcus pneumoniae CGSP14 PTS system transporter subunit IIC YP_001835047.1 320107 D 516950 CDS YP_001835048.1 182683301 6216727 320873..321691 1 NC_010582.1 PTS system transporter subunit IID 321691 6216727 SPCG_0331 Streptococcus pneumoniae CGSP14 PTS system transporter subunit IID YP_001835048.1 320873 D 516950 CDS YP_001835049.1 182683302 6216992 321691..321984 1 NC_010582.1 preprotein translocase subunit YajC 321984 6216992 SPCG_0332 Streptococcus pneumoniae CGSP14 preprotein translocase subunit YajC YP_001835049.1 321691 D 516950 CDS YP_001835050.1 182683303 6216909 322006..323907 1 NC_010582.1 hypothetical protein 323907 6216909 SPCG_0333 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835050.1 322006 D 516950 CDS YP_001835051.1 182683304 6216376 323901..324968 1 NC_010582.1 sugar binding transcriptional regulator RegR 324968 regR 6216376 regR Streptococcus pneumoniae CGSP14 sugar binding transcriptional regulator RegR YP_001835051.1 323901 D 516950 CDS YP_001835052.1 182683305 6216724 complement(325424..325666) 1 NC_010582.1 hypothetical protein 325666 6216724 SPCG_0335 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835052.1 325424 R 516950 CDS YP_001835053.1 182683306 6216723 complement(325682..325876) 1 NC_010582.1 transcriptional regulator 325876 yorfE 6216723 yorfE Streptococcus pneumoniae CGSP14 transcriptional regulator YP_001835053.1 325682 R 516950 CDS YP_001835054.1 182683307 6216720 326042..326992 1 NC_010582.1 S-adenosyl-methyltransferase MraW 326992 mraW 6216720 mraW Streptococcus pneumoniae CGSP14 S-adenosyl-methyltransferase MraW YP_001835054.1 326042 D 516950 CDS YP_001835055.1 182683308 6216717 327004..327321 1 NC_010582.1 cell division protein FtsL 327321 ftsL 6216717 ftsL Streptococcus pneumoniae CGSP14 cell division protein FtsL YP_001835055.1 327004 D 516950 CDS YP_001835056.1 182683309 6216714 327325..329577 1 NC_010582.1 penicillin-binding protein 2X 329577 pbp2X 6216714 pbp2X Streptococcus pneumoniae CGSP14 penicillin-binding protein 2X YP_001835056.1 327325 D 516950 CDS YP_001835057.1 182683310 6216713 329579..330559 1 NC_010582.1 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; phospho-N-acetylmuramoyl-pentapeptide- transferase 330559 mraY 6216713 mraY Streptococcus pneumoniae CGSP14 phospho-N-acetylmuramoyl-pentapeptide- transferase YP_001835057.1 329579 D 516950 CDS YP_001835058.1 182683311 6216712 330699..330887 1 NC_010582.1 hypothetical protein 330887 6216712 SPCG_0341 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835058.1 330699 D 516950 CDS YP_001835059.1 182683312 6216699 331168..333273 1 NC_010582.1 ATP-dependent Clp protease, ATP-binding subunit 333273 clpL 6216699 clpL Streptococcus pneumoniae CGSP14 ATP-dependent Clp protease, ATP-binding subunit YP_001835059.1 331168 D 516950 CDS YP_001835060.1 182683313 6217141 complement(334126..334608) 1 NC_010582.1 catalyzes the hydrolysis of S-ribosylhomocysteine to homocysteine and autoinducer-2; S-ribosylhomocysteinase 334608 luxS 6217141 luxS Streptococcus pneumoniae CGSP14 S-ribosylhomocysteinase YP_001835060.1 334126 R 516950 CDS YP_001835061.1 182683314 6216621 complement(334703..336187) 1 NC_010582.1 hypothetical protein 336187 6216621 SPCG_0344 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835061.1 334703 R 516950 CDS YP_001835062.1 182683315 6216697 336340..337947 1 NC_010582.1 glucan 1,6-alpha-glucosidase 337947 dexB 6216697 dexB Streptococcus pneumoniae CGSP14 glucan 1,6-alpha-glucosidase YP_001835062.1 336340 D 516950 CDS YP_001835063.1 182683316 6216691 339007..340461 1 NC_010582.1 capsular polysaccharide biosynthesis protein Cps14A 340461 wzg 6216691 wzg Streptococcus pneumoniae CGSP14 capsular polysaccharide biosynthesis protein Cps14A YP_001835063.1 339007 D 516950 CDS YP_001835064.1 182683317 6216690 340463..341194 1 NC_010582.1 capsular polysaccharide biosynthesis protein Cps14B 341194 wzh 6216690 wzh Streptococcus pneumoniae CGSP14 capsular polysaccharide biosynthesis protein Cps14B YP_001835064.1 340463 D 516950 CDS YP_001835065.1 182683318 6216642 341203..341895 1 NC_010582.1 capsular polysaccharide biosynthesis protein Cps14C 341895 wzd 6216642 wzd Streptococcus pneumoniae CGSP14 capsular polysaccharide biosynthesis protein Cps14C YP_001835065.1 341203 D 516950 CDS YP_001835066.1 182683319 6217227 341905..342588 1 NC_010582.1 capsular polysaccharide biosynthesis protein Cps14D 342588 wze 6217227 wze Streptococcus pneumoniae CGSP14 capsular polysaccharide biosynthesis protein Cps14D YP_001835066.1 341905 D 516950 CDS YP_001835067.1 182683320 6217768 342604..343971 1 NC_010582.1 glucosyl-1-phosphate transferase 343971 wchA 6217768 wchA Streptococcus pneumoniae CGSP14 glucosyl-1-phosphate transferase YP_001835067.1 342604 D 516950 CDS YP_001835068.1 182683321 6216682 343975..344424 1 NC_010582.1 glycosyltransferase activity enhancer 344424 wchJ 6216682 wchJ Streptococcus pneumoniae CGSP14 glycosyltransferase activity enhancer YP_001835068.1 343975 D 516950 CDS YP_001835069.1 182683322 6216681 344424..344927 1 NC_010582.1 ss-1,4-galactosyltransferase 344927 wchK 6216681 wchK Streptococcus pneumoniae CGSP14 ss-1,4-galactosyltransferase YP_001835069.1 344424 D 516950 CDS YP_001835070.1 182683323 6216677 344917..346089 1 NC_010582.1 polysaccharide polymerase 346089 wzy 6216677 wzy Streptococcus pneumoniae CGSP14 polysaccharide polymerase YP_001835070.1 344917 D 516950 CDS YP_001835071.1 182683324 6217171 346086..347105 1 NC_010582.1 ss-1,3-N-acetylglucosaminyltransferase 347105 wchL 6217171 wchL Streptococcus pneumoniae CGSP14 ss-1,3-N-acetylglucosaminyltransferase YP_001835071.1 346086 D 516950 CDS YP_001835072.1 182683325 6217132 347075..348076 1 NC_010582.1 ss-1,4-galactosyltransferase 348076 wchM 6217132 wchM Streptococcus pneumoniae CGSP14 ss-1,4-galactosyltransferase YP_001835072.1 347075 D 516950 CDS YP_001835073.1 182683326 6217352 348144..349013 1 NC_010582.1 capsular polysaccharide synthesis protein 349013 wchN 6217352 wchN Streptococcus pneumoniae CGSP14 capsular polysaccharide synthesis protein YP_001835073.1 348144 D 516950 CDS YP_001835074.1 182683327 6217097 348997..350469 1 NC_010582.1 transporter 350469 wzx 6217097 wzx Streptococcus pneumoniae CGSP14 transporter YP_001835074.1 348997 D 516950 CDS YP_001835075.1 182683328 6217703 350621..350713 1 NC_010582.1 hypothetical protein 350713 6217703 SPCG_0358 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835075.1 350621 D 516950 CDS YP_001835076.1 182683329 6217229 350730..351047 1 NC_010582.1 hypothetical protein 351047 6217229 SPCG_0359 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835076.1 350730 D 516950 CDS YP_001835077.1 182683330 6216940 351407..353770 1 NC_010582.1 surface anchored protein 353770 lrp 6216940 lrp Streptococcus pneumoniae CGSP14 surface anchored protein YP_001835077.1 351407 D 516950 CDS YP_001835078.1 182683331 6216379 complement(353925..354452) 1 NC_010582.1 degenerate transposase 354452 6216379 SPCG_0361 Streptococcus pneumoniae CGSP14 degenerate transposase YP_001835078.1 353925 R 516950 CDS YP_001835079.1 182683332 6217863 complement(354733..355251) 1 NC_010582.1 degenerate transposase 355251 6217863 SPCG_0362 Streptococcus pneumoniae CGSP14 degenerate transposase YP_001835079.1 354733 R 516950 CDS YP_001835080.1 182683333 6216966 355487..357472 1 NC_010582.1 oligopeptide ABC transporter oligopeptide-binding protein AliA 357472 aliA 6216966 aliA Streptococcus pneumoniae CGSP14 oligopeptide ABC transporter oligopeptide-binding protein AliA YP_001835080.1 355487 D 516950 CDS YP_001835081.1 182683334 6217035 357773..363076 1 NC_010582.1 cell wall surface anchor family protein 363076 6217035 SPCG_0364 Streptococcus pneumoniae CGSP14 cell wall surface anchor family protein YP_001835081.1 357773 D 516950 CDS YP_001835082.1 182683335 6217308 complement(363243..365402) 1 NC_010582.1 penicillin-binding protein 1A 365402 pbp1A 6217308 pbp1A Streptococcus pneumoniae CGSP14 penicillin-binding protein 1A YP_001835082.1 363243 R 516950 CDS YP_001835083.1 182683337 6217825 complement(365399..365995) 1 NC_010582.1 functions in homologous recombination, DNA repair, and chromosome segregation; binds preferentially to three- and four-stranded DNA intermediates; introduces specific nick sites in four-stranded DNA substrates; functions similarly to Escherichia coli RuvC; Holliday junction-specific endonuclease 365995 recU 6217825 recU Streptococcus pneumoniae CGSP14 Holliday junction-specific endonuclease YP_001835083.1 365399 R 516950 CDS YP_001835084.1 182683336 6217843 365978..366589 1 NC_010582.1 hypothetical protein 366589 6217843 SPCG_0367 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835084.1 365978 D 516950 CDS YP_001835085.1 182683338 6217109 366647..367000 1 NC_010582.1 hypothetical protein 367000 6217109 SPCG_0368 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835085.1 366647 D 516950 CDS YP_001835086.1 182683339 6217595 367471..368643 1 NC_010582.1 hypothetical protein 368643 6217595 SPCG_0369 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835086.1 367471 D 516950 CDS YP_001835087.1 182683340 6216693 368656..370050 1 NC_010582.1 hypothetical protein 370050 6216693 SPCG_0370 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835087.1 368656 D 516950 CDS YP_001835088.1 182683341 6217714 370105..371550 1 NC_010582.1 catalyzes the formation of D-ribulose 5-phosphate from 6-phospho-D-gluconate; 6-phosphogluconate dehydrogenase 371550 gnd 6217714 gnd Streptococcus pneumoniae CGSP14 6-phosphogluconate dehydrogenase YP_001835088.1 370105 D 516950 CDS YP_001835089.1 182683342 6216962 371562..372251 1 NC_010582.1 DNA-binding response regulator 372251 csrR 6216962 csrR Streptococcus pneumoniae CGSP14 DNA-binding response regulator YP_001835089.1 371562 D 516950 CDS YP_001835090.1 182683343 6217319 372260..373348 1 NC_010582.1 choline binding protein J 373348 cbpJ 6217319 cbpJ Streptococcus pneumoniae CGSP14 choline binding protein J YP_001835090.1 372260 D 516950 CDS YP_001835091.1 182683344 6216760 complement(373466..374722) 1 NC_010582.1 hypothetical protein 374722 6216760 SPCG_0374 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835091.1 373466 R 516950 CDS YP_001835092.1 182683345 6217205 complement(374857..375327) 1 NC_010582.1 hypothetical protein 375327 6217205 SPCG_0375 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835092.1 374857 R 516950 CDS YP_001835093.1 182683346 6218251 376699..377577 1 NC_010582.1 mevalonate kinase 377577 mvk 6218251 mvk Streptococcus pneumoniae CGSP14 mevalonate kinase YP_001835093.1 376699 D 516950 CDS YP_001835094.1 182683347 6217412 377559..378512 1 NC_010582.1 diphosphomevalonate decarboxylase 378512 mvd1 6217412 mvd1 Streptococcus pneumoniae CGSP14 diphosphomevalonate decarboxylase YP_001835094.1 377559 D 516950 CDS YP_001835095.1 182683348 6218153 378499..379506 1 NC_010582.1 phosphomevalonate kinase 379506 mvaK2 6218153 mvaK2 Streptococcus pneumoniae CGSP14 phosphomevalonate kinase YP_001835095.1 378499 D 516950 CDS YP_001835096.1 182683349 6217477 379490..380500 1 NC_010582.1 catalyzes the isomerization of isopentenyl pyrophosphate to dimethylallyl diphosphate; isopentenyl pyrophosphate isomerase 380500 fni 6217477 fni Streptococcus pneumoniae CGSP14 isopentenyl pyrophosphate isomerase YP_001835096.1 379490 D 516950 CDS YP_001835097.1 182683350 6218263 380577..381275 1 NC_010582.1 hypothetical protein 381275 6218263 SPCG_0380 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835097.1 380577 D 516950 CDS YP_001835098.1 182683351 6217705 381272..382267 1 NC_010582.1 sensor histidine kinase 382267 6217705 SPCG_0381 Streptococcus pneumoniae CGSP14 sensor histidine kinase YP_001835098.1 381272 D 516950 CDS YP_001835099.1 182683352 6217108 382281..382913 1 NC_010582.1 DNA-binding response regulator 382913 6217108 SPCG_0382 Streptococcus pneumoniae CGSP14 DNA-binding response regulator YP_001835099.1 382281 D 516950 CDS YP_001835100.1 182683353 6217922 382914..383156 1 NC_010582.1 hypothetical protein 383156 6217922 SPCG_0383 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835100.1 382914 D 516950 CDS YP_001835101.1 182683354 6217638 383138..383392 1 NC_010582.1 DNA alkylation repair enzyme, truncation 383392 6217638 SPCG_0384 Streptococcus pneumoniae CGSP14 DNA alkylation repair enzyme, truncation YP_001835101.1 383138 D 516950 CDS YP_001835102.1 182683355 6218063 383411..383683 1 NC_010582.1 DNA alkylation repair enzyme, truncation 383683 6218063 SPCG_0385 Streptococcus pneumoniae CGSP14 DNA alkylation repair enzyme, truncation YP_001835102.1 383411 D 516950 CDS YP_001835103.1 182683356 6218296 383833..384072 1 NC_010582.1 hypothetical protein 384072 6218296 SPCG_0386 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835103.1 383833 D 516950 CDS YP_001835104.1 182683357 6217428 384069..384974 1 NC_010582.1 choline binding protein G 384974 cbpG 6217428 cbpG Streptococcus pneumoniae CGSP14 choline binding protein G YP_001835104.1 384069 D 516950 CDS YP_001835105.1 182683358 6216467 384993..385418 1 NC_010582.1 hypothetical protein 385418 6216467 SPCG_0388 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835105.1 384993 D 516950 CDS YP_001835106.1 182683359 6218074 385536..386015 1 NC_010582.1 hypothetical protein 386015 6218074 SPCG_0389 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835106.1 385536 D 516950 CDS YP_001835107.1 182683360 6216684 complement(386143..386328) 1 NC_010582.1 degenerate transposase 386328 6216684 SPCG_0390 Streptococcus pneumoniae CGSP14 degenerate transposase YP_001835107.1 386143 R 516950 CDS YP_001835108.1 182683361 6216475 complement(386276..386506) 1 NC_010582.1 degenerate transposase 386506 6216475 SPCG_0391 Streptococcus pneumoniae CGSP14 degenerate transposase YP_001835108.1 386276 R 516950 CDS YP_001835109.1 182683362 6216446 complement(386568..386840) 1 NC_010582.1 degenerate transposase 386840 6216446 SPCG_0392 Streptococcus pneumoniae CGSP14 degenerate transposase YP_001835109.1 386568 R 516950 CDS YP_001835110.1 182683363 6217637 complement(387066..387341) 1 NC_010582.1 degenerate transposase 387341 6217637 SPCG_0393 Streptococcus pneumoniae CGSP14 degenerate transposase YP_001835110.1 387066 R 516950 CDS YP_001835111.1 182683364 6217017 387487..389256 1 NC_010582.1 PTS system mannitol-specific transporter subunit IIBC 389256 mtlA 6217017 mtlA Streptococcus pneumoniae CGSP14 PTS system mannitol-specific transporter subunit IIBC YP_001835111.1 387487 D 516950 CDS YP_001835112.1 182683365 6216606 389280..391235 1 NC_010582.1 transcriptional regulator 391235 6216606 SPCG_0395 Streptococcus pneumoniae CGSP14 transcriptional regulator YP_001835112.1 389280 D 516950 CDS YP_001835113.1 182683366 6218241 391237..391674 1 NC_010582.1 PTS system mannitol-specific transporter subunit IIA 391674 mtlF 6218241 mtlF Streptococcus pneumoniae CGSP14 PTS system mannitol-specific transporter subunit IIA YP_001835113.1 391237 D 516950 CDS YP_001835114.1 182683367 6217060 391736..392872 1 NC_010582.1 mannitol-1-phosphate 5-dehydrogenase 392872 mtlD 6217060 mtlD Streptococcus pneumoniae CGSP14 mannitol-1-phosphate 5-dehydrogenase YP_001835114.1 391736 D 516950 CDS YP_001835115.1 182683368 6218146 393088..393246 1 NC_010582.1 hypothetical protein 393246 6218146 SPCG_0398 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835115.1 393088 D 516950 CDS YP_001835116.1 182683369 6216639 393716..394999 1 NC_010582.1 Tig; RopA; peptidyl-prolyl cis/trans isomerase; promotes folding of newly synthesized proteins; binds ribosomal 50S subunit; forms a homodimer; trigger factor 394999 tig 6216639 tig Streptococcus pneumoniae CGSP14 trigger factor YP_001835116.1 393716 D 516950 CDS YP_001835117.1 182683370 6217954 complement(395047..397413) 1 NC_010582.1 helicase 397413 recD 6217954 recD Streptococcus pneumoniae CGSP14 helicase YP_001835117.1 395047 R 516950 CDS YP_001835118.1 182683371 6216774 complement(397647..398261) 1 NC_010582.1 signal peptidase I 398261 spi 6216774 spi Streptococcus pneumoniae CGSP14 signal peptidase I YP_001835118.1 397647 R 516950 CDS YP_001835119.1 182683372 6217850 complement(398273..399145) 1 NC_010582.1 An endonuclease that specifically degrades the RNA strand of RNA-DNA hybrids; ribonuclease HIII 399145 6217850 SPCG_0402 Streptococcus pneumoniae CGSP14 ribonuclease HIII YP_001835119.1 398273 R 516950 CDS YP_001835120.1 182683373 6218163 399223..399534 1 NC_010582.1 hypothetical protein 399534 6218163 SPCG_0403 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835120.1 399223 D 516950 CDS YP_001835121.1 182683374 6216654 399531..400079 1 NC_010582.1 hypothetical protein 400079 6216654 SPCG_0404 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835121.1 399531 D 516950 CDS YP_001835122.1 182683375 6216988 400183..402519 1 NC_010582.1 mutS2 family protein 402519 mutS2 6216988 mutS2 Streptococcus pneumoniae CGSP14 mutS2 family protein YP_001835122.1 400183 D 516950 CDS YP_001835123.1 182683376 6218174 complement(402640..402741) 1 NC_010582.1 hypothetical protein 402741 6218174 SPCG_0406 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835123.1 402640 R 516950 CDS YP_001835124.1 182683377 6217689 402862..404184 1 NC_010582.1 sodium:alanine symporter family protein 404184 dagA 6217689 dagA Streptococcus pneumoniae CGSP14 sodium:alanine symporter family protein YP_001835124.1 402862 D 516950 CDS YP_001835125.1 182683378 6216851 404402..404950 1 NC_010582.1 hypothetical protein 404950 mip 6216851 mip Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835125.1 404402 D 516950 CDS YP_001835126.1 182683379 6217631 405048..405959 1 NC_010582.1 exfoliative toxin 405959 shetA 6217631 shetA Streptococcus pneumoniae CGSP14 exfoliative toxin YP_001835126.1 405048 D 516950 CDS YP_001835127.1 182683380 6217357 complement(405984..407342) 1 NC_010582.1 catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; seryl-tRNA synthetase 407342 serS 6217357 serS Streptococcus pneumoniae CGSP14 seryl-tRNA synthetase YP_001835127.1 405984 R 516950 CDS YP_001835128.1 182683381 6216936 complement(407472..407843) 1 NC_010582.1 hypothetical protein 407843 6216936 SPCG_0411 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835128.1 407472 R 516950 CDS YP_001835129.1 182683382 6216539 complement(407846..409210) 1 NC_010582.1 catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP; lysine and threonine sensitive; aspartate kinase 409210 lysC 6216539 lysC Streptococcus pneumoniae CGSP14 aspartate kinase YP_001835129.1 407846 R 516950 CDS YP_001835130.1 182683383 6218155 409579..410349 1 NC_010582.1 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; enoyl-CoA hydratase 410349 phaB 6218155 phaB Streptococcus pneumoniae CGSP14 enoyl-CoA hydratase YP_001835130.1 409579 D 516950 CDS YP_001835131.1 182683384 6217367 410459..410893 1 NC_010582.1 MarR family transcriptional regulator 410893 6217367 SPCG_0414 Streptococcus pneumoniae CGSP14 MarR family transcriptional regulator YP_001835131.1 410459 D 516950 CDS YP_001835132.1 182683385 6218096 410893..411867 1 NC_010582.1 FabH; beta-ketoacyl-acyl carrier protein synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs; 3-oxoacyl-ACP synthase 411867 fabH 6218096 fabH Streptococcus pneumoniae CGSP14 3-oxoacyl-ACP synthase YP_001835132.1 410893 D 516950 CDS YP_001835133.1 182683386 6217180 411927..412151 1 NC_010582.1 carries the fatty acid chain in fatty acid biosynthesis; acyl carrier protein 412151 acpP 6217180 acpP Streptococcus pneumoniae CGSP14 acyl carrier protein YP_001835133.1 411927 D 516950 CDS YP_001835134.1 182683387 6217209 412270..413244 1 NC_010582.1 enoyl-(acyl-carrier-protein) reductase 413244 fabK 6217209 fabK Streptococcus pneumoniae CGSP14 enoyl-(acyl-carrier-protein) reductase YP_001835134.1 412270 D 516950 CDS YP_001835135.1 182683388 6217133 413237..414157 1 NC_010582.1 acyl-carrier-protein S-malonyltransferase 414157 fabD 6217133 fabD Streptococcus pneumoniae CGSP14 acyl-carrier-protein S-malonyltransferase YP_001835135.1 413237 D 516950 CDS YP_001835136.1 182683389 6217269 414191..414922 1 NC_010582.1 catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis; 3-ketoacyl-ACP reductase 414922 fabG 6217269 fabG Streptococcus pneumoniae CGSP14 3-ketoacyl-ACP reductase YP_001835136.1 414191 D 516950 CDS YP_001835137.1 182683390 6216943 414935..416179 1 NC_010582.1 FabF; beta-ketoacyl-ACP synthase II, KASII; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP; 3-oxoacyl-(acyl carrier protein) synthase II 416179 fabF 6216943 fabF Streptococcus pneumoniae CGSP14 3-oxoacyl-(acyl carrier protein) synthase II YP_001835137.1 414935 D 516950 CDS YP_001835138.1 182683391 6217036 416182..416667 1 NC_010582.1 composes the biotin carboxyl carrier protein subunit of the acetyl-CoA carboxylase complex, the enzyme that catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, which in turn controls the rate of fatty acid metabolism; acetyl-CoA carboxylase biotin carboxyl carrier protein subunit 416667 accB 6217036 accB Streptococcus pneumoniae CGSP14 acetyl-CoA carboxylase biotin carboxyl carrier protein subunit YP_001835138.1 416182 D 516950 CDS YP_001835139.1 182683392 6216612 416664..417086 1 NC_010582.1 in Pseudomonas aeruginosa this enzyme is a trimer of dimers; essential for membrane formation; performs third step of type II fatty acid biosynthesis; catalyzes dehydration of (3R)-hydroxyacyl-ACP to trans-2-acyl-ACP; (3R)-hydroxymyristoyl-ACP dehydratase 417086 fabZ 6216612 fabZ Streptococcus pneumoniae CGSP14 (3R)-hydroxymyristoyl-ACP dehydratase YP_001835139.1 416664 D 516950 CDS YP_001835140.1 182683393 6218068 417098..418465 1 NC_010582.1 an AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism; acetyl-CoA carboxylase biotin carboxylase subunit 418465 accC 6218068 accC Streptococcus pneumoniae CGSP14 acetyl-CoA carboxylase biotin carboxylase subunit YP_001835140.1 417098 D 516950 CDS YP_001835141.1 182683394 6218226 418502..419368 1 NC_010582.1 catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer of AccA2D2 subunits; acetyl-CoA carboxylase subunit beta 419368 accD 6218226 accD Streptococcus pneumoniae CGSP14 acetyl-CoA carboxylase subunit beta YP_001835141.1 418502 D 516950 CDS YP_001835142.1 182683395 6218112 419365..420132 1 NC_010582.1 catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer composed of two alpha (AccA) and two beta (AccD) subunits; one of the two catalytic subunits that can form the acetyl CoA carboxylase enzyme together with a carrier protein; these proteins present a shorter N-terminus; acetyl-CoA carboxylase subunit alpha 420132 accA 6218112 accA Streptococcus pneumoniae CGSP14 acetyl-CoA carboxylase subunit alpha YP_001835142.1 419365 D 516950 CDS YP_001835143.1 182683396 6217617 420329..420580 1 NC_010582.1 hypothetical protein 420580 6217617 SPCG_0426 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835143.1 420329 D 516950 CDS YP_001835144.1 182683397 6217317 complement(421370..421810) 1 NC_010582.1 Regulates rRNA biosynthesis by transcriptional antitermination; transcription antitermination protein NusB 421810 nusB 6217317 nusB Streptococcus pneumoniae CGSP14 transcription antitermination protein NusB YP_001835144.1 421370 R 516950 CDS YP_001835145.1 182683398 6218227 complement(421785..422174) 1 NC_010582.1 hypothetical protein 422174 6218227 SPCG_0428 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835145.1 421785 R 516950 CDS YP_001835146.1 182683399 6216852 complement(422196..422756) 1 NC_010582.1 Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA; elongation factor P 422756 efp 6216852 efp Streptococcus pneumoniae CGSP14 elongation factor P YP_001835146.1 422196 R 516950 CDS YP_001835147.1 182683400 6217339 complement(422885..424327) 1 NC_010582.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; aspartyl/glutamyl-tRNA amidotransferase subunit B 424327 gatB 6217339 gatB Streptococcus pneumoniae CGSP14 aspartyl/glutamyl-tRNA amidotransferase subunit B YP_001835147.1 422885 R 516950 CDS YP_001835148.1 182683401 6217087 complement(424327..425793) 1 NC_010582.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; aspartyl/glutamyl-tRNA amidotransferase subunit A 425793 gatA 6217087 gatA Streptococcus pneumoniae CGSP14 aspartyl/glutamyl-tRNA amidotransferase subunit A YP_001835148.1 424327 R 516950 CDS YP_001835149.1 182683402 6216571 complement(425793..426155) 1 NC_010582.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; some Mycoplasma proteins contain an N-terminal fusion to an unknown domain; aspartyl/glutamyl-tRNA amidotransferase subunit C 426155 gatC 6216571 gatC Streptococcus pneumoniae CGSP14 aspartyl/glutamyl-tRNA amidotransferase subunit C YP_001835149.1 425793 R 516950 CDS YP_001835150.1 182683403 6217000 426308..427852 1 NC_010582.1 stimulates the release of release factors 1 and 2 from the ribosome after hydrolysis of the ester bond in peptidyl-tRNA has occurred; GDP/GTP-binding protein; peptide chain release factor 3 427852 prfC 6217000 prfC Streptococcus pneumoniae CGSP14 peptide chain release factor 3 YP_001835150.1 426308 D 516950 CDS YP_001835151.1 182683404 6216929 428107..428304 1 NC_010582.1 hypothetical protein 428304 6216929 SPCG_0434 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835151.1 428107 D 516950 CDS YP_001835152.1 182683405 6217746 428415..428591 1 NC_010582.1 hypothetical protein 428591 6217746 SPCG_0435 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835152.1 428415 D 516950 CDS YP_001835153.1 182683406 6217066 428707..428895 1 NC_010582.1 required for 70S ribosome assembly; 50S ribosomal protein L28 428895 rpmB 6217066 rpmB Streptococcus pneumoniae CGSP14 50S ribosomal protein L28 YP_001835153.1 428707 D 516950 CDS YP_001835154.1 182683407 6216877 429052..429417 1 NC_010582.1 hypothetical protein 429417 asp23 6216877 asp23 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835154.1 429052 D 516950 CDS YP_001835155.1 182683408 6217432 429420..431087 1 NC_010582.1 hypothetical protein 431087 6217432 SPCG_0438 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835155.1 429420 D 516950 CDS YP_001835156.1 182683409 6217905 431288..432988 1 NC_010582.1 catalyzes the formation of 2-acetolactate from pyruvate; also known as acetolactate synthase large subunit; acetolactate synthase catalytic subunit 432988 ilvB 6217905 ilvB Streptococcus pneumoniae CGSP14 acetolactate synthase catalytic subunit YP_001835156.1 431288 D 516950 CDS YP_001835157.1 182683410 6218172 432957..433457 1 NC_010582.1 with IlvI catalyzes the formation of 2-acetolactate from pyruvate, the small subunit is required for full activity and valine sensitivity; E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates, valine sensitivity and affinity for cofactors; also known as acetolactate synthase 3 small subunit; acetolactate synthase 3 regulatory subunit 433457 ilvH 6218172 ilvH Streptococcus pneumoniae CGSP14 acetolactate synthase 3 regulatory subunit YP_001835157.1 432957 D 516950 CDS YP_001835158.1 182683411 6218374 433523..434545 1 NC_010582.1 catalyzes the formation of (R)-2,3-dihydroxy-3-methylbutanoate from (S)-2-hydroxy-2-methyl-3-oxobutanoate in valine and isoleucine biosynthesis; ketol-acid reductoisomerase 434545 ilvC 6218374 ilvC Streptococcus pneumoniae CGSP14 ketol-acid reductoisomerase YP_001835158.1 433523 D 516950 CDS YP_001835159.1 182683412 6218248 434622..434888 1 NC_010582.1 hypothetical protein 434888 6218248 SPCG_0442 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835159.1 434622 D 516950 CDS YP_001835160.1 182683413 6216472 435126..435482 1 NC_010582.1 hypothetical protein 435482 6216472 SPCG_0443 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835160.1 435126 D 516950 CDS YP_001835161.1 182683414 6217042 435532..436782 1 NC_010582.1 catalyzes the formation of 2-oxobutanoate from L-threonine; biosynthetic; threonine dehydratase 436782 ilvA 6217042 ilvA Streptococcus pneumoniae CGSP14 threonine dehydratase YP_001835161.1 435532 D 516950 CDS YP_001835162.1 182683415 6216816 436924..437112 1 NC_010582.1 hypothetical protein 437112 6216816 SPCG_0445 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835162.1 436924 D 516950 CDS YP_001835163.1 182683416 6217178 437666..437881 1 NC_010582.1 hypothetical protein 437881 6217178 SPCG_0446 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835163.1 437666 D 516950 CDS YP_001835164.1 182683417 6218304 complement(437990..438730) 1 NC_010582.1 amino acid ABC transporter ATP-binding protein 438730 glnQ 6218304 glnQ Streptococcus pneumoniae CGSP14 amino acid ABC transporter ATP-binding protein YP_001835164.1 437990 R 516950 CDS YP_001835165.1 182683418 6216708 complement(438730..440295) 1 NC_010582.1 amino acid ABC transporter amino acid-binding protein/permease 440295 glnH 6216708 glnH Streptococcus pneumoniae CGSP14 amino acid ABC transporter amino acid-binding protein/permease YP_001835165.1 438730 R 516950 CDS YP_001835166.1 182683419 6218060 440430..442322 1 NC_010582.1 hypothetical protein 442322 6218060 SPCG_0449 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835166.1 440430 D 516950 CDS YP_001835167.1 182683420 6216897 complement(442319..442489) 1 NC_010582.1 hypothetical protein 442489 6216897 SPCG_0450 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835167.1 442319 R 516950 CDS YP_001835168.1 182683421 6217297 complement(442701..443171) 1 NC_010582.1 degenerate transposase 443171 6217297 SPCG_0451 Streptococcus pneumoniae CGSP14 degenerate transposase YP_001835168.1 442701 R 516950 CDS YP_001835169.1 182683422 6216924 443747..444592 1 NC_010582.1 BacA; phosphatase activity in Escherichia coli not kinase; involved in bacitracin resistance as bacitracin supposedly sequesters undecaprenyl disphosphate which reduces the pool of lipid carrier available to the cell; undecaprenyl pyrophosphate phosphatase 444592 6216924 SPCG_0452 Streptococcus pneumoniae CGSP14 undecaprenyl pyrophosphate phosphatase YP_001835169.1 443747 D 516950 CDS YP_001835170.1 182683423 6218302 complement(444631..445275) 1 NC_010582.1 degenerate transposase 445275 6218302 SPCG_0453 Streptococcus pneumoniae CGSP14 degenerate transposase YP_001835170.1 444631 R 516950 CDS YP_001835171.1 182683424 6216945 complement(445272..445922) 1 NC_010582.1 degenerate transposase 445922 6216945 SPCG_0454 Streptococcus pneumoniae CGSP14 degenerate transposase YP_001835171.1 445272 R 516950 CDS YP_001835172.1 182683425 6217316 complement(446159..447286) 1 NC_010582.1 involved in translesion DNA polymerization with beta clamp of polymerase III; belongs to Y family of polymerases; does not contain proofreading function; DNA polymerase IV 447286 dinP 6217316 dinP Streptococcus pneumoniae CGSP14 DNA polymerase IV YP_001835172.1 446159 R 516950 CDS YP_001835173.1 182683426 6217550 447568..449892 1 NC_010582.1 formate acetyltransferase 449892 pfl 6217550 pfl Streptococcus pneumoniae CGSP14 formate acetyltransferase YP_001835173.1 447568 D 516950 CDS YP_001835174.1 182683427 6218049 complement(450260..450607) 1 NC_010582.1 hypothetical protein 450607 6218049 SPCG_0457 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835174.1 450260 R 516950 CDS YP_001835175.1 182683428 6217212 complement(450805..451089) 1 NC_010582.1 hypothetical protein 451089 6217212 SPCG_0458 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835175.1 450805 R 516950 CDS YP_001835176.1 182683429 6217881 452664..452888 1 NC_010582.1 PTS system lactose-specific transporter subunit IIBC truncated 452888 6217881 SPCG_0459 Streptococcus pneumoniae CGSP14 PTS system lactose-specific transporter subunit IIBC truncated YP_001835176.1 452664 D 516950 CDS YP_001835177.1 182683430 6216479 complement(453013..454452) 1 NC_010582.1 Trk family potassium uptake protein 454452 trkH 6216479 trkH Streptococcus pneumoniae CGSP14 Trk family potassium uptake protein YP_001835177.1 453013 R 516950 CDS YP_001835178.1 182683431 6216541 complement(454456..455805) 1 NC_010582.1 involved in potassium uptake; found to be peripherally associated with the inner membrane in Escherichia coli; contains an NAD-binding domain; potassium transporter peripheral membrane protein 455805 trkA 6216541 trkA Streptococcus pneumoniae CGSP14 potassium transporter peripheral membrane protein YP_001835178.1 454456 R 516950 CDS YP_001835179.1 182683432 6216385 455966..456841 1 NC_010582.1 hypothetical protein 456841 6216385 SPCG_0462 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835179.1 455966 D 516950 CDS YP_001835180.1 182683433 6216725 456856..457404 1 NC_010582.1 hypothetical protein 457404 6216725 SPCG_0463 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835180.1 456856 D 516950 CDS YP_001835181.1 182683434 6217465 457411..457668 1 NC_010582.1 hypothetical protein 457668 6217465 SPCG_0464 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835181.1 457411 D 516950 CDS YP_001835182.1 182683435 6218344 457770..459452 1 NC_010582.1 ABC transporter ATP-binding protein 459452 6218344 SPCG_0465 Streptococcus pneumoniae CGSP14 ABC transporter ATP-binding protein YP_001835182.1 457770 D 516950 CDS YP_001835183.1 182683436 6217980 459437..460267 1 NC_010582.1 hypothetical protein 460267 6217980 SPCG_0466 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835183.1 459437 D 516950 CDS YP_001835184.1 182683437 6216721 460421..460963 1 NC_010582.1 RNA methyltransferase 460963 cspR 6216721 cspR Streptococcus pneumoniae CGSP14 RNA methyltransferase YP_001835184.1 460421 D 516950 CDS YP_001835185.1 182683438 6217033 461401..461979 1 NC_010582.1 hypothetical protein 461979 6217033 SPCG_0468 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835185.1 461401 D 516950 CDS YP_001835186.1 182683439 6216609 461969..462619 1 NC_010582.1 PAP2 family protein 462619 6216609 SPCG_0469 Streptococcus pneumoniae CGSP14 PAP2 family protein YP_001835186.1 461969 D 516950 CDS YP_001835187.1 182683440 6217149 462647..463036 1 NC_010582.1 hypothetical protein 463036 6217149 SPCG_0470 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835187.1 462647 D 516950 CDS YP_001835188.1 182683441 6216821 463041..463490 1 NC_010582.1 hypothetical protein 463490 6216821 SPCG_0471 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835188.1 463041 D 516950 CDS YP_001835189.1 182683442 6216895 463603..464205 1 NC_010582.1 participates in both the initiation and recycling phases of transcription; in the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling; DNA-directed RNA polymerase subunit delta 464205 rpoE 6216895 rpoE Streptococcus pneumoniae CGSP14 DNA-directed RNA polymerase subunit delta YP_001835189.1 463603 D 516950 CDS YP_001835190.1 182683443 6218335 464595..466202 1 NC_010582.1 CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer; CTP synthetase 466202 pyrG 6218335 pyrG Streptococcus pneumoniae CGSP14 CTP synthetase YP_001835190.1 464595 D 516950 CDS YP_001835191.1 182683444 6217975 complement(466761..468392) 1 NC_010582.1 Na/Pi cotransporter II-like protein 468392 6217975 SPCG_0474 Streptococcus pneumoniae CGSP14 Na/Pi cotransporter II-like protein YP_001835191.1 466761 R 516950 CDS YP_001835192.1 182683445 6218189 468594..468704 1 NC_010582.1 hypothetical protein 468704 6218189 SPCG_0475 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835192.1 468594 D 516950 CDS YP_001835193.1 182683446 6218196 468685..473664 1 NC_010582.1 endo-beta-N-acetylglucosaminidase 473664 6218196 SPCG_0476 Streptococcus pneumoniae CGSP14 endo-beta-N-acetylglucosaminidase YP_001835193.1 468685 D 516950 CDS YP_001835194.1 182683447 6217618 473754..474950 1 NC_010582.1 Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway; phosphoglycerate kinase 474950 pgk 6217618 pgk Streptococcus pneumoniae CGSP14 phosphoglycerate kinase YP_001835194.1 473754 D 516950 CDS YP_001835195.1 182683448 6217712 475086..475613 1 NC_010582.1 hypothetical protein 475613 6217712 SPCG_0478 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835195.1 475086 D 516950 CDS YP_001835196.1 182683449 6218297 475690..476046 1 NC_010582.1 MerR family transcriptional regulator 476046 glnR 6218297 glnR Streptococcus pneumoniae CGSP14 MerR family transcriptional regulator YP_001835196.1 475690 D 516950 CDS YP_001835197.1 182683450 6218347 476083..477429 1 NC_010582.1 glutamine synthetase, type I 477429 glnA 6218347 glnA Streptococcus pneumoniae CGSP14 glutamine synthetase, type I YP_001835197.1 476083 D 516950 CDS YP_001835198.1 182683451 6218201 477902..478039 1 NC_010582.1 hypothetical protein 478039 6218201 SPCG_0481 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835198.1 477902 D 516950 CDS YP_001835199.1 182683452 6216540 478210..479502 1 NC_010582.1 type I restriction-modification system subunit S 479502 hsdS 6216540 hsdS Streptococcus pneumoniae CGSP14 type I restriction-modification system subunit S YP_001835199.1 478210 D 516950 CDS YP_001835200.1 182683453 6216546 complement(479450..481000) 1 NC_010582.1 type I restriction-modification system subunit S 481000 hsdS 6216546 hsdS Streptococcus pneumoniae CGSP14 type I restriction-modification system subunit S YP_001835200.1 479450 R 516950 CDS YP_001835201.1 182683454 6217525 complement(481000..482463) 1 NC_010582.1 type I restriction-modification system, M subunit 482463 hsdM 6217525 hsdM Streptococcus pneumoniae CGSP14 type I restriction-modification system, M subunit YP_001835201.1 481000 R 516950 CDS YP_001835202.1 182683455 6216912 complement(482476..484809) 1 NC_010582.1 type I restriction-modification system, R subunit 484809 hsdR 6216912 hsdR Streptococcus pneumoniae CGSP14 type I restriction-modification system, R subunit YP_001835202.1 482476 R 516950 CDS YP_001835203.1 182683456 6218467 complement(485159..485287) 1 NC_010582.1 hypothetical protein 485287 6218467 SPCG_0486 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835203.1 485159 R 516950 CDS YP_001835204.1 182683457 6217519 485488..485925 1 NC_010582.1 hypothetical protein 485925 6217519 SPCG_0487 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835204.1 485488 D 516950 CDS YP_001835205.1 182683458 6218184 486056..487123 1 NC_010582.1 Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons; heat-inducible transcription repressor 487123 hrcA 6218184 hrcA Streptococcus pneumoniae CGSP14 heat-inducible transcription repressor YP_001835205.1 486056 D 516950 CDS YP_001835206.1 182683459 6216452 487126..487674 1 NC_010582.1 with DnaK and DnaJ acts in response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins; may act as a thermosensor; heat shock protein GrpE 487674 grpE 6216452 grpE Streptococcus pneumoniae CGSP14 heat shock protein GrpE YP_001835206.1 487126 D 516950 CDS YP_001835207.1 182683460 6216882 488154..489977 1 NC_010582.1 heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria; molecular chaperone DnaK 489977 dnaK 6216882 dnaK Streptococcus pneumoniae CGSP14 molecular chaperone DnaK YP_001835207.1 488154 D 516950 CDS YP_001835208.1 182683461 6217808 491122..492258 1 NC_010582.1 chaperone Hsp40; co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion; chaperone protein DnaJ 492258 6217808 SPCG_0491 Streptococcus pneumoniae CGSP14 chaperone protein DnaJ YP_001835208.1 491122 D 516950 CDS YP_001835209.1 182683462 6217706 complement(492948..493235) 1 NC_010582.1 hypothetical protein 493235 6217706 SPCG_0492 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835209.1 492948 R 516950 CDS YP_001835210.1 182683463 6217218 complement(493245..493655) 1 NC_010582.1 HIT family protein 493655 6217218 SPCG_0493 Streptococcus pneumoniae CGSP14 HIT family protein YP_001835210.1 493245 R 516950 CDS YP_001835211.1 182683464 6218590 493723..494454 1 NC_010582.1 ABC transporter ATP-binding protein 494454 6218590 SPCG_0494 Streptococcus pneumoniae CGSP14 ABC transporter ATP-binding protein YP_001835211.1 493723 D 516950 CDS YP_001835212.1 182683465 6218329 494451..495500 1 NC_010582.1 ABC transporter permease 495500 6218329 SPCG_0495 Streptococcus pneumoniae CGSP14 ABC transporter permease YP_001835212.1 494451 D 516950 CDS YP_001835213.1 182683466 6217897 complement(495668..495997) 1 NC_010582.1 blpT protein, fusion 495997 blpT 6217897 blpT Streptococcus pneumoniae CGSP14 blpT protein, fusion YP_001835213.1 495668 R 516950 CDS YP_001835214.1 182683467 6216891 496274..496612 1 NC_010582.1 blpS protein 496612 blpS 6216891 blpS Streptococcus pneumoniae CGSP14 blpS protein YP_001835214.1 496274 D 516950 CDS YP_001835215.1 182683468 6217810 496617..497354 1 NC_010582.1 response regulator BlpR 497354 6217810 SPCG_0498 Streptococcus pneumoniae CGSP14 response regulator BlpR YP_001835215.1 496617 D 516950 CDS YP_001835216.1 182683469 6216648 497368..498708 1 NC_010582.1 sensor histidine kinase BlpH 498708 6216648 SPCG_0499 Streptococcus pneumoniae CGSP14 sensor histidine kinase BlpH YP_001835216.1 497368 D 516950 CDS YP_001835217.1 182683470 6217916 complement(498965..500326) 1 NC_010582.1 blpC ABC transporter 500326 6217916 SPCG_0500 Streptococcus pneumoniae CGSP14 blpC ABC transporter YP_001835217.1 498965 R 516950 CDS YP_001835218.1 182683471 6217270 complement(500337..502496) 1 NC_010582.1 competence factor transporting ATP-binding protein/permease ComA 502496 6217270 SPCG_0501 Streptococcus pneumoniae CGSP14 competence factor transporting ATP-binding protein/permease ComA YP_001835218.1 500337 R 516950 CDS YP_001835219.1 182683472 6218508 502771..503001 1 NC_010582.1 bacteriocin BlpU 503001 blpU 6218508 blpU Streptococcus pneumoniae CGSP14 bacteriocin BlpU YP_001835219.1 502771 D 516950 CDS YP_001835220.1 182683473 6218466 503581..503985 1 NC_010582.1 immunity protein BlpL 503985 blpL 6218466 blpL Streptococcus pneumoniae CGSP14 immunity protein BlpL YP_001835220.1 503581 D 516950 CDS YP_001835221.1 182683474 6218427 504183..504371 1 NC_010582.1 IS1381 transposase protein A, truncation 504371 6218427 SPCG_0504 Streptococcus pneumoniae CGSP14 IS1381 transposase protein A, truncation YP_001835221.1 504183 D 516950 CDS YP_001835222.1 182683475 6218354 504599..504988 1 NC_010582.1 IS1381 transposase protein B 504988 6218354 SPCG_0505 Streptococcus pneumoniae CGSP14 IS1381 transposase protein B YP_001835222.1 504599 D 516950 CDS YP_001835223.1 182683476 6218198 505190..505444 1 NC_010582.1 bacteriocin BlpM 505444 blpM 6218198 blpM Streptococcus pneumoniae CGSP14 bacteriocin BlpM YP_001835223.1 505190 D 516950 CDS YP_001835224.1 182683477 6218127 505460..505663 1 NC_010582.1 blpN protein 505663 blpN 6218127 blpN Streptococcus pneumoniae CGSP14 blpN protein YP_001835224.1 505460 D 516950 CDS YP_001835225.1 182683478 6218002 505895..506056 1 NC_010582.1 bacteriocin BlpO 506056 blpO 6218002 blpO Streptococcus pneumoniae CGSP14 bacteriocin BlpO YP_001835225.1 505895 D 516950 CDS YP_001835226.1 182683479 6217974 507050..507448 1 NC_010582.1 immunity protein BlpX 507448 blpX 6217974 blpX Streptococcus pneumoniae CGSP14 immunity protein BlpX YP_001835226.1 507050 D 516950 CDS YP_001835227.1 182683480 6217935 507500..508189 1 NC_010582.1 immunity protein BlpY 508189 blpY 6217935 blpY Streptococcus pneumoniae CGSP14 immunity protein BlpY YP_001835227.1 507500 D 516950 CDS YP_001835228.1 182683481 6217917 508231..508464 1 NC_010582.1 blpZ protein, fusion 508464 blpZ 6217917 blpZ Streptococcus pneumoniae CGSP14 blpZ protein, fusion YP_001835228.1 508231 D 516950 CDS YP_001835229.1 182683482 6217912 508615..509226 1 NC_010582.1 hypothetical protein 509226 6217912 SPCG_0512 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835229.1 508615 D 516950 CDS YP_001835230.1 182683483 6217818 509387..510181 1 NC_010582.1 hypothetical protein 510181 6217818 SPCG_0513 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835230.1 509387 D 516950 CDS YP_001835231.1 182683484 6217765 510178..510813 1 NC_010582.1 tRNA (guanine-N(7)-)-methyltransferase; catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA by transferring the methyl residue from S-adenosyl-L-methionine; tRNA (guanine-N(7)-)-methyltransferase 510813 trmB 6217765 trmB Streptococcus pneumoniae CGSP14 tRNA (guanine-N(7)-)-methyltransferase YP_001835231.1 510178 D 516950 CDS YP_001835232.1 182683485 6217750 510868..511419 1 NC_010582.1 in Streptococcus pneumoniae this gene was found to be essential; structure determination of the Streptococcus protein shows that it is similar to a number of other proteins; hypothetical protein 511419 6217750 SPCG_0515 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835232.1 510868 D 516950 CDS YP_001835233.1 182683486 6217609 511463..512599 1 NC_010582.1 modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination; transcription elongation factor NusA 512599 nusA 6217609 nusA Streptococcus pneumoniae CGSP14 transcription elongation factor NusA YP_001835233.1 511463 D 516950 CDS YP_001835234.1 182683487 6217604 512621..512914 1 NC_010582.1 hypothetical protein 512914 6217604 SPCG_0517 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835234.1 512621 D 516950 CDS YP_001835235.1 182683488 6217560 512907..513206 1 NC_010582.1 hypothetical protein 513206 6217560 SPCG_0518 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835235.1 512907 D 516950 CDS YP_001835236.1 182683489 6217501 513223..516015 1 NC_010582.1 Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; translation initiation factor IF-2 516015 infB 6217501 infB Streptococcus pneumoniae CGSP14 translation initiation factor IF-2 YP_001835236.1 513223 D 516950 CDS YP_001835237.1 182683490 6217485 516239..516616 1 NC_010582.1 associates with free 30S ribosomal subunits; essential for efficient processing of 16S rRNA; in Escherichia coli rbfA is induced by cold shock; ribosome-binding factor A 516616 rbfA 6217485 rbfA Streptococcus pneumoniae CGSP14 ribosome-binding factor A YP_001835237.1 516239 D 516950 CDS YP_001835238.1 182683491 6217444 516859..517674 1 NC_010582.1 hypothetical protein 517674 6217444 SPCG_0521 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835238.1 516859 D 516950 CDS YP_001835239.1 182683492 6217436 complement(518045..518278) 1 NC_010582.1 hypothetical protein 518278 6217436 SPCG_0522 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835239.1 518045 R 516950 CDS YP_001835240.1 182683493 6217418 518297..518542 1 NC_010582.1 hypothetical protein 518542 6217418 SPCG_0523 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835240.1 518297 D 516950 CDS YP_001835241.1 182683494 6217402 518542..519876 1 NC_010582.1 hypothetical protein 519876 6217402 SPCG_0524 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835241.1 518542 D 516950 CDS YP_001835242.1 182683495 6217310 519886..520140 1 NC_010582.1 hypothetical protein 520140 6217310 SPCG_0525 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835242.1 519886 D 516950 CDS YP_001835243.1 182683496 6217274 520236..520631 1 NC_010582.1 hypothetical protein 520631 6217274 SPCG_0526 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835243.1 520236 D 516950 CDS YP_001835244.1 182683497 6217262 521004..521438 1 NC_010582.1 hypothetical protein 521438 6217262 SPCG_0527 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835244.1 521004 D 516950 CDS YP_001835245.1 182683498 6217232 521272..521841 1 NC_010582.1 hypothetical protein 521841 6217232 SPCG_0528 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835245.1 521272 D 516950 CDS YP_001835246.1 182683499 6217195 521478..522038 1 NC_010582.1 acetyltransferase 522038 6217195 SPCG_0529 Streptococcus pneumoniae CGSP14 acetyltransferase YP_001835246.1 521478 D 516950 CDS YP_001835247.1 182683500 6217193 522023..522616 1 NC_010582.1 hypothetical protein 522616 6217193 SPCG_0530 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835247.1 522023 D 516950 CDS YP_001835248.1 182683501 6217189 522609..525260 1 NC_010582.1 valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain; valyl-tRNA synthetase 525260 valS 6217189 valS Streptococcus pneumoniae CGSP14 valyl-tRNA synthetase YP_001835248.1 522609 D 516950 CDS YP_001835249.1 182683502 6217168 525341..525505 1 NC_010582.1 type II DNA modification methyltransferase, truncation 525505 6217168 SPCG_0532 Streptococcus pneumoniae CGSP14 type II DNA modification methyltransferase, truncation YP_001835249.1 525341 D 516950 CDS YP_001835250.1 182683503 6217157 complement(525453..525548) 1 NC_010582.1 hypothetical protein 525548 6217157 SPCG_0533 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835250.1 525453 R 516950 CDS YP_001835251.1 182683504 6217123 525556..527160 1 NC_010582.1 hypothetical protein 527160 6217123 SPCG_0534 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835251.1 525556 D 516950 CDS YP_001835252.1 182683505 6217112 527540..528343 1 NC_010582.1 cell filamentation protein Fic-like protein 528343 6217112 SPCG_0535 Streptococcus pneumoniae CGSP14 cell filamentation protein Fic-like protein YP_001835252.1 527540 D 516950 CDS YP_001835253.1 182683506 6217074 complement(528459..529040) 1 NC_010582.1 IS3-Spn1 transposase, truncation 529040 6217074 SPCG_0536 Streptococcus pneumoniae CGSP14 IS3-Spn1 transposase, truncation YP_001835253.1 528459 R 516950 CDS YP_001835254.1 182683507 6217069 complement(529517..529729) 1 NC_010582.1 degenerate transposase 529729 6217069 SPCG_0537 Streptococcus pneumoniae CGSP14 degenerate transposase YP_001835254.1 529517 R 516950 CDS YP_001835255.1 182683508 6217064 530200..531348 1 NC_010582.1 hypothetical protein 531348 6217064 SPCG_0538 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835255.1 530200 D 516950 CDS YP_001835256.1 182683509 6217049 531444..531539 1 NC_010582.1 hypothetical protein 531539 6217049 SPCG_0539 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835256.1 531444 D 516950 CDS YP_001835257.1 182683510 6217003 531564..532106 1 NC_010582.1 hypothetical protein 532106 6217003 SPCG_0540 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835257.1 531564 D 516950 CDS YP_001835258.1 182683511 6216999 532130..532762 1 NC_010582.1 hypothetical protein 532762 6216999 SPCG_0541 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835258.1 532130 D 516950 CDS YP_001835259.1 182683512 6216996 533062..533901 1 NC_010582.1 transcription antiterminator Lict 533901 licT 6216996 licT Streptococcus pneumoniae CGSP14 transcription antiterminator Lict YP_001835259.1 533062 D 516950 CDS YP_001835260.1 182683513 6216991 533919..535757 1 NC_010582.1 PTS system beta-glucosides-specific transporter subunit IIABC 535757 6216991 SPCG_0543 Streptococcus pneumoniae CGSP14 PTS system beta-glucosides-specific transporter subunit IIABC YP_001835260.1 533919 D 516950 CDS YP_001835261.1 182683514 6216986 535770..537185 1 NC_010582.1 6-phospho-beta-glucosidase 537185 6216986 SPCG_0544 Streptococcus pneumoniae CGSP14 6-phospho-beta-glucosidase YP_001835261.1 535770 D 516950 CDS YP_001835262.1 182683515 6216979 537695..538822 1 NC_010582.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily; phenylalanyl-tRNA synthetase subunit alpha 538822 pheS 6216979 pheS Streptococcus pneumoniae CGSP14 phenylalanyl-tRNA synthetase subunit alpha YP_001835262.1 537695 D 516950 CDS YP_001835263.1 182683516 6216930 538822..539331 1 NC_010582.1 acetyltransferase 539331 6216930 SPCG_0546 Streptococcus pneumoniae CGSP14 acetyltransferase YP_001835263.1 538822 D 516950 CDS YP_001835264.1 182683517 6216918 539408..541813 1 NC_010582.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily; phenylalanyl-tRNA synthetase subunit beta 541813 pheT 6216918 pheT Streptococcus pneumoniae CGSP14 phenylalanyl-tRNA synthetase subunit beta YP_001835264.1 539408 D 516950 CDS YP_001835265.1 182683518 6216917 complement(541881..542882) 1 NC_010582.1 hypothetical protein 542882 6216917 SPCG_0548 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835265.1 541881 R 516950 CDS YP_001835266.1 182683519 6216880 543038..543532 1 NC_010582.1 IS1239 transposase, truncation 543532 6216880 SPCG_0549 Streptococcus pneumoniae CGSP14 IS1239 transposase, truncation YP_001835266.1 543038 D 516950 CDS YP_001835267.1 182683520 6216868 543611..543877 1 NC_010582.1 transcriptional regulator 543877 6216868 SPCG_0550 Streptococcus pneumoniae CGSP14 transcriptional regulator YP_001835267.1 543611 D 516950 CDS YP_001835268.1 182683521 6216859 543958..546387 1 NC_010582.1 catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine to form methionine; 5- methyltetrahydropteroyltriglutamate/homocysteine S-methyltransferase 546387 metE 6216859 metE Streptococcus pneumoniae CGSP14 5- methyltetrahydropteroyltriglutamate/homocysteine S-methyltransferase YP_001835268.1 543958 D 516950 CDS YP_001835269.1 182683522 6216853 546451..547317 1 NC_010582.1 5,10-methylenetetrahydrofolate reductase 547317 metF 6216853 metF Streptococcus pneumoniae CGSP14 5,10-methylenetetrahydrofolate reductase YP_001835269.1 546451 D 516950 CDS YP_001835270.1 182683523 6216845 547888..550215 1 NC_010582.1 polynucleotide phosphorylase/polyadenylase 550215 pnpA 6216845 pnpA Streptococcus pneumoniae CGSP14 polynucleotide phosphorylase/polyadenylase YP_001835270.1 547888 D 516950 CDS YP_001835271.1 182683524 6216837 550231..550848 1 NC_010582.1 serine acetyltransferase 550848 cysE 6216837 cysE Streptococcus pneumoniae CGSP14 serine acetyltransferase YP_001835271.1 550231 D 516950 CDS YP_001835272.1 182683525 6216797 550860..551744 1 NC_010582.1 acetyltransferase 551744 6216797 SPCG_0555 Streptococcus pneumoniae CGSP14 acetyltransferase YP_001835272.1 550860 D 516950 CDS YP_001835273.1 182683526 6216792 551831..553174 1 NC_010582.1 catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA; cysteinyl-tRNA synthetase 553174 cysS 6216792 cysS Streptococcus pneumoniae CGSP14 cysteinyl-tRNA synthetase YP_001835273.1 551831 D 516950 CDS YP_001835274.1 182683527 6216790 553167..553553 1 NC_010582.1 hypothetical protein 553553 6216790 SPCG_0557 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835274.1 553167 D 516950 CDS YP_001835275.1 182683528 6216789 553557..554441 1 NC_010582.1 leucine-rich protein 554441 6216789 SPCG_0558 Streptococcus pneumoniae CGSP14 leucine-rich protein YP_001835275.1 553557 D 516950 CDS YP_001835276.1 182683529 6216752 554905..555282 1 NC_010582.1 hypothetical protein 555282 6216752 SPCG_0559 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835276.1 554905 D 516950 CDS YP_001835277.1 182683530 6216705 555953..557230 1 NC_010582.1 transmembrane protein Vexp1 557230 6216705 SPCG_0560 Streptococcus pneumoniae CGSP14 transmembrane protein Vexp1 YP_001835277.1 555953 D 516950 CDS YP_001835278.1 182683531 6216670 557243..557890 1 NC_010582.1 ABC transporter ATP-binding protein 557890 6216670 SPCG_0561 Streptococcus pneumoniae CGSP14 ABC transporter ATP-binding protein YP_001835278.1 557243 D 516950 CDS YP_001835279.1 182683532 6216637 557942..559321 1 NC_010582.1 transmembrane protein Vexp3 559321 6216637 SPCG_0562 Streptococcus pneumoniae CGSP14 transmembrane protein Vexp3 YP_001835279.1 557942 D 516950 CDS YP_001835280.1 182683533 6216619 559492..559584 1 NC_010582.1 pep27 protein 559584 pep27 6216619 pep27 Streptococcus pneumoniae CGSP14 pep27 protein YP_001835280.1 559492 D 516950 CDS YP_001835281.1 182683534 6216593 559633..560289 1 NC_010582.1 DNA-binding response regulator VncR 560289 vncR 6216593 vncR Streptococcus pneumoniae CGSP14 DNA-binding response regulator VncR YP_001835281.1 559633 D 516950 CDS YP_001835282.1 182683535 6216585 560286..561614 1 NC_010582.1 sensor histidine kinase VncS 561614 vncS 6216585 vncS Streptococcus pneumoniae CGSP14 sensor histidine kinase VncS YP_001835282.1 560286 D 516950 CDS YP_001835283.1 182683536 6216580 561755..562636 1 NC_010582.1 catalyzes the formation of glycerone phosphate and glyceraldehyde 3-phosphate from fructose 1,6, bisphosphate; fructose-bisphosphate aldolase 562636 fba 6216580 fba Streptococcus pneumoniae CGSP14 fructose-bisphosphate aldolase YP_001835283.1 561755 D 516950 CDS YP_001835284.1 182683537 6216565 complement(562957..564159) 1 NC_010582.1 oxidoreductase 564159 6216565 SPCG_0567 Streptococcus pneumoniae CGSP14 oxidoreductase YP_001835284.1 562957 R 516950 CDS YP_001835285.1 182683538 6216478 complement(564442..565101) 1 NC_010582.1 amino acid ABC transporter permease 565101 6216478 SPCG_0568 Streptococcus pneumoniae CGSP14 amino acid ABC transporter permease YP_001835285.1 564442 R 516950 CDS YP_001835286.1 182683539 6216468 complement(565111..565788) 1 NC_010582.1 amino acid ABC transporter permease 565788 6216468 SPCG_0569 Streptococcus pneumoniae CGSP14 amino acid ABC transporter permease YP_001835286.1 565111 R 516950 CDS YP_001835287.1 182683540 6216453 complement(565801..566682) 1 NC_010582.1 amino acid ABC transporter amino acid-binding protein 566682 6216453 SPCG_0570 Streptococcus pneumoniae CGSP14 amino acid ABC transporter amino acid-binding protein YP_001835287.1 565801 R 516950 CDS YP_001835288.1 182683541 6216451 complement(566606..567376) 1 NC_010582.1 amino acid ABC transporter ATP-binding protein 567376 6216451 SPCG_0571 Streptococcus pneumoniae CGSP14 amino acid ABC transporter ATP-binding protein YP_001835288.1 566606 R 516950 CDS YP_001835289.1 182683542 6216445 567629..569863 1 NC_010582.1 single-stranded-DNA-specific exonuclease RecJ 569863 recJ 6216445 recJ Streptococcus pneumoniae CGSP14 single-stranded-DNA-specific exonuclease RecJ YP_001835289.1 567629 D 516950 CDS YP_001835290.1 182683543 6216410 570038..571699 1 NC_010582.1 metallo-beta-lactamase superfamily protein 571699 6216410 SPCG_0573 Streptococcus pneumoniae CGSP14 metallo-beta-lactamase superfamily protein YP_001835290.1 570038 D 516950 CDS YP_001835291.1 182683544 6218364 571768..572547 1 NC_010582.1 tributyrin esterase 572547 estA 6218364 estA Streptococcus pneumoniae CGSP14 tributyrin esterase YP_001835291.1 571768 D 516950 CDS YP_001835292.1 182683545 6217104 572660..573880 1 NC_010582.1 beta-lactam resistance factor 573880 murM 6217104 murM Streptococcus pneumoniae CGSP14 beta-lactam resistance factor YP_001835292.1 572660 D 516950 CDS YP_001835293.1 182683546 6217766 573885..575117 1 NC_010582.1 beta-lactam resistance factor 575117 murN 6217766 murN Streptococcus pneumoniae CGSP14 beta-lactam resistance factor YP_001835293.1 573885 D 516950 CDS YP_001835294.1 182683547 6217148 575175..575897 1 NC_010582.1 hypothetical protein 575897 6217148 SPCG_0577 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835294.1 575175 D 516950 CDS YP_001835295.1 182683548 6217024 575937..577784 1 NC_010582.