-- dump date 20140620_084543 -- class Genbank::CDS -- table cds -- table main -- field 1 id -- field 2 GI -- field 3 GeneID -- field 4 chrom_position -- field 5 chromosome -- field 6 codon_start -- field 7 contig -- field 8 description -- field 9 end_pos -- field 10 gene -- field 11 gene_id -- field 12 name -- field 13 organism -- field 14 product -- field 15 protein_id -- field 16 start_pos -- field 17 strand -- field 18 taxid -- field 19 type -- header -- id GI GeneID chrom_position chromosome codon_start contig description end_pos gene gene_id name organism product protein_id start_pos strand taxid type YP_002036722.1 194398133 6479623 197..1558 1 NC_011072.1 binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication; can also affect transcription of multiple genes including itself.; chromosomal replication initiation protein 1558 dnaA 6479623 dnaA Streptococcus pneumoniae G54 chromosomal replication initiation protein YP_002036722.1 197 D 512566 CDS YP_002036723.1 194397554 6480778 1717..2853 1 NC_011072.1 binds the polymerase to DNA and acts as a sliding clamp; DNA polymerase III subunit beta 2853 dnaN 6480778 dnaN Streptococcus pneumoniae G54 DNA polymerase III subunit beta YP_002036723.1 1717 D 512566 CDS YP_002036724.1 194396943 6479471 2918..3112 1 NC_011072.1 identified by match to protein family HMM PF06107; hypothetical protein 3112 6479471 SPG_0003 Streptococcus pneumoniae G54 hypothetical protein YP_002036724.1 2918 D 512566 CDS YP_002036725.1 194398291 6479709 3196..4311 1 NC_011072.1 translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1; GTP-dependent nucleic acid-binding protein EngD 4311 6479709 SPG_0004 Streptococcus pneumoniae G54 GTP-dependent nucleic acid-binding protein EngD YP_002036725.1 3196 D 512566 CDS YP_002036726.1 194397946 6479159 4382..4951 1 NC_011072.1 Enables the recycling of peptidyl-tRNAs produced at termination of translation; peptidyl-tRNA hydrolase 4951 pth 6479159 pth Streptococcus pneumoniae G54 peptidyl-tRNA hydrolase YP_002036726.1 4382 D 512566 CDS YP_002036727.1 194397105 6479186 4952..8461 1 NC_011072.1 identified by match to protein family HMM PF00270; match to protein family HMM PF00271; match to protein family HMM PF02559; match to protein family HMM PF03461; match to protein family HMM PF04851; match to protein family HMM TIGR00580; transcription-repair coupling factor 8461 mfd 6479186 mfd Streptococcus pneumoniae G54 transcription-repair coupling factor YP_002036727.1 4952 D 512566 CDS YP_002036728.1 194396770 6479927 8519..8785 1 NC_011072.1 identified by match to protein family HMM PF01479; S4 domain 8785 6479927 SPG_0007 Streptococcus pneumoniae G54 S4 domain YP_002036728.1 8519 D 512566 CDS YP_002036729.1 194398092 6479742 8778..9146 1 NC_011072.1 identified by match to protein family HMM PF04977; septum formation initiator 9146 6479742 SPG_0008 Streptococcus pneumoniae G54 septum formation initiator YP_002036729.1 8778 D 512566 CDS YP_002036730.1 194397494 6479659 9151..9273 1 NC_011072.1 hypothetical protein 9273 6479659 SPG_0009 Streptococcus pneumoniae G54 hypothetical protein YP_002036730.1 9151 D 512566 CDS YP_002036731.1 194396993 6480346 9266..10534 1 NC_011072.1 hypothetical protein 10534 6480346 SPG_0010 Streptococcus pneumoniae G54 hypothetical protein YP_002036731.1 9266 D 512566 CDS YP_002036732.1 194398531 6480232 10531..11808 1 NC_011072.1 identified by match to protein family HMM PF01171; match to protein family HMM TIGR02432; match to protein family HMM TIGR02433; tRNA(Ile)-lysidine synthase 11808 tilS 6480232 tilS Streptococcus pneumoniae G54 tRNA(Ile)-lysidine synthase YP_002036732.1 10531 D 512566 CDS YP_002036733.1 194397408 6480008 11812..12354 1 NC_011072.1 identified by match to protein family HMM PF00156; match to protein family HMM TIGR01203; hypoxanthine-guanine phosphoribosyltransferase 12354 hpt 6480008 hpt Streptococcus pneumoniae G54 hypoxanthine-guanine phosphoribosyltransferase YP_002036733.1 11812 D 512566 CDS YP_002036734.1 194396790 6480187 12370..14328 1 NC_011072.1 identified by match to protein family HMM PF00004; match to protein family HMM PF01434; match to protein family HMM PF06480; match to protein family HMM TIGR01241; cell division protein FtsH 14328 6480187 SPG_0013 Streptococcus pneumoniae G54 cell division protein FtsH YP_002036734.1 12370 D 512566 CDS YP_002036735.1 194396660 6480223 14450..14929 1 NC_011072.1 transcriptional regulator ComX1 14929 6480223 SPG_0014 Streptococcus pneumoniae G54 transcriptional regulator ComX1 YP_002036735.1 14450 D 512566 CDS YP_002036736.1 194398170 6480113 complement(20407..20724) 1 NC_011072.1 IS1167 transposase 20724 6480113 SPG_0021 Streptococcus pneumoniae G54 IS1167 transposase YP_002036736.1 20407 R 512566 CDS YP_002036737.1 194397264 6480207 complement(20757..20900) 1 NC_011072.1 IS1167 transposase 20900 6480207 SPG_0022 Streptococcus pneumoniae G54 IS1167 transposase YP_002036737.1 20757 R 512566 CDS YP_002036738.1 194397472 6479125 complement(20948..21154) 1 NC_011072.1 IS1167 transposase 21154 6479125 SPG_0023 Streptococcus pneumoniae G54 IS1167 transposase YP_002036738.1 20948 R 512566 CDS YP_002036739.1 194396996 6479635 21470..21706 1 NC_011072.1 identified by glimmer; putative; hypothetical protein 21706 6479635 SPG_0024 Streptococcus pneumoniae G54 hypothetical protein YP_002036739.1 21470 D 512566 CDS YP_002036740.1 194397970 6479952 21895..23223 1 NC_011072.1 catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis; adenylosuccinate synthetase 23223 purA 6479952 purA Streptococcus pneumoniae G54 adenylosuccinate synthetase YP_002036740.1 21895 D 512566 CDS YP_002036741.1 194398441 6478825 23424..23744 1 NC_011072.1 contains potential frameshift; identified by match to protein family HMM PF00383; cytosine/adenosine deaminase 23744 6478825 SPG_0026 Streptococcus pneumoniae G54 cytosine/adenosine deaminase YP_002036741.1 23424 D 512566 CDS YP_002036742.1 194396984 6479762 23710..23826 1 NC_011072.1 contains potential frameshift; cytosine/adenosine deaminase 23826 6479762 SPG_0027 Streptococcus pneumoniae G54 cytosine/adenosine deaminase YP_002036742.1 23710 D 512566 CDS YP_002036743.1 194397504 6479988 24077..24520 1 NC_011072.1 catalyzes the formation of dUMP from dUTP; deoxyuridine 5'-triphosphate nucleotidohydrolase 24520 dut 6479988 dut Streptococcus pneumoniae G54 deoxyuridine 5'-triphosphate nucleotidohydrolase YP_002036743.1 24077 D 512566 CDS YP_002036744.1 194398233 6479002 24480..25037 1 NC_011072.1 identified by match to protein family HMM PF00300; phosphoglycerate mutase family protein 25037 6479002 SPG_0029 Streptococcus pneumoniae G54 phosphoglycerate mutase family protein YP_002036744.1 24480 D 512566 CDS YP_002036745.1 194397801 6479294 25150..26412 1 NC_011072.1 Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents; DNA repair protein RadA 26412 radA 6479294 radA Streptococcus pneumoniae G54 DNA repair protein RadA YP_002036745.1 25150 D 512566 CDS YP_002036746.1 194398261 6480370 26485..26982 1 NC_011072.1 identified by match to protein family HMM PF00484; hypothetical protein 26982 6480370 SPG_0031 Streptococcus pneumoniae G54 hypothetical protein YP_002036746.1 26485 D 512566 CDS YP_002036747.1 194396909 6479579 27007..27537 1 NC_011072.1 contains potential frameshift; hypothetical protein 27537 6479579 SPG_0032 Streptococcus pneumoniae G54 hypothetical protein YP_002036747.1 27007 D 512566 CDS YP_002036748.1 194397367 6480066 27530..27661 1 NC_011072.1 contains potential frameshift; hypothetical protein 27661 6480066 SPG_0033 Streptococcus pneumoniae G54 hypothetical protein YP_002036748.1 27530 D 512566 CDS YP_002036749.1 194398096 6480158 27806..28774 1 NC_011072.1 catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP; ribose-phosphate pyrophosphokinase 28774 prs1 6480158 prs1 Streptococcus pneumoniae G54 ribose-phosphate pyrophosphokinase YP_002036749.1 27806 D 512566 CDS YP_002036750.1 194397482 6480480 complement(29315..29548) 1 NC_011072.1 hypothetical protein 29548 6480480 SPG_0035 Streptococcus pneumoniae G54 hypothetical protein YP_002036750.1 29315 R 512566 CDS YP_002036751.1 194398208 6479882 complement(29541..29657) 1 NC_011072.1 identified by glimmer; putative; hypothetical protein 29657 6479882 SPG_0036 Streptococcus pneumoniae G54 hypothetical protein YP_002036751.1 29541 R 512566 CDS YP_002036752.1 194398646 6478774 complement(29872..30186) 1 NC_011072.1 hypothetical protein 30186 6478774 SPG_0037 Streptococcus pneumoniae G54 hypothetical protein YP_002036752.1 29872 R 512566 CDS YP_002036753.1 194397391 6479502 30478..33111 1 NC_011072.1 has 3'-5' exonuclease, 5'-3' exonuclease and 5'-3'polymerase activities, primarily functions to fill gaps during DNA replication and repair; DNA polymerase I 33111 polA 6479502 polA Streptococcus pneumoniae G54 DNA polymerase I YP_002036753.1 30478 D 512566 CDS YP_002036754.1 194397723 6480801 33196..33633 1 NC_011072.1 identified by glimmer; putative; hypothetical protein 33633 6480801 SPG_0039 Streptococcus pneumoniae G54 hypothetical protein YP_002036754.1 33196 D 512566 CDS YP_002036755.1 194398373 6480199 complement(33816..34826) 1 NC_011072.1 identified by match to protein family HMM PF03601; hypothetical protein 34826 6480199 SPG_0040 Streptococcus pneumoniae G54 hypothetical protein YP_002036755.1 33816 R 512566 CDS YP_002036756.1 194397097 6478850 34975..36144 1 NC_011072.1 catalyzes the transamination of the aromatic amino acid forming a ketoacid; first step in aromatic amino acid degradation in lactococci; aromatic amino acid aminotransferase 36144 6478850 SPG_0041 Streptococcus pneumoniae G54 aromatic amino acid aminotransferase YP_002036756.1 34975 D 512566 CDS YP_002036757.1 194397697 6480494 36141..36911 1 NC_011072.1 involved in DNA repair and RecFOR pathway recombination; RecFOR proteins displace ssDNA-binding protein and facilitate the production of RecA-coated ssDNA; DNA repair protein RecO 36911 recO 6480494 recO Streptococcus pneumoniae G54 DNA repair protein RecO YP_002036757.1 36141 D 512566 CDS YP_002036758.1 194398054 6479529 36908..37900 1 NC_011072.1 involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsY; putative glycerol-3-phosphate acyltransferase PlsX 37900 6479529 SPG_0043 Streptococcus pneumoniae G54 putative glycerol-3-phosphate acyltransferase PlsX YP_002036758.1 36908 D 512566 CDS YP_002036759.1 194396801 6478663 37906..38139 1 NC_011072.1 acyl carrier protein 38139 6478663 SPG_0044 Streptococcus pneumoniae G54 acyl carrier protein YP_002036759.1 37906 D 512566 CDS YP_002036760.1 194397052 6479113 38182..38475 1 NC_011072.1 transposase 38475 6479113 SPG_0045 Streptococcus pneumoniae G54 transposase YP_002036760.1 38182 D 512566 CDS YP_002036761.1 194398595 6479931 38678..38908 1 NC_011072.1 identified by match to protein family HMM TIGR01847; hypothetical protein 38908 6479931 SPG_0046 Streptococcus pneumoniae G54 hypothetical protein YP_002036761.1 38678 D 512566 CDS YP_002036762.1 194397990 6479323 38911..39036 1 NC_011072.1 identified by glimmer; putative; hypothetical protein 39036 6479323 SPG_0047 Streptococcus pneumoniae G54 hypothetical protein YP_002036762.1 38911 D 512566 CDS YP_002036763.1 194397308 6479211 39623..41776 1 NC_011072.1 identified by match to protein family HMM PF00005; match to protein family HMM PF00664; match to protein family HMM PF03412; match to protein family HMM TIGR01193; transport/processing ATP-binding protein ComA 41776 comA 6479211 comA Streptococcus pneumoniae G54 transport/processing ATP-binding protein ComA YP_002036763.1 39623 D 512566 CDS YP_002036764.1 194398598 6479544 41789..43138 1 NC_011072.1 identified by match to protein family HMM TIGR01000; competence factor transport protein ComB 43138 comB 6479544 comB Streptococcus pneumoniae G54 competence factor transport protein ComB YP_002036764.1 41789 D 512566 CDS YP_002036765.1 194398384 6479608 43308..44015 1 NC_011072.1 catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis; SAICAR synthase; phosphoribosylaminoimidazole-succinocarboxamide synthase 44015 purC 6479608 purC Streptococcus pneumoniae G54 phosphoribosylaminoimidazole-succinocarboxamide synthase YP_002036765.1 43308 D 512566 CDS YP_002036766.1 194397931 6479310 44072..47797 1 NC_011072.1 identified by match to protein family HMM PF02769; match to protein family HMM TIGR01857; phosphoribosylformylglycinamide synthetase 47797 purL 6479310 purL Streptococcus pneumoniae G54 phosphoribosylformylglycinamide synthetase YP_002036766.1 44072 D 512566 CDS YP_002036767.1 194397123 6478668 47890..49332 1 NC_011072.1 Catalyzes first step of the de novo purine nucleotide biosynthetic pathway; amidophosphoribosyltransferase 49332 purF 6478668 purF Streptococcus pneumoniae G54 amidophosphoribosyltransferase YP_002036767.1 47890 D 512566 CDS YP_002036768.1 194398379 6480229 49369..50391 1 NC_011072.1 catalyzes the formation of 1-(5-phosphoribosyl)-5-aminoimidazole from 2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in purine biosynthesis; phosphoribosylaminoimidazole synthetase 50391 purM 6480229 purM Streptococcus pneumoniae G54 phosphoribosylaminoimidazole synthetase YP_002036768.1 49369 D 512566 CDS YP_002036769.1 194398070 6478742 50388..50933 1 NC_011072.1 glycinamide ribonucleotide transformylase; GAR Tfase; catalyzes the synthesis of 5'-phosphoribosylformylglycinamide from 5'-phosphoribosylglycinamide and 10-formyltetrahydrofolate; PurN requires formyl folate for the reaction unlike PurT which uses formate; phosphoribosylglycinamide formyltransferase 50933 purN 6478742 purN Streptococcus pneumoniae G54 phosphoribosylglycinamide formyltransferase YP_002036769.1 50388 D 512566 CDS YP_002036770.1 194396879 6479163 51017..51526 1 NC_011072.1 identified by match to protein family HMM PF04892; hypothetical protein 51526 6479163 SPG_0055 Streptococcus pneumoniae G54 hypothetical protein YP_002036770.1 51017 D 512566 CDS YP_002036771.1 194396916 6479017 51551..53098 1 NC_011072.1 involved in de novo purine biosynthesis; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 53098 purH 6479017 purH Streptococcus pneumoniae G54 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase YP_002036771.1 51551 D 512566 CDS YP_002036772.1 194398590 6480009 53220..54482 1 NC_011072.1 catalyzes the formation of N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-D-ribosylamine and glycine in purine biosynthesis; phosphoribosylamine--glycine ligase 54482 purD 6480009 purD Streptococcus pneumoniae G54 phosphoribosylamine--glycine ligase YP_002036772.1 53220 D 512566 CDS YP_002036773.1 194398140 6479555 54885..55373 1 NC_011072.1 identified by match to protein family HMM PF00731; match to protein family HMM TIGR01162; phosphoribosylaminoimidazole carboxylase catalytic subunit 55373 purE 6479555 purE Streptococcus pneumoniae G54 phosphoribosylaminoimidazole carboxylase catalytic subunit YP_002036773.1 54885 D 512566 CDS YP_002036774.1 194397662 6480634 55360..56451 1 NC_011072.1 With PurE catalyzes the conversion of aminoimidazole ribonucleotide to carboxyaminoimidazole ribonucleotide in the de novo purine nucleotide biosynthetic pathway; phosphoribosylaminoimidazole carboxylase ATPase subunit 56451 purK 6480634 purK Streptococcus pneumoniae G54 phosphoribosylaminoimidazole carboxylase ATPase subunit YP_002036774.1 55360 D 512566 CDS YP_002036775.1 194396905 6479567 56461..56688 1 NC_011072.1 identified by glimmer; putative; hypothetical protein 56688 6479567 SPG_0060 Streptococcus pneumoniae G54 hypothetical protein YP_002036775.1 56461 D 512566 CDS YP_002036776.1 194398324 6479736 56751..58049 1 NC_011072.1 Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide; adenylosuccinate lyase 58049 purB 6479736 purB Streptococcus pneumoniae G54 adenylosuccinate lyase YP_002036776.1 56751 D 512566 CDS YP_002036777.1 194398622 6478652 complement(58104..62042) 1 NC_011072.1 identified by match to protein family HMM PF00728; match to protein family HMM PF00746; match to protein family HMM PF04650; match to protein family HMM PF07501; match to protein family HMM TIGR01167; match to protein family HMM TIGR01168; beta-N-acetylhexosaminidase 62042 6478652 SPG_0062 Streptococcus pneumoniae G54 beta-N-acetylhexosaminidase YP_002036777.1 58104 R 512566 CDS YP_002036778.1 194397376 6479531 complement(62357..63100) 1 NC_011072.1 identified by match to protein family HMM PF00392; match to protein family HMM PF07702; GntR family transcriptional regulator 63100 6479531 SPG_0063 Streptococcus pneumoniae G54 GntR family transcriptional regulator YP_002036778.1 62357 R 512566 CDS YP_002036779.1 194397614 6479805 63421..65208 1 NC_011072.1 identified by match to protein family HMM PF01301; match to protein family HMM PF02449; beta-galactosidase 65208 6479805 SPG_0064 Streptococcus pneumoniae G54 beta-galactosidase YP_002036779.1 63421 D 512566 CDS YP_002036780.1 194398074 6478829 65205..65681 1 NC_011072.1 identified by match to protein family HMM PF03830; PTS system transporter subunit IIB 65681 6478829 SPG_0065 Streptococcus pneumoniae G54 PTS system transporter subunit IIB YP_002036780.1 65205 D 512566 CDS YP_002036781.1 194398754 6479467 65709..66614 1 NC_011072.1 identified by match to protein family HMM PF03609; PTS system transporter subunit IIC 66614 6479467 SPG_0066 Streptococcus pneumoniae G54 PTS system transporter subunit IIC YP_002036781.1 65709 D 512566 CDS YP_002036782.1 194397103 6480744 66601..67416 1 NC_011072.1 identified by match to protein family HMM PF03613; PTS system transporter subunit IID 67416 6480744 SPG_0067 Streptococcus pneumoniae G54 PTS system transporter subunit IID YP_002036782.1 66601 D 512566 CDS YP_002036783.1 194397885 6480096 67423..67827 1 NC_011072.1 identified by match to protein family HMM PF03610; PTS system transporter subunit IIA 67827 6480096 SPG_0068 Streptococcus pneumoniae G54 PTS system transporter subunit IIA YP_002036783.1 67423 D 512566 CDS YP_002036784.1 194396654 6480037 68126..69292 1 NC_011072.1 identified by match to protein family HMM PF01380; putative AgaS family sugar isomerase 69292 6480037 SPG_0069 Streptococcus pneumoniae G54 putative AgaS family sugar isomerase YP_002036784.1 68126 D 512566 CDS YP_002036785.1 194397234 6480193 69408..70445 1 NC_011072.1 identified by match to protein family HMM PF01263; aldose-1-epimerase 70445 6480193 SPG_0070 Streptococcus pneumoniae G54 aldose-1-epimerase YP_002036785.1 69408 D 512566 CDS YP_002036786.1 194397832 6480168 70607..71119 1 NC_011072.1 hypothetical protein 71119 6480168 SPG_0071 Streptococcus pneumoniae G54 hypothetical protein YP_002036786.1 70607 D 512566 CDS YP_002036787.1 194398738 6480667 71140..71775 1 NC_011072.1 identified by match to protein family HMM PF01473; choline binding protein I 71775 cbpI 6480667 cbpI Streptococcus pneumoniae G54 choline binding protein I YP_002036787.1 71140 D 512566 CDS YP_002036788.1 194398709 6479116 complement(71778..71894) 1 NC_011072.1 identified by glimmer; putative; hypothetical protein 71894 6479116 SPG_0073 Streptococcus pneumoniae G54 hypothetical protein YP_002036788.1 71778 R 512566 CDS YP_002036789.1 194396933 6479482 72227..77797 1 NC_011072.1 identified by match to protein family HMM PF05342; match to protein family HMM PF07501; match to protein family HMM PF07580; match to protein family HMM PF07581; zinc metalloprotease ZmpC 77797 zmpC 6479482 zmpC Streptococcus pneumoniae G54 zinc metalloprotease ZmpC YP_002036789.1 72227 D 512566 CDS YP_002036790.1 194396979 6479719 77900..78013 1 NC_011072.1 hypothetical protein 78013 6479719 SPG_0075 Streptococcus pneumoniae G54 hypothetical protein YP_002036790.1 77900 D 512566 CDS YP_002036791.1 194398408 6480099 78153..79007 1 NC_011072.1 identified by match to protein family HMM PF00903; hypothetical protein 79007 6480099 SPG_0076 Streptococcus pneumoniae G54 hypothetical protein YP_002036791.1 78153 D 512566 CDS YP_002036792.1 194398236 6480769 79113..79670 1 NC_011072.1 acetyltransferase 79670 6480769 SPG_0077 Streptococcus pneumoniae G54 acetyltransferase YP_002036792.1 79113 D 512566 CDS YP_002036793.1 194397470 6478871 79887..80651 1 NC_011072.1 identified by match to protein family HMM PF01048; phosphorylase, Pnp/Udp family protein 80651 6478871 SPG_0078 Streptococcus pneumoniae G54 phosphorylase, Pnp/Udp family protein YP_002036793.1 79887 D 512566 CDS YP_002036794.1 194397672 6480024 81264..82643 1 NC_011072.1 identified by match to protein family HMM PF02386; potassium uptake protein, Trk family protein 82643 6480024 SPG_0079 Streptococcus pneumoniae G54 potassium uptake protein, Trk family protein YP_002036794.1 81264 D 512566 CDS YP_002036795.1 194397069 6479606 82657..83322 1 NC_011072.1 identified by match to protein family HMM PF02254; Trk transporter NAD+ binding protein 83322 6479606 SPG_0080 Streptococcus pneumoniae G54 Trk transporter NAD+ binding protein YP_002036795.1 82657 D 512566 CDS YP_002036796.1 194396713 6479638 83677..83850 1 NC_011072.1 family 2 glycosyl transferase 83850 6479638 SPG_0081 Streptococcus pneumoniae G54 family 2 glycosyl transferase YP_002036796.1 83677 D 512566 CDS YP_002036797.1 194398490 6480144 83917..84327 1 NC_011072.1 family 2 glycosyl transferase 84327 6480144 SPG_0082 Streptococcus pneumoniae G54 family 2 glycosyl transferase YP_002036797.1 83917 D 512566 CDS YP_002036798.1 194397775 6480367 84443..86104 1 NC_011072.1 identified by match to protein family HMM PF00746; match to protein family HMM PF04650; match to protein family HMM TIGR01167; match to protein family HMM TIGR01168; cell wall surface anchor family protein 86104 6480367 SPG_0083 Streptococcus pneumoniae G54 cell wall surface anchor family protein YP_002036798.1 84443 D 512566 CDS YP_002036799.1 194397353 6480528 86271..86969 1 NC_011072.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00486; response regulator 86969 6480528 SPG_0084 Streptococcus pneumoniae G54 response regulator YP_002036799.1 86271 D 512566 CDS YP_002036800.1 194396888 6479985 86966..88018 1 NC_011072.1 identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518; histidine kinase 88018 6479985 SPG_0085 Streptococcus pneumoniae G54 histidine kinase YP_002036800.1 86966 D 512566 CDS YP_002036801.1 194398306 6479014 88213..88824 1 NC_011072.1 primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination; 30S ribosomal protein S4 88824 rpsD 6479014 rpsD Streptococcus pneumoniae G54 30S ribosomal protein S4 YP_002036801.1 88213 D 512566 CDS YP_002036802.1 194397289 6479394 89564..89824 1 NC_011072.1 identified by glimmer; putative; hypothetical protein 89824 6479394 SPG_0087 Streptococcus pneumoniae G54 hypothetical protein YP_002036802.1 89564 D 512566 CDS YP_002036803.1 194397277 6478751 89778..89999 1 NC_011072.1 hypothetical protein 89999 6478751 SPG_0088 Streptococcus pneumoniae G54 hypothetical protein YP_002036803.1 89778 D 512566 CDS YP_002036804.1 194396701 6479019 90318..91247 1 NC_011072.1 identified by match to protein family HMM PF00528; ABC transporter permease 91247 6479019 SPG_0089 Streptococcus pneumoniae G54 ABC transporter permease YP_002036804.1 90318 D 512566 CDS YP_002036805.1 194398505 6479641 91261..92184 1 NC_011072.1 identified by match to protein family HMM PF00528; ABC transporter permease 92184 6479641 SPG_0090 Streptococcus pneumoniae G54 ABC transporter permease YP_002036805.1 91261 D 512566 CDS YP_002036806.1 194397543 6480720 92394..93869 1 NC_011072.1 identified by match to protein family HMM PF01547; ABC transporter substrate-binding protein 93869 6480720 SPG_0091 Streptococcus pneumoniae G54 ABC transporter substrate-binding protein YP_002036806.1 92394 D 512566 CDS YP_002036807.1 194398717 6479563 94141..95127 1 NC_011072.1 identified by glimmer; putative; hypothetical protein 95127 6479563 SPG_0092 Streptococcus pneumoniae G54 hypothetical protein YP_002036807.1 94141 D 512566 CDS YP_002036808.1 194398179 6478807 95249..96109 1 NC_011072.1 hypothetical protein 96109 6478807 SPG_0093 Streptococcus pneumoniae G54 hypothetical protein YP_002036808.1 95249 D 512566 CDS YP_002036809.1 194397510 6480519 complement(96181..97245) 1 NC_011072.1 identified by glimmer; putative; hypothetical protein 97245 6480519 SPG_0094 Streptococcus pneumoniae G54 hypothetical protein YP_002036809.1 96181 R 512566 CDS YP_002036810.1 194397864 6479233 complement(97308..98219) 1 NC_011072.1 hypothetical protein 98219 6479233 SPG_0095 Streptococcus pneumoniae G54 hypothetical protein YP_002036810.1 97308 R 512566 CDS YP_002036811.1 194398303 6480632 complement(98212..98805) 1 NC_011072.1 hypothetical protein 98805 6480632 SPG_0096 Streptococcus pneumoniae G54 hypothetical protein YP_002036811.1 98212 R 512566 CDS YP_002036812.1 194396874 6479573 complement(98792..99118) 1 NC_011072.1 identified by match to protein family HMM PF03551; PadR family transcriptional regulator 99118 6479573 SPG_0097 Streptococcus pneumoniae G54 PadR family transcriptional regulator YP_002036812.1 98792 R 512566 CDS YP_002036813.1 194396777 6478762 complement(99257..100423) 1 NC_011072.1 identified by match to protein family HMM PF07690; transporter 100423 6478762 SPG_0098 Streptococcus pneumoniae G54 transporter YP_002036813.1 99257 R 512566 CDS YP_002036814.1 194397410 6479774 100574..101638 1 NC_011072.1 identified by match to protein family HMM PF00535; glycosyl transferase 101638 6479774 SPG_0099 Streptococcus pneumoniae G54 glycosyl transferase YP_002036814.1 100574 D 512566 CDS YP_002036815.1 194398751 6480189 101680..103530 1 NC_011072.1 identified by match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF02719; match to protein family HMM PF04321; match to protein family HMM PF07993; capsular polysaccharide biosynthesis protein 103530 6480189 SPG_0100 Streptococcus pneumoniae G54 capsular polysaccharide biosynthesis protein YP_002036815.1 101680 D 512566 CDS YP_002036816.1 194397982 6479246 complement(103925..104557) 1 NC_011072.1 identified by match to protein family HMM PF00702; match to protein family HMM TIGR01549; haloacid dehalogenase-like hydrolase 104557 6479246 SPG_0101 Streptococcus pneumoniae G54 haloacid dehalogenase-like hydrolase YP_002036816.1 103925 R 512566 CDS YP_002036817.1 194398391 6479316 complement(104579..105451) 1 NC_011072.1 identified by match to protein family HMM PF03313; match to protein family HMM TIGR00718; L-serine dehydratase subunit alpha 105451 sdhA 6479316 sdhA Streptococcus pneumoniae G54 L-serine dehydratase subunit alpha YP_002036817.1 104579 R 512566 CDS YP_002036818.1 194397086 6478802 complement(105460..106131) 1 NC_011072.1 identified by match to protein family HMM PF01842; match to protein family HMM PF03315; match to protein family HMM TIGR00719; L-serine dehydratase subunit alpha 106131 sdhB 6478802 sdhB Streptococcus pneumoniae G54 L-serine dehydratase subunit alpha YP_002036818.1 105460 R 512566 CDS YP_002036819.1 194398499 6479851 106372..106959 1 NC_011072.1 identified by match to protein family HMM PF01476; LysM domain-containing protein 106959 6479851 SPG_0104 Streptococcus pneumoniae G54 LysM domain-containing protein YP_002036819.1 106372 D 512566 CDS YP_002036820.1 194398015 6480658 108094..110202 1 NC_011072.1 identified by match to protein family HMM TIGR01654; ABC transporter membrane-spanning permease 110202 6480658 SPG_0105 Streptococcus pneumoniae G54 ABC transporter membrane-spanning permease YP_002036820.1 108094 D 512566 CDS YP_002036821.1 194397690 6479272 110199..110840 1 NC_011072.1 identified by match to protein family HMM PF00005; match to protein family HMM TIGR03608; ABC transporter ATP-binding protein 110840 6479272 SPG_0106 Streptococcus pneumoniae G54 ABC transporter ATP-binding protein YP_002036821.1 110199 D 512566 CDS YP_002036822.1 194397217 6479257 111047..111853 1 NC_011072.1 identified by match to protein family HMM PF00497; ABC transporter substrate-binding protein 111853 6479257 SPG_0107 Streptococcus pneumoniae G54 ABC transporter substrate-binding protein YP_002036822.1 111047 D 512566 CDS YP_002036823.1 194398639 6480574 111870..112289 1 NC_011072.1 identified by match to protein family HMM PF00764; argininosuccinate synthase 112289 argG 6480574 argG Streptococcus pneumoniae G54 argininosuccinate synthase YP_002036823.1 111870 D 512566 CDS YP_002036824.1 194398200 6478959 complement(112577..112897) 1 NC_011072.1 hypothetical protein 112897 6478959 SPG_0109 Streptococcus pneumoniae G54 hypothetical protein YP_002036824.1 112577 R 512566 CDS YP_002036825.1 194397915 6478778 113661..114014 1 NC_011072.1 hypothetical protein 114014 6478778 SPG_0110 Streptococcus pneumoniae G54 hypothetical protein YP_002036825.1 113661 D 512566 CDS YP_002036826.1 194397560 6478875 114011..114739 1 NC_011072.1 identified by glimmer; putative; hypothetical protein 114739 6478875 SPG_0111 Streptococcus pneumoniae G54 hypothetical protein YP_002036826.1 114011 D 512566 CDS YP_002036827.1 194396647 6479312 114893..115105 1 NC_011072.1 hypothetical protein 115105 6479312 SPG_0112 Streptococcus pneumoniae G54 hypothetical protein YP_002036827.1 114893 D 512566 CDS YP_002036828.1 194397581 6479900 115479..115604 1 NC_011072.1 hypothetical protein 115604 6479900 SPG_0113 Streptococcus pneumoniae G54 hypothetical protein YP_002036828.1 115479 D 512566 CDS YP_002036829.1 194397809 6478986 115987..117045 1 NC_011072.1 hypothetical protein 117045 6478986 SPG_0114 Streptococcus pneumoniae G54 hypothetical protein YP_002036829.1 115987 D 512566 CDS YP_002036830.1 194398289 6480203 117359..118333 1 NC_011072.1 hypothetical protein 118333 6480203 SPG_0115 Streptococcus pneumoniae G54 hypothetical protein YP_002036830.1 117359 D 512566 CDS YP_002036831.1 194397312 6479157 118807..119181 1 NC_011072.1 hypothetical protein 119181 6479157 SPG_0116 Streptococcus pneumoniae G54 hypothetical protein YP_002036831.1 118807 D 512566 CDS YP_002036832.1 194396967 6479523 119389..120291 1 NC_011072.1 hypothetical protein 120291 6479523 SPG_0117 Streptococcus pneumoniae G54 hypothetical protein YP_002036832.1 119389 D 512566 CDS YP_002036833.1 194398277 6479879 120347..120700 1 NC_011072.1 hypothetical protein 120700 6479879 SPG_0118 Streptococcus pneumoniae G54 hypothetical protein YP_002036833.1 120347 D 512566 CDS YP_002036834.1 194397940 6478707 120697..121425 1 NC_011072.1 identified by glimmer; putative; hypothetical protein 121425 6478707 SPG_0119 Streptococcus pneumoniae G54 hypothetical protein YP_002036834.1 120697 D 512566 CDS YP_002036835.1 194397068 6479490 122657..122809 1 NC_011072.1 hypothetical protein 122809 6479490 SPG_0120 Streptococcus pneumoniae G54 hypothetical protein YP_002036835.1 122657 D 512566 CDS YP_002036836.1 194396737 6480167 123363..125492 1 NC_011072.1 identified by match to protein family HMM PF01473; surface protein A 125492 pspA 6480167 pspA Streptococcus pneumoniae G54 surface protein A YP_002036836.1 123363 D 512566 CDS YP_002036837.1 194398045 6479690 125742..125870 1 NC_011072.1 identified by glimmer; putative; hypothetical protein 125870 6479690 SPG_0122 Streptococcus pneumoniae G54 hypothetical protein YP_002036837.1 125742 D 512566 CDS YP_002036838.1 194398405 6478673 125893..127014 1 NC_011072.1 catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs; tRNA-specific 2-thiouridylase MnmA 127014 mnmA 6478673 mnmA Streptococcus pneumoniae G54 tRNA-specific 2-thiouridylase MnmA YP_002036838.1 125893 D 512566 CDS YP_002036839.1 194396719 6479724 127155..127610 1 NC_011072.1 identified by match to protein family HMM PF00293; NUDIX family hydrolase 127610 6479724 SPG_0124 Streptococcus pneumoniae G54 NUDIX family hydrolase YP_002036839.1 127155 D 512566 CDS YP_002036840.1 194397114 6480060 127620..129533 1 NC_011072.1 GidA; glucose-inhibited cell division protein A; involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U) of the wobble uridine base in some tRNAs; tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA 129533 gidA 6480060 gidA Streptococcus pneumoniae G54 tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA YP_002036840.1 127620 D 512566 CDS YP_002036841.1 194398194 6479853 complement(129728..131407) 1 NC_011072.1 identified by match to protein family HMM PF00753; match to protein family HMM PF07521; match to protein family HMM TIGR00649; hypothetical protein 131407 6479853 SPG_0126 Streptococcus pneumoniae G54 hypothetical protein YP_002036841.1 129728 R 512566 CDS YP_002036842.1 194398637 6480628 complement(131409..131642) 1 NC_011072.1 identified by match to protein family HMM PF07288; hypothetical protein 131642 6480628 SPG_0127 Streptococcus pneumoniae G54 hypothetical protein YP_002036842.1 131409 R 512566 CDS YP_002036843.1 194396957 6478957 complement(132460..132612) 1 NC_011072.1 identified by match to protein family HMM TIGR01847; competence induced bacteriocin B 132612 cibB 6478957 cibB Streptococcus pneumoniae G54 competence induced bacteriocin B YP_002036843.1 132460 R 512566 CDS YP_002036844.1 194397450 6480328 complement(132614..132799) 1 NC_011072.1 Guiral PNAS 2005. 102(24):8710-8715; competence induced bacteriocin A CibA 132799 cibA 6480328 cibA Streptococcus pneumoniae G54 competence induced bacteriocin A CibA YP_002036844.1 132614 R 512566 CDS YP_002036845.1 194397265 6480504 132977..133660 1 NC_011072.1 identified by match to protein family HMM PF00814; hypothetical protein 133660 6480504 SPG_0130 Streptococcus pneumoniae G54 hypothetical protein YP_002036845.1 132977 D 512566 CDS YP_002036846.1 194397720 6479126 133657..134094 1 NC_011072.1 identified by match to protein family HMM PF00583; match to protein family HMM TIGR01575; ribosomal-protein-alanine acetyltransferase 134094 6479126 SPG_0131 Streptococcus pneumoniae G54 ribosomal-protein-alanine acetyltransferase YP_002036846.1 133657 D 512566 CDS YP_002036847.1 194398193 6480130 134084..135094 1 NC_011072.1 in most organisms, only the N-terminal domain is present in a single polypeptide; in some archaea this domain is fused to a kinase domain; this gene is essential for growth in Escherichia coli and Bacillus subtilis; the secreted glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins; the Pyrococcus structure shows DNA-binding properties, iron-binding, ATP-binding, and AP endonuclease activity; putative DNA-binding/iron metalloprotein/AP endonuclease 135094 6480130 SPG_0132 Streptococcus pneumoniae G54 putative DNA-binding/iron metalloprotein/AP endonuclease YP_002036847.1 134084 D 512566 CDS YP_002036848.1 194396781 6480627 complement(135134..135448) 1 NC_011072.1 IS1167 transposase 135448 6480627 SPG_0133 Streptococcus pneumoniae G54 IS1167 transposase YP_002036848.1 135134 R 512566 CDS YP_002036849.1 194397359 6479694 complement(135439..136416) 1 NC_011072.1 identified by match to protein family HMM PF01610; IS1167 transposase 136416 6479694 SPG_0134 Streptococcus pneumoniae G54 IS1167 transposase YP_002036849.1 135439 R 512566 CDS YP_002036850.1 194398534 6480693 137637..138191 1 NC_011072.1 contains potential frameshift; group 1 family glycosyl transferase 138191 6480693 SPG_0135 Streptococcus pneumoniae G54 group 1 family glycosyl transferase YP_002036850.1 137637 D 512566 CDS YP_002036851.1 194398526 6480285 138169..138843 1 NC_011072.1 contains potential frameshift; identified by match to protein family HMM PF00534; group 1 family glycosyl transferase 138843 6480285 SPG_0136 Streptococcus pneumoniae G54 group 1 family glycosyl transferase YP_002036851.1 138169 D 512566 CDS YP_002036852.1 194397117 6480661 138836..139708 1 NC_011072.1 identified by match to protein family HMM PF00535; group 2 family glycosyl transferase 139708 6480661 SPG_0137 Streptococcus pneumoniae G54 group 2 family glycosyl transferase YP_002036852.1 138836 D 512566 CDS YP_002036853.1 194397628 6480324 139795..141411 1 NC_011072.1 identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 141411 6480324 SPG_0138 Streptococcus pneumoniae G54 ABC transporter ATP-binding protein YP_002036853.1 139795 D 512566 CDS YP_002036854.1 194397844 6479261 142065..142847 1 NC_011072.1 identified by match to protein family HMM PF01609; IS1380-Spn1 transposase 142847 6479261 SPG_0139 Streptococcus pneumoniae G54 IS1380-Spn1 transposase YP_002036854.1 142065 D 512566 CDS YP_002036855.1 194397796 6480296 142992..143402 1 NC_011072.1 IS1380-Spn1 transposase 143402 6480296 SPG_0140 Streptococcus pneumoniae G54 IS1380-Spn1 transposase YP_002036855.1 142992 D 512566 CDS YP_002036856.1 194398285 6480724 143809..144558 1 NC_011072.1 identified by match to protein family HMM PF02585; hypothetical protein 144558 6480724 SPG_0141 Streptococcus pneumoniae G54 hypothetical protein YP_002036856.1 143809 D 512566 CDS YP_002036857.1 194397525 6479408 144571..145743 1 NC_011072.1 identified by match to protein family HMM PF00984; match to protein family HMM PF03721; match to protein family HMM TIGR03026; UDP-glucose 6-dehydrogenase 145743 6479408 SPG_0142 Streptococcus pneumoniae G54 UDP-glucose 6-dehydrogenase YP_002036857.1 144571 D 512566 CDS YP_002036858.1 194398479 6479537 146138..147001 1 NC_011072.1 identified by match to protein family HMM TIGR01716; transcriptional regulator 147001 6479537 SPG_0143 Streptococcus pneumoniae G54 transcriptional regulator YP_002036858.1 146138 D 512566 CDS YP_002036859.1 194396703 6480549 147292..147525 1 NC_011072.1 hypothetical protein 147525 6480549 SPG_0144 Streptococcus pneumoniae G54 hypothetical protein YP_002036859.1 147292 D 512566 CDS YP_002036860.1 194397280 6479980 147547..148224 1 NC_011072.1 identified by match to protein family HMM PF02517; CAAX amino terminal protease family 148224 6479980 SPG_0145 Streptococcus pneumoniae G54 CAAX amino terminal protease family YP_002036860.1 147547 D 512566 CDS YP_002036861.1 194397734 6478700 148236..148901 1 NC_011072.1 identified by match to protein family HMM PF02517; CAAX amino terminal protease family 148901 6478700 SPG_0146 Streptococcus pneumoniae G54 CAAX amino terminal protease family YP_002036861.1 148236 D 512566 CDS YP_002036862.1 194398440 6480703 148973..150199 1 NC_011072.1 hypothetical protein 150199 6480703 SPG_0147 Streptococcus pneumoniae G54 hypothetical protein YP_002036862.1 148973 D 512566 CDS YP_002036863.1 194397064 6479761 150449..151117 1 NC_011072.1 identified by match to protein family HMM PF03591; hypothetical protein 151117 6479761 SPG_0148 Streptococcus pneumoniae G54 hypothetical protein YP_002036863.1 150449 D 512566 CDS YP_002036864.1 194397208 6479823 151107..151430 1 NC_011072.1 identified by match to protein family HMM PF05437; hypothetical protein 151430 6479823 SPG_0149 Streptococcus pneumoniae G54 hypothetical protein YP_002036864.1 151107 D 512566 CDS YP_002036865.1 194398001 6480576 151534..152364 1 NC_011072.1 identified by match to protein family HMM PF00497; ABC transporter ATP-binding protein/ substrate-binding protein 152364 6480576 SPG_0150 Streptococcus pneumoniae G54 ABC transporter ATP-binding protein/ substrate-binding protein YP_002036865.1 151534 D 512566 CDS YP_002036866.1 194398677 6479227 152518..153372 1 NC_011072.1 identified by match to protein family HMM PF03180; ABC transporter substrate binding protein 153372 6479227 SPG_0151 Streptococcus pneumoniae G54 ABC transporter substrate binding protein YP_002036866.1 152518 D 512566 CDS YP_002036867.1 194398410 6479300 153472..154845 1 NC_011072.1 identified by match to protein family HMM PF01546; match to protein family HMM PF07687; M20/M25/M40 family peptidase 154845 6479300 SPG_0152 Streptococcus pneumoniae G54 M20/M25/M40 family peptidase YP_002036867.1 153472 D 512566 CDS YP_002036868.1 194397643 6480299 154838..155899 1 NC_011072.1 identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 155899 6480299 SPG_0153 Streptococcus pneumoniae G54 ABC transporter ATP-binding protein YP_002036868.1 154838 D 512566 CDS YP_002036869.1 194398350 6479209 155901..156593 1 NC_011072.1 identified by match to protein family HMM PF00528; ABC transporter permease 156593 6479209 SPG_0154 Streptococcus pneumoniae G54 ABC transporter permease YP_002036869.1 155901 D 512566 CDS YP_002036870.1 194396688 6480405 complement(156623..157192) 1 NC_011072.1 identified by match to protein family HMM TIGR02185; hypothetical protein 157192 6480405 SPG_0155 Streptococcus pneumoniae G54 hypothetical protein YP_002036870.1 156623 R 512566 CDS YP_002036871.1 194398003 6480136 157327..157941 1 NC_011072.1 identified by match to protein family HMM PF04854; hypothetical protein 157941 6480136 SPG_0156 Streptococcus pneumoniae G54 hypothetical protein YP_002036871.1 157327 D 512566 CDS YP_002036872.1 194397651 6479411 157991..159589 1 NC_011072.1 identified by match to protein family HMM PF00672; match to protein family HMM PF02518; match to protein family HMM PF06580; histidine kinase 159589 6479411 SPG_0157 Streptococcus pneumoniae G54 histidine kinase YP_002036872.1 157991 D 512566 CDS YP_002036873.1 194397433 6478817 159601..160887 1 NC_011072.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00165; response regulator 160887 6478817 SPG_0158 Streptococcus pneumoniae G54 response regulator YP_002036873.1 159601 D 512566 CDS YP_002036874.1 194396834 6480710 160939..161472 1 NC_011072.1 hypothetical protein 161472 6480710 SPG_0159 Streptococcus pneumoniae G54 hypothetical protein YP_002036874.1 160939 D 512566 CDS YP_002036875.1 194397724 6480812 161550..162020 1 NC_011072.1 has a stimulatory effect on the ribonucleotide reductase activity of NrdH with NrdEF; flavoprotein NrdI 162020 6480812 SPG_0160 Streptococcus pneumoniae G54 flavoprotein NrdI YP_002036875.1 161550 D 512566 CDS YP_002036876.1 194397394 6480172 complement(162313..163575) 1 NC_011072.1 hypothetical protein 163575 6480172 SPG_0161 Streptococcus pneumoniae G54 hypothetical protein YP_002036876.1 162313 R 512566 CDS YP_002036877.1 194397161 6480492 complement(163885..164343) 1 NC_011072.1 identified by glimmer; putative; hypothetical protein 164343 6480492 SPG_0162 Streptococcus pneumoniae G54 hypothetical protein YP_002036877.1 163885 R 512566 CDS YP_002036878.1 194397057 6479275 complement(164340..164780) 1 NC_011072.1 identified by match to protein family HMM PF04397; hypothetical protein 164780 6479275 SPG_0163 Streptococcus pneumoniae G54 hypothetical protein YP_002036878.1 164340 R 512566 CDS YP_002036879.1 194398589 6479677 164896..165075 1 NC_011072.1 hypothetical protein 165075 6479677 SPG_0164 Streptococcus pneumoniae G54 hypothetical protein YP_002036879.1 164896 D 512566 CDS YP_002036880.1 194398020 6479554 165136..167085 1 NC_011072.1 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. Promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex; DNA mismatch repair protein 167085 mutL 6479554 mutL Streptococcus pneumoniae G54 DNA mismatch repair protein YP_002036880.1 165136 D 512566 CDS YP_002036881.1 194397420 6479334 complement(167410..167877) 1 NC_011072.1 RibE; 6,7-diimethyl-8-ribityllumazine synthase; DMRL synthase; lumazine synthase; beta subunit of riboflavin synthase; condenses 5-amino-6-(1'-D)-ribityl-amino-2,4(1H,3H)-pyrimidinedione with L-3,4-dihydrohy-2-butanone-4-phosphate to generate 6,6-dimethyl-8-lumazine (DMRL); riboflavin synthase then uses 2 molecules of DMRL to produce riboflavin (vitamin B12); involved in the last steps of riboflavin biosynthesis; forms a 60mer (icosahedral shell) in both Bacillus subtilis and Escherichia coli; in Bacillus subtilis this 60mer is associated with the riboflavin synthase subunit (alpha) while in Escherichia coli it is not; 6,7-dimethyl-8-ribityllumazine synthase 167877 ribH 6479334 ribH Streptococcus pneumoniae G54 6,7-dimethyl-8-ribityllumazine synthase YP_002036881.1 167410 R 512566 CDS YP_002036882.1 194396788 6479887 complement(167878..169083) 1 NC_011072.1 identified by match to protein family HMM PF00925; match to protein family HMM PF00926; match to protein family HMM TIGR00505; match to protein family HMM TIGR00506; 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II 169083 6479887 SPG_0167 Streptococcus pneumoniae G54 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II YP_002036882.1 167878 R 512566 CDS YP_002036883.1 194398327 6480051 complement(169103..169738) 1 NC_011072.1 catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine; riboflavin synthase subunit alpha 169738 6480051 SPG_0168 Streptococcus pneumoniae G54 riboflavin synthase subunit alpha YP_002036883.1 169103 R 512566 CDS YP_002036884.1 194397666 6479495 complement(169723..170823) 1 NC_011072.1 identified by match to protein family HMM PF00383; match to protein family HMM PF01872; match to protein family HMM TIGR00227; match to protein family HMM TIGR00326; riboflavin biosynthesis protein 170823 6479495 SPG_0169 Streptococcus pneumoniae G54 riboflavin biosynthesis protein YP_002036884.1 169723 R 512566 CDS YP_002036885.1 194397075 6479374 171228..171821 1 NC_011072.1 plays an essential role in ATP-dependent branch migration of the Holliday junction; Holliday junction DNA helicase RuvA 171821 ruvA 6479374 ruvA Streptococcus pneumoniae G54 Holliday junction DNA helicase RuvA YP_002036885.1 171228 D 512566 CDS YP_002036886.1 194398537 6479654 171831..172394 1 NC_011072.1 identified by match to protein family HMM PF03352; DNA-3-methyladenine glycosylase I 172394 tag 6479654 tag Streptococcus pneumoniae G54 DNA-3-methyladenine glycosylase I YP_002036886.1 171831 D 512566 CDS YP_002036887.1 194397969 6480003 172391..173068 1 NC_011072.1 identified by match to protein family HMM PF02517; CAAX amino terminal protease family 173068 6480003 SPG_0172 Streptococcus pneumoniae G54 CAAX amino terminal protease family YP_002036887.1 172391 D 512566 CDS YP_002036888.1 194397811 6478824 complement(173205..174236) 1 NC_011072.1 identified by match to protein family HMM PF02016; MccC family protein 174236 6478824 SPG_0173 Streptococcus pneumoniae G54 MccC family protein YP_002036888.1 173205 R 512566 CDS YP_002036889.1 194397278 6480205 complement(174491..175174) 1 NC_011072.1 identified by match to protein family HMM PF06570; hypothetical protein 175174 6480205 SPG_0174 Streptococcus pneumoniae G54 hypothetical protein YP_002036889.1 174491 R 512566 CDS YP_002036890.1 194396860 6478698 complement(175186..176130) 1 NC_011072.1 identified by match to protein family HMM PF01544; CorA-like Mg2+ transporter protein 176130 6478698 SPG_0175 Streptococcus pneumoniae G54 CorA-like Mg2+ transporter protein YP_002036890.1 175186 R 512566 CDS YP_002036891.1 194398387 6479048 176262..179093 1 NC_011072.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate; excinuclease ABC subunit A 179093 uvrA 6479048 uvrA Streptococcus pneumoniae G54 excinuclease ABC subunit A YP_002036891.1 176262 D 512566 CDS YP_002036892.1 194398606 6479220 179086..180147 1 NC_011072.1 identified by match to protein family HMM PF00557; match to protein family HMM PF01321; M24 family peptidase 180147 6479220 SPG_0177 Streptococcus pneumoniae G54 M24 family peptidase YP_002036892.1 179086 D 512566 CDS YP_002036893.1 194397994 6479388 180279..180677 1 NC_011072.1 the anti-alpha factor Spx interacts with RNA polymerase alpha subunit C-terminal domain in a region that interacts with the sigma 70 subunit and may interfere with activation of promoters; in Bacillus subtilis this protein is a substrate for ClpXP protease; blocks transcription of the competence regulatory gene encoded by the srf operon; regulates a number of genes involved in thiol homeostasis including trxA and trxB; monomeric member of ArsC family of proteins; does not bind DNA; contains a disulfide bond between C10 and C13 which may sense disulfide stress; transcriptional regulator Spx 180677 spxA 6479388 spxA Streptococcus pneumoniae G54 transcriptional regulator Spx YP_002036893.1 180279 D 512566 CDS YP_002036894.1 194397658 6479196 180743..181312 1 NC_011072.1 identified by glimmer; putative; hypothetical protein 181312 6479196 SPG_0179 Streptococcus pneumoniae G54 hypothetical protein YP_002036894.1 180743 D 512566 CDS YP_002036895.1 194397095 6479574 181399..181665 1 NC_011072.1 identified by glimmer; putative; hypothetical protein 181665 6479574 SPG_0180 Streptococcus pneumoniae G54 hypothetical protein YP_002036895.1 181399 D 512566 CDS YP_002036896.1 194398342 6479840 181669..182088 1 NC_011072.1 similar to RuvC resolvase with substantial differences; NMR structural information suggests this protein is monomeric; unknown cellular function; Holliday junction resolvase-like protein 182088 6479840 SPG_0181 Streptococcus pneumoniae G54 Holliday junction resolvase-like protein YP_002036896.1 181669 D 512566 CDS YP_002036897.1 194397768 6480784 182104..182409 1 NC_011072.1 identified by match to protein family HMM PF06949; hypothetical protein 182409 6480784 SPG_0182 Streptococcus pneumoniae G54 hypothetical protein YP_002036897.1 182104 D 512566 CDS YP_002036898.1 194398301 6480339 complement(182542..182718) 1 NC_011072.1 identified by glimmer; putative; hypothetical protein 182718 6480339 SPG_0183 Streptococcus pneumoniae G54 hypothetical protein YP_002036898.1 182542 R 512566 CDS YP_002036899.1 194397996 6479571 182863..184119 1 NC_011072.1 identified by match to protein family HMM PF02875; match to protein family HMM PF08245; match to protein family HMM TIGR01499; dihydrofolate folylpolyglutamate synthetase 184119 6479571 SPG_0184 Streptococcus pneumoniae G54 dihydrofolate folylpolyglutamate synthetase YP_002036899.1 182863 D 512566 CDS YP_002036900.1 194397409 6479198 184116..184661 1 NC_011072.1 hypothetical protein 184661 6479198 SPG_0185 Streptococcus pneumoniae G54 hypothetical protein YP_002036900.1 184116 D 512566 CDS YP_002036901.1 194397295 6480188 184807..186339 1 NC_011072.1 identified by match to protein family HMM PF00614; cardiolipin synthase 186339 cls 6480188 cls Streptococcus pneumoniae G54 cardiolipin synthase YP_002036901.1 184807 D 512566 CDS YP_002036902.1 194396754 6478920 186417..186560 1 NC_011072.1 hypothetical protein 186560 6478920 SPG_0187 Streptococcus pneumoniae G54 hypothetical protein YP_002036902.1 186417 D 512566 CDS YP_002036903.1 194398472 6480313 186597..188135 1 NC_011072.1 identified by glimmer; putative; hypothetical protein 188135 6480313 SPG_0188 Streptococcus pneumoniae G54 hypothetical protein YP_002036903.1 186597 D 512566 CDS YP_002036904.1 194397878 6480612 188255..190462 1 NC_011072.1 Catalyzes the reduction of nucleoside 5'-triphosphates to 2'-deoxynucleoside 5'-triphosphates; anaerobic ribonucleoside triphosphate reductase 190462 nrdD 6480612 nrdD Streptococcus pneumoniae G54 anaerobic ribonucleoside triphosphate reductase YP_002036904.1 188255 D 512566 CDS YP_002036905.1 194397517 6480238 190474..190614 1 NC_011072.1 hypothetical protein 190614 6480238 SPG_0190 Streptococcus pneumoniae G54 hypothetical protein YP_002036905.1 190474 D 512566 CDS YP_002036906.1 194396949 6479403 190658..191164 1 NC_011072.1 identified by match to protein family HMM PF00583; GNAT family acetyltransferase 191164 6479403 SPG_0191 Streptococcus pneumoniae G54 GNAT family acetyltransferase YP_002036906.1 190658 D 512566 CDS YP_002036907.1 194398760 6480063 191157..191747 1 NC_011072.1 identified by match to protein family HMM PF04055; match to protein family HMM TIGR02491; anaerobic ribonucleoside-triphosphate reductase activating protein 191747 nrdG 6480063 nrdG Streptococcus pneumoniae G54 anaerobic ribonucleoside-triphosphate reductase activating protein YP_002036907.1 191157 D 512566 CDS YP_002036908.1 194398349 6480758 191744..192361 1 NC_011072.1 identified by glimmer; putative; hypothetical protein 192361 6480758 SPG_0193 Streptococcus pneumoniae G54 hypothetical protein YP_002036908.1 191744 D 512566 CDS YP_002036909.1 194397584 6480404 192627..192935 1 NC_011072.1 NusE; involved in assembly of the 30S subunit; in the ribosome, this protein is involved in the binding of tRNA; in Escherichia coli this protein was also found to be involved in transcription antitermination; NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination; binding of NusB/S10 to boxA nucleates assembly of the antitermination complex; 30S ribosomal protein S10 192935 rpsJ 6480404 rpsJ Streptococcus pneumoniae G54 30S ribosomal protein S10 YP_002036909.1 192627 D 512566 CDS YP_002036910.1 194397396 6479160 193151..193777 1 NC_011072.1 binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin; 50S ribosomal protein L3 193777 rplC 6479160 rplC Streptococcus pneumoniae G54 50S ribosomal protein L3 YP_002036910.1 193151 D 512566 CDS YP_002036911.1 194397434 6480532 193802..194425 1 NC_011072.1 L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA; 50S ribosomal protein L4 194425 rplD 6480532 rplD Streptococcus pneumoniae G54 50S ribosomal protein L4 YP_002036911.1 193802 D 512566 CDS YP_002036912.1 194397745 6480711 194425..194721 1 NC_011072.1 binds third domain of 23S rRNA and protein L29; part of exit tunnel; 50S ribosomal protein L23 194721 rplW 6480711 rplW Streptococcus pneumoniae G54 50S ribosomal protein L23 YP_002036912.1 194425 D 512566 CDS YP_002036913.1 194396931 6480429 194739..195572 1 NC_011072.1 one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation; 50S ribosomal protein L2 195572 rplB 6480429 rplB Streptococcus pneumoniae G54 50S ribosomal protein L2 YP_002036913.1 194739 D 512566 CDS YP_002036914.1 194396819 6479725 195676..195957 1 NC_011072.1 protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA; 30S ribosomal protein S19 195957 rpsS 6479725 rpsS Streptococcus pneumoniae G54 30S ribosomal protein S19 YP_002036914.1 195676 D 512566 CDS YP_002036915.1 194398165 6479170 195969..196313 1 NC_011072.1 binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center; 50S ribosomal protein L22 196313 rplV 6479170 rplV Streptococcus pneumoniae G54 50S ribosomal protein L22 YP_002036915.1 195969 D 512566 CDS YP_002036916.1 194398748 6480762 196326..196979 1 NC_011072.1 forms a complex with S10 and S14; binds the lower part of the 30S subunit head and the mRNA in the complete ribosome to position it for translation; 30S ribosomal protein S3 196979 rpsC 6480762 rpsC Streptococcus pneumoniae G54 30S ribosomal protein S3 YP_002036916.1 196326 D 512566 CDS YP_002036917.1 194396695 6478763 196983..197396 1 NC_011072.1 located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e; 50S ribosomal protein L16 197396 rplP 6478763 rplP Streptococcus pneumoniae G54 50S ribosomal protein L16 YP_002036917.1 196983 D 512566 CDS YP_002036918.1 194396812 6479833 197406..197612 1 NC_011072.1 one of the stabilizing components for the large ribosomal subunit; 50S ribosomal protein L29 197612 rpmC 6479833 rpmC Streptococcus pneumoniae G54 50S ribosomal protein L29 YP_002036918.1 197406 D 512566 CDS YP_002036919.1 194398616 6479352 197637..197897 1 NC_011072.1 primary binding protein; helps mediate assembly; involved in translation fidelity; 30S ribosomal protein S17 197897 rpsQ 6479352 rpsQ Streptococcus pneumoniae G54 30S ribosomal protein S17 YP_002036919.1 197637 D 512566 CDS YP_002036920.1 194398017 6479277 197923..198291 1 NC_011072.1 binds to the 23S rRNA between the centers for peptidyl transferase and GTPase; 50S ribosomal protein L14 198291 rplN 6479277 rplN Streptococcus pneumoniae G54 50S ribosomal protein L14 YP_002036920.1 197923 D 512566 CDS YP_002036921.1 194397606 6478787 198369..198674 1 NC_011072.1 assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel; 50S ribosomal protein L24 198674 rplX 6478787 rplX Streptococcus pneumoniae G54 50S ribosomal protein L24 YP_002036921.1 198369 D 512566 CDS YP_002036922.1 194397047 6479049 198698..199240 1 NC_011072.1 part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13; 50S ribosomal protein L5 199240 rplE 6479049 rplE Streptococcus pneumoniae G54 50S ribosomal protein L5 YP_002036922.1 198698 D 512566 CDS YP_002036923.1 194397784 6480224 199258..199527 1 NC_011072.1 located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group do not appear to have the zinc-binding motif; 30S ribosomal protein S14 199527 rpsN 6480224 rpsN Streptococcus pneumoniae G54 30S ribosomal protein S14 YP_002036923.1 199258 D 512566 CDS YP_002036924.1 194397190 6479964 199812..200210 1 NC_011072.1 binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; 30S ribosomal protein S8 200210 rpsH 6479964 rpsH Streptococcus pneumoniae G54 30S ribosomal protein S8 YP_002036924.1 199812 D 512566 CDS YP_002036925.1 194396863 6478745 200402..200938 1 NC_011072.1 ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance; 50S ribosomal protein L6 200938 rplF 6478745 rplF Streptococcus pneumoniae G54 50S ribosomal protein L6 YP_002036925.1 200402 D 512566 CDS YP_002036926.1 194398617 6478749 201022..201378 1 NC_011072.1 binds 5S rRNA along with protein L5 and L25; 50S ribosomal protein L18 201378 rplR 6478749 rplR Streptococcus pneumoniae G54 50S ribosomal protein L18 YP_002036926.1 201022 D 512566 CDS YP_002036927.1 194398026 6479278 201396..201890 1 NC_011072.1 located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance; 30S ribosomal protein S5 201890 rpsE 6479278 rpsE Streptococcus pneumoniae G54 30S ribosomal protein S5 YP_002036927.1 201396 D 512566 CDS YP_002036928.1 194397819 6479239 201904..202086 1 NC_011072.1 L30 binds domain II of the 23S rRNA and the 5S rRNA; similar to eukaryotic protein L7; 50S ribosomal protein L30 202086 rpmD 6479239 rpmD Streptococcus pneumoniae G54 50S ribosomal protein L30 YP_002036928.1 201904 D 512566 CDS YP_002036929.1 194397441 6480274 202231..202671 1 NC_011072.1 late assembly protein; 50S ribosomal protein L15 202671 rplO 6480274 rplO Streptococcus pneumoniae G54 50S ribosomal protein L15 YP_002036929.1 202231 D 512566 CDS YP_002036930.1 194397758 6480810 202684..203994 1 NC_011072.1 forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase; preprotein translocase subunit SecY 203994 secY 6480810 secY Streptococcus pneumoniae G54 preprotein translocase subunit SecY YP_002036930.1 202684 D 512566 CDS YP_002036931.1 194398603 6480446 204145..204783 1 NC_011072.1 essential enzyme that recycles AMP in active cells; converts ATP and AMP to two molecules of ADP; adenylate kinase 204783 adk 6480446 adk Streptococcus pneumoniae G54 adenylate kinase YP_002036931.1 204145 D 512566 CDS YP_002036932.1 194396958 6478943 204900..205118 1 NC_011072.1 stimulates the activities of the other two initiation factors, IF-2 and IF-3; translation initiation factor IF-1 205118 infA 6478943 infA Streptococcus pneumoniae G54 translation initiation factor IF-1 YP_002036932.1 204900 D 512566 CDS YP_002036933.2 408843741 6480000 <205356..205643 1 NC_011072.1 truncated; contains potential frameshift; identified by match to protein family HMM PF00416; 30S ribosomal protein S13 205643 rpsM 6480000 rpsM Streptococcus pneumoniae G54 30S ribosomal protein S13 YP_002036933.2 <205356 D 512566 CDS YP_002036934.1 194398129 6478720 205661..206044 1 NC_011072.1 located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3; 30S ribosomal protein S11 206044 rpsK 6478720 rpsK Streptococcus pneumoniae G54 30S ribosomal protein S11 YP_002036934.1 205661 D 512566 CDS YP_002036935.1 194396717 6480400 206087..207022 1 NC_011072.1 catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme; DNA-directed RNA polymerase subunit alpha 207022 rpoA 6480400 rpoA Streptococcus pneumoniae G54 DNA-directed RNA polymerase subunit alpha YP_002036935.1 206087 D 512566 CDS YP_002036936.1 194397184 6480275 207034..207420 1 NC_011072.1 is a component of the macrolide binding site in the peptidyl transferase center; 50S ribosomal protein L17 207420 rplQ 6480275 rplQ Streptococcus pneumoniae G54 50S ribosomal protein L17 YP_002036936.1 207034 D 512566 CDS YP_002036937.1 194396721 6479546 207685..207951 1 NC_011072.1 ACT domain-containing protein; hypothetical protein 207951 6479546 SPG_0222 Streptococcus pneumoniae G54 hypothetical protein YP_002036937.1 207685 D 512566 CDS YP_002036938.1 194397385 6479758 207961..209298 1 NC_011072.1 identified by match to protein family HMM PF05167; hypothetical protein 209298 6479758 SPG_0223 Streptococcus pneumoniae G54 hypothetical protein YP_002036938.1 207961 D 512566 CDS YP_002036939.1 194397872 6480558 209542..210234 1 NC_011072.1 identified by match to protein family HMM PF00300; phosphoglycerate mutase family protein 210234 6480558 SPG_0224 Streptococcus pneumoniae G54 phosphoglycerate mutase family protein YP_002036939.1 209542 D 512566 CDS YP_002036940.1 194398375 6480485 complement(210337..210750) 1 NC_011072.1 contains potential frameshift; Ulijasz AT, J Bacteriol. 2004 Dec;186(23):8123-36.; iron ABC transporter permease 210750 pitA1 6480485 pitA1 Streptococcus pneumoniae G54 iron ABC transporter permease YP_002036940.1 210337 R 512566 CDS YP_002036941.1 194397290 6478852 complement(210747..211319) 1 NC_011072.1 contains potential frameshift; Ulijasz AT, J Bacteriol. 2004 Dec;186(23):8123-36.; iron ABC transporter permease 211319 pitA2 6478852 pitA2 Streptococcus pneumoniae G54 iron ABC transporter permease YP_002036941.1 210747 R 512566 CDS YP_002036942.1 194397897 6478752 complement(211346..211714) 1 NC_011072.1 Ulijasz AT, J Bacteriol. 2004 Dec;186(23):8123-36.; iron ABC transporter permease 211714 pitD 6478752 pitD Streptococcus pneumoniae G54 iron ABC transporter permease YP_002036942.1 211346 R 512566 CDS YP_002036943.1 194398496 6478810 complement(211962..213053) 1 NC_011072.1 Ulijasz AT, J Bacteriol. 2004 Dec;186(23):8123-36.; identified by match to protein family HMM PF00005; match to protein family HMM PF08402; iron ABC transporter ATP-binding protein 213053 pitB 6478810 pitB Streptococcus pneumoniae G54 iron ABC transporter ATP-binding protein YP_002036943.1 211962 R 512566 CDS YP_002036944.1 194397480 6480763 complement(213066..213434) 1 NC_011072.1 contains potential frameshift; iron ABC transporter iron-binding protein 213434 6480763 SPG_0229 Streptococcus pneumoniae G54 iron ABC transporter iron-binding protein YP_002036944.1 213066 R 512566 CDS YP_002036945.1 194396926 6480053 complement(213579..214187) 1 NC_011072.1 contains potential frameshift; iron ABC transporter iron-binding protein 214187 6480053 SPG_0230 Streptococcus pneumoniae G54 iron ABC transporter iron-binding protein YP_002036945.1 213579 R 512566 CDS YP_002036946.1 194397572 6480278 complement(214404..214601) 1 NC_011072.1 identified by match to protein family HMM PF00165; hypothetical protein 214601 6480278 SPG_0231 Streptococcus pneumoniae G54 hypothetical protein YP_002036946.1 214404 R 512566 CDS YP_002036947.1 194398184 6478828 complement(214676..215452) 1 NC_011072.1 identified by match to protein family HMM PF04055; match to protein family HMM TIGR02494; glycyl-radical enzyme activating family protein 215452 6478828 SPG_0232 Streptococcus pneumoniae G54 glycyl-radical enzyme activating family protein YP_002036947.1 214676 R 512566 CDS YP_002036948.1 194398744 6480288 215574..216320 1 NC_011072.1 identified by match to protein family HMM PF00455; match to protein family HMM PF08220; match to protein family HMM PF08279; transcriptional regulator 216320 6480288 SPG_0233 Streptococcus pneumoniae G54 transcriptional regulator YP_002036948.1 215574 D 512566 CDS YP_002036949.1 194397183 6479214 216333..217313 1 NC_011072.1 identified by match to protein family HMM PF04198; transcriptional regulator 217313 6479214 SPG_0234 Streptococcus pneumoniae G54 transcriptional regulator YP_002036949.1 216333 D 512566 CDS YP_002036950.1 194397705 6479545 217508..217828 1 NC_011072.1 identified by match to protein family HMM PF02255; PTS system transporter subunit IIA 217828 6479545 SPG_0235 Streptococcus pneumoniae G54 PTS system transporter subunit IIA YP_002036950.1 217508 D 512566 CDS YP_002036951.1 194398477 6480355 217874..218182 1 NC_011072.1 identified by match to protein family HMM PF02302; PTS system transporter subunit IIB 218182 6480355 SPG_0236 Streptococcus pneumoniae G54 PTS system transporter subunit IIB YP_002036951.1 217874 D 512566 CDS YP_002036952.1 194397799 6480306 218199..219497 1 NC_011072.1 identified by match to protein family HMM PF02378; match to protein family HMM TIGR00410; PTS system transporter subunit IIC 219497 6480306 SPG_0237 Streptococcus pneumoniae G54 PTS system transporter subunit IIC YP_002036952.1 218199 D 512566 CDS YP_002036953.1 194398478 6479921 219648..222086 1 NC_011072.1 identified by match to protein family HMM PF01228; match to protein family HMM PF02901; match to protein family HMM TIGR01774; pyruvate formate-lyase 222086 6479921 SPG_0238 Streptococcus pneumoniae G54 pyruvate formate-lyase YP_002036953.1 219648 D 512566 CDS YP_002036954.1 194397871 6480548 222105..222773 1 NC_011072.1 similar to transaldolase from Escherichia coli; many organisms have multiple copies; fructose-6-phosphate aldolase 222773 6480548 SPG_0239 Streptococcus pneumoniae G54 fructose-6-phosphate aldolase YP_002036954.1 222105 D 512566 CDS YP_002036955.1 194397553 6480484 222791..223879 1 NC_011072.1 forms dimers and octamers; involved in conversion of glycerol to dihydroxy-acetone; glycerol dehydrogenase 223879 gldA 6480484 gldA Streptococcus pneumoniae G54 glycerol dehydrogenase YP_002036955.1 222791 D 512566 CDS YP_002036956.1 194396969 6479470 224334..226835 1 NC_011072.1 leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase; leucyl-tRNA synthetase 226835 leuS 6479470 leuS Streptococcus pneumoniae G54 leucyl-tRNA synthetase YP_002036956.1 224334 D 512566 CDS YP_002036957.1 194398752 6480171 227029..227724 1 NC_011072.1 identified by match to protein family HMM PF00583; GNAT family acetyltransferase 227724 6480171 SPG_0242 Streptococcus pneumoniae G54 GNAT family acetyltransferase YP_002036957.1 227029 D 512566 CDS YP_002036958.1 194398038 6479247 227736..228152 1 NC_011072.1 identified by match to protein family HMM PF00583; GNAT family acetyltransferase 228152 6479247 SPG_0243 Streptococcus pneumoniae G54 GNAT family acetyltransferase YP_002036958.1 227736 D 512566 CDS YP_002036959.1 194397680 6479488 229193..230191 1 NC_011072.1 promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration; Holliday junction DNA helicase RuvB 230191 ruvB 6479488 ruvB Streptococcus pneumoniae G54 Holliday junction DNA helicase RuvB YP_002036959.1 229193 D 512566 CDS YP_002036960.1 194396918 6478739 230172..230744 1 NC_011072.1 identified by match to protein family HMM PF06042; hypothetical protein 230744 6478739 SPG_0245 Streptococcus pneumoniae G54 hypothetical protein YP_002036960.1 230172 D 512566 CDS YP_002036961.1 194397226 6480231 230975..231733 1 NC_011072.1 catalyzes the formation of undecaprenyl pyrophosphate from isopentenyl pyrophosphate; undecaprenyl pyrophosphate synthase 231733 6480231 SPG_0246 Streptococcus pneumoniae G54 undecaprenyl pyrophosphate synthase YP_002036961.1 230975 D 512566 CDS YP_002036962.1 194396769 6480029 231742..232545 1 NC_011072.1 identified by match to protein family HMM PF01148; phosphatidate cytidylyltransferase 232545 cdsA 6480029 cdsA Streptococcus pneumoniae G54 phosphatidate cytidylyltransferase YP_002036962.1 231742 D 512566 CDS YP_002036963.1 194398446 6479819 232567..233826 1 NC_011072.1 identified by match to protein family HMM PF02163; match to protein family HMM TIGR00054; M50 family peptidase 233826 6479819 SPG_0248 Streptococcus pneumoniae G54 M50 family peptidase YP_002036963.1 232567 D 512566 CDS YP_002036964.1 194397930 6479978 233839..235692 1 NC_011072.1 catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro); prolyl-tRNA synthetase 235692 proS 6479978 proS Streptococcus pneumoniae G54 prolyl-tRNA synthetase YP_002036964.1 233839 D 512566 CDS YP_002036965.1 194397000 6479206 235791..237170 1 NC_011072.1 identified by match to protein family HMM PF00232; glycosyl hydrolase family protein 237170 6479206 SPG_0250 Streptococcus pneumoniae G54 glycosyl hydrolase family protein YP_002036965.1 235791 D 512566 CDS YP_002036966.1 194398402 6479949 237363..239171 1 NC_011072.1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source; glucosamine--fructose-6-phosphate aminotransferase 239171 glmS 6479949 glmS Streptococcus pneumoniae G54 glucosamine--fructose-6-phosphate aminotransferase YP_002036966.1 237363 D 512566 CDS YP_002036967.1 194398213 6479173 239290..240339 1 NC_011072.1 identified by glimmer; putative; hypothetical protein 240339 6479173 SPG_0252 Streptococcus pneumoniae G54 hypothetical protein YP_002036967.1 239290 D 512566 CDS YP_002036968.1 194397797 6478891 complement(240439..244281) 1 NC_011072.1 identified by match to protein family HMM PF00128; match to protein family HMM PF00746; match to protein family HMM PF02922; match to protein family HMM PF03714; match to protein family HMM PF04650; match to protein family HMM TIGR01167; match to protein family HMM TIGR01168; match to protein family HMM TIGR02102; alkaline amylopullulanase 244281 pulA 6478891 pulA Streptococcus pneumoniae G54 alkaline amylopullulanase YP_002036968.1 240439 R 512566 CDS YP_002036969.1 194397766 6480725 244698..245111 1 NC_011072.1 interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance; 30S ribosomal protein S12 245111 rpsL 6480725 rpsL Streptococcus pneumoniae G54 30S ribosomal protein S12 YP_002036969.1 244698 D 512566 CDS YP_002036970.1 194398272 6480217 245131..245601 1 NC_011072.1 binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit; 30S ribosomal protein S7 245601 rpsG 6480217 rpsG Streptococcus pneumoniae G54 30S ribosomal protein S7 YP_002036970.1 245131 D 512566 CDS YP_002036971.1 194398605 6479012 246026..248107 1 NC_011072.1 EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene; elongation factor G 248107 6479012 SPG_0256 Streptococcus pneumoniae G54 elongation factor G YP_002036971.1 246026 D 512566 CDS YP_002036972.1 194397447 6479387 248211..252602 1 NC_011072.1 catalyzes DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time; required for leading strand synthesis; PolC exhibits 3' to 5' exonuclease activity; DNA polymerase III PolC 252602 polC 6479387 polC Streptococcus pneumoniae G54 DNA polymerase III PolC YP_002036972.1 248211 D 512566 CDS YP_002036973.1 194398013 6480178 252704..252967 1 NC_011072.1 identified by match to protein family HMM PF04221; match to protein family HMM TIGR02384; RelB/DinJ family addiction module antitoxin 252967 6480178 SPG_0258 Streptococcus pneumoniae G54 RelB/DinJ family addiction module antitoxin YP_002036973.1 252704 D 512566 CDS YP_002036974.1 194398587 6479441 252960..253238 1 NC_011072.1 identified by match to protein family HMM PF05016; match to protein family HMM TIGR02385; RelE/StbE family addiction module toxin 253238 6479441 SPG_0259 Streptococcus pneumoniae G54 RelE/StbE family addiction module toxin YP_002036974.1 252960 D 512566 CDS YP_002036975.1 194397081 6478819 253259..253411 1 NC_011072.1 hypothetical protein 253411 6478819 SPG_0260 Streptococcus pneumoniae G54 hypothetical protein YP_002036975.1 253259 D 512566 CDS YP_002036976.1 194397269 6479820 253433..254674 1 NC_011072.1 identified by match to protein family HMM PF02073; aminopeptidase PepS 254674 6479820 SPG_0261 Streptococcus pneumoniae G54 aminopeptidase PepS YP_002036976.1 253433 D 512566 CDS YP_002036977.1 194397389 6479181 254684..254914 1 NC_011072.1 identified by match to protein family HMM PF04226; hypothetical protein 254914 6479181 SPG_0262 Streptococcus pneumoniae G54 hypothetical protein YP_002036977.1 254684 D 512566 CDS YP_002036978.1 194398298 6480799 255227..255949 1 NC_011072.1 identified by match to protein family HMM PF00849; match to protein family HMM PF01479; match to protein family HMM TIGR00093; ribosomal small subunit pseudouridine synthase A 255949 6480799 SPG_0263 Streptococcus pneumoniae G54 ribosomal small subunit pseudouridine synthase A YP_002036978.1 255227 D 512566 CDS YP_002036979.1 194398130 6479454 256166..257500 1 NC_011072.1 identified by match to protein family HMM PF03051; aminopeptidase C 257500 6479454 SPG_0264 Streptococcus pneumoniae G54 aminopeptidase C YP_002036979.1 256166 D 512566 CDS YP_002036980.1 194397532 6480401 complement(257556..258467) 1 NC_011072.1 identified by match to protein family HMM PF03613; match to protein family HMM TIGR00828; PTS system transporter subunit IID 258467 6480401 SPG_0265 Streptococcus pneumoniae G54 PTS system transporter subunit IID YP_002036980.1 257556 R 512566 CDS YP_002036981.1 194397562 6479477 complement(258491..259294) 1 NC_011072.1 identified by match to protein family HMM PF03609; PTS system transporter subunit IIC 259294 6479477 SPG_0266 Streptococcus pneumoniae G54 PTS system transporter subunit IIC YP_002036981.1 258491 R 512566 CDS YP_002036982.1 194396951 6479514 complement(259322..260311) 1 NC_011072.1 identified by match to protein family HMM PF03610; match to protein family HMM PF03830; PTS system transporter subunit IIAB 260311 6479514 SPG_0267 Streptococcus pneumoniae G54 PTS system transporter subunit IIAB YP_002036982.1 259322 R 512566 CDS YP_002036983.1 194397984 6479951 complement(260545..261564) 1 NC_011072.1 similar to zinc-dependent eukaryotic ADH enzymes and distinct from fermentative ADHs; alcohol dehydrogenase 261564 adhP 6479951 adhP Streptococcus pneumoniae G54 alcohol dehydrogenase YP_002036983.1 260545 R 512566 CDS YP_002036984.1 194397311 6478642 complement(261673..261819) 1 NC_011072.1 identified by glimmer; putative; hypothetical protein 261819 6478642 SPG_0269 Streptococcus pneumoniae G54 hypothetical protein YP_002036984.1 261673 R 512566 CDS YP_002036985.1 194398331 6478662 complement(261903..262286) 1 NC_011072.1 contains potential frameshift; identified by match to protein family HMM PF08282; hydrolase 262286 6478662 SPG_0270 Streptococcus pneumoniae G54 hydrolase YP_002036985.1 261903 R 512566 CDS YP_002036986.1 194397814 6480823 complement(262381..262716) 1 NC_011072.1 contains potential frameshift; hydrolase 262716 6480823 SPG_0271 Streptococcus pneumoniae G54 hydrolase YP_002036986.1 262381 R 512566 CDS YP_002036987.1 194397350 6480183 262906..264324 1 NC_011072.1 identified by match to protein family HMM PF00860; putative permease 264324 6480183 SPG_0272 Streptococcus pneumoniae G54 putative permease YP_002036987.1 262906 D 512566 CDS YP_002036988.1 194397390 6479755 264377..265084 1 NC_011072.1 identified by match to protein family HMM PF02517; CAAX amino terminal protease family 265084 6479755 SPG_0273 Streptococcus pneumoniae G54 CAAX amino terminal protease family YP_002036988.1 264377 D 512566 CDS YP_002036989.1 194398507 6480800 265179..266153 1 NC_011072.1 identified by match to protein family HMM PF00809; match to protein family HMM TIGR01496; dihydropteroate synthase 266153 sulA 6480800 sulA Streptococcus pneumoniae G54 dihydropteroate synthase YP_002036989.1 265179 D 512566 CDS YP_002036990.1 194396991 6480722 266155..267477 1 NC_011072.1 identified by match to protein family HMM PF02875; match to protein family HMM PF08245; match to protein family HMM TIGR01499; dihydrofolate synthetase 267477 sulB 6480722 sulB Streptococcus pneumoniae G54 dihydrofolate synthetase YP_002036990.1 266155 D 512566 CDS YP_002036991.1 194397633 6479991 267458..268012 1 NC_011072.1 involved in the first step of tetrahydrofolate biosynthesis; catalyzes the formation of formate and 2-amino-4-hydroxy-6-(erythro-1,2, 3-trihydroxypropyl)dihydropteridine triphosphate from GTP and water; forms a homopolymer; GTP cyclohydrolase I 268012 folE 6479991 folE Streptococcus pneumoniae G54 GTP cyclohydrolase I YP_002036991.1 267458 D 512566 CDS YP_002036992.1 194398210 6479597 268055..268867 1 NC_011072.1 identified by match to protein family HMM PF01288; match to protein family HMM PF02152; match to protein family HMM TIGR00525; match to protein family HMM TIGR00526; match to protein family HMM TIGR01498; bifunctional folate synthesis protein 268867 sulD 6479597 sulD Streptococcus pneumoniae G54 bifunctional folate synthesis protein YP_002036992.1 268055 D 512566 CDS YP_002036993.1 194397116 6478776 complement(268912..269229) 1 NC_011072.1 hypothetical protein 269229 6478776 SPG_0278 Streptococcus pneumoniae G54 hypothetical protein YP_002036993.1 268912 R 512566 CDS YP_002036994.1 194397648 6480085 269750..270031 1 NC_011072.1 contains potential frameshift; identified by match to protein family HMM PF00572; match to protein family HMM TIGR01066; 50S ribosomal protein L13 270031 rplM 6480085 rplM Streptococcus pneumoniae G54 50S ribosomal protein L13 YP_002036994.1 269750 D 512566 CDS YP_002036995.1 194397340 6478844 270050..270442 1 NC_011072.1 forms a direct contact with the tRNA during translation; 30S ribosomal protein S9 270442 rpsI 6478844 rpsI Streptococcus pneumoniae G54 30S ribosomal protein S9 YP_002036995.1 270050 D 512566 CDS YP_002036996.1 194397746 6480093 complement(270703..271125) 1 NC_011072.1 identified by match to protein family HMM PF00589; phage integrase family integrase/recombinase 271125 6480093 SPG_0281 Streptococcus pneumoniae G54 phage integrase family integrase/recombinase YP_002036996.1 270703 R 512566 CDS YP_002036997.1 194396842 6480716 271272..271448 1 NC_011072.1 hypothetical protein 271448 6480716 SPG_0282 Streptococcus pneumoniae G54 hypothetical protein YP_002036997.1 271272 D 512566 CDS YP_002036998.1 194397634 6478683 271849..274062 1 NC_011072.1 identified by match to protein family HMM PF01055; family 31 glycosyl hydrolase 274062 6478683 SPG_0283 Streptococcus pneumoniae G54 family 31 glycosyl hydrolase YP_002036998.1 271849 D 512566 CDS YP_002036999.1 194397315 6479598 complement(274284..274760) 1 NC_011072.1 identified by match to protein family HMM PF00255; glutathione peroxidase 274760 6479598 SPG_0284 Streptococcus pneumoniae G54 glutathione peroxidase YP_002036999.1 274284 R 512566 CDS YP_002037000.1 194396877 6479778 274983..278186 1 NC_011072.1 identified by match to protein family HMM PF00746; match to protein family HMM PF02018; match to protein family HMM PF02278; match to protein family HMM PF02884; match to protein family HMM PF08124; match to protein family HMM TIGR01167; hyaluronate lyase Hyl 278186 hyl 6479778 hyl Streptococcus pneumoniae G54 hyaluronate lyase Hyl YP_002037000.1 274983 D 512566 CDS YP_002037001.1 194397824 6479156 278802..278927 1 NC_011072.1 IS200S transposase 278927 6479156 SPG_0286 Streptococcus pneumoniae G54 IS200S transposase YP_002037001.1 278802 D 512566 CDS YP_002037002.1 194397328 6480602 complement(279303..279932) 1 NC_011072.1 catalyzes the formation of pyruvate and glyoxylate from 4-hydroxy-2-oxoglutarate; or pyruvate and D-glyceraldehyde 3-phosphate from 2-dehydro-3-deoxy-D-glyconate 6-phosphate; keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase 279932 eda 6480602 eda Streptococcus pneumoniae G54 keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase YP_002037002.1 279303 R 512566 CDS YP_002037003.1 194396885 6479924 complement(279942..280943) 1 NC_011072.1 carbohydrate kinase, PfkB family; identified by match to protein family HMM PF00294; 2-dehydro-3-deoxygluconatekinase 280943 6479924 SPG_0288 Streptococcus pneumoniae G54 2-dehydro-3-deoxygluconatekinase YP_002037003.1 279942 R 512566 CDS YP_002037004.1 194398439 6478809 complement(280974..281615) 1 NC_011072.1 identified by match to protein family HMM PF02502; hypothetical protein 281615 6478809 SPG_0289 Streptococcus pneumoniae G54 hypothetical protein YP_002037004.1 280974 R 512566 CDS YP_002037005.1 194397497 6479760 complement(281634..282449) 1 NC_011072.1 Involved in the nonphosphorylative, ketogenic oxidation of glucose and oxidizes gluconate to 5-ketogluconate; gluconate 5-dehydrogenase 282449 6479760 SPG_0290 Streptococcus pneumoniae G54 gluconate 5-dehydrogenase YP_002037005.1 281634 R 512566 CDS YP_002037006.1 194397005 6479453 282720..283148 1 NC_011072.1 identified by match to protein family HMM PF03610; PTS system transporter subunit IIA 283148 6479453 SPG_0291 Streptococcus pneumoniae G54 PTS system transporter subunit IIA YP_002037006.1 282720 D 512566 CDS YP_002037007.1 194398671 6480449 283160..284350 1 NC_011072.1 identified by match to protein family HMM PF07470; unsaturated glucuronyl hydrolase 284350 6480449 SPG_0292 Streptococcus pneumoniae G54 unsaturated glucuronyl hydrolase YP_002037007.1 283160 D 512566 CDS YP_002037008.1 194397865 6478884 284361..284852 1 NC_011072.1 identified by match to protein family HMM PF03830; PTS system transporter subunit IIB 284852 6478884 SPG_0293 Streptococcus pneumoniae G54 PTS system transporter subunit IIB YP_002037008.1 284361 D 512566 CDS YP_002037009.1 194397270 6480633 284867..285646 1 NC_011072.1 identified by match to protein family HMM PF03609; PTS system transporter subunit IIC 285646 6480633 SPG_0294 Streptococcus pneumoniae G54 PTS system transporter subunit IIC YP_002037009.1 284867 D 512566 CDS YP_002037010.1 194396674 6479182 285633..286451 1 NC_011072.1 identified by match to protein family HMM PF03613; PTS system transporter subunit IID 286451 6479182 SPG_0295 Streptococcus pneumoniae G54 PTS system transporter subunit IID YP_002037010.1 285633 D 512566 CDS YP_002037011.1 194398560 6479816 286451..286744 1 NC_011072.1 identified by match to protein family HMM PF02699; match to protein family HMM TIGR00739; preprotein translocase subunit 286744 6479816 SPG_0296 Streptococcus pneumoniae G54 preprotein translocase subunit YP_002037011.1 286451 D 512566 CDS YP_002037012.1 194397856 6479089 286766..288667 1 NC_011072.1 identified by match to protein family HMM PF07940; hypothetical protein 288667 6479089 SPG_0297 Streptococcus pneumoniae G54 hypothetical protein YP_002037012.1 286766 D 512566 CDS YP_002037013.1 194397639 6480263 288727..289728 1 NC_011072.1 Chapuy-Regaud,S.; (2003)Inf.