-- dump date 20140620_084638 -- class Genbank::CDS -- table cds_note -- id note YP_001693435.1 binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication; can also affect transcription of multiple genes including itself. YP_001693436.1 binds the polymerase to DNA and acts as a sliding clamp YP_001693437.1 identified by match to protein family HMM PF06107 YP_001693438.1 translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1 YP_001693439.1 Enables the recycling of peptidyl-tRNAs produced at termination of translation YP_001693440.1 identified by match to protein family HMM PF00270; match to protein family HMM PF00271; match to protein family HMM PF02559; match to protein family HMM PF03461; match to protein family HMM PF04851; match to protein family HMM TIGR00580 YP_001693441.1 identified by match to protein family HMM PF01479 YP_001693442.1 identified by match to protein family HMM PF04977 YP_001693445.1 identified by match to protein family HMM PF01171; match to protein family HMM TIGR02432; match to protein family HMM TIGR02433 YP_001693446.1 identified by match to protein family HMM PF00156; match to protein family HMM TIGR01203 YP_001693447.1 identified by match to protein family HMM PF00004; match to protein family HMM PF01434; match to protein family HMM PF06480; match to protein family HMM TIGR01241 YP_001693450.1 catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis YP_001693451.1 identified by match to protein family HMM PF00589 YP_001693452.1 identified by glimmer YP_001693453.1 identified by match to protein family HMM PF00717; match to protein family HMM PF01381 YP_001693454.1 identified by match to protein family HMM PF01381 YP_001693455.1 identified by glimmer YP_001693458.1 identified by match to protein family HMM PF02498 YP_001693462.1 identified by match to protein family HMM PF04271; match to protein family HMM TIGR01446; match to protein family HMM TIGR01714 YP_001693465.1 identified by glimmer YP_001693467.1 identified by glimmer YP_001693470.1 identified by match to protein family HMM PF00589 YP_001693471.1 identified by match to protein family HMM PF01844 YP_001693473.1 identified by match to protein family HMM PF03354 YP_001693475.1 identified by match to protein family HMM PF04586; match to protein family HMM TIGR01543 YP_001693478.1 identified by match to protein family HMM TIGR01563 YP_001693481.1 identified by match to protein family HMM TIGR01603 YP_001693484.1 identified by match to protein family HMM TIGR01760 YP_001693486.1 identified by match to protein family HMM TIGR01665 YP_001693489.1 identified by match to protein family HMM PF05105; match to protein family HMM TIGR01593 YP_001693490.1 identified by match to protein family HMM TIGR01673 YP_001693491.1 identified by match to protein family HMM PF01473; match to protein family HMM PF01510 YP_001693492.1 identified by glimmer YP_001693493.1 identified by match to protein family HMM PF00383 YP_001693494.1 identified by match to protein family HMM PF00589 YP_001693496.1 identified by match to protein family HMM PF06114 YP_001693497.1 identified by match to protein family HMM PF01381 YP_001693499.1 identified by match to protein family HMM PF03374; match to protein family HMM PF08346 YP_001693503.1 identified by match to protein family HMM PF04404 YP_001693504.1 identified by match to protein family HMM PF07083 YP_001693506.1 identified by match to protein family HMM PF00436; match to protein family HMM TIGR00621 YP_001693507.1 identified by glimmer YP_001693508.1 identified by glimmer YP_001693516.1 identified by match to protein family HMM PF07852 YP_001693519.1 identified by match to protein family HMM PF02195 YP_001693521.1 identified by glimmer YP_001693523.1 identified by match to protein family HMM PF04466; match to protein family HMM PF07570; match to protein family HMM TIGR01547 YP_001693524.1 identified by match to protein family HMM PF05126; match to protein family HMM TIGR01542 YP_001693526.1 identified by match to protein family HMM PF06152 YP_001693527.1 identified by match to protein family HMM PF06810 YP_001693536.1 identified by match to protein family HMM PF06854 YP_001693537.1 identified by match to protein family HMM TIGR02675 YP_001693538.1 identified by match to protein family HMM PF05709; match to protein family HMM TIGR01633 YP_001693539.1 identified by match to protein family HMM TIGR01665 YP_001693540.1 identified by match to protein family HMM PF05895 YP_001693542.1 identified by match to protein family HMM PF05105; match to protein family HMM TIGR01593 YP_001693543.1 identified by match to protein family HMM TIGR01673 YP_001693544.1 catalyzes the formation of dUMP from dUTP YP_001693545.1 identified by match to protein family HMM PF00300 YP_001693546.1 Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents YP_001693547.1 identified by match to protein family HMM PF00484 YP_001693549.1 rppk; phosphoribosylpyrophosphate synthetase; p-rib-pp synthetase; prpp synthetase; catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP YP_001693553.1 has 3'-5' exonuclease, 5'-3' exonuclease and 5'-3'polymerase activities, primarily functions to fill gaps during DNA replication and repair YP_001693554.1 identified by match to protein family HMM PF02629 YP_001693555.1 identified by glimmer YP_001693556.1 identified by match to protein family HMM PF03601 YP_001693557.1 catalyzes the transamination of the aromatic amino acid forming a ketoacid; first step in aromatic amino acid degradation in lactococci YP_001693558.1 involved in DNA repair and RecFOR pathway recombination; RecFOR proteins displace ssDNA-binding protein and facilitate the production of RecA-coated ssDNA YP_001693559.1 involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsY YP_001693562.1 identified by match to protein family HMM TIGR01847 YP_001693563.1 identified by glimmer YP_001693564.1 identified by match to protein family HMM PF01381 YP_001693567.1 identified by glimmer YP_001693568.1 identified by glimmer YP_001693569.1 identified by glimmer YP_001693570.1 identified by match to protein family HMM PF00005; match to protein family HMM PF00664; match to protein family HMM PF03412; match to protein family HMM TIGR01193 YP_001693571.1 identified by match to protein family HMM TIGR01000 YP_001693572.1 catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis; SAICAR synthase YP_001693574.1 identified by match to protein family HMM PF02769; match to protein family HMM TIGR01857 YP_001693575.1 Catalyzes first step of the de novo purine nucleotide biosynthetic pathway YP_001693576.1 catalyzes the formation of 1-(5-phosphoribosyl)-5-aminoimidazole from 2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in purine biosynthesis YP_001693577.1 glycinamide ribonucleotide transformylase; GAR Tfase; catalyzes the synthesis of 5'-phosphoribosylformylglycinamide from 5'-phosphoribosylglycinamide and 10-formyltetrahydrofolate; PurN requires formyl folate for the reaction unlike PurT which uses formate YP_001693578.1 identified by match to protein family HMM PF04892 YP_001693579.1 involved in de novo purine biosynthesis YP_001693580.1 catalyzes the formation of N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-D-ribosylamine and glycine in purine biosynthesis YP_001693582.1 identified by match to protein family HMM PF00731; match to protein family HMM TIGR01162 YP_001693583.1 With PurE catalyzes the conversion of aminoimidazole ribonucleotide to carboxyaminoimidazole ribonucleotide in the de novo purine nucleotide biosynthetic pathway YP_001693585.1 Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide YP_001693586.1 identified by match to protein family HMM PF00728; match to protein family HMM PF00746; match to protein family HMM PF04650; match to protein family HMM PF07501; match to protein family HMM TIGR01167; match to protein family HMM TIGR01168 YP_001693587.1 identified by match to protein family HMM PF00392; match to protein family HMM PF07702 YP_001693588.1 identified by match to protein family HMM PF01301; match to protein family HMM PF02449 YP_001693589.1 identified by match to protein family HMM PF03830 YP_001693590.1 identified by match to protein family HMM PF03609 YP_001693591.1 identified by match to protein family HMM PF03613 YP_001693592.1 identified by match to protein family HMM PF03610 YP_001693593.1 identified by match to protein family HMM PF01380 YP_001693594.1 identified by match to protein family HMM PF01263 YP_001693595.1 identified by match to protein family HMM PF00903 YP_001693596.1 identified by match to protein family HMM PF02583 YP_001693599.1 identified by match to protein family HMM PF01048 YP_001693601.1 identified by match to protein family HMM PF02386 YP_001693602.1 identified by match to protein family HMM PF02254 YP_001693603.1 identified by glimmer YP_001693604.1 identified by match to protein family HMM PF00746; match to protein family HMM PF04650; match to protein family HMM TIGR01167; match to protein family HMM TIGR01168 YP_001693605.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00486 YP_001693606.1 identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518 YP_001693607.1 primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination YP_001693611.1 identified by match to protein family HMM PF00528 YP_001693612.1 identified by match to protein family HMM PF00528 YP_001693613.1 identified by match to protein family HMM PF01547 YP_001693614.1 identified by match to protein family HMM PF00581 YP_001693615.1 identified by glimmer YP_001693619.1 identified by match to protein family HMM PF03551 YP_001693620.1 identified by match to protein family HMM PF07690 YP_001693621.1 identified by match to protein family HMM PF00535 YP_001693622.1 identified by match to protein family HMM PF00106; match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF02719; match to protein family HMM PF04321; match to protein family HMM PF07993 YP_001693623.1 identified by glimmer YP_001693624.1 identified by match to protein family HMM PF00702; match to protein family HMM TIGR01549 YP_001693625.1 identified by match to protein family HMM PF03313; match to protein family HMM TIGR00718 YP_001693626.1 identified by match to protein family HMM PF01842; match to protein family HMM PF03315; match to protein family HMM TIGR00719 YP_001693627.1 identified by match to protein family HMM PF01476 YP_001693628.1 identified by match to protein family HMM PF01381 YP_001693630.1 identified by glimmer YP_001693631.1 identified by match to protein family HMM TIGR01653 YP_001693632.1 identified by match to protein family HMM TIGR01654 YP_001693633.1 identified by match to protein family HMM PF00005 YP_001693634.1 identified by match to protein family HMM PF00497 YP_001693635.1 catalyzes the formation of 2-N(omega)-(L-arginino)succinate from L-citrulline and L-aspartate in arginine biosynthesis, AMP-forming YP_001693636.1 catalyzes the formation of arginine from (N-L-arginino)succinate YP_001693641.1 identified by glimmer YP_001693643.1 identified by glimmer YP_001693650.1 identified by glimmer YP_001693651.1 identified by glimmer YP_001693652.1 identified by match to protein family HMM PF01473 YP_001693653.1 identified by glimmer YP_001693654.1 catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs YP_001693655.1 identified by match to protein family HMM PF00293 YP_001693656.1 GidA; glucose-inhibited cell division protein A; involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U) of the wobble uridine base in some tRNAs YP_001693657.1 identified by match to protein family HMM PF00753; match to protein family HMM PF07521; match to protein family HMM TIGR00649 YP_001693658.1 identified by match to protein family HMM PF07288 YP_001693659.1 identified by glimmer YP_001693660.1 identified by match to protein family HMM TIGR01847 YP_001693662.1 identified by match to protein family HMM PF00814 YP_001693663.1 identified by match to protein family HMM PF00583; match to protein family HMM TIGR01575 YP_001693664.1 in most organisms, only the N-terminal domain is present in a single polypeptide; in some archaea this domain is fused to a kinase domain; this gene is essential for growth in Escherichia coli and Bacillus subtilis; the secreted glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins; the Pyrococcus structure shows DNA-binding properties, iron-binding, ATP-binding, and AP endonuclease activity YP_001693666.1 identified by match to protein family HMM PF00534 YP_001693667.1 identified by match to protein family HMM PF00535 YP_001693668.1 identified by match to protein family HMM PF00005 YP_001693669.1 identified by glimmer YP_001693670.1 identified by match to protein family HMM PF00984; match to protein family HMM PF03721; match to protein family HMM TIGR03026 YP_001693671.1 identified by match to protein family HMM TIGR01716 YP_001693672.1 identified by glimmer YP_001693673.1 identified by match to protein family HMM PF02517 YP_001693674.1 identified by match to protein family HMM PF07690 YP_001693675.1 identified by glimmer YP_001693676.1 identified by match to protein family HMM PF03591 YP_001693677.1 identified by match to protein family HMM PF05437 YP_001693678.1 identified by match to protein family HMM PF00497 YP_001693679.1 identified by match to protein family HMM PF03180 YP_001693680.1 identified by match to protein family HMM PF01546; match to protein family HMM PF07687 YP_001693681.1 identified by match to protein family HMM PF00005 YP_001693682.1 identified by match to protein family HMM PF00528 YP_001693683.1 identified by match to protein family HMM TIGR02185 YP_001693684.1 identified by match to protein family HMM PF04854 YP_001693685.1 identified by match to protein family HMM PF00672; match to protein family HMM PF02518; match to protein family HMM PF06580 YP_001693686.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00165 YP_001693688.1 has a stimulatory effect on the ribonucleotide reductase activity of NrdH with NrdEF YP_001693690.1 identified by match to protein family HMM PF01609 YP_001693693.1 identified by match to protein family HMM PF04397 YP_001693694.1 identified by glimmer YP_001693695.1 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. Promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex YP_001693696.1 RibE; 6,7-diimethyl-8-ribityllumazine synthase; DMRL synthase; lumazine synthase; beta subunit of riboflavin synthase; condenses 5-amino-6-(1'-D)-ribityl-amino-2,4(1H,3H)-pyrimidinedione with L-3,4-dihydrohy-2-butanone-4-phosphate to generate 6,6-dimethyl-8-lumazine (DMRL); riboflavin synthase then uses 2 molecules of DMRL to produce riboflavin (vitamin B12); involved in the last steps of riboflavin biosynthesis; forms a 60mer (icosahedral shell) in both Bacillus subtilis and Escherichia coli; in Bacillus subtilis this 60mer is associated with the riboflavin synthase subunit (alpha) while in Escherichia coli it is not YP_001693697.1 identified by match to protein family HMM PF00925; match to protein family HMM PF00926; match to protein family HMM TIGR00505; match to protein family HMM TIGR00506 YP_001693698.1 catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine YP_001693699.1 identified by match to protein family HMM PF00383; match to protein family HMM PF01872; match to protein family HMM TIGR00227; match to protein family HMM TIGR00326 YP_001693700.1 plays an essential role in ATP-dependent branch migration of the Holliday junction YP_001693701.1 identified by match to protein family HMM PF03352 YP_001693702.1 identified by match to protein family HMM PF02517 YP_001693703.1 identified by match to protein family HMM PF02016 YP_001693705.1 identified by match to protein family HMM PF06570 YP_001693706.1 identified by match to protein family HMM PF01544 YP_001693707.1 identified by match to protein family HMM PF00589 YP_001693708.1 identified by match to protein family HMM PF04326 YP_001693709.1 identified by match to protein family HMM PF01381 YP_001693717.1 identified by match to protein family HMM PF08708 YP_001693718.1 identified by match to protein family HMM PF08706; match to protein family HMM TIGR01613 YP_001693719.1 identified by glimmer YP_001693722.1 identified by match to protein family HMM PF08281 YP_001693723.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate YP_001693724.1 identified by match to protein family HMM PF00557; match to protein family HMM PF01321 YP_001693725.1 the anti-alpha factor Spx interacts with RNA polymerase alpha subunit C-terminal domain in a region that interacts with the sigma 70 subunit and may interfere with activation of promoters; in Bacillus subtilis this protein is a substrate for ClpXP protease; blocks transcription of the competence regulatory gene encoded by the srf operon; regulates a number of genes involved in thiol homeostasis including trxA and trxB; monomeric member of ArsC family of proteins; does not bind DNA; contains a disulfide bond between C10 and C13 which may sense disulfide stress YP_001693727.1 identified by match to protein family HMM PF06135 YP_001693728.1 similar to RuvC resolvase with substantial differences; NMR structural information suggests this protein is monomeric; unknown cellular function YP_001693729.1 identified by match to protein family HMM PF06949 YP_001693730.1 identified by glimmer YP_001693731.1 identified by match to protein family HMM PF02875; match to protein family HMM PF08245; match to protein family HMM TIGR01499 YP_001693733.1 identified by match to protein family HMM PF00614 YP_001693735.1 Catalyzes the reduction of nucleoside 5'-triphosphates to 2'-deoxynucleoside 5'-triphosphates YP_001693737.1 identified by match to protein family HMM PF00583 YP_001693738.1 identified by match to protein family HMM PF04055; match to protein family HMM TIGR02491 YP_001693739.1 identified by match to protein family HMM PF00485 YP_001693740.1 NusE; involved in assembly of the 30S subunit; in the ribosome, this protein is involved in the binding of tRNA; in Escherichia coli this protein was also found to be involved in transcription antitermination; NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination; binding of NusB/S10 to boxA nucleates assembly of the antitermination complex YP_001693741.1 binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin YP_001693742.1 L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA YP_001693743.1 binds third domain of 23S rRNA and protein L29; part of exit tunnel YP_001693744.1 one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation YP_001693745.1 protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA YP_001693746.1 binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center YP_001693747.1 forms a complex with S10 and S14; binds the lower part of the 30S subunit head and the mRNA in the complete ribosome to position it for translation YP_001693748.1 located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e YP_001693749.1 one of the stabilizing components for the large ribosomal subunit YP_001693750.1 primary binding protein; helps mediate assembly; involved in translation fidelity YP_001693751.1 binds to the 23S rRNA between the centers for peptidyl transferase and GTPase YP_001693752.1 assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel YP_001693753.1 part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13 YP_001693754.1 located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group do not appear to have the zinc-binding motif YP_001693755.1 binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit YP_001693756.1 ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance YP_001693757.1 binds 5S rRNA along with protein L5 and L25 YP_001693758.1 located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance YP_001693759.1 L30 binds domain II of the 23S rRNA and the 5S rRNA; similar to eukaryotic protein L7 YP_001693760.1 late assembly protein YP_001693761.1 forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase YP_001693762.1 ATP-AMP transphosphorylase; AK; Superoxide-inducible protein 16; SOI16; essential enzyme that recycles AMP in active cells; converts ATP and AMP to two molecules of ADP YP_001693763.1 stimulates the activities of the other two initiation factors, IF-2 and IF-3 YP_001693764.1 smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group have the motif YP_001693765.1 located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA YP_001693766.1 located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3 YP_001693767.1 catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme YP_001693768.1 is a component of the macrolide binding site in the peptidyl transferase center YP_001693769.1 ACT domain-containing protein YP_001693770.1 identified by match to protein family HMM PF05167 YP_001693771.1 identified by