-- dump date 20140620_084901 -- class Genbank::CDS -- table cds -- table main -- field 1 id -- field 2 GI -- field 3 GeneID -- field 4 chrom_position -- field 5 chromosome -- field 6 codon_start -- field 7 contig -- field 8 description -- field 9 end_pos -- field 10 gene -- field 11 gene_id -- field 12 name -- field 13 organism -- field 14 product -- field 15 protein_id -- field 16 start_pos -- field 17 strand -- field 18 taxid -- field 19 type -- header -- id GI GeneID chrom_position chromosome codon_start contig description end_pos gene gene_id name organism product protein_id start_pos strand taxid type YP_002737247.1 225855736 7680774 197..1558 1 NC_012467.1 binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication; can also affect transcription of multiple genes including itself.; chromosomal replication initiation protein 1558 dnaA 7680774 dnaA Streptococcus pneumoniae P1031 chromosomal replication initiation protein YP_002737247.1 197 D 488223 CDS YP_002737248.1 225855737 7681661 1717..2853 1 NC_012467.1 binds the polymerase to DNA and acts as a sliding clamp; DNA polymerase III subunit beta 2853 dnaN 7681661 dnaN Streptococcus pneumoniae P1031 DNA polymerase III subunit beta YP_002737248.1 1717 D 488223 CDS YP_002737249.1 225855738 7681640 2918..3112 1 NC_012467.1 identified by match to protein family HMM PF06107; hypothetical protein 3112 7681640 SPP_0003 Streptococcus pneumoniae P1031 hypothetical protein YP_002737249.1 2918 D 488223 CDS YP_002737250.1 225855739 7681839 3196..4311 1 NC_012467.1 translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1; GTP-dependent nucleic acid-binding protein EngD 4311 ychF 7681839 ychF Streptococcus pneumoniae P1031 GTP-dependent nucleic acid-binding protein EngD YP_002737250.1 3196 D 488223 CDS YP_002737251.1 225855740 7680775 4382..4951 1 NC_012467.1 Enables the recycling of peptidyl-tRNAs produced at termination of translation; peptidyl-tRNA hydrolase 4951 pth 7680775 pth Streptococcus pneumoniae P1031 peptidyl-tRNA hydrolase YP_002737251.1 4382 D 488223 CDS YP_002737252.1 225855741 7681404 4952..8461 1 NC_012467.1 identified by match to protein family HMM PF00270; match to protein family HMM PF00271; match to protein family HMM PF02559; match to protein family HMM PF03461; match to protein family HMM PF04851; match to protein family HMM TIGR00580; transcription-repair coupling factor 8461 mfd 7681404 mfd Streptococcus pneumoniae P1031 transcription-repair coupling factor YP_002737252.1 4952 D 488223 CDS YP_002737253.1 225855742 7682584 8519..8785 1 NC_012467.1 identified by match to protein family HMM PF01479; ribosome-associated heat shock protein implicated in the recycling of the 50S subunit 8785 7682584 SPP_0007 Streptococcus pneumoniae P1031 ribosome-associated heat shock protein implicated in the recycling of the 50S subunit YP_002737253.1 8519 D 488223 CDS YP_002737254.1 225855743 7682001 8778..9146 1 NC_012467.1 identified by match to protein family HMM PF04977; septum formation initiator 9146 7682001 SPP_0008 Streptococcus pneumoniae P1031 septum formation initiator YP_002737254.1 8778 D 488223 CDS YP_002737255.1 225855744 7682200 9151..9273 1 NC_012467.1 hypothetical protein 9273 7682200 SPP_0009 Streptococcus pneumoniae P1031 hypothetical protein YP_002737255.1 9151 D 488223 CDS YP_002737256.1 225855745 7681580 9266..10534 1 NC_012467.1 beta-lactamase class A 10534 7681580 SPP_0010 Streptococcus pneumoniae P1031 beta-lactamase class A YP_002737256.1 9266 D 488223 CDS YP_002737257.1 225855746 7681887 10531..11808 1 NC_012467.1 identified by match to protein family HMM PF01171; match to protein family HMM TIGR02432; match to protein family HMM TIGR02433; tRNA(Ile)-lysidine synthase (tRNA(Ile)-lysidinesynthetase) (tRNA(Ile)-2-lysyl-cytidine synthase) 11808 7681887 SPP_0011 Streptococcus pneumoniae P1031 tRNA(Ile)-lysidine synthase (tRNA(Ile)-lysidinesynthetase) (tRNA(Ile)-2-lysyl-cytidine synthase) YP_002737257.1 10531 D 488223 CDS YP_002737258.1 225855747 7681100 11812..12354 1 NC_012467.1 identified by match to protein family HMM PF00156; match to protein family HMM TIGR01203; hypoxanthine phosphoribosyltransferase 12354 hpt 7681100 hpt Streptococcus pneumoniae P1031 hypoxanthine phosphoribosyltransferase YP_002737258.1 11812 D 488223 CDS YP_002737259.1 225855748 7681019 12370..14328 1 NC_012467.1 identified by match to protein family HMM PF00004; match to protein family HMM PF01434; match to protein family HMM PF06480; match to protein family HMM TIGR01241; ATP-dependent metallopeptidase HflB 14328 hflB 7681019 hflB Streptococcus pneumoniae P1031 ATP-dependent metallopeptidase HflB YP_002737259.1 12370 D 488223 CDS YP_002737260.1 225855749 7682022 14450..14929 1 NC_012467.1 competence-specific global transcription modulator 14929 7682022 SPP_0014 Streptococcus pneumoniae P1031 competence-specific global transcription modulator YP_002737260.1 14450 D 488223 CDS YP_002737261.1 225855750 7680750 20422..20751 1 NC_012467.1 identified by match to protein family HMM PF01710; transposase 20751 7680750 SPP_0022 Streptococcus pneumoniae P1031 transposase YP_002737261.1 20422 D 488223 CDS YP_002737262.1 225855751 7681697 21178..21312 1 NC_012467.1 identified by glimmer; putative; hypothetical protein 21312 7681697 SPP_0023 Streptococcus pneumoniae P1031 hypothetical protein YP_002737262.1 21178 D 488223 CDS YP_002737263.1 225855752 7681890 22365..22601 1 NC_012467.1 hypothetical protein 22601 7681890 SPP_0026 Streptococcus pneumoniae P1031 hypothetical protein YP_002737263.1 22365 D 488223 CDS YP_002737264.1 225855753 7682486 22790..24118 1 NC_012467.1 catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis; adenylosuccinate synthetase 24118 purA 7682486 purA Streptococcus pneumoniae P1031 adenylosuccinate synthetase YP_002737264.1 22790 D 488223 CDS YP_002737265.1 225855754 7681563 complement(24350..25498) 1 NC_012467.1 identified by match to protein family HMM PF00589; integrase 25498 7681563 SPP_0028 Streptococcus pneumoniae P1031 integrase YP_002737265.1 24350 R 488223 CDS YP_002737266.1 225855755 7681879 complement(25673..26485) 1 NC_012467.1 identified by glimmer; putative; hypothetical protein 26485 7681879 SPP_0029 Streptococcus pneumoniae P1031 hypothetical protein YP_002737266.1 25673 R 488223 CDS YP_002737267.1 225855756 7681590 complement(26523..26669) 1 NC_012467.1 identified by glimmer; putative; hypothetical protein 26669 7681590 SPP_0030 Streptococcus pneumoniae P1031 hypothetical protein YP_002737267.1 26523 R 488223 CDS YP_002737268.1 225855757 7681286 complement(26745..26903) 1 NC_012467.1 identified by glimmer; putative; hypothetical protein 26903 7681286 SPP_0031 Streptococcus pneumoniae P1031 hypothetical protein YP_002737268.1 26745 R 488223 CDS YP_002737269.1 225855758 7681812 complement(26916..27179) 1 NC_012467.1 identified by match to protein family HMM PF05016; match to protein family HMM TIGR02385; plasmid addiction system poison protein 27179 7681812 SPP_0032 Streptococcus pneumoniae P1031 plasmid addiction system poison protein YP_002737269.1 26916 R 488223 CDS YP_002737270.1 225855759 7681314 complement(27179..27412) 1 NC_012467.1 hypothetical protein 27412 7681314 SPP_0033 Streptococcus pneumoniae P1031 hypothetical protein YP_002737270.1 27179 R 488223 CDS YP_002737271.1 225855760 7682696 complement(27412..27780) 1 NC_012467.1 identified by match to protein family HMM PF01381; phage transcriptional regulator, Cro/CI family 27780 7682696 SPP_0034 Streptococcus pneumoniae P1031 phage transcriptional regulator, Cro/CI family YP_002737271.1 27412 R 488223 CDS YP_002737272.1 225855761 7680973 28065..28211 1 NC_012467.1 hypothetical protein 28211 7680973 SPP_0035 Streptococcus pneumoniae P1031 hypothetical protein YP_002737272.1 28065 D 488223 CDS YP_002737273.1 225855762 7682205 28622..28825 1 NC_012467.1 hypothetical protein 28825 7682205 SPP_0036 Streptococcus pneumoniae P1031 hypothetical protein YP_002737273.1 28622 D 488223 CDS YP_002737274.1 225855763 7682785 28842..29039 1 NC_012467.1 hypothetical protein 29039 7682785 SPP_0037 Streptococcus pneumoniae P1031 hypothetical protein YP_002737274.1 28842 D 488223 CDS YP_002737275.1 225855764 7681737 complement(29206..29631) 1 NC_012467.1 phage protein, putative 29631 7681737 SPP_0038 Streptococcus pneumoniae P1031 phage protein, putative YP_002737275.1 29206 R 488223 CDS YP_002737276.1 225855765 7681222 29685..30398 1 NC_012467.1 identified by match to protein family HMM PF02498; gp15 30398 7681222 SPP_0039 Streptococcus pneumoniae P1031 gp15 YP_002737276.1 29685 D 488223 CDS YP_002737277.1 225855766 7681000 30411..30668 1 NC_012467.1 phage protein 30668 7681000 SPP_0040 Streptococcus pneumoniae P1031 phage protein YP_002737277.1 30411 D 488223 CDS YP_002737278.1 225855767 7682313 30754..31074 1 NC_012467.1 hypothetical protein 31074 7682313 SPP_0041 Streptococcus pneumoniae P1031 hypothetical protein YP_002737278.1 30754 D 488223 CDS YP_002737279.1 225855768 7681495 31090..31386 1 NC_012467.1 gp18 31386 7681495 SPP_0042 Streptococcus pneumoniae P1031 gp18 YP_002737279.1 31090 D 488223 CDS YP_002737280.1 225855769 7682575 31370..32206 1 NC_012467.1 identified by match to protein family HMM PF04271; match to protein family HMM TIGR01446; match to protein family HMM TIGR01714; gp19 32206 7682575 SPP_0043 Streptococcus pneumoniae P1031 gp19 YP_002737280.1 31370 D 488223 CDS YP_002737281.1 225855770 7682287 32194..32352 1 NC_012467.1 hypothetical protein 32352 7682287 SPP_0044 Streptococcus pneumoniae P1031 hypothetical protein YP_002737281.1 32194 D 488223 CDS YP_002737282.1 225855771 7682161 32475..33116 1 NC_012467.1 gp21 33116 7682161 SPP_0045 Streptococcus pneumoniae P1031 gp21 YP_002737282.1 32475 D 488223 CDS YP_002737283.1 225855772 7682035 33131..33325 1 NC_012467.1 identified by glimmer; putative; hypothetical protein 33325 7682035 SPP_0046 Streptococcus pneumoniae P1031 hypothetical protein YP_002737283.1 33131 D 488223 CDS YP_002737284.1 225855773 7680670 33325..33552 1 NC_012467.1 hypothetical protein 33552 7680670 SPP_0047 Streptococcus pneumoniae P1031 hypothetical protein YP_002737284.1 33325 D 488223 CDS YP_002737285.1 225855774 7681167 33679..33846 1 NC_012467.1 identified by glimmer; putative; hypothetical protein 33846 7681167 SPP_0048 Streptococcus pneumoniae P1031 hypothetical protein YP_002737285.1 33679 D 488223 CDS YP_002737286.1 225855775 7682504 34014..34343 1 NC_012467.1 gp24 34343 7682504 SPP_0049 Streptococcus pneumoniae P1031 gp24 YP_002737286.1 34014 D 488223 CDS YP_002737287.1 225855776 7682379 34333..34758 1 NC_012467.1 identified by match to protein family HMM PF07852; hypothetical protein 34758 7682379 SPP_0050 Streptococcus pneumoniae P1031 hypothetical protein YP_002737287.1 34333 D 488223 CDS YP_002737288.1 225855777 7681505 35314..35658 1 NC_012467.1 identified by match to protein family HMM TIGR01671; hypothetical protein 35658 7681505 SPP_0053 Streptococcus pneumoniae P1031 hypothetical protein YP_002737288.1 35314 D 488223 CDS YP_002737289.1 225855778 7682603 35658..35894 1 NC_012467.1 gp29 35894 7682603 SPP_0054 Streptococcus pneumoniae P1031 gp29 YP_002737289.1 35658 D 488223 CDS YP_002737290.1 225855779 7681500 35906..36049 1 NC_012467.1 identified by glimmer; putative; hypothetical protein 36049 7681500 SPP_0055 Streptococcus pneumoniae P1031 hypothetical protein YP_002737290.1 35906 D 488223 CDS YP_002737291.1 225855780 7682177 36851..37393 1 NC_012467.1 identified by match to protein family HMM PF00589; prophage LambdaSa2, site-specific recombinase, phage integrase family 37393 7682177 SPP_0056 Streptococcus pneumoniae P1031 prophage LambdaSa2, site-specific recombinase, phage integrase family YP_002737291.1 36851 D 488223 CDS YP_002737292.1 225855781 7681466 37557..37748 1 NC_012467.1 identified by glimmer; putative; hypothetical protein 37748 7681466 SPP_0057 Streptococcus pneumoniae P1031 hypothetical protein YP_002737292.1 37557 D 488223 CDS YP_002737293.1 225855782 7682703 37868..38188 1 NC_012467.1 hypothetical protein 38188 7682703 SPP_0058 Streptococcus pneumoniae P1031 hypothetical protein YP_002737293.1 37868 D 488223 CDS YP_002737294.1 225855783 7681160 38326..38718 1 NC_012467.1 hypothetical protein 38718 7681160 SPP_0059 Streptococcus pneumoniae P1031 hypothetical protein YP_002737294.1 38326 D 488223 CDS YP_002737295.1 225855784 7681668 38711..40441 1 NC_012467.1 identified by match to protein family HMM PF03354; putative phage terminase, large subunit 40441 7681668 SPP_0060 Streptococcus pneumoniae P1031 putative phage terminase, large subunit YP_002737295.1 38711 D 488223 CDS YP_002737296.1 225855785 7682250 40449..40667 1 NC_012467.1 identified by glimmer; putative; hypothetical protein 40667 7682250 SPP_0061 Streptococcus pneumoniae P1031 hypothetical protein YP_002737296.1 40449 D 488223 CDS YP_002737297.1 225855786 7682692 40685..41887 1 NC_012467.1 identified by match to protein family HMM PF04860; match to protein family HMM TIGR01537; phage portal protein, HK97 family 41887 7682692 SPP_0062 Streptococcus pneumoniae P1031 phage portal protein, HK97 family YP_002737297.1 40685 D 488223 CDS YP_002737298.1 225855787 7680811 41871..42446 1 NC_012467.1 identified by match to protein family HMM PF04586; match to protein family HMM TIGR01543; phage prohead protease, HK97 family 42446 7680811 SPP_0063 Streptococcus pneumoniae P1031 phage prohead protease, HK97 family YP_002737298.1 41871 D 488223 CDS YP_002737299.1 225855788 7681194 42443..43615 1 NC_012467.1 identified by match to protein family HMM PF05065; match to protein family HMM TIGR01554; phage major capsid protein, HK97 family 43615 7681194 SPP_0064 Streptococcus pneumoniae P1031 phage major capsid protein, HK97 family YP_002737299.1 42443 D 488223 CDS YP_002737300.1 225855789 7680985 43627..43917 1 NC_012467.1 hypothetical protein 43917 7680985 SPP_0065 Streptococcus pneumoniae P1031 hypothetical protein YP_002737300.1 43627 D 488223 CDS YP_002737301.1 225855790 7682834 43920..44201 1 NC_012467.1 hypothetical protein 44201 7682834 SPP_0066 Streptococcus pneumoniae P1031 hypothetical protein YP_002737301.1 43920 D 488223 CDS YP_002737302.1 225855791 7682182 44188..44487 1 NC_012467.1 identified by match to protein family HMM TIGR01563; phage head-tail adaptor, putative 44487 7682182 SPP_0067 Streptococcus pneumoniae P1031 phage head-tail adaptor, putative YP_002737302.1 44188 D 488223 CDS YP_002737303.1 225855792 7682138 44484..44831 1 NC_012467.1 prophage pi2 protein 37 44831 7682138 SPP_0068 Streptococcus pneumoniae P1031 prophage pi2 protein 37 YP_002737303.1 44484 D 488223 CDS YP_002737304.1 225855793 7682582 44828..45151 1 NC_012467.1 hypothetical protein 45151 7682582 SPP_0069 Streptococcus pneumoniae P1031 hypothetical protein YP_002737304.1 44828 D 488223 CDS YP_002737305.1 225855794 7680933 45163..45741 1 NC_012467.1 identified by match to protein family HMM TIGR01603; prophage pi2 protein 39 45741 7680933 SPP_0070 Streptococcus pneumoniae P1031 prophage pi2 protein 39 YP_002737305.1 45163 D 488223 CDS YP_002737306.1 225855795 7682658 45753..46172 1 NC_012467.1 prophage pi2 protein 40 46172 7682658 SPP_0071 Streptococcus pneumoniae P1031 prophage pi2 protein 40 YP_002737306.1 45753 D 488223 CDS YP_002737307.1 225855796 7681973 46450..49209 1 NC_012467.1 identified by match to protein family HMM PF05017; prophage LambdaSa04, tail tape measure protein, family 49209 7681973 SPP_0072 Streptococcus pneumoniae P1031 prophage LambdaSa04, tail tape measure protein, family YP_002737307.1 46450 D 488223 CDS YP_002737308.1 225855797 7680879 49206..49928 1 NC_012467.1 hypothetical protein 49928 7680879 SPP_0073 Streptococcus pneumoniae P1031 hypothetical protein YP_002737308.1 49206 D 488223 CDS YP_002737309.1 225855798 7682122 49929..53150 1 NC_012467.1 identified by match to protein family HMM TIGR01665; host specificity protein 53150 7682122 SPP_0074 Streptococcus pneumoniae P1031 host specificity protein YP_002737309.1 49929 D 488223 CDS YP_002737310.1 225855799 7682093 53196..55844 1 NC_012467.1 PblB 55844 7682093 SPP_0075 Streptococcus pneumoniae P1031 PblB YP_002737310.1 53196 D 488223 CDS YP_002737311.1 225855800 7681829 55993..56415 1 NC_012467.1 identified by glimmer; putative; hypothetical protein 56415 7681829 SPP_0076 Streptococcus pneumoniae P1031 hypothetical protein YP_002737311.1 55993 D 488223 CDS YP_002737312.1 225855801 7681874 56412..56528 1 NC_012467.1 identified by glimmer; putative; hypothetical protein 56528 7681874 SPP_0077 Streptococcus pneumoniae P1031 hypothetical protein YP_002737312.1 56412 D 488223 CDS YP_002737313.1 225855802 7681531 56509..56712 1 NC_012467.1 hypothetical protein 56712 7681531 SPP_0078 Streptococcus pneumoniae P1031 hypothetical protein YP_002737313.1 56509 D 488223 CDS YP_002737314.1 225855803 7681289 56715..56975 1 NC_012467.1 identified by glimmer; putative; hypothetical protein 56975 7681289 SPP_0079 Streptococcus pneumoniae P1031 hypothetical protein YP_002737314.1 56715 D 488223 CDS YP_002737315.1 225855804 7682772 56927..57067 1 NC_012467.1 identified by glimmer; putative; hypothetical protein 57067 7682772 SPP_0080 Streptococcus pneumoniae P1031 hypothetical protein YP_002737315.1 56927 D 488223 CDS YP_002737316.1 225855805 7682528 57077..57493 1 NC_012467.1 identified by match to protein family HMM PF05105; match to protein family HMM TIGR01593; putative holin 1 57493 7682528 SPP_0081 Streptococcus pneumoniae P1031 putative holin 1 YP_002737316.1 57077 D 488223 CDS YP_002737317.1 225855806 7682260 57497..57832 1 NC_012467.1 identified by match to protein family HMM TIGR01673; phage holin, LL-H family 57832 7682260 SPP_0082 Streptococcus pneumoniae P1031 phage holin, LL-H family YP_002737317.1 57497 D 488223 CDS YP_002737318.1 225855807 7680687 57832..58788 1 NC_012467.1 identified by match to protein family HMM PF01473; match to protein family HMM PF01510; lytic amidase (N-acetylmuramoyl-L-alanine amidase) 58788 7680687 SPP_0083 Streptococcus pneumoniae P1031 lytic amidase (N-acetylmuramoyl-L-alanine amidase) YP_002737318.1 57832 D 488223 CDS YP_002737319.1 225855808 7682434 complement(59058..59237) 1 NC_012467.1 hypothetical protein 59237 7682434 SPP_0084 Streptococcus pneumoniae P1031 hypothetical protein YP_002737319.1 59058 R 488223 CDS YP_002737320.1 225855809 7681059 59810..60277 1 NC_012467.1 identified by match to protein family HMM PF00383; tRNA-specific adenosine deaminase 60277 7681059 SPP_0085 Streptococcus pneumoniae P1031 tRNA-specific adenosine deaminase YP_002737320.1 59810 D 488223 CDS YP_002737321.1 225855810 7682146 60464..60907 1 NC_012467.1 catalyzes the formation of dUMP from dUTP; deoxyuridine 5'-triphosphate nucleotidohydrolase 60907 dut 7682146 dut Streptococcus pneumoniae P1031 deoxyuridine 5'-triphosphate nucleotidohydrolase YP_002737321.1 60464 D 488223 CDS YP_002737322.1 225855811 7680958 60867..61424 1 NC_012467.1 identified by match to protein family HMM PF00300; phosphoglycerate mutase family protein 61424 7680958 SPP_0087 Streptococcus pneumoniae P1031 phosphoglycerate mutase family protein YP_002737322.1 60867 D 488223 CDS YP_002737323.1 225855812 7681475 61537..62799 1 NC_012467.1 Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents; DNA repair protein RadA 62799 radA 7681475 radA Streptococcus pneumoniae P1031 DNA repair protein RadA YP_002737323.1 61537 D 488223 CDS YP_002737324.1 225855813 7680792 62872..63369 1 NC_012467.1 identified by match to protein family HMM PF00484; carbonate dehydratase 63369 7680792 SPP_0089 Streptococcus pneumoniae P1031 carbonate dehydratase YP_002737324.1 62872 D 488223 CDS YP_002737325.1 225855814 7682360 63394..63588 1 NC_012467.1 identified by glimmer; putative; hypothetical protein 63588 7682360 SPP_0090 Streptococcus pneumoniae P1031 hypothetical protein YP_002737325.1 63394 D 488223 CDS YP_002737326.1 225855815 7682348 63570..64193 1 NC_012467.1 hypothetical protein 64193 7682348 SPP_0091 Streptococcus pneumoniae P1031 hypothetical protein YP_002737326.1 63570 D 488223 CDS YP_002737327.1 225855816 7682422 64338..65306 1 NC_012467.1 catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP; ribose-phosphate pyrophosphokinase 65306 7682422 SPP_0092 Streptococcus pneumoniae P1031 ribose-phosphate pyrophosphokinase YP_002737327.1 64338 D 488223 CDS YP_002737328.1 225855817 7681074 complement(65848..66081) 1 NC_012467.1 hypothetical protein 66081 7681074 SPP_0093 Streptococcus pneumoniae P1031 hypothetical protein YP_002737328.1 65848 R 488223 CDS YP_002737329.1 225855818 7681628 complement(66405..66719) 1 NC_012467.1 hypothetical protein 66719 7681628 SPP_0094 Streptococcus pneumoniae P1031 hypothetical protein YP_002737329.1 66405 R 488223 CDS YP_002737330.1 225855819 7682101 67011..69644 1 NC_012467.1 has 3'-5' exonuclease, 5'-3' exonuclease and 5'-3'polymerase activities, primarily functions to fill gaps during DNA replication and repair; DNA polymerase I 69644 7682101 SPP_0095 Streptococcus pneumoniae P1031 DNA polymerase I YP_002737330.1 67011 D 488223 CDS YP_002737331.1 225855820 7681706 69729..70166 1 NC_012467.1 identified by match to protein family HMM PF02629; CoA binding protein 70166 7681706 SPP_0096 Streptococcus pneumoniae P1031 CoA binding protein YP_002737331.1 69729 D 488223 CDS YP_002737332.1 225855821 7681596 70207..70500 1 NC_012467.1 identified by glimmer; putative; hypothetical protein 70500 7681596 SPP_0097 Streptococcus pneumoniae P1031 hypothetical protein YP_002737332.1 70207 D 488223 CDS YP_002737333.1 225855822 7680911 complement(70529..71539) 1 NC_012467.1 identified by match to protein family HMM PF03601; membrane protein Spr0034 71539 7680911 SPP_0098 Streptococcus pneumoniae P1031 membrane protein Spr0034 YP_002737333.1 70529 R 488223 CDS YP_002737334.1 225855823 7680788 71688..72857 1 NC_012467.1 catalyzes the transamination of the aromatic amino acid forming a ketoacid; first step in aromatic amino acid degradation in lactococci; aromatic amino acid aminotransferase 72857 7680788 SPP_0099 Streptococcus pneumoniae P1031 aromatic amino acid aminotransferase YP_002737334.1 71688 D 488223 CDS YP_002737335.1 225855824 7681461 72854..73624 1 NC_012467.1 involved in DNA repair and RecFOR pathway recombination; RecFOR proteins displace ssDNA-binding protein and facilitate the production of RecA-coated ssDNA; DNA repair protein RecO 73624 recO 7681461 recO Streptococcus pneumoniae P1031 DNA repair protein RecO YP_002737335.1 72854 D 488223 CDS YP_002737336.1 225855825 7682009 73621..74613 1 NC_012467.1 involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsY; putative glycerol-3-phosphate acyltransferase PlsX 74613 plsX 7682009 plsX Streptococcus pneumoniae P1031 putative glycerol-3-phosphate acyltransferase PlsX YP_002737336.1 73621 D 488223 CDS YP_002737337.1 225855826 7682712 74619..74852 1 NC_012467.1 hypothetical protein 74852 7682712 SPP_0102 Streptococcus pneumoniae P1031 hypothetical protein YP_002737337.1 74619 D 488223 CDS YP_002737338.1 225855827 7682135 74895..75188 1 NC_012467.1 mobile genetic element 75188 7682135 SPP_0103 Streptococcus pneumoniae P1031 mobile genetic element YP_002737338.1 74895 D 488223 CDS YP_002737339.1 225855828 7682596 75391..75621 1 NC_012467.1 identified by match to protein family HMM TIGR01847; hypothetical protein 75621 7682596 SPP_0104 Streptococcus pneumoniae P1031 hypothetical protein YP_002737339.1 75391 D 488223 CDS YP_002737340.1 225855829 7682496 75624..75749 1 NC_012467.1 hypothetical protein 75749 7682496 SPP_0105 Streptococcus pneumoniae P1031 hypothetical protein YP_002737340.1 75624 D 488223 CDS YP_002737341.1 225855830 7681513 complement(76196..76309) 1 NC_012467.1 identified by glimmer; putative; hypothetical protein 76309 7681513 SPP_0106 Streptococcus pneumoniae P1031 hypothetical protein YP_002737341.1 76196 R 488223 CDS YP_002737342.1 225855831 7680704 76336..78489 1 NC_012467.1 identified by match to protein family HMM PF00005; match to protein family HMM PF00664; match to protein family HMM PF03412; match to protein family HMM TIGR01193; transport/processing ATP-binding protein ComA 78489 7680704 SPP_0107 Streptococcus pneumoniae P1031 transport/processing ATP-binding protein ComA YP_002737342.1 76336 D 488223 CDS YP_002737343.1 225855832 7681067 78502..79851 1 NC_012467.1 identified by match to protein family HMM TIGR01000; transport protein ComB 79851 7681067 SPP_0108 Streptococcus pneumoniae P1031 transport protein ComB YP_002737343.1 78502 D 488223 CDS YP_002737344.1 225855833 7682530 80021..80728 1 NC_012467.1 catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis; SAICAR synthase; phosphoribosylaminoimidazole-succinocarboxamide synthase 80728 purC 7682530 purC Streptococcus pneumoniae P1031 phosphoribosylaminoimidazole-succinocarboxamide synthase YP_002737344.1 80021 D 488223 CDS YP_002737345.1 225855834 7682280 80930..84655 1 NC_012467.1 identified by match to protein family HMM PF02769; match to protein family HMM TIGR01857; phosphoribosylformylglycinamidine synthase 84655 7682280 SPP_0110 Streptococcus pneumoniae P1031 phosphoribosylformylglycinamidine synthase YP_002737345.1 80930 D 488223 CDS YP_002737346.1 225855835 7681955 84748..86190 1 NC_012467.1 Catalyzes first step of the de novo purine nucleotide biosynthetic pathway; amidophosphoribosyltransferase 86190 purF 7681955 purF Streptococcus pneumoniae P1031 amidophosphoribosyltransferase YP_002737346.1 84748 D 488223 CDS YP_002737347.1 225855836 7681212 86227..87249 1 NC_012467.1 catalyzes the formation of 1-(5-phosphoribosyl)-5-aminoimidazole from 2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in purine biosynthesis; phosphoribosylaminoimidazole synthetase 87249 purM 7681212 purM Streptococcus pneumoniae P1031 phosphoribosylaminoimidazole synthetase YP_002737347.1 86227 D 488223 CDS YP_002737348.1 225855837 7681729 87246..87791 1 NC_012467.1 glycinamide ribonucleotide transformylase; GAR Tfase; catalyzes the synthesis of 5'-phosphoribosylformylglycinamide from 5'-phosphoribosylglycinamide and 10-formyltetrahydrofolate; PurN requires formyl folate for the reaction unlike PurT which uses formate; phosphoribosylglycinamide formyltransferase 87791 purN 7681729 purN Streptococcus pneumoniae P1031 phosphoribosylglycinamide formyltransferase YP_002737348.1 87246 D 488223 CDS YP_002737349.1 225855838 7681372 87875..88384 1 NC_012467.1 identified by match to protein family HMM PF04892; teicoplanin resistance protein 88384 7681372 SPP_0114 Streptococcus pneumoniae P1031 teicoplanin resistance protein YP_002737349.1 87875 D 488223 CDS YP_002737350.1 225855839 7681646 88409..89956 1 NC_012467.1 involved in de novo purine biosynthesis; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 89956 purH 7681646 purH Streptococcus pneumoniae P1031 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase YP_002737350.1 88409 D 488223 CDS YP_002737351.1 225855840 7682651 90078..91340 1 NC_012467.1 catalyzes the formation of N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-D-ribosylamine and glycine in purine biosynthesis; phosphoribosylamine--glycine ligase 91340 purD 7682651 purD Streptococcus pneumoniae P1031 phosphoribosylamine--glycine ligase YP_002737351.1 90078 D 488223 CDS YP_002737352.1 225855841 7682803 91597..91713 1 NC_012467.1 hypothetical protein 91713 7682803 SPP_0117 Streptococcus pneumoniae P1031 hypothetical protein YP_002737352.1 91597 D 488223 CDS YP_002737353.1 225855842 7681820 91743..92231 1 NC_012467.1 identified by match to protein family HMM PF00731; match to protein family HMM TIGR01162; phosphoribosylaminoimidazole carboxylase, catalytic subunit 92231 purE 7681820 purE Streptococcus pneumoniae P1031 phosphoribosylaminoimidazole carboxylase, catalytic subunit YP_002737353.1 91743 D 488223 CDS YP_002737354.1 225855843 7681343 92218..93309 1 NC_012467.1 With PurE catalyzes the conversion of aminoimidazole ribonucleotide to carboxyaminoimidazole ribonucleotide in the de novo purine nucleotide biosynthetic pathway; phosphoribosylaminoimidazole carboxylase ATPase subunit 93309 purK 7681343 purK Streptococcus pneumoniae P1031 phosphoribosylaminoimidazole carboxylase ATPase subunit YP_002737354.1 92218 D 488223 CDS YP_002737355.1 225855844 7682383 93319..93546 1 NC_012467.1 hypothetical protein 93546 7682383 SPP_0120 Streptococcus pneumoniae P1031 hypothetical protein YP_002737355.1 93319 D 488223 CDS YP_002737356.1 225855845 7681861 93609..94907 1 NC_012467.1 Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide; adenylosuccinate lyase 94907 purB 7681861 purB Streptococcus pneumoniae P1031 adenylosuccinate lyase YP_002737356.1 93609 D 488223 CDS YP_002737357.1 225855846 7681331 complement(94962..98897) 1 NC_012467.1 identified by match to protein family HMM PF00728; match to protein family HMM PF00746; match to protein family HMM PF04650; match to protein family HMM PF07501; match to protein family HMM TIGR01167; match to protein family HMM TIGR01168; beta-N-acetylhexosaminidase 98897 7681331 SPP_0122 Streptococcus pneumoniae P1031 beta-N-acetylhexosaminidase YP_002737357.1 94962 R 488223 CDS YP_002737358.1 225855847 7681398 complement(99213..99956) 1 NC_012467.1 identified by match to protein family HMM PF00392; match to protein family HMM PF07702; GntR family transcriptional regulator 99956 7681398 SPP_0123 Streptococcus pneumoniae P1031 GntR family transcriptional regulator YP_002737358.1 99213 R 488223 CDS YP_002737359.1 225855848 7680686 100277..102064 1 NC_012467.1 identified by match to protein family HMM PF01301; match to protein family HMM PF02449; beta-galactosidase (Lactase) 102064 7680686 SPP_0124 Streptococcus pneumoniae P1031 beta-galactosidase (Lactase) YP_002737359.1 100277 D 488223 CDS YP_002737360.1 225855849 7682459 102061..102537 1 NC_012467.1 identified by match to protein family HMM PF03830; phosphotransferase system sugar-specific eiib component 102537 7682459 SPP_0125 Streptococcus pneumoniae P1031 phosphotransferase system sugar-specific eiib component YP_002737360.1 102061 D 488223 CDS YP_002737361.1 225855850 7682562 102565..103470 1 NC_012467.1 identified by match to protein family HMM PF03609; PTS system, IIC component 103470 7682562 SPP_0126 Streptococcus pneumoniae P1031 PTS system, IIC component YP_002737361.1 102565 D 488223 CDS YP_002737362.1 225855851 7681528 103457..104272 1 NC_012467.1 identified by match to protein family HMM PF03613; PTS system, IID component 104272 7681528 SPP_0127 Streptococcus pneumoniae P1031 PTS system, IID component YP_002737362.1 103457 D 488223 CDS YP_002737363.1 225855852 7682440 104279..104683 1 NC_012467.1 identified by match to protein family HMM PF03610; phosphotransferase system sugar-specific EII component 104683 7682440 SPP_0128 Streptococcus pneumoniae P1031 phosphotransferase system sugar-specific EII component YP_002737363.1 104279 D 488223 CDS YP_002737364.1 225855853 7682593 104982..106148 1 NC_012467.1 identified by match to protein family HMM PF01380; putative tagatose-6-phosphate ketose/aldose isomerase 106148 7682593 SPP_0129 Streptococcus pneumoniae P1031 putative tagatose-6-phosphate ketose/aldose isomerase YP_002737364.1 104982 D 488223 CDS YP_002737365.1 225855854 7681722 106264..107301 1 NC_012467.1 identified by match to protein family HMM PF01263; aldose 1-epimerase 107301 7681722 SPP_0130 Streptococcus pneumoniae P1031 aldose 1-epimerase YP_002737365.1 106264 D 488223 CDS YP_002737366.1 225855855 7681210 107508..108362 1 NC_012467.1 identified by match to protein family HMM PF00903; glyoxalase family protein 108362 7681210 SPP_0131 Streptococcus pneumoniae P1031 glyoxalase family protein YP_002737366.1 107508 D 488223 CDS YP_002737367.1 225855856 7681851 108594..108752 1 NC_012467.1 identified by glimmer; putative; hypothetical protein 108752 7681851 SPP_0132 Streptococcus pneumoniae P1031 hypothetical protein YP_002737367.1 108594 D 488223 CDS YP_002737368.1 225855857 7682752 complement(108794..109201) 1 NC_012467.1 chlorohydrolase 109201 7682752 SPP_0133 Streptococcus pneumoniae P1031 chlorohydrolase YP_002737368.1 108794 R 488223 CDS YP_002737369.1 225855858 7682337 complement(109255..109551) 1 NC_012467.1 identified by match to protein family HMM PF00581; rhodanese family protein 109551 7682337 SPP_0134 Streptococcus pneumoniae P1031 rhodanese family protein YP_002737369.1 109255 R 488223 CDS YP_002737370.1 225855859 7682310 complement(109541..109660) 1 NC_012467.1 coenzyme A disulfide reductase 109660 7682310 SPP_0135 Streptococcus pneumoniae P1031 coenzyme A disulfide reductase YP_002737370.1 109541 R 488223 CDS YP_002737371.1 225855860 7681720 109773..110537 1 NC_012467.1 identified by match to protein family HMM PF01048; phosphorylase, Pnp/Udp family 110537 7681720 SPP_0136 Streptococcus pneumoniae P1031 phosphorylase, Pnp/Udp family YP_002737371.1 109773 D 488223 CDS YP_002737372.1 225855861 7682013 110793..110933 1 NC_012467.1 identified by glimmer; putative; hypothetical protein 110933 7682013 SPP_0137 Streptococcus pneumoniae P1031 hypothetical protein YP_002737372.1 110793 D 488223 CDS YP_002737373.1 225855862 7680964 111102..112481 1 NC_012467.1 identified by match to protein family HMM PF02386; Trk transporter membrane-spanning protein - K+ transport 112481 7680964 SPP_0138 Streptococcus pneumoniae P1031 Trk transporter membrane-spanning protein - K+ transport YP_002737373.1 111102 D 488223 CDS YP_002737374.1 225855863 7680937 112495..113160 1 NC_012467.1 identified by match to protein family HMM PF02254; potassium uptake protein, Trk family 113160 7680937 SPP_0139 Streptococcus pneumoniae P1031 potassium uptake protein, Trk family YP_002737374.1 112495 D 488223 CDS YP_002737375.1 225855864 7681095 113295..113498 1 NC_012467.1 identified by glimmer; putative; hypothetical protein 113498 7681095 SPP_0140 Streptococcus pneumoniae P1031 hypothetical protein YP_002737375.1 113295 D 488223 CDS YP_002737376.1 225855865 7682848 114691..117720 1 NC_012467.1 identified by match to protein family HMM PF00746; match to protein family HMM PF04650; match to protein family HMM TIGR01167; match to protein family HMM TIGR01168; cell wall surface anchor family protein 117720 7682848 SPP_0144 Streptococcus pneumoniae P1031 cell wall surface anchor family protein YP_002737376.1 114691 D 488223 CDS YP_002737377.1 225855866 7681339 117887..118585 1 NC_012467.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00486; response regulator SaeR 118585 7681339 SPP_0145 Streptococcus pneumoniae P1031 response regulator SaeR YP_002737377.1 117887 D 488223 CDS YP_002737378.1 225855867 7681610 118582..119634 1 NC_012467.1 identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518; histidine kinase 119634 7681610 SPP_0146 Streptococcus pneumoniae P1031 histidine kinase YP_002737378.1 118582 D 488223 CDS YP_002737379.1 225855868 7681048 119829..120440 1 NC_012467.1 primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination; 30S ribosomal protein S4 120440 rpsD 7681048 rpsD Streptococcus pneumoniae P1031 30S ribosomal protein S4 YP_002737379.1 119829 D 488223 CDS YP_002737380.1 225855869 7682424 120625..120783 1 NC_012467.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; transposase 120783 7682424 SPP_0148 Streptococcus pneumoniae P1031 transposase YP_002737380.1 120625 D 488223 CDS YP_002737381.1 225855870 7682351 121252..121467 1 NC_012467.1 hypothetical protein 121467 7682351 SPP_0149 Streptococcus pneumoniae P1031 hypothetical protein YP_002737381.1 121252 D 488223 CDS YP_002737382.1 225855871 7681741 121421..121594 1 NC_012467.1 identified by glimmer; putative; hypothetical protein 121594 7681741 SPP_0150 Streptococcus pneumoniae P1031 hypothetical protein YP_002737382.1 121421 D 488223 CDS YP_002737383.1 225855872 7681562 121930..122889 1 NC_012467.1 identified by match to protein family HMM PF00528; sugar ABC transporter permease 122889 7681562 SPP_0151 Streptococcus pneumoniae P1031 sugar ABC transporter permease YP_002737383.1 121930 D 488223 CDS YP_002737384.1 225855873 7680682 122903..123826 1 NC_012467.1 identified by match to protein family HMM PF00528; protein LplC 123826 7680682 SPP_0152 Streptococcus pneumoniae P1031 protein LplC YP_002737384.1 122903 D 488223 CDS YP_002737385.1 225855874 7681946 123910..125385 1 NC_012467.1 identified by match to protein family HMM PF01547; ABC transporter substrate-binding protein 125385 7681946 SPP_0153 Streptococcus pneumoniae P1031 ABC transporter substrate-binding protein YP_002737385.1 123910 D 488223 CDS YP_002737386.1 225855875 7682515 125657..126643 1 NC_012467.1 identified by match to protein family HMM PF00581; hypothetical protein 126643 7682515 SPP_0154 Streptococcus pneumoniae P1031 hypothetical protein YP_002737386.1 125657 D 488223 CDS YP_002737387.1 225855876 7681252 126765..127625 1 NC_012467.1 hypothetical protein 127625 7681252 SPP_0155 Streptococcus pneumoniae P1031 hypothetical protein YP_002737387.1 126765 D 488223 CDS YP_002737388.1 225855877 7681533 complement(127802..128866) 1 NC_012467.1 hypothetical protein 128866 7681533 SPP_0156 Streptococcus pneumoniae P1031 hypothetical protein YP_002737388.1 127802 R 488223 CDS YP_002737389.1 225855878 7682866 complement(128929..129840) 1 NC_012467.1 hypothetical protein 129840 7682866 SPP_0157 Streptococcus pneumoniae P1031 hypothetical protein YP_002737389.1 128929 R 488223 CDS YP_002737390.1 225855879 7680839 complement(129833..130426) 1 NC_012467.1 hypothetical protein 130426 7680839 SPP_0158 Streptococcus pneumoniae P1031 hypothetical protein YP_002737390.1 129833 R 488223 CDS YP_002737391.1 225855880 7682407 complement(130413..130739) 1 NC_012467.1 identified by match to protein family HMM PF03551; transcription regulator 130739 7682407 SPP_0159 Streptococcus pneumoniae P1031 transcription regulator YP_002737391.1 130413 R 488223 CDS YP_002737392.1 225855881 7682517 complement(130878..132044) 1 NC_012467.1 identified by match to protein family HMM PF07690; cyanate permease 132044 7682517 SPP_0160 Streptococcus pneumoniae P1031 cyanate permease YP_002737392.1 130878 R 488223 CDS YP_002737393.1 225855882 7682875 132195..133241 1 NC_012467.1 identified by match to protein family HMM PF00535; glycosyl transferase 133241 7682875 SPP_0161 Streptococcus pneumoniae P1031 glycosyl transferase YP_002737393.1 132195 D 488223 CDS YP_002737394.1 225855883 7682734 133309..135159 1 NC_012467.1 identified by match to protein family HMM PF00106; match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF02719; match to protein family HMM PF04321; match to protein family HMM PF07993; CapD protein, required for the biosynthesis of type 1 capsular polysaccharide 135159 7682734 SPP_0162 Streptococcus pneumoniae P1031 CapD protein, required for the biosynthesis of type 1 capsular polysaccharide YP_002737394.1 133309 D 488223 CDS YP_002737395.1 225855884 7682314 complement(135462..136094) 1 NC_012467.1 identified by match to protein family HMM PF00702; match to protein family HMM TIGR01549; phosphoglycolate phosphatase 136094 7682314 SPP_0164 Streptococcus pneumoniae P1031 phosphoglycolate phosphatase YP_002737395.1 135462 R 488223 CDS YP_002737396.1 225855885 7681003 complement(136116..136988) 1 NC_012467.1 identified by match to protein family HMM PF03313; match to protein family HMM TIGR00718; L-serine dehydratase, iron-sulfur-dependent, alpha subunit 136988 sdaAA 7681003 sdaAA Streptococcus pneumoniae P1031 L-serine dehydratase, iron-sulfur-dependent, alpha subunit YP_002737396.1 136116 R 488223 CDS YP_002737397.1 225855886 7682641 complement(136997..137668) 1 NC_012467.1 identified by match to protein family HMM PF01842; match to protein family HMM PF03315; match to protein family HMM TIGR00719; L-serine dehydratase, iron-sulfur-dependent, beta subunit 137668 sdaAB 7682641 sdaAB Streptococcus pneumoniae P1031 L-serine dehydratase, iron-sulfur-dependent, beta subunit YP_002737397.1 136997 R 488223 CDS YP_002737398.1 225855887 7680675 137910..138482 1 NC_012467.1 identified by match to protein family HMM PF01476; LysM domain protein 138482 7680675 SPP_0167 Streptococcus pneumoniae P1031 LysM domain protein YP_002737398.1 137910 D 488223 CDS YP_002737399.1 225855888 7681159 139279..139563 1 NC_012467.1 identified by match to protein family HMM TIGR01653; bacteriocin, lactococcin 972 family 139563 7681159 SPP_0168 Streptococcus pneumoniae P1031 bacteriocin, lactococcin 972 family YP_002737399.1 139279 D 488223 CDS YP_002737400.1 225855889 7682535 139618..141726 1 NC_012467.1 identified by match to protein family HMM TIGR01654; amino acid ABC transporter permease 141726 7682535 SPP_0169 Streptococcus pneumoniae P1031 amino acid ABC transporter permease YP_002737400.1 139618 D 488223 CDS YP_002737401.1 225855890 7682722 141723..142364 1 NC_012467.1 identified by match to protein family HMM PF00005; macrolide export ATP-binding/permease protein MacB 142364 7682722 SPP_0170 Streptococcus pneumoniae P1031 macrolide export ATP-binding/permease protein MacB YP_002737401.1 141723 D 488223 CDS YP_002737402.1 225855891 7682020 142571..143377 1 NC_012467.1 identified by match to protein family HMM PF00497; amino acid ABC transporter substrate-binding protein 143377 7682020 SPP_0171 Streptococcus pneumoniae P1031 amino acid ABC transporter substrate-binding protein YP_002737402.1 142571 D 488223 CDS YP_002737403.1 225855892 7680814 143394..143813 1 NC_012467.1 identified by match to protein family HMM PF00764; argininosuccinate synthase 143813 argG 7680814 argG Streptococcus pneumoniae P1031 argininosuccinate synthase YP_002737403.1 143394 D 488223 CDS YP_002737404.1 225855893 7682254 complement(144103..144423) 1 NC_012467.1 hypothetical protein 144423 7682254 SPP_0173 Streptococcus pneumoniae P1031 hypothetical protein YP_002737404.1 144103 R 488223 CDS YP_002737405.1 225855894 7680693 145187..145567 1 NC_012467.1 hypothetical protein 145567 7680693 SPP_0174 Streptococcus pneumoniae P1031 hypothetical protein YP_002737405.1 145187 D 488223 CDS YP_002737406.1 225855895 7681105 145941..146999 1 NC_012467.1 hypothetical protein 146999 7681105 SPP_0175 Streptococcus pneumoniae P1031 hypothetical protein YP_002737406.1 145941 D 488223 CDS YP_002737407.1 225855896 7682485 147314..148129 1 NC_012467.1 identified by glimmer; putative; hypothetical protein 148129 7682485 SPP_0176 Streptococcus pneumoniae P1031 hypothetical protein YP_002737407.1 147314 D 488223 CDS YP_002737408.1 225855897 7680859 148123..148290 1 NC_012467.1 identified by glimmer; putative; hypothetical protein 148290 7680859 SPP_0177 Streptococcus pneumoniae P1031 hypothetical protein YP_002737408.1 148123 D 488223 CDS YP_002737409.1 225855898 7682349 148667..149041 1 NC_012467.1 hypothetical protein 149041 7682349 SPP_0178 Streptococcus pneumoniae P1031 hypothetical protein YP_002737409.1 148667 D 488223 CDS YP_002737410.1 225855899 7681446 149048..149230 1 NC_012467.1 hypothetical protein 149230 7681446 SPP_0179 Streptococcus pneumoniae P1031 hypothetical protein YP_002737410.1 149048 D 488223 CDS YP_002737411.1 225855900 7681509 149249..150151 1 NC_012467.1 hypothetical protein 150151 7681509 SPP_0180 Streptococcus pneumoniae P1031 hypothetical protein YP_002737411.1 149249 D 488223 CDS YP_002737412.1 225855901 7681178 150207..150560 1 NC_012467.1 hypothetical protein 150560 7681178 SPP_0181 Streptococcus pneumoniae P1031 hypothetical protein YP_002737412.1 150207 D 488223 CDS YP_002737413.1 225855902 7682508 150527..151285 1 NC_012467.1 hypothetical protein 151285 7682508 SPP_0182 Streptococcus pneumoniae P1031 hypothetical protein YP_002737413.1 150527 D 488223 CDS YP_002737414.1 225855903 7682246 152513..152656 1 NC_012467.1 hypothetical protein 152656 7682246 SPP_0183 Streptococcus pneumoniae P1031 hypothetical protein YP_002737414.1 152513 D 488223 CDS YP_002737415.1 225855904 7682572 152753..152920 1 NC_012467.1 identified by glimmer; putative; hypothetical protein 152920 7682572 SPP_0184 Streptococcus pneumoniae P1031 hypothetical protein YP_002737415.1 152753 D 488223 CDS YP_002737416.1 225855905 7680830 153206..155041 1 NC_012467.1 identified by match to protein family HMM PF01473; surface protein PspA 155041 7680830 SPP_0185 Streptococcus pneumoniae P1031 surface protein PspA YP_002737416.1 153206 D 488223 CDS YP_002737417.1 225855906 7681779 155442..156563 1 NC_012467.1 catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs; tRNA-specific 2-thiouridylase MnmA 156563 mnmA 7681779 mnmA Streptococcus pneumoniae P1031 tRNA-specific 2-thiouridylase MnmA YP_002737417.1 155442 D 488223 CDS YP_002737418.1 225855907 7680786 156704..157159 1 NC_012467.1 identified by match to protein family HMM PF00293; MutT/nudix family protein 157159 7680786 SPP_0187 Streptococcus pneumoniae P1031 MutT/nudix family protein YP_002737418.1 156704 D 488223 CDS YP_002737419.1 225855908 7682510 157169..159082 1 NC_012467.1 GidA; glucose-inhibited cell division protein A; involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U) of the wobble uridine base in some tRNAs; tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA 159082 gidA 7682510 gidA Streptococcus pneumoniae P1031 tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA YP_002737419.1 157169 D 488223 CDS YP_002737420.1 225855909 7682710 159286..159444 1 NC_012467.1 identified by glimmer; putative; hypothetical protein 159444 7682710 SPP_0189 Streptococcus pneumoniae P1031 hypothetical protein YP_002737420.1 159286 D 488223 CDS YP_002737421.1 225855910 7682366 complement(159461..161140) 1 NC_012467.1 identified by match to protein family HMM PF00753; match to protein family HMM PF07521; match to protein family HMM TIGR00649; metallo-beta-lactamase superfamily protein domain protein 161140 7682366 SPP_0190 Streptococcus pneumoniae P1031 metallo-beta-lactamase superfamily protein domain protein YP_002737421.1 159461 R 488223 CDS YP_002737422.1 225855911 7682478 complement(161142..161375) 1 NC_012467.1 identified by match to protein family HMM PF07288; hypothetical protein 161375 7682478 SPP_0191 Streptococcus pneumoniae P1031 hypothetical protein YP_002737422.1 161142 R 488223 CDS YP_002737423.1 225855912 7681040 161759..161968 1 NC_012467.1 identified by glimmer; putative; hypothetical protein 161968 7681040 SPP_0192 Streptococcus pneumoniae P1031 hypothetical protein YP_002737423.1 161759 D 488223 CDS YP_002737424.1 225855913 7680925 complement(162181..162333) 1 NC_012467.1 identified by match to protein family HMM TIGR01847; bacteriocin-type signal sequence domain protein 162333 7680925 SPP_0193 Streptococcus pneumoniae P1031 bacteriocin-type signal sequence domain protein YP_002737424.1 162181 R 488223 CDS YP_002737425.1 225855914 7681602 complement(162335..162520) 1 NC_012467.1 hypothetical protein 162520 7681602 SPP_0194 Streptococcus pneumoniae P1031 hypothetical protein YP_002737425.1 162335 R 488223 CDS YP_002737426.1 225855915 7681843 162698..163381 1 NC_012467.1 identified by match to protein family HMM PF00814; glycoprotein endopeptidase 163381 7681843 SPP_0195 Streptococcus pneumoniae P1031 glycoprotein endopeptidase YP_002737426.1 162698 D 488223 CDS YP_002737427.1 225855916 7682145 163378..163815 1 NC_012467.1 identified by match to protein family HMM PF00583; match to protein family HMM TIGR01575; ribosomal-protein-alanine acetyltransferase 163815 rimI 7682145 rimI Streptococcus pneumoniae P1031 ribosomal-protein-alanine acetyltransferase YP_002737427.1 163378 D 488223 CDS YP_002737428.1 225855917 7680838 163805..164815 1 NC_012467.1 in most organisms, only the N-terminal domain is present in a single polypeptide; in some archaea this domain is fused to a kinase domain; this gene is essential for growth in Escherichia coli and Bacillus subtilis; the secreted glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins; the Pyrococcus structure shows DNA-binding properties, iron-binding, ATP-binding, and AP endonuclease activity; putative DNA-binding/iron metalloprotein/AP endonuclease 164815 7680838 SPP_0197 Streptococcus pneumoniae P1031 putative DNA-binding/iron metalloprotein/AP endonuclease YP_002737428.1 163805 D 488223 CDS YP_002737429.1 225855918 7682735 complement(166869..167072) 1 NC_012467.1 degenerative transposase 167072 7682735 SPP_0200 Streptococcus pneumoniae P1031 degenerative transposase YP_002737429.1 166869 R 488223 CDS YP_002737430.1 225855919 7682132 169592..171208 1 NC_012467.1 identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 171208 7682132 SPP_0205 Streptococcus pneumoniae P1031 ABC transporter ATP-binding protein YP_002737430.1 169592 D 488223 CDS YP_002737431.1 225855920 7682416 172139..172426 1 NC_012467.1 hypothetical protein 172426 7682416 SPP_0206 Streptococcus pneumoniae P1031 hypothetical protein YP_002737431.1 172139 D 488223 CDS YP_002737432.1 225855921 7682046 172404..172949 1 NC_012467.1 identified by glimmer; putative; hypothetical protein 172949 7682046 SPP_0207 Streptococcus pneumoniae P1031 hypothetical protein YP_002737432.1 172404 D 488223 CDS YP_002737433.1 225855922 7681188 172987..173640 1 NC_012467.1 hypothetical protein 173640 7681188 SPP_0208 Streptococcus pneumoniae P1031 hypothetical protein YP_002737433.1 172987 D 488223 CDS YP_002737434.1 225855923 7682532 173652..174401 1 NC_012467.1 identified by match to protein family HMM PF02585; GlcNAc-PI de-N-acetylase family 174401 7682532 SPP_0209 Streptococcus pneumoniae P1031 GlcNAc-PI de-N-acetylase family YP_002737434.1 173652 D 488223 CDS YP_002737435.1 225855924 7682827 174414..175586 1 NC_012467.1 identified by match to protein family HMM PF00984; match to protein family HMM PF03721; match to protein family HMM TIGR03026; UDP-glucose 6-dehydrogenase 175586 7682827 SPP_0210 Streptococcus pneumoniae P1031 UDP-glucose 6-dehydrogenase YP_002737435.1 174414 D 488223 CDS YP_002737436.1 225855925 7680664 175981..176844 1 NC_012467.1 identified by match to protein family HMM TIGR01716; MutR 176844 7680664 SPP_0211 Streptococcus pneumoniae P1031 MutR YP_002737436.1 175981 D 488223 CDS YP_002737437.1 225855926 7681795 177130..177363 1 NC_012467.1 hypothetical protein 177363 7681795 SPP_0212 Streptococcus pneumoniae P1031 hypothetical protein YP_002737437.1 177130 D 488223 CDS YP_002737438.1 225855927 7681927 177385..178062 1 NC_012467.1 identified by match to protein family HMM PF02517; caax amino protease family 178062 7681927 SPP_0213 Streptococcus pneumoniae P1031 caax amino protease family YP_002737438.1 177385 D 488223 CDS YP_002737439.1 225855928 7681449 178074..178739 1 NC_012467.1 identified by match to protein family HMM PF02517; caax amino protease family 178739 7681449 SPP_0214 Streptococcus pneumoniae P1031 caax amino protease family YP_002737439.1 178074 D 488223 CDS YP_002737440.1 225855929 7681189 178811..180037 1 NC_012467.1 transporter, major facilitator family protein 180037 7681189 SPP_0215 Streptococcus pneumoniae P1031 transporter, major facilitator family protein YP_002737440.1 178811 D 488223 CDS YP_002737441.1 225855930 7682542 180491..181105 1 NC_012467.1 identified by match to protein family HMM PF03591; AzlC family protein 181105 7682542 SPP_0216 Streptococcus pneumoniae P1031 AzlC family protein YP_002737441.1 180491 D 488223 CDS YP_002737442.1 225855931 7680866 181209..182039 1 NC_012467.1 identified by match to protein family HMM PF00497; amino acid ABC transporter substrate-binding protein 182039 7680866 SPP_0217 Streptococcus pneumoniae P1031 amino acid ABC transporter substrate-binding protein YP_002737442.1 181209 D 488223 CDS YP_002737443.1 225855932 7682742 182193..183047 1 NC_012467.1 identified by match to protein family HMM PF03180; lipoprotein 183047 7682742 SPP_0218 Streptococcus pneumoniae P1031 lipoprotein YP_002737443.1 182193 D 488223 CDS YP_002737444.1 225855933 7681768 183147..184520 1 NC_012467.1 identified by match to protein family HMM PF01546; match to protein family HMM PF07687; acetylornithine deacetylase/succinyl-diaminopimelate desuccinylase 184520 7681768 SPP_0219 Streptococcus pneumoniae P1031 acetylornithine deacetylase/succinyl-diaminopimelate desuccinylase YP_002737444.1 183147 D 488223 CDS YP_002737445.1 225855934 7681175 184513..185574 1 NC_012467.1 identified by match to protein family HMM PF00005; methionine import ATP-binding protein MetN 185574 7681175 SPP_0220 Streptococcus pneumoniae P1031 methionine import ATP-binding protein MetN YP_002737445.1 184513 D 488223 CDS YP_002737446.1 225855935 7681852 185576..186268 1 NC_012467.1 identified by match to protein family HMM PF00528; ABC transporter permease 186268 7681852 SPP_0221 Streptococcus pneumoniae P1031 ABC transporter permease YP_002737446.1 185576 D 488223 CDS YP_002737447.1 225855936 7682241 complement(186298..186867) 1 NC_012467.1 identified by match to protein family HMM TIGR02185; membrane-bound protein 186867 7682241 SPP_0222 Streptococcus pneumoniae P1031 membrane-bound protein YP_002737447.1 186298 R 488223 CDS YP_002737448.1 225855937 7682239 187002..187616 1 NC_012467.1 identified by match to protein family HMM PF04854; hypothetical protein 187616 7682239 SPP_0223 Streptococcus pneumoniae P1031 hypothetical protein YP_002737448.1 187002 D 488223 CDS YP_002737449.1 225855938 7682438 187666..189264 1 NC_012467.1 identified by match to protein family HMM PF00672; match to protein family HMM PF02518; match to protein family HMM PF06580; sensor histidine kinase, putative 189264 7682438 SPP_0224 Streptococcus pneumoniae P1031 sensor histidine kinase, putative YP_002737449.1 187666 D 488223 CDS YP_002737450.1 225855939 7681920 189276..190562 1 NC_012467.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00165; response regulator 190562 7681920 SPP_0225 Streptococcus pneumoniae P1031 response regulator YP_002737450.1 189276 D 488223 CDS YP_002737451.1 225855940 7682442 190614..191147 1 NC_012467.1 hypothetical protein 191147 7682442 SPP_0226 Streptococcus pneumoniae P1031 hypothetical protein YP_002737451.1 190614 D 488223 CDS YP_002737452.1 225855941 7680994 191225..191695 1 NC_012467.1 has a stimulatory effect on the ribonucleotide reductase activity of NrdH with NrdEF; flavoprotein NrdI 191695 7680994 SPP_0227 Streptococcus pneumoniae P1031 flavoprotein NrdI YP_002737452.1 191225 D 488223 CDS YP_002737453.1 225855942 7680918 complement(191988..193250) 1 NC_012467.1 mn2+ and fe2+ transporter of the nramp family 193250 7680918 SPP_0228 Streptococcus pneumoniae P1031 mn2+ and fe2+ transporter of the nramp family YP_002737453.1 191988 R 488223 CDS YP_002737454.1 225855943 7681496 complement(193560..194018) 1 NC_012467.1 hypothetical protein 194018 7681496 SPP_0229 Streptococcus pneumoniae P1031 hypothetical protein YP_002737454.1 193560 R 488223 CDS YP_002737455.1 225855944 7682361 complement(194015..194455) 1 NC_012467.1 identified by match to protein family HMM PF04397; response regulator of the LytR/AlgR family 194455 7682361 SPP_0230 Streptococcus pneumoniae P1031 response regulator of the LytR/AlgR family YP_002737455.1 194015 R 488223 CDS YP_002737456.1 225855945 7681353 194661..196610 1 NC_012467.1 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. Promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex; DNA mismatch repair protein 196610 mutL 7681353 mutL Streptococcus pneumoniae P1031 DNA mismatch repair protein YP_002737456.1 194661 D 488223 CDS YP_002737457.1 225855946 7681064 complement(196935..197402) 1 NC_012467.1 RibE; 6,7-diimethyl-8-ribityllumazine synthase; DMRL synthase; lumazine synthase; beta subunit of riboflavin synthase; condenses 5-amino-6-(1'-D)-ribityl-amino-2,4(1H,3H)-pyrimidinedione with L-3,4-dihydrohy-2-butanone-4-phosphate to generate 6,6-dimethyl-8-lumazine (DMRL); riboflavin synthase then uses 2 molecules of DMRL to produce riboflavin (vitamin B12); involved in the last steps of riboflavin biosynthesis; forms a 60mer (icosahedral shell) in both Bacillus subtilis and Escherichia coli; in Bacillus subtilis this 60mer is associated with the riboflavin synthase subunit (alpha) while in Escherichia coli it is not; 6,7-dimethyl-8-ribityllumazine synthase 197402 ribH 7681064 ribH Streptococcus pneumoniae P1031 6,7-dimethyl-8-ribityllumazine synthase YP_002737457.1 196935 R 488223 CDS YP_002737458.1 225855947 7682783 complement(197403..198608) 1 NC_012467.1 identified by match to protein family HMM PF00925; match to protein family HMM PF00926; match to protein family HMM TIGR00505; match to protein family HMM TIGR00506; riboflavin biosynthesis protein ribAB 198608 7682783 SPP_0233 Streptococcus pneumoniae P1031 riboflavin biosynthesis protein ribAB YP_002737458.1 197403 R 488223 CDS YP_002737459.1 225855948 7681824 complement(198628..199263) 1 NC_012467.1 catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine; riboflavin synthase subunit alpha 199263 ribE 7681824 ribE Streptococcus pneumoniae P1031 riboflavin synthase subunit alpha YP_002737459.1 198628 R 488223 CDS YP_002737460.1 225855949 7682794 complement(199248..200348) 1 NC_012467.1 identified by match to protein family HMM PF00383; match to protein family HMM PF01872; match to protein family HMM TIGR00227; match to protein family HMM TIGR00326; riboflavin biosynthesis protein RibD 200348 ribD 7682794 ribD Streptococcus pneumoniae P1031 riboflavin biosynthesis protein RibD YP_002737460.1 199248 R 488223 CDS YP_002737461.1 225855950 7681712 200753..201346 1 NC_012467.1 plays an essential role in ATP-dependent branch migration of the Holliday junction; Holliday junction DNA helicase RuvA 201346 ruvA 7681712 ruvA Streptococcus pneumoniae P1031 Holliday junction DNA helicase RuvA YP_002737461.1 200753 D 488223 CDS YP_002737462.1 225855951 7682128 201356..201919 1 NC_012467.1 identified by match to protein family HMM PF03352; DNA-3-methyladenine glycosylase 1 201919 7682128 SPP_0237 Streptococcus pneumoniae P1031 DNA-3-methyladenine glycosylase 1 YP_002737462.1 201356 D 488223 CDS YP_002737463.1 225855952 7681919 201916..202593 1 NC_012467.1 identified by match to protein family HMM PF02517; caax amino protease family 202593 7681919 SPP_0238 Streptococcus pneumoniae P1031 caax amino protease family YP_002737463.1 201916 D 488223 CDS YP_002737464.1 225855953 7682295 complement(202730..203761) 1 NC_012467.1 identified by match to protein family HMM PF02016; MccC family protein 203761 7682295 SPP_0239 Streptococcus pneumoniae P1031 MccC family protein YP_002737464.1 202730 R 488223 CDS YP_002737465.1 225855954 7681045 complement(204016..204699) 1 NC_012467.1 identified by match to protein family HMM PF06570; hypothetical protein 204699 7681045 SPP_0240 Streptococcus pneumoniae P1031 hypothetical protein YP_002737465.1 204016 R 488223 CDS YP_002737466.1 225855955 7681810 complement(204711..205655) 1 NC_012467.1 identified by match to protein family HMM PF01544; magnesium and cobalt transporter 205655 7681810 SPP_0241 Streptococcus pneumoniae P1031 magnesium and cobalt transporter YP_002737466.1 204711 R 488223 CDS YP_002737467.1 225855956 7681047 205787..208618 1 NC_012467.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate; excinuclease ABC subunit A 208618 uvrA 7681047 uvrA Streptococcus pneumoniae P1031 excinuclease ABC subunit A YP_002737467.1 205787 D 488223 CDS YP_002737468.1 225855957 7680917 208611..209672 1 NC_012467.1 identified by match to protein family HMM PF00557; match to protein family HMM PF01321; Xaa-Pro dipeptidase 209672 7680917 SPP_0243 Streptococcus pneumoniae P1031 Xaa-Pro dipeptidase YP_002737468.1 208611 D 488223 CDS YP_002737469.1 225855958 7681639 209804..210202 1 NC_012467.1 the anti-alpha factor Spx interacts with RNA polymerase alpha subunit C-terminal domain in a region that interacts with the sigma 70 subunit and may interfere with activation of promoters; in Bacillus subtilis this protein is a substrate for ClpXP protease; blocks transcription of the competence regulatory gene encoded by the srf operon; regulates a number of genes involved in thiol homeostasis including trxA and trxB; monomeric member of ArsC family of proteins; does not bind DNA; contains a disulfide bond between C10 and C13 which may sense disulfide stress; transcriptional regulator Spx 210202 spxA 7681639 spxA Streptococcus pneumoniae P1031 transcriptional regulator Spx YP_002737469.1 209804 D 488223 CDS YP_002737470.1 225855959 7681864 210268..210837 1 NC_012467.1 lipoprotein, putative 210837 7681864 SPP_0245 Streptococcus pneumoniae P1031 lipoprotein, putative YP_002737470.1 210268 D 488223 CDS YP_002737471.1 225855960 7682136 210924..211190 1 NC_012467.1 identified by match to protein family HMM PF06135; hypothetical protein 211190 7682136 SPP_0246 Streptococcus pneumoniae P1031 hypothetical protein YP_002737471.1 210924 D 488223 CDS YP_002737472.1 225855961 7682555 211194..211613 1 NC_012467.1 similar to RuvC resolvase with substantial differences; NMR structural information suggests this protein is monomeric; unknown cellular function; Holliday junction resolvase-like protein 211613 7682555 SPP_0247 Streptococcus pneumoniae P1031 Holliday junction resolvase-like protein YP_002737472.1 211194 D 488223 CDS YP_002737473.1 225855962 7682270 211629..211934 1 NC_012467.1 identified by match to protein family HMM PF06949; hypothetical protein 211934 7682270 SPP_0248 Streptococcus pneumoniae P1031 hypothetical protein YP_002737473.1 211629 D 488223 CDS YP_002737474.1 225855963 7682705 212240..213490 1 NC_012467.1 identified by match to protein family HMM PF02875; match to protein family HMM PF08245; match to protein family HMM TIGR01499; dihydrofolate:folylpolyglutamate synthetase 213490 7682705 SPP_0249 Streptococcus pneumoniae P1031 dihydrofolate:folylpolyglutamate synthetase YP_002737474.1 212240 D 488223 CDS YP_002737475.1 225855964 7681964 213487..214029 1 NC_012467.1 hypothetical protein 214029 7681964 SPP_0250 Streptococcus pneumoniae P1031 hypothetical protein YP_002737475.1 213487 D 488223 CDS YP_002737476.1 225855965 7682000 214175..215707 1 NC_012467.1 identified by match to protein family HMM PF00614; cardiolipin synthase 215707 7682000 SPP_0251 Streptococcus pneumoniae P1031 cardiolipin synthase YP_002737476.1 214175 D 488223 CDS YP_002737477.1 225855966 7681568 215785..215928 1 NC_012467.1 hypothetical protein 215928 7681568 SPP_0252 Streptococcus pneumoniae P1031 hypothetical protein YP_002737477.1 215785 D 488223 CDS YP_002737478.1 225855967 7681388 215965..217503 1 NC_012467.1 competence-induced protein Ccs4 217503 7681388 SPP_0253 Streptococcus pneumoniae P1031 competence-induced protein Ccs4 YP_002737478.1 215965 D 488223 CDS YP_002737479.1 225855968 7681894 217617..219830 1 NC_012467.1 Catalyzes the reduction of nucleoside 5'-triphosphates to 2'-deoxynucleoside 5'-triphosphates; anaerobic ribonucleoside triphosphate reductase 219830 nrdD 7681894 nrdD Streptococcus pneumoniae P1031 anaerobic ribonucleoside triphosphate reductase YP_002737479.1 217617 D 488223 CDS YP_002737480.1 225855969 7681525 219842..219982 1 NC_012467.1 hypothetical protein 219982 7681525 SPP_0255 Streptococcus pneumoniae P1031 hypothetical protein YP_002737480.1 219842 D 488223 CDS YP_002737481.1 225855970 7681265 220026..220532 1 NC_012467.1 identified by match to protein family HMM PF00583; acetyltransferase, gnat family 220532 7681265 SPP_0256 Streptococcus pneumoniae P1031 acetyltransferase, gnat family YP_002737481.1 220026 D 488223 CDS YP_002737482.1 225855971 7681808 220525..221115 1 NC_012467.1 identified by match to protein family HMM TIGR02491; anaerobic ribonucleoside-triphosphate reductase activating protein 221115 nrdG 7681808 nrdG Streptococcus pneumoniae P1031 anaerobic ribonucleoside-triphosphate reductase activating protein YP_002737482.1 220525 D 488223 CDS YP_002737483.1 225855972 7681776 221112..221729 1 NC_012467.1 identified by match to protein family HMM PF00485; phosphoribulokinase / Uridine kinase family 221729 7681776 SPP_0258 Streptococcus pneumoniae P1031 phosphoribulokinase / Uridine kinase family YP_002737483.1 221112 D 488223 CDS YP_002737484.1 225855973 7681326 221984..222292 1 NC_012467.1 NusE; involved in assembly of the 30S subunit; in the ribosome, this protein is involved in the binding of tRNA; in Escherichia coli this protein was also found to be involved in transcription antitermination; NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination; binding of NusB/S10 to boxA nucleates assembly of the antitermination complex; 30S ribosomal protein S10 222292 rpsJ 7681326 rpsJ Streptococcus pneumoniae P1031 30S ribosomal protein S10 YP_002737484.1 221984 D 488223 CDS YP_002737485.1 225855974 7681177 222509..223135 1 NC_012467.1 binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin; 50S ribosomal protein L3 223135 rplC 7681177 rplC Streptococcus pneumoniae P1031 50S ribosomal protein L3 YP_002737485.1 222509 D 488223 CDS YP_002737486.1 225855975 7682748 223160..223783 1 NC_012467.1 L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA; 50S ribosomal protein L4 223783 rplD 7682748 rplD Streptococcus pneumoniae P1031 50S ribosomal protein L4 YP_002737486.1 223160 D 488223 CDS YP_002737487.1 225855976 7682527 223783..224079 1 NC_012467.1 binds third domain of 23S rRNA and protein L29; part of exit tunnel; 50S ribosomal protein L23 224079 rplW 7682527 rplW Streptococcus pneumoniae P1031 50S ribosomal protein L23 YP_002737487.1 223783 D 488223 CDS YP_002737488.1 225855977 7681156 224097..224930 1 NC_012467.1 one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation; 50S ribosomal protein L2 224930 rplB 7681156 rplB Streptococcus pneumoniae P1031 50S ribosomal protein L2 YP_002737488.1 224097 D 488223 CDS YP_002737489.1 225855978 7680699 225034..225315 1 NC_012467.1 protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA; 30S ribosomal protein S19 225315 rpsS 7680699 rpsS Streptococcus pneumoniae P1031 30S ribosomal protein S19 YP_002737489.1 225034 D 488223 CDS YP_002737490.1 225855979 7682341 225327..225671 1 NC_012467.1 binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center; 50S ribosomal protein L22 225671 rplV 7682341 rplV Streptococcus pneumoniae P1031 50S ribosomal protein L22 YP_002737490.1 225327 D 488223 CDS YP_002737491.1 225855980 7680998 225684..226337 1 NC_012467.1 forms a complex with S10 and S14; binds the lower part of the 30S subunit head and the mRNA in the complete ribosome to position it for translation; 30S ribosomal protein S3 226337 rpsC 7680998 rpsC Streptococcus pneumoniae P1031 30S ribosomal protein S3 YP_002737491.1 225684 D 488223 CDS YP_002737492.1 225855981 7680783 226341..226754 1 NC_012467.1 located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e; 50S ribosomal protein L16 226754 rplP 7680783 rplP Streptococcus pneumoniae P1031 50S ribosomal protein L16 YP_002737492.1 226341 D 488223 CDS YP_002737493.1 225855982 7681657 226764..226970 1 NC_012467.1 one of the stabilizing components for the large ribosomal subunit; 50S ribosomal protein L29 226970 rpmC 7681657 rpmC Streptococcus pneumoniae P1031 50S ribosomal protein L29 YP_002737493.1 226764 D 488223 CDS YP_002737494.1 225855983 7681617 226995..227255 1 NC_012467.1 primary binding protein; helps mediate assembly; involved in translation fidelity; 30S ribosomal protein S17 227255 rpsQ 7681617 rpsQ Streptococcus pneumoniae P1031 30S ribosomal protein S17 YP_002737494.1 226995 D 488223 CDS YP_002737495.1 225855984 7681648 227281..227649 1 NC_012467.1 binds to the 23S rRNA between the centers for peptidyl transferase and GTPase; 50S ribosomal protein L14 227649 rplN 7681648 rplN Streptococcus pneumoniae P1031 50S ribosomal protein L14 YP_002737495.1 227281 D 488223 CDS YP_002737496.1 225855985 7681845 227727..228032 1 NC_012467.1 assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel; 50S ribosomal protein L24 228032 rplX 7681845 rplX Streptococcus pneumoniae P1031 50S ribosomal protein L24 YP_002737496.1 227727 D 488223 CDS YP_002737497.1 225855986 7682498 228056..228598 1 NC_012467.1 part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13; 50S ribosomal protein L5 228598 rplE 7682498 rplE Streptococcus pneumoniae P1031 50S ribosomal protein L5 YP_002737497.1 228056 D 488223 CDS YP_002737498.1 225855987 7682382 228616..228885 1 NC_012467.1 located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group do not appear to have the zinc-binding motif; 30S ribosomal protein S14 228885 rpsN 7682382 rpsN Streptococcus pneumoniae P1031 30S ribosomal protein S14 YP_002737498.1 228616 D 488223 CDS YP_002737499.1 225855988 7680818 229170..229568 1 NC_012467.1 binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; 30S ribosomal protein S8 229568 rpsH 7680818 rpsH Streptococcus pneumoniae P1031 30S ribosomal protein S8 YP_002737499.1 229170 D 488223 CDS YP_002737500.1 225855989 7680862 229760..230296 1 NC_012467.1 ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance; 50S ribosomal protein L6 230296 rplF 7680862 rplF Streptococcus pneumoniae P1031 50S ribosomal protein L6 YP_002737500.1 229760 D 488223 CDS YP_002737501.1 225855990 7680956 230380..230736 1 NC_012467.1 binds 5S rRNA along with protein L5 and L25; 50S ribosomal protein L18 230736 rplR 7680956 rplR Streptococcus pneumoniae P1031 50S ribosomal protein L18 YP_002737501.1 230380 D 488223 CDS YP_002737502.1 225855991 7680999 230754..231248 1 NC_012467.1 located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance; 30S ribosomal protein S5 231248 rpsE 7680999 rpsE Streptococcus pneumoniae P1031 30S ribosomal protein S5 YP_002737502.1 230754 D 488223 CDS YP_002737503.1 225855992 7681076 231262..231444 1 NC_012467.1 L30 binds domain II of the 23S rRNA and the 5S rRNA; similar to eukaryotic protein L7; 50S ribosomal protein L30 231444 rpmD 7681076 rpmD Streptococcus pneumoniae P1031 50S ribosomal protein L30 YP_002737503.1 231262 D 488223 CDS YP_002737504.1 225855993 7681885 231589..232029 1 NC_012467.1 late assembly protein; 50S ribosomal protein L15 232029 rplO 7681885 rplO Streptococcus pneumoniae P1031 50S ribosomal protein L15 YP_002737504.1 231589 D 488223 CDS YP_002737505.1 225855994 7682853 232042..233352 1 NC_012467.1 forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase; preprotein translocase subunit SecY 233352 secY 7682853 secY Streptococcus pneumoniae P1031 preprotein translocase subunit SecY YP_002737505.1 232042 D 488223 CDS YP_002737506.1 225855995 7681184 233503..234141 1 NC_012467.1 essential enzyme that recycles AMP in active cells; converts ATP and AMP to two molecules of ADP; adenylate kinase 234141 adk 7681184 adk Streptococcus pneumoniae P1031 adenylate kinase YP_002737506.1 233503 D 488223 CDS YP_002737507.1 225855996 7682595 234258..234476 1 NC_012467.1 stimulates the activities of the other two initiation factors, IF-2 and IF-3; translation initiation factor IF-1 234476 infA 7682595 infA Streptococcus pneumoniae P1031 translation initiation factor IF-1 YP_002737507.1 234258 D 488223 CDS YP_002737508.1 225855997 7682871 234501..234617 1 NC_012467.1 smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group have the motif; 50S ribosomal protein L36 234617 rpmJ 7682871 rpmJ Streptococcus pneumoniae P1031 50S ribosomal protein L36 YP_002737508.1 234501 D 488223 CDS YP_002737509.1 225855998 7680946 234635..235000 1 NC_012467.1 located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA; 30S ribosomal protein S13 235000 rpsM 7680946 rpsM Streptococcus pneumoniae P1031 30S ribosomal protein S13 YP_002737509.1 234635 D 488223 CDS YP_002737510.1 225855999 7681755 235018..235401 1 NC_012467.1 located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3; 30S ribosomal protein S11 235401 rpsK 7681755 rpsK Streptococcus pneumoniae P1031 30S ribosomal protein S11 YP_002737510.1 235018 D 488223 CDS YP_002737511.1 225856000 7681428 235444..236379 1 NC_012467.1 catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme; DNA-directed RNA polymerase subunit alpha 236379 rpoA 7681428 rpoA Streptococcus pneumoniae P1031 DNA-directed RNA polymerase subunit alpha YP_002737511.1 235444 D 488223 CDS YP_002737512.1 225856001 7682855 236391..236777 1 NC_012467.1 is a component of the macrolide binding site in the peptidyl transferase center; 50S ribosomal protein L17 236777 rplQ 7682855 rplQ Streptococcus pneumoniae P1031 50S ribosomal protein L17 YP_002737512.1 236391 D 488223 CDS YP_002737513.1 225856002 7682386 237042..237308 1 NC_012467.1 ACT domain-containing protein; hypothetical protein 237308 7682386 SPP_0288 Streptococcus pneumoniae P1031 hypothetical protein YP_002737513.1 237042 D 488223 CDS YP_002737514.1 225856003 7681464 237318..238655 1 NC_012467.1 identified by match to protein family HMM PF05167; hypothetical protein 238655 7681464 SPP_0289 Streptococcus pneumoniae P1031 hypothetical protein YP_002737514.1 237318 D 488223 CDS YP_002737515.1 225856004 7680871 238899..239591 1 NC_012467.1 identified by match to protein family HMM PF00300; phosphoglycerate mutase family protein 239591 7680871 SPP_0290 Streptococcus pneumoniae P1031 phosphoglycerate mutase family protein YP_002737515.1 238899 D 488223 CDS YP_002737516.1 225856005 7681247 complement(244127..244903) 1 NC_012467.1 identified by match to protein family HMM PF04055; match to protein family HMM TIGR02494; pyruvate formate-lyase 3 244903 7681247 SPP_0297 Streptococcus pneumoniae P1031 pyruvate formate-lyase 3 YP_002737516.1 244127 R 488223 CDS YP_002737517.1 225856006 7682342 245025..245771 1 NC_012467.1 identified by match to protein family HMM PF00455; match to protein family HMM PF08220; match to protein family HMM PF08279; putative HTH-type transcriptional regulator YciT 245771 7682342 SPP_0298 Streptococcus pneumoniae P1031 putative HTH-type transcriptional regulator YciT YP_002737517.1 245025 D 488223 CDS YP_002737518.1 225856007 7682679 245784..246764 1 NC_012467.1 identified by match to protein family HMM PF04198; transcriptional regulator 246764 7682679 SPP_0299 Streptococcus pneumoniae P1031 transcriptional regulator YP_002737518.1 245784 D 488223 CDS YP_002737519.1 225856008 7681129 246959..247279 1 NC_012467.1 identified by match to protein family HMM PF02255; phosphotransferase system sugar-specific eiia component 247279 7681129 SPP_0300 Streptococcus pneumoniae P1031 phosphotransferase system sugar-specific eiia component YP_002737519.1 246959 D 488223 CDS YP_002737520.1 225856009 7680903 247325..247633 1 NC_012467.1 identified by match to protein family HMM PF02302; phosphotransferase system sugar-specific eiib component 247633 7680903 SPP_0301 Streptococcus pneumoniae P1031 phosphotransferase system sugar-specific eiib component YP_002737520.1 247325 D 488223 CDS YP_002737521.1 225856010 7682861 247650..248948 1 NC_012467.1 identified by