& Imm. 71: 2615-2625; identified by match to protein family HMM PF00356; match to protein family HMM PF00532; sugar binding transcriptional regulator RegR 289728 regR 6480263 regR Streptococcus pneumoniae G54 sugar binding transcriptional regulator RegR YP_002037013.1 288727 D 512566 CDS YP_002037014.1 194396928 6478737 complement(289838..290173) 1 NC_011072.1 hypothetical protein 290173 6478737 SPG_0299 Streptococcus pneumoniae G54 hypothetical protein YP_002037014.1 289838 R 512566 CDS YP_002037015.1 194397769 6479780 complement(290184..290426) 1 NC_011072.1 hypothetical protein 290426 6479780 SPG_0300 Streptococcus pneumoniae G54 hypothetical protein YP_002037015.1 290184 R 512566 CDS YP_002037016.1 194398156 6480340 complement(290437..290979) 1 NC_011072.1 identified by glimmer; putative; hypothetical protein 290979 6480340 SPG_0301 Streptococcus pneumoniae G54 hypothetical protein YP_002037016.1 290437 R 512566 CDS YP_002037017.1 194396813 6479648 complement(290995..291189) 1 NC_011072.1 identified by match to protein family HMM PF01381; transcriptional regulator 291189 6479648 SPG_0302 Streptococcus pneumoniae G54 transcriptional regulator YP_002037017.1 290995 R 512566 CDS YP_002037018.1 194398555 6479519 291355..292305 1 NC_011072.1 identified by match to protein family HMM PF01795; match to protein family HMM TIGR00006; S-adenosyl-methyltransferase MraW 292305 mraW 6479519 mraW Streptococcus pneumoniae G54 S-adenosyl-methyltransferase MraW YP_002037018.1 291355 D 512566 CDS YP_002037019.1 194397491 6480088 292317..292634 1 NC_011072.1 identified by match to protein family HMM TIGR02209; cell division protein FtsL 292634 6480088 SPG_0304 Streptococcus pneumoniae G54 cell division protein FtsL YP_002037019.1 292317 D 512566 CDS YP_002037020.1 194397924 6480227 292638..294890 1 NC_011072.1 identified by match to protein family HMM PF00905; match to protein family HMM PF03717; match to protein family HMM PF03793; penicillin-binding protein 2X 294890 pbp2X 6480227 pbp2X Streptococcus pneumoniae G54 penicillin-binding protein 2X YP_002037020.1 292638 D 512566 CDS YP_002037021.1 194398432 6479297 294892..295872 1 NC_011072.1 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; phospho-N-acetylmuramoyl-pentapeptide- transferase 295872 mraY 6479297 mraY Streptococcus pneumoniae G54 phospho-N-acetylmuramoyl-pentapeptide- transferase YP_002037021.1 294892 D 512566 CDS YP_002037022.1 194396752 6480382 296084..296200 1 NC_011072.1 hypothetical protein 296200 6480382 SPG_0307 Streptococcus pneumoniae G54 hypothetical protein YP_002037022.1 296084 D 512566 CDS YP_002037023.1 194397788 6479860 296481..298586 1 NC_011072.1 identified by match to protein family HMM PF00004; match to protein family HMM PF07724; match to protein family HMM PF07728; ATP-dependent Clp protease ATP-binding subunit 298586 6479860 SPG_0308 Streptococcus pneumoniae G54 ATP-dependent Clp protease ATP-binding subunit YP_002037023.1 296481 D 512566 CDS YP_002037024.1 194398223 6480079 complement(298882..299364) 1 NC_011072.1 catalyzes the hydrolysis of S-ribosylhomocysteine to homocysteine and autoinducer-2; S-ribosylhomocysteinase 299364 luxS 6480079 luxS Streptococcus pneumoniae G54 S-ribosylhomocysteinase YP_002037024.1 298882 R 512566 CDS YP_002037025.1 194398668 6479611 complement(299459..300943) 1 NC_011072.1 identified by match to protein family HMM PF08903; hypothetical protein 300943 6479611 SPG_0310 Streptococcus pneumoniae G54 hypothetical protein YP_002037025.1 299459 R 512566 CDS YP_002037026.1 194396992 6479030 301096..302703 1 NC_011072.1 identified by match to protein family HMM PF00128; glucan 1,6-alpha-glucosidase 302703 dexB 6479030 dexB Streptococcus pneumoniae G54 glucan 1,6-alpha-glucosidase YP_002037026.1 301096 D 512566 CDS YP_002037027.1 194398084 6479767 302862..303035 1 NC_011072.1 identified by glimmer; putative; hypothetical protein 303035 6479767 SPG_0312 Streptococcus pneumoniae G54 hypothetical protein YP_002037027.1 302862 D 512566 CDS YP_002037028.1 194398215 6478757 303258..303383 1 NC_011072.1 identified by glimmer; putative; hypothetical protein 303383 6478757 SPG_0313 Streptococcus pneumoniae G54 hypothetical protein YP_002037028.1 303258 D 512566 CDS YP_002037029.1 194398206 6478997 303775..305220 1 NC_011072.1 Bentley, S.D.; 2006 PLOS Genetics 2: 0262-0269 Guidolin,A.; 1994 Inf.Imm. 62:5384-5396; identified by match to protein family HMM PF02916; match to protein family HMM PF03816; match to protein family HMM TIGR00350; integral membrane regulatory protein Wzg 305220 cpsA 6478997 cpsA Streptococcus pneumoniae G54 integral membrane regulatory protein Wzg YP_002037029.1 303775 D 512566 CDS YP_002037030.1 194398654 6479425 305222..305953 1 NC_011072.1 Bentley, S.D.; 2006 PLOS Genetics 2: 0262-0269 Guidolin,A.; 1994 Inf.Imm. 62:5384-5396; identified by match to protein family HMM PF02811; tyrosine-protein phosphatase wzh 305953 cpsB 6479425 cpsB Streptococcus pneumoniae G54 tyrosine-protein phosphatase wzh YP_002037030.1 305222 D 512566 CDS YP_002037031.1 194396683 6478888 305962..306654 1 NC_011072.1 Bentley, S.D.; 2006 PLOS Genetics 2: 0262-0269 Guidolin,A.; 1994 Inf.Imm. 62:5384-5396; identified by match to protein family HMM PF02706; match to protein family HMM TIGR01006; capsular polysaccharide biosynthesis protein Wzh 306654 cpsC 6478888 cpsC Streptococcus pneumoniae G54 capsular polysaccharide biosynthesis protein Wzh YP_002037031.1 305962 D 512566 CDS YP_002037032.1 194397438 6480202 306664..307347 1 NC_011072.1 Bentley, S.D.; 2006 PLOS Genetics 2: 0262-0269 Guidolin,A.; 1994 Inf.Imm. 62:5384-5396; identified by match to protein family HMM TIGR01007; tyrosine-protein kinase wze 307347 cpsD 6480202 cpsD Streptococcus pneumoniae G54 tyrosine-protein kinase wze YP_002037032.1 306664 D 512566 CDS YP_002037033.1 194398447 6480307 307363..308730 1 NC_011072.1 identified by match to protein family HMM PF02397; match to protein family HMM TIGR03025; undecaprenylphosphate glucosephosphotransferase WchA 308730 cpsE 6480307 cpsE Streptococcus pneumoniae G54 undecaprenylphosphate glucosephosphotransferase WchA YP_002037033.1 307363 D 512566 CDS YP_002037034.1 194397568 6479979 308734..309477 1 NC_011072.1 Bentley, S.D.; 2006 PLOS Genetics 2: 0262-0269 Guidolin,A.; 1994 Inf.Imm. 62:5384-5396; identified by match to protein family HMM PF03808; match to protein family HMM TIGR00696; UDP-N-acetyl-D-mannosamine transferase wchO 309477 cpsF 6479979 cpsF Streptococcus pneumoniae G54 UDP-N-acetyl-D-mannosamine transferase wchO YP_002037034.1 308734 D 512566 CDS YP_002037035.1 194398192 6479304 309474..310298 1 NC_011072.1 Bentley, S.D.; 2006 PLOS Genetics 2: 0262-0269 Guidolin,A.; 1994 Inf.Imm. 62:5384-5396; identified by match to protein family HMM PF04991; putative LicD-family phosphotransferase wchP 310298 cpsG 6479304 cpsG Streptococcus pneumoniae G54 putative LicD-family phosphotransferase wchP YP_002037035.1 309474 D 512566 CDS YP_002037036.1 194398669 6480781 310300..311178 1 NC_011072.1 Bentley, S.D.; 2006 PLOS Genetics 2: 0262-0269 Guidolin,A.; 1994 Inf.Imm. 62:5384-5396; identified by match to protein family HMM PF00535; putative rhamnosyl transferase wchQ 311178 cpsH 6480781 cpsH Streptococcus pneumoniae G54 putative rhamnosyl transferase wchQ YP_002037036.1 310300 D 512566 CDS YP_002037037.1 194398659 6479031 311179..312516 1 NC_011072.1 Bentley, S.D.; 2006 PLOS Genetics 2: 0262-0269 Guidolin,A.; 1994 Inf.Imm. 62:5384-5396; oligosaccharide repeat unit polymerase Wzy 312516 cpsI 6479031 cpsI Streptococcus pneumoniae G54 oligosaccharide repeat unit polymerase Wzy YP_002037037.1 311179 D 512566 CDS YP_002037038.1 194398523 6479267 312539..313960 1 NC_011072.1 Bentley, S.D.; 2006 PLOS Genetics 2: 0262-0269 Guidolin,A.; 1994 Inf.Imm. 62:5384-5396; flippase Wzx 313960 cpsJ 6479267 cpsJ Streptococcus pneumoniae G54 flippase Wzx YP_002037038.1 312539 D 512566 CDS YP_002037039.1 194398353 6480146 314024..315112 1 NC_011072.1 Bentley, S.D.; 2006 PLOS Genetics 2: 0262-0269 Guidolin,A.; 1994 Inf.Imm. 62:5384-5396; identified by match to protein family HMM PF02350; match to protein family HMM TIGR00236; UDP-N-acetylglucosamine 2-epimerase mnaA 315112 cpsK 6480146 cpsK Streptococcus pneumoniae G54 UDP-N-acetylglucosamine 2-epimerase mnaA YP_002037039.1 314024 D 512566 CDS YP_002037040.1 194397158 6479905 315151..316020 1 NC_011072.1 Bentley, S.D.; 2006 PLOS Genetics 2: 0262-0269 Guidolin,A.; 1994 Inf.Imm. 62:5384-5396; identified by match to protein family HMM PF00483; match to protein family HMM TIGR01207; glucose-1-phosphate thymidyl transferase rmlA 316020 cpsL 6479905 cpsL Streptococcus pneumoniae G54 glucose-1-phosphate thymidyl transferase rmlA YP_002037040.1 315151 D 512566 CDS YP_002037041.1 194397415 6479199 316021..316617 1 NC_011072.1 Bentley, S.D.; 2006 PLOS Genetics 2: 0262-0269 Guidolin,A.; 1994 Inf.Imm. 62:5384-5396; identified by match to protein family HMM PF00908; dTDP-4-keto-6-deoxyglucose-3,5-epimerase RmlC 316617 cpsM 6479199 cpsM Streptococcus pneumoniae G54 dTDP-4-keto-6-deoxyglucose-3,5-epimerase RmlC YP_002037041.1 316021 D 512566 CDS YP_002037042.1 194397909 6480561 316627..317676 1 NC_011072.1 identified by match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF04321; match to protein family HMM PF07993; match to protein family HMM TIGR01181; dTDP-glucose 4,6-dehydratase RmlB 317676 cpsN 6480561 cpsN Streptococcus pneumoniae G54 dTDP-glucose 4,6-dehydratase RmlB YP_002037042.1 316627 D 512566 CDS YP_002037043.1 194398504 6479051 317742..318593 1 NC_011072.1 Bentley, S.D.; 2006 PLOS Genetics 2: 0262-0269 Guidolin,A.; 1994 Inf.Imm. 62:5384-5396; identified by match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF02719; match to protein family HMM PF04321; match to protein family HMM PF07993; match to protein family HMM TIGR01214; dTDP-4-keto-L-rhamnose reductase RmlD 318593 cpsO 6479051 cpsO Streptococcus pneumoniae G54 dTDP-4-keto-L-rhamnose reductase RmlD YP_002037043.1 317742 D 512566 CDS YP_002037044.1 194397490 6480476 318656..319102 1 NC_011072.1 identified by match to protein family HMM PF03050; IS66-Spn1 transposase 319102 6480476 SPG_0329 Streptococcus pneumoniae G54 IS66-Spn1 transposase YP_002037044.1 318656 D 512566 CDS YP_002037045.1 194398125 6480226 319412..319624 1 NC_011072.1 IS66-Spn1 transposase 319624 6480226 SPG_0330 Streptococcus pneumoniae G54 IS66-Spn1 transposase YP_002037045.1 319412 D 512566 CDS YP_002037046.1 194398722 6480395 319695..319853 1 NC_011072.1 IS66-Spn1 transposase 319853 6480395 SPG_0331 Streptococcus pneumoniae G54 IS66-Spn1 transposase YP_002037046.1 319695 D 512566 CDS YP_002037047.1 194398132 6479093 320052..322034 1 NC_011072.1 identified by match to protein family HMM PF00496; oligopeptide ABC transporter substrate-binding protein 322034 aliA 6479093 aliA Streptococcus pneumoniae G54 oligopeptide ABC transporter substrate-binding protein YP_002037047.1 320052 D 512566 CDS YP_002037048.1 194397693 6480777 322335..327638 1 NC_011072.1 identified by match to protein family HMM PF00754; match to protein family HMM PF04650; match to protein family HMM TIGR01167; match to protein family HMM TIGR01168; cell wall surface anchor family protein 327638 6480777 SPG_0333 Streptococcus pneumoniae G54 cell wall surface anchor family protein YP_002037048.1 322335 D 512566 CDS YP_002037049.1 194397476 6479083 complement(327805..329964) 1 NC_011072.1 identified by match to protein family HMM PF00905; match to protein family HMM PF00912; match to protein family HMM TIGR02074; penicillin-binding protein 1A 329964 6479083 SPG_0334 Streptococcus pneumoniae G54 penicillin-binding protein 1A YP_002037049.1 327805 R 512566 CDS YP_002037050.1 194398051 6479961 complement(329961..330557) 1 NC_011072.1 functions in homologous recombination, DNA repair, and chromosome segregation; binds preferentially to three- and four-stranded DNA intermediates; introduces specific nick sites in four-stranded DNA substrates; functions similarly to Escherichia coli RuvC; Holliday junction-specific endonuclease 330557 recU 6479961 recU Streptococcus pneumoniae G54 Holliday junction-specific endonuclease YP_002037050.1 329961 R 512566 CDS YP_002037051.1 194398558 6478688 330623..331150 1 NC_011072.1 identified by match to protein family HMM PF06908; hypothetical protein 331150 6478688 SPG_0336 Streptococcus pneumoniae G54 hypothetical protein YP_002037051.1 330623 D 512566 CDS YP_002037052.1 194396893 6479542 331220..331549 1 NC_011072.1 identified by match to protein family HMM PF05103; hypothetical protein 331549 6479542 SPG_0337 Streptococcus pneumoniae G54 hypothetical protein YP_002037052.1 331220 D 512566 CDS YP_002037053.1 194397622 6479486 complement(331554..331667) 1 NC_011072.1 identified by glimmer; putative; hypothetical protein 331667 6479486 SPG_0338 Streptococcus pneumoniae G54 hypothetical protein YP_002037053.1 331554 R 512566 CDS YP_002037054.1 194398094 6478853 332035..333192 1 NC_011072.1 identified by match to protein family HMM PF01170; hypothetical protein 333192 6478853 SPG_0339 Streptococcus pneumoniae G54 hypothetical protein YP_002037054.1 332035 D 512566 CDS YP_002037055.1 194396726 6480478 333205..334599 1 NC_011072.1 hypothetical protein 334599 6480478 SPG_0340 Streptococcus pneumoniae G54 hypothetical protein YP_002037055.1 333205 D 512566 CDS YP_002037056.1 194397196 6479673 334675..336099 1 NC_011072.1 catalyzes the formation of D-ribulose 5-phosphate from 6-phospho-D-gluconate; 6-phosphogluconate dehydrogenase 336099 gnd 6479673 gnd Streptococcus pneumoniae G54 6-phosphogluconate dehydrogenase YP_002037056.1 334675 D 512566 CDS YP_002037057.1 194396773 6479772 336111..336800 1 NC_011072.1 Ulijasz et al., J Bacteriol. 2004 186(23):8123-36.; identified by match to protein family HMM PF00072; match to protein family HMM PF00486; RitR response regulator 336800 ritR 6479772 ritR Streptococcus pneumoniae G54 RitR response regulator YP_002037057.1 336111 D 512566 CDS YP_002037058.1 194397519 6479692 336898..337917 1 NC_011072.1 identified by match to protein family HMM PF01473; choline-binding protein C 337917 cbpC 6479692 cbpC Streptococcus pneumoniae G54 choline-binding protein C YP_002037058.1 336898 D 512566 CDS YP_002037059.1 194396915 6478894 complement(338035..339267) 1 NC_011072.1 hypothetical protein 339267 6478894 SPG_0344 Streptococcus pneumoniae G54 hypothetical protein YP_002037059.1 338035 R 512566 CDS YP_002037060.1 194398757 6480640 340966..341145 1 NC_011072.1 identified by match to protein family HMM PF01473; hypothetical protein 341145 6480640 SPG_0345 Streptococcus pneumoniae G54 hypothetical protein YP_002037060.1 340966 D 512566 CDS YP_002037061.1 194398279 6480697 341267..342145 1 NC_011072.1 identified by match to protein family HMM PF00288; match to protein family HMM PF08544; match to protein family HMM TIGR00549; mevalonate kinase 342145 mvaK1 6480697 mvaK1 Streptococcus pneumoniae G54 mevalonate kinase YP_002037061.1 341267 D 512566 CDS YP_002037062.1 194397794 6478709 342127..343080 1 NC_011072.1 identified by match to protein family HMM PF00288; match to protein family HMM PF08544; match to protein family HMM TIGR01240; mevalonate diphosphate decarboxylase 343080 mvaD 6478709 mvaD Streptococcus pneumoniae G54 mevalonate diphosphate decarboxylase YP_002037062.1 342127 D 512566 CDS YP_002037063.1 194398461 6479747 343067..344074 1 NC_011072.1 identified by match to protein family HMM PF00288; match to protein family HMM PF08544; match to protein family HMM TIGR01220; phosphomevalonate kinase 344074 mvaK2 6479747 mvaK2 Streptococcus pneumoniae G54 phosphomevalonate kinase YP_002037063.1 343067 D 512566 CDS YP_002037064.1 194397821 6480774 344058..345068 1 NC_011072.1 catalyzes the isomerization of isopentenyl pyrophosphate to dimethylallyl diphosphate; isopentenyl pyrophosphate isomerase 345068 6480774 SPG_0349 Streptococcus pneumoniae G54 isopentenyl pyrophosphate isomerase YP_002037064.1 344058 D 512566 CDS YP_002037065.1 194397521 6480820 345146..345844 1 NC_011072.1 hypothetical protein 345844 6480820 SPG_0350 Streptococcus pneumoniae G54 hypothetical protein YP_002037065.1 345146 D 512566 CDS YP_002037066.1 194396904 6478990 345841..346836 1 NC_011072.1 identified by match to protein family HMM PF02518; match to protein family HMM PF07730; histidine kinase 346836 6478990 SPG_0351 Streptococcus pneumoniae G54 histidine kinase YP_002037066.1 345841 D 512566 CDS YP_002037067.1 194398711 6480209 346850..347482 1 NC_011072.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00196; match to protein family HMM PF08281; response regulator 347482 6480209 SPG_0352 Streptococcus pneumoniae G54 response regulator YP_002037067.1 346850 D 512566 CDS YP_002037068.1 194397967 6479484 347696..347914 1 NC_011072.1 hypothetical protein 347914 6479484 SPG_0353 Streptococcus pneumoniae G54 hypothetical protein YP_002037068.1 347696 D 512566 CDS YP_002037069.1 194398638 6479588 347969..348241 1 NC_011072.1 DNA alkylation repair enzyme 348241 6479588 SPG_0354 Streptococcus pneumoniae G54 DNA alkylation repair enzyme YP_002037069.1 347969 D 512566 CDS YP_002037070.1 194398002 6478958 348391..348630 1 NC_011072.1 hypothetical protein 348630 6478958 SPG_0355 Streptococcus pneumoniae G54 hypothetical protein YP_002037070.1 348391 D 512566 CDS YP_002037071.1 194397667 6479228 348711..349532 1 NC_011072.1 identified by match to protein family HMM PF00089; match to protein family HMM PF01473; choline binding protein G 349532 cbpG 6479228 cbpG Streptococcus pneumoniae G54 choline binding protein G YP_002037071.1 348711 D 512566 CDS YP_002037072.1 194397062 6479375 349551..349976 1 NC_011072.1 choline-binding protein F, point mutation 349976 6479375 SPG_0357 Streptococcus pneumoniae G54 choline-binding protein F, point mutation YP_002037072.1 349551 D 512566 CDS YP_002037073.1 194397696 6479728 350094..350573 1 NC_011072.1 identified by match to protein family HMM PF01473; choline-binding protein F, point mutation 350573 6479728 SPG_0358 Streptococcus pneumoniae G54 choline-binding protein F, point mutation YP_002037073.1 350094 D 512566 CDS YP_002037074.1 194397092 6479528 complement(350701..350850) 1 NC_011072.1 IS3-Spn1 transposase 350850 6479528 SPG_0359 Streptococcus pneumoniae G54 IS3-Spn1 transposase YP_002037074.1 350701 R 512566 CDS YP_002037075.1 194398378 6480672 complement(350834..351187) 1 NC_011072.1 IS3-Spn1 transposase 351187 6480672 SPG_0360 Streptococcus pneumoniae G54 IS3-Spn1 transposase YP_002037075.1 350834 R 512566 CDS YP_002037076.1 194397927 6478676 complement(351409..351924) 1 NC_011072.1 identified by match to protein family HMM PF01527; IS3-Spn1 transposase 351924 6478676 SPG_0361 Streptococcus pneumoniae G54 IS3-Spn1 transposase YP_002037076.1 351409 R 512566 CDS YP_002037077.1 194397429 6478783 352133..353890 1 NC_011072.1 identified by match to protein family HMM PF02302; match to protein family HMM PF02378; match to protein family HMM TIGR00851; PTS system transporter subunit IIBC 353890 6478783 SPG_0362 Streptococcus pneumoniae G54 PTS system transporter subunit IIBC YP_002037077.1 352133 D 512566 CDS YP_002037078.1 194396953 6480162 353914..355869 1 NC_011072.1 identified by match to protein family HMM PF08279; putative transcriptional regulator MtlR 355869 6480162 SPG_0363 Streptococcus pneumoniae G54 putative transcriptional regulator MtlR YP_002037078.1 353914 D 512566 CDS YP_002037079.1 194398739 6479903 355871..356308 1 NC_011072.1 identified by match to protein family HMM PF00359; PTS system transporter subunit IIA 356308 6479903 SPG_0364 Streptococcus pneumoniae G54 PTS system transporter subunit IIA YP_002037079.1 355871 D 512566 CDS YP_002037080.1 194397233 6478924 356370..357506 1 NC_011072.1 identified by match to protein family HMM PF01232; match to protein family HMM PF08125; mannitol-1-phosphate 5-dehydrogenase 357506 6478924 SPG_0365 Streptococcus pneumoniae G54 mannitol-1-phosphate 5-dehydrogenase YP_002037080.1 356370 D 512566 CDS YP_002037081.1 194397549 6480277 357875..357988 1 NC_011072.1 hypothetical protein 357988 6480277 SPG_0366 Streptococcus pneumoniae G54 hypothetical protein YP_002037081.1 357875 D 512566 CDS YP_002037082.1 194398157 6479243 358292..359575 1 NC_011072.1 Tig; RopA; peptidyl-prolyl cis/trans isomerase; promotes folding of newly synthesized proteins; binds ribosomal 50S subunit; forms a homodimer; trigger factor 359575 tig 6479243 tig Streptococcus pneumoniae G54 trigger factor YP_002037082.1 358292 D 512566 CDS YP_002037083.1 194396884 6480593 complement(359623..361989) 1 NC_011072.1 identified by match to protein family HMM TIGR01448; helicase, RecD/TraA family 361989 6480593 SPG_0368 Streptococcus pneumoniae G54 helicase, RecD/TraA family YP_002037083.1 359623 R 512566 CDS YP_002037084.1 194397839 6479485 complement(362268..362882) 1 NC_011072.1 identified by match to protein family HMM PF00717; match to protein family HMM TIGR02227; signal peptidase I 362882 6479485 SPG_0369 Streptococcus pneumoniae G54 signal peptidase I YP_002037084.1 362268 R 512566 CDS YP_002037085.1 194398393 6480457 complement(362886..363767) 1 NC_011072.1 An endonuclease that specifically degrades the RNA strand of RNA-DNA hybrids; ribonuclease HIII 363767 rnhC 6480457 rnhC Streptococcus pneumoniae G54 ribonuclease HIII YP_002037085.1 362886 R 512566 CDS YP_002037086.1 194397148 6478804 363854..364156 1 NC_011072.1 hypothetical protein 364156 6478804 SPG_0371 Streptococcus pneumoniae G54 hypothetical protein YP_002037086.1 363854 D 512566 CDS YP_002037087.1 194397449 6480502 364153..364701 1 NC_011072.1 identified by match to protein family HMM PF02674; CvpA family protein 364701 cvpA 6480502 cvpA Streptococcus pneumoniae G54 CvpA family protein YP_002037087.1 364153 D 512566 CDS YP_002037088.1 194397995 6480503 364805..367141 1 NC_011072.1 function of MutS2 is unknown. It should not be considered a DNA mismactch repair. MutS2 lineage is currently functionally uncharacterized.; identified by match to protein family HMM PF00488; match to protein family HMM PF01713; match to protein family HMM TIGR01069; MutS2 family protein 367141 6480503 SPG_0373 Streptococcus pneumoniae G54 MutS2 family protein YP_002037088.1 364805 D 512566 CDS YP_002037089.1 194397921 6479197 367483..368805 1 NC_011072.1 identified by match to protein family HMM PF01235; match to protein family HMM TIGR00835; sodium:alanine symporter family 368805 6479197 SPG_0374 Streptococcus pneumoniae G54 sodium:alanine symporter family YP_002037089.1 367483 D 512566 CDS YP_002037090.1 194397084 6479027 369023..369571 1 NC_011072.1 identified by glimmer; putative; hypothetical protein 369571 6479027 SPG_0375 Streptococcus pneumoniae G54 hypothetical protein YP_002037090.1 369023 D 512566 CDS YP_002037091.1 194397536 6479732 369681..370580 1 NC_011072.1 identified by match to protein family HMM PF03595; exfoliative toxin A 370580 6479732 SPG_0376 Streptococcus pneumoniae G54 exfoliative toxin A YP_002037091.1 369681 D 512566 CDS YP_002037092.1 194397764 6478792 complement(370605..371879) 1 NC_011072.1 catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; seryl-tRNA synthetase 371879 serS 6478792 serS Streptococcus pneumoniae G54 seryl-tRNA synthetase YP_002037092.1 370605 R 512566 CDS YP_002037093.1 194398759 6479716 complement(372093..372464) 1 NC_011072.1 identified by match to protein family HMM PF06115; hypothetical protein 372464 6479716 SPG_0378 Streptococcus pneumoniae G54 hypothetical protein YP_002037093.1 372093 R 512566 CDS YP_002037094.1 194396653 6480699 complement(372467..373831) 1 NC_011072.1 catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP; lysine and threonine sensitive; aspartate kinase 373831 6480699 SPG_0379 Streptococcus pneumoniae G54 aspartate kinase YP_002037094.1 372467 R 512566 CDS YP_002037095.1 194397302 6480143 complement(373915..374208) 1 NC_011072.1 hypothetical protein 374208 6480143 SPG_0380 Streptococcus pneumoniae G54 hypothetical protein YP_002037095.1 373915 R 512566 CDS YP_002037096.1 194397371 6479178 374200..375009 1 NC_011072.1 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; enoyl-CoA hydratase 375009 fabM 6479178 fabM Streptococcus pneumoniae G54 enoyl-CoA hydratase YP_002037096.1 374200 D 512566 CDS YP_002037097.1 194398281 6480534 375080..375514 1 NC_011072.1 Sullavik, M.C. 1995 Mol.Med.1:436-446; identified by match to protein family HMM PF01047; match to protein family HMM PF03965; fatty acid biosynthesis transcriptional regulator 375514 fabT 6480534 fabT Streptococcus pneumoniae G54 fatty acid biosynthesis transcriptional regulator YP_002037097.1 375080 D 512566 CDS YP_002037098.1 194398322 6479318 375514..376488 1 NC_011072.1 FabH; beta-ketoacyl-acyl carrier protein synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs; 3-oxoacyl-(acyl carrier protein) synthase III 376488 fabH 6479318 fabH Streptococcus pneumoniae G54 3-oxoacyl-(acyl carrier protein) synthase III YP_002037098.1 375514 D 512566 CDS YP_002037099.1 194396912 6478650 376548..376772 1 NC_011072.1 carries the fatty acid chain in fatty acid biosynthesis; acyl carrier protein 376772 acpP 6478650 acpP Streptococcus pneumoniae G54 acyl carrier protein YP_002037099.1 376548 D 512566 CDS YP_002037100.1 194397374 6479959 376891..377865 1 NC_011072.1 identified by match to protein family HMM PF03060; match to protein family HMM TIGR03151; enoyl-acyl carrier protein (ACP) reductase II 377865 fabK 6479959 fabK Streptococcus pneumoniae G54 enoyl-acyl carrier protein (ACP) reductase II YP_002037100.1 376891 D 512566 CDS YP_002037101.1 194398122 6480245 377858..378778 1 NC_011072.1 identified by match to protein family HMM PF00698; match to protein family HMM TIGR00128; malonyl CoA-acyl carrier protein transacylase 378778 fabD 6480245 fabD Streptococcus pneumoniae G54 malonyl CoA-acyl carrier protein transacylase YP_002037101.1 377858 D 512566 CDS YP_002037102.1 194398106 6479712 378812..379543 1 NC_011072.1 catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis; 3-ketoacyl-(acyl-carrier-protein) reductase 379543 fabG 6479712 fabG Streptococcus pneumoniae G54 3-ketoacyl-(acyl-carrier-protein) reductase YP_002037102.1 378812 D 512566 CDS YP_002037103.1 194398564 6480617 379565..380800 1 NC_011072.1 FabF; beta-ketoacyl-ACP synthase II, KASII; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP; 3-oxoacyl-(acyl carrier protein) synthase II 380800 fabF 6480617 fabF Streptococcus pneumoniae G54 3-oxoacyl-(acyl carrier protein) synthase II YP_002037103.1 379565 D 512566 CDS YP_002037104.1 194397305 6479122 380803..381288 1 NC_011072.1 composes the biotin carboxyl carrier protein subunit of the acetyl-CoA carboxylase complex, the enzyme that catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, which in turn controls the rate of fatty acid metabolism; acetyl-CoA carboxylase biotin carboxyl carrier protein subunit 381288 accB 6479122 accB Streptococcus pneumoniae G54 acetyl-CoA carboxylase biotin carboxyl carrier protein subunit YP_002037104.1 380803 D 512566 CDS YP_002037105.1 194397619 6478702 381285..381707 1 NC_011072.1 in Pseudomonas aeruginosa this enzyme is a trimer of dimers; essential for membrane formation; performs third step of type II fatty acid biosynthesis; catalyzes dehydration of (3R)-hydroxyacyl-ACP to trans-2-acyl-ACP; (3R)-hydroxymyristoyl-ACP dehydratase 381707 fabZ 6478702 fabZ Streptococcus pneumoniae G54 (3R)-hydroxymyristoyl-ACP dehydratase YP_002037105.1 381285 D 512566 CDS YP_002037106.1 194397759 6479414 381719..383086 1 NC_011072.1 an AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism; acetyl-CoA carboxylase biotin carboxylase subunit 383086 accC 6479414 accC Streptococcus pneumoniae G54 acetyl-CoA carboxylase biotin carboxylase subunit YP_002037106.1 381719 D 512566 CDS YP_002037107.1 194397049 6480447 383123..383989 1 NC_011072.1 catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer of AccA2D2 subunits; acetyl-CoA carboxylase subunit beta 383989 accD 6480447 accD Streptococcus pneumoniae G54 acetyl-CoA carboxylase subunit beta YP_002037107.1 383123 D 512566 CDS YP_002037108.1 194398167 6479706 383986..384753 1 NC_011072.1 catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer composed of two alpha (AccA) and two beta (AccD) subunits; one of the two catalytic subunits that can form the acetyl CoA carboxylase enzyme together with a carrier protein; these proteins present a shorter N-terminus; acetyl-CoA carboxylase subunit alpha 384753 accA 6479706 accA Streptococcus pneumoniae G54 acetyl-CoA carboxylase subunit alpha YP_002037108.1 383986 D 512566 CDS YP_002037109.1 194398539 6480375 384912..385097 1 NC_011072.1 hypothetical protein 385097 6480375 SPG_0394 Streptococcus pneumoniae G54 hypothetical protein YP_002037109.1 384912 D 512566 CDS YP_002037110.1 194396982 6480538 385154..385588 1 NC_011072.1 hypothetical protein 385588 6480538 SPG_0395 Streptococcus pneumoniae G54 hypothetical protein YP_002037110.1 385154 D 512566 CDS YP_002037111.1 194396779 6479729 complement(385887..386309) 1 NC_011072.1 Regulates rRNA biosynthesis by transcriptional antitermination; transcription antitermination protein NusB 386309 nusB 6479729 nusB Streptococcus pneumoniae G54 transcription antitermination protein NusB YP_002037111.1 385887 R 512566 CDS YP_002037112.1 194396821 6480016 complement(386302..386691) 1 NC_011072.1 identified by match to protein family HMM PF03780; hypothetical protein 386691 6480016 SPG_0397 Streptococcus pneumoniae G54 hypothetical protein YP_002037112.1 386302 R 512566 CDS YP_002037113.1 194398099 6479080 complement(386713..387273) 1 NC_011072.1 Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA; elongation factor P 387273 6479080 SPG_0398 Streptococcus pneumoniae G54 elongation factor P YP_002037113.1 386713 R 512566 CDS YP_002037114.1 194398551 6480643 complement(387402..388844) 1 NC_011072.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; aspartyl/glutamyl-tRNA amidotransferase subunit B 388844 gatB 6480643 gatB Streptococcus pneumoniae G54 aspartyl/glutamyl-tRNA amidotransferase subunit B YP_002037114.1 387402 R 512566 CDS YP_002037115.1 194397146 6479893 complement(388844..390310) 1 NC_011072.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; aspartyl/glutamyl-tRNA amidotransferase subunit A 390310 gatA 6479893 gatA Streptococcus pneumoniae G54 aspartyl/glutamyl-tRNA amidotransferase subunit A YP_002037115.1 388844 R 512566 CDS YP_002037116.1 194397149 6480091 complement(390310..390612) 1 NC_011072.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; some Mycoplasma proteins contain an N-terminal fusion to an unknown domain; aspartyl/glutamyl-tRNA amidotransferase subunit C 390612 gatC 6480091 gatC Streptococcus pneumoniae G54 aspartyl/glutamyl-tRNA amidotransferase subunit C YP_002037116.1 390310 R 512566 CDS YP_002037117.1 194398202 6480235 390825..392369 1 NC_011072.1 stimulates the release of release factors 1 and 2 from the ribosome after hydrolysis of the ester bond in peptidyl-tRNA has occurred; GDP/GTP-binding protein; peptide chain release factor 3 392369 prfC 6480235 prfC Streptococcus pneumoniae G54 peptide chain release factor 3 YP_002037117.1 390825 D 512566 CDS YP_002037118.1 194396811 6478832 393085..393273 1 NC_011072.1 required for 70S ribosome assembly; 50S ribosomal protein L28 393273 rpmB 6478832 rpmB Streptococcus pneumoniae G54 50S ribosomal protein L28 YP_002037118.1 393085 D 512566 CDS YP_002037119.1 194398351 6479286 393430..393795 1 NC_011072.1 identified by match to protein family HMM PF03780; hypothetical protein 393795 6479286 SPG_0404 Streptococcus pneumoniae G54 hypothetical protein YP_002037119.1 393430 D 512566 CDS YP_002037120.1 194398012 6480406 393798..395465 1 NC_011072.1 identified by match to protein family HMM PF02734; match to protein family HMM TIGR03599; hypothetical protein 395465 6480406 SPG_0405 Streptococcus pneumoniae G54 hypothetical protein YP_002037120.1 393798 D 512566 CDS YP_002037121.1 194398621 6479440 complement(395509..396765) 1 NC_011072.1 identified by match to protein family HMM PF01610; IS1167 transposase 396765 6479440 SPG_0406 Streptococcus pneumoniae G54 IS1167 transposase YP_002037121.1 395509 R 512566 CDS YP_002037122.1 194396792 6479465 397089..398789 1 NC_011072.1 catalyzes the formation of 2-acetolactate from pyruvate; also known as acetolactate synthase large subunit; acetolactate synthase catalytic subunit 398789 6479465 SPG_0407 Streptococcus pneumoniae G54 acetolactate synthase catalytic subunit YP_002037122.1 397089 D 512566 CDS YP_002037123.1 194396942 6479824 398782..399258 1 NC_011072.1 with IlvI catalyzes the formation of 2-acetolactate from pyruvate, the small subunit is required for full activity and valine sensitivity; E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates, valine sensitivity and affinity for cofactors; also known as acetolactate synthase 3 small subunit; acetolactate synthase 3 regulatory subunit 399258 ilvH 6479824 ilvH Streptococcus pneumoniae G54 acetolactate synthase 3 regulatory subunit YP_002037123.1 398782 D 512566 CDS YP_002037124.1 194397070 6480153 399324..400346 1 NC_011072.1 catalyzes the formation of (R)-2,3-dihydroxy-3-methylbutanoate from (S)-2-hydroxy-2-methyl-3-oxobutanoate in valine and isoleucine biosynthesis; ketol-acid reductoisomerase 400346 6480153 SPG_0409 Streptococcus pneumoniae G54 ketol-acid reductoisomerase YP_002037124.1 399324 D 512566 CDS YP_002037125.1 194398643 6479789 400453..400689 1 NC_011072.1 hypothetical protein 400689 6479789 SPG_0410 Streptococcus pneumoniae G54 hypothetical protein YP_002037125.1 400453 D 512566 CDS YP_002037126.1 194397212 6479429 400927..401283 1 NC_011072.1 hypothetical protein 401283 6479429 SPG_0411 Streptococcus pneumoniae G54 hypothetical protein YP_002037126.1 400927 D 512566 CDS YP_002037127.1 194397917 6480671 401333..402583 1 NC_011072.1 catalyzes the formation of 2-oxobutanoate from L-threonine; biosynthetic; threonine dehydratase 402583 6480671 SPG_0412 Streptococcus pneumoniae G54 threonine dehydratase YP_002037127.1 401333 D 512566 CDS YP_002037128.1 194398727 6479174 402725..402913 1 NC_011072.1 hypothetical protein 402913 6479174 SPG_0413 Streptococcus pneumoniae G54 hypothetical protein YP_002037128.1 402725 D 512566 CDS YP_002037129.1 194396927 6479580 403454..403669 1 NC_011072.1 hypothetical protein 403669 6479580 SPG_0414 Streptococcus pneumoniae G54 hypothetical protein YP_002037129.1 403454 D 512566 CDS YP_002037130.1 194396698 6480152 complement(403868..404632) 1 NC_011072.1 identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 404632 6480152 SPG_0415 Streptococcus pneumoniae G54 ABC transporter ATP-binding protein YP_002037130.1 403868 R 512566 CDS YP_002037131.1 194397297 6479696 complement(404632..406197) 1 NC_011072.1 identified by match to protein family HMM PF00497; match to protein family HMM PF00528; match to protein family HMM TIGR01726; amino acid ABC transporter amino acid-binding protein/permease 406197 6479696 SPG_0416 Streptococcus pneumoniae G54 amino acid ABC transporter amino acid-binding protein/permease YP_002037131.1 404632 R 512566 CDS YP_002037132.1 194398470 6478711 406335..408224 1 NC_011072.1 hypothetical protein 408224 6478711 SPG_0418 Streptococcus pneumoniae G54 hypothetical protein YP_002037132.1 406335 D 512566 CDS YP_002037133.1 194397880 6480677 complement(408221..408391) 1 NC_011072.1 hypothetical protein 408391 6480677 SPG_0417 Streptococcus pneumoniae G54 hypothetical protein YP_002037133.1 408221 R 512566 CDS YP_002037134.1 194397136 6480361 complement(408423..409553) 1 NC_011072.1 identified by match to protein family HMM PF02371; transposase 409553 6480361 SPG_0419 Streptococcus pneumoniae G54 transposase YP_002037134.1 408423 R 512566 CDS YP_002037135.1 194397623 6479733 409640..409777 1 NC_011072.1 identified by glimmer; putative; hypothetical protein 409777 6479733 SPG_0420 Streptococcus pneumoniae G54 hypothetical protein YP_002037135.1 409640 D 512566 CDS YP_002037136.1 194397317 6478854 409808..410653 1 NC_011072.1 BacA; phosphatase activity in Escherichia coli not kinase; involved in bacitracin resistance as bacitracin supposedly sequesters undecaprenyl disphosphate which reduces the pool of lipid carrier available to the cell; undecaprenyl pyrophosphate phosphatase 410653 bacA 6478854 bacA Streptococcus pneumoniae G54 undecaprenyl pyrophosphate phosphatase YP_002037136.1 409808 D 512566 CDS YP_002037137.1 194398025 6480423 410646..410774 1 NC_011072.1 hypothetical protein 410774 6480423 SPG_0422 Streptococcus pneumoniae G54 hypothetical protein YP_002037137.1 410646 D 512566 CDS YP_002037138.1 194397431 6478655 complement(410800..411861) 1 NC_011072.1 involved in translesion DNA polymerization with beta clamp of polymerase III; belongs to Y family of polymerases; does not contain proofreading function; DNA polymerase IV 411861 dinB 6478655 dinB Streptococcus pneumoniae G54 DNA polymerase IV YP_002037138.1 410800 R 512566 CDS YP_002037139.1 194396817 6480045 412209..414533 1 NC_011072.1 identified by match to protein family HMM PF01228; match to protein family HMM PF02901; match to protein family HMM TIGR01255; formate acetyltransferase 414533 6480045 SPG_0424 Streptococcus pneumoniae G54 formate acetyltransferase YP_002037139.1 412209 D 512566 CDS YP_002037140.1 194398358 6479095 complement(414900..415118) 1 NC_011072.1 hypothetical protein 415118 6479095 SPG_0425 Streptococcus pneumoniae G54 hypothetical protein YP_002037140.1 414900 R 512566 CDS YP_002037141.1 194397066 6480755 complement(415445..415729) 1 NC_011072.1 hypothetical protein 415729 6480755 SPG_0426 Streptococcus pneumoniae G54 hypothetical protein YP_002037141.1 415445 R 512566 CDS YP_002037142.1 194397694 6479720 416949..417086 1 NC_011072.1 hypothetical protein 417086 6479720 SPG_0427 Streptococcus pneumoniae G54 hypothetical protein YP_002037142.1 416949 D 512566 CDS YP_002037143.1 194397128 6479448 complement(417326..418549) 1 NC_011072.1 identified by match to protein family HMM PF00480; ROK family protein 418549 6479448 SPG_0428 Streptococcus pneumoniae G54 ROK family protein YP_002037143.1 417326 R 512566 CDS YP_002037144.1 194396747 6480004 418717..420039 1 NC_011072.1 identified by match to protein family HMM PF02378; match to protein family HMM TIGR00410; PTS system transporter subunit IIC 420039 6480004 SPG_0429 Streptococcus pneumoniae G54 PTS system transporter subunit IIC YP_002037144.1 418717 D 512566 CDS YP_002037145.1 194398649 6479735 420041..420235 1 NC_011072.1 contains potential frameshift; hypothetical protein 420235 6479735 SPG_0430 Streptococcus pneumoniae G54 hypothetical protein YP_002037145.1 420041 D 512566 CDS YP_002037146.1 194398079 6479356 420288..421928 1 NC_011072.1 contains potential frameshift; hypothetical protein 421928 6479356 SPG_0431 Streptococcus pneumoniae G54 hypothetical protein YP_002037146.1 420288 D 512566 CDS YP_002037147.1 194396923 6479007 422096..422440 1 NC_011072.1 identified by match to protein family HMM PF02255; PTS system transporter subunit IIA 422440 6479007 SPG_0432 Streptococcus pneumoniae G54 PTS system transporter subunit IIA YP_002037147.1 422096 D 512566 CDS YP_002037148.1 194397523 6479803 422450..423862 1 NC_011072.1 catalyzes the formation of 6-phospho-galactose from a 6-phospho-beta-galactoside; 6-phospho-beta-galactosidase 423862 6479803 SPG_0433 Streptococcus pneumoniae G54 6-phospho-beta-galactosidase YP_002037148.1 422450 D 512566 CDS YP_002037149.1 194397288 6479535 423931..425610 1 NC_011072.1 identified by match to protein family HMM PF02302; match to protein family HMM PF02378; match to protein family HMM TIGR00410; PTS system transporter subunit IIBC 425610 6479535 SPG_0434 Streptococcus pneumoniae G54 PTS system transporter subunit IIBC YP_002037149.1 423931 D 512566 CDS YP_002037150.1 194397895 6478965 complement(425735..427174) 1 NC_011072.1 identified by match to protein family HMM PF02386; Trk transporter membrane-spanning protein 427174 6478965 SPG_0435 Streptococcus pneumoniae G54 Trk transporter membrane-spanning protein YP_002037150.1 425735 R 512566 CDS YP_002037151.1 194398712 6479509 complement(427178..428527) 1 NC_011072.1 involved in potassium uptake; found to be peripherally associated with the inner membrane in Escherichia coli; contains an NAD-binding domain; potassium transporter peripheral membrane component 428527 trkA 6479509 trkA Streptococcus pneumoniae G54 potassium transporter peripheral membrane component YP_002037151.1 427178 R 512566 CDS YP_002037152.1 194396648 6479551 428716..429564 1 NC_011072.1 identified by match to protein family HMM PF01887; hypothetical protein 429564 6479551 SPG_0437 Streptococcus pneumoniae G54 hypothetical protein YP_002037152.1 428716 D 512566 CDS YP_002037153.1 194397661 6480389 429579..430127 1 NC_011072.1 identified by match to protein family HMM PF07155; hypothetical protein 430127 6480389 SPG_0438 Streptococcus pneumoniae G54 hypothetical protein YP_002037153.1 429579 D 512566 CDS YP_002037154.1 194398475 6479566 430448..432130 1 NC_011072.1 identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 432130 6479566 SPG_0439 Streptococcus pneumoniae G54 ABC transporter ATP-binding protein YP_002037154.1 430448 D 512566 CDS YP_002037155.1 194398545 6480304 432115..432945 1 NC_011072.1 identified by match to protein family HMM PF02361; cobalt transport protein 432945 6480304 SPG_0440 Streptococcus pneumoniae G54 cobalt transport protein YP_002037155.1 432115 D 512566 CDS YP_002037156.1 194398514 6480105 433138..433641 1 NC_011072.1 identified by match to protein family HMM PF00588; TrmH family RNA methyltransferase 433641 6480105 SPG_0441 Streptococcus pneumoniae G54 TrmH family RNA methyltransferase YP_002037156.1 433138 D 512566 CDS YP_002037157.1 194397763 6480386 434094..434657 1 NC_011072.1 hypothetical protein 434657 6480386 SPG_0442 Streptococcus pneumoniae G54 hypothetical protein YP_002037157.1 434094 D 512566 CDS YP_002037158.1 194397240 6479715 434647..435297 1 NC_011072.1 identified by match to protein family HMM PF01569; hypothetical protein 435297 6479715 SPG_0443 Streptococcus pneumoniae G54 hypothetical protein YP_002037158.1 434647 D 512566 CDS YP_002037159.1 194397618 6480336 435325..435714 1 NC_011072.1 hypothetical protein 435714 6480336 SPG_0444 Streptococcus pneumoniae G54 hypothetical protein YP_002037159.1 435325 D 512566 CDS YP_002037160.1 194398745 6478729 435719..436168 1 NC_011072.1 hypothetical protein 436168 6478729 SPG_0445 Streptococcus pneumoniae G54 hypothetical protein YP_002037160.1 435719 D 512566 CDS YP_002037161.1 194398024 6478647 436296..436883 1 NC_011072.1 participates in both the initiation and recycling phases of transcription; in the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling; DNA-directed RNA polymerase subunit delta 436883 rpoE 6478647 rpoE Streptococcus pneumoniae G54 DNA-directed RNA polymerase subunit delta YP_002037161.1 436296 D 512566 CDS YP_002037162.1 194397397 6478654 complement(436973..437098) 1 NC_011072.1 hypothetical protein 437098 6478654 SPG_0447 Streptococcus pneumoniae G54 hypothetical protein YP_002037162.1 436973 R 512566 CDS YP_002037163.1 194396787 6480533 437273..438880 1 NC_011072.1 CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer; CTP synthetase 438880 pyrG 6480533 pyrG Streptococcus pneumoniae G54 CTP synthetase YP_002037163.1 437273 D 512566 CDS YP_002037164.1 194396795 6480083 complement(439439..441070) 1 NC_011072.1 identified by match to protein family HMM PF02690; match to protein family HMM TIGR00704; Na/Pi-cotransporter II-related protein 441070 6480083 SPG_0449 Streptococcus pneumoniae G54 Na/Pi-cotransporter II-related protein YP_002037164.1 439439 R 512566 CDS YP_002037165.1 194398611 6479783 441435..444923 1 NC_011072.1 identified by match to protein family HMM PF00754; match to protein family HMM PF03644; match to protein family HMM PF07523; endo-beta-N-acetylglucosaminidase 444923 6479783 SPG_0450 Streptococcus pneumoniae G54 endo-beta-N-acetylglucosaminidase YP_002037165.1 441435 D 512566 CDS YP_002037166.1 194398422 6478911 444990..446342 1 NC_011072.1 identified by match to protein family HMM PF00746; match to protein family HMM PF07501; match to protein family HMM PF07554; match to protein family HMM TIGR01167; endo-beta-N-acetylglucosaminidase 446342 6478911 SPG_0451 Streptococcus pneumoniae G54 endo-beta-N-acetylglucosaminidase YP_002037166.1 444990 D 512566 CDS YP_002037167.1 194397815 6480365 446432..447628 1 NC_011072.1 Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway; phosphoglycerate kinase 447628 pgk 6480365 pgk Streptococcus pneumoniae G54 phosphoglycerate kinase YP_002037167.1 446432 D 512566 CDS YP_002037168.1 194397677 6480752 complement(447906..448247) 1 NC_011072.1 IS1380-Spn1 transposase 448247 6480752 SPG_0453 Streptococcus pneumoniae G54 IS1380-Spn1 transposase YP_002037168.1 447906 R 512566 CDS YP_002037169.1 194397065 6478837 complement(448222..449121) 1 NC_011072.1 identified by match to protein family HMM PF01609; IS1380-Spn1 transposase 449121 6478837 SPG_0454 Streptococcus pneumoniae G54 IS1380-Spn1 transposase YP_002037169.1 448222 R 512566 CDS YP_002037170.1 194397085 6479749 complement(449093..449278) 1 NC_011072.1 IS1380-Spn1 transposase 449278 6479749 SPG_0455 Streptococcus pneumoniae G54 IS1380-Spn1 transposase YP_002037170.1 449093 R 512566 CDS YP_002037171.1 194398627 6479680 449498..450025 1 NC_011072.1 hypothetical protein 450025 6479680 SPG_0456 Streptococcus pneumoniae G54 hypothetical protein YP_002037171.1 449498 D 512566 CDS YP_002037172.1 194398030 6478682 450102..450458 1 NC_011072.1 identified by match to protein family HMM PF00376; HTH-type transcriptional regulator GlnR 450458 glnR 6478682 glnR Streptococcus pneumoniae G54 HTH-type transcriptional regulator GlnR YP_002037172.1 450102 D 512566 CDS YP_002037173.1 194396896 6478869 450495..451841 1 NC_011072.1 identified by match to protein family HMM PF00120; match to protein family HMM PF03951; match to protein family HMM TIGR00653; type I glutamine synthetase 451841 glnA 6478869 glnA Streptococcus pneumoniae G54 type I glutamine synthetase YP_002037173.1 450495 D 512566 CDS YP_002037174.1 194396753 6479032 452021..452170 1 NC_011072.1 identified by glimmer; putative; hypothetical protein 452170 6479032 SPG_0459 Streptococcus pneumoniae G54 hypothetical protein YP_002037174.1 452021 D 512566 CDS YP_002037175.1 194398404 6480318 452623..453921 1 NC_011072.1 identified by match to protein family HMM PF01420; type I restriction-modification system subunit S 453921 6480318 SPG_0460 Streptococcus pneumoniae G54 type I restriction-modification system subunit S YP_002037175.1 452623 D 512566 CDS YP_002037176.1 194397904 6479723 complement(454332..455426) 1 NC_011072.1 identified by match to protein family HMM PF01420; Type I restriction modification DNA specificity domain 455426 6479723 SPG_0461 Streptococcus pneumoniae G54 Type I restriction modification DNA specificity domain YP_002037176.1 454332 R 512566 CDS YP_002037177.1 194397534 6479512 complement(455426..456889) 1 NC_011072.1 identified by match to protein family HMM PF02384; match to protein family HMM PF05175; type I restriction-modification system subunit M 456889 6479512 SPG_0462 Streptococcus pneumoniae G54 type I restriction-modification system subunit M YP_002037177.1 455426 R 512566 CDS YP_002037178.1 194396709 6478790 complement(456902..459235) 1 NC_011072.1 identified by match to protein family HMM PF00270; match to protein family HMM PF04313; match to protein family HMM PF04851; match to protein family HMM PF08463; type I restriction-modification system subunit R 459235 6478790 SPG_0463 Streptococcus pneumoniae G54 type I restriction-modification system subunit R YP_002037178.1 456902 R 512566 CDS YP_002037179.1 194398503 6480190 complement(459585..459713) 1 NC_011072.1 hypothetical protein 459713 6480190 SPG_0464 Streptococcus pneumoniae G54 hypothetical protein YP_002037179.1 459585 R 512566 CDS YP_002037180.1 194398682 6480475 459920..460351 1 NC_011072.1 hypothetical protein 460351 6480475 SPG_0465 Streptococcus pneumoniae G54 hypothetical protein YP_002037180.1 459920 D 512566 CDS YP_002037181.1 194397298 6479559 460515..461549 1 NC_011072.1 Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons; heat-inducible transcription repressor 461549 hrcA 6479559 hrcA Streptococcus pneumoniae G54 heat-inducible transcription repressor YP_002037181.1 460515 D 512566 CDS YP_002037182.1 194397486 6478712 461576..462100 1 NC_011072.1 with DnaK and DnaJ acts in response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins; may act as a thermosensor; heat shock protein GrpE 462100 grpE 6478712 grpE Streptococcus pneumoniae G54 heat shock protein GrpE YP_002037182.1 461576 D 512566 CDS YP_002037183.1 194397150 6480525 462580..464403 1 NC_011072.1 heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria; molecular chaperone DnaK 464403 dnaK 6480525 dnaK Streptococcus pneumoniae G54 molecular chaperone DnaK YP_002037183.1 462580 D 512566 CDS YP_002037184.1 194397223 6480236 465033..466169 1 NC_011072.1 chaperone Hsp40; co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion; chaperone protein DnaJ 466169 dnaJ 6480236 dnaJ Streptococcus pneumoniae G54 chaperone protein DnaJ YP_002037184.1 465033 D 512566 CDS YP_002037185.1 194396887 6480572 complement(466536..466823) 1 NC_011072.1 hypothetical protein 466823 6480572 SPG_0470 Streptococcus pneumoniae G54 hypothetical protein YP_002037185.1 466536 R 512566 CDS YP_002037186.1 194397349 6479404 complement(466833..467243) 1 NC_011072.1 identified by match to protein family HMM PF01230; histidine triad domain-containing protein 467243 6479404 SPG_0471 Streptococcus pneumoniae G54 histidine triad domain-containing protein YP_002037186.1 466833 R 512566 CDS YP_002037187.1 194396907 6480358 467311..468042 1 NC_011072.1 identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 468042 6480358 SPG_0472 Streptococcus pneumoniae G54 ABC transporter ATP-binding protein YP_002037187.1 467311 D 512566 CDS YP_002037188.1 194398435 6479812 468039..469088 1 NC_011072.1 identified by match to protein family HMM PF05975; ABC transporter permease 469088 6479812 SPG_0473 Streptococcus pneumoniae G54 ABC transporter permease YP_002037188.1 468039 D 512566 CDS YP_002037189.1 194397728 6480266 complement(469256..469585) 1 NC_011072.1 De Saizieu, A.; 2000 J.Bact 182:4696-4703; BlpT protein 469585 blpT 6480266 blpT Streptococcus pneumoniae G54 BlpT protein YP_002037189.1 469256 R 512566 CDS YP_002037190.1 194397727 6480803 469862..470200 1 NC_011072.1 De Saizieu, A.; 2000 J.Bact 182:4696-4703; identified by match to protein family HMM PF04397; BlpS protein 470200 blpS 6480803 blpS Streptococcus pneumoniae G54 BlpS protein YP_002037190.1 469862 D 512566 CDS YP_002037191.1 194397137 6480802 470205..470942 1 NC_011072.1 de Saizieu A J Bacteriol. 2000 Sep;182(17):4696-703.; identified by match to protein family HMM PF00072; match to protein family HMM PF04397; BlpR response regulator TCS13 470942 blpR 6480802 blpR Streptococcus pneumoniae G54 BlpR response regulator TCS13 YP_002037191.1 470205 D 512566 CDS YP_002037192.1 194398732 6479862 470956..472296 1 NC_011072.1 de Saizieu A J Bacteriol. 2000 Sep;182(17):4696-703.; identified by match to protein family HMM PF02518; BlpH histidine kinase TCS13 472296 blpH 6479862 blpH Streptococcus pneumoniae G54 BlpH histidine kinase TCS13 YP_002037192.1 470956 D 512566 CDS YP_002037193.1 194397991 6478978 complement(472367..472495) 1 NC_011072.1 De Saizieu, A.; 2000 J.Bact 182:4696-4703; identified by match to protein family HMM PF08128; match to protein family HMM TIGR01847; bacteriocin BlpC 472495 blpC 6478978 blpC Streptococcus pneumoniae G54 bacteriocin BlpC YP_002037193.1 472367 R 512566 CDS YP_002037194.1 194398189 6478771 complement(472552..473913) 1 NC_011072.1 De Saizieu, A.; 2000 J.Bact 182:4696-4703; identified by match to protein family HMM TIGR01000; BlpC ABC transporter 473913 blpB 6478771 blpB Streptococcus pneumoniae G54 BlpC ABC transporter YP_002037194.1 472552 R 512566 CDS YP_002037195.1 194398624 6480344 complement(473924..476077) 1 NC_011072.1 De Saizieu, A.; 2000 J.Bact 182:4696-4703; identified by match to protein family HMM PF00005; match to protein family HMM PF00664; match to protein family HMM PF03412; match to protein family HMM TIGR01193; ABC transporter ATP-binding protein BlpA 476077 blpA 6480344 blpA Streptococcus pneumoniae G54 ABC transporter ATP-binding protein BlpA YP_002037195.1 473924 R 512566 CDS YP_002037196.1 194397786 6479533 476358..476561 1 NC_011072.1 bacteriocin BlpPQ 476561 blpPQ 6479533 blpPQ Streptococcus pneumoniae G54 bacteriocin BlpPQ YP_002037196.1 476358 D 512566 CDS YP_002037197.1 194398267 6479966 476879..477082 1 NC_011072.1 identified by glimmer; putative; hypothetical protein 477082 6479966 SPG_0482 Streptococcus pneumoniae G54 hypothetical protein YP_002037197.1 476879 D 512566 CDS YP_002037198.1 194397664 6479592 477656..477820 1 NC_011072.1 hypothetical protein 477820 6479592 SPG_0483 Streptococcus pneumoniae G54 hypothetical protein YP_002037198.1 477656 D 512566 CDS YP_002037199.1 194398009 6479594 478116..478487 1 NC_011072.1 IS1381 transposase OrfA 478487 6479594 SPG_0484 Streptococcus pneumoniae G54 IS1381 transposase OrfA YP_002037199.1 478116 D 512566 CDS YP_002037200.1 194398614 6479329 478575..478874 1 NC_011072.1 IS1381 transposase OrfB 478874 6479329 SPG_0485 Streptococcus pneumoniae G54 IS1381 transposase OrfB YP_002037200.1 478575 D 512566 CDS YP_002037201.1 194396809 6478902 479024..479278 1 NC_011072.1 De Saizieu, A.; 2000 J.Bact 182:4696-4703; identified by match to protein family HMM TIGR01847; bacteriocin BlpM 479278 blpM 6478902 blpM Streptococcus pneumoniae G54 bacteriocin BlpM YP_002037201.1 479024 D 512566 CDS YP_002037202.1 194397403 6479800 479294..479497 1 NC_011072.1 De Saizieu, A.; 2000 J.Bact 182:4696-4703; bacteriocin BlpN 479497 blpN 6479800 blpN Streptococcus pneumoniae G54 bacteriocin BlpN YP_002037202.1 479294 D 512566 CDS YP_002037203.1 194398692 6480154 479516..479725 1 NC_011072.1 bacteriocin Blp 479725 6480154 SPG_0488 Streptococcus pneumoniae G54 bacteriocin Blp YP_002037203.1 479516 D 512566 CDS YP_002037204.1 194397747 6479433 479741..479890 1 NC_011072.1 De Saizieu, A.; 2000 J.Bact 182:4696-4703; identified by match to protein family HMM TIGR01847; bacteriocin BlpO 479890 blpO 6479433 blpO Streptococcus pneumoniae G54 bacteriocin BlpO YP_002037204.1 479741 D 512566 CDS YP_002037205.1 194397187 6480717 479872..479991 1 NC_011072.1 hypothetical protein 479991 6480717 SPG_0490 Streptococcus pneumoniae G54 hypothetical protein YP_002037205.1 479872 D 512566 CDS YP_002037206.1 194397941 6479518 479994..480113 1 NC_011072.1 hypothetical protein 480113 6479518 SPG_0491 Streptococcus pneumoniae G54 hypothetical protein YP_002037206.1 479994 D 512566 CDS YP_002037207.1 194397356 6479491 480899..481282 1 NC_011072.1 De Saizieu, A.; 2000 J.Bact 182:4696-4703; immunity protein BlpX 481282 blpX 6479491 blpX Streptococcus pneumoniae G54 immunity protein BlpX YP_002037207.1 480899 D 512566 CDS YP_002037208.1 194396891 6480398 481334..482023 1 NC_011072.1 De Saizieu, A.; 2000 J.Bact 182:4696-4703; identified by match to protein family HMM PF02517; immunity protein BlpY 482023 6480398 SPG_0493 Streptococcus pneumoniae G54 immunity protein BlpY YP_002037208.1 481334 D 512566 CDS YP_002037209.1 194398332 6479143 482065..482313 1 NC_011072.1 De Saizieu, A.; 2000 J.Bact 182:4696-4703; BlpZ protein 482313 blpZ 6479143 blpZ Streptococcus pneumoniae G54 BlpZ protein YP_002037209.1 482065 D 512566 CDS YP_002037210.1 194397825 6480824 482343..482954 1 NC_011072.1 identified by match to protein family HMM PF02517; CAAX amino terminal protease family 482954 6480824 SPG_0495 Streptococcus pneumoniae G54 CAAX amino terminal protease family YP_002037210.1 482343 D 512566 CDS YP_002037211.1 194398011 6480603 483115..483909 1 NC_011072.1 identified by match to protein family HMM PF01636; phosphotransferase enzyme family protein 483909 6480603 SPG_0496 Streptococcus pneumoniae G54 phosphotransferase enzyme family protein YP_002037211.1 483115 D 512566 CDS YP_002037212.1 194397711 6479439 483906..484541 1 NC_011072.1 tRNA (guanine-N(7)-)-methyltransferase; catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA by transferring the methyl residue from S-adenosyl-L-methionine; tRNA (guanine-N(7)-)-methyltransferase 484541 trmB 6479439 trmB Streptococcus pneumoniae G54 tRNA (guanine-N(7)-)-methyltransferase YP_002037212.1 483906 D 512566 CDS YP_002037213.1 194396782 6480656 484667..485146 1 NC_011072.1 in Streptococcus pneumoniae this gene was found to be essential; structure determination of the Streptococcus protein shows that it is similar to a number of other proteins; hypothetical protein 485146 6480656 SPG_0498 Streptococcus pneumoniae G54 hypothetical protein YP_002037213.1 484667 D 512566 CDS YP_002037214.1 194398628 6479707 485190..486326 1 NC_011072.1 modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination; transcription elongation factor NusA 486326 nusA 6479707 nusA Streptococcus pneumoniae G54 transcription elongation factor NusA YP_002037214.1 485190 D 512566 CDS YP_002037215.1 194396883 6479620 486348..486641 1 NC_011072.1 identified by match to protein family HMM PF04296; hypothetical protein 486641 6479620 SPG_0500 Streptococcus pneumoniae G54 hypothetical protein YP_002037215.1 486348 D 512566 CDS YP_002037216.1 194398582 6479201 486634..486933 1 NC_011072.1 identified by match to protein family HMM PF01248; hypothetical protein 486933 6479201 SPG_0501 Streptococcus pneumoniae G54 hypothetical protein YP_002037216.1 486634 D 512566 CDS YP_002037217.1 194398729 6478715 486950..489742 1 NC_011072.1 Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; translation initiation factor IF-2 489742 infB 6478715 infB Streptococcus pneumoniae G54 translation initiation factor IF-2 YP_002037217.1 486950 D 512566 CDS YP_002037218.1 194397934 6479582 489993..490343 1 NC_011072.1 associates with free 30S ribosomal subunits; essential for efficient processing of 16S rRNA; in Escherichia coli rbfA is induced by cold shock; ribosome-binding factor A 490343 rbfA 6479582 rbfA Streptococcus pneumoniae G54 ribosome-binding factor A YP_002037218.1 489993 D 512566 CDS YP_002037219.1 194397202 6478916 490631..491977 1 NC_011072.1 identified by match to protein family HMM PF01609; IS1380-Spn1 transposase 491977 6478916 SPG_0504 Streptococcus pneumoniae G54 IS1380-Spn1 transposase YP_002037219.1 490631 D 512566 CDS YP_002037220.1 194397500 6480772 492330..493109 1 NC_011072.1 hypothetical protein 493109 6480772 SPG_0505 Streptococcus pneumoniae G54 hypothetical protein YP_002037220.1 492330 D 512566 CDS YP_002037221.1 194397022 6478848 493180..493293 1 NC_011072.1 hypothetical protein 493293 6478848 SPG_0506 Streptococcus pneumoniae G54 hypothetical protein YP_002037221.1 493180 D 512566 CDS YP_002037222.1 194398683 6479896 493290..493442 1 NC_011072.1 identified by glimmer; putative; hypothetical protein 493442 6479896 SPG_0507 Streptococcus pneumoniae G54 hypothetical protein YP_002037222.1 493290 D 512566 CDS YP_002037223.1 194397237 6479560 493755..493988 1 NC_011072.1 identified by match to protein family HMM PF08984; hypothetical protein 493988 6479560 SPG_0508 Streptococcus pneumoniae G54 hypothetical protein YP_002037223.1 493755 D 512566 CDS YP_002037224.1 194396768 6480321 493988..495322 1 NC_011072.1 identified by match to protein family HMM PF01814; match to protein family HMM PF04282; hypothetical protein 495322 6480321 SPG_0509 Streptococcus pneumoniae G54 hypothetical protein YP_002037224.1 493988 D 512566 CDS YP_002037225.1 194397597 6480222 495332..495586 1 NC_011072.1 identified by glimmer; putative; hypothetical protein 495586 6480222 SPG_0510 Streptococcus pneumoniae G54 hypothetical protein YP_002037225.1 495332 D 512566 CDS YP_002037226.1 194398312 6478795 495682..495855 1 NC_011072.1 hypothetical protein 495855 6478795 SPG_0511 Streptococcus pneumoniae G54 hypothetical protein YP_002037226.1 495682 D 512566 CDS YP_002037227.1 194397309 6479022 495915..496076 1 NC_011072.1 hypothetical protein 496076 6479022 SPG_0512 Streptococcus pneumoniae G54 hypothetical protein YP_002037227.1 495915 D 512566 CDS YP_002037228.1 194397762 6478660 496620..496937 1 NC_011072.1 identified by glimmer; putative; hypothetical protein 496937 6478660 SPG_0513 Streptococcus pneumoniae G54 hypothetical protein YP_002037228.1 496620 D 512566 CDS YP_002037229.1 194398541 6479714 496924..497484 1 NC_011072.1 identified by match to protein family HMM PF00583; GNAT family acetyltransferase 497484 6479714 SPG_0514 Streptococcus pneumoniae G54 GNAT family acetyltransferase YP_002037229.1 496924 D 512566 CDS YP_002037230.1 194396807 6480621 497484..498062 1 NC_011072.1 identified by glimmer; putative; hypothetical protein 498062 6480621 SPG_0515 Streptococcus pneumoniae G54 hypothetical protein YP_002037230.1 497484 D 512566 CDS YP_002037231.1 194398081 6479302 498055..500706 1 NC_011072.1 valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain; valyl-tRNA synthetase 500706 valS 6479302 valS Streptococcus pneumoniae G54 valyl-tRNA synthetase YP_002037231.1 498055 D 512566 CDS YP_002037232.1 194398572 6479460 500776..501072 1 NC_011072.1 contains potential frameshift; hypothetical protein 501072 6479460 SPG_0517 Streptococcus pneumoniae G54 hypothetical protein YP_002037232.1 500776 D 512566 CDS YP_002037233.1 194397144 6479151 501171..501530 1 NC_011072.1 contains potential frameshift; hypothetical protein 501530 6479151 SPG_0518 Streptococcus pneumoniae G54 hypothetical protein YP_002037233.1 501171 D 512566 CDS YP_002037234.1 194397647 6480114 501809..502612 1 NC_011072.1 identified by match to protein family HMM PF02661; cell filamentation protein Fic-related protein 502612 6480114 SPG_0519 Streptococcus pneumoniae G54 cell filamentation protein Fic-related protein YP_002037234.1 501809 D 512566 CDS YP_002037235.1 194398100 6478843 complement(502728..502946) 1 NC_011072.1 IS3-Spn1 transposase 502946 6478843 SPG_0520 Streptococcus pneumoniae G54 IS3-Spn1 transposase YP_002037235.1 502728 R 512566 CDS YP_002037236.1 194397094 6480509 complement(503224..503553) 1 NC_011072.1 IS3-Spn1 transposase 503553 6480509 SPG_0521 Streptococcus pneumoniae G54 IS3-Spn1 transposase YP_002037236.1 503224 R 512566 CDS YP_002037237.1 194397695 6480544 complement(503553..503720) 1 NC_011072.1 degenarate transposase 503720 6480544 SPG_0522 Streptococcus pneumoniae G54 degenarate transposase YP_002037237.1 503553 R 512566 CDS YP_002037238.1 194398016 6479449 complement(503857..504069) 1 NC_011072.1 IS3-Spn1 transposase 504069 6479449 SPG_0523 Streptococcus pneumoniae G54 IS3-Spn1 transposase YP_002037238.1 503857 R 512566 CDS YP_002037239.1 194398641 6479273 504611..505450 1 NC_011072.1 identified by match to protein family HMM PF00874; match to protein family HMM PF03123; transcription antiterminator LicT 505450 licT 6479273 licT Streptococcus pneumoniae G54 transcription antiterminator LicT YP_002037239.1 504611 D 512566 CDS YP_002037240.1 194397360 6479078 505468..507306 1 NC_011072.1 identified by match to protein family HMM PF00358; match to protein family HMM PF00367; match to protein family HMM PF02378; match to protein family HMM TIGR00830; match to protein family HMM TIGR01995; PTS system transporter subunit IIBCA 507306 6479078 SPG_0525 Streptococcus pneumoniae G54 PTS system transporter subunit IIBCA YP_002037240.1 505468 D 512566 CDS YP_002037241.1 194397947 6480694 507319..508734 1 NC_011072.1 identified by match to protein family HMM PF00232; beta-glucosidase 508734 6480694 SPG_0526 Streptococcus pneumoniae G54 beta-glucosidase YP_002037241.1 507319 D 512566 CDS YP_002037242.1 194398363 6479187 509284..510372 1 NC_011072.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily; phenylalanyl-tRNA synthetase subunit alpha 510372 pheS 6479187 pheS Streptococcus pneumoniae G54 phenylalanyl-tRNA synthetase subunit alpha YP_002037242.1 509284 D 512566 CDS YP_002037243.1 194396724 6480111 510372..510869 1 NC_011072.1 identified by match to protein family HMM PF00583; GNAT family acetyltransferase 510869 6480111 SPG_0528 Streptococcus pneumoniae G54 GNAT family acetyltransferase YP_002037243.1 510372 D 512566 CDS YP_002037244.1 194397698 6480019 510946..513351 1 NC_011072.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily; phenylalanyl-tRNA synthetase subunit beta 513351 pheT 6480019 pheT Streptococcus pneumoniae G54 phenylalanyl-tRNA synthetase subunit beta YP_002037244.1 510946 D 512566 CDS YP_002037245.1 194397749 6479530 complement(513419..514426) 1 NC_011072.1 identified by match to protein family HMM PF03372; hypothetical protein 514426 6479530 SPG_0530 Streptococcus pneumoniae G54 hypothetical protein YP_002037245.1 513419 R 512566 CDS YP_002037246.1 194398418 6479998 514582..514806 1 NC_011072.1 IS1239, transposase 514806 6479998 SPG_0531 Streptococcus pneumoniae G54 IS1239, transposase YP_002037246.1 514582 D 512566 CDS YP_002037247.1 194397736 6480487 514869..514988 1 NC_011072.1 transposase 514988 6480487 SPG_0532 Streptococcus pneumoniae G54 transposase YP_002037247.1 514869 D 512566 CDS YP_002037248.1 194398199 6480439 515110..515376 1 NC_011072.1 contains potential frameshift; identified by match to protein family HMM PF01381; hypothetical protein 515376 6480439 SPG_0533 Streptococcus pneumoniae G54 hypothetical protein YP_002037248.1 515110 D 512566 CDS YP_002037249.1 194397595 6478777 515637..517886 1 NC_011072.1 catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine to form methionine; 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase 517886 6478777 SPG_0534 Streptococcus pneumoniae G54 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase YP_002037249.1 515637 D 512566 CDS YP_002037250.1 194396941 6479221 517950..518816 1 NC_011072.1 identified by match to protein family HMM PF02219; match to protein family HMM TIGR00676; 5,10-methylenetetrahydrofolate reductase 518816 metF 6479221 metF Streptococcus pneumoniae G54 5,10-methylenetetrahydrofolate reductase YP_002037250.1 517950 D 512566 CDS YP_002037251.1 194398464 6479793 519501..521714 1 NC_011072.1 identified by match to protein family HMM PF00013; match to protein family HMM PF00575; match to protein family HMM PF01138; match to protein family HMM PF03725; match to protein family HMM PF03726; polynucleotide phosphorylase/polyadenylase 521714 6479793 SPG_0536 Streptococcus pneumoniae G54 polynucleotide phosphorylase/polyadenylase YP_002037251.1 519501 D 512566 CDS YP_002037252.1 194397898 6479933 521730..522347 1 NC_011072.1 identified by match to protein family HMM TIGR01172; serine O-acetyltransferase 522347 cysE 6479933 cysE Streptococcus pneumoniae G54 serine O-acetyltransferase YP_002037252.1 521730 D 512566 CDS YP_002037253.1 194397307 6478811 522359..523243 1 NC_011072.1 identified by match to protein family HMM PF00583; GNAT family acetyltransferase 523243 6478811 SPG_0538 Streptococcus pneumoniae G54 GNAT family acetyltransferase YP_002037253.1 522359 D 512566 CDS YP_002037254.1 194396665 6479543 523325..524668 1 NC_011072.1 catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA; cysteinyl-tRNA synthetase 524668 cysS 6479543 cysS Streptococcus pneumoniae G54 cysteinyl-tRNA synthetase YP_002037254.1 523325 D 512566 CDS YP_002037255.1 194398019 6479787 524661..525047 1 NC_011072.1 identified by match to protein family HMM PF00636; hypothetical protein 525047 6479787 SPG_0540 Streptococcus pneumoniae G54 hypothetical protein YP_002037255.1 524661 D 512566 CDS YP_002037256.1 194396851 6478789 525051..525935 1 NC_011072.1 identified by glimmer; putative; hypothetical protein 525935 6478789 SPG_0541 Streptococcus pneumoniae G54 hypothetical protein YP_002037256.1 525051 D 512566 CDS YP_002037257.1 194398278 6479558 526072..526671 1 NC_011072.1 hypothetical protein 526671 6479558 SPG_0542 Streptococcus pneumoniae G54 hypothetical protein YP_002037257.1 526072 D 512566 CDS YP_002037258.1 194397804 6478708 526817..526987 1 NC_011072.1 putative group II intron protein 526987 6478708 SPG_0543 Streptococcus pneumoniae G54 putative group II intron protein YP_002037258.1 526817 D 512566 CDS YP_002037259.1 194397313 6480243 527340..528617 1 NC_011072.1 identified by match to protein family HMM PF02687; ABC transporter permease 528617 6480243 SPG_0544 Streptococcus pneumoniae G54 ABC transporter permease YP_002037259.1 527340 D 512566 CDS YP_002037260.1 194396840 6479524 528630..529277 1 NC_011072.1 identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 529277 6479524 SPG_0545 Streptococcus pneumoniae G54 ABC transporter ATP-binding protein YP_002037260.1 528630 D 512566 CDS YP_002037261.1 194398041 6479428 529329..530708 1 NC_011072.1 identified by match to protein family HMM PF02687; ABC transporter permease 530708 6479428 SPG_0546 Streptococcus pneumoniae G54 ABC transporter permease YP_002037261.1 529329 D 512566 CDS YP_002037262.1 194397670 6479506 531020..531676 1 NC_011072.1 Haas W J Bacteriol. 