match to protein family HMM PF00300 YP_001693772.1 identified by match to protein family HMM PF00005; match to protein family HMM PF08402 YP_001693774.1 identified by match to protein family HMM PF04055; match to protein family HMM TIGR02494 YP_001693775.1 identified by match to protein family HMM PF00455; match to protein family HMM PF08220; match to protein family HMM PF08279 YP_001693776.1 identified by match to protein family HMM PF04198 YP_001693777.1 identified by match to protein family HMM PF02255 YP_001693778.1 identified by match to protein family HMM PF02302 YP_001693779.1 pts system lichenan-specific eiiccomponent; eiic-lic; identified by match to protein family HMM PF02378; match to protein family HMM TIGR00410 YP_001693780.1 identified by match to protein family HMM PF01228; match to protein family HMM PF02901; match to protein family HMM TIGR01774 YP_001693781.1 similar to transaldolase from Escherichia coli; many organisms have multiple copies YP_001693782.1 forms dimers and octamers; involved in conversion of glycerol to dihydroxy-acetone YP_001693783.1 leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase YP_001693784.1 identified by glimmer YP_001693785.1 identified by match to protein family HMM PF00583 YP_001693786.1 identified by match to protein family HMM PF00583 YP_001693787.1 promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration YP_001693788.1 identified by match to protein family HMM PF06042 YP_001693789.1 catalyzes the formation of undecaprenyl pyrophosphate from isopentenyl pyrophosphate YP_001693790.1 identified by match to protein family HMM PF01148 YP_001693791.1 identified by match to protein family HMM PF02163; match to protein family HMM TIGR00054 YP_001693792.1 catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro) YP_001693793.1 identified by match to protein family HMM PF00232 YP_001693794.1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source YP_001693796.1 identified by match to protein family HMM PF00296 YP_001693797.1 identified by match to protein family HMM PF00128; match to protein family HMM PF00746; match to protein family HMM PF02922; match to protein family HMM PF03714; match to protein family HMM PF04650; match to protein family HMM TIGR01167; match to protein family HMM TIGR01168; match to protein family HMM TIGR02102 YP_001693798.1 interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance YP_001693799.1 binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit YP_001693800.1 EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene YP_001693801.1 catalyzes DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time; required for leading strand synthesis; PolC exhibits 3' to 5' exonuclease activity YP_001693802.1 identified by match to protein family HMM PF04221; match to protein family HMM TIGR02384 YP_001693803.1 identified by match to protein family HMM PF05016; match to protein family HMM TIGR02385 YP_001693805.1 identified by match to protein family HMM PF02073 YP_001693806.1 identified by match to protein family HMM PF01844 YP_001693807.1 identified by match to protein family HMM PF00849; match to protein family HMM PF01479; match to protein family HMM TIGR00093 YP_001693808.1 identified by match to protein family HMM PF03051 YP_001693809.1 identified by match to protein family HMM PF03613; match to protein family HMM TIGR00828 YP_001693810.1 identified by match to protein family HMM PF03609 YP_001693811.1 identified by match to protein family HMM PF03610; match to protein family HMM PF03830 YP_001693812.1 similar to zinc-dependent eukaryotic ADH enzymes and distinct from fermentative ADHs YP_001693813.1 identified by match to protein family HMM PF00702; match to protein family HMM PF05116; match to protein family HMM PF08282; match to protein family HMM TIGR00099; match to protein family HMM TIGR01484 YP_001693814.1 identified by match to protein family HMM PF00860 YP_001693815.1 identified by match to protein family HMM PF02517 YP_001693816.1 identified by glimmer YP_001693817.1 identified by match to protein family HMM PF00809; match to protein family HMM TIGR01496 YP_001693818.1 identified by match to protein family HMM PF02875; match to protein family HMM PF08245; match to protein family HMM TIGR01499 YP_001693819.1 involved in the first step of tetrahydrofolate biosynthesis; catalyzes the formation of formate and 2-amino-4-hydroxy-6-(erythro-1,2, 3-trihydroxypropyl)dihydropteridine triphosphate from GTP and water; forms a homopolymer YP_001693820.1 identified by match to protein family HMM PF01288; match to protein family HMM PF02152; match to protein family HMM TIGR00525; match to protein family HMM TIGR00526; match to protein family HMM TIGR01498 YP_001693822.1 in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit YP_001693823.1 forms a direct contact with the tRNA during translation YP_001693824.1 identified by match to protein family HMM PF00589 YP_001693825.1 identified by glimmer YP_001693827.1 identified by glimmer YP_001693829.1 identified by glimmer YP_001693833.1 identified by glimmer YP_001693835.1 identified by match to protein family HMM PF01055 YP_001693836.1 hydrogen peroxide resistanceprotein 1; oxidant receptor peroxidase 1; glutathione peroxidase 3; phospholipid hydroperoxide glutathione peroxidase 3; phgpx3; identified by match to protein family HMM PF00255 YP_001693837.1 identified by match to protein family HMM PF00746; match to protein family HMM PF02018; match to protein family HMM PF02278; match to protein family HMM PF02884; match to protein family HMM PF08124; match to protein family HMM TIGR01167 YP_001693838.1 catalyzes the formation of pyruvate and glyoxylate from 4-hydroxy-2-oxoglutarate; or pyruvate and D-glyceraldehyde 3-phosphate from 2-dehydro-3-deoxy-D-glyconate 6-phosphate YP_001693839.1 identified by match to protein family HMM PF00294 YP_001693840.1 identified by match to protein family HMM PF02502 YP_001693841.1 Involved in the nonphosphorylative, ketogenic oxidation of glucose and oxidizes gluconate to 5-ketogluconate YP_001693842.1 identified by match to protein family HMM PF03610 YP_001693843.1 UGL; Glycuronidase; Unsaturated uronic acid hydrolase; Glycosaminoglycan hydrolase; identified by match to protein family HMM PF07470 YP_001693844.1 pts system n-acetylgalactosamine-specific eiib component 2; eiib-aga'; identified by match to protein family HMM PF03830 YP_001693845.1 identified by match to protein family HMM PF03609 YP_001693846.1 identified by match to protein family HMM PF03613 YP_001693847.1 identified by match to protein family HMM PF02699; match to protein family HMM TIGR00739 YP_001693848.1 identified by match to protein family HMM PF07940 YP_001693849.1 identified by match to protein family HMM PF00356; match to protein family HMM PF00532 YP_001693850.1 identified by glimmer YP_001693851.1 identified by glimmer YP_001693853.1 identified by match to protein family HMM PF01381 YP_001693854.1 identified by match to protein family HMM PF01795; match to protein family HMM TIGR00006 YP_001693855.1 identified by match to protein family HMM TIGR02209 YP_001693856.1 identified by match to protein family HMM PF00905; match to protein family HMM PF03717; match to protein family HMM PF03793 YP_001693857.1 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan YP_001693858.1 identified by glimmer YP_001693859.1 identified by match to protein family HMM PF00004; match to protein family HMM PF07724; match to protein family HMM PF07728 YP_001693860.1 catalyzes the hydrolysis of S-ribosylhomocysteine to homocysteine and autoinducer-2 YP_001693861.1 identified by match to protein family HMM PF08903 YP_001693862.1 identified by match to protein family HMM PF00128 YP_001693864.1 identified by match to protein family HMM PF01710 YP_001693865.1 identified by match to protein family HMM PF02916; match to protein family HMM PF03816; match to protein family HMM TIGR00350 YP_001693866.1 identified by match to protein family HMM PF02811 YP_001693867.1 identified by match to protein family HMM PF02706; match to protein family HMM TIGR01006 YP_001693868.1 identified by match to protein family HMM TIGR01007 YP_001693869.1 identified by match to protein family HMM PF02397; match to protein family HMM TIGR03025 YP_001693870.1 identified by match to protein family HMM PF03808; match to protein family HMM TIGR00696 YP_001693871.1 identified by match to protein family HMM PF04991 YP_001693872.1 identified by match to protein family HMM PF00535 YP_001693874.1 identified by match to protein family HMM PF01943 YP_001693875.1 identified by match to protein family HMM PF02350; match to protein family HMM TIGR00236 YP_001693876.1 identified by match to protein family HMM PF00483; match to protein family HMM TIGR01207 YP_001693877.1 identified by match to protein family HMM PF00908 YP_001693878.1 identified by match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF02719; match to protein family HMM PF04321; match to protein family HMM PF07993; match to protein family HMM TIGR01181 YP_001693879.1 identified by match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF02719; match to protein family HMM PF04321; match to protein family HMM PF07993; match to protein family HMM TIGR01214 YP_001693880.1 identified by match to protein family HMM PF00496 YP_001693881.1 identified by match to protein family HMM PF00754; match to protein family HMM TIGR01167 YP_001693882.1 identified by match to protein family HMM PF00905; match to protein family HMM PF00912; match to protein family HMM TIGR02074 YP_001693883.1 functions in homologous recombination, DNA repair, and chromosome segregation; binds preferentially to three- and four-stranded DNA intermediates; introduces specific nick sites in four-stranded DNA substrates; functions similarly to Escherichia coli RuvC YP_001693884.1 identified by match to protein family HMM PF06908 YP_001693885.1 identified by match to protein family HMM PF05103 YP_001693886.1 identified by match to protein family HMM PF01170 YP_001693888.1 catalyzes the formation of D-ribulose 5-phosphate from 6-phospho-D-gluconate YP_001693889.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00486 YP_001693890.1 identified by match to protein family HMM PF01473 YP_001693891.1 identified by match to protein family HMM PF07690 YP_001693892.1 identified by match to protein family HMM PF01473 YP_001693893.1 identified by match to protein family HMM PF00288; match to protein family HMM PF08544; match to protein family HMM TIGR00549 YP_001693894.1 identified by match to protein family HMM PF00288; match to protein family HMM PF08544; match to protein family HMM TIGR01240 YP_001693895.1 identified by match to protein family HMM PF00288; match to protein family HMM PF08544; match to protein family HMM TIGR01220 YP_001693896.1 catalyzes the isomerization of isopentenyl pyrophosphate to dimethylallyl diphosphate YP_001693898.1 identified by match to protein family HMM PF02518; match to protein family HMM PF07730 YP_001693899.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00196; match to protein family HMM PF08281 YP_001693901.1 identified by match to protein family HMM PF01473 YP_001693902.1 identified by match to protein family HMM PF00665 YP_001693903.1 identified by match to protein family HMM PF02302; match to protein family HMM PF02378; match to protein family HMM TIGR00851 YP_001693904.1 identified by match to protein family HMM PF08279 YP_001693905.1 pts system mannitol-specific eiia component; eiia-mtl; eiii-mtl; identified by match to protein family HMM PF00359 YP_001693906.1 identified by match to protein family HMM PF01232; match to protein family HMM PF08125 YP_001693908.1 Tig; RopA; peptidyl-prolyl cis/trans isomerase; promotes folding of newly synthesized proteins; binds ribosomal 50S subunit; forms a homodimer YP_001693909.1 identified by match to protein family HMM TIGR01448 YP_001693910.1 identified by match to protein family HMM PF00717; match to protein family HMM TIGR02227 YP_001693911.1 An endonuclease that specifically degrades the RNA strand of RNA-DNA hybrids YP_001693913.1 identified by match to protein family HMM PF02674 YP_001693914.1 identified by match to protein family HMM PF00488; match to protein family HMM PF01713; match to protein family HMM TIGR01069 YP_001693915.1 identified by match to protein family HMM PF01235; match to protein family HMM TIGR00835 YP_001693916.1 identified by match to protein family HMM PF02627; match to protein family HMM TIGR00778 YP_001693917.1 identified by match to protein family HMM PF03595 YP_001693918.1 catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_001693919.1 identified by match to protein family HMM PF06115 YP_001693920.1 catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP; lysine and threonine sensitive YP_001693922.1 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA YP_001693923.1 identified by match to protein family HMM PF01047; match to protein family HMM PF03965 YP_001693924.1 FabH; beta-ketoacyl-acyl carrier protein synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs YP_001693925.1 carries the fatty acid chain in fatty acid biosynthesis YP_001693926.1 identified by match to protein family HMM PF03060; match to protein family HMM TIGR03151 YP_001693927.1 identified by match to protein family HMM PF00698; match to protein family HMM TIGR00128 YP_001693928.1 catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis YP_001693929.1 FabF; beta-ketoacyl-ACP synthase II, KASII; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP YP_001693930.1 composes the biotin carboxyl carrier protein subunit of the acetyl-CoA carboxylase complex, the enzyme that catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, which in turn controls the rate of fatty acid metabolism YP_001693931.1 in Pseudomonas aeruginosa this enzyme is a trimer of dimers; essential for membrane formation; performs third step of type II fatty acid biosynthesis; catalyzes dehydration of (3R)-hydroxyacyl-ACP to trans-2-acyl-ACP YP_001693932.1 an AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism YP_001693933.1 catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer of AccA2D2 subunits YP_001693934.1 catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer composed of two alpha (AccA) and two beta (AccD) subunits; one of the two catalytic subunits that can form the acetyl CoA carboxylase enzyme together with a carrier protein; these proteins present a shorter N-terminus YP_001693937.1 Regulates rRNA biosynthesis by transcriptional antitermination YP_001693938.1 identified by match to protein family HMM PF03780 YP_001693939.1 Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA YP_001693940.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA YP_001693941.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA YP_001693942.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; some Mycoplasma proteins contain an N-terminal fusion to an unknown domain YP_001693943.1 stimulates the release of release factors 1 and 2 from the ribosome after hydrolysis of the ester bond in peptidyl-tRNA has occurred; GDP/GTP-binding protein YP_001693944.1 required for 70S ribosome assembly YP_001693945.1 identified by match to protein family HMM PF03780 YP_001693946.1 identified by match to protein family HMM PF02734 YP_001693947.1 catalyzes the formation of 2-acetolactate from pyruvate; also known as acetolactate synthase large subunit YP_001693948.1 with IlvI catalyzes the formation of 2-acetolactate from pyruvate, the small subunit is required for full activity and valine sensitivity; E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates, valine sensitivity and affinity for cofactors; also known as acetolactate synthase 3 small subunit YP_001693949.1 catalyzes the formation of (R)-2,3-dihydroxy-3-methylbutanoate from (S)-2-hydroxy-2-methyl-3-oxobutanoate in valine and isoleucine biosynthesis YP_001693952.1 catalyzes the formation of 2-oxobutanoate from L-threonine; biosynthetic YP_001693955.1 identified by match to protein family HMM PF00005 YP_001693956.1 identified by match to protein family HMM PF00497; match to protein family HMM PF00528; match to protein family HMM TIGR01726 YP_001693959.1 Undecaprenyl pyrophosphatephosphatase; Bacitracin resistance protein; BacA; phosphatase activity in Escherichia coli not kinase; involved in bacitracin resistance as bacitracin supposedly sequesters undecaprenyl disphosphate which reduces the pool of lipid carrier available to the cell YP_001693961.1 involved in translesion DNA polymerization with beta clamp of polymerase III; belongs to Y family of polymerases; does not contain proofreading function YP_001693962.1 identified by glimmer YP_001693963.1 identified by match to protein family HMM PF01228; match to protein family HMM PF02901; match to protein family HMM TIGR01255 YP_001693964.1 identified by match to protein family HMM PF01610 YP_001693965.1 identified by match to protein family HMM PF05043; match to protein family HMM PF08270; match to protein family HMM PF08280 YP_001693966.1 identified by match to protein family HMM PF00092; match to protein family HMM PF05738; match to protein family HMM TIGR01167 YP_001693967.1 identified by match to protein family HMM PF00746; match to protein family HMM PF05738; match to protein family HMM TIGR01167 YP_001693968.1 identified by glimmer YP_001693969.1 identified by match to protein family HMM PF05738; match to protein family HMM TIGR01167 YP_001693970.1 identified by match to protein family HMM PF04203; match to protein family HMM TIGR01076 YP_001693971.1 identified by match to protein family HMM PF04203; match to protein family HMM TIGR01076 YP_001693972.1 identified by match to protein family HMM PF04203; match to protein family HMM TIGR01076 YP_001693975.1 identified by glimmer YP_001693976.1 identified by match to protein family HMM PF00480 YP_001693977.1 pts system lichenan-specific eiiccomponent; eiic-lic; identified by match to protein family HMM PF02378; match to protein family HMM TIGR00410 YP_001693979.1 pts system lactose-specific eiia component; eiia-lac; eiii-lac; identified by match to protein family HMM PF02255 YP_001693980.1 catalyzes the formation of 6-phospho-galactose from a 6-phospho-beta-galactoside YP_001693981.1 identified by match to protein family HMM PF02302; match to protein family HMM PF02378 YP_001693982.1 identified by match to protein family HMM PF02386 YP_001693983.1 involved in potassium uptake; found to be peripherally associated with the inner membrane in Escherichia coli; contains an NAD-binding domain YP_001693984.1 identified by match to protein family HMM PF01887 YP_001693985.1 identified by match to protein family HMM PF07155 YP_001693987.1 identified by match to protein family HMM PF00005 YP_001693988.1 identified by match to protein family HMM PF02361 YP_001693989.1 identified by match to protein family HMM PF00588 YP_001693991.1 identified by match to protein family HMM PF01569 YP_001693994.1 participates in both the initiation and recycling phases of transcription; in the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling YP_001693995.1 identified by glimmer YP_001693996.1 CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer YP_001693997.1 identified by match to protein family HMM PF01895; match to protein family HMM PF02690; match to protein family HMM TIGR00704 YP_001693998.1 identified by match to protein family HMM PF00746; match to protein family HMM PF00754; match to protein family HMM PF03644; match to protein family HMM PF04650; match to protein family HMM PF07501; match to protein family HMM PF07523; match to protein family HMM TIGR01167; match to protein family HMM TIGR01168 YP_001693999.1 Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway YP_001694001.1 identified by match to protein family HMM PF00376 YP_001694002.1 identified by match to protein family HMM PF00120; match to protein family HMM PF03951; match to protein family HMM TIGR00653 YP_001694005.1 identified by match to protein family HMM PF01420 YP_001694006.1 identified by match to protein family HMM PF00589 YP_001694007.1 identified by match to protein family HMM PF01420 YP_001694008.1 identified by match to protein family HMM PF01420 YP_001694009.1 identified by match to protein family HMM PF02384; match to protein family HMM PF05175 YP_001694010.1 identified by match to protein family HMM PF00270; match to protein family HMM PF04313; match to protein family HMM PF04851; match to protein family HMM PF08463 YP_001694012.1 identified by glimmer YP_001694013.1 Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons YP_001694014.1 with DnaK and DnaJ acts in response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins; may act as a thermosensor