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision; excinuclease ABC subunit C 577784 uvrC 6217024 uvrC Streptococcus pneumoniae CGSP14 excinuclease ABC subunit C YP_001835295.1 575937 D 516950 CDS YP_001835296.1 182683549 6216831 577834..578271 1 NC_010582.1 hypothetical protein 578271 6216831 SPCG_0579 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835296.1 577834 D 516950 CDS YP_001835297.1 182683550 6216879 578272..578607 1 NC_010582.1 hypothetical protein 578607 6216879 SPCG_0580 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835297.1 578272 D 516950 CDS YP_001835298.1 182683551 6217454 complement(578791..579606) 1 NC_010582.1 amino acid ABC transporter amino acid-binding protein 579606 6217454 SPCG_0581 Streptococcus pneumoniae CGSP14 amino acid ABC transporter amino acid-binding protein YP_001835298.1 578791 R 516950 CDS YP_001835299.1 182683552 6217493 579665..579775 1 NC_010582.1 hypothetical protein 579775 6217493 SPCG_0582 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835299.1 579665 D 516950 CDS YP_001835300.1 182683553 6216985 579762..580367 1 NC_010582.1 nitroreductase family protein 580367 nrd 6216985 nrd Streptococcus pneumoniae CGSP14 nitroreductase family protein YP_001835300.1 579762 D 516950 CDS YP_001835301.1 182683554 6218124 580380..581780 1 NC_010582.1 divalent metal ion-dependent extracellular dipeptidase; able to hydrolyze a broad range of dipeptides but no tri-, tetra-, or larger oligopeptides; differences in the amino acid specificity of the cleavage site varies between species; similar to succinyl-diaminopimelate desuccinylases; dipeptidase PepV 581780 pepV 6218124 pepV Streptococcus pneumoniae CGSP14 dipeptidase PepV YP_001835301.1 580380 D 516950 CDS YP_001835302.1 182683555 6217190 581834..582412 1 NC_010582.1 hypothetical protein 582412 6217190 SPCG_0585 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835302.1 581834 D 516950 CDS YP_001835303.1 182683556 6218592 582536..582724 1 NC_010582.1 hypothetical protein 582724 6218592 SPCG_0586 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835303.1 582536 D 516950 CDS YP_001835304.1 182683557 6218230 583015..584355 1 NC_010582.1 branched-chain amino acid transport system II carrier protein 584355 brnQ 6218230 brnQ Streptococcus pneumoniae CGSP14 branched-chain amino acid transport system II carrier protein YP_001835304.1 583015 D 516950 CDS YP_001835305.1 182683558 6217191 584559..585596 1 NC_010582.1 hypothetical protein 585596 6217191 SPCG_0588 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835305.1 584559 D 516950 CDS YP_001835306.1 182683559 6217018 585565..586068 1 NC_010582.1 HIT family protein 586068 6217018 SPCG_0589 Streptococcus pneumoniae CGSP14 HIT family protein YP_001835306.1 585565 D 516950 CDS YP_001835307.1 182683560 6217057 586071..586787 1 NC_010582.1 hypothetical protein 586787 6217057 SPCG_0590 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835307.1 586071 D 516950 CDS YP_001835308.1 182683561 6217726 587096..587521 1 NC_010582.1 binds directly to 23S ribosomal RNA; 50S ribosomal protein L11 587521 rplK 6217726 rplK Streptococcus pneumoniae CGSP14 50S ribosomal protein L11 YP_001835308.1 587096 D 516950 CDS YP_001835309.1 182683562 6218350 587729..588418 1 NC_010582.1 in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA; 50S ribosomal protein L1 588418 rplA 6218350 rplA Streptococcus pneumoniae CGSP14 50S ribosomal protein L1 YP_001835309.1 587729 D 516950 CDS YP_001835310.1 182683563 6217019 589020..589532 1 NC_010582.1 hypothetical protein 589532 6217019 SPCG_0593 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835310.1 589020 D 516950 CDS YP_001835311.1 182683564 6218343 590577..591569 1 NC_010582.1 ABC transporter ATP-binding protein 591569 6218343 SPCG_0594 Streptococcus pneumoniae CGSP14 ABC transporter ATP-binding protein YP_001835311.1 590577 D 516950 CDS YP_001835312.1 182683565 6216709 591529..592389 1 NC_010582.1 membrane protein 592389 6216709 SPCG_0595 Streptococcus pneumoniae CGSP14 membrane protein YP_001835312.1 591529 D 516950 CDS YP_001835313.1 182683566 6216635 592391..593176 1 NC_010582.1 hypothetical protein 593176 6216635 SPCG_0596 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835313.1 592391 D 516950 CDS YP_001835314.1 182683567 6216572 593274..593492 1 NC_010582.1 hypothetical protein 593492 6216572 SPCG_0597 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835314.1 593274 D 516950 CDS YP_001835315.1 182683568 6216993 593429..593638 1 NC_010582.1 hypothetical protein 593638 6216993 SPCG_0598 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835315.1 593429 D 516950 CDS YP_001835316.1 182683569 6218240 594362..600796 1 NC_010582.1 serine protease 600796 prtA 6218240 prtA Streptococcus pneumoniae CGSP14 serine protease YP_001835316.1 594362 D 516950 CDS YP_001835317.1 182683570 6216872 601407..601904 1 NC_010582.1 PTS system transporter subunit IIA 601904 6216872 SPCG_0600 Streptococcus pneumoniae CGSP14 PTS system transporter subunit IIA YP_001835317.1 601407 D 516950 CDS YP_001835318.1 182683571 6217219 601942..602247 1 NC_010582.1 PTS system transporter subunit IIB 602247 6217219 SPCG_0601 Streptococcus pneumoniae CGSP14 PTS system transporter subunit IIB YP_001835318.1 601942 D 516950 CDS YP_001835319.1 182683572 6216828 602295..603770 1 NC_010582.1 PTS system transporter subunit IIC 603770 6216828 SPCG_0602 Streptococcus pneumoniae CGSP14 PTS system transporter subunit IIC YP_001835319.1 602295 D 516950 CDS YP_001835320.1 182683573 6216512 604120..610821 1 NC_010582.1 beta-galactosidase 610821 bgaA 6216512 bgaA Streptococcus pneumoniae CGSP14 beta-galactosidase YP_001835320.1 604120 D 516950 CDS YP_001835321.1 182683574 6217911 complement(611131..611685) 1 NC_010582.1 degenerate transposase 611685 6217911 SPCG_0604 Streptococcus pneumoniae CGSP14 degenerate transposase YP_001835321.1 611131 R 516950 CDS YP_001835322.1 182683575 6216583 complement(611673..611918) 1 NC_010582.1 degenerate transposase 611918 6216583 SPCG_0605 Streptococcus pneumoniae CGSP14 degenerate transposase YP_001835322.1 611673 R 516950 CDS YP_001835323.1 182683577 6218231 complement(612129..612449) 1 NC_010582.1 hypothetical protein 612449 6218231 SPCG_0606 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835323.1 612129 R 516950 CDS YP_001835324.1 182683576 6218322 612424..613089 1 NC_010582.1 hypothetical protein 613089 6218322 SPCG_0607 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835324.1 612424 D 516950 CDS YP_001835325.1 182683578 6216750 613090..613536 1 NC_010582.1 Fe-S oxidoreductase 613536 6216750 SPCG_0608 Streptococcus pneumoniae CGSP14 Fe-S oxidoreductase YP_001835325.1 613090 D 516950 CDS YP_001835326.1 182683579 6217340 613514..614077 1 NC_010582.1 hypothetical protein 614077 6217340 SPCG_0609 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835326.1 613514 D 516950 CDS YP_001835327.1 182683580 6217683 614101..614325 1 NC_010582.1 hypothetical protein 614325 6217683 SPCG_0610 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835327.1 614101 D 516950 CDS YP_001835328.1 182683581 6216530 614300..614401 1 NC_010582.1 hypothetical protein 614401 6216530 SPCG_0611 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835328.1 614300 D 516950 CDS YP_001835329.1 182683582 6216415 614376..616391 1 NC_010582.1 sodium/hydrogen exchanger family protein 616391 6216415 SPCG_0612 Streptococcus pneumoniae CGSP14 sodium/hydrogen exchanger family protein YP_001835329.1 614376 D 516950 CDS YP_001835330.1 182683583 6218306 616555..617430 1 NC_010582.1 ribonuclease BN 617430 6218306 SPCG_0613 Streptococcus pneumoniae CGSP14 ribonuclease BN YP_001835330.1 616555 D 516950 CDS YP_001835331.1 182683584 6217353 617641..618351 1 NC_010582.1 cytochrome c-type biogenesis protein CcdA 618351 ccdA 6217353 ccdA Streptococcus pneumoniae CGSP14 cytochrome c-type biogenesis protein CcdA YP_001835331.1 617641 D 516950 CDS YP_001835332.1 182683585 6217709 618344..618937 1 NC_010582.1 thioredoxin 618937 6217709 SPCG_0615 Streptococcus pneumoniae CGSP14 thioredoxin YP_001835332.1 618344 D 516950 CDS YP_001835333.1 182683586 6217930 618948..620060 1 NC_010582.1 bifunctional methionine sulfoxide reductase A/B 620060 msrA 6217930 msrA Streptococcus pneumoniae CGSP14 bifunctional methionine sulfoxide reductase A/B YP_001835333.1 618948 D 516950 CDS YP_001835334.1 182683587 6217175 620400..621155 1 NC_010582.1 DNA-binding response regulator 621155 6217175 SPCG_0617 Streptococcus pneumoniae CGSP14 DNA-binding response regulator YP_001835334.1 620400 D 516950 CDS YP_001835335.1 182683588 6217893 621152..622843 1 NC_010582.1 sensor histidine kinase 622843 6217893 SPCG_0618 Streptococcus pneumoniae CGSP14 sensor histidine kinase YP_001835335.1 621152 D 516950 CDS YP_001835336.1 182683589 6217145 622938..623522 1 NC_010582.1 hypothetical protein 623522 6217145 SPCG_0619 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835336.1 622938 D 516950 CDS YP_001835337.1 182683590 6217389 623544..629486 1 NC_010582.1 zinc metalloprotease ZmpB 629486 zmpB 6217389 zmpB Streptococcus pneumoniae CGSP14 zinc metalloprotease ZmpB YP_001835337.1 623544 D 516950 CDS YP_001835338.1 182683591 6218188 629547..631268 1 NC_010582.1 chorismate binding protein 631268 6218188 SPCG_0621 Streptococcus pneumoniae CGSP14 chorismate binding protein YP_001835338.1 629547 D 516950 CDS YP_001835339.1 182683592 6217610 631269..631877 1 NC_010582.1 hypothetical protein 631877 6217610 SPCG_0622 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835339.1 631269 D 516950 CDS YP_001835340.1 182683593 6216975 631936..632934 1 NC_010582.1 surface protein 632934 6216975 SPCG_0623 Streptococcus pneumoniae CGSP14 surface protein YP_001835340.1 631936 D 516950 CDS YP_001835341.1 182683594 6217415 633043..634020 1 NC_010582.1 glucokinase 634020 glcK 6217415 glcK Streptococcus pneumoniae CGSP14 glucokinase YP_001835341.1 633043 D 516950 CDS YP_001835342.1 182683595 6218455 634117..634956 1 NC_010582.1 ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived; thymidylate synthase 634956 thyA 6218455 thyA Streptococcus pneumoniae CGSP14 thymidylate synthase YP_001835342.1 634117 D 516950 CDS YP_001835343.1 182683597 6216860 complement(635004..635174) 1 NC_010582.1 hypothetical protein 635174 6216860 SPCG_0626 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835343.1 635004 R 516950 CDS YP_001835344.1 182683596 6217072 635050..635238 1 NC_010582.1 hypothetical protein 635238 6217072 SPCG_0627 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835344.1 635050 D 516950 CDS YP_001835345.1 182683598 6216560 635244..636179 1 NC_010582.1 IPP transferase; isopentenyltransferase; involved in tRNA modification; in Escherichia coli this enzyme catalyzes the addition of a delta2-isopentenyl group from dimethylallyl diphosphate to the N6-nitrogen of adenosine adjacent to the anticodon of tRNA species that read codons starting with uracil; further tRNA modifications may occur; mutations in miaA result in defects in translation efficiency and fidelity; tRNA delta(2)-isopentenylpyrophosphate transferase 636179 miaA 6216560 miaA Streptococcus pneumoniae CGSP14 tRNA delta(2)-isopentenylpyrophosphate transferase YP_001835345.1 635244 D 516950 CDS YP_001835346.1 182683599 6217246 636172..637410 1 NC_010582.1 GTP-binding protein HflX 637410 6217246 SPCG_0629 Streptococcus pneumoniae CGSP14 GTP-binding protein HflX YP_001835346.1 636172 D 516950 CDS YP_001835347.1 182683600 6218533 637403..638026 1 NC_010582.1 hypothetical protein 638026 6218533 SPCG_0630 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835347.1 637403 D 516950 CDS YP_001835348.1 182683601 6216630 638041..638970 1 NC_010582.1 member of metallo-beta-lactamase family; the purified enzyme from Escherichia coli forms dimeric zinc phosphodiesterase; in Bacillus subtilis this protein is a 3'-tRNA processing endoribonuclease and is essential while in Escherichia coli it is not; associates with two zinc ions; ribonuclease Z 638970 6216630 SPCG_0631 Streptococcus pneumoniae CGSP14 ribonuclease Z YP_001835348.1 638041 D 516950 CDS YP_001835349.1 182683602 6218093 638991..639746 1 NC_010582.1 short chain dehydrogenase/reductase family oxidoreductase 639746 6218093 SPCG_0632 Streptococcus pneumoniae CGSP14 short chain dehydrogenase/reductase family oxidoreductase YP_001835349.1 638991 D 516950 CDS YP_001835350.1 182683604 6217809 complement(639800..640798) 1 NC_010582.1 transcriptional regulator 640798 6217809 SPCG_0633 Streptococcus pneumoniae CGSP14 transcriptional regulator YP_001835350.1 639800 R 516950 CDS YP_001835351.1 182683603 6217932 640772..641041 1 NC_010582.1 hypothetical protein 641041 6217932 SPCG_0634 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835351.1 640772 D 516950 CDS YP_001835352.1 182683605 6218210 641041..641421 1 NC_010582.1 hypothetical protein 641421 6218210 SPCG_0635 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835352.1 641041 D 516950 CDS YP_001835353.1 182683606 6216422 641540..641737 1 NC_010582.1 hypothetical protein 641737 6216422 SPCG_0636 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835353.1 641540 D 516950 CDS YP_001835354.1 182683607 6218162 complement(641777..642502) 1 NC_010582.1 ribosomal small subunit pseudouridine synthase A 642502 rsuA 6218162 rsuA Streptococcus pneumoniae CGSP14 ribosomal small subunit pseudouridine synthase A YP_001835354.1 641777 R 516950 CDS YP_001835355.1 182683608 6216906 642643..644505 1 NC_010582.1 elongation factor Tu family protein 644505 6216906 SPCG_0638 Streptococcus pneumoniae CGSP14 elongation factor Tu family protein YP_001835355.1 642643 D 516950 CDS YP_001835356.1 182683609 6217966 644525..644779 1 NC_010582.1 hypothetical protein 644779 6217966 SPCG_0639 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835356.1 644525 D 516950 CDS YP_001835357.1 182683610 6218346 645326..645442 1 NC_010582.1 hypothetical protein 645442 6218346 SPCG_0640 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835357.1 645326 D 516950 CDS YP_001835358.1 182683611 6218542 645513..647534 1 NC_010582.1 hypothetical protein 647534 6218542 SPCG_0641 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835358.1 645513 D 516950 CDS YP_001835359.1 182683612 6218097 647536..648177 1 NC_010582.1 ABC transporter ATP-binding protein 648177 6218097 SPCG_0642 Streptococcus pneumoniae CGSP14 ABC transporter ATP-binding protein YP_001835359.1 647536 D 516950 CDS YP_001835360.1 182683613 6216810 648281..649633 1 NC_010582.1 UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase 649633 murD 6216810 murD Streptococcus pneumoniae CGSP14 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase YP_001835360.1 648281 D 516950 CDS YP_001835361.1 182683614 6216884 649635..650693 1 NC_010582.1 UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; involved in cell wall formation; inner membrane-associated; last step of peptidoglycan synthesis; undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase 650693 murG 6216884 murG Streptococcus pneumoniae CGSP14 undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase YP_001835361.1 649635 D 516950 CDS YP_001835362.1 182683615 6218173 650703..651902 1 NC_010582.1 cell division protein DivIB 651902 divIB 6218173 divIB Streptococcus pneumoniae CGSP14 cell division protein DivIB YP_001835362.1 650703 D 516950 CDS YP_001835363.1 182683616 6217130 652012..652158 1 NC_010582.1 hypothetical protein 652158 6217130 SPCG_0646 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835363.1 652012 D 516950 CDS YP_001835364.1 182683617 6217277 652170..652301 1 NC_010582.1 hypothetical protein 652301 6217277 SPCG_0647 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835364.1 652170 D 516950 CDS YP_001835365.1 182683618 6217089 652642..653490 1 NC_010582.1 hypothetical protein 653490 6217089 SPCG_0648 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835365.1 652642 D 516950 CDS YP_001835366.1 182683619 6216900 653820..654560 1 NC_010582.1 HesA/MoeB/ThiF family protein 654560 6216900 SPCG_0649 Streptococcus pneumoniae CGSP14 HesA/MoeB/ThiF family protein YP_001835366.1 653820 D 516950 CDS YP_001835367.1 182683620 6217498 655000..655875 1 NC_010582.1 ABC transporter ATP-binding protein 655875 6217498 SPCG_0650 Streptococcus pneumoniae CGSP14 ABC transporter ATP-binding protein YP_001835367.1 655000 D 516950 CDS YP_001835368.1 182683621 6217715 655868..656581 1 NC_010582.1 hypothetical protein 656581 6217715 SPCG_0651 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835368.1 655868 D 516950 CDS YP_001835369.1 182683622 6218339 complement(656855..656998) 1 NC_010582.1 hypothetical protein 656998 6218339 SPCG_0652 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835369.1 656855 R 516950 CDS YP_001835370.1 182683623 6217327 657316..658017 1 NC_010582.1 type 1 subfamily; involved in last step of pyrimidine biosynthesis; converts orotidine 5'-phosphate to UMP and carbon dioxide; OMP decarboxylase; OMPDCase; OMPdecase; orotidine 5'-phosphate decarboxylase 658017 pyrF 6217327 pyrF Streptococcus pneumoniae CGSP14 orotidine 5'-phosphate decarboxylase YP_001835370.1 657316 D 516950 CDS YP_001835371.1 182683624 6217993 658051..658683 1 NC_010582.1 involved in fifth step of pyrimidine biosynthesis; converts orotidine 5'-phosphate and diphosphate to orotate and 5-phospho-alpha-D-ribose 1-diphosphate; orotate phosphoribosyltransferase 658683 pyrE 6217993 pyrE Streptococcus pneumoniae CGSP14 orotate phosphoribosyltransferase YP_001835371.1 658051 D 516950 CDS YP_001835372.1 182683625 6217128 659362..660126 1 NC_010582.1 hypothetical protein 660126 6217128 SPCG_0655 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835372.1 659362 D 516950 CDS YP_001835373.1 182683626 6216784 660881..661585 1 NC_010582.1 hypothetical protein 661585 6216784 SPCG_0656 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835373.1 660881 D 516950 CDS YP_001835374.1 182683627 6218525 661582..662229 1 NC_010582.1 ABC transporter ATP-binding protein 662229 6218525 SPCG_0657 Streptococcus pneumoniae CGSP14 ABC transporter ATP-binding protein YP_001835374.1 661582 D 516950 CDS YP_001835375.1 182683628 6218336 complement(662309..663169) 1 NC_010582.1 amino acid (glutamine) ABC transporter substrate binding protein 663169 6218336 SPCG_0658 Streptococcus pneumoniae CGSP14 amino acid (glutamine) ABC transporter substrate binding protein YP_001835375.1 662309 R 516950 CDS YP_001835376.1 182683629 6217697 complement(663181..663939) 1 NC_010582.1 amino acid ABC transporter ATP-binding protein 663939 6217697 SPCG_0659 Streptococcus pneumoniae CGSP14 amino acid ABC transporter ATP-binding protein YP_001835376.1 663181 R 516950 CDS YP_001835377.1 182683630 6216465 complement(663940..664857) 1 NC_010582.1 amino acid ABC transporter permease 664857 6216465 SPCG_0660 Streptococcus pneumoniae CGSP14 amino acid ABC transporter permease YP_001835377.1 663940 R 516950 CDS YP_001835378.1 182683631 6218018 664890..665036 1 NC_010582.1 hypothetical protein 665036 6218018 SPCG_0661 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835378.1 664890 D 516950 CDS YP_001835379.1 182683632 6218396 665164..666654 1 NC_010582.1 class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1; lysyl-tRNA synthetase 666654 lysS 6218396 lysS Streptococcus pneumoniae CGSP14 lysyl-tRNA synthetase YP_001835379.1 665164 D 516950 CDS YP_001835380.1 182683633 6218437 667278..668414 1 NC_010582.1 lactate oxidase 668414 lctO 6218437 lctO Streptococcus pneumoniae CGSP14 lactate oxidase YP_001835380.1 667278 D 516950 CDS YP_001835381.1 182683634 6216554 668971..669639 1 NC_010582.1 transcriptional regulator 669639 6216554 SPCG_0664 Streptococcus pneumoniae CGSP14 transcriptional regulator YP_001835381.1 668971 D 516950 CDS YP_001835382.1 182683635 6216657 complement(669636..669881) 1 NC_010582.1 hypothetical protein 669881 6216657 SPCG_0665 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835382.1 669636 R 516950 CDS YP_001835383.1 182683636 6217806 669944..670747 1 NC_010582.1 catalyzes the formation of 4-methyl-5-(2-phosphoethyl)-thiazole and ADP from 4-methyl-5-(2-hydroxyethyl)-thiazole and ATP; hydroxyethylthiazole kinase 670747 thiM 6217806 thiM Streptococcus pneumoniae CGSP14 hydroxyethylthiazole kinase YP_001835383.1 669944 D 516950 CDS YP_001835384.1 182683637 6216545 670749..671378 1 NC_010582.1 thiamine-phosphate pyrophosphorylase 671378 thiE 6216545 thiE Streptococcus pneumoniae CGSP14 thiamine-phosphate pyrophosphorylase YP_001835384.1 670749 D 516950 CDS YP_001835385.1 182683638 6217729 671937..672497 1 NC_010582.1 hypothetical protein 672497 6217729 SPCG_0668 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835385.1 671937 D 516950 CDS YP_001835386.1 182683639 6217704 672498..673883 1 NC_010582.1 ABC transporter ATP-binding protein 673883 6217704 SPCG_0669 Streptococcus pneumoniae CGSP14 ABC transporter ATP-binding protein YP_001835386.1 672498 D 516950 CDS YP_001835387.1 182683640 6216925 673885..674535 1 NC_010582.1 hypothetical protein 674535 6216925 SPCG_0670 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835387.1 673885 D 516950 CDS YP_001835388.1 182683641 6217226 674546..675238 1 NC_010582.1 transcriptional activator TenA 675238 tenA 6217226 tenA Streptococcus pneumoniae CGSP14 transcriptional activator TenA YP_001835388.1 674546 D 516950 CDS YP_001835389.1 182683642 6218139 675243..675767 1 NC_010582.1 hypothetical protein 675767 6218139 SPCG_0672 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835389.1 675243 D 516950 CDS YP_001835390.1 182683643 6217830 675764..676570 1 NC_010582.1 hydroxyethylthiazole kinase 676570 thiM 6217830 thiM Streptococcus pneumoniae CGSP14 hydroxyethylthiazole kinase YP_001835390.1 675764 D 516950 CDS YP_001835391.1 182683644 6217775 676563..677195 1 NC_010582.1 Condenses 4-methyl-5-(beta-hydroxyethyl)-thiazole monophosphate and 4-amino-5-hydroxymethyl pyrimidine pyrophosphate to form thiamine monophosphate; thiamine-phosphate pyrophosphorylase 677195 thiE 6217775 thiE Streptococcus pneumoniae CGSP14 thiamine-phosphate pyrophosphorylase YP_001835391.1 676563 D 516950 CDS YP_001835392.1 182683645 6216672 complement(677405..678196) 1 NC_010582.1 catalyzes the formation of 4-amino-2-methyl-5-diphosphomethylpyrimidine; phosphomethylpyrimidine kinase 678196 thiD 6216672 thiD Streptococcus pneumoniae CGSP14 phosphomethylpyrimidine kinase YP_001835392.1 677405 R 516950 CDS YP_001835393.1 182683646 6217169 678532..678957 1 NC_010582.1 transcriptional repressor 678957 copY 6217169 copY Streptococcus pneumoniae CGSP14 transcriptional repressor YP_001835393.1 678532 D 516950 CDS YP_001835394.1 182683647 6218136 678968..679339 1 NC_010582.1 hypothetical protein 679339 6218136 SPCG_0677 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835394.1 678968 D 516950 CDS YP_001835395.1 182683648 6217686 679340..681592 1 NC_010582.1 cation transporter E1-E2 family ATPase 681592 ctpA 6217686 ctpA Streptococcus pneumoniae CGSP14 cation transporter E1-E2 family ATPase YP_001835395.1 679340 D 516950 CDS YP_001835396.1 182683649 6216487 681799..683574 1 NC_010582.1 pyruvate oxidase 683574 spxB 6216487 spxB Streptococcus pneumoniae CGSP14 pyruvate oxidase YP_001835396.1 681799 D 516950 CDS YP_001835397.1 182683650 6218591 683685..684032 1 NC_010582.1 hypothetical protein 684032 6218591 SPCG_0680 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835397.1 683685 D 516950 CDS YP_001835398.1 182683651 6217639 complement(684244..684660) 1 NC_010582.1 hypothetical protein 684660 6217639 SPCG_0681 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835398.1 684244 R 516950 CDS YP_001835399.1 182683652 6218151 complement(684689..684955) 1 NC_010582.1 hypothetical protein 684955 6218151 SPCG_0682 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835399.1 684689 R 516950 CDS YP_001835400.1 182683653 6216899 complement(685292..685387) 1 NC_010582.1 hypothetical protein 685387 6216899 SPCG_0683 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835400.1 685292 R 516950 CDS YP_001835401.1 182683654 6217238 685452..685733 1 NC_010582.1 6-phospho-beta-glucosidase 685733 6217238 SPCG_0684 Streptococcus pneumoniae CGSP14 6-phospho-beta-glucosidase YP_001835401.1 685452 D 516950 CDS YP_001835402.1 182683655 6217724 685811..686809 1 NC_010582.1 mannose-6-phosphate isomerase 686809 6217724 SPCG_0685 Streptococcus pneumoniae CGSP14 mannose-6-phosphate isomerase YP_001835402.1 685811 D 516950 CDS YP_001835403.1 182683656 6218308 686793..686996 1 NC_010582.1 hypothetical protein 686996 6218308 SPCG_0686 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835403.1 686793 D 516950 CDS YP_001835404.1 182683657 6218520 complement(686830..688089) 1 NC_010582.1 sodium-dependent transporter 688089 6218520 SPCG_0687 Streptococcus pneumoniae CGSP14 sodium-dependent transporter YP_001835404.1 686830 R 516950 CDS YP_001835405.1 182683658 6217107 complement(688086..688313) 1 NC_010582.1 hypothetical protein 688313 6217107 SPCG_0688 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835405.1 688086 R 516950 CDS YP_001835406.1 182683659 6217326 688412..689152 1 NC_010582.1 MerR family transcriptional regulator 689152 6217326 SPCG_0689 Streptococcus pneumoniae CGSP14 MerR family transcriptional regulator YP_001835406.1 688412 D 516950 CDS YP_001835407.1 182683660 6217359 complement(689181..689636) 1 NC_010582.1 mutT/nudix family protein 689636 6217359 SPCG_0690 Streptococcus pneumoniae CGSP14 mutT/nudix family protein YP_001835407.1 689181 R 516950 CDS YP_001835408.1 182683661 6217594 complement(689656..690849) 1 NC_010582.1 hypothetical protein 690849 6217594 SPCG_0691 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835408.1 689656 R 516950 CDS YP_001835409.1 182683662 6217164 complement(690890..691735) 1 NC_010582.1 hypothetical protein 691735 6217164 SPCG_0692 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835409.1 690890 R 516950 CDS YP_001835410.1 182683663 6217173 691860..692417 1 NC_010582.1 TetR family transcriptional regulator 692417 6217173 SPCG_0693 Streptococcus pneumoniae CGSP14 TetR family transcriptional regulator YP_001835410.1 691860 D 516950 CDS YP_001835411.1 182683664 6218355 692436..692903 1 NC_010582.1 cytidine and deoxycytidylate deaminase family protein 692903 6218355 SPCG_0694 Streptococcus pneumoniae CGSP14 cytidine and deoxycytidylate deaminase family protein YP_001835411.1 692436 D 516950 CDS YP_001835412.1 182683665 6217848 692971..693621 1 NC_010582.1 Catalyzes the formation of uracil and 5-phospho-alpha-D-ribosy 1-diphosphate from UMP and diphosphate; uracil phosphoribosyltransferase 693621 upp 6217848 upp Streptococcus pneumoniae CGSP14 uracil phosphoribosyltransferase YP_001835412.1 692971 D 516950 CDS YP_001835413.1 182683666 6218370 693794..694384 1 NC_010582.1 hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates; ATP-dependent Clp protease proteolytic subunit 694384 clpP 6218370 clpP Streptococcus pneumoniae CGSP14 ATP-dependent Clp protease proteolytic subunit YP_001835413.1 693794 D 516950 CDS YP_001835414.1 182683668 6218031 complement(694381..694479) 1 NC_010582.1 hypothetical protein 694479 6218031 SPCG_0697 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835414.1 694381 R 516950 CDS YP_001835415.1 182683667 6216741 694463..694711 1 NC_010582.1 hypothetical protein 694711 6216741 SPCG_0698 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835415.1 694463 D 516950 CDS YP_001835416.1 182683669 6216802 694813..695973 1 NC_010582.1 branched-chain amino acid ABC transporter substrate-binding protein 695973 6216802 SPCG_0699 Streptococcus pneumoniae CGSP14 branched-chain amino acid ABC transporter substrate-binding protein YP_001835416.1 694813 D 516950 CDS YP_001835417.1 182683670 6217661 696232..697110 1 NC_010582.1 branched-chain amino acid ABC transporter permease 697110 6217661 SPCG_0700 Streptococcus pneumoniae CGSP14 branched-chain amino acid ABC transporter permease YP_001835417.1 696232 D 516950 CDS YP_001835418.1 182683671 6218361 697114..698070 1 NC_010582.1 branched-chain amino acid ABC transporter permease 698070 6218361 SPCG_0701 Streptococcus pneumoniae CGSP14 branched-chain amino acid ABC transporter permease YP_001835418.1 697114 D 516950 CDS YP_001835419.1 182683672 6218314 698070..698834 1 NC_010582.1 branched-chain amino acid ABC transporter ATP-binding protein 698834 6218314 SPCG_0702 Streptococcus pneumoniae CGSP14 branched-chain amino acid ABC transporter ATP-binding protein YP_001835419.1 698070 D 516950 CDS YP_001835420.1 182683673 6218365 698834..699544 1 NC_010582.1 branched-chain amino acid ABC transporter ATP-binding protein 699544 6218365 SPCG_0703 Streptococcus pneumoniae CGSP14 branched-chain amino acid ABC transporter ATP-binding protein YP_001835420.1 698834 D 516950 CDS YP_001835421.1 182683674 6216544 699958..700614 1 NC_010582.1 acetoin utilization protein AcuB 700614 6216544 SPCG_0704 Streptococcus pneumoniae CGSP14 acetoin utilization protein AcuB YP_001835421.1 699958 D 516950 CDS YP_001835422.1 182683675 6216734 700828..701817 1 NC_010582.1 recognizes the termination signals UGA and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF2; in some organisms control of PrfB protein levels is maintained through a +1 ribosomal frameshifting mechanism; this protein is similar to release factor 1; peptide chain release factor 2 701817 prfB 6216734 prfB Streptococcus pneumoniae CGSP14 peptide chain release factor 2 YP_001835422.1 700828 D 516950 CDS YP_001835423.1 182683676 6216668 701835..702527 1 NC_010582.1 cell division ABC transporter ATP-binding protein FtsE 702527 ftsE 6216668 ftsE Streptococcus pneumoniae CGSP14 cell division ABC transporter ATP-binding protein FtsE YP_001835423.1 701835 D 516950 CDS YP_001835424.1 182683677 6216429 702457..703446 1 NC_010582.1 cell division ABC transporter permease FtsX 703446 ftsX 6216429 ftsX Streptococcus pneumoniae CGSP14 cell division ABC transporter permease FtsX YP_001835424.1 702457 D 516950 CDS YP_001835425.1 182683678 6217350 703732..705912 1 NC_010582.1 PTS system transporter subunit IIABC 705912 ptsG 6217350 ptsG Streptococcus pneumoniae CGSP14 PTS system transporter subunit IIABC YP_001835425.1 703732 D 516950 CDS YP_001835426.1 182683679 6217855 705918..706037 1 NC_010582.1 hypothetical protein 706037 6217855 SPCG_0709 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835426.1 705918 D 516950 CDS YP_001835427.1 182683680 6218144 706030..706779 1 NC_010582.1 hypothetical protein 706779 6218144 SPCG_0710 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835427.1 706030 D 516950 CDS YP_001835428.1 182683681 6218363 706919..708262 1 NC_010582.1 DEAD/DEAH box helicase 708262 rheB 6218363 rheB Streptococcus pneumoniae CGSP14 DEAD/DEAH box helicase YP_001835428.1 706919 D 516950 CDS YP_001835429.1 182683682 6218451 708477..709667 1 NC_010582.1 catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase; S-adenosylmethionine synthetase 709667 metK 6218451 metK Streptococcus pneumoniae CGSP14 S-adenosylmethionine synthetase YP_001835429.1 708477 D 516950 CDS YP_001835430.1 182683683 6216486 710220..711155 1 NC_010582.1 catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway; subclass 1A is a dimer formed by two identical PyrD subunits each containing an FMN group; dihydroorotate dehydrogenase 1A 711155 6216486 SPCG_0713 Streptococcus pneumoniae CGSP14 dihydroorotate dehydrogenase 1A YP_001835430.1 710220 D 516950 CDS YP_001835431.1 182683684 6218362 711189..712226 1 NC_010582.1 required for the assembly and function of the DNAX complex which is required for the assembly of the beta subunit onto primed DNA; DNA polymerase III subunit delta 712226 holA 6218362 holA Streptococcus pneumoniae CGSP14 DNA polymerase III subunit delta YP_001835431.1 711189 D 516950 CDS YP_001835432.1 182683685 6217646 712399..713004 1 NC_010582.1 superoxide dismutase, manganese-dependent 713004 sodA 6217646 sodA Streptococcus pneumoniae CGSP14 superoxide dismutase, manganese-dependent YP_001835432.1 712399 D 516950 CDS YP_001835433.1 182683686 6217437 713162..713692 1 NC_010582.1 hypothetical protein 713692 6217437 SPCG_0716 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835433.1 713162 D 516950 CDS YP_001835434.1 182683687 6216443 713713..714798 1 NC_010582.1 23S rRNA m2A2503 methyltransferase; methylates the C2 position of the A2530 nucleotide in 23S rRNA; may be involved in antibiotic resistance; ribosomal RNA large subunit methyltransferase N 714798 6216443 SPCG_0717 Streptococcus pneumoniae CGSP14 ribosomal RNA large subunit methyltransferase N YP_001835434.1 713713 D 516950 CDS YP_001835435.1 182683688 6218547 714798..715280 1 NC_010582.1 vanZF-related protein 715280 6218547 SPCG_0718 Streptococcus pneumoniae CGSP14 vanZF-related protein YP_001835435.1 714798 D 516950 CDS YP_001835436.1 182683689 6218373 715282..716823 1 NC_010582.1 ABC transporter ATP-binding protein 716823 6218373 SPCG_0719 Streptococcus pneumoniae CGSP14 ABC transporter ATP-binding protein YP_001835436.1 715282 D 516950 CDS YP_001835437.1 182683690 6218317 complement(716879..717682) 1 NC_010582.1 cyclophilin type peptidyl-prolyl cis-trans isomerase 717682 ppiA 6218317 ppiA Streptococcus pneumoniae CGSP14 cyclophilin type peptidyl-prolyl cis-trans isomerase YP_001835437.1 716879 R 516950 CDS YP_001835438.1 182683691 6218299 complement(717766..717978) 1 NC_010582.1 hypothetical protein 717978 6218299 SPCG_0721 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835438.1 717766 R 516950 CDS YP_001835439.1 182683692 6216849 complement(718457..718666) 1 NC_010582.1 hypothetical protein 718666 6216849 SPCG_0722 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835439.1 718457 R 516950 CDS YP_001835440.1 182683693 6216876 718836..719123 1 NC_010582.1 30S ribosomal protein S16 719123 rpsP 6216876 rpsP Streptococcus pneumoniae CGSP14 30S ribosomal protein S16 YP_001835440.1 718836 D 516950 CDS YP_001835441.1 182683694 6218195 719127..719366 1 NC_010582.1 KH domain-containing protein 719366 6218195 SPCG_0724 Streptococcus pneumoniae CGSP14 KH domain-containing protein YP_001835441.1 719127 D 516950 CDS YP_001835442.1 182683695 6217273 719931..720731 1 NC_010582.1 hypothetical protein 720731 6217273 SPCG_0725 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835442.1 719931 D 516950 CDS YP_001835443.1 182683696 6218461 720762..721280 1 NC_010582.1 Essential for efficient processing of 16S rRNA; 16S rRNA-processing protein RimM 721280 rimM 6218461 rimM Streptococcus pneumoniae CGSP14 16S rRNA-processing protein RimM YP_001835443.1 720762 D 516950 CDS YP_001835444.1 182683697 6216647 721270..721989 1 NC_010582.1 methylates guanosine-37 in various tRNAs; uses S-adenosyl-L-methionine to transfer methyl group to tRNA; tRNA (guanine-N(1)-)-methyltransferase 721989 trmD 6216647 trmD Streptococcus pneumoniae CGSP14 tRNA (guanine-N(1)-)-methyltransferase YP_001835444.1 721270 D 516950 CDS YP_001835445.1 182683698 6218020 722001..722339 1 NC_010582.1 ATP cone domain-containing protein 722339 6218020 SPCG_0728 Streptococcus pneumoniae CGSP14 ATP cone domain-containing protein YP_001835445.1 722001 D 516950 CDS YP_001835446.1 182683699 6216559 complement(722370..722690) 1 NC_010582.1 hypothetical protein 722690 6216559 SPCG_0729 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835446.1 722370 R 516950 CDS YP_001835447.1 182683700 6217307 722764..723003 1 NC_010582.1 hypothetical protein 723003 6217307 SPCG_0730 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835447.1 722764 D 516950 CDS YP_001835448.1 182683701 6217004 complement(723000..723128) 1 NC_010582.1 hypothetical protein 723128 6217004 SPCG_0731 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835448.1 723000 R 516950 CDS YP_001835449.1 182683702 6217288 complement(723255..723791) 1 NC_010582.1 hypothetical protein 723791 6217288 SPCG_0732 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835449.1 723255 R 516950 CDS YP_001835450.1 182683703 6218036 complement(723964..725334) 1 NC_010582.1 catalyzes the reduction of 2 glutathione to glutathione disulfide; maintains high levels of reduced glutathione in the cytosol; involved in redox regulation and oxidative defense; glutathione reductase 725334 gor 6218036 gor Streptococcus pneumoniae CGSP14 glutathione reductase YP_001835450.1 723964 R 516950 CDS YP_001835451.1 182683704 6218305 725620..726819 1 NC_010582.1 hypothetical protein 726819 6218305 SPCG_0734 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835451.1 725620 D 516950 CDS YP_001835452.1 182683705 6218239 726803..727504 1 NC_010582.1 ABC transporter ATP-binding protein 727504 6218239 SPCG_0735 Streptococcus pneumoniae CGSP14 ABC transporter ATP-binding protein YP_001835452.1 726803 D 516950 CDS YP_001835453.1 182683706 6216348 727506..728765 1 NC_010582.1 hypothetical protein 728765 6216348 SPCG_0736 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835453.1 727506 D 516950 CDS YP_001835454.1 182683707 6218152 728847..730886 1 NC_010582.1 methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content; methionyl-tRNA synthetase 730886 metG 6218152 metG Streptococcus pneumoniae CGSP14 methionyl-tRNA synthetase YP_001835454.1 728847 D 516950 CDS YP_001835455.1 182683708 6216715 731259..731582 1 NC_010582.1 hypothetical protein 731582 6216715 SPCG_0738 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835455.1 731259 D 516950 CDS YP_001835456.1 182683709 6218557 731586..732401 1 NC_010582.1 hypothetical protein 732401 6218557 SPCG_0739 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835456.1 731586 D 516950 CDS YP_001835457.1 182683710 6217484 732473..733402 1 NC_010582.1 aldo/keto reductase family oxidoreductase 733402 6217484 SPCG_0740 Streptococcus pneumoniae CGSP14 aldo/keto reductase family oxidoreductase YP_001835457.1 732473 D 516950 CDS YP_001835458.1 182683711 6217813 733468..733734 1 NC_010582.1 hypothetical protein 733734 6217813 SPCG_0741 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835458.1 733468 D 516950 CDS YP_001835459.1 182683712 6218331 733727..734425 1 NC_010582.1 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis; 3-ketoacyl-ACP reductase 734425 fabG 6218331 fabG Streptococcus pneumoniae CGSP14 3-ketoacyl-ACP reductase YP_001835459.1 733727 D 516950 CDS YP_001835460.1 182683713 6218303 734436..734936 1 NC_010582.1 mutT/nudix family protein 734936 6218303 SPCG_0743 Streptococcus pneumoniae CGSP14 mutT/nudix family protein YP_001835460.1 734436 D 516950 CDS YP_001835461.1 182683714 6217013 734911..735783 1 NC_010582.1 PEP-utilizing enzyme family protein 735783 6217013 SPCG_0744 Streptococcus pneumoniae CGSP14 PEP-utilizing enzyme family protein YP_001835461.1 734911 D 516950 CDS YP_001835462.1 182683715 6218004 735758..736198 1 NC_010582.1 hypothetical protein 736198 6218004 SPCG_0745 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835462.1 735758 D 516950 CDS YP_001835463.1 182683716 6216490 736321..738867 1 NC_010582.1 aminopeptidase N 738867 pepN 6216490 pepN Streptococcus pneumoniae CGSP14 aminopeptidase N YP_001835463.1 736321 D 516950 CDS YP_001835464.1 182683717 6218247 738910..739650 1 NC_010582.1 DNA-binding response regulator CiaR 739650 ciaR 6218247 ciaR Streptococcus pneumoniae CGSP14 DNA-binding response regulator CiaR YP_001835464.1 738910 D 516950 CDS YP_001835465.1 182683718 6218527 739640..740974 1 NC_010582.1 sensor histidine kinase CiaH 740974 ciaH 6218527 ciaH Streptococcus pneumoniae CGSP14 sensor histidine kinase CiaH YP_001835465.1 739640 D 516950 CDS YP_001835466.1 182683720 6217006 complement(741008..741295) 1 NC_010582.1 hypothetical protein 741295 6217006 SPCG_0749 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835466.1 741008 R 516950 CDS YP_001835467.1 182683719 6216870 741294..742364 1 NC_010582.1 hypothetical protein 742364 6216870 SPCG_0750 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835467.1 741294 D 516950 CDS YP_001835468.1 182683721 6216584 742564..745014 1 NC_010582.1 unwinds DNA; bifunctional ATP-dependent DNA helicase/DNA polymerase III subunit epsilon 745014 dinG 6216584 dinG Streptococcus pneumoniae CGSP14 bifunctional ATP-dependent DNA helicase/DNA polymerase III subunit epsilon YP_001835468.1 742564 D 516950 CDS YP_001835469.1 182683722 6218420 745024..746274 1 NC_010582.1 rod shape-determining protein RodA 746274 rodA 6218420 rodA Streptococcus pneumoniae CGSP14 rod shape-determining protein RodA YP_001835469.1 745024 D 516950 CDS YP_001835470.1 182683723 6216911 746285..746839 1 NC_010582.1 4-methyl-5(b-hydroxyethyl)-thiazole monophosphate biosynthesis protein 746839 thiJ 6216911 thiJ Streptococcus pneumoniae CGSP14 4-methyl-5(b-hydroxyethyl)-thiazole monophosphate biosynthesis protein YP_001835470.1 746285 D 516950 CDS YP_001835471.1 182683724 6217799 746915..747487 1 NC_010582.1 HAD superfamily hydrolase 747487 gph 6217799 gph Streptococcus pneumoniae CGSP14 HAD superfamily hydrolase YP_001835471.1 746915 D 516950 CDS YP_001835472.1 182683725 6216501 747502..749448 1 NC_010582.1 negatively supercoils closed circular double-stranded DNA; DNA gyrase subunit B 749448 gyrB 6216501 gyrB Streptococcus pneumoniae CGSP14 DNA gyrase subunit B YP_001835472.1 747502 D 516950 CDS YP_001835473.1 182683726 6217584 749503..751257 1 NC_010582.1 acts to negatively regulates ftsZ ring formation by modulating the frequency and position of the ftsZ ring formation; septation ring formation regulator EzrA 751257 ezrA 6217584 ezrA Streptococcus pneumoniae CGSP14 septation ring formation regulator EzrA YP_001835473.1 749503 D 516950 CDS YP_001835474.1 182683727 6216926 751788..751883 1 NC_010582.1 hypothetical protein 751883 6216926 SPCG_0757 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835474.1 751788 D 516950 CDS YP_001835475.1 182683728 6216640 complement(751981..752196) 1 NC_010582.1 IS66 family Orf2 752196 6216640 SPCG_0758 Streptococcus pneumoniae CGSP14 IS66 family Orf2 YP_001835475.1 751981 R 516950 CDS YP_001835476.1 182683729 6218423 complement(752564..752863) 1 NC_010582.1 hypothetical protein 752863 6218423 SPCG_0759 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835476.1 752564 R 516950 CDS YP_001835477.1 182683730 6218584 complement(753028..753492) 1 NC_010582.1 mutT/nudix family protein 753492 6218584 SPCG_0760 Streptococcus pneumoniae CGSP14 mutT/nudix family protein YP_001835477.1 753028 R 516950 CDS YP_001835478.1 182683731 6218294 753542..753958 1 NC_010582.1 IS630-Spn1, transposase Orf1 753958 6218294 SPCG_0761 Streptococcus pneumoniae CGSP14 IS630-Spn1, transposase Orf1 YP_001835478.1 753542 D 516950 CDS YP_001835479.1 182683732 6217814 complement(754612..756870) 1 NC_010582.1 ATP-dependent Clp protease, ATP-binding subunit ClpE 756870 clpE 6217814 clpE Streptococcus pneumoniae CGSP14 ATP-dependent Clp protease, ATP-binding subunit ClpE YP_001835479.1 754612 R 516950 CDS YP_001835480.1 182683733 6218237 complement(757099..757329) 1 NC_010582.1 hypothetical protein 757329 6218237 SPCG_0763 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835480.1 757099 R 516950 CDS YP_001835481.1 182683734 6218145 757513..758202 1 NC_010582.1 amino acid ABC transporter permease 758202 6218145 SPCG_0764 Streptococcus pneumoniae CGSP14 amino acid ABC transporter permease YP_001835481.1 757513 D 516950 CDS YP_001835482.1 182683735 6216922 758202..758936 1 NC_010582.1 amino acid ABC transporter ATP-binding protein 758936 6216922 SPCG_0765 Streptococcus pneumoniae CGSP14 amino acid ABC transporter ATP-binding protein YP_001835482.1 758202 D 516950 CDS YP_001835483.1 182683736 6217152 759027..759947 1 NC_010582.1 catalyzes the formation of 5,10-methenyltetrahydrofolate from 5,10-methylenetetrahydrofolate and subsequent formation of 10-formyltetrahydrofolate from 5,10-methenyltetrahydrofolate; bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase 759947 6217152 SPCG_0766 Streptococcus pneumoniae CGSP14 bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase YP_001835483.1 759027 D 516950 CDS YP_001835484.1 182683737 6217945 760085..760906 1 NC_010582.1 hypothetical protein 760906 6217945 SPCG_0767 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835484.1 760085 D 516950 CDS YP_001835485.1 182683738 6217526 760921..761793 1 NC_010582.1 hypothetical protein 761793 6217526 SPCG_0768 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835485.1 760921 D 516950 CDS YP_001835486.1 182683739 6216738 complement(761790..761915) 1 NC_010582.1 hypothetical protein 761915 6216738 SPCG_0769 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835486.1 761790 R 516950 CDS YP_001835487.1 182683740 6217933 762018..762758 1 NC_010582.1 Catalyzes D-ribose 5-phosphate --> D-ribulose 5-phosphate in the nonoxidative branch of the pentose phosphate pathway; ribose-5-phosphate isomerase A 762758 rpiA 6217933 rpiA Streptococcus pneumoniae CGSP14 ribose-5-phosphate isomerase A YP_001835487.1 762018 D 516950 CDS YP_001835488.1 182683741 6216458 762709..763983 1 NC_010582.1 catalyzes the transfer of phosphate between the C1 and C5 carbons of pentose; phosphopentomutase 763983 deoB 6216458 deoB Streptococcus pneumoniae CGSP14 phosphopentomutase YP_001835488.1 762709 D 516950 CDS YP_001835489.1 182683742 6216589 763985..764158 1 NC_010582.1 hypothetical protein 764158 6216589 SPCG_0772 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835489.1 763985 D 516950 CDS YP_001835490.1 182683743 6216746 764273..764542 1 NC_010582.1 hypothetical protein 764542 6216746 SPCG_0773 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835490.1 764273 D 516950 CDS YP_001835491.1 182683744 6217022 764542..765351 1 NC_010582.1 catalyzes the formation of a purine and ribose phosphate from a purine nucleoside; in E. coli this enzyme functions in xanthosine degradation; purine nucleoside phosphorylase 765351 pnp 6217022 pnp Streptococcus pneumoniae CGSP14 purine nucleoside phosphorylase YP_001835491.1 764542 D 516950 CDS YP_001835492.1 182683745 6216700 765815..766222 1 NC_010582.1 hypothetical protein 766222 6216700 SPCG_0775 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835492.1 765815 D 516950 CDS YP_001835493.1 182683746 6217430 766232..766807 1 NC_010582.1 hypothetical protein 766807 6217430 SPCG_0776 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835493.1 766232 D 516950 CDS YP_001835494.1 182683747 6218330 766832..767344 1 NC_010582.1 hemolysin-like protein 767344 6218330 SPCG_0777 Streptococcus pneumoniae CGSP14 hemolysin-like protein YP_001835494.1 766832 D 516950 CDS YP_001835495.1 182683748 6216751 768002..768712 1 NC_010582.1 catalyzes the reversible phosphorolysis of ribonucleosides and 2'- deoxyribonucleosides to the free base and (2'-deoxy)ribose-1- phosphate; purine nucleoside phosphorylase 768712 deoD 6216751 deoD Streptococcus pneumoniae CGSP14 purine nucleoside phosphorylase YP_001835495.1 768002 D 516950 CDS YP_001835496.1 182683749 6217973 complement(768735..769259) 1 NC_010582.1 topology modulation protein 769259 flaR 6217973 flaR Streptococcus pneumoniae CGSP14 topology modulation protein YP_001835496.1 768735 R 516950 CDS YP_001835497.1 182683750 6216796 complement(769312..769563) 1 NC_010582.1 binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase; 30S ribosomal protein S20 769563 rpsT 6216796 rpsT Streptococcus pneumoniae CGSP14 30S ribosomal protein S20 YP_001835497.1 769312 R 516950 CDS YP_001835498.1 182683751 6217727 complement(769616..770566) 1 NC_010582.1 catalyzes the formation of (R)-4'-phosphopantothenate in coenzyme A biosynthesis; pantothenate kinase 770566 coaA 6217727 coaA Streptococcus pneumoniae CGSP14 pantothenate kinase YP_001835498.1 769616 R 516950 CDS YP_001835499.1 182683752 6216587 770726..771130 1 NC_010582.1 hypothetical protein 771130 6216587 SPCG_0782 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835499.1 770726 D 516950 CDS YP_001835500.1 182683753 6218088 771337..771927 1 NC_010582.1 hypothetical protein 771927 6218088 SPCG_0783 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835500.1 771337 D 516950 CDS YP_001835501.1 182683754 6218084 771924..773201 1 NC_010582.1 Catalyzes the reversible phosphorolysis of pyrimidines in the nucleotide synthesis salvage pathway; pyrimidine-nucleoside phosphorylase 773201 pdp 6218084 pdp Streptococcus pneumoniae CGSP14 pyrimidine-nucleoside phosphorylase YP_001835501.1 771924 D 516950 CDS YP_001835502.1 182683755 6216427 773219..773881 1 NC_010582.1 catalyzes the formation of D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-D-ribose-5-phosphate; deoxyribose-phosphate aldolase 773881 deoC 6216427 deoC Streptococcus pneumoniae CGSP14 deoxyribose-phosphate aldolase YP_001835502.1 773219 D 516950 CDS YP_001835503.1 182683756 6217976 773868..774257 1 NC_010582.1 Reclaims exogenous and endogenous cytidine and 2'-deoxycytidine molecules for UMP synthesis; cytidine deaminase 774257 cdd 6217976 cdd Streptococcus pneumoniae CGSP14 cytidine deaminase YP_001835503.1 773868 D 516950 CDS YP_001835504.1 182683757 6217774 774275..775399 1 NC_010582.1 lipoprotein 775399 6217774 SPCG_0787 Streptococcus pneumoniae CGSP14 lipoprotein YP_001835504.1 774275 D 516950 CDS YP_001835505.1 182683758 6217380 775543..777078 1 NC_010582.1 sugar ABC transporter ATP-binding protein 777078 6217380 SPCG_0788 Streptococcus pneumoniae CGSP14 sugar ABC transporter ATP-binding protein YP_001835505.1 775543 D 516950 CDS YP_001835506.1 182683759 6216533 777044..778129 1 NC_010582.1 sugar ABC transporter permease 778129 6216533 SPCG_0789 Streptococcus pneumoniae CGSP14 sugar ABC transporter permease YP_001835506.1 777044 D 516950 CDS YP_001835507.1 182683760 6217614 778132..779088 1 NC_010582.1 sugar ABC transporter permease 779088 6217614 SPCG_0790 Streptococcus pneumoniae CGSP14 sugar ABC transporter permease YP_001835507.1 778132 D 516950 CDS YP_001835508.1 182683761 6216873 779173..779385 1 NC_010582.1 degenerate transposase 779385 6216873 SPCG_0791 Streptococcus pneumoniae CGSP14 degenerate transposase YP_001835508.1 779173 D 516950 CDS YP_001835509.1 182683762 6217146 779521..779688 1 NC_010582.1 hypothetical protein 779688 6217146 SPCG_0792 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835509.1 779521 D 516950 CDS YP_001835510.1 182683763 6218345 779688..779960 1 NC_010582.1 degenerate transposase 779960 6218345 SPCG_0793 Streptococcus pneumoniae CGSP14 degenerate transposase YP_001835510.1 779688 D 516950 CDS YP_001835511.1 182683764 6216592 780022..780510 1 NC_010582.1 degenerate transposase 780510 6216592 SPCG_0794 Streptococcus pneumoniae CGSP14 degenerate transposase YP_001835511.1 780022 D 516950 CDS YP_001835512.1 182683765 6216890 complement(780553..781194) 1 NC_010582.1 involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsX; glycerol-3-phosphate acyltransferase PlsY 781194 6216890 SPCG_0795 Streptococcus pneumoniae CGSP14 glycerol-3-phosphate acyltransferase PlsY YP_001835512.1 780553 R 516950 CDS YP_001835513.1 182683766 6217743 781330..783273 1 NC_010582.1 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling; DNA topoisomerase IV subunit B 783273 parE 6217743 parE Streptococcus pneumoniae CGSP14 DNA topoisomerase IV subunit B YP_001835513.1 781330 D 516950 CDS YP_001835514.1 182683767 6218463 783273..783380 1 NC_010582.1 hypothetical protein 783380 6218463 SPCG_0797 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835514.1 783273 D 516950 CDS YP_001835515.1 182683768 6216352 783394..783519 1 NC_010582.1 hypothetical protein 783519 6216352 SPCG_0798 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835515.1 783394 D 516950 CDS YP_001835516.1 182683769 6216634 783684..786164 1 NC_010582.1 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling; DNA topoisomerase IV subunit A 786164 parC 6216634 parC Streptococcus pneumoniae CGSP14 DNA topoisomerase IV subunit A YP_001835516.1 783684 D 516950 CDS YP_001835517.1 182683770 6217796 786296..787318 1 NC_010582.1 catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids; branched-chain amino acid aminotransferase 787318 ilvE 6217796 ilvE Streptococcus pneumoniae CGSP14 branched-chain amino acid aminotransferase YP_001835517.1 786296 D 516950 CDS YP_001835518.1 182683771 6217323 787374..788078 1 NC_010582.1 peptide ABC transporter periplasmic protein 788078 6217323 SPCG_0801 Streptococcus pneumoniae CGSP14 peptide ABC transporter periplasmic protein YP_001835518.1 787374 D 516950 CDS YP_001835519.1 182683772 6216489 788122..788832 1 NC_010582.1 hypothetical protein 788832 6216489 SPCG_0802 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835519.1 788122 D 516950 CDS YP_001835520.1 182683773 6217151 788829..789752 1 NC_010582.1 membrane protein 789752 6217151 SPCG_0803 Streptococcus pneumoniae CGSP14 membrane protein YP_001835520.1 788829 D 516950 CDS YP_001835521.1 182683774 6216696 789767..790411 1 NC_010582.1 catalyzes the removal of 5-oxoproline from various penultimate amino acid residues except L-proline; pyrrolidone-carboxylate peptidase 790411 pcp 6216696 pcp Streptococcus pneumoniae CGSP14 pyrrolidone-carboxylate peptidase YP_001835521.1 789767 D 516950 CDS YP_001835522.1 182683775 6218442 790579..790809 1 NC_010582.1 hypothetical protein 790809 6218442 SPCG_0805 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835522.1 790579 D 516950 CDS YP_001835523.1 182683776 6216442 791182..792384 1 NC_010582.1 in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins; 30S ribosomal protein S1 792384 rpsA 6216442 rpsA Streptococcus pneumoniae CGSP14 30S ribosomal protein S1 YP_001835523.1 791182 D 516950 CDS YP_001835524.1 182683777 6217287 complement(792469..792972) 1 