2004 186(24):8463-71.; identified by match to protein family HMM PF00072; match to protein family HMM PF00486; VncR response regulator TCS10 531676 vncR 6479506 vncR Streptococcus pneumoniae G54 VncR response regulator TCS10 YP_002037262.1 531020 D 512566 CDS YP_002037263.1 194397061 6479569 531673..533001 1 NC_011072.1 Haas W J Bacteriol. 2004 186(24):8463-71.; identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518; VncS histidine kinase TCS10 533001 vncS 6479569 vncS Streptococcus pneumoniae G54 VncS histidine kinase TCS10 YP_002037263.1 531673 D 512566 CDS YP_002037264.1 194398346 6480256 533142..534023 1 NC_011072.1 catalyzes the formation of glycerone phosphate and glyceraldehyde 3-phosphate from fructose 1,6, bisphosphate; fructose-bisphosphate aldolase 534023 fba 6480256 fba Streptococcus pneumoniae G54 fructose-bisphosphate aldolase YP_002037264.1 533142 D 512566 CDS YP_002037265.1 194397725 6480407 complement(534345..535535) 1 NC_011072.1 identified by match to protein family HMM PF00175; match to protein family HMM PF00970; match to protein family HMM PF01794; oxidoreductase 535535 6480407 SPG_0550 Streptococcus pneumoniae G54 oxidoreductase YP_002037265.1 534345 R 512566 CDS YP_002037266.1 194397718 6480173 complement(535830..536489) 1 NC_011072.1 identified by match to protein family HMM PF00528; match to protein family HMM TIGR01726; ABC transporter permease 536489 6480173 SPG_0551 Streptococcus pneumoniae G54 ABC transporter permease YP_002037266.1 535830 R 512566 CDS YP_002037267.1 194397213 6480128 complement(536499..537176) 1 NC_011072.1 identified by match to protein family HMM PF00528; match to protein family HMM TIGR01726; ABC transporter permease 537176 6480128 SPG_0552 Streptococcus pneumoniae G54 ABC transporter permease YP_002037267.1 536499 R 512566 CDS YP_002037268.1 194397781 6480279 complement(537189..537983) 1 NC_011072.1 identified by match to protein family HMM PF00497; ABC transporter substrate-binding protein 537983 6480279 SPG_0553 Streptococcus pneumoniae G54 ABC transporter substrate-binding protein YP_002037268.1 537189 R 512566 CDS YP_002037269.1 194398146 6479699 complement(537994..538752) 1 NC_011072.1 identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 538752 6479699 SPG_0554 Streptococcus pneumoniae G54 ABC transporter ATP-binding protein YP_002037269.1 537994 R 512566 CDS YP_002037270.1 194398716 6479624 539029..541251 1 NC_011072.1 identified by match to protein family HMM PF01368; match to protein family HMM PF02272; match to protein family HMM TIGR00644; single-stranded-DNA-specific exonuclease RecJ 541251 recJ 6479624 recJ Streptococcus pneumoniae G54 single-stranded-DNA-specific exonuclease RecJ YP_002037270.1 539029 D 512566 CDS YP_002037271.1 194397551 6478806 541426..543087 1 NC_011072.1 identified by match to protein family HMM PF00753; match to protein family HMM PF07521; hypothetical protein 543087 6478806 SPG_0556 Streptococcus pneumoniae G54 hypothetical protein YP_002037271.1 541426 D 512566 CDS YP_002037272.1 194397975 6479287 543156..543935 1 NC_011072.1 identified by match to protein family HMM PF00756; esterase 543935 6479287 SPG_0557 Streptococcus pneumoniae G54 esterase YP_002037272.1 543156 D 512566 CDS YP_002037273.1 194398661 6479474 544047..545267 1 NC_011072.1 identified by match to protein family HMM PF02388; serine/alanine-adding enzyme MurM 545267 6479474 SPG_0558 Streptococcus pneumoniae G54 serine/alanine-adding enzyme MurM YP_002037273.1 544047 D 512566 CDS YP_002037274.1 194396995 6478716 545272..546504 1 NC_011072.1 identified by match to protein family HMM PF02388; alanine adding enzyme 546504 6478716 SPG_0559 Streptococcus pneumoniae G54 alanine adding enzyme YP_002037274.1 545272 D 512566 CDS YP_002037275.1 194397829 6479960 546583..547284 1 NC_011072.1 identified by match to protein family HMM PF00413; hypothetical protein 547284 6479960 SPG_0560 Streptococcus pneumoniae G54 hypothetical protein YP_002037275.1 546583 D 512566 CDS YP_002037276.1 194398570 6480458 547324..549171 1 NC_011072.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision; excinuclease ABC subunit C 549171 uvrC 6480458 uvrC Streptococcus pneumoniae G54 excinuclease ABC subunit C YP_002037276.1 547324 D 512566 CDS YP_002037277.1 194398325 6479285 549221..549994 1 NC_011072.1 hypothetical protein 549994 6479285 SPG_0562 Streptococcus pneumoniae G54 hypothetical protein YP_002037277.1 549221 D 512566 CDS YP_002037278.1 194397854 6479493 complement(550176..550976) 1 NC_011072.1 identified by match to protein family HMM PF00497; ABC transporter substrate-binding protein 550976 6479493 SPG_0563 Streptococcus pneumoniae G54 ABC transporter substrate-binding protein YP_002037278.1 550176 R 512566 CDS YP_002037279.1 194397345 6480261 551147..551302 1 NC_011072.1 contains potential frameshift; nitroreductase 551302 6480261 SPG_0564 Streptococcus pneumoniae G54 nitroreductase YP_002037279.1 551147 D 512566 CDS YP_002037280.1 194396870 6480583 551325..551753 1 NC_011072.1 contains potential frameshift; identified by match to protein family HMM PF00881; nitroreductase 551753 6480583 SPG_0565 Streptococcus pneumoniae G54 nitroreductase YP_002037280.1 551325 D 512566 CDS YP_002037281.1 194396862 6478687 551766..553166 1 NC_011072.1 divalent metal ion-dependent extracellular dipeptidase; able to hydrolyze a broad range of dipeptides but no tri-, tetra-, or larger oligopeptides; differences in the amino acid specificity of the cleavage site varies between species; similar to succinyl-diaminopimelate desuccinylases; dipeptidase PepV 553166 6478687 SPG_0566 Streptococcus pneumoniae G54 dipeptidase PepV YP_002037281.1 551766 D 512566 CDS YP_002037282.1 194398008 6479450 553220..553798 1 NC_011072.1 identified by match to protein family HMM PF03167; hypothetical protein 553798 6479450 SPG_0567 Streptococcus pneumoniae G54 hypothetical protein YP_002037282.1 553220 D 512566 CDS YP_002037283.1 194397587 6479025 553958..554110 1 NC_011072.1 hypothetical protein 554110 6479025 SPG_0568 Streptococcus pneumoniae G54 hypothetical protein YP_002037283.1 553958 D 512566 CDS YP_002037284.1 194397040 6478952 554111..554245 1 NC_011072.1 hypothetical protein 554245 6478952 SPG_0569 Streptococcus pneumoniae G54 hypothetical protein YP_002037284.1 554111 D 512566 CDS YP_002037285.1 194397164 6479798 554416..555741 1 NC_011072.1 identified by match to protein family HMM PF05525; match to protein family HMM TIGR00796; branched-chain amino acid transport protein 555741 6479798 SPG_0570 Streptococcus pneumoniae G54 branched-chain amino acid transport protein YP_002037285.1 554416 D 512566 CDS YP_002037286.1 194397526 6479136 555839..556876 1 NC_011072.1 identified by match to protein family HMM PF05343; hypothetical protein 556876 6479136 SPG_0571 Streptococcus pneumoniae G54 hypothetical protein YP_002037286.1 555839 D 512566 CDS YP_002037287.1 194397857 6479084 556878..557339 1 NC_011072.1 identified by match to protein family HMM PF01230; histidine triad domain-containing protein 557339 6479084 SPG_0572 Streptococcus pneumoniae G54 histidine triad domain-containing protein YP_002037287.1 556878 D 512566 CDS YP_002037288.1 194398047 6480100 557365..558081 1 NC_011072.1 identified by match to protein family HMM PF02557; D-alanyl-D-alanine carboxypeptidase 558081 6480100 SPG_0573 Streptococcus pneumoniae G54 D-alanyl-D-alanine carboxypeptidase YP_002037288.1 557365 D 512566 CDS YP_002037289.1 194398635 6479480 558390..558815 1 NC_011072.1 binds directly to 23S ribosomal RNA; 50S ribosomal protein L11 558815 rplK 6479480 rplK Streptococcus pneumoniae G54 50S ribosomal protein L11 YP_002037289.1 558390 D 512566 CDS YP_002037290.1 194397100 6479390 559023..559712 1 NC_011072.1 in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA; 50S ribosomal protein L1 559712 rplA 6479390 rplA Streptococcus pneumoniae G54 50S ribosomal protein L1 YP_002037290.1 559023 D 512566 CDS YP_002037291.1 194398185 6480704 complement(559801..560328) 1 NC_011072.1 IS1167 transposase 560328 6480704 SPG_0576 Streptococcus pneumoniae G54 IS1167 transposase YP_002037291.1 559801 R 512566 CDS YP_002037292.1 194398743 6480289 complement(560609..561127) 1 NC_011072.1 IS1167 transposase 561127 6480289 SPG_0577 Streptococcus pneumoniae G54 IS1167 transposase YP_002037292.1 560609 R 512566 CDS YP_002037293.1 194397337 6479213 562049..562267 1 NC_011072.1 hypothetical protein 562267 6479213 SPG_0578 Streptococcus pneumoniae G54 hypothetical protein YP_002037293.1 562049 D 512566 CDS YP_002037294.1 194397346 6480543 563311..564303 1 NC_011072.1 identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 564303 6480543 SPG_0579 Streptococcus pneumoniae G54 ABC transporter ATP-binding protein YP_002037294.1 563311 D 512566 CDS YP_002037295.1 194396937 6480584 564305..565123 1 NC_011072.1 identified by match to protein family HMM PF06182; ABC transporter permease 565123 6480584 SPG_0580 Streptococcus pneumoniae G54 ABC transporter permease YP_002037295.1 564305 D 512566 CDS YP_002037296.1 194397192 6480038 565125..565910 1 NC_011072.1 identified by match to protein family HMM PF06182; ABC transporter permease 565910 6480038 SPG_0581 Streptococcus pneumoniae G54 ABC transporter permease YP_002037296.1 565125 D 512566 CDS YP_002037297.1 194396751 6478747 565949..566227 1 NC_011072.1 identified by glimmer; putative; hypothetical protein 566227 6478747 SPG_0582 Streptococcus pneumoniae G54 hypothetical protein YP_002037297.1 565949 D 512566 CDS YP_002037298.1 194398672 6479703 566212..566409 1 NC_011072.1 hypothetical protein 566409 6479703 SPG_0583 Streptococcus pneumoniae G54 hypothetical protein YP_002037298.1 566212 D 512566 CDS YP_002037299.1 194398239 6478885 567097..573528 1 NC_011072.1 identified by match to protein family HMM PF00082; match to protein family HMM PF00746; match to protein family HMM PF02225; match to protein family HMM PF05922; match to protein family HMM PF06280; match to protein family HMM TIGR01167; serine protease 573528 prtA 6478885 prtA Streptococcus pneumoniae G54 serine protease YP_002037299.1 567097 D 512566 CDS YP_002037300.1 194397170 6479203 574154..574630 1 NC_011072.1 identified by match to protein family HMM PF00359; PTS system transporter subunit IIA 574630 6479203 SPG_0585 Streptococcus pneumoniae G54 PTS system transporter subunit IIA YP_002037300.1 574154 D 512566 CDS YP_002037301.1 194398557 6479252 574668..574973 1 NC_011072.1 PTS system transporter subunit IIB 574973 6479252 SPG_0586 Streptococcus pneumoniae G54 PTS system transporter subunit IIB YP_002037301.1 574668 D 512566 CDS YP_002037302.1 194398407 6479541 575021..576496 1 NC_011072.1 identified by match to protein family HMM PF03611; PTS system transporter subunit IIC 576496 6479541 SPG_0587 Streptococcus pneumoniae G54 PTS system transporter subunit IIC YP_002037302.1 575021 D 512566 CDS YP_002037303.1 194397629 6480768 576846..583547 1 NC_011072.1 identified by match to protein family HMM PF00703; match to protein family HMM PF00746; match to protein family HMM PF02836; match to protein family HMM PF02837; match to protein family HMM PF04650; match to protein family HMM PF07501; match to protein family HMM PF07532; match to protein family HMM TIGR01167; match to protein family HMM TIGR01168; beta-galactosidase 583547 6480768 SPG_0588 Streptococcus pneumoniae G54 beta-galactosidase YP_002037303.1 576846 D 512566 CDS YP_002037304.1 194396797 6479262 complement(583804..584025) 1 NC_011072.1 transposase 584025 6479262 SPG_0589 Streptococcus pneumoniae G54 transposase YP_002037304.1 583804 R 512566 CDS YP_002037305.1 194397232 6480705 complement(583994..584407) 1 NC_011072.1 transposase 584407 6480705 SPG_0590 Streptococcus pneumoniae G54 transposase YP_002037305.1 583994 R 512566 CDS YP_002037306.1 194396729 6480276 complement(584407..584652) 1 NC_011072.1 transposase 584652 6480276 SPG_0591 Streptococcus pneumoniae G54 transposase YP_002037306.1 584407 R 512566 CDS YP_002037307.1 194398445 6480331 complement(584863..585222) 1 NC_011072.1 identified by glimmer; putative; hypothetical protein 585222 6480331 SPG_0592 Streptococcus pneumoniae G54 hypothetical protein YP_002037307.1 584863 R 512566 CDS YP_002037308.1 194397976 6479977 585314..585766 1 NC_011072.1 hypothetical protein 585766 6479977 SPG_0593 Streptococcus pneumoniae G54 hypothetical protein YP_002037308.1 585314 D 512566 CDS YP_002037309.1 194397473 6479475 585824..586270 1 NC_011072.1 identified by glimmer; putative; hypothetical protein 586270 6479475 SPG_0594 Streptococcus pneumoniae G54 hypothetical protein YP_002037309.1 585824 D 512566 CDS YP_002037310.1 194398444 6479636 586254..586811 1 NC_011072.1 identified by match to protein family HMM PF06962; hypothetical protein 586811 6479636 SPG_0595 Streptococcus pneumoniae G54 hypothetical protein YP_002037310.1 586254 D 512566 CDS YP_002037311.1 194398663 6480553 586804..587058 1 NC_011072.1 hypothetical protein 587058 6480553 SPG_0596 Streptococcus pneumoniae G54 hypothetical protein YP_002037311.1 586804 D 512566 CDS YP_002037312.1 194398212 6478718 587070..589124 1 NC_011072.1 identified by match to protein family HMM PF00999; monovalent cation:proton antiporter-2 (CPA2) family transporter 589124 6478718 SPG_0597 Streptococcus pneumoniae G54 monovalent cation:proton antiporter-2 (CPA2) family transporter YP_002037312.1 587070 D 512566 CDS YP_002037313.1 194398139 6478890 589303..590163 1 NC_011072.1 identified by match to protein family HMM PF03631; ribonuclease BN 590163 6478890 SPG_0598 Streptococcus pneumoniae G54 ribonuclease BN YP_002037313.1 589303 D 512566 CDS YP_002037314.1 194397737 6480122 590374..591084 1 NC_011072.1 identified by match to protein family HMM PF02683; cytochrome c-type biogenesis protein CcdA 591084 6480122 SPG_0599 Streptococcus pneumoniae G54 cytochrome c-type biogenesis protein CcdA YP_002037314.1 590374 D 512566 CDS YP_002037315.1 194397635 6480440 591104..591670 1 NC_011072.1 identified by match to protein family HMM PF00578; match to protein family HMM PF08534; thioredoxin family protein 591670 6480440 SPG_0600 Streptococcus pneumoniae G54 thioredoxin family protein YP_002037315.1 591104 D 512566 CDS YP_002037316.1 194397498 6479599 591681..592793 1 NC_011072.1 identified by match to protein family HMM PF01625; match to protein family HMM PF01641; match to protein family HMM TIGR00357; match to protein family HMM TIGR00401; peptide methionine sulfoxide reductase MsrA/msrB 592793 6479599 SPG_0601 Streptococcus pneumoniae G54 peptide methionine sulfoxide reductase MsrA/msrB YP_002037316.1 591681 D 512566 CDS YP_002037317.1 194397419 6478846 593061..593798 1 NC_011072.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00165; response regulator 593798 6478846 SPG_0602 Streptococcus pneumoniae G54 response regulator YP_002037317.1 593061 D 512566 CDS YP_002037318.1 194397006 6479886 593795..595486 1 NC_011072.1 identified by match to protein family HMM PF00672; match to protein family HMM PF02518; match to protein family HMM PF02743; match to protein family HMM PF06580; histidine kinase 595486 6479886 SPG_0603 Streptococcus pneumoniae G54 histidine kinase YP_002037318.1 593795 D 512566 CDS YP_002037319.1 194398698 6480822 595602..596165 1 NC_011072.1 identified by match to protein family HMM PF04260; match to protein family HMM TIGR01440; hypothetical protein 596165 6480822 SPG_0604 Streptococcus pneumoniae G54 hypothetical protein YP_002037319.1 595602 D 512566 CDS YP_002037320.1 194397255 6479105 596187..601799 1 NC_011072.1 identified by match to protein family HMM PF00746; match to protein family HMM PF07501; match to protein family HMM PF07580; match to protein family HMM TIGR01167; zinc metalloprotease ZmpB 601799 zmpB 6479105 zmpB Streptococcus pneumoniae G54 zinc metalloprotease ZmpB YP_002037320.1 596187 D 512566 CDS YP_002037321.1 194396757 6479873 601873..603594 1 NC_011072.1 identified by match to protein family HMM PF00425; match to protein family HMM TIGR00553; para-aminobenzoate synthases component I 603594 6479873 SPG_0606 Streptococcus pneumoniae G54 para-aminobenzoate synthases component I YP_002037321.1 601873 D 512566 CDS YP_002037322.1 194398673 6479869 603595..604212 1 NC_011072.1 hypothetical protein 604212 6479869 SPG_0607 Streptococcus pneumoniae G54 hypothetical protein YP_002037322.1 603595 D 512566 CDS YP_002037323.1 194398225 6478759 604262..605188 1 NC_011072.1 contains potential frameshift; identified by match to protein family HMM PF01473; match to protein family HMM PF05901; choline binding protein 605188 6478759 SPG_0608 Streptococcus pneumoniae G54 choline binding protein YP_002037323.1 604262 D 512566 CDS YP_002037324.1 194397342 6479613 605369..606346 1 NC_011072.1 identified by match to protein family HMM PF00480; match to protein family HMM TIGR00744; glucokinase 606346 gki 6479613 gki Streptococcus pneumoniae G54 glucokinase YP_002037324.1 605369 D 512566 CDS YP_002037325.1 194396733 6480095 606443..607282 1 NC_011072.1 ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived; thymidylate synthase 607282 thyA 6480095 thyA Streptococcus pneumoniae G54 thymidylate synthase YP_002037325.1 606443 D 512566 CDS YP_002037326.1 194398269 6479695 complement(607330..607500) 1 NC_011072.1 hypothetical protein 607500 6479695 SPG_0611 Streptococcus pneumoniae G54 hypothetical protein YP_002037326.1 607330 R 512566 CDS YP_002037327.1 194397782 6478678 607621..608505 1 NC_011072.1 IPP transferase; isopentenyltransferase; involved in tRNA modification; in Escherichia coli this enzyme catalyzes the addition of a delta2-isopentenyl group from dimethylallyl diphosphate to the N6-nitrogen of adenosine adjacent to the anticodon of tRNA species that read codons starting with uracil; further tRNA modifications may occur; mutations in miaA result in defects in translation efficiency and fidelity; tRNA delta(2)-isopentenylpyrophosphate transferase 608505 miaA 6478678 miaA Streptococcus pneumoniae G54 tRNA delta(2)-isopentenylpyrophosphate transferase YP_002037327.1 607621 D 512566 CDS YP_002037328.1 194397324 6480695 608498..609736 1 NC_011072.1 identified by match to protein family HMM PF01926; match to protein family HMM TIGR00231; match to protein family HMM TIGR03156; GTP-binding proten HflX 609736 6480695 SPG_0613 Streptococcus pneumoniae G54 GTP-binding proten HflX YP_002037328.1 608498 D 512566 CDS YP_002037329.1 194396897 6480221 609729..610352 1 NC_011072.1 identified by glimmer; putative; hypothetical protein 610352 6480221 SPG_0614 Streptococcus pneumoniae G54 hypothetical protein YP_002037329.1 609729 D 512566 CDS YP_002037330.1 194397004 6479177 610367..611296 1 NC_011072.1 member of metallo-beta-lactamase family; the purified enzyme from Escherichia coli forms dimeric zinc phosphodiesterase; in Bacillus subtilis this protein is a 3'-tRNA processing endoribonuclease and is essential while in Escherichia coli it is not; associates with two zinc ions; ribonuclease Z 611296 rnz 6479177 rnz Streptococcus pneumoniae G54 ribonuclease Z YP_002037330.1 610367 D 512566 CDS YP_002037331.1 194398670 6479818 611317..612072 1 NC_011072.1 identified by match to protein family HMM PF00106; match to protein family HMM PF08659; short chain dehydrogenase/reductase family oxidoreductase 612072 6479818 SPG_0616 Streptococcus pneumoniae G54 short chain dehydrogenase/reductase family oxidoreductase YP_002037331.1 611317 D 512566 CDS YP_002037332.1 194398295 6478883 complement(612126..613094) 1 NC_011072.1 identified by match to protein family HMM PF00126; transcriptional regulator 613094 6478883 SPG_0617 Streptococcus pneumoniae G54 transcriptional regulator YP_002037332.1 612126 R 512566 CDS YP_002037333.1 194397853 6479054 613098..613367 1 NC_011072.1 identified by match to protein family HMM PF06014; hypothetical protein 613367 6479054 SPG_0618 Streptococcus pneumoniae G54 hypothetical protein YP_002037333.1 613098 D 512566 CDS YP_002037334.1 194397655 6480141 613367..613747 1 NC_011072.1 identified by match to protein family HMM PF00581; rhodanese-like domain 613747 6480141 SPG_0619 Streptococcus pneumoniae G54 rhodanese-like domain YP_002037334.1 613367 D 512566 CDS YP_002037335.1 194398134 6479068 613836..614063 1 NC_011072.1 hypothetical protein 614063 6479068 SPG_0620 Streptococcus pneumoniae G54 hypothetical protein YP_002037335.1 613836 D 512566 CDS YP_002037336.1 194397181 6480325 complement(614103..614828) 1 NC_011072.1 identified by match to protein family HMM PF00849; match to protein family HMM PF01479; match to protein family HMM TIGR00093; ribosomal small subunit pseudouridine synthase A 614828 6480325 SPG_0621 Streptococcus pneumoniae G54 ribosomal small subunit pseudouridine synthase A YP_002037336.1 614103 R 512566 CDS YP_002037337.1 194397528 6479250 614990..615796 1 NC_011072.1 contains potential frameshift; identified by match to protein family HMM PF00009; match to protein family HMM TIGR00231; elongation factor Tu family protein 615796 6479250 SPG_0622 Streptococcus pneumoniae G54 elongation factor Tu family protein YP_002037337.1 614990 D 512566 CDS YP_002037338.1 194398010 6479086 615753..616832 1 NC_011072.1 contains potential frameshift; identified by match to protein family HMM PF00679; elongation factor Tu family protein 616832 6479086 SPG_0623 Streptococcus pneumoniae G54 elongation factor Tu family protein YP_002037338.1 615753 D 512566 CDS YP_002037339.1 194398455 6479330 616852..617106 1 NC_011072.1 hypothetical protein 617106 6479330 SPG_0624 Streptococcus pneumoniae G54 hypothetical protein YP_002037339.1 616852 D 512566 CDS YP_002037340.1 194398297 6480713 617469..617768 1 NC_011072.1 identified by match to protein family HMM TIGR01653; hypothetical protein 617768 6480713 SPG_0625 Streptococcus pneumoniae G54 hypothetical protein YP_002037340.1 617469 D 512566 CDS YP_002037341.1 194396764 6479056 617839..619860 1 NC_011072.1 identified by match to protein family HMM PF07242; match to protein family HMM TIGR01654; hypothetical protein 619860 6479056 SPG_0626 Streptococcus pneumoniae G54 hypothetical protein YP_002037341.1 617839 D 512566 CDS YP_002037342.1 194397051 6480210 619862..620503 1 NC_011072.1 identified by match to protein family HMM PF00005; match to protein family HMM TIGR03608; ABC transporter ATP-binding protein 620503 6480210 SPG_0627 Streptococcus pneumoniae G54 ABC transporter ATP-binding protein YP_002037342.1 619862 D 512566 CDS YP_002037343.1 194397716 6479863 620607..621959 1 NC_011072.1 UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase 621959 murD 6479863 murD Streptococcus pneumoniae G54 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase YP_002037343.1 620607 D 512566 CDS YP_002037344.1 194398660 6480790 621963..623021 1 NC_011072.1 UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; involved in cell wall formation; inner membrane-associated; last step of peptidoglycan synthesis; undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase 623021 murG 6480790 murG Streptococcus pneumoniae G54 undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase YP_002037344.1 621963 D 512566 CDS YP_002037345.1 194396994 6479268 623031..624230 1 NC_011072.1 identified by match to protein family HMM PF03799; match to protein family HMM PF08478; cell division protein DivIB 624230 6479268 SPG_0630 Streptococcus pneumoniae G54 cell division protein DivIB YP_002037345.1 623031 D 512566 CDS YP_002037346.1 194398318 6480766 624463..625164 1 NC_011072.1 type 1 subfamily; involved in last step of pyrimidine biosynthesis; converts orotidine 5'-phosphate to UMP and carbon dioxide; OMP decarboxylase; OMPDCase; OMPdecase; orotidine 5'-phosphate decarboxylase 625164 pyrF 6480766 pyrF Streptococcus pneumoniae G54 orotidine 5'-phosphate decarboxylase YP_002037346.1 624463 D 512566 CDS YP_002037347.1 194396903 6479041 625198..625830 1 NC_011072.1 involved in fifth step of pyrimidine biosynthesis; converts orotidine 5'-phosphate and diphosphate to orotate and 5-phospho-alpha-D-ribose 1-diphosphate; orotate phosphoribosyltransferase 625830 pyrE 6479041 pyrE Streptococcus pneumoniae G54 orotate phosphoribosyltransferase YP_002037347.1 625198 D 512566 CDS YP_002037348.1 194397401 6480163 626063..626413 1 NC_011072.1 contains potential frameshift; hypothetical protein 626413 6480163 SPG_0633 Streptococcus pneumoniae G54 hypothetical protein YP_002037348.1 626063 D 512566 CDS YP_002037349.1 194397738 6480610 626509..627273 1 NC_011072.1 identified by glimmer; putative; hypothetical protein 627273 6480610 SPG_0634 Streptococcus pneumoniae G54 hypothetical protein YP_002037349.1 626509 D 512566 CDS YP_002037350.1 194397023 6480131 627273..628025 1 NC_011072.1 identified by glimmer; putative; hypothetical protein 628025 6480131 SPG_0635 Streptococcus pneumoniae G54 hypothetical protein YP_002037350.1 627273 D 512566 CDS YP_002037351.1 194397373 6479785 628029..628733 1 NC_011072.1 hypothetical protein 628733 6479785 SPG_0636 Streptococcus pneumoniae G54 hypothetical protein YP_002037351.1 628029 D 512566 CDS YP_002037352.1 194397992 6480536 628730..629377 1 NC_011072.1 identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 629377 6480536 SPG_0637 Streptococcus pneumoniae G54 ABC transporter ATP-binding protein YP_002037352.1 628730 D 512566 CDS YP_002037353.1 194398694 6478772 complement(629457..630005) 1 NC_011072.1 contains potential frameshift; ABC transporter substrate binding protein 630005 6478772 SPG_0638 Streptococcus pneumoniae G54 ABC transporter substrate binding protein YP_002037353.1 629457 R 512566 CDS YP_002037354.1 194397674 6479107 complement(630080..630193) 1 NC_011072.1 contains potential frameshift; ABC transporter substrate binding protein 630193 6479107 SPG_0639 Streptococcus pneumoniae G54 ABC transporter substrate binding protein YP_002037354.1 630080 R 512566 CDS YP_002037355.1 194398268 6479071 complement(630171..630323) 1 NC_011072.1 contains potential frameshift; ABC transporter substrate binding protein 630323 6479071 SPG_0640 Streptococcus pneumoniae G54 ABC transporter substrate binding protein YP_002037355.1 630171 R 512566 CDS YP_002037356.1 194396830 6478677 complement(630335..630730) 1 NC_011072.1 identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 630730 6478677 SPG_0641 Streptococcus pneumoniae G54 ABC transporter ATP-binding protein YP_002037356.1 630335 R 512566 CDS YP_002037357.1 194398396 6480025 complement(630830..631093) 1 NC_011072.1 ABC transporter ATP-binding protein 631093 6480025 SPG_0642 Streptococcus pneumoniae G54 ABC transporter ATP-binding protein YP_002037357.1 630830 R 512566 CDS YP_002037358.1 194398152 6478859 complement(631094..631381) 1 NC_011072.1 ABC transporter permease 631381 6478859 SPG_0643 Streptococcus pneumoniae G54 ABC transporter permease YP_002037358.1 631094 R 512566 CDS YP_002037359.1 194397462 6480332 complement(631391..631771) 1 NC_011072.1 identified by match to protein family HMM TIGR01726; ABC transporter permease 631771 6480332 SPG_0644 Streptococcus pneumoniae G54 ABC transporter permease YP_002037359.1 631391 R 512566 CDS YP_002037360.1 194398286 6480269 complement(631731..632411) 1 NC_011072.1 identified by match to protein family HMM PF00528; match to protein family HMM TIGR01726; ABC transporter permease 632411 6480269 SPG_0645 Streptococcus pneumoniae G54 ABC transporter permease YP_002037360.1 631731 R 512566 CDS YP_002037361.1 194398707 6479008 632626..632772 1 NC_011072.1 hypothetical protein 632772 6479008 SPG_0646 Streptococcus pneumoniae G54 hypothetical protein YP_002037361.1 632626 D 512566 CDS YP_002037362.1 194397421 6479058 632900..634390 1 NC_011072.1 class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1; lysyl-tRNA synthetase 634390 lysS 6479058 lysS Streptococcus pneumoniae G54 lysyl-tRNA synthetase YP_002037362.1 632900 D 512566 CDS YP_002037363.1 194396827 6479888 635014..636150 1 NC_011072.1 identified by match to protein family HMM PF01070; match to protein family HMM TIGR02708; L-lactate oxidase 636150 6479888 SPG_0648 Streptococcus pneumoniae G54 L-lactate oxidase YP_002037363.1 635014 D 512566 CDS YP_002037364.1 194397332 6479377 636707..637375 1 NC_011072.1 identified by match to protein family HMM PF03070; TENA/THI-4 family transcriptional regulator 637375 6479377 SPG_0649 Streptococcus pneumoniae G54 TENA/THI-4 family transcriptional regulator YP_002037364.1 636707 D 512566 CDS YP_002037365.1 194396734 6479907 637702..638484 1 NC_011072.1 catalyzes the formation of 4-methyl-5-(2-phosphoethyl)-thiazole and ADP from 4-methyl-5-(2-hydroxyethyl)-thiazole and ATP; hydroxyethylthiazole kinase 638484 thiM 6479907 thiM Streptococcus pneumoniae G54 hydroxyethylthiazole kinase YP_002037365.1 637702 D 512566 CDS YP_002037366.1 194398284 6479686 638486..639115 1 NC_011072.1 identified by match to protein family HMM PF02581; match to protein family HMM TIGR00693; thiamine-phosphate pyrophosphorylase 639115 thiE 6479686 thiE Streptococcus pneumoniae G54 thiamine-phosphate pyrophosphorylase YP_002037366.1 638486 D 512566 CDS YP_002037367.1 194397688 6479407 639674..640234 1 NC_011072.1 ABC transporter permease 640234 6479407 SPG_0652 Streptococcus pneumoniae G54 ABC transporter permease YP_002037367.1 639674 D 512566 CDS YP_002037368.1 194397083 6479255 640235..641620 1 NC_011072.1 identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 641620 6479255 SPG_0653 Streptococcus pneumoniae G54 ABC transporter ATP-binding protein YP_002037368.1 640235 D 512566 CDS YP_002037369.1 194397637 6480719 641622..642272 1 NC_011072.1 hypothetical protein 642272 6480719 SPG_0654 Streptococcus pneumoniae G54 hypothetical protein YP_002037369.1 641622 D 512566 CDS YP_002037370.1 194397130 6479145 642283..642975 1 NC_011072.1 identified by match to protein family HMM PF03070; transcriptional activator TenA 642975 6479145 SPG_0655 Streptococcus pneumoniae G54 transcriptional activator TenA YP_002037370.1 642283 D 512566 CDS YP_002037371.1 194398528 6480566 642980..643504 1 NC_011072.1 identified by match to protein family HMM TIGR02359; ThiW protein 643504 thiW 6480566 thiW Streptococcus pneumoniae G54 ThiW protein YP_002037371.1 642980 D 512566 CDS YP_002037372.1 194398082 6480663 643504..644307 1 NC_011072.1 identified by match to protein family HMM PF02110; hydroxyethylthiazole kinase 644307 6480663 SPG_0657 Streptococcus pneumoniae G54 hydroxyethylthiazole kinase YP_002037372.1 643504 D 512566 CDS YP_002037373.1 194398252 6479461 644300..644932 1 NC_011072.1 Condenses 4-methyl-5-(beta-hydroxyethyl)-thiazole monophosphate and 4-amino-5-hydroxymethyl pyrimidine pyrophosphate to form thiamine monophosphate; thiamine-phosphate pyrophosphorylase 644932 thiE 6479461 thiE Streptococcus pneumoniae G54 thiamine-phosphate pyrophosphorylase YP_002037373.1 644300 D 512566 CDS YP_002037374.1 194396707 6478646 complement(645141..645932) 1 NC_011072.1 catalyzes the formation of 4-amino-2-methyl-5-diphosphomethylpyrimidine; phosphomethylpyrimidine kinase 645932 thiD 6478646 thiD Streptococcus pneumoniae G54 phosphomethylpyrimidine kinase YP_002037374.1 645141 R 512566 CDS YP_002037375.1 194397351 6480310 646298..646693 1 NC_011072.1 identified by match to protein family HMM PF03965; match to protein family HMM TIGR02698; transcriptional regulator 646693 6480310 SPG_0660 Streptococcus pneumoniae G54 transcriptional regulator YP_002037375.1 646298 D 512566 CDS YP_002037376.1 194397816 6479756 646704..647075 1 NC_011072.1 hypothetical protein 647075 6479756 SPG_0661 Streptococcus pneumoniae G54 hypothetical protein YP_002037376.1 646704 D 512566 CDS YP_002037377.1 194398583 6480753 647085..649328 1 NC_011072.1 identified by match to protein family HMM PF00122; match to protein family HMM PF00702; match to protein family HMM PF08282; match to protein family HMM TIGR01494; match to protein family HMM TIGR01511; match to protein family HMM TIGR01525; E1-E2 family cation-transporting ATPase 649328 6480753 SPG_0662 Streptococcus pneumoniae G54 E1-E2 family cation-transporting ATPase YP_002037377.1 647085 D 512566 CDS YP_002037378.1 194397524 6479320 649535..651310 1 NC_011072.1 identified by match to protein family HMM PF00205; match to protein family HMM PF02775; match to protein family HMM PF02776; match to protein family HMM TIGR02720; pyruvate oxidase 651310 spxB 6479320 spxB Streptococcus pneumoniae G54 pyruvate oxidase YP_002037378.1 649535 D 512566 CDS YP_002037379.1 194397616 6479536 651421..651768 1 NC_011072.1 identified by match to protein family HMM PF00903; hypothetical protein 651768 6479536 SPG_0664 Streptococcus pneumoniae G54 hypothetical protein YP_002037379.1 651421 D 512566 CDS YP_002037380.1 194398057 6478831 complement(651980..652393) 1 NC_011072.1 IS630-SpnII transposase 652393 6478831 SPG_0665 Streptococcus pneumoniae G54 IS630-SpnII transposase YP_002037380.1 651980 R 512566 CDS YP_002037381.1 194397741 6478691 complement(652425..652691) 1 NC_011072.1 IS630-SpnII transposase 652691 6478691 SPG_0666 Streptococcus pneumoniae G54 IS630-SpnII transposase YP_002037381.1 652425 R 512566 CDS YP_002037382.1 194397139 6480384 653206..653490 1 NC_011072.1 contains potential frameshift; identified by glimmer; putative; hypothetical protein 653490 6480384 SPG_0667 Streptococcus pneumoniae G54 hypothetical protein YP_002037382.1 653206 D 512566 CDS YP_002037383.1 194397377 6480018 653622..654566 1 NC_011072.1 identified by match to protein family HMM PF01238; match to protein family HMM TIGR00218; mannose-6-phosphate isomerase 654566 6480018 SPG_0668 Streptococcus pneumoniae G54 mannose-6-phosphate isomerase YP_002037383.1 653622 D 512566 CDS YP_002037384.1 194397961 6479806 complement(654587..656065) 1 NC_011072.1 identified by match to protein family HMM PF00209; sodium-dependent transporter 656065 6479806 SPG_0669 Streptococcus pneumoniae G54 sodium-dependent transporter YP_002037384.1 654587 R 512566 CDS YP_002037385.1 194396655 6478914 656170..656919 1 NC_011072.1 identified by match to protein family HMM PF00376; match to protein family HMM PF07739; match to protein family HMM PF09278; MerR family transcriptional regulator 656919 6478914 SPG_0670 Streptococcus pneumoniae G54 MerR family transcriptional regulator YP_002037385.1 656170 D 512566 CDS YP_002037386.1 194397382 6480081 complement(656939..657394) 1 NC_011072.1 identified by match to protein family HMM PF00293; MutT/nudix family protein 657394 6480081 SPG_0671 Streptococcus pneumoniae G54 MutT/nudix family protein YP_002037386.1 656939 R 512566 CDS YP_002037387.1 194398231 6480420 complement(657414..658589) 1 NC_011072.1 identified by match to protein family HMM PF03486; match to protein family HMM TIGR00275; hypothetical protein 658589 6480420 SPG_0672 Streptococcus pneumoniae G54 hypothetical protein YP_002037387.1 657414 R 512566 CDS YP_002037388.1 194398345 6479142 complement(658648..659493) 1 NC_011072.1 identified by match to protein family HMM PF02645; match to protein family HMM TIGR00762; hypothetical protein 659493 6479142 SPG_0673 Streptococcus pneumoniae G54 hypothetical protein YP_002037388.1 658648 R 512566 CDS YP_002037389.1 194397507 6480259 659618..660175 1 NC_011072.1 identified by match to protein family HMM PF00440; TetR family transcriptional regulator 660175 6480259 SPG_0674 Streptococcus pneumoniae G54 TetR family transcriptional regulator YP_002037389.1 659618 D 512566 CDS YP_002037390.1 194398250 6479422 660194..660661 1 NC_011072.1 identified by match to protein family HMM PF00383; cytidine and deoxycytidylate deaminase family protein 660661 6479422 SPG_0675 Streptococcus pneumoniae G54 cytidine and deoxycytidylate deaminase family protein YP_002037390.1 660194 D 512566 CDS YP_002037391.1 194397960 6478644 660729..661379 1 NC_011072.1 Catalyzes the formation of uracil and 5-phospho-alpha-D-ribosy 1-diphosphate from UMP and diphosphate; uracil phosphoribosyltransferase 661379 upp 6478644 upp Streptococcus pneumoniae G54 uracil phosphoribosyltransferase YP_002037391.1 660729 D 512566 CDS YP_002037392.1 194398443 6478913 661553..661996 1 NC_011072.1 contains potential frameshift; identified by match to protein family HMM PF00574; ATP-dependent Clp protease proteolytic subunit 661996 6478913 SPG_0677 Streptococcus pneumoniae G54 ATP-dependent Clp protease proteolytic subunit YP_002037392.1 661553 D 512566 CDS YP_002037393.1 194397675 6480552 662013..662144 1 NC_011072.1 contains potential frameshift; ATP-dependent Clp protease proteolytic subunit 662144 6480552 SPG_0678 Streptococcus pneumoniae G54 ATP-dependent Clp protease proteolytic subunit YP_002037393.1 662013 D 512566 CDS YP_002037394.1 194397053 6479072 662223..662471 1 NC_011072.1 identified by glimmer; putative; hypothetical protein 662471 6479072 SPG_0679 Streptococcus pneumoniae G54 hypothetical protein YP_002037394.1 662223 D 512566 CDS YP_002037395.1 194398588 6479844 662572..663732 1 NC_011072.1 identified by match to protein family HMM PF01094; branched-chain amino acid ABC transporter periplasmic protein 663732 livJ 6479844 livJ Streptococcus pneumoniae G54 branched-chain amino acid ABC transporter periplasmic protein YP_002037395.1 662572 D 512566 CDS YP_002037396.1 194397862 6478820 664000..664869 1 NC_011072.1 identified by match to protein family HMM PF02653; branched-chain amino acid ABC transporter permease 664869 livH 6478820 livH Streptococcus pneumoniae G54 branched-chain amino acid ABC transporter permease YP_002037396.1 664000 D 512566 CDS YP_002037397.1 194397412 6480749 664873..665829 1 NC_011072.1 identified by match to protein family HMM PF02653; branched-chain amino acid ABC transporter permease 665829 livM 6480749 livM Streptococcus pneumoniae G54 branched-chain amino acid ABC transporter permease YP_002037397.1 664873 D 512566 CDS YP_002037398.1 194396659 6480391 665829..666593 1 NC_011072.1 identified by match to protein family HMM PF00005; branched-chain amino acid ABC transporter ATP-binding protein 666593 livG 6480391 livG Streptococcus pneumoniae G54 branched-chain amino acid ABC transporter ATP-binding protein YP_002037398.1 665829 D 512566 CDS YP_002037399.1 194397848 6479765 666593..667303 1 NC_011072.1 identified by match to protein family HMM PF00005; branched-chain amino acid ABC transporter ATP-binding protein 667303 livF 6479765 livF Streptococcus pneumoniae G54 branched-chain amino acid ABC transporter ATP-binding protein YP_002037399.1 666593 D 512566 CDS YP_002037400.1 194398244 6480443 667611..668267 1 NC_011072.1 identified by match to protein family HMM PF00571; acetoin utilization protein AcuB 668267 6480443 SPG_0685 Streptococcus pneumoniae G54 acetoin utilization protein AcuB YP_002037400.1 667611 D 512566 CDS YP_002037401.1 194397508 6479498 668481..669470 1 NC_011072.1 recognizes the termination signals UGA and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF2; in some organisms control of PrfB protein levels is maintained through a +1 ribosomal frameshifting mechanism; this protein is similar to release factor 1; peptide chain release factor 2 669470 prfB 6479498 prfB Streptococcus pneumoniae G54 peptide chain release factor 2 YP_002037401.1 668481 D 512566 CDS YP_002037402.1 194397011 6479423 669488..670180 1 NC_011072.1 identified by match to protein family HMM PF00005; match to protein family HMM TIGR02673; cell division ATP-binding protein FtsE 670180 ftsE 6479423 ftsE Streptococcus pneumoniae G54 cell division ATP-binding protein FtsE YP_002037402.1 669488 D 512566 CDS YP_002037403.1 194397096 6479644 670173..671099 1 NC_011072.1 identified by match to protein family HMM PF02687; Cell division protein FtsX 671099 6479644 SPG_0688 Streptococcus pneumoniae G54 Cell division protein FtsX YP_002037403.1 670173 D 512566 CDS YP_002037404.1 194398642 6479948 671385..671897 1 NC_011072.1 contains potential frameshift; PTS system transporter subunit IIBCA 671897 6479948 SPG_0689 Streptococcus pneumoniae G54 PTS system transporter subunit IIBCA YP_002037404.1 671385 D 512566 CDS YP_002037405.1 194398579 6479079 672079..673566 1 NC_011072.1 contains potential frameshift; identified by match to protein family HMM PF00358; match to protein family HMM PF00367; match to protein family HMM TIGR00826; match to protein family HMM TIGR00830; PTS system transporter subunit IIBCA 673566 6479079 SPG_0690 Streptococcus pneumoniae G54 PTS system transporter subunit IIBCA YP_002037405.1 672079 D 512566 CDS YP_002037406.1 194398123 6479185 673618..673950 1 NC_011072.1 contains potential frameshift; identified by glimmer; putative; hypothetical protein 673950 6479185 SPG_0691 Streptococcus pneumoniae G54 hypothetical protein YP_002037406.1 673618 D 512566 CDS YP_002037407.1 194396800 6480393 673964..674434 1 NC_011072.1 contains potential frameshift; hypothetical protein 674434 6480393 SPG_0692 Streptococcus pneumoniae G54 hypothetical protein YP_002037407.1 673964 D 512566 CDS YP_002037408.1 194398476 6479405 674574..675917 1 NC_011072.1 identified by match to protein family HMM PF00270; match to protein family HMM PF00271; ATP-dependent RNA helicase 675917 6479405 SPG_0693 Streptococcus pneumoniae G54 ATP-dependent RNA helicase YP_002037408.1 674574 D 512566 CDS YP_002037409.1 194397216 6480305 676294..677484 1 NC_011072.1 catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase; S-adenosylmethionine synthetase 677484 metK 6480305 metK Streptococcus pneumoniae G54 S-adenosylmethionine synthetase YP_002037409.1 676294 D 512566 CDS YP_002037410.1 194397157 6480573 678037..678972 1 NC_011072.1 catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway; subclass 1A is a dimer formed by two identical PyrD subunits each containing an FMN group; dihydroorotate dehydrogenase 1A 678972 6480573 SPG_0695 Streptococcus pneumoniae G54 dihydroorotate dehydrogenase 1A YP_002037410.1 678037 D 512566 CDS YP_002037411.1 194398594 6479350 679006..680043 1 NC_011072.1 required for the assembly and function of the DNAX complex which is required for the assembly of the beta subunit onto primed DNA; DNA polymerase III subunit delta 680043 holA 6479350 holA Streptococcus pneumoniae G54 DNA polymerase III subunit delta YP_002037411.1 679006 D 512566 CDS YP_002037412.1 194397985 6478940 680216..680821 1 NC_011072.1 identified by match to protein family HMM PF00081; match to protein family HMM PF02777; manganese-dependent superoxide dismutase 680821 sodA 6478940 sodA Streptococcus pneumoniae G54 manganese-dependent superoxide dismutase YP_002037412.1 680216 D 512566 CDS YP_002037413.1 194398550 6478643 680978..681508 1 NC_011072.1 identified by glimmer; putative; hypothetical protein 681508 6478643 SPG_0698 Streptococcus pneumoniae G54 hypothetical protein YP_002037413.1 680978 D 512566 CDS YP_002037414.1 194397178 6479892 681529..682614 1 NC_011072.1 23S rRNA m2A2503 methyltransferase; methylates the C2 position of the A2530 nucleotide in 23S rRNA; may be involved in antibiotic resistance; ribosomal RNA large subunit methyltransferase N 682614 6479892 SPG_0699 Streptococcus pneumoniae G54 ribosomal RNA large subunit methyltransferase N YP_002037414.1 681529 D 512566 CDS YP_002037415.1 194397620 6479099 682713..683096 1 NC_011072.1 identified by match to protein family HMM PF04892; hypothetical protein 683096 6479099 SPG_0700 Streptococcus pneumoniae G54 hypothetical protein YP_002037415.1 682713 D 512566 CDS YP_002037416.1 194397780 6479415 683098..684639 1 NC_011072.1 identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 684639 6479415 SPG_0701 Streptococcus pneumoniae G54 ABC transporter ATP-binding protein YP_002037416.1 683098 D 512566 CDS YP_002037417.1 194398488 6479698 complement(684696..685499) 1 NC_011072.1 identified by match to protein family HMM PF00160; peptidyl-prolyl cis-trans isomerase, cyclophilin-type 685499 6479698 SPG_0702 Streptococcus pneumoniae G54 peptidyl-prolyl cis-trans isomerase, cyclophilin-type YP_002037417.1 684696 R 512566 CDS YP_002037418.1 194396867 6479974 complement(685613..685804) 1 NC_011072.1 hypothetical protein 685804 6479974 SPG_0703 Streptococcus pneumoniae G54 hypothetical protein YP_002037418.1 685613 R 512566 CDS YP_002037419.1 194397009 6478725 complement(686283..686483) 1 NC_011072.1 hypothetical protein 686483 6478725 SPG_0704 Streptococcus pneumoniae G54 hypothetical protein YP_002037419.1 686283 R 512566 CDS YP_002037420.1 194398586 6480247 686662..686934 1 NC_011072.1 binds to lower part of 30S body where it stabilizes two domains; required for efficient assembly of 30S; in Escherichia coli this protein has nuclease activity; 30S ribosomal protein S16 686934 rpsP 6480247 rpsP Streptococcus pneumoniae G54 30S ribosomal protein S16 YP_002037420.1 686662 D 512566 CDS YP_002037421.1 194398226 6478818 686954..687193 1 NC_011072.1 hypothetical protein 687193 6478818 SPG_0706 Streptococcus pneumoniae G54 hypothetical protein YP_002037421.1 686954 D 512566 CDS YP_002037422.1 194398676 6478768 687770..688558 1 NC_011072.1 identified by match to protein family HMM PF00561; hypothetical protein 688558 6478768 SPG_0707 Streptococcus pneumoniae G54 hypothetical protein YP_002037422.1 687770 D 512566 CDS YP_002037423.1 194397767 6479299 688589..689107 1 NC_011072.1 Essential for efficient processing of 16S rRNA; 16S rRNA-processing protein RimM 689107 rimM 6479299 rimM Streptococcus pneumoniae G54 16S rRNA-processing protein RimM YP_002037423.1 688589 D 512566 CDS YP_002037424.1 194397425 6480218 689097..689816 1 NC_011072.1 methylates guanosine-37 in various tRNAs; uses S-adenosyl-L-methionine to transfer methyl group to tRNA; tRNA (guanine-N(1)-)-methyltransferase 689816 trmD 6480218 trmD Streptococcus pneumoniae G54 tRNA (guanine-N(1)-)-methyltransferase YP_002037424.1 689097 D 512566 CDS YP_002037425.1 194397979 6480185 689828..690166 1 NC_011072.1 identified by glimmer; putative; hypothetical protein 690166 6480185 SPG_0710 Streptococcus pneumoniae G54 hypothetical protein YP_002037425.1 689828 D 512566 CDS YP_002037426.1 194397258 6479062 complement(690196..690516) 1 NC_011072.1 identified by glimmer; putative; hypothetical protein 690516 6479062 SPG_0711 Streptococcus pneumoniae G54 hypothetical protein YP_002037426.1 690196 R 512566 CDS YP_002037427.1 194398190 6479224 690614..690829 1 NC_011072.1 hypothetical protein 690829 6479224 SPG_0712 Streptococcus pneumoniae G54 hypothetical protein YP_002037427.1 690614 D 512566 CDS YP_002037428.1 194397464 6480779 complement(691034..691570) 1 NC_011072.1 identified by match to protein family HMM PF02632; biotin synthase 691570 bioY 6480779 bioY Streptococcus pneumoniae G54 biotin synthase YP_002037428.1 691034 R 512566 CDS YP_002037429.1 194396977 6479997 complement(691766..693112) 1 NC_011072.1 catalyzes the reduction of 2 glutathione to glutathione disulfide; maintains high levels of reduced glutathione in the cytosol; involved in redox regulation and oxidative defense; glutathione reductase 693112 gor 6479997 gor Streptococcus pneumoniae G54 glutathione reductase YP_002037429.1 691766 R 512566 CDS YP_002037430.1 194398457 6479953 693398..694597 1 NC_011072.1 identified by match to protein family HMM TIGR01730; RND family efflux transporter 694597 6479953 SPG_0715 Streptococcus pneumoniae G54 RND family efflux transporter YP_002037430.1 693398 D 512566 CDS YP_002037431.1 194397887 6480738 694581..695282 1 NC_011072.1 identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 695282 6480738 SPG_0716 Streptococcus pneumoniae G54 ABC transporter ATP-binding protein YP_002037431.1 694581 D 512566 CDS YP_002037432.1 194396728 6480815 695284..696543 1 NC_011072.1 identified by match to protein family HMM PF02687; ABC transporter permease 696543 6480815 SPG_0717 Streptococcus pneumoniae G54 ABC transporter permease YP_002037432.1 695284 D 512566 CDS YP_002037433.1 194397413 6479856 696667..698664 1 NC_011072.1 methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content; methionyl-tRNA synthetase 698664 metG 6479856 metG Streptococcus pneumoniae G54 methionyl-tRNA synthetase YP_002037433.1 696667 D 512566 CDS YP_002037434.1 194398326 6480392 699085..699405 1 NC_011072.1 identified by match to protein family HMM PF03551; PadR family transcriptional regulator 699405 6480392 SPG_0719 Streptococcus pneumoniae G54 PadR family transcriptional regulator YP_002037434.1 699085 D 512566 CDS YP_002037435.1 194398467 6479494 699409..700224 1 NC_011072.1 hypothetical protein 700224 6479494 SPG_0720 Streptococcus pneumoniae G54 hypothetical protein YP_002037435.1 699409 D 512566 CDS YP_002037436.1 194397870 6480787 700299..701225 1 NC_011072.1 identified by match to protein family HMM PF00248; aldo/keto reductase family oxidoreductase 701225 6480787 SPG_0721 Streptococcus pneumoniae G54 aldo/keto reductase family oxidoreductase YP_002037436.1 700299 D 512566 CDS YP_002037437.1 194397561 6480255 701321..701557 1 NC_011072.1 hypothetical protein 701557 6480255 SPG_0722 Streptococcus pneumoniae G54 hypothetical protein YP_002037437.1 701321 D 512566 CDS YP_002037438.1 194396955 6479313 701550..702248 1 NC_011072.1 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis; 3-ketoacyl-(acyl-carrier-protein) reductase 702248 fabG 6479313 fabG Streptococcus pneumoniae G54 3-ketoacyl-(acyl-carrier-protein) reductase YP_002037438.1 701550 D 512566 CDS YP_002037439.1 194397108 6479859 702259..702759 1 NC_011072.1 identified by match to protein family HMM PF00293; MutT/nudix family protein 702759 6479859 SPG_0724 Streptococcus pneumoniae G54 MutT/nudix family protein YP_002037439.1 702259 D 512566 CDS YP_002037440.1 194398592 6479950 702737..703606 1 NC_011072.1 identified by match to protein family HMM PF02896; hypothetical protein 703606 6479950 SPG_0725 Streptococcus pneumoniae G54 hypothetical protein YP_002037440.1 702737 D 512566 CDS YP_002037441.1 194396804 6478938 703581..704021 1 NC_011072.1 identified by match to protein family HMM PF06171; hypothetical protein 704021 6478938 SPG_0726 Streptococcus pneumoniae G54 hypothetical protein YP_002037441.1 703581 D 512566 CDS YP_002037442.1 194398336 6479565 704144..706690 1 NC_011072.1 identified by match to protein family HMM PF01433; aminopeptidase N 706690 6479565 SPG_0727 Streptococcus pneumoniae G54 aminopeptidase N YP_002037442.1 704144 D 512566 CDS YP_002037443.1 194398608 6479630 706799..707473 1 NC_011072.1 Guenzi Mol Microbiol. 1994 12(3):505-15.; identified by match to protein family HMM PF00072; match to protein family HMM PF00486; CiaR response regulator TCS05 707473 ciaR 6479630 ciaR Streptococcus pneumoniae G54 CiaR response regulator TCS05 YP_002037443.1 706799 D 512566 CDS YP_002037444.1 194398000 6479194 707463..708797 1 NC_011072.1 Guenzi Mol Microbiol. 1994 12(3):505-15.; identified by match to protein family HMM PF00512; match to protein family HMM PF02518; CiaH histidine kinase TCS05 708797 ciaH 6479194 ciaH Streptococcus pneumoniae G54 CiaH histidine kinase TCS05 YP_002037444.1 707463 D 512566 CDS YP_002037445.1 194396833 6479226 complement(708831..709118) 1 NC_011072.1 hypothetical protein 709118 6479226 SPG_0730 Streptococcus pneumoniae G54 hypothetical protein YP_002037445.1 708831 R 512566 CDS YP_002037446.1 194398653 6480410 709258..710187 1 NC_011072.1 identified by glimmer; putative; hypothetical protein 710187 6480410 SPG_0731 Streptococcus pneumoniae G54 hypothetical protein YP_002037446.1 709258 D 512566 CDS YP_002037447.1 194397188 6478887 710387..712837 1 NC_011072.1 unwinds DNA; bifunctional ATP-dependent DNA helicase/DNA polymerase III subunit epsilon 712837 6478887 SPG_0732 Streptococcus pneumoniae G54 bifunctional ATP-dependent DNA helicase/DNA polymerase III subunit epsilon YP_002037447.1 710387 D 512566 CDS YP_002037448.1 194396763 6478733 712874..714097 1 NC_011072.1 identified by match to protein family HMM PF01098; FtsW/RodA/SpoVE family cell cycle protein 714097 6478733 SPG_0733 Streptococcus pneumoniae G54 FtsW/RodA/SpoVE family cell cycle protein YP_002037448.1 712874 D 512566 CDS YP_002037449.1 194398431 6480180 714108..714662 1 NC_011072.1 identified by match to protein family HMM PF01965; match to protein family HMM TIGR01383; 4-methyl-5(b-hydroxyethyl)-thiazole monophosphate biosynthesis protein 714662 6480180 SPG_0734 Streptococcus pneumoniae G54 4-methyl-5(b-hydroxyethyl)-thiazole monophosphate biosynthesis protein YP_002037449.1 714108 D 512566 CDS YP_002037450.1 194397948 6480381 714747..715310 1 NC_011072.1 identified by match to protein family HMM PF00702; match to protein family HMM TIGR01549; haloacid dehalogenase-like hydrolase 715310 6480381 SPG_0735 Streptococcus pneumoniae G54 haloacid dehalogenase-like hydrolase YP_002037450.1 714747 D 512566 CDS YP_002037451.1 194396954 6479188 715325..717271 1 NC_011072.1 negatively supercoils closed circular double-stranded DNA; DNA gyrase subunit B 717271 gyrB 6479188 gyrB Streptococcus pneumoniae G54 DNA gyrase subunit B YP_002037451.1 715325 D 512566 CDS YP_002037452.1 194398667 6479754 717353..719080 1 NC_011072.1 acts to negatively regulates ftsZ ring formation by modulating the frequency and position of the ftsZ ring formation; septation ring formation regulator EzrA 719080 ezrA 6479754 ezrA Streptococcus pneumoniae G54 septation ring formation regulator EzrA YP_002037452.1 717353 D 512566 CDS YP_002037453.1 194397267 6479029 complement(719810..720133) 1 NC_011072.1 identified by match to protein family HMM PF05717; IS66-Spn1 transposase 720133 6479029 SPG_0738 Streptococcus pneumoniae G54 IS66-Spn1 transposase YP_002037453.1 719810 R 512566 CDS YP_002037454.1 194397207 6479586 complement(720394..720693) 1 NC_011072.1 identified by match to protein family HMM PF08860; hypothetical protein 720693 6479586 SPG_0739 Streptococcus pneumoniae G54 hypothetical protein YP_002037454.1 720394 R 512566 CDS YP_002037455.1 194398294 6480041 complement(720858..721121) 1 NC_011072.1 contains potential frameshift; hypothetical protein 721121 6480041 SPG_0740 Streptococcus pneumoniae G54 hypothetical protein YP_002037455.1 720858 R 512566 CDS YP_002037456.1 194397803 6478975 721391..721741 1 NC_011072.1 identified by match to protein family HMM PF01710; IS630-Spn1 transposase 721741 6478975 SPG_0741 Streptococcus pneumoniae G54 IS630-Spn1 transposase YP_002037456.1 721391 D 512566 CDS YP_002037457.1 194398158 6480372 721900..722040 1 NC_011072.1 IS630-Spn1 transposase 722040 6480372 SPG_0742 Streptococcus pneumoniae G54 IS630-Spn1 transposase YP_002037457.1 721900 D 512566 CDS YP_002037458.1 194397701 6480594 complement(722550..724808) 1 NC_011072.1 identified by match to protein family HMM PF00004; match to protein family HMM PF02151; match to protein family HMM PF07724; match to protein family HMM PF07728; ATP-dependent Clp protease ATP-binding subunit ClpE 724808 6480594 SPG_0743 Streptococcus pneumoniae G54 ATP-dependent Clp protease ATP-binding subunit ClpE YP_002037458.1 722550 R 512566 CDS YP_002037459.1 194397576 6479131 complement(725037..725267) 1 NC_011072.1 identified by match to protein family HMM PF08796; hypothetical protein 725267 6479131 SPG_0744 Streptococcus pneumoniae G54 hypothetical protein YP_002037459.1 725037 R 512566 CDS YP_002037460.1 194396808 6478822 725457..726140 1 NC_011072.1 identified by match to protein family HMM PF00528; match to protein family HMM TIGR01726; amino acid ABC transporter permease 726140 6478822 SPG_0745 Streptococcus pneumoniae G54 amino acid ABC transporter permease YP_002037460.1 725457 D 512566 CDS YP_002037461.1 194398506 6479427 726140..726874 1 NC_011072.1 identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 726874 6479427 SPG_0746 Streptococcus pneumoniae G54 ABC transporter ATP-binding protein YP_002037461.1 726140 D 512566 CDS YP_002037462.1 194397920 6480721 727007..727885 1 NC_011072.1 catalyzes the formation of 5,10-methenyltetrahydrofolate from 5,10-methylenetetrahydrofolate and subsequent formation of 10-formyltetrahydrofolate from 5,10-methenyltetrahydrofolate; bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase 727885 6480721 SPG_0747 Streptococcus pneumoniae G54 bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase YP_002037462.1 727007 D 512566 CDS YP_002037463.1 194397971 6479026 728027..728899 1 NC_011072.1 identified by match to protein family HMM PF01256; match to protein family HMM TIGR00196; YjeF-like protein 728899 6479026 SPG_0748 Streptococcus pneumoniae G54 YjeF-like protein YP_002037463.1 728027 D 512566 CDS YP_002037464.1 194397227 6478730 729181..729864 1 NC_011072.1 Catalyzes D-ribose 5-phosphate --> D-ribulose 5-phosphate in the nonoxidative branch of the pentose phosphate pathway; ribose-5-phosphate isomerase A 729864 ripA 6478730 ripA Streptococcus pneumoniae G54 ribose-5-phosphate isomerase A YP_002037464.1 729181 D 512566 CDS YP_002037465.1 194397073 6480030 729878..731089 1 NC_011072.1 catalyzes the transfer of phosphate between the C1 and C5 carbons of pentose; phosphopentomutase 731089 6480030 SPG_0750 Streptococcus pneumoniae G54 phosphopentomutase YP_002037465.1 729878 D 512566 CDS YP_002037466.1 194398364 6479766 731091..731633 1 NC_011072.1 identified by match to protein family HMM PF08002; hypothetical protein 731633 6479766 SPG_0751 Streptococcus pneumoniae G54 hypothetical protein YP_002037466.1 731091 D 512566 CDS YP_002037467.1 194397678 6480067 731649..732458 1 NC_011072.1 catalyzes the formation of a purine and ribose phosphate from a purine nucleoside; in E. coli this enzyme functions in xanthosine degradation; purine nucleoside phosphorylase 732458 pnp 6480067 pnp Streptococcus pneumoniae G54 purine nucleoside phosphorylase YP_002037467.1 731649 D 512566 CDS YP_002037468.1 194397082 6478838 732934..733329 1 NC_011072.1 hypothetical protein 733329 6478838 SPG_0753 Streptococcus pneumoniae G54 hypothetical protein YP_002037468.1 732934 D 512566 CDS YP_002037469.1 194398625 6480311 733339..733914 1 NC_011072.1 hypothetical protein 733914 6480311 SPG_0754 Streptococcus pneumoniae G54 hypothetical protein YP_002037469.1 733339 D 512566 CDS YP_002037470.1 194398018 6478680 733939..734451 1 NC_011072.1 hypothetical protein 734451 6478680 SPG_0755 Streptococcus pneumoniae G54 hypothetical protein YP_002037470.1 733939 D 512566 CDS YP_002037471.1 194396826 6478788 735105..735815 1 NC_011072.1 catalyzes the reversible phosphorolysis of ribonucleosides and 2'- deoxyribonucleosides to the free base and (2'-deoxy)ribose-1- phosphate; purine nucleoside phosphorylase 735815 deoD 6478788 deoD Streptococcus pneumoniae G54 purine nucleoside phosphorylase YP_002037471.1 735105 D 512566 CDS YP_002037472.1 194397404 6478666 complement(735838..736362) 1 NC_011072.1 topology modulation protein 736362 6478666 SPG_0757 Streptococcus pneumoniae G54 topology modulation protein YP_002037472.1 735838 R 512566 CDS YP_002037473.1 194397721 6480155 complement(736415..736651) 1 NC_011072.1 binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase; 30S ribosomal protein S20 736651 rpsT 6480155 rpsT Streptococcus pneumoniae G54 30S ribosomal protein S20 YP_002037473.1 736415 R 512566 CDS YP_002037474.1 194398335 6480197 complement(736719..737639) 1 NC_011072.1 catalyzes the formation of (R)-4'-phosphopantothenate in coenzyme A biosynthesis; pantothenate kinase 737639 coaA 6480197 coaA Streptococcus pneumoniae G54 pantothenate kinase YP_002037474.1 736719 R 512566 CDS YP_002037475.1 194397997 6479629 737829..738065 1 NC_011072.1 hypothetical protein 738065 6479629 SPG_0760 Streptococcus pneumoniae G54 hypothetical protein YP_002037475.1 737829 D 512566 CDS YP_002037476.1 194398552 6479614 738439..739029 1 NC_011072.1 identified by match to protein family HMM PF05175; methyltransferase small domain 739029 6479614 SPG_0761 Streptococcus pneumoniae G54 methyltransferase small domain YP_002037476.1 738439 D 512566 CDS YP_002037477.1 194396818 6479894 739026..740303 1 NC_011072.1 Catalyzes the reversible phosphorolysis of pyrimidines in the nucleotide synthesis salvage pathway; pyrimidine-nucleoside phosphorylase 740303 pdp 6479894 pdp Streptococcus pneumoniae G54 pyrimidine-nucleoside phosphorylase YP_002037477.1 739026 D 512566 CDS YP_002037478.1 194397321 6478793 740321..740983 1 NC_011072.1 catalyzes the formation of D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-D-ribose-5-phosphate; deoxyribose-phosphate aldolase 740983 deoC 6478793 deoC Streptococcus pneumoniae G54 deoxyribose-phosphate aldolase YP_002037478.1 740321 D 512566 CDS YP_002037479.1 194398262 6480462 740970..741359 1 NC_011072.1 Reclaims exogenous and endogenous cytidine and 2'-deoxycytidine molecules for UMP synthesis; cytidine deaminase 741359 6480462 SPG_0764 Streptococcus pneumoniae G54 cytidine deaminase YP_002037479.1 740970 D 512566 CDS YP_002037480.1 194396814 6479418 741450..742502 1 NC_011072.1 identified by match to protein family HMM PF02608; membrane protein 742502 6479418 SPG_0765 Streptococcus pneumoniae G54 membrane protein YP_002037480.1 741450 D 512566 CDS YP_002037481.1 194398108 6479417 742646..744181 1 NC_011072.1 identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 744181 6479417 SPG_0766 Streptococcus pneumoniae G54 ABC transporter ATP-binding protein YP_002037481.1 742646 D 512566 CDS YP_002037482.1 194396866 6480619 744174..745232 1 NC_011072.1 identified by match to protein family HMM PF02653; ABC transporter permease 745232 6480619 SPG_0767 Streptococcus pneumoniae G54 ABC transporter permease YP_002037482.1 744174 D 512566 CDS YP_002037483.1 194397165 6479557 745235..746191 1 NC_011072.1 identified by match to protein family HMM PF02653; ABC transporter permease 746191 6479557 SPG_0768 Streptococcus pneumoniae G54 ABC transporter permease YP_002037483.1 745235 D 512566 CDS YP_002037484.1 194397644 6479353 746275..746487 1 NC_011072.1 IS3-Spn1 transposase 746487 6479353 SPG_0769 Streptococcus pneumoniae G54 IS3-Spn1 transposase YP_002037484.1 746275 D 512566 CDS YP_002037485.1 194397802 6479229 746624..746791 1 NC_011072.1 IS3-Spn1 transposase 746791 6479229 SPG_0770 Streptococcus pneumoniae G54 IS3-Spn1 transposase YP_002037485.1 746624 D 512566 CDS YP_002037486.1 194398274 6480371 746791..747525 1 NC_011072.1 identified by match to protein family HMM PF00665; IS3-Spn1 transposase 747525 6480371 SPG_0771 Streptococcus pneumoniae G54 IS3-Spn1 transposase YP_002037486.1 746791 D 512566 CDS YP_002037487.1 194397837 6478656 complement(747657..748298) 1 NC_011072.1 involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsX; putative glycerol-3-phosphate acyltransferase PlsY 748298 6478656 SPG_0772 Streptococcus pneumoniae G54 putative glycerol-3-phosphate acyltransferase PlsY YP_002037487.1 747657 R 512566 CDS YP_002037488.1 194398307 6480455 748434..750377 1 NC_011072.1 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling; DNA topoisomerase IV subunit B 750377 parE 6480455 parE Streptococcus pneumoniae G54 DNA topoisomerase IV subunit B YP_002037488.1 748434 D 512566 CDS YP_002037489.1 194396882 6479164 750498..750623 1 NC_011072.1 hypothetical protein 750623 6479164 SPG_0774 Streptococcus pneumoniae G54 hypothetical protein YP_002037489.1 750498 D 512566 CDS YP_002037490.1 194397352 6479292 750797..753268 1 NC_011072.1 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling; DNA topoisomerase IV subunit A 753268 parC 6479292 parC Streptococcus pneumoniae G54 DNA topoisomerase IV subunit A YP_002037490.1 750797 D 512566 CDS YP_002037491.1 194396820 6479757 753378..754400 1 NC_011072.1 catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids; branched-chain amino acid aminotransferase 754400 6479757 SPG_0776 Streptococcus pneumoniae G54 branched-chain amino acid aminotransferase YP_002037491.1 753378 D 512566 CDS YP_002037492.1 194398356 6479343 754456..755160 1 NC_011072.1 identified by glimmer; putative; hypothetical protein 755160 6479343 SPG_0777 Streptococcus pneumoniae G54 hypothetical protein YP_002037492.1 754456 D 512566 CDS YP_002037493.1 194397756 6479971 755225..755914 1 NC_011072.1 identified by glimmer; putative; hypothetical protein 755914 6479971 SPG_0778 Streptococcus pneumoniae G54 hypothetical protein YP_002037493.1 755225 D 512566 CDS YP_002037494.1 194397710 6479868 755911..756834 1 NC_011072.1 identified by glimmer; putative; hypothetical protein 756834 6479868 SPG_0779 Streptococcus pneumoniae G54 hypothetical protein YP_002037494.1 755911 D 512566 CDS YP_002037495.1 194397078 6480655 756849..757493 1 NC_011072.1 catalyzes the removal of 5-oxoproline from various penultimate amino acid residues except L-proline; pyrrolidone-carboxylate peptidase 757493 6480655 SPG_0780 Streptococcus pneumoniae G54 pyrrolidone-carboxylate peptidase YP_002037495.1 756849 D 512566 CDS YP_002037496.1 194398626 6479657 757661..757891 1 NC_011072.1 hypothetical protein 757891 6479657 SPG_0781 Streptococcus pneumoniae G54 hypothetical protein YP_002037496.1 757661 D 512566 CDS YP_002037497.1 194397407 6480373 758264..759466 1 NC_011072.1 in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins; 30S ribosomal protein S1 759466 rpsA 6480373 rpsA Streptococcus pneumoniae G54 30S ribosomal protein S1 YP_002037497.1 758264 D 512566 CDS YP_002037498.1 194396839 6480062 complement(759550..760068) 1 NC_011072.1 IS1167 transposase 760068 6480062 SPG_0785 Streptococcus pneumoniae G54 IS1167 transposase YP_002037498.1 759550 R 512566 CDS YP_002037499.1 194398381 6479235 complement(760349..760867) 1 NC_011072.1 IS1167 transposase 760867 6479235 SPG_0786 Streptococcus pneumoniae G54 IS1167 transposase YP_002037499.1 760349 R 512566 CDS YP_002037500.1 194398172 6478744 761060..761557 1 NC_011072.1 hypothetical protein 761557 6478744 SPG_0787 Streptococcus pneumoniae G54 hypothetical protein YP_002037500.1 761060 D 512566 CDS YP_002037501.1 194397860 6480733 761557..763212 1 NC_011072.1 catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the tau chain serves as a scaffold to help in the dimerizaton of the alpha,epsilon and theta core complex; the gamma chain seems to interact with the delta and delta' subunits to transfer the beta subunit on the DNA; DNA polymerase III subunits gamma and tau 763212 dnaX 6480733 dnaX Streptococcus pneumoniae G54 DNA polymerase III subunits gamma and tau YP_002037501.1 761557 D 512566 CDS YP_002037502.1 194397511 6480747 763312..763434 1 NC_011072.1 hypothetical protein 763434 6480747 SPG_0789 Streptococcus pneumoniae G54 hypothetical protein YP_002037502.1 763312 D 512566 CDS YP_002037503.1 194397141 6479234 763584..764354 1 NC_011072.1 identified by match to protein family HMM PF00005; match to protein family HMM TIGR01978; FeS assembly ATPase SufC 764354 6479234 SPG_0790 Streptococcus pneumoniae G54 FeS assembly ATPase SufC YP_002037503.1 763584 D 512566 CDS YP_002037504.1 194398657 6479941 764382..765644 1 NC_011072.1 identified by match to protein family HMM PF01458; match to protein family HMM TIGR01981; FeS assembly protein SufD 765644 6479941 SPG_0791 Streptococcus pneumoniae G54 FeS assembly protein SufD YP_002037504.1 764382 D 512566 CDS YP_002037505.1 194398383 6478923 765655..766881 1 NC_011072.1 identified by match to protein family HMM PF00266; match to protein family HMM PF01212; match to protein family HMM TIGR01979; cysteine desulfurase 766881 6478923 SPG_0792 Streptococcus pneumoniae G54 cysteine desulfurase YP_002037505.1 765655 D 512566 CDS YP_002037506.1 194397770 6479309 766868..767308 1 NC_011072.1 identified by match to protein family HMM PF01592; match to protein family HMM TIGR01994; NifU family protein 767308 6479309 SPG_0793 Streptococcus pneumoniae G54 NifU family protein YP_002037506.1 766868 D 512566 CDS YP_002037507.1 194397395 6480341 767362..768774 1 NC_011072.1 identified by match to protein family HMM PF01458; match to protein family HMM TIGR01980; FeS assembly protein SufB 768774 6480341 SPG_0794 Streptococcus pneumoniae G54 FeS assembly protein SufB YP_002037507.1 767362 D 512566 CDS YP_002037508.1 194396776 6480531 complement(769005..770246) 1 NC_011072.1 identified by match to protein family HMM PF00144; match to protein family HMM PF00768; match to protein family HMM PF07943; penicillin-binding protein 3, D-alanyl-D-alanine carboxypeptidase 770246 6480531 SPG_0795 Streptococcus pneumoniae G54 penicillin-binding protein 3, D-alanyl-D-alanine carboxypeptidase YP_002037508.1 769005 R 512566 CDS YP_002037509.1 194398662 6479916 770349..771458 1 NC_011072.1 identified by match to protein family HMM PF01594; hypothetical protein 771458 6479916 SPG_0796 Streptococcus pneumoniae G54 hypothetical protein YP_002037509.1 770349 D 512566 CDS YP_002037510.1 194398234 6480685 772871..773611 1 NC_011072.1 identified by similarity to GB:AAK75002.1; match to protein family HMM PF00455; match to protein family HMM PF08220; match to protein family HMM PF08279; transcriptional repressor fructose operon 773611 6480685 SPG_0799 Streptococcus pneumoniae G54 transcriptional repressor fructose operon YP_002037510.1 772871 D 512566 CDS YP_002037511.1 194397626 6479295 773608..774519 1 NC_011072.1 identified by match to protein family HMM PF00294; match to protein family HMM TIGR03168; 1-phosphofructokinase 774519 6479295 SPG_0800 Streptococcus pneumoniae G54 1-phosphofructokinase YP_002037511.1 773608 D 512566 CDS YP_002037512.1 194398028 6478905 774516..776468 1 NC_011072.1 identified by match to protein family HMM PF00359; match to protein family HMM PF02378; match to protein family HMM PF02379; match to protein family HMM TIGR00829; match to protein family HMM TIGR00848; match to protein family HMM TIGR01427; PTS system transporter subunit IIBCA 776468 6478905 SPG_0801 Streptococcus pneumoniae G54 PTS system transporter subunit IIBCA YP_002037512.1 774516 D 512566 CDS YP_002037513.1 194397735 6479241 776489..776638 1 NC_011072.1 identified by glimmer; putative; hypothetical protein 776638 6479241 SPG_0802 Streptococcus pneumoniae G54 hypothetical protein YP_002037513.1 776489 D 512566 CDS YP_002037514.1 194397074 6480438 776554..778857 1 NC_011072.1 identified by match to protein family HMM PF01580; FtsK/SpoIIIE family 778857 6480438 SPG_0803 Streptococcus pneumoniae G54 FtsK/SpoIIIE family YP_002037514.1 776554 D 512566 CDS YP_002037515.1 194396835 6479821 complement(778902..779330) 1 NC_011072.1 hypothetical protein 779330 6479821 SPG_0804 Streptococcus pneumoniae G54 hypothetical protein YP_002037515.1 778902 R 512566 CDS YP_002037516.1 194397347 6478801 779468..780610 1 NC_011072.1 identified by match to protein family HMM PF00266; class V aminotransferase 780610 6478801 SPG_0805 Streptococcus pneumoniae G54 class V aminotransferase YP_002037516.1 779468 D 512566 CDS YP_002037517.1 194398118 6480585 780619..781833 1 NC_011072.1 Required for the synthesis of the thiazole moiety; thiamine biosynthesis protein ThiI 781833 thiI 6480585 thiI Streptococcus pneumoniae G54 thiamine biosynthesis protein ThiI YP_002037517.1 780619 D 512566 CDS YP_002037518.1 194398562 6480241 781968..782540 1 NC_011072.1 contains potential frameshift; identified by glimmer; putative; hypothetical protein 782540 6480241 SPG_0807 Streptococcus pneumoniae G54 hypothetical protein YP_002037518.1 781968 D 512566 CDS YP_002037519.1 194398104 6479120 782599..782781 1 NC_011072.1 contains potential frameshift; hypothetical protein 782781 6479120 SPG_0808 Streptococcus pneumoniae G54 hypothetical protein YP_002037519.1 782599 D 512566 CDS YP_002037520.1 194398577 6479682 782803..783138 1 NC_011072.1 hypothetical protein 783138 6479682 SPG_0809 Streptococcus pneumoniae G54 hypothetical protein YP_002037520.1 782803 D 512566 CDS YP_002037521.1 194397836 6479183 783138..783542 1 NC_011072.1 hypothetical protein 783542 6479183 SPG_0810 Streptococcus pneumoniae G54 hypothetical protein YP_002037521.1 783138 D 512566 CDS YP_002037522.1 194398162 6480352 783555..784721 1 NC_011072.1 identified by glimmer; putative; hypothetical protein 784721 6480352 SPG_0811 Streptococcus pneumoniae G54 hypothetical protein YP_002037522.1 783555 D 512566 CDS YP_002037523.1 194396843 6480806 785229..786722 1 NC_011072.1 identified by similarity to GB:AAK99594.1; match to protein family HMM PF02384; type I restriction-modification system subunit M 786722 6480806 SPG_0812 Streptococcus pneumoniae G54 type I restriction-modification system subunit M YP_002037523.1 785229 D 512566 CDS YP_002037524.1 194397224 6478697 786735..787856 1 NC_011072.1 identified by match to protein family HMM PF01420; type I restriction-modification system subunit S 787856 6478697 SPG_0813 Streptococcus pneumoniae G54 type I restriction-modification system subunit S YP_002037524.1 786735 D 512566 CDS YP_002037525.1 194398155 6480796 787916..788152 1 NC_011072.1 hypothetical protein 788152 6480796 SPG_0814 Streptococcus pneumoniae G54 hypothetical protein YP_002037525.1 787916 D 512566 CDS YP_002037526.1 194398735 6479647 788149..788562 1 NC_011072.1 identified by match to protein family HMM PF05012; match to protein family HMM TIGR01550; prophage maintenance system killer protein 788562 6479647 SPG_0815 Streptococcus pneumoniae G54 prophage maintenance system killer protein YP_002037526.1 788149 D 512566 CDS YP_002037527.1 194397446 6478956 788680..789645 1 NC_011072.1 identified by match to protein family HMM PF00589; match to protein family HMM PF02899; phage integrase family integrase/recombinase 789645 6478956 SPG_0816 Streptococcus pneumoniae G54 phage integrase family integrase/recombinase YP_002037527.1 788680 D 512566 CDS YP_002037528.1 194397487 6480177 789679..790254 1 NC_011072.1 identified by match to protein family HMM PF01420; Type I restriction modification DNA specificity domain 790254 6480177 SPG_0817 Streptococcus pneumoniae G54 Type I restriction modification DNA specificity domain YP_002037528.1 789679 D 512566 CDS YP_002037529.1 194397826 6480637 790284..793634 1 NC_011072.1 identified by match to protein family HMM PF00270; match to protein family HMM PF00271; match to protein family HMM PF04313; match to protein family HMM PF04851; type I restriction-modification system subunit R 793634 6480637 SPG_0818 Streptococcus pneumoniae G54 type I restriction-modification system subunit R YP_002037529.1 790284 D 512566 CDS YP_002037530.1 194398737 6480450 complement(794221..794691) 1 NC_011072.1 identified by match to protein family HMM PF01316; match to protein family HMM PF02863; arginine repressor 794691 argR1 6480450 argR1 Streptococcus pneumoniae G54 arginine repressor YP_002037530.1 794221 R 512566 CDS YP_002037531.1 194397059 6479115 complement(794708..796981) 1 NC_011072.1 catalyzes the removal of N-terminal dipeptides when proline is the penultimate residue; x-prolyl-dipeptidyl aminopeptidase 796981 6479115 SPG_0820 Streptococcus pneumoniae G54 x-prolyl-dipeptidyl aminopeptidase YP_002037531.1 794708 R 512566 CDS YP_002037532.1 194397529 6479775 797329..800430 1 NC_011072.1 Catalyzes DNA-template-directed extension of the 3'-end of a DNA strand by one nucleotide at a time. Proposed to be responsible for the synthesis of the lagging strand. In the low GC gram positive bacteria this enzyme is less processive and more error prone than its counterpart in other bacteria.; DNA polymerase III DnaE 800430 dnaE 6479775 dnaE Streptococcus pneumoniae G54 DNA polymerase III DnaE YP_002037532.1 797329 D 512566 CDS YP_002037533.1 194397954 6478722 800513..801520 1 NC_011072.1 catalyzes the formation of D-fructose 1,6-bisphosphate from D-fructose 6-phosphate in glycolysis; 6-phosphofructokinase 801520 pfkA 6478722 pfkA Streptococcus pneumoniae G54 6-phosphofructokinase YP_002037533.1 800513 D 512566 CDS YP_002037534.1 194398235 6479101 801579..802136 1 NC_011072.1 contains potential frameshift; identified by match to protein family HMM PF00224; pyruvate kinase 802136 6479101 SPG_0823 Streptococcus pneumoniae G54 pyruvate kinase YP_002037534.1 801579 D 512566 CDS YP_002037535.1 194397757 6478870 802133..803083 1 NC_011072.1 contains potential frameshift; identified by match to protein family HMM PF00224; match to protein family HMM PF02887; match to protein family HMM TIGR01064; pyruvate kinase 803083 6478870 SPG_0824 Streptococcus pneumoniae G54 pyruvate kinase YP_002037535.1 802133 D 512566 CDS YP_002037536.1 194397260 6480445 complement(804157..804303) 1 NC_011072.1 identified by glimmer; putative; hypothetical protein 804303 6480445 SPG_0825 Streptococcus pneumoniae G54 hypothetical protein YP_002037536.1 804157 R 512566 CDS YP_002037537.1 194396718 6478935 804848..805720 1 NC_011072.1 hypothetical protein 805720 6478935 SPG_0826 Streptococcus pneumoniae G54 hypothetical protein YP_002037537.1 804848 D 512566 CDS YP_002037538.1 194398631 6479776 complement(805827..806210) 1 NC_011072.1 degenarate transposase 806210 6479776 SPG_0827 Streptococcus pneumoniae G54 degenarate transposase YP_002037538.1 805827 R 512566 CDS YP_002037539.1 194398027 6478944 806353..806664 1 NC_011072.1 hypothetical protein 806664 6478944 SPG_0828 Streptococcus pneumoniae G54 hypothetical protein YP_002037539.1 806353 D 512566 CDS YP_002037540.1 194397944 6479240 806668..807384 1 NC_011072.1 hypothetical protein 807384 6479240 SPG_0829 Streptococcus pneumoniae G54 hypothetical protein YP_002037540.1 806668 D 512566 CDS YP_002037541.1 194397454 6479075 complement(807513..808328) 1 NC_011072.1 identified by glimmer; putative; hypothetical protein 808328 6479075 SPG_0830 Streptococcus pneumoniae G54 hypothetical protein YP_002037541.1 807513 R 512566 CDS YP_002037542.1 194396691 6480469 complement(808325..809230) 1 NC_011072.1 identified by match to protein family HMM PF03773; hypothetical protein 809230 6480469 SPG_0831 Streptococcus pneumoniae G54 hypothetical protein YP_002037542.1 808325 R 512566 CDS YP_002037543.1 194397046 6479730 complement(809231..809362) 1 NC_011072.1 hypothetical protein 809362 6479730 SPG_0832 Streptococcus pneumoniae G54 hypothetical protein YP_002037543.1 809231 R 512566 CDS YP_002037544.1 194398593 6479763 809642..811771 1 NC_011072.1 identified by similarity to GB:AAK99612.1; match to protein family HMM PF00575; S1 RNA binding domain 811771 6479763 SPG_0833 Streptococcus pneumoniae G54 S1 RNA binding domain YP_002037544.1 809642 D 512566 CDS YP_002037545.1 194398111 6478939 812035..812187 1 NC_011072.1 identified by glimmer; putative; hypothetical protein 812187 6478939 SPG_0834 Streptococcus pneumoniae G54 hypothetical protein YP_002037545.1 812035 D 512566 CDS YP_002037546.1 194397430 6480481 812266..812538 1 NC_011072.1 identified by match to protein family HMM PF04024; hypothetical protein 812538 6480481 SPG_0835 Streptococcus pneumoniae G54 hypothetical protein YP_002037546.1 812266 D 512566 CDS YP_002037547.1 194396837 6480044 813512..814270 1 NC_011072.1 identified by match to protein family HMM PF00005; match to protein family HMM TIGR03608; ABC transporter ATP-binding protein 814270 6480044 SPG_0836 Streptococcus pneumoniae G54 ABC transporter ATP-binding protein YP_002037547.1 813512 D 512566 CDS YP_002037548.1 194397322 6478856 814272..816260 1 NC_011072.1 identified by match to protein family HMM PF02687; ABC transporter permease 816260 6478856 SPG_0837 Streptococcus pneumoniae G54 ABC transporter permease YP_002037548.1 814272 D 512566 CDS YP_002037549.1 194396693 6480219 complement(816302..816892) 1 NC_011072.1 identified by match to protein family HMM PF01988; hypothetical protein 816892 6480219 SPG_0838 Streptococcus pneumoniae G54 hypothetical protein YP_002037549.1 816302 R 512566 CDS YP_002037550.1 194397145 6479782 complement(816918..818015) 1 NC_011072.1 identified by match to protein family HMM PF00665; IS1239 transposase 818015 6479782 SPG_0839 Streptococcus pneumoniae G54 IS1239 transposase YP_002037550.1 816918 R 512566 CDS YP_002037551.1 194398188 6479087 818630..820105 1 NC_011072.1 identified by match to protein family HMM PF00266; match to protein family HMM PF01212; match to protein family HMM PF01276; match to protein family HMM PF03711; arginine decarboxylase 820105 cad 6479087 cad Streptococcus pneumoniae G54 arginine decarboxylase YP_002037551.1 818630 D 512566 CDS YP_002037552.1 194398518 6480343 complement(820071..820196) 1 NC_011072.1 hypothetical protein 820196 6480343 SPG_0840 Streptococcus pneumoniae G54 hypothetical protein YP_002037552.1 820071 R 512566 CDS YP_002037553.1 194397274 6480794 complement(820228..821358) 1 NC_011072.1 identified by match to protein family HMM PF02371; transposase 821358 6480794 SPG_0842 Streptococcus pneumoniae G54 transposase YP_002037553.1 820228 R 512566 CDS YP_002037554.1 194397341 6479548 821445..821582 1 NC_011072.1 identified by glimmer; putative; hypothetical protein 821582 6479548 SPG_0843 Streptococcus pneumoniae G54 hypothetical protein YP_002037554.1 821445 D 512566 CDS YP_002037555.1 194396869 6480094 821613..822473 1 NC_011072.1 catalyzes the formation of spermidine from putrescine and S-adenosylmethioninamine; spermidine synthase 822473 speE 6480094 speE Streptococcus pneumoniae G54 spermidine synthase YP_002037555.1 821613 D 512566 CDS YP_002037556.1 194398288 6478836 822470..823729 1 NC_011072.1 identified by match to protein family HMM PF03435; saccharopine dehydrogenase 823729 6478836 SPG_0845 Streptococcus pneumoniae G54 saccharopine dehydrogenase YP_002037556.1 822470 D 512566 CDS YP_002037557.1 194397835 6479010 823729..824856 1 NC_011072.1 identified by match to protein family HMM PF00278; match to protein family HMM TIGR01047; carboxynorspermidine decarboxylase 824856 nspC 6479010 nspC Streptococcus pneumoniae G54 carboxynorspermidine decarboxylase YP_002037557.1 823729 D 512566 CDS YP_002037558.1 194398758 6480351 824853..825992 1 NC_011072.1 catalyzes the formation of carbamoylputrescine from agmatine in the arginine decarboxylase pathway of putrescine biosynthesis; agmatine deiminase 825992 6480351 SPG_0847 Streptococcus pneumoniae G54 agmatine deiminase YP_002037558.1 824853 D 512566 CDS YP_002037559.1 194398116 6480698 825949..826824 1 NC_011072.1 identified by match to protein family HMM PF00795; match to protein family HMM TIGR03381; N-carbamoylputrescine amidase 826824 6480698 SPG_0848 Streptococcus pneumoniae G54 N-carbamoylputrescine amidase YP_002037559.1 825949 D 512566 CDS YP_002037560.1 194398337 6480646 complement(827005..827814) 1 NC_011072.1 identified by match to protein family HMM PF00702; match to protein family HMM PF05116; match to protein family HMM PF08282; match to protein family HMM TIGR00099; match to protein family HMM TIGR01484; Cof family protein 827814 6480646 SPG_0849 Streptococcus pneumoniae G54 Cof family protein YP_002037560.1 827005 R 512566 CDS YP_002037561.1 194397179 6480506 828086..828307 1 NC_011072.1 hypothetical protein 828307 6480506 SPG_0850 Streptococcus pneumoniae G54 hypothetical protein YP_002037561.1 828086 D 512566 CDS YP_002037562.1 194397383 6479100 828361..829032 1 NC_011072.1 identified by match to protein family HMM PF02517; CAAX amino terminal protease family 829032 6479100 SPG_0851 Streptococcus pneumoniae G54 CAAX amino terminal protease family YP_002037562.1 828361 D 512566 CDS YP_002037563.1 194397719 6480421 complement(829083..829280) 1 NC_011072.1 hypothetical protein 829280 6480421 SPG_0852 Streptococcus pneumoniae G54 hypothetical protein YP_002037563.1 829083 R 512566 CDS YP_002037564.1 194397501 6480129 829273..830181 1 NC_011072.