YP_001694015.1 heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria YP_001694016.1 chaperone Hsp40; co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion YP_001694018.1 identified by match to protein family HMM PF01230 YP_001694019.1 identified by match to protein family HMM PF00005 YP_001694020.1 identified by match to protein family HMM PF05975 YP_001694022.1 identified by match to protein family HMM PF04397 YP_001694023.1 identified by match to protein family HMM PF00072; match to protein family HMM PF04397 YP_001694024.1 identified by match to protein family HMM PF02518 YP_001694025.1 identified by match to protein family HMM PF08128; match to protein family HMM TIGR01847 YP_001694026.1 identified by match to protein family HMM TIGR01000 YP_001694027.1 identified by match to protein family HMM PF00005; match to protein family HMM PF00664; match to protein family HMM PF03412; match to protein family HMM TIGR01193 YP_001694029.1 identified by match to protein family HMM TIGR01847 YP_001694030.1 identified by match to protein family HMM TIGR01847 YP_001694031.1 identified by glimmer YP_001694033.1 identified by glimmer YP_001694034.1 identified by glimmer YP_001694035.1 identified by match to protein family HMM PF02517 YP_001694036.1 identified by match to protein family HMM PF02517 YP_001694037.1 identified by match to protein family HMM PF01636 YP_001694038.1 tRNA (guanine-N(7)-)-methyltransferase; catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA by transferring the methyl residue from S-adenosyl-L-methionine YP_001694039.1 in Streptococcus pneumoniae this gene was found to be essential; structure determination of the Streptococcus protein shows that it is similar to a number of other proteins YP_001694040.1 modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination YP_001694041.1 identified by match to protein family HMM PF04296 YP_001694042.1 identified by match to protein family HMM PF01248 YP_001694043.1 Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex YP_001694044.1 associates with free 30S ribosomal subunits; essential for efficient processing of 16S rRNA; in Escherichia coli rbfA is induced by cold shock YP_001694048.1 identified by glimmer YP_001694049.1 identified by match to protein family HMM PF08984 YP_001694050.1 identified by match to protein family HMM PF01814; match to protein family HMM PF04282; match to protein family HMM TIGR00229 YP_001694051.1 identified by match to protein family HMM PF08930 YP_001694053.1 identified by glimmer YP_001694054.1 identified by match to protein family HMM PF00583 YP_001694056.1 valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain YP_001694058.1 identified by glimmer YP_001694059.1 identified by glimmer YP_001694060.1 identified by match to protein family HMM PF02661 YP_001694061.1 identified by match to protein family HMM PF00874; match to protein family HMM PF03123 YP_001694062.1 identified by match to protein family HMM PF00358; match to protein family HMM PF00367; match to protein family HMM PF02378; match to protein family HMM TIGR00830; match to protein family HMM TIGR01995 YP_001694063.1 Gentiobiase; Cellobiase; Beta-D-glucoside glucohydrolase; Amygdalase; identified by match to protein family HMM PF00232 YP_001694064.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily YP_001694065.1 identified by match to protein family HMM PF00583 YP_001694066.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily YP_001694067.1 identified by match to protein family HMM PF03372 YP_001694069.1 identified by match to protein family HMM PF01381 YP_001694070.1 catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine to form methionine YP_001694071.1 identified by match to protein family HMM PF02219; match to protein family HMM TIGR00676 YP_001694072.1 identified by match to protein family HMM PF00013; match to protein family HMM PF00575; match to protein family HMM PF01138; match to protein family HMM PF03725; match to protein family HMM PF03726 YP_001694073.1 identified by match to protein family HMM TIGR01172 YP_001694074.1 identified by match to protein family HMM PF00583 YP_001694075.1 catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA YP_001694076.1 identified by match to protein family HMM PF00636 YP_001694078.1 identified by glimmer YP_001694079.1 identified by match to protein family HMM PF02687 YP_001694080.1 identified by match to protein family HMM PF00005 YP_001694081.1 identified by match to protein family HMM PF02687 YP_001694082.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00486 YP_001694083.1 identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518 YP_001694084.1 catalyzes the formation of glycerone phosphate and glyceraldehyde 3-phosphate from fructose 1,6, bisphosphate YP_001694085.1 identified by match to protein family HMM PF00175; match to protein family HMM PF00970; match to protein family HMM PF01794 YP_001694086.1 identified by match to protein family HMM PF00528; match to protein family HMM TIGR01726 YP_001694087.1 identified by match to protein family HMM PF00528; match to protein family HMM TIGR01726 YP_001694088.1 identified by match to protein family HMM PF00497 YP_001694089.1 identified by match to protein family HMM PF00005 YP_001694090.1 identified by match to protein family HMM PF01368; match to protein family HMM PF02272; match to protein family HMM TIGR00644 YP_001694091.1 identified by match to protein family HMM PF00753; match to protein family HMM PF07521 YP_001694092.1 identified by match to protein family HMM PF00756 YP_001694093.1 identified by match to protein family HMM PF02388 YP_001694094.1 identified by match to protein family HMM PF02388 YP_001694095.1 identified by match to protein family HMM PF00413 YP_001694096.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision YP_001694097.1 identified by match to protein family HMM PF00149 YP_001694098.1 identified by match to protein family HMM PF00497 YP_001694099.1 identified by match to protein family HMM PF00881 YP_001694100.1 divalent metal ion-dependent extracellular dipeptidase; able to hydrolyze a broad range of dipeptides but no tri-, tetra-, or larger oligopeptides; differences in the amino acid specificity of the cleavage site varies between species; similar to succinyl-diaminopimelate desuccinylases YP_001694101.1 identified by match to protein family HMM PF03167 YP_001694102.1 identified by glimmer YP_001694103.1 identified by glimmer YP_001694104.1 identified by match to protein family HMM PF05525; match to protein family HMM TIGR00796 YP_001694105.1 identified by match to protein family HMM PF05343 YP_001694106.1 identified by match to protein family HMM PF01230 YP_001694107.1 identified by match to protein family HMM PF02557 YP_001694108.1 binds directly to 23S ribosomal RNA YP_001694109.1 in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA YP_001694112.1 identified by match to protein family HMM PF00005 YP_001694113.1 identified by match to protein family HMM PF06182 YP_001694114.1 identified by match to protein family HMM PF06182 YP_001694115.1 identified by glimmer YP_001694116.1 identified by glimmer YP_001694118.1 identified by match to protein family HMM PF00082; match to protein family HMM PF00746; match to protein family HMM PF02225; match to protein family HMM PF05922; match to protein family HMM PF06280; match to protein family HMM TIGR01167 YP_001694120.1 identified by match to protein family HMM PF00359 YP_001694122.1 identified by match to protein family HMM PF03611 YP_001694123.1 identified by match to protein family HMM PF00703; match to protein family HMM PF00746; match to protein family HMM PF02836; match to protein family HMM PF02837; match to protein family HMM PF04650; match to protein family HMM PF07501; match to protein family HMM PF07532; match to protein family HMM TIGR01167; match to protein family HMM TIGR01168 YP_001694124.1 identified by glimmer YP_001694125.1 identified by glimmer YP_001694126.1 identified by glimmer YP_001694128.1 identified by match to protein family HMM PF06962 YP_001694130.1 identified by match to protein family HMM PF03631 YP_001694131.1 identified by match to protein family HMM PF02683 YP_001694132.1 identified by match to protein family HMM PF00578; match to protein family HMM PF08534 YP_001694133.1 identified by match to protein family HMM PF01625; match to protein family HMM PF01641; match to protein family HMM TIGR00357; match to protein family HMM TIGR00401 YP_001694134.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00165 YP_001694135.1 identified by match to protein family HMM PF00672; match to protein family HMM PF02518; match to protein family HMM PF02743; match to protein family HMM PF06580 YP_001694136.1 identified by match to protein family HMM PF04260; match to protein family HMM TIGR01440 YP_001694137.1 identified by match to protein family HMM PF00746; match to protein family HMM PF05342; match to protein family HMM PF07501; match to protein family HMM PF07580; match to protein family HMM TIGR01167 YP_001694138.1 identified by match to protein family HMM PF00425; match to protein family HMM TIGR00553 YP_001694140.1 identified by match to protein family HMM PF01473; match to protein family HMM PF05901 YP_001694141.1 identified by match to protein family HMM PF00480; match to protein family HMM TIGR00744 YP_001694142.1 ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived YP_001694144.1 IPP transferase; isopentenyltransferase; involved in tRNA modification; in Escherichia coli this enzyme catalyzes the addition of a delta2-isopentenyl group from dimethylallyl diphosphate to the N6-nitrogen of adenosine adjacent to the anticodon of tRNA species that read codons starting with uracil; further tRNA modifications may occur; mutations in miaA result in defects in translation efficiency and fidelity YP_001694145.1 identified by match to protein family HMM PF01926; match to protein family HMM TIGR00231; match to protein family HMM TIGR03156 YP_001694147.1 member of metallo-beta-lactamase; the purified enzyme from Escherichia coli forms dimeric zinc phosphodiesterase; in Bacillus subtilis this protein is a 3'-tRNA processing endoribonuclease and is essential while in Escherichia coli it is not; associates with two zinc ions YP_001694148.1 identified by match to protein family HMM PF00106; match to protein family HMM PF08659 YP_001694149.1 identified by match to protein family HMM PF00126 YP_001694150.1 identified by match to protein family HMM PF06014 YP_001694151.1 identified by match to protein family HMM PF00581 YP_001694153.1 identified by match to protein family HMM PF00849; match to protein family HMM PF01479; match to protein family HMM TIGR00093 YP_001694154.1 identified by match to protein family HMM PF00009; match to protein family HMM PF00679; match to protein family HMM PF03144; match to protein family HMM TIGR00231; match to protein family HMM TIGR01394 YP_001694156.1 identified by match to protein family HMM TIGR01653 YP_001694157.1 identified by match to protein family HMM PF00005 YP_001694158.1 UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation YP_001694159.1 UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; involved in cell wall formation; inner membrane-associated; last step of peptidoglycan synthesis YP_001694160.1 identified by match to protein family HMM PF03799; match to protein family HMM PF08478 YP_001694161.1 type 1 subfamily; involved in last step of pyrimidine biosynthesis; converts orotidine 5'-phosphate to UMP and carbon dioxide; OMP decarboxylase; OMPDCase; OMPdecase YP_001694162.1 involved in fifth step of pyrimidine biosynthesis; converts orotidine 5'-phosphate and diphosphate to orotate and 5-phospho-alpha-D-ribose 1-diphosphate YP_001694163.1 identified by glimmer YP_001694167.1 identified by match to protein family HMM PF00005 YP_001694168.1 identified by match to protein family HMM PF00497 YP_001694169.1 identified by match to protein family HMM PF00528; match to protein family HMM TIGR01726 YP_001694171.1 class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1 YP_001694172.1 identified by match to protein family HMM PF03070 YP_001694173.1 identified by glimmer YP_001694174.1 catalyzes the formation of 4-methyl-5-(2-phosphoethyl)-thiazole and ADP from 4-methyl-5-(2-hydroxyethyl)-thiazole and ATP YP_001694175.1 identified by match to protein family HMM PF02581; match to protein family HMM TIGR00693 YP_001694177.1 identified by match to protein family HMM PF00005 YP_001694179.1 identified by match to protein family HMM PF03070 YP_001694180.1 identified by match to protein family HMM TIGR02359 YP_001694181.1 identified by match to protein family HMM PF02110 YP_001694182.1 Condenses 4-methyl-5-(beta-hydroxyethyl)-thiazole monophosphate and 4-amino-5-hydroxymethyl pyrimidine pyrophosphate to form thiamine monophosphate YP_001694183.1 catalyzes the formation of 4-amino-2-methyl-5-diphosphomethylpyrimidine YP_001694184.1 identified by match to protein family HMM PF03965; match to protein family HMM TIGR02698 YP_001694186.1 identified by match to protein family HMM PF00122; match to protein family HMM PF00702; match to protein family HMM PF08282; match to protein family HMM TIGR01494; match to protein family HMM TIGR01511; match to protein family HMM TIGR01525 YP_001694187.1 identified by match to protein family HMM PF00205; match to protein family HMM PF02775; match to protein family HMM PF02776; match to protein family HMM TIGR02720 YP_001694188.1 identified by match to protein family HMM PF00903 YP_001694190.1 identified by glimmer YP_001694191.1 identified by match to protein family HMM PF04131 YP_001694192.1 identified by match to protein family HMM PF00528 YP_001694193.1 identified by match to protein family HMM PF00528 YP_001694195.1 identified by match to protein family HMM PF01547 YP_001694197.1 identified by match to protein family HMM PF01230 YP_001694198.1 identified by match to protein family HMM PF04074; match to protein family HMM TIGR00022 YP_001694201.1 identified by match to protein family HMM PF01238; match to protein family HMM TIGR00218 YP_001694204.1 identified by match to protein family HMM PF01134; match to protein family HMM PF03486; match to protein family HMM TIGR00275 YP_001694205.1 identified by match to protein family HMM PF02645 YP_001694206.1 identified by match to protein family HMM PF00440 YP_001694207.1 identified by match to protein family HMM PF00383 YP_001694208.1 Catalyzes the formation of uracil and 5-phospho-alpha-D-ribosy 1-diphosphate from UMP and diphosphate YP_001694209.1 hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates YP_001694211.1 identified by match to protein family HMM PF01094 YP_001694212.1 identified by match to protein family HMM PF02653 YP_001694213.1 identified by match to protein family HMM PF02653 YP_001694214.1 identified by match to protein family HMM PF00005 YP_001694215.1 identified by match to protein family HMM PF00005 YP_001694216.1 identified by match to protein family HMM PF00571 YP_001694217.1 recognizes the termination signals UGA and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF2; in some organisms control of PrfB protein levels is maintained through a +1 ribosomal frameshifting mechanism; this protein is similar to release factor 1 YP_001694218.1 identified by match to protein family HMM PF00005; match to protein family HMM TIGR02673 YP_001694219.1 identified by match to protein family HMM PF02687 YP_001694220.1 identified by match to protein family HMM PF00358; match to protein family HMM PF00367; match to protein family HMM PF02378; match to protein family HMM TIGR00826; match to protein family HMM TIGR00830; match to protein family HMM TIGR02003 YP_001694221.1 identified by match to protein family HMM PF03372 YP_001694222.1 identified by match to protein family HMM PF00270; match to protein family HMM PF00271 YP_001694223.1 catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase YP_001694224.1 dihydroorotate oxidase; dhodehase; dhodase; dhod; catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway; subclass 1A is a dimer formed by two identical PyrD subunits each containing an FMN group YP_001694225.1 required for the assembly and function of the DNAX complex which is required for the assembly of the beta subunit onto primed DNA YP_001694226.1 identified by match to protein family HMM PF00081; match to protein family HMM PF02777 YP_001694227.1 identified by match to protein family HMM PF06265 YP_001694228.1 23S rRNA m2A2503 methyltransferase; methylates the C2 position of the A2530 nucleotide in 23S rRNA; may be involved in antibiotic resistance YP_001694229.1 identified by match to protein family HMM PF04892 YP_001694230.1 identified by match to protein family HMM PF00005 YP_001694231.1 identified by match to protein family HMM PF00160 YP_001694233.1 identified by glimmer YP_001694234.1 binds to lower part of 30S body where it stabilizes two domains; required for efficient assembly of 30S; in Escherichia coli this protein has nuclease activity YP_001694236.1 identified by match to protein family HMM PF00561 YP_001694237.1 Essential for efficient processing of 16S rRNA YP_001694238.1 methylates guanosine-37 in various tRNAs; uses S-adenosyl-L-methionine to transfer methyl group to tRNA YP_001694239.1 identified by match to protein family HMM PF03477 YP_001694243.1 identified by match to protein family HMM PF02632 YP_001694244.1 catalyzes the reduction of 2 glutathione to glutathione disulfide; maintains high levels of reduced glutathione in the cytosol; involved in redox regulation and oxidative defense YP_001694245.1 identified by match to protein family HMM TIGR01730 YP_001694246.1 identified by match to protein family HMM PF00005 YP_001694247.1 identified by match to protein family HMM PF02687 YP_001694248.1 methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content YP_001694249.1 identified by match to protein family HMM PF01610 YP_001694251.1 identified by match to protein family HMM PF03551 YP_001694253.1 identified by glimmer YP_001694254.1 identified by match to protein family HMM PF00248 YP_001694256.1 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis YP_001694257.1 identified by match to protein family HMM PF00293 YP_001694258.1 identified by match to protein family HMM PF02896 YP_001694259.1 identified by match to protein family HMM PF06171 YP_001694260.1 identified by match to protein family HMM PF01433 YP_001694261.