NC_010582.1 degenerate transposase 792972 6217287 SPCG_0807 Streptococcus pneumoniae CGSP14 degenerate transposase YP_001835524.1 792469 R 516950 CDS YP_001835525.1 182683778 6217755 complement(793253..793624) 1 NC_010582.1 degenerate transposase 793624 6217755 SPCG_0808 Streptococcus pneumoniae CGSP14 degenerate transposase YP_001835525.1 793253 R 516950 CDS YP_001835526.1 182683779 6217103 793964..794461 1 NC_010582.1 hypothetical protein 794461 6217103 SPCG_0809 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835526.1 793964 D 516950 CDS YP_001835527.1 182683780 6217979 794461..796116 1 NC_010582.1 catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the tau chain serves as a scaffold to help in the dimerizaton of the alpha,epsilon and theta core complex; the gamma chain seems to interact with the delta and delta' subunits to transfer the beta subunit on the DNA; DNA polymerase III subunits gamma and tau 796116 dnaX 6217979 dnaX Streptococcus pneumoniae CGSP14 DNA polymerase III subunits gamma and tau YP_001835527.1 794461 D 516950 CDS YP_001835528.1 182683781 6217620 796144..796338 1 NC_010582.1 hypothetical protein 796338 6217620 SPCG_0811 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835528.1 796144 D 516950 CDS YP_001835529.1 182683782 6217663 796467..797258 1 NC_010582.1 ABC transporter ATP-binding protein 797258 6217663 SPCG_0812 Streptococcus pneumoniae CGSP14 ABC transporter ATP-binding protein YP_001835529.1 796467 D 516950 CDS YP_001835530.1 182683783 6218282 797286..798548 1 NC_010582.1 hypothetical protein 798548 6218282 SPCG_0813 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835530.1 797286 D 516950 CDS YP_001835531.1 182683784 6216536 798514..799785 1 NC_010582.1 class-V aminotransferase 799785 6216536 SPCG_0814 Streptococcus pneumoniae CGSP14 class-V aminotransferase YP_001835531.1 798514 D 516950 CDS YP_001835532.1 182683785 6216766 799742..800212 1 NC_010582.1 nifU family protein 800212 nifU 6216766 nifU Streptococcus pneumoniae CGSP14 nifU family protein YP_001835532.1 799742 D 516950 CDS YP_001835533.1 182683786 6218313 800266..801678 1 NC_010582.1 FeS assembly protein SufB 801678 6218313 SPCG_0816 Streptococcus pneumoniae CGSP14 FeS assembly protein SufB YP_001835533.1 800266 D 516950 CDS YP_001835534.1 182683787 6218357 complement(801909..803150) 1 NC_010582.1 D-alanyl-D-alanine carboxypeptidase 803150 dacA 6218357 dacA Streptococcus pneumoniae CGSP14 D-alanyl-D-alanine carboxypeptidase YP_001835534.1 801909 R 516950 CDS YP_001835535.1 182683788 6218334 803253..804362 1 NC_010582.1 membrane protein 804362 6218334 SPCG_0818 Streptococcus pneumoniae CGSP14 membrane protein YP_001835535.1 803253 D 516950 CDS YP_001835536.1 182683789 6218351 complement(805241..805348) 1 NC_010582.1 hypothetical protein 805348 6218351 SPCG_0819 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835536.1 805241 R 516950 CDS YP_001835537.1 182683790 6218133 complement(805487..806263) 1 NC_010582.1 hypothetical protein 806263 6218133 SPCG_0820 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835537.1 805487 R 516950 CDS YP_001835538.1 182683791 6217091 complement(806290..806760) 1 NC_010582.1 hypothetical protein 806760 6217091 SPCG_0821 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835538.1 806290 R 516950 CDS YP_001835539.1 182683792 6217084 complement(806815..807279) 1 NC_010582.1 hypothetical protein 807279 6217084 SPCG_0822 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835539.1 806815 R 516950 CDS YP_001835540.1 182683793 6218062 807327..807434 1 NC_010582.1 hypothetical protein 807434 6218062 SPCG_0823 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835540.1 807327 D 516950 CDS YP_001835541.1 182683794 6216732 807884..808624 1 NC_010582.1 lactose phosphotransferase system repressor 808624 fruR 6216732 fruR Streptococcus pneumoniae CGSP14 lactose phosphotransferase system repressor YP_001835541.1 807884 D 516950 CDS YP_001835542.1 182683795 6216550 808621..809532 1 NC_010582.1 1-phosphofructokinase 809532 fruB 6216550 fruB Streptococcus pneumoniae CGSP14 1-phosphofructokinase YP_001835542.1 808621 D 516950 CDS YP_001835543.1 182683796 6217632 809529..811481 1 NC_010582.1 PTS system fructose specific transporter subunit IIABC 811481 fruA 6217632 fruA Streptococcus pneumoniae CGSP14 PTS system fructose specific transporter subunit IIABC YP_001835543.1 809529 D 516950 CDS YP_001835544.1 182683797 6216770 811567..813870 1 NC_010582.1 spoE family protein 813870 ftsK 6216770 ftsK Streptococcus pneumoniae CGSP14 spoE family protein YP_001835544.1 811567 D 516950 CDS YP_001835545.1 182683799 6216858 complement(813915..814448) 1 NC_010582.1 hypothetical protein 814448 6216858 SPCG_0828 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835545.1 813915 R 516950 CDS YP_001835546.1 182683798 6218109 814421..815623 1 NC_010582.1 class-V aminotransferase 815623 6218109 SPCG_0829 Streptococcus pneumoniae CGSP14 class-V aminotransferase YP_001835546.1 814421 D 516950 CDS YP_001835547.1 182683800 6218272 815632..816846 1 NC_010582.1 Required for the synthesis of the thiazole moiety; thiamine biosynthesis protein ThiI 816846 thiI 6218272 thiI Streptococcus pneumoniae CGSP14 thiamine biosynthesis protein ThiI YP_001835547.1 815632 D 516950 CDS YP_001835548.1 182683801 6216623 816957..817805 1 NC_010582.1 hypothetical protein 817805 6216623 SPCG_0831 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835548.1 816957 D 516950 CDS YP_001835549.1 182683802 6217162 817827..818162 1 NC_010582.1 hypothetical protein 818162 6217162 SPCG_0832 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835549.1 817827 D 516950 CDS YP_001835550.1 182683803 6217378 818159..818566 1 NC_010582.1 hypothetical protein 818566 6217378 SPCG_0833 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835550.1 818159 D 516950 CDS YP_001835551.1 182683804 6218037 818579..819745 1 NC_010582.1 hypothetical protein 819745 6218037 SPCG_0834 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835551.1 818579 D 516950 CDS YP_001835552.1 182683805 6216456 820253..821746 1 NC_010582.1 type I restriction-modification system, M subunit 821746 6216456 SPCG_0835 Streptococcus pneumoniae CGSP14 type I restriction-modification system, M subunit YP_001835552.1 820253 D 516950 CDS YP_001835553.1 182683806 6216388 821759..822301 1 NC_010582.1 type I restriction-modification system subunit S 822301 6216388 SPCG_0836 Streptococcus pneumoniae CGSP14 type I restriction-modification system subunit S YP_001835553.1 821759 D 516950 CDS YP_001835554.1 182683807 6217549 822298..823416 1 NC_010582.1 type I restriction-modification system subunit S 823416 6217549 SPCG_0837 Streptococcus pneumoniae CGSP14 type I restriction-modification system subunit S YP_001835554.1 822298 D 516950 CDS YP_001835555.1 182683808 6216614 823476..823712 1 NC_010582.1 hypothetical protein 823712 6216614 SPCG_0838 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835555.1 823476 D 516950 CDS YP_001835556.1 182683809 6216861 823709..824122 1 NC_010582.1 hypothetical protein 824122 6216861 SPCG_0839 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835556.1 823709 D 516950 CDS YP_001835557.1 182683810 6217210 824240..825205 1 NC_010582.1 phage integrase family integrase/recombinase 825205 6217210 SPCG_0840 Streptococcus pneumoniae CGSP14 phage integrase family integrase/recombinase YP_001835557.1 824240 D 516950 CDS YP_001835558.1 182683811 6217053 825150..825809 1 NC_010582.1 type I restriction-modification system subunit S 825809 6217053 SPCG_0841 Streptococcus pneumoniae CGSP14 type I restriction-modification system subunit S YP_001835558.1 825150 D 516950 CDS YP_001835559.1 182683812 6216644 825839..829189 1 NC_010582.1 type I restriction-modification system, R subunit 829189 6216644 SPCG_0842 Streptococcus pneumoniae CGSP14 type I restriction-modification system, R subunit YP_001835559.1 825839 D 516950 CDS YP_001835560.1 182683813 6216857 complement(829589..831169) 1 NC_010582.1 IS1380-Spn1 transposase 831169 6216857 SPCG_0843 Streptococcus pneumoniae CGSP14 IS1380-Spn1 transposase YP_001835560.1 829589 R 516950 CDS YP_001835561.1 182683814 6217080 831169..831369 1 NC_010582.1 hypothetical protein 831369 6217080 SPCG_0844 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835561.1 831169 D 516950 CDS YP_001835562.1 182683815 6217279 complement(831571..831846) 1 NC_010582.1 degenerate transposase 831846 6217279 SPCG_0845 Streptococcus pneumoniae CGSP14 degenerate transposase YP_001835562.1 831571 R 516950 CDS YP_001835563.1 182683816 6217150 831902..832045 1 NC_010582.1 hypothetical protein 832045 6217150 SPCG_0846 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835563.1 831902 D 516950 CDS YP_001835564.1 182683817 6218556 832138..832725 1 NC_010582.1 hypothetical protein 832725 6218556 SPCG_0847 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835564.1 832138 D 516950 CDS YP_001835565.1 182683818 6218366 833123..833932 1 NC_010582.1 phosphosugar-binding transcriptional regulator 833932 6218366 SPCG_0848 Streptococcus pneumoniae CGSP14 phosphosugar-binding transcriptional regulator YP_001835565.1 833123 D 516950 CDS YP_001835566.1 182683819 6217592 833937..834638 1 NC_010582.1 Converts N-acetylmannosamine-6-phosphate to N-acetylglucosamine-6-phosphate; N-acetylmannosamine-6-phosphate 2-epimerase 834638 6217592 SPCG_0849 Streptococcus pneumoniae CGSP14 N-acetylmannosamine-6-phosphate 2-epimerase YP_001835566.1 833937 D 516950 CDS YP_001835567.1 182683820 6217271 834663..835580 1 NC_010582.1 N-acetylneuraminate lyase 835580 6217271 SPCG_0850 Streptococcus pneumoniae CGSP14 N-acetylneuraminate lyase YP_001835567.1 834663 D 516950 CDS YP_001835568.1 182683821 6216650 835608..837149 1 NC_010582.1 sodium:solute symporter family protein 837149 6216650 SPCG_0851 Streptococcus pneumoniae CGSP14 sodium:solute symporter family protein YP_001835568.1 835608 D 516950 CDS YP_001835569.1 182683822 6216652 837168..837626 1 NC_010582.1 hypothetical protein 837626 6216652 SPCG_0852 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835569.1 837168 D 516950 CDS YP_001835570.1 182683823 6216534 837628..839850 1 NC_010582.1 neuraminidase 839850 nanC 6216534 nanC Streptococcus pneumoniae CGSP14 neuraminidase YP_001835570.1 837628 D 516950 CDS YP_001835571.1 182683824 6217504 839860..840999 1 NC_010582.1 Gfo/Idh/MocA family oxidoreductase 840999 6217504 SPCG_0854 Streptococcus pneumoniae CGSP14 Gfo/Idh/MocA family oxidoreductase YP_001835571.1 839860 D 516950 CDS YP_001835572.1 182683825 6216931 841156..842046 1 NC_010582.1 ROK family protein 842046 6216931 SPCG_0855 Streptococcus pneumoniae CGSP14 ROK family protein YP_001835572.1 841156 D 516950 CDS YP_001835573.1 182683826 6217062 842071..842394 1 NC_010582.1 hypothetical protein 842394 6217062 SPCG_0856 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835573.1 842071 D 516950 CDS YP_001835574.1 182683827 6218484 842384..844375 1 NC_010582.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit I is part of the membrane proton channel.; V-type ATP synthase subunit I 844375 6218484 SPCG_0857 Streptococcus pneumoniae CGSP14 V-type ATP synthase subunit I YP_001835574.1 842384 D 516950 CDS YP_001835575.1 182683828 6217783 844391..844867 1 NC_010582.1 produces ATP from ADP in the presence of a proton gradient across the membrane; the K subunit is a nonenzymatic component which binds the dimeric form by interacting with the G and E subunits; V-type ATP synthase subunit K 844867 6217783 SPCG_0858 Streptococcus pneumoniae CGSP14 V-type ATP synthase subunit K YP_001835575.1 844391 D 516950 CDS YP_001835576.1 182683829 6217874 844901..845482 1 NC_010582.1 v-type sodium ATP synthase subunit E 845482 6217874 SPCG_0859 Streptococcus pneumoniae CGSP14 v-type sodium ATP synthase subunit E YP_001835576.1 844901 D 516950 CDS YP_001835577.1 182683830 6216499 845547..846554 1 NC_010582.1 v-type sodium ATP synthase subunit C 846554 6216499 SPCG_0860 Streptococcus pneumoniae CGSP14 v-type sodium ATP synthase subunit C YP_001835577.1 845547 D 516950 CDS YP_001835578.1 182683831 6217258 846544..846864 1 NC_010582.1 produces ATP from ADP in the presence of a proton gradient across the membrane; the F subunit is part of the catalytic core of the ATP synthase complex; V-type ATP synthase subunit F 846864 6217258 SPCG_0861 Streptococcus pneumoniae CGSP14 V-type ATP synthase subunit F YP_001835578.1 846544 D 516950 CDS YP_001835579.1 182683832 6218341 846903..848702 1 NC_010582.1 produces ATP from ADP in the presence of a proton gradient across the membrane; the A subunit is part of the catalytic core of the ATP synthase complex; V-type ATP synthase subunit A 848702 6218341 SPCG_0862 Streptococcus pneumoniae CGSP14 V-type ATP synthase subunit A YP_001835579.1 846903 D 516950 CDS YP_001835580.1 182683833 6217447 848703..850088 1 NC_010582.1 produces ATP from ADP in the presence of a proton gradient across the membrane; the B subunit is part of the catalytic core of the ATP synthase complex; V-type ATP synthase subunit B 850088 6217447 SPCG_0863 Streptococcus pneumoniae CGSP14 V-type ATP synthase subunit B YP_001835580.1 848703 D 516950 CDS YP_001835581.1 182683834 6217215 850111..850722 1 NC_010582.1 produces ATP from ADP in the presence of a proton gradient across the membrane; the D subunit is part of the catalytic core of the ATP synthase complex; V-type ATP synthase subunit D 850722 6217215 SPCG_0864 Streptococcus pneumoniae CGSP14 V-type ATP synthase subunit D YP_001835581.1 850111 D 516950 CDS YP_001835582.1 182683835 6217244 complement(850832..851359) 1 NC_010582.1 degenerate transposase 851359 6217244 SPCG_0865 Streptococcus pneumoniae CGSP14 degenerate transposase YP_001835582.1 850832 R 516950 CDS YP_001835583.1 182683836 6218310 complement(851640..852158) 1 NC_010582.1 degenerate transposase 852158 6218310 SPCG_0866 Streptococcus pneumoniae CGSP14 degenerate transposase YP_001835583.1 851640 R 516950 CDS YP_001835584.1 182683837 6218388 852291..852458 1 NC_010582.1 hypothetical protein 852458 6218388 SPCG_0867 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835584.1 852291 D 516950 CDS YP_001835585.1 182683838 6217111 852474..852734 1 NC_010582.1 hypothetical protein 852734 6217111 SPCG_0868 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835585.1 852474 D 516950 CDS YP_001835586.1 182683839 6218325 complement(852838..853308) 1 NC_010582.1 transcriptional repressor 853308 6218325 SPCG_0869 Streptococcus pneumoniae CGSP14 transcriptional repressor YP_001835586.1 852838 R 516950 CDS YP_001835587.1 182683840 6217579 complement(853325..855598) 1 NC_010582.1 catalyzes the removal of N-terminal dipeptides when proline is the penultimate residue; x-prolyl-dipeptidyl aminopeptidase 855598 6217579 SPCG_0870 Streptococcus pneumoniae CGSP14 x-prolyl-dipeptidyl aminopeptidase YP_001835587.1 853325 R 516950 CDS YP_001835588.1 182683841 6218323 855918..859046 1 NC_010582.1 Catalyzes DNA-template-directed extension of the 3'-end of a DNA strand by one nucleotide at a time. Proposed to be responsible for the synthesis of the lagging strand. In the low GC gram positive bacteria this enzyme is less processive and more error prone than its counterpart in other bacteria.; DNA polymerase III DnaE 859046 dnaE 6218323 dnaE Streptococcus pneumoniae CGSP14 DNA polymerase III DnaE YP_001835588.1 855918 D 516950 CDS YP_001835589.1 182683842 6218307 859129..860136 1 NC_010582.1 catalyzes the formation of D-fructose 1,6-bisphosphate from D-fructose 6-phosphate in glycolysis; 6-phosphofructokinase 860136 pfkA 6218307 pfkA Streptococcus pneumoniae CGSP14 6-phosphofructokinase YP_001835589.1 859129 D 516950 CDS YP_001835590.1 182683843 6218444 860195..861700 1 NC_010582.1 catalyzes the formation of phosphoenolpyruvate from pyruvate; pyruvate kinase 861700 6218444 SPCG_0873 Streptococcus pneumoniae CGSP14 pyruvate kinase YP_001835590.1 860195 D 516950 CDS YP_001835591.1 182683844 6218324 complement(862864..863082) 1 NC_010582.1 hypothetical protein 863082 6218324 SPCG_0874 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835591.1 862864 R 516950 CDS YP_001835592.1 182683845 6218289 863518..864390 1 NC_010582.1 hypothetical protein 864390 6218289 SPCG_0875 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835592.1 863518 D 516950 CDS YP_001835593.1 182683846 6216726 864403..864567 1 NC_010582.1 hypothetical protein 864567 6216726 SPCG_0876 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835593.1 864403 D 516950 CDS YP_001835594.1 182683847 6218349 864488..864580 1 NC_010582.1 hypothetical protein 864580 6218349 SPCG_0877 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835594.1 864488 D 516950 CDS YP_001835595.1 182683848 6217070 complement(864497..864880) 1 NC_010582.1 IS1381 transposase protein A 864880 6217070 SPCG_0878 Streptococcus pneumoniae CGSP14 IS1381 transposase protein A YP_001835595.1 864497 R 516950 CDS YP_001835596.1 182683849 6217335 865023..865334 1 NC_010582.1 hypothetical protein 865334 6217335 SPCG_0879 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835596.1 865023 D 516950 CDS YP_001835597.1 182683850 6217114 865338..866054 1 NC_010582.1 hypothetical protein 866054 6217114 SPCG_0880 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835597.1 865338 D 516950 CDS YP_001835598.1 182683851 6216756 complement(866184..866999) 1 NC_010582.1 hypothetical protein 866999 6216756 SPCG_0881 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835598.1 866184 R 516950 CDS YP_001835599.1 182683852 6216908 complement(866996..867901) 1 NC_010582.1 hypothetical protein 867901 6216908 SPCG_0882 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835599.1 866996 R 516950 CDS YP_001835600.1 182683853 6217596 complement(867902..868033) 1 NC_010582.1 hypothetical protein 868033 6217596 SPCG_0883 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835600.1 867902 R 516950 CDS YP_001835601.1 182683854 6217379 868243..869610 1 NC_010582.1 capsular polysaccharide biosynthesis protein 869610 6217379 SPCG_0884 Streptococcus pneumoniae CGSP14 capsular polysaccharide biosynthesis protein YP_001835601.1 868243 D 516950 CDS YP_001835602.1 182683855 6218091 869694..871841 1 NC_010582.1 transcriptional regulator 871841 6218091 SPCG_0885 Streptococcus pneumoniae CGSP14 transcriptional regulator YP_001835602.1 869694 D 516950 CDS YP_001835603.1 182683856 6216511 871828..872277 1 NC_010582.1 hypothetical protein 872277 6216511 SPCG_0886 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835603.1 871828 D 516950 CDS YP_001835604.1 182683857 6218103 872335..872607 1 NC_010582.1 hypothetical protein 872607 6218103 SPCG_0887 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835604.1 872335 D 516950 CDS YP_001835605.1 182683858 6217934 complement(872655..872819) 1 NC_010582.1 hypothetical protein 872819 6217934 SPCG_0888 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835605.1 872655 R 516950 CDS YP_001835606.1 182683859 6218270 873523..874338 1 NC_010582.1 ABC transporter ATP-binding protein 874338 6218270 SPCG_0889 Streptococcus pneumoniae CGSP14 ABC transporter ATP-binding protein YP_001835606.1 873523 D 516950 CDS YP_001835607.1 182683860 6216523 874340..876328 1 NC_010582.1 ABC transporter permease 876328 6216523 SPCG_0890 Streptococcus pneumoniae CGSP14 ABC transporter permease YP_001835607.1 874340 D 516950 CDS YP_001835608.1 182683861 6216524 complement(876370..876960) 1 NC_010582.1 membrane protein 876960 6216524 SPCG_0891 Streptococcus pneumoniae CGSP14 membrane protein YP_001835608.1 876370 R 516950 CDS YP_001835609.1 182683862 6218368 complement(877040..877960) 1 NC_010582.1 IS1239 transposase 877960 6218368 SPCG_0892 Streptococcus pneumoniae CGSP14 IS1239 transposase YP_001835609.1 877040 R 516950 CDS YP_001835610.1 182683863 6218353 878622..880097 1 NC_010582.1 lysine decarboxylase 880097 cad 6218353 cad Streptococcus pneumoniae CGSP14 lysine decarboxylase YP_001835610.1 878622 D 516950 CDS YP_001835611.1 182683864 6218342 complement(880063..880533) 1 NC_010582.1 pilin gene inverting-like protein,truncated 880533 6218342 SPCG_0894 Streptococcus pneumoniae CGSP14 pilin gene inverting-like protein,truncated YP_001835611.1 880063 R 516950 CDS YP_001835612.1 182683865 6217110 881034..881894 1 NC_010582.1 catalyzes the formation of spermidine from putrescine and S-adenosylmethioninamine; spermidine synthase 881894 speE 6217110 speE Streptococcus pneumoniae CGSP14 spermidine synthase YP_001835612.1 881034 D 516950 CDS YP_001835613.1 182683866 6218309 881891..883150 1 NC_010582.1 hypothetical protein 883150 6218309 SPCG_0896 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835613.1 881891 D 516950 CDS YP_001835614.1 182683867 6218538 883150..884277 1 NC_010582.1 carboxynorspermidine decarboxylase 884277 nspC 6218538 nspC Streptococcus pneumoniae CGSP14 carboxynorspermidine decarboxylase YP_001835614.1 883150 D 516950 CDS YP_001835615.1 182683868 6218316 884274..885359 1 NC_010582.1 catalyzes the formation of carbamoylputrescine from agmatine in the arginine decarboxylase pathway of putrescine biosynthesis; agmatine deiminase 885359 6218316 SPCG_0898 Streptococcus pneumoniae CGSP14 agmatine deiminase YP_001835615.1 884274 D 516950 CDS YP_001835616.1 182683869 6218315 885369..886244 1 NC_010582.1 carbon-nitrogen hydrolase family protein 886244 6218315 SPCG_0899 Streptococcus pneumoniae CGSP14 carbon-nitrogen hydrolase family protein YP_001835616.1 885369 D 516950 CDS YP_001835617.1 182683870 6217633 complement(886425..887234) 1 NC_010582.1 Cof family protein 887234 6217633 SPCG_0900 Streptococcus pneumoniae CGSP14 Cof family protein YP_001835617.1 886425 R 516950 CDS YP_001835618.1 182683871 6216526 887781..888452 1 NC_010582.1 hypothetical protein 888452 6216526 SPCG_0901 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835618.1 887781 D 516950 CDS YP_001835619.1 182683872 6217400 888694..889602 1 NC_010582.1 LysR family transcriptional regulator 889602 cpsY 6217400 cpsY Streptococcus pneumoniae CGSP14 LysR family transcriptional regulator YP_001835619.1 888694 D 516950 CDS YP_001835620.1 182683873 6218545 889599..890060 1 NC_010582.1 lipoprotein signal peptidase; integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis; lipoprotein signal peptidase 890060 lspA 6218545 lspA Streptococcus pneumoniae CGSP14 lipoprotein signal peptidase YP_001835620.1 889599 D 516950 CDS YP_001835621.1 182683874 6216935 890050..890937 1 NC_010582.1 ribosomal large subunit pseudouridine synthase D 890937 rluD 6216935 rluD Streptococcus pneumoniae CGSP14 ribosomal large subunit pseudouridine synthase D YP_001835621.1 890050 D 516950 CDS YP_001835622.1 182683875 6217197 890940..892823 1 NC_010582.1 choline binding protein E 892823 lytD 6217197 lytD Streptococcus pneumoniae CGSP14 choline binding protein E YP_001835622.1 890940 D 516950 CDS YP_001835623.1 182683876 6218518 892903..894033 1 NC_010582.1 catalyzes the formation of glutamate 5-phosphate from glutamate in proline biosynthesis; gamma-glutamyl kinase 894033 proB 6218518 proB Streptococcus pneumoniae CGSP14 gamma-glutamyl kinase YP_001835623.1 892903 D 516950 CDS YP_001835624.1 182683877 6216938 894043..895305 1 NC_010582.1 Catalyzes the phosphorylation of L-glutamate during the proline biosynthesis pathway; gamma-glutamyl phosphate reductase 895305 proA 6216938 proA Streptococcus pneumoniae CGSP14 gamma-glutamyl phosphate reductase YP_001835624.1 894043 D 516950 CDS YP_001835625.1 182683878 6218490 895309..896106 1 NC_010582.1 pyrroline-5-carboxylate reductase 896106 proC 6218490 proC Streptococcus pneumoniae CGSP14 pyrroline-5-carboxylate reductase YP_001835625.1 895309 D 516950 CDS YP_001835626.1 182683879 6217554 896326..896964 1 NC_010582.1 catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to thymidine monophosphate (dTMP) to form thymidine diphosphate (dTDP); thymidylate kinase 896964 tmk 6217554 tmk Streptococcus pneumoniae CGSP14 thymidylate kinase YP_001835626.1 896326 D 516950 CDS YP_001835627.1 182683880 6216527 896961..897851 1 NC_010582.1 catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the delta' subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA.; DNA polymerase III subunit delta' 897851 holB 6216527 holB Streptococcus pneumoniae CGSP14 DNA polymerase III subunit delta' YP_001835627.1 896961 D 516950 CDS YP_001835628.1 182683881 6217342 897864..898208 1 NC_010582.1 in Bacillus subtilis this protein is involved in the negative regulation of DNA replication initiation; interacts with DnaN and DnaA; DNA replication intiation control protein YabA 898208 6217342 SPCG_0911 Streptococcus pneumoniae CGSP14 DNA replication intiation control protein YabA YP_001835628.1 897864 D 516950 CDS YP_001835629.1 182683882 6218269 898211..899080 1 NC_010582.1 tetrapyrrole methylase family protein 899080 6218269 SPCG_0912 Streptococcus pneumoniae CGSP14 tetrapyrrole methylase family protein YP_001835629.1 898211 D 516950 CDS YP_001835630.1 182683883 6217105 899280..899825 1 NC_010582.1 hypothetical protein 899825 6217105 SPCG_0913 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835630.1 899280 D 516950 CDS YP_001835631.1 182683884 6217355 900078..900512 1 NC_010582.1 hypothetical protein 900512 6217355 SPCG_0914 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835631.1 900078 D 516950 CDS YP_001835632.1 182683885 6217634 complement(900570..900959) 1 NC_010582.1 IS1381 transposase protein B 900959 6217634 SPCG_0915 Streptococcus pneumoniae CGSP14 IS1381 transposase protein B YP_001835632.1 900570 R 516950 CDS YP_001835633.1 182683886 6217702 complement(900976..901377) 1 NC_010582.1 IS1381 transposase protein A 901377 6217702 SPCG_0916 Streptococcus pneumoniae CGSP14 IS1381 transposase protein A YP_001835633.1 900976 R 516950 CDS YP_001835634.1 182683887 6218045 901748..903154 1 NC_010582.1 TrmFO; Gid; glucose-inhibited division protein; similar to GidA; the gene from Bacillus subtilis encodes a tRNA-methyltransferase that utilizes folate as the carbon donor and bound flavin as reductant; modifies tRNA at position 54 (uridine) of the T-psi loop to form a C5-methyluridine; tRNA (uracil-5-)-methyltransferase Gid 903154 gidA 6218045 gidA Streptococcus pneumoniae CGSP14 tRNA (uracil-5-)-methyltransferase Gid YP_001835634.1 901748 D 516950 CDS YP_001835635.1 182683888 6218181 903232..903975 1 NC_010582.1 Catalyzes the phosphorylation of UMP to UDP; uridylate kinase 903975 pyrH 6218181 pyrH Streptococcus pneumoniae CGSP14 uridylate kinase YP_001835635.1 903232 D 516950 CDS YP_001835636.1 182683889 6216543 903984..904541 1 NC_010582.1 Rrf; Frr; ribosome-recycling factor; release factor 4; RF4; recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G; A GTPase-dependent process results in release of 50S from 70S; inhibited by release factor RF-1; essential for viability; structurally similar to tRNAs; ribosome recycling factor 904541 frr 6216543 frr Streptococcus pneumoniae CGSP14 ribosome recycling factor YP_001835636.1 903984 D 516950 CDS YP_001835637.1 182683890 6218158 904562..905455 1 NC_010582.1 hypothetical protein 905455 6218158 SPCG_0920 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835637.1 904562 D 516950 CDS YP_001835638.1 182683891 6216765 905464..905679 1 NC_010582.1 hypothetical protein 905679 6216765 SPCG_0921 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835638.1 905464 D 516950 CDS YP_001835639.1 182683892 6216768 905765..906733 1 NC_010582.1 phoH family protein 906733 phoL 6216768 phoL Streptococcus pneumoniae CGSP14 phoH family protein YP_001835639.1 905765 D 516950 CDS YP_001835640.1 182683893 6216598 906736..907203 1 NC_010582.1 hypothetical protein 907203 6216598 SPCG_0923 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835640.1 906736 D 516950 CDS YP_001835641.1 182683894 6217371 907215..907592 1 NC_010582.1 hypothetical protein 907592 6217371 SPCG_0924 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835641.1 907215 D 516950 CDS YP_001835642.1 182683895 6218449 907775..908275 1 NC_010582.1 acetyltransferase 908275 6218449 SPCG_0925 Streptococcus pneumoniae CGSP14 acetyltransferase YP_001835642.1 907775 D 516950 CDS YP_001835643.1 182683896 6217325 908278..908505 1 NC_010582.1 hypothetical protein 908505 6217325 SPCG_0926 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835643.1 908278 D 516950 CDS YP_001835644.1 182683897 6217237 complement(908909..909184) 1 NC_010582.1 alanine dehydrogenase 909184 6217237 SPCG_0927 Streptococcus pneumoniae CGSP14 alanine dehydrogenase YP_001835644.1 908909 R 516950 CDS YP_001835645.1 182683898 6216535 complement(909181..910008) 1 NC_010582.1 alanine dehydrogenase 910008 6216535 SPCG_0928 Streptococcus pneumoniae CGSP14 alanine dehydrogenase YP_001835645.1 909181 R 516950 CDS YP_001835646.1 182683899 6217158 910185..910754 1 NC_010582.1 acetyltransferase 910754 6217158 SPCG_0929 Streptococcus pneumoniae CGSP14 acetyltransferase YP_001835646.1 910185 D 516950 CDS YP_001835647.1 182683900 6217719 910822..911472 1 NC_010582.1 competence protein CelA 911472 celA 6217719 celA Streptococcus pneumoniae CGSP14 competence protein CelA YP_001835647.1 910822 D 516950 CDS YP_001835648.1 182683901 6218428 911456..913696 1 NC_010582.1 competence protein CelB 913696 celB 6218428 celB Streptococcus pneumoniae CGSP14 competence protein CelB YP_001835648.1 911456 D 516950 CDS YP_001835649.1 182683902 6217741 913875..914063 1 NC_010582.1 hypothetical protein 914063 6217741 SPCG_0932 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835649.1 913875 D 516950 CDS YP_001835650.1 182683903 6218384 914096..914623 1 NC_010582.1 ABC transporter ATP-binding protein 914623 6218384 SPCG_0933 Streptococcus pneumoniae CGSP14 ABC transporter ATP-binding protein YP_001835650.1 914096 D 516950 CDS YP_001835651.1 182683904 6218409 914679..915863 1 NC_010582.1 hypothetical protein 915863 6218409 SPCG_0934 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835651.1 914679 D 516950 CDS YP_001835652.1 182683905 6218320 916117..916704 1 NC_010582.1 IF-3 has several functions that are required and promote translation initiation including; preventing association of 70S by binding to 30S; monitoring codon-anticodon interactions by promoting disassociation of fMet-tRNA(fMet) from initiation complexes formed on leaderless mRNAs or incorrectly bound noninitiatior tRNAs and complexes with noncanonical start sites; stimulates codon-anticodon interactions at P-site; involved in moving mRNA to the P-site; and in recycling subunits; translation initiation factor IF-3 916704 infC 6218320 infC Streptococcus pneumoniae CGSP14 translation initiation factor IF-3 YP_001835652.1 916117 D 516950 CDS YP_001835653.1 182683906 6217039 916737..916937 1 NC_010582.1 50S ribosomal protein L35 916937 rpmI 6217039 rpmI Streptococcus pneumoniae CGSP14 50S ribosomal protein L35 YP_001835653.1 916737 D 516950 CDS YP_001835654.1 182683907 6218214 916989..917348 1 NC_010582.1 binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit; 50S ribosomal protein L20 917348 rplT 6218214 rplT Streptococcus pneumoniae CGSP14 50S ribosomal protein L20 YP_001835654.1 916989 D 516950 CDS YP_001835655.1 182683908 6216892 917355..917786 1 NC_010582.1 lactoylglutathione lyase 917786 lguL 6216892 lguL Streptococcus pneumoniae CGSP14 lactoylglutathione lyase YP_001835655.1 917355 D 516950 CDS YP_001835656.1 182683909 6217462 918036..918836 1 NC_010582.1 responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the pyrD subunit to the ultimate electron acceptor NAD(+); dihydroorotate dehydrogenase electron transfer subunit 918836 pyrDII 6217462 pyrDII Streptococcus pneumoniae CGSP14 dihydroorotate dehydrogenase electron transfer subunit YP_001835656.1 918036 D 516950 CDS YP_001835657.1 182683910 6216854 918793..919785 1 NC_010582.1 catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway, using a flavin nucleotide as an essential cofactor; subclass 1B is a heterotetramer consisting of two PyrDB subunits, similar to the PyrDA subunits and two PyrK subunits; dihydroorotate dehydrogenase 1B 919785 pyrD 6216854 pyrD Streptococcus pneumoniae CGSP14 dihydroorotate dehydrogenase 1B YP_001835657.1 918793 D 516950 CDS YP_001835658.1 182683911 6218274 919827..921860 1 NC_010582.1 endo-beta-N-acetylglucosaminidase 921860 lytB 6218274 lytB Streptococcus pneumoniae CGSP14 endo-beta-N-acetylglucosaminidase YP_001835658.1 919827 D 516950 CDS YP_001835659.1 182683912 6218453 complement(921921..923603) 1 NC_010582.1 adherence and virulence protein A 923603 flpA 6218453 flpA Streptococcus pneumoniae CGSP14 adherence and virulence protein A YP_001835659.1 921921 R 516950 CDS YP_001835660.1 182683913 6218348 923681..924178 1 NC_010582.1 metalloprotease 924178 6218348 SPCG_0943 Streptococcus pneumoniae CGSP14 metalloprotease YP_001835660.1 923681 D 516950 CDS YP_001835661.1 182683914 6218278 924159..924554 1 NC_010582.1 diacylglycerol kinase 924554 dgkA 6218278 dgkA Streptococcus pneumoniae CGSP14 diacylglycerol kinase YP_001835661.1 924159 D 516950 CDS YP_001835662.1 182683915 6218123 924571..925470 1 NC_010582.1 Era; Escherichia coli Ras-like protein; Bex; Bacillus Era-complementing segment; essential protein in Escherichia coli that is involved in many cellular processes; GTPase; binds the cell membrane through apparent C-terminal domain; mutants are arrested during the cell cycle; Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome; GTP-binding protein Era 925470 era 6218123 era Streptococcus pneumoniae CGSP14 GTP-binding protein Era YP_001835662.1 924571 D 516950 CDS YP_001835663.1 182683916 6218403 925519..926343 1 NC_010582.1 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases; formamidopyrimidine-DNA glycosylase 926343 mutM 6218403 mutM Streptococcus pneumoniae CGSP14 formamidopyrimidine-DNA glycosylase YP_001835663.1 925519 D 516950 CDS YP_001835664.1 182683917 6218473 926316..926948 1 NC_010582.1 catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; involved in coenzyme A biosynthesis; dephospho-CoA kinase 926948 coaE 6218473 coaE Streptococcus pneumoniae CGSP14 dephospho-CoA kinase YP_001835664.1 926316 D 516950 CDS YP_001835665.1 182683918 6218585 926935..928134 1 NC_010582.1 multi-drug resistance efflux pump 928134 pmrA 6218585 pmrA Streptococcus pneumoniae CGSP14 multi-drug resistance efflux pump YP_001835665.1 926935 D 516950 CDS YP_001835666.1 182683919 6218548 928323..928556 1 NC_010582.1 preprotein translocase subunit SecG 928556 secG 6218548 secG Streptococcus pneumoniae CGSP14 preprotein translocase subunit SecG YP_001835666.1 928323 D 516950 CDS YP_001835667.1 182683920 6218561 928658..931012 1 NC_010582.1 VacB/Rnb family exoribonuclease 931012 rnr 6218561 rnr Streptococcus pneumoniae CGSP14 VacB/Rnb family exoribonuclease YP_001835667.1 928658 D 516950 CDS YP_001835668.1 182683921 6218394 930975..931442 1 NC_010582.1 binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation; SsrA-binding protein 931442 smpB 6218394 smpB Streptococcus pneumoniae CGSP14 SsrA-binding protein YP_001835668.1 930975 D 516950 CDS YP_001835669.1 182683922 6218573 931452..932318 1 NC_010582.1 with TehA confers resistance to tellurite; tellurite resistance protein TehB 932318 tehB 6218573 tehB Streptococcus pneumoniae CGSP14 tellurite resistance protein TehB YP_001835669.1 931452 D 516950 CDS YP_001835670.1 182683923 6218259 932391..933344 1 NC_010582.1 competence protein CoiA 933344 coiA 6218259 coiA Streptococcus pneumoniae CGSP14 competence protein CoiA YP_001835670.1 932391 D 516950 CDS YP_001835671.1 182683924 6217348 933363..935165 1 NC_010582.1 oligoendopeptidase F 935165 6217348 SPCG_0954 Streptococcus pneumoniae CGSP14 oligoendopeptidase F YP_001835671.1 933363 D 516950 CDS YP_001835672.1 182683925 6217098 935167..935880 1 NC_010582.1 O-methyltransferase 935880 6217098 SPCG_0955 Streptococcus pneumoniae CGSP14 O-methyltransferase YP_001835672.1 935167 D 516950 CDS YP_001835673.1 182683926 6217092 935947..936888 1 NC_010582.1 cis/trans isomerase of peptidylprolyl; PPIase; membrane-bound lipoprotein; foldase protein PrsA 936888 prsA 6217092 prsA Streptococcus pneumoniae CGSP14 foldase protein PrsA YP_001835673.1 935947 D 516950 CDS YP_001835674.1 182683927 6218395 complement(937007..937348) 1 NC_010582.1 IS3-Spn1, transposase, truncation 937348 6218395 SPCG_0957 Streptococcus pneumoniae CGSP14 IS3-Spn1, transposase, truncation YP_001835674.1 937007 R 516950 CDS YP_001835675.1 182683928 6218485 complement(938109..938729) 1 NC_010582.1 phosphoglycerate mutase family protein 938729 gpmB 6218485 gpmB Streptococcus pneumoniae CGSP14 phosphoglycerate mutase family protein YP_001835675.1 938109 R 516950 CDS YP_001835676.1 182683929 6218138 complement(938729..939211) 1 NC_010582.1 regulatory protein 939211 ebsC 6218138 ebsC Streptococcus pneumoniae CGSP14 regulatory protein YP_001835676.1 938729 R 516950 CDS YP_001835677.1 182683930 6217787 complement(939211..940053) 1 NC_010582.1 hypothetical protein 940053 6217787 SPCG_0960 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835677.1 939211 R 516950 CDS YP_001835678.1 182683931 6217685 complement(940148..940948) 1 NC_010582.1 hypothetical protein 940948 6217685 SPCG_0961 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835678.1 940148 R 516950 CDS YP_001835679.1 182683932 6218216 941032..942471 1 NC_010582.1 forms a homotrimer; catalyzes the acetylation of glucosamine-1-phosphate and uridylation of N-acetylglucosamine-1-phosphate to produce UDP-GlcNAc; function in cell wall synthesis; bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase 942471 glmU 6218216 glmU Streptococcus pneumoniae CGSP14 bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase YP_001835679.1 941032 D 516950 CDS YP_001835680.1 182683933 6217640 942481..943026 1 NC_010582.1 mutT/nudix family protein 943026 6217640 SPCG_0963 Streptococcus pneumoniae CGSP14 mutT/nudix family protein YP_001835680.1 942481 D 516950 CDS YP_001835681.1 182683934 6216839 943005..943352 1 NC_010582.1 hypothetical protein 943352 6216839 SPCG_0964 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835681.1 943005 D 516950 CDS YP_001835682.1 182683935 6216755 943369..944061 1 NC_010582.1 enables the cleavage of the glycosidic bond in both 5'-methylthioadenosine and S-adenosylhomocysteine; 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase 944061 pfs 6216755 pfs Streptococcus pneumoniae CGSP14 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase YP_001835682.1 943369 D 516950 CDS YP_001835683.1 182683936 6216989 944138..944629 1 NC_010582.1 hypothetical protein 944629 6216989 SPCG_0966 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835683.1 944138 D 516950 CDS YP_001835684.1 182683937 6217239 944691..945317 1 NC_010582.1 3'-5' exonuclease of DNA polymerase III; DNA polymerase III subunit epsilon 945317 dnaQ 6217239 dnaQ Streptococcus pneumoniae CGSP14 DNA polymerase III subunit epsilon YP_001835684.1 944691 D 516950 CDS YP_001835685.1 182683938 6217015 945320..947089 1 NC_010582.1 hypothetical protein 947089 6217015 SPCG_0968 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835685.1 945320 D 516950 CDS YP_001835686.1 182683939 6216627 947285..947632 1 NC_010582.1 IS630-Spn1 transposase 947632 6216627 SPCG_0969 Streptococcus pneumoniae CGSP14 IS630-Spn1 transposase YP_001835686.1 947285 D 516950 CDS YP_001835687.1 182683940 6218280 947811..947951 1 NC_010582.1 hypothetical protein 947951 6218280 SPCG_0970 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835687.1 947811 D 516950 CDS YP_001835688.1 182683941 6218279 948112..948312 1 NC_010582.1 hypothetical protein 948312 6218279 SPCG_0971 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835688.1 948112 D 516950 CDS YP_001835689.1 182683942 6218268 complement(948131..948763) 1 NC_010582.1 hypothetical protein 948763 6218268 SPCG_0972 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835689.1 948131 R 516950 CDS YP_001835690.1 182683943 6217305 948989..949696 1 NC_010582.1 cytochrome c-type biogenesis protein CcdA 949696 ccdA 6217305 ccdA Streptococcus pneumoniae CGSP14 cytochrome c-type biogenesis protein CcdA YP_001835690.1 948989 D 516950 CDS YP_001835691.1 182683944 6218558 949689..950264 1 NC_010582.1 thioredoxin 950264 6218558 SPCG_0974 Streptococcus pneumoniae CGSP14 thioredoxin YP_001835691.1 949689 D 516950 CDS YP_001835692.1 182683945 6216653 950626..952029 1 NC_010582.1 amino acid permease family protein 952029 yfnA 6216653 yfnA Streptococcus pneumoniae CGSP14 amino acid permease family protein YP_001835692.1 950626 D 516950 CDS YP_001835693.1 182683946 6216674 952154..953089 1 NC_010582.1 adhesion lipoprotein 953089 lmb 6216674 lmb Streptococcus pneumoniae CGSP14 adhesion lipoprotein YP_001835693.1 952154 D 516950 CDS YP_001835694.1 182683947 6218515 953097..955601 1 NC_010582.1 hypothetical protein 955601 6218515 SPCG_0977 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835694.1 953097 D 516950 CDS YP_001835695.1 182683948 6216834 955811..958930 1 NC_010582.1 hypothetical protein 958930 6216834 SPCG_0978 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835695.1 955811 D 516950 CDS YP_001835696.1 182683949 6217247 959760..959900 1 NC_010582.1 hypothetical protein 959900 6217247 SPCG_0979 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835696.1 959760 D 516950 CDS YP_001835697.1 182683950 6217008 959934..960416 1 NC_010582.1 histidine triad protein E , truncation 960416 6217008 SPCG_0980 Streptococcus pneumoniae CGSP14 histidine triad protein E , truncation YP_001835697.1 959934 D 516950 CDS YP_001835698.1 182683952 6216874 complement(960525..960746) 1 NC_010582.1 hypothetical protein 960746 6216874 SPCG_0981 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835698.1 960525 R 516950 CDS YP_001835699.1 182683951 6216960 960732..960968 1 NC_010582.1 hypothetical protein 960968 6216960 SPCG_0982 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835699.1 960732 D 516950 CDS YP_001835700.1 182683953 6216666 960997..961329 1 NC_010582.1 hypothetical protein 961329 6216666 SPCG_0983 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835700.1 960997 D 516950 CDS YP_001835701.1 182683954 6217920 complement(961365..962588) 1 NC_010582.1 catalyzes the release of the N-terminal amino acid from a tripeptide; peptidase T 962588 pepT 6217920 pepT Streptococcus pneumoniae CGSP14 peptidase T YP_001835701.1 961365 R 516950 CDS YP_001835702.1 182683955 6218249 962743..963837 1 NC_010582.1 ferrochelatase 963837 hemH 6218249 hemH Streptococcus pneumoniae CGSP14 ferrochelatase YP_001835702.1 962743 D 516950 CDS YP_001835703.1 182683956 6216418 complement(963884..963976) 1 NC_010582.1 hypothetical protein 963976 6216418 SPCG_0986 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835703.1 963884 R 516950 CDS YP_001835704.1 182683957 6216440 complement(963992..964744) 1 NC_010582.1 degenerate transposase 964744 6216440 SPCG_0987 Streptococcus pneumoniae CGSP14 degenerate transposase YP_001835704.1 963992 R 516950 CDS YP_001835705.1 182683958 6218483 complement(964737..965282) 1 NC_010582.1 degenerate transposase 965282 6218483 SPCG_0988 Streptococcus pneumoniae CGSP14 degenerate transposase YP_001835705.1 964737 R 516950 CDS YP_001835706.1 182683959 6216326 complement(965398..965775) 1 NC_010582.1 large conductance mechanosensitive channel protein MscL 965775 mscL 6216326 mscL Streptococcus pneumoniae CGSP14 large conductance mechanosensitive channel protein MscL YP_001835706.1 965398 R 516950 CDS YP_001835707.1 182683960 6217453 complement(965857..966288) 1 NC_010582.1 gtrA family protein 966288 6217453 SPCG_0990 Streptococcus pneumoniae CGSP14 gtrA family protein YP_001835707.1 965857 R 516950 CDS YP_001835708.1 182683961 6217929 966339..966920 1 NC_010582.1 hypothetical protein 966920 6217929 SPCG_0991 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835708.1 966339 D 516950 CDS YP_001835709.1 182683962 6218095 967198..967452 1 NC_010582.1 hypothetical protein 967452 6218095 SPCG_0992 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835709.1 967198 D 516950 CDS YP_001835710.1 182683963 6218079 967678..968754 1 NC_010582.1 catalyzes the formation of 4-aspartyl phosphate from aspartate 4-semialdehyde; aspartate-semialdehyde dehydrogenase 968754 asd 6218079 asd Streptococcus pneumoniae CGSP14 aspartate-semialdehyde dehydrogenase YP_001835710.1 967678 D 516950 CDS YP_001835711.1 182683964 6218321 968810..969745 1 NC_010582.1 catalyzes the formation of dihydrodipicolinate from L-aspartate 4-semialdehyde and pyruvate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate synthase 969745 dapA 6218321 dapA Streptococcus pneumoniae CGSP14 dihydrodipicolinate synthase YP_001835711.1 968810 D 516950 CDS YP_001835712.1 182683965 6218380 complement(969792..971231) 1 NC_010582.1 in Escherichia coli this protein is involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2-thiouridine, which is found in the wobble position of some tRNAs and affects ribosomal frameshifting; shows potassium-dependent dimerization and GTP hydrolysis; also involved in regulation of glutamate-dependent acid resistance and activation of gadE; tRNA modification GTPase TrmE 971231 trmE 6218380 trmE Streptococcus pneumoniae CGSP14 tRNA modification GTPase TrmE YP_001835712.1 969792 R 516950 CDS YP_001835713.1 182683966 6218540 complement(971302..971526) 1 NC_010582.1 4-OT; member of subfamily 5; forms a dimer; the function in the Escherichia coli cell is unknown; 4-oxalocrotonate tautomerase 971526 xylH 6218540 xylH Streptococcus pneumoniae CGSP14 4-oxalocrotonate tautomerase YP_001835713.1 971302 R 516950 CDS YP_001835714.1 182683967 6217129 971607..972197 1 NC_010582.1 catalyzes the formation of thymidine 5'-phosphate from thymidine; thymidine kinase 972197 tdk 6217129 tdk Streptococcus pneumoniae CGSP14 thymidine kinase YP_001835714.1 971607 D 516950 CDS YP_001835715.1 182683968 6217245 972194..973273 1 NC_010582.1 recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2; peptide chain release factor 1 973273 prfA 6217245 prfA Streptococcus pneumoniae CGSP14 peptide chain release factor 1 YP_001835715.1 972194 D 516950 CDS YP_001835716.1 182683969 6218311 973273..974112 1 NC_010582.1 hemK protein 974112 hemK 6218311 hemK Streptococcus pneumoniae CGSP14 hemK protein YP_001835716.1 973273 D 516950 CDS YP_001835717.1 182683970 6218390 974069..974698 1 NC_010582.1 Sua5/YciO/YrdC family protein 974698 6218390 SPCG_1000 Streptococcus pneumoniae CGSP14 Sua5/YciO/YrdC family protein YP_001835717.1 974069 D 516950 CDS YP_001835718.1 182683971 6217779 974661..975131 1 NC_010582.1 acetyltransferase 975131 6217779 SPCG_1001 Streptococcus pneumoniae CGSP14 acetyltransferase YP_001835718.1 974661 D 516950 CDS YP_001835719.1 182683972 6217457 975193..976449 1 NC_010582.1 catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate; serine hydroxymethyltransferase 976449 glyA 6217457 glyA Streptococcus pneumoniae CGSP14 serine hydroxymethyltransferase YP_001835719.1 975193 D 516950 CDS YP_001835720.1 182683973 6217200 976424..977431 1 NC_010582.1 hypothetical protein 977431 6217200 SPCG_1003 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835720.1 976424 D 516950 CDS YP_001835721.1 182683974 6217028 977431..978045 1 NC_010582.1 hypothetical protein 978045 6217028 SPCG_1004 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835721.1 977431 D 516950 CDS YP_001835722.1 182683975 6216987 978119..979093 1 NC_010582.1 hypothetical protein 979093 6216987 SPCG_1005 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835722.1 978119 D 516950 CDS YP_001835723.1 182683976 6216819 979062..979154 1 NC_010582.1 hypothetical protein 979154 6216819 SPCG_1006 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835723.1 979062 D 516950 CDS YP_001835724.1 182683977 6216782 979167..980792 1 NC_010582.1 RNA methyltransferase 980792 6216782 SPCG_1007 Streptococcus pneumoniae CGSP14 RNA methyltransferase YP_001835724.1 979167 D 516950 CDS YP_001835725.1 182683978 6216553 981918..982019 1 NC_010582.1 hypothetical protein 982019 6216553 SPCG_1008 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835725.1 981918 D 516950 CDS YP_001835726.1 182683979 6216605 982140..983165 1 NC_010582.1 iron-compound ABC transporter iron compound-binding protein 983165 6216605 SPCG_1009 Streptococcus pneumoniae CGSP14 iron-compound ABC transporter iron compound-binding protein YP_001835726.1 982140 D 516950 CDS YP_001835727.1 182683981 6216875 complement(983136..983690) 1 NC_010582.1 hypothetical protein 983690 6216875 SPCG_1010 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835727.1 983136 R 516950 CDS YP_001835728.1 182683980 6218523 983143..984162 1 NC_010582.1 iron-compound ABC transporter permease 984162 6218523 SPCG_1011 Streptococcus pneumoniae CGSP14 iron-compound ABC transporter permease YP_001835728.1 983143 D 516950 CDS YP_001835729.1 182683982 6218200 984162..985169 1 NC_010582.1 iron-compound ABC transporter permease 985169 6218200 SPCG_1012 Streptococcus pneumoniae CGSP14 iron-compound ABC transporter permease YP_001835729.1 984162 D 516950 CDS YP_001835730.1 182683983 6218046 985169..985963 1 NC_010582.1 iron-compound ABC transporter ATP-binding protein 985963 6218046 SPCG_1013 Streptococcus pneumoniae CGSP14 iron-compound ABC transporter ATP-binding protein YP_001835730.1 985169 D 516950 CDS YP_001835731.1 182683984 6216659 986832..987149 1 NC_010582.1 hypothetical protein 987149 6216659 SPCG_1014 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835731.1 986832 D 516950 CDS YP_001835732.1 182683985 6217763 987454..988167 1 NC_010582.1 hypothetical protein 988167 6217763 SPCG_1015 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835732.1 987454 D 516950 CDS YP_001835733.1 182683986 6218318 988185..989102 1 NC_010582.1 hypothetical protein 989102 6218318 SPCG_1016 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835733.1 988185 D 516950 CDS YP_001835734.1 182683987 6218267 989535..989939 1 NC_010582.1 hypothetical protein 989939 6218267 SPCG_1017 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835734.1 989535 D 516950 CDS YP_001835735.1 182683988 6218206 990113..990841 1 NC_010582.1 phage-associated protein 990841 6218206 SPCG_1018 Streptococcus pneumoniae CGSP14 phage-associated protein YP_001835735.1 990113 D 516950 CDS YP_001835736.1 182683989 6217992 991525..991686 1 NC_010582.1 hypothetical protein 991686 6217992 SPCG_1019 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835736.1 991525 D 516950 CDS YP_001835737.1 182683990 6217811 991778..993457 1 NC_010582.1 resolvase family site-specific recombinase 993457 6217811 SPCG_1020 Streptococcus pneumoniae CGSP14 resolvase family site-specific recombinase YP_001835737.1 991778 D 516950 CDS YP_001835738.1 182683991 6218164 993680..994291 1 NC_010582.1 hypothetical protein 994291 6218164 SPCG_1021 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835738.1 993680 D 516950 CDS YP_001835739.1 182683992 6218113 994604..994801 1 NC_010582.1 hypothetical protein 994801 6218113 SPCG_1022 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835739.1 994604 D 516950 CDS YP_001835740.1 182683993 6217822 994863..995621 1 NC_010582.1 hypothetical protein 995621 6217822 SPCG_1023 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835740.1 994863 D 516950 CDS YP_001835741.1 182683994 6217844 995679..996533 1 NC_010582.1 hydrolase 996533 6217844 SPCG_1024 Streptococcus pneumoniae CGSP14 hydrolase YP_001835741.1 995679 D 516950 CDS YP_001835742.1 182683995 6216692 996594..997529 1 NC_010582.1 hypothetical protein 997529 6216692 SPCG_1025 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835742.1 996594 D 516950 CDS YP_001835743.1 182683996 6218118 997668..999431 1 NC_010582.1 neopullulanase 999431 nplT 6218118 nplT Streptococcus pneumoniae CGSP14 neopullulanase YP_001835743.1 997668 D 516950 CDS YP_001835744.1 182683997 6216956 999517..999834 1 NC_010582.1 hypothetical protein 999834 6216956 SPCG_1027 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835744.1 999517 D 516950 CDS YP_001835745.1 182683998 6216958 999880..1000161 1 NC_010582.1 hypothetical protein 1000161 6216958 SPCG_1028 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835745.1 999880 D 516950 CDS YP_001835746.1 182683999 6217113 1000549..1001082 1 NC_010582.1 transcriptional regulator 1001082 6217113 SPCG_1029 Streptococcus pneumoniae CGSP14 transcriptional regulator YP_001835746.1 1000549 D 516950 CDS YP_001835747.1 182684000 6217500 1001082..1001843 1 NC_010582.1 hypothetical protein 1001843 6217500 SPCG_1030 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835747.1 1001082 D 516950 CDS YP_001835748.1 182684001 6217845 1001871..1002647 1 NC_010582.1 phosphoesterase 1002647 6217845 SPCG_1031 Streptococcus pneumoniae CGSP14 phosphoesterase YP_001835748.1 1001871 D 516950 CDS YP_001835749.1 182684002 6217837 1002650..1003027 1 NC_010582.1 hypothetical protein 1003027 6217837 SPCG_1032 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835749.1 1002650 D 516950 CDS YP_001835750.1 182684003 6218168 1003859..1004218 1 NC_010582.1 Tn5252, ORF 10 protein 1004218 6218168 SPCG_1033 Streptococcus pneumoniae CGSP14 Tn5252, ORF 10 protein YP_001835750.1 1003859 D 516950 CDS YP_001835751.1 182684004 6217392 1004228..1004593 1 NC_010582.1 Tn5252, ORF 9 protein 1004593 6217392 SPCG_1034 Streptococcus pneumoniae CGSP14 Tn5252, ORF 9 protein YP_001835751.1 1004228 D 516950 CDS YP_001835752.1 182684005 6217434 1004580..1006430 1 NC_010582.1 Tn5252, relaxase 1006430 6217434 SPCG_1035 Streptococcus pneumoniae CGSP14 Tn5252, relaxase YP_001835752.1 1004580 D 516950 CDS YP_001835753.1 182684006 6217716 1006683..1007363 1 NC_010582.1 degenerate transposase 1007363 6217716 SPCG_1036 Streptococcus pneumoniae CGSP14 degenerate transposase YP_001835753.1 1006683 D 516950 CDS YP_001835754.1 182684007 6217736 1007381..1007650 1 NC_010582.1 degenerate transposase 1007650 6217736 SPCG_1037 Streptococcus pneumoniae CGSP14 degenerate transposase YP_001835754.1 1007381 D 516950 CDS YP_001835755.1 182684008 6218546 complement(1008811..1009809) 1 NC_010582.1 IS1239 transposase 1009809 6218546 SPCG_1038 Streptococcus pneumoniae CGSP14 IS1239 transposase YP_001835755.1 1008811 R 516950 CDS YP_001835756.1 182684009 6217452 1010368..1011411 1 NC_010582.1 hypothetical protein 1011411 6217452 SPCG_1039 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835756.1 1010368 D 516950 CDS YP_001835757.1 182684010 6217713 1011560..1013665 1 NC_010582.1 catalyzes the ATP-dependent breakage of single-stranded DNA followed by passage and rejoining, maintains net negative superhelicity; DNA topoisomerase I 1013665 topA 6217713 topA Streptococcus pneumoniae CGSP14 DNA topoisomerase I YP_001835757.1 1011560 D 516950 CDS YP_001835758.1 182684011 6216575 1013886..1014245 1 NC_010582.1 hypothetical protein 1014245 6216575 SPCG_1041 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835758.1 1013886 D 516950 CDS YP_001835759.1 182684012 6217242 1014338..1014970 1 NC_010582.1 copper homeostasis protein CutC 1014970 cutC 6217242 cutC Streptococcus pneumoniae CGSP14 copper homeostasis protein CutC YP_001835759.1 1014338 D 516950 CDS YP_001835760.1 182684013 6217156 1015014..1015670 1 NC_010582.1 hypothetical protein 1015670 6217156 SPCG_1043 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835760.1 1015014 D 516950 CDS YP_001835761.1 182684014 6217573 1015689..1016222 1 NC_010582.1 hypothetical protein 1016222 6217573 SPCG_1044 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835761.1 1015689 D 516950 CDS YP_001835762.1 182684015 6216629 1016338..1016772 1 NC_010582.1 hypothetical protein 1016772 6216629 SPCG_1045 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835762.1 1016338 D 516950 CDS YP_001835763.1 182684016 6216740 1016784..1017821 1 NC_010582.1 catalyzes the oxidation of 3-isopropylmalate to 3-carboxy-4-methyl-2-oxopentanoate in leucine biosynthesis; 3-isopropylmalate dehydrogenase 1017821 6216740 SPCG_1046 Streptococcus pneumoniae CGSP14 3-isopropylmalate dehydrogenase YP_001835763.1 1016784 D 516950 CDS YP_001835764.1 182684017 6217468 1017818..1018087 1 NC_010582.1 hypothetical protein 1018087 6217468 SPCG_1047 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835764.1 1017818 D 516950 CDS YP_001835765.1 182684018 6218549 1018091..1018450 1 NC_010582.1 hypothetical protein 1018450 6218549 SPCG_1048 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835765.1 1018091 D 516950 CDS YP_001835766.1 182684019 6217671 1018669..1018812 1 NC_010582.1 hypothetical protein 1018812 6217671 SPCG_1049 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835766.1 1018669 D 516950 CDS YP_001835767.1 182684020 6218572 1018912..1019085 1 NC_010582.1 hypothetical protein 1019085 6218572 SPCG_1050 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835767.1 1018912 D 516950 CDS YP_001835768.1 182684021 6217038 1019066..1019236 1 NC_010582.1 hypothetical protein 1019236 6217038 SPCG_1051 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835768.1 1019066 D 516950 CDS YP_001835769.1 182684022 6218016 1019398..1021332 1 NC_010582.1 endonuclease 1021332 6218016 SPCG_1052 Streptococcus pneumoniae CGSP14 endonuclease YP_001835769.1 1019398 D 516950 CDS YP_001835770.1 182684023 6217833 1021292..1022635 1 NC_010582.1 hypothetical protein 1022635 6217833 SPCG_1053 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835770.1 1021292 D 516950 CDS YP_001835771.1 182684024 6216688 1022810..1023796 1 NC_010582.1 guanosine 5'-monophosphate oxidoreductase 1023796 guaC 6216688 guaC Streptococcus pneumoniae CGSP14 guanosine 5'-monophosphate oxidoreductase YP_001835771.1 1022810 D 516950 CDS YP_001835772.1 182684025 6217532 1024114..1024812 1 NC_010582.1 cytoplasmic enzyme involved in processing rRNA and some mRNAs; substrates typically have dsRNA regions; forms a homodimer; have N-terminal nuclease and C-terminal RNA-binding domains; requires magnesium as preferred ion for activity; ribonuclease III 1024812 rnc 6217532 rnc Streptococcus pneumoniae CGSP14 ribonuclease III YP_001835772.1 1024114 D 516950 CDS YP_001835773.1 182684026 6217737 1024803..1028342 1 NC_010582.1 hypothetical protein 1028342 6217737 SPCG_1056 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835773.1 1024803 D 516950 CDS YP_001835774.1 182684027 6217786 1028339..1029133 1 NC_010582.1 cof family protein 1029133 6217786 SPCG_1057 Streptococcus pneumoniae CGSP14 cof family protein YP_001835774.1 1028339 D 516950 CDS YP_001835775.1 182684028 6218157 1029133..1029951 1 NC_010582.1 cof family protein 1029951 6218157 SPCG_1058 Streptococcus pneumoniae CGSP14 cof family protein YP_001835775.1 1029133 D 516950 CDS YP_001835776.1 182684029 6217826 1029955..1031244 1 NC_010582.1 signal recognition particle-docking protein FtsY 1031244 ftsY 6217826 ftsY Streptococcus pneumoniae CGSP14 signal recognition particle-docking protein FtsY YP_001835776.1 1029955 D 516950 CDS YP_001835777.1 182684030 6217853 complement(1031290..1032777) 1 NC_010582.1 catalyzes the formation of D-glucono-1,5-lactone 6-phosphate from D-glucose 6-phosphate; glucose-6-phosphate 1-dehydrogenase 1032777 zwf 6217853 zwf Streptococcus pneumoniae CGSP14 glucose-6-phosphate 1-dehydrogenase YP_001835777.1 1031290 R 516950 CDS YP_001835778.1 182684031 6217662 complement(1032926..1033666) 1 NC_010582.1 amino acid ABC transporter ATP-binding protein 1033666 6217662 SPCG_1061 Streptococcus pneumoniae CGSP14 amino acid ABC transporter ATP-binding protein YP_001835778.1 1032926 R 516950 CDS YP_001835779.1 182684032 6218042 complement(1033666..1035831) 1 NC_010582.1 amino acid ABC transporter amino acid-binding protein/permease 1035831 6218042 SPCG_1062 Streptococcus pneumoniae CGSP14 amino acid ABC transporter amino acid-binding protein/permease YP_001835779.1 1033666 R 516950 CDS YP_001835780.1 182684033 6217278 1036000..1036953 1 NC_010582.1 hypothetical protein 1036953 6217278 SPCG_1063 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835780.1 1036000 D 516950 CDS YP_001835781.1 182684034 6217721 1037030..1039018 1 NC_010582.