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466; regulator of CbpE 830181 smrC 6480129 smrC Streptococcus pneumoniae G54 regulator of CbpE YP_002037564.1 829273 D 512566 CDS YP_002037565.1 194397876 6479263 830178..830639 1 NC_011072.1 lipoprotein signal peptidase; integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis; lipoprotein signal peptidase 830639 6479263 SPG_0854 Streptococcus pneumoniae G54 lipoprotein signal peptidase YP_002037565.1 830178 D 512566 CDS YP_002037566.1 194398681 6480732 830629..831516 1 NC_011072.1 identified by match to protein family HMM PF00849; match to protein family HMM PF01479; match to protein family HMM TIGR00005; ribosomal large subunit pseudouridine synthase D 831516 6480732 SPG_0855 Streptococcus pneumoniae G54 ribosomal large subunit pseudouridine synthase D YP_002037566.1 830629 D 512566 CDS YP_002037567.1 194397033 6478968 831519..833402 1 NC_011072.1 identified by match to protein family HMM PF00753; match to protein family HMM PF01473; choline binding protein E 833402 cbpE 6478968 cbpE Streptococcus pneumoniae G54 choline binding protein E YP_002037567.1 831519 D 512566 CDS YP_002037568.1 194397160 6480501 833503..834090 1 NC_011072.1 contains potential frameshift; identified by match to protein family HMM PF00696; match to protein family HMM TIGR01027; glutamate 5-kinase 834090 6480501 SPG_0857 Streptococcus pneumoniae G54 glutamate 5-kinase YP_002037568.1 833503 D 512566 CDS YP_002037569.1 194397657 6479274 834062..834613 1 NC_011072.1 contains potential frameshift; identified by match to protein family HMM PF01472; glutamate 5-kinase 834613 6479274 SPG_0858 Streptococcus pneumoniae G54 glutamate 5-kinase YP_002037569.1 834062 D 512566 CDS YP_002037570.1 194398438 6479070 834623..835885 1 NC_011072.1 Catalyzes the phosphorylation of L-glutamate during the proline biosynthesis pathway; gamma-glutamyl phosphate reductase 835885 proA 6479070 proA Streptococcus pneumoniae G54 gamma-glutamyl phosphate reductase YP_002037570.1 834623 D 512566 CDS YP_002037571.1 194397965 6480589 835889..836686 1 NC_011072.1 identified by match to protein family HMM PF01210; match to protein family HMM PF03807; match to protein family HMM TIGR00112; pyrroline-5-carboxylate reductase 836686 proC 6480589 proC Streptococcus pneumoniae G54 pyrroline-5-carboxylate reductase YP_002037571.1 835889 D 512566 CDS YP_002037572.1 194397492 6479365 836906..837544 1 NC_011072.1 catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to thymidine monophosphate (dTMP) to form thymidine diphosphate (dTDP); thymidylate kinase 837544 tmk 6479365 tmk Streptococcus pneumoniae G54 thymidylate kinase YP_002037572.1 836906 D 512566 CDS YP_002037573.1 194397015 6480228 837541..838431 1 NC_011072.1 catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the delta' subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA.; DNA polymerase III subunit delta' 838431 holB 6480228 holB Streptococcus pneumoniae G54 DNA polymerase III subunit delta' YP_002037573.1 837541 D 512566 CDS YP_002037574.1 194397201 6480011 838471..838788 1 NC_011072.1 in Bacillus subtilis this protein is involved in the negative regulation of DNA replication initiation; interacts with DnaN and DnaA; DNA replication intiation control protein YabA 838788 6480011 SPG_0863 Streptococcus pneumoniae G54 DNA replication intiation control protein YabA YP_002037574.1 838471 D 512566 CDS YP_002037575.1 194397823 6480771 838791..839660 1 NC_011072.1 identified by match to protein family HMM PF00590; match to protein family HMM TIGR00096; hypothetical protein 839660 6480771 SPG_0864 Streptococcus pneumoniae G54 hypothetical protein YP_002037575.1 838791 D 512566 CDS YP_002037576.1 194397056 6480601 839887..840405 1 NC_011072.1 identified by match to protein family HMM PF08020; hypothetical protein 840405 6480601 SPG_0865 Streptococcus pneumoniae G54 hypothetical protein YP_002037576.1 839887 D 512566 CDS YP_002037577.1 194397683 6480042 840514..840651 1 NC_011072.1 phage protein, point mutation 840651 6480042 SPG_0866 Streptococcus pneumoniae G54 phage protein, point mutation YP_002037577.1 840514 D 512566 CDS YP_002037578.1 194398355 6479340 840658..841161 1 NC_011072.1 phage protein, point mutation 841161 6479340 SPG_0868 Streptococcus pneumoniae G54 phage protein, point mutation YP_002037578.1 840658 D 512566 CDS YP_002037579.1 194396824 6479970 complement(841150..841539) 1 NC_011072.1 identified by match to protein family HMM PF01609; transposase 841539 6479970 SPG_0867 Streptococcus pneumoniae G54 transposase YP_002037579.1 841150 R 512566 CDS YP_002037580.1 194398400 6478934 complement(841767..841955) 1 NC_011072.1 degenarate transposase 841955 6478934 SPG_0869 Streptococcus pneumoniae G54 degenarate transposase YP_002037580.1 841767 R 512566 CDS YP_002037581.1 194397933 6479171 842449..843783 1 NC_011072.1 TrmFO; Gid; glucose-inhibited division protein; similar to GidA; the gene from Bacillus subtilis encodes a tRNA-methyltransferase that utilizes folate as the carbon donor and bound flavin as reductant; modifies tRNA at position 54 (uridine) of the T-psi loop to form a C5-methyluridine; tRNA (uracil-5-)-methyltransferase Gid 843783 6479171 SPG_0870 Streptococcus pneumoniae G54 tRNA (uracil-5-)-methyltransferase Gid YP_002037581.1 842449 D 512566 CDS YP_002037582.1 194398088 6478670 843867..844604 1 NC_011072.1 Catalyzes the phosphorylation of UMP to UDP; uridylate kinase 844604 pyrH 6478670 pyrH Streptococcus pneumoniae G54 uridylate kinase YP_002037582.1 843867 D 512566 CDS YP_002037583.1 194397625 6478949 844613..845170 1 NC_011072.1 Rrf; Frr; ribosome-recycling factor; release factor 4; RF4; recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G; A GTPase-dependent process results in release of 50S from 70S; inhibited by release factor RF-1; essential for viability; structurally similar to tRNAs; ribosome recycling factor 845170 frr 6478949 frr Streptococcus pneumoniae G54 ribosome recycling factor YP_002037583.1 844613 D 512566 CDS YP_002037584.1 194398706 6478904 845191..846084 1 NC_011072.1 hypothetical protein 846084 6478904 SPG_0873 Streptococcus pneumoniae G54 hypothetical protein YP_002037584.1 845191 D 512566 CDS YP_002037585.1 194398255 6479057 846093..846308 1 NC_011072.1 identified by match to protein family HMM PF06855; hypothetical protein 846308 6479057 SPG_0874 Streptococcus pneumoniae G54 hypothetical protein YP_002037585.1 846093 D 512566 CDS YP_002037586.1 194397204 6479282 846394..847398 1 NC_011072.1 identified by match to protein family HMM PF02562; PhoH family protein 847398 6479282 SPG_0875 Streptococcus pneumoniae G54 PhoH family protein YP_002037586.1 846394 D 512566 CDS YP_002037587.1 194396805 6480090 847506..848075 1 NC_011072.1 identified by match to protein family HMM PF00583; GNAT family acetyltransferase 848075 6480090 SPG_0876 Streptococcus pneumoniae G54 GNAT family acetyltransferase YP_002037587.1 847506 D 512566 CDS YP_002037588.1 194397453 6479091 848143..848793 1 NC_011072.1 identified by match to protein family HMM PF00633; match to protein family HMM TIGR00426; match to protein family HMM TIGR01259; competence protein ComEA 848793 comEA 6479091 comEA Streptococcus pneumoniae G54 competence protein ComEA YP_002037588.1 848143 D 512566 CDS YP_002037589.1 194396981 6480098 848777..851017 1 NC_011072.1 identified by match to protein family HMM PF03772; match to protein family HMM TIGR00360; match to protein family HMM TIGR00361; competence protein ComEC 851017 comEC 6480098 comEC Streptococcus pneumoniae G54 competence protein ComEC YP_002037589.1 848777 D 512566 CDS YP_002037590.1 194397590 6479858 851238..851384 1 NC_011072.1 hypothetical protein 851384 6479858 SPG_0879 Streptococcus pneumoniae G54 hypothetical protein YP_002037590.1 851238 D 512566 CDS YP_002037591.1 194397120 6479154 851416..852003 1 NC_011072.1 identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 852003 6479154 SPG_0880 Streptococcus pneumoniae G54 ABC transporter ATP-binding protein YP_002037591.1 851416 D 512566 CDS YP_002037592.1 194398563 6479848 852007..853167 1 NC_011072.1 identified by glimmer; putative; hypothetical protein 853167 6479848 SPG_0881 Streptococcus pneumoniae G54 hypothetical protein YP_002037592.1 852007 D 512566 CDS YP_002037593.1 194398067 6479121 complement(853206..853340) 1 NC_011072.1 identified by glimmer; putative; hypothetical protein 853340 6479121 SPG_0882 Streptococcus pneumoniae G54 hypothetical protein YP_002037593.1 853206 R 512566 CDS YP_002037594.1 194397268 6479399 853469..854026 1 NC_011072.1 IF-3 has several functions that are required and promote translation initiation including; preventing association of 70S by binding to 30S; monitoring codon-anticodon interactions by promoting disassociation of fMet-tRNA(fMet) from initiation complexes formed on leaderless mRNAs or incorrectly bound noninitiatior tRNAs and complexes with noncanonical start sites; stimulates codon-anticodon interactions at P-site; involved in moving mRNA to the P-site; and in recycling subunits; translation initiation factor IF-3 854026 infC 6479399 infC Streptococcus pneumoniae G54 translation initiation factor IF-3 YP_002037594.1 853469 D 512566 CDS YP_002037595.1 194396802 6479180 854059..854259 1 NC_011072.1 identified by match to protein family HMM PF01632; match to protein family HMM TIGR00001; 50S ribosomal protein L35 854259 rpmI 6479180 rpmI Streptococcus pneumoniae G54 50S ribosomal protein L35 YP_002037595.1 854059 D 512566 CDS YP_002037596.1 194398245 6478849 854311..854670 1 NC_011072.1 binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit; 50S ribosomal protein L20 854670 rplT 6478849 rplT Streptococcus pneumoniae G54 50S ribosomal protein L20 YP_002037596.1 854311 D 512566 CDS YP_002037597.1 194397774 6479499 854728..855108 1 NC_011072.1 identified by match to protein family HMM PF00903; lactoylglutathione lyase 855108 lguL 6479499 lguL Streptococcus pneumoniae G54 lactoylglutathione lyase YP_002037597.1 854728 D 512566 CDS YP_002037598.1 194397027 6480527 855358..856158 1 NC_011072.1 responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the pyrD subunit to the ultimate electron acceptor NAD(+); dihydroorotate dehydrogenase electron transfer subunit 856158 pyrDII 6480527 pyrDII Streptococcus pneumoniae G54 dihydroorotate dehydrogenase electron transfer subunit YP_002037598.1 855358 D 512566 CDS YP_002037599.1 194398689 6479627 856169..857107 1 NC_011072.1 catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway, using a flavin nucleotide as an essential cofactor; subclass 1B is a heterotetramer consisting of two PyrDB subunits, similar to the PyrDA subunits and two PyrK subunits; dihydroorotate dehydrogenase 1B 857107 6479627 SPG_0888 Streptococcus pneumoniae G54 dihydroorotate dehydrogenase 1B YP_002037599.1 856169 D 512566 CDS YP_002037600.1 194398062 6479000 857206..859314 1 NC_011072.1 identified by match to protein family HMM PF01473; match to protein family HMM PF01832; endo-beta-N-acetylglucosaminidase 859314 lytB 6479000 lytB Streptococcus pneumoniae G54 endo-beta-N-acetylglucosaminidase YP_002037600.1 857206 D 512566 CDS YP_002037601.1 194398513 6479038 complement(859375..861030) 1 NC_011072.1 identified by match to protein family HMM PF05670; match to protein family HMM PF05833; fibronectin-binding protein-like protein A 861030 flpA 6479038 flpA Streptococcus pneumoniae G54 fibronectin-binding protein-like protein A YP_002037601.1 859375 R 512566 CDS YP_002037602.1 194397080 6480213 861135..861632 1 NC_011072.1 identified by match to protein family HMM PF02130; match to protein family HMM TIGR00043; putative metalloprotease 861632 6480213 SPG_0891 Streptococcus pneumoniae G54 putative metalloprotease YP_002037602.1 861135 D 512566 CDS YP_002037603.1 194397582 6479926 861613..862008 1 NC_011072.1 identified by match to protein family HMM PF01219; diacylglycerol kinase 862008 dgkA 6479926 dgkA Streptococcus pneumoniae G54 diacylglycerol kinase YP_002037603.1 861613 D 512566 CDS YP_002037604.1 194397601 6478987 862025..862924 1 NC_011072.1 Era; Escherichia coli Ras-like protein; Bex; Bacillus Era-complementing segment; essential protein in Escherichia coli that is involved in many cellular processes; GTPase; binds the cell membrane through apparent C-terminal domain; mutants are arrested during the cell cycle; Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome; GTP-binding protein Era 862924 era 6478987 era Streptococcus pneumoniae G54 GTP-binding protein Era YP_002037604.1 862025 D 512566 CDS YP_002037605.1 194398197 6479345 862973..863797 1 NC_011072.1 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases; formamidopyrimidine-DNA glycosylase 863797 fpg 6479345 fpg Streptococcus pneumoniae G54 formamidopyrimidine-DNA glycosylase YP_002037605.1 862973 D 512566 CDS YP_002037606.1 194396679 6480516 863797..864402 1 NC_011072.1 catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; involved in coenzyme A biosynthesis; dephospho-CoA kinase 864402 coaE 6480516 coaE Streptococcus pneumoniae G54 dephospho-CoA kinase YP_002037606.1 863797 D 512566 CDS YP_002037607.1 194397261 6480301 864389..865588 1 NC_011072.1 identified by match to protein family HMM PF07690; multi-drug resistance efflux pump 865588 6480301 SPG_0896 Streptococcus pneumoniae G54 multi-drug resistance efflux pump YP_002037607.1 864389 D 512566 CDS YP_002037608.1 194397443 6478936 865777..866010 1 NC_011072.1 identified by match to protein family HMM PF03840; match to protein family HMM TIGR00810; preprotein translocase subunit SecG 866010 secG 6478936 secG Streptococcus pneumoniae G54 preprotein translocase subunit SecG YP_002037608.1 865777 D 512566 CDS YP_002037609.1 194397729 6480348 866112..868466 1 NC_011072.1 also known as vacB; identified by match to protein family HMM PF00575; match to protein family HMM PF00773; match to protein family HMM PF08206; match to protein family HMM TIGR00358; match to protein family HMM TIGR02063; ribonuclease R 868466 rnr 6480348 rnr Streptococcus pneumoniae G54 ribonuclease R YP_002037609.1 866112 D 512566 CDS YP_002037610.1 194396988 6480416 868429..868896 1 NC_011072.1 binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation; SsrA-binding protein 868896 smpB 6480416 smpB Streptococcus pneumoniae G54 SsrA-binding protein YP_002037610.1 868429 D 512566 CDS YP_002037611.1 194397299 6480092 868912..869772 1 NC_011072.1 with TehA confers resistance to tellurite; tellurite resistance protein TehB 869772 tehB 6480092 tehB Streptococcus pneumoniae G54 tellurite resistance protein TehB YP_002037611.1 868912 D 512566 CDS YP_002037612.1 194397937 6478960 869845..870798 1 NC_011072.1 identified by match to protein family HMM PF06054; competence protein CoiA 870798 coiA 6478960 coiA Streptococcus pneumoniae G54 competence protein CoiA YP_002037612.1 869845 D 512566 CDS YP_002037613.1 194397778 6479445 870817..872619 1 NC_011072.1 identified by match to protein family HMM PF01432; match to protein family HMM PF08439; match to protein family HMM TIGR00181; group B oligopeptidase PepB 872619 pepB 6479445 pepB Streptococcus pneumoniae G54 group B oligopeptidase PepB YP_002037613.1 870817 D 512566 CDS YP_002037614.1 194398372 6480435 872621..873334 1 NC_011072.1 identified by match to protein family HMM PF01596; match to protein family HMM PF08241; hypothetical protein 873334 6480435 SPG_0903 Streptococcus pneumoniae G54 hypothetical protein YP_002037614.1 872621 D 512566 CDS YP_002037615.1 194397602 6479169 873401..874060 1 NC_011072.1 contains potential frameshift; foldase protein PrsA 874060 6479169 SPG_0904 Streptococcus pneumoniae G54 foldase protein PrsA YP_002037615.1 873401 D 512566 CDS YP_002037616.1 194398249 6479346 874044..874169 1 NC_011072.1 contains potential frameshift; foldase protein PrsA 874169 6479346 SPG_0905 Streptococcus pneumoniae G54 foldase protein PrsA YP_002037616.1 874044 D 512566 CDS YP_002037617.1 194397627 6479047 874205..874336 1 NC_011072.1 contains potential frameshift; foldase protein PrsA 874336 6479047 SPG_0906 Streptococcus pneumoniae G54 foldase protein PrsA YP_002037617.1 874205 D 512566 CDS YP_002037618.1 194397173 6478906 complement(874525..874794) 1 NC_011072.1 IS3-Spn1 transposase 874794 6478906 SPG_0907 Streptococcus pneumoniae G54 IS3-Spn1 transposase YP_002037618.1 874525 R 512566 CDS YP_002037619.1 194397951 6479384 complement(874794..874928) 1 NC_011072.1 IS3-Spn1 transposase 874928 6479384 SPG_0908 Streptococcus pneumoniae G54 IS3-Spn1 transposase YP_002037619.1 874794 R 512566 CDS YP_002037620.1 194397102 6478684 complement(875555..876175) 1 NC_011072.1 identified by match to protein family HMM PF00300; phosphoglycerate mutase family protein 876175 6478684 SPG_0909 Streptococcus pneumoniae G54 phosphoglycerate mutase family protein YP_002037620.1 875555 R 512566 CDS YP_002037621.1 194397314 6479889 complement(876175..876657) 1 NC_011072.1 identified by match to protein family HMM PF04073; regulatory protein 876657 6479889 SPG_0910 Streptococcus pneumoniae G54 regulatory protein YP_002037621.1 876175 R 512566 CDS YP_002037622.1 194397925 6479777 complement(876657..877499) 1 NC_011072.1 identified by match to protein family HMM PF04018; hypothetical protein 877499 6479777 SPG_0911 Streptococcus pneumoniae G54 hypothetical protein YP_002037622.1 876657 R 512566 CDS YP_002037623.1 194398033 6479298 complement(877594..878382) 1 NC_011072.1 identified by glimmer; putative; hypothetical protein 878382 6479298 SPG_0912 Streptococcus pneumoniae G54 hypothetical protein YP_002037623.1 877594 R 512566 CDS YP_002037624.1 194398604 6479065 878526..879905 1 NC_011072.1 forms a homotrimer; catalyzes the acetylation of glucosamine-1-phosphate and uridylation of N-acetylglucosamine-1-phosphate to produce UDP-GlcNAc; function in cell wall synthesis; bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase 879905 glmU 6479065 glmU Streptococcus pneumoniae G54 bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase YP_002037624.1 878526 D 512566 CDS YP_002037625.1 194396950 6479386 879915..880460 1 NC_011072.1 identified by match to protein family HMM PF00293; NUDIX family hydrolase 880460 6479386 SPG_0914 Streptococcus pneumoniae G54 NUDIX family hydrolase YP_002037625.1 879915 D 512566 CDS YP_002037626.1 194397609 6480201 880472..880786 1 NC_011072.1 hypothetical protein 880786 6480201 SPG_0915 Streptococcus pneumoniae G54 hypothetical protein YP_002037626.1 880472 D 512566 CDS YP_002037627.1 194397113 6479043 880803..881495 1 NC_011072.1 enables the cleavage of the glycosidic bond in both 5'-methylthioadenosine and S-adenosylhomocysteine; 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase 881495 6479043 SPG_0916 Streptococcus pneumoniae G54 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase YP_002037627.1 880803 D 512566 CDS YP_002037628.1 194397604 6479764 881572..882063 1 NC_011072.1 identified by match to protein family HMM PF04394; hypothetical protein 882063 6479764 SPG_0917 Streptococcus pneumoniae G54 hypothetical protein YP_002037628.1 881572 D 512566 CDS YP_002037629.1 194397817 6479361 882161..882751 1 NC_011072.1 3'-5' exonuclease of DNA polymerase III; DNA polymerase III subunit epsilon 882751 6479361 SPG_0918 Streptococcus pneumoniae G54 DNA polymerase III subunit epsilon YP_002037629.1 882161 D 512566 CDS YP_002037630.1 194397262 6480754 882760..884523 1 NC_011072.1 identified by match to protein family HMM PF03009; hypothetical protein 884523 6480754 SPG_0919 Streptococcus pneumoniae G54 hypothetical protein YP_002037630.1 882760 D 512566 CDS YP_002037631.1 194398232 6478937 884814..886160 1 NC_011072.1 identified by match to protein family HMM PF01609; IS1380-Spn1 transposase 886160 6478937 SPG_0920 Streptococcus pneumoniae G54 IS1380-Spn1 transposase YP_002037631.1 884814 D 512566 CDS YP_002037632.1 194398566 6479293 886445..886774 1 NC_011072.1 identified by match to protein family HMM PF01710; IS630-Spn1 transposase 886774 6479293 SPG_0921 Streptococcus pneumoniae G54 IS630-Spn1 transposase YP_002037632.1 886445 D 512566 CDS YP_002037633.1 194396687 6478814 887254..887454 1 NC_011072.1 hypothetical protein 887454 6478814 SPG_0922 Streptococcus pneumoniae G54 hypothetical protein YP_002037633.1 887254 D 512566 CDS YP_002037634.1 194397252 6480015 887479..887895 1 NC_011072.1 hypothetical protein 887895 6480015 SPG_0923 Streptococcus pneumoniae G54 hypothetical protein YP_002037634.1 887479 D 512566 CDS YP_002037635.1 194398148 6479792 888126..888833 1 NC_011072.1 identified by match to protein family HMM PF02683; cytochrome c-type biogenesis protein CcdA 888833 6479792 SPG_0924 Streptococcus pneumoniae G54 cytochrome c-type biogenesis protein CcdA YP_002037635.1 888126 D 512566 CDS YP_002037636.1 194398726 6479626 888844..889401 1 NC_011072.1 identified by match to protein family HMM PF00578; match to protein family HMM PF08534; thioredoxin family protein 889401 6479626 SPG_0925 Streptococcus pneumoniae G54 thioredoxin family protein YP_002037636.1 888844 D 512566 CDS YP_002037637.1 194398740 6479383 889775..891166 1 NC_011072.1 identified by match to protein family HMM PF00324; amino acid permease 891166 6479383 SPG_0926 Streptococcus pneumoniae G54 amino acid permease YP_002037637.1 889775 D 512566 CDS YP_002037638.1 194397276 6478925 891309..892226 1 NC_011072.1 identified by match to protein family HMM PF01297; adhesion lipoprotein 892226 6478925 SPG_0927 Streptococcus pneumoniae G54 adhesion lipoprotein YP_002037638.1 891309 D 512566 CDS YP_002037639.1 194397760 6479018 892234..894084 1 NC_011072.1 contains potential frameshift; identified by match to protein family HMM PF04270; match to protein family HMM TIGR01363; histidine triad protein D 894084 phtD 6479018 phtD Streptococcus pneumoniae G54 histidine triad protein D YP_002037639.1 892234 D 512566 CDS YP_002037640.1 194398648 6479675 894104..894781 1 NC_011072.1 contains potential frameshift; histidine triad protein D 894781 phtD 6479675 phtD Streptococcus pneumoniae G54 histidine triad protein D YP_002037640.1 894104 D 512566 CDS YP_002037641.1 194398203 6479504 894991..898110 1 NC_011072.1 contains potential frameshift; identified by match to protein family HMM PF04270; match to protein family HMM TIGR01363; histidine triad protein D 898110 phtD 6479504 phtD Streptococcus pneumoniae G54 histidine triad protein D YP_002037641.1 894991 D 512566 CDS YP_002037642.1 194397471 6478833 898940..899509 1 NC_011072.1 identified by match to protein family HMM PF04270; histidine triad protein E 899509 phtE 6478833 phtE Streptococcus pneumoniae G54 histidine triad protein E YP_002037642.1 898940 D 512566 CDS YP_002037643.1 194397520 6479634 899804..900433 1 NC_011072.1 identified by glimmer; putative; hypothetical protein 900433 6479634 SPG_0932 Streptococcus pneumoniae G54 hypothetical protein YP_002037643.1 899804 D 512566 CDS YP_002037644.1 194396921 6478989 complement(900469..900864) 1 NC_011072.1 contains potential frameshift; peptidase T 900864 6478989 SPG_0933 Streptococcus pneumoniae G54 peptidase T YP_002037644.1 900469 R 512566 CDS YP_002037645.1 194398734 6480586 complement(900842..901693) 1 NC_011072.1 contains potential frameshift; identified by match to protein family HMM PF07687; match to protein family HMM TIGR01882; peptidase T 901693 6480586 SPG_0934 Streptococcus pneumoniae G54 peptidase T YP_002037645.1 900842 R 512566 CDS YP_002037646.1 194398359 6478955 901940..902941 1 NC_011072.1 identified by match to protein family HMM PF00762; match to protein family HMM TIGR00109; ferrochelatase 902941 hemH 6478955 hemH Streptococcus pneumoniae G54 ferrochelatase YP_002037646.1 901940 D 512566 CDS YP_002037647.1 194397432 6480756 complement(902983..903360) 1 NC_011072.1 identified by match to protein family HMM PF01741; match to protein family HMM TIGR00220; large conductance mechanosensitive channel protein 903360 mscL 6480756 mscL Streptococcus pneumoniae G54 large conductance mechanosensitive channel protein YP_002037647.1 902983 R 512566 CDS YP_002037648.1 194396740 6480709 complement(903442..903873) 1 NC_011072.1 identified by match to protein family HMM PF04138; GtrA family protein 903873 6480709 SPG_0937 Streptococcus pneumoniae G54 GtrA family protein YP_002037648.1 903442 R 512566 CDS YP_002037649.1 194398633 6479669 903996..904505 1 NC_011072.1 identified by match to protein family HMM PF06177; hypothetical protein 904505 6479669 SPG_0938 Streptococcus pneumoniae G54 hypothetical protein YP_002037649.1 903996 D 512566 CDS YP_002037650.1 194398066 6480648 905020..906096 1 NC_011072.1 catalyzes the formation of 4-aspartyl phosphate from aspartate 4-semialdehyde; aspartate-semialdehyde dehydrogenase 906096 asd 6480648 asd Streptococcus pneumoniae G54 aspartate-semialdehyde dehydrogenase YP_002037650.1 905020 D 512566 CDS YP_002037651.1 194397731 6479398 906152..907087 1 NC_011072.1 catalyzes the formation of dihydrodipicolinate from L-aspartate 4-semialdehyde and pyruvate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate synthase 907087 dapA 6479398 dapA Streptococcus pneumoniae G54 dihydrodipicolinate synthase YP_002037651.1 906152 D 512566 CDS YP_002037652.1 194398466 6480418 complement(907134..908507) 1 NC_011072.1 in Escherichia coli this protein is involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2-thiouridine, which is found in the wobble position of some tRNAs and affects ribosomal frameshifting; shows potassium-dependent dimerization and GTP hydrolysis; also involved in regulation of glutamate-dependent acid resistance and activation of gadE; tRNA modification GTPase TrmE 908507 trmE 6480418 trmE Streptococcus pneumoniae G54 tRNA modification GTPase TrmE YP_002037652.1 907134 R 512566 CDS YP_002037653.1 194396952 6480786 complement(908645..908827) 1 NC_011072.1 4-OT; member of subfamily 5; forms a dimer; the function in the Escherichia coli cell is unknown; 4-oxalocrotonate tautomerase 908827 6480786 SPG_0943 Streptococcus pneumoniae G54 4-oxalocrotonate tautomerase YP_002037653.1 908645 R 512566 CDS YP_002037654.1 194397578 6479656 908951..909541 1 NC_011072.1 catalyzes the formation of thymidine 5'-phosphate from thymidine; thymidine kinase 909541 tdk 6479656 tdk Streptococcus pneumoniae G54 thymidine kinase YP_002037654.1 908951 D 512566 CDS YP_002037655.1 194398144 6479368 909538..910617 1 NC_011072.1 recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2; peptide chain release factor 1 910617 prfA 6479368 prfA Streptococcus pneumoniae G54 peptide chain release factor 1 YP_002037655.1 909538 D 512566 CDS YP_002037656.1 194398713 6480568 910617..911456 1 NC_011072.1 identified by match to protein family HMM PF05175; match to protein family HMM PF08241; match to protein family HMM PF08242; match to protein family HMM TIGR00536; methyltransferase, HemK family protein 911456 6480568 SPG_0946 Streptococcus pneumoniae G54 methyltransferase, HemK family protein YP_002037656.1 910617 D 512566 CDS YP_002037657.1 194397422 6479552 911440..912042 1 NC_011072.1 identified by match to protein family HMM PF01300; match to protein family HMM TIGR00057; Sua5/YciO/YrdC/YwlC family protein 912042 6479552 SPG_0947 Streptococcus pneumoniae G54 Sua5/YciO/YrdC/YwlC family protein YP_002037657.1 911440 D 512566 CDS YP_002037658.1 194397942 6479936 912044..912475 1 NC_011072.1 identified by match to protein family HMM PF00583; GNAT family acetyltransferase 912475 6479936 SPG_0948 Streptococcus pneumoniae G54 GNAT family acetyltransferase YP_002037658.1 912044 D 512566 CDS YP_002037659.1 194396966 6479492 912537..913793 1 NC_011072.1 catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate; serine hydroxymethyltransferase 913793 glyA 6479492 glyA Streptococcus pneumoniae G54 serine hydroxymethyltransferase YP_002037659.1 912537 D 512566 CDS YP_002037660.1 194396999 6480200 913801..914775 1 NC_011072.1 hypothetical protein 914775 6480200 SPG_0950 Streptococcus pneumoniae G54 hypothetical protein YP_002037660.1 913801 D 512566 CDS YP_002037661.1 194397861 6479689 914775..915389 1 NC_011072.1 hypothetical protein 915389 6479689 SPG_0951 Streptococcus pneumoniae G54 hypothetical protein YP_002037661.1 914775 D 512566 CDS YP_002037662.1 194397384 6480748 915463..916437 1 NC_011072.1 identified by match to protein family HMM PF06207; hypothetical protein 916437 6480748 SPG_0952 Streptococcus pneumoniae G54 hypothetical protein YP_002037662.1 915463 D 512566 CDS YP_002037663.1 194397238 6480557 916511..918142 1 NC_011072.1 identified by match to protein family HMM PF01938; match to protein family HMM PF05958; match to protein family HMM TIGR00479; 23S rRNA (uracil-5-)-methyltransferase RumA 918142 6480557 SPG_0953 Streptococcus pneumoniae G54 23S rRNA (uracil-5-)-methyltransferase RumA YP_002037663.1 916511 D 512566 CDS YP_002037664.1 194396743 6480322 918880..919098 1 NC_011072.1 hypothetical protein 919098 6480322 SPG_0954 Streptococcus pneumoniae G54 hypothetical protein YP_002037664.1 918880 D 512566 CDS YP_002037665.1 194398666 6479679 919102..919371 1 NC_011072.1 identified by glimmer; putative; hypothetical protein 919371 6479679 SPG_0955 Streptococcus pneumoniae G54 hypothetical protein YP_002037665.1 919102 D 512566 CDS YP_002037666.1 194398219 6478755 919492..920517 1 NC_011072.1 Ulijasz AT, J Bacteriol. 2004 Dec;186(23):8123-36; identified by match to protein family HMM PF01497; iron ABC transporter iron-binding protein 920517 piaA 6478755 piaA Streptococcus pneumoniae G54 iron ABC transporter iron-binding protein YP_002037666.1 919492 D 512566 CDS YP_002037667.1 194398421 6479522 920507..921514 1 NC_011072.1 Ulijasz AT, J Bacteriol. 2004 Dec;186(23):8123-36.; identified by match to protein family HMM PF01032; iron ABC transporter permease 921514 piaB 6479522 piaB Streptococcus pneumoniae G54 iron ABC transporter permease YP_002037667.1 920507 D 512566 CDS YP_002037668.1 194397962 6480364 921514..922521 1 NC_011072.1 Ulijasz AT, J Bacteriol. 2004 Dec;186(23):8123-36.; identified by match to protein family HMM PF01032; iron ABC transporter permease 922521 piaC 6480364 piaC Streptococcus pneumoniae G54 iron ABC transporter permease YP_002037668.1 921514 D 512566 CDS YP_002037669.1 194397230 6478915 922521..923315 1 NC_011072.1 Ulijasz AT, J Bacteriol. 2004 Dec;186(23):8123-36.; identified by match to protein family HMM PF00005; iron ABC transporter ATP-binding protein 923315 piaD 6478915 piaD Streptococcus pneumoniae G54 iron ABC transporter ATP-binding protein YP_002037669.1 922521 D 512566 CDS YP_002037670.1 194396844 6479911 924188..924502 1 NC_011072.1 hypothetical protein 924502 6479911 SPG_0960 Streptococcus pneumoniae G54 hypothetical protein YP_002037670.1 924188 D 512566 CDS YP_002037671.1 194397338 6478726 924812..926452 1 NC_011072.1 identified by match to protein family HMM PF03389; nickase 926452 6478726 SPG_0961 Streptococcus pneumoniae G54 nickase YP_002037671.1 924812 D 512566 CDS YP_002037672.1 194397812 6480706 926885..927412 1 NC_011072.1 hypothetical protein 927412 6480706 SPG_0962 Streptococcus pneumoniae G54 hypothetical protein YP_002037672.1 926885 D 512566 CDS YP_002037673.1 194397612 6480181 927539..928051 1 NC_011072.1 identified by match to protein family HMM TIGR01714; phage replisome organizer, N-terminal region 928051 6480181 SPG_0963 Streptococcus pneumoniae G54 phage replisome organizer, N-terminal region YP_002037673.1 927539 D 512566 CDS YP_002037674.1 194397806 6478932 928136..928267 1 NC_011072.1 hypothetical protein 928267 6478932 SPG_0964 Streptococcus pneumoniae G54 hypothetical protein YP_002037674.1 928136 D 512566 CDS YP_002037675.1 194398394 6480664 928951..929112 1 NC_011072.1 hypothetical protein 929112 6480664 SPG_0965 Streptococcus pneumoniae G54 hypothetical protein YP_002037675.1 928951 D 512566 CDS YP_002037676.1 194396865 6478857 929204..930883 1 NC_011072.1 identified by match to protein family HMM PF00239; match to protein family HMM PF07508; resolvase family protein site-specific recombinase 930883 6478857 SPG_0966 Streptococcus pneumoniae G54 resolvase family protein site-specific recombinase YP_002037676.1 929204 D 512566 CDS YP_002037677.1 194398042 6479451 931151..931717 1 NC_011072.1 identified by similarity to RF:ZP_00404330.1; hypothetical protein 931717 6479451 SPG_0967 Streptococcus pneumoniae G54 hypothetical protein YP_002037677.1 931151 D 512566 CDS YP_002037678.1 194398640 6479507 932038..932226 1 NC_011072.1 hypothetical protein 932226 6479507 SPG_0968 Streptococcus pneumoniae G54 hypothetical protein YP_002037678.1 932038 D 512566 CDS YP_002037679.1 194397043 6479077 932288..933046 1 NC_011072.1 hypothetical protein 933046 6479077 SPG_0969 Streptococcus pneumoniae G54 hypothetical protein YP_002037679.1 932288 D 512566 CDS YP_002037680.1 194396761 6480302 933104..933958 1 NC_011072.1 identified by match to protein family HMM PF03747; hydrolase 933958 6480302 SPG_0970 Streptococcus pneumoniae G54 hydrolase YP_002037680.1 933104 D 512566 CDS YP_002037681.1 194398068 6479880 934070..934954 1 NC_011072.1 identified by match to protein family HMM PF00781; match to protein family HMM TIGR00147; hypothetical protein 934954 6479880 SPG_0971 Streptococcus pneumoniae G54 hypothetical protein YP_002037681.1 934070 D 512566 CDS YP_002037682.1 194397715 6479400 935117..936244 1 NC_011072.1 identified by match to protein family HMM PF00128; match to protein family HMM PF02903; neopullulanase 936244 6479400 SPG_0972 Streptococcus pneumoniae G54 neopullulanase YP_002037682.1 935117 D 512566 CDS YP_002037683.1 194398127 6479969 936241..936567 1 NC_011072.1 contains potential frameshift; relaxase/mobilization nuclease domain 936567 6479969 SPG_0973 Streptococcus pneumoniae G54 relaxase/mobilization nuclease domain YP_002037683.1 936241 D 512566 CDS YP_002037684.1 194397656 6480650 936603..936803 1 NC_011072.1 contains potential frameshift; relaxase 936803 6480650 SPG_0974 Streptococcus pneumoniae G54 relaxase YP_002037684.1 936603 D 512566 CDS YP_002037685.1 194396657 6479069 936825..937529 1 NC_011072.1 identified by glimmer; putative; hypothetical protein 937529 6479069 SPG_0975 Streptococcus pneumoniae G54 hypothetical protein YP_002037685.1 936825 D 512566 CDS YP_002037686.1 194398338 6479687 complement(937570..938421) 1 NC_011072.1 identified by match to protein family HMM TIGR01716; Rgg/GadR/MutR family transcriptional activator 938421 6479687 SPG_0976 Streptococcus pneumoniae G54 Rgg/GadR/MutR family transcriptional activator YP_002037686.1 937570 R 512566 CDS YP_002037687.1 194397883 6480507 938678..939547 1 NC_011072.1 identified by glimmer; putative; hypothetical protein 939547 6480507 SPG_0977 Streptococcus pneumoniae G54 hypothetical protein YP_002037687.1 938678 D 512566 CDS YP_002037688.1 194397381 6480035 939534..940256 1 NC_011072.1 identified by glimmer; putative; hypothetical protein 940256 6480035 SPG_0978 Streptococcus pneumoniae G54 hypothetical protein YP_002037688.1 939534 D 512566 CDS YP_002037689.1 194398536 6479838 940581..940784 1 NC_011072.1 hypothetical protein 940784 6479838 SPG_0979 Streptococcus pneumoniae G54 hypothetical protein YP_002037689.1 940581 D 512566 CDS YP_002037690.1 194398519 6480002 940788..941882 1 NC_011072.1 identified by glimmer; putative; hypothetical protein 941882 6480002 SPG_0980 Streptococcus pneumoniae G54 hypothetical protein YP_002037690.1 940788 D 512566 CDS YP_002037691.1 194396736 6480795 941885..942556 1 NC_011072.1 identified by glimmer; putative; hypothetical protein 942556 6480795 SPG_0981 Streptococcus pneumoniae G54 hypothetical protein YP_002037691.1 941885 D 512566 CDS YP_002037692.1 194397285 6479701 942558..943586 1 NC_011072.1 identified by match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF02719; match to protein family HMM PF07993; match to protein family HMM TIGR01179; UDP-glucose 4-epimerase 943586 6479701 SPG_0982 Streptococcus pneumoniae G54 UDP-glucose 4-epimerase YP_002037692.1 942558 D 512566 CDS YP_002037693.1 194398195 6479367 943610..944854 1 NC_011072.1 identified by glimmer; putative; hypothetical protein 944854 6479367 SPG_0983 Streptococcus pneumoniae G54 hypothetical protein YP_002037693.1 943610 D 512566 CDS YP_002037694.1 194396651 6480629 944856..945263 1 NC_011072.1 ABC transporter permease 945263 6480629 SPG_0984 Streptococcus pneumoniae G54 ABC transporter permease YP_002037694.1 944856 D 512566 CDS YP_002037695.1 194397030 6479928 945273..946067 1 NC_011072.1 ABC transporter permease 946067 6479928 SPG_0985 Streptococcus pneumoniae G54 ABC transporter permease YP_002037695.1 945273 D 512566 CDS YP_002037696.1 194397548 6479914 946747..946968 1 NC_011072.1 identified by match to protein family HMM PF01381; hypothetical protein 946968 6479914 SPG_0986 Streptococcus pneumoniae G54 hypothetical protein YP_002037696.1 946747 D 512566 CDS YP_002037697.1 194398495 6479242 947416..947610 1 NC_011072.1 degenarate transposase 947610 6479242 SPG_0987 Streptococcus pneumoniae G54 degenarate transposase YP_002037697.1 947416 D 512566 CDS YP_002037698.1 194396963 6480514 947874..949103 1 NC_011072.1 identified by match to protein family HMM PF01098; cell division protein FtsW 949103 6480514 SPG_0988 Streptococcus pneumoniae G54 cell division protein FtsW YP_002037698.1 947874 D 512566 CDS YP_002037699.1 194397283 6480017 949123..951819 1 NC_011072.1 catalyzes the formation of oxaloacetate from phosphoenolpyruvate; phosphoenolpyruvate carboxylase 951819 ppc 6480017 ppc Streptococcus pneumoniae G54 phosphoenolpyruvate carboxylase YP_002037699.1 949123 D 512566 CDS YP_002037700.1 194398719 6478866 952232..953236 1 NC_011072.1 identified by match to protein family HMM PF04392; hypothetical protein 953236 6478866 SPG_0990 Streptococcus pneumoniae G54 hypothetical protein YP_002037700.1 952232 D 512566 CDS YP_002037701.1 194398392 6479332 953305..954171 1 NC_011072.1 identified by match to protein family HMM PF02653; ABC transporter permease 954171 6479332 SPG_0991 Streptococcus pneumoniae G54 ABC transporter permease YP_002037701.1 953305 D 512566 CDS YP_002037702.1 194396699 6478803 954168..954926 1 NC_011072.1 identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 954926 6478803 SPG_0992 Streptococcus pneumoniae G54 ABC transporter ATP-binding protein YP_002037702.1 954168 D 512566 CDS YP_002037703.1 194397481 6479674 955016..956776 1 NC_011072.1 synthesizes RNA primers at the replication forks; DNA primase 956776 dnaG 6479674 dnaG Streptococcus pneumoniae G54 DNA primase YP_002037703.1 955016 D 512566 CDS YP_002037704.1 194397936 6480054 956779..957888 1 NC_011072.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; primary sigma factor of bacterium; RNA polymerase sigma factor RpoD 957888 rpoD 6480054 rpoD Streptococcus pneumoniae G54 RNA polymerase sigma factor RpoD YP_002037704.1 956779 D 512566 CDS YP_002037705.1 194398656 6478918 957902..958231 1 NC_011072.1 identified by match to protein family HMM PF01883; hypothetical protein 958231 6478918 SPG_0995 Streptococcus pneumoniae G54 hypothetical protein YP_002037705.1 957902 D 512566 CDS YP_002037706.1 194397370 6478922 958346..959389 1 NC_011072.1 identified by match to protein family HMM PF00534; group 1 family glycosyl transferase 959389 6478922 SPG_0996 Streptococcus pneumoniae G54 group 1 family glycosyl transferase YP_002037706.1 958346 D 512566 CDS YP_002037707.1 194396697 6480014 959405..960730 1 NC_011072.1 identified by match to protein family HMM PF00534; group 1 family glycosyl transferase 960730 6480014 SPG_0997 Streptococcus pneumoniae G54 group 1 family glycosyl transferase YP_002037707.1 959405 D 512566 CDS YP_002037708.1 194398256 6479841 960761..960937 1 NC_011072.1 identified by match to protein family HMM PF04024; hypothetical protein 960937 6479841 SPG_0998 Streptococcus pneumoniae G54 hypothetical protein YP_002037708.1 960761 D 512566 CDS YP_002037709.1 194397868 6478970 960996..961130 1 NC_011072.1 hypothetical protein 961130 6478970 SPG_0999 Streptococcus pneumoniae G54 hypothetical protein YP_002037709.1 960996 D 512566 CDS YP_002037710.1 194397798 6480599 961200..962504 1 NC_011072.1 essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication; GTPase ObgE 962504 obgE 6480599 obgE Streptococcus pneumoniae G54 GTPase ObgE YP_002037710.1 961200 D 512566 CDS YP_002037711.1 194397611 6479920 962514..962672 1 NC_011072.1 hypothetical protein 962672 6479920 SPG_1001 Streptococcus pneumoniae G54 hypothetical protein YP_002037711.1 962514 D 512566 CDS YP_002037712.1 194397134 6478931 963815..965074 1 NC_011072.1 adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active; UDP-N-acetylglucosamine 1-carboxyvinyltransferase 965074 murA1 6478931 murA1 Streptococcus pneumoniae G54 UDP-N-acetylglucosamine 1-carboxyvinyltransferase YP_002037712.1 963815 D 512566 CDS YP_002037713.1 194396890 6479663 965090..965641 1 NC_011072.1 identified by match to protein family HMM PF00583; GNAT family acetyltransferase 965641 6479663 SPG_1003 Streptococcus pneumoniae G54 GNAT family acetyltransferase YP_002037713.1 965090 D 512566 CDS YP_002037714.1 194398023 6479123 965634..966911 1 NC_011072.1 identified by match to protein family HMM PF00571; match to protein family HMM PF03061; match to protein family HMM PF07085; match to protein family HMM PF08279; hypothetical protein 966911 6479123 SPG_1004 Streptococcus pneumoniae G54 hypothetical protein YP_002037714.1 965634 D 512566 CDS YP_002037715.1 194397110 6478653 966927..967787 1 NC_011072.1 catalyzes the removal of N-terminal amino acids from peptides and arylamides; methionine aminopeptidase 967787 6478653 SPG_1005 Streptococcus pneumoniae G54 methionine aminopeptidase YP_002037715.1 966927 D 512566 CDS YP_002037716.1 194398258 6480630 968012..968566 1 NC_011072.1 degenarate transposase 968566 6480630 SPG_1006 Streptococcus pneumoniae G54 degenarate transposase YP_002037716.1 968012 D 512566 CDS YP_002037717.1 194398021 6478972 968583..968972 1 NC_011072.1 identified by match to protein family HMM PF01609; degenarate transposase 968972 6478972 SPG_1007 Streptococcus pneumoniae G54 degenarate transposase YP_002037717.1 968583 D 512566 CDS YP_002037718.1 194397544 6479335 969164..971455 1 NC_011072.1 identified by match to protein family HMM PF00580; match to protein family HMM TIGR01073; ATP-dependent DNA helicase PcrA 971455 pcrA 6479335 pcrA Streptococcus pneumoniae G54 ATP-dependent DNA helicase PcrA YP_002037718.1 969164 D 512566 CDS YP_002037719.1 194397499 6479564 971498..972178 1 NC_011072.1 Involved in DNA double-strand break repair and recombination. Promotes the annealing of complementary single-stranded DNA and by simulation of RAD51 recombinase; DNA repair protein RadC 972178 radC 6479564 radC Streptococcus pneumoniae G54 DNA repair protein RadC YP_002037719.1 971498 D 512566 CDS YP_002037720.1 194397369 6478847 complement(972175..972864) 1 NC_011072.1 identified by match to protein family HMM PF00117; match to protein family HMM PF07722; glutamine amidotransferase 972864 6478847 SPG_1009 Streptococcus pneumoniae G54 glutamine amidotransferase YP_002037720.1 972175 R 512566 CDS YP_002037721.1 194398509 6480013 complement(972882..973523) 1 NC_011072.1 modulates transcription in response to the NADH/NAD(+) redox state; redox-sensing transcriptional repressor Rex 973523 6480013 SPG_1011 Streptococcus pneumoniae G54 redox-sensing transcriptional repressor Rex YP_002037721.1 972882 R 512566 CDS YP_002037722.1 194396716 6480591 complement(973606..973821) 1 NC_011072.1 hypothetical protein 973821 6480591 SPG_1012 Streptococcus pneumoniae G54 hypothetical protein YP_002037722.1 973606 R 512566 CDS YP_002037723.1 194396727 6480411 complement(973829..974176) 1 NC_011072.1 identified by match to protein family HMM PF08866; hypothetical protein 974176 6480411 SPG_1013 Streptococcus pneumoniae G54 hypothetical protein YP_002037723.1 973829 R 512566 CDS YP_002037724.1 194397239 6479855 complement(974181..975296) 1 NC_011072.1 identified by match to protein family HMM PF00266; class V aminotransferase 975296 6479855 SPG_1014 Streptococcus pneumoniae G54 class V aminotransferase YP_002037724.1 974181 R 512566 CDS YP_002037725.1 194398224 6480323 complement(975306..976265) 1 NC_011072.1 catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP; ribose-phosphate pyrophosphokinase 976265 prs2 6480323 prs2 Streptococcus pneumoniae G54 ribose-phosphate pyrophosphokinase YP_002037725.1 975306 R 512566 CDS YP_002037726.1 194398703 6479612 complement(976378..976947) 1 NC_011072.1 identified by match to protein family HMM PF01928; adenylate cyclase 976947 6479612 SPG_1016 Streptococcus pneumoniae G54 adenylate cyclase YP_002037726.1 976378 R 512566 CDS YP_002037727.1 194397029 6479442 977075..977746 1 NC_011072.1 identified by match to protein family HMM PF04607; pyrophosphokinase family protein 977746 6479442 SPG_1017 Streptococcus pneumoniae G54 pyrophosphokinase family protein YP_002037727.1 977075 D 512566 CDS YP_002037728.1 194397689 6480792 977730..978548 1 NC_011072.1 catalyzes the phosphorylation of NAD to NADP; inorganic polyphosphate/ATP-NAD kinase 978548 ppnK 6480792 ppnK Streptococcus pneumoniae G54 inorganic polyphosphate/ATP-NAD kinase YP_002037728.1 977730 D 512566 CDS YP_002037729.1 194398218 6479256 978545..979441 1 NC_011072.1 identified by match to protein family HMM PF00849; match to protein family HMM TIGR00005; RluD subfamily ribosomal large subunit pseudouridine synthase 979441 6479256 SPG_1019 Streptococcus pneumoniae G54 RluD subfamily ribosomal large subunit pseudouridine synthase YP_002037729.1 978545 D 512566 CDS YP_002037730.1 194397458 6479521 979485..980459 1 NC_011072.1 in Salmonella this enzyme is required for ethanolamine catabolism; has higher affinity for CoA than Pta; phosphotransacetylase 980459 eutD 6479521 eutD Streptococcus pneumoniae G54 phosphotransacetylase YP_002037730.1 979485 D 512566 CDS YP_002037731.1 194398532 6479814 complement(980859..981158) 1 NC_011072.1 identified by match to protein family HMM PF02575; match to protein family HMM TIGR00103; hypothetical protein 981158 6479814 SPG_1021 Streptococcus pneumoniae G54 hypothetical protein YP_002037731.1 980859 R 512566 CDS YP_002037732.1 194396858 6480283 981560..982258 1 NC_011072.1 identified by match to protein family HMM PF06912; hypothetical protein 982258 6480283 SPG_1022 Streptococcus pneumoniae G54 hypothetical protein YP_002037732.1 981560 D 512566 CDS YP_002037733.1 194397281 6479137 982570..982761 1 NC_011072.1 identified by match to protein family HMM PF00829; match to protein family HMM TIGR00061; 50S ribosomal protein L21 982761 rplU 6479137 rplU Streptococcus pneumoniae G54 50S ribosomal protein L21 YP_002037733.1 982570 D 512566 CDS YP_002037734.1 194397744 6478864 982777..983121 1 NC_011072.1 identified by match to protein family HMM PF04327; hypothetical protein 983121 6478864 SPG_1024 Streptococcus pneumoniae G54 hypothetical protein YP_002037734.1 982777 D 512566 CDS YP_002037735.1 194397923 6480428 983138..983431 1 NC_011072.1 involved in the peptidyltransferase reaction during translation; 50S ribosomal protein L27 983431 rpmA 6480428 rpmA Streptococcus pneumoniae G54 50S ribosomal protein L27 YP_002037735.1 983138 D 512566 CDS YP_002037736.1 194398389 6479296 complement(983636..983842) 1 NC_011072.1 hypothetical protein 983842 6479296 SPG_1026 Streptococcus pneumoniae G54 hypothetical protein YP_002037736.1 983636 R 512566 CDS YP_002037737.1 194398718 6478841 complement(983814..983939) 1 NC_011072.1 hypothetical protein 983939 6478841 SPG_1027 Streptococcus pneumoniae G54 hypothetical protein YP_002037737.1 983814 R 512566 CDS YP_002037738.1 194398283 6479331 984277..985194 1 NC_011072.1 catalyzes the formation of FMN from riboflavin and the formation of FAD from FMN; in Bacillus the ribC gene has both flavokinase and FAD synthetase activities; bifunctional riboflavin kinase/FMN adenylyltransferase 985194 mreA 6479331 mreA Streptococcus pneumoniae G54 bifunctional riboflavin kinase/FMN adenylyltransferase YP_002037738.1 984277 D 512566 CDS YP_002037739.1 194398246 6479406 complement(985287..986135) 1 NC_011072.1 identified by match to protein family HMM PF02588; hypothetical protein 986135 6479406 SPG_1029 Streptococcus pneumoniae G54 hypothetical protein YP_002037739.1 985287 R 512566 CDS YP_002037740.1 194398368 6479500 986277..987116 1 NC_011072.1 identified by glimmer; putative; hypothetical protein 987116 6479500 SPG_1030 Streptococcus pneumoniae G54 hypothetical protein YP_002037740.1 986277 D 512566 CDS YP_002037741.1 194397873 6479601 987222..987497 1 NC_011072.1 identified by match to protein family HMM PF00216; DNA-binding protein HU 987497 hup 6479601 hup Streptococcus pneumoniae G54 DNA-binding protein HU YP_002037741.1 987222 D 512566 CDS YP_002037742.1 194397700 6480486 987922..989823 1 NC_011072.1 identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 989823 6480486 SPG_1032 Streptococcus pneumoniae G54 ABC transporter ATP-binding protein YP_002037742.1 987922 D 512566 CDS YP_002037743.1 194396678 6479130 989826..990689 1 NC_011072.1 identified by match to protein family HMM TIGR01716; transcriptional activator MutR 990689 6479130 SPG_1033 Streptococcus pneumoniae G54 transcriptional activator MutR YP_002037743.1 989826 D 512566 CDS YP_002037744.1 194398520 6479797 990769..991947 1 NC_011072.1 identified by match to protein family HMM PF07690; major facilitator family transporter 991947 6479797 SPG_1034 Streptococcus pneumoniae G54 major facilitator family transporter YP_002037744.1 990769 D 512566 CDS YP_002037745.1 194398076 6480652 992040..993998 1 NC_011072.1 this protein catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction; essential for DNA replication and repair of damaged DNA; similar to ligase LigB; NAD-dependent DNA ligase LigA 993998 ligA 6480652 ligA Streptococcus pneumoniae G54 NAD-dependent DNA ligase LigA YP_002037745.1 992040 D 512566 CDS YP_002037746.1 194396945 6479469 994110..996206 1 NC_011072.1 contains potential frameshift; identified by match to protein family HMM PF00128; match to protein family HMM PF02922; match to protein family HMM TIGR02104; thermostable pullulanase 996206 6479469 SPG_1036 Streptococcus pneumoniae G54 thermostable pullulanase YP_002037746.1 994110 D 512566 CDS YP_002037747.1 194397565 6479650 996262..996390 1 NC_011072.1 contains potential frameshift; thermostable pullulanase 996390 6479650 SPG_1037 Streptococcus pneumoniae G54 thermostable pullulanase YP_002037747.1 996262 D 512566 CDS YP_002037748.1 194397789 6479190 996935..998359 1 NC_011072.1 identified by match to protein family HMM PF00171; NADP-dependent glyceraldehyde-3-phosphate dehydrogenase 998359 6479190 SPG_1038 Streptococcus pneumoniae G54 NADP-dependent glyceraldehyde-3-phosphate dehydrogenase YP_002037748.1 996935 D 512566 CDS YP_002037749.1 194398655 6480080 998735..1000663 1 NC_011072.1 catalyzes the transfer of a segment of a 1,4-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain; glycogen branching enzyme 1000663 glgB 6480080 glgB Streptococcus pneumoniae G54 glycogen branching enzyme YP_002037749.1 998735 D 512566 CDS YP_002037750.1 194397203 6478921 1000653..1001795 1 NC_011072.1 catalyzes the formation of ADP-glucose and diphosphate from ATP and alpha-D-glucose 1-phosphate; glucose-1-phosphate adenylyltransferase 1001795 glgC 6478921 glgC Streptococcus pneumoniae G54 glucose-1-phosphate adenylyltransferase YP_002037750.1 1000653 D 512566 CDS YP_002037751.1 194396720 6480089 1001785..1002924 1 NC_011072.1 Spatafora,G.A. 1992 Inf.& Imm.; identified by match to protein family HMM PF00483; match to protein family HMM TIGR02092; glucose-1-phosphate adenylyltransferase subunit GlgD 1002924 glgD 6480089 glgD Streptococcus pneumoniae G54 glucose-1-phosphate adenylyltransferase subunit GlgD YP_002037751.1 1001785 D 512566 CDS YP_002037752.1 194398087 6480317 1002921..1004354 1 NC_011072.1 catalyzes the formation of alpha-1,4-glucan chains from ADP-glucose; glycogen synthase 1004354 glgA 6480317 glgA Streptococcus pneumoniae G54 glycogen synthase YP_002037752.1 1002921 D 512566 CDS YP_002037753.1 194397673 6478948 1004413..1004784 1 NC_011072.1 phosphoserine phosphatase 1004784 6478948 SPG_1043 Streptococcus pneumoniae G54 phosphoserine phosphatase YP_002037753.1 1004413 D 512566 CDS YP_002037754.1 194397567 6479607 1004900..1005058 1 NC_011072.1 hypothetical protein 1005058 6479607 SPG_1044 Streptococcus pneumoniae G54 hypothetical protein YP_002037754.1 1004900 D 512566 CDS YP_002037755.1 194398512 6479303 1005067..1006182 1 NC_011072.1 identified by match to protein family HMM PF02595; match to protein family HMM TIGR00045; glycerate kinase 1006182 6479303 SPG_1046 Streptococcus pneumoniae G54 glycerate kinase YP_002037755.1 1005067 D 512566 CDS YP_002037756.1 194397112 6480212 complement(1006179..1006625) 1 NC_011072.1 identified by match to protein family HMM PF07997; hypothetical protein 1006625 6480212 SPG_1045 Streptococcus pneumoniae G54 hypothetical protein YP_002037756.1 1006179 R 512566 CDS YP_002037757.1 194397910 6480472 1006789..1008093 1 NC_011072.1 enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis; phosphopyruvate hydratase 1008093 eno 6480472 eno Streptococcus pneumoniae G54 phosphopyruvate hydratase YP_002037757.1 1006789 D 512566 CDS YP_002037758.1 194397771 6479052 complement(1008231..1008677) 1 NC_011072.1 identified by match to protein family HMM PF00589; phage integrase family site-specific recombinase 1008677 6479052 SPG_1048 Streptococcus pneumoniae G54 phage integrase family site-specific recombinase YP_002037758.1 1008231 R 512566 CDS YP_002037759.1 194397444 6480026 complement(1009094..1009423) 1 NC_011072.1 identified by match to protein family HMM PF01710; IS630-Spn1 transposase 1009423 6480026 SPG_1049 Streptococcus pneumoniae G54 IS630-Spn1 transposase YP_002037759.1 1009094 R 512566 CDS YP_002037760.1 194397131 6480349 1009949..1013224 1 NC_011072.1 identified by match to protein family HMM TIGR02774; exonuclease RexB 1013224 rexB 6480349 rexB Streptococcus pneumoniae G54 exonuclease RexB YP_002037760.1 1009949 D 512566 CDS YP_002037761.1 194397993 6479678 1013221..1016871 1 NC_011072.1 identified by match to protein family HMM PF00580; match to protein family HMM TIGR02785; exonuclease RexA 1016871 rexA 6479678 rexA Streptococcus pneumoniae G54 exonuclease RexA YP_002037761.1 1013221 D 512566 CDS YP_002037762.1 194397916 6478773 1017266..1018444 1 NC_011072.1 hypothetical protein 1018444 6478773 SPG_1052 Streptococcus pneumoniae G54 hypothetical protein YP_002037762.1 1017266 D 512566 CDS YP_002037763.1 194398492 6478876 1018653..1024490 1 NC_011072.1 identified by match to protein family HMM PF00746; match to protein family HMM PF04650; match to protein family HMM PF07501; match to protein family HMM PF07580; match to protein family HMM PF07581; match to protein family HMM TIGR01167; match to protein family HMM TIGR01168; immunoglobulin A1 protease 1024490 igA 6478876 igA Streptococcus pneumoniae G54 immunoglobulin A1 protease YP_002037763.1 1018653 D 512566 CDS YP_002037764.1 194396680 6480369 1024534..1029771 1 NC_011072.1 identified by match to protein family HMM PF00746; match to protein family HMM PF07501; match to protein family HMM PF07580; match to protein family HMM TIGR01167; zinc metalloprotease ZmpD 1029771 zmpD 6480369 zmpD Streptococcus pneumoniae G54 zinc metalloprotease ZmpD YP_002037764.1 1024534 D 512566 CDS YP_002037765.1 194397273 6479637 1029938..1031284 1 NC_011072.1 identified by match to protein family HMM PF01609; IS1380-Spn1 transposase 1031284 6479637 SPG_1055 Streptococcus pneumoniae G54 IS1380-Spn1 transposase YP_002037765.1 1029938 D 512566 CDS YP_002037766.1 194398237 6479547 complement(1031470..1031631) 1 NC_011072.1 identified by glimmer; putative; hypothetical protein 1031631 6479547 SPG_1056 Streptococcus pneumoniae G54 hypothetical protein YP_002037766.1 1031470 R 512566 CDS YP_002037767.1 194398607 6478872 1031699..1032550 1 NC_011072.1 essential GTPase; functions in ribosome assembly; binds a unique part of the 23S rRNA; interacts with ribosomal protein L25(Ctc); ribosomal biogenesis GTPase 1032550 rbgA 6478872 rbgA Streptococcus pneumoniae G54 ribosomal biogenesis GTPase YP_002037767.1 1031699 D 512566 CDS YP_002037768.1 194396938 6479193 1032537..1033316 1 NC_011072.1 RNH2; RNase HII; binds manganese; endonuclease which specifically degrades the RNA of RNA-DNA hybrids; ribonuclease HII 1033316 rnhB 6479193 rnhB Streptococcus pneumoniae G54 ribonuclease HII YP_002037768.1 1032537 D 512566 CDS YP_002037769.1 194398647 6480312 1033332..1034882 1 NC_011072.1 identified by match to protein family HMM PF00654; match to protein family HMM PF02080; voltage-gated chloride channel family protein 1034882 6480312 SPG_1059 Streptococcus pneumoniae G54 voltage-gated chloride channel family protein YP_002037769.1 1033332 D 512566 CDS YP_002037770.1 194398032 6479503 1035466..1036536 1 NC_011072.1 site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; cell division protein FtsK may regulate the XerS; site-specific tyrosine recombinase XerS 1036536 xerS 6479503 xerS Streptococcus pneumoniae G54 site-specific tyrosine recombinase XerS YP_002037770.1 1035466 D 512566 CDS YP_002037771.1 194397426 6479064 complement(1036603..1037592) 1 NC_011072.1 Morris,T.W. 1994 Journ.Biol.Chem.; identified by match to protein family HMM PF03099; match to protein family HMM TIGR00545; lipoate protein ligase A 1037592 lplA 6479064 lplA Streptococcus pneumoniae G54 lipoate protein ligase A YP_002037771.1 1036603 R 512566 CDS YP_002037772.1 194398618 6480186 complement(1037656..1039359) 1 NC_011072.1 identified by match to protein family HMM PF00070; match to protein family HMM PF00364; match to protein family HMM PF01134; match to protein family HMM PF02852; match to protein family HMM PF03486; match to protein family HMM PF07992; match to protein family HMM TIGR01350; dihydrolipoyl dehydrogenase 1039359 lpdA 6480186 lpdA Streptococcus pneumoniae G54 dihydrolipoyl dehydrogenase YP_002037772.1 1037656 R 512566 CDS YP_002037773.1 194397054 6479279 complement(1039405..1040448) 1 NC_011072.1 unlike PdhC proteins from other organisms, some Mycoplasma lack an N-terminal lipoyl domain; in Mycoplasma hyopneumonia the PdhD proteins contains the lipoyl domain; dihydrolipoamide acetyltransferase 1040448 6479279 SPG_1063 Streptococcus pneumoniae G54 dihydrolipoamide acetyltransferase YP_002037773.1 1039405 R 512566 CDS YP_002037774.1 194397679 6479667 complement(1040666..1041658) 1 NC_011072.1 identified by match to protein family HMM PF02779; match to protein family HMM PF02780; acetoin dehydrogenase E1 component subunit beta 1041658 6479667 SPG_1064 Streptococcus pneumoniae G54 acetoin dehydrogenase E1 component subunit beta YP_002037774.1 1040666 R 512566 CDS YP_002037775.1 194398360 6478839 complement(1041674..1042642) 1 NC_011072.1 identified by match to protein family HMM PF00676; TPP-dependent acetoin dehydrogenase subunit alpha 1042642 6478839 SPG_1065 Streptococcus pneumoniae G54 TPP-dependent acetoin dehydrogenase subunit alpha YP_002037775.1 1041674 R 512566 CDS YP_002037776.1 194396831 6480757 complement(1042796..1044157) 1 NC_011072.1 identified by match to protein family HMM PF01554; match to protein family HMM TIGR00797; MATE efflux family protein 1044157 6480757 SPG_1066 Streptococcus pneumoniae G54 MATE efflux family protein YP_002037776.1 1042796 R 512566 CDS YP_002037777.1 194397406 6480563 complement(1044442..1045710) 1 NC_011072.1 catalyzes the formation of N-carbamoyl-L-aspartate from (S)-dihydroorotate in pyrimidine biosynthesis; dihydroorotase 1045710 pyrC 6480563 pyrC Streptococcus pneumoniae G54 dihydroorotase YP_002037777.1 1044442 R 512566 CDS YP_002037778.1 194397879 6480061 complement(1045723..1046187) 1 NC_011072.1 identified by match to protein family HMM PF00293; mutator mutT protein 1046187 mutX 6480061 mutX Streptococcus pneumoniae G54 mutator mutT protein YP_002037778.1 1045723 R 512566 CDS YP_002037779.1 194397361 6480239 complement(1046197..1046850) 1 NC_011072.1 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine; uracil-DNA glycosylase 1046850 6480239 SPG_1069 Streptococcus pneumoniae G54 uracil-DNA glycosylase YP_002037779.1 1046197 R 512566 CDS YP_002037780.1 194397713 6480137 complement(1046986..1047588) 1 NC_011072.1 hypothetical protein 1047588 6480137 SPG_1070 Streptococcus pneumoniae G54 hypothetical protein YP_002037780.1 1046986 R 512566 CDS YP_002037781.1 194398309 6479967 complement(1047646..1048359) 1 NC_011072.1 identified by match to protein family HMM PF00702; match to protein family HMM TIGR01549; match to protein family HMM TIGR02254; haloacid dehalogenase-like hydrolase 1048359 6479967 SPG_1071 Streptococcus pneumoniae G54 haloacid dehalogenase-like hydrolase YP_002037781.1 1047646 R 512566 CDS YP_002037782.1 194397042 6479166 complement(1048756..1048986) 1 NC_011072.1 identified by match to protein family HMM PF03610; PTS system transporter subunit IIA 1048986 6479166 SPG_1072 Streptococcus pneumoniae G54 PTS system transporter subunit IIA YP_002037782.1 1048756 R 512566 CDS YP_002037783.1 194397660 6479992 complement(1049408..1051930) 1 NC_011072.1 Adamou JE, Infect Immun. 