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00486 YP_001694262.1 identified by match to protein family HMM PF00512; match to protein family HMM PF02518 YP_001694264.1 identified by match to protein family HMM PF01136 YP_001694265.1 unwinds DNA YP_001694266.1 identified by match to protein family HMM PF01098 YP_001694267.1 identified by match to protein family HMM PF01965; match to protein family HMM TIGR01383 YP_001694268.1 identified by match to protein family HMM PF00702; match to protein family HMM TIGR01549 YP_001694269.1 negatively supercoils closed circular double-stranded DNA YP_001694270.1 acts to negatively regulates ftsZ ring formation by modulating the frequency and position of the ftsZ ring formation YP_001694272.1 identified by match to protein family HMM PF05717 YP_001694274.1 identified by match to protein family HMM PF08860 YP_001694275.1 identified by match to protein family HMM PF00293 YP_001694276.1 identified by match to protein family HMM PF00004; match to protein family HMM PF02151; match to protein family HMM PF07724; match to protein family HMM PF07728 YP_001694277.1 identified by match to protein family HMM PF08796 YP_001694278.1 identified by match to protein family HMM PF00528; match to protein family HMM TIGR01726 YP_001694279.1 identified by match to protein family HMM PF00005 YP_001694280.1 catalyzes the formation of 5,10-methenyltetrahydrofolate from 5,10-methylenetetrahydrofolate and subsequent formation of 10-formyltetrahydrofolate from 5,10-methenyltetrahydrofolate YP_001694281.1 identified by match to protein family HMM PF01256; match to protein family HMM TIGR00196 YP_001694282.1 Catalyzes D-ribose 5-phosphate --> D-ribulose 5-phosphate in the nonoxidative branch of the pentose phosphate pathway YP_001694283.1 catalyzes the transfer of phosphate between the C1 and C5 carbons of pentose YP_001694284.1 identified by match to protein family HMM PF08002 YP_001694285.1 catalyzes the formation of a purine and ribose phosphate from a purine nucleoside; in E. coli this enzyme functions in xanthosine degradation YP_001694286.1 identified by glimmer YP_001694287.1 identified by glimmer YP_001694288.1 identified by glimmer YP_001694289.1 identified by glimmer YP_001694290.1 catalyzes the reversible phosphorolysis of ribonucleosides and 2'- deoxyribonucleosides to the free base and (2'-deoxy)ribose-1- phosphate YP_001694292.1 binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase YP_001694293.1 catalyzes the formation of (R)-4'-phosphopantothenate in coenzyme A biosynthesis YP_001694294.1 identified by glimmer YP_001694295.1 identified by glimmer YP_001694296.1 identified by match to protein family HMM PF05175 YP_001694297.1 Catalyzes the reversible phosphorolysis of pyrimidines in the nucleotide synthesis salvage pathway YP_001694298.1 catalyzes the formation of D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-D-ribose-5-phosphate YP_001694299.1 Reclaims exogenous and endogenous cytidine and 2'-deoxycytidine molecules for UMP synthesis YP_001694300.1 identified by match to protein family HMM PF02608 YP_001694301.1 identified by match to protein family HMM PF00005 YP_001694302.1 identified by match to protein family HMM PF02653 YP_001694303.1 identified by match to protein family HMM PF02653 YP_001694304.1 identified by match to protein family HMM PF00665 YP_001694305.1 involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsX YP_001694306.1 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling YP_001694307.1 identified by glimmer YP_001694308.1 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling YP_001694309.1 catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids YP_001694311.1 identified by match to protein family HMM PF06149 YP_001694312.1 identified by match to protein family HMM PF06166 YP_001694313.1 catalyzes the removal of 5-oxoproline from various penultimate amino acid residues except L-proline YP_001694315.1 in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins YP_001694317.1 catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the tau chain serves as a scaffold to help in the dimerizaton of the alpha,epsilon and theta core complex; the gamma chain seems to interact with the delta and delta' subunits to transfer the beta subunit on the DNA YP_001694319.1 identified by match to protein family HMM PF00005; match to protein family HMM TIGR01978 YP_001694320.1 identified by match to protein family HMM PF01458; match to protein family HMM TIGR01981 YP_001694321.1 selenocysteine lyase; Selenocysteine reductase; Selenocysteine beta-lyase; SCL; identified by match to protein family HMM PF00266; match to protein family HMM PF01212; match to protein family HMM TIGR01979 YP_001694322.1 identified by match to protein family HMM PF01592; match to protein family HMM TIGR01994 YP_001694323.1 identified by match to protein family HMM PF01458; match to protein family HMM TIGR01980 YP_001694324.1 identified by glimmer YP_001694325.1 identified by match to protein family HMM PF00144; match to protein family HMM PF00768; match to protein family HMM PF07943 YP_001694326.1 identified by match to protein family HMM PF01594 YP_001694327.1 identified by match to protein family HMM PF00455; match to protein family HMM PF08220; match to protein family HMM PF08279 YP_001694328.1 identified by match to protein family HMM PF00294; match to protein family HMM TIGR03168 YP_001694329.1 identified by match to protein family HMM PF00359; match to protein family HMM PF02378; match to protein family HMM PF02379; match to protein family HMM TIGR00829; match to protein family HMM TIGR00848; match to protein family HMM TIGR01427 YP_001694330.1 identified by glimmer YP_001694331.1 identified by match to protein family HMM PF01580 YP_001694333.1 identified by match to protein family HMM PF00266 YP_001694334.1 Required for the synthesis of the thiazole moiety YP_001694335.1 identified by match to protein family HMM PF00756 YP_001694336.1 identified by glimmer YP_001694337.1 identified by glimmer YP_001694339.1 identified by glimmer YP_001694340.1 identified by match to protein family HMM PF02384 YP_001694341.1 identified by match to protein family HMM PF01420 YP_001694343.1 identified by match to protein family HMM PF05012; match to protein family HMM TIGR01550 YP_001694344.1 identified by match to protein family HMM PF00589; match to protein family HMM PF02899 YP_001694345.1 identified by match to protein family HMM PF01420 YP_001694346.1 identified by match to protein family HMM PF00270; match to protein family HMM PF00271; match to protein family HMM PF04313; match to protein family HMM PF04851 YP_001694348.1 identified by match to protein family HMM PF01316; match to protein family HMM PF02863 YP_001694349.1 x-pro dipeptidyl-peptidase; x-prolyl-dipeptidyl aminopeptidase; x-pdap; catalyzes the removal of N-terminal dipeptides when proline is the penultimate residue YP_001694350.1 Catalyzes DNA-template-directed extension of the 3'-end of a DNA strand by one nucleotide at a time. Proposed to be responsible for the synthesis of the lagging strand. In the low GC gram positive bacteria this enzyme is less processive and more error prone than its counterpart in other bacteria. YP_001694351.1 catalyzes the formation of D-fructose 1,6-bisphosphate from D-fructose 6-phosphate in glycolysis YP_001694352.1 catalyzes the formation of phosphoenolpyruvate from pyruvate YP_001694353.1 identified by glimmer YP_001694358.1 identified by match to protein family HMM PF09323 YP_001694359.1 identified by match to protein family HMM PF03773 YP_001694360.1 identified by glimmer YP_001694361.1 identified by match to protein family HMM PF00575 YP_001694362.1 identified by match to protein family HMM PF03926 YP_001694363.1 identified by match to protein family HMM PF04024 YP_001694364.1 identified by glimmer YP_001694365.1 identified by glimmer YP_001694366.1 identified by match to protein family HMM PF00005 YP_001694367.1 identified by match to protein family HMM PF02687 YP_001694368.1 identified by match to protein family HMM PF01988 YP_001694370.1 identified by match to protein family HMM PF00266; match to protein family HMM PF01212; match to protein family HMM PF01276; match to protein family HMM PF03711 YP_001694371.1 catalyzes the formation of spermidine from putrescine and S-adenosylmethioninamine YP_001694372.1 identified by match to protein family HMM PF03435 YP_001694373.1 identified by match to protein family HMM PF00278; match to protein family HMM TIGR01047 YP_001694374.1 catalyzes the formation of carbamoylputrescine from agmatine in the arginine decarboxylase pathway of putrescine biosynthesis YP_001694375.1 identified by match to protein family HMM PF00795; match to protein family HMM TIGR03381 YP_001694376.1 identified by match to protein family HMM PF00702; match to protein family HMM PF05116; match to protein family HMM PF08282; match to protein family HMM TIGR00099; match to protein family HMM TIGR01484 YP_001694378.1 identified by match to protein family HMM PF02517 YP_001694380.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466 YP_001694381.1 lipoprotein signal peptidase; integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis YP_001694382.1 identified by match to protein family HMM PF00849; match to protein family HMM PF01479; match to protein family HMM TIGR00005 YP_001694383.1 identified by match to protein family HMM PF00753; match to protein family HMM PF01473 YP_001694384.1 catalyzes the formation of glutamate 5-phosphate from glutamate in proline biosynthesis YP_001694385.1 Catalyzes the phosphorylation of L-glutamate during the proline biosynthesis pathway YP_001694386.1 identified by match to protein family HMM PF01210; match to protein family HMM PF03807; match to protein family HMM TIGR00112 YP_001694387.1 catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to thymidine monophosphate (dTMP) to form thymidine diphosphate (dTDP) YP_001694388.1 catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the delta' subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA. YP_001694389.1 in Bacillus subtilis this protein is involved in the negative regulation of DNA replication initiation; interacts with DnaN and DnaA YP_001694390.1 identified by match to protein family HMM PF00590; match to protein family HMM TIGR00096 YP_001694391.1 TrmFO; Gid; glucose-inhibited division protein; similar to GidA; the gene from Bacillus subtilis encodes a tRNA-methyltransferase that utilizes folate as the carbon donor and bound flavin as reductant; modifies tRNA at position 54 (uridine) of the T-psi loop to form a C5-methyluridine YP_001694392.1 Catalyzes the phosphorylation of UMP to UDP YP_001694393.1 Rrf; Frr; ribosome-recycling factor; release factor 4; RF4; recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G; A GTPase-dependent process results in release of 50S from 70S; inhibited by release factor RF-1; essential for viability; structurally similar to tRNAs YP_001694395.1 identified by match to protein family HMM PF06855 YP_001694396.1 identified by match to protein family HMM PF02562 YP_001694397.1 identified by match to protein family HMM PF00583 YP_001694398.1 identified by match to protein family HMM PF00633; match to protein family HMM TIGR00426; match to protein family HMM TIGR01259 YP_001694399.1 identified by match to protein family HMM PF03772; match to protein family HMM TIGR00360; match to protein family HMM TIGR00361 YP_001694401.1 identified by match to protein family HMM PF00005 YP_001694403.1 identified by glimmer YP_001694404.1 IF-3 has several functions that are required and promote translation initiation including; preventing association of 70S by binding to 30S; monitoring codon-anticodon interactions by promoting disassociation of fMet-tRNA(fMet) from initiation complexes formed on leaderless mRNAs or incorrectly bound noninitiatior tRNAs and complexes with noncanonical start sites; stimulates codon-anticodon interactions at P-site; involved in moving mRNA to the P-site; and in recycling subunits YP_001694405.1 identified by match to protein family HMM PF01632; match to protein family HMM TIGR00001 YP_001694406.1 binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit YP_001694407.1 identified by match to protein family HMM PF00903 YP_001694408.1 responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the pyrD subunit to the ultimate electron acceptor NAD(+) YP_001694409.1 dihydroorotate oxidase b; dhodehase b; dhodase b; dhod b; catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway, using a flavin nucleotide as an essential cofactor; subclass 1B is a heterotetramer consisting of two PyrDB subunits, similar to the PyrDA subunits and two PyrK subunits YP_001694410.1 identified by match to protein family HMM PF01473; match to protein family HMM PF01832 YP_001694411.1 identified by match to protein family HMM PF05670; match to protein family HMM PF05833 YP_001694412.1 identified by match to protein family HMM PF02130; match to protein family HMM TIGR00043 YP_001694413.1 identified by match to protein family HMM PF01219 YP_001694414.1 Era; Escherichia coli Ras-like protein; Bex; Bacillus Era-complementing segment; essential protein in Escherichia coli that is involved in many cellular processes; GTPase; binds the cell membrane through apparent C-terminal domain; mutants are arrested during the cell cycle; Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome YP_001694415.1 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases YP_001694416.1 catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; involved in coenzyme A biosynthesis YP_001694417.1 identified by match to protein family HMM PF07690 YP_001694418.1 in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif YP_001694419.1 identified by match to protein family HMM PF03840; match to protein family HMM TIGR00810 YP_001694420.1 identified by match to protein family HMM PF00575; match to protein family HMM PF00773; match to protein family HMM PF08206; match to protein family HMM TIGR00358; match to protein family HMM TIGR02063 YP_001694421.1 binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation YP_001694422.1 with TehA confers resistance to tellurite YP_001694423.1 identified by match to protein family HMM PF06054 YP_001694424.1 identified by match to protein family HMM PF01432; match to protein family HMM PF08439; match to protein family HMM TIGR00181 YP_001694425.1 identified by match to protein family HMM PF01596; match to protein family HMM PF08241 YP_001694426.1 cis/trans isomerase of peptidylprolyl; PPIase; membrane-bound lipoprotein YP_001694427.1 identified by match to protein family HMM PF00665 YP_001694429.1 identified by match to protein family HMM PF00300 YP_001694430.1 identified by match to protein family HMM PF04073 YP_001694431.1 identified by match to protein family HMM PF04018 YP_001694432.1 identified by match to protein family HMM PF01183 YP_001694433.1 forms a homotrimer; catalyzes the acetylation of glucosamine-1-phosphate and uridylation of N-acetylglucosamine-1-phosphate to produce UDP-GlcNAc; function in cell wall synthesis YP_001694434.1 identified by match to protein family HMM PF00293 YP_001694436.1 enables the cleavage of the glycosidic bond in both 5'-methylthioadenosine and S-adenosylhomocysteine YP_001694437.1 identified by match to protein family HMM PF04394 YP_001694438.1 3'-5' exonuclease of DNA polymerase III YP_001694439.1 identified by match to protein family HMM PF03009 YP_001694443.1 identified by match to protein family HMM PF02683 YP_001694444.1 identified by match to protein family HMM PF00578; match to protein family HMM PF08534 YP_001694445.1 identified by match to protein family HMM PF00324 YP_001694446.1 identified by match to protein family HMM PF01297 YP_001694447.1 identified by match to protein family HMM PF04270; match to protein family HMM TIGR01363 YP_001694448.1 identified by match to protein family HMM PF04270; match to protein family HMM TIGR01363 YP_001694449.1 identified by match to protein family HMM PF04270 YP_001694450.1 identified by glimmer YP_001694451.1 identified by glimmer YP_001694452.1 catalyzes the release of the N-terminal amino acid from a tripeptide YP_001694453.1 identified by match to protein family HMM PF00762; match to protein family HMM TIGR00109 YP_001694454.1 identified by match to protein family HMM PF01741; match to protein family HMM TIGR00220 YP_001694455.1 identified by match to protein family HMM PF04138 YP_001694456.1 identified by match to protein family HMM PF06177 YP_001694457.1 identified by glimmer YP_001694458.1 catalyzes the formation of 4-aspartyl phosphate from aspartate 4-semialdehyde YP_001694459.1 catalyzes the formation of dihydrodipicolinate from L-aspartate 4-semialdehyde and pyruvate in lysine and diaminopimelate biosynthesis YP_001694460.1 in Escherichia coli this protein is involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2-thiouridine, which is found in the wobble position of some tRNAs and affects ribosomal frameshifting; shows potassium-dependent dimerization and GTP hydrolysis; also involved in regulation of glutamate-dependent acid resistance and activation of gadE YP_001694461.1 4-OT; member of subfamily 5; forms a dimer; the function in the Escherichia coli cell is unknown YP_001694462.1 catalyzes the formation of thymidine 5'-phosphate from thymidine YP_001694463.1 identified by match to protein family HMM PF00583 YP_001694464.1 recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2 YP_001694465.1 identified by match to protein family HMM PF05175; match to protein family HMM PF08241; match to protein family HMM PF08242; match to protein family HMM TIGR00536; match to protein family HMM TIGR03387 YP_001694466.1 identified by match to protein family HMM PF01300; match to protein family HMM TIGR00057 YP_001694467.1 identified by match to protein family HMM PF00583 YP_001694468.1 catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate YP_001694471.1 identified by match to protein family HMM PF06207 YP_001694472.1 identified by match to protein family HMM PF01938; match to protein family HMM PF05958; match to protein family HMM TIGR00479 YP_001694474.1 identified by glimmer YP_001694475.1 identified by match to protein family HMM PF01497 YP_001694476.1 identified by match to protein family HMM PF01032 YP_001694477.1 identified by match to protein family HMM PF01032 YP_001694478.1 identified by match to protein family HMM PF00005 YP_001694479.1 identified by match to protein family HMM PF07674 YP_001694482.1 identified by match to protein family HMM PF00239; match to protein family HMM PF07508 YP_001694485.1 identified by glimmer YP_001694486.1 identified by match to protein family HMM PF03747 YP_001694487.1 identified by match to protein family HMM PF00781; match to protein family HMM TIGR00147 YP_001694488.1 identified by match to protein family HMM PF00128; match to protein family HMM PF02903 YP_001694489.1 identified by glimmer YP_001694490.1 identified by match to protein family HMM PF00583 YP_001694491.1 identified by glimmer YP_001694493.1 identified by match to protein family HMM PF01098 YP_001694494.1 catalyzes the formation of oxaloacetate from phosphoenolpyruvate YP_001694495.1 identified by match to protein family HMM PF04392 YP_001694496.1 identified by match to protein family HMM PF02653 YP_001694497.1 synthesizes RNA primers at the replication forks YP_001694498.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; primary sigma factor of bacterium YP_001694499.1 identified by match to protein family HMM PF01883 YP_001694500.1 identified by match to protein family HMM PF00534 YP_001694501.1 identified by match to protein family HMM PF00534 YP_001694502.1 identified by match to protein family HMM PF04024 YP_001694504.1 essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication YP_001694506.1 identified by glimmer YP_001694507.1 identified by glimmer YP_001694508.1 adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active YP_001694509.1 identified by match to protein family HMM PF00583 YP_001694510.1 identified by match to protein family HMM PF00571; match to protein family HMM PF07085; match to protein family HMM PF08279 YP_001694511.1 catalyzes the removal of N-terminal amino acids from peptides and arylamides YP_001694512.1 identified by match to protein family HMM PF00580; match to protein family HMM TIGR01073 YP_001694513.1 Involved in DNA double-strand break repair and recombination. Promotes the annealing of complementary single-stranded DNA and by simulation of RAD51 recombinase YP_001694514.1 identified by match to protein family HMM PF00117; match to protein family HMM PF07722 YP_001694515.1 modulates transcription in response to the NADH/NAD(+) redox state YP_001694517.1 identified by match to protein family HMM PF08866 YP_001694518.1 identified by match to protein family HMM PF00266 YP_001694519.1 catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP YP_001694520.1 identified by match to protein family HMM PF01928 YP_001694521.1 identified by match to protein family HMM PF04607 YP_001694522.1 catalyzes the phosphorylation of NAD to NADP YP_001694523.1 identified by match to protein family HMM PF00849; match to protein family HMM TIGR00005 YP_001694524.1 in Salmonella this enzyme is required for ethanolamine catabolism; has higher affinity for CoA than Pta YP_001694525.1 identified by match to protein family HMM PF02575; match to protein family HMM TIGR00103 YP_001694526.1 identified by match to protein family HMM PF06912 YP_001694527.1 identified by match to protein family HMM PF00829; match to protein family HMM TIGR00061 YP_001694528.1 identified by match to protein family HMM PF04327 YP_001694529.1 involved in the peptidyltransferase reaction during translation YP_001694531.1 catalyzes the formation of FMN from riboflavin and the formation of FAD from FMN; in Bacillus the ribC gene has both flavokinase and FAD synthetase activities YP_001694532.1 identified by match to protein family HMM PF02588 YP_001694533.1 identified by match to protein family HMM PF02645; match to protein family HMM TIGR00762 YP_001694534.1 identified by match to protein family HMM PF00216 YP_001694535.1 identified by match to protein family HMM PF00005 YP_001694536.1 identified by match to protein family HMM TIGR01716 YP_001694537.1 identified by match to protein family HMM PF07690 YP_001694538.1 this protein catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction; essential for DNA replication and repair of damaged DNA; similar to ligase LigB YP_001694539.1 identified by match to protein family HMM PF00128; match to protein family HMM PF02922; match to protein family HMM TIGR02104 YP_001694541.1 identified by match to protein family HMM PF00171 YP_001694542.1 catalyzes the transfer of a segment of a 1,4-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain YP_001694543.1 catalyzes the formation of ADP-glucose and diphosphate from ATP and alpha-D-glucose 1-phosphate YP_001694544.1 identified by match to protein family HMM