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion; excinuclease ABC subunit B 1039018 uvrB 6217721 uvrB Streptococcus pneumoniae CGSP14 excinuclease ABC subunit B YP_001835781.1 1037030 D 516950 CDS YP_001835782.1 182684035 6216371 1039028..1039591 1 NC_010582.1 acetyltransferase 1039591 6216371 SPCG_1065 Streptococcus pneumoniae CGSP14 acetyltransferase YP_001835782.1 1039028 D 516950 CDS YP_001835783.1 182684036 6217384 1039557..1040045 1 NC_010582.1 acetyltransferase 1040045 6217384 SPCG_1066 Streptococcus pneumoniae CGSP14 acetyltransferase YP_001835783.1 1039557 D 516950 CDS YP_001835784.1 182684037 6217528 1040119..1040586 1 NC_010582.1 mutT/nudix family protein 1040586 6217528 SPCG_1067 Streptococcus pneumoniae CGSP14 mutT/nudix family protein YP_001835784.1 1040119 D 516950 CDS YP_001835785.1 182684038 6217376 complement(1040583..1041098) 1 NC_010582.1 biotin repressor family transcriptional regulator 1041098 6217376 SPCG_1068 Streptococcus pneumoniae CGSP14 biotin repressor family transcriptional regulator YP_001835785.1 1040583 R 516950 CDS YP_001835786.1 182684039 6218053 complement(1041110..1041691) 1 NC_010582.1 hypothetical protein 1041691 6218053 SPCG_1069 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835786.1 1041110 R 516950 CDS YP_001835787.1 182684040 6217910 complement(1041919..1042482) 1 NC_010582.1 membrane protein 1042482 6217910 SPCG_1070 Streptococcus pneumoniae CGSP14 membrane protein YP_001835787.1 1041919 R 516950 CDS YP_001835788.1 182684041 6217915 complement(1042466..1043017) 1 NC_010582.1 decarboxylates 4-phosphopantothenoylcysteine to form 4'-phosphopantotheine.; phosphopantothenoylcysteine decarboxylase 1043017 6217915 SPCG_1071 Streptococcus pneumoniae CGSP14 phosphopantothenoylcysteine decarboxylase YP_001835788.1 1042466 R 516950 CDS YP_001835789.1 182684042 6217753 complement(1043029..1043733) 1 NC_010582.1 phosphopantothenate--cysteine ligase 1043733 6217753 SPCG_1072 Streptococcus pneumoniae CGSP14 phosphopantothenate--cysteine ligase YP_001835789.1 1043029 R 516950 CDS YP_001835790.1 182684043 6217567 1043948..1045618 1 NC_010582.1 catalyzes the formation of 10-formyltetrahydrofolate from formate and tetrahydrofolate; formate--tetrahydrofolate ligase 1045618 fhs 6217567 fhs Streptococcus pneumoniae CGSP14 formate--tetrahydrofolate ligase YP_001835790.1 1043948 D 516950 CDS YP_001835791.1 182684044 6217659 1045947..1047122 1 NC_010582.1 A/G-specific adenine glycosylase 1047122 mutY 6217659 mutY Streptococcus pneumoniae CGSP14 A/G-specific adenine glycosylase YP_001835791.1 1045947 D 516950 CDS YP_001835792.1 182684045 6216506 1047126..1047881 1 NC_010582.1 DNA-binding response regulator 1047881 6216506 SPCG_1075 Streptococcus pneumoniae CGSP14 DNA-binding response regulator YP_001835792.1 1047126 D 516950 CDS YP_001835793.1 182684046 6217121 1047874..1049223 1 NC_010582.1 sensory box sensor histidine kinase 1049223 6217121 SPCG_1076 Streptococcus pneumoniae CGSP14 sensory box sensor histidine kinase YP_001835793.1 1047874 D 516950 CDS YP_001835794.1 182684047 6217487 1049225..1050034 1 NC_010582.1 vicX protein 1050034 vicX 6217487 vicX Streptococcus pneumoniae CGSP14 vicX protein YP_001835794.1 1049225 D 516950 CDS YP_001835795.1 182684048 6217391 1050065..1050367 1 NC_010582.1 hypothetical protein 1050367 6217391 SPCG_1078 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835795.1 1050065 D 516950 CDS YP_001835796.1 182684049 6217968 1050360..1050623 1 NC_010582.1 hypothetical protein 1050623 6217968 SPCG_1079 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835796.1 1050360 D 516950 CDS YP_001835797.1 182684050 6217252 1050598..1051254 1 NC_010582.1 ion transporter 1051254 6217252 SPCG_1080 Streptococcus pneumoniae CGSP14 ion transporter YP_001835797.1 1050598 D 516950 CDS YP_001835798.1 182684051 6217533 complement(1051582..1052580) 1 NC_010582.1 Converts (S)-lactate and NAD(+) to pyruvate and NADH; L-lactate dehydrogenase 1052580 ldh 6217533 ldh Streptococcus pneumoniae CGSP14 L-lactate dehydrogenase YP_001835798.1 1051582 R 516950 CDS YP_001835799.1 182684052 6217838 1052705..1055230 1 NC_010582.1 negatively supercoils closed circular double-stranded DNA; DNA gyrase subunit A 1055230 6217838 SPCG_1082 Streptococcus pneumoniae CGSP14 DNA gyrase subunit A YP_001835799.1 1052705 D 516950 CDS YP_001835800.1 182684053 6218170 1055230..1055973 1 NC_010582.1 hypothetical protein 1055973 6218170 SPCG_1083 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835800.1 1055230 D 516950 CDS YP_001835801.1 182684054 6217282 1056217..1057014 1 NC_010582.1 FNT family protein 1057014 6217282 SPCG_1084 Streptococcus pneumoniae CGSP14 FNT family protein YP_001835801.1 1056217 D 516950 CDS YP_001835802.1 182684055 6218077 1057162..1057284 1 NC_010582.1 O-acetylhomoserine sulfhydrylase, truncation 1057284 6218077 SPCG_1085 Streptococcus pneumoniae CGSP14 O-acetylhomoserine sulfhydrylase, truncation YP_001835802.1 1057162 D 516950 CDS YP_001835803.1 182684056 6217364 1057306..1058421 1 NC_010582.1 O-acetylhomoserine sulfhydrylase, truncation 1058421 6217364 SPCG_1086 Streptococcus pneumoniae CGSP14 O-acetylhomoserine sulfhydrylase, truncation YP_001835803.1 1057306 D 516950 CDS YP_001835804.1 182684057 6218413 1058517..1059791 1 NC_010582.1 hypothetical protein 1059791 6218413 SPCG_1087 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835804.1 1058517 D 516950 CDS YP_001835805.1 182684058 6217544 1059803..1062988 1 NC_010582.1 hypothetical protein 1062988 6217544 SPCG_1088 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835805.1 1059803 D 516950 CDS YP_001835806.1 182684059 6216372 1063089..1063967 1 NC_010582.1 catalyzes isomerization of specific uridines in RNA to pseudouridine; responsible for residues in T loops of many tRNAs; tRNA pseudouridine synthase B 1063967 truB 6216372 truB Streptococcus pneumoniae CGSP14 tRNA pseudouridine synthase B YP_001835806.1 1063089 D 516950 CDS YP_001835807.1 182684060 6217744 1064116..1064211 1 NC_010582.1 hypothetical protein 1064211 6217744 SPCG_1090 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835807.1 1064116 D 516950 CDS YP_001835808.1 182684061 6216409 1064208..1064510 1 NC_010582.1 hypothetical protein 1064510 6216409 SPCG_1091 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835808.1 1064208 D 516950 CDS YP_001835809.1 182684062 6217658 1064618..1065256 1 NC_010582.1 functions in pyrimidine salvage; pyrimidine ribonucleoside kinase; phosphorylates nucleosides or dinucleosides to make UMP or CMP using ATP or GTP as the donor; uridine kinase 1065256 udK 6217658 udK Streptococcus pneumoniae CGSP14 uridine kinase YP_001835809.1 1064618 D 516950 CDS YP_001835810.1 182684063 6217890 1065378..1066724 1 NC_010582.1 bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides; exodeoxyribonuclease VII large subunit 1066724 xseA 6217890 xseA Streptococcus pneumoniae CGSP14 exodeoxyribonuclease VII large subunit YP_001835810.1 1065378 D 516950 CDS YP_001835811.1 182684064 6217531 1066702..1066914 1 NC_010582.1 catalyzes the bidirectional exonucleolytic cleavage of DNA; exodeoxyribonuclease VII small subunit 1066914 xseB 6217531 xseB Streptococcus pneumoniae CGSP14 exodeoxyribonuclease VII small subunit YP_001835811.1 1066702 D 516950 CDS YP_001835812.1 182684065 6217440 1066911..1067786 1 NC_010582.1 geranyltranstransferase 1067786 6217440 SPCG_1095 Streptococcus pneumoniae CGSP14 geranyltranstransferase YP_001835812.1 1066911 D 516950 CDS YP_001835813.1 182684066 6217439 1067779..1068594 1 NC_010582.1 hemolysin A 1068594 6217439 SPCG_1096 Streptococcus pneumoniae CGSP14 hemolysin A YP_001835813.1 1067779 D 516950 CDS YP_001835814.1 182684067 6217732 1068587..1069018 1 NC_010582.1 transcriptional repressor 1069018 ahrC 6217732 ahrC Streptococcus pneumoniae CGSP14 transcriptional repressor YP_001835814.1 1068587 D 516950 CDS YP_001835815.1 182684068 6218007 1069025..1070692 1 NC_010582.1 DNA repair protein RecN 1070692 recN 6218007 recN Streptococcus pneumoniae CGSP14 DNA repair protein RecN YP_001835815.1 1069025 D 516950 CDS YP_001835816.1 182684069 6217543 1070694..1071422 1 NC_010582.1 serine/threonine protein phosphatase 1071422 pphA 6217543 pphA Streptococcus pneumoniae CGSP14 serine/threonine protein phosphatase YP_001835816.1 1070694 D 516950 CDS YP_001835817.1 182684070 6218443 1071438..1073324 1 NC_010582.1 binds to the ribosome on the universally-conserved alpha-sarcin loop; GTP-binding protein LepA 1073324 6218443 SPCG_1100 Streptococcus pneumoniae CGSP14 GTP-binding protein LepA YP_001835817.1 1071438 D 516950 CDS YP_001835818.1 182684071 6218586 1073737..1074258 1 NC_010582.1 PTS system transporter subunit IIA 1074258 6218586 SPCG_1101 Streptococcus pneumoniae CGSP14 PTS system transporter subunit IIA YP_001835818.1 1073737 D 516950 CDS YP_001835819.1 182684072 6218275 1074296..1074598 1 NC_010582.1 hypothetical protein 1074598 6218275 SPCG_1102 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835819.1 1074296 D 516950 CDS YP_001835820.1 182684073 6217937 1075036..1075425 1 NC_010582.1 IS1381 transposase protein B 1075425 6217937 SPCG_1103 Streptococcus pneumoniae CGSP14 IS1381 transposase protein B YP_001835820.1 1075036 D 516950 CDS YP_001835821.1 182684074 6217127 1075594..1075938 1 NC_010582.1 galactose mutarotase 1075938 6217127 SPCG_1104 Streptococcus pneumoniae CGSP14 galactose mutarotase YP_001835821.1 1075594 D 516950 CDS YP_001835822.1 182684075 6217984 1076095..1076520 1 NC_010582.1 catalyzes the interconversion of galactose 6-phosphate to tagatose 6-phosphate; tagatose pathway for galactose utilization; galactose-6-phosphate isomerase subunit LacA 1076520 lacA 6217984 lacA Streptococcus pneumoniae CGSP14 galactose-6-phosphate isomerase subunit LacA YP_001835822.1 1076095 D 516950 CDS YP_001835823.1 182684076 6217990 1076551..1077066 1 NC_010582.1 catalyzes the interconversion of galactose 6-phosphate to tagatose 6-phosphate; galactose-6-phosphate isomerase subunit LacB 1077066 lacB 6217990 lacB Streptococcus pneumoniae CGSP14 galactose-6-phosphate isomerase subunit LacB YP_001835823.1 1076551 D 516950 CDS YP_001835824.1 182684077 6217879 1077077..1078006 1 NC_010582.1 catalyzes the formation of tagatose 1,6-bisphosphate from tagatose 6-phosphate and ATP; tagatose-6-phosphate kinase 1078006 lacC 6217879 lacC Streptococcus pneumoniae CGSP14 tagatose-6-phosphate kinase YP_001835824.1 1077077 D 516950 CDS YP_001835825.1 182684078 6217572 1078008..1078988 1 NC_010582.1 catalyzes the reversible reaction of dihydroxyacetone phosphate with glyceraldehyde 3-phosphate to produce tagatose 1,6-bisphosphate; in Streptococcus pyogenes there are two paralogs of tagatose-bisphosphate aldolase, encoded by lacD1 and lacD2; expression of lacD1 is highly regulated by environmental conditions while lacD2 specializes in an efficient utilization of carbohydrate sources; tagatose 1,6-diphosphate aldolase 1078988 lacD 6217572 lacD Streptococcus pneumoniae CGSP14 tagatose 1,6-diphosphate aldolase YP_001835825.1 1078008 D 516950 CDS YP_001835826.1 182684079 6217562 1079222..1080058 1 NC_010582.1 transcription antiterminator LacT 1080058 lacT 6217562 lacT Streptococcus pneumoniae CGSP14 transcription antiterminator LacT YP_001835826.1 1079222 D 516950 CDS YP_001835827.1 182684080 6217738 1080094..1080411 1 NC_010582.1 PTS system lactose-specific transporter subunit IIA 1080411 6217738 SPCG_1110 Streptococcus pneumoniae CGSP14 PTS system lactose-specific transporter subunit IIA YP_001835827.1 1080094 D 516950 CDS YP_001835828.1 182684081 6217555 1080383..1082107 1 NC_010582.1 PTS system lactose-specific transporter subunit IIBC 1082107 6217555 SPCG_1111 Streptococcus pneumoniae CGSP14 PTS system lactose-specific transporter subunit IIBC YP_001835828.1 1080383 D 516950 CDS YP_001835829.1 182684082 6218043 1082313..1083728 1 NC_010582.1 catalyzes the formation of 6-phospho-galactose from a 6-phospho-beta-galactoside; 6-phospho-beta-galactosidase 1083728 lacG 6218043 lacG Streptococcus pneumoniae CGSP14 6-phospho-beta-galactosidase YP_001835829.1 1082313 D 516950 CDS YP_001835830.1 182684083 6217734 1083771..1084028 1 NC_010582.1 hypothetical protein 1084028 6217734 SPCG_1113 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835830.1 1083771 D 516950 CDS YP_001835831.1 182684084 6217601 complement(1084307..1085068) 1 NC_010582.1 lactose phosphotransferase system repressor 1085068 lacR 6217601 lacR Streptococcus pneumoniae CGSP14 lactose phosphotransferase system repressor YP_001835831.1 1084307 R 516950 CDS YP_001835832.1 182684085 6217913 1085378..1085896 1 NC_010582.1 degenerate transposase 1085896 6217913 SPCG_1115 Streptococcus pneumoniae CGSP14 degenerate transposase YP_001835832.1 1085378 D 516950 CDS YP_001835833.1 182684086 6218554 1086177..1086704 1 NC_010582.1 degenerate transposase 1086704 6218554 SPCG_1116 Streptococcus pneumoniae CGSP14 degenerate transposase YP_001835833.1 1086177 D 516950 CDS YP_001835834.1 182684087 6217125 complement(1086742..1087704) 1 NC_010582.1 B2 or R2 protein; type 1b enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdE; ribonucleotide-diphosphate reductase subunit beta 1087704 nrdF 6217125 nrdF Streptococcus pneumoniae CGSP14 ribonucleotide-diphosphate reductase subunit beta YP_001835834.1 1086742 R 516950 CDS YP_001835835.1 182684088 6218446 complement(1087892..1090051) 1 NC_010582.1 Catalyzes the rate-limiting step in dNTP synthesis; ribonucleotide-diphosphate reductase subunit alpha 1090051 nrdE 6218446 nrdE Streptococcus pneumoniae CGSP14 ribonucleotide-diphosphate reductase subunit alpha YP_001835835.1 1087892 R 516950 CDS YP_001835836.1 182684089 6217602 complement(1090132..1090368) 1 NC_010582.1 nrdH-redoxin 1090368 nrdH 6217602 nrdH Streptococcus pneumoniae CGSP14 nrdH-redoxin YP_001835836.1 1090132 R 516950 CDS YP_001835837.1 182684090 6218429 1090701..1090964 1 NC_010582.1 phosphocarrier protein HPr 1090964 6218429 SPCG_1120 Streptococcus pneumoniae CGSP14 phosphocarrier protein HPr YP_001835837.1 1090701 D 516950 CDS YP_001835838.1 182684091 6217847 1090970..1092703 1 NC_010582.1 phosphoenolpyruvate-protein phosphotransferase 1092703 6217847 SPCG_1121 Streptococcus pneumoniae CGSP14 phosphoenolpyruvate-protein phosphotransferase YP_001835838.1 1090970 D 516950 CDS YP_001835839.1 182684092 6217757 1092922..1095480 1 NC_010582.1 hypothetical protein 1095480 6217757 SPCG_1122 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835839.1 1092922 D 516950 CDS YP_001835840.1 182684093 6217888 1095622..1095996 1 NC_010582.1 hypothetical protein 1095996 6217888 SPCG_1123 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835840.1 1095622 D 516950 CDS YP_001835841.1 182684094 6217846 1096072..1096284 1 NC_010582.1 degenerate transposase 1096284 6217846 SPCG_1124 Streptococcus pneumoniae CGSP14 degenerate transposase YP_001835841.1 1096072 D 516950 CDS YP_001835842.1 182684095 6218008 1096449..1097387 1 NC_010582.1 hypothetical protein 1097387 6218008 SPCG_1125 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835842.1 1096449 D 516950 CDS YP_001835843.1 182684096 6217868 1097409..1098161 1 NC_010582.1 HAD superfamily hydrolase 1098161 6217868 SPCG_1126 Streptococcus pneumoniae CGSP14 HAD superfamily hydrolase YP_001835843.1 1097409 D 516950 CDS YP_001835844.1 182684097 6218528 1098219..1098821 1 NC_010582.1 hypothetical protein 1098821 6218528 SPCG_1127 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835844.1 1098219 D 516950 CDS YP_001835845.1 182684098 6216469 1098942..1099610 1 NC_010582.1 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine; uracil-DNA glycosylase 1099610 ung 6216469 ung Streptococcus pneumoniae CGSP14 uracil-DNA glycosylase YP_001835845.1 1098942 D 516950 CDS YP_001835846.1 182684099 6218513 1099620..1100084 1 NC_010582.1 mutator MutT protein 1100084 mutX 6218513 mutX Streptococcus pneumoniae CGSP14 mutator MutT protein YP_001835846.1 1099620 D 516950 CDS YP_001835847.1 182684100 6218589 1100097..1101365 1 NC_010582.1 catalyzes the formation of N-carbamoyl-L-aspartate from (S)-dihydroorotate in pyrimidine biosynthesis; dihydroorotase 1101365 pyrC 6218589 pyrC Streptococcus pneumoniae CGSP14 dihydroorotase YP_001835847.1 1100097 D 516950 CDS YP_001835848.1 182684101 6216840 1101650..1103011 1 NC_010582.1 MATE efflux family protein 1103011 6216840 SPCG_1131 Streptococcus pneumoniae CGSP14 MATE efflux family protein YP_001835848.1 1101650 D 516950 CDS YP_001835849.1 182684102 6217311 complement(1103008..1103118) 1 NC_010582.1 hypothetical protein 1103118 6217311 SPCG_1132 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835849.1 1103008 R 516950 CDS YP_001835850.1 182684103 6218594 1103165..1104133 1 NC_010582.1 acetoin dehydrogenase, E1 component subunit alpha 1104133 acoA 6218594 acoA Streptococcus pneumoniae CGSP14 acetoin dehydrogenase, E1 component subunit alpha YP_001835850.1 1103165 D 516950 CDS YP_001835851.1 182684104 6216404 1104149..1105141 1 NC_010582.1 acetoin dehydrogenase, E1 component subunit beta 1105141 acoB 6216404 acoB Streptococcus pneumoniae CGSP14 acetoin dehydrogenase, E1 component subunit beta YP_001835851.1 1104149 D 516950 CDS YP_001835852.1 182684105 6217448 1105275..1106402 1 NC_010582.1 unlike PdhC proteins from other organisms, some Mycoplasma lack an N-terminal lipoyl domain; in Mycoplasma hyopneumonia the PdhD proteins contains the lipoyl domain; dihydrolipoamide acetyltransferase 1106402 acoC 6217448 acoC Streptococcus pneumoniae CGSP14 dihydrolipoamide acetyltransferase YP_001835852.1 1105275 D 516950 CDS YP_001835853.1 182684106 6218078 1106448..1108151 1 NC_010582.1 acetoin dehydrogenase complex, E3 component, dihydrolipoamide dehydrogenase 1108151 acoL 6218078 acoL Streptococcus pneumoniae CGSP14 acetoin dehydrogenase complex, E3 component, dihydrolipoamide dehydrogenase YP_001835853.1 1106448 D 516950 CDS YP_001835854.1 182684107 6218003 1108215..1109204 1 NC_010582.1 lipoate-protein ligase 1109204 6218003 SPCG_1137 Streptococcus pneumoniae CGSP14 lipoate-protein ligase YP_001835854.1 1108215 D 516950 CDS YP_001835855.1 182684108 6217460 complement(1109269..1110339) 1 NC_010582.1 site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; cell division protein FtsK may regulate the XerS; site-specific tyrosine recombinase XerS 1110339 xerS 6217460 xerS Streptococcus pneumoniae CGSP14 site-specific tyrosine recombinase XerS YP_001835855.1 1109269 R 516950 CDS YP_001835856.1 182684109 6216815 complement(1110923..1112488) 1 NC_010582.1 voltage-gated chloride channel family protein 1112488 6216815 SPCG_1139 Streptococcus pneumoniae CGSP14 voltage-gated chloride channel family protein YP_001835856.1 1110923 R 516950 CDS YP_001835857.1 182684110 6217669 complement(1112489..1113268) 1 NC_010582.1 RNH2; RNase HII; binds manganese; endonuclease which specifically degrades the RNA of RNA-DNA hybrids; ribonuclease HII 1113268 rnhB 6217669 rnhB Streptococcus pneumoniae CGSP14 ribonuclease HII YP_001835857.1 1112489 R 516950 CDS YP_001835858.1 182684111 6217967 complement(1113255..1114106) 1 NC_010582.1 essential GTPase; functions in ribosome assembly; binds a unique part of the 23S rRNA; interacts with ribosomal protein L25(Ctc); ribosomal biogenesis GTPase 1114106 rbgA 6217967 rbgA Streptococcus pneumoniae CGSP14 ribosomal biogenesis GTPase YP_001835858.1 1113255 R 516950 CDS YP_001835859.1 182684112 6216430 complement(1114351..1119834) 1 NC_010582.1 zinc metalloprotease ZmpD 1119834 zmpD 6216430 zmpD Streptococcus pneumoniae CGSP14 zinc metalloprotease ZmpD YP_001835859.1 1114351 R 516950 CDS YP_001835860.1 182684113 6216375 complement(1119878..1125604) 1 NC_010582.1 immunoglobulin A1 protease 1125604 iga 6216375 iga Streptococcus pneumoniae CGSP14 immunoglobulin A1 protease YP_001835860.1 1119878 R 516950 CDS YP_001835861.1 182684114 6216334 complement(1125813..1126991) 1 NC_010582.1 hypothetical protein 1126991 6216334 SPCG_1144 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835861.1 1125813 R 516950 CDS YP_001835862.1 182684115 6216435 complement(1127161..1130811) 1 NC_010582.1 exonuclease RexA 1130811 rexA 6216435 rexA Streptococcus pneumoniae CGSP14 exonuclease RexA YP_001835862.1 1127161 R 516950 CDS YP_001835863.1 182684116 6217021 complement(1130808..1134110) 1 NC_010582.1 exonuclease RexB 1134110 rexB 6217021 rexB Streptococcus pneumoniae CGSP14 exonuclease RexB YP_001835863.1 1130808 R 516950 CDS YP_001835864.1 182684117 6218378 1134591..1134938 1 NC_010582.1 IS630-Spn1, transposase Orf1 1134938 6218378 SPCG_1147 Streptococcus pneumoniae CGSP14 IS630-Spn1, transposase Orf1 YP_001835864.1 1134591 D 516950 CDS YP_001835865.1 182684118 6216330 1135487..1136005 1 NC_010582.1 degenerate transposase 1136005 6216330 SPCG_1148 Streptococcus pneumoniae CGSP14 degenerate transposase YP_001835865.1 1135487 D 516950 CDS YP_001835866.1 182684119 6218377 1136286..1136813 1 NC_010582.1 degenerate transposase 1136813 6218377 SPCG_1149 Streptococcus pneumoniae CGSP14 degenerate transposase YP_001835866.1 1136286 D 516950 CDS YP_001835867.1 182684120 6216438 complement(1136988..1138292) 1 NC_010582.1 enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis; phosphopyruvate hydratase 1138292 eno 6216438 eno Streptococcus pneumoniae CGSP14 phosphopyruvate hydratase YP_001835867.1 1136988 R 516950 CDS YP_001835868.1 182684121 6217839 1138456..1138902 1 NC_010582.1 hypothetical protein 1138902 6217839 SPCG_1151 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835868.1 1138456 D 516950 CDS YP_001835869.1 182684122 6217725 complement(1138899..1139228) 1 NC_010582.1 hypothetical protein 1139228 6217725 SPCG_1152 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835869.1 1138899 R 516950 CDS YP_001835870.1 182684123 6217563 complement(1139197..1140027) 1 NC_010582.1 hypothetical protein 1140027 6217563 SPCG_1153 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835870.1 1139197 R 516950 CDS YP_001835871.1 182684124 6217522 complement(1140024..1140182) 1 NC_010582.1 phosphoserine phosphatase, truncation 1140182 6217522 SPCG_1154 Streptococcus pneumoniae CGSP14 phosphoserine phosphatase, truncation YP_001835871.1 1140024 R 516950 CDS YP_001835872.1 182684125 6218021 complement(1140297..1140668) 1 NC_010582.1 phosphoserine phosphatase 1140668 6218021 SPCG_1155 Streptococcus pneumoniae CGSP14 phosphoserine phosphatase YP_001835872.1 1140297 R 516950 CDS YP_001835873.1 182684126 6217708 complement(1140727..1142160) 1 NC_010582.1 catalyzes the formation of alpha-1,4-glucan chains from ADP-glucose; glycogen synthase 1142160 glgA 6217708 glgA Streptococcus pneumoniae CGSP14 glycogen synthase YP_001835873.1 1140727 R 516950 CDS YP_001835874.1 182684127 6218564 complement(1142157..1143296) 1 NC_010582.1 glycogen biosynthesis protein GlgD 1143296 glgD 6218564 glgD Streptococcus pneumoniae CGSP14 glycogen biosynthesis protein GlgD YP_001835874.1 1142157 R 516950 CDS YP_001835875.1 182684128 6216341 complement(1143286..1144428) 1 NC_010582.1 catalyzes the formation of ADP-glucose and diphosphate from ATP and alpha-D-glucose 1-phosphate; glucose-1-phosphate adenylyltransferase 1144428 glgC 6216341 glgC Streptococcus pneumoniae CGSP14 glucose-1-phosphate adenylyltransferase YP_001835875.1 1143286 R 516950 CDS YP_001835876.1 182684129 6216383 complement(1144418..1146346) 1 NC_010582.1 catalyzes the transfer of a segment of a 1,4-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain; glycogen branching protein 1146346 glgB 6216383 glgB Streptococcus pneumoniae CGSP14 glycogen branching protein YP_001835876.1 1144418 R 516950 CDS YP_001835877.1 182684130 6218563 complement(1146795..1148219) 1 NC_010582.1 glyceraldehyde-3-phosphate dehydrogenase 1148219 gapN 6218563 gapN Streptococcus pneumoniae CGSP14 glyceraldehyde-3-phosphate dehydrogenase YP_001835877.1 1146795 R 516950 CDS YP_001835878.1 182684131 6218402 complement(1148551..1148712) 1 NC_010582.1 hypothetical protein 1148712 6218402 SPCG_1161 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835878.1 1148551 R 516950 CDS YP_001835879.1 182684132 6216432 complement(1148763..1151042) 1 NC_010582.1 pullulanase 1151042 pulI 6216432 pulI Streptococcus pneumoniae CGSP14 pullulanase YP_001835879.1 1148763 R 516950 CDS YP_001835880.1 182684133 6216373 complement(1151154..1153112) 1 NC_010582.1 this protein catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction; essential for DNA replication and repair of damaged DNA; similar to ligase LigB; NAD-dependent DNA ligase LigA 1153112 ligA 6216373 ligA Streptococcus pneumoniae CGSP14 NAD-dependent DNA ligase LigA YP_001835880.1 1151154 R 516950 CDS YP_001835881.1 182684134 6216364 complement(1153205..1154383) 1 NC_010582.1 transporter 1154383 6216364 SPCG_1164 Streptococcus pneumoniae CGSP14 transporter YP_001835881.1 1153205 R 516950 CDS YP_001835882.1 182684135 6217858 complement(1154463..1154555) 1 NC_010582.1 hypothetical protein 1154555 6217858 SPCG_1165 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835882.1 1154463 R 516950 CDS YP_001835883.1 182684136 6217524 complement(1154689..1155339) 1 NC_010582.1 hypothetical protein 1155339 6217524 SPCG_1166 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835883.1 1154689 R 516950 CDS YP_001835884.1 182684137 6217642 complement(1155312..1157213) 1 NC_010582.1 ABC transporter ATP-binding protein 1157213 6217642 SPCG_1167 Streptococcus pneumoniae CGSP14 ABC transporter ATP-binding protein YP_001835884.1 1155312 R 516950 CDS YP_001835885.1 182684138 6217382 complement(1157643..1157918) 1 NC_010582.1 DNA-binding protein HU 1157918 hlpA 6217382 hlpA Streptococcus pneumoniae CGSP14 DNA-binding protein HU YP_001835885.1 1157643 R 516950 CDS YP_001835886.1 182684139 6217956 complement(1158025..1158864) 1 NC_010582.1 degV family protein 1158864 6217956 SPCG_1169 Streptococcus pneumoniae CGSP14 degV family protein YP_001835886.1 1158025 R 516950 CDS YP_001835887.1 182684140 6218553 1159006..1159854 1 NC_010582.1 hypothetical protein 1159854 6218553 SPCG_1170 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835887.1 1159006 D 516950 CDS YP_001835888.1 182684141 6216394 complement(1159947..1160864) 1 NC_010582.1 catalyzes the formation of FMN from riboflavin and the formation of FAD from FMN; in Bacillus the ribC gene has both flavokinase and FAD synthetase activities; bifunctional riboflavin kinase/FMN adenylyltransferase 1160864 mreA 6216394 mreA Streptococcus pneumoniae CGSP14 bifunctional riboflavin kinase/FMN adenylyltransferase YP_001835888.1 1159947 R 516950 CDS YP_001835889.1 182684142 6216322 1161202..1161330 1 NC_010582.1 hypothetical protein 1161330 6216322 SPCG_1172 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835889.1 1161202 D 516950 CDS YP_001835890.1 182684143 6217289 1161302..1161472 1 NC_010582.1 hypothetical protein 1161472 6217289 SPCG_1173 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835890.1 1161302 D 516950 CDS YP_001835891.1 182684144 6216820 complement(1161818..1162111) 1 NC_010582.1 involved in the peptidyltransferase reaction during translation; 50S ribosomal protein L27 1162111 rpmA 6216820 rpmA Streptococcus pneumoniae CGSP14 50S ribosomal protein L27 YP_001835891.1 1161818 R 516950 CDS YP_001835892.1 182684145 6218577 complement(1162128..1162472) 1 NC_010582.1 hypothetical protein 1162472 6218577 SPCG_1175 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835892.1 1162128 R 516950 CDS YP_001835893.1 182684146 6216433 complement(1162488..1162877) 1 NC_010582.1 50S ribosomal protein L21 1162877 rplU 6216433 rplU Streptococcus pneumoniae CGSP14 50S ribosomal protein L21 YP_001835893.1 1162488 R 516950 CDS YP_001835894.1 182684147 6218559 complement(1162990..1163688) 1 NC_010582.1 hypothetical protein 1163688 6218559 SPCG_1177 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835894.1 1162990 R 516950 CDS YP_001835895.1 182684148 6216384 1164090..1164389 1 NC_010582.1 hypothetical protein 1164389 6216384 SPCG_1178 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835895.1 1164090 D 516950 CDS YP_001835896.1 182684149 6216392 complement(1164730..1165704) 1 NC_010582.1 in Salmonella this enzyme is required for ethanolamine catabolism; has higher affinity for CoA than Pta; phosphotransacetylase 1165704 eutD 6216392 eutD Streptococcus pneumoniae CGSP14 phosphotransacetylase YP_001835896.1 1164730 R 516950 CDS YP_001835897.1 182684150 6218149 complement(1165748..1166644) 1 NC_010582.1 ribosomal large subunit pseudouridine synthase D 1166644 rluD 6218149 rluD Streptococcus pneumoniae CGSP14 ribosomal large subunit pseudouridine synthase D YP_001835897.1 1165748 R 516950 CDS YP_001835898.1 182684151 6217139 complement(1166641..1167471) 1 NC_010582.1 catalyzes the phosphorylation of NAD to NADP; inorganic polyphosphate/ATP-NAD kinase 1167471 ppnK 6217139 ppnK Streptococcus pneumoniae CGSP14 inorganic polyphosphate/ATP-NAD kinase YP_001835898.1 1166641 R 516950 CDS YP_001835899.1 182684152 6218055 complement(1167443..1168114) 1 NC_010582.1 hypothetical protein 1168114 6218055 SPCG_1182 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835899.1 1167443 R 516950 CDS YP_001835900.1 182684153 6218224 1168242..1168811 1 NC_010582.1 hypothetical protein 1168811 6218224 SPCG_1183 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835900.1 1168242 D 516950 CDS YP_001835901.1 182684154 6217859 1168924..1169883 1 NC_010582.1 catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP; ribose-phosphate pyrophosphokinase 1169883 6217859 SPCG_1184 Streptococcus pneumoniae CGSP14 ribose-phosphate pyrophosphokinase YP_001835901.1 1168924 D 516950 CDS YP_001835902.1 182684155 6216419 1169893..1171008 1 NC_010582.1 class-V aminotransferase 1171008 6216419 SPCG_1185 Streptococcus pneumoniae CGSP14 class-V aminotransferase YP_001835902.1 1169893 D 516950 CDS YP_001835903.1 182684156 6218405 1171013..1171360 1 NC_010582.1 hypothetical protein 1171360 6218405 SPCG_1186 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835903.1 1171013 D 516950 CDS YP_001835904.1 182684157 6216350 1171332..1171583 1 NC_010582.1 hypothetical protein 1171583 6216350 SPCG_1187 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835904.1 1171332 D 516950 CDS YP_001835905.1 182684158 6218411 1171666..1172307 1 NC_010582.1 modulates transcription in response to the NADH/NAD(+) redox state; redox-sensing transcriptional repressor Rex 1172307 6218411 SPCG_1188 Streptococcus pneumoniae CGSP14 redox-sensing transcriptional repressor Rex YP_001835905.1 1171666 D 516950 CDS YP_001835906.1 182684159 6216354 1172325..1173014 1 NC_010582.1 glutamine amidotransferase 1173014 6216354 SPCG_1189 Streptococcus pneumoniae CGSP14 glutamine amidotransferase YP_001835906.1 1172325 D 516950 CDS YP_001835907.1 182684160 6216439 complement(1173011..1173706) 1 NC_010582.1 Involved in DNA double-strand break repair and recombination. Promotes the annealing of complementary single-stranded DNA and by simulation of RAD51 recombinase; DNA repair protein RadC 1173706 radC 6216439 radC Streptococcus pneumoniae CGSP14 DNA repair protein RadC YP_001835907.1 1173011 R 516950 CDS YP_001835908.1 182684161 6216368 complement(1173734..1176025) 1 NC_010582.1 ATP-dependent DNA helicase PcrA 1176025 pcrA 6216368 pcrA Streptococcus pneumoniae CGSP14 ATP-dependent DNA helicase PcrA YP_001835908.1 1173734 R 516950 CDS YP_001835909.1 182684162 6216380 complement(1176216..1176605) 1 NC_010582.1 IS1381 transposase protein B 1176605 6216380 SPCG_1192 Streptococcus pneumoniae CGSP14 IS1381 transposase protein B YP_001835909.1 1176216 R 516950 CDS YP_001835910.1 182684163 6217657 complement(1176631..1176939) 1 NC_010582.1 IS1381 transposase protein A 1176939 6217657 SPCG_1193 Streptococcus pneumoniae CGSP14 IS1381 transposase protein A YP_001835910.1 1176631 R 516950 CDS YP_001835911.1 182684164 6216367 complement(1177401..1178261) 1 NC_010582.1 catalyzes the removal of N-terminal amino acids from peptides and arylamides; methionine aminopeptidase 1178261 map 6216367 map Streptococcus pneumoniae CGSP14 methionine aminopeptidase YP_001835911.1 1177401 R 516950 CDS YP_001835912.1 182684165 6217887 complement(1178277..1179554) 1 NC_010582.1 hypothetical protein 1179554 6217887 SPCG_1195 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835912.1 1178277 R 516950 CDS YP_001835913.1 182684166 6217445 complement(1179547..1180104) 1 NC_010582.1 acetyltransferase 1180104 6217445 SPCG_1196 Streptococcus pneumoniae CGSP14 acetyltransferase YP_001835913.1 1179547 R 516950 CDS YP_001835914.1 182684167 6217143 complement(1180114..1181373) 1 NC_010582.1 adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active; UDP-N-acetylglucosamine 1-carboxyvinyltransferase 1181373 murZ 6217143 murZ Streptococcus pneumoniae CGSP14 UDP-N-acetylglucosamine 1-carboxyvinyltransferase YP_001835914.1 1180114 R 516950 CDS YP_001835915.1 182684168 6218056 1182575..1183093 1 NC_010582.1 degenerate transposase 1183093 6218056 SPCG_1198 Streptococcus pneumoniae CGSP14 degenerate transposase YP_001835915.1 1182575 D 516950 CDS YP_001835916.1 182684169 6216344 1183374..1183901 1 NC_010582.1 degenerate transposase 1183901 6216344 SPCG_1199 Streptococcus pneumoniae CGSP14 degenerate transposase YP_001835916.1 1183374 D 516950 CDS YP_001835917.1 182684170 6216339 complement(1183952..1184110) 1 NC_010582.1 hypothetical protein 1184110 6216339 SPCG_1200 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835917.1 1183952 R 516950 CDS YP_001835918.1 182684171 6217255 complement(1184120..1185430) 1 NC_010582.1 essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication; GTPase ObgE 1185430 obgE 6217255 obgE Streptococcus pneumoniae CGSP14 GTPase ObgE YP_001835918.1 1184120 R 516950 CDS YP_001835919.1 182684172 6218266 complement(1185494..1185628) 1 NC_010582.1 hypothetical protein 1185628 6218266 SPCG_1202 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835919.1 1185494 R 516950 CDS YP_001835920.1 182684173 6216405 complement(1185687..1185863) 1 NC_010582.1 hypothetical protein 1185863 6216405 SPCG_1203 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835920.1 1185687 R 516950 CDS YP_001835921.1 182684174 6218400 complement(1185894..1187219) 1 NC_010582.1 group 1 glycosyl transferase 1187219 6218400 SPCG_1204 Streptococcus pneumoniae CGSP14 group 1 glycosyl transferase YP_001835921.1 1185894 R 516950 CDS YP_001835922.1 182684175 6216391 complement(1187235..1188317) 1 NC_010582.1 glycosyl transferase CpoA 1188317 cpoA 6216391 cpoA Streptococcus pneumoniae CGSP14 glycosyl transferase CpoA YP_001835922.1 1187235 R 516950 CDS YP_001835923.1 182684176 6216358 complement(1188393..1188755) 1 NC_010582.1 hypothetical protein 1188755 6216358 SPCG_1206 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835923.1 1188393 R 516950 CDS YP_001835924.1 182684177 6217292 complement(1188736..1189845) 1 NC_010582.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; primary sigma factor of bacterium; RNA polymerase sigma factor RpoD 1189845 rpoD 6217292 rpoD Streptococcus pneumoniae CGSP14 RNA polymerase sigma factor RpoD YP_001835924.1 1188736 R 516950 CDS YP_001835925.1 182684178 6216577 complement(1189848..1191623) 1 NC_010582.1 synthesizes RNA primers at the replication forks; DNA primase 1191623 dnaG 6216577 dnaG Streptococcus pneumoniae CGSP14 DNA primase YP_001835925.1 1189848 R 516950 CDS YP_001835926.1 182684179 6217731 complement(1191698..1192456) 1 NC_010582.1 ABC transporter ATP-binding protein 1192456 6217731 SPCG_1209 Streptococcus pneumoniae CGSP14 ABC transporter ATP-binding protein YP_001835926.1 1191698 R 516950 CDS YP_001835927.1 182684180 6217556 complement(1192453..1193319) 1 NC_010582.1 hypothetical protein 1193319 6217556 SPCG_1210 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835927.1 1192453 R 516950 CDS YP_001835928.1 182684181 6217971 complement(1193388..1194422) 1 NC_010582.1 hypothetical protein 1194422 6217971 SPCG_1211 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835928.1 1193388 R 516950 CDS YP_001835929.1 182684182 6217481 complement(1194805..1197501) 1 NC_010582.1 catalyzes the formation of oxaloacetate from phosphoenolpyruvate; phosphoenolpyruvate carboxylase 1197501 ppc 6217481 ppc Streptococcus pneumoniae CGSP14 phosphoenolpyruvate carboxylase YP_001835929.1 1194805 R 516950 CDS YP_001835930.1 182684183 6217957 complement(1197521..1198750) 1 NC_010582.1 cell division protein FtsW 1198750 ftsW 6217957 ftsW Streptococcus pneumoniae CGSP14 cell division protein FtsW YP_001835930.1 1197521 R 516950 CDS YP_001835931.1 182684184 6217100 complement(1199013..1199207) 1 NC_010582.1 IS1381 transposase protein A, truncation 1199207 6217100 SPCG_1214 Streptococcus pneumoniae CGSP14 IS1381 transposase protein A, truncation YP_001835931.1 1199013 R 516950 CDS YP_001835932.1 182684185 6218130 complement(1199312..1199644) 1 NC_010582.1 hypothetical protein 1199644 6218130 SPCG_1215 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835932.1 1199312 R 516950 CDS YP_001835933.1 182684186 6217548 complement(1199830..1200438) 1 NC_010582.1 hypothetical protein 1200438 6217548 SPCG_1216 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835933.1 1199830 R 516950 CDS YP_001835934.1 182684187 6217318 complement(1200522..1202315) 1 NC_010582.1 resolvase family site-specific recombinase 1202315 6217318 SPCG_1217 Streptococcus pneumoniae CGSP14 resolvase family site-specific recombinase YP_001835934.1 1200522 R 516950 CDS YP_001835935.1 182684188 6217061 complement(1202765..1202968) 1 NC_010582.1 hypothetical protein 1202968 6217061 SPCG_1218 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835935.1 1202765 R 516950 CDS YP_001835936.1 182684189 6217585 1203392..1203607 1 NC_010582.1 degenerate transposase 1203607 6217585 SPCG_1219 Streptococcus pneumoniae CGSP14 degenerate transposase YP_001835936.1 1203392 D 516950 CDS YP_001835937.1 182684190 6217711 1203732..1204106 1 NC_010582.1 degenerate transposase 1204106 6217711 SPCG_1220 Streptococcus pneumoniae CGSP14 degenerate transposase YP_001835937.1 1203732 D 516950 CDS YP_001835938.1 182684191 6217182 1204091..1204411 1 NC_010582.1 degenerate transposase 1204411 6217182 SPCG_1221 Streptococcus pneumoniae CGSP14 degenerate transposase YP_001835938.1 1204091 D 516950 CDS YP_001835939.1 182684192 6217718 complement(1205044..1205829) 1 NC_010582.1 hypothetical protein 1205829 6217718 SPCG_1222 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835939.1 1205044 R 516950 CDS YP_001835940.1 182684193 6218122 complement(1206088..1206699) 1 NC_010582.1 daunorubicin resistance transmembrane protein 1206699 6218122 SPCG_1223 Streptococcus pneumoniae CGSP14 daunorubicin resistance transmembrane protein YP_001835940.1 1206088 R 516950 CDS YP_001835941.1 182684194 6218001 complement(1206650..1207234) 1 NC_010582.1 hypothetical protein 1207234 6218001 SPCG_1224 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835941.1 1206650 R 516950 CDS YP_001835942.1 182684195 6217690 complement(1207295..1207504) 1 NC_010582.1 hypothetical protein 1207504 6217690 SPCG_1225 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835942.1 1207295 R 516950 CDS YP_001835943.1 182684196 6218385 complement(1208658..1209449) 1 NC_010582.1 hypothetical protein 1209449 6218385 SPCG_1226 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835943.1 1208658 R 516950 CDS YP_001835944.1 182684197 6217515 complement(1209526..1211163) 1 NC_010582.1 methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content; methionyl-tRNA synthetase 1211163 6217515 SPCG_1227 Streptococcus pneumoniae CGSP14 methionyl-tRNA synthetase YP_001835944.1 1209526 R 516950 CDS YP_001835945.1 182684198 6218500 complement(1211231..1211905) 1 NC_010582.1 chloramphenicol acetyltransferase 1211905 6218500 SPCG_1228 Streptococcus pneumoniae CGSP14 chloramphenicol acetyltransferase YP_001835945.1 1211231 R 516950 CDS YP_001835946.1 182684199 6218469 1212706..1213704 1 NC_010582.1 IS1239 transposase 1213704 6218469 SPCG_1229 Streptococcus pneumoniae CGSP14 IS1239 transposase YP_001835946.1 1212706 D 516950 CDS YP_001835947.1 182684200 6216401 complement(1214276..1215136) 1 NC_010582.1 DNA processing protein DprA 1215136 6216401 SPCG_1230 Streptococcus pneumoniae CGSP14 DNA processing protein DprA YP_001835947.1 1214276 R 516950 CDS YP_001835948.1 182684201 6218457 complement(1215220..1215909) 1 NC_010582.1 licC protein 1215909 6218457 SPCG_1231 Streptococcus pneumoniae CGSP14 licC protein YP_001835948.1 1215220 R 516950 CDS YP_001835949.1 182684202 6217770 complement(1215921..1216811) 1 NC_010582.1 licB protein 1216811 6217770 SPCG_1232 Streptococcus pneumoniae CGSP14 licB protein YP_001835949.1 1215921 R 516950 CDS YP_001835950.1 182684203 6216351 complement(1216789..1217658) 1 NC_010582.1 choline kinase 1217658 pck 6216351 pck Streptococcus pneumoniae CGSP14 choline kinase YP_001835950.1 1216789 R 516950 CDS YP_001835951.1 182684204 6217767 complement(1217675..1218715) 1 NC_010582.1 zinc-containing alcohol dehydrogenase 1218715 6217767 SPCG_1234 Streptococcus pneumoniae CGSP14 zinc-containing alcohol dehydrogenase YP_001835951.1 1217675 R 516950 CDS YP_001835952.1 182684205 6218432 complement(1218702..1219409) 1 NC_010582.1 4-diphosphocytidyl-2C-methyl-D-erythritol synthase; MEP cytidylyltransferase; MCT; catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate; involved in isoprenoid and isopentenyl-PP biosynthesis; forms homodimers; 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 1219409 ispD 6218432 ispD Streptococcus pneumoniae CGSP14 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase YP_001835952.1 1218702 R 516950 CDS YP_001835953.1 182684206 6217745 1219745..1221232 1 NC_010582.1 polysaccharide biosynthesis protein 1221232 6217745 SPCG_1236 Streptococcus pneumoniae CGSP14 polysaccharide biosynthesis protein YP_001835953.1 1219745 D 516950 CDS YP_001835954.1 182684207 6217124 1221242..1222045 1 NC_010582.1 licD1 protein 1222045 licD1 6217124 licD1 Streptococcus pneumoniae CGSP14 licD1 protein YP_001835954.1 1221242 D 516950 CDS YP_001835955.1 182684208 6218524 1222014..1222856 1 NC_010582.1 licD2 protein 1222856 licD2 6218524 licD2 Streptococcus pneumoniae CGSP14 licD2 protein YP_001835955.1 1222014 D 516950 CDS YP_001835956.1 182684209 6218082 complement(1223131..1226307) 1 NC_010582.1 four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate; CarB is responsible for the amidotransferase activity; carbamoyl phosphate synthase large subunit 1226307 carB 6218082 carB Streptococcus pneumoniae CGSP14 carbamoyl phosphate synthase large subunit YP_001835956.1 1223131 R 516950 CDS YP_001835957.1 182684210 6218083 complement(1226620..1227699) 1 NC_010582.1 catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers; carbamoyl phosphate synthase small subunit 1227699 carA 6218083 carA Streptococcus pneumoniae CGSP14 carbamoyl phosphate synthase small subunit YP_001835957.1 1226620 R 516950 CDS YP_001835958.1 182684211 6217747 complement(1227749..1228672) 1 NC_010582.1 catalyzes the transfer of the carbamoyl moiety from carbamoyl phosphate to L- aspartate in pyrimidine biosynthesis; aspartate carbamoyltransferase catalytic subunit 1228672 pyrB 6217747 pyrB Streptococcus pneumoniae CGSP14 aspartate carbamoyltransferase catalytic subunit YP_001835958.1 1227749 R 516950 CDS YP_001835959.1 182684212 6218416 complement(1228691..1229212) 1 NC_010582.1 regulates pyrimidine biosynthesis by binding to the mRNA of the pyr genes, also has been shown to have uracil phosphoribosyltransferase activity; bifunctional pyrimidine regulatory protein PyrR/uracil phosphoribosyltransferase 1229212 pyrR 6218416 pyrR Streptococcus pneumoniae CGSP14 bifunctional pyrimidine regulatory protein PyrR/uracil phosphoribosyltransferase YP_001835959.1 1228691 R 516950 CDS YP_001835960.1 182684213 6216398 complement(1229423..1230052) 1 NC_010582.1 endonuclease III 1230052 nth 6216398 nth Streptococcus pneumoniae CGSP14 endonuclease III YP_001835960.1 1229423 R 516950 CDS YP_001835961.1 182684214 6218431 complement(1230052..1230594) 1 NC_010582.1 hypothetical protein 1230594 6218431 SPCG_1244 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835961.1 1230052 R 516950 CDS YP_001835962.1 182684215 6218438 1231320..1232879 1 NC_010582.1 ABC transporter ATP-binding protein 1232879 6218438 SPCG_1245 Streptococcus pneumoniae CGSP14 ABC transporter ATP-binding protein YP_001835962.1 1231320 D 516950 CDS YP_001835963.1 182684216 6216338 complement(1233028..1233936) 1 NC_010582.1 metalloprotease; heat shock protein HtpX 1233936 htpX 6216338 htpX Streptococcus pneumoniae CGSP14 heat shock protein HtpX YP_001835963.1 1233028 R 516950 CDS YP_001835964.1 182684217 6218376 complement(1233929..1234489) 1 NC_010582.1 hypothetical protein 1234489 lemA 6218376 lemA Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835964.1 1233929 R 516950 CDS YP_001835965.1 182684218 6218399 1234559..1235296 1 NC_010582.1 glucose-inhibited division protein B; SAM-dependent methyltransferase; methylates the N7 position of guanosine in position 527 of 16S rRNA; 16S rRNA methyltransferase GidB 1235296 gidB 6218399 gidB Streptococcus pneumoniae CGSP14 16S rRNA methyltransferase GidB YP_001835965.1 1234559 D 516950 CDS YP_001835966.1 182684219 6218436 1235612..1236931 1 NC_010582.1 uracil permease 1236931 pyrP 6218436 pyrP Streptococcus pneumoniae CGSP14 uracil permease YP_001835966.1 1235612 D 516950 CDS YP_001835967.1 182684220 6218510 complement(1237126..1238697) 1 NC_010582.1 signal recognition particle protein 1238697 ffh 6218510 ffh Streptococcus pneumoniae CGSP14 signal recognition particle protein YP_001835967.1 1237126 R 516950 CDS YP_001835968.1 182684221 6218516 complement(1238709..1239041) 1 NC_010582.1 DNA-binding protein 1239041 6218516 SPCG_1251 Streptococcus pneumoniae CGSP14 DNA-binding protein YP_001835968.1 1238709 R 516950 CDS YP_001835969.1 182684223 6218474 complement(1239132..1239509) 1 NC_010582.1 hypothetical protein 1239509 6218474 SPCG_1252 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835969.1 1239132 R 516950 CDS YP_001835970.1 182684222 6218587 1239485..1240885 1 NC_010582.1 hypothetical protein 1240885 6218587 SPCG_1253 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835970.1 1239485 D 516950 CDS YP_001835971.1 182684224 6218440 1240898..1241704 1 NC_010582.1 Cof family protein 1241704 6218440 SPCG_1254 Streptococcus pneumoniae CGSP14 Cof family protein YP_001835971.1 1240898 D 516950 CDS YP_001835972.1 182684225 6218397 complement(1241915..1243690) 1 NC_010582.1 hypothetical protein 1243690 6218397 SPCG_1255 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835972.1 1241915 R 516950 CDS YP_001835973.1 182684226 6216581 complement(1244176..1245357) 1 NC_010582.1 choline binding protein PcpA 1245357 6216581 SPCG_1256 Streptococcus pneumoniae CGSP14 choline binding protein PcpA YP_001835973.1 1244176 R 516950 CDS YP_001835974.1 182684227 6217494 complement(1245370..1246590) 1 NC_010582.1 surface protein A 1246590 6217494 SPCG_1257 Streptococcus pneumoniae CGSP14 surface protein A YP_001835974.1 1245370 R 516950 CDS YP_001835975.1 182684228 6216366 1246618..1247538 1 NC_010582.1 rgg protein 1247538 6216366 SPCG_1258 Streptococcus pneumoniae CGSP14 rgg protein YP_001835975.1 1246618 D 516950 CDS YP_001835976.1 182684229 6216349 complement(1247770..1247991) 1 NC_010582.1 hypothetical protein 1247991 6216349 SPCG_1259 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835976.1 1247770 R 516950 CDS YP_001835977.1 182684230 6216568 complement(1248218..1248565) 1 NC_010582.1 this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site; 50S ribosomal protein L19 1248565 rplS 6216568 rplS Streptococcus pneumoniae CGSP14 50S ribosomal protein L19 YP_001835977.1 1248218 R 516950 CDS YP_001835978.1 182684231 6216355 complement(1248684..1249013) 1 NC_010582.1 may be involved in chromosome condensation; overexpression in Escherichia coli protects against decondensation by camphor; overexpressing the protein results in an increase in supercoiling; camphor resistance protein CrcB 1249013 crcB 6216355 crcB Streptococcus pneumoniae CGSP14 camphor resistance protein CrcB YP_001835978.1 1248684 R 516950 CDS YP_001835979.1 182684232 6217756 complement(1249007..1249381) 1 NC_010582.1 may be involved in chromosome condensation; overexpression in Escherichia coli protects against decondensation by camphor; overexpressing the protein results in an increase in supercoiling; camphor resistance protein CrcB 1249381 crcB 6217756 crcB Streptococcus pneumoniae CGSP14 camphor resistance protein CrcB YP_001835979.1 1249007 R 516950 CDS YP_001835980.1 182684233 6217577 complement(1249378..1249644) 1 NC_010582.1 hypothetical protein 1249644 6217577 SPCG_1263 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835980.1 1249378 R 516950 CDS YP_001835981.1 182684234 6217870 complement(1249760..1250203) 1 NC_010582.1 An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group; flavodoxin 1250203 flaV 6217870 flaV Streptococcus pneumoniae CGSP14 flavodoxin YP_001835981.1 1249760 R 516950 CDS YP_001835982.1 182684235 6217587 1250295..1251242 1 NC_010582.1 DHH subfamily 1 protein 1251242 6217587 SPCG_1265 Streptococcus pneumoniae CGSP14 DHH subfamily 1 protein YP_001835982.1 1250295 D 516950 CDS YP_001835983.1 182684236 6217381 1251296..1251580 1 NC_010582.1 50S ribosomal protein L31 1251580 rpmE 6217381 rpmE Streptococcus pneumoniae CGSP14 50S ribosomal protein L31 YP_001835983.1 1251296 D 516950 CDS YP_001835984.1 182684237 6216600 complement(1251637..1252242) 1 NC_010582.1 hypothetical protein 1252242 6216600 SPCG_1267 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835984.1 1251637 R 516950 CDS YP_001835985.1 182684238 6218452 complement(1252190..1253194) 1 NC_010582.1 hypothetical protein 1253194 6218452 SPCG_1268 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835985.1 1252190 R 516950 CDS YP_001835986.1 182684239 6217451 complement(1253246..1253368) 1 NC_010582.1 hypothetical protein 1253368 6217451 SPCG_1269 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835986.1 1253246 R 516950 CDS YP_001835987.1 182684240 6216417 complement(1253365..1253499) 1 NC_010582.1 hypothetical protein 1253499 6216417 SPCG_1270 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835987.1 1253365 R 516950 CDS YP_001835988.1 182684241 6216382 complement(1253749..1253844) 1 NC_010582.1 hypothetical protein 1253844 6216382 SPCG_1271 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835988.1 1253749 R 516950 CDS YP_001835989.1 182684242 6218579 1254186..1255532 1 NC_010582.1 converts 2-oxoglutarate to glutamate; in Escherichia coli this enzyme plays a role in glutamate synthesis when the cell is under energy restriction; uses NADPH; forms a homohexamer; glutamate dehydrogenase 1255532 gdhA 6218579 gdhA Streptococcus pneumoniae CGSP14 glutamate dehydrogenase YP_001835989.1 1254186 D 516950 CDS YP_001835990.1 182684243 6217612 complement(1255821..1259432) 1 NC_010582.1 glutamate dehydrogenase 1259432 6217612 SPCG_1273 Streptococcus pneumoniae CGSP14 glutamate dehydrogenase YP_001835990.1 1255821 R 516950 CDS YP_001835991.1 182684244 6216340 complement(1259712..1260899) 1 NC_010582.1 site-specific recombinase 1260899 6216340 SPCG_1274 Streptococcus pneumoniae CGSP14 site-specific recombinase YP_001835991.1 1259712 R 516950 CDS YP_001835992.1 182684245 6218359 complement(1260871..1261179) 1 NC_010582.1 hypothetical protein 1261179 6218359 SPCG_1275 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835992.1 1260871 R 516950 CDS YP_001835993.1 182684246 6216347 complement(1261741..1263570) 1 NC_010582.1 Tn5252, relaxase 1263570 6216347 SPCG_1276 Streptococcus pneumoniae CGSP14 Tn5252, relaxase YP_001835993.1 1261741 R 516950 CDS YP_001835994.1 182684247 6218040 complement(1263557..1263922) 1 NC_010582.1 Tn5252, ORF 9 protein 1263922 