match to protein family HMM PF02378; match to protein family HMM TIGR00410; lichenan permease iic component (pts system lichenan-specific eiiccomponent) (eiic-lic) 248948 7682861 SPP_0302 Streptococcus pneumoniae P1031 lichenan permease iic component (pts system lichenan-specific eiiccomponent) (eiic-lic) YP_002737521.1 247650 D 488223 CDS YP_002737522.1 225856011 7681826 249099..251537 1 NC_012467.1 identified by match to protein family HMM PF01228; match to protein family HMM PF02901; match to protein family HMM TIGR01774; pyruvate formate-lyase 251537 7681826 SPP_0303 Streptococcus pneumoniae P1031 pyruvate formate-lyase YP_002737522.1 249099 D 488223 CDS YP_002737523.1 225856012 7681780 251556..252224 1 NC_012467.1 similar to transaldolase from Escherichia coli; many organisms have multiple copies; fructose-6-phosphate aldolase 252224 7681780 SPP_0304 Streptococcus pneumoniae P1031 fructose-6-phosphate aldolase YP_002737523.1 251556 D 488223 CDS YP_002737524.1 225856013 7681684 252242..253330 1 NC_012467.1 forms dimers and octamers; involved in conversion of glycerol to dihydroxy-acetone; glycerol dehydrogenase 253330 gldA 7681684 gldA Streptococcus pneumoniae P1031 glycerol dehydrogenase YP_002737524.1 252242 D 488223 CDS YP_002737525.1 225856014 7682047 253785..256286 1 NC_012467.1 leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase; leucyl-tRNA synthetase 256286 leuS 7682047 leuS Streptococcus pneumoniae P1031 leucyl-tRNA synthetase YP_002737525.1 253785 D 488223 CDS YP_002737526.1 225856015 7681123 256480..257175 1 NC_012467.1 identified by match to protein family HMM PF00583; acetyltransferase, gnat family 257175 7681123 SPP_0307 Streptococcus pneumoniae P1031 acetyltransferase, gnat family YP_002737526.1 256480 D 488223 CDS YP_002737527.1 225856016 7681577 257187..257603 1 NC_012467.1 identified by match to protein family HMM PF00583; acetyltransferase, gnat family 257603 7681577 SPP_0308 Streptococcus pneumoniae P1031 acetyltransferase, gnat family YP_002737527.1 257187 D 488223 CDS YP_002737528.1 225856017 7681381 258644..259642 1 NC_012467.1 promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration; Holliday junction DNA helicase RuvB 259642 ruvB 7681381 ruvB Streptococcus pneumoniae P1031 Holliday junction DNA helicase RuvB YP_002737528.1 258644 D 488223 CDS YP_002737529.1 225856018 7681555 259623..260195 1 NC_012467.1 identified by match to protein family HMM PF06042; hypothetical protein 260195 7681555 SPP_0310 Streptococcus pneumoniae P1031 hypothetical protein YP_002737529.1 259623 D 488223 CDS YP_002737530.1 225856019 7682476 260426..261184 1 NC_012467.1 catalyzes the formation of undecaprenyl pyrophosphate from isopentenyl pyrophosphate; UDP pyrophosphate synthase 261184 uppS 7682476 uppS Streptococcus pneumoniae P1031 UDP pyrophosphate synthase YP_002737530.1 260426 D 488223 CDS YP_002737531.1 225856020 7681799 261193..261996 1 NC_012467.1 identified by match to protein family HMM PF01148; phosphatidate cytidylyltransferase 261996 cdsA 7681799 cdsA Streptococcus pneumoniae P1031 phosphatidate cytidylyltransferase YP_002737531.1 261193 D 488223 CDS YP_002737532.1 225856021 7681276 262018..263277 1 NC_012467.1 identified by match to protein family HMM PF02163; match to protein family HMM TIGR00054; RIP metalloprotease RseP 263277 rseP 7681276 rseP Streptococcus pneumoniae P1031 RIP metalloprotease RseP YP_002737532.1 262018 D 488223 CDS YP_002737533.1 225856022 7681242 263290..265143 1 NC_012467.1 catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro); prolyl-tRNA synthetase 265143 proS 7681242 proS Streptococcus pneumoniae P1031 prolyl-tRNA synthetase YP_002737533.1 263290 D 488223 CDS YP_002737534.1 225856023 7681886 265242..266621 1 NC_012467.1 identified by match to protein family HMM PF00232; 6-phospho-beta-glucosidase 266621 7681886 SPP_0315 Streptococcus pneumoniae P1031 6-phospho-beta-glucosidase YP_002737534.1 265242 D 488223 CDS YP_002737535.1 225856024 7682191 266814..268622 1 NC_012467.1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source; glucosamine--fructose-6-phosphate aminotransferase 268622 glmS 7682191 glmS Streptococcus pneumoniae P1031 glucosamine--fructose-6-phosphate aminotransferase YP_002737535.1 266814 D 488223 CDS YP_002737536.1 225856025 7681268 complement(268634..268837) 1 NC_012467.1 chlorohydrolase 268837 7681268 SPP_0317 Streptococcus pneumoniae P1031 chlorohydrolase YP_002737536.1 268634 R 488223 CDS YP_002737537.1 225856026 7681735 268894..269943 1 NC_012467.1 identified by match to protein family HMM PF00296; oxidoreductase 269943 7681735 SPP_0318 Streptococcus pneumoniae P1031 oxidoreductase YP_002737537.1 268894 D 488223 CDS YP_002737538.1 225856027 7681230 complement(270043..273813) 1 NC_012467.1 identified by match to protein family HMM PF00128; match to protein family HMM PF00746; match to protein family HMM PF02922; match to protein family HMM PF03714; match to protein family HMM PF04650; match to protein family HMM TIGR01167; match to protein family HMM TIGR01168; match to protein family HMM TIGR02102; pullulanase, extracellular 273813 7681230 SPP_0319 Streptococcus pneumoniae P1031 pullulanase, extracellular YP_002737538.1 270043 R 488223 CDS YP_002737539.1 225856028 7682402 274230..274643 1 NC_012467.1 interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance; 30S ribosomal protein S12 274643 rpsL 7682402 rpsL Streptococcus pneumoniae P1031 30S ribosomal protein S12 YP_002737539.1 274230 D 488223 CDS YP_002737540.1 225856029 7682739 274663..275133 1 NC_012467.1 binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit; 30S ribosomal protein S7 275133 rpsG 7682739 rpsG Streptococcus pneumoniae P1031 30S ribosomal protein S7 YP_002737540.1 274663 D 488223 CDS YP_002737541.1 225856030 7681569 275558..277639 1 NC_012467.1 EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene; elongation factor G 277639 fusA 7681569 fusA Streptococcus pneumoniae P1031 elongation factor G YP_002737541.1 275558 D 488223 CDS YP_002737542.1 225856031 7681654 277743..282134 1 NC_012467.1 catalyzes DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time; required for leading strand synthesis; PolC exhibits 3' to 5' exonuclease activity; DNA polymerase III PolC 282134 polC 7681654 polC Streptococcus pneumoniae P1031 DNA polymerase III PolC YP_002737542.1 277743 D 488223 CDS YP_002737543.1 225856032 7681719 282236..282499 1 NC_012467.1 identified by match to protein family HMM PF04221; match to protein family HMM TIGR02384; addiction module antitoxin, RelB/DinJ family 282499 7681719 SPP_0324 Streptococcus pneumoniae P1031 addiction module antitoxin, RelB/DinJ family YP_002737543.1 282236 D 488223 CDS YP_002737544.1 225856033 7681243 282492..282770 1 NC_012467.1 identified by match to protein family HMM PF05016; match to protein family HMM TIGR02385; DNA damage inducible protein 282770 7681243 SPP_0325 Streptococcus pneumoniae P1031 DNA damage inducible protein YP_002737544.1 282492 D 488223 CDS YP_002737545.1 225856034 7681235 282791..282943 1 NC_012467.1 hypothetical protein 282943 7681235 SPP_0326 Streptococcus pneumoniae P1031 hypothetical protein YP_002737545.1 282791 D 488223 CDS YP_002737546.1 225856035 7681092 282965..284206 1 NC_012467.1 identified by match to protein family HMM PF02073; aminopeptidase PepS 284206 7681092 SPP_0327 Streptococcus pneumoniae P1031 aminopeptidase PepS YP_002737546.1 282965 D 488223 CDS YP_002737547.1 225856036 7680842 284216..284446 1 NC_012467.1 identified by match to protein family HMM PF04226; integral membrane protein 284446 7680842 SPP_0328 Streptococcus pneumoniae P1031 integral membrane protein YP_002737547.1 284216 D 488223 CDS YP_002737548.1 225856037 7682638 284669..285391 1 NC_012467.1 identified by match to protein family HMM PF00849; match to protein family HMM PF01479; match to protein family HMM TIGR00093; ribosomal small subunit pseudouridine synthase A, putative 285391 7682638 SPP_0329 Streptococcus pneumoniae P1031 ribosomal small subunit pseudouridine synthase A, putative YP_002737548.1 284669 D 488223 CDS YP_002737549.1 225856038 7682717 285608..286942 1 NC_012467.1 identified by match to protein family HMM PF03051; aminopeptidase C (Bleomycin hydrolase) 286942 7682717 SPP_0330 Streptococcus pneumoniae P1031 aminopeptidase C (Bleomycin hydrolase) YP_002737549.1 285608 D 488223 CDS YP_002737550.1 225856039 7681367 complement(286998..287909) 1 NC_012467.1 identified by match to protein family HMM PF03613; match to protein family HMM TIGR00828; PTS system, mannose/fructose/sorbose family, IID component 287909 7681367 SPP_0331 Streptococcus pneumoniae P1031 PTS system, mannose/fructose/sorbose family, IID component YP_002737550.1 286998 R 488223 CDS YP_002737551.1 225856040 7681073 complement(287933..288736) 1 NC_012467.1 identified by match to protein family HMM PF03609; PTS system sorbose-specific IIC component 288736 7681073 SPP_0332 Streptococcus pneumoniae P1031 PTS system sorbose-specific IIC component YP_002737551.1 287933 R 488223 CDS YP_002737552.1 225856041 7681576 complement(288764..289753) 1 NC_012467.1 identified by match to protein family HMM PF03610; match to protein family HMM PF03830; mannose-specific phosphotransferase system component iiab 289753 7681576 SPP_0333 Streptococcus pneumoniae P1031 mannose-specific phosphotransferase system component iiab YP_002737552.1 288764 R 488223 CDS YP_002737553.1 225856042 7682235 complement(289986..291005) 1 NC_012467.1 similar to zinc-dependent eukaryotic ADH enzymes and distinct from fermentative ADHs; alcohol dehydrogenase 291005 7682235 SPP_0334 Streptococcus pneumoniae P1031 alcohol dehydrogenase YP_002737553.1 289986 R 488223 CDS YP_002737554.1 225856043 7682106 complement(291114..291260) 1 NC_012467.1 identified by glimmer; putative; hypothetical protein 291260 7682106 SPP_0335 Streptococcus pneumoniae P1031 hypothetical protein YP_002737554.1 291114 R 488223 CDS YP_002737555.1 225856044 7681660 complement(291344..292156) 1 NC_012467.1 identified by match to protein family HMM PF00702; match to protein family HMM PF05116; match to protein family HMM PF08282; match to protein family HMM TIGR00099; match to protein family HMM TIGR01484; Cof family protein 292156 7681660 SPP_0336 Streptococcus pneumoniae P1031 Cof family protein YP_002737555.1 291344 R 488223 CDS YP_002737556.1 225856045 7682283 292346..293764 1 NC_012467.1 identified by match to protein family HMM PF00860; xanthine/uracil permease family protein 293764 7682283 SPP_0337 Streptococcus pneumoniae P1031 xanthine/uracil permease family protein YP_002737556.1 292346 D 488223 CDS YP_002737557.1 225856046 7682779 293817..294524 1 NC_012467.1 identified by match to protein family HMM PF02517; caax amino protease family protein 294524 7682779 SPP_0338 Streptococcus pneumoniae P1031 caax amino protease family protein YP_002737557.1 293817 D 488223 CDS YP_002737558.1 225856047 7682158 294620..295600 1 NC_012467.1 identified by match to protein family HMM PF00809; match to protein family HMM TIGR01496; dihydropteroate synthase 295600 folP 7682158 folP Streptococcus pneumoniae P1031 dihydropteroate synthase YP_002737558.1 294620 D 488223 CDS YP_002737559.1 225856048 7681126 295602..296924 1 NC_012467.1 identified by match to protein family HMM PF02875; match to protein family HMM PF08245; match to protein family HMM TIGR01499; dihydrofolate synthetase 296924 7681126 SPP_0340 Streptococcus pneumoniae P1031 dihydrofolate synthetase YP_002737559.1 295602 D 488223 CDS YP_002737560.1 225856049 7681481 296905..297459 1 NC_012467.1 involved in the first step of tetrahydrofolate biosynthesis; catalyzes the formation of formate and 2-amino-4-hydroxy-6-(erythro-1,2, 3-trihydroxypropyl)dihydropteridine triphosphate from GTP and water; forms a homopolymer; GTP cyclohydrolase I 297459 folE 7681481 folE Streptococcus pneumoniae P1031 GTP cyclohydrolase I YP_002737560.1 296905 D 488223 CDS YP_002737561.1 225856050 7682842 297502..298314 1 NC_012467.1 identified by match to protein family HMM PF01288; match to protein family HMM PF02152; match to protein family HMM TIGR00525; match to protein family HMM TIGR00526; match to protein family HMM TIGR01498; bifunctional folate synthesis protein 298314 7682842 SPP_0342 Streptococcus pneumoniae P1031 bifunctional folate synthesis protein YP_002737561.1 297502 D 488223 CDS YP_002737562.1 225856051 7682203 complement(298359..298676) 1 NC_012467.1 hypothetical protein 298676 7682203 SPP_0343 Streptococcus pneumoniae P1031 hypothetical protein YP_002737562.1 298359 R 488223 CDS YP_002737563.1 225856052 7682447 299033..299479 1 NC_012467.1 in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit; 50S ribosomal protein L13 299479 rplM 7682447 rplM Streptococcus pneumoniae P1031 50S ribosomal protein L13 YP_002737563.1 299033 D 488223 CDS YP_002737564.1 225856053 7681933 299498..299890 1 NC_012467.1 forms a direct contact with the tRNA during translation; 30S ribosomal protein S9 299890 rpsI 7681933 rpsI Streptococcus pneumoniae P1031 30S ribosomal protein S9 YP_002737564.1 299498 D 488223 CDS YP_002737565.1 225856054 7682005 complement(300152..300574) 1 NC_012467.1 identified by match to protein family HMM PF00589; integrase/recombinase, phage integrase family 300574 7682005 SPP_0346 Streptococcus pneumoniae P1031 integrase/recombinase, phage integrase family YP_002737565.1 300152 R 488223 CDS YP_002737566.1 225856055 7681604 300721..300897 1 NC_012467.1 hypothetical protein 300897 7681604 SPP_0347 Streptococcus pneumoniae P1031 hypothetical protein YP_002737566.1 300721 D 488223 CDS YP_002737567.1 225856056 7682702 301299..303512 1 NC_012467.1 identified by match to protein family HMM PF01055; glycosyl hydrolase, family 31 303512 7682702 SPP_0348 Streptococcus pneumoniae P1031 glycosyl hydrolase, family 31 YP_002737567.1 301299 D 488223 CDS YP_002737568.1 225856057 7682141 complement(303734..304210) 1 NC_012467.1 identified by match to protein family HMM PF00255; peroxiredoxin Hyr1 (hydrogen peroxide resistanceprotein 1) (oxidant receptor peroxidase 1) (glutathione peroxidase 3)(phospholipid hydroperoxide glutathione peroxidase 3) (phgpx3) 304210 7682141 SPP_0349 Streptococcus pneumoniae P1031 peroxiredoxin Hyr1 (hydrogen peroxide resistanceprotein 1) (oxidant receptor peroxidase 1) (glutathione peroxidase 3)(phospholipid hydroperoxide glutathione peroxidase 3) (phgpx3) YP_002737568.1 303734 R 488223 CDS YP_002737569.1 225856058 7681333 304433..307636 1 NC_012467.1 identified by match to protein family HMM PF00746; match to protein family HMM PF02018; match to protein family HMM PF02278; match to protein family HMM PF02884; match to protein family HMM PF08124; match to protein family HMM TIGR01167; hyaluronate lyase 307636 7681333 SPP_0350 Streptococcus pneumoniae P1031 hyaluronate lyase YP_002737569.1 304433 D 488223 CDS YP_002737570.1 225856059 7681029 complement(308779..309408) 1 NC_012467.1 catalyzes the formation of pyruvate and glyoxylate from 4-hydroxy-2-oxoglutarate; or pyruvate and D-glyceraldehyde 3-phosphate from 2-dehydro-3-deoxy-D-glyconate 6-phosphate; keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase 309408 7681029 SPP_0352 Streptococcus pneumoniae P1031 keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase YP_002737570.1 308779 R 488223 CDS YP_002737571.1 225856060 7680868 complement(309418..310419) 1 NC_012467.1 carbohydrate kinase, PfkB family 310419 7680868 SPP_0353 Streptococcus pneumoniae P1031 carbohydrate kinase, PfkB family YP_002737571.1 309418 R 488223 CDS YP_002737572.1 225856061 7681606 complement(310450..311091) 1 NC_012467.1 identified by match to protein family HMM PF02502; hypothetical protein 311091 7681606 SPP_0354 Streptococcus pneumoniae P1031 hypothetical protein YP_002737572.1 310450 R 488223 CDS YP_002737573.1 225856062 7682691 complement(311110..311925) 1 NC_012467.1 Involved in the nonphosphorylative, ketogenic oxidation of glucose and oxidizes gluconate to 5-ketogluconate; gluconate 5-dehydrogenase 311925 7682691 SPP_0355 Streptococcus pneumoniae P1031 gluconate 5-dehydrogenase YP_002737573.1 311110 R 488223 CDS YP_002737574.1 225856063 7682095 312196..312630 1 NC_012467.1 identified by match to protein family HMM PF03610; phosphotransferase system sugar-specific EII component 312630 7682095 SPP_0356 Streptococcus pneumoniae P1031 phosphotransferase system sugar-specific EII component YP_002737574.1 312196 D 488223 CDS YP_002737575.1 225856064 7681425 312642..313832 1 NC_012467.1 identified by match to protein family HMM PF07470; unsaturated glucuronyl hydrolase (UGL) (Glycuronidase)(Unsaturated uronic acid hydrolase) (Glycosaminoglycan hydrolase) 313832 7681425 SPP_0357 Streptococcus pneumoniae P1031 unsaturated glucuronyl hydrolase (UGL) (Glycuronidase)(Unsaturated uronic acid hydrolase) (Glycosaminoglycan hydrolase) YP_002737575.1 312642 D 488223 CDS YP_002737576.1 225856065 7681211 313843..314334 1 NC_012467.1 identified by match to protein family HMM PF03830; N-acetylgalactosamine-specific phosphotransferase enzyme iib component2 (pts system n-acetylgalactosamine-specific eiibcomponent 2) (eiib-aga') 314334 7681211 SPP_0358 Streptococcus pneumoniae P1031 N-acetylgalactosamine-specific phosphotransferase enzyme iib component2 (pts system n-acetylgalactosamine-specific eiibcomponent 2) (eiib-aga') YP_002737576.1 313843 D 488223 CDS YP_002737577.1 225856066 7682516 314349..315128 1 NC_012467.1 identified by match to protein family HMM PF03609; phosphotransferase system sugar-specific EII component 315128 7682516 SPP_0359 Streptococcus pneumoniae P1031 phosphotransferase system sugar-specific EII component YP_002737577.1 314349 D 488223 CDS YP_002737578.1 225856067 7682255 315115..315933 1 NC_012467.1 identified by match to protein family HMM PF03613; PTS system, IID component 315933 7682255 SPP_0360 Streptococcus pneumoniae P1031 PTS system, IID component YP_002737578.1 315115 D 488223 CDS YP_002737579.1 225856068 7680680 315969..316226 1 NC_012467.1 preprotein translocase, YajC subunit 316226 7680680 SPP_0361 Streptococcus pneumoniae P1031 preprotein translocase, YajC subunit YP_002737579.1 315969 D 488223 CDS YP_002737580.1 225856069 7682286 316248..318149 1 NC_012467.1 identified by match to protein family HMM PF07940; oligohyaluronate lyase 318149 7682286 SPP_0362 Streptococcus pneumoniae P1031 oligohyaluronate lyase YP_002737580.1 316248 D 488223 CDS YP_002737581.1 225856070 7682570 318209..319210 1 NC_012467.1 identified by match to protein family HMM PF00356; match to protein family HMM PF00532; sugar binding transcriptional regulator RegR 319210 7682570 SPP_0363 Streptococcus pneumoniae P1031 sugar binding transcriptional regulator RegR YP_002737581.1 318209 D 488223 CDS YP_002737582.1 225856071 7681499 complement(319320..319655) 1 NC_012467.1 identified by glimmer; putative; hypothetical protein 319655 7681499 SPP_0364 Streptococcus pneumoniae P1031 hypothetical protein YP_002737582.1 319320 R 488223 CDS YP_002737583.1 225856072 7681385 complement(319666..319908) 1 NC_012467.1 identified by glimmer; putative; hypothetical protein 319908 7681385 SPP_0365 Streptococcus pneumoniae P1031 hypothetical protein YP_002737583.1 319666 R 488223 CDS YP_002737584.1 225856073 7682730 complement(319919..320461) 1 NC_012467.1 hypothetical protein 320461 7682730 SPP_0366 Streptococcus pneumoniae P1031 hypothetical protein YP_002737584.1 319919 R 488223 CDS YP_002737585.1 225856074 7681847 complement(320477..320671) 1 NC_012467.1 identified by match to protein family HMM PF01381; hypothetical protein 320671 7681847 SPP_0367 Streptococcus pneumoniae P1031 hypothetical protein YP_002737585.1 320477 R 488223 CDS YP_002737586.1 225856075 7682123 320837..321787 1 NC_012467.1 identified by match to protein family HMM PF01795; match to protein family HMM TIGR00006; S-adenosyl-methyltransferase MraW 321787 mraW 7682123 mraW Streptococcus pneumoniae P1031 S-adenosyl-methyltransferase MraW YP_002737586.1 320837 D 488223 CDS YP_002737587.1 225856076 7681970 321799..322116 1 NC_012467.1 identified by match to protein family HMM TIGR02209; cell division protein FtsL 322116 ftsL 7681970 ftsL Streptococcus pneumoniae P1031 cell division protein FtsL YP_002737587.1 321799 D 488223 CDS YP_002737588.1 225856077 7681634 322120..324372 1 NC_012467.1 identified by match to protein family HMM PF00905; match to protein family HMM PF03717; match to protein family HMM PF03793; penicillin-binding protein 2X 324372 7681634 SPP_0370 Streptococcus pneumoniae P1031 penicillin-binding protein 2X YP_002737588.1 322120 D 488223 CDS YP_002737589.1 225856078 7681685 324374..325354 1 NC_012467.1 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; phospho-N-acetylmuramoyl-pentapeptide- transferase 325354 mraY 7681685 mraY Streptococcus pneumoniae P1031 phospho-N-acetylmuramoyl-pentapeptide- transferase YP_002737589.1 324374 D 488223 CDS YP_002737590.1 225856079 7681471 325566..325682 1 NC_012467.1 identified by glimmer; putative; hypothetical protein 325682 7681471 SPP_0372 Streptococcus pneumoniae P1031 hypothetical protein YP_002737590.1 325566 D 488223 CDS YP_002737591.1 225856080 7682788 325963..328068 1 NC_012467.1 identified by match to protein family HMM PF00004; match to protein family HMM PF07724; match to protein family HMM PF07728; ATP-dependent Clp protease ATP-binding subunit ClpL 328068 7682788 SPP_0373 Streptococcus pneumoniae P1031 ATP-dependent Clp protease ATP-binding subunit ClpL YP_002737591.1 325963 D 488223 CDS YP_002737592.1 225856081 7680886 328506..328856 1 NC_012467.1 identified by match to protein family HMM PF08388; GBSi1, group II intron, maturase 328856 7680886 SPP_0374 Streptococcus pneumoniae P1031 GBSi1, group II intron, maturase YP_002737592.1 328506 D 488223 CDS YP_002737593.1 225856082 7680711 complement(328923..329405) 1 NC_012467.1 catalyzes the hydrolysis of S-ribosylhomocysteine to homocysteine and autoinducer-2; S-ribosylhomocysteinase 329405 luxS 7680711 luxS Streptococcus pneumoniae P1031 S-ribosylhomocysteinase YP_002737593.1 328923 R 488223 CDS YP_002737594.1 225856083 7682628 complement(329500..330984) 1 NC_012467.1 identified by match to protein family HMM PF08903; hypothetical protein 330984 7682628 SPP_0376 Streptococcus pneumoniae P1031 hypothetical protein YP_002737594.1 329500 R 488223 CDS YP_002737595.1 225856084 7682751 331137..332744 1 NC_012467.1 identified by match to protein family HMM PF00128; trehalose-6-phosphate hydrolase (Alpha,alpha-phosphotrehalase) 332744 7682751 SPP_0377 Streptococcus pneumoniae P1031 trehalose-6-phosphate hydrolase (Alpha,alpha-phosphotrehalase) YP_002737595.1 331137 D 488223 CDS YP_002737596.1 225856085 7682509 332903..333076 1 NC_012467.1 lipoprotein, putative 333076 7682509 SPP_0378 Streptococcus pneumoniae P1031 lipoprotein, putative YP_002737596.1 332903 D 488223 CDS YP_002737597.1 225856086 7681621 334773..334898 1 NC_012467.1 identified by glimmer; putative; hypothetical protein 334898 7681621 SPP_0381 Streptococcus pneumoniae P1031 hypothetical protein YP_002737597.1 334773 D 488223 CDS YP_002737598.1 225856087 7681774 complement(334994..335392) 1 NC_012467.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by match to protein family HMM PF01710; Spn1, transposase Orf1 335392 7681774 SPP_0382 Streptococcus pneumoniae P1031 Spn1, transposase Orf1 YP_002737598.1 334994 R 488223 CDS YP_002737599.1 225856088 7682144 335645..337090 1 NC_012467.1 identified by match to protein family HMM PF02916; match to protein family HMM PF03816; match to protein family HMM TIGR00350; integral membrane regulatory protein Wzg 337090 7682144 SPP_0383 Streptococcus pneumoniae P1031 integral membrane regulatory protein Wzg YP_002737599.1 335645 D 488223 CDS YP_002737600.1 225856089 7682657 337092..337823 1 NC_012467.1 identified by match to protein family HMM PF02811; tyrosine-protein phosphatase CpsB 337823 7682657 SPP_0384 Streptococcus pneumoniae P1031 tyrosine-protein phosphatase CpsB YP_002737600.1 337092 D 488223 CDS YP_002737601.1 225856090 7682373 337832..338524 1 NC_012467.1 identified by match to protein family HMM PF02706; match to protein family HMM TIGR01006; capsular polysaccharide biosynthesis protein Wzd 338524 7682373 SPP_0385 Streptococcus pneumoniae P1031 capsular polysaccharide biosynthesis protein Wzd YP_002737601.1 337832 D 488223 CDS YP_002737602.1 225856091 7680978 338534..339199 1 NC_012467.1 identified by match to protein family HMM TIGR01007; tyrosine-protein kinase CpsD 339199 7680978 SPP_0386 Streptococcus pneumoniae P1031 tyrosine-protein kinase CpsD YP_002737602.1 338534 D 488223 CDS YP_002737603.1 225856092 7681335 339340..340476 1 NC_012467.1 identified by match to protein family HMM PF00534; galacturonosyl transferase 340476 7681335 SPP_0387 Streptococcus pneumoniae P1031 galacturonosyl transferase YP_002737603.1 339340 D 488223 CDS YP_002737604.1 225856093 7680809 340469..341020 1 NC_012467.1 galacturonic acid acetylase 341020 7680809 SPP_0388 Streptococcus pneumoniae P1031 galacturonic acid acetylase YP_002737604.1 340469 D 488223 CDS YP_002737605.1 225856094 7682699 341017..342171 1 NC_012467.1 identified by match to protein family HMM PF00534; glycosyl transferase, group 1 family protein 342171 7682699 SPP_0389 Streptococcus pneumoniae P1031 glycosyl transferase, group 1 family protein YP_002737605.1 341017 D 488223 CDS YP_002737606.1 225856095 7680982 342288..343592 1 NC_012467.1 hypothetical protein 343592 7680982 SPP_0390 Streptococcus pneumoniae P1031 hypothetical protein YP_002737606.1 342288 D 488223 CDS YP_002737607.1 225856096 7682232 343778..344947 1 NC_012467.1 identified by match to protein family HMM PF01943; flippase Wzx 344947 7682232 SPP_0391 Streptococcus pneumoniae P1031 flippase Wzx YP_002737607.1 343778 D 488223 CDS YP_002737608.1 225856097 7682216 345015..346085 1 NC_012467.1 identified by match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF02719; match to protein family HMM PF04321; match to protein family HMM PF07993; UDP-glucuronate 5'-epimerase (UDP-glucuronic acidepimerase) 346085 7682216 SPP_0392 Streptococcus pneumoniae P1031 UDP-glucuronate 5'-epimerase (UDP-glucuronic acidepimerase) YP_002737608.1 345015 D 488223 CDS YP_002737609.1 225856098 7681133 346114..347346 1 NC_012467.1 identified by match to protein family HMM PF00984; match to protein family HMM PF01210; match to protein family HMM PF03720; match to protein family HMM PF03721; match to protein family HMM TIGR03026; UDP-glucose 6-dehydrogenase 347346 7681133 SPP_0393 Streptococcus pneumoniae P1031 UDP-glucose 6-dehydrogenase YP_002737609.1 346114 D 488223 CDS YP_002737610.1 225856099 7682376 347562..347744 1 NC_012467.1 identified by glimmer; putative; hypothetical protein 347744 7682376 SPP_0394 Streptococcus pneumoniae P1031 hypothetical protein YP_002737610.1 347562 D 488223 CDS YP_002737611.1 225856100 7682839 complement(348032..348382) 1 NC_012467.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop; transposase 348382 7682839 SPP_0395 Streptococcus pneumoniae P1031 transposase YP_002737611.1 348032 R 488223 CDS YP_002737612.1 225856101 7681694 349552..350409 1 NC_012467.1 identified by match to protein family HMM PF00483; match to protein family HMM TIGR01207; glucose-1-phosphate thymidylyltransferase 350409 rfbA 7681694 rfbA Streptococcus pneumoniae P1031 glucose-1-phosphate thymidylyltransferase YP_002737612.1 349552 D 488223 CDS YP_002737613.1 225856102 7681107 350410..351006 1 NC_012467.1 identified by match to protein family HMM PF00908; dTDP-4-dehydrorhamnose 3,5-epimerase 351006 7681107 SPP_0399 Streptococcus pneumoniae P1031 dTDP-4-dehydrorhamnose 3,5-epimerase YP_002737613.1 350410 D 488223 CDS YP_002737614.1 225856103 7681877 351016..352065 1 NC_012467.1 identified by match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF04321; match to protein family HMM PF07993; match to protein family HMM TIGR01181; dTDP-glucose 4,6-dehydratase 352065 rfbB 7681877 rfbB Streptococcus pneumoniae P1031 dTDP-glucose 4,6-dehydratase YP_002737614.1 351016 D 488223 CDS YP_002737615.1 225856104 7682055 353057..353491 1 NC_012467.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop; transposase 353491 7682055 SPP_0403 Streptococcus pneumoniae P1031 transposase YP_002737615.1 353057 D 488223 CDS YP_002737616.1 225856105 7682625 354409..356391 1 NC_012467.1 identified by match to protein family HMM PF00496; oligopeptide binding protein 356391 7682625 SPP_0405 Streptococcus pneumoniae P1031 oligopeptide binding protein YP_002737616.1 354409 D 488223 CDS YP_002737617.1 225856106 7682629 356692..361995 1 NC_012467.1 identified by match to protein family HMM PF00754; match to protein family HMM PF04650; match to protein family HMM TIGR01167; match to protein family HMM TIGR01168; endo-alpha-N-acetylgalactosaminidase 361995 7682629 SPP_0406 Streptococcus pneumoniae P1031 endo-alpha-N-acetylgalactosaminidase YP_002737617.1 356692 D 488223 CDS YP_002737618.1 225856107 7681731 complement(362162..364321) 1 NC_012467.1 identified by match to protein family HMM PF00905; match to protein family HMM PF00912; match to protein family HMM TIGR02074; penicillin-binding protein 1A 364321 7681731 SPP_0407 Streptococcus pneumoniae P1031 penicillin-binding protein 1A YP_002737618.1 362162 R 488223 CDS YP_002737619.1 225856108 7682045 complement(364318..364914) 1 NC_012467.1 functions in homologous recombination, DNA repair, and chromosome segregation; binds preferentially to three- and four-stranded DNA intermediates; introduces specific nick sites in four-stranded DNA substrates; functions similarly to Escherichia coli RuvC; Holliday junction-specific endonuclease 364914 recU 7682045 recU Streptococcus pneumoniae P1031 Holliday junction-specific endonuclease YP_002737619.1 364318 R 488223 CDS YP_002737620.1 225856109 7680840 364980..365507 1 NC_012467.1 identified by match to protein family HMM PF06908; hypothetical protein 365507 7680840 SPP_0409 Streptococcus pneumoniae P1031 hypothetical protein YP_002737620.1 364980 D 488223 CDS YP_002737621.1 225856110 7682526 365577..365906 1 NC_012467.1 identified by match to protein family HMM PF05103; cell division initiation protein 365906 7682526 SPP_0410 Streptococcus pneumoniae P1031 cell division initiation protein YP_002737621.1 365577 D 488223 CDS YP_002737622.1 225856111 7680714 366392..367549 1 NC_012467.1 identified by match to protein family HMM PF01170; methyltransferase 367549 7680714 SPP_0411 Streptococcus pneumoniae P1031 methyltransferase YP_002737622.1 366392 D 488223 CDS YP_002737623.1 225856112 7682024 367562..368956 1 NC_012467.1 hypothetical protein 368956 7682024 SPP_0412 Streptococcus pneumoniae P1031 hypothetical protein YP_002737623.1 367562 D 488223 CDS YP_002737624.1 225856113 7681838 369032..370456 1 NC_012467.1 catalyzes the formation of D-ribulose 5-phosphate from 6-phospho-D-gluconate; 6-phosphogluconate dehydrogenase 370456 gnd 7681838 gnd Streptococcus pneumoniae P1031 6-phosphogluconate dehydrogenase YP_002737624.1 369032 D 488223 CDS YP_002737625.1 225856114 7680688 370468..371157 1 NC_012467.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00486; DNA-binding response regulator 371157 7680688 SPP_0414 Streptococcus pneumoniae P1031 DNA-binding response regulator YP_002737625.1 370468 D 488223 CDS YP_002737626.1 225856115 7681217 371255..372274 1 NC_012467.1 identified by match to protein family HMM PF01473; choline-binding protein F 372274 7681217 SPP_0415 Streptococcus pneumoniae P1031 choline-binding protein F YP_002737626.1 371255 D 488223 CDS YP_002737627.1 225856116 7681950 complement(372392..373624) 1 NC_012467.1 identified by match to protein family HMM PF07690; transporter, major facilitator family protein 373624 7681950 SPP_0416 Streptococcus pneumoniae P1031 transporter, major facilitator family protein YP_002737627.1 372392 R 488223 CDS YP_002737628.1 225856117 7682111 375305..375484 1 NC_012467.1 identified by match to protein family HMM PF01473; choline binding protein J 375484 7682111 SPP_0418 Streptococcus pneumoniae P1031 choline binding protein J YP_002737628.1 375305 D 488223 CDS YP_002737629.1 225856118 7681825 375606..376484 1 NC_012467.1 identified by match to protein family HMM PF00288; match to protein family HMM PF08544; match to protein family HMM TIGR00549; mevalonate kinase 376484 mvk 7681825 mvk Streptococcus pneumoniae P1031 mevalonate kinase YP_002737629.1 375606 D 488223 CDS YP_002737630.1 225856119 7682419 376466..377419 1 NC_012467.1 identified by match to protein family HMM PF00288; match to protein family HMM PF08544; match to protein family HMM TIGR01240; diphosphomevalonate decarboxylase 377419 mvaD 7682419 mvaD Streptococcus pneumoniae P1031 diphosphomevalonate decarboxylase YP_002737630.1 376466 D 488223 CDS YP_002737631.1 225856120 7682368 377406..378413 1 NC_012467.1 identified by match to protein family HMM PF00288; match to protein family HMM PF08544; match to protein family HMM TIGR01220; phosphomevalonate kinase 378413 7682368 SPP_0421 Streptococcus pneumoniae P1031 phosphomevalonate kinase YP_002737631.1 377406 D 488223 CDS YP_002737632.1 225856121 7680928 378397..379407 1 NC_012467.1 catalyzes the isomerization of isopentenyl pyrophosphate to dimethylallyl diphosphate; isopentenyl pyrophosphate isomerase 379407 fni 7680928 fni Streptococcus pneumoniae P1031 isopentenyl pyrophosphate isomerase YP_002737632.1 378397 D 488223 CDS YP_002737633.1 225856122 7681038 379484..380182 1 NC_012467.1 hypothetical protein 380182 7681038 SPP_0423 Streptococcus pneumoniae P1031 hypothetical protein YP_002737633.1 379484 D 488223 CDS YP_002737634.1 225856123 7682615 380179..381174 1 NC_012467.1 identified by match to protein family HMM PF02518; match to protein family HMM PF07730; histidine kinase 381174 7682615 SPP_0424 Streptococcus pneumoniae P1031 histidine kinase YP_002737634.1 380179 D 488223 CDS YP_002737635.1 225856124 7682843 381188..381820 1 NC_012467.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00196; match to protein family HMM PF08281; response regulator 381820 7682843 SPP_0425 Streptococcus pneumoniae P1031 response regulator YP_002737635.1 381188 D 488223 CDS YP_002737636.1 225856125 7682732 382414..382590 1 NC_012467.1 DNA alkylation repair enzyme, truncation 382590 7682732 SPP_0428 Streptococcus pneumoniae P1031 DNA alkylation repair enzyme, truncation YP_002737636.1 382414 D 488223 CDS YP_002737637.1 225856126 7682052 382740..382979 1 NC_012467.1 hypothetical protein 382979 7682052 SPP_0429 Streptococcus pneumoniae P1031 hypothetical protein YP_002737637.1 382740 D 488223 CDS YP_002737638.1 225856127 7680847 382976..383653 1 NC_012467.1 identified by match to protein family HMM PF00089; choline binding protein G 383653 7680847 SPP_0430 Streptococcus pneumoniae P1031 choline binding protein G YP_002737638.1 382976 D 488223 CDS YP_002737639.1 225856128 7680684 383952..384344 1 NC_012467.1 integrase 384344 7680684 SPP_0431 Streptococcus pneumoniae P1031 integrase YP_002737639.1 383952 D 488223 CDS YP_002737640.1 225856129 7682285 384505..385788 1 NC_012467.1 Tig; RopA; peptidyl-prolyl cis/trans isomerase; promotes folding of newly synthesized proteins; binds ribosomal 50S subunit; forms a homodimer; trigger factor 385788 tig 7682285 tig Streptococcus pneumoniae P1031 trigger factor YP_002737640.1 384505 D 488223 CDS YP_002737641.1 225856130 7682608 complement(385836..388202) 1 NC_012467.1 identified by match to protein family HMM TIGR01448; helicase, RecD/TraA family 388202 7682608 SPP_0433 Streptococcus pneumoniae P1031 helicase, RecD/TraA family YP_002737641.1 385836 R 488223 CDS YP_002737642.1 225856131 7682471 complement(388330..388944) 1 NC_012467.1 identified by match to protein family HMM PF00717; match to protein family HMM TIGR02227; signal peptidase I 388944 lepB 7682471 lepB Streptococcus pneumoniae P1031 signal peptidase I YP_002737642.1 388330 R 488223 CDS YP_002737643.1 225856132 7681225 complement(388956..389828) 1 NC_012467.1 An endonuclease that specifically degrades the RNA strand of RNA-DNA hybrids; ribonuclease HIII 389828 rnhC 7681225 rnhC Streptococcus pneumoniae P1031 ribonuclease HIII YP_002737643.1 388956 R 488223 CDS YP_002737644.1 225856133 7682186 389993..390217 1 NC_012467.1 hypothetical protein 390217 7682186 SPP_0436 Streptococcus pneumoniae P1031 hypothetical protein YP_002737644.1 389993 D 488223 CDS YP_002737645.1 225856134 7680623 390214..390762 1 NC_012467.1 identified by match to protein family HMM PF02674; CvpA family protein 390762 cvpA 7680623 cvpA Streptococcus pneumoniae P1031 CvpA family protein YP_002737645.1 390214 D 488223 CDS YP_002737646.1 225856135 7681609 390866..393202 1 NC_012467.1 identified by match to protein family HMM PF00488; match to protein family HMM PF01713; match to protein family HMM TIGR01069; MutS2 family protein 393202 7681609 SPP_0438 Streptococcus pneumoniae P1031 MutS2 family protein YP_002737646.1 390866 D 488223 CDS YP_002737647.1 225856136 7682359 393545..394867 1 NC_012467.1 identified by match to protein family HMM PF01235; match to protein family HMM TIGR00835; D-alanine glycine permease 394867 7682359 SPP_0439 Streptococcus pneumoniae P1031 D-alanine glycine permease YP_002737647.1 393545 D 488223 CDS YP_002737648.1 225856137 7681350 395085..395633 1 NC_012467.1 identified by match to protein family HMM PF02627; match to protein family HMM TIGR00778; macrophage infectivity potentiator protein 395633 7681350 SPP_0440 Streptococcus pneumoniae P1031 macrophage infectivity potentiator protein YP_002737648.1 395085 D 488223 CDS YP_002737649.1 225856138 7682096 395743..396642 1 NC_012467.1 identified by match to protein family HMM PF03595; exfoliative toxin A 396642 7682096 SPP_0441 Streptococcus pneumoniae P1031 exfoliative toxin A YP_002737649.1 395743 D 488223 CDS YP_002737650.1 225856139 7682652 complement(396667..397941) 1 NC_012467.1 catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; seryl-tRNA synthetase 397941 serS 7682652 serS Streptococcus pneumoniae P1031 seryl-tRNA synthetase YP_002737650.1 396667 R 488223 CDS YP_002737651.1 225856140 7682249 complement(398155..398526) 1 NC_012467.1 identified by match to protein family HMM PF06115; ManO 398526 7682249 SPP_0443 Streptococcus pneumoniae P1031 ManO YP_002737651.1 398155 R 488223 CDS YP_002737652.1 225856141 7682212 complement(398529..399893) 1 NC_012467.1 catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP; lysine and threonine sensitive; aspartate kinase 399893 7682212 SPP_0444 Streptococcus pneumoniae P1031 aspartate kinase YP_002737652.1 398529 R 488223 CDS YP_002737653.1 225856142 7681043 complement(400071..400226) 1 NC_012467.1 hypothetical protein 400226 7681043 SPP_0445 Streptococcus pneumoniae P1031 hypothetical protein YP_002737653.1 400071 R 488223 CDS YP_002737654.1 225856143 7681112 400218..401003 1 NC_012467.1 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; enoyl-CoA hydratase 401003 7681112 SPP_0446 Streptococcus pneumoniae P1031 enoyl-CoA hydratase YP_002737654.1 400218 D 488223 CDS YP_002737655.1 225856144 7681083 401097..401531 1 NC_012467.1 identified by match to protein family HMM PF01047; match to protein family HMM PF03965; transcriptional regulator 401531 7681083 SPP_0447 Streptococcus pneumoniae P1031 transcriptional regulator YP_002737655.1 401097 D 488223 CDS YP_002737656.1 225856145 7681773 401531..402505 1 NC_012467.1 FabH; beta-ketoacyl-acyl carrier protein synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs; 3-oxoacyl-(acyl carrier protein) synthase III 402505 7681773 SPP_0448 Streptococcus pneumoniae P1031 3-oxoacyl-(acyl carrier protein) synthase III YP_002737656.1 401531 D 488223 CDS YP_002737657.1 225856146 7681979 402565..402789 1 NC_012467.1 carries the fatty acid chain in fatty acid biosynthesis; acyl carrier protein 402789 acpP 7681979 acpP Streptococcus pneumoniae P1031 acyl carrier protein YP_002737657.1 402565 D 488223 CDS YP_002737658.1 225856147 7682838 402908..403882 1 NC_012467.1 identified by match to protein family HMM PF03060; match to protein family HMM TIGR03151; enoyl-ACP reductase II 403882 7682838 SPP_0450 Streptococcus pneumoniae P1031 enoyl-ACP reductase II YP_002737658.1 402908 D 488223 CDS YP_002737659.1 225856148 7682129 403875..404795 1 NC_012467.1 identified by match to protein family HMM PF00698; match to protein family HMM TIGR00128; malonyl CoA-acyl carrier protein transacylase 404795 fabD 7682129 fabD Streptococcus pneumoniae P1031 malonyl CoA-acyl carrier protein transacylase YP_002737659.1 403875 D 488223 CDS YP_002737660.1 225856149 7682540 404829..405560 1 NC_012467.1 catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis; 3-ketoacyl-ACP reductase 405560 fabG 7682540 fabG Streptococcus pneumoniae P1031 3-ketoacyl-ACP reductase YP_002737660.1 404829 D 488223 CDS YP_002737661.1 225856150 7681007 405582..406817 1 NC_012467.1 FabF; beta-ketoacyl-ACP synthase II, KASII; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP; 3-oxoacyl-(acyl carrier protein) synthase II 406817 fabF 7681007 fabF Streptococcus pneumoniae P1031 3-oxoacyl-(acyl carrier protein) synthase II YP_002737661.1 405582 D 488223 CDS YP_002737662.1 225856151 7682019 406820..407305 1 NC_012467.1 composes the biotin carboxyl carrier protein subunit of the acetyl-CoA carboxylase complex, the enzyme that catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, which in turn controls the rate of fatty acid metabolism; acetyl-CoA carboxylase biotin carboxyl carrier protein subunit 407305 accB 7682019 accB Streptococcus pneumoniae P1031 acetyl-CoA carboxylase biotin carboxyl carrier protein subunit YP_002737662.1 406820 D 488223 CDS YP_002737663.1 225856152 7682029 407302..407724 1 NC_012467.1 in Pseudomonas aeruginosa this enzyme is a trimer of dimers; essential for membrane formation; performs third step of type II fatty acid biosynthesis; catalyzes dehydration of (3R)-hydroxyacyl-ACP to trans-2-acyl-ACP; (3R)-hydroxymyristoyl-ACP dehydratase 407724 fabZ 7682029 fabZ Streptococcus pneumoniae P1031 (3R)-hydroxymyristoyl-ACP dehydratase YP_002737663.1 407302 D 488223 CDS YP_002737664.1 225856153 7681183 407736..409103 1 NC_012467.1 an AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism; acetyl-CoA carboxylase biotin carboxylase subunit 409103 accC 7681183 accC Streptococcus pneumoniae P1031 acetyl-CoA carboxylase biotin carboxylase subunit YP_002737664.1 407736 D 488223 CDS YP_002737665.1 225856154 7681545 409140..410006 1 NC_012467.1 catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer of AccA2D2 subunits; acetyl-CoA carboxylase subunit beta 410006 accD 7681545 accD Streptococcus pneumoniae P1031 acetyl-CoA carboxylase subunit beta YP_002737665.1 409140 D 488223 CDS YP_002737666.1 225856155 7680863 410003..410770 1 NC_012467.1 catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer composed of two alpha (AccA) and two beta (AccD) subunits; one of the two catalytic subunits that can form the acetyl CoA carboxylase enzyme together with a carrier protein; these proteins present a shorter N-terminus; acetyl-CoA carboxylase subunit alpha 410770 accA 7680863 accA Streptococcus pneumoniae P1031 acetyl-CoA carboxylase subunit alpha YP_002737666.1 410003 D 488223 CDS YP_002737667.1 225856156 7682267 410929..411114 1 NC_012467.1 hypothetical protein 411114 7682267 SPP_0459 Streptococcus pneumoniae P1031 hypothetical protein YP_002737667.1 410929 D 488223 CDS YP_002737668.1 225856157 7680683 411171..411605 1 NC_012467.1 hypothetical protein 411605 7680683 SPP_0460 Streptococcus pneumoniae P1031 hypothetical protein YP_002737668.1 411171 D 488223 CDS YP_002737669.1 225856158 7680703 complement(411756..411890) 1 NC_012467.1 identified by glimmer; putative; hypothetical protein 411890 7680703 SPP_0461 Streptococcus pneumoniae P1031 hypothetical protein YP_002737669.1 411756 R 488223 CDS YP_002737670.1 225856159 7681199 complement(411904..412326) 1 NC_012467.1 Regulates rRNA biosynthesis by transcriptional antitermination; transcription antitermination protein NusB 412326 nusB 7681199 nusB Streptococcus pneumoniae P1031 transcription antitermination protein NusB YP_002737670.1 411904 R 488223 CDS YP_002737671.1 225856160 7682547 complement(412319..412708) 1 NC_012467.1 identified by match to protein family HMM PF03780; general stress protein, Gls24 family 412708 7682547 SPP_0463 Streptococcus pneumoniae P1031 general stress protein, Gls24 family YP_002737671.1 412319 R 488223 CDS YP_002737672.1 225856161 7681485 complement(412730..413290) 1 NC_012467.1 Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA; elongation factor P 413290 efp 7681485 efp Streptococcus pneumoniae P1031 elongation factor P YP_002737672.1 412730 R 488223 CDS YP_002737673.1 225856162 7682477 413458..413643 1 NC_012467.1 chlorohydrolase 413643 7682477 SPP_0465 Streptococcus pneumoniae P1031 chlorohydrolase YP_002737673.1 413458 D 488223 CDS YP_002737674.1 225856163 7681527 complement(413668..414711) 1 NC_012467.1 identified by match to protein family HMM PF00107; match to protein family HMM PF08240; L-iditol 2-dehydrogenase 414711 7681527 SPP_0466 Streptococcus pneumoniae P1031 L-iditol 2-dehydrogenase YP_002737674.1 413668 R 488223 CDS YP_002737675.1 225856164 7681361 complement(414835..416277) 1 NC_012467.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; aspartyl/glutamyl-tRNA amidotransferase subunit B 416277 gatB 7681361 gatB Streptococcus pneumoniae P1031 aspartyl/glutamyl-tRNA amidotransferase subunit B YP_002737675.1 414835 R 488223 CDS YP_002737676.1 225856165 7681619 complement(416277..417743) 1 NC_012467.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; aspartyl/glutamyl-tRNA amidotransferase subunit A 417743 gatA 7681619 gatA Streptococcus pneumoniae P1031 aspartyl/glutamyl-tRNA amidotransferase subunit A YP_002737676.1 416277 R 488223 CDS YP_002737677.1 225856166 7682430 complement(417743..418045) 1 NC_012467.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; some Mycoplasma proteins contain an N-terminal fusion to an unknown domain; aspartyl/glutamyl-tRNA amidotransferase subunit C 418045 gatC 7682430 gatC Streptococcus pneumoniae P1031 aspartyl/glutamyl-tRNA amidotransferase subunit C YP_002737677.1 417743 R 488223 CDS YP_002737678.1 225856167 7681071 418258..419802 1 NC_012467.1 stimulates the release of release factors 1 and 2 from the ribosome after hydrolysis of the ester bond in peptidyl-tRNA has occurred; GDP/GTP-binding protein; peptide chain release factor 3 419802 prfC 7681071 prfC Streptococcus pneumoniae P1031 peptide chain release factor 3 YP_002737678.1 418258 D 488223 CDS YP_002737679.1 225856168 7681257 420071..420556 1 NC_012467.1 identified by match to protein family HMM PF01501; glycosyl transferase, family 8 420556 7681257 SPP_0471 Streptococcus pneumoniae P1031 glycosyl transferase, family 8 YP_002737679.1 420071 D 488223 CDS YP_002737680.1 225856169 7682369 420672..420860 1 NC_012467.1 required for 70S ribosome assembly; 50S ribosomal protein L28 420860 rpmB 7682369 rpmB Streptococcus pneumoniae P1031 50S ribosomal protein L28 YP_002737680.1 420672 D 488223 CDS YP_002737681.1 225856170 7682791 421017..421382 1 NC_012467.1 identified by match to protein family HMM PF03780; alkaline shock protein 421382 7682791 SPP_0473 Streptococcus pneumoniae P1031 alkaline shock protein YP_002737681.1 421017 D 488223 CDS YP_002737682.1 225856171 7682630 421385..423052 1 NC_012467.1 identified by match to protein family HMM PF02734; dihydroxyacetone kinase family protein 423052 7682630 SPP_0474 Streptococcus pneumoniae P1031 dihydroxyacetone kinase family protein YP_002737682.1 421385 D 488223 CDS YP_002737683.1 225856172 7681961 423253..424953 1 NC_012467.1 catalyzes the formation of 2-acetolactate from pyruvate; also known as acetolactate synthase large subunit; acetolactate synthase catalytic subunit 424953 ilvB 7681961 ilvB Streptococcus pneumoniae P1031 acetolactate synthase catalytic subunit YP_002737683.1 423253 D 488223 CDS YP_002737684.1 225856173 7681474 424946..425422 1 NC_012467.1 with IlvI catalyzes the formation of 2-acetolactate from pyruvate, the small subunit is required for full activity and valine sensitivity; E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates, valine sensitivity and affinity for cofactors; also known as acetolactate synthase 3 small subunit; acetolactate synthase 3 regulatory subunit 425422 ilvH 7681474 ilvH Streptococcus pneumoniae P1031 acetolactate synthase 3 regulatory subunit YP_002737684.1 424946 D 488223 CDS YP_002737685.1 225856174 7680955 425488..426510 1 NC_012467.1 catalyzes the formation of (R)-2,3-dihydroxy-3-methylbutanoate from (S)-2-hydroxy-2-methyl-3-oxobutanoate in valine and isoleucine biosynthesis; ketol-acid reductoisomerase 426510 ilvC 7680955 ilvC Streptococcus pneumoniae P1031 ketol-acid reductoisomerase YP_002737685.1 425488 D 488223 CDS YP_002737686.1 225856175 7682694 426617..426853 1 NC_012467.1 hypothetical protein 426853 7682694 SPP_0478 Streptococcus pneumoniae P1031 hypothetical protein YP_002737686.1 426617 D 488223 CDS YP_002737687.1 225856176 7681558 427091..427447 1 NC_012467.1 hypothetical protein 427447 7681558 SPP_0479 Streptococcus pneumoniae P1031 hypothetical protein YP_002737687.1 427091 D 488223 CDS YP_002737688.1 225856177 7682320 427497..428747 1 NC_012467.1 catalyzes the formation of 2-oxobutanoate from L-threonine; biosynthetic; threonine dehydratase 428747 ilvA 7682320 ilvA Streptococcus pneumoniae P1031 threonine dehydratase YP_002737688.1 427497 D 488223 CDS YP_002737689.1 225856178 7682319 428889..429077 1 NC_012467.1 hypothetical protein 429077 7682319 SPP_0481 Streptococcus pneumoniae P1031 hypothetical protein YP_002737689.1 428889 D 488223 CDS YP_002737690.1 225856179 7682616 429618..429833 1 NC_012467.1 hypothetical protein 429833 7682616 SPP_0482 Streptococcus pneumoniae P1031 hypothetical protein YP_002737690.1 429618 D 488223 CDS YP_002737691.1 225856180 7682116 complement(429942..430682) 1 NC_012467.1 identified by match to protein family HMM PF00005; glutamate/aspartate ABC transporter, ATP-binding protein 430682 gltL 7682116 gltL Streptococcus pneumoniae P1031 glutamate/aspartate ABC transporter, ATP-binding protein YP_002737691.1 429942 R 488223 CDS YP_002737692.1 225856181 7682505 complement(430682..432247) 1 NC_012467.1 identified by match to protein family HMM PF00497; match to protein family HMM PF00528; match to protein family HMM TIGR01726; amino acid ABC transporter permease/substrate-binding protein 432247 7682505 SPP_0484 Streptococcus pneumoniae P1031 amino acid ABC transporter permease/substrate-binding protein YP_002737692.1 430682 R 488223 CDS YP_002737693.1 225856182 7681717 432385..434274 1 NC_012467.1 hypothetical protein 434274 7681717 SPP_0486 Streptococcus pneumoniae P1031 hypothetical protein YP_002737693.1 432385 D 488223 CDS YP_002737694.1 225856183 7681797 complement(434271..434441) 1 NC_012467.1 hypothetical protein 434441 7681797 SPP_0485 Streptococcus pneumoniae P1031 hypothetical protein YP_002737694.1 434271 R 488223 CDS YP_002737695.1 225856184 7681196 complement(434575..435123) 1 NC_012467.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by match to protein family HMM PF02371; transposase 435123 7681196 SPP_0487 Streptococcus pneumoniae P1031 transposase YP_002737695.1 434575 R 488223 CDS YP_002737696.1 225856185 7681321 complement(435321..435443) 1 NC_012467.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; transposase 435443 7681321 SPP_0488 Streptococcus pneumoniae P1031 transposase YP_002737696.1 435321 R 488223 CDS YP_002737697.1 225856186 7682252 435699..436544 1 NC_012467.1 BacA; phosphatase activity in Escherichia coli not kinase; involved in bacitracin resistance as bacitracin supposedly sequesters undecaprenyl disphosphate which reduces the pool of lipid carrier available to the cell; UDP pyrophosphate phosphatase 436544 7682252 SPP_0489 Streptococcus pneumoniae P1031 UDP pyrophosphate phosphatase YP_002737697.1 435699 D 488223 CDS YP_002737698.1 225856187 7682523 436537..436665 1 NC_012467.1 hypothetical protein 436665 7682523 SPP_0490 Streptococcus pneumoniae P1031 hypothetical protein YP_002737698.1 436537 D 488223 CDS YP_002737699.1 225856188 7681186 complement(436691..437752) 1 NC_012467.1 involved in translesion DNA polymerization with beta clamp of polymerase III; belongs to Y family of polymerases; does not contain proofreading function; DNA polymerase IV 437752 7681186 SPP_0491 Streptococcus pneumoniae P1031 DNA polymerase IV YP_002737699.1 436691 R 488223 CDS YP_002737700.1 225856189 7682043 complement(437797..437919) 1 NC_012467.1 identified by glimmer; putative; hypothetical protein 437919 7682043 SPP_0492 Streptococcus pneumoniae P1031 hypothetical protein YP_002737700.1 437797 R 488223 CDS YP_002737701.1 225856190 7681013 438147..440471 1 NC_012467.1 identified by match to protein family HMM PF01228; match to protein family HMM PF02901; match to protein family HMM TIGR01255; formate acetyltransferase 440471 pflB 7681013 pflB Streptococcus pneumoniae P1031 formate acetyltransferase YP_002737701.1 438147 D 488223 CDS YP_002737702.1 225856191 7681756 complement(440843..441061) 1 NC_012467.1 hypothetical protein 441061 7681756 SPP_0494 Streptococcus pneumoniae P1031 hypothetical protein YP_002737702.1 440843 R 488223 CDS YP_002737703.1 225856192 7681924 complement(441388..441672) 1 NC_012467.1 hypothetical protein 441672 7681924 SPP_0495 Streptococcus pneumoniae P1031 hypothetical protein YP_002737703.1 441388 R 488223 CDS YP_002737704.1 225856193 7681399 442064..442237 1 NC_012467.1 identified by glimmer; putative; hypothetical protein 442237 7681399 SPP_0496 Streptococcus pneumoniae P1031 hypothetical protein YP_002737704.1 442064 D 488223 CDS YP_002737705.1 225856194 7680961 complement(442876..442989) 1 NC_012467.1 identified by glimmer; putative; hypothetical protein 442989 7680961 SPP_0497 Streptococcus pneumoniae P1031 hypothetical protein YP_002737705.1 442876 R 488223 CDS YP_002737706.1 225856195 7681479 complement(443277..444500) 1 NC_012467.1 identified by match to protein family HMM PF00480; ROK family protein 444500 7681479 SPP_0498 Streptococcus pneumoniae P1031 ROK family protein YP_002737706.1 443277 R 488223 CDS YP_002737707.1 225856196 7680819 444668..445990 1 NC_012467.1 identified by match to protein family HMM PF02378; match to protein family HMM TIGR00410; lichenan permease iic component (pts system lichenan-specific eiiccomponent) (eiic-lic) 445990 7680819 SPP_0499 Streptococcus pneumoniae P1031 lichenan permease iic component (pts system lichenan-specific eiiccomponent) (eiic-lic) YP_002737707.1 444668 D 488223 CDS YP_002737708.1 225856197 7680872 445992..447878 1 NC_012467.1 hypothetical protein 447878 7680872 SPP_0500 Streptococcus pneumoniae P1031 hypothetical protein YP_002737708.1 445992 D 488223 CDS YP_002737709.1 225856198 7682525 448046..448390 1 NC_012467.1 identified by match to protein family HMM PF02255; lactose-specific phosphotransferase enzyme iia component (pts system lactose-specific eiia component) (eiia-lac) (eiii-lac) 448390 7682525 SPP_0501 Streptococcus pneumoniae P1031 lactose-specific phosphotransferase enzyme iia component (pts system lactose-specific eiia component) (eiia-lac) (eiii-lac) YP_002737709.1 448046 D 488223 CDS YP_002737710.1 225856199 7682301 448400..449812 1 NC_012467.1 catalyzes the formation of 6-phospho-galactose from a 6-phospho-beta-galactoside; 6-phospho-beta-galactosidase 449812 lacG1 7682301 lacG1 Streptococcus pneumoniae P1031 6-phospho-beta-galactosidase YP_002737710.1 448400 D 488223 CDS YP_002737711.1 225856200 7682014 449882..451561 1 NC_012467.1 identified by match to protein family HMM PF02302; match to protein family HMM PF02378; pts system lactose-specific eiicb component (eiicb-lac) (eii-lac) 451561 7682014 SPP_0503 Streptococcus pneumoniae P1031 pts system lactose-specific eiicb component (eiicb-lac) (eii-lac) YP_002737711.1 449882 D 488223 CDS YP_002737712.1 225856201 7681201 complement(451687..453126) 1 NC_012467.1 identified by match to protein family HMM PF02386; potassium uptake protein, Trk family 453126 7681201 SPP_0504 Streptococcus pneumoniae P1031 potassium uptake protein, Trk family YP_002737712.1 451687 R 488223 CDS YP_002737713.1 225856202 7681470 complement(453130..454479) 1 NC_012467.1 involved in potassium uptake; found to be peripherally associated with the inner membrane in Escherichia coli; contains an NAD-binding domain; potassium transporter peripheral membrane component 454479 trkA 7681470 trkA Streptococcus pneumoniae P1031 potassium transporter peripheral membrane component YP_002737713.1 453130 R 488223 CDS YP_002737714.1 225856203 7681151 454667..455515 1 NC_012467.1 identified by match to protein family HMM PF01887; hypothetical protein 455515 7681151 SPP_0506 Streptococcus pneumoniae P1031 hypothetical protein YP_002737714.1 454667 D 488223 CDS YP_002737715.1 225856204 7682113 455530..456078 1 NC_012467.1 identified by match to protein family HMM PF07155; hypothetical protein 456078 7682113 SPP_0507 Streptococcus pneumoniae P1031 hypothetical protein YP_002737715.1 455530 D 488223 CDS YP_002737716.1 225856205 7681392 456085..456342 1 NC_012467.1 hypothetical protein 456342 7681392 SPP_0508 Streptococcus pneumoniae P1031 hypothetical protein YP_002737716.1 456085 D 488223 CDS YP_002737717.1 225856206 7681939 456444..458126 1 NC_012467.1 identified by match to protein family HMM PF00005; putative ABC transporter ATP-binding protein 458126 7681939 SPP_0509 Streptococcus pneumoniae P1031 putative ABC transporter ATP-binding protein YP_002737717.1 456444 D 488223 CDS YP_002737718.1 225856207 7681586 458111..458941 1 NC_012467.1 identified by match to protein family HMM PF02361; cobalt transport family protein 458941 7681586 SPP_0510 Streptococcus pneumoniae P1031 cobalt transport family protein YP_002737718.1 458111 D 488223 CDS YP_002737719.1 225856208 7680638 459134..459637 1 NC_012467.1 identified by match to protein family HMM PF00588; CspR 459637 cspR 7680638 cspR Streptococcus pneumoniae P1031 CspR YP_002737719.1 459134 D 488223 CDS YP_002737720.1 225856209 7681258 460090..460653 1 NC_012467.1 hypothetical protein 460653 7681258 SPP_0512 Streptococcus pneumoniae P1031 hypothetical protein YP_002737720.1 460090 D 488223 CDS YP_002737721.1 225856210 7681267 460667..461293 1 NC_012467.1 identified by match to protein family HMM PF01569; PAP2 family protein 461293 7681267 SPP_0513 Streptococcus pneumoniae P1031 PAP2 family protein YP_002737721.1 460667 D 488223 CDS YP_002737722.1 225856211 7681976 461321..461710 1 NC_012467.1 hypothetical protein 461710 7681976 SPP_0514 Streptococcus pneumoniae P1031 hypothetical protein YP_002737722.1 461321 D 488223 CDS YP_002737723.1 225856212 7681999 461715..462164 1 NC_012467.1 hypothetical protein 462164 7681999 SPP_0515 Streptococcus pneumoniae P1031 hypothetical protein YP_002737723.1 461715 D 488223 CDS YP_002737724.1 225856213 7682818 462292..462879 1 NC_012467.1 participates in both the initiation and recycling phases of transcription; in the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling; DNA-directed RNA polymerase subunit delta 462879 rpoE 7682818 rpoE Streptococcus pneumoniae P1031 DNA-directed RNA polymerase subunit delta YP_002737724.1 462292 D 488223 CDS YP_002737725.1 225856214 7680799 463015..463140 1 NC_012467.1 identified by glimmer; putative; hypothetical protein 463140 7680799 SPP_0517 Streptococcus pneumoniae P1031 hypothetical protein YP_002737725.1 463015 D 488223 CDS YP_002737726.1 225856215 7682380 463269..464876 1 NC_012467.1 CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer; CTP synthetase 464876 pyrG 7682380 pyrG Streptococcus pneumoniae P1031 CTP synthetase YP_002737726.1 463269 D 488223 CDS YP_002737727.1 225856216 7681772 complement(465435..467066) 1 NC_012467.1 identified by match to protein family HMM PF01895; match to protein family HMM PF02690; match to protein family HMM TIGR00704; sodium-dependent phosphate transporter 467066 7681772 SPP_0519 Streptococcus pneumoniae P1031 sodium-dependent phosphate transporter YP_002737727.1 465435 R 488223 CDS YP_002737728.1 225856217 7681109 467431..472299 1 NC_012467.1 identified by match to protein family HMM PF00746; match to protein family HMM PF00754; match to protein family HMM PF03644; match to protein family HMM PF07501; match to protein family HMM PF07523; match to protein family HMM PF07554; match to protein family HMM TIGR01167; endo-beta-N-acetylglucosaminidase D 472299 7681109 SPP_0520 Streptococcus pneumoniae P1031 endo-beta-N-acetylglucosaminidase D YP_002737728.1 467431 D 488223 CDS YP_002737729.1 225856218 7682040 472389..473585 1 NC_012467.1 Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway; phosphoglycerate kinase 473585 pgk 7682040 pgk Streptococcus pneumoniae P1031 phosphoglycerate kinase YP_002737729.1 472389 D 488223 CDS YP_002737730.1 225856219 7682188 473721..474248 1 NC_012467.1 hypothetical protein 474248 7682188 SPP_0522 Streptococcus pneumoniae P1031 hypothetical protein YP_002737730.1 473721 D 488223 CDS YP_002737731.1 225856220 7681141 474325..474681 1 NC_012467.1 identified by match to protein family HMM PF00376; HTH-type transcriptional regulator GlnR 474681 7681141 SPP_0523 Streptococcus pneumoniae P1031 HTH-type transcriptional regulator GlnR YP_002737731.1 474325 D 488223 CDS YP_002737732.1 225856221 7682623 474718..476064 1 NC_012467.1 identified by match to protein family HMM PF00120; match to protein family HMM PF03951; match to protein family HMM TIGR00653; glutamine synthetase, type I 476064 glnA 7682623 glnA Streptococcus pneumoniae P1031 glutamine synthetase, type I YP_002737732.1 474718 D 488223 CDS YP_002737733.1 225856222 7682870 complement(476507..477853) 1 NC_012467.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop; identified by match to protein family HMM PF01609; Spn1 transposase 477853 7682870 SPP_0525 Streptococcus pneumoniae P1031 Spn1 transposase YP_002737733.1 476507 R 488223 CDS YP_002737734.1 225856223 7682208 478239..478376 1 NC_012467.1 hypothetical protein 478376 7682208 SPP_0526 Streptococcus pneumoniae P1031 hypothetical protein YP_002737734.1 478239 D 488223 CDS YP_002737735.1 225856224 7682573 478547..479827 1 NC_012467.1 identified by match to protein family HMM PF01420; type I site-specific deoxyribonuclease chain S 479827 7682573 SPP_0527 Streptococcus pneumoniae P1031 type I site-specific deoxyribonuclease chain S YP_002737735.1 478547 D 488223 CDS YP_002737736.1 225856225 7682284 479884..480681 1 NC_012467.1 identified by match to protein family HMM PF00589; integrase/recombinase, phage integrase family 480681 7682284 SPP_0528 Streptococcus pneumoniae P1031 integrase/recombinase, phage integrase family YP_002737736.1 479884 D 488223 CDS YP_002737737.1 225856226 7682531 480692..481297 1 NC_012467.1 type I restriction-modification system, S subunit, putative 481297 7682531 SPP_0530 Streptococcus pneumoniae P1031 type I restriction-modification system, S subunit, putative YP_002737737.1 480692 D 488223 CDS YP_002737738.1 225856227 7681018 complement(481245..482795) 1 NC_012467.1 identified by match to protein family HMM PF01420; type I restriction enzyme 482795 7681018 SPP_0529 Streptococcus pneumoniae P1031 type I restriction enzyme YP_002737738.1 481245 R 488223 CDS YP_002737739.1 225856228 7681215 complement(482795..484258) 1 NC_012467.1 identified by match to protein family HMM PF02384; match to protein family HMM PF05175; type I restriction enzyme 484258 7681215 SPP_0531 Streptococcus pneumoniae P1031 type I restriction enzyme YP_002737739.1 482795 R 488223 CDS YP_002737740.1 225856229 7681405 complement(486955..487083) 1 NC_012467.1 hypothetical protein 487083 7681405 SPP_0534 Streptococcus pneumoniae P1031 hypothetical protein YP_002737740.1 486955 R 488223 CDS YP_002737741.1 225856230 7682445 487212..487721 1 NC_012467.1 hypothetical protein 487721 7682445 SPP_0535 Streptococcus pneumoniae P1031 hypothetical protein YP_002737741.1 487212 D 488223 CDS YP_002737742.1 225856231 7682288 487885..488919 1 NC_012467.1 Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons; heat-inducible transcription repressor 488919 hrcA 7682288 hrcA Streptococcus pneumoniae P1031 heat-inducible transcription repressor YP_002737742.1 487885 D 488223 CDS YP_002737743.1 225856232 7681758 488946..489470 1 NC_012467.1 with DnaK and DnaJ acts in response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins; may act as a thermosensor; heat shock protein GrpE 489470 grpE 7681758 grpE Streptococcus pneumoniae P1031 heat shock protein GrpE YP_002737743.1 488946 D 488223 CDS YP_002737744.1 225856233 7681541 489950..491773 1 NC_012467.1 heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria; molecular chaperone DnaK 491773 dnaK 7681541 dnaK Streptococcus pneumoniae P1031 molecular chaperone DnaK YP_002737744.1 489950 D 488223 CDS YP_002737745.1 225856234 7681743 491786..492139 1 NC_012467.1 identified by glimmer; putative; hypothetical protein 492139 7681743 SPP_0539 Streptococcus pneumoniae P1031 hypothetical protein YP_002737745.1 491786 D 488223 CDS YP_002737746.1 225856235 7681727 492344..493480 1 NC_012467.1 chaperone Hsp40; co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion; chaperone protein DnaJ 493480 dnaJ 7681727 dnaJ Streptococcus pneumoniae P1031 chaperone protein DnaJ YP_002737746.1 492344 D 488223 CDS YP_002737747.1 225856236 7682816 complement(493802..494176) 1 NC_012467.1 chlorohydrolase 494176 7682816 SPP_0541 Streptococcus pneumoniae P1031 chlorohydrolase YP_002737747.1 493802 R 488223 CDS YP_002737748.1 225856237 7681837 complement(494338..494625) 1 NC_012467.1 hypothetical protein 494625 7681837 SPP_0542 Streptococcus pneumoniae P1031 hypothetical protein YP_002737748.1 494338 R 488223 CDS YP_002737749.1 225856238 7681031 complement(494635..495045) 1 NC_012467.1 identified by match to protein family HMM PF01230; histidine triad domain protein 495045 7681031 SPP_0543 Streptococcus pneumoniae P1031 histidine triad domain protein YP_002737749.1 494635 R 488223 CDS YP_002737750.1 225856239 7681354 495113..495844 1 NC_012467.1 identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 495844 7681354 SPP_0544 Streptococcus pneumoniae P1031 ABC transporter ATP-binding protein YP_002737750.1 495113 D 488223 CDS YP_002737751.1 225856240 7682378 495841..496890 1 NC_012467.1 identified by match to protein family HMM PF05975; ABC transporter permease 496890 7682378 SPP_0545 Streptococcus pneumoniae P1031 ABC transporter permease YP_002737751.1 495841 D 488223 CDS YP_002737752.1 225856241 7682670 complement(497058..497387) 1 NC_012467.1 BlpT protein, fusion 497387 7682670 SPP_0546 Streptococcus pneumoniae P1031 BlpT protein, fusion YP_002737752.1 497058 R 488223 CDS YP_002737753.1 225856242 7682534 497664..498002 1 NC_012467.1 identified by match to protein family HMM PF04397; regulatory protein 498002 7682534 SPP_0547 Streptococcus pneumoniae P1031 regulatory protein YP_002737753.1 497664 D 488223 CDS YP_002737754.1 225856243 7681437 498007..498744 1 NC_012467.1 identified by match to protein family HMM PF00072; match to protein family HMM PF04397; response regulator 498744 7681437 SPP_0548 Streptococcus pneumoniae P1031 response regulator YP_002737754.1 498007 D 488223 CDS YP_002737755.1 225856244 7681332 498758..500098 1 NC_012467.1 histidine kinase 500098 7681332 SPP_0549 Streptococcus pneumoniae P1031 histidine kinase YP_002737755.1 498758 D 488223 CDS YP_002737756.1 225856245 7681815 complement(500142..500297) 1 NC_012467.1 identified by match to protein family HMM PF08128; match to protein family HMM TIGR01847; double glycine cleavage site bacteriolysin superfamily 500297 7681815 SPP_0550 Streptococcus pneumoniae P1031 double glycine cleavage site bacteriolysin superfamily YP_002737756.1 500142 R 488223 CDS YP_002737757.1 225856246 7682384 complement(500354..501715) 1 NC_012467.1 identified by match to protein family HMM TIGR01000; BlpC ABC transporter 501715 7682384 SPP_0551 Streptococcus pneumoniae P1031 BlpC ABC transporter YP_002737757.1 500354 R 488223 CDS YP_002737758.1 225856247 7681988 complement(501726..503879) 1 NC_012467.1 identified by match to protein family HMM PF00005; match to protein family HMM PF00664; match to protein family HMM PF03412; match to protein family HMM TIGR01193; transport/processing ATP-binding protein ComA 503879 7681988 SPP_0552 Streptococcus pneumoniae P1031 transport/processing ATP-binding protein ComA YP_002737758.1 501726 R 488223 CDS YP_002737759.1 225856248 7682558 504161..504415 1 NC_012467.1 identified by match to protein family HMM TIGR01847; BlpM 504415 7682558 SPP_0553 Streptococcus pneumoniae P1031 BlpM YP_002737759.1 504161 D 488223 CDS YP_002737760.1 225856249 7682258 504431..504634 1 NC_012467.1 hypothetical protein 504634 7682258 SPP_0554 Streptococcus pneumoniae P1031 hypothetical protein YP_002737760.1 504431 D 488223 CDS YP_002737761.1 225856250 7680679 504878..505027 1 NC_012467.1 identified by match to protein family HMM TIGR01847; hypothetical protein 505027 7680679 SPP_0555 Streptococcus pneumoniae P1031 hypothetical protein YP_002737761.1 504878 D 488223 CDS YP_002737762.1 225856251 7680835 505009..505128 1 NC_012467.1 hypothetical protein 505128 7680835 SPP_0556 Streptococcus pneumoniae P1031 hypothetical protein YP_002737762.1 505009 D 488223 CDS YP_002737763.1 225856252 7682316 505131..505250 1 NC_012467.1 hypothetical protein 505250 7682316 SPP_0557 Streptococcus pneumoniae P1031 hypothetical protein YP_002737763.1 505131 D 488223 CDS YP_002737764.1 225856253 7682308 505363..505479 1 NC_012467.1 hypothetical protein 505479 7682308 SPP_0558 Streptococcus pneumoniae P1031 hypothetical protein YP_002737764.1 505363 D 488223 CDS YP_002737765.1 225856254 7681951 505547..505708 1 NC_012467.1 hypothetical protein 505708 7681951 SPP_0559 Streptococcus pneumoniae P1031 hypothetical protein YP_002737765.1 505547 D 488223 CDS YP_002737766.1 225856255 7681674 506267..506446 1 NC_012467.1 hypothetical protein 506446 7681674 SPP_0561 Streptococcus pneumoniae P1031 hypothetical protein YP_002737766.1 506267 D 488223 CDS YP_002737767.1 225856256 7681728 506478..506618 1 NC_012467.1 immunity protein BlpL 506618 7681728 SPP_0562 Streptococcus pneumoniae P1031 immunity protein BlpL YP_002737767.1 506478 D 488223 CDS YP_002737768.1 225856257 7682100 506718..507101 1 NC_012467.1 immunity protein BlpX 507101 7682100 SPP_0563 Streptococcus pneumoniae P1031 immunity protein BlpX YP_002737768.1 506718 D 488223 CDS YP_002737769.1 225856258 7681636 507153..507842 1 NC_012467.1 identified by match to protein family HMM PF02517; BlpY protein 507842 7681636 SPP_0564 Streptococcus pneumoniae P1031 BlpY protein YP_002737769.1 507153 D 488223 CDS YP_002737770.1 225856259 7681237 508268..508879 1 NC_012467.1 identified by match to protein family HMM PF02517; ABC transporter ATP-binding protein 508879 7681237 SPP_0566 Streptococcus pneumoniae P1031 ABC transporter ATP-binding protein YP_002737770.1 508268 D 488223 CDS YP_002737771.1 225856260 7681889 509040..509834 1 NC_012467.1 identified by match to protein family HMM PF01636; phosphotransferase enzyme family 509834 7681889 SPP_0567 Streptococcus pneumoniae P1031 phosphotransferase enzyme family YP_002737771.1 509040 D 488223 CDS YP_002737772.1 225856261 7680876 509831..510466 1 NC_012467.1 tRNA (guanine-N(7)-)-methyltransferase; catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA by transferring the methyl residue from S-adenosyl-L-methionine; tRNA (guanine-N(7)-)-methyltransferase 510466 trmB 7680876 trmB Streptococcus pneumoniae P1031 tRNA (guanine-N(7)-)-methyltransferase YP_002737772.1 509831 D 488223 CDS YP_002737773.1 225856262 7681139 510592..511071 1 NC_012467.1 in Streptococcus pneumoniae this gene was found to be essential; structure determination of the Streptococcus protein shows that it is similar to a number of other proteins; hypothetical protein 511071 7681139 SPP_0569 Streptococcus pneumoniae P1031 hypothetical protein YP_002737773.1 510592 D 488223 CDS YP_002737774.1 225856263 7680812 511115..512251 1 NC_012467.1 modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination; transcription elongation factor NusA 512251 nusA 7680812 nusA Streptococcus pneumoniae P1031 transcription elongation factor NusA YP_002737774.1 511115 D 488223 CDS YP_002737775.1 225856264 7680901 512273..512566 1 NC_012467.1 identified by match to protein family HMM PF04296; putative chain a, hypothetical cytosolic protein coded by gene from nusainfb, ylxr homologue 512566 7680901 SPP_0571 Streptococcus pneumoniae P1031 putative chain a, hypothetical cytosolic protein coded by gene from nusainfb, ylxr homologue YP_002737775.1 512273 D 488223 CDS YP_002737776.1 225856265 7680951 512559..512858 1 NC_012467.1 identified by match to protein family HMM PF01248; hypothetical protein 512858 7680951 SPP_0572 Streptococcus pneumoniae P1031 hypothetical protein YP_002737776.1 512559 D 488223 CDS YP_002737777.1 225856266 7681457 512875..515667 1 NC_012467.1 Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; translation initiation factor IF-2 515667 infB 7681457 infB Streptococcus pneumoniae P1031 translation initiation factor IF-2 YP_002737777.1 512875 D 488223 CDS YP_002737778.1 225856267 7681448 515918..516268 1 NC_012467.1 associates with free 30S ribosomal subunits; essential for efficient processing of 16S rRNA; in Escherichia coli rbfA is induced by cold shock; ribosome-binding factor A 516268 rbfA 7681448 rbfA Streptococcus pneumoniae P1031 ribosome-binding factor A YP_002737778.1 515918 D 488223 CDS YP_002737779.1 225856268 7682522 516547..517326 1 NC_012467.1 hypothetical protein 517326 7682522 SPP_0575 Streptococcus pneumoniae P1031 hypothetical protein YP_002737779.1 516547 D 488223 CDS YP_002737780.1 225856269 7682809 517328..517510 1 NC_012467.1 hypothetical protein 517510 7682809 SPP_0576 Streptococcus pneumoniae P1031 hypothetical protein YP_002737780.1 517328 D 488223 CDS YP_002737781.1 225856270 7680656 complement(517777..517929) 1 NC_012467.1 identified by glimmer; putative; hypothetical protein 517929 7680656 SPP_0577 Streptococcus pneumoniae P1031 hypothetical protein YP_002737781.1 517777 R 488223 CDS YP_002737782.1 225856271 7682644 517960..518193 1 NC_012467.1 identified by match to protein family HMM PF08984; hypothetical protein 518193 7682644 SPP_0578 Streptococcus pneumoniae P1031 hypothetical protein YP_002737782.1 517960 D 488223 CDS YP_002737783.1 225856272 7681611 518193..519527 1 NC_012467.1 identified by match to protein family HMM PF01814; match to protein family HMM PF04282; hemerythrin HHE cation binding domain subfamily, putative 519527 7681611 SPP_0579 Streptococcus pneumoniae P1031 hemerythrin HHE cation binding domain subfamily, putative YP_002737783.1 518193 D 488223 CDS YP_002737784.1 225856273 7680904 519537..519791 1 NC_012467.1 identified by match to protein family HMM PF08930; hypothetical protein 519791 7680904 SPP_0580 Streptococcus pneumoniae P1031 hypothetical protein YP_002737784.1 519537 D 488223 CDS YP_002737785.1 225856274 7682564 519887..520282 1 NC_012467.1 hypothetical protein 520282 7682564 SPP_0581 Streptococcus pneumoniae P1031 hypothetical protein YP_002737785.1 519887 D 488223 CDS YP_002737786.1 225856275 7681208 520695..521144 1 NC_012467.1 identified by glimmer; putative; hypothetical protein 521144 7681208 SPP_0582 Streptococcus pneumoniae P1031 hypothetical protein YP_002737786.1 520695 D 488223 CDS YP_002737787.1 225856276 7682578 521131..521691 1 NC_012467.1 identified by match to protein family HMM PF00583; acetyltransferase, gnat family 521691 7682578 SPP_0583 Streptococcus pneumoniae P1031 acetyltransferase, gnat family YP_002737787.1 521131 D 488223 CDS YP_002737788.1 225856277 7681713 521691..522269 1 NC_012467.1 shikimate kinase 522269 7681713 SPP_0584 Streptococcus pneumoniae P1031 shikimate kinase YP_002737788.1 521691 D 488223 CDS YP_002737789.1 225856278 7682127 522262..524913 1 NC_012467.1 valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain; valyl-tRNA synthetase 524913 valS 7682127 valS Streptococcus pneumoniae P1031 valyl-tRNA synthetase YP_002737789.1 522262 D 488223 CDS YP_002737790.1 225856279 7682453 524983..525738 1 NC_012467.1 hypothetical protein 525738 7682453 SPP_0586 Streptococcus pneumoniae P1031 hypothetical protein YP_002737790.1 524983 D 488223 CDS YP_002737791.1 225856280 7680943 526013..526816 1 NC_012467.1 identified by match to protein family HMM PF02661; Fic protein family 526816 7680943 SPP_0587 Streptococcus pneumoniae P1031 Fic protein family YP_002737791.1 526013 D 488223 CDS YP_002737792.1 225856281 7681833 complement(527482..528261) 1 NC_012467.