PF00483; match to protein family HMM TIGR02092 YP_001694545.1 catalyzes the formation of alpha-1,4-glucan chains from ADP-glucose YP_001694546.1 identified by match to protein family HMM PF02595; match to protein family HMM TIGR00045 YP_001694547.1 identified by match to protein family HMM PF07997 YP_001694548.1 enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis YP_001694549.1 identified by match to protein family HMM PF00589 YP_001694550.1 identified by match to protein family HMM TIGR02774 YP_001694551.1 identified by match to protein family HMM PF00580; match to protein family HMM TIGR02785 YP_001694553.1 identified by glimmer YP_001694554.1 identified by match to protein family HMM PF00746; match to protein family HMM PF04650; match to protein family HMM PF05342; match to protein family HMM PF07501; match to protein family HMM PF07580; match to protein family HMM PF07581; match to protein family HMM TIGR01167; match to protein family HMM TIGR01168 YP_001694555.1 identified by match to protein family HMM PF01610 YP_001694557.1 identified by match to protein family HMM PF06970 YP_001694558.1 identified by match to protein family HMM PF00145; match to protein family HMM TIGR00675 YP_001694562.1 identified by match to protein family HMM PF02517 YP_001694564.1 identified by match to protein family HMM PF08843 YP_001694567.1 identified by match to protein family HMM PF02534 YP_001694572.1 identified by match to protein family HMM PF01551; match to protein family HMM PF05257 YP_001694577.1 identified by glimmer YP_001694578.1 identified by glimmer YP_001694586.1 identified by match to protein family HMM PF06414 YP_001694587.1 identified by glimmer YP_001694588.1 identified by glimmer YP_001694589.1 identified by match to protein family HMM PF00302 YP_001694590.1 identified by match to protein family HMM PF01446 YP_001694592.1 identified by match to protein family HMM PF00128; match to protein family HMM PF02903 YP_001694595.1 essential GTPase; functions in ribosome assembly; binds a unique part of the 23S rRNA; interacts with ribosomal protein L25(Ctc) YP_001694596.1 RNH2; RNase HII; binds manganese; endonuclease which specifically degrades the RNA of RNA-DNA hybrids YP_001694597.1 identified by match to protein family HMM PF00654; match to protein family HMM PF02080 YP_001694598.1 site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; cell division protein FtsK may regulate the XerS YP_001694599.1 identified by match to protein family HMM PF01527 YP_001694600.1 identified by match to protein family HMM PF00665 YP_001694601.1 identified by match to protein family HMM PF01554; match to protein family HMM TIGR00797 YP_001694602.1 catalyzes the formation of N-carbamoyl-L-aspartate from (S)-dihydroorotate in pyrimidine biosynthesis YP_001694603.1 7,8-dihydro-8-oxoguanine-triphosphatase; 8-oxo-dGTPase; dGTP pyrophosphohydrolase; identified by match to protein family HMM PF00293 YP_001694604.1 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine YP_001694605.1 identified by match to protein family HMM PF00702; match to protein family HMM TIGR01549; match to protein family HMM TIGR02254 YP_001694606.1 identified by glimmer YP_001694607.1 identified by match to protein family HMM PF00005; match to protein family HMM PF00664 YP_001694608.1 identified by match to protein family HMM PF00005 YP_001694610.1 identified by match to protein family HMM PF00440 YP_001694611.1 identified by match to protein family HMM PF03610; match to protein family HMM TIGR02364 YP_001694612.1 identified by match to protein family HMM PF02734; match to protein family HMM TIGR02365 YP_001694613.1 with DhaL and DhaM forms dihydroxyacetone kinase, which is responsible for phosphorylating dihydroxyacetone; DhaK is the dihydroxyacetone binding subunit of the dihydroxyacetone kinase YP_001694614.1 identified by match to protein family HMM TIGR02366 YP_001694615.1 similar to DhaK; in Lactococcus lactis this protein froms a stable complex with DhaS and activates transcription of the dha operon in the presence of dihydroxyacetone YP_001694616.1 identified by match to protein family HMM PF08020 YP_001694617.1 identified by match to protein family HMM PF03692 YP_001694618.1 identified by match to protein family HMM PF00391; match to protein family HMM PF02896; match to protein family HMM PF05524; match to protein family HMM TIGR01417 YP_001694619.1 identified by match to protein family HMM PF00381; match to protein family HMM TIGR01003 YP_001694620.1 identified by match to protein family HMM PF00462; match to protein family HMM TIGR02194 YP_001694621.1 Catalyzes the rate-limiting step in dNTP synthesis YP_001694622.1 B2 or R2 protein; type 1b enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdE YP_001694623.1 identified by match to protein family HMM PF00455; match to protein family HMM PF08220; match to protein family HMM PF08279 YP_001694625.1 catalyzes the formation of 6-phospho-galactose from a 6-phospho-beta-galactoside YP_001694626.1 identified by match to protein family HMM PF02302; match to protein family HMM PF02378; match to protein family HMM TIGR00394; match to protein family HMM TIGR00410; match to protein family HMM TIGR00853 YP_001694627.1 pts system lactose-specific eiia component; eiia-lac; eiii-lac; identified by match to protein family HMM PF02255; match to protein family HMM TIGR00823 YP_001694628.1 identified by match to protein family HMM PF00874; match to protein family HMM PF03123 YP_001694629.1 catalyzes the reversible reaction of dihydroxyacetone phosphate with glyceraldehyde 3-phosphate to produce tagatose 1,6-bisphosphate; in Streptococcus pyogenes there are two paralogs of tagatose-bisphosphate aldolase, encoded by lacD1 and lacD2; expression of lacD1 is highly regulated by environmental conditions while lacD2 specializes in an efficient utilization of carbohydrate sources YP_001694630.1 catalyzes the formation of tagatose 1,6-bisphosphate from tagatose 6-phosphate and ATP YP_001694631.1 catalyzes the interconversion of galactose 6-phosphate to tagatose 6-phosphate YP_001694632.1 catalyzes the interconversion of galactose 6-phosphate to tagatose 6-phosphate; tagatose pathway for galactose utilization YP_001694633.1 identified by glimmer YP_001694634.1 identified by match to protein family HMM PF01609 YP_001694637.1 binds to the ribosome on the universally-conserved alpha-sarcin loop YP_001694638.1 identified by match to protein family HMM PF00149 YP_001694639.1 identified by match to protein family HMM PF02463; match to protein family HMM TIGR00634 YP_001694640.1 identified by match to protein family HMM PF01316; match to protein family HMM PF02863 YP_001694641.1 identified by match to protein family HMM PF01479; match to protein family HMM PF01728; match to protein family HMM TIGR00478 YP_001694642.1 identified by match to protein family HMM PF00348 YP_001694643.1 catalyzes the bidirectional exonucleolytic cleavage of DNA YP_001694644.1 bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides YP_001694645.1 functions in pyrimidine salvage; pyrimidine ribonucleoside kinase; phosphorylates nucleosides or dinucleosides to make UMP or CMP using ATP or GTP as the donor YP_001694647.1 catalyzes isomerization of specific uridines in RNA to pseudouridine; responsible for residues in T loops of many tRNAs YP_001694649.1 identified by match to protein family HMM PF01226 YP_001694650.1 identified by match to protein family HMM PF04203; match to protein family HMM TIGR01076 YP_001694651.1 negatively supercoils closed circular double-stranded DNA YP_001694652.1 Converts (S)-lactate and NAD(+) to pyruvate and NADH YP_001694653.1 identified by match to protein family HMM PF00520; match to protein family HMM PF07885 YP_001694654.1 identified by match to protein family HMM PF05016; match to protein family HMM TIGR02385 YP_001694656.1 identified by match to protein family HMM PF00753 YP_001694657.1 identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF00989; match to protein family HMM PF02518; match to protein family HMM TIGR00229 YP_001694658.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00486 YP_001694659.1 identified by match to protein family HMM PF00633; match to protein family HMM PF00730; match to protein family HMM TIGR01084 YP_001694660.1 identified by glimmer YP_001694661.1 catalyzes the formation of 10-formyltetrahydrofolate from formate and tetrahydrofolate YP_001694662.1 identified by match to protein family HMM PF04127; match to protein family HMM TIGR02114 YP_001694663.1 decarboxylates 4-phosphopantothenoylcysteine to form 4'-phosphopantotheine. YP_001694666.1 identified by match to protein family HMM PF02829; match to protein family HMM PF08279 YP_001694667.1 similart to NTP pyrophosphohydrolase including oxidative damage repair enzymes; identified by match to protein family HMM PF00293 YP_001694668.1 identified by match to protein family HMM PF00583 YP_001694670.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion YP_001694671.1 identified by match to protein family HMM PF00497; match to protein family HMM PF00528; match to protein family HMM TIGR01726 YP_001694672.1 identified by match to protein family HMM PF00005 YP_001694673.1 catalyzes the formation of D-glucono-1,5-lactone 6-phosphate from D-glucose 6-phosphate YP_001694674.1 identified by match to protein family HMM PF00448; match to protein family HMM PF02881; match to protein family HMM TIGR00064 YP_001694675.1 identified by match to protein family HMM PF00702; match to protein family HMM PF05116; match to protein family HMM PF08282; match to protein family HMM TIGR00099; match to protein family HMM TIGR01484 YP_001694676.1 identified by match to protein family HMM PF00702; match to protein family HMM PF05116; match to protein family HMM PF08282; match to protein family HMM TIGR00099; match to protein family HMM TIGR01484 YP_001694677.1 identified by match to protein family HMM PF02463; match to protein family HMM PF06470; match to protein family HMM TIGR02168 YP_001694678.1 cytoplasmic enzyme involved in processing rRNA and some mRNAs; substrates typically have dsRNA regions; forms a homodimer; have N-terminal nuclease and C-terminal RNA-binding domains; requires magnesium as preferred ion for activity YP_001694679.1 identified by match to protein family HMM PF00478; match to protein family HMM TIGR01306 YP_001694682.1 isopropylmalate isomerase; alpha-ipm isomerase; ipmi YP_001694683.1 identified by match to protein family HMM PF06961 YP_001694684.1 catalyzes the oxidation of 3-isopropylmalate to 3-carboxy-4-methyl-2-oxopentanoate in leucine biosynthesis YP_001694685.1 identified by match to protein family HMM PF00682; match to protein family HMM PF08502 YP_001694686.1 identified by match to protein family HMM PF04237 YP_001694687.1 identified by match to protein family HMM PF03932 YP_001694688.1 identified by match to protein family HMM PF04304 YP_001694689.1 catalyzes the ATP-dependent breakage of single-stranded DNA followed by passage and rejoining, maintains net negative superhelicity YP_001694690.1 identified by glimmer YP_001694691.1 identified by glimmer YP_001694692.1 identified by match to protein family HMM PF02481; match to protein family HMM TIGR00732 YP_001694693.1 LicC regulates expression of LPS epitopes in Haemophilus influenzae; identified by match to protein family HMM PF00483 YP_001694694.1 LicB regulates expression of LPS epitopes in Haemophilus influenzae; identified by match to protein family HMM PF00892 YP_001694695.1 identified by match to protein family HMM PF01633; match to protein family HMM PF01636 YP_001694696.1 identified by match to protein family HMM PF08240 YP_001694697.1 4-diphosphocytidyl-2C-methyl-D-erythritol synthase; MEPcytidylyltransferase; MCT; 4-diphosphocytidyl-2C-methyl-D-erythritol synthase; MEP cytidylyltransferase; MCT; catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate; involved in isoprenoid and isopentenyl-PP biosynthesis; forms homodimers YP_001694698.1 identified by match to protein family HMM PF01943; match to protein family HMM PF03023 YP_001694699.1 identified by match to protein family HMM PF04991 YP_001694700.1 four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate; CarB is responsible for the amidotransferase activity YP_001694701.1 catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers YP_001694702.1 catalyzes the transfer of the carbamoyl moiety from carbamoyl phosphate to L- aspartate in pyrimidine biosynthesis YP_001694703.1 regulates pyrimidine biosynthesis by binding to the mRNA of the pyr genes, also has been shown to have uracil phosphoribosyltransferase activity YP_001694704.1 identified by match to protein family HMM PF00633; match to protein family HMM PF00730; match to protein family HMM TIGR01083 YP_001694705.1 identified by match to protein family HMM PF02620 YP_001694707.1 identified by match to protein family HMM PF00005 YP_001694708.1 metalloprotease YP_001694709.1 identified by match to protein family HMM PF04011 YP_001694710.1 glucose-inhibited division protein B; SAM-dependent methyltransferase; methylates the N7 position of guanosine in position 527 of 16S rRNA YP_001694711.1 identified by match to protein family HMM PF00589; match to protein family HMM PF02920 YP_001694712.1 identified by match to protein family HMM PF09035 YP_001694715.1 identified by match to protein family HMM PF04545; match to protein family HMM PF08281 YP_001694717.1 identified by match to protein family HMM PF01381 YP_001694718.1 identified by match to protein family HMM PF00009; match to protein family HMM PF00679; match to protein family HMM PF03144; match to protein family HMM PF03764; match to protein family HMM TIGR00231 YP_001694719.1 regulates the transcription of tet(M) by attenuation YP_001694721.1 identified by match to protein family HMM PF00877 YP_001694725.1 identified by match to protein family HMM PF07275 YP_001694727.1 identified by match to protein family HMM PF01610 YP_001694729.1 identified by match to protein family HMM PF00398 YP_001694730.1 identified by match to protein family HMM PF01381; match to protein family HMM PF02486 YP_001694731.1 identified by match to protein family HMM PF01580 YP_001694732.1 identified by match to protein family HMM PF06125 YP_001694733.1 identified by match to protein family HMM PF06125 YP_001694735.1 identified by match to protein family HMM PF00860; match to protein family HMM TIGR00801 YP_001694736.1 identified by match to protein family HMM PF00448; match to protein family HMM PF02881; match to protein family HMM PF02978; match to protein family HMM TIGR00959 YP_001694737.1 identified by match to protein family HMM PF04297; match to protein family HMM PF04967; match to protein family HMM PF08281 YP_001694738.1 identified by match to protein family HMM PF09148 YP_001694739.1 identified by match to protein family HMM PF01966 YP_001694740.1 identified by match to protein family HMM PF00702; match to protein family HMM PF05116; match to protein family HMM PF08282; match to protein family HMM TIGR00099; match to protein family HMM TIGR01484 YP_001694741.1 identified by match to protein family HMM PF02037 YP_001694742.1 this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site YP_001694743.1 may be involved in chromosome condensation; overexpression in Escherichia coli protects against decondensation by camphor; overexpressing the protein results in an increase in supercoiling YP_001694744.1 may be involved in chromosome condensation; overexpression in Escherichia coli protects against decondensation by camphor; overexpressing the protein results in an increase in supercoiling YP_001694745.1 identified by match to protein family HMM PF01817; match to protein family HMM TIGR01805 YP_001694746.1 An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group YP_001694747.1 identified by match to protein family HMM PF01368; match to protein family HMM PF02272 YP_001694748.1 RpmE2; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster do not have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome YP_001694749.1 identified by glimmer YP_001694750.1 identified by glimmer YP_001694751.1 identified by glimmer YP_001694753.1 converts 2-oxoglutarate to glutamate; in Escherichia coli this enzyme plays a role in glutamate synthesis when the cell is under energy restriction; uses NADPH; forms a homohexamer YP_001694755.1 identified by glimmer YP_001694757.1 identified by glimmer YP_001694758.1 identified by glimmer YP_001694760.1 identified by match to protein family HMM PF01527 YP_001694761.1 identified by match to protein family HMM PF00665 YP_001694762.1 produces ATP from ADP in the presence of a proton gradient across the membrane; the D subunit is part of the catalytic core of the ATP synthase complex YP_001694763.1 produces ATP from ADP in the presence of a proton gradient across the membrane; the B subunit is part of the catalytic core of the ATP synthase complex YP_001694764.1 produces ATP from ADP in the presence of a proton gradient across the membrane; the A subunit is part of the catalytic core of the ATP synthase complex YP_001694765.1 produces ATP from ADP in the presence of a proton gradient across the membrane; the F subunit is part of the catalytic core of the ATP synthase complex YP_001694766.1 identified by match to protein family HMM PF01992 YP_001694768.1 produces ATP from ADP in the presence of a proton gradient across the membrane; the K subunit is a nonenzymatic component which binds the dimeric form by interacting with the G and E subunits YP_001694769.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit I is part of the membrane proton channel. YP_001694771.1 identified by match to protein family HMM PF00480 YP_001694772.1 identified by match to protein family HMM PF01118; match to protein family HMM PF01408; match to protein family HMM PF02894; match to protein family HMM PF03447 YP_001694773.1 identified by match to protein family HMM PF02012; match to protein family HMM PF02973 YP_001694774.1 identified by match to protein family HMM PF04074; match to protein family HMM TIGR00022 YP_001694775.1 identified by match to protein family HMM PF00474; match to protein family HMM TIGR00813 YP_001694776.1 identified by match to protein family HMM PF00701 YP_001694777.1 Converts N-acetylmannosamine-6-phosphate to N-acetylglucosamine-6-phosphate YP_001694778.1 identified by match to protein family HMM PF01380; match to protein family HMM PF01418 YP_001694779.1 identified by match to protein family HMM PF02517 YP_001694783.1 identified by match to protein family HMM PF00005 YP_001694784.1 identified by match to protein family HMM PF00005 YP_001694786.1 identified by match to protein family HMM PF02517 YP_001694787.1 identified by match to protein family HMM PF01610 YP_001694789.1 present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulates GTPase activity of translation factors YP_001694790.1 binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit YP_001694791.1 identified by match to protein family HMM PF01979; match to protein family HMM PF07969 YP_001694792.1 identified by match to protein family HMM PF00005; match to protein family HMM PF00664 YP_001694793.1 identified by match to protein family HMM PF00005; match to protein family HMM PF00664 YP_001694794.1 identified by match to protein family HMM PF01625; match to protein family HMM PF01641; match to protein family HMM TIGR00357; match to protein family HMM TIGR00401 YP_001694796.1 catalyzes the formation of O-phospho-L-homoserine from L-homoserine in threonine biosynthesis from asparate YP_001694797.1 catalyzes the formation of L-aspartate 4-semialdehyde from L-homoserine YP_001694798.1 enables recognition and targeting of proteins for proteolysis, involved in negative regulation of competence YP_001694801.1 identified by match to protein family HMM PF00535 YP_001694802.1 identified by match to protein family HMM PF00534 YP_001694803.1 identified by match to protein family HMM PF04991 YP_001694804.1 identified by match to protein family HMM PF03816; match to protein family HMM TIGR00350 YP_001694805.1 catalyzes the formation of phenylpyruvate from prephenate in phenylalanine biosynthesis YP_001694806.1 identified by match to protein family HMM PF01202 YP_001694807.1 catalyzes the formation of 5-O-(1-carboxyvinyl)-3-phosphoshikimate from phosphoenolpyruvate and 3-phosphoshikimate in tryptophan biosynthesis YP_001694808.1 identified by match to protein family HMM PF06133 YP_001694809.1 catalyzes the formation of 4-hydroxyphenylpyruvate from prephenate YP_001694810.1 catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis YP_001694811.1 catalyzes the formation of 3-dehydroquinate from 3-deoxy-arabino-heptulonate 7-phosphate; functions in aromatic amino acid