6218040 SPCG_1277 Streptococcus pneumoniae CGSP14 Tn5252, ORF 9 protein YP_001835994.1 1263557 R 516950 CDS YP_001835995.1 182684248 6217875 complement(1263927..1264283) 1 NC_010582.1 Tn5252, ORF 10 protein 1264283 6217875 SPCG_1278 Streptococcus pneumoniae CGSP14 Tn5252, ORF 10 protein YP_001835995.1 1263927 R 516950 CDS YP_001835996.1 182684249 6218450 complement(1264667..1264921) 1 NC_010582.1 hypothetical protein 1264921 6218450 SPCG_1279 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835996.1 1264667 R 516950 CDS YP_001835997.1 182684250 6216393 complement(1264987..1268991) 1 NC_010582.1 DNA-dependent ATPase I and helicase II 1268991 6216393 SPCG_1280 Streptococcus pneumoniae CGSP14 DNA-dependent ATPase I and helicase II YP_001835997.1 1264987 R 516950 CDS YP_001835998.1 182684251 6216402 complement(1269113..1269499) 1 NC_010582.1 hypothetical protein 1269499 6216402 SPCG_1281 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835998.1 1269113 R 516950 CDS YP_001835999.1 182684252 6217665 complement(1269571..1270521) 1 NC_010582.1 hypothetical protein 1270521 6217665 SPCG_1282 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001835999.1 1269571 R 516950 CDS YP_001836000.1 182684253 6217666 complement(1270606..1271724) 1 NC_010582.1 hypothetical protein 1271724 6217666 SPCG_1283 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836000.1 1270606 R 516950 CDS YP_001836001.1 182684254 6216818 complement(1271986..1273821) 1 NC_010582.1 hypothetical protein 1273821 6216818 SPCG_1284 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836001.1 1271986 R 516950 CDS YP_001836002.1 182684255 6218360 complement(1274199..1274477) 1 NC_010582.1 hypothetical protein 1274477 6218360 SPCG_1285 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836002.1 1274199 R 516950 CDS YP_001836003.1 182684256 6216771 complement(1274452..1275156) 1 NC_010582.1 phosphoserine phosphatase 1275156 6216771 SPCG_1286 Streptococcus pneumoniae CGSP14 phosphoserine phosphatase YP_001836003.1 1274452 R 516950 CDS YP_001836004.1 182684257 6216362 complement(1275209..1275775) 1 NC_010582.1 hypothetical protein 1275775 6216362 SPCG_1287 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836004.1 1275209 R 516950 CDS YP_001836005.1 182684258 6216400 complement(1275868..1276092) 1 NC_010582.1 hypothetical protein 1276092 6216400 SPCG_1288 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836005.1 1275868 R 516950 CDS YP_001836006.1 182684259 6217106 complement(1276181..1276798) 1 NC_010582.1 hypothetical protein 1276798 6217106 SPCG_1289 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836006.1 1276181 R 516950 CDS YP_001836007.1 182684260 6217081 complement(1277120..1277842) 1 NC_010582.1 hypothetical protein 1277842 6217081 SPCG_1290 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836007.1 1277120 R 516950 CDS YP_001836008.1 182684261 6216502 1278159..1279094 1 NC_010582.1 replication initiation protein Rep(RC) 1279094 6216502 SPCG_1291 Streptococcus pneumoniae CGSP14 replication initiation protein Rep(RC) YP_001836008.1 1278159 D 516950 CDS YP_001836009.1 182684262 6217002 complement(1279959..1280609) 1 NC_010582.1 chloramphenicol acetyltransferase 1280609 6217002 SPCG_1292 Streptococcus pneumoniae CGSP14 chloramphenicol acetyltransferase YP_001836009.1 1279959 R 516950 CDS YP_001836010.1 182684263 6216742 complement(1280780..1281028) 1 NC_010582.1 hypothetical protein 1281028 6216742 SPCG_1293 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836010.1 1280780 R 516950 CDS YP_001836011.1 182684264 6217281 complement(1281267..1282055) 1 NC_010582.1 hypothetical protein 1282055 6217281 SPCG_1294 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836011.1 1281267 R 516950 CDS YP_001836012.1 182684265 6216983 complement(1282531..1283289) 1 NC_010582.1 hypothetical protein 1283289 6216983 SPCG_1295 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836012.1 1282531 R 516950 CDS YP_001836013.1 182684266 6216667 complement(1283289..1283765) 1 NC_010582.1 transcriptional regulator 1283765 6216667 SPCG_1296 Streptococcus pneumoniae CGSP14 transcriptional regulator YP_001836013.1 1283289 R 516950 CDS YP_001836014.1 182684267 6217202 complement(1283835..1284107) 1 NC_010582.1 hypothetical protein 1284107 6217202 SPCG_1297 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836014.1 1283835 R 516950 CDS YP_001836015.1 182684268 6216984 complement(1284145..1284528) 1 NC_010582.1 hypothetical protein 1284528 6216984 SPCG_1298 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836015.1 1284145 R 516950 CDS YP_001836016.1 182684269 6216928 complement(1284525..1284758) 1 NC_010582.1 hypothetical protein 1284758 6216928 SPCG_1299 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836016.1 1284525 R 516950 CDS YP_001836017.1 182684270 6216588 complement(1284809..1285894) 1 NC_010582.1 hypothetical protein 1285894 6216588 SPCG_1300 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836017.1 1284809 R 516950 CDS YP_001836018.1 182684271 6216957 complement(1285904..1286545) 1 NC_010582.1 parvulin-like peptidyl-prolyl isomerase 1286545 6216957 SPCG_1301 Streptococcus pneumoniae CGSP14 parvulin-like peptidyl-prolyl isomerase YP_001836018.1 1285904 R 516950 CDS YP_001836019.1 182684272 6217723 1286705..1286902 1 NC_010582.1 hypothetical protein 1286902 6217723 SPCG_1302 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836019.1 1286705 D 516950 CDS YP_001836020.1 182684273 6216569 complement(1286916..1287233) 1 NC_010582.1 hypothetical protein 1287233 6216569 SPCG_1303 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836020.1 1286916 R 516950 CDS YP_001836021.1 182684274 6216974 complement(1287226..1287510) 1 NC_010582.1 hypothetical protein 1287510 6216974 SPCG_1304 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836021.1 1287226 R 516950 CDS YP_001836022.1 182684275 6216480 complement(1287585..1293818) 1 NC_010582.1 SNF2 family protein 1293818 6216480 SPCG_1305 Streptococcus pneumoniae CGSP14 SNF2 family protein YP_001836022.1 1287585 R 516950 CDS YP_001836023.1 182684276 6216491 complement(1293851..1294261) 1 NC_010582.1 hypothetical protein 1294261 6216491 SPCG_1306 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836023.1 1293851 R 516950 CDS YP_001836024.1 182684277 6217030 complement(1294413..1295108) 1 NC_010582.1 hypothetical protein 1295108 6217030 SPCG_1307 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836024.1 1294413 R 516950 CDS YP_001836025.1 182684278 6217029 complement(1295217..1298030) 1 NC_010582.1 hypothetical protein 1298030 6217029 SPCG_1308 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836025.1 1295217 R 516950 CDS YP_001836026.1 182684279 6216883 complement(1298042..1300357) 1 NC_010582.1 hypothetical protein 1300357 6216883 SPCG_1309 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836026.1 1298042 R 516950 CDS YP_001836027.1 182684280 6216921 complement(1300347..1300709) 1 NC_010582.1 hypothetical protein 1300709 6216921 SPCG_1310 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836027.1 1300347 R 516950 CDS YP_001836028.1 182684281 6216778 complement(1300763..1301617) 1 NC_010582.1 hypothetical protein 1301617 6216778 SPCG_1311 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836028.1 1300763 R 516950 CDS YP_001836029.1 182684282 6216920 complement(1301634..1301876) 1 NC_010582.1 hypothetical protein 1301876 6216920 SPCG_1312 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836029.1 1301634 R 516950 CDS YP_001836030.1 182684283 6216847 complement(1301897..1303777) 1 NC_010582.1 hypothetical protein 1303777 6216847 SPCG_1313 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836030.1 1301897 R 516950 CDS YP_001836031.1 182684284 6217016 complement(1303774..1304283) 1 NC_010582.1 hypothetical protein 1304283 6217016 SPCG_1314 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836031.1 1303774 R 516950 CDS YP_001836032.1 182684285 6216514 complement(1304252..1304551) 1 NC_010582.1 hypothetical protein 1304551 6216514 SPCG_1315 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836032.1 1304252 R 516950 CDS YP_001836033.1 182684286 6216959 complement(1304834..1305670) 1 NC_010582.1 hypothetical protein 1305670 6216959 SPCG_1316 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836033.1 1304834 R 516950 CDS YP_001836034.1 182684287 6216555 complement(1305670..1306314) 1 NC_010582.1 hypothetical protein 1306314 6216555 SPCG_1317 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836034.1 1305670 R 516950 CDS YP_001836035.1 182684288 6217263 1306549..1306668 1 NC_010582.1 hypothetical protein 1306668 6217263 SPCG_1318 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836035.1 1306549 D 516950 CDS YP_001836036.1 182684289 6216675 1306691..1307005 1 NC_010582.1 hypothetical protein 1307005 6216675 SPCG_1319 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836036.1 1306691 D 516950 CDS YP_001836037.1 182684290 6216529 1307021..1307407 1 NC_010582.1 hypothetical protein 1307407 6216529 SPCG_1320 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836037.1 1307021 D 516950 CDS YP_001836038.1 182684291 6216663 1307436..1308821 1 NC_010582.1 hypothetical protein 1308821 6216663 SPCG_1321 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836038.1 1307436 D 516950 CDS YP_001836039.1 182684292 6216441 1308999..1310417 1 NC_010582.1 hypothetical protein 1310417 6216441 SPCG_1322 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836039.1 1308999 D 516950 CDS YP_001836040.1 182684293 6216510 1310674..1311459 1 NC_010582.1 erythromycin ribosome methylase 1311459 6216510 SPCG_1323 Streptococcus pneumoniae CGSP14 erythromycin ribosome methylase YP_001836040.1 1310674 D 516950 CDS YP_001836041.1 182684294 6216454 1311797..1312339 1 NC_010582.1 streptothricin acetyltransferase 1312339 6216454 SPCG_1324 Streptococcus pneumoniae CGSP14 streptothricin acetyltransferase YP_001836041.1 1311797 D 516950 CDS YP_001836042.1 182684295 6217078 1312432..1313226 1 NC_010582.1 aminoglycoside phosphotransferase type III 1313226 6217078 SPCG_1325 Streptococcus pneumoniae CGSP14 aminoglycoside phosphotransferase type III YP_001836042.1 1312432 D 516950 CDS YP_001836043.1 182684296 6217077 1314404..1314643 1 NC_010582.1 omega2 protein 1314643 6217077 SPCG_1326 Streptococcus pneumoniae CGSP14 omega2 protein YP_001836043.1 1314404 D 516950 CDS YP_001836044.1 182684297 6217136 1314900..1315637 1 NC_010582.1 rRNA methylase 1315637 6217136 SPCG_1327 Streptococcus pneumoniae CGSP14 rRNA methylase YP_001836044.1 1314900 D 516950 CDS YP_001836045.1 182684298 6217137 1315992..1316546 1 NC_010582.1 resolvase 1316546 6217137 SPCG_1328 Streptococcus pneumoniae CGSP14 resolvase YP_001836045.1 1315992 D 516950 CDS YP_001836046.1 182684299 6216505 1316550..1319468 1 NC_010582.1 transposase 1319468 6216505 SPCG_1329 Streptococcus pneumoniae CGSP14 transposase YP_001836046.1 1316550 D 516950 CDS YP_001836047.1 182684300 6218504 complement(1319524..1319763) 1 NC_010582.1 hypothetical protein 1319763 6218504 SPCG_1330 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836047.1 1319524 R 516950 CDS YP_001836048.1 182684301 6218531 1320259..1320690 1 NC_010582.1 hypothetical protein 1320690 6218531 SPCG_1331 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836048.1 1320259 D 516950 CDS YP_001836049.1 182684302 6218506 1320687..1320917 1 NC_010582.1 hypothetical protein 1320917 6218506 SPCG_1332 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836049.1 1320687 D 516950 CDS YP_001836050.1 182684303 6218526 1321378..1321581 1 NC_010582.1 hypothetical protein 1321581 6218526 SPCG_1333 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836050.1 1321378 D 516950 CDS YP_001836051.1 182684304 6216346 1321663..1322625 1 NC_010582.1 hypothetical protein 1322625 6216346 SPCG_1334 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836051.1 1321663 D 516950 CDS YP_001836052.1 182684305 6216336 1322622..1322879 1 NC_010582.1 hypothetical protein 1322879 6216336 SPCG_1335 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836052.1 1322622 D 516950 CDS YP_001836053.1 182684306 6216414 complement(1323094..1323681) 1 NC_010582.1 hypothetical protein 1323681 6216414 SPCG_1336 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836053.1 1323094 R 516950 CDS YP_001836054.1 182684307 6218536 complement(1323684..1323917) 1 NC_010582.1 hypothetical protein 1323917 6218536 SPCG_1337 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836054.1 1323684 R 516950 CDS YP_001836055.1 182684308 6218537 complement(1324303..1324752) 1 NC_010582.1 hypothetical protein 1324752 6218537 SPCG_1338 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836055.1 1324303 R 516950 CDS YP_001836056.1 182684309 6218492 complement(1324736..1326094) 1 NC_010582.1 type II DNA modification methyltransferase Spn5252IP 1326094 6218492 SPCG_1339 Streptococcus pneumoniae CGSP14 type II DNA modification methyltransferase Spn5252IP YP_001836056.1 1324736 R 516950 CDS YP_001836057.1 182684310 6218447 complement(1326193..1326972) 1 NC_010582.1 replication initiator A, N-terminal 1326972 6218447 SPCG_1340 Streptococcus pneumoniae CGSP14 replication initiator A, N-terminal YP_001836057.1 1326193 R 516950 CDS YP_001836058.1 182684312 6218424 complement(1326969..1327142) 1 NC_010582.1 hypothetical protein 1327142 6218424 SPCG_1341 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836058.1 1326969 R 516950 CDS YP_001836059.1 182684311 6216898 1327118..1327264 1 NC_010582.1 hypothetical protein 1327264 6216898 SPCG_1342 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836059.1 1327118 D 516950 CDS YP_001836060.1 182684313 6218576 1327330..1327731 1 NC_010582.1 50S ribosomal protein L7/L12 1327731 rplL 6218576 rplL Streptococcus pneumoniae CGSP14 50S ribosomal protein L7/L12 YP_001836060.1 1327330 D 516950 CDS YP_001836061.1 182684314 6218422 complement(1327788..1328351) 1 NC_010582.1 binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit; 50S ribosomal protein L10 1328351 rplJ 6218422 rplJ Streptococcus pneumoniae CGSP14 50S ribosomal protein L10 YP_001836061.1 1327788 R 516950 CDS YP_001836062.1 182684315 6216603 complement(1328538..1330004) 1 NC_010582.1 chlorohydrolase 1330004 trzA 6216603 trzA Streptococcus pneumoniae CGSP14 chlorohydrolase YP_001836062.1 1328538 R 516950 CDS YP_001836063.1 182684316 6217777 complement(1330099..1331886) 1 NC_010582.1 ABC transporter ATP-binding protein/permease 1331886 6217777 SPCG_1346 Streptococcus pneumoniae CGSP14 ABC transporter ATP-binding protein/permease YP_001836063.1 1330099 R 516950 CDS YP_001836064.1 182684317 6218596 complement(1331849..1333573) 1 NC_010582.1 ABC transporter ATP-binding protein/permease 1333573 6218596 SPCG_1347 Streptococcus pneumoniae CGSP14 ABC transporter ATP-binding protein/permease YP_001836064.1 1331849 R 516950 CDS YP_001836065.1 182684318 6217516 complement(1333631..1334569) 1 NC_010582.1 bifunctional methionine sulfoxide reductase A/B 1334569 msrA 6217516 msrA Streptococcus pneumoniae CGSP14 bifunctional methionine sulfoxide reductase A/B YP_001836065.1 1333631 R 516950 CDS YP_001836066.1 182684319 6217276 complement(1334864..1335733) 1 NC_010582.1 catalyzes the formation of O-phospho-L-homoserine from L-homoserine in threonine biosynthesis from asparate; homoserine kinase 1335733 thrB 6217276 thrB Streptococcus pneumoniae CGSP14 homoserine kinase YP_001836066.1 1334864 R 516950 CDS YP_001836067.1 182684320 6216328 complement(1335735..1337054) 1 NC_010582.1 catalyzes the formation of L-aspartate 4-semialdehyde from L-homoserine; homoserine dehydrogenase 1337054 hom 6216328 hom Streptococcus pneumoniae CGSP14 homoserine dehydrogenase YP_001836067.1 1335735 R 516950 CDS YP_001836068.1 182684321 6216329 complement(1337172..1337924) 1 NC_010582.1 enables recognition and targeting of proteins for proteolysis, involved in negative regulation of competence; adaptor protein 1337924 mecA 6216329 mecA Streptococcus pneumoniae CGSP14 adaptor protein YP_001836068.1 1337172 R 516950 CDS YP_001836069.1 182684322 6216604 complement(1338051..1339085) 1 NC_010582.1 hypothetical protein 1339085 6216604 SPCG_1352 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836069.1 1338051 R 516950 CDS YP_001836070.1 182684323 6217590 complement(1339114..1340547) 1 NC_010582.1 hypothetical protein 1340547 6217590 SPCG_1353 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836070.1 1339114 R 516950 CDS YP_001836071.1 182684324 6216476 complement(1340563..1341549) 1 NC_010582.1 glycosyl transferase family protein 1341549 6216476 SPCG_1354 Streptococcus pneumoniae CGSP14 glycosyl transferase family protein YP_001836071.1 1340563 R 516950 CDS YP_001836072.1 182684325 6218340 complement(1341551..1342654) 1 NC_010582.1 group 1 glycosyl transferase 1342654 6218340 SPCG_1355 Streptococcus pneumoniae CGSP14 group 1 glycosyl transferase YP_001836072.1 1341551 R 516950 CDS YP_001836073.1 182684326 6218475 complement(1342644..1343489) 1 NC_010582.1 licD3 protein 1343489 licD3 6218475 licD3 Streptococcus pneumoniae CGSP14 licD3 protein YP_001836073.1 1342644 R 516950 CDS YP_001836074.1 182684327 6218555 complement(1343540..1343650) 1 NC_010582.1 hypothetical protein 1343650 6218555 SPCG_1357 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836074.1 1343540 R 516950 CDS YP_001836075.1 182684328 6218030 complement(1343768..1345042) 1 NC_010582.1 psr protein 1345042 6218030 SPCG_1358 Streptococcus pneumoniae CGSP14 psr protein YP_001836075.1 1343768 R 516950 CDS YP_001836076.1 182684329 6216952 complement(1345039..1345887) 1 NC_010582.1 catalyzes the formation of phenylpyruvate from prephenate in phenylalanine biosynthesis; prephenate dehydratase 1345887 pheA 6216952 pheA Streptococcus pneumoniae CGSP14 prephenate dehydratase YP_001836076.1 1345039 R 516950 CDS YP_001836077.1 182684330 6218287 complement(1345884..1346360) 1 NC_010582.1 shikimate kinase 1346360 aroK 6218287 aroK Streptococcus pneumoniae CGSP14 shikimate kinase YP_001836077.1 1345884 R 516950 CDS YP_001836078.1 182684331 6218312 complement(1346353..1347648) 1 NC_010582.1 catalyzes the formation of 5-O-(1-carboxyvinyl)-3-phosphoshikimate from phosphoenolpyruvate and 3-phosphoshikimate in tryptophan biosynthesis; 3-phosphoshikimate 1-carboxyvinyltransferase 1347648 aroA 6218312 aroA Streptococcus pneumoniae CGSP14 3-phosphoshikimate 1-carboxyvinyltransferase YP_001836078.1 1346353 R 516950 CDS YP_001836079.1 182684332 6216377 complement(1347728..1348066) 1 NC_010582.1 hypothetical protein 1348066 6216377 SPCG_1362 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836079.1 1347728 R 516950 CDS YP_001836080.1 182684333 6216335 complement(1348077..1349180) 1 NC_010582.1 catalyzes the formation of 4-hydroxyphenylpyruvate from prephenate; prephenate dehydrogenase 1349180 tyrA 6216335 tyrA Streptococcus pneumoniae CGSP14 prephenate dehydrogenase YP_001836080.1 1348077 R 516950 CDS YP_001836081.1 182684334 6216406 complement(1349190..1350356) 1 NC_010582.1 catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis; chorismate synthase 1350356 aroC 6216406 aroC Streptococcus pneumoniae CGSP14 chorismate synthase YP_001836081.1 1349190 R 516950 CDS YP_001836082.1 182684335 6216411 complement(1350366..1351433) 1 NC_010582.1 catalyzes the formation of 3-dehydroquinate from 3-deoxy-arabino-heptulonate 7-phosphate; functions in aromatic amino acid biosynthesis; 3-dehydroquinate synthase 1351433 aroB 6216411 aroB Streptococcus pneumoniae CGSP14 3-dehydroquinate synthase YP_001836082.1 1350366 R 516950 CDS YP_001836083.1 182684336 6216396 complement(1351452..1352306) 1 NC_010582.1 AroE; catalyzes the conversion of shikimate to 3-dehydroshikimate; shikimate 5-dehydrogenase 1352306 aroE 6216396 aroE Streptococcus pneumoniae CGSP14 shikimate 5-dehydrogenase YP_001836083.1 1351452 R 516950 CDS YP_001836084.1 182684337 6216425 complement(1352296..1352973) 1 NC_010582.1 catalyzes the dehydration of 3-dehydroquinate to form 3-dehydroshikimate in aromatic amino acid biosynthesis; 3-dehydroquinate dehydratase 1352973 aroD 6216425 aroD Streptococcus pneumoniae CGSP14 3-dehydroquinate dehydratase YP_001836084.1 1352296 R 516950 CDS YP_001836085.1 182684338 6218552 complement(1352970..1354142) 1 NC_010582.1 hypothetical protein 1354142 6218552 SPCG_1368 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836085.1 1352970 R 516950 CDS YP_001836086.1 182684339 6218539 complement(1354820..1356481) 1 NC_010582.1 hypothetical protein 1356481 6218539 SPCG_1369 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836086.1 1354820 R 516950 CDS YP_001836087.1 182684340 6218574 complement(1356435..1357250) 1 NC_010582.1 ABC transporter ATP-binding protein 1357250 6218574 SPCG_1370 Streptococcus pneumoniae CGSP14 ABC transporter ATP-binding protein YP_001836087.1 1356435 R 516950 CDS YP_001836088.1 182684341 6218550 1357363..1358817 1 NC_010582.1 converts 1,4-alpha-D-glucans to maltodextrin; alpha-amylase 1358817 amy 6218550 amy Streptococcus pneumoniae CGSP14 alpha-amylase YP_001836088.1 1357363 D 516950 CDS YP_001836089.1 182684342 6218578 complement(1358907..1361525) 1 NC_010582.1 Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; alanyl-tRNA synthetase 1361525 alaS 6218578 alaS Streptococcus pneumoniae CGSP14 alanyl-tRNA synthetase YP_001836089.1 1358907 R 516950 CDS YP_001836090.1 182684343 6218011 complement(1361547..1362044) 1 NC_010582.1 hypothetical protein 1362044 6218011 SPCG_1373 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836090.1 1361547 R 516950 CDS YP_001836091.1 182684344 6218502 complement(1362698..1363768) 1 NC_010582.1 spermidine/putrescine ABC transporter spermidine/putrescine-binding protein 1363768 6218502 SPCG_1374 Streptococcus pneumoniae CGSP14 spermidine/putrescine ABC transporter spermidine/putrescine-binding protein YP_001836091.1 1362698 R 516950 CDS YP_001836092.1 182684345 6218494 complement(1363765..1364565) 1 NC_010582.1 spermidine/putrescine ABC transporter permease 1364565 6218494 SPCG_1375 Streptococcus pneumoniae CGSP14 spermidine/putrescine ABC transporter permease YP_001836092.1 1363765 R 516950 CDS YP_001836093.1 182684346 6218392 complement(1364535..1365362) 1 NC_010582.1 spermidine/putrescine ABC transporter permease 1365362 6218392 SPCG_1376 Streptococcus pneumoniae CGSP14 spermidine/putrescine ABC transporter permease YP_001836093.1 1364535 R 516950 CDS YP_001836094.1 182684347 6216360 complement(1365322..1366479) 1 NC_010582.1 spermidine/putrescine ABC transporter ATP-binding protein 1366479 6216360 SPCG_1377 Streptococcus pneumoniae CGSP14 spermidine/putrescine ABC transporter ATP-binding protein YP_001836094.1 1365322 R 516950 CDS YP_001836095.1 182684348 6217473 complement(1366639..1367544) 1 NC_010582.1 catalyzes the reduction of UDP-N-acetylglucosamine enolpyruvate to form UDP-N-acetylmuramate in peptidoglycan biosynthesis; UDP-N-acetylenolpyruvoylglucosamine reductase 1367544 murB 6217473 murB Streptococcus pneumoniae CGSP14 UDP-N-acetylenolpyruvoylglucosamine reductase YP_001836095.1 1366639 R 516950 CDS YP_001836096.1 182684349 6216470 1367596..1367694 1 NC_010582.1 hypothetical protein 1367694 6216470 SPCG_1379 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836096.1 1367596 D 516950 CDS YP_001836097.1 182684350 6216332 complement(1367658..1368410) 1 NC_010582.1 hypothetical protein 1368410 6216332 SPCG_1380 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836097.1 1367658 R 516950 CDS YP_001836098.1 182684351 6218382 complement(1368420..1369151) 1 NC_010582.1 alpha-acetolactate decarboxylase 1369151 aldB 6218382 aldB Streptococcus pneumoniae CGSP14 alpha-acetolactate decarboxylase YP_001836098.1 1368420 R 516950 CDS YP_001836099.1 182684352 6218430 1369293..1370564 1 NC_010582.1 hypothetical protein 1370564 6218430 SPCG_1382 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836099.1 1369293 D 516950 CDS YP_001836100.1 182684353 6218421 complement(1370584..1371399) 1 NC_010582.1 amino acid ABC transporter amino acid-binding protein 1371399 6218421 SPCG_1383 Streptococcus pneumoniae CGSP14 amino acid ABC transporter amino acid-binding protein YP_001836100.1 1370584 R 516950 CDS YP_001836101.1 182684354 6218495 complement(1371556..1372209) 1 NC_010582.1 phosphate transport system regulatory protein PhoU 1372209 6218495 SPCG_1384 Streptococcus pneumoniae CGSP14 phosphate transport system regulatory protein PhoU YP_001836101.1 1371556 R 516950 CDS YP_001836102.1 182684355 6218472 complement(1372221..1372979) 1 NC_010582.1 ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation; phosphate transporter ATP-binding protein 1372979 6218472 SPCG_1385 Streptococcus pneumoniae CGSP14 phosphate transporter ATP-binding protein YP_001836102.1 1372221 R 516950 CDS YP_001836103.1 182684356 6218478 complement(1372992..1373795) 1 NC_010582.1 ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation; phosphate transporter ATP-binding protein 1373795 6218478 SPCG_1386 Streptococcus pneumoniae CGSP14 phosphate transporter ATP-binding protein YP_001836103.1 1372992 R 516950 CDS YP_001836104.1 182684357 6218477 complement(1373806..1374690) 1 NC_010582.1 phosphate ABC transporter permease 1374690 6218477 SPCG_1387 Streptococcus pneumoniae CGSP14 phosphate ABC transporter permease YP_001836104.1 1373806 R 516950 CDS YP_001836105.1 182684358 6218499 complement(1374680..1375597) 1 NC_010582.1 phosphate ABC transporter permease 1375597 6218499 SPCG_1388 Streptococcus pneumoniae CGSP14 phosphate ABC transporter permease YP_001836105.1 1374680 R 516950 CDS YP_001836106.1 182684359 6218273 complement(1375597..1376475) 1 NC_010582.1 phosphate ABC transporter substrate-binding protein 1376475 6218273 SPCG_1389 Streptococcus pneumoniae CGSP14 phosphate ABC transporter substrate-binding protein YP_001836106.1 1375597 R 516950 CDS YP_001836107.1 182684360 6216434 complement(1377049..1378353) 1 NC_010582.1 NOL1/NOP2/sun family protein 1378353 6216434 SPCG_1390 Streptococcus pneumoniae CGSP14 NOL1/NOP2/sun family protein YP_001836107.1 1377049 R 516950 CDS YP_001836108.1 182684361 6216969 complement(1378354..1379127) 1 NC_010582.1 inositol monophosphatase family protein 1379127 6216969 SPCG_1391 Streptococcus pneumoniae CGSP14 inositol monophosphatase family protein YP_001836108.1 1378354 R 516950 CDS YP_001836109.1 182684362 6216325 complement(1379117..1379395) 1 NC_010582.1 hypothetical protein 1379395 6216325 SPCG_1392 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836109.1 1379117 R 516950 CDS YP_001836110.1 182684363 6218582 complement(1379395..1379796) 1 NC_010582.1 the anti-alpha factor Spx interacts with RNA polymerase alpha subunit C-terminal domain in a region that interacts with the sigma 70 subunit and may interfere with activation of promoters; in Bacillus subtilis this protein is a substrate for ClpXP protease; blocks transcription of the competence regulatory gene encoded by the srf operon; regulates a number of genes involved in thiol homeostasis including trxA and trxB; monomeric member of ArsC family of proteins; does not bind DNA; contains a disulfide bond between C10 and C13 which may sense disulfide stress; transcriptional regulator Spx 1379796 spxA 6218582 spxA Streptococcus pneumoniae CGSP14 transcriptional regulator Spx YP_001836110.1 1379395 R 516950 CDS YP_001836111.1 182684364 6217687 complement(1380006..1380656) 1 NC_010582.1 hypothetical protein 1380656 6217687 SPCG_1394 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836111.1 1380006 R 516950 CDS YP_001836112.1 182684365 6216944 complement(1380613..1381386) 1 NC_010582.1 HAD superfamily hydrolase 1381386 6216944 SPCG_1395 Streptococcus pneumoniae CGSP14 HAD superfamily hydrolase YP_001836112.1 1380613 R 516950 CDS YP_001836113.1 182684366 6218454 complement(1381397..1382134) 1 NC_010582.1 acyl-ACP thioesterase 1382134 6218454 SPCG_1396 Streptococcus pneumoniae CGSP14 acyl-ACP thioesterase YP_001836113.1 1381397 R 516950 CDS YP_001836114.1 182684367 6218458 complement(1382139..1383269) 1 NC_010582.1 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III; coproporphyrinogen III oxidase 1383269 hemN 6218458 hemN Streptococcus pneumoniae CGSP14 coproporphyrinogen III oxidase YP_001836114.1 1382139 R 516950 CDS YP_001836115.1 182684368 6218456 complement(1383353..1383742) 1 NC_010582.1 hypothetical protein 1383742 6218456 SPCG_1398 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836115.1 1383353 R 516950 CDS YP_001836116.1 182684369 6218412 complement(1383758..1384141) 1 NC_010582.1 hypothetical protein 1384141 6218412 SPCG_1399 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836116.1 1383758 R 516950 CDS YP_001836117.1 182684370 6218459 complement(1384142..1384942) 1 NC_010582.1 transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein; prolipoprotein diacylglyceryl transferase 1384942 lgt 6218459 lgt Streptococcus pneumoniae CGSP14 prolipoprotein diacylglyceryl transferase YP_001836117.1 1384142 R 516950 CDS YP_001836118.1 182684371 6218462 complement(1384923..1385873) 1 NC_010582.1 catalyzes the phosphorylation of the phosphocarrier protein HPr of the bacterial phosphotransferase system; HPr kinase/phosphorylase 1385873 hprK 6218462 hprK Streptococcus pneumoniae CGSP14 HPr kinase/phosphorylase YP_001836118.1 1384923 R 516950 CDS YP_001836119.1 182684372 6218100 complement(1385988..1386188) 1 NC_010582.1 a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA; 30S ribosomal protein S21 1386188 rpsU 6218100 rpsU Streptococcus pneumoniae CGSP14 30S ribosomal protein S21 YP_001836119.1 1385988 R 516950 CDS YP_001836120.1 182684373 6218481 complement(1386304..1387026) 1 NC_010582.1 glucosamine-6-phosphate isomerase 1387026 nagB 6218481 nagB Streptococcus pneumoniae CGSP14 glucosamine-6-phosphate isomerase YP_001836120.1 1386304 R 516950 CDS YP_001836121.1 182684374 6217772 1387150..1388190 1 NC_010582.1 Synthesizes oQ from preQ1 in a single S-adenosylmethionine-requiring step; S-adenosylmethionine--tRNA ribosyltransferase-isomerase 1388190 queA 6217772 queA Streptococcus pneumoniae CGSP14 S-adenosylmethionine--tRNA ribosyltransferase-isomerase YP_001836121.1 1387150 D 516950 CDS YP_001836122.1 182684375 6217778 complement(1388851..1389240) 1 NC_010582.1 choline binding protein 1389240 6217778 SPCG_1405 Streptococcus pneumoniae CGSP14 choline binding protein YP_001836122.1 1388851 R 516950 CDS YP_001836123.1 182684376 6218338 complement(1390701..1391252) 1 NC_010582.1 acetyltransferase 1391252 6218338 SPCG_1406 Streptococcus pneumoniae CGSP14 acetyltransferase YP_001836123.1 1390701 R 516950 CDS YP_001836124.1 182684377 6217773 complement(1391602..1392426) 1 NC_010582.1 catalyzes the formation of nicotinamide adenine dinucleotide (NAD) from nicotinic acid adenine dinucleotide (NAAD) using either ammonia or glutamine as the amide donor and ATP; ammonia-utilizing enzymes include the ones from Bacillus and Escherichia coli while glutamine-utilizing enzymes include the Mycobacterial one; forms homodimers; NAD synthetase 1392426 nadE 6217773 nadE Streptococcus pneumoniae CGSP14 NAD synthetase YP_001836124.1 1391602 R 516950 CDS YP_001836125.1 182684378 6218107 complement(1392423..1393883) 1 NC_010582.1 catalyzes the formation of 5-phospho-alpha-D-ribose 1-diphosphate and nicotinate from nicotinate D-ribonucleotide and diphosphate; nicotinate phosphoribosyltransferase 1393883 6218107 SPCG_1408 Streptococcus pneumoniae CGSP14 nicotinate phosphoribosyltransferase YP_001836125.1 1392423 R 516950 CDS YP_001836126.1 182684379 6217776 complement(1393999..1394487) 1 NC_010582.1 hypothetical protein 1394487 6217776 SPCG_1409 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836126.1 1393999 R 516950 CDS YP_001836127.1 182684380 6218514 complement(1395150..1395551) 1 NC_010582.1 hypothetical protein 1395551 6218514 SPCG_1410 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836127.1 1395150 R 516950 CDS YP_001836128.1 182684381 6217559 complement(1395567..1395701) 1 NC_010582.1 hypothetical protein 1395701 6217559 SPCG_1411 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836128.1 1395567 R 516950 CDS YP_001836129.1 182684382 6217314 complement(1395711..1396031) 1 NC_010582.1 hypothetical protein 1396031 6217314 SPCG_1412 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836129.1 1395711 R 516950 CDS YP_001836130.1 182684383 6218426 complement(1396041..1396289) 1 NC_010582.1 hypothetical protein 1396289 6218426 SPCG_1413 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836130.1 1396041 R 516950 CDS YP_001836131.1 182684384 6218419 complement(1396792..1397517) 1 NC_010582.1 U32 family peptidase 1397517 6218419 SPCG_1414 Streptococcus pneumoniae CGSP14 U32 family peptidase YP_001836131.1 1396792 R 516950 CDS YP_001836132.1 182684385 6218418 1397670..1397837 1 NC_010582.1 hypothetical protein 1397837 6218418 SPCG_1415 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836132.1 1397670 D 516950 CDS YP_001836133.1 182684386 6218529 complement(1398092..1399396) 1 NC_010582.1 U32 family peptidase 1399396 6218529 SPCG_1416 Streptococcus pneumoniae CGSP14 U32 family peptidase YP_001836133.1 1398092 R 516950 CDS YP_001836134.1 182684387 6216370 1400002..1400184 1 NC_010582.1 hypothetical protein 1400184 6216370 SPCG_1417 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836134.1 1400002 D 516950 CDS YP_001836135.1 182684388 6217691 1400368..1400556 1 NC_010582.1 hypothetical protein 1400556 6217691 SPCG_1418 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836135.1 1400368 D 516950 CDS YP_001836136.1 182684389 6217482 1400553..1401743 1 NC_010582.1 type II DNA modification methyltransferase 1401743 6217482 SPCG_1419 Streptococcus pneumoniae CGSP14 type II DNA modification methyltransferase YP_001836136.1 1400553 D 516950 CDS YP_001836137.1 182684390 6216562 1401990..1402136 1 NC_010582.1 hypothetical protein 1402136 6216562 SPCG_1420 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836137.1 1401990 D 516950 CDS YP_001836138.1 182684391 6216695 complement(1402258..1403250) 1 NC_010582.1 AraC family transcriptional regulator 1403250 6216695 SPCG_1421 Streptococcus pneumoniae CGSP14 AraC family transcriptional regulator YP_001836138.1 1402258 R 516950 CDS YP_001836139.1 182684392 6216791 1403404..1405164 1 NC_010582.1 ABC transporter ATP-binding protein/permease 1405164 6216791 SPCG_1422 Streptococcus pneumoniae CGSP14 ABC transporter ATP-binding protein/permease YP_001836139.1 1403404 D 516950 CDS YP_001836140.1 182684393 6216994 1405124..1406869 1 NC_010582.1 ABC transporter ATP-binding protein 1406869 6216994 SPCG_1423 Streptococcus pneumoniae CGSP14 ABC transporter ATP-binding protein YP_001836140.1 1405124 D 516950 CDS YP_001836141.1 182684394 6216941 1406880..1407509 1 NC_010582.1 hypothetical protein 1407509 6216941 SPCG_1424 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836141.1 1406880 D 516950 CDS YP_001836142.1 182684395 6216636 1407458..1407967 1 NC_010582.1 hypothetical protein 1407967 6216636 SPCG_1425 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836142.1 1407458 D 516950 CDS YP_001836143.1 182684396 6217068 1407955..1409319 1 NC_010582.1 ABC transporter ATP-binding protein 1409319 6217068 SPCG_1426 Streptococcus pneumoniae CGSP14 ABC transporter ATP-binding protein YP_001836143.1 1407955 D 516950 CDS YP_001836144.1 182684397 6216632 complement(1410250..1410546) 1 NC_010582.1 hypothetical protein 1410546 6216632 SPCG_1427 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836144.1 1410250 R 516950 CDS YP_001836145.1 182684398 6218111 complement(1410619..1410903) 1 NC_010582.1 hypothetical protein 1410903 6218111 SPCG_1428 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836145.1 1410619 R 516950 CDS YP_001836146.1 182684399 6216744 complement(1410950..1411156) 1 NC_010582.1 hypothetical protein 1411156 6216744 SPCG_1429 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836146.1 1410950 R 516950 CDS YP_001836147.1 182684400 6217435 complement(1411320..1411514) 1 NC_010582.1 hypothetical protein 1411514 6217435 SPCG_1430 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836147.1 1411320 R 516950 CDS YP_001836148.1 182684401 6218029 complement(1411833..1412069) 1 NC_010582.1 hypothetical protein 1412069 6218029 SPCG_1431 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836148.1 1411833 R 516950 CDS YP_001836149.1 182684402 6216864 complement(1412050..1412289) 1 NC_010582.1 IS66 family Orf1 1412289 6216864 SPCG_1432 Streptococcus pneumoniae CGSP14 IS66 family Orf1 YP_001836149.1 1412050 R 516950 CDS YP_001836150.1 182684403 6217574 complement(1412539..1414101) 1 NC_010582.1 contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway; GMP synthase 1414101 guaA 6217574 guaA Streptococcus pneumoniae CGSP14 GMP synthase YP_001836150.1 1412539 R 516950 CDS YP_001836151.1 182684404 6216567 1414234..1414941 1 NC_010582.1 GntR family transcriptional regulator 1414941 6216567 SPCG_1434 Streptococcus pneumoniae CGSP14 GntR family transcriptional regulator YP_001836151.1 1414234 D 516950 CDS YP_001836152.1 182684405 6218187 complement(1414984..1415940) 1 NC_010582.1 membrane protein 1415940 6218187 SPCG_1435 Streptococcus pneumoniae CGSP14 membrane protein YP_001836152.1 1414984 R 516950 CDS YP_001836153.1 182684406 6218026 complement(1415889..1416824) 1 NC_010582.1 hypothetical protein 1416824 6218026 SPCG_1436 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836153.1 1415889 R 516950 CDS YP_001836154.1 182684407 6217475 complement(1416821..1417561) 1 NC_010582.1 cppA protein 1417561 cppA 6217475 cppA Streptococcus pneumoniae CGSP14 cppA protein YP_001836154.1 1416821 R 516950 CDS YP_001836155.1 182684408 6218236 complement(1417630..1418265) 1 NC_010582.1 platelet activating factor 1418265 6218236 SPCG_1438 Streptococcus pneumoniae CGSP14 platelet activating factor YP_001836155.1 1417630 R 516950 CDS YP_001836156.1 182684409 6217923 complement(1418267..1419094) 1 NC_010582.1 cof family protein 1419094 6217923 SPCG_1439 Streptococcus pneumoniae CGSP14 cof family protein YP_001836156.1 1418267 R 516950 CDS YP_001836157.1 182684410 6217368 complement(1419116..1419451) 1 NC_010582.1 hypothetical protein 1419451 6217368 SPCG_1440 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836157.1 1419116 R 516950 CDS YP_001836158.1 182684411 6217499 complement(1419452..1419964) 1 NC_010582.1 hypothetical protein 1419964 6217499 SPCG_1441 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836158.1 1419452 R 516950 CDS YP_001836159.1 182684412 6217907 complement(1420058..1420180) 1 NC_010582.1 hypothetical protein 1420180 6217907 SPCG_1442 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836159.1 1420058 R 516950 CDS YP_001836160.1 182684413 6217864 1420692..1421303 1 NC_010582.1 cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+); peptide deformylase 1421303 def 6217864 def Streptococcus pneumoniae CGSP14 peptide deformylase YP_001836160.1 1420692 D 516950 CDS YP_001836161.1 182684414 6218013 1421315..1422076 1 NC_010582.1 spoU rRNA methylase family protein 1422076 trmH 6218013 trmH Streptococcus pneumoniae CGSP14 spoU rRNA methylase family protein YP_001836161.1 1421315 D 516950 CDS YP_001836162.1 182684415 6218129 complement(1422115..1423026) 1 NC_010582.1 thioredoxin reductase 1423026 trxB 6218129 trxB Streptococcus pneumoniae CGSP14 thioredoxin reductase YP_001836162.1 1422115 R 516950 CDS YP_001836163.1 182684416 6217386 complement(1423092..1423328) 1 NC_010582.1 hypothetical protein 1423328 6217386 SPCG_1446 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836163.1 1423092 R 516950 CDS YP_001836164.1 182684417 6217769 complement(1423394..1424137) 1 NC_010582.1 amino acid ABC transporter ATP-binding protein 1424137 6217769 SPCG_1447 Streptococcus pneumoniae CGSP14 amino acid ABC transporter ATP-binding protein YP_001836164.1 1423394 R 516950 CDS YP_001836165.1 182684418 6217480 complement(1424137..1424937) 1 NC_010582.1 amino acid ABC transporter permease 1424937 6217480 SPCG_1448 Streptococcus pneumoniae CGSP14 amino acid ABC transporter permease YP_001836165.1 1424137 R 516950 CDS YP_001836166.1 182684419 6218105 complement(1425095..1425451) 1 NC_010582.1 hypothetical protein 1425451 6218105 SPCG_1449 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836166.1 1425095 R 516950 CDS YP_001836167.1 182684420 6218482 complement(1425464..1425976) 1 NC_010582.1 methylated-DNA--protein-cysteine S-methyltransferase 1425976 ogt 6218482 ogt Streptococcus pneumoniae CGSP14 methylated-DNA--protein-cysteine S-methyltransferase YP_001836167.1 1425464 R 516950 CDS YP_001836168.1 182684421 6217963 complement(1425976..1426470) 1 NC_010582.1 acetyltransferase 1426470 6217963 SPCG_1451 Streptococcus pneumoniae CGSP14 acetyltransferase YP_001836168.1 1425976 R 516950 CDS YP_001836169.1 182684422 6216532 1426599..1427051 1 NC_010582.1 hypothetical protein 1427051 6216532 SPCG_1452 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836169.1 1426599 D 516950 CDS YP_001836170.1 182684423 6217118 1427048..1427695 1 NC_010582.1 hemolysin 1427695 6217118 SPCG_1453 Streptococcus pneumoniae CGSP14 hemolysin YP_001836170.1 1427048 D 516950 CDS YP_001836171.1 182684424 6218202 complement(1428047..1429363) 1 NC_010582.1 hypothetical protein 1429363 6218202 SPCG_1454 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836171.1 1428047 R 516950 CDS YP_001836172.1 182684425 6217558 complement(1429381..1430181) 1 NC_010582.1 ABC transporter ATP-binding protein 1430181 6217558 SPCG_1455 Streptococcus pneumoniae CGSP14 ABC transporter ATP-binding protein YP_001836172.1 1429381 R 516950 CDS YP_001836173.1 182684426 6217449 complement(1430669..1431253) 1 NC_010582.1 with PdxST is involved in the biosynthesis of pyridoxal 5'-phosphate; PdxT catalyzes the hydrolysis of glutamine to glutamate and ammonia; PdxS utilizes the ammonia to synthesize pyridoxal 5'-phosphate; glutamine amidotransferase subunit PdxT 1431253 6217449 SPCG_1456 Streptococcus pneumoniae CGSP14 glutamine amidotransferase subunit PdxT YP_001836173.1 1430669 R 516950 CDS YP_001836174.1 182684427 6218295 complement(1431254..1432147) 1 NC_010582.1 with PdxT forms pyridoxal 5'-phosphate from glutamine, either ribose 5-phosphate or ribulose 5-phosphate, and either glyceraldehyde 3-phosphate or dihydroxyacetone phosphate; pyridoxal biosynthesis lyase PdxS 1432147 pdx1 6218295 pdx1 Streptococcus pneumoniae CGSP14 pyridoxal biosynthesis lyase PdxS YP_001836174.1 1431254 R 516950 CDS YP_001836175.1 182684428 6216649 complement(1432281..1433660) 1 NC_010582.1 NADH oxidase 1433660 nox 6216649 nox Streptococcus pneumoniae CGSP14 NADH oxidase YP_001836175.1 1432281 R 516950 CDS YP_001836176.1 182684429 6216455 1433954..1434877 1 NC_010582.1 thiamine biosynthesis protein ApbE 1434877 apbE 6216455 apbE Streptococcus pneumoniae CGSP14 thiamine biosynthesis protein ApbE YP_001836176.1 1433954 D 516950 CDS YP_001836177.1 182684430 6218061 1434937..1435542 1 NC_010582.1 oxidoreductase 1435542 6218061 SPCG_1460 Streptococcus pneumoniae CGSP14 oxidoreductase YP_001836177.1 1434937 D 516950 CDS YP_001836178.1 182684431 6217628 1435561..1436805 1 NC_010582.1 oxidoreductase 1436805 6217628 SPCG_1461 Streptococcus pneumoniae CGSP14 oxidoreductase YP_001836178.1 1435561 D 516950 CDS YP_001836179.1 182684432 6217852 complement(1437028..1437285) 1 NC_010582.1 hypothetical protein 1437285 6217852 SPCG_1462 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836179.1 1437028 R 516950 CDS YP_001836180.1 182684433 6217052 complement(1437327..1439363) 1 NC_010582.1 glycine--tRNA ligase beta chain; glyS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; glycyl-tRNA synthetase subunit beta 1439363 glyS 6217052 glyS Streptococcus pneumoniae CGSP14 glycyl-tRNA synthetase subunit beta YP_001836180.1 1437327 R 516950 CDS YP_001836181.1 182684434 6217272 complement(1439649..1440566) 1 NC_010582.1 glycine--tRNA ligase alpha chain; GlyRS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; glycyl-tRNA synthetase subunit alpha 1440566 glyQ 6217272 glyQ Streptococcus pneumoniae CGSP14 glycyl-tRNA synthetase subunit alpha YP_001836181.1 1439649 R 516950 CDS YP_001836182.1 182684435 6217275 complement(1440758..1441537) 1 NC_010582.1 hypothetical protein 1441537 6217275 SPCG_1465 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836182.1 1440758 R 516950 CDS YP_001836183.1 182684436 6217751 complement(1441792..1442634) 1 NC_010582.1 aldo/keto reductase family oxidoreductase 1442634 6217751 SPCG_1466 Streptococcus pneumoniae CGSP14 aldo/keto reductase family oxidoreductase YP_001836183.1 1441792 R 516950 CDS YP_001836184.1 182684437 6217943 complement(1442748..1444190) 1 NC_010582.1 peptidoglycan N-acetylglucosamine deacetylase A 1444190 pgdA 6217943 pgdA Streptococcus pneumoniae CGSP14 peptidoglycan N-acetylglucosamine deacetylase A YP_001836184.1 1442748 R 516950 CDS YP_001836185.1 182684438 6216787 complement(1444374..1444751) 1 NC_010582.1 hypothetical protein 1444751 6216787 SPCG_1468 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836185.1 1444374 R 516950 CDS YP_001836186.1 182684439 6217583 1444771..1445853 1 NC_010582.1 Gfo/Idh/MocA family oxidoreductase 1445853 mocA 6217583 mocA Streptococcus pneumoniae CGSP14 Gfo/Idh/MocA family oxidoreductase YP_001836186.1 1444771 D 516950 CDS YP_001836187.1 182684440 6217939 1445850..1446932 1 NC_010582.1 DEAD/DEAH box helicase 1446932 6217939 SPCG_1470 Streptococcus pneumoniae CGSP14 DEAD/DEAH box helicase YP_001836187.1 1445850 D 516950 CDS YP_001836188.1 182684441 6217312 complement(1446996..1447262) 1 NC_010582.1 hypothetical protein 1447262 6217312 SPCG_1471 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836188.1 1446996 R 516950 CDS YP_001836189.1 182684442 6217660 complement(1447527..1447634) 1 NC_010582.1 hypothetical protein 1447634 6217660 SPCG_1472 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836189.1 1447527 R 516950 CDS YP_001836190.1 182684443 6217564 complement(1447886..1448017) 1 NC_010582.1 hypothetical protein 1448017 6217564 SPCG_1473 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836190.1 1447886 R 516950 CDS YP_001836191.1 182684444 6217654 complement(1448401..1449615) 1 NC_010582.1 EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu; elongation factor Tu 1449615 tuf 6217654 tuf Streptococcus pneumoniae CGSP14 elongation factor Tu YP_001836191.1 1448401 R 516950 CDS YP_001836192.1 182684445 6218257 complement(1450530..1451399) 1 NC_010582.1 glycerol uptake facilitator protein 1451399 glpF 6218257 glpF Streptococcus pneumoniae CGSP14 glycerol uptake facilitator protein YP_001836192.1 1450530 R 516950 CDS YP_001836193.1 182684446 6217674 complement(1451622..1451783) 1 NC_010582.1 cell wall surface anchor family protein 1451783 6217674 SPCG_1476 Streptococcus pneumoniae CGSP14 cell wall surface anchor family protein YP_001836193.1 1451622 R 516950 CDS YP_001836194.1 182684447 6216656 complement(1452100..1453212) 1 NC_010582.1 hypothetical protein 1453212 6216656 SPCG_1477 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836194.1 1452100 R 516950 CDS YP_001836195.1 182684448 6217739 complement(1453850..1453945) 1 NC_010582.1 hypothetical protein 1453945 6217739 SPCG_1478 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836195.1 1453850 R 516950 CDS YP_001836196.1 182684449 6217025 complement(1453911..1454210) 1 NC_010582.1 transposase, IS630-Spn1 related, Orf2 1454210 6217025 SPCG_1479 Streptococcus pneumoniae CGSP14 transposase, IS630-Spn1 related, Orf2 YP_001836196.1 1453911 R 516950 CDS YP_001836197.1 182684450 6217502 complement(1454430..1454645) 1 NC_010582.1 hypothetical protein 1454645 6217502 SPCG_1480 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836197.1 1454430 R 516950 CDS YP_001836198.1 182684451 6217664 1454989..1456707 1 NC_010582.1 phosphoglucomutase 1456707 pgm 6217664 pgm Streptococcus pneumoniae CGSP14 phosphoglucomutase YP_001836198.1 1454989 D 516950 CDS YP_001836199.1 182684452 6217243 complement(1456757..1457284) 1 NC_010582.1 degenerate transposase 1457284 6217243 SPCG_1482 Streptococcus pneumoniae CGSP14 degenerate transposase YP_001836199.1 1456757 R 516950 CDS YP_001836200.1 182684453 6216450 complement(1457565..1458083) 1 NC_010582.1 degenerate transposase 1458083 6216450 SPCG_1483 Streptococcus pneumoniae CGSP14 degenerate transposase YP_001836200.1 1457565 R 516950 CDS YP_001836201.1 182684454 6216407 1458310..1458657 1 NC_010582.1 bacterocin transport accessory protein 1458657 bta 6216407 bta Streptococcus pneumoniae CGSP14 bacterocin transport accessory protein YP_001836201.1 1458310 D 516950 CDS YP_001836202.1 182684455 6217613 complement(1458937..1459773) 1 NC_010582.1 amino acid ABC transporter amino acid-binding protein 1459773 6217613 SPCG_1485 Streptococcus pneumoniae CGSP14 amino acid ABC transporter amino acid-binding protein YP_001836202.1 1458937 R 516950 CDS YP_001836203.1 182684456 6218010 complement(1459786..1460415) 1 NC_010582.1 amino acid ABC transporter ATP-binding protein 1460415 6218010 SPCG_1486 Streptococcus pneumoniae CGSP14 amino acid ABC transporter ATP-binding protein YP_001836203.1 1459786 R 516950 CDS YP_001836204.1 182684457 6216685 complement(1460425..1461123) 1 NC_010582.1 amino acid ABC transporter permease 1461123 6216685 SPCG_1487 Streptococcus pneumoniae CGSP14 amino acid ABC transporter permease YP_001836204.1 1460425 R 516950 CDS YP_001836205.1 182684458 6217031 complement(1461212..1462456) 1 NC_010582.1 hypothetical protein 1462456 6217031 SPCG_1488 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836205.1 1461212 R 516950 CDS YP_001836206.1 182684459 6217240 complement(1462431..1463597) 1 NC_010582.1 membrane protein 1463597 6217240 SPCG_1489 Streptococcus pneumoniae CGSP14 membrane protein YP_001836206.1 1462431 R 516950 CDS YP_001836207.1 182684460 6216408 1463741..1464754 1 NC_010582.1 hypothetical protein 1464754 6216408 SPCG_1490 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836207.1 1463741 D 516950 CDS YP_001836208.1 182684461 6218386 complement(1464799..1465218) 1 NC_010582.1 part of catalytic core of ATP synthase; alpha(3)beta(3)gamma(1)delta(1)epsilon(1); involved in producing ATP from ADP in the presence of the proton motive force across the membrane; F0F1 ATP synthase subunit epsilon 1465218 atpC 6218386 atpC Streptococcus pneumoniae CGSP14 F0F1 ATP synthase subunit epsilon YP_001836208.1 1464799 R 516950 CDS YP_001836209.1 182684462 6217054 complement(1465229..1466635) 1 NC_010582.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit; F0F1 ATP synthase subunit beta 1466635 atpD 6217054 atpD Streptococcus pneumoniae CGSP14 F0F1 ATP synthase subunit beta YP_001836209.1 1465229 R 516950 CDS YP_001836210.1 182684463 6216822 complement(1466721..1467599) 1 NC_010582.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is a regulatory subunit; F0F1 ATP synthase subunit gamma 1467599 atpG 6216822 atpG Streptococcus pneumoniae CGSP14 F0F1 ATP synthase subunit gamma YP_001836210.1 1466721 R 516950 CDS YP_001836211.1 182684464 6217652 complement(1467615..1469120) 1 NC_010582.1 produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit; F0F1 ATP synthase subunit alpha 1469120 atpA 6217652 atpA Streptococcus pneumoniae CGSP14 F0F1 ATP synthase subunit alpha YP_001836211.1 1467615 R 516950 CDS YP_001836212.1 182684465 6218076 complement(1469135..1469671) 1 NC_010582.1 Produces ATP from ADP in the presence of a proton gradient across the membrane; the delta subunit is part of the catalytic core of the ATP synthase complex; F0F1 ATP synthase subunit delta 1469671 atpH 6218076 atpH Streptococcus pneumoniae CGSP14 F0F1 ATP synthase subunit delta YP_001836212.1 1469135 R 516950 CDS YP_001836213.1 182684466 6218281 complement(1469671..1470165) 1 NC_010582.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit B is part of the membrane proton channel.; F0F1 ATP synthase subunit B 1470165 atpF 6218281 atpF Streptococcus pneumoniae CGSP14 F0F1 ATP synthase subunit B YP_001836213.1 1469671 R 516950 CDS YP_001836214.1 182684467 6217961 complement(1470179..1470895) 1 NC_010582.