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; transposase 528261 7681833 SPP_0589 Streptococcus pneumoniae P1031 transposase YP_002737792.1 527482 R 488223 CDS YP_002737793.1 225856282 7682475 531431..532270 1 NC_012467.1 identified by match to protein family HMM PF00874; match to protein family HMM PF03123; transcription antiterminator LicT 532270 7682475 SPP_0592 Streptococcus pneumoniae P1031 transcription antiterminator LicT YP_002737793.1 531431 D 488223 CDS YP_002737794.1 225856283 7681292 532288..534126 1 NC_012467.1 identified by match to protein family HMM PF00358; match to protein family HMM PF00367; match to protein family HMM PF02378; match to protein family HMM TIGR00830; match to protein family HMM TIGR01995; pts system beta-glucoside-specific eiibca component (eiibca-bgl) (eii-bgl) 534126 7681292 SPP_0593 Streptococcus pneumoniae P1031 pts system beta-glucoside-specific eiibca component (eiibca-bgl) (eii-bgl) YP_002737794.1 532288 D 488223 CDS YP_002737795.1 225856284 7680622 534139..535554 1 NC_012467.1 identified by match to protein family HMM PF00232; beta-glucosidase (Gentiobiase) (Cellobiase) (Beta-D-glucoside glucohydrolase) (Amygdalase) 535554 7680622 SPP_0594 Streptococcus pneumoniae P1031 beta-glucosidase (Gentiobiase) (Cellobiase) (Beta-D-glucoside glucohydrolase) (Amygdalase) YP_002737795.1 534139 D 488223 CDS YP_002737796.1 225856285 7681125 536104..537192 1 NC_012467.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily; phenylalanyl-tRNA synthetase subunit alpha 537192 pheS 7681125 pheS Streptococcus pneumoniae P1031 phenylalanyl-tRNA synthetase subunit alpha YP_002737796.1 536104 D 488223 CDS YP_002737797.1 225856286 7681530 537192..537701 1 NC_012467.1 identified by match to protein family HMM PF00583; acetyltransferase, gnat family 537701 7681530 SPP_0596 Streptococcus pneumoniae P1031 acetyltransferase, gnat family YP_002737797.1 537192 D 488223 CDS YP_002737798.1 225856287 7681390 537778..540180 1 NC_012467.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily; phenylalanyl-tRNA synthetase subunit beta 540180 pheT 7681390 pheT Streptococcus pneumoniae P1031 phenylalanyl-tRNA synthetase subunit beta YP_002737798.1 537778 D 488223 CDS YP_002737799.1 225856288 7682849 complement(540248..541249) 1 NC_012467.1 identified by match to protein family HMM PF03372; endonuclease/exonuclease/phosphatase family 541249 7682849 SPP_0598 Streptococcus pneumoniae P1031 endonuclease/exonuclease/phosphatase family YP_002737799.1 540248 R 488223 CDS YP_002737800.1 225856289 7682450 541978..542244 1 NC_012467.1 identified by match to protein family HMM PF01381; helix-turn-helix domain protein 542244 7682450 SPP_0601 Streptococcus pneumoniae P1031 helix-turn-helix domain protein YP_002737800.1 541978 D 488223 CDS YP_002737801.1 225856290 7681566 542504..544753 1 NC_012467.1 catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine to form methionine; 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase 544753 metE 7681566 metE Streptococcus pneumoniae P1031 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase YP_002737801.1 542504 D 488223 CDS YP_002737802.1 225856291 7682491 544817..545683 1 NC_012467.1 identified by match to protein family HMM PF02219; match to protein family HMM TIGR00676; 5,10-methylenetetrahydrofolate reductase 545683 metF 7682491 metF Streptococcus pneumoniae P1031 5,10-methylenetetrahydrofolate reductase YP_002737802.1 544817 D 488223 CDS YP_002737803.1 225856292 7681565 548471..549088 1 NC_012467.1 identified by match to protein family HMM TIGR01172; serine O-acetyltransferase 549088 cysE 7681565 cysE Streptococcus pneumoniae P1031 serine O-acetyltransferase YP_002737803.1 548471 D 488223 CDS YP_002737804.1 225856293 7681264 549100..549984 1 NC_012467.1 identified by match to protein family HMM PF00583; acetyltransferase, gnat family 549984 7681264 SPP_0607 Streptococcus pneumoniae P1031 acetyltransferase, gnat family YP_002737804.1 549100 D 488223 CDS YP_002737805.1 225856294 7681667 550066..551409 1 NC_012467.1 catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA; cysteinyl-tRNA synthetase 551409 cysS 7681667 cysS Streptococcus pneumoniae P1031 cysteinyl-tRNA synthetase YP_002737805.1 550066 D 488223 CDS YP_002737806.1 225856295 7681744 551402..551788 1 NC_012467.1 identified by match to protein family HMM PF00636; ribonuclease III family protein 551788 7681744 SPP_0609 Streptococcus pneumoniae P1031 ribonuclease III family protein YP_002737806.1 551402 D 488223 CDS YP_002737807.1 225856296 7682856 551792..552676 1 NC_012467.1 leucine-rich protein 552676 7682856 SPP_0610 Streptococcus pneumoniae P1031 leucine-rich protein YP_002737807.1 551792 D 488223 CDS YP_002737808.1 225856297 7681584 552724..552840 1 NC_012467.1 identified by glimmer; putative; hypothetical protein 552840 7681584 SPP_0611 Streptococcus pneumoniae P1031 hypothetical protein YP_002737808.1 552724 D 488223 CDS YP_002737809.1 225856298 7682721 553047..553412 1 NC_012467.1 identified by glimmer; putative; hypothetical protein 553412 7682721 SPP_0612 Streptococcus pneumoniae P1031 hypothetical protein YP_002737809.1 553047 D 488223 CDS YP_002737810.1 225856299 7681900 553558..553731 1 NC_012467.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop; GBSi1, group II intron, maturase 553731 7681900 SPP_0613 Streptococcus pneumoniae P1031 GBSi1, group II intron, maturase YP_002737810.1 553558 D 488223 CDS YP_002737811.1 225856300 7680710 554081..555358 1 NC_012467.1 identified by match to protein family HMM PF02687; peptide ABC transporter permease 555358 7680710 SPP_0614 Streptococcus pneumoniae P1031 peptide ABC transporter permease YP_002737811.1 554081 D 488223 CDS YP_002737812.1 225856301 7682328 555371..556018 1 NC_012467.1 identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 556018 7682328 SPP_0615 Streptococcus pneumoniae P1031 ABC transporter ATP-binding protein YP_002737812.1 555371 D 488223 CDS YP_002737813.1 225856302 7682481 556070..557449 1 NC_012467.1 identified by match to protein family HMM PF02687; peptide ABC transporter permease 557449 7682481 SPP_0616 Streptococcus pneumoniae P1031 peptide ABC transporter permease YP_002737813.1 556070 D 488223 CDS YP_002737814.1 225856303 7681248 557762..558418 1 NC_012467.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00486; VncR, response regulator 558418 7681248 SPP_0617 Streptococcus pneumoniae P1031 VncR, response regulator YP_002737814.1 557762 D 488223 CDS YP_002737815.1 225856304 7681278 558415..559743 1 NC_012467.1 identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518; VncS, histidine kinase 559743 7681278 SPP_0618 Streptococcus pneumoniae P1031 VncS, histidine kinase YP_002737815.1 558415 D 488223 CDS YP_002737816.1 225856305 7680948 559884..560765 1 NC_012467.1 catalyzes the formation of glycerone phosphate and glyceraldehyde 3-phosphate from fructose 1,6, bisphosphate; fructose-bisphosphate aldolase 560765 fba 7680948 fba Streptococcus pneumoniae P1031 fructose-bisphosphate aldolase YP_002737816.1 559884 D 488223 CDS YP_002737817.1 225856306 7681323 complement(562524..563183) 1 NC_012467.1 identified by match to protein family HMM PF00528; match to protein family HMM TIGR01726; glutamine ABC transporter permease 563183 7681323 SPP_0622 Streptococcus pneumoniae P1031 glutamine ABC transporter permease YP_002737817.1 562524 R 488223 CDS YP_002737818.1 225856307 7682395 complement(563193..563870) 1 NC_012467.1 identified by match to protein family HMM PF00528; match to protein family HMM TIGR01726; glutamine ABC transporter permease 563870 7682395 SPP_0623 Streptococcus pneumoniae P1031 glutamine ABC transporter permease YP_002737818.1 563193 R 488223 CDS YP_002737819.1 225856308 7681486 complement(563883..564677) 1 NC_012467.1 identified by match to protein family HMM PF00497; ABC transporter substrate-binding protein - glutamine transport/Major cell binding factor 564677 7681486 SPP_0624 Streptococcus pneumoniae P1031 ABC transporter substrate-binding protein - glutamine transport/Major cell binding factor YP_002737819.1 563883 R 488223 CDS YP_002737820.1 225856309 7681899 complement(564688..565446) 1 NC_012467.1 identified by match to protein family HMM PF00005; glutamine transport ATP-binding protein GlnQ 565446 7681899 SPP_0625 Streptococcus pneumoniae P1031 glutamine transport ATP-binding protein GlnQ YP_002737820.1 564688 R 488223 CDS YP_002737821.1 225856310 7681245 565711..567945 1 NC_012467.1 identified by match to protein family HMM PF01368; match to protein family HMM PF02272; match to protein family HMM TIGR00644; single-stranded-DNA-specific exonuclease RecJ 567945 recJ 7681245 recJ Streptococcus pneumoniae P1031 single-stranded-DNA-specific exonuclease RecJ YP_002737821.1 565711 D 488223 CDS YP_002737822.1 225856311 7680780 568120..569781 1 NC_012467.1 identified by match to protein family HMM PF00753; match to protein family HMM PF07521; metallo-beta-lactamase family protein 569781 7680780 SPP_0627 Streptococcus pneumoniae P1031 metallo-beta-lactamase family protein YP_002737822.1 568120 D 488223 CDS YP_002737823.1 225856312 7680900 569850..570629 1 NC_012467.1 identified by match to protein family HMM PF00756; tributyrin esterase 570629 7680900 SPP_0628 Streptococcus pneumoniae P1031 tributyrin esterase YP_002737823.1 569850 D 488223 CDS YP_002737824.1 225856313 7682243 570741..571961 1 NC_012467.1 identified by match to protein family HMM PF02388; serine/alanine-adding enzyme MurM 571961 7682243 SPP_0629 Streptococcus pneumoniae P1031 serine/alanine-adding enzyme MurM YP_002737824.1 570741 D 488223 CDS YP_002737825.1 225856314 7681662 571966..573198 1 NC_012467.1 identified by match to protein family HMM PF02388; alanine adding enzyme 573198 7681662 SPP_0630 Streptococcus pneumoniae P1031 alanine adding enzyme YP_002737825.1 571966 D 488223 CDS YP_002737826.1 225856315 7681917 573277..573978 1 NC_012467.1 identified by match to protein family HMM PF00413; matrixin family 573978 7681917 SPP_0631 Streptococcus pneumoniae P1031 matrixin family YP_002737826.1 573277 D 488223 CDS YP_002737827.1 225856316 7681613 574018..575862 1 NC_012467.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision; excinuclease ABC subunit C 575862 uvrC 7681613 uvrC Streptococcus pneumoniae P1031 excinuclease ABC subunit C YP_002737827.1 574018 D 488223 CDS YP_002737828.1 225856317 7682524 575852..576649 1 NC_012467.1 identified by match to protein family HMM PF00149; Ser/Thr protein phosphatase family protein 576649 7682524 SPP_0633 Streptococcus pneumoniae P1031 Ser/Thr protein phosphatase family protein YP_002737828.1 575852 D 488223 CDS YP_002737829.1 225856318 7681023 complement(576831..577631) 1 NC_012467.1 identified by match to protein family HMM PF00497; ABC transporter substrate-binding protein - glutamine transport/Major cell binding factor 577631 7681023 SPP_0634 Streptococcus pneumoniae P1031 ABC transporter substrate-binding protein - glutamine transport/Major cell binding factor YP_002737829.1 576831 R 488223 CDS YP_002737830.1 225856319 7680782 577675..577815 1 NC_012467.1 hypothetical protein 577815 7680782 SPP_0635 Streptococcus pneumoniae P1031 hypothetical protein YP_002737830.1 577675 D 488223 CDS YP_002737831.1 225856320 7681995 577802..578407 1 NC_012467.1 identified by match to protein family HMM PF00881; oxidoreductase 578407 7681995 SPP_0636 Streptococcus pneumoniae P1031 oxidoreductase YP_002737831.1 577802 D 488223 CDS YP_002737832.1 225856321 7680669 578420..579820 1 NC_012467.1 divalent metal ion-dependent extracellular dipeptidase; able to hydrolyze a broad range of dipeptides but no tri-, tetra-, or larger oligopeptides; differences in the amino acid specificity of the cleavage site varies between species; similar to succinyl-diaminopimelate desuccinylases; dipeptidase PepV 579820 pepV 7680669 pepV Streptococcus pneumoniae P1031 dipeptidase PepV YP_002737832.1 578420 D 488223 CDS YP_002737833.1 225856322 7682306 579874..580452 1 NC_012467.1 identified by match to protein family HMM PF03167; uracil DNA glycosylase family protein 580452 7682306 SPP_0638 Streptococcus pneumoniae P1031 uracil DNA glycosylase family protein YP_002737833.1 579874 D 488223 CDS YP_002737834.1 225856323 7681236 580612..580764 1 NC_012467.1 identified by glimmer; putative; hypothetical protein 580764 7681236 SPP_0639 Streptococcus pneumoniae P1031 hypothetical protein YP_002737834.1 580612 D 488223 CDS YP_002737835.1 225856324 7681888 580780..580899 1 NC_012467.1 identified by glimmer; putative; hypothetical protein 580899 7681888 SPP_0640 Streptococcus pneumoniae P1031 hypothetical protein YP_002737835.1 580780 D 488223 CDS YP_002737836.1 225856325 7680805 581070..582395 1 NC_012467.1 identified by match to protein family HMM PF05525; match to protein family HMM TIGR00796; branched-chain amino acid transport system II carrier protein 582395 brnQ 7680805 brnQ Streptococcus pneumoniae P1031 branched-chain amino acid transport system II carrier protein YP_002737836.1 581070 D 488223 CDS YP_002737837.1 225856326 7682690 582493..583530 1 NC_012467.1 identified by match to protein family HMM PF05343; peptidase, M42 583530 7682690 SPP_0642 Streptococcus pneumoniae P1031 peptidase, M42 YP_002737837.1 582493 D 488223 CDS YP_002737838.1 225856327 7681011 583532..583972 1 NC_012467.1 identified by match to protein family HMM PF01230; HIT family protein 583972 7681011 SPP_0643 Streptococcus pneumoniae P1031 HIT family protein YP_002737838.1 583532 D 488223 CDS YP_002737839.1 225856328 7681745 583980..584378 1 NC_012467.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; mobile genetic element 584378 7681745 SPP_0644 Streptococcus pneumoniae P1031 mobile genetic element YP_002737839.1 583980 D 488223 CDS YP_002737840.1 225856329 7680639 584395..584784 1 NC_012467.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by match to protein family HMM PF01609; transposase (IS4 family) 584784 7680639 SPP_0645 Streptococcus pneumoniae P1031 transposase (IS4 family) YP_002737840.1 584395 D 488223 CDS YP_002737841.1 225856330 7680980 584865..585581 1 NC_012467.1 identified by match to protein family HMM PF02557; D-alanyl-D-alanine carboxypeptidase 585581 7680980 SPP_0646 Streptococcus pneumoniae P1031 D-alanyl-D-alanine carboxypeptidase YP_002737841.1 584865 D 488223 CDS YP_002737842.1 225856331 7682506 complement(585621..585758) 1 NC_012467.1 identified by glimmer; putative; hypothetical protein 585758 7682506 SPP_0647 Streptococcus pneumoniae P1031 hypothetical protein YP_002737842.1 585621 R 488223 CDS YP_002737843.1 225856332 7682079 585890..586315 1 NC_012467.1 binds directly to 23S ribosomal RNA; 50S ribosomal protein L11 586315 rplK 7682079 rplK Streptococcus pneumoniae P1031 50S ribosomal protein L11 YP_002737843.1 585890 D 488223 CDS YP_002737844.1 225856333 7682262 586523..587212 1 NC_012467.1 in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA; 50S ribosomal protein L1 587212 rplA 7682262 rplA Streptococcus pneumoniae P1031 50S ribosomal protein L1 YP_002737844.1 586523 D 488223 CDS YP_002737845.1 225856334 7680713 complement(587858..588049) 1 NC_012467.1 chlorohydrolase 588049 7680713 SPP_0650 Streptococcus pneumoniae P1031 chlorohydrolase YP_002737845.1 587858 R 488223 CDS YP_002737846.1 225856335 7682064 589469..590461 1 NC_012467.1 identified by match to protein family HMM PF00005; polysaccharide ABC transporter ATP-binding protein 590461 7682064 SPP_0651 Streptococcus pneumoniae P1031 polysaccharide ABC transporter ATP-binding protein YP_002737846.1 589469 D 488223 CDS YP_002737847.1 225856336 7681519 590463..591281 1 NC_012467.1 identified by match to protein family HMM PF06182; membrane protein 591281 7681519 SPP_0652 Streptococcus pneumoniae P1031 membrane protein YP_002737847.1 590463 D 488223 CDS YP_002737848.1 225856337 7681680 591283..592068 1 NC_012467.1 identified by match to protein family HMM PF06182; ABC transporter permease 592068 7681680 SPP_0653 Streptococcus pneumoniae P1031 ABC transporter permease YP_002737848.1 591283 D 488223 CDS YP_002737849.1 225856338 7681340 complement(592885..593067) 1 NC_012467.1 chlorohydrolase 593067 7681340 SPP_0656 Streptococcus pneumoniae P1031 chlorohydrolase YP_002737849.1 592885 R 488223 CDS YP_002737850.1 225856339 7682724 593300..599731 1 NC_012467.1 identified by match to protein family HMM PF00082; match to protein family HMM PF00746; match to protein family HMM PF02225; match to protein family HMM PF06280; match to protein family HMM TIGR01167; serine protease 599731 7682724 SPP_0657 Streptococcus pneumoniae P1031 serine protease YP_002737850.1 593300 D 488223 CDS YP_002737851.1 225856340 7682456 602119..602595 1 NC_012467.1 identified by match to protein family HMM PF00359; phosphotransferase system sugar-specific EII component 602595 7682456 SPP_0661 Streptococcus pneumoniae P1031 phosphotransferase system sugar-specific EII component YP_002737851.1 602119 D 488223 CDS YP_002737852.1 225856341 7681338 602633..602938 1 NC_012467.1 PTS system, galactose-specific IIB component 602938 7681338 SPP_0662 Streptococcus pneumoniae P1031 PTS system, galactose-specific IIB component YP_002737852.1 602633 D 488223 CDS YP_002737853.1 225856342 7682278 602986..604461 1 NC_012467.1 identified by match to protein family HMM PF03611; phosphotransferase system sugar-specific EII component 604461 7682278 SPP_0663 Streptococcus pneumoniae P1031 phosphotransferase system sugar-specific EII component YP_002737853.1 602986 D 488223 CDS YP_002737854.1 225856343 7680701 604487..604633 1 NC_012467.1 chlorohydrolase 604633 7680701 SPP_0664 Streptococcus pneumoniae P1031 chlorohydrolase YP_002737854.1 604487 D 488223 CDS YP_002737855.1 225856344 7682859 604721..611422 1 NC_012467.1 identified by match to protein family HMM PF00703; match to protein family HMM PF00746; match to protein family HMM PF02836; match to protein family HMM PF02837; match to protein family HMM PF04650; match to protein family HMM PF07501; match to protein family HMM PF07532; match to protein family HMM TIGR01167; match to protein family HMM TIGR01168; beta-galactosidase 611422 7682859 SPP_0665 Streptococcus pneumoniae P1031 beta-galactosidase YP_002737855.1 604721 D 488223 CDS YP_002737856.1 225856345 7682610 complement(611670..612293) 1 NC_012467.1 identified by glimmer; putative; hypothetical protein 612293 7682610 SPP_0666 Streptococcus pneumoniae P1031 hypothetical protein YP_002737856.1 611670 R 488223 CDS YP_002737857.1 225856346 7681097 complement(612281..612526) 1 NC_012467.1 identified by glimmer; putative; hypothetical protein 612526 7681097 SPP_0667 Streptococcus pneumoniae P1031 hypothetical protein YP_002737857.1 612281 R 488223 CDS YP_002737858.1 225856347 7682189 complement(612737..613096) 1 NC_012467.1 integral membrane protein 613096 7682189 SPP_0668 Streptococcus pneumoniae P1031 integral membrane protein YP_002737858.1 612737 R 488223 CDS YP_002737859.1 225856348 7681152 614677..614931 1 NC_012467.1 hypothetical protein 614931 7681152 SPP_0674 Streptococcus pneumoniae P1031 hypothetical protein YP_002737859.1 614677 D 488223 CDS YP_002737860.1 225856349 7682836 614943..616997 1 NC_012467.1 identified by match to protein family HMM PF00999; sodium/hydrogen exchanger family protein 616997 7682836 SPP_0675 Streptococcus pneumoniae P1031 sodium/hydrogen exchanger family protein YP_002737860.1 614943 D 488223 CDS YP_002737861.1 225856350 7682164 complement(617030..617143) 1 NC_012467.1 identified by glimmer; putative; hypothetical protein 617143 7682164 SPP_0676 Streptococcus pneumoniae P1031 hypothetical protein YP_002737861.1 617030 R 488223 CDS YP_002737862.1 225856351 7681750 617176..618036 1 NC_012467.1 identified by match to protein family HMM PF03631; ribonuclease BN 618036 7681750 SPP_0677 Streptococcus pneumoniae P1031 ribonuclease BN YP_002737862.1 617176 D 488223 CDS YP_002737863.1 225856352 7682618 618255..618965 1 NC_012467.1 identified by match to protein family HMM PF02683; cytoChrome c-type biogenesis protein 618965 7682618 SPP_0678 Streptococcus pneumoniae P1031 cytoChrome c-type biogenesis protein YP_002737863.1 618255 D 488223 CDS YP_002737864.1 225856353 7680986 618985..619551 1 NC_012467.1 identified by match to protein family HMM PF00578; match to protein family HMM PF08534; thioredoxin family protein 619551 7680986 SPP_0679 Streptococcus pneumoniae P1031 thioredoxin family protein YP_002737864.1 618985 D 488223 CDS YP_002737865.1 225856354 7681419 619562..620674 1 NC_012467.1 identified by match to protein family HMM PF01625; match to protein family HMM PF01641; match to protein family HMM TIGR00357; match to protein family HMM TIGR00401; peptide methionine sulfoxide reductase MsrA/msrB 620674 7681419 SPP_0680 Streptococcus pneumoniae P1031 peptide methionine sulfoxide reductase MsrA/msrB YP_002737865.1 619562 D 488223 CDS YP_002737866.1 225856355 7682659 620987..621724 1 NC_012467.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00165; response regulator 621724 7682659 SPP_0681 Streptococcus pneumoniae P1031 response regulator YP_002737866.1 620987 D 488223 CDS YP_002737867.1 225856356 7680991 621721..623412 1 NC_012467.1 identified by match to protein family HMM PF00672; match to protein family HMM PF02518; match to protein family HMM PF02743; match to protein family HMM PF06580; histidine kinase 623412 7680991 SPP_0682 Streptococcus pneumoniae P1031 histidine kinase YP_002737867.1 621721 D 488223 CDS YP_002737868.1 225856357 7681284 623528..624091 1 NC_012467.1 identified by match to protein family HMM PF04260; match to protein family HMM TIGR01440; hypothetical protein 624091 7681284 SPP_0683 Streptococcus pneumoniae P1031 hypothetical protein YP_002737868.1 623528 D 488223 CDS YP_002737869.1 225856358 7680834 624113..629755 1 NC_012467.1 identified by match to protein family HMM PF00746; match to protein family HMM PF05342; match to protein family HMM PF07501; match to protein family HMM PF07580; match to protein family HMM TIGR01167; zinc metalloprotease ZmpB 629755 zmpB1 7680834 zmpB1 Streptococcus pneumoniae P1031 zinc metalloprotease ZmpB YP_002737869.1 624113 D 488223 CDS YP_002737870.1 225856359 7681593 629816..631537 1 NC_012467.1 identified by match to protein family HMM PF00425; match to protein family HMM TIGR00553; chorismate binding enzyme 631537 7681593 SPP_0685 Streptococcus pneumoniae P1031 chorismate binding enzyme YP_002737870.1 629816 D 488223 CDS YP_002737871.1 225856360 7681303 631538..632155 1 NC_012467.1 hypothetical protein 632155 7681303 SPP_0686 Streptococcus pneumoniae P1031 hypothetical protein YP_002737871.1 631538 D 488223 CDS YP_002737872.1 225856361 7682265 633329..634288 1 NC_012467.1 identified by match to protein family HMM PF00480; match to protein family HMM TIGR00744; glucokinase (Glucose kinase) 634288 7682265 SPP_0689 Streptococcus pneumoniae P1031 glucokinase (Glucose kinase) YP_002737872.1 633329 D 488223 CDS YP_002737873.1 225856362 7680671 634385..635224 1 NC_012467.1 ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived; thymidylate synthase 635224 thyA 7680671 thyA Streptococcus pneumoniae P1031 thymidylate synthase YP_002737873.1 634385 D 488223 CDS YP_002737874.1 225856363 7681158 complement(635272..635442) 1 NC_012467.1 hypothetical protein 635442 7681158 SPP_0691 Streptococcus pneumoniae P1031 hypothetical protein YP_002737874.1 635272 R 488223 CDS YP_002737875.1 225856364 7680909 635563..636447 1 NC_012467.1 IPP transferase; isopentenyltransferase; involved in tRNA modification; in Escherichia coli this enzyme catalyzes the addition of a delta2-isopentenyl group from dimethylallyl diphosphate to the N6-nitrogen of adenosine adjacent to the anticodon of tRNA species that read codons starting with uracil; further tRNA modifications may occur; mutations in miaA result in defects in translation efficiency and fidelity; tRNA delta(2)-isopentenylpyrophosphate transferase 636447 miaA 7680909 miaA Streptococcus pneumoniae P1031 tRNA delta(2)-isopentenylpyrophosphate transferase YP_002737875.1 635563 D 488223 CDS YP_002737876.1 225856365 7682714 636440..637678 1 NC_012467.1 identified by match to protein family HMM PF01926; match to protein family HMM TIGR00231; match to protein family HMM TIGR03156; GTP-binding proten HflX 637678 hflX 7682714 hflX Streptococcus pneumoniae P1031 GTP-binding proten HflX YP_002737876.1 636440 D 488223 CDS YP_002737877.1 225856366 7682663 637671..638294 1 NC_012467.1 cystathionine beta-lyase 638294 7682663 SPP_0694 Streptococcus pneumoniae P1031 cystathionine beta-lyase YP_002737877.1 637671 D 488223 CDS YP_002737878.1 225856367 7680895 638309..639238 1 NC_012467.1 member of metallo-beta-lactamase family; the purified enzyme from Escherichia coli forms dimeric zinc phosphodiesterase; in Bacillus subtilis this protein is a 3'-tRNA processing endoribonuclease and is essential while in Escherichia coli it is not; associates with two zinc ions; ribonuclease Z 639238 rnz 7680895 rnz Streptococcus pneumoniae P1031 ribonuclease Z YP_002737878.1 638309 D 488223 CDS YP_002737879.1 225856368 7681298 639259..640014 1 NC_012467.1 identified by match to protein family HMM PF00106; match to protein family HMM PF08659; oxidoreductase 640014 7681298 SPP_0696 Streptococcus pneumoniae P1031 oxidoreductase YP_002737879.1 639259 D 488223 CDS YP_002737880.1 225856369 7681594 complement(640068..641036) 1 NC_012467.1 identified by match to protein family HMM PF00126; regulatory function on capsule expression 641036 7681594 SPP_0697 Streptococcus pneumoniae P1031 regulatory function on capsule expression YP_002737880.1 640068 R 488223 CDS YP_002737881.1 225856370 7680626 641040..641309 1 NC_012467.1 identified by match to protein family HMM PF06014; hypothetical protein 641309 7680626 SPP_0698 Streptococcus pneumoniae P1031 hypothetical protein YP_002737881.1 641040 D 488223 CDS YP_002737882.1 225856371 7682574 641309..641689 1 NC_012467.1 identified by match to protein family HMM PF00581; rhodanese family protein 641689 7682574 SPP_0699 Streptococcus pneumoniae P1031 rhodanese family protein YP_002737882.1 641309 D 488223 CDS YP_002737883.1 225856372 7681216 641778..642005 1 NC_012467.1 hypothetical protein 642005 7681216 SPP_0700 Streptococcus pneumoniae P1031 hypothetical protein YP_002737883.1 641778 D 488223 CDS YP_002737884.1 225856373 7681148 complement(642045..642770) 1 NC_012467.1 identified by match to protein family HMM PF00849; match to protein family HMM PF01479; match to protein family HMM TIGR00093; ribosomal small subunit pseudouridine synthase A, putative 642770 7681148 SPP_0701 Streptococcus pneumoniae P1031 ribosomal small subunit pseudouridine synthase A, putative YP_002737884.1 642045 R 488223 CDS YP_002737885.1 225856374 7682233 642911..644773 1 NC_012467.1 identified by match to protein family HMM PF00009; match to protein family HMM PF00679; match to protein family HMM PF03144; match to protein family HMM TIGR00231; match to protein family HMM TIGR01394; GTP-binding protein TypA/BipA 644773 typA 7682233 typA Streptococcus pneumoniae P1031 GTP-binding protein TypA/BipA YP_002737885.1 642911 D 488223 CDS YP_002737886.1 225856375 7682034 644793..645047 1 NC_012467.1 hypothetical protein 645047 7682034 SPP_0703 Streptococcus pneumoniae P1031 hypothetical protein YP_002737886.1 644793 D 488223 CDS YP_002737887.1 225856376 7681044 645413..645712 1 NC_012467.1 identified by match to protein family HMM TIGR01653; bacteriocin, lactococcin 972 family 645712 7681044 SPP_0704 Streptococcus pneumoniae P1031 bacteriocin, lactococcin 972 family YP_002737887.1 645413 D 488223 CDS YP_002737888.1 225856377 7681954 645950..647803 1 NC_012467.1 identified by match to protein family HMM PF07242; match to protein family HMM TIGR01654; bacteriocin-associated integral membrane protein 647803 7681954 SPP_0705 Streptococcus pneumoniae P1031 bacteriocin-associated integral membrane protein YP_002737888.1 645950 D 488223 CDS YP_002737889.1 225856378 7682637 647805..648446 1 NC_012467.1 identified by match to protein family HMM PF00005; Na+ ABC transporter ATP-binding protein 648446 7682637 SPP_0706 Streptococcus pneumoniae P1031 Na+ ABC transporter ATP-binding protein YP_002737889.1 647805 D 488223 CDS YP_002737890.1 225856379 7681166 648550..649902 1 NC_012467.1 UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase 649902 murD 7681166 murD Streptococcus pneumoniae P1031 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase YP_002737890.1 648550 D 488223 CDS YP_002737891.1 225856380 7682499 649904..650962 1 NC_012467.1 UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; involved in cell wall formation; inner membrane-associated; last step of peptidoglycan synthesis; UDP diphospho-muramoyl pentapeptide beta-N acetylglucosaminyl transferase 650962 murG 7682499 murG Streptococcus pneumoniae P1031 UDP diphospho-muramoyl pentapeptide beta-N acetylglucosaminyl transferase YP_002737891.1 649904 D 488223 CDS YP_002737892.1 225856381 7681117 650972..652171 1 NC_012467.1 identified by match to protein family HMM PF03799; match to protein family HMM PF08478; cell division protein DivIB 652171 7681117 SPP_0709 Streptococcus pneumoniae P1031 cell division protein DivIB YP_002737892.1 650972 D 488223 CDS YP_002737893.1 225856382 7681914 652404..653105 1 NC_012467.1 type 1 subfamily; involved in last step of pyrimidine biosynthesis; converts orotidine 5'-phosphate to UMP and carbon dioxide; OMP decarboxylase; OMPDCase; OMPdecase; orotidine 5'-phosphate decarboxylase 653105 pyrF 7681914 pyrF Streptococcus pneumoniae P1031 orotidine 5'-phosphate decarboxylase YP_002737893.1 652404 D 488223 CDS YP_002737894.1 225856383 7682840 653139..653771 1 NC_012467.1 involved in fifth step of pyrimidine biosynthesis; converts orotidine 5'-phosphate and diphosphate to orotate and 5-phospho-alpha-D-ribose 1-diphosphate; orotate phosphoribosyltransferase 653771 pyrE 7682840 pyrE Streptococcus pneumoniae P1031 orotate phosphoribosyltransferase YP_002737894.1 653139 D 488223 CDS YP_002737895.1 225856384 7681792 654232..654354 1 NC_012467.1 identified by glimmer; putative; hypothetical protein 654354 7681792 SPP_0712 Streptococcus pneumoniae P1031 hypothetical protein YP_002737895.1 654232 D 488223 CDS YP_002737896.1 225856385 7681057 654450..655214 1 NC_012467.1 hypothetical protein 655214 7681057 SPP_0713 Streptococcus pneumoniae P1031 hypothetical protein YP_002737896.1 654450 D 488223 CDS YP_002737897.1 225856386 7681454 655214..655966 1 NC_012467.1 lipoprotein, putative 655966 7681454 SPP_0714 Streptococcus pneumoniae P1031 lipoprotein, putative YP_002737897.1 655214 D 488223 CDS YP_002737898.1 225856387 7682566 655970..656674 1 NC_012467.1 hypothetical protein 656674 7682566 SPP_0715 Streptococcus pneumoniae P1031 hypothetical protein YP_002737898.1 655970 D 488223 CDS YP_002737899.1 225856388 7681155 656671..657318 1 NC_012467.1 identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 657318 7681155 SPP_0716 Streptococcus pneumoniae P1031 ABC transporter ATP-binding protein YP_002737899.1 656671 D 488223 CDS YP_002737900.1 225856389 7681279 complement(657405..658271) 1 NC_012467.1 identified by match to protein family HMM PF00497; ABC-type amino acid transport/signal transduction system, periplasmic component/domain protein 658271 7681279 SPP_0717 Streptococcus pneumoniae P1031 ABC-type amino acid transport/signal transduction system, periplasmic component/domain protein YP_002737900.1 657405 R 488223 CDS YP_002737901.1 225856390 7682493 complement(659689..660309) 1 NC_012467.1 identified by match to protein family HMM PF00528; match to protein family HMM TIGR01726; glutamine ABC transporter permease 660309 7682493 SPP_0722 Streptococcus pneumoniae P1031 glutamine ABC transporter permease YP_002737901.1 659689 R 488223 CDS YP_002737902.1 225856391 7682002 660584..660730 1 NC_012467.1 hypothetical protein 660730 7682002 SPP_0723 Streptococcus pneumoniae P1031 hypothetical protein YP_002737902.1 660584 D 488223 CDS YP_002737903.1 225856392 7681718 660858..662348 1 NC_012467.1 class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1; lysyl-tRNA synthetase 662348 lysS 7681718 lysS Streptococcus pneumoniae P1031 lysyl-tRNA synthetase YP_002737903.1 660858 D 488223 CDS YP_002737904.1 225856393 7682766 662973..664109 1 NC_012467.1 identified by match to protein family HMM PF01070; match to protein family HMM TIGR02708; L-lactate oxidase 664109 lctO 7682766 lctO Streptococcus pneumoniae P1031 L-lactate oxidase YP_002737904.1 662973 D 488223 CDS YP_002737905.1 225856394 7681025 complement(665389..665520) 1 NC_012467.1 identified by glimmer; putative; hypothetical protein 665520 7681025 SPP_0727 Streptococcus pneumoniae P1031 hypothetical protein YP_002737905.1 665389 R 488223 CDS YP_002737906.1 225856395 7680935 665616..666398 1 NC_012467.1 catalyzes the formation of 4-methyl-5-(2-phosphoethyl)-thiazole and ADP from 4-methyl-5-(2-hydroxyethyl)-thiazole and ATP; hydroxyethylthiazole kinase 666398 thiM 7680935 thiM Streptococcus pneumoniae P1031 hydroxyethylthiazole kinase YP_002737906.1 665616 D 488223 CDS YP_002737907.1 225856396 7682449 666400..667029 1 NC_012467.1 identified by match to protein family HMM PF02581; match to protein family HMM TIGR00693; thiamine-phosphate pyrophosphorylase 667029 thiE1 7682449 thiE1 Streptococcus pneumoniae P1031 thiamine-phosphate pyrophosphorylase YP_002737907.1 666400 D 488223 CDS YP_002737908.1 225856397 7682715 667588..668148 1 NC_012467.1 cobalt ABC transporter permease 668148 7682715 SPP_0730 Streptococcus pneumoniae P1031 cobalt ABC transporter permease YP_002737908.1 667588 D 488223 CDS YP_002737909.1 225856398 7682143 668149..669534 1 NC_012467.1 identified by match to protein family HMM PF00005; cobalt ABC transporter ATP-binding protein 669534 7682143 SPP_0731 Streptococcus pneumoniae P1031 cobalt ABC transporter ATP-binding protein YP_002737909.1 668149 D 488223 CDS YP_002737910.1 225856399 7680813 669536..670186 1 NC_012467.1 hypothetical protein 670186 7680813 SPP_0732 Streptococcus pneumoniae P1031 hypothetical protein YP_002737910.1 669536 D 488223 CDS YP_002737911.1 225856400 7681035 670197..670889 1 NC_012467.1 identified by match to protein family HMM PF03070; tena/thi-4 family 670889 7681035 SPP_0733 Streptococcus pneumoniae P1031 tena/thi-4 family YP_002737911.1 670197 D 488223 CDS YP_002737912.1 225856401 7680916 670894..671418 1 NC_012467.1 identified by match to protein family HMM TIGR02359; ThiW protein 671418 thiW 7680916 thiW Streptococcus pneumoniae P1031 ThiW protein YP_002737912.1 670894 D 488223 CDS YP_002737913.1 225856402 7681647 671418..672221 1 NC_012467.1 identified by match to protein family HMM PF02110; hydroxyethylthiazole kinase 672221 7681647 SPP_0735 Streptococcus pneumoniae P1031 hydroxyethylthiazole kinase YP_002737913.1 671418 D 488223 CDS YP_002737914.1 225856403 7681849 672214..672846 1 NC_012467.1 Condenses 4-methyl-5-(beta-hydroxyethyl)-thiazole monophosphate and 4-amino-5-hydroxymethyl pyrimidine pyrophosphate to form thiamine monophosphate; thiamine-phosphate pyrophosphorylase 672846 thiE 7681849 thiE Streptococcus pneumoniae P1031 thiamine-phosphate pyrophosphorylase YP_002737914.1 672214 D 488223 CDS YP_002737915.1 225856404 7682587 complement(673055..673846) 1 NC_012467.1 catalyzes the formation of 4-amino-2-methyl-5-diphosphomethylpyrimidine; phosphomethylpyrimidine kinase 673846 thiD 7682587 thiD Streptococcus pneumoniae P1031 phosphomethylpyrimidine kinase YP_002737915.1 673055 R 488223 CDS YP_002737916.1 225856405 7681164 674212..674607 1 NC_012467.1 identified by match to protein family HMM PF03965; match to protein family HMM TIGR02698; copper transport repressor, CopY/TcrY family 674607 7681164 SPP_0738 Streptococcus pneumoniae P1031 copper transport repressor, CopY/TcrY family YP_002737916.1 674212 D 488223 CDS YP_002737917.1 225856406 7682038 674618..674989 1 NC_012467.1 hypothetical protein 674989 7682038 SPP_0739 Streptococcus pneumoniae P1031 hypothetical protein YP_002737917.1 674618 D 488223 CDS YP_002737918.1 225856407 7680823 674999..677242 1 NC_012467.1 identified by match to protein family HMM PF00122; match to protein family HMM PF00702; match to protein family HMM PF08282; match to protein family HMM TIGR01494; match to protein family HMM TIGR01511; match to protein family HMM TIGR01525; copper-translocating P-type ATPase 677242 7680823 SPP_0740 Streptococcus pneumoniae P1031 copper-translocating P-type ATPase YP_002737918.1 674999 D 488223 CDS YP_002737919.1 225856408 7681180 677449..679224 1 NC_012467.1 identified by match to protein family HMM PF00205; match to protein family HMM PF02775; match to protein family HMM PF02776; match to protein family HMM TIGR02720; pyruvate oxidase 679224 spxB 7681180 spxB Streptococcus pneumoniae P1031 pyruvate oxidase YP_002737919.1 677449 D 488223 CDS YP_002737920.1 225856409 7682514 679335..679682 1 NC_012467.1 identified by match to protein family HMM PF00903; glyoxalase family protein 679682 7682514 SPP_0742 Streptococcus pneumoniae P1031 glyoxalase family protein YP_002737920.1 679335 D 488223 CDS YP_002737921.1 225856410 7682067 complement(679799..679960) 1 NC_012467.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; transposase 679960 7682067 SPP_0743 Streptococcus pneumoniae P1031 transposase YP_002737921.1 679799 R 488223 CDS YP_002737922.1 225856411 7681229 complement(679954..680388) 1 NC_012467.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; transposase 680388 7681229 SPP_0744 Streptococcus pneumoniae P1031 transposase YP_002737922.1 679954 R 488223 CDS YP_002737923.1 225856412 7681925 complement(680339..680845) 1 NC_012467.1 transposase 680845 7681925 SPP_0745 Streptococcus pneumoniae P1031 transposase YP_002737923.1 680339 R 488223 CDS YP_002737924.1 225856413 7681994 680910..681191 1 NC_012467.1 6-phospho-beta-glucosidase AscB, truncation 681191 7681994 SPP_0746 Streptococcus pneumoniae P1031 6-phospho-beta-glucosidase AscB, truncation YP_002737924.1 680910 D 488223 CDS YP_002737925.1 225856414 7681554 681323..682267 1 NC_012467.1 identified by match to protein family HMM PF01238; match to protein family HMM TIGR00218; mannose-6-phosphate isomerase, class I 682267 manA 7681554 manA Streptococcus pneumoniae P1031 mannose-6-phosphate isomerase, class I YP_002737925.1 681323 D 488223 CDS YP_002737926.1 225856415 7681406 683867..684607 1 NC_012467.1 identified by match to protein family HMM PF00376; match to protein family HMM PF07739; match to protein family HMM PF09278; transcriptional regulator, MerR family 684607 7681406 SPP_0750 Streptococcus pneumoniae P1031 transcriptional regulator, MerR family YP_002737926.1 683867 D 488223 CDS YP_002737927.1 225856416 7682339 complement(684636..685058) 1 NC_012467.1 identified by match to protein family HMM PF00293; MutT/nudix family protein 685058 7682339 SPP_0751 Streptococcus pneumoniae P1031 MutT/nudix family protein YP_002737927.1 684636 R 488223 CDS YP_002737928.1 225856417 7681945 complement(685111..686286) 1 NC_012467.1 identified by match to protein family HMM PF03486; match to protein family HMM TIGR00275; hypothetical protein 686286 7681945 SPP_0752 Streptococcus pneumoniae P1031 hypothetical protein YP_002737928.1 685111 R 488223 CDS YP_002737929.1 225856418 7680779 complement(686345..687190) 1 NC_012467.1 identified by match to protein family HMM PF02645; match to protein family HMM TIGR00762; hypothetical protein 687190 7680779 SPP_0753 Streptococcus pneumoniae P1031 hypothetical protein YP_002737929.1 686345 R 488223 CDS YP_002737930.1 225856419 7681814 687315..687872 1 NC_012467.1 identified by match to protein family HMM PF00440; TetR family transcriptional regulator 687872 7681814 SPP_0754 Streptococcus pneumoniae P1031 TetR family transcriptional regulator YP_002737930.1 687315 D 488223 CDS YP_002737931.1 225856420 7681686 687891..688358 1 NC_012467.1 identified by match to protein family HMM PF00383; ComE operon protein 2 688358 7681686 SPP_0755 Streptococcus pneumoniae P1031 ComE operon protein 2 YP_002737931.1 687891 D 488223 CDS YP_002737932.1 225856421 7682291 688424..689074 1 NC_012467.1 Catalyzes the formation of uracil and 5-phospho-alpha-D-ribosy 1-diphosphate from UMP and diphosphate; uracil phosphoribosyltransferase 689074 upp 7682291 upp Streptococcus pneumoniae P1031 uracil phosphoribosyltransferase YP_002737932.1 688424 D 488223 CDS YP_002737933.1 225856422 7682798 689248..689838 1 NC_012467.1 hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates; ATP-dependent Clp protease proteolytic subunit 689838 clpP 7682798 clpP Streptococcus pneumoniae P1031 ATP-dependent Clp protease proteolytic subunit YP_002737933.1 689248 D 488223 CDS YP_002737934.1 225856423 7682042 689917..690165 1 NC_012467.1 hypothetical protein 690165 7682042 SPP_0758 Streptococcus pneumoniae P1031 hypothetical protein YP_002737934.1 689917 D 488223 CDS YP_002737935.1 225856424 7681075 690266..691426 1 NC_012467.1 identified by match to protein family HMM PF01094; ABC transporter substrate-binding protein - branched chain amino acid transport 691426 7681075 SPP_0759 Streptococcus pneumoniae P1031 ABC transporter substrate-binding protein - branched chain amino acid transport YP_002737935.1 690266 D 488223 CDS YP_002737936.1 225856425 7681377 complement(691513..691626) 1 NC_012467.1 identified by glimmer; putative; hypothetical protein 691626 7681377 SPP_0760 Streptococcus pneumoniae P1031 hypothetical protein YP_002737936.1 691513 R 488223 CDS YP_002737937.1 225856426 7682487 691694..692563 1 NC_012467.1 identified by match to protein family HMM PF02653; high-affinity branched-chain amino acid transport system permeaseprotein LivH (LIV-I protein H) 692563 7682487 SPP_0761 Streptococcus pneumoniae P1031 high-affinity branched-chain amino acid transport system permeaseprotein LivH (LIV-I protein H) YP_002737937.1 691694 D 488223 CDS YP_002737938.1 225856427 7681965 692567..693523 1 NC_012467.1 identified by match to protein family HMM PF02653; branched-chain amino acid ABC transporter permease 693523 7681965 SPP_0762 Streptococcus pneumoniae P1031 branched-chain amino acid ABC transporter permease YP_002737938.1 692567 D 488223 CDS YP_002737939.1 225856428 7680691 693523..694287 1 NC_012467.1 identified by match to protein family HMM PF00005; high-affinity branched-chain amino acid transport ATP-binding proteinlivG (LIV-I protein G) 694287 7680691 SPP_0763 Streptococcus pneumoniae P1031 high-affinity branched-chain amino acid transport ATP-binding proteinlivG (LIV-I protein G) YP_002737939.1 693523 D 488223 CDS YP_002737940.1 225856429 7680854 694287..694997 1 NC_012467.1 identified by match to protein family HMM PF00005; high-affinity branched-chain amino acid transport ATP-binding proteinlivF (LIV-I protein F) 694997 7680854 SPP_0764 Streptococcus pneumoniae P1031 high-affinity branched-chain amino acid transport ATP-binding proteinlivF (LIV-I protein F) YP_002737940.1 694287 D 488223 CDS YP_002737941.1 225856430 7682268 695305..695961 1 NC_012467.1 identified by match to protein family HMM PF00571; AcuB family protein 695961 7682268 SPP_0765 Streptococcus pneumoniae P1031 AcuB family protein YP_002737941.1 695305 D 488223 CDS YP_002737942.1 225856431 7680700 696175..697164 1 NC_012467.1 recognizes the termination signals UGA and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF2; in some organisms control of PrfB protein levels is maintained through a +1 ribosomal frameshifting mechanism; this protein is similar to release factor 1; peptide chain release factor 2 697164 prfB 7680700 prfB Streptococcus pneumoniae P1031 peptide chain release factor 2 YP_002737942.1 696175 D 488223 CDS YP_002737943.1 225856432 7681197 697182..697874 1 NC_012467.1 identified by match to protein family HMM PF00005; match to protein family HMM TIGR02673; cell division ATP-binding protein FtsE 697874 ftsE 7681197 ftsE Streptococcus pneumoniae P1031 cell division ATP-binding protein FtsE YP_002737943.1 697182 D 488223 CDS YP_002737944.1 225856433 7682533 697867..698793 1 NC_012467.1 identified by match to protein family HMM PF02687; cell division ABC transporter, permease protein FtsX 698793 7682533 SPP_0768 Streptococcus pneumoniae P1031 cell division ABC transporter, permease protein FtsX YP_002737944.1 697867 D 488223 CDS YP_002737945.1 225856434 7682060 699079..701259 1 NC_012467.1 identified by match to protein family HMM PF00358; match to protein family HMM PF00367; match to protein family HMM PF02378; match to protein family HMM TIGR00826; match to protein family HMM TIGR00830; match to protein family HMM TIGR02003; pts system, iibc component 701259 7682060 SPP_0769 Streptococcus pneumoniae P1031 pts system, iibc component YP_002737945.1 699079 D 488223 CDS YP_002737946.1 225856435 7681014 701311..702126 1 NC_012467.1 identified by match to protein family HMM PF03372; metal-dependent hydrolase 702126 7681014 SPP_0770 Streptococcus pneumoniae P1031 metal-dependent hydrolase YP_002737946.1 701311 D 488223 CDS YP_002737947.1 225856436 7682311 702266..703609 1 NC_012467.1 identified by match to protein family HMM PF00270; match to protein family HMM PF00271; ATP-dependent RNA helicase 703609 7682311 SPP_0771 Streptococcus pneumoniae P1031 ATP-dependent RNA helicase YP_002737947.1 702266 D 488223 CDS YP_002737948.1 225856437 7680822 703986..705176 1 NC_012467.1 catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase; S-adenosylmethionine synthetase 705176 metK 7680822 metK Streptococcus pneumoniae P1031 S-adenosylmethionine synthetase YP_002737948.1 703986 D 488223 CDS YP_002737949.1 225856438 7682511 705729..706664 1 NC_012467.1 catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway; subclass 1A is a dimer formed by two identical PyrD subunits each containing an FMN group; dihydroorotate dehydrogenase 1A 706664 7682511 SPP_0773 Streptococcus pneumoniae P1031 dihydroorotate dehydrogenase 1A YP_002737949.1 705729 D 488223 CDS YP_002737950.1 225856439 7681120 706698..707735 1 NC_012467.1 required for the assembly and function of the DNAX complex which is required for the assembly of the beta subunit onto primed DNA; DNA polymerase III subunit delta 707735 holA 7681120 holA Streptococcus pneumoniae P1031 DNA polymerase III subunit delta YP_002737950.1 706698 D 488223 CDS YP_002737951.1 225856440 7682053 707908..708513 1 NC_012467.1 identified by match to protein family HMM PF00081; match to protein family HMM PF02777; superoxide dismutase [Mn] (General stress protein 24)(GSP24) 708513 7682053 SPP_0775 Streptococcus pneumoniae P1031 superoxide dismutase [Mn] (General stress protein 24)(GSP24) YP_002737951.1 707908 D 488223 CDS YP_002737952.1 225856441 7682392 708669..709199 1 NC_012467.1 identified by match to protein family HMM PF06265; transcriptional regulator 709199 7682392 SPP_0776 Streptococcus pneumoniae P1031 transcriptional regulator YP_002737952.1 708669 D 488223 CDS YP_002737953.1 225856442 7681316 709220..710305 1 NC_012467.1 23S rRNA m2A2503 methyltransferase; methylates the C2 position of the A2530 nucleotide in 23S rRNA; may be involved in antibiotic resistance; ribosomal RNA large subunit methyltransferase N 710305 7681316 SPP_0777 Streptococcus pneumoniae P1031 ribosomal RNA large subunit methyltransferase N YP_002737953.1 709220 D 488223 CDS YP_002737954.1 225856443 7682048 710305..710787 1 NC_012467.1 identified by match to protein family HMM PF04892; VanZ family protein 710787 7682048 SPP_0778 Streptococcus pneumoniae P1031 VanZ family protein YP_002737954.1 710305 D 488223 CDS YP_002737955.1 225856444 7682218 710789..712330 1 NC_012467.1 identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 712330 7682218 SPP_0779 Streptococcus pneumoniae P1031 ABC transporter ATP-binding protein YP_002737955.1 710789 D 488223 CDS YP_002737956.1 225856445 7681453 complement(712386..713189) 1 NC_012467.1 identified by match to protein family HMM PF00160; peptidyl-prolyl cis-trans isomerase, cyclophilin-type 713189 7681453 SPP_0780 Streptococcus pneumoniae P1031 peptidyl-prolyl cis-trans isomerase, cyclophilin-type YP_002737956.1 712386 R 488223 CDS YP_002737957.1 225856446 7682646 complement(713272..713493) 1 NC_012467.1 hypothetical protein 713493 7682646 SPP_0781 Streptococcus pneumoniae P1031 hypothetical protein YP_002737957.1 713272 R 488223 CDS YP_002737958.1 225856447 7682867 complement(713972..714181) 1 NC_012467.1 identified by glimmer; putative; hypothetical protein 714181 7682867 SPP_0782 Streptococcus pneumoniae P1031 hypothetical protein YP_002737958.1 713972 R 488223 CDS YP_002737959.1 225856448 7681813 714351..714623 1 NC_012467.1 binds to lower part of 30S body where it stabilizes two domains; required for efficient assembly of 30S; in Escherichia coli this protein has nuclease activity; 30S ribosomal protein S16 714623 rpsP 7681813 rpsP Streptococcus pneumoniae P1031 30S ribosomal protein S16 YP_002737959.1 714351 D 488223 CDS YP_002737960.1 225856449 7681328 714643..714882 1 NC_012467.1 hypothetical protein 714882 7681328 SPP_0784 Streptococcus pneumoniae P1031 hypothetical protein YP_002737960.1 714643 D 488223 CDS YP_002737961.1 225856450 7680884 715459..716247 1 NC_012467.1 identified by match to protein family HMM PF00561; hydrolase, alpha/beta fold family, putative 716247 7680884 SPP_0785 Streptococcus pneumoniae P1031 hydrolase, alpha/beta fold family, putative YP_002737961.1 715459 D 488223 CDS YP_002737962.1 225856451 7680793 716278..716796 1 NC_012467.1 Essential for efficient processing of 16S rRNA; 16S rRNA-processing protein RimM 716796 rimM 7680793 rimM Streptococcus pneumoniae P1031 16S rRNA-processing protein RimM YP_002737962.1 716278 D 488223 CDS YP_002737963.1 225856452 7681469 716786..717505 1 NC_012467.1 methylates guanosine-37 in various tRNAs; uses S-adenosyl-L-methionine to transfer methyl group to tRNA; tRNA (guanine-N(1)-)-methyltransferase 717505 trmD 7681469 trmD Streptococcus pneumoniae P1031 tRNA (guanine-N(1)-)-methyltransferase YP_002737963.1 716786 D 488223 CDS YP_002737964.1 225856453 7680957 717517..717855 1 NC_012467.1 identified by match to protein family HMM PF03477; oxygen-sensitive ribonucleoside-triphosphate reductase 717855 7680957 SPP_0788 Streptococcus pneumoniae P1031 oxygen-sensitive ribonucleoside-triphosphate reductase YP_002737964.1 717517 D 488223 CDS YP_002737965.1 225856454 7682054 complement(717886..718206) 1 NC_012467.1 hypothetical protein 718206 7682054 SPP_0789 Streptococcus pneumoniae P1031 hypothetical protein YP_002737965.1 717886 R 488223 CDS YP_002737966.1 225856455 7680845 718304..718519 1 NC_012467.1 hypothetical protein 718519 7680845 SPP_0791 Streptococcus pneumoniae P1031 hypothetical protein YP_002737966.1 718304 D 488223 CDS YP_002737967.1 225856456 7682300 complement(718516..718662) 1 NC_012467.1 chlorohydrolase 718662 7682300 SPP_0790 Streptococcus pneumoniae P1031 chlorohydrolase YP_002737967.1 718516 R 488223 CDS YP_002737968.1 225856457 7681766 complement(718725..719261) 1 NC_012467.1 identified by match to protein family HMM PF02632; biotin synthase 719261 7681766 SPP_0792 Streptococcus pneumoniae P1031 biotin synthase YP_002737968.1 718725 R 488223 CDS YP_002737969.1 225856458 7680696 complement(719457..720803) 1 NC_012467.1 catalyzes the reduction of 2 glutathione to glutathione disulfide; maintains high levels of reduced glutathione in the cytosol; involved in redox regulation and oxidative defense; glutathione reductase 720803 gor 7680696 gor Streptococcus pneumoniae P1031 glutathione reductase YP_002737969.1 719457 R 488223 CDS YP_002737970.1 225856459 7681198 721068..722267 1 NC_012467.1 identified by match to protein family HMM TIGR01730; membrane-fusion protein 722267 7681198 SPP_0794 Streptococcus pneumoniae P1031 membrane-fusion protein YP_002737970.1 721068 D 488223 CDS YP_002737971.1 225856460 7681017 722251..722952 1 NC_012467.1 identified by match to protein family HMM PF00005; macrolide export ATP-binding/permease protein MacB 722952 7681017 SPP_0795 Streptococcus pneumoniae P1031 macrolide export ATP-binding/permease protein MacB YP_002737971.1 722251 D 488223 CDS YP_002737972.1 225856461 7682072 722954..724213 1 NC_012467.1 identified by match to protein family HMM PF02687; antimicrobial peptide ABC transporter permease 724213 7682072 SPP_0796 Streptococcus pneumoniae P1031 antimicrobial peptide ABC transporter permease YP_002737972.1 722954 D 488223 CDS YP_002737973.1 225856462 7681502 724337..726334 1 NC_012467.1 methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content; methionyl-tRNA synthetase 726334 metG 7681502 metG Streptococcus pneumoniae P1031 methionyl-tRNA synthetase YP_002737973.1 724337 D 488223 CDS YP_002737974.1 225856463 7681699 726755..727075 1 NC_012467.1 identified by match to protein family HMM PF03551; transcriptional regulator, PadR family 727075 7681699 SPP_0798 Streptococcus pneumoniae P1031 transcriptional regulator, PadR family YP_002737974.1 726755 D 488223 CDS YP_002737975.1 225856464 7680907 727079..727894 1 NC_012467.1 hypothetical protein 727894 7680907 SPP_0799 Streptococcus pneumoniae P1031 hypothetical protein YP_002737975.1 727079 D 488223 CDS YP_002737976.1 225856465 7681597 727969..728895 1 NC_012467.1 identified by match to protein family HMM PF00248; oxidoreductase, aldo/keto reductase family protein 728895 7681597 SPP_0800 Streptococcus pneumoniae P1031 oxidoreductase, aldo/keto reductase family protein YP_002737976.1 727969 D 488223 CDS YP_002737977.1 225856466 7682620 728995..729231 1 NC_012467.1 hypothetical protein 729231 7682620 SPP_0801 Streptococcus pneumoniae P1031 hypothetical protein YP_002737977.1 728995 D 488223 CDS YP_002737978.1 225856467 7681233 729224..729922 1 NC_012467.1 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis; 3-ketoacyl-ACP reductase 729922 fabG 7681233 fabG Streptococcus pneumoniae P1031 3-ketoacyl-ACP reductase YP_002737978.1 729224 D 488223 CDS YP_002737979.1 225856468 7681504 729933..730433 1 NC_012467.1 identified by match to protein family HMM PF00293; MutT/nudix family protein 730433 7681504 SPP_0803 Streptococcus pneumoniae P1031 MutT/nudix family protein YP_002737979.1 729933 D 488223 CDS YP_002737980.1 225856469 7681781 730411..731280 1 NC_012467.1 identified by match to protein family HMM PF02896; PEP-utilizing enzyme family protein 731280 7681781 SPP_0804 Streptococcus pneumoniae P1031 PEP-utilizing enzyme family protein YP_002737980.1 730411 D 488223 CDS YP_002737981.1 225856470 7681004 731255..731695 1 NC_012467.1 identified by match to protein family HMM PF06171; hypothetical protein 731695 7681004 SPP_0805 Streptococcus pneumoniae P1031 hypothetical protein YP_002737981.1 731255 D 488223 CDS YP_002737982.1 225856471 7682008 731818..734364 1 NC_012467.1 identified by match to protein family HMM PF01433; aminopeptidase N 734364 7682008 SPP_0806 Streptococcus pneumoniae P1031 aminopeptidase N YP_002737982.1 731818 D 488223 CDS YP_002737983.1 225856472 7681238 734473..735147 1 NC_012467.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00486; transcriptional regulatory protein CiaR 735147 7681238 SPP_0807 Streptococcus pneumoniae P1031 transcriptional regulatory protein CiaR YP_002737983.1 734473 D 488223 CDS YP_002737984.1 225856473 7681287 735137..736471 1 NC_012467.1 identified by match to protein family HMM PF00512; match to protein family HMM PF02518; sensor protein CiaH 736471 7681287 SPP_0808 Streptococcus pneumoniae P1031 sensor protein CiaH YP_002737984.1 735137 D 488223 CDS YP_002737985.1 225856474 7682846 complement(736505..736792) 1 NC_012467.1 hypothetical protein 736792 7682846 SPP_0809 Streptococcus pneumoniae P1031 hypothetical protein YP_002737985.1 736505 R 488223 CDS YP_002737986.1 225856475 7682544 736932..737861 1 NC_012467.1 identified by match to protein family HMM PF01136; protease 737861 7682544 SPP_0810 Streptococcus pneumoniae P1031 protease YP_002737986.1 736932 D 488223 CDS YP_002737987.1 225856476 7681742 738061..740511 1 NC_012467.1 unwinds DNA; bifunctional ATP-dependent DNA helicase/DNA polymerase III subunit epsilon 740511 7681742 SPP_0811 Streptococcus pneumoniae P1031 bifunctional ATP-dependent DNA helicase/DNA polymerase III subunit epsilon YP_002737987.1 738061 D 488223 CDS YP_002737988.1 225856477 7680692 740521..741771 1 NC_012467.1 identified by match to protein family HMM PF01098; RodA 741771 7680692 SPP_0812 Streptococcus pneumoniae P1031 RodA YP_002737988.1 740521 D 488223 CDS YP_002737989.1 225856478 7682069 741782..742336 1 NC_012467.1 identified by match to protein family HMM PF01965; match to protein family HMM TIGR01383; 4-methyl-5(b-hydroxyethyl)-thiazole monophosphate biosynthesis protein 742336 7682069 SPP_0813 Streptococcus pneumoniae P1031 4-methyl-5(b-hydroxyethyl)-thiazole monophosphate biosynthesis protein YP_002737989.1 741782 D 488223 CDS YP_002737990.1 225856479 7680953 742412..742984 1 NC_012467.1 identified by match to protein family HMM PF00702; match to protein family HMM TIGR01549; phosphoglycolate phosphatase 742984 7680953 SPP_0814 Streptococcus pneumoniae P1031 phosphoglycolate phosphatase YP_002737990.1 742412 D 488223 CDS YP_002737991.1 225856480 7682228 742999..744945 1 NC_012467.1 negatively supercoils closed circular double-stranded DNA; DNA gyrase subunit B 744945 gyrB 7682228 gyrB Streptococcus pneumoniae P1031 DNA gyrase subunit B YP_002737991.1 742999 D 488223 CDS YP_002737992.1 225856481 7681131 745027..746754 1 NC_012467.1 acts to negatively regulates ftsZ ring formation by modulating the frequency and position of the ftsZ ring formation; septation ring formation regulator EzrA 746754 ezrA 7681131 ezrA Streptococcus pneumoniae P1031 septation ring formation regulator EzrA YP_002737992.1 745027 D 488223 CDS YP_002737993.1 225856482 7680883 749207..749473 1 NC_012467.1 transposase 749473 7680883 SPP_0819 Streptococcus pneumoniae P1031 transposase YP_002737993.1 749207 D 488223 CDS YP_002737994.1 225856483 7681429 complement(750027..750377) 1 NC_012467.1 identified by match to protein family HMM PF05717; transposase 750377 7681429 SPP_0821 Streptococcus pneumoniae P1031 transposase YP_002737994.1 750027 R 488223 CDS YP_002737995.1 225856484 7681683 751057..751329 1 NC_012467.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; transposase 751329 7681683 SPP_0823 Streptococcus pneumoniae P1031 transposase YP_002737995.1 751057 D 488223 CDS YP_002737996.1 225856485 7682119 751391..751879 1 NC_012467.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by match to protein family HMM PF00665; integrase core domain, putative 751879 7682119 SPP_0824 Streptococcus pneumoniae P1031 integrase core domain, putative YP_002737996.1 751391 D 488223 CDS YP_002737997.1 225856486 7682747 complement(751991..752290) 1 NC_012467.1 identified by match to protein family HMM PF08860; hypothetical protein 752290 7682747 SPP_0825 Streptococcus pneumoniae P1031 hypothetical protein YP_002737997.1 751991 R 488223 CDS YP_002737998.1 225856487 7680873 752988..753317 1 NC_012467.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by match to protein family HMM PF01710; transposase 753317 7680873 SPP_0827 Streptococcus pneumoniae P1031 transposase YP_002737998.1 752988 D 488223 CDS YP_002737999.1 225856488 7680778 complement(754044..756302) 1 NC_012467.1 identified by match to protein family HMM PF00004; match to protein family HMM PF02151; match to protein family HMM PF07724; match to protein family HMM PF07728; negative regulator of genetic competence ClpC/mecB 756302 7680778 SPP_0828 Streptococcus pneumoniae P1031 negative regulator of genetic competence ClpC/mecB YP_002737999.1 754044 R 488223 CDS YP_002738000.1 225856489 7682121 complement(756531..756761) 1 NC_012467.1 identified by match to protein family HMM PF08796; hypothetical protein 756761 7682121 SPP_0829 Streptococcus pneumoniae P1031 hypothetical protein YP_002738000.1 756531 R 488223 CDS YP_002738001.1 225856490 7680677 756951..757634 1 NC_012467.1 identified by match to protein family HMM PF00528; match to protein family HMM TIGR01726; amino acid ABC transporter permease 757634 7680677 SPP_0830 Streptococcus pneumoniae P1031 amino acid ABC transporter permease YP_002738001.1 756951 D 488223 CDS YP_002738002.1 225856491 7681614 757634..758368 1 NC_012467.1 identified by match to protein family HMM PF00005; glutamine transport ATP-binding protein GlnQ 758368 7681614 SPP_0831 Streptococcus pneumoniae P1031 glutamine transport ATP-binding protein GlnQ YP_002738002.1 757634 D 488223 CDS YP_002738003.1 225856492 7681412 758501..759379 1 NC_012467.1 catalyzes the formation of 5,10-methenyltetrahydrofolate from 5,10-methylenetetrahydrofolate and subsequent formation of 10-formyltetrahydrofolate from 5,10-methenyltetrahydrofolate; bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase 759379 7681412 SPP_0832 Streptococcus pneumoniae P1031 bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase YP_002738003.1 758501 D 488223 CDS YP_002738004.1 225856493 7681288 759521..760393 1 NC_012467.1 identified by match to protein family HMM PF01256; match to protein family HMM TIGR00196; putative YjeF homolog, C-terminus 760393 7681288 SPP_0833 Streptococcus pneumoniae P1031 putative YjeF homolog, C-terminus YP_002738004.1 759521 D 488223 CDS YP_002738005.1 225856494 7681767 760675..761358 1 NC_012467.1 Catalyzes D-ribose 5-phosphate --> D-ribulose 5-phosphate in the nonoxidative branch of the pentose phosphate pathway; ribose-5-phosphate isomerase A 761358 rpiA 7681767 rpiA Streptococcus pneumoniae P1031 ribose-5-phosphate isomerase A YP_002738005.1 760675 D 488223 CDS YP_002738006.1 225856495 7682332 761372..762583 1 NC_012467.1 catalyzes the transfer of phosphate between the C1 and C5 carbons of pentose; phosphopentomutase 762583 deoB 7682332 deoB Streptococcus pneumoniae P1031 phosphopentomutase YP_002738006.1 761372 D 488223 CDS YP_002738007.1 225856496 7682439 762585..762995 1 NC_012467.1 identified by match to protein family HMM PF08002; hypothetical protein 762995 7682439 SPP_0836 Streptococcus pneumoniae P1031 hypothetical protein YP_002738007.1 762585 D 488223 CDS YP_002738008.1 225856497 7681204 763143..763952 1 NC_012467.1 catalyzes the formation of a purine and ribose phosphate from a purine nucleoside; in E. coli this enzyme functions in xanthosine degradation; purine nucleoside phosphorylase 763952 7681204 SPP_0837 Streptococcus pneumoniae P1031 purine nucleoside phosphorylase YP_002738008.1 763143 D 488223 CDS YP_002738009.1 225856498 7682543 764428..765159 1 NC_012467.1 hypothetical protein 765159 7682543 SPP_0838 Streptococcus pneumoniae P1031 hypothetical protein YP_002738009.1 764428 D 488223 CDS YP_002738010.1 225856499 7681402 765205..765408 1 NC_012467.1 identified by glimmer; putative; hypothetical protein 765408 7681402 SPP_0839 Streptococcus pneumoniae P1031 hypothetical protein YP_002738010.1 765205 D 488223 CDS YP_002738011.1 225856500 7682756 765433..765945 1 NC_012467.1 hypothetical protein 765945 7682756 SPP_0840 Streptococcus pneumoniae P1031 hypothetical protein YP_002738011.1 765433 D 488223 CDS YP_002738012.1 225856501 7682411 766051..766164 1 NC_012467.1 identified by glimmer; putative; hypothetical protein 766164 7682411 SPP_0841 Streptococcus pneumoniae P1031 hypothetical protein YP_002738012.1 766051 D 488223 CDS YP_002738013.1 225856502 7680663 766603..767313 1 NC_012467.1 catalyzes the reversible phosphorolysis of ribonucleosides and 2'- deoxyribonucleosides to the free base and (2'-deoxy)ribose-1- phosphate; purine nucleoside phosphorylase 767313 deoD 7680663 deoD Streptococcus pneumoniae P1031 purine nucleoside phosphorylase YP_002738013.1 766603 D 488223 CDS YP_002738014.1 225856503 7681165 complement(767336..767860) 1 NC_012467.1 topology modulation protein 767860 7681165 SPP_0843 Streptococcus pneumoniae P1031 topology modulation protein YP_002738014.1 767336 R 488223 CDS YP_002738015.1 225856504 7682221 complement(767913..768149) 1 NC_012467.1 binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase; 30S ribosomal protein S20 768149 rpsT 7682221 rpsT Streptococcus pneumoniae P1031 30S ribosomal protein S20 YP_002738015.1 767913 R 488223 CDS YP_002738016.1 225856505 7682731 complement(768217..769137) 1 NC_012467.1 catalyzes the formation of (R)-4'-phosphopantothenate in coenzyme A biosynthesis; pantothenate kinase 769137 coaA 7682731 coaA Streptococcus pneumoniae P1031 pantothenate kinase YP_002738016.1 768217 R 488223 CDS YP_002738017.1 225856506 7682070 769335..769739 1 NC_012467.1 identified by glimmer; putative; hypothetical protein 769739 7682070 SPP_0846 Streptococcus pneumoniae P1031 hypothetical protein YP_002738017.1 769335 D 488223 CDS YP_002738018.1 225856507 7682393 769955..770536 1 NC_012467.1 identified by match to protein family HMM PF05175; methyltransferase small domain superfamily 770536 7682393 SPP_0847 Streptococcus pneumoniae P1031 methyltransferase small domain superfamily YP_002738018.1 769955 D 488223 CDS YP_002738019.1 225856508 7682414 770533..771810 1 NC_012467.1 Catalyzes the reversible phosphorolysis of pyrimidines in the nucleotide synthesis salvage pathway; pyrimidine-nucleoside phosphorylase 771810 7682414 SPP_0848 Streptococcus pneumoniae P1031 pyrimidine-nucleoside phosphorylase YP_002738019.1 770533 D 488223 CDS YP_002738020.1 225856509 7682624 771828..772490 1 NC_012467.1 catalyzes the formation of D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-D-ribose-5-phosphate; deoxyribose-phosphate aldolase 772490 deoC 7682624 deoC Streptococcus pneumoniae P1031 deoxyribose-phosphate aldolase YP_002738020.1 771828 D 488223 CDS YP_002738021.1 225856510 7681087 772477..772866 1 NC_012467.1 Reclaims exogenous and endogenous cytidine and 2'-deoxycytidine molecules for UMP synthesis; cytidine deaminase 772866 cdd1 7681087 cdd1 Streptococcus pneumoniae P1031 cytidine deaminase YP_002738021.1 772477 D 488223 CDS YP_002738022.1 225856511 7681716 772957..774009 1 NC_012467.1 identified by match to protein family HMM PF02608; lipoprotein 774009 7681716 SPP_0851 Streptococcus pneumoniae P1031 lipoprotein YP_002738022.1 772957 D 488223 CDS YP_002738023.1 225856512 7682345 774153..775688 1 NC_012467.1 identified by match to protein family HMM PF00005; ribose import ATP-binding protein RbsA 775688 7682345 SPP_0852 Streptococcus pneumoniae P1031 ribose import ATP-binding protein RbsA YP_002738023.1 774153 D 488223 CDS YP_002738024.1 225856513 7680947 775681..776739 1 NC_012467.1 identified by match to protein family HMM PF02653; ribose/galactose ABC transporter permease 776739 7680947 SPP_0853 Streptococcus pneumoniae P1031 ribose/galactose ABC transporter permease YP_002738024.1 775681 D 488223 CDS YP_002738025.1 225856514 7681456 776742..777698 1 NC_012467.1 identified by match to protein family HMM PF02653; ribose/galactose ABC transporter permease 777698 7681456 SPP_0854 Streptococcus pneumoniae P1031 ribose/galactose ABC transporter permease YP_002738025.1 776742 D 488223 CDS YP_002738026.1 225856515 7681342 777783..777995 1 NC_012467.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop; transposase 777995 7681342 SPP_0855 Streptococcus pneumoniae P1031 transposase YP_002738026.1 777783 D 488223 CDS YP_002738027.1 225856516 7680882 778131..778280 1 NC_012467.1 identified by glimmer; putative; hypothetical protein 778280 7680882 SPP_0856 Streptococcus pneumoniae P1031 hypothetical protein YP_002738027.1 778131 D 488223 CDS YP_002738028.1 225856517 7682142 778298..778570 1 NC_012467.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; hypothetical protein 778570 7682142 SPP_0857 Streptococcus pneumoniae P1031 hypothetical protein YP_002738028.1 778298 D 488223 CDS YP_002738029.1 225856518 7682226 778632..779120 1 NC_012467.