2001 Feb;69(2):949-58. c; identified by match to protein family HMM PF04270; match to protein family HMM TIGR01363; histidine triad protein PhtA/B 1051930 phtA/B 6479992 phtA/B Streptococcus pneumoniae G54 histidine triad protein PhtA/B YP_002037783.1 1049408 R 512566 CDS YP_002037784.1 194398036 6479576 complement(1052183..1053916) 1 NC_011072.1 identified by match to protein family HMM PF00391; match to protein family HMM PF02896; match to protein family HMM PF05524; match to protein family HMM TIGR01417; phosphoenolpyruvate-protein phosphotransferase 1053916 ptsI 6479576 ptsI Streptococcus pneumoniae G54 phosphoenolpyruvate-protein phosphotransferase YP_002037784.1 1052183 R 512566 CDS YP_002037785.1 194398596 6478930 complement(1053922..1054185) 1 NC_011072.1 identified by match to protein family HMM PF00381; match to protein family HMM TIGR01003; phosphocarrier protein HPr 1054185 ptsH 6478930 ptsH Streptococcus pneumoniae G54 phosphocarrier protein HPr YP_002037785.1 1053922 R 512566 CDS YP_002037786.1 194398292 6479324 1054536..1054754 1 NC_011072.1 identified by match to protein family HMM PF00462; match to protein family HMM TIGR02194; NrdH-redoxin 1054754 nrdH 6479324 nrdH Streptococcus pneumoniae G54 NrdH-redoxin YP_002037786.1 1054536 D 512566 CDS YP_002037787.1 194398211 6478973 1054835..1056994 1 NC_011072.1 Catalyzes the rate-limiting step in dNTP synthesis; ribonucleotide-diphosphate reductase subunit alpha 1056994 nrdA 6478973 nrdA Streptococcus pneumoniae G54 ribonucleotide-diphosphate reductase subunit alpha YP_002037787.1 1054835 D 512566 CDS YP_002037788.1 194397329 6478889 1057182..1058144 1 NC_011072.1 B2 or R2 protein; type 1b enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdE; ribonucleotide-diphosphate reductase subunit beta 1058144 nrdF 6478889 nrdF Streptococcus pneumoniae G54 ribonucleotide-diphosphate reductase subunit beta YP_002037788.1 1057182 D 512566 CDS YP_002037789.1 194398465 6479925 1058326..1059087 1 NC_011072.1 identified by match to protein family HMM PF00455; match to protein family HMM PF08220; match to protein family HMM PF08279; lactose phosphotransferase system repressor 1059087 6479925 SPG_1079 Streptococcus pneumoniae G54 lactose phosphotransferase system repressor YP_002037789.1 1058326 D 512566 CDS YP_002037790.1 194396998 6479934 complement(1059366..1059545) 1 NC_011072.1 hypothetical protein 1059545 6479934 SPG_1080 Streptococcus pneumoniae G54 hypothetical protein YP_002037790.1 1059366 R 512566 CDS YP_002037791.1 194397463 6479739 complement(1059668..1061074) 1 NC_011072.1 catalyzes the formation of 6-phospho-galactose from a 6-phospho-beta-galactoside; 6-phospho-beta-galactosidase 1061074 lacG 6479739 lacG Streptococcus pneumoniae G54 6-phospho-beta-galactosidase YP_002037791.1 1059668 R 512566 CDS YP_002037792.1 194398227 6479996 complement(1061289..1062980) 1 NC_011072.1 identified by match to protein family HMM PF02302; match to protein family HMM PF02378; match to protein family HMM TIGR00394; match to protein family HMM TIGR00410; match to protein family HMM TIGR00853; PTS system transporter subunit IIBC 1062980 6479996 SPG_1082 Streptococcus pneumoniae G54 PTS system transporter subunit IIBC YP_002037792.1 1061289 R 512566 CDS YP_002037793.1 194398361 6478769 complement(1062980..1063297) 1 NC_011072.1 identified by match to protein family HMM PF02255; match to protein family HMM TIGR00823; PTS system transporter subunit IIA 1063297 6478769 SPG_1083 Streptococcus pneumoniae G54 PTS system transporter subunit IIA YP_002037793.1 1062980 R 512566 CDS YP_002037794.1 194398559 6480109 complement(1063333..1064169) 1 NC_011072.1 identified by match to protein family HMM PF00874; match to protein family HMM PF03123; transcription antiterminator LacT 1064169 6480109 SPG_1084 Streptococcus pneumoniae G54 transcription antiterminator LacT YP_002037794.1 1063333 R 512566 CDS YP_002037795.1 194397953 6479088 complement(1064403..1065383) 1 NC_011072.1 catalyzes the reversible reaction of dihydroxyacetone phosphate with glyceraldehyde 3-phosphate to produce tagatose 1,6-bisphosphate; in Streptococcus pyogenes there are two paralogs of tagatose-bisphosphate aldolase, encoded by lacD1 and lacD2; expression of lacD1 is highly regulated by environmental conditions while lacD2 specializes in an efficient utilization of carbohydrate sources; tagatose 1,6-diphosphate aldolase 1065383 lacD 6479088 lacD Streptococcus pneumoniae G54 tagatose 1,6-diphosphate aldolase YP_002037795.1 1064403 R 512566 CDS YP_002037796.1 194397495 6478686 complement(1065385..1066314) 1 NC_011072.1 catalyzes the formation of tagatose 1,6-bisphosphate from tagatose 6-phosphate and ATP; tagatose-6-phosphate kinase 1066314 lacC 6478686 lacC Streptococcus pneumoniae G54 tagatose-6-phosphate kinase YP_002037796.1 1065385 R 512566 CDS YP_002037797.1 194397017 6480347 complement(1066325..1066840) 1 NC_011072.1 catalyzes the interconversion of galactose 6-phosphate to tagatose 6-phosphate; galactose-6-phosphate isomerase subunit LacB 1066840 lacB 6480347 lacB Streptococcus pneumoniae G54 galactose-6-phosphate isomerase subunit LacB YP_002037797.1 1066325 R 512566 CDS YP_002037798.1 194398390 6480700 complement(1066871..1067296) 1 NC_011072.1 catalyzes the interconversion of galactose 6-phosphate to tagatose 6-phosphate; tagatose pathway for galactose utilization; galactose-6-phosphate isomerase subunit LacA 1067296 lacA 6480700 lacA Streptococcus pneumoniae G54 galactose-6-phosphate isomerase subunit LacA YP_002037798.1 1066871 R 512566 CDS YP_002037799.1 194396725 6478842 complement(1067453..1067797) 1 NC_011072.1 identified by glimmer; putative; hypothetical protein 1067797 6478842 SPG_1089 Streptococcus pneumoniae G54 hypothetical protein YP_002037799.1 1067453 R 512566 CDS YP_002037800.1 194397200 6480108 complement(1068007..1068354) 1 NC_011072.1 transposase 1068354 6480108 SPG_1090 Streptococcus pneumoniae G54 transposase YP_002037800.1 1068007 R 512566 CDS YP_002037801.1 194397918 6480770 complement(1068371..1068769) 1 NC_011072.1 transposase 1068769 6480770 SPG_1091 Streptococcus pneumoniae G54 transposase YP_002037801.1 1068371 R 512566 CDS YP_002037802.1 194396876 6479175 complement(1068777..1069079) 1 NC_011072.1 PTS system transporter subunit IIB 1069079 6479175 SPG_1092 Streptococcus pneumoniae G54 PTS system transporter subunit IIB YP_002037802.1 1068777 R 512566 CDS YP_002037803.1 194397344 6479328 complement(1069117..1069503) 1 NC_011072.1 PTS system transporter subunit IIA 1069503 6479328 SPG_1093 Streptococcus pneumoniae G54 PTS system transporter subunit IIA YP_002037803.1 1069117 R 512566 CDS YP_002037804.1 194398543 6480437 complement(1070140..1071963) 1 NC_011072.1 binds to the ribosome on the universally-conserved alpha-sarcin loop; GTP-binding protein LepA 1071963 6480437 SPG_1094 Streptococcus pneumoniae G54 GTP-binding protein LepA YP_002037804.1 1070140 R 512566 CDS YP_002037805.1 194397516 6480623 complement(1072042..1072770) 1 NC_011072.1 identified by match to protein family HMM PF00149; Ser/Thr protein phosphatase family protein 1072770 6480623 SPG_1095 Streptococcus pneumoniae G54 Ser/Thr protein phosphatase family protein YP_002037805.1 1072042 R 512566 CDS YP_002037806.1 194398186 6479402 complement(1072772..1074439) 1 NC_011072.1 identified by match to protein family HMM PF02463; match to protein family HMM TIGR00634; DNA repair protein RecN 1074439 recN 6479402 recN Streptococcus pneumoniae G54 DNA repair protein RecN YP_002037806.1 1072772 R 512566 CDS YP_002037807.1 194397834 6480290 complement(1074446..1074877) 1 NC_011072.1 identified by match to protein family HMM PF01316; match to protein family HMM PF02863; transcriptional repressor 1074877 6480290 SPG_1097 Streptococcus pneumoniae G54 transcriptional repressor YP_002037807.1 1074446 R 512566 CDS YP_002037808.1 194398471 6480669 complement(1074870..1075685) 1 NC_011072.1 identified by match to protein family HMM PF01479; match to protein family HMM PF01728; match to protein family HMM TIGR00478; hemolysin A 1075685 6480669 SPG_1098 Streptococcus pneumoniae G54 hemolysin A YP_002037808.1 1074870 R 512566 CDS YP_002037809.1 194396799 6480678 complement(1075678..1076553) 1 NC_011072.1 identified by match to protein family HMM PF00348; geranyltranstransferase 1076553 ispA 6480678 ispA Streptococcus pneumoniae G54 geranyltranstransferase YP_002037809.1 1075678 R 512566 CDS YP_002037810.1 194397220 6478873 complement(1076550..1076762) 1 NC_011072.1 catalyzes the bidirectional exonucleolytic cleavage of DNA; exodeoxyribonuclease VII small subunit 1076762 xseB 6478873 xseB Streptococcus pneumoniae G54 exodeoxyribonuclease VII small subunit YP_002037810.1 1076550 R 512566 CDS YP_002037811.1 194397974 6480522 complement(1076740..1078080) 1 NC_011072.1 bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides; exodeoxyribonuclease VII large subunit 1078080 xseA 6480522 xseA Streptococcus pneumoniae G54 exodeoxyribonuclease VII large subunit YP_002037811.1 1076740 R 512566 CDS YP_002037812.1 194397133 6479473 complement(1078208..1078846) 1 NC_011072.1 functions in pyrimidine salvage; pyrimidine ribonucleoside kinase; phosphorylates nucleosides or dinucleosides to make UMP or CMP using ATP or GTP as the donor; uridine kinase 1078846 udk 6479473 udk Streptococcus pneumoniae G54 uridine kinase YP_002037812.1 1078208 R 512566 CDS YP_002037813.1 194397615 6480556 complement(1078954..1079256) 1 NC_011072.1 hypothetical protein 1079256 6480556 SPG_1103 Streptococcus pneumoniae G54 hypothetical protein YP_002037813.1 1078954 R 512566 CDS YP_002037814.1 194398540 6478830 complement(1079497..1080375) 1 NC_011072.1 catalyzes isomerization of specific uridines in RNA to pseudouridine; responsible for residues in T loops of many tRNAs; tRNA pseudouridine synthase B 1080375 truB 6478830 truB Streptococcus pneumoniae G54 tRNA pseudouridine synthase B YP_002037814.1 1079497 R 512566 CDS YP_002037815.1 194398060 6480539 complement(1080476..1083661) 1 NC_011072.1 hypothetical protein 1083661 6480539 SPG_1105 Streptococcus pneumoniae G54 hypothetical protein YP_002037815.1 1080476 R 512566 CDS YP_002037816.1 194397907 6479036 complement(1083673..1084947) 1 NC_011072.1 hypothetical protein 1084947 6479036 SPG_1106 Streptococcus pneumoniae G54 hypothetical protein YP_002037816.1 1083673 R 512566 CDS YP_002037817.1 194397399 6478896 complement(1085043..1086158) 1 NC_011072.1 identified by match to protein family HMM PF01041; match to protein family HMM PF01053; match to protein family HMM PF01212; match to protein family HMM TIGR01326; O-acetylhomoserine sulfhydrylase 1086158 6478896 SPG_1107 Streptococcus pneumoniae G54 O-acetylhomoserine sulfhydrylase YP_002037817.1 1085043 R 512566 CDS YP_002037818.1 194397617 6480292 complement(1086180..1086302) 1 NC_011072.1 hypothetical protein 1086302 6480292 SPG_1108 Streptococcus pneumoniae G54 hypothetical protein YP_002037818.1 1086180 R 512566 CDS YP_002037819.1 194397118 6478728 complement(1086450..1087247) 1 NC_011072.1 identified by match to protein family HMM PF01226; FNT family transporter 1087247 6478728 SPG_1109 Streptococcus pneumoniae G54 FNT family transporter YP_002037819.1 1086450 R 512566 CDS YP_002037820.1 194398280 6479718 complement(1087491..1088234) 1 NC_011072.1 identified by match to protein family HMM PF04203; match to protein family HMM TIGR01076; sortase family protein 1088234 6479718 SPG_1110 Streptococcus pneumoniae G54 sortase family protein YP_002037820.1 1087491 R 512566 CDS YP_002037821.1 194397830 6479317 complement(1088234..1090702) 1 NC_011072.1 negatively supercoils closed circular double-stranded DNA; DNA gyrase subunit A 1090702 gyrA 6479317 gyrA Streptococcus pneumoniae G54 DNA gyrase subunit A YP_002037821.1 1088234 R 512566 CDS YP_002037822.1 194397973 6480459 1090896..1091882 1 NC_011072.1 Converts (S)-lactate and NAD(+) to pyruvate and NADH; L-lactate dehydrogenase 1091882 ldh 6480459 ldh Streptococcus pneumoniae G54 L-lactate dehydrogenase YP_002037822.1 1090896 D 512566 CDS YP_002037823.1 194398339 6478732 complement(1092171..1092914) 1 NC_011072.1 identified by match to protein family HMM PF00520; match to protein family HMM PF07885; transporter, cation channel family 1092914 6478732 SPG_1113 Streptococcus pneumoniae G54 transporter, cation channel family YP_002037823.1 1092171 R 512566 CDS YP_002037824.1 194397028 6480508 complement(1092961..1093215) 1 NC_011072.1 identified by glimmer; putative; hypothetical protein 1093215 6480508 SPG_1114 Streptococcus pneumoniae G54 hypothetical protein YP_002037824.1 1092961 R 512566 CDS YP_002037825.1 194397339 6479665 complement(1093217..1093459) 1 NC_011072.1 hypothetical protein 1093459 6479665 SPG_1115 Streptococcus pneumoniae G54 hypothetical protein YP_002037825.1 1093217 R 512566 CDS YP_002037826.1 194397665 6480707 complement(1093550..1094359) 1 NC_011072.1 identified by match to protein family HMM PF00753; VicX protein 1094359 6480707 SPG_1116 Streptococcus pneumoniae G54 VicX protein YP_002037826.1 1093550 R 512566 CDS YP_002037827.1 194398370 6479595 complement(1094361..1095710) 1 NC_011072.1 identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF00989; match to protein family HMM PF02518; match to protein family HMM TIGR00229; histidine kinase 1095710 micB 6479595 micB Streptococcus pneumoniae G54 histidine kinase YP_002037827.1 1094361 R 512566 CDS YP_002037828.1 194397986 6479167 complement(1095703..1096407) 1 NC_011072.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00486; response regulator 1096407 micA 6479167 micA Streptococcus pneumoniae G54 response regulator YP_002037828.1 1095703 R 512566 CDS YP_002037829.1 194397550 6479603 complement(1096463..1097638) 1 NC_011072.1 identified by match to protein family HMM PF00633; match to protein family HMM PF00730; match to protein family HMM TIGR01084; A/G-specific adenine glycosylase 1097638 mutY 6479603 mutY Streptococcus pneumoniae G54 A/G-specific adenine glycosylase YP_002037829.1 1096463 R 512566 CDS YP_002037830.1 194397319 6479244 complement(1097966..1099636) 1 NC_011072.1 catalyzes the formation of 10-formyltetrahydrofolate from formate and tetrahydrofolate; formate--tetrahydrofolate ligase 1099636 fhs 6479244 fhs Streptococcus pneumoniae G54 formate--tetrahydrofolate ligase YP_002037830.1 1097966 R 512566 CDS YP_002037831.1 194396906 6480425 1099866..1100555 1 NC_011072.1 identified by match to protein family HMM PF04127; match to protein family HMM TIGR02114; phosphopantothenate--cysteine ligase 1100555 coaB 6480425 coaB Streptococcus pneumoniae G54 phosphopantothenate--cysteine ligase YP_002037831.1 1099866 D 512566 CDS YP_002037832.1 194398329 6480303 1100567..1101118 1 NC_011072.1 decarboxylates 4-phosphopantothenoylcysteine to form 4'-phosphopantotheine.; phosphopantothenoylcysteine decarboxylase 1101118 coaC 6480303 coaC Streptococcus pneumoniae G54 phosphopantothenoylcysteine decarboxylase YP_002037832.1 1100567 D 512566 CDS YP_002037833.1 194397787 6479290 1101102..1101665 1 NC_011072.1 hypothetical protein 1101665 6479290 SPG_1123 Streptococcus pneumoniae G54 hypothetical protein YP_002037833.1 1101102 D 512566 CDS YP_002037834.1 194397574 6480078 1101948..1102475 1 NC_011072.1 hypothetical protein 1102475 6480078 SPG_1124 Streptococcus pneumoniae G54 hypothetical protein YP_002037834.1 1101948 D 512566 CDS YP_002037835.1 194398685 6479270 1102487..1103002 1 NC_011072.1 identified by match to protein family HMM PF02829; match to protein family HMM PF08279; transcriptional regulator 1103002 6479270 SPG_1126 Streptococcus pneumoniae G54 transcriptional regulator YP_002037835.1 1102487 D 512566 CDS YP_002037836.1 194396974 6478877 complement(1102999..1103466) 1 NC_011072.1 identified by match to protein family HMM PF00293; mutT/nudix family protein 1103466 6478877 SPG_1125 Streptococcus pneumoniae G54 mutT/nudix family protein YP_002037836.1 1102999 R 512566 CDS YP_002037837.1 194398247 6480562 complement(1103540..1104028) 1 NC_011072.1 identified by match to protein family HMM PF00583; GNAT family acetyltransferase 1104028 6480562 SPG_1127 Streptococcus pneumoniae G54 GNAT family acetyltransferase YP_002037837.1 1103540 R 512566 CDS YP_002037838.1 194398416 6479045 complement(1103994..1104557) 1 NC_011072.1 GNAT family acetyltransferase 1104557 6479045 SPG_1128 Streptococcus pneumoniae G54 GNAT family acetyltransferase YP_002037838.1 1103994 R 512566 CDS YP_002037839.1 194396794 6480467 complement(1104567..1106555) 1 NC_011072.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion; excinuclease ABC subunit B 1106555 uvrB 6480467 uvrB Streptococcus pneumoniae G54 excinuclease ABC subunit B YP_002037839.1 1104567 R 512566 CDS YP_002037840.1 194397417 6479534 complement(1106632..1107585) 1 NC_011072.1 identified by match to protein family HMM PF02517; CAAX amino terminal protease family 1107585 6479534 SPG_1130 Streptococcus pneumoniae G54 CAAX amino terminal protease family YP_002037840.1 1106632 R 512566 CDS YP_002037841.1 194398103 6479830 1107758..1109923 1 NC_011072.1 identified by match to protein family HMM PF00497; match to protein family HMM PF00528; match to protein family HMM TIGR01726; ABC transporter amino acid-binding protein/permease 1109923 glnP 6479830 glnP Streptococcus pneumoniae G54 ABC transporter amino acid-binding protein/permease YP_002037841.1 1107758 D 512566 CDS YP_002037842.1 194397296 6479681 1109923..1110663 1 NC_011072.1 identified by match to protein family HMM PF00005; glutamine ABC transporter ATP-binding protein 1110663 glnQ 6479681 glnQ Streptococcus pneumoniae G54 glutamine ABC transporter ATP-binding protein YP_002037842.1 1109923 D 512566 CDS YP_002037843.1 194397874 6478710 1110812..1112299 1 NC_011072.1 catalyzes the formation of D-glucono-1,5-lactone 6-phosphate from D-glucose 6-phosphate; glucose-6-phosphate 1-dehydrogenase 1112299 zwf 6478710 zwf Streptococcus pneumoniae G54 glucose-6-phosphate 1-dehydrogenase YP_002037843.1 1110812 D 512566 CDS YP_002037844.1 194398069 6480730 complement(1112345..1113622) 1 NC_011072.1 identified by match to protein family HMM PF00448; match to protein family HMM PF02881; match to protein family HMM TIGR00064; signal recognition particle-docking protein FtsY 1113622 ftsY 6480730 ftsY Streptococcus pneumoniae G54 signal recognition particle-docking protein FtsY YP_002037844.1 1112345 R 512566 CDS YP_002037845.1 194398568 6479162 complement(1113626..1114444) 1 NC_011072.1 identified by match to protein family HMM PF00702; match to protein family HMM PF05116; match to protein family HMM PF08282; match to protein family HMM TIGR00099; match to protein family HMM TIGR01484; Cof family protein 1114444 6479162 SPG_1135 Streptococcus pneumoniae G54 Cof family protein YP_002037845.1 1113626 R 512566 CDS YP_002037846.1 194397456 6479283 complement(1114444..1115238) 1 NC_011072.1 identified by match to protein family HMM PF00702; match to protein family HMM PF05116; match to protein family HMM PF08282; match to protein family HMM TIGR00099; match to protein family HMM TIGR01484; Cof family protein 1115238 6479283 SPG_1136 Streptococcus pneumoniae G54 Cof family protein YP_002037846.1 1114444 R 512566 CDS YP_002037847.1 194398150 6480471 complement(1115235..1118774) 1 NC_011072.1 identified by match to protein family HMM PF02463; match to protein family HMM PF06470; chromosome segregation protein smc 1118774 6480471 SPG_1137 Streptococcus pneumoniae G54 chromosome segregation protein smc YP_002037847.1 1115235 R 512566 CDS YP_002037848.1 194398097 6480464 complement(1118765..1119463) 1 NC_011072.1 cytoplasmic enzyme involved in processing rRNA and some mRNAs; substrates typically have dsRNA regions; forms a homodimer; have N-terminal nuclease and C-terminal RNA-binding domains; requires magnesium as preferred ion for activity; ribonuclease III 1119463 rnc 6480464 rnc Streptococcus pneumoniae G54 ribonuclease III YP_002037848.1 1118765 R 512566 CDS YP_002037849.1 194398573 6480426 complement(1119781..1120767) 1 NC_011072.1 identified by match to protein family HMM PF00478; match to protein family HMM TIGR01306; guanosine 5'-monophosphate oxidoreductase 1120767 guaC 6480426 guaC Streptococcus pneumoniae G54 guanosine 5'-monophosphate oxidoreductase YP_002037849.1 1119781 R 512566 CDS YP_002037850.1 194396838 6479152 complement(1120942..1122168) 1 NC_011072.1 hypothetical protein 1122168 6479152 SPG_1141 Streptococcus pneumoniae G54 hypothetical protein YP_002037850.1 1120942 R 512566 CDS YP_002037851.1 194397372 6479359 complement(1122245..1123837) 1 NC_011072.1 putative endonuclease 1123837 6479359 SPG_1142 Streptococcus pneumoniae G54 putative endonuclease YP_002037851.1 1122245 R 512566 CDS YP_002037852.1 194397855 6480535 complement(1123871..1124176) 1 NC_011072.1 putative endonuclease 1124176 6480535 SPG_1143 Streptococcus pneumoniae G54 putative endonuclease YP_002037852.1 1123871 R 512566 CDS YP_002037853.1 194398330 6480262 complement(1124342..1124503) 1 NC_011072.1 hypothetical protein 1124503 6480262 SPG_1144 Streptococcus pneumoniae G54 hypothetical protein YP_002037853.1 1124342 R 512566 CDS YP_002037854.1 194396846 6479291 complement(1124493..1124666) 1 NC_011072.1 hypothetical protein 1124666 6479291 SPG_1145 Streptococcus pneumoniae G54 hypothetical protein YP_002037854.1 1124493 R 512566 CDS YP_002037855.1 194397326 6479596 complement(1124766..1124909) 1 NC_011072.1 hypothetical protein 1124909 6479596 SPG_1146 Streptococcus pneumoniae G54 hypothetical protein YP_002037855.1 1124766 R 512566 CDS YP_002037856.1 194397849 6479871 complement(1125128..1125487) 1 NC_011072.1 hypothetical protein 1125487 6479871 SPG_1147 Streptococcus pneumoniae G54 hypothetical protein YP_002037856.1 1125128 R 512566 CDS YP_002037857.1 194398276 6480123 complement(1125491..1125760) 1 NC_011072.1 identified by match to protein family HMM PF06961; hypothetical protein 1125760 6480123 SPG_1148 Streptococcus pneumoniae G54 hypothetical protein YP_002037857.1 1125491 R 512566 CDS YP_002037858.1 194398701 6478658 complement(1125757..1126548) 1 NC_011072.1 identified by similarity to SP:Q8DPJ4; match to protein family HMM PF00180; match to protein family HMM TIGR00169; 3-isopropylmalate dehydrogenase 1126548 6478658 SPG_1149 Streptococcus pneumoniae G54 3-isopropylmalate dehydrogenase YP_002037858.1 1125757 R 512566 CDS YP_002037859.1 194397154 6479133 complement(1126639..1126794) 1 NC_011072.1 3-isopropylmalate dehydrogenase 1126794 6479133 SPG_1150 Streptococcus pneumoniae G54 3-isopropylmalate dehydrogenase YP_002037859.1 1126639 R 512566 CDS YP_002037860.1 194397503 6479016 complement(1126806..1127900) 1 NC_011072.1 identified by match to protein family HMM PF00682; match to protein family HMM PF08502; 2-isopropylmalate synthase 1127900 6479016 SPG_1151 Streptococcus pneumoniae G54 2-isopropylmalate synthase YP_002037860.1 1126806 R 512566 CDS YP_002037861.1 194398089 6479265 complement(1127919..1128575) 1 NC_011072.1 identified by match to protein family HMM PF04237; hypothetical protein 1128575 6479265 SPG_1152 Streptococcus pneumoniae G54 hypothetical protein YP_002037861.1 1127919 R 512566 CDS YP_002037863.1 194397750 6478962 complement(1129112..1129252) 1 NC_011072.1 contains potential frameshift; copper homeostasis protein CutC 1129252 6478962 SPG_1154 Streptococcus pneumoniae G54 copper homeostasis protein CutC YP_002037863.1 1129112 R 512566 CDS YP_002037864.1 194398549 6479999 complement(1129345..1129704) 1 NC_011072.1 identified by match to protein family HMM PF04304; hypothetical protein 1129704 6479999 SPG_1155 Streptococcus pneumoniae G54 hypothetical protein YP_002037864.1 1129345 R 512566 CDS YP_002037865.1 194396864 6480675 complement(1129810..1131897) 1 NC_011072.1 catalyzes the ATP-dependent breakage of single-stranded DNA followed by passage and rejoining, maintains net negative superhelicity; DNA topoisomerase I 1131897 topA 6480675 topA Streptococcus pneumoniae G54 DNA topoisomerase I YP_002037865.1 1129810 R 512566 CDS YP_002037866.1 194397038 6479053 complement(1132064..1133083) 1 NC_011072.1 identified by match to protein family HMM PF04087; hypothetical protein 1133083 6479053 SPG_1157 Streptococcus pneumoniae G54 hypothetical protein YP_002037866.1 1132064 R 512566 CDS YP_002037867.1 194397452 6479942 1133007..1133141 1 NC_011072.1 identified by glimmer; putative; hypothetical protein 1133141 6479942 SPG_1158 Streptococcus pneumoniae G54 hypothetical protein YP_002037867.1 1133007 D 512566 CDS YP_002037868.1 194398746 6480097 complement(1133651..1133893) 1 NC_011072.1 identified by glimmer; putative; hypothetical protein 1133893 6480097 SPG_1159 Streptococcus pneumoniae G54 hypothetical protein YP_002037868.1 1133651 R 512566 CDS YP_002037869.1 194398138 6478648 complement(1133991..1134839) 1 NC_011072.1 DNA processing chain A: Also known as smf protein (name of uncharacterized protein in E. coli); identified by match to protein family HMM PF02481; match to protein family HMM TIGR00732; DNA processing Smf protein 1134839 dprA 6478648 dprA Streptococcus pneumoniae G54 DNA processing Smf protein YP_002037869.1 1133991 R 512566 CDS YP_002037870.1 194398109 6480121 complement(1134925..1135614) 1 NC_011072.1 identified by match to protein family HMM PF00483; CTP:phosphocholine cytidylyltransferase 1135614 6480121 SPG_1161 Streptococcus pneumoniae G54 CTP:phosphocholine cytidylyltransferase YP_002037870.1 1134925 R 512566 CDS YP_002037871.1 194397489 6479066 complement(1135626..1136504) 1 NC_011072.1 identified by match to protein family HMM PF00892; LicB protein 1136504 6479066 SPG_1162 Streptococcus pneumoniae G54 LicB protein YP_002037871.1 1135626 R 512566 CDS YP_002037872.1 194397037 6480639 complement(1136494..1137363) 1 NC_011072.1 identified by match to protein family HMM PF01633; match to protein family HMM PF01636; choline kinase 1137363 6480639 SPG_1163 Streptococcus pneumoniae G54 choline kinase YP_002037872.1 1136494 R 512566 CDS YP_002037873.1 194397911 6479976 complement(1137380..1138402) 1 NC_011072.1 identified by match to protein family HMM PF08240; alcohol dehydrogenase 1138402 6479976 SPG_1164 Streptococcus pneumoniae G54 alcohol dehydrogenase YP_002037873.1 1137380 R 512566 CDS YP_002037874.1 194396774 6479371 complement(1138407..1139114) 1 NC_011072.1 4-diphosphocytidyl-2C-methyl-D-erythritol synthase; MEP cytidylyltransferase; MCT; catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate; involved in isoprenoid and isopentenyl-PP biosynthesis; forms homodimers; 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 1139114 ispD 6479371 ispD Streptococcus pneumoniae G54 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase YP_002037874.1 1138407 R 512566 CDS YP_002037875.1 194398302 6479655 1139450..1140937 1 NC_011072.1 identified by match to protein family HMM PF01943; polysaccharide biosynthesis protein 1140937 6479655 SPG_1166 Streptococcus pneumoniae G54 polysaccharide biosynthesis protein YP_002037875.1 1139450 D 512566 CDS YP_002037876.1 194398160 6479572 1140947..1141750 1 NC_011072.1 identified by match to protein family HMM PF04991; phosphotransferase LicD1 1141750 6479572 SPG_1167 Streptococcus pneumoniae G54 phosphotransferase LicD1 YP_002037876.1 1140947 D 512566 CDS YP_002037877.1 194397539 6480804 1141752..1142561 1 NC_011072.1 identified by match to protein family HMM PF04991; phosphotransferase LicD2 1142561 6480804 SPG_1168 Streptococcus pneumoniae G54 phosphotransferase LicD2 YP_002037877.1 1141752 D 512566 CDS YP_002037878.1 194398207 6479397 complement(1142837..1146013) 1 NC_011072.1 four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate; CarB is responsible for the amidotransferase activity; carbamoyl phosphate synthase large subunit 1146013 carB 6479397 carB Streptococcus pneumoniae G54 carbamoyl phosphate synthase large subunit YP_002037878.1 1142837 R 512566 CDS YP_002037879.1 194398063 6479426 complement(1146326..1147405) 1 NC_011072.1 catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers; carbamoyl phosphate synthase small subunit 1147405 carA 6479426 carA Streptococcus pneumoniae G54 carbamoyl phosphate synthase small subunit YP_002037879.1 1146326 R 512566 CDS YP_002037880.1 194397469 6479617 complement(1147455..1148378) 1 NC_011072.1 catalyzes the transfer of the carbamoyl moiety from carbamoyl phosphate to L- aspartate in pyrimidine biosynthesis; aspartate carbamoyltransferase catalytic subunit 1148378 pyrB 6479617 pyrB Streptococcus pneumoniae G54 aspartate carbamoyltransferase catalytic subunit YP_002037880.1 1147455 R 512566 CDS YP_002037881.1 194398459 6480023 complement(1148397..1148918) 1 NC_011072.1 regulates pyrimidine biosynthesis by binding to the mRNA of the pyr genes, also has been shown to have uracil phosphoribosyltransferase activity; bifunctional pyrimidine regulatory protein PyrR uracil phosphoribosyltransferase 1148918 pyrR 6480023 pyrR Streptococcus pneumoniae G54 bifunctional pyrimidine regulatory protein PyrR uracil phosphoribosyltransferase YP_002037881.1 1148397 R 512566 CDS YP_002037882.1 194398645 6480740 complement(1149128..1149757) 1 NC_011072.1 identified by match to protein family HMM PF00633; match to protein family HMM PF00730; match to protein family HMM TIGR01083; endonuclease III 1149757 nth 6480740 nth Streptococcus pneumoniae G54 endonuclease III YP_002037882.1 1149128 R 512566 CDS YP_002037883.1 194398333 6479431 complement(1149757..1150299) 1 NC_011072.1 identified by match to protein family HMM PF02620; hypothetical protein 1150299 6479431 SPG_1174 Streptococcus pneumoniae G54 hypothetical protein YP_002037883.1 1149757 R 512566 CDS YP_002037884.1 194396899 6480825 1150469..1150609 1 NC_011072.1 identified by glimmer; putative; hypothetical protein 1150609 6480825 SPG_1175 Streptococcus pneumoniae G54 hypothetical protein YP_002037884.1 1150469 D 512566 CDS YP_002037885.1 194397400 6478659 1151024..1152583 1 NC_011072.1 identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 1152583 6478659 SPG_1176 Streptococcus pneumoniae G54 ABC transporter ATP-binding protein YP_002037885.1 1151024 D 512566 CDS YP_002037886.1 194398121 6480609 complement(1152732..1153631) 1 NC_011072.1 putative metalloprotease; heat shock protein HtpX 1153631 6480609 SPG_1177 Streptococcus pneumoniae G54 heat shock protein HtpX YP_002037886.1 1152732 R 512566 CDS YP_002037887.1 194398565 6479711 complement(1153633..1154193) 1 NC_011072.1 identified by match to protein family HMM PF04011; cytoplasmic membrane protein 1154193 6479711 SPG_1178 Streptococcus pneumoniae G54 cytoplasmic membrane protein YP_002037887.1 1153633 R 512566 CDS YP_002037888.1 194397570 6478813 1154287..1155000 1 NC_011072.1 glucose-inhibited division protein B; SAM-dependent methyltransferase; methylates the N7 position of guanosine in position 527 of 16S rRNA; 16S rRNA methyltransferase GidB 1155000 gidB 6478813 gidB Streptococcus pneumoniae G54 16S rRNA methyltransferase GidB YP_002037888.1 1154287 D 512566 CDS YP_002037889.1 194398043 6478826 1155254..1156537 1 NC_011072.1 identified by match to protein family HMM PF00860; match to protein family HMM TIGR00801; uracil permease (pyrP) 1156537 pyrP 6478826 pyrP Streptococcus pneumoniae G54 uracil permease (pyrP) YP_002037889.1 1155254 D 512566 CDS YP_002037890.1 194398377 6478671 complement(1156732..1158303) 1 NC_011072.1 identified by match to protein family HMM PF00448; match to protein family HMM PF02881; match to protein family HMM PF02978; match to protein family HMM TIGR00959; signal recognition particle protein 1158303 6478671 SPG_1181 Streptococcus pneumoniae G54 signal recognition particle protein YP_002037890.1 1156732 R 512566 CDS YP_002037891.1 194397106 6478675 complement(1158315..1158647) 1 NC_011072.1 identified by glimmer; putative; putative DNA-binding protein 1158647 6478675 SPG_1182 Streptococcus pneumoniae G54 putative DNA-binding protein YP_002037891.1 1158315 R 512566 CDS YP_002037892.1 194397440 6479913 complement(1158738..1159115) 1 NC_011072.1 identified by match to protein family HMM PF09148; hypothetical protein 1159115 6479913 SPG_1183 Streptococcus pneumoniae G54 hypothetical protein YP_002037892.1 1158738 R 512566 CDS YP_002037893.1 194397776 6480309 1159187..1160491 1 NC_011072.1 identified by match to protein family HMM PF01966; hypothetical protein 1160491 6480309 SPG_1184 Streptococcus pneumoniae G54 hypothetical protein YP_002037893.1 1159187 D 512566 CDS YP_002037894.1 194397310 6480433 1160504..1161310 1 NC_011072.1 identified by match to protein family HMM PF00702; match to protein family HMM PF05116; match to protein family HMM PF08282; match to protein family HMM TIGR00099; match to protein family HMM TIGR01484; Cof family protein 1161310 6480433 SPG_1185 Streptococcus pneumoniae G54 Cof family protein YP_002037894.1 1160504 D 512566 CDS YP_002037895.1 194397813 6480159 complement(1161480..1161827) 1 NC_011072.1 this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site; 50S ribosomal protein L19 1161827 rplS 6480159 rplS Streptococcus pneumoniae G54 50S ribosomal protein L19 YP_002037895.1 1161480 R 512566 CDS YP_002037896.1 194398004 6480182 complement(1161946..1162275) 1 NC_011072.1 may be involved in chromosome condensation; overexpression in Escherichia coli protects against decondensation by camphor; overexpressing the protein results in an increase in supercoiling; camphor resistance protein CrcB 1162275 6480182 SPG_1188 Streptococcus pneumoniae G54 camphor resistance protein CrcB YP_002037896.1 1161946 R 512566 CDS YP_002037897.1 194396861 6479412 complement(1162269..1162643) 1 NC_011072.1 may be involved in chromosome condensation; overexpression in Escherichia coli protects against decondensation by camphor; overexpressing the protein results in an increase in supercoiling; camphor resistance protein CrcB 1162643 6479412 SPG_1189 Streptococcus pneumoniae G54 camphor resistance protein CrcB YP_002037897.1 1162269 R 512566 CDS YP_002037898.1 194396902 6478835 complement(1162640..1162906) 1 NC_011072.1 identified by match to protein family HMM PF01817; match to protein family HMM TIGR01805; hypothetical protein 1162906 6478835 SPG_1190 Streptococcus pneumoniae G54 hypothetical protein YP_002037898.1 1162640 R 512566 CDS YP_002037899.1 194397393 6479802 complement(1163022..1163465) 1 NC_011072.1 An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group; flavodoxin 1163465 6479802 SPG_1191 Streptococcus pneumoniae G54 flavodoxin YP_002037899.1 1163022 R 512566 CDS YP_002037900.1 194397733 6480491 1163569..1164504 1 NC_011072.1 identified by match to protein family HMM PF01368; hypothetical protein 1164504 6480491 SPG_1192 Streptococcus pneumoniae G54 hypothetical protein YP_002037900.1 1163569 D 512566 CDS YP_002037901.1 194398450 6480702 1164600..1164842 1 NC_011072.1 RpmE2; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster do not have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome; 50S ribosomal protein L31 type B 1164842 rpmE2 6480702 rpmE2 Streptococcus pneumoniae G54 50S ribosomal protein L31 type B YP_002037901.1 1164600 D 512566 CDS YP_002037902.1 194397287 6480127 complement(1164899..1165117) 1 NC_011072.1 identified by glimmer; putative; hypothetical protein 1165117 6480127 SPG_1194 Streptococcus pneumoniae G54 hypothetical protein YP_002037902.1 1164899 R 512566 CDS YP_002037903.1 194397908 6478964 complement(1165114..1165275) 1 NC_011072.1 transposase 1165275 6478964 SPG_1195 Streptococcus pneumoniae G54 transposase YP_002037903.1 1165114 R 512566 CDS YP_002037904.1 194398756 6478897 complement(1165425..1165676) 1 NC_011072.1 IS630-SpnII transposase 1165676 6478897 SPG_1196 Streptococcus pneumoniae G54 IS630-SpnII transposase YP_002037904.1 1165425 R 512566 CDS YP_002037905.1 194396681 6480746 1166202..1167548 1 NC_011072.1 converts 2-oxoglutarate to glutamate; in Escherichia coli this enzyme plays a role in glutamate synthesis when the cell is under energy restriction; uses NADPH; forms a homohexamer; glutamate dehydrogenase 1167548 gdhA 6480746 gdhA Streptococcus pneumoniae G54 glutamate dehydrogenase YP_002037905.1 1166202 D 512566 CDS YP_002037906.1 194397041 6479876 complement(1168054..1168224) 1 NC_011072.1 hypothetical protein 1168224 6479876 SPG_1198 Streptococcus pneumoniae G54 hypothetical protein YP_002037906.1 1168054 R 512566 CDS YP_002037907.1 194397654 6479684 complement(1168237..1168683) 1 NC_011072.1 identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 1168683 6479684 SPG_1199 Streptococcus pneumoniae G54 ABC transporter ATP-binding protein YP_002037907.1 1168237 R 512566 CDS YP_002037908.1 194397365 6478721 complement(1168873..1169220) 1 NC_011072.1 transposase 1169220 6478721 SPG_1200 Streptococcus pneumoniae G54 transposase YP_002037908.1 1168873 R 512566 CDS YP_002037909.1 194397922 6480072 complement(1169237..1169635) 1 NC_011072.1 transposase 1169635 6480072 SPG_1201 Streptococcus pneumoniae G54 transposase YP_002037909.1 1169237 R 512566 CDS YP_002037910.1 194396855 6479028 complement(1169728..1169886) 1 NC_011072.1 IS66-Spn1 transposase 1169886 6479028 SPG_1202 Streptococcus pneumoniae G54 IS66-Spn1 transposase YP_002037910.1 1169728 R 512566 CDS YP_002037911.1 194397026 6479245 complement(1170149..1170319) 1 NC_011072.1 IS66-Spn1 transposase 1170319 6479245 SPG_1203 Streptococcus pneumoniae G54 IS66-Spn1 transposase YP_002037911.1 1170149 R 512566 CDS YP_002037912.1 194397514 6480010 complement(1170481..1170792) 1 NC_011072.1 IS66-Spn1 transposase 1170792 6480010 SPG_1204 Streptococcus pneumoniae G54 IS66-Spn1 transposase YP_002037912.1 1170481 R 512566 CDS YP_002037913.1 194398257 6479380 1170954..1171106 1 NC_011072.1 IS630-SpnII transposase 1171106 6479380 SPG_1205 Streptococcus pneumoniae G54 IS630-SpnII transposase YP_002037913.1 1170954 D 512566 CDS YP_002037914.1 194396975 6478971 complement(1171375..1171698) 1 NC_011072.1 identified by match to protein family HMM PF05717; IS66-Spn1 transposase 1171698 6478971 SPG_1206 Streptococcus pneumoniae G54 IS66-Spn1 transposase YP_002037914.1 1171375 R 512566 CDS YP_002037915.1 194397552 6479811 complement(1171679..1171918) 1 NC_011072.1 IS66-Spn1 transposase 1171918 6479811 SPG_1207 Streptococcus pneumoniae G54 IS66-Spn1 transposase YP_002037915.1 1171679 R 512566 CDS YP_002037916.1 194397894 6479288 complement(1172137..1172748) 1 NC_011072.1 produces ATP from ADP in the presence of a proton gradient across the membrane; the D subunit is part of the catalytic core of the ATP synthase complex; V-type ATP synthase subunit D 1172748 ntpD 6479288 ntpD Streptococcus pneumoniae G54 V-type ATP synthase subunit D YP_002037916.1 1172137 R 512566 CDS YP_002037917.1 194398442 6479508 complement(1172771..1174156) 1 NC_011072.1 produces ATP from ADP in the presence of a proton gradient across the membrane; the B subunit is part of the catalytic core of the ATP synthase complex; V-type ATP synthase subunit B 1174156 ntpB 6479508 ntpB Streptococcus pneumoniae G54 V-type ATP synthase subunit B YP_002037917.1 1172771 R 512566 CDS YP_002037918.1 194397388 6480551 complement(1174157..1175932) 1 NC_011072.1 produces ATP from ADP in the presence of a proton gradient across the membrane; the A subunit is part of the catalytic core of the ATP synthase complex; V-type ATP synthase subunit A 1175932 ntpA 6480551 ntpA Streptococcus pneumoniae G54 V-type ATP synthase subunit A YP_002037918.1 1174157 R 512566 CDS YP_002037919.1 194398525 6480315 complement(1175995..1176315) 1 NC_011072.1 produces ATP from ADP in the presence of a proton gradient across the membrane; the F subunit is part of the catalytic core of the ATP synthase complex; V-type ATP synthase subunit F 1176315 ntpG 6480315 ntpG Streptococcus pneumoniae G54 V-type ATP synthase subunit F YP_002037919.1 1175995 R 512566 CDS YP_002037920.1 194397828 6480148 complement(1176305..1177312) 1 NC_011072.1 Takase, K. (1994) Journ. Biol. Chem. 269(15) 11037-11044; identified by match to protein family HMM PF01992; V-type sodium ATP synthase subunit C 1177312 ntpC 6480148 ntpC Streptococcus pneumoniae G54 V-type sodium ATP synthase subunit C YP_002037920.1 1176305 R 512566 CDS YP_002037921.1 194397330 6480452 complement(1177377..1177958) 1 NC_011072.1 Takase, K. (1994) Journ. Biol. Chem. 269(15) 11037-11044; V-type sodium ATP synthase subunit E 1177958 ntpE 6480452 ntpE Streptococcus pneumoniae G54 V-type sodium ATP synthase subunit E YP_002037921.1 1177377 R 512566 CDS YP_002037922.1 194397143 6480750 complement(1177992..1178468) 1 NC_011072.1 produces ATP from ADP in the presence of a proton gradient across the membrane; the K subunit is a nonenzymatic component which binds the dimeric form by interacting with the G and E subunits; V-type ATP synthase subunit K 1178468 ntpK 6480750 ntpK Streptococcus pneumoniae G54 V-type ATP synthase subunit K YP_002037922.1 1177992 R 512566 CDS YP_002037923.1 194398305 6480271 complement(1178484..1180475) 1 NC_011072.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit I is part of the membrane proton channel.; V-type ATP synthase subunit I 1180475 ntpI 6480271 ntpI Streptococcus pneumoniae G54 V-type ATP synthase subunit I YP_002037923.1 1178484 R 512566 CDS YP_002037924.1 194397646 6479393 complement(1180465..1180788) 1 NC_011072.1 identified by glimmer; putative; hypothetical protein 1180788 6479393 SPG_1216 Streptococcus pneumoniae G54 hypothetical protein YP_002037924.1 1180465 R 512566 CDS YP_002037925.1 194397155 6479231 complement(1180813..1181703) 1 NC_011072.1 identified by match to protein family HMM PF00480; ROK family protein 1181703 6479231 SPG_1217 Streptococcus pneumoniae G54 ROK family protein YP_002037925.1 1180813 R 512566 CDS YP_002037926.1 194396852 6479348 complement(1181860..1182969) 1 NC_011072.1 identified by similarity to RF:ZP_00403965.1; match to protein family HMM PF01118; match to protein family HMM PF01408; match to protein family HMM PF02894; match to protein family HMM PF03447; hypothetical protein 1182969 6479348 SPG_1218 Streptococcus pneumoniae G54 hypothetical protein YP_002037926.1 1181860 R 512566 CDS YP_002037927.1 194398115 6478950 complement(1183009..1185231) 1 NC_011072.1 identified by match to protein family HMM PF02012; match to protein family HMM PF02973; neuraminidase C 1185231 nanC 6478950 nanC Streptococcus pneumoniae G54 neuraminidase C YP_002037927.1 1183009 R 512566 CDS YP_002037928.1 194397938 6480645 complement(1185233..1185691) 1 NC_011072.1 identified by match to protein family HMM PF04074; match to protein family HMM TIGR00022; hypothetical protein 1185691 6480645 SPG_1220 Streptococcus pneumoniae G54 hypothetical protein YP_002037928.1 1185233 R 512566 CDS YP_002037929.1 194397451 6479446 complement(1185710..1187251) 1 NC_011072.1 identified by match to protein family HMM PF00474; match to protein family HMM TIGR00813; sodium symporter family protein 1187251 6479446 SPG_1221 Streptococcus pneumoniae G54 sodium symporter family protein YP_002037929.1 1185710 R 512566 CDS YP_002037930.1 194398415 6480505 complement(1187279..1188196) 1 NC_011072.1 identified by match to protein family HMM PF00701; dihydrodipicolinate synthetase family 1188196 6480505 SPG_1222 Streptococcus pneumoniae G54 dihydrodipicolinate synthetase family YP_002037930.1 1187279 R 512566 CDS YP_002037931.1 194397959 6480466 complement(1188221..1188922) 1 NC_011072.1 Converts N-acetylmannosamine-6-phosphate to N-acetylglucosamine-6-phosphate; N-acetylmannosamine-6-phosphate 2-epimerase 1188922 6480466 SPG_1223 Streptococcus pneumoniae G54 N-acetylmannosamine-6-phosphate 2-epimerase YP_002037931.1 1188221 R 512566 CDS YP_002037932.1 194398222 6479527 complement(1188927..1189736) 1 NC_011072.1 identified by match to protein family HMM PF01380; match to protein family HMM PF01418; RpiR family transcriptional regulator 1189736 6479527 SPG_1224 Streptococcus pneumoniae G54 RpiR family transcriptional regulator YP_002037932.1 1188927 R 512566 CDS YP_002037933.1 194396731 6479260 complement(1190136..1190723) 1 NC_011072.1 identified by match to protein family HMM PF02517; Tn5253 CAAX amino terminal protease family 1190723 6479260 SPG_1225 Streptococcus pneumoniae G54 Tn5253 CAAX amino terminal protease family YP_002037933.1 1190136 R 512566 CDS YP_002037934.1 194398684 6479751 complement(1190850..1190966) 1 NC_011072.1 hypothetical protein 1190966 6479751 SPG_1226 Streptococcus pneumoniae G54 hypothetical protein YP_002037934.1 1190850 R 512566 CDS YP_002037935.1 194398035 6479561 complement(1190980..1191360) 1 NC_011072.1 Tn5253 hypothetical protein 1191360 6479561 SPG_1227 Streptococcus pneumoniae G54 Tn5253 hypothetical protein YP_002037935.1 1190980 R 512566 CDS YP_002037936.1 194397743 6478929 complement(1191353..1191676) 1 NC_011072.1 Tn5253 hypothetical protein 1191676 6478929 SPG_1228 Streptococcus pneumoniae G54 Tn5253 hypothetical protein YP_002037936.1 1191353 R 512566 CDS YP_002037937.1 194397138 6480427 complement(1191684..1191938) 1 NC_011072.1 identified by glimmer; putative; hypothetical protein 1191938 6480427 SPG_1229 Streptococcus pneumoniae G54 hypothetical protein YP_002037937.1 1191684 R 512566 CDS YP_002037938.1 194397025 6480055 complement(1191935..1192108) 1 NC_011072.1 hypothetical protein 1192108 6480055 SPG_1230 Streptococcus pneumoniae G54 hypothetical protein YP_002037938.1 1191935 R 512566 CDS YP_002037939.1 194397505 6480448 complement(1192417..1194336) 1 NC_011072.1 identified by match to protein family HMM PF00009; match to protein family HMM PF00679; match to protein family HMM PF03144; match to protein family HMM PF03764; match to protein family HMM TIGR00231; tetracycline resistance protein TetM 1194336 6480448 SPG_1231 Streptococcus pneumoniae G54 tetracycline resistance protein TetM YP_002037939.1 1192417 R 512566 CDS YP_002037940.1 194397036 6479003 complement(1194713..1195630) 1 NC_011072.1 identified by similarity to RF:YP_133682.1; Tn5251 hypothetical protein 1195630 6479003 SPG_1232 Streptococcus pneumoniae G54 Tn5251 hypothetical protein YP_002037940.1 1194713 R 512566 CDS YP_002037941.1 194398679 6479955 complement(1195645..1196646) 1 NC_011072.1 identified by match to protein family HMM PF00877; Tn5251 lipoprotein NLP/P60 family 1196646 6479955 SPG_1233 Streptococcus pneumoniae G54 Tn5251 lipoprotein NLP/P60 family YP_002037941.1 1195645 R 512566 CDS YP_002037942.1 194398204 6478966 complement(1196643..1198754) 1 NC_011072.1 Tn5251 membrane protein putative 1198754 6478966 SPG_1234 Streptococcus pneumoniae G54 Tn5251 membrane protein putative YP_002037942.1 1196643 R 512566 CDS YP_002037943.1 194397304 6478834 complement(1198823..1201270) 1 NC_011072.1 Tn5251 hypothetical protein 1201270 6478834 SPG_1235 Streptococcus pneumoniae G54 Tn5251 hypothetical protein YP_002037943.1 1198823 R 512566 CDS YP_002037944.1 194396712 6478701 complement(1201254..1201646) 1 NC_011072.1 Tn5251 hypothetical protein 1201646 6478701 SPG_1236 Streptococcus pneumoniae G54 Tn5251 hypothetical protein YP_002037944.1 1201254 R 512566 CDS YP_002037945.1 194398388 6479731 complement(1201735..1202232) 1 NC_011072.1 identified by match to protein family HMM PF07275; Tn5251 hypothetical protein 1202232 6479731 SPG_1237 Streptococcus pneumoniae G54 Tn5251 hypothetical protein YP_002037945.1 1201735 R 512566 CDS YP_002037946.1 194397890 6478840 complement(1202349..1202570) 1 NC_011072.1 Tn5251 hypothetical protein 1202570 6478840 SPG_1238 Streptococcus pneumoniae G54 Tn5251 hypothetical protein YP_002037946.1 1202349 R 512566 CDS YP_002037947.1 194396700 6480565 1202750..1203397 1 NC_011072.1 identified by match to protein family HMM PF01610; transposase 1203397 6480565 SPG_1239 Streptococcus pneumoniae G54 transposase YP_002037947.1 1202750 D 512566 CDS YP_002037948.1 194397172 6479748 1203357..1203983 1 NC_011072.1 identified by match to protein family HMM PF01610; transposase 1203983 6479748 SPG_1240 Streptococcus pneumoniae G54 transposase YP_002037948.1 1203357 D 512566 CDS YP_002037949.1 194398695 6479254 complement(1204240..1204977) 1 NC_011072.1 identified by match to protein family HMM PF00398; rRNA adenine N-6-methyltransferase ErmB 1204977 ermB 6479254 ermB Streptococcus pneumoniae G54 rRNA adenine N-6-methyltransferase ErmB YP_002037949.1 1204240 R 512566 CDS YP_002037950.1 194397840 6479108 complement(1205234..1206652) 1 NC_011072.1 identified by match to protein family HMM PF01381; match to protein family HMM PF02486; match to protein family HMM PF07764; Tn5251 transcriptional regulator Cro/CI family 1206652 6479108 SPG_1242 Streptococcus pneumoniae G54 Tn5251 transcriptional regulator Cro/CI family YP_002037950.1 1205234 R 512566 CDS YP_002037951.1 194397235 6480116 complement(1206830..1208215) 1 NC_011072.1 identified by match to protein family HMM PF01580; Tn5251 FtsK/SpoIIIE family protein 1208215 6480116 SPG_1243 Streptococcus pneumoniae G54 Tn5251 FtsK/SpoIIIE family protein YP_002037951.1 1206830 R 512566 CDS YP_002037952.1 194396880 6480169 complement(1208244..1208627) 1 NC_011072.1 identified by match to protein family HMM PF06125; Tn5251 hypothetical protein 1208627 6480169 SPG_1244 Streptococcus pneumoniae G54 Tn5251 hypothetical protein YP_002037952.1 1208244 R 512566 CDS YP_002037953.1 194398214 6479306 complement(1208646..1208960) 1 NC_011072.1 identified by match to protein family HMM PF06125; Tn5251 hypothetical protein 1208960 6479306 SPG_1245 Streptococcus pneumoniae G54 Tn5251 hypothetical protein YP_002037953.1 1208646 R 512566 CDS YP_002037954.1 194397485 6478996 complement(1209362..1209475) 1 NC_011072.1 identified by glimmer; putative; hypothetical protein 1209475 6478996 SPG_1246 Streptococcus pneumoniae G54 hypothetical protein YP_002037954.1 1209362 R 512566 CDS YP_002037955.1 194397827 6480524 1209724..1210587 1 NC_011072.1 identified by match to protein family HMM PF01381; putative transcriptional activator 1210587 6480524 SPG_1247 Streptococcus pneumoniae G54 putative transcriptional activator YP_002037955.1 1209724 D 512566 CDS YP_002037956.1 194397363 6480451 complement(1210692..1210940) 1 NC_011072.1 hypothetical protein 1210940 6480451 SPG_1248 Streptococcus pneumoniae G54 hypothetical protein YP_002037956.1 1210692 R 512566 CDS YP_002037957.1 194396920 6480070 complement(1211144..1211617) 1 NC_011072.1 relaxase 1211617 6480070 SPG_1249 Streptococcus pneumoniae G54 relaxase YP_002037957.1 1211144 R 512566 CDS YP_002037958.1 194397251 6480020 complement(1211631..1212968) 1 NC_011072.1 identified by match to protein family HMM PF03432; Tn5253 relaxase 1212968 6480020 SPG_1250 Streptococcus pneumoniae G54 Tn5253 relaxase YP_002037958.1 1211631 R 512566 CDS YP_002037959.1 194397039 6479791 complement(1212955..1213320) 1 NC_011072.1 identified by match to protein family HMM PF05713; Tn5253 hypothetical protein 1213320 6479791 SPG_1251 Streptococcus pneumoniae G54 Tn5253 hypothetical protein YP_002037959.1 1212955 R 512566 CDS YP_002037960.1 194397484 6480444 complement(1213325..1213681) 1 NC_011072.1 Tn5253 hypothetical protein 1213681 6480444 SPG_1252 Streptococcus pneumoniae G54 Tn5253 hypothetical protein YP_002037960.1 1213325 R 512566 CDS YP_002037961.1 194398251 6479884 1214044..1215219 1 NC_011072.1 identified by glimmer; putative; hypothetical protein 1215219 6479884 SPG_1253 Streptococcus pneumoniae G54 hypothetical protein YP_002037961.1 1214044 D 512566 CDS YP_002037962.1 194398690 6478645 complement(1215305..1217122) 1 NC_011072.1 identified by match to protein family HMM PF00580; ATP-dependent DNA helicase 1217122 6478645 SPG_1254 Streptococcus pneumoniae G54 ATP-dependent DNA helicase YP_002037962.1 1215305 R 512566 CDS YP_002037963.1 194397225 6479001 complement(1217109..1219178) 1 NC_011072.1 DNA helicase associated protein 1219178 6479001 SPG_1255 Streptococcus pneumoniae G54 DNA helicase associated protein YP_002037963.1 1217109 R 512566 CDS YP_002037964.1 194398365 6480797 1219829..1221079 1 NC_011072.1 identified by glimmer; putative; hypothetical protein 1221079 6480797 SPG_1257 Streptococcus pneumoniae G54 hypothetical protein YP_002037964.1 1219829 D 512566 CDS YP_002037965.1 194397754 6480068 complement(1221076..1221648) 1 NC_011072.1 hypothetical protein 1221648 6480068 SPG_1256 Streptococcus pneumoniae G54 hypothetical protein YP_002037965.1 1221076 R 512566 CDS YP_002037966.1 194396828 6479866 1221742..1222638 1 NC_011072.1 identified by match to protein family HMM PF00589; match to protein family HMM PF02899; integrase 1222638 6479866 SPG_1258 Streptococcus pneumoniae G54 integrase YP_002037966.1 1221742 D 512566 CDS YP_002037967.1 194396765 6479307 complement(1223016..1223396) 1 NC_011072.1 Tn5253 hypothetical protein 1223396 6479307 SPG_1259 Streptococcus pneumoniae G54 Tn5253 hypothetical protein YP_002037967.1 1223016 R 512566 CDS YP_002037968.1 194398482 6479849 1223457..1223597 1 NC_011072.1 transposase 1223597 6479849 SPG_1260 Streptococcus pneumoniae G54 transposase YP_002037968.1 1223457 D 512566 CDS YP_002037969.1 194397159 6479939 complement(1223756..1223983) 1 NC_011072.1 identified by glimmer; putative; hypothetical protein 1223983 6479939 SPG_1261 Streptococcus pneumoniae G54 hypothetical protein YP_002037969.1 1223756 R 512566 CDS YP_002037970.1 194397624 6479200 complement(1223974..1224606) 1 NC_011072.1 identified by glimmer; putative; hypothetical protein 1224606 6479200 SPG_1262 Streptococcus pneumoniae G54 hypothetical protein YP_002037970.1 1223974 R 512566 CDS YP_002037971.1 194397411 6478855 complement(1224688..1224963) 1 NC_011072.1 Tn5253 hypothetical protein 1224963 6478855 SPG_1263 Streptococcus pneumoniae G54 Tn5253 hypothetical protein YP_002037971.1 1224688 R 512566 CDS YP_002037972.1 194397761 6480390 complement(1225001..1225384) 1 NC_011072.1 Tn5253 hypothetical protein 1225384 6480390 SPG_1264 Streptococcus pneumoniae G54 Tn5253 hypothetical protein YP_002037972.1 1225001 R 512566 CDS YP_002037973.1 194396980 6479676 complement(1225381..1225614) 1 NC_011072.1 Tn5253 hypothetical protein 1225614 6479676 SPG_1265 Streptococcus pneumoniae G54 Tn5253 hypothetical protein YP_002037973.1 1225381 R 512566 CDS YP_002037974.1 194396803 6479688 complement(1225665..1226750) 1 NC_011072.1 Tn5253 hypothetical protein 1226750 6479688 SPG_1266 Streptococcus pneumoniae G54 Tn5253 hypothetical protein YP_002037974.1 1225665 R 512566 CDS YP_002037975.1 194397642 6478667 complement(1226760..1227401) 1 NC_011072.1 Tn5253 hypothetical protein 1227401 6478667 SPG_1267 Streptococcus pneumoniae G54 Tn5253 hypothetical protein YP_002037975.1 1226760 R 512566 CDS YP_002037976.1 194397142 6479208 1228560..1229423 1 NC_011072.1 identified by match to protein family HMM PF01381; match to protein family HMM TIGR01716; positive transcriptional regulator MutRfamily 1229423 6479208 SPG_1268 Streptococcus pneumoniae G54 positive transcriptional regulator MutRfamily YP_002037976.1 1228560 D 512566 CDS YP_002037977.1 194396847 6480282 complement(1229433..1231016) 1 NC_011072.1 identified by match to protein family HMM PF00005; match to protein family HMM PF00664; ABC transporter ATP-binding/permease 1231016 6480282 SPG_1269 Streptococcus pneumoniae G54 ABC transporter ATP-binding/permease YP_002037977.1 1229433 R 512566 CDS YP_002037978.1 194397686 6479149 complement(1231407..1231703) 1 NC_011072.1 Tn5253 hypothetical protein 1231703 6479149 SPG_1270 Streptococcus pneumoniae G54 Tn5253 hypothetical protein YP_002037978.1 1231407 R 512566 CDS YP_002037979.1 194398334 6478881 complement(1231717..1232001) 1 NC_011072.1 Tn5253 hypothetical protein 1232001 6478881 SPG_1271 Streptococcus pneumoniae G54 Tn5253 hypothetical protein YP_002037979.1 1231717 R 512566 CDS YP_002037980.1 194396911 6479628 complement(1232076..1238300) 1 NC_011072.1 identified by match to protein family HMM PF00176; match to protein family HMM PF00271; match to protein family HMM PF02384; match to protein family HMM PF04851; Tn5253 SNF2-related: helicase 1238300 6479628 SPG_1272 Streptococcus pneumoniae G54 Tn5253 SNF2-related: helicase YP_002037980.1 1232076 R 512566 CDS YP_002037981.1 194398031 6480579 complement(1238348..1238758) 1 NC_011072.1 Tn5253 hypothetical protein 1238758 6480579 SPG_1273 Streptococcus pneumoniae G54 Tn5253 hypothetical protein YP_002037981.1 1238348 R 512566 CDS YP_002037982.1 194398554 6479063 complement(1238910..1239476) 1 NC_011072.1 hypothetical protein 1239476 6479063 SPG_1274 Streptococcus pneumoniae G54 hypothetical protein YP_002037982.1 1238910 R 512566 CDS YP_002037983.1 194398658 6480087 complement(1239715..1242528) 1 NC_011072.1 identified by match to protein family HMM PF01551; match to protein family HMM PF05257; Tn5253 hypothetical protein 1242528 6480087 SPG_1275 Streptococcus pneumoniae G54 Tn5253 hypothetical protein YP_002037983.1 1239715 R 512566 CDS YP_002037984.1 194396961 6479266 complement(1242540..1244897) 1 NC_011072.1 Tn5253 hypothetical protein 1244897 6479266 SPG_1276 Streptococcus pneumoniae G54 Tn5253 hypothetical protein YP_002037984.1 1242540 R 512566 CDS YP_002037985.1 194397186 6480103 complement(1244848..1245207) 1 NC_011072.1 Tn5253 hypothetical protein 1245207 6480103 SPG_1277 Streptococcus pneumoniae G54 Tn5253 hypothetical protein YP_002037985.1 1244848 R 512566 CDS YP_002037986.1 194397792 6479517 complement(1245261..1246115) 1 NC_011072.1 Tn5253 hypothetical protein 1246115 6479517 SPG_1278 Streptococcus pneumoniae G54 Tn5253 hypothetical protein YP_002037986.1 1245261 R 512566 CDS YP_002037987.1 194397483 6479947 complement(1246132..1246374) 1 NC_011072.1 Tn5253 hypothetical protein 1246374 6479947 SPG_1279 Streptococcus pneumoniae G54 Tn5253 hypothetical protein YP_002037987.1 1246132 R 512566 CDS YP_002037988.1 194398494 6479883 complement(1246395..1248272) 1 NC_011072.1 identified by match to protein family HMM PF02534; Tn5253 TraG protein 1248272 6479883 SPG_1280 Streptococcus pneumoniae G54 Tn5253 TraG protein YP_002037988.1 1246395 R 512566 CDS YP_002037989.1 194396939 6480513 complement(1248272..1248760) 1 NC_011072.1 Tn5253 hypothetical protein 1248760 6480513 SPG_1281 Streptococcus pneumoniae G54 Tn5253 hypothetical protein YP_002037989.1 1248272 R 512566 CDS YP_002037990.1 194397542 6480149 complement(1248750..1249049) 1 NC_011072.1 Tn5253 bacteriocine putative 1249049 6480149 SPG_1282 Streptococcus pneumoniae G54 Tn5253 bacteriocine putative YP_002037990.1 1248750 R 512566 CDS YP_002037991.1 194397577 6479562 complement(1249643..1250275) 1 NC_011072.1 identified by match to protein family HMM PF00005; match to protein family HMM TIGR03608; bacteriocine associated ABC transporter ATP binding protein 1250275 6479562 SPG_1283 Streptococcus pneumoniae G54 bacteriocine associated ABC transporter ATP binding protein YP_002037991.1 1249643 R 512566 CDS YP_002037992.1 194398448 6478823 complement(1250277..1252286) 1 NC_011072.1 identified by match to protein family HMM TIGR01654; bacteriocine associated ABC transporter permease 1252286 6478823 SPG_1284 Streptococcus pneumoniae G54 bacteriocine associated ABC transporter permease YP_002037992.1 1250277 R 512566 CDS YP_002037993.1 194396649 6480125 complement(1252941..1253393) 1 NC_011072.1 Tn5253 hypothetical protein 1253393 6480125 SPG_1285 Streptococcus pneumoniae G54 Tn5253 hypothetical protein YP_002037993.1 1252941 R 512566 CDS YP_002037994.1 194397242 6479781 complement(1253747..1254382) 1 NC_011072.1 hypothetical protein 1254382 6479781 SPG_1286 Streptococcus pneumoniae G54 hypothetical protein YP_002037994.1 1253747 R 512566 CDS YP_002037995.1 194398095 6480412 complement(1254672..1255259) 1 NC_011072.1 identified by match to protein family HMM PF02517; Tn5253 CAAX amino terminal protease family 1255259 6480412 SPG_1287 Streptococcus pneumoniae G54 Tn5253 CAAX amino terminal protease family YP_002037995.1 1254672 R 512566 CDS YP_002037996.1 194398675 6480479 complement(1255262..1255495) 1 NC_011072.1 Tn5253 hypothetical protein 1255495 6480479 SPG_1288 Streptococcus pneumoniae G54 Tn5253 hypothetical protein YP_002037996.1 1255262 R 512566 CDS YP_002037997.1 194397090 6478761 complement(1255508..1255888) 1 NC_011072.1 Tn5253 hypothetical protein 1255888 6478761 SPG_1289 Streptococcus pneumoniae G54 Tn5253 hypothetical protein YP_002037997.1 1255508 R 512566 CDS YP_002037998.1 194397354 6479990 complement(1255881..1256330) 1 NC_011072.1 Tn5253 hypothetical protein 1256330 6479990 SPG_1290 Streptococcus pneumoniae G54 Tn5253 hypothetical protein YP_002037998.1 1255881 R 512566 CDS YP_002037999.1 194396841 6479986 complement(1256314..1257672) 1 NC_011072.1 identified by match to protein family HMM PF00145; match to protein family HMM TIGR00675; Tn5253 C-5 cytosine-specific DNA methylase 1257672 6479986 SPG_1291 Streptococcus pneumoniae G54 Tn5253 C-5 cytosine-specific DNA methylase YP_002037999.1 1256314 R 512566 CDS YP_002038000.1 194397418 6479410 complement(1257771..1258550) 1 NC_011072.1 identified by match to protein family HMM PF06970; Tn5253 hypothetical protein 1258550 6479410 SPG_1292 Streptococcus pneumoniae G54 Tn5253 hypothetical protein YP_002038000.1 1257771 R 512566 CDS YP_002038001.1 194397988 6479831 complement(1258547..1258720) 1 NC_011072.1 Tn5253 hypothetical protein 1258720 6479831 SPG_1293 Streptococcus pneumoniae G54 Tn5253 hypothetical protein YP_002038001.1 1258547 R 512566 CDS YP_002038002.1 194398613 6479605 complement(1258922..1259290) 1 NC_011072.1 present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulates GTPase activity of translation factors; 50S ribosomal protein L7/L12 1259290 rplL 6479605 rplL Streptococcus pneumoniae G54 50S ribosomal protein L7/L12 YP_002038002.1 1258922 R 512566 CDS YP_002038003.1 194397058 6478901 complement(1259366..1259866) 1 NC_011072.1 binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit; 50S ribosomal protein L10 1259866 rplJ 6478901 rplJ Streptococcus pneumoniae G54 50S ribosomal protein L10 YP_002038003.1 1259366 R 512566 CDS YP_002038004.1 194397682 6479705 complement(1260116..1261672) 1 NC_011072.1 identified by match to protein family HMM PF01979; match to protein family HMM PF07969; chlorohydrolase 1261672 6479705 SPG_1296 Streptococcus pneumoniae G54 chlorohydrolase YP_002038004.1 1260116 R 512566 CDS YP_002038005.1 194396730 6478741 complement(1261767..1263515) 1 NC_011072.1 identified by match to protein family HMM PF00005; match to protein family HMM PF00664; ABC transporter ATP-binding/permease 1263515 6478741 SPG_1298 Streptococcus pneumoniae G54 ABC transporter ATP-binding/permease YP_002038005.1 1261767 R 512566 CDS YP_002038006.1 194398299 6479639 complement(1263517..1265241) 1 NC_011072.1 identified by match to protein family HMM PF00005; match to protein family HMM PF00664; ABC transporter ATP-binding protein 1265241 6479639 SPG_1299 Streptococcus pneumoniae G54 ABC transporter ATP-binding protein YP_002038006.1 1263517 R 512566 CDS YP_002038007.1 194398406 6479455 complement(1265299..1266237) 1 NC_011072.1 identified by match to protein family HMM PF01625; match to protein family HMM PF01641; match to protein family HMM TIGR00357; match to protein family HMM TIGR00401; Peptide methionine sulfoxide reductase 1266237 6479455 SPG_1300 Streptococcus pneumoniae G54 Peptide methionine sulfoxide reductase YP_002038007.1 1265299 R 512566 CDS YP_002038008.1 194397963 6480767 complement(1266487..1267356) 1 NC_011072.1 catalyzes the formation of O-phospho-L-homoserine from L-homoserine in threonine biosynthesis from asparate; homoserine kinase 1267356 thrB 6480767 thrB Streptococcus pneumoniae G54 homoserine kinase YP_002038008.1 1266487 R 512566 CDS YP_002038009.1 194397726 6479363 complement(1267358..1268644) 1 NC_011072.1 catalyzes the formation of L-aspartate 4-semialdehyde from L-homoserine; homoserine dehydrogenase 1268644 metM 6479363 metM Streptococcus pneumoniae G54 homoserine dehydrogenase YP_002038009.1 1267358 R 512566 CDS YP_002038010.1 194397416 6480174 complement(1268795..1269532) 1 NC_011072.1 enables recognition and targeting of proteins for proteolysis, involved in negative regulation of competence; adaptor protein 1269532 6480174 SPG_1303 Streptococcus pneumoniae G54 adaptor protein YP_002038010.1 1268795 R 512566 CDS YP_002038011.1 194396791 6479829 complement(1269732..1270766) 1 NC_011072.1 hypothetical protein 1270766 6479829 SPG_1304 Streptococcus pneumoniae G54 hypothetical protein YP_002038011.1 1269732 R 512566 CDS YP_002038012.1 194398050 6480028 complement(1270795..1272228) 1 NC_011072.1 identified by glimmer; putative; hypothetical protein 1272228 6480028 SPG_1305 Streptococcus pneumoniae G54 hypothetical protein YP_002038012.1 1270795 R 512566 CDS YP_002038013.1 194397215 6479112 complement(1272244..1273230) 1 NC_011072.1 identified by match to protein family HMM PF00535; group 2 family glycosyl transferase 1273230 6479112 SPG_1306 Streptococcus pneumoniae G54 group 2 family glycosyl transferase YP_002038013.1 1272244 R 512566 CDS YP_002038014.1 194396746 6480281 complement(1273232..1274332) 1 NC_011072.1 identified by match to protein family HMM PF00534; group 1 family glycosyl transferase 1274332 6480281 SPG_1307 Streptococcus pneumoniae G54 group 1 family glycosyl transferase YP_002038014.1 1273232 R 512566 CDS YP_002038015.1 194398164 6480134 complement(1274325..1275170) 1 NC_011072.1 identified by match to protein family HMM PF04991; phosphotransferase LicD3 1275170 6480134 SPG_1308 Streptococcus pneumoniae G54 phosphotransferase LicD3 YP_002038015.1 1274325 R 512566 CDS YP_002038016.1 194397479 6480761 complement(1275449..1276723) 1 NC_011072.1 identified by match to protein family HMM PF03816; match to protein family HMM TIGR00350; LytR family transcriptional regulator 1276723 6480761 SPG_1309 Streptococcus pneumoniae G54 LytR family transcriptional regulator YP_002038016.1 1275449 R 512566 CDS YP_002038017.1 194398602 6480052 complement(1276720..1277568) 1 NC_011072.1 catalyzes the formation of phenylpyruvate from prephenate in phenylalanine biosynthesis; prephenate dehydratase 1277568 6480052 SPG_1310 Streptococcus pneumoniae G54 prephenate dehydratase YP_002038017.1 1276720 R 512566 CDS YP_002038018.1 194397091 6478942 complement(1277565..1278041) 1 NC_011072.1 identified by match to protein family HMM PF01202; shikimate kinase 1278041 6478942 SPG_1311 Streptococcus pneumoniae G54 shikimate kinase YP_002038018.1 1277565 R 512566 CDS YP_002038019.1 194397424 6479721 complement(1278034..1279317) 1 NC_011072.1 catalyzes the formation of 5-O-(1-carboxyvinyl)-3-phosphoshikimate from phosphoenolpyruvate and 3-phosphoshikimate in tryptophan biosynthesis; 3-phosphoshikimate 1-carboxyvinyltransferase 1279317 6479721 SPG_1312 Streptococcus pneumoniae G54 3-phosphoshikimate 1-carboxyvinyltransferase YP_002038019.1 1278034 R 512566 CDS YP_002038020.1 194398072 6480184 complement(1279409..1279747) 1 NC_011072.1 identified by match to protein family HMM PF06133; hypothetical protein 1279747 6480184 SPG_1313 Streptococcus pneumoniae G54 hypothetical protein YP_002038020.1 1279409 R 512566 CDS YP_002038021.1 194397877 6479437 complement(1279758..1280861) 1 NC_011072.1 catalyzes the formation of 4-hydroxyphenylpyruvate from prephenate; prephenate dehydrogenase 1280861 tyrA 6479437 tyrA Streptococcus pneumoniae G54 prephenate dehydrogenase YP_002038021.1 1279758 R 512566 CDS YP_002038022.1 194398485 6480237 complement(1280871..1282037) 1 NC_011072.1 catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis; chorismate synthase 1282037 aroC 6480237 aroC Streptococcus pneumoniae G54 chorismate synthase YP_002038022.1 1280871 R 512566 CDS YP_002038023.1 194396667 6480607 complement(1282047..1283114) 1 NC_011072.1 catalyzes the formation of 3-dehydroquinate from 3-deoxy-arabino-heptulonate 7-phosphate; functions in aromatic amino acid biosynthesis; 3-dehydroquinate synthase 1283114 aroB 6480607 aroB Streptococcus pneumoniae G54 3-dehydroquinate synthase YP_002038023.1 1282047 R 512566 CDS YP_002038024.1 194397256 6480260 complement(1283133..1283987) 1 NC_011072.1 AroE; catalyzes the conversion of shikimate to 3-dehydroshikimate; shikimate 5-dehydrogenase 1283987 aroE 6480260 aroE Streptococcus pneumoniae G54 shikimate 5-dehydrogenase YP_002038024.1 1283133 R 512566 CDS YP_002038025.1 194397964 6479874 complement(1283977..1284654) 1 NC_011072.1 catalyzes the dehydration of 3-dehydroquinate to form 3-dehydroshikimate in aromatic amino acid biosynthesis; 3-dehydroquinate dehydratase 1284654 aroD 6479874 aroD Streptococcus pneumoniae G54 3-dehydroquinate dehydratase YP_002038025.1 1283977 R 512566 CDS YP_002038026.1 194398591 6479364 complement(1284651..1285814) 1 NC_011072.1 hypothetical protein 1285814 6479364 SPG_1319 Streptococcus pneumoniae G54 hypothetical protein YP_002038026.1 1284651 R 512566 CDS YP_002038027.1 194397958 6479556 complement(1286498..1288132) 1 NC_011072.1 identified by glimmer; putative; hypothetical protein 1288132 6479556 SPG_1320 Streptococcus pneumoniae G54 hypothetical protein YP_002038027.1 1286498 R 512566 CDS YP_002038028.1 194398468 6479526 complement(1288113..1288862) 1 NC_011072.1 identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 1288862 6479526 SPG_1321 Streptococcus pneumoniae G54 ABC transporter ATP-binding protein YP_002038028.1 1288113 R 512566 CDS YP_002038029.1 194396694 6480788 1289041..1290495 1 NC_011072.1 converts 1,4-alpha-D-glucans to maltodextrin; cytoplasmic alpha-amylase 1290495 6480788 SPG_1322 Streptococcus pneumoniae G54 cytoplasmic alpha-amylase YP_002038029.1 1289041 D 512566 CDS YP_002038030.1 194397245 6479878 complement(1290585..1293203) 1 NC_011072.1 Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; alanyl-tRNA synthetase 1293203 alaS 6479878 alaS Streptococcus pneumoniae G54 alanyl-tRNA synthetase YP_002038030.1 1290585 R 512566 CDS YP_002038031.1 194398166 6480681 complement(1293225..1293710) 1 NC_011072.1 identified by match to protein family HMM PF04525; hypothetical protein 1293710 6480681 SPG_1324 Streptococcus pneumoniae G54 hypothetical protein YP_002038031.1 1293225 R 512566 CDS YP_002038032.1 194398708 6480374 complement(1294493..1295563) 1 NC_011072.1 Ware, D.; (2005) J.Microb. 43:398-405; identified by match to protein family HMM PF01547; spermidine/putrescine ABC transporter spermidine/putrescine-binding protein 1295563 potD 6480374 potD Streptococcus pneumoniae G54 spermidine/putrescine ABC transporter spermidine/putrescine-binding protein YP_002038032.1 1294493 R 512566 CDS YP_002038033.1 194397650 6479059 complement(1295560..1296333) 1 NC_011072.1 Ware, D.; (2005) J.Microb. 43:398-405; identified by match to protein family HMM PF00528; spermidine/putrescine ABC transporter permease 1296333 potC 6479059 potC Streptococcus pneumoniae G54 spermidine/putrescine ABC transporter permease YP_002038033.1 1295560 R 512566 CDS YP_002038034.1 194397147 6478816 complement(1296330..1297136) 1 NC_011072.1 Ware, D.; (2005) J.Microb. 43:398-405; identified by match to protein family HMM PF00528; spermidine/putrescine ABC transporter permease 1297136 potB 6478816 potB Streptococcus pneumoniae G54 spermidine/putrescine ABC transporter permease YP_002038034.1 1296330 R 512566 CDS YP_002038035.1 194398453 6480798 complement(1297117..1298274) 1 NC_011072.1 Ware, D.; (2005) J.Microb. 