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0; F0F1 ATP synthase subunit A 1470895 atpB 6217961 atpB Streptococcus pneumoniae CGSP14 F0F1 ATP synthase subunit A YP_001836214.1 1470179 R 516950 CDS YP_001836215.1 182684468 6216578 complement(1470930..1471130) 1 NC_010582.1 produces ATP from ADP in the presence of a proton gradient across the membrane; subunit C is part of the membrane proton channel F0; F0F1 ATP synthase subunit C 1471130 atpE 6216578 atpE Streptococcus pneumoniae CGSP14 F0F1 ATP synthase subunit C YP_001836215.1 1470930 R 516950 CDS YP_001836216.1 182684469 6218017 complement(1471205..1472257) 1 NC_010582.1 IS1239 transposase 1472257 6218017 SPCG_1499 Streptococcus pneumoniae CGSP14 IS1239 transposase YP_001836216.1 1471205 R 516950 CDS YP_001836217.1 182684470 6217236 complement(1472670..1473152) 1 NC_010582.1 acetyltransferase 1473152 6217236 SPCG_1500 Streptococcus pneumoniae CGSP14 acetyltransferase YP_001836217.1 1472670 R 516950 CDS YP_001836218.1 182684471 6217523 complement(1473186..1473728) 1 NC_010582.1 hypothetical protein 1473728 6217523 SPCG_1501 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836218.1 1473186 R 516950 CDS YP_001836219.1 182684472 6218054 complement(1473756..1474247) 1 NC_010582.1 necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus; transcription elongation factor GreA 1474247 greA 6218054 greA Streptococcus pneumoniae CGSP14 transcription elongation factor GreA YP_001836219.1 1473756 R 516950 CDS YP_001836220.1 182684473 6217965 complement(1474309..1475964) 1 NC_010582.1 hypothetical protein 1475964 6217965 SPCG_1503 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836220.1 1474309 R 516950 CDS YP_001836221.1 182684474 6216525 complement(1476045..1476539) 1 NC_010582.1 acetyltransferase 1476539 6216525 SPCG_1504 Streptococcus pneumoniae CGSP14 acetyltransferase YP_001836221.1 1476045 R 516950 CDS YP_001836222.1 182684475 6217997 complement(1476536..1477000) 1 NC_010582.1 acetyltransferase 1477000 6217997 SPCG_1505 Streptococcus pneumoniae CGSP14 acetyltransferase YP_001836222.1 1476536 R 516950 CDS YP_001836223.1 182684476 6217329 complement(1477010..1478344) 1 NC_010582.1 Catalyzes the formation of UDP-N-acetylmuramoyl-L-alanine from UDP-N-acetylmuramate and L-alanine in peptidoglycan synthesis; UDP-N-acetylmuramate--L-alanine ligase 1478344 murC 6217329 murC Streptococcus pneumoniae CGSP14 UDP-N-acetylmuramate--L-alanine ligase YP_001836223.1 1477010 R 516950 CDS YP_001836224.1 182684477 6218075 complement(1478355..1478972) 1 NC_010582.1 hypothetical protein 1478972 6218075 SPCG_1507 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836224.1 1478355 R 516950 CDS YP_001836225.1 182684478 6217996 complement(1479020..1482118) 1 NC_010582.1 snf2 family protein 1482118 snf 6217996 snf Streptococcus pneumoniae CGSP14 snf2 family protein YP_001836225.1 1479020 R 516950 CDS YP_001836226.1 182684479 6217707 complement(1482211..1483377) 1 NC_010582.1 class II aminotransferase 1483377 patB 6217707 patB Streptococcus pneumoniae CGSP14 class II aminotransferase YP_001836226.1 1482211 R 516950 CDS YP_001836227.1 182684480 6217578 complement(1483385..1484479) 1 NC_010582.1 catalyzes the formation of cystathionine from L-cysteine and O-succinyl-L-homoserine; cystathionine gamma-synthase 1484479 metB 6217578 metB Streptococcus pneumoniae CGSP14 cystathionine gamma-synthase YP_001836227.1 1483385 R 516950 CDS YP_001836228.1 182684481 6217569 complement(1484636..1485229) 1 NC_010582.1 hypothetical protein 1485229 6217569 SPCG_1511 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836228.1 1484636 R 516950 CDS YP_001836229.1 182684482 6217461 complement(1485217..1485756) 1 NC_010582.1 hypothetical protein 1485756 6217461 SPCG_1512 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836229.1 1485217 R 516950 CDS YP_001836230.1 182684483 6218150 complement(1485765..1486310) 1 NC_010582.1 multidrug ABC transporter ATPase/permease 1486310 6218150 SPCG_1513 Streptococcus pneumoniae CGSP14 multidrug ABC transporter ATPase/permease YP_001836230.1 1485765 R 516950 CDS YP_001836231.1 182684484 6217989 complement(1486482..1488440) 1 NC_010582.1 oligopeptide ABC transporter oligopeptide-binding protein AliB 1488440 aliB 6217989 aliB Streptococcus pneumoniae CGSP14 oligopeptide ABC transporter oligopeptide-binding protein AliB YP_001836231.1 1486482 R 516950 CDS YP_001836232.1 182684485 6217733 complement(1488427..1488522) 1 NC_010582.1 hypothetical protein 1488522 6217733 SPCG_1515 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836232.1 1488427 R 516950 CDS YP_001836233.1 182684486 6216698 complement(1488643..1490280) 1 NC_010582.1 polysaccharide biosynthesis protein 1490280 6216698 SPCG_1516 Streptococcus pneumoniae CGSP14 polysaccharide biosynthesis protein YP_001836233.1 1488643 R 516950 CDS YP_001836234.1 182684487 6218057 1490371..1491816 1 NC_010582.1 involved in cell wall formation; peptidoglycan synthesis; cytoplasmic enzyme; catalyzes the addition of lysine to UDP-N-acetylmuramoyl-L-alanyl-D-glutamate forming UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysine; UDP-N-acetylmuramoylalanyl-D-glutamate--L-lysine ligase 1491816 murE 6218057 murE Streptococcus pneumoniae CGSP14 UDP-N-acetylmuramoylalanyl-D-glutamate--L-lysine ligase YP_001836234.1 1490371 D 516950 CDS YP_001836235.1 182684488 6217964 complement(1492110..1492682) 1 NC_010582.1 hypothetical protein 1492682 6217964 SPCG_1518 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836235.1 1492110 R 516950 CDS YP_001836236.1 182684489 6218560 complement(1492719..1493231) 1 NC_010582.1 hypothetical protein 1493231 6218560 SPCG_1519 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836236.1 1492719 R 516950 CDS YP_001836237.1 182684490 6216754 complement(1493318..1494253) 1 NC_010582.1 catalyzes the hydrolysis of pyrophosphate to phosphate; manganese-dependent inorganic pyrophosphatase 1494253 ppaC 6216754 ppaC Streptococcus pneumoniae CGSP14 manganese-dependent inorganic pyrophosphatase YP_001836237.1 1493318 R 516950 CDS YP_001836238.1 182684491 6216395 complement(1494324..1494623) 1 NC_010582.1 hypothetical protein 1494623 6216395 SPCG_1521 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836238.1 1494324 R 516950 CDS YP_001836239.1 182684492 6216357 complement(1494613..1495362) 1 NC_010582.1 hypothetical protein 1495362 6216357 SPCG_1522 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836239.1 1494613 R 516950 CDS YP_001836240.1 182684493 6216337 complement(1495416..1495802) 1 NC_010582.1 hypothetical protein 1495802 6216337 SPCG_1523 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836240.1 1495416 R 516950 CDS YP_001836241.1 182684494 6216365 complement(1495777..1497177) 1 NC_010582.1 cof family protein/peptidyl-prolyl cis-trans isomerase, cyclophilin type 1497177 6216365 SPCG_1524 Streptococcus pneumoniae CGSP14 cof family protein/peptidyl-prolyl cis-trans isomerase, cyclophilin type YP_001836241.1 1495777 R 516950 CDS YP_001836242.1 182684495 6217972 complement(1497472..1497711) 1 NC_010582.1 binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit; 30S ribosomal protein S18 1497711 rpsR 6217972 rpsR Streptococcus pneumoniae CGSP14 30S ribosomal protein S18 YP_001836242.1 1497472 R 516950 CDS YP_001836243.1 182684496 6217063 complement(1497743..1498213) 1 NC_010582.1 binds to single stranded DNA and may facilitate the binding and interaction of other proteins to DNA; single-stranded DNA-binding protein 1498213 ssbA 6217063 ssbA Streptococcus pneumoniae CGSP14 single-stranded DNA-binding protein YP_001836243.1 1497743 R 516950 CDS YP_001836244.1 182684497 6218414 complement(1498225..1498515) 1 NC_010582.1 binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21; 30S ribosomal protein S6 1498515 rpsF 6218414 rpsF Streptococcus pneumoniae CGSP14 30S ribosomal protein S6 YP_001836244.1 1498225 R 516950 CDS YP_001836245.1 182684498 6218391 complement(1498669..1500012) 1 NC_010582.1 catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; asparaginyl-tRNA synthetase 1500012 asnC 6218391 asnC Streptococcus pneumoniae CGSP14 asparaginyl-tRNA synthetase YP_001836245.1 1498669 R 516950 CDS YP_001836246.1 182684499 6218476 complement(1500031..1500402) 1 NC_010582.1 hypothetical protein 1500402 6218476 SPCG_1529 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836246.1 1500031 R 516950 CDS YP_001836247.1 182684500 6218489 complement(1500389..1501576) 1 NC_010582.1 catalyzes the formation of oxalozcetate and L-glutamate from L-aspartate and 2-oxoglutarate; aspartate aminotransferase 1501576 aspB 6218489 aspB Streptococcus pneumoniae CGSP14 aspartate aminotransferase YP_001836247.1 1500389 R 516950 CDS YP_001836248.1 182684501 6218568 complement(1501573..1502061) 1 NC_010582.1 hypothetical protein 1502061 6218568 SPCG_1531 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836248.1 1501573 R 516950 CDS YP_001836249.1 182684502 6216955 1502301..1502930 1 NC_010582.1 hypothetical protein 1502930 6216955 SPCG_1532 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836249.1 1502301 D 516950 CDS YP_001836250.1 182684503 6218522 complement(1503208..1503936) 1 NC_010582.1 hypothetical protein 1503936 6218522 SPCG_1533 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836250.1 1503208 R 516950 CDS YP_001836251.1 182684504 6218460 complement(1504030..1504194) 1 NC_010582.1 hypothetical protein 1504194 6218460 SPCG_1534 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836251.1 1504030 R 516950 CDS YP_001836252.1 182684505 6218433 complement(1504347..1505942) 1 NC_010582.1 hypothetical protein 1505942 6218433 SPCG_1535 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836252.1 1504347 R 516950 CDS YP_001836253.1 182684506 6218503 complement(1505954..1506364) 1 NC_010582.1 cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+); peptide deformylase 1506364 def 6218503 def Streptococcus pneumoniae CGSP14 peptide deformylase YP_001836253.1 1505954 R 516950 CDS YP_001836254.1 182684507 6218521 complement(1506480..1507271) 1 NC_010582.1 YghU; B2989; one of eight glutathione transferase proteins from E. coli; glutathione S-transferase 1507271 6218521 SPCG_1537 Streptococcus pneumoniae CGSP14 glutathione S-transferase YP_001836254.1 1506480 R 516950 CDS YP_001836255.1 182684508 6216345 complement(1507284..1510028) 1 NC_010582.1 cation transporter E1-E2 family ATPase 1510028 pacL 6216345 pacL Streptococcus pneumoniae CGSP14 cation transporter E1-E2 family ATPase YP_001836255.1 1507284 R 516950 CDS YP_001836256.1 182684509 6216343 1510284..1511468 1 NC_010582.1 cation efflux family protein 1511468 6216343 SPCG_1539 Streptococcus pneumoniae CGSP14 cation efflux family protein YP_001836256.1 1510284 D 516950 CDS YP_001836257.1 182684510 6217521 complement(1511611..1513482) 1 NC_010582.1 ABC transporter ATP-binding protein 1513482 6217521 SPCG_1540 Streptococcus pneumoniae CGSP14 ABC transporter ATP-binding protein YP_001836257.1 1511611 R 516950 CDS YP_001836258.1 182684511 6217438 complement(1513479..1514678) 1 NC_010582.1 catalyzes the addition and repair of the 3'-terminal CCA sequence in tRNA; these proteins belong to the CCA-adding enzyme subfamily 2 which does not have phosphohydrolase activity; tRNA CCA-pyrophosphorylase 1514678 6217438 SPCG_1541 Streptococcus pneumoniae CGSP14 tRNA CCA-pyrophosphorylase YP_001836258.1 1513479 R 516950 CDS YP_001836259.1 182684512 6216436 complement(1514675..1515442) 1 NC_010582.1 catalyzes the reduction of 2,3-dihydrodipicolinate to 2,3,4,5-tetrahydrodipicolinate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate reductase 1515442 dapB 6216436 dapB Streptococcus pneumoniae CGSP14 dihydrodipicolinate reductase YP_001836259.1 1514675 R 516950 CDS YP_001836260.1 182684513 6217710 complement(1515708..1516556) 1 NC_010582.1 degV family protein 1516556 6217710 SPCG_1543 Streptococcus pneumoniae CGSP14 degV family protein YP_001836260.1 1515708 R 516950 CDS YP_001836261.1 182684514 6217441 complement(1516558..1516944) 1 NC_010582.1 hypothetical protein 1516944 6217441 SPCG_1544 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836261.1 1516558 R 516950 CDS YP_001836262.1 182684515 6216950 complement(1517006..1518358) 1 NC_010582.1 catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; phosphoglucosamine mutase 1518358 glmM 6216950 glmM Streptococcus pneumoniae CGSP14 phosphoglucosamine mutase YP_001836262.1 1517006 R 516950 CDS YP_001836263.1 182684516 6216706 complement(1518382..1519161) 1 NC_010582.1 hypothetical protein 1519161 6216706 SPCG_1546 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836263.1 1518382 R 516950 CDS YP_001836264.1 182684517 6218000 complement(1519148..1520026) 1 NC_010582.1 hypothetical protein 1520026 6218000 SPCG_1547 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836264.1 1519148 R 516950 CDS YP_001836265.1 182684518 6217217 1520141..1521106 1 NC_010582.1 pyridine nucleotide-disulfide oxidoreductase family protein 1521106 6217217 SPCG_1548 Streptococcus pneumoniae CGSP14 pyridine nucleotide-disulfide oxidoreductase family protein YP_001836265.1 1520141 D 516950 CDS YP_001836266.1 182684519 6217597 complement(1521140..1522051) 1 NC_010582.1 hypothetical protein 1522051 6217597 SPCG_1549 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836266.1 1521140 R 516950 CDS YP_001836267.1 182684520 6217120 complement(1522048..1523025) 1 NC_010582.1 hypothetical protein 1523025 6217120 SPCG_1550 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836267.1 1522048 R 516950 CDS YP_001836268.1 182684521 6217571 complement(1523022..1523912) 1 NC_010582.1 hypothetical protein 1523912 6217571 SPCG_1551 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836268.1 1523022 R 516950 CDS YP_001836269.1 182684522 6218487 complement(1523964..1524344) 1 NC_010582.1 endoribonuclease L-PSP 1524344 6218487 SPCG_1552 Streptococcus pneumoniae CGSP14 endoribonuclease L-PSP YP_001836269.1 1523964 R 516950 CDS YP_001836270.1 182684523 6217936 complement(1524355..1524948) 1 NC_010582.1 binds guanine nucleotides; in Escherichia coli depletion results in defective cell division and filamentation; in Bacillus subtilis this gene is essential; ribosome biogenesis GTP-binding protein YsxC 1524948 engB 6217936 engB Streptococcus pneumoniae CGSP14 ribosome biogenesis GTP-binding protein YsxC YP_001836270.1 1524355 R 516950 CDS YP_001836271.1 182684524 6217969 complement(1524951..1526183) 1 NC_010582.1 binds and unfolds substrates as part of the ClpXP protease; ATP-dependent protease ATP-binding subunit ClpX 1526183 clpX 6217969 clpX Streptococcus pneumoniae CGSP14 ATP-dependent protease ATP-binding subunit ClpX YP_001836271.1 1524951 R 516950 CDS YP_001836272.1 182684525 6217889 complement(1526215..1526385) 1 NC_010582.1 hypothetical protein 1526385 6217889 SPCG_1555 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836272.1 1526215 R 516950 CDS YP_001836273.1 182684526 6216793 complement(1526385..1526891) 1 NC_010582.1 dihydrofolate reductase 1526891 dfr 6216793 dfr Streptococcus pneumoniae CGSP14 dihydrofolate reductase YP_001836273.1 1526385 R 516950 CDS YP_001836274.1 182684527 6216748 complement(1527021..1527539) 1 NC_010582.1 non-heme iron-containing ferritin 1527539 6216748 SPCG_1557 Streptococcus pneumoniae CGSP14 non-heme iron-containing ferritin YP_001836274.1 1527021 R 516950 CDS YP_001836275.1 182684528 6216665 1527752..1527844 1 NC_010582.1 hypothetical protein 1527844 6216665 SPCG_1558 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836275.1 1527752 D 516950 CDS YP_001836276.1 182684529 6216707 complement(1528037..1529542) 1 NC_010582.1 lysozyme 1529542 lytC 6216707 lytC Streptococcus pneumoniae CGSP14 lysozyme YP_001836276.1 1528037 R 516950 CDS YP_001836277.1 182684530 6217520 complement(1529580..1530359) 1 NC_010582.1 Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate; triosephosphate isomerase 1530359 tpiA 6217520 tpiA Streptococcus pneumoniae CGSP14 triosephosphate isomerase YP_001836277.1 1529580 R 516950 CDS YP_001836278.1 182684531 6217264 complement(1530436..1531113) 1 NC_010582.1 hypothetical protein 1531113 6217264 SPCG_1561 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836278.1 1530436 R 516950 CDS YP_001836279.1 182684532 6216423 complement(1531122..1532066) 1 NC_010582.1 catalyzes the formation of O-succinyl-L-homoserine from succinyl-CoA and L-homoserine in methionine biosynthesis; homoserine O-succinyltransferase 1532066 metA 6216423 metA Streptococcus pneumoniae CGSP14 homoserine O-succinyltransferase YP_001836279.1 1531122 R 516950 CDS YP_001836280.1 182684533 6217570 complement(1532248..1532778) 1 NC_010582.1 catalyzes a salvage reaction resulting in the formation of AMP which is metabolically less costly than a de novo synthesis; adenine phosphoribosyltransferase 1532778 apt 6217570 apt Streptococcus pneumoniae CGSP14 adenine phosphoribosyltransferase YP_001836280.1 1532248 R 516950 CDS YP_001836281.1 182684534 6218497 complement(1532848..1533606) 1 NC_010582.1 methyltransferase 1533606 6218497 SPCG_1564 Streptococcus pneumoniae CGSP14 methyltransferase YP_001836281.1 1532848 R 516950 CDS YP_001836282.1 182684535 6218593 complement(1534107..1535237) 1 NC_010582.1 sugar ABC transporter ATP-binding protein 1535237 6218593 SPCG_1565 Streptococcus pneumoniae CGSP14 sugar ABC transporter ATP-binding protein YP_001836282.1 1534107 R 516950 CDS YP_001836283.1 182684536 6216363 complement(1535687..1536262) 1 NC_010582.1 isochorismatase family protein 1536262 entB 6216363 entB Streptococcus pneumoniae CGSP14 isochorismatase family protein YP_001836283.1 1535687 R 516950 CDS YP_001836284.1 182684537 6218441 complement(1536262..1537050) 1 NC_010582.1 CodY; DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase (By similarity). It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor; transcriptional repressor CodY 1537050 codY 6218441 codY Streptococcus pneumoniae CGSP14 transcriptional repressor CodY YP_001836284.1 1536262 R 516950 CDS YP_001836285.1 182684538 6216369 complement(1537315..1538889) 1 NC_010582.1 ATP-dependent RNA helicase 1538889 6216369 SPCG_1568 Streptococcus pneumoniae CGSP14 ATP-dependent RNA helicase YP_001836285.1 1537315 R 516950 CDS YP_001836286.1 182684539 6217374 complement(1539088..1540314) 1 NC_010582.1 oxalate:formate antiporter 1540314 oxlT 6217374 oxlT Streptococcus pneumoniae CGSP14 oxalate:formate antiporter YP_001836286.1 1539088 R 516950 CDS YP_001836287.1 182684540 6217834 1540507..1541823 1 NC_010582.1 Involved in disulfide oxidoreductase activity and electron transport; pyridine nucleotide-disulfide oxidoreductase 1541823 merA 6217834 merA Streptococcus pneumoniae CGSP14 pyridine nucleotide-disulfide oxidoreductase YP_001836287.1 1540507 D 516950 CDS YP_001836288.1 182684541 6218022 1541922..1543265 1 NC_010582.1 mur ligase family protein 1543265 6218022 SPCG_1571 Streptococcus pneumoniae CGSP14 mur ligase family protein YP_001836288.1 1541922 D 516950 CDS YP_001836289.1 182684542 6217534 1543265..1544047 1 NC_010582.1 hypothetical protein 1544047 6217534 SPCG_1572 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836289.1 1543265 D 516950 CDS YP_001836290.1 182684543 6217876 1544173..1545255 1 NC_010582.1 proline dipeptidase 1545255 6217876 SPCG_1573 Streptococcus pneumoniae CGSP14 proline dipeptidase YP_001836290.1 1544173 D 516950 CDS YP_001836291.1 182684544 6216324 complement(1545579..1546412) 1 NC_010582.1 IS3-Spn1, transposase 1546412 6216324 SPCG_1574 Streptococcus pneumoniae CGSP14 IS3-Spn1, transposase YP_001836291.1 1545579 R 516950 CDS YP_001836292.1 182684545 6216359 complement(1546405..1546572) 1 NC_010582.1 degenerate transposase 1546572 6216359 SPCG_1575 Streptococcus pneumoniae CGSP14 degenerate transposase YP_001836292.1 1546405 R 516950 CDS YP_001836293.1 182684546 6216954 complement(1547147..1547608) 1 NC_010582.1 hypothetical protein 1547608 6216954 SPCG_1576 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836293.1 1547147 R 516950 CDS YP_001836294.1 182684547 6218562 complement(1547586..1548359) 1 NC_010582.1 catalyzes the formation of 4-amino-2-methyl-5-diphosphomethylpyrimidine; phosphomethylpyrimidine kinase 1548359 pdxK 6218562 pdxK Streptococcus pneumoniae CGSP14 phosphomethylpyrimidine kinase YP_001836294.1 1547586 R 516950 CDS YP_001836295.1 182684548 6218517 complement(1548349..1549098) 1 NC_010582.1 mediates pseudouridylation (positions 38, 39, 40) at the tRNA anticodon region which contributes to the structural stability; tRNA pseudouridine synthase A 1549098 truA 6218517 truA Streptococcus pneumoniae CGSP14 tRNA pseudouridine synthase A YP_001836295.1 1548349 R 516950 CDS YP_001836296.1 182684549 6218471 1549278..1549439 1 NC_010582.1 cytidylate kinase 1549439 6218471 SPCG_1579 Streptococcus pneumoniae CGSP14 cytidylate kinase YP_001836296.1 1549278 D 516950 CDS YP_001836297.1 182684550 6218327 complement(1549411..1550562) 1 NC_010582.1 hypothetical protein 1550562 6218327 SPCG_1580 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836297.1 1549411 R 516950 CDS YP_001836298.1 182684551 6218505 complement(1550802..1551431) 1 NC_010582.1 hypothetical protein 1551431 6218505 SPCG_1581 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836298.1 1550802 R 516950 CDS YP_001836299.1 182684552 6216389 complement(1551434..1551772) 1 NC_010582.1 phnA protein 1551772 phnA 6216389 phnA Streptococcus pneumoniae CGSP14 phnA protein YP_001836299.1 1551434 R 516950 CDS YP_001836300.1 182684553 6218166 complement(1551903..1552574) 1 NC_010582.1 Catalyzes the formation of (d)CDP from ATP and (d)CMP; cytidylate kinase 1552574 cmk 6218166 cmk Streptococcus pneumoniae CGSP14 cytidylate kinase YP_001836300.1 1551903 R 516950 CDS YP_001836301.1 182684554 6217797 complement(1552583..1553059) 1 NC_010582.1 hypothetical protein 1553059 6217797 SPCG_1584 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836301.1 1552583 R 516950 CDS YP_001836302.1 182684555 6218445 1553111..1553317 1 NC_010582.1 ferredoxin 1553317 6218445 SPCG_1585 Streptococcus pneumoniae CGSP14 ferredoxin YP_001836302.1 1553111 D 516950 CDS YP_001836303.1 182684556 6218448 complement(1553507..1554151) 1 NC_010582.1 hypothetical protein 1554151 6218448 SPCG_1586 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836303.1 1553507 R 516950 CDS YP_001836304.1 182684557 6218379 complement(1554326..1555315) 1 NC_010582.1 glycosyl transferase family protein 1555315 gtrB 6218379 gtrB Streptococcus pneumoniae CGSP14 glycosyl transferase family protein YP_001836304.1 1554326 R 516950 CDS YP_001836305.1 182684558 6217784 complement(1555263..1556282) 1 NC_010582.1 UDP-glucose 4-epimerase 1556282 galE 6217784 galE Streptococcus pneumoniae CGSP14 UDP-glucose 4-epimerase YP_001836305.1 1555263 R 516950 CDS YP_001836306.1 182684559 6216942 complement(1556261..1556410) 1 NC_010582.1 hypothetical protein 1556410 6216942 SPCG_1589 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836306.1 1556261 R 516950 CDS YP_001836307.1 182684560 6218381 complement(1556583..1557695) 1 NC_010582.1 oxidoreductase, DadA family protein 1557695 6218381 SPCG_1590 Streptococcus pneumoniae CGSP14 oxidoreductase, DadA family protein YP_001836307.1 1556583 R 516950 CDS YP_001836308.1 182684561 6216323 complement(1557703..1558500) 1 NC_010582.1 hypothetical protein 1558500 6216323 SPCG_1591 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836308.1 1557703 R 516950 CDS YP_001836309.1 182684562 6218498 complement(1558487..1559164) 1 NC_010582.1 bcl-2 family protein 1559164 6218498 SPCG_1592 Streptococcus pneumoniae CGSP14 bcl-2 family protein YP_001836309.1 1558487 R 516950 CDS YP_001836310.1 182684563 6216424 1559522..1559626 1 NC_010582.1 hypothetical protein 1559626 6216424 SPCG_1593 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836310.1 1559522 D 516950 CDS YP_001836311.1 182684564 6216397 1559713..1560663 1 NC_010582.1 hypothetical protein 1560663 6216397 SPCG_1594 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836311.1 1559713 D 516950 CDS YP_001836312.1 182684565 6217854 1560771..1562216 1 NC_010582.1 hypothetical protein 1562216 6217854 SPCG_1595 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836312.1 1560771 D 516950 CDS YP_001836313.1 182684566 6217807 1562218..1563456 1 NC_010582.1 hypothetical protein 1563456 6217807 SPCG_1596 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836313.1 1562218 D 516950 CDS YP_001836314.1 182684567 6217102 1563645..1566791 1 NC_010582.1 snf2 family protein 1566791 6217102 SPCG_1597 Streptococcus pneumoniae CGSP14 snf2 family protein YP_001836314.1 1563645 D 516950 CDS YP_001836315.1 182684568 6218434 complement(1567228..1569564) 1 NC_010582.1 cation transporter E1-E2 family ATPase 1569564 ctpE 6218434 ctpE Streptococcus pneumoniae CGSP14 cation transporter E1-E2 family ATPase YP_001836315.1 1567228 R 516950 CDS YP_001836316.1 182684569 6218465 1569652..1570446 1 NC_010582.1 acyltransferase family protein 1570446 6218465 SPCG_1599 Streptococcus pneumoniae CGSP14 acyltransferase family protein YP_001836316.1 1569652 D 516950 CDS YP_001836317.1 182684570 6218415 complement(1570738..1571352) 1 NC_010582.1 cadmium resistance transporter 1571352 cadD 6218415 cadD Streptococcus pneumoniae CGSP14 cadmium resistance transporter YP_001836317.1 1570738 R 516950 CDS YP_001836318.1 182684571 6216386 complement(1572168..1572437) 1 NC_010582.1 primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence; 30S ribosomal protein S15 1572437 rpsO 6216386 rpsO Streptococcus pneumoniae CGSP14 30S ribosomal protein S15 YP_001836318.1 1572168 R 516950 CDS YP_001836319.1 182684572 6218404 complement(1572452..1572556) 1 NC_010582.1 hypothetical protein 1572556 6218404 SPCG_1602 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836319.1 1572452 R 516950 CDS YP_001836320.1 182684573 6216420 complement(1572578..1573207) 1 NC_010582.1 hypothetical protein 1573207 6216420 SPCG_1603 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836320.1 1572578 R 516950 CDS YP_001836321.1 182684574 6216437 1573716..1573820 1 NC_010582.1 hypothetical protein 1573820 6216437 SPCG_1604 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836321.1 1573716 D 516950 CDS YP_001836322.1 182684575 6217082 1574011..1574400 1 NC_010582.1 hypothetical protein 1574400 6217082 SPCG_1605 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836322.1 1574011 D 516950 CDS YP_001836323.1 182684576 6218407 1574419..1576401 1 NC_010582.1 catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr); threonyl-tRNA synthetase 1576401 thrS 6218407 thrS Streptococcus pneumoniae CGSP14 threonyl-tRNA synthetase YP_001836323.1 1574419 D 516950 CDS YP_001836324.1 182684577 6218496 complement(1576450..1577424) 1 NC_010582.1 sensor histidine kinase 1577424 6218496 SPCG_1607 Streptococcus pneumoniae CGSP14 sensor histidine kinase YP_001836324.1 1576450 R 516950 CDS YP_001836325.1 182684578 6218190 complement(1577417..1578184) 1 NC_010582.1 DNA-binding response regulator 1578184 6218190 SPCG_1608 Streptococcus pneumoniae CGSP14 DNA-binding response regulator YP_001836325.1 1577417 R 516950 CDS YP_001836326.1 182684579 6218094 1578250..1579323 1 NC_010582.1 hypothetical protein 1579323 6218094 SPCG_1609 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836326.1 1578250 D 516950 CDS YP_001836327.1 182684580 6218143 complement(1579786..1580223) 1 NC_010582.1 rrf2 family protein 1580223 6218143 SPCG_1610 Streptococcus pneumoniae CGSP14 rrf2 family protein YP_001836327.1 1579786 R 516950 CDS YP_001836328.1 182684581 6217866 complement(1580299..1581147) 1 NC_010582.1 hypothetical protein 1581147 6217866 SPCG_1611 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836328.1 1580299 R 516950 CDS YP_001836329.1 182684582 6218126 1581253..1581903 1 NC_010582.1 iron-dependent transcriptional regulator 1581903 6218126 SPCG_1612 Streptococcus pneumoniae CGSP14 iron-dependent transcriptional regulator YP_001836329.1 1581253 D 516950 CDS YP_001836330.1 182684583 6218116 complement(1581975..1583231) 1 NC_010582.1 IS1167, transposase 1583231 6218116 SPCG_1613 Streptococcus pneumoniae CGSP14 IS1167, transposase YP_001836330.1 1581975 R 516950 CDS YP_001836331.1 182684584 6217867 1583502..1584149 1 NC_010582.1 hypothetical protein 1584149 6217867 SPCG_1614 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836331.1 1583502 D 516950 CDS YP_001836332.1 182684585 6217892 1584280..1584693 1 NC_010582.1 hypothetical protein 1584693 6217892 SPCG_1615 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836332.1 1584280 D 516950 CDS YP_001836333.1 182684586 6218140 1584712..1584897 1 NC_010582.1 hypothetical protein 1584897 6218140 SPCG_1616 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836333.1 1584712 D 516950 CDS YP_001836334.1 182684587 6216448 complement(1585164..1585607) 1 NC_010582.1 hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr); possible defense mechanism against a harmful effect of D-tyrosine; D-tyrosyl-tRNA(Tyr) deacylase 1585607 6216448 SPCG_1617 Streptococcus pneumoniae CGSP14 D-tyrosyl-tRNA(Tyr) deacylase YP_001836334.1 1585164 R 516950 CDS YP_001836335.1 182684588 6217296 complement(1585637..1587859) 1 NC_010582.1 GTP pyrophosphokinase 1587859 relA 6217296 relA Streptococcus pneumoniae CGSP14 GTP pyrophosphokinase YP_001836335.1 1585637 R 516950 CDS YP_001836336.1 182684589 6216915 1588767..1589447 1 NC_010582.1 metallo-beta-lactamase superfamily protein 1589447 6216915 SPCG_1619 Streptococcus pneumoniae CGSP14 metallo-beta-lactamase superfamily protein YP_001836336.1 1588767 D 516950 CDS YP_001836337.1 182684590 6216833 complement(1589570..1591522) 1 NC_010582.1 endopeptidase O 1591522 pepO 6216833 pepO Streptococcus pneumoniae CGSP14 endopeptidase O YP_001836337.1 1589570 R 516950 CDS YP_001836338.1 182684591 6217085 1591720..1592475 1 NC_010582.1 manganese ABC transporter ATP-binding protein 1592475 6217085 SPCG_1621 Streptococcus pneumoniae CGSP14 manganese ABC transporter ATP-binding protein YP_001836338.1 1591720 D 516950 CDS YP_001836339.1 182684592 6216934 1592472..1593320 1 NC_010582.1 manganese ABC transporter permease 1593320 6216934 SPCG_1622 Streptococcus pneumoniae CGSP14 manganese ABC transporter permease YP_001836339.1 1592472 D 516950 CDS YP_001836340.1 182684593 6216878 1593340..1594281 1 NC_010582.1 manganese ABC transporter manganese-binding adhesion liprotein 1594281 6216878 SPCG_1623 Streptococcus pneumoniae CGSP14 manganese ABC transporter manganese-binding adhesion liprotein YP_001836340.1 1593340 D 516950 CDS YP_001836341.1 182684594 6217009 1594377..1594895 1 NC_010582.1 antioxidant activity; thioredoxin-dependent thiol peroxidase; forms homodimers in solution; shows substrate specificity to alkyl hydroperoxides; periplasmic protein; thiol peroxidase 1594895 tpx 6217009 tpx Streptococcus pneumoniae CGSP14 thiol peroxidase YP_001836341.1 1594377 D 516950 CDS YP_001836342.1 182684595 6217749 complement(1594991..1597765) 1 NC_010582.1 hypothetical protein 1597765 6217749 SPCG_1625 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836342.1 1594991 R 516950 CDS YP_001836343.1 182684596 6217928 complement(1597701..1598411) 1 NC_010582.1 ABC transporter ATP-binding protein 1598411 6217928 SPCG_1626 Streptococcus pneumoniae CGSP14 ABC transporter ATP-binding protein YP_001836343.1 1597701 R 516950 CDS YP_001836344.1 182684597 6216680 complement(1598652..1601063) 1 NC_010582.1 hypothetical protein 1601063 6216680 SPCG_1627 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836344.1 1598652 R 516950 CDS YP_001836345.1 182684598 6217497 complement(1601116..1601808) 1 NC_010582.1 2,3-bisphosphoglycerate-dependent; catalyzes the interconversion of 2-phosphoglycerate to 3-phosphoglycerate; phosphoglyceromutase 1601808 gpmA 6217497 gpmA Streptococcus pneumoniae CGSP14 phosphoglyceromutase YP_001836345.1 1601116 R 516950 CDS YP_001836346.1 182684599 6217208 complement(1601859..1602149) 1 NC_010582.1 hypothetical protein 1602149 6217208 SPCG_1629 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836346.1 1601859 R 516950 CDS YP_001836347.1 182684600 6216799 complement(1602343..1602723) 1 NC_010582.1 integral membrane protein 1602723 6216799 SPCG_1630 Streptococcus pneumoniae CGSP14 integral membrane protein YP_001836347.1 1602343 R 516950 CDS YP_001836348.1 182684601 6216800 complement(1603126..1605918) 1 NC_010582.1 IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase family type 1 subfamily; some organisms carry two different copies of this enzyme; isoleucyl-tRNA synthetase 1605918 ileS 6216800 ileS Streptococcus pneumoniae CGSP14 isoleucyl-tRNA synthetase YP_001836348.1 1603126 R 516950 CDS YP_001836349.1 182684602 6218292 complement(1606171..1606287) 1 NC_010582.1 hypothetical protein 1606287 6218292 SPCG_1632 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836349.1 1606171 R 516950 CDS YP_001836350.1 182684603 6218186 complement(1606266..1607066) 1 NC_010582.1 cell division protein DivIVA 1607066 6218186 SPCG_1633 Streptococcus pneumoniae CGSP14 cell division protein DivIVA YP_001836350.1 1606266 R 516950 CDS YP_001836351.1 182684604 6217185 complement(1607063..1607848) 1 NC_010582.1 ylmH protein 1607848 divIVA 6217185 divIVA Streptococcus pneumoniae CGSP14 ylmH protein YP_001836351.1 1607063 R 516950 CDS YP_001836352.1 182684605 6217506 complement(1607845..1608108) 1 NC_010582.1 ylmG protein 1608108 6217506 SPCG_1635 Streptococcus pneumoniae CGSP14 ylmG protein YP_001836352.1 1607845 R 516950 CDS YP_001836353.1 182684606 6218223 complement(1608108..1608647) 1 NC_010582.1 ylmF protein 1608647 6218223 SPCG_1636 Streptococcus pneumoniae CGSP14 ylmF protein YP_001836353.1 1608108 R 516950 CDS YP_001836354.1 182684607 6217540 complement(1608657..1609328) 1 NC_010582.1 ylmE protein 1609328 6217540 SPCG_1637 Streptococcus pneumoniae CGSP14 ylmE protein YP_001836354.1 1608657 R 516950 CDS YP_001836355.1 182684608 6217225 complement(1609333..1610592) 1 NC_010582.1 GTPase; similar structure to tubulin; forms ring-shaped polymers at the site of cell division; other proteins such as FtsA, ZipA, and ZapA, interact with and regulate FtsZ function; cell division protein FtsZ 1610592 6217225 SPCG_1638 Streptococcus pneumoniae CGSP14 cell division protein FtsZ YP_001836355.1 1609333 R 516950 CDS YP_001836356.1 182684609 6218435 complement(1610609..1611982) 1 NC_010582.1 cell division protein FtsA 1611982 ftsZ 6218435 ftsZ Streptococcus pneumoniae CGSP14 cell division protein FtsA YP_001836356.1 1610609 R 516950 CDS YP_001836357.1 182684610 6218439 complement(1612201..1612905) 1 NC_010582.1 hypothetical protein 1612905 ftsA 6218439 ftsA Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836357.1 1612201 R 516950 CDS YP_001836358.1 182684611 6217529 complement(1612996..1613607) 1 NC_010582.1 mutT/nudix family protein 1613607 6217529 SPCG_1641 Streptococcus pneumoniae CGSP14 mutT/nudix family protein YP_001836358.1 1612996 R 516950 CDS YP_001836359.1 182684612 6217155 complement(1613594..1614967) 1 NC_010582.1 UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6- diaminopimelate--D-alanyl-D-alanine ligase 1614967 mutT 6217155 mutT Streptococcus pneumoniae CGSP14 UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6- diaminopimelate--D-alanyl-D-alanine ligase YP_001836359.1 1613594 R 516950 CDS YP_001836360.1 182684613 6217625 complement(1615051..1616094) 1 NC_010582.1 D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli; D-alanyl-alanine synthetase A 1616094 ddl 6217625 ddl Streptococcus pneumoniae CGSP14 D-alanyl-alanine synthetase A YP_001836360.1 1615051 R 516950 CDS YP_001836361.1 182684614 6217425 complement(1616270..1616866) 1 NC_010582.1 involved in a recombinational process of DNA repair, independent of the recBC complex; recombination protein RecR 1616866 recR 6217425 recR Streptococcus pneumoniae CGSP14 recombination protein RecR YP_001836361.1 1616270 R 516950 CDS YP_001836362.1 182684615 6216620 complement(1616877..1618934) 1 NC_010582.1 penicillin-binding protein 2B 1618934 pbp2B 6216620 pbp2B Streptococcus pneumoniae CGSP14 penicillin-binding protein 2B YP_001836362.1 1616877 R 516950 CDS YP_001836363.1 182684616 6216447 1619128..1619979 1 NC_010582.1 phosphosugar-binding transcriptional regulator 1619979 6216447 SPCG_1646 Streptococcus pneumoniae CGSP14 phosphosugar-binding transcriptional regulator YP_001836363.1 1619128 D 516950 CDS YP_001836364.1 182684617 6217040 complement(1619995..1620879) 1 NC_010582.1 ROK family protein 1620879 6217040 SPCG_1647 Streptococcus pneumoniae CGSP14 ROK family protein YP_001836364.1 1619995 R 516950 CDS YP_001836365.1 182684618 6217880 complement(1620897..1621814) 1 NC_010582.1 N-acetylneuraminate lyase 1621814 6217880 SPCG_1648 Streptococcus pneumoniae CGSP14 N-acetylneuraminate lyase YP_001836365.1 1620897 R 516950 CDS YP_001836366.1 182684619 6216538 complement(1621983..1622627) 1 NC_010582.1 hypothetical protein 1622627 6216538 SPCG_1649 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836366.1 1621983 R 516950 CDS YP_001836367.1 182684620 6216749 complement(1622609..1622707) 1 NC_010582.1 hypothetical protein 1622707 6216749 SPCG_1650 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836367.1 1622609 R 516950 CDS YP_001836368.1 182684621 6218375 complement(1622904..1623248) 1 NC_010582.1 hypothetical protein 1623248 6218375 SPCG_1651 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836368.1 1622904 R 516950 CDS YP_001836369.1 182684622 6217650 complement(1623345..1623797) 1 NC_010582.1 hypothetical protein 1623797 6217650 SPCG_1652 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836369.1 1623345 R 516950 CDS YP_001836370.1 182684623 6217115 complement(1623821..1623973) 1 NC_010582.1 hypothetical protein 1623973 6217115 SPCG_1653 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836370.1 1623821 R 516950 CDS YP_001836371.1 182684624 6218169 complement(1624069..1624908) 1 NC_010582.1 sugar ABC transporter permease 1624908 6218169 SPCG_1654 Streptococcus pneumoniae CGSP14 sugar ABC transporter permease YP_001836371.1 1624069 R 516950 CDS YP_001836372.1 182684625 6217914 complement(1624924..1625820) 1 NC_010582.1 sugar ABC transporter permease 1625820 6217914 SPCG_1655 Streptococcus pneumoniae CGSP14 sugar ABC transporter permease YP_001836372.1 1624924 R 516950 CDS YP_001836373.1 182684626 6216997 complement(1626042..1627370) 1 NC_010582.1 sugar ABC transporter sugar-binding protein 1627370 6216997 SPCG_1656 Streptococcus pneumoniae CGSP14 sugar ABC transporter sugar-binding protein YP_001836373.1 1626042 R 516950 CDS YP_001836374.1 182684627 6217959 complement(1627495..1629027) 1 NC_010582.1 PTS system transporter subunit IIBC 1629027 6217959 SPCG_1657 Streptococcus pneumoniae CGSP14 PTS system transporter subunit IIBC YP_001836374.1 1627495 R 516950 CDS YP_001836375.1 182684628 6217351 complement(1629031..1629729) 1 NC_010582.1 Converts N-acetylmannosamine-6-phosphate to N-acetylglucosamine-6-phosphate; N-acetylmannosamine-6-phosphate 2-epimerase 1629729 nanE 6217351 nanE Streptococcus pneumoniae CGSP14 N-acetylmannosamine-6-phosphate 2-epimerase YP_001836375.1 1629031 R 516950 CDS YP_001836376.1 182684629 6216596 complement(1629903..1631006) 1 NC_010582.1 Gfo/Idh/MocA family oxidoreductase 1631006 6216596 SPCG_1659 Streptococcus pneumoniae CGSP14 Gfo/Idh/MocA family oxidoreductase YP_001836376.1 1629903 R 516950 CDS YP_001836377.1 182684630 6217694 complement(1631018..1633111) 1 NC_010582.1 neuraminidase B 1633111 nanB 6217694 nanB Streptococcus pneumoniae CGSP14 neuraminidase B YP_001836377.1 1631018 R 516950 CDS YP_001836378.1 182684631 6216824 complement(1633129..1633962) 1 NC_010582.1 ABC transporter permease 1633962 6216824 SPCG_1661 Streptococcus pneumoniae CGSP14 ABC transporter permease YP_001836378.1 1633129 R 516950 CDS YP_001836379.1 182684632 6216812 complement(1633962..1634846) 1 NC_010582.1 ABC transporter permease 1634846 6216812 SPCG_1662 Streptococcus pneumoniae CGSP14 ABC transporter permease YP_001836379.1 1633962 R 516950 CDS YP_001836380.1 182684633 6217422 complement(1634925..1636262) 1 NC_010582.1 ABC transporter substrate-binding protein 1636262 6217422 SPCG_1663 Streptococcus pneumoniae CGSP14 ABC transporter substrate-binding protein YP_001836380.1 1634925 R 516950 CDS YP_001836381.1 182684634 6217812 complement(1636281..1636733) 1 NC_010582.1 hypothetical protein 1636733 6217812 SPCG_1664 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836381.1 1636281 R 516950 CDS YP_001836382.1 182684635 6217600 complement(1637747..1640689) 1 NC_010582.1 sialidase A (neuraminidase A) 1640689 nanA 6217600 nanA Streptococcus pneumoniae CGSP14 sialidase A (neuraminidase A) YP_001836382.1 1637747 R 516950 CDS YP_001836383.1 182684636 6216599 complement(1640932..1641159) 1 NC_010582.1 hypothetical protein 1641159 6216599 SPCG_1666 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836383.1 1640932 R 516950 CDS YP_001836384.1 182684637 6217647 complement(1641433..1642095) 1 NC_010582.1 hypothetical protein 1642095 6217647 SPCG_1667 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836384.1 1641433 R 516950 CDS YP_001836385.1 182684638 6217576 complement(1642414..1643394) 1 NC_010582.1 acetyl xylan esterase 1643394 axe1 6217576 axe1 Streptococcus pneumoniae CGSP14 acetyl xylan esterase YP_001836385.1 1642414 R 516950 CDS YP_001836386.1 182684639 6218073 complement(1643951..1645966) 1 NC_010582.1 catalyzes branch migration in Holliday junction intermediates; ATP-dependent DNA helicase RecG 1645966 recG 6218073 recG Streptococcus pneumoniae CGSP14 ATP-dependent DNA helicase RecG YP_001836386.1 1643951 R 516950 CDS YP_001836387.1 182684640 6217624 complement(1645985..1647109) 1 NC_010582.1 converts L-alanine to D-alanine which is used in cell wall biosynthesis; binds one pyridoxal phosphate per monomer; forms a homodimer; alanine racemase 1647109 alr 6217624 alr Streptococcus pneumoniae CGSP14 alanine racemase YP_001836387.1 1645985 R 516950 CDS YP_001836388.1 182684641 6217207 complement(1647078..1647449) 1 NC_010582.1 Catalyzes the formation of holo-ACP, which mediates the essential transfer of acyl fatty acid intermediates during the biosynthesis of fatty acids and lipids; 4'-phosphopantetheinyl transferase 1647449 acpS 6217207 acpS Streptococcus pneumoniae CGSP14 4'-phosphopantetheinyl transferase YP_001836388.1 1647078 R 516950 CDS YP_001836389.1 182684642 6218597 complement(1647485..1648516) 1 NC_010582.1 catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, phenylalanine sensitive; phospho-2-dehydro-3-deoxyheptonate aldolase 1648516 aroF 6218597 aroF Streptococcus pneumoniae CGSP14 phospho-2-dehydro-3-deoxyheptonate aldolase YP_001836389.1 1647485 R 516950 CDS YP_001836390.1 182684643 6217411 complement(1648518..1649549) 1 NC_010582.1 catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, tyrosine sensitive; phospho-2-dehydro-3-deoxyheptonate aldolase 1649549 aroG 6217411 aroG Streptococcus pneumoniae CGSP14 phospho-2-dehydro-3-deoxyheptonate aldolase YP_001836390.1 1648518 R 516950 CDS YP_001836391.1 182684644 6216823 complement(1649630..1652143) 1 NC_010582.1 functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond SecA1; SecA2 is not essential and seems to play a role in secretion of a subset of proteins; preprotein translocase subunit SecA 1652143 secA 6216823 secA Streptococcus pneumoniae CGSP14 preprotein translocase subunit SecA YP_001836391.1 1649630 R 516950 CDS YP_001836392.1 182684645 6216932 complement(1652289..1652576) 1 NC_010582.1 hypothetical protein 1652576 6216932 SPCG_1675 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836392.1 1652289 R 516950 CDS YP_001836393.1 182684646 6217071 complement(1652587..1653237) 1 NC_010582.1 ABC transporter ATP-binding protein 1653237 6217071 SPCG_1676 Streptococcus pneumoniae CGSP14 ABC transporter ATP-binding protein YP_001836393.1 1652587 R 516950 CDS YP_001836394.1 182684647 6216731 complement(1653241..1653921) 1 NC_010582.1 hypothetical protein 1653921 6216731 SPCG_1677 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836394.1 1653241 R 516950 CDS YP_001836395.1 182684648 6217696 complement(1653875..1654705) 1 NC_010582.1 hypothetical protein 1654705 6217696 SPCG_1678 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836395.1 1653875 R 516950 CDS YP_001836396.1 182684649 6217623 complement(1654851..1655189) 1 NC_010582.1 hypothetical protein 1655189 6217623 SPCG_1679 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836396.1 1654851 R 516950 CDS YP_001836397.1 182684650 6218581 complement(1655327..1655674) 1 NC_010582.1 hypothetical protein 1655674 6218581 SPCG_1680 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836397.1 1655327 R 516950 CDS YP_001836398.1 182684651 6217334 complement(1655753..1657063) 1 NC_010582.1 EngA; essential Neisserial GTPase; synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains; GTP-binding protein EngA 1657063 engA 6217334 engA Streptococcus pneumoniae CGSP14 GTP-binding protein EngA YP_001836398.1 1655753 R 516950 CDS YP_001836399.1 182684652 6218258 complement(1657077..1657790) 1 NC_010582.1 nitroreductase family protein 1657790 6218258 SPCG_1682 Streptococcus pneumoniae CGSP14 nitroreductase family protein YP_001836399.1 1657077 R 516950 CDS YP_001836400.1 182684653 6217409 complement(1657787..1658683) 1 NC_010582.1 Primosomal protein that may act to load helicase DnaC during DNA replication; primosomal protein DnaI 1658683 dnaI 6217409 dnaI Streptococcus pneumoniae CGSP14 primosomal protein DnaI YP_001836400.1 1657787 R 516950 CDS YP_001836401.1 182684654 6216522 complement(1658684..1659853) 1 NC_010582.1 hypothetical protein 1659853 6216522 SPCG_1684 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836401.1 1658684 R 516950 CDS YP_001836402.1 182684655 6216660 complement(1659854..1660387) 1 NC_010582.1 NrdR family transcriptional regulator 1660387 nrdR 6216660 nrdR Streptococcus pneumoniae CGSP14 NrdR family transcriptional regulator YP_001836402.1 1659854 R 516950 CDS YP_001836403.1 182684656 6217423 1660467..1660832 1 NC_010582.1 GntR family transcriptional regulator 1660832 6217423 SPCG_1686 Streptococcus pneumoniae CGSP14 GntR family transcriptional regulator YP_001836403.1 1660467 D 516950 CDS YP_001836404.1 182684657 6218098 1660810..1661532 1 NC_010582.1 ABC transporter ATP-binding protein 1661532 6218098 SPCG_1687 Streptococcus pneumoniae CGSP14 ABC transporter ATP-binding protein YP_001836404.1 1660810 D 516950 CDS YP_001836405.1 182684658 6218159 1661468..1662316 1 NC_010582.1 ABC transporter ATP-binding protein 1662316 6218159 SPCG_1688 Streptococcus pneumoniae CGSP14 ABC transporter ATP-binding protein YP_001836405.1 1661468 D 516950 CDS YP_001836406.1 182684659 6218080 complement(1662669..1663868) 1 NC_010582.1 hypothetical protein 1663868 6218080 SPCG_1689 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836406.1 1662669 R 516950 CDS YP_001836407.1 182684660 6217055 complement(1663865..1664758) 1 NC_010582.1 ABC transporter ATP-binding protein 1664758 6217055 SPCG_1690 Streptococcus pneumoniae CGSP14 ABC transporter ATP-binding protein YP_001836407.1 1663865 R 516950 CDS YP_001836408.1 182684661 6218141 complement(1665149..1665250) 1 NC_010582.1 hypothetical protein 1665250 6218141 SPCG_1691 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836408.1 1665149 R 516950 CDS YP_001836409.1 182684662 6216865 1666068..1666685 1 NC_010582.1 hypothetical protein 1666685 6216865 SPCG_1692 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836409.1 1666068 D 516950 CDS YP_001836410.1 182684663 6216426 complement(1666728..1667615) 1 NC_010582.1 fructokinase 1667615 scrK 6216426 scrK Streptococcus pneumoniae CGSP14 fructokinase YP_001836410.1 1666728 R 516950 CDS YP_001836411.1 182684664 6216894 complement(1667764..1669725) 1 NC_010582.1 PTS system IIABC components 1669725 scrA 6216894 scrA Streptococcus pneumoniae CGSP14 PTS system IIABC components YP_001836411.1 1667764 R 516950 CDS YP_001836412.1 182684665 6217303 complement(1669827..1670024) 1 NC_010582.1 hypothetical protein 1670024 6217303 SPCG_1695 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836412.1 1669827 R 516950 CDS YP_001836413.1 182684666 6217545 1670077..1671531 1 NC_010582.1 sucrose-6-phosphate hydrolase 1671531 scrB 6217545 scrB Streptococcus pneumoniae CGSP14 sucrose-6-phosphate hydrolase YP_001836413.1 1670077 D 516950 CDS YP_001836414.1 182684667 6218284 1671512..1672477 1 NC_010582.1 sucrose operon repressor 1672477 scrR 6218284 scrR Streptococcus pneumoniae CGSP14 sucrose operon repressor YP_001836414.1 1671512 D 516950 CDS YP_001836415.1 182684668 6218114 complement(1672512..1673786) 1 NC_010582.1 3-hydroxy-3-methylglutaryl-CoA reductase 1673786 mvaA 6218114 mvaA Streptococcus pneumoniae CGSP14 3-hydroxy-3-methylglutaryl-CoA reductase YP_001836415.1 1672512 R 516950 CDS YP_001836416.1 182684669 6217717 complement(1673786..1674982) 1 NC_010582.1 hydroxymethylglutaryl-CoA synthase 1674982 mvaS 6217717 mvaS Streptococcus pneumoniae CGSP14 hydroxymethylglutaryl-CoA synthase YP_001836416.1 1673786 R 516950 CDS YP_001836417.1 182684670 6218059 complement(1675089..1675376) 1 NC_010582.1 hypothetical protein 1675376 6218059 SPCG_1700 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836417.1 1675089 R 516950 CDS YP_001836418.1 182684671 6217396 complement(1675405..1675794) 1 NC_010582.1 IS1381 transposase protein B 1675794 6217396 SPCG_1701 Streptococcus pneumoniae CGSP14 IS1381 transposase protein B YP_001836418.1 1675405 R 516950 CDS YP_001836419.1 182684672 6217295 complement(1675828..1676028) 1 NC_010582.1 IS1381 transposase protein A, truncation 1676028 6217295 SPCG_1702 Streptococcus pneumoniae CGSP14 IS1381 transposase protein A, truncation YP_001836419.1 1675828 R 516950 CDS YP_001836420.1 182684673 6218286 complement(1676093..1676542) 1 NC_010582.1 hypothetical protein 1676542 6218286 SPCG_1703 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836420.1 1676093 R 516950 CDS YP_001836421.1 182684674 6218277 complement(1676544..1677302) 1 NC_010582.1 hypothetical protein 1677302 6218277 SPCG_1704 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836421.1 1676544 R 516950 CDS YP_001836422.1 182684675 6216473 complement(1677417..1679396) 1 NC_010582.1 serine/threonine protein kinase 1679396 pkn2 6216473 pkn2 Streptococcus pneumoniae CGSP14 serine/threonine protein kinase YP_001836422.1 1677417 R 516950 CDS YP_001836423.1 182684676 6217186 complement(1679393..1680133) 1 NC_010582.1 phosphatase 1680133 pppL 6217186 pppL Streptococcus pneumoniae CGSP14 phosphatase YP_001836423.1 1679393 R 516950 CDS YP_001836424.1 182684677 6216843 complement(1680148..1681464) 1 NC_010582.1 rRNA methyltransferase RsmB 1681464 sunL 6216843 sunL Streptococcus pneumoniae CGSP14 rRNA methyltransferase RsmB YP_001836424.1 1680148 R 516950 CDS YP_001836425.1 182684678 6217758 complement(1681454..1682389) 1 NC_010582.1 modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet) which is important in translation initiation; inactivation of this gene in Escherichia coli severely impairs growth; methionyl-tRNA formyltransferase 1682389 fmt 6217758 fmt Streptococcus pneumoniae CGSP14 methionyl-tRNA formyltransferase YP_001836425.1 1681454 R 516950 CDS YP_001836426.1 182684679 6218228 complement(1682402..1683376) 1 NC_010582.1 primosome assembly protein PriA 1683376 6218228 SPCG_1709 Streptococcus pneumoniae CGSP14 primosome assembly protein PriA YP_001836426.1 1682402 R 516950 CDS YP_001836427.1 182684680 6216421 complement(1683370..1684797) 1 NC_010582.1 primosome assembly protein PriA 1684797 6216421 SPCG_1710 Streptococcus pneumoniae CGSP14 primosome assembly protein PriA YP_001836427.1 1683370 R 516950 CDS YP_001836428.1 182684681 6217878 complement(1684863..1685177) 1 NC_010582.1 Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits; DNA-directed RNA polymerase subunit omega 1685177 6217878 SPCG_1711 Streptococcus pneumoniae CGSP14 DNA-directed RNA polymerase subunit omega YP_001836428.1 1684863 R 516950 CDS YP_001836429.1 182684682 6217653 complement(1685202..1685828) 1 NC_010582.1 Essential for recycling GMP and indirectly, cGMP; guanylate kinase 1685828 gmk 6217653 gmk Streptococcus pneumoniae CGSP14 guanylate kinase YP_001836429.1 1685202 R 516950 CDS YP_001836430.1 182684683 6217557 complement(1685958..1687571) 1 NC_010582.1 hypothetical protein 1687571 6217557 SPCG_1713 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836430.1 1685958 R 516950 CDS YP_001836431.1 182684684 6218507 complement(1687762..1688016) 1 NC_010582.1 hypothetical protein 1688016 6218507 SPCG_1714 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836431.1 1687762 R 516950 CDS YP_001836432.1 182684685 6218417 complement(1688020..1688313) 1 NC_010582.1 hypothetical protein 1688313 6218417 SPCG_1715 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836432.1 1688020 R 516950 CDS YP_001836433.1 182684686 6218570 complement(1688512..1689609) 1 NC_010582.1 hypothetical protein 1689609 6218570 SPCG_1716 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836433.1 1688512 R 516950 CDS YP_001836434.1 182684687 6216641 complement(1689619..1690374) 1 NC_010582.1 hypothetical protein 1690374 6216641 SPCG_1717 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836434.1 1689619 R 516950 CDS YP_001836435.1 182684688 6216537 complement(1690679..1691032) 1 NC_010582.1 iojap-like protein 1691032 6216537 SPCG_1718 Streptococcus pneumoniae CGSP14 iojap-like protein YP_001836435.1 1690679 R 516950 CDS YP_001836436.1 182684689 6218104 complement(1691045..1691545) 1 NC_010582.1 isochorismatase family protein 1691545 6218104 SPCG_1719 Streptococcus pneumoniae CGSP14 isochorismatase family protein YP_001836436.1 1691045 R 516950 CDS YP_001836437.1 182684690 6218147 complement(1691546..1692139) 1 NC_010582.1 hypothetical protein 1692139 6218147 SPCG_1720 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836437.1 1691546 R 516950 CDS YP_001836438.1 182684691 6217589 complement(1692139..1692768) 1 NC_010582.1 transfers an adenyl group from ATP to NaMN to form nicotinic acid adenine dinucleotide (NaAD) which is then converted to the ubiquitous compound NAD by NAD synthetase; essential enzyme in bacteria; nicotinic acid mononucleotide adenylyltransferase 1692768 nadD 6217589 nadD Streptococcus pneumoniae CGSP14 nicotinic acid mononucleotide adenylyltransferase YP_001836438.1 1692139 R 516950 CDS YP_001836439.1 182684692 6216718 complement(1692820..1693131) 1 NC_010582.1 hypothetical protein 1693131 6216718 SPCG_1722 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836439.1 1692820 R 516950 CDS YP_001836440.1 182684693 6216403 complement(1693331..1694437) 1 NC_010582.1 in Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis; GTP-binding protein YqeH 1694437 6216403 SPCG_1723 Streptococcus pneumoniae CGSP14 GTP-binding protein YqeH YP_001836440.1 1693331 R 516950 CDS YP_001836441.1 182684694 6217154 complement(1694440..1695030) 1 NC_010582.1 hypothetical protein 1695030 6217154 SPCG_1724 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836441.1 1694440 R 516950 CDS YP_001836442.1 182684695 6217050 complement(1694982..1695890) 1 NC_010582.1 CorA family protein 1695890 corA 6217050 corA Streptococcus pneumoniae CGSP14 CorA family protein YP_001836442.1 1694982 R 516950 CDS YP_001836443.1 182684696 6218544 complement(1695947..1696552) 1 NC_010582.1 mechanosensitive ion channel 1696552 6218544 SPCG_1726 Streptococcus pneumoniae CGSP14 mechanosensitive ion channel YP_001836443.1 1695947 R 516950 CDS YP_001836444.1 182684697 6218356 1696896..1697855 1 NC_010582.1 involved in the import of serine and threonine coupled with the import of sodium; serine/threonine transporter SstT 1697855 dctA 6218356 dctA Streptococcus pneumoniae CGSP14 serine/threonine transporter SstT YP_001836444.1 1696896 D 516950 CDS YP_001836445.1 182684698 6218595 1697923..1698876 1 NC_010582.1 hypothetical protein 1698876 6218595 SPCG_1728 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836445.1 1697923 D 516950 CDS YP_001836446.1 182684699 6216786 complement(1698893..1699132) 1 NC_010582.1 hypothetical protein 1699132 6216786 SPCG_1729 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836446.1 1698893 R 516950 CDS YP_001836447.1 182684700 6217551 1699243..1700535 1 NC_010582.1 IS1167, transposase 1700535 6217551 SPCG_1730 Streptococcus pneumoniae CGSP14 IS1167, transposase YP_001836447.1 1699243 D 516950 CDS YP_001836448.1 182684701 6217256 complement(1700578..1700802) 1 NC_010582.1 hypothetical protein 1700802 6217256 SPCG_1731 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836448.1 1700578 R 516950 CDS YP_001836449.1 182684702 6217188 complement(1700807..1700986) 1 NC_010582.1 hypothetical protein 1700986 6217188 SPCG_1732 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836449.1 1700807 R 516950 CDS YP_001836450.1 182684703 6217170 complement(1700988..1702325) 1 NC_010582.1 hypothetical protein 1702325 6217170 SPCG_1733 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836450.1 1700988 R 516950 CDS YP_001836451.1 182684704 6217676 complement(1702318..1703829) 1 NC_010582.1 group 1 glycosyl transferase 1703829 6217676 SPCG_1734 Streptococcus pneumoniae CGSP14 group 1 glycosyl transferase YP_001836451.1 1702318 R 516950 CDS YP_001836452.1 182684705 6216631 complement(1703841..1706213) 1 NC_010582.1 functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; in some organisms, especially gram positive pathogens, have paralogs that have been found to be nonessential but do function in secretion of a subset of exported proteins; preprotein translocase subunit SecA 1706213 6216631 SPCG_1735 Streptococcus pneumoniae CGSP14 preprotein translocase subunit SecA YP_001836452.1 1703841 R 516950 CDS YP_001836453.1 182684706 6216886 complement(1706206..1706646) 1 NC_010582.1 hypothetical protein 1706646 6216886 SPCG_1736 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836453.1 1706206 R 516950 CDS YP_001836454.1 182684707 6217455 complement(1706643..1708178) 1 NC_010582.1 hypothetical protein 1708178 6217455 SPCG_1737 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836454.1 1706643 R 516950 CDS YP_001836455.1 182684708 6218532 complement(1708162..1709742) 1 NC_010582.1 hypothetical protein 1709742 6218532 SPCG_1738 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836455.1 1708162 R 516950 CDS YP_001836456.1 182684709 6217214 complement(1709752..1710969) 1 NC_010582.1 forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase; preprotein translocase subunit SecY 1710969 secY 6217214 secY Streptococcus pneumoniae CGSP14 preprotein translocase subunit SecY YP_001836456.1 1709752 R 516950 CDS YP_001836457.1 182684710 6216888 complement(1711026..1711703) 1 NC_010582.1 glycosyl transferase family protein 1711703 6216888 SPCG_1740 Streptococcus pneumoniae CGSP14 glycosyl transferase family protein YP_001836457.1 1711026 R 516950 CDS YP_001836458.1 182684711 6216482 complement(1711930..1713126) 1 NC_010582.1 glycosyl transferase family protein 1713126 6216482 SPCG_1741 Streptococcus pneumoniae CGSP14 glycosyl transferase family protein YP_001836458.1 1711930 R 516950 CDS YP_001836459.1 182684712 6216658 complement(1713135..1714355) 1 NC_010582.1 glycosyl transferase family protein 1714355 6216658 SPCG_1742 Streptococcus pneumoniae CGSP14 glycosyl transferase family protein YP_001836459.1 1713135 R 516950 CDS YP_001836460.1 182684713 6217836 complement(1714386..1716830) 1 NC_010582.1 glycosyl transferase family protein 1716830 6217836 SPCG_1743 Streptococcus pneumoniae CGSP14 glycosyl transferase family protein YP_001836460.1 1714386 R 516950 CDS YP_001836461.1 182684714 6218167 complement(1716840..1717850) 1 NC_010582.1 hypothetical protein 1717850 6218167 SPCG_1744 