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by match to protein family HMM PF00665; integrase core domain, putative 779120 7682226 SPP_0858 Streptococcus pneumoniae P1031 integrase core domain, putative YP_002738029.1 778632 D 488223 CDS YP_002738030.1 225856519 7680825 complement(779165..779806) 1 NC_012467.1 involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsX; putative glycerol-3-phosphate acyltransferase PlsY 779806 7680825 SPP_0859 Streptococcus pneumoniae P1031 putative glycerol-3-phosphate acyltransferase PlsY YP_002738030.1 779165 R 488223 CDS YP_002738031.1 225856520 7681915 779942..781885 1 NC_012467.1 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling; DNA topoisomerase IV subunit B 781885 parE 7681915 parE Streptococcus pneumoniae P1031 DNA topoisomerase IV subunit B YP_002738031.1 779942 D 488223 CDS YP_002738032.1 225856521 7680992 782006..782131 1 NC_012467.1 identified by glimmer; putative; hypothetical protein 782131 7680992 SPP_0861 Streptococcus pneumoniae P1031 hypothetical protein YP_002738032.1 782006 D 488223 CDS YP_002738033.1 225856522 7682309 782296..784776 1 NC_012467.1 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling; DNA topoisomerase IV subunit A 784776 parC 7682309 parC Streptococcus pneumoniae P1031 DNA topoisomerase IV subunit A YP_002738033.1 782296 D 488223 CDS YP_002738034.1 225856523 7681587 784908..785930 1 NC_012467.1 catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids; branched-chain amino acid aminotransferase 785930 ilvE 7681587 ilvE Streptococcus pneumoniae P1031 branched-chain amino acid aminotransferase YP_002738034.1 784908 D 488223 CDS YP_002738035.1 225856524 7680922 785986..786690 1 NC_012467.1 hypothetical protein 786690 7680922 SPP_0864 Streptococcus pneumoniae P1031 hypothetical protein YP_002738035.1 785986 D 488223 CDS YP_002738036.1 225856525 7681256 786755..787444 1 NC_012467.1 identified by match to protein family HMM PF06149; permease 787444 7681256 SPP_0865 Streptococcus pneumoniae P1031 permease YP_002738036.1 786755 D 488223 CDS YP_002738037.1 225856526 7680649 787441..788364 1 NC_012467.1 identified by match to protein family HMM PF06166; permease 788364 7680649 SPP_0866 Streptococcus pneumoniae P1031 permease YP_002738037.1 787441 D 488223 CDS YP_002738038.1 225856527 7682640 788379..789023 1 NC_012467.1 catalyzes the removal of 5-oxoproline from various penultimate amino acid residues except L-proline; pyrrolidone-carboxylate peptidase 789023 pcp1 7682640 pcp1 Streptococcus pneumoniae P1031 pyrrolidone-carboxylate peptidase YP_002738038.1 788379 D 488223 CDS YP_002738039.1 225856528 7682245 789191..789421 1 NC_012467.1 hypothetical protein 789421 7682245 SPP_0868 Streptococcus pneumoniae P1031 hypothetical protein YP_002738039.1 789191 D 488223 CDS YP_002738040.1 225856529 7680760 789794..790996 1 NC_012467.1 in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins; 30S ribosomal protein S1 790996 rpsA 7680760 rpsA Streptococcus pneumoniae P1031 30S ribosomal protein S1 YP_002738040.1 789794 D 488223 CDS YP_002738041.1 225856530 7681423 791082..791579 1 NC_012467.1 GAF domain-containing protein 791579 7681423 SPP_0872 Streptococcus pneumoniae P1031 GAF domain-containing protein YP_002738041.1 791082 D 488223 CDS YP_002738042.1 225856531 7681578 791579..793234 1 NC_012467.1 catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the tau chain serves as a scaffold to help in the dimerizaton of the alpha,epsilon and theta core complex; the gamma chain seems to interact with the delta and delta' subunits to transfer the beta subunit on the DNA; DNA polymerase III subunits gamma and tau 793234 7681578 SPP_0873 Streptococcus pneumoniae P1031 DNA polymerase III subunits gamma and tau YP_002738042.1 791579 D 488223 CDS YP_002738043.1 225856532 7680630 793286..793456 1 NC_012467.1 hypothetical protein 793456 7680630 SPP_0874 Streptococcus pneumoniae P1031 hypothetical protein YP_002738043.1 793286 D 488223 CDS YP_002738044.1 225856533 7681938 793606..794376 1 NC_012467.1 identified by match to protein family HMM PF00005; match to protein family HMM TIGR01978; FeS assembly ATPase SufC 794376 sufC 7681938 sufC Streptococcus pneumoniae P1031 FeS assembly ATPase SufC YP_002738044.1 793606 D 488223 CDS YP_002738045.1 225856534 7680870 794404..795666 1 NC_012467.1 identified by match to protein family HMM PF01458; match to protein family HMM TIGR01981; FeS assembly protein SufD 795666 sufD 7680870 sufD Streptococcus pneumoniae P1031 FeS assembly protein SufD YP_002738045.1 794404 D 488223 CDS YP_002738046.1 225856535 7680674 795677..796903 1 NC_012467.1 identified by match to protein family HMM PF00266; match to protein family HMM PF01212; match to protein family HMM TIGR01979; cysteine desulfurase (Selenocysteine lyase) (Selenocysteine reductase) (Selenocysteine beta-lyase) (SCL) 796903 7680674 SPP_0877 Streptococcus pneumoniae P1031 cysteine desulfurase (Selenocysteine lyase) (Selenocysteine reductase) (Selenocysteine beta-lyase) (SCL) YP_002738046.1 795677 D 488223 CDS YP_002738047.1 225856536 7682273 796890..797330 1 NC_012467.1 identified by match to protein family HMM PF01592; match to protein family HMM TIGR01994; SUF system FeS assembly protein, NifU family 797330 7682273 SPP_0878 Streptococcus pneumoniae P1031 SUF system FeS assembly protein, NifU family YP_002738047.1 796890 D 488223 CDS YP_002738048.1 225856537 7682058 797384..798796 1 NC_012467.1 identified by match to protein family HMM PF01458; match to protein family HMM TIGR01980; FeS assembly protein SufB 798796 sufB 7682058 sufB Streptococcus pneumoniae P1031 FeS assembly protein SufB YP_002738048.1 797384 D 488223 CDS YP_002738049.1 225856538 7680844 complement(798995..800236) 1 NC_012467.1 identified by match to protein family HMM PF00144; match to protein family HMM PF00768; match to protein family HMM PF07943; D-alanyl-D-alanine carboxypeptidase 800236 7680844 SPP_0880 Streptococcus pneumoniae P1031 D-alanyl-D-alanine carboxypeptidase YP_002738049.1 798995 R 488223 CDS YP_002738050.1 225856539 7681523 800417..801448 1 NC_012467.1 identified by match to protein family HMM PF01594; membrane protein 801448 7681523 SPP_0881 Streptococcus pneumoniae P1031 membrane protein YP_002738050.1 800417 D 488223 CDS YP_002738051.1 225856540 7680725 802873..803613 1 NC_012467.1 identified by match to protein family HMM PF00455; match to protein family HMM PF08220; match to protein family HMM PF08279; transcriptional repressor of the fructose operon 803613 7680725 SPP_0883 Streptococcus pneumoniae P1031 transcriptional repressor of the fructose operon YP_002738051.1 802873 D 488223 CDS YP_002738052.1 225856541 7682196 803610..804521 1 NC_012467.1 identified by match to protein family HMM PF00294; match to protein family HMM TIGR03168; 1-phosphofructokinase 804521 pfkB 7682196 pfkB Streptococcus pneumoniae P1031 1-phosphofructokinase YP_002738052.1 803610 D 488223 CDS YP_002738053.1 225856542 7682845 804518..806470 1 NC_012467.1 identified by match to protein family HMM PF00359; match to protein family HMM PF02378; match to protein family HMM PF02379; match to protein family HMM TIGR00829; match to protein family HMM TIGR00848; match to protein family HMM TIGR01427; PTS system, Fru family, IIABC 806470 7682845 SPP_0885 Streptococcus pneumoniae P1031 PTS system, Fru family, IIABC YP_002738053.1 804518 D 488223 CDS YP_002738054.1 225856543 7682091 806556..808859 1 NC_012467.1 identified by match to protein family HMM PF01580; DNA translocase ftsk 808859 7682091 SPP_0886 Streptococcus pneumoniae P1031 DNA translocase ftsk YP_002738054.1 806556 D 488223 CDS YP_002738055.1 225856544 7681308 complement(809012..809440) 1 NC_012467.1 hypothetical protein 809440 7681308 SPP_0887 Streptococcus pneumoniae P1031 hypothetical protein YP_002738055.1 809012 R 488223 CDS YP_002738056.1 225856545 7681941 809578..810720 1 NC_012467.1 identified by match to protein family HMM PF00266; cysteine desulfurase 810720 7681941 SPP_0888 Streptococcus pneumoniae P1031 cysteine desulfurase YP_002738056.1 809578 D 488223 CDS YP_002738057.1 225856546 7682039 810729..811943 1 NC_012467.1 Required for the synthesis of the thiazole moiety; thiamine biosynthesis protein ThiI 811943 thiI 7682039 thiI Streptococcus pneumoniae P1031 thiamine biosynthesis protein ThiI YP_002738057.1 810729 D 488223 CDS YP_002738058.1 225856547 7682755 812078..812902 1 NC_012467.1 identified by match to protein family HMM PF00756; putative esterase superfamily 812902 7682755 SPP_0890 Streptococcus pneumoniae P1031 putative esterase superfamily YP_002738058.1 812078 D 488223 CDS YP_002738059.1 225856548 7681876 812915..814081 1 NC_012467.1 carbamoylphosphate synthase large subunit 814081 7681876 SPP_0891 Streptococcus pneumoniae P1031 carbamoylphosphate synthase large subunit YP_002738059.1 812915 D 488223 CDS YP_002738060.1 225856549 7682812 814341..814466 1 NC_012467.1 identified by glimmer; putative; hypothetical protein 814466 7682812 SPP_0892 Streptococcus pneumoniae P1031 hypothetical protein YP_002738060.1 814341 D 488223 CDS YP_002738061.1 225856550 7682600 814589..816082 1 NC_012467.1 identified by match to protein family HMM PF02384; type I restriction modification enzyme methylase subunit 816082 7682600 SPP_0893 Streptococcus pneumoniae P1031 type I restriction modification enzyme methylase subunit YP_002738061.1 814589 D 488223 CDS YP_002738062.1 225856551 7681132 816095..817216 1 NC_012467.1 identified by match to protein family HMM PF01420; type I restriction-modification system, S subunit, putative 817216 7681132 SPP_0894 Streptococcus pneumoniae P1031 type I restriction-modification system, S subunit, putative YP_002738062.1 816095 D 488223 CDS YP_002738063.1 225856552 7682174 817276..817512 1 NC_012467.1 hypothetical protein 817512 7682174 SPP_0895 Streptococcus pneumoniae P1031 hypothetical protein YP_002738063.1 817276 D 488223 CDS YP_002738064.1 225856553 7682340 817509..817922 1 NC_012467.1 identified by match to protein family HMM PF05012; match to protein family HMM TIGR01550; prophage maintenance system killer protein 817922 7682340 SPP_0896 Streptococcus pneumoniae P1031 prophage maintenance system killer protein YP_002738064.1 817509 D 488223 CDS YP_002738065.1 225856554 7682036 818040..819005 1 NC_012467.1 identified by match to protein family HMM PF00589; match to protein family HMM PF02899; integrase/recombinase, phage integrase family 819005 7682036 SPP_0897 Streptococcus pneumoniae P1031 integrase/recombinase, phage integrase family YP_002738065.1 818040 D 488223 CDS YP_002738066.1 225856555 7681299 818971..819609 1 NC_012467.1 identified by match to protein family HMM PF01420; type I restriction-modification enzyme S subunit 819609 7681299 SPP_0898 Streptococcus pneumoniae P1031 type I restriction-modification enzyme S subunit YP_002738066.1 818971 D 488223 CDS YP_002738067.1 225856556 7681785 819639..822989 1 NC_012467.1 identified by match to protein family HMM PF00270; match to protein family HMM PF00271; match to protein family HMM PF04313; match to protein family HMM PF04851; type I restriction-modification system R subunit 822989 7681785 SPP_0899 Streptococcus pneumoniae P1031 type I restriction-modification system R subunit YP_002738067.1 819639 D 488223 CDS YP_002738068.1 225856557 7680643 823260..823460 1 NC_012467.1 chlorohydrolase 823460 7680643 SPP_0900 Streptococcus pneumoniae P1031 chlorohydrolase YP_002738068.1 823260 D 488223 CDS YP_002738069.1 225856558 7682074 complement(823575..824045) 1 NC_012467.1 identified by match to protein family HMM PF01316; match to protein family HMM PF02863; arginine repressor 824045 7682074 SPP_0901 Streptococcus pneumoniae P1031 arginine repressor YP_002738069.1 823575 R 488223 CDS YP_002738070.1 225856559 7682169 complement(824062..826335) 1 NC_012467.1 catalyzes the removal of N-terminal dipeptides when proline is the penultimate residue; x-prolyl-dipeptidyl aminopeptidase 826335 7682169 SPP_0902 Streptococcus pneumoniae P1031 x-prolyl-dipeptidyl aminopeptidase YP_002738070.1 824062 R 488223 CDS YP_002738071.1 225856560 7681082 826681..829782 1 NC_012467.1 Catalyzes DNA-template-directed extension of the 3'-end of a DNA strand by one nucleotide at a time. Proposed to be responsible for the synthesis of the lagging strand. In the low GC gram positive bacteria this enzyme is less processive and more error prone than its counterpart in other bacteria.; DNA polymerase III DnaE 829782 dnaE 7681082 dnaE Streptococcus pneumoniae P1031 DNA polymerase III DnaE YP_002738071.1 826681 D 488223 CDS YP_002738072.1 225856561 7680698 829865..830872 1 NC_012467.1 catalyzes the formation of D-fructose 1,6-bisphosphate from D-fructose 6-phosphate in glycolysis; 6-phosphofructokinase 830872 pfkA 7680698 pfkA Streptococcus pneumoniae P1031 6-phosphofructokinase YP_002738072.1 829865 D 488223 CDS YP_002738073.1 225856562 7682804 830931..832436 1 NC_012467.1 catalyzes the formation of phosphoenolpyruvate from pyruvate; pyruvate kinase 832436 pyk 7682804 pyk Streptococcus pneumoniae P1031 pyruvate kinase YP_002738073.1 830931 D 488223 CDS YP_002738074.1 225856563 7681725 834187..835059 1 NC_012467.1 lipoprotein, putative 835059 7681725 SPP_0907 Streptococcus pneumoniae P1031 lipoprotein, putative YP_002738074.1 834187 D 488223 CDS YP_002738075.1 225856564 7682684 complement(835166..835366) 1 NC_012467.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop; mobile genetic element 835366 7682684 SPP_0908 Streptococcus pneumoniae P1031 mobile genetic element YP_002738075.1 835166 R 488223 CDS YP_002738076.1 225856565 7682333 complement(835367..835549) 1 NC_012467.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop; mobile genetic element 835549 7682333 SPP_0909 Streptococcus pneumoniae P1031 mobile genetic element YP_002738076.1 835367 R 488223 CDS YP_002738077.1 225856566 7682744 835692..835973 1 NC_012467.1 identified by glimmer; putative; hypothetical protein 835973 7682744 SPP_0910 Streptococcus pneumoniae P1031 hypothetical protein YP_002738077.1 835692 D 488223 CDS YP_002738078.1 225856567 7682321 836008..836724 1 NC_012467.1 hypothetical protein 836724 7682321 SPP_0911 Streptococcus pneumoniae P1031 hypothetical protein YP_002738078.1 836008 D 488223 CDS YP_002738079.1 225856568 7681883 complement(836854..837669) 1 NC_012467.1 identified by match to protein family HMM PF09323; ABC transporter substrate-binding protein 837669 7681883 SPP_0912 Streptococcus pneumoniae P1031 ABC transporter substrate-binding protein YP_002738079.1 836854 R 488223 CDS YP_002738080.1 225856569 7682370 complement(837666..838571) 1 NC_012467.1 identified by match to protein family HMM PF03773; membrane protein 838571 7682370 SPP_0913 Streptococcus pneumoniae P1031 membrane protein YP_002738080.1 837666 R 488223 CDS YP_002738081.1 225856570 7681395 complement(838572..838703) 1 NC_012467.1 identified by glimmer; putative; hypothetical protein 838703 7681395 SPP_0914 Streptococcus pneumoniae P1031 hypothetical protein YP_002738081.1 838572 R 488223 CDS YP_002738082.1 225856571 7681790 839028..841157 1 NC_012467.1 identified by match to protein family HMM PF00575; S1 RNA binding domain protein 841157 7681790 SPP_0915 Streptococcus pneumoniae P1031 S1 RNA binding domain protein YP_002738082.1 839028 D 488223 CDS YP_002738083.1 225856572 7681494 841099..841593 1 NC_012467.1 identified by match to protein family HMM PF03926; hypothetical protein 841593 7681494 SPP_0916 Streptococcus pneumoniae P1031 hypothetical protein YP_002738083.1 841099 D 488223 CDS YP_002738084.1 225856573 7681161 841652..841924 1 NC_012467.1 identified by match to protein family HMM PF04024; PspC domain family 841924 7681161 SPP_0917 Streptococcus pneumoniae P1031 PspC domain family YP_002738084.1 841652 D 488223 CDS YP_002738085.1 225856574 7682823 842897..843655 1 NC_012467.1 identified by match to protein family HMM PF00005; bacitracin export ATP-binding protein BceA 843655 7682823 SPP_0918 Streptococcus pneumoniae P1031 bacitracin export ATP-binding protein BceA YP_002738085.1 842897 D 488223 CDS YP_002738086.1 225856575 7681302 843657..845645 1 NC_012467.1 identified by match to protein family HMM PF02687; antimicrobial peptide ABC transporter permease 845645 7681302 SPP_0919 Streptococcus pneumoniae P1031 antimicrobial peptide ABC transporter permease YP_002738086.1 843657 D 488223 CDS YP_002738087.1 225856576 7682847 complement(845687..846277) 1 NC_012467.1 identified by match to protein family HMM PF01988; integral membrane protein 846277 7682847 SPP_0920 Streptococcus pneumoniae P1031 integral membrane protein YP_002738087.1 845687 R 488223 CDS YP_002738088.1 225856577 7681908 complement(846303..847352) 1 NC_012467.1 identified by match to protein family HMM PF00665; transposase 847352 7681908 SPP_0921 Streptococcus pneumoniae P1031 transposase YP_002738088.1 846303 R 488223 CDS YP_002738089.1 225856578 7681409 complement(847585..847698) 1 NC_012467.1 hypothetical protein 847698 7681409 SPP_0922 Streptococcus pneumoniae P1031 hypothetical protein YP_002738089.1 847585 R 488223 CDS YP_002738090.1 225856579 7682581 848059..849534 1 NC_012467.1 identified by match to protein family HMM PF00266; match to protein family HMM PF01212; match to protein family HMM PF01276; match to protein family HMM PF03711; arginine decarboxylase 849534 7682581 SPP_0924 Streptococcus pneumoniae P1031 arginine decarboxylase YP_002738090.1 848059 D 488223 CDS YP_002738091.1 225856580 7681382 complement(849500..849736) 1 NC_012467.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; hypothetical protein 849736 7681382 SPP_0923 Streptococcus pneumoniae P1031 hypothetical protein YP_002738091.1 849500 R 488223 CDS YP_002738092.1 225856581 7682385 complement(849688..850215) 1 NC_012467.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; transposase 850215 7682385 SPP_0925 Streptococcus pneumoniae P1031 transposase YP_002738092.1 849688 R 488223 CDS YP_002738093.1 225856582 7682550 850471..851331 1 NC_012467.1 catalyzes the formation of spermidine from putrescine and S-adenosylmethioninamine; spermidine synthase 851331 speE 7682550 speE Streptococcus pneumoniae P1031 spermidine synthase YP_002738093.1 850471 D 488223 CDS YP_002738094.1 225856583 7681176 851328..852587 1 NC_012467.1 identified by match to protein family HMM PF03435; saccharopine dehydrogenase 852587 lys 7681176 lys Streptococcus pneumoniae P1031 saccharopine dehydrogenase YP_002738094.1 851328 D 488223 CDS YP_002738095.1 225856584 7681844 852587..853714 1 NC_012467.1 identified by match to protein family HMM PF00278; match to protein family HMM TIGR01047; carboxynorspermidine decarboxylase 853714 nspC 7681844 nspC Streptococcus pneumoniae P1031 carboxynorspermidine decarboxylase YP_002738095.1 852587 D 488223 CDS YP_002738096.1 225856585 7682830 853711..854796 1 NC_012467.1 catalyzes the formation of carbamoylputrescine from agmatine in the arginine decarboxylase pathway of putrescine biosynthesis; agmatine deiminase 854796 aguA 7682830 aguA Streptococcus pneumoniae P1031 agmatine deiminase YP_002738096.1 853711 D 488223 CDS YP_002738097.1 225856586 7682592 854806..855681 1 NC_012467.1 identified by match to protein family HMM PF00795; match to protein family HMM TIGR03381; N-carbamoylputrescine amidase 855681 aguB 7682592 aguB Streptococcus pneumoniae P1031 N-carbamoylputrescine amidase YP_002738097.1 854806 D 488223 CDS YP_002738098.1 225856587 7682825 complement(855862..856671) 1 NC_012467.1 identified by match to protein family HMM PF00702; match to protein family HMM PF05116; match to protein family HMM PF08282; match to protein family HMM TIGR00099; match to protein family HMM TIGR01484; Cof family protein 856671 7682825 SPP_0931 Streptococcus pneumoniae P1031 Cof family protein YP_002738098.1 855862 R 488223 CDS YP_002738099.1 225856588 7680864 857218..857889 1 NC_012467.1 identified by match to protein family HMM PF02517; caax amino protease family 857889 7680864 SPP_0932 Streptococcus pneumoniae P1031 caax amino protease family YP_002738099.1 857218 D 488223 CDS YP_002738100.1 225856589 7682334 complement(857941..858138) 1 NC_012467.1 hypothetical protein 858138 7682334 SPP_0933 Streptococcus pneumoniae P1031 hypothetical protein YP_002738100.1 857941 R 488223 CDS YP_002738101.1 225856590 7681285 858131..859039 1 NC_012467.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466; regulatory function on capsule expression in group B streptococci 859039 7681285 SPP_0934 Streptococcus pneumoniae P1031 regulatory function on capsule expression in group B streptococci YP_002738101.1 858131 D 488223 CDS YP_002738102.1 225856591 7681135 859036..859497 1 NC_012467.1 lipoprotein signal peptidase; integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis; lipoprotein signal peptidase 859497 lspA 7681135 lspA Streptococcus pneumoniae P1031 lipoprotein signal peptidase YP_002738102.1 859036 D 488223 CDS YP_002738103.1 225856592 7682406 859487..860374 1 NC_012467.1 identified by match to protein family HMM PF00849; match to protein family HMM PF01479; match to protein family HMM TIGR00005; ribosomal large subunit pseudouridine synthase D (rRNA-uridine isomerase D) (rRNA pseudouridylate synthase D) 860374 7682406 SPP_0936 Streptococcus pneumoniae P1031 ribosomal large subunit pseudouridine synthase D (rRNA-uridine isomerase D) (rRNA pseudouridylate synthase D) YP_002738103.1 859487 D 488223 CDS YP_002738104.1 225856593 7682325 860377..862260 1 NC_012467.1 identified by match to protein family HMM PF00753; match to protein family HMM PF01473; choline binding protein E 862260 7682325 SPP_0937 Streptococcus pneumoniae P1031 choline binding protein E YP_002738104.1 860377 D 488223 CDS YP_002738105.1 225856594 7681676 862361..863470 1 NC_012467.1 catalyzes the formation of glutamate 5-phosphate from glutamate in proline biosynthesis; gamma-glutamyl kinase 863470 proB 7681676 proB Streptococcus pneumoniae P1031 gamma-glutamyl kinase YP_002738105.1 862361 D 488223 CDS YP_002738106.1 225856595 7682110 863480..864742 1 NC_012467.1 Catalyzes the phosphorylation of L-glutamate during the proline biosynthesis pathway; gamma-glutamyl phosphate reductase 864742 proA 7682110 proA Streptococcus pneumoniae P1031 gamma-glutamyl phosphate reductase YP_002738106.1 863480 D 488223 CDS YP_002738107.1 225856596 7682124 864746..865543 1 NC_012467.1 identified by match to protein family HMM PF01210; match to protein family HMM PF03446; match to protein family HMM PF03807; match to protein family HMM TIGR00112; pyrroline-5-carboxylate reductase 865543 proC 7682124 proC Streptococcus pneumoniae P1031 pyrroline-5-carboxylate reductase YP_002738107.1 864746 D 488223 CDS YP_002738108.1 225856597 7682347 865763..866401 1 NC_012467.1 catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to thymidine monophosphate (dTMP) to form thymidine diphosphate (dTDP); thymidylate kinase 866401 tmk 7682347 tmk Streptococcus pneumoniae P1031 thymidylate kinase YP_002738108.1 865763 D 488223 CDS YP_002738109.1 225856598 7681770 866398..867288 1 NC_012467.1 catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the delta' subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA.; DNA polymerase III subunit delta' 867288 7681770 SPP_0942 Streptococcus pneumoniae P1031 DNA polymerase III subunit delta' YP_002738109.1 866398 D 488223 CDS YP_002738110.1 225856599 7681224 867328..867645 1 NC_012467.1 in Bacillus subtilis this protein is involved in the negative regulation of DNA replication initiation; interacts with DnaN and DnaA; DNA replication intiation control protein YabA 867645 7681224 SPP_0943 Streptococcus pneumoniae P1031 DNA replication intiation control protein YabA YP_002738110.1 867328 D 488223 CDS YP_002738111.1 225856600 7681732 867648..868517 1 NC_012467.1 identified by match to protein family HMM PF00590; match to protein family HMM TIGR00096; hypothetical protein 868517 7681732 SPP_0944 Streptococcus pneumoniae P1031 hypothetical protein YP_002738111.1 867648 D 488223 CDS YP_002738112.1 225856601 7682774 868744..869262 1 NC_012467.1 identified by match to protein family HMM PF08020; hypothetical protein 869262 7682774 SPP_0945 Streptococcus pneumoniae P1031 hypothetical protein YP_002738112.1 868744 D 488223 CDS YP_002738113.1 225856602 7681605 869371..870018 1 NC_012467.1 identified by match to protein family HMM PF06970; phage protein 870018 7681605 SPP_0947 Streptococcus pneumoniae P1031 phage protein YP_002738113.1 869371 D 488223 CDS YP_002738114.1 225856603 7682118 complement(870007..870396) 1 NC_012467.1 identified by match to protein family HMM PF01609; transposase (IS4 family) 870396 7682118 SPP_0946 Streptococcus pneumoniae P1031 transposase (IS4 family) YP_002738114.1 870007 R 488223 CDS YP_002738115.1 225856604 7682733 871454..872788 1 NC_012467.1 TrmFO; Gid; glucose-inhibited division protein; similar to GidA; the gene from Bacillus subtilis encodes a tRNA-methyltransferase that utilizes folate as the carbon donor and bound flavin as reductant; modifies tRNA at position 54 (uridine) of the T-psi loop to form a C5-methyluridine; tRNA (uracil-5-)-methyltransferase Gid 872788 trmFO 7682733 trmFO Streptococcus pneumoniae P1031 tRNA (uracil-5-)-methyltransferase Gid YP_002738115.1 871454 D 488223 CDS YP_002738116.1 225856605 7682462 872872..873609 1 NC_012467.1 Catalyzes the phosphorylation of UMP to UDP; uridylate kinase 873609 pyrH 7682462 pyrH Streptococcus pneumoniae P1031 uridylate kinase YP_002738116.1 872872 D 488223 CDS YP_002738117.1 225856606 7681206 873618..874175 1 NC_012467.1 Rrf; Frr; ribosome-recycling factor; release factor 4; RF4; recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G; A GTPase-dependent process results in release of 50S from 70S; inhibited by release factor RF-1; essential for viability; structurally similar to tRNAs; ribosome recycling factor 874175 frr 7681206 frr Streptococcus pneumoniae P1031 ribosome recycling factor YP_002738117.1 873618 D 488223 CDS YP_002738118.1 225856607 7682173 874196..875089 1 NC_012467.1 s1 RNA binding domain protein 875089 7682173 SPP_0953 Streptococcus pneumoniae P1031 s1 RNA binding domain protein YP_002738118.1 874196 D 488223 CDS YP_002738119.1 225856608 7681905 875098..875313 1 NC_012467.1 identified by match to protein family HMM PF06855; hypothetical protein 875313 7681905 SPP_0954 Streptococcus pneumoniae P1031 hypothetical protein YP_002738119.1 875098 D 488223 CDS YP_002738120.1 225856609 7681034 875399..876367 1 NC_012467.1 identified by match to protein family HMM PF02562; PhoH family protein 876367 7681034 SPP_0955 Streptococcus pneumoniae P1031 PhoH family protein YP_002738120.1 875399 D 488223 CDS YP_002738121.1 225856610 7681846 876547..877047 1 NC_012467.1 identified by match to protein family HMM PF00583; acetyltransferase, gnat family 877047 7681846 SPP_0956 Streptococcus pneumoniae P1031 acetyltransferase, gnat family YP_002738121.1 876547 D 488223 CDS YP_002738122.1 225856611 7682800 877050..877277 1 NC_012467.1 identified by glimmer; putative; hypothetical protein 877277 7682800 SPP_0957 Streptococcus pneumoniae P1031 hypothetical protein YP_002738122.1 877050 D 488223 CDS YP_002738123.1 225856612 7682097 878965..879534 1 NC_012467.1 identified by match to protein family HMM PF00583; acetyltransferase, gnat family 879534 7682097 SPP_0960 Streptococcus pneumoniae P1031 acetyltransferase, gnat family YP_002738123.1 878965 D 488223 CDS YP_002738124.1 225856613 7681400 879602..880252 1 NC_012467.1 identified by match to protein family HMM PF00633; match to protein family HMM TIGR00426; match to protein family HMM TIGR01259; competence protein CelA 880252 7681400 SPP_0961 Streptococcus pneumoniae P1031 competence protein CelA YP_002738124.1 879602 D 488223 CDS YP_002738125.1 225856614 7681860 880236..882476 1 NC_012467.1 identified by match to protein family HMM PF03772; match to protein family HMM TIGR00360; match to protein family HMM TIGR00361; DNA internalization-related competence protein ComEC/Rec2 882476 7681860 SPP_0962 Streptococcus pneumoniae P1031 DNA internalization-related competence protein ComEC/Rec2 YP_002738125.1 880236 D 488223 CDS YP_002738126.1 225856615 7681893 882876..883463 1 NC_012467.1 identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 883463 7681893 SPP_0963 Streptococcus pneumoniae P1031 ABC transporter ATP-binding protein YP_002738126.1 882876 D 488223 CDS YP_002738127.1 225856616 7680908 883467..884651 1 NC_012467.1 hypothetical protein 884651 7680908 SPP_0964 Streptococcus pneumoniae P1031 hypothetical protein YP_002738127.1 883467 D 488223 CDS YP_002738128.1 225856617 7680993 884937..885494 1 NC_012467.1 IF-3 has several functions that are required and promote translation initiation including; preventing association of 70S by binding to 30S; monitoring codon-anticodon interactions by promoting disassociation of fMet-tRNA(fMet) from initiation complexes formed on leaderless mRNAs or incorrectly bound noninitiatior tRNAs and complexes with noncanonical start sites; stimulates codon-anticodon interactions at P-site; involved in moving mRNA to the P-site; and in recycling subunits; translation initiation factor IF-3 885494 infC 7680993 infC Streptococcus pneumoniae P1031 translation initiation factor IF-3 YP_002738128.1 884937 D 488223 CDS YP_002738129.1 225856618 7681977 885527..885727 1 NC_012467.1 identified by match to protein family HMM PF01632; match to protein family HMM TIGR00001; 50S ribosomal protein L35 885727 rpmI 7681977 rpmI Streptococcus pneumoniae P1031 50S ribosomal protein L35 YP_002738129.1 885527 D 488223 CDS YP_002738130.1 225856619 7682466 885779..886138 1 NC_012467.1 binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit; 50S ribosomal protein L20 886138 rplT 7682466 rplT Streptococcus pneumoniae P1031 50S ribosomal protein L20 YP_002738130.1 885779 D 488223 CDS YP_002738131.1 225856620 7681241 886196..886576 1 NC_012467.1 identified by match to protein family HMM PF00903; lactoylglutathione lyase 886576 7681241 SPP_0968 Streptococcus pneumoniae P1031 lactoylglutathione lyase YP_002738131.1 886196 D 488223 CDS YP_002738132.1 225856621 7681272 886826..887626 1 NC_012467.1 responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the pyrD subunit to the ultimate electron acceptor NAD(+); dihydroorotate dehydrogenase electron transfer subunit 887626 7681272 SPP_0969 Streptococcus pneumoniae P1031 dihydroorotate dehydrogenase electron transfer subunit YP_002738132.1 886826 D 488223 CDS YP_002738133.1 225856622 7681544 887637..888575 1 NC_012467.1 catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway, using a flavin nucleotide as an essential cofactor; subclass 1B is a heterotetramer consisting of two PyrDB subunits, similar to the PyrDA subunits and two PyrK subunits; dihydroorotate dehydrogenase 1B 888575 7681544 SPP_0970 Streptococcus pneumoniae P1031 dihydroorotate dehydrogenase 1B YP_002738133.1 887637 D 488223 CDS YP_002738134.1 225856623 7681420 888674..890782 1 NC_012467.1 identified by match to protein family HMM PF01473; match to protein family HMM PF01832; endo-beta-N-acetylglucosaminidase 890782 7681420 SPP_0971 Streptococcus pneumoniae P1031 endo-beta-N-acetylglucosaminidase YP_002738134.1 888674 D 488223 CDS YP_002738135.1 225856624 7681967 complement(890843..892498) 1 NC_012467.1 identified by match to protein family HMM PF05670; match to protein family HMM PF05833; fibronectin/fibrinogen binding protein 892498 7681967 SPP_0972 Streptococcus pneumoniae P1031 fibronectin/fibrinogen binding protein YP_002738135.1 890843 R 488223 CDS YP_002738136.1 225856625 7681430 892603..893100 1 NC_012467.1 identified by match to protein family HMM PF02130; match to protein family HMM TIGR00043; putative metalloprotease 893100 7681430 SPP_0973 Streptococcus pneumoniae P1031 putative metalloprotease YP_002738136.1 892603 D 488223 CDS YP_002738137.1 225856626 7680944 893081..893476 1 NC_012467.1 identified by match to protein family HMM PF01219; diacylglycerol kinase (dagk) (diglyceride kinase)(dgk) 893476 7680944 SPP_0974 Streptococcus pneumoniae P1031 diacylglycerol kinase (dagk) (diglyceride kinase)(dgk) YP_002738137.1 893081 D 488223 CDS YP_002738138.1 225856627 7680860 893493..894392 1 NC_012467.1 Era; Escherichia coli Ras-like protein; Bex; Bacillus Era-complementing segment; essential protein in Escherichia coli that is involved in many cellular processes; GTPase; binds the cell membrane through apparent C-terminal domain; mutants are arrested during the cell cycle; Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome; GTP-binding protein Era 894392 era 7680860 era Streptococcus pneumoniae P1031 GTP-binding protein Era YP_002738138.1 893493 D 488223 CDS YP_002738139.1 225856628 7682832 894441..895265 1 NC_012467.1 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases; formamidopyrimidine-DNA glycosylase 895265 mutM 7682832 mutM Streptococcus pneumoniae P1031 formamidopyrimidine-DNA glycosylase YP_002738139.1 894441 D 488223 CDS YP_002738140.1 225856629 7681817 895265..895870 1 NC_012467.1 catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; involved in coenzyme A biosynthesis; dephospho-CoA kinase 895870 coaE 7681817 coaE Streptococcus pneumoniae P1031 dephospho-CoA kinase YP_002738140.1 895265 D 488223 CDS YP_002738141.1 225856630 7681517 895857..897056 1 NC_012467.1 identified by match to protein family HMM PF07690; multidrug resistance protein MdtG 897056 7681517 SPP_0978 Streptococcus pneumoniae P1031 multidrug resistance protein MdtG YP_002738141.1 895857 D 488223 CDS YP_002738142.1 225856631 7681451 897056..897205 1 NC_012467.1 in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif; 50S ribosomal protein L33 897205 rpmG 7681451 rpmG Streptococcus pneumoniae P1031 50S ribosomal protein L33 YP_002738142.1 897056 D 488223 CDS YP_002738143.1 225856632 7680667 897245..897478 1 NC_012467.1 identified by match to protein family HMM PF03840; match to protein family HMM TIGR00810; preprotein translocase subunit SecG 897478 secG 7680667 secG Streptococcus pneumoniae P1031 preprotein translocase subunit SecG YP_002738143.1 897245 D 488223 CDS YP_002738144.1 225856633 7682559 897580..899934 1 NC_012467.1 identified by match to protein family HMM PF00575; match to protein family HMM PF00773; match to protein family HMM PF08206; match to protein family HMM TIGR00358; match to protein family HMM TIGR02063; ribonuclease R 899934 rnr 7682559 rnr Streptococcus pneumoniae P1031 ribonuclease R YP_002738144.1 897580 D 488223 CDS YP_002738145.1 225856634 7681214 899897..900364 1 NC_012467.1 binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation; SsrA-binding protein 900364 smpB 7681214 smpB Streptococcus pneumoniae P1031 SsrA-binding protein YP_002738145.1 899897 D 488223 CDS YP_002738146.1 225856635 7680660 900380..901240 1 NC_012467.1 with TehA confers resistance to tellurite; tellurite resistance protein TehB 901240 tehB 7680660 tehB Streptococcus pneumoniae P1031 tellurite resistance protein TehB YP_002738146.1 900380 D 488223 CDS YP_002738147.1 225856636 7681992 901313..902266 1 NC_012467.1 identified by match to protein family HMM PF06054; competence protein 902266 7681992 SPP_0984 Streptococcus pneumoniae P1031 competence protein YP_002738147.1 901313 D 488223 CDS YP_002738148.1 225856637 7682175 902285..904087 1 NC_012467.1 identified by match to protein family HMM PF01432; match to protein family HMM PF08439; match to protein family HMM TIGR00181; oligoendopeptidase F 904087 pepF1 7682175 pepF1 Streptococcus pneumoniae P1031 oligoendopeptidase F YP_002738148.1 902285 D 488223 CDS YP_002738149.1 225856638 7682305 904125..904802 1 NC_012467.1 identified by match to protein family HMM PF01596; match to protein family HMM PF08241; O-methyltransferase family protein 904802 7682305 SPP_0986 Streptococcus pneumoniae P1031 O-methyltransferase family protein YP_002738149.1 904125 D 488223 CDS YP_002738150.1 225856639 7682237 904869..905810 1 NC_012467.1 cis/trans isomerase of peptidylprolyl; PPIase; membrane-bound lipoprotein; foldase protein PrsA 905810 prsA 7682237 prsA Streptococcus pneumoniae P1031 foldase protein PrsA YP_002738150.1 904869 D 488223 CDS YP_002738151.1 225856640 7682244 complement(905927..906268) 1 NC_012467.1 transposase, IS3 family 906268 7682244 SPP_0988 Streptococcus pneumoniae P1031 transposase, IS3 family YP_002738151.1 905927 R 488223 CDS YP_002738152.1 225856641 7682661 complement(906268..906459) 1 NC_012467.1 transposase 906459 7682661 SPP_0989 Streptococcus pneumoniae P1031 transposase YP_002738152.1 906268 R 488223 CDS YP_002738153.1 225856642 7680826 complement(907029..907649) 1 NC_012467.1 identified by match to protein family HMM PF00300; phosphoglycerate mutase 907649 7680826 SPP_0990 Streptococcus pneumoniae P1031 phosphoglycerate mutase YP_002738153.1 907029 R 488223 CDS YP_002738154.1 225856643 7680931 complement(907649..908131) 1 NC_012467.1 identified by match to protein family HMM PF04073; regulatory protein 908131 7680931 SPP_0991 Streptococcus pneumoniae P1031 regulatory protein YP_002738154.1 907649 R 488223 CDS YP_002738155.1 225856644 7680990 complement(908131..908973) 1 NC_012467.1 identified by match to protein family HMM PF04018; integral membrane protein 908973 7680990 SPP_0992 Streptococcus pneumoniae P1031 integral membrane protein YP_002738155.1 908131 R 488223 CDS YP_002738156.1 225856645 7681104 complement(909068..909868) 1 NC_012467.1 identified by match to protein family HMM PF01183; lyzozyme M1 909868 7681104 SPP_0993 Streptococcus pneumoniae P1031 lyzozyme M1 YP_002738156.1 909068 R 488223 CDS YP_002738157.1 225856646 7681088 909964..911391 1 NC_012467.1 forms a homotrimer; catalyzes the acetylation of glucosamine-1-phosphate and uridylation of N-acetylglucosamine-1-phosphate to produce UDP-GlcNAc; function in cell wall synthesis; bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase 911391 glmU 7681088 glmU Streptococcus pneumoniae P1031 bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase YP_002738157.1 909964 D 488223 CDS YP_002738158.1 225856647 7682458 911401..911946 1 NC_012467.1 identified by match to protein family HMM PF00293; ADP-ribose pyrophosphatase 911946 7682458 SPP_0995 Streptococcus pneumoniae P1031 ADP-ribose pyrophosphatase YP_002738158.1 911401 D 488223 CDS YP_002738159.1 225856648 7682356 911958..912272 1 NC_012467.1 hypothetical protein 912272 7682356 SPP_0996 Streptococcus pneumoniae P1031 hypothetical protein YP_002738159.1 911958 D 488223 CDS YP_002738160.1 225856649 7681723 912289..912981 1 NC_012467.1 enables the cleavage of the glycosidic bond in both 5'-methylthioadenosine and S-adenosylhomocysteine; 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase 912981 mtnN 7681723 mtnN Streptococcus pneumoniae P1031 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase YP_002738160.1 912289 D 488223 CDS YP_002738161.1 225856650 7682655 913058..913549 1 NC_012467.1 identified by match to protein family HMM PF04394; hypothetical protein 913549 7682655 SPP_0998 Streptococcus pneumoniae P1031 hypothetical protein YP_002738161.1 913058 D 488223 CDS YP_002738162.1 225856651 7680646 913623..914213 1 NC_012467.1 3'-5' exonuclease of DNA polymerase III; DNA polymerase III subunit epsilon 914213 7680646 SPP_0999 Streptococcus pneumoniae P1031 DNA polymerase III subunit epsilon YP_002738162.1 913623 D 488223 CDS YP_002738163.1 225856652 7681633 914222..915985 1 NC_012467.1 identified by match to protein family HMM PF03009; glycerophosphoryl diester phosphodiesterase family protein 915985 7681633 SPP_1000 Streptococcus pneumoniae P1031 glycerophosphoryl diester phosphodiesterase family protein YP_002738163.1 914222 D 488223 CDS YP_002738164.1 225856653 7681063 916199..916528 1 NC_012467.1 identified by match to protein family HMM PF01710; transposase 916528 7681063 SPP_1001 Streptococcus pneumoniae P1031 transposase YP_002738164.1 916199 D 488223 CDS YP_002738165.1 225856654 7681857 916707..916847 1 NC_012467.1 hypothetical protein 916847 7681857 SPP_1002 Streptococcus pneumoniae P1031 hypothetical protein YP_002738165.1 916707 D 488223 CDS YP_002738166.1 225856655 7682354 917008..917208 1 NC_012467.1 hypothetical protein 917208 7682354 SPP_1003 Streptococcus pneumoniae P1031 hypothetical protein YP_002738166.1 917008 D 488223 CDS YP_002738167.1 225856656 7682103 917250..917654 1 NC_012467.1 hypothetical protein 917654 7682103 SPP_1004 Streptococcus pneumoniae P1031 hypothetical protein YP_002738167.1 917250 D 488223 CDS YP_002738168.1 225856657 7681514 917885..918592 1 NC_012467.1 identified by match to protein family HMM PF02683; cytochrome c-type biogenesis protein CcdA 918592 7681514 SPP_1005 Streptococcus pneumoniae P1031 cytochrome c-type biogenesis protein CcdA YP_002738168.1 917885 D 488223 CDS YP_002738169.1 225856658 7682420 918603..919160 1 NC_012467.1 identified by match to protein family HMM PF00578; match to protein family HMM PF08534; thioredoxin family protein 919160 7682420 SPP_1006 Streptococcus pneumoniae P1031 thioredoxin family protein YP_002738169.1 918603 D 488223 CDS YP_002738170.1 225856659 7682784 919535..920926 1 NC_012467.1 identified by match to protein family HMM PF00324; amino acid permease family protein 920926 7682784 SPP_1007 Streptococcus pneumoniae P1031 amino acid permease family protein YP_002738170.1 919535 D 488223 CDS YP_002738171.1 225856660 7681393 921069..921986 1 NC_012467.1 identified by match to protein family HMM PF01297; zinc-binding lipoprotein AdcA 921986 7681393 SPP_1008 Streptococcus pneumoniae P1031 zinc-binding lipoprotein AdcA YP_002738171.1 921069 D 488223 CDS YP_002738172.1 225856661 7681232 921994..924525 1 NC_012467.1 identified by match to protein family HMM PF04270; match to protein family HMM TIGR01363; pneumococcal histidine triad protein B 924525 7681232 SPP_1009 Streptococcus pneumoniae P1031 pneumococcal histidine triad protein B YP_002738172.1 921994 D 488223 CDS YP_002738173.1 225856662 7680976 924736..927855 1 NC_012467.1 identified by match to protein family HMM PF04270; match to protein family HMM TIGR01363; pneumococcal histidine triad protein B 927855 7680976 SPP_1010 Streptococcus pneumoniae P1031 pneumococcal histidine triad protein B YP_002738173.1 924736 D 488223 CDS YP_002738174.1 225856663 7682418 928685..929254 1 NC_012467.1 identified by match to protein family HMM PF04270; pneumococcal histidine triad protein E 929254 7682418 SPP_1011 Streptococcus pneumoniae P1031 pneumococcal histidine triad protein E YP_002738174.1 928685 D 488223 CDS YP_002738175.1 225856664 7681309 929549..930106 1 NC_012467.1 hypothetical protein 930106 7681309 SPP_1012 Streptococcus pneumoniae P1031 hypothetical protein YP_002738175.1 929549 D 488223 CDS YP_002738176.1 225856665 7680914 complement(930142..931365) 1 NC_012467.1 catalyzes the release of the N-terminal amino acid from a tripeptide; peptidase T 931365 pepT 7680914 pepT Streptococcus pneumoniae P1031 peptidase T YP_002738176.1 930142 R 488223 CDS YP_002738177.1 225856666 7682831 complement(932535..932912) 1 NC_012467.1 identified by match to protein family HMM PF01741; match to protein family HMM TIGR00220; large conductance mechanosensitive channel protein 932912 mscL 7682831 mscL Streptococcus pneumoniae P1031 large conductance mechanosensitive channel protein YP_002738177.1 932535 R 488223 CDS YP_002738178.1 225856667 7681477 complement(932994..933425) 1 NC_012467.1 identified by match to protein family HMM PF04138; MesH protein 933425 7681477 SPP_1017 Streptococcus pneumoniae P1031 MesH protein YP_002738178.1 932994 R 488223 CDS YP_002738179.1 225856668 7682538 933548..934057 1 NC_012467.1 identified by match to protein family HMM PF06177; citrulline cluster-linked protein 934057 7682538 SPP_1018 Streptococcus pneumoniae P1031 citrulline cluster-linked protein YP_002738179.1 933548 D 488223 CDS YP_002738180.1 225856669 7680723 934571..935647 1 NC_012467.1 catalyzes the formation of 4-aspartyl phosphate from aspartate 4-semialdehyde; aspartate-semialdehyde dehydrogenase 935647 asd 7680723 asd Streptococcus pneumoniae P1031 aspartate-semialdehyde dehydrogenase YP_002738180.1 934571 D 488223 CDS YP_002738181.1 225856670 7681311 935703..936638 1 NC_012467.1 catalyzes the formation of dihydrodipicolinate from L-aspartate 4-semialdehyde and pyruvate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate synthase 936638 dapA 7681311 dapA Streptococcus pneumoniae P1031 dihydrodipicolinate synthase YP_002738181.1 935703 D 488223 CDS YP_002738182.1 225856671 7682536 complement(936685..938058) 1 NC_012467.1 in Escherichia coli this protein is involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2-thiouridine, which is found in the wobble position of some tRNAs and affects ribosomal frameshifting; shows potassium-dependent dimerization and GTP hydrolysis; also involved in regulation of glutamate-dependent acid resistance and activation of gadE; tRNA modification GTPase TrmE 938058 trmE 7682536 trmE Streptococcus pneumoniae P1031 tRNA modification GTPase TrmE YP_002738182.1 936685 R 488223 CDS YP_002738183.1 225856672 7681629 complement(938195..938377) 1 NC_012467.1 4-OT; member of subfamily 5; forms a dimer; the function in the Escherichia coli cell is unknown; 4-oxalocrotonate tautomerase 938377 7681629 SPP_1023 Streptococcus pneumoniae P1031 4-oxalocrotonate tautomerase YP_002738183.1 938195 R 488223 CDS YP_002738184.1 225856673 7680975 938500..939099 1 NC_012467.1 catalyzes the formation of thymidine 5'-phosphate from thymidine; thymidine kinase 939099 tdk 7680975 tdk Streptococcus pneumoniae P1031 thymidine kinase YP_002738184.1 938500 D 488223 CDS YP_002738185.1 225856674 7681585 939089..939568 1 NC_012467.1 identified by match to protein family HMM PF00583; acetyltransferase, gnat family 939568 7681585 SPP_1025 Streptococcus pneumoniae P1031 acetyltransferase, gnat family YP_002738185.1 939089 D 488223 CDS YP_002738186.1 225856675 7681078 939578..940657 1 NC_012467.1 recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2; peptide chain release factor 1 940657 prfA 7681078 prfA Streptococcus pneumoniae P1031 peptide chain release factor 1 YP_002738186.1 939578 D 488223 CDS YP_002738187.1 225856676 7682437 940657..941496 1 NC_012467.1 identified by match to protein family HMM PF05175; match to protein family HMM PF08241; match to protein family HMM PF08242; match to protein family HMM TIGR00536; match to protein family HMM TIGR03387; protein-(glutamine-N5) methyltransferase, release factor-specific 941496 hemK 7682437 hemK Streptococcus pneumoniae P1031 protein-(glutamine-N5) methyltransferase, release factor-specific YP_002738187.1 940657 D 488223 CDS YP_002738188.1 225856677 7682448 941480..942082 1 NC_012467.1 identified by match to protein family HMM PF01300; match to protein family HMM TIGR00057; Sua5/YciO/YrdC/YwlC family protein 942082 7682448 SPP_1028 Streptococcus pneumoniae P1031 Sua5/YciO/YrdC/YwlC family protein YP_002738188.1 941480 D 488223 CDS YP_002738189.1 225856678 7681978 942084..942515 1 NC_012467.1 identified by match to protein family HMM PF00583; acetyltransferase, gnat family protein 942515 7681978 SPP_1029 Streptococcus pneumoniae P1031 acetyltransferase, gnat family protein YP_002738189.1 942084 D 488223 CDS YP_002738190.1 225856679 7681277 942577..943833 1 NC_012467.1 catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate; serine hydroxymethyltransferase 943833 glyA 7681277 glyA Streptococcus pneumoniae P1031 serine hydroxymethyltransferase YP_002738190.1 942577 D 488223 CDS YP_002738191.1 225856680 7682088 943841..944815 1 NC_012467.1 hypothetical protein 944815 7682088 SPP_1031 Streptococcus pneumoniae P1031 hypothetical protein YP_002738191.1 943841 D 488223 CDS YP_002738192.1 225856681 7680645 944815..945429 1 NC_012467.1 pneumococcal vaccine antigen A 945429 7680645 SPP_1032 Streptococcus pneumoniae P1031 pneumococcal vaccine antigen A YP_002738192.1 944815 D 488223 CDS YP_002738193.1 225856682 7682279 945503..946477 1 NC_012467.1 identified by match to protein family HMM PF06207; hypothetical protein 946477 7682279 SPP_1033 Streptococcus pneumoniae P1031 hypothetical protein YP_002738193.1 945503 D 488223 CDS YP_002738194.1 225856683 7681271 946551..948182 1 NC_012467.1 identified by match to protein family HMM PF01938; match to protein family HMM PF05958; match to protein family HMM TIGR00479; 23S rRNA (uracil-5-)-methyltransferase RumA 948182 rumA1 7681271 rumA1 Streptococcus pneumoniae P1031 23S rRNA (uracil-5-)-methyltransferase RumA YP_002738194.1 946551 D 488223 CDS YP_002738195.1 225856684 7682760 948920..949138 1 NC_012467.1 hypothetical protein 949138 7682760 SPP_1035 Streptococcus pneumoniae P1031 hypothetical protein YP_002738195.1 948920 D 488223 CDS YP_002738196.1 225856685 7681101 949531..950556 1 NC_012467.1 identified by match to protein family HMM PF01497; ABC transporter substrate-binding protein - iron transport 950556 7681101 SPP_1036 Streptococcus pneumoniae P1031 ABC transporter substrate-binding protein - iron transport YP_002738196.1 949531 D 488223 CDS YP_002738197.1 225856686 7681444 950546..951553 1 NC_012467.1 identified by match to protein family HMM PF01032; iron-compound ABC transporter, permease protein 951553 7681444 SPP_1037 Streptococcus pneumoniae P1031 iron-compound ABC transporter, permease protein YP_002738197.1 950546 D 488223 CDS YP_002738198.1 225856687 7682352 951553..952560 1 NC_012467.1 identified by match to protein family HMM PF01032; Fe3+ ABC transporter permease 952560 7682352 SPP_1038 Streptococcus pneumoniae P1031 Fe3+ ABC transporter permease YP_002738198.1 951553 D 488223 CDS YP_002738199.1 225856688 7681753 952560..953354 1 NC_012467.1 identified by match to protein family HMM PF00005; ferric enterobactin transport ATP-binding protein FepC 953354 7681753 SPP_1039 Streptococcus pneumoniae P1031 ferric enterobactin transport ATP-binding protein FepC YP_002738199.1 952560 D 488223 CDS YP_002738200.1 225856689 7681380 954280..954411 1 NC_012467.1 hypothetical protein 954411 7681380 SPP_1040 Streptococcus pneumoniae P1031 hypothetical protein YP_002738200.1 954280 D 488223 CDS YP_002738201.1 225856690 7681511 955095..955256 1 NC_012467.1 hypothetical protein 955256 7681511 SPP_1041 Streptococcus pneumoniae P1031 hypothetical protein YP_002738201.1 955095 D 488223 CDS YP_002738202.1 225856691 7681337 957295..957861 1 NC_012467.1 hypothetical protein 957861 7681337 SPP_1044 Streptococcus pneumoniae P1031 hypothetical protein YP_002738202.1 957295 D 488223 CDS YP_002738203.1 225856692 7681903 958184..958372 1 NC_012467.1 hypothetical protein 958372 7681903 SPP_1045 Streptococcus pneumoniae P1031 hypothetical protein YP_002738203.1 958184 D 488223 CDS YP_002738204.1 225856693 7680919 958434..959192 1 NC_012467.1 identified by glimmer; putative; hypothetical protein 959192 7680919 SPP_1046 Streptococcus pneumoniae P1031 hypothetical protein YP_002738204.1 958434 D 488223 CDS YP_002738205.1 225856694 7682290 959250..960104 1 NC_012467.1 identified by match to protein family HMM PF03747; ADP-ribosylation/Crystallin J1 960104 7682290 SPP_1047 Streptococcus pneumoniae P1031 ADP-ribosylation/Crystallin J1 YP_002738205.1 959250 D 488223 CDS YP_002738206.1 225856695 7682683 960216..961100 1 NC_012467.1 identified by match to protein family HMM PF00781; match to protein family HMM TIGR00147; hypothetical protein 961100 7682683 SPP_1048 Streptococcus pneumoniae P1031 hypothetical protein YP_002738206.1 960216 D 488223 CDS YP_002738207.1 225856696 7682183 963275..963730 1 NC_012467.1 identified by glimmer; putative; hypothetical protein 963730 7682183 SPP_1051 Streptococcus pneumoniae P1031 hypothetical protein YP_002738207.1 963275 D 488223 CDS YP_002738208.1 225856697 7681651 963870..963983 1 NC_012467.1 hypothetical protein 963983 7681651 SPP_1052 Streptococcus pneumoniae P1031 hypothetical protein YP_002738208.1 963870 D 488223 CDS YP_002738209.1 225856698 7681800 964173..964649 1 NC_012467.1 identified by match to protein family HMM PF01381; helix-turn-helix domain protein 964649 7681800 SPP_1053 Streptococcus pneumoniae P1031 helix-turn-helix domain protein YP_002738209.1 964173 D 488223 CDS YP_002738210.1 225856699 7681231 964649..965410 1 NC_012467.1 identified by match to protein family HMM PF06414; signal recognition particle GTPase 965410 7681231 SPP_1054 Streptococcus pneumoniae P1031 signal recognition particle GTPase YP_002738210.1 964649 D 488223 CDS YP_002738211.1 225856700 7681940 965438..966595 1 NC_012467.1 hypothetical protein 966595 7681940 SPP_1055 Streptococcus pneumoniae P1031 hypothetical protein YP_002738211.1 965438 D 488223 CDS YP_002738212.1 225856701 7682441 967414..967773 1 NC_012467.1 hypothetical protein 967773 7682441 SPP_1056 Streptococcus pneumoniae P1031 hypothetical protein YP_002738212.1 967414 D 488223 CDS YP_002738213.1 225856702 7681081 971152..972021 1 NC_012467.1 identified by match to protein family HMM PF03446; NAD binding domain of 6-phosphogluconate dehydrogenase family 972021 7681081 SPP_1062 Streptococcus pneumoniae P1031 NAD binding domain of 6-phosphogluconate dehydrogenase family YP_002738213.1 971152 D 488223 CDS YP_002738214.1 225856703 7681782 972008..972730 1 NC_012467.1 identified by glimmer; putative; hypothetical protein 972730 7681782 SPP_1063 Streptococcus pneumoniae P1031 hypothetical protein YP_002738214.1 972008 D 488223 CDS YP_002738215.1 225856704 7682745 972727..973257 1 NC_012467.1 hypothetical protein 973257 7682745 SPP_1064 Streptococcus pneumoniae P1031 hypothetical protein YP_002738215.1 972727 D 488223 CDS YP_002738216.1 225856705 7682611 973261..974355 1 NC_012467.1 identified by glimmer; putative; hypothetical protein 974355 7682611 SPP_1065 Streptococcus pneumoniae P1031 hypothetical protein YP_002738216.1 973261 D 488223 CDS YP_002738217.1 225856706 7682850 974358..975029 1 NC_012467.1 identified by glimmer; putative; hypothetical protein 975029 7682850 SPP_1066 Streptococcus pneumoniae P1031 hypothetical protein YP_002738217.1 974358 D 488223 CDS YP_002738218.1 225856707 7682507 975031..976059 1 NC_012467.1 identified by match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF02719; match to protein family HMM PF07993; match to protein family HMM TIGR01179; UDP-glucose 4-epimerase 976059 galE1 7682507 galE1 Streptococcus pneumoniae P1031 UDP-glucose 4-epimerase YP_002738218.1 975031 D 488223 CDS YP_002738219.1 225856708 7681373 976083..977327 1 NC_012467.1 biotin carboxylase 977327 7681373 SPP_1068 Streptococcus pneumoniae P1031 biotin carboxylase YP_002738219.1 976083 D 488223 CDS YP_002738220.1 225856709 7682685 979220..979441 1 NC_012467.1 identified by match to protein family HMM PF01381; hypothetical protein 979441 7682685 SPP_1071 Streptococcus pneumoniae P1031 hypothetical protein YP_002738220.1 979220 D 488223 CDS YP_002738221.1 225856710 7681290 979889..980083 1 NC_012467.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop; mobile genetic element 980083 7681290 SPP_1072 Streptococcus pneumoniae P1031 mobile genetic element YP_002738221.1 979889 D 488223 CDS YP_002738222.1 225856711 7681179 980347..981576 1 NC_012467.1 identified by match to protein family HMM PF01098; cell division protein FtsW 981576 7681179 SPP_1073 Streptococcus pneumoniae P1031 cell division protein FtsW YP_002738222.1 980347 D 488223 CDS YP_002738223.1 225856712 7681834 981596..984292 1 NC_012467.1 catalyzes the formation of oxaloacetate from phosphoenolpyruvate; phosphoenolpyruvate carboxylase 984292 ppc 7681834 ppc Streptococcus pneumoniae P1031 phosphoenolpyruvate carboxylase YP_002738223.1 981596 D 488223 CDS YP_002738224.1 225856713 7681223 984705..985709 1 NC_012467.1 identified by match to protein family HMM PF04392; ABC transporter substrate-binding protein 985709 7681223 SPP_1075 Streptococcus pneumoniae P1031 ABC transporter substrate-binding protein YP_002738224.1 984705 D 488223 CDS YP_002738225.1 225856714 7682549 985778..986644 1 NC_012467.1 identified by match to protein family HMM PF02653; ABC transporter 986644 7682549 SPP_1076 Streptococcus pneumoniae P1031 ABC transporter YP_002738225.1 985778 D 488223 CDS YP_002738226.1 225856715 7682727 986641..987399 1 NC_012467.1 identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 987399 7682727 SPP_1077 Streptococcus pneumoniae P1031 ABC transporter ATP-binding protein YP_002738226.1 986641 D 488223 CDS YP_002738227.1 225856716 7681190 987489..989249 1 NC_012467.1 synthesizes RNA primers at the replication forks; DNA primase 989249 dnaG 7681190 dnaG Streptococcus pneumoniae P1031 DNA primase YP_002738227.1 987489 D 488223 CDS YP_002738228.1 225856717 7680672 989252..990361 1 NC_012467.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; primary sigma factor of bacterium; RNA polymerase sigma factor RpoD 990361 7680672 SPP_1079 Streptococcus pneumoniae P1031 RNA polymerase sigma factor RpoD YP_002738228.1 989252 D 488223 CDS YP_002738229.1 225856718 7682269 990375..990704 1 NC_012467.1 identified by match to protein family HMM PF01883; N-6 Adenine-specific DNA methylase YitW 990704 7682269 SPP_1080 Streptococcus pneumoniae P1031 N-6 Adenine-specific DNA methylase YitW YP_002738229.1 990375 D 488223 CDS YP_002738230.1 225856719 7680849 990819..991862 1 NC_012467.1 identified by match to protein family HMM PF00534; glycosyl transferase CpoA 991862 7680849 SPP_1081 Streptococcus pneumoniae P1031 glycosyl transferase CpoA YP_002738230.1 990819 D 488223 CDS YP_002738231.1 225856720 7682065 991878..993203 1 NC_012467.1 identified by match to protein family HMM PF00534; glycosyl transferase, group 1 993203 7682065 SPP_1082 Streptococcus pneumoniae P1031 glycosyl transferase, group 1 YP_002738231.1 991878 D 488223 CDS YP_002738232.1 225856721 7681016 993234..993410 1 NC_012467.1 identified by match to protein family HMM PF04024; hypothetical protein 993410 7681016 SPP_1083 Streptococcus pneumoniae P1031 hypothetical protein YP_002738232.1 993234 D 488223 CDS YP_002738233.1 225856722 7680926 993469..993603 1 NC_012467.1 hypothetical protein 993603 7680926 SPP_1084 Streptococcus pneumoniae P1031 hypothetical protein YP_002738233.1 993469 D 488223 CDS YP_002738234.1 225856723 7680966 993673..994977 1 NC_012467.1 essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication; GTPase ObgE 994977 obgE 7680966 obgE Streptococcus pneumoniae P1031 GTPase ObgE YP_002738234.1 993673 D 488223 CDS YP_002738235.1 225856724 7682303 994987..995145 1 NC_012467.1 hypothetical protein 995145 7682303 SPP_1086 Streptococcus pneumoniae P1031 hypothetical protein YP_002738235.1 994987 D 488223 CDS YP_002738236.1 225856725 7680796 996195..997454 1 NC_012467.1 adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active; UDP-N-acetylglucosamine 1-carboxyvinyltransferase 997454 murA1 7680796 murA1 Streptococcus pneumoniae P1031 UDP-N-acetylglucosamine 1-carboxyvinyltransferase YP_002738236.1 996195 D 488223 CDS YP_002738237.1 225856726 7680659 997470..998021 1 NC_012467.1 identified by match to protein family HMM PF00583; acetyltransferase, gnat family protein 998021 7680659 SPP_1088 Streptococcus pneumoniae P1031 acetyltransferase, gnat family protein YP_002738237.1 997470 D 488223 CDS YP_002738238.1 225856727 7682248 998014..999291 1 NC_012467.1 identified by match to protein family HMM PF00571; match to protein family HMM PF07085; match to protein family HMM PF08279; cytosolic protein containing multiple CBS domains 999291 7682248 SPP_1089 Streptococcus pneumoniae P1031 cytosolic protein containing multiple CBS domains YP_002738238.1 998014 D 488223 CDS YP_002738239.1 225856728 7682553 999307..1000167 1 NC_012467.1 catalyzes the removal of N-terminal amino acids from peptides and arylamides; methionine aminopeptidase 1000167 map 7682553 map Streptococcus pneumoniae P1031 methionine aminopeptidase YP_002738239.1 999307 D 488223 CDS YP_002738240.1 225856729 7681168 1000547..1000966 1 NC_012467.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; mobile genetic element 1000966 7681168 SPP_1091 Streptococcus pneumoniae P1031 mobile genetic element YP_002738240.1 1000547 D 488223 CDS YP_002738241.1 225856730 7680776 1000963..1001352 1 NC_012467.1 identified by match to protein family HMM PF01609; transposase (IS4 family) 1001352 7680776 SPP_1092 Streptococcus pneumoniae P1031 transposase (IS4 family) YP_002738241.1 1000963 D 488223 CDS YP_002738242.1 225856731 7681263 1001543..1003834 1 NC_012467.1 identified by match to protein family HMM PF00580; match to protein family HMM TIGR01073; ATP-dependent DNA helicase PcrA 1003834 pcrA 7681263 pcrA Streptococcus pneumoniae P1031 ATP-dependent DNA helicase PcrA YP_002738242.1 1001543 D 488223 CDS YP_002738243.1 225856732 7682400 1003877..1004557 1 NC_012467.1 Involved in DNA double-strand break repair and recombination. Promotes the annealing of complementary single-stranded DNA and by simulation of RAD51 recombinase; DNA repair protein RadC 1004557 radC 7682400 radC Streptococcus pneumoniae P1031 DNA repair protein RadC YP_002738243.1 1003877 D 488223 CDS YP_002738244.1 225856733 7681892 complement(1004554..1005243) 1 NC_012467.1 identified by match to protein family HMM PF00117; match to protein family HMM PF07722; glutamine amidotransferase, class I 1005243 7681892 SPP_1094 Streptococcus pneumoniae P1031 glutamine amidotransferase, class I YP_002738244.1 1004554 R 488223 CDS YP_002738245.1 225856734 7681033 complement(1005261..1005902) 1 NC_012467.1 modulates transcription in response to the NADH/NAD(+) redox state; redox-sensing transcriptional repressor Rex 1005902 7681033 SPP_1096 Streptococcus pneumoniae P1031 redox-sensing transcriptional repressor Rex YP_002738245.1 1005261 R 488223 CDS YP_002738246.1 225856735 7682765 complement(1005985..1006200) 1 NC_012467.1 hypothetical protein 1006200 7682765 SPP_1097 Streptococcus pneumoniae P1031 hypothetical protein YP_002738246.1 1005985 R 488223 CDS YP_002738247.1 225856736 7681280 complement(1006208..1006555) 1 NC_012467.1 identified by match to protein family HMM PF08866; hypothetical protein 1006555 7681280 SPP_1098 Streptococcus pneumoniae P1031 hypothetical protein YP_002738247.1 1006208 R 488223 CDS YP_002738248.1 225856737 7680850 complement(1006560..1007675) 1 NC_012467.1 identified by match to protein family HMM PF00266; cysteine desulfurase 1007675 7680850 SPP_1099 Streptococcus pneumoniae P1031 cysteine desulfurase YP_002738248.1 1006560 R 488223 CDS YP_002738249.1 225856738 7681127 complement(1007685..1008644) 1 NC_012467.1 catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP; ribose-phosphate pyrophosphokinase 1008644 7681127 SPP_1100 Streptococcus pneumoniae P1031 ribose-phosphate pyrophosphokinase YP_002738249.1 1007685 R 488223 CDS YP_002738250.1 225856739 7681411 complement(1008757..1009326) 1 NC_012467.1 identified by match to protein family HMM PF01928; adenylate cyclase 1009326 7681411 SPP_1101 Streptococcus pneumoniae P1031 adenylate cyclase YP_002738250.1 1008757 R 488223 CDS YP_002738251.1 225856740 7681581 1009454..1010125 1 NC_012467.1 identified by match to protein family HMM PF04607; GTP pyrophosphokinase 1010125 7681581 SPP_1102 Streptococcus pneumoniae P1031 GTP pyrophosphokinase YP_002738251.1 1009454 D 488223 CDS YP_002738252.1 225856741 7680633 1010109..1010927 1 NC_012467.1 catalyzes the phosphorylation of NAD to NADP; inorganic polyphosphate/ATP-NAD kinase 1010927 ppnK 7680633 ppnK Streptococcus pneumoniae P1031 inorganic polyphosphate/ATP-NAD kinase YP_002738252.1 1010109 D 488223 CDS YP_002738253.1 225856742 7681512 1010924..1011820 1 NC_012467.1 identified by match to protein family HMM PF00849; match to protein family HMM TIGR00005; ribosomal large subunit pseudouridine synthase, RluD subfamily 1011820 7681512 SPP_1104 Streptococcus pneumoniae P1031 ribosomal large subunit pseudouridine synthase, RluD subfamily YP_002738253.1 1010924 D 488223 CDS YP_002738254.1 225856743 7682446 1011864..1012838 1 NC_012467.1 in Salmonella this enzyme is required for ethanolamine catabolism; has higher affinity for CoA than Pta; phosphotransacetylase 1012838 eutD 7682446 eutD Streptococcus pneumoniae P1031 phosphotransacetylase YP_002738254.1 1011864 D 488223 CDS YP_002738255.1 225856744 7681463 complement(1014450..1014749) 1 NC_012467.1 identified by match to protein family HMM PF02575; match to protein family HMM TIGR00103; hypothetical protein 1014749 7681463 SPP_1108 Streptococcus pneumoniae P1031 hypothetical protein YP_002738255.1 1014450 R 488223 CDS YP_002738256.1 225856745 7682179 1016036..1016350 1 NC_012467.1 identified by match to protein family HMM PF00829; match to protein family HMM TIGR00061; 50S ribosomal protein L21 1016350 rplU 7682179 rplU Streptococcus pneumoniae P1031 50S ribosomal protein L21 YP_002738256.1 1016036 D 488223 CDS YP_002738257.1 225856746 7681111 1016366..1016710 1 NC_012467.1 identified by match to protein family HMM PF04327; hypothetical protein 1016710 7681111 SPP_1111 Streptococcus pneumoniae P1031 hypothetical protein YP_002738257.1 1016366 D 488223 CDS YP_002738258.1 225856747 7681601 1016727..1017020 1 NC_012467.1 involved in the peptidyltransferase reaction during translation; 50S ribosomal protein L27 1017020 rpmA 7681601 rpmA Streptococcus pneumoniae P1031 50S ribosomal protein L27 YP_002738258.1 1016727 D 488223 CDS YP_002738259.1 225856748 7681714 complement(1017366..1017536) 1 NC_012467.1 identified by glimmer; putative; hypothetical protein 1017536 7681714 SPP_1113 Streptococcus pneumoniae P1031 hypothetical protein YP_002738259.1 1017366 R 488223 CDS YP_002738260.1 225856749 7680881 complement(1017508..1017636) 1 NC_012467.1 hypothetical protein 1017636 7680881 SPP_1114 Streptococcus pneumoniae P1031 hypothetical protein YP_002738260.1 1017508 R 488223 CDS YP_002738261.1 225856750 7681039 1017973..1018890 1 NC_012467.1 catalyzes the formation of FMN from riboflavin and the formation of FAD from FMN; in Bacillus the ribC gene has both flavokinase and FAD synthetase activities; bifunctional riboflavin kinase/FMN adenylyltransferase 1018890 ribF 7681039 ribF Streptococcus pneumoniae P1031 bifunctional riboflavin kinase/FMN adenylyltransferase YP_002738261.1 1017973 D 488223 CDS YP_002738262.1 225856751 7682033 complement(1018983..1019831) 1 NC_012467.1 identified by match to protein family HMM PF02588; hypothetical protein 1019831 7682033 SPP_1116 Streptococcus pneumoniae P1031 hypothetical protein YP_002738262.1 1018983 R 488223 CDS YP_002738263.1 225856752 7681958 1019973..1020812 1 NC_012467.1 identified by match to protein family HMM PF02645; match to protein family HMM TIGR00762; hypothetical protein 1020812 7681958 SPP_1117 Streptococcus pneumoniae P1031 hypothetical protein YP_002738263.1 1019973 D 488223 CDS YP_002738264.1 225856753 7682489 1020919..1021194 1 NC_012467.1 identified by match to protein family HMM PF00216; DNA-binding protein HU 1 (DNA-binding protein II) (HB) 1021194 7682489 SPP_1118 Streptococcus pneumoniae P1031 DNA-binding protein HU 1 (DNA-binding protein II) (HB) YP_002738264.1 1020919 D 488223 CDS YP_002738265.1 225856754 7682613 1021621..1023522 1 NC_012467.1 identified by match to protein family HMM PF00005; ATPase component of ABC transporter with duplicated ATPase domains 1023522 7682613 SPP_1119 Streptococcus pneumoniae P1031 ATPase component of ABC transporter with duplicated ATPase domains YP_002738265.1 1021621 D 488223 CDS YP_002738266.1 225856755 7682835 1023525..1024388 1 NC_012467.1 identified by match to protein family HMM TIGR01716; transcriptional regulator 1024388 7682835 SPP_1120 Streptococcus pneumoniae P1031 transcriptional regulator YP_002738266.1 1023525 D 488223 CDS YP_002738267.1 225856756 7681108 1024468..1025646 1 NC_012467.1 identified by match to protein family HMM PF07690; macrolide ABC transporter permease 1025646 7681108 SPP_1121 Streptococcus pneumoniae P1031 macrolide ABC transporter permease YP_002738267.1 1024468 D 488223 CDS YP_002738268.1 225856757 7682167 1025739..1027697 1 NC_012467.1 this protein catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction; essential for DNA replication and repair of damaged DNA; similar to ligase LigB; NAD-dependent DNA ligase LigA 1027697 ligA 7682167 ligA Streptococcus pneumoniae P1031 NAD-dependent DNA ligase LigA YP_002738268.1 1025739 D 488223 CDS YP_002738269.1 225856758 7681365 1027809..1030088 1 NC_012467.1 identified by match to protein family HMM PF00128; match to protein family HMM PF02922; match to protein family HMM TIGR02104; pullulanase, type I 1030088 pulA 7681365 pulA Streptococcus pneumoniae P1031 pullulanase, type I YP_002738269.1 1027809 D 488223 CDS YP_002738270.1 225856759 7681009 complement(1030440..1030613) 1 NC_012467.1 hypothetical protein 1030613 7681009 SPP_1124 Streptococcus pneumoniae P1031 hypothetical protein YP_002738270.1 1030440 R 488223 CDS YP_002738271.1 225856760 7682837 1030632..1032056 1 NC_012467.1 identified by match to protein family HMM PF00171; NADP-dependent glyceraldehyde-3-phosphate dehydrogenase 1032056 7682837 SPP_1125 Streptococcus pneumoniae P1031 NADP-dependent glyceraldehyde-3-phosphate dehydrogenase YP_002738271.1 1030632 D 488223 CDS YP_002738272.1 225856761 7682598 1032539..1034467 1 NC_012467.1 catalyzes the transfer of a segment of a 1,4-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain; glycogen branching enzyme 1034467 glgB 7682598 glgB Streptococcus pneumoniae P1031 glycogen branching enzyme YP_002738272.1 1032539 D 488223 CDS YP_002738273.1 225856762 7681334 1034457..1035599 1 NC_012467.1 catalyzes the formation of ADP-glucose and diphosphate from ATP and alpha-D-glucose 1-phosphate; glucose-1-phosphate adenylyltransferase 1035599 glgC 7681334 glgC Streptococcus pneumoniae P1031 glucose-1-phosphate adenylyltransferase YP_002738273.1 1034457 D 488223 CDS YP_002738274.1 225856763 7680877 1035589..1036728 1 NC_012467.1 identified by match to protein family HMM PF00483; match to protein family HMM TIGR02092; glucose-1-phosphate adenylyltransferase, GlgD subunit 1036728 glgD 7680877 glgD Streptococcus pneumoniae P1031 glucose-1-phosphate adenylyltransferase, GlgD subunit YP_002738274.1 1035589 D 488223 CDS YP_002738275.1 225856764 7682488 1036725..1038158 1 NC_012467.1 catalyzes the formation of alpha-1,4-glucan chains from ADP-glucose; glycogen synthase 1038158 glgA 7682488 glgA Streptococcus pneumoniae P1031 glycogen synthase YP_002738275.1 1036725 D 488223 CDS YP_002738276.1 225856765 7680644 1038871..1039986 1 NC_012467.1 identified by match to protein family HMM PF02595; match to protein family HMM TIGR00045; glycerate kinase 1039986 7680644 SPP_1132 Streptococcus pneumoniae P1031 glycerate kinase YP_002738276.1 1038871 D 488223 CDS YP_002738277.1 225856766 7682253 complement(1039983..1040429) 1 NC_012467.1 identified by match to protein family HMM PF07997; hypothetical protein 1040429 7682253 SPP_1131 Streptococcus pneumoniae P1031 hypothetical protein YP_002738277.1 1039983 R 488223 CDS YP_002738278.1 225856767 7680945 1040593..1041897 1 NC_012467.1 enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis; phosphopyruvate hydratase 1041897 eno 7680945 eno Streptococcus pneumoniae P1031 phosphopyruvate hydratase YP_002738278.1 1040593 D 488223 CDS YP_002738279.1 225856768 7681492 complement(1042035..1042415) 1 NC_012467.1 identified by match to protein family HMM PF00589; integrase/recombinase, phage integrase family protein 1042415 7681492 SPP_1134 Streptococcus pneumoniae P1031 integrase/recombinase, phage integrase family protein YP_002738279.1 1042035 R 488223 CDS YP_002738280.1 225856769 7682500 1042717..1042845 1 NC_012467.1 identified by glimmer; putative; hypothetical protein 1042845 7682500 SPP_1135 Streptococcus pneumoniae P1031 hypothetical protein YP_002738280.1 1042717 D 488223 CDS YP_002738281.1 225856770 7681635 complement(1042864..1043214) 1 NC_012467.