43:398-405; identified by match to protein family HMM PF00005; match to protein family HMM PF08402; spermidine/putrescine ABC transporter ATP-binding protein 1298274 potA 6480798 potA Streptococcus pneumoniae G54 spermidine/putrescine ABC transporter ATP-binding protein YP_002038035.1 1297117 R 512566 CDS YP_002038036.1 194398159 6480432 complement(1298332..1299282) 1 NC_011072.1 catalyzes the reduction of UDP-N-acetylglucosamine enolpyruvate to form UDP-N-acetylmuramate in peptidoglycan biosynthesis; UDP-N-acetylenolpyruvoylglucosamine reductase 1299282 murB 6480432 murB Streptococcus pneumoniae G54 UDP-N-acetylenolpyruvoylglucosamine reductase YP_002038036.1 1298332 R 512566 CDS YP_002038037.1 194397012 6480595 complement(1299394..1299903) 1 NC_011072.1 contains potential frameshift; hypothetical protein 1299903 6480595 SPG_1330 Streptococcus pneumoniae G54 hypothetical protein YP_002038037.1 1299394 R 512566 CDS YP_002038038.1 194397189 6480230 complement(1299956..1300147) 1 NC_011072.1 contains potential frameshift; hypothetical protein 1300147 6480230 SPG_1331 Streptococcus pneumoniae G54 hypothetical protein YP_002038038.1 1299956 R 512566 CDS YP_002038039.1 194397980 6478734 complement(1300157..1300888) 1 NC_011072.1 identified by match to protein family HMM PF03306; match to protein family HMM TIGR01252; alpha-acetolactate decarboxylase 1300888 6478734 SPG_1332 Streptococcus pneumoniae G54 alpha-acetolactate decarboxylase YP_002038039.1 1300157 R 512566 CDS YP_002038040.1 194398700 6479314 1301030..1301572 1 NC_011072.1 contains potential frameshift; identified by match to protein family HMM PF00392; GntR family transcriptional regulator 1301572 6479314 SPG_1333 Streptococcus pneumoniae G54 GntR family transcriptional regulator YP_002038040.1 1301030 D 512566 CDS YP_002038041.1 194397195 6479132 1301569..1302303 1 NC_011072.1 contains potential frameshift; GntR family transcriptional regulator 1302303 6479132 SPG_1334 Streptococcus pneumoniae G54 GntR family transcriptional regulator YP_002038041.1 1301569 D 512566 CDS YP_002038042.1 194397488 6479771 complement(1302323..1303138) 1 NC_011072.1 identified by match to protein family HMM PF00497; ABC transporter amino acid-binding protein 1303138 6479771 SPG_1335 Streptococcus pneumoniae G54 ABC transporter amino acid-binding protein YP_002038042.1 1302323 R 512566 CDS YP_002038043.1 194398248 6480638 complement(1303295..1303948) 1 NC_011072.1 identified by match to protein family HMM PF01895; match to protein family HMM TIGR02135; phosphate transport system regulatory protein PhoU 1303948 phoU 6480638 phoU Streptococcus pneumoniae G54 phosphate transport system regulatory protein PhoU YP_002038043.1 1303295 R 512566 CDS YP_002038044.1 194398371 6479046 complement(1303960..1304718) 1 NC_011072.1 ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation; phosphate transporter ATP-binding protein 1304718 6479046 SPG_1337 Streptococcus pneumoniae G54 phosphate transporter ATP-binding protein YP_002038044.1 1303960 R 512566 CDS YP_002038045.1 194397671 6479168 complement(1304731..1305534) 1 NC_011072.1 ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation; phosphate transporter ATP-binding protein 1305534 6479168 SPG_1338 Streptococcus pneumoniae G54 phosphate transporter ATP-binding protein YP_002038045.1 1304731 R 512566 CDS YP_002038046.1 194397435 6479570 complement(1305545..1306429) 1 NC_011072.1 identified by match to protein family HMM PF00528; match to protein family HMM TIGR00974; phosphate ABC transporter permease 1306429 6479570 SPG_1339 Streptococcus pneumoniae G54 phosphate ABC transporter permease YP_002038046.1 1305545 R 512566 CDS YP_002038047.1 194396785 6480727 complement(1306419..1307336) 1 NC_011072.1 identified by match to protein family HMM PF00528; match to protein family HMM TIGR02138; phosphate ABC transporter permease 1307336 6480727 SPG_1340 Streptococcus pneumoniae G54 phosphate ABC transporter permease YP_002038047.1 1306419 R 512566 CDS YP_002038048.1 194397126 6479668 complement(1307336..1308214) 1 NC_011072.1 identified by match to protein family HMM PF01547; match to protein family HMM TIGR02136; phosphate binding protein 1308214 6479668 SPG_1341 Streptococcus pneumoniae G54 phosphate binding protein YP_002038048.1 1307336 R 512566 CDS YP_002038049.1 194397460 6480529 1308444..1308557 1 NC_011072.1 hypothetical protein 1308557 6480529 SPG_1342 Streptococcus pneumoniae G54 hypothetical protein YP_002038049.1 1308444 D 512566 CDS YP_002038050.1 194397739 6480267 complement(1308788..1310092) 1 NC_011072.1 identified by match to protein family HMM PF01189; NOL1/NOP2/sun family protein 1310092 6480267 SPG_1343 Streptococcus pneumoniae G54 NOL1/NOP2/sun family protein YP_002038050.1 1308788 R 512566 CDS YP_002038051.1 194398688 6480132 complement(1310093..1310866) 1 NC_011072.1 identified by match to protein family HMM PF00459; inositol monophosphatase family protein 1310866 6480132 SPG_1344 Streptococcus pneumoniae G54 inositol monophosphatase family protein YP_002038051.1 1310093 R 512566 CDS YP_002038052.1 194396796 6478999 complement(1310856..1311134) 1 NC_011072.1 identified by glimmer; putative; hypothetical protein 1311134 6478999 SPG_1345 Streptococcus pneumoniae G54 hypothetical protein YP_002038052.1 1310856 R 512566 CDS YP_002038053.1 194397210 6479337 complement(1311134..1311535) 1 NC_011072.1 the anti-alpha factor Spx interacts with RNA polymerase alpha subunit C-terminal domain in a region that interacts with the sigma 70 subunit and may interfere with activation of promoters; in Bacillus subtilis this protein is a substrate for ClpXP protease; blocks transcription of the competence regulatory gene encoded by the srf operon; regulates a number of genes involved in thiol homeostasis including trxA and trxB; monomeric member of ArsC family of proteins; does not bind DNA; contains a disulfide bond between C10 and C13 which may sense disulfide stress; transcriptional regulator Spx 1311535 spxA 6479337 spxA Streptococcus pneumoniae G54 transcriptional regulator Spx YP_002038053.1 1311134 R 512566 CDS YP_002038054.1 194397752 6480578 complement(1311745..1312362) 1 NC_011072.1 identified by glimmer; putative; hypothetical protein 1312362 6480578 SPG_1347 Streptococcus pneumoniae G54 hypothetical protein YP_002038054.1 1311745 R 512566 CDS YP_002038055.1 194398493 6480252 complement(1312352..1313125) 1 NC_011072.1 identified by match to protein family HMM PF00702; match to protein family HMM TIGR01457; match to protein family HMM TIGR01460; haloacid dehalogenase-like hydrolase 1313125 6480252 SPG_1348 Streptococcus pneumoniae G54 haloacid dehalogenase-like hydrolase YP_002038055.1 1312352 R 512566 CDS YP_002038056.1 194396832 6480512 complement(1313136..1313873) 1 NC_011072.1 identified by match to protein family HMM PF01643; acyl-ACP thioesterase 1313873 6480512 SPG_1349 Streptococcus pneumoniae G54 acyl-ACP thioesterase YP_002038056.1 1313136 R 512566 CDS YP_002038057.1 194397558 6480473 complement(1313878..1315008) 1 NC_011072.1 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III; coproporphyrinogen III oxidase 1315008 6480473 SPG_1350 Streptococcus pneumoniae G54 coproporphyrinogen III oxidase YP_002038057.1 1313878 R 512566 CDS YP_002038058.1 194397886 6478800 complement(1315092..1315481) 1 NC_011072.1 hypothetical protein 1315481 6478800 SPG_1351 Streptococcus pneumoniae G54 hypothetical protein YP_002038058.1 1315092 R 512566 CDS YP_002038059.1 194398462 6480814 complement(1315497..1315880) 1 NC_011072.1 identified by match to protein family HMM PF06103; hypothetical protein 1315880 6480814 SPG_1352 Streptococcus pneumoniae G54 hypothetical protein YP_002038059.1 1315497 R 512566 CDS YP_002038060.1 194396762 6480775 complement(1315881..1316669) 1 NC_011072.1 transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein; prolipoprotein diacylglyceryl transferase 1316669 6480775 SPG_1353 Streptococcus pneumoniae G54 prolipoprotein diacylglyceryl transferase YP_002038060.1 1315881 R 512566 CDS YP_002038061.1 194397109 6480165 complement(1316662..1317597) 1 NC_011072.1 catalyzes the phosphorylation of the phosphocarrier protein HPr of the bacterial phosphotransferase system; HPr kinase/phosphorylase 1317597 hprK 6480165 hprK Streptococcus pneumoniae G54 HPr kinase/phosphorylase YP_002038061.1 1316662 R 512566 CDS YP_002038062.1 194397316 6480294 complement(1317727..1317903) 1 NC_011072.1 a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA; 30S ribosomal protein S21 1317903 rpsU 6480294 rpsU Streptococcus pneumoniae G54 30S ribosomal protein S21 YP_002038062.1 1317727 R 512566 CDS YP_002038063.1 194398073 6479779 complement(1318043..1318750) 1 NC_011072.1 identified by similarity to RF:NP_358865.1; match to protein family HMM PF01182; glucosamine-6-phosphate deaminase 1318750 nagB 6479779 nagB Streptococcus pneumoniae G54 glucosamine-6-phosphate deaminase YP_002038063.1 1318043 R 512566 CDS YP_002038064.1 194397598 6479438 1318901..1319929 1 NC_011072.1 Synthesizes oQ from preQ1 in a single S-adenosylmethionine-requiring step; S-adenosylmethionine:tRNA ribosyltransferase-isomerase 1319929 queA 6479438 queA Streptococcus pneumoniae G54 S-adenosylmethionine:tRNA ribosyltransferase-isomerase YP_002038064.1 1318901 D 512566 CDS YP_002038065.1 194397785 6478796 complement(1320590..1320979) 1 NC_011072.1 identified by match to protein family HMM PF01473; choline binding protein 1320979 6478796 SPG_1358 Streptococcus pneumoniae G54 choline binding protein YP_002038065.1 1320590 R 512566 CDS YP_002038066.1 194398328 6479965 complement(1322440..1322991) 1 NC_011072.1 identified by match to protein family HMM PF00583; GNAT family acetyltransferase 1322991 6479965 SPG_1359 Streptococcus pneumoniae G54 GNAT family acetyltransferase YP_002038066.1 1322440 R 512566 CDS YP_002038067.1 194398399 6479289 complement(1323341..1324165) 1 NC_011072.1 catalyzes the formation of nicotinamide adenine dinucleotide (NAD) from nicotinic acid adenine dinucleotide (NAAD) using either ammonia or glutamine as the amide donor and ATP; ammonia-utilizing enzymes include the ones from Bacillus and Escherichia coli while glutamine-utilizing enzymes include the Mycobacterial one; forms homodimers; NAD synthetase 1324165 nadE 6479289 nadE Streptococcus pneumoniae G54 NAD synthetase YP_002038067.1 1323341 R 512566 CDS YP_002038068.1 194396973 6478900 complement(1324162..1325622) 1 NC_011072.1 catalyzes the formation of 5-phospho-alpha-D-ribose 1-diphosphate and nicotinate from nicotinate D-ribonucleotide and diphosphate; nicotinate phosphoribosyltransferase 1325622 pncB 6478900 pncB Streptococcus pneumoniae G54 nicotinate phosphoribosyltransferase YP_002038068.1 1324162 R 512566 CDS YP_002038069.1 194397709 6480166 complement(1325738..1326226) 1 NC_011072.1 hypothetical protein 1326226 6480166 SPG_1362 Streptococcus pneumoniae G54 hypothetical protein YP_002038069.1 1325738 R 512566 CDS YP_002038070.1 194398183 6480058 complement(1326216..1326425) 1 NC_011072.1 identified by match to protein family HMM PF01381; hypothetical protein 1326425 6480058 SPG_1363 Streptococcus pneumoniae G54 hypothetical protein YP_002038070.1 1326216 R 512566 CDS YP_002038071.1 194397831 6480547 complement(1326810..1327538) 1 NC_011072.1 identified by glimmer; putative; hypothetical protein 1327538 6480547 SPG_1364 Streptococcus pneumoniae G54 hypothetical protein YP_002038071.1 1326810 R 512566 CDS YP_002038072.1 194398316 6480460 complement(1327554..1327814) 1 NC_011072.1 contains potential frameshift; ABC transporter ATP-binding protein 1327814 6480460 SPG_1365 Streptococcus pneumoniae G54 ABC transporter ATP-binding protein YP_002038072.1 1327554 R 512566 CDS YP_002038073.1 194396677 6479039 complement(1327900..1328274) 1 NC_011072.1 contains potential frameshift; ABC transporter ATP-binding protein 1328274 6479039 SPG_1366 Streptococcus pneumoniae G54 ABC transporter ATP-binding protein YP_002038073.1 1327900 R 512566 CDS YP_002038074.1 194398510 6479743 complement(1328782..1329507) 1 NC_011072.1 identified by match to protein family HMM PF01136; protease 1329507 6479743 SPG_1367 Streptococcus pneumoniae G54 protease YP_002038074.1 1328782 R 512566 CDS YP_002038075.1 194396652 6480592 1329693..1329842 1 NC_011072.1 hypothetical protein 1329842 6480592 SPG_1368 Streptococcus pneumoniae G54 hypothetical protein YP_002038075.1 1329693 D 512566 CDS YP_002038076.1 194397527 6479691 complement(1330097..1331383) 1 NC_011072.1 identified by match to protein family HMM PF01136; protease 1331383 6479691 SPG_1369 Streptococcus pneumoniae G54 protease YP_002038076.1 1330097 R 512566 CDS YP_002038077.1 194397292 6479085 1332007..1332189 1 NC_011072.1 identified by similarity to GB:AAL00089.1; type II restriction endonuclease 1332189 6479085 SPG_1370 Streptococcus pneumoniae G54 type II restriction endonuclease YP_002038077.1 1332007 D 512566 CDS YP_002038078.1 194397912 6478695 1332373..1332561 1 NC_011072.1 type II restriction endonuclease 1332561 6478695 SPG_1371 Streptococcus pneumoniae G54 type II restriction endonuclease YP_002038078.1 1332373 D 512566 CDS YP_002038079.1 194398500 6479372 1332558..1333748 1 NC_011072.1 identified by match to protein family HMM PF01555; type II DNA modification methyltransferase 1333748 6479372 SPG_1372 Streptococcus pneumoniae G54 type II DNA modification methyltransferase YP_002038079.1 1332558 D 512566 CDS YP_002038080.1 194397166 6480659 complement(1333824..1335386) 1 NC_011072.1 contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway; GMP synthase 1335386 guaA 6480659 guaA Streptococcus pneumoniae G54 GMP synthase YP_002038080.1 1333824 R 512566 CDS YP_002038081.1 194396686 6479354 1335528..1336226 1 NC_011072.1 identified by match to protein family HMM PF00392; match to protein family HMM PF07702; GntR family transcriptional regulator 1336226 6479354 SPG_1374 Streptococcus pneumoniae G54 GntR family transcriptional regulator YP_002038081.1 1335528 D 512566 CDS YP_002038082.1 194398114 6479801 complement(1336269..1337165) 1 NC_011072.1 identified by match to protein family HMM PF00892; hypothetical protein 1337165 6479801 SPG_1375 Streptococcus pneumoniae G54 hypothetical protein YP_002038082.1 1336269 R 512566 CDS YP_002038083.1 194398581 6480644 complement(1337174..1338109) 1 NC_011072.1 identified by glimmer; putative; hypothetical protein 1338109 6480644 SPG_1376 Streptococcus pneumoniae G54 hypothetical protein YP_002038083.1 1337174 R 512566 CDS YP_002038084.1 194397640 6478714 complement(1338106..1338831) 1 NC_011072.1 C3-degrading proteinase 1338831 6478714 SPG_1377 Streptococcus pneumoniae G54 C3-degrading proteinase YP_002038084.1 1338106 R 512566 CDS YP_002038085.1 194396978 6478738 complement(1338915..1339550) 1 NC_011072.1 identified by match to protein family HMM PF00657; hypothetical protein 1339550 6478738 SPG_1378 Streptococcus pneumoniae G54 hypothetical protein YP_002038085.1 1338915 R 512566 CDS YP_002038086.1 194397765 6479664 complement(1339552..1340379) 1 NC_011072.1 identified by match to protein family HMM PF00702; match to protein family HMM PF05116; match to protein family HMM PF08282; match to protein family HMM TIGR00099; match to protein family HMM TIGR01484; Cof family protein 1340379 6479664 SPG_1379 Streptococcus pneumoniae G54 Cof family protein YP_002038086.1 1339552 R 512566 CDS YP_002038087.1 194398380 6480216 complement(1340483..1340737) 1 NC_011072.1 hypothetical protein 1340737 6480216 SPG_1380 Streptococcus pneumoniae G54 hypothetical protein YP_002038087.1 1340483 R 512566 CDS YP_002038088.1 194397366 6478743 complement(1340738..1341454) 1 NC_011072.1 identified by glimmer; putative; hypothetical protein 1341454 6478743 SPG_1381 Streptococcus pneumoniae G54 hypothetical protein YP_002038088.1 1340738 R 512566 CDS YP_002038089.1 194396894 6480157 1341967..1342578 1 NC_011072.1 cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+); peptide deformylase 1342578 def 6480157 def Streptococcus pneumoniae G54 peptide deformylase YP_002038089.1 1341967 D 512566 CDS YP_002038090.1 194397072 6479147 1342623..1343351 1 NC_011072.1 identified by match to protein family HMM PF00588; match to protein family HMM PF08032; match to protein family HMM TIGR00186; TrmH family RNA methyltransferase 1343351 6479147 SPG_1383 Streptococcus pneumoniae G54 TrmH family RNA methyltransferase YP_002038090.1 1342623 D 512566 CDS YP_002038091.1 194398705 6479865 complement(1343390..1344301) 1 NC_011072.1 identified by match to protein family HMM PF00070; match to protein family HMM PF01134; match to protein family HMM PF01266; match to protein family HMM PF03486; match to protein family HMM PF07992; match to protein family HMM TIGR01292; thioredoxin reductase 1344301 trxB 6479865 trxB Streptococcus pneumoniae G54 thioredoxin reductase YP_002038091.1 1343390 R 512566 CDS YP_002038092.1 194398254 6479444 complement(1344367..1344591) 1 NC_011072.1 hypothetical protein 1344591 6479444 SPG_1385 Streptococcus pneumoniae G54 hypothetical protein YP_002038092.1 1344367 R 512566 CDS YP_002038093.1 194397248 6479281 complement(1344669..1345412) 1 NC_011072.1 identified by match to protein family HMM PF00005; amino acid ABC transporter ATP-binding protein 1345412 6479281 SPG_1386 Streptococcus pneumoniae G54 amino acid ABC transporter ATP-binding protein YP_002038093.1 1344669 R 512566 CDS YP_002038094.1 194398452 6480378 complement(1345412..1346212) 1 NC_011072.1 identified by match to protein family HMM PF00528; match to protein family HMM TIGR01726; amino acid ABC transporter permease 1346212 6480378 SPG_1387 Streptococcus pneumoniae G54 amino acid ABC transporter permease YP_002038094.1 1345412 R 512566 CDS YP_002038095.1 194397502 6480431 complement(1346370..1346726) 1 NC_011072.1 identified by match to protein family HMM PF03960; match to protein family HMM TIGR01617; hypothetical protein 1346726 6480431 SPG_1388 Streptococcus pneumoniae G54 hypothetical protein YP_002038095.1 1346370 R 512566 CDS YP_002038096.1 194397010 6479264 complement(1346739..1347251) 1 NC_011072.1 identified by match to protein family HMM PF01035; match to protein family HMM TIGR00589; methylated-DNA-[protein]-cysteine S-methyltransferase 1347251 6479264 SPG_1389 Streptococcus pneumoniae G54 methylated-DNA-[protein]-cysteine S-methyltransferase YP_002038096.1 1346739 R 512566 CDS YP_002038097.1 194398553 6480683 complement(1347251..1347745) 1 NC_011072.1 identified by match to protein family HMM PF00583; GNAT family acetyltransferase 1347745 6480683 SPG_1390 Streptococcus pneumoniae G54 GNAT family acetyltransferase YP_002038097.1 1347251 R 512566 CDS YP_002038098.1 194396670 6480086 1347880..1348326 1 NC_011072.1 identified by match to protein family HMM PF08876; hypothetical protein 1348326 6480086 SPG_1391 Streptococcus pneumoniae G54 hypothetical protein YP_002038098.1 1347880 D 512566 CDS YP_002038099.1 194397266 6479685 1348323..1348970 1 NC_011072.1 identified by match to protein family HMM PF03006; match to protein family HMM TIGR01065; hemolysin 1348970 6479685 SPG_1392 Streptococcus pneumoniae G54 hemolysin YP_002038099.1 1348323 D 512566 CDS YP_002038100.1 194398369 6479585 complement(1348991..1349572) 1 NC_011072.1 with PdxST is involved in the biosynthesis of pyridoxal 5'-phosphate; PdxT catalyzes the hydrolysis of glutamine to glutamate and ammonia; PdxS utilizes the ammonia to synthesize pyridoxal 5'-phosphate; glutamine amidotransferase subunit PdxT 1349572 pdxT 6479585 pdxT Streptococcus pneumoniae G54 glutamine amidotransferase subunit PdxT YP_002038100.1 1348991 R 512566 CDS YP_002038101.1 194396783 6479602 complement(1349573..1350448) 1 NC_011072.1 with PdxT forms pyridoxal 5'-phosphate from glutamine, either ribose 5-phosphate or ribulose 5-phosphate, and either glyceraldehyde 3-phosphate or dihydroxyacetone phosphate; pyridoxal biosynthesis lyase PdxS 1350448 pdxS 6479602 pdxS Streptococcus pneumoniae G54 pyridoxal biosynthesis lyase PdxS YP_002038101.1 1349573 R 512566 CDS YP_002038102.1 194397445 6479708 complement(1350600..1351355) 1 NC_011072.1 contains potential frameshift; identified by match to protein family HMM PF02852; NADH oxidase 1351355 6479708 SPG_1395 Streptococcus pneumoniae G54 NADH oxidase YP_002038102.1 1350600 R 512566 CDS YP_002038103.1 194397513 6480350 complement(1351405..1351980) 1 NC_011072.1 contains potential frameshift; identified by match to protein family HMM PF07992; NADH oxidase 1351980 6480350 SPG_1396 Streptococcus pneumoniae G54 NADH oxidase YP_002038103.1 1351405 R 512566 CDS YP_002038104.1 194397442 6479379 1352122..1352277 1 NC_011072.1 identified by glimmer; putative; hypothetical protein 1352277 6479379 SPG_1397 Streptococcus pneumoniae G54 hypothetical protein YP_002038104.1 1352122 D 512566 CDS YP_002038105.1 194396816 6480811 1352274..1353197 1 NC_011072.1 identified by match to protein family HMM PF02424; thiamine biosynthesis protein ApbE 1353197 6480811 SPG_1398 Streptococcus pneumoniae G54 thiamine biosynthesis protein ApbE YP_002038105.1 1352274 D 512566 CDS YP_002038106.1 194397998 6478982 1353257..1353862 1 NC_011072.1 identified by match to protein family HMM PF03358; oxidoreductase 1353862 6478982 SPG_1399 Streptococcus pneumoniae G54 oxidoreductase YP_002038106.1 1353257 D 512566 CDS YP_002038107.1 194397198 6479615 1353881..1355125 1 NC_011072.1 identified by match to protein family HMM PF03358; oxidoreductase 1355125 6479615 SPG_1400 Streptococcus pneumoniae G54 oxidoreductase YP_002038107.1 1353881 D 512566 CDS YP_002038108.1 194398161 6480396 complement(1355242..1355499) 1 NC_011072.1 identified by glimmer; putative; hypothetical protein 1355499 6480396 SPG_1401 Streptococcus pneumoniae G54 hypothetical protein YP_002038108.1 1355242 R 512566 CDS YP_002038109.1 194398749 6480805 complement(1355541..1357577) 1 NC_011072.1 glycine--tRNA ligase beta chain; glyS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; glycyl-tRNA synthetase subunit beta 1357577 glyS 6480805 glyS Streptococcus pneumoniae G54 glycyl-tRNA synthetase subunit beta YP_002038109.1 1355541 R 512566 CDS YP_002038110.1 194396970 6478764 complement(1357837..1358754) 1 NC_011072.1 glycine--tRNA ligase alpha chain; GlyRS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; glycyl-tRNA synthetase subunit alpha 1358754 glyQ 6478764 glyQ Streptococcus pneumoniae G54 glycyl-tRNA synthetase subunit alpha YP_002038110.1 1357837 R 512566 CDS YP_002038111.1 194398414 6479759 complement(1358948..1359709) 1 NC_011072.1 identified by glimmer; putative; hypothetical protein 1359709 6479759 SPG_1404 Streptococcus pneumoniae G54 hypothetical protein YP_002038111.1 1358948 R 512566 CDS YP_002038112.1 194398597 6480809 complement(1359982..1360824) 1 NC_011072.1 identified by match to protein family HMM PF00248; aldo/keto reductase family oxidoreductase 1360824 6480809 SPG_1405 Streptococcus pneumoniae G54 aldo/keto reductase family oxidoreductase YP_002038112.1 1359982 R 512566 CDS YP_002038113.1 194397649 6479325 complement(1361080..1362417) 1 NC_011072.1 Vollmer, W. (2000)J.Biol. Chem. 275, 20496-20501.; identified by similarity to GB:CAB96552.1; match to protein family HMM PF01522; peptidoglycan GlcNAc deacetylase PgdA 1362417 pgdA 6479325 pgdA Streptococcus pneumoniae G54 peptidoglycan GlcNAc deacetylase PgdA YP_002038113.1 1361080 R 512566 CDS YP_002038114.1 194397820 6478845 complement(1362853..1363083) 1 NC_011072.1 hypothetical protein 1363083 6478845 SPG_1407 Streptococcus pneumoniae G54 hypothetical protein YP_002038114.1 1362853 R 512566 CDS YP_002038115.1 194398282 6480819 1363316..1364293 1 NC_011072.1 identified by match to protein family HMM PF01118; match to protein family HMM PF01408; oxidoreductase family protein 1364293 6480819 SPG_1408 Streptococcus pneumoniae G54 oxidoreductase family protein YP_002038115.1 1363316 D 512566 CDS YP_002038116.1 194398275 6479319 1364290..1365372 1 NC_011072.1 identified by match to protein family HMM PF00270; match to protein family HMM PF00271; hypothetical protein 1365372 6479319 SPG_1409 Streptococcus pneumoniae G54 hypothetical protein YP_002038116.1 1364290 D 512566 CDS YP_002038117.1 194398736 6478657 complement(1365531..1365944) 1 NC_011072.1 IS630-SpnII transposase 1365944 6478657 SPG_1410 Streptococcus pneumoniae G54 IS630-SpnII transposase YP_002038117.1 1365531 R 512566 CDS YP_002038118.1 194398181 6479114 complement(1365976..1366380) 1 NC_011072.1 IS630-SpnII transposase 1366380 6479114 SPG_1411 Streptococcus pneumoniae G54 IS630-SpnII transposase YP_002038118.1 1365976 R 512566 CDS YP_002038119.1 194397593 6480545 complement(1366353..1366484) 1 NC_011072.1 hypothetical protein 1366484 6480545 SPG_1412 Streptococcus pneumoniae G54 hypothetical protein YP_002038119.1 1366353 R 512566 CDS YP_002038120.1 194396810 6478705 complement(1366868..1368064) 1 NC_011072.1 EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu; elongation factor Tu 1368064 6478705 SPG_1413 Streptococcus pneumoniae G54 elongation factor Tu YP_002038120.1 1366868 R 512566 CDS YP_002038121.1 194398547 6479895 complement(1368407..1368529) 1 NC_011072.1 identified by glimmer; putative; hypothetical protein 1368529 6479895 SPG_1414 Streptococcus pneumoniae G54 hypothetical protein YP_002038121.1 1368407 R 512566 CDS YP_002038122.1 194397772 6480673 complement(1368975..1369844) 1 NC_011072.1 identified by match to protein family HMM PF00230; glycerol uptake facilitator protein 1369844 6480673 SPG_1415 Streptococcus pneumoniae G54 glycerol uptake facilitator protein YP_002038122.1 1368975 R 512566 CDS YP_002038123.1 194397250 6480027 complement(1370057..1370587) 1 NC_011072.1 identified by match to protein family HMM PF00746; match to protein family HMM PF06458; match to protein family HMM TIGR01167; cell wall surface anchor family protein 1370587 6480027 SPG_1416 Streptococcus pneumoniae G54 cell wall surface anchor family protein YP_002038123.1 1370057 R 512566 CDS YP_002038124.1 194397632 6479790 complement(1370545..1371651) 1 NC_011072.1 hypothetical protein 1371651 6479790 SPG_1417 Streptococcus pneumoniae G54 hypothetical protein YP_002038124.1 1370545 R 512566 CDS YP_002038125.1 194397167 6478863 complement(1371762..1371908) 1 NC_011072.1 hypothetical protein 1371908 6478863 SPG_1418 Streptococcus pneumoniae G54 hypothetical protein YP_002038125.1 1371762 R 512566 CDS YP_002038126.1 194398287 6479355 complement(1372374..1372907) 1 NC_011072.1 IS630-Spn1 transposase 1372907 6479355 SPG_1419 Streptococcus pneumoniae G54 IS630-Spn1 transposase YP_002038126.1 1372374 R 512566 CDS YP_002038127.1 194397833 6479009 complement(1372894..1373109) 1 NC_011072.1 transposase 1373109 6479009 SPG_1420 Streptococcus pneumoniae G54 transposase YP_002038127.1 1372894 R 512566 CDS YP_002038128.1 194397272 6480668 1373454..1375172 1 NC_011072.1 identified by match to protein family HMM PF00408; match to protein family HMM PF02878; match to protein family HMM PF02879; match to protein family HMM PF02880; phosphoglucomutase/phosphomannomutase family protein 1375172 6480668 SPG_1421 Streptococcus pneumoniae G54 phosphoglucomutase/phosphomannomutase family protein YP_002038128.1 1373454 D 512566 CDS YP_002038129.1 194396668 6478767 1375283..1375630 1 NC_011072.1 identified by match to protein family HMM TIGR01295; bacteriocin transport accessory protein 1375630 6478767 SPG_1422 Streptococcus pneumoniae G54 bacteriocin transport accessory protein YP_002038129.1 1375283 D 512566 CDS YP_002038130.1 194397294 6480142 complement(1375908..1376744) 1 NC_011072.1 identified by match to protein family HMM PF00497; ABC transporter substrate-binding protein 1376744 6480142 SPG_1423 Streptococcus pneumoniae G54 ABC transporter substrate-binding protein YP_002038130.1 1375908 R 512566 CDS YP_002038131.1 194396690 6478919 complement(1376757..1377386) 1 NC_011072.1 identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 1377386 6478919 SPG_1424 Streptococcus pneumoniae G54 ABC transporter ATP-binding protein YP_002038131.1 1376757 R 512566 CDS YP_002038132.1 194398715 6479915 complement(1377396..1378037) 1 NC_011072.1 identified by match to protein family HMM PF00528; match to protein family HMM TIGR01726; ABC transporter permease 1378037 6479915 SPG_1425 Streptococcus pneumoniae G54 ABC transporter permease YP_002038132.1 1377396 R 512566 CDS YP_002038133.1 194398128 6478805 complement(1378183..1379328) 1 NC_011072.1 identified by match to protein family HMM PF00515; match to protein family HMM PF07719; hypothetical protein 1379328 6478805 SPG_1426 Streptococcus pneumoniae G54 hypothetical protein YP_002038133.1 1378183 R 512566 CDS YP_002038134.1 194397569 6480651 complement(1379403..1380569) 1 NC_011072.1 identified by match to protein family HMM PF01594; hypothetical protein 1380569 6480651 SPG_1427 Streptococcus pneumoniae G54 hypothetical protein YP_002038134.1 1379403 R 512566 CDS YP_002038135.1 194396925 6479305 1380713..1381726 1 NC_011072.1 hypothetical protein 1381726 6479305 SPG_1428 Streptococcus pneumoniae G54 hypothetical protein YP_002038135.1 1380713 D 512566 CDS YP_002038136.1 194396944 6479741 complement(1381771..1382190) 1 NC_011072.1 part of catalytic core of ATP synthase; alpha(3)beta(3)gamma(1)delta(1)epsilon(1); involved in producing ATP from ADP in the presence of the proton motive force across the membrane; F0F1 ATP synthase subunit epsilon 1382190 atpC 6479741 atpC Streptococcus pneumoniae G54 F0F1 ATP synthase subunit epsilon YP_002038136.1 1381771 R 512566 CDS YP_002038137.1 194397468 6479753 complement(1382201..1383607) 1 NC_011072.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit; F0F1 ATP synthase subunit beta 1383607 6479753 SPG_1430 Streptococcus pneumoniae G54 F0F1 ATP synthase subunit beta YP_002038137.1 1382201 R 512566 CDS YP_002038138.1 194397035 6480022 complement(1383693..1383974) 1 NC_011072.1 contains potential frameshift; Martin-Galiano, A.J. (2001) Mol.Micr. 41(6), 1327-1338; identified by match to protein family HMM PF00231; ATP synthase F1 subunit gamma 1383974 6480022 SPG_1431 Streptococcus pneumoniae G54 ATP synthase F1 subunit gamma YP_002038138.1 1383693 R 512566 CDS YP_002038139.1 194397515 6479847 complement(1383961..1384572) 1 NC_011072.1 contains potential frameshift; Martin-Galiano, A.J. (2001) Mol.Micr. 41(6), 1327-1338; identified by match to protein family HMM PF00231; ATP synthase F1 subunit gamma 1384572 6479847 SPG_1432 Streptococcus pneumoniae G54 ATP synthase F1 subunit gamma YP_002038139.1 1383961 R 512566 CDS YP_002038140.1 194398243 6479401 complement(1384588..1386093) 1 NC_011072.1 produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit; F0F1 ATP synthase subunit alpha 1386093 6479401 SPG_1433 Streptococcus pneumoniae G54 F0F1 ATP synthase subunit alpha YP_002038140.1 1384588 R 512566 CDS YP_002038141.1 194398696 6479217 complement(1386108..1386644) 1 NC_011072.1 Produces ATP from ADP in the presence of a proton gradient across the membrane; the delta subunit is part of the catalytic core of the ATP synthase complex; F0F1 ATP synthase subunit delta 1386644 6479217 SPG_1434 Streptococcus pneumoniae G54 F0F1 ATP synthase subunit delta YP_002038141.1 1386108 R 512566 CDS YP_002038142.1 194396745 6479109 complement(1386644..1387138) 1 NC_011072.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit B is part of the membrane proton channel.; F0F1 ATP synthase subunit B 1387138 atpB 6479109 atpB Streptococcus pneumoniae G54 F0F1 ATP synthase subunit B YP_002038142.1 1386644 R 512566 CDS YP_002038143.1 194397229 6479738 complement(1387152..1387868) 1 NC_011072.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0; F0F1 ATP synthase subunit A 1387868 atpA 6479738 atpA Streptococcus pneumoniae G54 F0F1 ATP synthase subunit A YP_002038143.1 1387152 R 512566 CDS YP_002038144.1 194397956 6479910 complement(1387903..1388103) 1 NC_011072.1 produces ATP from ADP in the presence of a proton gradient across the membrane; subunit C is part of the membrane proton channel F0; F0F1 ATP synthase subunit C 1388103 atpC 6479910 atpC Streptococcus pneumoniae G54 F0F1 ATP synthase subunit C YP_002038144.1 1387903 R 512566 CDS YP_002038145.1 194397020 6479103 complement(1388178..1388333) 1 NC_011072.1 IS1239 transposase 1388333 6479103 SPG_1438 Streptococcus pneumoniae G54 IS1239 transposase YP_002038145.1 1388178 R 512566 CDS YP_002038146.1 194398362 6479693 complement(1388355..1389188) 1 NC_011072.1 IS1239 transposase 1389188 6479693 SPG_1439 Streptococcus pneumoniae G54 IS1239 transposase YP_002038146.1 1388355 R 512566 CDS YP_002038147.1 194397777 6480110 complement(1389562..1389960) 1 NC_011072.1 identified by match to protein family HMM PF00583; GNAT family acetyltransferase 1389960 6480110 SPG_1440 Streptococcus pneumoniae G54 GNAT family acetyltransferase YP_002038147.1 1389562 R 512566 CDS YP_002038148.1 194397327 6480434 complement(1390333..1390815) 1 NC_011072.1 necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus; transcription elongation factor GreA 1390815 greA 6480434 greA Streptococcus pneumoniae G54 transcription elongation factor GreA YP_002038148.1 1390333 R 512566 CDS YP_002038149.1 194396990 6479923 complement(1390886..1392541) 1 NC_011072.1 identified by match to protein family HMM PF02618; match to protein family HMM TIGR00247; hypothetical protein 1392541 6479923 SPG_1442 Streptococcus pneumoniae G54 hypothetical protein YP_002038149.1 1390886 R 512566 CDS YP_002038150.1 194398171 6480107 complement(1392622..1393116) 1 NC_011072.1 identified by match to protein family HMM PF00583; GNAT family acetyltransferase 1393116 6480107 SPG_1443 Streptococcus pneumoniae G54 GNAT family acetyltransferase YP_002038150.1 1392622 R 512566 CDS YP_002038151.1 194397699 6480208 complement(1393113..1393577) 1 NC_011072.1 identified by match to protein family HMM PF00583; GNAT family acetyltransferase 1393577 6480208 SPG_1444 Streptococcus pneumoniae G54 GNAT family acetyltransferase YP_002038151.1 1393113 R 512566 CDS YP_002038152.1 194398270 6479129 complement(1393587..1394921) 1 NC_011072.1 Catalyzes the formation of UDP-N-acetylmuramoyl-L-alanine from UDP-N-acetylmuramate and L-alanine in peptidoglycan synthesis; UDP-N-acetylmuramate--L-alanine ligase 1394921 murC 6479129 murC Streptococcus pneumoniae G54 UDP-N-acetylmuramate--L-alanine ligase YP_002038152.1 1393587 R 512566 CDS YP_002038153.1 194397790 6478679 complement(1394932..1395549) 1 NC_011072.1 identified by glimmer; putative; hypothetical protein 1395549 6478679 SPG_1446 Streptococcus pneumoniae G54 hypothetical protein YP_002038153.1 1394932 R 512566 CDS YP_002038154.1 194397845 6479945 complement(1395597..1398695) 1 NC_011072.1 identified by match to protein family HMM PF00176; match to protein family HMM PF00271; match to protein family HMM PF04434; match to protein family HMM PF08455; SNF2 family protein 1398695 6479945 SPG_1447 Streptococcus pneumoniae G54 SNF2 family protein YP_002038154.1 1395597 R 512566 CDS YP_002038155.1 194396900 6480297 complement(1398788..1399954) 1 NC_011072.1 identified by match to protein family HMM PF00155; aminotransferase 1399954 6480297 SPG_1449 Streptococcus pneumoniae G54 aminotransferase YP_002038155.1 1398788 R 512566 CDS YP_002038156.1 194398561 6479351 complement(1399962..1401056) 1 NC_011072.1 catalyzes the formation of cystathionine from L-cysteine and O-succinyl-L-homoserine; cystathionine gamma-synthase 1401056 metB 6479351 metB Streptococcus pneumoniae G54 cystathionine gamma-synthase YP_002038156.1 1399962 R 512566 CDS YP_002038157.1 194397461 6479090 complement(1401213..1401758) 1 NC_011072.1 contains potential frameshift; identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 1401758 6479090 SPG_1451 Streptococcus pneumoniae G54 ABC transporter ATP-binding protein YP_002038157.1 1401213 R 512566 CDS YP_002038158.1 194396986 6480268 complement(1401794..1402333) 1 NC_011072.1 contains potential frameshift; identified by glimmer; putative; hypothetical protein 1402333 6480268 SPG_1452 Streptococcus pneumoniae G54 hypothetical protein YP_002038158.1 1401794 R 512566 CDS YP_002038159.1 194398651 6479631 complement(1402342..1402635) 1 NC_011072.1 contains potential frameshift; identified by glimmer; putative; hypothetical protein 1402635 6479631 SPG_1453 Streptococcus pneumoniae G54 hypothetical protein YP_002038159.1 1402342 R 512566 CDS YP_002038160.1 194398317 6479358 complement(1403048..1405006) 1 NC_011072.1 identified by match to protein family HMM PF00496; oligopeptide ABC transporter oligopeptide-binding protein 1405006 6479358 SPG_1454 Streptococcus pneumoniae G54 oligopeptide ABC transporter oligopeptide-binding protein YP_002038160.1 1403048 R 512566 CDS YP_002038161.1 194397228 6479040 complement(1405209..1406831) 1 NC_011072.1 identified by match to protein family HMM PF01943; polysaccharide biosynthesis protein 1406831 6479040 SPG_1455 Streptococcus pneumoniae G54 polysaccharide biosynthesis protein YP_002038161.1 1405209 R 512566 CDS YP_002038162.1 194396806 6480031 1406937..1408382 1 NC_011072.1 involved in cell wall formation; peptidoglycan synthesis; cytoplasmic enzyme; catalyzes the addition of lysine to UDP-N-acetylmuramoyl-L-alanyl-D-glutamate forming UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysine; UDP-N-acetylmuramoylalanyl-D-glutamate--L-lysine ligase 1408382 murE 6480031 murE Streptococcus pneumoniae G54 UDP-N-acetylmuramoylalanyl-D-glutamate--L-lysine ligase YP_002038162.1 1406937 D 512566 CDS YP_002038163.1 194398515 6479435 complement(1408428..1408622) 1 NC_011072.1 identified by match to protein family HMM PF05532; hypothetical protein 1408622 6479435 SPG_1457 Streptococcus pneumoniae G54 hypothetical protein YP_002038163.1 1408428 R 512566 CDS YP_002038164.1 194398044 6480387 complement(1408728..1409318) 1 NC_011072.1 identified by match to protein family HMM PF08820; hypothetical protein 1409318 6480387 SPG_1458 Streptococcus pneumoniae G54 hypothetical protein YP_002038164.1 1408728 R 512566 CDS YP_002038165.1 194396741 6478672 complement(1409355..1409867) 1 NC_011072.1 hypothetical protein 1409867 6478672 SPG_1459 Streptococcus pneumoniae G54 hypothetical protein YP_002038165.1 1409355 R 512566 CDS YP_002038166.1 194397199 6479877 complement(1409954..1410889) 1 NC_011072.1 catalyzes the hydrolysis of pyrophosphate to phosphate; putative manganese-dependent inorganic pyrophosphatase 1410889 ppa 6479877 ppa Streptococcus pneumoniae G54 putative manganese-dependent inorganic pyrophosphatase YP_002038166.1 1409954 R 512566 CDS YP_002038167.1 194398240 6480397 complement(1410917..1411258) 1 NC_011072.1 identified by match to protein family HMM PF01541; hypothetical protein 1411258 6480397 SPG_1461 Streptococcus pneumoniae G54 hypothetical protein YP_002038167.1 1410917 R 512566 CDS YP_002038168.1 194398665 6479204 complement(1411248..1411997) 1 NC_011072.1 identified by match to protein family HMM PF05175; hypothetical protein 1411997 6479204 SPG_1462 Streptococcus pneumoniae G54 hypothetical protein YP_002038168.1 1411248 R 512566 CDS YP_002038169.1 194397892 6478754 complement(1412051..1412410) 1 NC_011072.1 identified by glimmer; putative; hypothetical protein 1412410 6478754 SPG_1463 Streptococcus pneumoniae G54 hypothetical protein YP_002038169.1 1412051 R 512566 CDS YP_002038170.1 194396987 6478908 complement(1412412..1413812) 1 NC_011072.1 identified by match to protein family HMM PF00160; match to protein family HMM PF00702; match to protein family HMM PF05116; match to protein family HMM PF08282; match to protein family HMM TIGR00099; match to protein family HMM TIGR01484; Cof family protein/peptidyl-prolyl cis-trans isomerase 1413812 6478908 SPG_1464 Streptococcus pneumoniae G54 Cof family protein/peptidyl-prolyl cis-trans isomerase YP_002038170.1 1412412 R 512566 CDS YP_002038171.1 194396735 6479713 complement(1414107..1414346) 1 NC_011072.1 binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit; 30S ribosomal protein S18 1414346 rpsR 6479713 rpsR Streptococcus pneumoniae G54 30S ribosomal protein S18 YP_002038171.1 1414107 R 512566 CDS YP_002038172.1 194397185 6479808 complement(1414378..1414848) 1 NC_011072.1 binds to single stranded DNA and may facilitate the binding and interaction of other proteins to DNA; single-stranded DNA-binding protein 1414848 6479808 SPG_1466 Streptococcus pneumoniae G54 single-stranded DNA-binding protein YP_002038172.1 1414378 R 512566 CDS YP_002038173.1 194398723 6479516 complement(1414860..1415150) 1 NC_011072.1 binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21; 30S ribosomal protein S6 1415150 rpsF 6479516 rpsF Streptococcus pneumoniae G54 30S ribosomal protein S6 YP_002038173.1 1414860 R 512566 CDS YP_002038174.1 194397060 6479094 complement(1415303..1416646) 1 NC_011072.1 catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; asparaginyl-tRNA synthetase 1416646 asnC 6479094 asnC Streptococcus pneumoniae G54 asparaginyl-tRNA synthetase YP_002038174.1 1415303 R 512566 CDS YP_002038175.1 194397211 6479740 complement(1416665..1417030) 1 NC_011072.1 identified by match to protein family HMM PF00903; glyoxalase family protein 1417030 6479740 SPG_1469 Streptococcus pneumoniae G54 glyoxalase family protein YP_002038175.1 1416665 R 512566 CDS YP_002038176.1 194396750 6480670 complement(1417023..1418210) 1 NC_011072.1 catalyzes the formation of oxalozcetate and L-glutamate from L-aspartate and 2-oxoglutarate; aspartate aminotransferase 1418210 aspC 6480670 aspC Streptococcus pneumoniae G54 aspartate aminotransferase YP_002038176.1 1417023 R 512566 CDS YP_002038177.1 194397631 6479843 complement(1418207..1418695) 1 NC_011072.1 hypothetical protein 1418695 6479843 SPG_1471 Streptococcus pneumoniae G54 hypothetical protein YP_002038177.1 1418207 R 512566 CDS YP_002038178.1 194396663 6478862 complement(1418762..1418878) 1 NC_011072.1 identified by glimmer; putative; hypothetical protein 1418878 6478862 SPG_1472 Streptococcus pneumoniae G54 hypothetical protein YP_002038178.1 1418762 R 512566 CDS YP_002038179.1 194398576 6479744 1419016..1419564 1 NC_011072.1 identified by match to protein family HMM PF02525; match to protein family HMM PF03358; NADPH-dependent FMN reductase 1419564 6479744 SPG_1473 Streptococcus pneumoniae G54 NADPH-dependent FMN reductase YP_002038179.1 1419016 D 512566 CDS YP_002038180.1 194398175 6478985 complement(1419842..1420570) 1 NC_011072.1 identified by match to protein family HMM PF03883; hypothetical protein 1420570 6478985 SPG_1474 Streptococcus pneumoniae G54 hypothetical protein YP_002038180.1 1419842 R 512566 CDS YP_002038181.1 194397541 6480032 complement(1420649..1420813) 1 NC_011072.1 hypothetical protein 1420813 6480032 SPG_1475 Streptococcus pneumoniae G54 hypothetical protein YP_002038181.1 1420649 R 512566 CDS YP_002038182.1 194396930 6479128 complement(1420980..1422575) 1 NC_011072.1 hypothetical protein 1422575 6479128 SPG_1476 Streptococcus pneumoniae G54 hypothetical protein YP_002038182.1 1420980 R 512566 CDS YP_002038183.1 194396850 6479835 complement(1422587..1422997) 1 NC_011072.1 cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+); peptide deformylase 1422997 defA 6479835 defA Streptococcus pneumoniae G54 peptide deformylase YP_002038183.1 1422587 R 512566 CDS YP_002038184.1 194398508 6479458 complement(1423113..1423904) 1 NC_011072.1 YghU; B2989; one of eight putative glutathione transferase proteins from E. coli; putative glutathione S-transferase YghU 1423904 6479458 SPG_1478 Streptococcus pneumoniae G54 putative glutathione S-transferase YghU YP_002038184.1 1423113 R 512566 CDS YP_002038185.1 194398720 6480590 complement(1423917..1426613) 1 NC_011072.1 identified by match to protein family HMM PF00122; match to protein family HMM PF00689; match to protein family HMM PF00690; match to protein family HMM PF00702; match to protein family HMM TIGR01494; E1-E2 family cation-transporting ATPase 1426613 6480590 SPG_1479 Streptococcus pneumoniae G54 E1-E2 family cation-transporting ATPase YP_002038185.1 1423917 R 512566 CDS YP_002038186.1 194397077 6479333 1426917..1428101 1 NC_011072.1 identified by match to protein family HMM PF01545; match to protein family HMM TIGR01297; cation efflux family protein 1428101 6479333 SPG_1480 Streptococcus pneumoniae G54 cation efflux family protein YP_002038186.1 1426917 D 512566 CDS YP_002038187.1 194396756 6480214 complement(1428244..1430115) 1 NC_011072.1 identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 1430115 6480214 SPG_1481 Streptococcus pneumoniae G54 ABC transporter ATP-binding protein YP_002038187.1 1428244 R 512566 CDS YP_002038188.1 194397214 6479898 complement(1430112..1431311) 1 NC_011072.1 catalyzes the addition and repair of the 3'-terminal CCA sequence in tRNA; these proteins belong to the CCA-adding enzyme subfamily 2 which does not have phosphohydrolase activity; tRNA CCA-pyrophosphorylase 1431311 6479898 SPG_1482 Streptococcus pneumoniae G54 tRNA CCA-pyrophosphorylase YP_002038188.1 1430112 R 512566 CDS YP_002038189.1 194396706 6480280 complement(1431308..1432075) 1 NC_011072.1 catalyzes the reduction of 2,3-dihydrodipicolinate to 2,3,4,5-tetrahydrodipicolinate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate reductase 1432075 dapB 6480280 dapB Streptococcus pneumoniae G54 dihydrodipicolinate reductase YP_002038189.1 1431308 R 512566 CDS YP_002038190.1 194397275 6480626 complement(1432352..1433200) 1 NC_011072.1 identified by glimmer; putative; hypothetical protein 1433200 6480626 SPG_1484 Streptococcus pneumoniae G54 hypothetical protein YP_002038190.1 1432352 R 512566 CDS YP_002038191.1 194397900 6479549 complement(1433202..1433576) 1 NC_011072.1 identified by match to protein family HMM PF06619; hypothetical protein 1433576 6479549 SPG_1485 Streptococcus pneumoniae G54 hypothetical protein YP_002038191.1 1433202 R 512566 CDS YP_002038192.1 194398484 6479117 complement(1433650..1435002) 1 NC_011072.1 catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; phosphoglucosamine mutase 1435002 glmM 6479117 glmM Streptococcus pneumoniae G54 phosphoglucosamine mutase YP_002038192.1 1433650 R 512566 CDS YP_002038193.1 194396917 6480606 complement(1435026..1435805) 1 NC_011072.1 identified by match to protein family HMM PF07949; hypothetical protein 1435805 6480606 SPG_1487 Streptococcus pneumoniae G54 hypothetical protein YP_002038193.1 1435026 R 512566 CDS YP_002038194.1 194397645 6480600 complement(1435792..1436649) 1 NC_011072.1 identified by match to protein family HMM PF02457; match to protein family HMM TIGR00159; hypothetical protein 1436649 6480600 SPG_1488 Streptococcus pneumoniae G54 hypothetical protein YP_002038194.1 1435792 R 512566 CDS YP_002038195.1 194398040 6479230 1436785..1437753 1 NC_011072.1 identified by match to protein family HMM PF00070; match to protein family HMM PF07992; pyridine nucleotide-disulphide oxidoreductase family protein 1437753 6479230 SPG_1489 Streptococcus pneumoniae G54 pyridine nucleotide-disulphide oxidoreductase family protein YP_002038195.1 1436785 D 512566 CDS YP_002038196.1 194398522 6479505 complement(1437787..1438698) 1 NC_011072.1 identified by match to protein family HMM PF02650; match to protein family HMM TIGR00647; hypothetical protein 1438698 6479505 SPG_1490 Streptococcus pneumoniae G54 hypothetical protein YP_002038196.1 1437787 R 512566 CDS YP_002038197.1 194398085 6480654 complement(1438695..1439672) 1 NC_011072.1 identified by match to protein family HMM PF01933; match to protein family HMM TIGR01826; hypothetical protein 1439672 6480654 SPG_1491 Streptococcus pneumoniae G54 hypothetical protein YP_002038197.1 1438695 R 512566 CDS YP_002038198.1 194398724 6478758 complement(1439669..1440559) 1 NC_011072.1 identified by glimmer; putative; hypothetical protein 1440559 6478758 SPG_1492 Streptococcus pneumoniae G54 hypothetical protein YP_002038198.1 1439669 R 512566 CDS YP_002038199.1 194397045 6479381 complement(1440611..1440991) 1 NC_011072.1 identified by match to protein family HMM PF01042; match to protein family HMM TIGR00004; endoribonuclease L-PSP 1440991 6479381 SPG_1493 Streptococcus pneumoniae G54 endoribonuclease L-PSP YP_002038199.1 1440611 R 512566 CDS YP_002038200.1 194397246 6480523 complement(1441002..1441589) 1 NC_011072.1 binds guanine nucleotides; in Escherichia coli depletion results in defective cell division and filamentation; in Bacillus subtilis this gene is essential; ribosome biogenesis GTP-binding protein YsxC 1441589 engB 6480523 engB Streptococcus pneumoniae G54 ribosome biogenesis GTP-binding protein YsxC YP_002038200.1 1441002 R 512566 CDS YP_002038201.1 194397730 6480682 complement(1441598..1442830) 1 NC_011072.1 binds and unfolds substrates as part of the ClpXP protease; ATP-dependent protease ATP-binding subunit ClpX 1442830 clpX 6480682 clpX Streptococcus pneumoniae G54 ATP-dependent protease ATP-binding subunit ClpX YP_002038201.1 1441598 R 512566 CDS YP_002038202.1 194398463 6480417 complement(1442862..1443032) 1 NC_011072.1 hypothetical protein 1443032 6480417 SPG_1496 Streptococcus pneumoniae G54 hypothetical protein YP_002038202.1 1442862 R 512566 CDS YP_002038203.1 194396823 6479932 complement(1443032..1443538) 1 NC_011072.1 identified by match to protein family HMM PF00186; dihydrofolate reductase 1443538 folA 6479932 folA Streptococcus pneumoniae G54 dihydrofolate reductase YP_002038203.1 1443032 R 512566 CDS YP_002038204.1 194398107 6479462 complement(1443668..1444186) 1 NC_011072.1 identified by match to protein family HMM PF00210; ferritin-like domain 1444186 6479462 SPG_1498 Streptococcus pneumoniae G54 ferritin-like domain YP_002038204.1 1443668 R 512566 CDS YP_002038205.1 194397706 6480618 complement(1444682..1446154) 1 NC_011072.1 identified by match to protein family HMM PF01183; match to protein family HMM PF01473; endo-beta-N-acetylglucosaminidase 1446154 lytC 6480618 lytC Streptococcus pneumoniae G54 endo-beta-N-acetylglucosaminidase YP_002038205.1 1444682 R 512566 CDS YP_002038206.1 194398071 6480356 complement(1446225..1446983) 1 NC_011072.1 Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate; triosephosphate isomerase 1446983 tpiA 6480356 tpiA Streptococcus pneumoniae G54 triosephosphate isomerase YP_002038206.1 1446225 R 512566 CDS YP_002038207.1 194398529 6479436 complement(1447081..1447758) 1 NC_011072.1 identified by match to protein family HMM PF04271; match to protein family HMM TIGR01446; hypothetical protein 1447758 6479436 SPG_1501 Streptococcus pneumoniae G54 hypothetical protein YP_002038207.1 1447081 R 512566 CDS YP_002038208.1 194398064 6480006 complement(1447767..1448711) 1 NC_011072.1 catalyzes the formation of O-succinyl-L-homoserine from succinyl-CoA and L-homoserine in methionine biosynthesis; homoserine O-succinyltransferase 1448711 metA 6480006 metA Streptococcus pneumoniae G54 homoserine O-succinyltransferase YP_002038208.1 1447767 R 512566 CDS YP_002038209.1 194398584 6479618 complement(1448893..1449405) 1 NC_011072.1 catalyzes a salvage reaction resulting in the formation of AMP which is metabolically less costly than a de novo synthesis; adenine phosphoribosyltransferase 1449405 6479618 SPG_1503 Streptococcus pneumoniae G54 adenine phosphoribosyltransferase YP_002038209.1 1448893 R 512566 CDS YP_002038210.1 194397414 6479321 complement(1449492..1450250) 1 NC_011072.1 identified by match to protein family HMM PF08241; match to protein family HMM PF08242; hypothetical protein 1450250 6479321 SPG_1504 Streptococcus pneumoniae G54 hypothetical protein YP_002038210.1 1449492 R 512566 CDS YP_002038211.1 194397838 6480560 complement(1450751..1451881) 1 NC_011072.1 identified by match to protein family HMM PF00005; match to protein family HMM PF03459; match to protein family HMM PF08402; ABC transporter ATP-binding protein 1451881 6480560 SPG_1505 Streptococcus pneumoniae G54 ABC transporter ATP-binding protein YP_002038211.1 1450751 R 512566 CDS YP_002038212.1 194398310 6480456 1451982..1452104 1 NC_011072.1 hypothetical protein 1452104 6480456 SPG_1506 Streptococcus pneumoniae G54 hypothetical protein YP_002038212.1 1451982 D 512566 CDS YP_002038213.1 194397177 6480329 complement(1452331..1452906) 1 NC_011072.1 identified by match to protein family HMM PF00857; isochorismatase family protein 1452906 6480329 SPG_1508 Streptococcus pneumoniae G54 isochorismatase family protein YP_002038213.1 1452331 R 512566 CDS YP_002038214.1 194397588 6478994 complement(1452906..1453694) 1 NC_011072.1 CodY; DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase (By similarity). It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor; transcriptional repressor CodY 1453694 codY 6478994 codY Streptococcus pneumoniae G54 transcriptional repressor CodY YP_002038214.1 1452906 R 512566 CDS YP_002038215.1 194396853 6478953 complement(1453958..1455532) 1 NC_011072.1 identified by match to protein family HMM PF00270; match to protein family HMM PF00271; ATP-dependent RNA helicase 1455532 6478953 SPG_1510 Streptococcus pneumoniae G54 ATP-dependent RNA helicase YP_002038215.1 1453958 R 512566 CDS YP_002038216.1 194397331 6478867 complement(1455731..1456957) 1 NC_011072.1 identified by match to protein family HMM PF07690; oxalate:formate antiporter 1456957 6478867 SPG_1511 Streptococcus pneumoniae G54 oxalate:formate antiporter YP_002038216.1 1455731 R 512566 CDS YP_002038217.1 194396892 6480751 1457150..1458466 1 NC_011072.1 Involved in disulfide oxidoreductase activity and electron transport; pyridine nucleotide-disulfide oxidoreductase 1458466 6480751 SPG_1512 Streptococcus pneumoniae G54 pyridine nucleotide-disulfide oxidoreductase YP_002038217.1 1457150 D 512566 CDS YP_002038218.1 194398556 6478969 1458565..1459908 1 NC_011072.1 identified by match to protein family HMM PF08245; match to protein family HMM PF08353; hypothetical protein 1459908 6478969 SPG_1513 Streptococcus pneumoniae G54 hypothetical protein YP_002038218.1 1458565 D 512566 CDS YP_002038219.1 194398110 6479540 1459908..1460690 1 NC_011072.1 identified by match to protein family HMM PF07685; hypothetical protein 1460690 6479540 SPG_1514 Streptococcus pneumoniae G54 hypothetical protein YP_002038219.1 1459908 D 512566 CDS YP_002038220.1 194397676 6479067 1460816..1461898 1 NC_011072.1 identified by match to protein family HMM PF00557; match to protein family HMM PF01321; proline dipeptidase PepQ 1461898 pepQ 6479067 pepQ Streptococcus pneumoniae G54 proline dipeptidase PepQ YP_002038220.1 1460816 D 512566 CDS YP_002038221.1 194397152 6479073 complement(1462219..1463052) 1 NC_011072.1 identified by match to protein family HMM PF00665; IS3-Spn1 transposase 1463052 6479073 SPG_1516 Streptococcus pneumoniae G54 IS3-Spn1 transposase YP_002038221.1 1462219 R 512566 CDS YP_002038222.1 194396732 6479995 complement(1463052..1463219) 1 NC_011072.1 contains potential frameshift; transposase IS3-Spn1 1463219 6479995 SPG_1517 Streptococcus pneumoniae G54 transposase IS3-Spn1 YP_002038222.1 1463052 R 512566 CDS YP_002038223.1 194398403 6479750 complement(1463356..1463568) 1 NC_011072.1 contains potential frameshift; IS3-Spn1 transposase 1463568 6479750 SPG_1518 Streptococcus pneumoniae G54 IS3-Spn1 transposase YP_002038223.1 1463356 R 512566 CDS YP_002038224.1 194396650 6479722 1463644..1463763 1 NC_011072.1 identified by glimmer; putative; hypothetical protein 1463763 6479722 SPG_1519 Streptococcus pneumoniae G54 hypothetical protein YP_002038224.1 1463644 D 512566 CDS YP_002038225.1 194398093 6479640 complement(1463792..1464253) 1 NC_011072.1 hypothetical protein 1464253 6479640 SPG_1520 Streptococcus pneumoniae G54 hypothetical protein YP_002038225.1 1463792 R 512566 CDS YP_002038226.1 194396722 6479660 complement(1464231..1465004) 1 NC_011072.1 catalyzes the formation of 4-amino-2-methyl-5-diphosphomethylpyrimidine; phosphomethylpyrimidine kinase 1465004 6479660 SPG_1521 Streptococcus pneumoniae G54 phosphomethylpyrimidine kinase YP_002038226.1 1464231 R 512566 CDS YP_002038227.1 194397044 6480225 complement(1464994..1465743) 1 NC_011072.1 mediates pseudouridylation (positions 38, 39, 40) at the tRNA anticodon region which contributes to the structural stability; tRNA pseudouridine synthase A 1465743 truA 6480225 truA Streptococcus pneumoniae G54 tRNA pseudouridine synthase A YP_002038227.1 1464994 R 512566 CDS YP_002038228.1 194396696 6479984 1465923..1466084 1 NC_011072.1 hypothetical protein 1466084 6479984 SPG_1524 Streptococcus pneumoniae G54 hypothetical protein YP_002038228.1 1465923 D 512566 CDS YP_002038229.1 194397448 6479700 complement(1466056..1467207) 1 NC_011072.1 identified by match to protein family HMM PF07690; major facilitator family transporter 1467207 6479700 SPG_1523 Streptococcus pneumoniae G54 major facilitator family transporter YP_002038229.1 1466056 R 512566 CDS YP_002038230.1 194398615 6480179 complement(1467447..1468076) 1 NC_011072.1 hypothetical protein 1468076 6480179 SPG_1525 Streptococcus pneumoniae G54 hypothetical protein YP_002038230.1 1467447 R 512566 CDS YP_002038231.1 194398034 6478903 complement(1468079..1468417) 1 NC_011072.1 identified by match to protein family HMM PF03831; match to protein family HMM PF08274; match to protein family HMM TIGR00686; alkylphosphonate utilization operon protein PhnA 1468417 6478903 SPG_1526 Streptococcus pneumoniae G54 alkylphosphonate utilization operon protein PhnA YP_002038231.1 1468079 R 512566 CDS YP_002038232.1 194398163 6478928 complement(1468547..1469218) 1 NC_011072.1 Catalyzes the formation of (d)CDP from ATP and (d)CMP; cytidylate kinase 1469218 cmk 6478928 cmk Streptococcus pneumoniae G54 cytidylate kinase YP_002038232.1 1468547 R 512566 CDS YP_002038233.1 194397583 6480760 complement(1469227..1469703) 1 NC_011072.1 hypothetical protein 1469703 6480760 SPG_1528 Streptococcus pneumoniae G54 hypothetical protein YP_002038233.1 1469227 R 512566 CDS YP_002038234.1 194398290 6478988 1469755..1469961 1 NC_011072.1 ferredoxin 1469961 6478988 SPG_1529 Streptococcus pneumoniae G54 ferredoxin YP_002038234.1 1469755 D 512566 CDS YP_002038235.1 194397913 6479158 complement(1470012..1470977) 1 NC_011072.1 identified by match to protein family HMM PF00535; group 2 family glycosyl transferase 1470977 6479158 SPG_1530 Streptococcus pneumoniae G54 group 2 family glycosyl transferase YP_002038235.1 1470012 R 512566 CDS YP_002038236.1 194398413 6479373 complement(1470979..1471998) 1 NC_011072.1 identified by match to protein family HMM PF00106; match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF04321; match to protein family HMM PF07993; match to protein family HMM TIGR01179; UDP-glucose 4-epimerase 1471998 6479373 SPG_1531 Streptococcus pneumoniae G54 UDP-glucose 4-epimerase YP_002038236.1 1470979 R 512566 CDS YP_002038237.1 194397668 6480808 complement(1472344..1473447) 1 NC_011072.1 identified by match to protein family HMM PF01266; FAD dependent oxidoreductase 1473447 6480808 SPG_1532 Streptococcus pneumoniae G54 FAD dependent oxidoreductase YP_002038237.1 1472344 R 512566 CDS YP_002038238.1 194396766 6479376 complement(1473464..1474261) 1 NC_011072.1 identified by match to protein family HMM PF01784; match to protein family HMM TIGR00486; hypothetical protein 1474261 6479376 SPG_1533 Streptococcus pneumoniae G54 hypothetical protein YP_002038238.1 1473464 R 512566 CDS YP_002038239.1 194398610 6479839 complement(1474248..1474925) 1 NC_011072.1 identified by glimmer; putative; hypothetical protein 1474925 6479839 SPG_1534 Streptococcus pneumoniae G54 hypothetical protein YP_002038239.1 1474248 R 512566 CDS YP_002038240.1 194398153 6478910 complement(1475027..1477363) 1 NC_011072.1 identified by match to protein family HMM PF00122; match to protein family HMM PF00702; match to protein family HMM TIGR01494; E1-E2 family cation-transporting ATPase 1477363 6478910 SPG_1535 Streptococcus pneumoniae G54 E1-E2 family cation-transporting ATPase YP_002038240.1 1475027 R 512566 CDS YP_002038241.1 194397966 6480333 1477496..1478245 1 NC_011072.1 identified by match to protein family HMM PF01553; acyltransferase domain-containing protein 1478245 6480333 SPG_1536 Streptococcus pneumoniae G54 acyltransferase domain-containing protein YP_002038241.1 1477496 D 512566 CDS YP_002038242.1 194396956 6479587 complement(1478538..1479152) 1 NC_011072.1 identified by match to protein family HMM PF03596; match to protein family HMM TIGR00779; cadmium resistance transporter 1479152 6479587 SPG_1537 Streptococcus pneumoniae G54 cadmium resistance transporter YP_002038242.1 1478538 R 512566 CDS YP_002038243.1 194398205 6479834 complement(1479965..1480234) 1 NC_011072.1 primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence; 30S ribosomal protein S15 1480234 rpsO 6479834 rpsO Streptococcus pneumoniae G54 30S ribosomal protein S15 YP_002038243.1 1479965 R 512566 CDS YP_002038244.1 194398733 6479424 complement(1480513..1481004) 1 NC_011072.1 hypothetical protein 1481004 6479424 SPG_1539 Streptococcus pneumoniae G54 hypothetical protein YP_002038244.1 1480513 R 512566 CDS YP_002038245.1 194397773 6478954 1481067..1481189 1 NC_011072.1 identified by glimmer; putative; hypothetical protein 1481189 6478954 SPG_1540 Streptococcus pneumoniae G54 hypothetical protein YP_002038245.1 1481067 D 512566 CDS YP_002038246.1 194397303 6480526 1481863..1482084 1 NC_011072.1 hypothetical protein 1482084 6480526 SPG_1541 Streptococcus pneumoniae G54 hypothetical protein YP_002038246.1 1481863 D 512566 CDS YP_002038247.1 194397191 6479179 1482244..1484187 1 NC_011072.1 catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr); threonyl-tRNA synthetase 1484187 thrS 6479179 thrS Streptococcus pneumoniae G54 threonyl-tRNA synthetase YP_002038247.1 1482244 D 512566 CDS YP_002038248.1 194396845 6478746 complement(1484236..1485210) 1 NC_011072.1 identified by match to protein family HMM PF02518; histidine kinase 1485210 6478746 SPG_1543 Streptococcus pneumoniae G54 histidine kinase YP_002038248.1 1484236 R 512566 CDS YP_002038249.1 194398437 6479223 complement(1485203..1485880) 1 NC_011072.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00486; response regulator 1485880 6479223 SPG_1544 Streptococcus pneumoniae G54 response regulator YP_002038249.1 1485203 R 512566 CDS YP_002038250.1 194397571 6480588 1486036..1487109 1 NC_011072.1 hypothetical protein 1487109 6480588 SPG_1545 Streptococcus pneumoniae G54 hypothetical protein YP_002038250.1 1486036 D 512566 CDS YP_002038251.1 194397573 6478827 complement(1487200..1487502) 1 NC_011072.1 hypothetical protein 1487502 6478827 SPG_1546 Streptococcus pneumoniae G54 hypothetical protein YP_002038251.1 1487200 R 512566 CDS YP_002038252.1 194396960 6479269 complement(1487570..1488007) 1 NC_011072.1 identified by match to protein family HMM PF02082; RRF2 family protein 1488007 6479269 SPG_1547 Streptococcus pneumoniae G54 RRF2 family protein YP_002038252.1 1487570 R 512566 CDS YP_002038253.1 194398686 6479827 complement(1488083..1488925) 1 NC_011072.1 identified by match to protein family HMM PF00149; hypothetical protein 1488925 6479827 SPG_1548 Streptococcus pneumoniae G54 hypothetical protein YP_002038253.1 1488083 R 512566 CDS YP_002038254.1 194397132 6478878 1489037..1489687 1 NC_011072.1 identified by match to protein family HMM PF01047; match to protein family HMM PF01325; match to protein family HMM PF02742; match to protein family HMM PF04023; iron-dependent transcriptional regulator 1489687 dtxR 6478878 dtxR Streptococcus pneumoniae G54 iron-dependent transcriptional regulator YP_002038254.1 1489037 D 512566 CDS YP_002038255.1 194397805 6479804 1489668..1489838 1 NC_011072.1 hypothetical protein 1489838 6479804 SPG_1550 Streptococcus pneumoniae G54 hypothetical protein YP_002038255.1 1489668 D 512566 CDS YP_002038256.1 194397439 6480244 1489864..1490541 1 NC_011072.1 identified by glimmer; putative; hypothetical protein 1490541 6480244 SPG_1551 Streptococcus pneumoniae G54 hypothetical protein YP_002038256.1 1489864 D 512566 CDS YP_002038257.1 194398535 6480308 1490643..1491056 1 NC_011072.1 hypothetical protein 1491056 6480308 SPG_1552 Streptococcus pneumoniae G54 hypothetical protein YP_002038257.1 1490643 D 512566 CDS YP_002038258.1 194398086 6480001 1491330..1491491 1 NC_011072.1 hypothetical protein 1491491 6480001 SPG_1553 Streptococcus pneumoniae G54 hypothetical protein YP_002038258.1 1491330 D 512566 CDS YP_002038259.1 194398083 6478947 complement(1491530..1491973) 1 NC_011072.1 hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr); possible defense mechanism against a harmful effect of D-tyrosine; D-tyrosyl-tRNA(Tyr) deacylase 1491973 6478947 SPG_1554 Streptococcus pneumoniae G54 D-tyrosyl-tRNA(Tyr) deacylase YP_002038259.1 1491530 R 512566 CDS YP_002038260.1 194397589 6478756 complement(1492003..1494225) 1 NC_011072.1 identified by match to protein family HMM PF01966; match to protein family HMM PF02824; match to protein family HMM PF04607; match to protein family HMM TIGR00691; GTP pyrophosphokinase 1494225 6478756 SPG_1555 Streptococcus pneumoniae G54 GTP pyrophosphokinase YP_002038260.1 1492003 R 512566 CDS YP_002038261.1 194397119 6479153 1495219..1495848 1 NC_011072.1 identified by match to protein family HMM PF00753; hypothetical protein 1495848 6479153 SPG_1556 Streptococcus pneumoniae G54 hypothetical protein YP_002038261.1 1495219 D 512566 CDS YP_002038262.1 194398395 6480422 complement(1495971..1497863) 1 NC_011072.1 identified by match to protein family HMM PF01431; match to protein family HMM PF05649; endopeptidase O 1497863 6480422 SPG_1557 Streptococcus pneumoniae G54 endopeptidase O YP_002038262.1 1495971 R 512566 CDS YP_002038263.1 194396962 6478858 1498090..1498812 1 NC_011072.1 Dintilhac A, Mol Microbiol. 1997 Aug;25(4):727-39.; identified by match to protein family HMM PF00005; manganese ABC transporter ATP-binding protein 1498812 psaB 6478858 psaB Streptococcus pneumoniae G54 manganese ABC transporter ATP-binding protein YP_002038263.1 1498090 D 512566 CDS YP_002038264.1 194398501 6480715 1498809..1499657 1 NC_011072.1 Dintilhac A, Mol Microbiol. 1997 Aug;25(4):727-39.; identified by match to protein family HMM PF00950; manganese ABC transporter permease 1499657 psaC 6480715 psaC Streptococcus pneumoniae G54 manganese ABC transporter permease YP_002038264.1 1498809 D 512566 CDS YP_002038265.1 194398710 6480660 1499689..1500618 1 NC_011072.1 Dintilhac A, Mol Microbiol. 1997 Aug;25(4):727-39.; identified by match to protein family HMM PF01297; manganese ABC transporter substrate-binding lipoprotein 1500618 psaA 6480660 psaA Streptococcus pneumoniae G54 manganese ABC transporter substrate-binding lipoprotein YP_002038265.1 1499689 D 512566 CDS YP_002038266.1 194396914 6479483 1500741..1501232 1 NC_011072.1 antioxidant activity; thioredoxin-dependent thiol peroxidase; forms homodimers in solution; shows substrate specificity to alkyl hydroperoxides; periplasmic protein; thiol peroxidase 1501232 tpx 6479483 tpx Streptococcus pneumoniae G54 thiol peroxidase YP_002038266.1 1500741 D 512566 CDS YP_002038267.1 194397244 6480415 complement(1501328..1504036) 1 NC_011072.1 identified by match to protein family HMM PF02687; ABC transporter permease 1504036 6480415 SPG_1562 Streptococcus pneumoniae G54 ABC transporter permease YP_002038267.1 1501328 R 512566 CDS YP_002038268.1 194398141 6480414 complement(1504038..1504739) 1 NC_011072.1 identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 1504739 6480414 SPG_1563 Streptococcus pneumoniae G54 ABC transporter ATP-binding protein YP_002038268.1 1504038 R 512566 CDS YP_002038269.1 194398489 6480635 complement(1504989..1507400) 1 NC_011072.1 hypothetical protein 1507400 6480635 SPG_1564 Streptococcus pneumoniae G54 hypothetical protein YP_002038269.1 1504989 R 512566 CDS YP_002038270.1 194396685 6479975 complement(1507453..1508145) 1 NC_011072.1 2,3-bisphosphoglycerate-dependent; catalyzes the interconversion of 2-phosphoglycerate to 3-phosphoglycerate; phosphoglyceromutase 1508145 gpmA 6479975 gpmA Streptococcus pneumoniae G54 phosphoglyceromutase YP_002038270.1 1507453 R 512566 CDS YP_002038271.1 194396946 6480272 complement(1508196..1508384) 1 NC_011072.1 hypothetical protein 1508384 6480272 SPG_1566 Streptococcus pneumoniae G54 hypothetical protein YP_002038271.1 1508196 R 512566 CDS YP_002038272.1 194397547 6479666 complement(1508680..1509042) 1 NC_011072.1 identified by glimmer; putative; hypothetical protein 1509042 6479666 SPG_1567 Streptococcus pneumoniae G54 hypothetical protein YP_002038272.1 1508680 R 512566 CDS YP_002038273.1 194398241 6479098 complement(1509451..1512243) 1 NC_011072.1 IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase family type 1 subfamily; some organisms carry two different copies of this enzyme; isoleucyl-tRNA synthetase 1512243 ileS 6479098 ileS Streptococcus pneumoniae G54 isoleucyl-tRNA synthetase YP_002038273.1 1509451 R 512566 CDS YP_002038274.1 194397320 6479215 complement(1512496..1512612) 1 NC_011072.1 identified by glimmer; putative; hypothetical protein 1512612 6479215 SPG_1569 Streptococcus pneumoniae G54 hypothetical protein YP_002038274.1 1512496 R 512566 CDS YP_002038275.1 194397163 6480461 complement(1512591..1513379) 1 NC_011072.1 identified by match to protein family HMM PF05103; cell division protein DivIVA 1513379 6480461 SPG_1570 Streptococcus pneumoniae G54 cell division protein DivIVA YP_002038275.1 1512591 R 512566 CDS YP_002038276.1 194398742 6479135 complement(1513388..1514173) 1 NC_011072.1 identified by match to protein family HMM PF01479; YlmH protein 1514173 6479135 SPG_1571 Streptococcus pneumoniae G54 YlmH protein YP_002038276.1 1513388 R 512566 CDS YP_002038277.1 194398065 6479212 complement(1514170..1514433) 1 NC_011072.1 identified by match to protein family HMM PF02325; YlmG protein 1514433 6479212 SPG_1572 Streptococcus pneumoniae G54 YlmG protein YP_002038277.1 1514170 R 512566 CDS YP_002038278.1 194397607 6479619 complement(1514433..1514972) 1 NC_011072.1 identified by match to protein family HMM PF04472; YlmF protein 1514972 6479619 SPG_1573 Streptococcus pneumoniae G54 YlmF protein YP_002038278.1 1514433 R 512566 CDS YP_002038279.1 194397968 6479050 complement(1514982..1515653) 1 NC_011072.1 identified by match to protein family HMM TIGR00044; YlmE protein 1515653 6479050 SPG_1574 Streptococcus pneumoniae G54 YlmE protein YP_002038279.1 1514982 R 512566 CDS YP_002038280.1 194398629 6479589 complement(1515658..1516917) 1 NC_011072.1 GTPase; similar structure to tubulin; forms ring-shaped polymers at the site of cell division; other proteins such as FtsA, ZipA, and ZapA, interact with and regulate FtsZ function; cell division protein FtsZ 1516917 ftsZ 6479589 ftsZ Streptococcus pneumoniae G54 cell division protein FtsZ YP_002038280.1 1515658 R 512566 CDS YP_002038281.1 194396784 6479621 complement(1516934..1518307) 1 NC_011072.1 identified by match to protein family HMM PF02491; match to protein family HMM TIGR01174; cell division protein FtsA 1518307 ftsA 6479621 ftsA Streptococcus pneumoniae G54 cell division protein FtsA YP_002038281.1 1516934 R 512566 CDS YP_002038282.1 194397392 6479917 complement(1518526..1519230) 1 NC_011072.1 identified by glimmer; putative; hypothetical protein 1519230 6479917 SPG_1577 Streptococcus pneumoniae G54 hypothetical protein YP_002038282.1 1518526 R 512566 CDS YP_002038283.1 194397509 6480490 complement(1519321..1519932) 1 NC_011072.1 identified by match to protein family HMM PF00293; MutT/nudix family protein 1519932 6480490 SPG_1578 Streptococcus pneumoniae G54 MutT/nudix family protein YP_002038283.1 1519321 R 512566 CDS YP_002038284.1 194396936 6479232 complement(1519919..1521292) 1 NC_011072.1 identified by match to protein family HMM PF01225; match to protein family HMM PF02875; match to protein family HMM PF08245; match to protein family HMM TIGR01143; UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase 1521292 murF 6479232 murF Streptococcus pneumoniae G54 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase YP_002038284.1 1519919 R 512566 CDS YP_002038285.1 194397559 6479661 complement(1521376..1522419) 1 NC_011072.1 D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli; D-alanyl-alanine synthetase A 1522419 ddl 6479661 ddl Streptococcus pneumoniae G54 D-alanyl-alanine synthetase A YP_002038285.1 1521376 R 512566 CDS YP_002038286.1 194398154 6479311 complement(1522595..1523191) 1 NC_011072.1 involved in a recombinational process of DNA repair, independent of the recBC complex; recombination protein RecR 1523191 recR 6479311 recR Streptococcus pneumoniae G54 recombination protein RecR YP_002038286.1 1522595 R 512566 CDS YP_002038287.1 194398674 6480334 complement(1523202..1525259) 1 NC_011072.1 identified by match to protein family HMM PF00905; match to protein family HMM PF03717; penicillin-binding protein 2B 1525259 6480334 SPG_1582 Streptococcus pneumoniae G54 penicillin-binding protein 2B YP_002038287.1 1523202 R 512566 CDS YP_002038288.1 194396775 6478760 1525459..1526310 1 NC_011072.1 identified by match to protein family HMM PF01380; match to protein family HMM PF01418; phosphosugar-binding transcriptional regulator 1526310 6478760 SPG_1583 Streptococcus pneumoniae G54 phosphosugar-binding transcriptional regulator YP_002038288.1 1525459 D 512566 CDS YP_002038289.1 194397437 6479734 complement(1526326..1527210) 1 NC_011072.1 identified by match to protein family HMM PF00480; glucokinase 1527210 6479734 SPG_1584 Streptococcus pneumoniae G54 glucokinase YP_002038289.1 1526326 R 512566 CDS YP_002038290.1 194397748 6480729 complement(1527228..1528145) 1 NC_011072.1 Steenbergen, S.M.: J Bacteriol. 