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836461.1 1716840 R 516950 CDS YP_001836462.1 182684715 6216728 complement(1717890..1719095) 1 NC_010582.1 glycosyl transferase family protein 1719095 6216728 SPCG_1745 Streptococcus pneumoniae CGSP14 glycosyl transferase family protein YP_001836462.1 1717890 R 516950 CDS YP_001836463.1 182684716 6216556 complement(1719104..1719979) 1 NC_010582.1 glycosyl transferase family protein 1719979 6216556 SPCG_1746 Streptococcus pneumoniae CGSP14 glycosyl transferase family protein YP_001836463.1 1719104 R 516950 CDS YP_001836464.1 182684717 6217469 complement(1720434..1721192) 1 NC_010582.1 hypothetical protein 1721192 6217469 SPCG_1747 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836464.1 1720434 R 516950 CDS YP_001836465.1 182684718 6217161 complement(1721202..1722080) 1 NC_010582.1 exopolysaccharide biosynthesis acetyltransferase 1722080 6217161 SPCG_1748 Streptococcus pneumoniae CGSP14 exopolysaccharide biosynthesis acetyltransferase YP_001836465.1 1721202 R 516950 CDS YP_001836466.1 182684719 6217748 complement(1722077..1724167) 1 NC_010582.1 glycosyl transferase family protein 1724167 6217748 SPCG_1749 Streptococcus pneumoniae CGSP14 glycosyl transferase family protein YP_001836466.1 1722077 R 516950 CDS YP_001836467.1 182684720 6217791 complement(1724222..1738309) 1 NC_010582.1 cell wall surface anchor family protein 1738309 6217791 SPCG_1750 Streptococcus pneumoniae CGSP14 cell wall surface anchor family protein YP_001836467.1 1724222 R 516950 CDS YP_001836468.1 182684721 6217921 complement(1738670..1739131) 1 NC_010582.1 degenerate transposase 1739131 6217921 SPCG_1751 Streptococcus pneumoniae CGSP14 degenerate transposase YP_001836468.1 1738670 R 516950 CDS YP_001836469.1 182684722 6217160 1739464..1739889 1 NC_010582.1 transcriptional regulator 1739889 6217160 SPCG_1752 Streptococcus pneumoniae CGSP14 transcriptional regulator YP_001836469.1 1739464 D 516950 CDS YP_001836470.1 182684723 6216673 1739907..1740209 1 NC_010582.1 hypothetical protein 1740209 6216673 SPCG_1753 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836470.1 1739907 D 516950 CDS YP_001836471.1 182684724 6218085 1740226..1740540 1 NC_010582.1 thioredoxin 1740540 trxA 6218085 trxA Streptococcus pneumoniae CGSP14 thioredoxin YP_001836471.1 1740226 D 516950 CDS YP_001836472.1 182684725 6217530 1740807..1741379 1 NC_010582.1 NADPH-dependent; catalyzes the reduction of 7-cyano-7-deazaguanine to 7-aminomethyl-7-deazaguanine in queuosine biosynthesis; 7-cyano-7-deazaguanine reductase 1741379 6217530 SPCG_1755 Streptococcus pneumoniae CGSP14 7-cyano-7-deazaguanine reductase YP_001836472.1 1740807 D 516950 CDS YP_001836473.1 182684726 6217259 complement(1741634..1742302) 1 NC_010582.1 aquaporin 1742302 aqpZ 6217259 aqpZ Streptococcus pneumoniae CGSP14 aquaporin YP_001836473.1 1741634 R 516950 CDS YP_001836474.1 182684727 6216910 complement(1742413..1743210) 1 NC_010582.1 hypothetical protein 1743210 6216910 SPCG_1757 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836474.1 1742413 R 516950 CDS YP_001836475.1 182684728 6216381 complement(1743450..1745246) 1 NC_010582.1 oligoendopeptidase F 1745246 pepF 6216381 pepF Streptococcus pneumoniae CGSP14 oligoendopeptidase F YP_001836475.1 1743450 R 516950 CDS YP_001836476.1 182684729 6217862 complement(1745257..1746012) 1 NC_010582.1 in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA; cells lacking this function can grow, but are outcompeted by wild-type; SAM-dependent m(3)U1498 methyltransferase; 16S ribosomal RNA methyltransferase RsmE 1746012 6217862 SPCG_1759 Streptococcus pneumoniae CGSP14 16S ribosomal RNA methyltransferase RsmE YP_001836476.1 1745257 R 516950 CDS YP_001836477.1 182684730 6217377 complement(1746002..1746952) 1 NC_010582.1 methylates ribosomal protein L11 at multiple amino acid positions; mutations of these genes in Escherichia coli or Thermus thermophilus has no apparent phenotype; 50S ribosomal protein L11 methyltransferase 1746952 prmA 6217377 prmA Streptococcus pneumoniae CGSP14 50S ribosomal protein L11 methyltransferase YP_001836477.1 1746002 R 516950 CDS YP_001836478.1 182684731 6217740 complement(1746965..1747984) 1 NC_010582.1 hypothetical protein 1747984 6217740 SPCG_1761 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836478.1 1746965 R 516950 CDS YP_001836479.1 182684732 6217615 complement(1748035..1750278) 1 NC_010582.1 subtilisin-like serine protease 1750278 6217615 SPCG_1762 Streptococcus pneumoniae CGSP14 subtilisin-like serine protease YP_001836479.1 1748035 R 516950 CDS YP_001836480.1 182684733 6217754 complement(1750280..1751314) 1 NC_010582.1 ATPase AAA 1751314 6217754 SPCG_1763 Streptococcus pneumoniae CGSP14 ATPase AAA YP_001836480.1 1750280 R 516950 CDS YP_001836481.1 182684734 6218583 complement(1751424..1751582) 1 NC_010582.1 mutT/nudix family protein 1751582 6218583 SPCG_1764 Streptococcus pneumoniae CGSP14 mutT/nudix family protein YP_001836481.1 1751424 R 516950 CDS YP_001836482.1 182684735 6218319 complement(1751563..1752666) 1 NC_010582.1 hypothetical protein 1752666 6218319 SPCG_1765 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836482.1 1751563 R 516950 CDS YP_001836483.1 182684736 6217831 complement(1752670..1753140) 1 NC_010582.1 hypothetical protein 1753140 6217831 SPCG_1766 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836483.1 1752670 R 516950 CDS YP_001836484.1 182684737 6217535 complement(1753431..1753883) 1 NC_010582.1 hypothetical protein 1753883 6217535 SPCG_1767 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836484.1 1753431 R 516950 CDS YP_001836485.1 182684738 6218588 complement(1754236..1754415) 1 NC_010582.1 hypothetical protein 1754415 6218588 SPCG_1768 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836485.1 1754236 R 516950 CDS YP_001836486.1 182684739 6218337 complement(1754486..1754590) 1 NC_010582.1 hypothetical protein 1754590 6218337 SPCG_1769 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836486.1 1754486 R 516950 CDS YP_001836487.1 182684740 6216374 complement(1754580..1754822) 1 NC_010582.1 hypothetical protein 1754822 6216374 SPCG_1770 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836487.1 1754580 R 516950 CDS YP_001836488.1 182684741 6217047 1755092..1756363 1 NC_010582.1 recombination factor protein RarA 1756363 6217047 SPCG_1771 Streptococcus pneumoniae CGSP14 recombination factor protein RarA YP_001836488.1 1755092 D 516950 CDS YP_001836489.1 182684742 6217373 complement(1756908..1758233) 1 NC_010582.1 sucrose-6-phosphate hydrolase 1758233 sacA 6217373 sacA Streptococcus pneumoniae CGSP14 sucrose-6-phosphate hydrolase YP_001836489.1 1756908 R 516950 CDS YP_001836490.1 182684743 6216616 complement(1758237..1759949) 1 NC_010582.1 ABC transporter substrate-binding protein 1759949 6216616 SPCG_1773 Streptococcus pneumoniae CGSP14 ABC transporter substrate-binding protein YP_001836490.1 1758237 R 516950 CDS YP_001836491.1 182684744 6218005 complement(1759882..1760799) 1 NC_010582.1 ABC transporter permease 1760799 6218005 SPCG_1774 Streptococcus pneumoniae CGSP14 ABC transporter permease YP_001836491.1 1759882 R 516950 CDS YP_001836492.1 182684745 6217995 complement(1760783..1761727) 1 NC_010582.1 ABC transporter permease 1761727 6217995 SPCG_1775 Streptococcus pneumoniae CGSP14 ABC transporter permease YP_001836492.1 1760783 R 516950 CDS YP_001836493.1 182684746 6217117 complement(1761850..1762869) 1 NC_010582.1 LacI family sugar-binding transcriptional regulator 1762869 6217117 SPCG_1776 Streptococcus pneumoniae CGSP14 LacI family sugar-binding transcriptional regulator YP_001836493.1 1761850 R 516950 CDS YP_001836494.1 182684747 6218160 complement(1763212..1764750) 1 NC_010582.1 transcriptional activator 1764750 6218160 SPCG_1777 Streptococcus pneumoniae CGSP14 transcriptional activator YP_001836494.1 1763212 R 516950 CDS YP_001836495.1 182684748 6217720 1765136..1765300 1 NC_010582.1 hypothetical protein 1765300 6217720 SPCG_1778 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836495.1 1765136 D 516950 CDS YP_001836496.1 182684749 6217101 1765378..1765950 1 NC_010582.1 hypothetical protein 1765950 6217101 SPCG_1779 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836496.1 1765378 D 516950 CDS YP_001836497.1 182684750 6216679 1765962..1766132 1 NC_010582.1 hypothetical protein 1766132 6216679 SPCG_1780 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836497.1 1765962 D 516950 CDS YP_001836498.1 182684751 6218569 1766171..1766779 1 NC_010582.1 general stress protein 24 1766779 6218569 SPCG_1781 Streptococcus pneumoniae CGSP14 general stress protein 24 YP_001836498.1 1766171 D 516950 CDS YP_001836499.1 182684752 6218575 1766810..1767013 1 NC_010582.1 hypothetical protein 1767013 6218575 SPCG_1782 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836499.1 1766810 D 516950 CDS YP_001836500.1 182684753 6218566 complement(1768163..1768933) 1 NC_010582.1 hypothetical protein 1768933 6218566 SPCG_1783 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836500.1 1768163 R 516950 CDS YP_001836501.1 182684754 6216413 complement(1768948..1769796) 1 NC_010582.1 hypothetical protein 1769796 6216413 SPCG_1784 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836501.1 1768948 R 516950 CDS YP_001836502.1 182684755 6218535 complement(1769793..1771268) 1 NC_010582.1 can hydrolyze p-nitrophenyl sulfate; contains a specific cysteine that is converted into C{alpha]-formylglycine upon activation with the anaerobic sulfatase-maturase; arylsulfatase 1771268 6218535 SPCG_1785 Streptococcus pneumoniae CGSP14 arylsulfatase YP_001836502.1 1769793 R 516950 CDS YP_001836503.1 182684756 6216399 complement(1771591..1772946) 1 NC_010582.1 PTS system cellobiose-specific transporter subunit IIC 1772946 6216399 SPCG_1786 Streptococcus pneumoniae CGSP14 PTS system cellobiose-specific transporter subunit IIC YP_001836503.1 1771591 R 516950 CDS YP_001836504.1 182684757 6218541 complement(1772956..1773273) 1 NC_010582.1 PTS system cellobiose-specific transporter subunit IIA 1773273 6218541 SPCG_1787 Streptococcus pneumoniae CGSP14 PTS system cellobiose-specific transporter subunit IIA YP_001836504.1 1772956 R 516950 CDS YP_001836505.1 182684758 6218491 complement(1773290..1773607) 1 NC_010582.1 PTS system transporter subunit IIB 1773607 6218491 SPCG_1788 Streptococcus pneumoniae CGSP14 PTS system transporter subunit IIB YP_001836505.1 1773290 R 516950 CDS YP_001836506.1 182684759 6218486 complement(1773622..1774524) 1 NC_010582.1 PEP phosphonomutase-like protein 1774524 6218486 SPCG_1789 Streptococcus pneumoniae CGSP14 PEP phosphonomutase-like protein YP_001836506.1 1773622 R 516950 CDS YP_001836507.1 182684760 6217785 complement(1774521..1775783) 1 NC_010582.1 phosphotransferase system cellobiose-specific component IIC 1775783 6217785 SPCG_1790 Streptococcus pneumoniae CGSP14 phosphotransferase system cellobiose-specific component IIC YP_001836507.1 1774521 R 516950 CDS YP_001836508.1 182684761 6217421 1776063..1777241 1 NC_010582.1 ROK family protein 1777241 6217421 SPCG_1791 Streptococcus pneumoniae CGSP14 ROK family protein YP_001836508.1 1776063 D 516950 CDS YP_001836509.1 182684762 6217417 complement(1777469..1777915) 1 NC_010582.1 acetyltransferase 1777915 6217417 SPCG_1792 Streptococcus pneumoniae CGSP14 acetyltransferase YP_001836509.1 1777469 R 516950 CDS YP_001836510.1 182684764 6218567 complement(1777931..1778065) 1 NC_010582.1 hypothetical protein 1778065 6218567 SPCG_1793 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836510.1 1777931 R 516950 CDS YP_001836511.1 182684763 6218367 1778039..1778644 1 NC_010582.1 type IV prepilin peptidase 1778644 pilD 6218367 pilD Streptococcus pneumoniae CGSP14 type IV prepilin peptidase YP_001836511.1 1778039 D 516950 CDS YP_001836512.1 182684765 6217385 complement(1778616..1779461) 1 NC_010582.1 catalyzes the formation of indole and glyceraldehyde 3-phosphate from indoleglycerol phosphate in tryptophan biosynthesis; tryptophan synthase subunit alpha 1779461 trpA 6217385 trpA Streptococcus pneumoniae CGSP14 tryptophan synthase subunit alpha YP_001836512.1 1778616 R 516950 CDS YP_001836513.1 182684766 6217257 complement(1779385..1780608) 1 NC_010582.1 catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate; tryptophan synthase subunit beta 1780608 trpB 6217257 trpB Streptococcus pneumoniae CGSP14 tryptophan synthase subunit beta YP_001836513.1 1779385 R 516950 CDS YP_001836514.1 182684767 6217958 complement(1780586..1781215) 1 NC_010582.1 catalyzes the formation of 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate from N-(5-phospho-beta-D-ribosyl)-anthranilate in tryptophan biosynthesis; N-(5'-phosphoribosyl)anthranilate isomerase 1781215 trpF 6217958 trpF Streptococcus pneumoniae CGSP14 N-(5'-phosphoribosyl)anthranilate isomerase YP_001836514.1 1780586 R 516950 CDS YP_001836515.1 182684768 6218293 complement(1781172..1781939) 1 NC_010582.1 involved in tryptophan biosynthesis; amino acid biosynthesis; converts 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate to C(1)-(3-indolyl)-glycerol 3-phosphate and carbon dioxide and water; indole-3-glycerol-phosphate synthase 1781939 trpC 6218293 trpC Streptococcus pneumoniae CGSP14 indole-3-glycerol-phosphate synthase YP_001836515.1 1781172 R 516950 CDS YP_001836516.1 182684769 6218383 complement(1781936..1782940) 1 NC_010582.1 Catalyzes the conversion of N-(5-phospho-D-ribosyl)-anthranilate and diphosphate to anthranilate and 5-phospho-alpha-D-ribose 1-diphosphate; anthranilate phosphoribosyltransferase 1782940 trpD 6218383 trpD Streptococcus pneumoniae CGSP14 anthranilate phosphoribosyltransferase YP_001836516.1 1781936 R 516950 CDS YP_001836517.1 182684770 6218298 complement(1782951..1783517) 1 NC_010582.1 TrpG; with TrpE catalyzes the formation of anthranilate and glutamate from chorismate and glutamine; TrpG provides the glutamine amidotransferase activity; anthranilate synthase component II 1783517 trpG 6218298 trpG Streptococcus pneumoniae CGSP14 anthranilate synthase component II YP_001836517.1 1782951 R 516950 CDS YP_001836518.1 182684771 6217673 complement(1783514..1784977) 1 NC_010582.1 with component II, the glutamine amidotransferase, catalyzes the formation of anthranilate from chorismate and glutamine; anthranilate synthase component I 1784977 trpE 6217673 trpE Streptococcus pneumoniae CGSP14 anthranilate synthase component I YP_001836518.1 1783514 R 516950 CDS YP_001836519.1 182684772 6217126 complement(1785169..1785261) 1 NC_010582.1 hypothetical protein 1785261 6217126 SPCG_1802 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836519.1 1785169 R 516950 CDS YP_001836520.1 182684773 6216722 complement(1785248..1785499) 1 NC_010582.1 hypothetical protein 1785499 6216722 SPCG_1803 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836520.1 1785248 R 516950 CDS YP_001836521.1 182684774 6218470 complement(1786107..1787108) 1 NC_010582.1 LacI family sugar-binding transcriptional regulator 1787108 6218470 SPCG_1804 Streptococcus pneumoniae CGSP14 LacI family sugar-binding transcriptional regulator YP_001836521.1 1786107 R 516950 CDS YP_001836522.1 182684775 6218398 complement(1787679..1788389) 1 NC_010582.1 mgtC/SapB family protein 1788389 6218398 SPCG_1805 Streptococcus pneumoniae CGSP14 mgtC/SapB family protein YP_001836522.1 1787679 R 516950 CDS YP_001836523.1 182684776 6216431 complement(1788392..1789903) 1 NC_010582.1 ABC transporter permease 1789903 6216431 SPCG_1806 Streptococcus pneumoniae CGSP14 ABC transporter permease YP_001836523.1 1788392 R 516950 CDS YP_001836524.1 182684777 6218530 complement(1790094..1791104) 1 NC_010582.1 ABC transporter ATP-binding protein 1791104 6218530 SPCG_1807 Streptococcus pneumoniae CGSP14 ABC transporter ATP-binding protein YP_001836524.1 1790094 R 516950 CDS YP_001836525.1 182684778 6218410 complement(1791207..1792274) 1 NC_010582.1 ABC transporter substrate-binding protein 1792274 6218410 SPCG_1808 Streptococcus pneumoniae CGSP14 ABC transporter substrate-binding protein YP_001836525.1 1791207 R 516950 CDS YP_001836526.1 182684779 6216412 complement(1792299..1792958) 1 NC_010582.1 hypothetical protein 1792958 6216412 SPCG_1809 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836526.1 1792299 R 516950 CDS YP_001836527.1 182684780 6217815 complement(1793687..1793983) 1 NC_010582.1 hypothetical protein 1793983 6217815 SPCG_1810 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836527.1 1793687 R 516950 CDS YP_001836528.1 182684781 6217338 complement(1793967..1796126) 1 NC_010582.1 cell wall surface anchor family protein 1796126 6217338 SPCG_1811 Streptococcus pneumoniae CGSP14 cell wall surface anchor family protein YP_001836528.1 1793967 R 516950 CDS YP_001836529.1 182684782 6217285 complement(1797256..1798509) 1 NC_010582.1 capsular polysaccharide biosynthesis protein 1798509 6217285 SPCG_1812 Streptococcus pneumoniae CGSP14 capsular polysaccharide biosynthesis protein YP_001836529.1 1797256 R 516950 CDS YP_001836530.1 182684783 6218024 complement(1798525..1799256) 1 NC_010582.1 glycosyl transferase family protein 1799256 6218024 SPCG_1813 Streptococcus pneumoniae CGSP14 glycosyl transferase family protein YP_001836530.1 1798525 R 516950 CDS YP_001836531.1 182684784 6217290 complement(1799390..1801141) 1 NC_010582.1 ABC transporter ATP-binding protein/permease 1801141 6217290 SPCG_1814 Streptococcus pneumoniae CGSP14 ABC transporter ATP-binding protein/permease YP_001836531.1 1799390 R 516950 CDS YP_001836532.1 182684785 6217802 complement(1801131..1802915) 1 NC_010582.1 ABC transporter ATP-binding protein/permease 1802915 6217802 SPCG_1815 Streptococcus pneumoniae CGSP14 ABC transporter ATP-binding protein/permease YP_001836532.1 1801131 R 516950 CDS YP_001836533.1 182684786 6218480 complement(1803004..1803534) 1 NC_010582.1 hypothetical protein 1803534 6218480 SPCG_1816 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836533.1 1803004 R 516950 CDS YP_001836534.1 182684787 6217370 complement(1803531..1803800) 1 NC_010582.1 hypothetical protein 1803800 6217370 SPCG_1817 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836534.1 1803531 R 516950 CDS YP_001836535.1 182684788 6216939 1804120..1804947 1 NC_010582.1 exodeoxyribonuclease 1804947 exoA 6216939 exoA Streptococcus pneumoniae CGSP14 exodeoxyribonuclease YP_001836535.1 1804120 D 516950 CDS YP_001836536.1 182684789 6217882 1805102..1805206 1 NC_010582.1 hypothetical protein 1805206 6217882 SPCG_1819 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836536.1 1805102 D 516950 CDS YP_001836537.1 182684790 6216683 1805210..1805341 1 NC_010582.1 hypothetical protein 1805341 6216683 SPCG_1820 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836537.1 1805210 D 516950 CDS YP_001836538.1 182684791 6218023 1806219..1806800 1 NC_010582.1 Catalyzes the transfer of the phosphoribosyl moiety from 5-phospho--D-ribosyl-1-pyrophosphate (PRib-PP) to the 6-oxo-guanine and -xanthine; xanthine phosphoribosyltransferase 1806800 xpt 6218023 xpt Streptococcus pneumoniae CGSP14 xanthine phosphoribosyltransferase YP_001836538.1 1806219 D 516950 CDS YP_001836539.1 182684792 6216594 1806800..1808062 1 NC_010582.1 xanthine permease 1808062 6216594 SPCG_1822 Streptococcus pneumoniae CGSP14 xanthine permease YP_001836539.1 1806800 D 516950 CDS YP_001836540.1 182684793 6217320 complement(1808113..1808574) 1 NC_010582.1 dpnD protein 1808574 dpnD 6217320 dpnD Streptococcus pneumoniae CGSP14 dpnD protein YP_001836540.1 1808113 R 516950 CDS YP_001836541.1 182684794 6218551 complement(1808571..1809335) 1 NC_010582.1 type II restriction endonuclease DpnI 1809335 dpnC 6218551 dpnC Streptococcus pneumoniae CGSP14 type II restriction endonuclease DpnI YP_001836541.1 1808571 R 516950 CDS YP_001836542.1 182684795 6217404 complement(1809577..1809957) 1 NC_010582.1 hypothetical protein 1809957 6217404 SPCG_1825 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836542.1 1809577 R 516950 CDS YP_001836543.1 182684796 6217075 complement(1810006..1811487) 1 NC_010582.1 catalyzes the formation of alpha-D-glucose 1-phosphate and UDP-galactose from UDP-glucose and alpha-D-galactose 1-phosphate in galactose metabolism; galactose-1-phosphate uridylyltransferase 1811487 galT 6217075 galT Streptococcus pneumoniae CGSP14 galactose-1-phosphate uridylyltransferase YP_001836543.1 1810006 R 516950 CDS YP_001836544.1 182684797 6217626 complement(1811506..1812684) 1 NC_010582.1 catalyzes the formation of alpha-D-galactose 1-phosphate from D-galactose in galactose metabolism; galactokinase 1812684 galK 6217626 galK Streptococcus pneumoniae CGSP14 galactokinase YP_001836544.1 1811506 R 516950 CDS YP_001836545.1 182684798 6216615 1812848..1813855 1 NC_010582.1 galactose operon repressor 1813855 galR 6216615 galR Streptococcus pneumoniae CGSP14 galactose operon repressor YP_001836545.1 1812848 D 516950 CDS YP_001836546.1 182684799 6217474 complement(1813901..1814938) 1 NC_010582.1 zinc-containing alcohol dehydrogenase 1814938 adhB 6217474 adhB Streptococcus pneumoniae CGSP14 zinc-containing alcohol dehydrogenase YP_001836546.1 1813901 R 516950 CDS YP_001836547.1 182684800 6216825 complement(1814939..1815292) 1 NC_010582.1 MerR family transcriptional regulator 1815292 6216825 SPCG_1830 Streptococcus pneumoniae CGSP14 MerR family transcriptional regulator YP_001836547.1 1814939 R 516950 CDS YP_001836548.1 182684801 6217446 complement(1815536..1816435) 1 NC_010582.1 cation efflux system protein 1816435 6217446 SPCG_1831 Streptococcus pneumoniae CGSP14 cation efflux system protein YP_001836548.1 1815536 R 516950 CDS YP_001836549.1 182684802 6218543 1816559..1817095 1 NC_010582.1 TetR family transcriptional regulator 1817095 6218543 SPCG_1832 Streptococcus pneumoniae CGSP14 TetR family transcriptional regulator YP_001836549.1 1816559 D 516950 CDS YP_001836550.1 182684803 6217869 complement(1817261..1818070) 1 NC_010582.1 transporter 1818070 6217869 SPCG_1833 Streptococcus pneumoniae CGSP14 transporter YP_001836550.1 1817261 R 516950 CDS YP_001836551.1 182684804 6217138 complement(1818411..1819946) 1 NC_010582.1 choline transporter 1819946 6217138 SPCG_1834 Streptococcus pneumoniae CGSP14 choline transporter YP_001836551.1 1818411 R 516950 CDS YP_001836552.1 182684805 6218328 complement(1819924..1820652) 1 NC_010582.1 choline transporter 1820652 6218328 SPCG_1835 Streptococcus pneumoniae CGSP14 choline transporter YP_001836552.1 1819924 R 516950 CDS YP_001836553.1 182684806 6217877 complement(1820667..1821431) 1 NC_010582.1 hypothetical protein 1821431 6217877 SPCG_1836 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836553.1 1820667 R 516950 CDS YP_001836554.1 182684807 6218125 complement(1821435..1821878) 1 NC_010582.1 MarR family transcriptional regulator 1821878 6218125 SPCG_1837 Streptococcus pneumoniae CGSP14 MarR family transcriptional regulator YP_001836554.1 1821435 R 516950 CDS YP_001836555.1 182684808 6217735 complement(1822560..1822865) 1 NC_010582.1 hypothetical protein 1822865 6217735 SPCG_1838 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836555.1 1822560 R 516950 CDS YP_001836556.1 182684809 6217871 complement(1822878..1823942) 1 NC_010582.1 glutamyl-aminopeptidase 1823942 pepA 6217871 pepA Streptococcus pneumoniae CGSP14 glutamyl-aminopeptidase YP_001836556.1 1822878 R 516950 CDS YP_001836557.1 182684810 6216972 1824343..1825044 1 NC_010582.1 NAD-dependent epimerase/dehydratase family protein 1825044 6216972 SPCG_1840 Streptococcus pneumoniae CGSP14 NAD-dependent epimerase/dehydratase family protein YP_001836557.1 1824343 D 516950 CDS YP_001836558.1 182684811 6217201 1825060..1825170 1 NC_010582.1 hypothetical protein 1825170 6217201 SPCG_1841 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836558.1 1825060 D 516950 CDS YP_001836559.1 182684812 6216493 1825452..1826426 1 NC_010582.1 iron-compound ABC transporter permease 1826426 6216493 SPCG_1842 Streptococcus pneumoniae CGSP14 iron-compound ABC transporter permease YP_001836559.1 1825452 D 516950 CDS YP_001836560.1 182684813 6216495 1826416..1827372 1 NC_010582.1 iron-compound ABC transporter permease 1827372 6216495 SPCG_1843 Streptococcus pneumoniae CGSP14 iron-compound ABC transporter permease YP_001836560.1 1826416 D 516950 CDS YP_001836561.1 182684814 6216896 1827369..1828121 1 NC_010582.1 iron-compound ABC transporter ATP-binding protein 1828121 6216896 SPCG_1844 Streptococcus pneumoniae CGSP14 iron-compound ABC transporter ATP-binding protein YP_001836561.1 1827369 D 516950 CDS YP_001836562.1 182684815 6217012 1828217..1829182 1 NC_010582.1 iron-compound ABC transporter iron-compound-binding protein 1829182 6217012 SPCG_1845 Streptococcus pneumoniae CGSP14 iron-compound ABC transporter iron-compound-binding protein YP_001836562.1 1828217 D 516950 CDS YP_001836563.1 182684816 6217692 complement(1829407..1829649) 1 NC_010582.1 hypothetical protein 1829649 6217692 SPCG_1846 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836563.1 1829407 R 516950 CDS YP_001836564.1 182684817 6216481 complement(1829649..1830371) 1 NC_010582.1 ribosomal large subunit pseudouridine synthase B 1830371 rluB 6216481 rluB Streptococcus pneumoniae CGSP14 ribosomal large subunit pseudouridine synthase B YP_001836564.1 1829649 R 516950 CDS YP_001836565.1 182684818 6216628 complement(1830358..1830927) 1 NC_010582.1 functions during chromosome segregation; may form a condensin-like structure with SMC and ScpA; forms a homodimer; segregation and condensation protein B 1830927 scpB 6216628 scpB Streptococcus pneumoniae CGSP14 segregation and condensation protein B YP_001836565.1 1830358 R 516950 CDS YP_001836566.1 182684819 6217341 complement(1830946..1831674) 1 NC_010582.1 functions during chromosome segregation; may form a condensin-like structure with SMC and ScpB; segregation and condensation protein A 1831674 scpA 6217341 scpA Streptococcus pneumoniae CGSP14 segregation and condensation protein A YP_001836566.1 1830946 R 516950 CDS YP_001836567.1 182684820 6217094 complement(1831674..1832414) 1 NC_010582.1 site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs; site-specific tyrosine recombinase XerD 1832414 xerD 6217094 xerD Streptococcus pneumoniae CGSP14 site-specific tyrosine recombinase XerD YP_001836567.1 1831674 R 516950 CDS YP_001836568.1 182684821 6217211 complement(1832405..1832866) 1 NC_010582.1 hypothetical protein 1832866 6217211 SPCG_1851 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836568.1 1832405 R 516950 CDS YP_001836569.1 182684822 6217424 complement(1832863..1833384) 1 NC_010582.1 hypothetical protein 1833384 6217424 SPCG_1852 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836569.1 1832863 R 516950 CDS YP_001836570.1 182684823 6216923 complement(1833360..1834370) 1 NC_010582.1 HAM1-like protein; Rec-dependent growth; RgdB; yggV; it is suspected that this protein functions to remove misincorporated bases such as xanthine or hypoxanthine; deoxyribonucleotide triphosphate pyrophosphatase/unknown domain fusion protein 1834370 6216923 SPCG_1853 Streptococcus pneumoniae CGSP14 deoxyribonucleotide triphosphate pyrophosphatase/unknown domain fusion protein YP_001836570.1 1833360 R 516950 CDS YP_001836571.1 182684824 6217330 complement(1834328..1835122) 1 NC_010582.1 converts L-glutamate to D-glutamate, a component of peptidoglycan; glutamate racemase 1835122 murI 6217330 murI Streptococcus pneumoniae CGSP14 glutamate racemase YP_001836571.1 1834328 R 516950 CDS YP_001836572.1 182684825 6217771 complement(1835329..1835631) 1 NC_010582.1 hypothetical protein 1835631 6217771 SPCG_1855 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836572.1 1835329 R 516950 CDS YP_001836573.1 182684826 6216967 complement(1835833..1837458) 1 NC_010582.1 dextran glucosidase DexS 1837458 dexS 6216967 dexS Streptococcus pneumoniae CGSP14 dextran glucosidase DexS YP_001836573.1 1835833 R 516950 CDS YP_001836574.1 182684827 6217099 complement(1837636..1839753) 1 NC_010582.1 trehalose PTS system, IIABC components 1839753 treP 6217099 treP Streptococcus pneumoniae CGSP14 trehalose PTS system, IIABC components YP_001836574.1 1837636 R 516950 CDS YP_001836575.1 182684828 6218406 1839788..1840498 1 NC_010582.1 trehalose operon transcriptional repressor 1840498 treR 6218406 treR Streptococcus pneumoniae CGSP14 trehalose operon transcriptional repressor YP_001836575.1 1839788 D 516950 CDS YP_001836576.1 182684829 6217166 1840653..1841171 1 NC_010582.1 degenerate transposase 1841171 6217166 SPCG_1859 Streptococcus pneumoniae CGSP14 degenerate transposase YP_001836576.1 1840653 D 516950 CDS YP_001836577.1 182684830 6218283 1841452..1841979 1 NC_010582.1 degenerate transposase 1841979 6218283 SPCG_1860 Streptococcus pneumoniae CGSP14 degenerate transposase YP_001836577.1 1841452 D 516950 CDS YP_001836578.1 182684831 6216387 complement(1842054..1843049) 1 NC_010582.1 oligopeptide ABC transporter ATP-binding protein AmiF 1843049 amiF 6216387 amiF Streptococcus pneumoniae CGSP14 oligopeptide ABC transporter ATP-binding protein AmiF YP_001836578.1 1842054 R 516950 CDS YP_001836579.1 182684832 6216416 complement(1842991..1844058) 1 NC_010582.1 oligopeptide ABC transporter ATP-binding protein AmiE 1844058 amiE 6216416 amiE Streptococcus pneumoniae CGSP14 oligopeptide ABC transporter ATP-binding protein AmiE YP_001836579.1 1842991 R 516950 CDS YP_001836580.1 182684833 6216948 complement(1844067..1844993) 1 NC_010582.1 oligopeptide ABC transporter permease AmiD 1844993 amiD 6216948 amiD Streptococcus pneumoniae CGSP14 oligopeptide ABC transporter permease AmiD YP_001836580.1 1844067 R 516950 CDS YP_001836581.1 182684834 6217816 complement(1844993..1846489) 1 NC_010582.1 oligopeptide ABC transporter permease AmiC 1846489 amiC 6217816 amiC Streptococcus pneumoniae CGSP14 oligopeptide ABC transporter permease AmiC YP_001836581.1 1844993 R 516950 CDS YP_001836582.1 182684835 6217593 complement(1846556..1848535) 1 NC_010582.1 oligopeptide ABC transporter oligopeptide-binding protein AmiA 1848535 amiA 6217593 amiA Streptococcus pneumoniae CGSP14 oligopeptide ABC transporter oligopeptide-binding protein AmiA YP_001836582.1 1846556 R 516950 CDS YP_001836583.1 182684836 6216595 complement(1849221..1850414) 1 NC_010582.1 hypothetical protein 1850414 6216595 SPCG_1866 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836583.1 1849221 R 516950 CDS YP_001836584.1 182684837 6218512 complement(1850552..1852024) 1 NC_010582.1 sucrose phosphorylase 1852024 6218512 SPCG_1867 Streptococcus pneumoniae CGSP14 sucrose phosphorylase YP_001836584.1 1850552 R 516950 CDS YP_001836585.1 182684838 6217795 complement(1852205..1852345) 1 NC_010582.1 hypothetical protein 1852345 6217795 SPCG_1868 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836585.1 1852205 R 516950 CDS YP_001836586.1 182684839 6218468 complement(1852352..1853209) 1 NC_010582.1 sugar ABC transporter permease 1853209 6218468 SPCG_1869 Streptococcus pneumoniae CGSP14 sugar ABC transporter permease YP_001836586.1 1852352 R 516950 CDS YP_001836587.1 182684840 6218501 complement(1853199..1854089) 1 NC_010582.1 sugar ABC transporter permease 1854089 6218501 SPCG_1870 Streptococcus pneumoniae CGSP14 sugar ABC transporter permease YP_001836587.1 1853199 R 516950 CDS YP_001836588.1 182684841 6218534 complement(1854079..1855338) 1 NC_010582.1 sugar ABC transporter sugar-binding protein 1855338 6218534 SPCG_1871 Streptococcus pneumoniae CGSP14 sugar ABC transporter sugar-binding protein YP_001836588.1 1854079 R 516950 CDS YP_001836589.1 182684842 6218387 complement(1855373..1857535) 1 NC_010582.1 alpha-galactosidase 1857535 aga 6218387 aga Streptococcus pneumoniae CGSP14 alpha-galactosidase YP_001836589.1 1855373 R 516950 CDS YP_001836590.1 182684843 6218165 1857643..1858503 1 NC_010582.1 msm operon regulatory protein 1858503 msmR 6218165 msmR Streptococcus pneumoniae CGSP14 msm operon regulatory protein YP_001836590.1 1857643 D 516950 CDS YP_001836591.1 182684844 6217950 1858500..1859435 1 NC_010582.1 catalyzes the formation of biotinyl-5'-AMP, also acts as a transcriptional repressor of the biotin operon; biotin--protein ligase 1859435 birA 6217950 birA Streptococcus pneumoniae CGSP14 biotin--protein ligase YP_001836591.1 1858500 D 516950 CDS YP_001836592.1 182684846 6217730 complement(1866338..1867693) 1 NC_010582.1 RNA methyltransferase 1867693 6217730 SPCG_1875 Streptococcus pneumoniae CGSP14 RNA methyltransferase YP_001836592.1 1866338 R 516950 CDS YP_001836593.1 182684845 6218371 1867663..1868526 1 NC_010582.1 aminoglycoside phosphotransferase 1868526 6218371 SPCG_1876 Streptococcus pneumoniae CGSP14 aminoglycoside phosphotransferase YP_001836593.1 1867663 D 516950 CDS YP_001836594.1 182684847 6217857 1868536..1869312 1 NC_010582.1 binds RecA and inhibits RecA-mediated DNA strand exchange and ATP hydrolysis and coprotease activities; recombination regulator RecX 1869312 recX 6217857 recX Streptococcus pneumoniae CGSP14 recombination regulator RecX YP_001836594.1 1868536 D 516950 CDS YP_001836595.1 182684848 6216563 1869401..1869934 1 NC_010582.1 hypothetical protein 1869934 6216563 SPCG_1878 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836595.1 1869401 D 516950 CDS YP_001836596.1 182684849 6217641 complement(1870291..1870497) 1 NC_010582.1 hypothetical protein 1870497 6217641 SPCG_1879 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836596.1 1870291 R 516950 CDS YP_001836597.1 182684850 6217059 1870657..1871886 1 NC_010582.1 IS1167, transposase 1871886 6217059 SPCG_1880 Streptococcus pneumoniae CGSP14 IS1167, transposase YP_001836597.1 1870657 D 516950 CDS YP_001836598.1 182684851 6217433 complement(1871986..1873608) 1 NC_010582.1 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth; chaperonin GroEL 1873608 groEL 6217433 groEL Streptococcus pneumoniae CGSP14 chaperonin GroEL YP_001836598.1 1871986 R 516950 CDS YP_001836599.1 182684852 6217284 complement(1873624..1873908) 1 NC_010582.1 10 kDa chaperonin; Cpn10; GroES; forms homoheptameric ring; binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it; folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES; release of the folded substrate is dependent on ATP binding and hydrolysis in the trans ring; co-chaperonin GroES 1873908 groES 6217284 groES Streptococcus pneumoniae CGSP14 co-chaperonin GroES YP_001836599.1 1873624 R 516950 CDS YP_001836600.1 182684853 6216947 complement(1874178..1874573) 1 NC_010582.1 binds to single stranded DNA and may facilitate the binding and interaction of other proteins to DNA; single-stranded DNA-binding protein 1874573 ssbB 6216947 ssbB Streptococcus pneumoniae CGSP14 single-stranded DNA-binding protein YP_001836600.1 1874178 R 516950 CDS YP_001836601.1 182684854 6217093 complement(1874650..1875411) 1 NC_010582.1 short chain dehydrogenase/reductase family oxidoreductase 1875411 ydfG 6217093 ydfG Streptococcus pneumoniae CGSP14 short chain dehydrogenase/reductase family oxidoreductase YP_001836601.1 1874650 R 516950 CDS YP_001836602.1 182684855 6216743 complement(1875444..1876070) 1 NC_010582.1 hypothetical protein 1876070 6216743 SPCG_1885 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836602.1 1875444 R 516950 CDS YP_001836603.1 182684856 6216492 complement(1876086..1876403) 1 NC_010582.1 thioredoxin 1876403 6216492 SPCG_1886 Streptococcus pneumoniae CGSP14 thioredoxin YP_001836603.1 1876086 R 516950 CDS YP_001836604.1 182684857 6217788 complement(1876400..1876699) 1 NC_010582.1 hypothetical protein 1876699 6217788 SPCG_1887 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836604.1 1876400 R 516950 CDS YP_001836605.1 182684858 6216694 complement(1877036..1877251) 1 NC_010582.1 hypothetical protein 1877251 6216694 SPCG_1888 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836605.1 1877036 R 516950 CDS YP_001836606.1 182684859 6217566 complement(1877388..1878062) 1 NC_010582.1 hypothetical protein 1878062 6217566 SPCG_1889 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836606.1 1877388 R 516950 CDS YP_001836607.1 182684860 6217722 complement(1878068..1878517) 1 NC_010582.1 hypothetical protein 1878517 6217722 SPCG_1890 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836607.1 1878068 R 516950 CDS YP_001836608.1 182684861 6216390 complement(1878628..1879131) 1 NC_010582.1 PAP2 family protein 1879131 6216390 SPCG_1891 Streptococcus pneumoniae CGSP14 PAP2 family protein YP_001836608.1 1878628 R 516950 CDS YP_001836609.1 182684862 6217790 complement(1879128..1879490) 1 NC_010582.1 hypothetical protein 1879490 6217790 SPCG_1892 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836609.1 1879128 R 516950 CDS YP_001836610.1 182684863 6218052 complement(1879556..1880587) 1 NC_010582.1 ABC transporter ATP-binding protein 1880587 6218052 SPCG_1893 Streptococcus pneumoniae CGSP14 ABC transporter ATP-binding protein YP_001836610.1 1879556 R 516950 CDS YP_001836611.1 182684864 6217142 complement(1880594..1881415) 1 NC_010582.1 ABC transporter permease 1881415 6217142 SPCG_1894 Streptococcus pneumoniae CGSP14 ABC transporter permease YP_001836611.1 1880594 R 516950 CDS YP_001836612.1 182684865 6216477 complement(1881432..1881548) 1 NC_010582.1 hypothetical protein 1881548 6216477 SPCG_1895 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836612.1 1881432 R 516950 CDS YP_001836613.1 182684866 6217388 complement(1881557..1881901) 1 NC_010582.1 MarR family transcriptional regulator 1881901 6217388 SPCG_1896 Streptococcus pneumoniae CGSP14 MarR family transcriptional regulator YP_001836613.1 1881557 R 516950 CDS YP_001836614.1 182684867 6217183 complement(1882025..1882741) 1 NC_010582.1 hypothetical protein 1882741 6217183 SPCG_1897 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836614.1 1882025 R 516950 CDS YP_001836615.1 182684868 6217360 complement(1883622..1885037) 1 NC_010582.1 pneumolysin 1885037 ply 6217360 ply Streptococcus pneumoniae CGSP14 pneumolysin YP_001836615.1 1883622 R 516950 CDS YP_001836616.1 182684869 6216542 complement(1885048..1885458) 1 NC_010582.1 hypothetical protein 1885458 6216542 SPCG_1899 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836616.1 1885048 R 516950 CDS YP_001836617.1 182684870 6217538 complement(1885451..1886059) 1 NC_010582.1 hypothetical protein 1886059 6217538 SPCG_1900 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836617.1 1885451 R 516950 CDS YP_001836618.1 182684871 6217759 complement(1886072..1886548) 1 NC_010582.1 hypothetical protein 1886548 6217759 SPCG_1901 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836618.1 1886072 R 516950 CDS YP_001836619.1 182684872 6218288 1886655..1886786 1 NC_010582.1 degenerate transposase 1886786 6218288 SPCG_1902 Streptococcus pneumoniae CGSP14 degenerate transposase YP_001836619.1 1886655 D 516950 CDS YP_001836620.1 182684873 6218171 1886791..1887054 1 NC_010582.1 degenerate transposase 1887054 6218171 SPCG_1903 Streptococcus pneumoniae CGSP14 degenerate transposase YP_001836620.1 1886791 D 516950 CDS YP_001836621.1 182684874 6218242 complement(1887819..1888079) 1 NC_010582.1 hypothetical protein 1888079 6218242 SPCG_1904 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836621.1 1887819 R 516950 CDS YP_001836622.1 182684875 6216515 complement(1888138..1888692) 1 NC_010582.1 hypothetical protein 1888692 6216515 SPCG_1905 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836622.1 1888138 R 516950 CDS YP_001836623.1 182684876 6217228 complement(1888679..1888777) 1 NC_010582.1 hypothetical protein 1888777 6217228 SPCG_1906 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836623.1 1888679 R 516950 CDS YP_001836624.1 182684877 6218034 complement(1888839..1888937) 1 NC_010582.1 hypothetical protein 1888937 6218034 SPCG_1907 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836624.1 1888839 R 516950 CDS YP_001836625.1 182684878 6216827 complement(1888880..1889464) 1 NC_010582.1 hypothetical protein 1889464 6216827 SPCG_1908 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836625.1 1888880 R 516950 CDS YP_001836626.1 182684879 6217677 complement(1889872..1890297) 1 NC_010582.1 hypothetical protein 1890297 6217677 SPCG_1909 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836626.1 1889872 R 516950 CDS YP_001836627.1 182684880 6216625 complement(1890426..1890785) 1 NC_010582.1 hypothetical protein 1890785 6216625 SPCG_1910 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836627.1 1890426 R 516950 CDS YP_001836628.1 182684881 6216949 complement(1891024..1891185) 1 NC_010582.1 type II restriction-modification system regulatory protein 1891185 6216949 SPCG_1965 Streptococcus pneumoniae CGSP14 type II restriction-modification system regulatory protein YP_001836628.1 1891024 R 516950 CDS YP_001836629.1 182684882 6217991 complement(1891531..1892487) 1 NC_010582.1 autolysin 1892487 lytA 6217991 lytA Streptococcus pneumoniae CGSP14 autolysin YP_001836629.1 1891531 R 516950 CDS YP_001836630.1 182684883 6216772 complement(1892863..1894233) 1 NC_010582.1 MATE efflux family protein DinF 1894233 dinF 6216772 dinF Streptococcus pneumoniae CGSP14 MATE efflux family protein DinF YP_001836630.1 1892863 R 516950 CDS YP_001836631.1 182684884 6216804 complement(1894540..1895706) 1 NC_010582.1 catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs; recombinase A 1895706 recA 6216804 recA Streptococcus pneumoniae CGSP14 recombinase A YP_001836631.1 1894540 R 516950 CDS YP_001836632.1 182684885 6217299 complement(1895761..1897017) 1 NC_010582.1 competence damage-inducible protein A 1897017 cinA 6217299 cinA Streptococcus pneumoniae CGSP14 competence damage-inducible protein A YP_001836632.1 1895761 R 516950 CDS YP_001836633.1 182684886 6217394 complement(1897102..1898118) 1 NC_010582.1 transcriptional regulator 1898118 lytR 6217394 lytR Streptococcus pneumoniae CGSP14 transcriptional regulator YP_001836633.1 1897102 R 516950 CDS YP_001836634.1 182684887 6217886 complement(1898126..1898644) 1 NC_010582.1 acetyltransferase 1898644 6217886 SPCG_1916 Streptococcus pneumoniae CGSP14 acetyltransferase YP_001836634.1 1898126 R 516950 CDS YP_001836635.1 182684888 6218115 complement(1898634..1899077) 1 NC_010582.1 hypothetical protein 1899077 6218115 SPCG_1917 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836635.1 1898634 R 516950 CDS YP_001836636.1 182684889 6216757 complement(1899163..1899804) 1 NC_010582.1 hypothetical protein 1899804 6216757 SPCG_1918 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836636.1 1899163 R 516950 CDS YP_001836637.1 182684890 6216844 complement(1900165..1901028) 1 NC_010582.1 transcriptional regulator PlcR 1901028 plcR 6216844 plcR Streptococcus pneumoniae CGSP14 transcriptional regulator PlcR YP_001836637.1 1900165 R 516950 CDS YP_001836638.1 182684891 6218015 1901217..1901387 1 NC_010582.1 hypothetical protein 1901387 6218015 SPCG_1920 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836638.1 1901217 D 516950 CDS YP_001836639.1 182684892 6217970 1901837..1903852 1 NC_010582.1 hypothetical protein 1903852 6217970 SPCG_1921 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836639.1 1901837 D 516950 CDS YP_001836640.1 182684893 6218148 1903854..1904486 1 NC_010582.1 ABC transporter ATP-binding protein 1904486 6218148 SPCG_1922 Streptococcus pneumoniae CGSP14 ABC transporter ATP-binding protein YP_001836640.1 1903854 D 516950 CDS YP_001836641.1 182684894 6216863 complement(1905432..1905845) 1 NC_010582.1 catalyzes the formation of nucleoside triphosphate from ATP and nucleoside diphosphate; nucleoside diphosphate kinase 1905845 ndk 6216863 ndk Streptococcus pneumoniae CGSP14 nucleoside diphosphate kinase YP_001836641.1 1905432 R 516950 CDS YP_001836642.1 182684895 6218086 complement(1905956..1909633) 1 NC_010582.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Subunit beta' binds to sigma factor allowing it to bind to the -10 region of the promoter; DNA-directed RNA polymerase subunit beta' 1909633 rpoC 6218086 rpoC Streptococcus pneumoniae CGSP14 DNA-directed RNA polymerase subunit beta' YP_001836642.1 1905956 R 516950 CDS YP_001836643.1 182684896 6217608 complement(1909666..1912140) 1 NC_010582.1 hypothetical protein 1912140 6217608 SPCG_1925 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836643.1 1909666 R 516950 CDS YP_001836644.1 182684897 6216737 complement(1912182..1913315) 1 NC_010582.1 hypothetical protein 1913315 6216737 SPCG_1926 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836644.1 1912182 R 516950 CDS YP_001836645.1 182684898 6216579 1913732..1913839 1 NC_010582.1 hypothetical protein 1913839 6216579 SPCG_1927 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836645.1 1913732 D 516950 CDS YP_001836646.1 182684899 6218229 complement(1913960..1915291) 1 NC_010582.1 hypothetical protein 1915291 6218229 SPCG_1928 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836646.1 1913960 R 516950 CDS YP_001836647.1 182684900 6217192 complement(1915582..1916406) 1 NC_010582.1 DNA-entry nuclease 1916406 endA 6217192 endA Streptococcus pneumoniae CGSP14 DNA-entry nuclease YP_001836647.1 1915582 R 516950 CDS YP_001836648.1 182684901 6217527 complement(1916626..1917909) 1 NC_010582.1 adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active; UDP-N-acetylglucosamine 1-carboxyvinyltransferase 1917909 murA 6217527 murA Streptococcus pneumoniae CGSP14 UDP-N-acetylglucosamine 1-carboxyvinyltransferase YP_001836648.1 1916626 R 516950 CDS YP_001836649.1 182684902 6217401 complement(1918221..1919258) 1 NC_010582.1 hypothetical protein 1919258 6217401 SPCG_1931 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836649.1 1918221 R 516950 CDS YP_001836650.1 182684903 6216503 complement(1919242..1919730) 1 NC_010582.1 Catalyzes the conversion of ATP and pantetheine 4'-phosphate to diphosphate and 3'-dephospho-coA; phosphopantetheine adenylyltransferase 1919730 coaD 6216503 coaD Streptococcus pneumoniae CGSP14 phosphopantetheine adenylyltransferase YP_001836650.1 1919242 R 516950 CDS YP_001836651.1 182684904 6217800 complement(1919720..1920259) 1 NC_010582.1 type II DNA modification methyltransferase 1920259 6217800 SPCG_1933 Streptococcus pneumoniae CGSP14 type II DNA modification methyltransferase YP_001836651.1 1919720 R 516950 CDS YP_001836652.1 182684906 6216841 complement(1920324..1921316) 1 NC_010582.1 catalyzes the formation of asparagine from aspartate and ammonia; asparagine synthetase AsnA 1921316 asnA 6216841 asnA Streptococcus pneumoniae CGSP14 asparagine synthetase AsnA YP_001836652.1 1920324 R 516950 CDS YP_001836653.1 182684905 6217153 1921290..1921454 1 NC_010582.1 hypothetical protein 1921454 6217153 SPCG_1935 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836653.1 1921290 D 516950 CDS YP_001836654.1 182684907 6217372 complement(1921428..1922135) 1 NC_010582.1 membrane protein 1922135 6217372 SPCG_1936 Streptococcus pneumoniae CGSP14 membrane protein YP_001836654.1 1921428 R 516950 CDS YP_001836655.1 182684908 6217280 complement(1922167..1922925) 1 NC_010582.1 spoU rRNA methylase family protein 1922925 6217280 SPCG_1937 Streptococcus pneumoniae CGSP14 spoU rRNA methylase family protein YP_001836655.1 1922167 R 516950 CDS YP_001836656.1 182684909 6216460 1922941..1923219 1 NC_010582.1 catalyzes the hydrolysis of acylphosphate; acylphosphatase 1923219 acyP 6216460 acyP Streptococcus pneumoniae CGSP14 acylphosphatase YP_001836656.1 1922941 D 516950 CDS YP_001836657.1 182684910 6218064 1923297..1924223 1 NC_010582.1 involved in biogenesis of membrane proteins; Firmicutes specific proteins are shorter than other bacterial counterparts and have a signal peptide and lipid attachment site; OxaA-like protein precursor 1924223 6218064 SPCG_1939 Streptococcus pneumoniae CGSP14 OxaA-like protein precursor YP_001836657.1 1923297 D 516950 CDS YP_001836658.1 182684911 6217824 complement(1924298..1925092) 1 NC_010582.1 pyruvate formate-lyase-activating enzyme 1925092 pflC 6217824 pflC Streptococcus pneumoniae CGSP14 pyruvate formate-lyase-activating enzyme YP_001836658.1 1924298 R 516950 CDS YP_001836659.1 182684912 6217383 complement(1925218..1926468) 1 NC_010582.1 diaminopimelate decarboxylase 1926468 lysA 6217383 lysA Streptococcus pneumoniae CGSP14 diaminopimelate decarboxylase YP_001836659.1 1925218 R 516950 CDS YP_001836660.1 182684913 6218571 complement(1926535..1927362) 1 NC_010582.1 pur operon repressor 1927362 purR 6218571 purR Streptococcus pneumoniae CGSP14 pur operon repressor YP_001836660.1 1926535 R 516950 CDS YP_001836661.1 182684914 6216488 complement(1927629..1928633) 1 NC_010582.1 cmp-binding-factor 1 1928633 cbf1 6216488 cbf1 Streptococcus pneumoniae CGSP14 cmp-binding-factor 1 YP_001836661.1 1927629 R 516950 CDS YP_001836662.1 182684915 6216462 complement(1928560..1929858) 1 NC_010582.1 competence-induced protein Ccs50 1929858 6216462 SPCG_1944 Streptococcus pneumoniae CGSP14 competence-induced protein Ccs50 YP_001836662.1 1928560 R 516950 CDS YP_001836663.1 182684916 6216518 complement(1929818..1930501) 1 NC_010582.1 hypothetical protein 1930501 6216518 SPCG_1945 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836663.1 1929818 R 516950 CDS YP_001836664.1 182684917 6217356 complement(1930443..1931162) 1 NC_010582.1 ribulose-phosphate 3-epimerase 1931162 rpe 6217356 rpe Streptococcus pneumoniae CGSP14 ribulose-phosphate 3-epimerase YP_001836664.1 1930443 R 516950 CDS YP_001836665.1 182684918 6216494 complement(1931110..1931988) 1 NC_010582.1 EngC; RsgA; CpgA; circularly permuted GTPase; ribosome small subunit-dependent GTPase A; has the pattern G4-G1-G3 as opposed to other GTPases; interacts strongly with 30S ribosome which stimulates GTPase activity; ribosome-associated GTPase 1931988 6216494 SPCG_1947 Streptococcus pneumoniae CGSP14 ribosome-associated GTPase YP_001836665.1 1931110 R 516950 CDS YP_001836666.1 182684919 6216933 complement(1931990..1932862) 1 NC_010582.1 catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin; dimethyladenosine transferase 1932862 ksgA 6216933 ksgA Streptococcus pneumoniae CGSP14 dimethyladenosine transferase YP_001836666.1 1931990 R 516950 CDS YP_001836667.1 182684920 6216342 complement(1932993..1933307) 1 NC_010582.1 hypothetical protein 1933307 6216342 SPCG_1949 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836667.1 1932993 R 516950 CDS YP_001836668.1 182684921 6218233 complement(1933294..1933935) 1 NC_010582.1 ABC transporter ATP-binding protein 1933935 6218233 SPCG_1950 Streptococcus pneumoniae CGSP14 ABC transporter ATP-binding protein YP_001836668.1 1933294 R 516950 CDS YP_001836669.1 182684922 6216508 complement(1933937..1935979) 1 NC_010582.1 immunity protein 1935979 6216508 SPCG_1951 Streptococcus pneumoniae CGSP14 immunity protein YP_001836669.1 1933937 R 516950 CDS YP_001836670.1 182684923 6217179 complement(1936044..1936340) 1 NC_010582.1 hypothetical protein 1936340 6217179 SPCG_1952 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836670.1 1936044 R 516950 CDS YP_001836671.1 182684924 6216846 complement(1936660..1937559) 1 NC_010582.1 transcriptional regulator PlcR 1937559 plcR 6216846 plcR Streptococcus pneumoniae CGSP14 transcriptional regulator PlcR YP_001836671.1 1936660 R 516950 CDS YP_001836672.1 182684925 6217014 complement(1937631..1938191) 1 NC_010582.1 primase-like protein 1938191 6217014 SPCG_1954 Streptococcus pneumoniae CGSP14 primase-like protein YP_001836672.1 1937631 R 516950 CDS YP_001836673.1 182684926 6217177 complement(1938191..1938964) 1 NC_010582.1 hydrolase 1938964 6217177 SPCG_1955 Streptococcus pneumoniae CGSP14 hydrolase YP_001836673.1 1938191 R 516950 CDS YP_001836674.1 182684927 6216669 1939161..1939253 1 NC_010582.1 hypothetical protein 1939253 6216669 SPCG_1956 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836674.1 1939161 D 516950 CDS YP_001836675.1 182684928 6218102 complement(1939269..1940168) 1 NC_010582.1 cell wall surface anchor family protein 1940168 6218102 SPCG_1957 Streptococcus pneumoniae CGSP14 cell wall surface anchor family protein YP_001836675.1 1939269 R 516950 CDS YP_001836676.1 182684929 6218285 complement(1940452..1940586) 1 NC_010582.1 in Escherichia coli transcription of this gene is enhanced by polyamines; 50S ribosomal protein L34 1940586 rpmH 6218285 rpmH Streptococcus pneumoniae CGSP14 50S ribosomal protein L34 YP_001836676.1 1940452 R 516950 CDS YP_001836677.1 182684930 6217251 complement(1940731..1941945) 1 NC_010582.1 broad specificity; family IV; in Corynebacterium glutamicum this protein can use glutamate, 2-aminobutyrate, and aspartate as amino donors and pyruvate as the acceptor; aminotransferase AlaT 1941945 aspC 6217251 aspC Streptococcus pneumoniae CGSP14 aminotransferase AlaT YP_001836677.1 1940731 R 516950 CDS YP_001836678.1 182684931 6216576 complement(1942101..1942409) 1 NC_010582.1 hypothetical protein 1942409 6216576 SPCG_1960 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836678.1 1942101 R 516950 CDS YP_001836679.1 182684932 6216977 1942493..1943008 1 NC_010582.1 universal stress protein 1943008 6216977 SPCG_1961 Streptococcus pneumoniae CGSP14 universal stress protein YP_001836679.1 1942493 D 516950 CDS YP_001836680.1 182684933 6216803 complement(1943043..1944461) 1 NC_010582.1 cof family protein 1944461 6216803 SPCG_1962 Streptococcus pneumoniae CGSP14 cof family protein YP_001836680.1 1943043 R 516950 CDS YP_001836681.1 182684934 6217728 1944497..1945459 1 NC_010582.1 L-asparaginase 1945459 ansB 6217728 ansB Streptococcus pneumoniae CGSP14 L-asparaginase YP_001836681.1 1944497 D 516950 CDS YP_001836682.1 182684935 6216676 complement(1945755..1946795) 1 NC_010582.1 catabolite control protein A 1946795 ccpA 6216676 ccpA Streptococcus pneumoniae CGSP14 catabolite control protein A YP_001836682.1 1945755 R 516950 CDS YP_001836683.1 182684936 6218271 complement(1947189..1947788) 1 NC_010582.1 DNA-binding response regulator 1947788 6218271 SPCG_1966 Streptococcus pneumoniae CGSP14 DNA-binding response regulator YP_001836683.1 1947189 R 516950 CDS YP_001836684.1 182684937 6216611 complement(1947789..1948886) 1 NC_010582.1 sensor histidine kinase 1948886 6216611 SPCG_1967 Streptococcus pneumoniae CGSP14 sensor histidine kinase YP_001836684.1 1947789 R 516950 CDS YP_001836685.1 182684938 6216964 complement(1948886..1949689) 1 NC_010582.1 hypothetical protein 1949689 6216964 SPCG_1968 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836685.1 1948886 R 516950 CDS YP_001836686.1 182684939 6216517 complement(1949625..1950509) 1 NC_010582.1 ABC transporter ATP-binding protein 1950509 6216517 SPCG_1969 Streptococcus pneumoniae CGSP14 ABC transporter ATP-binding protein YP_001836686.1 1949625 R 516950 CDS YP_001836687.1 182684940 6217924 complement(1950496..1950690) 1 NC_010582.1 hypothetical protein 1950690 6217924 SPCG_1970 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836687.1 1950496 R 516950 CDS YP_001836688.1 182684941 6217978 complement(1950777..1950893) 1 NC_010582.1 hypothetical protein 1950893 6217978 SPCG_1971 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836688.1 1950777 R 516950 CDS YP_001836689.1 182684942 6217616 complement(1957572..1958051) 1 NC_010582.1 competence-specific global transcription modulator 1958051 comX2 6217616 comX2 Streptococcus pneumoniae CGSP14 competence-specific global transcription modulator YP_001836689.1 1957572 R 516950 CDS YP_001836690.1 182684943 6218156 complement(1958173..1958724) 1 NC_010582.1 Modulates Rho-dependent transcription termination; transcription antitermination protein NusG 1958724 nusG 6218156 nusG Streptococcus pneumoniae CGSP14 transcription antitermination protein NusG YP_001836690.1 1958173 R 516950 CDS YP_001836691.1 182684944 6217293 complement(1958764..1958940) 1 NC_010582.1 forms a complex with SecY and SecG; SecYEG forms a protein-conducting channel to which secA binds and translocates targeted polypeptides across the cytoplasmic membrane, a process driven by ATP and a proton-motive force; preprotein translocase subunit SecE 1958940 secE 6217293 secE Streptococcus pneumoniae CGSP14 preprotein translocase subunit SecE YP_001836691.1 1958764 R 516950 