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by match to protein family HMM PF01710; transposase 1043214 7681635 SPP_1136 Streptococcus pneumoniae P1031 transposase YP_002738281.1 1042864 R 488223 CDS YP_002738282.1 225856771 7682390 1043740..1047015 1 NC_012467.1 identified by match to protein family HMM TIGR02774; ATP-dependent nuclease subunit B 1047015 rexB 7682390 rexB Streptococcus pneumoniae P1031 ATP-dependent nuclease subunit B YP_002738282.1 1043740 D 488223 CDS YP_002738283.1 225856772 7682693 1047012..1050662 1 NC_012467.1 identified by match to protein family HMM PF00580; match to protein family HMM TIGR02785; recombination helicase AddA 1050662 addA 7682693 addA Streptococcus pneumoniae P1031 recombination helicase AddA YP_002738283.1 1047012 D 488223 CDS YP_002738284.1 225856773 7680816 1050877..1052055 1 NC_012467.1 hypothetical protein 1052055 7680816 SPP_1139 Streptococcus pneumoniae P1031 hypothetical protein YP_002738284.1 1050877 D 488223 CDS YP_002738285.1 225856774 7681798 1052264..1058743 1 NC_012467.1 identified by match to protein family HMM PF00089; match to protein family HMM PF00746; match to protein family HMM PF04650; match to protein family HMM PF05342; match to protein family HMM PF07501; match to protein family HMM PF07580; match to protein family HMM PF07581; match to protein family HMM TIGR01167; match to protein family HMM TIGR01168; IgA1 protease 1058743 7681798 SPP_1140 Streptococcus pneumoniae P1031 IgA1 protease YP_002738285.1 1052264 D 488223 CDS YP_002738286.1 225856775 7682796 1058787..1064000 1 NC_012467.1 identified by match to protein family HMM PF00746; match to protein family HMM PF05342; match to protein family HMM PF07501; match to protein family HMM PF07580; match to protein family HMM TIGR01167; zinc metalloprotease ZmpB 1064000 zmpB2 7682796 zmpB2 Streptococcus pneumoniae P1031 zinc metalloprotease ZmpB YP_002738286.1 1058787 D 488223 CDS YP_002738287.1 225856776 7681869 complement(1064005..1064190) 1 NC_012467.1 identified by glimmer; putative; hypothetical protein 1064190 7681869 SPP_1142 Streptococcus pneumoniae P1031 hypothetical protein YP_002738287.1 1064005 R 488223 CDS YP_002738288.1 225856777 7681260 1064530..1064703 1 NC_012467.1 hypothetical protein 1064703 7681260 SPP_1143 Streptococcus pneumoniae P1031 hypothetical protein YP_002738288.1 1064530 D 488223 CDS YP_002738289.1 225856778 7681300 1064700..1065479 1 NC_012467.1 identified by match to protein family HMM PF06970; replication initiator protein A (RepA) N-terminus 1065479 7681300 SPP_1144 Streptococcus pneumoniae P1031 replication initiator protein A (RepA) N-terminus YP_002738289.1 1064700 D 488223 CDS YP_002738290.1 225856779 7681539 1065578..1066936 1 NC_012467.1 identified by match to protein family HMM PF00145; match to protein family HMM TIGR00675; methyl transferase 1066936 7681539 SPP_1145 Streptococcus pneumoniae P1031 methyl transferase YP_002738290.1 1065578 D 488223 CDS YP_002738291.1 225856780 7682027 1066920..1067369 1 NC_012467.1 hypothetical protein 1067369 7682027 SPP_1146 Streptococcus pneumoniae P1031 hypothetical protein YP_002738291.1 1066920 D 488223 CDS YP_002738292.1 225856781 7682719 1067362..1067742 1 NC_012467.1 hypothetical protein 1067742 7682719 SPP_1147 Streptococcus pneumoniae P1031 hypothetical protein YP_002738292.1 1067362 D 488223 CDS YP_002738293.1 225856782 7682211 1067755..1067988 1 NC_012467.1 hypothetical protein 1067988 7682211 SPP_1148 Streptococcus pneumoniae P1031 hypothetical protein YP_002738293.1 1067755 D 488223 CDS YP_002738294.1 225856783 7682367 1068132..1068593 1 NC_012467.1 identified by match to protein family HMM PF02517; caax amino protease family 1068593 7682367 SPP_1149 Streptococcus pneumoniae P1031 caax amino protease family YP_002738294.1 1068132 D 488223 CDS YP_002738295.1 225856784 7680920 complement(1068755..1069972) 1 NC_012467.1 identified by match to protein family HMM PF00589; match to protein family HMM PF02920; transposase 1069972 7680920 SPP_1150 Streptococcus pneumoniae P1031 transposase YP_002738295.1 1068755 R 488223 CDS YP_002738296.1 225856785 7682176 complement(1070054..1070257) 1 NC_012467.1 identified by match to protein family HMM PF09035; hypothetical protein 1070257 7682176 SPP_1151 Streptococcus pneumoniae P1031 hypothetical protein YP_002738296.1 1070054 R 488223 CDS YP_002738297.1 225856786 7681137 complement(1070945..1071367) 1 NC_012467.1 identified by match to protein family HMM PF04545; match to protein family HMM PF08281; sigma-70, region 4 family 1071367 7681137 SPP_1152 Streptococcus pneumoniae P1031 sigma-70, region 4 family YP_002738297.1 1070945 R 488223 CDS YP_002738298.1 225856787 7682758 1071400..1071516 1 NC_012467.1 identified by glimmer; putative; hypothetical protein 1071516 7682758 SPP_1153 Streptococcus pneumoniae P1031 hypothetical protein YP_002738298.1 1071400 D 488223 CDS YP_002738299.1 225856788 7681678 1071872..1072225 1 NC_012467.1 identified by match to protein family HMM PF01381; transcriptional regulator, putative 1072225 7681678 SPP_1154 Streptococcus pneumoniae P1031 transcriptional regulator, putative YP_002738299.1 1071872 D 488223 CDS YP_002738300.1 225856789 7682206 complement(1072571..1074490) 1 NC_012467.1 identified by match to protein family HMM PF00009; match to protein family HMM PF00679; match to protein family HMM PF03144; match to protein family HMM PF03764; match to protein family HMM TIGR00231; tetracycline resistance protein TetM 1074490 7682206 SPP_1155 Streptococcus pneumoniae P1031 tetracycline resistance protein TetM YP_002738300.1 1072571 R 488223 CDS YP_002738301.1 225856790 7681142 complement(1074506..1074622) 1 NC_012467.1 regulates the transcription of tet(M) by attenuation; tetracycline resistance determinant leader peptide 1074622 7681142 SPP_1156 Streptococcus pneumoniae P1031 tetracycline resistance determinant leader peptide YP_002738301.1 1074506 R 488223 CDS YP_002738302.1 225856791 7682854 complement(1074867..1075784) 1 NC_012467.1 conjugative transposon protein 1075784 7682854 SPP_1157 Streptococcus pneumoniae P1031 conjugative transposon protein YP_002738302.1 1074867 R 488223 CDS YP_002738303.1 225856792 7682071 complement(1075799..1076800) 1 NC_012467.1 identified by match to protein family HMM PF00877; NLP/P60 family protein 1076800 7682071 SPP_1158 Streptococcus pneumoniae P1031 NLP/P60 family protein YP_002738303.1 1075799 R 488223 CDS YP_002738304.1 225856793 7680979 complement(1076797..1078974) 1 NC_012467.1 conjugative transposon membrane protein 1078974 7680979 SPP_1159 Streptococcus pneumoniae P1031 conjugative transposon membrane protein YP_002738304.1 1076797 R 488223 CDS YP_002738305.1 225856794 7680902 complement(1078977..1081424) 1 NC_012467.1 conjugative transposon protein 1081424 7680902 SPP_1160 Streptococcus pneumoniae P1031 conjugative transposon protein YP_002738305.1 1078977 R 488223 CDS YP_002738306.1 225856795 7680817 complement(1081408..1081914) 1 NC_012467.1 conjugative transposon membrane protein 1081914 7680817 SPP_1161 Streptococcus pneumoniae P1031 conjugative transposon membrane protein YP_002738306.1 1081408 R 488223 CDS YP_002738307.1 225856796 7681432 complement(1081889..1082386) 1 NC_012467.1 identified by match to protein family HMM PF07275; conjugative transposon protein 1082386 7681432 SPP_1162 Streptococcus pneumoniae P1031 conjugative transposon protein YP_002738307.1 1081889 R 488223 CDS YP_002738308.1 225856797 7682397 complement(1082503..1082724) 1 NC_012467.1 hypothetical protein 1082724 7682397 SPP_1163 Streptococcus pneumoniae P1031 hypothetical protein YP_002738308.1 1082503 R 488223 CDS YP_002738309.1 225856798 7680896 complement(1082767..1083972) 1 NC_012467.1 identified by match to protein family HMM PF01381; match to protein family HMM PF02486; transcriptional regulator, Cro/CI family 1083972 7680896 SPP_1164 Streptococcus pneumoniae P1031 transcriptional regulator, Cro/CI family YP_002738309.1 1082767 R 488223 CDS YP_002738310.1 225856799 7681330 complement(1084150..1085535) 1 NC_012467.1 identified by match to protein family HMM PF01580; ftsk/spoiiie family protein 1085535 7681330 SPP_1165 Streptococcus pneumoniae P1031 ftsk/spoiiie family protein YP_002738310.1 1084150 R 488223 CDS YP_002738311.1 225856800 7682086 complement(1085564..1085947) 1 NC_012467.1 identified by match to protein family HMM PF06125; conjugative transposon protein 1085947 7682086 SPP_1166 Streptococcus pneumoniae P1031 conjugative transposon protein YP_002738311.1 1085564 R 488223 CDS YP_002738312.1 225856801 7682634 complement(1085966..1086280) 1 NC_012467.1 identified by match to protein family HMM PF06125; conjugative transposon protein 1086280 7682634 SPP_1167 Streptococcus pneumoniae P1031 conjugative transposon protein YP_002738312.1 1085966 R 488223 CDS YP_002738313.1 225856802 7681589 complement(1086303..1086422) 1 NC_012467.1 hypothetical protein 1086422 7681589 SPP_1168 Streptococcus pneumoniae P1031 hypothetical protein YP_002738313.1 1086303 R 488223 CDS YP_002738314.1 225856803 7681749 1086953..1087252 1 NC_012467.1 hypothetical protein 1087252 7681749 SPP_1169 Streptococcus pneumoniae P1031 hypothetical protein YP_002738314.1 1086953 D 488223 CDS YP_002738315.1 225856804 7682197 1087242..1087730 1 NC_012467.1 hypothetical protein 1087730 7682197 SPP_1170 Streptococcus pneumoniae P1031 hypothetical protein YP_002738315.1 1087242 D 488223 CDS YP_002738316.1 225856805 7682372 1087730..1089607 1 NC_012467.1 identified by match to protein family HMM PF02534; TraG/TraD family protein 1089607 7682372 SPP_1171 Streptococcus pneumoniae P1031 TraG/TraD family protein YP_002738316.1 1087730 D 488223 CDS YP_002738317.1 225856806 7681760 1089628..1089870 1 NC_012467.1 hypothetical protein 1089870 7681760 SPP_1172 Streptococcus pneumoniae P1031 hypothetical protein YP_002738317.1 1089628 D 488223 CDS YP_002738318.1 225856807 7681116 1089887..1090741 1 NC_012467.1 hypothetical protein 1090741 7681116 SPP_1173 Streptococcus pneumoniae P1031 hypothetical protein YP_002738318.1 1089887 D 488223 CDS YP_002738319.1 225856808 7681450 1090795..1091154 1 NC_012467.1 hypothetical protein 1091154 7681450 SPP_1174 Streptococcus pneumoniae P1031 hypothetical protein YP_002738319.1 1090795 D 488223 CDS YP_002738320.1 225856809 7680654 1091147..1093462 1 NC_012467.1 hypothetical protein 1093462 7680654 SPP_1175 Streptococcus pneumoniae P1031 hypothetical protein YP_002738320.1 1091147 D 488223 CDS YP_002738321.1 225856810 7682754 1093474..1096287 1 NC_012467.1 identified by match to protein family HMM PF01551; match to protein family HMM PF05257; M23 peptidase domain protein 1096287 7682754 SPP_1176 Streptococcus pneumoniae P1031 M23 peptidase domain protein YP_002738321.1 1093474 D 488223 CDS YP_002738322.1 225856811 7682130 1096525..1097091 1 NC_012467.1 hypothetical protein 1097091 7682130 SPP_1177 Streptococcus pneumoniae P1031 hypothetical protein YP_002738322.1 1096525 D 488223 CDS YP_002738323.1 225856812 7681666 1097243..1097653 1 NC_012467.1 Ig domain protein, group 2 domain protein 1097653 7681666 SPP_1178 Streptococcus pneumoniae P1031 Ig domain protein, group 2 domain protein YP_002738323.1 1097243 D 488223 CDS YP_002738324.1 225856813 7682219 1097701..1103931 1 NC_012467.1 identified by match to protein family HMM PF00176; match to protein family HMM PF00271; match to protein family HMM PF02384; match to protein family HMM PF04851; SNF2 family protein 1103931 7682219 SPP_1179 Streptococcus pneumoniae P1031 SNF2 family protein YP_002738324.1 1097701 D 488223 CDS YP_002738325.1 225856814 7681575 1104006..1104290 1 NC_012467.1 hypothetical protein 1104290 7681575 SPP_1180 Streptococcus pneumoniae P1031 hypothetical protein YP_002738325.1 1104006 D 488223 CDS YP_002738326.1 225856815 7680653 1104304..1104600 1 NC_012467.1 hypothetical protein 1104600 7680653 SPP_1181 Streptococcus pneumoniae P1031 hypothetical protein YP_002738326.1 1104304 D 488223 CDS YP_002738327.1 225856816 7681368 complement(1104614..1104811) 1 NC_012467.1 identified by glimmer; putative; hypothetical protein 1104811 7681368 SPP_1182 Streptococcus pneumoniae P1031 hypothetical protein YP_002738327.1 1104614 R 488223 CDS YP_002738328.1 225856817 7682006 1104971..1105612 1 NC_012467.1 hypothetical protein 1105612 7682006 SPP_1183 Streptococcus pneumoniae P1031 hypothetical protein YP_002738328.1 1104971 D 488223 CDS YP_002738329.1 225856818 7680787 1105622..1106707 1 NC_012467.1 DNA primase 1106707 7680787 SPP_1184 Streptococcus pneumoniae P1031 DNA primase YP_002738329.1 1105622 D 488223 CDS YP_002738330.1 225856819 7681688 1106758..1106991 1 NC_012467.1 hypothetical protein 1106991 7681688 SPP_1185 Streptococcus pneumoniae P1031 hypothetical protein YP_002738330.1 1106758 D 488223 CDS YP_002738331.1 225856820 7681624 1106988..1107371 1 NC_012467.1 methyl-accepting chemotaxis protein 1107371 7681624 SPP_1186 Streptococcus pneumoniae P1031 methyl-accepting chemotaxis protein YP_002738331.1 1106988 D 488223 CDS YP_002738332.1 225856821 7681736 1107409..1107681 1 NC_012467.1 ATPases with chaperone activity, ATP-binding subunit 1107681 7681736 SPP_1187 Streptococcus pneumoniae P1031 ATPases with chaperone activity, ATP-binding subunit YP_002738332.1 1107409 D 488223 CDS YP_002738333.1 225856822 7682170 1107751..1108227 1 NC_012467.1 identified by match to protein family HMM PF01381; helix-turn-helix domain protein 1108227 7682170 SPP_1188 Streptococcus pneumoniae P1031 helix-turn-helix domain protein YP_002738333.1 1107751 D 488223 CDS YP_002738334.1 225856823 7682771 1108227..1108997 1 NC_012467.1 identified by match to protein family HMM PF06414; signal recognition particle GTPase 1108997 7682771 SPP_1189 Streptococcus pneumoniae P1031 signal recognition particle GTPase YP_002738334.1 1108227 D 488223 CDS YP_002738335.1 225856824 7681027 1109225..1109908 1 NC_012467.1 identified by match to protein family HMM PF00717; match to protein family HMM PF01381; transcriptional regulator 1109908 7681027 SPP_1190 Streptococcus pneumoniae P1031 transcriptional regulator YP_002738335.1 1109225 D 488223 CDS YP_002738336.1 225856825 7681221 1109911..1111326 1 NC_012467.1 identified by match to protein family HMM PF00817; SOS responce UmuC protein 1111326 7681221 SPP_1191 Streptococcus pneumoniae P1031 SOS responce UmuC protein YP_002738336.1 1109911 D 488223 CDS YP_002738337.1 225856826 7680820 1111326..1111688 1 NC_012467.1 hypothetical protein 1111688 7680820 SPP_1192 Streptococcus pneumoniae P1031 hypothetical protein YP_002738337.1 1111326 D 488223 CDS YP_002738338.1 225856827 7681488 1111678..1111968 1 NC_012467.1 hypothetical protein 1111968 7681488 SPP_1193 Streptococcus pneumoniae P1031 hypothetical protein YP_002738338.1 1111678 D 488223 CDS YP_002738339.1 225856828 7681010 1112264..1112620 1 NC_012467.1 identified by glimmer; putative; hypothetical protein 1112620 7681010 SPP_1194 Streptococcus pneumoniae P1031 hypothetical protein YP_002738339.1 1112264 D 488223 CDS YP_002738340.1 225856829 7682231 1112763..1112990 1 NC_012467.1 identified by match to protein family HMM PF05713; putative mobilization protein (MobC) 1112990 7682231 SPP_1195 Streptococcus pneumoniae P1031 putative mobilization protein (MobC) YP_002738340.1 1112763 D 488223 CDS YP_002738341.1 225856830 7681134 1112977..1114806 1 NC_012467.1 identified by match to protein family HMM PF03432; relaxase 1114806 7681134 SPP_1196 Streptococcus pneumoniae P1031 relaxase YP_002738341.1 1112977 D 488223 CDS YP_002738342.1 225856831 7681656 1114910..1115134 1 NC_012467.1 identified by match to protein family HMM PF01381; hypothetical protein 1115134 7681656 SPP_1197 Streptococcus pneumoniae P1031 hypothetical protein YP_002738342.1 1114910 D 488223 CDS YP_002738343.1 225856832 7682560 1115722..1117230 1 NC_012467.1 identified by match to protein family HMM PF00589; integrase 1117230 7682560 SPP_1198 Streptococcus pneumoniae P1031 integrase YP_002738343.1 1115722 D 488223 CDS YP_002738344.1 225856833 7681498 1117312..1118163 1 NC_012467.1 essential GTPase; functions in ribosome assembly; binds a unique part of the 23S rRNA; interacts with ribosomal protein L25(Ctc); ribosomal biogenesis GTPase 1118163 rbgA 7681498 rbgA Streptococcus pneumoniae P1031 ribosomal biogenesis GTPase YP_002738344.1 1117312 D 488223 CDS YP_002738345.1 225856834 7682585 1118150..1118929 1 NC_012467.1 RNH2; RNase HII; binds manganese; endonuclease which specifically degrades the RNA of RNA-DNA hybrids; ribonuclease HII 1118929 rnhB 7682585 rnhB Streptococcus pneumoniae P1031 ribonuclease HII YP_002738345.1 1118150 D 488223 CDS YP_002738346.1 225856835 7682741 1118945..1120495 1 NC_012467.1 identified by match to protein family HMM PF00654; match to protein family HMM PF02080; voltage-gated chloride channel family protein 1120495 7682741 SPP_1201 Streptococcus pneumoniae P1031 voltage-gated chloride channel family protein YP_002738346.1 1118945 D 488223 CDS YP_002738347.1 225856836 7681788 1120989..1122059 1 NC_012467.1 site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; cell division protein FtsK may regulate the XerS; site-specific tyrosine recombinase XerS 1122059 xerS 7681788 xerS Streptococcus pneumoniae P1031 site-specific tyrosine recombinase XerS YP_002738347.1 1120989 D 488223 CDS YP_002738348.1 225856837 7682381 complement(1122132..1123121) 1 NC_012467.1 identified by match to protein family HMM PF03099; match to protein family HMM TIGR00545; lipoate protein ligase A 1123121 7682381 SPP_1203 Streptococcus pneumoniae P1031 lipoate protein ligase A YP_002738348.1 1122132 R 488223 CDS YP_002738349.1 225856838 7680861 complement(1123185..1124888) 1 NC_012467.1 identified by match to protein family HMM PF00070; match to protein family HMM PF00364; match to protein family HMM PF01134; match to protein family HMM PF02852; match to protein family HMM PF03486; match to protein family HMM PF07992; match to protein family HMM TIGR01350; dihydrolipoyl dehydrogenase 1124888 lpdA 7680861 lpdA Streptococcus pneumoniae P1031 dihydrolipoyl dehydrogenase YP_002738349.1 1123185 R 488223 CDS YP_002738350.1 225856839 7682518 complement(1124934..1125977) 1 NC_012467.1 unlike PdhC proteins from other organisms, some Mycoplasma lack an N-terminal lipoyl domain; in Mycoplasma hyopneumonia the PdhD proteins contains the lipoyl domain; dihydrolipoamide acetyltransferase 1125977 7682518 SPP_1205 Streptococcus pneumoniae P1031 dihydrolipoamide acetyltransferase YP_002738350.1 1124934 R 488223 CDS YP_002738351.1 225856840 7681447 complement(1126195..1127187) 1 NC_012467.1 identified by match to protein family HMM PF02779; match to protein family HMM PF02780; pyruvate dehydrogenase E1 component subunit beta 1127187 7681447 SPP_1206 Streptococcus pneumoniae P1031 pyruvate dehydrogenase E1 component subunit beta YP_002738351.1 1126195 R 488223 CDS YP_002738352.1 225856841 7682689 complement(1127203..1128171) 1 NC_012467.1 identified by match to protein family HMM PF00676; pyruvate dehydrogenase E1 component subunit alpha 1128171 7682689 SPP_1207 Streptococcus pneumoniae P1031 pyruvate dehydrogenase E1 component subunit alpha YP_002738352.1 1127203 R 488223 CDS YP_002738353.1 225856842 7681002 complement(1128325..1129686) 1 NC_012467.1 identified by match to protein family HMM PF01554; match to protein family HMM TIGR00797; mate efflux family protein 1129686 7681002 SPP_1208 Streptococcus pneumoniae P1031 mate efflux family protein YP_002738353.1 1128325 R 488223 CDS YP_002738354.1 225856843 7681740 complement(1129971..1131239) 1 NC_012467.1 catalyzes the formation of N-carbamoyl-L-aspartate from (S)-dihydroorotate in pyrimidine biosynthesis; dihydroorotase 1131239 pyrC 7681740 pyrC Streptococcus pneumoniae P1031 dihydroorotase YP_002738354.1 1129971 R 488223 CDS YP_002738355.1 225856844 7681572 complement(1131252..1131716) 1 NC_012467.1 identified by match to protein family HMM PF00293; mutator MutT protein (7,8-dihydro-8-oxoguanine-triphosphatase) (8-oxo-dGTPase) (dGTP pyrophosphohydrolase) 1131716 7681572 SPP_1210 Streptococcus pneumoniae P1031 mutator MutT protein (7,8-dihydro-8-oxoguanine-triphosphatase) (8-oxo-dGTPase) (dGTP pyrophosphohydrolase) YP_002738355.1 1131252 R 488223 CDS YP_002738356.1 225856845 7682358 complement(1131726..1132379) 1 NC_012467.1 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine; uracil-DNA glycosylase 1132379 ung 7682358 ung Streptococcus pneumoniae P1031 uracil-DNA glycosylase YP_002738356.1 1131726 R 488223 CDS YP_002738357.1 225856846 7681366 complement(1132517..1133164) 1 NC_012467.1 hypothetical protein 1133164 7681366 SPP_1212 Streptococcus pneumoniae P1031 hypothetical protein YP_002738357.1 1132517 R 488223 CDS YP_002738358.1 225856847 7682140 complement(1133178..1133891) 1 NC_012467.1 identified by match to protein family HMM PF00702; match to protein family HMM TIGR01549; match to protein family HMM TIGR02254; HAD superfamily (subfamily IA) hydrolase 1133891 7682140 SPP_1213 Streptococcus pneumoniae P1031 HAD superfamily (subfamily IA) hydrolase YP_002738358.1 1133178 R 488223 CDS YP_002738359.1 225856848 7682686 complement(1134144..1135490) 1 NC_012467.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop; identified by match to protein family HMM PF01609; Spn1 transposase 1135490 7682686 SPP_1214 Streptococcus pneumoniae P1031 Spn1 transposase YP_002738359.1 1134144 R 488223 CDS YP_002738360.1 225856849 7682242 complement(1136859..1139393) 1 NC_012467.1 identified by match to protein family HMM PF04270; match to protein family HMM TIGR01363; pneumococcal histidine triad protein B 1139393 7682242 SPP_1217 Streptococcus pneumoniae P1031 pneumococcal histidine triad protein B YP_002738360.1 1136859 R 488223 CDS YP_002738361.1 225856850 7681379 complement(1139551..1142001) 1 NC_012467.1 identified by match to protein family HMM PF04270; match to protein family HMM TIGR01363; pneumococcal histidine triad protein B 1142001 7681379 SPP_1218 Streptococcus pneumoniae P1031 pneumococcal histidine triad protein B YP_002738361.1 1139551 R 488223 CDS YP_002738362.1 225856851 7681441 1142122..1142259 1 NC_012467.1 identified by glimmer; putative; hypothetical protein 1142259 7681441 SPP_1220 Streptococcus pneumoniae P1031 hypothetical protein YP_002738362.1 1142122 D 488223 CDS YP_002738363.1 225856852 7681600 complement(1142256..1143989) 1 NC_012467.1 identified by match to protein family HMM PF00391; match to protein family HMM PF02896; match to protein family HMM PF05524; match to protein family HMM TIGR01417; phosphoenolpyruvate-protein phosphotransferase 1143989 ptsP 7681600 ptsP Streptococcus pneumoniae P1031 phosphoenolpyruvate-protein phosphotransferase YP_002738363.1 1142256 R 488223 CDS YP_002738364.1 225856853 7680642 complement(1143995..1144258) 1 NC_012467.1 identified by match to protein family HMM PF00381; match to protein family HMM TIGR01003; phosphocarrier protein HPr 1144258 7680642 SPP_1221 Streptococcus pneumoniae P1031 phosphocarrier protein HPr YP_002738364.1 1143995 R 488223 CDS YP_002738365.1 225856854 7681310 1144609..1144827 1 NC_012467.1 identified by match to protein family HMM PF00462; match to protein family HMM TIGR02194; glutaredoxin 1144827 7681310 SPP_1222 Streptococcus pneumoniae P1031 glutaredoxin YP_002738365.1 1144609 D 488223 CDS YP_002738366.1 225856855 7681870 1144908..1147067 1 NC_012467.1 Catalyzes the rate-limiting step in dNTP synthesis; ribonucleotide-diphosphate reductase subunit alpha 1147067 7681870 SPP_1223 Streptococcus pneumoniae P1031 ribonucleotide-diphosphate reductase subunit alpha YP_002738366.1 1144908 D 488223 CDS YP_002738367.1 225856856 7681637 1147255..1148217 1 NC_012467.1 B2 or R2 protein; type 1b enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdE; ribonucleotide-diphosphate reductase subunit beta 1148217 nrdF 7681637 nrdF Streptococcus pneumoniae P1031 ribonucleotide-diphosphate reductase subunit beta YP_002738367.1 1147255 D 488223 CDS YP_002738368.1 225856857 7681349 1148399..1149160 1 NC_012467.1 identified by match to protein family HMM PF00455; match to protein family HMM PF08220; match to protein family HMM PF08279; lactose phosphotransferase system repressor 1149160 7681349 SPP_1225 Streptococcus pneumoniae P1031 lactose phosphotransferase system repressor YP_002738368.1 1148399 D 488223 CDS YP_002738369.1 225856858 7681564 complement(1149439..1149618) 1 NC_012467.1 identified by glimmer; putative; hypothetical protein 1149618 7681564 SPP_1226 Streptococcus pneumoniae P1031 hypothetical protein YP_002738369.1 1149439 R 488223 CDS YP_002738370.1 225856859 7680997 complement(1149741..1151147) 1 NC_012467.1 catalyzes the formation of 6-phospho-galactose from a 6-phospho-beta-galactoside; 6-phospho-beta-galactosidase 1151147 lacG2 7680997 lacG2 Streptococcus pneumoniae P1031 6-phospho-beta-galactosidase YP_002738370.1 1149741 R 488223 CDS YP_002738371.1 225856860 7681094 complement(1151362..1153053) 1 NC_012467.1 identified by match to protein family HMM PF02302; match to protein family HMM PF02378; match to protein family HMM TIGR00394; match to protein family HMM TIGR00410; match to protein family HMM TIGR00853; PTS system, lactose-specific IIC component 1153053 7681094 SPP_1228 Streptococcus pneumoniae P1031 PTS system, lactose-specific IIC component YP_002738371.1 1151362 R 488223 CDS YP_002738372.1 225856861 7680875 complement(1153053..1153370) 1 NC_012467.1 identified by match to protein family HMM PF02255; match to protein family HMM TIGR00823; lactose-specific phosphotransferase enzyme iia component (pts system lactose-specific eiia component) (eiia-lac) (eiii-lac) 1153370 7680875 SPP_1229 Streptococcus pneumoniae P1031 lactose-specific phosphotransferase enzyme iia component (pts system lactose-specific eiia component) (eiia-lac) (eiii-lac) YP_002738372.1 1153053 R 488223 CDS YP_002738373.1 225856862 7682401 complement(1153406..1154242) 1 NC_012467.1 identified by match to protein family HMM PF00874; match to protein family HMM PF03123; transcription antiterminator LacT 1154242 7682401 SPP_1230 Streptococcus pneumoniae P1031 transcription antiterminator LacT YP_002738373.1 1153406 R 488223 CDS YP_002738374.1 225856863 7682622 complement(1154476..1155456) 1 NC_012467.1 catalyzes the reversible reaction of dihydroxyacetone phosphate with glyceraldehyde 3-phosphate to produce tagatose 1,6-bisphosphate; in Streptococcus pyogenes there are two paralogs of tagatose-bisphosphate aldolase, encoded by lacD1 and lacD2; expression of lacD1 is highly regulated by environmental conditions while lacD2 specializes in an efficient utilization of carbohydrate sources; tagatose 1,6-diphosphate aldolase 1155456 lacD 7682622 lacD Streptococcus pneumoniae P1031 tagatose 1,6-diphosphate aldolase YP_002738374.1 1154476 R 488223 CDS YP_002738375.1 225856864 7680790 complement(1155458..1156387) 1 NC_012467.1 catalyzes the formation of tagatose 1,6-bisphosphate from tagatose 6-phosphate and ATP; tagatose-6-phosphate kinase 1156387 lacC 7680790 lacC Streptococcus pneumoniae P1031 tagatose-6-phosphate kinase YP_002738375.1 1155458 R 488223 CDS YP_002738376.1 225856865 7682869 complement(1156398..1156913) 1 NC_012467.1 catalyzes the interconversion of galactose 6-phosphate to tagatose 6-phosphate; galactose-6-phosphate isomerase subunit LacB 1156913 lacB 7682869 lacB Streptococcus pneumoniae P1031 galactose-6-phosphate isomerase subunit LacB YP_002738376.1 1156398 R 488223 CDS YP_002738377.1 225856866 7682635 complement(1156944..1157369) 1 NC_012467.1 catalyzes the interconversion of galactose 6-phosphate to tagatose 6-phosphate; tagatose pathway for galactose utilization; galactose-6-phosphate isomerase subunit LacA 1157369 lacA 7682635 lacA Streptococcus pneumoniae P1031 galactose-6-phosphate isomerase subunit LacA YP_002738377.1 1156944 R 488223 CDS YP_002738378.1 225856867 7681438 complement(1157527..1157871) 1 NC_012467.1 identified by glimmer; putative; hypothetical protein 1157871 7681438 SPP_1235 Streptococcus pneumoniae P1031 hypothetical protein YP_002738378.1 1157527 R 488223 CDS YP_002738379.1 225856868 7682225 complement(1158040..1158429) 1 NC_012467.1 identified by match to protein family HMM PF01609; transposase (IS4 family) 1158429 7682225 SPP_1236 Streptococcus pneumoniae P1031 transposase (IS4 family) YP_002738379.1 1158040 R 488223 CDS YP_002738380.1 225856869 7681396 complement(1158446..1158844) 1 NC_012467.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; mobile genetic element 1158844 7681396 SPP_1237 Streptococcus pneumoniae P1031 mobile genetic element YP_002738380.1 1158446 R 488223 CDS YP_002738381.1 225856870 7682753 complement(1158852..1159154) 1 NC_012467.1 PTS system, galactose-specific IIB component 1159154 7682753 SPP_1238 Streptococcus pneumoniae P1031 PTS system, galactose-specific IIB component YP_002738381.1 1158852 R 488223 CDS YP_002738382.1 225856871 7681538 complement(1159192..1159668) 1 NC_012467.1 identified by match to protein family HMM PF00359; phosphotransferase system sugar-specific EII component 1159668 7681538 SPP_1239 Streptococcus pneumoniae P1031 phosphotransferase system sugar-specific EII component YP_002738382.1 1159192 R 488223 CDS YP_002738383.1 225856872 7681417 1159848..1160045 1 NC_012467.1 chlorohydrolase 1160045 7681417 SPP_1240 Streptococcus pneumoniae P1031 chlorohydrolase YP_002738383.1 1159848 D 488223 CDS YP_002738384.1 225856873 7681275 complement(1160126..1161949) 1 NC_012467.1 binds to the ribosome on the universally-conserved alpha-sarcin loop; GTP-binding protein LepA 1161949 lepA 7681275 lepA Streptococcus pneumoniae P1031 GTP-binding protein LepA YP_002738384.1 1160126 R 488223 CDS YP_002738385.1 225856874 7682452 complement(1162028..1162756) 1 NC_012467.1 identified by match to protein family HMM PF00149; serine/threonine protein phosphatase 1162756 7682452 SPP_1242 Streptococcus pneumoniae P1031 serine/threonine protein phosphatase YP_002738385.1 1162028 R 488223 CDS YP_002738386.1 225856875 7681259 complement(1162758..1164425) 1 NC_012467.1 identified by match to protein family HMM PF02463; match to protein family HMM TIGR00634; DNA repair protein RecN 1164425 recN 7681259 recN Streptococcus pneumoniae P1031 DNA repair protein RecN YP_002738386.1 1162758 R 488223 CDS YP_002738387.1 225856876 7682552 complement(1164432..1164863) 1 NC_012467.1 identified by match to protein family HMM PF01316; match to protein family HMM PF02863; transcriptional regulator of arginine metabolism expression 1164863 7682552 SPP_1244 Streptococcus pneumoniae P1031 transcriptional regulator of arginine metabolism expression YP_002738387.1 1164432 R 488223 CDS YP_002738388.1 225856877 7681752 complement(1164856..1165671) 1 NC_012467.1 identified by match to protein family HMM PF01479; match to protein family HMM PF01728; match to protein family HMM TIGR00478; hemolysin A 1165671 tylA 7681752 tylA Streptococcus pneumoniae P1031 hemolysin A YP_002738388.1 1164856 R 488223 CDS YP_002738389.1 225856878 7682617 complement(1165664..1166539) 1 NC_012467.1 identified by match to protein family HMM PF00348; geranyltranstransferase (Farnesyl-diphosphate synthase)(FPP synthase) 1166539 7682617 SPP_1246 Streptococcus pneumoniae P1031 geranyltranstransferase (Farnesyl-diphosphate synthase)(FPP synthase) YP_002738389.1 1165664 R 488223 CDS YP_002738390.1 225856879 7680641 complement(1166536..1166748) 1 NC_012467.1 catalyzes the bidirectional exonucleolytic cleavage of DNA; exodeoxyribonuclease VII small subunit 1166748 xseB 7680641 xseB Streptococcus pneumoniae P1031 exodeoxyribonuclease VII small subunit YP_002738390.1 1166536 R 488223 CDS YP_002738391.1 225856880 7681591 complement(1166726..1168066) 1 NC_012467.1 bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides; exodeoxyribonuclease VII large subunit 1168066 xseA 7681591 xseA Streptococcus pneumoniae P1031 exodeoxyribonuclease VII large subunit YP_002738391.1 1166726 R 488223 CDS YP_002738392.1 225856881 7680652 complement(1168194..1168832) 1 NC_012467.1 functions in pyrimidine salvage; pyrimidine ribonucleoside kinase; phosphorylates nucleosides or dinucleosides to make UMP or CMP using ATP or GTP as the donor; uridine kinase 1168832 udk 7680652 udk Streptococcus pneumoniae P1031 uridine kinase YP_002738392.1 1168194 R 488223 CDS YP_002738393.1 225856882 7681254 complement(1168940..1169242) 1 NC_012467.1 hypothetical protein 1169242 7681254 SPP_1250 Streptococcus pneumoniae P1031 hypothetical protein YP_002738393.1 1168940 R 488223 CDS YP_002738394.1 225856883 7681733 complement(1169483..1170361) 1 NC_012467.1 catalyzes isomerization of specific uridines in RNA to pseudouridine; responsible for residues in T loops of many tRNAs; tRNA pseudouridine synthase B 1170361 truB 7681733 truB Streptococcus pneumoniae P1031 tRNA pseudouridine synthase B YP_002738394.1 1169483 R 488223 CDS YP_002738395.1 225856884 7682375 complement(1170371..1171645) 1 NC_012467.1 hypothetical protein 1171645 7682375 SPP_1252 Streptococcus pneumoniae P1031 hypothetical protein YP_002738395.1 1170371 R 488223 CDS YP_002738396.1 225856885 7681510 complement(1173148..1173945) 1 NC_012467.1 identified by match to protein family HMM PF01226; formate-nitrate transporter 1173945 7681510 SPP_1255 Streptococcus pneumoniae P1031 formate-nitrate transporter YP_002738396.1 1173148 R 488223 CDS YP_002738397.1 225856886 7682421 complement(1174189..1174932) 1 NC_012467.1 identified by match to protein family HMM PF04203; match to protein family HMM TIGR01076; sortase 1174932 7682421 SPP_1256 Streptococcus pneumoniae P1031 sortase YP_002738397.1 1174189 R 488223 CDS YP_002738398.1 225856887 7681907 complement(1174932..1177400) 1 NC_012467.1 negatively supercoils closed circular double-stranded DNA; DNA gyrase subunit A 1177400 gyrA 7681907 gyrA Streptococcus pneumoniae P1031 DNA gyrase subunit A YP_002738398.1 1174932 R 488223 CDS YP_002738399.1 225856888 7682080 1177594..1178580 1 NC_012467.1 Converts (S)-lactate and NAD(+) to pyruvate and NADH; L-lactate dehydrogenase 1178580 ldh 7682080 ldh Streptococcus pneumoniae P1031 L-lactate dehydrogenase YP_002738399.1 1177594 D 488223 CDS YP_002738400.1 225856889 7680888 complement(1178870..1179613) 1 NC_012467.1 identified by match to protein family HMM PF00520; match to protein family HMM PF07885; potassium/ion channel protein 1179613 7680888 SPP_1259 Streptococcus pneumoniae P1031 potassium/ion channel protein YP_002738400.1 1178870 R 488223 CDS YP_002738401.1 225856890 7681974 complement(1179660..1179914) 1 NC_012467.1 identified by match to protein family HMM PF05016; match to protein family HMM TIGR02385; cytotoxic translational repressor of toxin-antitoxin stability system 1179914 7681974 SPP_1260 Streptococcus pneumoniae P1031 cytotoxic translational repressor of toxin-antitoxin stability system YP_002738401.1 1179660 R 488223 CDS YP_002738402.1 225856891 7681467 complement(1179916..1180158) 1 NC_012467.1 hypothetical protein 1180158 7681467 SPP_1261 Streptococcus pneumoniae P1031 hypothetical protein YP_002738402.1 1179916 R 488223 CDS YP_002738403.1 225856892 7681266 complement(1180249..1181058) 1 NC_012467.1 identified by match to protein family HMM PF00753; VicX protein 1181058 7681266 SPP_1262 Streptococcus pneumoniae P1031 VicX protein YP_002738403.1 1180249 R 488223 CDS YP_002738404.1 225856893 7682789 complement(1181060..1182409) 1 NC_012467.1 identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF00989; match to protein family HMM PF02518; match to protein family HMM TIGR00229; sensor protein YycG 1182409 7682789 SPP_1263 Streptococcus pneumoniae P1031 sensor protein YycG YP_002738404.1 1181060 R 488223 CDS YP_002738405.1 225856894 7680874 complement(1182402..1183106) 1 NC_012467.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00486; alkaline phosphatase synthesis transcriptional regulatory proteinphoP 1183106 7680874 SPP_1264 Streptococcus pneumoniae P1031 alkaline phosphatase synthesis transcriptional regulatory proteinphoP YP_002738405.1 1182402 R 488223 CDS YP_002738406.1 225856895 7680969 complement(1183162..1184337) 1 NC_012467.1 identified by match to protein family HMM PF00633; match to protein family HMM PF00730; match to protein family HMM TIGR01084; A/G-specific adenine glycosylase 1184337 mutY 7680969 mutY Streptococcus pneumoniae P1031 A/G-specific adenine glycosylase YP_002738406.1 1183162 R 488223 CDS YP_002738407.1 225856896 7682324 complement(1184665..1186335) 1 NC_012467.1 catalyzes the formation of 10-formyltetrahydrofolate from formate and tetrahydrofolate; formate--tetrahydrofolate ligase 1186335 fhs 7682324 fhs Streptococcus pneumoniae P1031 formate--tetrahydrofolate ligase YP_002738407.1 1184665 R 488223 CDS YP_002738408.1 225856897 7680655 1186565..1187254 1 NC_012467.1 identified by match to protein family HMM PF04127; match to protein family HMM TIGR02114; phosphopantothenate--cysteine ligase 1187254 coaB 7680655 coaB Streptococcus pneumoniae P1031 phosphopantothenate--cysteine ligase YP_002738408.1 1186565 D 488223 CDS YP_002738409.1 225856898 7682787 1187266..1187817 1 NC_012467.1 decarboxylates 4-phosphopantothenoylcysteine to form 4'-phosphopantotheine.; phosphopantothenoylcysteine decarboxylase 1187817 coaC 7682787 coaC Streptococcus pneumoniae P1031 phosphopantothenoylcysteine decarboxylase YP_002738409.1 1187266 D 488223 CDS YP_002738410.1 225856899 7681304 1187801..1188364 1 NC_012467.1 integral membrane protein 1188364 7681304 SPP_1270 Streptococcus pneumoniae P1031 integral membrane protein YP_002738410.1 1187801 D 488223 CDS YP_002738411.1 225856900 7682075 1188646..1189173 1 NC_012467.1 hypothetical protein 1189173 7682075 SPP_1271 Streptococcus pneumoniae P1031 hypothetical protein YP_002738411.1 1188646 D 488223 CDS YP_002738412.1 225856901 7681963 1189185..1189700 1 NC_012467.1 identified by match to protein family HMM PF02829; match to protein family HMM PF08279; transcriptional regulator, biotin repressor family 1189700 7681963 SPP_1273 Streptococcus pneumoniae P1031 transcriptional regulator, biotin repressor family YP_002738412.1 1189185 D 488223 CDS YP_002738413.1 225856902 7680855 complement(1189697..1190164) 1 NC_012467.1 identified by match to protein family HMM PF00293; NTP pyrophosphohydrolase including oxidative damage repair enzymes 1190164 7680855 SPP_1272 Streptococcus pneumoniae P1031 NTP pyrophosphohydrolase including oxidative damage repair enzymes YP_002738413.1 1189697 R 488223 CDS YP_002738414.1 225856903 7681764 complement(1190238..1190726) 1 NC_012467.1 identified by match to protein family HMM PF00583; acetyltransferase, gnat family 1190726 7681764 SPP_1274 Streptococcus pneumoniae P1031 acetyltransferase, gnat family YP_002738414.1 1190238 R 488223 CDS YP_002738415.1 225856904 7682062 complement(1190692..1191255) 1 NC_012467.1 acetyltransferase, gnat family 1191255 7682062 SPP_1275 Streptococcus pneumoniae P1031 acetyltransferase, gnat family YP_002738415.1 1190692 R 488223 CDS YP_002738416.1 225856905 7681996 complement(1191265..1193253) 1 NC_012467.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion; excinuclease ABC subunit B 1193253 uvrB 7681996 uvrB Streptococcus pneumoniae P1031 excinuclease ABC subunit B YP_002738416.1 1191265 R 488223 CDS YP_002738417.1 225856906 7681051 complement(1193330..1194283) 1 NC_012467.1 identified by match to protein family HMM PF02517; caax amino protease family 1194283 7681051 SPP_1277 Streptococcus pneumoniae P1031 caax amino protease family YP_002738417.1 1193330 R 488223 CDS YP_002738418.1 225856907 7682639 1194456..1196621 1 NC_012467.1 identified by match to protein family HMM PF00497; match to protein family HMM PF00528; match to protein family HMM TIGR01726; amino acid ABC transporter permease/substrate-binding protein 1196621 7682639 SPP_1278 Streptococcus pneumoniae P1031 amino acid ABC transporter permease/substrate-binding protein YP_002738418.1 1194456 D 488223 CDS YP_002738419.1 225856908 7682844 1196621..1197361 1 NC_012467.1 identified by match to protein family HMM PF00005; glutamine transport ATP-binding protein GlnQ 1197361 7682844 SPP_1279 Streptococcus pneumoniae P1031 glutamine transport ATP-binding protein GlnQ YP_002738419.1 1196621 D 488223 CDS YP_002738420.1 225856909 7682713 1197510..1198997 1 NC_012467.1 catalyzes the formation of D-glucono-1,5-lactone 6-phosphate from D-glucose 6-phosphate; glucose-6-phosphate 1-dehydrogenase 1198997 zwf 7682713 zwf Streptococcus pneumoniae P1031 glucose-6-phosphate 1-dehydrogenase YP_002738420.1 1197510 D 488223 CDS YP_002738421.1 225856910 7681771 complement(1199041..1200330) 1 NC_012467.1 identified by match to protein family HMM PF00448; match to protein family HMM PF02881; match to protein family HMM TIGR00064; cell division protein FtsY 1200330 7681771 SPP_1281 Streptococcus pneumoniae P1031 cell division protein FtsY YP_002738421.1 1199041 R 488223 CDS YP_002738422.1 225856911 7681875 complement(1200334..1201152) 1 NC_012467.1 identified by match to protein family HMM PF00702; match to protein family HMM PF08282; match to protein family HMM TIGR00099; match to protein family HMM TIGR01484; Cof family protein 1201152 7681875 SPP_1282 Streptococcus pneumoniae P1031 Cof family protein YP_002738422.1 1200334 R 488223 CDS YP_002738423.1 225856912 7682037 complement(1201152..1201946) 1 NC_012467.1 identified by match to protein family HMM PF00702; match to protein family HMM PF05116; match to protein family HMM PF08282; match to protein family HMM TIGR00099; match to protein family HMM TIGR01484; Cof family protein 1201946 7682037 SPP_1283 Streptococcus pneumoniae P1031 Cof family protein YP_002738423.1 1201152 R 488223 CDS YP_002738424.1 225856913 7682864 complement(1201943..1205482) 1 NC_012467.1 identified by match to protein family HMM PF02463; match to protein family HMM PF06470; match to protein family HMM TIGR02168; chromosome segregation protein SMC 1205482 smc 7682864 smc Streptococcus pneumoniae P1031 chromosome segregation protein SMC YP_002738424.1 1201943 R 488223 CDS YP_002738425.1 225856914 7682621 complement(1205473..1206171) 1 NC_012467.1 cytoplasmic enzyme involved in processing rRNA and some mRNAs; substrates typically have dsRNA regions; forms a homodimer; have N-terminal nuclease and C-terminal RNA-binding domains; requires magnesium as preferred ion for activity; ribonuclease III 1206171 rnc 7682621 rnc Streptococcus pneumoniae P1031 ribonuclease III YP_002738425.1 1205473 R 488223 CDS YP_002738426.1 225856915 7680747 complement(1206489..1207475) 1 NC_012467.1 identified by match to protein family HMM PF00478; match to protein family HMM TIGR01306; guanosine 5'-monophosphate oxidoreductase 1207475 guaC 7680747 guaC Streptococcus pneumoniae P1031 guanosine 5'-monophosphate oxidoreductase YP_002738426.1 1206489 R 488223 CDS YP_002738427.1 225856916 7682276 complement(1207650..1208966) 1 NC_012467.1 hypothetical protein 1208966 7682276 SPP_1288 Streptococcus pneumoniae P1031 hypothetical protein YP_002738427.1 1207650 R 488223 CDS YP_002738428.1 225856917 7680821 complement(1208953..1210866) 1 NC_012467.1 hypothetical protein 1210866 7680821 SPP_1289 Streptococcus pneumoniae P1031 hypothetical protein YP_002738428.1 1208953 R 488223 CDS YP_002738429.1 225856918 7681234 complement(1211815..1212174) 1 NC_012467.1 hypothetical protein 1212174 7681234 SPP_1293 Streptococcus pneumoniae P1031 hypothetical protein YP_002738429.1 1211815 R 488223 CDS YP_002738430.1 225856919 7681855 complement(1212178..1212447) 1 NC_012467.1 identified by match to protein family HMM PF06961; hypothetical protein 1212447 7681855 SPP_1294 Streptococcus pneumoniae P1031 hypothetical protein YP_002738430.1 1212178 R 488223 CDS YP_002738431.1 225856920 7681922 complement(1212444..1213481) 1 NC_012467.1 catalyzes the oxidation of 3-isopropylmalate to 3-carboxy-4-methyl-2-oxopentanoate in leucine biosynthesis; 3-isopropylmalate dehydrogenase 1213481 leuB 7681922 leuB Streptococcus pneumoniae P1031 3-isopropylmalate dehydrogenase YP_002738431.1 1212444 R 488223 CDS YP_002738432.1 225856921 7682786 complement(1214606..1215262) 1 NC_012467.1 identified by match to protein family HMM PF04237; hypothetical protein 1215262 7682786 SPP_1298 Streptococcus pneumoniae P1031 hypothetical protein YP_002738432.1 1214606 R 488223 CDS YP_002738433.1 225856922 7681835 complement(1215306..1215938) 1 NC_012467.1 identified by match to protein family HMM PF03932; copper homeostasis protein CutC 1215938 7681835 SPP_1299 Streptococcus pneumoniae P1031 copper homeostasis protein CutC YP_002738433.1 1215306 R 488223 CDS YP_002738434.1 225856923 7681627 complement(1216031..1216390) 1 NC_012467.1 identified by match to protein family HMM PF04304; hypothetical protein 1216390 7681627 SPP_1300 Streptococcus pneumoniae P1031 hypothetical protein YP_002738434.1 1216031 R 488223 CDS YP_002738435.1 225856924 7682799 complement(1216496..1218583) 1 NC_012467.1 catalyzes the ATP-dependent breakage of single-stranded DNA followed by passage and rejoining, maintains net negative superhelicity; DNA topoisomerase I 1218583 topA 7682799 topA Streptococcus pneumoniae P1031 DNA topoisomerase I YP_002738435.1 1216496 R 488223 CDS YP_002738436.1 225856925 7681570 complement(1218750..1219793) 1 NC_012467.1 identified by match to protein family HMM PF04087; hypothetical protein 1219793 7681570 SPP_1302 Streptococcus pneumoniae P1031 hypothetical protein YP_002738436.1 1218750 R 488223 CDS YP_002738437.1 225856926 7682653 1220371..1220493 1 NC_012467.1 chlorohydrolase 1220493 7682653 SPP_1303 Streptococcus pneumoniae P1031 chlorohydrolase YP_002738437.1 1220371 D 488223 CDS YP_002738438.1 225856927 7681982 complement(1220677..1221525) 1 NC_012467.1 identified by match to protein family HMM PF02481; match to protein family HMM TIGR00732; DNA protecting protein DprA 1221525 dprA 7681982 dprA Streptococcus pneumoniae P1031 DNA protecting protein DprA YP_002738438.1 1220677 R 488223 CDS YP_002738439.1 225856928 7682204 complement(1221623..1222312) 1 NC_012467.1 identified by match to protein family HMM PF00483; LPS epitope expression regulatory protein 1222312 7682204 SPP_1305 Streptococcus pneumoniae P1031 LPS epitope expression regulatory protein YP_002738439.1 1221623 R 488223 CDS YP_002738440.1 225856929 7681250 complement(1222324..1223202) 1 NC_012467.1 identified by match to protein family HMM PF00892; LPS epitope expression regulatory protein 1223202 7681250 SPP_1306 Streptococcus pneumoniae P1031 LPS epitope expression regulatory protein YP_002738440.1 1222324 R 488223 CDS YP_002738441.1 225856930 7682568 complement(1223192..1224061) 1 NC_012467.1 identified by match to protein family HMM PF01633; match to protein family HMM PF01636; choline kinase 1224061 7682568 SPP_1307 Streptococcus pneumoniae P1031 choline kinase YP_002738441.1 1223192 R 488223 CDS YP_002738442.1 225856931 7680959 complement(1224078..1225100) 1 NC_012467.1 identified by match to protein family HMM PF08240; xylitol dehydrogenase 1225100 7680959 SPP_1308 Streptococcus pneumoniae P1031 xylitol dehydrogenase YP_002738442.1 1224078 R 488223 CDS YP_002738443.1 225856932 7681427 complement(1225105..1225812) 1 NC_012467.1 4-diphosphocytidyl-2C-methyl-D-erythritol synthase; MEP cytidylyltransferase; MCT; catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate; involved in isoprenoid and isopentenyl-PP biosynthesis; forms homodimers; 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 1225812 ispD 7681427 ispD Streptococcus pneumoniae P1031 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase YP_002738443.1 1225105 R 488223 CDS YP_002738444.1 225856933 7682720 1226148..1227635 1 NC_012467.1 identified by match to protein family HMM PF01943; match to protein family HMM PF03023; virulence factor mvin superfamily 1227635 7682720 SPP_1310 Streptococcus pneumoniae P1031 virulence factor mvin superfamily YP_002738444.1 1226148 D 488223 CDS YP_002738445.1 225856934 7682502 1227645..1228448 1 NC_012467.1 required for phosphorylcholine incorporation in teichoic and lipoteichoic acids; identified by match to protein family HMM PF04991; phosphotransferase 1228448 7682502 SPP_1311 Streptococcus pneumoniae P1031 phosphotransferase YP_002738445.1 1227645 D 488223 CDS YP_002738446.1 225856935 7681185 1228450..1229259 1 NC_012467.1 identified by match to protein family HMM PF04991; LicD Protein 1229259 7681185 SPP_1312 Streptococcus pneumoniae P1031 LicD Protein YP_002738446.1 1228450 D 488223 CDS YP_002738447.1 225856936 7680676 complement(1229534..1232710) 1 NC_012467.1 four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate; CarB is responsible for the amidotransferase activity; carbamoyl phosphate synthase large subunit 1232710 carB 7680676 carB Streptococcus pneumoniae P1031 carbamoyl phosphate synthase large subunit YP_002738447.1 1229534 R 488223 CDS YP_002738448.1 225856937 7682272 complement(1233023..1234102) 1 NC_012467.1 catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers; carbamoyl phosphate synthase small subunit 1234102 carA 7682272 carA Streptococcus pneumoniae P1031 carbamoyl phosphate synthase small subunit YP_002738448.1 1233023 R 488223 CDS YP_002738449.1 225856938 7680852 complement(1234152..1235075) 1 NC_012467.1 catalyzes the transfer of the carbamoyl moiety from carbamoyl phosphate to L- aspartate in pyrimidine biosynthesis; aspartate carbamoyltransferase catalytic subunit 1235075 pyrB 7680852 pyrB Streptococcus pneumoniae P1031 aspartate carbamoyltransferase catalytic subunit YP_002738449.1 1234152 R 488223 CDS YP_002738450.1 225856939 7682451 complement(1235094..1235615) 1 NC_012467.1 regulates pyrimidine biosynthesis by binding to the mRNA of the pyr genes, also has been shown to have uracil phosphoribosyltransferase activity; bifunctional pyrimidine regulatory protein PyrR uracil phosphoribosyltransferase 1235615 7682451 SPP_1316 Streptococcus pneumoniae P1031 bifunctional pyrimidine regulatory protein PyrR uracil phosphoribosyltransferase YP_002738450.1 1235094 R 488223 CDS YP_002738451.1 225856940 7680784 complement(1235826..1236455) 1 NC_012467.1 identified by match to protein family HMM PF00633; match to protein family HMM PF00730; match to protein family HMM TIGR01083; endonuclease III 1236455 nth 7680784 nth Streptococcus pneumoniae P1031 endonuclease III YP_002738451.1 1235826 R 488223 CDS YP_002738452.1 225856941 7681529 complement(1236455..1236997) 1 NC_012467.1 identified by match to protein family HMM PF02620; hypothetical protein 1236997 7681529 SPP_1318 Streptococcus pneumoniae P1031 hypothetical protein YP_002738452.1 1236455 R 488223 CDS YP_002738453.1 225856942 7681421 1237119..1237307 1 NC_012467.1 identified by glimmer; putative; hypothetical protein 1237307 7681421 SPP_1319 Streptococcus pneumoniae P1031 hypothetical protein YP_002738453.1 1237119 D 488223 CDS YP_002738454.1 225856943 7682318 1237358..1237483 1 NC_012467.1 identified by glimmer; putative; hypothetical protein 1237483 7682318 SPP_1320 Streptococcus pneumoniae P1031 hypothetical protein YP_002738454.1 1237358 D 488223 CDS YP_002738455.1 225856944 7682718 1237722..1239281 1 NC_012467.1 identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 1239281 7682718 SPP_1321 Streptococcus pneumoniae P1031 ABC transporter ATP-binding protein YP_002738455.1 1237722 D 488223 CDS YP_002738456.1 225856945 7682023 complement(1239325..1240224) 1 NC_012467.1 putative metalloprotease; heat shock protein HtpX 1240224 7682023 SPP_1322 Streptococcus pneumoniae P1031 heat shock protein HtpX YP_002738456.1 1239325 R 488223 CDS YP_002738457.1 225856946 7682157 complement(1240226..1240786) 1 NC_012467.1 identified by match to protein family HMM PF04011; cytoplasmic membrane protein 1240786 7682157 SPP_1323 Streptococcus pneumoniae P1031 cytoplasmic membrane protein YP_002738457.1 1240226 R 488223 CDS YP_002738458.1 225856947 7681953 1240880..1241593 1 NC_012467.1 glucose-inhibited division protein B; SAM-dependent methyltransferase; methylates the N7 position of guanosine in position 527 of 16S rRNA; 16S rRNA methyltransferase GidB 1241593 gidB 7681953 gidB Streptococcus pneumoniae P1031 16S rRNA methyltransferase GidB YP_002738458.1 1240880 D 488223 CDS YP_002738459.1 225856948 7682469 1241847..1243130 1 NC_012467.1 identified by match to protein family HMM PF00860; match to protein family HMM TIGR00801; uracil permease (Uracil transporter) 1243130 7682469 SPP_1325 Streptococcus pneumoniae P1031 uracil permease (Uracil transporter) YP_002738459.1 1241847 D 488223 CDS YP_002738460.1 225856949 7681692 complement(1243325..1244896) 1 NC_012467.1 identified by match to protein family HMM PF00448; match to protein family HMM PF02881; match to protein family HMM PF02978; match to protein family HMM TIGR00959; signal recognition particle protein 1244896 ffh 7681692 ffh Streptococcus pneumoniae P1031 signal recognition particle protein YP_002738460.1 1243325 R 488223 CDS YP_002738461.1 225856950 7682782 complement(1244908..1245240) 1 NC_012467.1 identified by match to protein family HMM PF04297; match to protein family HMM PF04967; match to protein family HMM PF08281; putative DNA-binding protein 1245240 7682782 SPP_1327 Streptococcus pneumoniae P1031 putative DNA-binding protein YP_002738461.1 1244908 R 488223 CDS YP_002738462.1 225856951 7681174 complement(1245331..1245696) 1 NC_012467.1 hypothetical protein 1245696 7681174 SPP_1328 Streptococcus pneumoniae P1031 hypothetical protein YP_002738462.1 1245331 R 488223 CDS YP_002738463.1 225856952 7682569 1245780..1247084 1 NC_012467.1 identified by match to protein family HMM PF01966; HD superfamily phosphohydrolase 1247084 7682569 SPP_1329 Streptococcus pneumoniae P1031 HD superfamily phosphohydrolase YP_002738463.1 1245780 D 488223 CDS YP_002738464.1 225856953 7682726 1247097..1247903 1 NC_012467.1 identified by match to protein family HMM PF00702; match to protein family HMM PF05116; match to protein family HMM PF08282; match to protein family HMM TIGR00099; match to protein family HMM TIGR01484; phosphatase YidA 1247903 7682726 SPP_1330 Streptococcus pneumoniae P1031 phosphatase YidA YP_002738464.1 1247097 D 488223 CDS YP_002738465.1 225856954 7682180 1247946..1248944 1 NC_012467.1 identified by match to protein family HMM PF02037; SAP domain protein 1248944 7682180 SPP_1331 Streptococcus pneumoniae P1031 SAP domain protein YP_002738465.1 1247946 D 488223 CDS YP_002738466.1 225856955 7680743 complement(1249223..1249570) 1 NC_012467.1 this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site; 50S ribosomal protein L19 1249570 rplS 7680743 rplS Streptococcus pneumoniae P1031 50S ribosomal protein L19 YP_002738466.1 1249223 R 488223 CDS YP_002738467.1 225856956 7681054 complement(1249689..1250018) 1 NC_012467.1 may be involved in chromosome condensation; overexpression in Escherichia coli protects against decondensation by camphor; overexpressing the protein results in an increase in supercoiling; camphor resistance protein CrcB 1250018 7681054 SPP_1334 Streptococcus pneumoniae P1031 camphor resistance protein CrcB YP_002738467.1 1249689 R 488223 CDS YP_002738468.1 225856957 7682672 complement(1250012..1250386) 1 NC_012467.1 may be involved in chromosome condensation; overexpression in Escherichia coli protects against decondensation by camphor; overexpressing the protein results in an increase in supercoiling; camphor resistance protein CrcB 1250386 7682672 SPP_1335 Streptococcus pneumoniae P1031 camphor resistance protein CrcB YP_002738468.1 1250012 R 488223 CDS YP_002738469.1 225856958 7682329 complement(1250383..1250649) 1 NC_012467.1 identified by match to protein family HMM PF01817; match to protein family HMM TIGR01805; hypothetical protein 1250649 7682329 SPP_1336 Streptococcus pneumoniae P1031 hypothetical protein YP_002738469.1 1250383 R 488223 CDS YP_002738470.1 225856959 7681422 complement(1250765..1251208) 1 NC_012467.1 An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group; flavodoxin 1251208 7681422 SPP_1337 Streptococcus pneumoniae P1031 flavodoxin YP_002738470.1 1250765 R 488223 CDS YP_002738471.1 225856960 7681162 1251312..1252247 1 NC_012467.1 identified by match to protein family HMM PF01368; match to protein family HMM PF02272; DHH subfamily 1 protein 1252247 7681162 SPP_1338 Streptococcus pneumoniae P1031 DHH subfamily 1 protein YP_002738471.1 1251312 D 488223 CDS YP_002738472.1 225856961 7681416 1252343..1252585 1 NC_012467.1 RpmE2; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster do not have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome; 50S ribosomal protein L31 type B 1252585 rpmE2 7681416 rpmE2 Streptococcus pneumoniae P1031 50S ribosomal protein L31 type B YP_002738472.1 1252343 D 488223 CDS YP_002738473.1 225856962 7681036 complement(1252642..1253187) 1 NC_012467.1 high-affinity Fe2+/Pb2+ permease 1253187 7681036 SPP_1340 Streptococcus pneumoniae P1031 high-affinity Fe2+/Pb2+ permease YP_002738473.1 1252642 R 488223 CDS YP_002738474.1 225856963 7681693 complement(1254250..1254654) 1 NC_012467.1 transposase 1254654 7681693 SPP_1343 Streptococcus pneumoniae P1031 transposase YP_002738474.1 1254250 R 488223 CDS YP_002738475.1 225856964 7682092 1255198..1256544 1 NC_012467.1 converts 2-oxoglutarate to glutamate; in Escherichia coli this enzyme plays a role in glutamate synthesis when the cell is under energy restriction; uses NADPH; forms a homohexamer; glutamate dehydrogenase 1256544 7682092 SPP_1344 Streptococcus pneumoniae P1031 glutamate dehydrogenase YP_002738475.1 1255198 D 488223 CDS YP_002738476.1 225856965 7682873 complement(1257040..1257210) 1 NC_012467.1 hypothetical protein 1257210 7682873 SPP_1345 Streptococcus pneumoniae P1031 hypothetical protein YP_002738476.1 1257040 R 488223 CDS YP_002738477.1 225856966 7682627 complement(1257223..1257864) 1 NC_012467.1 identified by match to protein family HMM PF00005; multidrug resistance protein 1 (ATP-binding cassettesub-family B member 1) (P-glycoprotein 1) (antigen) 1257864 7682627 SPP_1346 Streptococcus pneumoniae P1031 multidrug resistance protein 1 (ATP-binding cassettesub-family B member 1) (P-glycoprotein 1) (antigen) YP_002738477.1 1257223 R 488223 CDS YP_002738478.1 225856967 7680936 complement(1258463..1259809) 1 NC_012467.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop; identified by match to protein family HMM PF01609; Spn1 transposase 1259809 7680936 SPP_1347 Streptococcus pneumoniae P1031 Spn1 transposase YP_002738478.1 1258463 R 488223 CDS YP_002738479.1 225856968 7681687 1259986..1260441 1 NC_012467.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; transposase 1260441 7681687 SPP_1348 Streptococcus pneumoniae P1031 transposase YP_002738479.1 1259986 D 488223 CDS YP_002738480.1 225856969 7680627 complement(1260591..1260794) 1 NC_012467.1 glucokinase 1260794 7680627 SPP_1349 Streptococcus pneumoniae P1031 glucokinase YP_002738480.1 1260591 R 488223 CDS YP_002738481.1 225856970 7681926 complement(1260812..1261729) 1 NC_012467.1 identified by match to protein family HMM PF00701; N-acetylneuraminate lyase 1261729 7681926 SPP_1350 Streptococcus pneumoniae P1031 N-acetylneuraminate lyase YP_002738481.1 1260812 R 488223 CDS YP_002738482.1 225856971 7682494 complement(1261761..1262168) 1 NC_012467.1 identified by match to protein family HMM PF00383; match to protein family HMM TIGR01354; cytidine deaminase 1262168 cdd2 7682494 cdd2 Streptococcus pneumoniae P1031 cytidine deaminase YP_002738482.1 1261761 R 488223 CDS YP_002738483.1 225856972 7682085 complement(1262456..1262944) 1 NC_012467.1 identified by match to protein family HMM PF04608; phosphatidylglycerophosphatase A 1262944 pgpA 7682085 pgpA Streptococcus pneumoniae P1031 phosphatidylglycerophosphatase A YP_002738483.1 1262456 R 488223 CDS YP_002738484.1 225856973 7681932 complement(1262949..1264358) 1 NC_012467.1 hypothetical protein 1264358 7681932 SPP_1353 Streptococcus pneumoniae P1031 hypothetical protein YP_002738484.1 1262949 R 488223 CDS YP_002738485.1 225856974 7682793 complement(1264368..1266350) 1 NC_012467.1 identified by match to protein family HMM PF00005; match to protein family HMM PF08352; match to protein family HMM TIGR01727; glutathione ABC transporter, ATP-binding protein 1266350 gsiA 7682793 gsiA Streptococcus pneumoniae P1031 glutathione ABC transporter, ATP-binding protein YP_002738485.1 1264368 R 488223 CDS YP_002738486.1 225856975 7681301 complement(1266363..1267214) 1 NC_012467.1 identified by match to protein family HMM PF00528; oligopeptide transport system permease protein AppC 1267214 7681301 SPP_1355 Streptococcus pneumoniae P1031 oligopeptide transport system permease protein AppC YP_002738486.1 1266363 R 488223 CDS YP_002738487.1 225856976 7681493 complement(1267231..1268181) 1 NC_012467.1 identified by match to protein family HMM PF00528; oligopeptide transport system permease protein AppB 1268181 7681493 SPP_1356 Streptococcus pneumoniae P1031 oligopeptide transport system permease protein AppB YP_002738487.1 1267231 R 488223 CDS YP_002738488.1 225856977 7682259 complement(1268290..1269918) 1 NC_012467.1 identified by match to protein family HMM PF00496; ABC transporter substrate-binding protein - oligopeptide transport 1269918 7682259 SPP_1357 Streptococcus pneumoniae P1031 ABC transporter substrate-binding protein - oligopeptide transport YP_002738488.1 1268290 R 488223 CDS YP_002738489.1 225856978 7682736 complement(1270000..1270923) 1 NC_012467.1 hypothetical protein 1270923 7682736 SPP_1358 Streptococcus pneumoniae P1031 hypothetical protein YP_002738489.1 1270000 R 488223 CDS YP_002738490.1 225856979 7682017 complement(1270947..1271645) 1 NC_012467.1 Converts N-acetylmannosamine-6-phosphate to N-acetylglucosamine-6-phosphate; N-acetylmannosamine-6-phosphate 2-epimerase 1271645 7682017 SPP_1359 Streptococcus pneumoniae P1031 N-acetylmannosamine-6-phosphate 2-epimerase YP_002738490.1 1270947 R 488223 CDS YP_002738491.1 225856980 7682606 complement(1271692..1271955) 1 NC_012467.1 mobile genetic element 1271955 7682606 SPP_1360 Streptococcus pneumoniae P1031 mobile genetic element YP_002738491.1 1271692 R 488223 CDS YP_002738492.1 225856981 7682762 complement(1272538..1272759) 1 NC_012467.1 hypothetical protein 1272759 7682762 SPP_1361 Streptococcus pneumoniae P1031 hypothetical protein YP_002738492.1 1272538 R 488223 CDS YP_002738493.1 225856982 7681746 complement(1273042..1273878) 1 NC_012467.1 identified by match to protein family HMM PF08843; hypothetical protein 1273878 7681746 SPP_1362 Streptococcus pneumoniae P1031 hypothetical protein YP_002738493.1 1273042 R 488223 CDS YP_002738494.1 225856983 7681990 complement(1273878..1274468) 1 NC_012467.1 hypothetical protein 1274468 7681990 SPP_1363 Streptococcus pneumoniae P1031 hypothetical protein YP_002738494.1 1273878 R 488223 CDS YP_002738495.1 225856984 7682030 complement(1274598..1275185) 1 NC_012467.1 identified by match to protein family HMM PF02517; caax amino protease family 1275185 7682030 SPP_1364 Streptococcus pneumoniae P1031 caax amino protease family YP_002738495.1 1274598 R 488223 CDS YP_002738496.1 225856985 7681948 complement(1275188..1275343) 1 NC_012467.1 identified by glimmer; putative; hypothetical protein 1275343 7681948 SPP_1365 Streptococcus pneumoniae P1031 hypothetical protein YP_002738496.1 1275188 R 488223 CDS YP_002738497.1 225856986 7681762 complement(1275434..1275814) 1 NC_012467.1 hypothetical protein 1275814 7681762 SPP_1366 Streptococcus pneumoniae P1031 hypothetical protein YP_002738497.1 1275434 R 488223 CDS YP_002738498.1 225856987 7681062 complement(1275807..1276256) 1 NC_012467.1 hypothetical protein 1276256 7681062 SPP_1367 Streptococcus pneumoniae P1031 hypothetical protein YP_002738498.1 1275807 R 488223 CDS YP_002738499.1 225856988 7681993 complement(1278505..1278678) 1 NC_012467.1 hypothetical protein 1278678 7681993 SPP_1372 Streptococcus pneumoniae P1031 hypothetical protein YP_002738499.1 1278505 R 488223 CDS YP_002738500.1 225856989 7682588 complement(1278865..1279233) 1 NC_012467.1 present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulates GTPase activity of translation factors; 50S ribosomal protein L7/L12 1279233 rplL 7682588 rplL Streptococcus pneumoniae P1031 50S ribosomal protein L7/L12 YP_002738500.1 1278865 R 488223 CDS YP_002738501.1 225856990 7682387 complement(1279309..1279809) 1 NC_012467.1 binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit; 50S ribosomal protein L10 1279809 rplJ 7682387 rplJ Streptococcus pneumoniae P1031 50S ribosomal protein L10 YP_002738501.1 1279309 R 488223 CDS YP_002738502.1 225856991 7682181 complement(1280059..1281480) 1 NC_012467.1 identified by match to protein family HMM PF01979; match to protein family HMM PF07969; chlorohydrolase 1281480 7682181 SPP_1375 Streptococcus pneumoniae P1031 chlorohydrolase YP_002738502.1 1280059 R 488223 CDS YP_002738503.1 225856992 7682819 complement(1281575..1283323) 1 NC_012467.1 identified by match to protein family HMM PF00005; match to protein family HMM PF00664; ABC transporter ATP-binding protein/permease 1283323 7682819 SPP_1376 Streptococcus pneumoniae P1031 ABC transporter ATP-binding protein/permease YP_002738503.1 1281575 R 488223 CDS YP_002738504.1 225856993 7681796 complement(1283325..1285049) 1 NC_012467.1 identified by match to protein family HMM PF00005; match to protein family HMM PF00664; ABC transporter ATP-binding protein/permease 1285049 7681796 SPP_1377 Streptococcus pneumoniae P1031 ABC transporter ATP-binding protein/permease YP_002738504.1 1283325 R 488223 CDS YP_002738505.1 225856994 7680815 complement(1285107..1286045) 1 NC_012467.1 identified by match to protein family HMM PF01625; match to protein family HMM PF01641; match to protein family HMM TIGR00357; match to protein family HMM TIGR00401; peptide methionine sulfoxide reductase MsrA/msrB 1286045 7680815 SPP_1378 Streptococcus pneumoniae P1031 peptide methionine sulfoxide reductase MsrA/msrB YP_002738505.1 1285107 R 488223 CDS YP_002738506.1 225856995 7681522 complement(1286074..1286415) 1 NC_012467.1 hypothetical protein 1286415 7681522 SPP_1379 Streptococcus pneumoniae P1031 hypothetical protein YP_002738506.1 1286074 R 488223 CDS YP_002738507.1 225856996 7681868 complement(1286431..1287300) 1 NC_012467.1 catalyzes the formation of O-phospho-L-homoserine from L-homoserine in threonine biosynthesis from asparate; homoserine kinase 1287300 thrB 7681868 thrB Streptococcus pneumoniae P1031 homoserine kinase YP_002738507.1 1286431 R 488223 CDS YP_002738508.1 225856997 7682299 complement(1287302..1288588) 1 NC_012467.1 catalyzes the formation of L-aspartate 4-semialdehyde from L-homoserine; homoserine dehydrogenase 1288588 7682299 SPP_1381 Streptococcus pneumoniae P1031 homoserine dehydrogenase YP_002738508.1 1287302 R 488223 CDS YP_002738509.1 225856998 7681710 complement(1288739..1289476) 1 NC_012467.1 enables recognition and targeting of proteins for proteolysis, involved in negative regulation of competence; adaptor protein 1289476 7681710 SPP_1382 Streptococcus pneumoniae P1031 adaptor protein YP_002738509.1 1288739 R 488223 CDS YP_002738510.1 225856999 7680878 complement(1289676..1290710) 1 NC_012467.1 hypothetical protein 1290710 7680878 SPP_1383 Streptococcus pneumoniae P1031 hypothetical protein YP_002738510.1 1289676 R 488223 CDS YP_002738511.1 225857000 7680803 complement(1290739..1292172) 1 NC_012467.1 hypothetical protein 1292172 7680803 SPP_1384 Streptococcus pneumoniae P1031 hypothetical protein YP_002738511.1 1290739 R 488223 CDS YP_002738512.1 225857001 7682682 complement(1292188..1293174) 1 NC_012467.1 identified by match to protein family HMM PF00535; glycosyl transferase, family 2 1293174 7682682 SPP_1385 Streptococcus pneumoniae P1031 glycosyl transferase, family 2 YP_002738512.1 1292188 R 488223 CDS YP_002738513.1 225857002 7681079 complement(1293176..1294276) 1 NC_012467.1 identified by match to protein family HMM PF00534; glycosyl transferase, group 1 family protein 1294276 7681079 SPP_1386 Streptococcus pneumoniae P1031 glycosyl transferase, group 1 family protein YP_002738513.1 1293176 R 488223 CDS YP_002738514.1 225857003 7682656 complement(1294269..1295114) 1 NC_012467.1 identified by match to protein family HMM PF04991; licD3 protein 1295114 7682656 SPP_1387 Streptococcus pneumoniae P1031 licD3 protein YP_002738514.1 1294269 R 488223 CDS YP_002738515.1 225857004 7681612 complement(1295393..1296667) 1 NC_012467.1 identified by match to protein family HMM PF03816; match to protein family HMM TIGR00350; transcriptional regulator, LytR family 1296667 7681612 SPP_1388 Streptococcus pneumoniae P1031 transcriptional regulator, LytR family YP_002738515.1 1295393 R 488223 CDS YP_002738516.1 225857005 7682363 complement(1296664..1297512) 1 NC_012467.1 catalyzes the formation of phenylpyruvate from prephenate in phenylalanine biosynthesis; prephenate dehydratase 1297512 7682363 SPP_1389 Streptococcus pneumoniae P1031 prephenate dehydratase YP_002738516.1 1296664 R 488223 CDS YP_002738517.1 225857006 7681369 complement(1297509..1297985) 1 NC_012467.1 identified by match to protein family HMM PF01202; shikimate kinase 1297985 aroK 7681369 aroK Streptococcus pneumoniae P1031 shikimate kinase YP_002738517.1 1297509 R 488223 CDS YP_002738518.1 225857007 7681068 complement(1297978..1299261) 1 NC_012467.1 catalyzes the formation of 5-O-(1-carboxyvinyl)-3-phosphoshikimate from phosphoenolpyruvate and 3-phosphoshikimate in tryptophan biosynthesis; 3-phosphoshikimate 1-carboxyvinyltransferase 1299261 aroA 7681068 aroA Streptococcus pneumoniae P1031 3-phosphoshikimate 1-carboxyvinyltransferase YP_002738518.1 1297978 R 488223 CDS YP_002738519.1 225857008 7682647 complement(1299353..1299691) 1 NC_012467.1 identified by match to protein family HMM PF06133; hypothetical protein 1299691 7682647 SPP_1392 Streptococcus pneumoniae P1031 hypothetical protein YP_002738519.1 1299353 R 488223 CDS YP_002738520.1 225857009 7682405 complement(1299702..1300805) 1 NC_012467.1 catalyzes the formation of 4-hydroxyphenylpyruvate from prephenate; prephenate dehydrogenase 1300805 7682405 SPP_1393 Streptococcus pneumoniae P1031 prephenate dehydrogenase YP_002738520.1 1299702 R 488223 CDS YP_002738521.1 225857010 7682224 complement(1300815..1301981) 1 NC_012467.1 catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis; chorismate synthase 1301981 aroC 7682224 aroC Streptococcus pneumoniae P1031 chorismate synthase YP_002738521.1 1300815 R 488223 CDS YP_002738522.1 225857011 7681150 complement(1301991..1303058) 1 NC_012467.1 catalyzes the formation of 3-dehydroquinate from 3-deoxy-arabino-heptulonate 7-phosphate; functions in aromatic amino acid biosynthesis; 3-dehydroquinate synthase 1303058 aroB 7681150 aroB Streptococcus pneumoniae P1031 3-dehydroquinate synthase YP_002738522.1 1301991 R 488223 CDS YP_002738523.1 225857012 7682862 complement(1303077..1303931) 1 NC_012467.1 AroE; catalyzes the conversion of shikimate to 3-dehydroshikimate; shikimate 5-dehydrogenase 1303931 aroE 7682862 aroE Streptococcus pneumoniae P1031 shikimate 5-dehydrogenase YP_002738523.1 1303077 R 488223 CDS YP_002738524.1 225857013 7681873 complement(1303921..1304598) 1 NC_012467.1 catalyzes the dehydration of 3-dehydroquinate to form 3-dehydroshikimate in aromatic amino acid biosynthesis; 3-dehydroquinate dehydratase 1304598 aroD 7681873 aroD Streptococcus pneumoniae P1031 3-dehydroquinate dehydratase YP_002738524.1 1303921 R 488223 CDS YP_002738525.1 225857014 7681775 complement(1304595..1305758) 1 NC_012467.1 methyltransferase 1305758 7681775 SPP_1398 Streptococcus pneumoniae P1031 methyltransferase YP_002738525.1 1304595 R 488223 CDS YP_002738526.1 225857015 7681501 complement(1306445..1308079) 1 NC_012467.1 hypothetical protein 1308079 7681501 SPP_1399 Streptococcus pneumoniae P1031 hypothetical protein YP_002738526.1 1306445 R 488223 CDS YP_002738527.1 225857016 7680972 complement(1308060..1308809) 1 NC_012467.1 identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 1308809 7680972 SPP_1400 Streptococcus pneumoniae P1031 ABC transporter ATP-binding protein YP_002738527.1 1308060 R 488223 CDS YP_002738528.1 225857017 7681483 1308988..1310442 1 NC_012467.1 converts 1,4-alpha-D-glucans to maltodextrin; cytoplasmic alpha-amylase 1310442 7681483 SPP_1401 Streptococcus pneumoniae P1031 cytoplasmic alpha-amylase YP_002738528.1 1308988 D 488223 CDS YP_002738529.1 225857018 7680690 complement(1310531..1313149) 1 NC_012467.1 Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; alanyl-tRNA synthetase 1313149 alaS 7680690 alaS Streptococcus pneumoniae P1031 alanyl-tRNA synthetase YP_002738529.1 1310531 R 488223 CDS YP_002738530.1 225857019 7682090 complement(1313171..1313656) 1 NC_012467.1 identified by match to protein family HMM PF04525; hypothetical protein 1313656 7682090 SPP_1403 Streptococcus pneumoniae P1031 hypothetical protein YP_002738530.1 1313171 R 488223 CDS YP_002738531.1 225857020 7681307 complement(1313931..1314170) 1 NC_012467.1 hypothetical protein 1314170 7681307 SPP_1404 Streptococcus pneumoniae P1031 hypothetical protein YP_002738531.1 1313931 R 488223 CDS YP_002738532.1 225857021 7681989 complement(1314431..1315501) 1 NC_012467.1 identified by match to protein family HMM PF01547; spermidine/putrescine ABC transporter, spermidine/putrescine-binding protein 1315501 7681989 SPP_1405 Streptococcus pneumoniae P1031 spermidine/putrescine ABC transporter, spermidine/putrescine-binding protein YP_002738532.1 1314431 R 488223 CDS YP_002738533.1 225857022 7681574 complement(1315498..1316271) 1 NC_012467.1 identified by match to protein family HMM PF00528; spermidine/putrescine ABC transporter permease 1316271 7681574 SPP_1406 Streptococcus pneumoniae P1031 spermidine/putrescine ABC transporter permease YP_002738533.1 1315498 R 488223 CDS YP_002738534.1 225857023 7681588 complement(1316268..1317074) 1 NC_012467.1 identified by match to protein family HMM PF00528; spermidine/putrescine ABC transporter permease 1317074 7681588 SPP_1407 Streptococcus pneumoniae P1031 spermidine/putrescine ABC transporter permease YP_002738534.1 1316268 R 488223 CDS YP_002738535.1 225857024 7680625 complement(1317055..1318212) 1 NC_012467.1 identified by match to protein family HMM PF00005; match to protein family HMM PF08402; spermidine/putrescine import ATP-binding protein PotA 1318212 7680625 SPP_1408 Streptococcus pneumoniae P1031 spermidine/putrescine import ATP-binding protein PotA YP_002738535.1 1317055 R 488223 CDS YP_002738536.1 225857025 7681121 complement(1318372..1319277) 1 NC_012467.1 catalyzes the reduction of UDP-N-acetylglucosamine enolpyruvate to form UDP-N-acetylmuramate in peptidoglycan biosynthesis; UDP-N-acetylenolpyruvoylglucosamine reductase 1319277 murB 7681121 murB Streptococcus pneumoniae P1031 UDP-N-acetylenolpyruvoylglucosamine reductase YP_002738536.1 1318372 R 488223 CDS YP_002738537.1 225857026 7682675 complement(1319389..1320141) 1 NC_012467.1 hypothetical protein 1320141 7682675 SPP_1410 Streptococcus pneumoniae P1031 hypothetical protein YP_002738537.1 1319389 R 488223 CDS YP_002738538.1 225857027 7682338 complement(1320151..1320882) 1 NC_012467.1 identified by match to protein family HMM PF03306; match to protein family HMM TIGR01252; alpha-acetolactate decarboxylase 1320882 budA 7682338 budA Streptococcus pneumoniae P1031 alpha-acetolactate decarboxylase YP_002738538.1 1320151 R 488223 CDS YP_002738539.1 225857028 7681491 1321024..1322295 1 NC_012467.1 identified by match to protein family HMM PF00392; GntR family transcriptional regulator 1322295 7681491 SPP_1412 Streptococcus pneumoniae P1031 GntR family transcriptional regulator YP_002738539.1 1321024 D 488223 CDS YP_002738540.1 225857029 7682015 complement(1322315..1323001) 1 NC_012467.1 identified by match to protein family HMM PF00497; amino acid ABC transporter substrate-binding protein 1323001 7682015 SPP_1413 Streptococcus pneumoniae P1031 amino acid ABC transporter substrate-binding protein YP_002738540.1 1322315 R 488223 CDS YP_002738541.1 225857030 7682746 complement(1323298..1323951) 1 NC_012467.1 identified by match to protein family HMM PF01895; match to protein family HMM TIGR02135; phosphate transport system regulatory protein PhoU 1323951 phoU1 7682746 phoU1 Streptococcus pneumoniae P1031 phosphate transport system regulatory protein PhoU YP_002738541.1 1323298 R 488223 CDS YP_002738542.1 225857031 7681599 complement(1323963..1324721) 1 NC_012467.1 ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation; phosphate transporter ATP-binding protein 1324721 pstB1 7681599 pstB1 Streptococcus pneumoniae P1031 phosphate transporter ATP-binding protein YP_002738542.1 1323963 R 488223 CDS YP_002738543.1 225857032 7682743 complement(1324734..1325537) 1 NC_012467.1 ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation; phosphate transporter ATP-binding protein 1325537 pstB2 7682743 pstB2 Streptococcus pneumoniae P1031 phosphate transporter ATP-binding protein YP_002738543.1 1324734 R 488223 CDS YP_002738544.1 225857033 7682051 complement(1325548..1326432) 1 NC_012467.1 identified by match to protein family HMM PF00528; match to protein family HMM TIGR00974; phosphate ABC transporter permease 1326432 pstA1 7682051 pstA1 Streptococcus pneumoniae P1031 phosphate ABC transporter permease YP_002738544.1 1325548 R 488223 CDS YP_002738545.1 225857034 7682512 complement(1326422..1327339) 1 NC_012467.1 identified by match to protein family HMM PF00528; match to protein family HMM TIGR02138; phosphate ABC transporter permease 1327339 pstC1 7682512 pstC1 Streptococcus pneumoniae P1031 phosphate ABC transporter permease YP_002738545.1 1326422 R 488223 CDS YP_002738546.1 225857035 7681935 complement(1327339..1328217) 1 NC_012467.1 identified by match to protein family HMM PF01547; match to protein family HMM TIGR02136; phosphate-binding protein PstS 1 (PBP 1) 1328217 7681935 SPP_1419 Streptococcus pneumoniae P1031 phosphate-binding protein PstS 1 (PBP 1) YP_002738546.1 1327339 R 488223 CDS YP_002738547.1 225857036 7681689 1328447..1328560 1 NC_012467.1 hypothetical protein 1328560 7681689 SPP_1420 Streptococcus pneumoniae P1031 hypothetical protein YP_002738547.1 1328447 D 488223 CDS YP_002738548.1 225857037 7682133 complement(1328791..1330095) 1 NC_012467.1 identified by match to protein family HMM PF01189; NOL1/NOP2/sun family protein 1330095 7682133 SPP_1421 Streptococcus pneumoniae P1031 NOL1/NOP2/sun family protein YP_002738548.1 1328791 R 488223 CDS YP_002738549.1 225857038 7681865 complement(1330096..1330869) 1 NC_012467.1 identified by match to protein family HMM PF00459; inositol monophosphatase family protein 1330869 7681865 SPP_1422 Streptococcus pneumoniae P1031 inositol monophosphatase family protein YP_002738549.1 1330096 R 488223 CDS YP_002738550.1 225857039 7681536 complement(1330859..1331137) 1 NC_012467.1 identified by match to protein family HMM PF05256; hypothetical protein 1331137 7681536 SPP_1423 Streptococcus pneumoniae P1031 hypothetical protein YP_002738550.1 1330859 R 488223 CDS YP_002738551.1 225857040 7681169 complement(1331137..1331538) 1 NC_012467.1 the anti-alpha factor Spx interacts with RNA polymerase alpha subunit C-terminal domain in a region that interacts with the sigma 70 subunit and may interfere with activation of promoters; in Bacillus subtilis this protein is a substrate for ClpXP protease; blocks transcription of the competence regulatory gene encoded by the srf operon; regulates a number of genes involved in thiol homeostasis including trxA and trxB; monomeric member of ArsC family of proteins; does not bind DNA; contains a disulfide bond between C10 and C13 which may sense disulfide stress; transcriptional regulator Spx 1331538 spxA 7681169 spxA Streptococcus pneumoniae P1031 transcriptional regulator Spx YP_002738551.1 1331137 R 488223 CDS YP_002738552.1 225857041 7681823 complement(1331748..1332365) 1 NC_012467.1 identified by match to protein family HMM PF07314; match to protein family HMM TIGR01906; integral membrane protein 1332365 7681823 SPP_1425 Streptococcus pneumoniae P1031 integral membrane protein YP_002738552.1 1331748 R 488223 CDS YP_002738553.1 225857042 7682872 complement(1332355..1333128) 1 NC_012467.1 identified by match to protein family HMM PF00702; match to protein family HMM TIGR01457; match to protein family HMM TIGR01460; HAD-superfamily subfamily IIA hydrolase 1333128 7682872 SPP_1426 Streptococcus pneumoniae P1031 HAD-superfamily subfamily IIA hydrolase YP_002738553.1 1332355 R 488223 CDS YP_002738554.1 225857043 7680867 complement(1333139..1333876) 1 NC_012467.1 identified by match to protein family HMM PF01643; acyl-ACP thioesterase 1333876 7680867 SPP_1427 Streptococcus pneumoniae P1031 acyl-ACP thioesterase YP_002738554.1 1333139 R 488223 CDS YP_002738555.1 225857044 7681336 complement(1333881..1335011) 1 NC_012467.1 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III; coproporphyrinogen III oxidase 1335011 7681336 SPP_1428 Streptococcus pneumoniae P1031 coproporphyrinogen III oxidase YP_002738555.1 1333881 R 488223 CDS YP_002738556.1 225857045 7681329 complement(1335095..1335484) 1 NC_012467.1 hypothetical protein 1335484 7681329 SPP_1429 Streptococcus pneumoniae P1031 hypothetical protein YP_002738556.1 1335095 R 488223 CDS YP_002738557.1 225857046 7682120 complement(1335500..1335883) 1 NC_012467.1 identified by match to protein family HMM PF06103; hypothetical protein 1335883 7682120 SPP_1430 Streptococcus pneumoniae P1031 hypothetical protein YP_002738557.1 1335500 R 488223 CDS YP_002738558.1 225857047 7681708 complement(1335884..1336672) 1 NC_012467.1 transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein; prolipoprotein diacylglyceryl transferase 1336672 lgt 7681708 lgt Streptococcus pneumoniae P1031 prolipoprotein diacylglyceryl transferase YP_002738558.1 1335884 R 488223 CDS YP_002738559.1 225857048 7682815 complement(1336665..1337600) 1 NC_012467.1 catalyzes the phosphorylation of the phosphocarrier protein HPr of the bacterial phosphotransferase system; HPr kinase/phosphorylase 1337600 hprK 7682815 hprK Streptococcus pneumoniae P1031 HPr kinase/phosphorylase YP_002738559.1 1336665 R 488223 CDS YP_002738560.1 225857049 7682044 complement(1337730..1337906) 1 NC_012467.1 a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA; 30S ribosomal protein S21 1337906 rpsU 7682044 rpsU Streptococcus pneumoniae P1031 30S ribosomal protein S21 YP_002738560.1 1337730 R 488223 CDS YP_002738561.1 225857050 7681114 complement(1338046..1338753) 1 NC_012467.1 identified by match to protein family HMM PF01182; glucosamine-6-phosphate deaminase (glucosamine-6-phosphate isomerase) (gnpda) (glcn6p deaminase) 1338753 7681114 SPP_1434 Streptococcus pneumoniae P1031 glucosamine-6-phosphate deaminase (glucosamine-6-phosphate isomerase) (gnpda) (glcn6p deaminase) YP_002738561.1 1338046 R 488223 CDS YP_002738562.1 225857051 7681783 1338904..1339932 1 NC_012467.1 Synthesizes oQ from preQ1 in a single S-adenosylmethionine-requiring step; S-adenosylmethionine:tRNA ribosyltransferase-isomerase 1339932 queA 7681783 queA Streptococcus pneumoniae P1031 S-adenosylmethionine:tRNA ribosyltransferase-isomerase YP_002738562.1 1338904 D 488223 CDS YP_002738563.1 225857052 7682323 complement(1340593..1340982) 1 NC_012467.1 identified by match to protein family HMM PF01473; choline binding protein 1340982 7682323 SPP_1436 Streptococcus pneumoniae P1031 choline binding protein YP_002738563.1 1340593 R 488223 CDS YP_002738564.1 225857053 7682852 complement(1342442..1342993) 1 NC_012467.1 identified by match to protein family HMM PF00583; acetyltransferase, gnat family 1342993 7682852 SPP_1437 Streptococcus pneumoniae P1031 acetyltransferase, gnat family YP_002738564.1 1342442 R 488223 CDS YP_002738565.1 225857054 7682648 complement(1343343..1344167) 1 NC_012467.1 catalyzes the formation of nicotinamide adenine dinucleotide (NAD) from nicotinic acid adenine dinucleotide (NAAD) using either ammonia or glutamine as the amide donor and ATP; ammonia-utilizing enzymes include the ones from Bacillus and Escherichia coli while glutamine-utilizing enzymes include the Mycobacterial one; forms homodimers; NAD synthetase 1344167 nadE 7682648 nadE Streptococcus pneumoniae P1031 NAD synthetase YP_002738565.1 1343343 R 488223 CDS YP_002738566.1 225857055 7681341 complement(1344164..1345624) 1 NC_012467.1 catalyzes the formation of 5-phospho-alpha-D-ribose 1-diphosphate and nicotinate from nicotinate D-ribonucleotide and diphosphate; nicotinate phosphoribosyltransferase 1345624 pncB 7681341 pncB Streptococcus pneumoniae P1031 nicotinate phosphoribosyltransferase YP_002738566.1 1344164 R 488223 CDS YP_002738567.1 225857056 7680880 complement(1345740..1346228) 1 NC_012467.1 hypothetical protein 1346228 7680880 SPP_1440 Streptococcus pneumoniae P1031 hypothetical protein YP_002738567.1 1345740 R 488223 CDS YP_002738568.1 225857057 7682344 complement(1346218..1346427) 1 NC_012467.1 identified by match to protein family HMM PF01381; hypothetical protein 1346427 7682344 SPP_1441 Streptococcus pneumoniae P1031 hypothetical protein YP_002738568.1 1346218 R 488223 CDS YP_002738569.1 225857058 7682673 complement(1346892..1347293) 1 NC_012467.1 identified by glimmer; putative; hypothetical protein 1347293 7682673 SPP_1442 Streptococcus pneumoniae P1031 hypothetical protein YP_002738569.1 1346892 R 488223 CDS YP_002738570.1 225857059 7682099 complement(1348343..1348456) 1 NC_012467.1 identified by glimmer; putative; hypothetical protein 1348456 7682099 SPP_1445 Streptococcus pneumoniae P1031 hypothetical protein YP_002738570.1 1348343 R 488223 CDS YP_002738571.1 225857060 7681655 complement(1349501..1349812) 1 NC_012467.1 identified by glimmer; putative; hypothetical protein 1349812 7681655 SPP_1448 Streptococcus pneumoniae P1031 hypothetical protein YP_002738571.1 1349501 R 488223 CDS YP_002738572.1 225857061 7680853 complement(1349827..1351113) 1 NC_012467.1 identified by match to protein family HMM PF01136; peptidase, U32 family protein 1351113 7680853 SPP_1449 Streptococcus pneumoniae P1031 peptidase, U32 family protein YP_002738572.1 1349827 R 488223 CDS YP_002738573.1 225857062 7680651 1352286..1353476 1 NC_012467.1 identified by match to protein family HMM PF01555; DNA modification methyltransferase M.XbaI 1353476 7680651 SPP_1452 Streptococcus pneumoniae P1031 DNA modification methyltransferase M.XbaI YP_002738573.1 1352286 D 488223 CDS YP_002738574.1 225857063 7681297 1353723..1353869 1 NC_012467.1 hypothetical protein 1353869 7681297 SPP_1453 Streptococcus pneumoniae P1031 hypothetical protein YP_002738574.1 1353723 D 488223 CDS YP_002738575.1 225857064 7682081 complement(1353991..1354983) 1 NC_012467.1 identified by match to protein family HMM PF00165; AraC family transcriptional regulator 1354983 7682081 SPP_1454 Streptococcus pneumoniae P1031 AraC family transcriptional regulator YP_002738575.1 1353991 R 488223 CDS YP_002738576.1 225857065 7682468 1355143..1356897 1 NC_012467.1 identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein/permease 1356897 7682468 SPP_1455 Streptococcus pneumoniae P1031 ABC transporter ATP-binding protein/permease YP_002738576.1 1355143 D 488223 CDS YP_002738577.1 225857066 7681966 1356881..1358602 1 NC_012467.1 identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 1358602 7681966 SPP_1456 Streptococcus pneumoniae P1031 ABC transporter ATP-binding protein YP_002738577.1 1356881 D 488223 CDS YP_002738578.1 225857067 7681414 1358613..1359197 1 NC_012467.1 identified by match to protein family HMM TIGR02185; hypothetical protein 1359197 7681414 SPP_1457 Streptococcus pneumoniae P1031 hypothetical protein YP_002738578.1 1358613 D 488223 CDS YP_002738579.1 225857068 7680636 1359197..1359892 1 NC_012467.1 identified by match to protein family HMM PF02361; cobalt transport protein 1359892 7680636 SPP_1458 Streptococcus pneumoniae P1031 cobalt transport protein YP_002738579.1 1359197 D 488223 CDS YP_002738580.1 225857069 7680851 1359880..1361244 1 NC_012467.1 identified by match to protein family HMM PF00005; cobalt ABC transporter, ATPase component, CbiO 1361244 7680851 SPP_1459 Streptococcus pneumoniae P1031 cobalt ABC transporter, ATPase component, CbiO YP_002738580.1 1359880 D 488223 CDS YP_002738581.1 225857070 7682398 complement(1362544..1362855) 1 NC_012467.