2006 Sep;188(17):6195-206.; identified by match to protein family HMM PF00701; N-acetylneuraminate lyase 1528145 6480729 SPG_1585 Streptococcus pneumoniae G54 N-acetylneuraminate lyase YP_002038290.1 1527228 R 512566 CDS YP_002038291.1 194398006 6480718 complement(1528314..1528958) 1 NC_011072.1 identified by match to protein family HMM PF04854; hypothetical protein 1528958 6480718 SPG_1586 Streptococcus pneumoniae G54 hypothetical protein YP_002038291.1 1528314 R 512566 CDS YP_002038292.1 194396822 6479023 complement(1529244..1529378) 1 NC_011072.1 hypothetical protein 1529378 6479023 SPG_1587 Streptococcus pneumoniae G54 hypothetical protein YP_002038292.1 1529244 R 512566 CDS YP_002038293.1 194397169 6479409 complement(1529694..1530146) 1 NC_011072.1 identified by match to protein family HMM PF04074; match to protein family HMM TIGR00022; hypothetical protein 1530146 6479409 SPG_1588 Streptococcus pneumoniae G54 hypothetical protein YP_002038293.1 1529694 R 512566 CDS YP_002038294.1 194397708 6479539 complement(1530419..1531258) 1 NC_011072.1 identified by match to protein family HMM PF00528; ABC transporter permease 1531258 6479539 SPG_1589 Streptococcus pneumoniae G54 ABC transporter permease YP_002038294.1 1530419 R 512566 CDS YP_002038295.1 194397098 6480057 complement(1531274..1532161) 1 NC_011072.1 identified by match to protein family HMM PF00528; ABC transporter permease 1532161 6480057 SPG_1590 Streptococcus pneumoniae G54 ABC transporter permease YP_002038295.1 1531274 R 512566 CDS YP_002038296.1 194398623 6480073 complement(1532393..1533721) 1 NC_011072.1 identified by match to protein family HMM PF01547; ABC transporter substrate binding protein 1533721 6480073 SPG_1591 Streptococcus pneumoniae G54 ABC transporter substrate binding protein YP_002038296.1 1532393 R 512566 CDS YP_002038297.1 194398486 6479532 complement(1533846..1535363) 1 NC_011072.1 identified by match to protein family HMM PF00367; match to protein family HMM PF02378; match to protein family HMM TIGR00826; PTS system transporter subunit IIBC 1535363 6479532 SPG_1592 Streptococcus pneumoniae G54 PTS system transporter subunit IIBC YP_002038297.1 1533846 R 512566 CDS YP_002038298.1 194398731 6480608 complement(1535382..1536080) 1 NC_011072.1 Converts N-acetylmannosamine-6-phosphate to N-acetylglucosamine-6-phosphate; N-acetylmannosamine-6-phosphate 2-epimerase 1536080 nanE 6480608 nanE Streptococcus pneumoniae G54 N-acetylmannosamine-6-phosphate 2-epimerase YP_002038298.1 1535382 R 512566 CDS YP_002038299.1 194397306 6478977 complement(1536254..1537357) 1 NC_011072.1 identified by match to protein family HMM PF01118; match to protein family HMM PF01408; match to protein family HMM PF02894; match to protein family HMM PF03447; oxidoreductase 1537357 6478977 SPG_1594 Streptococcus pneumoniae G54 oxidoreductase YP_002038299.1 1536254 R 512566 CDS YP_002038300.1 194396849 6478703 complement(1537369..1539462) 1 NC_011072.1 identified by match to protein family HMM PF02012; match to protein family HMM PF02973; neuraminidase B 1539462 nanB 6478703 nanB Streptococcus pneumoniae G54 neuraminidase B YP_002038300.1 1537369 R 512566 CDS YP_002038301.1 194398530 6478640 complement(1539480..1540313) 1 NC_011072.1 identified by match to protein family HMM PF00528; ABC transporter permease 1540313 6478640 SPG_1596 Streptococcus pneumoniae G54 ABC transporter permease YP_002038301.1 1539480 R 512566 CDS YP_002038302.1 194398046 6480007 complement(1540313..1541197) 1 NC_011072.1 identified by match to protein family HMM PF00528; ABC transporter permease 1541197 6480007 SPG_1597 Streptococcus pneumoniae G54 ABC transporter permease YP_002038302.1 1540313 R 512566 CDS YP_002038303.1 194396878 6479479 complement(1541276..1542613) 1 NC_011072.1 identified by match to protein family HMM PF01547; ABC transporter substrate-binding protein 1542613 6479479 SPG_1598 Streptococcus pneumoniae G54 ABC transporter substrate-binding protein YP_002038303.1 1541276 R 512566 CDS YP_002038304.1 194397793 6478808 complement(1542632..1543084) 1 NC_011072.1 identified by match to protein family HMM PF04074; match to protein family HMM TIGR00022; hypothetical protein 1543084 6478808 SPG_1599 Streptococcus pneumoniae G54 hypothetical protein YP_002038304.1 1542632 R 512566 CDS YP_002038305.1 194397355 6479746 complement(1544100..1546928) 1 NC_011072.1 identified by match to protein family HMM PF02012; match to protein family HMM PF02973; match to protein family HMM TIGR01167; neuraminidase A 1546928 nanA 6479746 nanA Streptococcus pneumoniae G54 neuraminidase A YP_002038305.1 1544100 R 512566 CDS YP_002038306.1 194396854 6479987 complement(1547286..1547513) 1 NC_011072.1 hypothetical protein 1547513 6479987 SPG_1601 Streptococcus pneumoniae G54 hypothetical protein YP_002038306.1 1547286 R 512566 CDS YP_002038307.1 194397386 6479347 complement(1548408..1549388) 1 NC_011072.1 identified by match to protein family HMM PF05448; xylan esterase 1 1549388 axe1 6479347 axe1 Streptococcus pneumoniae G54 xylan esterase 1 YP_002038307.1 1548408 R 512566 CDS YP_002038308.1 194396798 6480559 complement(1549704..1551719) 1 NC_011072.1 catalyzes branch migration in Holliday junction intermediates; ATP-dependent DNA helicase RecG 1551719 recG 6480559 recG Streptococcus pneumoniae G54 ATP-dependent DNA helicase RecG YP_002038308.1 1549704 R 512566 CDS YP_002038309.1 194398697 6479457 complement(1551738..1552841) 1 NC_011072.1 converts L-alanine to D-alanine which is used in cell wall biosynthesis; binds one pyridoxal phosphate per monomer; forms a homodimer; alanine racemase 1552841 alr 6479457 alr Streptococcus pneumoniae G54 alanine racemase YP_002038309.1 1551738 R 512566 CDS YP_002038310.1 194398007 6479104 complement(1552831..1553193) 1 NC_011072.1 Catalyzes the formation of holo-ACP, which mediates the essential transfer of acyl fatty acid intermediates during the biosynthesis of fatty acids and lipids; 4'-phosphopantetheinyl transferase 1553193 acpS 6479104 acpS Streptococcus pneumoniae G54 4'-phosphopantetheinyl transferase YP_002038310.1 1552831 R 512566 CDS YP_002038311.1 194396711 6479024 complement(1553238..1554269) 1 NC_011072.1 catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, phenylalanine sensitive; phospho-2-dehydro-3-deoxyheptonate aldolase 1554269 6479024 SPG_1606 Streptococcus pneumoniae G54 phospho-2-dehydro-3-deoxyheptonate aldolase YP_002038311.1 1553238 R 512566 CDS YP_002038312.1 194397175 6480293 complement(1554271..1555302) 1 NC_011072.1 catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, tyrosine sensitive; phospho-2-dehydro-3-deoxyheptonate aldolase 1555302 6480293 SPG_1607 Streptococcus pneumoniae G54 phospho-2-dehydro-3-deoxyheptonate aldolase YP_002038312.1 1554271 R 512566 CDS YP_002038313.1 194397932 6478992 complement(1555383..1557896) 1 NC_011072.1 functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond SecA1; SecA2 is not essential and seems to play a role in secretion of a subset of proteins; preprotein translocase subunit SecA 1557896 secA 6478992 secA Streptococcus pneumoniae G54 preprotein translocase subunit SecA YP_002038313.1 1555383 R 512566 CDS YP_002038314.1 194398498 6478669 complement(1558042..1558329) 1 NC_011072.1 hypothetical protein 1558329 6478669 SPG_1609 Streptococcus pneumoniae G54 hypothetical protein YP_002038314.1 1558042 R 512566 CDS YP_002038315.1 194398753 6480765 complement(1558340..1558990) 1 NC_011072.1 identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 1558990 6480765 SPG_1610 Streptococcus pneumoniae G54 ABC transporter ATP-binding protein YP_002038315.1 1558340 R 512566 CDS YP_002038316.1 194397076 6479248 complement(1558994..1559635) 1 NC_011072.1 hypothetical protein 1559635 6479248 SPG_1611 Streptococcus pneumoniae G54 hypothetical protein YP_002038316.1 1558994 R 512566 CDS YP_002038317.1 194396859 6480319 complement(1559628..1560419) 1 NC_011072.1 identified by glimmer; putative; hypothetical protein 1560419 6480319 SPG_1612 Streptococcus pneumoniae G54 hypothetical protein YP_002038317.1 1559628 R 512566 CDS YP_002038318.1 194397556 6479421 complement(1560604..1560939) 1 NC_011072.1 hypothetical protein 1560939 6479421 SPG_1613 Streptococcus pneumoniae G54 hypothetical protein YP_002038318.1 1560604 R 512566 CDS YP_002038319.1 194397847 6478798 complement(1561079..1561414) 1 NC_011072.1 hypothetical protein 1561414 6478798 SPG_1614 Streptococcus pneumoniae G54 hypothetical protein YP_002038319.1 1561079 R 512566 CDS YP_002038320.1 194398265 6480442 complement(1561502..1562812) 1 NC_011072.1 EngA; essential Neisserial GTPase; synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains; GTP-binding protein EngA 1562812 engA 6480442 engA Streptococcus pneumoniae G54 GTP-binding protein EngA YP_002038320.1 1561502 R 512566 CDS YP_002038321.1 194397087 6479590 complement(1562826..1563539) 1 NC_011072.1 identified by match to protein family HMM PF00881; nitroreductase family protein 1563539 6479590 SPG_1616 Streptococcus pneumoniae G54 nitroreductase family protein YP_002038321.1 1562826 R 512566 CDS YP_002038322.1 194397852 6480540 complement(1563536..1564432) 1 NC_011072.1 Primosomal protein that may act to load helicase DnaC during DNA replication; primosomal protein DnaI 1564432 6480540 SPG_1617 Streptococcus pneumoniae G54 primosomal protein DnaI YP_002038322.1 1563536 R 512566 CDS YP_002038323.1 194398048 6480140 complement(1564433..1565602) 1 NC_011072.1 identified by glimmer; putative; hypothetical protein 1565602 6480140 SPG_1618 Streptococcus pneumoniae G54 hypothetical protein YP_002038323.1 1564433 R 512566 CDS YP_002038324.1 194396972 6479481 complement(1565603..1566076) 1 NC_011072.1 identified by match to protein family HMM PF03477; match to protein family HMM TIGR00244; transcriptional regulator NrdR 1566076 nrdR 6479481 nrdR Streptococcus pneumoniae G54 transcriptional regulator NrdR YP_002038324.1 1565603 R 512566 CDS YP_002038325.1 194397575 6480316 1566216..1566581 1 NC_011072.1 identified by match to protein family HMM PF00392; regulatory protein, GntR 1566581 6480316 SPG_1620 Streptococcus pneumoniae G54 regulatory protein, GntR YP_002038325.1 1566216 D 512566 CDS YP_002038326.1 194398220 6478821 1566586..1567281 1 NC_011072.1 identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 1567281 6478821 SPG_1621 Streptococcus pneumoniae G54 ABC transporter ATP-binding protein YP_002038326.1 1566586 D 512566 CDS YP_002038327.1 194398173 6479258 1567298..1568065 1 NC_011072.1 ABC transporter ATP-binding protein 1568065 6479258 SPG_1622 Streptococcus pneumoniae G54 ABC transporter ATP-binding protein YP_002038327.1 1567298 D 512566 CDS YP_002038328.1 194398714 6480734 complement(1568418..1569617) 1 NC_011072.1 ABC transporter permease 1569617 6480734 SPG_1623 Streptococcus pneumoniae G54 ABC transporter permease YP_002038328.1 1568418 R 512566 CDS YP_002038329.1 194396656 6479553 complement(1569614..1570507) 1 NC_011072.1 identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 1570507 6479553 SPG_1624 Streptococcus pneumoniae G54 ABC transporter ATP-binding protein YP_002038329.1 1569614 R 512566 CDS YP_002038330.1 194397002 6479662 1571817..1572434 1 NC_011072.1 identified by match to protein family HMM PF09335; hypothetical protein 1572434 6479662 SPG_1625 Streptococcus pneumoniae G54 hypothetical protein YP_002038330.1 1571817 D 512566 CDS YP_002038331.1 194397493 6479794 complement(1572477..1573364) 1 NC_011072.1 identified by match to protein family HMM PF00480; fructokinase 1573364 6479794 SPG_1626 Streptococcus pneumoniae G54 fructokinase YP_002038331.1 1572477 R 512566 CDS YP_002038332.1 194398253 6480345 complement(1573513..1575396) 1 NC_011072.1 identified by match to protein family HMM PF00358; match to protein family HMM PF00367; match to protein family HMM PF02378; match to protein family HMM TIGR00826; match to protein family HMM TIGR00830; match to protein family HMM TIGR01996; PTS system transporter subunit IIBCA 1575396 6480345 SPG_1627 Streptococcus pneumoniae G54 PTS system transporter subunit IIBCA YP_002038332.1 1573513 R 512566 CDS YP_002038333.1 194398151 6479280 complement(1575523..1575720) 1 NC_011072.1 hypothetical protein 1575720 6479280 SPG_1628 Streptococcus pneumoniae G54 hypothetical protein YP_002038333.1 1575523 R 512566 CDS YP_002038334.1 194397540 6480465 1575773..1577227 1 NC_011072.1 identified by match to protein family HMM PF00251; match to protein family HMM PF08244; match to protein family HMM TIGR01322; sucrose-6-phosphate hydrolase 1577227 6480465 SPG_1629 Streptococcus pneumoniae G54 sucrose-6-phosphate hydrolase YP_002038334.1 1575773 D 512566 CDS YP_002038335.1 194397007 6479127 1577208..1578173 1 NC_011072.1 identified by match to protein family HMM PF00356; match to protein family HMM PF00532; sucrose operon repressor 1578173 6479127 SPG_1630 Streptococcus pneumoniae G54 sucrose operon repressor YP_002038335.1 1577208 D 512566 CDS YP_002038336.1 194398005 6480043 complement(1578208..1579482) 1 NC_011072.1 identified by match to protein family HMM TIGR00532; 3-hydroxy-3-methylglutaryl-coenzyme a reductase 1579482 mvaA 6480043 mvaA Streptococcus pneumoniae G54 3-hydroxy-3-methylglutaryl-coenzyme a reductase YP_002038336.1 1578208 R 512566 CDS YP_002038337.1 194397436 6479413 complement(1579482..1580678) 1 NC_011072.1 Wilding, et. al. (2000) J. Bacteriol. 182, 4319-4327]; identified by match to protein family HMM PF01154; match to protein family HMM PF08540; match to protein family HMM TIGR01835; HMG-CoA synthase 1580678 mvaS 6479413 mvaS Streptococcus pneumoniae G54 HMG-CoA synthase YP_002038337.1 1579482 R 512566 CDS YP_002038338.1 194396815 6480728 complement(1580785..1580982) 1 NC_011072.1 hypothetical protein 1580982 6480728 SPG_1633 Streptococcus pneumoniae G54 hypothetical protein YP_002038338.1 1580785 R 512566 CDS YP_002038339.1 194398366 6478794 complement(1581101..1581721) 1 NC_011072.1 identified by match to protein family HMM PF01609; transposase 1581721 6478794 SPG_1634 Streptococcus pneumoniae G54 transposase YP_002038339.1 1581101 R 512566 CDS YP_002038340.1 194397205 6480069 complement(1581786..1582235) 1 NC_011072.1 hypothetical protein 1582235 6480069 SPG_1635 Streptococcus pneumoniae G54 hypothetical protein YP_002038340.1 1581786 R 512566 CDS YP_002038341.1 194396710 6480039 complement(1582237..1582995) 1 NC_011072.1 identified by match to protein family HMM PF06738; hypothetical protein 1582995 6480039 SPG_1636 Streptococcus pneumoniae G54 hypothetical protein YP_002038341.1 1582237 R 512566 CDS YP_002038342.1 194397063 6480741 complement(1583110..1584741) 1 NC_011072.1 contains potential frameshift; identified by match to protein family HMM PF00069; match to protein family HMM PF03793; serine/threonine protein kinase 1584741 6480741 SPG_1637 Streptococcus pneumoniae G54 serine/threonine protein kinase YP_002038342.1 1583110 R 512566 CDS YP_002038343.1 194398725 6479788 complement(1584761..1585090) 1 NC_011072.1 contains potential frameshift; serine/threonine protein kinase 1585090 6479788 SPG_1638 Streptococcus pneumoniae G54 serine/threonine protein kinase YP_002038343.1 1584761 R 512566 CDS YP_002038344.1 194397863 6479382 complement(1585087..1585827) 1 NC_011072.1 identified by match to protein family HMM PF00481; protein phosphatase 2C 1585827 6479382 SPG_1639 Streptococcus pneumoniae G54 protein phosphatase 2C YP_002038344.1 1585087 R 512566 CDS YP_002038345.1 194397538 6480631 complement(1585842..1587155) 1 NC_011072.1 identified by match to protein family HMM PF01029; match to protein family HMM PF01189; match to protein family HMM TIGR00563; ribosomal RNA small subunit methyltransferase B 1587155 sun 6480631 sun Streptococcus pneumoniae G54 ribosomal RNA small subunit methyltransferase B YP_002038345.1 1585842 R 512566 CDS YP_002038346.1 194398296 6479396 complement(1587148..1588083) 1 NC_011072.1 modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet) which is important in translation initiation; inactivation of this gene in Escherichia coli severely impairs growth; methionyl-tRNA formyltransferase 1588083 fmt 6479396 fmt Streptococcus pneumoniae G54 methionyl-tRNA formyltransferase YP_002038346.1 1587148 R 512566 CDS YP_002038347.1 194397881 6479055 complement(1588096..1590492) 1 NC_011072.1 binding of PriA to forked DNA starts the assembly of the primosome, also possesses 3'-5' helicase activity; primosome assembly protein PriA 1590492 6479055 SPG_1642 Streptococcus pneumoniae G54 primosome assembly protein PriA YP_002038347.1 1588096 R 512566 CDS YP_002038348.1 194398149 6480362 complement(1590558..1590869) 1 NC_011072.1 Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits; DNA-directed RNA polymerase subunit omega 1590869 rpoZ 6480362 rpoZ Streptococcus pneumoniae G54 DNA-directed RNA polymerase subunit omega YP_002038348.1 1590558 R 512566 CDS YP_002038349.1 194396676 6480463 complement(1590897..1591523) 1 NC_011072.1 Essential for recycling GMP and indirectly, cGMP; guanylate kinase 1591523 gmk 6480463 gmk Streptococcus pneumoniae G54 guanylate kinase YP_002038349.1 1590897 R 512566 CDS YP_002038350.1 194398755 6479850 complement(1591653..1593266) 1 NC_011072.1 identified by match to protein family HMM PF00013; match to protein family HMM PF01966; match to protein family HMM TIGR00277; match to protein family HMM TIGR03319; hypothetical protein 1593266 6479850 SPG_1645 Streptococcus pneumoniae G54 hypothetical protein YP_002038350.1 1591653 R 512566 CDS YP_002038351.1 194398169 6480745 complement(1593610..1596357) 1 NC_011072.1 hypothetical protein 1596357 6480745 SPG_1646 Streptococcus pneumoniae G54 hypothetical protein YP_002038351.1 1593610 R 512566 CDS YP_002038352.1 194397585 6480206 complement(1596705..1597802) 1 NC_011072.1 identified by glimmer; putative; hypothetical protein 1597802 6480206 SPG_1647 Streptococcus pneumoniae G54 hypothetical protein YP_002038352.1 1596705 R 512566 CDS YP_002038353.1 194398143 6479161 complement(1597812..1598558) 1 NC_011072.1 identified by match to protein family HMM PF08241; match to protein family HMM PF08242; hypothetical protein 1598558 6479161 SPG_1648 Streptococcus pneumoniae G54 hypothetical protein YP_002038353.1 1597812 R 512566 CDS YP_002038354.1 194397957 6480567 complement(1598661..1599014) 1 NC_011072.1 identified by match to protein family HMM PF02410; match to protein family HMM TIGR00090; hypothetical protein 1599014 6480567 SPG_1649 Streptococcus pneumoniae G54 hypothetical protein YP_002038354.1 1598661 R 512566 CDS YP_002038355.1 194396935 6479525 complement(1599027..1599527) 1 NC_011072.1 isochorismatase family protein 1599527 6479525 SPG_1650 Streptococcus pneumoniae G54 isochorismatase family protein YP_002038355.1 1599027 R 512566 CDS YP_002038356.1 194398417 6479501 complement(1599528..1600121) 1 NC_011072.1 identified by match to protein family HMM PF01966; match to protein family HMM TIGR00488; hypothetical protein 1600121 6479501 SPG_1651 Streptococcus pneumoniae G54 hypothetical protein YP_002038356.1 1599528 R 512566 CDS YP_002038357.1 194398131 6480468 complement(1600121..1600750) 1 NC_011072.1 transfers an adenyl group from ATP to NaMN to form nicotinic acid adenine dinucleotide (NaAD) which is then converted to the ubiquitous compound NAD by NAD synthetase; essential enzyme in bacteria; nicotinic acid mononucleotide adenylyltransferase 1600750 nadD 6480468 nadD Streptococcus pneumoniae G54 nicotinic acid mononucleotide adenylyltransferase YP_002038357.1 1600121 R 512566 CDS YP_002038358.1 194397685 6480776 complement(1600802..1601113) 1 NC_011072.1 identified by match to protein family HMM PF01985; match to protein family HMM TIGR00253; hypothetical protein 1601113 6480776 SPG_1653 Streptococcus pneumoniae G54 hypothetical protein YP_002038358.1 1600802 R 512566 CDS YP_002038359.1 194396922 6478880 complement(1601327..1602433) 1 NC_011072.1 in Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis; GTP-binding protein YqeH 1602433 6478880 SPG_1654 Streptococcus pneumoniae G54 GTP-binding protein YqeH YP_002038359.1 1601327 R 512566 CDS YP_002038360.1 194398636 6480065 complement(1602436..1602963) 1 NC_011072.1 identified by match to protein family HMM TIGR01662; match to protein family HMM TIGR01668; had-superfamily hydrolase (subfamily IIIa) phosphatase 1602963 6480065 SPG_1655 Streptococcus pneumoniae G54 had-superfamily hydrolase (subfamily IIIa) phosphatase YP_002038360.1 1602436 R 512566 CDS YP_002038361.1 194398022 6479391 complement(1602978..1603886) 1 NC_011072.1 identified by match to protein family HMM PF01544; magnesium transporter, CorA family protein 1603886 6479391 SPG_1656 Streptococcus pneumoniae G54 magnesium transporter, CorA family protein YP_002038361.1 1602978 R 512566 CDS YP_002038362.1 194398419 6479336 complement(1603943..1604503) 1 NC_011072.1 identified by match to protein family HMM PF00924; small conductance mechanosensitive ion channel family protein 1604503 6479336 SPG_1657 Streptococcus pneumoniae G54 small conductance mechanosensitive ion channel family protein YP_002038362.1 1603943 R 512566 CDS YP_002038363.1 194397019 6480488 1604707..1604865 1 NC_011072.1 hypothetical protein 1604865 6480488 SPG_1658 Streptococcus pneumoniae G54 hypothetical protein YP_002038363.1 1604707 D 512566 CDS YP_002038364.1 194397681 6480192 1604891..1605850 1 NC_011072.1 involved in the import of serine and threonine coupled with the import of sodium; serine/threonine transporter SstT 1605850 6480192 SPG_1659 Streptococcus pneumoniae G54 serine/threonine transporter SstT YP_002038364.1 1604891 D 512566 CDS YP_002038365.1 194398182 6478740 1605918..1606871 1 NC_011072.1 identified by match to protein family HMM PF06081; hypothetical protein 1606871 6478740 SPG_1660 Streptococcus pneumoniae G54 hypothetical protein YP_002038365.1 1605918 D 512566 CDS YP_002038366.1 194397850 6480546 1607016..1607396 1 NC_011072.1 identified by match to protein family HMM PF01047; MarR family transcriptional regulator 1607396 6480546 SPG_1661 Streptococcus pneumoniae G54 MarR family transcriptional regulator YP_002038366.1 1607016 D 512566 CDS YP_002038367.1 194398315 6480124 1607495..1607716 1 NC_011072.1 hypothetical protein 1607716 6480124 SPG_1662 Streptococcus pneumoniae G54 hypothetical protein YP_002038367.1 1607495 D 512566 CDS YP_002038368.1 194396881 6479238 1607733..1608047 1 NC_011072.1 identified by match to protein family HMM PF00085; match to protein family HMM TIGR01068; thioredoxin 1608047 trx 6479238 trx Streptococcus pneumoniae G54 thioredoxin YP_002038368.1 1607733 D 512566 CDS YP_002038369.1 194397564 6478724 1608352..1608885 1 NC_011072.1 NADPH-dependent; catalyzes the reduction of 7-cyano-7-deazaguanine to 7-aminomethyl-7-deazaguanine in queuosine biosynthesis; 7-cyano-7-deazaguanine reductase 1608885 6478724 SPG_1664 Streptococcus pneumoniae G54 7-cyano-7-deazaguanine reductase YP_002038369.1 1608352 D 512566 CDS YP_002038370.1 194397717 6479189 complement(1609229..1609861) 1 NC_011072.1 identified by match to protein family HMM PF00230; aquaporin 1609861 6479189 SPG_1665 Streptococcus pneumoniae G54 aquaporin YP_002038370.1 1609229 R 512566 CDS YP_002038371.1 194396934 6480791 complement(1610007..1610798) 1 NC_011072.1 hypothetical protein 1610798 6480791 SPG_1666 Streptococcus pneumoniae G54 hypothetical protein YP_002038371.1 1610007 R 512566 CDS YP_002038372.1 194397899 6479935 complement(1610866..1611021) 1 NC_011072.1 identified by glimmer; putative; hypothetical protein 1611021 6479935 SPG_1667 Streptococcus pneumoniae G54 hypothetical protein YP_002038372.1 1610866 R 512566 CDS YP_002038373.1 194398469 6478812 complement(1611044..1612840) 1 NC_011072.1 identified by match to protein family HMM PF01432; match to protein family HMM PF08439; match to protein family HMM TIGR00181; oligoendopeptidase F 1612840 6478812 SPG_1668 Streptococcus pneumoniae G54 oligoendopeptidase F YP_002038373.1 1611044 R 512566 CDS YP_002038374.1 194396708 6480676 complement(1612851..1613594) 1 NC_011072.1 in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA; cells lacking this function can grow, but are outcompeted by wild-type; SAM-dependent m(3)U1498 methyltransferase; 16S ribosomal RNA methyltransferase RsmE 1613594 6480676 SPG_1669 Streptococcus pneumoniae G54 16S ribosomal RNA methyltransferase RsmE YP_002038374.1 1612851 R 512566 CDS YP_002038375.1 194397254 6479852 complement(1613596..1613862) 1 NC_011072.1 contains potential frameshift; ribosomal protein L11 methyltransferase 1613862 6479852 SPG_1670 Streptococcus pneumoniae G54 ribosomal protein L11 methyltransferase YP_002038375.1 1613596 R 512566 CDS YP_002038376.1 194398145 6478736 complement(1613855..1614550) 1 NC_011072.1 contains potential frameshift; identified by match to protein family HMM PF06325; ribosomal protein L11 methyltransferase 1614550 6478736 SPG_1671 Streptococcus pneumoniae G54 ribosomal protein L11 methyltransferase YP_002038376.1 1613855 R 512566 CDS YP_002038377.1 194398538 6480569 complement(1614685..1615113) 1 NC_011072.1 identified by match to protein family HMM PF00293; MutT/nudix family protein 1615113 6480569 SPG_1672 Streptococcus pneumoniae G54 MutT/nudix family protein YP_002038377.1 1614685 R 512566 CDS YP_002038378.1 194397129 6480537 complement(1615094..1616182) 1 NC_011072.1 identified by glimmer; putative; hypothetical protein 1616182 6480537 SPG_1673 Streptococcus pneumoniae G54 hypothetical protein YP_002038378.1 1615094 R 512566 CDS YP_002038379.1 194397869 6480082 complement(1616201..1616671) 1 NC_011072.1 identified by glimmer; putative; hypothetical protein 1616671 6480082 SPG_1674 Streptococcus pneumoniae G54 hypothetical protein YP_002038379.1 1616201 R 512566 CDS YP_002038380.1 194398053 6480254 complement(1616962..1617414) 1 NC_011072.1 identified by match to protein family HMM PF03681; hypothetical protein 1617414 6480254 SPG_1675 Streptococcus pneumoniae G54 hypothetical protein YP_002038380.1 1616962 R 512566 CDS YP_002038381.1 194397600 6478690 complement(1617451..1617630) 1 NC_011072.1 identified by match to protein family HMM PF07927; hypothetical protein 1617630 6478690 SPG_1676 Streptococcus pneumoniae G54 hypothetical protein YP_002038381.1 1617451 R 512566 CDS YP_002038382.1 194398077 6479344 complement(1617767..1617946) 1 NC_011072.1 hypothetical protein 1617946 6479344 SPG_1677 Streptococcus pneumoniae G54 hypothetical protein YP_002038382.1 1617767 R 512566 CDS YP_002038383.1 194396669 6479005 complement(1618150..1618350) 1 NC_011072.1 hypothetical protein 1618350 6479005 SPG_1678 Streptococcus pneumoniae G54 hypothetical protein YP_002038383.1 1618150 R 512566 CDS YP_002038384.1 194397127 6479752 1618620..1619891 1 NC_011072.1 identified by match to protein family HMM PF00004; recombination factor protein RarA 1619891 6479752 SPG_1679 Streptococcus pneumoniae G54 recombination factor protein RarA YP_002038384.1 1618620 D 512566 CDS YP_002038385.1 194397978 6478980 complement(1620438..1621757) 1 NC_011072.1 identified by match to protein family HMM PF00251; match to protein family HMM TIGR01322; sucrose-6-phosphate hydrolase 1621757 6478980 SPG_1681 Streptococcus pneumoniae G54 sucrose-6-phosphate hydrolase YP_002038385.1 1620438 R 512566 CDS YP_002038386.1 194398449 6479061 complement(1621767..1622612) 1 NC_011072.1 identified by match to protein family HMM PF00528; ABC transporter permease 1622612 6479061 SPG_1682 Streptococcus pneumoniae G54 ABC transporter permease YP_002038386.1 1621767 R 512566 CDS YP_002038387.1 194397018 6480126 complement(1622614..1623516) 1 NC_011072.1 identified by match to protein family HMM PF00528; ABC transporter permease 1623516 6480126 SPG_1683 Streptococcus pneumoniae G54 ABC transporter permease YP_002038387.1 1622614 R 512566 CDS YP_002038388.1 194397613 6479717 complement(1623612..1624922) 1 NC_011072.1 identified by match to protein family HMM PF01547; ABC transporter substrate-binding protein 1624922 6479717 SPG_1684 Streptococcus pneumoniae G54 ABC transporter substrate-binding protein YP_002038388.1 1623612 R 512566 CDS YP_002038389.1 194397926 6478933 complement(1625050..1626045) 1 NC_011072.1 identified by match to protein family HMM PF00356; match to protein family HMM PF00532; sucrose operon repressor 1626045 6478933 SPG_1685 Streptococcus pneumoniae G54 sucrose operon repressor YP_002038389.1 1625050 R 512566 CDS YP_002038390.1 194398533 6478782 complement(1626407..1627888) 1 NC_011072.1 Hemsley, C.; 2003 J. Bact, 22:6640-6647; identified by match to protein family HMM PF05043; match to protein family HMM PF08270; match to protein family HMM PF08279; match to protein family HMM PF08280; Mga-like repressor A MgrA 1627888 mgrA 6478782 mgrA Streptococcus pneumoniae G54 Mga-like repressor A MgrA YP_002038390.1 1626407 R 512566 CDS YP_002038391.1 194397822 6480284 1628331..1628495 1 NC_011072.1 identified by match to protein family HMM PF04226; hypothetical protein 1628495 6480284 SPG_1687 Streptococcus pneumoniae G54 hypothetical protein YP_002038391.1 1628331 D 512566 CDS YP_002038392.1 194398427 6480821 1628579..1629145 1 NC_011072.1 hypothetical protein 1629145 6480821 SPG_1688 Streptococcus pneumoniae G54 hypothetical protein YP_002038392.1 1628579 D 512566 CDS YP_002038393.1 194398313 6480248 1629157..1629327 1 NC_011072.1 hypothetical protein 1629327 6480248 SPG_1689 Streptococcus pneumoniae G54 hypothetical protein YP_002038393.1 1629157 D 512566 CDS YP_002038394.1 194396758 6479236 1629366..1629974 1 NC_011072.1 identified by match to protein family HMM PF03780; hypothetical protein 1629974 6479236 SPG_1690 Streptococcus pneumoniae G54 hypothetical protein YP_002038394.1 1629366 D 512566 CDS YP_002038395.1 194397636 6480493 1630005..1630208 1 NC_011072.1 identified by match to protein family HMM PF05532; hypothetical protein 1630208 6480493 SPG_1691 Streptococcus pneumoniae G54 hypothetical protein YP_002038395.1 1630005 D 512566 CDS YP_002038396.1 194398101 6479144 complement(1631022..1631141) 1 NC_011072.1 identified by glimmer; putative; hypothetical protein 1631141 6479144 SPG_1692 Streptococcus pneumoniae G54 hypothetical protein YP_002038396.1 1631022 R 512566 CDS YP_002038397.1 194398014 6480510 complement(1631359..1632129) 1 NC_011072.1 identified by glimmer; putative; hypothetical protein 1632129 6480510 SPG_1693 Streptococcus pneumoniae G54 hypothetical protein YP_002038397.1 1631359 R 512566 CDS YP_002038398.1 194396886 6479271 complement(1632144..1632770) 1 NC_011072.1 identified by match to protein family HMM PF03781; hypothetical protein 1632770 6479271 SPG_1694 Streptococcus pneumoniae G54 hypothetical protein YP_002038398.1 1632144 R 512566 CDS YP_002038399.1 194397334 6479466 complement(1632676..1633026) 1 NC_011072.1 contains potential frameshift; PTS system transporter subunit IIC 1633026 6479466 SPG_1695 Streptococcus pneumoniae G54 PTS system transporter subunit IIC YP_002038399.1 1632676 R 512566 CDS YP_002038400.1 194397800 6479909 complement(1632980..1633279) 1 NC_011072.1 contains potential frameshift; PTS system transporter subunit IIC 1633279 6479909 SPG_1696 Streptococcus pneumoniae G54 PTS system transporter subunit IIC YP_002038400.1 1632980 R 512566 CDS YP_002038401.1 194398264 6479922 complement(1633289..1633606) 1 NC_011072.1 identified by match to protein family HMM PF02255; PTS system transporter subunit IIA 1633606 6479922 SPG_1697 Streptococcus pneumoniae G54 PTS system transporter subunit IIA YP_002038401.1 1633289 R 512566 CDS YP_002038402.1 194398691 6479420 complement(1633623..1633940) 1 NC_011072.1 identified by match to protein family HMM PF02302; PTS system transporter subunit IIB 1633940 6479420 SPG_1698 Streptococcus pneumoniae G54 PTS system transporter subunit IIB YP_002038402.1 1633623 R 512566 CDS YP_002038403.1 194396675 6479432 complement(1633955..1634557) 1 NC_011072.1 contains potential frameshift; hypothetical protein 1634557 6479432 SPG_1699 Streptococcus pneumoniae G54 hypothetical protein YP_002038403.1 1633955 R 512566 CDS YP_002038404.1 194398491 6479810 complement(1634544..1634852) 1 NC_011072.1 contains potential frameshift; hypothetical protein 1634852 6479810 SPG_1700 Streptococcus pneumoniae G54 hypothetical protein YP_002038404.1 1634544 R 512566 CDS YP_002038405.1 194397905 6480368 complement(1634855..1636117) 1 NC_011072.1 identified by match to protein family HMM PF02378; match to protein family HMM TIGR00410; PTS system transporter subunit IIC 1636117 6480368 SPG_1701 Streptococcus pneumoniae G54 PTS system transporter subunit IIC YP_002038405.1 1634855 R 512566 CDS YP_002038406.1 194397546 6479513 1636397..1637575 1 NC_011072.1 identified by match to protein family HMM PF00480; transcriptional regulator/sugar kinase 1637575 6479513 SPG_1702 Streptococcus pneumoniae G54 transcriptional regulator/sugar kinase YP_002038406.1 1636397 D 512566 CDS YP_002038407.1 194397140 6479097 complement(1637803..1638249) 1 NC_011072.1 identified by match to protein family HMM PF00583; GNAT family acetyltransferase 1638249 6479097 SPG_1703 Streptococcus pneumoniae G54 GNAT family acetyltransferase YP_002038407.1 1637803 R 512566 CDS YP_002038408.1 194398693 6479930 1638319..1638978 1 NC_011072.1 identified by match to protein family HMM PF01478; match to protein family HMM PF06750; type 4 prepilin peptidase 1638978 6479930 SPG_1704 Streptococcus pneumoniae G54 type 4 prepilin peptidase YP_002038408.1 1638319 D 512566 CDS YP_002038409.1 194397247 6479434 complement(1639030..1640181) 1 NC_011072.1 identified by match to protein family HMM PF01381; match to protein family HMM PF06114; transcriptional regulator 1640181 6479434 SPG_1705 Streptococcus pneumoniae G54 transcriptional regulator YP_002038409.1 1639030 R 512566 CDS YP_002038410.1 194396692 6480377 complement(1640196..1640927) 1 NC_011072.1 hypothetical protein 1640927 6480377 SPG_1706 Streptococcus pneumoniae G54 hypothetical protein YP_002038410.1 1640196 R 512566 CDS YP_002038411.1 194397318 6479832 complement(1641229..1642005) 1 NC_011072.1 catalyzes the formation of indole and glyceraldehyde 3-phosphate from indoleglycerol phosphate in tryptophan biosynthesis; tryptophan synthase subunit alpha 1642005 trpA 6479832 trpA Streptococcus pneumoniae G54 tryptophan synthase subunit alpha YP_002038411.1 1641229 R 512566 CDS YP_002038412.1 194396868 6480424 complement(1641998..1643221) 1 NC_011072.1 catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate; tryptophan synthase subunit beta 1643221 trpB 6480424 trpB Streptococcus pneumoniae G54 tryptophan synthase subunit beta YP_002038412.1 1641998 R 512566 CDS YP_002038413.1 194398398 6479550 complement(1643199..1643798) 1 NC_011072.1 catalyzes the formation of 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate from N-(5-phospho-beta-D-ribosyl)-anthranilate in tryptophan biosynthesis; N-(5'-phosphoribosyl)anthranilate isomerase 1643798 trpF 6479550 trpF Streptococcus pneumoniae G54 N-(5'-phosphoribosyl)anthranilate isomerase YP_002038413.1 1643199 R 512566 CDS YP_002038414.1 194397867 6478899 complement(1643785..1644552) 1 NC_011072.1 involved in tryptophan biosynthesis; amino acid biosynthesis; converts 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate to C(1)-(3-indolyl)-glycerol 3-phosphate and carbon dioxide and water; indole-3-glycerol-phosphate synthase 1644552 trpC 6478899 trpC Streptococcus pneumoniae G54 indole-3-glycerol-phosphate synthase YP_002038414.1 1643785 R 512566 CDS YP_002038415.1 194397249 6480598 complement(1644549..1645553) 1 NC_011072.1 Catalyzes the conversion of N-(5-phospho-D-ribosyl)-anthranilate and diphosphate to anthranilate and 5-phospho-alpha-D-ribose 1-diphosphate; anthranilate phosphoribosyltransferase 1645553 trpD 6480598 trpD Streptococcus pneumoniae G54 anthranilate phosphoribosyltransferase YP_002038415.1 1644549 R 512566 CDS YP_002038416.1 194397176 6480379 complement(1645564..1646130) 1 NC_011072.1 TrpG; with TrpE catalyzes the formation of anthranilate and glutamate from chorismate and glutamine; TrpG provides the glutamine amidotransferase activity; anthranilate synthase component II 1646130 trpG 6480379 trpG Streptococcus pneumoniae G54 anthranilate synthase component II YP_002038416.1 1645564 R 512566 CDS YP_002038417.1 194398348 6478993 complement(1646127..1647488) 1 NC_011072.1 with component II, the glutamine amidotransferase, catalyzes the formation of anthranilate from chorismate and glutamine; anthranilate synthase component I 1647488 trpE 6478993 trpE Streptococcus pneumoniae G54 anthranilate synthase component I YP_002038417.1 1646127 R 512566 CDS YP_002038418.1 194397466 6480409 complement(1648809..1649810) 1 NC_011072.1 identified by match to protein family HMM PF00356; match to protein family HMM PF00532; LacI family transcriptional regulator 1649810 6480409 SPG_1714 Streptococcus pneumoniae G54 LacI family transcriptional regulator YP_002038418.1 1648809 R 512566 CDS YP_002038419.1 194397380 6480195 complement(1650382..1651092) 1 NC_011072.1 identified by match to protein family HMM PF02308; hypothetical protein 1651092 6480195 SPG_1715 Streptococcus pneumoniae G54 hypothetical protein YP_002038419.1 1650382 R 512566 CDS YP_002038420.1 194397545 6479837 complement(1651095..1652786) 1 NC_011072.1 identified by match to protein family HMM PF00528; ABC transporter permease 1652786 6479837 SPG_1716 Streptococcus pneumoniae G54 ABC transporter permease YP_002038420.1 1651095 R 512566 CDS YP_002038421.1 194396924 6479096 complement(1652798..1653808) 1 NC_011072.1 identified by match to protein family HMM PF00005; match to protein family HMM PF03459; match to protein family HMM PF08402; ABC transporter ATP-binding protein 1653808 6479096 SPG_1717 Streptococcus pneumoniae G54 ABC transporter ATP-binding protein YP_002038421.1 1652798 R 512566 CDS YP_002038422.1 194398304 6479872 complement(1653912..1654979) 1 NC_011072.1 ABC transporter substrate-binding protein 1654979 6479872 SPG_1718 Streptococcus pneumoniae G54 ABC transporter substrate-binding protein YP_002038422.1 1653912 R 512566 CDS YP_002038423.1 194397888 6479392 complement(1655004..1655663) 1 NC_011072.1 identified by match to protein family HMM PF08975; hypothetical protein 1655663 6479392 SPG_1719 Streptococcus pneumoniae G54 hypothetical protein YP_002038423.1 1655004 R 512566 CDS YP_002038424.1 194397638 6480816 complement(1656685..1658811) 1 NC_011072.1 identified by glimmer; putative; hypothetical protein 1658811 6480816 SPG_1720 Streptococcus pneumoniae G54 hypothetical protein YP_002038424.1 1656685 R 512566 CDS YP_002038425.1 194397156 6479146 complement(1659974..1661200) 1 NC_011072.1 identified by match to protein family HMM PF01041; capsular polysaccharide biosynthesis protein 1661200 6479146 SPG_1721 Streptococcus pneumoniae G54 capsular polysaccharide biosynthesis protein YP_002038425.1 1659974 R 512566 CDS YP_002038426.1 194396829 6479349 complement(1661243..1661935) 1 NC_011072.1 identified by match to protein family HMM PF02397; glycosyl transferase 1661935 6479349 SPG_1722 Streptococcus pneumoniae G54 glycosyl transferase YP_002038426.1 1661243 R 512566 CDS YP_002038427.1 194398385 6479148 complement(1662108..1663859) 1 NC_011072.1 identified by match to protein family HMM PF00005; match to protein family HMM PF00664; ABC transporter ATP-binding/permease 1663859 6479148 SPG_1723 Streptococcus pneumoniae G54 ABC transporter ATP-binding/permease YP_002038427.1 1662108 R 512566 CDS YP_002038428.1 194398102 6479218 complement(1663849..1665594) 1 NC_011072.1 identified by match to protein family HMM PF00005; match to protein family HMM PF00664; ABC transporter ATP-binding/permease 1665594 6479218 SPG_1724 Streptococcus pneumoniae G54 ABC transporter ATP-binding/permease YP_002038428.1 1663849 R 512566 CDS YP_002038429.1 194397336 6480511 complement(1665800..1666177) 1 NC_011072.1 identified by match to protein family HMM PF04239; hypothetical protein 1666177 6480511 SPG_1725 Streptococcus pneumoniae G54 hypothetical protein YP_002038429.1 1665800 R 512566 CDS YP_002038430.1 194397914 6480542 complement(1666249..1666518) 1 NC_011072.1 hypothetical protein 1666518 6480542 SPG_1726 Streptococcus pneumoniae G54 hypothetical protein YP_002038430.1 1666249 R 512566 CDS YP_002038431.1 194398117 6478874 complement(1666478..1666705) 1 NC_011072.1 hypothetical protein 1666705 6478874 SPG_1727 Streptococcus pneumoniae G54 hypothetical protein YP_002038431.1 1666478 R 512566 CDS YP_002038432.1 194397999 6480240 1666839..1667666 1 NC_011072.1 identified by match to protein family HMM PF03372; match to protein family HMM TIGR00195; match to protein family HMM TIGR00633; exodeoxyribonuclease III 1667666 exoA 6480240 exoA Streptococcus pneumoniae G54 exodeoxyribonuclease III YP_002038432.1 1666839 D 512566 CDS YP_002038433.1 194398609 6479616 1667678..1667821 1 NC_011072.1 hypothetical protein 1667821 6479616 SPG_1729 Streptococcus pneumoniae G54 hypothetical protein YP_002038433.1 1667678 D 512566 CDS YP_002038434.1 194397067 6479195 1667932..1668060 1 NC_011072.1 identified by glimmer; putative; hypothetical protein 1668060 6479195 SPG_1730 Streptococcus pneumoniae G54 hypothetical protein YP_002038434.1 1667932 D 512566 CDS YP_002038435.1 194397591 6480270 1668938..1669519 1 NC_011072.1 Catalyzes the transfer of the phosphoribosyl moiety from 5-phospho--D-ribosyl-1-pyrophosphate (PRib-PP) to the 6-oxo-guanine and -xanthine; xanthine phosphoribosyltransferase 1669519 xpt 6480270 xpt Streptococcus pneumoniae G54 xanthine phosphoribosyltransferase YP_002038435.1 1668938 D 512566 CDS YP_002038436.1 194397687 6479155 1669519..1670781 1 NC_011072.1 identified by match to protein family HMM PF00860; match to protein family HMM PF00916; match to protein family HMM TIGR00801; match to protein family HMM TIGR03173; xanthine permease 1670781 6479155 SPG_1732 Streptococcus pneumoniae G54 xanthine permease YP_002038436.1 1669519 D 512566 CDS YP_002038437.1 194397753 6478882 complement(1670868..1671734) 1 NC_011072.1 Lacks,S.; J. Mol. Biol. 250 (2), 144-155 (1995); identified by match to protein family HMM PF04556; DpnII endonuclease 1671734 dpnB 6478882 dpnB Streptococcus pneumoniae G54 DpnII endonuclease YP_002038437.1 1670868 R 512566 CDS YP_002038438.1 194398425 6480253 complement(1671721..1672491) 1 NC_011072.1 Lacks,S.; J. Mol. Biol. 250 (2), 144-155 (1995); identified by match to protein family HMM PF01555; DNA adenine methyltransferase DpnII 1672491 dpnA 6480253 dpnA Streptococcus pneumoniae G54 DNA adenine methyltransferase DpnII YP_002038438.1 1671721 R 512566 CDS YP_002038439.1 194396739 6480075 complement(1672517..1673371) 1 NC_011072.1 Lacks,S.; J. Mol. Biol. 250 (2), 144-155 (1995); identified by match to protein family HMM PF02086; match to protein family HMM TIGR00571; DNA adenine methyltransferase DpnII 1673371 dpnM 6480075 dpnM Streptococcus pneumoniae G54 DNA adenine methyltransferase DpnII YP_002038439.1 1672517 R 512566 CDS YP_002038440.1 194398029 6480164 complement(1673528..1673932) 1 NC_011072.1 identified by match to protein family HMM PF03061; match to protein family HMM TIGR00369; hypothetical protein 1673932 6480164 SPG_1736 Streptococcus pneumoniae G54 hypothetical protein YP_002038440.1 1673528 R 512566 CDS YP_002038441.1 194397702 6478868 complement(1674002..1675483) 1 NC_011072.1 catalyzes the formation of alpha-D-glucose 1-phosphate and UDP-galactose from UDP-glucose and alpha-D-galactose 1-phosphate in galactose metabolism; galactose-1-phosphate uridylyltransferase 1675483 6478868 SPG_1737 Streptococcus pneumoniae G54 galactose-1-phosphate uridylyltransferase YP_002038441.1 1674002 R 512566 CDS YP_002038442.1 194397014 6480580 complement(1675502..1676680) 1 NC_011072.1 catalyzes the formation of alpha-D-galactose 1-phosphate from D-galactose in galactose metabolism; galactokinase 1676680 6480580 SPG_1738 Streptococcus pneumoniae G54 galactokinase YP_002038442.1 1675502 R 512566 CDS YP_002038443.1 194398429 6480785 1676844..1677851 1 NC_011072.1 identified by match to protein family HMM PF00356; galactose operon repressor 1677851 6480785 SPG_1739 Streptococcus pneumoniae G54 galactose operon repressor YP_002038443.1 1676844 D 512566 CDS YP_002038444.1 194397362 6480250 complement(1677898..1678341) 1 NC_011072.1 contains potential frameshift; alcohol dehydrogenase 1678341 6480250 SPG_1740 Streptococcus pneumoniae G54 alcohol dehydrogenase YP_002038444.1 1677898 R 512566 CDS YP_002038445.1 194398630 6480138 complement(1678338..1678937) 1 NC_011072.1 contains potential frameshift; identified by match to protein family HMM PF08240; alcohol dehydrogenase 1678937 6480138 SPG_1741 Streptococcus pneumoniae G54 alcohol dehydrogenase YP_002038445.1 1678338 R 512566 CDS YP_002038446.1 194398652 6479622 complement(1678938..1679291) 1 NC_011072.1 identified by match to protein family HMM PF00376; MerR family transcriptional regulator 1679291 6479622 SPG_1742 Streptococcus pneumoniae G54 MerR family transcriptional regulator YP_002038446.1 1678938 R 512566 CDS YP_002038447.1 194398216 6478886 complement(1679535..1680425) 1 NC_011072.1 identified by match to protein family HMM PF01545; match to protein family HMM TIGR01297; cation efflux family protein 1680425 6478886 SPG_1743 Streptococcus pneumoniae G54 cation efflux family protein YP_002038447.1 1679535 R 512566 CDS YP_002038448.1 194397111 6478998 1680558..1681094 1 NC_011072.1 identified by match to protein family HMM PF00440; TetR family transcriptional regulator 1681094 6478998 SPG_1744 Streptococcus pneumoniae G54 TetR family transcriptional regulator YP_002038448.1 1680558 D 512566 CDS YP_002038449.1 194398527 6479770 complement(1681260..1682066) 1 NC_011072.1 identified by match to protein family HMM PF04973; match to protein family HMM TIGR01528; nicotinamide mononucleotide transporter PnuC 1682066 6479770 SPG_1745 Streptococcus pneumoniae G54 nicotinamide mononucleotide transporter PnuC YP_002038449.1 1681260 R 512566 CDS YP_002038450.1 194397596 6480662 complement(1682411..1683931) 1 NC_011072.1 identified by match to protein family HMM PF00528; match to protein family HMM PF04069; ABC transporter substrate-binding/permease 1683931 6480662 SPG_1746 Streptococcus pneumoniae G54 ABC transporter substrate-binding/permease YP_002038450.1 1682411 R 512566 CDS YP_002038451.1 194397171 6479222 complement(1683924..1684652) 1 NC_011072.1 identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 1684652 6479222 SPG_1747 Streptococcus pneumoniae G54 ABC transporter ATP-binding protein YP_002038451.1 1683924 R 512566 CDS YP_002038452.1 194397977 6479253 complement(1684667..1685431) 1 NC_011072.1 identified by match to protein family HMM PF07366; hypothetical protein 1685431 6479253 SPG_1748 Streptococcus pneumoniae G54 hypothetical protein YP_002038452.1 1684667 R 512566 CDS YP_002038453.1 194397221 6479060 complement(1685435..1685878) 1 NC_011072.1 identified by match to protein family HMM PF01047; MarR family transcriptional regulator 1685878 6479060 SPG_1749 Streptococcus pneumoniae G54 MarR family transcriptional regulator YP_002038453.1 1685435 R 512566 CDS YP_002038454.1 194398516 6480570 complement(1686560..1686856) 1 NC_011072.1 identified by match to protein family HMM PF08957; hypothetical protein 1686856 6480570 SPG_1750 Streptococcus pneumoniae G54 hypothetical protein YP_002038454.1 1686560 R 512566 CDS YP_002038455.1 194398052 6480388 complement(1686878..1687942) 1 NC_011072.1 identified by match to protein family HMM PF05343; match to protein family HMM TIGR03107; glutamyl aminopeptidase 1687942 6480388 SPG_1751 Streptococcus pneumoniae G54 glutamyl aminopeptidase YP_002038455.1 1686878 R 512566 CDS YP_002038456.1 194398229 6478689 1688062..1688184 1 NC_011072.1 identified by glimmer; putative; hypothetical protein 1688184 6478689 SPG_1752 Streptococcus pneumoniae G54 hypothetical protein YP_002038456.1 1688062 D 512566 CDS YP_002038457.1 194397707 6479140 1688343..1689044 1 NC_011072.1 identified by match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF07993; NAD dependent epimerase/dehydratase family protein 1689044 6479140 SPG_1753 Streptococcus pneumoniae G54 NAD dependent epimerase/dehydratase family protein YP_002038457.1 1688343 D 512566 CDS YP_002038458.1 194397104 6480056 1689467..1690426 1 NC_011072.1 identified by match to protein family HMM PF01032; ABC transporter permease 1690426 6480056 SPG_1754 Streptococcus pneumoniae G54 ABC transporter permease YP_002038458.1 1689467 D 512566 CDS YP_002038459.1 194398271 6480215 1690416..1691372 1 NC_011072.1 identified by match to protein family HMM PF01032; ABC transporter permease 1691372 6480215 SPG_1755 Streptococcus pneumoniae G54 ABC transporter permease YP_002038459.1 1690416 D 512566 CDS YP_002038460.1 194396780 6479011 1691369..1692121 1 NC_011072.1 identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 1692121 6479011 SPG_1756 Streptococcus pneumoniae G54 ABC transporter ATP-binding protein YP_002038460.1 1691369 D 512566 CDS YP_002038461.1 194398454 6479646 1692217..1693182 1 NC_011072.1 identified by match to protein family HMM PF01497; ABC transporter substrate binding protein 1693182 6479646 SPG_1757 Streptococcus pneumoniae G54 ABC transporter substrate binding protein YP_002038461.1 1692217 D 512566 CDS YP_002038462.1 194398569 6480712 complement(1693407..1693649) 1 NC_011072.1 identified by match to protein family HMM PF01809; match to protein family HMM TIGR00278; hypothetical protein 1693649 6480712 SPG_1758 Streptococcus pneumoniae G54 hypothetical protein YP_002038462.1 1693407 R 512566 CDS YP_002038463.1 194398119 6479284 complement(1693649..1694371) 1 NC_011072.1 identified by match to protein family HMM PF00849; match to protein family HMM PF01479; match to protein family HMM TIGR00093; ribosomal large subunit pseudouridine synthase B 1694371 6479284 SPG_1759 Streptococcus pneumoniae G54 ribosomal large subunit pseudouridine synthase B YP_002038463.1 1693649 R 512566 CDS YP_002038464.1 194398542 6480242 complement(1694358..1694927) 1 NC_011072.1 functions during chromosome segregation; may form a condensin-like structure with SMC and ScpA; forms a homodimer; segregation and condensation protein B 1694927 scpB 6480242 scpB Streptococcus pneumoniae G54 segregation and condensation protein B YP_002038464.1 1694358 R 512566 CDS YP_002038465.1 194398080 6480622 complement(1694946..1695674) 1 NC_011072.1 functions during chromosome segregation; may form a condensin-like structure with SMC and ScpB; segregation and condensation protein A 1695674 scpA 6480622 scpA Streptococcus pneumoniae G54 segregation and condensation protein A YP_002038465.1 1694946 R 512566 CDS YP_002038466.1 194397603 6479459 complement(1695674..1696414) 1 NC_011072.1 site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs; site-specific tyrosine recombinase XerD-like protein 1696414 xerD 6479459 xerD Streptococcus pneumoniae G54 site-specific tyrosine recombinase XerD-like protein YP_002038466.1 1695674 R 512566 CDS YP_002038467.1 194397135 6479360 complement(1696405..1696866) 1 NC_011072.1 identified by match to protein family HMM PF00571; hypothetical protein 1696866 6479360 SPG_1763 Streptococcus pneumoniae G54 hypothetical protein YP_002038467.1 1696405 R 512566 CDS YP_002038468.1 194398451 6479745 complement(1696863..1697384) 1 NC_011072.1 identified by match to protein family HMM PF00149; match to protein family HMM TIGR00040; hypothetical protein 1697384 6479745 SPG_1764 Streptococcus pneumoniae G54 hypothetical protein YP_002038468.1 1696863 R 512566 CDS YP_002038469.1 194398619 6480430 complement(1697360..1698331) 1 NC_011072.1 HAM1-like protein; Rec-dependent growth; RgdB; yggV; it is suspected that this protein functions to remove misincorporated bases such as xanthine or hypoxanthine; putative fused deoxyribonucleotide triphosphate pyrophosphatase/unknown domain protein 1698331 6480430 SPG_1765 Streptococcus pneumoniae G54 putative fused deoxyribonucleotide triphosphate pyrophosphatase/unknown domain protein YP_002038469.1 1697360 R 512566 CDS YP_002038470.1 194397943 6479463 complement(1698328..1699122) 1 NC_011072.1 converts L-glutamate to D-glutamate, a component of peptidoglycan; glutamate racemase 1699122 murI 6479463 murI Streptococcus pneumoniae G54 glutamate racemase YP_002038470.1 1698328 R 512566 CDS YP_002038471.1 194398343 6479074 complement(1699329..1699577) 1 NC_011072.1 hypothetical protein 1699577 6479074 SPG_1767 Streptococcus pneumoniae G54 hypothetical protein YP_002038471.1 1699329 R 512566 CDS YP_002038472.1 194397841 6480257 complement(1699833..1701458) 1 NC_011072.1 identified by match to protein family HMM PF00128; match to protein family HMM TIGR02403; alpha,alpha-phosphotrehalase 1701458 treC 6480257 treC Streptococcus pneumoniae G54 alpha,alpha-phosphotrehalase YP_002038472.1 1699833 R 512566 CDS YP_002038473.1 194398340 6480117 complement(1701636..1703603) 1 NC_011072.1 identified by match to protein family HMM PF00358; match to protein family HMM PF00367; match to protein family HMM PF02378; match to protein family HMM TIGR00826; match to protein family HMM TIGR00830; match to protein family HMM TIGR01992; PTS system transporter subunit IIBCA 1703603 6480117 SPG_1769 Streptococcus pneumoniae G54 PTS system transporter subunit IIBCA YP_002038473.1 1701636 R 512566 CDS YP_002038474.1 194397174 6480782 1703788..1704498 1 NC_011072.1 identified by match to protein family HMM PF00392; match to protein family HMM PF07702; match to protein family HMM TIGR02404; transcriptional repressor 1704498 6480782 SPG_1770 Streptococcus pneumoniae G54 transcriptional repressor YP_002038474.1 1703788 D 512566 CDS YP_002038475.1 194397496 6479385 1704653..1704889 1 NC_011072.1 IS1167 transposase 1704889 6479385 SPG_1771 Streptococcus pneumoniae G54 IS1167 transposase YP_002038475.1 1704653 D 512566 CDS YP_002038476.1 194398113 6479452 1704914..1705171 1 NC_011072.1 IS1167 transposase 1705171 6479452 SPG_1772 Streptococcus pneumoniae G54 IS1167 transposase YP_002038476.1 1704914 D 512566 CDS YP_002038477.1 194397903 6480483 1705452..1705979 1 NC_011072.1 IS1167 transposase 1705979 6480483 SPG_1773 Streptococcus pneumoniae G54 IS1167 transposase YP_002038477.1 1705452 D 512566 CDS YP_002038478.1 194398483 6479511 complement(1706054..1706980) 1 NC_011072.1 identified by match to protein family HMM PF00005; match to protein family HMM PF08352; ABC transporter ATP-binding protein 1706980 6479511 SPG_1774 Streptococcus pneumoniae G54 ABC transporter ATP-binding protein YP_002038478.1 1706054 R 512566 CDS YP_002038479.1 194396908 6479940 complement(1706991..1708058) 1 NC_011072.1 identified by match to protein family HMM PF00005; match to protein family HMM PF08352; match to protein family HMM TIGR01727; ABC transporter ATP-binding protein 1708058 6479940 SPG_1775 Streptococcus pneumoniae G54 ABC transporter ATP-binding protein YP_002038479.1 1706991 R 512566 CDS YP_002038480.1 194397506 6480047 complement(1708067..1708993) 1 NC_011072.1 identified by match to protein family HMM PF00528; ABC transporter permease 1708993 6480047 SPG_1776 Streptococcus pneumoniae G54 ABC transporter permease YP_002038480.1 1708067 R 512566 CDS YP_002038481.1 194396985 6479004 complement(1708993..1710489) 1 NC_011072.1 identified by match to protein family HMM PF00528; ABC transporter permease 1710489 6479004 SPG_1777 Streptococcus pneumoniae G54 ABC transporter permease YP_002038481.1 1708993 R 512566 CDS YP_002038482.1 194398599 6479981 complement(1710556..1712535) 1 NC_011072.1 identified by match to protein family HMM PF00496; ABC transporter substrate binding protein 1712535 6479981 SPG_1778 Streptococcus pneumoniae G54 ABC transporter substrate binding protein YP_002038482.1 1710556 R 512566 CDS YP_002038483.1 194398228 6479609 1713014..1714360 1 NC_011072.1 identified by match to protein family HMM PF01609; IS1380-Spn1 transposase 1714360 6479609 SPG_1779 Streptococcus pneumoniae G54 IS1380-Spn1 transposase YP_002038483.1 1713014 D 512566 CDS YP_002038484.1 194398678 6478770 complement(1714930..1716123) 1 NC_011072.1 identified by glimmer; putative; hypothetical protein 1716123 6478770 SPG_1780 Streptococcus pneumoniae G54 hypothetical protein YP_002038484.1 1714930 R 512566 CDS YP_002038485.1 194398242 6479301 complement(1716261..1717703) 1 NC_011072.1 identified by match to protein family HMM PF00128; sucrose phosphorylase 1717703 6479301 SPG_1781 Streptococcus pneumoniae G54 sucrose phosphorylase YP_002038485.1 1716261 R 512566 CDS YP_002038486.1 194396738 6479216 complement(1718061..1718894) 1 NC_011072.1 identified by match to protein family HMM PF00528; sugar ABC transporter permease 1718894 6479216 SPG_1782 Streptococcus pneumoniae G54 sugar ABC transporter permease YP_002038486.1 1718061 R 512566 CDS YP_002038487.1 194398428 6480077 complement(1718908..1719774) 1 NC_011072.1 identified by match to protein family HMM PF00528; ABC transporter ATP-binding/permease 1719774 6480077 SPG_1783 Streptococcus pneumoniae G54 ABC transporter ATP-binding/permease YP_002038487.1 1718908 R 512566 CDS YP_002038488.1 194398544 6480249 complement(1719788..1721047) 1 NC_011072.1 identified by match to protein family HMM PF01547; ABC transporter sugar-binding protein 1721047 6480249 SPG_1784 Streptococcus pneumoniae G54 ABC transporter sugar-binding protein YP_002038488.1 1719788 R 512566 CDS YP_002038489.1 194397358 6480104 complement(1721139..1723301) 1 NC_011072.1 identified by match to protein family HMM PF02065; alpha-galactosidase AgaN 1723301 6480104 SPG_1785 Streptococcus pneumoniae G54 alpha-galactosidase AgaN YP_002038489.1 1721139 R 512566 CDS YP_002038490.1 194397843 6480692 1723409..1724269 1 NC_011072.1 identified by match to protein family HMM PF00165; match to protein family HMM PF02311; msm operon regulatory protein 1724269 msmR 6480692 msmR Streptococcus pneumoniae G54 msm operon regulatory protein YP_002038490.1 1723409 D 512566 CDS YP_002038491.1 194397300 6480295 1724266..1725201 1 NC_011072.1 catalyzes the formation of biotinyl-5'-AMP, also acts as a transcriptional repressor of the biotin operon; biotin--protein ligase 1725201 birA 6480295 birA Streptococcus pneumoniae G54 biotin--protein ligase YP_002038491.1 1724266 D 512566 CDS YP_002038492.1 194398750 6480454 complement(1732106..1733461) 1 NC_011072.1 contains potential frameshift; identified by match to protein family HMM PF05958; match to protein family HMM TIGR00479; 23S rRNA (uracil-5-)-methyltransferase RumA 1733461 6480454 SPG_1810 Streptococcus pneumoniae G54 23S rRNA (uracil-5-)-methyltransferase RumA YP_002038492.1 1732106 R 512566 CDS YP_002038493.1 194396749 6478765 1733499..1734275 1 NC_011072.1 binds RecA and inhibits RecA-mediated DNA strand exchange and ATP hydrolysis and coprotease activities; recombination regulator RecX 1734275 recX 6478765 recX Streptococcus pneumoniae G54 recombination regulator RecX YP_002038493.1 1733499 D 512566 CDS YP_002038494.1 194397455 6479825 1734364..1734897 1 NC_011072.1 identified by match to protein family HMM PF04167; hypothetical protein 1734897 6479825 SPG_1812 Streptococcus pneumoniae G54 hypothetical protein YP_002038494.1 1734364 D 512566 CDS YP_002038495.1 194398209 6480470 complement(1735253..1735459) 1 NC_011072.1 hypothetical protein 1735459 6480470 SPG_1813 Streptococcus pneumoniae G54 hypothetical protein YP_002038495.1 1735253 R 512566 CDS YP_002038496.1 194397950 6478775 complement(1735771..1736109) 1 NC_011072.1 identified by match to protein family HMM PF01381; transcriptional regulator 1736109 6478775 SPG_1814 Streptococcus pneumoniae G54 transcriptional regulator YP_002038496.1 1735771 R 512566 CDS YP_002038497.1 194398436 6479497 complement(1736122..1736895) 1 NC_011072.1 identified by match to protein family HMM PF08241; match to protein family HMM PF08242; hypothetical protein 1736895 6479497 SPG_1815 Streptococcus pneumoniae G54 hypothetical protein YP_002038497.1 1736122 R 512566 CDS YP_002038498.1 194397182 6480587 complement(1737422..1737673) 1 NC_011072.1 hypothetical protein 1737673 6480587 SPG_1816 Streptococcus pneumoniae G54 hypothetical protein YP_002038498.1 1737422 R 512566 CDS YP_002038499.1 194398687 6479251 complement(1737767..1737976) 1 NC_011072.1 hypothetical protein 1737976 6479251 SPG_1817 Streptococcus pneumoniae G54 hypothetical protein YP_002038499.1 1737767 R 512566 CDS YP_002038500.1 194398217 6478879 complement(1738234..1739856) 1 NC_011072.1 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth; chaperonin GroEL 1739856 groEL 6478879 groEL Streptococcus pneumoniae G54 chaperonin GroEL YP_002038500.1 1738234 R 512566 CDS YP_002038501.1 194397194 6479520 complement(1739872..1740156) 1 NC_011072.1 10 kDa chaperonin; Cpn10; GroES; forms homoheptameric ring; binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it; folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES; release of the folded substrate is dependent on ATP binding and hydrolysis in the trans ring; co-chaperonin GroES 1740156 groES 6479520 groES Streptococcus pneumoniae G54 co-chaperonin GroES YP_002038501.1 1739872 R 512566 CDS YP_002038502.1 194396702 6480496 complement(1740426..1740821) 1 NC_011072.1 binds to single stranded DNA and may facilitate the binding and interaction of other proteins to DNA; single-stranded DNA-binding protein 1740821 ssb 6480496 ssb Streptococcus pneumoniae G54 single-stranded DNA-binding protein YP_002038502.1 1740426 R 512566 CDS YP_002038503.1 194398401 6479737 complement(1740899..1741660) 1 NC_011072.1 identified by match to protein family HMM PF00106; short chain dehydrogenase/reductase family oxidoreductase 1741660 6479737 SPG_1821 Streptococcus pneumoniae G54 short chain dehydrogenase/reductase family oxidoreductase YP_002038503.1 1740899 R 512566 CDS YP_002038504.1 194397919 6479172 complement(1741693..1742319) 1 NC_011072.1 identified by match to protein family HMM PF01588; hypothetical protein 1742319 6479172 SPG_1822 Streptococcus pneumoniae G54 hypothetical protein YP_002038504.1 1741693 R 512566 CDS YP_002038505.1 194396919 6479176 complement(1742335..1742652) 1 NC_011072.1 identified by match to protein family HMM PF00085; thioredoxin family protein 1742652 6479176 SPG_1823 Streptococcus pneumoniae G54 thioredoxin family protein YP_002038505.1 1742335 R 512566 CDS YP_002038506.1 194398704 6480150 complement(1742649..1742939) 1 NC_011072.1 hypothetical protein 1742939 6480150 SPG_1824 Streptococcus pneumoniae G54 hypothetical protein YP_002038506.1 1742649 R 512566 CDS YP_002038507.1 194398178 6479443 complement(1743233..1743376) 1 NC_011072.1 identified by match to protein family HMM PF01473; hypothetical protein 1743376 6479443 SPG_1825 Streptococcus pneumoniae G54 hypothetical protein YP_002038507.1 1743233 R 512566 CDS YP_002038508.1 194397783 6480518 complement(1743585..1744259) 1 NC_011072.1 hypothetical protein 1744259 6480518 SPG_1826 Streptococcus pneumoniae G54 hypothetical protein YP_002038508.1 1743585 R 512566 CDS YP_002038509.1 194397236 6480696 complement(1744265..1744711) 1 NC_011072.1 identified by match to protein family HMM PF04397; LytTr DNA-binding domain-containing protein 1744711 6480696 SPG_1827 Streptococcus pneumoniae G54 LytTr DNA-binding domain-containing protein YP_002038509.1 1744265 R 512566 CDS YP_002038510.1 194397121 6480170 complement(1744825..1745328) 1 NC_011072.1 identified by match to protein family HMM PF01569; hypothetical protein 1745328 6480170 SPG_1828 Streptococcus pneumoniae G54 hypothetical protein YP_002038510.1 1744825 R 512566 CDS YP_002038511.1 194397107 6479702 complement(1745325..1745687) 1 NC_011072.1 hypothetical protein 1745687 6479702 SPG_1829 Streptococcus pneumoniae G54 hypothetical protein YP_002038511.1 1745325 R 512566 CDS YP_002038512.1 194397740 6479983 complement(1745753..1746784) 1 NC_011072.1 identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 1746784 6479983 SPG_1830 Streptococcus pneumoniae G54 ABC transporter ATP-binding protein YP_002038512.1 1745753 R 512566 CDS YP_002038513.1 194397271 6480383 complement(1746791..1747168) 1 NC_011072.1 ABC transporter permease 1747168 6480383 SPG_1831 Streptococcus pneumoniae G54 ABC transporter permease YP_002038513.1 1746791 R 512566 CDS YP_002038514.1 194396895 6478766 complement(1747184..1747612) 1 NC_011072.1 ABC transporter permease 1747612 6478766 SPG_1832 Streptococcus pneumoniae G54 ABC transporter permease YP_002038514.1 1747184 R 512566 CDS YP_002038515.1 194396857 6479110 complement(1747651..1747950) 1 NC_011072.1 transcriptional regulator 1747950 6479110 SPG_1833 Streptococcus pneumoniae G54 transcriptional regulator YP_002038515.1 1747651 R 512566 CDS YP_002038516.1 194398574 6479342 complement(1747963..1748100) 1 NC_011072.1 transcriptional regulator 1748100 6479342 SPG_1834 Streptococcus pneumoniae G54 transcriptional regulator YP_002038516.1 1747963 R 512566 CDS YP_002038517.1 194398105 6478983 complement(1748224..1748940) 1 NC_011072.1 identified by match to protein family HMM PF01709; match to protein family HMM TIGR01033; hypothetical protein 1748940 6478983 SPG_1835 Streptococcus pneumoniae G54 hypothetical protein YP_002038517.1 1748224 R 512566 CDS YP_002038518.1 194397945 6479683 complement(1749821..1751236) 1 NC_011072.1 identified by match to protein family HMM PF01289; pneumolysin 1751236 ply 6479683 ply Streptococcus pneumoniae G54 pneumolysin YP_002038518.1 1749821 R 512566 CDS YP_002038519.1 194397263 6479076 complement(1751247..1751579) 1 NC_011072.1 hypothetical protein 1751579 6479076 SPG_1837 Streptococcus pneumoniae G54 hypothetical protein YP_002038519.1 1751247 R 512566 CDS YP_002038520.1 194397891 6479124 complement(1751650..1752258) 1 NC_011072.1 hypothetical protein 1752258 6479124 SPG_1838 Streptococcus pneumoniae G54 hypothetical protein YP_002038520.1 1751650 R 512566 CDS YP_002038521.1 194397032 6478907 complement(1752271..1752729) 1 NC_011072.1 hypothetical protein 1752729 6478907 SPG_1839 Streptococcus pneumoniae G54 hypothetical protein YP_002038521.1 1752271 R 512566 CDS YP_002038522.1 194397512 6479854 1752854..1753657 1 NC_011072.1 identified by match to protein family HMM PF01609; transposase 1753657 6479854 SPG_1840 Streptococcus pneumoniae G54 transposase YP_002038522.1 1752854 D 512566 CDS YP_002038523.1 194397610 6479378 complement(1754395..1754655) 1 NC_011072.1 hypothetical protein 1754655 6479378 SPG_1841 Streptococcus pneumoniae G54 hypothetical protein YP_002038523.1 1754395 R 512566 CDS YP_002038524.1 194398061 6479044 complement(1754714..1755265) 1 NC_011072.1 hypothetical protein 1755265 6479044 SPG_1842 Streptococcus pneumoniae G54 hypothetical protein YP_002038524.1 1754714 R 512566 CDS YP_002038525.1 194398382 6479037 complement(1755255..1756250) 1 NC_011072.1 hypothetical protein 1756250 6479037 SPG_1843 Streptococcus pneumoniae G54 hypothetical protein YP_002038525.1 1755255 R 512566 CDS YP_002038526.1 194396682 6479308 complement(1756658..1757083) 1 NC_011072.1 hypothetical protein 1757083 6479308 SPG_1844 Streptococcus pneumoniae G54 hypothetical protein YP_002038526.1 1756658 R 512566 CDS YP_002038527.1 194396825 6479727 complement(1757212..1757571) 1 NC_011072.1 hypothetical protein 1757571 6479727 SPG_1845 Streptococcus pneumoniae G54 hypothetical protein YP_002038527.1 1757212 R 512566 CDS YP_002038528.1 194397882 6478748 complement(1757810..1757971) 1 NC_011072.1 type II restriction-modification system regulatory protein 1757971 6478748 SPG_1846 Streptococcus pneumoniae G54 type II restriction-modification system regulatory protein YP_002038528.1 1757810 R 512566 CDS YP_002038529.1 194397555 6480363 complement(1758317..1759273) 1 NC_011072.1 identified by match to protein family HMM PF01473; match to protein family HMM PF01510; autolysin 1759273 lytA 6480363 lytA Streptococcus pneumoniae G54 autolysin YP_002038529.1 1758317 R 512566 CDS YP_002038530.1 194396964 6479472 complement(1759649..1761019) 1 NC_011072.1 identified by match to protein family HMM PF01554; match to protein family HMM TIGR00797; MATE efflux family protein 1761019 6479472 SPG_1848 Streptococcus pneumoniae G54 MATE efflux family protein YP_002038530.1 1759649 R 512566 CDS YP_002038531.1 194398747 6480620 complement(1761326..1762492) 1 NC_011072.1 catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs; recombinase A 1762492 recA 6480620 recA Streptococcus pneumoniae G54 recombinase A YP_002038531.1 1761326 R 512566 CDS YP_002038532.1 194398434 6478649 complement(1762547..1763803) 1 NC_011072.1 identified by match to protein family HMM PF00994; match to protein family HMM PF02464; match to protein family HMM TIGR00199; match to protein family HMM TIGR00200; competence damage-inducible protein A 1763803 6478649 SPG_1850 Streptococcus pneumoniae G54 competence damage-inducible protein A YP_002038532.1 1762547 R 512566 CDS YP_002038533.1 194397669 6480265 complement(1763888..1764904) 1 NC_011072.1 identified by match to protein family HMM PF03816; match to protein family HMM TIGR00350; transcriptional regulator 1764904 6480265 SPG_1851 Streptococcus pneumoniae G54 transcriptional regulator YP_002038533.1 1763888 R 512566 CDS YP_002038534.1 194397197 6479568 complement(1764912..1765430) 1 NC_011072.1 identified by match to protein family HMM PF00583; GNAT family acetyltransferase 1765430 6479568 SPG_1852 Streptococcus pneumoniae G54 GNAT family acetyltransferase YP_002038534.1 1764912 R 512566 CDS YP_002038535.1 194396875 6479773 complement(1765420..1765863) 1 NC_011072.1 identified by match to protein family HMM PF02367; match to protein family HMM TIGR00150; hypothetical protein 1765863 6479773 SPG_1853 Streptococcus pneumoniae G54 hypothetical protein YP_002038535.1 1765420 R 512566 CDS YP_002038536.1 194398124 6478727 complement(1765949..1766569) 1 NC_011072.1 identified by glimmer; putative; hypothetical protein 1766569 6478727 SPG_1854 Streptococcus pneumoniae G54 hypothetical protein YP_002038536.1 1765949 R 512566 CDS YP_002038537.1 194397893 6480394 complement(1766952..1767815) 1 NC_011072.1 identified by match to protein family HMM PF01381; transcriptional activator 1767815 6480394 SPG_1855 Streptococcus pneumoniae G54 transcriptional activator YP_002038537.1 1766952 R 512566 CDS YP_002038538.1 194397896 6478909 1768487..1768783 1 NC_011072.1 identified by glimmer; putative; hypothetical protein 1768783 6478909 SPG_1856 Streptococcus pneumoniae G54 hypothetical protein YP_002038538.1 1768487 D 512566 CDS YP_002038539.1 194397808 6479510 1768886..1770901 1 NC_011072.1 identified by match to protein family HMM PF07242; match to protein family HMM TIGR01654; hypothetical protein 1770901 6479510 SPG_1857 Streptococcus pneumoniae G54 hypothetical protein YP_002038539.1 1768886 D 512566 CDS YP_002038540.1 194398263 6480666 1770903..1771535 1 NC_011072.1 identified by match to protein family HMM PF00005; match to protein family HMM TIGR03608; ABC transporter ATP-binding protein 1771535 6480666 SPG_1858 Streptococcus pneumoniae G54 ABC transporter ATP-binding protein YP_002038540.1 1770903 D 512566 CDS YP_002038541.1 194396910 6479419 1771676..1771954 1 NC_011072.1 hypothetical protein 1771954 6479419 SPG_1859 Streptococcus pneumoniae G54 hypothetical protein YP_002038541.1 1771676 D 512566 CDS YP_002038542.1 194397364 6479809 complement(1772464..1772877) 1 NC_011072.1 catalyzes the formation of nucleoside triphosphate from ATP and nucleoside diphosphate; nucleoside diphosphate kinase 1772877 ndk 6479809 ndk Streptococcus pneumoniae G54 nucleoside diphosphate kinase YP_002038542.1 1772464 R 512566 CDS YP_002038543.1 194398481 6480071 complement(1772988..1776665) 1 NC_011072.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Subunit beta' binds to sigma factor allowing it to bind to the -10 region of the promoter; DNA-directed RNA polymerase subunit beta' 1776665 rpoC 6480071 rpoC Streptococcus pneumoniae G54 DNA-directed RNA polymerase subunit beta' YP_002038543.1 1772988 R 512566 CDS YP_002038544.1 194396940 6479938 complement(1776698..1780309) 1 NC_011072.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme; DNA-directed RNA polymerase subunit beta 1780309 rpoB 6479938 rpoB Streptococcus pneumoniae G54 DNA-directed RNA polymerase subunit beta YP_002038544.1 1776698 R 512566 CDS YP_002038545.1 194397580 6479583 complement(1780993..1782324) 1 NC_011072.1 identified by match to protein family HMM PF00571; match to protein family HMM PF01595; match to protein family HMM PF03471; CBS domain membrane protein 1782324 6479583 SPG_1864 Streptococcus pneumoniae G54 CBS domain membrane protein YP_002038545.1 1780993 R 512566 CDS YP_002038546.1 194398176 6479370 complement(1782615..1783439) 1 NC_011072.1 identified by match to protein family HMM PF01223; DNA-entry nuclease 1783439 6479370 SPG_1865 Streptococcus pneumoniae G54 DNA-entry nuclease YP_002038546.1 1782615 R 512566 CDS YP_002038547.1 194398039 6480033 complement(1783478..1783666) 1 NC_011072.1 hypothetical protein 1783666 6480033 SPG_1866 Streptococcus pneumoniae G54 hypothetical protein YP_002038547.1 1783478 R 512566 CDS YP_002038548.1 194398632 6479489 complement(1783659..1784942) 1 NC_011072.1 adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active; UDP-N-acetylglucosamine 1-carboxyvinyltransferase 1784942 murA2 6479489 murA2 Streptococcus pneumoniae G54 UDP-N-acetylglucosamine 1-carboxyvinyltransferase YP_002038548.1 1783659 R 512566 CDS YP_002038549.1 194396948 6478945 complement(1784966..1785196) 1 NC_011072.1 identified by glimmer; putative; hypothetical protein 1785196 6478945 SPG_1868 Streptococcus pneumoniae G54 hypothetical protein YP_002038549.1 1784966 R 512566 CDS YP_002038550.1 194397423 6479670 complement(1785254..1786291) 1 NC_011072.1 hypothetical protein 1786291 6479670 SPG_1869 Streptococcus pneumoniae G54 hypothetical protein YP_002038550.1 1785254 R 512566 CDS YP_002038551.1 194397906 6479937 complement(1786275..1786763) 1 NC_011072.1 Catalyzes the conversion of ATP and pantetheine 4'-phosphate to diphosphate and 3'-dephospho-coA; phosphopantetheine adenylyltransferase 1786763 coaD 6479937 coaD Streptococcus pneumoniae G54 phosphopantetheine adenylyltransferase YP_002038551.1 1786275 R 512566 CDS YP_002038552.1 194398376 6478895 complement(1786753..1787292) 1 NC_011072.1 identified by match to protein family HMM PF03602; match to protein family HMM TIGR00095; type II DNA modification methyltransferase 1787292 6478895 SPG_1871 Streptococcus pneumoniae G54 type II DNA modification methyltransferase YP_002038552.1 1786753 R 512566 CDS YP_002038553.1 194396704 6478674 complement(1787357..1788349) 1 NC_011072.1 catalyzes the formation of asparagine from aspartate and ammonia; asparagine synthetase AsnA 1788349 asnA 6478674 asnA Streptococcus pneumoniae G54 asparagine synthetase AsnA YP_002038553.1 1787357 R 512566 CDS YP_002038554.1 194398187 6479891 complement(1788462..1789145) 1 NC_011072.1 identified by match to protein family HMM PF01027; hypothetical protein 1789145 6479891 SPG_1873 Streptococcus pneumoniae G54 hypothetical protein YP_002038554.1 1788462 R 512566 CDS YP_002038555.1 194397115 6480342 complement(1789201..1789461) 1 NC_011072.1 contains potential frameshift; identified by match to protein family HMM PF00588; rRNA/tRNA methylase 1789461 6480342 SPG_1874 Streptococcus pneumoniae G54 rRNA/tRNA methylase YP_002038555.1 1789201 R 512566 CDS YP_002038556.1 194398548 6480191 complement(1789548..1789940) 1 NC_011072.1 contains potential frameshift; identified by match to protein family HMM PF08032; rRNA/tRNA methylase 1789940 6480191 SPG_1875 Streptococcus pneumoniae G54 rRNA/tRNA methylase YP_002038556.1 1789548 R 512566 CDS YP_002038557.1 194398049 6480674 1789974..1790252 1 NC_011072.1 catalyzes the hydrolysis of acylphosphate; acylphosphatase 1790252 6480674 SPG_1876 Streptococcus pneumoniae G54 acylphosphatase YP_002038557.1 1789974 D 512566 CDS YP_002038558.1 194397013 6479111 1790330..1791256 1 NC_011072.1 involved in biogenesis of membrane proteins; Firmicutes specific proteins are shorter than other bacterial counterparts and have a signal peptide and lipid attachment site; OxaA-like protein precursor 1791256 6479111 SPG_1877 Streptococcus pneumoniae G54 OxaA-like protein precursor YP_002038558.1 1790330 D 512566 CDS YP_002038559.1 194397459 6480151 complement(1791331..1792125) 1 NC_011072.1 identified by match to protein family HMM PF04055; match to protein family HMM TIGR02493; pyruvate formate-lyase 1-activating enzyme 1792125 pflA 6480151 pflA Streptococcus pneumoniae G54 pyruvate formate-lyase 1-activating enzyme YP_002038559.1 1791331 R 512566 CDS YP_002038560.1 194396976 6479815 complement(1792251..1793501) 1 NC_011072.1 identified by match to protein family HMM PF00278; match to protein family HMM PF02784; diaminopimelate decarboxylase 1793501 lysA 6479815 lysA Streptococcus pneumoniae G54 diaminopimelate decarboxylase YP_002038560.1 1792251 R 512566 CDS YP_002038561.1 194398699 6479954 complement(1793568..1794395) 1 NC_011072.1 identified by match to protein family HMM PF00156; match to protein family HMM PF09182; match to protein family HMM TIGR01743; pur operon repressor 1794395 purR 6479954 purR Streptococcus pneumoniae G54 pur operon repressor YP_002038561.1 1793568 R 512566 CDS YP_002038562.1 194398230 6479106 complement(1794662..1795603) 1 NC_011072.1 identified by match to protein family HMM PF01336; cmp-binding-factor 1 1795603 6479106 SPG_1881 Streptococcus pneumoniae G54 cmp-binding-factor 1 YP_002038562.1 1794662 R 512566 CDS YP_002038563.1 194397209 6479141 complement(1795593..1796849) 1 NC_011072.1 identified by match to protein family HMM PF02646; hypothetical protein 1796849 6479141 SPG_1882 Streptococcus pneumoniae G54 hypothetical protein YP_002038563.1 1795593 R 512566 CDS YP_002038564.1 194396748 6480577 complement(1796851..1797513) 1 NC_011072.1 identified by match to protein family HMM PF04263; match to protein family HMM PF04265; match to protein family HMM TIGR01378; Thiamine pyrophosphokinase 1797513 6480577 SPG_1883 Streptococcus pneumoniae G54 Thiamine pyrophosphokinase YP_002038564.1 1796851 R 512566 CDS YP_002038565.1 194396968 6479704 complement(1797476..1798132) 1 NC_011072.1 identified by match to protein family HMM PF00834; match to protein family HMM TIGR01163; ribulose-phosphate 3-epimerase 1798132 rpe 6479704 rpe Streptococcus pneumoniae G54 ribulose-phosphate 3-epimerase YP_002038565.1 1797476 R 512566 CDS YP_002038566.1 194397972 6479993 complement(1798143..1799021) 1 NC_011072.1 EngC; RsgA; CpgA; circularly permuted GTPase; ribosome small subunit-dependent GTPase A; has the pattern G4-G1-G3 as opposed to other GTPases; interacts strongly with 30S ribosome which stimulates GTPase activity; ribosome-associated GTPase 1799021 6479993 SPG_1885 Streptococcus pneumoniae G54 ribosome-associated GTPase YP_002038566.1 1798143 R 512566 CDS YP_002038567.1 194397125 6478731 complement(1799023..1799895) 1 NC_011072.1 catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin; dimethyladenosine transferase 1799895 ksgA 6478731 ksgA Streptococcus pneumoniae G54 dimethyladenosine transferase YP_002038567.1 1799023 R 512566 CDS YP_002038568.1 194397594 6480119 complement(1800026..1800334) 1 NC_011072.1 hypothetical protein 1800334 6480119 SPG_1887 Streptococcus pneumoniae G54 hypothetical protein YP_002038568.1 1800026 R 512566 CDS YP_002038569.1 194398352 6478706 complement(1800327..1800968) 1 NC_011072.1 identified by match to protein family HMM PF00005; match to protein family HMM TIGR03608; ABC transporter ATP-binding protein 1800968 6478706 SPG_1888 Streptococcus pneumoniae G54 ABC transporter ATP-binding protein YP_002038569.1 1800327 R 512566 CDS YP_002038570.1 194396666 6479904 complement(1800970..1803000) 1 NC_011072.1 identified by match to protein family HMM PF07242; match to protein family HMM TIGR01654; bacteriocin-associated integral membrane protein 1803000 6479904 SPG_1889 Streptococcus pneumoniae G54 bacteriocin-associated integral membrane protein YP_002038570.1 1800970 R 512566 CDS YP_002038571.1 194396901 6479769 complement(1803077..1803373) 1 NC_011072.1 identified by glimmer; putative; hypothetical protein 1803373 6479769 SPG_1890 Streptococcus pneumoniae G54 hypothetical protein YP_002038571.1 1803077 R 512566 CDS YP_002038572.1 194397378 6478860 complement(1803693..1804592) 1 NC_011072.1 transcriptional regulator PlcR 1804592 6478860 SPG_1891 Streptococcus pneumoniae G54 transcriptional regulator PlcR YP_002038572.1 1803693 R 512566 CDS YP_002038573.1 194398056 6479807 complement(1804664..1805224) 1 NC_011072.1 identified by match to protein family HMM PF01751; match to protein family HMM TIGR00334; primase-like protein 1805224 6479807 SPG_1892 Streptococcus pneumoniae G54 primase-like protein YP_002038573.1 1804664 R 512566 CDS YP_002038574.1 194398517 6478665 complement(1805224..1805997) 1 NC_011072.1 identified by match to protein family HMM PF01026; match to protein family HMM TIGR00010; TatD family hydrolase 1805997 6478665 SPG_1893 Streptococcus pneumoniae G54 TatD family hydrolase YP_002038574.1 1805224 R 512566 CDS YP_002038575.1 194397795 6480793 complement(1806293..1806967) 1 NC_011072.1 identified by match to protein family HMM PF00746; match to protein family HMM TIGR01167; LPXTG-motif cell wall anchor domain 1806967 6480793 SPG_1894 Streptococcus pneumoniae G54 LPXTG-motif cell wall anchor domain YP_002038575.1 1806293 R 512566 CDS YP_002038576.1 194398497 6480723 complement(1807230..1807364) 1 NC_011072.1 in Escherichia coli transcription of this gene is enhanced by polyamines; 50S ribosomal protein L34 1807364 rpmH 6480723 rpmH Streptococcus pneumoniae G54 50S ribosomal protein L34 YP_002038576.1 1807230 R 512566 CDS YP_002038577.1 194396664 6480764 complement(1807509..1808723) 1 NC_011072.1 broad specificity; family IV; in Corynebacterium glutamicum this protein can use glutamate, 2-aminobutyrate, and aspartate as amino donors and pyruvate as the acceptor; aminotransferase AlaT 1808723 6480764 SPG_1896 Streptococcus pneumoniae G54 aminotransferase AlaT YP_002038577.1 1807509 R 512566 CDS YP_002038578.1 194397557 6479846 complement(1808879..1809172) 1 NC_011072.1 hypothetical protein 1809172 6479846 SPG_1897 Streptococcus pneumoniae G54 hypothetical protein YP_002038578.1 1808879 R 512566 CDS YP_002038579.1 194397368 6478799 1809335..1809787 1 NC_011072.1 identified by match to protein family HMM PF00582; hypothetical protein 1809787 6478799 SPG_1898 Streptococcus pneumoniae G54 hypothetical protein YP_002038579.1 1809335 D 512566 CDS YP_002038580.1 194398524 6480012 complement(1809822..1811210) 1 NC_011072.1 identified by match to protein family HMM PF00702; match to protein family HMM PF05116; match to protein family HMM PF08282; match to protein family HMM TIGR00099; match to protein family HMM TIGR01484; hypothetical protein 1811210 6480012 SPG_1899 Streptococcus pneumoniae G54 hypothetical protein YP_002038580.1 1809822 R 512566 CDS YP_002038581.1 194398308 6480147 1811276..1812238 1 NC_011072.1 identified by match to protein family HMM PF00710; L-asparaginase 1812238 6480147 SPG_1900 Streptococcus pneumoniae G54 L-asparaginase YP_002038581.1 1811276 D 512566 CDS YP_002038582.1 194396759 6479165 complement(1812444..1813454) 1 NC_011072.1 identified by match to protein family HMM PF00356; match to protein family HMM PF00532; match to protein family HMM TIGR01481; catabolite control protein CcpA 1813454 6479165 SPG_1901 Streptococcus pneumoniae G54 catabolite control protein CcpA YP_002038582.1 1812444 R 512566 CDS YP_002038583.1 194398168 6480145 complement(1813879..1814478) 1 NC_011072.