biosynthesis YP_001694812.1 AroE; catalyzes the conversion of shikimate to 3-dehydroshikimate YP_001694813.1 catalyzes the dehydration of 3-dehydroquinate to form 3-dehydroshikimate in aromatic amino acid biosynthesis YP_001694816.1 identified by match to protein family HMM PF00005 YP_001694817.1 converts 1,4-alpha-D-glucans to maltodextrin YP_001694818.1 Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_001694819.1 identified by match to protein family HMM PF04525 YP_001694820.1 identified by match to protein family HMM PF01547 YP_001694821.1 identified by match to protein family HMM PF00528 YP_001694822.1 identified by match to protein family HMM PF00528 YP_001694823.1 identified by match to protein family HMM PF00005; match to protein family HMM PF08402 YP_001694824.1 catalyzes the reduction of UDP-N-acetylglucosamine enolpyruvate to form UDP-N-acetylmuramate in peptidoglycan biosynthesis YP_001694825.1 identified by glimmer YP_001694826.1 identified by glimmer YP_001694827.1 identified by match to protein family HMM PF03306; match to protein family HMM TIGR01252 YP_001694828.1 identified by match to protein family HMM PF00392 YP_001694829.1 identified by match to protein family HMM PF00497 YP_001694830.1 identified by match to protein family HMM PF01895; match to protein family HMM TIGR02135 YP_001694831.1 ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation YP_001694832.1 ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation YP_001694833.1 identified by match to protein family HMM PF00528; match to protein family HMM TIGR00974 YP_001694834.1 identified by match to protein family HMM PF00528; match to protein family HMM TIGR02138 YP_001694835.1 identified by match to protein family HMM PF01547; match to protein family HMM TIGR02136 YP_001694837.1 identified by match to protein family HMM PF01189 YP_001694838.1 identified by match to protein family HMM PF00459 YP_001694839.1 identified by match to protein family HMM PF05256 YP_001694840.1 the anti-alpha factor Spx interacts with RNA polymerase alpha subunit C-terminal domain in a region that interacts with the sigma 70 subunit and may interfere with activation of promoters; in Bacillus subtilis this protein is a substrate for ClpXP protease; blocks transcription of the competence regulatory gene encoded by the srf operon; regulates a number of genes involved in thiol homeostasis including trxA and trxB; monomeric member of ArsC family of proteins; does not bind DNA; contains a disulfide bond between C10 and C13 which may sense disulfide stress YP_001694841.1 identified by match to protein family HMM PF07314; match to protein family HMM TIGR01906 YP_001694842.1 identified by match to protein family HMM PF00702; match to protein family HMM TIGR01457; match to protein family HMM TIGR01460 YP_001694843.1 identified by match to protein family HMM PF01643 YP_001694844.1 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III YP_001694846.1 identified by match to protein family HMM PF06103 YP_001694847.1 transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein YP_001694848.1 catalyzes the phosphorylation of the phosphocarrier protein HPr of the bacterial phosphotransferase system YP_001694849.1 a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA YP_001694850.1 glucosamine-6-phosphate isomerase; gnpda; glcn6p deaminase; identified by match to protein family HMM PF01182 YP_001694851.1 Synthesizes oQ from preQ1 in a single S-adenosylmethionine-requiring step YP_001694852.1 identified by match to protein family HMM PF01473 YP_001694853.1 identified by match to protein family HMM PF00583 YP_001694854.1 catalyzes the formation of nicotinamide adenine dinucleotide (NAD) from nicotinic acid adenine dinucleotide (NAAD) using either ammonia or glutamine as the amide donor and ATP; ammonia-utilizing enzymes include the ones from Bacillus and Escherichia coli while glutamine-utilizing enzymes include the Mycobacterial one; forms homodimers YP_001694855.1 catalyzes the formation of 5-phospho-alpha-D-ribose 1-diphosphate and nicotinate from nicotinate D-ribonucleotide and diphosphate YP_001694857.1 identified by match to protein family HMM PF01381 YP_001694859.1 identified by match to protein family HMM PF00005 YP_001694860.1 identified by match to protein family HMM PF01136 YP_001694862.1 identified by match to protein family HMM PF01136 YP_001694863.1 identified by match to protein family HMM PF01555 YP_001694864.1 contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway YP_001694865.1 identified by match to protein family HMM PF00392; match to protein family HMM PF07702 YP_001694866.1 identified by match to protein family HMM PF00892 YP_001694867.1 identified by match to protein family HMM PF00144 YP_001694869.1 identified by match to protein family HMM PF00657 YP_001694870.1 identified by match to protein family HMM PF00702; match to protein family HMM PF05116; match to protein family HMM PF08282; match to protein family HMM TIGR00099; match to protein family HMM TIGR01484 YP_001694872.1 cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+) YP_001694873.1 identified by match to protein family HMM PF00588; match to protein family HMM PF08032; match to protein family HMM TIGR00186 YP_001694874.1 identified by match to protein family HMM PF00070; match to protein family HMM PF01134; match to protein family HMM PF03486; match to protein family HMM PF07992; match to protein family HMM TIGR01292 YP_001694876.1 identified by match to protein family HMM PF00005 YP_001694877.1 identified by match to protein family HMM PF00528; match to protein family HMM TIGR01726 YP_001694878.1 identified by match to protein family HMM PF03960; match to protein family HMM TIGR01617 YP_001694879.1 identified by match to protein family HMM PF01035; match to protein family HMM TIGR00589 YP_001694880.1 identified by match to protein family HMM PF00583 YP_001694881.1 identified by match to protein family HMM PF08876 YP_001694882.1 identified by match to protein family HMM PF03006; match to protein family HMM TIGR01065 YP_001694883.1 with PdxST is involved in the biosynthesis of pyridoxal 5'-phosphate; PdxT catalyzes the hydrolysis of glutamine to glutamate and ammonia; PdxS utilizes the ammonia to synthesize pyridoxal 5'-phosphate YP_001694884.1 with PdxT forms pyridoxal 5'-phosphate from glutamine, either ribose 5-phosphate or ribulose 5-phosphate, and either glyceraldehyde 3-phosphate or dihydroxyacetone phosphate YP_001694885.1 identified by match to protein family HMM PF00070; match to protein family HMM PF02852; match to protein family HMM PF07992 YP_001694886.1 identified by match to protein family HMM PF02424 YP_001694887.1 identified by match to protein family HMM PF03358 YP_001694888.1 identified by match to protein family HMM PF03358 YP_001694889.1 identified by match to protein family HMM PF05979 YP_001694890.1 glycine--tRNA ligase beta chain; glyS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA YP_001694891.1 glycine--tRNA ligase alpha chain; GlyRS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA YP_001694893.1 2,5-dkgreductase a; 2,5-dkgr a; 25dkgr-a; akr5c; identified by match to protein family HMM PF00248 YP_001694894.1 identified by match to protein family HMM PF01522 YP_001694896.1 identified by match to protein family HMM PF01408 YP_001694897.1 identified by match to protein family HMM PF00270; match to protein family HMM PF00271 YP_001694899.1 EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu YP_001694901.1 identified by match to protein family HMM PF00230 YP_001694902.1 identified by match to protein family HMM PF00746; match to protein family HMM PF06458; match to protein family HMM TIGR01167 YP_001694905.1 identified by match to protein family HMM PF00408; match to protein family HMM PF02878; match to protein family HMM PF02879; match to protein family HMM PF02880 YP_001694906.1 identified by match to protein family HMM TIGR01295 YP_001694907.1 identified by match to protein family HMM PF00497 YP_001694908.1 identified by match to protein family HMM PF00005 YP_001694909.1 identified by match to protein family HMM PF00528; match to protein family HMM TIGR01726 YP_001694910.1 identified by match to protein family HMM PF00515; match to protein family HMM PF07719 YP_001694911.1 identified by match to protein family HMM PF01594 YP_001694913.1 part of catalytic core of ATP synthase; alpha(3)beta(3)gamma(1)delta(1)epsilon(1); involved in producing ATP from ADP in the presence of the proton motive force across the membrane YP_001694914.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit YP_001694915.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is a regulatory subunit YP_001694916.1 produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit YP_001694917.1 Produces ATP from ADP in the presence of a proton gradient across the membrane; the delta subunit is part of the catalytic core of the ATP synthase complex YP_001694918.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit B is part of the membrane proton channel. YP_001694919.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0 YP_001694920.1 produces ATP from ADP in the presence of a proton gradient across the membrane; subunit C is part of the membrane proton channel F0 YP_001694921.1 identified by match to protein family HMM PF00665 YP_001694922.1 identified by match to protein family HMM PF00583 YP_001694923.1 identified by glimmer YP_001694924.1 Transcript cleavage factor greA; General stress protein 20M; GSP20M; necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus YP_001694925.1 identified by match to protein family HMM PF02618; match to protein family HMM TIGR00247 YP_001694926.1 identified by match to protein family HMM PF00583 YP_001694927.1 identified by match to protein family HMM PF00583 YP_001694928.1 Catalyzes the formation of UDP-N-acetylmuramoyl-L-alanine from UDP-N-acetylmuramate and L-alanine in peptidoglycan synthesis YP_001694930.1 identified by match to protein family HMM PF00176; match to protein family HMM PF00271; match to protein family HMM PF04434; match to protein family HMM PF08455 YP_001694931.1 identified by match to protein family HMM PF00155 YP_001694932.1 catalyzes the formation of cystathionine from L-cysteine and O-succinyl-L-homoserine YP_001694933.1 identified by match to protein family HMM PF00496 YP_001694934.1 identified by match to protein family HMM PF01943; match to protein family HMM PF03023 YP_001694935.1 UDP-N-acetylmuramyl-tripeptide synthetase; Meso-diaminopimelate-adding enzyme; UDP-MurNAc-tripeptide synthetase; involved in cell wall formation; peptidoglycan synthesis; cytoplasmic enzyme; catalyzes the addition of lysine to UDP-N-acetylmuramoyl-L-alanyl-D-glutamate forming UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysine YP_001694936.1 identified by match to protein family HMM PF05532 YP_001694937.1 identified by glimmer YP_001694939.1 catalyzes the hydrolysis of pyrophosphate to phosphate YP_001694940.1 identified by match to protein family HMM PF01541 YP_001694941.1 identified by match to protein family HMM PF05175 YP_001694942.1 identified by match to protein family HMM PF00575 YP_001694943.1 identified by match to protein family HMM PF00160; match to protein family HMM PF00702; match to protein family HMM PF05116; match to protein family HMM PF08282; match to protein family HMM TIGR00099; match to protein family HMM TIGR01484 YP_001694944.1 binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit YP_001694945.1 binds to single stranded DNA and may facilitate the binding and interaction of other proteins to DNA YP_001694946.1 binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21 YP_001694947.1 catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_001694948.1 identified by match to protein family HMM PF00903 YP_001694949.1 catalyzes the formation of oxalozcetate and L-glutamate from L-aspartate and 2-oxoglutarate YP_001694950.1 identified by match to protein family HMM PF03413 YP_001694951.1 identified by glimmer YP_001694952.1 identified by match to protein family HMM PF02525; match to protein family HMM PF03358 YP_001694953.1 identified by match to protein family HMM PF03883 YP_001694956.1 cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+) YP_001694957.1 YghU; B2989; one of eight glutathione transferases from E. coli YP_001694958.1 identified by match to protein family HMM PF00122; match to protein family HMM PF00689; match to protein family HMM PF00690; match to protein family HMM PF00702; match to protein family HMM TIGR01494 YP_001694959.1 identified by match to protein family HMM PF01545; match to protein family HMM TIGR01297 YP_001694960.1 identified by match to protein family HMM PF00005 YP_001694961.1 catalyzes the addition and repair of the 3'-terminal CCA sequence in tRNA; these proteins belong to the CCA-adding enzyme subfamily 2 which does not have phosphohydrolase activity YP_001694962.1 catalyzes the reduction of 2,3-dihydrodipicolinate to 2,3,4,5-tetrahydrodipicolinate in lysine and diaminopimelate biosynthesis YP_001694963.1 identified by match to protein family HMM PF02645; match to protein family HMM TIGR00762 YP_001694964.1 identified by match to protein family HMM PF06619 YP_001694965.1 catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate YP_001694966.1 identified by match to protein family HMM PF07949 YP_001694967.1 identified by match to protein family HMM PF02457; match to protein family HMM TIGR00159 YP_001694968.1 identified by match to protein family HMM PF00070; match to protein family HMM PF03486; match to protein family HMM PF07992 YP_001694969.1 identified by match to protein family HMM PF02650; match to protein family HMM TIGR00647 YP_001694970.1 identified by match to protein family HMM PF01933; match to protein family HMM TIGR01826 YP_001694971.1 identified by match to protein family HMM PF03668 YP_001694972.1 identified by match to protein family HMM PF01042; match to protein family HMM TIGR00004 YP_001694973.1 binds guanine nucleotides; in Escherichia coli depletion results in defective cell division and filamentation; in Bacillus subtilis this gene is essential YP_001694974.1 binds and unfolds substrates as part of the ClpXP protease YP_001694976.1 identified by match to protein family HMM PF00186 YP_001694977.1 identified by match to protein family HMM PF00210 YP_001694978.1 identified by glimmer YP_001694979.1 Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate YP_001694980.1 identified by match to protein family HMM PF04271; match to protein family HMM TIGR01446 YP_001694981.1 catalyzes the formation of O-succinyl-L-homoserine from succinyl-CoA and L-homoserine in methionine biosynthesis YP_001694982.1 catalyzes a salvage reaction resulting in the formation of AMP which is metabolically less costly than a de novo synthesis YP_001694983.1 identified by match to protein family HMM PF08241; match to protein family HMM PF08242 YP_001694985.1 identified by match to protein family HMM PF00005; match to protein family HMM PF03459; match to protein family HMM PF08402 YP_001694986.1 identified by match to protein family HMM PF00857 YP_001694987.1 CodY; DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase (By similarity). It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor YP_001694988.1 identified by match to protein family HMM PF00270; match to protein family HMM PF00271 YP_001694989.1 identified by match to protein family HMM PF07690 YP_001694990.1 Involved in disulfide oxidoreductase activity and electron transport YP_001694991.1 identified by match to protein family HMM PF08245; match to protein family HMM PF08353 YP_001694992.1 identified by match to protein family HMM PF07685 YP_001694993.1 X-Pro dipeptidase; Prolinedipeptidase; Prolidase; Imidodipeptidase; identified by match to protein family HMM PF00557; match to protein family HMM PF01321 YP_001694995.1 catalyzes the formation of 4-amino-2-methyl-5-diphosphomethylpyrimidine YP_001694996.1 mediates pseudouridylation (positions 38, 39, 40) at the tRNA anticodon region which contributes to the structural stability YP_001694998.1 identified by match to protein family HMM PF07690 YP_001695000.1 identified by match to protein family HMM PF03831; match to protein family HMM PF08274; match to protein family HMM TIGR00686 YP_001695001.1 Catalyzes the formation of (d)CDP from ATP and (d)CMP YP_001695004.1 identified by match to protein family HMM PF00535 YP_001695005.1 identified by match to protein family HMM PF00106; match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF02719; match to protein family HMM PF04321; match to protein family HMM PF07993; match to protein family HMM TIGR01179 YP_001695006.1 identified by match to protein family HMM PF01266 YP_001695007.1 identified by match to protein family HMM PF01784; match to protein family HMM TIGR00486 YP_001695008.1 identified by match to protein family HMM PF04816 YP_001695009.1 identified by match to protein family HMM PF00665 YP_001695010.1 catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase YP_001695011.1 identified by match to protein family HMM PF00834 YP_001695012.1 identified by match to protein family HMM PF02378; match to protein family HMM TIGR01427 YP_001695013.1 identified by match to protein family HMM PF00359; match to protein family HMM TIGR00848 YP_001695014.1 identified by match to protein family HMM PF00359 YP_001695015.1 identified by match to protein family HMM PF00874; match to protein family HMM PF05043; match to protein family HMM PF08279 YP_001695016.1 identified by match to protein family HMM PF00122; match to protein family HMM PF00702; match to protein family HMM TIGR01494 YP_001695017.1 identified by match to protein family HMM PF01553 YP_001695018.1 identified by match to protein family HMM PF03596; match to protein family HMM TIGR00779 YP_001695019.1 primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence YP_001695022.1 catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr) YP_001695023.1 identified by match to protein family HMM PF02518 YP_001695024.