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop; transposase 1362855 7682398 SPP_1461 Streptococcus pneumoniae P1031 transposase YP_002738581.1 1362544 R 488223 CDS YP_002738582.1 225857071 7681884 complement(1362874..1363341) 1 NC_012467.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop; transposase 1363341 7681884 SPP_1462 Streptococcus pneumoniae P1031 transposase YP_002738582.1 1362874 R 488223 CDS YP_002738583.1 225857072 7681698 complement(1363244..1363438) 1 NC_012467.1 identified by glimmer; putative; hypothetical protein 1363438 7681698 SPP_1463 Streptococcus pneumoniae P1031 hypothetical protein YP_002738583.1 1363244 R 488223 CDS YP_002738584.1 225857073 7682289 complement(1363722..1363958) 1 NC_012467.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop; identified by match to protein family HMM PF05717; transposase 1363958 7682289 SPP_1464 Streptococcus pneumoniae P1031 transposase YP_002738584.1 1363722 R 488223 CDS YP_002738585.1 225857074 7681324 complement(1363939..1364124) 1 NC_012467.1 hypothetical protein 1364124 7681324 SPP_1465 Streptococcus pneumoniae P1031 hypothetical protein YP_002738585.1 1363939 R 488223 CDS YP_002738586.1 225857075 7681801 complement(1364428..1365990) 1 NC_012467.1 contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway; GMP synthase 1365990 guaA 7681801 guaA Streptococcus pneumoniae P1031 GMP synthase YP_002738586.1 1364428 R 488223 CDS YP_002738587.1 225857076 7680892 1366132..1366830 1 NC_012467.1 identified by match to protein family HMM PF00392; match to protein family HMM PF07702; GntR family transcriptional regulator 1366830 7680892 SPP_1467 Streptococcus pneumoniae P1031 GntR family transcriptional regulator YP_002738587.1 1366132 D 488223 CDS YP_002738588.1 225857077 7680977 complement(1366873..1367769) 1 NC_012467.1 identified by match to protein family HMM PF00892; membrane protein 1367769 7680977 SPP_1468 Streptococcus pneumoniae P1031 membrane protein YP_002738588.1 1366873 R 488223 CDS YP_002738589.1 225857078 7681489 complement(1367778..1368713) 1 NC_012467.1 identified by match to protein family HMM PF00144; beta-lactamase 1368713 7681489 SPP_1469 Streptococcus pneumoniae P1031 beta-lactamase YP_002738589.1 1367778 R 488223 CDS YP_002738590.1 225857079 7681130 complement(1368710..1369435) 1 NC_012467.1 CppA protein 1369435 7681130 SPP_1470 Streptococcus pneumoniae P1031 CppA protein YP_002738590.1 1368710 R 488223 CDS YP_002738591.1 225857080 7682763 complement(1369519..1370154) 1 NC_012467.1 identified by match to protein family HMM PF00657; hypothetical protein 1370154 7682763 SPP_1471 Streptococcus pneumoniae P1031 hypothetical protein YP_002738591.1 1369519 R 488223 CDS YP_002738592.1 225857081 7681881 complement(1370156..1370983) 1 NC_012467.1 identified by match to protein family HMM PF00702; match to protein family HMM PF05116; match to protein family HMM PF08282; match to protein family HMM TIGR00099; match to protein family HMM TIGR01484; hypothetical protein 1370983 7681881 SPP_1472 Streptococcus pneumoniae P1031 hypothetical protein YP_002738592.1 1370156 R 488223 CDS YP_002738593.1 225857082 7680804 1372503..1373114 1 NC_012467.1 cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+); peptide deformylase 1373114 def 7680804 def Streptococcus pneumoniae P1031 peptide deformylase YP_002738593.1 1372503 D 488223 CDS YP_002738594.1 225857083 7681084 1373159..1373887 1 NC_012467.1 identified by match to protein family HMM PF00588; match to protein family HMM PF08032; match to protein family HMM TIGR00186; RNA methyltransferase, TrmH family, group 3 1373887 7681084 SPP_1477 Streptococcus pneumoniae P1031 RNA methyltransferase, TrmH family, group 3 YP_002738594.1 1373159 D 488223 CDS YP_002738595.1 225857084 7682561 complement(1373926..1374837) 1 NC_012467.1 identified by match to protein family HMM PF00070; match to protein family HMM PF01134; match to protein family HMM PF03486; match to protein family HMM PF07992; match to protein family HMM TIGR01292; thioredoxin-disulfide reductase 1374837 trxB 7682561 trxB Streptococcus pneumoniae P1031 thioredoxin-disulfide reductase YP_002738595.1 1373926 R 488223 CDS YP_002738596.1 225857085 7682464 complement(1374903..1375127) 1 NC_012467.1 hypothetical protein 1375127 7682464 SPP_1479 Streptococcus pneumoniae P1031 hypothetical protein YP_002738596.1 1374903 R 488223 CDS YP_002738597.1 225857086 7681936 complement(1375205..1375948) 1 NC_012467.1 identified by match to protein family HMM PF00005; L-cystine import ATP-binding protein TcyN 1375948 7681936 SPP_1480 Streptococcus pneumoniae P1031 L-cystine import ATP-binding protein TcyN YP_002738597.1 1375205 R 488223 CDS YP_002738598.1 225857087 7681293 complement(1375948..1376748) 1 NC_012467.1 identified by match to protein family HMM PF00528; match to protein family HMM TIGR01726; aspartate/glutamate ABC transporter permease 1376748 7681293 SPP_1481 Streptococcus pneumoniae P1031 aspartate/glutamate ABC transporter permease YP_002738598.1 1375948 R 488223 CDS YP_002738599.1 225857088 7681240 complement(1376906..1377262) 1 NC_012467.1 identified by match to protein family HMM PF03960; match to protein family HMM TIGR01617; arsenate reductase 1377262 7681240 SPP_1482 Streptococcus pneumoniae P1031 arsenate reductase YP_002738599.1 1376906 R 488223 CDS YP_002738600.1 225857089 7681347 complement(1377275..1377787) 1 NC_012467.1 identified by match to protein family HMM PF01035; match to protein family HMM TIGR00589; O6-methylguanine-DNA methyltransferase 1377787 7681347 SPP_1483 Streptococcus pneumoniae P1031 O6-methylguanine-DNA methyltransferase YP_002738600.1 1377275 R 488223 CDS YP_002738601.1 225857090 7681882 complement(1377787..1378281) 1 NC_012467.1 identified by match to protein family HMM PF00583; acetyltransferase, gnat family 1378281 7681882 SPP_1484 Streptococcus pneumoniae P1031 acetyltransferase, gnat family YP_002738601.1 1377787 R 488223 CDS YP_002738602.1 225857091 7682457 1378416..1378862 1 NC_012467.1 identified by match to protein family HMM PF08876; hypothetical protein 1378862 7682457 SPP_1485 Streptococcus pneumoniae P1031 hypothetical protein YP_002738602.1 1378416 D 488223 CDS YP_002738603.1 225857092 7681921 1378859..1379506 1 NC_012467.1 identified by match to protein family HMM PF03006; match to protein family HMM TIGR01065; hemolysin-3 (Hemolysin III) (Hly-III) 1379506 7681921 SPP_1486 Streptococcus pneumoniae P1031 hemolysin-3 (Hemolysin III) (Hly-III) YP_002738603.1 1378859 D 488223 CDS YP_002738604.1 225857093 7682107 complement(1379527..1380108) 1 NC_012467.1 with PdxST is involved in the biosynthesis of pyridoxal 5'-phosphate; PdxT catalyzes the hydrolysis of glutamine to glutamate and ammonia; PdxS utilizes the ammonia to synthesize pyridoxal 5'-phosphate; glutamine amidotransferase subunit PdxT 1380108 7682107 SPP_1487 Streptococcus pneumoniae P1031 glutamine amidotransferase subunit PdxT YP_002738604.1 1379527 R 488223 CDS YP_002738605.1 225857094 7680678 complement(1380109..1380984) 1 NC_012467.1 with PdxT forms pyridoxal 5'-phosphate from glutamine, either ribose 5-phosphate or ribulose 5-phosphate, and either glyceraldehyde 3-phosphate or dihydroxyacetone phosphate; pyridoxal biosynthesis lyase PdxS 1380984 7680678 SPP_1488 Streptococcus pneumoniae P1031 pyridoxal biosynthesis lyase PdxS YP_002738605.1 1380109 R 488223 CDS YP_002738606.1 225857095 7681949 complement(1381136..1382515) 1 NC_012467.1 identified by match to protein family HMM PF00070; match to protein family HMM PF02852; match to protein family HMM PF07992; NADH oxidase (noxase) 1382515 7681949 SPP_1489 Streptococcus pneumoniae P1031 NADH oxidase (noxase) YP_002738606.1 1381136 R 488223 CDS YP_002738607.1 225857096 7682474 1382657..1382812 1 NC_012467.1 hypothetical protein 1382812 7682474 SPP_1490 Streptococcus pneumoniae P1031 hypothetical protein YP_002738607.1 1382657 D 488223 CDS YP_002738608.1 225857097 7682851 1382809..1383732 1 NC_012467.1 identified by match to protein family HMM PF02424; thiamine biosynthesis lipoprotein 1383732 7682851 SPP_1491 Streptococcus pneumoniae P1031 thiamine biosynthesis lipoprotein YP_002738608.1 1382809 D 488223 CDS YP_002738609.1 225857098 7682667 1383792..1384397 1 NC_012467.1 identified by match to protein family HMM PF03358; NADPH-dependent fmn reductase domain protein 1384397 7682667 SPP_1492 Streptococcus pneumoniae P1031 NADPH-dependent fmn reductase domain protein YP_002738609.1 1383792 D 488223 CDS YP_002738610.1 225857099 7681145 1384416..1385660 1 NC_012467.1 identified by match to protein family HMM PF03358; NADPH-dependent fmn reductase domain protein 1385660 7681145 SPP_1493 Streptococcus pneumoniae P1031 NADPH-dependent fmn reductase domain protein YP_002738610.1 1384416 D 488223 CDS YP_002738611.1 225857100 7681702 complement(1385883..1386140) 1 NC_012467.1 identified by match to protein family HMM PF05979; hypothetical protein 1386140 7681702 SPP_1494 Streptococcus pneumoniae P1031 hypothetical protein YP_002738611.1 1385883 R 488223 CDS YP_002738612.1 225857101 7681626 complement(1386182..1388218) 1 NC_012467.1 glycine--tRNA ligase beta chain; glyS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; glycyl-tRNA synthetase subunit beta 1388218 glyS 7681626 glyS Streptococcus pneumoniae P1031 glycyl-tRNA synthetase subunit beta YP_002738612.1 1386182 R 488223 CDS YP_002738613.1 225857102 7681827 complement(1388478..1389395) 1 NC_012467.1 glycine--tRNA ligase alpha chain; GlyRS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; glycyl-tRNA synthetase subunit alpha 1389395 glyQ 7681827 glyQ Streptococcus pneumoniae P1031 glycyl-tRNA synthetase subunit alpha YP_002738613.1 1388478 R 488223 CDS YP_002738614.1 225857103 7681436 complement(1389764..1390090) 1 NC_012467.1 identified by glimmer; putative; hypothetical protein 1390090 7681436 SPP_1497 Streptococcus pneumoniae P1031 hypothetical protein YP_002738614.1 1389764 R 488223 CDS YP_002738615.1 225857104 7681077 complement(1390057..1390341) 1 NC_012467.1 identified by glimmer; putative; hypothetical protein 1390341 7681077 SPP_1498 Streptococcus pneumoniae P1031 hypothetical protein YP_002738615.1 1390057 R 488223 CDS YP_002738616.1 225857105 7682104 complement(1390614..1391456) 1 NC_012467.1 identified by match to protein family HMM PF00248; 2,5-diketo-d-gluconic acid reductase a (2,5-dkgreductase a) (2,5-dkgr a) (25dkgr-a) (akr5c) 1391456 7682104 SPP_1499 Streptococcus pneumoniae P1031 2,5-diketo-d-gluconic acid reductase a (2,5-dkgreductase a) (2,5-dkgr a) (25dkgr-a) (akr5c) YP_002738616.1 1390614 R 488223 CDS YP_002738617.1 225857106 7680695 complement(1391570..1392907) 1 NC_012467.1 identified by match to protein family HMM PF01522; peptidoglycan GlcNAc deacetylase 1392907 7680695 SPP_1500 Streptococcus pneumoniae P1031 peptidoglycan GlcNAc deacetylase YP_002738617.1 1391570 R 488223 CDS YP_002738618.1 225857107 7682480 complement(1393196..1393573) 1 NC_012467.1 hypothetical protein 1393573 7682480 SPP_1501 Streptococcus pneumoniae P1031 hypothetical protein YP_002738618.1 1393196 R 488223 CDS YP_002738619.1 225857108 7681952 1393788..1394765 1 NC_012467.1 identified by match to protein family HMM PF01118; match to protein family HMM PF01408; oxidoreductase 1394765 7681952 SPP_1502 Streptococcus pneumoniae P1031 oxidoreductase YP_002738619.1 1393788 D 488223 CDS YP_002738620.1 225857109 7682427 1394762..1395844 1 NC_012467.1 identified by match to protein family HMM PF00270; match to protein family HMM PF00271; DEAD RNA helicase 1395844 7682427 SPP_1503 Streptococcus pneumoniae P1031 DEAD RNA helicase YP_002738620.1 1394762 D 488223 CDS YP_002738621.1 225857110 7682346 complement(1396003..1396560) 1 NC_012467.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; transposase 1396560 7682346 SPP_1504 Streptococcus pneumoniae P1031 transposase YP_002738621.1 1396003 R 488223 CDS YP_002738622.1 225857111 7681356 complement(1396448..1396714) 1 NC_012467.1 transposase 1396714 7681356 SPP_1505 Streptococcus pneumoniae P1031 transposase YP_002738622.1 1396448 R 488223 CDS YP_002738623.1 225857112 7681053 complement(1396835..1396954) 1 NC_012467.1 identified by glimmer; putative; hypothetical protein 1396954 7681053 SPP_1506 Streptococcus pneumoniae P1031 hypothetical protein YP_002738623.1 1396835 R 488223 CDS YP_002738624.1 225857113 7682704 complement(1397338..1398534) 1 NC_012467.1 EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu; elongation factor Tu 1398534 tuf 7682704 tuf Streptococcus pneumoniae P1031 elongation factor Tu YP_002738624.1 1397338 R 488223 CDS YP_002738625.1 225857114 7682868 complement(1398877..1398999) 1 NC_012467.1 hypothetical protein 1398999 7682868 SPP_1508 Streptococcus pneumoniae P1031 hypothetical protein YP_002738625.1 1398877 R 488223 CDS YP_002738626.1 225857115 7682557 complement(1399410..1400279) 1 NC_012467.1 identified by match to protein family HMM PF00230; glycerol facilitator-aquaporin gla (Aquaglyceroporin)(Glyceroaquaporin) 1400279 7682557 SPP_1509 Streptococcus pneumoniae P1031 glycerol facilitator-aquaporin gla (Aquaglyceroporin)(Glyceroaquaporin) YP_002738626.1 1399410 R 488223 CDS YP_002738627.1 225857116 7681091 complement(1400304..1400426) 1 NC_012467.1 identified by glimmer; putative; hypothetical protein 1400426 7681091 SPP_1510 Streptococcus pneumoniae P1031 hypothetical protein YP_002738627.1 1400304 R 488223 CDS YP_002738628.1 225857117 7682193 complement(1400502..1401182) 1 NC_012467.1 identified by match to protein family HMM PF00746; match to protein family HMM PF06458; match to protein family HMM TIGR01167; MucBP domain family 1401182 7682193 SPP_1511 Streptococcus pneumoniae P1031 MucBP domain family YP_002738628.1 1400502 R 488223 CDS YP_002738629.1 225857118 7682108 complement(1401140..1402054) 1 NC_012467.1 hypothetical protein 1402054 7682108 SPP_1512 Streptococcus pneumoniae P1031 hypothetical protein YP_002738629.1 1401140 R 488223 CDS YP_002738630.1 225857119 7680662 complement(1402182..1402379) 1 NC_012467.1 identified by glimmer; putative; hypothetical protein 1402379 7680662 SPP_1513 Streptococcus pneumoniae P1031 hypothetical protein YP_002738630.1 1402182 R 488223 CDS YP_002738631.1 225857120 7681986 complement(1402357..1402611) 1 NC_012467.1 hypothetical protein 1402611 7681986 SPP_1514 Streptococcus pneumoniae P1031 hypothetical protein YP_002738631.1 1402357 R 488223 CDS YP_002738632.1 225857121 7681904 complement(1402969..1403502) 1 NC_012467.1 transposase 1403502 7681904 SPP_1515 Streptococcus pneumoniae P1031 transposase YP_002738632.1 1402969 R 488223 CDS YP_002738633.1 225857122 7681030 complement(1403489..1403623) 1 NC_012467.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; transposase 1403623 7681030 SPP_1516 Streptococcus pneumoniae P1031 transposase YP_002738633.1 1403489 R 488223 CDS YP_002738634.1 225857123 7682057 complement(1403671..1403814) 1 NC_012467.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; transposase 1403814 7682057 SPP_1517 Streptococcus pneumoniae P1031 transposase YP_002738634.1 1403671 R 488223 CDS YP_002738635.1 225857124 7682217 1404048..1405766 1 NC_012467.1 identified by match to protein family HMM PF00408; match to protein family HMM PF02878; match to protein family HMM PF02879; match to protein family HMM PF02880; phosphomannomutase 1405766 7682217 SPP_1518 Streptococcus pneumoniae P1031 phosphomannomutase YP_002738635.1 1404048 D 488223 CDS YP_002738636.1 225857125 7682296 1405877..1406224 1 NC_012467.1 identified by match to protein family HMM TIGR01295; bacterocin transport accessory protein 1406224 7682296 SPP_1519 Streptococcus pneumoniae P1031 bacterocin transport accessory protein YP_002738636.1 1405877 D 488223 CDS YP_002738637.1 225857126 7682178 complement(1406502..1407338) 1 NC_012467.1 identified by match to protein family HMM PF00497; ABC transporter substrate-binding protein - glutamine transport 1407338 7682178 SPP_1520 Streptococcus pneumoniae P1031 ABC transporter substrate-binding protein - glutamine transport YP_002738637.1 1406502 R 488223 CDS YP_002738638.1 225857127 7681098 complement(1407351..1407980) 1 NC_012467.1 identified by match to protein family HMM PF00005; glutamine transport ATP-binding protein GlnQ 1407980 7681098 SPP_1521 Streptococcus pneumoniae P1031 glutamine transport ATP-binding protein GlnQ YP_002738638.1 1407351 R 488223 CDS YP_002738639.1 225857128 7682171 complement(1407990..1408631) 1 NC_012467.1 identified by match to protein family HMM PF00528; match to protein family HMM TIGR01726; amino acid ABC transporter permease 1408631 7682171 SPP_1522 Streptococcus pneumoniae P1031 amino acid ABC transporter permease YP_002738639.1 1407990 R 488223 CDS YP_002738640.1 225857129 7681153 complement(1408777..1410006) 1 NC_012467.1 identified by match to protein family HMM PF00515; match to protein family HMM PF07719; TPR domain protein 1410006 7681153 SPP_1523 Streptococcus pneumoniae P1031 TPR domain protein YP_002738640.1 1408777 R 488223 CDS YP_002738641.1 225857130 7682716 complement(1409996..1411162) 1 NC_012467.1 identified by match to protein family HMM PF01594; transport protein 1411162 7682716 SPP_1524 Streptococcus pneumoniae P1031 transport protein YP_002738641.1 1409996 R 488223 CDS YP_002738642.1 225857131 7680885 1411306..1412319 1 NC_012467.1 3-carboxymuconate cyclase 1412319 7680885 SPP_1525 Streptococcus pneumoniae P1031 3-carboxymuconate cyclase YP_002738642.1 1411306 D 488223 CDS YP_002738643.1 225857132 7680797 complement(1412364..1412783) 1 NC_012467.1 part of catalytic core of ATP synthase; alpha(3)beta(3)gamma(1)delta(1)epsilon(1); involved in producing ATP from ADP in the presence of the proton motive force across the membrane; F0F1 ATP synthase subunit epsilon 1412783 atpC 7680797 atpC Streptococcus pneumoniae P1031 F0F1 ATP synthase subunit epsilon YP_002738643.1 1412364 R 488223 CDS YP_002738644.1 225857133 7681913 complement(1412794..1414200) 1 NC_012467.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit; F0F1 ATP synthase subunit beta 1414200 atpD 7681913 atpD Streptococcus pneumoniae P1031 F0F1 ATP synthase subunit beta YP_002738644.1 1412794 R 488223 CDS YP_002738645.1 225857134 7682810 complement(1414286..1415164) 1 NC_012467.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is a regulatory subunit; F0F1 ATP synthase subunit gamma 1415164 atpG 7682810 atpG Streptococcus pneumoniae P1031 F0F1 ATP synthase subunit gamma YP_002738645.1 1414286 R 488223 CDS YP_002738646.1 225857135 7681439 complement(1415180..1416685) 1 NC_012467.1 produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit; F0F1 ATP synthase subunit alpha 1416685 atpA 7681439 atpA Streptococcus pneumoniae P1031 F0F1 ATP synthase subunit alpha YP_002738646.1 1415180 R 488223 CDS YP_002738647.1 225857136 7682156 complement(1416700..1417236) 1 NC_012467.1 Produces ATP from ADP in the presence of a proton gradient across the membrane; the delta subunit is part of the catalytic core of the ATP synthase complex; F0F1 ATP synthase subunit delta 1417236 atpH 7682156 atpH Streptococcus pneumoniae P1031 F0F1 ATP synthase subunit delta YP_002738647.1 1416700 R 488223 CDS YP_002738648.1 225857137 7681480 complement(1417236..1417730) 1 NC_012467.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit B is part of the membrane proton channel.; F0F1 ATP synthase subunit B 1417730 atpF 7681480 atpF Streptococcus pneumoniae P1031 F0F1 ATP synthase subunit B YP_002738648.1 1417236 R 488223 CDS YP_002738649.1 225857138 7681124 complement(1417744..1418460) 1 NC_012467.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0; F0F1 ATP synthase subunit A 1418460 atpB 7681124 atpB Streptococcus pneumoniae P1031 F0F1 ATP synthase subunit A YP_002738649.1 1417744 R 488223 CDS YP_002738650.1 225857139 7682220 complement(1418495..1418695) 1 NC_012467.1 produces ATP from ADP in the presence of a proton gradient across the membrane; subunit C is part of the membrane proton channel F0; F0F1 ATP synthase subunit C 1418695 7682220 SPP_1533 Streptococcus pneumoniae P1031 F0F1 ATP synthase subunit C YP_002738650.1 1418495 R 488223 CDS YP_002738651.1 225857140 7682266 complement(1418770..1419777) 1 NC_012467.1 identified by match to protein family HMM PF00665; transposase 1419777 7682266 SPP_1534 Streptococcus pneumoniae P1031 transposase YP_002738651.1 1418770 R 488223 CDS YP_002738652.1 225857141 7682454 1420741..1421109 1 NC_012467.1 chlorohydrolase 1421109 7682454 SPP_1536 Streptococcus pneumoniae P1031 chlorohydrolase YP_002738652.1 1420741 D 488223 CDS YP_002738653.1 225857142 7681526 complement(1421166..1421648) 1 NC_012467.1 necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus; transcription elongation factor GreA 1421648 greA 7681526 greA Streptococcus pneumoniae P1031 transcription elongation factor GreA YP_002738653.1 1421166 R 488223 CDS YP_002738654.1 225857143 7682654 complement(1421719..1423374) 1 NC_012467.1 identified by match to protein family HMM PF02618; match to protein family HMM TIGR00247; aminodeoxychorismate lyase 1423374 7682654 SPP_1538 Streptococcus pneumoniae P1031 aminodeoxychorismate lyase YP_002738654.1 1421719 R 488223 CDS YP_002738655.1 225857144 7682201 complement(1423455..1423949) 1 NC_012467.1 identified by match to protein family HMM PF00583; acetyltransferase, gnat family 1423949 7682201 SPP_1539 Streptococcus pneumoniae P1031 acetyltransferase, gnat family YP_002738655.1 1423455 R 488223 CDS YP_002738656.1 225857145 7682443 complement(1423946..1424410) 1 NC_012467.1 identified by match to protein family HMM PF00583; acetyltransferase, gnat family 1424410 7682443 SPP_1540 Streptococcus pneumoniae P1031 acetyltransferase, gnat family YP_002738656.1 1423946 R 488223 CDS YP_002738657.1 225857146 7680661 complement(1424420..1425754) 1 NC_012467.1 Catalyzes the formation of UDP-N-acetylmuramoyl-L-alanine from UDP-N-acetylmuramate and L-alanine in peptidoglycan synthesis; UDP-N-acetylmuramate--L-alanine ligase 1425754 murC 7680661 murC Streptococcus pneumoniae P1031 UDP-N-acetylmuramate--L-alanine ligase YP_002738657.1 1424420 R 488223 CDS YP_002738658.1 225857147 7682749 complement(1425765..1426382) 1 NC_012467.1 hypothetical protein 1426382 7682749 SPP_1542 Streptococcus pneumoniae P1031 hypothetical protein YP_002738658.1 1425765 R 488223 CDS YP_002738659.1 225857148 7682417 complement(1426430..1429528) 1 NC_012467.1 identified by match to protein family HMM PF00176; match to protein family HMM PF00271; match to protein family HMM PF04434; match to protein family HMM PF08455; Snf2 family protein 1429528 7682417 SPP_1543 Streptococcus pneumoniae P1031 Snf2 family protein YP_002738659.1 1426430 R 488223 CDS YP_002738660.1 225857149 7681187 complement(1429621..1430787) 1 NC_012467.1 identified by match to protein family HMM PF00155; putative aminotransferase B 1430787 7681187 SPP_1544 Streptococcus pneumoniae P1031 putative aminotransferase B YP_002738660.1 1429621 R 488223 CDS YP_002738661.1 225857150 7682551 complement(1430795..1431889) 1 NC_012467.1 catalyzes the formation of cystathionine from L-cysteine and O-succinyl-L-homoserine; cystathionine gamma-synthase 1431889 7682551 SPP_1545 Streptococcus pneumoniae P1031 cystathionine gamma-synthase YP_002738661.1 1430795 R 488223 CDS YP_002738662.1 225857151 7681691 complement(1432047..1432769) 1 NC_012467.1 identified by match to protein family HMM PF00005; ABC transporter 1432769 7681691 SPP_1546 Streptococcus pneumoniae P1031 ABC transporter YP_002738662.1 1432047 R 488223 CDS YP_002738663.1 225857152 7682805 1432929..1434275 1 NC_012467.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop; identified by match to protein family HMM PF01609; Spn1 transposase 1434275 7682805 SPP_1547 Streptococcus pneumoniae P1031 Spn1 transposase YP_002738663.1 1432929 D 488223 CDS YP_002738664.1 225857153 7681370 complement(1435609..1437567) 1 NC_012467.1 identified by match to protein family HMM PF00496; oligopeptide binding lipoprotein 1437567 7681370 SPP_1550 Streptococcus pneumoniae P1031 oligopeptide binding lipoprotein YP_002738664.1 1435609 R 488223 CDS YP_002738665.1 225857154 7680927 complement(1437770..1439407) 1 NC_012467.1 identified by match to protein family HMM PF01943; match to protein family HMM PF03023; polysaccharide transporter 1439407 7680927 SPP_1551 Streptococcus pneumoniae P1031 polysaccharide transporter YP_002738665.1 1437770 R 488223 CDS YP_002738666.1 225857155 7682256 1439498..1440943 1 NC_012467.1 involved in cell wall formation; peptidoglycan synthesis; cytoplasmic enzyme; catalyzes the addition of lysine to UDP-N-acetylmuramoyl-L-alanyl-D-glutamate forming UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysine; UDP-N-acetylmuramoylalanyl-D-glutamate--L-lysine ligase 1440943 7682256 SPP_1552 Streptococcus pneumoniae P1031 UDP-N-acetylmuramoylalanyl-D-glutamate--L-lysine ligase YP_002738666.1 1439498 D 488223 CDS YP_002738667.1 225857156 7681997 complement(1440989..1441183) 1 NC_012467.1 identified by match to protein family HMM PF05532; hypothetical protein 1441183 7681997 SPP_1553 Streptococcus pneumoniae P1031 hypothetical protein YP_002738667.1 1440989 R 488223 CDS YP_002738668.1 225857157 7681182 complement(1441284..1441568) 1 NC_012467.1 identified by glimmer; putative; hypothetical protein 1441568 7681182 SPP_1554 Streptococcus pneumoniae P1031 hypothetical protein YP_002738668.1 1441284 R 488223 CDS YP_002738669.1 225857158 7681681 complement(1441565..1441879) 1 NC_012467.1 identified by glimmer; putative; hypothetical protein 1441879 7681681 SPP_1555 Streptococcus pneumoniae P1031 hypothetical protein YP_002738669.1 1441565 R 488223 CDS YP_002738670.1 225857159 7681424 complement(1441916..1442428) 1 NC_012467.1 hypothetical protein 1442428 7681424 SPP_1556 Streptococcus pneumoniae P1031 hypothetical protein YP_002738670.1 1441916 R 488223 CDS YP_002738671.1 225857160 7681850 complement(1442514..1443449) 1 NC_012467.1 catalyzes the hydrolysis of pyrophosphate to phosphate; putative manganese-dependent inorganic pyrophosphatase 1443449 7681850 SPP_1557 Streptococcus pneumoniae P1031 putative manganese-dependent inorganic pyrophosphatase YP_002738671.1 1442514 R 488223 CDS YP_002738672.1 225857161 7681734 complement(1443520..1443819) 1 NC_012467.1 identified by match to protein family HMM PF01541; hypothetical protein 1443819 7681734 SPP_1558 Streptococcus pneumoniae P1031 hypothetical protein YP_002738672.1 1443520 R 488223 CDS YP_002738673.1 225857162 7682117 complement(1443809..1444558) 1 NC_012467.1 identified by match to protein family HMM PF05175; methyltransferase 1444558 7682117 SPP_1559 Streptococcus pneumoniae P1031 methyltransferase YP_002738673.1 1443809 R 488223 CDS YP_002738674.1 225857163 7681784 complement(1444612..1444998) 1 NC_012467.1 identified by match to protein family HMM PF00575; hypothetical protein 1444998 7681784 SPP_1560 Streptococcus pneumoniae P1031 hypothetical protein YP_002738674.1 1444612 R 488223 CDS YP_002738675.1 225857164 7682374 complement(1444973..1446373) 1 NC_012467.1 identified by match to protein family HMM PF00160; match to protein family HMM PF00702; match to protein family HMM PF05116; match to protein family HMM PF08282; match to protein family HMM TIGR00099; match to protein family HMM TIGR01484; Cof family protein/peptidyl-prolyl cis-trans isomerase, cyclophilin type 1446373 7682374 SPP_1561 Streptococcus pneumoniae P1031 Cof family protein/peptidyl-prolyl cis-trans isomerase, cyclophilin type YP_002738675.1 1444973 R 488223 CDS YP_002738676.1 225857165 7681928 complement(1446668..1446907) 1 NC_012467.1 binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit; 30S ribosomal protein S18 1446907 rpsR 7681928 rpsR Streptococcus pneumoniae P1031 30S ribosomal protein S18 YP_002738676.1 1446668 R 488223 CDS YP_002738677.1 225857166 7681431 complement(1446939..1447409) 1 NC_012467.1 binds to single stranded DNA and may facilitate the binding and interaction of other proteins to DNA; single-stranded DNA-binding protein 1447409 7681431 SPP_1563 Streptococcus pneumoniae P1031 single-stranded DNA-binding protein YP_002738677.1 1446939 R 488223 CDS YP_002738678.1 225857167 7681560 complement(1447421..1447711) 1 NC_012467.1 binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21; 30S ribosomal protein S6 1447711 rpsF 7681560 rpsF Streptococcus pneumoniae P1031 30S ribosomal protein S6 YP_002738678.1 1447421 R 488223 CDS YP_002738679.1 225857168 7682711 complement(1447864..1449207) 1 NC_012467.1 catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; asparaginyl-tRNA synthetase 1449207 asnC 7682711 asnC Streptococcus pneumoniae P1031 asparaginyl-tRNA synthetase YP_002738679.1 1447864 R 488223 CDS YP_002738680.1 225857169 7682795 complement(1449226..1449591) 1 NC_012467.1 identified by match to protein family HMM PF00903; glyoxalase family protein 1449591 7682795 SPP_1566 Streptococcus pneumoniae P1031 glyoxalase family protein YP_002738680.1 1449226 R 488223 CDS YP_002738681.1 225857170 7681854 complement(1449584..1450771) 1 NC_012467.1 catalyzes the formation of oxalozcetate and L-glutamate from L-aspartate and 2-oxoglutarate; aspartate aminotransferase 1450771 7681854 SPP_1567 Streptococcus pneumoniae P1031 aspartate aminotransferase YP_002738681.1 1449584 R 488223 CDS YP_002738682.1 225857171 7681261 complement(1450768..1451256) 1 NC_012467.1 identified by match to protein family HMM PF03413; peptidase propeptide and ypeb domain protein 1451256 7681261 SPP_1568 Streptococcus pneumoniae P1031 peptidase propeptide and ypeb domain protein YP_002738682.1 1450768 R 488223 CDS YP_002738683.1 225857172 7682612 complement(1451323..1451439) 1 NC_012467.1 identified by glimmer; putative; hypothetical protein 1451439 7682612 SPP_1569 Streptococcus pneumoniae P1031 hypothetical protein YP_002738683.1 1451323 R 488223 CDS YP_002738684.1 225857173 7681816 1451577..1452125 1 NC_012467.1 identified by match to protein family HMM PF02525; match to protein family HMM PF03358; oxidoreductase 1452125 7681816 SPP_1570 Streptococcus pneumoniae P1031 oxidoreductase YP_002738684.1 1451577 D 488223 CDS YP_002738685.1 225857174 7682740 complement(1452402..1453130) 1 NC_012467.1 identified by match to protein family HMM PF03883; hypothetical protein 1453130 7682740 SPP_1571 Streptococcus pneumoniae P1031 hypothetical protein YP_002738685.1 1452402 R 488223 CDS YP_002738686.1 225857175 7681103 complement(1453209..1453373) 1 NC_012467.1 hypothetical protein 1453373 7681103 SPP_1572 Streptococcus pneumoniae P1031 hypothetical protein YP_002738686.1 1453209 R 488223 CDS YP_002738687.1 225857176 7682194 complement(1453440..1455035) 1 NC_012467.1 hypothetical protein 1455035 7682194 SPP_1573 Streptococcus pneumoniae P1031 hypothetical protein YP_002738687.1 1453440 R 488223 CDS YP_002738688.1 225857177 7682190 complement(1455047..1455457) 1 NC_012467.1 cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+); peptide deformylase 1455457 def2 7682190 def2 Streptococcus pneumoniae P1031 peptide deformylase YP_002738688.1 1455047 R 488223 CDS YP_002738689.1 225857178 7682811 complement(1455573..1456364) 1 NC_012467.1 YghU; B2989; one of eight putative glutathione transferase proteins from E. coli; putative glutathione S-transferase YghU 1456364 7682811 SPP_1575 Streptococcus pneumoniae P1031 putative glutathione S-transferase YghU YP_002738689.1 1455573 R 488223 CDS YP_002738690.1 225857179 7682599 complement(1456377..1459073) 1 NC_012467.1 identified by match to protein family HMM PF00122; match to protein family HMM PF00689; match to protein family HMM PF00690; match to protein family HMM PF00702; match to protein family HMM TIGR01494; calcium-transporting ATPase 1 1459073 7682599 SPP_1576 Streptococcus pneumoniae P1031 calcium-transporting ATPase 1 YP_002738690.1 1456377 R 488223 CDS YP_002738691.1 225857180 7681518 1459377..1460561 1 NC_012467.1 identified by match to protein family HMM PF01545; match to protein family HMM TIGR01297; cation efflux family protein 1460561 7681518 SPP_1577 Streptococcus pneumoniae P1031 cation efflux family protein YP_002738691.1 1459377 D 488223 CDS YP_002738692.1 225857181 7681856 complement(1460704..1462575) 1 NC_012467.1 identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 1462575 7681856 SPP_1578 Streptococcus pneumoniae P1031 ABC transporter ATP-binding protein YP_002738692.1 1460704 R 488223 CDS YP_002738693.1 225857182 7681069 complement(1462572..1463756) 1 NC_012467.1 catalyzes the addition and repair of the 3'-terminal CCA sequence in tRNA; these proteins belong to the CCA-adding enzyme subfamily 2 which does not have phosphohydrolase activity; tRNA CCA-pyrophosphorylase 1463756 7681069 SPP_1579 Streptococcus pneumoniae P1031 tRNA CCA-pyrophosphorylase YP_002738693.1 1462572 R 488223 CDS YP_002738694.1 225857183 7682094 complement(1463768..1464535) 1 NC_012467.1 catalyzes the reduction of 2,3-dihydrodipicolinate to 2,3,4,5-tetrahydrodipicolinate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate reductase 1464535 dapB 7682094 dapB Streptococcus pneumoniae P1031 dihydrodipicolinate reductase YP_002738694.1 1463768 R 488223 CDS YP_002738695.1 225857184 7682701 complement(1464812..1465660) 1 NC_012467.1 identified by match to protein family HMM PF02645; match to protein family HMM TIGR00762; hypothetical protein 1465660 7682701 SPP_1581 Streptococcus pneumoniae P1031 hypothetical protein YP_002738695.1 1464812 R 488223 CDS YP_002738696.1 225857185 7681984 complement(1465662..1466036) 1 NC_012467.1 identified by match to protein family HMM PF06619; hypothetical protein 1466036 7681984 SPP_1582 Streptococcus pneumoniae P1031 hypothetical protein YP_002738696.1 1465662 R 488223 CDS YP_002738697.1 225857186 7681669 complement(1466110..1467462) 1 NC_012467.1 catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; phosphoglucosamine mutase 1467462 glmM 7681669 glmM Streptococcus pneumoniae P1031 phosphoglucosamine mutase YP_002738697.1 1466110 R 488223 CDS YP_002738698.1 225857187 7681058 complement(1467486..1468265) 1 NC_012467.1 identified by match to protein family HMM PF07949; lipoprotein, putative 1468265 7681058 SPP_1584 Streptococcus pneumoniae P1031 lipoprotein, putative YP_002738698.1 1467486 R 488223 CDS YP_002738699.1 225857188 7682404 complement(1468252..1469109) 1 NC_012467.1 identified by match to protein family HMM PF02457; match to protein family HMM TIGR00159; hypothetical protein 1469109 7682404 SPP_1585 Streptococcus pneumoniae P1031 hypothetical protein YP_002738699.1 1468252 R 488223 CDS YP_002738700.1 225857189 7681840 1469245..1470213 1 NC_012467.1 identified by match to protein family HMM PF00070; match to protein family HMM PF03486; match to protein family HMM PF07992; thioredoxin reductase 1470213 7681840 SPP_1586 Streptococcus pneumoniae P1031 thioredoxin reductase YP_002738700.1 1469245 D 488223 CDS YP_002738701.1 225857190 7681632 complement(1470247..1471158) 1 NC_012467.1 identified by match to protein family HMM PF02650; match to protein family HMM TIGR00647; hypothetical protein 1471158 7681632 SPP_1587 Streptococcus pneumoniae P1031 hypothetical protein YP_002738701.1 1470247 R 488223 CDS YP_002738702.1 225857191 7681294 complement(1471155..1472132) 1 NC_012467.1 identified by match to protein family HMM PF01933; match to protein family HMM TIGR01826; transporter 1472132 7681294 SPP_1588 Streptococcus pneumoniae P1031 transporter YP_002738702.1 1471155 R 488223 CDS YP_002738703.1 225857192 7682391 complement(1472129..1473019) 1 NC_012467.1 identified by match to protein family HMM PF03668; hypothetical protein 1473019 7682391 SPP_1589 Streptococcus pneumoniae P1031 hypothetical protein YP_002738703.1 1472129 R 488223 CDS YP_002738704.1 225857193 7682643 complement(1473071..1473451) 1 NC_012467.1 identified by match to protein family HMM PF01042; match to protein family HMM TIGR00004; endoribonuclease L-PSP, putative 1473451 7682643 SPP_1590 Streptococcus pneumoniae P1031 endoribonuclease L-PSP, putative YP_002738704.1 1473071 R 488223 CDS YP_002738705.1 225857194 7682126 complement(1473462..1474049) 1 NC_012467.1 binds guanine nucleotides; in Escherichia coli depletion results in defective cell division and filamentation; in Bacillus subtilis this gene is essential; ribosome biogenesis GTP-binding protein YsxC 1474049 engB 7682126 engB Streptococcus pneumoniae P1031 ribosome biogenesis GTP-binding protein YsxC YP_002738705.1 1473462 R 488223 CDS YP_002738706.1 225857195 7682172 complement(1474058..1475290) 1 NC_012467.1 binds and unfolds substrates as part of the ClpXP protease; ATP-dependent protease ATP-binding subunit ClpX 1475290 clpX 7682172 clpX Streptococcus pneumoniae P1031 ATP-dependent protease ATP-binding subunit ClpX YP_002738706.1 1474058 R 488223 CDS YP_002738707.1 225857196 7682828 complement(1475322..1475492) 1 NC_012467.1 hypothetical protein 1475492 7682828 SPP_1593 Streptococcus pneumoniae P1031 hypothetical protein YP_002738707.1 1475322 R 488223 CDS YP_002738708.1 225857197 7681426 complement(1475492..1475998) 1 NC_012467.1 identified by match to protein family HMM PF00186; dihydrofolate reductase 1475998 folA 7681426 folA Streptococcus pneumoniae P1031 dihydrofolate reductase YP_002738708.1 1475492 R 488223 CDS YP_002738709.1 225857198 7681202 complement(1476128..1476646) 1 NC_012467.1 identified by match to protein family HMM PF00210; DNA protection during starvation protein 1476646 7681202 SPP_1595 Streptococcus pneumoniae P1031 DNA protection during starvation protein YP_002738709.1 1476128 R 488223 CDS YP_002738710.1 225857199 7682016 complement(1477143..1478615) 1 NC_012467.1 identified by match to protein family HMM PF01183; match to protein family HMM PF01473; 1,4-beta-N-acetylmuramidase 1478615 7682016 SPP_1596 Streptococcus pneumoniae P1031 1,4-beta-N-acetylmuramidase YP_002738710.1 1477143 R 488223 CDS YP_002738711.1 225857200 7681001 complement(1478686..1479444) 1 NC_012467.1 Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate; triosephosphate isomerase 1479444 tpiA 7681001 tpiA Streptococcus pneumoniae P1031 triosephosphate isomerase YP_002738711.1 1478686 R 488223 CDS YP_002738712.1 225857201 7681595 complement(1479542..1480219) 1 NC_012467.1 identified by match to protein family HMM PF04271; match to protein family HMM TIGR01446; DNA replication protein DnaD 1480219 7681595 SPP_1598 Streptococcus pneumoniae P1031 DNA replication protein DnaD YP_002738712.1 1479542 R 488223 CDS YP_002738713.1 225857202 7681832 complement(1480228..1481172) 1 NC_012467.1 catalyzes the formation of O-succinyl-L-homoserine from succinyl-CoA and L-homoserine in methionine biosynthesis; homoserine O-succinyltransferase 1481172 metA 7681832 metA Streptococcus pneumoniae P1031 homoserine O-succinyltransferase YP_002738713.1 1480228 R 488223 CDS YP_002738714.1 225857203 7681645 complement(1481354..1481866) 1 NC_012467.1 catalyzes a salvage reaction resulting in the formation of AMP which is metabolically less costly than a de novo synthesis; adenine phosphoribosyltransferase 1481866 apt 7681645 apt Streptococcus pneumoniae P1031 adenine phosphoribosyltransferase YP_002738714.1 1481354 R 488223 CDS YP_002738715.1 225857204 7681682 complement(1481953..1482711) 1 NC_012467.1 identified by match to protein family HMM PF08241; match to protein family HMM PF08242; SAM-dependent methyltransferase 1482711 7681682 SPP_1601 Streptococcus pneumoniae P1031 SAM-dependent methyltransferase YP_002738715.1 1481953 R 488223 CDS YP_002738716.1 225857205 7681249 1482919..1483065 1 NC_012467.1 chlorohydrolase 1483065 7681249 SPP_1602 Streptococcus pneumoniae P1031 chlorohydrolase YP_002738716.1 1482919 D 488223 CDS YP_002738717.1 225857206 7682007 complement(1483212..1484342) 1 NC_012467.1 identified by match to protein family HMM PF00005; match to protein family HMM PF03459; match to protein family HMM PF08402; multiple sugar-binding transport ATP-binding protein MsmK 1484342 7682007 SPP_1603 Streptococcus pneumoniae P1031 multiple sugar-binding transport ATP-binding protein MsmK YP_002738717.1 1483212 R 488223 CDS YP_002738718.1 225857207 7680734 complement(1484792..1485367) 1 NC_012467.1 identified by match to protein family HMM PF00857; isochorismatase 1485367 7680734 SPP_1605 Streptococcus pneumoniae P1031 isochorismatase YP_002738718.1 1484792 R 488223 CDS YP_002738719.1 225857208 7681757 complement(1485367..1486155) 1 NC_012467.1 CodY; DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase (By similarity). It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor; transcriptional repressor CodY 1486155 codY 7681757 codY Streptococcus pneumoniae P1031 transcriptional repressor CodY YP_002738719.1 1485367 R 488223 CDS YP_002738720.1 225857209 7682520 complement(1486420..1487994) 1 NC_012467.1 identified by match to protein family HMM PF00270; match to protein family HMM PF00271; cold-shock DEAD box protein A 1487994 7682520 SPP_1607 Streptococcus pneumoniae P1031 cold-shock DEAD box protein A YP_002738720.1 1486420 R 488223 CDS YP_002738721.1 225857210 7682056 complement(1488193..1489419) 1 NC_012467.1 identified by match to protein family HMM PF07690; major facilitator:Oxalate:Formate Antiporter 1489419 7682056 SPP_1608 Streptococcus pneumoniae P1031 major facilitator:Oxalate:Formate Antiporter YP_002738721.1 1488193 R 488223 CDS YP_002738722.1 225857211 7681020 1489613..1490929 1 NC_012467.1 Involved in disulfide oxidoreductase activity and electron transport; pyridine nucleotide-disulfide oxidoreductase 1490929 7681020 SPP_1609 Streptococcus pneumoniae P1031 pyridine nucleotide-disulfide oxidoreductase YP_002738722.1 1489613 D 488223 CDS YP_002738723.1 225857212 7682298 1491028..1492371 1 NC_012467.1 identified by match to protein family HMM PF08245; match to protein family HMM PF08353; Mur ligase family protein 1492371 7682298 SPP_1610 Streptococcus pneumoniae P1031 Mur ligase family protein YP_002738723.1 1491028 D 488223 CDS YP_002738724.1 225857213 7682576 1492371..1493153 1 NC_012467.1 identified by match to protein family HMM PF07685; cobyric acid synthase 1493153 7682576 SPP_1611 Streptococcus pneumoniae P1031 cobyric acid synthase YP_002738724.1 1492371 D 488223 CDS YP_002738725.1 225857214 7681195 1493279..1494361 1 NC_012467.1 identified by match to protein family HMM PF00557; match to protein family HMM PF01321; Xaa-Pro dipeptidase (X-Pro dipeptidase) (Prolinedipeptidase) (Prolidase) (Imidodipeptidase) 1494361 7681195 SPP_1612 Streptococcus pneumoniae P1031 Xaa-Pro dipeptidase (X-Pro dipeptidase) (Prolinedipeptidase) (Prolidase) (Imidodipeptidase) YP_002738725.1 1493279 D 488223 CDS YP_002738726.1 225857215 7681055 1494354..1494557 1 NC_012467.1 hypothetical protein 1494557 7681055 SPP_1613 Streptococcus pneumoniae P1031 hypothetical protein YP_002738726.1 1494354 D 488223 CDS YP_002738727.1 225857216 7682115 complement(1494682..1494900) 1 NC_012467.1 transposase OrfB 1494900 7682115 SPP_1614 Streptococcus pneumoniae P1031 transposase OrfB YP_002738727.1 1494682 R 488223 CDS YP_002738728.1 225857217 7681435 1495576..1495764 1 NC_012467.1 identified by glimmer; putative; hypothetical protein 1495764 7681435 SPP_1617 Streptococcus pneumoniae P1031 hypothetical protein YP_002738728.1 1495576 D 488223 CDS YP_002738729.1 225857218 7682563 complement(1495757..1496218) 1 NC_012467.1 hypothetical protein 1496218 7682563 SPP_1616 Streptococcus pneumoniae P1031 hypothetical protein YP_002738729.1 1495757 R 488223 CDS YP_002738730.1 225857219 7681099 complement(1496196..1496969) 1 NC_012467.1 catalyzes the formation of 4-amino-2-methyl-5-diphosphomethylpyrimidine; phosphomethylpyrimidine kinase 1496969 7681099 SPP_1618 Streptococcus pneumoniae P1031 phosphomethylpyrimidine kinase YP_002738730.1 1496196 R 488223 CDS YP_002738731.1 225857220 7681465 complement(1496959..1497708) 1 NC_012467.1 mediates pseudouridylation (positions 38, 39, 40) at the tRNA anticodon region which contributes to the structural stability; tRNA pseudouridine synthase A 1497708 truA 7681465 truA Streptococcus pneumoniae P1031 tRNA pseudouridine synthase A YP_002738731.1 1496959 R 488223 CDS YP_002738732.1 225857221 7681804 complement(1498026..1499177) 1 NC_012467.1 identified by match to protein family HMM PF07690; major facilitator superfamily transporter 1499177 7681804 SPP_1620 Streptococcus pneumoniae P1031 major facilitator superfamily transporter YP_002738732.1 1498026 R 488223 CDS YP_002738733.1 225857222 7680960 1499149..1499265 1 NC_012467.1 identified by glimmer; putative; hypothetical protein 1499265 7680960 SPP_1621 Streptococcus pneumoniae P1031 hypothetical protein YP_002738733.1 1499149 D 488223 CDS YP_002738734.1 225857223 7681440 complement(1499417..1500046) 1 NC_012467.1 hypothetical protein 1500046 7681440 SPP_1622 Streptococcus pneumoniae P1031 hypothetical protein YP_002738734.1 1499417 R 488223 CDS YP_002738735.1 225857224 7680995 complement(1500049..1500387) 1 NC_012467.1 identified by match to protein family HMM PF03831; match to protein family HMM PF08274; match to protein family HMM TIGR00686; alkylphosphonate utilization operon protein PhnA 1500387 phnA 7680995 phnA Streptococcus pneumoniae P1031 alkylphosphonate utilization operon protein PhnA YP_002738735.1 1500049 R 488223 CDS YP_002738736.1 225857225 7682032 complement(1500518..1501189) 1 NC_012467.1 Catalyzes the formation of (d)CDP from ATP and (d)CMP; cytidylate kinase 1501189 cmk 7682032 cmk Streptococcus pneumoniae P1031 cytidylate kinase YP_002738736.1 1500518 R 488223 CDS YP_002738737.1 225857226 7682082 complement(1501198..1501674) 1 NC_012467.1 hypothetical protein 1501674 7682082 SPP_1625 Streptococcus pneumoniae P1031 hypothetical protein YP_002738737.1 1501198 R 488223 CDS YP_002738738.1 225857227 7682521 1501816..1501932 1 NC_012467.1 ferredoxin 1501932 7682521 SPP_1626 Streptococcus pneumoniae P1031 ferredoxin YP_002738738.1 1501816 D 488223 CDS YP_002738739.1 225857228 7682432 complement(1501994..1502947) 1 NC_012467.1 identified by match to protein family HMM PF00535; bactoprenol glucosyl transferase 1502947 7682432 SPP_1627 Streptococcus pneumoniae P1031 bactoprenol glucosyl transferase YP_002738739.1 1501994 R 488223 CDS YP_002738740.1 225857229 7681911 complement(1502949..1503968) 1 NC_012467.1 identified by match to protein family HMM PF00106; match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF04321; match to protein family HMM PF07993; match to protein family HMM TIGR01179; UDP-glucose 4-epimerase 1503968 galE2 7681911 galE2 Streptococcus pneumoniae P1031 UDP-glucose 4-epimerase YP_002738740.1 1502949 R 488223 CDS YP_002738741.1 225857230 7681389 complement(1504071..1504262) 1 NC_012467.1 identified by glimmer; putative; hypothetical protein 1504262 7681389 SPP_1629 Streptococcus pneumoniae P1031 hypothetical protein YP_002738741.1 1504071 R 488223 CDS YP_002738742.1 225857231 7681066 complement(1504269..1505372) 1 NC_012467.1 identified by match to protein family HMM PF01266; FAD dependent oxidoreductase 1505372 7681066 SPP_1630 Streptococcus pneumoniae P1031 FAD dependent oxidoreductase YP_002738742.1 1504269 R 488223 CDS YP_002738743.1 225857232 7682137 complement(1505389..1506186) 1 NC_012467.1 identified by match to protein family HMM PF01784; match to protein family HMM TIGR00486; hypothetical protein 1506186 7682137 SPP_1631 Streptococcus pneumoniae P1031 hypothetical protein YP_002738743.1 1505389 R 488223 CDS YP_002738744.1 225857233 7680694 complement(1506173..1506850) 1 NC_012467.1 identified by match to protein family HMM PF04816; Bcl-2 family protein 1506850 7680694 SPP_1632 Streptococcus pneumoniae P1031 Bcl-2 family protein YP_002738744.1 1506173 R 488223 CDS YP_002738745.1 225857234 7681445 1507400..1508392 1 NC_012467.1 hypothetical protein 1508392 7681445 SPP_1633 Streptococcus pneumoniae P1031 hypothetical protein YP_002738745.1 1507400 D 488223 CDS YP_002738746.1 225857235 7681319 complement(1509071..1509727) 1 NC_012467.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; transposase 1509727 7681319 SPP_1636 Streptococcus pneumoniae P1031 transposase YP_002738746.1 1509071 R 488223 CDS YP_002738747.1 225857236 7680705 complement(1510100..1512070) 1 NC_012467.1 catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase; transketolase 1512070 tkt1 7680705 tkt1 Streptococcus pneumoniae P1031 transketolase YP_002738747.1 1510100 R 488223 CDS YP_002738748.1 225857237 7680899 complement(1512107..1512802) 1 NC_012467.1 identified by match to protein family HMM PF00834; allulose-6-phosphate 3-epimerase 1512802 7680899 SPP_1638 Streptococcus pneumoniae P1031 allulose-6-phosphate 3-epimerase YP_002738748.1 1512107 R 488223 CDS YP_002738749.1 225857238 7682565 complement(1512813..1513898) 1 NC_012467.1 identified by match to protein family HMM PF02378; match to protein family HMM TIGR01427; PTS system, IIC component 1513898 7682565 SPP_1639 Streptococcus pneumoniae P1031 PTS system, IIC component YP_002738749.1 1512813 R 488223 CDS YP_002738750.1 225857239 7682797 complement(1514263..1514712) 1 NC_012467.1 identified by match to protein family HMM PF00359; match to protein family HMM TIGR00848; PTS system, IIA component 1514712 7682797 SPP_1641 Streptococcus pneumoniae P1031 PTS system, IIA component YP_002738750.1 1514263 R 488223 CDS YP_002738751.1 225857240 7681273 complement(1514690..1515118) 1 NC_012467.1 identified by match to protein family HMM PF00359; PTS system, nitrogen regulatory component IIA, putative 1515118 7681273 SPP_1642 Streptococcus pneumoniae P1031 PTS system, nitrogen regulatory component IIA, putative YP_002738751.1 1514690 R 488223 CDS YP_002738752.1 225857241 7681700 complement(1515111..1516574) 1 NC_012467.1 identified by match to protein family HMM PF00874; match to protein family HMM PF05043; match to protein family HMM PF08279; putative transcription antiterminator BglG family protein 1516574 7681700 SPP_1643 Streptococcus pneumoniae P1031 putative transcription antiterminator BglG family protein YP_002738752.1 1515111 R 488223 CDS YP_002738753.1 225857242 7682098 complement(1517103..1519439) 1 NC_012467.1 identified by match to protein family HMM PF00122; match to protein family HMM PF00702; match to protein family HMM TIGR01494; P-type ATPase - metal cation transport 1519439 7682098 SPP_1644 Streptococcus pneumoniae P1031 P-type ATPase - metal cation transport YP_002738753.1 1517103 R 488223 CDS YP_002738754.1 225857243 7682660 1519572..1520321 1 NC_012467.1 identified by match to protein family HMM PF01553; acyltransferase family protein 1520321 7682660 SPP_1645 Streptococcus pneumoniae P1031 acyltransferase family protein YP_002738754.1 1519572 D 488223 CDS YP_002738755.1 225857244 7680983 complement(1520614..1521228) 1 NC_012467.1 identified by match to protein family HMM PF03596; match to protein family HMM TIGR00779; CadD 1521228 7680983 SPP_1646 Streptococcus pneumoniae P1031 CadD YP_002738755.1 1520614 R 488223 CDS YP_002738756.1 225857245 7681896 complement(1522044..1522313) 1 NC_012467.1 primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence; 30S ribosomal protein S15 1522313 rpsO 7681896 rpsO Streptococcus pneumoniae P1031 30S ribosomal protein S15 YP_002738756.1 1522044 R 488223 CDS YP_002738757.1 225857246 7681579 complement(1522454..1523083) 1 NC_012467.1 YwnB 1523083 7681579 SPP_1648 Streptococcus pneumoniae P1031 YwnB YP_002738757.1 1522454 R 488223 CDS YP_002738758.1 225857247 7681306 1523942..1524265 1 NC_012467.1 hypothetical protein 1524265 7681306 SPP_1649 Streptococcus pneumoniae P1031 hypothetical protein YP_002738758.1 1523942 D 488223 CDS YP_002738759.1 225857248 7681679 1524323..1526266 1 NC_012467.1 catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr); threonyl-tRNA synthetase 1526266 thrS 7681679 thrS Streptococcus pneumoniae P1031 threonyl-tRNA synthetase YP_002738759.1 1524323 D 488223 CDS YP_002738760.1 225857249 7681625 complement(1526315..1527289) 1 NC_012467.1 identified by match to protein family HMM PF02518; histidine kinase 1527289 7681625 SPP_1651 Streptococcus pneumoniae P1031 histidine kinase YP_002738760.1 1526315 R 488223 CDS YP_002738761.1 225857250 7681901 complement(1527282..1527959) 1 NC_012467.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00486; response regulator 1527959 7681901 SPP_1652 Streptococcus pneumoniae P1031 response regulator YP_002738761.1 1527282 R 488223 CDS YP_002738762.1 225857251 7682519 1528115..1529188 1 NC_012467.1 hypothetical protein 1529188 7682519 SPP_1653 Streptococcus pneumoniae P1031 hypothetical protein YP_002738762.1 1528115 D 488223 CDS YP_002738763.1 225857252 7682737 complement(1529279..1529581) 1 NC_012467.1 hypothetical protein 1529581 7682737 SPP_1654 Streptococcus pneumoniae P1031 hypothetical protein YP_002738763.1 1529279 R 488223 CDS YP_002738764.1 225857253 7682050 complement(1529649..1530086) 1 NC_012467.1 identified by match to protein family HMM PF02082; Rrf2 family protein 1530086 7682050 SPP_1655 Streptococcus pneumoniae P1031 Rrf2 family protein YP_002738764.1 1529649 R 488223 CDS YP_002738765.1 225857254 7680856 complement(1530162..1531004) 1 NC_012467.1 identified by match to protein family HMM PF00149; metallophosphoesterase 1531004 7680856 SPP_1656 Streptococcus pneumoniae P1031 metallophosphoesterase YP_002738765.1 1530162 R 488223 CDS YP_002738766.1 225857255 7681942 1531116..1531766 1 NC_012467.1 identified by match to protein family HMM PF01047; match to protein family HMM PF01325; match to protein family HMM PF02742; match to protein family HMM PF04023; iron-dependent transcriptional regulator 1531766 7681942 SPP_1657 Streptococcus pneumoniae P1031 iron-dependent transcriptional regulator YP_002738766.1 1531116 D 488223 CDS YP_002738767.1 225857256 7682431 1531747..1531938 1 NC_012467.1 hypothetical protein 1531938 7682431 SPP_1658 Streptococcus pneumoniae P1031 hypothetical protein YP_002738767.1 1531747 D 488223 CDS YP_002738768.1 225857257 7680681 1531964..1532611 1 NC_012467.1 hypothetical protein 1532611 7680681 SPP_1659 Streptococcus pneumoniae P1031 hypothetical protein YP_002738768.1 1531964 D 488223 CDS YP_002738769.1 225857258 7682109 1532742..1533155 1 NC_012467.1 hypothetical protein 1533155 7682109 SPP_1660 Streptococcus pneumoniae P1031 hypothetical protein YP_002738769.1 1532742 D 488223 CDS YP_002738770.1 225857259 7680910 1533174..1533359 1 NC_012467.1 hypothetical protein 1533359 7680910 SPP_1661 Streptococcus pneumoniae P1031 hypothetical protein YP_002738770.1 1533174 D 488223 CDS YP_002738771.1 225857260 7681623 1533426..1533587 1 NC_012467.1 identified by glimmer; putative; hypothetical protein 1533587 7681623 SPP_1662 Streptococcus pneumoniae P1031 hypothetical protein YP_002738771.1 1533426 D 488223 CDS YP_002738772.1 225857261 7680781 complement(1533626..1534069) 1 NC_012467.1 hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr); possible defense mechanism against a harmful effect of D-tyrosine; D-tyrosyl-tRNA(Tyr) deacylase 1534069 dtd 7680781 dtd Streptococcus pneumoniae P1031 D-tyrosyl-tRNA(Tyr) deacylase YP_002738772.1 1533626 R 488223 CDS YP_002738773.1 225857262 7680929 complement(1534099..1536321) 1 NC_012467.1 identified by match to protein family HMM PF01966; match to protein family HMM PF02824; match to protein family HMM PF04607; match to protein family HMM TIGR00691; guanosine-3,5-bis(diphosphate) 3-pyrophosphohydrolase 1536321 spoT 7680929 spoT Streptococcus pneumoniae P1031 guanosine-3,5-bis(diphosphate) 3-pyrophosphohydrolase YP_002738773.1 1534099 R 488223 CDS YP_002738774.1 225857263 7681677 1537317..1537946 1 NC_012467.1 identified by match to protein family HMM PF00753; metallo-beta-lactamase superfamily protein 1537946 7681677 SPP_1665 Streptococcus pneumoniae P1031 metallo-beta-lactamase superfamily protein YP_002738774.1 1537317 D 488223 CDS YP_002738775.1 225857264 7682681 complement(1538069..1539961) 1 NC_012467.1 identified by match to protein family HMM PF01431; match to protein family HMM PF05649; endopeptidase O 1539961 7682681 SPP_1666 Streptococcus pneumoniae P1031 endopeptidase O YP_002738775.1 1538069 R 488223 CDS YP_002738776.1 225857265 7682139 1540252..1540974 1 NC_012467.1 identified by match to protein family HMM PF00005; manganese transport system ATP-binding protein MntA 1540974 7682139 SPP_1667 Streptococcus pneumoniae P1031 manganese transport system ATP-binding protein MntA YP_002738776.1 1540252 D 488223 CDS YP_002738777.1 225857266 7681696 1540971..1541819 1 NC_012467.1 identified by match to protein family HMM PF00950; manganese transport system membrane protein MntB 1541819 7681696 SPP_1668 Streptococcus pneumoniae P1031 manganese transport system membrane protein MntB YP_002738777.1 1540971 D 488223 CDS YP_002738778.1 225857267 7682807 1541851..1542780 1 NC_012467.1 identified by match to protein family HMM PF01297; manganese ABC transporter substrate-binding lipoprotein (Adhesin B) (Saliva-binding protein) 1542780 7682807 SPP_1669 Streptococcus pneumoniae P1031 manganese ABC transporter substrate-binding lipoprotein (Adhesin B) (Saliva-binding protein) YP_002738778.1 1541851 D 488223 CDS YP_002738779.1 225857268 7681671 1542903..1543394 1 NC_012467.1 antioxidant activity; thioredoxin-dependent thiol peroxidase; forms homodimers in solution; shows substrate specificity to alkyl hydroperoxides; periplasmic protein; thiol peroxidase 1543394 tpx 7681671 tpx Streptococcus pneumoniae P1031 thiol peroxidase YP_002738779.1 1542903 D 488223 CDS YP_002738780.1 225857269 7681415 complement(1543490..1546198) 1 NC_012467.1 identified by match to protein family HMM PF02687; efflux ABC transporter, permease protein 1546198 7681415 SPP_1671 Streptococcus pneumoniae P1031 efflux ABC transporter, permease protein YP_002738780.1 1543490 R 488223 CDS YP_002738781.1 225857270 7681831 complement(1546200..1546901) 1 NC_012467.1 identified by match to protein family HMM PF00005; macrolide export ATP-binding/permease protein MacB 1546901 7681831 SPP_1672 Streptococcus pneumoniae P1031 macrolide export ATP-binding/permease protein MacB YP_002738781.1 1546200 R 488223 CDS YP_002738782.1 225857271 7682463 complement(1547151..1549562) 1 NC_012467.1 alpha-fucosidase 1549562 7682463 SPP_1673 Streptococcus pneumoniae P1031 alpha-fucosidase YP_002738782.1 1547151 R 488223 CDS YP_002738783.1 225857272 7681540 complement(1549615..1550307) 1 NC_012467.1 2,3-bisphosphoglycerate-dependent; catalyzes the interconversion of 2-phosphoglycerate to 3-phosphoglycerate; phosphoglyceromutase 1550307 gpmA 7681540 gpmA Streptococcus pneumoniae P1031 phosphoglyceromutase YP_002738783.1 1549615 R 488223 CDS YP_002738784.1 225857273 7681658 complement(1550358..1550648) 1 NC_012467.1 hypothetical protein 1550648 7681658 SPP_1675 Streptococcus pneumoniae P1031 hypothetical protein YP_002738784.1 1550358 R 488223 CDS YP_002738785.1 225857274 7682275 complement(1550842..1551222) 1 NC_012467.1 prophage Lp1 protein 6 1551222 7682275 SPP_1676 Streptococcus pneumoniae P1031 prophage Lp1 protein 6 YP_002738785.1 1550842 R 488223 CDS YP_002738786.1 225857275 7682709 complement(1551625..1554417) 1 NC_012467.1 IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase family type 1 subfamily; some organisms carry two different copies of this enzyme; isoleucyl-tRNA synthetase 1554417 ileS 7682709 ileS Streptococcus pneumoniae P1031 isoleucyl-tRNA synthetase YP_002738786.1 1551625 R 488223 CDS YP_002738787.1 225857276 7681209 complement(1554670..1554786) 1 NC_012467.1 hypothetical protein 1554786 7681209 SPP_1678 Streptococcus pneumoniae P1031 hypothetical protein YP_002738787.1 1554670 R 488223 CDS YP_002738788.1 225857277 7682537 complement(1554765..1555553) 1 NC_012467.1 identified by match to protein family HMM PF05103; cell-division initiation protein 1555553 7682537 SPP_1679 Streptococcus pneumoniae P1031 cell-division initiation protein YP_002738788.1 1554765 R 488223 CDS YP_002738789.1 225857278 7681542 complement(1555562..1556347) 1 NC_012467.1 identified by match to protein family HMM PF01479; YlmH protein 1556347 7681542 SPP_1680 Streptococcus pneumoniae P1031 YlmH protein YP_002738789.1 1555562 R 488223 CDS YP_002738790.1 225857279 7680635 complement(1556344..1556607) 1 NC_012467.1 identified by match to protein family HMM PF02325; yggt family, putative 1556607 7680635 SPP_1681 Streptococcus pneumoniae P1031 yggt family, putative YP_002738790.1 1556344 R 488223 CDS YP_002738791.1 225857280 7682271 complement(1556607..1557146) 1 NC_012467.1 identified by match to protein family HMM PF04472; YlmF protein 1557146 7682271 SPP_1682 Streptococcus pneumoniae P1031 YlmF protein YP_002738791.1 1556607 R 488223 CDS YP_002738792.1 225857281 7681709 complement(1557156..1557827) 1 NC_012467.1 identified by match to protein family HMM TIGR00044; pyridoxal phosphate enzyme, YggS family 1557827 7681709 SPP_1683 Streptococcus pneumoniae P1031 pyridoxal phosphate enzyme, YggS family YP_002738792.1 1557156 R 488223 CDS YP_002738793.1 225857282 7680897 complement(1557832..1559091) 1 NC_012467.1 GTPase; similar structure to tubulin; forms ring-shaped polymers at the site of cell division; other proteins such as FtsA, ZipA, and ZapA, interact with and regulate FtsZ function; cell division protein FtsZ 1559091 ftsZ 7680897 ftsZ Streptococcus pneumoniae P1031 cell division protein FtsZ YP_002738793.1 1557832 R 488223 CDS YP_002738794.1 225857283 7680802 complement(1559108..1560481) 1 NC_012467.1 identified by match to protein family HMM PF02491; match to protein family HMM TIGR01174; cell division protein FtsA 1560481 ftsA 7680802 ftsA Streptococcus pneumoniae P1031 cell division protein FtsA YP_002738794.1 1559108 R 488223 CDS YP_002738795.1 225857284 7681468 complement(1560700..1561404) 1 NC_012467.1 identified by match to protein family HMM TIGR02206; hypothetical protein 1561404 7681468 SPP_1686 Streptococcus pneumoniae P1031 hypothetical protein YP_002738795.1 1560700 R 488223 CDS YP_002738796.1 225857285 7681650 complement(1561495..1562106) 1 NC_012467.1 identified by match to protein family HMM PF00293; MutT/nudix family protein 1562106 7681650 SPP_1687 Streptococcus pneumoniae P1031 MutT/nudix family protein YP_002738796.1 1561495 R 488223 CDS YP_002738797.1 225857286 7681005 complement(1562093..1563466) 1 NC_012467.1 identified by match to protein family HMM PF01225; match to protein family HMM PF02875; match to protein family HMM PF08245; match to protein family HMM TIGR01143; UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate--D-alanyl-D-alanyl ligase 1563466 7681005 SPP_1688 Streptococcus pneumoniae P1031 UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate--D-alanyl-D-alanyl ligase YP_002738797.1 1562093 R 488223 CDS YP_002738798.1 225857287 7682307 complement(1563550..1564593) 1 NC_012467.1 D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli; D-alanyl-alanine synthetase A 1564593 ddl 7682307 ddl Streptococcus pneumoniae P1031 D-alanyl-alanine synthetase A YP_002738798.1 1563550 R 488223 CDS YP_002738799.1 225857288 7681830 complement(1564788..1565384) 1 NC_012467.1 involved in a recombinational process of DNA repair, independent of the recBC complex; recombination protein RecR 1565384 recR 7681830 recR Streptococcus pneumoniae P1031 recombination protein RecR YP_002738799.1 1564788 R 488223 CDS YP_002738800.1 225857289 7681355 complement(1565395..1567437) 1 NC_012467.1 identified by match to protein family HMM PF00905; match to protein family HMM PF03717; penicillin-binding protein 2B 1567437 7681355 SPP_1691 Streptococcus pneumoniae P1031 penicillin-binding protein 2B YP_002738800.1 1565395 R 488223 CDS YP_002738801.1 225857290 7681037 1567652..1568503 1 NC_012467.1 identified by match to protein family HMM PF01380; match to protein family HMM PF01418; transcriptional regulator, RpiR family 1568503 7681037 SPP_1692 Streptococcus pneumoniae P1031 transcriptional regulator, RpiR family YP_002738801.1 1567652 D 488223 CDS YP_002738802.1 225857291 7682429 complement(1568519..1569403) 1 NC_012467.1 identified by match to protein family HMM PF00480; glucokinase 1569403 7682429 SPP_1693 Streptococcus pneumoniae P1031 glucokinase YP_002738802.1 1568519 R 488223 CDS YP_002738803.1 225857292 7682327 complement(1569421..1570338) 1 NC_012467.1 identified by match to protein family HMM PF00701; N-acetylneuraminate lyase 1570338 7682327 SPP_1694 Streptococcus pneumoniae P1031 N-acetylneuraminate lyase YP_002738803.1 1569421 R 488223 CDS YP_002738804.1 225857293 7681673 complement(1570507..1571151) 1 NC_012467.1 identified by match to protein family HMM PF04854; hypothetical protein 1571151 7681673 SPP_1695 Streptococcus pneumoniae P1031 hypothetical protein YP_002738804.1 1570507 R 488223 CDS YP_002738805.1 225857294 7681106 1571499..1571651 1 NC_012467.1 identified by glimmer; putative; hypothetical protein 1571651 7681106 SPP_1696 Streptococcus pneumoniae P1031 hypothetical protein YP_002738805.1 1571499 D 488223 CDS YP_002738806.1 225857295 7682609 complement(1571876..1572328) 1 NC_012467.1 identified by match to protein family HMM PF04074; match to protein family HMM TIGR00022; hypothetical protein 1572328 7682609 SPP_1697 Streptococcus pneumoniae P1031 hypothetical protein YP_002738806.1 1571876 R 488223 CDS YP_002738807.1 225857296 7680915 complement(1572600..1573439) 1 NC_012467.1 identified by match to protein family HMM PF00528; sugar ABC transporter permease 1573439 7680915 SPP_1698 Streptococcus pneumoniae P1031 sugar ABC transporter permease YP_002738807.1 1572600 R 488223 CDS YP_002738808.1 225857297 7682160 complement(1573455..1574342) 1 NC_012467.1 identified by match to protein family HMM PF00528; sugar ABC transporter permease 1574342 7682160 SPP_1699 Streptococcus pneumoniae P1031 sugar ABC transporter permease YP_002738808.1 1573455 R 488223 CDS YP_002738809.1 225857298 7682821 complement(1574574..1575902) 1 NC_012467.1 identified by match to protein family HMM PF01547; sugar ABC transporter substrate-binding protein 1575902 7682821 SPP_1700 Streptococcus pneumoniae P1031 sugar ABC transporter substrate-binding protein YP_002738809.1 1574574 R 488223 CDS YP_002738810.1 225857299 7682184 complement(1576027..1577544) 1 NC_012467.1 identified by match to protein family HMM PF00367; match to protein family HMM PF02378; match to protein family HMM TIGR00826; pts system maltose- and glucose-specific eiicb component 1577544 7682184 SPP_1701 Streptococcus pneumoniae P1031 pts system maltose- and glucose-specific eiicb component YP_002738810.1 1576027 R 488223 CDS YP_002738811.1 225857300 7682674 complement(1577563..1578261) 1 NC_012467.1 Converts N-acetylmannosamine-6-phosphate to N-acetylglucosamine-6-phosphate; N-acetylmannosamine-6-phosphate 2-epimerase 1578261 7682674 SPP_1702 Streptococcus pneumoniae P1031 N-acetylmannosamine-6-phosphate 2-epimerase YP_002738811.1 1577563 R 488223 CDS YP_002738812.1 225857301 7682607 complement(1578434..1579537) 1 NC_012467.1 identified by match to protein family HMM PF01118; match to protein family HMM PF01408; match to protein family HMM PF02894; match to protein family HMM PF03447; putative oxidoreductase YjhC 1579537 7682607 SPP_1703 Streptococcus pneumoniae P1031 putative oxidoreductase YjhC YP_002738812.1 1578434 R 488223 CDS YP_002738813.1 225857302 7682492 complement(1579549..1581642) 1 NC_012467.1 identified by match to protein family HMM PF02012; match to protein family HMM PF02973; sialidase B (Neuraminidase B) 1581642 7682492 SPP_1704 Streptococcus pneumoniae P1031 sialidase B (Neuraminidase B) YP_002738813.1 1579549 R 488223 CDS YP_002738814.1 225857303 7681571 complement(1581660..1582493) 1 NC_012467.1 identified by match to protein family HMM PF00528; ABC transporter permease 1582493 7681571 SPP_1705 Streptococcus pneumoniae P1031 ABC transporter permease YP_002738814.1 1581660 R 488223 CDS YP_002738815.1 225857304 7680634 complement(1582493..1583377) 1 NC_012467.1 identified by match to protein family HMM PF00528; ABC transporter permease 1583377 7680634 SPP_1706 Streptococcus pneumoniae P1031 ABC transporter permease YP_002738815.1 1582493 R 488223 CDS YP_002738816.1 225857305 7682833 complement(1583456..1584793) 1 NC_012467.1 identified by match to protein family HMM PF01547; sugar ABC transporter substrate-binding protein 1584793 7682833 SPP_1707 Streptococcus pneumoniae P1031 sugar ABC transporter substrate-binding protein YP_002738816.1 1583456 R 488223 CDS YP_002738817.1 225857306 7681383 complement(1584812..1585264) 1 NC_012467.1 identified by match to protein family HMM PF04074; match to protein family HMM TIGR00022; hypothetical protein 1585264 7681383 SPP_1708 Streptococcus pneumoniae P1031 hypothetical protein YP_002738817.1 1584812 R 488223 CDS YP_002738818.1 225857307 7681102 complement(1586277..1589345) 1 NC_012467.1 identified by match to protein family HMM PF02012; match to protein family HMM PF02973; match to protein family HMM TIGR01167; neuraminidase 1589345 7681102 SPP_1709 Streptococcus pneumoniae P1031 neuraminidase YP_002738818.1 1586277 R 488223 CDS YP_002738819.1 225857308 7680869 complement(1589702..1589929) 1 NC_012467.1 hypothetical protein 1589929 7680869 SPP_1710 Streptococcus pneumoniae P1031 hypothetical protein YP_002738819.1 1589702 R 488223 CDS YP_002738820.1 225857309 7680800 complement(1591049..1592029) 1 NC_012467.1 identified by match to protein family HMM PF05448; xylan esterase 1 1592029 7680800 SPP_1712 Streptococcus pneumoniae P1031 xylan esterase 1 YP_002738820.1 1591049 R 488223 CDS YP_002738821.1 225857310 7682482 complement(1592345..1594360) 1 NC_012467.1 catalyzes branch migration in Holliday junction intermediates; ATP-dependent DNA helicase RecG 1594360 recG 7682482 recG Streptococcus pneumoniae P1031 ATP-dependent DNA helicase RecG YP_002738821.1 1592345 R 488223 CDS YP_002738822.1 225857311 7682858 complement(1594379..1595482) 1 NC_012467.1 converts L-alanine to D-alanine which is used in cell wall biosynthesis; binds one pyridoxal phosphate per monomer; forms a homodimer; alanine racemase 1595482 alr 7682858 alr Streptococcus pneumoniae P1031 alanine racemase YP_002738822.1 1594379 R 488223 CDS YP_002738823.1 225857312 7682209 complement(1595472..1595834) 1 NC_012467.1 Catalyzes the formation of holo-ACP, which mediates the essential transfer of acyl fatty acid intermediates during the biosynthesis of fatty acids and lipids; 4'-phosphopantetheinyl transferase 1595834 acpS 7682209 acpS Streptococcus pneumoniae P1031 4'-phosphopantetheinyl transferase YP_002738823.1 1595472 R 488223 CDS YP_002738824.1 225857313 7682529 complement(1595879..1596910) 1 NC_012467.1 catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, phenylalanine sensitive; phospho-2-dehydro-3-deoxyheptonate aldolase 1596910 7682529 SPP_1716 Streptococcus pneumoniae P1031 phospho-2-dehydro-3-deoxyheptonate aldolase YP_002738824.1 1595879 R 488223 CDS YP_002738825.1 225857314 7681473 complement(1596912..1597943) 1 NC_012467.1 catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, tyrosine sensitive; phospho-2-dehydro-3-deoxyheptonate aldolase 1597943 7681473 SPP_1717 Streptococcus pneumoniae P1031 phospho-2-dehydro-3-deoxyheptonate aldolase YP_002738825.1 1596912 R 488223 CDS YP_002738826.1 225857315 7680940 complement(1598024..1600537) 1 NC_012467.1 functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond SecA1; SecA2 is not essential and seems to play a role in secretion of a subset of proteins; preprotein translocase subunit SecA 1600537 secA 7680940 secA Streptococcus pneumoniae P1031 preprotein translocase subunit SecA YP_002738826.1 1598024 R 488223 CDS YP_002738827.1 225857316 7681811 complement(1600683..1600796) 1 NC_012467.1 identified by glimmer; putative; hypothetical protein 1600796 7681811 SPP_1719 Streptococcus pneumoniae P1031 hypothetical protein YP_002738827.1 1600683 R 488223 CDS YP_002738828.1 225857317 7681318 complement(1601000..1601632) 1 NC_012467.1 identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 1601632 7681318 SPP_1720 Streptococcus pneumoniae P1031 ABC transporter ATP-binding protein YP_002738828.1 1601000 R 488223 CDS YP_002738829.1 225857318 7682076 complement(1601636..1602211) 1 NC_012467.1 hypothetical protein 1602211 7682076 SPP_1721 Streptococcus pneumoniae P1031 hypothetical protein YP_002738829.1 1601636 R 488223 CDS YP_002738830.1 225857319 7682680 complement(1602270..1603061) 1 NC_012467.1 hypothetical protein 1603061 7682680 SPP_1722 Streptococcus pneumoniae P1031 hypothetical protein YP_002738830.1 1602270 R 488223 CDS YP_002738831.1 225857320 7681060 complement(1603246..1603581) 1 NC_012467.1 hypothetical protein 1603581 7681060 SPP_1723 Streptococcus pneumoniae P1031 hypothetical protein YP_002738831.1 1603246 R 488223 CDS YP_002738832.1 225857321 7681362 complement(1603721..1604059) 1 NC_012467.1 hypothetical protein 1604059 7681362 SPP_1724 Streptococcus pneumoniae P1031 hypothetical protein YP_002738832.1 1603721 R 488223 CDS YP_002738833.1 225857322 7681631 complement(1604147..1605457) 1 NC_012467.1 EngA; essential Neisserial GTPase; synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains; GTP-binding protein EngA 1605457 engA 7681631 engA Streptococcus pneumoniae P1031 GTP-binding protein EngA YP_002738833.1 1604147 R 488223 CDS YP_002738834.1 225857323 7682619 complement(1605471..1606184) 1 NC_012467.1 identified by match to protein family HMM PF00881; nitroreductase family protein 1606184 7682619 SPP_1726 Streptococcus pneumoniae P1031 nitroreductase family protein YP_002738834.1 1605471 R 488223 CDS YP_002738835.1 225857324 7682078 complement(1606181..1607077) 1 NC_012467.1 Primosomal protein that may act to load helicase DnaC during DNA replication; primosomal protein DnaI 1607077 7682078 SPP_1727 Streptococcus pneumoniae P1031 primosomal protein DnaI YP_002738835.1 1606181 R 488223 CDS YP_002738836.1 225857325 7681987 complement(1607078..1608247) 1 NC_012467.1 identified by match to protein family HMM PF07261; replication initiation and membrane attachment protein 1608247 7681987 SPP_1728 Streptococcus pneumoniae P1031 replication initiation and membrane attachment protein YP_002738836.1 1607078 R 488223 CDS YP_002738837.1 225857326 7682412 complement(1608248..1608721) 1 NC_012467.1 identified by match to protein family HMM PF03477; match to protein family HMM TIGR00244; transcriptional regulator NrdR 1608721 nrdR 7682412 nrdR Streptococcus pneumoniae P1031 transcriptional regulator NrdR YP_002738837.1 1608248 R 488223 CDS YP_002738838.1 225857327 7682389 1608861..1609226 1 NC_012467.1 identified by match to protein family HMM PF00392; GntR family transcriptional regulator 1609226 7682389 SPP_1730 Streptococcus pneumoniae P1031 GntR family transcriptional regulator YP_002738838.1 1608861 D 488223 CDS YP_002738839.1 225857328 7681455 1609231..1609926 1 NC_012467.1 identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 1609926 7681455 SPP_1731 Streptococcus pneumoniae P1031 ABC transporter ATP-binding protein YP_002738839.1 1609231 D 488223 CDS YP_002738840.1 225857329 7681521 1609943..1610710 1 NC_012467.1 hypothetical protein 1610710 7681521 SPP_1732 Streptococcus pneumoniae P1031 hypothetical protein YP_002738840.1 1609943 D 488223 CDS YP_002738841.1 225857330 7680913 complement(1611063..1612262) 1 NC_012467.1 Na+ ABC transporter permease 1612262 7680913 SPP_1733 Streptococcus pneumoniae P1031 Na+ ABC transporter permease YP_002738841.1 1611063 R 488223 CDS YP_002738842.1 225857331 7682322 complement(1612259..1613152) 1 NC_012467.1 identified by match to protein family HMM PF00005; Na+ ABC transporter ATP-binding protein 1613152 7682322 SPP_1734 Streptococcus pneumoniae P1031 Na+ ABC transporter ATP-binding protein YP_002738842.1 1612259 R 488223 CDS YP_002738843.1 225857332 7681912 1613275..1613646 1 NC_012467.1 hypothetical protein 1613646 7681912 SPP_1735 Streptococcus pneumoniae P1031 hypothetical protein YP_002738843.1 1613275 D 488223 CDS YP_002738844.1 225857333 7680837 1614642..1615259 1 NC_012467.1 identified by match to protein family HMM PF09335; hypothetical protein 1615259 7680837 SPP_1736 Streptococcus pneumoniae P1031 hypothetical protein YP_002738844.1 1614642 D 488223 CDS YP_002738845.1 225857334 7682192 complement(1615302..1616189) 1 NC_012467.1 identified by match to protein family HMM PF00480; fructokinase 1616189 7682192 SPP_1737 Streptococcus pneumoniae P1031 fructokinase YP_002738845.1 1615302 R 488223 CDS YP_002738846.1 225857335 7682768 complement(1616338..1618221) 1 NC_012467.1 identified by match to protein family HMM PF00358; match to protein family HMM PF00367; match to protein family HMM PF02378; match to protein family HMM TIGR00826; match to protein family HMM TIGR00830; match to protein family HMM TIGR01996; pts system, sucrose-specific iibc component 1618221 7682768 SPP_1738 Streptococcus pneumoniae P1031 pts system, sucrose-specific iibc component YP_002738846.1 1616338 R 488223 CDS YP_002738847.1 225857336 7680989 complement(1618347..1618544) 1 NC_012467.1 hypothetical protein 1618544 7680989 SPP_1739 Streptococcus pneumoniae P1031 hypothetical protein YP_002738847.1 1618347 R 488223 CDS YP_002738848.1 225857337 7681630 1618597..1620051 1 NC_012467.1 identified by match to protein family HMM PF00251; match to protein family HMM PF08244; match to protein family HMM TIGR01322; sucrose-6-phosphate hydrolase (Sucrase) (Invertase) 1620051 7681630 SPP_1740 Streptococcus pneumoniae P1031 sucrose-6-phosphate hydrolase (Sucrase) (Invertase) YP_002738848.1 1618597 D 488223 CDS YP_002738849.1 225857338 7681821 1620032..1620997 1 NC_012467.1 identified by match to protein family HMM PF00356; match to protein family HMM PF00532; sucrose operon repressor (Scr operon regulatory protein) 1620997 7681821 SPP_1741 Streptococcus pneumoniae P1031 sucrose operon repressor (Scr operon regulatory protein) YP_002738849.1 1620032 D 488223 CDS YP_002738850.1 225857339 7680858 complement(1622307..1623503) 1 NC_012467.1 identified by match to protein family HMM PF01154; match to protein family HMM PF08540; match to protein family HMM TIGR01835; hydroxymethylglutaryl-CoA synthase 1623503 7680858 SPP_1744 Streptococcus pneumoniae P1031 hydroxymethylglutaryl-CoA synthase YP_002738850.1 1622307 R 488223 CDS YP_002738851.1 225857340 7682636 complement(1623610..1623858) 1 NC_012467.1 hypothetical protein 1623858 7682636 SPP_1745 Streptococcus pneumoniae P1031 hypothetical protein YP_002738851.1 1623610 R 488223 CDS YP_002738852.1 225857341 7682063 complement(1623926..1624315) 1 NC_012467.