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00196; response regulator 1814478 6480145 SPG_1902 Streptococcus pneumoniae G54 response regulator YP_002038583.1 1813879 R 512566 CDS YP_002038584.1 194398741 6480376 complement(1814480..1815577) 1 NC_011072.1 identified by match to protein family HMM PF02518; match to protein family HMM PF07730; histidine kinase 1815577 6480376 SPG_1903 Streptococcus pneumoniae G54 histidine kinase YP_002038584.1 1814480 R 512566 CDS YP_002038585.1 194396932 6478926 complement(1815577..1816314) 1 NC_011072.1 identified by match to protein family HMM PF01061; hypothetical protein 1816314 6478926 SPG_1904 Streptococcus pneumoniae G54 hypothetical protein YP_002038585.1 1815577 R 512566 CDS YP_002038586.1 194397566 6479796 complement(1816316..1817200) 1 NC_011072.1 identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 1817200 6479796 SPG_1905 Streptococcus pneumoniae G54 ABC transporter ATP-binding protein YP_002038586.1 1816316 R 512566 CDS YP_002038587.1 194397323 6479191 complement(1817187..1817381) 1 NC_011072.1 hypothetical protein 1817381 6479191 SPG_1906 Streptococcus pneumoniae G54 hypothetical protein YP_002038587.1 1817187 R 512566 CDS YP_002038588.1 194397286 6480220 complement(1817378..1817584) 1 NC_011072.1 hypothetical protein 1817584 6480220 SPG_1907 Streptococcus pneumoniae G54 hypothetical protein YP_002038588.1 1817378 R 512566 CDS YP_002038589.1 194397079 6480605 complement(1824265..1824744) 1 NC_011072.1 transcriptional regulator ComX2 1824744 6480605 SPG_1922 Streptococcus pneumoniae G54 transcriptional regulator ComX2 YP_002038589.1 1824265 R 512566 CDS YP_002038590.1 194398075 6479633 complement(1824866..1825402) 1 NC_011072.1 Modulates Rho-dependent transcription termination; transcription antitermination protein NusG 1825402 nusG 6479633 nusG Streptococcus pneumoniae G54 transcription antitermination protein NusG YP_002038590.1 1824866 R 512566 CDS YP_002038591.1 194397465 6479468 complement(1825457..1825633) 1 NC_011072.1 forms a complex with SecY and SecG; SecYEG forms a putative protein-conducting channel to which secA binds and translocates targeted polypeptides across the cytoplasmic membrane, a process driven by ATP and a proton-motive force; preprotein translocase subunit SecE 1825633 secE 6479468 secE Streptococcus pneumoniae G54 preprotein translocase subunit SecE YP_002038591.1 1825457 R 512566 CDS YP_002038592.1 194396871 6480194 complement(1825848..1828043) 1 NC_011072.1 identified by match to protein family HMM PF00905; match to protein family HMM PF00912; match to protein family HMM TIGR02074; penicillin-binding protein 2A 1828043 6480194 SPG_1925 Streptococcus pneumoniae G54 penicillin-binding protein 2A YP_002038592.1 1825848 R 512566 CDS YP_002038593.1 194398411 6478750 1828130..1829005 1 NC_011072.1 identified by match to protein family HMM PF00849; RluD subfamily ribosomal large subunit pseudouridine synthase 1829005 6478750 SPG_1926 Streptococcus pneumoniae G54 RluD subfamily ribosomal large subunit pseudouridine synthase YP_002038593.1 1828130 D 512566 CDS YP_002038594.1 194397348 6480300 complement(1829072..1830079) 1 NC_011072.1 identified by match to protein family HMM PF00044; match to protein family HMM PF02800; match to protein family HMM TIGR01534; glyceraldehyde-3-phosphate dehydrogenase 1830079 gap 6480300 gap Streptococcus pneumoniae G54 glyceraldehyde-3-phosphate dehydrogenase YP_002038594.1 1829072 R 512566 CDS YP_002038595.1 194396771 6480357 complement(1830256..1831089) 1 NC_011072.1 identified by match to protein family HMM PF02687; ABC transporter permease 1831089 6480357 SPG_1928 Streptococcus pneumoniae G54 ABC transporter permease YP_002038595.1 1830256 R 512566 CDS YP_002038596.1 194398320 6479642 complement(1831761..1832138) 1 NC_011072.1 identified by match to protein family HMM PF01710; IS630-Spn1 transposase 1832138 6479642 SPG_1929 Streptococcus pneumoniae G54 IS630-Spn1 transposase YP_002038596.1 1831761 R 512566 CDS YP_002038597.1 194397621 6479034 complement(1832269..1833141) 1 NC_011072.1 catalyzes the formation of pyridine-2,3-dicarboxylate and 5-phospho-alpha-D-ribose 1-diphosphate from nictinate D-ribonucleotide; nicotinate-nucleotide pyrophosphorylase 1833141 nadC 6479034 nadC Streptococcus pneumoniae G54 nicotinate-nucleotide pyrophosphorylase YP_002038597.1 1832269 R 512566 CDS YP_002038598.1 194397180 6479416 1833378..1834688 1 NC_011072.1 identified by match to protein family HMM PF03600; match to protein family HMM PF07158; hypothetical protein 1834688 6479416 SPG_1931 Streptococcus pneumoniae G54 hypothetical protein YP_002038598.1 1833378 D 512566 CDS YP_002038599.1 194397586 6479249 complement(1835054..1835185) 1 NC_011072.1 hypothetical protein 1835185 6479249 SPG_1932 Streptococcus pneumoniae G54 hypothetical protein YP_002038599.1 1835054 R 512566 CDS YP_002038600.1 194397124 6478951 complement(1835707..1836435) 1 NC_011072.1 identified by match to protein family HMM PF00392; match to protein family HMM PF07702; GntR family transcriptional regulator 1836435 6478951 SPG_1933 Streptococcus pneumoniae G54 GntR family transcriptional regulator YP_002038600.1 1835707 R 512566 CDS YP_002038601.1 194398575 6479632 1836593..1838002 1 NC_011072.1 identified by match to protein family HMM PF00232; glycosyl hydrolase family protein 1838002 6479632 SPG_1934 Streptococcus pneumoniae G54 glycosyl hydrolase family protein YP_002038601.1 1836593 D 512566 CDS YP_002038602.1 194398059 6478984 1838020..1839315 1 NC_011072.1 identified by match to protein family HMM PF02378; match to protein family HMM TIGR00410; PTS system transporter subunit IIC 1839315 6478984 SPG_1935 Streptococcus pneumoniae G54 PTS system transporter subunit IIC YP_002038602.1 1838020 D 512566 CDS YP_002038603.1 194397875 6478693 1839320..1839628 1 NC_011072.1 identified by match to protein family HMM PF02302; PTS system transporter subunit IIB 1839628 6478693 SPG_1936 Streptococcus pneumoniae G54 PTS system transporter subunit IIB YP_002038603.1 1839320 D 512566 CDS YP_002038604.1 194397387 6480731 1839625..1839933 1 NC_011072.1 identified by match to protein family HMM PF02255; PTS system transporter subunit IIA 1839933 6480731 SPG_1937 Streptococcus pneumoniae G54 PTS system transporter subunit IIA YP_002038604.1 1839625 D 512566 CDS YP_002038605.1 194396836 6480314 complement(1840722..1843373) 1 NC_011072.1 identified by match to protein family HMM PF00465; bifunctional acetaldehyde-CoA/alcohol dehydrogenase 1843373 6480314 SPG_1938 Streptococcus pneumoniae G54 bifunctional acetaldehyde-CoA/alcohol dehydrogenase YP_002038605.1 1840722 R 512566 CDS YP_002038606.1 194398374 6479192 complement(1843576..1843713) 1 NC_011072.1 identified by glimmer; putative; hypothetical protein 1843713 6479192 SPG_1939 Streptococcus pneumoniae G54 hypothetical protein YP_002038606.1 1843576 R 512566 CDS YP_002038607.1 194398135 6478851 complement(1843673..1844083) 1 NC_011072.1 identified by glimmer; putative; hypothetical protein 1844083 6478851 SPG_1940 Streptococcus pneumoniae G54 hypothetical protein YP_002038607.1 1843673 R 512566 CDS YP_002038608.1 194397641 6480326 complement(1844085..1844513) 1 NC_011072.1 identified by match to protein family HMM PF01451; phosphotyrosine protein phosphatase 1844513 6480326 SPG_1941 Streptococcus pneumoniae G54 phosphotyrosine protein phosphatase YP_002038608.1 1844085 R 512566 CDS YP_002038609.1 194396772 6479207 complement(1844559..1844858) 1 NC_011072.1 member of preprotein translocase; forms a heterotrimer with SecD and SecF; links the SecD/SecF/YajC/YidC complex with the SecY/SecE/SecG complex; preprotein translocase subunit YajC 1844858 yajC 6479207 yajC Streptococcus pneumoniae G54 preprotein translocase subunit YajC YP_002038609.1 1844559 R 512566 CDS YP_002038610.1 194398473 6479890 complement(1844975..1846951) 1 NC_011072.1 catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase; transketolase 1846951 tktA 6479890 tktA Streptococcus pneumoniae G54 transketolase YP_002038610.1 1844975 R 512566 CDS YP_002038611.1 194398474 6480613 complement(1847064..1848155) 1 NC_011072.1 putative L-ascorbate 6-phosphate lactonase 1848155 6480613 SPG_1944 Streptococcus pneumoniae G54 putative L-ascorbate 6-phosphate lactonase YP_002038611.1 1847064 R 512566 CDS YP_002038612.1 194397859 6480614 complement(1848267..1849940) 1 NC_011072.1 identified by match to protein family HMM PF00874; match to protein family HMM PF08279; BglG family transcriptional regulator 1849940 6480614 SPG_1945 Streptococcus pneumoniae G54 BglG family transcriptional regulator YP_002038612.1 1848267 R 512566 CDS YP_002038613.1 194396997 6480102 complement(1850117..1850575) 1 NC_011072.1 contains potential frameshift; identified by match to protein family HMM PF00596; L-ribulose-5-phosphate 4-epimerase 1850575 6480102 SPG_1946 Streptococcus pneumoniae G54 L-ribulose-5-phosphate 4-epimerase YP_002038613.1 1850117 R 512566 CDS YP_002038614.1 194398567 6479826 complement(1850562..1850822) 1 NC_011072.1 contains potential frameshift; L-ribulose-5-phosphate 4-epimerase 1850822 6479826 SPG_1947 Streptococcus pneumoniae G54 L-ribulose-5-phosphate 4-epimerase YP_002038614.1 1850562 R 512566 CDS YP_002038615.1 194397684 6478815 complement(1850824..1851687) 1 NC_011072.1 L-xylulose 5-phosphate 3-epimerase activity not yet demonstrated; may be involved in the utilization of 2,3-diketo-L-gulonate; putative L-xylulose 5-phosphate 3-epimerase 1851687 6478815 SPG_1948 Streptococcus pneumoniae G54 putative L-xylulose 5-phosphate 3-epimerase YP_002038615.1 1850824 R 512566 CDS YP_002038616.1 194396689 6479341 complement(1851691..1852356) 1 NC_011072.1 catalyzes the formation of L-xylulose-5-phosphate from 3-keto-L-gulonate-6-phosphate in anaerobic L-ascorbate utilization; 3-keto-L-gulonate-6-phosphate decarboxylase 1852356 ulaD 6479341 ulaD Streptococcus pneumoniae G54 3-keto-L-gulonate-6-phosphate decarboxylase YP_002038616.1 1851691 R 512566 CDS YP_002038617.1 194398728 6479651 complement(1852373..1852858) 1 NC_011072.1 identified by match to protein family HMM PF00359; PTS system transporter subunit IIA 1852858 6479651 SPG_1950 Streptococcus pneumoniae G54 PTS system transporter subunit IIA YP_002038617.1 1852373 R 512566 CDS YP_002038618.1 194398112 6479581 complement(1852935..1853216) 1 NC_011072.1 identified by match to protein family HMM PF02302; PTS system transporter subunit IIB 1853216 6479581 SPG_1951 Streptococcus pneumoniae G54 PTS system transporter subunit IIB YP_002038618.1 1852935 R 512566 CDS YP_002038619.1 194397518 6480482 complement(1853239..1854696) 1 NC_011072.1 membrane component; functions with enzymes IIB (sgaB; ulaB) and IIA (sgaA; ulaC) enzyme I and HPr for anaerobic utilization and uptake of L-ascorbate; sgaTBA are regulated by yifQ as well as Crp and Fnr; PTS system ascorbate-specific transporter subunit IIC 1854696 6480482 SPG_1952 Streptococcus pneumoniae G54 PTS system ascorbate-specific transporter subunit IIC YP_002038619.1 1853239 R 512566 CDS YP_002038620.1 194396913 6478893 complement(1854825..1855448) 1 NC_011072.1 hypothetical protein 1855448 6478893 SPG_1953 Streptococcus pneumoniae G54 hypothetical protein YP_002038620.1 1854825 R 512566 CDS YP_002038621.1 194398721 6479861 complement(1855499..1856485) 1 NC_011072.1 identified by glimmer; putative; hypothetical protein 1856485 6479861 SPG_1954 Streptococcus pneumoniae G54 hypothetical protein YP_002038621.1 1855499 R 512566 CDS YP_002038622.1 194398180 6479092 complement(1856504..1857328) 1 NC_011072.1 identified by match to protein family HMM PF02096; SpoIIIJ family protein 1857328 6479092 SPG_1955 Streptococcus pneumoniae G54 SpoIIIJ family protein YP_002038622.1 1856504 R 512566 CDS YP_002038623.1 194397253 6480520 complement(1857303..1857674) 1 NC_011072.1 protein component of RNaseP which catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'terminus; this enzyme also cleaves other RNA substrates; ribonuclease P 1857674 rnpA 6480520 rnpA Streptococcus pneumoniae G54 ribonuclease P YP_002038623.1 1857303 R 512566 CDS YP_002038624.1 194396673 6478735 complement(1857691..1857822) 1 NC_011072.1 hypothetical protein 1857822 6478735 SPG_1957 Streptococcus pneumoniae G54 hypothetical protein YP_002038624.1 1857691 R 512566 CDS YP_002038625.1 194398458 6480477 complement(1857823..1859013) 1 NC_011072.1 AckA utilizes acetate and can acetylate CheY which increases signal strength during flagellar rotation; utilizes magnesium and ATP; also involved in conversion of acetate to aceyl-CoA; acetate kinase 1859013 ackA 6480477 ackA Streptococcus pneumoniae G54 acetate kinase YP_002038625.1 1857823 R 512566 CDS YP_002038626.1 194397889 6480739 complement(1859064..1860017) 1 NC_011072.1 hypothetical protein 1860017 6480739 SPG_1959 Streptococcus pneumoniae G54 hypothetical protein YP_002038626.1 1859064 R 512566 CDS YP_002038627.1 194398650 6480564 complement(1860078..1860458) 1 NC_011072.1 identified by glimmer; putative; hypothetical protein 1860458 6480564 SPG_1960 Streptococcus pneumoniae G54 hypothetical protein YP_002038627.1 1860078 R 512566 CDS YP_002038628.1 194397034 6479357 complement(1860490..1860672) 1 NC_011072.1 hypothetical protein 1860672 6479357 SPG_1961 Streptococcus pneumoniae G54 hypothetical protein YP_002038628.1 1860490 R 512566 CDS YP_002038629.1 194396646 6480046 complement(1860809..1861222) 1 NC_011072.1 hypothetical protein 1861222 6480046 SPG_1962 Streptococcus pneumoniae G54 hypothetical protein YP_002038629.1 1860809 R 512566 CDS YP_002038630.1 194397219 6479929 complement(1861200..1861661) 1 NC_011072.1 hypothetical protein 1861661 6479929 SPG_1963 Streptococcus pneumoniae G54 hypothetical protein YP_002038630.1 1861200 R 512566 CDS YP_002038631.1 194397981 6480521 complement(1861624..1861926) 1 NC_011072.1 identified by glimmer; putative; hypothetical protein 1861926 6480521 SPG_1964 Streptococcus pneumoniae G54 hypothetical protein YP_002038631.1 1861624 R 512566 CDS YP_002038632.1 194398424 6479315 complement(1861889..1862293) 1 NC_011072.1 identified by match to protein family HMM TIGR02532; competence protein CglD 1862293 6479315 SPG_1965 Streptococcus pneumoniae G54 competence protein CglD YP_002038632.1 1861889 R 512566 CDS YP_002038633.1 194396983 6480074 complement(1862286..1862612) 1 NC_011072.1 identified by match to protein family HMM PF07963; match to protein family HMM TIGR02532; competence protein CglC 1862612 6480074 SPG_1966 Streptococcus pneumoniae G54 competence protein CglC YP_002038633.1 1862286 R 512566 CDS YP_002038634.1 194397467 6480813 complement(1862614..1863630) 1 NC_011072.1 identified by match to protein family HMM PF00482; competence protein CglB 1863630 6480813 SPG_1967 Streptococcus pneumoniae G54 competence protein CglB YP_002038634.1 1862614 R 512566 CDS YP_002038635.1 194397093 6480196 complement(1863578..1864519) 1 NC_011072.1 identified by match to protein family HMM PF00437; competence protein CglA 1864519 6480196 SPG_1968 Streptococcus pneumoniae G54 competence protein CglA YP_002038635.1 1863578 R 512566 CDS YP_002038636.1 194397457 6479842 complement(1864595..1864960) 1 NC_011072.1 identified by match to protein family HMM PF06279; hypothetical protein 1864960 6479842 SPG_1969 Streptococcus pneumoniae G54 hypothetical protein YP_002038636.1 1864595 R 512566 CDS YP_002038637.1 194398409 6479813 complement(1865111..1866169) 1 NC_011072.1 identified by match to protein family HMM PF00107; match to protein family HMM PF08240; alcohol dehydrogenase 1866169 6479813 SPG_1970 Streptococcus pneumoniae G54 alcohol dehydrogenase YP_002038637.1 1865111 R 512566 CDS YP_002038638.1 194397751 6480298 complement(1866332..1867483) 1 NC_011072.1 identified by match to protein family HMM PF01979; match to protein family HMM TIGR00221; N-acetylglucosamine-6-phosphate deacetylase 1867483 nagA 6480298 nagA Streptococcus pneumoniae G54 N-acetylglucosamine-6-phosphate deacetylase YP_002038638.1 1866332 R 512566 CDS YP_002038639.1 194396662 6480251 complement(1867636..1869453) 1 NC_011072.1 identified by match to protein family HMM PF01757; putative acyltransferase 1869453 6480251 SPG_1972 Streptococcus pneumoniae G54 putative acyltransferase YP_002038639.1 1867636 R 512566 CDS YP_002038640.1 194398456 6479672 complement(1869554..1870696) 1 NC_011072.1 Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr); queuine tRNA-ribosyltransferase 1870696 tgt 6479672 tgt Streptococcus pneumoniae G54 queuine tRNA-ribosyltransferase YP_002038640.1 1869554 R 512566 CDS YP_002038641.1 194398137 6480714 1870826..1871683 1 NC_011072.1 identified by match to protein family HMM PF06161; hypothetical protein 1871683 6480714 SPG_1974 Streptococcus pneumoniae G54 hypothetical protein YP_002038641.1 1870826 D 512566 CDS YP_002038642.1 194397257 6480120 complement(1871711..1872355) 1 NC_011072.1 catalyzes the removal of 5-oxoproline from various penultimate amino acid residues except L-proline; pyrrolidone-carboxylate peptidase 1872355 6480120 SPG_1975 Streptococcus pneumoniae G54 pyrrolidone-carboxylate peptidase YP_002038642.1 1871711 R 512566 CDS YP_002038643.1 194397704 6479875 complement(1872462..1872821) 1 NC_011072.1 identified by match to protein family HMM PF06993; hypothetical protein 1872821 6479875 SPG_1976 Streptococcus pneumoniae G54 hypothetical protein YP_002038643.1 1872462 R 512566 CDS YP_002038644.1 194397050 6480582 complement(1872832..1873116) 1 NC_011072.1 MarR family transcriptional regulator 1873116 6480582 SPG_1977 Streptococcus pneumoniae G54 MarR family transcriptional regulator YP_002038644.1 1872832 R 512566 CDS YP_002038645.1 194398600 6479864 complement(1873684..1874796) 1 NC_011072.1 identified by match to protein family HMM PF01476; LysM domain-containing protein 1874796 6479864 SPG_1978 Streptococcus pneumoniae G54 LysM domain-containing protein YP_002038645.1 1873684 R 512566 CDS YP_002038646.1 194397989 6479610 complement(1874962..1875582) 1 NC_011072.1 identified by match to protein family HMM PF00702; match to protein family HMM TIGR01549; haloacid dehalogenase-like hydrolase 1875582 6479610 SPG_1979 Streptococcus pneumoniae G54 haloacid dehalogenase-like hydrolase YP_002038646.1 1874962 R 512566 CDS YP_002038647.1 194398323 6479210 complement(1875586..1876866) 1 NC_011072.1 identified by match to protein family HMM PF01554; match to protein family HMM TIGR00797; MATE efflux family protein 1876866 6479210 SPG_1980 Streptococcus pneumoniae G54 MATE efflux family protein YP_002038647.1 1875586 R 512566 CDS YP_002038648.1 194396672 6478651 complement(1876927..1878411) 1 NC_011072.1 catalyzes the formation of L-threonine from O-phospho-L-homoserine; threonine synthase 1878411 thrC 6478651 thrC Streptococcus pneumoniae G54 threonine synthase YP_002038648.1 1876927 R 512566 CDS YP_002038649.1 194397241 6479845 complement(1878487..1879764) 1 NC_011072.1 hypothetical protein 1879764 6479845 SPG_1982 Streptococcus pneumoniae G54 hypothetical protein YP_002038649.1 1878487 R 512566 CDS YP_002038650.1 194397983 6480337 complement(1880027..1880275) 1 NC_011072.1 identified by glimmer; putative; hypothetical protein 1880275 6480337 SPG_1983 Streptococcus pneumoniae G54 hypothetical protein YP_002038650.1 1880027 R 512566 CDS YP_002038651.1 194396959 6478641 1880435..1880911 1 NC_011072.1 identified by glimmer; putative; hypothetical protein 1880911 6478641 SPG_1984 Streptococcus pneumoniae G54 hypothetical protein YP_002038651.1 1880435 D 512566 CDS YP_002038652.1 194397579 6480021 1881082..1881636 1 NC_011072.1 identified by glimmer; putative; hypothetical protein 1881636 6480021 SPG_1985 Streptococcus pneumoniae G54 hypothetical protein YP_002038652.1 1881082 D 512566 CDS YP_002038653.1 194398196 6479369 1882020..1882295 1 NC_011072.1 hypothetical protein 1882295 6479369 SPG_1986 Streptococcus pneumoniae G54 hypothetical protein YP_002038653.1 1882020 D 512566 CDS YP_002038654.1 194398664 6480515 1882409..1883542 1 NC_011072.1 identified by match to protein family HMM PF00589; phage integrase family site-specific recombinase 1883542 6480515 SPG_1987 Streptococcus pneumoniae G54 phage integrase family site-specific recombinase YP_002038654.1 1882409 D 512566 CDS YP_002038655.1 194396971 6478753 1883583..1884020 1 NC_011072.1 identified by glimmer; putative; hypothetical protein 1884020 6478753 SPG_1988 Streptococcus pneumoniae G54 hypothetical protein YP_002038655.1 1883583 D 512566 CDS YP_002038656.1 194397563 6480338 1884236..1884472 1 NC_011072.1 identified by glimmer; putative; hypothetical protein 1884472 6480338 SPG_1989 Streptococcus pneumoniae G54 hypothetical protein YP_002038656.1 1884236 D 512566 CDS YP_002038657.1 194398430 6479515 1884465..1885196 1 NC_011072.1 identified by match to protein family HMM PF00149; Ser/Thr protein phosphatase family protein 1885196 6479515 SPG_1990 Streptococcus pneumoniae G54 Ser/Thr protein phosphatase family protein YP_002038657.1 1884465 D 512566 CDS YP_002038658.1 194398198 6478781 complement(1891662..1892096) 1 NC_011072.1 identified by match to protein family HMM PF00383; cytidine/deoxycytidylate deaminase family protein 1892096 6478781 SPG_2007 Streptococcus pneumoniae G54 cytidine/deoxycytidylate deaminase family protein YP_002038658.1 1891662 R 512566 CDS YP_002038659.1 194397703 6480517 complement(1892110..1893570) 1 NC_011072.1 Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation; glutamyl-tRNA synthetase 1893570 gltX 6480517 gltX Streptococcus pneumoniae G54 glutamyl-tRNA synthetase YP_002038659.1 1892110 R 512566 CDS YP_002038660.1 194397071 6480581 complement(1893694..1895043) 1 NC_011072.1 functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis; catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate; member of PGI family; glucose-6-phosphate isomerase 1895043 pgi 6480581 pgi Streptococcus pneumoniae G54 glucose-6-phosphate isomerase YP_002038660.1 1893694 R 512566 CDS YP_002038661.1 194398347 6479799 complement(1895030..1895209) 1 NC_011072.1 hypothetical protein 1895209 6479799 SPG_2010 Streptococcus pneumoniae G54 hypothetical protein YP_002038661.1 1895030 R 512566 CDS YP_002038662.1 194397952 6480408 complement(1895213..1895902) 1 NC_011072.1 identified by match to protein family HMM PF00117; match to protein family HMM PF07722; glutamine amidotransferase 1895902 6480408 SPG_2011 Streptococcus pneumoniae G54 glutamine amidotransferase YP_002038662.1 1895213 R 512566 CDS YP_002038663.1 194397325 6478685 complement(1896041..1897807) 1 NC_011072.1 identified by match to protein family HMM PF00005; match to protein family HMM PF00664; ABC transporter ATP-binding protein 1897807 6478685 SPG_2012 Streptococcus pneumoniae G54 ABC transporter ATP-binding protein YP_002038663.1 1896041 R 512566 CDS YP_002038664.1 194397522 6479870 1898059..1898268 1 NC_011072.1 transposase 1898268 6479870 SPG_2013 Streptococcus pneumoniae G54 transposase YP_002038664.1 1898059 D 512566 CDS YP_002038665.1 194396929 6478991 complement(1898599..1900293) 1 NC_011072.1 identified by match to protein family HMM PF00005; match to protein family HMM PF00664; ABC transporter ATP-binding/permease 1900293 6478991 SPG_2014 Streptococcus pneumoniae G54 ABC transporter ATP-binding/permease YP_002038665.1 1898599 R 512566 CDS YP_002038666.1 194397405 6479899 complement(1900440..1902974) 1 NC_011072.1 This protein performs the mismatch recognition step during the DNA repair process; DNA mismatch repair protein MutS 1902974 6479899 SPG_2015 Streptococcus pneumoniae G54 DNA mismatch repair protein MutS YP_002038666.1 1900440 R 512566 CDS YP_002038667.1 194396778 6480156 complement(1903025..1903471) 1 NC_011072.1 identified by match to protein family HMM PF01316; match to protein family HMM PF02863; match to protein family HMM TIGR01529; arginine repressor 1903471 argR2 6480156 argR2 Streptococcus pneumoniae G54 arginine repressor YP_002038667.1 1903025 R 512566 CDS YP_002038668.1 194398354 6479671 1903607..1905298 1 NC_011072.1 catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase; arginyl-tRNA synthetase 1905298 argS 6479671 argS Streptococcus pneumoniae G54 arginyl-tRNA synthetase YP_002038668.1 1903607 D 512566 CDS YP_002038669.1 194397842 6479906 complement(1905489..1905959) 1 NC_011072.1 identified by match to protein family HMM PF01609; transposase 1905959 6479906 SPG_2018 Streptococcus pneumoniae G54 transposase YP_002038669.1 1905489 R 512566 CDS YP_002038670.1 194397712 6480118 1906032..1906517 1 NC_011072.1 identified by match to protein family HMM PF06172; hypothetical protein 1906517 6480118 SPG_2019 Streptococcus pneumoniae G54 hypothetical protein YP_002038670.1 1906032 D 512566 CDS YP_002038671.1 194397101 6480657 1906601..1907308 1 NC_011072.1 Novak, J Bacteriol. 1999 181(4):1126-33.; identified by match to protein family HMM PF00072; match to protein family HMM PF00486; response regulator PnpR 1907308 pnpR 6480657 pnpR Streptococcus pneumoniae G54 response regulator PnpR YP_002038671.1 1906601 D 512566 CDS YP_002038672.1 194398634 6480726 1907309..1908640 1 NC_011072.1 identified by match to protein family HMM PF00512; match to protein family HMM PF02518; histidine kinase PnpS 1908640 pnpS 6480726 pnpS Streptococcus pneumoniae G54 histidine kinase PnpS YP_002038672.1 1907309 D 512566 CDS YP_002038673.1 194398078 6479389 1908807..1909682 1 NC_011072.1 ABC transporter binding protein 1909682 6479389 SPG_2022 Streptococcus pneumoniae G54 ABC transporter binding protein YP_002038673.1 1908807 D 512566 CDS YP_002038674.1 194397692 6479006 1909800..1910663 1 NC_011072.1 identified by match to protein family HMM PF00528; match to protein family HMM TIGR02138; ABC transporter permease 1910663 6479006 SPG_2023 Streptococcus pneumoniae G54 ABC transporter permease YP_002038674.1 1909800 D 512566 CDS YP_002038675.1 194397089 6479082 1910656..1911471 1 NC_011072.1 identified by match to protein family HMM PF00528; match to protein family HMM TIGR00974; ABC transporter permease 1911471 6479082 SPG_2024 Streptococcus pneumoniae G54 ABC transporter permease YP_002038675.1 1910656 D 512566 CDS YP_002038676.1 194398521 6479957 1911473..1912225 1 NC_011072.1 ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation; phosphate transporter ATP-binding protein 1912225 6479957 SPG_2025 Streptococcus pneumoniae G54 phosphate transporter ATP-binding protein YP_002038676.1 1911473 D 512566 CDS YP_002038677.1 194398460 6480653 1912240..1912890 1 NC_011072.1 identified by match to protein family HMM PF01895; match to protein family HMM TIGR02135; phosphate transport system regulatory protein 1912890 6480653 SPG_2026 Streptococcus pneumoniae G54 phosphate transport system regulatory protein YP_002038677.1 1912240 D 512566 CDS YP_002038678.1 194397663 6480773 1912958..1913383 1 NC_011072.1 IS1380-Spn1 transposase 1913383 6480773 SPG_2027 Streptococcus pneumoniae G54 IS1380-Spn1 transposase YP_002038678.1 1912958 D 512566 CDS YP_002038679.1 194398142 6479593 complement(1913557..1913937) 1 NC_011072.1 identified by glimmer; putative; hypothetical protein 1913937 6479593 SPG_2028 Streptococcus pneumoniae G54 hypothetical protein YP_002038679.1 1913557 R 512566 CDS YP_002038680.1 194398311 6480636 1914149..1915165 1 NC_011072.1 catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate; NAD(P)H-dependent glycerol-3-phosphate dehydrogenase 1915165 gpsA 6480636 gpsA Streptococcus pneumoniae G54 NAD(P)H-dependent glycerol-3-phosphate dehydrogenase YP_002038680.1 1914149 D 512566 CDS YP_002038681.1 194397153 6479021 1915187..1916086 1 NC_011072.1 identified by match to protein family HMM PF00483; match to protein family HMM TIGR01099; UTP-glucose-1-phosphate uridylyltransferase 1916086 galU 6479021 galU Streptococcus pneumoniae G54 UTP-glucose-1-phosphate uridylyltransferase YP_002038681.1 1915187 D 512566 CDS YP_002038682.1 194397379 6479015 complement(1916153..1916830) 1 NC_011072.1 identified by match to protein family HMM PF01694; S54 (rhomboid) family peptidase 1916830 6479015 SPG_2031 Streptococcus pneumoniae G54 S54 (rhomboid) family peptidase YP_002038682.1 1916153 R 512566 CDS YP_002038683.1 194397866 6479836 complement(1916814..1917353) 1 NC_011072.1 identified by match to protein family HMM PF01812; match to protein family HMM TIGR02727; 5-formyltetrahydrofolate cyclo-ligase family protein 1917353 6479836 SPG_2032 Streptococcus pneumoniae G54 5-formyltetrahydrofolate cyclo-ligase family protein YP_002038683.1 1916814 R 512566 CDS YP_002038684.1 194396989 6480597 complement(1917365..1918495) 1 NC_011072.1 identified by match to protein family HMM PF01546; match to protein family HMM PF07687; match to protein family HMM TIGR01891; M20/M25/M40 family peptidase 1918495 6480597 SPG_2033 Streptococcus pneumoniae G54 M20/M25/M40 family peptidase YP_002038684.1 1917365 R 512566 CDS YP_002038685.1 194397474 6479784 complement(1918563..1919261) 1 NC_011072.1 identified by match to protein family HMM PF00132; match to protein family HMM PF08503; 2,3,4, 5-tetrahydropyridine-2-carboxylate-aminotransferase 1919261 dapD 6479784 dapD Streptococcus pneumoniae G54 2,3,4, 5-tetrahydropyridine-2-carboxylate-aminotransferase YP_002038685.1 1918563 R 512566 CDS YP_002038686.1 194396714 6480736 complement(1919492..1920403) 1 NC_011072.1 identified by match to protein family HMM PF00892; hypothetical protein 1920403 6480736 SPG_2035 Streptococcus pneumoniae G54 hypothetical protein YP_002038686.1 1919492 R 512566 CDS YP_002038687.1 194397279 6479649 complement(1920468..1922933) 1 NC_011072.1 identified by match to protein family HMM PF00905; match to protein family HMM PF00912; penicillin-binding protein 1B 1922933 6479649 SPG_2036 Streptococcus pneumoniae G54 penicillin-binding protein 1B YP_002038687.1 1920468 R 512566 CDS YP_002038688.1 194398136 6478699 1923075..1924331 1 NC_011072.1 catalyzes the formation of tyrosyl-tRNA(Tyr) from tyrosine and tRNA(Tyr); tyrosyl-tRNA synthetase 1924331 tyrS 6478699 tyrS Streptococcus pneumoniae G54 tyrosyl-tRNA synthetase YP_002038688.1 1923075 D 512566 CDS YP_002038689.1 194398730 6480327 complement(1924409..1926472) 1 NC_011072.1 identified by match to protein family HMM PF00122; match to protein family HMM PF00702; match to protein family HMM TIGR01494; match to protein family HMM TIGR01525; E1-E2 family cation-transporting ATPase 1926472 6480327 SPG_2038 Streptococcus pneumoniae G54 E1-E2 family cation-transporting ATPase YP_002038689.1 1924409 R 512566 CDS YP_002038690.1 194398511 6478976 complement(1926474..1926752) 1 NC_011072.1 hypothetical protein 1926752 6478976 SPG_2039 Streptococcus pneumoniae G54 hypothetical protein YP_002038690.1 1926474 R 512566 CDS YP_002038691.1 194397533 6480211 1926904..1927752 1 NC_011072.1 identified by match to protein family HMM PF08241; methyltransferase 1927752 6480211 SPG_2040 Streptococcus pneumoniae G54 methyltransferase YP_002038691.1 1926904 D 512566 CDS YP_002038692.1 194397291 6479478 complement(1928358..1928564) 1 NC_011072.1 hypothetical protein 1928564 6479478 SPG_2041 Streptococcus pneumoniae G54 hypothetical protein YP_002038692.1 1928358 R 512566 CDS YP_002038693.1 194397928 6478694 1928686..1929213 1 NC_011072.1 hypothetical protein 1929213 6478694 SPG_2042 Streptococcus pneumoniae G54 hypothetical protein YP_002038693.1 1928686 D 512566 CDS YP_002038694.1 194398273 6478784 complement(1930258..1932516) 1 NC_011072.1 Spatafora,G.A. 1992 Inf.& Imm.; identified by match to protein family HMM PF00343; match to protein family HMM TIGR02093; alpha-glucan phosphorylase 1932516 glgP 6478784 glgP Streptococcus pneumoniae G54 alpha-glucan phosphorylase YP_002038694.1 1930258 R 512566 CDS YP_002038695.1 194397151 6479013 complement(1932542..1934059) 1 NC_011072.1 amylomaltase; acts to release glucose from maltodextrins; 4-alpha-glucanotransferase 1934059 malQ 6479013 malQ Streptococcus pneumoniae G54 4-alpha-glucanotransferase YP_002038695.1 1932542 R 512566 CDS YP_002038696.1 194398221 6479994 1934609..1935880 1 NC_011072.1 identified by match to protein family HMM PF01547; maltose/maltodextrin ABC transporter maltose/maltodextrin-binding protein 1935880 malX 6479994 malX Streptococcus pneumoniae G54 maltose/maltodextrin ABC transporter maltose/maltodextrin-binding protein YP_002038696.1 1934609 D 512566 CDS YP_002038697.1 194397428 6479259 1935991..1937283 1 NC_011072.1 identified by match to protein family HMM PF00528; match to protein family HMM PF05154; maltodextrin transport system permease MalC 1937283 malC 6479259 malC Streptococcus pneumoniae G54 maltodextrin transport system permease MalC YP_002038697.1 1935991 D 512566 CDS YP_002038698.1 194397003 6480161 1937285..1938127 1 NC_011072.1 identified by match to protein family HMM PF00528; maltodextrin ABC transporter permease MalD 1938127 malD 6480161 malD Streptococcus pneumoniae G54 maltodextrin ABC transporter permease MalD YP_002038698.1 1937285 D 512566 CDS YP_002038699.1 194398357 6479989 1938380..1939180 1 NC_011072.1 maltodextrose utilization protein MalA 1939180 malA 6479989 malA Streptococcus pneumoniae G54 maltodextrose utilization protein MalA YP_002038699.1 1938380 D 512566 CDS YP_002038700.1 194397742 6479972 1939190..1940176 1 NC_011072.1 identified by match to protein family HMM PF00356; match to protein family HMM PF00532; maltose operon transcriptional 1940176 malR 6479972 malR Streptococcus pneumoniae G54 maltose operon transcriptional YP_002038700.1 1939190 D 512566 CDS YP_002038701.1 194396872 6480385 complement(1940647..1941588) 1 NC_011072.1 identified by match to protein family HMM PF02588; hypothetical protein 1941588 6480385 SPG_2050 Streptococcus pneumoniae G54 hypothetical protein YP_002038701.1 1940647 R 512566 CDS YP_002038702.1 194398266 6478995 complement(1941566..1943329) 1 NC_011072.1 catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes; aspartyl-tRNA synthetase 1943329 aspS 6478995 aspS Streptococcus pneumoniae G54 aspartyl-tRNA synthetase YP_002038702.1 1941566 R 512566 CDS YP_002038703.1 194398147 6479591 complement(1943681..1943911) 1 NC_011072.1 hypothetical protein 1943911 6479591 SPG_2052 Streptococcus pneumoniae G54 hypothetical protein YP_002038703.1 1943681 R 512566 CDS YP_002038704.1 194398344 6479625 complement(1943929..1944570) 1 NC_011072.1 identified by match to protein family HMM PF02517; CAAX amino terminal protease family 1944570 6479625 SPG_2053 Streptococcus pneumoniae G54 CAAX amino terminal protease family YP_002038704.1 1943929 R 512566 CDS YP_002038705.1 194397592 6480258 complement(1944582..1945316) 1 NC_011072.1 hypothetical protein 1945316 6480258 SPG_2054 Streptococcus pneumoniae G54 hypothetical protein YP_002038705.1 1944582 R 512566 CDS YP_002038706.1 194397122 6478704 complement(1945319..1945516) 1 NC_011072.1 hypothetical protein 1945516 6478704 SPG_2055 Streptococcus pneumoniae G54 hypothetical protein YP_002038706.1 1945319 R 512566 CDS YP_002038707.1 194398055 6479795 complement(1945516..1945722) 1 NC_011072.1 identified by match to protein family HMM PF01381; hypothetical protein 1945722 6479795 SPG_2056 Streptococcus pneumoniae G54 hypothetical protein YP_002038707.1 1945516 R 512566 CDS YP_002038708.1 194398578 6478664 complement(1945732..1946046) 1 NC_011072.1 hypothetical protein 1946046 6478664 SPG_2057 Streptococcus pneumoniae G54 hypothetical protein YP_002038708.1 1945732 R 512566 CDS YP_002038709.1 194396786 6479184 complement(1946388..1947677) 1 NC_011072.1 catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG; histidyl-tRNA synthetase 1947677 hisS 6479184 hisS Streptococcus pneumoniae G54 histidyl-tRNA synthetase YP_002038709.1 1946388 R 512566 CDS YP_002038710.1 194397259 6480335 complement(1947755..1949002) 1 NC_011072.1 identified by match to protein family HMM PF07690; major facilitator family transporter 1949002 6480335 SPG_2059 Streptococcus pneumoniae G54 major facilitator family transporter YP_002038710.1 1947755 R 512566 CDS YP_002038711.1 194397732 6479225 complement(1949193..1950044) 1 NC_011072.1 identified by match to protein family HMM TIGR01716; Rgg/GadR/MutR family transcriptional activator 1950044 6479225 SPG_2060 Streptococcus pneumoniae G54 Rgg/GadR/MutR family transcriptional activator YP_002038711.1 1949193 R 512566 CDS YP_002038712.1 194398601 6480701 complement(1950019..1950153) 1 NC_011072.1 hypothetical protein 1950153 6480701 SPG_2061 Streptococcus pneumoniae G54 hypothetical protein YP_002038712.1 1950019 R 512566 CDS YP_002038713.1 194397535 6478941 1950168..1950509 1 NC_011072.1 identified by match to protein family HMM PF01883; hypothetical protein 1950509 6478941 SPG_2062 Streptococcus pneumoniae G54 hypothetical protein YP_002038713.1 1950168 D 512566 CDS YP_002038714.1 194398502 6478791 complement(1950763..1952466) 1 NC_011072.1 catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis; dihydroxy-acid dehydratase 1952466 6478791 SPG_2063 Streptococcus pneumoniae G54 dihydroxy-acid dehydratase YP_002038714.1 1950763 R 512566 CDS YP_002038715.1 194396715 6480474 complement(1952699..1953631) 1 NC_011072.1 identified by match to protein family HMM PF02779; match to protein family HMM PF02780; transketolase, C-terminal subunit 1953631 6480474 SPG_2064 Streptococcus pneumoniae G54 transketolase, C-terminal subunit YP_002038715.1 1952699 R 512566 CDS YP_002038716.1 194397231 6479817 complement(1953628..1954485) 1 NC_011072.1 identified by match to protein family HMM PF00456; transketolase N-terminal section 1954485 6479817 SPG_2065 Streptococcus pneumoniae G54 transketolase N-terminal section YP_002038716.1 1953628 R 512566 CDS YP_002038717.1 194397901 6479912 complement(1954489..1955835) 1 NC_011072.1 membrane component; functions with enzymes IIB (sgaB; ulaB) and IIA (sgaA; ulaC) enzyme I and HPr for anaerobic utilization and uptake of L-ascorbate; sgaTBA are regulated by yifQ as well as Crp and Fnr; PTS system ascorbate-specific transporter subunit IIC 1955835 ulaA 6479912 ulaA Streptococcus pneumoniae G54 PTS system ascorbate-specific transporter subunit IIC YP_002038717.1 1954489 R 512566 CDS YP_002038718.1 194398293 6479118 complement(1955848..1956132) 1 NC_011072.1 identified by match to protein family HMM PF02302; PTS system transporter subunit IIB 1956132 6479118 SPG_2067 Streptococcus pneumoniae G54 PTS system transporter subunit IIB YP_002038718.1 1955848 R 512566 CDS YP_002038719.1 194396723 6478974 complement(1956136..1956489) 1 NC_011072.1 contains potential frameshift; identified by match to protein family HMM PF00359; PTS system transporter subunit IIA 1956489 6478974 SPG_2068 Streptococcus pneumoniae G54 PTS system transporter subunit IIA YP_002038719.1 1956136 R 512566 CDS YP_002038720.1 194397055 6479956 complement(1956542..1958167) 1 NC_011072.1 contains potential frameshift; identified by match to protein family HMM PF00874; BglG family transcriptional regulator 1958167 6479956 SPG_2069 Streptococcus pneumoniae G54 BglG family transcriptional regulator YP_002038720.1 1956542 R 512566 CDS YP_002038721.1 194397659 6480064 1958358..1958810 1 NC_011072.1 contains potential frameshift; hypothetical protein 1958810 6480064 SPG_2070 Streptococcus pneumoniae G54 hypothetical protein YP_002038721.1 1958358 D 512566 CDS YP_002038722.1 194397357 6479575 1958776..1959366 1 NC_011072.1 contains potential frameshift; hypothetical protein 1959366 6479575 SPG_2071 Streptococcus pneumoniae G54 hypothetical protein YP_002038722.1 1958776 D 512566 CDS YP_002038723.1 194397818 6480399 1959722..1959904 1 NC_011072.1 some L32 proteins have zinc finger motifs consisting of CXXC while others do not; 50S ribosomal protein L32 1959904 rpmF 6480399 rpmF Streptococcus pneumoniae G54 50S ribosomal protein L32 YP_002038723.1 1959722 D 512566 CDS YP_002038724.1 194398314 6480273 1959920..1960069 1 NC_011072.1 in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif; 50S ribosomal protein L33 1960069 rpmG 6480273 rpmG Streptococcus pneumoniae G54 50S ribosomal protein L33 YP_002038724.1 1959920 D 512566 CDS YP_002038725.1 194397162 6479237 complement(1960549..1962354) 1 NC_011072.1 identified by match to protein family HMM PF01473; choline binding protein PcpA 1962354 pcpA 6479237 pcpA Streptococcus pneumoniae G54 choline binding protein PcpA YP_002038725.1 1960549 R 512566 CDS YP_002038726.1 194398098 6479276 1962689..1963054 1 NC_011072.1 identified by match to protein family HMM PF04326; IS1381 transposase 1963054 6479276 SPG_2076 Streptococcus pneumoniae G54 IS1381 transposase YP_002038726.1 1962689 D 512566 CDS YP_002038727.1 194398580 6480642 1963199..1963339 1 NC_011072.1 IS1381 transposase 1963339 6480642 SPG_2077 Streptococcus pneumoniae G54 IS1381 transposase YP_002038727.1 1963199 D 512566 CDS YP_002038728.1 194396889 6478713 1963369..1963668 1 NC_011072.1 transposase 1963668 6478713 SPG_2078 Streptococcus pneumoniae G54 transposase YP_002038728.1 1963369 D 512566 CDS YP_002038729.1 194397375 6479327 complement(1963831..1963995) 1 NC_011072.1 hypothetical protein 1963995 6479327 SPG_2079 Streptococcus pneumoniae G54 hypothetical protein YP_002038729.1 1963831 R 512566 CDS YP_002038730.1 194397791 6480246 complement(1964061..1964192) 1 NC_011072.1 identified by glimmer; putative; hypothetical protein 1964192 6480246 SPG_2080 Streptococcus pneumoniae G54 hypothetical protein YP_002038730.1 1964061 R 512566 CDS YP_002038731.1 194397755 6479946 complement(1964459..1966339) 1 NC_011072.1 identified by match to protein family HMM PF00728; glycosyl hydrolase family protein 1966339 6479946 SPG_2081 Streptococcus pneumoniae G54 glycosyl hydrolase family protein YP_002038731.1 1964459 R 512566 CDS YP_002038732.1 194398397 6479867 complement(1966333..1967202) 1 NC_011072.1 identified by match to protein family HMM PF00480; ROK family protein 1967202 6479867 SPG_2082 Streptococcus pneumoniae G54 ROK family protein YP_002038732.1 1966333 R 512566 CDS YP_002038733.1 194397001 6478898 complement(1967284..1969929) 1 NC_011072.1 identified by match to protein family HMM PF01074; match to protein family HMM PF07748; hypothetical protein 1969929 6478898 SPG_2083 Streptococcus pneumoniae G54 hypothetical protein YP_002038733.1 1967284 R 512566 CDS YP_002038734.1 194397475 6480530 complement(1970020..1971300) 1 NC_011072.1 identified by match to protein family HMM PF06824; hypothetical protein 1971300 6480530 SPG_2084 Streptococcus pneumoniae G54 hypothetical protein YP_002038734.1 1970020 R 512566 CDS YP_002038735.1 194396947 6480737 1971471..1973555 1 NC_011072.1 identified by match to protein family HMM PF07971; match to protein family HMM TIGR01180; alpha-1,2-mannosidase 1973555 6480737 SPG_2085 Streptococcus pneumoniae G54 alpha-1,2-mannosidase YP_002038735.1 1971471 D 512566 CDS YP_002038736.1 194397477 6479902 complement(1973595..1975274) 1 NC_011072.1 identified by glimmer; putative; hypothetical protein 1975274 6479902 SPG_2086 Streptococcus pneumoniae G54 hypothetical protein YP_002038736.1 1973595 R 512566 CDS YP_002038737.1 194397222 6479962 complement(1975318..1975431) 1 NC_011072.1 identified by glimmer; putative; hypothetical protein 1975431 6479962 SPG_2087 Streptococcus pneumoniae G54 hypothetical protein YP_002038737.1 1975318 R 512566 CDS YP_002038738.1 194398644 6480571 1976028..1977257 1 NC_011072.1 catalyzes the degradation of arginine to citruline and ammonia; arginine deiminase 1977257 arcA 6480571 arcA Streptococcus pneumoniae G54 arginine deiminase YP_002038738.1 1976028 D 512566 CDS YP_002038739.1 194398426 6479430 1977315..1978331 1 NC_011072.1 catalyzes the formation of ornithine and carbamylphosphate from citrulline in the arginine catabolic pathway; ornithine carbamoyltransferase 1978331 argF 6479430 argF Streptococcus pneumoniae G54 ornithine carbamoyltransferase YP_002038739.1 1977315 D 512566 CDS YP_002038740.1 194396742 6480076 1978496..1979443 1 NC_011072.1 catalyzes the reversible synthesis of carbamate and ATP from carbamoyl phosphate and ADP; carbamate kinase 1979443 6480076 SPG_2090 Streptococcus pneumoniae G54 carbamate kinase YP_002038740.1 1978496 D 512566 CDS YP_002038741.1 194396744 6480320 1979654..1981165 1 NC_011072.1 identified by match to protein family HMM PF03606; hypothetical protein 1981165 6480320 SPG_2091 Streptococcus pneumoniae G54 hypothetical protein YP_002038741.1 1979654 D 512566 CDS YP_002038742.1 194397630 6479885 1981187..1982518 1 NC_011072.1 identified by match to protein family HMM PF01546; match to protein family HMM TIGR01887; hypothetical protein 1982518 6479885 SPG_2092 Streptococcus pneumoniae G54 hypothetical protein YP_002038742.1 1981187 D 512566 CDS YP_002038743.1 194397858 6478861 complement(1982905..1983195) 1 NC_011072.1 hypothetical protein 1983195 6478861 SPG_2093 Streptococcus pneumoniae G54 hypothetical protein YP_002038743.1 1982905 R 512566 CDS YP_002038744.1 194398480 6480101 complement(1983183..1983434) 1 NC_011072.1 identified by glimmer; putative; hypothetical protein 1983434 6480101 SPG_2094 Streptococcus pneumoniae G54 hypothetical protein YP_002038744.1 1983183 R 512566 CDS YP_002038745.1 194397955 6480550 complement(1983788..1984687) 1 NC_011072.1 identified by match to protein family HMM PF01145; hypothetical protein 1984687 6480550 SPG_2095 Streptococcus pneumoniae G54 hypothetical protein YP_002038745.1 1983788 R 512566 CDS YP_002038746.1 194398423 6479102 complement(1984817..1985968) 1 NC_011072.1 identified by match to protein family HMM PF00465; alcohol dehydrogenase 1985968 6479102 SPG_2096 Streptococcus pneumoniae G54 alcohol dehydrogenase YP_002038746.1 1984817 R 512566 CDS YP_002038747.1 194396793 6480366 complement(1986114..1986395) 1 NC_011072.1 contains potential frameshift; L-fucose isomerase 1986395 6480366 SPG_2097 Streptococcus pneumoniae G54 L-fucose isomerase YP_002038747.1 1986114 R 512566 CDS YP_002038748.1 194397402 6479857 complement(1986365..1987879) 1 NC_011072.1 contains potential frameshift; identified by match to protein family HMM PF02952; match to protein family HMM PF07881; match to protein family HMM PF07882; L-fucose isomerase 1987879 6479857 SPG_2098 Streptococcus pneumoniae G54 L-fucose isomerase YP_002038748.1 1986365 R 512566 CDS YP_002038749.1 194397282 6480611 complement(1987892..1988620) 1 NC_011072.1 contains potential frameshift; identified by match to protein family HMM PF00596; L-fuculose-phosphate aldolase 1988620 6480611 SPG_2099 Streptococcus pneumoniae G54 L-fuculose-phosphate aldolase YP_002038749.1 1987892 R 512566 CDS YP_002038750.1 194397884 6478865 complement(1988635..1989783) 1 NC_011072.1 contains potential frameshift; blood group cleaving endo-beta-galactosidase 1989783 6478865 SPG_2100 Streptococcus pneumoniae G54 blood group cleaving endo-beta-galactosidase YP_002038750.1 1988635 R 512566 CDS YP_002038751.1 194397088 6480036 complement(1989921..1991651) 1 NC_011072.1 contains potential frameshift; identified by match to protein family HMM PF08305; blood group cleaving endo-beta-galactosidase 1991651 6480036 SPG_2101 Streptococcus pneumoniae G54 blood group cleaving endo-beta-galactosidase YP_002038751.1 1989921 R 512566 CDS YP_002038752.1 194396760 6479652 complement(1991662..1993878) 1 NC_011072.1 identified by match to protein family HMM PF02065; glycosyl hydrolase family protein 1993878 6479652 SPG_2102 Streptococcus pneumoniae G54 glycosyl hydrolase family protein YP_002038752.1 1991662 R 512566 CDS YP_002038753.1 194398037 6480048 complement(1993900..1995771) 1 NC_011072.1 identified by glimmer; putative; hypothetical protein 1995771 6480048 SPG_2103 Streptococcus pneumoniae G54 hypothetical protein YP_002038753.1 1993900 R 512566 CDS YP_002038754.1 194397599 6479487 complement(1995777..1997096) 1 NC_011072.1 identified by match to protein family HMM PF01120; alpha-L-fucosidase 1997096 6479487 SPG_2104 Streptococcus pneumoniae G54 alpha-L-fucosidase YP_002038754.1 1995777 R 512566 CDS YP_002038755.1 194398412 6478797 complement(1997093..1997932) 1 NC_011072.1 identified by match to protein family HMM PF00528; ABC transporter ATP-binding/permease 1997932 6478797 SPG_2105 Streptococcus pneumoniae G54 ABC transporter ATP-binding/permease YP_002038755.1 1997093 R 512566 CDS YP_002038756.1 194397939 6480807 complement(1997935..1998864) 1 NC_011072.1 identified by match to protein family HMM PF00528; ABC transporter permease 1998864 6480807 SPG_2106 Streptococcus pneumoniae G54 ABC transporter permease YP_002038756.1 1997935 R 512566 CDS YP_002038757.1 194397206 6479447 complement(1998951..2000243) 1 NC_011072.1 identified by match to protein family HMM PF01547; ABC transporter binding protein 2000243 6479447 SPG_2107 Streptococcus pneumoniae G54 ABC transporter binding protein YP_002038757.1 1998951 R 512566 CDS YP_002038758.1 194396671 6480040 complement(2000272..2001675) 1 NC_011072.1 identified by match to protein family HMM PF00370; L-fuculose kinase FucK 2001675 6480040 SPG_2108 Streptococcus pneumoniae G54 L-fuculose kinase FucK YP_002038758.1 2000272 R 512566 CDS YP_002038759.1 194396661 6479768 2001851..2002624 1 NC_011072.1 identified by match to protein family HMM PF00455; match to protein family HMM PF08220; match to protein family HMM PF08279; DeoR family fucose operon regulator 2002624 6479768 SPG_2109 Streptococcus pneumoniae G54 DeoR family fucose operon regulator YP_002038759.1 2001851 D 512566 CDS YP_002038760.1 194398238 6479726 complement(2003410..2004915) 1 NC_011072.1 identified by match to protein family HMM PF01297; match to protein family HMM PF09223; zinc ABC transporter zinc-binding lipoprotein 2004915 6479726 SPG_2110 Streptococcus pneumoniae G54 zinc ABC transporter zinc-binding lipoprotein YP_002038760.1 2003410 R 512566 CDS YP_002038761.1 194398174 6479202 complement(2004925..2005731) 1 NC_011072.1 identified by match to protein family HMM PF00950; zinc ABC transporter permease 2005731 6479202 SPG_2111 Streptococcus pneumoniae G54 zinc ABC transporter permease YP_002038761.1 2004925 R 512566 CDS YP_002038762.1 194397691 6480735 complement(2005724..2006428) 1 NC_011072.1 identified by match to protein family HMM PF00005; zinc ABC transporter ATP-binding protein 2006428 6480735 SPG_2112 Streptococcus pneumoniae G54 zinc ABC transporter ATP-binding protein YP_002038762.1 2005724 R 512566 CDS YP_002038763.1 194398300 6479081 complement(2006428..2006868) 1 NC_011072.1 identified by match to protein family HMM PF01022; match to protein family HMM PF01047; match to protein family HMM PF01325; match to protein family HMM PF01978; match to protein family HMM PF08279; MarR family transcriptional regulator 2006868 6479081 SPG_2113 Streptococcus pneumoniae G54 MarR family transcriptional regulator YP_002038763.1 2006428 R 512566 CDS YP_002038764.1 194397851 6479456 2006853..2006990 1 NC_011072.1 identified by glimmer; putative; hypothetical protein 2006990 6479456 SPG_2114 Streptococcus pneumoniae G54 hypothetical protein YP_002038764.1 2006853 D 512566 CDS YP_002038765.1 194397807 6480139 complement(2007023..2008291) 1 NC_011072.1 identified by match to protein family HMM PF04914; match to protein family HMM PF04915; match to protein family HMM PF04918; undecaprenol-phosphate-poly(glycerophosphate subunit) D-alanine 2008291 dltD 6480139 dltD Streptococcus pneumoniae G54 undecaprenol-phosphate-poly(glycerophosphate subunit) D-alanine YP_002038765.1 2007023 R 512566 CDS YP_002038766.1 194397333 6480665 complement(2008284..2008523) 1 NC_011072.1 D-alanyl carrier protein subunit; involved in the incorporation of D-alanine into membrane-associated D-alanyl-lipoteichoic acid; D-alanyl carrier protein is the acceptor of activated D-alanine which it donates to a membrane acceptor(D-alanyl transferase) for incorporation into membrane lipoteichoic acid; D-alanine--poly(phosphoribitol) ligase subunit 2 2008523 dltC 6480665 dltC Streptococcus pneumoniae G54 D-alanine--poly(phosphoribitol) ligase subunit 2 YP_002038766.1 2008284 R 512566 CDS YP_002038767.1 194396856 6479908 complement(2008537..2009781) 1 NC_011072.1 identified by match to protein family HMM PF03062; D-alanine transfer from Dcp to undecaprenol-phosphate 2009781 dltB 6479908 dltB Streptococcus pneumoniae G54 D-alanine transfer from Dcp to undecaprenol-phosphate YP_002038767.1 2008537 R 512566 CDS YP_002038768.1 194398571 6478979 complement(2009778..2011328) 1 NC_011072.1 transfers D-alanine to the D-alanyl carrier protein during the incorporation of D-alanine into lipoteichoic acid; D-alanine--poly(phosphoribitol) ligase subunit 1 2011328 dltA 6478979 dltA Streptococcus pneumoniae G54 D-alanine--poly(phosphoribitol) ligase subunit 1 YP_002038768.1 2009778 R 512566 CDS YP_002038769.1 194397987 6479150 complement(2011349..2011480) 1 NC_011072.1 hypothetical protein 2011480 6479150 SPG_2119 Streptococcus pneumoniae G54 hypothetical protein YP_002038769.1 2011349 R 512566 CDS YP_002038770.1 194397398 6479604 complement(2011794..2012972) 1 NC_011072.1 hypothetical protein 2012972 6479604 SPG_2120 Streptococcus pneumoniae G54 hypothetical protein YP_002038770.1 2011794 R 512566 CDS YP_002038771.1 194398091 6480291 complement(2013429..2014706) 1 NC_011072.1 identified by match to protein family HMM PF00078; match to protein family HMM PF08388; putative group II intron protein 2014706 6480291 SPG_2121 Streptococcus pneumoniae G54 putative group II intron protein YP_002038771.1 2013429 R 512566 CDS YP_002038772.1 194397537 6479658 2015947..2016138 1 NC_011072.1 hypothetical protein 2016138 6479658 SPG_2122 Streptococcus pneumoniae G54 hypothetical protein YP_002038772.1 2015947 D 512566 CDS YP_002038773.1 194398260 6479395 complement(2016540..2016686) 1 NC_011072.1 hypothetical protein 2016686 6479395 SPG_2123 Streptococcus pneumoniae G54 hypothetical protein YP_002038773.1 2016540 R 512566 CDS YP_002038774.1 194397779 6479578 2016836..2016961 1 NC_011072.1 identified by glimmer; putative; hypothetical protein 2016961 6479578 SPG_2124 Streptococcus pneumoniae G54 hypothetical protein YP_002038774.1 2016836 D 512566 CDS YP_002038775.1 194397024 6479697 complement(2017040..2017744) 1 NC_011072.1 identified by match to protein family HMM PF00230; match to protein family HMM TIGR00861; glycerol uptake facilitator protein 2017744 6479697 SPG_2125 Streptococcus pneumoniae G54 glycerol uptake facilitator protein YP_002038775.1 2017040 R 512566 CDS YP_002038776.1 194398433 6479982 complement(2017812..2019638) 1 NC_011072.1 identified by match to protein family HMM PF01266; alpha-glycerophosphate oxidase 2019638 6479982 SPG_2126 Streptococcus pneumoniae G54 alpha-glycerophosphate oxidase YP_002038776.1 2017812 R 512566 CDS YP_002038777.1 194398191 6480264 complement(2019680..2021188) 1 NC_011072.1 Converts glycerol and ADP to glycerol-3-phosphate and ADP; glycerol kinase 2021188 glpK 6480264 glpK Streptococcus pneumoniae G54 glycerol kinase YP_002038777.1 2019680 R 512566 CDS YP_002038778.1 194397478 6480780 complement(2021347..2022756) 1 NC_011072.1 identified by match to protein family HMM PF05043; hypothetical protein 2022756 6480780 SPG_2128 Streptococcus pneumoniae G54 hypothetical protein YP_002038778.1 2021347 R 512566 CDS YP_002038779.1 194396767 6479963 2022939..2023811 1 NC_011072.1 becomes active under oxidative stress; four conserved cysteines bind a zinc atom when they are in the reduced state and the enzyme is inactive; oxidative stress results in oxidized cysteines, release of zinc, and binding of Hsp33 to aggregation-prone proteins; forms dimers and higher order oligomers; Hsp33-like chaperonin 2023811 hslO 6479963 hslO Streptococcus pneumoniae G54 Hsp33-like chaperonin YP_002038779.1 2022939 D 512566 CDS YP_002038780.1 194397168 6479958 2023798..2024778 1 NC_011072.1 identified by match to protein family HMM PF00724; match to protein family HMM PF01180; match to protein family HMM PF01207; match to protein family HMM TIGR00737; dihydrouridine synthase 2024778 6479958 SPG_2130 Streptococcus pneumoniae G54 dihydrouridine synthase YP_002038780.1 2023798 D 512566 CDS YP_002038781.1 194398546 6479538 2024874..2025389 1 NC_011072.1 identified by match to protein family HMM PF01527; IS3-Spn1 transposase 2025389 6479538 SPG_2131 Streptococcus pneumoniae G54 IS3-Spn1 transposase YP_002038781.1 2024874 D 512566 CDS YP_002038782.1 194398487 6480106 2025389..2026222 1 NC_011072.1 identified by match to protein family HMM PF00665; IS3-Spn1 transposase 2026222 6480106 SPG_2132 Streptococcus pneumoniae G54 IS3-Spn1 transposase YP_002038782.1 2025389 D 512566 CDS YP_002038783.1 194397935 6479973 2026356..2026874 1 NC_011072.1 IS1167 transposase 2026874 6479973 SPG_2133 Streptococcus pneumoniae G54 IS1167 transposase YP_002038783.1 2026356 D 512566 CDS YP_002038784.1 194397016 6478917 2026871..2027632 1 NC_011072.1 identified by match to protein family HMM PF01610; IS1167 transposase 2027632 6478917 SPG_2134 Streptococcus pneumoniae G54 IS1167 transposase YP_002038784.1 2026871 D 512566 CDS YP_002038785.1 194398341 6480115 complement(2027843..2030152) 1 NC_011072.1 identified by match to protein family HMM PF00746; match to protein family HMM PF04650; match to protein family HMM PF05062; match to protein family HMM TIGR01167; match to protein family HMM TIGR01168; surface protein PspC 2030152 pspC 6480115 pspC Streptococcus pneumoniae G54 surface protein PspC YP_002038785.1 2027843 R 512566 CDS YP_002038786.1 194397605 6480783 complement(2030230..2030757) 1 NC_011072.1 identified by match to protein family HMM PF04140; Isoprenylcysteine carboxyl methyltransferase (ICMT) family 2030757 6480783 SPG_2136 Streptococcus pneumoniae G54 Isoprenylcysteine carboxyl methyltransferase (ICMT) family YP_002038786.1 2030230 R 512566 CDS YP_002038787.1 194397427 6479362 complement(2030852..2032192) 1 NC_011072.1 identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518; histidine kinase 2032192 6479362 SPG_2137 Streptococcus pneumoniae G54 histidine kinase YP_002038787.1 2030852 R 512566 CDS YP_002038788.1 194396684 6480160 complement(2032189..2032842) 1 NC_011072.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00486; response regulator 2032842 6480160 SPG_2138 Streptococcus pneumoniae G54 response regulator YP_002038788.1 2032189 R 512566 CDS YP_002038789.1 194398620 6480059 complement(2033131..2033265) 1 NC_011072.1 identified by glimmer; putative; hypothetical protein 2033265 6480059 SPG_2139 Streptococcus pneumoniae G54 hypothetical protein YP_002038789.1 2033131 R 512566 CDS YP_002038790.1 194397902 6479464 2033282..2033413 1 NC_011072.1 identified by glimmer; putative; hypothetical protein 2033413 6479464 SPG_2140 Streptococcus pneumoniae G54 hypothetical protein YP_002038790.1 2033282 D 512566 CDS YP_002038791.1 194398319 6479119 complement(2033484..2035916) 1 NC_011072.1 identified by match to protein family HMM PF00004; match to protein family HMM PF02861; match to protein family HMM PF07724; match to protein family HMM PF07728; ATP-dependent Clp protease ATP-binding subunit 2035916 6479119 SPG_2141 Streptococcus pneumoniae G54 ATP-dependent Clp protease ATP-binding subunit YP_002038791.1 2033484 R 512566 CDS YP_002038792.1 194397218 6479033 complement(2035918..2036376) 1 NC_011072.1 identified by match to protein family HMM PF05848; transcriptional regulator CtsR 2036376 ctsR 6479033 ctsR Streptococcus pneumoniae G54 transcriptional regulator CtsR YP_002038792.1 2035918 R 512566 CDS YP_002038793.1 194396755 6480575 complement(2036495..2037223) 1 NC_011072.1 identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 2037223 6480575 SPG_2143 Streptococcus pneumoniae G54 ABC transporter ATP-binding protein YP_002038793.1 2036495 R 512566 CDS YP_002038794.1 194398420 6479828 complement(2037223..2038230) 1 NC_011072.1 identified by match to protein family HMM PF09084; ABC transporter substrate binding protein 2038230 6479828 SPG_2144 Streptococcus pneumoniae G54 ABC transporter substrate binding protein YP_002038794.1 2037223 R 512566 CDS YP_002038795.1 194397949 6480489 complement(2038268..2039017) 1 NC_011072.1 identified by match to protein family HMM PF00528; ABC transporter permease 2039017 6480489 SPG_2145 Streptococcus pneumoniae G54 ABC transporter permease YP_002038795.1 2038268 R 512566 CDS YP_002038796.1 194398058 6479496 complement(2038989..2039279) 1 NC_011072.1 hypothetical protein 2039279 6479496 SPG_2146 Streptococcus pneumoniae G54 hypothetical protein YP_002038796.1 2038989 R 512566 CDS YP_002038797.1 194398386 6478692 complement(2039534..2040832) 1 NC_011072.1 identified by match to protein family HMM PF01473; match to protein family HMM PF05257; match to protein family HMM PF08460; choline binding protein D 2040832 cbpD 6478692 cbpD Streptococcus pneumoniae G54 choline binding protein D YP_002038797.1 2039534 R 512566 CDS YP_002038798.1 194396848 6479219 complement(2040970..2041236) 1 NC_011072.1 identified by match to protein family HMM PF06257; hypothetical protein 2041236 6479219 SPG_2148 Streptococcus pneumoniae G54 hypothetical protein YP_002038798.1 2040970 R 512566 CDS YP_002038799.1 194397193 6478927 complement(2041238..2042590) 1 NC_011072.1 unwinds double stranded DNA; replicative DNA helicase 2042590 dnaB 6478927 dnaB Streptococcus pneumoniae G54 replicative DNA helicase YP_002038799.1 2041238 R 512566 CDS YP_002038800.1 194397284 6480495 complement(2042633..2043085) 1 NC_011072.1 in Escherichia coli this protein is wrapped around the base of the L1 stalk; 50S ribosomal protein L9 2043085 rplI 6480495 rplI Streptococcus pneumoniae G54 50S ribosomal protein L9 YP_002038800.1 2042633 R 512566 CDS YP_002038801.1 194397608 6479366 complement(2043082..2045055) 1 NC_011072.1 identified by match to protein family HMM PF01368; match to protein family HMM PF02272; DHH 1 family protein 2045055 6479366 SPG_2151 Streptococcus pneumoniae G54 DHH 1 family protein YP_002038801.1 2043082 R 512566 CDS YP_002038802.1 194397531 6479042 complement(2045191..2045739) 1 NC_011072.1 identified by match to protein family HMM PF02482; match to protein family HMM TIGR00741; ribosomal subunit interface protein 2045739 yfiA 6479042 yfiA Streptococcus pneumoniae G54 ribosomal subunit interface protein YP_002038802.1 2045191 R 512566 CDS YP_002038803.1 194397008 6479476 complement(2045819..2046481) 1 NC_011072.1 competence protein ComF 2046481 6479476 SPG_2153 Streptococcus pneumoniae G54 competence protein ComF YP_002038803.1 2045819 R 512566 CDS YP_002038804.1 194397929 6479786 complement(2046478..2047776) 1 NC_011072.1 identified by match to protein family HMM PF00271; match to protein family HMM PF04851; helicase 2047776 6479786 SPG_2154 Streptococcus pneumoniae G54 helicase YP_002038804.1 2046478 R 512566 CDS YP_002038805.1 194397335 6479205 2047832..2048467 1 NC_011072.1 identified by match to protein family HMM PF01205; match to protein family HMM PF09186; match to protein family HMM TIGR00257; hypothetical protein 2048467 6479205 SPG_2155 Streptococcus pneumoniae G54 hypothetical protein YP_002038805.1 2047832 D 512566 CDS YP_002038806.1 194397243 6480541 2048752..2049672 1 NC_011072.1 identified by match to protein family HMM PF00291; match to protein family HMM TIGR01136; match to protein family HMM TIGR01139; cysteine synthase 2049672 6480541 SPG_2156 Streptococcus pneumoniae G54 cysteine synthase YP_002038806.1 2048752 D 512566 CDS YP_002038807.1 194396789 6480413 complement(2049869..2050267) 1 NC_011072.1 identified by match to protein family HMM PF03050; IS66-Spn1 transposase 2050267 6480413 SPG_2157 Streptococcus pneumoniae G54 IS66-Spn1 transposase YP_002038807.1 2049869 R 512566 CDS YP_002038808.1 194398702 6479901 2050300..2050545 1 NC_011072.1 IS630-SpnII transposase 2050545 6479901 SPG_2158 Streptococcus pneumoniae G54 IS630-SpnII transposase YP_002038808.1 2050300 D 512566 CDS YP_002038809.1 194397722 6479134 complement(2050686..2051009) 1 NC_011072.1 identified by match to protein family HMM PF05717; IS66-Spn1 transposase 2051009 6479134 SPG_2159 Streptococcus pneumoniae G54 IS66-Spn1 transposase YP_002038809.1 2050686 R 512566 CDS YP_002038810.1 194398126 6480198 complement(2051255..2052295) 1 NC_011072.1 EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu; elongation factor Ts 2052295 tsf 6480198 tsf Streptococcus pneumoniae G54 elongation factor Ts YP_002038810.1 2051255 R 512566 CDS YP_002038811.1 194398612 6480649 complement(2052374..2053153) 1 NC_011072.1 one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit; 30S ribosomal protein S2 2053153 rpsB 6480649 rpsB Streptococcus pneumoniae G54 30S ribosomal protein S2 YP_002038811.1 2052374 R 512566 CDS YP_002038812.1 194398259 6478912 complement(2053377..2054555) 1 NC_011072.1 identified by match to protein family HMM PF05257; CHAP domain-containing protein 2054555 6478912 SPG_2162 Streptococcus pneumoniae G54 CHAP domain-containing protein YP_002038812.1 2053377 R 512566 CDS YP_002038813.1 194397652 6479577 complement(2054649..2055143) 1 NC_011072.1 identified by match to protein family HMM PF04093; match to protein family HMM TIGR03426; cell-shape determining protein MreD 2055143 6479577 SPG_2163 Streptococcus pneumoniae G54 cell-shape determining protein MreD YP_002038813.1 2054649 R 512566 CDS YP_002038814.1 194397343 6478719 complement(2055143..2055961) 1 NC_011072.1 in some organisms this protein is a transmembrane protein while in others it is periplasmic; involved in some organisms with other components of the MreBCD complex and with penicillin binding proteins in the periplasm or cell wall; rod shape-determining protein MreC 2055961 6478719 SPG_2164 Streptococcus pneumoniae G54 rod shape-determining protein MreC YP_002038814.1 2055143 R 512566 CDS YP_002038815.1 194396873 6480436 complement(2056020..2056814) 1 NC_011072.1 identified by match to protein family HMM PF02361; ABC transporter permease 2056814 6480436 SPG_2165 Streptococcus pneumoniae G54 ABC transporter permease YP_002038815.1 2056020 R 512566 CDS YP_002038816.1 194398585 6479326 complement(2056807..2057646) 1 NC_011072.1 with CbiNQ forms the ABC transporter for cobalt import; Streptococcus has two adjacent copies of this gene; cobalt transporter ATP-binding subunit 2057646 cbiO 6479326 cbiO Streptococcus pneumoniae G54 cobalt transporter ATP-binding subunit YP_002038816.1 2056807 R 512566 CDS YP_002038817.1 194398120 6479322 complement(2057631..2058458) 1 NC_011072.1 with CbiNQ forms the ABC transporter for cobalt import; Streptococcus has two adjacent copies of this gene; cobalt transporter ATP-binding subunit 2058458 cbiO 6479322 cbiO Streptococcus pneumoniae G54 cobalt transporter ATP-binding subunit YP_002038817.1 2057631 R 512566 CDS YP_002038818.1 194397810 6479710 complement(2058455..2059000) 1 NC_011072.1 identified by match to protein family HMM PF01066; match to protein family HMM TIGR00560; CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase 2059000 pgsA 6479710 pgsA Streptococcus pneumoniae G54 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase YP_002038818.1 2058455 R 512566 CDS YP_002038819.1 194397048 6480204 complement(2059011..2059832) 1 NC_011072.1 hypothetical protein 2059832 6480204 SPG_2169 Streptococcus pneumoniae G54 hypothetical protein YP_002038819.1 2059011 R 512566 CDS YP_002038820.1 194396898 6479645 complement(2059874..2061157) 1 NC_011072.1 identified by match to protein family HMM PF00675; match to protein family HMM PF05193; M16 family peptidase 2061157 6479645 SPG_2170 Streptococcus pneumoniae G54 M16 family peptidase YP_002038820.1 2059874 R 512566 CDS YP_002038821.1 194396705 6478892 complement(2061154..2062404) 1 NC_011072.1 identified by match to protein family HMM PF05193; M16 family peptidase 2062404 6478892 SPG_2171 Streptococcus pneumoniae G54 M16 family peptidase YP_002038821.1 2061154 R 512566 CDS YP_002038822.1 194398367 6480596 2062563..2062931 1 NC_011072.1 identified by glimmer; putative; hypothetical protein 2062931 6480596 SPG_2172 Streptococcus pneumoniae G54 hypothetical protein YP_002038822.1 2062563 D 512566 CDS YP_002038823.1 194398177 6479600 2062934..2064031 1 NC_011072.1 Required for DNA replication; binds preferentially to single-stranded, linear DNA; recombination protein F 2064031 recF 6479600 recF Streptococcus pneumoniae G54 recombination protein F YP_002038823.1 2062934 D 512566 CDS YP_002038824.1 194397714 6480034 complement(2064082..2065560) 1 NC_011072.1 catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate; inosine 5'-monophosphate dehydrogenase 2065560 6480034 SPG_2174 Streptococcus pneumoniae G54 inosine 5'-monophosphate dehydrogenase YP_002038824.1 2064082 R 512566 CDS YP_002038825.1 194396965 6479968 complement(2065712..2066737) 1 NC_011072.1 catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; tryptophanyl-tRNA synthetase II 2066737 trpS 6479968 trpS Streptococcus pneumoniae G54 tryptophanyl-tRNA synthetase II YP_002038825.1 2065712 R 512566 CDS YP_002038826.1 194397846 6479643 2066943..2068565 1 NC_011072.1 identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 2068565 6479643 SPG_2176 Streptococcus pneumoniae G54 ABC transporter ATP-binding protein YP_002038826.1 2066943 D 512566 CDS YP_002038827.1 194397099 6480441 2068627..2071179 1 NC_011072.1 ABC transporter permease 2071179 6480441 SPG_2177 Streptococcus pneumoniae G54 ABC transporter permease YP_002038827.1 2068627 D 512566 CDS YP_002038828.1 194396658 6480789 complement(2071622..2071960) 1 NC_011072.1 hypothetical protein 2071960 6480789 SPG_2178 Streptococcus pneumoniae G54 hypothetical protein YP_002038828.1 2071622 R 512566 CDS YP_002038829.1 194398321 6479897 complement(2072045..2072812) 1 NC_011072.1 identified by glimmer; putative; hypothetical protein 2072812 6479897 SPG_2179 Streptococcus pneumoniae G54 hypothetical protein YP_002038829.1 2072045 R 512566 CDS YP_002038830.1 194398090 6479035 2072991..2073533 1 NC_011072.1 identified by match to protein family HMM PF00440; hypothetical protein 2073533 6479035 SPG_2180 Streptococcus pneumoniae G54 hypothetical protein YP_002038830.1 2072991 D 512566 CDS YP_002038831.1 194397293 6480616 complement(2073776..2074528) 1 NC_011072.1 identified by match to protein family HMM PF00072; match to protein family HMM PF04397; ComE response regulator TCS12 2074528 comE 6480616 comE Streptococcus pneumoniae G54 ComE response regulator TCS12 YP_002038831.1 2073776 R 512566 CDS YP_002038832.1 194398201 6478696 complement(2074525..2075850) 1 NC_011072.1 identified by match to protein family HMM PF02518; ComD histidine kinase TCS12 2075850 comD 6478696 comD Streptococcus pneumoniae G54 ComD histidine kinase TCS12 YP_002038832.1 2074525 R 512566 CDS YP_002038833.1 194398680 6478779 complement(2075871..2075996) 1 NC_011072.1 identified by match to protein family HMM PF03047; competence-stimulating peptide type 1 2075996 comC 6478779 comC Streptococcus pneumoniae G54 competence-stimulating peptide type 1 YP_002038833.1 2075871 R 512566 CDS YP_002038834.1 194397031 6479584 complement(2076278..2076757) 1 NC_011072.1 SPOUT methyltransferase family protein; crystal structure shows homodimer; in Escherichia coli this protein methylates pseudouridine at position 1915 of the 23S ribosomal RNA; rRNA large subunit methyltransferase 2076757 6479584 SPG_2187 Streptococcus pneumoniae G54 rRNA large subunit methyltransferase YP_002038834.1 2076278 R 512566 CDS YP_002038835.1 194397530 6480135 2076940..2078121 1 NC_011072.1 identified by match to protein family HMM PF00089; serine protease 2078121 6480135 SPG_2188 Streptococcus pneumoniae G54 serine protease YP_002038835.1 2076940 D 512566 CDS YP_002038836.1 194397021 6478723 2078179..2078937 1 NC_011072.1 identified by match to protein family HMM PF02195; match to protein family HMM TIGR00180; ParB-like partition protein 2078937 6478723 SPG_2189 Streptococcus pneumoniae G54 ParB-like partition protein YP_002038836.1 2078179 D 512566 CDS