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00486 YP_001695027.1 identified by match to protein family HMM PF02082 YP_001695028.1 identified by match to protein family HMM PF01047; match to protein family HMM PF01325; match to protein family HMM PF02742; match to protein family HMM PF04023 YP_001695029.1 hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr); possible defense mechanism against a harmful effect of D-tyrosine YP_001695030.1 identified by match to protein family HMM PF01966; match to protein family HMM PF02824; match to protein family HMM PF04607; match to protein family HMM TIGR00691 YP_001695031.1 identified by match to protein family HMM PF00753 YP_001695032.1 identified by match to protein family HMM PF01431; match to protein family HMM PF05649 YP_001695033.1 identified by match to protein family HMM PF00005 YP_001695034.1 identified by match to protein family HMM PF00950 YP_001695035.1 identified by match to protein family HMM PF01297 YP_001695036.1 antioxidant activity; thioredoxin-dependent thiol peroxidase; forms homodimers in solution; shows substrate specificity to alkyl hydroperoxides; periplasmic protein YP_001695037.1 identified by match to protein family HMM PF02687 YP_001695038.1 identified by match to protein family HMM PF00005 YP_001695039.1 phosphoglyceromutase; pgam; bpg-dependent pgam; dpgm; 2,3-bisphosphoglycerate-dependent; catalyzes the interconversion of 2-phosphoglycerate to 3-phosphoglycerate YP_001695040.1 IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase type 1 subfamily; some organisms carry two different copies of this enzyme YP_001695042.1 identified by match to protein family HMM PF05103 YP_001695043.1 identified by match to protein family HMM PF01479 YP_001695044.1 identified by match to protein family HMM PF02325 YP_001695045.1 identified by match to protein family HMM PF04472 YP_001695046.1 identified by match to protein family HMM TIGR00044 YP_001695047.1 GTPase; similar structure to tubulin; forms ring-shaped polymers at the site of cell division; other proteins such as FtsA, ZipA, and ZapA, interact with and regulate FtsZ function YP_001695048.1 identified by match to protein family HMM PF02491; match to protein family HMM TIGR01174 YP_001695049.1 identified by match to protein family HMM TIGR02206 YP_001695050.1 identified by match to protein family HMM PF00293 YP_001695051.1 identified by match to protein family HMM PF01225; match to protein family HMM PF02875; match to protein family HMM PF08245; match to protein family HMM TIGR01143 YP_001695052.1 D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli YP_001695053.1 involved in a recombinational process of DNA repair, independent of the recBC complex YP_001695054.1 identified by match to protein family HMM PF00905; match to protein family HMM PF03717 YP_001695055.1 identified by match to protein family HMM PF01380; match to protein family HMM PF01418 YP_001695056.1 identified by match to protein family HMM PF00480 YP_001695057.1 identified by match to protein family HMM PF00701 YP_001695058.1 identified by match to protein family HMM PF04854 YP_001695060.1 identified by match to protein family HMM PF04074; match to protein family HMM TIGR00022 YP_001695061.1 identified by match to protein family HMM PF00528 YP_001695062.1 identified by match to protein family HMM PF00528 YP_001695063.1 identified by match to protein family HMM PF01547 YP_001695064.1 Converts N-acetylmannosamine-6-phosphate to N-acetylglucosamine-6-phosphate YP_001695065.1 identified by match to protein family HMM PF01118; match to protein family HMM PF01408; match to protein family HMM PF02894; match to protein family HMM PF03447 YP_001695066.1 identified by match to protein family HMM PF00528 YP_001695067.1 identified by match to protein family HMM PF00528 YP_001695068.1 identified by match to protein family HMM PF01547 YP_001695069.1 identified by match to protein family HMM PF04074; match to protein family HMM TIGR00022 YP_001695070.1 identified by match to protein family HMM PF02012; match to protein family HMM PF02973; match to protein family HMM TIGR01167 YP_001695072.1 identified by match to protein family HMM PF05448 YP_001695073.1 catalyzes branch migration in Holliday junction intermediates YP_001695074.1 converts L-alanine to D-alanine which is used in cell wall biosynthesis; binds one pyridoxal phosphate per monomer; forms a homodimer YP_001695075.1 Catalyzes the formation of holo-ACP, which mediates the essential transfer of acyl fatty acid intermediates during the biosynthesis of fatty acids and lipids YP_001695076.1 catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, phenylalanine sensitive YP_001695077.1 catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, tyrosine sensitive YP_001695078.1 functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond SecA1; SecA2 is not essential and seems to play a role in secretion of a subset of proteins YP_001695080.1 identified by match to protein family HMM PF00005 YP_001695084.1 identified by glimmer YP_001695085.1 EngA; essential Neisserial GTPase; synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains YP_001695086.1 identified by match to protein family HMM PF00881 YP_001695087.1 Primosomal protein that may act to load helicase DnaC during DNA replication YP_001695088.1 identified by match to protein family HMM PF07261 YP_001695089.1 identified by match to protein family HMM PF03477; match to protein family HMM TIGR00244 YP_001695090.1 identified by match to protein family HMM PF00392 YP_001695091.1 identified by match to protein family HMM PF00005 YP_001695094.1 identified by match to protein family HMM PF00005 YP_001695096.1 identified by match to protein family HMM PF09335 YP_001695097.1 identified by match to protein family HMM PF00480 YP_001695098.1 identified by match to protein family HMM PF00358; match to protein family HMM PF00367; match to protein family HMM PF02378; match to protein family HMM TIGR00826; match to protein family HMM TIGR00830; match to protein family HMM TIGR01996 YP_001695100.1 identified by match to protein family HMM PF00251; match to protein family HMM PF08244; match to protein family HMM TIGR01322 YP_001695101.1 identified by match to protein family HMM TIGR00532 YP_001695102.1 identified by match to protein family HMM PF01154; match to protein family HMM PF08540; match to protein family HMM TIGR01835 YP_001695104.1 identified by match to protein family HMM PF01609 YP_001695106.1 identified by match to protein family HMM PF06738 YP_001695107.1 identified by match to protein family HMM PF00069; match to protein family HMM PF01163; match to protein family HMM PF03793 YP_001695108.1 identified by match to protein family HMM PF00481 YP_001695109.1 identified by match to protein family HMM PF01029; match to protein family HMM PF01189; match to protein family HMM TIGR00563 YP_001695110.1 modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet) which is important in translation initiation; inactivation of this gene in Escherichia coli severely impairs growth YP_001695111.1 binding of PriA to forked DNA starts the assembly of the primosome, also possesses 3'-5' helicase activity YP_001695112.1 Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits YP_001695113.1 Essential for recycling GMP and indirectly, cGMP YP_001695114.1 identified by match to protein family HMM PF00013; match to protein family HMM PF01966; match to protein family HMM TIGR00277; match to protein family HMM TIGR03319 YP_001695115.1 identified by match to protein family HMM PF06769; match to protein family HMM TIGR02116 YP_001695116.1 identified by match to protein family HMM PF02604; match to protein family HMM TIGR01552 YP_001695117.1 identified by match to protein family HMM PF05636 YP_001695118.1 identified by match to protein family HMM PF08241; match to protein family HMM PF08242 YP_001695119.1 identified by match to protein family HMM PF02410; match to protein family HMM TIGR00090 YP_001695120.1 identified by match to protein family HMM PF00857 YP_001695121.1 identified by match to protein family HMM PF01966; match to protein family HMM TIGR00488 YP_001695122.1 transfers an adenyl group from ATP to NaMN to form nicotinic acid adenine dinucleotide (NaAD) which is then converted to the ubiquitous compound NAD by NAD synthetase; essential enzyme in bacteria YP_001695123.1 identified by match to protein family HMM PF01985; match to protein family HMM TIGR00253 YP_001695124.1 in Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis YP_001695125.1 identified by match to protein family HMM TIGR01662; match to protein family HMM TIGR01668 YP_001695126.1 identified by match to protein family HMM PF01544 YP_001695127.1 identified by match to protein family HMM PF00924 YP_001695128.1 identified by match to protein family HMM PF06081 YP_001695132.1 identified by match to protein family HMM TIGR02919 YP_001695133.1 identified by match to protein family HMM PF00534; match to protein family HMM PF09318; match to protein family HMM TIGR02918 YP_001695134.1 functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; in some organisms, especially gram positive pathogens, have paralogs that have been found to be nonessential but do function in secretion of a subset of exported proteins YP_001695138.1 forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase YP_001695139.1 identified by match to protein family HMM PF00535 YP_001695140.1 identified by match to protein family HMM PF01501 YP_001695141.1 identified by match to protein family HMM PF01501 YP_001695142.1 identified by match to protein family HMM PF00535 YP_001695143.1 identified by match to protein family HMM PF01501; match to protein family HMM PF08759 YP_001695145.1 identified by match to protein family HMM PF00132 YP_001695146.1 identified by match to protein family HMM PF00746; match to protein family HMM TIGR01167 YP_001695149.1 identified by match to protein family HMM PF00085; match to protein family HMM TIGR01068 YP_001695150.1 NADPH-dependent; catalyzes the reduction of 7-cyano-7-deazaguanine to 7-aminomethyl-7-deazaguanine in queuosine biosynthesis YP_001695152.1 identified by match to protein family HMM PF00230 YP_001695154.1 identified by glimmer YP_001695155.1 identified by match to protein family HMM PF01432; match to protein family HMM PF08439; match to protein family HMM TIGR00181 YP_001695156.1 in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA; cells lacking this function can grow, but are outcompeted by wild-type; SAM-dependent m(3)U1498 methyltransferase YP_001695157.1 methylates ribosomal protein L11 at multiple amino acid positions; mutations of these genes in Escherichia coli or Thermus thermophilus has no apparent phenotype YP_001695158.1 identified by match to protein family HMM PF00293 YP_001695159.1 identified by match to protein family HMM PF02163 YP_001695161.1 identified by match to protein family HMM PF03681 YP_001695162.1 identified by match to protein family HMM PF07927 YP_001695164.1 identified by match to protein family HMM PF00004 YP_001695165.1 identified by match to protein family HMM PF00251; match to protein family HMM TIGR01322 YP_001695166.1 identified by match to protein family HMM PF00528 YP_001695167.1 identified by match to protein family HMM PF00528 YP_001695168.1 identified by match to protein family HMM PF01547 YP_001695169.1 identified by match to protein family HMM PF00356; match to protein family HMM PF00532 YP_001695170.1 identified by match to protein family HMM PF05043; match to protein family HMM PF08270; match to protein family HMM PF08279; match to protein family HMM PF08280 YP_001695173.1 identified by match to protein family HMM PF03780 YP_001695174.1 identified by match to protein family HMM PF05532 YP_001695176.1 identified by glimmer YP_001695177.1 identified by match to protein family HMM PF01925 YP_001695178.1 identified by match to protein family HMM PF03781 YP_001695179.1 can hydrolyze p-nitrophenyl sulfate; contains a specific cysteine that is converted into C{alpha]-formylglycine upon activation with the anaerobic sulfatase-maturase YP_001695180.1 identified by match to protein family HMM PF02378; match to protein family HMM TIGR00410 YP_001695181.1 pts system lichenan-specific eiia component; eiia-lic; eiii-lic; identified by match to protein family HMM PF02255 YP_001695182.1 pts system lichenan-specific eiib component; eiib-lic; identified by match to protein family HMM PF02302 YP_001695184.1 pts system lichenan-specific eiiccomponent; eiic-lic; identified by match to protein family HMM PF02378; match to protein family HMM TIGR00410 YP_001695185.1 identified by match to protein family HMM PF00480 YP_001695186.1 identified by match to protein family HMM PF00583 YP_001695187.1 identified by match to protein family HMM PF01478; match to protein family HMM PF06750 YP_001695188.1 catalyzes the formation of indole and glyceraldehyde 3-phosphate from indoleglycerol phosphate in tryptophan biosynthesis YP_001695189.1 catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate YP_001695190.1 catalyzes the formation of 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate from N-(5-phospho-beta-D-ribosyl)-anthranilate in tryptophan biosynthesis YP_001695191.1 involved in tryptophan biosynthesis; amino acid biosynthesis; converts 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate to C(1)-(3-indolyl)-glycerol 3-phosphate and carbon dioxide and water YP_001695192.1 Catalyzes the conversion of N-(5-phospho-D-ribosyl)-anthranilate and diphosphate to anthranilate and 5-phospho-alpha-D-ribose 1-diphosphate YP_001695193.1 TrpG; with TrpE catalyzes the formation of anthranilate and glutamate from chorismate and glutamine; TrpG provides the glutamine amidotransferase activity YP_001695194.1 with component II, the glutamine amidotransferase, catalyzes the formation of anthranilate from chorismate and glutamine YP_001695196.1 identified by match to protein family HMM PF00356; match to protein family HMM PF00532 YP_001695198.1 identified by match to protein family HMM PF02308 YP_001695199.1 identified by match to protein family HMM PF00528 YP_001695200.1 identified by match to protein family HMM PF00005; match to protein family HMM PF03459; match to protein family HMM PF08402 YP_001695202.1 identified by match to protein family HMM PF08975 YP_001695205.1 identified by match to protein family HMM PF04650; match to protein family HMM TIGR01168 YP_001695207.1 identified by match to protein family HMM PF01041 YP_001695208.1 identified by match to protein family HMM PF02397 YP_001695209.1 identified by match to protein family HMM PF00005; match to protein family HMM PF00664 YP_001695210.1 identified by match to protein family HMM PF00005; match to protein family HMM PF00664 YP_001695211.1 identified by match to protein family HMM PF04239 YP_001695212.1 identified by match to protein family HMM PF03372; match to protein family HMM TIGR00195; match to protein family HMM TIGR00633 YP_001695213.1 Catalyzes the transfer of the phosphoribosyl moiety from 5-phospho--D-ribosyl-1-pyrophosphate (PRib-PP) to the 6-oxo-guanine and -xanthine YP_001695214.1 identified by match to protein family HMM PF00860; match to protein family HMM PF00916; match to protein family HMM TIGR00801; match to protein family HMM TIGR03173 YP_001695215.1 identified by match to protein family HMM PF04556 YP_001695216.1 identified by match to protein family HMM PF01555 YP_001695217.1 identified by match to protein family HMM PF02086; match to protein family HMM TIGR00571 YP_001695218.1 identified by match to protein family HMM PF03061; match to protein family HMM TIGR00369 YP_001695219.1 catalyzes the formation of alpha-D-glucose 1-phosphate and UDP-galactose from UDP-glucose and alpha-D-galactose 1-phosphate in galactose metabolism YP_001695220.1 catalyzes the formation of alpha-D-galactose 1-phosphate from D-galactose in galactose metabolism YP_001695221.1 member of GalR-LacI family of transcriptional regulators, binds DNA; regulator of gal operon; identified by match to protein family HMM PF00356; match to protein family HMM PF00532 YP_001695222.1 identified by match to protein family HMM PF00107; match to protein family HMM PF08240 YP_001695223.1 identified by match to protein family HMM PF00376 YP_001695224.1 identified by match to protein family HMM PF01545; match to protein family HMM TIGR01297 YP_001695225.1 identified by match to protein family HMM PF00440 YP_001695226.1 identified by match to protein family HMM PF04973; match to protein family HMM TIGR01528 YP_001695227.1 identified by glimmer YP_001695228.1 identified by match to protein family HMM PF00528; match to protein family HMM PF04069 YP_001695229.1 identified by match to protein family HMM PF00005 YP_001695230.1 identified by match to protein family HMM PF07366 YP_001695231.1 identified by match to protein family HMM PF01047 YP_001695233.1 identified by match to protein family HMM PF05343; match to protein family HMM TIGR03107 YP_001695235.1 identified by match to protein family HMM PF01032 YP_001695236.1 identified by match to protein family HMM PF01032 YP_001695237.1 identified by match to protein family HMM PF00005 YP_001695238.1 identified by match to protein family HMM PF01497 YP_001695239.1 identified by match to protein family HMM PF01809; match to protein family HMM TIGR00278 YP_001695240.1 identified by match to protein family HMM PF00849; match to protein family HMM PF01479; match to protein family HMM TIGR00093 YP_001695241.1 functions during chromosome segregation; may form a condensin-like structure with SMC and ScpA; forms a homodimer YP_001695242.1 functions during chromosome segregation; may form a condensin-like structure with SMC and ScpB YP_001695243.1 site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs YP_001695244.1 identified by match to protein family HMM PF00571 YP_001695245.1 identified by match to protein family HMM PF00149; match to protein family HMM TIGR00040 YP_001695246.1 HAM1-like protein; Rec-dependent growth; RgdB; yggV; it is suspected that this protein functions to remove misincorporated bases such as xanthine or hypoxanthine YP_001695247.1 converts L-glutamate to D-glutamate, a component of peptidoglycan YP_001695248.1 identified by match to protein family HMM PF03672 YP_001695249.1 identified by match to protein family HMM PF00128; match to protein family HMM TIGR02403 YP_001695250.1 identified by match to protein family HMM PF00358; match to protein family HMM PF00367; match to protein family HMM PF02378; match to protein family HMM TIGR00826; match to protein family HMM TIGR00830; match to protein family HMM TIGR01992 YP_001695251.1 identified by match to protein family HMM PF00392; match to protein family HMM PF07702; match to protein family HMM TIGR02404 YP_001695252.1 identified by match to protein family HMM PF00005; match to protein family HMM PF08352 YP_001695253.1 identified by match to protein family HMM PF00005; match to protein family HMM PF08352; match to protein family HMM TIGR01727 YP_001695254.1 identified by match to protein family HMM PF00528 YP_001695255.1 identified by match to protein family HMM PF00528 YP_001695256.1 identified by match to protein family HMM PF00496 YP_001695257.1 identified by match to protein family HMM PF04932 YP_001695258.1 identified by match to protein family HMM PF00128 YP_001695259.1 identified by match to protein family HMM PF00528 YP_001695260.1 identified by match to protein family HMM PF00528 YP_001695261.1 identified by match to protein family HMM PF01547 YP_001695262.1 identified by match to protein family HMM PF02065 YP_001695263.1 identified by match to protein family HMM PF00165; match to protein family HMM PF02311 YP_001695264.1 catalyzes the formation of biotinyl-5'-AMP, also acts as a transcriptional repressor of the biotin operon YP_001695265.1 binds RecA and inhibits RecA-mediated DNA strand exchange and ATP hydrolysis and coprotease activities YP_001695266.1 identified by match to protein family HMM PF04167 YP_001695268.1 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth YP_001695269.1 10 kDa chaperonin; Cpn10; GroES; forms homoheptameric ring; binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it; folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES; release of the folded substrate is dependent on ATP binding and hydrolysis in the trans ring YP_001695270.1 binds to single stranded DNA and may facilitate the binding and interaction of other proteins to DNA YP_001695271.1 identified by match to protein family HMM PF00106; match to protein family HMM PF08659 YP_001695272.1 identified by match to protein family HMM PF01588 YP_001695273.1 identified by match to protein family HMM PF00085 YP_001695276.1 identified by match to protein family HMM PF04397 YP_001695277.1 identified by match to protein family HMM PF01569 YP_001695279.1 identified by match to protein family HMM PF01047 YP_001695280.1 identified by match to protein family HMM PF01709; match to protein family HMM TIGR01033 YP_001695281.1 identified by match to protein family HMM PF01289 YP_001695286.1 identified by glimmer YP_001695288.1 identified by match to protein family HMM PF00005 YP_001695289.1 identified by match to protein family HMM PF00528 YP_001695290.1 identified by match to protein family HMM PF02308 YP_001695291.1 identified by match to protein family HMM PF00702; match to protein family HMM TIGR01509 YP_001695292.1 identified by match to protein family HMM PF00356 YP_001695293.1 identified by match to protein family HMM PF01609 YP_001695300.1 N-acetylmuramoyl-L-alanine amidase; Mureinhydrolase; Mucopeptide aminohydrolase; Cell wall hydrolase; identified by match to protein family HMM PF01473 YP_001695301.1 identified by match to protein family HMM PF01554; match to protein family HMM TIGR00797 YP_001695302.1 catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs YP_001695303.1 identified by match to protein family HMM PF00994; match to protein family HMM PF02464; match to protein family HMM TIGR00199; match to protein family HMM TIGR00200 YP_001695304.1 identified by match to protein family HMM PF03816; match to protein family HMM TIGR00350 YP_001695305.1 identified by match to protein family HMM PF00583 YP_001695306.1 identified by match to protein family HMM PF02367; match to protein family HMM TIGR00150 YP_001695308.1 identified by match to protein family HMM PF01381 YP_001695310.1 identified by match to protein family HMM PF07242; match to protein family HMM TIGR01654 YP_001695311.1 identified by match to protein family HMM PF00005 YP_001695313.1 NDK; NDP kinase; Abnormal wing disks protein; Killer of prune protein; catalyzes the formation of nucleoside triphosphate from ATP and nucleoside diphosphate YP_001695314.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Subunit beta' binds to sigma factor allowing it to bind to the -10 region of the promoter YP_001695315.