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by match to protein family HMM PF01609; transposase (IS4 family) 1624315 7682063 SPP_1746 Streptococcus pneumoniae P1031 transposase (IS4 family) YP_002738852.1 1623926 R 488223 CDS YP_002738853.1 225857342 7681506 complement(1624332..1624547) 1 NC_012467.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; mobile genetic element 1624547 7681506 SPP_1747 Streptococcus pneumoniae P1031 mobile genetic element YP_002738853.1 1624332 R 488223 CDS YP_002738854.1 225857343 7682210 complement(1624612..1625061) 1 NC_012467.1 hypothetical protein 1625061 7682210 SPP_1748 Streptococcus pneumoniae P1031 hypothetical protein YP_002738854.1 1624612 R 488223 CDS YP_002738855.1 225857344 7680942 complement(1625063..1625821) 1 NC_012467.1 identified by match to protein family HMM PF06738; hypothetical protein 1625821 7680942 SPP_1749 Streptococcus pneumoniae P1031 hypothetical protein YP_002738855.1 1625063 R 488223 CDS YP_002738856.1 225857345 7681371 complement(1625936..1627915) 1 NC_012467.1 identified by match to protein family HMM PF00069; match to protein family HMM PF01163; match to protein family HMM PF03793; Stk1 1627915 7681371 SPP_1750 Streptococcus pneumoniae P1031 Stk1 YP_002738856.1 1625936 R 488223 CDS YP_002738857.1 225857346 7682227 complement(1627912..1628652) 1 NC_012467.1 identified by match to protein family HMM PF00481; protein phosphatase PrpC 1628652 7682227 SPP_1751 Streptococcus pneumoniae P1031 protein phosphatase PrpC YP_002738857.1 1627912 R 488223 CDS YP_002738858.1 225857347 7682513 complement(1628667..1629980) 1 NC_012467.1 identified by match to protein family HMM PF01029; match to protein family HMM PF01189; match to protein family HMM TIGR00563; ribosomal RNA small subunit methyltransferase B 1629980 sun 7682513 sun Streptococcus pneumoniae P1031 ribosomal RNA small subunit methyltransferase B YP_002738858.1 1628667 R 488223 CDS YP_002738859.1 225857348 7681181 complement(1629973..1630908) 1 NC_012467.1 modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet) which is important in translation initiation; inactivation of this gene in Escherichia coli severely impairs growth; methionyl-tRNA formyltransferase 1630908 fmt 7681181 fmt Streptococcus pneumoniae P1031 methionyl-tRNA formyltransferase YP_002738859.1 1629973 R 488223 CDS YP_002738860.1 225857349 7680685 complement(1630921..1633317) 1 NC_012467.1 binding of PriA to forked DNA starts the assembly of the primosome, also possesses 3'-5' helicase activity; primosome assembly protein PriA 1633317 7680685 SPP_1754 Streptococcus pneumoniae P1031 primosome assembly protein PriA YP_002738860.1 1630921 R 488223 CDS YP_002738861.1 225857350 7682813 complement(1633383..1633694) 1 NC_012467.1 Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits; DNA-directed RNA polymerase subunit omega 1633694 7682813 SPP_1755 Streptococcus pneumoniae P1031 DNA-directed RNA polymerase subunit omega YP_002738861.1 1633383 R 488223 CDS YP_002738862.1 225857351 7682277 complement(1633722..1634348) 1 NC_012467.1 Essential for recycling GMP and indirectly, cGMP; guanylate kinase 1634348 gmk 7682277 gmk Streptococcus pneumoniae P1031 guanylate kinase YP_002738862.1 1633722 R 488223 CDS YP_002738863.1 225857352 7681763 complement(1634478..1636091) 1 NC_012467.1 identified by match to protein family HMM PF00013; match to protein family HMM PF01966; match to protein family HMM TIGR00277; match to protein family HMM TIGR03319; hypothetical protein 1636091 7681763 SPP_1757 Streptococcus pneumoniae P1031 hypothetical protein YP_002738863.1 1634478 R 488223 CDS YP_002738864.1 225857353 7681548 complement(1636434..1639181) 1 NC_012467.1 hypothetical protein 1639181 7681548 SPP_1758 Streptococcus pneumoniae P1031 hypothetical protein YP_002738864.1 1636434 R 488223 CDS YP_002738865.1 225857354 7682461 complement(1639528..1640625) 1 NC_012467.1 identified by match to protein family HMM PF05636; hypothetical protein 1640625 7682461 SPP_1759 Streptococcus pneumoniae P1031 hypothetical protein YP_002738865.1 1639528 R 488223 CDS YP_002738866.1 225857355 7682546 complement(1640635..1641381) 1 NC_012467.1 identified by match to protein family HMM PF08241; match to protein family HMM PF08242; SAM-dependent methyltransferase 1641381 7682546 SPP_1760 Streptococcus pneumoniae P1031 SAM-dependent methyltransferase YP_002738866.1 1640635 R 488223 CDS YP_002738867.1 225857356 7682292 complement(1641484..1641837) 1 NC_012467.1 identified by match to protein family HMM PF02410; match to protein family HMM TIGR00090; putative iojap homolog 1641837 7682292 SPP_1761 Streptococcus pneumoniae P1031 putative iojap homolog YP_002738867.1 1641484 R 488223 CDS YP_002738868.1 225857357 7680629 complement(1641850..1642350) 1 NC_012467.1 identified by match to protein family HMM PF00857; isochorismatase family protein 1642350 7680629 SPP_1762 Streptococcus pneumoniae P1031 isochorismatase family protein YP_002738868.1 1641850 R 488223 CDS YP_002738869.1 225857358 7681552 complement(1642351..1642944) 1 NC_012467.1 identified by match to protein family HMM PF01966; match to protein family HMM TIGR00277; match to protein family HMM TIGR00488; hypothetical protein 1642944 7681552 SPP_1763 Streptococcus pneumoniae P1031 hypothetical protein YP_002738869.1 1642351 R 488223 CDS YP_002738870.1 225857359 7680967 complement(1642944..1643573) 1 NC_012467.1 transfers an adenyl group from ATP to NaMN to form nicotinic acid adenine dinucleotide (NaAD) which is then converted to the ubiquitous compound NAD by NAD synthetase; essential enzyme in bacteria; nicotinic acid mononucleotide adenylyltransferase 1643573 nadD 7680967 nadD Streptococcus pneumoniae P1031 nicotinic acid mononucleotide adenylyltransferase YP_002738870.1 1642944 R 488223 CDS YP_002738871.1 225857360 7681203 complement(1643625..1643936) 1 NC_012467.1 identified by match to protein family HMM PF01985; match to protein family HMM TIGR00253; hypothetical protein 1643936 7681203 SPP_1765 Streptococcus pneumoniae P1031 hypothetical protein YP_002738871.1 1643625 R 488223 CDS YP_002738872.1 225857361 7681228 complement(1644150..1645256) 1 NC_012467.1 in Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis; GTP-binding protein YqeH 1645256 7681228 SPP_1766 Streptococcus pneumoniae P1031 GTP-binding protein YqeH YP_002738872.1 1644150 R 488223 CDS YP_002738873.1 225857362 7681269 complement(1645259..1645786) 1 NC_012467.1 identified by match to protein family HMM TIGR01662; match to protein family HMM TIGR01668; had superfamily (subfamily iiia) phosphatase 1645786 yqeG 7681269 yqeG Streptococcus pneumoniae P1031 had superfamily (subfamily iiia) phosphatase YP_002738873.1 1645259 R 488223 CDS YP_002738874.1 225857363 7682590 complement(1645801..1646709) 1 NC_012467.1 identified by match to protein family HMM PF01544; CorA - magnesium and cobalt transporter 1646709 7682590 SPP_1768 Streptococcus pneumoniae P1031 CorA - magnesium and cobalt transporter YP_002738874.1 1645801 R 488223 CDS YP_002738875.1 225857364 7681096 complement(1646766..1647326) 1 NC_012467.1 identified by match to protein family HMM PF00924; small conductance mechanosensitive ion channel 1647326 7681096 SPP_1769 Streptococcus pneumoniae P1031 small conductance mechanosensitive ion channel YP_002738875.1 1646766 R 488223 CDS YP_002738876.1 225857365 7681906 1648741..1649694 1 NC_012467.1 identified by match to protein family HMM PF06081; integral membrane protein 1649694 7681906 SPP_1772 Streptococcus pneumoniae P1031 integral membrane protein YP_002738876.1 1648741 D 488223 CDS YP_002738877.1 225857366 7681959 1649837..1650217 1 NC_012467.1 identified by match to protein family HMM PF01047; transcriptional regulator, putative 1650217 7681959 SPP_1773 Streptococcus pneumoniae P1031 transcriptional regulator, putative YP_002738877.1 1649837 D 488223 CDS YP_002738878.1 225857367 7681085 1650316..1650537 1 NC_012467.1 hypothetical protein 1650537 7681085 SPP_1774 Streptococcus pneumoniae P1031 hypothetical protein YP_002738878.1 1650316 D 488223 CDS YP_002738879.1 225857368 7682159 1650554..1650868 1 NC_012467.1 identified by match to protein family HMM PF00085; match to protein family HMM TIGR01068; thioredoxin 1650868 trx 7682159 trx Streptococcus pneumoniae P1031 thioredoxin YP_002738879.1 1650554 D 488223 CDS YP_002738880.1 225857369 7681282 1651173..1651706 1 NC_012467.1 NADPH-dependent; catalyzes the reduction of 7-cyano-7-deazaguanine to 7-aminomethyl-7-deazaguanine in queuosine biosynthesis; 7-cyano-7-deazaguanine reductase 1651706 7681282 SPP_1776 Streptococcus pneumoniae P1031 7-cyano-7-deazaguanine reductase YP_002738880.1 1651173 D 488223 CDS YP_002738881.1 225857370 7682297 complement(1651960..1652628) 1 NC_012467.1 identified by match to protein family HMM PF00230; aquaporin Z - water channel protein 1652628 7682297 SPP_1777 Streptococcus pneumoniae P1031 aquaporin Z - water channel protein YP_002738881.1 1651960 R 488223 CDS YP_002738882.1 225857371 7682583 complement(1652739..1653530) 1 NC_012467.1 hypothetical protein 1653530 7682583 SPP_1778 Streptococcus pneumoniae P1031 hypothetical protein YP_002738882.1 1652739 R 488223 CDS YP_002738883.1 225857372 7681325 complement(1653954..1654718) 1 NC_012467.1 identified by match to protein family HMM PF01061; ABC transporter 1654718 7681325 SPP_1779 Streptococcus pneumoniae P1031 ABC transporter YP_002738883.1 1653954 R 488223 CDS YP_002738884.1 225857373 7682012 complement(1654711..1655481) 1 NC_012467.1 identified by match to protein family HMM PF00005; Nod factor export ATP-binding protein I (Nodulation ATP-binding protein I) 1655481 7682012 SPP_1780 Streptococcus pneumoniae P1031 Nod factor export ATP-binding protein I (Nodulation ATP-binding protein I) YP_002738884.1 1654711 R 488223 CDS YP_002738885.1 225857374 7681022 1655728..1656405 1 NC_012467.1 identified by match to protein family HMM PF01022; transcriptional regulator, ArsR family 1656405 7681022 SPP_1781 Streptococcus pneumoniae P1031 transcriptional regulator, ArsR family YP_002738885.1 1655728 D 488223 CDS YP_002738886.1 225857375 7681138 complement(1656465..1658261) 1 NC_012467.1 identified by match to protein family HMM PF01432; match to protein family HMM PF08439; match to protein family HMM TIGR00181; oligoendopeptidase F 1658261 pepF2 7681138 pepF2 Streptococcus pneumoniae P1031 oligoendopeptidase F YP_002738886.1 1656465 R 488223 CDS YP_002738887.1 225857376 7682229 complement(1658272..1659015) 1 NC_012467.1 in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA; cells lacking this function can grow, but are outcompeted by wild-type; SAM-dependent m(3)U1498 methyltransferase; 16S ribosomal RNA methyltransferase RsmE 1659015 7682229 SPP_1783 Streptococcus pneumoniae P1031 16S ribosomal RNA methyltransferase RsmE YP_002738887.1 1658272 R 488223 CDS YP_002738888.1 225857377 7681110 complement(1659017..1659967) 1 NC_012467.1 methylates ribosomal protein L11 at multiple amino acid positions; mutations of these genes in Escherichia coli or Thermus thermophilus has no apparent phenotype; ribosomal protein L11 methyltransferase 1659967 prmA 7681110 prmA Streptococcus pneumoniae P1031 ribosomal protein L11 methyltransferase YP_002738888.1 1659017 R 488223 CDS YP_002738889.1 225857378 7682187 complement(1660105..1660533) 1 NC_012467.1 identified by match to protein family HMM PF00293; MutT/nudix family protein 1660533 7682187 SPP_1785 Streptococcus pneumoniae P1031 MutT/nudix family protein YP_002738889.1 1660105 R 488223 CDS YP_002738890.1 225857379 7682824 complement(1660514..1661602) 1 NC_012467.1 identified by match to protein family HMM PF02163; peptidase, M50 family protein 1661602 7682824 SPP_1786 Streptococcus pneumoniae P1031 peptidase, M50 family protein YP_002738890.1 1660514 R 488223 CDS YP_002738891.1 225857380 7682614 complement(1661621..1662091) 1 NC_012467.1 hypothetical protein 1662091 7682614 SPP_1787 Streptococcus pneumoniae P1031 hypothetical protein YP_002738891.1 1661621 R 488223 CDS YP_002738892.1 225857381 7681573 complement(1662382..1662834) 1 NC_012467.1 identified by match to protein family HMM PF03681; hypothetical protein 1662834 7681573 SPP_1788 Streptococcus pneumoniae P1031 hypothetical protein YP_002738892.1 1662382 R 488223 CDS YP_002738893.1 225857382 7681191 complement(1663186..1663365) 1 NC_012467.1 hypothetical protein 1663365 7681191 SPP_1789 Streptococcus pneumoniae P1031 hypothetical protein YP_002738893.1 1663186 R 488223 CDS YP_002738894.1 225857383 7681401 complement(1663530..1663769) 1 NC_012467.1 hypothetical protein 1663769 7681401 SPP_1790 Streptococcus pneumoniae P1031 hypothetical protein YP_002738894.1 1663530 R 488223 CDS YP_002738895.1 225857384 7680832 1664039..1665310 1 NC_012467.1 identified by match to protein family HMM PF00004; recombination factor protein RarA 1665310 7680832 SPP_1791 Streptococcus pneumoniae P1031 recombination factor protein RarA YP_002738895.1 1664039 D 488223 CDS YP_002738896.1 225857385 7680759 complement(1665857..1667176) 1 NC_012467.1 identified by match to protein family HMM PF00251; match to protein family HMM TIGR01322; sucrose-6-phosphate hydrolase 1667176 7680759 SPP_1793 Streptococcus pneumoniae P1031 sucrose-6-phosphate hydrolase YP_002738896.1 1665857 R 488223 CDS YP_002738897.1 225857386 7680828 complement(1667186..1668031) 1 NC_012467.1 identified by match to protein family HMM PF00528; sugar ABC transporter permease 1668031 7680828 SPP_1794 Streptococcus pneumoniae P1031 sugar ABC transporter permease YP_002738897.1 1667186 R 488223 CDS YP_002738898.1 225857387 7681910 complement(1668033..1668935) 1 NC_012467.1 identified by match to protein family HMM PF00528; ABC transporter permease 1668935 7681910 SPP_1795 Streptococcus pneumoniae P1031 ABC transporter permease YP_002738898.1 1668033 R 488223 CDS YP_002738899.1 225857388 7681582 complement(1669031..1670341) 1 NC_012467.1 identified by match to protein family HMM PF01547; sugar ABC transporter substrate-binding protein 1670341 7681582 SPP_1796 Streptococcus pneumoniae P1031 sugar ABC transporter substrate-binding protein YP_002738899.1 1669031 R 488223 CDS YP_002738900.1 225857389 7682223 complement(1670468..1671463) 1 NC_012467.1 identified by match to protein family HMM PF00356; match to protein family HMM PF00532; sugar-binding transcriptional regulator, LacI family protein 1671463 7682223 SPP_1797 Streptococcus pneumoniae P1031 sugar-binding transcriptional regulator, LacI family protein YP_002738900.1 1670468 R 488223 CDS YP_002738901.1 225857390 7681360 complement(1671825..1673306) 1 NC_012467.1 identified by match to protein family HMM PF05043; match to protein family HMM PF08270; match to protein family HMM PF08279; match to protein family HMM PF08280; M protein trans-acting positive transcriptional regulator 1673306 7681360 SPP_1798 Streptococcus pneumoniae P1031 M protein trans-acting positive transcriptional regulator YP_002738901.1 1671825 R 488223 CDS YP_002738902.1 225857391 7681052 1673749..1673913 1 NC_012467.1 identified by match to protein family HMM PF04226; hypothetical protein 1673913 7681052 SPP_1799 Streptococcus pneumoniae P1031 hypothetical protein YP_002738902.1 1673749 D 488223 CDS YP_002738903.1 225857392 7682695 1673997..1674563 1 NC_012467.1 hypothetical protein 1674563 7682695 SPP_1800 Streptococcus pneumoniae P1031 hypothetical protein YP_002738903.1 1673997 D 488223 CDS YP_002738904.1 225857393 7681592 1674575..1674745 1 NC_012467.1 lipoprotein, putative 1674745 7681592 SPP_1801 Streptococcus pneumoniae P1031 lipoprotein, putative YP_002738904.1 1674575 D 488223 CDS YP_002738905.1 225857394 7681880 1674784..1675392 1 NC_012467.1 identified by match to protein family HMM PF03780; Gls24 protein 1675392 7681880 SPP_1802 Streptococcus pneumoniae P1031 Gls24 protein YP_002738905.1 1674784 D 488223 CDS YP_002738906.1 225857395 7681171 1675423..1675626 1 NC_012467.1 identified by match to protein family HMM PF05532; hypothetical protein 1675626 7681171 SPP_1803 Streptococcus pneumoniae P1031 hypothetical protein YP_002738906.1 1675423 D 488223 CDS YP_002738907.1 225857396 7681281 complement(1676440..1676559) 1 NC_012467.1 identified by glimmer; putative; hypothetical protein 1676559 7681281 SPP_1804 Streptococcus pneumoniae P1031 hypothetical protein YP_002738907.1 1676440 R 488223 CDS YP_002738908.1 225857397 7681253 complement(1676777..1677484) 1 NC_012467.1 identified by match to protein family HMM PF01925; hypothetical protein 1677484 7681253 SPP_1805 Streptococcus pneumoniae P1031 hypothetical protein YP_002738908.1 1676777 R 488223 CDS YP_002738909.1 225857398 7681295 complement(1677562..1678008) 1 NC_012467.1 identified by match to protein family HMM PF03781; sulfatase-modifying factor 1 (C-alpha-formyglycine-generating enzyme 1) 1678008 7681295 SPP_1806 Streptococcus pneumoniae P1031 sulfatase-modifying factor 1 (C-alpha-formyglycine-generating enzyme 1) YP_002738909.1 1677562 R 488223 CDS YP_002738910.1 225857399 7681923 complement(1678094..1678696) 1 NC_012467.1 phosphotransferase system 1678696 7681923 SPP_1807 Streptococcus pneumoniae P1031 phosphotransferase system YP_002738910.1 1678094 R 488223 CDS YP_002738911.1 225857400 7681551 complement(1679039..1679356) 1 NC_012467.1 identified by match to protein family HMM PF02302; lichenan-specific phosphotransferase enzyme iib component (pts system lichenan-specific eiib component) (eiib-lic) 1679356 7681551 SPP_1810 Streptococcus pneumoniae P1031 lichenan-specific phosphotransferase enzyme iib component (pts system lichenan-specific eiib component) (eiib-lic) YP_002738911.1 1679039 R 488223 CDS YP_002738912.1 225857401 7680963 complement(1679371..1680267) 1 NC_012467.1 hypothetical protein 1680267 7680963 SPP_1811 Streptococcus pneumoniae P1031 hypothetical protein YP_002738912.1 1679371 R 488223 CDS YP_002738913.1 225857402 7680891 complement(1680270..1681532) 1 NC_012467.1 identified by match to protein family HMM PF02378; match to protein family HMM TIGR00410; lichenan permease iic component (pts system lichenan-specific eiiccomponent) (eiic-lic) 1681532 7680891 SPP_1812 Streptococcus pneumoniae P1031 lichenan permease iic component (pts system lichenan-specific eiiccomponent) (eiic-lic) YP_002738913.1 1680270 R 488223 CDS YP_002738914.1 225857403 7682371 1681812..1682990 1 NC_012467.1 identified by match to protein family HMM PF00480; ROK family protein, putative 1682990 7682371 SPP_1813 Streptococcus pneumoniae P1031 ROK family protein, putative YP_002738914.1 1681812 D 488223 CDS YP_002738915.1 225857404 7682874 complement(1683218..1683664) 1 NC_012467.1 identified by match to protein family HMM PF00583; acetyltransferase, gnat family 1683664 7682874 SPP_1814 Streptococcus pneumoniae P1031 acetyltransferase, gnat family YP_002738915.1 1683218 R 488223 CDS YP_002738916.1 225857405 7682134 1683734..1684393 1 NC_012467.1 identified by match to protein family HMM PF01478; match to protein family HMM PF06750; type 4 prepilin peptidase 1684393 7682134 SPP_1815 Streptococcus pneumoniae P1031 type 4 prepilin peptidase YP_002738916.1 1683734 D 488223 CDS YP_002738917.1 225857406 7682473 complement(1684445..1685596) 1 NC_012467.1 identified by match to protein family HMM PF01381; match to protein family HMM PF06114; transcriptional regulator 1685596 7682473 SPP_1816 Streptococcus pneumoniae P1031 transcriptional regulator YP_002738917.1 1684445 R 488223 CDS YP_002738918.1 225857407 7682757 complement(1685611..1686165) 1 NC_012467.1 identified by glimmer; putative; hypothetical protein 1686165 7682757 SPP_1817 Streptococcus pneumoniae P1031 hypothetical protein YP_002738918.1 1685611 R 488223 CDS YP_002738919.1 225857408 7681738 complement(1686202..1686342) 1 NC_012467.1 identified by glimmer; putative; hypothetical protein 1686342 7681738 SPP_1818 Streptococcus pneumoniae P1031 hypothetical protein YP_002738919.1 1686202 R 488223 CDS YP_002738920.1 225857409 7681408 complement(1686644..1687420) 1 NC_012467.1 catalyzes the formation of indole and glyceraldehyde 3-phosphate from indoleglycerol phosphate in tryptophan biosynthesis; tryptophan synthase subunit alpha 1687420 trpA 7681408 trpA Streptococcus pneumoniae P1031 tryptophan synthase subunit alpha YP_002738920.1 1686644 R 488223 CDS YP_002738921.1 225857410 7681559 complement(1687413..1688636) 1 NC_012467.1 catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate; tryptophan synthase subunit beta 1688636 trpB 7681559 trpB Streptococcus pneumoniae P1031 tryptophan synthase subunit beta YP_002738921.1 1687413 R 488223 CDS YP_002738922.1 225857411 7681918 complement(1688614..1689213) 1 NC_012467.1 catalyzes the formation of 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate from N-(5-phospho-beta-D-ribosyl)-anthranilate in tryptophan biosynthesis; N-(5'-phosphoribosyl)anthranilate isomerase 1689213 trpF 7681918 trpF Streptococcus pneumoniae P1031 N-(5'-phosphoribosyl)anthranilate isomerase YP_002738922.1 1688614 R 488223 CDS YP_002738923.1 225857412 7681262 complement(1689200..1689967) 1 NC_012467.1 involved in tryptophan biosynthesis; amino acid biosynthesis; converts 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate to C(1)-(3-indolyl)-glycerol 3-phosphate and carbon dioxide and water; indole-3-glycerol-phosphate synthase 1689967 trpC 7681262 trpC Streptococcus pneumoniae P1031 indole-3-glycerol-phosphate synthase YP_002738923.1 1689200 R 488223 CDS YP_002738924.1 225857413 7681270 complement(1689964..1690968) 1 NC_012467.1 Catalyzes the conversion of N-(5-phospho-D-ribosyl)-anthranilate and diphosphate to anthranilate and 5-phospho-alpha-D-ribose 1-diphosphate; anthranilate phosphoribosyltransferase 1690968 trpD 7681270 trpD Streptococcus pneumoniae P1031 anthranilate phosphoribosyltransferase YP_002738924.1 1689964 R 488223 CDS YP_002738925.1 225857414 7681931 complement(1690979..1691545) 1 NC_012467.1 TrpG; with TrpE catalyzes the formation of anthranilate and glutamate from chorismate and glutamine; TrpG provides the glutamine amidotransferase activity; anthranilate synthase component II 1691545 7681931 SPP_1824 Streptococcus pneumoniae P1031 anthranilate synthase component II YP_002738925.1 1690979 R 488223 CDS YP_002738926.1 225857415 7682423 complement(1691542..1692903) 1 NC_012467.1 with component II, the glutamine amidotransferase, catalyzes the formation of anthranilate from chorismate and glutamine; anthranilate synthase component I 1692903 trpE 7682423 trpE Streptococcus pneumoniae P1031 anthranilate synthase component I YP_002738926.1 1691542 R 488223 CDS YP_002738927.1 225857416 7681524 complement(1693275..1693436) 1 NC_012467.1 hypothetical protein 1693436 7681524 SPP_1826 Streptococcus pneumoniae P1031 hypothetical protein YP_002738927.1 1693275 R 488223 CDS YP_002738928.1 225857417 7681376 complement(1694044..1695045) 1 NC_012467.1 identified by match to protein family HMM PF00356; match to protein family HMM PF00532; catabolite control protein 1695045 7681376 SPP_1827 Streptococcus pneumoniae P1031 catabolite control protein YP_002738928.1 1694044 R 488223 CDS YP_002738929.1 225857418 7682706 complement(1695617..1696327) 1 NC_012467.1 identified by match to protein family HMM PF02308; putative Mg2+ transporter-C (MgtC) family protein 1696327 7682706 SPP_1828 Streptococcus pneumoniae P1031 putative Mg2+ transporter-C (MgtC) family protein YP_002738929.1 1695617 R 488223 CDS YP_002738930.1 225857419 7682089 complement(1696330..1698021) 1 NC_012467.1 identified by match to protein family HMM PF00528; binding-protein-dependent transport systems inner membrane component 1698021 7682089 SPP_1829 Streptococcus pneumoniae P1031 binding-protein-dependent transport systems inner membrane component YP_002738930.1 1696330 R 488223 CDS YP_002738931.1 225857420 7681705 complement(1698033..1699043) 1 NC_012467.1 identified by match to protein family HMM PF00005; match to protein family HMM PF03459; match to protein family HMM PF08402; spermidine/putrescine import ATP-binding protein PotA 1699043 7681705 SPP_1830 Streptococcus pneumoniae P1031 spermidine/putrescine import ATP-binding protein PotA YP_002738931.1 1698033 R 488223 CDS YP_002738932.1 225857421 7681794 complement(1699146..1700213) 1 NC_012467.1 ABC transporter substrate-binding protein 1700213 7681794 SPP_1831 Streptococcus pneumoniae P1031 ABC transporter substrate-binding protein YP_002738932.1 1699146 R 488223 CDS YP_002738933.1 225857422 7681975 complement(1700238..1700897) 1 NC_012467.1 identified by match to protein family HMM PF08975; hypothetical protein 1700897 7681975 SPP_1832 Streptococcus pneumoniae P1031 hypothetical protein YP_002738933.1 1700238 R 488223 CDS YP_002738934.1 225857423 7682601 complement(1701022..1701135) 1 NC_012467.1 hypothetical protein 1701135 7682601 SPP_1833 Streptococcus pneumoniae P1031 hypothetical protein YP_002738934.1 1701022 R 488223 CDS YP_002738935.1 225857424 7682586 complement(1701916..1704042) 1 NC_012467.1 identified by match to protein family HMM PF04650; match to protein family HMM TIGR01168; cell wall surface anchor family protein 1704042 7682586 SPP_1834 Streptococcus pneumoniae P1031 cell wall surface anchor family protein YP_002738935.1 1701916 R 488223 CDS YP_002738936.1 225857425 7681748 complement(1705205..1706431) 1 NC_012467.1 identified by match to protein family HMM PF01041; Cps7G 1706431 7681748 SPP_1835 Streptococcus pneumoniae P1031 Cps7G YP_002738936.1 1705205 R 488223 CDS YP_002738937.1 225857426 7682343 complement(1706474..1707166) 1 NC_012467.1 identified by match to protein family HMM PF02397; putative glycosyl transferase 1707166 7682343 SPP_1836 Streptococcus pneumoniae P1031 putative glycosyl transferase YP_002738937.1 1706474 R 488223 CDS YP_002738938.1 225857427 7681484 complement(1707352..1709103) 1 NC_012467.1 identified by match to protein family HMM PF00005; match to protein family HMM PF00664; ABC transporter ATP-binding protein 1709103 7681484 SPP_1837 Streptococcus pneumoniae P1031 ABC transporter ATP-binding protein YP_002738938.1 1707352 R 488223 CDS YP_002738939.1 225857428 7681443 complement(1709093..1710838) 1 NC_012467.1 identified by match to protein family HMM PF00005; match to protein family HMM PF00664; ABC transporter ATP-binding protein 1710838 7681443 SPP_1838 Streptococcus pneumoniae P1031 ABC transporter ATP-binding protein YP_002738939.1 1709093 R 488223 CDS YP_002738940.1 225857429 7681143 1710884..1710997 1 NC_012467.1 identified by glimmer; putative; hypothetical protein 1710997 7681143 SPP_1839 Streptococcus pneumoniae P1031 hypothetical protein YP_002738940.1 1710884 D 488223 CDS YP_002738941.1 225857430 7682215 complement(1711044..1711340) 1 NC_012467.1 identified by glimmer; putative; hypothetical protein 1711340 7682215 SPP_1840 Streptococcus pneumoniae P1031 hypothetical protein YP_002738941.1 1711044 R 488223 CDS YP_002738942.1 225857431 7681403 complement(1711493..1711768) 1 NC_012467.1 identified by glimmer; putative; hypothetical protein 1711768 7681403 SPP_1841 Streptococcus pneumoniae P1031 hypothetical protein YP_002738942.1 1711493 R 488223 CDS YP_002738943.1 225857432 7682335 complement(1711722..1711949) 1 NC_012467.1 identified by glimmer; putative; hypothetical protein 1711949 7682335 SPP_1842 Streptococcus pneumoniae P1031 hypothetical protein YP_002738943.1 1711722 R 488223 CDS YP_002738944.1 225857433 7681346 1712082..1712909 1 NC_012467.1 identified by match to protein family HMM PF03372; match to protein family HMM TIGR00195; match to protein family HMM TIGR00633; exodeoxyribonuclease III 1712909 xth 7681346 xth Streptococcus pneumoniae P1031 exodeoxyribonuclease III YP_002738944.1 1712082 D 488223 CDS YP_002738945.1 225857434 7681598 1714181..1714762 1 NC_012467.1 Catalyzes the transfer of the phosphoribosyl moiety from 5-phospho--D-ribosyl-1-pyrophosphate (PRib-PP) to the 6-oxo-guanine and -xanthine; xanthine phosphoribosyltransferase 1714762 xpt 7681598 xpt Streptococcus pneumoniae P1031 xanthine phosphoribosyltransferase YP_002738945.1 1714181 D 488223 CDS YP_002738946.1 225857435 7682168 1714762..1716024 1 NC_012467.1 identified by match to protein family HMM PF00860; match to protein family HMM PF00916; match to protein family HMM TIGR00801; match to protein family HMM TIGR03173; xanthine permease 1716024 7682168 SPP_1847 Streptococcus pneumoniae P1031 xanthine permease YP_002738946.1 1714762 D 488223 CDS YP_002738947.1 225857436 7681503 complement(1716111..1716977) 1 NC_012467.1 identified by match to protein family HMM PF04556; type II restriction enzyme 1716977 7681503 SPP_1848 Streptococcus pneumoniae P1031 type II restriction enzyme YP_002738947.1 1716111 R 488223 CDS YP_002738948.1 225857437 7682687 complement(1716964..1717734) 1 NC_012467.1 identified by match to protein family HMM PF01555; DNA methylase 1717734 7682687 SPP_1849 Streptococcus pneumoniae P1031 DNA methylase YP_002738948.1 1716964 R 488223 CDS YP_002738949.1 225857438 7682059 complement(1717760..1718614) 1 NC_012467.1 identified by match to protein family HMM PF02086; match to protein family HMM TIGR00571; modification methylase 1718614 7682059 SPP_1850 Streptococcus pneumoniae P1031 modification methylase YP_002738949.1 1717760 R 488223 CDS YP_002738950.1 225857439 7680930 complement(1718771..1719175) 1 NC_012467.1 identified by match to protein family HMM PF03061; match to protein family HMM TIGR00369; thioesterase family protein 1719175 7680930 SPP_1851 Streptococcus pneumoniae P1031 thioesterase family protein YP_002738950.1 1718771 R 488223 CDS YP_002738951.1 225857440 7681641 complement(1719245..1720726) 1 NC_012467.1 catalyzes the formation of alpha-D-glucose 1-phosphate and UDP-galactose from UDP-glucose and alpha-D-galactose 1-phosphate in galactose metabolism; galactose-1-phosphate uridylyltransferase 1720726 galT 7681641 galT Streptococcus pneumoniae P1031 galactose-1-phosphate uridylyltransferase YP_002738951.1 1719245 R 488223 CDS YP_002738952.1 225857441 7681858 complement(1720745..1721923) 1 NC_012467.1 catalyzes the formation of alpha-D-galactose 1-phosphate from D-galactose in galactose metabolism; galactokinase 1721923 galK 7681858 galK Streptococcus pneumoniae P1031 galactokinase YP_002738952.1 1720745 R 488223 CDS YP_002738953.1 225857442 7682131 1722087..1723094 1 NC_012467.1 identified by match to protein family HMM PF00356; match to protein family HMM PF00532; GalR, member of GalR-LacI family of transcriptional regulators, binds DNA; regulator of gal operon 1723094 7682131 SPP_1854 Streptococcus pneumoniae P1031 GalR, member of GalR-LacI family of transcriptional regulators, binds DNA; regulator of gal operon YP_002738953.1 1722087 D 488223 CDS YP_002738954.1 225857443 7681556 complement(1723140..1724177) 1 NC_012467.1 identified by match to protein family HMM PF00107; match to protein family HMM PF08240; alcohol dehydrogenase, zinc-containing 1724177 7681556 SPP_1855 Streptococcus pneumoniae P1031 alcohol dehydrogenase, zinc-containing YP_002738954.1 1723140 R 488223 CDS YP_002738955.1 225857444 7682257 complement(1724178..1724531) 1 NC_012467.1 identified by match to protein family HMM PF00376; transcriptional regulator, MerR family 1724531 7682257 SPP_1856 Streptococcus pneumoniae P1031 transcriptional regulator, MerR family YP_002738955.1 1724178 R 488223 CDS YP_002738956.1 225857445 7681934 complement(1724775..1725665) 1 NC_012467.1 identified by match to protein family HMM PF01545; match to protein family HMM TIGR01297; cation diffusion facilitator transporter - heavy metal transport 1725665 7681934 SPP_1857 Streptococcus pneumoniae P1031 cation diffusion facilitator transporter - heavy metal transport YP_002738956.1 1724775 R 488223 CDS YP_002738957.1 225857446 7681462 1725798..1726334 1 NC_012467.1 identified by match to protein family HMM PF00440; TetR family transcriptional regulator 1726334 7681462 SPP_1858 Streptococcus pneumoniae P1031 TetR family transcriptional regulator YP_002738957.1 1725798 D 488223 CDS YP_002738958.1 225857447 7682234 complement(1726500..1727306) 1 NC_012467.1 identified by match to protein family HMM PF04973; match to protein family HMM TIGR01528; nicotinamide mononucleotide transporter 1727306 7682234 SPP_1859 Streptococcus pneumoniae P1031 nicotinamide mononucleotide transporter YP_002738958.1 1726500 R 488223 CDS YP_002738959.1 225857448 7681348 complement(1727830..1729176) 1 NC_012467.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop; identified by match to protein family HMM PF01609; Spn1 transposase 1729176 7681348 SPP_1860 Streptococcus pneumoniae P1031 Spn1 transposase YP_002738959.1 1727830 R 488223 CDS YP_002738960.1 225857449 7681351 complement(1729359..1730879) 1 NC_012467.1 identified by match to protein family HMM PF00528; match to protein family HMM PF04069; choline ABC transporter permease 1730879 7681351 SPP_1861 Streptococcus pneumoniae P1031 choline ABC transporter permease YP_002738960.1 1729359 R 488223 CDS YP_002738961.1 225857450 7681819 complement(1730872..1731600) 1 NC_012467.1 identified by match to protein family HMM PF00005; choline transport ATP-binding protein opuBA 1731600 7681819 SPP_1862 Streptococcus pneumoniae P1031 choline transport ATP-binding protein opuBA YP_002738961.1 1730872 R 488223 CDS YP_002738962.1 225857451 7681317 complement(1731615..1732379) 1 NC_012467.1 identified by match to protein family HMM PF07366; hypothetical protein 1732379 7681317 SPP_1863 Streptococcus pneumoniae P1031 hypothetical protein YP_002738962.1 1731615 R 488223 CDS YP_002738963.1 225857452 7682697 complement(1732383..1732826) 1 NC_012467.1 identified by match to protein family HMM PF01047; transcriptional regulator, MarR family 1732826 7682697 SPP_1864 Streptococcus pneumoniae P1031 transcriptional regulator, MarR family YP_002738963.1 1732383 R 488223 CDS YP_002738964.1 225857453 7680970 complement(1733508..1733804) 1 NC_012467.1 identified by match to protein family HMM PF08957; hypothetical protein 1733804 7680970 SPP_1865 Streptococcus pneumoniae P1031 hypothetical protein YP_002738964.1 1733508 R 488223 CDS YP_002738965.1 225857454 7681050 complement(1733826..1734890) 1 NC_012467.1 identified by match to protein family HMM PF05343; match to protein family HMM TIGR03107; glutamyl aminopeptidase 1734890 pepA 7681050 pepA Streptococcus pneumoniae P1031 glutamyl aminopeptidase YP_002738965.1 1733826 R 488223 CDS YP_002738966.1 225857455 7681836 complement(1735046..1735204) 1 NC_012467.1 identified by glimmer; putative; hypothetical protein 1735204 7681836 SPP_1867 Streptococcus pneumoniae P1031 hypothetical protein YP_002738966.1 1735046 R 488223 CDS YP_002738967.1 225857456 7681703 1736416..1737375 1 NC_012467.1 identified by match to protein family HMM PF01032; Fe3+ ABC transporter permease 1737375 7681703 SPP_1869 Streptococcus pneumoniae P1031 Fe3+ ABC transporter permease YP_002738967.1 1736416 D 488223 CDS YP_002738968.1 225857457 7682556 1737365..1738321 1 NC_012467.1 identified by match to protein family HMM PF01032; Fe3+ ABC transporter permease 1738321 7682556 SPP_1870 Streptococcus pneumoniae P1031 Fe3+ ABC transporter permease YP_002738968.1 1737365 D 488223 CDS YP_002738969.1 225857458 7681205 1738318..1739070 1 NC_012467.1 identified by match to protein family HMM PF00005; ferrichrome transport ATP-binding protein FhuC 1739070 7681205 SPP_1871 Streptococcus pneumoniae P1031 ferrichrome transport ATP-binding protein FhuC YP_002738969.1 1738318 D 488223 CDS YP_002738970.1 225857459 7681842 1739166..1740131 1 NC_012467.1 identified by match to protein family HMM PF01497; iron-compound ABC transporter, iron-compound-binding protein 1740131 7681842 SPP_1872 Streptococcus pneumoniae P1031 iron-compound ABC transporter, iron-compound-binding protein YP_002738970.1 1739166 D 488223 CDS YP_002738971.1 225857460 7682725 complement(1740356..1740598) 1 NC_012467.1 identified by match to protein family HMM PF01809; match to protein family HMM TIGR00278; hypothetical protein 1740598 7682725 SPP_1873 Streptococcus pneumoniae P1031 hypothetical protein YP_002738971.1 1740356 R 488223 CDS YP_002738972.1 225857461 7681363 complement(1740598..1741320) 1 NC_012467.1 identified by match to protein family HMM PF00849; match to protein family HMM PF01479; match to protein family HMM TIGR00093; ribosomal large subunit pseudouridine synthase B 1741320 rluB 7681363 rluB Streptococcus pneumoniae P1031 ribosomal large subunit pseudouridine synthase B YP_002738972.1 1740598 R 488223 CDS YP_002738973.1 225857462 7681497 complement(1741307..1741876) 1 NC_012467.1 functions during chromosome segregation; may form a condensin-like structure with SMC and ScpA; forms a homodimer; segregation and condensation protein B 1741876 scpB 7681497 scpB Streptococcus pneumoniae P1031 segregation and condensation protein B YP_002738973.1 1741307 R 488223 CDS YP_002738974.1 225857463 7682425 complement(1741895..1742623) 1 NC_012467.1 functions during chromosome segregation; may form a condensin-like structure with SMC and ScpB; segregation and condensation protein A 1742623 scpA 7682425 scpA Streptococcus pneumoniae P1031 segregation and condensation protein A YP_002738974.1 1741895 R 488223 CDS YP_002738975.1 225857464 7681715 complement(1742623..1743363) 1 NC_012467.1 site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs; site-specific tyrosine recombinase XerD-like protein 1743363 xerD 7681715 xerD Streptococcus pneumoniae P1031 site-specific tyrosine recombinase XerD-like protein YP_002738975.1 1742623 R 488223 CDS YP_002738976.1 225857465 7682594 complement(1743354..1743815) 1 NC_012467.1 identified by match to protein family HMM PF00571; CBS domain protein 1743815 7682594 SPP_1878 Streptococcus pneumoniae P1031 CBS domain protein YP_002738976.1 1743354 R 488223 CDS YP_002738977.1 225857466 7681115 complement(1743812..1744333) 1 NC_012467.1 identified by match to protein family HMM PF00149; match to protein family HMM TIGR00040; phosphodiesterase, family 1744333 7681115 SPP_1879 Streptococcus pneumoniae P1031 phosphodiesterase, family YP_002738977.1 1743812 R 488223 CDS YP_002738978.1 225857467 7680624 complement(1744309..1745280) 1 NC_012467.1 HAM1-like protein; Rec-dependent growth; RgdB; yggV; it is suspected that this protein functions to remove misincorporated bases such as xanthine or hypoxanthine; deoxyribonucleotide triphosphate pyrophosphatase/hypothetical protein 1745280 7680624 SPP_1880 Streptococcus pneumoniae P1031 deoxyribonucleotide triphosphate pyrophosphatase/hypothetical protein YP_002738978.1 1744309 R 488223 CDS YP_002738979.1 225857468 7680628 complement(1745277..1746071) 1 NC_012467.1 converts L-glutamate to D-glutamate, a component of peptidoglycan; glutamate racemase 1746071 murI 7680628 murI Streptococcus pneumoniae P1031 glutamate racemase YP_002738979.1 1745277 R 488223 CDS YP_002738980.1 225857469 7682761 complement(1746278..1746526) 1 NC_012467.1 identified by match to protein family HMM PF03672; hypothetical protein 1746526 7682761 SPP_1882 Streptococcus pneumoniae P1031 hypothetical protein YP_002738980.1 1746278 R 488223 CDS YP_002738981.1 225857470 7681871 complement(1746668..1748293) 1 NC_012467.1 identified by match to protein family HMM PF00128; match to protein family HMM TIGR02403; alpha,alpha-phosphotrehalase 1748293 treC 7681871 treC Streptococcus pneumoniae P1031 alpha,alpha-phosphotrehalase YP_002738981.1 1746668 R 488223 CDS YP_002738982.1 225857471 7682084 complement(1748471..1750438) 1 NC_012467.1 identified by match to protein family HMM PF00358; match to protein family HMM PF00367; match to protein family HMM PF02378; match to protein family HMM TIGR00826; match to protein family HMM TIGR00830; match to protein family HMM TIGR01992; pts system, trehalose-specific iibc component 1750438 treP 7682084 treP Streptococcus pneumoniae P1031 pts system, trehalose-specific iibc component YP_002738982.1 1748471 R 488223 CDS YP_002738983.1 225857472 7681283 1750623..1751333 1 NC_012467.1 identified by match to protein family HMM PF00392; match to protein family HMM PF07702; match to protein family HMM TIGR02404; trehalose operon repressor 1751333 treR 7681283 treR Streptococcus pneumoniae P1031 trehalose operon repressor YP_002738983.1 1750623 D 488223 CDS YP_002738984.1 225857473 7681947 complement(1751366..1752169) 1 NC_012467.1 identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 1752169 7681947 SPP_1886 Streptococcus pneumoniae P1031 ABC transporter ATP-binding protein YP_002738984.1 1751366 R 488223 CDS YP_002738985.1 225857474 7682605 1753974..1754102 1 NC_012467.1 identified by glimmer; putative; hypothetical protein 1754102 7682605 SPP_1891 Streptococcus pneumoniae P1031 hypothetical protein YP_002738985.1 1753974 D 488223 CDS YP_002738986.1 225857475 7680841 complement(1754500..1755426) 1 NC_012467.1 identified by match to protein family HMM PF00005; match to protein family HMM PF08352; oligopeptide transport ATP-binding protein AmiF 1755426 7680841 SPP_1892 Streptococcus pneumoniae P1031 oligopeptide transport ATP-binding protein AmiF YP_002738986.1 1754500 R 488223 CDS YP_002738987.1 225857476 7682671 complement(1755437..1756504) 1 NC_012467.1 identified by match to protein family HMM PF00005; match to protein family HMM PF08352; match to protein family HMM TIGR01727; oligopeptide transport ATP-binding protein OppD 1756504 7682671 SPP_1893 Streptococcus pneumoniae P1031 oligopeptide transport ATP-binding protein OppD YP_002738987.1 1755437 R 488223 CDS YP_002738988.1 225857477 7682688 complement(1756513..1757439) 1 NC_012467.1 identified by match to protein family HMM PF00528; oligopeptide transport system permease protein AmiD 1757439 7682688 SPP_1894 Streptococcus pneumoniae P1031 oligopeptide transport system permease protein AmiD YP_002738988.1 1756513 R 488223 CDS YP_002738989.1 225857478 7680987 complement(1757439..1758935) 1 NC_012467.1 identified by match to protein family HMM PF00528; oligopeptide transport system permease protein AmiC 1758935 7680987 SPP_1895 Streptococcus pneumoniae P1031 oligopeptide transport system permease protein AmiC YP_002738989.1 1757439 R 488223 CDS YP_002738990.1 225857479 7682163 complement(1759002..1760981) 1 NC_012467.1 identified by match to protein family HMM PF00496; AmiA protein 1760981 7682163 SPP_1896 Streptococcus pneumoniae P1031 AmiA protein YP_002738990.1 1759002 R 488223 CDS YP_002738991.1 225857480 7681086 1761109..1761276 1 NC_012467.1 hypothetical protein 1761276 7681086 SPP_1897 Streptococcus pneumoniae P1031 hypothetical protein YP_002738991.1 1761109 D 488223 CDS YP_002738992.1 225857481 7681806 complement(1761668..1762861) 1 NC_012467.1 identified by match to protein family HMM PF04932; O-antigen polymerase family 1762861 7681806 SPP_1898 Streptococcus pneumoniae P1031 O-antigen polymerase family YP_002738992.1 1761668 R 488223 CDS YP_002738993.1 225857482 7681065 complement(1762999..1764441) 1 NC_012467.1 identified by match to protein family HMM PF00128; sucrose phosphorylase (Sucrose glucosyltransferase)(Glucosyltransferase-A) (GTF-A) 1764441 7681065 SPP_1899 Streptococcus pneumoniae P1031 sucrose phosphorylase (Sucrose glucosyltransferase)(Glucosyltransferase-A) (GTF-A) YP_002738993.1 1762999 R 488223 CDS YP_002738994.1 225857483 7682669 complement(1764625..1764792) 1 NC_012467.1 hypothetical protein 1764792 7682669 SPP_1900 Streptococcus pneumoniae P1031 hypothetical protein YP_002738994.1 1764625 R 488223 CDS YP_002738995.1 225857484 7681643 complement(1764799..1765632) 1 NC_012467.1 identified by match to protein family HMM PF00528; sugar ABC transporter permease 1765632 7681643 SPP_1901 Streptococcus pneumoniae P1031 sugar ABC transporter permease YP_002738995.1 1764799 R 488223 CDS YP_002738996.1 225857485 7680974 complement(1765646..1766512) 1 NC_012467.1 identified by match to protein family HMM PF00528; sugar ABC transporter permease 1766512 7680974 SPP_1902 Streptococcus pneumoniae P1031 sugar ABC transporter permease YP_002738996.1 1765646 R 488223 CDS YP_002738997.1 225857486 7681093 complement(1766526..1767785) 1 NC_012467.1 identified by match to protein family HMM PF01547; sugar ABC transporter substrate-binding protein 1767785 7681093 SPP_1903 Streptococcus pneumoniae P1031 sugar ABC transporter substrate-binding protein YP_002738997.1 1766526 R 488223 CDS YP_002738998.1 225857487 7680795 complement(1767877..1770039) 1 NC_012467.1 identified by match to protein family HMM PF02065; alpha-galactosidase AgaN 1770039 7680795 SPP_1904 Streptococcus pneumoniae P1031 alpha-galactosidase AgaN YP_002738998.1 1767877 R 488223 CDS YP_002738999.1 225857488 7682483 1770147..1771007 1 NC_012467.1 identified by match to protein family HMM PF00165; match to protein family HMM PF02311; Msm operon regulatory protein 1771007 7682483 SPP_1905 Streptococcus pneumoniae P1031 Msm operon regulatory protein YP_002738999.1 1770147 D 488223 CDS YP_002739000.1 225857489 7681695 1771004..1771939 1 NC_012467.1 catalyzes the formation of biotinyl-5'-AMP, also acts as a transcriptional repressor of the biotin operon; biotin--protein ligase 1771939 7681695 SPP_1906 Streptococcus pneumoniae P1031 biotin--protein ligase YP_002739000.1 1771004 D 488223 CDS YP_002739001.1 225857490 7680736 complement(1778843..1780198) 1 NC_012467.1 identified by match to protein family HMM PF01938; match to protein family HMM PF05958; match to protein family HMM TIGR00479; 23S rRNA (uracil-5-)-methyltransferase RumA 1780198 rumA2 7680736 rumA2 Streptococcus pneumoniae P1031 23S rRNA (uracil-5-)-methyltransferase RumA YP_002739001.1 1778843 R 488223 CDS YP_002739002.1 225857491 7681652 1780168..1781031 1 NC_012467.1 identified by match to protein family HMM PF01636; aminoglycoside phosphotransferase 1781031 7681652 SPP_1930 Streptococcus pneumoniae P1031 aminoglycoside phosphotransferase YP_002739002.1 1780168 D 488223 CDS YP_002739003.1 225857492 7682394 1781041..1781817 1 NC_012467.1 binds RecA and inhibits RecA-mediated DNA strand exchange and ATP hydrolysis and coprotease activities; recombination regulator RecX 1781817 recX 7682394 recX Streptococcus pneumoniae P1031 recombination regulator RecX YP_002739003.1 1781041 D 488223 CDS YP_002739004.1 225857493 7682357 1781906..1782439 1 NC_012467.1 identified by match to protein family HMM PF04167; hypothetical protein 1782439 7682357 SPP_1932 Streptococcus pneumoniae P1031 hypothetical protein YP_002739004.1 1781906 D 488223 CDS YP_002739005.1 225857494 7680697 complement(1783773..1785395) 1 NC_012467.1 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth; chaperonin GroEL 1785395 groEL 7680697 groEL Streptococcus pneumoniae P1031 chaperonin GroEL YP_002739005.1 1783773 R 488223 CDS YP_002739006.1 225857495 7682767 complement(1785411..1785695) 1 NC_012467.1 10 kDa chaperonin; Cpn10; GroES; forms homoheptameric ring; binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it; folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES; release of the folded substrate is dependent on ATP binding and hydrolysis in the trans ring; co-chaperonin GroES 1785695 groES 7682767 groES Streptococcus pneumoniae P1031 co-chaperonin GroES YP_002739006.1 1785411 R 488223 CDS YP_002739007.1 225857496 7681458 complement(1785965..1786360) 1 NC_012467.1 binds to single stranded DNA and may facilitate the binding and interaction of other proteins to DNA; single-stranded DNA-binding protein 1786360 7681458 SPP_1937 Streptococcus pneumoniae P1031 single-stranded DNA-binding protein YP_002739007.1 1785965 R 488223 CDS YP_002739008.1 225857497 7681534 complement(1786438..1787199) 1 NC_012467.1 identified by match to protein family HMM PF00106; match to protein family HMM PF08659; oxidoreductase, short chain dehydrogenase/reductase family 1787199 7681534 SPP_1938 Streptococcus pneumoniae P1031 oxidoreductase, short chain dehydrogenase/reductase family YP_002739008.1 1786438 R 488223 CDS YP_002739009.1 225857498 7680954 complement(1787232..1787858) 1 NC_012467.1 identified by match to protein family HMM PF01588; putative tRNA binding domain protein 1787858 7680954 SPP_1939 Streptococcus pneumoniae P1031 putative tRNA binding domain protein YP_002739009.1 1787232 R 488223 CDS YP_002739010.1 225857499 7682003 complement(1787874..1788191) 1 NC_012467.1 identified by match to protein family HMM PF00085; thioredoxin family protein 1788191 7682003 SPP_1940 Streptococcus pneumoniae P1031 thioredoxin family protein YP_002739010.1 1787874 R 488223 CDS YP_002739011.1 225857500 7680806 complement(1788188..1788487) 1 NC_012467.1 hypothetical protein 1788487 7680806 SPP_1941 Streptococcus pneumoniae P1031 hypothetical protein YP_002739011.1 1788188 R 488223 CDS YP_002739012.1 225857501 7682841 complement(1788772..1788963) 1 NC_012467.1 identified by match to protein family HMM PF01473; hypothetical protein 1788963 7682841 SPP_1942 Streptococcus pneumoniae P1031 hypothetical protein YP_002739012.1 1788772 R 488223 CDS YP_002739013.1 225857502 7681916 complement(1789124..1789798) 1 NC_012467.1 hypothetical protein 1789798 7681916 SPP_1943 Streptococcus pneumoniae P1031 hypothetical protein YP_002739013.1 1789124 R 488223 CDS YP_002739014.1 225857503 7682808 complement(1789803..1790249) 1 NC_012467.1 identified by match to protein family HMM PF04397; response regulator of the LytR/AlgR family 1790249 7682808 SPP_1944 Streptococcus pneumoniae P1031 response regulator of the LytR/AlgR family YP_002739014.1 1789803 R 488223 CDS YP_002739015.1 225857504 7682604 complement(1790363..1790866) 1 NC_012467.1 identified by match to protein family HMM PF01569; PAP2 family protein 1790866 7682604 SPP_1945 Streptococcus pneumoniae P1031 PAP2 family protein YP_002739015.1 1790363 R 488223 CDS YP_002739016.1 225857505 7681144 complement(1790863..1791225) 1 NC_012467.1 hypothetical protein 1791225 7681144 SPP_1946 Streptococcus pneumoniae P1031 hypothetical protein YP_002739016.1 1790863 R 488223 CDS YP_002739017.1 225857506 7681663 complement(1793760..1794476) 1 NC_012467.1 identified by match to protein family HMM PF01709; match to protein family HMM TIGR01033; hypothetical protein 1794476 7681663 SPP_1952 Streptococcus pneumoniae P1031 hypothetical protein YP_002739017.1 1793760 R 488223 CDS YP_002739018.1 225857507 7682863 complement(1795357..1796772) 1 NC_012467.1 identified by match to protein family HMM PF01289; pneumolysin (Thiol-activated cytolysin) 1796772 7682863 SPP_1953 Streptococcus pneumoniae P1031 pneumolysin (Thiol-activated cytolysin) YP_002739018.1 1795357 R 488223 CDS YP_002739019.1 225857508 7682004 complement(1796783..1797193) 1 NC_012467.1 hypothetical protein 1797193 7682004 SPP_1954 Streptococcus pneumoniae P1031 hypothetical protein YP_002739019.1 1796783 R 488223 CDS YP_002739020.1 225857509 7681041 complement(1797186..1797794) 1 NC_012467.1 hypothetical protein 1797794 7681041 SPP_1955 Streptococcus pneumoniae P1031 hypothetical protein YP_002739020.1 1797186 R 488223 CDS YP_002739021.1 225857510 7681042 complement(1797807..1798265) 1 NC_012467.1 hypothetical protein 1798265 7681042 SPP_1956 Streptococcus pneumoniae P1031 hypothetical protein YP_002739021.1 1797807 R 488223 CDS YP_002739022.1 225857511 7680906 1798390..1798521 1 NC_012467.1 mobile genetic element 1798521 7680906 SPP_1957 Streptococcus pneumoniae P1031 mobile genetic element YP_002739022.1 1798390 D 488223 CDS YP_002739023.1 225857512 7681891 1798526..1798789 1 NC_012467.1 mobile genetic element 1798789 7681891 SPP_1958 Streptococcus pneumoniae P1031 mobile genetic element YP_002739023.1 1798526 D 488223 CDS YP_002739024.1 225857513 7681136 complement(1799554..1799814) 1 NC_012467.1 hypothetical protein 1799814 7681136 SPP_1959 Streptococcus pneumoniae P1031 hypothetical protein YP_002739024.1 1799554 R 488223 CDS YP_002739025.1 225857514 7682274 complement(1799873..1800424) 1 NC_012467.1 hypothetical protein 1800424 7682274 SPP_1960 Streptococcus pneumoniae P1031 hypothetical protein YP_002739025.1 1799873 R 488223 CDS YP_002739026.1 225857515 7682408 complement(1800414..1800611) 1 NC_012467.1 hypothetical protein 1800611 7682408 SPP_1961 Streptococcus pneumoniae P1031 hypothetical protein YP_002739026.1 1800414 R 488223 CDS YP_002739027.1 225857516 7682112 complement(1800615..1801199) 1 NC_012467.1 hypothetical protein 1801199 7682112 SPP_1962 Streptococcus pneumoniae P1031 hypothetical protein YP_002739027.1 1800615 R 488223 CDS YP_002739028.1 225857517 7682222 complement(1801597..1802022) 1 NC_012467.1 hypothetical protein 1802022 7682222 SPP_1963 Streptococcus pneumoniae P1031 hypothetical protein YP_002739028.1 1801597 R 488223 CDS YP_002739029.1 225857518 7681603 complement(1802151..1802510) 1 NC_012467.1 hypothetical protein 1802510 7681603 SPP_1964 Streptococcus pneumoniae P1031 hypothetical protein YP_002739029.1 1802151 R 488223 CDS YP_002739030.1 225857519 7682700 complement(1802749..1802910) 1 NC_012467.1 type II restriction-modification system regulatory protein, putative 1802910 7682700 SPP_1965 Streptococcus pneumoniae P1031 type II restriction-modification system regulatory protein, putative YP_002739030.1 1802749 R 488223 CDS YP_002739031.1 225857520 7682105 complement(1803269..1804225) 1 NC_012467.1 identified by match to protein family HMM PF01473; match to protein family HMM PF01510; autolysin (N-acetylmuramoyl-L-alanine amidase) (Mureinhydrolase) (Mucopeptide aminohydrolase) (Cell wall hydrolase) 1804225 7682105 SPP_1966 Streptococcus pneumoniae P1031 autolysin (N-acetylmuramoyl-L-alanine amidase) (Mureinhydrolase) (Mucopeptide aminohydrolase) (Cell wall hydrolase) YP_002739031.1 1803269 R 488223 CDS YP_002739032.1 225857521 7681707 complement(1804601..1805971) 1 NC_012467.1 identified by match to protein family HMM PF01554; match to protein family HMM TIGR00797; DNA-damage-inducible protein 1805971 7681707 SPP_1967 Streptococcus pneumoniae P1031 DNA-damage-inducible protein YP_002739032.1 1804601 R 488223 CDS YP_002739033.1 225857522 7682326 complement(1806278..1807444) 1 NC_012467.1 catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs; recombinase A 1807444 recA 7682326 recA Streptococcus pneumoniae P1031 recombinase A YP_002739033.1 1806278 R 488223 CDS YP_002739034.1 225857523 7682678 complement(1807499..1808755) 1 NC_012467.1 identified by match to protein family HMM PF00994; match to protein family HMM PF02464; match to protein family HMM TIGR00199; match to protein family HMM TIGR00200; competence damage-inducible protein A 1808755 7682678 SPP_1969 Streptococcus pneumoniae P1031 competence damage-inducible protein A YP_002739034.1 1807499 R 488223 CDS YP_002739035.1 225857524 7681026 complement(1808840..1809856) 1 NC_012467.1 identified by match to protein family HMM PF03816; match to protein family HMM TIGR00350; regulator of lytrabc operon 1809856 7681026 SPP_1970 Streptococcus pneumoniae P1031 regulator of lytrabc operon YP_002739035.1 1808840 R 488223 CDS YP_002739036.1 225857525 7681345 complement(1809864..1810382) 1 NC_012467.1 identified by match to protein family HMM PF00583; acetyltransferase, gnat family 1810382 7681345 SPP_1971 Streptococcus pneumoniae P1031 acetyltransferase, gnat family YP_002739036.1 1809864 R 488223 CDS YP_002739037.1 225857526 7681226 complement(1810372..1810815) 1 NC_012467.1 identified by match to protein family HMM PF02367; match to protein family HMM TIGR00150; hypothetical protein 1810815 7681226 SPP_1972 Streptococcus pneumoniae P1031 hypothetical protein YP_002739037.1 1810372 R 488223 CDS YP_002739038.1 225857527 7680650 complement(1810901..1811521) 1 NC_012467.1 lipoprotein, putative 1811521 7680650 SPP_1973 Streptococcus pneumoniae P1031 lipoprotein, putative YP_002739038.1 1810901 R 488223 CDS YP_002739039.1 225857528 7682650 complement(1811904..1812767) 1 NC_012467.1 identified by match to protein family HMM PF01381; transcriptional activator 1812767 7682650 SPP_1974 Streptococcus pneumoniae P1031 transcriptional activator YP_002739039.1 1811904 R 488223 CDS YP_002739040.1 225857529 7681957 1812956..1813126 1 NC_012467.1 hypothetical protein 1813126 7681957 SPP_1975 Streptococcus pneumoniae P1031 hypothetical protein YP_002739040.1 1812956 D 488223 CDS YP_002739041.1 225857530 7682495 1813271..1815286 1 NC_012467.1 identified by match to protein family HMM PF07242; match to protein family HMM TIGR01654; bacteriocin-associated integral membrane protein 1815286 7682495 SPP_1976 Streptococcus pneumoniae P1031 bacteriocin-associated integral membrane protein YP_002739041.1 1813271 D 488223 CDS YP_002739042.1 225857531 7681547 1815288..1815920 1 NC_012467.1 identified by match to protein family HMM PF00005; antimicrobial peptide ABC transporter ATPase 1815920 7681547 SPP_1977 Streptococcus pneumoniae P1031 antimicrobial peptide ABC transporter ATPase YP_002739042.1 1815288 D 488223 CDS YP_002739043.1 225857532 7681878 1816061..1816339 1 NC_012467.1 hypothetical protein 1816339 7681878 SPP_1978 Streptococcus pneumoniae P1031 hypothetical protein YP_002739043.1 1816061 D 488223 CDS YP_002739044.1 225857533 7682769 complement(1816848..1817261) 1 NC_012467.1 catalyzes the formation of nucleoside triphosphate from ATP and nucleoside diphosphate; nucleoside diphosphate kinase 1817261 ndk 7682769 ndk Streptococcus pneumoniae P1031 nucleoside diphosphate kinase YP_002739044.1 1816848 R 488223 CDS YP_002739045.1 225857534 7682571 complement(1817372..1821049) 1 NC_012467.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Subunit beta' binds to sigma factor allowing it to bind to the -10 region of the promoter; DNA-directed RNA polymerase subunit beta' 1821049 rpoC 7682571 rpoC Streptococcus pneumoniae P1031 DNA-directed RNA polymerase subunit beta' YP_002739045.1 1817372 R 488223 CDS YP_002739046.1 225857535 7682759 complement(1821082..1824693) 1 NC_012467.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme; DNA-directed RNA polymerase subunit beta 1824693 rpoB 7682759 rpoB Streptococcus pneumoniae P1031 DNA-directed RNA polymerase subunit beta YP_002739046.1 1821082 R 488223 CDS YP_002739047.1 225857536 7680756 complement(1825377..1826708) 1 NC_012467.1 identified by match to protein family HMM PF00571; match to protein family HMM PF01595; match to protein family HMM PF03471; CBS domain protein 1826708 7680756 SPP_1983 Streptococcus pneumoniae P1031 CBS domain protein YP_002739047.1 1825377 R 488223 CDS YP_002739048.1 225857537 7681761 complement(1826999..1827823) 1 NC_012467.1 identified by match to protein family HMM PF01223; DNA-entry nuclease (Competence-specific nuclease) 1827823 7681761 SPP_1984 Streptococcus pneumoniae P1031 DNA-entry nuclease (Competence-specific nuclease) YP_002739048.1 1826999 R 488223 CDS YP_002739049.1 225857538 7682666 complement(1827862..1828050) 1 NC_012467.1 hypothetical protein 1828050 7682666 SPP_1985 Streptococcus pneumoniae P1031 hypothetical protein YP_002739049.1 1827862 R 488223 CDS YP_002739050.1 225857539 7681024 complement(1828043..1829326) 1 NC_012467.1 adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active; UDP-N-acetylglucosamine 1-carboxyvinyltransferase 1829326 murA2 7681024 murA2 Streptococcus pneumoniae P1031 UDP-N-acetylglucosamine 1-carboxyvinyltransferase YP_002739050.1 1828043 R 488223 CDS YP_002739051.1 225857540 7681665 complement(1829350..1829481) 1 NC_012467.1 hypothetical protein 1829481 7681665 SPP_1987 Streptococcus pneumoniae P1031 hypothetical protein YP_002739051.1 1829350 R 488223 CDS YP_002739052.1 225857541 7682330 complement(1829638..1830675) 1 NC_012467.1 ATP-dependent protease La 1830675 7682330 SPP_1988 Streptococcus pneumoniae P1031 ATP-dependent protease La YP_002739052.1 1829638 R 488223 CDS YP_002739053.1 225857542 7682294 complement(1830659..1831147) 1 NC_012467.1 Catalyzes the conversion of ATP and pantetheine 4'-phosphate to diphosphate and 3'-dephospho-coA; phosphopantetheine adenylyltransferase 1831147 coaD 7682294 coaD Streptococcus pneumoniae P1031 phosphopantetheine adenylyltransferase YP_002739053.1 1830659 R 488223 CDS YP_002739054.1 225857543 7680668 complement(1831137..1831676) 1 NC_012467.1 identified by match to protein family HMM PF03602; match to protein family HMM TIGR00095; RNA methyltransferase, RsmD family 1831676 rsmD 7680668 rsmD Streptococcus pneumoniae P1031 RNA methyltransferase, RsmD family YP_002739054.1 1831137 R 488223 CDS YP_002739055.1 225857544 7681172 complement(1831741..1832733) 1 NC_012467.1 catalyzes the formation of asparagine from aspartate and ammonia; asparagine synthetase AsnA 1832733 asnA 7681172 asnA Streptococcus pneumoniae P1031 asparagine synthetase AsnA YP_002739055.1 1831741 R 488223 CDS YP_002739056.1 225857545 7682503 1832707..1832838 1 NC_012467.1 identified by glimmer; putative; hypothetical protein 1832838 7682503 SPP_1992 Streptococcus pneumoniae P1031 hypothetical protein YP_002739056.1 1832707 D 488223 CDS YP_002739057.1 225857546 7680810 complement(1832844..1833527) 1 NC_012467.1 identified by match to protein family HMM PF01027; membrane protein 1833527 7680810 SPP_1993 Streptococcus pneumoniae P1031 membrane protein YP_002739057.1 1832844 R 488223 CDS YP_002739058.1 225857547 7682677 complement(1833583..1834323) 1 NC_012467.1 identified by match to protein family HMM PF00588; match to protein family HMM PF08032; rRNA/tRNA methylase 1834323 7682677 SPP_1994 Streptococcus pneumoniae P1031 rRNA/tRNA methylase YP_002739058.1 1833583 R 488223 CDS YP_002739059.1 225857548 7681981 1834357..1834635 1 NC_012467.1 catalyzes the hydrolysis of acylphosphate; acylphosphatase 1834635 7681981 SPP_1995 Streptococcus pneumoniae P1031 acylphosphatase YP_002739059.1 1834357 D 488223 CDS YP_002739060.1 225857549 7682497 1834713..1835639 1 NC_012467.1 involved in biogenesis of membrane proteins; Firmicutes specific proteins are shorter than other bacterial counterparts and have a signal peptide and lipid attachment site; OxaA-like protein precursor 1835639 7682497 SPP_1996 Streptococcus pneumoniae P1031 OxaA-like protein precursor YP_002739060.1 1834713 D 488223 CDS YP_002739061.1 225857550 7681853 complement(1835714..1836508) 1 NC_012467.1 identified by match to protein family HMM PF04055; match to protein family HMM TIGR02493; pyruvate formate-lyase 1-activating enzyme 1836508 pflA 7681853 pflA Streptococcus pneumoniae P1031 pyruvate formate-lyase 1-activating enzyme YP_002739061.1 1835714 R 488223 CDS YP_002739062.1 225857551 7682801 complement(1836634..1837884) 1 NC_012467.1 identified by match to protein family HMM PF00278; match to protein family HMM PF02784; diaminopimelate decarboxylase 1837884 7682801 SPP_1998 Streptococcus pneumoniae P1031 diaminopimelate decarboxylase YP_002739062.1 1836634 R 488223 CDS YP_002739063.1 225857552 7681724 complement(1837951..1838778) 1 NC_012467.1 identified by match to protein family HMM PF00156; match to protein family HMM PF09182; match to protein family HMM TIGR01743; pur operon repressor 1838778 purR 7681724 purR Streptococcus pneumoniae P1031 pur operon repressor YP_002739063.1 1837951 R 488223 CDS YP_002739064.1 225857553 7681239 complement(1839045..1839986) 1 NC_012467.1 identified by match to protein family HMM PF01336; match to protein family HMM PF01966; 3'-5' exoribonuclease YhaM 1839986 7681239 SPP_2000 Streptococcus pneumoniae P1031 3'-5' exoribonuclease YhaM YP_002739064.1 1839045 R 488223 CDS YP_002739065.1 225857554 7681866 complement(1839976..1841232) 1 NC_012467.1 identified by match to protein family HMM PF02646; competence-induced protein Ccs50 1841232 7681866 SPP_2001 Streptococcus pneumoniae P1031 competence-induced protein Ccs50 YP_002739065.1 1839976 R 488223 CDS YP_002739066.1 225857555 7681649 complement(1841234..1841896) 1 NC_012467.1 identified by match to protein family HMM PF04263; match to protein family HMM PF04265; match to protein family HMM TIGR01378; thiamine pyrophosphokinase 1841896 7681649 SPP_2002 Streptococcus pneumoniae P1031 thiamine pyrophosphokinase YP_002739066.1 1841234 R 488223 CDS YP_002739067.1 225857556 7681553 complement(1841859..1842515) 1 NC_012467.1 identified by match to protein family HMM PF00834; match to protein family HMM TIGR01163; ribulose-phosphate 3-epimerase 1842515 rpe 7681553 rpe Streptococcus pneumoniae P1031 ribulose-phosphate 3-epimerase YP_002739067.1 1841859 R 488223 CDS YP_002739068.1 225857557 7681213 complement(1842526..1843404) 1 NC_012467.1 EngC; RsgA; CpgA; circularly permuted GTPase; ribosome small subunit-dependent GTPase A; has the pattern G4-G1-G3 as opposed to other GTPases; interacts strongly with 30S ribosome which stimulates GTPase activity; ribosome-associated GTPase 1843404 rsgA 7681213 rsgA Streptococcus pneumoniae P1031 ribosome-associated GTPase YP_002739068.1 1842526 R 488223 CDS YP_002739069.1 225857558 7681726 complement(1843605..1844003) 1 NC_012467.1 identified by glimmer; putative; hypothetical protein 1844003 7681726 SPP_2005 Streptococcus pneumoniae P1031 hypothetical protein YP_002739069.1 1843605 R 488223 CDS YP_002739070.1 225857559 7682293 complement(1843997..1844770) 1 NC_012467.1 identified by glimmer; putative; hypothetical protein 1844770 7682293 SPP_2006 Streptococcus pneumoniae P1031 hypothetical protein YP_002739070.1 1843997 R 488223 CDS YP_002739071.1 225857560 7680689 complement(1845460..1846332) 1 NC_012467.1 catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin; dimethyladenosine transferase 1846332 ksgA 7680689 ksgA Streptococcus pneumoniae P1031 dimethyladenosine transferase YP_002739071.1 1845460 R 488223 CDS YP_002739072.1 225857561 7680836 complement(1846583..1846801) 1 NC_012467.1 identified by glimmer; putative; hypothetical protein 1846801 7680836 SPP_2008 Streptococcus pneumoniae P1031 hypothetical protein YP_002739072.1 1846583 R 488223 CDS YP_002739073.1 225857562 7681410 complement(1846869..1847510) 1 NC_012467.1 identified by match to protein family HMM PF00005; antimicrobial peptide ABC transporter ATPase 1847510 7681410 SPP_2009 Streptococcus pneumoniae P1031 antimicrobial peptide ABC transporter ATPase YP_002739073.1 1846869 R 488223 CDS YP_002739074.1 225857563 7681607 complement(1849810..1850709) 1 NC_012467.1 transcriptional activator 1850709 7681607 SPP_2012 Streptococcus pneumoniae P1031 transcriptional activator YP_002739074.1 1849810 R 488223 CDS YP_002739075.1 225857564 7681015 complement(1850781..1851341) 1 NC_012467.1 identified by match to protein family HMM PF01751; match to protein family HMM TIGR00334; putative primase homolog 1851341 7681015 SPP_2013 Streptococcus pneumoniae P1031 putative primase homolog YP_002739075.1 1850781 R 488223 CDS YP_002739076.1 225857565 7682010 complement(1851341..1852114) 1 NC_012467.1 identified by match to protein family HMM PF01026; match to protein family HMM TIGR00010; deoxyribonuclease TatD family 1852114 7682010 SPP_2014 Streptococcus pneumoniae P1031 deoxyribonuclease TatD family YP_002739076.1 1851341 R 488223 CDS YP_002739077.1 225857566 7680843 complement(1852419..1853312) 1 NC_012467.1 identified by match to protein family HMM PF00746; match to protein family HMM PF07564; match to protein family HMM TIGR01167; cell wall surface anchor family protein 1853312 7680843 SPP_2015 Streptococcus pneumoniae P1031 cell wall surface anchor family protein YP_002739077.1 1852419 R 488223 CDS YP_002739078.1 225857567 7680890 complement(1853596..1853730) 1 NC_012467.1 in Escherichia coli transcription of this gene is enhanced by polyamines; 50S ribosomal protein L34 1853730 rpmH 7680890 rpmH Streptococcus pneumoniae P1031 50S ribosomal protein L34 YP_002739078.1 1853596 R 488223 CDS YP_002739079.1 225857568 7682302 complement(1853875..1855089) 1 NC_012467.1 broad specificity; family IV; in Corynebacterium glutamicum this protein can use glutamate, 2-aminobutyrate, and aspartate as amino donors and pyruvate as the acceptor; aminotransferase AlaT 1855089 7682302 SPP_2017 Streptococcus pneumoniae P1031 aminotransferase AlaT YP_002739079.1 1853875 R 488223 CDS YP_002739080.1 225857569 7682579 complement(1855245..1855538) 1 NC_012467.1 hypothetical protein 1855538 7682579 SPP_2018 Streptococcus pneumoniae P1031 hypothetical protein YP_002739080.1 1855245 R 488223 CDS YP_002739081.1 225857570 7681207 1855700..1856152 1 NC_012467.1 identified by match to protein family HMM PF00582; universal stress protein family protein 1856152 7681207 SPP_2019 Streptococcus pneumoniae P1031 universal stress protein family protein YP_002739081.1 1855700 D 488223 CDS YP_002739082.1 225857571 7682185 complement(1856187..1857575) 1 NC_012467.1 identified by match to protein family HMM PF00702; match to protein family HMM PF05116; match to protein family HMM PF08282; match to protein family HMM TIGR00099; match to protein family HMM TIGR01484; Cof family protein 1857575 7682185 SPP_2020 Streptococcus pneumoniae P1031 Cof family protein YP_002739082.1 1856187 R 488223 CDS YP_002739083.1 225857572 7682282 1857641..1858603 1 NC_012467.1 identified by match to protein family HMM PF00710; L-asparaginase 1858603 7682282 SPP_2022 Streptococcus pneumoniae P1031 L-asparaginase YP_002739083.1 1857641 D 488223 CDS YP_002739084.1 225857573 7681090 complement(1858600..1858971) 1 NC_012467.1 hypothetical protein 1858971 7681090 SPP_2021 Streptococcus pneumoniae P1031 hypothetical protein YP_002739084.1 1858600 R 488223 CDS YP_002739085.1 225857574 7682073 complement(1859035..1860045) 1 NC_012467.1 identified by match to protein family HMM PF00356; match to protein family HMM PF00532; match to protein family HMM TIGR01481; catabolite control protein A 1860045 ccpA 7682073 ccpA Streptococcus pneumoniae P1031 catabolite control protein A YP_002739085.1 1859035 R 488223 CDS YP_002739086.1 225857575 7681028 complement(1860470..1861069) 1 NC_012467.