CDS YP_001836692.1 182684945 6216626 1959245..1960516 1 NC_010582.1 IS1202 transposase 1960516 6216626 SPCG_1975 Streptococcus pneumoniae CGSP14 IS1202 transposase YP_001836692.1 1959245 D 516950 CDS YP_001836693.1 182684946 6218175 complement(1960934..1963129) 1 NC_010582.1 penicillin-binding protein 2A 1963129 pbp2A 6218175 pbp2A Streptococcus pneumoniae CGSP14 penicillin-binding protein 2A YP_001836693.1 1960934 R 516950 CDS YP_001836694.1 182684947 6218006 1963216..1964091 1 NC_010582.1 ribosomal large subunit pseudouridine synthase D 1964091 rluD 6218006 rluD Streptococcus pneumoniae CGSP14 ribosomal large subunit pseudouridine synthase D YP_001836694.1 1963216 D 516950 CDS YP_001836695.1 182684948 6217495 1964197..1965489 1 NC_010582.1 IS1167, transposase 1965489 6217495 SPCG_1978 Streptococcus pneumoniae CGSP14 IS1167, transposase YP_001836695.1 1964197 D 516950 CDS YP_001836696.1 182684949 6217456 complement(1965579..1966658) 1 NC_010582.1 glyceraldehyde-3-phosphate dehydrogenase 1966658 gapA 6217456 gapA Streptococcus pneumoniae CGSP14 glyceraldehyde-3-phosphate dehydrogenase YP_001836696.1 1965579 R 516950 CDS YP_001836697.1 182684950 6217581 complement(1966806..1967765) 1 NC_010582.1 hypothetical protein 1967765 6217581 SPCG_1980 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836697.1 1966806 R 516950 CDS YP_001836698.1 182684951 6217655 complement(1967851..1968189) 1 NC_010582.1 IS630-Spn1, transposase Orf2 1968189 6217655 SPCG_1981 Streptococcus pneumoniae CGSP14 IS630-Spn1, transposase Orf2 YP_001836698.1 1967851 R 516950 CDS YP_001836699.1 182684952 6217983 complement(1968347..1968715) 1 NC_010582.1 IS630-Spn1, transposase Orf1 1968715 6217983 SPCG_1982 Streptococcus pneumoniae CGSP14 IS630-Spn1, transposase Orf1 YP_001836699.1 1968347 R 516950 CDS YP_001836700.1 182684953 6217817 complement(1968828..1969727) 1 NC_010582.1 catalyzes the formation of pyridine-2,3-dicarboxylate and 5-phospho-alpha-D-ribose 1-diphosphate from nictinate D-ribonucleotide; nicotinate-nucleotide pyrophosphorylase 1969727 nadC 6217817 nadC Streptococcus pneumoniae CGSP14 nicotinate-nucleotide pyrophosphorylase YP_001836700.1 1968828 R 516950 CDS YP_001836701.1 182684954 6218099 1969937..1971247 1 NC_010582.1 membrane protein 1971247 6218099 SPCG_1984 Streptococcus pneumoniae CGSP14 membrane protein YP_001836701.1 1969937 D 516950 CDS YP_001836702.1 182684955 6217944 complement(1971629..1971823) 1 NC_010582.1 hypothetical protein 1971823 6217944 SPCG_1985 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836702.1 1971629 R 516950 CDS YP_001836703.1 182684956 6216610 complement(1972283..1973011) 1 NC_010582.1 GntR family transcriptional regulator 1973011 6216610 SPCG_1986 Streptococcus pneumoniae CGSP14 GntR family transcriptional regulator YP_001836703.1 1972283 R 516950 CDS YP_001836704.1 182684957 6218254 1973127..1974578 1 NC_010582.1 glycosyl hydrolase family protein 1974578 6218254 SPCG_1987 Streptococcus pneumoniae CGSP14 glycosyl hydrolase family protein YP_001836704.1 1973127 D 516950 CDS YP_001836705.1 182684958 6217547 1974596..1975891 1 NC_010582.1 PTS system transporter subunit IIC 1975891 6217547 SPCG_1988 Streptococcus pneumoniae CGSP14 PTS system transporter subunit IIC YP_001836705.1 1974596 D 516950 CDS YP_001836706.1 182684959 6218262 1975857..1976204 1 NC_010582.1 PTS system transporter subunit IIB 1976204 6218262 SPCG_1989 Streptococcus pneumoniae CGSP14 PTS system transporter subunit IIB YP_001836706.1 1975857 D 516950 CDS YP_001836707.1 182684960 6216835 1976183..1976509 1 NC_010582.1 PTS system transporter subunit IIA 1976509 6216835 SPCG_1990 Streptococcus pneumoniae CGSP14 PTS system transporter subunit IIA YP_001836707.1 1976183 D 516950 CDS YP_001836708.1 182684961 6218220 complement(1977495..1980167) 1 NC_010582.1 bifunctional acetaldehyde-CoA/alcohol dehydrogenase 1980167 adhE 6218220 adhE Streptococcus pneumoniae CGSP14 bifunctional acetaldehyde-CoA/alcohol dehydrogenase YP_001836708.1 1977495 R 516950 CDS YP_001836709.1 182684962 6217700 complement(1980446..1980856) 1 NC_010582.1 hypothetical protein 1980856 6217700 SPCG_1992 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836709.1 1980446 R 516950 CDS YP_001836710.1 182684963 6217267 complement(1980858..1981286) 1 NC_010582.1 phosphotyrosine protein phosphatase 1981286 6217267 SPCG_1993 Streptococcus pneumoniae CGSP14 phosphotyrosine protein phosphatase YP_001836710.1 1980858 R 516950 CDS YP_001836711.1 182684964 6218203 complement(1981333..1981632) 1 NC_010582.1 member of preprotein translocase; forms a heterotrimer with SecD and SecF; links the SecD/SecF/YajC/YidC complex with the SecY/SecE/SecG complex; preprotein translocase subunit YajC 1981632 yajC 6218203 yajC Streptococcus pneumoniae CGSP14 preprotein translocase subunit YajC YP_001836711.1 1981333 R 516950 CDS YP_001836712.1 182684965 6217649 complement(1981749..1983725) 1 NC_010582.1 catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase; transketolase 1983725 tktA 6217649 tktA Streptococcus pneumoniae CGSP14 transketolase YP_001836712.1 1981749 R 516950 CDS YP_001836713.1 182684966 6217873 complement(1983839..1984930) 1 NC_010582.1 L-ascorbate 6-phosphate lactonase 1984930 6217873 SPCG_1996 Streptococcus pneumoniae CGSP14 L-ascorbate 6-phosphate lactonase YP_001836713.1 1983839 R 516950 CDS YP_001836714.1 182684967 6218291 complement(1985042..1986715) 1 NC_010582.1 BglG family transcriptional regulator 1986715 6218291 SPCG_1997 Streptococcus pneumoniae CGSP14 BglG family transcriptional regulator YP_001836714.1 1985042 R 516950 CDS YP_001836715.1 182684968 6218178 complement(1986894..1987598) 1 NC_010582.1 catalyzes the formation of D-xylulose 5-phosphate from L-ribulose 5-phosphate in the L-arabinose and L-ascorbate degradation pathways; L-ribulose-5-phosphate 4-epimerase 1987598 araD 6218178 araD Streptococcus pneumoniae CGSP14 L-ribulose-5-phosphate 4-epimerase YP_001836715.1 1986894 R 516950 CDS YP_001836716.1 182684969 6217253 complement(1987600..1988061) 1 NC_010582.1 hexulose-6-phosphate isomerase 1988061 6217253 SPCG_1999 Streptococcus pneumoniae CGSP14 hexulose-6-phosphate isomerase YP_001836716.1 1987600 R 516950 CDS YP_001836717.1 182684970 6218154 complement(1988102..1988458) 1 NC_010582.1 hexulose-6-phosphate isomerase 1988458 6218154 SPCG_2000 Streptococcus pneumoniae CGSP14 hexulose-6-phosphate isomerase YP_001836717.1 1988102 R 516950 CDS YP_001836718.1 182684971 6217479 complement(1988462..1989127) 1 NC_010582.1 catalyzes the formation of L-xylulose-5-phosphate from 3-keto-L-gulonate-6-phosphate in anaerobic L-ascorbate utilization; 3-keto-L-gulonate-6-phosphate decarboxylase 1989127 ulaD 6217479 ulaD Streptococcus pneumoniae CGSP14 3-keto-L-gulonate-6-phosphate decarboxylase YP_001836718.1 1988462 R 516950 CDS YP_001836719.1 182684972 6217346 complement(1989144..1989629) 1 NC_010582.1 PTS system transporter subunit IIA 1989629 6217346 SPCG_2002 Streptococcus pneumoniae CGSP14 PTS system transporter subunit IIA YP_001836719.1 1989144 R 516950 CDS YP_001836720.1 182684973 6218255 complement(1989706..1989987) 1 NC_010582.1 PTS system transporter subunit IIB 1989987 6218255 SPCG_2003 Streptococcus pneumoniae CGSP14 PTS system transporter subunit IIB YP_001836720.1 1989706 R 516950 CDS YP_001836721.1 182684974 6217829 complement(1990010..1991536) 1 NC_010582.1 membrane component; functions with enzymes IIB (sgaB; ulaB) and IIA (sgaA; ulaC) enzyme I and HPr for anaerobic utilization and uptake of L-ascorbate; sgaTBA are regulated by yifQ as well as Crp and Fnr; PTS system ascorbate-specific transporter subunit IIC 1991536 ulaA 6217829 ulaA Streptococcus pneumoniae CGSP14 PTS system ascorbate-specific transporter subunit IIC YP_001836721.1 1990010 R 516950 CDS YP_001836722.1 182684975 6218038 complement(1991598..1992221) 1 NC_010582.1 hypothetical protein 1992221 6218038 SPCG_2005 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836722.1 1991598 R 516950 CDS YP_001836723.1 182684976 6217507 complement(1992272..1993258) 1 NC_010582.1 jag protein 1993258 6217507 SPCG_2006 Streptococcus pneumoniae CGSP14 jag protein YP_001836723.1 1992272 R 516950 CDS YP_001836724.1 182684977 6218177 complement(1993277..1994107) 1 NC_010582.1 spoIIIJ family protein 1994107 6218177 SPCG_2007 Streptococcus pneumoniae CGSP14 spoIIIJ family protein YP_001836724.1 1993277 R 516950 CDS YP_001836725.1 182684978 6217901 complement(1994076..1994447) 1 NC_010582.1 protein component of RNaseP which catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'terminus; this enzyme also cleaves other RNA substrates; ribonuclease P 1994447 rnpA 6217901 rnpA Streptococcus pneumoniae CGSP14 ribonuclease P YP_001836725.1 1994076 R 516950 CDS YP_001836726.1 182684979 6216703 complement(1994464..1994595) 1 NC_010582.1 hypothetical protein 1994595 6216703 SPCG_2009 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836726.1 1994464 R 516950 CDS YP_001836727.1 182684980 6216608 complement(1994596..1995816) 1 NC_010582.1 AckA utilizes acetate and can acetylate CheY which increases signal strength during flagellar rotation; utilizes magnesium and ATP; also involved in conversion of acetate to aceyl-CoA; acetate kinase 1995816 6216608 SPCG_2010 Streptococcus pneumoniae CGSP14 acetate kinase YP_001836727.1 1994596 R 516950 CDS YP_001836728.1 182684981 6217994 complement(1995837..1996790) 1 NC_010582.1 hypothetical protein 1996790 6217994 SPCG_2011 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836728.1 1995837 R 516950 CDS YP_001836729.1 182684982 6218243 complement(1996851..1997231) 1 NC_010582.1 hypothetical protein 1997231 6218243 SPCG_2012 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836729.1 1996851 R 516950 CDS YP_001836730.1 182684983 6216333 complement(1997263..1997445) 1 NC_010582.1 hypothetical protein 1997445 6216333 SPCG_2013 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836730.1 1997263 R 516950 CDS YP_001836731.1 182684984 6217241 complement(1997548..1997994) 1 NC_010582.1 hypothetical protein 1997994 6217241 SPCG_2014 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836731.1 1997548 R 516950 CDS YP_001836732.1 182684985 6217681 complement(1997972..1998379) 1 NC_010582.1 hypothetical protein 1998379 6217681 SPCG_2015 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836732.1 1997972 R 516950 CDS YP_001836733.1 182684986 6217598 complement(1998396..1998656) 1 NC_010582.1 hypothetical protein 1998656 6217598 SPCG_2016 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836733.1 1998396 R 516950 CDS YP_001836734.1 182684987 6218222 complement(1998661..1999089) 1 NC_010582.1 competence protein CglD 1999089 cglD 6218222 cglD Streptococcus pneumoniae CGSP14 competence protein CglD YP_001836734.1 1998661 R 516950 CDS YP_001836735.1 182684988 6218121 complement(1999058..1999384) 1 NC_010582.1 competence protein CglC 1999384 cglC 6218121 cglC Streptococcus pneumoniae CGSP14 competence protein CglC YP_001836735.1 1999058 R 516950 CDS YP_001836736.1 182684989 6217904 complement(1999386..2000429) 1 NC_010582.1 competence protein CglB 2000429 cglB 6217904 cglB Streptococcus pneumoniae CGSP14 competence protein CglB YP_001836736.1 1999386 R 516950 CDS YP_001836737.1 182684990 6217902 complement(2000350..2001291) 1 NC_010582.1 competence protein CglA 2001291 cglA 6217902 cglA Streptococcus pneumoniae CGSP14 competence protein CglA YP_001836737.1 2000350 R 516950 CDS YP_001836738.1 182684991 6217832 complement(2001367..2001738) 1 NC_010582.1 hypothetical protein 2001738 6217832 SPCG_2021 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836738.1 2001367 R 516950 CDS YP_001836739.1 182684992 6217891 complement(2001883..2002941) 1 NC_010582.1 zinc-containing alcohol dehydrogenase 2002941 adh 6217891 adh Streptococcus pneumoniae CGSP14 zinc-containing alcohol dehydrogenase YP_001836739.1 2001883 R 516950 CDS YP_001836740.1 182684993 6217147 complement(2003104..2004255) 1 NC_010582.1 N-acetylglucosamine-6-phosphate deacetylase 2004255 nagA 6217147 nagA Streptococcus pneumoniae CGSP14 N-acetylglucosamine-6-phosphate deacetylase YP_001836740.1 2003104 R 516950 CDS YP_001836741.1 182684994 6218301 complement(2004408..2006225) 1 NC_010582.1 hypothetical protein 2006225 6218301 SPCG_2024 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836741.1 2004408 R 516950 CDS YP_001836742.1 182684995 6217333 complement(2006326..2007468) 1 NC_010582.1 Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr); queuine tRNA-ribosyltransferase 2007468 tgt 6217333 tgt Streptococcus pneumoniae CGSP14 queuine tRNA-ribosyltransferase YP_001836742.1 2006326 R 516950 CDS YP_001836743.1 182684996 6217860 2007598..2008455 1 NC_010582.1 hypothetical protein 2008455 6217860 SPCG_2026 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836743.1 2007598 D 516950 CDS YP_001836744.1 182684997 6218261 complement(2008483..2009127) 1 NC_010582.1 catalyzes the removal of 5-oxoproline from various penultimate amino acid residues except L-proline; pyrrolidone-carboxylate peptidase 2009127 6218261 SPCG_2027 Streptococcus pneumoniae CGSP14 pyrrolidone-carboxylate peptidase YP_001836744.1 2008483 R 516950 CDS YP_001836745.1 182684998 6217508 complement(2009234..2009593) 1 NC_010582.1 hypothetical protein 2009593 6217508 SPCG_2028 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836745.1 2009234 R 516950 CDS YP_001836746.1 182684999 6217840 complement(2009604..2010029) 1 NC_010582.1 MarR family transcriptional regulator 2010029 marR 6217840 marR Streptococcus pneumoniae CGSP14 MarR family transcriptional regulator YP_001836746.1 2009604 R 516950 CDS YP_001836747.1 182685000 6217820 complement(2010349..2011461) 1 NC_010582.1 lysM domain-containing protein 2011461 6217820 SPCG_2030 Streptococcus pneumoniae CGSP14 lysM domain-containing protein YP_001836747.1 2010349 R 516950 CDS YP_001836748.1 182685001 6217835 complement(2011627..2012247) 1 NC_010582.1 HAD superfamily hydrolase 2012247 6217835 SPCG_2031 Streptococcus pneumoniae CGSP14 HAD superfamily hydrolase YP_001836748.1 2011627 R 516950 CDS YP_001836749.1 182685002 6218071 complement(2012251..2013531) 1 NC_010582.1 MATE efflux family protein 2013531 6218071 SPCG_2032 Streptococcus pneumoniae CGSP14 MATE efflux family protein YP_001836749.1 2012251 R 516950 CDS YP_001836750.1 182685003 6218134 complement(2013592..2015076) 1 NC_010582.1 catalyzes the formation of L-threonine from O-phospho-L-homoserine; threonine synthase 2015076 thrC 6218134 thrC Streptococcus pneumoniae CGSP14 threonine synthase YP_001836750.1 2013592 R 516950 CDS YP_001836751.1 182685004 6218212 complement(2015152..2016429) 1 NC_010582.1 hypothetical protein 2016429 6218212 SPCG_2034 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836751.1 2015152 R 516950 CDS YP_001836752.1 182685005 6218067 complement(2022891..2023325) 1 NC_010582.1 cytidine/deoxycytidylate deaminase family protein 2023325 6218067 SPCG_2035 Streptococcus pneumoniae CGSP14 cytidine/deoxycytidylate deaminase family protein YP_001836752.1 2022891 R 516950 CDS YP_001836753.1 182685006 6217819 complement(2023339..2024799) 1 NC_010582.1 Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation; glutamyl-tRNA synthetase 2024799 gltX 6217819 gltX Streptococcus pneumoniae CGSP14 glutamyl-tRNA synthetase YP_001836753.1 2023339 R 516950 CDS YP_001836754.1 182685007 6218183 complement(2024923..2026272) 1 NC_010582.1 functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis; catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate; member of PGI family; glucose-6-phosphate isomerase 2026272 pgi 6218183 pgi Streptococcus pneumoniae CGSP14 glucose-6-phosphate isomerase YP_001836754.1 2024923 R 516950 CDS YP_001836755.1 182685008 6217144 complement(2026259..2026438) 1 NC_010582.1 hypothetical protein 2026438 6217144 SPCG_2038 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836755.1 2026259 R 516950 CDS YP_001836756.1 182685009 6218044 complement(2026442..2027179) 1 NC_010582.1 glutamine amidotransferase, class-I 2027179 guaA 6218044 guaA Streptococcus pneumoniae CGSP14 glutamine amidotransferase, class-I YP_001836756.1 2026442 R 516950 CDS YP_001836757.1 182685010 6218192 complement(2027270..2029081) 1 NC_010582.1 ABC transporter ATP-binding protein/permease 2029081 6218192 SPCG_2040 Streptococcus pneumoniae CGSP14 ABC transporter ATP-binding protein/permease YP_001836757.1 2027270 R 516950 CDS YP_001836758.1 182685011 6216869 2029183..2029497 1 NC_010582.1 degenerate transposase 2029497 6216869 SPCG_2041 Streptococcus pneumoniae CGSP14 degenerate transposase YP_001836758.1 2029183 D 516950 CDS YP_001836759.1 182685012 6217184 complement(2029828..2031522) 1 NC_010582.1 ABC transporter ATP-binding protein/permease 2031522 6217184 SPCG_2042 Streptococcus pneumoniae CGSP14 ABC transporter ATP-binding protein/permease YP_001836759.1 2029828 R 516950 CDS YP_001836760.1 182685013 6217823 complement(2031669..2034242) 1 NC_010582.1 This protein performs the mismatch recognition step during the DNA repair process; DNA mismatch repair protein MutS 2034242 hexA 6217823 hexA Streptococcus pneumoniae CGSP14 DNA mismatch repair protein MutS YP_001836760.1 2031669 R 516950 CDS YP_001836761.1 182685014 6218047 complement(2034254..2034700) 1 NC_010582.1 transcriptional repressor 2034700 argR 6218047 argR Streptococcus pneumoniae CGSP14 transcriptional repressor YP_001836761.1 2034254 R 516950 CDS YP_001836762.1 182685015 6217861 2034836..2036527 1 NC_010582.1 catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase; arginyl-tRNA synthetase 2036527 argS 6217861 argS Streptococcus pneumoniae CGSP14 arginyl-tRNA synthetase YP_001836762.1 2034836 D 516950 CDS YP_001836763.1 182685016 6217985 complement(2036842..2037231) 1 NC_010582.1 IS1381 transposase protein B 2037231 6217985 SPCG_2046 Streptococcus pneumoniae CGSP14 IS1381 transposase protein B YP_001836763.1 2036842 R 516950 CDS YP_001836764.1 182685017 6218264 2037362..2037871 1 NC_010582.1 hypothetical protein 2037871 6218264 SPCG_2047 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836764.1 2037362 D 516950 CDS YP_001836765.1 182685018 6216855 2037955..2038665 1 NC_010582.1 response regulator 2038665 6216855 SPCG_2048 Streptococcus pneumoniae CGSP14 response regulator YP_001836765.1 2037955 D 516950 CDS YP_001836766.1 182685019 6217588 2038662..2039993 1 NC_010582.1 sensor histidine kinase PnpS 2039993 6217588 SPCG_2049 Streptococcus pneumoniae CGSP14 sensor histidine kinase PnpS YP_001836766.1 2038662 D 516950 CDS YP_001836767.1 182685020 6217900 2040097..2041035 1 NC_010582.1 phosphate ABC transporter substrate-binding protein 2041035 6217900 SPCG_2050 Streptococcus pneumoniae CGSP14 phosphate ABC transporter substrate-binding protein YP_001836767.1 2040097 D 516950 CDS YP_001836768.1 182685021 6218132 2041153..2042016 1 NC_010582.1 phosphate ABC transporter permease 2042016 6218132 SPCG_2051 Streptococcus pneumoniae CGSP14 phosphate ABC transporter permease YP_001836768.1 2041153 D 516950 CDS YP_001836769.1 182685022 6217856 2042009..2042824 1 NC_010582.1 phosphate ABC transporter permease 2042824 6217856 SPCG_2052 Streptococcus pneumoniae CGSP14 phosphate ABC transporter permease YP_001836769.1 2042009 D 516950 CDS YP_001836770.1 182685023 6217541 2042826..2043578 1 NC_010582.1 ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation; phosphate transporter ATP-binding protein 2043578 6217541 SPCG_2053 Streptococcus pneumoniae CGSP14 phosphate transporter ATP-binding protein YP_001836770.1 2042826 D 516950 CDS YP_001836771.1 182685024 6217656 2043593..2044243 1 NC_010582.1 phosphate transport system regulatory protein PhoU 2044243 phoU 6217656 phoU Streptococcus pneumoniae CGSP14 phosphate transport system regulatory protein PhoU YP_001836771.1 2043593 D 516950 CDS YP_001836772.1 182685025 6217898 2044311..2044736 1 NC_010582.1 degenerate transposase 2044736 6217898 SPCG_2055 Streptococcus pneumoniae CGSP14 degenerate transposase YP_001836772.1 2044311 D 516950 CDS YP_001836773.1 182685026 6217472 complement(2044910..2045368) 1 NC_010582.1 transcriptional regulator 2045368 6217472 SPCG_2056 Streptococcus pneumoniae CGSP14 transcriptional regulator YP_001836773.1 2044910 R 516950 CDS YP_001836774.1 182685027 6216735 2045502..2046518 1 NC_010582.1 catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate; NAD(P)H-dependent glycerol-3-phosphate dehydrogenase 2046518 gpsA 6216735 gpsA Streptococcus pneumoniae CGSP14 NAD(P)H-dependent glycerol-3-phosphate dehydrogenase YP_001836774.1 2045502 D 516950 CDS YP_001836775.1 182685028 6218025 2046540..2047439 1 NC_010582.1 UTP-glucose-1-phosphate uridylyltransferase 2047439 galU 6218025 galU Streptococcus pneumoniae CGSP14 UTP-glucose-1-phosphate uridylyltransferase YP_001836775.1 2046540 D 516950 CDS YP_001836776.1 182685029 6216919 complement(2047506..2048186) 1 NC_010582.1 hypothetical protein 2048186 6216919 SPCG_2059 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836776.1 2047506 R 516950 CDS YP_001836777.1 182685030 6217941 complement(2048167..2048712) 1 NC_010582.1 5-formyltetrahydrofolate cyclo-ligase 2048712 6217941 SPCG_2060 Streptococcus pneumoniae CGSP14 5-formyltetrahydrofolate cyclo-ligase YP_001836777.1 2048167 R 516950 CDS YP_001836778.1 182685031 6218235 complement(2048718..2049848) 1 NC_010582.1 M20/M25/M40 family peptidase 2049848 6218235 SPCG_2061 Streptococcus pneumoniae CGSP14 M20/M25/M40 family peptidase YP_001836778.1 2048718 R 516950 CDS YP_001836779.1 182685032 6217467 complement(2049916..2050614) 1 NC_010582.1 2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase 2050614 6217467 SPCG_2062 Streptococcus pneumoniae CGSP14 2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase YP_001836779.1 2049916 R 516950 CDS YP_001836780.1 182685033 6217695 complement(2050844..2051929) 1 NC_010582.1 hypothetical protein 2051929 6217695 SPCG_2063 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836780.1 2050844 R 516950 CDS YP_001836781.1 182685034 6217798 complement(2051820..2054297) 1 NC_010582.1 penicillin-binding protein 1B 2054297 pbp1B 6217798 pbp1B Streptococcus pneumoniae CGSP14 penicillin-binding protein 1B YP_001836781.1 2051820 R 516950 CDS YP_001836782.1 182685035 6217431 2054427..2055683 1 NC_010582.1 catalyzes the formation of tyrosyl-tRNA(Tyr) from tyrosine and tRNA(Tyr); tyrosyl-tRNA synthetase 2055683 tyrS 6217431 tyrS Streptococcus pneumoniae CGSP14 tyrosyl-tRNA synthetase YP_001836782.1 2054427 D 516950 CDS YP_001836783.1 182685036 6217908 complement(2055761..2057833) 1 NC_010582.1 cation transporter E1-E2 family ATPase 2057833 ctpC 6217908 ctpC Streptococcus pneumoniae CGSP14 cation transporter E1-E2 family ATPase YP_001836783.1 2055761 R 516950 CDS YP_001836784.1 182685037 6218110 complement(2057826..2058137) 1 NC_010582.1 hypothetical protein 2058137 6218110 SPCG_2067 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836784.1 2057826 R 516950 CDS YP_001836785.1 182685038 6217116 2058256..2059104 1 NC_010582.1 rRNA (guanine-N1-)-methyltransferase 2059104 rrmA 6217116 rrmA Streptococcus pneumoniae CGSP14 rRNA (guanine-N1-)-methyltransferase YP_001836785.1 2058256 D 516950 CDS YP_001836786.1 182685039 6217946 2059727..2060299 1 NC_010582.1 hypothetical protein 2060299 6217946 SPCG_2069 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836786.1 2059727 D 516950 CDS YP_001836787.1 182685040 6217471 complement(2061344..2063602) 1 NC_010582.1 glycogen phosphorylase family protein 2063602 malP 6217471 malP Streptococcus pneumoniae CGSP14 glycogen phosphorylase family protein YP_001836787.1 2061344 R 516950 CDS YP_001836788.1 182685041 6217466 complement(2063628..2065145) 1 NC_010582.1 amylomaltase; acts to release glucose from maltodextrins; 4-alpha-glucanotransferase 2065145 malM 6217466 malM Streptococcus pneumoniae CGSP14 4-alpha-glucanotransferase YP_001836788.1 2063628 R 516950 CDS YP_001836789.1 182685042 6217619 2065614..2066966 1 NC_010582.1 maltose/maltodextrin ABC transporter maltose/maltodextrin-binding protein 2066966 6217619 SPCG_2072 Streptococcus pneumoniae CGSP14 maltose/maltodextrin ABC transporter maltose/maltodextrin-binding protein YP_001836789.1 2065614 D 516950 CDS YP_001836790.1 182685043 6217668 2067062..2068369 1 NC_010582.1 maltodextrin ABC transporter permease 2068369 6217668 SPCG_2073 Streptococcus pneumoniae CGSP14 maltodextrin ABC transporter permease YP_001836790.1 2067062 D 516950 CDS YP_001836791.1 182685044 6218090 2068350..2069213 1 NC_010582.1 maltodextrin ABC transporter permease 2069213 6218090 SPCG_2074 Streptococcus pneumoniae CGSP14 maltodextrin ABC transporter permease YP_001836791.1 2068350 D 516950 CDS YP_001836792.1 182685045 6217405 2069466..2070266 1 NC_010582.1 malA protein 2070266 malA 6217405 malA Streptococcus pneumoniae CGSP14 malA protein YP_001836792.1 2069466 D 516950 CDS YP_001836793.1 182685046 6218142 2070276..2071262 1 NC_010582.1 maltose operon transcriptional repressor 2071262 malR 6218142 malR Streptococcus pneumoniae CGSP14 maltose operon transcriptional repressor YP_001836793.1 2070276 D 516950 CDS YP_001836794.1 182685047 6218051 2071311..2071646 1 NC_010582.1 hypothetical protein 2071646 6218051 SPCG_2077 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836794.1 2071311 D 516950 CDS YP_001836795.1 182685048 6217828 complement(2071688..2072629) 1 NC_010582.1 hypothetical protein 2072629 6217828 SPCG_2078 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836795.1 2071688 R 516950 CDS YP_001836796.1 182685049 6217537 complement(2072607..2074370) 1 NC_010582.1 catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes; aspartyl-tRNA synthetase 2074370 aspS 6217537 aspS Streptococcus pneumoniae CGSP14 aspartyl-tRNA synthetase YP_001836796.1 2072607 R 516950 CDS YP_001836797.1 182685050 6217672 complement(2074489..2074680) 1 NC_010582.1 hypothetical protein 2074680 6217672 SPCG_2080 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836797.1 2074489 R 516950 CDS YP_001836798.1 182685051 6218081 complement(2074722..2074952) 1 NC_010582.1 hypothetical protein 2074952 6218081 SPCG_2081 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836798.1 2074722 R 516950 CDS YP_001836799.1 182685052 6216521 complement(2074970..2075611) 1 NC_010582.1 hypothetical protein 2075611 6216521 SPCG_2082 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836799.1 2074970 R 516950 CDS YP_001836800.1 182685053 6217919 complement(2075623..2076351) 1 NC_010582.1 hypothetical protein 2076351 6217919 SPCG_2083 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836800.1 2075623 R 516950 CDS YP_001836801.1 182685054 6218072 complement(2076348..2076548) 1 NC_010582.1 hypothetical protein 2076548 6218072 SPCG_2084 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836801.1 2076348 R 516950 CDS YP_001836802.1 182685055 6216836 complement(2076545..2076760) 1 NC_010582.1 transcriptional regulator 2076760 6216836 SPCG_2085 Streptococcus pneumoniae CGSP14 transcriptional regulator YP_001836802.1 2076545 R 516950 CDS YP_001836803.1 182685056 6217699 complement(2076761..2077228) 1 NC_010582.1 hypothetical protein 2077228 6217699 SPCG_2086 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836803.1 2076761 R 516950 CDS YP_001836804.1 182685057 6217865 complement(2077228..2077401) 1 NC_010582.1 hypothetical protein 2077401 6217865 SPCG_2087 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836804.1 2077228 R 516950 CDS YP_001836805.1 182685058 6218101 complement(2077461..2078750) 1 NC_010582.1 catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG; histidyl-tRNA synthetase 2078750 hisS 6218101 hisS Streptococcus pneumoniae CGSP14 histidyl-tRNA synthetase YP_001836805.1 2077461 R 516950 CDS YP_001836806.1 182685059 6217885 complement(2078828..2080075) 1 NC_010582.1 hypothetical protein 2080075 6217885 SPCG_2089 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836806.1 2078828 R 516950 CDS YP_001836807.1 182685060 6217948 2080292..2081638 1 NC_010582.1 IS1380-Spn1 transposase 2081638 6217948 SPCG_2090 Streptococcus pneumoniae CGSP14 IS1380-Spn1 transposase YP_001836807.1 2080292 D 516950 CDS YP_001836808.1 182685061 6218234 complement(2081974..2082825) 1 NC_010582.1 transcriptional regulator MutR 2082825 6218234 SPCG_2091 Streptococcus pneumoniae CGSP14 transcriptional regulator MutR YP_001836808.1 2081974 R 516950 CDS YP_001836809.1 182685062 6217962 complement(2082800..2082934) 1 NC_010582.1 hypothetical protein 2082934 6217962 SPCG_2092 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836809.1 2082800 R 516950 CDS YP_001836810.1 182685063 6217517 2082949..2083290 1 NC_010582.1 hypothetical protein 2083290 6217517 SPCG_2093 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836810.1 2082949 D 516950 CDS YP_001836811.1 182685064 6217949 2083354..2083518 1 NC_010582.1 histidyl-tRNA synthetase 2083518 6217949 SPCG_2094 Streptococcus pneumoniae CGSP14 histidyl-tRNA synthetase YP_001836811.1 2083354 D 516950 CDS YP_001836812.1 182685065 6217841 complement(2083544..2085247) 1 NC_010582.1 catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis; dihydroxy-acid dehydratase 2085247 ilvD 6217841 ilvD Streptococcus pneumoniae CGSP14 dihydroxy-acid dehydratase YP_001836812.1 2083544 R 516950 CDS YP_001836813.1 182685066 6217235 complement(2085480..2086412) 1 NC_010582.1 transketolase, C-terminal subunit 2086412 tktC 6217235 tktC Streptococcus pneumoniae CGSP14 transketolase, C-terminal subunit YP_001836813.1 2085480 R 516950 CDS YP_001836814.1 182685067 6217603 complement(2086409..2087266) 1 NC_010582.1 transketolase 2087266 tktN 6217603 tktN Streptococcus pneumoniae CGSP14 transketolase YP_001836814.1 2086409 R 516950 CDS YP_001836815.1 182685068 6217761 complement(2087270..2088616) 1 NC_010582.1 membrane component; functions with enzymes IIB (sgaB; ulaB) and IIA (sgaA; ulaC) enzyme I and HPr for anaerobic utilization and uptake of L-ascorbate; sgaTBA are regulated by yifQ as well as Crp and Fnr; PTS system ascorbate-specific transporter subunit IIC 2088616 ulaA 6217761 ulaA Streptococcus pneumoniae CGSP14 PTS system ascorbate-specific transporter subunit IIC YP_001836815.1 2087270 R 516950 CDS YP_001836816.1 182685069 6218207 complement(2088629..2088913) 1 NC_010582.1 PTS system transporter subunit IIB 2088913 6218207 SPCG_2099 Streptococcus pneumoniae CGSP14 PTS system transporter subunit IIB YP_001836816.1 2088629 R 516950 CDS YP_001836817.1 182685070 6217496 complement(2088917..2090947) 1 NC_010582.1 BglG family transcriptional regulator 2090947 6217496 SPCG_2100 Streptococcus pneumoniae CGSP14 BglG family transcriptional regulator YP_001836817.1 2088917 R 516950 CDS YP_001836818.1 182685071 6218009 2091138..2092145 1 NC_010582.1 hypothetical protein 2092145 6218009 SPCG_2101 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836818.1 2091138 D 516950 CDS YP_001836819.1 182685072 6216496 2092148..2092348 1 NC_010582.1 hypothetical protein 2092348 6216496 SPCG_2102 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836819.1 2092148 D 516950 CDS YP_001836820.1 182685073 6217514 2092500..2092682 1 NC_010582.1 some L32 proteins have zinc finger motifs consisting of CXXC while others do not; 50S ribosomal protein L32 2092682 rpmF 6217514 rpmF Streptococcus pneumoniae CGSP14 50S ribosomal protein L32 YP_001836820.1 2092500 D 516950 CDS YP_001836821.1 182685074 6216850 2092698..2092847 1 NC_010582.1 in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif; 50S ribosomal protein L33 2092847 rpmG 6216850 rpmG Streptococcus pneumoniae CGSP14 50S ribosomal protein L33 YP_001836821.1 2092698 D 516950 CDS YP_001836822.1 182685075 6216902 complement(2093339..2095324) 1 NC_010582.1 choline binding protein PcpA 2095324 pcpA 6216902 pcpA Streptococcus pneumoniae CGSP14 choline binding protein PcpA YP_001836822.1 2093339 R 516950 CDS YP_001836823.1 182685076 6217076 2095659..2095841 1 NC_010582.1 degenerate transposase 2095841 6217076 SPCG_2106 Streptococcus pneumoniae CGSP14 degenerate transposase YP_001836823.1 2095659 D 516950 CDS YP_001836824.1 182685077 6217265 2095912..2096229 1 NC_010582.1 degenerate transposase 2096229 6217265 SPCG_2107 Streptococcus pneumoniae CGSP14 degenerate transposase YP_001836824.1 2095912 D 516950 CDS YP_001836825.1 182685078 6216516 2096234..2096497 1 NC_010582.1 degenerate transposase 2096497 6216516 SPCG_2108 Streptococcus pneumoniae CGSP14 degenerate transposase YP_001836825.1 2096234 D 516950 CDS YP_001836826.1 182685079 6216903 complement(2096567..2096893) 1 NC_010582.1 hypothetical protein 2096893 6216903 SPCG_2109 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836826.1 2096567 R 516950 CDS YP_001836827.1 182685080 6216573 2097128..2097223 1 NC_010582.1 hypothetical protein 2097223 6216573 SPCG_2110 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836827.1 2097128 D 516950 CDS YP_001836828.1 182685081 6218425 complement(2097307..2099187) 1 NC_010582.1 glycosyl hydrolase-like protein 2099187 6218425 SPCG_2111 Streptococcus pneumoniae CGSP14 glycosyl hydrolase-like protein YP_001836828.1 2097307 R 516950 CDS YP_001836829.1 182685082 6216551 complement(2099181..2100062) 1 NC_010582.1 ROK family protein 2100062 6216551 SPCG_2112 Streptococcus pneumoniae CGSP14 ROK family protein YP_001836829.1 2099181 R 516950 CDS YP_001836830.1 182685083 6216444 complement(2100134..2102794) 1 NC_010582.1 hypothetical protein 2102794 6216444 SPCG_2113 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836830.1 2100134 R 516950 CDS YP_001836831.1 182685085 6216747 complement(2102870..2104174) 1 NC_010582.1 hypothetical protein 2104174 6216747 SPCG_2114 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836831.1 2102870 R 516950 CDS YP_001836832.1 182685084 6216582 2104152..2104247 1 NC_010582.1 hypothetical protein 2104247 6216582 SPCG_2115 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836832.1 2104152 D 516950 CDS YP_001836833.1 182685086 6217090 2104321..2106405 1 NC_010582.1 cell wall antigen 2106405 6217090 SPCG_2116 Streptococcus pneumoniae CGSP14 cell wall antigen YP_001836833.1 2104321 D 516950 CDS YP_001836834.1 182685087 6216813 complement(2106445..2108196) 1 NC_010582.1 hypothetical protein 2108196 6216813 SPCG_2117 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836834.1 2106445 R 516950 CDS YP_001836835.1 182685088 6216736 2108880..2110109 1 NC_010582.1 catalyzes the degradation of arginine to citruline and ammonia; arginine deiminase 2110109 6216736 SPCG_2118 Streptococcus pneumoniae CGSP14 arginine deiminase YP_001836835.1 2108880 D 516950 CDS YP_001836836.1 182685089 6216904 2110167..2111183 1 NC_010582.1 catalyzes the formation of ornithine and carbamylphosphate from citrulline in the arginine catabolic pathway; ornithine carbamoyltransferase 2111183 arcB 6216904 arcB Streptococcus pneumoniae CGSP14 ornithine carbamoyltransferase YP_001836836.1 2110167 D 516950 CDS YP_001836837.1 182685090 6217899 2111348..2112295 1 NC_010582.1 catalyzes the reversible synthesis of carbamate and ATP from carbamoyl phosphate and ADP; carbamate kinase 2112295 arcC 6217899 arcC Streptococcus pneumoniae CGSP14 carbamate kinase YP_001836837.1 2111348 D 516950 CDS YP_001836838.1 182685091 6216814 2112506..2114017 1 NC_010582.1 hypothetical protein 2114017 6216814 SPCG_2121 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836838.1 2112506 D 516950 CDS YP_001836839.1 182685092 6216547 2114039..2115370 1 NC_010582.1 hypothetical protein 2115370 6216547 SPCG_2122 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836839.1 2114039 D 516950 CDS YP_001836840.1 182685093 6216702 complement(2115978..2116244) 1 NC_010582.1 hypothetical protein 2116244 6216702 SPCG_2123 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836840.1 2115978 R 516950 CDS YP_001836841.1 182685094 6216558 complement(2116583..2117482) 1 NC_010582.1 hypothetical protein 2117482 6216558 SPCG_2124 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836841.1 2116583 R 516950 CDS YP_001836842.1 182685095 6217174 complement(2117612..2118763) 1 NC_010582.1 iron-containing alcohol dehydrogenase 2118763 adh2 6217174 adh2 Streptococcus pneumoniae CGSP14 iron-containing alcohol dehydrogenase YP_001836842.1 2117612 R 516950 CDS YP_001836843.1 182685096 6216773 complement(2118909..2120675) 1 NC_010582.1 catalyzes the conversion of the aldose L-fucose into the corresponding ketose L-fuculose; L-fucose isomerase 2120675 fucI 6216773 fucI Streptococcus pneumoniae CGSP14 L-fucose isomerase YP_001836843.1 2118909 R 516950 CDS YP_001836844.1 182685097 6216613 complement(2120688..2121416) 1 NC_010582.1 L-fuculose phosphate aldolase 2121416 fucA 6216613 fucA Streptococcus pneumoniae CGSP14 L-fuculose phosphate aldolase YP_001836844.1 2120688 R 516950 CDS YP_001836845.1 182685098 6216570 complement(2121431..2124517) 1 NC_010582.1 hypothetical protein 2124517 6216570 SPCG_2128 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836845.1 2121431 R 516950 CDS YP_001836846.1 182685099 6216946 complement(2124459..2126675) 1 NC_010582.1 alpha-galactosidase 2126675 6216946 SPCG_2129 Streptococcus pneumoniae CGSP14 alpha-galactosidase YP_001836846.1 2124459 R 516950 CDS YP_001836847.1 182685100 6216759 complement(2126697..2128568) 1 NC_010582.1 hypothetical protein 2128568 6216759 SPCG_2130 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836847.1 2126697 R 516950 CDS YP_001836848.1 182685101 6216758 complement(2128574..2129893) 1 NC_010582.1 glycosyl hydrolase 2129893 6216758 SPCG_2131 Streptococcus pneumoniae CGSP14 glycosyl hydrolase YP_001836848.1 2128574 R 516950 CDS YP_001836849.1 182685102 6216719 complement(2129890..2130735) 1 NC_010582.1 sugar ABC transporter permease 2130735 6216719 SPCG_2132 Streptococcus pneumoniae CGSP14 sugar ABC transporter permease YP_001836849.1 2129890 R 516950 CDS YP_001836850.1 182685103 6217510 complement(2130732..2131718) 1 NC_010582.1 sugar ABC transporter permease 2131718 6217510 SPCG_2133 Streptococcus pneumoniae CGSP14 sugar ABC transporter permease YP_001836850.1 2130732 R 516950 CDS YP_001836851.1 182685104 6218137 complement(2131748..2133040) 1 NC_010582.1 sugar ABC transporter substrate-binding protein 2133040 6218137 SPCG_2134 Streptococcus pneumoniae CGSP14 sugar ABC transporter substrate-binding protein YP_001836851.1 2131748 R 516950 CDS YP_001836852.1 182685105 6217443 complement(2133069..2134517) 1 NC_010582.1 L-fuculose kinase fucK 2134517 fucK 6217443 fucK Streptococcus pneumoniae CGSP14 L-fuculose kinase fucK YP_001836852.1 2133069 R 516950 CDS YP_001836853.1 182685106 6217194 2134648..2135421 1 NC_010582.1 fucose operon repressor 2135421 fcsR 6217194 fcsR Streptococcus pneumoniae CGSP14 fucose operon repressor YP_001836853.1 2134648 D 516950 CDS YP_001836854.1 182685107 6217119 complement(2136592..2138097) 1 NC_010582.1 zinc ABC transporter zinc-binding lipoprotein 2138097 6217119 SPCG_2137 Streptococcus pneumoniae CGSP14 zinc ABC transporter zinc-binding lipoprotein YP_001836854.1 2136592 R 516950 CDS YP_001836855.1 182685108 6218238 complement(2138107..2138937) 1 NC_010582.1 zinc ABC transporter permease 2138937 6218238 SPCG_2138 Streptococcus pneumoniae CGSP14 zinc ABC transporter permease YP_001836855.1 2138107 R 516950 CDS YP_001836856.1 182685109 6217760 complement(2138906..2139610) 1 NC_010582.1 zinc ABC transporter ATP-binding protein 2139610 6217760 SPCG_2139 Streptococcus pneumoniae CGSP14 zinc ABC transporter ATP-binding protein YP_001836856.1 2138906 R 516950 CDS YP_001836857.1 182685110 6218479 complement(2139610..2140110) 1 NC_010582.1 adc operon repressor AdcR 2140110 adcR 6218479 adcR Streptococcus pneumoniae CGSP14 adc operon repressor AdcR YP_001836857.1 2139610 R 516950 CDS YP_001836858.1 182685111 6218393 complement(2140205..2141488) 1 NC_010582.1 dltD protein 2141488 dltD 6218393 dltD Streptococcus pneumoniae CGSP14 dltD protein YP_001836858.1 2140205 R 516950 CDS YP_001836859.1 182685112 6217361 complement(2141466..2141705) 1 NC_010582.1 D-alanyl carrier protein subunit; involved in the incorporation of D-alanine into membrane-associated D-alanyl-lipoteichoic acid; D-alanyl carrier protein is the acceptor of activated D-alanine which it donates to a membrane acceptor(D-alanyl transferase) for incorporation into membrane lipoteichoic acid; D-alanine--poly(phosphoribitol) ligase subunit 2 2141705 dltC 6217361 dltC Streptococcus pneumoniae CGSP14 D-alanine--poly(phosphoribitol) ligase subunit 2 YP_001836859.1 2141466 R 516950 CDS YP_001836860.1 182685113 6218408 complement(2141719..2142963) 1 NC_010582.1 dltB protein 2142963 dltB 6218408 dltB Streptococcus pneumoniae CGSP14 dltB protein YP_001836860.1 2141719 R 516950 CDS YP_001836861.1 182685114 6217792 complement(2142960..2144690) 1 NC_010582.1 transfers D-alanine to the D-alanyl carrier protein during the incorporation of D-alanine into lipoteichoic acid; D-alanine--poly(phosphoribitol) ligase subunit 1 2144690 dltA 6217792 dltA Streptococcus pneumoniae CGSP14 D-alanine--poly(phosphoribitol) ligase subunit 1 YP_001836861.1 2142960 R 516950 CDS YP_001836862.1 182685115 6217688 complement(2144711..2144845) 1 NC_010582.1 hypothetical protein 2144845 6217688 SPCG_2145 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836862.1 2144711 R 516950 CDS YP_001836863.1 182685116 6217635 complement(2145156..2146334) 1 NC_010582.1 hypothetical protein 2146334 6217635 SPCG_2146 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836863.1 2145156 R 516950 CDS YP_001836864.1 182685117 6217315 complement(2146794..2147786) 1 NC_010582.1 hypothetical protein 2147786 6217315 SPCG_2147 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836864.1 2146794 R 516950 CDS YP_001836865.1 182685118 6218035 complement(2147790..2148071) 1 NC_010582.1 hypothetical protein 2148071 6218035 SPCG_2148 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836865.1 2147790 R 516950 CDS YP_001836866.1 182685119 6216601 2149111..2149770 1 NC_010582.1 hypothetical protein 2149770 6216601 SPCG_2149 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836866.1 2149111 D 516950 CDS YP_001836867.1 182685120 6216686 complement(2149857..2150060) 1 NC_010582.1 hypothetical protein 2150060 6216686 SPCG_2150 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836867.1 2149857 R 516950 CDS YP_001836868.1 182685121 6217675 2150153..2150254 1 NC_010582.1 hypothetical protein 2150254 6217675 SPCG_2151 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836868.1 2150153 D 516950 CDS YP_001836869.1 182685122 6218218 complement(2150251..2151009) 1 NC_010582.1 glycerol uptake facilitator protein 2151009 glpF 6218218 glpF Streptococcus pneumoniae CGSP14 glycerol uptake facilitator protein YP_001836869.1 2150251 R 516950 CDS YP_001836870.1 182685123 6216356 complement(2151025..2152851) 1 NC_010582.1 hypothetical protein 2152851 6216356 SPCG_2153 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836870.1 2151025 R 516950 CDS YP_001836871.1 182685124 6217304 complement(2152893..2154401) 1 NC_010582.1 Converts glycerol and ADP to glycerol-3-phosphate and ADP; glycerol kinase 2154401 glpK 6217304 glpK Streptococcus pneumoniae CGSP14 glycerol kinase YP_001836871.1 2152893 R 516950 CDS YP_001836872.1 182685125 6216963 complement(2154560..2155987) 1 NC_010582.1 hypothetical protein 2155987 6216963 SPCG_2155 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836872.1 2154560 R 516950 CDS YP_001836873.1 182685126 6218041 2156152..2157024 1 NC_010582.1 becomes active under oxidative stress; four conserved cysteines bind a zinc atom when they are in the reduced state and the enzyme is inactive; oxidative stress results in oxidized cysteines, release of zinc, and binding of Hsp33 to aggregation-prone proteins; forms dimers and higher order oligomers; Hsp33-like chaperonin 2157024 hslO 6218041 hslO Streptococcus pneumoniae CGSP14 Hsp33-like chaperonin YP_001836873.1 2156152 D 516950 CDS YP_001836874.1 182685127 6217539 2156981..2157991 1 NC_010582.1 NifR3 family TIM-barrel protein 2157991 6217539 SPCG_2157 Streptococcus pneumoniae CGSP14 NifR3 family TIM-barrel protein YP_001836874.1 2156981 D 516950 CDS YP_001836875.1 182685128 6217403 complement(2158221..2160383) 1 NC_010582.1 choline binding protein A 2160383 pspC 6217403 pspC Streptococcus pneumoniae CGSP14 choline binding protein A YP_001836875.1 2158221 R 516950 CDS YP_001836876.1 182685129 6216574 complement(2160462..2160989) 1 NC_010582.1 hypothetical protein 2160989 6216574 SPCG_2159 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836876.1 2160462 R 516950 CDS YP_001836877.1 182685130 6216704 complement(2161084..2162415) 1 NC_010582.1 sensor histidine kinase 2162415 6216704 SPCG_2160 Streptococcus pneumoniae CGSP14 sensor histidine kinase YP_001836877.1 2161084 R 516950 CDS YP_001836878.1 182685131 6217291 complement(2162412..2163065) 1 NC_010582.1 DNA-binding response regulator 2163065 6217291 SPCG_2161 Streptococcus pneumoniae CGSP14 DNA-binding response regulator YP_001836878.1 2162412 R 516950 CDS YP_001836879.1 182685132 6217220 complement(2163707..2166139) 1 NC_010582.1 ATP-dependent Clp protease, ATP-binding subunit 2166139 6217220 SPCG_2162 Streptococcus pneumoniae CGSP14 ATP-dependent Clp protease, ATP-binding subunit YP_001836879.1 2163707 R 516950 CDS YP_001836880.1 182685133 6216561 complement(2166141..2166662) 1 NC_010582.1 CtsR family transcriptional regulator 2166662 ctsR 6216561 ctsR Streptococcus pneumoniae CGSP14 CtsR family transcriptional regulator YP_001836880.1 2166141 R 516950 CDS YP_001836881.1 182685134 6216862 complement(2166718..2167446) 1 NC_010582.1 ABC transporter ATP-binding protein 2167446 6216862 SPCG_2164 Streptococcus pneumoniae CGSP14 ABC transporter ATP-binding protein YP_001836881.1 2166718 R 516950 CDS YP_001836882.1 182685135 6216856 complement(2167446..2168453) 1 NC_010582.1 ABC transporter substrate-binding protein 2168453 6216856 SPCG_2165 Streptococcus pneumoniae CGSP14 ABC transporter substrate-binding protein YP_001836882.1 2167446 R 516950 CDS YP_001836883.1 182685136 6217086 complement(2168492..2169241) 1 NC_010582.1 ABC transporter permease 2169241 6217086 SPCG_2166 Streptococcus pneumoniae CGSP14 ABC transporter permease YP_001836883.1 2168492 R 516950 CDS YP_001836884.1 182685137 6217906 complement(2169213..2169503) 1 NC_010582.1 hypothetical protein 2169503 6217906 SPCG_2167 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836884.1 2169213 R 516950 CDS YP_001836885.1 182685138 6217546 complement(2169759..2171105) 1 NC_010582.1 choline binding protein D 2171105 cbpD 6217546 cbpD Streptococcus pneumoniae CGSP14 choline binding protein D YP_001836885.1 2169759 R 516950 CDS YP_001836886.1 182685139 6217678 complement(2171194..2171460) 1 NC_010582.1 hypothetical protein 2171460 6217678 SPCG_2169 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836886.1 2171194 R 516950 CDS YP_001836887.1 182685140 6216638 complement(2171462..2172814) 1 NC_010582.1 unwinds double stranded DNA; replicative DNA helicase 2172814 dnaC 6216638 dnaC Streptococcus pneumoniae CGSP14 replicative DNA helicase YP_001836887.1 2171462 R 516950 CDS YP_001836888.1 182685141 6217234 complement(2172858..2173310) 1 NC_010582.1 in Escherichia coli this protein is wrapped around the base of the L1 stalk; 50S ribosomal protein L9 2173310 rplI 6217234 rplI Streptococcus pneumoniae CGSP14 50S ribosomal protein L9 YP_001836888.1 2172858 R 516950 CDS YP_001836889.1 182685142 6217986 complement(2173307..2175280) 1 NC_010582.1 DHH subfamily 1 protein 2175280 6217986 SPCG_2172 Streptococcus pneumoniae CGSP14 DHH subfamily 1 protein YP_001836889.1 2173307 R 516950 CDS YP_001836890.1 182685143 6217408 complement(2175416..2175964) 1 NC_010582.1 ribosomal subunit interface protein 2175964 6217408 SPCG_2173 Streptococcus pneumoniae CGSP14 ribosomal subunit interface protein YP_001836890.1 2175416 R 516950 CDS YP_001836891.1 182685144 6218048 complement(2176044..2176706) 1 NC_010582.1 competence protein ComF 2176706 comFC 6218048 comFC Streptococcus pneumoniae CGSP14 competence protein ComF YP_001836891.1 2176044 R 516950 CDS YP_001836892.1 182685145 6217509 complement(2176703..2178001) 1 NC_010582.1 helicase 2178001 comFA 6217509 comFA Streptococcus pneumoniae CGSP14 helicase YP_001836892.1 2176703 R 516950 CDS YP_001836893.1 182685146 6218213 2178057..2178692 1 NC_010582.1 hypothetical protein 2178692 6218213 SPCG_2176 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836893.1 2178057 D 516950 CDS YP_001836894.1 182685147 6218245 2178977..2179897 1 NC_010582.1 cysteine synthase 2179897 cycK 6218245 cycK Streptococcus pneumoniae CGSP14 cysteine synthase YP_001836894.1 2178977 D 516950 CDS YP_001836895.1 182685148 6217032 complement(2180094..2180492) 1 NC_010582.1 transposase 2180492 6217032 SPCG_2178 Streptococcus pneumoniae CGSP14 transposase YP_001836895.1 2180094 R 516950 CDS YP_001836896.1 182685149 6217464 complement(2180932..2181255) 1 NC_010582.1 IS66 family Orf2 2181255 6217464 SPCG_2179 Streptococcus pneumoniae CGSP14 IS66 family Orf2 YP_001836896.1 2180932 R 516950 CDS YP_001836897.1 182685150 6218252 complement(2181501..2182541) 1 NC_010582.1 EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu; elongation factor Ts 2182541 tsf 6218252 tsf Streptococcus pneumoniae CGSP14 elongation factor Ts YP_001836897.1 2181501 R 516950 CDS YP_001836898.2 408767007 6217821 complement(2182620..2183399) 1 NC_010582.1 one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit; 30S ribosomal protein S2 2183399 rpsB 6217821 rpsB Streptococcus pneumoniae CGSP14 30S ribosomal protein S2 YP_001836898.2 2182620 R 516950 CDS YP_001836899.1 182685152 6217667 complement(2183622..2184800) 1 NC_010582.1 secreted 45 kd protein 2184800 6217667 SPCG_2182 Streptococcus pneumoniae CGSP14 secreted 45 kd protein YP_001836899.1 2183622 R 516950 CDS YP_001836900.1 182685153 6217605 complement(2184894..2185388) 1 NC_010582.1 rod shpae-determining protein MreD 2185388 mreD 6217605 mreD Streptococcus pneumoniae CGSP14 rod shpae-determining protein MreD YP_001836900.1 2184894 R 516950 CDS YP_001836901.1 182685154 6217977 complement(2185388..2186206) 1 NC_010582.1 in some organisms this protein is a transmembrane protein while in others it is periplasmic; involved in some organisms with other components of the MreBCD complex and with penicillin binding proteins in the periplasm or cell wall; rod shape-determining protein MreC 2186206 mreC 6217977 mreC Streptococcus pneumoniae CGSP14 rod shape-determining protein MreC YP_001836901.1 2185388 R 516950 CDS YP_001836902.1 182685155 6217511 complement(2186265..2187059) 1 NC_010582.1 hypothetical protein 2187059 6217511 SPCG_2185 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836902.1 2186265 R 516950 CDS YP_001836903.1 182685156 6217261 complement(2187052..2187891) 1 NC_010582.1 with CbiNQ forms the ABC transporter for cobalt import; Streptococcus has two adjacent copies of this gene; cobalt transporter ATP-binding subunit 2187891 cbiO 6217261 cbiO Streptococcus pneumoniae CGSP14 cobalt transporter ATP-binding subunit YP_001836903.1 2187052 R 516950 CDS YP_001836904.1 182685157 6217302 complement(2187876..2188703) 1 NC_010582.1 with CbiNQ forms the ABC transporter for cobalt import; Streptococcus has two adjacent copies of this gene; cobalt transporter ATP-binding subunit 2188703 cbiO 6217302 cbiO Streptococcus pneumoniae CGSP14 cobalt transporter ATP-binding subunit YP_001836904.1 2187876 R 516950 CDS YP_001836905.1 182685158 6217458 complement(2188700..2189245) 1 NC_010582.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase 2189245 6217458 SPCG_2188 Streptococcus pneumoniae CGSP14 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase YP_001836905.1 2188700 R 516950 CDS YP_001836906.1 182685159 6217982 complement(2189256..2190086) 1 NC_010582.1 hypothetical protein 2190086 6217982 SPCG_2189 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836906.1 2189256 R 516950 CDS YP_001836907.1 182685160 6217568 complement(2190119..2191402) 1 NC_010582.1 M16 family peptidase 2191402 6217568 SPCG_2190 Streptococcus pneumoniae CGSP14 M16 family peptidase YP_001836907.1 2190119 R 516950 CDS YP_001836908.1 182685161 6217582 complement(2191399..2192649) 1 NC_010582.1 hypothetical protein 2192649 6217582 SPCG_2191 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836908.1 2191399 R 516950 CDS YP_001836909.1 182685162 6217940 2192808..2193176 1 NC_010582.1 hypothetical protein 2193176 6217940 SPCG_2192 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836909.1 2192808 D 516950 CDS YP_001836910.1 182685163 6217553 2193179..2194276 1 NC_010582.1 Required for DNA replication; binds preferentially to single-stranded, linear DNA; recombination protein F 2194276 recF 6217553 recF Streptococcus pneumoniae CGSP14 recombination protein F YP_001836910.1 2193179 D 516950 CDS YP_001836911.1 182685164 6216353 complement(2194327..2195805) 1 NC_010582.1 catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate; inosine 5'-monophosphate dehydrogenase 2195805 imdH 6216353 imdH Streptococcus pneumoniae CGSP14 inosine 5'-monophosphate dehydrogenase YP_001836911.1 2194327 R 516950 CDS YP_001836912.1 182685165 6218219 complement(2195957..2196982) 1 NC_010582.1 catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; tryptophanyl-tRNA synthetase II 2196982 trpS 6218219 trpS Streptococcus pneumoniae CGSP14 tryptophanyl-tRNA synthetase II YP_001836912.1 2195957 R 516950 CDS YP_001836913.1 182685166 6217782 2197188..2198810 1 NC_010582.1 ABC transporter ATP-binding protein 2198810 6217782 SPCG_2196 Streptococcus pneumoniae CGSP14 ABC transporter ATP-binding protein YP_001836913.1 2197188 D 516950 CDS YP_001836914.1 182685167 6218069 2198872..2201424 1 NC_010582.1 ABC transporter permease 2201424 6218069 SPCG_2197 Streptococcus pneumoniae CGSP14 ABC transporter permease YP_001836914.1 2198872 D 516950 CDS YP_001836915.1 182685168 6217083 complement(2201867..2202205) 1 NC_010582.1 hypothetical protein 2202205 6217083 SPCG_2198 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836915.1 2201867 R 516950 CDS YP_001836916.1 182685169 6217065 complement(2202290..2203057) 1 NC_010582.1 hypothetical protein 2203057 6217065 SPCG_2199 Streptococcus pneumoniae CGSP14 hypothetical protein YP_001836916.1 2202290 R 516950 CDS YP_001836917.1 182685170 6217221 2203236..2203778 1 NC_010582.1 TetR family transcriptional regulator 2203778 6217221 SPCG_2200 Streptococcus pneumoniae CGSP14 TetR family transcriptional regulator YP_001836917.1 2203236 D 516950 CDS YP_001836918.1 182685171 6217951 complement(2204021..2204773) 1 NC_010582.1 response regulator ComE 2204773 comE 6217951 comE Streptococcus pneumoniae CGSP14 response regulator ComE YP_001836918.1 2204021 R 516950 CDS YP_001836919.1 182685172 6218300 complement(2204770..2206095) 1 NC_010582.1 sensor histidine kinase ComD 2206095 comD 6218300 comD Streptococcus pneumoniae CGSP14 sensor histidine kinase ComD YP_001836919.1 2204770 R 516950 CDS YP_001836920.1 182685173 6217427 complement(2206116..2206241) 1 NC_010582.1 competence stimulating peptide 2 2206241 comC 6217427 comC Streptococcus pneumoniae CGSP14 competence stimulating peptide 2 YP_001836920.1 2206116 R 516950 CDS YP_001836921.1 182685174 6217067 complement(2206523..2207002) 1 NC_010582.1 SPOUT methyltransferase family protein; crystal structure shows homodimer; in Escherichia coli this protein methylates pseudouridine at position 1915 of the 23S ribosomal RNA; rRNA large subunit methyltransferase 2207002 6217067 SPCG_2204 Streptococcus pneumoniae CGSP14 rRNA large subunit methyltransferase YP_001836921.1 2206523 R 516950 CDS YP_001836922.1 182685175 6217643 2207173..2208366 1 NC_010582.1 serine protease 2208366 sphtra 6217643 sphtra Streptococcus pneumoniae CGSP14 serine protease YP_001836922.1 2207173 D 516950 CDS YP_001836923.1 182685176 6217478 2208424..2209182 1 NC_010582.1 spoJ protein 2209182 spo0J 6217478 spo0J Streptococcus pneumoniae CGSP14 spoJ protein YP_001836923.1 2208424 D 516950 CDS