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme YP_001695316.1 identified by glimmer YP_001695317.1 identified by match to protein family HMM PF00571; match to protein family HMM PF01595; match to protein family HMM PF03471 YP_001695318.1 identified by match to protein family HMM PF01223 YP_001695320.1 adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active YP_001695321.1 identified by match to protein family HMM TIGR02327 YP_001695323.1 Catalyzes the conversion of ATP and pantetheine 4'-phosphate to diphosphate and 3'-dephospho-coA YP_001695324.1 identified by match to protein family HMM PF03602; match to protein family HMM TIGR00095 YP_001695325.1 catalyzes the formation of asparagine from aspartate and ammonia YP_001695326.1 identified by match to protein family HMM PF01027 YP_001695327.1 identified by match to protein family HMM PF00588; match to protein family HMM PF08032 YP_001695328.1 catalyzes the hydrolysis of acylphosphate YP_001695329.1 involved in biogenesis of membrane proteins; Firmicutes specific proteins are shorter than other bacterial counterparts and have a signal peptide and lipid attachment site YP_001695330.1 identified by match to protein family HMM PF04055; match to protein family HMM TIGR02493 YP_001695331.1 identified by match to protein family HMM PF00278; match to protein family HMM PF02784 YP_001695332.1 identified by match to protein family HMM PF00156; match to protein family HMM PF09182; match to protein family HMM TIGR01743 YP_001695333.1 identified by match to protein family HMM PF01336; match to protein family HMM PF01966 YP_001695334.1 identified by match to protein family HMM PF02646 YP_001695335.1 identified by match to protein family HMM PF04263; match to protein family HMM PF04265; match to protein family HMM TIGR01378 YP_001695336.1 identified by match to protein family HMM PF00834; match to protein family HMM TIGR01163 YP_001695337.1 EngC; RsgA; CpgA; circularly permuted GTPase; ribosome small subunit-dependent GTPase A; has the pattern G4-G1-G3 as opposed to other GTPases; interacts strongly with 30S ribosome which stimulates GTPase activity YP_001695338.1 catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin YP_001695340.1 identified by match to protein family HMM PF00005 YP_001695341.1 identified by match to protein family HMM PF07242; match to protein family HMM TIGR01654 YP_001695342.1 identified by match to protein family HMM TIGR01653 YP_001695343.1 identified by match to protein family HMM PF01381 YP_001695344.1 identified by match to protein family HMM PF01751; match to protein family HMM TIGR00334 YP_001695345.1 identified by match to protein family HMM PF01026; match to protein family HMM TIGR00010 YP_001695346.1 identified by match to protein family HMM PF00746; match to protein family HMM PF07564; match to protein family HMM TIGR01167 YP_001695347.1 in Escherichia coli transcription of this gene is enhanced by polyamines YP_001695348.1 broad specificity; family IV; in Corynebacterium glutamicum this protein can use glutamate, 2-aminobutyrate, and aspartate as amino donors and pyruvate as the acceptor YP_001695350.1 identified by match to protein family HMM PF00582 YP_001695351.1 identified by match to protein family HMM PF05116; match to protein family HMM PF08282; match to protein family HMM TIGR00099 YP_001695352.1 identified by match to protein family HMM PF00710 YP_001695354.1 identified by match to protein family HMM PF00356; match to protein family HMM PF00532; match to protein family HMM TIGR01481 YP_001695355.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00196 YP_001695356.1 identified by match to protein family HMM PF02518; match to protein family HMM PF07730 YP_001695357.1 identified by match to protein family HMM PF01061 YP_001695358.1 identified by match to protein family HMM PF00005 YP_001695362.1 Modulates Rho-dependent transcription termination YP_001695363.1 forms a complex with SecY and SecG; SecYEG forms a protein-conducting channel to which secA binds and translocates targeted polypeptides across the cytoplasmic membrane, a process driven by ATP and a proton-motive force YP_001695364.1 identified by match to protein family HMM PF00905; match to protein family HMM PF00912; match to protein family HMM TIGR02074 YP_001695365.1 identified by match to protein family HMM PF00849 YP_001695366.1 identified by match to protein family HMM PF00044; match to protein family HMM PF02800; match to protein family HMM TIGR01534 YP_001695367.1 identified by match to protein family HMM PF02687 YP_001695368.1 identified by match to protein family HMM PF01710 YP_001695369.1 catalyzes the formation of pyridine-2,3-dicarboxylate and 5-phospho-alpha-D-ribose 1-diphosphate from nictinate D-ribonucleotide YP_001695370.1 identified by match to protein family HMM PF03600; match to protein family HMM PF07158 YP_001695372.1 identified by match to protein family HMM PF00392; match to protein family HMM PF07702 YP_001695373.1 identified by match to protein family HMM PF00232 YP_001695374.1 identified by match to protein family HMM PF02378; match to protein family HMM TIGR00410 YP_001695375.1 pts system lichenan-specific eiib component; eiib-lic; identified by match to protein family HMM PF02302 YP_001695376.1 pts system lichenan-specific eiia component; eiia-lic; eiii-lic; identified by match to protein family HMM PF02255 YP_001695377.1 identified by match to protein family HMM PF00465 YP_001695378.1 identified by match to protein family HMM PF02493 YP_001695379.1 identified by match to protein family HMM PF01451 YP_001695380.1 member of preprotein translocase; forms a heterotrimer with SecD and SecF; links the SecD/SecF/YajC/YidC complex with the SecY/SecE/SecG complex YP_001695381.1 catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase YP_001695383.1 identified by match to protein family HMM PF00874; match to protein family HMM PF08279 YP_001695384.1 catalyzes the formation of D-xylulose 5-phosphate from L-ribulose 5-phosphate in the L-arabinose and L-ascorbate degradation pathways YP_001695385.1 L-xylulose 5-phosphate 3-epimerase activity not yet demonstrated; may be involved in the utilization of 2,3-diketo-L-gulonate YP_001695386.1 catalyzes the formation of L-xylulose-5-phosphate from 3-keto-L-gulonate-6-phosphate in anaerobic L-ascorbate utilization YP_001695387.1 identified by match to protein family HMM PF00359 YP_001695388.1 identified by match to protein family HMM PF02302 YP_001695389.1 membrane component; functions with enzymes IIB (sgaB; ulaB) and IIA (sgaA; ulaC) enzyme I and HPr for anaerobic utilization and uptake of L-ascorbate; sgaTBA are regulated by yifQ as well as Crp and Fnr YP_001695391.1 identified by match to protein family HMM PF01424 YP_001695392.1 identified by match to protein family HMM PF02096 YP_001695393.1 protein component of RNaseP which catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'terminus; this enzyme also cleaves other RNA substrates YP_001695395.1 AckA utilizes acetate and can acetylate CheY which increases signal strength during flagellar rotation; utilizes magnesium and ATP; also involved in conversion of acetate to aceyl-CoA YP_001695402.1 identified by match to protein family HMM PF07963; match to protein family HMM TIGR02532 YP_001695403.1 identified by match to protein family HMM PF00482 YP_001695404.1 identified by match to protein family HMM PF00437 YP_001695405.1 identified by match to protein family HMM PF06279 YP_001695406.1 identified by match to protein family HMM PF00107; match to protein family HMM PF08240 YP_001695407.1 identified by match to protein family HMM PF01979; match to protein family HMM TIGR00221 YP_001695408.1 identified by match to protein family HMM PF01757 YP_001695409.1 Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr) YP_001695411.1 identified by match to protein family HMM PF01476 YP_001695412.1 identified by match to protein family HMM PF00702; match to protein family HMM TIGR01549 YP_001695413.1 identified by match to protein family HMM PF01554; match to protein family HMM PF03023; match to protein family HMM TIGR00797 YP_001695414.1 catalyzes the formation of L-threonine from O-phospho-L-homoserine YP_001695416.1 identified by glimmer YP_001695417.1 identified by glimmer YP_001695418.1 identified by glimmer YP_001695419.1 identified by match to protein family HMM PF03372 YP_001695420.1 identified by match to protein family HMM PF01580 YP_001695423.1 identified by match to protein family HMM PF00149 YP_001695426.1 identified by match to protein family HMM PF00589 YP_001695428.1 identified by match to protein family HMM PF01402 YP_001695429.1 identified by match to protein family HMM PF00149 YP_001695430.1 identified by match to protein family HMM PF01610 YP_001695432.1 Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation YP_001695433.1 functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis; catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate; member of PGI family YP_001695435.1 identified by match to protein family HMM PF00117; match to protein family HMM PF07722 YP_001695436.1 identified by match to protein family HMM PF00005; match to protein family HMM PF00664 YP_001695437.1 identified by glimmer YP_001695439.1 identified by match to protein family HMM PF00005; match to protein family HMM PF00664 YP_001695440.1 This protein performs the mismatch recognition step during the DNA repair process YP_001695441.1 identified by match to protein family HMM PF01316; match to protein family HMM PF02863; match to protein family HMM TIGR01529 YP_001695442.1 catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase YP_001695443.1 identified by match to protein family HMM PF01609 YP_001695444.1 identified by match to protein family HMM PF06172 YP_001695445.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00486 YP_001695446.1 identified by match to protein family HMM PF00512; match to protein family HMM PF02518 YP_001695448.1 identified by match to protein family HMM PF00528; match to protein family HMM TIGR02138 YP_001695449.1 identified by match to protein family HMM PF00528; match to protein family HMM TIGR00974 YP_001695450.1 ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation YP_001695451.1 identified by match to protein family HMM PF01895; match to protein family HMM TIGR02135 YP_001695453.1 NAD(P)H-dependent glycerol-3-phosphate dehydrogenase; NAD(P)H-dependentdihydroxyacetone-phosphate reductase; catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate YP_001695454.1 identified by match to protein family HMM PF00483; match to protein family HMM TIGR01099 YP_001695455.1 identified by match to protein family HMM PF01694 YP_001695456.1 identified by match to protein family HMM PF01812; match to protein family HMM TIGR02727 YP_001695457.1 identified by match to protein family HMM PF01546; match to protein family HMM PF07687; match to protein family HMM TIGR01891 YP_001695458.1 identified by match to protein family HMM PF00132; match to protein family HMM PF08503 YP_001695459.1 identified by match to protein family HMM PF00892 YP_001695460.1 identified by match to protein family HMM PF00905; match to protein family HMM PF00912 YP_001695461.1 catalyzes the formation of tyrosyl-tRNA(Tyr) from tyrosine and tRNA(Tyr) YP_001695462.1 identified by match to protein family HMM PF00122; match to protein family HMM PF00702; match to protein family HMM TIGR01494; match to protein family HMM TIGR01525 YP_001695464.1 identified by match to protein family HMM PF08241 YP_001695465.1 identified by glimmer YP_001695466.1 identified by match to protein family HMM PF00343; match to protein family HMM TIGR02093 YP_001695467.1 amylomaltase; acts to release glucose from maltodextrins YP_001695468.1 identified by match to protein family HMM PF01547 YP_001695469.1 identified by match to protein family HMM PF00528; match to protein family HMM PF05154 YP_001695470.1 identified by match to protein family HMM PF00528 YP_001695472.1 identified by match to protein family HMM PF00356; match to protein family HMM PF00532 YP_001695473.1 identified by match to protein family HMM PF02588 YP_001695474.1 catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes YP_001695476.1 identified by match to protein family HMM PF02517 YP_001695479.1 identified by match to protein family HMM PF01381 YP_001695482.1 catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG YP_001695484.1 identified by match to protein family HMM TIGR01716 YP_001695486.1 identified by match to protein family HMM PF01883 YP_001695487.1 catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis YP_001695488.1 identified by match to protein family HMM PF02779; match to protein family HMM PF02780 YP_001695489.1 identified by match to protein family HMM PF00456 YP_001695490.1 membrane component; functions with enzymes IIB (sgaB; ulaB) and IIA (sgaA; ulaC) enzyme I and HPr for anaerobic utilization and uptake of L-ascorbate; sgaTBA are regulated by yifQ as well as Crp and Fnr YP_001695491.1 identified by match to protein family HMM PF02302 YP_001695492.1 identified by match to protein family HMM PF00359; match to protein family HMM PF00874 YP_001695493.1 identified by match to protein family HMM PF01145 YP_001695495.1 some L32 proteins have zinc finger motifs consisting of CXXC while others do not YP_001695496.1 in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif YP_001695497.1 identified by match to protein family HMM PF01473 YP_001695499.1 identified by match to protein family HMM PF00728 YP_001695500.1 identified by match to protein family HMM PF00480 YP_001695501.1 identified by match to protein family HMM PF01074; match to protein family HMM PF07748 YP_001695502.1 identified by match to protein family HMM PF06824 YP_001695503.1 identified by match to protein family HMM PF07971; match to protein family HMM TIGR01180 YP_001695505.1 catalyzes the degradation of arginine to citruline and ammonia YP_001695506.1 catalyzes the formation of ornithine and carbamylphosphate from citrulline in the arginine catabolic pathway YP_001695507.1 catalyzes the reversible synthesis of carbamate and ATP from carbamoyl phosphate and ADP YP_001695508.1 identified by match to protein family HMM PF03606 YP_001695509.1 identified by match to protein family HMM PF01546; match to protein family HMM TIGR01887 YP_001695510.1 identified by match to protein family HMM PF04650; match to protein family HMM TIGR01168 YP_001695511.1 identified by match to protein family HMM PF01145 YP_001695512.1 identified by match to protein family HMM PF00465 YP_001695513.1 catalyzes the conversion of the aldose L-fucose into the corresponding ketose L-fuculose YP_001695514.1 identified by match to protein family HMM PF00754; match to protein family HMM PF08306; match to protein family HMM PF08307 YP_001695516.1 pts system mannose-specific eiidcomponent; eiid-man; eii-m-man; identified by match to protein family HMM PF03613 YP_001695517.1 identified by match to protein family HMM PF03609 YP_001695518.1 identified by match to protein family HMM PF03830 YP_001695519.1 identified by match to protein family HMM PF03610 YP_001695520.1 identified by match to protein family HMM PF05025 YP_001695521.1 catalyzes the formation of glycerone phosphate and (S)-lactaldehyde from L-fuculose 1-phosphate YP_001695522.1 identified by match to protein family HMM PF00370; match to protein family HMM PF02782 YP_001695523.1 identified by match to protein family HMM PF00455; match to protein family HMM PF08220; match to protein family HMM PF08279 YP_001695524.1 identified by glimmer YP_001695525.1 identified by match to protein family HMM PF01297; match to protein family HMM PF09223 YP_001695526.1 identified by match to protein family HMM PF00950 YP_001695527.1 identified by match to protein family HMM PF00005 YP_001695528.1 identified by match to protein family HMM PF01022; match to protein family HMM PF01047; match to protein family HMM PF01325; match to protein family HMM PF01978; match to protein family HMM PF08279 YP_001695530.1 identified by match to protein family HMM PF04914; match to protein family HMM PF04915; match to protein family HMM PF04918 YP_001695531.1 D-alanyl carrier protein subunit; involved in the incorporation of D-alanine into membrane-associated D-alanyl-lipoteichoic acid; D-alanyl carrier protein is the acceptor of activated D-alanine which it donates to a membrane acceptor(D-alanyl transferase) for incorporation into membrane lipoteichoic acid YP_001695532.1 identified by match to protein family HMM PF03062 YP_001695533.1 transfers D-alanine to the D-alanyl carrier protein during the incorporation of D-alanine into lipoteichoic acid YP_001695536.1 identified by match to protein family HMM PF00078; match to protein family HMM PF08388 YP_001695538.1 identified by glimmer YP_001695539.1 identified by match to protein family HMM PF00230; match to protein family HMM TIGR00861 YP_001695540.1 identified by match to protein family HMM PF01266 YP_001695541.1 Converts glycerol and ADP to glycerol-3-phosphate and ADP YP_001695542.1 identified by match to protein family HMM PF05043 YP_001695543.1 becomes active under oxidative stress; four conserved cysteines bind a zinc atom when they are in the reduced state and the enzyme is inactive; oxidative stress results in oxidized cysteines, release of zinc, and binding of Hsp33 to aggregation-prone proteins; forms dimers and higher order oligomers YP_001695544.1 identified by match to protein family HMM PF00724; match to protein family HMM PF01180; match to protein family HMM PF01207; match to protein family HMM TIGR00737 YP_001695545.1 identified by match to protein family HMM PF00746; match to protein family HMM PF05062; match to protein family HMM TIGR01167 YP_001695546.1 identified by match to protein family HMM PF01610 YP_001695547.1 identified by match to protein family HMM PF01473; match to protein family HMM PF04650; match to protein family HMM PF05062; match to protein family HMM TIGR01168 YP_001695548.1 identified by match to protein family HMM PF04140 YP_001695549.1 identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518 YP_001695550.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00486 YP_001695551.1 identified by glimmer YP_001695552.1 identified by match to protein family HMM PF00004; match to protein family HMM PF02861; match to protein family HMM PF07724; match to protein family HMM PF07728 YP_001695553.1 identified by match to protein family HMM PF05848 YP_001695554.1 identified by match to protein family HMM PF00005 YP_001695555.1 identified by match to protein family HMM PF09084 YP_001695556.1 identified by match to protein family HMM PF00528 YP_001695558.1 identified by match to protein family HMM PF01473; match to protein family HMM PF05257; match to protein family HMM PF08460 YP_001695559.1 identified by match to protein family HMM PF06257 YP_001695560.1 unwinds double stranded DNA YP_001695561.1 in Escherichia coli this protein is wrapped around the base of the L1 stalk YP_001695562.1 identified by match to protein family HMM PF02482; match to protein family HMM TIGR00741 YP_001695564.1 identified by match to protein family HMM PF00271; match to protein family HMM PF04851 YP_001695565.1 identified by match to protein family HMM PF01205; match to protein family HMM TIGR00257 YP_001695566.1 identified by match to protein family HMM PF00291; match to protein family HMM TIGR01136; match to protein family HMM TIGR01139 YP_001695567.1 EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu YP_001695568.1 one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit YP_001695569.1 identified by match to protein family HMM PF05257 YP_001695570.1 identified by match to protein family HMM PF04093; match to protein family HMM TIGR03426 YP_001695571.1 in some organisms this protein is a transmembrane protein while in others it is periplasmic; involved in some organisms with other components of the MreBCD complex and with penicillin binding proteins in the periplasm or cell wall YP_001695572.1 identified by match to protein family HMM PF02361 YP_001695573.1 with CbiNQ forms the ABC transporter for cobalt import; Streptococcus has two adjacent copies of this gene YP_001695574.1 identified by match to protein family HMM PF01066; match to protein family HMM TIGR00560 YP_001695576.1 identified by match to protein family HMM PF00675; match to protein family HMM PF05193 YP_001695577.1 identified by match to protein family HMM PF05193 YP_001695578.1 identified by match to protein family HMM TIGR02988 YP_001695579.1 Required for DNA replication; binds preferentially to single-stranded, linear DNA YP_001695580.1 catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate YP_001695581.1 catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_001695582.1 identified by match to protein family HMM PF00005 YP_001695584.1 identified by match to protein family HMM PF00440 YP_001695585.1 identified by match to protein family HMM PF00072; match to protein family HMM PF04397 YP_001695586.1 identified by match to protein family HMM PF02518 YP_001695587.1 identified by match to protein family HMM PF03047 YP_001695588.1 identified by match to protein family HMM PF00089 YP_001695589.1 identified by match to protein family HMM PF02195; match to protein family HMM TIGR00180