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00196; response regulator 1861069 7681028 SPP_2024 Streptococcus pneumoniae P1031 response regulator YP_002739086.1 1860470 R 488223 CDS YP_002739087.1 225857576 7682251 complement(1861071..1862168) 1 NC_012467.1 identified by match to protein family HMM PF02518; match to protein family HMM PF07730; histidine kinase 1862168 7682251 SPP_2025 Streptococcus pneumoniae P1031 histidine kinase YP_002739087.1 1861071 R 488223 CDS YP_002739088.1 225857577 7681670 complement(1862168..1862905) 1 NC_012467.1 identified by match to protein family HMM PF01061; multidrug ABC transporter permease 1862905 7681670 SPP_2026 Streptococcus pneumoniae P1031 multidrug ABC transporter permease YP_002739088.1 1862168 R 488223 CDS YP_002739089.1 225857578 7680798 complement(1862907..1863791) 1 NC_012467.1 identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 1863791 7680798 SPP_2027 Streptococcus pneumoniae P1031 ABC transporter ATP-binding protein YP_002739089.1 1862907 R 488223 CDS YP_002739090.1 225857579 7682633 complement(1863778..1863972) 1 NC_012467.1 hypothetical protein 1863972 7682633 SPP_2028 Streptococcus pneumoniae P1031 hypothetical protein YP_002739090.1 1863778 R 488223 CDS YP_002739091.1 225857580 7680988 complement(1863969..1864175) 1 NC_012467.1 hypothetical protein 1864175 7680988 SPP_2029 Streptococcus pneumoniae P1031 hypothetical protein YP_002739091.1 1863969 R 488223 CDS YP_002739092.1 225857581 7680754 complement(1870856..1871335) 1 NC_012467.1 competence-specific global transcription modulator 1871335 7680754 SPP_2044 Streptococcus pneumoniae P1031 competence-specific global transcription modulator YP_002739092.1 1870856 R 488223 CDS YP_002739093.1 225857582 7682777 complement(1871457..1871993) 1 NC_012467.1 Modulates Rho-dependent transcription termination; transcription antitermination protein NusG 1871993 nusG 7682777 nusG Streptococcus pneumoniae P1031 transcription antitermination protein NusG YP_002739093.1 1871457 R 488223 CDS YP_002739094.1 225857583 7682435 complement(1872048..1872224) 1 NC_012467.1 forms a complex with SecY and SecG; SecYEG forms a putative protein-conducting channel to which secA binds and translocates targeted polypeptides across the cytoplasmic membrane, a process driven by ATP and a proton-motive force; preprotein translocase subunit SecE 1872224 secE 7682435 secE Streptococcus pneumoniae P1031 preprotein translocase subunit SecE YP_002739094.1 1872048 R 488223 CDS YP_002739095.1 225857584 7682350 complement(1872234..1872386) 1 NC_012467.1 in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group have the CXXC motif; 50S ribosomal protein L33 1872386 rpmG 7682350 rpmG Streptococcus pneumoniae P1031 50S ribosomal protein L33 YP_002739095.1 1872234 R 488223 CDS YP_002739096.1 225857585 7682028 complement(1872439..1874634) 1 NC_012467.1 identified by match to protein family HMM PF00905; match to protein family HMM PF00912; match to protein family HMM TIGR02074; penicillin-binding protein 2A 1874634 7682028 SPP_2048 Streptococcus pneumoniae P1031 penicillin-binding protein 2A YP_002739096.1 1872439 R 488223 CDS YP_002739097.1 225857586 7681664 1874760..1875596 1 NC_012467.1 identified by match to protein family HMM PF00849; ribosomal large subunit pseudouridine synthase, RluD subfamily 1875596 7681664 SPP_2049 Streptococcus pneumoniae P1031 ribosomal large subunit pseudouridine synthase, RluD subfamily YP_002739097.1 1874760 D 488223 CDS YP_002739098.1 225857587 7682114 complement(1875663..1876670) 1 NC_012467.1 identified by match to protein family HMM PF00044; match to protein family HMM PF02800; match to protein family HMM TIGR01534; glyceraldehyde-3-phosphate dehydrogenase, type I 1876670 gap 7682114 gap Streptococcus pneumoniae P1031 glyceraldehyde-3-phosphate dehydrogenase, type I YP_002739098.1 1875663 R 488223 CDS YP_002739099.1 225857588 7681080 complement(1876848..1877810) 1 NC_012467.1 identified by match to protein family HMM PF02687; efflux ABC transporter, permease protein 1877810 7681080 SPP_2051 Streptococcus pneumoniae P1031 efflux ABC transporter, permease protein YP_002739099.1 1876848 R 488223 CDS YP_002739100.1 225857589 7681618 complement(1877833..1877961) 1 NC_012467.1 identified by glimmer; putative; hypothetical protein 1877961 7681618 SPP_2052 Streptococcus pneumoniae P1031 hypothetical protein YP_002739100.1 1877833 R 488223 CDS YP_002739101.1 225857590 7682362 complement(1878368..1878718) 1 NC_012467.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by match to protein family HMM PF01710; transposase 1878718 7682362 SPP_2053 Streptococcus pneumoniae P1031 transposase YP_002739101.1 1878368 R 488223 CDS YP_002739102.1 225857591 7681386 complement(1878849..1879721) 1 NC_012467.1 catalyzes the formation of pyridine-2,3-dicarboxylate and 5-phospho-alpha-D-ribose 1-diphosphate from nictinate D-ribonucleotide; nicotinate-nucleotide pyrophosphorylase 1879721 nadC 7681386 nadC Streptococcus pneumoniae P1031 nicotinate-nucleotide pyrophosphorylase YP_002739102.1 1878849 R 488223 CDS YP_002739103.1 225857592 7681327 1879958..1881268 1 NC_012467.1 identified by match to protein family HMM PF03600; match to protein family HMM PF07158; membrane protein 1881268 7681327 SPP_2055 Streptococcus pneumoniae P1031 membrane protein YP_002739103.1 1879958 D 488223 CDS YP_002739104.1 225857593 7682631 complement(1881633..1881764) 1 NC_012467.1 hypothetical protein 1881764 7682631 SPP_2056 Streptococcus pneumoniae P1031 hypothetical protein YP_002739104.1 1881633 R 488223 CDS YP_002739105.1 225857594 7681274 complement(1882286..1883014) 1 NC_012467.1 identified by match to protein family HMM PF00392; match to protein family HMM PF07702; GntR family transcriptional regulator 1883014 7681274 SPP_2057 Streptococcus pneumoniae P1031 GntR family transcriptional regulator YP_002739105.1 1882286 R 488223 CDS YP_002739106.1 225857595 7682729 1883172..1884581 1 NC_012467.1 identified by match to protein family HMM PF00232; glycosyl hydrolase, family protein 1 1884581 7682729 SPP_2058 Streptococcus pneumoniae P1031 glycosyl hydrolase, family protein 1 YP_002739106.1 1883172 D 488223 CDS YP_002739107.1 225857596 7681897 1884599..1885894 1 NC_012467.1 identified by match to protein family HMM PF02378; match to protein family HMM TIGR00410; phosphotransferase system system, cellobiose-specific IIC component 1885894 7681897 SPP_2059 Streptococcus pneumoniae P1031 phosphotransferase system system, cellobiose-specific IIC component YP_002739107.1 1884599 D 488223 CDS YP_002739108.1 225857597 7680846 1885899..1886207 1 NC_012467.1 identified by match to protein family HMM PF02302; lichenan-specific phosphotransferase enzyme iib component (pts system lichenan-specific eiib component) (eiib-lic) 1886207 7680846 SPP_2060 Streptococcus pneumoniae P1031 lichenan-specific phosphotransferase enzyme iib component (pts system lichenan-specific eiib component) (eiib-lic) YP_002739108.1 1885899 D 488223 CDS YP_002739109.1 225857598 7681751 1886204..1886512 1 NC_012467.1 identified by match to protein family HMM PF02255; lichenan-specific phosphotransferase enzyme iia component (pts system lichenan-specific eiia component) (eiia-lic) (eiii-lic) 1886512 7681751 SPP_2061 Streptococcus pneumoniae P1031 lichenan-specific phosphotransferase enzyme iia component (pts system lichenan-specific eiia component) (eiia-lic) (eiii-lic) YP_002739109.1 1886204 D 488223 CDS YP_002739110.1 225857599 7680981 complement(1887420..1890071) 1 NC_012467.1 identified by match to protein family HMM PF00465; bifunctional acetaldehyde-CoA/alcohol dehydrogenase 1890071 7680981 SPP_2062 Streptococcus pneumoniae P1031 bifunctional acetaldehyde-CoA/alcohol dehydrogenase YP_002739110.1 1887420 R 488223 CDS YP_002739111.1 225857600 7681459 complement(1890370..1890780) 1 NC_012467.1 identified by match to protein family HMM PF02493; morn motif family protein 1890780 7681459 SPP_2063 Streptococcus pneumoniae P1031 morn motif family protein YP_002739111.1 1890370 R 488223 CDS YP_002739112.1 225857601 7681320 complement(1890782..1891210) 1 NC_012467.1 identified by match to protein family HMM PF01451; phosphotyrosine protein phosphatase 1891210 7681320 SPP_2064 Streptococcus pneumoniae P1031 phosphotyrosine protein phosphatase YP_002739112.1 1890782 R 488223 CDS YP_002739113.1 225857602 7681807 complement(1891256..1891555) 1 NC_012467.1 member of preprotein translocase; forms a heterotrimer with SecD and SecF; links the SecD/SecF/YajC/YidC complex with the SecY/SecE/SecG complex; preprotein translocase subunit YajC 1891555 yajC 7681807 yajC Streptococcus pneumoniae P1031 preprotein translocase subunit YajC YP_002739113.1 1891256 R 488223 CDS YP_002739114.1 225857603 7681675 complement(1891672..1893648) 1 NC_012467.1 catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase; transketolase 1893648 tkt2 7681675 tkt2 Streptococcus pneumoniae P1031 transketolase YP_002739114.1 1891672 R 488223 CDS YP_002739115.1 225857604 7680833 complement(1893762..1894853) 1 NC_012467.1 putative L-ascorbate 6-phosphate lactonase 1894853 7680833 SPP_2067 Streptococcus pneumoniae P1031 putative L-ascorbate 6-phosphate lactonase YP_002739115.1 1893762 R 488223 CDS YP_002739116.1 225857605 7682814 complement(1894965..1896638) 1 NC_012467.1 identified by match to protein family HMM PF00874; match to protein family HMM PF08279; transcriptional regulator, BglG family 1896638 7682814 SPP_2068 Streptococcus pneumoniae P1031 transcriptional regulator, BglG family YP_002739116.1 1894965 R 488223 CDS YP_002739117.1 225857606 7682602 complement(1896817..1897521) 1 NC_012467.1 catalyzes the formation of D-xylulose 5-phosphate from L-ribulose 5-phosphate in the L-arabinose and L-ascorbate degradation pathways; L-ribulose-5-phosphate 4-epimerase 1897521 araD 7682602 araD Streptococcus pneumoniae P1031 L-ribulose-5-phosphate 4-epimerase YP_002739117.1 1896817 R 488223 CDS YP_002739118.1 225857607 7682162 complement(1897523..1898386) 1 NC_012467.1 L-xylulose 5-phosphate 3-epimerase activity not yet demonstrated; may be involved in the utilization of 2,3-diketo-L-gulonate; putative L-xylulose 5-phosphate 3-epimerase 1898386 7682162 SPP_2070 Streptococcus pneumoniae P1031 putative L-xylulose 5-phosphate 3-epimerase YP_002739118.1 1897523 R 488223 CDS YP_002739119.1 225857608 7681147 complement(1898390..1899055) 1 NC_012467.1 catalyzes the formation of L-xylulose-5-phosphate from 3-keto-L-gulonate-6-phosphate in anaerobic L-ascorbate utilization; 3-keto-L-gulonate-6-phosphate decarboxylase 1899055 ulaD 7681147 ulaD Streptococcus pneumoniae P1031 3-keto-L-gulonate-6-phosphate decarboxylase YP_002739119.1 1898390 R 488223 CDS YP_002739120.1 225857609 7681032 complement(1899072..1899557) 1 NC_012467.1 identified by match to protein family HMM PF00359; ascorbate-specific phosphotransferase enzyme iia component (pts system ascorbate-specific eiia component) 1899557 7681032 SPP_2072 Streptococcus pneumoniae P1031 ascorbate-specific phosphotransferase enzyme iia component (pts system ascorbate-specific eiia component) YP_002739120.1 1899072 R 488223 CDS YP_002739121.1 225857610 7682018 complement(1899634..1899915) 1 NC_012467.1 identified by match to protein family HMM PF02302; ascorbate-specific phosphotransferase enzyme iib component (ascorbate-specific pts system eiib component) 1899915 7682018 SPP_2073 Streptococcus pneumoniae P1031 ascorbate-specific phosphotransferase enzyme iib component (ascorbate-specific pts system eiib component) YP_002739121.1 1899634 R 488223 CDS YP_002739122.1 225857611 7682331 complement(1899938..1901395) 1 NC_012467.1 membrane component; functions with enzymes IIB (sgaB; ulaB) and IIA (sgaA; ulaC) enzyme I and HPr for anaerobic utilization and uptake of L-ascorbate; sgaTBA are regulated by yifQ as well as Crp and Fnr; PTS system ascorbate-specific transporter subunit IIC 1901395 7682331 SPP_2074 Streptococcus pneumoniae P1031 PTS system ascorbate-specific transporter subunit IIC YP_002739122.1 1899938 R 488223 CDS YP_002739123.1 225857612 7681739 complement(1901526..1902149) 1 NC_012467.1 hypothetical protein 1902149 7681739 SPP_2075 Streptococcus pneumoniae P1031 hypothetical protein YP_002739123.1 1901526 R 488223 CDS YP_002739124.1 225857613 7681173 complement(1902200..1903186) 1 NC_012467.1 identified by match to protein family HMM PF01424; jag protein 1903186 7681173 SPP_2076 Streptococcus pneumoniae P1031 jag protein YP_002739124.1 1902200 R 488223 CDS YP_002739125.1 225857614 7681620 complement(1903205..1904035) 1 NC_012467.1 identified by match to protein family HMM PF02096; match to protein family HMM TIGR03592; membrane protein OxaA 1 1904035 7681620 SPP_2077 Streptococcus pneumoniae P1031 membrane protein OxaA 1 YP_002739125.1 1903205 R 488223 CDS YP_002739126.1 225857615 7682539 complement(1904004..1904375) 1 NC_012467.1 protein component of RNaseP which catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'terminus; this enzyme also cleaves other RNA substrates; ribonuclease P 1904375 rnpA 7682539 rnpA Streptococcus pneumoniae P1031 ribonuclease P YP_002739126.1 1904004 R 488223 CDS YP_002739127.1 225857616 7681070 complement(1904392..1904523) 1 NC_012467.1 hypothetical protein 1904523 7681070 SPP_2079 Streptococcus pneumoniae P1031 hypothetical protein YP_002739127.1 1904392 R 488223 CDS YP_002739128.1 225857617 7682436 complement(1904524..1905714) 1 NC_012467.1 AckA utilizes acetate and can acetylate CheY which increases signal strength during flagellar rotation; utilizes magnesium and ATP; also involved in conversion of acetate to aceyl-CoA; acetate kinase 1905714 ackA 7682436 ackA Streptococcus pneumoniae P1031 acetate kinase YP_002739128.1 1904524 R 488223 CDS YP_002739129.1 225857618 7681968 complement(1905765..1906718) 1 NC_012467.1 adenine-specific DNA methylase 1906718 7681968 SPP_2081 Streptococcus pneumoniae P1031 adenine-specific DNA methylase YP_002739129.1 1905765 R 488223 CDS YP_002739130.1 225857619 7681357 1906787..1906936 1 NC_012467.1 identified by glimmer; putative; hypothetical protein 1906936 7681357 SPP_2082 Streptococcus pneumoniae P1031 hypothetical protein YP_002739130.1 1906787 D 488223 CDS YP_002739131.1 225857620 7680777 complement(1906977..1907159) 1 NC_012467.1 identified by glimmer; putative; hypothetical protein 1907159 7680777 SPP_2083 Streptococcus pneumoniae P1031 hypothetical protein YP_002739131.1 1906977 R 488223 CDS YP_002739132.1 225857621 7680673 complement(1907510..1907923) 1 NC_012467.1 hypothetical protein 1907923 7680673 SPP_2085 Streptococcus pneumoniae P1031 hypothetical protein YP_002739132.1 1907510 R 488223 CDS YP_002739133.1 225857622 7682247 complement(1907901..1908362) 1 NC_012467.1 competence protein ComGF 1908362 7682247 SPP_2086 Streptococcus pneumoniae P1031 competence protein ComGF YP_002739133.1 1907901 R 488223 CDS YP_002739134.1 225857623 7680962 complement(1908325..1908585) 1 NC_012467.1 hypothetical protein 1908585 7680962 SPP_2087 Streptococcus pneumoniae P1031 hypothetical protein YP_002739134.1 1908325 R 488223 CDS YP_002739135.1 225857624 7680865 complement(1908590..1908994) 1 NC_012467.1 identified by match to protein family HMM TIGR02532; competence protein CglD 1908994 7680865 SPP_2088 Streptococcus pneumoniae P1031 competence protein CglD YP_002739135.1 1908590 R 488223 CDS YP_002739136.1 225857625 7680801 complement(1908987..1909313) 1 NC_012467.1 identified by match to protein family HMM PF07963; match to protein family HMM TIGR02532; competence protein CglC 1909313 7680801 SPP_2089 Streptococcus pneumoniae P1031 competence protein CglC YP_002739136.1 1908987 R 488223 CDS YP_002739137.1 225857626 7682642 complement(1909315..1910163) 1 NC_012467.1 identified by match to protein family HMM PF00482; competence protein CglB 1910163 7682642 SPP_2090 Streptococcus pneumoniae P1031 competence protein CglB YP_002739137.1 1909315 R 488223 CDS YP_002739138.1 225857627 7682860 complement(1910279..1911220) 1 NC_012467.1 identified by match to protein family HMM PF00437; putative ABC transporter subunit ComYA 1911220 7682860 SPP_2091 Streptococcus pneumoniae P1031 putative ABC transporter subunit ComYA YP_002739138.1 1910279 R 488223 CDS YP_002739139.1 225857628 7682207 complement(1911296..1911661) 1 NC_012467.1 identified by match to protein family HMM PF06279; hypothetical protein 1911661 7682207 SPP_2092 Streptococcus pneumoniae P1031 hypothetical protein YP_002739139.1 1911296 R 488223 CDS YP_002739140.1 225857629 7681149 complement(1911812..1912870) 1 NC_012467.1 identified by match to protein family HMM PF00107; match to protein family HMM PF08240; alcohol dehydrogenase, zinc-containing 1912870 7681149 SPP_2093 Streptococcus pneumoniae P1031 alcohol dehydrogenase, zinc-containing YP_002739140.1 1911812 R 488223 CDS YP_002739141.1 225857630 7681476 complement(1913033..1914184) 1 NC_012467.1 identified by match to protein family HMM PF01979; match to protein family HMM TIGR00221; N-acetylglucosamine-6-phosphate deacetylase 1914184 nagA 7681476 nagA Streptococcus pneumoniae P1031 N-acetylglucosamine-6-phosphate deacetylase YP_002739141.1 1913033 R 488223 CDS YP_002739142.1 225857631 7680984 complement(1914337..1916154) 1 NC_012467.1 identified by match to protein family HMM PF01757; acyltransferase 1916154 7680984 SPP_2095 Streptococcus pneumoniae P1031 acyltransferase YP_002739142.1 1914337 R 488223 CDS YP_002739143.1 225857632 7681802 complement(1916255..1917397) 1 NC_012467.1 Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr); queuine tRNA-ribosyltransferase 1917397 tgt 7681802 tgt Streptococcus pneumoniae P1031 queuine tRNA-ribosyltransferase YP_002739143.1 1916255 R 488223 CDS YP_002739144.1 225857633 7681765 1917527..1918384 1 NC_012467.1 identified by match to protein family HMM PF06161; hypothetical protein 1918384 7681765 SPP_2097 Streptococcus pneumoniae P1031 hypothetical protein YP_002739144.1 1917527 D 488223 CDS YP_002739145.1 225857634 7681520 complement(1918412..1919056) 1 NC_012467.1 catalyzes the removal of 5-oxoproline from various penultimate amino acid residues except L-proline; pyrrolidone-carboxylate peptidase 1919056 pcp2 7681520 pcp2 Streptococcus pneumoniae P1031 pyrrolidone-carboxylate peptidase YP_002739145.1 1918412 R 488223 CDS YP_002739146.1 225857635 7681895 complement(1919163..1919531) 1 NC_012467.1 identified by match to protein family HMM PF06993; hypothetical protein 1919531 7681895 SPP_2099 Streptococcus pneumoniae P1031 hypothetical protein YP_002739146.1 1919163 R 488223 CDS YP_002739147.1 225857636 7681841 1920285..1920407 1 NC_012467.1 identified by glimmer; putative; hypothetical protein 1920407 7681841 SPP_2102 Streptococcus pneumoniae P1031 hypothetical protein YP_002739147.1 1920285 D 488223 CDS YP_002739148.1 225857637 7681960 complement(1920393..1921571) 1 NC_012467.1 identified by match to protein family HMM PF01476; LysM domain-containing protein 1921571 7681960 SPP_2101 Streptococcus pneumoniae P1031 LysM domain-containing protein YP_002739148.1 1920393 R 488223 CDS YP_002739149.1 225857638 7682780 complement(1921737..1922357) 1 NC_012467.1 identified by match to protein family HMM PF00702; match to protein family HMM TIGR01549; HAD-superfamily hydrolase, subfamily IA, variant 1 1922357 7682780 SPP_2103 Streptococcus pneumoniae P1031 HAD-superfamily hydrolase, subfamily IA, variant 1 YP_002739149.1 1921737 R 488223 CDS YP_002739150.1 225857639 7681220 complement(1922361..1923641) 1 NC_012467.1 identified by match to protein family HMM PF01554; match to protein family HMM PF03023; match to protein family HMM TIGR00797; multi antimicrobial extrusion 1923641 7681220 SPP_2104 Streptococcus pneumoniae P1031 multi antimicrobial extrusion YP_002739150.1 1922361 R 488223 CDS YP_002739151.1 225857640 7681549 complement(1923702..1925186) 1 NC_012467.1 catalyzes the formation of L-threonine from O-phospho-L-homoserine; threonine synthase 1925186 thrC 7681549 thrC Streptococcus pneumoniae P1031 threonine synthase YP_002739151.1 1923702 R 488223 CDS YP_002739152.1 225857641 7682465 complement(1925262..1926539) 1 NC_012467.1 hypothetical protein 1926539 7682465 SPP_2106 Streptococcus pneumoniae P1031 hypothetical protein YP_002739152.1 1925262 R 488223 CDS YP_002739153.1 225857642 7680741 complement(1933008..1933442) 1 NC_012467.1 cytidine/deoxycytidylate deaminase family protein 1933442 7680741 SPP_2123 Streptococcus pneumoniae P1031 cytidine/deoxycytidylate deaminase family protein YP_002739153.1 1933008 R 488223 CDS YP_002739154.1 225857643 7680905 complement(1933456..1934916) 1 NC_012467.1 Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation; glutamyl-tRNA synthetase 1934916 gltX 7680905 gltX Streptococcus pneumoniae P1031 glutamyl-tRNA synthetase YP_002739154.1 1933456 R 488223 CDS YP_002739155.1 225857644 7681049 complement(1935040..1936389) 1 NC_012467.1 functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis; catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate; member of PGI family; glucose-6-phosphate isomerase 1936389 pgi 7681049 pgi Streptococcus pneumoniae P1031 glucose-6-phosphate isomerase YP_002739155.1 1935040 R 488223 CDS YP_002739156.1 225857645 7681413 complement(1936376..1936555) 1 NC_012467.1 hypothetical protein 1936555 7681413 SPP_2126 Streptococcus pneumoniae P1031 hypothetical protein YP_002739156.1 1936376 R 488223 CDS YP_002739157.1 225857646 7681546 complement(1936559..1937248) 1 NC_012467.1 identified by match to protein family HMM PF00117; match to protein family HMM PF07722; glutamine amidotransferase 1937248 7681546 SPP_2127 Streptococcus pneumoniae P1031 glutamine amidotransferase YP_002739157.1 1936559 R 488223 CDS YP_002739158.1 225857647 7682026 complement(1937387..1939153) 1 NC_012467.1 identified by match to protein family HMM PF00005; match to protein family HMM PF00664; ABC transporter ATP-binding protein/permease 1939153 7682026 SPP_2128 Streptococcus pneumoniae P1031 ABC transporter ATP-binding protein/permease YP_002739158.1 1937387 R 488223 CDS YP_002739159.1 225857648 7681012 1939291..1939614 1 NC_012467.1 transposase 1939614 7681012 SPP_2129 Streptococcus pneumoniae P1031 transposase YP_002739159.1 1939291 D 488223 CDS YP_002739160.1 225857649 7682353 complement(1939944..1941638) 1 NC_012467.1 identified by match to protein family HMM PF00005; match to protein family HMM PF00664; ABC transporter ATP-binding protein/permease 1941638 7682353 SPP_2130 Streptococcus pneumoniae P1031 ABC transporter ATP-binding protein/permease YP_002739160.1 1939944 R 488223 CDS YP_002739161.1 225857650 7680932 complement(1941785..1944319) 1 NC_012467.1 This protein performs the mismatch recognition step during the DNA repair process; DNA mismatch repair protein MutS 1944319 mutS 7680932 mutS Streptococcus pneumoniae P1031 DNA mismatch repair protein MutS YP_002739161.1 1941785 R 488223 CDS YP_002739162.1 225857651 7680706 complement(1944370..1944816) 1 NC_012467.1 identified by match to protein family HMM PF01316; match to protein family HMM PF02863; match to protein family HMM TIGR01529; arginine repressor 1944816 argR 7680706 argR Streptococcus pneumoniae P1031 arginine repressor YP_002739162.1 1944370 R 488223 CDS YP_002739163.1 225857652 7681991 1944952..1946643 1 NC_012467.1 catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase; arginyl-tRNA synthetase 1946643 argS 7681991 argS Streptococcus pneumoniae P1031 arginyl-tRNA synthetase YP_002739163.1 1944952 D 488223 CDS YP_002739164.1 225857653 7682554 complement(1946958..1947422) 1 NC_012467.1 identified by match to protein family HMM PF01609; transposase (IS4 family) 1947422 7682554 SPP_2134 Streptococcus pneumoniae P1031 transposase (IS4 family) YP_002739164.1 1946958 R 488223 CDS YP_002739165.1 225857654 7682820 1947502..1947987 1 NC_012467.1 identified by match to protein family HMM PF06172; hypothetical protein 1947987 7682820 SPP_2135 Streptococcus pneumoniae P1031 hypothetical protein YP_002739165.1 1947502 D 488223 CDS YP_002739166.1 225857655 7681535 1948071..1948778 1 NC_012467.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00486; alkaline phosphatase synthesis transcriptional regulatory proteinphoP 1948778 7681535 SPP_2136 Streptococcus pneumoniae P1031 alkaline phosphatase synthesis transcriptional regulatory proteinphoP YP_002739166.1 1948071 D 488223 CDS YP_002739167.1 225857656 7681397 1948779..1950110 1 NC_012467.1 identified by match to protein family HMM PF00512; match to protein family HMM PF02518; histidine kinase PnpS 1950110 7681397 SPP_2137 Streptococcus pneumoniae P1031 histidine kinase PnpS YP_002739167.1 1948779 D 488223 CDS YP_002739168.1 225857657 7681943 1950277..1951152 1 NC_012467.1 ABC transporter substrate-binding protein - phosphate transport 1951152 7681943 SPP_2139 Streptococcus pneumoniae P1031 ABC transporter substrate-binding protein - phosphate transport YP_002739168.1 1950277 D 488223 CDS YP_002739169.1 225857658 7682665 complement(1951145..1951276) 1 NC_012467.1 identified by glimmer; putative; hypothetical protein 1951276 7682665 SPP_2138 Streptococcus pneumoniae P1031 hypothetical protein YP_002739169.1 1951145 R 488223 CDS YP_002739170.1 225857659 7682676 1951270..1952133 1 NC_012467.1 identified by match to protein family HMM PF00528; match to protein family HMM TIGR02138; phosphate ABC transporter permease 1952133 pstC2 7682676 pstC2 Streptococcus pneumoniae P1031 phosphate ABC transporter permease YP_002739170.1 1951270 D 488223 CDS YP_002739171.1 225857660 7681291 1952126..1952941 1 NC_012467.1 identified by match to protein family HMM PF00528; match to protein family HMM TIGR00974; phosphate ABC transporter permease 1952941 pstA2 7681291 pstA2 Streptococcus pneumoniae P1031 phosphate ABC transporter permease YP_002739171.1 1952126 D 488223 CDS YP_002739172.1 225857661 7681701 1952943..1953695 1 NC_012467.1 ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation; phosphate transporter ATP-binding protein 1953695 pstB3 7681701 pstB3 Streptococcus pneumoniae P1031 phosphate transporter ATP-binding protein YP_002739172.1 1952943 D 488223 CDS YP_002739173.1 225857662 7682281 1953710..1954360 1 NC_012467.1 identified by match to protein family HMM PF01895; match to protein family HMM TIGR02135; phosphate transport system regulatory protein PhoU 1954360 phoU2 7682281 phoU2 Streptococcus pneumoniae P1031 phosphate transport system regulatory protein PhoU YP_002739173.1 1953710 D 488223 CDS YP_002739174.1 225857663 7680785 1954428..1954853 1 NC_012467.1 transposase, IS1380-Spn1 related, truncation 1954853 7680785 SPP_2144 Streptococcus pneumoniae P1031 transposase, IS1380-Spn1 related, truncation YP_002739174.1 1954428 D 488223 CDS YP_002739175.1 225857664 7681818 1955619..1956635 1 NC_012467.1 catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate; NAD(P)H-dependent glycerol-3-phosphate dehydrogenase 1956635 gpsA 7681818 gpsA Streptococcus pneumoniae P1031 NAD(P)H-dependent glycerol-3-phosphate dehydrogenase YP_002739175.1 1955619 D 488223 CDS YP_002739176.1 225857665 7680939 1956657..1957556 1 NC_012467.1 identified by match to protein family HMM PF00483; match to protein family HMM TIGR01099; UTP-glucose-1-phosphate uridylyltransferase 1957556 galU 7680939 galU Streptococcus pneumoniae P1031 UTP-glucose-1-phosphate uridylyltransferase YP_002739176.1 1956657 D 488223 CDS YP_002739177.1 225857666 7681442 1957974..1958906 1 NC_012467.1 identified by glimmer; putative; hypothetical protein 1958906 7681442 SPP_2148 Streptococcus pneumoniae P1031 hypothetical protein YP_002739177.1 1957974 D 488223 CDS YP_002739178.1 225857667 7681140 complement(1959009..1959686) 1 NC_012467.1 identified by match to protein family HMM PF01694; peptidase, S54 1959686 7681140 SPP_2149 Streptococcus pneumoniae P1031 peptidase, S54 YP_002739178.1 1959009 R 488223 CDS YP_002739179.1 225857668 7682501 complement(1959670..1960209) 1 NC_012467.1 identified by match to protein family HMM PF01812; match to protein family HMM TIGR02727; 5-formyltetrahydrofolate cyclo-ligase 1960209 7682501 SPP_2150 Streptococcus pneumoniae P1031 5-formyltetrahydrofolate cyclo-ligase YP_002739179.1 1959670 R 488223 CDS YP_002739180.1 225857669 7681008 complement(1960221..1961351) 1 NC_012467.1 identified by match to protein family HMM PF01546; match to protein family HMM PF07687; match to protein family HMM TIGR01891; peptidase, M20/M25/M40 family 1961351 7681008 SPP_2151 Streptococcus pneumoniae P1031 peptidase, M20/M25/M40 family YP_002739180.1 1960221 R 488223 CDS YP_002739181.1 225857670 7682199 complement(1961419..1962117) 1 NC_012467.1 identified by match to protein family HMM PF00132; match to protein family HMM PF08503; galactoside O-acetyltransferase 1962117 7682199 SPP_2152 Streptococcus pneumoniae P1031 galactoside O-acetyltransferase YP_002739181.1 1961419 R 488223 CDS YP_002739182.1 225857671 7681622 complement(1962347..1963309) 1 NC_012467.1 identified by match to protein family HMM PF00892; membrane protein 1963309 7681622 SPP_2153 Streptococcus pneumoniae P1031 membrane protein YP_002739182.1 1962347 R 488223 CDS YP_002739183.1 225857672 7681315 complement(1963323..1965788) 1 NC_012467.1 identified by match to protein family HMM PF00905; match to protein family HMM PF00912; penicillin-binding protein 1B 1965788 7681315 SPP_2154 Streptococcus pneumoniae P1031 penicillin-binding protein 1B YP_002739183.1 1963323 R 488223 CDS YP_002739184.1 225857673 7681791 1965930..1967186 1 NC_012467.1 catalyzes the formation of tyrosyl-tRNA(Tyr) from tyrosine and tRNA(Tyr); tyrosyl-tRNA synthetase 1967186 tyrS 7681791 tyrS Streptococcus pneumoniae P1031 tyrosyl-tRNA synthetase YP_002739184.1 1965930 D 488223 CDS YP_002739185.1 225857674 7680640 complement(1967264..1969327) 1 NC_012467.1 identified by match to protein family HMM PF00122; match to protein family HMM PF00702; match to protein family HMM TIGR01494; match to protein family HMM TIGR01525; P-type ATPase-metal/cation transport 1969327 7680640 SPP_2156 Streptococcus pneumoniae P1031 P-type ATPase-metal/cation transport YP_002739185.1 1967264 R 488223 CDS YP_002739186.1 225857675 7681557 complement(1969329..1969607) 1 NC_012467.1 hypothetical protein 1969607 7681557 SPP_2157 Streptococcus pneumoniae P1031 hypothetical protein YP_002739186.1 1969329 R 488223 CDS YP_002739187.1 225857676 7681721 1969759..1970607 1 NC_012467.1 identified by match to protein family HMM PF08241; 23S rRNA m1G745 methyltransferase 1970607 7681721 SPP_2158 Streptococcus pneumoniae P1031 23S rRNA m1G745 methyltransferase YP_002739187.1 1969759 D 488223 CDS YP_002739188.1 225857677 7682781 1971229..1971801 1 NC_012467.1 hypothetical protein 1971801 7682781 SPP_2159 Streptococcus pneumoniae P1031 hypothetical protein YP_002739188.1 1971229 D 488223 CDS YP_002739189.1 225857678 7681998 complement(1972845..1975103) 1 NC_012467.1 identified by match to protein family HMM PF00343; match to protein family HMM TIGR02093; glycogen phosphorylase 1975103 7681998 SPP_2160 Streptococcus pneumoniae P1031 glycogen phosphorylase YP_002739189.1 1972845 R 488223 CDS YP_002739190.1 225857679 7682649 complement(1975129..1976646) 1 NC_012467.1 amylomaltase; acts to release glucose from maltodextrins; 4-alpha-glucanotransferase 1976646 malQ 7682649 malQ Streptococcus pneumoniae P1031 4-alpha-glucanotransferase YP_002739190.1 1975129 R 488223 CDS YP_002739191.1 225857680 7681113 1977196..1978467 1 NC_012467.1 identified by match to protein family HMM PF01547; maltose/maltodextrin-binding protein 1978467 7681113 SPP_2162 Streptococcus pneumoniae P1031 maltose/maltodextrin-binding protein YP_002739191.1 1977196 D 488223 CDS YP_002739192.1 225857681 7681056 1978578..1979870 1 NC_012467.1 identified by match to protein family HMM PF00528; match to protein family HMM PF05154; maltodextrin transport system permease protein MalC 1979870 7681056 SPP_2163 Streptococcus pneumoniae P1031 maltodextrin transport system permease protein MalC YP_002739192.1 1978578 D 488223 CDS YP_002739193.1 225857682 7681394 1979872..1980714 1 NC_012467.1 identified by match to protein family HMM PF00528; maltose/maltodextrin ABC transporter permease 1980714 7681394 SPP_2164 Streptococcus pneumoniae P1031 maltose/maltodextrin ABC transporter permease YP_002739193.1 1979872 D 488223 CDS YP_002739194.1 225857683 7680632 1980967..1981767 1 NC_012467.1 maltodextrose utilization protein MalA 1981767 7680632 SPP_2165 Streptococcus pneumoniae P1031 maltodextrose utilization protein MalA YP_002739194.1 1980967 D 488223 CDS YP_002739195.1 225857684 7680831 1981777..1982763 1 NC_012467.1 identified by match to protein family HMM PF00356; match to protein family HMM PF00532; HTH-type transcriptional regulator MalR (Maltose operontranscriptional repressor) 1982763 7680831 SPP_2166 Streptococcus pneumoniae P1031 HTH-type transcriptional regulator MalR (Maltose operontranscriptional repressor) YP_002739195.1 1981777 D 488223 CDS YP_002739196.1 225857685 7682826 1982830..1983501 1 NC_012467.1 hypothetical protein 1983501 7682826 SPP_2167 Streptococcus pneumoniae P1031 hypothetical protein YP_002739196.1 1982830 D 488223 CDS YP_002739197.1 225857686 7682728 complement(1983505..1984446) 1 NC_012467.1 identified by match to protein family HMM PF02588; YitT family protein 1984446 7682728 SPP_2168 Streptococcus pneumoniae P1031 YitT family protein YP_002739197.1 1983505 R 488223 CDS YP_002739198.1 225857687 7682403 complement(1984424..1986187) 1 NC_012467.1 catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes; aspartyl-tRNA synthetase 1986187 aspS 7682403 aspS Streptococcus pneumoniae P1031 aspartyl-tRNA synthetase YP_002739198.1 1984424 R 488223 CDS YP_002739199.1 225857688 7681192 complement(1986539..1986769) 1 NC_012467.1 hypothetical protein 1986769 7681192 SPP_2170 Streptococcus pneumoniae P1031 hypothetical protein YP_002739199.1 1986539 R 488223 CDS YP_002739200.1 225857689 7681359 complement(1986787..1987428) 1 NC_012467.1 identified by match to protein family HMM PF02517; caax amino protease family 1987428 7681359 SPP_2171 Streptococcus pneumoniae P1031 caax amino protease family YP_002739200.1 1986787 R 488223 CDS YP_002739201.1 225857690 7680807 complement(1987440..1988174) 1 NC_012467.1 hypothetical protein 1988174 7680807 SPP_2172 Streptococcus pneumoniae P1031 hypothetical protein YP_002739201.1 1987440 R 488223 CDS YP_002739202.1 225857691 7681956 complement(1988177..1988374) 1 NC_012467.1 hypothetical protein 1988374 7681956 SPP_2173 Streptococcus pneumoniae P1031 hypothetical protein YP_002739202.1 1988177 R 488223 CDS YP_002739203.1 225857692 7682479 complement(1988374..1988580) 1 NC_012467.1 identified by match to protein family HMM PF01381; hypothetical protein 1988580 7682479 SPP_2174 Streptococcus pneumoniae P1031 hypothetical protein YP_002739203.1 1988374 R 488223 CDS YP_002739204.1 225857693 7681543 complement(1988590..1988904) 1 NC_012467.1 hypothetical protein 1988904 7681543 SPP_2175 Streptococcus pneumoniae P1031 hypothetical protein YP_002739204.1 1988590 R 488223 CDS YP_002739205.1 225857694 7681407 complement(1989057..1989203) 1 NC_012467.1 chlorohydrolase 1989203 7681407 SPP_2176 Streptococcus pneumoniae P1031 chlorohydrolase YP_002739205.1 1989057 R 488223 CDS YP_002739206.1 225857695 7682165 complement(1989200..1990489) 1 NC_012467.1 catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG; histidyl-tRNA synthetase 1990489 hisS 7682165 hisS Streptococcus pneumoniae P1031 histidyl-tRNA synthetase YP_002739206.1 1989200 R 488223 CDS YP_002739207.1 225857696 7681508 complement(1990586..1991815) 1 NC_012467.1 identified by match to protein family HMM PF07690; transporter, major facilitator family 1991815 7681508 SPP_2178 Streptococcus pneumoniae P1031 transporter, major facilitator family YP_002739207.1 1990586 R 488223 CDS YP_002739208.1 225857697 7681434 complement(1992008..1992859) 1 NC_012467.1 identified by match to protein family HMM TIGR01716; positive transcriptional regulator of glucosyltransferase and Spp phenotype 1992859 7681434 SPP_2179 Streptococcus pneumoniae P1031 positive transcriptional regulator of glucosyltransferase and Spp phenotype YP_002739208.1 1992008 R 488223 CDS YP_002739209.1 225857698 7681930 1992983..1993324 1 NC_012467.1 identified by match to protein family HMM PF01883; hypothetical protein 1993324 7681930 SPP_2180 Streptococcus pneumoniae P1031 hypothetical protein YP_002739209.1 1992983 D 488223 CDS YP_002739210.1 225857699 7682355 1993388..1993732 1 NC_012467.1 identified by glimmer; putative; hypothetical protein 1993732 7682355 SPP_2181 Streptococcus pneumoniae P1031 hypothetical protein YP_002739210.1 1993388 D 488223 CDS YP_002739211.1 225857700 7682829 complement(1993758..1995461) 1 NC_012467.1 catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis; dihydroxy-acid dehydratase 1995461 ilvD 7682829 ilvD Streptococcus pneumoniae P1031 dihydroxy-acid dehydratase YP_002739211.1 1993758 R 488223 CDS YP_002739212.1 225857701 7681616 complement(1995694..1996626) 1 NC_012467.1 identified by match to protein family HMM PF02779; match to protein family HMM PF02780; transketolase, C- subunit 1996626 7681616 SPP_2183 Streptococcus pneumoniae P1031 transketolase, C- subunit YP_002739212.1 1995694 R 488223 CDS YP_002739213.1 225857702 7681902 complement(1996623..1997480) 1 NC_012467.1 identified by match to protein family HMM PF00456; transketolase 1997480 7681902 SPP_2184 Streptococcus pneumoniae P1031 transketolase YP_002739213.1 1996623 R 488223 CDS YP_002739214.1 225857703 7681387 complement(1997484..1998830) 1 NC_012467.1 membrane component; functions with enzymes IIB (sgaB; ulaB) and IIA (sgaA; ulaC) enzyme I and HPr for anaerobic utilization and uptake of L-ascorbate; sgaTBA are regulated by yifQ as well as Crp and Fnr; PTS system ascorbate-specific transporter subunit IIC 1998830 ulaA 7681387 ulaA Streptococcus pneumoniae P1031 PTS system ascorbate-specific transporter subunit IIC YP_002739214.1 1997484 R 488223 CDS YP_002739215.1 225857704 7680941 complement(1998843..1999127) 1 NC_012467.1 identified by match to protein family HMM PF02302; phosphotransferase system, galactitol-specific IIB component 1999127 7680941 SPP_2186 Streptococcus pneumoniae P1031 phosphotransferase system, galactitol-specific IIB component YP_002739215.1 1998843 R 488223 CDS YP_002739216.1 225857705 7681983 complement(1999131..2001161) 1 NC_012467.1 identified by match to protein family HMM PF00359; match to protein family HMM PF00874; transcriptional regulator, BglG family protein 2001161 7681983 SPP_2187 Streptococcus pneumoniae P1031 transcriptional regulator, BglG family protein YP_002739216.1 1999131 R 488223 CDS YP_002739217.1 225857706 7682021 2001352..2002359 1 NC_012467.1 identified by match to protein family HMM PF01145; integral membrane protein 2002359 7682021 SPP_2188 Streptococcus pneumoniae P1031 integral membrane protein YP_002739217.1 2001352 D 488223 CDS YP_002739218.1 225857707 7682087 2002362..2002562 1 NC_012467.1 hypothetical protein 2002562 7682087 SPP_2189 Streptococcus pneumoniae P1031 hypothetical protein YP_002739218.1 2002362 D 488223 CDS YP_002739219.1 225857708 7682312 2002714..2002896 1 NC_012467.1 some L32 proteins have zinc finger motifs consisting of CXXC while others do not; 50S ribosomal protein L32 2002896 rpmF 7682312 rpmF Streptococcus pneumoniae P1031 50S ribosomal protein L32 YP_002739219.1 2002714 D 488223 CDS YP_002739220.1 225857709 7682236 2002912..2003061 1 NC_012467.1 in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif; 50S ribosomal protein L33 2003061 rpmG 7682236 rpmG Streptococcus pneumoniae P1031 50S ribosomal protein L33 YP_002739220.1 2002912 D 488223 CDS YP_002739221.1 225857710 7682567 complement(2003483..2005363) 1 NC_012467.1 identified by match to protein family HMM PF00728; N-acetyl-beta-D-glucosaminidase 2005363 7682567 SPP_2192 Streptococcus pneumoniae P1031 N-acetyl-beta-D-glucosaminidase YP_002739221.1 2003483 R 488223 CDS YP_002739222.1 225857711 7681313 complement(2005357..2006226) 1 NC_012467.1 identified by match to protein family HMM PF00480; ROK family protein 2006226 7681313 SPP_2193 Streptococcus pneumoniae P1031 ROK family protein YP_002739222.1 2005357 R 488223 CDS YP_002739223.1 225857712 7682240 complement(2006310..2008955) 1 NC_012467.1 identified by match to protein family HMM PF01074; match to protein family HMM PF07748; glycosyl hydrolase, family 38 2008955 7682240 SPP_2194 Streptococcus pneumoniae P1031 glycosyl hydrolase, family 38 YP_002739223.1 2006310 R 488223 CDS YP_002739224.1 225857713 7680949 complement(2009046..2010326) 1 NC_012467.1 identified by match to protein family HMM PF06824; twin-arginine translocation pathway signal 2010326 7680949 SPP_2195 Streptococcus pneumoniae P1031 twin-arginine translocation pathway signal YP_002739224.1 2009046 R 488223 CDS YP_002739225.1 225857714 7681460 2010497..2012581 1 NC_012467.1 identified by match to protein family HMM PF07971; match to protein family HMM TIGR01180; antigen, cell wall surface anchor family 2012581 7681460 SPP_2196 Streptococcus pneumoniae P1031 antigen, cell wall surface anchor family YP_002739225.1 2010497 D 488223 CDS YP_002739226.1 225857715 7681154 complement(2012621..2014300) 1 NC_012467.1 FucA 2014300 7681154 SPP_2197 Streptococcus pneumoniae P1031 FucA YP_002739226.1 2012621 R 488223 CDS YP_002739227.1 225857716 7682230 complement(2014344..2014457) 1 NC_012467.1 identified by glimmer; putative; hypothetical protein 2014457 7682230 SPP_2198 Streptococcus pneumoniae P1031 hypothetical protein YP_002739227.1 2014344 R 488223 CDS YP_002739228.1 225857717 7681490 2015056..2016285 1 NC_012467.1 catalyzes the degradation of arginine to citruline and ammonia; arginine deiminase 2016285 arcA 7681490 arcA Streptococcus pneumoniae P1031 arginine deiminase YP_002739228.1 2015056 D 488223 CDS YP_002739229.1 225857718 7680665 2016343..2017359 1 NC_012467.1 catalyzes the formation of ornithine and carbamylphosphate from citrulline in the arginine catabolic pathway; ornithine carbamoyltransferase 2017359 argF 7680665 argF Streptococcus pneumoniae P1031 ornithine carbamoyltransferase YP_002739229.1 2016343 D 488223 CDS YP_002739230.1 225857719 7681487 2017524..2018471 1 NC_012467.1 catalyzes the reversible synthesis of carbamate and ATP from carbamoyl phosphate and ADP; carbamate kinase 2018471 arcC 7681487 arcC Streptococcus pneumoniae P1031 carbamate kinase YP_002739230.1 2017524 D 488223 CDS YP_002739231.1 225857720 7682426 2018682..2020193 1 NC_012467.1 identified by match to protein family HMM PF03606; arginine-ornithine antiporter 2020193 7682426 SPP_2202 Streptococcus pneumoniae P1031 arginine-ornithine antiporter YP_002739231.1 2018682 D 488223 CDS YP_002739232.1 225857721 7680857 2020215..2021546 1 NC_012467.1 identified by match to protein family HMM PF01546; match to protein family HMM TIGR01887; hypothetical protein 2021546 7680857 SPP_2203 Streptococcus pneumoniae P1031 hypothetical protein YP_002739232.1 2020215 D 488223 CDS YP_002739233.1 225857722 7682304 complement(2022229..2022378) 1 NC_012467.1 hypothetical protein 2022378 7682304 SPP_2205 Streptococcus pneumoniae P1031 hypothetical protein YP_002739233.1 2022229 R 488223 CDS YP_002739234.1 225857723 7680893 complement(2022880..2023779) 1 NC_012467.1 identified by match to protein family HMM PF01145; spfh domain/band 7 family 2023779 7680893 SPP_2207 Streptococcus pneumoniae P1031 spfh domain/band 7 family YP_002739234.1 2022880 R 488223 CDS YP_002739235.1 225857724 7682577 complement(2023909..2025060) 1 NC_012467.1 identified by match to protein family HMM PF00465; NAD-dependent methanol dehydrogenase (medh) 2025060 7682577 SPP_2208 Streptococcus pneumoniae P1031 NAD-dependent methanol dehydrogenase (medh) YP_002739235.1 2023909 R 488223 CDS YP_002739236.1 225857725 7682662 complement(2025206..2026972) 1 NC_012467.1 catalyzes the conversion of the aldose L-fucose into the corresponding ketose L-fuculose; L-fucose isomerase 2026972 fucI 7682662 fucI Streptococcus pneumoniae P1031 L-fucose isomerase YP_002739236.1 2025206 R 488223 CDS YP_002739237.1 225857726 7680808 complement(2027029..2030145) 1 NC_012467.1 identified by match to protein family HMM PF00754; match to protein family HMM PF08306; match to protein family HMM PF08307; glycosyl hydrolase family 98 2030145 7680808 SPP_2210 Streptococcus pneumoniae P1031 glycosyl hydrolase family 98 YP_002739237.1 2027029 R 488223 CDS YP_002739238.1 225857727 7682198 complement(2030155..2032449) 1 NC_012467.1 large secreted protein 2032449 7682198 SPP_2211 Streptococcus pneumoniae P1031 large secreted protein YP_002739238.1 2030155 R 488223 CDS YP_002739239.1 225857728 7682364 complement(2032508..2033308) 1 NC_012467.1 identified by match to protein family HMM PF03613; mannose permease iid component (pts system mannose-specific eiidcomponent) (eiid-man) (eii-m-man) 2033308 7682364 SPP_2212 Streptococcus pneumoniae P1031 mannose permease iid component (pts system mannose-specific eiidcomponent) (eiid-man) (eii-m-man) YP_002739239.1 2032508 R 488223 CDS YP_002739240.1 225857729 7681730 complement(2033305..2034078) 1 NC_012467.1 identified by match to protein family HMM PF03609; phosphotransferase system sugar-specific EII component 2034078 7681730 SPP_2213 Streptococcus pneumoniae P1031 phosphotransferase system sugar-specific EII component YP_002739240.1 2033305 R 488223 CDS YP_002739241.1 225857730 7681255 complement(2034103..2034573) 1 NC_012467.1 identified by match to protein family HMM PF03830; PTS system, IIB component 2034573 7681255 SPP_2214 Streptococcus pneumoniae P1031 PTS system, IIB component YP_002739241.1 2034103 R 488223 CDS YP_002739242.1 225857731 7680647 complement(2034564..2035007) 1 NC_012467.1 identified by match to protein family HMM PF03610; PTS system, IIA component 2035007 7680647 SPP_2215 Streptococcus pneumoniae P1031 PTS system, IIA component YP_002739242.1 2034564 R 488223 CDS YP_002739243.1 225857732 7681615 complement(2034988..2035428) 1 NC_012467.1 identified by match to protein family HMM PF05025; fucose operon FucU protein 2035428 7681615 SPP_2216 Streptococcus pneumoniae P1031 fucose operon FucU protein YP_002739243.1 2034988 R 488223 CDS YP_002739244.1 225857733 7680637 complement(2035440..2036078) 1 NC_012467.1 catalyzes the formation of glycerone phosphate and (S)-lactaldehyde from L-fuculose 1-phosphate; L-fuculose phosphate aldolase 2036078 7680637 SPP_2217 Streptococcus pneumoniae P1031 L-fuculose phosphate aldolase YP_002739244.1 2035440 R 488223 CDS YP_002739245.1 225857734 7682077 complement(2036193..2037596) 1 NC_012467.1 identified by match to protein family HMM PF00370; rhamnulokinase (Rhamnulose kinase) 2037596 7682077 SPP_2218 Streptococcus pneumoniae P1031 rhamnulokinase (Rhamnulose kinase) YP_002739245.1 2036193 R 488223 CDS YP_002739246.1 225857735 7682626 2037772..2038545 1 NC_012467.1 identified by match to protein family HMM PF00455; match to protein family HMM PF08220; match to protein family HMM PF08279; regulator of fucose operon 2038545 7682626 SPP_2219 Streptococcus pneumoniae P1031 regulator of fucose operon YP_002739246.1 2037772 D 488223 CDS YP_002739247.1 225857736 7681972 complement(2039707..2041212) 1 NC_012467.1 identified by match to protein family HMM PF01297; match to protein family HMM PF09223; zinc-binding lipoprotein AdcA 2041212 7681972 SPP_2220 Streptococcus pneumoniae P1031 zinc-binding lipoprotein AdcA YP_002739247.1 2039707 R 488223 CDS YP_002739248.1 225857737 7680887 complement(2041222..2042028) 1 NC_012467.1 identified by match to protein family HMM PF00950; zinc ABC transporter permease 2042028 7680887 SPP_2221 Streptococcus pneumoniae P1031 zinc ABC transporter permease YP_002739248.1 2041222 R 488223 CDS YP_002739249.1 225857738 7681711 complement(2042021..2042725) 1 NC_012467.1 identified by match to protein family HMM PF00005; zinc transport system ATP-binding protein AdcC 2042725 7681711 SPP_2222 Streptococcus pneumoniae P1031 zinc transport system ATP-binding protein AdcC YP_002739249.1 2042021 R 488223 CDS YP_002739250.1 225857739 7682315 complement(2042725..2043165) 1 NC_012467.1 identified by match to protein family HMM PF01022; match to protein family HMM PF01047; match to protein family HMM PF01325; match to protein family HMM PF01978; match to protein family HMM PF08279; putative transcriptional repressor 2043165 7682315 SPP_2223 Streptococcus pneumoniae P1031 putative transcriptional repressor YP_002739250.1 2042725 R 488223 CDS YP_002739251.1 225857740 7680829 2043150..2043287 1 NC_012467.1 hypothetical protein 2043287 7680829 SPP_2224 Streptococcus pneumoniae P1031 hypothetical protein YP_002739251.1 2043150 D 488223 CDS YP_002739252.1 225857741 7681638 complement(2043320..2044588) 1 NC_012467.1 identified by match to protein family HMM PF04914; match to protein family HMM PF04915; match to protein family HMM PF04918; D-alanine transfer from undecaprenol-phosphate to the poly 2044588 7681638 SPP_2225 Streptococcus pneumoniae P1031 D-alanine transfer from undecaprenol-phosphate to the poly YP_002739252.1 2043320 R 488223 CDS YP_002739253.1 225857742 7680971 complement(2044581..2044820) 1 NC_012467.1 D-alanyl carrier protein subunit; involved in the incorporation of D-alanine into membrane-associated D-alanyl-lipoteichoic acid; D-alanyl carrier protein is the acceptor of activated D-alanine which it donates to a membrane acceptor(D-alanyl transferase) for incorporation into membrane lipoteichoic acid; D-alanine--poly(phosphoribitol) ligase subunit 2 2044820 dltC 7680971 dltC Streptococcus pneumoniae P1031 D-alanine--poly(phosphoribitol) ligase subunit 2 YP_002739253.1 2044581 R 488223 CDS YP_002739254.1 225857743 7680631 complement(2044834..2046078) 1 NC_012467.1 identified by match to protein family HMM PF03062; protein DltB 2046078 7680631 SPP_2227 Streptococcus pneumoniae P1031 protein DltB YP_002739254.1 2044834 R 488223 CDS YP_002739255.1 225857744 7682790 complement(2046075..2047625) 1 NC_012467.1 transfers D-alanine to the D-alanyl carrier protein during the incorporation of D-alanine into lipoteichoic acid; D-alanine--poly(phosphoribitol) ligase subunit 1 2047625 dltA 7682790 dltA Streptococcus pneumoniae P1031 D-alanine--poly(phosphoribitol) ligase subunit 1 YP_002739255.1 2046075 R 488223 CDS YP_002739256.1 225857745 7681659 complement(2047646..2047777) 1 NC_012467.1 hypothetical protein 2047777 7681659 SPP_2229 Streptococcus pneumoniae P1031 hypothetical protein YP_002739256.1 2047646 R 488223 CDS YP_002739257.1 225857746 7681567 complement(2048091..2049269) 1 NC_012467.1 identified by match to protein family HMM PF07690; permease of the major facilitator superfamily 2049269 7681567 SPP_2230 Streptococcus pneumoniae P1031 permease of the major facilitator superfamily YP_002739257.1 2048091 R 488223 CDS YP_002739258.1 225857747 7680712 complement(2049725..2051002) 1 NC_012467.1 identified by match to protein family HMM PF00078; match to protein family HMM PF08388; GBSi1, group II intron, maturase 2051002 7680712 SPP_2231 Streptococcus pneumoniae P1031 GBSi1, group II intron, maturase YP_002739258.1 2049725 R 488223 CDS YP_002739259.1 225857748 7682413 2052192..2052383 1 NC_012467.1 identified by glimmer; putative; hypothetical protein 2052383 7682413 SPP_2232 Streptococcus pneumoniae P1031 hypothetical protein YP_002739259.1 2052192 D 488223 CDS YP_002739260.1 225857749 7681822 complement(2052785..2052988) 1 NC_012467.1 identified by glimmer; putative; hypothetical protein 2052988 7681822 SPP_2233 Streptococcus pneumoniae P1031 hypothetical protein YP_002739260.1 2052785 R 488223 CDS YP_002739261.1 225857750 7682865 2053081..2053206 1 NC_012467.1 identified by glimmer; putative; hypothetical protein 2053206 7682865 SPP_2234 Streptococcus pneumoniae P1031 hypothetical protein YP_002739261.1 2053081 D 488223 CDS YP_002739262.1 225857751 7680934 complement(2053285..2053989) 1 NC_012467.1 identified by match to protein family HMM PF00230; match to protein family HMM TIGR00861; glycerol uptake facilitator protein 2053989 7680934 SPP_2235 Streptococcus pneumoniae P1031 glycerol uptake facilitator protein YP_002739262.1 2053285 R 488223 CDS YP_002739263.1 225857752 7681128 complement(2054059..2055885) 1 NC_012467.1 identified by match to protein family HMM PF01266; alpha-glycerophosphate oxidase (Glycerol-3-phosphateoxidase) (Exported protein 6) 2055885 7681128 SPP_2236 Streptococcus pneumoniae P1031 alpha-glycerophosphate oxidase (Glycerol-3-phosphateoxidase) (Exported protein 6) YP_002739263.1 2054059 R 488223 CDS YP_002739264.1 225857753 7680924 complement(2056032..2057540) 1 NC_012467.1 Converts glycerol and ADP to glycerol-3-phosphate and ADP; glycerol kinase 2057540 glpK 7680924 glpK Streptococcus pneumoniae P1031 glycerol kinase YP_002739264.1 2056032 R 488223 CDS YP_002739265.1 225857754 7681021 complement(2057699..2059108) 1 NC_012467.1 identified by match to protein family HMM PF05043; M protein trans-acting positive regulator (MGA) 2059108 7681021 SPP_2238 Streptococcus pneumoniae P1031 M protein trans-acting positive regulator (MGA) YP_002739265.1 2057699 R 488223 CDS YP_002739266.1 225857755 7682668 complement(2059117..2059251) 1 NC_012467.1 identified by glimmer; putative; hypothetical protein 2059251 7682668 SPP_2239 Streptococcus pneumoniae P1031 hypothetical protein YP_002739266.1 2059117 R 488223 CDS YP_002739267.1 225857756 7681980 2059291..2060163 1 NC_012467.1 becomes active under oxidative stress; four conserved cysteines bind a zinc atom when they are in the reduced state and the enzyme is inactive; oxidative stress results in oxidized cysteines, release of zinc, and binding of Hsp33 to aggregation-prone proteins; forms dimers and higher order oligomers; Hsp33-like chaperonin 2060163 hslO 7681980 hslO Streptococcus pneumoniae P1031 Hsp33-like chaperonin YP_002739267.1 2059291 D 488223 CDS YP_002739268.1 225857757 7681608 2060150..2061130 1 NC_012467.1 identified by match to protein family HMM PF00724; match to protein family HMM PF01180; match to protein family HMM PF01207; match to protein family HMM TIGR00737; tRNA-dihydrouridine synthase B 2061130 7681608 SPP_2241 Streptococcus pneumoniae P1031 tRNA-dihydrouridine synthase B YP_002739268.1 2060150 D 488223 CDS YP_002739269.1 225857758 7681157 complement(2061360..2063099) 1 NC_012467.1 identified by match to protein family HMM PF01473; match to protein family HMM PF04650; match to protein family HMM PF05062; match to protein family HMM TIGR01168; SigA binding protein 2063099 7681157 SPP_2242 Streptococcus pneumoniae P1031 SigA binding protein YP_002739269.1 2061360 R 488223 CDS YP_002739270.1 225857759 7682410 complement(2063178..2063705) 1 NC_012467.1 identified by match to protein family HMM PF04140; hypothetical protein 2063705 7682410 SPP_2243 Streptococcus pneumoniae P1031 hypothetical protein YP_002739270.1 2063178 R 488223 CDS YP_002739271.1 225857760 7680657 complement(2063788..2065119) 1 NC_012467.1 identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518; histidine kinase 2065119 7680657 SPP_2244 Streptococcus pneumoniae P1031 histidine kinase YP_002739271.1 2063788 R 488223 CDS YP_002739272.1 225857761 7681358 complement(2065116..2065769) 1 NC_012467.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00486; response regulator 2065769 7681358 SPP_2245 Streptococcus pneumoniae P1031 response regulator YP_002739272.1 2065116 R 488223 CDS YP_002739273.1 225857762 7681072 2065822..2066019 1 NC_012467.1 identified by glimmer; putative; hypothetical protein 2066019 7681072 SPP_2246 Streptococcus pneumoniae P1031 hypothetical protein YP_002739273.1 2065822 D 488223 CDS YP_002739274.1 225857763 7681944 2066209..2066340 1 NC_012467.1 DNA alkylation repair enzyme 2066340 7681944 SPP_2247 Streptococcus pneumoniae P1031 DNA alkylation repair enzyme YP_002739274.1 2066209 D 488223 CDS YP_002739275.1 225857764 7682484 complement(2066411..2068843) 1 NC_012467.1 identified by match to protein family HMM PF00004; match to protein family HMM PF02861; match to protein family HMM PF07724; match to protein family HMM PF07728; chaperone ClpB 1 2068843 7682484 SPP_2248 Streptococcus pneumoniae P1031 chaperone ClpB 1 YP_002739275.1 2066411 R 488223 CDS YP_002739276.1 225857765 7681244 complement(2068845..2069303) 1 NC_012467.1 identified by match to protein family HMM PF05848; transcriptional regulator CtsR 2069303 7681244 SPP_2249 Streptococcus pneumoniae P1031 transcriptional regulator CtsR YP_002739276.1 2068845 R 488223 CDS YP_002739277.1 225857766 7682470 complement(2069422..2070150) 1 NC_012467.1 identified by match to protein family HMM PF00005; anion ABC transporter ATP-binding protein 2070150 7682470 SPP_2250 Streptococcus pneumoniae P1031 anion ABC transporter ATP-binding protein YP_002739277.1 2069422 R 488223 CDS YP_002739278.1 225857767 7681909 complement(2070150..2071157) 1 NC_012467.1 identified by match to protein family HMM PF09084; ABC transporter substrate-binding protein 2071157 7681909 SPP_2251 Streptococcus pneumoniae P1031 ABC transporter substrate-binding protein YP_002739278.1 2070150 R 488223 CDS YP_002739279.1 225857768 7681218 complement(2071195..2071956) 1 NC_012467.1 identified by match to protein family HMM PF00528; ABC transporter permease 2071956 7681218 SPP_2252 Streptococcus pneumoniae P1031 ABC transporter permease YP_002739279.1 2071195 R 488223 CDS YP_002739280.1 225857769 7681246 complement(2071916..2072206) 1 NC_012467.1 hypothetical protein 2072206 7681246 SPP_2253 Streptococcus pneumoniae P1031 hypothetical protein YP_002739280.1 2071916 R 488223 CDS YP_002739281.1 225857770 7682773 complement(2072462..2073808) 1 NC_012467.1 identified by match to protein family HMM PF01473; match to protein family HMM PF05257; match to protein family HMM PF08460; choline binding protein D 2073808 7682773 SPP_2254 Streptococcus pneumoniae P1031 choline binding protein D YP_002739281.1 2072462 R 488223 CDS YP_002739282.1 225857771 7681452 complement(2073897..2074163) 1 NC_012467.1 identified by match to protein family HMM PF06257; hypothetical protein 2074163 7681452 SPP_2255 Streptococcus pneumoniae P1031 hypothetical protein YP_002739282.1 2073897 R 488223 CDS YP_002739283.1 225857772 7681516 complement(2074165..2075517) 1 NC_012467.1 unwinds double stranded DNA; replicative DNA helicase 2075517 dnaB 7681516 dnaB Streptococcus pneumoniae P1031 replicative DNA helicase YP_002739283.1 2074165 R 488223 CDS YP_002739284.1 225857773 7681200 complement(2075561..2076013) 1 NC_012467.1 in Escherichia coli this protein is wrapped around the base of the L1 stalk; 50S ribosomal protein L9 2076013 rplI 7681200 rplI Streptococcus pneumoniae P1031 50S ribosomal protein L9 YP_002739284.1 2075561 R 488223 CDS YP_002739285.1 225857774 7682041 complement(2076010..2077983) 1 NC_012467.1 identified by match to protein family HMM PF01368; match to protein family HMM PF02272; DHH subfamily 1 protein 2077983 7682041 SPP_2258 Streptococcus pneumoniae P1031 DHH subfamily 1 protein YP_002739285.1 2076010 R 488223 CDS YP_002739286.1 225857775 7682723 complement(2078119..2078667) 1 NC_012467.1 identified by match to protein family HMM PF02482; match to protein family HMM TIGR00741; ribosome-associated protein Y 2078667 7682723 SPP_2259 Streptococcus pneumoniae P1031 ribosome-associated protein Y YP_002739286.1 2078119 R 488223 CDS YP_002739287.1 225857776 7681747 complement(2078747..2079409) 1 NC_012467.1 putative competence protein ComF 2079409 7681747 SPP_2260 Streptococcus pneumoniae P1031 putative competence protein ComF YP_002739287.1 2078747 R 488223 CDS YP_002739288.1 225857777 7682317 complement(2079406..2080704) 1 NC_012467.1 identified by match to protein family HMM PF00271; match to protein family HMM PF04851; superfamily II ATP-dependent DNA/RNA helicase required for DNA uptake 2080704 7682317 SPP_2261 Streptococcus pneumoniae P1031 superfamily II ATP-dependent DNA/RNA helicase required for DNA uptake YP_002739288.1 2079406 R 488223 CDS YP_002739289.1 225857778 7681352 2080760..2081395 1 NC_012467.1 identified by match to protein family HMM PF01205; match to protein family HMM PF09186; match to protein family HMM TIGR00257; hypothetical protein 2081395 7681352 SPP_2262 Streptococcus pneumoniae P1031 hypothetical protein YP_002739289.1 2080760 D 488223 CDS YP_002739290.1 225857779 7682545 2081680..2082600 1 NC_012467.1 identified by match to protein family HMM PF00291; match to protein family HMM TIGR01136; match to protein family HMM TIGR01139; cysteine synthase A 2082600 cysK 7682545 cysK Streptococcus pneumoniae P1031 cysteine synthase A YP_002739290.1 2081680 D 488223 CDS YP_002739291.1 225857780 7682264 complement(2082797..2083066) 1 NC_012467.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; transposase 2083066 7682264 SPP_2264 Streptococcus pneumoniae P1031 transposase YP_002739291.1 2082797 R 488223 CDS YP_002739292.1 225857781 7681862 complement(2083651..2083938) 1 NC_012467.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop; identified by match to protein family HMM PF05717; transposase 2083938 7681862 SPP_2265 Streptococcus pneumoniae P1031 transposase YP_002739292.1 2083651 R 488223 CDS YP_002739293.1 225857782 7681507 complement(2084184..2085224) 1 NC_012467.1 EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu; elongation factor Ts 2085224 tsf 7681507 tsf Streptococcus pneumoniae P1031 elongation factor Ts YP_002739293.1 2084184 R 488223 CDS YP_002739294.1 225857783 7682025 complement(2085303..2086082) 1 NC_012467.1 one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit; 30S ribosomal protein S2 2086082 rpsB 7682025 rpsB Streptococcus pneumoniae P1031 30S ribosomal protein S2 YP_002739294.1 2085303 R 488223 CDS YP_002739295.1 225857784 7681898 complement(2086306..2087484) 1 NC_012467.1 identified by match to protein family HMM PF05257; general stress protein GSP-781 2087484 7681898 SPP_2268 Streptococcus pneumoniae P1031 general stress protein GSP-781 YP_002739295.1 2086306 R 488223 CDS YP_002739296.1 225857785 7681119 complement(2087578..2088072) 1 NC_012467.1 identified by match to protein family HMM PF04093; match to protein family HMM TIGR03426; rod shape-determining protein MreD 2088072 mreD 7681119 mreD Streptococcus pneumoniae P1031 rod shape-determining protein MreD YP_002739296.1 2087578 R 488223 CDS YP_002739297.1 225857786 7681296 complement(2088072..2088890) 1 NC_012467.1 in some organisms this protein is a transmembrane protein while in others it is periplasmic; involved in some organisms with other components of the MreBCD complex and with penicillin binding proteins in the periplasm or cell wall; rod shape-determining protein MreC 2088890 mreC 7681296 mreC Streptococcus pneumoniae P1031 rod shape-determining protein MreC YP_002739297.1 2088072 R 488223 CDS YP_002739298.1 225857787 7682857 complement(2088949..2089743) 1 NC_012467.1 identified by match to protein family HMM PF02361; ABC transporter permease 2089743 7682857 SPP_2271 Streptococcus pneumoniae P1031 ABC transporter permease YP_002739298.1 2088949 R 488223 CDS YP_002739299.1 225857788 7680791 complement(2089736..2090575) 1 NC_012467.1 with CbiNQ forms the ABC transporter for cobalt import; Streptococcus has two adjacent copies of this gene; cobalt transporter ATP-binding subunit 2090575 cbiO 7680791 cbiO Streptococcus pneumoniae P1031 cobalt transporter ATP-binding subunit YP_002739299.1 2089736 R 488223 CDS YP_002739300.1 225857789 7681482 complement(2090560..2091387) 1 NC_012467.1 with CbiNQ forms the ABC transporter for cobalt import; Streptococcus has two adjacent copies of this gene; cobalt transporter ATP-binding subunit 2091387 cbiO 7681482 cbiO Streptococcus pneumoniae P1031 cobalt transporter ATP-binding subunit YP_002739300.1 2090560 R 488223 CDS YP_002739301.1 225857790 7680794 complement(2091384..2091929) 1 NC_012467.1 identified by match to protein family HMM PF01066; match to protein family HMM TIGR00560; CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase 2091929 pgsA 7680794 pgsA Streptococcus pneumoniae P1031 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase YP_002739301.1 2091384 R 488223 CDS YP_002739302.1 225857791 7681478 complement(2091940..2092761) 1 NC_012467.1 hypothetical protein 2092761 7681478 SPP_2275 Streptococcus pneumoniae P1031 hypothetical protein YP_002739302.1 2091940 R 488223 CDS YP_002739303.1 225857792 7680968 complement(2092803..2094086) 1 NC_012467.1 identified by match to protein family HMM PF00675; match to protein family HMM PF05193; peptidase, M16 family 2094086 7680968 SPP_2276 Streptococcus pneumoniae P1031 peptidase, M16 family YP_002739303.1 2092803 R 488223 CDS YP_002739304.1 225857793 7682214 complement(2094083..2095333) 1 NC_012467.1 identified by match to protein family HMM PF05193; peptidase, M16 family 2095333 7682214 SPP_2277 Streptococcus pneumoniae P1031 peptidase, M16 family YP_002739304.1 2094083 R 488223 CDS YP_002739305.1 225857794 7681163 2095492..2095860 1 NC_012467.1 identified by match to protein family HMM TIGR02988; S4 domain protein YaaA, putative 2095860 7681163 SPP_2278 Streptococcus pneumoniae P1031 S4 domain protein YaaA, putative YP_002739305.1 2095492 D 488223 CDS YP_002739306.1 225857795 7682645 2095863..2096960 1 NC_012467.1 Required for DNA replication; binds preferentially to single-stranded, linear DNA; recombination protein F 2096960 recF 7682645 recF Streptococcus pneumoniae P1031 recombination protein F YP_002739306.1 2095863 D 488223 CDS YP_002739307.1 225857796 7681786 complement(2097011..2098489) 1 NC_012467.1 catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate; inosine 5'-monophosphate dehydrogenase 2098489 guaB 7681786 guaB Streptococcus pneumoniae P1031 inosine 5'-monophosphate dehydrogenase YP_002739307.1 2097011 R 488223 CDS YP_002739308.1 225857797 7681312 complement(2098641..2099666) 1 NC_012467.1 catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; tryptophanyl-tRNA synthetase II 2099666 trpS 7681312 trpS Streptococcus pneumoniae P1031 tryptophanyl-tRNA synthetase II YP_002739308.1 2098641 R 488223 CDS YP_002739309.1 225857798 7681971 2099872..2101494 1 NC_012467.1 identified by match to protein family HMM PF00005; ATPase component of ABC transporters with duplicated ATPase domains 2101494 7681971 SPP_2282 Streptococcus pneumoniae P1031 ATPase component of ABC transporters with duplicated ATPase domains YP_002739309.1 2099872 D 488223 CDS YP_002739310.1 225857799 7681219 2101556..2104108 1 NC_012467.1 ABC transporter permease 2104108 7681219 SPP_2283 Streptococcus pneumoniae P1031 ABC transporter permease YP_002739310.1 2101556 D 488223 CDS YP_002739311.1 225857800 7682202 complement(2104551..2104889) 1 NC_012467.1 phage infection protein 2104889 7682202 SPP_2285 Streptococcus pneumoniae P1031 phage infection protein YP_002739311.1 2104551 R 488223 CDS YP_002739312.1 225857801 7681759 complement(2104974..2105741) 1 NC_012467.1 hypothetical protein 2105741 7681759 SPP_2286 Streptococcus pneumoniae P1031 hypothetical protein YP_002739312.1 2104974 R 488223 CDS YP_002739313.1 225857802 7682750 2105920..2106462 1 NC_012467.1 identified by match to protein family HMM PF00440; TetR family transcriptional regulator 2106462 7682750 SPP_2287 Streptococcus pneumoniae P1031 TetR family transcriptional regulator YP_002739313.1 2105920 D 488223 CDS YP_002739314.1 225857803 7680771 complement(2106705..2107457) 1 NC_012467.1 identified by match to protein family HMM PF00072; match to protein family HMM PF04397; response regulator 2107457 7680771 SPP_2290 Streptococcus pneumoniae P1031 response regulator YP_002739314.1 2106705 R 488223 CDS YP_002739315.1 225857804 7681777 complement(2107454..2108779) 1 NC_012467.1 identified by match to protein family HMM PF02518; ComD 2108779 7681777 SPP_2291 Streptococcus pneumoniae P1031 ComD YP_002739315.1 2107454 R 488223 CDS YP_002739316.1 225857805 7682261 complement(2108800..2108925) 1 NC_012467.1 identified by match to protein family HMM PF03047; hypothetical protein 2108925 7682261 SPP_2292 Streptococcus pneumoniae P1031 hypothetical protein YP_002739316.1 2108800 R 488223 CDS YP_002739317.1 225857806 7680727 complement(2109207..2109686) 1 NC_012467.1 SPOUT methyltransferase family protein; crystal structure shows homodimer; in Escherichia coli this protein methylates pseudouridine at position 1915 of the 23S ribosomal RNA; rRNA large subunit methyltransferase 2109686 7680727 SPP_2294 Streptococcus pneumoniae P1031 rRNA large subunit methyltransferase YP_002739317.1 2109207 R 488223 CDS YP_002739318.1 225857807 7681537 2109869..2111050 1 NC_012467.1 identified by match to protein family HMM PF00089; trypsin domain protein 2111050 7681537 SPP_2295 Streptococcus pneumoniae P1031 trypsin domain protein YP_002739318.1 2109869 D 488223 CDS YP_002739319.1 225857808 7681384 2111108..2111866 1 NC_012467.1 identified by match to protein family HMM PF02195; match to protein family HMM TIGR00180; stage 0 sporulation protein J 2111866 7681384 SPP_2296 Streptococcus pneumoniae P1031 stage 0 sporulation protein J YP_002739319.1 2111108 D 488223 CDS